CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_020990	Streptomyces albidoflavus, complete sequence	32 crisprs	cas6e,cas5,cas7,cse2gr11,cas8e,cas3HD,csa3,DinG,cas3,WYL,c2c9_V-U4,DEDDh,Cas9_archaeal,cas4	5	24	2	0

1. NC_020990

CRISPR-Cas detection and classification

Crispr_ID: NC_020990_1

• CRISPR_ID: NC_020990_1
• CRISPR_location: 801256-801350
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_1

Consensus_repeat	Method
CACCACACCCAGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NC_020990_1

>1.1|801289|29|NC_020990|CRISPRCasFinder
TCCTGGACCGGCACGGTGCACCGGAACCG

CRISPR arrays and Neighbor proteins around NC_020990_1

CRISPR arrays

The CRISPR arrays of NC_020990_1

>merge|NC_020990|1|801256-801350|CRISPRCasFinder
CACCACACCCAGCCCGGCCGGCGCTTGAGGCCATCCTGGACCGGCACGGTGCACCGGAACCGCACCACATCCAGCCCGGCCGGCGCTTGAGGCCA

>NC_020990|1|1|801256-801350|CRISPRCasFinder
CACCACACCCAGCCCGGCCGGCGCTTGAGGCCA	TCCTGGACCGGCACGGTGCACCGGAACCG
CACCACATCCAGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003951657.1|802824_804399_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187556
NC_020990.1|WP_030767072.1|810811_811933_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NC_020990.1|WP_003951651.1|809927_810731_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224045
NC_020990.1|WP_003951658.1|801418_802792_-|deoxyribodipyrimidine-photo-lyase	unknown	unknown	gnl|CDD|223492
NC_020990.1|WP_015506876.1|793731_795186_-|MFS-transporter	unknown	unknown	gnl|CDD|129794
NC_020990.1|WP_015506878.1|799347_800352_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133379
NC_020990.1|WP_008406214.1|808869_809931_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl|CDD|163581
NC_020990.1|WP_003951653.1|807820_808873_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238568
NC_020990.1|WP_003951668.1|791696_793094_+|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl|CDD|236106
NC_020990.1|WP_008411999.1|798333_798555_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003951648.1|817191_819291_-|hypothetical-protein	unknown	unknown	gnl|CDD|225177
NC_020990.1|WP_003951654.1|805383_807510_+|MMPL-family-transporter	unknown	unknown	gnl|CDD|225272
NC_020990.1|WP_015506877.1|796875_798162_+|hypothetical-protein	unknown	unknown	gnl|CDD|283013
NC_020990.1|WP_003951662.1|798622_799207_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|237125
NC_020990.1|WP_003951669.1|790212_791019_-|tyrosine-protein-phosphatase	unknown	unknown	gnl|CDD|379135
NC_020990.1|WP_003951649.1|811939_816838_-|DNA-repair-ATPase	unknown	unknown	gnl|CDD|378861
NC_020990.1|WP_003951667.1|793232_793649_+|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NC_020990.1|WP_003951665.1|796039_796879_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NC_020990.1|WP_003951656.1|804587_805094_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_020990.1|WP_015506875.1|791086_791509_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_030767072.1|810811_811933_+|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	1.1296e-31
NC_020990.1|WP_003951651.1|809927_810731_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	5.57233e-104
NC_020990.1|WP_003951658.1|801418_802792_-|deoxyribodipyrimidine-photo-lyase	gnl|CDD|223492	COG0415, PhrB, Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair].	8.99556e-125
NC_020990.1|WP_015506876.1|793731_795186_-|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.67969e-61
NC_020990.1|WP_015506878.1|799347_800352_+|MerR-family-transcriptional-regulator	gnl|CDD|133379	cd01104, HTH_MlrA-CarA, Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA. Helix-turn-helix (HTH) transcription regulator MlrA (merR-like regulator A), N-terminal domain. The MlrA protein, also known as YehV, has been shown to control cell-cell aggregation by co-regulating the expression of curli and extracellular matrix production in Escherichia coli and Salmonella typhimurium. Its close homolog, CarA from Myxococcus xanthus, is involved in activation of the carotenoid biosynthesis genes by light. These proteins belong to the MerR superfamily of transcription regulators that promote expression of several stress regulon genes by reconfiguring the spacer between the -35 and -10 promoter elements. Their conserved N-terminal domains contain predicted HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules. Many MlrA- and CarA-like proteins in this group appear to lack the long dimerization helix seen in the N-terminal domains of typical MerR-like proteins.	2.13739e-20
NC_020990.1|WP_008406214.1|808869_809931_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl|CDD|163581	TIGR03869, transport_system_permease_protein, proposed F420-0 ABC transporter, permease protein. his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.	7.28632e-83
NC_020990.1|WP_003951653.1|807820_808873_+|ABC-transporter-substrate-binding-protein	gnl|CDD|238568	cd01148, TroA_a, Metal binding protein TroA_a. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	2.8141e-89
NC_020990.1|WP_003951668.1|791696_793094_+|dihydrolipoyl-dehydrogenase	gnl|CDD|236106	PRK07818, PRK07818, dihydrolipoamide dehydrogenase; Reviewed.	0
NC_020990.1|WP_003951648.1|817191_819291_-|hypothetical-protein	gnl|CDD|225177	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown].	1.06332e-42
NC_020990.1|WP_003951654.1|805383_807510_+|MMPL-family-transporter	gnl|CDD|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	3.90925e-73
NC_020990.1|WP_015506877.1|796875_798162_+|hypothetical-protein	gnl|CDD|283013	pfam05231, MASE1, MASE1. Predicted integral membrane sensory domain found in histidine kinases, diguanylate cyclases and other bacterial signaling proteins. This entry also includes members of the 8 transmembrane UhpB type (8TMR-UT) domain family.	2.72734e-36
NC_020990.1|WP_003951662.1|798622_799207_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|237125	PRK12519, PRK12519, RNA polymerase sigma factor; Provisional.	5.83831e-40
NC_020990.1|WP_003951669.1|790212_791019_-|tyrosine-protein-phosphatase	gnl|CDD|379135	pfam13350, Y_phosphatase3, Tyrosine phosphatase family. This family is closely related to the pfam00102 and pfam00782 families.	3.55818e-62
NC_020990.1|WP_003951649.1|811939_816838_-|DNA-repair-ATPase	gnl|CDD|378861	pfam12458, DUF3686, ATPase involved in DNA repair. This domain family is found in bacteria, and is approximately 450 amino acids in length. There are two conserved sequence motifs: DVF and SPNGED.	0
NC_020990.1|WP_003951667.1|793232_793649_+|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.71905e-25
NC_020990.1|WP_003951665.1|796039_796879_+|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	4.83894e-37
NC_020990.1|WP_003951656.1|804587_805094_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	6.4305e-17
NC_020990.1|WP_003951657.1|802824_804399_-|SDR-family-oxidoreductase	gnl|CDD|187556	cd05245, SDR_a2, atypical (a) SDRs, subgroup 2. This subgroup contains atypical SDRs, one member is identified as Escherichia coli protein ybjT, function unknown. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif consensus that generally matches the extended SDRs, TGXXGXXG, but lacks the characteristic active site residues of the SDRs. This subgroup has basic residues (HXXXR) in place of the active site motif YXXXK, these may have a catalytic role. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.75793e-145

Protein sequences

>NC_020990.1|WP_015506878.1|799347_800352_+|MerR-family-transcriptional-regulator
MVNVMESRPSHPAPADPVPDAGLTTGTVARRLGVSPTTLRSWDRRYGLGPAAREDGRHRRWTPRDVALLEEMCRLTGTGVPPGEAARAAQHAFGHPAQAAPRLPVPAQAPRPGAAGSGLPLGTVRQECRGLARAAVRLDAPAVEARLALVVERLGTAAAWEEVMAPALRAVGRKWETAGERYVEVEHLLSWHVSSALRRVPPAPATTGPPVLLACVPEEQHTLPVEALAAGLGERGVPLRMFGGAVPAGALDDAVRRTGPAAVVLWSQSRDTADRRLARAVAGRAWGVKGARGGASLLLAGPGWAGPTPGGVLRPRSLREALRLLGAGEAAERG
>NC_020990.1|WP_003951662.1|798622_799207_-|sigma-70-family-RNA-polymerase-sigma-factor
MTTVATTPLPPAPSAAQEAEIAAGIRVGDARCLALAYQRWGGLVQGLAARSLGDPLEAEDVTQQVFLAAWRGGAHYRPERGPLAAWLVGIARHKIADALASRTRRTALTAAAAGLPQGPDPAAQPEICLDRALVRAELARLPDPHRRVLWMAYYGELTQAEIAARTGLPLGTVKSHARRALHRLRASLERAESE
>NC_020990.1|WP_008411999.1|798333_798555_+|hypothetical-protein
MASIDLDKVLDKAWAEKSLPEILAAPVSALKGVSDRDGELLDEAFGVKTVSDLAGLKYARWAQALAALDTSAK
>NC_020990.1|WP_015506877.1|796875_798162_+|hypothetical-protein
MTPRPDPPRRWWRPARPRDGGPADSGTGDAPGAHEPAPPEEAAPSGFTVRPHPPDGASPERTGSWRAGLSLEQLRRSSEAGPDREGRPAALSVRVLRLMTLILAVALAYYGAGRLGLLRQVVVEGATVTPLWLPSGVAVAALFAFGPRITPGIALGMLAVTSSISPVSGYSVLMAVGNTLAPLASWYLLRLVGFRPSLERLRDGLALVFLGALGGMTVSAAVGTGTLLATDKILTSHAWPVWAAWWAGDALGVLVVVPVLVVLIRPRLPRDALGWVELLGLFAVTAALTWVAIYSPLDLLFLVFPLLIWAALRFELTGSAPAALIVSVLAVTAATNQQGPFAGRAMGEIMVNLQAFNVSVALTGLLLSSLVTERRHVRERIEDACQELAEVVDTLAPGASGRRARGAGTLGPEEGEGHGRSGAGWGAD
>NC_020990.1|WP_003951665.1|796039_796879_+|serine/threonine-protein-phosphatase
MNGQRPPREESADALLTRLGRLTAVARERVEVQQARVELAEALQREMLPARLPQVPGLRAAARYAPARDGLDIGGDWYDGFELGDGTLGFSIGDVQGHDVEAAAFMGQVRMALRAVASTVSDPGEILGRVNDLLVSVDGPLFATCSFLRFDPATNELYSARAGHVGAVWAATGGRGGVAEDVGGLPLGIISGERYPVTRRRWTRPGAYVLLTDGVVEGPSFSIEEGLARVTQLVTAGVGLDPGSLADRVMRVAGRTGHLDDAAVLVLSHEGLAPGGGRP
>NC_020990.1|WP_015506876.1|793731_795186_-|MFS-transporter
MTPASAADPKRWWALAVIALAQLMVILDGTIVNIALPSAQRALGMPDADRQWVITAYTLAFGGLLLLGGRIADLVGRKRAFVIGLAGFAVASALGGAAAGTGTLFAARALQGAFAAVLAPSALSLLTTTFTDPRERAKAFGVYGALAGGGSGAGLLVGGLLTEYLNWRWCLYVNVPVALAALIGAQVFLRDRSGRRGGHLDVPGVLLGSGGLVALVYGFSEAGPRGWTSPWVAAPLMAGVLLLAAFVWWQHRAAGPLLPLRIFRDRSRAGAFATMGLATIGMFGVFLFLTYYFQAVLGYPPVRTGLAFMPVSVGIVIGATQIAARLLPRTAPHTLMASGMVLAAGGMVLLSRLTVHAQYVPHVLPGLLLVGLGMGLTFMPVYATATVGVPTQDTGAASAALTTVQQIGASLGTVLLNTIATGAAGRHSRAHGPADSGTALAEAMVHGFSVAYWCSAGVLLFAALVAALTVRRGKPSQAGSKPSA
>NC_020990.1|WP_003951667.1|793232_793649_+|PaaI-family-thioesterase
MNAHRPDLSDAQEILAAQPFSVYLGARLVAFGDGAAVLELDVRDELRQQNGFVHGGVLSYAADNALTFAAGTVAGAGLLTAGYSIDYLRPAQGRTLRAHATVVRPGRARVACRCDLFMLDQDGAQTLCAIAQGTIAVA
>NC_020990.1|WP_003951668.1|791696_793094_+|dihydrolipoyl-dehydrogenase
MSTHFDVVVLGAGPGGYVAAIRAAQLGLKVAVIEEKYWGGVCLNVGCIPSKALLRNAELAHLVNNEAKTFGIRIDGEVTFEYGPAFDRSRTVADGRVKGVHYLMKKNKITELDGRGTFTDDHTLRVEGPGGEQTVTFDHCVIAAGATTKLLPGTELSERVVTYEEQIMTRDLPESVIIAGAGAIGVEFAYVMHNYGVKVTIVEFLDRMVPNEDVEVSKELARRYKKLGIEVLTSTRVESIEDSGPQVRVTVSKDGQQQVLEADKVLQAIGFQPRVTGYGLENTGVALTERGAIDIDGRCRTNVPHIFAIGDVTAKLMLAHTAEAMGVIAAETIGDAETMELDYAMIPRATYCQPQIASFGYTEAQARELGYDVQVAKFPFMANGKAHGLGDTGGFVKLISDGTHGELIGGHLIGPDVTELLPELTLAQQWDLTVHEVARNVHAHPTLGEAVKEAVHGLAGHMINM
>NC_020990.1|WP_015506875.1|791086_791509_-|hypothetical-protein
MDAELAALAASGASSLVGLMVSDAWSAARGRVARLFARGGDEDQVAGELTAARDELAEADRNGDEEHRADIQEEWQLRLRRLLRADPGAAAELRAFLDEIAPAEPAAGGVVINNTVSGGTHHAPVIQVGQLGHGTFGSRG
>NC_020990.1|WP_003951669.1|790212_791019_-|tyrosine-protein-phosphatase
MDSEPTGRAVEAATVANLRDLGGIPLPGAGEGRSVRPGALLRSADLAHHDPHTDPVLTERGVQVVFDLRTTGEREAAPDILPPGARPFVGDVLGTRPGAAPARLARYLEDPVLAEQELGGGRAERLFEDAYRRMVLSPGARSAYAALVQTAADDGTHPLLFHCTAGKDRTGWGAALLLLLLGAGQDAVRSEYLAVNDAVRARYEPHVRRFVERGGDPEIAAVLTEVRPAYLDAALDALTERWGDIERYAREALRVEAALDRLRAELTV
>NC_020990.1|WP_003951658.1|801418_802792_-|deoxyribodipyrimidine-photo-lyase
MTVSIVLFTSDLRLHDQPALRAALDATDAVVPLFVRDDAVAEAGFAAPNRAAFLADCLTDLDHSLRERGGRLVIRSGDLVEEVCRVVTEADADEVHLAEGVSAFARRREERLREALESEGRRLFVHEGVTTALPPGAVTPASSDHFAVFTPYFRKWSEQHLRHPLGAPRTVRVPDGIGSEKVPARGDVRGVSAGLAAGGESEGRDRLTAWLRRDAGAYEDQHDDLAGDATSRLSPHLHFGTLSAAELVHRARRKEGAGATAFVRQLCWRDFHHQVLAARPDASHADYRAREDHWRTGRDAEQETEAWREGRTGYPIVDAAMRQLAHEGWMHNRGRLLAASFLSKTLYVDWRTGADHFLSLLVDGDIANNQMNWQWVAGTGTDTRPHRVLNPVRQAHRYDPDGAYVRRWVPELAGVEGKAVHEPWTLEGFDRAGIDYPEPVVGLSEGLDRFRRARGRD
>NC_020990.1|WP_003951657.1|802824_804399_-|SDR-family-oxidoreductase
MSSDEHPTESAPHGDGRLALVTGATGYIGGRLAPALQDAGYRVRALARTPRKLRDLPWAERAEVVQGDVTDAESVREAMRGVDVAYYLVHALGTGSDFERTDREAARIFAREAREAGVRRIVYLGGLTPEGVPESRLSPHLRSRAEVGRILLDSGVPATVLRAAVVLGSGSASFEMLRYLTERLPLMITPSWVNTRMQPVAVRDVLAYLVGSAAMPAEVNRTFDIGGPDILTYRELMQHYAAVAKLPRRVILPVPVLTPRLSSHWVGLVTPVPVAIARPLAESLRHEVVCREHDIAAYVPDTPGRPLGVDEALELAIRRVQDAQVATRWSSASVPGAPSDPLPTDPEWSGGSLYEDRRERLVDASPEALWRVVEGIGGEHGWYSFPLAWAVRGRLDRLVGGVGLRRGRRDAQHLRVGESLDFWRVEEIEQGHLLRLRAEMRLPGLAWLEMTVDRDEAGRTRYRQRAVFLPRGLAGQAYWWSVSPFHAVVFGGMARNIALTAAREENAPSSSPTAPDGTVSRPSP
>NC_020990.1|WP_003951656.1|804587_805094_+|MarR-family-transcriptional-regulator
MAGTDEETGGAGGPAGGGADLYALAVELRRMHGEVNRLAHAFAAGQGLHATDVQALGAILDAPEPMTPGRLRERLGLTSGAVTACLDRLERAGHIRRTRDTRDRRVVHLHYTEGGKALARAHFQPLATAAATARARLTQEEADAALRFLAAMNGEFARIRGPERRPGG
>NC_020990.1|WP_003951654.1|805383_807510_+|MMPL-family-transporter
MSSAARKGRTARILVPLVLLIAWLGVGGTLGPYAGKLGEVATNDQAAFLPQSAESTRVSEEQKAFSADEALPALVVWTAKDGGRLPADAREAATRTLASLADAGFTAGRPSPALASEDGEALEGVVPLRTDLDELQPVLDEIKEAAGKVPGTEAVIAGPAASQADLSDAFAGIDGLLLGVALIAVLLILLVVYRSVLLPLVIIFGAVLALGLACAVVYALAQRDVVRVDGQVQGILSILVIGAATDYALLLTARFREELSLHGDRFTAMRLAWRQSFGPITASAATVALGLLALLLSDLTNNRALGPVGAIGIVCSVFSALTFLPAALVLLGRAAYWPARPKVTGTGGSHRLWQRVADRVDRTPRKVWAITLAALVACAAFAPTLTSRGVPLDEIFVNDAPSVSAQETLSRHFPGGAGNPAVVIADAGQVDEVVAAAKKTEGVASVAPVTESGRPGGGAPRVVDGRVRIDATLQDGADSDAAKETVARLRTAVHAVDGADAVVGGYTAQQYDTQRTAEADRNLIMPVVLAIILVILIALLRSLVTPLLLVLTVALNFAATLGIASLVFTHVFGFTGTDASVPLYGFVFLVALGVDYNIFLMSRVREETALHGTREGVRRGLTTTGGVITSAGVVLAATFAALGVIPLAFLAQIAFIVAFGVLLDTLVVRSLLVPALVRDIGPASWWPGALSRRAEPAKEAAGEPRTPA
>NC_020990.1|WP_003951653.1|807820_808873_+|ABC-transporter-substrate-binding-protein
MPVAPFRRTSLAASCAVLGLLLTACGGGDSQPSDEAKGAGATTLENCGRPLTVEQPPERAVSLNQDSTEILLSLGLAGRMAGTATWTDPVLPHLAEENAKVERLADNNPSFEKVLDQEPDFVTASFESTLGKGGVATRKAFEDLGVGTYVSPADCSKSNTGDGDGSRDEPLTMADIHGEVTDLAKVFGVEERGEKLVADLTRRAEKATDGLSTKKAPEDERPTLLYWFANAEAPYMGGCCGAPGIITEAVGAKNVFDDTQDEWPQINWETVADRDPDVLVIGDLTRKSQTAESAAKKIAFLESNPATRTMTAVKEKRYVLLSGAAMNPSIRTVDGIEEVAAKLREFGFAK
>NC_020990.1|WP_008406214.1|808869_809931_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MTATAARPAAKEGRARRRPGAWTLGLLALVLLLASVSVAITIGPARVSVPDVWAVVASRFGGGESGLTPLREGIVWELRLPRTVLAAVCGAGLAVCGVVMQSLLRNPLADPFVLGVSSGASTGAVAVVVLGLGGGALSISTGAFLGALVSFGLVLLLSHSLGGTTDRVVLSGVAGMQLFSALTSFVVMFAADAEQTRGILFWLLGSLSGATWTDVWACLAVLVVALVVCGARAVQLDAFAFGAESAAALGVSVARTRLILLSVTALLTAALVSAAGAIGFVGLVLPHAARALVGTLHGRLLPVAALSGAVFLVWVDTLARTVLAPQEIPVGVVTSLIGVPAFVLIMYRTRRPS
>NC_020990.1|WP_003951651.1|809927_810731_+|ABC-transporter-ATP-binding-protein
MTGPDARSEDRPALRAERVTRSAGGRLILDGVDLEARAGGTVGLIGPNGSGKSTLLRLLAGLLAPSGGTVTVDGSTPAELGRRETARRLAVVGQHAATDTDLTVRDVVGLGRVPHRRAWAAPGAADREAVRAALERTGLVPFADRLWHTLSGGERQRAQIARALAQEPRHLLLDEPTNHLDVQHQLELMSLVAGLPVTCVVALHDLNLAAMFCDEVVVLRAGRAVVSGAPGEVLSEGLIAEVYGVRARVVADGGGTFVRFLAPEAGG
>NC_020990.1|WP_030767072.1|810811_811933_+|serine/threonine-protein-phosphatase
MNSRDEIARPDGRKDPAVDRIGRRWPAYAGVVPWALLVLGIVMDLATPKEVSGGPLIVLACVASGVIMSFRATLGLVVVAFVAELLTGFWESGTAGAQQFVDLAYVVVAGVLGLDLNRLVVRYGRRMTEVRTVAESVQLALLPEPPLRLAGYDIAASYRAAQTEARIGGDLYAVHDSPWGLRVFIGDVRGKGMGAVSTVALLLGAFREAAEDVPTLEALGARLNRRLAREAPGLGEELRMEGFTTAVLAEFPHGGELVRLLNFGHPGPYLVSGGHVRGLDAGVPNLPLGMSGFGQEVSPHEEFAFPPGSSLLFVTDGVTESRDPQGVFFDPVRGLEGMSCASAKAAVNGLLTRVDAWTGGVSTDDRAVLAVAH
>NC_020990.1|WP_003951649.1|811939_816838_-|DNA-repair-ATPase
MTTPPTAPQPQDQAAGQAAPRLDGAAYDVLRDRLAAQAGELARRAGALDARRTEAFGSTAPAATGTLTLRTAHPARAADLAALGDVLLFGVRDLPDTVTAGSGPAVGDVFSLHARDGSPLPEDAVPGLLDDPAFRTEFAALHRYYRRSRLLRLRRSGQKLLAVFRTGERVADLRVLRWSVAADGSVAFLDARGERDAREPAPGGPGVEWTPATRDDHVLGRHPYVAVAEGVGVSTVGGHLTVTTGEDDTPAHREPVAEPLQSLADADLAHARVGPLVLLRVRPYKEEEWRHLVVHTPTGAVHRLDAPDGAFRRLPDDQGVVHPGGMFLADGTGKHVEDRAGGALEFDRELRSPLGEDVLYAYHAHGLAPGLLLSYNMLRKELAAPLRCTGWARHEDGTLAVLRADGGGEPTRVHPVQLWRTPYVADTRAAAYGGEGPLARVGNPDLVRALGACLSLARTAGGATVPTTAVYRALRDDCAAVLDRHPWLGDPELGALHEPLERIRETAGQIIDEFQHVTDLTRQAAQALDEAADEAAALVRRVRGEAPKSADGWVASLTALRRAHGRILATKELRYADPGRADRLAGELGEETAAAARRAVSHLARPDAFAAHHQDAARLTEEAEALATAAEAAPLTRALDEHTERLTTVSEVVAGIDISDATVRTGILEAVAEVLGAVNRARATLAARRRALAETEGRAEFGAELALLAQATTAALAAADTPESCAAQLAALLLRVEDLESRFAEQDAFLDALAARREEIHEAFTTRGQTLADARARHTQRLADSADRVLVTLTRRLAALPDQEAVTAFLATDPMAAKVTRTIEALREADDPVRAEELAGRLKAARQEAARALRDRADLYADGGRTVRLGRHRFAVTTRPAELTLVPDGDTLAFALSGTDYRSPVTDPGFAATRPYWEQTLPSESAGLYRAEHLAARLLTDHGAEALATADLPALVRAAAEAAPEEGYERGVHDHDTVRILQALLPLHRSAGLLRFPAAERAAAQLFWAHHTAPDTRAGLTRRARSLARARAAFGPTGAEEELRAELADALAASGTPGAGSVDTGLAAAYLFEELADARPGFVTGGAARALLEKFRRTAGPAYDEDLAALGPGALPAAHQLVTAWLTAATTASGDTTEPGDLAEAAATELCPGLDRYEGDAPLTATAERLLGDHPRIHHGTLTLRLDTFLARTRHFTTRTLPGFRAYQARRAALVAAERDRLRLDQHRTGVLTSFVRNRLIDEVYLPLIGDNLAKQLGAAGAARRTDHSGLLLLLSPPGYGKTTLMEYVADRLGLLRVRVDGPAIGHRVTSLDPAEAPDATARQEIEKINFALAAGSNTLLHIDDIQHLSPELLSKFIPLCDAQRRVDGVQDGRARSYDLRGKRFAVCMTGNPYTESGHLFRVPDMLANRADVWNLGDVLTGKEEAFAQSFVENALTSHPDLAPLAGRDRADLDLFLRLARGDASARPDQLLTPCPPAERERATAVLRHLLAARETVLTVNAAYIASAAQADETRTEPPFRLQGSYRNMNRIAERISPVMDEAELAALLDDHYRAEAQTLTGGAEASLLKLAALRGRLTEEQAARWEQVCAAHVRHQAIGGADGDQLGRAVAALGLLADRLAAVEGAIRGGS
>NC_020990.1|WP_003951648.1|817191_819291_-|hypothetical-protein
MNAITWGVGAAGAAVLLILIALLLVVTRLFRKVEQGKALIVSKVRSVDVTFTGQVVLPVLHKAETLDISVKTLEISRTGREGLICRDNIRADIRIQFFLRVNKTVEDVIRVAQSIGTARASDAGALQEFFNAKFSEALKTVGKQLDFTDLYTQREEFRDRIIAVIGTDLNGYSLEDAAIDYVEQTPLAQLDAQNILDAQGIRKITELTAAEHVRTNEFQRHEEKEITRQDVDAREAILELERRRSDAEIRQRREIETLRAREEAEIARVAEEERLRAQTAFLHTEENLGVQRENQAREIAVAQKNRERVIAVESERIEKDRLLEVIARDRETELTRIAADKEVEAERRDIAEVIRERVAVDRTVAEQEESIKRLRAVEEAERDRQALVIAAEAVAQEQLVKDIKAAEAAEQAAVHRANEELTLAEARVKAAGLDAQAKLKLAEGIQAEQAAEGLARVQVQEKEADALEKTGLAEAQATEARLRAEAEGERAKALARAEGTTAQASADAAAVGEKLKAEAAGLTEKAAAMAALDEASRGHEEYRLRLAAEKEIRLAGLQAQKEVAEAQATVLATGLESADINIVGGESVFFDRIVDSVSFGKGLDALVTNSATAQRLGADWLDGTSSFTGDLTSVLSSVTSGGLRDLSASALMGRLAKEGIPADRAGELLDRAREAGLLTADATPAPAGATRNGATDTAG

Crispr_ID: NC_020990_2

• CRISPR_ID: NC_020990_2
• CRISPR_location: 1201336-1201437
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_2

Consensus_repeat	Method
AAGCCCGGCCGGCGATTGAGGCCACCC	CRISPRCasFinder

spacers of NC_020990_2

>2.1|1201363|48|NC_020990|CRISPRCasFinder
ACAGGCACCGAAGACGTGCGGCAGCAAACGCAGCAGCTCGCCCGAATC

CRISPR arrays and Neighbor proteins around NC_020990_2

CRISPR arrays

The CRISPR arrays of NC_020990_2

>merge|NC_020990|2|1201336-1201437|CRISPRCasFinder
AAGCCCGGCCGGCGATTGAGGCCACCCACAGGCACCGAAGACGTGCGGCAGCAAACGCAGCAGCTCGCCCGAATCAAGCCCGGCCGGCGATTGAGGCCACCC

>NC_020990|2|2|1201336-1201437|CRISPRCasFinder
AAGCCCGGCCGGCGATTGAGGCCACCC	ACAGGCACCGAAGACGTGCGGCAGCAAACGCAGCAGCTCGCCCGAATC
AAGCCCGGCCGGCGATTGAGGCCACCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_008406647.1|1207702_1208977_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_020990.1|WP_003951338.1|1201457_1202393_-|hypothetical-protein	unknown	unknown	gnl|CDD|378945
NC_020990.1|WP_003951342.1|1198733_1199498_-|DUF3710-domain-containing-protein	unknown	unknown	gnl|CDD|378867
NC_020990.1|WP_003951347.1|1192977_1193673_-|response-regulator	unknown	unknown	gnl|CDD|182522
NC_020990.1|WP_003951343.1|1197903_1198548_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|188483
NC_020990.1|WP_008406653.1|1211934_1212969_+|DUF3071-domain-containing-protein	unknown	unknown	gnl|CDD|378619
NC_020990.1|WP_003951341.1|1199499_1200015_-|dUTP-diphosphatase	unknown	unknown	gnl|CDD|234802
NC_020990.1|WP_003951337.1|1202405_1202702_-|DUF4193-domain-containing-protein	unknown	unknown	gnl|CDD|379391
NC_020990.1|WP_003951348.1|1192521_1192929_-|OB-fold-nucleic-acid-binding-domain-containing-protein	unknown	unknown	gnl|CDD|239934
NC_020990.1|WP_003951333.1|1206467_1207583_-|ferrochelatase	unknown	unknown	gnl|CDD|234585
NC_020990.1|WP_003951340.1|1200011_1200596_-|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NC_020990.1|WP_003951344.1|1197095_1197887_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235546
NC_020990.1|WP_003951346.1|1193702_1196261_-|sensor-histidine-kinase-KdpD	unknown	unknown	gnl|CDD|225115
NC_020990.1|WP_003951335.1|1204373_1205027_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_020990.1|WP_003951336.1|1203096_1204368_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_020990.1|WP_003951339.1|1200653_1201112_+|DUF3093-domain-containing-protein	unknown	unknown	gnl|CDD|378627
NC_020990.1|WP_003951331.1|1208903_1210253_+|FAD-binding-protein	unknown	unknown	gnl|CDD|281959
NC_020990.1|WP_015506976.1|1210272_1211457_-|hypothetical-protein	unknown	unknown	gnl|CDD|223039
NC_020990.1|WP_015506974.1|1205624_1206434_-|inositol-monophosphatase	unknown	unknown	gnl|CDD|238817
NC_020990.1|WP_015506973.1|1196283_1197027_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_008406647.1|1207702_1208977_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.43622e-19
NC_020990.1|WP_003951338.1|1201457_1202393_-|hypothetical-protein	gnl|CDD|378945	pfam12787, EcsC, EcsC protein family. Proteins in this family are related to EcsC from B. subtilis. This protein is found in an operon with EcsA and EcsB which are components of an ABC transport system. The function of this protein is unknown.	0.000127826
NC_020990.1|WP_003951342.1|1198733_1199498_-|DUF3710-domain-containing-protein	gnl|CDD|378867	pfam12502, DUF3710, Protein of unknown function (DUF3710). This family of proteins is found in bacteria. Proteins in this family are typically between 237 and 284 amino acids in length. There are two conserved sequence motifs: DLG and DGPRW.	3.32953e-75
NC_020990.1|WP_003951347.1|1192977_1193673_-|response-regulator	gnl|CDD|182522	PRK10529, PRK10529, DNA-binding transcriptional activator KdpE; Provisional.	2.18409e-84
NC_020990.1|WP_003951343.1|1197903_1198548_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	5.53277e-11
NC_020990.1|WP_008406653.1|1211934_1212969_+|DUF3071-domain-containing-protein	gnl|CDD|378619	pfam11268, DUF3071, Protein of unknown function (DUF3071). Some members in this family of proteins are annotated as DNA-binding proteins however this cannot be confirmed. Currently no function is known.	3.71985e-61
NC_020990.1|WP_003951341.1|1199499_1200015_-|dUTP-diphosphatase	gnl|CDD|234802	PRK00601, dut, dUTP diphosphatase.	4.54717e-73
NC_020990.1|WP_003951337.1|1202405_1202702_-|DUF4193-domain-containing-protein	gnl|CDD|379391	pfam13834, DUF4193, Domain of unknown function (DUF4193). This domain of unknown function contains four conserved cysteines and a conserved histidine, including a CXXXXH motif.	1.90861e-60
NC_020990.1|WP_003951348.1|1192521_1192929_-|OB-fold-nucleic-acid-binding-domain-containing-protein	gnl|CDD|239934	cd04488, RecG_wedge_OBF, RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a four-stranded (Holliday) junction in vivo and in vitro. This interconversion provides a route to repair stalled forks. The RecG monomer contains three domains. The N-terminal domain is named for its wedge structure, and may provide the specificity of RecG for binding branched-DNA structures. During the reversal of fork to Holliday junction, the wedge domain is fixed at the junction of the fork where the leading and lagging strand duplex arms meet, and is thought to promote the unwinding of the nascent leading and lagging strands. In order to form the Holliday junction, these nascent strands would be annealed, and the parental strands reannealed. The wedge domain may also be a processivity factor of RecG on these branched chain substrates.	1.683e-15
NC_020990.1|WP_003951333.1|1206467_1207583_-|ferrochelatase	gnl|CDD|234585	PRK00035, hemH, ferrochelatase; Reviewed.	1.441e-128
NC_020990.1|WP_003951340.1|1200011_1200596_-|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.00993e-11
NC_020990.1|WP_003951344.1|1197095_1197887_-|SDR-family-oxidoreductase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.99008e-77
NC_020990.1|WP_003951346.1|1193702_1196261_-|sensor-histidine-kinase-KdpD	gnl|CDD|225115	COG2205, KdpD, Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms].	0
NC_020990.1|WP_003951335.1|1204373_1205027_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.04213e-69
NC_020990.1|WP_003951336.1|1203096_1204368_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.86374e-51
NC_020990.1|WP_003951339.1|1200653_1201112_+|DUF3093-domain-containing-protein	gnl|CDD|378627	pfam11292, DUF3093, Protein of unknown function (DUF3093). This family of proteins with unknown function appears to be restricted to Actinobacteria. Some members are annotated as alanine rich membrane proteins however this cannot be confirmed.	1.44808e-48
NC_020990.1|WP_003951331.1|1208903_1210253_+|FAD-binding-protein	gnl|CDD|281959	pfam04030, ALO, D-arabinono-1,4-lactone oxidase. This domain is specific to D-arabinono-1,4-lactone oxidase EC:1.1.3.-, which is involved in the final step of the D-erythroascorbic acid biosynthesis pathway.	6.30972e-116
NC_020990.1|WP_015506976.1|1210272_1211457_-|hypothetical-protein	gnl|CDD|223039	PHA03307, PHA03307, transcriptional regulator ICP4; Provisional.	9.68209e-05
NC_020990.1|WP_015506974.1|1205624_1206434_-|inositol-monophosphatase	gnl|CDD|238817	cd01639, IMPase, IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled into inositol lipids; in eukaryotes IMPase plays a vital role in intracellular signaling. IMPase is one of the proposed targets of Li+ therapy in manic-depressive illness. This family contains some bacterial members of the inositol monophosphatase family classified as SuhB-like. E. coli SuhB has been suggested to participate in posstranscriptional control of gene expression, and its inositol monophosphatase activity doesn't appear to be sufficient for its cellular function. It has been proposed, that SuhB plays a role in the biosynthesis of phosphatidylinositol in mycobacteria.	9.87108e-98
NC_020990.1|WP_015506973.1|1196283_1197027_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	2.28118e-103

Protein sequences

>NC_020990.1|WP_003951339.1|1200653_1201112_+|DUF3093-domain-containing-protein
MHPNTPQYAERLTAPRAWWALVAIAGLTSGLIVMPLGVLAMLIGLVVGAAAGAAGLSTYGSAQIRVVGDALVAGDARIPLSALGAAEPLDAEETVAWRSHKADSRAFMLLRSYIPTAVRVEVTDPADPTPYLYLSTRDPERLAAALSPVREG
>NC_020990.1|WP_003951340.1|1200011_1200596_-|PaaI-family-thioesterase
MSGRTPALTPPDSALAPVRHPDAPAPGEPIGTHYEHCFGCGGEQPHGLHLAAKAGEGVSVTAEFLVRPEHQGAPGLAHGGLLATALDDTLGALNWLLRVISVTGRLETDYLRPVPVGTVLHLSAEVTAVDGRKIYATAEGRLNAPDGPVAVRADALFVEVKVEHFTDNGRPEEIQAAMDDPDQIRRVRAFEVNP
>NC_020990.1|WP_003951341.1|1199499_1200015_-|dUTP-diphosphatase
MTRPPLDLRVRRLHPEVPLPAYGNPGDAGADLCTTEPAVLAPGERAVLPTGIAIALPEGYAAFVHPRSGLAARCGLALVNAPGTIDAGYRGEIKVIVVNLDPREKVRFERFDRIAQLVVQQVETVRFHEVSELPGSVRAEGGFGSTGGHSAVGGGEGGNHYASVVADREGQ
>NC_020990.1|WP_003951342.1|1198733_1199498_-|DUF3710-domain-containing-protein
MFGRRKKTDSAEDTAGVTGETGQAEESADAEESATRRTALPPAPRPDGPWDASEVREPGEGRVDLGGLFVPGVEGMELRVEVAGDAIVAATVVLRDSAIQLQGFAAPKKEGIWGEVREEIGSGITQQGGIIEEVEGPLGWELRAQVPVQLPDGKSGYQVVRFVGIDGPRWFLRGVISGQGAVQPQAAGLLEQIFQDTVVVRGEGPMAPRDPIVLKLPDDAQMVPEGVQQENQQTSRFSGGMGQLARGPEITEIR
>NC_020990.1|WP_003951343.1|1197903_1198548_-|TetR/AcrR-family-transcriptional-regulator
MKATETSGEDRRRLKARQTRTALAAAALDLILERGLNAVTVEAVAQRADVTRRTFSRHFGGKEDAALDFTRDDGAAINAALRARPACEPPLVAYRRAVRDWLADTRAPGWHQLPRVRSLLALVDDEPTLFAAFERIRADAQEESVRIIAERLGTDPAEDPGPGVVVGAAAGVLTAALRQWWRGGPESAERLPDLVEQSFDVLLGEVALAAPHAP
>NC_020990.1|WP_003951344.1|1197095_1197887_-|SDR-family-oxidoreductase
MSTSAPLPSATPVSPDEFAGRTALVTGAASGIGLATARRLGQGGARVVIADYNAEGAASAAAALRDESVEASAVTVDVTDPASVEAAVRFAQDTYGALHLAVNNAGIGGESAPTGDYDIDVWNRVVRTNLDGVFYSMRYEIPALLAAGGGAIVNTASILGSVGFAGSPAYVAAKHGVVGLTKTAATEYAAQGVRINAVGPGFIDTPLLQGMDKQAYDGLVQLHPAGRLGRSEEVAEVIAFLLSDRASFVHGSYHLVDGAYTAR
>NC_020990.1|WP_015506973.1|1196283_1197027_-|ABC-transporter-ATP-binding-protein
MAGRTAGGGTLTEDAGAAAGTGEESMVKVRGLRRSYGTGEGAVHALRGVSFDIPRGELVALKGRSGSGKTTLLNLVGGLDEPDGGSVVVDGRELSGLGEKGLLELRRDRIGFIFQSFGLIPVLSAAENVGVPLRLRRAEAAEREERVALLLSLVGLADHARQRPGELSGGQQQRVAVARALANRPALLIADEPTGQLDAETGLAVMELLRAVVRSERVTVLVATHDTTLLGLADRVLELSDGELTEQ
>NC_020990.1|WP_003951346.1|1193702_1196261_-|sensor-histidine-kinase-KdpD
MGRGTLRIYLGAAPGVGKTYAMLSEAHRRVGRGTDCVIGFVAHHDRPRTLALLDGLELIEPLGGPDGDGGTPQTPEMDVEAVLARRPAVALVDELAHTNAPGARNAKRWQDVEELLAAGISVISTVNIQHLESLGDVVEAITGVRQQETVPDEVVRRADQIELVDMSPQALRRRLAHGNVYQSDKVDAALSNYFRPGNLTALRELALLWTADRADEYLQKYRGEHNIRSTWQARERIVVGLTGGPEGRTLIRRAARMAAKGSGSEILAVYIARRDGGLTTASPKELALQRTLVEDLGGTFHHVIGDDIPSALLEFARGVNATQIVLGSSRRKSWQYVFGPGVGATVARESTPDLDVHIVTHEEVGQGRGLPVARGARLGRSRILWGWFIAVCGPALLAIVLSSLDHGPGLANDVLLFLSLTVGAALVGGLLPALASAALCSALLNFYFTPPTRTLTISDPENIVAIVISFAVAVSVASVVDLAARRTHQAARLRAESEILSFLAGSVLRGATTLDALLERVRETFAMESVALLEREDDRTPWTCAGSVGPRPLERPEDADVDMPVGDHMALALCGRVLPAEDRRVLAAFAAQAAVVLDRQRLQDEADQARRLAEGNRIRTALLAAVSHDLRTPLAAIKASVTSLRSHDVAWSEQDQAELLESIEHGADRLDHLVGNLLDMSRLQTGTVTPLIREIDLDEVVPMALGGVPEGSAQLDIPETLPMVAVDPGLLERSVANVVENAVKYAPEGAPVLVAASALGDRVELRVMDRGPGVPDDAKDRIFAPFQRYGDAPRGAGVGLGLAVARGFAEAMGGTLNAEDTPGGGLTMVLTLRAVTGPRAGARTVLPAQVTS
>NC_020990.1|WP_003951347.1|1192977_1193673_-|response-regulator
MTRVLVVDDEPQIVRALELNLRARQYEVDSAGDGTTALRLAAERHPDVIVLDLGLPDMDGVDVLRGLRSWSRVPVLVLSARQSSDEKVQALDAGADDYVTKPFGMDELLARLRAAVRRTEPAAPDEEAEVVDAADFTVDLAAKRVHRQGRDVRLTPTEWHLLEVLVRNTGRLVSQKQLLQEVWGPSYGTESNYLRVYMAQLRRKLETDPAHPRHFITEPGMGYRFERRPQG
>NC_020990.1|WP_003951348.1|1192521_1192929_-|OB-fold-nucleic-acid-binding-domain-containing-protein
MSAAPRPEKPAGRFRRMLDRLSDISAPQERLESDELREEAATSGCARIDTCGDREMVTVTGTLRTVTLRPRAGVPALEAELFDGSGSLDVVWLGRRSITGIEPGRKLIASGRVAMSHGRRTLFNPKYELRPLGRE
>NC_020990.1|WP_003951338.1|1201457_1202393_-|hypothetical-protein
MTGTTPPRKFPFLKRRGDGAPSPAESDGERGLGASLEAADATDGAPGPHSGGTGTGEGPAATEPATPAPGRVAAVRDGLLRQGRNAKAGLGVLADRVIEIAPRIPVRDLHTLRAQFPGLGPEQLADKLISGAAHGTSTVGASVGAAAMLPVPPAMPAELAAEITAVAAIELKLIAELHEVYGQRPEGGATRRATAYLTSWTNERGIDVVRPLTITAALSGPLKRDLRQQITKRMIRNLPNLVPFLVGAAVGAVMNRRDTRKLAERVRQDLRAAQVPWDQLTSLPPLDRPELPPATLPHALPPAPRDDNRPT
>NC_020990.1|WP_003951337.1|1202405_1202702_-|DUF4193-domain-containing-protein
MATDYDTPRKTDDDLNEDSIEELKARRNDKSTSTVDVDEFEAAEGLELPGADLSNEELAVRVLPKQQDEFTCMSCFLVHHRSQLAREKNGQPICRDCD
>NC_020990.1|WP_003951336.1|1203096_1204368_-|HAMP-domain-containing-histidine-kinase
MAASPAPRPAPPKPTSAPPRPTWDPRRPPQQAWLRPTIRIRLTLLYGGMFLIAGILLLSIIYLLAAQAVHVGNELPFQVTSGTFTIYSDACPALSGRRFTSSGAFNDAMKLCIDHQRQQALDDLLSRSLLALVGLSVIAFAFGYAMAGRVLAPLGRITRTARSVAGSDLSRRIELDGPDDELKELADTFDDMLDRLERAFTAQQRFVANASHELRTPLAINRTLLEVQLSDPGAPPELQQLGKTLLATNERSEQLVEGLLLLARSDNQIVERKPVDLGEVATRAVEQVRGEAEQREVELRADIAEAVVQGNGVLLERIALNLTQNAVRYNLPPGEGGWVEVSTELQHGQAVLVVTNTGPVVPAYEIDQLFEPFRRLRTERTGSDKGVGLGLSIVRSVTRAHGGRITAEPREGGGLVMRVTLPL
>NC_020990.1|WP_003951335.1|1204373_1205027_-|response-regulator-transcription-factor
MRVLVVEDEQLLADAVATGLRREAMAVDVVYDGAAALERVGVNDYDVIVLDRDLPLVHGDDVCRRVVELQMPTRVLMLTASGDVSDRVEGLEIGADDYLPKPFAFTELIARVRALGRRTSVPLPPVLERAGIKLDPNRREVFRDGREIQLAPKEFAVLEVLLRSEGAVVSAEQLLEKAWDENTDPFTNVVRVTVMTLRRKLGEPAVIVTVPGSGYRI
>NC_020990.1|WP_015506974.1|1205624_1206434_-|inositol-monophosphatase
MTDPNTGLLALALEAARRAGDFLRDGRPADLAVAATKTSAIDVVTEMDIASEKMITGFLADRRPEDGFLGEEGASTEGTSGVRWIIDPLDGTVNYLYGRPAWAVSIAAERDGVTVVGVVHAPMRGETCRAVLGGGAHLDDTPIQVNTAPSLDRALVGTGFGYLAGRKAHQAAVAARIIPEVRDIRRGGSAAIDLCDVATGRLDAYYERGLNPWDYAAGELIAREAGALTGGRPGAPASTELTVAAPPGLFEPLQERLEEYGAWHDGTLA
>NC_020990.1|WP_003951333.1|1206467_1207583_-|ferrochelatase
MSDVRDATPYDALLLLSFGGPEGPDDVVPFLRNVTHGRGIPEERLKEVGQHYYLFDGISPINAQNRDLLAALRADFAEHGVELPVFWGNRNWSPYLPDTLREMAKEGHRRIAVLATSAYASYSGCRQYRENLADALAALQTEGLPVPRVDKLRHYFNHPGFLEPMIDGVLASLADLPDEVRDGAEIAFTTHSIPDAAADTSGPREVHGDGGAYVAQHLDTARVIADAVRERTGVDRPWSLVYQSRSGSPHIPWLEPDICDHLEERHAAGAPAVVMAPIGFVSDHMEVRYDLDTEATAKAAELGLPVRRSATVGADPRFAAAVRDLLLERAATERGEHPARCALGALGPSHDVCPVGCCPARSPRPAAAGLD
>NC_020990.1|WP_008406647.1|1207702_1208977_+|MFS-transporter
MPSPYRAIFSAPGSRGFSAAGFVGRLPLSMMGIGIVTMISQLTGRYGLAGALSAMVALSAALIGPQISRLVDLHGQRRVLRPATLVALAAVSGLLLSAQFSLPDWTLFLFAAGIGAVPSIGSMVRARWAALYRDQPRQLHTAYSFESVVDEACFIFGPIVSIGLSTTWFPEAGPLLAAVFLAAGVFSLTAQRSTEPVPHPREHHTKGSALRSTGLQVLVGTFVATGAIFGAIDVVTVAFAEEQGHKGAASLVLATYAAGSCLAGVVFGLLHFGGAPARRWLLGVVAMGVSMIPLQLVGNLPFLAVALFVAGLCIAPTMITTMALVEQHVPRAKLTEGMTWVSTGLAVGVALGSSVSGWVIDAAGAKAGYWVPAAAGAAAVLVGFLGYRRLSSPAPQREGPDGRAADAGQHQDGESGTHQERDLA
>NC_020990.1|WP_003951331.1|1208903_1210253_+|FAD-binding-protein
MDEQQTQGSTRTASPVRTRNGTWRNWAGTVAARPARETVPASAAELAGAVRDAAARGMRVKAVGTGHSFTAAAATDGLLIRPDLLTGIQIDHEAGTVTVAAGTPLKRLNVALAREGLSLTNMGDIMEQTVAGATSTGTHGTGRASASLSAQITALELVTADGSLLSCSREQNPELFAAARIGLGALGVITSLTFAVEPVFLLRAREEPMGFDQVTAEFDQLVAENEHFEFYWFPHTGNCSTKRNNRTPGPAAPVGRLSGWFEDEFLSNGVFQAANTLGRAVPATIPSLARLSSRALSARTYTDIPYKVFTSPRRVRFVEMEYAVPREALVPALRELRAMVDRSPLRVSFPVEVRTAPADDIALSTASGRETAYIAVHLYKGTPYQAYFTAAERIFTAHEGRPHWGKIHTRDAEYFAEVYPRFAEFTALRDRLDPDRLFGNDYLRRVLGD
>NC_020990.1|WP_015506976.1|1210272_1211457_-|hypothetical-protein
MRETTQVKEVGTRSGEEPQEEAKRIDLSVPQVAGSAVAAVAGAVAASQLGVYGTVIGAGVMSVVATTGGSVFQHLFRRTGEQIRDVAHVRPKGEPGPDVPDTFRADPEPDPLTDPAPGRVASADPATAHTVPGDPPAPVEATQLLGRIDPAAPRPADAEANQLLGQADPEATQLLSQADPGATQLLGQAGPDATRALRVPAADPAEADQATRLLRAVPEPSGPETGEFGEATTHQARTGRWKRPLISAAAVFVLAMGGITGWELVSGHALSGDSGPTISHLTGNRSQPSGDQEEEKAPAPEETPSGEAPSDGGSGTPSTQDPEDGTSSTGTPEEGTSPAPTRPGQQPGTPDDSTGDRSPTPTPTPSAGEPEQPTGQPSGGVPSGAAPEEGAPAG
>NC_020990.1|WP_008406653.1|1211934_1212969_+|DUF3071-domain-containing-protein
MPELRVVAVSNDGTRLVLKAADSTEYTLPIDERLRAAVRGDRPRLGQIEIEVESHLRPRDIQARIRAGASAEEVASLAGIPVDRVRRFEGPVLAERAFMAERARKTPVRRPGENTGPQLGEAVRERLLLRGADRDTVQWDSWRRDDGTWEVLLVYGVAGERHSASWSYDPPRRLVQAVDDEARSLIGESDDVSAPEPSFPFVPRIARLPRERPERPERGPHAVEPETEELPATAEQGGRDSLTSLLEAVPSFRGDMVVPERPAAERPLEEPEQEQEAEEPPAPAASAGSAYADVLMPRAVAAHRDRLIGSTDRQAEADGVRPGRRAAVPSWDEIVFGTRRKNKE

Crispr_ID: NC_020990_3

• CRISPR_ID: NC_020990_3
• CRISPR_location: 1220697-1220910
• CRISPR_type: Orphan
• Repeat_type: I-C,I-E,II-B:NA
• Spacer_info: 3 spacers

Consensus repeat of NC_020990_3

Consensus_repeat	Method
GGGTCCACCCCCGCACGTGCGGGGA	CRISPRCasFinder
CACCCCCGCACGTGCGGGGA	CRT
GACGGGTCCACCCCCGCACGTGCGGGGAACAGAC	PILER-CR

spacers of NC_020990_3

>3.1|1220722|36|NC_020990|CRISPRCasFinder
GCAGATGGCCGAGGCGCACGGGATGCCCGTCCTCAT
>3.2|1220783|36|NC_020990|CRISPRCasFinder
GCAGACCCACCCGGGGTCGTCGAGCAGCCGCTCGCC
>3.3|1220844|36|NC_020990|CRISPRCasFinder
ACAGGCACCGGCTGTGCTGTTGTAGAGGCTGAGGAG
>3.4|1220722|41|NC_020990|CRT
GCAGATGGCCGAGGCGCACGGGATGCCCGTCCTCATGGGTC
>3.5|1220783|41|NC_020990|CRT
GCAGACCCACCCGGGGTCGTCGAGCAGCCGCTCGCCGGGTC
>3.6|1220844|41|NC_020990|CRT
ACAGGCACCGGCTGTGCTGTTGTAGAGGCTGAGGAGGGGTG
>3.7|1220789|27|NC_020990|PILER-CR
CCACCCGGGGTCGTCGAGCAGCCGCTC
>3.8|1220850|27|NC_020990|PILER-CR
ACCGGCTGTGCTGTTGTAGAGGCTGAG

CRISPR arrays and Neighbor proteins around NC_020990_3

CRISPR arrays

The CRISPR arrays of NC_020990_3

>merge|NC_020990|3|1220697-1220910|CRISPRCasFinder,CRT,PILER-CR
AGGCTCGCCCCCGCACTCGCGGGGAGCAGATGGCCGAGGCGCACGGGATGCCCGTCCTCATGGGTCCACCCCCGCACGTGCGGGGAGCAGACCCACCCGGGGTCGTCGAGCAGCCGCTCGCCGGGTCCACCCCCGCACGTGCGGGGAACAGGCACCGGCTGTGCTGTTGTAGAGGCTGAGGAGGGGTGCACCCCCGCACGTGCGGGGAACAGTC

>NC_020990|3|3|1220697-1220904|CRISPRCasFinder
AGGCTCGCCCCCGCACTCGCGGGGA	GCAGATGGCCGAGGCGCACGGGATGCCCGTCCTCAT
GGGTCCACCCCCGCACGTGCGGGGA	GCAGACCCACCCGGGGTCGTCGAGCAGCCGCTCGCC
GGGTCCACCCCCGCACGTGCGGGGA	ACAGGCACCGGCTGTGCTGTTGTAGAGGCTGAGGAG
GGGTGCACCCCCGCACGTGCGGGGA

>NC_020990|3|1|1220702-1220904|CRT
CGCCCCCGCACTCGCGGGGA	GCAGATGGCCGAGGCGCACGGGATGCCCGTCCTCATGGGTC
CACCCCCGCACGTGCGGGGA	GCAGACCCACCCGGGGTCGTCGAGCAGCCGCTCGCCGGGTC
CACCCCCGCACGTGCGGGGA	ACAGGCACCGGCTGTGCTGTTGTAGAGGCTGAGGAGGGGTG
CACCCCCGCACGTGCGGGGA

>NC_020990|3|1|1220755-1220910|PILER-CR
CATGGGTCCACCCCCGCACGTGCGGGGAGCAGAC	CCACCCGGGGTCGTCGAGCAGCCGCTC
GCCGGGTCCACCCCCGCACGTGCGGGGAACAGGC	ACCGGCTGTGCTGTTGTAGAGGCTGAG
GAGGGGTGCACCCCCGCACGTGCGGGGAACAGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003951326.1|1214957_1216139_-|alkaline-phosphatase-family-protein	unknown	unknown	gnl|CDD|366747
NC_020990.1|WP_008406647.1|1207702_1208977_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_020990.1|WP_008406655.1|1213040_1213868_-|sulfurtransferase	unknown	unknown	gnl|CDD|225450
NC_020990.1|WP_003951327.1|1214113_1214914_+|VOC-family-protein	unknown	unknown	gnl|CDD|319911
NC_020990.1|WP_003951315.1|1226886_1229334_+|DNA-topoisomerase-IV-subunit-A	unknown	unknown	gnl|CDD|235503
NC_020990.1|WP_003951310.1|1234129_1235539_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270451
NC_020990.1|WP_015506978.1|1221846_1222533_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NC_020990.1|WP_003951314.1|1229415_1230534_-|GTP-binding-protein	unknown	unknown	gnl|CDD|223597
NC_020990.1|WP_015506977.1|1216810_1219690_-|bifunctional-GNAT-family-N-acetyltransferase/acetate--CoA-ligase-family-protein	unknown	unknown	gnl|CDD|131764
NC_020990.1|WP_003951311.1|1233164_1234127_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_020990.1|WP_015506976.1|1210272_1211457_-|hypothetical-protein	unknown	unknown	gnl|CDD|223039
NC_020990.1|WP_003951317.1|1223940_1225332_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_020990.1|WP_010641667.1|1219819_1220119_+|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|273389
NC_020990.1|WP_003951331.1|1208903_1210253_+|FAD-binding-protein	unknown	unknown	gnl|CDD|281959
NC_020990.1|WP_003951318.1|1222755_1223529_-|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NC_020990.1|WP_015506979.1|1225324_1226689_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_020990.1|WP_003951313.1|1230645_1232241_-|glycoside-hydrolase-family-13-protein	unknown	unknown	gnl|CDD|200471
NC_020990.1|WP_008406653.1|1211934_1212969_+|DUF3071-domain-containing-protein	unknown	unknown	gnl|CDD|378619
NC_020990.1|WP_003951312.1|1232278_1233154_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_020990.1|WP_003951325.1|1216138_1216738_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003951326.1|1214957_1216139_-|alkaline-phosphatase-family-protein	gnl|CDD|366747	pfam01663, Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars. Also in this family is ATX an autotaxin, tumor cell motility-stimulating protein which exhibits type I phosphodiesterases activity. The alignment encompasses the active site. Also present with in this family is 60-kDa Ca2+-ATPase form F. odoratum.	6.66474e-40
NC_020990.1|WP_008406647.1|1207702_1208977_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.43622e-19
NC_020990.1|WP_008406655.1|1213040_1213868_-|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	1.08998e-81
NC_020990.1|WP_003951327.1|1214113_1214914_+|VOC-family-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	1.10493e-30
NC_020990.1|WP_003951315.1|1226886_1229334_+|DNA-topoisomerase-IV-subunit-A	gnl|CDD|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0
NC_020990.1|WP_015506978.1|1221846_1222533_-|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	2.12214e-41
NC_020990.1|WP_003951314.1|1229415_1230534_-|GTP-binding-protein	gnl|CDD|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	1.56787e-65
NC_020990.1|WP_015506977.1|1216810_1219690_-|bifunctional-GNAT-family-N-acetyltransferase/acetate--CoA-ligase-family-protein	gnl|CDD|131764	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain. Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.	4.26976e-105
NC_020990.1|WP_003951311.1|1233164_1234127_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.20156e-74
NC_020990.1|WP_015506976.1|1210272_1211457_-|hypothetical-protein	gnl|CDD|223039	PHA03307, PHA03307, transcriptional regulator ICP4; Provisional.	9.68209e-05
NC_020990.1|WP_003951317.1|1223940_1225332_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	6.13683e-60
NC_020990.1|WP_010641667.1|1219819_1220119_+|HPr-family-phosphocarrier-protein	gnl|CDD|273389	TIGR01003, Phosphocarrier_protein_HPr, Phosphotransferase System HPr (HPr) Family. The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS].	9.8743e-22
NC_020990.1|WP_003951331.1|1208903_1210253_+|FAD-binding-protein	gnl|CDD|281959	pfam04030, ALO, D-arabinono-1,4-lactone oxidase. This domain is specific to D-arabinono-1,4-lactone oxidase EC:1.1.3.-, which is involved in the final step of the D-erythroascorbic acid biosynthesis pathway.	6.30972e-116
NC_020990.1|WP_003951318.1|1222755_1223529_-|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	3.28848e-36
NC_020990.1|WP_015506979.1|1225324_1226689_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	4.33401e-74
NC_020990.1|WP_003951313.1|1230645_1232241_-|glycoside-hydrolase-family-13-protein	gnl|CDD|200471	cd11332, AmyAc_OligoGlu_TS, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomaltooligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. Trehalose synthase (EC 5.4.99.16) catalyzes the isomerization of maltose to produce trehalulose. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NC_020990.1|WP_008406653.1|1211934_1212969_+|DUF3071-domain-containing-protein	gnl|CDD|378619	pfam11268, DUF3071, Protein of unknown function (DUF3071). Some members in this family of proteins are annotated as DNA-binding proteins however this cannot be confirmed. Currently no function is known.	3.71985e-61
NC_020990.1|WP_003951312.1|1232278_1233154_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	8.87658e-65
NC_020990.1|WP_003951310.1|1234129_1235539_-|extracellular-solute-binding-protein	gnl|CDD|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.59923e-45

Protein sequences

>NC_020990.1|WP_010641667.1|1219819_1220119_+|HPr-family-phosphocarrier-protein
MKGSFNMAERRVNVGWAEGLHARPASIFVRAATASGIPVTIAKPDTAPVNAASMLAVLGLGVQGGEEIVLSADADGAEATLERLAKLVAEGLDELPETV
>NC_020990.1|WP_015506977.1|1216810_1219690_-|bifunctional-GNAT-family-N-acetyltransferase/acetate--CoA-ligase-family-protein
MDTPSDQHAYPAHWEADVVLRDGGTARIRPITADDADRLVSFYEQVSDESKYYRFFAPYPRLSAKDVRRFTHHDHVDRVGLAVTIGGEFIATVRYDRIDDRGMPASAPADEAEVAFLVQDAHQGRGVASALLEHIAAVARERGIRRFTAEVLPANTKMIKVFTDAGYQQKRSFEDGVVRLEFGLEPTDRSLAVQHAREQRAEARSVQRLLAPGSVAVVGVGRTLGGVGRSILRNIREAGFTGPVHAVNQGFPDTGDTVEGVRAHRSVRDIAEPVDLAVIAVPAERVPEAVAECGEHGVQGLVVISAGYAEQGPEGRERQRALIRQARSYGMRVIGPNAFGVINTTPETRLNASLAPELPVPGRVGLFTQSGAIGIALLSALHRDGGGADGVPNPTGVSTFVSAGNRADVSGNDVMQYWYDDPHTDVALMYLETIGNPRKFTRLARRTAAAKPLVVVQGARHSGITPTGHPAPVTRLPYATVSALLRQAGVIRVDTVTELVDVGLLLAGQPLPAGPRVAILGNSESLGLLSYDACLSQGLRPLPPRDLTTDATPEDFRAALAAALADDGCDAVVVTAIPWVGADGVPERPDGEALGAALRTAHATAPDKPVVVVHVELGGLAEALSAAAGTGPGSPATQRGPAPSPAAPDSAAPAPDEAPPVPRTRRIPAYPAAERAVRALGEAVRYAQWRREAQRPGGVPEYESIDERGAAADITRLLAAAAPGEEGAAPRAHTLGAEDTRALLARYGIEVRPTLPAPDPDTAVRAAAELGYPVALKTTAPHLRHRADLGGVRLDLADEAQLRQAYAELTGLFGTPAELRPVVQPMAPRGVDTVVRTVIDPAVGAVLTFGLAGAPSELLGDTAHRLVPVTDRDATAMVRSIRTAPLLFGWRGSAPVDTPALEELLQRVSRLVDDHPEVVDVQLEPVVVAPRGVSVLGASVRLAPPPARDDLGPRTLPAY
>NC_020990.1|WP_003951325.1|1216138_1216738_-|hypothetical-protein
MAKTGTTTQGLRAAIERSGYYPALVAEAVEAAVGGEPVASYLVHQETTFDANEVRRHVTVLVLTPTRFIVSHTDEQAADSGSPTALATTSTESVKTGRISSVVLSRVVANPESYTPGTLPREVVLTIGWGAVSRIDLEPAACGDPNCEADHGYTGSSTADDLSLRVSEAGDGPDTVRQALAFAQALSEATAATATPAGR
>NC_020990.1|WP_003951326.1|1214957_1216139_-|alkaline-phosphatase-family-protein
MPSSAWPEPLPLASAPVPAYGSGSLADLLPTLAAGSGVPGMTATLTELPPADRNCVFLIDGLGWHQLLAHPAEAPFLSSLIATSRGGTGQPLTAGFPATTATSLASVGTGRTPGEHGLPGYTALNPDSGELMNQLRWKPWTDPHAWQPHPTVFSLADAAGVHTAQVSAPGFHHTPLTQVALSGGTFHGRLSGEERMDLAAAQLAAGDRALVYTYYSEVDGKGHRFGVDSDAWRGQLMYVDGLARRLAEQLPPRSALYITADHGMVDIPFDDRHRFDVDEDWELNAGIRLLGGEGRARHLYAVPGAARDVRTVWREVLGEQCWVAGRDEAIEAGWFGPHVEKRVRDRLGDVIVAARDDVAITATRREPNESALTGMHGSMTPAEQLVPLLEVRT
>NC_020990.1|WP_003951327.1|1214113_1214914_+|VOC-family-protein
MSVVRGQTVDQRTERPVPGTPCWVSLMADDPVASQEFYGRLFGWEFRPGPEQLGPYARALLDGRVVAGIGRMPEGQSLPVAWTPYLAADDVDETAGTVRHCGGTVGVGPLDAEEAGRMALAADPSGATFGIWQGREHRGAAVEGVPGSVLWNELVTRETAGVLPFYRAAFGFEAEREEAAEDAATLLLDGRPVASVLGVGQALGELGAAHWHTHFAVEDPDETVNRVIELGGRVQRPPRDGSHGRTATVADPWGAVFTVARPDTRA
>NC_020990.1|WP_008406655.1|1213040_1213868_-|sulfurtransferase
MNAIISATALAGELQGPRPPVLLDVRWQLGGPDQRPAYLAGHLPGAVHVDLDGELAGGPGKGGRHPLPDVEAFGAAMRAAGVDAGRPVVTYDGGQGWAAARAWWLLRWAGHPEVRVLDGGLAAWDGPLEEGEVTPEPGDFTPEPGRLELLDADGAAALAASGVLLDARAAERYRGDVEPIDRVGGHIPGAVSAPTTENTGEDGRLLPAAELAGRFAALGANPGRKVGVYCGSGVSGAHEVLALAVAGVDAALYVGSWSDWSADPDRPVATGPQPG
>NC_020990.1|WP_008406653.1|1211934_1212969_+|DUF3071-domain-containing-protein
MPELRVVAVSNDGTRLVLKAADSTEYTLPIDERLRAAVRGDRPRLGQIEIEVESHLRPRDIQARIRAGASAEEVASLAGIPVDRVRRFEGPVLAERAFMAERARKTPVRRPGENTGPQLGEAVRERLLLRGADRDTVQWDSWRRDDGTWEVLLVYGVAGERHSASWSYDPPRRLVQAVDDEARSLIGESDDVSAPEPSFPFVPRIARLPRERPERPERGPHAVEPETEELPATAEQGGRDSLTSLLEAVPSFRGDMVVPERPAAERPLEEPEQEQEAEEPPAPAASAGSAYADVLMPRAVAAHRDRLIGSTDRQAEADGVRPGRRAAVPSWDEIVFGTRRKNKE
>NC_020990.1|WP_015506976.1|1210272_1211457_-|hypothetical-protein
MRETTQVKEVGTRSGEEPQEEAKRIDLSVPQVAGSAVAAVAGAVAASQLGVYGTVIGAGVMSVVATTGGSVFQHLFRRTGEQIRDVAHVRPKGEPGPDVPDTFRADPEPDPLTDPAPGRVASADPATAHTVPGDPPAPVEATQLLGRIDPAAPRPADAEANQLLGQADPEATQLLSQADPGATQLLGQAGPDATRALRVPAADPAEADQATRLLRAVPEPSGPETGEFGEATTHQARTGRWKRPLISAAAVFVLAMGGITGWELVSGHALSGDSGPTISHLTGNRSQPSGDQEEEKAPAPEETPSGEAPSDGGSGTPSTQDPEDGTSSTGTPEEGTSPAPTRPGQQPGTPDDSTGDRSPTPTPTPSAGEPEQPTGQPSGGVPSGAAPEEGAPAG
>NC_020990.1|WP_003951331.1|1208903_1210253_+|FAD-binding-protein
MDEQQTQGSTRTASPVRTRNGTWRNWAGTVAARPARETVPASAAELAGAVRDAAARGMRVKAVGTGHSFTAAAATDGLLIRPDLLTGIQIDHEAGTVTVAAGTPLKRLNVALAREGLSLTNMGDIMEQTVAGATSTGTHGTGRASASLSAQITALELVTADGSLLSCSREQNPELFAAARIGLGALGVITSLTFAVEPVFLLRAREEPMGFDQVTAEFDQLVAENEHFEFYWFPHTGNCSTKRNNRTPGPAAPVGRLSGWFEDEFLSNGVFQAANTLGRAVPATIPSLARLSSRALSARTYTDIPYKVFTSPRRVRFVEMEYAVPREALVPALRELRAMVDRSPLRVSFPVEVRTAPADDIALSTASGRETAYIAVHLYKGTPYQAYFTAAERIFTAHEGRPHWGKIHTRDAEYFAEVYPRFAEFTALRDRLDPDRLFGNDYLRRVLGD
>NC_020990.1|WP_008406647.1|1207702_1208977_+|MFS-transporter
MPSPYRAIFSAPGSRGFSAAGFVGRLPLSMMGIGIVTMISQLTGRYGLAGALSAMVALSAALIGPQISRLVDLHGQRRVLRPATLVALAAVSGLLLSAQFSLPDWTLFLFAAGIGAVPSIGSMVRARWAALYRDQPRQLHTAYSFESVVDEACFIFGPIVSIGLSTTWFPEAGPLLAAVFLAAGVFSLTAQRSTEPVPHPREHHTKGSALRSTGLQVLVGTFVATGAIFGAIDVVTVAFAEEQGHKGAASLVLATYAAGSCLAGVVFGLLHFGGAPARRWLLGVVAMGVSMIPLQLVGNLPFLAVALFVAGLCIAPTMITTMALVEQHVPRAKLTEGMTWVSTGLAVGVALGSSVSGWVIDAAGAKAGYWVPAAAGAAAVLVGFLGYRRLSSPAPQREGPDGRAADAGQHQDGESGTHQERDLA
>NC_020990.1|WP_015506978.1|1221846_1222533_-|GntR-family-transcriptional-regulator
MGIPAQSVCTAIREDIVSGVHERGSRLTEEQLARRYGVSRVPVREALRTLEAEGFVVTRRHAGACVAEPTEQEAADLLEIRMLLEPLGAARAARRRTEAHLKVLRGLVRLGQERARLGEGEDLRSLGAWFHETLAQASGSPGLTALLTQLRQKVTWMYAVDPPAAPAESWAEHGAIVDAVARGDAERARALTAQHAERATAVHRLRFGSRTTGVRTSQHVVNIPGGRN
>NC_020990.1|WP_003951318.1|1222755_1223529_-|M23-family-metallopeptidase
MAFTRPTGKHRRPTRRATRTGAGLAGVAALTTTGVVSTLASPAAAAEAPAHTGFTEAIVIGHSLADRIDDQAAAQRLAAEDAAAEQAAVEAARLQAAEAKRKAEKKRAEKVRAARAAERERLNRYVLPVEGSYVSTGYQTGGSLWSSGSHSGVDFHAPAGSAVRAVGAGTVVETGWGGAYGNEVVIQMHDGTYTQYGHLASATVSVGQTVTPGQQIAVSGSTGNSTGPHLHFEARSGADYGTDMDPVAYLRGHGVDV
>NC_020990.1|WP_003951317.1|1223940_1225332_-|insulinase-family-protein
MSDVITPAMDLHPQPAGGAPRPWAFPAPERTTLDNGLTVLTCHRPGQQVVAVEVLLDSPLDTEPEGLDGLATIMARAFSEGTDRDSAEEFAAELERCGATLDAFADHPGVRLSLEVPVSRLEKALGLLADALRAPAFAEAEIERLVRNRLDEIPHEQANPARRAAKELSRQLFPAGSRVSRPRQGTEETVERIDAAAVRAFYERHVRPATATAVIVGDLEGTDLGALLAGSLGAWQGDAGQPNPVPPVTADDTGRVVIVDRPGAVQTQLLIGRVGPDRHDRVWPAQVLGTYSLGGTLTSRLDRVLREEKGYTYGVRSFAQVLRSTPEGTGAAMLAISGSVDTESTGPALDDLWKVLRTLAAEGLTDAELDTAVQNLVGVAPLKYETAAAVASTLADQVEQHLPDDFQARLYRMMTETGATEATAAVVSAFPADRLVTVLVGDASRIAEPVRALGIGEVSVVTG
>NC_020990.1|WP_015506979.1|1225324_1226689_-|insulinase-family-protein
MGDTATARAASGGLTATEHRLANGLRVVFSEDHLTPVAAVCLWYDVGSRHEVKGRTGLAHLFEHLMFQGSAQVKGNGHFELVQGAGGSLNGTTSFERTNYFETMPAHQLELALWLEADRMGTLLTALDDESMENQRDVVKNERRQRYDNVPYGTAFEKLTALAYPEGHPYHHTPIGSMADLDAATLEDAREFFRTYYAPNNAVLSVVGDIDPGQTLAWIEKYFGSIPGHEGKRPPRDGSLPDTIGSELREVVREEVPARALMAAYRLPEDGTRAADAADVALTVLGGGESSRLYNRLVRRDRSAVAAGFGLLRLAGAPSLGWLDVKASGDVEIPAIETAVDEELARFAAEGPTAEEMERAQAQLEREWLDRLGTVAGRADELCRHAVLFGDPQLALTAVGRVLDVTADEVRQAAAERLRPDNRAVLVYEPLTAEEAGPADQTDTATGEEAAASE
>NC_020990.1|WP_003951315.1|1226886_1229334_+|DNA-topoisomerase-IV-subunit-A
MARRSTKTPPPDDFEERILDIDVVDEMQGSFLEYAYSVIYSRALPDARDGMKPVHRRIVYQMNEMGLRRDRGYVKCARVVGEVMGKLHPHGDASIYDALVRMAQPFSMRLPLVDGHGNFGSLGNDDPPAAMRYTECRMADATSLMTESIDENTVDFSPNYDGQEQEPVALPAAFPNLLVNGASGIAVGMATNMPPHNLGEVVAAARHLIKHPGADLETLMRFVPGPDLPTGGRIVGLGGVRDAYATGRGTFKIRATVAVENVTARRKGLVVTELPFSVGPEKVISKIKDLVGAKKLQGIADVKDLTDREHGLRLVIEIKNGFVPEAVLEQLYKLTPMEESFGINNVALVDGQPLTLGLKELLEVYLDHRFTVVRRRSEFRRGKKRDRLHLVEGLLVALVDIDEVIRIIRDSENSAEARERLMERFSLSDIQTQYILDTPLRRLTRFDRIELESERDRLTAEIEELSRILDSDAELRKLVSSELAAVSKKYGTDRRTVLLESSGAAAAVPLQVEDTPCRVLLSSTGLLARTADATPLAEAPKRVKHDLIVSAVAATARGEVGAVTSAGRLLRLQVIDLPQLPGTDTAPSLSGGAPVAEFLTLEADERLVCLTTLDESSPGLALGTAQGVVKRVVPDYPAHKEELEVISLRDGDRIVGATELRTGEEDLVFITDEAHLLRFPASVVRPQGRPAGGMAGVKLGEGARVVSFTAVDPAVDAVVFTVAGSRGTLDDSVQTTAKVTPFDQYPRKGRATGGVRCQRFLKGEDCLSFAWAGPAPAHAAQRDGSPAPLPELDPRRDGSGLSLPKPVAAAAGPVG
>NC_020990.1|WP_003951314.1|1229415_1230534_-|GTP-binding-protein
MGRQQIPVVVLAGFLGSGKTTLLNQLLWRSRGTRIGAVVNDFGAIEIDAMTVAGQVGSTVSLGNGCLCCAVDVAELDTYLERLTRPEAGLDVIVIEASGLAEPVELVRMILASENPHIRYGGLVEVVDAAEYEATRERHPELDRHLAAADLVVLNKTDRVTPAELAELLTAVRARAGDGAVTPASYGRIDPELLFDRRPQTERYGQLSFDDAREEDEPGGGCEDHDDHDGHLHAAYDSASFTTGTPLHPRRLMDLLDGRPEGLYRIKGFVDFGPLDPGHVYTLHAVGRFLRFAPRPWEPGEERRTQLVLIGAGIDPDALTAQLEGCRDAAREAEERHLWSVLRFVRAEEDTADPDDPEALRAAAPGTEQPVA
>NC_020990.1|WP_003951313.1|1230645_1232241_-|glycoside-hydrolase-family-13-protein
MPDSDWWRSAVIYQVYVRSFADADGDGTGDLAGVRAKLPYLAQLGVDALWFNPWYASPMADGGYDVADYRAIHPSFGTLAEAEKLIEEAAGHGIRTIVDIVPNHVSEAHPWFRAALAEGPGGPSRDLFHFRPGRGEHGELAPNDWQSEFGGPAWTRLPDGEWYLHLFAPEQPDLNWAHPAVRTEHEEILRFWFERGVAGVRIDSAALPAKDPALPDFTPGQDPHPYLDRDELHDIYRSWRAVADRYGAVFVGEVWLPDSERFARYLRPDELHTAFNFAFLSCPWEPERLRAAIRDTLAEHAPVGAPATWVLCNHDITRTVTRYGRAETGFDFAAKRFGTPTDPALGTRRARAAALLSLALPGATYLYQGEELGLPEAEIPREHIEDPMHARSGGVDPGRDGCRVPLPWTADAPHAGFSTGEPWLPQPPGWAAHAADLQDGDPASMLTLYRTALALRRATPGLGDGPLEWLESPEEVLAFRRPGGVLCLVNLGAGPVPVPEGTELLLASGALGADGALPSDTAVWLREPAAA
>NC_020990.1|WP_003951312.1|1232278_1233154_-|carbohydrate-ABC-transporter-permease
MTTRTLISPARLSRPRGRILYWTVLFLVVAVFTLVFIGPLYWMVTSGLKDTEEFARIPPTLVPDAVHPGNYGEAWQVMELSQLLFNTLYYAFGALAFQLVLDVAAAYSLSKLRPVLGKAILGAMLVTLMIPATVLVVPQYLTVLDLPVFERNLLNTPWVIWLPSVTNAFNIFLLKRFFDSIPRELLDAAAIDGASPMRTLRSVVLPISRPILGVVSIFAVVGVWKDFLWPMLALPDPGKQTLNVGIYSLASGVPENWLLAALAMASLPTLILFLIFQRNIMSGLTAGGLKG
>NC_020990.1|WP_003951311.1|1233164_1234127_-|sugar-ABC-transporter-permease
MAPPTPTPTLTRRPAGTDDGAPRVKEPRRGAFARAVRRNLTAHAFLIGAVLCFGFFSWYPMVREVVLAFQKTENGVVSWAGWSNFVYVFNDPDFALAWRNTALFTLLALLLGFVVPFVIALVLNEFRHARGYLRLLVYLPVMLPPVASVLLFKYFYDPGHGLFNRLLELFGLPAQQWLQSSDTAMLSLVIASTWMNMGGACLIYLAALQTIPGELYEAAELDGAGLLRKIWHVTIPQTRLILSLLFLMQIIATMQVFTEPFLLTGGAGPEGSTTTVVHLIYQYAFNFNNYGAAAALGLVLLVVLAGFSAAYVRLNRAEQE
>NC_020990.1|WP_003951310.1|1234129_1235539_-|extracellular-solute-binding-protein
MRSSGFSTPRRRRTAVTFVSALTLLSLAACGTSSSGDQDPAPGGSADAATPLDPKTKLTLTIDCMPPAAKKAELKQWKEDVATFNKTYPNITIDGRSTPGQCLEPPRFTAMLKAKSQPDVFYAYFTDLDQVLDNDGAADISAYVNEKTVPALADIDPDVMKVLKKDDKLYALPTSNYRMGLLINRGLFEKAGLDPDTPPSTWEEVREAADKIAGLGKGIAGFGEYSAGNTGGWHYTATVYGEGGEIVGPDGKAAFNDATGKRVAQNLYDMRWKDDSMGKTQLLKWGDLQKQMATDKLGMFLAAPDDITYMVQQLGADYANFGMGPMPGQKATLFGGNSYMIKKGISSDKIKAAVAWLDLKTLSPGKGQFAWSRTKADGLPVGLPQPAFFTGAAKEKDDKERADHATMPVENFRAFTDNPVDGKAEPPKAQEVYKVLDTVMSTLLTNKDADIDKLLDTAEQQVNQVLANQ

Crispr_ID: NC_020990_4

• CRISPR_ID: NC_020990_4
• CRISPR_location: 1593815-1593916
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_4

Consensus_repeat	Method
CCAGCCCGGCCGGCGTTTGAGGCC	CRISPRCasFinder

spacers of NC_020990_4

>4.1|1593839|54|NC_020990|CRISPRCasFinder
ATCGGTGACCGCCACGGACGACCACCGGCACCGCAGACCGAAGCCCGGCCACAA

CRISPR arrays and Neighbor proteins around NC_020990_4

CRISPR arrays

The CRISPR arrays of NC_020990_4

>merge|NC_020990|4|1593815-1593916|CRISPRCasFinder
CCAGCCCGGCCGGCGTTTGAGGCCATCGGTGACCGCCACGGACGACCACCGGCACCGCAGACCGAAGCCCGGCCACAACCAGCCCGGCCGGCGCTTGAGGCC

>NC_020990|4|4|1593815-1593916|CRISPRCasFinder
CCAGCCCGGCCGGCGTTTGAGGCC	ATCGGTGACCGCCACGGACGACCACCGGCACCGCAGACCGAAGCCCGGCCACAA
CCAGCCCGGCCGGCGCTTGAGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_008410677.1|1591604_1591844_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507067.1|1587544_1589779_-|MMPL-family-transporter	unknown	unknown	gnl|CDD|225272
NC_020990.1|WP_003951005.1|1600400_1600949_-|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl|CDD|367590
NC_020990.1|WP_003951012.1|1591840_1593337_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl|CDD|234572
NC_020990.1|WP_015507070.1|1601452_1602229_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_020990.1|WP_008410671.1|1598581_1599595_-|methionine-synthase	unknown	unknown	gnl|CDD|239426
NC_020990.1|WP_003951016.1|1586891_1587509_-|hypothetical-protein	unknown	unknown	gnl|CDD|377085
NC_020990.1|WP_003951017.1|1586511_1586823_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003951003.1|1602273_1603419_-|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl|CDD|234664
NC_020990.1|WP_015507065.1|1582860_1585998_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|226415
NC_020990.1|WP_015507068.1|1593978_1596147_-|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NC_020990.1|WP_037630071.1|1579450_1580572_+|glucose-sorbosone-dehydrogenase	unknown	unknown	gnl|CDD|369642
NC_020990.1|WP_003951011.1|1593342_1593639_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl|CDD|178810
NC_020990.1|WP_003951002.1|1603480_1604215_+|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NC_020990.1|WP_003951014.1|1590078_1591587_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl|CDD|235489
NC_020990.1|WP_003951021.1|1581336_1581708_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507069.1|1596374_1598561_-|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl|CDD|236137
NC_020990.1|WP_008410664.1|1601034_1601397_+|DUF427-domain-containing-protein	unknown	unknown	gnl|CDD|377265
NC_020990.1|WP_008410668.1|1599676_1600375_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|181298
NC_020990.1|WP_003951001.1|1604237_1605407_-|cysteine-desulfurase	unknown	unknown	gnl|CDD|224029

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003951014.1|1590078_1591587_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl|CDD|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NC_020990.1|WP_015507067.1|1587544_1589779_-|MMPL-family-transporter	gnl|CDD|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	3.64834e-92
NC_020990.1|WP_003951012.1|1591840_1593337_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl|CDD|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
NC_020990.1|WP_015507070.1|1601452_1602229_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.3424e-11
NC_020990.1|WP_008410671.1|1598581_1599595_-|methionine-synthase	gnl|CDD|239426	cd03310, CIMS_like, CIMS - Cobalamine-independent methonine synthase, or MetE. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme catalyses the last step in the production of methionine by transferring a methyl group from 5-methyltetrahydrofolate to L-homocysteine without using an intermediate methyl carrier. The active enzyme has a dual (beta-alpha)8-barrel structure, and this model covers both the N-and C-terminal barrel, and some single-barrel sequences, mostly from Archaea. It is assumed that the homologous N-terminal barrel has evolved from the C-terminus via gene duplication and has subsequently lost binding sites, and it seems as if the two barrels forming the active enzyme may sometimes reside on different polypeptides. The C-terminal domain incorporates the Zinc ion, which binds and activates homocysteine. Side chains from both barrels contribute to the binding of the folate substrate.	3.47784e-62
NC_020990.1|WP_003951016.1|1586891_1587509_-|hypothetical-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	0.00301964
NC_020990.1|WP_003951005.1|1600400_1600949_-|TIGR00730-family-Rossman-fold-protein	gnl|CDD|367590	pfam03641, Lysine_decarbox, Possible lysine decarboxylase. The members of this family share a highly conserved motif PGGXGTXXE that is probably functionally important. This family includes proteins annotated as lysine decarboxylases, although the evidence for this is not clear.	1.53611e-38
NC_020990.1|WP_003951003.1|1602273_1603419_-|tRNA-2-thiouridine(34)-synthase-MnmA	gnl|CDD|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NC_020990.1|WP_015507065.1|1582860_1585998_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	7.08823e-38
NC_020990.1|WP_015507068.1|1593978_1596147_-|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	2.11688e-104
NC_020990.1|WP_015507069.1|1596374_1598561_-|NAD-dependent-DNA-ligase-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NC_020990.1|WP_003951011.1|1593342_1593639_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl|CDD|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	1.0549e-38
NC_020990.1|WP_003951002.1|1603480_1604215_+|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	5.8096e-32
NC_020990.1|WP_037630071.1|1579450_1580572_+|glucose-sorbosone-dehydrogenase	gnl|CDD|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	5.30086e-86
NC_020990.1|WP_008410664.1|1601034_1601397_+|DUF427-domain-containing-protein	gnl|CDD|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	1.39122e-42
NC_020990.1|WP_008410668.1|1599676_1600375_-|SDR-family-oxidoreductase	gnl|CDD|181298	PRK08219, PRK08219, SDR family oxidoreductase.	2.39264e-110
NC_020990.1|WP_003951001.1|1604237_1605407_-|cysteine-desulfurase	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	4.43932e-160

Protein sequences

>NC_020990.1|WP_003951011.1|1593342_1593639_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MPGITREEVAHLARLARLELKAEELEHFAGQLDDILGAVARVSEVAGQDVPPTSHPLPMTNVMRADEVRPSLTPEQALSGAPAQEQQRFKVPQILGED
>NC_020990.1|WP_003951012.1|1591840_1593337_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MSDSIIKLTAAETAAKIASGELTAVEVTEAHLARIEAVDEKVHAFLHVDREGALAQARAVDAKRAAGEKLGPLAGVPLALKDIFTTEGIPTTVGSKILEGWIPPYDATVTKRLKDADVVILGKTNMDEFAMGSSTENSAYGPTGNPWDLTRIPGGSGGGSSAALAAFEAPLAIGTDTGGSIRQPAAVTGTVGVKPTYGGVSRYGMVAFSSSLDQGGPCARTVLDAALLHEAIAGHDPLDSTSIDAPVPPVVEAARNGSVAGMRVGVVKQFRGEGYQAGVVQRFDESVELLRKLGATVVELDCPSFDLALSAYYLIAPSECSSNLARFDAMRYGLRVGDDGTRSAEEVTAITREEGFGDEVKRRVILGTYALSSGYYDAYYGSAQKVRTLITRDFERAFEEVDVIVSPTTPTTAFPIGERADDPMAMYLADLCTIPTNLAGNAAMSLPCGLAPEDGLPVGLQIIAPAMKDDRLYKVGAAVEAAFVEQWGHPLLEEAPSL
>NC_020990.1|WP_008410677.1|1591604_1591844_-|hypothetical-protein
MSALSKAKGFKKSKTGTYLSIGTTAFGALSVYKQMKAARHDHDTLSLVDAVATAAGIVTGVALLVRELKRLGDDDVLLG
>NC_020990.1|WP_003951014.1|1590078_1591587_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MTVTDLVPYDDALAAYDPVMGLEVHVELGTKTKMFCGCSTELGADANSQTCPTCLGLPGSLPVVNAVGVESAVKIGLALHCEIAEWCRFARKNYFYPDMPKNFQTSQYDEPIAFDGYLDVQLEDGEVFRVEIERAHMEEDTGKSTHVGGATGRIHGASHSLLDYNRAGIPLIEIVTKPIEGAGERAPEVAKAYVAELRELIKALGVSEARMEMGQMRCDVNLSLRPKGRQEFGTRSETKNVNSLRSVERAARFEIQRHAAVLSSGGTIVQETRHFHEEDGSTTAGRIKDNAEDYRYFPEPDLVPVAPPREWVEELRSTLPELPRVRRNRLREEWGVSEHDMQSILNAGAIGPIVATIEAGADAAAARKWWMGELARNANETGRPLEGLPITPAQVARVAELVKGGDLNDKLARQVIEGVLAGEGDPDTVVEKRGLKVVSDEGALTTAVEEAIAGNPAIADKIRGGKVAAAGALVGAVMKATRGQADAARVKELILAQLGVEG
>NC_020990.1|WP_015507067.1|1587544_1589779_-|MMPL-family-transporter
MAALARWCMHHRLLAVLLWLLVLGGAGTAAGLAGSAYTNDYAAGGTESGEATALIERGFPGLAGDSDTVVWHAPDSSVRAADVEQTMTHALDRIADLPGVASVAGPYAEAGTGPGGGISEDGRTAYATVTFAAQTSDISPAQAQAVVDAAHGADGDGLQVEVGGSAVALTEAPALHTAELIGVAVAAVVLFLAFGSLAASLLPIATALVSVGIAYAGIVLLGHVMTVADFAPMLGMLIGLGVGIDYALFIVTRHRTGLKQGLTVDAAAARAVATTGRAVVFAGATVCIALLGMLILRLEFLNGVAIAASLTVLLTVAASLTLLPALLAYIGPRALSRRERRRLAAEGPLPELPTGFAARWSRFVERHPKLLGVLATAVMAVLALPMLTLHLGTSDQGNNPASSTTRQAYDLLADEFGPGVNGPLTLVTEVGGAPDRLALDGLEQTLRQTEGVAGVTPVVFNDASDTALLTVVPTSSPQSEQTSALVDRLRADVLPRAEAGTGLDLKVGGMTAAYDDFAELIVGKLPLFIGVVIGLGFALLLLAFRSVGIPLKAALMNVMAVAGAFGVVVAIFQWGWGSELLGLGSSGPIEPFLPVIMVSVLFGLSMDYQVFLVSRMHEEWVATGDNTRAVRVGLAETGRVINSAAVIMISVFLAFVLSGDRLIAMFGIALAVAVALDAFVLRTLLVPALMHLLGRANWWLPGWLDRVLPRISIEGPPEQRAAHPAEVPVPRAPDEDPARSAALR
>NC_020990.1|WP_003951016.1|1586891_1587509_-|hypothetical-protein
MDTKTADGKRPATGAEDEQQDTDGTTPGKTPGEEKDPAGKGAPAAAETDGDAVVHDADDLDADDEAATEDTATAAPTGIAAGAAAIVSVVLGVVSLTGGWLGTIASARASLIGQLETSQGAGVADQVQAIYGDSWEAAALVGGAFAAVGLLVGIGVVLRVAYWPARTGPVWVRSAAWAGVAVGLVGLLLALSKYTGLLLGVPSAG
>NC_020990.1|WP_003951017.1|1586511_1586823_+|hypothetical-protein
MSRLPAACLHTHLFRGARVLVDGLADPSGYARAPRPLELALRFSDDAPADAEVLVSPESGETVLAVGAYTTEAGTSLSSRTWLVGGVEARDAGVELTIGVRVG
>NC_020990.1|WP_015507065.1|1582860_1585998_-|helix-turn-helix-transcriptional-regulator
MLTDVEHKSVSPVFVGRATELDTLRRALTEVRTGEPRALLIGGEAGVGKTRLLEEFTAEATGDGALVTLGACVESGTEGLPFAPFAAVLRTLRRLLPEEFAAGAAGQEGELARLLPDLGEAALARSGEEGTARLFDLTARLLEHLAAARPVVLVVEDLHWADASTRRLIAYLFRTLRTGRLLVLASYRADDIHRRHPLRPLLAELDRLRTVQRLELPRFNRAEVAGQLAGILAAEPDDSTVDEVFARSEGNAFFVEELTVAARSGCHAGLTDSLRDLLLVRVEALPERSQHLVRLAAEAGPTTEYALLAAVARLPETDLLDALRAAVGAHILLPSEDGDGYRFRHALVREAVTDDLLPGERTRIGRQFAEALAADPTLVAPDAYATRLAGYWYRAHDAAKALPAVLRAAAEARHRHAYAEQFTLLERAMELWDGVPEEIRGALRSADHAEVYPHLTARRGPGTGEGPGAPLRYLHLMADAAVAGRLCGQRERAYKIAKKAVRMLGETRSTGETWDEPLFAAWFWVQRSRVAESVGRGDGWQELHTAQELVRGLPPSEMHAEVLSCVASWWMLHRPGPEAYAAAERAVQYARMVGADDDVELAARGTLAGLRIDSGDIDTGLAELREVLADALRRERPHQIGRCYVNLPSHLEGIGRSAEAAALIERGLKESDRYGLLFTATFLHANHAESLISLGRWDEALRSADAAAGLTGQAKPAGMAAHSRTVIALARGDLDTAVRQDAVARSRVGSHGAMPQHALPLATARLSIAAAEGRVHDARAELRAAAETGFPPGTQRYAWPLLVAAATTESDARGLPGAEEGRADHIALVRRLAKNLVTFVPVCEAQAAWVRAELRRGEGQDTVEDWADVHQRFLPLERPWNLARVALRYAEALLADSGTRPGPGRTQAAELLRTARATARRLGARPLADSIDLLARRARLSLSTRPAATPRPDTPTDPAEALGLTRREREVLSLLVAGRTNRHIAEELFISPKTASVHVSHILAKLEVSSRGEAAAVAHRLRLVGSGAGGSGGEGGREKGVGVGA
>NC_020990.1|WP_003951021.1|1581336_1581708_-|hypothetical-protein
MLTATRVDSEGKATVAAQYYGADSENGDRIDDPSEDALFMMISDLNDSDNTFVVVQPDEDDPVWFASVAVLDEGGYETVRRDTTRNEHEVTTATSVNDIARDLTIWMAARDFPGRPTSQVSES
>NC_020990.1|WP_037630071.1|1579450_1580572_+|glucose-sorbosone-dehydrogenase
MALLGAGCSSGPAEPESGPSSPGSASPSGSGSPSAASDAPPDKGSVEVVRTLATGLKSPWGLAPLPDGNLLVASRDEGEIVQVDGDSGKTSEAGQVPGVDAEGEGGLLGLALSPDFATDQLVYAYFTTASDNRIASMRYDAKKPAGERLSAPSTIFKGIPKGFTHNGGRIAFGPDKMLYVGTGETGDKGLAQDKESLGGKILRMTPEGEPARGNPDEDSVVWSYGHRNVQGLAWDEDRRLWASEFGQDTWDELNHIEKDGNYGWPDVEGEGDGDGDFRNPVEQWRTADASPSGIAVAEGSVWMAGLRGERLWRIPLSGDKPSAKPQAFLEGEYGRLRTVVSAGGDKLWVVTNETDGRGSPEKDDDRILEVRVR
>NC_020990.1|WP_015507068.1|1593978_1596147_-|EAL-domain-containing-protein
MEPTESAAPASWPRLRRTIAARTGPRRAPHAPGHAEGVTPLLPIAVIALAAVLLATGIGRAVATGHALFPAGAAGWALAVLTGIVVGHLVALGRDRWWGGTGSGAALTLAVLLLYGWVPAGLVSITVVVLVGVARRHRWRQGLLHGAVDILGIAAAALLLTLTGVTPSVETPWDPRSWTLATGTGVLFAATGYLLMTRLLLWLVHTPNPGTLPTVTRTAVIRQSLVGVALLGIAPLICVVAVALPVLLPLFSIPLIALDSTLWIARARAEEQLRDPLTGLPNRQWLLERIWTALDEAEQAGTRSALLLIDLDRFRSVNDTLGHLAGDRLLLQIAERLRPALPRGAEAARLGGDEFAVLLPVADSTTAAQRVARRLVSELGSPLDLDGLTLVLEASAGVAVYPDHAQDAEGLLRRADVAMYQAKRDRTGVEVYESKRDSNTPDRLGLLGDLRRALDAGEVELHYQPKVRFDGHVAGLEALVRWVHPERGRVPPDEFIAIAESSGLMPHLTEYVLETALGQVARWRAQGLNVPVAVNVSPRDVHSPGFAGAVAARLARHGVPAGALQLEITEHVLLEDPQRAADTLAGLTGHGVKMSLDDFGTGYSSLVHLRRLPVSELKIDRSFVARLAVDTEDAEIVRCTVDLAHSLGLLVVAEGVEDDETWERLRDLGCDAVQGWLVAAAMPAGETTAWLRARGARGWRRPAEIAAEAAEAGRAVRSGPPQ
>NC_020990.1|WP_015507069.1|1596374_1598561_-|NAD-dependent-DNA-ligase-LigA
MAGEQQNADVPADARERHKHLAEQVEEHRFRYYVNDQPVVSDAEFDRQLRALTQLEEQYPPLRTPDSPTQKVAGQYETEFTSVQHRERMLSLDNAFDDEELAAWAERVAKEVGAPGYHFLCELKVDGLAVNLTYEHGRLTRAATRGDGRVGEDITPNVRTISDIPERLHGDDLPALVEIRGEVFFPMEEFEKLNARLVEAGEKPFANPRNAAAGSLRQKDPRVTATRPLHMVVHGIGAREGFTIDCLSHAYDLLRSWGLPTARHNKVVEGLDGVRAFITYYGDHRHSVEHEIDGVVVKLDEVPLQGRLGSTSRAPRWAIAWKYPPEEVNSRLIDIRVGVGRTGRVTPYAQVEPVTVAGSEVEFATLHNQDVVRAKGVLIGDTVVLRKAGDVIPEILGPVADLRDGTERPFTMPAECPECSTPLKPMKEGDIDLRCPNARSCPAQLRERIYYLAGRKCLDIENFGYVAATALTQPLEPSEPPLRDEGDLFDLTVDQLLPIRSYVLDPDSGLPKRDPKTGEEKIVTFFANKQGEAKKNTLAMLDHIEAAKQRPLARVLTGLSIRHVGPVAAQALAREFRSIERIEAATEEELAQTEGVGPTIAASLKSWFAEEWHREIVRKWREAGVRMEEESTGEDEGPRPLEGLTVVVTGTLEHHTRDNAKEALQNQGAKVTGSVSKKTSFVVVGDNPGSKYDKAMQAKVPVLDEAGFAVLLDQGPDAAREVALPLPE
>NC_020990.1|WP_008410671.1|1598581_1599595_-|methionine-synthase
MSDTDDFPTLRATGIGSMPGGDAREAARTVTGTFAGGEGMPYLPELPARGPGADMTGRTAGLLADLHAQLEPSGWRIADRPGRDMRRAVSWLREDLDALEEYTQGYEGPLKLQVTGVWTLAAALQTRGGEAFLGDAGACRDLAASLAEGLRGHLAEVRRRVPGARLVLQLDEPSLTAVLTGTVRTASGYRTYRAVDRQVVESALREVAAVHDGPVLAHSCAPSVPFALLRRAGFAGASFDFSLLTEGDDEALGEGVEAGFRLLAGVVPGTDTALSDPAGSVMGVRTWWRRLGLNPGLLPEAVAITPSCGLAGASPGYARAALAHCVRAANSLADNPE
>NC_020990.1|WP_008410668.1|1599676_1600375_-|SDR-family-oxidoreductase
MRAMATHVITGAGSGIGAAVARRLHERGDHLVLVARDAGRARELAAAHPGAETLVADLADPDRISWALSHQTLPDRIDSLLHIAGVVDLGTVGELTPKTWRHQIDVNLLAPAELTRHFLPQLRLTHGHVVFVNSGAGLNANGGWAAYAAAKHGLKALADALRQEEQEHGVRVTSVYPGRTASAMQQKIHQQEGKEYDPDRWISPESVATTLLTALDLPADAVINDVSIRPGG
>NC_020990.1|WP_003951005.1|1600400_1600949_-|TIGR00730-family-Rossman-fold-protein
MNICVFLSAADLPERYTRPAREFAELLGKGGHTLVWGGSDKGLMKVVADGVEQSGGKLLGVSVEFLAASARPVPAESGEMIITADLAERKAQLLARADAVVIMVGGTGTLDEATEILELKKHGMHTKPVVLLNTAGFYDGLREQFQRMEDEGFLPLPLTELVLFAEEPVGALAHLEESAGVQ
>NC_020990.1|WP_008410664.1|1601034_1601397_+|DUF427-domain-containing-protein
MTQGHGDDTARGHRITVEQAPVHVRVVRDGQVVAESRRPLLLRETGLPVRYYLPPEDVRTDLLTPSETHTVCPFKGTASYWSLPGEPDLVWAYPEPIEAVAEIRDHFCFYETEVVAEPAG
>NC_020990.1|WP_015507070.1|1601452_1602229_+|alpha/beta-hydrolase
MDTVVSRDGTPIAYGTRGSGPALVLVGGAMTAGEHAAPLAGLLADSFTVVTYDRRGRGRSGDTRPYAVGREVEDLAEVIRAVGGPAALYGVSSGAALALHAASAGTAVSRVALYEPPFTVGEADPSRREAYRSRLVALLAADDRGGAVELFMTRIGLPPEMIAGARRSPAWPGLEAVAPTLAYDDELLGDGAPPLDRLALVPVPALVMAGSASPPAMTEAARTVAEALPEGRYRELGGQTHDVAPEAVAAALREFLLP
>NC_020990.1|WP_003951003.1|1602273_1603419_-|tRNA-2-thiouridine(34)-synthase-MnmA
MTETSPRTENPPRPLRVLAAMSGGVDSAVAAARAAEAGHDVTGVHLALSANPQSFRTGARGCCTIEDSRDARRAADVIGIPFYVWDLAERFREDVVEDFVAEYEAGRTPNPCLRCNEKIKFAALLDKALALGFDAVCTGHYATVVTREDGSRELHRASDMAKDQSYVLGVLDERQLAHALFPLGDTLTTKDEIRAEAERRGLAVAKKPDSHDICFIADGDTRGFLAGRLGTAEGDILDEAGQKVGTHEGAYGYTIGQRKGLRIGTPAADGKPRYVLDISPVDNTVTVGPAAALDVTGLTAIRPRWCGTPPEGSGRYTAQLRAHGEETPVTAEVREGELTVTFDEPVRGVAPGQAVVLYDGSRVVGSATIAATRRAGAVPAA
>NC_020990.1|WP_003951002.1|1603480_1604215_+|N-acetylmuramoyl-L-alanine-amidase
MGNGNHSAGAGRGADGGQGARRRTVRRRSVLIGAGVAAATGGVLAREELGRLWYQVPGVSKPRVEGAVDYAKAEWVAASDANWRRADRPDDFTVDRVIIHVVQGSYAVALKVFQDPAHRAATHYVVGKDGRVAQLIRELDVAYQAGNREYNERAVGIEHEGFVDRPQDFTGAMYESSARLTADICLRHGIPVDRTHVIGHVEVPGTDHTDPGPHWDWDRYLRLVRAAKKQLEREREQDERRERA
>NC_020990.1|WP_003951001.1|1604237_1605407_-|cysteine-desulfurase
MAYLDHAATTPMLPEAVEAMSAQLTRTGNASSLHAAGRRARRTAEEARETLAEALGARPSEVVITAGGTEADNLAVKGLYWARRAADPRRTRVLASPVEHHAVLDAVHWLGEHEGATVEYLPVDTLGRVHPEALREALARNPHDVALATVMWANNEIGTVQPVTELAAVAAEYEIPLHADAVQAFGQLPLEFGASGLAAATVSGHKIGGPYGIGALLLGRQYTPVPVLHGGGQERHVRSGTLDVPAIASFAVAGQLAAERRPRFAEEIGALRDELVAAVHAAVPDAILGGDPDPAGRLPANAHFTFPGCEGDSLLLLLDAQGIECSTGSACTAGVAQPSHVLLATGTPPDLARGTLRFSLGHTSTRADVEAVAKAIGPAVERARNAGLS

Crispr_ID: NC_020990_5

• CRISPR_ID: NC_020990_5
• CRISPR_location: 1722497-1722584
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_5

Consensus_repeat	Method
CAGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NC_020990_5

>5.1|1722521|40|NC_020990|CRISPRCasFinder
TCCGTGACCGCGAGGTCGGCACAGACCAGCACCCCTCGAT

CRISPR arrays and Neighbor proteins around NC_020990_5

CRISPR arrays

The CRISPR arrays of NC_020990_5

>merge|NC_020990|5|1722497-1722584|CRISPRCasFinder
CAGCCCGGCCGGCGCTTGAGGCCATCCGTGACCGCGAGGTCGGCACAGACCAGCACCCCTCGATCAGCCCGGCCGGCGCTTGAGGCCA

>NC_020990|5|5|1722497-1722584|CRISPRCasFinder
CAGCCCGGCCGGCGCTTGAGGCCA	TCCGTGACCGCGAGGTCGGCACAGACCAGCACCCCTCGAT
CAGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003950911.1|1709777_1710443_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_020990.1|WP_003950903.1|1720622_1721642_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213235
NC_020990.1|WP_003950896.1|1726369_1726762_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950892.1|1731365_1732214_-|3-hydroxyacyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|224170
NC_020990.1|WP_003950906.1|1714785_1715226_+|methylmalonyl-CoA-epimerase	unknown	unknown	gnl|CDD|213772
NC_020990.1|WP_015507092.1|1727895_1730313_-|ATP-binding-protein	unknown	unknown	gnl|CDD|223021
NC_020990.1|WP_030306364.1|1726965_1727637_+|endonuclease-NucS	unknown	unknown	gnl|CDD|235114
NC_020990.1|WP_003950904.1|1719559_1720498_+|cellulose-binding-protein	unknown	unknown	gnl|CDD|224117
NC_020990.1|WP_003950893.1|1730634_1730958_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_020990.1|WP_003950902.1|1721643_1722414_+|ABC-transporter-permease-subunit	unknown	unknown	unknown
NC_020990.1|WP_003950900.1|1723785_1724622_+|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|372253
NC_020990.1|WP_003950908.1|1712360_1713350_-|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl|CDD|224617
NC_020990.1|WP_008409336.1|1725240_1726275_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
NC_020990.1|WP_003950907.1|1713439_1714642_-|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|180261
NC_020990.1|WP_008409338.1|1722706_1723789_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213235
NC_020990.1|WP_003950891.1|1732394_1732967_+|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	unknown	unknown	gnl|CDD|376665
NC_020990.1|WP_003950899.1|1724640_1724982_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507090.1|1711399_1712245_+|lipoprotein	unknown	unknown	gnl|CDD|225596
NC_020990.1|WP_015507091.1|1715435_1719299_+|hypothetical-protein	unknown	unknown	gnl|CDD|173412
NC_020990.1|WP_015507089.1|1710563_1711244_+|PepSY-domain-containing-protein	unknown	unknown	gnl|CDD|377032

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003950911.1|1709777_1710443_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.97186e-84
NC_020990.1|WP_003950903.1|1720622_1721642_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	2.21458e-89
NC_020990.1|WP_003950892.1|1731365_1732214_-|3-hydroxyacyl-CoA-dehydrogenase-family-protein	gnl|CDD|224170	COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism].	2.18027e-125
NC_020990.1|WP_003950906.1|1714785_1715226_+|methylmalonyl-CoA-epimerase	gnl|CDD|213772	TIGR03081, Methylmalonyl-CoA_epimerase_mitochondrial, methylmalonyl-CoA epimerase. Members of this protein family are the enzyme methylmalonyl-CoA epimerase (EC 5.1.99.1), also called methylmalonyl-CoA racemase. This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase (TIGR00642). It is known in bacteria, archaea, and as a mitochondrial protein in animals. It is closely related to lactoylglutathione lyase (TIGR00068), which is also called glyoxylase I, and is also a homodimer.	7.337e-51
NC_020990.1|WP_015507092.1|1727895_1730313_-|ATP-binding-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	4.45155e-06
NC_020990.1|WP_030306364.1|1726965_1727637_+|endonuclease-NucS	gnl|CDD|235114	PRK03298, PRK03298, endonuclease NucS.	2.9816e-177
NC_020990.1|WP_003950904.1|1719559_1720498_+|cellulose-binding-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	1.2649e-06
NC_020990.1|WP_003950893.1|1730634_1730958_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	3.80542e-20
NC_020990.1|WP_003950900.1|1723785_1724622_+|ABC-transporter-permease-subunit	gnl|CDD|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	1.91135e-05
NC_020990.1|WP_003950908.1|1712360_1713350_-|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl|CDD|224617	COG1703, ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism].	1.18363e-121
NC_020990.1|WP_008409336.1|1725240_1726275_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	8.62157e-49
NC_020990.1|WP_003950907.1|1713439_1714642_-|acetyl-CoA-C-acetyltransferase	gnl|CDD|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NC_020990.1|WP_008409338.1|1722706_1723789_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	1.17964e-91
NC_020990.1|WP_003950891.1|1732394_1732967_+|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	gnl|CDD|376665	pfam01923, Cob_adeno_trans, Cobalamin adenosyltransferase. Cobalamin adenosyltransferase This family contains the gene products of PduO and EutT which are both cobalamin adenosyltransferases. PduO is a protein with ATP:cob(I)alamin adenosyltransferase activity. The main role of this protein is the conversion of inactive cobalamins to AdoCbl for 1,2-propanediol degradation.The EutT enzyme appears to be an adenosyl transferase, converting CNB12 to AdoB12.	4.10908e-79
NC_020990.1|WP_015507090.1|1711399_1712245_+|lipoprotein	gnl|CDD|225596	COG3054, COG3054, Predicted transcriptional regulator [General function prediction only].	0.00861149
NC_020990.1|WP_015507091.1|1715435_1719299_+|hypothetical-protein	gnl|CDD|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	8.07052e-23
NC_020990.1|WP_015507089.1|1710563_1711244_+|PepSY-domain-containing-protein	gnl|CDD|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	2.23426e-07

Protein sequences

>NC_020990.1|WP_003950902.1|1721643_1722414_+|ABC-transporter-permease-subunit
MAVTQVVRSEWTKIRSVQSTVWTLGLAAVVTIGLGALISALSKSEYENLSPRDQLTFDPTFISFAGLSLGQLAMVVFGVLVVSNEYSTGMIRMSLAAVPQRGTFFFSKVAVATVLALLVSLVTTFATFFLGQALLGNLSASIGDPGVLRAVIGAALYMTLMAVFSMGVAAMLRSPMLSLGILVPFFFLVSSILGAVSATEKIGRFLPDQAGSKIMQVVAPLNDDTPYGPWGGLGIMALWVIASLAIGYALLRHRDA
>NC_020990.1|WP_003950903.1|1720622_1721642_+|ATP-binding-cassette-domain-containing-protein
MIELSGLTKRYGERVAVNNLTFTVRPGIVTGFLGPNGAGKSTTMRMILGLDRPSAGDVRIDGRHYAQLHDPLRQIGALLDAKAMHGGRTAYNHLLCLAQSNGIPASRVTEVLDTVGLTPVARKRAKGFSLGMGQRLGIAGALLGDPRILMFDEPVNGLDPEGIHWIRNLMKSLAHQGRTVFVSSHLMSEMALTAEHLVVIGQGRLMADTSMADFIRENSRSYVTMRSPERERLLDVLHAAGIAVADGPDGAVEVDGVAAPELGELAARERLVLHELSPRQASLEEAFMQLTAESVEYHAHDGDPGAVRGGPGPGGGATSGGEGQWGAGWGGPEQRRRKG
>NC_020990.1|WP_003950904.1|1719559_1720498_+|cellulose-binding-protein
MSDTSPYGFELVRRGYDRAQVDERISKLVSDRDSALTRITALEKRIEELHLETQNAQAQVADAEPSYAGLGARVEKILRLAEEEAKDLREEARRAAEQHRELAESAAQQVRNDAEAFATERKAKADDEGVRIVEKAKGEASALRAEAQKDAQSKREEADALFEETRAKAAQAAADFETNLAKRREQSERDLASRQAKAEKRLAEIEHRAEQLRLEAEKLRTDAERRARQTVETAQRQAEDIVADANAKADRIRSESERELAALTNRRDSINAQLTNVREMLATLTGAAVAAAGAPAAEDDSASRGVPAQQSR
>NC_020990.1|WP_015507091.1|1715435_1719299_+|hypothetical-protein
MRGYEGQERHRADDHLSRFEAEMDRLKTDREKAVQHAEDLGYQVEVLRAKLHEARRALATRPHSYDTADLGYQAEQMLRNAQLQADQMRSDAERELREVRAQTQRILQEHAEQQARLQAELHTEAVNRRQQLDQELAERRATVESHVNENVAWAEQLRARSESQAQRLLDESRAQAEQSLAAARAEAQRLTEEARRRLGEETENARTEAEALLRRARADAERMLNAASQQAQEATDHAEQLRTSTASEADQAHRRSAELTRAAEQRMSEADTALREATSRSEKLVAEAEATAAKRMAAAEAAGEQRTRTAREQVARLVEEATKEAEAVRAEAEELRERAVAEAEKARSEAAEKARAAAAEDSAAALAKAARTAEEVLQKASKDAEETRRSAAEEAERLRSEAEAEADRLRAEAHDLAEELKGAAKDDTKEYRAKTVELQEEARRLRGEAEQLRAEAVAEGERIRSEARREAVQQIEESATTAEELLTKAREDAAEAREAGEADGERTRAESAERAAALRKQADDALERARTEAAKLGEEAEEAAARTREEAEQAARELREETEEGVRARREEAETELVRLREEAEQRVVAAEEALTEARAEAGRLRKEAAEEAERTRTEAAERARTLSDQAVEEAEALTATAAEEAAASRAEGEAVAVRLRADAAEEAERLKAEAQEAADRLRAEAASAAERTEAEATEALERAQEEADRRRRSAEEALESARTEAGQERERAREQSEELLASARKRVEEAEAEAARLVEEADARATELVSAAEATAQQVRDSVAGLQEQAQEEIAGLRSAAEHAAERTRGEAQEEADRVRSDAHAERERASEDAARLRSEAAEELETARALAETAVSEATAESERLRADAGSYAQRLRSEASDALASAEADASKARAEARQDANRMRTEAAEQADRLVSQAATEAESLGARSAEEAERLRAEARAEAERTVTEAAEEAERLRAEAARAVAEAEERAARAREEAERVESQALAAAEELTSQARAEADRTLDEARADANKRRSEAAEQVDRLLSETAAEAEKLTTEAQQAALKATTEAESRADSMVGAARAEAERLVAEATVEGNSLVERARADADELLVGARRDATAIRERAEELRERVTAEIEELHDRARRESSEAMRNAGERCDALVKAAEEQEAKARADAKELLADASSEAGKVRIAAVRKAEGLLKEAEQKKAELVREAEQIKREAEEEAERVVAEGQRELEVLMRRRADINQEISRVQDVLEALEGFESQPAGKAAPGGSGTGVKAGASAGSSRSGGKQNDN
>NC_020990.1|WP_003950906.1|1714785_1715226_+|methylmalonyl-CoA-epimerase
MLTRIDHIGIACHDLDATVEFYRSTYGFEVFHTEVNEEQGVREAMLKINETSDGGASYLQLLEPTREDSAVGKWLAKNGEGVHHIAFGTADVDQDAADIRDKGVRVLYDEPRKGSMGSRITFLHPKDCHGVLTELVTSAPEESAEH
>NC_020990.1|WP_003950907.1|1713439_1714642_-|acetyl-CoA-C-acetyltransferase
MTGTQSTTSVIVAGARTPMGRLLGSLKSFSGADLGSFAIKAALDRAGIGGDQVQYVIMGQVLTAGAGQIPARQAAVKAGIPMNVPALTINKVCLSGLDAIALADQLIRAGEFDVVVAGGQESMTNAPHLLPKSREGYKYGAVEMLDAMAHDGLTDSFENIAMGESTEKHNTRLGIARPEQDEIAALSHQRAAAAQKNGVFEAEITPVEIPQRKGDPVLFAKDEGIRAETTAESLGKLRPAFAKDGTITAGSSSQISDGAAAVVVMSKAKAEELGLEWIAEIGAHGNVSGPDNSLQSQPSNAIAHALKKDGLAVGDLDVIEINEAFAAVAVQSMKDLGVTSEKVNVNGGAIALGHPIGMSGARLVLHLALELKRRGGGIGAAALCGGGGQGDALIVRVPKS
>NC_020990.1|WP_003950908.1|1712360_1713350_-|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MQDVPALVAQAREGRPRAVARLISLVEGASPQLRDVMAALAPLTGNAYVVGLTGSPGVGKSTTTSALVSAYRAAGKRVAVLAVDPSSPFSGGALLGDRIRMSDHASDPGVYIRSMATRGHLGGLAWAAPQAIRVLDAAGFDLVLVETVGVGQSEVEIAAQADTSVVLLAPGMGDGIQAAKAGILEIGDLYVVNKADRDGADATARELNHMLGLGEARSAGDWRPPIVKTVAAKGVGVDDLVDALEKHRGWMEERGVLAERRVARAAREVETIAVTALRSRIADLSGDARTGALAAQVVGGELSPYAAADVLLDAIAPRALGAPEESAGG
>NC_020990.1|WP_015507090.1|1711399_1712245_+|lipoprotein
MTTHRPRPASRPHRSSRALATALAAGTLLATAACSGGQEAPAARESAAAPAHHLERGPSPSPSSRLTEEGARNALITEADIEEQWQKSQAPPQSWRDSLLLGEVDAAQFVTGRSDAKECQRLVDALYDDTLLGKPSGPTALAGFEQGDSRLLYQVAGYDKKTLDASMKWLASLPETCDTFTVTGGKGGRRTVKVTETSLPDEGDARQGLKVQLKGENEGTPVTLTLDVAAVRIGTDAFTVTNGGLDGADAPTTKNAVQHGTQRLEEVQAGHTPAPTPSEIE
>NC_020990.1|WP_015507089.1|1710563_1711244_+|PepSY-domain-containing-protein
MKRNAVIAALTAVAVIGGGAAAVAVSSGDDAPATASPADRVSLVSGQESTAPADRDDDQDDDGDDQRDAKDDDRDDRDDRRDDAKDDQDDQRDDKGAAADPGNVTVAQAIAAALNHTSGTVLSADLDDDGDRRWEVEVATGGSTVHEIEVDSTTGKVVRTETDRDEDDAAAELKAVQGAKVSARDAAAAVDGAVTSVEFDDGRWEVEVGEADWTVPLDTPRASREG
>NC_020990.1|WP_003950911.1|1709777_1710443_-|response-regulator-transcription-factor
MRLLIVEDEKRLALSLAKGLTAEGYAVDVVHDGLEGLHRASESPYDLLVLDIMLPGMNGYRVCAALRAAGNDVPILMLTAKDGEYDEAEGLDTGADDYLTKPFSYVVLVARVRALLRRRAGAGASPVHTVGGLRVDTAARRVQRDGDEVALTAKEFAVLEQLVLRAGQVVSKADILEHVWDFAYDGDPNIVEVYISALRRKLGAQAIRTVRGMGYRLEAGR
>NC_020990.1|WP_008409338.1|1722706_1723789_+|ABC-transporter-ATP-binding-protein
MIEATGLTKRYGAKTAVHDLSFQVRPGTVTGFLGPNGSGKSTTMRMIVGLDEPTSGHVTIGGLPYRRVPNAPRQVGALLDAKAVHGGRSARNHLLCLAQLSGIPARRVDEVLGVVGLQDVARHRSKGFSLGMGQRLGIAAALLGDPQVLLFDEPVNGLDPEGILWVRTLMKSLAAEGRTVFVSSHLMSEMALTAEHLIVIGRGRLMADMSVREFIAANAAGFARVRVPDTEPGSREKLAAALAEEGGQVLPEPDGALRVAGLPLPRISDVAHTAGVRLWELSPHQASLEEAYMRLTQGAVDYRSTDDRRAGLHEEGAQGPEPFPVPQPGADQPGWYAPPPPRQERPAAPDLSKSDTEDPR
>NC_020990.1|WP_003950900.1|1723785_1724622_+|ABC-transporter-permease-subunit
MTTPPQQPEQPGALPGAMYTSPIPVRPTHLGHALASEWTKIRSVRSTVWTLCVFVALVVGIGLLVGWKTSGETYTDVPYTIPALFGLMLGQICLITLGVLVVTSEYGTGMIRTTFTAAPQRHRVLAAKFLVFFALAYTVSAVSITVVGLATAAINEIPSGPGENWGTSVLLGSLYVSLLGVLGLAVGSMLRHSAGAITAMLGVVLVPAIMPAFLMISPALRGIGETMLEYNAPNSLSALFGTAMYDGQAGGVPQLLALLGITLVAVAGAFALLEKRDV
>NC_020990.1|WP_003950899.1|1724640_1724982_-|hypothetical-protein
MSPRKNRSKPSRSSGRRGGGDDEPGERYGFQSAESWRGEQWSVRHISGSGPASAGKRYRCPGCDQEIPAGLPHVVAWPEHSGVDERRHWHKACWNAKDRRTTRVQRSRNAPRF
>NC_020990.1|WP_008409336.1|1725240_1726275_+|LLM-class-flavin-dependent-oxidoreductase
MHVGSFVLGGQFPGQGQGEALHRAVRSAEVAEEAGLDTVWLGEHHFVPYGTCPSAATLAALLLGRTRRVRVGTAVSVLPTTHPVALGEQAALLHLAAGGRFTLGVGRGGPWVDLEVFGAGLPAFEEGFPEALDLLLRWLREPRVGASAEGGRYAFREVAVVPSPAESLDGLPGPEVVVACTSPSSVRLAAERGLPMLLGMHTGDAEKAEMVALWRRHAREAGRDGDEIAAAAHVSAGVAQVEDGPGRATETLVKAMPGWFELGLGAHVTVDGRARAMRDPVAYTEFLCSIHPVGPPRLCADRLAATAEATGITRFALMVEGSGDLAGTEENIRRLGRDVLPLLR
>NC_020990.1|WP_003950896.1|1726369_1726762_-|hypothetical-protein
MSLDVSPALLEQAERGEVDEAAFVDCVRTSLPYAWDMISKLVAQLKVDGGEFADNQTPPPDEQARGQLLRALASDAIRGALQRHFGVRLAFQNCHRVAVFPLSSDSDERHARFTSIRGQLLNQSPELRDC
>NC_020990.1|WP_030306364.1|1726965_1727637_+|endonuclease-NucS
MPTMRLVIARCSVDYAGRLTAHLPSAPRLILVKADGSVSIHADDRAYKPLNWMSPPCTLKEGEDNVWTVVNKGGEKLVITMEEVLHDSSHELGVDPGLIKDGVEAHLQELLADRIETLGEGYTLIRREYPTAIGPVDILCRDASGATVAVEIKRRGEIDGVEQLTRYLELLNRDPHLAPVRGVFAAQEIKPQARVLATDRGIGCTVLDYNALRGIEDDKLRLF
>NC_020990.1|WP_015507092.1|1727895_1730313_-|ATP-binding-protein
MDPNHRDPHQRGDGDPHRIPGGPQPGAVERRPRPPQGPDLGQPVPPRVRTAELVAGGHLVTVNPVDGSEIEVCPPGRHPSPPVRRTPDDRAALAAAARPPAPPGVPRTHHRLLERDRERDTLVQLLARGRSVRLTGSRGSGRTVLLDAVAARCEGLAPDGVVRLDGHHRTADELLHALCAAVHLLPAHRPGPALLAELAGEIGAVVLIDDAEIGGAALDSFLAATPECAVLLACTPEVPAPGEEARVEEVVLDGIGRSGGLALLAQGAGRALSDDEVSWAGDLWFESEGLPLRFVQAGALLHQRDLLREESGSAEAPLPTVAEGAAPAALLASRLSEAARATLGFAYALGGEVPHQAHLPALVGDTHADAALTELLDCGLVTPVGNRYRLAAGVTEQLAAEGYADEGERAHTAAQHYTWWTGHPSVTPERAAAESDAVLAALTALVGGQDPARQATAVLLARTVAPVLAAGLAWGAWERVLRSGQEAARLSGEVAEEAYFHHELGILALCQDRLDRARAELEAAVALRGALADKRGTVAGRRALALVADRAGETVPVTRAVLPTDGPPVPPRRDGLGTPPTGFPRTTPAAGVTRVQPAASATGATVVGGPAATAAKDGRPGRAAVTGARRNLVAAGAGALLVAVLGTVVTLGAINGDDEEPASVDRVTTEQTTPEDEGDEGTEAERPADSAEPSTDPGEDGVTGTPDDPTPGDSGSPSESESDEPSSSPTDRPTTSPSDRPTTKPPTTPPTSSKPPTTPPPSSPDPEPSDTTPPTEDPDPEDPEPGTDNSASGPAPEPSTSQTLS
>NC_020990.1|WP_003950893.1|1730634_1730958_-|STAS-domain-containing-protein
MYIRGDHAELVVGGRLDVRSAADARTVLHSAVDDGAGDLVLDLAALDSWDATGLGVIMGAHRRAGRCGRRLVLRSVPPQMQRLLVATRLHRILAIEGGIGLDSLPRA
>NC_020990.1|WP_003950892.1|1731365_1732214_-|3-hydroxyacyl-CoA-dehydrogenase-family-protein
MARKLAVIGAGLMGSGIAQVSAQAGWDVVLRDVTDAALTRGTDGIKSSFDRFVAKGKLSAEDAGAALGRITTTTDLEGAADADIVVEAVFEQLDVKHEIFRTLDKLVREDTVLASNTSAIPITKIAAVTERPERVVGAHFFSPVPMMQLCELVRGYKTSDETLARTREFAESTGKTCIVVNRDVAGFVTTRLISALVVEAAKLYESGVATAEDIDLACKLGFGHAMGPLTTADLTGVDILLHATQNIYTESQDEKFAPPELMRRMVDAGDLGRKSGEGFYSY
>NC_020990.1|WP_003950891.1|1732394_1732967_+|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase
MVNLTRIYTRTGDKGTTALGDMSRTAKTDPRIAAYADANEANAAIGTALALGDLPEDIAKVLLRVQNDLFDVGADLSTPVVENPEYPPLRVEQSYIDKLEADCDTYLEQVEKLRSFILPGGTPGAALLHQACTVVRRAERSTWAAAEVFGDTMNPLAATYLNRLSDLLFILARVANKEVGDVLWVPGGER

Crispr_ID: NC_020990_6

• CRISPR_ID: NC_020990_6
• CRISPR_location: 1858904-1858995
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_6

Consensus_repeat	Method
GGCCTCAAACGCCGGCCGGGCTGG	CRISPRCasFinder

spacers of NC_020990_6

>6.1|1858928|44|NC_020990|CRISPRCasFinder
GTGATGATGCTTGCTGTCCGGCTTCACCGCGCCGGTCCACGATC

CRISPR arrays and Neighbor proteins around NC_020990_6

CRISPR arrays

The CRISPR arrays of NC_020990_6

>merge|NC_020990|6|1858904-1858995|CRISPRCasFinder
GGCCTCAAACGCCGGCCGGGCTGGGTGATGATGCTTGCTGTCCGGCTTCACCGCGCCGGTCCACGATCGGCCTCAAGCGCCGGCCGGGCTGG

>NC_020990|6|6|1858904-1858995|CRISPRCasFinder
GGCCTCAAACGCCGGCCGGGCTGG	GTGATGATGCTTGCTGTCCGGCTTCACCGCGCCGGTCCACGATC
GGCCTCAAGCGCCGGCCGGGCTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003950781.1|1853524_1853938_+|hypothetical-protein	unknown	unknown	gnl|CDD|235217
NC_020990.1|WP_008415733.1|1857332_1858799_-|PAS-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl|CDD|378836
NC_020990.1|WP_003950764.1|1872737_1873790_+|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl|CDD|153108
NC_020990.1|WP_086014580.1|1866053_1866758_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NC_020990.1|WP_003950773.1|1860890_1862384_-|glycoside-hydrolase-family-3-protein	unknown	unknown	gnl|CDD|224389
NC_020990.1|WP_015507120.1|1867258_1869493_+|carbon-starvation-protein-A	unknown	unknown	gnl|CDD|184976
NC_020990.1|WP_003950765.1|1870362_1872738_+|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl|CDD|274170
NC_020990.1|WP_003950767.1|1869489_1869732_+|YbdD/YjiX-family-protein	unknown	unknown	gnl|CDD|377308
NC_020990.1|WP_003950782.1|1853045_1853306_+|UBP-type-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|366940
NC_020990.1|WP_015507116.1|1850381_1851362_+|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|225313
NC_020990.1|WP_003950771.1|1863285_1864293_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_020990.1|WP_003950774.1|1859961_1860744_+|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl|CDD|179028
NC_020990.1|WP_003950772.1|1862389_1863289_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_020990.1|WP_003950783.1|1851371_1852967_-|Na+/H+-antiporter	unknown	unknown	gnl|CDD|223104
NC_020990.1|WP_003950770.1|1864384_1865683_-|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270450
NC_020990.1|WP_003950785.1|1849756_1850350_+|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NC_020990.1|WP_003950777.1|1856854_1857112_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NC_020990.1|WP_008415737.1|1854168_1855032_+|RNA-polymerase-sigma-factor-SigF	unknown	unknown	gnl|CDD|274373
NC_020990.1|WP_003950779.1|1855567_1856536_+|diacylglycerol-kinase	unknown	unknown	gnl|CDD|224513
NC_020990.1|WP_015507118.1|1855041_1855467_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003950781.1|1853524_1853938_+|hypothetical-protein	gnl|CDD|235217	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional.	7.74906e-18
NC_020990.1|WP_008415733.1|1857332_1858799_-|PAS-domain-containing-sensor-histidine-kinase	gnl|CDD|378836	pfam12282, H_kinase_N, Signal transduction histidine kinase. This domain is found in bacteria. This domain is about 150 amino acids in length. This domain is found associated with pfam07568, pfam08448, pfam02518. This domain has a single completely conserved residue P that may be functionally important. This family is mostly annotated as a histidine kinase involved in signal transduction but there is little published evidence to support this.	6.35995e-63
NC_020990.1|WP_003950764.1|1872737_1873790_+|ribonucleotide-diphosphate-reductase-subunit-beta	gnl|CDD|153108	cd01049, RNRR2, Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain. Ribonucleotide Reductase, R2/beta subunit (RNRR2) is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The RNR protein catalyzes the conversion of ribonucleotides to deoxyribonucleotides and is found in all eukaryotes, many prokaryotes, several viruses, and few archaea. The catalytically active form of RNR is a proposed alpha2-beta2 tetramer. The homodimeric alpha subunit (R1) contains the active site and redox active cysteines as well as the allosteric binding sites. The beta subunit (R2) contains a diiron cluster that, in its reduced state, reacts with dioxygen to form a stable tyrosyl radical and a diiron(III) cluster. This essential tyrosyl radical is proposed to generate a thiyl radical, located on a cysteine residue in the R1 active site that initiates ribonucleotide reduction. The beta subunit is composed of 10-13 helices, the 8 longest helices form an alpha-helical bundle; some have 2 addition beta strands. Yeast is unique in that it assembles both homodimers and heterodimers of RNRR2. The yeast heterodimer, Y2Y4, contains R2 (Y2) and a R2 homolog (Y4) that lacks the diiron center and is proposed to only assist in cofactor assembly, and perhaps stabilize R1 (Y1) in its active conformation.	1.34201e-108
NC_020990.1|WP_086014580.1|1866053_1866758_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.50583e-73
NC_020990.1|WP_003950773.1|1860890_1862384_-|glycoside-hydrolase-family-3-protein	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	2.29796e-74
NC_020990.1|WP_015507120.1|1867258_1869493_+|carbon-starvation-protein-A	gnl|CDD|184976	PRK15015, PRK15015, carbon starvation protein CstA.	0
NC_020990.1|WP_003950765.1|1870362_1872738_+|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl|CDD|274170	TIGR02506, Ribonucleoside-diphosphate_reductase_large_subunit, ribonucleoside-diphosphate reductase, alpha subunit. This model represents the alpha (large) chain of the class I ribonucleotide reductase (RNR). RNR's are responsible for the conversion of the ribose sugar of RNA into the deoxyribose sugar of DNA. This is the rate-limiting step of DNA biosynthesis. Class I RNR's generate the required radical (on tyrosine) via a "non-heme" iron cofactor which resides in the beta (small) subunit. The alpha subunit contains the catalytic and allosteric regulatory sites. The mechanism of this enzyme requires molecular oxygen. E. Coli contains two versions of this enzyme which are regulated independently (NrdAB and NrdEF, where NrdA and NrdE are the large chains). Most organisms contain only one, but the application of the gene symbols NrdA and NrdE are somewhat arbitrary. This model identifies RNR's in diverse clades of bacteria, eukaryotes as well as numerous DNA viruses and phage. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0
NC_020990.1|WP_003950767.1|1869489_1869732_+|YbdD/YjiX-family-protein	gnl|CDD|377308	pfam04328, Sel_put, Selenoprotein, putative. This entry includes a group of putative selenoproteins from Proteobacteria, Actinobacteria and Firmicutes. The invariant cysteine at the C-terminus is encoded by a TGA Sec codon in some Epsilonproteobacteria, suggesting a redox activity for the protein.	4.50459e-19
NC_020990.1|WP_003950782.1|1853045_1853306_+|UBP-type-zinc-finger-domain-containing-protein	gnl|CDD|366940	pfam02148, zf-UBP, Zn-finger in ubiquitin-hydrolases and other protein.	6.31137e-07
NC_020990.1|WP_015507116.1|1850381_1851362_+|pyridoxal-phosphate-dependent-enzyme	gnl|CDD|225313	COG2515, Acd, 1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism].	4.75748e-42
NC_020990.1|WP_003950771.1|1863285_1864293_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.24187e-60
NC_020990.1|WP_003950774.1|1859961_1860744_+|glucosamine-6-phosphate-deaminase	gnl|CDD|179028	PRK00443, nagB, glucosamine-6-phosphate deaminase; Provisional.	1.24907e-131
NC_020990.1|WP_003950772.1|1862389_1863289_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.25204e-83
NC_020990.1|WP_003950783.1|1851371_1852967_-|Na+/H+-antiporter	gnl|CDD|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	8.95006e-77
NC_020990.1|WP_003950770.1|1864384_1865683_-|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.42611e-116
NC_020990.1|WP_003950785.1|1849756_1850350_+|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	5.27237e-21
NC_020990.1|WP_003950777.1|1856854_1857112_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.80007e-28
NC_020990.1|WP_008415737.1|1854168_1855032_+|RNA-polymerase-sigma-factor-SigF	gnl|CDD|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	4.95692e-127
NC_020990.1|WP_003950779.1|1855567_1856536_+|diacylglycerol-kinase	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	3.41952e-42

Protein sequences

>NC_020990.1|WP_008415733.1|1857332_1858799_-|PAS-domain-containing-sensor-histidine-kinase
MNELVRQHTALGDTDLEWLHLLVSEWQLLSDLSFADLILWVPTRDGTRYVSVAQMRPNTGPTSYQNDMVGHLVPRGRRPMLDLALDEGRIVREGDPEWREEVPVRVESIPVCREGRILGVIARNTNLLTVRTPSRLELTYLQSASDLAQMIAAGSFPFADQQGDTDVSPRAGDGLIRLDADGIVQYASPNALSAYHRLGLAADLVGHHLGQTTTELAPARGAVDEAMVKLASGWAPREAEVEGSDGVIQLRAIPLRPKGTHIGSLVLLRDVTELRRRERELMTKDATIREIHHRVKNNLQTVAALLRLQARRIDSERGREALVEAVRRVGSIAIVHETLSQNLDERVEFDEIADRVLAMVAEISPGRVEGRRSGRFGILDAEVATPLSMVLTEVLQNALEHGFRPGDTGEVEVSAVRGGTRKDARLLITVQDNGVGLPEGFDAHTAGNLGLQIVRTLVEGELGGTFDMNSAPEGGTRVLLDIPVRGDL
>NC_020990.1|WP_003950777.1|1856854_1857112_+|WhiB-family-transcriptional-regulator
MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVAEQCLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARNASA
>NC_020990.1|WP_003950779.1|1855567_1856536_+|diacylglycerol-kinase
MRALLVVNPAATTTSARTRDVLIHALASEVKLEAVTTEYRGHARDIGRLAAASSDVDMVVALGGDGTVNEVVNGLLHDGPDPDRLPGLAVVPGGSTNVFARALGLPNDPVEATGALLDALRTGSQRTVSLGLASGTPGSEDEAVPGRWFTFTAGLGFDAGVIGRVEQHRERGRRSTHPLYVRQVLRQFVGEPHRRHGLITLEQPGQEPVDDLVLSVVCNTAPWTYLGNRPIYASPRASFDTGLDIFGLSRLSTMAVARYGTQLLASSPERGPRGRHALSRHDLTEFTLHSKAPLPFQMDGDHLGLRTSVTFAGVRRALRVIV
>NC_020990.1|WP_015507118.1|1855041_1855467_-|hypothetical-protein
MSTEQTPTDPGPRPTRLTVVAALAAVEGLALVVVGLVLAVRALLGDGELRSALTGGLTLVALGVIPLAAARGLLARRSWSRGPAIITQILALPVAWQFLQADSVLIPGGVVLAVVAISALVMLVNPATTIDLGIRPPGAER
>NC_020990.1|WP_008415737.1|1854168_1855032_+|RNA-polymerase-sigma-factor-SigF
MTEDKHQDEKPGGQDEQPEHQKDQAPPAGAPVDRPDPHDRSGARALFIELRTLPAGGPEYAELRNRLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLSLTSATAELSQRHGRSPTVHELAEKLGISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLGSEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTLAQLREKLLVEE
>NC_020990.1|WP_003950781.1|1853524_1853938_+|hypothetical-protein
MSPIAGEPGTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDEIEDLRIAVDEACAILLQQAVPGSVLGCVFRLIDDSLEVTVSAPTTDGKAPERDTFAWTVLSALAGKVDSSVAEDNTVSISLHKQRGAGPGPA
>NC_020990.1|WP_003950782.1|1853045_1853306_+|UBP-type-zinc-finger-domain-containing-protein
MNKCTHVTELPHPEPAPSADTCLECLEVGSNPVQLRKCLYCGHVACCDSSPCRHATAHFRESGHPVMRSAEPGESWRWCYADGSIV
>NC_020990.1|WP_003950783.1|1851371_1852967_-|Na+/H+-antiporter
MDVLPLLLLVAGSTSVAGAARRTAVPAPLILVTAGLLVSYIPGVPAYTLDPEIVLPLVLPPLLHTAAMDSSYLDLRAQLRSVALLSVGYTLFATLVVGWAVHLIVPDLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLVNDATAITAYRVAVAAAIGESAGLLHAGTEFLVASLGGVAVGLVLMVPLHWLRTHLREPLLKNTLSLLIPFAAYALAEYAGASGVLAVVVVALYLGHHSWQVDFATRLQEDAVWKMVAFVLESAVFALIGLQLPLVVGGLGDYHVGEVLWYALAVFLVVVATRFVWTYPAVFLPRLVSRRIRAREPDPTWKGPFVVAWAGMRGVVSLAIAFSIPHAVHEGGPFPYRNLILFLTFTTVIGTLVVQGLTLPALIRLLRLPGRDVRAETLLEAQAQNAASEAAERRLDALLDDPRNALPQPLADRLRSVLERRRNAVWERLGTVNPQTGESVDDTYRRLARSMIASEREVFVALRDRRHIDDEMLRDLLRRLDLEEAAAYREEG
>NC_020990.1|WP_015507116.1|1850381_1851362_+|pyridoxal-phosphate-dependent-enzyme
MSAHPDPVPPVPEPSVPRARDGRAHREPVRPLLPSPVQELREPAFERYGVRLLLKRDDLIHPDIPGNKWRKLAPVLREADGRTVVTFGGAWSNHLRATAAAGRLLGFPTVGVVRGEELAGRPLNPSLARCRADGMRLAFVSRSRYRLRGDAAVRDALVAEAAGPGRPVRVVPEGGSDAAAVRACAVLGEELAVLRESVPAVAVACGTGGTLAGLAAGLAPEQEAVGVAVLKGGFLGAGVAAHQRAAFGGERGRWTVEDGFHHGGYARTTPELEEFATAFEQRHGLGVERVYVAKLLHGLAALAADGRFRRGTALAAVVTGRPFPEA
>NC_020990.1|WP_003950785.1|1849756_1850350_+|N-acetylmuramoyl-L-alanine-amidase
MAPPMSADRFLKALKDEGVTVVEVGSWRSHNRNSKGAWGPVNGVMIHHTVTSGSARTVDICRNGYSGLPGPLCHGVITKDGRVHLVGYGRANHAGLGDDNVLAAVIAERASYPPVNEANTDGNARFYGFECENLGDGKDPWTSAQLDAIERVSAAICRVHGWNQQSVIGHLEWQPGKIDPRGFTMKSMRERIKGRLK
>NC_020990.1|WP_003950774.1|1859961_1860744_+|glucosamine-6-phosphate-deaminase
MEVVIVPDARTGGELIADAIAALLRRKPDALLGVATGSTPLPVYQALAAKVADGAVDASRARICQLDEYVGLPPGHPESYRSVVLREVVEPLGLPASSFMGPDGSAEDVQAACEAYDAALGVAGGVDLQLLGIGTDGHIGFNEPCSSLASRTRIKTLTEQTRRDNARFFDSLDEVPHHVITQGIGTILDARHLVLLATGEGKAQAVADTVEGPVASVVPASALQLHPHATVVVDEAAASKLRLAPYFRDTYAAKPKWQGL
>NC_020990.1|WP_003950773.1|1860890_1862384_-|glycoside-hydrolase-family-3-protein
MTAQPTTVSGDQLTRDALAVLQPGFTGTEAPEWLLRQIRDGLTSVGLFGRNITSPGQLSALTAQLRAEREDILVAIDEEGGDVTRLEVVDGSSVPGNHALGAVDDPELTRAVAHELARRLADCGVHLNWAPSADVNSDPDNPVIGVRSFGSDPDLVARHTAAYVEGMQSAGVAACTKHFPGHGDTAVDSHHALPTIGVGADVLAARDLTPFRAAIAAGSKAVMSAHILVPALDPDQPATLSRRILTGLLREELGYEGLIVTDGMEMQAISATYGIERGSVLAIAAGADAICVGGGLADEQTVIKLRDTLVAAVRSGELAEERLADAAARVRALAAWTTATPRATGERTPDIGLVAARRALEITRTEEHRALTGTPHVVSFAPVANIAVGDETPWGVAAELAARLPGTTSASYTEQDGAELAARVLAEAGERRLVAVVRDEHRHPWMARALDGLLAARPDTVVVEMGIPQSAPRGSLHVATHGASRVCGQAAAEAVTT
>NC_020990.1|WP_003950772.1|1862389_1863289_-|carbohydrate-ABC-transporter-permease
MSTATQTPRTGTPAAEAPEPQVIRPDRKRTRLGYNIIALVTAAVMAFPVYWLIVSALRPNHEIRSYDQTLWPSSITFDNFARAVKQDNFVTAIQSSLIVSITAVVGGMIIATLAALAIGRFRFFGRRALLMVLILVQMLPPTAMLIPIYAQLNAMGGLDEYWGLIVVYLVSTLPFAVVMIRGFVVNIPVELEESAMVDGCTRMGAFRRVIFPLLAPGLAAASIFALVNAWNEYLFAYILINDNSKYTLNVWLMTFTTERGTDYGALMAASTMIALPVVIFFMIIQSKMAAGLTSGAVKG
>NC_020990.1|WP_003950771.1|1863285_1864293_-|sugar-ABC-transporter-permease
MTAAETQAADPPAAIPSAPLDKGTPPPAGTPSNSGPPRRKKGALLPYLLILPAIIAVAAVYAFPLVKSVIMSFQDMGRRELWSGNTPPWVGFDQYTAILADSEFWYVVGRTVLFMAVCVTLTMAIGLLLALLMMRLTTWVRIVLTVALIAAWSMPLMVAASIFRWLSDSDYGLINTLIAKVAGEDFLGHNWFLNPWQGFGIITALVVWGAIPFVVVTLYAALTQVPKELEEAAALDGASATGIFRFVTWPVIKPVFVMVTTLSVIWDFNVFGQIWLLRGNKPEPEYETLGLYSFSKAFSSTSFSQGTAIALITVVLLSGVAVYYLRQLMKTGEVE
>NC_020990.1|WP_003950770.1|1864384_1865683_-|sugar-ABC-transporter-substrate-binding-protein
MKRKLIAAIGVAGMMAGLAACGDSETASNAKPEDRKENLTVWLMVDAQSTWPELVKDVNAQFKKKYPNVKVNVQYQGWADKAKKLDTALGGDKFPDVVELGNTETMQYILNGALAEIDPKKYENSDTWIQGLTDTCTFEGKQYCVPYYAGARVAVYNQEMLKKATGSDALPETEDAFLKAMDKVSKEYGEKDKRYSSLYLPGRYWYAAMSYVAAYGGQIAEYDEGSKEWKGTLSSPESQKGIQHFVDLVKKYNKADLTKDEQDHANVMANEKAGVIYGNGWEAGSVVDGKNNGNAKLEGKIATAGMPGPEGKALPSFIGGSDLGIVEKSKAKDLAEEWVSLFTNEKSMEVLASKNILPNNTKQLEPLKEKPETAAVANAVPDAWFTPIAPGWTSIEKEEVLKNMLLQIIKGDSVEKAAKAADAKIDELINKG
>NC_020990.1|WP_086014580.1|1866053_1866758_+|GntR-family-transcriptional-regulator
MPKYYRLKRHLLDMTRTLPPGTSVPPERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRAQGLEPTSQLLEVGYITADDSLASLLDITAGGRVLRIERLRLASGEPMAIETTHLSAKRFPALRRSLVKYTSLYTALYEVYGVRPAEAEETIETSLATPREAALLATDVGLPMLMLSRHSRDESGAPVEWVRSVYRGDRYKFLARLKRPVE
>NC_020990.1|WP_015507120.1|1867258_1869493_+|carbon-starvation-protein-A
MAEPAPPASGNRKLSAKSIAVWSLVAVVGAIAWSVLALSRGEEISAIWMLAAALGSYAIAYRFYSRFIANKVLKVDKNRATPAERLDNGVDFQPTDRRVLFGHHFAAIAGAGPLVGPILAAQMGYLPGTIWIVAGVIFAGAVQDMVTLFFSTRRNGRSLGQMARDEIGPVGGVAALIAVFMIMIILLAVLALVIVNALAGSPWGVFSIGMTIPIALFMGVYLRTLRPGKVTEVSVLGVALLLLAIVGGGWVAESSMADFFTLEPGTLVIWMVVYGFFASVLPVWMLLAPRDYLSTFMKVGTIVLMAVCVIIAMPTLKMDGVTSFATSGAGPVFSGSLFPFVFITIACGALSGFHSLVSSGTTPKMVQKETQIRMIGYGAMLTESFVAIMAMIAACIIDPGLYFAINSPAGVLGDTVQSASEAVANLGFTISPDQLAQAAKDVEEASLLSRTGGAPTFALGMAEIFAAALGGAGMKAFWYHFAIMFEALFILTTVDAGTRVGRFMLQDTLGNVWKPMRRVSWWPGVWLTSAVVVGCWGYFLWVGVHDPLGGINQLFPLFGIANQLLAAVALAVCTTLLIKSGRLKWAWVTGIPLAWDVAVTLTASWQKVFSDNPAIGFFAQRAKYQDGIDAGEVLAPAKSMSDMHTVVTNSTVDGVLSIVFAVLIIIVLVDAGRVSYNAIRKPESVKLAEAPFEQSKIVAPAGMFATSEEKAELALVGAGAPASASAGDGDGDGDAPAKQGGGQA
>NC_020990.1|WP_003950767.1|1869489_1869732_+|YbdD/YjiX-family-protein
MSGEAAHHPGRLGVLAHRVRAGVRWIGWYVREVSGETAYEKYAAHVRRHDPDAEVMTRRQFERSRMDAREADPRDGFRCC
>NC_020990.1|WP_003950765.1|1870362_1872738_+|ribonucleoside-diphosphate-reductase-subunit-alpha
MTIAPADPSTADVRAEEIQGPGGALLRTLTDLTADLPDTDPGRVAAAALRGRNAASDEAELRSLATEAAAGLISEDPAYSRLAARLLTRTIAEEAAGQGVTTFTESVATGHREGLIADRTAAFVTAHAERLDALVDPAADDRFGYFGLRTVHSRYLLRHPHTRQVIETPQHFMLRVACGLAEDDSARALDEVASLYRLMSALSYLPSSPTLFNSGTRHPQMSSCYLLDSPKDELESIYDRYHQVARLSKHAGGIGLAYSRIRARGSLIRGTNGHSNGIVPFLNTLDASVAAVNQGGRRKGAAAVYLETWHADVEEFLELRDNTGEEARRTHNLNLAHWIPDEFMRRVDADADWSLFSPSDVPELTDLWGDAFDAAYRAAEARGLARRTIPARELYGRMMRTLAQTGNGWMTFKDASNRTANQTALPGHTVHSSNLCTEILEVTDDGETAVCNLGSVNLGAFVDGGAIDWERLDEAVRTAVVFLDRVVDINFYPTEQAERSNSRWRPVGLGAMGLQDVFFQLRLPFDSPEAQRLSTRIAERIMLTAYETSCDLAEKNGPLPNWDRTRTAQGVLHPDHYDTDLAWPERWEALRARVAESGMRNALLLAIAPTATIASIAGVYECIEPQVSNLFKRETLSGEFLQVNSYLVEDLKRLGVWDARTREALREASGSVQGFAWIPEELRALYRTAWELPQRGLIDMAAARTPFLDQSQSLNLFMETPTIGKLSSMYAYAWKKGLKTTYYLRSRPATRIARAAGGSAPATATVPAQAAPDAEAIACSLENPESCEACQ
>NC_020990.1|WP_003950764.1|1872737_1873790_+|ribonucleotide-diphosphate-reductase-subunit-beta
MTTPDTTPAANAHTVGAAKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLHSDVADLAKLSPGEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEEAVHVQFYLTLLDTYLPDPADRADAFAAVENIPSIREKAEFCFRWMDSVDKLDQLESQADRRKFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFDVVDTVRKEEPELFDDKLQEQVVAMLKEAVEAELQFARDLCGDGLPGMNTESMREYLECVADQRLTRLGFAPVYGSQNPFSFMELQGVQELTNFFERRVSAYQVAVEGTVSFDDDF

Crispr_ID: NC_020990_7

• CRISPR_ID: NC_020990_7
• CRISPR_location: 2099060-2099211
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_020990_7

Consensus_repeat	Method
GACGGCCTCAAACGCCGGCCGGGCTGAG	PILER-CR

spacers of NC_020990_7

>7.1|2099089|36|NC_020990|PILER-CR
CTGGGCTCCGGGTCCGGCTCCGGGGTGCCGGTCACT
>7.2|2099154|35|NC_020990|PILER-CR
GGTGGCTGAGGTCCGGATCGCCGCCACCCGTCCAA

CRISPR arrays and Neighbor proteins around NC_020990_7

CRISPR arrays

The CRISPR arrays of NC_020990_7

>merge|NC_020990|7|2099060-2099211|PILER-CR
GCCTCAAGCGCCGGCCGGGCTGTCCTGGGCTCCGGGTCCGGCTCCGGGGTGCCGGTCACTGACTGGCCTCAAACGCCGGCCGGGCTGAGGGTGGCTGAGGTCCGGATCGCCGCCACCCGTCCAAGACGGCCTCAAACGCCGGCCGGGCTGAG

>NC_020990|7|2|2099060-2099211|PILER-CR
GCCTCAAGCGCCGGCCGGGCTGTCCTGGG	CTCCGGGTCCGGCTCCGGGGTGCCGGTCACTGACTG
GCCTCAAACGCCGGCCGGGCTGAGGGTGG	CTGAGGTCCGGATCGCCGCCACCCGTCCAAGACGG
CCTCAAACGCCGGCCGGGCTGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003950578.1|2091075_2091897_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|226953
NC_020990.1|WP_003950570.1|2099400_2099784_-|hypothetical-protein	unknown	unknown	gnl|CDD|227406
NC_020990.1|WP_003950567.1|2101152_2102439_+|PTS-transporter-subunit-EIIC	unknown	unknown	gnl|CDD|273923
NC_020990.1|WP_003950565.1|2103041_2103791_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293802
NC_020990.1|WP_003950560.1|2106232_2107678_-|amino-acid-permease	unknown	unknown	gnl|CDD|224038
NC_020990.1|WP_003950564.1|2104071_2105022_-|cysteine-synthase	unknown	unknown	gnl|CDD|273463
NC_020990.1|WP_015507166.1|2092119_2094450_+|penicillin-binding-protein	unknown	unknown	gnl|CDD|223815
NC_020990.1|WP_023417316.1|2094997_2095300_-|co-chaperone-GroES	unknown	unknown	gnl|CDD|197951
NC_020990.1|WP_003950572.1|2096557_2098057_+|glycine-betaine/L-proline-transporter-ProP	unknown	unknown	gnl|CDD|340924
NC_020990.1|WP_008405025.1|2089158_2090169_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213234
NC_020990.1|WP_003950568.1|2100752_2100986_-|PTS-transporter-subunit-EIIB	unknown	unknown	gnl|CDD|238130
NC_020990.1|WP_003950573.1|2095917_2096385_+|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl|CDD|224146
NC_020990.1|WP_003950566.1|2102444_2102828_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950569.1|2099916_2100642_-|ribonuclease-PH	unknown	unknown	gnl|CDD|178914
NC_020990.1|WP_010642676.1|2095416_2095770_-|DUF3618-domain-containing-protein	unknown	unknown	gnl|CDD|378834
NC_020990.1|WP_003950561.1|2105697_2106132_-|M67-family-metallopeptidase	unknown	unknown	gnl|CDD|163701
NC_020990.1|WP_003950576.1|2094520_2094841_-|quaternary-ammonium-compound-efflux-SMR-transporter-SugE	unknown	unknown	gnl|CDD|171110
NC_020990.1|WP_037629993.1|2098426_2099029_-|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	unknown	unknown	gnl|CDD|234648
NC_020990.1|WP_003950579.1|2090213_2091083_-|transporter	unknown	unknown	gnl|CDD|253605
NC_020990.1|WP_003950563.1|2105021_2105306_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340594

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003950578.1|2091075_2091897_-|ABC-transporter-permease	gnl|CDD|226953	COG4587, COG4587, ABC-type uncharacterized transport system, permease component [General function prediction only].	5.18996e-29
NC_020990.1|WP_003950570.1|2099400_2099784_-|hypothetical-protein	gnl|CDD|227406	COG5074, COG5074, t-SNARE complex subunit, syntaxin [Intracellular trafficking and secretion].	0.000981656
NC_020990.1|WP_003950567.1|2101152_2102439_+|PTS-transporter-subunit-EIIC	gnl|CDD|273923	TIGR02002, PTS_system_glucose-specific_IIABC_component, PTS system, glucose-specific IIBC component. This model represents the combined B and C domains of the PTS transport system enzyme II specific for glucose transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, glucose-specific IIABC component" while the B. subtilus enzyme also contains an enzyme III domain which appears to act independently of the enzyme II domains. This family is most closely related to the N-acetylglucosamine-specific PTS enzymes (TIGR01998). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	5.48638e-135
NC_020990.1|WP_003950565.1|2103041_2103791_-|MBL-fold-metallo-hydrolase	gnl|CDD|293802	cd07716, RNaseZ_short-form-like_MBL-fold, uncharacterized bacterial subgroup of Ribonuclease Z, short form; MBL-fold metallo-hydrolase domain. The tRNA maturase RNase Z (also known as tRNase Z or 3' tRNase) catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Two forms of RNase Z exist in eukaryotes, one long (ELAC2) and one short form (ELAC1), the former may have resulted from a duplication of the shorter enzyme. Only the short form exists in bacteria. Members of this bacterial subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	4.14449e-84
NC_020990.1|WP_003950560.1|2106232_2107678_-|amino-acid-permease	gnl|CDD|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NC_020990.1|WP_003950564.1|2104071_2105022_-|cysteine-synthase	gnl|CDD|273463	TIGR01136, Cysteine_synthase, cysteine synthase. This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family].	5.57894e-139
NC_020990.1|WP_015507166.1|2092119_2094450_+|penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	3.49047e-139
NC_020990.1|WP_023417316.1|2094997_2095300_-|co-chaperone-GroES	gnl|CDD|197951	smart00883, Cpn10, Chaperonin 10 Kd subunit. The chaperonins are 'helper' molecules required for correct folding and subsequent assembly of some proteins. These are required for normal cell growth, and are stress-induced, acting to stabilise or protect disassembled polypeptides under heat-shock conditions. Type I chaperonins present in eubacteria, mitochondria and chloroplasts require the concerted action of 2 proteins, chaperonin 60 (cpn60) and chaperonin 10 (cpn10). The 10 kDa chaperonin (cpn10 - or groES in bacteria) exists as a ring-shaped oligomer of between six to eight identical subunits, while the 60 kDa chaperonin (cpn60 - or groEL in bacteria) forms a structure comprising 2 stacked rings, each ring containing 7 identical subunits. These ring structures assemble by self-stimulation in the presence of Mg2+-ATP. The central cavity of the cylindrical cpn60 tetradecamer provides as isolated environment for protein folding whilst cpn-10 binds to cpn-60 and synchronizes the release of the folded protein in an Mg2+-ATP dependent manner. The binding of cpn10 to cpn60 inhibits the weak ATPase activity of cpn60.	8.91339e-24
NC_020990.1|WP_003950572.1|2096557_2098057_+|glycine-betaine/L-proline-transporter-ProP	gnl|CDD|340924	cd17366, MFS_ProP, Proline/betaine transporter of the Major Facilitator Superfamily of transporters. This subfamily is composed of Escherichia coli proline/betaine transporter, also called proline porter II (PPII), and similar proteins. ProP is a proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response. The ProP subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0
NC_020990.1|WP_008405025.1|2089158_2090169_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213234	cd03267, ABC_NatA_like, ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA. NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.	9.52017e-125
NC_020990.1|WP_003950568.1|2100752_2100986_-|PTS-transporter-subunit-EIIB	gnl|CDD|238130	cd00212, PTS_IIB_glc, PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	1.66536e-24
NC_020990.1|WP_003950573.1|2095917_2096385_+|thioredoxin-dependent-thiol-peroxidase	gnl|CDD|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	2.2015e-66
NC_020990.1|WP_003950569.1|2099916_2100642_-|ribonuclease-PH	gnl|CDD|178914	PRK00173, rph, ribonuclease PH; Reviewed.	2.01732e-169
NC_020990.1|WP_010642676.1|2095416_2095770_-|DUF3618-domain-containing-protein	gnl|CDD|378834	pfam12277, DUF3618, Protein of unknown function (DUF3618). This domain family is found in bacteria, and is approximately 50 amino acids in length.	9.91538e-11
NC_020990.1|WP_003950561.1|2105697_2106132_-|M67-family-metallopeptidase	gnl|CDD|163701	cd08070, MPN_like, Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding). This family contains archaeal and bacterial MPN (also known as Mov34, PAD-1, JAMM, JAB, MPN+)-like domains. These domains contain the signature JAB1/MPN/Mov34 metalloenzyme (JAMM) motif, EXnHS/THX7SXXD, which is involved in zinc ion coordination and provides the active site for isopeptidase activity for the release of ubiquitin from ubiquitinated proteins (thus having deubiquitinating (DUB) activity) that are tagged for degradation. The JAMM proteins likely hydrolyze ubiquitin conjugates in a manner similar to thermolysin, in which the zinc-polarized aqua ligand serves as the nucleophile, compared with the classical DUBs that do so with a cysteine residue in the active site.	1.90861e-37
NC_020990.1|WP_003950576.1|2094520_2094841_-|quaternary-ammonium-compound-efflux-SMR-transporter-SugE	gnl|CDD|171110	PRK11431, PRK11431, quaternary ammonium compound efflux SMR transporter SugE.	1.18024e-29
NC_020990.1|WP_037629993.1|2098426_2099029_-|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	gnl|CDD|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	2.66722e-102
NC_020990.1|WP_003950579.1|2090213_2091083_-|transporter	gnl|CDD|253605	pfam06182, ABC2_membrane_6, ABC-2 family transporter protein. This family acts as the transmembrane domain (TMD) of ABC transporters. The family includes proteins responsible for the transport of herbicides.	2.39766e-59
NC_020990.1|WP_003950563.1|2105021_2105306_-|MoaD/ThiS-family-protein	gnl|CDD|340594	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins. CysO, also termed 9.5 kDa culture filtrate antigen cfp10A, together with CysM (Cysteine synthase M), forms a protein complex CysM-CysO that represents a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. The replacement of the acetyl group of O-acetylserine by CysO thiocarboxylate to generate a protein-bound cysteine is catalyzed by CysM in a pyridoxal 5?-phosphate (PLP)-dependent manner. The family also includes QbsE that functions as the sulfide donor for the biosynthesis of thioquinolobactin in Pseudomonas fluorescens. A JAMM motif protein QbsD catalyzes removal of the carboxy-terminal dipeptide from QbsE. Both CysO and QbsE are similar to prokaryotic sulfur carrier proteins such as ThiS and MoaD, containing the beta-grasp ubiquitin-like fold.	6.6805e-42

Protein sequences

>NC_020990.1|WP_037629993.1|2098426_2099029_-|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase
MTRLILATRNTGKITELRAILADAGLSHELVGADAYPEIPDVKETGVTFAENALLKAHALAQATGLPAVADDSGLCVEVLGGAPGIFSARWAGRHGDDQANLDLLLAQLSDIDDPHRAAYFACAAALALPDGTERVVEGRLTGTLRHAPAGTHGFGYDPILQPDGETRTCAELTPPEKNAISHRGKAFRALAPIVQELLG
>NC_020990.1|WP_003950572.1|2096557_2098057_+|glycine-betaine/L-proline-transporter-ProP
MADTGPQTGGDPEAVKRHPRLFRAARQRRNPRLRRSDITVTDERAVKRAVKAASLGNAMEWFDFGIYSYLAVTIGHVFFPSGNDTVQLLSSFATFAVAFLVRPLGGMFFGPMGDRLGRKKVLALTMILMALGTFCIGLIPSYASIGFWAPLLLILFRLVQGFSTGGEYGGASTFIAEYAPDKRRGFFGSFLELGTLLGYTGAAGLVTALYAVLDDGAMESWGWRIPFLVAGPLGFVGIYLRLKLDETPAFQKLEDGTSAHASEAADGVETTHKGDLAKIFRRYWPSLILCIALVGAYNITDYMLLSYMPTYLSDEMGYDESHGLLILIGVMVLLMLIINQVGKLSDRFGRKPLLMTGMISFFFLSIPSFLLVKQGSLLAVSGGMLMLGLSLVCLLGTMSAALPALFPTPVRYGSLSVGYNLSASLFGGTTPLVITGLIGLTGDDMMPAYYAMAASLVGIIAVACMKETAHRPLAGSPPSVATEEEAREILDAQSPDPKF
>NC_020990.1|WP_003950573.1|2095917_2096385_+|thioredoxin-dependent-thiol-peroxidase
MSERLKPGDTAPAFTLPDADGNEVSLASHQGRKVIVYFYPAALTPGCTKQACDFTDNLDALASAGYDVIGVSPDKPEKLAKFREKEDLKVTLVGDPSKETLAAYGAFGEKKLYGKTVTGVIRSTVVVGEDGTVEHAFYNVKATGHVAKIMRDLGV
>NC_020990.1|WP_010642676.1|2095416_2095770_-|DUF3618-domain-containing-protein
MGTDDDGGSAVSDARTPAQIEADIKRRRDTLAETLDEIGVRVHPKTIVGDAKAQVASRVDATLGRAYVGVNRALSQVRSGFTREDGSVRPERVIPVALVAVGIVGLVVASSRRDSGK
>NC_020990.1|WP_023417316.1|2094997_2095300_-|co-chaperone-GroES
MLHDRVLVRTDIPEGERRSTGGIVIPATAAVGRRLGWAEVVAVGQNVRAVEPGDRVLYDPEDRAEVEVRGVAYVLMRERDLHAVAADRFEGSEDATGLYL
>NC_020990.1|WP_003950576.1|2094520_2094841_-|quaternary-ammonium-compound-efflux-SMR-transporter-SugE
MAWILLLVAGLLEVGWSIGMKYTEGFTRLWPSVFTAAGIVASMVLLAQAARTLPIGTAYGVWVGIGAAGAAILGMLVLGEPATAARIFFVCLLIVAVVGLKLTSGH
>NC_020990.1|WP_015507166.1|2092119_2094450_+|penicillin-binding-protein
MSEERQQPDGADEERQRWPGWEERDPDAGGPRKHGIRRFLPGWRLVLGSFLALVVLVCGGFLVGYLLVDIPAANAAATQQSNVYLYADGTQLASDGDVNRENISLSDLPKPVRHAVLAAEDRDFYTGSAVDPQAMIRGAWKTVTGKGKQSGSTITQQYVKNYYLDQDQTVTRKAKEFFIAIKLDRETSKDEILEGYLNTSYFGRNAYGIQAAAQAYYGIDARDLNTAQGAYLASLLNAPSAYDVIAQPANRSRAEARWNYVLDGMVKENWLTESGRARLSFPTPDEQHLPRGLSGQRGYLVQAVDAYLVSHGVVSEAQLAKGGHRITTTLVKGHQDALVKAVDDKLISKLDKKERKADRNVRAGGVAIDPDTGKVLAMYGGIDYTEQYVNNATRRDYQVGSTFKPFVLTAALQHKARTQDGRTINPNARYDGTNKRRVEGWTGGPYEPENEDERDYGDITLKVATDRSVNAVYAQLAVDVGPEKVKDTAIALGLPKATPDLQPYPSIALGTATASVLDMAEAYATLADHGRHRSHRLVQEISHLGEKLELPQERVQGAVTRRAADTTTEVLRSVVRGGTGMAAREAGRPAAGKTGTAEEDTAAWFAGYTPDLTTVIAVMGQDPKSGAHTPLYGALGLPRINGGGPPAEIWAQFTRAALAGQPVRDFQLDADRSAEDSPTASPSETGAASRGPRDPDASGEPDGDGSSSREPGGDSPSESGGDTEVPPGMEEDPGRNGDPAPPGEPAPDTPAPAPAREPRETLAPLATPDLDPPQAG
>NC_020990.1|WP_003950578.1|2091075_2091897_-|ABC-transporter-permease
MAHGPGRAALYAAVAAKGFRRYATYRAATLAGIFTNTVFGVILAQTYLALWAERPGLGGYDQAQALTFVWIGQSLHMAVAAMGGGSEEELMERIRSGDIAVDLYRPVDLQLWWLAQDAGRACFQLFARGALPLAFGALVFDLALPASPGTWIAFLTAVALGLLVSFGIRYLVALSAFWLLDGAGVGQLAWLVGMFFSGMLLPLNVFPGLLGEVARVLPWSSILQLPADVLLGVHTGTGLLGVYAFQLAWAVALLAAGRALQSLATRRVVVQGG
>NC_020990.1|WP_003950579.1|2090213_2091083_-|transporter
MADPAAPPRPAPDPVDARFGSPLTEGLRTYRLVVAMWVRSTLTYRASFAMALCVAVAANGLDFVAILLMFSHVDRLGGFTLGEVAFLYGTSATAFGLAHLTVGSMDRLGRRIRDGSLDTLLVRPVPVLAQLAADRFALRRLGRITQGALVLAYALTVLEIDWTATRLLMVPMMLVSGAALFGALFVAGAVFQFYAQDAAEVQNAFTYGGTTLLQYPPTVFTRELVASVTFVLPLAFVNWVPASYVLDRPLPLGLPVQAAFAPPLVAAVCCVAAGLLWRVGLRAYRSTGS
>NC_020990.1|WP_008405025.1|2089158_2090169_-|ATP-binding-cassette-domain-containing-protein
MDATERPVADLPAQRDGQEVIHLDRVEKVFEVRRRAGLLRREKREVRAVDGLSFSVGRGEVVGFVGPNGAGKSTTIKMLTGILTPSAGTLRVAGVEPARDRARLARRIGVVFGQRTTLWWDLPLLDSYQLIHRMYRVPDARYRENLDRCVELLGLGDLLDVPVRQLSLGQRMRGDIAAALLHDPEVLYLDEPTIGLDVVSKANVRRFLADLNAERGTTVLLTTHDLTDIEQLCRRVMVIDHGRLMYDGEVAGLHRIAEVERTLVVDLATELAPIALESARTVKVEGPRQWLAFPAGQPAAPIVAEIAAGWPLVDLSLREPDIEDVISLMYAGRSAG
>NC_020990.1|WP_003950570.1|2099400_2099784_-|hypothetical-protein
MPTSRRLATATAGAALLVPLLLGCGALEKAADCVRTADRIADSVADLQRAADGAAEDPQQASEALDRIDKNVDDIQKDTGDADVKKAVDHLDTAVGNVRASLEKGDEVPDVSPVVDAAGELTKVCTP
>NC_020990.1|WP_003950569.1|2099916_2100642_-|ribonuclease-PH
MDRIDGRTPAQLRPLTIERSWSKHAEGSVLVAFGDTKVLCTASFTEGVPRWRKGSGEGWVTAEYSMLPRATNTRGDRESVRGKIGGRTHEISRLIGRSLRAVIDYKALGENTIVLDCDVLQADGGTRTAAITGAYVALADAISWAQGKKIIKPGRKPLTGSVAAVSVGIVGSTPLLDLCYEEDVRAETDMNVVCTGDGRFVEVQGTAEGAPFDRTELDALLDLGATGCADLTKGQLAALAE
>NC_020990.1|WP_003950568.1|2100752_2100986_-|PTS-transporter-subunit-EIIB
MASKAEKIVAALGGIDNIDEVEGCITRLRTEVHDPSKVDEAALKAAGAHGVVKMGTAVQVVIGTDADPIAADIEDLM
>NC_020990.1|WP_003950567.1|2101152_2102439_+|PTS-transporter-subunit-EIIC
MSTANEALPRKRWWNSLFQGLQKMGRSLQLPIAVLPAAGILNRLGQPDVFGDEGLGWTGVAKVMAGAGGGLLDPNIGLPLLFCVGVAIGMAKKADGSTALAAVAGFLVYYNVLQQFPKDCPADTKDVLAGCQAADGSVVAYEYQNPGVFGGIVIGLLAAYFWQRFHRTRLVDWLGFFNGRRLVPIIMAFVAIAFAAICLWIWPPIGDGLESFSDWLIGLGSWGAGIFGVANRALLVIGLHQFLNVPIWFQFGSYTTPDGQVVHGDITRFLAGDPTAGQFTSGFFPIMMFALPAAALAIAHSAKPHRRKEVGGLMLSVGLTSFVTGITEPLEYSFLFIAPVLYVIHALLTGVSMAVTWAFGVHDGFSFSAGLIDYVINWGLATKPWLIIPIGLAFAVVYYVVFRVLITKLDLKTPGREDEEEVEDTTKA
>NC_020990.1|WP_003950566.1|2102444_2102828_-|hypothetical-protein
MPRTPAPRPSASPALDARVALLRRAAHADPRLEGVLLYGSWTTGEADAYSDTDHWLTPSRAAEDDLPAADLARYTATTAPLEAAALRAAARASWQWSRELAAEAHGRWGTPVPEALHARIAGLLARD
>NC_020990.1|WP_003950565.1|2103041_2103791_-|MBL-fold-metallo-hydrolase
MKLTVVGCSGSFPSAESACSSYLVEADGFQLLLDMGNGALGELQRHTGLYDLDAVFLSHLHADHCIDMCAYFVARYYRHGDGPCDALPVYGPEGTQQRLITAYGDSSAEHMPEVFDFRTLKEDAFDLGPFRIRTVRVPHPVEAYAIRVEHDGRSLTYSGDTGPCAELDALAAGTDLYLCEAAFTHGKENIPDLHLNGREAGESAQRAGAGRLLLTHIPPWTDPRTNLTDAREVYDGPAALAEPGVTYTV
>NC_020990.1|WP_003950564.1|2104071_2105022_-|cysteine-synthase
MRYDSPLAAVGNTPLVRLPRLSPSDDVRIWAKLEDRNPTGSVKDRPALHMVEQAEKDGRLTPGCTILEPTSGNTGISLAMAARLKGYRIVCVMPENTSQERRDLLAMWGAEIVSSPAAGGSNTAVRVAKELAAEHPDWVMLYQYGNPDNAGAHYATTGPEILADLPSVTHFVAGLGTTGTLMGVGRYLREQKPGIAIVAAEPRYDDVVYGLRNLDEGFVPELYDASVLTSRFSVGSADAVSRTRELLQQEGIFAGVSTGAALHAAIGVGRKAVKAGESADIVFVVADGGWKYLSTGVYTAATTEEAIETLHGQLWA
>NC_020990.1|WP_003950563.1|2105021_2105306_-|MoaD/ThiS-family-protein
MAIEVRIPTILRTYTDGAKTVEGSGTTLAELIDDLETRHAGIKERIVDGDQLRRFVNVYLNDEDVRFLDSIDTKVADGDNVTILPAVAGGSAAL
>NC_020990.1|WP_003950561.1|2105697_2106132_-|M67-family-metallopeptidase
MLTLTQALHDQIVAHARADHPDEACGIVAGPAGSGRPERFIPMLNAARSPTFYEFDSMDLLKLYRELDDRDEEPVIVYHSHTATEAYPSRTDVTYANEPGAHYVLVSTADTDDAGPFQFRSFRIVDGEITEEDVQVVAAYPAAG
>NC_020990.1|WP_003950560.1|2106232_2107678_-|amino-acid-permease
MSSTQVDTVSDGEPGPGRGGPSTPHGGEGYQRGLGARQIQMIAIGGAIGTGLFLGAGKAISKAGPSLILAYAIAGLVIFFIMRALGELLMYRPVSGSFSEYAREFIGPFAGFVTGWTYWLFWVVTGITEVTAAAQYMTYWFDVPQWVSALLFTIILYGANLISVKIFGELEFWFSMVKVTAIVGMILICVGILTLGFSDAGDTATVAHLWNQGGFFPEGIGGTLMTLQIVMFAFLAVELVGVTAGESKDPEKTLPKAINTVPWRIAVFYVGALVMILSVVPWTEFQPGISPFVAAFEKMGLGVGAAIVNFVVLTAALSSCNSGMYSTGRMLRDLALNGQGPKFFTRLTRSGTPLVGTTFSAALMMVGVWINYQWPGEAFNYVVSFATISGMWAWVMILVCQIRYRAKADRGELPVSSFRAPGAPFTSWFALCFLALVVVMMGIDPDTRISLYCAPLWAAILLVSYRVLRARDPQNAAFAKR

Crispr_ID: NC_020990_8

• CRISPR_ID: NC_020990_8
• CRISPR_location: 2112521-2112609
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_8

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCTGT	CRISPRCasFinder

spacers of NC_020990_8

>8.1|2112546|39|NC_020990|CRISPRCasFinder
TGTGTGCCGGGCTCCCTCTCGACCGTGCCGGTCAAAGAC

CRISPR arrays and Neighbor proteins around NC_020990_8

CRISPR arrays

The CRISPR arrays of NC_020990_8

>merge|NC_020990|8|2112521-2112609|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGTTGTGTGCCGGGCTCCCTCTCGACCGTGCCGGTCAAAGACTGGCCTCAAACGCCGGCCGGGCTGT

>NC_020990|8|7|2112521-2112609|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGT	TGTGTGCCGGGCTCCCTCTCGACCGTGCCGGTCAAAGAC
TGGCCTCAAACGCCGGCCGGGCTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_041826592.1|2121443_2122880_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NC_020990.1|WP_003950553.1|2113679_2116085_-|M6-family-metalloprotease-domain-containing-protein	unknown	unknown	gnl|CDD|368494
NC_020990.1|WP_003950556.1|2110447_2111776_+|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|236426
NC_020990.1|WP_003950552.1|2116531_2116792_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950560.1|2106232_2107678_-|amino-acid-permease	unknown	unknown	gnl|CDD|224038
NC_020990.1|WP_003950564.1|2104071_2105022_-|cysteine-synthase	unknown	unknown	gnl|CDD|273463
NC_020990.1|WP_015507172.1|2117648_2118983_-|RDD-family-protein	unknown	unknown	gnl|CDD|377640
NC_020990.1|WP_008406550.1|2109895_2110210_-|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl|CDD|178809
NC_020990.1|WP_015507173.1|2119855_2121280_-|FAD-binding-protein	unknown	unknown	gnl|CDD|273050
NC_020990.1|WP_015507171.1|2116891_2117569_-|RDD-family-protein	unknown	unknown	gnl|CDD|377640
NC_020990.1|WP_003950546.1|2124266_2124737_+|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224439
NC_020990.1|WP_003950554.1|2113218_2113557_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950565.1|2103041_2103791_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293802
NC_020990.1|WP_008414233.1|2119294_2119771_+|SsgA-family-sporulation/cell-division-regulator	unknown	unknown	gnl|CDD|377399
NC_020990.1|WP_003950561.1|2105697_2106132_-|M67-family-metallopeptidase	unknown	unknown	gnl|CDD|163701
NC_020990.1|WP_015507168.1|2108049_2109159_-|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380492
NC_020990.1|WP_003950547.1|2122970_2124134_-|4-hydroxyphenylpyruvate-dioxygenase	unknown	unknown	gnl|CDD|273528
NC_020990.1|WP_003950563.1|2105021_2105306_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340594
NC_020990.1|WP_015507169.1|2109293_2109896_-|DUF2017-domain-containing-protein	unknown	unknown	gnl|CDD|378185
NC_020990.1|WP_003950555.1|2111884_2112475_+|nicotinamidase	unknown	unknown	gnl|CDD|238493

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003950553.1|2113679_2116085_-|M6-family-metalloprotease-domain-containing-protein	gnl|CDD|368494	pfam05547, Peptidase_M6, Immune inhibitor A peptidase M6. The insect pathogenic Gram-positive Bacillus thuringiensis secretes immune inhibitor A, a metallopeptidase, which specifically cleaves host antibacterial proteins. A homolog of immune inhibitor A, PrtV, has been identified in the Gram-negative human pathogen Vibrio cholerae.	0
NC_020990.1|WP_003950556.1|2110447_2111776_+|nicotinate-phosphoribosyltransferase	gnl|CDD|236426	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated.	0
NC_020990.1|WP_015507172.1|2117648_2118983_-|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	1.56697e-23
NC_020990.1|WP_003950560.1|2106232_2107678_-|amino-acid-permease	gnl|CDD|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NC_020990.1|WP_003950564.1|2104071_2105022_-|cysteine-synthase	gnl|CDD|273463	TIGR01136, Cysteine_synthase, cysteine synthase. This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family].	5.57894e-139
NC_020990.1|WP_008406550.1|2109895_2110210_-|ATP-dependent-Clp-protease-adapter-ClpS	gnl|CDD|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	1.58339e-41
NC_020990.1|WP_015507173.1|2119855_2121280_-|FAD-binding-protein	gnl|CDD|273050	TIGR00387, Glycolate_oxidase_subunit_glcD., glycolate oxidase, subunit GlcD. This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other].	1.3321e-138
NC_020990.1|WP_015507171.1|2116891_2117569_-|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	1.53759e-26
NC_020990.1|WP_003950546.1|2124266_2124737_+|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	9.3337e-27
NC_020990.1|WP_041826592.1|2121443_2122880_+|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	4.85549e-09
NC_020990.1|WP_003950565.1|2103041_2103791_-|MBL-fold-metallo-hydrolase	gnl|CDD|293802	cd07716, RNaseZ_short-form-like_MBL-fold, uncharacterized bacterial subgroup of Ribonuclease Z, short form; MBL-fold metallo-hydrolase domain. The tRNA maturase RNase Z (also known as tRNase Z or 3' tRNase) catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Two forms of RNase Z exist in eukaryotes, one long (ELAC2) and one short form (ELAC1), the former may have resulted from a duplication of the shorter enzyme. Only the short form exists in bacteria. Members of this bacterial subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	4.14449e-84
NC_020990.1|WP_008414233.1|2119294_2119771_+|SsgA-family-sporulation/cell-division-regulator	gnl|CDD|377399	pfam04686, SsgA, Streptomyces sporulation and cell division protein, SsgA. The precise function of SsgA is unknown. It has been found to be essential for spore formation, and to stimulate cell division.	1.39691e-40
NC_020990.1|WP_003950561.1|2105697_2106132_-|M67-family-metallopeptidase	gnl|CDD|163701	cd08070, MPN_like, Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding). This family contains archaeal and bacterial MPN (also known as Mov34, PAD-1, JAMM, JAB, MPN+)-like domains. These domains contain the signature JAB1/MPN/Mov34 metalloenzyme (JAMM) motif, EXnHS/THX7SXXD, which is involved in zinc ion coordination and provides the active site for isopeptidase activity for the release of ubiquitin from ubiquitinated proteins (thus having deubiquitinating (DUB) activity) that are tagged for degradation. The JAMM proteins likely hydrolyze ubiquitin conjugates in a manner similar to thermolysin, in which the zinc-polarized aqua ligand serves as the nucleophile, compared with the classical DUBs that do so with a cysteine residue in the active site.	1.90861e-37
NC_020990.1|WP_015507168.1|2108049_2109159_-|amino-acid-ABC-transporter-substrate-binding-protein	gnl|CDD|380492	cd06268, PBP1_ABC_transporter_LIVBP-like, periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.	7.56688e-37
NC_020990.1|WP_003950547.1|2122970_2124134_-|4-hydroxyphenylpyruvate-dioxygenase	gnl|CDD|273528	TIGR01263, 4-hydroxyphenylpyruvate_dioxygenase, 4-hydroxyphenylpyruvate dioxygenase. This protein oxidizes 4-hydroxyphenylpyruvate, a tyrosine and phenylalanine catabolite, to homogentisate. Homogentisate can undergo a further non-enzymatic oxidation and polymerization into brown pigments that protect some bacterial species from light. A similar process occurs spontaneously in blood and is hemolytic (see . In some bacterial species, this enzyme has been studied as a hemolysin. [Energy metabolism, Amino acids and amines].	9.18263e-179
NC_020990.1|WP_003950563.1|2105021_2105306_-|MoaD/ThiS-family-protein	gnl|CDD|340594	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins. CysO, also termed 9.5 kDa culture filtrate antigen cfp10A, together with CysM (Cysteine synthase M), forms a protein complex CysM-CysO that represents a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. The replacement of the acetyl group of O-acetylserine by CysO thiocarboxylate to generate a protein-bound cysteine is catalyzed by CysM in a pyridoxal 5?-phosphate (PLP)-dependent manner. The family also includes QbsE that functions as the sulfide donor for the biosynthesis of thioquinolobactin in Pseudomonas fluorescens. A JAMM motif protein QbsD catalyzes removal of the carboxy-terminal dipeptide from QbsE. Both CysO and QbsE are similar to prokaryotic sulfur carrier proteins such as ThiS and MoaD, containing the beta-grasp ubiquitin-like fold.	6.6805e-42
NC_020990.1|WP_015507169.1|2109293_2109896_-|DUF2017-domain-containing-protein	gnl|CDD|378185	pfam09438, DUF2017, Domain of unknown function (DUF2017). This is an alpha-helical domain found in gene neighborhoods that contain genes encoding ubiquitin, cysteine synthases and JAB peptidases.	1.36496e-56
NC_020990.1|WP_003950555.1|2111884_2112475_+|nicotinamidase	gnl|CDD|238493	cd01011, nicotinamidase, Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is also called pyrazinamidase, because in converts the tuberculosis drug pyrazinamide (PZA) into its active form pyrazinoic acid (POA).	9.1451e-71

Protein sequences

>NC_020990.1|WP_003950555.1|2111884_2112475_+|nicotinamidase
MRRALIVVDVQNDFCEGGSLAVTGGAEVAAAITEHLDGPGRELYDHVVATRDHHIEPGDHFSARPDFRDSWPVHCVAGTEGAGFHPAFAPALVSGAVEAVFDKGAYSAAYSGFEGVDENGVGLADWLRGQGVTDVDVVGLATDYCVRATALDALAAGFGTRVLLDLAAGVAPDSVATTVTELREAGAVLTGKPAQT
>NC_020990.1|WP_003950556.1|2110447_2111776_+|nicotinate-phosphoribosyltransferase
MRLPVEVPSTALFTDHYELTMLQAALAAGTADRPCVFEVFTRKLPEGRRYGVLAGVGRVLDAVEHFRFEPAQLDHLRAHDVVDEATLDYLAGYRFSGTISGYPEGEVYFPGSPVLRVEGTFAECVLLETVILSILNHDSAIAAAASRMSSAAAGRPLIEMGARRTHELAAVAASRAAYIGGFTTTSDLAAGFRYDIPTTGTSAHAFTLLHDNERDAFEAQVAALGRGTTLLVDTYDVQEAVRTAVEVAGPELGAVRIDSGDLLLVAHRVRDQLDRLGARDTRIVVTSDLDEYAIASLAAAPVDAYGVGTQLVTGSGHPTCSMVYKLVARARSTEPGAPLEPVAKKSLGGKTSLGGRKWAARRRDAEGVAEAEVVGTGPVPPELADAQLLVELVRDGEVVGREPMDVARERHAAARAALPLSATQLSKGEPVIPTEYVAPQPG
>NC_020990.1|WP_008406550.1|2109895_2110210_-|ATP-dependent-Clp-protease-adapter-ClpS
MGRVSVSPAETEQPAAAEETFAVPEPDLPWVTLVHNDPVNLMSYVAYVFQAYFGYSKEKANKLMLDVHHKGRAVVSSGSREEMERDVQAMHGYGLWATLQQDRA
>NC_020990.1|WP_015507169.1|2109293_2109896_-|DUF2017-domain-containing-protein
MAGYFEPTEKGAAATLDAVEISIIRSLAVQLLELIGPGDDHLGDDPLAELFAEGPSEAPTDPVLRRLFPDAYADPATAATAQEAEELRARSAEFRRFTENDLRAAKRESALLVVRTLDAVPVDSEGGGTVELTPDQSRQWIGALNDLRLAIAARLDLRDESDTDELFQLPDSDPRKPMVIAQLWLAGLQESLIETLTAGG
>NC_020990.1|WP_015507168.1|2108049_2109159_-|amino-acid-ABC-transporter-substrate-binding-protein
MSPPPPHTTPESGPPPVPLGALVPLTRPGWTEAGRHLLAGLELGVDEVNAAGGIGGRPLELLVRDTAADPGRAEAAVEELAGLGVAAVAGEYHSVVARAAAVRAEALGVPFLCSSAVLDALTEEPATWVARLAPAQSHGWRSYAGFLLAAGHRRIAVARQASLYWETGTRILRDHLGQRGGSVTELDADALTPRELCDALAEDGATALLLLAGTPQPAVPLVRAVRADRRLDGVLVGAPAGQPEFPRWLAALGADGAGVPFLRYLPERPGPPAVRVGEALRARLGEEPSFVAYEGWDTVAVLAGALRTYGTGRADVARAWEGGAVVGTRGEIRFSRLPGIGVRQWVWPPVQVADRDPAEPGRFRVLHQG
>NC_020990.1|WP_003950560.1|2106232_2107678_-|amino-acid-permease
MSSTQVDTVSDGEPGPGRGGPSTPHGGEGYQRGLGARQIQMIAIGGAIGTGLFLGAGKAISKAGPSLILAYAIAGLVIFFIMRALGELLMYRPVSGSFSEYAREFIGPFAGFVTGWTYWLFWVVTGITEVTAAAQYMTYWFDVPQWVSALLFTIILYGANLISVKIFGELEFWFSMVKVTAIVGMILICVGILTLGFSDAGDTATVAHLWNQGGFFPEGIGGTLMTLQIVMFAFLAVELVGVTAGESKDPEKTLPKAINTVPWRIAVFYVGALVMILSVVPWTEFQPGISPFVAAFEKMGLGVGAAIVNFVVLTAALSSCNSGMYSTGRMLRDLALNGQGPKFFTRLTRSGTPLVGTTFSAALMMVGVWINYQWPGEAFNYVVSFATISGMWAWVMILVCQIRYRAKADRGELPVSSFRAPGAPFTSWFALCFLALVVVMMGIDPDTRISLYCAPLWAAILLVSYRVLRARDPQNAAFAKR
>NC_020990.1|WP_003950561.1|2105697_2106132_-|M67-family-metallopeptidase
MLTLTQALHDQIVAHARADHPDEACGIVAGPAGSGRPERFIPMLNAARSPTFYEFDSMDLLKLYRELDDRDEEPVIVYHSHTATEAYPSRTDVTYANEPGAHYVLVSTADTDDAGPFQFRSFRIVDGEITEEDVQVVAAYPAAG
>NC_020990.1|WP_003950563.1|2105021_2105306_-|MoaD/ThiS-family-protein
MAIEVRIPTILRTYTDGAKTVEGSGTTLAELIDDLETRHAGIKERIVDGDQLRRFVNVYLNDEDVRFLDSIDTKVADGDNVTILPAVAGGSAAL
>NC_020990.1|WP_003950564.1|2104071_2105022_-|cysteine-synthase
MRYDSPLAAVGNTPLVRLPRLSPSDDVRIWAKLEDRNPTGSVKDRPALHMVEQAEKDGRLTPGCTILEPTSGNTGISLAMAARLKGYRIVCVMPENTSQERRDLLAMWGAEIVSSPAAGGSNTAVRVAKELAAEHPDWVMLYQYGNPDNAGAHYATTGPEILADLPSVTHFVAGLGTTGTLMGVGRYLREQKPGIAIVAAEPRYDDVVYGLRNLDEGFVPELYDASVLTSRFSVGSADAVSRTRELLQQEGIFAGVSTGAALHAAIGVGRKAVKAGESADIVFVVADGGWKYLSTGVYTAATTEEAIETLHGQLWA
>NC_020990.1|WP_003950565.1|2103041_2103791_-|MBL-fold-metallo-hydrolase
MKLTVVGCSGSFPSAESACSSYLVEADGFQLLLDMGNGALGELQRHTGLYDLDAVFLSHLHADHCIDMCAYFVARYYRHGDGPCDALPVYGPEGTQQRLITAYGDSSAEHMPEVFDFRTLKEDAFDLGPFRIRTVRVPHPVEAYAIRVEHDGRSLTYSGDTGPCAELDALAAGTDLYLCEAAFTHGKENIPDLHLNGREAGESAQRAGAGRLLLTHIPPWTDPRTNLTDAREVYDGPAALAEPGVTYTV
>NC_020990.1|WP_003950554.1|2113218_2113557_-|hypothetical-protein
MAAGGFVRMPGGSVVVALSLPAPTPGGGRGEQRVRVLVHAKNRARALTRLRNLGLRAVYLRGNGAPPTPDEITAVLHHPDGLIWRAAAPAPAGDLSVSRAPELWRPIRALLA
>NC_020990.1|WP_003950553.1|2113679_2116085_-|M6-family-metalloprotease-domain-containing-protein
MSRHRRAFRATALSVAIAAIGATTAAVGTAQAADRPAGDDQAVERRDPAPAKGHVEHNLEGPFSEKQEKQRGEALRQLISGDKKASQRDGSRVLRLDDGKYVELGREKTDQIFTILVEFGDKVDDTTMYDPDGPEGPEEPVVKYGGEPGPLHNQIAEPDRKNDNSTDWKADFSRDHFQDLYFSTEKNKESVKKYYEKQSSGRYSVDGEVTDWVKVDYNEARYGSNYCGDTNCANVWDVVRDGVNQWAADQKAAGRSDAEIKEQLAKYDTWDRYDFDGDGDFNEPDGYIDHFQIVHAGEDESAGGGAQGTDAIWAHRWYAYGTDAGKTGPAGNKAGGAQIGDTGIWVGDYTVQPENGGLGVFAHEYGHDLGLPDHYDTSGAGENSTAFWSLMSSGSWLGTGKTEIGNLPGDMTAWDKLQLGWLDYATAKAGTKSTHKLGVAEYNTKDKQALVVELPEKEVTTTITEPAEGSAQWWSDSGDDLKNTLTRPVDLTGRSAATLDLQGWWNIEENYDFLYTEVSTDGGANWTALDGTVDGKPLPRDGGDTPALHGVSDGYRALSFPLDAYAGQQIELRFRYQTDGGLAEPGFAADAISLTADGEELFADGAEDGDNGWTAKGFQRIGASFTQDYPQYYIAENRQYVSYDTTLKTGPYNFGWTSTRPDWVEHFPYQNGLLIWLWDTSQKDNNTGVHPGEGRVLPVDAHPKAEKWADGTIMRNRIQAYDAPFSWYPTQGFTLHQDGKPAKVKPKLGIPVFDDGFPGRYYDAANPTGSVKVTDTNTRITITKEPLSGKTITVKVGPSQK
>NC_020990.1|WP_003950552.1|2116531_2116792_+|hypothetical-protein
MARPTPAQYATGTATVVLATLALLLLTGTTGGAGVALIAAAALGLGLGAACAVARARPAAPAGTRDEAVRRHAGVAVPGGERGLRG
>NC_020990.1|WP_015507171.1|2116891_2117569_-|RDD-family-protein
MTTEPPPPGSGNSPDDDPFRKPPPSGAGSPYDPPPQGGGGGDPYGGNPYDNPPPPGGGGPYGPAGGGGPYGGDPLAGMPPLAPSGKRVLARVIDMIIVGVVVWLLSMLFNVGTWDSDVDNIDAGKSFGQSLIAAILYIAYDTILTARTGQTVGKRLLHLRVADLSNGATPSTQTSLIRAVVLWLPFAFCCACIWTIICGGWSFFDRPYKQGLHDKAAKTVEVTTG
>NC_020990.1|WP_015507172.1|2117648_2118983_-|RDD-family-protein
MSAPTPAPGDDRPRPAYYPDPSIPGYIRYWNGASWVPGTSRPAPAAGEPLPAPPPGSVPATPAPAEETGPVFLDEDPAAPSAEGPARDSAWGADPARQSGFGGAPDHRVSWGGPEPAVPDPRTGEPAAPAKPVEGTLTFRRPSGPVAPAARRETAGPSGLAQSPVDPRGTSAPATPTTPAPRQDPGTLPIRALPRTPAPATEQPAAPAVPQPRPAPAPAPVRQPAPVQQPAPVQPGWAQQLPAPAAPAAPAVPVAPARGDENVPVVPWKPPVEDPFLAAARAQAAARPAGLGRRLAARLVDTLVVGAVTAAAAVPLASAARDHLDAKIEAAKLSGRTVTVWLLDGTTAGYLAAVLAVLLLFGVVYEALPTAKWGRTLGKKLFGLRVQDIEEHDAPAFGAALRRWLVYSVSGVLVVGVAGVLWCLFDRPWRQCWHDKAARTFVAR
>NC_020990.1|WP_008414233.1|2119294_2119771_+|SsgA-family-sporulation/cell-division-regulator
MNTVVERELELRLVLSPERSIAVPARLVYAAADPFAVSVTFHLGSQNPVHWTFARELLVEGVFRPCGHGDVRIWPSKVGGRNVLLMALSSPDGDALLQAPSVAVSAWLDRTLTLVPPGTEHERLEMDAGLARLLEPAPADDLWRGDPWSEEAPGPDGE
>NC_020990.1|WP_015507173.1|2119855_2121280_-|FAD-binding-protein
MPEPQMPAPPAAEPPAPPGPTALLDRLREGLPAEAVLTDPDVTAAYAHDMASFCEAGKPAAVVLPRTTEQVQHVMRTATAFRVPVVPQGARTGLSGAANAVDGCLVLSLIKMDRVLEIDPVNRIAVTEPGVVNAVLSRAVEEHGLSYPPDPSSWETCTIGGNIGTASGGLCCVKYGVTAEYVLGLDVVLADGRLLTTGRRTAKGVAGYDLTRLFVGSEGSLGVVVKAVLALKPRPPRQLALAAEFPSAAAAGDAVCRIMAEGHTPSLLELMDRTTVRAVNAMARMGLPETTEALLLAAFDTPDPAADLAAVGALCEAAGATGVVPADTEAESELLLAARRMSLVALEAVKGTTMIDDVCVPRSRLAELLEGVEEIAARYDLTIGVCAHAGDGNTHPTVCFDATDADEARRARESFDAIMALGLELGGTITGEHGVGVLKKEWLARELGPTGVEVQRSLKAALDPLGLLNPGKLF
>NC_020990.1|WP_041826592.1|2121443_2122880_+|tetratricopeptide-repeat-protein
MARTPRPRLGQRVPGAPPPPAARRPRRRGPRLSAAVGVGLLLAGGGVVAVDRLGQDRAAPAPLTPAGRALAAAGAGRPAALADLAALIGERRERVRRAPADRASWAVLGAALAERAARSGAPGAYTEAERALQRALAQGGTPDVRALTGLAVLAAARQDWAGAVRWGEAARDRAPGRVGAYRVLLEAYPGTGDAEGADRALERLRKVRPGPVAEVAAAWVHRERGWREDAEATVYDAAARAATPAERAAALSRAGDLAWERGEAETALARYEGALRAEPEHDGAAAGRARALAGLGRSEEALTAWARARAAAPRPGYAVESGELLLALGRSAEAADHFSLARHQAAALARDGVRQEPVLGRLEADHGDPAEAVRLLTEEHRRHPGPAASGALGWALHKAGRSAEALPRLRAAVKDGPNTARPAYHLGMVHLALGERGAARRQLTRALRLAPQFSPLHAERARRELAALGEPAWGPPPA
>NC_020990.1|WP_003950547.1|2122970_2124134_-|4-hydroxyphenylpyruvate-dioxygenase
MAATSTNPQAPQSAPTTAREADPFPVKGMDAVVFAVGNAKQAAHYYSSAFGMKLVAYSGPENGSRETASYVLENGGARFVLTSVIKASTERGAFLESHVAAHGDGVVDLAIEVPDARAAYAYAVEHGATGLEEPHEVKDEHGTVVLAAIATYGKTRHTLVERSGYSGPYLPGYVAADPIVAPPAKRTFQAIDHCVGNVELGKMNEWVAFYNKVMGFTNMKEFIGDDIATEYSALMSKVVADGTLKVKFPINEPAIAKKKSQIDEYLEFYGGAGVQHIALATNDIVQTVRTMRDAGVQFLDTPDSYYDTLGEWAGETRVPVETLRELKILVDRDEDGYLLQIFTKPVQDKPTVFFEMIERHGSMGFGKGNFKALFEAIEREQDRRGNL
>NC_020990.1|WP_003950546.1|2124266_2124737_+|Lrp/AsnC-family-transcriptional-regulator
MGIDELDGRLIVLLAREPRIGVLEASRRLGVARGTVQSRMDRLQSNGVIRGFGPDVDPAALGYRVTAFATLEIRQGQGPDVRAHLAQVPEVLELHTITGEGDMLCRLVARSNGDLQRVIDRVVGFDGIVRAATAIVMENPVPLRVIPLVEQAARET

Crispr_ID: NC_020990_9

• CRISPR_ID: NC_020990_9
• CRISPR_location: 2158391-2158661
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_020990_9

Consensus_repeat	Method
GATGGCCTCAAACGCCGGCCGGGCTAG	PILER-CR

spacers of NC_020990_9

>9.1|2158418|41|NC_020990|PILER-CR
GAATGATCCGGCTGAGCTCCGGCGCCCACGCCCGCGTCACA
>9.2|2158486|61|NC_020990|PILER-CR
AAGGGTGAGGCCCAGTCAGGAGCGACGCGGCCGGACCGGCCGCCGCAGGGCGCGCGTCACC
>9.3|2158574|61|NC_020990|PILER-CR
AAGGGTGAGGCCCGGTCAGGAGCGACGCGGCCGGACCGGCCGCCGCAGGGCGCGCGTCACC

CRISPR arrays and Neighbor proteins around NC_020990_9

CRISPR arrays

The CRISPR arrays of NC_020990_9

>merge|NC_020990|9|2158391-2158661|PILER-CR
GATGGCCTCAAACGCCGGCCGGGCTGGGAATGATCCGGCTGAGCTCCGGCGCCCACGCCCGCGTCACAGATGGCCTCAAGCGCCGGCCGGGCTAGAAGGGTGAGGCCCAGTCAGGAGCGACGCGGCCGGACCGGCCGCCGCAGGGCGCGCGTCACCGATGGCCTCAAGCGCCGGCCGGGCTAGAAGGGTGAGGCCCGGTCAGGAGCGACGCGGCCGGACCGGCCGCCGCAGGGCGCGCGTCACCGATGGCCTCAAACGCCGGCCGGGCTTG

>NC_020990|9|3|2158391-2158661|PILER-CR
GATGGCCTCAAACGCCGGCCGGGCTGG	GAATGATCCGGCTGAGCTCCGGCGCCCACGCCCGCGTCACA
GATGGCCTCAAGCGCCGGCCGGGCTAG	AAGGGTGAGGCCCAGTCAGGAGCGACGCGGCCGGACCGGCCGCCGCAGGGCGCGCGTCACC
GATGGCCTCAAGCGCCGGCCGGGCTAG	AAGGGTGAGGCCCGGTCAGGAGCGACGCGGCCGGACCGGCCGCCGCAGGGCGCGCGTCACC
GATGGCCTCAAACGCCGGCCGGGCTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003950513.1|2154890_2155724_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_020990.1|WP_003950507.1|2162072_2162354_-|DNA-binding-protein-HU-1	unknown	unknown	gnl|CDD|259859
NC_020990.1|WP_015507192.1|2168580_2169696_-|uroporphyrinogen-III-synthase	unknown	unknown	gnl|CDD|235981
NC_020990.1|WP_003950501.1|2169871_2170933_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507188.1|2150134_2152039_-|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224991
NC_020990.1|WP_015507189.1|2159507_2160080_-|YqgE/AlgH-family-protein	unknown	unknown	gnl|CDD|234694
NC_020990.1|WP_003950515.1|2152035_2152932_-|dehydrogenase	unknown	unknown	gnl|CDD|366378
NC_020990.1|WP_003950506.1|2162760_2164191_-|NAD-dependent-malic-enzyme	unknown	unknown	gnl|CDD|223358
NC_020990.1|WP_003950512.1|2155720_2156677_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_020990.1|WP_015507187.1|2143438_2143981_-|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|378696
NC_020990.1|WP_003950519.1|2145593_2147375_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223989
NC_020990.1|WP_003950520.1|2144161_2145475_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_020990.1|WP_003950505.1|2164690_2167078_-|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl|CDD|226482
NC_020990.1|WP_003950510.1|2159151_2159445_-|DUF3039-domain-containing-protein	unknown	unknown	gnl|CDD|378609
NC_020990.1|WP_003950514.1|2153251_2154889_-|beta-N-acetylhexosaminidase	unknown	unknown	gnl|CDD|119333
NC_020990.1|WP_015507191.1|2167971_2168580_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NC_020990.1|WP_003950508.1|2160430_2161771_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|236486
NC_020990.1|WP_003950504.1|2167202_2167790_-|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|378696
NC_020990.1|WP_003950511.1|2156708_2158013_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270450
NC_020990.1|WP_003950518.1|2147840_2150138_-|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|132240

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003950513.1|2154890_2155724_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	2.45441e-79
NC_020990.1|WP_003950507.1|2162072_2162354_-|DNA-binding-protein-HU-1	gnl|CDD|259859	cd14435, SPO1_TF1_like, Bacteriophage SPO1-encoded TF1 binds and bends DNA. This group contains proteins related to bacillus phage SPO1-encoded transcription factor 1 (TF1), a type II DNA-binding protein related to the DNA sequence specific (IHF) and non-specific (HU) domains. Type II DNA-binding proteins bind and bend DNA as dimers. Like IHF, TF1 binds DNA specifically and bends DNA sharply. Bacteriophage SPO1-encoded TF1 recognizes SPO1 phage DNA containing 5-(hydroxymethyl)-2'-deoxyuridine as opposed to thymine, Related family members includes integration host factor (IHF) and HU, also called type II DNA-binding proteins (DNABII), which are small dimeric proteins that specifically bind the DNA minor groove, inducing large bends in the DNA and serving as architectural factors in a variety of cellular processes such as recombination, initiation of replication/transcription and gene regulation. IHF binds DNA in a sequence specific manner while HU displays little or no sequence preference. IHF homologs are usually heterodimers, while HU homologs are typically homodimers (except HU heterodimers from E. coli and other enterobacteria). HU is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups).	9.32606e-39
NC_020990.1|WP_015507192.1|2168580_2169696_-|uroporphyrinogen-III-synthase	gnl|CDD|235981	PRK07239, PRK07239, bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; Validated.	3.10948e-173
NC_020990.1|WP_015507188.1|2150134_2152039_-|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl|CDD|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	1.17976e-54
NC_020990.1|WP_015507189.1|2159507_2160080_-|YqgE/AlgH-family-protein	gnl|CDD|234694	PRK00228, PRK00228, YqgE/AlgH family protein.	1.79008e-67
NC_020990.1|WP_003950515.1|2152035_2152932_-|dehydrogenase	gnl|CDD|366378	pfam00941, FAD_binding_5, FAD binding domain in molybdopterin dehydrogenase.	1.14535e-44
NC_020990.1|WP_003950506.1|2162760_2164191_-|NAD-dependent-malic-enzyme	gnl|CDD|223358	COG0281, SfcA, Malic enzyme [Energy production and conversion].	4.78232e-170
NC_020990.1|WP_003950512.1|2155720_2156677_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.76791e-65
NC_020990.1|WP_015507187.1|2143438_2143981_-|CGNR-zinc-finger-domain-containing-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	1.1624e-18
NC_020990.1|WP_003950519.1|2145593_2147375_-|DEAD/DEAH-box-helicase	gnl|CDD|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	8.9197e-59
NC_020990.1|WP_003950520.1|2144161_2145475_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.3122e-57
NC_020990.1|WP_003950505.1|2164690_2167078_-|UvrD-helicase-domain-containing-protein	gnl|CDD|226482	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only].	4.53417e-61
NC_020990.1|WP_003950510.1|2159151_2159445_-|DUF3039-domain-containing-protein	gnl|CDD|378609	pfam11238, DUF3039, Protein of unknown function (DUF3039). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.92152e-35
NC_020990.1|WP_003950514.1|2153251_2154889_-|beta-N-acetylhexosaminidase	gnl|CDD|119333	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. This GH20 domain family includes an N-acetylglucosamidase (GlcNAcase A) from Pseudoalteromonas piscicida and an N-acetylhexosaminidase (SpHex) from Streptomyces plicatus. SpHex lacks the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NC_020990.1|WP_015507191.1|2167971_2168580_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.00594e-21
NC_020990.1|WP_003950508.1|2160430_2161771_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl|CDD|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NC_020990.1|WP_003950504.1|2167202_2167790_-|CGNR-zinc-finger-domain-containing-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	3.15972e-13
NC_020990.1|WP_003950511.1|2156708_2158013_-|extracellular-solute-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.74301e-91
NC_020990.1|WP_003950518.1|2147840_2150138_-|molybdopterin-dependent-oxidoreductase	gnl|CDD|132240	TIGR03196, pucD, xanthine dehydrogenase D subunit. This gene has been characterized in B. subtilis as the molybdopterin binding-subunit of xanthine dehydrogenase (pucD), acting in conjunction with pucC, the FAD-binding subunit and pucE, the FeS-binding subunit. The more common XDH complex (GenProp0640) includes the xdhB gene which is related to pucD. It appears that most of the relatives of pucD outside of this narrow clade are involved in other processes as they are found in unrelated genomic contexts, contain the more common XDH complex and/or do not appear to process purines to allantoin.	4.68013e-166

Protein sequences

>NC_020990.1|WP_003950511.1|2156708_2158013_-|extracellular-solute-binding-protein
MKLLPRLAAPVAALVLAGLTATACAPQTSDTSSGKDEKTGDLRVWLFQEVNNGPKAKVVDRAVAAYEKAHQGSKVDVQYIPVDSRAEKIKAAFNDPSSAPDVIEYGNTDTAGYVRDGGLADISEEFAAWDEAADTDEAARASVTVDGKTYGAPYFVGVRALYYRTDLFEKHSVAVPETLDEVAAAAKKIRKAEPGLYGIAVGGAYTYGAMPFLWAHGGGLAEEKDGVYTSTLADKKSQAGIAAYTDLFGPDNCPAAKCAQMGGNDTVTAFAAGKAGMAIGGDFSHQAMEDGKVKGKYAVVPLPGTEKGEIAPAFAGGNNLGVLKSTERRSLAVDLVKELAGKKAQSELFDAMGFLPTFTDTRAEAAAEEPFVKPFVQTLDAGATFVPASPAWARIDSSLVLPTMFQEIVSGRKDVAAASRDAAKKMDDAFASAG
>NC_020990.1|WP_003950512.1|2155720_2156677_-|sugar-ABC-transporter-permease
MTQTLTAPATPPVRKGGGGARPPRSGSRRPGWTPWLYLAPALVVLAGLLVYPVYQLGLISVLEYTQAQVSGGEPTSFQGLGNYRQLFTDPQFWQVLTATVVFAALCVLSTLFVGCAFAVLLTRIRALPRLALLIASLGAWATPAITGSTVWMFLFDADFGPVNRLLGLGDFSWTYGRYSAFALVLLEVVWCSFPFVMVTVYAGIRAVPTEVLEAASLDGASQWRVWRSVLAPMLRPILLVVTIQSVIWDFKIFTQIYVMTDGGGIAGQNLVLNVYAYQQAFASSEYSLGAAIGVVMLLILLAVTLVYLRLMRRQGEEL
>NC_020990.1|WP_003950513.1|2154890_2155724_-|carbohydrate-ABC-transporter-permease
MKLVHRPWRLAAEAFALLAAVVVAFPLYWMVLSAFKPAGEIQSDTPRPWTLAPSLDSFRRVFQQAEFGRYFLNSLFVAGSVVVLSALIAFLAATAVTRFKFRFRTTLLIMFLVAQMVPVEALTIPLFFQMRDFGLLNTLGALILPHLAFSLPFAIWMLRGFVKAVPEALEEAALIDGASRTRFLWQILFPLVFPGLVATSVFSFISTWNDFLFAKSFIISDTSQSTLPMALLLFFKPEENDWGGIMAASTVMTVPVLVFFVLVQRRLVSGLGGAVKD
>NC_020990.1|WP_003950514.1|2153251_2154889_-|beta-N-acetylhexosaminidase
MHHLIPAPRHHRPESGPETRLTLGPDTALRTGAGTGTAARWLRTTVGAATGLALPEAAAENPGPVVDLRITGEAGGLGAEAYRLTVSAEGVLIEGGDAAGVFWGAQTLRQLLGPDAFRRAPLNPGRAWQLGHVRIEDAPRFAWRGMMLDVARHFMPKDGVLRHLDLLAAHKLNVFHFHLTDDQGWRVDIRRHPELVRTGSWRPRSKWGHRASELWNDTPHGGYYTHDDIREIVAYAAERHITVVPEIEIPGHSQAAIAAYPELGNTDVTDTASLGVWDTWGINPHALAPTEDTLRFYEGVFEEVLELFPSRFIHVGGDECEKDEWRRSPAAQARIAELGVGDEDGLQSWFIRHFDRWLGARGRRLVGWDEILEGGLAEGATVSSWRGYAGGIAAARAGHDVIMCPEQQVYLNYREDGGPDEPVPIGYVRTLEDVYRFEPVPPELTGAEAAHVIGVQANVWTEVLENQDRVDYQLYPRLAALAEVAWSPLPASAERDFAGFDARMETHFRRLDALGVAYRPPSGPHPWQRRPGVLGRPFEGAPQPG
>NC_020990.1|WP_003950515.1|2152035_2152932_-|dehydrogenase
MTTHAPQAAASVTLPASLDEAVAALAATPAAVPVAGGTDLMASVNAGQLRPTALVGLGRVREIRGWQYLDGHALLGAGLTHARMGRPDFAALIPALAAAARAAGPPQIRNAGTLGGNIATAAPSGDTLPVLAALEATLVVASPGGGRREVSVSHLLAGMDMLRGGELIGWVRVPLLHAPQVFLKATGRTGPGRATASVALVVDPARREVRCAIGAIAPMPLRPLEAERWAASLIDWDGERGLPQEALTAFGTYVATACVPDPEVPADGGEPPKLPPAVLHLRRTVAALARRALGRALS
>NC_020990.1|WP_015507188.1|2150134_2152039_-|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MTDDERGEGTGAARGTSLSWGAIPHQGGEEYDDGATAFVQLPEGIADIPLAAPGQGYVPPITVTPATGPADPAATGVWSIPGAVAGGAPAPDPYAQQPGHGPDPYGTLPPQDVSEAAPGQVVADVYPDGAQVPGADGYPQPPADAFAATDAFGDTRPLTIPPGLSPDGPRPDLGAAFGGAERAGQPHGRPGIPGQQQGPGSAGQDATGHWDFTAALGESAPPAQGGTGQWAVPLAPEDVPEESGEYPLSEAAPRTGAWATAPTHQAPATLPGGATAPWAGEAEATAPEPAPEAAPEATAEEAHEAAHDASDGPEAEEQAESAPEADSAPETADAPAPEPEAEAETEAEAEGAGEEPGGAVEAAGEEAPEAGGLHDERPVVSYTLNVNGIDRPVTEAWIGESLLHVLRERLGLAGAKDGCSQGECGACAVRVDGRVVASCLVPAATTEGSDIHTVEGLGAAEDGGPGEPSDVQRALARHCAVQCGFCIPGMAMTIHDLLEGNPRPTDLETRQALSGNLCRCSGYRAILESVRDVVGEREASAEAAADVAAHDDASAEAEDGEPAGADQAEVAIPHQAGPADGEAPGHPYGALPDGYDGLPQPPPSYDTGGYPPHHGQDGYGYDEQGPHEQHGGQA
>NC_020990.1|WP_003950518.1|2147840_2150138_-|molybdopterin-dependent-oxidoreductase
MSHDTATGIPAQADAEAAPHGLGVSLPLAEARAKTEGTFPYAADLWAEGLLWAAVLRSPHAHARVVSIDTRQAAGMPGVHAIVTHEDVPGEGLHGRYGADRPVFASEVVRHHGEPLAAVAADHPDTARMAAAAIMVEYEVLPAQTDPEEAFTAEPLHPDGNVVRHIPLRHGDQEATGETVVEGVYRIGRQDPAPVGAEAGLAVPRPDGGVELYAASTDPHADRDRAAAVYGLDPERVKVVVTGVPGATADREDPGFLLPLGLLAMRTGCPVKLAATREESFLGHAHRHPTLLRYRHHADAEGRLVRVEAQILMDCGAYTDSSRESLAAAVAFACGPYVVPHATIDGWAVRTNNPPAGHVRGEGALQVCAAYEAQMDKLAKKLGLEPAEVRARNVLATGDVLPTGQTVTCPAPVAELLQAVQDFPLPALPKDTPEEEWLLPGGPEGAGEPGAVRRGVGYGLGMVHMLGAEGADEVSTATVRVQDGRATVICAAVETGQGFTTLARQIVQETLGIDEVTVAPVDTDQPPAGPSCHSRHTWVSAGAVERAAKMVRTQLLQPLAHQFGMSTELLQITDGKITSYDGVLSTTVTEAMDGKELWATAQCRPHPTEPLDGAGQGDAFVGLVFCAVRAVVDVDVEIGSVRVVELAVAQDVGRVLNPAQIAARIEAGLTQGLGAALTENLRAPQGVLRHPDLTGYALPTALDAPDIRIVRLVEERDVVAPFGAKAASAVPVVTAPAAVASAVRAASGRPVNRLPIRPQAAVAQS
>NC_020990.1|WP_003950519.1|2145593_2147375_-|DEAD/DEAH-box-helicase
MTTSASHHLSPAFPGRAPWGTAGKLRAWQQAAMDKYVQEQPRDFLAVATPGAGKTTFALTLASWMLHHHVVQQVTVVAPTEHLKKQWAEAAARIGIKLDPEYSAGPLSKEYQGVAVTYAGVGVRPMLHRNRVEQRKTLVILDEIHHAGDSKSWGEACLEAFEPATRRLALTGTPFRSDTNPIPFVTYEEGNDGIRRSAADYTYGYGSALGDGVVRPVIFLSYSGQMRWRTKAGDEIAARLGEPMTKDAVSQAWRTALDPRGDWMPNVLRAADQRLTEVRKAIPDAGALVIATDQDQARAYAKLIRDITGNKATLVLSDDSGASQRIDDFSKSDDRWMVAVRMVSEGVDVPRLAVGVYATTISTPLFFAQAVGRFVRSRRRGETASVFLPTVPMLLGFANEMEVERDHVLDKPKKDGEEDPYAESEKEMDEANKEQDEDTGEQEQFSFEALESEAVFDRVLFDGAEFGMQAHPGSEEEQDYLGIPGLLEPDQVQLLLQKRQARQIAHSRKKPDSEADLLELPAERRPVVSHKELLELRKQLNTLVGAYVHQTGKPHGVIHNELRRACGGPPSAEATAGQIRQRIDKVREWATRG
>NC_020990.1|WP_003950520.1|2144161_2145475_+|MFS-transporter
MTITSTPGRTEPKKPSEPEEPEAHGDRRPVPPSDPSRRNGAVLVGFTAVTNLADGVMRLALPLLAVRLTDSPALVTTASLALTLPWLLTALHIGVVVDRFDRRMLLWLAGAARVAAMGGLFAAAVTGHLTLGRLLAAGAVLGVADVLAATAGSALVPAAVAREHRPRVNAWMVGAETVGQEFAGPFVGGLLLAAGTGLALGAIGVTYAAAALLLVLLAGRFRPAAPAPGTPAVPVNTRIAEGLRLLWRDPVLRTLSLTAAALNAVWGAWLALMPLHAHQAMGLGPGEYGFLLSGLGIGGLVGAATVTWVNRLLGPRRAMLADLLGTCAMTALPALTTSLWAVAAGAFLGGMGGTLWAVNSRTLTQHKVPDALLGRYTAASRLLCYGALPIGTAAAGLLAELLGTRTVFAVISALALTTVIPFLRRVKAADLTGTSAP
>NC_020990.1|WP_015507187.1|2143438_2143981_-|CGNR-zinc-finger-domain-containing-protein
MLATPALAALVEAFANTLDVDEVTDALATPEELAAWLREYEELDAPDAISPEAHRDYLALRAGLREEMGARVGDVPDPALLAAADEALAAHPVAVSVTGALRPAPGTPADRLPLTRLAIAWSSLVATGDAARLKRCAEHTCAWVFWDVSKNRSRRWCSMQVCGNRNKSRTYAARRRGEGG
>NC_020990.1|WP_003950510.1|2159151_2159445_-|DUF3039-domain-containing-protein
MSTLEPERGAGTGTLVEPTPQTSSGDGDHERYAHYVQKDKIMASALDGTPVVALCGKVWVPGRDPKKYPVCPMCKEIYESMGPGGDKGKGGGDKDKK
>NC_020990.1|WP_015507189.1|2159507_2160080_-|YqgE/AlgH-family-protein
MTEVSSLTGRLLVATPALADPHFDRAVVLLLDHDAEGSLGVVLNRPTPVGVGDILEGWGELAGDPGVVFQGGPVSLDSALGVAVIPGGPGCADPPLGWRPVHGAIGLVDLEAPPELLAAALGSLRIFAGYAGWGPGQLEEELVQGAWYVVESEPGDISAPRPEGLWRAVLRRQRSELAMIATYPDDPSLN
>NC_020990.1|WP_003950508.1|2160430_2161771_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MTVNDDVLLVHGGTPLEGEIRVRGAKNLVPKAMVAALLGSAPSRLGNVPDIRDVRVVRGLLQLHGVTVRPGDEPGELVMDPSHVESANVADIDAHAGSSRIPILFCGPLLHRLGHAFIPGLGGCDIGGRPIDFHFEVLRQFGAKIEKRADGQYLEAPQRLRGTKIELPYPSVGATEQVLLTAVLAEGVTELSNAAVEPEIEDLICVLQKMGAIIAMDTDRTIRVTGVDKLGGYRHQALPDRLEAASWASAALATEGNIYVRGAQQRSMMTFLNTYRKVGGAFEIDDEGIRFWHPGGQLNAIALETDVHPGFQTDWQQPLVVALTQATGLSIIHETVYESRLGFTSALNQMGAHIQLYRECLGGSDCRFGQRNFLHSAVVSGPTRLQGADLVIPDLRGGFSYLIAALAAQGTSRVHGIDLINRGYENFLDKLVELGGKVELPGKALG
>NC_020990.1|WP_003950507.1|2162072_2162354_-|DNA-binding-protein-HU-1
MNRSELVAALADRAEVTRKDADAVLAAFAEVVGDIVSKGDEKVTIPGFLTFERTHRAARTARNPQTGEPIQIPAGYSVKVSAGSKLKEAAKGK
>NC_020990.1|WP_003950506.1|2162760_2164191_-|NAD-dependent-malic-enzyme
MATAPSVSYSMTVRLEVPASGTAVSQLTTAVESHGGSVTGLDVTASGHEALRIDVTIAASSTAHADEIVEGLRGIDGVVLGKVSDRTFLMHLGGKIEMASKHPIRNRDDLSMVYTPGVARVCMAIAENPEDARRLTIKRNSVAVVTDGSAVLGLGNIGPKAALPVMEGKAALFKRFAGIDAWPICLDTQDSDAIVEIVKAIAPGFAGINLEDISAPRCFEIEARLREALDIPVFHDDQHGTAIVVLAALTNALRVVGKSIGDVRVVMSGAGAAGTAILKLLLAAGVKHAVVADIHGVVHAGRDDLVGAEADSPLRWIADNTNPEGVTGTLKEAVVGADVFIGVSAPNVLDGADVAAMAEGAIVFALANPDPEVDPAVARETAAVVATGRSDFPNQINNVLVFPGVFRGLLDAQSHTVNTEMMLAAAGALADVVAEDEVNANYIIPSVFNDKVAGAVADAVSSAAKAVGAAPAPSAV
>NC_020990.1|WP_003950505.1|2164690_2167078_-|UvrD-helicase-domain-containing-protein
MADVRDREISIEQDHLDQVYRRLEEKIHEAEFLMQDAARRGQVGTPGALAERDAQVFRAGIHLNRLNNEFEDFLFGRIDLLLGKDGEKGPDGAYTSVEPADDAVRPDGTADIAETLHIGRIGVLDADYAPLVIDWRAPAAAPFYRSTPVEPGRVVRRRVIRSKGRQVLGVEDDLMRPELTARLDGEPLAVVGDGALMAALGQARSHTMRDIVASIQAEQDRVIRAPAASVTLVEGGPGTGKTAVALHRAAYLLYQDRRRYAGGILIVSPTPLLVSYTEGVLPSLGEEGQVAIRALGSLVDGAEATAYDTPAAARAKGSARMVQVLRRAARGALDLGTARPAPAGEDEEREEVPEGQLDLGLPAPAGPPERLRVVAFGRRIELDAAELGRIRRNALSGTAPVNLLRPRARRLLLDALWARSGASGRHQDPELAAELRSGFDEDILSEDSFTAFLDAWWPELTPRAVLAAMADEKRLARWSRKVLNQGEVRRVARSLARLGPMGEGPLSVHDVALLDELEAVLGAPPRPRRKREADPLDHLTGLQELMPVREETQWERAERLAQERTEYTHVIVDEAQDLTPMQWRMVGRRGRQATWTVVGDPAQSSWSDPDEAAEARDEALGRRPRRRFTLTVNYRNPAEIAELASRVLALAMPGSDSPRAVRSTGVEPRFVVAGERMGETVRAEAARLLETVDGTIGVVVPMERREQAARWVAGLGERVVALGSLEAKGLEYDATVVVSPAEVADESPAGLRVLYVALTRATQELTVVSGRRDQPDADGVPDLLRDDVPAELLGE
>NC_020990.1|WP_003950504.1|2167202_2167790_-|CGNR-zinc-finger-domain-containing-protein
MTGHAYRAGASARVLRFDCGRVCLDLAATAHPVERLDGPDRLRQWLAGAGLVPPGTPLERAGPGWLAAFRDLRTQIAAVVGAELDGRPPGHALDRVNAVARNPPPPPRAVRRADGTLGRGLSGDPDCQALLGAVARDAVDLLTDPGARALLRRCAGQDCPLVYLDTSRGRRRRWCSGETCGNRERVARHRRSRRG
>NC_020990.1|WP_015507191.1|2167971_2168580_+|GNAT-family-N-acetyltransferase
MSMPAFLPAGPGLSLRPWRARDARELIDAYRDPLLRQFTRTWPEDEAGARAWLAREEAGARDGSRYSFAVELAAQAPDGTGPAPSGVRDPAATGLLAGCVVLKVFPHDDDRPARTDTAEVGYWTTASVRGRGLAGRAVLALADWAFTALPALTRLELLHQVDNEPSCRVAEKAGFPHHETLAPQPPVFPLPGHVHVRPRPAA
>NC_020990.1|WP_015507192.1|2168580_2169696_-|uroporphyrinogen-III-synthase
MGEASPLVGFTVGVTAERRAQELGALLGRRGAEVVYAPALRVVPLADDRELREATEELVARPPEIVVASTAVGFRGWVEAAEGWGVGGALREALGGARLLARGPKVTGAVRAAGLREEWSPRSEAMEEVRERLLADGVAGLRVAVQLHGEPVPGFAEALRAAGAEVVGVPVYRWLPPADLTPVDRLVDATVRRTLDALTFTSAPAVVSVLRRAEALGLREALVDAVNGDVAVVCVGPVTARPLQEAGVEPVQPERYRLGPMVQRLCEELPARTPELAVAGHRVQLRGHAVLVDGEARPVPPAPMALLRALARRPGRVVARAELLRALPGAGRDEHAVESATARLRTALGAPELVRTVVKRGYRLAVDDPEG
>NC_020990.1|WP_003950501.1|2169871_2170933_-|hypothetical-protein
MNAVRRGTWSLLAVALLIPLLTHPARADELPDTSTGGSGGGDSQEVGAQVQNSTIKISQIKGGGGGEKGNLAPIDVDWEPPACWYEPVYTPEQLKKAVEDDSISAVGLHEFWPQSSFQEHYDEGKPRDNFDLYEDEASTAEGYKNYNVGKGGYFWRGVAPDDSHPDSWNCGRLMFWMPDNQVPQIPNAPTPQMLAEYAYEHVKVPDTEVEVRPQARSTVNLPTWVWLDKGKFEDVVVRAELPRTNLYAETTAHPVSLTLEPGTEDAETFPADGTCRINDDGSIGSPYKKGSADQDPPCGITYLRASDEPYQLSASITWEISWEGTGGTGGDLPDGTFETTQDMTVQEIQSINR

Crispr_ID: NC_020990_10

• CRISPR_ID: NC_020990_10
• CRISPR_location: 2343595-2343679
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_10

Consensus_repeat	Method
AGCCCGGCCGGCGTTTGAGGCCA	CRISPRCasFinder

spacers of NC_020990_10

>10.1|2343618|39|NC_020990|CRISPRCasFinder
TCGGTGACGGACGGCTGAGGCATCACCTCAGCCAATCCC

CRISPR arrays and Neighbor proteins around NC_020990_10

CRISPR arrays

The CRISPR arrays of NC_020990_10

>merge|NC_020990|10|2343595-2343679|CRISPRCasFinder
AGCCCGGCCGGCGTTTGAGGCCATCGGTGACGGACGGCTGAGGCATCACCTCAGCCAATCCCAGCCCGGCCGGCGCTTGAGGCCA

>NC_020990|10|8|2343595-2343679|CRISPRCasFinder
AGCCCGGCCGGCGTTTGAGGCCA	TCGGTGACGGACGGCTGAGGCATCACCTCAGCCAATCCC
AGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003950359.1|2351679_2352453_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NC_020990.1|WP_015507241.1|2348247_2349042_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|378925
NC_020990.1|WP_003950376.1|2334432_2335449_+|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NC_020990.1|WP_037629923.1|2349143_2350127_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_020990.1|WP_003950358.1|2352524_2355050_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223650
NC_020990.1|WP_003950363.1|2347971_2348238_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224393
NC_020990.1|WP_008417688.1|2338069_2338609_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_008417684.1|2337086_2337596_+|hypothetical-protein	unknown	unknown	gnl|CDD|224929
NC_020990.1|WP_003950369.1|2340859_2342257_-|cystathionine-beta-synthase	unknown	unknown	gnl|CDD|273464
NC_020990.1|WP_003950372.1|2337652_2338027_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507239.1|2339773_2340217_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950364.1|2346695_2347646_-|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl|CDD|378959
NC_020990.1|WP_003950368.1|2342406_2343456_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238874
NC_020990.1|WP_003950374.1|2336238_2337048_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950366.1|2345414_2346215_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950360.1|2350308_2350914_+|GrpB-family-protein	unknown	unknown	gnl|CDD|377252
NC_020990.1|WP_015507238.1|2338785_2339619_-|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224651
NC_020990.1|WP_003950365.1|2346291_2346603_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950375.1|2335831_2336242_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950367.1|2343866_2345087_+|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|181146

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003950359.1|2351679_2352453_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	6.54367e-107
NC_020990.1|WP_003950376.1|2334432_2335449_+|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.62971e-115
NC_020990.1|WP_037629923.1|2349143_2350127_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.12222e-86
NC_020990.1|WP_003950358.1|2352524_2355050_+|ABC-transporter-permease	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	2.56715e-25
NC_020990.1|WP_003950363.1|2347971_2348238_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	1.27369e-18
NC_020990.1|WP_008417684.1|2337086_2337596_+|hypothetical-protein	gnl|CDD|224929	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only].	1.31302e-19
NC_020990.1|WP_003950369.1|2340859_2342257_-|cystathionine-beta-synthase	gnl|CDD|273464	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase. Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. The function of any bacterial member included in this family is proposed but not proven. [Amino acid biosynthesis, Serine family].	0
NC_020990.1|WP_003950364.1|2346695_2347646_-|Bax-inhibitor-1/YccA-family-protein	gnl|CDD|378959	pfam12811, BaxI_1, Bax inhibitor 1 like. The Bax-inhibitor-1 region of the receptor molecules is conserved from bacteria to humans.	2.93652e-85
NC_020990.1|WP_003950368.1|2342406_2343456_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238874	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases. FeeA and FeeB are part of a biosynthetic gene cluster and may participate in the biosynthesis of long-chain N-acyltyrosines by providing saturated and unsaturated fatty acids, which it turn are loaded onto the acyl carrier protein FeeL. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	4.07513e-49
NC_020990.1|WP_003950360.1|2350308_2350914_+|GrpB-family-protein	gnl|CDD|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	7.93459e-63
NC_020990.1|WP_015507238.1|2338785_2339619_-|MurR/RpiR-family-transcriptional-regulator	gnl|CDD|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	2.4621e-36
NC_020990.1|WP_015507241.1|2348247_2349042_-|ABC-transporter-permease	gnl|CDD|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	1.38196e-15
NC_020990.1|WP_003950367.1|2343866_2345087_+|acetyl-CoA-C-acetyltransferase	gnl|CDD|181146	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase.	0

Protein sequences

>NC_020990.1|WP_003950368.1|2342406_2343456_+|SGNH/GDSL-hydrolase-family-protein
MARRIAAGAAYGGGGIGLLGVAGVGVLLAEAQLAKRSVGSQGNGAAPPRADGVYGRAFGIRPDGEPPLEPLRFLMLGDSTAAGQGVHRSRQTPAALLASGLAAVAERPVELRNVAVPGARSDDLDRQVSLALADGGWVPDVCVLMVGANDVTHRMAATESVRLLASAVRRLRTAGAEVVVGTCPDLGTIEPVYQPLRWLARRASRQLAAAQTIGTVEQGGRTVSLGDLLGPEFAQNPRELFGPDNYHPSAEGYATAAMAVLPTLCASLGLWPEGERPEAARDEGFLPVARAAVRAASEGGTEVTAATGPRGPLALLKRRRRRRIPHEPSPTPAPQTPAPDRGGLNRRPG
>NC_020990.1|WP_003950369.1|2340859_2342257_-|cystathionine-beta-synthase
MHIHDSMVDLVGNTPLVRLNNVTEGIQATVLAKVEYFNPGGSVKDRIALRMIEDAEERGLLGPGSTIVEPTSGNTGVGLAIVAQQKGYKCIFVCPDKVSLDKINVLRAYGAEVVVCPTAVDPEHPDSYYNVSDRLVRETPGAWKPDQYSNPNNPLSHYHSTGPELWEQTDGKITHFVAGIGTGGTISGTGRYLKEVSDGAVQVVGADPEGSVYSGGSGRPYLVEGVGEDFWPTAYDRNITDRIVAVSDKDSFQMTRRLAKEEGLLVGGSCGMAVVAALEVAREAGPDDVIVVLLPDSGRGYLSKIFSDEWMNDYGFLDQGGDEPRVGDVLRDKEGAMPSLVHMHPEETVGEAIEVLREYGVSQMPIVKPGAGHPDVMAAEVVGSVVERELLDALFASRAALDDPLEKHMSRPLPQVGSGEPVADLMAVLGKADAAIVLVEGKPTGVVSRQDLLSFLARSAGTAVE
>NC_020990.1|WP_015507239.1|2339773_2340217_-|hypothetical-protein
MKMRKVGRAFFVLSVAAGMTVALQGSASAASYTYRATDVSGGPDWNQLKACSYVNYNGEAGRACFQPNGDKFWVQDLKADGHHVEMNAQVNVNGNWYHCLNYHGKAAGWTSCSFATVVPENARIAYNVSVWEGDKLLRSGQLIAADT
>NC_020990.1|WP_015507238.1|2338785_2339619_-|MurR/RpiR-family-transcriptional-regulator
MTHSPAGRLQGLFEGRRLTPTQRRIAHCMVRHADEVPFLSSVELAELAGVSQPSVTRFAVALGFDGYPALRRDLRERAPGAPSAPAEANGYQQAVEAEVANLRRLADFLADPAPLQRAGRLLAQSRPLPVLGLRAAAAQARGFAYFAAKVHPDVRLLDEGGTMLVDRIDAARLAGASALLCFALPRHPREVVEALAYARERGLTVVTVADSAFAPVAAESDILVPGAVGTGLAFDTACAPMLLGRVLLEAMCDALPDAQARMERFDVRAADRGLFAD
>NC_020990.1|WP_008417688.1|2338069_2338609_-|hypothetical-protein
MAVVQRAGAAPLWWLGVVAAGAGLVPEGLTGRRIGVLVGALLFLLAAAVVPLVRGGRAAALAAEAERAARSDILQARSVTVRNWRRGHRWWLLLAFAAALGSAFALPAAGGMALAGWGAGLWLRARGTGRVEEAREVLLWTAADALGRGAGDPLGARTTRLWTTGTEAGDAAPGGGRRR
>NC_020990.1|WP_003950372.1|2337652_2338027_+|hypothetical-protein
MANTETSLKEAMSIIEGATGVALVDYTSGMALGTLGGGKDFNLEVAAAGNTDVVRAKLRTMEHLGLKEEIEDILITLSGQYHLIRLLKSRGGNGLFLYLVLDAGRANLAMARHQLRRIETELEV
>NC_020990.1|WP_008417684.1|2337086_2337596_+|hypothetical-protein
MAAEREVLDELQRLRARVPLLSGALAASADGLVLAQDTAGVEAESLAALTAAALGVAVRLTDATARGSFRELLVRGEKGYVATYAAGSSAVLTLLAEDRINVGRLHLEGRRAGTRIGALVDAALERAATPQPRPEHTRTAMPARPAAPPPQAPGPATGTPPGVLPRRPV
>NC_020990.1|WP_003950374.1|2336238_2337048_+|hypothetical-protein
MRPPASPAPTAPLPAVSPMLRRLAEERATGALMRESGTLYLADGQVVHAESPATPGIDVLLTAGGTLARAGWWEAVAAAGARQRVAAYLVDSGRVPGGALELCHLGALYDAAFFALAPTSTPARFRYGVSHWIGPVHPVAAGSVERETLRRRALLDRIWPDATVDTAPLVRLPDAAAPPLTPRRRAVLAAVDGSRSAAEIARGLGRSAFHTLVDVRRLAAAGALDAVRSCGRPDDGSSGPRAGAPVLPEVTPDPDIALLRRLRDALEVL
>NC_020990.1|WP_003950375.1|2335831_2336242_+|hypothetical-protein
MPGIDECLLDIMKLPGARGAAVVDWTSGLALGTIGESPHDDHEATAAETAEVARMAAEQPAFAQESARAGTPPEDPPASGVEDVIVTSPAGYHILRFVETDFDSSVFVHLWLHRSEGNLALARIRLGELARRLVLA
>NC_020990.1|WP_003950376.1|2334432_2335449_+|LacI-family-transcriptional-regulator
MGSRQRPTIKTVAARAGVGRTTVSRVINGSELVSDEARTAVLAAIAELNYVPNSVARGLVTSRTDSVALVIPESESRLGSEPYFSAVIRGVSTGLTERRIQLQLVLVRDQAERDQLTESVAERRVDGVLLVSVHEQDPLPGLLENMGLPTVLAGRRAHGEPLSHVRADNEGGAAAAVAHLVARGRRRIATISGPLDMDVSRSRLDGWRDALRDEGVEAAETLVATADFTEAGGEAAMRSLLERDPGLDAVFAASDVMAAGALAELRRQGRRVPDDVALIGFDDSVIARHSNPPLTSVRQPVEAIGRRMAQILLAEIDDPGQPRQHVVLPTELVVRESS
>NC_020990.1|WP_003950367.1|2343866_2345087_+|acetyl-CoA-C-acetyltransferase
MPEAVIVSAARSPIGRAFKGSLKDVRPDDLTAHIIETALAKVPELNPRDIDDLMLGCGLPGGEQGNNLGRIIAVQMGMDHLPGCTVTRYCSSSLQTSRMALHAIKAGEGDVFISAGVETVSRFAKGNSDSLPDTRNPVFAEAEARTAAVAEQGADSWHDPREDGKLPDAYIAMGQTAENLARLKGVTREEMDEFGVRSQNLAEEAIKKGFWEREITPVTTPDGTVVSQDDGPRAGVTLEGVSGLKPVFRPDGRVTAGNCCPLNDGAAALVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGYGPVEASNQALRRAGLTIDDIDLAEINEAFAAQVIPSYRDLGLPLEKVNVNGGAIAVGHPFGMTGARITTTLINSLQFHDKQFGLETMCVGGGQGMAMVIERLS
>NC_020990.1|WP_003950366.1|2345414_2346215_+|hypothetical-protein
MTLALLIALAAVVAVGAVALHAVHGLRRQIAALRAELHATHSGRATVPAARADADGIREAVAEALAEERERELAEARAFWAAQEARDASDAPSLLGGLHGLVDDLFIPRQADLAGLDALDAAEAAQHLPAAEPEEDSPELAAARRRHPSHPDFVPVRPTPVERETAGDDHETTVAVLEELAQARTALADVRPGPLGTLDVYVFADGTTLCMTPGHRETAELLAGSLRAGEAPVLLGGSGVSGAYALTFSCGEDNVYLLADRVIASV
>NC_020990.1|WP_003950365.1|2346291_2346603_-|hypothetical-protein
MLDTTPLTSAVDQFADRLRAAPQSRLQRGAAAEALELARELSARAQRLEEPSGEVRVMPDAGMFAVADQVTVAAHDLALVLPGEAALESAVARVAEARERAGI
>NC_020990.1|WP_003950364.1|2346695_2347646_-|Bax-inhibitor-1/YccA-family-protein
MRSSNPVFSRRGFSRDNGHAQFNAAPQAGGPAVGTQQGNPYAGGNPYAGQNPYAGQNPYAGQNPYAQGDQQTYANPYAQDQYGVQAPTTDRMTMDDVVMRTATTLGTLIVTAALAWWFLPVDAANMGKSYGIAIGAGLVAMVLALVQSFKRKASPALILAYAALEGVFLGVVSNVVDTHIASGAAMQAVIGTMAVFTAVLVAYKAGWIRVNRRFYGFVMAAAMGFVLLMAVNLLFAVFGGGDGLGFRSGGLGIIFGIIGVLLGACFLALDFKQVEDGIAYGAPREESWLAAFGLTMTLVWIYMEFLRLIAILQGDD
>NC_020990.1|WP_003950363.1|2347971_2348238_-|helix-turn-helix-transcriptional-regulator
MTPRTEGAGSGAAAAPDPVHNRIAMLRVERQVTRRQLADALGVHYQTIGYLERGEYSPSLHLALRIAAYFEVPVEFIFSLTPFAPLKP
>NC_020990.1|WP_015507241.1|2348247_2349042_-|ABC-transporter-permease
MNSLRTPTDVGYYVIGSAVFLFVILRNRDNIDETTGLSAGALMLPGVLAFSMIFAALFGLATAVATEREDGTLLRAKSLPHGTTGYVVGQSTRTALEVCFSLTLLLVPGLILLDDGWSGGVWGVPHAASLLVLGVLASTPLGFAVGSLVKNPRTLGGWGFLLMGGMVAISGTFFPLSVMPGWAAWLGQVFPLYWLGHGLRSAMLPDAAAAGEINGTWQVWESYAVLGAWALLGLVLAPVLLRRMARRESGASMSARKETALQRY
>NC_020990.1|WP_037629923.1|2349143_2350127_-|ABC-transporter-ATP-binding-protein
MGEPEMAFDSGGTGGGGEVVVDVRDLWMRYGEKDVLRGVSFEIRRGEVLGLLGPNGAGKTTTIEIMEGFRQPSSGHVRVLGEDPLHGGDAWRARVGVVLQSWRDHSRWRVGALLEQFASYYRPYAGRDGCPGPYEVAELLARVGLSDKAETRVGALSGGQRRRLDVAVGIVGRPRLLFLDEPTTGFDPKARSDFHDLVHALADLEDTTVLLTTHDLAEAEKLADRILILDGGRIVADGSAEQLARQVAGEDEVRWTRDGVREVHLTPDGTRFTRELFERYGAEITELEVRRASLEDTYLRMVARSEAGLEEPAPDQETVRERTGEPA
>NC_020990.1|WP_003950360.1|2350308_2350914_+|GrpB-family-protein
MPDQQPPDRPEDRTPMTDTEIEAAYVTAPPRLNGPVTLAPYDPRWPEAYAALAARIGERLTPLPHRLDHAGSTSVPGLPAKPVLDLVLTVPDPADEDAYVPALAPLGLRLTIREPDWYAHRLLRGAAGHPAADAVNLHVFPEDCPETARMLRFRDHLRADAADRDLYARTKRELSARSWTYTQQYADAKSEVVAEILRRAG
>NC_020990.1|WP_003950359.1|2351679_2352453_+|ABC-transporter-ATP-binding-protein
MTTTTPLASRSTEVAARATELSKVYGTGETRVVALDQVSIDFRQGELTAIMGPSGSGKSTLMHCVAGLDTFDGGSVRIGDTELGALKDKQLTQLRRDKIGFIFQAFNLLPTLTALENITLPMDIAGRKPDQAWLDQVIDMVGLRDRLKHRPAQLSGGQQQRVAVARALASQPEIIFGDEPTGNLDSRSGAEVLGFLRNSVRTLHQTVVMVTHDAVAASYADRVVFLADGRIVDEMHRPTADSVLDRMKEFDAKGRTS
>NC_020990.1|WP_003950358.1|2352524_2355050_+|ABC-transporter-permease
MFRTALRNVLAHKARLLMTVLAVMLGVAFVSGTLVFTDTLGNALRNQSAKSYDDVAVSVQTYADQRDQEKTGIDAATLEKIQGIDGVAAAHGRVSGFAGVADPDGKLIGSGWSNTGANFAPGADGKDPQYVFTDGKGPKAGQVALDRATADQGEYQVGDKVRVATNGPVQELTLSGVFTTEDGAVNAGGSLVLFDQRTAQKQYLRPGYFKDVTVTAASGASDTALLEKVEALLPEDATAQTGQALAEEQAKDIESGLTGLNTMLLAFAGIALFVGVFLIANTFTMLIAQRTRELALMRAVGASRRQVKRSVLAEAALVGLVASAVGFGLGLGLAVALRSAMDAFGAEMPAGPLVVSPVAVGSAFGVGVVITVLAAWLPARRAAKIPPVAAMNSVHAVATVKSLVVRNTIGSIVTAAGAVAIVAGASKGGGEGRYLIAGGAFFALLGVMVLIPLLSRPVIAAVRPLLTKVFGVSGKLAAQNAVRNPRRTGTTASALAIGLTLVTGLSVLGLTVGQAIDRMTTDHIRADYMVTMASGRPMDSSALKALEGADGVSAVSPKQAAGFQFEDDYLGASSVTPGAVDKVFHLKVVDGSLATLEDGAIAVDTKTADKRGWKVGDTLPVTFDDEKKGELKVGATFEGNEFLDSVLIDRAVADAHEAAPMIMEIWVNTAGGPSDSARQALVDALGNNPAIDVMDQQEIRNAFGGMINTMLYIMYGLLAMALIIAVLGVVNTLAMSVFERQQEIGMLRAIGLDRRRVKRMIRLEAVVISLFGAVLGTALGVFLGWAIGETIAESVPGYELVLPWDRIAIFLALAGLVGVLAALWPARSAARLNMLTAIKTE

Crispr_ID: NC_020990_11

• CRISPR_ID: NC_020990_11
• CRISPR_location: 2706279-2706370
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_11

Consensus_repeat	Method
GACTGGCCTCAATCGCCGGCCGGGCTGT	CRISPRCasFinder

spacers of NC_020990_11

>11.1|2706307|36|NC_020990|CRISPRCasFinder
CGGTTGCCGGGCTCCGTCTCGACCGTGCCGGTCAAA

CRISPR arrays and Neighbor proteins around NC_020990_11

CRISPR arrays

The CRISPR arrays of NC_020990_11

>merge|NC_020990|11|2706279-2706370|CRISPRCasFinder
GACTGGCCTCAATCGCCGGCCGGGCTGTCGGTTGCCGGGCTCCGTCTCGACCGTGCCGGTCAAAGACTGGCCTCAAACGCCGGCCGGGCTGT

>NC_020990|11|9|2706279-2706370|CRISPRCasFinder
GACTGGCCTCAATCGCCGGCCGGGCTGT	CGGTTGCCGGGCTCCGTCTCGACCGTGCCGGTCAAA
GACTGGCCTCAAACGCCGGCCGGGCTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003950033.1|2698618_2698882_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950021.1|2716710_2717094_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NC_020990.1|WP_008415563.1|2714362_2714887_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950022.1|2715700_2716594_+|1,4-dihydroxy-6-naphthoate-synthase	unknown	unknown	gnl|CDD|270353
NC_020990.1|WP_003950031.1|2700758_2701025_+|DUF2530-domain-containing-protein	unknown	unknown	gnl|CDD|378488
NC_020990.1|WP_003950037.1|2694648_2695644_+|aldo/keto-reductase	unknown	unknown	gnl|CDD|381313
NC_020990.1|WP_003950032.1|2698955_2700401_-|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NC_020990.1|WP_003950020.1|2717235_2717487_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_010643325.1|2703737_2704598_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950027.1|2707191_2710425_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507347.1|2711582_2712443_-|DUF3027-domain-containing-protein	unknown	unknown	gnl|CDD|378605
NC_020990.1|WP_015507348.1|2712854_2714333_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_020990.1|WP_003950035.1|2696532_2697879_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_020990.1|WP_015507349.1|2714907_2715633_+|futalosine-hydrolase	unknown	unknown	gnl|CDD|236194
NC_020990.1|WP_051085198.1|2717795_2718500_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_020990.1|WP_003950028.1|2704943_2706203_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NC_020990.1|WP_003950034.1|2697982_2698420_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_020990.1|WP_003950036.1|2695863_2696454_-|RNA-2',3'-cyclic-phosphodiesterase	unknown	unknown	gnl|CDD|274058
NC_020990.1|WP_003950018.1|2719084_2721016_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|225183
NC_020990.1|WP_003950030.1|2701193_2703632_+|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl|CDD|319795

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003950022.1|2715700_2716594_+|1,4-dihydroxy-6-naphthoate-synthase	gnl|CDD|270353	cd13635, PBP2_Ttha1568_Mqnd, A menaquinone biosynthetic enzyme exhibits the type 2 periplasmic-binding protein fold. This group includes Ttha1568 (MqnD) from Thermus thermophilies HB8, an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. Ttha1568 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.21409e-142
NC_020990.1|WP_003950031.1|2700758_2701025_+|DUF2530-domain-containing-protein	gnl|CDD|378488	pfam10745, DUF2530, Protein of unknown function (DUF2530). This family of proteins with unknown function appears to be restricted to mycobacteria.	0.00433448
NC_020990.1|WP_003950037.1|2694648_2695644_+|aldo/keto-reductase	gnl|CDD|381313	cd19087, AKR_AKR12A1_B1_C1, AKR12A, AKR12B, AKR12C families of aldo-keto reductase (AKR). Streptomyces fradiae TylCII, Saccharopolyspora erythraea EryBII, and Streptomyces avermitilis aveBVIII are founding members of aldo-keto reductase family 12 member A1 (AKR12A1), B1 (AKR12B1), and C1(AKR12C1), respectively. TylCII acts as a NDP-hexose 2,3-enoyl reductase. EryBII is a mycarose/desosamine reductase involved in L-mycarose and D-desosamine production. aveBVIII functions as a dTDP-4-keto-6-deoxy-L-hexose-2,3-reductase.	2.50541e-167
NC_020990.1|WP_003950032.1|2698955_2700401_-|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.89915e-107
NC_020990.1|WP_003950021.1|2716710_2717094_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	5.07314e-27
NC_020990.1|WP_015507347.1|2711582_2712443_-|DUF3027-domain-containing-protein	gnl|CDD|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.47353e-109
NC_020990.1|WP_015507348.1|2712854_2714333_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.23737e-18
NC_020990.1|WP_003950035.1|2696532_2697879_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.218e-81
NC_020990.1|WP_015507349.1|2714907_2715633_+|futalosine-hydrolase	gnl|CDD|236194	PRK08236, PRK08236, hypothetical protein; Provisional.	6.12362e-66
NC_020990.1|WP_051085198.1|2717795_2718500_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	9.25685e-26
NC_020990.1|WP_003950028.1|2704943_2706203_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	4.41532e-72
NC_020990.1|WP_003950034.1|2697982_2698420_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.04287e-20
NC_020990.1|WP_003950036.1|2695863_2696454_-|RNA-2',3'-cyclic-phosphodiesterase	gnl|CDD|274058	TIGR02258, UPF0097_protein_AF_2157, 2'-5' RNA ligase. This protein family consists of bacterial and archaeal proteins with two tandem copies of Pfam domain pfam02834. Members for which activity has been measured perform a reversible, ATP-independent 2'-5'-ligation of what is presumably a non-phyiological substrate: half-tRNA splice intermediates from an intron-containing yeast tRNA. The physiological substrate(s) in prokaryotes may include small 2'-5'-link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles. [Transcription, RNA processing].	3.86408e-35
NC_020990.1|WP_003950018.1|2719084_2721016_-|ABC-transporter-ATP-binding-protein	gnl|CDD|225183	COG2274, SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms].	1.62769e-36
NC_020990.1|WP_003950030.1|2701193_2703632_+|HAD-IC-family-P-type-ATPase	gnl|CDD|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0

Protein sequences

>NC_020990.1|WP_003950028.1|2704943_2706203_+|cytochrome-P450
MPSSAPPEQEPLVLDPTGADPHAEHRALHARGPATRVDVLGVPAWSVSDPALLRALLTSPDVSKDGRAHWPAFAETVQSWPLALWVAVRNMFTSYGADHRRLRRIIAPAFSARRVEAVRPVVERITAGLLDDLAALPPDAPVDLREKLAYPLPVAVIGHLMGVPEERYAHFRAVVDGVFDTTLGREEAAANTDALYVVLDELIATRRAEPGDDLTPLLLATPDEEGAEPALSHEELRDTLLLVISAGYETTVHVIDQAVHALLTVDGQLDLVRSGQVGWGDVVEETLRHESAVKHLPLRYAVRDIPLPDGRTIARGEAILASYAAANRHPGWHDDADVFDAGRLSKEHLAFGHGVHFCVGAPLARLEVEVCLRLLFARFPGLALDLPAEGLPPFPSLISNGHRNLPVWLHGGALGEGPG
>NC_020990.1|WP_010643325.1|2703737_2704598_-|hypothetical-protein
MRIRATVAVVSGALALSALTGAAAQAAPGPDRERIQVPTAESVFGKQATAKGKGFKAAAVPKISKVTVNGGKDIVLGTTKAKTFSVSITASHASNIGDAYAYFWHGSTYETADGVFIPNEEYASCKASSTTTSTCKLTFTVDPQWELINDLAGSWNVGVGALAADDSDFAWNDKHSKTRVQRYSKLVVNATPEPVKKGKTLTVNGTLSRANWDTWKYAGYTQQSVKLQFKKKGAASYTTVKTVKSGSKGALKTTVKAASDGYWRWSFAGTSTTPAINSTADFVDVK
>NC_020990.1|WP_003950030.1|2701193_2703632_+|HAD-IC-family-P-type-ATPase
MTQRGQVDTGGSDSGNSRIDTGAEPDAAPPAVPPEPGLSSAEVAEAVARGEVNDVPVRSSRSLAEIARANIFTRFNAIIGVLWVIMLFVAPIQDSLFGFVIVANTGIGIFQEWRAKRTLDGLAVIGEAKPTVRRDGRPGEISTSEIVLGDLIEIGPGDKIVVDGEVREADGLEVDESLLTGEADPVVKRPGDEVMSGSFVTAGGGAFRATKVGREAYAAQLAEEASRFTLVHSELRSGISTILKYVTWMMVPTAIGLVVSQLVVRDNDFKNAVARTVGGIVPMVPEGLVLLTSVAFAIGVIRLGRKQCLVQELPAIEGLARVDTVCLDKTGTLTEGGMDVQAIRPLGGADEAYVRRVLGALGAGDPRPNASLQAVIDACPAPEGWRTTGTLPFSSARKYSGASLDEGDATHRTWLLGAPDVLLRPGAEALAETDALNERGLRVLLLSRAAGGLDGPDPGAGAEPTALVVLEQRLRPDAADTLRYFEDQHVAAKVISGDNAVSVGAVAGKLGLPGAERTYDARKLPKEPEALADTLDENTVFGRVTPQQKRDMVGALQAHGHTVAMTGDGVNDVLALKDADIGVSMGSGSEATRAVAQIVLLNNSFSTLPSVVAEGRRVIGNITRVATLFLVKTVYSVLLAILVVLSQTEYPFLPRHLTLLSTLTIGVPAFFLALAPNKERAQPHFVKRVMRYAIPGGVIAALATFTTYMTARAYYTGPDSLPAETSAATLTLFLVSLWVLAIIARPYTWWRVGLVATMAGAFLVVLAVPWLQDFFALRLVGSVMPWAAVGIAVIAAALIEVVWRLVDRRLPV
>NC_020990.1|WP_003950031.1|2700758_2701025_+|DUF2530-domain-containing-protein
MKKWTPRHEAPEPLEGPVVATITGGTILWFVLFLAQLPFYGWYDDRGHTWWIWTCLAGAGLGCLGVWYVRRREAALKRAATAAPQPGS
>NC_020990.1|WP_003950032.1|2698955_2700401_-|NCS2-family-permease
MPTSAPAQDATSEQPNPPSGALDRYFKITERGSTLSREVRGGFATFFAMAYIIVLNPIILGSAKDMYGHQLDNGQLVTATVLTAALTTLLMGVIGNVPVALAAGLGVNTVVALQLAPRMSWPDAMGMVVLAGFVVMLLVATGLRERVMSAVPLGLRKGIAIGIGLFIMLIGLVDAGFVSRIPDAAQTTVPLQLGADGHLNGWTVLVFVLGVLLTLALMVRKVPGAILISIVAMTVLALIINAVADIPSWGLTTPEWPGNPVATPDFGLIGQVSLFGGFAKVGLLTGILFVFTVLLSCFFDAMGTIMAVGDEAELTDAQGNMPGINKVLFVDGIAVAAGGASSSSATTCFVESTAGVGEGARTGFANIVTGGLFAIGLFLTPVVTMVPSQAATPALVAVGFLILSGSIGAIDWTDFTIAIPAFITFMMMPFTYSITNGIGMGFISFCVLRLAAGRGRSVPAAMYVVSGVFAFYYLMPALGLT
>NC_020990.1|WP_003950033.1|2698618_2698882_+|hypothetical-protein
MDTHVLSLRMDSELFERLRGHAARRGMSVQDYVVRTMIRDDFDQRFQTAVEETEKFYGDEDGGAPRAGEVAEEPARDGAVNGAARPT
>NC_020990.1|WP_003950034.1|2697982_2698420_-|MarR-family-transcriptional-regulator
MPDLTHGEDADAVNALRSSVMRLSRRLKHQRVDESLSPTEMSVLGTLARCGTATPGELARKEHVQPPSMTRIVALLEAKGLVRLEPHPEDRRQKVVTQTEEAEAMLEESRSKRNAWLASLAAELDEEEWAKVRAAAPVLEKLAHL
>NC_020990.1|WP_003950035.1|2696532_2697879_-|MFS-transporter
MSTGPGADSAPAPAAHDSTPPAPKQSMFSSLKIHNYRLFFTGQVISNTGTWMQRIAQDWLVLTLTGSSAAVGVTTALQFLPMLLFGLYGGVLVDRLPKRPLLLFTQSAMGLTGLALAALTLTGHVQVWHVYVTAFVLGLVTVVDNPARQTFVSEMVGPRQLANAVSLNSANFQSARLVGPAVAAVLISAVGSGYAFLINGLSFAAPIAGLLMMRMGDLHKAPRTPRGKGQLREGLRYVAGRPDLIWPIVLVGFIGTFGFNFPIWLSAFADKIFDGGPGMYGTLNTLIAAGSLAGALLAARRGAGRLRLLVAAAAAFGVLEIVAAFAPSVWIFAVLMVLTGMFGLTVNVTANSYVQMATEPQMRGRVMALFMMVFTGGTPLGAPLLGWITDEYGARTGFAVGGAISLLAALAVGLILARVGGLKVKVDLRRGRKHIRFVPDEKRLAPAA
>NC_020990.1|WP_003950036.1|2695863_2696454_-|RNA-2',3'-cyclic-phosphodiesterase
MASPAPRPRLFVAVVPPDAVLAELRRATAALDALPGAGRLRPTEAGGRHVTLAFLGACDPGHLDGLAARLARAAHRTAPFPLALRGAGHFGDRVLWARPDGDLDALARLADRVRAAATRAGLPPDAEHAFRPHLTLARVRPGPPLRLAPFAEALAQLAAGPWQADEVRLLRSVPPPGGVPGARPTYATEGRWPLGG
>NC_020990.1|WP_003950037.1|2694648_2695644_+|aldo/keto-reductase
MKYTQLGRTGLKVSRLVLGTMNFGPKTGEAESHALMDTALDDGINFFDTANVYGWGENKGRTEEILGTWFAQGGDRRDKVVLATKVYGNMGADGSAWPNHDRLSALNIRRAVDASLRRLQTDHIDLYQFHHVDRRTPFDEIWQAMDTLVQQGKILYAGSSNFPGYKIAQANEAAARRGSLGLVSEQCLYNLAERRAEMEVIPAAEEYGLGVIAWSPLHGGLLGGAIRKEREGGGSRTNDGRSGDALANSTIRAQVQAYEDLLEKHGLEPGEVALAWLLTRPGLTGPIVGPRTDEQLASAVRAVELELPQELLTALDEIFPGPGPSPEAFAW
>NC_020990.1|WP_003950027.1|2707191_2710425_-|hypothetical-protein
MTHPTPAQEGKDPFGTARRRRTVLDSWAASPARFREDANAEEDLALGGYRDRLIVELAQNAADAASRAGTDGRLRLTLHESAGTHVLAAANTGAPLDATGVESLSTLRASAKRPATGTATGAAPGAGPSVGRFGVGFAAVLAVSDEPAVLSRTGGVRWDLAQAREAAREVARHSPGLGDELIRRDDHVPLLRLPFPAEGIPPEGYDTVVVLPLRDAAAQDLAERLLAGVDDALLLALPGLTEIVVETPESTRVLRRRDEEPYVVIEESTGGSGATGAGATGTPAETRRWRTATSGGPLDAPLLADRPVEERLRPYWSVVWAVPVDAEGAPVRPATAPVVHAPTPSDEPLGVPALLIASFPLDTARRHVAPGPLTDFLVGRAAEAYAGLLGAWRPVGPAAVGLVPGPLGLAAVDGAVRAAVLDLLPRTAFLPPALPPAGPDEEPDTDVPLLRADRPEALRPIEAELVEGAGEATVRVLAEVLPTLLPAGLERRAELRTLGVGRLSLGEAIDRLAGVERSPAWWYRLYDSLAGVDPDRLQGLPVPLAAGSTAGSPRQVLLPGPAEDGPRPAALARLGLKVAHPEAAHPLLEKLGALPATPRAVLRTPQVRAAVAESLEGDGYALRDDAPDAEELAELVLTLARDAELAPGDEPWLGALALPDEDGELSPAGELVLPGGEFASVMREGALAAVDEEWAGRWGEQPLAACGVLARFTLVRATDVVLDPDELEPRDTDFAEPDDVGLLDAVDVWCEDVLDQLPDGPVPPVATEITAVRDLDLVDDDRWPEALALLSRPPLRDALTQPVRVLLPDGTTESVRPYTAWWLRGHPVLDGRRPAGLRAASGDALLAGLYDEVDAAGFDDALVLRALGVRTTAAALLDEPGGAAELLDRLADPDREVSARQLHALYGLLAELDPEEVTLPDELPAVADGVVTVVDARDALVADAPDLLPFAAGRPLLPVAPALAARLAELLQVGRLSEAVRVTPAGEGVEYPVPEAVRELLGDGVPASYREHDELLADGVELDWHLTASGVLHAATLEGVAAGLAWGAGQWPRRFEVAALLEDPSRRAELSRDRWFD
>NC_020990.1|WP_015507347.1|2711582_2712443_-|DUF3027-domain-containing-protein
MSAATTRSRTPDRLCAEAVDLARSMAEETAAPGVVGEHLAVTADGDRVATHYFACHDPGYRGWRWAVTVARASRAKYVTVDESVLLPGPDALLAPEWVPWSERLRPGDLGPGDLLPTEADDLRLEPGWIADEEPPPNSAVSADMAELVEAEDASLSAGPPADLPLAPERGSVASVAEELGLRRSRVLSRYGLLDAAERWEAQFGAESAMAQAAPAPCVSCGFLLPLAGSLRQAFGICANAYSPADGHVVSLAYGCGGHSEAAVMPTPPRPPDPALDETRLDPLPLD
>NC_020990.1|WP_015507348.1|2712854_2714333_+|MFS-transporter
MRRAARVVGRALRTPVTGPARGIRKVTHAQGAGESGLGRLIELHGVNGAGDVMITVALASTVFFSVPTDEARGRVALYLAVTMLPFTLLAPVVGPLLDRLPHGRRAAMAGSMLARAVLALVLSGAVATGSLEMYPAALGVLVASKAYGVVRSAVVPRLLPQGFSLVKANSRVTLGGLLATGVAAPVGAGLQMIGPGWPLYGACLLFLGGAFLSFRLPPKVDSARGERRALLAADEQHLAAAVDARWDPVTTDDKTDDKTDDKTDSTDNKEEEKDRDGERGDGERGKGKERRRKGPGLRTVGPAVTHALAANACVRCQSGFLIFFLAFLLREHPLTGQSAAVSLAVVGVAAGAGNALGTAVGAWLRARAPEVIIVTVVGALVAVAVSAAVFFGAAVVAVLGAVAGFTQALAKLSLDALIQRDVPELVRTSAFARSETLLQMAWVVGGAIGIALPLRGPLGLSVGALIVALGWLTTVRALLASARRGASHPRVA
>NC_020990.1|WP_008415563.1|2714362_2714887_+|hypothetical-protein
MTSLPRGGAARQFSPATRRGFAVLGAVSAGLLVLSACDKPTAVATVTIGSDSVNSEATCWNGGSKIDEKKLQQCLQDKGEGDSGDGAEVKTVKVDTEADVHIGVDPKIADKGWTILMNGQPLTDASNKTFRTIPGSVFFNQQYGASGDSTVLSILENDGSSATGLWSFKLEKES
>NC_020990.1|WP_015507349.1|2714907_2715633_+|futalosine-hydrolase
MRLLVATAVPPERDAVARAFGAPDTPEETALPGAVLLRTPGADVLAAGVGPAAAASATSAALTAARLAGNPYDLVVSAGIGGGFAERAPVGAVVVADRILAADLGAETPDGFVPVTGLGFGTDAHVPPAALVEAAREAGLVPGAVLTVSTVTGSADRTAELLARHPSAVAEAMEGFGVAEAAAAHGVPVLEIRAISNAIGPRDRDAWRIPAALTALTSAFVRLAPAEAGSPFALARARLVP
>NC_020990.1|WP_003950022.1|2715700_2716594_+|1,4-dihydroxy-6-naphthoate-synthase
MSESGTGGVQGTADEAGRLSIAYSPCPNDTFVFDAVAHGRVPGAPALDVTFADIDLTNGMAERGAYDVLKVSYAALPWLLDEYALLPCGGALGRGCGPLVLTREASLPGALAGRTVAVPSERSTAYLLFRLWAADQVPGGVGEIVVMPFHEIMPAVRDGKVDAGLVIHEARFTYQNYGLHKLADMGEHWEATTGLPIPLGAIIARRSLGAERLTALAQALRTSVRMAWDDPAASRPYVLAHAQEMDADVADQHIGLYVNEFTADLGEDGYAAVRGLLTRAAAEGLVPPLAPDALRFP
>NC_020990.1|WP_003950021.1|2716710_2717094_-|cold-shock-protein
MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPAGVEALKPGQRVEFGVVAGQRGDQALSVVLLDPAPSVAAAQRRKPDELASIVQDLTTVLENVSRSLERGRYPDRASGAKVAGMLRAVADQLDV
>NC_020990.1|WP_003950020.1|2717235_2717487_+|hypothetical-protein
MSDTTQQTPAPGDRLVKTGGIVFIIGALATLVTVAPLFLGSDPFPTAAYLVSMLMGVGFLIAGAGLVRQIAAQRRETRAAVEG
>NC_020990.1|WP_051085198.1|2717795_2718500_+|response-regulator-transcription-factor
MIHSSGVLRSALVALLERERFQVTGASGFSRASSTGAPGTPGAPATVTVVDGSCPVGAAHLERRSLQGSAKEPTHATPALAAARPGLGLAGAGAERAGIGLAGASRGRAALVVLAGAEHPGVLRLAYAAGALGLVDRDGPANHLATAIRLAAGGGRYVDDGLAMSLLRAMDMPLSPREVRVLSRAAQGDSVAEIARGLCLSHGTVRNYIASATRKVGARNRVDAIRISRAAGWV
>NC_020990.1|WP_003950018.1|2719084_2721016_-|ABC-transporter-ATP-binding-protein
MTRPRHTDGAPSPLLRPALTFARRRKGPLGALGAWSLLESARTFLTGYAVARALDDGFLAGDVRAGLLWLLALAAAALAGGFADAGVFRALGGVIEPLRDSLVRRVVRATLTRAVASPTPADTARVSRLTAQTEIARDAAGGVLLTVRSFLFTSAGAFTGLAALSPRLLPLVLIPLAAGLALFAATLRPMAARQRDLLDADEHLAAFAGRTDHAARDIAATGAAPLVTAEAAPLITAEATAASALARWSAVRVTALGLAAHLPVATLLLAAPTLLSTGLTPGELLAALTYVTTALLPAVNALLTALGAAGSRLLVVLHRLLGEEADAADVREEQAHALRADDGPRAPGAWSKGKADDEVPAIPVPSLPPEPVHGPEPFHAEPSPPGPRPTRGPRPTRPALPAATLRGLTFAYGPDAAPVLDHLDLTVEPGEHLLVVGPSGAGKSTLLALLAGTAHPRHGQIHLAGHTARHARTLGTAARVLVPQEPYIFEAPLHDNLTYLAPNAPAPRITEAIDTFTLAPLAADPARPLRPDHLTPSERRRIALARAWLTPTPLLLLDEPTAHLDAGARAATELAFASHPATVITVSHHFPAPEPGQRVLLLDGATPYLGTHASLLRESALYGELAAGLGEPSAMGSRGTAST

Crispr_ID: NC_020990_12

• CRISPR_ID: NC_020990_12
• CRISPR_location: 2711374-2711481
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_12

Consensus_repeat	Method
CAGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NC_020990_12

>12.1|2711398|60|NC_020990|CRISPRCasFinder
TCGGTGACCCGCAGGGTCACGGGCAGGCACGCAGGGGCGGAGCCCAGCCACACCGCATCC

CRISPR arrays and Neighbor proteins around NC_020990_12

CRISPR arrays

The CRISPR arrays of NC_020990_12

>merge|NC_020990|12|2711374-2711481|CRISPRCasFinder
CAGCCCGGCCGGCGCTTGAGGCCATCGGTGACCCGCAGGGTCACGGGCAGGCACGCAGGGGCGGAGCCCAGCCACACCGCATCCCAGCCCGGCCGGCGATTGAGGCCA

>NC_020990|12|10|2711374-2711481|CRISPRCasFinder
CAGCCCGGCCGGCGCTTGAGGCCA	TCGGTGACCCGCAGGGTCACGGGCAGGCACGCAGGGGCGGAGCCCAGCCACACCGCATCC
CAGCCCGGCCGGCGATTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003950033.1|2698618_2698882_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950021.1|2716710_2717094_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NC_020990.1|WP_008415563.1|2714362_2714887_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950022.1|2715700_2716594_+|1,4-dihydroxy-6-naphthoate-synthase	unknown	unknown	gnl|CDD|270353
NC_020990.1|WP_003950018.1|2719084_2721016_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|225183
NC_020990.1|WP_003950031.1|2700758_2701025_+|DUF2530-domain-containing-protein	unknown	unknown	gnl|CDD|378488
NC_020990.1|WP_003950032.1|2698955_2700401_-|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NC_020990.1|WP_003950020.1|2717235_2717487_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_010643325.1|2703737_2704598_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950027.1|2707191_2710425_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507347.1|2711582_2712443_-|DUF3027-domain-containing-protein	unknown	unknown	gnl|CDD|378605
NC_020990.1|WP_015507348.1|2712854_2714333_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_020990.1|WP_003950035.1|2696532_2697879_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_020990.1|WP_015507349.1|2714907_2715633_+|futalosine-hydrolase	unknown	unknown	gnl|CDD|236194
NC_020990.1|WP_051085198.1|2717795_2718500_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_020990.1|WP_003950028.1|2704943_2706203_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NC_020990.1|WP_003950034.1|2697982_2698420_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_020990.1|WP_003950036.1|2695863_2696454_-|RNA-2',3'-cyclic-phosphodiesterase	unknown	unknown	gnl|CDD|274058
NC_020990.1|WP_008415575.1|2721012_2722908_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_020990.1|WP_003950030.1|2701193_2703632_+|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl|CDD|319795

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003950022.1|2715700_2716594_+|1,4-dihydroxy-6-naphthoate-synthase	gnl|CDD|270353	cd13635, PBP2_Ttha1568_Mqnd, A menaquinone biosynthetic enzyme exhibits the type 2 periplasmic-binding protein fold. This group includes Ttha1568 (MqnD) from Thermus thermophilies HB8, an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. Ttha1568 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.21409e-142
NC_020990.1|WP_003950018.1|2719084_2721016_-|ABC-transporter-ATP-binding-protein	gnl|CDD|225183	COG2274, SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms].	1.62769e-36
NC_020990.1|WP_003950031.1|2700758_2701025_+|DUF2530-domain-containing-protein	gnl|CDD|378488	pfam10745, DUF2530, Protein of unknown function (DUF2530). This family of proteins with unknown function appears to be restricted to mycobacteria.	0.00433448
NC_020990.1|WP_003950032.1|2698955_2700401_-|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.89915e-107
NC_020990.1|WP_003950021.1|2716710_2717094_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	5.07314e-27
NC_020990.1|WP_015507347.1|2711582_2712443_-|DUF3027-domain-containing-protein	gnl|CDD|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.47353e-109
NC_020990.1|WP_015507348.1|2712854_2714333_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.23737e-18
NC_020990.1|WP_003950035.1|2696532_2697879_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.218e-81
NC_020990.1|WP_015507349.1|2714907_2715633_+|futalosine-hydrolase	gnl|CDD|236194	PRK08236, PRK08236, hypothetical protein; Provisional.	6.12362e-66
NC_020990.1|WP_051085198.1|2717795_2718500_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	9.25685e-26
NC_020990.1|WP_003950028.1|2704943_2706203_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	4.41532e-72
NC_020990.1|WP_003950034.1|2697982_2698420_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.04287e-20
NC_020990.1|WP_003950036.1|2695863_2696454_-|RNA-2',3'-cyclic-phosphodiesterase	gnl|CDD|274058	TIGR02258, UPF0097_protein_AF_2157, 2'-5' RNA ligase. This protein family consists of bacterial and archaeal proteins with two tandem copies of Pfam domain pfam02834. Members for which activity has been measured perform a reversible, ATP-independent 2'-5'-ligation of what is presumably a non-phyiological substrate: half-tRNA splice intermediates from an intron-containing yeast tRNA. The physiological substrate(s) in prokaryotes may include small 2'-5'-link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles. [Transcription, RNA processing].	3.86408e-35
NC_020990.1|WP_008415575.1|2721012_2722908_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.64742e-83
NC_020990.1|WP_003950030.1|2701193_2703632_+|HAD-IC-family-P-type-ATPase	gnl|CDD|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0

Protein sequences

>NC_020990.1|WP_003950027.1|2707191_2710425_-|hypothetical-protein
MTHPTPAQEGKDPFGTARRRRTVLDSWAASPARFREDANAEEDLALGGYRDRLIVELAQNAADAASRAGTDGRLRLTLHESAGTHVLAAANTGAPLDATGVESLSTLRASAKRPATGTATGAAPGAGPSVGRFGVGFAAVLAVSDEPAVLSRTGGVRWDLAQAREAAREVARHSPGLGDELIRRDDHVPLLRLPFPAEGIPPEGYDTVVVLPLRDAAAQDLAERLLAGVDDALLLALPGLTEIVVETPESTRVLRRRDEEPYVVIEESTGGSGATGAGATGTPAETRRWRTATSGGPLDAPLLADRPVEERLRPYWSVVWAVPVDAEGAPVRPATAPVVHAPTPSDEPLGVPALLIASFPLDTARRHVAPGPLTDFLVGRAAEAYAGLLGAWRPVGPAAVGLVPGPLGLAAVDGAVRAAVLDLLPRTAFLPPALPPAGPDEEPDTDVPLLRADRPEALRPIEAELVEGAGEATVRVLAEVLPTLLPAGLERRAELRTLGVGRLSLGEAIDRLAGVERSPAWWYRLYDSLAGVDPDRLQGLPVPLAAGSTAGSPRQVLLPGPAEDGPRPAALARLGLKVAHPEAAHPLLEKLGALPATPRAVLRTPQVRAAVAESLEGDGYALRDDAPDAEELAELVLTLARDAELAPGDEPWLGALALPDEDGELSPAGELVLPGGEFASVMREGALAAVDEEWAGRWGEQPLAACGVLARFTLVRATDVVLDPDELEPRDTDFAEPDDVGLLDAVDVWCEDVLDQLPDGPVPPVATEITAVRDLDLVDDDRWPEALALLSRPPLRDALTQPVRVLLPDGTTESVRPYTAWWLRGHPVLDGRRPAGLRAASGDALLAGLYDEVDAAGFDDALVLRALGVRTTAAALLDEPGGAAELLDRLADPDREVSARQLHALYGLLAELDPEEVTLPDELPAVADGVVTVVDARDALVADAPDLLPFAAGRPLLPVAPALAARLAELLQVGRLSEAVRVTPAGEGVEYPVPEAVRELLGDGVPASYREHDELLADGVELDWHLTASGVLHAATLEGVAAGLAWGAGQWPRRFEVAALLEDPSRRAELSRDRWFD
>NC_020990.1|WP_003950028.1|2704943_2706203_+|cytochrome-P450
MPSSAPPEQEPLVLDPTGADPHAEHRALHARGPATRVDVLGVPAWSVSDPALLRALLTSPDVSKDGRAHWPAFAETVQSWPLALWVAVRNMFTSYGADHRRLRRIIAPAFSARRVEAVRPVVERITAGLLDDLAALPPDAPVDLREKLAYPLPVAVIGHLMGVPEERYAHFRAVVDGVFDTTLGREEAAANTDALYVVLDELIATRRAEPGDDLTPLLLATPDEEGAEPALSHEELRDTLLLVISAGYETTVHVIDQAVHALLTVDGQLDLVRSGQVGWGDVVEETLRHESAVKHLPLRYAVRDIPLPDGRTIARGEAILASYAAANRHPGWHDDADVFDAGRLSKEHLAFGHGVHFCVGAPLARLEVEVCLRLLFARFPGLALDLPAEGLPPFPSLISNGHRNLPVWLHGGALGEGPG
>NC_020990.1|WP_010643325.1|2703737_2704598_-|hypothetical-protein
MRIRATVAVVSGALALSALTGAAAQAAPGPDRERIQVPTAESVFGKQATAKGKGFKAAAVPKISKVTVNGGKDIVLGTTKAKTFSVSITASHASNIGDAYAYFWHGSTYETADGVFIPNEEYASCKASSTTTSTCKLTFTVDPQWELINDLAGSWNVGVGALAADDSDFAWNDKHSKTRVQRYSKLVVNATPEPVKKGKTLTVNGTLSRANWDTWKYAGYTQQSVKLQFKKKGAASYTTVKTVKSGSKGALKTTVKAASDGYWRWSFAGTSTTPAINSTADFVDVK
>NC_020990.1|WP_003950030.1|2701193_2703632_+|HAD-IC-family-P-type-ATPase
MTQRGQVDTGGSDSGNSRIDTGAEPDAAPPAVPPEPGLSSAEVAEAVARGEVNDVPVRSSRSLAEIARANIFTRFNAIIGVLWVIMLFVAPIQDSLFGFVIVANTGIGIFQEWRAKRTLDGLAVIGEAKPTVRRDGRPGEISTSEIVLGDLIEIGPGDKIVVDGEVREADGLEVDESLLTGEADPVVKRPGDEVMSGSFVTAGGGAFRATKVGREAYAAQLAEEASRFTLVHSELRSGISTILKYVTWMMVPTAIGLVVSQLVVRDNDFKNAVARTVGGIVPMVPEGLVLLTSVAFAIGVIRLGRKQCLVQELPAIEGLARVDTVCLDKTGTLTEGGMDVQAIRPLGGADEAYVRRVLGALGAGDPRPNASLQAVIDACPAPEGWRTTGTLPFSSARKYSGASLDEGDATHRTWLLGAPDVLLRPGAEALAETDALNERGLRVLLLSRAAGGLDGPDPGAGAEPTALVVLEQRLRPDAADTLRYFEDQHVAAKVISGDNAVSVGAVAGKLGLPGAERTYDARKLPKEPEALADTLDENTVFGRVTPQQKRDMVGALQAHGHTVAMTGDGVNDVLALKDADIGVSMGSGSEATRAVAQIVLLNNSFSTLPSVVAEGRRVIGNITRVATLFLVKTVYSVLLAILVVLSQTEYPFLPRHLTLLSTLTIGVPAFFLALAPNKERAQPHFVKRVMRYAIPGGVIAALATFTTYMTARAYYTGPDSLPAETSAATLTLFLVSLWVLAIIARPYTWWRVGLVATMAGAFLVVLAVPWLQDFFALRLVGSVMPWAAVGIAVIAAALIEVVWRLVDRRLPV
>NC_020990.1|WP_003950031.1|2700758_2701025_+|DUF2530-domain-containing-protein
MKKWTPRHEAPEPLEGPVVATITGGTILWFVLFLAQLPFYGWYDDRGHTWWIWTCLAGAGLGCLGVWYVRRREAALKRAATAAPQPGS
>NC_020990.1|WP_003950032.1|2698955_2700401_-|NCS2-family-permease
MPTSAPAQDATSEQPNPPSGALDRYFKITERGSTLSREVRGGFATFFAMAYIIVLNPIILGSAKDMYGHQLDNGQLVTATVLTAALTTLLMGVIGNVPVALAAGLGVNTVVALQLAPRMSWPDAMGMVVLAGFVVMLLVATGLRERVMSAVPLGLRKGIAIGIGLFIMLIGLVDAGFVSRIPDAAQTTVPLQLGADGHLNGWTVLVFVLGVLLTLALMVRKVPGAILISIVAMTVLALIINAVADIPSWGLTTPEWPGNPVATPDFGLIGQVSLFGGFAKVGLLTGILFVFTVLLSCFFDAMGTIMAVGDEAELTDAQGNMPGINKVLFVDGIAVAAGGASSSSATTCFVESTAGVGEGARTGFANIVTGGLFAIGLFLTPVVTMVPSQAATPALVAVGFLILSGSIGAIDWTDFTIAIPAFITFMMMPFTYSITNGIGMGFISFCVLRLAAGRGRSVPAAMYVVSGVFAFYYLMPALGLT
>NC_020990.1|WP_003950033.1|2698618_2698882_+|hypothetical-protein
MDTHVLSLRMDSELFERLRGHAARRGMSVQDYVVRTMIRDDFDQRFQTAVEETEKFYGDEDGGAPRAGEVAEEPARDGAVNGAARPT
>NC_020990.1|WP_003950034.1|2697982_2698420_-|MarR-family-transcriptional-regulator
MPDLTHGEDADAVNALRSSVMRLSRRLKHQRVDESLSPTEMSVLGTLARCGTATPGELARKEHVQPPSMTRIVALLEAKGLVRLEPHPEDRRQKVVTQTEEAEAMLEESRSKRNAWLASLAAELDEEEWAKVRAAAPVLEKLAHL
>NC_020990.1|WP_003950035.1|2696532_2697879_-|MFS-transporter
MSTGPGADSAPAPAAHDSTPPAPKQSMFSSLKIHNYRLFFTGQVISNTGTWMQRIAQDWLVLTLTGSSAAVGVTTALQFLPMLLFGLYGGVLVDRLPKRPLLLFTQSAMGLTGLALAALTLTGHVQVWHVYVTAFVLGLVTVVDNPARQTFVSEMVGPRQLANAVSLNSANFQSARLVGPAVAAVLISAVGSGYAFLINGLSFAAPIAGLLMMRMGDLHKAPRTPRGKGQLREGLRYVAGRPDLIWPIVLVGFIGTFGFNFPIWLSAFADKIFDGGPGMYGTLNTLIAAGSLAGALLAARRGAGRLRLLVAAAAAFGVLEIVAAFAPSVWIFAVLMVLTGMFGLTVNVTANSYVQMATEPQMRGRVMALFMMVFTGGTPLGAPLLGWITDEYGARTGFAVGGAISLLAALAVGLILARVGGLKVKVDLRRGRKHIRFVPDEKRLAPAA
>NC_020990.1|WP_003950036.1|2695863_2696454_-|RNA-2',3'-cyclic-phosphodiesterase
MASPAPRPRLFVAVVPPDAVLAELRRATAALDALPGAGRLRPTEAGGRHVTLAFLGACDPGHLDGLAARLARAAHRTAPFPLALRGAGHFGDRVLWARPDGDLDALARLADRVRAAATRAGLPPDAEHAFRPHLTLARVRPGPPLRLAPFAEALAQLAAGPWQADEVRLLRSVPPPGGVPGARPTYATEGRWPLGG
>NC_020990.1|WP_015507347.1|2711582_2712443_-|DUF3027-domain-containing-protein
MSAATTRSRTPDRLCAEAVDLARSMAEETAAPGVVGEHLAVTADGDRVATHYFACHDPGYRGWRWAVTVARASRAKYVTVDESVLLPGPDALLAPEWVPWSERLRPGDLGPGDLLPTEADDLRLEPGWIADEEPPPNSAVSADMAELVEAEDASLSAGPPADLPLAPERGSVASVAEELGLRRSRVLSRYGLLDAAERWEAQFGAESAMAQAAPAPCVSCGFLLPLAGSLRQAFGICANAYSPADGHVVSLAYGCGGHSEAAVMPTPPRPPDPALDETRLDPLPLD
>NC_020990.1|WP_015507348.1|2712854_2714333_+|MFS-transporter
MRRAARVVGRALRTPVTGPARGIRKVTHAQGAGESGLGRLIELHGVNGAGDVMITVALASTVFFSVPTDEARGRVALYLAVTMLPFTLLAPVVGPLLDRLPHGRRAAMAGSMLARAVLALVLSGAVATGSLEMYPAALGVLVASKAYGVVRSAVVPRLLPQGFSLVKANSRVTLGGLLATGVAAPVGAGLQMIGPGWPLYGACLLFLGGAFLSFRLPPKVDSARGERRALLAADEQHLAAAVDARWDPVTTDDKTDDKTDDKTDSTDNKEEEKDRDGERGDGERGKGKERRRKGPGLRTVGPAVTHALAANACVRCQSGFLIFFLAFLLREHPLTGQSAAVSLAVVGVAAGAGNALGTAVGAWLRARAPEVIIVTVVGALVAVAVSAAVFFGAAVVAVLGAVAGFTQALAKLSLDALIQRDVPELVRTSAFARSETLLQMAWVVGGAIGIALPLRGPLGLSVGALIVALGWLTTVRALLASARRGASHPRVA
>NC_020990.1|WP_008415563.1|2714362_2714887_+|hypothetical-protein
MTSLPRGGAARQFSPATRRGFAVLGAVSAGLLVLSACDKPTAVATVTIGSDSVNSEATCWNGGSKIDEKKLQQCLQDKGEGDSGDGAEVKTVKVDTEADVHIGVDPKIADKGWTILMNGQPLTDASNKTFRTIPGSVFFNQQYGASGDSTVLSILENDGSSATGLWSFKLEKES
>NC_020990.1|WP_015507349.1|2714907_2715633_+|futalosine-hydrolase
MRLLVATAVPPERDAVARAFGAPDTPEETALPGAVLLRTPGADVLAAGVGPAAAASATSAALTAARLAGNPYDLVVSAGIGGGFAERAPVGAVVVADRILAADLGAETPDGFVPVTGLGFGTDAHVPPAALVEAAREAGLVPGAVLTVSTVTGSADRTAELLARHPSAVAEAMEGFGVAEAAAAHGVPVLEIRAISNAIGPRDRDAWRIPAALTALTSAFVRLAPAEAGSPFALARARLVP
>NC_020990.1|WP_003950022.1|2715700_2716594_+|1,4-dihydroxy-6-naphthoate-synthase
MSESGTGGVQGTADEAGRLSIAYSPCPNDTFVFDAVAHGRVPGAPALDVTFADIDLTNGMAERGAYDVLKVSYAALPWLLDEYALLPCGGALGRGCGPLVLTREASLPGALAGRTVAVPSERSTAYLLFRLWAADQVPGGVGEIVVMPFHEIMPAVRDGKVDAGLVIHEARFTYQNYGLHKLADMGEHWEATTGLPIPLGAIIARRSLGAERLTALAQALRTSVRMAWDDPAASRPYVLAHAQEMDADVADQHIGLYVNEFTADLGEDGYAAVRGLLTRAAAEGLVPPLAPDALRFP
>NC_020990.1|WP_003950021.1|2716710_2717094_-|cold-shock-protein
MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPAGVEALKPGQRVEFGVVAGQRGDQALSVVLLDPAPSVAAAQRRKPDELASIVQDLTTVLENVSRSLERGRYPDRASGAKVAGMLRAVADQLDV
>NC_020990.1|WP_003950020.1|2717235_2717487_+|hypothetical-protein
MSDTTQQTPAPGDRLVKTGGIVFIIGALATLVTVAPLFLGSDPFPTAAYLVSMLMGVGFLIAGAGLVRQIAAQRRETRAAVEG
>NC_020990.1|WP_051085198.1|2717795_2718500_+|response-regulator-transcription-factor
MIHSSGVLRSALVALLERERFQVTGASGFSRASSTGAPGTPGAPATVTVVDGSCPVGAAHLERRSLQGSAKEPTHATPALAAARPGLGLAGAGAERAGIGLAGASRGRAALVVLAGAEHPGVLRLAYAAGALGLVDRDGPANHLATAIRLAAGGGRYVDDGLAMSLLRAMDMPLSPREVRVLSRAAQGDSVAEIARGLCLSHGTVRNYIASATRKVGARNRVDAIRISRAAGWV
>NC_020990.1|WP_003950018.1|2719084_2721016_-|ABC-transporter-ATP-binding-protein
MTRPRHTDGAPSPLLRPALTFARRRKGPLGALGAWSLLESARTFLTGYAVARALDDGFLAGDVRAGLLWLLALAAAALAGGFADAGVFRALGGVIEPLRDSLVRRVVRATLTRAVASPTPADTARVSRLTAQTEIARDAAGGVLLTVRSFLFTSAGAFTGLAALSPRLLPLVLIPLAAGLALFAATLRPMAARQRDLLDADEHLAAFAGRTDHAARDIAATGAAPLVTAEAAPLITAEATAASALARWSAVRVTALGLAAHLPVATLLLAAPTLLSTGLTPGELLAALTYVTTALLPAVNALLTALGAAGSRLLVVLHRLLGEEADAADVREEQAHALRADDGPRAPGAWSKGKADDEVPAIPVPSLPPEPVHGPEPFHAEPSPPGPRPTRGPRPTRPALPAATLRGLTFAYGPDAAPVLDHLDLTVEPGEHLLVVGPSGAGKSTLLALLAGTAHPRHGQIHLAGHTARHARTLGTAARVLVPQEPYIFEAPLHDNLTYLAPNAPAPRITEAIDTFTLAPLAADPARPLRPDHLTPSERRRIALARAWLTPTPLLLLDEPTAHLDAGARAATELAFASHPATVITVSHHFPAPEPGQRVLLLDGATPYLGTHASLLRESALYGELAAGLGEPSAMGSRGTAST
>NC_020990.1|WP_008415575.1|2721012_2722908_-|ABC-transporter-ATP-binding-protein
MTAAPADAARARATPAPPPAEGRLLREAVRRGRGPAALVLAATALGAAAAVTLPLALGRAVDLLIARADAGSWVLLCTALIATEVATDALVARTGGRTGAATTAWLRRRALAGFLAAPPAATTGTGLPTRLTANALDAGTAPVAAATAAAAGLAPLGGLAGLFLVDPWAGAAFVCGVPLLLLILRALLRDGRAALTTYQEEQGRMARLLTGALSGAATIAAAGTVRAEERRVLAPLAGMRAAGERTWRVQGRAAGLSGALMPLLVAAVLAVGGVRLVAGHLTPGDLLALSRYAVLAAGAGALAGAVNGWVRAKAGTARVETVTALPPTPHGTRDLPPHGDGTLALHGVHVTRDGVPLLDSVTLTLPGGTTTALVGPSGSGKSLLAAVAGRLTDPDQGTVLLDGTDLRTLSADTLRHAVAYAFERPALYGATIADAVACGPLPEPDLRRALRRAAADTFTDRLPQGPRTPLPEAPLSGGELQRLGLARAFSRPTRLLILDDATSSLDTVTAHLVARALTDTPGTRLTITHRLTTAAQSDQVVWLDGGRIRGTGPHSVLWRDPAYRAVFGAGAGGDAGAGADTVTDTEARRRSDVRTDVTGDVRTELPTDMRTDLHTGIRTDPRVDTGTGAAE

Crispr_ID: NC_020990_13

• CRISPR_ID: NC_020990_13
• CRISPR_location: 2718782-2719054
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NC_020990_13

Consensus_repeat	Method
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	PILER-CR
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	CRISPRCasFinder
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	CRT

spacers of NC_020990_13

>13.1|2718811|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT
AGTTGGCACCGCCGCACGATGATCACAACCCA
>13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT
GCCGAGGGGTTGTGGATGAGGCCGCCGCGCTG
>13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT
TTCGGGCTCGCCACCTCGACCGCGAGCACAGT
>13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT
TCGTCGAGGGTGGCGTTCAGGACCGTGACGAT

CRISPR arrays and Neighbor proteins around NC_020990_13

CRISPR arrays

The CRISPR arrays of NC_020990_13

>merge|NC_020990|13|2718782-2719054|PILER-CR,CRISPRCasFinder,CRT
CTGCTCCCCGCGCGTGCGGGGTTGGTCCCAGTTGGCACCGCCGCACGATGATCACAACCCACTGCTCCCCGCGCGTGCGGGGTTGGTCCCGCCGAGGGGTTGTGGATGAGGCCGCCGCGCTGCTGCTCCCCGCGCGTGCGGGGTTGGTCCCTTCGGGCTCGCCACCTCGACCGCGAGCACAGTCTGCTCCCCGCGCGTGCGGGGTTGGTCCCTCGTCGAGGGTGGCGTTCAGGACCGTGACGATCTGCTCCCCGCGCGTGCGGGGTTGGTTCC

>NC_020990|13|4|2718782-2719054|PILER-CR
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	AGTTGGCACCGCCGCACGATGATCACAACCCA
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	GCCGAGGGGTTGTGGATGAGGCCGCCGCGCTG
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	TTCGGGCTCGCCACCTCGACCGCGAGCACAGT
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	TCGTCGAGGGTGGCGTTCAGGACCGTGACGAT
CTGCTCCCCGCGCGTGCGGGGTTGGTTCC

>NC_020990|13|11|2718782-2719054|CRISPRCasFinder
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	AGTTGGCACCGCCGCACGATGATCACAACCCA
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	GCCGAGGGGTTGTGGATGAGGCCGCCGCGCTG
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	TTCGGGCTCGCCACCTCGACCGCGAGCACAGT
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	TCGTCGAGGGTGGCGTTCAGGACCGTGACGAT
CTGCTCCCCGCGCGTGCGGGGTTGGTTCC

>NC_020990|13|2|2718782-2719054|CRT
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	AGTTGGCACCGCCGCACGATGATCACAACCCA
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	GCCGAGGGGTTGTGGATGAGGCCGCCGCGCTG
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	TTCGGGCTCGCCACCTCGACCGCGAGCACAGT
CTGCTCCCCGCGCGTGCGGGGTTGGTCCC	TCGTCGAGGGTGGCGTTCAGGACCGTGACGAT
CTGCTCCCCGCGCGTGCGGGGTTGGTTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003950013.1|2727058_2727913_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224045
NC_020990.1|WP_003950022.1|2715700_2716594_+|1,4-dihydroxy-6-naphthoate-synthase	unknown	unknown	gnl|CDD|270353
NC_020990.1|WP_003950018.1|2719084_2721016_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|225183
NC_020990.1|WP_015507352.1|2729003_2730068_-|iron-ABC-transporter-permease	unknown	unknown	gnl|CDD|376439
NC_020990.1|WP_003950021.1|2716710_2717094_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NC_020990.1|WP_003950020.1|2717235_2717487_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_008415563.1|2714362_2714887_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003950027.1|2707191_2710425_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507347.1|2711582_2712443_-|DUF3027-domain-containing-protein	unknown	unknown	gnl|CDD|378605
NC_020990.1|WP_008415578.1|2723066_2723198_-|SapB/AmfS-family-lantipeptide	unknown	unknown	gnl|CDD|380211
NC_020990.1|WP_015507353.1|2730200_2730887_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|223620
NC_020990.1|WP_015507349.1|2714907_2715633_+|futalosine-hydrolase	unknown	unknown	gnl|CDD|236194
NC_020990.1|WP_051085198.1|2717795_2718500_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_020990.1|WP_003950028.1|2704943_2706203_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NC_020990.1|WP_008415575.1|2721012_2722908_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_020990.1|WP_015507351.1|2723287_2725867_-|protein-kinase/lanthionine-synthetase-C-family-protein	unknown	unknown	gnl|CDD|271199
NC_020990.1|WP_003950012.1|2727909_2729007_-|iron-ABC-transporter-permease	unknown	unknown	gnl|CDD|376439
NC_020990.1|WP_003950014.1|2726084_2727062_-|iron-siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238566
NC_020990.1|WP_015507348.1|2712854_2714333_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_020990.1|WP_015507354.1|2732125_2733190_+|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl|CDD|377085

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003950013.1|2727058_2727913_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	1.11996e-133
NC_020990.1|WP_003950022.1|2715700_2716594_+|1,4-dihydroxy-6-naphthoate-synthase	gnl|CDD|270353	cd13635, PBP2_Ttha1568_Mqnd, A menaquinone biosynthetic enzyme exhibits the type 2 periplasmic-binding protein fold. This group includes Ttha1568 (MqnD) from Thermus thermophilies HB8, an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. Ttha1568 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.21409e-142
NC_020990.1|WP_003950018.1|2719084_2721016_-|ABC-transporter-ATP-binding-protein	gnl|CDD|225183	COG2274, SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms].	1.62769e-36
NC_020990.1|WP_003950021.1|2716710_2717094_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	5.07314e-27
NC_020990.1|WP_015507352.1|2729003_2730068_-|iron-ABC-transporter-permease	gnl|CDD|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	7.97077e-83
NC_020990.1|WP_015507347.1|2711582_2712443_-|DUF3027-domain-containing-protein	gnl|CDD|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.47353e-109
NC_020990.1|WP_008415575.1|2721012_2722908_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.64742e-83
NC_020990.1|WP_015507353.1|2730200_2730887_+|HAD-family-hydrolase	gnl|CDD|223620	COG0546, Gph, Predicted phosphatases [General function prediction only].	1.16854e-24
NC_020990.1|WP_015507349.1|2714907_2715633_+|futalosine-hydrolase	gnl|CDD|236194	PRK08236, PRK08236, hypothetical protein; Provisional.	6.12362e-66
NC_020990.1|WP_051085198.1|2717795_2718500_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	9.25685e-26
NC_020990.1|WP_003950028.1|2704943_2706203_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	4.41532e-72
NC_020990.1|WP_008415578.1|2723066_2723198_-|SapB/AmfS-family-lantipeptide	gnl|CDD|380211	NF033212, SapB_AmfS_lanti, SapB/AmfS family lantipeptide. Members of this family are class III lantipeptide precursors. These typically are short peptides, encoded next to the gene for the lantipeptide synthetase that creates the characteristic lanthionine (or beta-methyl lanthionine) bridges for which these natural products are named. Members of this family include SapB and AmfS, which are considered morphogens rather than antibiotics. Members also include labionin-containing peptides such labyrinthopeptins A1 and A2.	5.06968e-12
NC_020990.1|WP_015507351.1|2723287_2725867_-|protein-kinase/lanthionine-synthetase-C-family-protein	gnl|CDD|271199	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases. Some members of this subgroup lack the zinc binding site and the active site residues, and therefore are most likely inactive. The function of this domain is unknown.	1.44108e-92
NC_020990.1|WP_003950012.1|2727909_2729007_-|iron-ABC-transporter-permease	gnl|CDD|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	1.75294e-70
NC_020990.1|WP_003950014.1|2726084_2727062_-|iron-siderophore-ABC-transporter-substrate-binding-protein	gnl|CDD|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	3.55483e-73
NC_020990.1|WP_015507348.1|2712854_2714333_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.23737e-18
NC_020990.1|WP_015507354.1|2732125_2733190_+|YihY/virulence-factor-BrkB-family-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	3.13776e-50

Protein sequences

>NC_020990.1|WP_051085198.1|2717795_2718500_+|response-regulator-transcription-factor
MIHSSGVLRSALVALLERERFQVTGASGFSRASSTGAPGTPGAPATVTVVDGSCPVGAAHLERRSLQGSAKEPTHATPALAAARPGLGLAGAGAERAGIGLAGASRGRAALVVLAGAEHPGVLRLAYAAGALGLVDRDGPANHLATAIRLAAGGGRYVDDGLAMSLLRAMDMPLSPREVRVLSRAAQGDSVAEIARGLCLSHGTVRNYIASATRKVGARNRVDAIRISRAAGWV
>NC_020990.1|WP_003950020.1|2717235_2717487_+|hypothetical-protein
MSDTTQQTPAPGDRLVKTGGIVFIIGALATLVTVAPLFLGSDPFPTAAYLVSMLMGVGFLIAGAGLVRQIAAQRRETRAAVEG
>NC_020990.1|WP_003950021.1|2716710_2717094_-|cold-shock-protein
MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPAGVEALKPGQRVEFGVVAGQRGDQALSVVLLDPAPSVAAAQRRKPDELASIVQDLTTVLENVSRSLERGRYPDRASGAKVAGMLRAVADQLDV
>NC_020990.1|WP_003950022.1|2715700_2716594_+|1,4-dihydroxy-6-naphthoate-synthase
MSESGTGGVQGTADEAGRLSIAYSPCPNDTFVFDAVAHGRVPGAPALDVTFADIDLTNGMAERGAYDVLKVSYAALPWLLDEYALLPCGGALGRGCGPLVLTREASLPGALAGRTVAVPSERSTAYLLFRLWAADQVPGGVGEIVVMPFHEIMPAVRDGKVDAGLVIHEARFTYQNYGLHKLADMGEHWEATTGLPIPLGAIIARRSLGAERLTALAQALRTSVRMAWDDPAASRPYVLAHAQEMDADVADQHIGLYVNEFTADLGEDGYAAVRGLLTRAAAEGLVPPLAPDALRFP
>NC_020990.1|WP_015507349.1|2714907_2715633_+|futalosine-hydrolase
MRLLVATAVPPERDAVARAFGAPDTPEETALPGAVLLRTPGADVLAAGVGPAAAASATSAALTAARLAGNPYDLVVSAGIGGGFAERAPVGAVVVADRILAADLGAETPDGFVPVTGLGFGTDAHVPPAALVEAAREAGLVPGAVLTVSTVTGSADRTAELLARHPSAVAEAMEGFGVAEAAAAHGVPVLEIRAISNAIGPRDRDAWRIPAALTALTSAFVRLAPAEAGSPFALARARLVP
>NC_020990.1|WP_008415563.1|2714362_2714887_+|hypothetical-protein
MTSLPRGGAARQFSPATRRGFAVLGAVSAGLLVLSACDKPTAVATVTIGSDSVNSEATCWNGGSKIDEKKLQQCLQDKGEGDSGDGAEVKTVKVDTEADVHIGVDPKIADKGWTILMNGQPLTDASNKTFRTIPGSVFFNQQYGASGDSTVLSILENDGSSATGLWSFKLEKES
>NC_020990.1|WP_015507348.1|2712854_2714333_+|MFS-transporter
MRRAARVVGRALRTPVTGPARGIRKVTHAQGAGESGLGRLIELHGVNGAGDVMITVALASTVFFSVPTDEARGRVALYLAVTMLPFTLLAPVVGPLLDRLPHGRRAAMAGSMLARAVLALVLSGAVATGSLEMYPAALGVLVASKAYGVVRSAVVPRLLPQGFSLVKANSRVTLGGLLATGVAAPVGAGLQMIGPGWPLYGACLLFLGGAFLSFRLPPKVDSARGERRALLAADEQHLAAAVDARWDPVTTDDKTDDKTDDKTDSTDNKEEEKDRDGERGDGERGKGKERRRKGPGLRTVGPAVTHALAANACVRCQSGFLIFFLAFLLREHPLTGQSAAVSLAVVGVAAGAGNALGTAVGAWLRARAPEVIIVTVVGALVAVAVSAAVFFGAAVVAVLGAVAGFTQALAKLSLDALIQRDVPELVRTSAFARSETLLQMAWVVGGAIGIALPLRGPLGLSVGALIVALGWLTTVRALLASARRGASHPRVA
>NC_020990.1|WP_015507347.1|2711582_2712443_-|DUF3027-domain-containing-protein
MSAATTRSRTPDRLCAEAVDLARSMAEETAAPGVVGEHLAVTADGDRVATHYFACHDPGYRGWRWAVTVARASRAKYVTVDESVLLPGPDALLAPEWVPWSERLRPGDLGPGDLLPTEADDLRLEPGWIADEEPPPNSAVSADMAELVEAEDASLSAGPPADLPLAPERGSVASVAEELGLRRSRVLSRYGLLDAAERWEAQFGAESAMAQAAPAPCVSCGFLLPLAGSLRQAFGICANAYSPADGHVVSLAYGCGGHSEAAVMPTPPRPPDPALDETRLDPLPLD
>NC_020990.1|WP_003950027.1|2707191_2710425_-|hypothetical-protein
MTHPTPAQEGKDPFGTARRRRTVLDSWAASPARFREDANAEEDLALGGYRDRLIVELAQNAADAASRAGTDGRLRLTLHESAGTHVLAAANTGAPLDATGVESLSTLRASAKRPATGTATGAAPGAGPSVGRFGVGFAAVLAVSDEPAVLSRTGGVRWDLAQAREAAREVARHSPGLGDELIRRDDHVPLLRLPFPAEGIPPEGYDTVVVLPLRDAAAQDLAERLLAGVDDALLLALPGLTEIVVETPESTRVLRRRDEEPYVVIEESTGGSGATGAGATGTPAETRRWRTATSGGPLDAPLLADRPVEERLRPYWSVVWAVPVDAEGAPVRPATAPVVHAPTPSDEPLGVPALLIASFPLDTARRHVAPGPLTDFLVGRAAEAYAGLLGAWRPVGPAAVGLVPGPLGLAAVDGAVRAAVLDLLPRTAFLPPALPPAGPDEEPDTDVPLLRADRPEALRPIEAELVEGAGEATVRVLAEVLPTLLPAGLERRAELRTLGVGRLSLGEAIDRLAGVERSPAWWYRLYDSLAGVDPDRLQGLPVPLAAGSTAGSPRQVLLPGPAEDGPRPAALARLGLKVAHPEAAHPLLEKLGALPATPRAVLRTPQVRAAVAESLEGDGYALRDDAPDAEELAELVLTLARDAELAPGDEPWLGALALPDEDGELSPAGELVLPGGEFASVMREGALAAVDEEWAGRWGEQPLAACGVLARFTLVRATDVVLDPDELEPRDTDFAEPDDVGLLDAVDVWCEDVLDQLPDGPVPPVATEITAVRDLDLVDDDRWPEALALLSRPPLRDALTQPVRVLLPDGTTESVRPYTAWWLRGHPVLDGRRPAGLRAASGDALLAGLYDEVDAAGFDDALVLRALGVRTTAAALLDEPGGAAELLDRLADPDREVSARQLHALYGLLAELDPEEVTLPDELPAVADGVVTVVDARDALVADAPDLLPFAAGRPLLPVAPALAARLAELLQVGRLSEAVRVTPAGEGVEYPVPEAVRELLGDGVPASYREHDELLADGVELDWHLTASGVLHAATLEGVAAGLAWGAGQWPRRFEVAALLEDPSRRAELSRDRWFD
>NC_020990.1|WP_003950028.1|2704943_2706203_+|cytochrome-P450
MPSSAPPEQEPLVLDPTGADPHAEHRALHARGPATRVDVLGVPAWSVSDPALLRALLTSPDVSKDGRAHWPAFAETVQSWPLALWVAVRNMFTSYGADHRRLRRIIAPAFSARRVEAVRPVVERITAGLLDDLAALPPDAPVDLREKLAYPLPVAVIGHLMGVPEERYAHFRAVVDGVFDTTLGREEAAANTDALYVVLDELIATRRAEPGDDLTPLLLATPDEEGAEPALSHEELRDTLLLVISAGYETTVHVIDQAVHALLTVDGQLDLVRSGQVGWGDVVEETLRHESAVKHLPLRYAVRDIPLPDGRTIARGEAILASYAAANRHPGWHDDADVFDAGRLSKEHLAFGHGVHFCVGAPLARLEVEVCLRLLFARFPGLALDLPAEGLPPFPSLISNGHRNLPVWLHGGALGEGPG
>NC_020990.1|WP_003950018.1|2719084_2721016_-|ABC-transporter-ATP-binding-protein
MTRPRHTDGAPSPLLRPALTFARRRKGPLGALGAWSLLESARTFLTGYAVARALDDGFLAGDVRAGLLWLLALAAAALAGGFADAGVFRALGGVIEPLRDSLVRRVVRATLTRAVASPTPADTARVSRLTAQTEIARDAAGGVLLTVRSFLFTSAGAFTGLAALSPRLLPLVLIPLAAGLALFAATLRPMAARQRDLLDADEHLAAFAGRTDHAARDIAATGAAPLVTAEAAPLITAEATAASALARWSAVRVTALGLAAHLPVATLLLAAPTLLSTGLTPGELLAALTYVTTALLPAVNALLTALGAAGSRLLVVLHRLLGEEADAADVREEQAHALRADDGPRAPGAWSKGKADDEVPAIPVPSLPPEPVHGPEPFHAEPSPPGPRPTRGPRPTRPALPAATLRGLTFAYGPDAAPVLDHLDLTVEPGEHLLVVGPSGAGKSTLLALLAGTAHPRHGQIHLAGHTARHARTLGTAARVLVPQEPYIFEAPLHDNLTYLAPNAPAPRITEAIDTFTLAPLAADPARPLRPDHLTPSERRRIALARAWLTPTPLLLLDEPTAHLDAGARAATELAFASHPATVITVSHHFPAPEPGQRVLLLDGATPYLGTHASLLRESALYGELAAGLGEPSAMGSRGTAST
>NC_020990.1|WP_008415575.1|2721012_2722908_-|ABC-transporter-ATP-binding-protein
MTAAPADAARARATPAPPPAEGRLLREAVRRGRGPAALVLAATALGAAAAVTLPLALGRAVDLLIARADAGSWVLLCTALIATEVATDALVARTGGRTGAATTAWLRRRALAGFLAAPPAATTGTGLPTRLTANALDAGTAPVAAATAAAAGLAPLGGLAGLFLVDPWAGAAFVCGVPLLLLILRALLRDGRAALTTYQEEQGRMARLLTGALSGAATIAAAGTVRAEERRVLAPLAGMRAAGERTWRVQGRAAGLSGALMPLLVAAVLAVGGVRLVAGHLTPGDLLALSRYAVLAAGAGALAGAVNGWVRAKAGTARVETVTALPPTPHGTRDLPPHGDGTLALHGVHVTRDGVPLLDSVTLTLPGGTTTALVGPSGSGKSLLAAVAGRLTDPDQGTVLLDGTDLRTLSADTLRHAVAYAFERPALYGATIADAVACGPLPEPDLRRALRRAAADTFTDRLPQGPRTPLPEAPLSGGELQRLGLARAFSRPTRLLILDDATSSLDTVTAHLVARALTDTPGTRLTITHRLTTAAQSDQVVWLDGGRIRGTGPHSVLWRDPAYRAVFGAGAGGDAGAGADTVTDTEARRRSDVRTDVTGDVRTELPTDMRTDLHTGIRTDPRVDTGTGAAE
>NC_020990.1|WP_008415578.1|2723066_2723198_-|SapB/AmfS-family-lantipeptide
MALLDLQAMDTPQEEAVGDLATGSQISLLICEYSSLSVTLCTP
>NC_020990.1|WP_015507351.1|2723287_2725867_-|protein-kinase/lanthionine-synthetase-C-family-protein
MNPEYALYSGTDRWFYDTPRRAGRAADGSGNGSDGHRYALARRPAPEGWESAERGDWFSLAPAGRQLPAQGWKIHVSATPDNAEEVLETVAGICQERATAFKFLAGPALLLHRNTKYADRAGSGKFVTVYPATTAACGELAAELADALKGSAGPVVLSDLRWGEGPVHVRYGAFAPRFTRAADGSLVPAVADPAGRLVPDTRGPAFRLPDWVELPDFLRPHAEARAAQGTTDLPYTVERALHFSNGGGVYAGSHRETGEAVVLKEGRPHAGLAADGADAVTRLQREYAALRALEGLACVPRVHGLHTVGEHRFLAMEFIPGTPLNTVFARRFPLSAAEPAAEALAEHTAWALRTHQLVTEAVEALHARGIAFGDLHMNNIMVAPDQLSVTLLDFEAATPAAERRPQIVANPAFVAPPHLRGTEVDRYALACLRLALFVPLTTLLPLDRDKAAHLAGLAADRYGIDRALFDEAVTELAGPARPEAGPSRGRPPVSATDWPAARDSMVAALLASATPGRDDRYFPGDIAQFATPAGGQSYGYGAAGVLHALHAVGARCEEAEEWLIRTTRRPASGTPTGFYDGLTGIAWTLDRLGHREEALRLAHLVAAEPLDALGPGLHSGAPGVALALRDLADAADDPALGQAADRAEAAALRPAAPGGKAGLLHGPAGTALLCLRRHARTGEPALLDTAATALREELGRCVPGPDGSLVVSEARRTMPYLGSGSAGIAMVLDDYLAHRPDPAFEEARTALLRATGSAFYIQPGLFRGVAGLLLHLARTTTPGDRAARTALLTRQTALLDWHALTYQGHLAHPGEQLTRLSMDLSTGTAGVLLALAATHGEPAAHLPFLPPLRRPTDRP
>NC_020990.1|WP_003950014.1|2726084_2727062_-|iron-siderophore-ABC-transporter-substrate-binding-protein
MTRRTARPLLAATGALALAVTLTACGSGEETAADAGKDAGATRTVETAMGEVEVPEAPKRVVVLDTAELDSALTLGVKPVGAVRSDAAGGFASYLPEKELAGIENVGVIAQPNLEAIAALKPDLILTSKVRDEARYAQLSKIAATVMTENTGYPWKENFQVHAEALGKQKEADRATAAYEKRTAEVTEAVGGPAEAEKTEVNVVRFVEGADIRIYGRKNYIGTLLADVGLGRPAITDKATDGFSYDVSPEKIDLADADVVFTATYGDPEKAKETQTTSSALWRSLDAVKSGAVHKVEDELWIQGIGYTAAQQILDELEEALTSAS
>NC_020990.1|WP_003950013.1|2727058_2727913_-|ABC-transporter-ATP-binding-protein
MTRPAARLTARDLTLAYEDRTVVPGLDLDIPDGRVTVIIGPNACGKSTTLRALGRLLRPAGGAVLLDGAELARLPTRQIARQIGLLPQTPVAPEAITVADLVARGRQPHQRWWQQWSEEDERAVTEAMARTATTDLADRPVDALSGGQRQRVWIAMALAQETGLLLLDEPTTYLDLAHQVEVLDLVRRLNREQGRTVVLVLHDLNQAARYADHLIAFREGRVVAEGAPAEVVTAGLVREIFGLECVVVPDPVTGSPLVVPGAPWDARPAPEPAVPTREESRATP
>NC_020990.1|WP_003950012.1|2727909_2729007_-|iron-ABC-transporter-permease
MSGGSVVLKAGPEPARVRPAGYVPVRVGPASLLVPVRAVATGAVLAGVLAVVCVAYLSVGESFVAPGSVVDVLLGRPSPDTLVVGELRLPRMVAGLYVGAAFGIAGALIQTVARNPLASPDLIGVSQGASAATVAALTFGVTSYTVLPWISVGGGLLAALLVHLFAWRGGLQATRFVLVGVGFAVALRALTTLFLTKGDQTVAQQAQVWMSGSLNGRAWPEAALVGWTLLAALPALVWAARAQRTVTLDDATATSLGARLGRARLGLVLVGVVLASVATGAAGPVDFVALLAPQIARRLARTAQIPLVCSALAGAVTVVAADLLARRLFAPTELPVGVLTAAVGAPYLIWLLVTRHGPRATGGTS
>NC_020990.1|WP_015507352.1|2729003_2730068_-|iron-ABC-transporter-permease
MPPAPPAAPSPAKAPPTAPRPRRDGAVRRAVWTVAALVALLVAVVLSLAVGARTVAPGTVVEALFQGATGPDAEVVREMRLPRTLIGVMVGAALAVAGTALQGITRNPIADPGILGISQGASVGVVLAIAFAGVHTLAGYVWFAFVGAGLAAVAVYAVAAGGRGGATPVKLALSGAAINALLVSVTTAVLTTSSSALDEFRFWNVGALQGRGADVAVQVWPFLLVGLALVASSARGLDALALGEDVAKGLGQRVAAVRITAGAGAAVLTGVGVAAAGPVAFVGLAVPHLVRHLVGGDHRWVLPLAALTGPVMLLASDTVGRVLFPPGEVPAGVMTALIGVPFLVALVRSRAVTA
>NC_020990.1|WP_015507353.1|2730200_2730887_+|HAD-family-hydrolase
MPEHLTSAAAPAPSDPAVPAARPVPGGAGPVVGFDLDMTLIDSRPGIGAAYRVLAAETGVPIDVDLVVSRLGPPLETELACWFPAEQVPAAAARYREVYPTTAIAPSLALPGAAAALEAVRAHGGRSLVVTAKNEEHARLHLDHLGLRADLVVGSLWAEAKGGALRAQGATVYVGDHVGDVRGARAAGAFSVAVVTGGCTPDELRTAGADLVLPDLTAFPAWLAEFAR
>NC_020990.1|WP_015507354.1|2732125_2733190_+|YihY/virulence-factor-BrkB-family-protein
MKQPARTAGGAVAEEARTVEGAEGDGPVKGEPGRTVEWWVALRRTPGAFWRDDVSDFAAALTYYAILAVLPALLVVVIAFGLVSPDTAERFVGQVTAWAPGGSGASLREVLTRVVRVDSTAWTLLVTGGASALWSASSYLAVSRRALHRMYGVRDRRSPWGKAHRIVATALALLALLLVSSLLLMLTEPVAESIGRLLGLDAGVAWAWSVLRWPLLLCLVACLVVVVFRNGPVAARRRAHSIPGGALAATLWLTASAGLALYASVLSTYSRLYGSLAGIVVFLVWLWLSNVALLLGAQFTAELCRAAGGPGAPACHPEPAEEVAAQDASAGAEDPEDTEDTEETREHGRAPTGA

Crispr_ID: NC_020990_14

• CRISPR_ID: NC_020990_14
• CRISPR_location: 2786763-2786884
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_14

Consensus_repeat	Method
AAAGATGGCCTCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NC_020990_14

>14.1|2786791|66|NC_020990|CRISPRCasFinder
CGAAAGATGGCCTCAAGCGCCGGCCGGGCTGATCTTTGACGGGCCGTCCGCTCACAGGCGCGCGCC

CRISPR arrays and Neighbor proteins around NC_020990_14

CRISPR arrays

The CRISPR arrays of NC_020990_14

>merge|NC_020990|14|2786763-2786884|CRISPRCasFinder
TGGGGTGGCCTCAAACGCCGGCCGGGCTCGAAAGATGGCCTCAAGCGCCGGCCGGGCTGATCTTTGACGGGCCGTCCGCTCACAGGCGCGCGCCAAAGACGGCCTCAAGCGCCGGCCGGGCT

>NC_020990|14|12|2786763-2786884|CRISPRCasFinder
TGGGGTGGCCTCAAACGCCGGCCGGGCT	CGAAAGATGGCCTCAAGCGCCGGCCGGGCTGATCTTTGACGGGCCGTCCGCTCACAGGCGCGCGCC
AAAGACGGCCTCAAGCGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003949950.1|2793511_2793829_-|DUF3263-domain-containing-protein	unknown	unknown	gnl|CDD|378688
NC_020990.1|WP_008411317.1|2783253_2783517_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507370.1|2782148_2782616_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507374.1|2793873_2795211_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270452
NC_020990.1|WP_003949964.1|2778918_2780532_+|PTS-transporter-subunit-EIIC	unknown	unknown	gnl|CDD|181971
NC_020990.1|WP_015507372.1|2783964_2784450_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949965.1|2777908_2778874_+|N-acetylmuramic-acid-6-phosphate-etherase	unknown	unknown	gnl|CDD|235467
NC_020990.1|WP_015507373.1|2792598_2793456_-|trehalose-phosphatase	unknown	unknown	gnl|CDD|319767
NC_020990.1|WP_003949955.1|2787741_2788020_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340594
NC_020990.1|WP_015507375.1|2796636_2796969_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949957.1|2784830_2786453_-|chaperonin-GroEL	unknown	unknown	gnl|CDD|234573
NC_020990.1|WP_008411314.1|2783513_2783756_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949956.1|2787093_2787297_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NC_020990.1|WP_003949962.1|2781565_2782084_+|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	unknown	unknown	gnl|CDD|319968
NC_020990.1|WP_015507369.1|2780609_2781509_+|oxidoreductase	unknown	unknown	gnl|CDD|236676
NC_020990.1|WP_003949961.1|2782612_2783209_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NC_020990.1|WP_003949948.1|2795588_2796512_+|SIS-domain-containing-protein	unknown	unknown	gnl|CDD|225132
NC_020990.1|WP_003949953.1|2789893_2790913_+|glucosyl-3-phosphoglycerate-synthase	unknown	unknown	gnl|CDD|237556
NC_020990.1|WP_003949952.1|2791116_2792568_+|trehalose-6-phosphate-synthase	unknown	unknown	gnl|CDD|340820
NC_020990.1|WP_030770559.1|2788100_2789408_-|threonine-synthase	unknown	unknown	gnl|CDD|236065

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_015507374.1|2793873_2795211_-|extracellular-solute-binding-protein	gnl|CDD|270452	cd14749, PBP2_XBP1_like, The periplasmic-binding component of ABC transport systems specific for xylo-oligosaccharides; possesses type 2 periplasmic binding fold. This group represents the periplasmic component of an ABC transport system XBP1 that shows preference for xylo-oligosaccharides in the order of xylotriose > xylobiose > xylotetraose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.59477e-57
NC_020990.1|WP_003949964.1|2778918_2780532_+|PTS-transporter-subunit-EIIC	gnl|CDD|181971	PRK09586, murP, PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed.	6.45424e-112
NC_020990.1|WP_003949962.1|2781565_2782084_+|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	gnl|CDD|319968	cd16361, VOC_ShValD_like, vicinal oxygen chelate (VOC) family protein similar to Streptomyces hygroscopicus ValD protein. This subfamily of vicinal oxygen chelate (VOC) family protein includes Streptomyces hygroscopicus ValD protein and similar proteins. ValD protein functions in validamycin biosynthetic pathway. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.82329e-44
NC_020990.1|WP_015507373.1|2792598_2793456_-|trehalose-phosphatase	gnl|CDD|319767	cd01627, HAD_TPP, trehalose-phosphate phosphatase similar to Escherichia coli trehalose-6-phosphate phosphatase OtsB and Saccharomyces cerevisiae trehalose-phosphatase TPS2. Trehalose biosynthesis in bacteria is known through three pathways - OtsAB, TreYZ and TreS. The OtsAB pathway, also known as the trehalose 6-phosphate synthase (TSP)/ Trehalose-6-phosphate phosphatase (TPP) pathway, is the most common route known to be involved in the stress response of Escherichia coli. It involves converting glucose-6-phosphate and UDP-glucose to form trehalose-6-phosphate (T6P), catalyzed by TPS, the product of the otsA gene, this step is followed by the dephosphorylation of T6P to yield trehalose and inorganic phosphate, catalyzed by a specific TPP, the product of otsB gene. This OtsAB (or TSP/TPP) pathway, is also the most common route known to be involved in the stress response of yeast In Saccharomyces cerevisiae, the corresponding enzymes, TPS1p and TPS2p, form a multimeric synthase complex together with additional regulatory subunits encoded by Tsl1 and Tps3. Trehalose is a common disaccharide accumulated by organisms as a reservation of carbohydrate and in response to unfavorable growth conditions. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.52193e-30
NC_020990.1|WP_003949955.1|2787741_2788020_-|MoaD/ThiS-family-protein	gnl|CDD|340594	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins. CysO, also termed 9.5 kDa culture filtrate antigen cfp10A, together with CysM (Cysteine synthase M), forms a protein complex CysM-CysO that represents a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. The replacement of the acetyl group of O-acetylserine by CysO thiocarboxylate to generate a protein-bound cysteine is catalyzed by CysM in a pyridoxal 5?-phosphate (PLP)-dependent manner. The family also includes QbsE that functions as the sulfide donor for the biosynthesis of thioquinolobactin in Pseudomonas fluorescens. A JAMM motif protein QbsD catalyzes removal of the carboxy-terminal dipeptide from QbsE. Both CysO and QbsE are similar to prokaryotic sulfur carrier proteins such as ThiS and MoaD, containing the beta-grasp ubiquitin-like fold.	3.06365e-42
NC_020990.1|WP_003949957.1|2784830_2786453_-|chaperonin-GroEL	gnl|CDD|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NC_020990.1|WP_030770559.1|2788100_2789408_-|threonine-synthase	gnl|CDD|236065	PRK07591, PRK07591, threonine synthase; Validated.	0
NC_020990.1|WP_003949956.1|2787093_2787297_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	6.0198e-35
NC_020990.1|WP_003949965.1|2777908_2778874_+|N-acetylmuramic-acid-6-phosphate-etherase	gnl|CDD|235467	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed.	1.65515e-160
NC_020990.1|WP_015507369.1|2780609_2781509_+|oxidoreductase	gnl|CDD|236676	PRK10376, PRK10376, putative oxidoreductase; Provisional.	1.14841e-94
NC_020990.1|WP_003949961.1|2782612_2783209_+|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.08445e-25
NC_020990.1|WP_003949948.1|2795588_2796512_+|SIS-domain-containing-protein	gnl|CDD|225132	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane].	6.41829e-39
NC_020990.1|WP_003949953.1|2789893_2790913_+|glucosyl-3-phosphoglycerate-synthase	gnl|CDD|237556	PRK13915, PRK13915, putative glucosyl-3-phosphoglycerate synthase; Provisional.	6.75701e-169
NC_020990.1|WP_003949952.1|2791116_2792568_+|trehalose-6-phosphate-synthase	gnl|CDD|340820	cd03788, GT20_TPS, trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.	7.67811e-143
NC_020990.1|WP_003949950.1|2793511_2793829_-|DUF3263-domain-containing-protein	gnl|CDD|378688	pfam11662, DUF3263, Protein of unknown function (DUF3263). This family of proteins with unknown function appears to be restricted to Actinobacteria.	3.59748e-31

Protein sequences

>NC_020990.1|WP_003949957.1|2784830_2786453_-|chaperonin-GroEL
MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPMALKRGIEKAVEAVSSALLEQAKDVETKEQIASTASISAADTQIGELIAEAMDKVGKEGVITVEESQTFGLELELTEGMRFDKGYISAYFATDMERMEASLDDPYILIVNSKIGNVKDLLPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLGDIAILTGGTVISEEVGLKLENAGLDLLGRARKVVITKDETTIVDGAGDSDQVNGRVAQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQASSVFEKLELEGDEATGAAAVKLALEAPLKQIAVNGGLEGGVVVEKVRNLSVGHGLNAATGEYVDMIAEGILDPAKVTRSALQNAASIAALFLTTEAVIADKPEKAAAAAPGGMPGGDMDF
>NC_020990.1|WP_015507372.1|2783964_2784450_+|hypothetical-protein
MTTTRPGTAPDGADDPYEPVFTPARGGARYVYNHRNPVGLALILLAPLTALGVILYLHDSGSWSRGELRDAVYGAAEEMNRAPHVHHSDLGYAWSLEDAVDRQPGTPFIGASVHRGTGPDRTAYTVTGSGTSAAYCLHVYEGHDAAADRSILHVLAEDGPC
>NC_020990.1|WP_008411314.1|2783513_2783756_-|hypothetical-protein
MSAVKGTEAHGRTTDRVGAAQEAVDRLRAGLAEAGIVLPSLRLEPVSSAGNDPAPLVDLGRCNVETADRLSAVLEGARQR
>NC_020990.1|WP_008411317.1|2783253_2783517_-|hypothetical-protein
MSDDDACCAGGDEPEAPEVAWVVGAFAVDARDGRLGRVMGSEGPYIQLRPPGGGKEWDCPPRAVRAADRKEVLRAKVREINWEGRLP
>NC_020990.1|WP_003949961.1|2782612_2783209_+|GNAT-family-N-acetyltransferase
MTEPDCPAPVPDAPFPCGALMRLVRPDDAPALLAAYRRNAAHLAPTEPRRGERFATLEGQRERIEGQLREWEAGRAVPWVLDGSGVPGAPPVLGTLTFTGIVRGPLLSASVGYWVDQGHTGRGLAGQALAHAVAYARDALGLHRLEAGTLLDNTASQRVLLRAGFTWYGTAPDYLHIAGAWRDHHRYQLILGEVEPRP
>NC_020990.1|WP_015507370.1|2782148_2782616_+|hypothetical-protein
MTLPPPPADTPAAHALALLGERGAGRLPHPGGDLATHLRRVHSQLATWGARPALRLAGLCHAFYGTDGFPTALLPLPSLAARRDFAEISAANELGLAAHDPDFRAAHGPDLLALFTRVSSLLSPAAWADCQAVLAGPLPGSPEGPPPPCGVPSAG
>NC_020990.1|WP_003949962.1|2781565_2782084_+|glyoxalase/bleomycin-resistance/dioxygenase-family-protein
MTVRGIDHIGLTVPDLEAATRFLADALGAEVLYDTLPAGRGPVGGPETEQRLGVPPGTRQLAIRMLALPDGPGIELFAYDPPGRSPALPHDLGWQHLALYVDDLDATLARAVEAGADPLAPPHPLPGPEAGPANRFAYLRTPWGSTLELVTYPDPQPYEEETARRRWRPARG
>NC_020990.1|WP_015507369.1|2780609_2781509_+|oxidoreductase
MTTPPPHPSALDSGTWQLADDLPAVRRVGYGSMRLPGPLDGPGTDRERALRVLRRAVELGVNHFDTAAFYFSTTRSANELINAALAPYADDLVIVTKVGPGRDTWGRWQWASPEQLRGQVEENLRQLGRDHLDVVNFRVQGQESTQSLADHFGALAELREAGLVRHLGVSNVRPHHLAEARAIAPVVCVQNLYGTGASAQEQEFVQECGEAGIAYVPFFSISGARREAGAGEPGQAVREIAEAHGATPAQVKLAWTLQQGPHVLAIPGTTDPAHLEENVAAGSLRLSEAELERLGTPVA
>NC_020990.1|WP_003949964.1|2778918_2780532_+|PTS-transporter-subunit-EIIC
MAENKNRALAAAILPLVGGAANVTTVVHCMTRLRLGLADRSLVQDEALKAVPGVMGVVEDDTYQIVLGPGTVARVTPEFEALVEEERAAAPAPRPVPASAGAPEPHPVTAEELAARGAEIKAERKARNATPLKLFLRRIANIFVPLIPALIGCGIIAGVNGLLTNLGWAPGVTPALGALASGFMALIAVFVGYNTAKEFGGTPILGGAVASIIVFPGIGDVEVFGSKLSPGQGGVLGALGAAVLAVYVERWCRRWVPEAVDVLVTPTVTVLVSGLVTVFGLMFVAGQIASGIGTGADWLLENTGAFAGFVLGGLFLPLVMLGLHQALIPIHTTLIESQGYTALLPILAMAGAGQVGCAVAVYLRLRRNASLRRTIRSAMPAGILGVGEPLIYGVSLPLGRPFITACVGGAAGGAFIGAFSMLGDTVGSTAIGPSGWALFPLLAGNQSLGLLIAVYGGGLLTGYLVGFLATYFFGFSKQMLTDLNADVDAGESGEARAEAEPTDAAPDSPEAPDAPGTPGGPRPGTPPAPAPAPAPSS
>NC_020990.1|WP_003949965.1|2777908_2778874_+|N-acetylmuramic-acid-6-phosphate-etherase
MTDTTARADVPSDGGIRAQLETLTTEAFRPELAEIDRLSTLEIARTMNAEDATVPGAVARVLPEIAAAIDRIAERMARGGRLVYAGAGTAGRLGVLDASECPPTFNTDPAEVVGLIAGGPTALVTSVEGAEDSAELAAQDLAALALTAEDTVVGISASGRTPYAVGAVEYARRAGALTVGLSCNAGSALAAAADHGIEVVVGPELLTGSTRLKSGTAQKLVLNMISTLTMIRLGKTYGNLMVDVRASNEKLRARSRRIVALATGAGDEEIEAALTATGGEVKNAILTILGGVDAPAADRLLTDARGHLREALAAARPGSTT
>NC_020990.1|WP_003949956.1|2787093_2787297_-|cold-shock-protein
MAQGTVKWFNAEKGYGFIAVDGGADVFVHYSAIQMDGYRTLEEGQRVEFEISQGQKGPQADMVRVAA
>NC_020990.1|WP_003949955.1|2787741_2788020_-|MoaD/ThiS-family-protein
MSVNVRIPTILRTYTGGRSEVPAEGATLAEVIADLEKNHSGIAARVLDDQGKLRRFVNVYVNDDDVRFEQGLETATPDGAGISIIPAVAGGC
>NC_020990.1|WP_030770559.1|2788100_2789408_-|threonine-synthase
MAVHTVATPATPSQDTSAVDLGPAVALSCRECGERFPLGPVFACVSCFGPLEVAYDLPTGDPEALRAAIEAGPANIWRYAPLLPVPADVATKPSLNPGFTQLVKADHLAAELGVTGGLYVKDDSGNPTHSFKDRVVAIAVEAARAFGFTTLSCSSTGNLAGAVGAAAARAGFRSCVFIPHDLEQGKVVMAAVYGGDLVGIEGNYDDVNRFCSELIGDPLGEGWGFVNVNLRPYYGEGSKSLAYEIAEQLGWRLPDQIVIPVASGSQLTKIDKGFKELIALGLVEDRPYKIFGAQAEGCSPVSTAYKAGHDVVRPQKPDTIAKSLAIGNPADGPYVLDIARRTGGAVEDVDDAQVVDAIKLLARTEGIFAETAGGVTVGVTRKLIEAGLIDPSLTTVVLNTGDGLKTLDAVAPTTGPTATIRPDLDAFRAAGLATS
>NC_020990.1|WP_003949953.1|2789893_2790913_+|glucosyl-3-phosphoglycerate-synthase
MLEEVERWLTKRSWSAADRPLSALVAAKRRSGSTVSVVLPALNEEATVGAIVAEIRRSLMEAVPLVDELVVIDSGSTDRTSQEAAAAGARVVHRDVILPRMPAVPGKGEVLWRSLMVTSGDIVCFVDADLKDFSPDFVSGIVGPLLTEPDVDFVKAMYDRPLGSAPGQGGRVTELMARPVLNLHWPHLAGFVQPLGGEYAVRRGLLEQLPFPVGYGVELGLLVDALHTVGLDALAQVDVGVRVHRHQDGLALGRMAAAIYRTAQLRLARGHLVRPELTQFERGDDGFVARTTKVDTEERPPMIEITEYRGGRLAGTPQEPLPEHTAHTRLPDSYHRRTG
>NC_020990.1|WP_003949952.1|2791116_2792568_+|trehalose-6-phosphate-synthase
MAVTADSARILVASNRGPVSYALLPDGELEAKRGGGGLVSGLSAIGADASTLWVCAALGDGDREAARRAGTGTLETEDTGGQRVRMLDIPADTHAAAYNGIANSVLWFVHHMLYQTPVEPAFGPEFREEWAAYEAYNRAFAQALAAEAGEGAAVLVQDYHLALVPGMLRALRPDLRIAHFTHTPWAPPDYFRLLPDDIAAQLLTGLLGADRLGFLTRRWAGAFADCAQAVLGAERAGASELAYDGRRTAVGVYGLGADAEFLRERAHRTDVDDRLVALREQIGEPDRKTIVRVDRTELSKNIVRGLLAYRQLLLDHPEWAGRVVHIAFAYPSRQDLPVYREYTASVRALADEINEQFGTVGWTPVVLHVEDDFARSLAAYRLADVALVNPIRDGMNLVAKEVPVVSDAGVALVLSREAGAYEELGEDALPVNPYDVSATARALHDALMMPPSERAERSKRLAAAATALPPQRWFLDQLEALGG
>NC_020990.1|WP_015507373.1|2792598_2793456_-|trehalose-phosphatase
MASPARPSPLPLPDTAAGREGLETLLARPAEAVVGLDFDGTLAPIVADPDRAGAHPDAVPALAALAPLVRSVAVITGRPAEKAVLLGGFADEPGLGHLTVLGHYGAQRWDAATGELHTPETPPGLAAARAELPAVLADAGDPPGIWTEDKGQAFAVHTRRAEDPEGAFASLRGPLAALTERHGLHLEPGRLVLEIRPPGVDKGVALIDYVQETDARAVLYAGDDLGDLAAYDAVDRLRGEGVPGLLVCSGDEVPELASRADLVVPGPGQVAALLAAIAETIRRAR
>NC_020990.1|WP_003949950.1|2793511_2793829_-|DUF3263-domain-containing-protein
MTDHEPASPEAATPQEPDSADGSGDLGDGIGDGLSEQDRAVLALEARGWQRPGTKERAIREQLGLSPTRYYQLLGALLDDPAALRHDPVTVNRLRERRAARRAAR
>NC_020990.1|WP_015507374.1|2793873_2795211_-|extracellular-solute-binding-protein
MRRHHEGRGEGRGDRRGRGAARSATALAVVLALAAALAGCGSDSAEESADEEVALRLVAPEYGDSAKTSSKGYWKRVVASFEKGHPGTTVDVEVHPWRTVDKVLARQVAAGDAPDLAISGTYASYAADGRLYRADDLLSIGTQADFLPPLARAGEMQRVQYGMPFAASTRLLFYNRDLFEEAGLTPPKTWDGVRGAAEALKKRDVPYPYALPLGPEEAQAETLNWLLSGGSGYTDDLGSYTLDSPENVETVGWLKKELVGEGLTGPTPPGELDRADAYAAFAKGRVGMVNGHPSLMRAAERSGVRYGVAPVPGRTEDAGATLGVTDWMIGFRQAGHPEEAGAFLDHVYSEKNVLAFTRAHDLLPVTHTASDTLTAAPGNTTLRRFLAELPEARLYPSEKTSWPELSTRIKSGLADAVAPGGSPEAVLSRLQRHAAAYENPQAGNG
>NC_020990.1|WP_003949948.1|2795588_2796512_+|SIS-domain-containing-protein
MSRTAAEITTQPACWRRAAEEAARFTAAPRPGERVAVVGCGTSWFMAQSYAALREGAGQGATDAFAASEFPRARAVGAYDRVVALTRSGTTTEVLELLALVRAAGTATVALTADPATPVMTAADEVAVLDWADEESVVQTRFATTALAFLRATLGDLPGLASVPRAADDAEHAVTEPLPRPLLTAGQWTFLGRGWAYGLAQEAALKMREAAGAWTESYPAMEYRHGPIAITAPGRVTWLFGEAPAGLADDVHRVGGHFEHHPTTDPLADLIRAQRLAVALAEAQGHNPDRPRNLTRSVVLATDDSRH
>NC_020990.1|WP_015507375.1|2796636_2796969_+|hypothetical-protein
MPYSFLLRLLPTETPPHLYRATVHNADGTQEAFLLLTPDPPSVHLADARGNPSGGLRMSLADGTVERTDAEPQEAHPALTTEDFMTVAAHLLTQHRRQGRPPGEVCKVFA

Crispr_ID: NC_020990_15

• CRISPR_ID: NC_020990_15
• CRISPR_location: 2871377-2871558
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_020990_15

Consensus_repeat	Method
GCCGGTCACCGATGGCCTCAAACGCCGGCCGGGCTGAGGTGG	PILER-CR

spacers of NC_020990_15

>15.1|2871420|21|NC_020990|PILER-CR
GGTGACGCTCGGCCCCACCGC
>15.2|2871484|47|NC_020990|PILER-CR
ACCGCGATGGAGGCAGGGCTCCGCCTCCATCTGCCCGCCCCGACCCT

CRISPR arrays and Neighbor proteins around NC_020990_15

CRISPR arrays

The CRISPR arrays of NC_020990_15

>merge|NC_020990|15|2871377-2871558|PILER-CR
GGCCTCAAACGCCGGCCGGGCTGAAGTGTGGTGACGCTCGGCCCCACCGCGCCGGTCACTGATCGGCCTCAAACGCCGGCCGGGCTTGGGTGGACCGCGATGGAGGCAGGGCTCCGCCTCCATCTGCCCGCCCCGACCCTGCGGGTCACCGATGGCCTCAAGCGCCGGCCGGGCTGAGATCG

>NC_020990|15|5|2871377-2871558|PILER-CR
GGCCTCAAACGCCGGCCGGGCTGAAGTGTGGTGACGCTCGGCC	CCACCGCGCCGGTCACTGATC
GGCCTCAAACGCCGGCCGGGCTTGGGTGGACCGCGATGGAGGC	AGGGCTCCGCCTCCATCTGCCCGCCCCGACCCTGCGGGTCACCGATG
GCCTCAAGCGCCGGCCGGGCTGAGATCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_015507393.1|2861934_2862843_-|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176231
NC_020990.1|WP_003949859.1|2871797_2872583_-|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238870
NC_020990.1|WP_003949855.1|2877480_2877684_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NC_020990.1|WP_030307725.1|2878269_2878614_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133394
NC_020990.1|WP_003949857.1|2875030_2875342_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949863.1|2866797_2867718_+|diiron-oxygenase	unknown	unknown	gnl|CDD|378680
NC_020990.1|WP_003949865.1|2865389_2865941_-|CrcB-family-protein	unknown	unknown	gnl|CDD|376809
NC_020990.1|WP_003949864.1|2865984_2866623_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507394.1|2863092_2864367_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NC_020990.1|WP_003949850.1|2880612_2881674_-|cobalamin-binding-protein	unknown	unknown	gnl|CDD|227345
NC_020990.1|WP_003949856.1|2875520_2877032_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NC_020990.1|WP_003949870.1|2860957_2861905_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378976
NC_020990.1|WP_015507396.1|2869789_2871058_+|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl|CDD|234960
NC_020990.1|WP_003949858.1|2873973_2874936_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223566
NC_020990.1|WP_003949866.1|2865015_2865393_-|fluoride-efflux-transporter-CrcB	unknown	unknown	gnl|CDD|223317
NC_020990.1|WP_015507395.1|2867860_2869573_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|215457
NC_020990.1|WP_008409854.1|2878641_2879181_-|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NC_020990.1|WP_003949852.1|2879308_2879659_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_020990.1|WP_003949851.1|2880182_2880566_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_020990.1|WP_003949867.1|2864363_2864999_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_015507393.1|2861934_2862843_-|zinc-binding-dehydrogenase	gnl|CDD|176231	cd08270, MDR4, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.58522e-103
NC_020990.1|WP_003949859.1|2871797_2872583_-|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	3.45268e-61
NC_020990.1|WP_030307725.1|2878269_2878614_+|MerR-family-transcriptional-regulator	gnl|CDD|133394	cd04766, HTH_HspR, Helix-Turn-Helix DNA binding domain of the HspR transcription regulator. Helix-turn-helix (HTH) transcription regulator HspR, N-terminal domain. Heat shock protein regulators (HspR) have been shown to regulate expression of specific regulons in response to high temperature or high osmolarity in Streptomyces and Helicobacter, respectively. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	7.07293e-09
NC_020990.1|WP_003949863.1|2866797_2867718_+|diiron-oxygenase	gnl|CDD|378680	pfam11583, AurF, P-aminobenzoate N-oxygenase AurF. This family is a metalloenzyme which is involved in the biosynthesis of antibiotic aureothin by catalyzing the formation of p-nitrobenzoic acid from p-aminobenzoic acid. AurF is a non-heme di-iron monooxygenase which creates nitroarenes via the sequential oxidation of aminoarenes.	5.73174e-103
NC_020990.1|WP_003949865.1|2865389_2865941_-|CrcB-family-protein	gnl|CDD|376809	pfam02537, CRCB, CrcB-like protein, Camphor Resistance (CrcB). CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.	7.40028e-33
NC_020990.1|WP_003949855.1|2877480_2877684_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	3.10682e-34
NC_020990.1|WP_015507394.1|2863092_2864367_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.62102e-52
NC_020990.1|WP_003949850.1|2880612_2881674_-|cobalamin-binding-protein	gnl|CDD|227345	COG5012, COG5012, Predicted cobalamin binding protein [General function prediction only].	7.02863e-19
NC_020990.1|WP_003949856.1|2875520_2877032_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	1.35115e-118
NC_020990.1|WP_003949870.1|2860957_2861905_-|AraC-family-transcriptional-regulator	gnl|CDD|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	1.98068e-31
NC_020990.1|WP_015507396.1|2869789_2871058_+|tRNA-4-thiouridine(8)-synthase-ThiI	gnl|CDD|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	5.17378e-167
NC_020990.1|WP_003949858.1|2873973_2874936_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	1.08563e-41
NC_020990.1|WP_003949866.1|2865015_2865393_-|fluoride-efflux-transporter-CrcB	gnl|CDD|223317	COG0239, CrcB, Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning].	6.43239e-31
NC_020990.1|WP_015507395.1|2867860_2869573_+|FAD-dependent-oxidoreductase	gnl|CDD|215457	PLN02852, PLN02852, ferredoxin-NADP+ reductase.	2.30819e-118
NC_020990.1|WP_008409854.1|2878641_2879181_-|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	3.3871e-15
NC_020990.1|WP_003949852.1|2879308_2879659_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	2.3583e-20
NC_020990.1|WP_003949851.1|2880182_2880566_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	4.95743e-15
NC_020990.1|WP_003949867.1|2864363_2864999_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.64385e-68

Protein sequences

>NC_020990.1|WP_015507396.1|2869789_2871058_+|tRNA-4-thiouridine(8)-synthase-ThiI
MNAVVPAQGVPDLAGPVPIGPCVLLKHGEVFLKGRNRHLFVERLHDNLRGALRGVTGSIWIKEMQNVTVLGGDAPQDELIARARRVMGFVAVQPAMRVETGEEAIVAAAVAALDGAAPGTTFAVRARRRHKPFPLTSTQLERLVGARIQEAHGLPVDLTRPDIRVEVEIDRKESYVSGLRHTGQGGLPVGTSGRALVLLSGGYDSPVAAHRAMRRGLRCDFVHFTGAPYTNAASAFKAYALARELNRYQPPGKLHIVALGHAQKQLAVVGAGRFQVVGQRRLMVKAASVLARRLRAQALVTGDALGQVASQTLSNMALVDEAATLPVLRPLIGWEKQEIIDEARRVGTAEISVLPDEDCCQLLAPRQVSLRTKLEDVAGFEKRLDADELIDQMLASAQVTRPGTDETPAPATPPAASACGTD
>NC_020990.1|WP_015507395.1|2867860_2869573_+|FAD-dependent-oxidoreductase
MTYAITQTCCNDATCVAVCPVNCIHPTPEERAFGSTEMLHIDPRSCIDCGACADACPVDAIFPVDRLKPAHREYAALNAAYYEEEATTTEREEAAAAPASVTGDGAEAQAEAAERTGPLFRAWDAPGFARSLPSDFAPLRIAVVGTGPAGMYAAEDLLLHTDAQVTLVDRLPVAGGLIRYGVAPDHPATKKVGEAFARFHHHPRVRMQLGLEVGKELSAAELAAHHDAVIYAVGAATDRRLGIPGEELPGSVSATGLVAWYNAHPDHAPDAVSLDAERVVVVGNGNVALDVARILVSDPDTLAATDIAGHALDALRGRRVREVVLLGRRGPEDAAYTRTELLALGHLDGVDLVVDDHDPRIGAAIDAAGPLDKAGMLGGVTRTAVDWSRPPEPGRRIVFRFHSAPLAVTGEQAVTGVQVTGGTEIPAQLVVRSIGHRGVAVPGLPFDETTGTVPHEGGRVRGRSNEYVVGWIKRGPSGGIGANRSCAAETVTTLLADAVAGELPTPSGSAKEFARLARRRNRRLVDARGLAAIERAERESGRRDGRVRTKFATVPELVAAARRSRLRLPG
>NC_020990.1|WP_003949863.1|2866797_2867718_+|diiron-oxygenase
MATTDAQPAAQDEGGHDINDITRRLLESSAKLSYDPATEVDWDTPLDKSFHGMSPEWSSLYGTRYWDELTEDQRKELTRQESGSVASTGIWFEVILQQMVLRDIYAKDPGSPEFQWALTEIADECRHSIMFARGVRKLGAPAYKPRRAVMELGRLFKTLAVGEAAYASILVAEEVLDVMQRDWMRDERVVPFVRTINNIHVVEESRHMKFARDETIKRLEKAGWLRRNVQALVISICAYFVITSMWNRDVYRNAGLNTERALAEAKANQHHKSMIRSSCSGLMDFLASAKLLTRPAAAVYRRANLL
>NC_020990.1|WP_003949864.1|2865984_2866623_+|hypothetical-protein
MRPPAAPAPADPPGPGPEPEPAWNVALRRLLGDPYVFVATGPRRHEEWARDVLAVLRREVADPRGRPGLDADRTGPGRDAVPAYPFAPPPAERFPAYLRPLERAAAVGALAVMSEEWQFEPAPVRSRPDREAVLADARTLLDRYGPDAEYWTNAVAAGSGPAPDFVAAGLRGTASYTFLTGAYVNGLDLCDDLGLIAVSADEVGVFWSVGAC
>NC_020990.1|WP_003949865.1|2865389_2865941_-|CrcB-family-protein
MSHPPHTPDGAAPDPAESHRANLPLPPPEPVDPDLGPELAPGERPESQAPVLLAIALGGGLGAVIRYGATVLWPTPAGSFPWTILVVNVVGCAAMGVLMALLTEVWPDAPRLTRPFLGTGVLGGFTTFSTYAVDVQTLFDGGSPARALGTLVLTVAAALAAVAGASWLTRSAVRLGRAEGSLA
>NC_020990.1|WP_003949866.1|2865015_2865393_-|fluoride-efflux-transporter-CrcB
MTWLLVVVGGMIGAPCRYLMDRAVQRRHSSGFPWGTLAVNMSGSLVLGVLVGARLTGAAPENLMVFAATGFCGAYTTYSTFSYETLRLAETGARGAAFANVALSVSAALGAAVMGLGVAKAVWGG
>NC_020990.1|WP_003949867.1|2864363_2864999_+|response-regulator-transcription-factor
MTVIRLLLADDHPIVRAGLRAVLETEPDFEIAGEAASAEEAVALAGRLAVDVVLMDLQFGPGARMNGSEATAAITARPGAPRVLVVTTYDSDADTLPAIEAGATGYLLKDAPPEELAEAVRTAAAGRTTLAPAVADRLLRRMRTPGTALSRRETEVLGLVAEGMSNLRISERLHLSQATVKSHLVHIYAKLGVDSRTAAVAAALERGLIRR
>NC_020990.1|WP_015507394.1|2863092_2864367_+|sensor-histidine-kinase
MPSTTPAPAPPRAPLSTPAPRVLAWCLHLLVAALLVMAVGRALVDGGGQGWAVVVAGVAFGAVYAAGPVVPGVRGSRRGAVVWLVAVGVLWAGLLGLTADAMWLAFPLFFVQLHLLAGRAGPWAVALTTGVAVCSYAAHQGGFTAAAAIGPVIGAAVAVAVVRGYQALYRESEQRRRLIEELTRARADLAAAQHTAGVLAERERLAREIHDTLAQGLSSIQLLLRAAQRSLGGEEGAGRYVEQARQAAADNLAEARRFVAALAPQDLEGTTLAGALERLCATTSATAPLTVRFHLAHDPGPLPAAYEVALLRIAQAALGNTVRHAGARTAEVTLSGLGDAVALDVVDDGRGFDPAALPAPDPDRGGFGIPAMRARTRALGGTLTIESRPGGGTAVAAQLPLPAEGTRPHPGPEPDPEPVPEAPR
>NC_020990.1|WP_015507393.1|2861934_2862843_-|zinc-binding-dehydrogenase
MRALVVEHGSSGPVRFAEVDEPVPSRDQALVAIRHIGLNFGELNYVDQWPAGAVHGHDASGVVVRAAADGSGPPEGTRVALGMSAHAWAERVAVDPASLAAVPEGVELADGAAPGIAGVTALRVLRTRSLLARDVLITGAGGGVGRFAVQLAALAGARVTALVGSPDRAAGLRALGADEVLTSLAGTESRFDLVLDTVGGPLLAQAWDRLAEGGTLHAVGYSSGQDTTFPSGTLFGFGAPRTLATFGDMTPTSADLTELLDLMAAGKLSAPVGRRGVWQDVDDAVQALFARKVHGKIVLDVV
>NC_020990.1|WP_003949870.1|2860957_2861905_-|AraC-family-transcriptional-regulator
MDVLAEALRVSGARGALGVVLKAGGSWGLWLDPSPAAALHVVARGTMWLHVPGGEPLEVRAGDAVLLAPGTAHGIAGGTRTTLGPCDREATVRALTDGTALHLGSAPAQTEVLVLRYERDPEVSTPVLSSLGRPMHVTSRENTQLRMTVELLTAELAHPQTGTTAAVNSIVDLLLIQFVRVWLARHPEGNSGSWLGALRDPVVRDALERVHARPEHPWTTASLAAATTVSRTTLSRRFRSALGQTPGAYLTQWRMDLAAVRLRDTDEPVESLSGAVGYASPHAFSRAFRRARGLPPGEYRVRVRAEADAWPRPLP
>NC_020990.1|WP_003949859.1|2871797_2872583_-|SGNH/GDSL-hydrolase-family-protein
MSVVRYVALGDSQTEGLGDGDEASGLRGWADRLAELLDAAEPGLRYANLAVRGQLAGQVRATQLDAALALRPDLATVVAGMNDLLRPRFDADAVGAELEAMFAALTGAGARVATLTFPAMERLVPLARPLAPRVPALNARIREAAARHGVLVVETYGEEVVVDPRLWSPDRLHAAPLGHARIAAAFADALALPGSDRGWAVPLPAVTPVRGVRALAAEARWVSGFLGPWLGRRVRGRSSADGRVAKRPGLAPLGTAGRAGD
>NC_020990.1|WP_003949858.1|2873973_2874936_+|NAD(P)/FAD-dependent-oxidoreductase
MPTPHTYDVVVIGGGAAGLAGAVTLGRARRTVLVVDAGTPRNAPAAGVHTFLSREGVSPAELLRTGRAEVTSYGGEIREGTVTDARREGDGFVVTLADGSEVSARRLLVTTGITDELPPVPGLAALWGKDVLHCPYCHGWEAQDLPTGVLATGPLSVHQALLWRQWTDDLTLFTHTTAGPTPEEREQLEARGTRIVDGEVTGVETDGEGRLAGVRLADGSTVPVRALATGGTLTARAGFLAGLGLETVPVEVGGTVIGSRLDTDATGLTSLPGVWAAGNVASPTDQVVISAGAAVRAAAVLNMDLVTEETRRAVEARRAG
>NC_020990.1|WP_003949857.1|2875030_2875342_-|hypothetical-protein
MRCVIARFPFDLVKSEVVAKMKGVKPEPVTGEYVIIGRHHYPVKQVGEVITRQDRRDFSAGEVTRALTRLGFTCRPAPGTEPAVERTAVETAAAQLGGAPEQG
>NC_020990.1|WP_003949856.1|2875520_2877032_-|DEAD/DEAH-box-helicase
MNQNRASRDDNRTGRRSGGGHRGAGAPRSAGPDRFRSPGRGGPQGARRSGGERTRAGARGEFAPPVTGTPALPPVDAFDQLGLPAPLLACLTAQGVTEPFPIQAATLPNSLAGRDILGRGRTGSGKTLAFGLALLARLEGRRAEPRSPLGLVLVPTRELAQQVTEALTPYARALRLRMTTVVGGLSLGRQASALRGGAEVVVATPGRLKDLIDRGDCRLDQVGATVLDEADQMADMGFMPQVTELLDQVRPGGQRLLFSATLDRNVDLLVRRYLDDPTVHSVDPSAGAVTTMEHHLFQVHGPDKHALATEIAARDGRVILFLDTKHAVDRLAEHLLRNGVRAAALHGGRSQAQRTRTLTQFRDGHVTALVATNVAARGIHVDDLDLVVNVDPPADHKDYLHRGGRTARAGASGSVVTLVLPEQRRSMSRLMADAGITPQTTRVRSGEAELSRITGARTPSGVPVVVRAPAPASPRRGASSSRGRRSPAAQARRAAAVRARPAA
>NC_020990.1|WP_003949855.1|2877480_2877684_-|cold-shock-protein
MATGTVKWFNAEKGFGFIEQDGGGADVFAHYSNISAQGFRELIEGQKVSFDVTQGQKGPQAENIVVA
>NC_020990.1|WP_030307725.1|2878269_2878614_+|MerR-family-transcriptional-regulator
MQVTRKTPPDPADKFDDEDYPAYTMGRAAEMIGATPAFLRAVGEARLITPLRSAGGHRRYSRYQLRVAARARELVDQGTPVEAACRIVILEDQLEEALRVNERLRDAASAAPRD
>NC_020990.1|WP_008409854.1|2878641_2879181_-|ATP-binding-protein
MTVDEGDGDLIQYRQGAARAGNGRRPAQAPRIVEAPQHRQTRRTPQVPGTAGEARALVQQALRDSFGPDATGDSDDGLGDTVVVADALLVTSELVTNAIRHGGGLTGFDVQLEESHLTLHVSDASPELPAATRPDGPFDPDRPLVGGYGWPLVRRLCREVSVRPLPGGGKCVTVTLSLV
>NC_020990.1|WP_003949852.1|2879308_2879659_-|STAS-domain-containing-protein
MLERSRMDITTSAELSAFVIGVHGDVDLHTAPALDAALAQALRAETPRTVVDLSGTGFADSSILGSLLRALRDHREKGRRLILAGPMSDLVTRLFEVTGTLAAFETAPDVRAAREQ
>NC_020990.1|WP_003949851.1|2880182_2880566_-|STAS-domain-containing-protein
MTPLNDPDDPDDLGGTGLTLTAEPAAPGTLALRLAGALDHESADALVREVARRLAERPAPRLLRLDCAGLTACDSLGLSALLMIGRRTGAAACALRLDRRPPHLDRLLEITGTHGYLVGPGEEPGPA
>NC_020990.1|WP_003949850.1|2880612_2881674_-|cobalamin-binding-protein
MTTRTPEETVTAAEPLRALLWDALLAGDEYAAADVLFAALDDGLSAEEALLDVIGPVQAEVGLGWAANRLSVVQEHAATAMNDRIIAALAHRSPPPGEGRGRIAVACVEGEWHALPARLLAETLRLRGWRVDFLGAQAPTPHLIAHLHQTGPDLVALSSSIPTRLPTAHAAITACQAAGVPVLAGGAAFGADGRYARLLGADGWAPDARSAADVAAGGLGVPSGAVLHEPVDDLPHLADQEYTLVSRGRTRLVRETVDGLDDRFPAMRGYTERQRERTAEDIAHIVDFLATALYVDDDALFTSFLVWTAGILEARGVPARSLTPALELLGEPLRDFPRATRLLHRGGAALTGG

Crispr_ID: NC_020990_16

• CRISPR_ID: NC_020990_16
• CRISPR_location: 3158452-3158709
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NC_020990_16

Consensus_repeat	Method
GTGGTCCCCGCGAGGGCGGGGGTG	CRISPRCasFinder

spacers of NC_020990_16

>16.1|3158476|37|NC_020990|CRISPRCasFinder
TTCCGGCTCGGCGGCGGGGGTTGAAGACGGTGAAGTC
>16.2|3158537|37|NC_020990|CRISPRCasFinder
TTCCGCGTATACGCAAAAGGTTGTATCGGCGAGCATT
>16.3|3158598|28|NC_020990|CRISPRCasFinder
ATCCGCCCACGGACTGGGCGACCGCCAG
>16.4|3158650|36|NC_020990|CRISPRCasFinder
GTCCGGTACGCGACTGGTGTGCGACCAGTACGTCAG

CRISPR arrays and Neighbor proteins around NC_020990_16

CRISPR arrays

The CRISPR arrays of NC_020990_16

>merge|NC_020990|16|3158452-3158709|CRISPRCasFinder
GTGGTCCCCGCGAGGGCGGGGGTGTTCCGGCTCGGCGGCGGGGGTTGAAGACGGTGAAGTCGTGGTCCCCGCGAGGGCGGGGGTGTTCCGCGTATACGCAAAAGGTTGTATCGGCGAGCATTGTGGTCCCCGCGAAGGCGGGGGTGATCCGCCCACGGACTGGGCGACCGCCAGGCCGTCCTCGCAAGGGTCGAGGTGGTCCGGTACGCGACTGGTGTGCGACCAGTACGTCAGGCGGCTCCCGCGTGCGCGGCGGTG

>NC_020990|16|13|3158452-3158709|CRISPRCasFinder
GTGGTCCCCGCGAGGGCGGGGGTG	TTCCGGCTCGGCGGCGGGGGTTGAAGACGGTGAAGTC
GTGGTCCCCGCGAGGGCGGGGGTG	TTCCGCGTATACGCAAAAGGTTGTATCGGCGAGCATT
GTGGTCCCCGCGAAGGCGGGGGTG	ATCCGCCCACGGACTGGGCGACCGCCAG
GCCGTCCTCGCAAGGGTCGAGGTG	GTCCGGTACGCGACTGGTGTGCGACCAGTACGTCAG
GCGGCTCCCGCGTGCGCGGCGGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_015507480.1|3154728_3155349_-|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|223738
NC_020990.1|WP_003949593.1|3155398_3155974_-|heme-binding-protein	unknown	unknown	gnl|CDD|377163
NC_020990.1|WP_003949596.1|3153736_3154117_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NC_020990.1|WP_003949600.1|3150527_3151478_-|alpha-L-glutamate-ligase	unknown	unknown	gnl|CDD|275040
NC_020990.1|WP_003949586.1|3162467_3162665_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949581.1|3165442_3165997_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_037630541.1|3159766_3160309_-|flavoprotein	unknown	unknown	gnl|CDD|235513
NC_020990.1|WP_003949595.1|3154279_3154687_+|RidA-family-protein	unknown	unknown	gnl|CDD|223329
NC_020990.1|WP_003949592.1|3156366_3157641_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NC_020990.1|WP_003949590.1|3159064_3159643_+|DUF4352-domain-containing-protein	unknown	unknown	gnl|CDD|378684
NC_020990.1|WP_003949591.1|3157649_3158309_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_020990.1|WP_015507478.1|3151862_3152804_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NC_020990.1|WP_015507479.1|3153040_3153733_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_026235287.1|3151481_3151670_-|hypothetical-protein	unknown	unknown	gnl|CDD|373048
NC_020990.1|WP_015507482.1|3160389_3161742_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949585.1|3162661_3162880_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949584.1|3163009_3163267_+|putative-ATP-grasp-modified-RiPP	unknown	unknown	gnl|CDD|275039
NC_020990.1|WP_015507484.1|3164158_3165430_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|275041
NC_020990.1|WP_008413778.1|3167824_3168379_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949587.1|3162030_3162471_+|ATP-binding-protein	unknown	unknown	gnl|CDD|340413

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_015507480.1|3154728_3155349_-|ankyrin-repeat-domain-containing-protein	gnl|CDD|223738	COG0666, Arp, FOG: Ankyrin repeat [General function prediction only].	6.61373e-14
NC_020990.1|WP_003949593.1|3155398_3155974_-|heme-binding-protein	gnl|CDD|377163	pfam03928, Haem_degrading, Haem-degrading. Haem_bdg is a bacterial protein that is up-regulated in response to haemin- and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein.	1.02195e-22
NC_020990.1|WP_003949596.1|3153736_3154117_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	6.12361e-31
NC_020990.1|WP_003949600.1|3150527_3151478_-|alpha-L-glutamate-ligase	gnl|CDD|275040	TIGR04187, conserved_hypothetical_protein, ATP-grasp ribosomal peptide maturase, SAV_5884 family. Members of this protein family are ATP-grasp ligase family enzymes that regularly occur in a contexts with a methyltransferase and a putative ribosomally translated post-translationally modified peptide precursor. Because of this conserved gene neighborhood and close sequence similarity to ATP-grasp enzymes from microviridin/marinostatin biosynthesis cassettes, this enzyme is suggested also to serve as a peptide maturase.	6.27073e-99
NC_020990.1|WP_037630541.1|3159766_3160309_-|flavoprotein	gnl|CDD|235513	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated.	1.40957e-06
NC_020990.1|WP_003949595.1|3154279_3154687_+|RidA-family-protein	gnl|CDD|223329	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis].	3.61696e-22
NC_020990.1|WP_003949592.1|3156366_3157641_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.39617e-49
NC_020990.1|WP_003949590.1|3159064_3159643_+|DUF4352-domain-containing-protein	gnl|CDD|378684	pfam11611, DUF4352, Domain of unknown function (DUF4352). Members of these family are putative lipoproteins that fall into the Antigen MPT63/MPB63 (immunoprotective extracellular protein) superfamily.	3.10579e-10
NC_020990.1|WP_003949591.1|3157649_3158309_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	8.12837e-69
NC_020990.1|WP_015507478.1|3151862_3152804_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.85398e-08
NC_020990.1|WP_026235287.1|3151481_3151670_-|hypothetical-protein	gnl|CDD|373048	pfam14404, Strep_pep, Ribosomally synthesized peptide in Streptomyces species. A ribosomally synthesized peptide related to microviridin and marinostatin, usually in the gene neighborhood of one or more RimK-like ATP-grasp. The gene-context suggests that it is further modified by the ATP-grasp. The peptide is predicted to function in a defensive or developmental role, or as an antibiotic.	1.21507e-25
NC_020990.1|WP_003949584.1|3163009_3163267_+|putative-ATP-grasp-modified-RiPP	gnl|CDD|275039	TIGR04186, conserved_hypothetical_protein, putative ATP-grasp target RiPP. A RiPP is a ribosomally produced, post-translationally modified peptide. This family regularly occurs next to ATP-grasp enzymes related to those of microviridin maturation and next to a methyltransferase.	3.22414e-20
NC_020990.1|WP_015507484.1|3164158_3165430_+|methyltransferase-domain-containing-protein	gnl|CDD|275041	TIGR04188, conserved_hypothetical_protein, methyltransferase, ATP-grasp peptide maturase system. Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).	2.59846e-170
NC_020990.1|WP_003949587.1|3162030_3162471_+|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	2.37273e-16

Protein sequences

>NC_020990.1|WP_003949591.1|3157649_3158309_+|response-regulator-transcription-factor
MPAPTDEPPTPAPVRLLLCDDHAVVRAGLRALLSSAPGIEVVAEAGSGEEALALTALHHPDLVLMDLQLGEGIGGVETTRRLTTLPDHPPYVLVLTTYDTDADITRAVEAGATGYLLKAERPEELFTAIRAAASGRTALSPPVAQRVMTHLRNPQPELTPRERDILRHLTQGLGNREIARALFISEATVKTHLGRIYQKLGVETRAGAVAVGKERRLLG
>NC_020990.1|WP_003949592.1|3156366_3157641_+|sensor-histidine-kinase
MRHPDDHPQPPSASPASPASGAFAPGAQTRDDRLLSALLTTAFVVLLAGALLRYVLKHGDSDRLPWIVGLSVVLAVVQVAGQARPGSRRAGRVRLAVVVACWVVVVLLAPSFAWCAVPLIHTALRLLPTRSAVALVTALATLVVLAELRLADGFDPNHLLLPPVVAALATGVFVYLTRETTRRQHLIDDLVRTRRELAATERREGTLAERQRLSREIHDSLAQGLSSQNMLLQAADRQWDTDPQAARTHLRTAASIAAHGLTEARRLVHDLAPADLAEGAGLAQALATLAARESRDGLTVRFHAEGPDTHLPDQAASALLRTAQGALANIREHSGARTAALTLTCLDDTVALDVADDGRGFPAPGPGGTRDPLGDPDPLRGHGLPAIRARLRQLGGTLAIESTPGEGAVLTATIPLTPATPPAP
>NC_020990.1|WP_003949593.1|3155398_3155974_-|heme-binding-protein
MSFSNAFRSTRTRVLTGSAVVVALGAGVFGTVSASADTAPAAKPAAAQAAADASGRNVTQTSHLTIAAATKAAQAALDAAGKEKQKVSVAVVDRDGRALVTLRGDGAGPQSYEAAQEKAFTAVSWNAPTSELVKRLDSAPTLKDIPGTLFLAGGAPVTVKGAPVAGIGVAGAPSGDLDEKFAKAGVTALFR
>NC_020990.1|WP_015507480.1|3154728_3155349_-|ankyrin-repeat-domain-containing-protein
MSRQEQRKAEARLIEAAGAGDAEGVKAALAAGARTEVSDASGRTPLLLASLGDHVAAARALVEAGADPDAQDDRDDSAWLVTGVTGSVEMMRTLLPAEPDQTLRNRFGGTALIPAAERGHVPYIRAALREASMEVDHVNGLGWTALLEAVILGDGGADHQETVRLLLAAGATPDLADRDGVTPREHAERRGFDRMAELLRKAEAAG
>NC_020990.1|WP_003949595.1|3154279_3154687_+|RidA-family-protein
MAITLVDPEGLPKVGAYRQVAVATGSRLVFVAGQVAWDADGATVGAGDLAAQVERCYLNVHTALTAAGGTFADVAKLTVYVVDWTPDKMPHFLDGVARATARLGETPAAPGTLVGVAALDVPEHLVEVEATAVLD
>NC_020990.1|WP_003949596.1|3153736_3154117_-|helix-turn-helix-transcriptional-regulator
MVTKQLSGTPEDADLSRADSLAREIFSEVANKWALLIIDALGESTVRFSEIRDRVEGISHKMLTQNLRMLERNGLVERYVHPTVPPRVDYTLTEPGLALRETTHLMCAWTQRYLGHIEGARGRFEG
>NC_020990.1|WP_015507479.1|3153040_3153733_+|hypothetical-protein
MTEQRQQDNRPPTPSRRSQRRQTVAELRSQGRAGPGLRDILPGFLGMVLVTAGPVIGLAWLYRAYGLGALLLGALLLAAATLVGVPWRRAVVRRRGGRYTPAELAVLDDHGLAVAAERILRRDGWHVLPMPDDGRPRLYARDRRDRRLDVSFRPVEGGPDAAEPPGGPATLREPGGPADDRVIRVVISMGTYSPAEIEWASRPGGDHLVDGRQLQQWASGTSLDALGLLT
>NC_020990.1|WP_015507478.1|3151862_3152804_+|helix-turn-helix-transcriptional-regulator
MPAPKSVDPTASLAALLGARIRRLRRAKGWSQTELAAKGATSQGRLAQMELGRETPSQTVCQLLDQALDADGELLALWAHIERTPYPDWSRAFMRFEQRATRMRKYMAATVPGLLQTESYVRALLAAARPSVGGALESLVRARLERRLLLTGESPPYFWAILDESVLRRPIGQPEVMREQLTYLLHMQETERVSLQVLPFSAGVHPALGGSVTVLSFDRRPDVAYLESSHSGELIDDPEAAAGYGLAFDQLHAQALSPHASAAMIRNVLEGSYGVTRVSRRRRRSVAQEQLQQHAGWGLRRGPRRPARPGSDT
>NC_020990.1|WP_026235287.1|3151481_3151670_-|hypothetical-protein
MTPFALQYARPQTGEPAAPYAFDQAEQVNVLAGGGYAAEDTALLARLGSTASTAGSKTHWDD
>NC_020990.1|WP_003949600.1|3150527_3151478_-|alpha-L-glutamate-ligase
MTVLVLTCEEDVTADAVVLQLRRRGVPVLRLDPAEFPGRVDLAVRVTPDGQVTGHLATPGGRVALEEIRSVWVRRPGTPGAHVSAEQRAWITLECERALWGALRATGARWMNDPDALERSRHKLWQLATAARAGLRVPDTLVTTDPDEAARFQKTYADAGSGLVVKSVTGRHPQNPPLTLPTAAVPPDADFTGVAACATCLQQRVPKGTDLRLTVVGDRYFPAYVTPRTPTLDWRFLPADASTWVAGEVDGALRAAVRRYLQEAQLAYAAFDFAIDEQGDPWFLEANAGGQFLFAEIETGMPMTEAIAAWLAIRRE
>NC_020990.1|WP_003949590.1|3159064_3159643_+|DUF4352-domain-containing-protein
MRRQLAIAAASFTAVLGLAACDTEVTSSPDKPAAAGDAKPGKEADKAEQAEDKETVAKVGDAITLKGFDGEKVEVTVVKVVDPAKSKDEFMAPEDGNRWLGIQFQLVNKGDKAYQDSPTNGMQVADADGQMFQTTFGEITAGPALSSDVRLAPGAKALGWVTFDVPKDVKVSQVQVALNSGMADHTGQWTLQ
>NC_020990.1|WP_037630541.1|3159766_3160309_-|flavoprotein
MTRPVLYLIATAAGPAQHVDVGIRAAQAAGWDTCLFLTPTAATWWADSMVELESLTGHPVRHRYTLPGQSGGLPKADAMLVAPLTTTSACKWAAGITDTVALGVPAEAVHLGVPVVAAPFWSTALGAQPAVGQAVETLRGQGVRVVFAEGEPHLPKRGDAAGFGWVEALAEVEQAVGGGR
>NC_020990.1|WP_015507482.1|3160389_3161742_-|hypothetical-protein
MATRKRTPNPALADLLDQARWTRTQLAQQVNRLGPQAGLHLTYDRTAVAHWIAGTPPKPEVRPLILEALSARLGRPVTHEEAGLVPASSTEGARSVDTVEELIDLGRADMDPSRRKLLATATLFSAALSVPAFQQTARAADGTASPAKAISRIGPSQVTAVRAMTERVADILDELGAGHARPMAAAFLVNTVGPWLRADATEPVRRDMLAAASDLTYLTGWMAMYEKAHGLGQTYYTKALKLADEAGDHATYCRTLRGMSLQASSLGHGRMALELADSAAEAAPSAGPRLVAFLRGQQAHAASMVGDRNQAHSRLREAESALARADNRRDAVGGYDQTAYLFHVSHVLMEEGDHAGSIKALKHSIRVQAPQERQGRVHAYATLAQRQLRHGHLDASCDSWGRFLDEYEHVASVRGDEHFATMRRDLAPHAKVRAVKELAGRAREVSAAKA
>NC_020990.1|WP_003949587.1|3162030_3162471_+|ATP-binding-protein
MAGTSNAPHPTQPHLEPAPTGHPAYTETLPCTPESAPAARRLIRQALGAWALDALADDACLVAGEMVANACRHTRSPVIRVSVTRLDGTRVEIAVTDRSHALPIRKPSRPDALDGRGLVLVDAIAARWGADPKRWGKRVWAEVRAA
>NC_020990.1|WP_003949586.1|3162467_3162665_+|hypothetical-protein
MNAYERLGTHEPLGAPGCQQCEELRDEEVQARRKFDHSRAVDCRVLLRRHPHHDSPAPPAPTAPR
>NC_020990.1|WP_003949585.1|3162661_3162880_+|hypothetical-protein
MTEPPARLPHPRRHWTPGTCWRCEAREVPVLWLGPVQTSSGTGSFTACDPCVRRLETYVRRELALRDTAPAF
>NC_020990.1|WP_003949584.1|3163009_3163267_+|putative-ATP-grasp-modified-RiPP
MPITNPRTARPWGAARLAPYPTTTHVPYCRTEIDPLTQLGVALDRHGQLVEMGKHGTSTGTETNTTTSSDGQNNDQGHDQDSDKD
>NC_020990.1|WP_015507484.1|3164158_3165430_+|methyltransferase-domain-containing-protein
MGLAGTRHRPPDGRDARRPAGRRSHPTTDPTTTERHALAARLAQSGALHTPTWRRAVESVPREAFLHPGVFLPEPRGRWRPFLADRSPEAEWTRLAYSDQSLVTQLDGSLTPDQATTPEPVPGVPTSSSTEPALVLRMLESLEVEEGQEVLEIGTGTGYSTALLCHRLGEDNVTTVDVDPGVARRADDALESIGVSTWTVTGDGLLGHPPRAPYDRVIATCAVRRVPYTWVRQTRPGGVILTTLGSWPHGGGLAKVSVGADGTAEGRIVGPVSFMQARAQAQPPVTGDLAARAAYADSEREVRVPPTVLEEWTPAFLAQLTVPDAQLVHARTAEGEQQRTYLFDPGRESFAEFVPGPRNAAGWTVRQGGPVRLWDQVEETLLAWRDAGSPGVDAVRLRVTETAHHYWLDGTSAPSLRWEHALR
>NC_020990.1|WP_003949581.1|3165442_3165997_-|hypothetical-protein
MTMTDPYTCPSCSCGQNARTVAVGPPQLEEERPETARERVNRKWNEVLQETRVAQTGISILFGFLLSVAFTSLFGELAGLDRGIYVVTVVLAALATASLIAPVSLHRFLSGLRVKDELVDAAARLMVCGMVLLALTICGTLLLILRTAVPSLLAEVLVGGVMVWFGLCWYVLPWMIRRRAGRRR
>NC_020990.1|WP_008413778.1|3167824_3168379_-|hypothetical-protein
MSNDSSAPLAENATWQALQATALGEVRRRAALVAAVVDVEPTTVDGAERLAWNDGGGQSAVWYFTADGRALLLTFDHEGSLNLYAEDDYALQVSLYRGVPEDLVALVRDRPENYESLNLTDPDSGATIHYAGGVFWFDGDSWHIADGLVAYCEQEKIELNGEAGFSYCLAPYHFGEEFPESGGK

Crispr_ID: NC_020990_17

• CRISPR_ID: NC_020990_17
• CRISPR_location: 3217982-3218437
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers

Consensus repeat of NC_020990_17

Consensus_repeat	Method
TCACGACGGTCACCACCACGGNNG	CRT

spacers of NC_020990_17

>17.1|3218006|42|NC_020990|CRT
CCGCCACGGTCACCACCGCGGTCGTCGCGACGGAAACCGCCC
>17.2|3218072|18|NC_020990|CRT
TCCCGACGGAAGCCACCC
>17.3|3218114|42|NC_020990|CRT
CCACCACGGTCACCACCGCGGTCGTCGCGACGGAAACCGCCC
>17.4|3218180|30|NC_020990|CRT
TCCCGACGGAAGCCACCCTCACGACGGTCA
>17.5|3218234|30|NC_020990|CRT
CCACCGCGGTCGTCGCGACGGAAACCGCCC
>17.6|3218288|18|NC_020990|CRT
TCCCGACGGAAGCCACCC
>17.7|3218330|42|NC_020990|CRT
CCACCACGGTCACCACCGCGGTCGTCGCGACGGAAACCGCCC
>17.8|3218396|18|NC_020990|CRT
TCCCGACGGAAACCGCCC

CRISPR arrays and Neighbor proteins around NC_020990_17

CRISPR arrays

The CRISPR arrays of NC_020990_17

>merge|NC_020990|17|3217982-3218437|CRT
TCACGACGGTCACCACCACGGAAACCGCCACGGTCACCACCGCGGTCGTCGCGACGGAAACCGCCCTCACGACGGTCACCACCACGGTCGTCCCGACGGAAGCCACCCTCACGACGGTCACCACCACGGAAGCCACCACGGTCACCACCGCGGTCGTCGCGACGGAAACCGCCCTCACGACGGTCACCACCACGGTCGTCCCGACGGAAGCCACCCTCACGACGGTCACCACCACGGAAGCCACCACGGTCACCACCGCGGTCGTCGCGACGGAAACCGCCCTCACGACGGTCACCACCACGGTCGTCCCGACGGAAGCCACCCTCACGACGGTCACCACCACGGAAGCCACCACGGTCACCACCGCGGTCGTCGCGACGGAAACCGCCCTCACGACGGTCACCACCACGGTCGTCCCGACGGAAACCGCCCTCACGACGGTCACCACCACGGTCG

>NC_020990|17|3|3217982-3218437|CRT
TCACGACGGTCACCACCACGGAAA	CCGCCACGGTCACCACCGCGGTCGTCGCGACGGAAACCGCCC
TCACGACGGTCACCACCACGGTCG	TCCCGACGGAAGCCACCC
TCACGACGGTCACCACCACGGAAG	CCACCACGGTCACCACCGCGGTCGTCGCGACGGAAACCGCCC
TCACGACGGTCACCACCACGGTCG	TCCCGACGGAAGCCACCCTCACGACGGTCA
CCACCACGGAAGCCACCACGGTCA	CCACCGCGGTCGTCGCGACGGAAACCGCCC
TCACGACGGTCACCACCACGGTCG	TCCCGACGGAAGCCACCC
TCACGACGGTCACCACCACGGAAG	CCACCACGGTCACCACCGCGGTCGTCGCGACGGAAACCGCCC
TCACGACGGTCACCACCACGGTCG	TCCCGACGGAAACCGCCC
TCACGACGGTCACCACCACGGTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003949553.1|3208506_3209082_-|TerD-family-protein	unknown	unknown	gnl|CDD|376767
NC_020990.1|WP_015507491.1|3209446_3212041_+|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl|CDD|223616
NC_020990.1|WP_003949539.1|3230707_3231790_+|amino-acid-dehydrogenase	unknown	unknown	gnl|CDD|133444
NC_020990.1|WP_010644087.1|3206312_3207503_-|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NC_020990.1|WP_015507493.1|3213270_3213855_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949542.1|3228094_3228373_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949537.1|3232963_3234034_-|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl|CDD|235439
NC_020990.1|WP_015507492.1|3212141_3212645_+|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NC_020990.1|WP_008409756.1|3232364_3232616_+|DUF3073-domain-containing-protein	unknown	unknown	gnl|CDD|378620
NC_020990.1|WP_003949550.1|3212721_3213192_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_020990.1|WP_003949546.1|3220355_3221048_-|hypothetical-protein	unknown	unknown	gnl|CDD|237864
NC_020990.1|WP_003949543.1|3223692_3227727_+|ATP-dependent-RNA-helicase-HrpA	unknown	unknown	gnl|CDD|182986
NC_020990.1|WP_015507494.1|3214263_3217320_-|FG-GAP-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|379232
NC_020990.1|WP_015507495.1|3221599_3223177_+|metallophosphoesterase	unknown	unknown	gnl|CDD|365906
NC_020990.1|WP_003949540.1|3229644_3230523_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949541.1|3228950_3229157_-|developmental-transcriptional-regulator-BldC	unknown	unknown	gnl|CDD|133390
NC_020990.1|WP_003949557.1|3203603_3204548_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381307
NC_020990.1|WP_003949545.1|3221145_3221496_+|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240572
NC_020990.1|WP_003949556.1|3204825_3205893_-|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NC_020990.1|WP_003949554.1|3207908_3208184_-|membrane-protein	unknown	unknown	gnl|CDD|182475

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003949553.1|3208506_3209082_-|TerD-family-protein	gnl|CDD|376767	pfam02342, TerD, TerD domain. The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.	1.33766e-125
NC_020990.1|WP_015507491.1|3209446_3212041_+|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl|CDD|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NC_020990.1|WP_003949539.1|3230707_3231790_+|amino-acid-dehydrogenase	gnl|CDD|133444	cd01075, NAD_bind_Leu_Phe_Val_DH, NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase. Amino acid dehydrogenase (DH) is a widely distributed family of enzymes that catalyzes the oxidative deamination of an amino acid to its keto acid and ammonia with concomitant reduction of NADP+. For example, leucine DH catalyzes the reversible oxidative deamination of L-leucine and several other straight or branched chain amino acids to the corresponding 2-oxoacid derivative. Amino acid DH -like NAD(P)-binding domains are members of the Rossmann fold superfamily and include glutamate, leucine, and phenylalanine DHs, methylene tetrahydrofolate DH, methylene-tetrahydromethanopterin DH, methylene-tetrahydropholate DH/cyclohydrolase, Shikimate DH-like proteins, malate oxidoreductases, and glutamyl tRNA reductase. Amino acid DHs catalyze the deamination of amino acids to keto acids with NAD(P)+ as a cofactor. The NAD(P)-binding Rossmann fold superfamily includes a wide variety of protein families including NAD(P)- binding domains of alcohol DHs, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate DH, lactate/malate DHs, formate/glycerate DHs, siroheme synthases, 6-phosphogluconate DH, amino acid DHs, repressor rex, NAD-binding potassium channel domain, CoA-binding, and ornithine cyclodeaminase-like domains. These domains have an alpha-beta-alpha configuration. NAD binding involves numerous hydrogen and van der Waals contacts.	1.6935e-86
NC_020990.1|WP_010644087.1|3206312_3207503_-|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	1.22929e-40
NC_020990.1|WP_003949537.1|3232963_3234034_-|phosphoribosylformylglycinamidine-cyclo-ligase	gnl|CDD|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NC_020990.1|WP_015507492.1|3212141_3212645_+|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.58162e-09
NC_020990.1|WP_008409756.1|3232364_3232616_+|DUF3073-domain-containing-protein	gnl|CDD|378620	pfam11273, DUF3073, Protein of unknown function (DUF3073). This family of proteins with unknown function appears to be restricted to Actinobacteria.	3.59284e-21
NC_020990.1|WP_003949550.1|3212721_3213192_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	8.49855e-09
NC_020990.1|WP_003949546.1|3220355_3221048_-|hypothetical-protein	gnl|CDD|237864	PRK14950, PRK14950, DNA polymerase III subunits gamma and tau; Provisional.	2.08832e-07
NC_020990.1|WP_003949543.1|3223692_3227727_+|ATP-dependent-RNA-helicase-HrpA	gnl|CDD|182986	PRK11131, PRK11131, ATP-dependent RNA helicase HrpA; Provisional.	0
NC_020990.1|WP_015507494.1|3214263_3217320_-|FG-GAP-repeat-domain-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	1.89053e-07
NC_020990.1|WP_015507495.1|3221599_3223177_+|metallophosphoesterase	gnl|CDD|365906	pfam00149, Metallophos, Calcineurin-like phosphoesterase. This family includes a diverse range of phosphoesterases, including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD or yeast MRE11. The most conserved regions in this superfamily centre around the metal chelating residues.	6.81917e-15
NC_020990.1|WP_003949541.1|3228950_3229157_-|developmental-transcriptional-regulator-BldC	gnl|CDD|133390	cd04762, HTH_MerR-trunc, Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins. Proteins in this family mostly have a truncated helix-turn-helix (HTH) MerR-like domain. They lack a portion of the C-terminal region, called Wing 2 and the long dimerization helix that is typically present in MerR-like proteins. These truncated domains are found in response regulator receiver (REC) domain proteins (i.e., CheY), cytosine-C5 specific DNA methylases, IS607 transposase-like proteins, and RacA, a bacterial protein that anchors chromosomes to cell poles.	3.77068e-14
NC_020990.1|WP_003949557.1|3203603_3204548_-|aldo/keto-reductase	gnl|CDD|381307	cd19081, AKR_AKR9C1, AKR9C family of aldo-keto reductase (AKR). Haloferax volcanii aldo-keto reductase is a founding member of aldo-keto reductase family 9 member C1 (AKR9C1).	9.85853e-162
NC_020990.1|WP_003949545.1|3221145_3221496_+|metallopeptidase-family-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	4.35845e-49
NC_020990.1|WP_003949556.1|3204825_3205893_-|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	2.19509e-35
NC_020990.1|WP_003949554.1|3207908_3208184_-|membrane-protein	gnl|CDD|182475	PRK10457, PRK10457, hypothetical protein; Provisional.	9.62673e-06

Protein sequences

>NC_020990.1|WP_015507494.1|3214263_3217320_-|FG-GAP-repeat-domain-containing-protein
MAQHARLRPTVAAVCALAVSAGLVSAVALPGTAAAAPAAAPAGAVIDAPSRFQPRVDEVFVAGEQGFLHREEGRAVEYTEYATGTTRKAENATWWNGTLGAWWSPAARTLELRPLEGEAPSVTIVLPKNQTWQRGHNASTVLTTSRETGGRTVMHLLRGAADGTVTDQEIPLGEGESFVNVLAQTHEAAVIGVRGADAAKRAFLLDYATGTTTPLFAGLASTPSRVTLTDRYVAGWDPSSPQVLTLDRRNLDAPVVRTVVPGPVKTTTRHQMALEIAGDQLLVVHQEAQPDHHIGQPLSAVRIGGGDPVTVLPHAQARLTPAPDGSVLVAGGASASDWAVHRIGAGADGRPTAAPVHALPPVAGTVRGLALAGGRLLTVGTDPVQGQPSLRSYELTTSGAPRVVSGPDTVTRSLGDYKACPDGGPSCASLTALGNGWAAHPSGNGVSVPLEQNASRVIGPMSWERPEILAATGRHVLVKERGSAKYAVGDLEKFYDSNVIHTFTATAAALWGNKVWKPATAAGTVAAYDVKTKKTAAAVDTGSGCKPTTLQAVGRWIYWACGGTKAGVFDQSLGKSVSVPAGGEPRLGDGFLVRATGEDLMVTDFSRGAGTKPATTLLASGVEPGHGIGWAVDPFGGNVAHVDADQRVHITEVPVPRSPVASIESRVEQNFVRAGGKEPWTGHWQLSRPADAWKVTFTDVTRKTVATVSGTARTAASISATWDGLATGGGKPQNGAHTWTVSVKAAGESSYVPVKTGTVQVSGGTAAYRDEQADGRGNVLTVNKNGTLTSHDFPATGVHDKWSRAGWHIKYTYVPFGDLTGDGCNDLLVRNTVGNLYRYDGVCGHPPAKTSTRTSLGGGWEAYNVLTSPGDLTGDGLPDLLARKSSTGDIWVFPGTKAGKLGAGKKIRTGWTYTHVVGAGDLNGDGHGDVLARAKDGTLYRYDGAGDGTLKSRVTVFTKWGSTYTHVLGVGDMTGDGKNDLLVVDNKGVVYRNTGNGKGSFSSRTKITTGWLTYKGIF
>NC_020990.1|WP_015507493.1|3213270_3213855_-|hypothetical-protein
MNHAQMVALGRMLRVLGESGDELRGDTPEEALHEIRADLKRALDLLEESTGPAPTTRCSQHPYGPVDKAAPDGCLLCETRRRSNHRSAYRDRWGGAPADEAGDRPLPVPSRYGIAADTPEPMVRWRPEAWSGQAWQLCGTPRRDQREAELFLAACRRKADRAAAYRLVRESTSFEVVRMWGEPIVVRPETGGGL
>NC_020990.1|WP_003949550.1|3212721_3213192_-|GNAT-family-N-acetyltransferase
MIVRPALSSDVPGLLSLAAEVEHWFGPMVDEPGFHRALDRHVREERALVAVADGGGLAGGLLFGSAPPVHHVHWIVVSERARGSGVGRALMAEAVQRYVRGPGTLEVVTFGADHPGAVTSGARAFYSSLGFSPAEQAPAGPEGGSRQVYRKVLAAG
>NC_020990.1|WP_015507492.1|3212141_3212645_+|nuclear-transport-factor-2-family-protein
MTGDKLNGMTENTTDHTTDHTTGTTFRPAGPPLPTWPAAPAPDTPSAVVTALWARMQARDWSGVAALLAPDAVVDWPVSAERLPDRDAYVAVNAAYPEGWTVHEPRVIAQGSTVVSEVRVDHEEVGTHVAVSFWTVENGLITSGREYWTMPGSDPSPPWRAHHVRPL
>NC_020990.1|WP_015507491.1|3209446_3212041_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MSLSSFGSFGGPGPDPFSDLLNRFFGMTPGASPPAVQRVPIGRLLTESARDLLGRATAKAEEDGSEDLDTEHLLWACTQVEPSRSLLARAGVDPDKLASAVEQVLPGESRTPSAEPGLTPAAKRVLIAAHARSQAADVSYIGPEHILGALLDDPNSGAGRFLQAQGTDPGALSRRADATARSEGTPSTAKPDSETPTLDEYGRDLTAEAKAGKLDPVVGRADEIEQTIEILSRRSKNNPVLIGEPGVGKTAIVEGLAQRIIAGDVPRTLHDKRVIGLDLSGLVAGAQYRGQFEERLKNVIDEVKAASESTILFIDELHTVVGAGSSGEGAMDASNMLKPALARGELHVVGATTIDEYRKHIEKDAALERRFQPVLIEEPSVPETVEILEGLRDGYEAHHGVRFSDEALAAAAELSDRYLTDRFLPDKAIDLMDQAGARVRLKSLGRSGEEIEREDELAKLTREKDEAVDAEQFERAGELKERIARIESELAGIEERREGVVEVTVDDIADVLARRTGIPVAQLTASEKEKLLKLEDALHSRVVGQDEAVTAVSQAVRRSRAGMGDPNRPTGSFLFLGPTGVGKTELAKALAELLFGDENRMVRFDMSEFQEKHTVSRLVGAPPGYVGHEEAGQLTEKVRRQPYSVLLFDEIEKAHPDVFNALLQVLDDGRLTDAQGRTVDFRNTVVIMTSNIGAQLILAHQGDVSEIKDDLMEELKTRFQPEFLNRVDATIIFQGLAEEDLSQIVDLMLERSARRVHAQGMTLEVTDAAKKLLVAHGHQPEFGARPLRRTIQTELDNRLAELMLLGEAEPGDLIVADVDNDSLVCRIEQPRKSDAPDTGGDKSGSAKSGSDKPDTPEATGASPA
>NC_020990.1|WP_003949553.1|3208506_3209082_-|TerD-family-protein
MGVSLAKGGNVSLSKEAPGLTAVLVGLGWDVRTTTGTDYDLDASALLCDESGKVLSDQHFIFYNNLTSPDGSVEHTGDNLTGEGDGDDEAVKVNLAAVPPQVTRIVFPVSIHDAESRGQSFGQVRNAFIRVVNQAGGAEIARYDLTEDASTETAMVFGELYRHGAEWKFRAVGQGYASGLAGIAQDFGVNV
>NC_020990.1|WP_003949554.1|3207908_3208184_-|membrane-protein
MEISGIISAIVIGIVIGVLGRLVVPGRQRIGLLLTIAVGIVAALVGTFVAAQFGLAETKGVDWAEWGIQIVLAAIGVFALDRVAGGRGRRR
>NC_020990.1|WP_010644087.1|3206312_3207503_-|serine/threonine-protein-phosphatase
MGKRGEDAEKETGRPAARKAPAEKRGATGRGTLGTYKGDPLTGSRSRTLMRLLPVVLLVAGVVFDEAAPPRFNASPLYAAAPLIAAPFFSLLGTVLTGALALAVVVLLQWQTGTLGGVDSTTELLTILTCALLALLSNRLVSRSGEQLATARSIAEAAQRAVLPIPAERIGGFDIAARYEAAQADALIGGDLYAVQETPHGVRLLVGDVRGKGLGAVEAVAVVIGAFREAAEQESSLEKVAQRLERALAREGVRREGLDQFEGFTTALLAEIPPGQSVVRTVNRGHPEPLLLHGDGDVRVLVPTQPALPLGMGDLGVWPDRSDATPFPSGATLLLFTDGLTEARDRNGVFYDPATRLTGRRFEAPDHLLEALSREVRVHTGGGPQDDMALLALRRP
>NC_020990.1|WP_003949556.1|3204825_3205893_-|M23-family-metallopeptidase
MASNRPAPEALFVPNDEDRVTGPTAYGPAGGPWEEWNPTEESIRPVRGRHRVAKQRGGGLARSSTVLGVGVIAAVGAGGIATAKEKPPVSISLPDLSSVKASLPDADSLPGVGSLLGSDKESDTQVTASPLTGAGVTVADTEQGTTDAGEALRARIIQQAEHQQDQADQSAARAAEQAAAEQAVAEAAKVQEAAEKKLAEAERKKAEEKRKKEEAERLAKLAASFSLPTTSYTLTSTYGQAGAMWSSGYHTGLDFAAPTGTPLKAIHSGTIKEAGWAGSYGYRTILELEDGTELWYSHQSSMSVSAGQKVTTGDVIGRVGATGNVTGPHLHLEIHPGGGDGVDPLSWLRGKGLNI
>NC_020990.1|WP_003949557.1|3203603_3204548_-|aldo/keto-reductase
MTSLRPLGNSDLDVFPLALGGNVFGWTADEAQSFAVLDAYAAAGGNFIDSADTYSSWVPGNEGGESETVIGKWLASRGNRDEIVVATKVGSHPQFKGLSAPNVKAAAEESLRRLGTDRIDLYYTHFDDPSVPVEEIVTALDDLVKEGKVRAVAASNISPERLQESLDFADREGLARYVALQPHYNLVSRDTYEGPLQQVASRAGLAAVPYYALAAGFLTGKYRPGTTVDSPRAAGAGQHLATERGQKVLAALDTVAEAHGAEVASVALAWLAARPTVAAPIASARTVEQLPALLAVADLTLTDEELSLLTVASA
>NC_020990.1|WP_003949546.1|3220355_3221048_-|hypothetical-protein
MHQLSRPVRLLAVVAAVASASGCVSVGQEADDASPVSSTASPKDGKAAPDGGTEHGTGGSGFHGGHGAGREDGAERGDGDGREGRGDGRRVRGKDGRAVEPTDEPSGPTPSPRPPSAGDPGHGGPGGGTAPNPPKGPDPKPDPSTPPPQEPGPDPEPGPTTPPVEEPGEPGGGTPPQVPDDSGRGDGRPGPAGTPSMYRQAIESAPGVAREEEPGPESGGPEGPEGSGEG
>NC_020990.1|WP_003949545.1|3221145_3221496_+|metallopeptidase-family-protein
MLEMTRDAFEELVSQALDQIPPELTRVMDNVAVFVEDEPDPSDPELLGLYEGTPLTERGEWYAGVLPDRISIYMGPTLRYCDTPEKVVDEVAVTVVHEIAHHFGIDDDRLHELGWG
>NC_020990.1|WP_015507495.1|3221599_3223177_+|metallophosphoesterase
MADATEESPRRTRAHRGQPAPESLTGTAPLLTVRPEPGPLRRWAGLTAVVLLGAWLGLLAVGSVGAPVGPMDTRMTLRPSLTGGTKINVSPLGALELDSHVAPLRLDVDVDRLDPDRSAALVQNPALFSQLGDEVSADVQDGTLHLALRSVGAVVVGATALGLIVYRRPRRALAAGGLSLVLLASCGLAAYATWNPKSVLEPKFSGLLTSAPSVVGNARSIVSEFDVYQKELARLVTNMTKLYDATSTLPAYQPDPGTLRVLHVSDIHLNPAAWHIIESLVEQYEIDVIIDSGDTMDHGSAAENAFLDPVGRLEAPYVWVRGNHDSAATQRYLGKFKNVRVLDHGKAVDVGGLRIAGIGDPAYTPDRSQEAAGDPGEVAAGMKLAAELRRQAAAGTPVDIAVAHNPVAAKETDGEVPLVLAGHLHNRKTQLLPGGTRLRIEGSTGGSGLRAIEQDSPDPVMASVLYLDRDTRQLQAWDEISLGGLGLSTAEVSRHLPEENQPGAKPSPGGSESPSPGPSTPRPNQ
>NC_020990.1|WP_003949543.1|3223692_3227727_+|ATP-dependent-RNA-helicase-HrpA
MSTISDLQPLLAELSLRDAHRLGRRLEGTRRIRKPESRAAVLEEIRAEAEKGAARMAERRARVPEIRYPEQLPVSQKKELIAEAIRDHQVVVVAGETGSGKTTQIPKICLELGRGVRGMIGHTQPRRIAARTVAERIADELDTPLGEAVGWKVRFTDQVRQDATFIKLMTDGILLAEIQTDRELRAYDTIIIDEAHERSLNIDFLLGYLAQLLPRRPDLKVVITSATIETDRFARHFGPRMATVGGKAADEDAAAPVIEVSGRTYPVEVRYRPLLEEGGEDADRDQVTAICEAVDELQAEGPGDVLVFLSGEREIRDTADALAKRNLRGTEILPLYARLSHQEQHRVFQRPGPGVRSRVVLATNVAETSLTVPGIKYVIDPGTARISRYSHRTKVQRLPIEPVSQASANQRKGRCGRTSDGVCIRLYSEEDFLARPEFTDAEILRTNLASVILQMTAAGLGDIEQFPFIDPPDHRNIRDGVQLLTELGALDPAEKDPRKRLTERGRRLAQLPVDPRLARMVLEADRNGCVREVMVIAAALSIQDPRERPSEKQAQADQQHARFRDETSDFLGFLNLWRYLRAQQKERSSSGFRRMCKAEYLNYLRIREWQDIYTQLRTVAKQMGLELREEDAADEPVHISLLSGLLSHIGMKDVKESATPAASAAKQGREGARGGRNEYLGARGAKFAVFPGSALFKKPPRFLMSAELVETSRLWARVNARIEPEWVEPLAGHLVKRTYSEPHWEKDQAAVVAYEKVTLYGVPIVAHRKVNYGRIDPEISRDLFIRNALVEGDWRTHHQFFAANRKLLTEVEELEHRARRRDIMVDDETLFDFYDQRVPAEVVSGAHFDSWWKRKQKEEPELLDFERSMLLTEAAQAVTKADYPDSWRQGGLKFRVTYQFEPGADADGVTVHIPLQVLNQVTDEGFDWQIPGLREEVVTELIRSLPKPIRRHYVPAPNYAQAFLERAAPLQEPLPVTLARELQRIVGVPVTGDDFDTSRVPDHLKITFRIVDERRRTLAEDKDLEALKLKLRPKARQALSKAAAATAERSGGPSIERSGLTDWTIGALPEVFETRRAGQPVKAYPALVDEGSSVAVRLFDSPAEQRQAMRSGIRRLILLNIPVNPAKFAADRLTNQQKLNLSANPHGSVQALFEDCATAAADRLIADHGGPAWDEEAYRKLYEKVRADLVDTTLRAIQQVQQVLAAWGAVERRLKSTRSPALLANLADVRAQVSALIHPGFVTEAGLGRLGDLKRYLVAADRRLAQMPTGVQRDTTRMAKVKEMQDEYAWLLEQLPQGRPVPKEVLEIRWMIEELRVSYFAHALGTAYPVSDKRIVKAVDAAAP
>NC_020990.1|WP_003949542.1|3228094_3228373_+|hypothetical-protein
MPESATAALPPAEDPDPPRADGVAHEAAPGPLAGIQGPPAARPRHATRALLRAHLAAAVGTRHRTGRCAVCGRLRRLAEAGAAARDEGPATG
>NC_020990.1|WP_003949541.1|3228950_3229157_-|developmental-transcriptional-regulator-BldC
MTARTPDAEPLLTPAEVATMFRVDPKTVTRWAKAGKLTSIRTLGGHRRYREAEVRALLAGIPQQRSEA
>NC_020990.1|WP_003949540.1|3229644_3230523_-|hypothetical-protein
MPQVSAVRFPYASYLRVYEPLGAFPEPERGHWERYAHEAEPPAVEEELRARLTAVLATPPLPAPERESADAFVLWSGDTPLICPWTTRLRCWEALGETAELFPPTVLDAALPPAVRERAAADHARHLERHPDARAWIRQAAWSVPLSWFVLVGDEDREYDRGAEDEAPLLRYRTPMAQARRRVARGLRALRDSVAAADPSERGVRQAGGPLVTSLVDVGRWLEEFHPRALVELDYGGLVHVLPPELLDADRSAADVASGIRALGVGDDVVAGEAYARLVERWRAVRERQFAN
>NC_020990.1|WP_003949539.1|3230707_3231790_+|amino-acid-dehydrogenase
MTDVSDGVLHTLFRSEQGGHEQVVLVQDRSSGLKAVIALHSTALGPALGGTRFYPYADEAEAVADALNLARGMSYKNALAGLDHGGGKAVIIGDPERDKTEELLLAYGRAVASLGGRYVTACDVGTYVADMDVVARENRWTTGRSPENGGAGDSSVLTAFGVYQGMRASAQHQWGDPSLRGRKVGVAGIGKVGRHLVGHLLAEGAEIVITDVREEAVRLITERHPEVTAVPDTEALIRTAGLDIYAPCALGGALNDASVPVLTAQVVCGAANNQLAHPGIEKDLADRGILYAPDYVVNAGGVIQVADELHGFDFDRCKQKAAKIFDTTLEIFARAKSDGVPPAAAADRLAEQRMAEGRRA
>NC_020990.1|WP_008409756.1|3232364_3232616_+|DUF3073-domain-containing-protein
MGRGRAKAKQTKVARQLKYNSGGTDLSRLASELGASTSSQPPNGEPFEDDEDEDPYAQYADLYNDDEDEDDESGPASKQRRGA
>NC_020990.1|WP_003949537.1|3232963_3234034_-|phosphoribosylformylglycinamidine-cyclo-ligase
MSETPTGASYAAAGVDIEAGDRAVELMKDWVRKTRRPEVLGGIGGFAGLFDASALKGYERPLLASATDGVGTKVDLARQLGVYDTIGHDLVAMVMDDIVVCGAEPLFMTDYICVGKVHPERVAAIVKGIAEGCVLAGCALVGGETAEHPGLLGPDDFDVAGAGTGVVEADRLLGPDRIREGDAVIAMASSGLHSNGYSLVRHVVFDRAGWSLDREVPEFGRTLGEELLEPTKIYSLDCLMLTRTTAVHAFSHITGGGLAANLARVVPDGLHARIDRATWTPAPVFDLIGKAGQVDRLELEKTLNMGVGMMAVVPAGSVEIALTTLRDRGVDAWVAGEITRRGDEATGATLTGDYAA

Crispr_ID: NC_020990_18

• CRISPR_ID: NC_020990_18
• CRISPR_location: 3313867-3314001
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_020990_18

Consensus_repeat	Method
GGAGCGTGGTCATGTTTCACGTGAAACATCGCCC	PILER-CR

spacers of NC_020990_18

>18.1|3313901|28|NC_020990|PILER-CR
CTCGTGGTGTTTCACGTGAAACGTCCGT
>18.2|3313963|19|NC_020990|PILER-CR
GGCGTGGCTCCAGCGGTGC

CRISPR arrays and Neighbor proteins around NC_020990_18

CRISPR arrays

The CRISPR arrays of NC_020990_18

>merge|NC_020990|18|3313867-3314001|PILER-CR
GGGGCGTTGTTTCACGTGAAACAACGCCCCTCGTGGTGTTTCACGTGAAACGTCCGTCGGGGTCATGTTTCACGTGAAACATGGCGTGGCTCCAGCGGTGCGGAGCTTGTTCGTGTTTCACGTGAAACATCGCCC

>NC_020990|18|6|3313867-3314001|PILER-CR
GGGGCGTTGTTTCACGTGAAACAACGCCCCTCGT	GGTGTTTCACGTGAAACGTCCGTCGGGG
TCATGTTTCACGTGAAACATGGCGTGGCTCCAGC	GGTGCGGAGCTTGTTCGTG
TTTCACGTGAAACATCGCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_078485295.1|3307474_3307972_+|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NC_020990.1|WP_003949456.1|3322761_3324033_+|serine--tRNA-ligase	unknown	unknown	gnl|CDD|235461
NC_020990.1|WP_003949465.1|3312350_3313829_+|aminopeptidase-P-family-protein	unknown	unknown	gnl|CDD|238520
NC_020990.1|WP_015507519.1|3319762_3321007_+|deferrochelatase/peroxidase-EfeB	unknown	unknown	gnl|CDD|273606
NC_020990.1|WP_030307454.1|3302460_3303486_-|DUF1906-domain-containing-protein	unknown	unknown	gnl|CDD|378098
NC_020990.1|WP_015507515.1|3303773_3304085_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949461.1|3316466_3317120_+|SCO-family-protein	unknown	unknown	gnl|CDD|239266
NC_020990.1|WP_003949459.1|3317713_3319756_+|membrane-protein	unknown	unknown	gnl|CDD|377255
NC_020990.1|WP_015507516.1|3309501_3310203_-|bifunctional-DNA-primase/polymerase	unknown	unknown	gnl|CDD|214927
NC_020990.1|WP_003949466.1|3310823_3312230_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NC_020990.1|WP_008416682.1|3321070_3322006_+|prephenate-dehydratase	unknown	unknown	gnl|CDD|237013
NC_020990.1|WP_003949469.1|3308126_3309116_+|SEC-C-domain-containing-protein	unknown	unknown	gnl|CDD|376935
NC_020990.1|WP_015507517.1|3314689_3315460_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949460.1|3317116_3317653_+|copper-chaperone-PCu(A)C	unknown	unknown	gnl|CDD|377298
NC_020990.1|WP_003949455.1|3324059_3324884_+|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|369792
NC_020990.1|WP_030773551.1|3301732_3302290_-|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NC_020990.1|WP_003949464.1|3314015_3314465_-|ATP-binding-protein	unknown	unknown	gnl|CDD|379279
NC_020990.1|WP_003949471.1|3306187_3307045_+|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl|CDD|176524
NC_020990.1|WP_015507518.1|3315599_3316388_+|YcnI-family-protein	unknown	unknown	gnl|CDD|377951
NC_020990.1|WP_008414403.1|3304515_3305922_-|PDZ-domain-containing-protein	unknown	unknown	gnl|CDD|273938

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_078485295.1|3307474_3307972_+|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	4.83307e-16
NC_020990.1|WP_003949456.1|3322761_3324033_+|serine--tRNA-ligase	gnl|CDD|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NC_020990.1|WP_003949465.1|3312350_3313829_+|aminopeptidase-P-family-protein	gnl|CDD|238520	cd01087, Prolidase, Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.	5.87313e-106
NC_020990.1|WP_015507519.1|3319762_3321007_+|deferrochelatase/peroxidase-EfeB	gnl|CDD|273606	TIGR01412, Probable_deferrochelatase/peroxidase_EfeN, Tat-translocated enzyme. This model represents a small family of proteins with a typical Tat (twin-arginine translocation) signal sequence, suggesting that the family is exported in a folded state, perhaps with a bound redox cofactor. Members of this family show homology to Dyp, a dye-decolorizing peroxidase from Geotrichum candidum that lacks any typical heme-binding site.	4.02345e-171
NC_020990.1|WP_030307454.1|3302460_3303486_-|DUF1906-domain-containing-protein	gnl|CDD|378098	pfam08924, DUF1906, Domain of unknown function (DUF1906). This domain is found in a set of uncharacterized hypothetical bacterial proteins.	3.30631e-41
NC_020990.1|WP_003949461.1|3316466_3317120_+|SCO-family-protein	gnl|CDD|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	1.06949e-44
NC_020990.1|WP_003949459.1|3317713_3319756_+|membrane-protein	gnl|CDD|377255	pfam04234, CopC, CopC domain. CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm.	4.29515e-23
NC_020990.1|WP_015507516.1|3309501_3310203_-|bifunctional-DNA-primase/polymerase	gnl|CDD|214927	smart00943, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal. Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities.	1.30778e-15
NC_020990.1|WP_003949466.1|3310823_3312230_+|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	2.76224e-33
NC_020990.1|WP_008416682.1|3321070_3322006_+|prephenate-dehydratase	gnl|CDD|237013	PRK11898, PRK11898, prephenate dehydratase; Provisional.	8.89356e-108
NC_020990.1|WP_003949469.1|3308126_3309116_+|SEC-C-domain-containing-protein	gnl|CDD|376935	pfam02810, SEC-C, SEC-C motif. The SEC-C motif found in the C-terminus of the SecA protein, in the middle of some SWI2 ATPases and also solo in several proteins. The motif is predicted to chelate zinc with the CXC and C[HC] pairs that constitute the most conserved feature of the motif. It is predicted to be a potential nucleic acid binding domain.	8.17443e-08
NC_020990.1|WP_003949460.1|3317116_3317653_+|copper-chaperone-PCu(A)C	gnl|CDD|377298	pfam04314, PCuAC, Copper chaperone PCu(A)C. PCu(A)C is a periplasmic copper chaperone. Its role may be to capture and transfer copper to two other copper chaperones, PrrC and Cox11, which in turn deliver Cu(I) to cytochrome c oxidase.	2.7548e-33
NC_020990.1|WP_003949455.1|3324059_3324884_+|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.95879e-60
NC_020990.1|WP_030773551.1|3301732_3302290_-|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	1.92759e-60
NC_020990.1|WP_003949464.1|3314015_3314465_-|ATP-binding-protein	gnl|CDD|379279	pfam13581, HATPase_c_2, Histidine kinase-like ATPase domain.	6.07408e-24
NC_020990.1|WP_003949471.1|3306187_3307045_+|glycerophosphodiester-phosphodiesterase	gnl|CDD|176524	cd08582, GDPD_like_2, Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in a group of uncharacterized bacterial glycerophosphodiester phosphodiesterase and similar proteins. They show high sequence similarity to Escherichia coli glycerophosphodiester phosphodiesterase, which catalyzes the degradation of glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	1.83117e-78
NC_020990.1|WP_015507518.1|3315599_3316388_+|YcnI-family-protein	gnl|CDD|377951	pfam07987, DUF1775, Domain of unkown function (DUF1775). Domain found in bacteria with undetermined function. Its structure has been determined and is an immunoglobulin-like fold.	1.5346e-59
NC_020990.1|WP_008414403.1|3304515_3305922_-|PDZ-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	2.01176e-83

Protein sequences

>NC_020990.1|WP_003949465.1|3312350_3313829_+|aminopeptidase-P-family-protein
MAEELSETPKDVDEAVADAGEQPIKQRKNGLYPALSDELAENMTQGWADTELHDLQPIEQAAETASRRAALSARFPGERLVVPAGNLKTRSNDTEYAFRSSVEYAYLTGDQTEDGVLVLEPTEAGHEATIYLLPRSNRENGEFWLDGQGELWVGRRHSLTEAEQLLGLPAKDVRELAGALAEATGPVRVVRGYDAGIEAALTDKVTAERDEELKVFLSEARLVKDAFEVRELQKAVDSTVRGFEDVVRVLDKAEATSERYIEGTFFLRARVEGNDIGYGSICAAGPHATTLHWVRNNGQVRSGDLLLLDAGVETHTLYTADVTRTLPINGTYSPLQRKIYDAVYEAQEAGIAAVRPGAKYRGFHEASQRVLATRLVEWGILEGPVDRVLELGLQRRFTLHGTGHMLGMDVHDCAVARTETYVQGTLEPGMCLTVEPGLYFQADDLTVPEEYRGIGVRIEDDILVTEDGNRNLSAALPRTSDEVERWMAELKG
>NC_020990.1|WP_003949466.1|3310823_3312230_+|serine/threonine-protein-phosphatase
MTAPHFPNVAGIDSAVPAPAQTVAPSPQPPAAPAPPPSTAVQDRLAGWVSDLTTLHELTERLIATPTVDAALRELLHAGASLVGARRGLAALEPGGPGGPRAAFTGLGLGRADLGHIETVPRAASCHGRLLDEPPGGRREICHPDLATDHTADPRHREVAARLGWAASYAAALETGSEGRFGSVVWLYDEPAEPDERRRHLTGLYLRQAGEHLARLLTLDAARATLATLREELLPSRLPRVPGVRLAARHRTGPRGGGDWYDALPLPEGALGLAIGSVTGSGPSAVAAMGRLRASLRAYAVMEGEDPVAVLSDLELLLRLTEPARSATALFGYCEPAEGPGPERGRRLVLAGAGHCPPVVVSERGAEFVETSLSAPLGMLACWEAPSVELRPRPGDTVLLYSDGLLRRTGDAMDRAFARLHSAAASVPRGRREDPGAVADHILTTLLPEGLDDEESEEDVVLLAVRFD
>NC_020990.1|WP_015507516.1|3309501_3310203_-|bifunctional-DNA-primase/polymerase
MREILGRRRKLRSRRTRGSAPAACPDLTHPTDQPDLTGVAVAAVHRHWPVVPGARPDPASPTGCGCPDPECALPGDHPADPGLLAATTDERMVRWWWSERPAAPVLLATGRGASAVSLPAVAAARALAALDRAGVATGPVLATRDRWALLVAPYSLPRLGELLYAKDHVPGSLRFHGEGGYLLLPPSAKDAGRVRWERPPAETPGGPALPEIGAVLDALVDTLNETGVNATDL
>NC_020990.1|WP_003949469.1|3308126_3309116_+|SEC-C-domain-containing-protein
MAKKRPQKPGKKAQLADGEIPVVGAREPCPCGSGRRYKACHGRAASHAVTELVQRPFEGLAGEGDWVALRELVPAATVELTLKDGLPEGVPSVTLATVLPLAWPALRREDGSVLLGLQNDTPSGDLSRDLADTLLRALEAKPGTPVEARRLPAQSASPAERPRLQELLDPEAPFAPQVHSGFEFWVPEAEAGQTSPEVTASLERANEAAIPTARLTGVEWAYWCRTPEKNHLRWVMPHSEERLLDALARLHAAGTSSLGEGTRLVGSFRAHGLTVPVWDLPTSMEAEDVEKPAAEFAERLAAALAEEAPLTAEERRARGGLTNRQVTLN
>NC_020990.1|WP_078485295.1|3307474_3307972_+|ATP-binding-protein
MAVPHGPAGVGKARRRMREQLRLSGVSDSAIDDAVLILSELLSNACRHGRPLDDAPIGDGDVRAAWRVDDRGRLTVEVTDGGGPTRPVPSTPSVTAKGGRGLNIITALSEEWGTRDGACGELTVWALLSASHRREDFAERITAPPVSALAGLDFSEALGALDDLT
>NC_020990.1|WP_003949471.1|3306187_3307045_+|glycerophosphodiester-phosphodiesterase
MPTPREAIKVIAHRGASADVPEHTLAAYRKAIEDGADGLECDVRLTSDGHLVCVHDRRVNRTSNGRGAVSALELADLAGLDFGSWKDTTRVGPVGPGAGRDTAVPVPPVSERPQWDAERTSVLTLERLLELVSDAGRRVELAIETKHPTRWAGQVEERLMTLLHRFGLAAPASAAASPVRVMSFSARSLHRVRAASPHLPTVQLMQFVGVRHRDGRLPPGVGISGPSIRILRGHPSYVEQVHRAGNRVHVWTVDEPADVALCADLGVDAVITNRPRAVLEQLGRG
>NC_020990.1|WP_008414403.1|3304515_3305922_-|PDZ-domain-containing-protein
MSTENEGSGTEGAGTEGQQVPPSVPPAPSVPPAPVDPARGGPQQSAPAGDWPPPPPQGAPSPYAEPPATPAYAGGGSYATPGGGPAWGASYQQPAPAKGRRGGLVAAVLAAALIAGGVGGGIGYWAARDGDGNSGSTTVSASDTPTSVKREAGSVAGVAAKALPSVVTIDAQGGDGEGGTGTGFVYDKQGHILTNNHVVASAADGGKLSATFSNGKKYVAEVVGRAEGYDVAVLKLRNSDGPAPLPLGNSDKVAVGDSTIAIGAPFGLSNTVTTGIISAKNRPVASSDGGNSKSSYMSALQTDASINPGNSGGPLLDSGGAVIGINSAIQSAGNGMGGSGQAGSVGLGFAIPINQAKNVAEQLIKTGKPVYPVIGASVSLEDNRMGATISDEGPGGSAAVSPNGPAAKAGLKSGDVITKLDDTIIDSGPTLIGEIWTHKPGDTVKITYERGGKTETVDVTLGDRVGDD
>NC_020990.1|WP_015507515.1|3303773_3304085_-|hypothetical-protein
MASIRTARVLAAVAALPLAAALCAGVAVADNGSFANDGSNAAVATVSGSGVGDDNSGNSATTQQQAVGSGASNENNSAQVSDSAFTSIDQSDKSVWVSFSRLW
>NC_020990.1|WP_030307454.1|3302460_3303486_-|DUF1906-domain-containing-protein
MMIRRWVALAVAVASAASAGVTAAYGDSAAPPPSPEQVLGEVAPGPSEADSAPEPSLRPRPLPASEGRPAPQPGAVAAQPVPGVPEFPPSWQFPEARQELPADANVFRGKAFDTCHAPSMGVLRNWRASDYRAVGVYFGGRGRACPNQPNLTPEYLTEGDSIGWNFLPIYVGSQSPCVIASNKQNVRITGDPVERGAAEGADAVDRAAALGMERGSALYLDMEAYDHRKADCAATTLAFVRAWNRAVTDSGYVPGFYSSASSGISHLESERRAGTTDLPAAIWFARWQPQPDLWGEPVLDREAWAPDARIHQYAGNVTETHGGSTLTIDRNQVSAPVARIG
>NC_020990.1|WP_030773551.1|3301732_3302290_-|SigE-family-RNA-polymerase-sigma-factor
MTVTQVSVRTGTSTAGGASPARYPSFASYVEARQPVLLRTARSLTPNPNDAEDLLQTALAKTYVAWPRIEDHRALDGYVRRALVNTRTSQWRKRKVDEYACEELPEPEVLPGIDPAEAQSLRDAMWRAIMKLPARQRAMVVLRYYEDLSEAQTAAILGVSVGTVKSAVSRALAKLRTDPELTAAR
>NC_020990.1|WP_003949464.1|3314015_3314465_-|ATP-binding-protein
MSIMWSLHLRRDAASVPLARRLLIGSMDTAGVDPDISYDLSVALSEACANAVEHGGAGSPAPESAYRVTAYLDGERCRIEVADSGPGFPARPARSVPMTAPQDESGRGLGLIEQLSDHAHFGNKPGRAGAVVSFDKILKWRKDAPLVAV
>NC_020990.1|WP_015507517.1|3314689_3315460_+|hypothetical-protein
MAAPHAYAQAGTGLRLLRAAVFTAVCVVVSAAGHVFASCLALPGWTLAAAFLGVFLVTVALAGRERSLPGIVLTLAAGQIGLHALFGLAQQGAARAASEATLVARAGELTCGHSGAISPHQAEQILTTAGLDPHSGSMHQHTGLAGLLPSLPMLLGHLLAALVAGWLLRRGDLALFRLVRLSALGRDELRVHGAPVRALRTALRLVRALRAGLGADGSPWTRHLAPPEPPRLRTAELQHSVSRRGPPAAEVYVLAV
>NC_020990.1|WP_015507518.1|3315599_3316388_+|YcnI-family-protein
MSVDNVTAVAPAASRRPWAVRGSVLAVAAAAGVVLLAGPASAHVSVQPQGEAAQGGYATVNFKVPNERDDASTVKLEINLPADHPLTSVMPQPVPGWDVKVTKEKLDKPLESHGNKITETVSKVTWTAEKDGVAPGTFQQFPVSLGALPDDADQLVFKAIQTYDSKEVVRWIEEPKEGEEPESPAPVLALTAASGDGHGAASDDKSAKPAASHGDDAEKASSEQAAEDSSDSTARILAVVGILIGLAGVAFGVLSGRRRTTS
>NC_020990.1|WP_003949461.1|3316466_3317120_+|SCO-family-protein
MRKKTLLAAALLSASALTLTACGGSAESDKPVASVSSDVATEKAATVLDQPFKKPDLVLTDTQGKKFDLRERTAGKPTLLYFGYTNCPDVCPLTMSNIAIAKKALPKADQEKLQVVFVSTDPEHDTPEVLGSWLKGQDPDFIGLTGDFATIQGGARTIGISIDEPTKDKNGKRVSMHGKQVIAFSPKDDAGYVMYGDDATADDYQKDLPKLLTGAKP
>NC_020990.1|WP_003949460.1|3317116_3317653_+|copper-chaperone-PCu(A)C
MRRRLLGAALALVAAASLAGCSDGGAEASGAPDLSVDGAFMPQPVNADMAAGFFKVTNKGSAADQLTSVTSPSAERVTLHSTKDGTMREQDAFEVPADGTLDFSRGGNHLMFEELTGRPAVGDTVEVTLHFSESGEIEVSLPVKEATYNPAKASGPGHGTTHPAQGRTAQEHHGTVRS
>NC_020990.1|WP_003949459.1|3317713_3319756_+|membrane-protein
MAARLLPVLLAVLLAGLAVLAGAGSAGAHAALTGSDPQQDSVVEQAPKEVALTFSEQIAVDEDAIRVLDPAGNRVDTEETPRSLGSGGAQYAVKLRAGLPDGTFTVAYQVVSADSHPVAGAFTFSIGAPSETSAAVPDQASGGGAVGALYGIARYLSYAGFTLLVGGAAFVLACWPRGAGVRPMQRLVAFSWVGLTAATLAMLLLRGPYAGSGKLGDVFDLEVLGGVLETKTGAALVSRLLLLAAAALFVAVLFGAYARREDPKERRDLTFGLTIGGTVVAVGLAATWAMSEHASTGLQAGIAMPVDVLHLLAVAAWLGGLTALLVALYRGPAVERAAVRRFSRVAFGSVVVLALTGLYQSWRQVGSWSALTGTSYGQLLLVKVGLVALLVAVAGLSRRWTGRLGEASGDSGALGSEGEGASAPGPVEPATGSAPDSGDGERAEVVAATGEASERAEAEGRPAAGRGAEAEAGAPGAESAATARVPAQADPAREAQLRRQREAASAATRKKRRDGDPERSGLRRSVLLEAGIAVVVLAVTTVLTTTEPGRTEEEAAAGTSASAAQQQGPVSLSVPFDTGGKDGKGTVLLDVDPGRSGDNALHVYVQDPGEEPLDVPELKVALTLEAQELGPLTAPLERISEGHWSATGVQIPLAGSWTVAVTVRTSDIDQVTVSKNARIG
>NC_020990.1|WP_015507519.1|3319762_3321007_+|deferrochelatase/peroxidase-EfeB
MADTPLQRPVTRRRLLGTAGATGLALGVTGAAAGYTAAAPSETVTPLAEVGSRREMFHVKHQPGITTPLHARGHLIAFDLAPGAGRKEAAALLRRWSQTAARLMAGEPAPAGGHDTGIALDAGPSALTVTFGFGHSFFARTGLEKQRPAALDPLPEFSSDRLDARRSNGDLWVQIGADDALVAFHALRAVQKDAGQAARVRWQMDGFNRSPGATEKPMTTRNLMGQIDGTNNPAPSDEDFATRVRVPADGDPAWMAGGSYVVFRRIRMLLDDWEKLSVTGQEAVMGRRKADGAPLTGGTETTEPDLERVGKDGELVIPLNAHARITRPDQNGGAAMLRRPFSYHDGIDDEGVPDAGLLFLCWQADPLRGFVPVQRKLDRGDALSAFIRHEASGLYAVPGGAPKGGYVGQELLEG
>NC_020990.1|WP_008416682.1|3321070_3322006_+|prephenate-dehydratase
MSATRYAYLGPEGTFTEAALRQLPEAATRELAPMVSVPAALDAVRAGKAAAALVPIENSVEGGITTTLDELAVGQPLMIYREVLLSISFALLVRPGTQLADIKTVTAHPAAQAQVRNWLSAHLPEAQWESAASNADGARLVQEGRYDAAFAGEFAAATYGLEPLVTEIHDAENAQTRFILVGRPARPSAPTGADKTSVVVWLGPDRPGALLELLQEFAVRGVNLMLIQSRPTGAGIGNYWFAVDAEGHIADRRVAEALMGLKRLSPDVRFLGSYPRADVRPEELAPLRPGTSDEEYVSAADWLNRCQDGRF
>NC_020990.1|WP_003949456.1|3322761_3324033_+|serine--tRNA-ligase
MIDLRLLREDPDRVRASQRARGEDVALVDALLSADERRRSSGVRFDELRSEQKSLGKLIPKATGDEKTELLKKAGELSAAVKAADAEKDEADQEAKQLLLRLGNLVHPDVPVGGEEDFAVLAKHGTIRDFAAEGFEPRDHLELGEALGAIDVERAAKVSGSRFYYLTGVGALLELALVNAAIAQATAAGFTPMLTPALVRPRAMEGTGFLGQAAEDVYHLEKDDFYLVGTSEVPLAAYHMDEIIEADKLPLRYAGFSPCFRREAGTYGKDTRGIFRVHQFDKVEMFSYVEPEDAEAEHQRLLDWEIQWLQSLELPFQVIDVASADLGSSASRKFDCEAWIPTQGKYRELTSTSNCTEFQARRLSVRMREGKKVQPLATLNGTLCAVPRTIVAILENHQQADGSVRVPEVLRPYLGGRETLDPQ
>NC_020990.1|WP_003949455.1|3324059_3324884_+|Cof-type-HAD-IIB-family-hydrolase
MSPVRPAPVFPYKLVATDLDGTLLRPDDTVSERTREALAAATAAGAAHIVVTGRSVAWTRHVLDDLGYEGIAVCGQGAQVYHAGEQRLLTSLTMDRRLAVLAIEKIEAETGPLHLAAARDGLHGEVLIGPGYQVQDGPLASVPSTDRDSLWAEPISKVYLQHPTLGDDELAAAALRIAGDLVGVVMAGPGVVELLPLGLSKATGLSLAARRLGTKGAETIAFGDMPNDIPMFGWAGHGVAMANAHRELKAVADELTTSNAEDGIAVVLERLLTG

Crispr_ID: NC_020990_19

• CRISPR_ID: NC_020990_19
• CRISPR_location: 3584471-3584566
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_19

Consensus_repeat	Method
CCAGGGCGCCAACCTCTGCCTCCT	CRISPRCasFinder

spacers of NC_020990_19

>19.1|3584495|48|NC_020990|CRISPRCasFinder
CGCCCACTGCACGACCGGCACGAACGACCCGGCCCGGGTCACCAACAC

CRISPR arrays and Neighbor proteins around NC_020990_19

CRISPR arrays

The CRISPR arrays of NC_020990_19

>merge|NC_020990|19|3584471-3584566|CRISPRCasFinder
CCAGGGCGCCAACCTCTGCCTCCTCGCCCACTGCACGACCGGCACGAACGACCCGGCCCGGGTCACCAACACCCAGGGCGCCAACCTCTGCCTCCT

>NC_020990|19|14|3584471-3584566|CRISPRCasFinder
CCAGGGCGCCAACCTCTGCCTCCT	CGCCCACTGCACGACCGGCACGAACGACCCGGCCCGGGTCACCAACAC
CCAGGGCGCCAACCTCTGCCTCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003949240.1|3567746_3568991_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NC_020990.1|WP_015507584.1|3589706_3590825_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl|CDD|227119
NC_020990.1|WP_003949233.1|3573431_3573641_-|MbtH-family-protein	unknown	unknown	gnl|CDD|377081
NC_020990.1|WP_078485268.1|3595780_3602719_+|type-IV-secretion-protein-Rhs	unknown	unknown	gnl|CDD|369438
NC_020990.1|WP_015507582.1|3585379_3585733_+|PRC-barrel-domain-containing-protein	unknown	unknown	unknown
NC_020990.1|WP_015507586.1|3592013_3595649_+|LamG-protein	unknown	unknown	gnl|CDD|379155
NC_020990.1|WP_003949238.1|3569595_3569949_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|163261
NC_020990.1|WP_003949234.1|3572412_3573435_-|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|130256
NC_020990.1|WP_008408874.1|3588555_3589710_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl|CDD|182464
NC_020990.1|WP_015507583.1|3586212_3587439_-|membrane-protein	unknown	unknown	gnl|CDD|226614
NC_020990.1|WP_003949226.1|3585869_3586235_+|PH-domain-containing-protein	unknown	unknown	gnl|CDD|377953
NC_020990.1|WP_015507585.1|3590894_3591692_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224045
NC_020990.1|WP_003949235.1|3571624_3572425_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|366444
NC_020990.1|WP_015507579.1|3569005_3569467_-|DUF2269-family-protein	unknown	unknown	gnl|CDD|370783
NC_020990.1|WP_003949228.1|3584681_3585080_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507580.1|3569945_3570632_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_008408873.1|3587619_3588309_-|hypothetical-protein	unknown	unknown	gnl|CDD|274926
NC_020990.1|WP_003949241.1|3564679_3567472_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_020990.1|WP_015507581.1|3573725_3584015_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|237108
NC_020990.1|WP_003949236.1|3570804_3571503_+|sensor-domain-containing-protein	unknown	unknown	gnl|CDD|379374

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003949240.1|3567746_3568991_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	6.61582e-87
NC_020990.1|WP_015507584.1|3589706_3590825_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl|CDD|227119	COG4779, FepG, ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism].	6.97875e-77
NC_020990.1|WP_003949233.1|3573431_3573641_-|MbtH-family-protein	gnl|CDD|377081	pfam03621, MbtH, MbtH-like protein. This domain is found in the MbtH protein as well as at the N-terminus of the antibiotic synthesis protein NIKP1. MbtH and its homologs were first noted in gene clusters involved in non-ribosomal peptides and other secondary metabolites by Quadri et al. This domain is about 70 amino acids long and contains 3 fully conserved tryptophan residues. The structure of the PA2412 protein shows it adopts a beta-beta-beta-alpha-alpha topology with the short C-terminal helix forming the tip of an overall arrowhead shape. MbtH proteins have been shown to be required for the synthesis of antibiotics, siderophores and glycopeptidolipids.	5.92022e-28
NC_020990.1|WP_078485268.1|3595780_3602719_+|type-IV-secretion-protein-Rhs	gnl|CDD|369438	pfam07591, PT-HINT, Pretoxin HINT domain. A member of the HINT superfamily of proteases that is usually found N-terminal to the toxin module in polymorphic toxin systems. The domain is predicted to function in releasing the toxin domain by autoproteolysis.	1.62417e-17
NC_020990.1|WP_015507586.1|3592013_3595649_+|LamG-protein	gnl|CDD|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	6.89776e-23
NC_020990.1|WP_003949238.1|3569595_3569949_+|PadR-family-transcriptional-regulator	gnl|CDD|163261	TIGR03433, padR_acidobact, transcriptional regulator, Acidobacterial, PadR-family. Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions].	8.53379e-30
NC_020990.1|WP_003949234.1|3572412_3573435_-|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	3.77584e-114
NC_020990.1|WP_015507583.1|3586212_3587439_-|membrane-protein	gnl|CDD|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.30021e-12
NC_020990.1|WP_003949226.1|3585869_3586235_+|PH-domain-containing-protein	gnl|CDD|377953	pfam08000, bPH_1, Bacterial PH domain. This family contains many bacterial hypothetical proteins. The structures of Structure 3hsa and Structure 3dcx show similarities to the PH or pleckstrin homology domain. First evidence of PH-like domains in bacteria suggests role in cell envelope stress response.	4.12332e-63
NC_020990.1|WP_015507585.1|3590894_3591692_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	2.31883e-134
NC_020990.1|WP_003949235.1|3571624_3572425_-|ABC-transporter-permease	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	3.50315e-20
NC_020990.1|WP_015507579.1|3569005_3569467_-|DUF2269-family-protein	gnl|CDD|370783	pfam10027, DUF2269, Predicted integral membrane protein (DUF2269). Members of this family of bacterial hypothetical integral membrane proteins have no known function.	0.00130582
NC_020990.1|WP_008408874.1|3588555_3589710_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl|CDD|182464	PRK10441, PRK10441, Fe(3+)-siderophore ABC transporter permease.	2.30416e-89
NC_020990.1|WP_003949236.1|3570804_3571503_+|sensor-domain-containing-protein	gnl|CDD|379374	pfam13796, Sensor, Putative sensor. This family is often found at the N-terminus of proteins containing pfam07730 and pfam02518. The N-termini of proteins containing these two domains often function in stimulus sensing.	3.95833e-26
NC_020990.1|WP_008408873.1|3587619_3588309_-|hypothetical-protein	gnl|CDD|274926	TIGR04025, hypothetical_protein, PPOX class probable FMN-dependent enzyme, DR_2398 family. Members of the PPOX family (see pfam01243) may contain either FMN or F420 as cofactor. This subfamily consists of proteins mostly from species that lack the capability to synthesize F420, and therefore most likely all bind FMN.	5.64901e-79
NC_020990.1|WP_003949241.1|3564679_3567472_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.36596e-06
NC_020990.1|WP_015507581.1|3573725_3584015_-|non-ribosomal-peptide-synthetase	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0

Protein sequences

>NC_020990.1|WP_015507581.1|3573725_3584015_-|non-ribosomal-peptide-synthetase
MPSVPSDRPSAAFPLTAAQRGLWFAQRLDPDSPAYNVAEYVEVRGELDVRALRRAVRHVEEETEALRLTFGERDGVPWQRVRAEAGIEVPVSDVSGYADPHAEAVRRMTAELARPADLARGPLVRMALYRLAEGHHLFHQQVHHLAVDGYGAVLALARIAEVYTLLVTAPGEPVPVRPAPLGPVLADEEAYGNSEQRSRDGEFWAAYLDGAPAPAGLVPGAPGGPARRVRAVSRHLGAEEAAGLRAAAKRAGVAWPAFLMAALGVCLHRERGLGEVVLGLPVTGRRTPAARTTPAMLSQVLPMRLAVSPADRVADVARRASAEARQVLRHQRYPAQELRRERGLGVREAQAGPAVNVLAFDDTLSFGPSPATLHNLSVGPVEDLAVAAHASYGDGGLSLDLLGDADRYDEAGLARHHEAFCRMLAAFAEDPERPLGALPLVPAPEHARLVRLGTGPVAEGGPLPTLPEQFAAQAARTPWATAVVCGDERLTFAELDARVRALSVELAARGARPGERVAVGLERSADLVTALLAVLRSGAAYLPVDPSYPVDRLAYMLQDAAPVALVARPGTAVPHEGLELVDPAAVVPGGDGGVPEPPVPEPHDAAYVIYTSGSTGRPKGVVVEHRSLAQLLEHHRREAHALAAESLGRRLRVALTAAISFDASWDPVLWMLAGHELHLADDATRRDPEALAAFLAARRIDAVETTPSHLRQLLAAGLLAGDGHHPRVLALGGEPVDDALWAELRDHDELIVLNYYGPTETTVDAVTARVTGTAPAIGRPVAGARAYVLDSALYPMPLGTPGELYLSGEGVARGYAGRPGLTARRFLPDPYGPPGARMYRTGDLARWRPEGTLEFLGRTDDQVKIRGHRVETGEVEAALRALPGIADAAVAPAGPAGGERRLAAYLVPGPGGTDPAEVRDLLTAALPDHLVPALYAVLDRLPLTPNGKLDTARLPEATAPRSAGGAPRTEDEERMCAEFAACLGLDAVGRDDDFFRLGGHSLLATRLIGRVREAFGAEVAIRALFDHPTPAGLLTALDRTAPALPPLRAARPRPARVPLSPAQRRLWLLERLGGAGTAYHLPVGLRLSGPLDREALAAALGDVAERHESLRTVVAEDADGPYQRVREPAPVPLAVAPLPRTGSPAPDPEPFDLAGEPPLRARLFTDGDRDHLLVLTFHHIAADGWSMLPLLGDLGDAYAARRAGRAPGLTPLPVQYADYALWQRELLGTPDAPTGRAARQLAHWRAALDGAPAESAPPADRPRPDRPSGRGGAVPVTVPAAVHRALLERAAASGTSPFMVLHAALAALLSRLGAGDDLVVGTPVAGRPDEALAGLVGFFVNTLALRTDTSGDPDLTTLLARVREADLAALAHQELPFEQVVSAVSPPRHPARHPLFQVMLALDNTPAPRATLDGLTVRRDTATGRTGAKFDLTWDLAERHTADGAPAGIGGELEYSEDLFDQATAERYAAQFTTLLTALLDRPDTPFTDLPFLGTRDRAAALDENGPTRPPATPDWTLTDVLATRAAADPGRTAVVDATGRLTFGELQDRAERLAQRLAAAGVRPGDRVALALPRSAAALAALLGVLRAGAVHVPLDTTHPPARNTLVLRTAAPRLVLTTATTDEAVPATGHPRLVLAEDPDDWPATGPLPAPPRPEDAAYVLYTSGSTGRPKGVVVDHRALAHLYAHHREHLIGPAQAAAGGRQLRVALTAALTFDASWDPVLWMAAGHELHLVDDATRRDPEALTAYLRERAVDVVETTPSFAELLRSCGLFAPGHHRPRVLALGGEAVTEPLWEELAALPDVTAWNLYGPTEATVDALVAPVTAGTRPHLGRALPGARARVLDARLAPAAPGATGELYLTGPGLALGYERAPAATAARFLPDPYGPPGSRMYRTGDLVRRRAGRLEYLGRADGQAKVRGFRVETGEVEAALLRHPGVTLAAATVRPGPDGSGRLLAWAVPAEGHRPTGRELRAHVATRLPSYMVPAAVVPVATLPLTVHGKTDFAALPDAPGPEAPADGTAVPRSAREEILCALFAECLGQPRVTRDDDFFALGGHSLLALGLIGRVRSAFGVELSVRTLFDATTPAALAARLDAAEPARPALRRAERPARPPLSPAQRRLWFLHGLDPADASYHIPVAVRLDGRLDRAALRDALADVTARHESLRTRVQDHEGEPCQAVLDPADARPALPTTPVTEAEVETALRAAAALPFDLAADLPLRAELFALGAERHVLLVTVHHIAADGWSMGPLAEDLAGAYAARTAGRVPQWAPLPVQYTDYTLWQADLLGDPDDAESVAGRQLAYWAEQLRGAPDEVPLPADRPRPARATGRGGTVDLTLPPATTEAVTRLARATGTSPFMVLHAALAALLTRTGAGEDLTVGTPVAGRTDEALHPLVGFFVNTLPLRVSTGGDPTFRALLARVKETDLAAYAHQDLPFERLVEEVRPARSLNRHPLFQTMLTLNNTRPPRLDLPHLAATLDGVASGGAKFDLSFSLREEDGTLTGTLEYSADRFEPGTARRIAAWFAHLTAAATAAPDTPVRQLPLHGPEEEARLLALGRGEPGEPVTGTVLDRFAATVAGARHGEPAVTAPDGTLTFAELDARARHVAALTASAGVVPGDRVAVLLPRSTDSVAALLGVLTAGAVHVPLDPALPEARLAAVLADARPRLALATTATAPLLPAGQPRLLLDQAPPAAPAPTTPRPTPDDPAYLLHTSGSTGTPKGVLVGHRSLARLLDHHRRHLFAPAVRATGRARLAVALTAALTFDAAWDPLLWLLDGHHLHLVDDQVRRDPEALVDAVRTHRLDVLETTPSHTAHLLDAGLLADGAHHPAVLALGGEAVPAPLWTRLRAAPATRCLNLYGPTEATVDTLTADLADTPHPVLGTPVTGTRAHVLDAALRPTPPGVPGDLHLAGDSLALGYPGRPAETAARFVPDPYGPPGSRMYRTGDRAVRNADGSLVFAGRADGQVKIRGFRVETGEVAAVLEAHPQIAHAAVVPHEDPEAGTTLTAHLVPAPGTDPDPEEIRAHATRHLPAYMVPTGWTTLDRLPLTAHGKLDTAALPVPRALAVPTGGRVPRTPREDVLCTLFAEALGAERVTIDDDFFALGGHSLLATRLIGRIRATLGTDLSIRTLFEAPTVAALAGRLDSAADDDSLATLLPLRTTGSLPPLFCVHPAGGLAWPYAGLLPHLDPGQPLYGLQTPNLDGTAPFPESIEEMAATYAAEIRAVQPHGPYRLLGWSFGGNVVQEIAVQLQEAGEEVALLAILDAFPLAPQDDLDSAPRDAVFRALLANLGVGEEAAEGSGGVDAAAVREEFRRAGSPLGALEPATIDAMVDNFAGQARLMRRYTPRTFHGPVLFFTATEGRPADAFPHTLWDPYLTGPLHDTPVACAHAQLMSPDARATVGPVLAEALAALAGPEATPPAP
>NC_020990.1|WP_003949233.1|3573431_3573641_-|MbtH-family-protein
MTNPFDDPRTHHRVLVNDEGQHALWPSFAAVPAGWEAVFGPADQDACHAYVEEHWTDLTPRSARRTVAA
>NC_020990.1|WP_003949234.1|3572412_3573435_-|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein
MSRARPAPPGDGPALRAEGLTKRFGTKQALAGVDLDAPAGTVLGLLGPNGAGKTTTVRVLTTLLRPDTGRAWVAGHDVRTAPEAVRARLGLSGQYAAVDEKLTGRENLYLVARLYGTGRGPARRRAAELLDRFRLSEAADRPSGTYSGGMRRRLDLAGALVARPAVVVLDEPTTGLDPRGRADTWECVRELVATGTTVLLTTQYLEEADQLADSVAVIDHGRVIAQGTAAALKSRVGGERLTLTLPDPASRPGALDLLTPLTPHRPHLDPRTGVLTLPTDHGPATLEQALAALRHAGVPLGEVSLAPPTLDDVFLALTGQETSTAPAPGPVPTKEPAWQP
>NC_020990.1|WP_003949235.1|3571624_3572425_-|ABC-transporter-permease
MAAVTRLARDATLIAWRNLLNLRRTPGSVVAALIQPVMFVLLLSYVFGGSLGGDAYRTYLMGGIFAQAVTFNAAFTALGLANDLDRGIVDRFRSLPMPPMAVILGRTLSDLTMSALTVAVTSLCGLFIGWRIAGTLPEAVLAYLLILLFAFAMSWVGATIGLTARSVEVAQSAGLIWLFPVTFLSSAFVPTATLPAALQPVADWNPVSATATALRTLFANPAPPTAPLRDTWPVTHALPYALLSTLAITAVFMGVAVRRFRAMGRG
>NC_020990.1|WP_003949236.1|3570804_3571503_+|sensor-domain-containing-protein
MATADIPTANIPTACPLPHVSEQPAGAVRRGPLSAAAWREYGYVFTSFPLAIAGFVLAVTLFSLGAGLAVTVVGFPVLVALLAGARGLGAGERGRASGLLGLRTKAPVPVPEGGIKGRLADVAGWKAVLFQFVMFPWRIASFVVTLTLLLTGWVVALLPLYAWVFPTFVGWPGYQLFDWTDGAGVRHAYYLESFWQIGAASLVGIGLVLLTPVVVRALNGVDRAAVRGLLAG
>NC_020990.1|WP_015507580.1|3569945_3570632_+|hypothetical-protein
MNPDIAPSPPLDDSVEQYAAELAAALRGPAGARERLVVEVRDGLAETVAAYEAAGVPAERAVREAVAEFGSVAEVAASCQRELTVAQARHTARALALTGPFLVACWWLVRGTGDGQGGVSGFAQQVAVQLSSAAAVAVVLAALALAATGAWGRWLPVAAERLPAAVAWTGTAASVAMAVTTLTLATTAFLAEQWPLTVLAGALAAASHAVVAGSARVCRECARLSALA
>NC_020990.1|WP_003949238.1|3569595_3569949_+|PadR-family-transcriptional-regulator
MRHDAVRGHLDGLLLAVVEPGPLHGYAIITAVQERSGGALELRTGTIYPALNRLERVGLLRSDWEAVGQRKRRRYELTEAGRRQLAEERSAWRDFTRVIGAVLDPAPVPGAATGAAT
>NC_020990.1|WP_015507579.1|3569005_3569467_-|DUF2269-family-protein
MAKLFLSLHVLAAILAIGPITVAASMFPRLARTAPTPETPALLHKICRSYAYVGAAVPVLGIATGAALGVLSDAWLVVSIVLTGVAAGVLVAVILPGQSELLEPLEGDEGAVAGEEERRAVGARLAMTTGVFNLLWAAVVVLMIVRPGSTTGA
>NC_020990.1|WP_003949240.1|3567746_3568991_+|MFS-transporter
MPLALLALSVVAFGIGTTEFVSMGLLPQIADGVGVSVPQAGNLISAYALGVVVGAPLLTGLGAKIPHKKLLLLLAGLFVVGNVASALAPGFGTLFAARVLAGLPHGALFGVGAVVASRLVAPERAARAVSTMFLGLTVANIVGVPAGTALGQQFGWRSAYLAVAVIGLIALAALARLVPHQPRAEGAGIRHELKAMGNRHIAIGLATAVVGFGGCFAVYSYLVPMLTEVTGMASSSTTLVLALYGVGMTLGTLLAGPMTDRALRPTLYGGLAVMAVVLFAFYFAVQHTVTALVCVLLIGAMGSFITTPVQMLLMAKAEQAPTMAAASNHSAFNLANAGGAWLGGLVISAGWGWASPALVGASLAAVGLGLAVVGGVMDGGFGRGKRSTVVAGAAAKAGAKDEAEVQAAGVERAG
>NC_020990.1|WP_003949241.1|3564679_3567472_+|tetratricopeptide-repeat-protein
MMDEPLERPVVVDGKIASLPFHELRSWSQFEKLVCELVQTVEHLSPCHRYGVPGQAQGGIDIAGRSEDGQWHAFQVKLVAQFSPADAKKALDQFVCGTRPYSASRLVVVVSCRDIRTQVREKVRQCQAQHPDLMLELWGAELLEFHLRLHPRIVARYFGDHVARRFCDADALETFYKAGGGIEVGSPVRDADPVGLEVHEAISADDDDDPVGTVLPAYFRRPFDGMLDTAVDQVLGGSSEMRVLLGDSSTGKTRAAWEAVQRLGDEWRLWHPADQEELLASLGAVRPRTVVWLNEINRYLLCGDSRGDEHTAARLRELLRDSRRAPVLILGTAWHVHWEAMTKVSGGGRANTRALLDRRALPVPERFTDEETAALLDQTRSADPRMLKAAREAEGGHIIQFLAGGPAQWERYSNGSATAQAVLHAAMDARRLGHGVDLPRRFLQTAAASYLTVLQRDLAEPDWFPRALEYLSAPCRGVRGPLAPIPGFSVSGASTARNYRLADYVESHGRRHRGLICPTDEFWEAAAEYSANPRDKVALSSSALARERITQAETLALAAAEDGEGAALSHLASWIRENRKEEDPHTCYELAADVGDAVAQVEVAFRAEREGKLEKAEGWYRKAVDQDSRRWDAMVGLASVATQRGDSAGAAEWYDRALGAGFFGARAVEDQARWLAGRGQHELALLLTGYSFRAGNAEAFTGLAWTYMYKDTTRAIEVFEYAMAEGDVNAPKELCWVLEQEGRSDEADHFCEIAVGLGETNALRGLGMIRRSKGNHRGAAALFWRAYNNNLTYALFELAHLREEQGDLKRAERIYRRAANEGQPGAAEQLVRVLETRGRTQQAELLAGSSHECLEALALARAARGAYESAEQLLLGQVAKGHTRLLVTLARIREQRGDTAGAERMLRRALDAGVPFAARRLAELLKDGQM
>NC_020990.1|WP_003949228.1|3584681_3585080_-|hypothetical-protein
MTKHHAARILIGAGAAFGLVLGATGAANAAPSNPIKTQGGYAQWNADPSGSIPGDSIRACDNTADGWGIEAWLDINRDGTIDRIASTRGHNAPYCTSWKSGDIPEGTPVTVYAVTVNGGIVLEKGGALWSKA
>NC_020990.1|WP_015507582.1|3585379_3585733_+|PRC-barrel-domain-containing-protein
MSDGIWGYQPTAGHTAGTDLIGYKVEATDGTIGKVDKHSDEVGSAYLVVDTGVWIFGKHVMLPAGTVRTVDGAERKIHVELTKEQIKNSPEFDKDRHAGDAQYHDQLGGYYGGHRPL
>NC_020990.1|WP_003949226.1|3585869_3586235_+|PH-domain-containing-protein
MALFGNAHTVDPGSAQQEYARLLGQGEQVHAAYLLIRDTILFTDRRLILVDKQGITGKKVEYHSIPYRSITHFAVETAGTFDLDAELKIWLSGATTPVQKTFTKGVDIYEVQAILTQFVTR
>NC_020990.1|WP_015507583.1|3586212_3587439_-|membrane-protein
MSDTATREKWERVADWGRRLRRPESSARRSLLLILKSALAATVSWFVSYELMNATSPAFAPFSAVLMVQVTVYQSVVQSLRYVGAVAAGVAVQAVLGLSAGPDLVTFALVALVALVISRWRLLGAQGSQVATAAFFAFATYTGASSDTDQVKELGQIVLLVLIGSAVGVGVNVLIAPPLRYRSAEWGIRALAQEIHDLLDTMAPELGEGAPDADTTQGWRDRADRTGTLISQSREGLRTARESLRLNPHPWARRRRGTLTFEAYDRTMEALVRMISQVTAITRSLDLQHQDEKQQEEESGPDRDYAPFLRAYATFLSSVVDFTEILATLDEDHLRDQAGRLDEAADGLERCRREVVRTTEDRGLSLTDPTEPYGVLVVEATRLSEECRYTAGVLGNSADNGSSGSRTA
>NC_020990.1|WP_008408873.1|3587619_3588309_-|hypothetical-protein
MTNPAPEAPATGLHHSLARLTRVPDARGLGLTGPAVPAAPLVPEAPATSPLPAGYTELTGVEELDALLGVPHPIVIDKVHDRLDAQDLDLLSRSSFCSLSTADAEGNCDVSPRGGVPGFTHVVDPGTLALPDRPGNRRGDSFRNILTNPHVGLLYLVPGVMDVLRINGRARILTDAPFFDALVEKNQRPKLALVVEIDEIYRHCPASLRRSGIWSPDTWENAAGGTSPA
>NC_020990.1|WP_008408874.1|3588555_3589710_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MNGPADREGRPADPSGTPPSRTRSTALLDLDKRPDAEGATAIAAPPPRRSVRSRPALAAGLVLALVGLGLTLVASLAVGSGDVPFADVLGTFLDPDAENKAQLIVGEVRIPRTVAGLLSGVALGLAGTVMQGVTRNPIADPSLLGINAGASLSVVFAISVLGLGASQQYLWFGFLGALIAALVVYGVGSLGREGATPVKLALAGAATTAVLTSLTTTMLLTDRQSYDQFRFWQIGALNTRSVEVLSEAAPFIVVGGLLALTLGSQLNALALGDDLARGFGQRVGLVRGVSAVAVVLLCGASTVVAGPIGFVGLAVPHIARLVTGPDYRWVLPYSMVLAPMLLLWADIVGRVVAQPGEVQVGVVTAALGCVPFIWLVRRRKLVEL
>NC_020990.1|WP_015507584.1|3589706_3590825_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MSDRATSSFEKAAPARTDASPLHVSEAVLAEAARTVAGARRRGGRRSVLVGLVLALAAFAVFAVSLSVGDMVIPLADVLATLFGGGDAGSQFVVLELRLPRALLAVLVGAGFGMAGAVFQTVLRNPLASPDVIGISSGASAAAVTASMVFAVSGLALSASALIGALIAGTLIYLLAWRKGVVGARLVLVGLGVGFGLNSLVWYLMSRAEVTGAQNALLWLTGSLNGRSWNQVWPQLIALAVLVPLTFAAARALPALQLGDDTASGLGARAERNRLALLACGVALAGASTAAAGPVAFVAFVAAPVARMLLPGRGAVLPHAALAGALLVLLADFAAQHALPGTQLPVGVVTSVVGAPYLLWLLARANRVGRGG
>NC_020990.1|WP_015507585.1|3590894_3591692_+|ABC-transporter-ATP-binding-protein
MSAEHTLEARDVRIGYDGREIVPGLSVKIPPGRFTVIVGPNACGKSTLLRAMARLLAPTSGAVLLDGRPVQQTPTREVASVLGILPQSPVAPEGITVSDLVARGRYPHQGWFRRWTAEDDAAVGAALLSTDVLDLAERPVDELSGGQRQRVWIAMALAQRTDILLLDEPTTFLDVAHQMDVLDLLTDLKRERGVTLVAVLHELNMACRYADHLIAMKQGEVVAEGAPSDIVTEQLVSDVFGMRCSVVPDPASGTPLVVPLGRHHV
>NC_020990.1|WP_015507586.1|3592013_3595649_+|LamG-protein
MLAGALTGALVQVPYVAQAASEPEPAELSEGQEALAAAVESGERVEVLGQRSERTTVYANPDGFTFTLQESSIPVRVSKPGGGWQAPDATLVRHEDGSVGPKAAAPQILFSGGGEKEPLASIASQGKSLELSWPEALPRPVLEGASAVYPEVLPDVDLKVTATAESFQHVLVVKTPEAAASEKLKKLTFGLKTTGLDLEEGATGNLTAVDANGNTVFRSPPAQMWNSAGKTLSPASPAAKGASRATVDEKEPSDPAEAAPSGSGLEPGQGDKFTKMDVEVEETSLSIVPDAEMMREKDASVYPLFIDPPVTWGESERTLLRSDGYEDYAWGNGEDDLGKGAGKCGVWNNYYCGPGYVQRLYFEFSPAKLKGKKVLDATFRVTEPWAFQCEPRWVDLVRTKENISSSTTWASRPMGWDTMGDRHVSAGRGDLCSPGLPNAEIEFNDNPDESNENLTPTVRDFAAGKFSRLTLMIKAHDETDTAAWKRFKNDAVLEVDFVGIPDKPTGIGLVTGSGTVCSTTESNPSIVSDPTPLLSATTQTKSGGEEDAQLRIYFDIDNKKSDGSWADTSAGNGNERPSTGYVADGKRQTMSWSTLTEGTLYRYRAWTQSYYNGGKSFLSGPSNGSTSGFCYFKVDPTAPRPPNIKLNIPYKECLPNDCPARGGPGQRSAFVLQPAAGDTGVVSYQYTLSGMSTWPTAEGATALVPLVPSRPGTHTLWARAKDKVGRYGAWNAVDFVVAAGDGPVARYHFDEASGAAVDSATADGKDDATLSAGAVRTDHGRRGLVTHDAKGEPLASPAEDKGLELNGTTGHAATAGPVLETRSSYTVSAWVRVDPSATKTVSVLSQSPSSPYPFTKKYSPFVISYGGKWSIRAFSSEGTFSREAAAVEAHPKGVWTHVAAVHDATDKKLTLYVNGVRQAEVDAGTPWSAEGSLEIGRVMYADAYTDSFKGEIDEVVAWQRALTPDEVHDEARLLISGQYAGTELIADWNPARGVDGGAVNDTTSGYGKRLTLSGATVAGEEIVLDGVDDTATAPGPLVDGSGSFTVTTGVTLDAAKLLTKDIGYIGQVAGQRTADGSAWGLWFQLTEKQTVLDEKTLEEVTVPVGLWHFGRLEADGKFSSVASEEVASVDSSARLTGVHDSVDGTISLYIGYGRNGDAKVYTAKIGSGDFALGKAFAGGAWKHFLPARIAEIRLWAGAMASAEQVETAVGD
>NC_020990.1|WP_078485268.1|3595780_3602719_+|type-IV-secretion-protein-Rhs
MRFGIGTSNRGAGGRRRWGRRLIVPALALALLVPVGEAPSAVAKEQGLGQPELPKPRVSKVAEVKAPGAKKARQKVAEGKQRGEAQSRRAATEQKTSWPERGTATARLVQGAPRKLSLDGTTVTVTPRKVKRERGAAGEARVTVLDQKAARRAGVTGVLLTATAETAGSAKISVDYGDFASAIGGGWAQRLRLVELPACALTTPEKAACRKQAPLESENDPGDQSVTAQVAVSEQASGAVAQKSAGAPTVLALTAQAAGAGESPQGSGDYSATELSASSSWTAGGSSGAFTWNYDFSLPPAAAGPVPSLALSYDSGSVDGRTATTNNQGSAVGEGFSLTESYIERSYGSCDDDGHDDVFDRCWKYDNARIVLDGRSSRLIKVSDKEWRLEDDDASTVTRSTGADNGDNDGEYWTVVTGNGTKYLFGLNKLDGAADQRTNSTWTVPVFGDDSGEPGYDKGGAFADRSLTQAWRWNLDQVEDTAGNASTYWYAKESNHYKKNKAETATASYTRGGYLKEIKYGLRKDALFTDDADAKVTFSHAERCTVGDCKELTESTAKHWPDVPFDAICSDGDKECNSAGASFFSRKRLTGVETYSWDATTKKYSPVDSWTLGQDYKDAGDIGDTTDHVLVLESIKRTGKAGTDVGVNPVTFTYQLRPNRVDATDDILPLKRHRVETITSETGAITTVTLSSPECKRSEVLGAPQDTNTRSCYPQYWNINGASEASVDWFHKYRVLAVAVADPTGHNEDVEHAYDYAGAAWHHLDEPFTPKDERTWSDWRGYRDVTVYSGATQTTRSKTVSRYLQGMDGDRKKDGTKTASVEPLLDTDVDFGSVADADRYRGLLRQQVTYNGNQPISSTFNSYAHKTTATQTVPGADDHTARWVRPATTYSSTYLTASKNWRTRQTTNTHDDLGMVTTVDDYGQRGVAGDETCTRTWYARNDAVGINNLVSRSRTVAKECAVSDTALDLPGDSTRRGDVLTDTAIAYDGATTWSATAKPAKGLITWTGRAKGYTGGTPSWQTQTTTANADYDALGRATKITNADGKTTTTEYTPAAAGPLTKSIVTDPKGHKTTSFLDPRRGQPLRTYDANLKKTESTYDGLGRLTQVWLPNRSSGSQSPNQKYAYHLSNTKQSWVSSSSLKKDGESYLTSYAIYDALLRPLQTQTESARGGRLLTDTRYDTRGLAYETYADIFDTTSSPNGTYTRAEYGEAPTQTETVYDGAGRAVSNTVLIYGNKKWTVGTSYTGDSTATTAVQGGTGARVITDVRGRTTESREYAGRSPSDAQYGDGPGAGYASTKYVHTPDGKNSQITGPDDAKWSYGYDLFGRLSTSKDPDKGSVTTQYDALDRAVKTTDSRGKSVLTEYDELSRVTGTWAGSRTDATQLTAYTYDTLLKGLPVAATRYVGGKPGQAYTDTVTAYDTLSRPKTSKLDLPAGDAFVKAGVPASLTYETEYNLDGTVKTVKEPALGGLPSEVLEYGYNSVGQVTSLGGSTGYLLDTTHTPLGQPQLLTLGTANTADHKKVYLSNSWEEGTGRLVRSSVTDQTHSYMLQDLNYAYDDAGNVTSITDPTTVGGTSSAETQCFVYDGHRRLTEAWTPSSQKCGDPRSADQLSGPAPYWTSYEYNKAGQRTSETAHAPAAETTTNYCYTKNDQPHFLTGTTTKGSCATPEKTYTPDSAGNTAKRPGAAGTQDLTWSEEGRLTKLTEGSKSTDYLYDAAGELLIRATQGADRVLYAGATELHLRADGTTWAQRSYTAEDRTVAVRSNEGETNKLTYLTGDHHGTQSVAIGADATQTVNKRHLTPFGAERGKPTNGAWPDDKGFLGKTNDKTTGLTHIGARQYDPAIGQFISVDPILDLTQPQSLNGYSYASNTPVTMWDPTGLAGIGGGNPGAPGNSGSKMPYGGELGDWEDAPSSAGKPLPTFSSVHVSGKSSGIEPITNIGYGESPLPPPDVYQQWQEFLPSVVQMRNLGTYVAQLGYALNVELFFREHCSVSPSGDACQSLRDFYATGKGADRTNWGHVQGLPGVNKCDICQNIGFDLLMAGIPAGRGKGSTPQCFLAGTDVVMADGSTKDIEDIEVGDLVLSTDPETGKTGAKKVTKLSQTVGEKHLNELSIATEDGVEQLTATGEHPFWSPSEKSWIAAGDLTSGMSLLTSDGQTAIVTGNRGYTSYAVTYNFAVEDWHAYYVLAGETPVLVHNSGGFCGPGLRTASEAGISPNDAKRIQNAADKAGQPIIVVGSRANGTPNPTSDWDYILSGPSRTRHSVKNSLPRGTGDGEGSGRGRDFWQNYNPNRPDYAELDPSRPYVVFGPRSR

Crispr_ID: NC_020990_20

• CRISPR_ID: NC_020990_20
• CRISPR_location: 3794142-3794228
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NC_020990_20

Consensus_repeat	Method
AGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NC_020990_20

>20.1|3794165|41|NC_020990|CRISPRCasFinder
ATCGGTGACCGGCACGGTCGAGACGGAGCCCGGCAACCCAC

CRISPR arrays and Neighbor proteins around NC_020990_20

CRISPR arrays

The CRISPR arrays of NC_020990_20

>merge|NC_020990|20|3794142-3794228|CRISPRCasFinder
AGCCCGGCCGGCGCTTGAGGCCAATCGGTGACCGGCACGGTCGAGACGGAGCCCGGCAACCCACAGCCCGGCCGGCGCTTGAGGCCA

>NC_020990|20|15|3794142-3794228|CRISPRCasFinder
AGCCCGGCCGGCGCTTGAGGCCA	ATCGGTGACCGGCACGGTCGAGACGGAGCCCGGCAACCCAC
AGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003949017.1|3795196_3795922_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_020990.1|WP_008415428.1|3799809_3800664_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|366166
NC_020990.1|WP_003949019.1|3792769_3793555_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|367243
NC_020990.1|WP_003949014.1|3797440_3798112_-|haloacid-dehalogenase-type-II	unknown	unknown	gnl|CDD|319787
NC_020990.1|WP_003949015.1|3797063_3797423_+|glyoxalase	unknown	unknown	gnl|CDD|319922
NC_020990.1|WP_003949024.1|3788376_3788583_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NC_020990.1|WP_008415470.1|3786974_3787196_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949010.1|3801632_3802271_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl|CDD|274422
NC_020990.1|WP_003949025.1|3787540_3788380_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NC_020990.1|WP_015507636.1|3802287_3803085_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507633.1|3795918_3796947_-|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NC_020990.1|WP_003949026.1|3787192_3787372_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003949028.1|3786220_3786958_+|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NC_020990.1|WP_003949011.1|3800758_3801517_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_020990.1|WP_003949020.1|3791677_3792664_-|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|130256
NC_020990.1|WP_003949021.1|3790941_3791685_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|272861
NC_020990.1|WP_003949029.1|3785466_3786102_+|flavodoxin-family-protein	unknown	unknown	gnl|CDD|376808
NC_020990.1|WP_003949023.1|3788735_3789026_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NC_020990.1|WP_015507632.1|3794256_3794901_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NC_020990.1|WP_003949013.1|3798339_3799779_+|rifampin-monooxygenase	unknown	unknown	gnl|CDD|235870

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_020990.1|WP_015507633.1|3795918_3796947_-|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	2.8e-34	113.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003949017.1|3795196_3795922_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	5.58897e-21
NC_020990.1|WP_008415428.1|3799809_3800664_-|alpha/beta-fold-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.08253e-11
NC_020990.1|WP_003949019.1|3792769_3793555_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	2.83247e-11
NC_020990.1|WP_003949014.1|3797440_3798112_-|haloacid-dehalogenase-type-II	gnl|CDD|319787	cd02588, HAD_L2-DEX, L-2-haloacid dehalogenase. L-2-Haloacid dehalogenase catalyzes the hydrolytic dehalogenation of L-2-haloacids to produce the corresponding D-2-hydroxyacids with an inversion of the C2-configuration. 2-haloacid dehalogenases are of interest for their potential to degrade recalcitrant halogenated environmental pollutants and their use in the synthesis of industrial chemicals. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.05358e-42
NC_020990.1|WP_003949015.1|3797063_3797423_+|glyoxalase	gnl|CDD|319922	cd07261, EhpR_like, phenazine resistance protein, EhpR. Phenazine resistance protein (EhpR) in Enterobacter agglomerans confers resistance by binding D-alanyl-griseoluteic acid and acting as a chaperone involved in exporting the antibiotic rather than by altering it chemically. EhpR is evolutionarily related to glyoxalase I and type I extradiol dioxygenases.	3.42669e-32
NC_020990.1|WP_003949024.1|3788376_3788583_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.40523e-19
NC_020990.1|WP_003949010.1|3801632_3802271_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl|CDD|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	2.82757e-22
NC_020990.1|WP_003949025.1|3787540_3788380_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.23989e-06
NC_020990.1|WP_015507633.1|3795918_3796947_-|WYL-domain-containing-protein	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	6.30478e-28
NC_020990.1|WP_003949028.1|3786220_3786958_+|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	1.68216e-10
NC_020990.1|WP_003949011.1|3800758_3801517_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.9925e-18
NC_020990.1|WP_003949020.1|3791677_3792664_-|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	1.67528e-108
NC_020990.1|WP_003949021.1|3790941_3791685_-|ABC-transporter-permease	gnl|CDD|272861	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family. The seed members for this model are a paralogous family of Mycobacterium tuberculosis. Nearly all proteins scoring above the noise cutoff are from high-GC Gram-positive organisms. The members of this paralogous family of efflux proteins are all found in operons with ATP-binding chain partners. They are related to a putative daunorubicin resistance efflux protein of Streptomyces peucetius. This model represents a branch of a larger superfamily that also includes NodJ, a part of the NodIJ pair of nodulation-triggering signal efflux proteins. The members of this branch may all act in antibiotic resistance.	4.5513e-15
NC_020990.1|WP_003949029.1|3785466_3786102_+|flavodoxin-family-protein	gnl|CDD|376808	pfam02525, Flavodoxin_2, Flavodoxin-like fold. This family consists of a domain with a flavodoxin-like fold. The family includes bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC:1.6.99.2. These enzymes catalyze the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species. This enzyme uses a FAD co-factor. The equation for this reaction is:- NAD(P)H + acceptor <=> NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy. The family also includes acyl carrier protein phosphodiesterase EC:3.1.4.14. This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP. This family is related to pfam03358 and pfam00258.	1.89438e-12
NC_020990.1|WP_003949023.1|3788735_3789026_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	4.17963e-21
NC_020990.1|WP_015507632.1|3794256_3794901_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	3.44709e-25
NC_020990.1|WP_003949013.1|3798339_3799779_+|rifampin-monooxygenase	gnl|CDD|235870	PRK06834, PRK06834, hypothetical protein; Provisional.	3.18655e-162

Protein sequences

>NC_020990.1|WP_003949019.1|3792769_3793555_+|TetR/AcrR-family-transcriptional-regulator
MAPPPPERRDPADETGLPASVEAAWGLRGRPTKGPRPGIGVERIVDAAVKLAATEGLQAVSMGRVAKELGASTMSLYRYVAAKDELFILMQEAATGLPPEDAPPPSAGWRARLAWFGHAYRGVLEANLWLLHIPISSPPATPNSVAWMEAGLDALDGTGLDEATKLGVMMLISGYVRSQAGLMADLTEAMRRSGRSAEDTHRQYIHTLTRLADQRGPEAFPAVRRLLASQVLGEGDDADADFDWGLHRVLDGVQVLIEGRA
>NC_020990.1|WP_003949020.1|3791677_3792664_-|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein
MRQPPHAAVEVQGLSKSYGDHAVLRSVDLRVEQGGVLALLGPNGAGKTTTVRVLTTLTDPDAGSVRVAGYDVVTERRRAQRAISLTGQFAAVDETQTGAENLWTTARLAGLTRAAARRRAAELLERFALTDAGGRLVRTYSGGMRRRLDLAAGLVGEPRVLFLDEPTTGLDPRSRRQLWEVVRELAAAGTAVLLTTQYLEEADQLADRVAVLHGGRIAAEGTPEELKASAGQTVLEVTAADAAAFARLEARTPHPVAHRSPETLALSFPTRGDARHLRTLLDELDPGRDEITAFHVRQATLDDVFMALTGAPATETTGTTDAKEPSHV
>NC_020990.1|WP_003949021.1|3790941_3791685_-|ABC-transporter-permease
MSEALTLAGRCLRMNRRDPEALFMAILLPVALMLVFVYFFGGAIDTGSAYVTYVVPGLLVLCAGYGSAGTAMRVTEDMRTGVVDRLRSMGVTGTPMLAGHVAASVVRNILATAMVLSVALLIGFRPAADPLAWLAAAGLLLAYLIAVSWLAAGVGLLARTPEGASGFTFFLMFLPYPSSAFVPIETMPTWLHGFAEHQPVTPLIESLRALLLDEPLGSAPWTALAWCGGILLIAVAASNALFRRRTR
>NC_020990.1|WP_003949023.1|3788735_3789026_+|DUF397-domain-containing-protein
MTPNSPYWRKSSYSSNGGDCVEVHIPPALDASPDWFKSSHSSNGGQCVEVAANLVPTHDLVPVRDSKTPSGPVLTFPATAFSSFVAGVKAGEFRSA
>NC_020990.1|WP_003949024.1|3788376_3788583_+|DUF397-domain-containing-protein
MTSEPHWFKSSYSNNGGVCVEVAINLAAPHGIVPVRDSKVQSGPVLTVPATAFSSFVAGVKAGTLRSA
>NC_020990.1|WP_003949025.1|3787540_3788380_+|helix-turn-helix-domain-containing-protein
MVNRKELNPEASPHAAFGAKLRVVREAQGLTQDQLGSAMGYTCGHISSVETGRKVPTLRFSRQVDQALGTANTEDSFERQWREIRQGSLLEGAPEYMGCEARSAEIRLYEVGVVPGLLQTPEYALTLAEGAVLRGSITEEQAAERVQMIADRQEALSRRSPPMVFVVLDESCLRRPVGEPTIMNAQLEYLMEFADRPNTMVQVAPFDLGARRPFDLPIYILTMPDRQLMSYAESAQRDHLDRESTSVLPLLTAYHQLQALALSQAASVAMISQLRKGTP
>NC_020990.1|WP_003949026.1|3787192_3787372_-|hypothetical-protein
MSAVDSPHGKGDQPCTTCESWKLAEAVANGEQDYSRATDCRVLLKRHRESAECQAGGEG
>NC_020990.1|WP_008415470.1|3786974_3787196_-|hypothetical-protein
MSAGYEPPGKAYREFDPLRFPPCACEGCRRRAALESQAPPPTEPVPAPEQPRYVRCPMLGCGRLHPALPDDPG
>NC_020990.1|WP_003949028.1|3786220_3786958_+|HAD-family-phosphatase
MTSSTHPPEPTADELAGLRDLVAAAKTVIVGFDGPLCRLYDPLTARTAADSLTALLAEHGVPAGDVPGRTPLALLRSLTLGALDDDPALSTALDELLTGSEVAATLTARPAPYADNLVRTWSAVGTRLAVATGHSADAVHAYLAGRGLTACFGPHVYGRTDGLTHLGHDAPPRALAALGADPAEALVLGSTPEDLRAARDAGAPFLGYARDLPAYDRLRAAGAPLVTGTLEPVRQAVWELNLPRR
>NC_020990.1|WP_003949029.1|3785466_3786102_+|flavodoxin-family-protein
MTSFPTQAPDQDQNQDRSFLFVLGSSRPDGNTAQLARAAAEHLPAAYGRRWIDLNDLDLPDFQDGRHEGERWQPGEAEATLYEATVAATDIVIATPLYWYSFSAQTKRYLDYWSGWLTLPGSDFAARMAGRRLWGVTVMADRDEVVAGGLDTSLHHTAAYLKMGYGGILLGNGSRPGQVAVDERAQRRAKTFFAGPTPLARFPHEEAAEAA
>NC_020990.1|WP_015507632.1|3794256_3794901_-|histidine-phosphatase-family-protein
MTSTAATGMASRTLYLARHGDAPGEGGLSAQGRRRQAAFLGERLRGVPLSAIHHGPQARARETAEIVAAQRDDEEPEPRACDSAGDYVPYLPERREVASGLPEATWEWLLQLPERERLPGPELARDALRRFTGAVPGGVARHELVVTHNFVIGWLVREALDAPDWRWIGLHHANAALSIIHYAPEGPSSLIVYNDIRHLPEELRWTGFPPGLRV
>NC_020990.1|WP_003949017.1|3795196_3795922_-|class-I-SAM-dependent-methyltransferase
MTALSEPTETTETADAATRASYDTVATTYEQLLRAELDARPLERALLAAFAELVRGPESGPVADLGCGPGRITAHLADLGVNAYGIDLSPGMVAVARERHPHLRFDEGTMAALRHRDGELGGAVAWYSTVHIEPGLLPGVYAEIHRVLAPGGRLLLAYKAGERVRHLDHAYGHPLSLDVYWVPPGEVEGLLRAAGFTVEATMTRRPDAGDGPRAGDQGFVLARKPLAVAGAEAASLPKSGA
>NC_020990.1|WP_015507633.1|3795918_3796947_-|WYL-domain-containing-protein
MTPDRFFALLLALQTRRDPVTTTDLAAETGVSVRTVLRDLRWLQDAGFPVLVERGRWGGVTLLPGGALDTARLTPAERDQLALHGLDDRQRHQLGAAADGRRAREKVAARASGAAGPPLPLSAVVTTDSRPWFWSGAQGLEPSALVGDVRRGVRLRIRYRRAAESAPAWQLVDPYGLLAKAGRWYLVADRSGTPRLYSLERLTDWRPTAAPRRLRPGISLADAVAELTTGWETSADLRIHGLLAARHAERARRILGSRVTVHRPGEGPALSPSPGPDQVALTLSCRNLEEARQLLPFGADLLITDPPEARTRLRELAAEVVGQYAEQDEGDEGAGPTYPRPS
>NC_020990.1|WP_003949015.1|3797063_3797423_+|glyoxalase
MTRPNMFIVHVSDAPESARFYGDLFAMEPVFEAPRFIAFELGGGVQLALWSGAAEDLSGPRTSEVCLNLDGAPASVDARHEEWTAKGVTIVEEPHDAVFGRTFVAADPDGNLIRVAPFD
>NC_020990.1|WP_003949014.1|3797440_3798112_-|haloacid-dehalogenase-type-II
MSRRPDPQFVTFDMYGTLTDFPVGAAAEKTIEAISSPGQRDVFRRRFAAYQLDESMGDWRPYDELIARAFERACRSAGIPFRPADPAAVFDQIPTWGPHPDVPGPLARLAARHPLVILSNASDQHASRNAALLGAPLHAVYTAEQARAYKPRLGAFEYLYAQLGCRPEDTLHVSASPRYDLQSATDLGVRETVYLNRGYEPSAPHCHAYEVTTLAGVAELLGV
>NC_020990.1|WP_003949013.1|3798339_3799779_+|rifampin-monooxygenase
MIDVLVVGAGPTGLMLAAELRLHGVRTVVVEKDTEPTGHSRAQGLHVRSTELMDQRGLLDQFLARGRQFRVGGFFAGLGPAWPEGMDTAHSYVLAIPQAETERLLAEHATGLGAEFRRGCALTGLEQDADGVTAGLADGTRLRARYLVGCDGGRSTVRKLLGTPFPGEPSRVDTLLGDVALTATPEELAAVTAEVRKTHLRYGAMPLGEGRYRVIVPDEGASEDRAAPPTLDHLRARLRAVGGTDFGAHDPRWISRFGDATRQAERYRTGRVLLAGDAAHVHPPTGGQGLNLGVQDAFNLGWKLAAEVNGWAPDGLLDSYHAERHPVGAAVLDNTRAQTELMNPGPGQRALRRLVAELMEFEEVNRHLIEKITAVSVRYDLGGGHPLVGRRLRDVRLGRGRLYELTHAGRGLLLDPAGRLSAGGWADRVDHVVDTGPELDELDVPAALLRPDGHVAWVGDDQEGLAPALKRWFGEPAAG
>NC_020990.1|WP_008415428.1|3799809_3800664_-|alpha/beta-fold-hydrolase
MPLSPTFVLVHGAFANSFSFAPLQAELGLLGHRSVAVDLPGHGFEATFPASYQAPQDFAALAAEPGAIKGVTLADNAARVIEALERARRNGPTVLVGHSRGGATITAVANARPDLIDRLVYVSAWCPVDLPVGDYYAEPEMASVDPMAFAPSLLGNPAELGLLRTNFRTSDPAALATFKEAFGADLTDDEFRTFLNTFQPDESLDAGTEADRAQAATWGTLPRTYVRLADDTSLTPAAQDRMIREADALTPGNPFDVHTLDGSHLRWLVHPGPAAAVLAGLAAG
>NC_020990.1|WP_003949011.1|3800758_3801517_+|class-I-SAM-dependent-methyltransferase
MADECFRHPRLAAVYDALDPDRSDLDAYVRAAREFGARRVLDIGCGTGVFALLLAARGIEVVGVDPARASLDVARAKPGADRVRWICGDATGLPPLRADLATLTANAAQEITGPDAWRATLRGAYGALRPGGHLLFETRDPARRAWEEWTPEASRHTTEIPGHGAVESWVELREVRGPLVTFRWTYVFAADGQVLTSDSTLRFRERQEVEADLAAEGFEVVEVRDAPDRPGKEFVFVARRGEGTGAGAGSVA
>NC_020990.1|WP_003949010.1|3801632_3802271_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MTDPVWASIHAERAALAADLAGLTEEQWATPSLCSGLTVREVLAHLTASASLNAVRWMAGVIRCRFDFDRQVAVRLAEQLGATPAETLERFRSVVASTTKPPLPVVALLGETLVHGEDIRRPLGLRRDHPVEVVTRVAAYYQGSDQVVVARSRVAGLRLVADDGPFTSGTGPLVSGSTLALVMAMTGRTACCDDLDGEGVELLRSRCGAGAA
>NC_020990.1|WP_015507636.1|3802287_3803085_-|hypothetical-protein
MSLSGLSLSRWRSLDPPAARRLARQAADRAGGQVTAVETVEHLGAPLHRVRIACRGREFALIPGGEVTLGFDADGRRLPPGLEAGYAESAEQGYGYGPDLRSHLAQVLSPRRTVTVPAVLMAVEAEKLTAPPAGTPGRLAAEGLRMPSSDEWEHACGAGADTLFRWGDTCPLDRIPYGDDSGPHQQPNAFGLRIAHDTYDAELTSWPGAVHGGDGGESVCGGYGAVLAWLPLATAQRNPAMAEFVYGPDGEEMYEEFSTRPVLAL

Crispr_ID: NC_020990_21

• CRISPR_ID: NC_020990_21
• CRISPR_location: 3849171-3849258
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_21

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCTGT	CRISPRCasFinder

spacers of NC_020990_21

>21.1|3849196|38|NC_020990|CRISPRCasFinder
TGGTTGCCGGGCTCCGTCTCGACCGTGCCGGTCACCGA

CRISPR arrays and Neighbor proteins around NC_020990_21

CRISPR arrays

The CRISPR arrays of NC_020990_21

>merge|NC_020990|21|3849171-3849258|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGTTGGTTGCCGGGCTCCGTCTCGACCGTGCCGGTCACCGATGGCCTCAATCGCCGGCCGGGCTGT

>NC_020990|21|16|3849171-3849258|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGT	TGGTTGCCGGGCTCCGTCTCGACCGTGCCGGTCACCGA
TGGCCTCAATCGCCGGCCGGGCTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003948970.1|3848150_3849083_+|M56-family-metallopeptidase	unknown	unknown	gnl|CDD|320685
NC_020990.1|WP_008405903.1|3845929_3846313_-|N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_020990.1|WP_003948978.1|3840343_3841369_-|amidohydrolase	unknown	unknown	gnl|CDD|368185
NC_020990.1|WP_003948976.1|3842743_3843406_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NC_020990.1|WP_003948979.1|3839628_3840312_-|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase	unknown	unknown	gnl|CDD|181735
NC_020990.1|WP_015507647.1|3844237_3845785_-|MFS-transporter	unknown	unknown	gnl|CDD|184957
NC_020990.1|WP_015507653.1|3864517_3864997_-|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NC_020990.1|WP_003948965.1|3855303_3856560_+|arsenic-transporter	unknown	unknown	gnl|CDD|238538
NC_020990.1|WP_015507648.1|3846697_3847381_-|hypothetical-protein	unknown	unknown	gnl|CDD|374404
NC_020990.1|WP_003948959.1|3863339_3863858_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948961.1|3859700_3860948_+|DUF2786-domain-containing-protein	unknown	unknown	gnl|CDD|378525
NC_020990.1|WP_003948969.1|3849954_3851643_-|bifunctional-3'-5'-exonuclease/DNA-polymerase	unknown	unknown	gnl|CDD|237876
NC_020990.1|WP_015507652.1|3861055_3863335_+|FUSC-family-protein	unknown	unknown	gnl|CDD|130728
NC_020990.1|WP_003948958.1|3864224_3864467_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NC_020990.1|WP_015507651.1|3858160_3859420_-|hypothetical-protein	unknown	unknown	gnl|CDD|224001
NC_020990.1|WP_033240634.1|3843473_3844208_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_020990.1|WP_003948971.1|3847753_3848149_+|hypothetical-protein	unknown	unknown	gnl|CDD|367747
NC_020990.1|WP_003948964.1|3856605_3857781_-|winged-helix-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|377630
NC_020990.1|WP_003948977.1|3841365_3842553_-|4-oxalomesaconate-tautomerase	unknown	unknown	gnl|CDD|380230
NC_020990.1|WP_003948968.1|3851771_3852953_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003948970.1|3848150_3849083_+|M56-family-metallopeptidase	gnl|CDD|320685	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	6.26596e-24
NC_020990.1|WP_008405903.1|3845929_3846313_-|N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	0.00973474
NC_020990.1|WP_003948978.1|3840343_3841369_-|amidohydrolase	gnl|CDD|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	3.04869e-51
NC_020990.1|WP_003948976.1|3842743_3843406_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	6.003e-40
NC_020990.1|WP_003948979.1|3839628_3840312_-|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase	gnl|CDD|181735	PRK09262, PRK09262, hypothetical protein; Provisional.	1.13659e-138
NC_020990.1|WP_015507647.1|3844237_3845785_-|MFS-transporter	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	9.91913e-84
NC_020990.1|WP_015507653.1|3864517_3864997_-|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	6.69392e-24
NC_020990.1|WP_003948965.1|3855303_3856560_+|arsenic-transporter	gnl|CDD|238538	cd01118, ArsB_permease, Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.	2.82254e-97
NC_020990.1|WP_015507648.1|3846697_3847381_-|hypothetical-protein	gnl|CDD|374404	pfam16165, Ferlin_C, Ferlin C-terminus. This domain is found at the C-terminus of proteins belonging to the ferlin family, including dysferlin, myoferlin, otoferlin and fer-1-like proteins.	0.00023255
NC_020990.1|WP_003948961.1|3859700_3860948_+|DUF2786-domain-containing-protein	gnl|CDD|378525	pfam10979, DUF2786, Protein of unknown function (DUF2786). This family of proteins has no known function.	1.67737e-11
NC_020990.1|WP_003948969.1|3849954_3851643_-|bifunctional-3'-5'-exonuclease/DNA-polymerase	gnl|CDD|237876	PRK14975, PRK14975, bifunctional 3'-5' exonuclease/DNA polymerase; Provisional.	0
NC_020990.1|WP_015507652.1|3861055_3863335_+|FUSC-family-protein	gnl|CDD|130728	TIGR01667, Uncharacterized_protein_HI_1680, integral membrane protein, YccS/YhfK family. This model represents two clades of putative transmembrane proteins including the E. coli YccS and YhfK proteins. The YccS hypothetical equivalog (TIGR01666) is found in beta and gamma proteobacteria, while the smaller YhfK group is only found in E. coli, Salmonella and Yersinia. TMHMM on the 19 hits to this model shows a consensus of 11 transmembrane helices separated into two clusters, an N-terminal cluster of 6 and a central cluster of 5. This would indicate two non-membrane domains one on each side of the membrane.	6.58012e-23
NC_020990.1|WP_003948958.1|3864224_3864467_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	3.57873e-18
NC_020990.1|WP_015507651.1|3858160_3859420_-|hypothetical-protein	gnl|CDD|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	0.000302534
NC_020990.1|WP_033240634.1|3843473_3844208_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	4.28372e-19
NC_020990.1|WP_003948971.1|3847753_3848149_+|hypothetical-protein	gnl|CDD|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	6.89103e-25
NC_020990.1|WP_003948964.1|3856605_3857781_-|winged-helix-DNA-binding-domain-containing-protein	gnl|CDD|377630	pfam06224, HTH_42, Winged helix DNA-binding domain. This family contains two copies of a winged helix domain.	1.98543e-51
NC_020990.1|WP_003948977.1|3841365_3842553_-|4-oxalomesaconate-tautomerase	gnl|CDD|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
NC_020990.1|WP_003948968.1|3851771_3852953_+|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	3.51796e-36

Protein sequences

>NC_020990.1|WP_003948970.1|3848150_3849083_+|M56-family-metallopeptidase
MGLFVFLPLILPLTAHPIARLAEQHLHPRTGTRLLAGLSLVLAVCSTLCLALLVVAGTARLPGNPLPDAWAAPEVRAVVPYDEVTGSAALIALLAALTACALALVREARLRLRTRRALAGLPGTHPAVLPDPEPYAYALPGRPGRIVVSRAMLESLDADERHALLAHEQAHLDGRHHRLLLAVRLAACLNPLLRPLRSAVGYGAERWADEDAAMAVGDRRLTARAVGRAALSSRSGPAFGLAFAEPAPGPVPRRVAALLGPAPSPRRLPPAMTRPGLAFLMATTGAAASAASSVNAALTLLLVLKAATPL
>NC_020990.1|WP_003948971.1|3847753_3848149_+|hypothetical-protein
MAEVNAQGGRRRGQGELEAQVLAVLHTADEPVSAAWVRERLGGDLAYTTVMTILSRLGAKNAVTRERSGRAFLWTAAADEAGLAALRMRRVLDGERDRDAVLTSFVSSLSGDDERLLRALLESARGDTDGG
>NC_020990.1|WP_015507648.1|3846697_3847381_-|hypothetical-protein
MRTRLANRSARLLLAAAAATALAATTTACGPEDNGAAAPAASASTSTDASADASDGAESGTGGTDSGSEDSGSEAGAGADKGGDKGAGEGGVGQSCGTNDLDLTLTPKSQAGGYYQVTAKAKSGITCYLDVNTPSVAFGSKPEGVASPVGQGGEDPIKLSGSAVAYTGISPKTTKEDGGVEFENVIVSVTDEDPNPAELALPEPAAVEKPIVTNWSTNPGETIPVIV
>NC_020990.1|WP_008405903.1|3845929_3846313_-|N-acetyltransferase
MTRHPRSTRPESGTAPAFHATSAGRPAGPRELLIRDAADREIGRIEFRLCRACGTGHVDSVTVAPSWQGQGLAREALHRILPDDLALTWTTSRQTGQGRAFFAAVTEETGIDFPAGRPGCAHLREPG
>NC_020990.1|WP_015507647.1|3844237_3845785_-|MFS-transporter
MTAPASSAASRDRGPALSRGRRWAATGALAASLLVVAMDMTVLNIALPALTAELRPTSVQLLWIVDVYSLVLAGLLVPCAALADRWGRRRTLLLGYGLFAGASLLVPAADAAPGVIAVRALLGVGGAMILPTTLSMIRVLFTDPAERATALGVWAAVSGLGAAAGPLVGGFLLQHFPWQAAFLVNVPLILVALVAGLALLPESRVAEPGRWDARAAVLALAGMVLLVWSVKRFGEGNGPTAPEAWAALAGAGVALTWFARRCLGRADPLLELRLFGRRPFTAGIVAALGTTFSMVGAMLLLAQWLQLADGASPMAAGVRLLPVATAGVAASLLAPPLARLLGARTVLAAGPAVTGTGLLVLALTPGPLALPAVLTALTLIGAGTGSLAVGSALIMSSAPEEQAGSAGALEETSYELGAALGVAVLGTVAGQVYRARLADTPALHDAPPGLAAQAAESLGGAVGVADRLAQPRLAEQAATAFTEALRTAGLVGAVLMFAVAATVFALAPGRRSASD
>NC_020990.1|WP_033240634.1|3843473_3844208_-|class-I-SAM-dependent-methyltransferase
MAARPARRADSTTVPRMTAPDATPDALTDSLTATRTAYDAAADTYAQLFRDSLREAPLDRAMLAAFAEAVRGAGPDARVADLGCGPGHVTAHLAGLGLVPRGFDVSPAMIGLARAAHPELRFDVGSMAGLDLPDATLSGVLSRWSVIHTPPAELPPVLAEFARVLAPGGQLLLGFWASESPGHRTQVFDHAVAPAYRWCPDHLSALLREAGLTETARMIREPQPTDRRQFRQVHLLAHRADVTA
>NC_020990.1|WP_003948976.1|3842743_3843406_+|GntR-family-transcriptional-regulator
MTDKLTGAAARQHVADSIRHALRSGDLVPGQRLVENDLAAAYGATRGAVREALQDLAAEEILEIVPRRGARVRTVSVEEAVQITECRSALEQLCAGKAATLATDDQRAELARIGVDMRQAVADGAWEAYSALNQRLHELVIEASGQEVARRTLGRLNGPMVRYQFRLALRPGRPARSLPQHLAIIEAVVGRDPEAAGRAAAAHLDDVIEQLRSSAAPSPT
>NC_020990.1|WP_003948977.1|3841365_3842553_-|4-oxalomesaconate-tautomerase
MPAVAASPAPEVTRRGSQTAVPCLFMRGGTSRGPFFDARLLPEDPGLRDAVLLAAMGSPDARQIDGVGGGHPLTSKIGLVRPASAAGADLEWTFAQVQPDGRTVDTSSNCGNMLAAVVPFALETGMITAAGDRTTARVLTLNTGMVAEITVATPADRAGTRHVAYEGAARVDGVPGTASPVEIGFLDTAGSVTGSLLPTGRTRDTLDVPGLGPVDVTLIDNGQPLAIVAAGRLGATGYESPSEIDADEELRDRVEALRLVCGEAMGLGDVSARNYPKMTLVAPARHGGTLSTRSLIPRVCHQSIGVLAAVTAATACVLDGSVAHELATAVRGTDPTVSVEHPSGSFDVTLARDAADPRRVTRSALLRTARLLMAGDVLVPRSVWDPAPTAQENSA
>NC_020990.1|WP_003948978.1|3840343_3841369_-|amidohydrolase
MIIDIHGHYTTAPAPLGHWREAQAAALTDPVRAPDPAGPVISDDQIRESLETNQLRLMDERGIDVTVFSPRASFMAHHIGDFATSAAWSRICNDLCHRVSELYPDRFAPGAMLPQSPGADPATTIPEIERAVRELGAVTVNLSPDPSGGHWTAPPLSDRSWYPVWEKLVELDVPAMVHVSSSCNPAFHTTGAHYLNADTTAFMQLLDSDLFADFPELRLVIPHGGGAVPYHWGRFRGLAQALGRPEPEDGLLRNVHFDTCVYHQPGIDLLLEVIPAANVLFASEMVGAVRGVDPRTGHHFDDTRRYVERANLSPADLAAVLEGNARRVYPLLDARLTAQGR
>NC_020990.1|WP_003948979.1|3839628_3840312_-|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase
MHPLGIVHRTVERADRAAVEALSAFGVATVHEAMGRLGLMRPYIRPVYEGARLCGTAVTVLLQPGDNWMLHVAAEQVREGDVVVAGCTTESEDGFFGELLATSLRARGASGLVIDGGCRDVDDLRRMDFPVFSRAVNAKGTVKATLGSVNVPVVVANALVNPGDVVVADADGVVVVPAARAAEVAEAAARREAAEEGKRQRFRDGELGLDLYAMRGPLAELGLTYLD
>NC_020990.1|WP_003948969.1|3849954_3851643_-|bifunctional-3'-5'-exonuclease/DNA-polymerase
MAERWAVAVTEGGGAEVAPLAADGTLAGPVVREAALAEAVRSRPGVSRWVWRATAGIYPQLLRAGVRTERCYDVEAAETLLLGHEGRLGAPHSAAAALARLRGTPVPPDPPPRAAEPGAGAQSSLFEPQPVPVGLADLAEVYAEQLRRHENAVHPGRMRLLTASESAGALVAAEMTAAGLPWRAETHREVLRELLGERYGGSGEPRRLAELADEVSAAFGHRVRPELPAEVVRAFARAGIKVTSTRRWELEKIDHPAVAPLLAHKKLYRIWVAHGWQWLADWVRDGRFRPSYLPGGTVSGRWATNGGGALQIPKVIRRAVVADPGWRLVVADADQLEPRILAAVSGDRALMEVASRPDDLYQAVSDRAFQGDRDLAKLAVLGAVYGQTSGDGLKNLAALRRRFPAAVDHVDEAARAGEEGRLVRTWLGRTCPPATAPGGPAEEAGIPDALPEGDTGGYAPGASSGARARGRFTRNFVVQGSAADWALLLLAALRSSLAPLRAELVFFQHDEVIVHCPDEEAPAVVAAIAAASDRATAICFGDVPVRFPFTTAVVGCYAEAKG
>NC_020990.1|WP_003948968.1|3851771_3852953_+|serine/threonine-protein-phosphatase
MARERIGAAALLAAAERAAPVDSLDVVARDLRDGLGAWNVSFLFLDAVGRKMVRVTEETAAGQADRIERLPLDGTLYDEVLRGQRLRKLPDGPGGTRVLAPVTNRGDTLGVLELFLPGEVTAQVRERIEGAAHVLAYILVTDRRFTDLYHWGQRTTTVSLAAEIQRQLLPASSCCEADAFTLAAALVPADNIAGDTYDFALDRDTLHVSVTDAMGHDVAASLMATLLVSASRGARRAGVDLAEQARRTHQALLDHGSGTFATGLLFRLALDGSGAQFVNAGHHWPLRLREGRVEEVHPEVDLPFGVPEADAHRVQELDVRPGDRLVLYTDGMRERRAEIVDLSALVLATADDHPRQVVHTLTAAVDEACGGRLADDATVLCLDWYGPAGDRAA
>NC_020990.1|WP_003948965.1|3855303_3856560_+|arsenic-transporter
MNAHPAEAVSVVLLLLVLAGAVFRPWGRSEALVAVPAAGTVIAVGALSLDHAAAEAARLGPVIGFLAAVLVLAHLCEREGLFRACGAWMADRAAGSPRRLLVLVFVTASLITAVLSLDATVVLLTPTVFATAARLGVRAGPHLYACAHLANSASLLLPVSNLTNLLAFAASGLTFTRFAALMALPWLVAIGTEYLVIRWFFAGELAAGGRAPDLGRPRELPLSALLTVAATLAGFVVLSAFGAQPVWAAVAGAAVLAVPALARGRTSVRELVQAAALPFCLFVLALGMVVRAVVDNGLGAALGHLLPDGTGLLALFLLAALAAVLANLINNLPAVLVLLPLTAPAHPGAVLAVLLGVNIGPNLTYTGSLATLLWRRVVRGHGTDVRLGEFTRLGLVSVPLVLSLSVLALWVSLRTVGS
>NC_020990.1|WP_003948964.1|3856605_3857781_-|winged-helix-DNA-binding-domain-containing-protein
MPLTPRELNRATLARQLLLERSPLSVPDGVRQVVALQAQHPASPYVALWNRLGGFDPAGLDAAFAGRTVVKATLMRITLHAVHAEDYGPFRAAMQPTLYGARLGARFAGTGLTPADAARLLPGLLEFARTPRTSAELRAWVEAEVGAERRDGAWWGLKGYAPLHHAPTEPPWTFGHRPSFVAAGLDAPPTRADGDPHVQEALRTLILRYLSGFGPASVADVAQFALVRRTAVRQALAALGEAVVHLPGPDGTPYHDLPDAPRPDGGTPAPPRLLGMWDSILLAYADRARVIPPAYRPLVIRRNGDVLPTLLVDGEVAGVWRPVGDEDGAGDGNRAGIEATAFHPLSPATWDALAAEARSLTALLTARDTTAYRRYGHWWAKLPEGGEVRRL
>NC_020990.1|WP_015507651.1|3858160_3859420_-|hypothetical-protein
MSEQSAEQSEQAVGTIGLMRPLDAAVPPAAPAPDETWTFGRVLKEDADGNPVHEATAWVYHGEGNSGLVRPVLLADGFNSGHSSLDGLYDGLERGAYPLLGELRRSGRDVIILGWGDRSASVLANARFASEAILRTIAQRLGGERLVVGGFSMGGLVTRYALARLEHQRIDHQTGVYFSWDTPHRGAWVPIGLQAFAHYLKQLNPYNRALSDQINSPAAKQMLWRHLDSVQASAEVTTEREEFLAELERVGGWPRIPRLLAVANGRGDGSGNGAEAGVPALRSTGPAFPRTVLRTQQEGAGTVVAELRAVLGRDETVTTDDLPEFDGAPGGTLSSFAIAAAALNALPLASAEAPVPSVCFVPTVSAVSIRDLDTTELLRTDIDKTPPDESDFDDFLCASENEPHTKITEELGSWLLDRF
>NC_020990.1|WP_003948961.1|3859700_3860948_+|DUF2786-domain-containing-protein
MGGSGRSGGGARDGGRGGAGPETPVARALAAALYGGADDDAALDTGASLLAAADPDEAGRELLLRGEEYVRRAWERGWLPADLDREARRQELDPAARTALAELTAAELARYGNGLTPLWRRQLDALAAPAWAGTGGRDRFARATAVLQALRLLLRLPALEPLGPPPGGRPAGAAAAPRTPGGEAPEDRMLGRIRALLAKAEATGYPPEAEALTAKAQELMARHSVDEAQLSAGRAGGADAPGARRISVDPPYETAKAILLDAVARANRCQAVWNEELAFSTVVGHEADLEPAELLYTSLLVQAATAMSRAEAAQRAGGRKRTKTFRQSFMLAYAHRLGDRLAETARAATETLAAADLLPVLAGRDLAVTEETRRLFPRTTTTRVRGADDRAGWDDGTRAADRAGVDGHRGRIDQG
>NC_020990.1|WP_015507652.1|3861055_3863335_+|FUSC-family-protein
MSWLSALGHTARAGFAVERRRLEPLSALRGALGLAFVIGVSLWLFSPAVAASSAFGAYQAAIATFQRSWRPRPQLALVSGATLGISTFLGYLSASHLALFLALLATWAFLSGLSWAAGPTVGVMASSNVAIMLITITLPSSVAEAAGHAAMSLFGGLVQAALLVLFPFRRWRPHRDALADALAAEADYARRLRHDPHADFDPEPLMEAREAAQLTPREHRHRPAELSGARGLAERIRPVLASLADPALGAPAEGVERDRVRELLAAAAAVLDAAARSVRRGTPLALDAPSVATLRTPDTGDVLTGPARRSALRLKALLGDVIETADPAGRSTAAPDAPPQAAARADAVREEATRATLARTQEPGAPQEPSAPGAHAAPPPPDEPPLPVEPAEPPAPAVLHRPGLISLVPVVARSMRAELRPDSAILRHAIRVTAVALLGYLIGTLLPFGHGYWAPLAAVMVMRPDFSRTYSRAVARFGGTLLGVFAATGILQLTEPSVRVSALLAVACAALMYLLMRTGYAVSQFFVSGYVVFLLGMGGEEWTQTVPERVVLTLIGGVLAMASYALFPAWETPRLRTRLADWLTAAGRYAAEVVERYATPAGPDDTRVRTALLEARAAHTAWQEALARAAHEPVRNRGLSRTSADDAEEAIGAFSRAAMLMEAHLPERGAVPVPAAQRLAHALRTTTERGARDLRDRRVPQWDEVRAALAAWDGEGVPDRVVRRGAGMLLAALEQVSEAAEESPPFAESRAERAAGEGP
>NC_020990.1|WP_003948959.1|3863339_3863858_-|hypothetical-protein
MRKLVRISVAASAAALLLLTGCGSDSDSSGGGTGKHKGGSHGSDADGDGGTGGSGGASSAPGSAEGAWHATVDGASLFLTITGNQAATIGKGSCAGTYQAQKLSLKCADGSTDRTSGKAELSGDGDSLTVSWEGSGEESFRRVDPGTLPQELPTDLPTELPSGVPTGDVTTQ
>NC_020990.1|WP_003948958.1|3864224_3864467_+|DUF397-domain-containing-protein
MHHVYNGMAASELHDVAWQKSRHSNSQGSCVEFAKLPGGGVAVRNSRHPEGPALVYTRAEIEAMLLGIKDGEFDHLIAGA
>NC_020990.1|WP_015507653.1|3864517_3864997_-|ATP-binding-protein
MGTNGSTMLAPLRQGLPPLDPAHVRYAASCALPPRYEAVRSARAFTRRTLAEWKNDERFDDIALVVSELVTNALRHALPADTPRPDDPPVRLHLTACERRLVCAVRDPSEGTPAARPPGDCDAESGRGLFLVDSFSDAWGWHPLAGQLDGKVVWALFEV

Crispr_ID: NC_020990_22

• CRISPR_ID: NC_020990_22
• CRISPR_location: 4149201-4149302
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_22

Consensus_repeat	Method
TGGCCTCAGGCGCCGGCCGGGCTGT	CRISPRCasFinder

spacers of NC_020990_22

>22.1|4149226|52|NC_020990|CRISPRCasFinder
TGGTAGCCGGGCTCCGCCCCGACCTGCCGACCGTGACCGTGCCGGTCAAAGA

CRISPR arrays and Neighbor proteins around NC_020990_22

CRISPR arrays

The CRISPR arrays of NC_020990_22

>merge|NC_020990|22|4149201-4149302|CRISPRCasFinder
TGGCCTCAGGCGCCGGCCGGGCTGTTGGTAGCCGGGCTCCGCCCCGACCTGCCGACCGTGACCGTGCCGGTCAAAGATGGCCTCAAGCGCCGGCCGGGCTGT

>NC_020990|22|17|4149201-4149302|CRISPRCasFinder
TGGCCTCAGGCGCCGGCCGGGCTGT	TGGTAGCCGGGCTCCGCCCCGACCTGCCGACCGTGACCGTGCCGGTCAAAGA
TGGCCTCAAGCGCCGGCCGGGCTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003948731.1|4158877_4161406_+|NADH-quinone-oxidoreductase-subunit-G	unknown	unknown	gnl|CDD|236118
NC_020990.1|WP_003948739.1|4150520_4151807_+|geranylgeranyl-reductase-family-protein	unknown	unknown	gnl|CDD|273936
NC_020990.1|WP_003948743.1|4146536_4147736_+|dehypoxanthine-futalosine-cyclase	unknown	unknown	gnl|CDD|274731
NC_020990.1|WP_003948748.1|4139148_4139610_+|membrane-protein	unknown	unknown	gnl|CDD|227296
NC_020990.1|WP_003948740.1|4149911_4150418_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NC_020990.1|WP_003948736.1|4153974_4154529_+|NADH-quinone-oxidoreductase-subunit-B	unknown	unknown	gnl|CDD|235797
NC_020990.1|WP_003948741.1|4148450_4149146_+|demethylmenaquinone-methyltransferase	unknown	unknown	gnl|CDD|234689
NC_020990.1|WP_003948732.1|4157531_4158881_+|NADH-quinone-oxidoreductase-subunit-NuoF	unknown	unknown	gnl|CDD|131014
NC_020990.1|WP_018468570.1|4151904_4152693_-|C40-family-peptidase	unknown	unknown	gnl|CDD|366353
NC_020990.1|WP_030772685.1|4156695_4157532_+|NADH-quinone-oxidoreductase-subunit-NuoE	unknown	unknown	gnl|CDD|181024
NC_020990.1|WP_008415882.1|4144973_4145702_+|prepilin-peptidase	unknown	unknown	gnl|CDD|224900
NC_020990.1|WP_003948735.1|4154525_4155281_+|NADH-quinone-oxidoreductase-subunit-C	unknown	unknown	gnl|CDD|181115
NC_020990.1|WP_015507699.1|4147750_4148383_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948737.1|4153563_4153923_+|NADH-quinone-oxidoreductase-subunit-A	unknown	unknown	gnl|CDD|181171
NC_020990.1|WP_008415881.1|4142037_4144977_+|membrane-protein	unknown	unknown	gnl|CDD|198111
NC_020990.1|WP_030773820.1|4140397_4141531_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948744.1|4145834_4146494_+|flavin-reductase-family-protein	unknown	unknown	gnl|CDD|224766
NC_020990.1|WP_030773817.1|4139693_4140308_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_008415873.1|4138672_4139152_+|TadE-like-protein	unknown	unknown	gnl|CDD|377921
NC_020990.1|WP_015507701.1|4155280_4156660_+|NADH-quinone-oxidoreductase-subunit-D	unknown	unknown	gnl|CDD|180385

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003948731.1|4158877_4161406_+|NADH-quinone-oxidoreductase-subunit-G	gnl|CDD|236118	PRK07860, PRK07860, NADH dehydrogenase subunit G; Validated.	0
NC_020990.1|WP_003948739.1|4150520_4151807_+|geranylgeranyl-reductase-family-protein	gnl|CDD|273936	TIGR02032, Uncharacterized_protein_MJ1520, geranylgeranyl reductase family. This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll].	9.4882e-102
NC_020990.1|WP_003948743.1|4146536_4147736_+|dehypoxanthine-futalosine-cyclase	gnl|CDD|274731	TIGR03699, menaquin_MqnC, dehypoxanthine futalosine cyclase. members of this protein family are involved in menaquinone biosynthesis by an alternate pathway via futalosine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	0
NC_020990.1|WP_008415881.1|4142037_4144977_+|membrane-protein	gnl|CDD|198111	smart01043, BTAD, Bacterial transcriptional activator domain. Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.	5.88048e-09
NC_020990.1|WP_003948740.1|4149911_4150418_-|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.18473e-22
NC_020990.1|WP_003948735.1|4154525_4155281_+|NADH-quinone-oxidoreductase-subunit-C	gnl|CDD|181115	PRK07785, PRK07785, NADH dehydrogenase subunit C; Provisional.	4.67402e-154
NC_020990.1|WP_003948741.1|4148450_4149146_+|demethylmenaquinone-methyltransferase	gnl|CDD|234689	PRK00216, ubiE, bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE.	1.68769e-128
NC_020990.1|WP_003948732.1|4157531_4158881_+|NADH-quinone-oxidoreductase-subunit-NuoF	gnl|CDD|131014	TIGR01959, NADH-quinone_oxidoreductase_subunit_F, NADH-quinone oxidoreductase, F subunit. This model describes the F chain of complexes that resemble NADH-quinone oxidoreductases. The electron acceptor is a quinone, ubiquinone, in mitochondria and most bacteria, including Escherichia coli, where the recommended gene symbol is nuoF. This family does not have any members in chloroplast or cyanobacteria, where the quinone may be plastoquinone and NADH may be replaced by NADPH, nor in Methanosarcina, where NADH is replaced by F420H2. [Energy metabolism, Electron transport].	0
NC_020990.1|WP_018468570.1|4151904_4152693_-|C40-family-peptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	2.9911e-28
NC_020990.1|WP_030772685.1|4156695_4157532_+|NADH-quinone-oxidoreductase-subunit-NuoE	gnl|CDD|181024	PRK07539, PRK07539, NADH-quinone oxidoreductase subunit NuoE.	8.21571e-88
NC_020990.1|WP_008415882.1|4144973_4145702_+|prepilin-peptidase	gnl|CDD|224900	COG1989, PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	2.0505e-09
NC_020990.1|WP_003948736.1|4153974_4154529_+|NADH-quinone-oxidoreductase-subunit-B	gnl|CDD|235797	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB.	6.5693e-102
NC_020990.1|WP_003948737.1|4153563_4153923_+|NADH-quinone-oxidoreductase-subunit-A	gnl|CDD|181171	PRK07928, PRK07928, NADH dehydrogenase subunit A; Validated.	4.73227e-78
NC_020990.1|WP_003948748.1|4139148_4139610_+|membrane-protein	gnl|CDD|227296	COG4961, TadG, Flp pilus assembly protein TadG [Intracellular trafficking and secretion].	0.00203561
NC_020990.1|WP_008415873.1|4138672_4139152_+|TadE-like-protein	gnl|CDD|377921	pfam07811, TadE, TadE-like protein. The members of this family are similar to a region of the protein product of the bacterial tadE locus. In various bacterial species, the tad locus is closely linked to flp-like genes, which encode proteins required for the production of pili involved in adherence to surfaces. It is thought that the tad loci encode proteins that act to assemble or export an Flp pilus in various bacteria. All tad loci but TadA have putative transmembrane regions, and in fact the region in question is this family has a high proportion of hydrophobic amino acid residues.	5.22132e-06
NC_020990.1|WP_003948744.1|4145834_4146494_+|flavin-reductase-family-protein	gnl|CDD|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	8.89664e-28
NC_020990.1|WP_015507701.1|4155280_4156660_+|NADH-quinone-oxidoreductase-subunit-D	gnl|CDD|180385	PRK06075, PRK06075, NADH-quinone oxidoreductase subunit D.	0

Protein sequences

>NC_020990.1|WP_003948741.1|4148450_4149146_+|demethylmenaquinone-methyltransferase
MTRASLDKQPQEVASMFDDVAAHYDLTNDVLSLGQARLWRKEVARAVDARPAQKILDLAAGTATSSQPFARAGAYVVPCDFSLGMLQVGKGRHPWMPFTAGDAMRLPFRDDTFDAVTISFGLRNVQDTSAALAELYRVTKPGGRVVICEFSQPTWAPFRSVYTEYLMRALPPVARAVSSNPDAYVYLAESIRAWPDQPALAGLLQEAGWGRVAWRDLTGGIVALHRGYKAP
>NC_020990.1|WP_015507699.1|4147750_4148383_+|hypothetical-protein
MLTLHTAPLLLPPGAAPLPDGAVLVQGEAVLAVGPRADLAAAHPGARVRAWPGLLTTGLTHARAVPLLEAAYHPDPREYDQLGEAPLTGEALARLAPDRTRRSGSVRRGLQRLLRHGVTRVAGTFTDPAVRPALARSGVSVVPGPASAPGPVSFDPFTGGHDALSGVPLAPGVRADLAAFDVPDAAALRDGGAAACVATVLAGRLVHRAR
>NC_020990.1|WP_003948743.1|4146536_4147736_+|dehypoxanthine-futalosine-cyclase
MTEKADLQSVLDRAAAGGRITPEEAVALYRDAPLHALGTAADAVRRRRYAGTEHIATYIIERNINYTNVCVTACRFCAFYAAPKDTAKGWTRDLDDILRRCAETIELGGTQIMFQGGHHPDFGVEYYEKHFAAIKKEFPELVIHSLGASEVEHMARISKTTVEDAIERIHAAGLDSFAGAGAELLPVRPRKAIAPLKESGERWLEIMETAHRLGVESTSTMLMGTGETNAERIEHLRMIRDSQDRTGGFRAFIPYTYQPENNHLKGRTQATLFEYLRMIAIARLFLDNVAHIQGSWLTTGKEVGQLSLHYGADDLGSIMLEENVVSSAGAKHRSNRLEIIDLIRKAGRVPAQRATTYEHLVVHDDPANDPVDDRVASHISSIAIDGGTAHPELKLLAPN
>NC_020990.1|WP_003948744.1|4145834_4146494_+|flavin-reductase-family-protein
MHVVPGLKVLYFGTPVVLVGTRNEDGTANLAPISSAWWLGRYAMLGLGDVARTTANLLREGECVLSLPSPALADAVDRLALTTGRPDVPERKARQGYRYEPEKFAAAHLTEQPGELVRAPRVAECPIQLECRVVASHPFGGPGMHATAFQVEVVRTHVEEGLVIPGTHHVDPDGWDPLIMKFCEFYGGGHRLRSSRLADGWEMPHQRPGGERTTQNRRA
>NC_020990.1|WP_008415882.1|4144973_4145702_+|prepilin-peptidase
MTGPLWLAPLAALWGAGWGALLPRAAYRFAAPAGEEWHTACPQGHPLGGWLGGPNCPDCRTPLGRRALPVLLAAALCAGLALTTGPRPELAVWLLAAPVGLLLAVVDLRVMRLPDPLTLPLAAGVLALLGVAAALPGAAGSWLGALYGLLALGGGAFVLFLINPDGFAFGDVKLCLALGAALGWYGLGAVFLGAFAGLLVGAVHGLFLVLAKGAGRRTAFAFGPSLLAGAYGVLLVAGAAAA
>NC_020990.1|WP_008415881.1|4142037_4144977_+|membrane-protein
MARRTPQSSTRSTRQPQPQPLPRTRRTFGDFAKAVLAFLALAVLVVGVPLALASVIGWPLPDEAPSLDMLQREITVDTFLNVLAVVVWFAWAQFTACVLVEVKAALSGVGLPSRVPGAGPSQALARQLVAAVLLLGATAASFSPGLGQLGQQLEGHQQPAAAAAQQTPGLFGQDRAAAQSAASAVAEQAGAQAEQAAAKPSAAKGDTKYYRIQPPEGRHHDSLWEISERHLGDGRRYHEIYQLNKDRVQPDGSRLSEASLIRPGWIMEMPADATGGELVEMPDEAPKVSEELREQIADYAKSGDTATGGGSAAQEQKPDTGATDRDTQQISIPTERPAEQPQVAAPAAEGFSFGLPEALITAPLLAAGLLGALGRRRRAALWQSAMSAVGGRRGMEPPVPAGSAADVQDALLIGADPEGVRLLDRSLRGLAASLADESRPLPTVYAAWLSDGDLHLQLAQPAGEPPAPWQTGQDETFWMLARADGERYGDSEAAAPFPGLVSLGTLDDSRLLLNLEAVPGIVSLSGAAADRDAVFASVAAELATSGWSDRMTVTLVGFGEELTAIAPTRLRHLDGVPALLETMEAETRQRRGALGTAGHDSVLTGRTGPAQHTRWAPHLVLLAAEPTAEEATRLAELAADAPRLGFGYFIGTESGELPGAAWEMEITPEGRLLAPLLGLELDAQRVEAAEQRALVDLFTTADPDHEPEPGAAPPPFLVDVTEQGRPAVYARMVGPYEIIGIDAPDGSRSLLLHEALAQLLLHREGVHVRVLASALWPRGVTEDVRDALVDRLRDWLGTDEDGTPRLTTDEAGRLHLAKSVVSDLDVLRSLYHEATQGRGATDRAVRGRALTDALGLVRGPLLADRPEGRYGWLSHEIVDAQLPLLVADIGLALSAFHLEKERAGKAIEALERALSTAPDDERLWNELLRATHASGDTEALARRAADLVTRSGARGLPPRTEALLDELLPAWRDTASAAG
>NC_020990.1|WP_030773820.1|4140397_4141531_-|hypothetical-protein
MSAPAAIAAEPAPVALAGQVDQSTDLDNALFRAWVTPPAETLDDGEEIKSLSLDTGKPLKTHGSAFTLSVDPAAVPEAYIGPNGLVSLELEIYDPASQQYSWTTQSVRLVDTTTGSAAWAEPQNGQQPARGGTVKAAAVQPPTTTLKLRKASEGVAASFKTRAPVCTTTKTGQSDVWATIGSGYPAAPGYGTTRGKAWMTHSNGAEITYGAGLSTNGTNWEASGSVDVSNTKGFSFEWAASDWMTQVYRTQIRYYKYKYACDGLLRYYTMKAAAETGVVKTVKSKDLPPTWLSSSKCGFNYPAGTWTKTTGSAYSLASGVKISDIIGIDLRTSRKYTSGSTLSYKMSASHDSLCGNTDKPALAGKVQQFYNRIEEEL
>NC_020990.1|WP_030773817.1|4139693_4140308_-|hypothetical-protein
MAALLVLAVVSWLLFLRPERFEHAEGAGPLSSQTSSGSTSMYAPGKKPWTGTFGSYLLCSTTGEAITVEGIRIRTPVEPINVEQKLRKVSQKARSADPALTYLGGSLGAAPDLPDGRLPGSYQPFEPGVRIEQNCSDLDHSSAGFTELLFVLRVGDAGGLIDRVWVDYQVGGEEYTLRIEWQMIACGESIPQVDGREVCDGTAE
>NC_020990.1|WP_003948748.1|4139148_4139610_+|membrane-protein
MTLPARLRAAADRRRLDDRGSGAGAVIIFALVFLTLAAFVIDGGLSISKRERAADIAEQAARYAAQDIDREALYEDEGGPAPINYANCGARVRQFAAEMGMNGADIAASGCVAATVDQVEVEIQLTYDPVFTGMFYGGAVTVKGRSTAENAVG
>NC_020990.1|WP_008415873.1|4138672_4139152_+|TadE-like-protein
MTPTAPAARLAALVRDRRARLGLARPSAASADAGISTIEVVILAPVMILFILVLVAFGQLVDGRGALDGAARDAARAGSIQKDHGTALAEARRAAEANLADVCTGPVSVRQTSAGFEPDTLFTVEVSCQIRGLAMIGVNVPTTLTASFSSPLDPFRRTA
>NC_020990.1|WP_003948740.1|4149911_4150418_-|GNAT-family-N-acetyltransferase
MTNPPPAIGLRVPTEEDAYAWHRAFDDPEVMEFLGGKSAERSVYEEMTARQRRHDAEHGFCFWTLTDARGEVLGFTGAQPWPHDWSPAVGQIEIGWRLTRSAWGRGYVTAAARETLERVRAAGVEEVVALVDAANHRSSAVARRLGMGGPEEFRTPSGRAALCYRLKL
>NC_020990.1|WP_003948739.1|4150520_4151807_+|geranylgeranyl-reductase-family-protein
MNEPRTEQTADVIVVGAGPAGSTTAYHLAKAGLDVLLLEKTAFPREKVCGDGLTPRATKQLVAMGIDISEEAGWLRNKGLRIIGGGHRLQLDWPDLASFPDYGLVRKRDDFDEQLARQAQKAGARLHERCNVGAPITDPRTGRITGVEAKLGEEKTPVTFHAPLVVAADGNSTRLSLAMGLHRREDRPMGVAVRTYFTSPRHDDDYLESWLELWDKRGPGPDRLLPGYGWVFGMGDGTSNVGLGVLNTSASFKELDWREVLKAWCASMPEEWGYTEENMTGPIRGAALPMAFNRQPHYTKGLLLVGDAGGLVNPFNGEGIAYAMESGQIAADVIVQAHARSTPAQRERALLGYPKVLKETYGGYYSLGRAFVKLIGNPKVMKLATERGLTHPVLMRFTLKMLANLTDPTGGDAMDRVINGLTKVAPKA
>NC_020990.1|WP_018468570.1|4151904_4152693_-|C40-family-peptidase
MALRAGVAGGVLSTIAVAGSANAATAAEPVTETIEMPTLTATLTSKAALSAEATQQAADAYQYRAEQQSAAEKAVKDAKKAHKAAEKKAEAAAKKKAEERAAAAERAARSAERTDLSGVQTAAATSSSSGSSASAPSQDVPAPASGSVASVISFLQAQVGDAYVMGGTGPNSWDCSGLVQAAFKQVGVDLPRTSQEQSTAGTQVGTSNLQVGDILYWGGQGSAYHTGVYIGDGKYLDAANPSKGVVIQDLSGYPADGAVRVL
>NC_020990.1|WP_003948737.1|4153563_4153923_+|NADH-quinone-oxidoreductase-subunit-A
MNAYAPILVLGALGAAFAVFSVVMATLIGPKRYNRAKLEAYECGIEPTPTPAGGGRFPIKYYLTAMLFIVFDIEIVFLYPWAVSFDALGLFGLVEMLLFVLTVFVAYAYVWRRGGLEWD
>NC_020990.1|WP_003948736.1|4153974_4154529_+|NADH-quinone-oxidoreductase-subunit-B
MGLEEKLPSGFLLTTVEQAAGWVRKSSMFPATFGLACCAIEMMTTGAGRYDLARFGMEVFRGSPRQADLMIVAGRVSQKMAPVLRQVYDQMPNPKWVISMGVCASSGGMFNNYAIVQGVDHIVPVDIYLPGCPPRPEMLVDAIVKLHQKVQSSKLGVNKEEAAREAEEAALKALPTIEMKGLLR
>NC_020990.1|WP_003948735.1|4154525_4155281_+|NADH-quinone-oxidoreductase-subunit-C
MSDTHQDPEEPREESALPAARREGGDVIGVRRGMFGAQDTGDTSGYGGLVRTVSLPGPASRPYGGPTSREGYGVFDEIADELEGALDEQGLLPANAIDRTVVDRGELTFHIEREHLLRVARTLRDDPALRFELCTGVSAVHYPEDKGRELHAVYHLRSITHKRLIRLEVSAPDADPHIPSLVSVYPTNDWHEREAYDFFGLIFDGHPALTRLMMPDDWQGHPQRKDYPLGGIAVEYKGAQIPAPDQRRSYS
>NC_020990.1|WP_015507701.1|4155280_4156660_+|NADH-quinone-oxidoreductase-subunit-D
MSTSHPRQEAGHATAAEEDAVGYSAGRETTEGTVYTVTGGDWDEIAEAAAKSDDERIIVNMGPQHPSTHGVLRLILEIDGETVTEARCGIGYLHTGIEKNLEYRTWTQGTTFVTRMDYLTPFYNEAAYCLGVEKLLGIEDQVPDRASVIRVLLMELNRLSSHLVAIATGGMELGATTIMIYGFRDREVVLDLFELITGLRMNHAFIRPGGLAQDLPAGALDQVREGVKTLRKNIDEYDKLATGNPLFQGRMKGIGYLDLAGCMSLGITGPVLRSTGLPHDLRKTDPYCGYETYDFEVPTADTCDSYGRFLIRLAEMRESLKIVEQCLDRLREPGEVMVSDKKIAWPAQLALGPDGLGNSLDHIKKIMGTSMESLIHHFKLVTEGFRVPPGQAYAAVESPKGELGAHIVSDGTTRPYRVHFRDPSFTNLQAVAAMCEGGQVADVIVAVASIDPVMGGVDR
>NC_020990.1|WP_030772685.1|4156695_4157532_+|NADH-quinone-oxidoreductase-subunit-NuoE
MPQLPAPAYPAETHARLKADAEAIIARYPDSRSALLPMLHLVQSEEGYVTRTGMAFCAELLGLTTAEVTAVATFYTMYRRKPSGDYQVGVCTNTLCAVMGGDAIFDELKEHLGVGNDETTEDGKITLEHIECNAACDYAPVVMVNWEFFDNQTPDSAKRLVDDLREGRTVEPTRGAPLCTYKETARILAGFPDERPGAVEATGGAGPASLIGLKLAKGELPQQRVVHPRGQDGAPDATGHAPSPAEHLSSHDAPQQTAPSDPENPAGPVTGDGSEEGK
>NC_020990.1|WP_003948732.1|4157531_4158881_+|NADH-quinone-oxidoreductase-subunit-NuoF
MTVATEMNQTSPDKLLAPVLSAFWDQPESWTLETYRRHDGYEGLRKALAMSPDDLIAYVKDAGLRGRGGAGFPTGMKWQFIPQGDGKPHYLVVNADESEPGTCKDIPLLFANPHSLIEGIVIACYAIRSSHAFIYLRGEVVPVLRRLHEAVREAYEAGYLGKDVLGSGLDLDLTVHAGAGAYICGEETALLDSLEGRRGQPRLRPPFPAVAGLYACPTVVNNVESIASVPAILQQGKEWFRSMGSEKSPGFTLYSLSGHVAGPGQYEAPLGITLRQLLDMSGGMRPGHRLKFWTPGGSSTPMFTDEHLDVPLDYEGVGAAGSMLGTKALQCFDETTCVVRAVTRWTEFYAHESCGKCTPCREGTYWLVQLLRDIEAGQGKMSDLDKLNDIADNINGKSFCALGDGAASPIFSSLKYFRDEYEQHITGKGCPFDPAKSTLWADQHLEAKA
>NC_020990.1|WP_003948731.1|4158877_4161406_+|NADH-quinone-oxidoreductase-subunit-G
MTVTTGAAPGTPAGVPPEDLVTLTIDGIEISVPKGTLVIRAAELLGIEIPRFCDHPLLDPAGACRQCIVEVEGQRKPMASCTITCTEGMEVRTQLTSPVAEKAQRGVMELLLINHPLDCPVCDKGGECPLQNQAMQVGDPDSRFEGKKRTYEKPVPISTQVLLDRERCVLCARCTRFSNQVAGDPMIELIERGALQQVGTGDGDPFESYFSGNTIQICPVGALTSAAYRFRSRPFDLVSSPSVCEHCAGGCATRTDHRRGKVMRRLAADDPEVNEEWMCDKGRFGFRYAQSPERLTQPLVRSESGVLEPASWPEALQAAARGLNAARGRAGVLTGGRLTVEDAYAYSKFARVALDTNDIDFRARPHSGEEADFLASQVAGRGRDLDGGGLTYADLEQAPAVLLAGIEAEEEAPGVFLRLRKAWRKKGQRTFALATHTTRGLTKAGGTLLPAAPGTETEWLKALGTGFGLEGVGQEAGEALRAEGSVIVVGERLATVEGGLTAAVRAAAALGARLVWIPRRAGERGAVEAGALPSLLPGGRPATDPRAREEVAAAWGVAELPPRYGRDTGQIVEAAASGELTALLVGGVEVADLPDPARARQALDRAEFVVSLEQRPSEVTERADVVLPVAAVAEKSGTFLNWEGRSRMFEAALKPEQMTRRLAPGDLRVLHMLADAVAEADETGRGELALPDIRAARRELDRLGGWDARPSRPAVPPEAPAGSALPRPAAGEAVLAGHRMLLDQGLLQRGDEALAGTRHAAPARLSAATAAEIGAADGTVLTVAGPAGSVELPLLVTDMPDRVVWLPLNSTGTGVASDTGAVPGQLVRIAPAAEAPAEVEES

Crispr_ID: NC_020990_23

• CRISPR_ID: NC_020990_23
• CRISPR_location: 4406080-4406165
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_23

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NC_020990_23

>23.1|4406103|40|NC_020990|CRISPRCasFinder
GTCGTTTGGCTGGGGTGGTGCCTCAGCCACCGGTCCAAGA

CRISPR arrays and Neighbor proteins around NC_020990_23

CRISPR arrays

The CRISPR arrays of NC_020990_23

>merge|NC_020990|23|4406080-4406165|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGTCGTTTGGCTGGGGTGGTGCCTCAGCCACCGGTCCAAGATGGCCTCAATCGCCGGCCGGGCT

>NC_020990|23|18|4406080-4406165|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCT	GTCGTTTGGCTGGGGTGGTGCCTCAGCCACCGGTCCAAGA
TGGCCTCAATCGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003948497.1|4405522_4406056_+|DUF3017-domain-containing-protein	unknown	unknown	gnl|CDD|378602
NC_020990.1|WP_003948506.1|4394883_4396062_+|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234813
NC_020990.1|WP_008410620.1|4403683_4404331_-|hypothetical-protein	unknown	unknown	gnl|CDD|370723
NC_020990.1|WP_003948493.1|4410211_4411201_+|malate-dehydrogenase	unknown	unknown	gnl|CDD|235468
NC_020990.1|WP_003948498.1|4404636_4405500_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase	unknown	unknown	gnl|CDD|237637
NC_020990.1|WP_003948487.1|4416518_4417640_+|glycine-betaine/L-proline-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213261
NC_020990.1|WP_008412695.1|4397072_4398290_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NC_020990.1|WP_015507754.1|4406624_4407437_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|366659
NC_020990.1|WP_003948488.1|4415004_4416522_+|oxidoreductase	unknown	unknown	gnl|CDD|235000
NC_020990.1|WP_015507755.1|4407433_4408300_+|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|371292
NC_020990.1|WP_008410350.1|4413311_4414814_+|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143437
NC_020990.1|WP_015507753.1|4400201_4401080_-|hypothetical-protein	unknown	unknown	gnl|CDD|366494
NC_020990.1|WP_015507757.1|4411348_4412137_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948491.1|4412209_4412473_-|hypothetical-protein	unknown	unknown	gnl|CDD|367351
NC_020990.1|WP_041826608.1|4398470_4400153_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948505.1|4396082_4396967_+|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|180194
NC_020990.1|WP_008410614.1|4401391_4402048_+|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl|CDD|235544
NC_020990.1|WP_015507756.1|4408800_4409868_+|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|371292
NC_020990.1|WP_003948500.1|4402044_4403607_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl|CDD|234854
NC_020990.1|WP_003948490.1|4412559_4412880_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003948497.1|4405522_4406056_+|DUF3017-domain-containing-protein	gnl|CDD|378602	pfam11222, DUF3017, Protein of unknown function (DUF3017). This bacterial family of proteins with unknown function appear to be restricted to Actinobacteria.	2.9369e-19
NC_020990.1|WP_003948506.1|4394883_4396062_+|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl|CDD|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NC_020990.1|WP_008410620.1|4403683_4404331_-|hypothetical-protein	gnl|CDD|370723	pfam09849, DUF2076, Uncharacterized protein conserved in bacteria (DUF2076). This domain, found in various hypothetical prokaryotic proteins, has no known function. The domain, however, is found in various periplasmic ligand-binding sensor proteins.	0.000337301
NC_020990.1|WP_003948493.1|4410211_4411201_+|malate-dehydrogenase	gnl|CDD|235468	PRK05442, PRK05442, malate dehydrogenase; Provisional.	0
NC_020990.1|WP_003948498.1|4404636_4405500_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase	gnl|CDD|237637	PRK14193, PRK14193, bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional.	0
NC_020990.1|WP_003948487.1|4416518_4417640_+|glycine-betaine/L-proline-ABC-transporter-ATP-binding-protein	gnl|CDD|213261	cd03294, ABC_Pro_Gly_Betaine, ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system. This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	2.54089e-163
NC_020990.1|WP_008412695.1|4397072_4398290_-|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	7.91727e-09
NC_020990.1|WP_015507754.1|4406624_4407437_+|helix-turn-helix-domain-containing-protein	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	2.67897e-15
NC_020990.1|WP_015507755.1|4407433_4408300_+|XRE-family-transcriptional-regulator	gnl|CDD|371292	pfam10901, DUF2690, Protein of unknown function (DUF2690). This bacterial family of proteins has no known function.	2.77751e-06
NC_020990.1|WP_015507753.1|4400201_4401080_-|hypothetical-protein	gnl|CDD|366494	pfam01153, Glypican, Glypican.	0.00160618
NC_020990.1|WP_008410350.1|4413311_4414814_+|aldehyde-dehydrogenase-family-protein	gnl|CDD|143437	cd07119, ALDH_BADH-GbsA, Bacillus subtilis NAD+-dependent betaine aldehyde dehydrogenase-like. Included in this CD is the NAD+-dependent, betaine aldehyde dehydrogenase (BADH, GbsA, EC=1.2.1.8) of Bacillus subtilis involved in the synthesis of the osmoprotectant glycine betaine from choline or glycine betaine aldehyde.	0
NC_020990.1|WP_003948491.1|4412209_4412473_-|hypothetical-protein	gnl|CDD|367351	pfam03137, OATP, Organic Anion Transporter Polypeptide (OATP) family. This family consists of several eukaryotic Organic-Anion-Transporting Polypeptides (OATPs). Several have been identified mostly in human and rat. Different OATPs vary in tissue distribution and substrate specificity. Since the numbering of different OATPs in particular species was based originally on the order of discovery, similarly numbered OATPs in humans and rats did not necessarily correspond in function, tissue distribution and substrate specificity (in spite of the name, some OATPs also transport organic cations and neutral molecules). Thus, Tamai et al. initiated the current scheme of using digits for rat OATPs and letters for human ones. Prostaglandin transporter (PGT) proteins are also considered to be OATP family members. In addition, the methotrexate transporter OATK is closely related to OATPs. This family also includes several predicted proteins from Caenorhabditis elegans and Drosophila melanogaster. This similarity was not previously noted. Note: Members of this family are described (in the Swiss-Prot database) as belonging to the SLC21 family of transporters.	0.00133628
NC_020990.1|WP_015507756.1|4408800_4409868_+|XRE-family-transcriptional-regulator	gnl|CDD|371292	pfam10901, DUF2690, Protein of unknown function (DUF2690). This bacterial family of proteins has no known function.	3.18799e-16
NC_020990.1|WP_003948505.1|4396082_4396967_+|succinate--CoA-ligase-subunit-alpha	gnl|CDD|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NC_020990.1|WP_008410614.1|4401391_4402048_+|phosphoribosylglycinamide-formyltransferase	gnl|CDD|235544	PRK05647, purN, phosphoribosylglycinamide formyltransferase; Reviewed.	2.31986e-109
NC_020990.1|WP_003948500.1|4402044_4403607_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl|CDD|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NC_020990.1|WP_003948488.1|4415004_4416522_+|oxidoreductase	gnl|CDD|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	1.80522e-119

Protein sequences

>NC_020990.1|WP_003948497.1|4405522_4406056_+|DUF3017-domain-containing-protein
MSTDAPDDRPTAEQTPEAPEPRPEPAGGASRAGAGVRTGVAKLGWTRREPGSRRFPRITRSIARPEGGGRAAAGDAPAPARQWPMLLVLSLVGLGLILTAFDVTRVGTLLIGVALLVGAGLRWWLPSVGMLAVRSRFTDLVTYSVLGVVIVVLALMQQPDPLLELPFLDRTLHFTVD
>NC_020990.1|WP_003948498.1|4404636_4405500_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase
MSAQILDGKATAAAIKSELAQRVAALRAQGVLPGLGTVLVGEDPGSQKYVAGKHRDCAQVGIASIQRELPATATQEEIEAVVRELNEDPACTGYIVQLPLPKGIDENRILELMDPAKDADGLHPTNLGRLVLNEPAPLPCTPFGIVTLLRHFGVEINGAEVVVVGRGVTIGRPMPLLLTRRSENATVTQCHTGTRDLAAHLRRADIIVAAAGVPHLVKPEDVKPGAAVLDVGVSRDENGKIVGDVHPGVAEVAGWISPNPGGVGPMTRAQLLVNVVEAAERQAASAA
>NC_020990.1|WP_008410620.1|4403683_4404331_-|hypothetical-protein
MSFGDPNNPYGPPQGQPGGYGSPQGQPGGYGAPQGQPAYGYPQQGGQPGQPGYGYPQQGGQPGYPGGPGMNPMKPEMPGLMKTARVLLFIVAGLQILVGLLFGVAIGAAKDVANGMDTDAANGLVGLGYVLVFLLLALAVLAIVLGVKFSTGGSGIRITTIVYASLMLLGSLSNLFAGEGGSATFGGIVALAIYGIILAAMVNSQASVWFNRPRY
>NC_020990.1|WP_003948500.1|4402044_4403607_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MTAEGTKRPIRRALVSVYDKTGLEELARGLHEAGVELVSTGSTAGRIAAAGVPVTKVEELTGFPECLDGRVKTLHPRVHAGILADLRLDSHREQLAELGVEPFQLVIVNLYPFRETVASGATPDECVEQIDIGGPSMVRAAAKNHPSVAVVTDPGQYGAVLEAARDGGFELAARKRLAAKAFQHTAAYDVAVASWFADDYAAADDSGFPDFLGSALTRSTVLRYGENPHQPAALYTLGEGGLAEAEQLHGKEMSYNNYTDTDAARRAAYDHADPCVAIIKHANPCGIAVAGDVAEAHRKAHACDPLSAFGGVIAVNRPVTREMAEQVAEIFTEVIVAPDYEDGALEALTRKKNIRVLRCPEPPAATVETKQIDGGALLQEADRLQAGGDSPANWTLATGDALGEGELAELAFAWRACRAVKSNAILLAKDGASVGVGMGQVNRVDSAKLAVERAGEERARGAFAASDAFFPFPDGLEILLEAGVRAVVQPGGSVRDELVVEAAKKAGVTMYFTGTRHFFH
>NC_020990.1|WP_008410614.1|4401391_4402048_+|phosphoribosylglycinamide-formyltransferase
MASPLPSAASSRPKRLVVLVSGSGTNLQALLDAIAAQGAGAYGAEVVAVGADRGAIAGLDRAERAGIPSFVCRVKDHPDRAAWDRALTEAVAAYEPDLVVSAGFMKILGKEFLARFGGRVVNTHPALLPSFPGAHGVRDALAYGVKVTGCTVHLVDDGVDTGPIIAQGVVEVVEDDSAEGEAALHERIKDVERTLLVEVVGRLARNGHRIEGRKVLIP
>NC_020990.1|WP_015507753.1|4400201_4401080_-|hypothetical-protein
MPDRRSAVSLRLPLPTAAPGFGGLALPGAAATAPDAWGVVAVRESSEKERKSSSEPEGRSGSDSGSGSDSGSGQSDNPFAAPPEGRPDQPWKPRTPAGGSDDGSGQGGGGGRWSDRQPGRSPNPFGSGSRDGSGEGRPPGPRWDPRDPGQRRARYALLSGMWSFFFALFNWPSVALLLGALSVYWGVTSLKMRGKPAEGADGEAREKRGPGESAPAPTESGTRQQTTAAVSGLVTAGLGLALVAAMFGARIVYSDYYSCMDDALTNATRDTCEKHLPKDLRPLLGVNTENNG
>NC_020990.1|WP_041826608.1|4398470_4400153_+|hypothetical-protein
MTDDSLSPAARLQALADRLRDRSPALAGCLFGGAVAAGLGLGAYAVVVMALWIGSPYPDSGPGGATGTAVSLWLLGHGVGLTRADTLTGVPAPLGLTPLLLALLPFWLVRRAARDAAEPETPQAPEIPARTVVWGVTGGYTAVGALAALYATGGELRPTLREAAWHLPLLALAAALTGLRSVRGRGADAPSPAGPDGGSGGVRAALAGRRGATACRAGLAAALTLAGGGAVLVGVSLTLHRDPARASYLMLTDVWSGRLAVLLLALALLPNAVIWGAAYALGTGFQVGTGTLVTPLAATSGPALPPFPLLAAVPPDGSGTPLTWACAAIPVVAGITAGWFTGRAAAPDRSSGTDAEGAPPPWSAPVTAATAALAALVAGLVCAVAARAAGGPLGTGRLAELGPVWWAAGGAALAWTLLLGVPTALALRAWRLRTRKPREAGSGGGRWAGAGLFGIAMTGTGLAVPGAADGGTDPEARPGADADIEEEAAESDDDPERVDPLDWWERVSRPDPVAALGGSFGTPYDLYDQLPAHGPEDWRALPAEEQAPPGERPAGREPDA
>NC_020990.1|WP_008412695.1|4397072_4398290_-|helix-turn-helix-domain-containing-protein
MTNRPAPTLPTPAERRRLREAASLSQAALAARMSVTSTTIHSWETGRATPRGRALEAYASFLTTTADRPGPAGKPVRTSRSQAGTAVKGGEDKARGEVGEKAEAPPEPARAEASRPRPARPEPPRPSPRPPRPTGATPREAFDALYASCAGVLVRQTYLLTGRHTVAVESVERAFQLAWARWPEVAVDRDPAGWVRAAAHEYALSPWHRMRAAHRRPATPGAVLPPPRGRADHDLMDALLSLAPRHRRTLLLYDGVGLDLPETAAETEATTRAAAHRVLSARAAVAERVPALADPAALHRRLDALSPLEPATEEQGALIRTGGERRVRRWTRSAVVLTAVIAGATAFCVSVAPDHYVRPPAAGEAITGVPPHAGPGPLSEEDRSLREKLREHPAAGPERVRPLPR
>NC_020990.1|WP_003948505.1|4396082_4396967_+|succinate--CoA-ligase-subunit-alpha
MAIFLTKDSKVIVQGMTGATGMKHTKLMLGDGTNIVGGVNPRKAGTSVDFDGTEVPVFGSVAEAIEKTGADVSVIFVPPKFAKAAVVEAIDAEIGLAVVITEGIAVHDSAAFWAYASSKGNKTRIIGPNCPGLITPGQSNAGIIPGDITKPGRIGLVSKSGTLTYQMMYELRDIGFSSAVGIGGDPVIGTTHIDALAAFEADPETDLIVMIGEIGGDAEERAADYIKANVTKPVVGYVAGFTAPEGKTMGHAGAIVSGSSGTAQAKKEALEAAGVKVGKTPTETAELARAILAG
>NC_020990.1|WP_003948506.1|4394883_4396062_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MDLFEYQARDLFAKHGVPVLAGEVIDTPEAAREATERLGGKSVVKAQVKVGGRGKAGGVKLAATPDEAVARATDILGMDIKGHTVHKVMIAETAPEIVEEYYVSYLLDRTNRTFLAMASVQGGMDIEEVAEKTPEALAKVPVDSNTGVTIEKAREIVAQAKFPAEVAEKVAEVMVTLWDTFVAEDALLVEVNPLAKVASGEVLALDGKVSLDENADFRQPDHEALEDKAAANPLEAAAKAKNLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGEKHGNVKPANFLDIGGGASAEVMANGLEIILGDPDVKSVFVNVFGGITACDEVANGIVQALELLKTKGEDVTKPLVVRLDGNNAELGRKILSDANHPLVQRVDTMDGAADKAAELAAAK
>NC_020990.1|WP_015507754.1|4406624_4407437_+|helix-turn-helix-domain-containing-protein
MARWAELPAGLDRRERQLVVQLRRLKDHSGLSLSALGARTGYSRSSWERYLSGRAPVPRAAVIGLAEVCGVDPTRLLALHEVATEHRAADGHSTGTAQPLADTGPASRSWAGEHPEPPGPPAGRRRTAVAAALLVGAVALGFAVGLTTGLVAGSGTRAAAGPGRADGPDLVRPDGERWRRGAEHTCRVHRAEGLLHAGHSHERTAYLDINSSGWHVVEAQCLLRHHGVDPGAVDGLYGPVVQEAVRRFQAARRIPVDGVVGPDTWGELRR
>NC_020990.1|WP_015507755.1|4407433_4408300_+|XRE-family-transcriptional-regulator
MTDDATPPECRRLLGELRSLRERSGHSLAALAAVTPYSKSSWGRYLSGAQPVPRAAVVALCQVAGERPARLLALWELADAEWSGRGSYTVQVRTGTPGAPAAPAETGITAEPVARPSRRRRSRWLLVAGAVLAVVAGAGAGVKALAERAPLAAASEPDAGPWRQDGPLVHGCTGPGCDGLAPGALGCDRADAVVTLAEHRTGEGRRVQVRYGRDCRALWARASGLRAGDRFALRLPGAPARTAGPVGGEEAAGYLATLMTGVSGPGAAAGATACLLPVHGPEECAPVR
>NC_020990.1|WP_015507756.1|4408800_4409868_+|XRE-family-transcriptional-regulator
MARWKPLPEELDPQVREFAGQLRRLVDRSGLSIAAVSDRTGYSKTSWERYLNGRLLAPKRAIIALAEATGTNPVHLTTMWELAERAWSRSEMRHDMTMEAIRITQARAALGDFTPPQGIDLGHRAPKAGARAKVNGADGPGGRGGAPAGVREAPPIPSVPRQPGPPGAAVPPGPLPGGDASGGSGKGGKGKGRRLPLILGGAVAALALVAGGFFLLAPGDEPAPQPTAKPTKTAKKLPAGVKCAGADCTGEDPEAMGCAGEQAVTSATATVGPTVVEIRYSKTCEAAWARITQAATGDEIAIDVGTEAQESAKVATTFDAYTAMLAVENPADAKACATLAAGTTGCTTPSTTPTP
>NC_020990.1|WP_003948493.1|4410211_4411201_+|malate-dehydrogenase
MTRTPVNVTVTGAAGQIGYALLFRIASGHLLGADVPVRLRLLEIPQGLKAAEGTAMELDDCAFPLLQGIEITDDPNVGFDGANVALLVGARPRTKGMERGDLLEANGGIFKPQGKAINDHAADDIKVLVVGNPANTNALIAQAAAPDVPAERFTAMTRLDHNRALSQLAKKTGAQVSDIKKLTIWGNHSATQYPDIFHAEIAGKNAAEVIADEQWLADDFIPTVAKRGAAIIEARGASSAASAANAAIDHVHTWVNGTAEGNWTSMGIPSDGSYGVPEGLISSFPVTTKNGTYEIVQGLDINEFSRARIDASVQELAEERDAVRALGLI
>NC_020990.1|WP_015507757.1|4411348_4412137_-|hypothetical-protein
MPHPIRAAAAAAASTLLAATAALAAPGAAPAAEDDLSRLSAEEIAERARTELRGAASLRVTLDQDQFDGGTGALEDPATADLAMDERGRCAGNVTLTRGRGSVELVKRGDEVWVKPDRDFWEAQLPGGQGTAAADTLHGRYVHGSPRDGVLAAVTEACDLDSLKEDLTGEATPDKGTRMTKGAATTAVFTPVIPLLRQGDGERVTLYVATEGPPRLVQATRTSDVKEDTVTVTGYGATVRAEPPAEEDTVDLSTLRDRLGPL
>NC_020990.1|WP_003948491.1|4412209_4412473_-|hypothetical-protein
MLRNWWDLERTEELSPRQERWLRRAWWLYWSMLALSVGLVVLRVVEGDPPLQILFSALLVAVWIFNLYALRKRLRGHEAASAARQEG
>NC_020990.1|WP_003948490.1|4412559_4412880_+|hypothetical-protein
MWGTPKNQTRLRFVQDSDEVLAALERTLADAPESERPGLRRALAVARAARLDEDTLRTRWLDARLASVAFTGDRDSVAAVRALRKAEPTLSLTEAVSLLRPPKPDA
>NC_020990.1|WP_008410350.1|4413311_4414814_+|aldehyde-dehydrogenase-family-protein
MSAEQTIYVDGTWRAATSGAVREIIDPADAKPFAVVAEGGTEDADAAVAAARRAFDQGPWPRTPVAERAALLRRVADLLVRDREEIGLLESRDAGKTLEEGRVDVDCVADAFRYFADLVVGEGAGRVVDAGTDEVHSVVVHEPVGVCGLITPWNYPLLQASWKVAPALAAGNTFVLKPSEITPLSTIALMRLLAEAGLPEGVANLVTGPGHTVGARFGTHDDVDLVSFTGGLVSGTKVAQAAAASVKKVALELGGKNPNVVFADACATDEDFDTAVDQALNAAFIHSGQVCSAGSRLIVEESVRERFVTELTRRAQLIRLGRGTEEGVECGPLVSQAQLEKTQGFVASALEEGAVLRTGGKQPEPSEVRPATGYFYEPTVLDGCHREMRVVREEVFGPVLTVETFTTEDEAVALANDTEYGLAGAVWTTDAGRARRVAARLRHGTVWINDFHPYLPQAEWGGFGKSGTGRELGPAGLAEYRESKHVYQNLAPKPVRWFAG
>NC_020990.1|WP_003948488.1|4415004_4416522_+|oxidoreductase
MPTYDYVVIGGGTAGSVIASRLTENPDTTVAIIEGGPSDIDRPDVLTLRRWMGLLGGDLDYDYPTTEQPRGNSHIRHSRAKVLGGCSSHNTLIAFKPLPSDWDEWETAGAEGWGAVPMEAYYARLKNNIVPVDEKDRNAIARDFVDAAQGALGVPHVDGFNQKPFSEGVGFFDLAYHPENNKRSSASVAYLHPYLDRPNLHLMLETWAYQLAFDGDRATGVHVRTKDGEEILVEAGREVLLCAGAVDSPRLLLHSGIGPRADLEKLGITVRHDLPGVGENLLDHPESVIVWETDGPIPENSAMDSDAGLFVRRDPKGRGPDLMFHFYQIPFTDNPERLGYERPAHGVSMTPNIPKPHSRGRLYLTSADPEVKPALDFRYFTDEDDYDAQTLVDGIKIARRIARTEPLAGWLKREVAPGPGITDDEALSEYARKVAHTVYHPAGTCRMGAEDDELAVVTPELKIRGLTNIRIADASVFPTMPAVNPMIGVLMVGEKCAEMLGGDAR
>NC_020990.1|WP_003948487.1|4416518_4417640_+|glycine-betaine/L-proline-ABC-transporter-ATP-binding-protein
MSATTTATPPGREAPADENTPVFSVENLWKVFGPKAERVPADPALAALDPVELRAATGCTAAVHDVSFDVRQGEVFVVMGLSGSGKSTLVRCLTRLIEPTAGKLAMYGEDVRAMDKNRLRELRRRRAAMVFQHFGLLPHRTVLDNVAYGLEIQGVPRAERRAKAAETAALVGLEGLEDRRPGQLSGGQQQRVGLARALAVDPEVLLFDEPFSALDPLIRRDMQEEVKRLHQEEGRTMVFITHDLSEALRLGDRIALMRDGRVVQLGTPEEIVGSPADDYVRDFVRDVPREQVLTVRTAMRPATGSEAEQGPALSPGATVSEAIEAVARTGETARVVDSGRCLGVVDHHRLLGVVAGADPGPAAPPAKAGEAVL

Crispr_ID: NC_020990_24

• CRISPR_ID: NC_020990_24
• CRISPR_location: 4431989-4432202
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_020990_24

Consensus_repeat	Method
GGGACCACCCCCGCGTGCGCGGGGACCACTC	CRISPRCasFinder

spacers of NC_020990_24

>24.1|4432020|30|NC_020990|CRISPRCasFinder
GATGATGTTCGTGACGACCGGAGTGGCCTC
>24.2|4432081|30|NC_020990|CRISPRCasFinder
GACGCGCCACAGCTCGTCGAGGACGAGGTA
>24.3|4432142|30|NC_020990|CRISPRCasFinder
GCCGACCAGCCACACCCGCCGGTGCGGGAG

CRISPR arrays and Neighbor proteins around NC_020990_24

CRISPR arrays

The CRISPR arrays of NC_020990_24

>merge|NC_020990|24|4431989-4432202|CRISPRCasFinder
GAGGCTTGCCCCGCCTGCGCGGGGACCACTCGATGATGTTCGTGACGACCGGAGTGGCCTCGGGACTACCCCCGCGTGTGCGGGGACCACAGGACGCGCCACAGCTCGTCGAGGACGAGGTAGGGACCACCCCCGCGTGCGCGGGGACCACTCGCCGACCAGCCACACCCGCCGGTGCGGGAGGGGACCACCCCCGCGTGCGCGGGGACCACTC

>NC_020990|24|19|4431989-4432202|CRISPRCasFinder
GAGGCTTGCCCCGCCTGCGCGGGGACCACTC	GATGATGTTCGTGACGACCGGAGTGGCCTC
GGGACTACCCCCGCGTGTGCGGGGACCACAG	GACGCGCCACAGCTCGTCGAGGACGAGGTA
GGGACCACCCCCGCGTGCGCGGGGACCACTC	GCCGACCAGCCACACCCGCCGGTGCGGGAG
GGGACCACCCCCGCGTGCGCGGGGACCACTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003948474.1|4432462_4432675_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948464.1|4441180_4442017_-|DUF1206-domain-containing-protein	unknown	unknown	gnl|CDD|377695
NC_020990.1|WP_015507761.1|4428899_4429754_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_020990.1|WP_003948471.1|4435182_4435761_+|hypothetical-protein	unknown	unknown	gnl|CDD|240430
NC_020990.1|WP_015507763.1|4437168_4437702_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NC_020990.1|WP_003948481.1|4424213_4425047_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_020990.1|WP_003948473.1|4432806_4433364_-|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|225039
NC_020990.1|WP_015507759.1|4422952_4424146_-|family-1-glycosylhydrolase	unknown	unknown	gnl|CDD|274539
NC_020990.1|WP_003948484.1|4420810_4421275_+|VOC-family-protein	unknown	unknown	gnl|CDD|319898
NC_020990.1|WP_003948480.1|4425043_4425994_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_020990.1|WP_003948470.1|4435904_4437125_+|glutathionylspermidine-synthase-family-protein	unknown	unknown	gnl|CDD|367631
NC_020990.1|WP_003948472.1|4433470_4434898_+|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NC_020990.1|WP_003948476.1|4429802_4430681_-|M55-family-metallopeptidase	unknown	unknown	gnl|CDD|176450
NC_020990.1|WP_008410798.1|4440259_4441087_+|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|379142
NC_020990.1|WP_003948468.1|4437715_4438969_-|ornithine--oxo-acid-transaminase	unknown	unknown	gnl|CDD|179736
NC_020990.1|WP_037629598.1|4427865_4428765_+|acetylxylan-esterase	unknown	unknown	gnl|CDD|225989
NC_020990.1|WP_003948475.1|4430718_4431828_-|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NC_020990.1|WP_010638599.1|4425999_4427250_-|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270450
NC_020990.1|WP_003948467.1|4439325_4439823_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948483.1|4421335_4422856_-|VCBS-repeat-containing-protein	unknown	unknown	gnl|CDD|379232

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_015507763.1|4437168_4437702_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.47847e-12
NC_020990.1|WP_003948464.1|4441180_4442017_-|DUF1206-domain-containing-protein	gnl|CDD|377695	pfam06724, DUF1206, Domain of Unknown Function (DUF1206). This region consists of two a pair of transmembrane helices and occurs three times in each of the family member proteins.	6.2428e-13
NC_020990.1|WP_015507761.1|4428899_4429754_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.06088e-15
NC_020990.1|WP_003948471.1|4435182_4435761_+|hypothetical-protein	gnl|CDD|240430	PTZ00473, PTZ00473, Plasmodium Vir superfamily; Provisional.	0.00532253
NC_020990.1|WP_003948481.1|4424213_4425047_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	2.0156e-89
NC_020990.1|WP_003948473.1|4432806_4433364_-|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	2.18171e-27
NC_020990.1|WP_015507759.1|4422952_4424146_-|family-1-glycosylhydrolase	gnl|CDD|274539	TIGR03356, BGL, beta-galactosidase.	1.58452e-83
NC_020990.1|WP_003948484.1|4420810_4421275_+|VOC-family-protein	gnl|CDD|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	1.29354e-14
NC_020990.1|WP_003948480.1|4425043_4425994_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.31685e-90
NC_020990.1|WP_003948470.1|4435904_4437125_+|glutathionylspermidine-synthase-family-protein	gnl|CDD|367631	pfam03738, GSP_synth, Glutathionylspermidine synthase preATP-grasp. This region contains the Glutathionylspermidine synthase enzymatic activity EC:6.3.1.8. This is the C-terminal region in bi-enzymes. Glutathionylspermidine (GSP) synthetases of Trypanosomatidae and Escherichia coli couple hydrolysis of ATP (to ADP and Pi) with formation of an amide bond between spermidine and the glycine carboxylate of glutathione (gamma-Glu-Cys-Gly). In the pathogenic trypanosomatids, this reaction is the penultimate step in the biosynthesis of the antioxidant metabolite, trypanothione (N1,N8-bis-(glutathionyl)spermidine), and is a target for drug design. This region, the pre-ATP grasp region, probably carries the substrate-binding site.	1.20264e-172
NC_020990.1|WP_003948472.1|4433470_4434898_+|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.9457e-106
NC_020990.1|WP_003948476.1|4429802_4430681_-|M55-family-metallopeptidase	gnl|CDD|176450	cd08663, DAP_dppA_1, Peptidase M55, D-aminopeptidase dipeptide-binding protein family. M55 Peptidase, D-Aminopeptidase dipeptide-binding protein (dppA; DAP dppA; EC 3.4.11.-) domain: Peptide transport systems are found in many bacterial species and generally function to accumulate intact peptides in the cell, where they are hydrolyzed. The dipeptide-binding protein (dppA) of Bacillus subtilis belongs to the dipeptide ABC transport (dpp) operon expressed early during sporulation. It is a binuclear zinc-dependent, D-specific aminopeptidase. The biologically active enzyme is a homodecamer with active sites buried in its channel. These self-compartmentalizing proteases are characterized by a SXDXEG motif. D-Ala-D-Ala and D-Ala-Gly-Gly are the preferred substrates. Bacillus subtilis dppA is thought to function as an adaptation to nutrient deficiency; hydrolysis of its substrate releases D-Ala which can be used subsequently as metabolic fuel. This family also contains a number of uncharacterized putative peptidases.	5.76205e-124
NC_020990.1|WP_008410798.1|4440259_4441087_+|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	7.11501e-07
NC_020990.1|WP_003948468.1|4437715_4438969_-|ornithine--oxo-acid-transaminase	gnl|CDD|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
NC_020990.1|WP_037629598.1|4427865_4428765_+|acetylxylan-esterase	gnl|CDD|225989	COG3458, COG3458, Acetyl esterase (deacetylase) [Secondary metabolites biosynthesis, transport, and catabolism].	5.51495e-53
NC_020990.1|WP_003948475.1|4430718_4431828_-|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	6.77364e-89
NC_020990.1|WP_010638599.1|4425999_4427250_-|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.70213e-130
NC_020990.1|WP_003948483.1|4421335_4422856_-|VCBS-repeat-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	2.66638e-05

Protein sequences

>NC_020990.1|WP_003948475.1|4430718_4431828_-|LacI-family-transcriptional-regulator
MGDGVAGTPTVYDVAGRAGVSIATVSRVYRSPESVREATREKVLVAARELGYVPSGSARGLASRSTGVLGLCFPDYSDPDAESEAATVDADDDHAFMLYSDQIIRGMERAARRHGYALLIAASLTGGPESLVAKVAGRVDGCAVLARTVPTEDLEVISRRLPVVMLAGPPEQDGPGGLDRLDHIEVANAEGQRELTRHLIEDHGLRRLTFVGGIEDSPDAEARFAGFRDACRAAGLPVPDEPDLRAELMTQAGGARAAEELVDRAGPDGLPEGVLFANDQMAVGALHALARRGLRVPEDLAVTGFDGIPLGRLVQPTLTTVRQPMRRLGEEAVELLVRRLAEEKRGEPESLVLPVEVVRRASCGCGHEA
>NC_020990.1|WP_003948476.1|4429802_4430681_-|M55-family-metallopeptidase
MDNHGSTGEDPTSEAKGPRILISVDMEGVSGIVHPREAHPDGYDYGRARALMTAEANAAVAGVLDAEPGAEVWVADAHGSYRNLLPEEVDRRARLVRGKPRPLGMLGGIDERTDAVLFVGYHVRAGAGPGVLAHTMSDALLDVRVDGRSLGEIGLNAAMAGHLGVPVVLLSGDDAACAEVRELVPGVRTVAVKEALGQFAAAGLHPEEARERLRRTAAEAVAGREEVRPFALSGPQTVEVDLAAAHTVDLAVLIPGVTRAGGARTVTFTAPDFREAYRVVLLLVQLGSIRPA
>NC_020990.1|WP_015507761.1|4428899_4429754_+|alpha/beta-hydrolase
MSGASSRSSRSPGESRLPVHATVWDDRPNSGGSVSRWPVVLVHGILTWGTDPRYGFAAQRPLAARHRLLLMDRRGYGRSPDIARSDWAVDAEDIVELLGTGAHLVGHAYGGVGALAAAVRRPDLVRSLTLIQPGALRPAARHPVVAEALARARAATAALPPDLTPADFLRGATESVGMETPEATPERLRAAATTMAELPCWDAEIDLGPLARAAFPQLLVSGDWEGAPEPYRTYAGLPLIACAEEIAAATGAAHLVVPGHYPHTQQPERVNAAMEHLWEAADQG
>NC_020990.1|WP_037629598.1|4427865_4428765_+|acetylxylan-esterase
MPGGFAGFWRGRYEEALEVVTAPEVGAVEEVRDGVRVCRVSFGSVGGVRLGGWLALPVDGPAEHGFVVGHGYGGRDAPGPDLPLPLPRSAALLPCVRGMGERSRLPGVPSVADAHVLHGISSRDTYVIGACVADLWCAASALLELVPELARHPSGPRLGYLGESFGGGLGALALPWDDRFAAARLTVPTFGNHPLRLTLPCTGSGESVRRHHRDHPHVVDVLSYFDAATAATFVRVPTLVAAALFDPAVPPPGQFAVHNGLPDDLRALHVLSAGHFDHPGAEEETAGLARAEREFFTRL
>NC_020990.1|WP_010638599.1|4425999_4427250_-|sugar-ABC-transporter-substrate-binding-protein
MHRVARTATAVIAASTALAVVTACGGSSGTEVAADAEQTLTVWAMGAEGEKLAEVAKEYEKENPHLKVKVTPVGWDVAHQKLVSAAAAGNLPDIAQMGGSYLGEFAELGVLEPVDTKRFQEKDFFPAGWQQGEVDGEVYGVPWYVDTRVLYYRTDLAEKAGVDKAPADWKELRALASAYQKDAGTKWGLSIQPSGLDTVQSFYPFLYSAGGEIIDEDGKVVVDSPAAVKALKEYGAYFDKGLANKSVPPGYDVVKDFGNGRVPMFFGGPWHVTLLNEGQPDIKGKWAVAEVPADEASVSMAGGSSLTVSKDSPHKAAAEEFIAHLTSTEGQADWYERTKDLPANTTAWESGSLADDPALKVFEKQMKTAKASPTLANLSEITDKVDQAIAQVTQGKATAEEALGKAKDQIEGLVQK
>NC_020990.1|WP_003948480.1|4425043_4425994_-|sugar-ABC-transporter-permease
MSTTTRKADEAAPGGRRPGRRRGSLGVQNAAGWLFSTPFLVLFAVFMAFPIVATLLMSFTDFGLGNVTRPLDARFIGFENYTRLFGDERFLKSLFNTAYFVVVGVPLTIGLGLLVAVLLNNGIDRARTFFRVGFYAPVVTSIVAVAVVWRFVLDPSDGLIAGLASEVGLTAPDFLGSEALAMPSLIAMAVWRNLGTVMVLFIAGLQAIPTEVREAARLDGVGPWQELRRITIPLLRPTLLYASVITTIGYLNVFEEPFVMTQGGPSDSTLTVSLNMYREGFNFFHMGYASAMAYVLFVVIMGITVLQLRLLKDNTR
>NC_020990.1|WP_003948481.1|4424213_4425047_-|carbohydrate-ABC-transporter-permease
MSAEGRVRRPLTYVLLSGGLLVMAAPFLWMGLSAFKTQRELSASPPVWIPSQWTLANFRQLLADLDLPLYFMNSVIVAVLVTVSNLVFCSMLGYALAKLNFAGRNKVFGVVLGALMVPGNLMLLPLFVLMSKLQLIDSYAGLVLPFAAGAFGVFLMRQFMQSIPDELLEAARMDGAGEWFIFWRIVMPLVKPALATLAILTFLGSWNNFVWPLIATNDPDKYTLPVALATFATDPNKAGGSNGVLMAGSFLIVLPVLAVFIALQRHFTQGIATAGMK
>NC_020990.1|WP_015507759.1|4422952_4424146_-|family-1-glycosylhydrolase
MTSTPFPEGFLWGASTAAHQIEGNNTDSDWWVKEHTAGTHIQEPSYDACDSYHRWPEDMDLLASLGFTDYRFSIEWARIEPVEGHFSRAELAHYRRMVEGAIERGLRPMVTLHHFTVPQWFEARGGWTAEGATELFARYVAACAPVIATGVAHVCTINEPNMIAVMAGQAKRGDIGFPPAGLPTPDEETTHAVIAAHHAAVKEVRAISPEIKVGWTIANQVYQALPGAEEVTAAYRHPREDVFIEAARGDDWIGVQSYTRTRIGADGPIPASPEAERTLTEWEYYPTAVGHALRHTAEVVGDVPLIVTENGIATADDQRRTAYYTGALGEVAAAIEDGLKVEGYLAWSALDNYEWGSFRPTFGLIAVDWETFERTARPSAVWLGSLGRTRELPGRAV
>NC_020990.1|WP_003948483.1|4421335_4422856_-|VCBS-repeat-containing-protein
MAWMRRPDTPTTRRGRSGRAAASLAAALLVSGGLSAAALAPTTALAADGPAAASADDFNGDGYADLVSGAPGGTVSGKAGAGYVAVTYGSAKGLAPAPGTVVSRSTAGVPGAATAKQRFGETFAKGDLDGDGYSDLVIGSATAEPGAVILWGSPKGLTGGTAVAGFGQAPQVGDFDGDGQADLALFGAAQVAGDDPVTQEARLFKGPLTREGTPAEQLDFLDRSEWWGYDSDGPACAEDDSCVDGPTSVGGPVRPKAVGDVNGDGSDDLVTWLYEGDGVWAHHLFTGSATGFRDAQEAGPIGSSGDDAAVGVGDVDGDGYDDVVTGSGEATAKVTVRYGSAAGLEGREQAFDQSLPGLHGAQEKGDHFGSCVAVADVTGDGRAEIALGISGEDFSGLTDAGSIALLHGTASGVTGEGSQVLHQNTAGVPGVAESGDKFGSACALLDTDGDGHRDLVAAAAEENEQAGAVWALRGTGEGLTVEGASAFGPGHVGGPVTKAKFGSFLR
>NC_020990.1|WP_003948484.1|4420810_4421275_+|VOC-family-protein
MAEKSFPAPESGMLLSYFLTVADVPRSRAFYSEVLGGEVILEENPCTVRLANSWLIMNPGGGPTPDKPGITLHPPEDPATATCFLNIRVADIQAVYEEWSAKGAEFVTPPIDRKAEIRCYLRDPDGYLIEIGQATGMLHGVYADPPAGKGPGTR
>NC_020990.1|WP_003948474.1|4432462_4432675_+|hypothetical-protein
MLTTTRPRTTPVPPPCPDRACHTDIHGRLWKDTTYLRNDPDNWRWYCSRCGQHWMPTHKQFAWYRTLPVA
>NC_020990.1|WP_003948473.1|4432806_4433364_-|carboxymuconolactone-decarboxylase-family-protein
MTTENTPTAPSTSTTPTTSTTPDEKAAAYLPEHTPRISVAELAPDLYRALARADAAARKNLDPVIGELVKIRASQINHCAFCLDMHTKDALAMGESVERIVQLSAWEESKHYYTAKEIAAIELTEAITVLTDGFVPDEVYAQAAEHFDENELAHLIGAITVINAWNRLSVAARNVPGHYVPGSLG
>NC_020990.1|WP_003948472.1|4433470_4434898_+|PLP-dependent-aminotransferase-family-protein
MTESWANLGIDLHLEPAGPGLRKGLTDALREAVRSGRLAPGTRLPSSRTLAGDLGIARNTVADAYADLVAEGHLTARQGSGTRVAEQAGPASAVPRRQRPVRVPERAGPAHDLTPGTPDLSAFPRAAWLKAARRALTAAPNDAFGYGDPRGRPELRAALAEYLARVRGVAADPERIVVCAGVAHGLKLVTEVLAARGGHGGRQGAGTVAVETYGLRFHREWLAEEGVGTVPLPFDADGTDPAGLDGERAVLLTPTHQFPMGGTLSPARRAAVVDWARRTGGLILEDDYDGEFRHDRRPVGALQGLAPDRVAYFGTASKGLAPGLRLGWLVLPPALVDEVLAAKGYADTCGAPDQLTLAEFLTSGAYDRQVRLMRLRYRRRRDELVATLARRAPSVRVGGIAAGLHAVLLLPPGTESEVLRAAAWHGLGVQGLSWFRHPDAEAAGRPVPEGLVIGYGRPPDHAWQSALETLCRCLP
>NC_020990.1|WP_003948471.1|4435182_4435761_+|hypothetical-protein
MAENITVPAVRALDAPVARPATGPGRGAAPQEPPVADERLPVPVRLTKSGAGEPGSGSGEPSAEQRRKKAARRRVRSSTVALGSMGVLAAALAACGSEPDRRCVDRNSYSYGGGYKVVDSSQCRNGSSGSTGGTGGGGSSGGSGRYGSDRNSNAGWYYGGDSKSGYASDGSFNKSSVSSGGFGCSGKGSGGG
>NC_020990.1|WP_003948470.1|4435904_4437125_+|glutathionylspermidine-synthase-family-protein
MQRHTIEPRPGWQETVEAQGVIYPLTRHPDDSLRPYWDESAYYSFSLAEVEALEEVVEELHAMCLAAAAHIVEKDRFAELGITDPRLASLVTEAWHRKAELPSLYGRFDLWYDGSGAPAKMLEYNADTPTSLVEAASAQWFWMEERFPGADQWNSLHERLVDAWRAQAALLPPGSPVHFAHTIDDECGEDLMTVAYLRETAAQAGLETEAIAVEDIGWDSLSHRFVDQRLRFIRSCFKLYPWEWLATDDFGPHVLDTLDNGGGTGSTLWIEPAWKMLLSNKALLAILWELYPGHPNLLASYLDGPRELATTTGYVTKPLLGREGAGVTLHQPGGTQTPAPATGPSCYQQLALLPDLSTPAPGAHSPTNHVVLGAWVVADEAAGLGIRESAGPVTDGYARFLPHVIL
>NC_020990.1|WP_015507763.1|4437168_4437702_+|GNAT-family-N-acetyltransferase
MPELQRLRADHAPALLAFERENRAWFARTISDRGDAYFADFPARHRALLTYQDEGTDHFHVLVADDATTILGRFNLMDITDGQAELGFRMAESATGRGLATEAARTVCHLAATAYALTSLRAQANLGNLASHTVLTRTGFTATEQTVLRNGTAGRRYVKELAGPEEGAAGAIGAAGL
>NC_020990.1|WP_003948468.1|4437715_4438969_-|ornithine--oxo-acid-transaminase
MSGTPSGTHSSPAPGSATAEAIDAAEAHSAHNYHPLPVVVASAEGAWMTDVDGKRYLDLLAGYSALNFGHANPRLIAAAKAQLDRVTLTSRAFFHDRFAAFCEELAALCGKDMVLPMNTGAEAVETAVKTARKWGYRVKGVPDGAARIVVASGNFHGRTTTIVSFSTDEEARADYGPYTPGFDVVPYGDADALEAALTDDTVAVLLEPIQGEAGVLVPPAGYLRRVRELTAERNVLFIADEIQSGLGRTGRTFACEHEGVVPDLYLLGKALGGGVVPVSAVVGDSDVLGVFRPGEHGSTFGGNPLACAVALEVIAMLRTGEYQARATELGTRLHNALADLVKADGPVRAVRGRGLWAGVDLDPAVGTGREISERLMSRGVLVKDTHGSTIRIAPPLVISAEDLDWGLGELRGVLGMA
>NC_020990.1|WP_003948467.1|4439325_4439823_+|hypothetical-protein
MSALDFCAEVLIEGRIRGAGLGDSMAVWDRCMGYEYTDGLSRGRLRRDYGLVEIIFEQYDTGWHATGIEIQAYRLGRFGVGIVPQVLAPYFGAVESRVNAKELLETVAAKGFGIEAVHEEGARTHAYRVDSSGGVVYVLMAETRSMKVPSVGDVWTVVLELPDEE
>NC_020990.1|WP_008410798.1|4440259_4441087_+|trypsin-like-peptidase-domain-containing-protein
MKKPLAGALLAAALLGASAAPAVAAPGPAAPAAVDLAGTVALSNCSGSVVRAPSASADDPALVLSNGHCLETGFPAPGEVLVDQPSSRSFTLLDGAGNGVGTLRAAKLAYGTMTDTDVSLYQLGESYAEIESAYGIEALELDAARPSEGAAITVASGYWKRTYNCSVDGFAHQLKEGSWTWKDSVRYTDACDTIGGTSGSPVIDDATGKVVAVNNTGNESGGRCTDNNPCEVDENGEVTVREGINYGQQTYTLVPCIGPGSEIDLGREGCAVPKP
>NC_020990.1|WP_003948464.1|4441180_4442017_-|DUF1206-domain-containing-protein
MNSSSMAREGHRQARRAADSKVVSAGARAGFAARGVIYLLVGLLAGQIAFQGDGKQADRGGALQEISGQPFGGILLWVIGIALVGMALWRLSEAAFGAAGPDGDKAMKRVVSGARAVFYAFVAYSVLSFAAGEKSGGGSSDKQSQDITAQALGLPGGQWIVGVAALGVAVAGVVVGARAVMRKYHKHLRMGAMSRRARQFVDVTGVFGGAARGLVFAAAGVFAVTAAVDYDPDEAKGMDDTLRSFADTPAGPWLLVLVAVGLAAFGLFSFANAKWRKV

Crispr_ID: NC_020990_25

• CRISPR_ID: NC_020990_25
• CRISPR_location: 4569969-4570056
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_25

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NC_020990_25

>25.1|4569992|42|NC_020990|CRISPRCasFinder
GTGGTGGGTAGTTCCGTACGGTTCGAAGGTGCTGGTTCCTGA

CRISPR arrays and Neighbor proteins around NC_020990_25

CRISPR arrays

The CRISPR arrays of NC_020990_25

>merge|NC_020990|25|4569969-4570056|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGTGGTGGGTAGTTCCGTACGGTTCGAAGGTGCTGGTTCCTGATGGCCTCAAGCGCCGGCCGGGCT

>NC_020990|25|20|4569969-4570056|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCT	GTGGTGGGTAGTTCCGTACGGTTCGAAGGTGCTGGTTCCTGA
TGGCCTCAAGCGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_015507804.1|4568616_4569864_+|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NC_020990.1|WP_003948339.1|4578064_4578754_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NC_020990.1|WP_003948354.1|4561351_4563124_-|ATP-grasp-domain-containing-protein	unknown	unknown	gnl|CDD|227111
NC_020990.1|WP_015507807.1|4578864_4579908_+|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176186
NC_020990.1|WP_003948348.1|4567659_4568544_+|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl|CDD|223417
NC_020990.1|WP_015507806.1|4572599_4574141_+|histidine-ammonia-lyase	unknown	unknown	gnl|CDD|236484
NC_020990.1|WP_003948340.1|4576511_4578011_+|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|223650
NC_020990.1|WP_003948336.1|4580561_4581665_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507808.1|4579933_4580467_-|DinB-family-protein	unknown	unknown	gnl|CDD|368218
NC_020990.1|WP_015507803.1|4565493_4565700_-|acyl-CoA-carboxylase-subunit-epsilon	unknown	unknown	gnl|CDD|379386
NC_020990.1|WP_050777408.1|4563564_4564059_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948341.1|4575126_4576386_+|L,D-transpeptidase	unknown	unknown	gnl|CDD|380079
NC_020990.1|WP_003948352.1|4564615_4565215_-|septum-formation-inhibitor-Maf	unknown	unknown	gnl|CDD|178901
NC_020990.1|WP_003948343.1|4574392_4574707_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948356.1|4559767_4559917_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948346.1|4570142_4570931_+|enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|181069
NC_020990.1|WP_003948355.1|4559989_4561072_-|hypothetical-protein	unknown	unknown	gnl|CDD|271332
NC_020990.1|WP_003948349.1|4565728_4567336_-|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NC_020990.1|WP_008411123.1|4559026_4559602_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NC_020990.1|WP_015507805.1|4571331_4572513_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|128563

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_015507804.1|4568616_4569864_+|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	4.77436e-29
NC_020990.1|WP_003948339.1|4578064_4578754_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	8.77408e-105
NC_020990.1|WP_003948354.1|4561351_4563124_-|ATP-grasp-domain-containing-protein	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NC_020990.1|WP_015507807.1|4578864_4579908_+|NAD(P)-dependent-alcohol-dehydrogenase	gnl|CDD|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NC_020990.1|WP_003948348.1|4567659_4568544_+|biotin--[acetyl-CoA-carboxylase]-ligase	gnl|CDD|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	2.5269e-61
NC_020990.1|WP_015507806.1|4572599_4574141_+|histidine-ammonia-lyase	gnl|CDD|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
NC_020990.1|WP_003948340.1|4576511_4578011_+|FtsX-like-permease-family-protein	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	4.54535e-16
NC_020990.1|WP_015507808.1|4579933_4580467_-|DinB-family-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	3.17423e-41
NC_020990.1|WP_015507803.1|4565493_4565700_-|acyl-CoA-carboxylase-subunit-epsilon	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	1.28735e-11
NC_020990.1|WP_003948341.1|4575126_4576386_+|L,D-transpeptidase	gnl|CDD|380079	pfam17964, Big_10, Bacterial Ig domain. This entry represents a bacterial Ig-like domain found associated with transpeptidase domains.	1.95752e-72
NC_020990.1|WP_003948352.1|4564615_4565215_-|septum-formation-inhibitor-Maf	gnl|CDD|178901	PRK00148, PRK00148, Maf-like protein; Reviewed.	1.30384e-95
NC_020990.1|WP_003948346.1|4570142_4570931_+|enoyl-CoA-hydratase	gnl|CDD|181069	PRK07657, PRK07657, enoyl-CoA hydratase; Provisional.	1.83306e-71
NC_020990.1|WP_003948355.1|4559989_4561072_-|hypothetical-protein	gnl|CDD|271332	cd14962, NHL_like_6, Uncharacterized NHL-repeat domain in bacterial proteins. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	0.00217291
NC_020990.1|WP_003948349.1|4565728_4567336_-|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NC_020990.1|WP_008411123.1|4559026_4559602_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	9.07031e-11
NC_020990.1|WP_015507805.1|4571331_4572513_+|GGDEF-domain-containing-protein	gnl|CDD|128563	smart00267, GGDEF, diguanylate cyclase. Diguanylate cyclase, present in a variety of bacteria.	3.44277e-39

Protein sequences

>NC_020990.1|WP_015507804.1|4568616_4569864_+|adenylate/guanylate-cyclase-domain-containing-protein
MTVDDTGSGTGTPRGPHGRDTGGGAGASDSAAPDGAAPGGGRGPVSGAPERGLPDLPDRSEHGGEPQEDGGQTEPKQDPLALRIEGLILGAERRYTPFQAARAAGVSMELASRFWRAMGFADIGQAKALTEADVLALRRLAGLVEAGLLSEAMAVQVARSTGQTTARLAEWQIDSFLEGLTEPPEPGMTRTEVTYPLIELLLPELEEFLVYVWRRQLAASTGRVIQVADDEEMVDRRFAVAFADLVGFTRLTRRMEEEELGELVEAFETTAADLVAARGGRLVKTLGDEVLFAADDAGTAAEIALLLIETMANDGSMPELRVGMTFGTITTRMGDVFGTTVNLASRLTSIAPKNAILVDSAFAAELVRTGEAPASEAEAAAAEEPGEYRFALQPMHQRPVRGLGAVEPWLLTRRD
>NC_020990.1|WP_003948348.1|4567659_4568544_+|biotin--[acetyl-CoA-carboxylase]-ligase
MTPTDRPGRNGPAPWSDLSRPPLHESALRRALVRPGGLWTSLDVVQETGSTNADLAARAPELPEGTVLVAEEQLSGRGRLDRRWSAPARSGIFFSVLLRPTAPVEKWGWLPLLTGVAVASAVSRIAGVDTGLKWPNDLMVTVGDEERKAGGILAEMAGGGIVIGVGINVTLRADELPVPTAGSLGLAQAAVTDRDPLLRAVLRSLEEWYGRWQEAGGDAAASGVQAAYAAGCVTLGRAVRAELPGGEALTGEAVALDAEGRLVLATRDGVQRPVGAGDIVHLRPDGPPEGSGGE
>NC_020990.1|WP_003948349.1|4565728_4567336_-|acyl-CoA-carboxylase-subunit-beta
MSAPENATTPPNPELHTTAGKLADLQRRIEEATHAGSARAVEKQHARGKLTARERIGLLLDEGSFVELDEFARHRSTNFGLEANRPYGDGVVTGYGMVDGRPVAVFSQDFTVFGGALGEVFGQKIIKVMDFALKNGCPVIGINDSGGARIQEGVSALGMYGEIFRRNTHASGVIPQISLVVGPAAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNATSGVAHHMAGDEKDAIEYVKSLLSYLPSNNLSEAPVFAEEADLETSDEDRELDVIVPDSANQPYEMLRVIEHVVDDGEFLETQALFAPNIVTGFGRVEGHPVGVVANQPMQFAGCLDIDASEKAARFVRTCDAFNIPVLTFVDVPGFLPGVDQEHTGIIRRGAKLIYAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTLAQTPAEELEAVRTRLIQEYEEALLNPYTAAERGYIDAVIMPSDTRSHIVRGLRQLRTKRESLPPKKHGNIPL
>NC_020990.1|WP_015507803.1|4565493_4565700_-|acyl-CoA-carboxylase-subunit-epsilon
MMIKVVRGNPTPEELAAALAVVRARAASAPGSDEGPRPPEGWSDPARVARTRMPAPGPRSWARTFWPS
>NC_020990.1|WP_003948352.1|4564615_4565215_-|septum-formation-inhibitor-Maf
MSNRRVVLASASPARLGLLRQAGLAPEVIVSGVDEDALTADSPGALALVLAEAKAAAVALRPEAAGSVLIGCDSVLDLDGVALGKPADAEDATARWKAMRGRNGVLRTGHCVIDTASGRRASATASTTVRFGEPSDEEIAAYVASGEPLHVAGAFTLDGRSAPFIDGIDGDPGNVIGLSLPLLRRLLTELDLAITDFWE
>NC_020990.1|WP_050777408.1|4563564_4564059_+|hypothetical-protein
MAAVAAGVVLFAEAFGVFMLLMTVGIVVENQSMSLDGLDPAMMSGGALGFGIFSAVFLAGCGLVLLLVGVRDRAPARFARILLVVVAVVHGVLGALTVGLVGWEAFAVLMVVLALIVFTLVAYGPGGRPQKPEAQQGAGSEQGEERTQKQEPFPGEPGPKPAAS
>NC_020990.1|WP_003948354.1|4561351_4563124_-|ATP-grasp-domain-containing-protein
MRKVLIANRGEIAVRVARACRDAGIESVAVYADPDRDALHVRAADEAFALGGDTPAASYLDIAKVLQAAADSGADAIHPGYGFLSENAEFAQAVLDAGLTWIGPPPQAIRDLGDKVAARHIAQRAGAPLVAGTPDPVSGSDEVVAFAEEHGLPIAIKAAFGGGGRGLKVARTLEEVPELYDSAVREAVAAFGRGECFVERYLDKPRHVETQCLADQHGNVVVVSTRDCSLQRRHQKLVEEAPAPFLSEAQVEQLYSASKAILKEAGYVGAGTVEFLVGNDGTISFLEVNTRLQVEHPVTEEVAGIDLVREMFRIADGEELGYGDPVLRGHSFEFRINGEDPGRGFLPAPGTVTVFDAPTGPGVRLDAGVESGSVIGPAWDSLLAKLIVTGATRQQALQRAARALAEFNVEGMATAIPFHRAVVADPAFAPELTGSSDPFTVHTRWIETEFVNEIKPFDAPADGDAEDESGRETVVVEVGGKRLEVSLPSSLGMSLARTGLAAGAKPKRRAAKKSGPAASGDSLASPMQGTIVKIAVEEGQEVKEGDLVVVLEAMKMEQPLNAHRSGTVKGLAAEVGASITSGAVICEIKD
>NC_020990.1|WP_003948355.1|4559989_4561072_-|hypothetical-protein
MKQRPDRGARWGRLLAVTVVGALALFGPGSATAGAAGAPTEQPGTTELPYAYHSDLETDARHQRLYISDRVTGSVLVTDFDGRVVRKLDGLPGAADLALSKDNRTLYVALADGDAVVALDTATYRQKARYPTGEGTGPAQLALTGGKLWFSHGENWESNIGSLDLGGSKPVVRLNLTPEGYWGGPPRLTASPAAPGKLVAGEQYMSNAGVTVYDVGSGTPKPLVAQDNPGDLGALTGLALTPDGKSLLATGGYPYHHLSLDLGSLEVDHIYPTVAYPTASAVSARGAVAAGVNNSWGEDVYLFRQGESEPYRVVDFDPGTGSYLRPNGLAWSPDGTRLFAVTGTDGPHLSLRVVTAADPR
>NC_020990.1|WP_003948356.1|4559767_4559917_+|hypothetical-protein
MGGGLLMAGAAALASGTARLVAVVVVGVGAVAAWALYDHRTERRRGDSA
>NC_020990.1|WP_008411123.1|4559026_4559602_-|TetR/AcrR-family-transcriptional-regulator
MPTETDQRPLRADARRNRERLLVEARRAFAAHGTDTSLEEIARRAGVGIGTLYRHFPHREALLSAVFADAVGELLERARVLLEAERPCAALVEWLRSLITHASEYQGLSGALMSASSGTGSELSRCSDPMRDAGAALLGRAQEAGVVRPDISIGDLLQLTNAIALAAEATPDEPELADRLLSLTLRGIRPD
>NC_020990.1|WP_003948346.1|4570142_4570931_+|enoyl-CoA-hydratase
MPQTAEHLTITRHGHVAELALNRPEAMNAVSTDLARQLAAACEELARDQDVRVTVLTSTHPKAFCVGADLKERNRFTDAELVRQRPTARAAYTGVLELPMPTIAAVHGYALGGGYELALACDLIVADPTAVVGLPEVSVGVIPGGGGTQLLPRRVGAARAAELVFSARRVAGAEALALGLVDRLAEEGQDRAEALELATAMAAHSPVGLRNAKRALRLGQGLDLRAGLEVEDAAWRATAFSGDRAEGVAAFNEKRAPKWPGE
>NC_020990.1|WP_015507805.1|4571331_4572513_+|GGDEF-domain-containing-protein
MGDDLRLRAVVGLAQAMAAAQGPREVWRAAALGACRALGGSFAALSVWEREQGRLRVLVNAGRLAAGEEEYPEAETYPVHQFPEITEFLHERWAGGGEPDAWVETADGRAEGRPGYCHQRVAALRRRGRGCCVVAPIVLHGHAWGELYVARDAGAEVFGRADADFATVLAAVAAAGIVQCERLEEARRLAYTDALTGLANRRAVDARLDEAVEAHRAEGAVVSLVVCDVNGLKRVNDTHGHAVGDRLLERFGSLLSLCGAMLPGTLAARLGGDEFCLVSVGPGADEVVAVAEELCERAYGLATGEGVACGVASTGDAIGEVRSARRLFRLADAAQYRAKAVRARGPVVAGREAEPETGADAVLKLADTPPPEGGERRRLRGRRGGSGGAGAPG
>NC_020990.1|WP_015507806.1|4572599_4574141_+|histidine-ammonia-lyase
MDMHTVVVGTSGTSAADVVAVARDGARVALSPEALAALAHAREAVDALAAKPEPVYGVSTGFGALATRHIGPELRTQLQRNIVRSHAAGMGPRVEREVVRALMFLRLKTLCSGYTGVRPEVAQTVADVLNAGITPVVHEYGSLGCSGDLAPLSHCALALMGEGDAEGPDGTVRPAAELLAEHGITPVELREKEGLALLNGTDGMLGMLVMALADLDRLYTTADITAALTLEALLGTDRVLAPELHAVRPHPGQAASAANMAAVLAGSGLVGGHQDDAPRVQDAYSVRCAPQVAGAGRDTLAHARLVAERELAAAVDNPLVIDGRVESNGNFHGAPVAYVLDFVAIAVADLASIAERRTDRLLDKNRSHGLPPFLADDPGVDSGLMIAQYTQAALVSELKRLAVPSSADSIPSSAMQEDHVSMGWSAARKLRTAVDALARVLAVELYAATRAVELRAGLTPAPASAAVIAALRAAGVEGPGPDRVLAPDLALTTEFVRSGRPVEAAEQHTGPLA
>NC_020990.1|WP_003948343.1|4574392_4574707_-|hypothetical-protein
MSSTARRSLLTATTAATLLGALWFVPSANASGTAGDTAPQEERAATTAGSAAEPAGEELLLADSGSVDTTPYLVGGTAFLLVGAGFVAYSARRGPWVTEDAGLT
>NC_020990.1|WP_003948341.1|4575126_4576386_+|L,D-transpeptidase
MTDSKRRRALSAASALLGGVLVLTACGGGDDGGSGGGSSESREKSQAEVDEAAAKKTSAARIKITPKDGADNASINNDAEVSVTKGKLTDVSMKSADGTDVPGTFSADKTSWKPEGQLQRATVYKIAAEAADSEGRKAHENASFTTVSPDNSFIGNFTPEDGSTVGVGMPVSINFDKGITNKAAVQNGIKVSSSSGQEVVGHWFNEKRLDFRPEDYWAGNSTVTLKLDLDGVEGADGVYGVQQKTVTFKIARNQVSIVDAKTKTMKITRDGKTVKTIPISAGSPDNKTYEGRMVISEKFKETRMNGATVGFTDDDGKGEYDIKDVPHAMRLSTSGTFIHGNYWGDKSIFGNANTSHGCVGLADAKGANDASTPGAWFYNNSMVGDVVDVRNTGDKTIAPDNGLNGWNMDWAQWKAGSAV
>NC_020990.1|WP_003948340.1|4576511_4578011_+|FtsX-like-permease-family-protein
MFLTYLRRELRRRRKAALVVASGLALGIALVIVVTSVTAGMQRAQDQVLGSLYGLGTDLTVTKARSAPADGERPERPTFDFDADEDGEEQSGERLVVQGLATLDAATVTTAAAQDGVARAAGGLSLTSISVDGQFRRGQVQQDDSSDGSAAPPNGGPGGGGSGGPGGGSGGRVEGGGAAFGIDSFTVYGTDVTADGLGPLASSALTEGRAFTKADTDAAVAVVDSGYAQQEKLAKGDKVTVGGTKFTVVGIATADSGQAAADVYLPLKRAQTLADAKDKITTVYVQAADSQQIGTLKTALTKKLPGTTVTSSADLADTVSGSLSTAASLAGTVGRWLSWTVLAAAFLVAGLLTTASVGRRVREFGTLKALGWRSGRVTRQIVGEAVVNGLIGGVLGIAVGLGAAYAITAAGPTLTAQLGSLGGGMGGGGMGGGMGRGPGGGGGSGAGAQSLDVALTAPVSATTLALAVGLAVAGGLVAGAFGGWRASRLRPADALRRVE
>NC_020990.1|WP_003948339.1|4578064_4578754_+|ABC-transporter-ATP-binding-protein
MYRLSGVTKHYRRGKQTVAALDGVDLTLADGDRLVIQGPTGGGKSTLLQMLGGLDRPTSGTVELDGTDLAALPEARLTRVRAETIGFVFQSFNLIPTLTAQENVETALVPLGLRAADRRERAAEALASVGLGERVGHVPAELSGGQQQRVAIARALVKRPKVLLADEPTGNLDTATRDDIMELLDALWREHGLTFVMVTHDPALTRRADRLATLTGGSLALTENRADAS
>NC_020990.1|WP_015507807.1|4578864_4579908_+|NAD(P)-dependent-alcohol-dehydrogenase
MTQTVPAYAAPAPGAPLERTTIERRTPGPHDVLIDIAYAGICHSDIHQARDGWAEGIFPMVPGHEIAGTVAAVGEAVTRFSVGDRVGVGCMVDSCRTCEFCLAGQEQNCANGSTGTYNAIGRDGEPTYGGYATHVVVDENFTVRIPDSLPLDVAAPLLCAGITVYSPLRHWQAGPGKKVAIVGLGGLGHMGVKIAHALGAEVTVLSQSLRKREDGLKLGADHYHATADGTVFDELAGTFDLIVSTVSAPLKLGGYLKLLRPDGALVNVGAPEEPVSLNLFSLIGGRKTLAGSNIGGIPETQEMLDFCAEHGLGAEIEVIRADQINEAYERVVNSDVRYRFVIDTATI
>NC_020990.1|WP_015507808.1|4579933_4580467_-|DinB-family-protein
MSGIVVPVDGLAERVSPPVNGSERESLRGHLDFHRATLLAKCAGLTTEQLRTKSSPPSALSLLGLVRHMAEVERAWFRRTFAGEEIGLVWSPEGDFQVAYDAARADAGEAFAAWQAEVAHARRIEAAAASLDETAWSPRWEAEVSLRAIMLHLIHDYARHNGHADLLREGVDGAVGV
>NC_020990.1|WP_003948336.1|4580561_4581665_-|hypothetical-protein
MEILWALMAVVMIGAVLGPVILRRRRGIRQVQPGTPEAADPAQYGFRPQETLDLRLPGPDQDLLDVLDVVQRTQDWRAASQLLAGTDKHGELRWQRVQAFAGAASLELQQRPGEGGRWLRDWRAQEPKDAGGAAVHAEFLVQQAWRSSTAGSDDFRIILEEARSAVAQAALLAPGDPVPYISELAVARGLGYTQQEFDQLWLKILDRAPAHMGAHLVALPYWSEKWHGSRQQSMAFAEAAAARAPGGSLLSALPLFSLYEHLPEVNLVRNFFQSQVFTRALEGAQFAAQSARQDDPVLPHVRHLLVFFLVSSERWGEAMHQLVRVDGYVGALPWTLSADPAAQFAVYRALAVGGYEANGGSPATLRG

Crispr_ID: NC_020990_26

• CRISPR_ID: NC_020990_26
• CRISPR_location: 4884760-4884849
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: Cas9_archaeal

Consensus repeat of NC_020990_26

Consensus_repeat	Method
ACAGCCCGGCCGGCGGTTGAGGCCA	CRISPRCasFinder

spacers of NC_020990_26

>26.1|4884785|40|NC_020990|CRISPRCasFinder
AATTGGTGACCGGTACGGGCAAACCGGAGTCCCGCAACCA

CRISPR arrays and Neighbor proteins around NC_020990_26

CRISPR arrays

The CRISPR arrays of NC_020990_26

>merge|NC_020990|26|4884760-4884849|CRISPRCasFinder
ACAGCCCGGCCGGCGGTTGAGGCCAAATTGGTGACCGGTACGGGCAAACCGGAGTCCCGCAACCAACAGCCCGGCCGGCGATTGAGGCCA

>NC_020990|26|21|4884760-4884849|CRISPRCasFinder
ACAGCCCGGCCGGCGGTTGAGGCCA	AATTGGTGACCGGTACGGGCAAACCGGAGTCCCGCAACCA
ACAGCCCGGCCGGCGATTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_008414245.1|4884954_4885866_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NC_020990.1|WP_026048022.1|4876297_4877788_+|PHB-depolymerase-family-esterase	unknown	unknown	gnl|CDD|273828
NC_020990.1|WP_003948068.1|4896127_4897156_-|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|237845
NC_020990.1|WP_015507887.1|4881560_4883855_+|4-alpha-glucanotransferase	unknown	unknown	gnl|CDD|376788
NC_020990.1|WP_015507886.1|4877803_4880857_-|hyaluronidase	unknown	unknown	gnl|CDD|369423
NC_020990.1|WP_003948089.1|4870996_4872262_-|6-phospho-beta-glucosidase	unknown	unknown	gnl|CDD|133432
NC_020990.1|WP_003948073.1|4891236_4891596_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507884.1|4872334_4873624_-|ROK-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224851
NC_020990.1|WP_003948082.1|4881208_4881559_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948072.1|4891626_4891920_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948074.1|4890691_4891222_+|hypothetical-protein	unknown	unknown	gnl|CDD|379311
NC_020990.1|WP_003948067.1|4897492_4900813_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173796
NC_020990.1|WP_037629494.1|4890071_4890551_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948070.1|4892153_4893314_+|allantoicase	unknown	unknown	gnl|CDD|237319
NC_020990.1|WP_003948076.1|4889048_4889876_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_010637942.1|4883908_4884106_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003948087.1|4873828_4874893_-|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NC_020990.1|WP_003948086.1|4875288_4875867_+|HNH-endonuclease	Cas9_archaeal	cas9_archaeal	gnl|CDD|224321
NC_020990.1|WP_003948069.1|4893401_4895978_-|aminopeptidase-N	unknown	unknown	gnl|CDD|274121
NC_020990.1|WP_015507883.1|4870028_4871006_-|kinase	unknown	unknown	gnl|CDD|225518

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_020990.1|WP_003948086.1|4875288_4875867_+|HNH-endonuclease	Cas9_archaeal	cas9_archaeal	2.6e-11	37.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_008414245.1|4884954_4885866_+|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.29595e-45
NC_020990.1|WP_026048022.1|4876297_4877788_+|PHB-depolymerase-family-esterase	gnl|CDD|273828	TIGR01840, poly3-hydroxybutyrate_depolymerase_A_precursor, esterase, PHB depolymerase family. This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation].	9.28141e-74
NC_020990.1|WP_003948068.1|4896127_4897156_-|aspartate-semialdehyde-dehydrogenase	gnl|CDD|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
NC_020990.1|WP_015507887.1|4881560_4883855_+|4-alpha-glucanotransferase	gnl|CDD|376788	pfam02446, Glyco_hydro_77, 4-alpha-glucanotransferase. These enzymes EC:2.4.1.25 transfer a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan.	2.45652e-161
NC_020990.1|WP_015507886.1|4877803_4880857_-|hyaluronidase	gnl|CDD|369423	pfam07555, NAGidase, beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.	2.78281e-138
NC_020990.1|WP_003948069.1|4893401_4895978_-|aminopeptidase-N	gnl|CDD|274121	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type. This family is a subset of the members of the zinc metallopeptidase family M1 (pfam01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site).	0
NC_020990.1|WP_015507884.1|4872334_4873624_-|ROK-family-transcriptional-regulator	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	3.99317e-32
NC_020990.1|WP_003948089.1|4870996_4872262_-|6-phospho-beta-glucosidase	gnl|CDD|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NC_020990.1|WP_003948074.1|4890691_4891222_+|hypothetical-protein	gnl|CDD|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	0.00232068
NC_020990.1|WP_003948067.1|4897492_4900813_-|S8-family-serine-peptidase	gnl|CDD|173796	cd04857, Peptidases_S8_Tripeptidyl_Aminopeptidase_II, Peptidase S8 family domain in Tripeptidyl aminopeptidases_II. Tripeptidyl aminopeptidases II are member of the peptidase S8 or Subtilase family. Subtilases, or subtilisin-like serine proteases, have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure (an example of convergent evolution). Tripeptidyl aminopeptidase II removes tripeptides from the free N terminus of oligopeptides as well as having endoproteolytic activity. Some tripeptidyl aminopeptidases have been shown to cleave tripeptides and small peptides, e.g. angiotensin II and glucagon, while others are believed to be involved in MHC I processing.	1.14446e-63
NC_020990.1|WP_003948070.1|4892153_4893314_+|allantoicase	gnl|CDD|237319	PRK13257, PRK13257, allantoicase; Provisional.	1.10439e-166
NC_020990.1|WP_003948087.1|4873828_4874893_-|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	9.00626e-38
NC_020990.1|WP_003948086.1|4875288_4875867_+|HNH-endonuclease	gnl|CDD|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	4.21562e-21
NC_020990.1|WP_015507883.1|4870028_4871006_-|kinase	gnl|CDD|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	3.30208e-21

Protein sequences

>NC_020990.1|WP_010637942.1|4883908_4884106_+|hypothetical-protein
MVAGTTLTTLLMTSPALALTRDDGDDPGPGLSVVETLGLYVALPIVLFLVIAGLVMVMDKSGKRS
>NC_020990.1|WP_015507887.1|4881560_4883855_+|4-alpha-glucanotransferase
MALSRLAELHGVATSYSPSPDRTVPAAESAVVAALAALGVDASSPEAIRAALEKAEAGQAARLLPPTVVLRSAAPSADPRTAPELAALPPGTRVRLTRDPDPVPARPAPAGGRDAGEAVRRAAPVGEAPPPAWNWTVPLVPAATAPPPPAGSALPPAADVLWAVPFGVHRIEATTPDGRTATSHLVIAPDHIRGPESRAWGLLVQLYSLLSHRSWGMGDLGDLAELATWAGRVHGAGFVQVNPLHAAVPGTPTDPSPYRPSSRRFPDPVHLRVEAIPEYTALSADVRPHLDGLLRRAAELRGRVLSGEALIDRDAVWELKREALERLCAVPLPPGRQAAYEDFTAAHGQALTDHATWAALTERHGPHWSEWPAPLTDPRSRQTAAARTELAARVDFHRRLAWYTDTQLAEAQRAAREAGMAVGLVHDLAVGVHPDGSDAWSQQDVFAAGMSVGAPPDAFNALGQDWGLPPWRPDRLAESGYAPYRGLLRSLLRNAGALRIDHVMGLFRLWWVPVGAPPTDGTYVHYDAEAMLAVLALEAHRADAVVIGEDLGTVEPGVRETLQRHGVLGTSVLWFERDWDGTGLPLPAEAWRASCVATATTHDLPSTASRLTGDHVRLRHRLGLLTRPLAEEEAEEAAATATWLTVLDGLGLMGAAPGGHLPGAAPDEEAAVLAVHRFLLRTPARMIGVWLPDGTGDRRPQNLPGTWDQYPNWRLPVADAQGHPVTLEQLTASPRVARLLRTVATEDQTPAPMVRTAPPDARPV
>NC_020990.1|WP_003948082.1|4881208_4881559_+|hypothetical-protein
MAASAHLLLSALSKRPELHDLPAIPSPTTLAGRPDDPFDPDTVDYSLVSHPDSGLEGSCAYGLSEPPLTSEPPLADAAPLTSEPPLPDTAPLTSEPAAAAAVVAEDALLGAVSSGG
>NC_020990.1|WP_015507886.1|4877803_4880857_-|hyaluronidase
MQLRRSRTAAALAVAVIAGTLGGAPTALAAPPAPDPATAADEAPDDAKGETAGLPSVWPRPQSLRAADGKVALGSRVVLVAPLGTDPYALKALREVLREAGVRDVDEVSAEGDVPAGATPVVRVGGESAARPGAGGAGLEKTLRALGASARGDLPQGGYRLAAGQAGGRPTVAMAGVGEDGLFHAVQTLRQLVRDGVVPGVVVRDWPGTPVRGLSEGFYGTPWTTEQRLGQLDFLGRTKQNHYLYAPGDDLFRQARWREPYPAGQRAAFRALAERARENHVTLAWAVAPGQAMCLASEDDVKALNRKIDAMWALGARAFQLQFQDVSYSEWHCGEDEAEFGSGPAAAARAQARVANAVAAHLAERHPGSRPLSLMPTEYYQKGATEYRRKLAAELEADVQVAWTGVGVVPRTITGRELAGTREVLGHPLVTLDNYPVNDYAQDRIFLGPYTGREPAVATGSAALIATAMEQPAASRIPLFTSGDYAWNPKDYRPMESWQAAMDTLAGEDPETREAVRALARNTASSVLGADESAYLRPLLAKFWATRADAARAAGRPGTEAADAAARAAKELRAAFSVMRATPERLDGGGSGLGEEVRPWSEQLARFGHAGELAVDLLAAQARGDGTAAWHAERALRAVRAETSRNKVTVGDGVLGPFLDQVEKTADSWHGTVGGDGEKVADTGSAYTVALPRVRPLAGVTVRTDPGVSGLVEARVPGKGWQPVTRLEPGGWTDVESRGLRADALRVTGPEAERVDRLVPWYEDGAEAALRLGRGEADAEIGGGTSEVTARLTAHRPGTVRGALKAKTPKGIQVSAPGESVLPRGTEVRIPVSVRVADGVRPGSYEVPVEFGGRSATLTVRAFPPTDDRDLVRSGKATSSADETEDFPARAAADGDPESRWSSPAEDNAWWQTELPEPARVGRVELHWQDAYAAAYRVQVSEDGRIWRTAATVKDGKGGRERVGLDAKNVRFLRVQGDKRATEYGYSLFSVEAYAVTEKEKSKDQDKGKGEEKPGRD
>NC_020990.1|WP_026048022.1|4876297_4877788_+|PHB-depolymerase-family-esterase
MVTLAGVAGPESVTAPARAASLTEVTGFGSNPGNLRMFRYVPDGLPAGRPLVVAMHGCTQSAGGFDDETGWTKWADQWGFALVLPQQQSANNLNSCFNWFEAGDIRRDAGEALSIKQMTDRMKADVGSDPARVHATGLSAGAAMTNVMLAAYPDVFASGAPVAGLPYACATSVVAAYSCMNPGSNLTPAAWAAKVRDAYPGYAGPWPAVSVWQGTTDTTVVPANLTETVEQWTAVHGTDTTPDATGTVGGYPHAVYRDGDGRDVVETYTITGMGHGQPVDPGSGAEQCGTAGAYILDVNICAAYHIGRFWGLAEDGGGTDPGTPAQRAVIPSTAADDGYVKASASGTGAAVGALEGTMGAAVGRGTDGQHNRTLLSFDTSAVPDDATITRAYVTVSRAGGSGDPWAGGNRLLIDVRSGCFGASCATAADDWAAPATASGAAELARFTSGSADSTAFTEVNRTGPTQLRLRLADAPASTAYLFLRTGAEAKLTVEWE
>NC_020990.1|WP_003948086.1|4875288_4875867_+|HNH-endonuclease
MPHVLVLNASYEPLGVVPLRRALVLVLESKAVCLEESGAFLHSESRTVPAPSVVRLKRFVKVPYRGPVPLTRRALFARDGGRCVYCGGVATSVDHVIPRSRGGLHVWDNVVASCRRCNHVKADRHLMELGWRLRNKPAPPTGLAWRIIGTGHRDPRWLPYLQPFGGDDALARIENVGAGGEAVAVRPARAGA
>NC_020990.1|WP_003948087.1|4873828_4874893_-|mechanosensitive-ion-channel-family-protein
MFPSAPAAGREDTVTLEEAQERATDAAGWVSENWSTWLETGLRILLIIVVAAALRMVIRKTITNLIDRMNRTASAVDGTALGGLLVNAERRRQRSQAIGSVLRSVASFLIVGTAALMILDTFKINLAPLLASAGVAGVAIGFGARNLVTDFLSGVFMILEDQYGVGDTIDAGVATGEVVEVGLRVTKLRGPNGAVWYVRNGEVKRIGNLSQGWSTAAVEVTVRSDEDLDKVRDTLTEVGAQIAKDEPWNERLWGPVEVLGLDSVLLDSMVVGVSAKTMPGQDVAVERELRWRIKKAFDAVGISIVGGPAELTEEDAADPSAGMAAPSAYASATSPQSLAASPIPPPASGPRLGK
>NC_020990.1|WP_015507884.1|4872334_4873624_-|ROK-family-transcriptional-regulator
MVAGTPRVLRVMNERATLDLLTEHGALSRARIGALTGLSKPTVSQLLARLEAAGLVGPAGTSEGRPGPGARLYALRGEVAYVAALDVRPGRIRAAVADVTGTVLATHTLATPARPGPGGVPAQLTAALDGAARAAGTERPALRRVVVGTPGAFDPRTGRLRYAGHLAGWHSPGLLAEVAAALHPVPVEYENDVNLAAVAERRLGAARGHEDFVLLWNGTGLGAALVIGGRLHRGWTGGAGEIGFLPVAGTPLVRGVARTGSGGFQELAGAQALPRLAGELGVAVPQAGPEGADPADGEAVAAALLRTAAEAYTRPGGDPAPRAAEPPHEGTSSPHAGPAALLRAYAVRLATGIASLVAVLDPAVIVLTGRVLAAGGEPLLRLTEAELAELAPSRPRLLAGEVTGDPVVRGGLEAALTTVRDEVFDTAAL
>NC_020990.1|WP_003948089.1|4870996_4872262_-|6-phospho-beta-glucosidase
MKLTVVGGGSTYTPELIDGFARLRDTLPLTELVLVDPDAGRLKLVGGLARRIFARQGHPGTITTTGDLDAGVEGADAVLLQLRVGGQAARQRDESWPLECGCVGQETTGAGGLAKALRTVPVVLDIAERVRRTNPDAWIIDFTNPVGIVTRALLQAGHKAVGLCNVAIGFQRKFARLLDVAPAEVHLGHVGLNHLSWETSVRLGGPTGEDVLPRLLTEHGDAIAADLHLPRPLLDRLGVVPSYYLRYFYAHDVVVDELRTGPSRAEKVAAMERELLELYADPALDEKPELLSQRGGAFYSEAAVDLAAALLGRGGSPLQVVNARNDGTLPFLPDDAVVEVQAEVGPEGARPLAVPALDPLYAGLVQHVTAYEDLALRAALEGGRDRVFAALLAHPLIGQYDQAETLTDLLLSHNQEHLPWA
>NC_020990.1|WP_015507883.1|4870028_4871006_-|kinase
MGLSGAVLAIDAGNSKTDVAVVTADGEVAGTARGGGFRPPATGVEAAVDTLAEAVARAQDAAGHLPVAQVSACLANADLPVEEEQLSAAIAARGWGASVEVRNDTFAVLRAGLLEDAAPRGVAVVCGAGINCAGMLPDGRTARFPALGRVSGDWGGGGGLAEEALWHAARAEDGRGAPTELARALPEHFGLGSMYALIEALHLGHVPAGRRHELTPVLFTVAEAGDPVAAGLVERLAEEVANMAAVALGRLGLLDSPAPVVLGGSILAARRPGLDAGVRGELGRRAPLAEVRVVEAAPVLGAVLLGMDAVGAGVGAYERVRGWFG
>NC_020990.1|WP_008414245.1|4884954_4885866_+|LysR-family-transcriptional-regulator
MAPPAPEWDLRKLRILRALHQHGTVTATAEALLMAPSAVSQQLSNFARQLGVPLLEAHGRRVRLTDAAHLVLHHADEVFAQLERADADLAALVRGDAGQVRIGAFSTAVAALVVPLVTRLREEAPGLELRVREAEAGEAYDLLAAGEVDLALSLAAHAPTVRDPRFTRVPLLADPLDVALPSAHPLAGAPDLRLADLAADPWIYGADGPWSDITRAACEAAGFRPEQAHTATGWPAILALVGAELGVALVPRMVSAEYTPGSVVVRPLEADRPRRHVIAAVRRGAEQGGGPVARVLAALRAGA
>NC_020990.1|WP_003948076.1|4889048_4889876_+|hypothetical-protein
MRSPKRGPVAAPWLLFYSRYAGFMDMNGDKLNPGAIIDLTNWAELENADGSAFPVTPAKLHDLTSGDFLKVTSSLSHLYHALLNDGVVYSATAPAFRYVAALLGDRESRAALTPPWDGDKFPLRGKLLSWLADVAFDVSIEHEQRIREWGGYSPTEPFPDFLNIRSIYPEAFPGVASYFDDLDPRVVEAALVAAVRFLESPALAVHRGRLTFLLENVLAQSSSERHRSLASEALASWEQGRVLMEPFTDPHPSEEHGKDHRHSHGKQGSVDEPPF
>NC_020990.1|WP_037629494.1|4890071_4890551_+|hypothetical-protein
MVEAECMTDGSSYGSRPEYLPDFMNDPHDDDGRQVVKLDLAENRALAAATLSRFPAATGDVIDFESTPFEGRLWWDDEEHWTRMAADLLSSHVQRGERIAVIWGNYLMPVVAMPADVAVRRARDILDAGPHFWMHPLGGSVLIECLMDGQVTVATIPSS
>NC_020990.1|WP_003948074.1|4890691_4891222_+|hypothetical-protein
MKPEDQRVILDLVTYPGSAPRGTPEDVLRHFGTDDGRALGLELLREAVAERDGGQVEMALIVADRFGLSPACLEPLITSCSADWHRAHEGVVSALGTLRSPASVRALQHLADWVPDYLDYDDSRAMGVKAVWALRRTPGPEAEEALWGLLASGSGDVREAAAKGLRSRGVSESEGT
>NC_020990.1|WP_003948073.1|4891236_4891596_+|hypothetical-protein
MELPVREEELQEIEELCSAATPGPWHVRTLNDDSAMNLVAVSTVPGAGAGERWPDFDHRDLVAATLVQHPRYVDVGDECWDENAAFVAMARDAVPRLVEEVRRLRALLADKDEGEGVSA
>NC_020990.1|WP_003948072.1|4891626_4891920_+|hypothetical-protein
MAAEEFGLRVASYGPLVGVRDDPSHTRARACVGPLIDSGRLDREGLHLVMPMVRNGVPPAGEEPSYRCYLWFLERGRGERTLVLVDVSERRLKARAR
>NC_020990.1|WP_003948070.1|4892153_4893314_+|allantoicase
MTTHPATPDSQDAHADDPHANDAAPYPGGDPYGDYRTHGVDFSATDLVDLADRRLGAGVIAANDEFFAQRENLLVRERAVFDPEHFGHKGKVMDGWETRRRRGAGPETPFPAPEEHDWALIRLGAPGVVKGVVVDTAHFRGNYPQRVSLQATAVEGNPGPEELLASDVKWEELLPPTPVLGHAANGFAFDVERRFTHLRLCQHPDGGIARLRVYGEVVPDPEWLGLLGTVDLAAVLNGGVYEDASDRFYSSPTQIIQPGTSRKMDDGWENRRRRVRDTNDWVRFRLAAQGVIRAVEIDTAYLKGNSAGWVALSARDGEDGEWYEILPRTRLQPDTPHRFRLATPATATHVRLDAFPDGGVARMRLHGELTEAGAAALADRYRRLAG
>NC_020990.1|WP_003948069.1|4893401_4895978_-|aminopeptidase-N
MPGTNLTREEAQERARLLTVDAYEIELDLSGAQDGGTFRSVTSVRFDSAEAGASTFVDLIAPAVHEVVLNGTALDVAAVFRDSRIALDGLLQGRNELRVVADCAYTNTGEGLHRFVDPVDEQAYLYTQFEVPDSRRVFAVFEQPDLKGTFTFTVTAPTGWTVISNSPTPEPEGDVWKFEPTPRISSYITALIAGPYHAVHSVYEKDGQRVPLGIYCRPSLAEHLDAEHIFDVTRQGFDWFQEKFDYAYPFAKYDQLFVPEFNAGAMENAGAVTIRDQYVFRSKVTDAAYERRAETILHELAHMWFGDLVTMEWWNDLWLNESFATFTSVACQAAAPGSRWPHSWTTFANAEKTWAYRQDQLPSTHPIMAEINDLDDVLVNFDGITYAKGASVLKQLVAYVGEDAFFAGVQAYFKQHAFGNTKLTDLLGALEKTSGRDLTTWAQKWLQTAGINVLRPEITTDADGTVTSFAVRQTAPALPAGAKGTAVLRPHRIAIGSYDLDDAGRLVRTGRIELDVDGELTEVPELVGTGRPAVFLLNDDDLSYAKVRLDEDSLAVVTAHLGDFAESLPRALSWASAWDMTRDGELATRDYLDLVISGIPKESDIGVVQSLQRQVHMAIEQYADPAWRPEGLARWTEFALEQLRAAAPGSDHQLAWARAFADTARTDTQLDLLEALLDGGETIEGLAVDTELRWALLHRLAATGRADEGAVDAELARDRTAAGERHAASARSARPTEEAKATAWASVVESDKLANAVQEAVIGGFVQYDQRELLAPYTAKYFAAVKDVAAGRSHEMVQQIVVGLYPALQISQETLDATDAWIAANDPTPGLRRMITECRAGVERALRAREADAAAGRA
>NC_020990.1|WP_003948068.1|4896127_4897156_-|aspartate-semialdehyde-dehydrogenase
MRVGIVGATGQVGTVMRRILAERNFPVSELRLFASARSAGSAIEWQGSEVTVEDASTADYSGLDIVLFSAGGATSRALAEKVAAQGPVVIDNSSAWRRDPEVPLVVSEVNPHAIADRPKGIIANPNCTTMAAMPVLRPLHDEAGLEALVVATYQAVSGSGLAGVAELHGQAQKVVAEADQLTHDGAAVDFPEPGVYARPIAFNVLPLAGSVVDDGSFETDEEQKLRNESRKILEIPELKVSGTCVRVPVFSGHSLQINARFARPLGVERATELLKGAEGVELSEIPTPLQAAGQDPSYVGRIRVDETVENGLSLFVSNDNLRKGAALNAVQIAELVAAELKG
>NC_020990.1|WP_003948067.1|4897492_4900813_-|S8-family-serine-peptidase
MTSESPQAPISGARRAARVAVAAGLVAALCAGAPLPMAFAADEPATAPTVKSAADKLGSADAERLAEAKADGDKHVTMMIATQPGRTAEVAGKLKAVKGGSVGKTHDKLGYVRATVPTGQADAAIKAAAKLSAVHGIDLNQEIQLDDPTPSGDRAKGVKSAATDSDDFYGAPNAKTPAKNPFNPSFETGAVEFVEKNPKADGRGITIGILDSGIDLGHPALQKTTTGERKITDWVTATDPIVDGDQTWRPMVDAVSGPSFTYKGRTYKAPAGSYQVSVFAEAASKGGDADGDLNRDGDTTDTWGVLYDAKNGTVRVDLNDNGDFTDDEVLRPYKDKFQVGYFGKDDPKTDVVEQIPFVVELRKGVPMDPYGGSWVGKKADFVNIGIIEGSHGTHVAGITAANSLFGGKMNGAAPGAKLVSSRACTWSGGCTSVALTEGMIDLAANRGVDIINMSIGGLPALNDGNNARAELYTRIIDAFGVQLVISAGNSGPGANTIGDPSLADKVISVGATISKETWLANYGSEVRKPYAMMPFSSRGPREDGGFTPTLSAPGAAINTTQTWFPGGPTLEAGYDLPAGYSMLQGTSMASPQAAGASALLLSKAKQQGIDLTPAKLRSALTSTATQIDGVQAYEQGAGLINIVDAWKQINKQDGDTHEYTVRAPVDTAIDELLKDPGHGTGVYDREGGLKVGKKRLYDITVTRTTGPKKAVSHKLALVNNHDETFKLVGGKKVDLKLNKPVTLTVSAKAATKGLHSAILTVDDPSTQGTDQQIMTTVVAADELAKPSFTVKKSGEVDRNETRSYFVEVPEGAKSLEVSLGGLFGKSQVRFISIHPYGVPVDSTSTPNCYNNYNNGNGCRPDLRSYADPAPGVWEIEVEARRTSPLLRNPYQLEVSLLGVAFDPAVQTVPEAKVGTPAPVEWKITNENAALEGKLKGGPLGSSLSKRPEIKNGEAQTSEITVGEGVERLDVAIGNVSDVAADLDLTLYDEQGNQVAQTADGDSEEALSVAKPKPGTYTVEVYAYSVPSGSTAYDYRDVYFSAALGEVKVDTAKTVKLATGASAKIAAEVLVAAPAPEGRKFFGQVQVLNAKGTAAGSGSVEIGKVTE

Crispr_ID: NC_020990_27

• CRISPR_ID: NC_020990_27
• CRISPR_location: 4913591-4913677
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_27

Consensus_repeat	Method
TAGCCCGGCCGGCGTTTGAGGCC	CRISPRCasFinder

spacers of NC_020990_27

>27.1|4913614|41|NC_020990|CRISPRCasFinder
AGTCTTTGACCGGCACGGTTGAAACGGAGCCCGGCTACCAC

CRISPR arrays and Neighbor proteins around NC_020990_27

CRISPR arrays

The CRISPR arrays of NC_020990_27

>merge|NC_020990|27|4913591-4913677|CRISPRCasFinder
TAGCCCGGCCGGCGTTTGAGGCCAGTCTTTGACCGGCACGGTTGAAACGGAGCCCGGCTACCACCAGCCCGGCCGGCGTTTGAGGCC

>NC_020990|27|22|4913591-4913677|CRISPRCasFinder
TAGCCCGGCCGGCGTTTGAGGCC	AGTCTTTGACCGGCACGGTTGAAACGGAGCCCGGCTACCAC
CAGCCCGGCCGGCGTTTGAGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003948063.1|4905848_4906493_+|DSBA-oxidoreductase	unknown	unknown	gnl|CDD|376526
NC_020990.1|WP_037629490.1|4906579_4908034_+|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|223154
NC_020990.1|WP_003948049.1|4923986_4925384_+|trigger-factor	unknown	unknown	gnl|CDD|234956
NC_020990.1|WP_003948054.1|4916892_4918122_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|234945
NC_020990.1|WP_037629487.1|4921170_4922373_-|acyltransferase-family-protein	unknown	unknown	gnl|CDD|226122
NC_020990.1|WP_003948060.1|4908990_4910439_-|amino-acid-permease	unknown	unknown	gnl|CDD|224038
NC_020990.1|WP_003948061.1|4908193_4908832_-|superoxide-dismutase	unknown	unknown	gnl|CDD|223678
NC_020990.1|WP_003948057.1|4913768_4915205_-|amino-acid-permease	unknown	unknown	gnl|CDD|273797
NC_020990.1|WP_003948052.1|4919635_4920838_-|transporter	unknown	unknown	gnl|CDD|223551
NC_020990.1|WP_008411883.1|4925682_4926300_+|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl|CDD|178955
NC_020990.1|WP_003948059.1|4910625_4912071_-|amino-acid-permease	unknown	unknown	gnl|CDD|224038
NC_020990.1|WP_015507891.1|4915577_4916069_+|ribose-5-phosphate-isomerase	unknown	unknown	gnl|CDD|235509
NC_020990.1|WP_003948050.1|4923146_4923341_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_008411875.1|4912397_4912991_+|biotin-transporter-BioY	unknown	unknown	gnl|CDD|376871
NC_020990.1|WP_015507892.1|4918281_4919400_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NC_020990.1|WP_003948067.1|4897492_4900813_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173796
NC_020990.1|WP_003948065.1|4902596_4903013_+|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|366659
NC_020990.1|WP_008411884.1|4926367_4927039_+|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl|CDD|237133
NC_020990.1|WP_008411866.1|4903098_4905684_-|aminopeptidase-N	unknown	unknown	gnl|CDD|274121
NC_020990.1|WP_003948066.1|4901254_4902451_+|serine-hydrolase	unknown	unknown	gnl|CDD|365903

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003948063.1|4905848_4906493_+|DSBA-oxidoreductase	gnl|CDD|376526	pfam01323, DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure pfam00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyze one step in prokaryotic polyaromatic hydrocarbon (PAH) catabolic pathways. This family also contains members with functions other than HCCA isomerisation, such as Kappa family GSTs, whose similarity to HCCA isomerases was not previously recognized. Some members have been annotated as dioxygenases, dehydrogenases, or putative glycerol-3-phosphate transfer proteins, but are most likely HCCA isomerase enzymes.	2.6397e-08
NC_020990.1|WP_037629490.1|4906579_4908034_+|aspartate-aminotransferase-family-protein	gnl|CDD|223154	COG0076, GadB, Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism].	2.69224e-81
NC_020990.1|WP_003948049.1|4923986_4925384_+|trigger-factor	gnl|CDD|234956	PRK01490, tig, trigger factor; Provisional.	7.22577e-154
NC_020990.1|WP_003948054.1|4916892_4918122_-|GNAT-family-N-acetyltransferase	gnl|CDD|234945	PRK01346, PRK01346, enhanced intracellular survival protein Eis.	1.40306e-160
NC_020990.1|WP_037629487.1|4921170_4922373_-|acyltransferase-family-protein	gnl|CDD|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	2.7902e-32
NC_020990.1|WP_003948060.1|4908990_4910439_-|amino-acid-permease	gnl|CDD|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	5.43745e-155
NC_020990.1|WP_003948061.1|4908193_4908832_-|superoxide-dismutase	gnl|CDD|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	5.17808e-80
NC_020990.1|WP_003948057.1|4913768_4915205_-|amino-acid-permease	gnl|CDD|273797	TIGR01773, GABA_permease, gamma-aminobutyrate permease. GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines].	0
NC_020990.1|WP_003948052.1|4919635_4920838_-|transporter	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.06807e-40
NC_020990.1|WP_008411883.1|4925682_4926300_+|ATP-dependent-Clp-protease-proteolytic-subunit	gnl|CDD|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	8.14405e-121
NC_020990.1|WP_003948059.1|4910625_4912071_-|amino-acid-permease	gnl|CDD|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	1.41221e-159
NC_020990.1|WP_015507891.1|4915577_4916069_+|ribose-5-phosphate-isomerase	gnl|CDD|235509	PRK05571, PRK05571, ribose-5-phosphate isomerase B; Provisional.	5.17155e-85
NC_020990.1|WP_008411875.1|4912397_4912991_+|biotin-transporter-BioY	gnl|CDD|376871	pfam02632, BioY, BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is a component of the BioMNY transport system involved in biotin uptake in prokaryotes.	1.45441e-30
NC_020990.1|WP_015507892.1|4918281_4919400_+|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	4.6734e-35
NC_020990.1|WP_003948067.1|4897492_4900813_-|S8-family-serine-peptidase	gnl|CDD|173796	cd04857, Peptidases_S8_Tripeptidyl_Aminopeptidase_II, Peptidase S8 family domain in Tripeptidyl aminopeptidases_II. Tripeptidyl aminopeptidases II are member of the peptidase S8 or Subtilase family. Subtilases, or subtilisin-like serine proteases, have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure (an example of convergent evolution). Tripeptidyl aminopeptidase II removes tripeptides from the free N terminus of oligopeptides as well as having endoproteolytic activity. Some tripeptidyl aminopeptidases have been shown to cleave tripeptides and small peptides, e.g. angiotensin II and glucagon, while others are believed to be involved in MHC I processing.	1.14446e-63
NC_020990.1|WP_003948065.1|4902596_4903013_+|peptidoglycan-binding-protein	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	5.33887e-10
NC_020990.1|WP_008411884.1|4926367_4927039_+|ATP-dependent-Clp-protease-proteolytic-subunit	gnl|CDD|237133	PRK12553, PRK12553, ATP-dependent Clp protease proteolytic subunit; Reviewed.	2.22318e-122
NC_020990.1|WP_008411866.1|4903098_4905684_-|aminopeptidase-N	gnl|CDD|274121	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type. This family is a subset of the members of the zinc metallopeptidase family M1 (pfam01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site).	0
NC_020990.1|WP_003948066.1|4901254_4902451_+|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.26295e-58

Protein sequences

>NC_020990.1|WP_008411875.1|4912397_4912991_+|biotin-transporter-BioY
MSTAAASTRPGQVLADLLPASTVPRARLRDAALVTGGAALTGLAAQIVLPVPGSPVPVTGQTFAALLVGTALGAGRGFASLALYALVGMAGVPWFAEGTSGASMPSFGYVLGMLLAATVVGALARRGADRSVLRTAGLMVLGSALIYAVGVPYLALSTGMSLTSAVAAGLVPFLIGDALKAALAMGTLPLAWRLTRD
>NC_020990.1|WP_003948059.1|4910625_4912071_-|amino-acid-permease
MHDAPAGPGDPGATSATTARDPFDSAEPLGHGLKQRHLTMLGLGGVIGAGLFVGSGAGIAVAGPGIVVSYLIAGTLAMLVMRMLGEMSAAMPSSGSFSVHAERALGRWAGFSVGWLYWFLLVVVLAVEATGAAQIANGWVPSVPQWAWVLVFMLVFTGANLAAVKHFGEFEFWFAALKVGAIVLFLVLGVLAILGLLPETEPVGLAHLSGDGGFLPNGWSGVISGVLAVVFAFGGLEVVTIAAAESDDPARSVARAVRSAVYRILFFYVGSMLVIVTLLPWTAMRPGLSPYVAVLDGIGIPSAGQIMNIVVFVALLSALNANLYGSSRMVFSLAERGEAPRALLKVAPGGVPRRAVLASVAFGFVSVLLNLKWPDSVFLYMLNAVGAVLLFVWALIAVSQLRLRRLIEREAPERLVLRMWGYPWLTWAALVAMAVVFTLMLFDSTARPQLLWSSGAAALVLLVAGVREWRLRRGTGAAAAG
>NC_020990.1|WP_003948060.1|4908990_4910439_-|amino-acid-permease
MTRTTLTPGDTPGADQRPGGDQASDTGSALSNGLKQRHLSMIALGGVIGAGLFVGSGAGIAAAGPSIVFAYAASGLLVMLVMRMLGEMSAANPASGSFSVHAERAIGPWAGFTSGWAFWFLLCVAVGLEGIGAAEIMSGWLPGTPEWAWVALFMVIFCGTNLAAVKNFGEFEFWFATLKVVAIIVFLVIGVLAILGVLPGSEAPGTSNLTGEGGFLPNGSEGFIIGLLASVFAYGGLETVTIAAAESERPAEGVAKAVRTAMWRIGVFYVGSMAVIVTLVPWDDPAVAEKGPYVATLDHLGIPGSGQIMNVVVLIALLSAMNANIYGASRMACSLVARGQGPRKLGRVFNGVPRIAVLASSFFGFVCVLLSYWRPDDVFAWLLNMIGAVILVVWFFTAASQLLLRRRTEREAPERLVVRMWLFPGLTWVALAAMAGVFVLMAKEPDTRVQLLSTGSLTVALALAGYLLQRKRAAAPAGVGKG
>NC_020990.1|WP_003948061.1|4908193_4908832_-|superoxide-dismutase
MSVYTLPELPYDYAALEPVINPAIIELHHDKHHAAYVKGANDTLEQLAEARDKDQWGAVTGLEKSLAFNLSGHILHSIYWHNMTGDGGGEPLAEDGVGELADAIRESFGSFAGFKAQLTKAAATTQGSGWGVLAYEPLSGRLIVEQIYDHQGNVGQGSTPILVFDAWEHAFYLQYKNQKVDFIEAMWRVVNWQDVARRYASAKARENVLLAP
>NC_020990.1|WP_037629490.1|4906579_4908034_+|aspartate-aminotransferase-family-protein
MPKPEPPARPDVLKEIAALREADAPTRGGRTFAYVYDPAVEGLDALAADAYRAFADVNALDMTVFPSVARLENDLVARVAAHLGAPGCQGTFTSGGTESILLAVKTARDHARATRGVRAGELVLPATAHAAFHKAAHYLGLTSVTVPVDPETYRADPAATARALTPDTVLVVASAPSYAHGVLDPVAEIAALAAEAGVLCHVDACVGGWLLPFLRRAGREVPDFGLTVPGVTSLSVDLHKYGYADKGASVVLYRDAALRRHQYFAHADWPGYPVVNPTVQGTKSAGLLAQAWAVLRYLTDEEYTALAARVADAETRLLTGLAALDGLRVLGTPAAGLVAVTATGPDGTPDLSTVLHLADEMRARGWYLQPQLAHGALPPNLHLTLTPATADRVDALLADLTTALATARTLPPATPAPDLAALAATLDPVTLTDEEAAAVLTYAGLGPDTGTPDRMAPVLALLAALPTRLKERLLTEYIGSLFQI
>NC_020990.1|WP_003948063.1|4905848_4906493_+|DSBA-oxidoreductase
MTDPQQNTEVTADFWFDPLCPWAWMTSRWMLEVEKVRPVRVRWNVMSLAVLNEDRLDELPEGYRELLTQAWGPVRVVIAAQQLHGAEVAGPLYTALGTRYHNQQQPKDRATLVAALEEVGLPADLADYADKDTYDAELRASHAAGITKVGQDVGTPVIAVPGADGEEVAFFGPVVTPAPKGDQAAALWDGTLLVASVPGFYELKRTRTAEPSFD
>NC_020990.1|WP_008411866.1|4903098_4905684_-|aminopeptidase-N
MPGENLTRDEARERAALVAVESYDVALDLRSALGEVTGDGPRTFRSVTTIRFAGLRPGAATFVDLIAPSVSAVTLNGRALDVAEVFDGTRIALEGLEAENTLVVDAQCAYSRTGEGMHRFVDPQDGEVYLYTQYEPADSRRVYANFEQPDLKGRYRFSVTAPEGWGVWSNGAGERDADGVWRFAETEPISTYITCVVAGPYHYVTDDYRRTLPDGSELRIPLGAMCRKGLAPHFDADDIFLVTKQGLDFFHDHFGYPYPFGKYDQAFVPEYNLGAMENPGMVTFREEYIYRGKVTAASYERRATTILHEMAHMWFGDLVTMKWWDDLWLKESFADFMGSFALVEATRFTNGWTTFANNRKAWAYRADQLPSTHPITADIRDLQDAKLNFDGITYAKGASVLKQLVAYVGRDAFLEGARRYFQRHAFGNTTLADLLAVLEETSGRDLAGWSKAWLQTAGVNALTPELTLDAENRITELAVAQEAAASPLELRPHRVAVGLYRLDGVEGALVRYARAELDVTGPRTVVTELAGAEAPDLVLVNDDDLTYCKVRFDENSLATLRSRLGDIADPLARALCWSALWNMTRDGLMPARNFLSLVLEHAGRESDIGVLQMLHAWARTALVHYVVPARRDEAGRALAQGALAELRAAEPGGPAQLTWARFFASVASDEADLQLLGALLDGPARIDGLDMDQELRWTFLEPLATYGVVDEERIAAELARDDTASGKRHQVRCLAARPSEAVKAQAWVQVVESDALSNALVEATIAGFAQPSQRELTAPYAAKYFEAIGRVWEERSIQIGVLVVRGLFPSLQDGPEPLAAADAWLGEHTDAPPALRRLVLESRDDLARAHRAQVTDAGTGA
>NC_020990.1|WP_003948065.1|4902596_4903013_+|peptidoglycan-binding-protein
MGDPVTHRRRAFALLTASAALLAGAVTAAPAATAAPTAAAPKKCYTQSTIGLTCHHHYGAKWAEYGSTGAHVKEIQALINGTTTYYGTHGKALAVDGIYGAGTRSAVRWFQQKYIGASAVDGIVGPRTWDALRGFGRK
>NC_020990.1|WP_003948066.1|4901254_4902451_+|serine-hydrolase
MAAPTTPPRPARRHRRPARLAAALATATALATLTPAPLAAASTTRGHEGTQRVLDTAVADGVPGALARARDRHGVWNGTAGTADLDTGRARGADDRFRIGSVTKTFVATVLLQLQGERRIDLDDTVDQHLPGLVDGHGHDGTAITLRQLLNHTSGISNYTADPEFRRRAFGEEFLDHRYDTWKPGQLVAVAMRHAPDFAPGTSWNYSNTNYILAGMVIEKVTGHGWEKEVERRILRPLGLRATSAPRTDPHLPRPAGRAYSFLGDPDREHPYDVTELNPSQAGAAGAMISTTADLDRFQRALLGGRLLPPAQLRQMTTTVEVHPSAPHVRYGLGLMRQTLSCGIRIWGHDGGIHGSATLAFTTRDTRHSYQANLNGEWSPSDPADAVALTEAEFCREG
>NC_020990.1|WP_003948067.1|4897492_4900813_-|S8-family-serine-peptidase
MTSESPQAPISGARRAARVAVAAGLVAALCAGAPLPMAFAADEPATAPTVKSAADKLGSADAERLAEAKADGDKHVTMMIATQPGRTAEVAGKLKAVKGGSVGKTHDKLGYVRATVPTGQADAAIKAAAKLSAVHGIDLNQEIQLDDPTPSGDRAKGVKSAATDSDDFYGAPNAKTPAKNPFNPSFETGAVEFVEKNPKADGRGITIGILDSGIDLGHPALQKTTTGERKITDWVTATDPIVDGDQTWRPMVDAVSGPSFTYKGRTYKAPAGSYQVSVFAEAASKGGDADGDLNRDGDTTDTWGVLYDAKNGTVRVDLNDNGDFTDDEVLRPYKDKFQVGYFGKDDPKTDVVEQIPFVVELRKGVPMDPYGGSWVGKKADFVNIGIIEGSHGTHVAGITAANSLFGGKMNGAAPGAKLVSSRACTWSGGCTSVALTEGMIDLAANRGVDIINMSIGGLPALNDGNNARAELYTRIIDAFGVQLVISAGNSGPGANTIGDPSLADKVISVGATISKETWLANYGSEVRKPYAMMPFSSRGPREDGGFTPTLSAPGAAINTTQTWFPGGPTLEAGYDLPAGYSMLQGTSMASPQAAGASALLLSKAKQQGIDLTPAKLRSALTSTATQIDGVQAYEQGAGLINIVDAWKQINKQDGDTHEYTVRAPVDTAIDELLKDPGHGTGVYDREGGLKVGKKRLYDITVTRTTGPKKAVSHKLALVNNHDETFKLVGGKKVDLKLNKPVTLTVSAKAATKGLHSAILTVDDPSTQGTDQQIMTTVVAADELAKPSFTVKKSGEVDRNETRSYFVEVPEGAKSLEVSLGGLFGKSQVRFISIHPYGVPVDSTSTPNCYNNYNNGNGCRPDLRSYADPAPGVWEIEVEARRTSPLLRNPYQLEVSLLGVAFDPAVQTVPEAKVGTPAPVEWKITNENAALEGKLKGGPLGSSLSKRPEIKNGEAQTSEITVGEGVERLDVAIGNVSDVAADLDLTLYDEQGNQVAQTADGDSEEALSVAKPKPGTYTVEVYAYSVPSGSTAYDYRDVYFSAALGEVKVDTAKTVKLATGASAKIAAEVLVAAPAPEGRKFFGQVQVLNAKGTAAGSGSVEIGKVTE
>NC_020990.1|WP_003948057.1|4913768_4915205_-|amino-acid-permease
MTSQPPLAKVEQAPDGPAGPTPAEGQGSDGLQAGLKNRHLSMIAIGGVIGAGLFVGSSAGIAAAGPAILVSYAIVGLMVVLVMRMLGEMAAARPSSGSFSAYADMALGRWAGFSIGWLYWFFWVVVLAVEATAGAVILNGWIPAVPQWGWALIVMVVLTGTNLASVASYGEFEFWFAGIKVVAIAAFVLIGVLAVFGVLPGSDNPGAGFANLTAHGGFLPNGAGSILTGVLMVVFSFMGSEIVTLAAGESANPQRAVRKATNSVIWRIAVFYLGSIFVVVALLPWDSKSIVEDGSYVAALNSIGIPHAGQIMNVIVLTAVLSCLNSGLYTASRMAFSLGKRGDAPAAFARVNARGVPQAAILGSVVFGFAAVWFNYQWPETVFQFLLNSSGAVALFVWLVICFSQLRLRGVIARETPEKLVVRMWLFPYLTWVTIAGIVFVIGYMLFDEAGRTQMALSLLVAVLVVAVSLVKHRGARV
>NC_020990.1|WP_015507891.1|4915577_4916069_+|ribose-5-phosphate-isomerase
MRVYLGSDHAGYELKNHLVDWLKANGHDPVDCGPHVYDAADDYPPFCLRAAERTAADPDSLGIVIGGSGNGEQIAANKVKGVRCALAWSKETAALGREHNNANVVSVGARMHTEEEATDFVATFLATPYSDEARHTRRIDMLSAYETTGELPPIPAHHPQHDA
>NC_020990.1|WP_003948054.1|4916892_4918122_-|GNAT-family-N-acetyltransferase
MTSGAEVLRAEDWDQWYSTLELAFGGVPEAPEERELYQRLTEPERSLVVWDGSEVVGTAGAFTFRVTVPGGRPVAAAGVTMVGVAPTHRRRGILTAMMRRQLDDVRARGEALAMLTASEPGIYGRFGYGIATLKLSAEIDTAQVRLTVPEGTDEVVLRRADPREALKVCEEVYARQVAGRPGMLVRAPGWEEQGLLDPPGNRAGGSPLQCVLAERDGEVVGYTRYRTHPSWGLGGPDGAVTVQDLEASGPAVHAALLRYLCGIDLMRTVKLPSRPVDDAWQYLVSDARRCVPRLGDVLQVRLVEVGAALQQRSYQAPLDVVLEVTDAFCPWNEGRWRLSADAEGAACERTEAEPDLALSVRELGAAYLGGVPLSGLAAAGRVRELRPGALARTSTAFGSDVAPWLPHGF
>NC_020990.1|WP_015507892.1|4918281_4919400_+|serine/threonine-protein-phosphatase
MRKRWHRARTGLRKSAVDYFRGDGSDWVAFAGLFLTVPAIAVGTIVGPEWCDPAALVLPVIAGGLVLRPATLLLLYASATAALVVESLVLGSGPTSQVPVGVTPGTVLTVAAAGLFGLVIAQFRSRVGVPWRRGGTMLFDLRERIRVQSRLPHLPSGWHHEMALRPAGGQSFSGDFVVAARTHGGRTLEVVLTDVSGKGMDAGSRALLLSGAFGGLLGSLPPHAFLPAANGYLLRQDWDEGFATSIHLVLDLDSGDYELFSAGHLPAVQLHSGTGQWEEKAAEGPLLGVYDGCQFDPVKGSLAPGDVLMLYTDGLVEAAGRDLSEGIDRLTGEADRYVPGGFEGAAWHLIEAVAKDVNDDRALLLLSRKPTT
>NC_020990.1|WP_003948052.1|4919635_4920838_-|transporter
MGGAFVAAAVLARLGGRIGLPTIPLFILAGILLGPHTPGVVLVSDPHDLEMLSALGLVLLLFYLGLEFHIDDLKAGGRNMALAGGIYLALNVGAGLGFGFALGWGVSEALVLAGVLGFSSSAIVTKILVDTRRLGNPETKPILGIIVVEDVFIALYLAALQPILSGADSLSTALVDGGKAFGFLIALALVARYGTRVVGRLINTPDDEILTISFLGAAVLMAGVSEWFGVADAIGAFMVGLMLGSTTSGKRILKLVHPLRDAFGAIFFFVFGLSINPGDLPGVVWPVLIAVALTLSMNVISGITAARIYRFGAQPAANIATTLLARGEFALILATMAAAAGLDARLSPFIAGYVLLLAIMAPLAAKQSNWLARILPGGTSGGDGGDAGASGASVPERVSV
>NC_020990.1|WP_037629487.1|4921170_4922373_-|acyltransferase-family-protein
MTNSLRPHGHHSQPLPPVQEPADGMTAPRPSPTSQERPPGPERPPAAAAKPAKSRDPFFDNAKYLAIVLVAMGHAWQPLTSDSRAAEALYMVVYAFHMPAFIVISGYFSRSFDMRKDRLQRLVTGVAVPYILFETAYSLFKRWADDDPTHPISLLDPWYLTWFLIALFIWRLTTPLWKIVRWPVPLALALALLASVSPDVGDDLDLQRVLQFLPFFVVGLVLKPEHFQMVRRREVRLLALPVFAAALLVGYWAAPRMSSAWFYHRDSAQEMGFAWWVGVIMTLALFGCSMVLTACFFAWVPRRHMWFTALGAGTLYGYLLHGFLAKGSRFWGWYETYDWVRTPLGMIGVTLIAGAIVTVLCTPPVQRLFRFAMEPKMNWAFKRDATELARERAKSTAAIR
>NC_020990.1|WP_003948050.1|4923146_4923341_+|hypothetical-protein
MAISLSVVVLLAIVMVVLIRGGSLKAGPAVVAILFGFFLASSGMAPAIQRVLDSIAQTVSGISF
>NC_020990.1|WP_003948049.1|4923986_4925384_+|trigger-factor
MKSAVETLNPTRVRLTVEVPFEELKDSLDAAYKKINQQVTVKGFRKGKIPARVIDQRFGRGAVLEEAVNDALPKFYTEAVNEGELNVLGQPEVDITELKDGELLAFTAEVDIRPEIEIPDYSGIEVEVDPVEVTDEDVDKAVEELRERFASTAPVERPAEDGDVVTLDLEAKVDGEVLEDGLASDVSYTIGSGELLDGIDDAVKGLEAGGEATFTSELKGGSAAGKEAEITVKVSKVAKRELPELDDDFAQLASEFDTLEEVRADSRKRLENMKQYDQATQAQERVLDALLELAEVPIPEKLLEDEVNTRKHNLEHHQLGQMGLDLAKYLEIQGKTAEEFDAETREQAIKGIKTQFILDELVNKEKLNVDQEELTEHLMRRAASSGMSPDQFAQAVVEGGQVPMLVGEVARGKALAVVVEAVTVKDTNGEVVDLSDDEDEAAEATEAAAGQTEGDAAEAKADSDK
>NC_020990.1|WP_008411883.1|4925682_4926300_+|ATP-dependent-Clp-protease-proteolytic-subunit
MTNLMPSAAGDPSIGGGLGDQVYNRLLGERIIFLGQPVDDDIANKITAQLLLLASDPDKDINLYINSPGGSISAGMAIYDTMQFIKNDVVTIAMGLAASMGQFLLSAGTPGKRFALPNAEILIHQPSAGLAGSASDIKIHAERLLHTKKRMAELTAFHTGQSVEQITRDSDRDRWFSADEAKEYGLIDEVIASAANVPGGGGTGA
>NC_020990.1|WP_008411884.1|4926367_4927039_+|ATP-dependent-Clp-protease-proteolytic-subunit
MNNFPGSGALGADGEYAGPRAESRYIVPRFVERTSQGVREYDPYAKLFEERVIFLGVQIDDASANDVMAQLLCLESIDPDRDISIYINSPGGSFTALTAIYDTMQFVKPDIQTVCMGQAASAAAVLLAAGSPGKRMALPNARVLIHQPYSETGRGQVSDLEIAANEILRMRAQLEEMLAKHSTTPLDKIRDDIERDKILTAEDALAYGLIDQIVSTRKLNAGV

Crispr_ID: NC_020990_28

• CRISPR_ID: NC_020990_28
• CRISPR_location: 5118735-5118886
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_020990_28

Consensus_repeat	Method
CAGCCCGGCCGGCGCTTGAGGCC	CRISPRCasFinder

spacers of NC_020990_28

>28.1|5118758|42|NC_020990|CRISPRCasFinder
ATCTTGAACGGACGAGTCCGATCCGGACCTCGCCCCAAAACC
>28.2|5118823|41|NC_020990|CRISPRCasFinder
GTCCTGAACCGTCAGGTTCTCCCGGGCCCAAGCCCAAAGAT

CRISPR arrays and Neighbor proteins around NC_020990_28

CRISPR arrays

The CRISPR arrays of NC_020990_28

>merge|NC_020990|28|5118735-5118886|CRISPRCasFinder
CAGCCCGGCCGGCGCTTGAGGCCATCTTGAACGGACGAGTCCGATCCGGACCTCGCCCCAAAACCCAGCCCGGCCGGCGCTTGAGGCCGTCCTGAACCGTCAGGTTCTCCCGGGCCCAAGCCCAAAGATCAGCCCGGCCGACGCTGAGGCCA

>NC_020990|28|23|5118735-5118886|CRISPRCasFinder
CAGCCCGGCCGGCGCTTGAGGCC	ATCTTGAACGGACGAGTCCGATCCGGACCTCGCCCCAAAACC
CAGCCCGGCCGGCGCTTGAGGCC	GTCCTGAACCGTCAGGTTCTCCCGGGCCCAAGCCCAAAGAT
CAGCCCGGCCGACGCTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003947881.1|5115121_5116159_-|rod-shape-determining-protein	unknown	unknown	gnl|CDD|336482
NC_020990.1|WP_003947884.1|5112479_5112692_-|CDGSH-iron-sulfur-domain-containing-protein	unknown	unknown	gnl|CDD|378163
NC_020990.1|WP_003947878.1|5118050_5118650_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003947875.1|5120529_5120958_+|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl|CDD|274649
NC_020990.1|WP_010637672.1|5125185_5126085_-|hypothetical-protein	unknown	unknown	gnl|CDD|238870
NC_020990.1|WP_003947885.1|5111442_5112483_-|iron-containing-redox-enzyme-family-protein	unknown	unknown	gnl|CDD|379634
NC_020990.1|WP_003947870.1|5126577_5127072_+|DUF3145-domain-containing-protein	unknown	unknown	gnl|CDD|378644
NC_020990.1|WP_003947876.1|5119428_5120448_+|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|176190
NC_020990.1|WP_003947879.1|5117767_5117953_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003947872.1|5122661_5125145_+|glycoside-hydrolase-family-3-protein	unknown	unknown	gnl|CDD|224389
NC_020990.1|WP_015507939.1|5118917_5119340_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_020990.1|WP_003947883.1|5112705_5113380_-|methyltransferase	unknown	unknown	gnl|CDD|184931
NC_020990.1|WP_003947869.1|5127162_5128434_-|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	unknown	unknown	gnl|CDD|238430
NC_020990.1|WP_003947868.1|5128580_5128829_-|acyl-carrier-protein	unknown	unknown	gnl|CDD|179197
NC_020990.1|WP_015507940.1|5121026_5121857_+|EI24-domain-containing-protein	unknown	unknown	gnl|CDD|179898
NC_020990.1|WP_003947882.1|5113725_5114106_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_010637689.1|5116335_5117661_+|MFS-transporter	unknown	unknown	gnl|CDD|236700
NC_020990.1|WP_015507936.1|5114200_5114989_-|VOC-family-protein	unknown	unknown	gnl|CDD|319911
NC_020990.1|WP_003947886.1|5110518_5111403_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187613
NC_020990.1|WP_003947873.1|5121876_5122443_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003947881.1|5115121_5116159_-|rod-shape-determining-protein	gnl|CDD|336482	pfam06723, MreB_Mbl, MreB/Mbl protein. This family consists of bacterial MreB and Mbl proteins as well as two related archaeal sequences. MreB is known to be a rod shape-determining protein in bacteria and goes to make up the bacterial cytoskeleton. Genes coding for MreB/Mbl are only found in elongated bacteria, not in coccoid forms. It has been speculated that constituents of the eukaryotic cytoskeleton (tubulin, actin) may have evolved from prokaryotic precursor proteins closely related to today's bacterial proteins FtsZ and MreB/Mbl.	1.92602e-130
NC_020990.1|WP_003947884.1|5112479_5112692_-|CDGSH-iron-sulfur-domain-containing-protein	gnl|CDD|378163	pfam09360, zf-CDGSH, Iron-binding zinc finger CDGSH type. The CDGSH-type zinc finger domain binds iron rather than zinc as a redox-active pH-labile 2Fe-2S cluster. The conserved sequence C-X-C-X2-(S/T)-X3-P-X-C-D-G-(S/A/T)-H is a defining feature of this family. The domain is oriented towards the cytoplasm and is tethered to the mitochondrial membrane by a more N-terminal domain found in higher vertebrates, MitoNEET_N, pfam10660. The domain forms a uniquely folded homo-dimer and spans the outer mitochondrial membrane, orienting the iron-binding residues towards the cytoplasm.	1.18255e-15
NC_020990.1|WP_003947875.1|5120529_5120958_+|organic-hydroperoxide-resistance-protein	gnl|CDD|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	9.82691e-73
NC_020990.1|WP_003947885.1|5111442_5112483_-|iron-containing-redox-enzyme-family-protein	gnl|CDD|379634	pfam14518, Haem_oxygenas_2, Iron-containing redox enzyme. The CADD, Chlamydia protein associating with death domains, crystal structure reveals a dimer of seven-helical bundles. Each bundle contains a di-iron centre adjacent to an internal cavity that forms an active site similar to that of methane mono-oxygenase hydrolase.	2.91329e-51
NC_020990.1|WP_003947870.1|5126577_5127072_+|DUF3145-domain-containing-protein	gnl|CDD|378644	pfam11343, DUF3145, Protein of unknown function (DUF3145). This family of proteins with unknown function appear to be restricted to Actinobacteria.	1.83132e-97
NC_020990.1|WP_003947876.1|5119428_5120448_+|NADP-dependent-oxidoreductase	gnl|CDD|176190	cd05288, PGDH, Prostaglandin dehydrogenases. Prostaglandins and related eicosanoids are metabolized by the oxidation of the 15(S)-hydroxyl group of the NAD+-dependent (type I 15-PGDH) 15-prostaglandin dehydrogenase (15-PGDH) followed by reduction by NADPH/NADH-dependent (type II 15-PGDH) delta-13 15-prostaglandin reductase (13-PGR) to 15-keto-13,14,-dihydroprostaglandins. 13-PGR is a bifunctional enzyme, since it also has leukotriene B(4) 12-hydroxydehydrogenase activity. These 15-PGDH and related enzymes are members of the medium chain dehydrogenase/reductase family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES.	0
NC_020990.1|WP_003947872.1|5122661_5125145_+|glycoside-hydrolase-family-3-protein	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	4.85154e-63
NC_020990.1|WP_015507939.1|5118917_5119340_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.20978e-15
NC_020990.1|WP_003947883.1|5112705_5113380_-|methyltransferase	gnl|CDD|184931	PRK14967, PRK14967, putative methyltransferase; Provisional.	1.94292e-83
NC_020990.1|WP_003947869.1|5127162_5128434_-|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	gnl|CDD|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	0
NC_020990.1|WP_003947868.1|5128580_5128829_-|acyl-carrier-protein	gnl|CDD|179197	PRK00982, acpP, acyl carrier protein; Provisional.	2.40477e-27
NC_020990.1|WP_010637672.1|5125185_5126085_-|hypothetical-protein	gnl|CDD|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	1.36119e-23
NC_020990.1|WP_015507940.1|5121026_5121857_+|EI24-domain-containing-protein	gnl|CDD|179898	PRK04949, PRK04949, putative sulfate transport protein CysZ; Validated.	8.35944e-22
NC_020990.1|WP_010637689.1|5116335_5117661_+|MFS-transporter	gnl|CDD|236700	PRK10489, PRK10489, enterobactin transporter EntS.	1.21394e-72
NC_020990.1|WP_015507936.1|5114200_5114989_-|VOC-family-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	7.14806e-28
NC_020990.1|WP_003947886.1|5110518_5111403_-|SDR-family-oxidoreductase	gnl|CDD|187613	cd05355, SDR_c1, classical (c) SDR, subgroup 1. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.31712e-149
NC_020990.1|WP_003947873.1|5121876_5122443_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	5.38686e-12

Protein sequences

>NC_020990.1|WP_003947878.1|5118050_5118650_-|hypothetical-protein
MCAAVGGTSSFGSLEFQLVLLRRMADFQAGMVEEARRELGVDAGAMREANRRWQAMVRSPRGRRGAGLLRSVLGVPEAVERRVVGDLECEALRWPVVLWPALRFEAVVAPGGALWNEWLVQGPGDAPPAPAALDALRPWEYTVEEVARAFPARPMQGSAPTRWRLRVTAPEYEGGPVRDAVAEFTWGLLQEVTVVEGRE
>NC_020990.1|WP_003947879.1|5117767_5117953_-|hypothetical-protein
MRSATDGVHTVTATGPKSLSQGPCSKSRAPCPRAHSTKEIPPMNLLTDILAGLVHFVGRLV
>NC_020990.1|WP_010637689.1|5116335_5117661_+|MFS-transporter
MHSETSKDEPPAPDDAQAILPSPRDPVAAPPRKRLLADLTPLRTSADFRRLWIGNTISWVGQGMTALAISLQVYDLTRSSFSVGLVGLFSLVPLVVFGLYGGAIADTVDRRLLGLASSTGSWLLAVALAVAAFAGFHQVWFLYAVVALQAVCAALNSPARTSMIPRLLPAEQLPAANALNSMTTTFGTMTGPMLGGALVGLWGYQAAYLIDAVAFTAALYAMWRLPAMRPQREEGSRGRASVLDGLRFLATRPNIRMTFFTDLCAMVLAHPRALFPAVAVVWYGGDAKTAGLLVAAPAVGALLGSVFSGWLGRVHRHGVAILLAVGGWGLAVAVFGLTRNLWLGLLFLALAGAADAISMVFRSTMLQAATPDAMRGRLQGVFIVVVAGGPRLGDFLAGSVGDLASPTVAVTGGGLLCVLAVTALGLRWRNFARYDARDPQP
>NC_020990.1|WP_003947881.1|5115121_5116159_-|rod-shape-determining-protein
MTASLEQLRRCHFAVDLGAARTRVFIKGEGVVVDEPSAAAINTRTGALIAVGTLAEQMTGRTPGYIRVVRPVKGGTVIDIDMAQRMLRHLLGDKVRRALRRKPRLRAAACTPHDADPLAQRATVETLVGIGARRVELVDTLIAAAVGCGLPVERPEASMILVCGAATTQIAVLSLGSIVTAERVPVGGNAIDHSVLSYLRHHHELMLPSQSVRPLHVALRGGDLSMTGSGTTEIHGRDVATGLARSVEVDTVGLRSAISIPLTGVLDGIGKVLRDCPPDLVADLADRGIMMVGGSALMPGLDQMIREATGMPVQVAERPDIASVTGLGAMLDGQIEPMTLNPLSA
>NC_020990.1|WP_015507936.1|5114200_5114989_-|VOC-family-protein
MSPFPDGAPCWADAMFPDVAAARDFYGQVLGWTFDDLGEEYGNYTMALVDGKPVAALMPVMPGPDAPALWNLYLATSDAAAVTGRVEGLGGTVAMGPEDVGGFGITSSLRDPAGTAFSLWQPNTHPGFGLTEVPGAYAWAEVYTRDAAATDRFFPELFGYQVGVMEDPEMDFRIWSVAGRPVLGRMAMTDDFPPEVPSYVNVYFSVPDCDAALDTAVRLGGQVHYGPTTTPFGRFAAVSDQQGASFSVIDTGTTEGEMPPMT
>NC_020990.1|WP_003947882.1|5113725_5114106_+|hypothetical-protein
MYATTEAQVLGASESGGIGWVLGIGLAVLAVAVVGMLVWVVRKGIQTRAEEPEPPSPESQPHKPARPTHEEDYREDDVGEFPTDGGRLLPHELKGVSSHQAEPPEGGRPKHTPGHSGGFGSGGAGG
>NC_020990.1|WP_003947883.1|5112705_5113380_-|methyltransferase
MTSAPAPPLSPVLAPAGVYAPQHDTALLTRAVTAEQPGPGTEVLDLGTGTGAVALHAARTGARVTAVDISWTAVLTARLNAARARCRLRVHRGDLTAPVTGRTFDLVVSNPPYVPAPEETPPASGPARAWDAGPDGRALLDRICADAPAALRPGGTLLLVHSALCGTEATLSRLAAAGMRAEVSDRVRIPYGPVLTGRHEWLVARGLADGSPWEELVIVRAVHA
>NC_020990.1|WP_003947884.1|5112479_5112692_-|CDGSH-iron-sulfur-domain-containing-protein
MRLDPDGGPLLVDGPVEVVTEDGTTHFSHRPTVALCTCRRSARYPWCDTSHRARAPERADAPDSPEEEPR
>NC_020990.1|WP_003947885.1|5111442_5112483_-|iron-containing-redox-enzyme-family-protein
MTTPARSRLTRPRLPEPRGPVSAGVVEALRSGGSPVTDGAEATADPYGEDLQLALYVLYELHYQGFAGAPADDSREWDPELLALRATLEQPFLAALRADAERPASAAAALDALLVEPAGHRPGSVSHHLRRTHRLPELREYAALRSLYHLKEADPHAWMIPRLRGRAKAGLAAVEYDEFGAGRAEDVHARLYAELMAELGLEPAYGHYLDAAPAAALATVNLMSLFGLHRALRGALVGHFAAVEVTSSPGSRRLADALRKAGAGPAAVRFYEEHVEADAVHEQVVRRDVVAGLLADEPELDADVAFGVAATSLLEDRLGALLLDAWTQDRSALLPGHHADAVARPA
>NC_020990.1|WP_003947886.1|5110518_5111403_-|SDR-family-oxidoreductase
MTDPRGHQDAAGDRPRPPQPEQSQEHPGSTARMDPVPDHGEESYRGRGLLRDRRALLTGGDSGIGRAVALAFAREGADLVFAHLPEERDEARVTLRLITEAGRTGIAVPCDIRDEETCRELVARTVAELGGLDLLVNNAAYQMSQPEGIEAITTEQFDRVMRTNLYAMFWLCREARPHLGPGSAIINTTSVQGFQPSPHLLDYAMTKGAITTFTHGLAQMLAADGIRVNAVAPGPVWTPLIPSTLPSTEEFGAQSPLGRAAQPAELAPAYVFLASDQASYITGEIMNVTGGQPL
>NC_020990.1|WP_015507939.1|5118917_5119340_-|MarR-family-transcriptional-regulator
MATRTDPLTLEVVELIGAVVARYHEEYDRAAAEQALTGAQARVLGLLSLEAMPMRQIARRLKCEPSNVTGIVDRLALRGLVERQADPGDRRIKVAALTAEGREVARVLRDSLDFAREPLAGFSREEREVLRGMLRRMAGE
>NC_020990.1|WP_003947876.1|5119428_5120448_+|NADP-dependent-oxidoreductase
MTALPSSGREWHLVARPDGWPTPEDFALREVPVEAPTAGRILVRNLYFSVDPYMRGRMNDVKSYVPPFQLDAPMDGGAVGEVIASEAEGFAVGDHVLHGLGWREYANLPAKHAKKVDGSLAPLSAYLGVLGMPGLTAYAGLLDVASFKPGDAVFVSGAAGAVGSEVGQIARLKGASRVIGSAGSDEKVKLLVDEYGFDAAFNYKNGPVAEQLKEAAPDGIDVYFDNVGGDHLEAALGRLNQFGRVALCGAIAQYNDKGAPTGPRNLALAIGKRLRLQGFIVGDHSDLQPQFVDEVSGWVRSGELKYNETFVEGIDNGVEGFLGMLRGENTGKMIIDLSR
>NC_020990.1|WP_003947875.1|5120529_5120958_+|organic-hydroperoxide-resistance-protein
MSIQHIDVAYTAVATAENGRDGRVATDDGKLDVVVNPPKEMGGSGAGTNPEQLFAAGYSACFQGALGVVARAAKADIKGSTVTAQVGIGKAEAGGFGLEVELITSIPNVDRATAEELVAKAHEVCPYSNATRGNIKVTLTVA
>NC_020990.1|WP_015507940.1|5121026_5121857_+|EI24-domain-containing-protein
MGDLGVGFRYLMNGQRWALSHGKTFGLGLLPGLITLVVYAAALVALAFGADDLIAWATPFADGWGSPWLGLFRGFLTAVLFALGLMLAVITFTSVTLLVGSPFYDAVSERVDASIDGNVPTSGRSFGYDLWVSTRDSLRILVRAAIWGVLLFALGFIPVVGQTAIPVAGFFVTGFFLTEELASVALARRDVDLRGRLTLLRSRRMLAWGFGVPLALAYVIPFVAVFLMPGAVAGATLLSRDLLGEPTAPTADAVPGTGEAAPAGLAKPPADTPAER
>NC_020990.1|WP_003947873.1|5121876_5122443_-|TetR/AcrR-family-transcriptional-regulator
MSRGGRNEDRRGEILRAALEVISERGYRAASLAAVAERVGLTQQGLLHHFPTKEALLVGVLEARDQWDATPRESWRLDLLAALVDYNATRPAIVRTFSALLGESVTGDHPARAYFTGRYAVVRADMAAILRTAYGERLPSGLTPEQAAPLLVAVMDGLQYQWLLDPEAVDMTAAFRDFLVLLGEEPPS
>NC_020990.1|WP_003947872.1|5122661_5125145_+|glycoside-hydrolase-family-3-protein
MTDHPGKEYEDRLDEAVEAAFAALDLDAKSRLLAGQDMWSLPALPEAGVGSLVMSDGPVGVRGVRWTAADPSVALPSPTALAASWDPELARRAGVLLAQEARRKGVHVLLAPTVNLHRSPLGGRHFEAYSEDPYLTGAIGTGYVQGVQSGGVGTTVKHFAGNDAETERFTVDNRIDARTLREVYLAPFETITTEARPWGVMTAYNSVNGTTMTEHHELVTGVLRGEWGFDGINVSDWLAARSTGPALTAGLDLAMPGPRTVHGPALAAAVRAGQVDEAYVDAAVRRVLRLAGRVGILDGVGPAVGPGQLPAEADGAAVAREVARRGFVLLRNAPTADGTPVLPLGPEPGTVALIGAAAREARALGGGSATVFPPHLTSPLEGLRAALGEEAVTFRVGADPQTDLGPATQGFDLRAVCRDAEGTVLGTAPVPGGAVQWVGSDLPEGVTHDTLHSIEITGTYTPPESGRHTFGTRGLGAFRLTVDGRELWSGSQGLGEARDPFEAFFGAPTERATAHLTAGTPVDLSLEYVRTRLPDAPLEGVSVSLVHLLPQRDPDELIAEAAEAARQAETAVVVVATTEAVESEGFDRTSLALPGRQDDLVRAVVAANPRTVVVVNAGSPVEMAWREEAAAVLLTWFPGQEGGSALADVLLGHEEPGGRLPTTWPARLADAPVTDTAPTDGRLDYTEGVFVGYAAWERAGTTPAYPFGHGLGYTDWAYETLRAEGRTVTVGLRNTGTRPGRETVQLYLAPPPAAPGEPERPAQRLAGFALAEAGPGESTEVTVELPGRAFQIWDEAAGGWSHRPGRYEVRAARSAADPRLTLALQED
>NC_020990.1|WP_010637672.1|5125185_5126085_-|hypothetical-protein
MGERGVRGRRRRAGTAAALAVLLGAVLPACGSAPSSSQGSDEQAAPRARQQTGWDTRPASLAAVGDSITRGFDACSVLADCPEASWATGSDPGVRSLALRLLGERGAAERSWNHAVSGARAADLPAQVERAVQDRPELLTVMVGANDACRTSTRHMTKVKDFRKSVEEAMEIVREELPRTQVYMASVPDLKRLWSEGRTSELGKQVWALGICRSMLSKPDAVDKKSVKRRAKVHKRVKAYNRVLAEVCGQDRLCRTDGGAVFDFRFTGTQLSPWDWFHPSKNGQAHIARIAYRAVTAKG
>NC_020990.1|WP_003947870.1|5126577_5127072_+|DUF3145-domain-containing-protein
MTTRGVLYVHSAPRALCPHVEWAVAGVLGVRVSLDWIRQPAAPGTWRAEFSWQGQAGIASRLASALRGWQQLRFEVTAEPSPGAEGERYSSTPGLGIFHAVTGIHGDILVPEDRLRAALVRSQAGETDLEAEIARLLGKPWDDELEPFRHAGEGAPVRWLHQVV
>NC_020990.1|WP_003947869.1|5127162_5128434_-|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein
MSPTNRTVVVTGIGATTPLGGDAASTWEGLIAGRSGVRPLDDERYADLPVRIAAQIAVEPAEVLPRPLVRKLDRSAQFALIAAREAWADAGYTAMAGEDEQISPERLGTVIASGIGGVTTLLDQYDVLKEKGARRVSPHTVPMLMPNSPSANVGLEVNARAGVHTPVSACASGAEAIGYAVEMIRTGRADVVVAGGTEAAIHPLPVVAFANMMAMSKNNDEPEKASRPYDTGRDGFVLGEGAGVVVLESAEHAAARGASVYCEVLGQGLSADSHHIAQPEPTGRGIAAALQHLMDDTDLKPSEVVHLNAHATSTPQGDIAEVKALRQILGEDLEHVAISATKSMTGHLLGGAGGIETVATVLALKHRKAPPTLNVDELDPAITEAGADVVRGEARELPEGTVAAINNSFGFGGHNVVLAFRTV
>NC_020990.1|WP_003947868.1|5128580_5128829_-|acyl-carrier-protein
MAATQEEIVDGLAEIVNEIAGIPVEDVQLDKSFTDDLDVDSLSMVEVVVAAEERFDVKIPDEDVKNLKTVGDATSYILKHQG

Crispr_ID: NC_020990_29

• CRISPR_ID: NC_020990_29
• CRISPR_location: 5317814-5317900
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_29

Consensus_repeat	Method
AGCCCGGCCGGCGTTTGAGGCCA	CRISPRCasFinder

spacers of NC_020990_29

>29.1|5317837|41|NC_020990|CRISPRCasFinder
GTCTTTGACCGGCACGGTCGGGACGGAGCCCGGCACACAAC

CRISPR arrays and Neighbor proteins around NC_020990_29

CRISPR arrays

The CRISPR arrays of NC_020990_29

>merge|NC_020990|29|5317814-5317900|CRISPRCasFinder
AGCCCGGCCGGCGTTTGAGGCCAGTCTTTGACCGGCACGGTCGGGACGGAGCCCGGCACACAACAGCCCGGCCGGCGATTGAGGCCA

>NC_020990|29|24|5317814-5317900|CRISPRCasFinder
AGCCCGGCCGGCGTTTGAGGCCA	GTCTTTGACCGGCACGGTCGGGACGGAGCCCGGCACACAAC
AGCCCGGCCGGCGATTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_015508000.1|5313997_5314675_-|DoxX-family-membrane-protein	unknown	unknown	gnl|CDD|311556
NC_020990.1|WP_015508002.1|5320258_5320921_+|dihydroxyacetone-kinase-subunit-L	unknown	unknown	gnl|CDD|237723
NC_020990.1|WP_003947707.1|5308733_5309360_+|precorrin-8X-methylmutase	unknown	unknown	gnl|CDD|181352
NC_020990.1|WP_015508004.1|5323304_5325887_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015507998.1|5311797_5312550_-|precorrin-4-C(11)-methyltransferase	unknown	unknown	gnl|CDD|225430
NC_020990.1|WP_003947709.1|5303182_5306791_-|cobaltochelatase-subunit-CobN	unknown	unknown	gnl|CDD|235663
NC_020990.1|WP_003947695.1|5322909_5323101_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003947697.1|5320935_5321673_-|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NC_020990.1|WP_003947693.1|5325960_5327370_-|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl|CDD|273198
NC_020990.1|WP_015507999.1|5312614_5313853_-|bifunctional-cobalt-precorrin-7-(C(5))-methyltransferase/cobalt-precorrin-6B-(C(15))-methyltransferase	unknown	unknown	gnl|CDD|225150
NC_020990.1|WP_037630424.1|5322210_5322873_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NC_020990.1|WP_003947705.1|5311043_5311814_-|cobalt-precorrin-6A-reductase	unknown	unknown	gnl|CDD|236144
NC_020990.1|WP_008409264.1|5314810_5316022_-|cardiolipin-synthase-B	unknown	unknown	gnl|CDD|234967
NC_020990.1|WP_003947700.1|5316252_5317251_+|polyphosphate-kinase-2	unknown	unknown	gnl|CDD|213852
NC_020990.1|WP_015508001.1|5317990_5318848_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003947692.1|5327612_5328080_+|RDD-family-protein	unknown	unknown	gnl|CDD|377640
NC_020990.1|WP_003947698.1|5319207_5320200_+|dihydroxyacetone-kinase-subunit-DhaK	unknown	unknown	gnl|CDD|376910
NC_020990.1|WP_015507997.1|5307403_5308741_+|precorrin-3B-synthase	unknown	unknown	gnl|CDD|274131
NC_020990.1|WP_003947706.1|5309356_5310922_+|precorrin-2-C(20)-methyltransferase	unknown	unknown	gnl|CDD|381173
NC_020990.1|WP_003947691.1|5328175_5328874_-|DUF4191-domain-containing-protein	unknown	unknown	gnl|CDD|379389

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_015508000.1|5313997_5314675_-|DoxX-family-membrane-protein	gnl|CDD|311556	pfam07681, DoxX, DoxX. These proteins appear to have some sequence similarity with pfam04173 but their function is unknown.	0.00967624
NC_020990.1|WP_015508002.1|5320258_5320921_+|dihydroxyacetone-kinase-subunit-L	gnl|CDD|237723	PRK14479, PRK14479, dihydroxyacetone kinase; Provisional.	2.04606e-54
NC_020990.1|WP_003947698.1|5319207_5320200_+|dihydroxyacetone-kinase-subunit-DhaK	gnl|CDD|376910	pfam02733, Dak1, Dak1 domain. This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.	7.88315e-146
NC_020990.1|WP_015507998.1|5311797_5312550_-|precorrin-4-C(11)-methyltransferase	gnl|CDD|225430	COG2875, CobM, Precorrin-4 methylase [Coenzyme metabolism].	3.61176e-125
NC_020990.1|WP_003947709.1|5303182_5306791_-|cobaltochelatase-subunit-CobN	gnl|CDD|235663	PRK05989, cobN, cobaltochelatase subunit CobN; Reviewed.	0
NC_020990.1|WP_003947697.1|5320935_5321673_-|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	2.01391e-39
NC_020990.1|WP_003947693.1|5325960_5327370_-|type-I-glutamate--ammonia-ligase	gnl|CDD|273198	TIGR00653, Glutamine_synthetase, glutamine synthetase, type I. Alternate name: glutamate--ammonia ligase. This model represents the dodecameric form, which can be subdivided into 1-alpha and 1-beta forms. The phylogeny of the 1-alpha and 1-beta forms appears polyphyletic. E. coli, Synechocystis PCC6803, Aquifex aeolicus, and the crenarcheon Sulfolobus acidocaldarius have form 1-beta, while Bacillus subtilis, Thermotoga maritima, and various euryarchaea has form 1-alpha. The 1-beta dodecamer from the crenarcheon Sulfolobus acidocaldarius differs from that in E. coli in that it is not regulated by adenylylation. [Amino acid biosynthesis, Glutamate family].	0
NC_020990.1|WP_015507999.1|5312614_5313853_-|bifunctional-cobalt-precorrin-7-(C(5))-methyltransferase/cobalt-precorrin-6B-(C(15))-methyltransferase	gnl|CDD|225150	COG2241, CobL, Precorrin-6B methylase 1 [Coenzyme metabolism].	9.74173e-72
NC_020990.1|WP_037630424.1|5322210_5322873_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.22473e-11
NC_020990.1|WP_003947705.1|5311043_5311814_-|cobalt-precorrin-6A-reductase	gnl|CDD|236144	PRK08057, PRK08057, cobalt-precorrin-6x reductase; Reviewed.	2.89812e-105
NC_020990.1|WP_008409264.1|5314810_5316022_-|cardiolipin-synthase-B	gnl|CDD|234967	PRK01642, cls, cardiolipin synthetase; Reviewed.	5.31303e-91
NC_020990.1|WP_003947700.1|5316252_5317251_+|polyphosphate-kinase-2	gnl|CDD|213852	TIGR03707, PPK2_P_aer, polyphosphate kinase 2, PA0141 family. Members of this protein family are designated polyphosphate kinase 2 (PPK2) after the characterized protein in Pseudomonas aeruginosa. This family comprises one of three well-separated clades in the larger family described by pfam03976. PA0141 from this family has been shown capable of operating in reverse, with GDP preferred (over ADP) as a substrate, producing GTP (or ATP) by transfer of a phosphate residue from polyphosphate. Most species with a member of this family also encode a polyphosphate kinase 1 (PPK1). [Central intermediary metabolism, Phosphorus compounds].	1.283e-146
NC_020990.1|WP_003947707.1|5308733_5309360_+|precorrin-8X-methylmutase	gnl|CDD|181352	PRK08285, cobH, precorrin-8X methylmutase; Reviewed.	6.6404e-130
NC_020990.1|WP_003947692.1|5327612_5328080_+|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	2.42003e-12
NC_020990.1|WP_015507997.1|5307403_5308741_+|precorrin-3B-synthase	gnl|CDD|274131	TIGR02435, Precorrin-3B_synthase, precorrin-3B synthase. An iron-sulfur protein. An oxygen atom from dioxygen is incorporated into the macrocycle at C-20. In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	4.4254e-63
NC_020990.1|WP_003947706.1|5309356_5310922_+|precorrin-2-C(20)-methyltransferase	gnl|CDD|381173	cd11646, Precorrin_3B_C17_MT, Precorrin-3B C(17)-methyltransferase (also named CobJ or CbiH). Precorrin-3B C(17)-methyltransferase participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. This model includes CobJ of the aerobic pathway and CbiH of the anaerobic pathway, both as stand-alone enzymes and when CobJ or CbiH form part of bifunctional enzymes, such as in Mycobacterium tuberculosis CobIJ where CobJ fuses with a precorrin-2 C(20)-methyltransferase domain, or Bacillus megaterium CbiH60, where CbiH is fused to a nitrite and sulfite reductase-like domain. In the aerobic pathway, once CobG has generated precorrin-3b, CobJ catalyzes the methylation of precorrin-3b at C-17 to form precorrin-4 (the extruded methylated C-20 fragment is left attached as an acyl group at C-1). In the corresponding anaerobic pathway, CbiH carries out this ring contraction, using cobalt-precorrin-3b as a substrate to generate a tetramethylated delta-lactone.	1.08925e-116
NC_020990.1|WP_003947691.1|5328175_5328874_-|DUF4191-domain-containing-protein	gnl|CDD|379389	pfam13829, DUF4191, Domain of unknown function (DUF4191).	3.92239e-108

Protein sequences

>NC_020990.1|WP_003947700.1|5316252_5317251_+|polyphosphate-kinase-2
MESAAEQHGADRTEPGIHDADDTLLEGLSVDASRPEQPVLREADGTPVRTWRENYPYDRKLRRREYERRKRVLQIELLKMQSWVKETGARIVIVCEGRDAAGKGGTIKRFTERLNPRGARVVALDKPTEKEAGQWYFQRYIAHLPSPGEIVFFDRSWYNRAGVERVMGFCTEEQYEQFLVQAPLFEKMITSDGILLVKFWFSVSRSEQRTRFAIRQVDPVRQWKLSPTDLASLDLWDAYTRAKIEMFRATDTVWAPWTVVKTNDKRRGRLEAMRSLLLRVEYAAKDGGALGEGDPLIVGPADTLLEPGEEPTSLSPTPLADHDEGRGSHPDS
>NC_020990.1|WP_008409264.1|5314810_5316022_-|cardiolipin-synthase-B
MTMTEVAEDDPGAGGGEALAVRGRRLRRRLERLIGVAATEGNELTALRNGDEIFTAMLSAIREAEHTVDLMTFVYWKGEIARDFAAALCERAKAGVRVRLLLDGFGSRLIERHLLEEMDEAGVHVSWFRKPFLLSPFKQNHRCHRKVLVVDEKVAFTGGVGIAEEWCGDARNENEWRDTHVRLRGPAVDGVAAAFAQNWAECCDDLFDERDRFTAQPSSGGAVVQVVRGSASFGWQDMQTLLRVVLQSAEERVRIATAYFAPDAYFIDLLCATAARGVEVEILLPGPHTDKRVCQLAGQWHYDQLLGCGVRIHQYQPTMMHAKVITVDRVAALTGSTNINRRSLDHDEEVMLAVIDEEFTAVLDRHFDEDTEVSVEMQAGRYRRRSWLQRGREAMVVPIRRFL
>NC_020990.1|WP_015508000.1|5313997_5314675_-|DoxX-family-membrane-protein
MSGCGKVKAWQVPLRLVTGAFILHSGMEKWDGPDEQAQGVHGMARQTFPFLENIDAPRFLKLLAAGEIALGAALLTPMVPTRLAGAALTGFAGSLMAVYAQTPGLRKEGSVWPTPDGIGVSKDSWLLAIGLALTLSPHQKHHKHAQHVKHVKHAKGHGGCHKHHCHHEQGGHPGHHGHLKQAKLVAREAKEARRLAKGVSPDGHSHHHAHRHGPGHARKGCPAHH
>NC_020990.1|WP_015507999.1|5312614_5313853_-|bifunctional-cobalt-precorrin-7-(C(5))-methyltransferase/cobalt-precorrin-6B-(C(15))-methyltransferase
MTPISEQPAVTVVGIGADGWAGLGPAGREALAAAEVVVGGPRQLDLLPPECAGERVAWPSPLRPAVPKLLAEHAGRRLAVLASGDPMFYGIGRALAEEAGPAALHVLPHPSSVSYACARMGWAMQDVEVVSAVGRDPAALAGALHDGRRVLVLAPDAATPSRIAELLRERGYGPSRMTVLEQLGGPAEHRVDGVAGTWSAPAGDPLNVVAVECVRAAGTPRLPVVPGLPDDAYEHDGQLTKKYVRAATLAALAPAPGELLWDVGGGSGSIAVEWLRAHRACRAVSVERDPVRAGRITRNARALGVPRLKVVTGAAPGALAGLPVPDAVFIGGGLTGAGLLETCWAALPTGGRLVANTVTLESEALLTEWYRRHGGELTRLAVAQAVPVGSFTGWRQAMPVTQWSVTKPAEHT
>NC_020990.1|WP_015507998.1|5311797_5312550_-|precorrin-4-C(11)-methyltransferase
MTVYFIGAGPGAADLITLRGARTLAACQVCLYAGSLVPTELLAECPPDARLVDTAQLDLDRITAELVRAHEQGLDVARLHSGDTSVFSAVAEQMRRLDAAGVPYEVVPGVPAFAAAAAALKRELTVPTVGQTVILTRVAQRATPMPEGEDLATLGRSGALLVLHLATGYADRVVAELEPHYGADCPAAVVAFASRPEELVLRGTLADIAGQVREAGIRRTAVILVGRTLGAEQFRDSHLYSPDRDRDHVC
>NC_020990.1|WP_003947705.1|5311043_5311814_-|cobalt-precorrin-6A-reductase
MTTSADSAPPLVLVLGGTSESRRLAALLTRGAAGPLRVVSSLAGRVARPVLPEGEVRIGGFGGVAGLTAYLREERVAAVVDATHPFAGVMSFHAAEAAAGAGVPLLALRRPSWRQGPGDRWYPVASLEEAAALLPSLGRRVFLTTGRSGLGAFADAAPGLWFLLRSVDPPVGPGPEECEVLLDRGPFTLEGEREVLRTYGVEVLVTKDSGGEATAPKLTAARESGIPVVVVRRPPVPEGVPVVGTPEEAVAWLGGG
>NC_020990.1|WP_003947706.1|5309356_5310922_+|precorrin-2-C(20)-methyltransferase
MSTPAPGRLYGVGLGPGDPNLMTLRAVQVIADADVVAYHSARHGRSIARSIAAAHLRPDHIEEALVYPVTTGTTDHPGGYQGAMDDFYAACAERLAVHLDAGRTVAVISEGDPLFYGSYMHMHKRLAHRYPTEVIPGVTSVSAASARLGAPLVEGEEVLTILPGTLPEEELTARLAATDSAVVMKLGRTFPAVRGALEASGRLAEARYVERATMEGERTGHLADTDPESVPYFAVAVVPSRVAALPVDAPATGQAAVPAEEEAAAVPAGEVVVVGTGPAGPLWLTPETRGALAAAQDLVGYTTYLDRVPHRPGQIRHGSDNKVEAERAEFALDLARRGRRVAVVSGGDPGVFAMATAVLEAAAEGPYRDVPVRVLPGVTAANAAAARAGAPLGHDYAVISLSDRLKPWEVIAERLAAAARADLALALYNPGSRSRTWQVGKARDLLLEHRSPDTPVVLARDVGGPGERVRTVRLADLDPAEVDMRTLLIIGSSQTRAVRRTPDAPETVWTPRRYPEPTTGA
>NC_020990.1|WP_003947707.1|5308733_5309360_+|precorrin-8X-methylmutase
MFEYEKDGAAIYRESFATIRAEADLTGLPPDVAQVAVRMIHACGMTDLPRDLGHTPQVVARARRALRAGAPILCDANMVASGVTRKRLPADNEVICTLADPSVPELAARLGTTRSAAALELWRDRLDGAVVAVGNAPTALFRLLEMIEEGAPRPAAVIGVPVGFVGAAESKDALAAHPSGLDHLIVRGRRGGSAMAAAALNAIASETE
>NC_020990.1|WP_015507997.1|5307403_5308741_+|precorrin-3B-synthase
MPTPARGDACPGALRLHEAADGHLARVRIPGGLLQAPQAMALARAAEDLGDAHLDLTSRGNVQLRALPADAGRELAARLAEADLLPSPAHERIRNLVASPLSGLDDEGHADVTPLVPAVDAALLADPATTALSGRFLFALDDGRGDTAALDADVTMLATPDGDLALTLPGVPGSLRLPPDQAPAAAHAAALLFLAAARASGTRAWRVAELPPGQALSTATLTELAASVPGARTAPAPEPPAPYGGPRPGPTPPRAGRSALHALVPLGRLTAYQWRELAELAARHGAGTLRATPWRGIVVPGLTPDRAAEAAAGLARAGLVTGEGSPWEGVGACTGRPGCVKSLADVRADARAALDAAPGGLPVYWSGCERRCGHPRGTAWVDAVATGTGYDLAHRPADPAAEPRPAGRDVPAHRLPEALAAARRTPSTPRPTRHGAVRKEREQSV
>NC_020990.1|WP_003947709.1|5303182_5306791_-|cobaltochelatase-subunit-CobN
MILLLSTSDTDLLSARSAGGPVPYRFANPSRLPLDDLPELLDGADLVVVRLLGGVRAWQEGIDALLAQNRPVVVLTGEQAPDAQLMEASTVPIGVAAEAHAYLAHGGPANLEQLARFLSDTVLLTGHGFEAPAPAPSWGPLERTPAPEASGPLIAVLYYRAHHMSGNTGFVDTLCGAIEEAGGRALPLYVASLRSPEPELLAELGRADALVTTVLAAGGTKPAGASAGGDDESWDAGALAALDVPILQALCLTSSRADWEENDEGLSPLDAASQIAVPEFDGRLITVPFSFKELDADGLPVYVADTERAARVAGTAVRHARLRHLPNAEKRLALVLSAYPTKHSRIGNAVGLDTPASAVALLRRLIAEGYDFGDEAIPGLESGDGDELIYALIEAGGHDQDWLTEEQLARNPVRIPAADYRRWYGTLPAELREQVEEHWGPPPGEMFVDRSRNPEGDIVLAALRFGRLLILIQPPRGFGENPIAIYHDPDLPPSHHYLAAYRWIQARAEDGGFGADAMVHLGKHGNLEWLPGKNAGLSAACGPDAALGDLPLVYPFLVNDPGEGTQAKRRVHATLVDHLVPPMARAESYGDIARLEQLLDEYAAISSMDPAKLPAIRAQIWTLIQAAKLDHDLGLEARPDDDGFDDFLLHVDGWLCEVKDAQIRDGLHVLGSAPADEARVSLVLAILRARQIWGGTTALPGLREALGLDESAATRTTADEAEERARALVQAMDDAGWDPQAAARVAEGHGQAVADILTFAAREVVPRLAATTDELDHAVHALNGGFVPAGPSGSPLRGLVNVLPTGRNFYSVDPKAVPSRLAWETGQALADSLLERYRADHGDWPVSVGLSLWGTSAMRTSGDDVAEALALLGVRPVWDDASRRVTGLEAVPLEELGRPRVDVTLRISGFFRDAFPHTIGLLDDAVRLVAGLDEPDKDNHVAAHARADLAEHGDERRATTRIFGSRPGTYGAGLLQLIDSRDWRTDADLAEVYTVWGGYAYGRELEGREARAEMESAYRRIAVAAKNTDTREHDIADSDDYFQYHGGMVAAVRALKGTAPEAYIGDSTRPETVRTRTLVEETSRVFRARVVNPKWIEAMRRHGYKGAFELAATVDYLFGYDATTGVVADWMYDKLTETYVLDPENRAFLKEANPWALHGIAERLLEAESRGMWAEPDPEILAALRQAYLETEGDLESGRDEE
>NC_020990.1|WP_015508001.1|5317990_5318848_-|hypothetical-protein
MPKQSPDGNQEHEDGRAGRAPHAREAERPSRHEITEADRKGGPGHTVLLALALAIPAVKVAYTLGGGGAATDALMGMGPGNWWDVLLGMVLTTPLLACVLGVVASRVVFALFAAPGAVPRGDDPAARLRRAGLTVLNPVATGVVVACFIGPWWGLGTAVAAYLLRRGVVIEYRTGRRGRRHHDPHFAPPGWQRRLATGEQVVALTLSVVVLPLLGVVSALDGQAWTSVVRCEVSDGARTRVARLIELQRQGNGVVGWNLDQGEVSNGVGCTGVESRTVRAPWWRA
>NC_020990.1|WP_003947698.1|5319207_5320200_+|dihydroxyacetone-kinase-subunit-DhaK
MASYFENSSDALVPDALKGFARAHADLVTLDPEHGFLLSRTAAPSRRVALLSGGGAGHEPLHAGYVGRGMLDAACPGRVFASPHNRQVYAGSLAAARAEGVLHIVKNYTGDRINFGIAAERLAHRGVPCARVLIDDDLASDSADIASGRRGTGGTVLIEKILGAAADTGLGLAELQELGTRLAARCRTLAVASAAHTAPTTGEPAFPLAAGELEYGVGIHGERAQQTVPREPLNGLVERMTTALLDALAPEGPVIALVNGLGAVTPLELYAVHGELATLLDARGTDLARALVGDYITALDMRGFSVTLLAADEEILRLYDAPVHTAALRW
>NC_020990.1|WP_015508002.1|5320258_5320921_+|dihydroxyacetone-kinase-subunit-L
MTTSTSHDATATDGWMRRFAESAHATETRLTSLDQQVGDGDFGTNLTAGADAALRRLDQLPGGDTDPAAPLEAAATAFLDEVGGTSGPLFGLLLQSLAAAVAGSGPTTAAYAEGVTDGLAAIRRVGDAAPGDKTLVDALTPAAEALRATPAGTPPDQALAAAADAAWEGVRSTARLRARMGRSSYLGERAEGIPDPGAVGVGLLFASAQGVVTDLDTHLG
>NC_020990.1|WP_003947697.1|5320935_5321673_-|HAD-family-phosphatase
MTTKAHPLLSWSPEAVVFDCDGTLMDTERHWQDARSQVFRQFGLRPLPGFAERAKGVHYTDCGRLMAEESDKPHLAGELTESLLTHFMELVADDPVTMPGAAEFVRRLSGRLPLAVASNCPLEVVEMSLERAGLLHHFRHVVVPDEPSTGAAPGSATVRPKPWPDVYARAAWLCGADPDSTLAVEDSLTGIESARRAGLRVLGVGPRPGEEDASRADLWVTTLHSPVLLAWVRAHVPQQGGSAEG
>NC_020990.1|WP_037630424.1|5322210_5322873_+|TetR/AcrR-family-transcriptional-regulator
MQERARATRRSLLEAAALLFAEQGYAGTSVNDISARSGRTSGAVYFHYASKEGLALAVVQHRFATWPGLAARYTDRAEPPLEKLVALSFDIAHALAEDPLARAGARLWAERDTIDAPLPDPFALWTTATTRLLAQARTAGHLTPHIRPAPTARSLVRAFFGLCTLTEALEGPTAVTARLTDWWLLTLGSLQQRPDAAGVLGRVRARGGLLGERMGAACGE
>NC_020990.1|WP_003947695.1|5322909_5323101_-|hypothetical-protein
MTSLVLVPLVGLAALCLLIAVLSAVYLWSADSALRVRAWRLLEALLRAAGRDRHDSARASDDS
>NC_020990.1|WP_015508004.1|5323304_5325887_+|hypothetical-protein
MATAASGAALERLKYRLGRLYREAGEPSLRVLSQRTERAISHTTVGTVLHCESLPRWGQLELVVEALGGDLGELRTLWIAVRDETSPLDQPTPPTCELESEEALDTAAPEQLGGQNGATPRQRVRPDGEPGGGGSIDLPRPLADWQPERLGVHAAITDPLRTAVQGFALPEYVVRSHDHEVRRLLGEAASGGAPTLIVLSGYSCTGKTRTAYEAVAACLADWDLVYPKDADSLCRLLAADALGPRTVLWLNEAQELLGGTGGETAASALRRRLEQPGPLVAVATLWPGHRKELTDRPAEGPDRHPQVRALLAAAHVITVPAAFDGPALERLGETADGALAVAARTAPDGHITQTLAGGPALVQWYEQADGPEDCYGKAVVTAAMDARRLGHTAPLPLALLEAAAPGYLTDTQRAAAPEGWFAAASAFARTMVKDVVAALGDVPHDHGMGARPGVCRLADYLDHYARTARHACFPPASFWQAVEHHAATASDLYELAEAAERRGRLRLSATLLSRAAEAGHGPAWESIVTMMTYRGLAEEAETLARSVLLRSGDPEPILAVAWTLSEFQDPDSAERLMREAATTGRVSALLSLASVLPGGPERTEVLTKAVALGDPEAHFLLAEVHRDAGDTTEYERLLLLGASAGDRNAVSEQVRVKWRAGEWGEAERLARSVAEQDDGFELATLAMDRFKEGDWAEGERLAWAVMELAERDAAGAAKLSWPGAIIAAVLTLLGHCDEDEAEVLLHRLAESRNPQTWAVAASCLETQDPDRAEILHGRAAERGNLYALERLAMMRRLRGAADAERTHRAAVDAGGGVRLLVDLWEEEGRAQEADQAYRYGLETDGSLCEPWSFPRLELPR
>NC_020990.1|WP_003947693.1|5325960_5327370_-|type-I-glutamate--ammonia-ligase
MFQNADDAKKFIADEDVKFVDVRFCDLPGVMQHFTIPAKAFDADEELAFDGSSIRGFQAIHESDMSLRPDLSTARVDPFRRDKTLNINFFIHDPITGEQYSRDPRNIAKKAEAYLASTGIADTAYFGPEAEFYVFDSVRFETSANQGFYHIDSEAGAWNTGSEVENRGYKVRYKGGYFPAPPVDHFADLRAEISLELEQAGLEVERQHHEVGTAGQAEINYKFNTLLAAADDLMLFKYIVKNVAWRNGKTATFMPKPIFGDNGSGMHVHQSLWSGGTPLFYDEQGYAGLSDTARYYIGGILKHAPSLLAFTNPTVNSYHRLVPGFEAPVNLVYSQRNRSAAMRIPITGSNPKAKRVEFRAPDPSSNPYLAFSALLLAGLDGVKNKIEPAEPIDKDLYELAPEEHAGVPQVPTSLPAVLDALEADNEYLQAGGVFTPDLIDTWIDYKRTQEIAPIQLRPHPHEFELYFDL
>NC_020990.1|WP_003947692.1|5327612_5328080_+|RDD-family-protein
MDNRQAIGSWLSGPRAAAEEMGADFGYRGERLGLPEHGPGSVAPVGRRFGALAIDWALCMLIAYGLFSGGDAQSTGNWALGILLVMNILTVGTVGCTPGKLLLRLRVVSEQGGRLGPGWTVVRSALLCLGVPALIWDRDSRGLHDRLGRAVQIRV
>NC_020990.1|WP_003947691.1|5328175_5328874_-|DUF4191-domain-containing-protein
MASKDNAASSANPGRIKQIAQTYKMAKRVDPKIGWVIAAVGIVTFGVFLAIGFLVGHPVYLGILGFVLAFLAMAIIFGRRAEKAAFSQMEGQPGAAAAVLDNIGRGWTTTPAVAVNRSQDVVHRAVGKAGIVLVAEGNPNRVKGLLASEKKKMARIVVDVPVHDIVVGTGEGQTPLKKVRTTMLKYPRVLTGPQVTATNDRLRALGDLMSNMPVPKGPMPKGARMPRGPKMR

Crispr_ID: NC_020990_30

• CRISPR_ID: NC_020990_30
• CRISPR_location: 5367154-5367365
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_020990_30

Consensus_repeat	Method
CGGGGACCACCCCCGCACACGCGGGGAGCACGCCGTCG	PILER-CR
GTGCTCCCCGCGTGTGCGGGGGTGGTCCC	CRT

spacers of NC_020990_30

>30.1|5367192|23|NC_020990|PILER-CR
GGGGTACGCCATCACCGGGCGGC
>30.2|5367253|23|NC_020990|PILER-CR
GGCCAGGTGGGCGATGGCCTGCT
>30.3|5367183|32|NC_020990|CRT
GAGGGGTACGCCATCACCGGGCGGCCGCCGGC
>30.4|5367244|32|NC_020990|CRT
CGGGCCAGGTGGGCGATGGCCTGCTCGACGTC
>30.5|5367305|32|NC_020990|CRT
CGTTCGAGGAGATCCGCTGTGGCCATCGTGTG

CRISPR arrays and Neighbor proteins around NC_020990_30

CRISPR arrays

The CRISPR arrays of NC_020990_30

>merge|NC_020990|30|5367154-5367365|PILER-CR,CRT
GTGCTCCCCGCGTGTGCGGGGGTGGTCCCGAGGGGTACGCCATCACCGGGCGGCCGCCGGCGTGCTCCCCGCGTGTGCGGGGGTGGTCCCCGGGCCAGGTGGGCGATGGCCTGCTCGACGTCGTGCTCCCCGCGTGTGCGGGGGTGGTCCCCGTTCGAGGAGATCCGCTGTGGCCATCGTGTGGTGCTCCCCGCGTACGCAGGGGCCCCCGG

>NC_020990|30|7|5367154-5367306|PILER-CR
GTGCTCCCCGCGTGTGCGGGGGTGGTCCCGAGGGGTAC	GCCATCACCGGGCGGCCGCCGGC
GTGCTCCCCGCGTGTGCGGGGGTGGTCCCCGGGCCAGG	TGGGCGATGGCCTGCTCGACGTC
GTGCTCCCCGCGTGTGCGGGGGTGGTCCCCG

>NC_020990|30|4|5367154-5367365|CRT
GTGCTCCCCGCGTGTGCGGGGGTGGTCCC	GAGGGGTACGCCATCACCGGGCGGCCGCCGGC
GTGCTCCCCGCGTGTGCGGGGGTGGTCCC	CGGGCCAGGTGGGCGATGGCCTGCTCGACGTC
GTGCTCCCCGCGTGTGCGGGGGTGGTCCC	CGTTCGAGGAGATCCGCTGTGGCCATCGTGTG
GTGCTCCCCGCGTACGCAGGGGCCCCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_030306784.1|5356236_5356938_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|369777
NC_020990.1|WP_003947655.1|5370573_5371548_+|carbohydrate-kinase-family-protein	unknown	unknown	gnl|CDD|238917
NC_020990.1|WP_003947660.1|5364864_5366067_-|quinolinate-synthase-NadA	unknown	unknown	gnl|CDD|236489
NC_020990.1|WP_015508013.1|5371597_5372974_-|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl|CDD|224029
NC_020990.1|WP_003947664.1|5358832_5359111_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_094030682.1|5359184_5360603_+|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NC_020990.1|WP_003947651.1|5376125_5376524_+|cytochrome-c-oxidase-subunit-4	unknown	unknown	gnl|CDD|378833
NC_020990.1|WP_003947661.1|5361547_5364745_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NC_020990.1|WP_003947656.1|5370188_5370398_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003947667.1|5355942_5356158_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003947662.1|5360599_5361283_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_020990.1|WP_003947649.1|5378048_5378450_-|hypothetical-protein	unknown	unknown	gnl|CDD|225971
NC_020990.1|WP_008406965.1|5376706_5377927_+|L,D-transpeptidase	unknown	unknown	gnl|CDD|380079
NC_020990.1|WP_008406956.1|5367438_5368467_-|cation-transporter	unknown	unknown	gnl|CDD|223604
NC_020990.1|WP_003947652.1|5374392_5376129_+|cytochrome-c-oxidase-subunit-I	unknown	unknown	gnl|CDD|238832
NC_020990.1|WP_003947657.1|5368589_5370035_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003947653.1|5373430_5374396_+|cytochrome-c-oxidase-subunit-II	unknown	unknown	gnl|CDD|224537
NC_020990.1|WP_003947666.1|5357132_5357753_-|DUF3043-domain-containing-protein	unknown	unknown	gnl|CDD|378611
NC_020990.1|WP_003947665.1|5358038_5358815_+|PspA/IM30-family-protein	unknown	unknown	gnl|CDD|224755
NC_020990.1|WP_003947659.1|5366382_5366739_+|iron-sulfur-cluster-assembly-accessory-protein	unknown	unknown	gnl|CDD|272875

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_030306784.1|5356236_5356938_-|methyltransferase-domain-containing-protein	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	9.13881e-17
NC_020990.1|WP_003947655.1|5370573_5371548_+|carbohydrate-kinase-family-protein	gnl|CDD|238917	cd01942, ribokinase_group_A, Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.	2.50135e-62
NC_020990.1|WP_003947660.1|5364864_5366067_-|quinolinate-synthase-NadA	gnl|CDD|236489	PRK09375, PRK09375, quinolinate synthase NadA.	2.15985e-155
NC_020990.1|WP_015508013.1|5371597_5372974_-|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	1.11664e-110
NC_020990.1|WP_008406965.1|5376706_5377927_+|L,D-transpeptidase	gnl|CDD|380079	pfam17964, Big_10, Bacterial Ig domain. This entry represents a bacterial Ig-like domain found associated with transpeptidase domains.	6.56159e-47
NC_020990.1|WP_094030682.1|5359184_5360603_+|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.13525e-43
NC_020990.1|WP_003947651.1|5376125_5376524_+|cytochrome-c-oxidase-subunit-4	gnl|CDD|378833	pfam12270, Cyt_c_ox_IV, Cytochrome c oxidase subunit IV. This family of proteins is found in bacteria. Proteins in this family are approximately 140 amino acids in length. This family is the fourth subunit of the cytochrome c oxidase complex. This subunit does not have a catalytic capacity but instead, is required for assembly and/or stability of the complex.	1.88669e-62
NC_020990.1|WP_003947661.1|5361547_5364745_+|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_020990.1|WP_003947662.1|5360599_5361283_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.12618e-65
NC_020990.1|WP_003947649.1|5378048_5378450_-|hypothetical-protein	gnl|CDD|225971	COG3437, COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms].	0.00482668
NC_020990.1|WP_008406956.1|5367438_5368467_-|cation-transporter	gnl|CDD|223604	COG0530, ECM27, Ca2+/Na+ antiporter [Inorganic ion transport and metabolism].	7.52271e-15
NC_020990.1|WP_003947652.1|5374392_5376129_+|cytochrome-c-oxidase-subunit-I	gnl|CDD|238832	cd01662, Ubiquinol_Oxidase_I, Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. The number of subunits in ubiquinol oxidase varies from two to five. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme and a copper ion. It also contains a low-spin heme, believed to participate in the transfer of electrons from ubiquinol to the binuclear center. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from ubiquinol on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I. It is generally believed that the channels contain water molecules that act as 'proton wires' to transfer the protons. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electrons are believed to be transferred directly from ubiquinol (the electron donor) to the low-spin heme, and directly from the low-spin heme to the binuclear center.	0
NC_020990.1|WP_003947653.1|5373430_5374396_+|cytochrome-c-oxidase-subunit-II	gnl|CDD|224537	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion].	1.1164e-52
NC_020990.1|WP_003947666.1|5357132_5357753_-|DUF3043-domain-containing-protein	gnl|CDD|378611	pfam11241, DUF3043, Protein of unknown function (DUF3043). Some members in this family of proteins with unknown function are annotated as membrane proteins. This cannot be confirmed.	3.08562e-66
NC_020990.1|WP_003947665.1|5358038_5358815_+|PspA/IM30-family-protein	gnl|CDD|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	7.40444e-28
NC_020990.1|WP_003947659.1|5366382_5366739_+|iron-sulfur-cluster-assembly-accessory-protein	gnl|CDD|272875	TIGR00049, Uncharacterized_protein_in_nifU_5'region, Iron-sulfur cluster assembly accessory protein. Proteins in this subfamily appear to be associated with the process of FeS-cluster assembly. The HesB proteins are associated with the nif gene cluster and the Rhizobium gene IscN has been shown to be required for nitrogen fixation. Nitrogenase includes multiple FeS clusters and many genes for their assembly. The E. coli SufA protein is associated with SufS, a NifS homolog and SufD which are involved in the FeS cluster assembly of the FhnF protein. The Azotobacter protein IscA (homologs of which are also found in E.coli) is associated which IscS, another NifS homolog and IscU, a nifU homolog as well as other factors consistent with a role in FeS cluster chemistry. A homolog from Geobacter contains a selenocysteine in place of an otherwise invariant cysteine, further suggesting a role in redox chemistry. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	6.53498e-51

Protein sequences

>NC_020990.1|WP_003947659.1|5366382_5366739_+|iron-sulfur-cluster-assembly-accessory-protein
MSVQDEKTTVSDGILLSDAAAAKVKALLDQEGREDLALRVAVQPGGCSGLRYQLFFDERSLDGDVVKDFGGVKVVTDRMSAPYLGGASIDFVDTIEKQGFTIDNPNATGSCACGDSFS
>NC_020990.1|WP_003947660.1|5364864_5366067_-|quinolinate-synthase-NadA
MTTAQPRTDLDVQPTPLALLLLGREADPASERGVDCPGDLPSPSDPDLVARARAAKEKLGDKVFVLGHHYQRDEVIQFADVTGDSFKLARDAAARPEAEYIVFCGVHFMAESADILTSDEQKVVLPDLAAGCSMADMATAEQVAECWDVLSEAGVADQVVPVAYMNSSANIKAFTGKHGGTICTSSNAKRALEWAFEQGQDPATTKILFLPDQHLGRNTAVRDLGMSLEDCVVYNPHKPNGGLTAEQLRDARMILWRGHCSVHGRFSLESVEDVRARVPGVNVLVHPECKHEVVAAADLVGSTEYIIKTLEAAPRGSKWAIGTELNLVRRLANRFAEEDKEIVFLDRTVCFCSTMNRIDLPHLVWTLESLAEGTLVNRIEVDKETEDFAKLALERMLALP
>NC_020990.1|WP_003947661.1|5361547_5364745_+|efflux-RND-transporter-permease-subunit
MSWLSRFSLAQRALIGLMSIIALLFGAIAIPQLKQQLLPSIELPMVSVLAPYPGASPDVVEKQVVEPLEKSIDAVEGITGITATASEGNAVLMAQFDFGSADTQQLVADIQQAVNRSRAMLPDDVDPQVVAGSTDDIPTVVLAVTSDKDQQALAGQLERTVVPSLESIDGVGQVSVDGVRELQIAVTPDDADLAKAGLSSADLVQALQAAGATVPAGSFDEKGENRTVQVGGGFTSVKQIEDLRIAPAAGGQGGQGGPGAQAGPGDAGKAPAPVRLGSVAKVEQQQATATSLTRTNGEPSLAVVVTMDRDGSAVAISDAVAEKLPELRADLGDSSELTVVSDQGPAVAKSIEGLTTEGALGLVFAVVIILVFLASIRSTLVTAVSIPLSVVLALIVLWTRDLSLNMLTLGALTIAIGRVVDDSIVVLENIKRHLGYGEERKEAILTAVKEVAGAVTSATLTTVAVFLPIGLVGGMVGELFGSFSLTVTAALLASLLVSLTVVPVLSFWFLRAPKGTPEDAEAARAAAEEKEARSRLQRLYVPILKFATRRRLTSLAIAVAVLLGTFGMAPLLKTNFFDQGEQDVLSVKQELAPGTSLAATDEAAEKVEALLKETEGVEDYQVTIGSSGFMAAFGGGTDTNQASYQVKLADSASSETVQKALDKGLAGLDGIGDTRVAAGDGFASQDLSVVVKASEADVLAKASEQVREEVAKLDDVTDVQSDLSQSVPRISVSANEKAAAAGFTDASLGQVVAQSVRGTTAGQVVLDDAERDIVVKSAKPAETLAELRALPLGPVKLGQIADVELVDGPVSMTRIDGSRAATVTARPTADNTGAVTAELQTKINALELPEGATATIGGVSADQDEAFGQLGLAMLAAIAIVFMLLVATFRSLVQPLILLVSIPFAATGAVGLLIATGTPMGVPAMIGMLMLIGIVVTNAIVLIDLINQYRDKGYGIIEAVIEGGRHRFRPILMTALATIFALIPMALGVTGEGGFIAQPLAVVVIGGLITSTVLTLVLVPTLYAMVELRKERRAAKKAAKRDGKADVPGQGGTPAEEQTPEPARS
>NC_020990.1|WP_003947662.1|5360599_5361283_+|response-regulator-transcription-factor
MTIRVLLADDQALLRSAFRVLVDSEPDMEVVGEAADGDQALALARAARPDVVLMDIRMPGTDGLAATRLISADPALDTVRVVMLTTFEVDEYVVRALRAGASGFLGKGSEPAELLGAIRVAHAGEALLSPAATKGLIASFLAQSGHGADERPGAREERLAALTGREREVLVHVAGGLSNDEIAGRLQVSPLTVKTHVNRAMAKLGARDRAQLVVTAYETGLVRPRTA
>NC_020990.1|WP_094030682.1|5359184_5360603_+|two-component-sensor-histidine-kinase
MRPPRNGVRTPPDGAVRRPGRAERYRQRTPEGPVSPTPTTPAAPPRRAYARLRRKARAHPRLLDAVLAVGVLLCMLASSLTDPHHPDGPTWQAAPPDATGFTLMALGAAALVLRRRAPRTVLAATSAASLAVLVSSDPRTPVVMSAAVALYTVAARTDRPTTWRIGLLTSAGLTAGAMLCGNLPWYAQENFGIFAWLGLAAAAGDAVRSRRAYITAIHERADRAERTREEEARRRVAEERLRIARDLHDVVAHHIALVNVQAGVAAHVMDRRPDQAKEALAHVREASRSALDELRATVGLLRQSGDPEAPTEPAPGLARLDDLAERFRNAGLPVEIACPDRGDPLPAAVDLAAYRVVQEALTNVHKHAGPGARAEVSIVPVDGQVEITVLDGGPAATPAPGAAPAEPPPGGGHGLLGMRERVTALGGTCTAGPRFGGGFRVHAILPAQGAAPANRPPAPVPPARTDAPKDGR
>NC_020990.1|WP_003947664.1|5358832_5359111_+|hypothetical-protein
MIVRIMGEGQVKLADSHFAELNALDDELLTEMENGDGPGFRATLTALLDKVRELGTPLPDDSLEPSELILPAPEASLEEVRELLSDDGLIPG
>NC_020990.1|WP_003947665.1|5358038_5358815_+|PspA/IM30-family-protein
MGMIFRAKANKALDRAEDPRETLDYSYQKQLELLQKVRRGVADVATSRKRLELQLNQLQKKSSDLEGQGRKALALGREDLAREALSRRAALQGQITDLETQHQTLQGEEEKLTLAAQRLQAKVDAFRTKKETIKATYTAAQAQTRIAESFSGISEEMSDVGVAIQRAEDKTAQLQARSGAIDELLASGALDDQSGLQKDDIQLELDRLSGGSDVELELQRMKAELAGGPSGGQQAIEGGAEGEKDRQQPEDTPRFEKN
>NC_020990.1|WP_003947666.1|5357132_5357753_-|DUF3043-domain-containing-protein
MRPHTVRLGFVFRSRANSEKAPAAQAAPSTEPRDPQAPKGRPTPKRAQAQSQRRSVTNTQMSRKEASRKQRDARRAEMARQREALNNGDERYLPARDKGPVRKFARNYVDSRFAVAEFFLPFAVVILILSMIRVPQLQNIALLLWMALIVLIVIDSVVTSMKLKRALRERFEGQPMKGAVMYALMRTLQMRRLRLPKPMVKRGEQP
>NC_020990.1|WP_030306784.1|5356236_5356938_-|methyltransferase-domain-containing-protein
MVARQLDEQLAARFAVGRRLRVLDVGMGEGRQALRLARLGHQVTGVESDPALVAAAEEALAKEPEGIRERFRPVVGDGHDTGVHFLPGSFDVVLCHGVLMRVESPDALLAGLGRMLAPGGLLSLLVRNADALALCAGLAGDWRGALDAFGAESAAEGPVRADRLAPLTAALAGIGAPLERWYGVRVLAGRASDGPVPVDEAEFQALLAAEERAGRTDPYRSVAALLHLCGVRG
>NC_020990.1|WP_003947667.1|5355942_5356158_+|hypothetical-protein
MVPWTWRFEKADGTEVSPSVEPDEFSTQGDAESWLGEYWKELLEGGVEQVRLFEDTTEIYGPMSLSEAQTA
>NC_020990.1|WP_008406956.1|5367438_5368467_-|cation-transporter
MLAGQWPLGWSVAVVCLAGALTVACSVRLAGLGDVLADRTGWGEALFGAVLFGLVTSLSGIVMTAVSAADDQPELAYSNAVGGIAAQTLAVVAADAFYRRVNLEHAAASLQNLLFGCLLTGLLGLALMASFSPDVTVAGVHPASFVLILFYLGGLHLIHKNTEPMWRAVRTRETVWDVPQSDGAFAQRSTPRLWTEFVVIAGIVVVAGWAVTQAAEGILSATTLRAGFVGAVILGVINGLPEAVTSIAAVRRGAITLAFAAIIGGNSLDVLNLAVGDFAYRGGSLYHAAGNDELFLTSAALVMTTVVLGGLLIRQERGWFRLGFDGALLVVIYAATVTILAF
>NC_020990.1|WP_003947657.1|5368589_5370035_-|hypothetical-protein
MSTERSDQEQERPRRRSPMAVASVAAAVLIVGGGGAYLVTAAASGDAKDGGQPAGADAGDAPPPLELDGHTRGVAPGEPDPGGGVYQAKGKLPEGPGEAAVQRFEAPRETDVAKLAKALGVSGEPRTEGGSWLVGTAKDGQGPLLRVNKQAPGTWSYQGHTPPHGDDCPKGKMCANSSDGAQEDDPVGEKAAKSAAAPVLKALGQDDAKLDAGQVSDGVRVVNAQPVVDGLPTYGWSTGVRVAPDGSLAGGSGQLSEPVKGDTYPVLTAKQALAQLNGASKGDGKVGIGGCASAAPLDGAESADGSAPPKDPCTPGGDAPEREPVAVRGAVFGLSAQFVSGRQALVPSWLFEVRPEGHDRSHTVTRPAVDPEYLTPPATPEKPGTDPGASPGQDRKLSEAESYRADGKELTVRFWGGVCEKYTAEAEEKSGSVTVRITSEPQEPGKVCVKMAKQLTAKVTLDKPLGDREVVDEDGSAVPRD
>NC_020990.1|WP_003947656.1|5370188_5370398_-|hypothetical-protein
MSNQSVKDAGPLELDHGFEVLRGDCARMSKDWPAPHGAPRTAVPLSAIHGVRVTPASVRLIDGMSEYGD
>NC_020990.1|WP_003947655.1|5370573_5371548_+|carbohydrate-kinase-family-protein
MRIAVTGSIATDHLMTFPGRFADQLVADQLHTVSLSFLVDQLDVRRGGVAANICFGMGQLGTAPVLVGAAGADFDEYRAWLDRHGVDTGSVRISEVLHTARFVCTTDADHNQIGSFYTGAMSEARLIELQAVAERVGGLDLVLIGADDPEAMLRHTEECRSRNIPFAADFSQQIARMDGAEIRTLLDGATYLFSNEYEKGLIESKTGWSDEEILGRVGHRVTTLGSRGVRIERAGEDPVEVGVPEEETKADPTGVGDAFRAGFLSGLSWGVSLERAAQVGCMLATLVIETVGTQEYTLGRVPFMDRFTKAYGHDAAAEVQAHLV
>NC_020990.1|WP_015508013.1|5371597_5372974_-|aminotransferase-class-V-fold-PLP-dependent-enzyme
MPYFDAASAAPLHPTARQALLASLDEGWADPARLYREGRRARLLLDAARESAAESVGCRPDELVFTPSGTQAVHWGMAGALAGRRRTGRHLVVSEVEHSSVLHTAESFEAEGGEVDRVGVESTGRVPAQAFAAALRADTALACLQSANHEVGTAQPVEEVAEACRAATVPLLVDAAQSLPWGPVPGPWSLLTGSAHKWGGPPGVGLLAVRKGTRFAPRGPADERESGRAPGFGNLPAVVAAAASLRAVRAEAEAEGVRLRELVDRIRLRLPELVDDMEVVGDPVHRLPHLVTFSCLYVDGEALLHELDRAGFAVSSGSSCTSSTLTPSHVLRAMGVLSEGNVRVSLPHGTPATDVDHFLTVLPEAVRAVRARLGAPGAEPPAVQEALVVDALGRRCPVPVIELAKVIDRVPVGGTVTVLSDDEAARLDIPAWCRMREQEYVGEEPAVRGTAYQVRRLV
>NC_020990.1|WP_003947653.1|5373430_5374396_+|cytochrome-c-oxidase-subunit-II
MSPNGSDRSSRRPMRRKLPQVLTAGLILATATGCTYEDFPRLGMPTPVTEEAPIILSLWQGSWAAALVTGVLVWALILWACFAYRRTRTKIEVPPQTRYNMPLEALYTVVPVLIVSVFFFFTARDESKLLELSDEPAHTINVVGFQWSWAFNYVEDVDGDTATGDAKKDKDLKAIPDRFKDAFPEGAEGVHAVGTPGERNPQNGNPGPTLWLPKGEKVRFVLTSRDVIHSFWVVPFLMKQDVIPGHTNSFEVTPNKEGTFMGKCAELCGVDHSRMLFNVKVVSPERYQQHLEELREKGQTGYVPAGIEQTDPARNSEKNQL
>NC_020990.1|WP_003947652.1|5374392_5376129_+|cytochrome-c-oxidase-subunit-I
MSILNEPQGDAAADDSYENELPVRRKQPGNVVVKWLTTTDHKTIGTLYLVTSFIFFCIGGLMALVMRAELARPGTQIISNEQFNQAFTMHGTIMLLMFATPLFNGFANWIMPLQIGAPDVAFPRLNMFAYWLYLFGSLIAVAGFLTPQGAADFGWFAYSPLSDAVRSPGVGADMWIMGLALSGFGTILGSVNFITTIICMRAPGMTMFRMPIFTWNVLLTGVLVLLAFPVLAAALFALEADRKFGAQVFSPENGGALLWQHLFWFFGHPEVYIIALPFFGIVSEIIPVFSRKPIFGYMGLVGATIAIAGLSVTVWAHHMYVTGGVLLPFFSFMTFLIAVPTGVKFFNWIGTMWKGSLSFENPMLWSVGFLVTFLFGGLTGVILASPPLDFHVSDSYFVVAHFHYVVFGTVVFAMFAGFHFWWPKFTGKMLDERLGKITFWTLFIGFHGTFLVQHWLGAEGMPRRYPDYLAADGFTALNTVSTISSFLLGLSLLPFFYNVWKTAKYGKKIEVDDPWGYGRSLEWATSCPPPRHNFLTLPRIRSESPAFDLHHPEIAAMDHLEDHDPQPKAVAGTKEAGK
>NC_020990.1|WP_003947651.1|5376125_5376524_+|cytochrome-c-oxidase-subunit-4
MKIQGKMFIWLSAFILLVAVVYGLWSREPAGTTALFLAFGLSIMVGFYLAFTARRVDAMAQDDKEAEVADEAGEVGFFSPHSWQPLSLGIGGALAFLGVVFDWWLMYFSAPMLLIGLWGWIYEYYRGENQNQ
>NC_020990.1|WP_008406965.1|5376706_5377927_+|L,D-transpeptidase
MLVVALGAGATACGSSETHPLAAAPYDAAQDVAISAGGRTKADPDKPLEVTATGKGRLTDVVAVDASGRRVAGELSADGTRWRTTGPLAAAARYTVTASTENGDGGPGRRTMTFDTAAQGKGKDKRLKVTFGPEKGTYGVGQPIVAELNAPVEDRKARAVVENSLKVTSKPAVETGGWYWVDSKTLHYRPKEYWPANATVTARSELGGVRVTDKVRGAAGKPLTIRTGSKIEAVVDASRHAMTVFKDGEELTTLPVTTGKPGFATRNGVKVVLGKEYFVRMRGTSVGIAAGSSESYDLPVYYATRVTWSGEYVHAAPWSVGSHGSANVSHGCVGMSTKNAAWFFETVREGDLVHVVNSIGEDMDPFGNGFGDWNVDWADWKAGSANAPEAPPGKAPGPADRLSPRI
>NC_020990.1|WP_003947649.1|5378048_5378450_-|hypothetical-protein
MQATATVLVYSDNSATREQVRLAAGRRPAADVPPVRFVECATLPAVLKELEHGGIDACVLDGETAPIGGMGVCRQLKDEIFQCPPVLLLMGRPQDAWLATWSRADAAVTLPVEPVEFAGALAALLRPRKPVTA

Crispr_ID: NC_020990_31

• CRISPR_ID: NC_020990_31
• CRISPR_location: 5476780-5476881
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020990_31

Consensus_repeat	Method
CAGCCCGGCCGGCGTTTGAGGCCA	CRISPRCasFinder

spacers of NC_020990_31

>31.1|5476804|54|NC_020990|CRISPRCasFinder
ATCTTTGACCGGCACGGTCACGGTCGGCAGGTTGGGGCGGAGCCCGGCCAAAAC

CRISPR arrays and Neighbor proteins around NC_020990_31

CRISPR arrays

The CRISPR arrays of NC_020990_31

>merge|NC_020990|31|5476780-5476881|CRISPRCasFinder
CAGCCCGGCCGGCGTTTGAGGCCAATCTTTGACCGGCACGGTCACGGTCGGCAGGTTGGGGCGGAGCCCGGCCAAAACCAGCCGGGCCGGCGTTTGAGGCCA

>NC_020990|31|25|5476780-5476881|CRISPRCasFinder
CAGCCCGGCCGGCGTTTGAGGCCA	ATCTTTGACCGGCACGGTCACGGTCGGCAGGTTGGGGCGGAGCCCGGCCAAAAC
CAGCCGGGCCGGCGTTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_010637262.1|5466292_5466877_+|signal-peptidase-II	unknown	unknown	gnl|CDD|237810
NC_020990.1|WP_003947556.1|5484440_5485076_+|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015508029.1|5475399_5476092_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003947561.1|5477123_5480672_+|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl|CDD|235554
NC_020990.1|WP_003947551.1|5489386_5490709_+|histidinol-dehydrogenase	unknown	unknown	gnl|CDD|234853
NC_020990.1|WP_003947554.1|5485625_5486381_-|LON-peptidase-substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|366967
NC_020990.1|WP_003947564.1|5472716_5474363_-|alkaline-phosphatase	unknown	unknown	gnl|CDD|226070
NC_020990.1|WP_003947555.1|5485111_5485606_-|Cys-tRNA(Pro)-deacylase	unknown	unknown	gnl|CDD|237976
NC_020990.1|WP_003947568.1|5467939_5468425_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379326
NC_020990.1|WP_015508028.1|5470924_5472643_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_020990.1|WP_003947552.1|5487588_5489160_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003947563.1|5474489_5475308_-|thioredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|372611
NC_020990.1|WP_003947566.1|5470344_5470914_+|dienelactone-hydrolase	unknown	unknown	gnl|CDD|223489
NC_020990.1|WP_008414086.1|5481171_5482401_+|NYN-domain-containing-protein	unknown	unknown	gnl|CDD|350235
NC_020990.1|WP_003947569.1|5466960_5467905_+|RluA-family-pseudouridine-synthase	unknown	unknown	gnl|CDD|223638
NC_020990.1|WP_015508031.1|5486392_5487430_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_003947557.1|5483491_5484373_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NC_020990.1|WP_008408550.1|5465659_5466121_+|TraR/DksA-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224648
NC_020990.1|WP_008414084.1|5482481_5483495_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_020990.1|WP_003947567.1|5468555_5470142_+|Na+/H+-antiporter	unknown	unknown	gnl|CDD|129911

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_010637262.1|5466292_5466877_+|signal-peptidase-II	gnl|CDD|237810	PRK14764, PRK14764, lipoprotein signal peptidase; Provisional.	1.26533e-89
NC_020990.1|WP_003947557.1|5483491_5484373_+|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	3.11556e-07
NC_020990.1|WP_003947561.1|5477123_5480672_+|DNA-polymerase-III-subunit-alpha	gnl|CDD|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NC_020990.1|WP_003947551.1|5489386_5490709_+|histidinol-dehydrogenase	gnl|CDD|234853	PRK00877, hisD, bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Reviewed.	0
NC_020990.1|WP_003947554.1|5485625_5486381_-|LON-peptidase-substrate-binding-domain-containing-protein	gnl|CDD|366967	pfam02190, LON_substr_bdg, ATP-dependent protease La (LON) substrate-binding domain. This domain has been shown to be part of the PUA superfamily. This domain represents a general protein and polypeptide interaction domain for the ATP-dependent serine peptidase, LON, Peptidase_S16, pfam05362. ATP-dependent Lon proteases are conserved in all living organisms and catalyze rapid turnover of short-lived regulatory proteins and many damaged or denatured proteins.	1.69848e-37
NC_020990.1|WP_003947564.1|5472716_5474363_-|alkaline-phosphatase	gnl|CDD|226070	COG3540, PhoD, Phosphodiesterase/alkaline phosphatase D [Inorganic ion transport and metabolism].	1.07255e-138
NC_020990.1|WP_003947555.1|5485111_5485606_-|Cys-tRNA(Pro)-deacylase	gnl|CDD|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	5.62812e-74
NC_020990.1|WP_003947568.1|5467939_5468425_+|GNAT-family-N-acetyltransferase	gnl|CDD|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.1296e-15
NC_020990.1|WP_015508028.1|5470924_5472643_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.46875e-94
NC_020990.1|WP_003947563.1|5474489_5475308_-|thioredoxin-domain-containing-protein	gnl|CDD|372611	pfam13462, Thioredoxin_4, Thioredoxin.	7.65538e-32
NC_020990.1|WP_003947566.1|5470344_5470914_+|dienelactone-hydrolase	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	1.10159e-24
NC_020990.1|WP_008414086.1|5481171_5482401_+|NYN-domain-containing-protein	gnl|CDD|350235	cd10911, PIN_LabA, PIN domain of Synechococcus elongatus LabA (low-amplitude and bright) and related proteins. This subfamily contains Synechococcus elongatus PCC 7942 LabA which participates in cyanobacterial circadian timing, it is required for negative feedback regulation of the autokinase/autophosphatase KaiC, a central component of the circadian clock system, and appears to be necessary for KaiC-dependent repression of gene expression. This subfamily belongs to the LabA-like domain family which includes the N-terminal domain of limkain b1, a human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes. Also included in the LabA-like domain family are human ZNF451, uncharacterized Bacillus subtilis YqxD, uncharacterized Escherichia coli YaiI, and the N-terminal domain of a well-conserved group of mainly bacterial proteins with no defined function, which contain a C-terminal LabA_like_C domain. Curiously Pseudomonas putida S16 NicB , which is described as a putative NADH-dependent hydroxylase involved in the microbial degradation of nicotine also falls into the LabA-like family. The PIN (PilT N terminus) domain belongs to a large nuclease superfamily. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.79004e-12
NC_020990.1|WP_003947569.1|5466960_5467905_+|RluA-family-pseudouridine-synthase	gnl|CDD|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	2.43857e-103
NC_020990.1|WP_008408550.1|5465659_5466121_+|TraR/DksA-family-transcriptional-regulator	gnl|CDD|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	3.02594e-20
NC_020990.1|WP_008414084.1|5482481_5483495_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.88463e-80
NC_020990.1|WP_003947567.1|5468555_5470142_+|Na+/H+-antiporter	gnl|CDD|129911	TIGR00831, Putative_Na+/H+_exchanger_Rv2287/MT2345/Mb2309., Na+/H+ antiporter, bacterial form. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36) The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria, blue green bacteria, yeast, plants and animals. Transporters from eukaryotes have been functionally characterized, and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in (1) cytoplasmic pH regulation, extruding the H+ generated during metabolism, and (2) salt tolerance (in plants), due to Na+ uptake into vacuoles. This model is specific for the bacterial members of this family. [Transport and binding proteins, Cations and iron carrying compounds].	9.66702e-79

Protein sequences

>NC_020990.1|WP_015508029.1|5475399_5476092_-|hypothetical-protein
MDTPIAETAPRALRAALFTVLAVTLSTTSHVLLSGAPLPLPTVALVGATVFALAWSLAARERSFGRIAALLVPLELAADTVFTAGQHVCYGATGGPVAGPLRTVGVDLLCGGGALGAPLARLLGAPAESPAAFTAHPRPELAWLLLGAHVGVGLLAAAWLRYGERALAQLLRAAAAQAFRPLALAVARVPAPHAPRTARPRPEAAPAGRPALLIAHSVGRRGPPAGLLPA
>NC_020990.1|WP_003947563.1|5474489_5475308_-|thioredoxin-domain-containing-protein
MSKRNSQAAKSAARERLRIEREKQAKKDKARRQLIVAGSVVGVLAIAGGVGFAVVKANEPGYWEKAADQKLVKPANTSGAQGTTVVIGKDDAAKTLKIYEDPRCPVCASFEQNVGETIDQDLKDGKYKLQFVGASFLDRGLGGEGSKNALSALGAALNVSDEAFMAYKSALFSAENHPEESKDEFAKDGKLIEIANQVPELKGNSAFKKDVENGTYDKWALEMSKVFDDNKDGVEGTPSLVMDGKKVTAEGSDNAPQTPEQFNAAVDKALKG
>NC_020990.1|WP_003947564.1|5472716_5474363_-|alkaline-phosphatase
MTSRTEHHPRPAAPSRRTVVLAAAATGALLPLGAATTATAAATPRFLHGVASGDPLPDGVLLWTRVTPTEEAQPGSGAGPDTEVGWEIAADAAFSSVVARGTVTARAATDHTVKADVRGLSPATGYWFRFTAGSTVSPTGRTRTAPAASASPAGLRFGVVSCANWEAGWFSAYRHLAARGDLDAVLHLGDYIYEYATGDYPATPVRPHRPAHEITTLADYRLRHATYKTDPDLAALHARHPVIAIWDDHEFANDAWSGGAENHTPGAEGAWSERSAAARQAYFEWMPVRASTEGTVFRRLRFGDLADLHLLDLRSFRSEQVSIGNGAVDSPDRSITGRAQLDWLKAGLSGSQAAWQLVGTSVMISPVAFGSVPAHLLKPLAELLGLPTQGLAINVDQWDGYTADRTELIRHLRSAGIRDTVFLTGDIHMAWANDVPVTAATYPLSESAATEFVVTSVTSDNLDDLLKVAPGTLSTVAEGAIKAANRHVKWLDMDGHGFGVLDVTAERSQMDYYLLSDRADPGATASWLRSYRTRRGTQRVERADAPVA
>NC_020990.1|WP_015508028.1|5470924_5472643_-|serine/threonine-protein-kinase
MFRQGAVTARRRLDTLGPMSAPGEMIGGRFTLLAPLGSGGMGTVWRARDEVLHREVALKEVRPPDPAMTGPEAAATLRERVLREARALARLSHPHVVTIHQIVDAGAGTHPWIVMELVPGESLADRLQRGPLLPQEAATLGRQLLAALRSAHAAGIHHRDVKPANILLRTDPGVPGPPSAILTDFGIAALQGSTALTATGDLIGSPEYIAPERVRGRDDHPASDLWSLGLVLYVAVEGHSPLRRATTLATLAAVLDEPVPPPVRSGPLAAVLGALLVRDPEARPDAATLDRLLTEAASGSAPSWAEPTVSGPGPVPAAPVTPPPPGPPTPPPGAPAAGTPAPAPYRPPLPTPTTAVARPRRRTGALVAGAAALVAVAVTATVLVLNPWKSDNHAAPSPSPSPTATRSPDGEKDPKPSPDTGSTGTDPVDEDKNGDGEEDQEKEDDRPGQDDSPSPSATPQPPSGGSWIAQLFSEPVSTGTATRDRRLAAVRAEVPEARYLRSDDYASLRPGYWVFYVPGPFDDGRAALRFCAEKGRTSGNECVGRYLSDDGSDADAICHPPAASPKGRCTRS
>NC_020990.1|WP_003947566.1|5470344_5470914_+|dienelactone-hydrolase
MEILLIHSVYGVRPALEQAAERLREAGHEVHVPDLFEGLSPADMEEGLALRDEIGTDELLKRAVRAAAPYSDKGLVYAGFSLGGAIAQNLALADEKARGLVLFSGTSDLPDDASAEDLPVQLHVTENDPFEPHDWLNAWYLRMQRAGADVEVYRYPGAGHLYTDPELPDYDAEAAEATWRTVQGFLDSL
>NC_020990.1|WP_003947567.1|5468555_5470142_+|Na+/H+-antiporter
MDQLALLLLLLLGAVITVPLGDRLGLPAPVLMTLGGIVLALLPFVPNVNVPPEYILPLVLPPLLYAAVQRTSWRQFTANYRPILLLAVALVFVTTAAVAGVANAIVPGLPLAAAVALGALVAPPDPVAATAVAGQLGLPRRLVSVLEGEGLFNDVTAIVLYHVAIAAAVTGTFSWGGAVGQFFLSAAVAVAVGLALGWVSKKMMSMLGDATLQTGLTLLVPFASYILAEELHGSGVLAVLTTALLLAGTALDADDVLGRITGQTFWHVVDTLVTGIAFGLIGLELHTVIRAAEGREGQMIGWGVAIVAVVVGVRLLWLLPTTWLAQKMHSLRDENEEIPTSWRETVVMWWSGMRGVASVALALAIPLTTDDGKPFPARDEIIFIAFCVIMATLLVQGLTLPWLVRKLGVTADTDAEHKLEHDLAIRAAKAARRRLKEIEATEELPEDISERLQRGALDIGVRISPDLLDDERREWWVQRAERVAAMSRVQREMMSAARREVLSARNEPGADPEVVDRVLRQLDVRSLR
>NC_020990.1|WP_003947568.1|5467939_5468425_+|GNAT-family-N-acetyltransferase
MSQPTPADVRVRVAEGPADREACFAVRKEVFVAEQGVDEAIEYDAFDAPESDTVHVLAEGPDGPLGTGRLLHGPAAAGATGGEPGVGSLGRLAVRQAARGLGVGAALVRGLEGAAAQLGLRAVDLHAQTHALGFYERLGYQAYGPEFEDAGIGHRAMRREL
>NC_020990.1|WP_003947569.1|5466960_5467905_+|RluA-family-pseudouridine-synthase
MSTIPEIRTLPVPDGLEGERVDAAISRMFGFSRTKAAELAAAGKVLVDGAAVGKSERVHGGAWLEVEMPAAPAPVQIVAEPVEGMEIVHDDDDIVVIVKPVGVAAHPSPGWTGTTVIGGLAAAGYRISTSGAAERQGIVHRLDVGTSGLMVVAKSERAYTLLKQQFRERTVDKRYHALVQGHPDPMSGTIDAPIGRHPQHDYKWAVTAEGKPSVTHYDLIEAYRAASLLDIKLETGRTHQIRVHMSAHRHPCVGDLTYGADPTLAKRLGLTRQWLHAVRLGFEHPADGSWAEFSSEYPADLQHALDTVRAESNA
>NC_020990.1|WP_010637262.1|5466292_5466877_+|signal-peptidase-II
MPETPEAREPDRAEPPEPGGDEQEGGATAAAPRGPRRVAVLFTVAVVAYLLDLGSKLLVVAKLEHHAPIQVLGDWFELRVIRNAGAAFGFGEAFTIIFTVIAASVIVVIARLARKLYSLPWALALGLLLGGALGNLTDRIFRAPGVLEGAVVDFLAPKNFAVFNLADSAIVCGGILIVILSFRGLDPDGTVHKD
>NC_020990.1|WP_008408550.1|5465659_5466121_+|TraR/DksA-family-transcriptional-regulator
MVAKKTGTAEKSGPVPQARAGAEALAVRPGEDPWTEAEAEEARAGLRADAERIRTEIDASGQALAGLMRDSGGGAGDDEADTGTKNITREHELSLAANAREMLRQTEQALVRLDEGTYGTCENCGNPIGKARLQAFPRATLCVDCKQKQERRG
>NC_020990.1|WP_003947561.1|5477123_5480672_+|DNA-polymerase-III-subunit-alpha
MSATSKPPFTHLHVHTQYSLLDGAARLKDMFDACNEMGMTHIAMSDHGNLHGAYDFFHSAEKAGVTPIIGIEAYVAPESRRTKRKIQWGQPHQKRDDVSGSGGYTHKTIWAANSTGLHNLFRLSSDAYSEGWLQKWPRMDKESISQWSEGLIASTGCPSGEVQTRLRLGQEEEALRAAAEYQEIFGKDRYFLELMDHGIEIERRVRQGLLDIGKKLGIPPLVTNDSHYTYSHESVAHDALLCIQTGKNLSDPDRFRFDGTGYYLKSTEEMYAIDSSDAWQEGCRNTLLVAEQIDTTGMFEKRDLMPKFDIPDGFTEVTWFQEEVRRGMARRFPAGVPEDRQRQAEYEMDVIIQMGFPGYFLVVADFIMWAKNNGIAVGPGRGSAAGSIVAYAMGITDLDPIEHGLIFERFLNPERVSMPDVDIDFDERRRVEVIRYVTEKYGADKVAMIGTYGKIKAKNAIKDSARVLGYPYAMGDRLTKAMPADVLGKGIDLDGITNPKHPRYSEAGEIRGMYENEPDVKKVIDTAKGVEGLVRQMGVHAAGVIMSSEPIVDHAPLWTRHTDGVTITQWDYPQCESLGLLKMDFLGLRNLTIMDDARKMVEANKGIDLDLLALPLDDPKTFELLCRGDTLGVFQFDGGPMRSLLRLMKPDNFEDISAVSALYRPGPMGMNSHTNYALRKNGQQEITPIHPELEEPLKEILGLTYGLIVYQEQVQKAAQIIAGYSLGEADILRRVMGKKKPEELAKNFVLFQEGAKKKGFSDEAIQALWDVLVPFAGYAFNKAHSSAYGLVTYWTAYLKANYPAEYMAALLTSVKDDKDKSAVYLNECRRMKIKVLPPDVNESVHNFAAQSDDVILFGLEAVRNVGTNVVESIIRARKAKGKFSSFPDYLDKIEAQACNKRTTESLIKAGAFDALGHTRKGLTAHYEPMIDNVVAVKRKEAEGQFDLFGGMGDDNADEPGFGLDIEFTDEEWDKTYLLAQEREMLGLYVSDHPLFGLEHVLSDKADAGIGQLTGGDFGDGAVVTVGGIISGLQRKMTKQGNAWAIATVEDLAGSIECMFFPATYQLVSTQLVEDAVVFVKGRLDKREDIPRLVAMELQVPDLSNAGTNAPVIITIPAVKVTPPMVSRLGEVLDSHRGNSEVRIKLQGPRKTTVLRLDRHRVQPDPSLFGDLKVLLGASCLAG
>NC_020990.1|WP_008414086.1|5481171_5482401_+|NYN-domain-containing-protein
MDRCVVLVDAGYLLGAAASLLAGDPSRSRISVDHATLVRQLRERAEAETAQPLLRIYWFDGAPDRVPQPEHRRLRVMPRVTVRLGALTRSDGRWAQKGVDAAMHAELTELARNKACSDIVLVTGDGDLLPGMTAAKEHGVAVHLWAVQAAGGDYNQSEDLVAEADERRLLDRAWITRAIRARDTAGPCAPQPAPGPEIAAILSAPLPDTAARPARDPEPEHTPAPAETNGTGAGAARAVPTPKDLAALRAADRPAPVKEQPATATLRWSSDKGLVERQGPADSPDDAALPTLAHLTTAEQRWADREEDITTVGGDPFEVGQVFARRWLSRLGDRTLLPRLAALYPRIPHRIDGELLRYAARFGLLAHKDDQIDEHDRYAIRAGFWREIDLPATGQPTAGQPLQPARPLT
>NC_020990.1|WP_008414084.1|5482481_5483495_+|ABC-transporter-ATP-binding-protein
MDRTDPAPAPEGEAVCVVRDLVKTYPATRGRRGAPAVPEVRATDHIDLDVRGGEIFGLLGPNGAGKSTLVRQLTGLMRPDSGSVRLLGHDVVRHPERAARLLAYLGQESTALDELTVSLAAETTARLRGLDAPAARAQRDAVLDELGLGPLASRPLKKLSGGQRRLACFATALVGRRPLLVLDEPTTGMDPVARRAVWAAVDRRRAEEGTTVLLVTHNVIEAETVLDRVAVLEQGRVIACDTPSGLKAHVAHEVRLDLLWRERPPLDVPEVAALRDSAAESGRRWVLRLAPDEARAAVAAVTGGSAFAALDDFTLATPSLEDVYLALGGSGTGLVKT
>NC_020990.1|WP_003947557.1|5483491_5484373_+|ABC-transporter-permease
MTGGPATPTTDRRAPAPGRAAHGTGPGMSTTARTAAPRAVAAPAALAPRARLLPALAAVYRAQLSRARVARIPLLFVATFQSVGIMILMRGVVDGGTEAHAVVAGSSVLVVAFVALNLLAQYFGQLRAGGGLDHYATLPVPPAAVVLGAAGAYASFTVPGTLVTALVGCVLFQLPLAQLWVLIAVIPLAGAALSGLGAALGLLAPRPELATLLGQLGMSAALLLGVLPPERLPALLVLARDLLPSTYGVEAFARTFAPHPDWAAVLVDLGVCAGVGVVSLTLATWAYRRAAVR
>NC_020990.1|WP_003947556.1|5484440_5485076_+|hypothetical-protein
MTAPLNPPPPPHGRPGYDPWQLPEGAHPDHPRGTERDEPLGREIRRAALTGLAVVALGLLLGFLWSRLAPHVPLVSDGEAVYLKDTEGEQAIGADGTFALLALGFGAVTGLAAFLVHRAGGIAMVCGLALGSLGGAAVAWQLGMALGPSGDVVGHARTAGQGVTFDAPLELGALGVLVAWPIAALLVHLGLTALFGPREEPRAHHWQTYEG
>NC_020990.1|WP_003947555.1|5485111_5485606_-|Cys-tRNA(Pro)-deacylase
MAKKQKKQSGGTPATVALTAAGAAFTTHAYEHDPAHPSYGEEAAEAMGVSPDRVFKTLVAEVDGRLTVAVVPVSGSLDLKALATAAGGKKAAMADPAAAERTTGYVRGGISPLGQRKALPTVLDASATGHATICVSAGRRGLEVELAPAVLAELTGAVTAPIAR
>NC_020990.1|WP_003947554.1|5485625_5486381_-|LON-peptidase-substrate-binding-domain-containing-protein
MTTVRLPLFPLNTVLFPGLVLPLNVFEARYRAMMRDLLDSLPEDPESDEPCQFVVVAIRDGHEVAPSEPGMPDDAGRPEAGPMTGFGDDPARSLHAVGCVADAATIREREDGGYEVLATGTTRVRLHSIDTSGPYLTAEAEELPEDPGDEAGALAEGVLRAFRSYQKRLAGARELTLTSNADLPDEPSVVSYLVAAATVLDVPTRQRLLQAPDTASRLRDELALLRRETAVIRHLPSLPAAELTRTPTSLN
>NC_020990.1|WP_015508031.1|5486392_5487430_-|hypothetical-protein
MVGTMALLQALIRTARMVTHTTRLATGLPPDEEVYLDLPDDRLAPALAAAGLGDHRPAAEVLAASREAAAWETRDRQVQRLAAFARNRPEWFDAWSYAAPHDPDVALIRAELAVRRGWESPARAELLHDVTPLIAAAARAEPADPVPWRIALDHARGTGAPHTEFEARWEQAVRRSSYHYGCHVAALQYLSAAWFGSHRESFAFAERAAEDALPGSLVRGLPVRAAFGALHRGPDAPGRGGPVLRERLDAAADTAIALSAEYPAGDPWPAEVRNVLLYVLIRLERWADALEQARLIGTRATSFPWDRISDDPLGQFLQARDGVRIEVAASLPLRGTRRREKAGDH
>NC_020990.1|WP_003947552.1|5487588_5489160_-|hypothetical-protein
MSTEQGGEPPEGLTATEYGMWQAFRNGSTYDLRAGEAALDDPHGGLPWGEERSVRARVVSLLLLHGPDPLPGRVSSLKLAGVQITDVLDLAGGTVEPYVELIGCRFEKEVLLPEARFTTLRLVDCSLPRLEAARVSTEGDLHLPRCRVHRGVRLTDAQIGTDLLLNQAVVHRDRRGTSLLGDGLSVGQDFQAEMMEAHGEVSLRGAQIGVSLSLRGSRLANPYGRRALNAPQLTVGRTLYLTPAGVGNPALTSGTTPARGTRVQRFECRGGVRLDDGRVGDAVDLDQARFVMEEYQELSLRRVQTPELRFLCERPAQGRVVLSGAKVGNLMDQTPSWPGPGGLAMGGFTYDNLVPRGRFTLAERLTWVEAATPEYNPEPYELLAAVLRASGEDADAREVLLAKQRRRRETLGLAGTVWGYLQDWTVAYGYRPGRAALWMAVLWAVSALLFAQIDPAPIKDDEHPPWSSSLFTLDLLLPVIDLGQTGYWHLDGGWQWVTALLILLGWILATTVAAGATRLLRRG
>NC_020990.1|WP_003947551.1|5489386_5490709_+|histidinol-dehydrogenase
MISRIDLRGEALPEGPALRALLPRADFDVTAALEKVRPICEDVHHRGDAALIEYARRFDQVTLEQVRVPAEALAEALAGLTDEVRAALEESIRRARTVHRAQRRTPHTTQVVPGGTVTEKWVPVDRVGLYAPGGRSVYPSSVIMNAVPAQEAGVPSIALASPPQAEFGGLPHPTILAACALLGIDEVYAVGGATAVAMFAYGTESCPPARMVTGPGNIWVAAAKRYFTGLIGIDTEAGPTEIAVLADDTADPVHVAADLISQAEHDPLAAAVLVTDSDALADAVEKELAVQVPATRHVEDRIAPALAGRQSALVLVADLEDGLKVVDAYGAEHLEIQTADATAVADRVRNAGAVFVGPWAPVSLGDYCAGSNHVLPTGGCACHSSGLSVQSFLRGIHIVDYSRDALADVAHHVVTLAEAEDLPAHGAAVKARFDWKVPQQ

Crispr_ID: NC_020990_32

• CRISPR_ID: NC_020990_32
• CRISPR_location: 6127640-6127912
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NC_020990_32

Consensus_repeat	Method
GGCCTCAAGCGCCGGCCGGGCTG	CRISPRCasFinder

spacers of NC_020990_32

>32.1|6127663|54|NC_020990|CRISPRCasFinder
TTCTGCCGGGCTCCGTCGCGGCGTCCCGGACCGTGACCGTGCCGGTCACCGATC
>32.2|6127740|53|NC_020990|CRISPRCasFinder
TTTTCTGCCGGGCTCCGCCCCTGACCTGCGGGGATCGGCCGGTCGCCCGTGGT
>32.3|6127816|25|NC_020990|CRISPRCasFinder
ATCGTCCTCATGCCGGACGGGCCGT
>32.4|6127864|26|NC_020990|CRISPRCasFinder
GGAGTGTCGGGTGGTCTGGGAAGGGC

CRISPR arrays and Neighbor proteins around NC_020990_32

CRISPR arrays

The CRISPR arrays of NC_020990_32

>merge|NC_020990|32|6127640-6127912|CRISPRCasFinder
GGGGTCGGGCCCCTGGCGGGCTGTTCTGCCGGGCTCCGTCGCGGCGTCCCGGACCGTGACCGTGCCGGTCACCGATCGGCCTCAAGCGCCGGCCGGGCTGTTTTCTGCCGGGCTCCGCCCCTGACCTGCGGGGATCGGCCGGTCGCCCGTGGTGGCCTCAAGCGCCGGCCGGGCTGATCGTCCTCATGCCGGACGGGCCGTGTCCTCAAGCGCCGGACGGGCTCGGAGTGTCGGGTGGTCTGGGAAGGGCGTCCACAAACGCCGGACGGGCTG

>NC_020990|32|26|6127640-6127912|CRISPRCasFinder
GGGGTCGGGCCCCTGGCGGGCTG	TTCTGCCGGGCTCCGTCGCGGCGTCCCGGACCGTGACCGTGCCGGTCACCGATC
GGCCTCAAGCGCCGGCCGGGCTG	TTTTCTGCCGGGCTCCGCCCCTGACCTGCGGGGATCGGCCGGTCGCCCGTGGT
GGCCTCAAGCGCCGGCCGGGCTG	ATCGTCCTCATGCCGGACGGGCCGT
GTCCTCAAGCGCCGGACGGGCTC	GGAGTGTCGGGTGGTCTGGGAAGGGC
GTCCACAAACGCCGGACGGGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020990.1|WP_003946980.1|6118728_6120597_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|188437
NC_020990.1|WP_003946981.1|6118223_6118691_+|PH-domain-containing-protein	unknown	unknown	gnl|CDD|371225
NC_020990.1|WP_003946977.1|6123364_6124624_-|glycoside-hydrolase-family-18-protein	unknown	unknown	gnl|CDD|119365
NC_020990.1|WP_008407389.1|6127184_6127625_+|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|214628
NC_020990.1|WP_015508182.1|6121047_6121671_-|hypothetical-protein	unknown	unknown	gnl|CDD|235825
NC_020990.1|WP_003946974.1|6126492_6126921_-|hypothetical-protein	unknown	unknown	unknown
NC_020990.1|WP_015508183.1|6124989_6126162_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NC_020990.1|WP_003946970.1|6131052_6131625_+|FxsA-family-protein	unknown	unknown	gnl|CDD|377238
NC_020990.1|WP_003946983.1|6116989_6117262_+|phosphoribosyl-ATP-diphosphatase	unknown	unknown	gnl|CDD|212154
NC_020990.1|WP_010636502.1|6135277_6136804_+|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NC_020990.1|WP_003946964.1|6136859_6138434_-|hypothetical-protein	unknown	unknown	gnl|CDD|369998
NC_020990.1|WP_003946972.1|6128019_6129672_+|amidohydrolase	unknown	unknown	gnl|CDD|224490
NC_020990.1|WP_003946968.1|6132357_6133710_-|MFS-transporter	unknown	unknown	gnl|CDD|341035
NC_020990.1|WP_003946969.1|6131728_6132103_-|RNA-polymerase-binding-protein-RbpA	unknown	unknown	gnl|CDD|379162
NC_020990.1|WP_015508184.1|6133745_6134504_-|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl|CDD|176504
NC_020990.1|WP_015508185.1|6134518_6135178_-|membrane-protein	unknown	unknown	gnl|CDD|225239
NC_020990.1|WP_003946971.1|6130200_6130989_+|polyprenol-monophosphomannose-synthase	unknown	unknown	gnl|CDD|133062
NC_020990.1|WP_003946978.1|6121931_6123293_+|peptidase-C39-family-protein	unknown	unknown	gnl|CDD|239109
NC_020990.1|WP_003946982.1|6117333_6118191_+|ATP-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234781
NC_020990.1|WP_003946963.1|6138465_6138660_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020990.1|WP_003946980.1|6118728_6120597_-|AAA-family-ATPase	gnl|CDD|188437	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA. This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking].	7.68137e-85
NC_020990.1|WP_003946981.1|6118223_6118691_+|PH-domain-containing-protein	gnl|CDD|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	1.93863e-12
NC_020990.1|WP_003946977.1|6123364_6124624_-|glycoside-hydrolase-family-18-protein	gnl|CDD|119365	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.	5.17812e-113
NC_020990.1|WP_008407389.1|6127184_6127625_+|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	4.87597e-43
NC_020990.1|WP_015508182.1|6121047_6121671_-|hypothetical-protein	gnl|CDD|235825	PRK06547, PRK06547, hypothetical protein; Provisional.	5.68424e-16
NC_020990.1|WP_015508183.1|6124989_6126162_+|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
NC_020990.1|WP_003946970.1|6131052_6131625_+|FxsA-family-protein	gnl|CDD|377238	pfam04186, FxsA, FxsA cytoplasmic membrane protein. This is a bacterial family of cytoplasmic membrane proteins. It includes two transmembrane regions. The molecular function of FxsA is unknown, but in Escherichia coli its over-expression has been shown to alleviate the exclusion of phage T7 in those cells with an F plasmid.	4.38844e-27
NC_020990.1|WP_003946983.1|6116989_6117262_+|phosphoribosyl-ATP-diphosphatase	gnl|CDD|212154	cd11547, NTP-PPase_HisE, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Mycobacterium tuberculosis phosphoribosyl-ATP pyrophosphohydrolase (HisE or PRATP-PH) and its bacterial homologs. This family includes M. tuberculosis phosphoribosyl-ATP pyrophosphohydrolase (HisE or PRATP-PH) and its bacterial homologs. M. tuberculosis HisE is encoded by the hisE gene, which is a separate gene presenting in many bacteria and archaea but is fused to hisI in other bacteria, fungi and plants. HisE is responsible for the second step in the histidine-biosynthetic pathway. It can irreversibly hydrolyze phosphoribosyl-ATP (PRATP) to phosphoribosyl-AMP (PRAMP) and pyrophosphate. HisE dimerizes into a four alpha-helix bundle, forming two inferred PRATP active sites on the outer faces. M. tuberculosis HisE has been found to be essential for growth in vitro, thus making it a potential drug target for tuberculosis.	7.11811e-43
NC_020990.1|WP_010636502.1|6135277_6136804_+|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.10466e-86
NC_020990.1|WP_003946964.1|6136859_6138434_-|hypothetical-protein	gnl|CDD|369998	pfam08611, DUF1774, Fungal protein of unknown function (DUF1774). This is a fungal family of unknown function.	0.00118185
NC_020990.1|WP_003946972.1|6128019_6129672_+|amidohydrolase	gnl|CDD|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	2.20768e-105
NC_020990.1|WP_003946968.1|6132357_6133710_-|MFS-transporter	gnl|CDD|341035	cd17482, MFS_YxiO_like, Bacillus subtilis YxiO, Listeria monocytogenes BtlA, and similar transporters of the Major Facilitator Superfamily. This family is composed of Bacillus subtilis MFS-type transporter YxiO, and similar proteins including Listeria monocytogenes BtlA. The function of B. subtilis YxiO is still unknown, and L. monocytogenes BtlA is a putative secondary transporter involved in bile tolerance and general stress resistance. This family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.4651e-140
NC_020990.1|WP_003946969.1|6131728_6132103_-|RNA-polymerase-binding-protein-RbpA	gnl|CDD|379162	pfam13397, RbpA, RNA polymerase-binding protein. RbpA is a family bacterial RNA polymerase-binding proteins. RbpA acts as a transcription factor by binding to the sigma subunit of RNA polymerase.	2.50612e-51
NC_020990.1|WP_015508184.1|6133745_6134504_-|glycerophosphodiester-phosphodiesterase	gnl|CDD|176504	cd08561, GDPD_cytoplasmic_ScUgpQ2_like, Glycerophosphodiester phosphodiesterase domain of Streptomyces coelicolor cytoplasmic phosphodiesterases UgpQ2 and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in a group of uncharacterized cytoplasmic phosphodiesterases which predominantly exist in bacteria. The prototype of this family is a putative cytoplasmic phosphodiesterase encoded by gene ulpQ2 (SCO1419) in the Streptomyces coelicolor genome. It is distantly related to the Escherichia coli cytoplasmic phosphodiesterases UgpQ that catalyzes the hydrolysis of glycerophosphodiesters at the inner side of the cytoplasmic membrane to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	2.23929e-89
NC_020990.1|WP_015508185.1|6134518_6135178_-|membrane-protein	gnl|CDD|225239	COG2364, COG2364, Predicted membrane protein [Function unknown].	4.52113e-42
NC_020990.1|WP_003946971.1|6130200_6130989_+|polyprenol-monophosphomannose-synthase	gnl|CDD|133062	cd06442, DPM1_like, DPM1_like represents putative enzymes similar to eukaryotic DPM1. Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily.	5.4918e-98
NC_020990.1|WP_003946978.1|6121931_6123293_+|peptidase-C39-family-protein	gnl|CDD|239109	cd02549, Peptidase_C39A, A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic). The cleavage is mediated by the transporter as part of the secretion process. Bacteriocins are antibiotic proteins secreted by some species of bacteria that inhibit the growth of other bacterial species. The bacteriocin is synthesized as a precursor with an N-terminal leader peptide, and processing involves removal of the leader peptide by cleavage at a Gly-Gly bond, followed by translocation of the mature bacteriocin across the cytoplasmic membrane. Most endopeptidases of family C39 are N-terminal domains in larger proteins (ABC transporters) that serve both functions. The proposed protease active site is conserved in this sub-family of proteins with a single peptidase domain, which are lacking the nucleotide-binding transporter signature or have different domain architectures.	6.01536e-29
NC_020990.1|WP_003946982.1|6117333_6118191_+|ATP-phosphoribosyltransferase	gnl|CDD|234781	PRK00489, hisG, ATP phosphoribosyltransferase; Reviewed.	2.37437e-139

Protein sequences

>NC_020990.1|WP_008407389.1|6127184_6127625_+|Lrp/AsnC-family-transcriptional-regulator
MEDLDRQIVQLLVADGRMSYTDLGKATGLSTSAVHQRVRRLEQRGVIRGYAAVVDPEAVGLPLTAFISVKPFDPSAPDDIAERLAGVPEIEACHSVAGDENYILKVRVTAPVALEDLLSRVRSLAGVSTRTTVVLSTPYEARPPQL
>NC_020990.1|WP_003946974.1|6126492_6126921_-|hypothetical-protein
MQSAKRSHRAARSRQQPAVELVPDPVEESEEELDAYETFGMFRVVCPDCAQPIALLADEETLPQHALCATPWDPFGLTVCSGTGRPAGEALPAGEETGRHAQDAAVLLTLPQTLDWRTQPFSHVGGPGSRPIGLQRVRGQAA
>NC_020990.1|WP_015508183.1|6124989_6126162_+|acyl-CoA-dehydrogenase
MNDRAPQAVDRQLPTEEARDLISLVREMVRRDIAPATAEEEEAGRFPRETFTRLSESGLLGLPYPVEYGGGDQPYEVYLQVLEELAAARLTVGLGVSVHTLACHALVAFGTDEQRAAHLPAMTGGGLLGAYGLSEPAAGSDAASLRTRARRDGDDWVIDGSKAWITHGGIADFYTVMARTGEDGPRGITAFLVPGDAPGLSAAAPERKMGMKGSPTAQIHLDGVRVGDDRRLGDEGQGFAVALAALDSGRLGIAACATGVAQAALDAALEYASGRRQFGRPIADFQGLRFLLADMATQVEAGRALYLAAARLRDAGLPFSRQAAMAKLFCTDAAMKVTTDAVQVLGGYGYTADFPVERLMREAKVLQIVEGTNQIQRMVIARHLAGPESR
>NC_020990.1|WP_003946977.1|6123364_6124624_-|glycoside-hydrolase-family-18-protein
MPRTRSRSRLTALLAAATSAVLGAGLLAGAATASAEPAPSPTTGAQAEAGAQAGSKVIGYFTEWGVYDRNYHVKNIETSGSADKLTHINYSFGNVQGGKCALGDGFAATEKAYTAEESVDGEADAWDQPLRGNFNQLLKLKELHPDLKVLWSFGGWTWSGGFTEAAKDPAAFARSCHDLVEDPRWAEVFDGIDVDWEYPNACGLTCDESGPEAFGEVVSALRAEFGEEYLVTAAIPADASEGGKLDATDYAGAAQYVDWYNPMTYDYYGAWDAEGPTAPHSPLTAYDSIPDASFTTEATIAKLKEAGVPASKLLLGLGFYGRGWTGVTEEAPGGSASGPASGVYEQGIEDYKVLKERCPATGEAGGTAYALCGGEWWSYDTPATIAGKMTFKEREGLAGTFFWELSGDTADGELIRAID
>NC_020990.1|WP_003946978.1|6121931_6123293_+|peptidase-C39-family-protein
MTRSELPRRALLTAAAAVAATAAAGPAAASGALPRPSAAGRQEPATIDNHFWSTASDWLQGRASGIRVVAGSRPGIRIAAPAGVAEYTDPHTGTTAAWEYATWTSPLHRSKVPATELIASWNARTPAGTWLQIEAEGVYADGARTPWYVLGRWASGDQDIRRTSVDDQGDDRTSVWTDTVSVDDAASGTRIVAYRLRLTLYRTPGSGATPVVWRAGAMTSDIPDRFTVPATSPGRARELAVPRYSQNTHVGQYPEYDNGGEAWCSPTSSQMIIEYWGRRPTAEDLAWVNPDYDDPQVCHAARFTYDYQYEGCGNWPFNAAYAATYDDLRAVVTRLGSLSDLHRLVSAGIPVITSQSFLAEELTGAGYGTSGHLMTVIGFTEAGDIIANDPASPSNEAVRRVYDRTEWSNIWLRTKRYAADGRVLSGTGGVCYLYFPADASAAQRAALASVGIR
>NC_020990.1|WP_015508182.1|6121047_6121671_-|hypothetical-protein
MRQDPLGSPGPLPRLAAEVRAARPSLGPVRLIAVDGHAGSGKTTFAGQLAGALGGAPVLHLDDLATHEEPFAWTARLREQVLAPLGRGEEARYRPYDWHRRAFGPPRPLPAAPVVLLEGVGAGRRAVRPVLARLLWMEVDARTAHGRGQARDGAEQAAFWRGWVPAERRHFASDPSRPFADTLVRPGAAGPALLSGPGRDGRQPPSP
>NC_020990.1|WP_003946980.1|6118728_6120597_-|AAA-family-ATPase
MDFGTQGSRAPADLAWLRGVDAYTMGAYPQAEEEFREAVRLDPRMADGWLGLHALRIDTTTALLHMYEHRDRFGEQRARHRRTLNSWYWLGWWVQPVLESSRDLLLAHASHWLDGRHVPELDRALAGLPPVEADAQVRFLHACRAYLVKDWEQLVRHTDPLRDDPLLGIEAGLFGGMARVRLEMFGHAEPLLSAALMRCRSEQPQRKELRYWLARAHEGTGRSAAALPLYRAVHRVDPAFMDTAARLAAITEGDGYADLADAVDLSTVAVAQNVEAPEQAEPGYGTDPGGRELRTEAVPDPVAVPVPPDAAREKAASARRPGGWLPTGSADPVALEQALAELERMVGLEPVKRQVKALSAQLNMARLRAGQGLPVRPPKRHFVFSGPSGTGKTTVARILGRVFYALGLLGGDHLVEAQRSDLVGEYLGQTAVKANELIDSALGGVLFVDEAYSLSNSAYGRGDAYGDEALQVLLKRAEDNRDRLVVILAGYPEGMDQLLTANPGLGSRFTTRVDFPSYRPAELTAIGGVLAAENGDGWDEEALEELRSISGHVVEQGWIDELGNGRFLRTLYEKSCAYRDLRLTAFPHTPGREDLATLRLPDLMQAYGEVLSGRGPQNPPAL
>NC_020990.1|WP_003946981.1|6118223_6118691_+|PH-domain-containing-protein
MSTEHGTPELPPLPVDFRPAKTRAVLLAAAVAIFVVVSAVALLLDSLSPAEKTSFVFTAALLAGILVLLARPRVRADEDGVTVVNITRVRRLAWAEIVRVNLRTGDAWVFLDLSDGTSMPVLGIQPGNGRAAAVRDARLLRALAERHSSELPSGG
>NC_020990.1|WP_003946982.1|6117333_6118191_+|ATP-phosphoribosyltransferase
MLRIAVPNKGSLSGPASAILHEAGYQQRKESKELVLVDPVNEVEFFYLRPRDIAIYVATGRLDIGITGRDLLVDSGADAEEILPLGFARSTFRFAARPGTAESADDLKGRTVATSYEGIVARHLAEHGVDASVVHLDGAVETAIELGVAQVIADVVETGTSLRNAGLEVFGEPIMHSEAVVIRRTGAGSEDAAEPKVQQFLRRIQGVLVARAYVMMDYDCRAEHLEQAVALTPGLESPTVSPLHNEGWVAVRAMVPAKDAQRIMDDLYALGARAILTTAIHACRL
>NC_020990.1|WP_003946983.1|6116989_6117262_+|phosphoribosyl-ATP-diphosphatase
MSKKTFEELFTELQQKAAHGDPTTSRTAELVDKGVHAIGKKVVEEAAEVWMAAEYEGKEAAAEEISQLLYHVQVMMVARGISLDDVYAHL
>NC_020990.1|WP_003946972.1|6128019_6129672_+|amidohydrolase
MSDSTAPPRTEPSATRTVLLRGGEVHSPADPFATAMVVERGQVAWVGSEGAADAFADGVDEVVHLDGALVTPAFTDAHVHLTSTGLARTGLDLSGTRTVEQALDLVRAHAEARPHDRVLLGHGWDAARWPGQFPPGRAQLDEASGGRPLYLSRIDVHSAVVSTALLDLVPGVTERAGYRPDAPLTGDAHHAVRAAALGAVTPAQRAEAQRAALREAASLGVGSLHECAGPEISSEDDFTGLLRLAAEEAGPRVTGYWGELVTGPEGIDRIRDLGAHGAAGDLFVDGALGSHTACLHAPYEDAGHTGTAHLDAAAVAAHVVACTEAGLQAGFHAIGDAALTAVVEGVRAAAEKAGLARIRAARHRVEHAEMLTDETLAALAELGITASVQPVFDALWGGEDGMYAQRLGTERARTLNPFAAMLRAGIPLAFGSDSPVTPVAPWEAVRAAAFHRTPEHRVSVRAAFTAHTRGGWRAIGRDDAGVLVPGAPADYALWRTEELLVQAPDDRVARWSTDPRSGTPGLPDLTPGAELPVCLETVVGGETVYVRPPE
>NC_020990.1|WP_003946971.1|6130200_6130989_+|polyprenol-monophosphomannose-synthase
MNDGGDRASAAPREEYGPLGTTLVIIPTYNEADNLAPVVARVRAAVPEAHVLVADDNSPDGTGKIADELAADDEQVHVLHRAGKEGLGAAYLAGFRWGLEREYGVLVEMDADGSHQPEELPRLLTALKGADLVLGSRWVPGGRVVNWPRGRQLLSRGGSTYSRLLLDVPLRDITGGYRAFRRETLEKLGLTEVASQGYCFQVDLARRAVQSGCTVVEVPITFVEREHGDSKMSRDIVVEALWRVTAWGVGGRVSKALGRTPG
>NC_020990.1|WP_003946970.1|6131052_6131625_+|FxsA-family-protein
MTTGAPPPSRNAPRSRLRTFLPLALVAWLILEVWLLTRVAEATSGFIVFLLLLAGVVAGSAQIKRAGRRALRKFQETVAQQQGITPETDRSGGNAFLLIAGLLLILPGLISDVFGLVLLLPPVRTALARRAERSLERRMAAAGPGTFGGAFQQARMRAPDGKVVQGEVVRDDEPPRPEGRDDDPRPPLTP
>NC_020990.1|WP_003946969.1|6131728_6132103_-|RNA-polymerase-binding-protein-RbpA
MSERALRGTRLVVTSYETDRGIDLAPRQAVEYACQNGHRFEMPFSVEAEIPPEWECKVCGAQALLVDGDGPEEKKGKPARTHWDMLMERRTREELEEVLAERLAVLRSGAMNIAVHPRDSRKSA
>NC_020990.1|WP_003946968.1|6132357_6133710_-|MFS-transporter
MSSGTVPAEESGRAAARRREQRGWYVYDWACSVYSTSVLTVFLGPYLTSVAKTAADSEGYVHPLGIPVAAGSFFAYTVSLSVILAIVVMPLAGAAADRTGRKKPLLALSAYLGAAATAGMFFLDGDRYLLGGLLLVVANASLAVSMVLYNSYLPQIAEPEERDAVSSKGWAFGYASGALVLLANLVLYTAHDSFGLDEATAVRICLASAGVWWGAFTLVPLRRLRDRRLPAEAVGARRGGWGQLVATVKDMRRHPLTLGFLLAYLMYNDGVQTVISQASVFGSEELGLDQSTLIVAVLLVQVLAVAGALGMGRLARSHGARNTILGSLVVWTLILAAGYFLPAGSPVWFFVLAAFIGTVLGGTQALSRSLFSHLVPAGKEAEYFAAFEMSDRGMSWLGPLLFGLTYQFTGSYRDAILSLILFFVIGFVLLARVPVRRAVLDAGNPVPGRI
>NC_020990.1|WP_015508184.1|6133745_6134504_-|glycerophosphodiester-phosphodiesterase
MARHPYLDHPGPLPFAHRGGAAGGRENTAAAFAEAVAAGYRYLETDVHLTADGVLAAFHDPTLDRVTDRAGRIADLPWSEVARARVAGSEPVPRFEELLERFPEARWNVDVKAEPALVPLLELVRRTGAWDRVCVGSFSESRVARARRLGGPRLATSYGIGGVLGLRLRSWGLPAPVRGSAVCVQVPEAQYGVPVVDRRFLRAAHVRGLQVHVWTVNDPRRMAALLDLGVDGIMTDHIGTLRDVLRDRGQWA
>NC_020990.1|WP_015508185.1|6134518_6135178_-|membrane-protein
MFLAPRPHTRRLPRRLFQLFTGLTLYGVSVALLVRGGLGLEPWGVFQQGLSELTGLTMGTVSVVVGAAVLLLWIPLRQRPGFGTVCNVFVVGLALDATLAVLPAVEPLAARVALMISGVVLNGAATGLYIAARFGPGPRDGLMTGLHQATGRSVRLVRTGIEVLVVASGFLLGGTVGIGTVVYALSIGPLAQWFLRLFAVPAAPAPAPAPAPGGAILRP
>NC_020990.1|WP_010636502.1|6135277_6136804_+|PLP-dependent-aminotransferase-family-protein
MTEWTSVTGAAQLARLLASQSWQTRTGPGGRRPPAYRALADGVRLLILEGRLPVAARLPAERELALALAVSRTTVAAAYEALRSEGFLASRRGAGSWTAVPAGNPLPARGLEPLPPEALGALIDLGCASLPAPEPWLTRAVTGALESLPPYAMTHGDYPAGLPDLRATLAERYTRLGIPTMPEQIMVTTGAMGAIDAICHLFAPQGERIAVESPSYANILQLMREAGARLVPVAMADQLRGWDLDRWRQVLRDAAPRLAYVVADFHNPTGALADEEQRRALVEAARSAGTVLVVDETMTELALDPELAPAPDGTSALPRRVCAFDPAGSTVITVGSASKAFWAGMRIGWVRAAPDVIRRLVSARAYADLGTPVLEQLAVHWLLSGGGWEEAVRLRRDQARENRDTLVAAVRRELPDWSFEVPRGGLTLWVRTGGLSGSRIAALGEQVGIRVPSGPRFGVDGAFEGYVRLPFTVGGAVADEAAVRLAAAARLVRDGVRGGAESPRSVVA
>NC_020990.1|WP_003946964.1|6136859_6138434_-|hypothetical-protein
MARRPLPSILRGGTAPIVRSRELARSAADNATDVLHPLITIGRGLRRLAAAGRRKWAATPKDRRGPLLFLIAAVLLVLSLLRYGLPLAGAALLAVAAWTGRDRKPAAPAGDDDARSQRLTSLYESLVPYFSVPDDPAPLYTYGGDREKAFAAHSFDESGHPDRLVLRYPGYFTDAEPESRLRVEQVLAAKLGRGREYRFDWNEQGNELTVTAVAPLPCDLTAQPFATTPGEHLLGFTDAADTARTLPVTGPDGDPRDEPPVLWRTGARATEPHLLAVGHPGSGTTSLLRSLALQALRHGDVLVVDGGGAGEYACLTGREGVLAVECDLDGALTGLEWACHETERRLIAAGRARQEGHPPPPDTRRPLWILLDRPAALAHLAEAEGRTDPQSLLQVPLRHGRAAQVTVVVAEQFDSTEALTEPVRRHTRARVVLGRASAAQVALVLGAPPNTSTPVAAPPGRGWVRLGDGPVQRLQVPAAPDPYDEGTAEADRRAVLELLPPRPQPLPVPPAPTEPPVVRAGADL
>NC_020990.1|WP_003946963.1|6138465_6138660_-|hypothetical-protein
MILSMSGVVLLGIIVFLFFRKDGLKASHAVVCALFGFYLAGTAIAPSITAGGASLAGLLGGIKF

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_020990_8	8.1|2112546|39|NC_020990|CRISPRCasFinder	2112546-2112584	39	NC_020990.1	2634183-2634221	1	0.974
NC_020990_21	21.1|3849196|38|NC_020990|CRISPRCasFinder	3849196-3849233	38	NC_020990.1	3877271-3877308	1	0.974
NC_020990_15	15.1|2871420|21|NC_020990|PILER-CR	2871420-2871440	21	NC_020990.1	4250212-4250232	2	0.905
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_020990.1	3217964-3217993	2	0.933
NC_020990_20	20.1|3794165|41|NC_020990|CRISPRCasFinder	3794165-3794205	41	NC_020990.1	2440842-2440882	2	0.951
NC_020990_20	20.1|3794165|41|NC_020990|CRISPRCasFinder	3794165-3794205	41	NC_020990.1	3877270-3877310	2	0.951
NC_020990_21	21.1|3849196|38|NC_020990|CRISPRCasFinder	3849196-3849233	38	NC_020990.1	3264274-3264311	2	0.947

1. spacer 8.1|2112546|39|NC_020990|CRISPRCasFinder matches to position: 2634183-2634221, mismatch: 1, identity: 0.974

tgtgtgccgggctccctctcgaccgtgccggtcaaagac	CRISPR spacer
tgtgtgccgggctccgtctcgaccgtgccggtcaaagac	Protospacer
*************** ***********************

2. spacer 21.1|3849196|38|NC_020990|CRISPRCasFinder matches to position: 3877271-3877308, mismatch: 1, identity: 0.974

tggttgccgggctccgtctcgaccgtgccggtcaccga	CRISPR spacer
tggttgccgggctccgtctcgaccgtgccggtcactga	Protospacer
***********************************.**

3. spacer 15.1|2871420|21|NC_020990|PILER-CR matches to position: 4250212-4250232, mismatch: 2, identity: 0.905

ggtgacgctcggccccaccgc	CRISPR spacer
ggtgacggtcgggcccaccgc	Protospacer
******* **** ********

4. spacer 17.4|3218180|30|NC_020990|CRT matches to position: 3217964-3217993, mismatch: 2, identity: 0.933

tcccgacggaagccaccctcacgacggtca	CRISPR spacer
tcgcgccggaagccaccctcacgacggtca	Protospacer
** ** ************************

5. spacer 20.1|3794165|41|NC_020990|CRISPRCasFinder matches to position: 2440842-2440882, mismatch: 2, identity: 0.951

atcggtgaccggcacggtcgagacggagcccggcaacccac	CRISPR spacer
atcggtgaccggcacggtcgagacggaccccggcaaccgac	Protospacer
*************************** ********** **

6. spacer 20.1|3794165|41|NC_020990|CRISPRCasFinder matches to position: 3877270-3877310, mismatch: 2, identity: 0.951

atcggtgaccggcacggtcgagacggagcccggcaacccac	CRISPR spacer
atcagtgaccggcacggtcgagacggagcccggcaaccaac	Protospacer
***.********************************** **

7. spacer 21.1|3849196|38|NC_020990|CRISPRCasFinder matches to position: 3264274-3264311, mismatch: 2, identity: 0.947

tggttgccgggctccgtctcgaccgtgccggtcaccga	CRISPR spacer
tggttgccgggctccgtcccgaccgtgccggtcactga	Protospacer
******************.****************.**

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_020990_3	3.8|1220850|27|NC_020990|PILER-CR	1220850-1220876	27	NC_013449	Streptomyces sp. W9 plasmid pCQ3, complete sequence	48875-48901	0	1.0
NC_020990_15	15.1|2871420|21|NC_020990|PILER-CR	2871420-2871440	21	NZ_CP026518	Deinococcus sp. NW-56 plasmid unnamed2, complete sequence	5642-5662	1	0.952
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	NZ_AP014810	Methylorubrum populi strain P-1M plasmid pMPPM01, complete sequence	40927-40949	1	0.957
NC_020990_3	3.3|1220844|36|NC_020990|CRISPRCasFinder	1220844-1220879	36	NC_013449	Streptomyces sp. W9 plasmid pCQ3, complete sequence	48872-48907	2	0.944
NC_020990_15	15.1|2871420|21|NC_020990|PILER-CR	2871420-2871440	21	NZ_CP047174	Rathayibacter sp. VKM Ac-2760 plasmid unnamed1, complete sequence	128902-128922	2	0.905
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	NZ_CP036181	Escherichia coli strain WCHEC025970 plasmid p2_025970, complete sequence	89268-89290	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	489154-489176	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	639925-639947	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	NZ_MG825377	Escherichia coli strain 1108 plasmid p1108-emrB, complete sequence	87779-87801	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	KX781992	Mycobacterium phage Gabriel, complete genome	14656-14678	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	MK359346	Mycobacterium phage NoodleTree, complete genome	15770-15792	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	JN699013	Mycobacterium phage Pio, complete genome	16631-16653	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	MT740732	Ralstonia phage Darius, complete genome	20472-20494	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	AY129337	Mycobacteriophage Bxz1, complete genome	16242-16264	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	MK112545	Mycobacterium phage Khaleesi, complete genome	15317-15339	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	MH825697	Mycobacterium phage Bangla1971, complete genome	15233-15255	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	MK359342	Mycobacterium phage ShiaLabeouf, complete genome	14860-14882	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	MT740740	Ralstonia phage Gervaise, complete genome	28918-28940	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	NC_004687	Mycobacterium phage Bxz1, complete genome	16242-16264	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	MK359321	Mycobacterium phage Phusco, complete genome	15233-15255	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	NC_029044	Mycobacterium phage Breeniome, complete genome	14665-14687	2	0.913
NC_020990_30	30.2|5367253|23|NC_020990|PILER-CR	5367253-5367275	23	JN204348	Mycobacterium phage Sebata, complete genome	16349-16371	2	0.913
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	MH155873	Microbacterium phage Paschalis, complete genome	42250-42277	3	0.893
NC_020990_24	24.1|4432020|30|NC_020990|CRISPRCasFinder	4432020-4432049	30	NZ_CP023976	Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence	217864-217893	3	0.9
NC_020990_30	30.1|5367192|23|NC_020990|PILER-CR	5367192-5367214	23	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	141042-141064	3	0.87
NC_020990_32	32.3|6127816|25|NC_020990|CRISPRCasFinder	6127816-6127840	25	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	21640-21664	3	0.88
NC_020990_1	1.1|801289|29|NC_020990|CRISPRCasFinder	801289-801317	29	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	270589-270617	4	0.862
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP025510	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence	139354-139380	4	0.852
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP025510	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence	139480-139506	4	0.852
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP025510	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence	139606-139632	4	0.852
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP025510	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence	139732-139758	4	0.852
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP025510	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence	139858-139884	4	0.852
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP025510	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence	139984-140010	4	0.852
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP025510	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence	140110-140136	4	0.852
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NC_031255	Gordonia phage Schwabeltier, complete genome	37926-37955	4	0.867
NC_020990_32	32.3|6127816|25|NC_020990|CRISPRCasFinder	6127816-6127840	25	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	1339647-1339671	4	0.84
NC_020990_32	32.3|6127816|25|NC_020990|CRISPRCasFinder	6127816-6127840	25	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	1344315-1344339	4	0.84
NC_020990_32	32.3|6127816|25|NC_020990|CRISPRCasFinder	6127816-6127840	25	NZ_AP022333	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence	260113-260137	4	0.84
NC_020990_32	32.3|6127816|25|NC_020990|CRISPRCasFinder	6127816-6127840	25	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	761511-761535	4	0.84
NC_020990_32	32.3|6127816|25|NC_020990|CRISPRCasFinder	6127816-6127840	25	NZ_CP036516	Lichenihabitans psoromatis strain PAMC 29148 plasmid p_unnamed1, complete sequence	74034-74058	4	0.84
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP039925	Agrobacterium tumefaciens strain CFBP7129 plasmid pAtCFBP7129b, complete sequence	283360-283386	5	0.815
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP031468	Paraburkholderia caffeinilytica strain CF1 plasmid p1, complete sequence	159737-159763	5	0.815
NC_020990_3	3.8|1220850|27|NC_020990|PILER-CR	1220850-1220876	27	NZ_CP010187	Escherichia coli strain M6 plasmid A, complete genome	31982-32008	5	0.815
NC_020990_3	3.8|1220850|27|NC_020990|PILER-CR	1220850-1220876	27	NZ_CP010207	Escherichia coli strain M11 plasmid A, complete sequence	125957-125983	5	0.815
NC_020990_3	3.8|1220850|27|NC_020990|PILER-CR	1220850-1220876	27	NZ_CP010197	Escherichia coli strain M9 plasmid A, complete genome	31982-32008	5	0.815
NC_020990_3	3.8|1220850|27|NC_020990|PILER-CR	1220850-1220876	27	NZ_CP010222	Escherichia coli strain M19 plasmid A, complete sequence	31982-32008	5	0.815
NC_020990_3	3.8|1220850|27|NC_020990|PILER-CR	1220850-1220876	27	NZ_CP010214	Escherichia coli strain M15 plasmid A, complete sequence	102655-102681	5	0.815
NC_020990_16	16.1|3158476|37|NC_020990|CRISPRCasFinder	3158476-3158512	37	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	173873-173909	5	0.865
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP007257	Rhodococcus erythropolis R138 plasmid pLRE138, complete sequence	237945-237974	5	0.833
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP045736	Aeromicrobium sp. MF47 plasmid p001, complete sequence	28688-28717	5	0.833
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NC_014549	Glutamicibacter arilaitensis Re117 plasmid pRE117-1, complete sequence	34721-34750	5	0.833
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NC_008537	Arthrobacter sp. FB24 plasmid 1, complete sequence	125352-125381	5	0.833
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NC_009235	Burkholderia phage phi644-2 chromosome, complete genome	31493-31522	5	0.833
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	CP000625	Burkholderia phage phi644-2, complete genome	31493-31522	5	0.833
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	AF447491	Bacteriophage phiE125, complete genome	37188-37217	5	0.833
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NC_003309	Burkholderia phage phiE125, complete genome	37188-37217	5	0.833
NC_020990_1	1.1|801289|29|NC_020990|CRISPRCasFinder	801289-801317	29	NC_015057	Granulicella tundricola MP5ACTX9 plasmid pACIX901, complete sequence	151913-151941	6	0.793
NC_020990_1	1.1|801289|29|NC_020990|CRISPRCasFinder	801289-801317	29	NZ_CP044073	Pseudomonas oryzihabitans strain FDAARGOS_657 plasmid unnamed2, complete sequence	80750-80778	6	0.793
NC_020990_3	3.6|1220844|41|NC_020990|CRT	1220844-1220884	41	NC_013449	Streptomyces sp. W9 plasmid pCQ3, complete sequence	48867-48907	6	0.854
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	355963-355989	6	0.778
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP013072	Sphingobium indicum B90A plasmid pSRL2, complete sequence	80753-80779	6	0.778
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NC_008381	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL10, complete sequence	70377-70403	6	0.778
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_LR699074	Beijerinckiaceae bacterium RH AL1 isolate RH_AL1 plasmid 2	90893-90919	6	0.778
NC_020990_3	3.7|1220789|27|NC_020990|PILER-CR	1220789-1220815	27	NZ_CP005190	Sphingobium sp. MI1205 plasmid pMI1, complete sequence	83035-83061	6	0.778
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	495822-495853	6	0.812
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	584424-584455	6	0.812
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_KJ588780	Achromobacter xylosoxidans strain A22732 plasmid pA22732-IMP, complete sequence	21977-22004	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_MN366359	Bacterium plasmid pALTS31, complete sequence	19571-19598	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_001735	Enterobacter aerogenes plasmid R751, complete sequence	39916-39943	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	AGRM01000006	Salmonella enterica subsp. houtenae str. ATCC BAA-1581 plasmid pSEHO0A1, complete sequence, whole genome shotgun sequence	14761-14788	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_017908	Mycobacterium abscessus subsp. bolletii F1725 plasmid BRA100, complete sequence	19693-19720	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	AJ863570	Uncultured bacterium IncP-1beta multiresistance plasmid pB8	34510-34537	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	KU238092	Uncultured bacterium plasmid pDTC28, complete sequence	18689-18716	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JX469834	Uncultured bacterium plasmid pDS3, complete sequence	17318-17345	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JX469831	Uncultured bacterium plasmid pKSP212, complete sequence	24158-24185	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JN106172	Uncultured bacterium plasmid pAKD29, complete sequence	17157-17184	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JN106173	Uncultured bacterium plasmid pAKD31, complete sequence	18335-18362	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JN106174	Uncultured bacterium plasmid pAKD33, complete sequence	18338-18365	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JN106164	Uncultured bacterium plasmid pAKD1, complete sequence	30488-30515	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JN106165	Uncultured bacterium plasmid pAKD14, complete sequence	18335-18362	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JN106166	Uncultured bacterium plasmid pAKD15, complete sequence	18335-18362	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JN106168	Uncultured bacterium plasmid pAKD17, complete sequence	18335-18362	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JN106169	Uncultured bacterium plasmid pAKD18, complete sequence	18320-18347	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_014911	Alicycliphilus denitrificans BC plasmid pALIDE02, complete sequence	903-930	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	MN386974	Pseudomonas aeruginosa strain 1943 plasmid pPaeBURNS1, complete sequence	26512-26539	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	640261-640288	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	MG879028	Uncultured bacterium plasmid pEG1-1, complete sequence	50544-50571	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_CP021650	Acidovorax sp. T1 plasmid p2-T1, complete sequence	640-667	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	KF743817	Proteus mirabilis plasmid R772, complete sequence	17250-17277	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	KF743818	Bordetella bronchiseptica plasmid R906, complete sequence	19468-19495	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	JX486125	Uncultured bacterium plasmid pRWC72a, complete sequence	29045-29072	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_CP038640	Cupriavidus oxalaticus strain X32 plasmid unnamed5, complete sequence	52690-52717	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	AJ639924	Uncultured bacterium plasmid pB3 complete genome	34225-34252	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	KC170279	Uncultured bacterium plasmid pMBUI8, complete sequence	29304-29331	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	KU356987	Variovorax paradoxus plasmid pBS64, complete sequence	34735-34762	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	KU356988	Variovorax paradoxus plasmid pHB44, complete sequence	33440-33467	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_CP009797	Burkholderia ambifaria AMMD plasmid pBII_1, complete sequence	20075-20102	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_013176	Pseudomonas putida plasmid pW2, complete sequence	13452-13479	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_019320	Variovorax sp. DB1 plasmid pDB1, complete sequence	51764-51791	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_CP017455	Dickeya solani strain PPO 9019 plasmid unnamed, complete sequence	27166-27193	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_007337	Cupriavidus pinatubonensis JMP134 plasmid 1, complete sequence	74183-74210	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_MN366358	Bacterium plasmid pALTS29, complete sequence	30966-30993	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_005088	Delftia acidovorans B plasmid pUO1, complete sequence	44965-44992	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_CP018471	Xanthomonas vesicatoria strain LM159 plasmid pLM159.2, complete sequence	56795-56822	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_KP289281	Pseudomonas sp. EGD-AKN5 plasmid unnamed, complete sequence	23637-23664	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_CP015373	Pandoraea pnomenusa strain MCB032 plasmid unnamed 2, complete sequence	44536-44563	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_AP017604	Sphingopyxis sp. EG6 plasmid pSREG01, complete sequence	14379-14406	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	17953-17980	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	6012408-6012435	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	AP018709	Uncultured bacterium plasmid pSN1104-59 DNA, complete sequence	25060-25087	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_004956	Pseudomonas sp. ADP atrazine catabolic plasmid pADP-1, complete sequence	23637-23664	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_CP019238	Rhodoferax koreense strain DCY-110 plasmid unnamed2	48391-48418	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	121926-121953	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_019312	Delftia sp. KV29 plasmid pKV29, complete sequence	33135-33162	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_021077	Comamonas sp. 7D-2 plasmid pBHB, complete sequence	102085-102112	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_024998	Acidovorax avenae subsp. avenae plasmid pAAA83 DNA, complete sequence, strain: 83	21067-21094	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_MH053445	Pseudomonas aeruginosa strain PA1280 plasmid pICP-4GES, complete sequence	32280-32307	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	AM157767	Uncultured bacterium IncP-1gamma plasmid QKH54 complete genome	46495-46522	6	0.786
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_008385	Burkholderia ambifaria AMMD plasmid unnamed1, complete sequence	26359-26386	6	0.786
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052329	Klebsiella pneumoniae strain D17KP0032 plasmid pD17KP0032-1, complete sequence	98664-98693	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_KY271405	Klebsiella pneumoniae strain H151440672 plasmid pKPN3-307_typeB, complete sequence	63546-63575	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP025142	Klebsiella pneumoniae strain KP1768 plasmid KP1768_p2, complete sequence	127059-127088	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP026135	Klebsiella pneumoniae strain F5 plasmid pF5_3, complete sequence	19306-19335	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018434	Klebsiella pneumoniae strain MNCRE53 plasmid pMNCRE53_4, complete sequence	52271-52300	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP043049	Klebsiella pneumoniae strain KLP268 plasmid pKLP268-3	140891-140920	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP040123	Klebsiella pneumoniae strain LSH-KPN148 plasmid pLSH-KPN148-1, complete sequence	10935-10964	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP034282	Klebsiella pneumoniae strain I72 plasmid p72_FIBkpn, complete sequence	84789-84818	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP050830	Klebsiella pneumoniae strain Bckp067 plasmid pBckp067, complete sequence	127695-127724	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_009649	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 plasmid pKPN3, complete sequence	64902-64931	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP011977	Klebsiella pneumoniae DMC1097 plasmid pDMC1097-218.836kb, complete sequence	103771-103800	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP041928	Klebsiella pneumoniae strain 18-2374 plasmid pSECR18-2374A, complete sequence	61571-61600	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP010393	Klebsiella pneumoniae strain 34618 plasmid p34618-207.543kb, complete sequence	51590-51619	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_022078	Klebsiella pneumoniae JM45 plasmid p1, complete sequence	187455-187484	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP027037	Klebsiella pneumoniae strain 16_GR_13 plasmid IncFIB IncFII, complete sequence	110703-110732	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_023332	Klebsiella pneumoniae strain ST48 plasmid pKP09085, complete sequence	30491-30520	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_023333	Klebsiella pneumoniae strain ST23 plasmid pKP007, complete sequence	27714-27743	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_023334	Klebsiella pneumoniae strain ST15 plasmid pKP02022, complete sequence	27715-27744	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP020499	Klebsiella pneumoniae strain BWHC1 plasmid unnamed1, complete sequence	55080-55109	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP025038	Klebsiella pneumoniae strain NU-CRE047 plasmid pNU-CRE047_1, complete sequence	115496-115525	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018693	Klebsiella pneumoniae strain Kp_Goe_821588 plasmid pKp_Goe_588-1, complete sequence	108785-108814	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP020855	Klebsiella pneumoniae strain KPN528 plasmid pKPN528-2, complete sequence	152710-152739	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	LC549807	Klebsiella pneumoniae VNCKp115 plasmid pVNCKp115 DNA, complete sequence	150023-150052	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP027054	Klebsiella pneumoniae strain 2_GR_12 plasmid IncFIB IncFII	68113-68142	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP023479	Klebsiella quasipneumoniae strain KPC142 plasmid pKQPS142a, complete sequence	122167-122196	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018424	Klebsiella pneumoniae strain MNCRE69 plasmid pMNCRE69_4, complete sequence	52271-52300	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP029591	Klebsiella pneumoniae strain DA33144 plasmid pDA33144-220, complete sequence	114603-114632	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_021654	Klebsiella pneumoniae plasmid pKN-LS6, complete sequence	128897-128926	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_016966	Klebsiella pneumoniae plasmid pUUH239.2, complete sequence	27714-27743	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP042482	Klebsiella pneumoniae strain C51 plasmid pC51_001, complete sequence	107539-107568	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP022920	Klebsiella pneumoniae strain ST307PT03 plasmid pJYC03A, complete sequence	177285-177314	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP012572	Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-6.X, complete sequence	119609-119638	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP029136	Klebsiella pneumoniae strain AR376 plasmid unnamed2, complete sequence	81742-81771	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP014121	Klebsiella pneumoniae strain FDAARGOS_156 plasmid unnamed1, complete sequence	11236-11265	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP041640	Klebsiella pneumoniae strain PIMB15ND2KP27 plasmid pKP27-MPH, complete sequence	20101-20130	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP043854	Enterobacter hormaechei strain EB_P6_L3_02.19 plasmid unnamed1, complete sequence	49269-49298	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP026752	Klebsiella pneumoniae strain AR_0066 plasmid tig00000080_pilon, complete sequence	57934-57963	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052209	Klebsiella pneumoniae strain E17KP0085 plasmid pE17KP0085-2, complete sequence	125472-125501	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP026179	Klebsiella pneumoniae strain KPNIH49 plasmid pKPC-224e, complete sequence	119087-119116	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018355	Klebsiella pneumoniae strain CAV1453 plasmid pCAV1453-208, complete sequence	198549-198578	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP031614	Klebsiella pneumoniae strain ZYST1 plasmid pZYST1C1, complete sequence	144812-144841	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_AP019689	Klebsiella quasipneumoniae strain SNI47 plasmid pTMSNI47-2, complete sequence	120605-120634	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	LT009688	Klebsiella pneumoniae plasmid pIT-06C07, strain O6CO7, complete sequence	28500-28529	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP009777	Klebsiella pneumoniae subsp. pneumoniae strain KPNIH32 plasmid pKPN-a68, complete sequence	46723-46752	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP008800	Klebsiella pneumoniae subsp. pneumoniae KPNIH24 plasmid pKPN-e44, complete sequence	81011-81040	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP046940	Klebsiella pneumoniae strain BD_DM_697 plasmid punnamed1	75322-75351	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP006927	Klebsiella pneumoniae 30660/NJST258_1 plasmid pNJST258N1, complete sequence	46053-46082	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP008930	Klebsiella pneumoniae strain PMK1 plasmid pPMK1-A, complete sequence	91611-91640	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP007729	Klebsiella pneumoniae subsp. pneumoniae KPNIH10 plasmid pKPN-498, complete sequence	93471-93500	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP006663	Klebsiella pneumoniae strain ATCC BAA-2146 plasmid pCuAs, complete sequence	63143-63172	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP029143	Klebsiella michiganensis strain AR375 plasmid unnamed3, complete sequence	72072-72101	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP048380	Klebsiella variicola strain 118 plasmid p118_A, complete sequence	98627-98656	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP020109	Klebsiella pneumoniae strain AR_0098 plasmid tig00000001, complete sequence	4880-4909	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP020069	Klebsiella pneumoniae strain AR_0068 plasmid unitig_2, complete sequence	207743-207772	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP012567	Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-6, complete sequence	152895-152924	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP036443	Klebsiella pneumoniae strain ABFPV plasmid tig00001208_pilon, complete sequence	88943-88972	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP050379	Klebsiella pneumoniae strain 51015 plasmid p51015_CTX_M_15, complete sequence	68692-68721	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP034130	Klebsiella quasipneumoniae strain G4584 plasmid pG4584_218.9Kb, complete sequence	129961-129990	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	MF918373	Klebsiella pneumoniae plasmid p1512-dfrA, complete sequence	76875-76904	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP050374	Klebsiella pneumoniae strain 50595 plasmid p50595_NDM_1, complete sequence	59080-59109	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP012884	Klebsiella pneumoniae KP-1 plasmid pKP1-19, complete sequence	15866-15895	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP028804	Klebsiella pneumoniae strain WCHKP7E2 plasmid pCMY2_085072, complete sequence	139250-139279	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP030343	Klebsiella pneumoniae strain AR_362 plasmid unnamed1, complete sequence	57224-57253	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018460	Klebsiella pneumoniae strain Kp_Goe_39795 plasmid pKp_Goe_795-1, complete sequence	71523-71552	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP020903	Klebsiella pneumoniae strain K66-45 plasmid pK66-45-2, complete sequence	53846-53875	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP026212	Citrobacter sp. CFNIH10 plasmid pCIT-a850, complete sequence	108536-108565	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP021856	Klebsiella pneumoniae strain AR_0125 plasmid tig00000001_pilon, complete sequence	47369-47398	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP034138	Klebsiella quasipneumoniae subsp. similipneumoniae strain G747 plasmid pG747_218.9Kb, complete sequence	129958-129987	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP027049	Klebsiella pneumoniae strain 20_GR_12 plasmid unnamed, complete sequence	46846-46875	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	MN823998	Klebsiella pneumoniae strain 161116753 plasmid p116753-FIIK, complete sequence	127123-127152	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	MN823999	Klebsiella pneumoniae strain 362713 plasmid p362713-FIIK, complete sequence	35183-35212	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP031809	Klebsiella pneumoniae strain INF206-sc-2280074 plasmid unnamed, complete sequence	173850-173879	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP032186	Klebsiella pneumoniae strain AR_0075 plasmid unnamed1, complete sequence	109877-109906	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP027152	Klebsiella pneumoniae strain AR_0363 plasmid unnamed1, complete sequence	203516-203545	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018365	Klebsiella pneumoniae strain Kp_Goe_62629 plasmid pKp_Goe_629-1, complete sequence	92745-92774	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_020132	Klebsiella pneumoniae strain BK32179 plasmid pBK32179, complete sequence	51447-51476	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_024992	Klebsiella pneumoniae plasmid pKp848CTX, complete sequence	50894-50923	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP023947	Klebsiella pneumoniae strain FDAARGOS_446 plasmid unnamed2, complete sequence	43300-43329	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP031369	Klebsiella pneumoniae strain KpvST101_OXA-48 plasmid pKpvST101, complete sequence	12270-12299	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_AP014952	Klebsiella oxytoca strain JKo3 plasmid pKO_JKo3_1, complete sequence	147077-147106	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_LR025089	Klebsiella pneumoniae isolate KP980 plasmid 2, complete sequence	149702-149731	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP054265	Klebsiella pneumoniae strain 39427 plasmid pKPN39427.1, complete sequence	116477-116506	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP021951	Klebsiella pneumoniae strain AR_0148 plasmid tig00000168_pilon, complete sequence	97927-97956	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP050823	Klebsiella pneumoniae strain Bckp091 plasmid pBckp091-1, complete sequence	29076-29105	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP025145	Klebsiella pneumoniae strain NR5632 plasmid NR5632_p2, complete sequence	123987-124016	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP025148	Klebsiella pneumoniae strain KP1766 plasmid KP1766_p2, complete sequence	136815-136844	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP036188	Klebsiella pneumoniae strain BA1559 plasmid pIncFIBK, complete sequence	38422-38451	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052469	Klebsiella pneumoniae strain C16KP0053 plasmid pC16KP0053-1, complete sequence	50857-50886	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP015383	Klebsiella pneumoniae strain CN1 plasmid pCN1_1, complete sequence	54379-54408	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP023943	Klebsiella pneumoniae strain FDAARGOS_444 plasmid unnamed1, complete sequence	71833-71862	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP027696	Klebsiella pneumoniae strain KP30835 plasmid unnamed1, complete sequence	64454-64483	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	MN823997	Klebsiella pneumoniae strain 111119051 plasmid p19051-FIIK, complete sequence	89817-89846	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP035536	Klebsiella pneumoniae subsp. pneumoniae strain CCRI-22199 plasmid pKp199-1, complete sequence	162962-162991	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_KY271404	Klebsiella pneumoniae strain Kp-48 plasmid pKPN3-307_typeA, complete sequence	121854-121883	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_MG288676	Klebsiella pneumoniae strain F160070 plasmid p160070-catA, complete sequence	38755-38784	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	LR134219	Klebsiella aerogenes strain NCTC10317 genome assembly, plasmid: 3	90750-90779	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018351	Klebsiella pneumoniae strain CAV1417 plasmid pCAV1417-185, complete sequence	70386-70415	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018675	Klebsiella pneumoniae strain CAV1217 plasmid pKPC_CAV1217, complete sequence	87650-87679	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052168	Klebsiella pneumoniae strain F16KP0075 plasmid pF16KP0075-1, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP014073	Klebsiella quasipneumoniae strain FDAARGOS_93 plasmid unnamed2, complete sequence	64406-64435	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_KX636095	Klebsiella pneumoniae strain RJ119 plasmid pRJ119-NDM1, complete sequence	168938-168967	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052485	Klebsiella pneumoniae strain C16KP0036 plasmid pC16KP0036-1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_KT203286	Klebsiella pneumoniae strain U25 plasmid PU25001, complete sequence	182661-182690	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP021752	Klebsiella pneumoniae strain AR_0113 plasmid unitig_1, complete sequence	133151-133180	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP050844	Klebsiella pneumoniae strain Bckp186 plasmid pBckp186, complete sequence	207554-207583	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP022125	Klebsiella pneumoniae strain DHQP1605752_NV plasmid p1605752FIB, complete sequence	66561-66590	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018441	Klebsiella pneumoniae strain Kp_Goe_822917 plasmid pKp_Goe_917-1, complete sequence	27527-27556	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP029588	Klebsiella pneumoniae strain DA33141 plasmid pDA33141-217, complete sequence	40700-40729	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052408	Klebsiella pneumoniae strain C17KP0008 plasmid pC17KP0008-1, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP035216	Klebsiella michiganensis strain M82255 plasmid pKOCBH-B, complete sequence	152376-152405	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP014649	Klebsiella pneumoniae strain KPNIH36 plasmid pKPN-fff, complete sequence	112476-112505	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP024193	Klebsiella pneumoniae isolate KSB1_5D plasmid unnamed2, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052401	Klebsiella pneumoniae strain C17KP0039 plasmid pC17KP0039-2, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052572	Klebsiella pneumoniae strain A16KP0016 plasmid pA16KP0016-1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	MN543573	Klebsiella pneumoniae strain GH44 plasmid pGH44_216, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP028954	Klebsiella pneumoniae strain AR_0141 plasmid unnamed1, complete sequence	132449-132478	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP033627	Klebsiella pneumoniae strain 4743 plasmid unnamed2, complete sequence	43305-43334	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP036302	Klebsiella pneumoniae subsp. pneumoniae strain WCHKP015093 plasmid p1_015093, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_LR130542	Klebsiella pneumoniae strain AJ218 isolate AJ218 plasmid 2	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052405	Klebsiella pneumoniae strain C17KP0020 plasmid pC17KP0020-1, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP020842	Klebsiella pneumoniae strain KPN1482 plasmid pKPN1482-1, complete sequence	56717-56746	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP031811	Klebsiella pneumoniae strain INF014-sc-2279884 plasmid unnamed1, complete sequence	34152-34181	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	MN891675	Klebsiella pneumoniae strain 358573 plasmid p358573-KPC, complete sequence	163077-163106	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP020838	Klebsiella pneumoniae strain BK13043 plasmid pBK13043-1, complete sequence	195497-195526	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP028784	Klebsiella pneumoniae strain SCKP020049 plasmid p1_020049, complete sequence	42162-42191	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052218	Klebsiella pneumoniae strain E17KP0053 plasmid pE17KP0053-1, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP031735	Klebsiella pneumoniae subsp. pneumoniae strain Klebsiella pneumoniae plasmid pKPM501, complete sequence	43398-43427	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018818	Klebsiella pneumoniae strain AR_0049 plasmid unitig_2, complete sequence	34266-34295	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP037966	Klebsiella pneumoniae strain SCKP020135 plasmid p1_020135, complete sequence	42162-42191	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052148	Klebsiella pneumoniae strain F16KP0108 plasmid pF16KP0108-1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP041084	Klebsiella pneumoniae strain Kp202 plasmid pKp202_2, complete sequence	44639-44668	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP036337	Klebsiella pneumoniae strain BP327 plasmid pIncFIBK, complete sequence	165568-165597	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052415	Klebsiella pneumoniae strain C16KP0189 plasmid pC16KP0189-1, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052559	Klebsiella pneumoniae strain A17KP0008 plasmid pA17KP0008-2, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052270	Klebsiella pneumoniae strain E16KP0268 plasmid pE16K0268-2, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP041514	Klebsiella michiganensis strain KNU07 plasmid unnamed, complete sequence	49829-49858	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP041100	Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH07 plasmid unnamed1, complete sequence	45859-45888	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP021834	Klebsiella pneumoniae strain AR_0120 plasmid tig00000500_pilon, complete sequence	100019-100048	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP022692	Klebsiella pneumoniae subsp. pneumoniae strain AUSMDU00008079 plasmid pAUSMDU00008079_01, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP035180	Klebsiella pneumoniae strain BA33875 plasmid pBA33875_IncFIB, complete sequence	156800-156829	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP015132	Klebsiella pneumoniae strain Kpn555 plasmid pKPN-d90, complete sequence	163333-163362	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP018886	Klebsiella pneumoniae subsp. pneumoniae strain BR21 plasmid pIncF, complete sequence	54304-54333	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP039809	Klebsiella pneumoniae strain C2660 plasmid pC2660-2, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP029101	Klebsiella pneumoniae strain AR438 plasmid unnamed3, complete sequence	71590-71619	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP040025	Klebsiella pneumoniae strain KPC160132 plasmid pKpn3-L132, complete sequence	44643-44672	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052561	Klebsiella pneumoniae strain A17KP0004 plasmid pA17KP0004-1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP028995	Klebsiella pneumoniae strain AR_0079 plasmid unnamed6, complete sequence	45281-45310	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP033402	Klebsiella pneumoniae strain WCHKP115069 plasmid p1_115069, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP031583	Klebsiella pneumoniae strain N4b plasmid pIncFII-1502320, complete sequence	127958-127987	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP029598	Klebsiella quasipneumoniae subsp. similipneumoniae strain ATCC 700603 plasmid pDA33145-152, complete sequence	93556-93585	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP047337	Klebsiella pneumoniae strain 2019036D plasmid p2019036D-mcr8-345kb, complete sequence	69575-69604	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP021544	Klebsiella pneumoniae strain AR_0112 plasmid tig00000000, complete sequence	12396-12425	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP021540	Klebsiella pneumoniae strain AR_0047 plasmid tig00000001, complete sequence	23040-23069	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP021686	Klebsiella pneumoniae strain AR_0146 plasmid tig00001160, complete sequence	89941-89970	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP022926	Klebsiella pneumoniae strain ST307PT01 plasmid pJYC01A, complete sequence	90981-91010	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	KT896504	Klebsiella pneumoniae strain I11 plasmid pKPSH11, complete sequence	45457-45486	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP009879	Klebsiella pneumoniae subsp. pneumoniae strain KPNIH31 plasmid pKPN-c22, complete sequence	16739-16768	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP046950	Klebsiella pneumoniae strain BD_DM_914 plasmid punnamed1, complete sequence	44643-44672	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052288	Klebsiella pneumoniae strain E16KP0218 plasmid pE16KP0218-2, complete sequence	44643-44672	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP022824	Klebsiella quasivariicola strain KPN1705 plasmid pKPN1705-1, complete sequence	47065-47094	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP020072	Klebsiella pneumoniae strain AR_0115 plasmid tig00000002, complete sequence	4553-4582	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP015386	Klebsiella pneumoniae strain NY9 plasmid pNY9_1, complete sequence	46774-46803	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP024537	Klebsiella pneumoniae strain KSB1_9D plasmid unnamed2, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP024516	Klebsiella pneumoniae strain KSB1_10J plasmid unnamed1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052276	Klebsiella pneumoniae strain E16KP0241 plasmid pE16KP0241-1, complete sequence	44643-44672	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052298	Klebsiella pneumoniae strain E16KP0204 plasmid pE16KP0204-1, complete sequence	44643-44672	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_LR130549	Klebsiella pneumoniae strain KPC2 isolate KPC2 plasmid 2	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP046382	Klebsiella pneumoniae strain BD_DM_782 plasmid punnamed1, complete sequence	44643-44672	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP022574	Klebsiella pneumoniae strain BIC-1 plasmid pBIC-1a, complete sequence	134908-134937	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052387	Klebsiella pneumoniae strain C17KP0055 plasmid pC17KP0055-1, complete sequence	46775-46804	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NC_021198	Klebsiella pneumoniae subsp. pneumoniae KPX plasmid pKPX-1 DNA, complete sequence	136462-136491	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP021713	Klebsiella pneumoniae strain AR_0129 plasmid tig00000000, complete sequence	138980-139009	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP026151	Klebsiella pneumoniae strain F138 plasmid pF138_2, complete sequence	94433-94462	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP040030	Klebsiella pneumoniae strain KPC160121 plasmid pQnr-L121, complete sequence	44643-44672	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052538	Klebsiella pneumoniae strain B16KP0141 plasmid pB16KP0141-1, complete sequence	44643-44672	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	MF116002	Uncultured bacterium plasmid pLGP4 clone J53, complete sequence	68757-68786	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP029387	Klebsiella pneumoniae subsp. pneumoniae strain SCKP040074 plasmid pTetD_040074, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP028181	Klebsiella pneumoniae strain CFSAN054110 plasmid pGMI16-005_01, complete sequence	219898-219927	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052441	Klebsiella pneumoniae strain C16KP0102 plasmid pC16KP0102-1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_LR025093	Klebsiella pneumoniae isolate KP9201 plasmid 2, complete sequence	147809-147838	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP024500	Klebsiella pneumoniae strain KSB1_4E plasmid unnamed1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP029724	Klebsiella pneumoniae strain AR_0140 plasmid unnamed2, complete sequence	70416-70445	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052370	Klebsiella pneumoniae strain D16KP0087 plasmid pD16KP0087-1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP024508	Klebsiella pneumoniae strain KSB2_1B plasmid unnamed2, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP024551	Klebsiella pneumoniae strain INF163 plasmid unnamed2, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP032209	Klebsiella pneumoniae strain AR_0109 plasmid unnamed3, complete sequence	111015-111044	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP014697	Klebsiella quasipneumoniae strain ATCC 700603 isolate K6 plasmid pKQPS1, complete sequence	136736-136765	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	MN842293	Klebsiella pneumoniae strain 20130907-4 plasmid p309074-1FIIK, complete sequence	44372-44401	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052506	Klebsiella pneumoniae strain B16KP0226 plasmid pB16KP0226-1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052214	Klebsiella pneumoniae strain E17KP0079 plasmid pE17KP0079-1, complete sequence	44643-44672	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP015823	Klebsiella pneumoniae isolate blood sample 2 plasmid 1, complete sequence	35313-35342	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP021710	Klebsiella pneumoniae strain AR_0143 plasmid tig00000853, complete sequence	18044-18073	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP023488	Klebsiella pneumoniae subsp. pneumoniae strain ST101:960186733 plasmid p19-10_01, complete sequence	95539-95568	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052263	Klebsiella pneumoniae strain E16KP0288 plasmid pE16K0288-1, complete sequence	45995-46024	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP027161	Klebsiella pneumoniae strain AR_0361 plasmid unnamed1, complete sequence	82016-82045	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP025009	Klebsiella pneumoniae strain AUSMDU00008119 plasmid pAUSMDU8119-1, complete sequence	44692-44721	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP022917	Klebsiella pneumoniae strain ST307PT04 plasmid pJYC04A, complete sequence	237299-237328	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052237	Klebsiella pneumoniae strain E17KP0029 plasmid pE17KP0029-2, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP042883	Klebsiella pneumoniae strain NMBU-W07E18 plasmid pNMBU-W07E18_01, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052435	Klebsiella pneumoniae strain C16KP0108 plasmid pC16KP0108-1, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052140	Klebsiella pneumoniae strain F17KP0040 plasmid pF17KP0040-2, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP035211	Klebsiella pneumoniae strain TH164 plasmid pTH164-2, complete sequence	45605-45634	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052499	Klebsiella pneumoniae strain B17KP0021 plasmid pB17KP0021-1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP028543	Klebsiella pneumoniae subsp. pneumoniae strain SCKP020143 plasmid p1_020143, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP024483	Klebsiella pneumoniae strain INF322 plasmid unnamed1, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP028781	Klebsiella pneumoniae subsp. pneumoniae strain SCKP020046 plasmid pNDM5_020046, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP027425	Klebsiella oxytoca strain FDAARGOS_335 plasmid unnamed, complete sequence	117677-117706	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052477	Klebsiella pneumoniae strain C16KP0050 plasmid pC16KP0050-1, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP025006	Klebsiella pneumoniae strain AUSMDU00003562 plasmid pAUSMDU3562-1, complete sequence	44690-44719	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP026716	Klebsiella oxytoca strain AR_0028 plasmid unitig_1_pilon, complete sequence	120091-120120	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052243	Klebsiella pneumoniae strain E17KP0019 plasmid pE17KP0019-2, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP030071	Klebsiella pneumoniae strain DA12090 plasmid pDA12090.1, complete sequence	170425-170454	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP037929	Klebsiella pneumoniae subsp. pneumoniae strain KP-8788 plasmid pKPN-IT-8788, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	MN922301	Klebsiella pneumoniae strain KP-14159 plasmid pKPN-IT-14159, complete sequence	44642-44671	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_LT994840	Klebsiella pneumoniae isolate CNR48 plasmid CNR48, complete sequence	133165-133194	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP015393	Klebsiella pneumoniae strain CR14 plasmid pCR14_1, complete sequence	11222-11251	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052337	Klebsiella pneumoniae strain D17KP0018 plasmid pD17KP0018-1, complete sequence	44638-44667	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052307	Klebsiella pneumoniae strain E16KP0133 plasmid pE16KP0133-1, complete sequence	43306-43335	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_LR130540	Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2	44489-44518	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_MN268580	Klebsiella pneumoniae strain KP13-53 plasmid pKP13-53-tet(A), complete sequence	128017-128046	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_MH745929	Klebsiella pneumoniae strain VRES1611 plasmid unnamed, complete sequence	44649-44678	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP016810	Klebsiella pneumoniae strain DHQP1002001 plasmid p_IncFIB_DHQP1002001, complete sequence	299408-299437	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP014778	Pluralibacter gergoviae strain FB2 plasmid pFB2.3, complete sequence	118937-118966	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_MG462728	Escherichia coli strain AMA1416 plasmid pAMA1416, complete sequence	42431-42460	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	MN824000	Klebsiella pneumoniae strain 397108 plasmid p397108-FIIK, complete sequence	54406-54435	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	CP052489	Klebsiella pneumoniae strain C16KP0024 plasmid pC16KP0024-2, complete sequence	44641-44670	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_KY271406	Klebsiella pneumoniae strain H150820806 plasmid pKPN3-307_TypeC, complete sequence	138043-138072	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_KY495890	Klebsiella pneumoniae strain 301 plasmid pKP301cro, complete sequence	118853-118882	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_MF150084	Klebsiella pneumoniae strain A64477 plasmid pKP64477a, complete sequence	46759-46788	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_MG252894	Klebsiella pneumoniae strain Kpn-35963cz plasmid pKpn-35963cz, complete sequence	49975-50004	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP022923	Klebsiella pneumoniae strain ST307PT02 plasmid pJYC02A, complete sequence	9222-9251	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP033774	Klebsiella pneumoniae strain FDAARGOS_531 plasmid unnamed1, complete sequence	119680-119709	6	0.8
NC_020990_17	17.4|3218180|30|NC_020990|CRT	3218180-3218209	30	NZ_CP054304	Klebsiella pneumoniae strain MS14393 plasmid pMS14393A, complete sequence	161182-161211	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	748019-748048	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	349788-349817	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	7045-7074	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	KJ538722	Mycobacterium phage HH92, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	KT222940	Mycobacterium phage Kinbote, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	MH727549	Mycobacterium phage Gancho, complete genome	2273-2302	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	MK919482	Mycobacterium phage DeepSoil15, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	MT657330	Mycobacterium phage Webster2, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	MF919517	Mycobacterium phage LilHazelnut, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	EU203571	Mycobacterium phage Giles, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	MK494095	Mycobacterium phage Daegal, complete genome	2846-2875	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	MT818421	Mycobacterium phage Luke, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	MH697577	Mycobacterium phage Amochick, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	MT684594	Mycobacterium phage Hadrien, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	MT114159	Mycobacterium phage Ein37, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	KT246485	Mycobacterium phage OBUpride, complete genome	2567-2596	6	0.8
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	KT454972	Mycobacterium phage Evanesce, complete genome	2567-2596	6	0.8
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	NZ_CP011518	Pandoraea oxalativorans strain DSM 23570 plasmid pPO70-1, complete sequence	481561-481588	6	0.786
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	MH590600	Microbacterium phage KaiHaiDragon, complete genome	42151-42178	6	0.786
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	MK977698	Microbacterium phage Busephilis, complete genome	42166-42193	6	0.786
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	MK875798	Microbacterium phage Piperis, complete genome	42158-42185	6	0.786
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	MT818415	Microbacterium phage Scumberland, complete genome	42468-42495	6	0.786
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	MN444877	Microbacterium phage Antares, complete genome	42459-42486	6	0.786
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	560448-560475	6	0.786
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP046475	Janibacter melonis strain M714 plasmid unnamed, complete sequence	13740-13769	6	0.8
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP029051	Miniimonas sp. S16 plasmid pS16-2, complete sequence	26810-26839	6	0.8
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NC_021229	Arthrobacter nicotinovorans pAO1 megaplasmid sequence, strain ATCC 49919	126720-126749	6	0.8
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP016284	Cryobacterium arcticum strain PAMC 27867 plasmid pP27867_2, complete sequence	12620-12649	6	0.8
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP021994	Cryobacterium sp. LW097 plasmid unnamed1	51749-51778	6	0.8
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	765005-765034	6	0.8
NC_020990_24	24.3|4432142|30|NC_020990|CRISPRCasFinder	4432142-4432171	30	NZ_CP024896	Amycolatopsis sp. AA4 plasmid unnamed2, complete sequence	42498-42527	6	0.8
NC_020990_30	30.3|5367183|32|NC_020990|CRT	5367183-5367214	32	NC_009717	Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence	270524-270555	6	0.812
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	MG962371	Mycobacterium phage LaterM, complete genome	8333-8364	6	0.812
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	MF472892	Mycobacterium phage TreyKay, complete genome	8333-8364	6	0.812
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	KX641264	Mycobacterium phage LindNT, complete genome	8333-8364	6	0.812
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NC_014459	Mycobacterium virus CrimD, complete genome	8338-8369	6	0.812
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	KM677211	Mycobacterium phage Murucutumbu, complete genome	8326-8357	6	0.812
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	KX657796	Mycobacterium phage Urkel, complete genome	8317-8348	6	0.812
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	KX657794	Mycobacterium phage SamuelLPlaqson, complete genome	8317-8348	6	0.812
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	KX657795	Mycobacterium phage DrHayes, complete genome	8317-8348	6	0.812
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	MK016503	Mycobacterium phage Prithvi, complete genome	8333-8364	6	0.812
NC_020990_13	13.1|2718811|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718811-2718842	32	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	249518-249549	7	0.781
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5571122-5571153	7	0.781
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	NC_017805	Deinococcus gobiensis I-0 plasmid P1, complete sequence	138165-138196	7	0.781
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	MH588547	Caulobacter phage CcrSC, complete genome	250536-250567	7	0.781
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_017966	Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence	677145-677172	7	0.75
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_017966	Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence	678342-678369	7	0.75
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_CP009547	Burkholderia sp. 2002721687 plasmid pBTU, complete sequence	14998-15025	7	0.75
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_049851	Burkholderia phage BcepSauron, complete genome	52862-52889	7	0.75
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NC_049850	Burkholderia phage BcepSaruman, complete genome	52152-52179	7	0.75
NC_020990_16	16.3|3158598|28|NC_020990|CRISPRCasFinder	3158598-3158625	28	NZ_CP013381	Burkholderia sp. Bp5365 strain MSMB43 plasmid pMSMB43, complete sequence	102865-102892	7	0.75
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NZ_CP030830	Neorhizobium sp. NCHU2750 plasmid pNCHU2750c, complete sequence	317345-317374	7	0.767
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	MT657336	Microbacterium phage ClearAsMud, complete genome	42741-42768	7	0.75
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	MH533020	Acinetobacter phage ABPH49, complete genome	69644-69671	7	0.75
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	NC_047993	Microbacterium phage Quhwah, complete genome	42843-42870	7	0.75
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	MK737944	Microbacterium phage Warren, complete genome	10752-10779	7	0.75
NC_020990_18	18.1|3313901|28|NC_020990|PILER-CR	3313901-3313928	28	MH153799	Microbacterium phage Appa, complete genome	10554-10581	7	0.75
NC_020990_24	24.1|4432020|30|NC_020990|CRISPRCasFinder	4432020-4432049	30	NZ_AP018921	Pseudonocardia autotrophica strain NBRC 12743 plasmid pPA12743CP, complete sequence	74756-74785	7	0.767
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP033038	Agrobacterium fabrum strain 12D13 plasmid pAt12D13c, complete sequence	32846-32875	7	0.767
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP015237	Rhodococcus fascians D188 plasmid unnamed2, complete sequence	140989-141018	7	0.767
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	CP054924	Verrucosispora sp. NA02020 plasmid unnamed, complete sequence	24057-24086	7	0.767
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1042181-1042210	7	0.767
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NC_015409	Verrucosispora maris AB-18-032 plasmid pVMKU, complete sequence	52140-52169	7	0.767
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NC_034248	Rhizobium phage RHEph10, complete genome	50842-50871	7	0.767
NC_020990_24	24.3|4432142|30|NC_020990|CRISPRCasFinder	4432142-4432171	30	MN062717	Microbacterium phage Sharkboy, complete genome	34814-34843	7	0.767
NC_020990_24	24.3|4432142|30|NC_020990|CRISPRCasFinder	4432142-4432171	30	NC_042099	Microbacterium phage Dismas, complete genome	34724-34753	7	0.767
NC_020990_24	24.3|4432142|30|NC_020990|CRISPRCasFinder	4432142-4432171	30	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	116984-117013	7	0.767
NC_020990_24	24.3|4432142|30|NC_020990|CRISPRCasFinder	4432142-4432171	30	NC_004808	Streptomyces rochei plasmid pSLA2-L DNA, complete sequence	199341-199370	7	0.767
NC_020990_30	30.3|5367183|32|NC_020990|CRT	5367183-5367214	32	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	844082-844113	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	KX781992	Mycobacterium phage Gabriel, complete genome	14649-14680	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	MK359346	Mycobacterium phage NoodleTree, complete genome	15763-15794	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	JN699013	Mycobacterium phage Pio, complete genome	16624-16655	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	AY129337	Mycobacteriophage Bxz1, complete genome	16235-16266	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	MK112545	Mycobacterium phage Khaleesi, complete genome	15310-15341	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	MH825697	Mycobacterium phage Bangla1971, complete genome	15226-15257	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	MK359342	Mycobacterium phage ShiaLabeouf, complete genome	14853-14884	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NC_004687	Mycobacterium phage Bxz1, complete genome	16235-16266	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	MK359321	Mycobacterium phage Phusco, complete genome	15226-15257	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NC_029044	Mycobacterium phage Breeniome, complete genome	14658-14689	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	JN204348	Mycobacterium phage Sebata, complete genome	16342-16373	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP036181	Escherichia coli strain WCHEC025970 plasmid p2_025970, complete sequence	89266-89297	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_MG825377	Escherichia coli strain 1108 plasmid p1108-emrB, complete sequence	87777-87808	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	640270-640301	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	467346-467377	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	104255-104286	7	0.781
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	768044-768075	7	0.781
NC_020990_13	13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718933-2718964	32	NC_015314	Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence	182511-182542	8	0.75
NC_020990_13	13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718933-2718964	32	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	209667-209698	8	0.75
NC_020990_13	13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718933-2718964	32	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	477715-477746	8	0.75
NC_020990_13	13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718933-2718964	32	NC_023283	Streptomyces sp. FR1 plasmid pFRL3, complete sequence	160690-160721	8	0.75
NC_020990_13	13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718933-2718964	32	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	197318-197349	8	0.75
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	NZ_CP022424	Vitreoscilla filiformis strain ATCC 15551 plasmid pVF1, complete sequence	120863-120894	8	0.75
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	NZ_CP026518	Deinococcus sp. NW-56 plasmid unnamed2, complete sequence	155149-155180	8	0.75
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	133610-133639	8	0.733
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NC_011143	Phenylobacterium zucineum HLK1 plasmid, complete sequence	346711-346740	8	0.733
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NZ_CP040459	Pseudomonas stutzeri strain PheN2 plasmid unnamed, complete sequence	95555-95584	8	0.733
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NZ_LR134459	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence	71144-71173	8	0.733
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	718584-718613	8	0.733
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP013299	Arthrobacter sp. YC-RL1 plasmid unnamed 2, complete sequence	43900-43929	8	0.733
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP016082	Streptomyces sp. SAT1 plasmid unnamed2, complete sequence	193921-193950	8	0.733
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP017301	Rhodococcus sp. YL-1 plasmid pYLC2, complete sequence	10338-10367	8	0.733
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP050127	Rhodococcus erythropolis strain KB1 plasmid plas4, complete sequence	12455-12484	8	0.733
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP020556	Streptomyces sp. Sge12 plasmid pSGE, complete sequence	103587-103616	8	0.733
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP011869	Pseudonocardia sp. HH130629-09 plasmid pLS1-1, complete sequence	241575-241604	8	0.733
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NC_005284	Burkholderia phage phi1026b, complete genome	37058-37087	8	0.733
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	AY453853	Bacteriophage phi1026b, complete genome	37058-37087	8	0.733
NC_020990_24	24.3|4432142|30|NC_020990|CRISPRCasFinder	4432142-4432171	30	NZ_CP015446	Streptomyces sp. S8 plasmid unnamed, complete sequence	69345-69374	8	0.733
NC_020990_30	30.3|5367183|32|NC_020990|CRT	5367183-5367214	32	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	450059-450090	8	0.75
NC_020990_30	30.3|5367183|32|NC_020990|CRT	5367183-5367214	32	NC_013531	Xylanimonas cellulosilytica DSM 15894 plasmid pXCEL01, complete sequence	76871-76902	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP050093	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b5, complete sequence	309865-309896	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP050099	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b5, complete sequence	257175-257206	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP050105	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b6, complete sequence	474033-474064	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NC_008384	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence	473746-473777	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP025014	Rhizobium leguminosarum strain Norway plasmid pRLN2, complete sequence	394623-394654	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP053441	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eE, complete sequence	265982-266013	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP025508	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvB, complete sequence	379111-379142	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NC_012858	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132502, complete sequence	114407-114438	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP050110	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b4, complete sequence	474035-474066	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP022667	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR2, complete sequence	258535-258566	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP022566	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK02, complete sequence	486650-486681	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP050087	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b5, complete sequence	379098-379129	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	MT740732	Ralstonia phage Darius, complete genome	20470-20501	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	MT740740	Ralstonia phage Gervaise, complete genome	28911-28942	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	489152-489183	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	639923-639954	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	219240-219271	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP007144	Hymenobacter swuensis DY53 plasmid pHsw1, complete sequence	12122-12153	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	223374-223405	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP024423	Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence	176832-176863	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	205567-205598	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP035511	Haematobacter massiliensis strain OT1 plasmid pOT1-1, complete sequence	65547-65578	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	223374-223405	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	223383-223414	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	223401-223432	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	223373-223404	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	219259-219290	8	0.75
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP031079	Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence	160852-160883	8	0.75
NC_020990_30	30.5|5367305|32|NC_020990|CRT	5367305-5367336	32	NC_004934	Streptomyces violaceoruber strain SANK95570 plasmid pSV2, complete sequence	36190-36221	8	0.75
NC_020990_13	13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718872-2718903	32	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	341554-341585	9	0.719
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	574638-574669	9	0.719
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	1642455-1642486	9	0.719
NC_020990_16	16.1|3158476|37|NC_020990|CRISPRCasFinder	3158476-3158512	37	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	174719-174755	9	0.757
NC_020990_17	17.5|3218234|30|NC_020990|CRT	3218234-3218263	30	NZ_AP018829	Asticcacaulis excentricus strain M6 plasmid pASEM-1, complete sequence	120610-120639	9	0.7
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NC_023283	Streptomyces sp. FR1 plasmid pFRL3, complete sequence	125653-125682	9	0.7
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	162281-162310	9	0.7
NC_020990_24	24.2|4432081|30|NC_020990|CRISPRCasFinder	4432081-4432110	30	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1968988-1969017	9	0.7
NC_020990_30	30.3|5367183|32|NC_020990|CRT	5367183-5367214	32	NZ_CP041223	Porphyrobacter sp. YT40 plasmid pYT40, complete sequence	69891-69922	9	0.719
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP018230	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed2, complete sequence	82005-82036	9	0.719
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP030764	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed4, complete sequence	310542-310573	9	0.719
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP022417	Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-2, complete sequence	549-580	9	0.719
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	465939-465970	9	0.719
NC_020990_13	13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718872-2718903	32	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	151623-151654	10	0.688
NC_020990_13	13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718872-2718903	32	NC_008043	Ruegeria sp. TM1040 megaplasmid, complete sequence	141839-141870	10	0.688
NC_020990_13	13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718872-2718903	32	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	571414-571445	10	0.688
NC_020990_13	13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718872-2718903	32	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	302694-302725	10	0.688
NC_020990_13	13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718933-2718964	32	NZ_CP046574	Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence	439245-439276	10	0.688
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	NZ_CP029234	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436d, complete sequence	170177-170208	10	0.688
NC_020990_13	13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT	2718994-2719025	32	JQ015307	Pectobacterium phage phiTE, complete genome	805-836	10	0.688
NC_020990_30	30.3|5367183|32|NC_020990|CRT	5367183-5367214	32	NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	10970-11001	10	0.688
NC_020990_30	30.3|5367183|32|NC_020990|CRT	5367183-5367214	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	465140-465171	10	0.688
NC_020990_30	30.3|5367183|32|NC_020990|CRT	5367183-5367214	32	MK113951	Phage 5P_3, complete genome	34222-34253	10	0.688
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NC_015951	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI01, complete sequence	51764-51795	10	0.688
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP027023	Streptomyces sp. WAC00288 plasmid p1, complete sequence	2219-2250	10	0.688
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP027024	Streptomyces sp. WAC00288 plasmid p2, complete sequence	10861-10892	10	0.688
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP027026	Streptomyces sp. WAC00288 plasmid p4, complete sequence	13874-13905	10	0.688
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP043960	Streptomyces tendae strain 139 plasmid unnamed1, complete sequence	286226-286257	10	0.688
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NC_008043	Ruegeria sp. TM1040 megaplasmid, complete sequence	650158-650189	10	0.688
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP024150	Escherichia coli strain 14EC033 plasmid p14EC033c, complete sequence	31154-31185	11	0.656
NC_020990_30	30.4|5367244|32|NC_020990|CRT	5367244-5367275	32	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	574220-574251	11	0.656

1. spacer 3.8|1220850|27|NC_020990|PILER-CR matches to NC_013449 (Streptomyces sp. W9 plasmid pCQ3, complete sequence) position: , mismatch: 0, identity: 1.0

accggctgtgctgttgtagaggctgag	CRISPR spacer
accggctgtgctgttgtagaggctgag	Protospacer
***************************

2. spacer 15.1|2871420|21|NC_020990|PILER-CR matches to NZ_CP026518 (Deinococcus sp. NW-56 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.952

ggtgacgctcggccccaccgc	CRISPR spacer
ggtgacgctcggcaccaccgc	Protospacer
************* *******

3. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to NZ_AP014810 (Methylorubrum populi strain P-1M plasmid pMPPM01, complete sequence) position: , mismatch: 1, identity: 0.957

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgatggcctgcg	Protospacer
********************** 

4. spacer 3.3|1220844|36|NC_020990|CRISPRCasFinder matches to NC_013449 (Streptomyces sp. W9 plasmid pCQ3, complete sequence) position: , mismatch: 2, identity: 0.944

acaggcaccggctgtgctgttgtagaggctgaggag	CRISPR spacer
gtaggcaccggctgtgctgttgtagaggctgaggag	Protospacer
..**********************************

5. spacer 15.1|2871420|21|NC_020990|PILER-CR matches to NZ_CP047174 (Rathayibacter sp. VKM Ac-2760 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.905

ggtgacgctcggccccaccgc	CRISPR spacer
catgacgctcggccccaccgc	Protospacer
 .*******************

6. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to NZ_CP036181 (Escherichia coli strain WCHEC025970 plasmid p2_025970, complete sequence) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggttggcgatggccagct	Protospacer
******** ********** ***

7. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccagcagggcgatggcctgct	Protospacer
******  ***************

8. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccagcagggcgatggcctgct	Protospacer
******  ***************

9. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to NZ_MG825377 (Escherichia coli strain 1108 plasmid p1108-emrB, complete sequence) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggttggcgatggccagct	Protospacer
******** ********** ***

10. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to KX781992 (Mycobacterium phage Gabriel, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

11. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to MK359346 (Mycobacterium phage NoodleTree, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

12. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to JN699013 (Mycobacterium phage Pio, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

13. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to MT740732 (Ralstonia phage Darius, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
gcccaggtcggcgatggcctgct	Protospacer
* ****** **************

14. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to AY129337 (Mycobacteriophage Bxz1, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

15. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to MK112545 (Mycobacterium phage Khaleesi, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

16. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to MH825697 (Mycobacterium phage Bangla1971, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

17. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to MK359342 (Mycobacterium phage ShiaLabeouf, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

18. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to MT740740 (Ralstonia phage Gervaise, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
gcccaggtcggcgatggcctgct	Protospacer
* ****** **************

19. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to NC_004687 (Mycobacterium phage Bxz1, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

20. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to MK359321 (Mycobacterium phage Phusco, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

21. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to NC_029044 (Mycobacterium phage Breeniome, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

22. spacer 30.2|5367253|23|NC_020990|PILER-CR matches to JN204348 (Mycobacterium phage Sebata, complete genome) position: , mismatch: 2, identity: 0.913

ggccaggtgggcgatggcctgct	CRISPR spacer
ggccaggtgggcgaaggcctgtt	Protospacer
************** ******.*

23. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to MH155873 (Microbacterium phage Paschalis, complete genome) position: , mismatch: 3, identity: 0.893

-ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
actcg-gatgtttcacgtgaaacatccgt	Protospacer
 **** *.***************.*****

24. spacer 24.1|4432020|30|NC_020990|CRISPRCasFinder matches to NZ_CP023976 (Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence) position: , mismatch: 3, identity: 0.9

gatgatgttcgtgacgaccggagtggcctc	CRISPR spacer
aatgatgttggtgacgaccggggtggcctc	Protospacer
.******** ***********.********

25. spacer 30.1|5367192|23|NC_020990|PILER-CR matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 3, identity: 0.87

ggggtacgccatcaccgggcggc	CRISPR spacer
cggctacgccatcaccgggcgga	Protospacer
 ** ****************** 

26. spacer 32.3|6127816|25|NC_020990|CRISPRCasFinder matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 3, identity: 0.88

atcgtcctcatgccggacgggccgt	CRISPR spacer
atcgtcctcatgacgaacgggccgg	Protospacer
************ **.******** 

27. spacer 1.1|801289|29|NC_020990|CRISPRCasFinder matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 4, identity: 0.862

tcctggaccggcacggtgcaccggaaccg	CRISPR spacer
tcctcgaccggctcggtgcaccggaaacc	Protospacer
**** ******* ************* * 

28. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP025510 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence) position: , mismatch: 4, identity: 0.852

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
caacccgggctcgtcgaccagccgccc	Protospacer
* ******* ******* *******.*

29. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP025510 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence) position: , mismatch: 4, identity: 0.852

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
caacccgggctcgtcgaccagccgccc	Protospacer
* ******* ******* *******.*

30. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP025510 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence) position: , mismatch: 4, identity: 0.852

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
caacccgggctcgtcgaccagccgccc	Protospacer
* ******* ******* *******.*

31. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP025510 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence) position: , mismatch: 4, identity: 0.852

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
caacccgggctcgtcgaccagccgccc	Protospacer
* ******* ******* *******.*

32. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP025510 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence) position: , mismatch: 4, identity: 0.852

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
caacccgggctcgtcgaccagccgccc	Protospacer
* ******* ******* *******.*

33. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP025510 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence) position: , mismatch: 4, identity: 0.852

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
caacccgggctcgtcgaccagccgccc	Protospacer
* ******* ******* *******.*

34. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP025510 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence) position: , mismatch: 4, identity: 0.852

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
caacccgggctcgtcgaccagccgccc	Protospacer
* ******* ******* *******.*

35. spacer 17.5|3218234|30|NC_020990|CRT matches to NC_031255 (Gordonia phage Schwabeltier, complete genome) position: , mismatch: 4, identity: 0.867

ccaccgcggtcgtcgcgacggaaaccgccc-	CRISPR spacer
ccaccgcggtcgtcgcg-cgggaatcgcgct	Protospacer
***************** ***.**.*** * 

36. spacer 32.3|6127816|25|NC_020990|CRISPRCasFinder matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 4, identity: 0.84

atcgtcctcatgccggacgggccgt	CRISPR spacer
ttcgtccccatgccggacggaccgg	Protospacer
 ******.************.*** 

37. spacer 32.3|6127816|25|NC_020990|CRISPRCasFinder matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 4, identity: 0.84

atcgtcctcatgccggacgggccgt	CRISPR spacer
ttcgtccccatgccggacggaccgg	Protospacer
 ******.************.*** 

38. spacer 32.3|6127816|25|NC_020990|CRISPRCasFinder matches to NZ_AP022333 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence) position: , mismatch: 4, identity: 0.84

atcgtcctcatgccggacgggccgt	CRISPR spacer
gtcgtcctcaagccggacgggctct	Protospacer
.********* ***********. *

39. spacer 32.3|6127816|25|NC_020990|CRISPRCasFinder matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 4, identity: 0.84

atcgtcctcatgccggacgggccgt	CRISPR spacer
gtcgtcctcatgccgggcgcgccgg	Protospacer
.***************.** **** 

40. spacer 32.3|6127816|25|NC_020990|CRISPRCasFinder matches to NZ_CP036516 (Lichenihabitans psoromatis strain PAMC 29148 plasmid p_unnamed1, complete sequence) position: , mismatch: 4, identity: 0.84

atcgtcctcatgccggacgggccgt	CRISPR spacer
gtcgtcctcatgccggccgggacga	Protospacer
.*************** **** ** 

41. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP039925 (Agrobacterium tumefaciens strain CFBP7129 plasmid pAtCFBP7129b, complete sequence) position: , mismatch: 5, identity: 0.815

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
catcccggcgtcgtcgagcagccgcca	Protospacer
*  ***** ****************. 

42. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP031468 (Paraburkholderia caffeinilytica strain CF1 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.815

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
gcagccggggtcgtcaagcagccgcag	Protospacer
 ** ***********.*********  

43. spacer 3.8|1220850|27|NC_020990|PILER-CR matches to NZ_CP010187 (Escherichia coli strain M6 plasmid A, complete genome) position: , mismatch: 5, identity: 0.815

accggctgtgctgttgtagaggctgag	CRISPR spacer
tctggctgtgctgttgttgatgctgaa	Protospacer
 *.************** ** *****.

44. spacer 3.8|1220850|27|NC_020990|PILER-CR matches to NZ_CP010207 (Escherichia coli strain M11 plasmid A, complete sequence) position: , mismatch: 5, identity: 0.815

accggctgtgctgttgtagaggctgag	CRISPR spacer
tctggctgtgctgttgttgatgctgaa	Protospacer
 *.************** ** *****.

45. spacer 3.8|1220850|27|NC_020990|PILER-CR matches to NZ_CP010197 (Escherichia coli strain M9 plasmid A, complete genome) position: , mismatch: 5, identity: 0.815

accggctgtgctgttgtagaggctgag	CRISPR spacer
tctggctgtgctgttgttgatgctgaa	Protospacer
 *.************** ** *****.

46. spacer 3.8|1220850|27|NC_020990|PILER-CR matches to NZ_CP010222 (Escherichia coli strain M19 plasmid A, complete sequence) position: , mismatch: 5, identity: 0.815

accggctgtgctgttgtagaggctgag	CRISPR spacer
tctggctgtgctgttgttgatgctgaa	Protospacer
 *.************** ** *****.

47. spacer 3.8|1220850|27|NC_020990|PILER-CR matches to NZ_CP010214 (Escherichia coli strain M15 plasmid A, complete sequence) position: , mismatch: 5, identity: 0.815

accggctgtgctgttgtagaggctgag	CRISPR spacer
tctggctgtgctgttgttgatgctgaa	Protospacer
 *.************** ** *****.

48. spacer 16.1|3158476|37|NC_020990|CRISPRCasFinder matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 5, identity: 0.865

ttccggctcggcggcgggggttgaagacggtgaagtc	CRISPR spacer
ggaaggcgcggcggcgggggttgaagacggtgaagtc	Protospacer
    *** *****************************

49. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP007257 (Rhodococcus erythropolis R138 plasmid pLRE138, complete sequence) position: , mismatch: 5, identity: 0.833

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
cgccggccacggctcgtcgaggacgaggta	Protospacer
 .*  *****.*******************

50. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP045736 (Aeromicrobium sp. MF47 plasmid p001, complete sequence) position: , mismatch: 5, identity: 0.833

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
cgcgcgccacagctcgtccaggacgacgaa	Protospacer
 .**************** ******* * *

51. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NC_014549 (Glutamicibacter arilaitensis Re117 plasmid pRE117-1, complete sequence) position: , mismatch: 5, identity: 0.833

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
ggcacgccacagctcgtcgaggatgacgaa	Protospacer
*.*.*******************.** * *

52. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NC_008537 (Arthrobacter sp. FB24 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.833

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
ggcccgccacagctcgtccaggacgacgaa	Protospacer
*.* ************** ******* * *

53. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NC_009235 (Burkholderia phage phi644-2 chromosome, complete genome) position: , mismatch: 5, identity: 0.833

gacgcgcca---cagctcgtcgaggacgaggta	CRISPR spacer
---gcgctacagcagcgcgtcgaggacgaggta	Protospacer
   ****.*   **** ****************

54. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to CP000625 (Burkholderia phage phi644-2, complete genome) position: , mismatch: 5, identity: 0.833

gacgcgcca---cagctcgtcgaggacgaggta	CRISPR spacer
---gcgctacagcagcgcgtcgaggacgaggta	Protospacer
   ****.*   **** ****************

55. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to AF447491 (Bacteriophage phiE125, complete genome) position: , mismatch: 5, identity: 0.833

gacgcgcca---cagctcgtcgaggacgaggta	CRISPR spacer
---gcgctacagcagcgcgtcgaggacgaggta	Protospacer
   ****.*   **** ****************

56. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NC_003309 (Burkholderia phage phiE125, complete genome) position: , mismatch: 5, identity: 0.833

gacgcgcca---cagctcgtcgaggacgaggta	CRISPR spacer
---gcgctacagcagcgcgtcgaggacgaggta	Protospacer
   ****.*   **** ****************

57. spacer 1.1|801289|29|NC_020990|CRISPRCasFinder matches to NC_015057 (Granulicella tundricola MP5ACTX9 plasmid pACIX901, complete sequence) position: , mismatch: 6, identity: 0.793

tcctggaccggcacggtgcaccggaaccg	CRISPR spacer
acccccaccggcacggtgaaccggtaccg	Protospacer
 **.  ************ ***** ****

58. spacer 1.1|801289|29|NC_020990|CRISPRCasFinder matches to NZ_CP044073 (Pseudomonas oryzihabitans strain FDAARGOS_657 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

tcctggaccggcacggtgcaccggaaccg	CRISPR spacer
acctggaccggcacggggcacccggcgcg	Protospacer
 *************** ***** *.  **

59. spacer 3.6|1220844|41|NC_020990|CRT matches to NC_013449 (Streptomyces sp. W9 plasmid pCQ3, complete sequence) position: , mismatch: 6, identity: 0.854

acaggcaccggctgtgctgttgtagaggctgaggaggggtg	CRISPR spacer
gtaggcaccggctgtgctgttgtagaggctgaggaggttcc	Protospacer
..***********************************  . 

60. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 6, identity: 0.778

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
taggtcggggtcgtccagcagccgctc	Protospacer
. . .********** ***********

61. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP013072 (Sphingobium indicum B90A plasmid pSRL2, complete sequence) position: , mismatch: 6, identity: 0.778

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
ctgaccgggggcgtcgagcagccgccg	Protospacer
*.. ****** **************. 

62. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NC_008381 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL10, complete sequence) position: , mismatch: 6, identity: 0.778

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
gtttccggggtcgtcgaggtgccgctc	Protospacer
 . .**************  *******

63. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_LR699074 (Beijerinckiaceae bacterium RH AL1 isolate RH_AL1 plasmid 2) position: , mismatch: 6, identity: 0.778

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
gaacactgggtcgtcgagcagccgcca	Protospacer
  ** * ******************. 

64. spacer 3.7|1220789|27|NC_020990|PILER-CR matches to NZ_CP005190 (Sphingobium sp. MI1205 plasmid pMI1, complete sequence) position: , mismatch: 6, identity: 0.778

ccacccggggtcgtcgagcagccgctc	CRISPR spacer
ctgaccgggggcgtcgagcagccgccg	Protospacer
*.. ****** **************. 

65. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 6, identity: 0.812

tcgtcgagggtggcgttcaggaccgtgacgat--	CRISPR spacer
tcgtcgagggtggcgatcagggcctt--ccattc	Protospacer
*************** *****.** *  * **  

66. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 6, identity: 0.812

tcgtcgagggtggcgttcaggaccgtgacgat--	CRISPR spacer
tcgtcgagggtggcgatcagggcctt--ccattc	Protospacer
*************** *****.** *  * **  

67. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_KJ588780 (Achromobacter xylosoxidans strain A22732 plasmid pA22732-IMP, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

68. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_MN366359 (Bacterium plasmid pALTS31, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

69. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_001735 (Enterobacter aerogenes plasmid R751, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

70. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to AGRM01000006 (Salmonella enterica subsp. houtenae str. ATCC BAA-1581 plasmid pSEHO0A1, complete sequence, whole genome shotgun sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

71. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_017908 (Mycobacterium abscessus subsp. bolletii F1725 plasmid BRA100, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

72. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to AJ863570 (Uncultured bacterium IncP-1beta multiresistance plasmid pB8) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

73. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to KU238092 (Uncultured bacterium plasmid pDTC28, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

74. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JX469834 (Uncultured bacterium plasmid pDS3, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

75. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JX469831 (Uncultured bacterium plasmid pKSP212, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

76. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JN106172 (Uncultured bacterium plasmid pAKD29, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

77. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JN106173 (Uncultured bacterium plasmid pAKD31, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

78. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JN106174 (Uncultured bacterium plasmid pAKD33, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

79. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JN106164 (Uncultured bacterium plasmid pAKD1, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

80. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JN106165 (Uncultured bacterium plasmid pAKD14, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

81. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JN106166 (Uncultured bacterium plasmid pAKD15, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

82. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JN106168 (Uncultured bacterium plasmid pAKD17, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

83. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JN106169 (Uncultured bacterium plasmid pAKD18, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

84. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_014911 (Alicycliphilus denitrificans BC plasmid pALIDE02, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

85. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to MN386974 (Pseudomonas aeruginosa strain 1943 plasmid pPaeBURNS1, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

86. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
cctggcccacggactggccgaccgccgg	Protospacer
 .. ************* ********.*

87. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to MG879028 (Uncultured bacterium plasmid pEG1-1, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

88. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_CP021650 (Acidovorax sp. T1 plasmid p2-T1, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

89. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to KF743817 (Proteus mirabilis plasmid R772, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

90. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to KF743818 (Bordetella bronchiseptica plasmid R906, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

91. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to JX486125 (Uncultured bacterium plasmid pRWC72a, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

92. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_CP038640 (Cupriavidus oxalaticus strain X32 plasmid unnamed5, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

93. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to AJ639924 (Uncultured bacterium plasmid pB3 complete genome) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

94. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to KC170279 (Uncultured bacterium plasmid pMBUI8, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

95. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to KU356987 (Variovorax paradoxus plasmid pBS64, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

96. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to KU356988 (Variovorax paradoxus plasmid pHB44, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

97. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_CP009797 (Burkholderia ambifaria AMMD plasmid pBII_1, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

98. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_013176 (Pseudomonas putida plasmid pW2, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

99. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_019320 (Variovorax sp. DB1 plasmid pDB1, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

100. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_CP017455 (Dickeya solani strain PPO 9019 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

101. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_007337 (Cupriavidus pinatubonensis JMP134 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

102. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_MN366358 (Bacterium plasmid pALTS29, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

103. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_005088 (Delftia acidovorans B plasmid pUO1, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

104. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_CP018471 (Xanthomonas vesicatoria strain LM159 plasmid pLM159.2, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

105. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_KP289281 (Pseudomonas sp. EGD-AKN5 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

106. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_CP015373 (Pandoraea pnomenusa strain MCB032 plasmid unnamed 2, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

107. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_AP017604 (Sphingopyxis sp. EG6 plasmid pSREG01, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

108. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
cgcggcccacggcctgggcgaccgcctc	Protospacer
  * ******** *************  

109. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
cgcggcccacggcctgggcgaccgcctc	Protospacer
  * ******** *************  

110. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to AP018709 (Uncultured bacterium plasmid pSN1104-59 DNA, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

111. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_004956 (Pseudomonas sp. ADP atrazine catabolic plasmid pADP-1, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

112. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_CP019238 (Rhodoferax koreense strain DCY-110 plasmid unnamed2) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

113. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
cctggcccagggactgggcgaccgccgg	Protospacer
 .. ***** ****************.*

114. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_019312 (Delftia sp. KV29 plasmid pKV29, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

115. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_021077 (Comamonas sp. 7D-2 plasmid pBHB, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

116. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_024998 (Acidovorax avenae subsp. avenae plasmid pAAA83 DNA, complete sequence, strain: 83) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

117. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_MH053445 (Pseudomonas aeruginosa strain PA1280 plasmid pICP-4GES, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

118. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to AM157767 (Uncultured bacterium IncP-1gamma plasmid QKH54 complete genome) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

119. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_008385 (Burkholderia ambifaria AMMD plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

atccgcccacggactgggcgaccgccag	CRISPR spacer
tgccgcccacggcctgggcggccgcctc	Protospacer
  ********** *******.*****  

120. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052329 (Klebsiella pneumoniae strain D17KP0032 plasmid pD17KP0032-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

121. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_KY271405 (Klebsiella pneumoniae strain H151440672 plasmid pKPN3-307_typeB, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

122. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP025142 (Klebsiella pneumoniae strain KP1768 plasmid KP1768_p2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

123. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP026135 (Klebsiella pneumoniae strain F5 plasmid pF5_3, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

124. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018434 (Klebsiella pneumoniae strain MNCRE53 plasmid pMNCRE53_4, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

125. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP043049 (Klebsiella pneumoniae strain KLP268 plasmid pKLP268-3) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

126. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP040123 (Klebsiella pneumoniae strain LSH-KPN148 plasmid pLSH-KPN148-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

127. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP034282 (Klebsiella pneumoniae strain I72 plasmid p72_FIBkpn, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

128. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP050830 (Klebsiella pneumoniae strain Bckp067 plasmid pBckp067, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

129. spacer 17.4|3218180|30|NC_020990|CRT matches to NC_009649 (Klebsiella pneumoniae subsp. pneumoniae MGH 78578 plasmid pKPN3, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

130. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP011977 (Klebsiella pneumoniae DMC1097 plasmid pDMC1097-218.836kb, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

131. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP041928 (Klebsiella pneumoniae strain 18-2374 plasmid pSECR18-2374A, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

132. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP010393 (Klebsiella pneumoniae strain 34618 plasmid p34618-207.543kb, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

133. spacer 17.4|3218180|30|NC_020990|CRT matches to NC_022078 (Klebsiella pneumoniae JM45 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

134. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP027037 (Klebsiella pneumoniae strain 16_GR_13 plasmid IncFIB IncFII, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

135. spacer 17.4|3218180|30|NC_020990|CRT matches to NC_023332 (Klebsiella pneumoniae strain ST48 plasmid pKP09085, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

136. spacer 17.4|3218180|30|NC_020990|CRT matches to NC_023333 (Klebsiella pneumoniae strain ST23 plasmid pKP007, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

137. spacer 17.4|3218180|30|NC_020990|CRT matches to NC_023334 (Klebsiella pneumoniae strain ST15 plasmid pKP02022, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

138. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP020499 (Klebsiella pneumoniae strain BWHC1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

139. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP025038 (Klebsiella pneumoniae strain NU-CRE047 plasmid pNU-CRE047_1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

140. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018693 (Klebsiella pneumoniae strain Kp_Goe_821588 plasmid pKp_Goe_588-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

141. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP020855 (Klebsiella pneumoniae strain KPN528 plasmid pKPN528-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

142. spacer 17.4|3218180|30|NC_020990|CRT matches to LC549807 (Klebsiella pneumoniae VNCKp115 plasmid pVNCKp115 DNA, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

143. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP027054 (Klebsiella pneumoniae strain 2_GR_12 plasmid IncFIB IncFII) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

144. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP023479 (Klebsiella quasipneumoniae strain KPC142 plasmid pKQPS142a, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

145. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018424 (Klebsiella pneumoniae strain MNCRE69 plasmid pMNCRE69_4, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

146. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP029591 (Klebsiella pneumoniae strain DA33144 plasmid pDA33144-220, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

147. spacer 17.4|3218180|30|NC_020990|CRT matches to NC_021654 (Klebsiella pneumoniae plasmid pKN-LS6, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

148. spacer 17.4|3218180|30|NC_020990|CRT matches to NC_016966 (Klebsiella pneumoniae plasmid pUUH239.2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

149. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP042482 (Klebsiella pneumoniae strain C51 plasmid pC51_001, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

150. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP022920 (Klebsiella pneumoniae strain ST307PT03 plasmid pJYC03A, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

151. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP012572 (Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-6.X, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

152. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP029136 (Klebsiella pneumoniae strain AR376 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

153. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP014121 (Klebsiella pneumoniae strain FDAARGOS_156 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

154. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP041640 (Klebsiella pneumoniae strain PIMB15ND2KP27 plasmid pKP27-MPH, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

155. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP043854 (Enterobacter hormaechei strain EB_P6_L3_02.19 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

156. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP026752 (Klebsiella pneumoniae strain AR_0066 plasmid tig00000080_pilon, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

157. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052209 (Klebsiella pneumoniae strain E17KP0085 plasmid pE17KP0085-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

158. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP026179 (Klebsiella pneumoniae strain KPNIH49 plasmid pKPC-224e, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

159. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018355 (Klebsiella pneumoniae strain CAV1453 plasmid pCAV1453-208, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

160. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP031614 (Klebsiella pneumoniae strain ZYST1 plasmid pZYST1C1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

161. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_AP019689 (Klebsiella quasipneumoniae strain SNI47 plasmid pTMSNI47-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

162. spacer 17.4|3218180|30|NC_020990|CRT matches to LT009688 (Klebsiella pneumoniae plasmid pIT-06C07, strain O6CO7, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

163. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP009777 (Klebsiella pneumoniae subsp. pneumoniae strain KPNIH32 plasmid pKPN-a68, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

164. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP008800 (Klebsiella pneumoniae subsp. pneumoniae KPNIH24 plasmid pKPN-e44, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

165. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP046940 (Klebsiella pneumoniae strain BD_DM_697 plasmid punnamed1) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

166. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP006927 (Klebsiella pneumoniae 30660/NJST258_1 plasmid pNJST258N1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

167. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP008930 (Klebsiella pneumoniae strain PMK1 plasmid pPMK1-A, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

168. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP007729 (Klebsiella pneumoniae subsp. pneumoniae KPNIH10 plasmid pKPN-498, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

169. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP006663 (Klebsiella pneumoniae strain ATCC BAA-2146 plasmid pCuAs, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

170. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP029143 (Klebsiella michiganensis strain AR375 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

171. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP048380 (Klebsiella variicola strain 118 plasmid p118_A, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

172. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP020109 (Klebsiella pneumoniae strain AR_0098 plasmid tig00000001, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

173. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP020069 (Klebsiella pneumoniae strain AR_0068 plasmid unitig_2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

174. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP012567 (Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-6, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

175. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP036443 (Klebsiella pneumoniae strain ABFPV plasmid tig00001208_pilon, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

176. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP050379 (Klebsiella pneumoniae strain 51015 plasmid p51015_CTX_M_15, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

177. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP034130 (Klebsiella quasipneumoniae strain G4584 plasmid pG4584_218.9Kb, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

178. spacer 17.4|3218180|30|NC_020990|CRT matches to MF918373 (Klebsiella pneumoniae plasmid p1512-dfrA, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

179. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP050374 (Klebsiella pneumoniae strain 50595 plasmid p50595_NDM_1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

180. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP012884 (Klebsiella pneumoniae KP-1 plasmid pKP1-19, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

181. spacer 17.4|3218180|30|NC_020990|CRT matches to CP028804 (Klebsiella pneumoniae strain WCHKP7E2 plasmid pCMY2_085072, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

182. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP030343 (Klebsiella pneumoniae strain AR_362 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

183. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018460 (Klebsiella pneumoniae strain Kp_Goe_39795 plasmid pKp_Goe_795-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

184. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP020903 (Klebsiella pneumoniae strain K66-45 plasmid pK66-45-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

185. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP026212 (Citrobacter sp. CFNIH10 plasmid pCIT-a850, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

186. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP021856 (Klebsiella pneumoniae strain AR_0125 plasmid tig00000001_pilon, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

187. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP034138 (Klebsiella quasipneumoniae subsp. similipneumoniae strain G747 plasmid pG747_218.9Kb, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

188. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP027049 (Klebsiella pneumoniae strain 20_GR_12 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

189. spacer 17.4|3218180|30|NC_020990|CRT matches to MN823998 (Klebsiella pneumoniae strain 161116753 plasmid p116753-FIIK, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

190. spacer 17.4|3218180|30|NC_020990|CRT matches to MN823999 (Klebsiella pneumoniae strain 362713 plasmid p362713-FIIK, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

191. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP031809 (Klebsiella pneumoniae strain INF206-sc-2280074 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

192. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP032186 (Klebsiella pneumoniae strain AR_0075 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

193. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP027152 (Klebsiella pneumoniae strain AR_0363 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

194. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018365 (Klebsiella pneumoniae strain Kp_Goe_62629 plasmid pKp_Goe_629-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

195. spacer 17.4|3218180|30|NC_020990|CRT matches to NC_020132 (Klebsiella pneumoniae strain BK32179 plasmid pBK32179, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

196. spacer 17.4|3218180|30|NC_020990|CRT matches to NC_024992 (Klebsiella pneumoniae plasmid pKp848CTX, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

197. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP023947 (Klebsiella pneumoniae strain FDAARGOS_446 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

198. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP031369 (Klebsiella pneumoniae strain KpvST101_OXA-48 plasmid pKpvST101, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

199. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_AP014952 (Klebsiella oxytoca strain JKo3 plasmid pKO_JKo3_1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

200. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_LR025089 (Klebsiella pneumoniae isolate KP980 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

201. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP054265 (Klebsiella pneumoniae strain 39427 plasmid pKPN39427.1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

202. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP021951 (Klebsiella pneumoniae strain AR_0148 plasmid tig00000168_pilon, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

203. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP050823 (Klebsiella pneumoniae strain Bckp091 plasmid pBckp091-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

204. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP025145 (Klebsiella pneumoniae strain NR5632 plasmid NR5632_p2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

205. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP025148 (Klebsiella pneumoniae strain KP1766 plasmid KP1766_p2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

206. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP036188 (Klebsiella pneumoniae strain BA1559 plasmid pIncFIBK, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

207. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052469 (Klebsiella pneumoniae strain C16KP0053 plasmid pC16KP0053-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

208. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP015383 (Klebsiella pneumoniae strain CN1 plasmid pCN1_1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

209. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP023943 (Klebsiella pneumoniae strain FDAARGOS_444 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

210. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP027696 (Klebsiella pneumoniae strain KP30835 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

211. spacer 17.4|3218180|30|NC_020990|CRT matches to MN823997 (Klebsiella pneumoniae strain 111119051 plasmid p19051-FIIK, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

212. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP035536 (Klebsiella pneumoniae subsp. pneumoniae strain CCRI-22199 plasmid pKp199-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

213. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_KY271404 (Klebsiella pneumoniae strain Kp-48 plasmid pKPN3-307_typeA, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

214. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_MG288676 (Klebsiella pneumoniae strain F160070 plasmid p160070-catA, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

215. spacer 17.4|3218180|30|NC_020990|CRT matches to LR134219 (Klebsiella aerogenes strain NCTC10317 genome assembly, plasmid: 3) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

216. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018351 (Klebsiella pneumoniae strain CAV1417 plasmid pCAV1417-185, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

217. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018675 (Klebsiella pneumoniae strain CAV1217 plasmid pKPC_CAV1217, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

218. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052168 (Klebsiella pneumoniae strain F16KP0075 plasmid pF16KP0075-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

219. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP014073 (Klebsiella quasipneumoniae strain FDAARGOS_93 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

220. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_KX636095 (Klebsiella pneumoniae strain RJ119 plasmid pRJ119-NDM1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

221. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052485 (Klebsiella pneumoniae strain C16KP0036 plasmid pC16KP0036-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

222. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_KT203286 (Klebsiella pneumoniae strain U25 plasmid PU25001, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

223. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP021752 (Klebsiella pneumoniae strain AR_0113 plasmid unitig_1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

224. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP050844 (Klebsiella pneumoniae strain Bckp186 plasmid pBckp186, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

225. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP022125 (Klebsiella pneumoniae strain DHQP1605752_NV plasmid p1605752FIB, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

226. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018441 (Klebsiella pneumoniae strain Kp_Goe_822917 plasmid pKp_Goe_917-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

227. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP029588 (Klebsiella pneumoniae strain DA33141 plasmid pDA33141-217, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

228. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052408 (Klebsiella pneumoniae strain C17KP0008 plasmid pC17KP0008-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

229. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP035216 (Klebsiella michiganensis strain M82255 plasmid pKOCBH-B, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

230. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP014649 (Klebsiella pneumoniae strain KPNIH36 plasmid pKPN-fff, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

231. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP024193 (Klebsiella pneumoniae isolate KSB1_5D plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

232. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052401 (Klebsiella pneumoniae strain C17KP0039 plasmid pC17KP0039-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

233. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052572 (Klebsiella pneumoniae strain A16KP0016 plasmid pA16KP0016-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

234. spacer 17.4|3218180|30|NC_020990|CRT matches to MN543573 (Klebsiella pneumoniae strain GH44 plasmid pGH44_216, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

235. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP028954 (Klebsiella pneumoniae strain AR_0141 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

236. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP033627 (Klebsiella pneumoniae strain 4743 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

237. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP036302 (Klebsiella pneumoniae subsp. pneumoniae strain WCHKP015093 plasmid p1_015093, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

238. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_LR130542 (Klebsiella pneumoniae strain AJ218 isolate AJ218 plasmid 2) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

239. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052405 (Klebsiella pneumoniae strain C17KP0020 plasmid pC17KP0020-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

240. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP020842 (Klebsiella pneumoniae strain KPN1482 plasmid pKPN1482-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

241. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP031811 (Klebsiella pneumoniae strain INF014-sc-2279884 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

242. spacer 17.4|3218180|30|NC_020990|CRT matches to MN891675 (Klebsiella pneumoniae strain 358573 plasmid p358573-KPC, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

243. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP020838 (Klebsiella pneumoniae strain BK13043 plasmid pBK13043-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

244. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP028784 (Klebsiella pneumoniae strain SCKP020049 plasmid p1_020049, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

245. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052218 (Klebsiella pneumoniae strain E17KP0053 plasmid pE17KP0053-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

246. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP031735 (Klebsiella pneumoniae subsp. pneumoniae strain Klebsiella pneumoniae plasmid pKPM501, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

247. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018818 (Klebsiella pneumoniae strain AR_0049 plasmid unitig_2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

248. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP037966 (Klebsiella pneumoniae strain SCKP020135 plasmid p1_020135, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

249. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052148 (Klebsiella pneumoniae strain F16KP0108 plasmid pF16KP0108-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

250. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP041084 (Klebsiella pneumoniae strain Kp202 plasmid pKp202_2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

251. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP036337 (Klebsiella pneumoniae strain BP327 plasmid pIncFIBK, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

252. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052415 (Klebsiella pneumoniae strain C16KP0189 plasmid pC16KP0189-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

253. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052559 (Klebsiella pneumoniae strain A17KP0008 plasmid pA17KP0008-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

254. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052270 (Klebsiella pneumoniae strain E16KP0268 plasmid pE16K0268-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

255. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP041514 (Klebsiella michiganensis strain KNU07 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

256. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP041100 (Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH07 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

257. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP021834 (Klebsiella pneumoniae strain AR_0120 plasmid tig00000500_pilon, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

258. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP022692 (Klebsiella pneumoniae subsp. pneumoniae strain AUSMDU00008079 plasmid pAUSMDU00008079_01, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

259. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP035180 (Klebsiella pneumoniae strain BA33875 plasmid pBA33875_IncFIB, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

260. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP015132 (Klebsiella pneumoniae strain Kpn555 plasmid pKPN-d90, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

261. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP018886 (Klebsiella pneumoniae subsp. pneumoniae strain BR21 plasmid pIncF, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

262. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP039809 (Klebsiella pneumoniae strain C2660 plasmid pC2660-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

263. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP029101 (Klebsiella pneumoniae strain AR438 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

264. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP040025 (Klebsiella pneumoniae strain KPC160132 plasmid pKpn3-L132, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

265. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052561 (Klebsiella pneumoniae strain A17KP0004 plasmid pA17KP0004-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

266. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP028995 (Klebsiella pneumoniae strain AR_0079 plasmid unnamed6, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

267. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP033402 (Klebsiella pneumoniae strain WCHKP115069 plasmid p1_115069, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

268. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP031583 (Klebsiella pneumoniae strain N4b plasmid pIncFII-1502320, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

269. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP029598 (Klebsiella quasipneumoniae subsp. similipneumoniae strain ATCC 700603 plasmid pDA33145-152, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

270. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP047337 (Klebsiella pneumoniae strain 2019036D plasmid p2019036D-mcr8-345kb, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

271. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP021544 (Klebsiella pneumoniae strain AR_0112 plasmid tig00000000, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

272. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP021540 (Klebsiella pneumoniae strain AR_0047 plasmid tig00000001, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

273. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP021686 (Klebsiella pneumoniae strain AR_0146 plasmid tig00001160, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

274. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP022926 (Klebsiella pneumoniae strain ST307PT01 plasmid pJYC01A, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

275. spacer 17.4|3218180|30|NC_020990|CRT matches to KT896504 (Klebsiella pneumoniae strain I11 plasmid pKPSH11, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

276. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP009879 (Klebsiella pneumoniae subsp. pneumoniae strain KPNIH31 plasmid pKPN-c22, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

277. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP046950 (Klebsiella pneumoniae strain BD_DM_914 plasmid punnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

278. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052288 (Klebsiella pneumoniae strain E16KP0218 plasmid pE16KP0218-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

279. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP022824 (Klebsiella quasivariicola strain KPN1705 plasmid pKPN1705-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

280. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP020072 (Klebsiella pneumoniae strain AR_0115 plasmid tig00000002, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

281. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP015386 (Klebsiella pneumoniae strain NY9 plasmid pNY9_1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

282. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP024537 (Klebsiella pneumoniae strain KSB1_9D plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

283. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP024516 (Klebsiella pneumoniae strain KSB1_10J plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

284. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052276 (Klebsiella pneumoniae strain E16KP0241 plasmid pE16KP0241-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

285. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052298 (Klebsiella pneumoniae strain E16KP0204 plasmid pE16KP0204-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

286. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_LR130549 (Klebsiella pneumoniae strain KPC2 isolate KPC2 plasmid 2) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

287. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP046382 (Klebsiella pneumoniae strain BD_DM_782 plasmid punnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

288. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP022574 (Klebsiella pneumoniae strain BIC-1 plasmid pBIC-1a, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

289. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052387 (Klebsiella pneumoniae strain C17KP0055 plasmid pC17KP0055-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

290. spacer 17.4|3218180|30|NC_020990|CRT matches to NC_021198 (Klebsiella pneumoniae subsp. pneumoniae KPX plasmid pKPX-1 DNA, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

291. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP021713 (Klebsiella pneumoniae strain AR_0129 plasmid tig00000000, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

292. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP026151 (Klebsiella pneumoniae strain F138 plasmid pF138_2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

293. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP040030 (Klebsiella pneumoniae strain KPC160121 plasmid pQnr-L121, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

294. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052538 (Klebsiella pneumoniae strain B16KP0141 plasmid pB16KP0141-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

295. spacer 17.4|3218180|30|NC_020990|CRT matches to MF116002 (Uncultured bacterium plasmid pLGP4 clone J53, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

296. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP029387 (Klebsiella pneumoniae subsp. pneumoniae strain SCKP040074 plasmid pTetD_040074, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

297. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP028181 (Klebsiella pneumoniae strain CFSAN054110 plasmid pGMI16-005_01, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

298. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052441 (Klebsiella pneumoniae strain C16KP0102 plasmid pC16KP0102-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

299. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_LR025093 (Klebsiella pneumoniae isolate KP9201 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

300. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP024500 (Klebsiella pneumoniae strain KSB1_4E plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

301. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP029724 (Klebsiella pneumoniae strain AR_0140 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

302. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052370 (Klebsiella pneumoniae strain D16KP0087 plasmid pD16KP0087-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

303. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP024508 (Klebsiella pneumoniae strain KSB2_1B plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

304. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP024551 (Klebsiella pneumoniae strain INF163 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

305. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP032209 (Klebsiella pneumoniae strain AR_0109 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

306. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP014697 (Klebsiella quasipneumoniae strain ATCC 700603 isolate K6 plasmid pKQPS1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

307. spacer 17.4|3218180|30|NC_020990|CRT matches to MN842293 (Klebsiella pneumoniae strain 20130907-4 plasmid p309074-1FIIK, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

308. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052506 (Klebsiella pneumoniae strain B16KP0226 plasmid pB16KP0226-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

309. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052214 (Klebsiella pneumoniae strain E17KP0079 plasmid pE17KP0079-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

310. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP015823 (Klebsiella pneumoniae isolate blood sample 2 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

311. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP021710 (Klebsiella pneumoniae strain AR_0143 plasmid tig00000853, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

312. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP023488 (Klebsiella pneumoniae subsp. pneumoniae strain ST101:960186733 plasmid p19-10_01, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

313. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052263 (Klebsiella pneumoniae strain E16KP0288 plasmid pE16K0288-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

314. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP027161 (Klebsiella pneumoniae strain AR_0361 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

315. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP025009 (Klebsiella pneumoniae strain AUSMDU00008119 plasmid pAUSMDU8119-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

316. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP022917 (Klebsiella pneumoniae strain ST307PT04 plasmid pJYC04A, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

317. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052237 (Klebsiella pneumoniae strain E17KP0029 plasmid pE17KP0029-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

318. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP042883 (Klebsiella pneumoniae strain NMBU-W07E18 plasmid pNMBU-W07E18_01, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

319. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052435 (Klebsiella pneumoniae strain C16KP0108 plasmid pC16KP0108-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

320. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052140 (Klebsiella pneumoniae strain F17KP0040 plasmid pF17KP0040-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

321. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP035211 (Klebsiella pneumoniae strain TH164 plasmid pTH164-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

322. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052499 (Klebsiella pneumoniae strain B17KP0021 plasmid pB17KP0021-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

323. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP028543 (Klebsiella pneumoniae subsp. pneumoniae strain SCKP020143 plasmid p1_020143, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

324. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP024483 (Klebsiella pneumoniae strain INF322 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

325. spacer 17.4|3218180|30|NC_020990|CRT matches to CP028781 (Klebsiella pneumoniae subsp. pneumoniae strain SCKP020046 plasmid pNDM5_020046, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

326. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP027425 (Klebsiella oxytoca strain FDAARGOS_335 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

327. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052477 (Klebsiella pneumoniae strain C16KP0050 plasmid pC16KP0050-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

328. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP025006 (Klebsiella pneumoniae strain AUSMDU00003562 plasmid pAUSMDU3562-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

329. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP026716 (Klebsiella oxytoca strain AR_0028 plasmid unitig_1_pilon, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

330. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052243 (Klebsiella pneumoniae strain E17KP0019 plasmid pE17KP0019-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

331. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP030071 (Klebsiella pneumoniae strain DA12090 plasmid pDA12090.1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

332. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP037929 (Klebsiella pneumoniae subsp. pneumoniae strain KP-8788 plasmid pKPN-IT-8788, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

333. spacer 17.4|3218180|30|NC_020990|CRT matches to MN922301 (Klebsiella pneumoniae strain KP-14159 plasmid pKPN-IT-14159, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

334. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_LT994840 (Klebsiella pneumoniae isolate CNR48 plasmid CNR48, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

335. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP015393 (Klebsiella pneumoniae strain CR14 plasmid pCR14_1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

336. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052337 (Klebsiella pneumoniae strain D17KP0018 plasmid pD17KP0018-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

337. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052307 (Klebsiella pneumoniae strain E16KP0133 plasmid pE16KP0133-1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

338. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_LR130540 (Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

339. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_MN268580 (Klebsiella pneumoniae strain KP13-53 plasmid pKP13-53-tet(A), complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

340. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_MH745929 (Klebsiella pneumoniae strain VRES1611 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

341. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP016810 (Klebsiella pneumoniae strain DHQP1002001 plasmid p_IncFIB_DHQP1002001, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

342. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP014778 (Pluralibacter gergoviae strain FB2 plasmid pFB2.3, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

343. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_MG462728 (Escherichia coli strain AMA1416 plasmid pAMA1416, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

344. spacer 17.4|3218180|30|NC_020990|CRT matches to MN824000 (Klebsiella pneumoniae strain 397108 plasmid p397108-FIIK, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

345. spacer 17.4|3218180|30|NC_020990|CRT matches to CP052489 (Klebsiella pneumoniae strain C16KP0024 plasmid pC16KP0024-2, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

346. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_KY271406 (Klebsiella pneumoniae strain H150820806 plasmid pKPN3-307_TypeC, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

347. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_KY495890 (Klebsiella pneumoniae strain 301 plasmid pKP301cro, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

348. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_MF150084 (Klebsiella pneumoniae strain A64477 plasmid pKP64477a, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

349. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_MG252894 (Klebsiella pneumoniae strain Kpn-35963cz plasmid pKpn-35963cz, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

350. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP022923 (Klebsiella pneumoniae strain ST307PT02 plasmid pJYC02A, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

351. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP033774 (Klebsiella pneumoniae strain FDAARGOS_531 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

352. spacer 17.4|3218180|30|NC_020990|CRT matches to NZ_CP054304 (Klebsiella pneumoniae strain MS14393 plasmid pMS14393A, complete sequence) position: , mismatch: 6, identity: 0.8

tcccga--cggaagccaccctcacgacggtca	CRISPR spacer
--cggatccgggagccacgctcacgacggtcg	Protospacer
  * **  ***.****** ************.

353. spacer 17.5|3218234|30|NC_020990|CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
cttccgcggtcgtcgccacggaaaccacgg	Protospacer
*. ************* *********.*  

354. spacer 17.5|3218234|30|NC_020990|CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
cttccgcggtcgtcgccacggaaaccacgg	Protospacer
*. ************* *********.*  

355. spacer 17.5|3218234|30|NC_020990|CRT matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
cttccgcggtcgtcgccacggaaaccacgg	Protospacer
*. ************* *********.*  

356. spacer 17.5|3218234|30|NC_020990|CRT matches to KJ538722 (Mycobacterium phage HH92, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

357. spacer 17.5|3218234|30|NC_020990|CRT matches to KT222940 (Mycobacterium phage Kinbote, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

358. spacer 17.5|3218234|30|NC_020990|CRT matches to MH727549 (Mycobacterium phage Gancho, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

359. spacer 17.5|3218234|30|NC_020990|CRT matches to MK919482 (Mycobacterium phage DeepSoil15, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

360. spacer 17.5|3218234|30|NC_020990|CRT matches to MT657330 (Mycobacterium phage Webster2, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

361. spacer 17.5|3218234|30|NC_020990|CRT matches to MF919517 (Mycobacterium phage LilHazelnut, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

362. spacer 17.5|3218234|30|NC_020990|CRT matches to EU203571 (Mycobacterium phage Giles, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

363. spacer 17.5|3218234|30|NC_020990|CRT matches to MK494095 (Mycobacterium phage Daegal, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

364. spacer 17.5|3218234|30|NC_020990|CRT matches to MT818421 (Mycobacterium phage Luke, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

365. spacer 17.5|3218234|30|NC_020990|CRT matches to MH697577 (Mycobacterium phage Amochick, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

366. spacer 17.5|3218234|30|NC_020990|CRT matches to MT684594 (Mycobacterium phage Hadrien, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

367. spacer 17.5|3218234|30|NC_020990|CRT matches to MT114159 (Mycobacterium phage Ein37, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

368. spacer 17.5|3218234|30|NC_020990|CRT matches to KT246485 (Mycobacterium phage OBUpride, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

369. spacer 17.5|3218234|30|NC_020990|CRT matches to KT454972 (Mycobacterium phage Evanesce, complete genome) position: , mismatch: 6, identity: 0.8

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccaccgcggccgtcgcgtcggaacaccccg	Protospacer
*********.******* *****  * ** 

370. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to NZ_CP011518 (Pandoraea oxalativorans strain DSM 23570 plasmid pPO70-1, complete sequence) position: , mismatch: 6, identity: 0.786

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
gtatcggtgtttaacgtgaaacgtccgc	Protospacer
 *  .******* **************.

371. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to MH590600 (Microbacterium phage KaiHaiDragon, complete genome) position: , mismatch: 6, identity: 0.786

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
actctgatgtttcacgtgaaacatccgt	Protospacer
 .. **.***************.*****

372. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to MK977698 (Microbacterium phage Busephilis, complete genome) position: , mismatch: 6, identity: 0.786

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
actctgatgtttcacgtgaaacatccgt	Protospacer
 .. **.***************.*****

373. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to MK875798 (Microbacterium phage Piperis, complete genome) position: , mismatch: 6, identity: 0.786

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
actctgatgtttcacgtgaaacatccgt	Protospacer
 .. **.***************.*****

374. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to MT818415 (Microbacterium phage Scumberland, complete genome) position: , mismatch: 6, identity: 0.786

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
actctgatgtttcacgtgaaacatccgt	Protospacer
 .. **.***************.*****

375. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to MN444877 (Microbacterium phage Antares, complete genome) position: , mismatch: 6, identity: 0.786

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
actctgatgtttcacgtgaaacatccgt	Protospacer
 .. **.***************.*****

376. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 6, identity: 0.786

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
tttgtggtgtttcaggtgaaacgttttt	Protospacer
.*.*********** *********.. *

377. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP046475 (Janibacter melonis strain M714 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
cacgcgccacagctcgtccatgacgagcac	Protospacer
 ***************** * ******   

378. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP029051 (Miniimonas sp. S16 plasmid pS16-2, complete sequence) position: , mismatch: 6, identity: 0.8

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
cgcgcgccacagctcgtcgaggatcacgaa	Protospacer
 .*********************. * * *

379. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NC_021229 (Arthrobacter nicotinovorans pAO1 megaplasmid sequence, strain ATCC 49919) position: , mismatch: 6, identity: 0.8

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
agcacgccacagctcgtccaggacgacgaa	Protospacer
..*.************** ******* * *

380. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP016284 (Cryobacterium arcticum strain PAMC 27867 plasmid pP27867_2, complete sequence) position: , mismatch: 6, identity: 0.8

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
ggctcgccagagctcgtcgaggacgacgag	Protospacer
*.* ***** **************** * .

381. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP021994 (Cryobacterium sp. LW097 plasmid unnamed1) position: , mismatch: 6, identity: 0.8

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
cgcccgccacagctcgtcgaggatgacgaa	Protospacer
 .* *******************.** * *

382. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
gccgatccacagctcgccggggacgaggtc	Protospacer
* **  **********.**.********* 

383. spacer 24.3|4432142|30|NC_020990|CRISPRCasFinder matches to NZ_CP024896 (Amycolatopsis sp. AA4 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

gccgaccagccacacccgccggtgcgggag-	CRISPR spacer
gccgaccagccacacccggc-gcgtggccgc	Protospacer
****************** * *.*.**  * 

384. spacer 30.3|5367183|32|NC_020990|CRT matches to NC_009717 (Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence) position: , mismatch: 6, identity: 0.812

gaggggtacgccatcaccgggcggccgccggc	CRISPR spacer
gaggtcatcgcgatcaccggggggccgccggc	Protospacer
****    *** ********* **********

385. spacer 30.4|5367244|32|NC_020990|CRT matches to MG962371 (Mycobacterium phage LaterM, complete genome) position: , mismatch: 6, identity: 0.812

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccggaaacgtgggcgatggcctgcccggcgtc	Protospacer
* **  * ****************.**.****

386. spacer 30.4|5367244|32|NC_020990|CRT matches to MF472892 (Mycobacterium phage TreyKay, complete genome) position: , mismatch: 6, identity: 0.812

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccggaaacgtgggcgatggcctgcccggcgtc	Protospacer
* **  * ****************.**.****

387. spacer 30.4|5367244|32|NC_020990|CRT matches to KX641264 (Mycobacterium phage LindNT, complete genome) position: , mismatch: 6, identity: 0.812

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccggaaacgtgggcgatggcctgcccggcgtc	Protospacer
* **  * ****************.**.****

388. spacer 30.4|5367244|32|NC_020990|CRT matches to NC_014459 (Mycobacterium virus CrimD, complete genome) position: , mismatch: 6, identity: 0.812

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccggagacgtgggcgatggcctgcccggcgtc	Protospacer
* **  * ****************.**.****

389. spacer 30.4|5367244|32|NC_020990|CRT matches to KM677211 (Mycobacterium phage Murucutumbu, complete genome) position: , mismatch: 6, identity: 0.812

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccggaaacgtgggcgatggcctgcccggcgtc	Protospacer
* **  * ****************.**.****

390. spacer 30.4|5367244|32|NC_020990|CRT matches to KX657796 (Mycobacterium phage Urkel, complete genome) position: , mismatch: 6, identity: 0.812

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccgccaacgtgggcgatggcctgcccggcgtc	Protospacer
* * * * ****************.**.****

391. spacer 30.4|5367244|32|NC_020990|CRT matches to KX657794 (Mycobacterium phage SamuelLPlaqson, complete genome) position: , mismatch: 6, identity: 0.812

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccgccaacgtgggcgatggcctgcccggcgtc	Protospacer
* * * * ****************.**.****

392. spacer 30.4|5367244|32|NC_020990|CRT matches to KX657795 (Mycobacterium phage DrHayes, complete genome) position: , mismatch: 6, identity: 0.812

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccgccaacgtgggcgatggcctgcccggcgtc	Protospacer
* * * * ****************.**.****

393. spacer 30.4|5367244|32|NC_020990|CRT matches to MK016503 (Mycobacterium phage Prithvi, complete genome) position: , mismatch: 6, identity: 0.812

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccggaaacgtgggcgatggcctgcccggcgtc	Protospacer
* **  * ****************.**.****

394. spacer 13.1|2718811|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 7, identity: 0.781

agttggcaccgccgcacgatgatcacaaccca	CRISPR spacer
acgtgggaccgcggcacgatgatcaccgccga	Protospacer
*  *** ***** ************* .** *

395. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.781

tcgtcgagggtggcgttcaggaccgtgacgat	CRISPR spacer
tggtcgagggtggcgtccagcaccgcgcggtt	Protospacer
* **************.*** ****.*  * *

396. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NC_017805 (Deinococcus gobiensis I-0 plasmid P1, complete sequence) position: , mismatch: 7, identity: 0.781

tcgtcgagggtggcgttcaggaccgtgacgat-	CRISPR spacer
atggcgtgggtggcgttctggaccgtg-cggta	Protospacer
 .* ** *********** ******** **.* 

397. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to MH588547 (Caulobacter phage CcrSC, complete genome) position: , mismatch: 7, identity: 0.781

tcgtcgagggtggcgttcaggaccgtgacgat-	CRISPR spacer
tcgtcgcgggtggcgtccagga-cgtgcttgtg	Protospacer
****** *********.***** **** . .* 

398. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_017966 (Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence) position: , mismatch: 7, identity: 0.75

atccgcccacggactgggcgaccgccag	CRISPR spacer
cgccgcccaccgactgtgcgaccgcgcc	Protospacer
  ******** ***** ********   

399. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_017966 (Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence) position: , mismatch: 7, identity: 0.75

atccgcccacggactgggcgaccgccag	CRISPR spacer
cgccgcccaccgactgggcgatcgcgcc	Protospacer
  ******** **********.***   

400. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_CP009547 (Burkholderia sp. 2002721687 plasmid pBTU, complete sequence) position: , mismatch: 7, identity: 0.75

atccgcccacggactgggcgaccgccag	CRISPR spacer
tcgtgcccgcggactggtcgaccgccac	Protospacer
 . .****.******** ********* 

401. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_049851 (Burkholderia phage BcepSauron, complete genome) position: , mismatch: 7, identity: 0.75

atccgcccacggactgggcgaccgccag	CRISPR spacer
tcgagaccacggactgggcgaccaccat	Protospacer
 .  * *****************.*** 

402. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NC_049850 (Burkholderia phage BcepSaruman, complete genome) position: , mismatch: 7, identity: 0.75

atccgcccacggactgggcgaccgccag	CRISPR spacer
tcgagaccacggactgggcgaccaccat	Protospacer
 .  * *****************.*** 

403. spacer 16.3|3158598|28|NC_020990|CRISPRCasFinder matches to NZ_CP013381 (Burkholderia sp. Bp5365 strain MSMB43 plasmid pMSMB43, complete sequence) position: , mismatch: 7, identity: 0.75

atccgcccacggactgggcgaccgccag	CRISPR spacer
tcgtgcccgcggactggtcgaccgccac	Protospacer
 . .****.******** ********* 

404. spacer 17.5|3218234|30|NC_020990|CRT matches to NZ_CP030830 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750c, complete sequence) position: , mismatch: 7, identity: 0.767

--ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
agccgc--cggtcgtcgcgccggaaaccgatg	Protospacer
  **.*  *********** ********* . 

405. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to MT657336 (Microbacterium phage ClearAsMud, complete genome) position: , mismatch: 7, identity: 0.75

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
aggccgatgtttcacgtgaaacatccgt	Protospacer
    .*.***************.*****

406. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to MH533020 (Acinetobacter phage ABPH49, complete genome) position: , mismatch: 7, identity: 0.75

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
ttcgtggtgtttcacggcaaacgtgtaa	Protospacer
.***************  ****** .. 

407. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to NC_047993 (Microbacterium phage Quhwah, complete genome) position: , mismatch: 7, identity: 0.75

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
actccgatgtttcacgtgaaacatccgt	Protospacer
 .. .*.***************.*****

408. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to MK737944 (Microbacterium phage Warren, complete genome) position: , mismatch: 7, identity: 0.75

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
ctcctgatgtttcacgtgaaacgctgag	Protospacer
*** **.****************.. . 

409. spacer 18.1|3313901|28|NC_020990|PILER-CR matches to MH153799 (Microbacterium phage Appa, complete genome) position: , mismatch: 7, identity: 0.75

ctcgtggtgtttcacgtgaaacgtccgt	CRISPR spacer
ctcctgatgtttcacgtgaaacgctgag	Protospacer
*** **.****************.. . 

410. spacer 24.1|4432020|30|NC_020990|CRISPRCasFinder matches to NZ_AP018921 (Pseudonocardia autotrophica strain NBRC 12743 plasmid pPA12743CP, complete sequence) position: , mismatch: 7, identity: 0.767

gatgatgttcgtgacgaccggagtggcctc	CRISPR spacer
gatgacgttcgtgacgaccgggcgcccctg	Protospacer
*****.***************.    *** 

411. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP033038 (Agrobacterium fabrum strain 12D13 plasmid pAt12D13c, complete sequence) position: , mismatch: 7, identity: 0.767

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
tccgcgcgacagctcgtcgaggaccgcgaa	Protospacer
  ***** **************** . * *

412. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP015237 (Rhodococcus fascians D188 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
gtcgcggcacagctcgtcgaggtcgtagcc	Protospacer
* **** *************** ** .*. 

413. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to CP054924 (Verrucosispora sp. NA02020 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
cgcccgccacagctcgtcgagcacggtgaa	Protospacer
 .* ***************** ***. * *

414. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 7, identity: 0.767

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
gtcgcgccacagctcgtccaggtcgggcgg	Protospacer
* **************** *** **.*  .

415. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NC_015409 (Verrucosispora maris AB-18-032 plasmid pVMKU, complete sequence) position: , mismatch: 7, identity: 0.767

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
cgcccgccacagctcgtcgagcacggtgaa	Protospacer
 .* ***************** ***. * *

416. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NC_034248 (Rhizobium phage RHEph10, complete genome) position: , mismatch: 7, identity: 0.767

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
ggcgcgcaacagctcgtcgaggataatctg	Protospacer
*.***** ***************..*  *.

417. spacer 24.3|4432142|30|NC_020990|CRISPRCasFinder matches to MN062717 (Microbacterium phage Sharkboy, complete genome) position: , mismatch: 7, identity: 0.767

gccgaccagccacacccgccggtgcgggag	CRISPR spacer
cacccgcagccgcacccggcggtgcgggag	Protospacer
  *   *****.****** ***********

418. spacer 24.3|4432142|30|NC_020990|CRISPRCasFinder matches to NC_042099 (Microbacterium phage Dismas, complete genome) position: , mismatch: 7, identity: 0.767

gccgaccagccacacccgccggtgcgggag	CRISPR spacer
cacccgcagccgcacccggcggtgcgggag	Protospacer
  *   *****.****** ***********

419. spacer 24.3|4432142|30|NC_020990|CRISPRCasFinder matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 7, identity: 0.767

gccgaccagccacacccgccggtgcgggag	CRISPR spacer
aatgcccagccgcacccgctggtgcgggcg	Protospacer
. .* ******.*******.******** *

420. spacer 24.3|4432142|30|NC_020990|CRISPRCasFinder matches to NC_004808 (Streptomyces rochei plasmid pSLA2-L DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gccgaccagccacacccgccggtgcgggag	CRISPR spacer
ggcgaccagccgcacccgccgctgctgctc	Protospacer
* *********.********* *** *   

421. spacer 30.3|5367183|32|NC_020990|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 7, identity: 0.781

gaggggtacgccatcaccgggcggccgccggc	CRISPR spacer
gtgggcagcgccaccaccgggcgggcgccgga	Protospacer
* ***  .*****.********** ****** 

422. spacer 30.4|5367244|32|NC_020990|CRT matches to KX781992 (Mycobacterium phage Gabriel, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcggcg	Protospacer
.*************** ******.***  *. 

423. spacer 30.4|5367244|32|NC_020990|CRT matches to MK359346 (Mycobacterium phage NoodleTree, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcggcg	Protospacer
.*************** ******.***  *. 

424. spacer 30.4|5367244|32|NC_020990|CRT matches to JN699013 (Mycobacterium phage Pio, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcggcg	Protospacer
.*************** ******.***  *. 

425. spacer 30.4|5367244|32|NC_020990|CRT matches to AY129337 (Mycobacteriophage Bxz1, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcggcg	Protospacer
.*************** ******.***  *. 

426. spacer 30.4|5367244|32|NC_020990|CRT matches to MK112545 (Mycobacterium phage Khaleesi, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcgctt	Protospacer
.*************** ******.***   *.

427. spacer 30.4|5367244|32|NC_020990|CRT matches to MH825697 (Mycobacterium phage Bangla1971, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcggcg	Protospacer
.*************** ******.***  *. 

428. spacer 30.4|5367244|32|NC_020990|CRT matches to MK359342 (Mycobacterium phage ShiaLabeouf, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcggcg	Protospacer
.*************** ******.***  *. 

429. spacer 30.4|5367244|32|NC_020990|CRT matches to NC_004687 (Mycobacterium phage Bxz1, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcggcg	Protospacer
.*************** ******.***  *. 

430. spacer 30.4|5367244|32|NC_020990|CRT matches to MK359321 (Mycobacterium phage Phusco, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcggcg	Protospacer
.*************** ******.***  *. 

431. spacer 30.4|5367244|32|NC_020990|CRT matches to NC_029044 (Mycobacterium phage Breeniome, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcggcg	Protospacer
.*************** ******.***  *. 

432. spacer 30.4|5367244|32|NC_020990|CRT matches to JN204348 (Mycobacterium phage Sebata, complete genome) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tgggccaggtgggcgaaggcctgttcgcggcg	Protospacer
.*************** ******.***  *. 

433. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP036181 (Escherichia coli strain WCHEC025970 plasmid p2_025970, complete sequence) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tcggccaggttggcgatggccagctccgcgcc	Protospacer
. ******** ********** **** .**.*

434. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_MG825377 (Escherichia coli strain 1108 plasmid p1108-emrB, complete sequence) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tcggccaggttggcgatggccagctccgcgcc	Protospacer
. ******** ********** **** .**.*

435. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccgcacaggtcggcgaaggcctgctcgaagcc	Protospacer
* *  ***** ***** *********** *.*

436. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccgcacaggtcggcgaaggcctgctcgaagcc	Protospacer
* *  ***** ***** *********** *.*

437. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccgcgcaggtgggcggtggcctcctcgatgcc	Protospacer
* *  **********.****** *****.*.*

438. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.781

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ccgcacaggtcggcgaaggcctgctcgaagcc	Protospacer
* *  ***** ***** *********** *.*

439. spacer 13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NC_015314 (Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence) position: , mismatch: 8, identity: 0.75

ttcgggctcgccacctcgaccgcgagcacagt	CRISPR spacer
ctcgggctcgccaccccgaccgcgctgctggt	Protospacer
.**************.********    ..**

440. spacer 13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 8, identity: 0.75

ttcgggctcgccacctcgaccgcgagcacagt	CRISPR spacer
ttcgggctcgacacctcgaccgtgaaccgcca	Protospacer
********** ***********.**.*     

441. spacer 13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 8, identity: 0.75

ttcgggctcgccacctcgaccgcgagcacagt	CRISPR spacer
ttcgggctcgacacctcgaccgtgaaccgcca	Protospacer
********** ***********.**.*     

442. spacer 13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NC_023283 (Streptomyces sp. FR1 plasmid pFRL3, complete sequence) position: , mismatch: 8, identity: 0.75

ttcgggctcgccacctcgaccgcgagcacagt	CRISPR spacer
ctcggcctcgccaccccgaccgcgttgatggt	Protospacer
.**** *********.********   *..**

443. spacer 13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 8, identity: 0.75

ttcgggctcgccacctcgaccgcgagcacagt	CRISPR spacer
ctcggcctcgccaccccgaccgcgttgatggt	Protospacer
.**** *********.********   *..**

444. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022424 (Vitreoscilla filiformis strain ATCC 15551 plasmid pVF1, complete sequence) position: , mismatch: 8, identity: 0.75

tcgtcgagggtggcgttcaggaccgtgacgat	CRISPR spacer
acgtcgaggggggcgttcaagacctggtaaat	Protospacer
 ********* ********.****  *  .**

445. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026518 (Deinococcus sp. NW-56 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

tcgtcgagggtggcgttcaggaccgtgacgat	CRISPR spacer
tcgacgaggttggcgttcaggacgaagttggt	Protospacer
*** ***** ************* . * .*.*

446. spacer 17.5|3218234|30|NC_020990|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
gacgggcggtcgtcacggcggaaaccgccg	Protospacer
     *********.**.*********** 

447. spacer 17.5|3218234|30|NC_020990|CRT matches to NC_011143 (Phenylobacterium zucineum HLK1 plasmid, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
acaccgcggtcgtcgcgaccgatggtgtcg	Protospacer
 ****************** ** . .*.* 

448. spacer 17.5|3218234|30|NC_020990|CRT matches to NZ_CP040459 (Pseudomonas stutzeri strain PheN2 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
gttcgttggtcgtcgcgacggcaagcgccc	Protospacer
 . *  .************** ** *****

449. spacer 17.5|3218234|30|NC_020990|CRT matches to NZ_LR134459 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
gcaccgcggtcgtcgcgtcggacgtgggcg	Protospacer
 **************** **** .. * * 

450. spacer 17.5|3218234|30|NC_020990|CRT matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
ccgccgcggtcgtcgcggcggaagcgaaga	Protospacer
**.**************.*****.* .   

451. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP013299 (Arthrobacter sp. YC-RL1 plasmid unnamed 2, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
cgcgcgccacagctcatcgaggatcacaaa	Protospacer
 .*************.*******. * . *

452. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP016082 (Streptomyces sp. SAT1 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
cccggaccacggctcgtcgaggacgagcag	Protospacer
  ** .****.****************  .

453. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP017301 (Rhodococcus sp. YL-1 plasmid pYLC2, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
gtagtcgtgcagctcgtcgacgacgaggta	Protospacer
*  *.  ..*********** *********

454. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP050127 (Rhodococcus erythropolis strain KB1 plasmid plas4, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
gtagtcgtgcagctcgtcgacgacgaggta	Protospacer
*  *.  ..*********** *********

455. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP020556 (Streptomyces sp. Sge12 plasmid pSGE, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
ctggcgccagagctcgtcgcggacgacgat	Protospacer
   ****** ********* ****** *  

456. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP011869 (Pseudonocardia sp. HH130629-09 plasmid pLS1-1, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
ctggcgccacacctcgtcgcggacgacgat	Protospacer
   ******** ******* ****** *  

457. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NC_005284 (Burkholderia phage phi1026b, complete genome) position: , mismatch: 8, identity: 0.733

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
gcactacagcagcgcgtcgaggacgaggta	Protospacer
*   ..* .**** ****************

458. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to AY453853 (Bacteriophage phi1026b, complete genome) position: , mismatch: 8, identity: 0.733

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
gcactacagcagcgcgtcgaggacgaggta	Protospacer
*   ..* .**** ****************

459. spacer 24.3|4432142|30|NC_020990|CRISPRCasFinder matches to NZ_CP015446 (Streptomyces sp. S8 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gccgaccagccacacccgccggtgcgggag	CRISPR spacer
agcgaccagccgcacccgccgctgctgctc	Protospacer
. *********.********* *** *   

460. spacer 30.3|5367183|32|NC_020990|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 8, identity: 0.75

gaggggtacgccatcaccgggcggccgccggc	CRISPR spacer
cccgagaccgccatcagcgagcggccgccggc	Protospacer
   *.*  ******** **.************

461. spacer 30.3|5367183|32|NC_020990|CRT matches to NC_013531 (Xylanimonas cellulosilytica DSM 15894 plasmid pXCEL01, complete sequence) position: , mismatch: 8, identity: 0.75

gaggggtacgccatcaccgggcggccgccggc	CRISPR spacer
tgggctggcgccgtcacccggcggccgccggc	Protospacer
 .**   .****.***** *************

462. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP050093 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b5, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

463. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP050099 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b5, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

464. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP050105 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b6, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

465. spacer 30.4|5367244|32|NC_020990|CRT matches to NC_008384 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

466. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP025014 (Rhizobium leguminosarum strain Norway plasmid pRLN2, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

467. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP053441 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eE, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

468. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP025508 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvB, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

469. spacer 30.4|5367244|32|NC_020990|CRT matches to NC_012858 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132502, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

470. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP050110 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b4, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

471. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP022667 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR2, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

472. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP022566 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK02, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

473. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP050087 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b5, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacc	Protospacer
   ** ****** *************** ..*

474. spacer 30.4|5367244|32|NC_020990|CRT matches to MT740732 (Ralstonia phage Darius, complete genome) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gtgcccaggtcggcgatggcctgctcgcggct	Protospacer
  * ****** ****************  *..

475. spacer 30.4|5367244|32|NC_020990|CRT matches to MT740740 (Ralstonia phage Gervaise, complete genome) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gtgcccaggtcggcgatggcctgctcgcggct	Protospacer
  * ****** ****************  *..

476. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gcggccagcagggcgatggcctgctccaacgc	Protospacer
  ******  **************** *   *

477. spacer 30.4|5367244|32|NC_020990|CRT matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gcggccagcagggcgatggcctgctccagcgc	Protospacer
  ******  **************** *   *

478. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

-cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
acaaacc-ggtcggcgatggcctggtcgacgat	Protospacer
 *...** *** ************ ****** .

479. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP007144 (Hymenobacter swuensis DY53 plasmid pHsw1, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tggtgatggtgggcgatggcctgaacgacgcc	Protospacer
.**    ****************  *****.*

480. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

-cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
acaaacc-ggtcggcgatggcctggtcgacgat	Protospacer
 *...** *** ************ ****** .

481. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP024423 (Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence) position: , mismatch: 8, identity: 0.75

----cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tcctcgttc----tgggcgatggccttctcgacctc	Protospacer
    **  *    ************* ****** **

482. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

-cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
acaaacc-ggtcggcgatggcctggtcgacgat	Protospacer
 *...** *** ************ ****** .

483. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP035511 (Haematobacter massiliensis strain OT1 plasmid pOT1-1, complete sequence) position: , mismatch: 8, identity: 0.75

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ggacgccggtgggcgctggcctgatcgacgcc	Protospacer
 *.  * ******** ******* ******.*

484. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 8, identity: 0.75

-cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
acaaacc-ggtcggcgatggcctggtcgacgat	Protospacer
 *...** *** ************ ****** .

485. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

-cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
acaaacc-ggtcggcgatggcctggtcgacgat	Protospacer
 *...** *** ************ ****** .

486. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

-cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
acaaacc-ggtcggcgatggcctggtcgacgat	Protospacer
 *...** *** ************ ****** .

487. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

-cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
acaaacc-ggtcggcgatggcctggtcgacgat	Protospacer
 *...** *** ************ ****** .

488. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

-cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
acaaacc-ggtcggcgatggcctggtcgacgat	Protospacer
 *...** *** ************ ****** .

489. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP031079 (Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence) position: , mismatch: 8, identity: 0.75

----cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tcctcgttc----tgggcgatggccttctcgacctc	Protospacer
    **  *    ************* ****** **

490. spacer 30.5|5367305|32|NC_020990|CRT matches to NC_004934 (Streptomyces violaceoruber strain SANK95570 plasmid pSV2, complete sequence) position: , mismatch: 8, identity: 0.75

cgttcgaggagatccgctgtggccatcgtgtg	CRISPR spacer
ccctcgaggaaatcggctgtggccatctgggt	Protospacer
* .*******.*** ************  *  

491. spacer 13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 9, identity: 0.719

gccgaggggttgtggatgaggccgccgcgctg	CRISPR spacer
agtgcggggttgtggatcaggtcgccgcgtgc	Protospacer
. .* ************ ***.*******.  

492. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 9, identity: 0.719

tcgtcgagggtggcgttcaggaccgtgacgat	CRISPR spacer
acataatccgtggcgttcaggacctggacgat	Protospacer
 *.* .   ***************  ******

493. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 9, identity: 0.719

tcgtcgagggtggcgttcaggaccgtgacgat	CRISPR spacer
acataatccgtggcgttcaggacctggacgat	Protospacer
 *.* .   ***************  ******

494. spacer 16.1|3158476|37|NC_020990|CRISPRCasFinder matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 9, identity: 0.757

ttccggctcggcggcgggggttgaagacggtgaagtc	CRISPR spacer
cgtggggttcgcgggggtggttgaagacggtgaagtc	Protospacer
. . ** *. **** ** *******************

495. spacer 17.5|3218234|30|NC_020990|CRT matches to NZ_AP018829 (Asticcacaulis excentricus strain M6 plasmid pASEM-1, complete sequence) position: , mismatch: 9, identity: 0.7

ccaccgcggtcgtcgcgacggaaaccgccc	CRISPR spacer
aatttgcggtcggcgcgaccgaaaccgcag	Protospacer
   ..******* ****** ********  

496. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NC_023283 (Streptomyces sp. FR1 plasmid pFRL3, complete sequence) position: , mismatch: 9, identity: 0.7

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
tacgcgccactgatcgtcgaggaccccaag	Protospacer
 ********* * ***********   . .

497. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 9, identity: 0.7

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
tacgcgccactgatcgtcgaggaccccaag	Protospacer
 ********* * ***********   . .

498. spacer 24.2|4432081|30|NC_020990|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 9, identity: 0.7

gacgcgccacagctcgtcgaggacgaggta	CRISPR spacer
tggccgccgcagctcgccgaggacgagccg	Protospacer
 .  ****.*******.********** ..

499. spacer 30.3|5367183|32|NC_020990|CRT matches to NZ_CP041223 (Porphyrobacter sp. YT40 plasmid pYT40, complete sequence) position: , mismatch: 9, identity: 0.719

gaggggtacgccatcaccgggcggccgccggc	CRISPR spacer
tggatccacaccatcaccggccggccgccgcc	Protospacer
 .*.  .**.********** ********* *

500. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP018230 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagacg	Protospacer
   ** ****** *************** .. 

501. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP030764 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.719

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gccgcgaggtggtcgatggcctgctcgagaca	Protospacer
   ** ****** *************** .. 

502. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP022417 (Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-2, complete sequence) position: , mismatch: 9, identity: 0.719

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tcaacatgctgggcgatggcctgcgcgatgtc	Protospacer
. ..*  * *************** ***.***

503. spacer 30.4|5367244|32|NC_020990|CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 9, identity: 0.719

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tcaacctcctgggcgacggcctgcgcgacgtc	Protospacer
. ..**   *******.******* *******

504. spacer 13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.688

gccgaggggttgtggatgaggccgccgcgctg	CRISPR spacer
cccgagaggttgtggctgaggccgtggttggt	Protospacer
 *****.******** ********. *.    

505. spacer 13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NC_008043 (Ruegeria sp. TM1040 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.688

gccgaggggttgtggatgaggccgccgcgctg	CRISPR spacer
aaatggatgtggtggatgaagccgccgcgctc	Protospacer
.   .*. ** ********.*********** 

506. spacer 13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 10, identity: 0.688

gccgaggggttgtggatgaggccgccgcgctg	CRISPR spacer
cccgagaggttgtggctgaggccgtggttggt	Protospacer
 *****.******** ********. *.    

507. spacer 13.2|2718872|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 10, identity: 0.688

gccgaggggttgtggatgaggccgccgcgctg	CRISPR spacer
cccgagaggttgtggctgaggccgtggttggt	Protospacer
 *****.******** ********. *.    

508. spacer 13.3|2718933|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046574 (Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgggctcgccacctcgaccgcgagcacagt	CRISPR spacer
aacgtgctcgccacctcgaccgggattccgtc	Protospacer
  ** ***************** ** . *. .

509. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029234 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436d, complete sequence) position: , mismatch: 10, identity: 0.688

tcgtcgagggtggcgttcaggaccgtgacgat	CRISPR spacer
aatgaaatggtggcgctcaggaccgtgaagag	Protospacer
     .* *******.************ ** 

510. spacer 13.4|2718994|32|NC_020990|PILER-CR,CRISPRCasFinder,CRT matches to JQ015307 (Pectobacterium phage phiTE, complete genome) position: , mismatch: 10, identity: 0.688

tcgtcgagggtggcgttcaggaccgtgacgat	CRISPR spacer
atgtcacgggtggcgttcaggaccgcatggcc	Protospacer
 .***. ******************..  * .

511. spacer 30.3|5367183|32|NC_020990|CRT matches to NZ_CP022542 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence) position: , mismatch: 10, identity: 0.688

gaggggtacgccatcaccgggcggccgccggc	CRISPR spacer
ggcatccgggccagcaccgcgcggccgccggc	Protospacer
*. .  .. **** ***** ************

512. spacer 30.3|5367183|32|NC_020990|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 10, identity: 0.688

gaggggtacgccatcaccgggcggccgccggc	CRISPR spacer
cgcaggtcccccatcaccgggcggccgttgcg	Protospacer
 . .*** * *****************..*  

513. spacer 30.3|5367183|32|NC_020990|CRT matches to MK113951 (Phage 5P_3, complete genome) position: , mismatch: 10, identity: 0.688

gaggggtacgccatcaccgggcggccgccggc	CRISPR spacer
aggaaacgcgccatcaccgggtcgccgccggt	Protospacer
..*.....*************. ********.

514. spacer 30.4|5367244|32|NC_020990|CRT matches to NC_015951 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI01, complete sequence) position: , mismatch: 10, identity: 0.688

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ttcttcaggtgggcgatgccgtgctcgacccg	Protospacer
.   .************* * ******** . 

515. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP027023 (Streptomyces sp. WAC00288 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.688

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ttcttcaggtgggcgatgccgtgctcgacccg	Protospacer
.   .************* * ******** . 

516. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP027024 (Streptomyces sp. WAC00288 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.688

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ttcttcaggtgggcgatgccgtgctcgacccg	Protospacer
.   .************* * ******** . 

517. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP027026 (Streptomyces sp. WAC00288 plasmid p4, complete sequence) position: , mismatch: 10, identity: 0.688

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ttcttcaggtgggcgatgccgtgctcgacccg	Protospacer
.   .************* * ******** . 

518. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP043960 (Streptomyces tendae strain 139 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ttcttcaggtgggcgatgccgtgctcgacccg	Protospacer
.   .************* * ******** . 

519. spacer 30.4|5367244|32|NC_020990|CRT matches to NC_008043 (Ruegeria sp. TM1040 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.688

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
tcaatctcatgggcgatggtctgcgcgacgtc	Protospacer
. ...*  .**********.**** *******

520. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP024150 (Escherichia coli strain 14EC033 plasmid p14EC033c, complete sequence) position: , mismatch: 11, identity: 0.656

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
gtcgccatgtgggcgatgccctgctcattaca	Protospacer
   **** ********** *******. ... 

521. spacer 30.4|5367244|32|NC_020990|CRT matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 11, identity: 0.656

cgggccaggtgggcgatggcctgctcgacgtc	CRISPR spacer
ttcagcaggtgggcgatgccctggtcgagcgg	Protospacer
.  . ************* **** ****    

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	3003079 : 3063916	57	Streptomyces_phage(28.57%)	protease,transposase,integrase	attL 3021344:3021386|attR 3064043:3064085
DBSCAN-SWA_2	3322761 : 3380877	51	Tupanvirus(14.29%)	tRNA,transposase,integrase,holin	attL 3338061:3338084|attR 3384468:3384491

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_020990|3003079:3063916|DBSCAN-SWA
CATGCTGCACTCCCGATGGTTCAAGACGGCCGGCGCCGCCGCGGCCCTCACCCTGGCCACCGCCACGGCCGCCTACGCGACCCCCGCCCCCGCCCCGGCCCCGGACCTCACGGCCGCCGCGGTGACCCTCCGCTACGACGACAGCCGCGCCGCCGGCTGGGAGGCGGCCATCGCCGCCGGGGTCGCCAACTGGAACGCCTCCGTCAGCAACGTCCAGCTCGTCGAGGCCGCCCCCGGCACCCGCGCCGAGATCCAGATCATCGCCACCAGCGGCTGGCCCCAGGCCACCCTCGGCCCCGTCCGCCCCGGCGGCACGGCCAGGGTGGAACTCGGCAGCCAGGCCGTGACCGAGGGCCACGACAAGACCCGCATAGCCGCCCACGAACTCGGCCACAGCCTCGGCCTCCCCGACACCAAACCGGGCCCCTGCAGCCAGCTGATGTCCGGCTCCACCGGCGGCACCACCTGCAAGAACGCCACCCCGAACGCCACGGAGCGCGCCCGCGTCCAGTCCCTGTACGCAGGCGGCTTCACGTTCCTCGTCCCGGCCGACGGACGGGTGCTGGTGGACGCGCCGTAACGGGGCGCCCCCACCGGACGCCCCCCGCGCGCCCCGGTCCCCACCGCCCGGCCGGAGGCCGGGGCGCGCGAGGAGCACGGCCCCGCCGAGGCGGCGGGAGGCGGCCCGGGGGACGCCCTGTCCGGCCCCGCCCGCCCCGATGGGACAATCCCGGAATGGCAAATCCGCAAGTATTCTTCGACATAGAAGCGAACGGCACCTCCCTCGGCCGTGTCACCTTCGAGCTCTTCGCCGACGTGGTCCCCAAGACCGCCGAGAACTTCCGCGCCCTGTGCACCGGCGAGAAGGGCAACGGCAGGCAGGGCAAGCCCCTCCACTTCAAGGGGAGCGGCTTCCACCGCGTCATCCCCGGCTTCATGTGCCAGGGCGGTGACTTCACCCGGGGCAACGGCACCGGCGGTGAGAGCATCTACGGCGAGAAGTTCGCCGACGAGAACTTCCAGCTCAAGCACGACACCCCCGGCATCCTGTCGATGGCCAACGCCGGCCCGCACAGCAACGGCTCGCAGTTCTTCATCTGCACCGAGCCCACGCCGTGGCTGGACGGCAAGCACGTCGTCTTCGGCAAGGTCCTCGACGGCATGGACACGGTCAAGGCCATCGAGTCCCACGGCTCCCGCAGCGGCAAGACCTCCGCAACCCTGACGATCAGCGACTGCGGCCAGATCTGACATCGCACGGCAACCACCCCGGCCGCCGCGGGCACGAGCGCGCGGCGGTCGGGGGGCGGCCGTTCAGCCGCCGGGGCTCATCCCTTGCCGACGTCCAGCACCGCACGCGCCTCGGGTACGTCCGCGAGCTGCTTGAGTCTCTCGGTCACCACACGGACGCGTTCAGTGGTCCGTTTACTGGCCACGTCTGAGGACAGCGAGGTCACATGCCCGGCGATCACGGCCGCTTCCTCAGGCTCGTTGGCGTCGGCGTAGCTGGATCTCATCAACCTGTCGTACGCCGAAGCGAAGTCCCGCGCGTCCCTGCAAGAGGGCCAGTCGGTGCCCCTCGGGTGGCCTCCCGATGCCGGCCCCGACACGTCCGTCAGCCGCGAGCCCTGGCAAGCGCGACCAGACCGGCGAAGCTCTCCCGGGACAGGGTGAGGTGAGGGCCGTTCTGCACCTTGCTGTCCCGCACCAGGAACTCACCCGTGGCCAGGGCGTGGGCGGGGGCCCACTCGACACACTGGCCGCCTTCGCCACTGCTGTAGGAGGAAGCGGTCCAACGAGGGGTTTCGGTCATCACTGGGTCTCCTTCTGTGGTGGTCCGATCACGGCCACGGATGCCGCCGAGTAAGCATTCCCCACACGCTGGAATACCGACACACACCCGACAGCAACCGAAAGCACCGCCGCACTCCGAGACGGAGGCGACGGCGCCTTCAGCACTGAACGTCAGCCGTGCGACTTGGCGAGCGCCACCAGACCGGCGAAGCCCTCCTGGGACAGGGCGAGGTGAGGGCCGTTCTGCACCTTGCTGTCCCGCACCAGGAACTCACCCGTGGCCAGGGCGTGGGCGGGGGCCCACTCGACACACTGGCCGCCTTCGCCGCCACTGTAAGTGCTCTTGACCCACTGGTCGGGCCGCAGCCCGTATGCCCTACTCATGTGGCGTACTCCTCCGAGATATCTCTGATGAGGGCCAAGGACTCCTCCGGGGCTCGCGCCGAGGCTCGAAGGTGTTCGTAGGCCGTGCGCGCGTCGTCCACTACGGCCGCCGAGTCTGACACGTGCCCCTGCCCTCTGGCCTCCGAGTACAGGACTGTCGCCCCGTCATCCGGTGTAAGCAGGGTAAACGGTAGAGACGAGGCCGGGGCACCCGCAGTGAAGGGCAGAACCTGGACTGTGATGTGAGGGTTTCCCGCGTCTGAGGCAAGGCTGCGAAGCTGCGCCGCCATAACGGCACGGCCACCCACACACGTACGCAGAACCGACTCGTGCAAGATCACCCACAGCATTGGCGGGGCGTCCCTCGTCATCACGTCGCGCCGGGCCAGCCGGGCCTCCACTCTGAGCTTGATCTGCTCCTCGGTCTCACGCGGGTGGGTGGCCCTGAACGTGGCTGCCGCGTACTCCGAGGTCTGCAACATGCCCATGATCAGAGCGTTGGAGTAGTCCTCGATGCGACTGGCCTGTTTCTCCAGGTTGATGTACGGGATGAACCAACCAGGGTGTCCGCCTTCGCTGATCCACGCCAGCAACCGCGAAAAGGAACCGGAGGTATTAAAGAACCGGTCGCACCCCTCCGCGAAGGCCGGAGACGGCATCGCCTTACCGTTCTTGGCCTTACTGACATAGGGCTCCTTGTAGCCGGTGAAGTCGGCCAGTTGCCGTTGACTGGCGCCCCGGTGGAGCAGCGCAGCCGCTAGCTCGCGCCCGAACCATTCGAGGCCGTTCGCGGGCTGATCGCCCTGACTGGGTGACGCATCGATCACGAGTCCCACTTCCACTCTTTCCAAATGCGTTGGAAAGGCTCCAGACCTGTTGAGCGTACCGCCGCCCGCGTCACTCTGTGTTCACTGTCGATAGCTCAACCACAACCCAGTGAACCGTGAGGACACCACTCTCATGACCCCCGAATCCCAGCCGTCCACCCCCACCAATGAACCCCCCACCCCTTGCCGCACCTGCCAGGAATTCACCCTCGCGGAAGCCGTCGCCAACGGTGAGCGGGACTGGAGCAAGGCGACCGACTGTCGCGTACTGCGCAAGCGGCACCAGGAGGCGGGCGAGTGCCTGGGCCGGGAGGCGGGGTGAGCGGTGTGGAGTCGGGCCCGCCGGAACCCGAGTTCAACCCGCTGCGGTACCCGCCCTGCGCCTGCCCCCTGCATCGCGCCGAGCGCGAGCCCGAGCAAGAGACGGATCAGGAGCCCAGGTCCGAGCCCGGCGAGGACTCCCCCTCCCTGCGCGAACTCCGCGCCCTCGTCACCGAGGAGAACCGCCTGCGCCGCTGGCTGCGGGGATCGTCGTGAACGGGGGCGTCGAATATCTCGCCGAAGTCCACGCGGGTTCCGGCGCCGTCCGTTTCTTCCTCGGCGGGACTCTCGCCCCCACCCGACGCCTCGCACTCCGCTGGTTACGCCGCCAGGCACACCGCTTCGCGGACGGGCTCGACCCCGACCCGCGTACCGCGAAGGTCCCGGCCGGCGCCCTGCGGCCCGTACCGGCCTATGCGGGTGACGCCCCGGCCGAGCTTCGCCGGTGGGCCACCGATCTGGCCGAACAAGACCGCGCAGCCCAGCAGTTGGCCGCCGGCCGCACCTACCTCTTCGTCGCCCGCGAAGAGGCGGCCTGGTACCTGCTCGCCGCCCGTCCCCTGCTCACCGCTCCCCCGGCTCCCACTCCAGCAGCCGCACCTTCGCCACCGTCCGCACGTGTCTGCGCATCGCCGCCGCGGCCCGCTTCGCCTCCCCTGCCTCGATGGCGTCCAGGATGGCGTGGTGCTGGGCCAGTGACCGGTCGGGGCGGCCCGGCTGGCGGAGGGATTCGCGGCGGCTCTCGGTGATCTGGTCGGTGAGGGAGGCCATGAACTCGGCGAGGAGGGGGCTGTGGCCGGCCTCGGTGACGGCGGCGTGGAAGAGGCGGTCGCCCTCCTCGCCGTGGCCGCCGGAGGCGATCTCCCCGGCCATGTGGGCGAGGGCGGCGCGCAGGGCGGTGAGGTCGGTCTCGGTGCGGCGGGTGGCGGCGAGTTCGGCGAGTTTGGTCTCCAGGGCCTCGCGGGCCTCCAGCACGTCGGGGAGGCGGCGCCGGCGTTCGACGAGGCGCTCGACCGGTTCGTGGTCGAGGGTGTCGCGGAGCAGGTAGGTGCCGCCGCCGTGCCGGGTCTCCACCAGGCCCTGGACCTCCAGGACGACCACGGCCTGCTTGACGGAGGCGCGGCTGACCCCGAGGCGCTGGGCCAGGTCGCGTTCGGCGGGCAGGCGGTCGCCGGCGGCGAGGCGGTGCTCGGCGGCGTAGGCGCGGAGGCGTTCGAGAACCTGCTCGTAGAGGCGGGTACGGCCCATCGGGCGCAGCGCGTCGTCGGTCATGCGTAACCCCTGTCCTCCTGCTCCCCCGGGCGCCCGGAGCGTAACACCGGGGCCCGGGGCGGGCCTTGCGCCGGCCTTGATCCGTACCCGGTGGCCGAGTGGCTGAACCAATTCGTGCGCGACCCGTTGACACCCGGCGCGCCAGGGCCGAGCGTGGTCCAGCCACTGGGCCAATGAGGCGTTCCGCTTCGTCGGCTCCGGGTCCTTTCGGGCTCAACACCCCACTGGACCCCGTGACATGACCCATTGGGACCCATGGGACGGGAGCCCCTGATGTCTGCCGAACTACTCTCCATCCTGGTGCTGGCGGTGCTGTTCGTCGTCGGCACCACCCGCTCCGTGAACATGGGCGCGCTGGCCTTCGCCGCCGCCTTCGGGGTCGGCACGCTGGCCGCCGGGCTCGACGCGGACGGGATCTTCGCCGGATTCCCCGGTGACCTGTTCGTGGTGCTGGTCGGCGTCACGTACTTCTTCGCCATCGCCCGCGCCAACGGCACCACCGACTGGCTCGTGCACGCCGGAATCCGGCTGGTGCGCGGCCGGATCGCGCTGATCCCCTGGGTGATGTTCACCGTCACCGGGGTGCTGACCGCGATCGGCGCGGTCAGCCCGGCGGCGGTCGCCATCGTCGCGCCGCTCGCCATGGGCTTCGCCGCCCGGTACGGCATCAAGCCGCTGCTGATGGGCGCCCTCGTCGTGCACGGCGCCCAGGCCGGCGGCTTCTCGCCGATCAGCATCTACGGCTCGACCGTCAACGGCATCCTGGAGCGCGAGGGGCTGCCCGGCAGCCCGATCGCCCTCTTCCTCGCCAGCCTCTTCGCCAACCTGGCCATCGCCGCGCTGTTGTTCGTCGCGCTGGGCGGACTGCGGTTGCGGGGGCGGGACTTGGGTGACCTGGGTGACGAGGAGGCCAAGGAGGCCAAGGAGGGCGGTGGCGGCTCCGGCGGTACGGGCGGGACGGTCACCGGCACCCGCGCCCGCACCACCCCCGACGCCGACCTCCTGCGCCTGACCCCGGCCCGGATCGCCACCCTGGTGGGGCTGGTCGCGCTGGTCGTCGCCGTGCTCGTCTTCGACCTGGACGCGGGGCTGACCGCGATCACCCTCGCCGTGCTGCTCGCGGTGGTCTGGCCGGAGGACAGCAAGGCGGCGGTGGCGCACATCACCTGGCCGACCGTGCTGCTGATCTGCGGGATGCTCACCTACGTCGCGGTGCTCCAGGAGATGGGGACGATCGACTGGGCGGGCGAGCACGTCGGGTCGATCGGGATTCCGCTGCTGGCGGCACTGCTCTTCTGCTACATCGGCGCGGTCGTCTCCGCCTTCGCCTCCTCGGTCGGGATCATCGGGGCGCTCATCCCGCTCGCCGTGCCCTTCCTGGAGCAGGGCGAGATCGGCGTGGTCGGGATGGTGGCGGCGCTCTCGGTGTCGGCCACCGTGGTCGACGTCAGCCCCTTCTCGACCAACGGCGCGCTCGTACTGGCCGCCGCCGAGGACACCGACCGCGAGCGCTTCTTCCGGCAGCTGATGCTGTACGGCGGGGCCGTCACGCTGCTGGCCCCGCTCGTGCTCTGGCTGGCGCTGGTGGTGCCCGGCCTCTGACCTGGGTAACCCTGGTCAGGAGGCGCCGCCTGGCCAGGGCGCCTCCGCCCGCCCCCGACCGGCGCAGCACCACACCCGCCCGACCCCGAGGAGAACCACCCGTGACCTCGTCCGCCACACCCGAGACGGCATCCCTCTTCCCGGCGCTGCACACCCCGCCGGTCCCGCCGAAGCCCGCCCTCCGCTTCGGTGACCGCACCCTGGAGTACGGGGAGGTGGCCCGCCTCGCCGGGGCGCTCGCCCGTGAACTGCCGCTCGGCCGCCGGGTCGCCGTCTGGGCGACGCCGAGCTTGGAGACCGGCGTGGCGGTGGTCGCCGCGCTGCTCGCCGGGGTGCCCGCCGTACCGCTCAACCCGAAGGCGGGGGCGCGCGAGCTGGCGCACATCCTCGCGGACAGCGATCCGGCGCTGGTGCTGGCCGCGCCCGGTGAGGTGCTGCCCGAGGAACTGGCGGGGCTGGCCCGCCGGGACGTGGCGACCGACCCCGAGGCCCTGCCGGGCGCCGTGGCGCTGCCCGCCGAGCCGGGGCCCGAGGCGCCCGCGCTGATCGTCTACACCTCGGGCACCACCGGCCCGCCCAAGGGCGTGGTCCTGCCCCGGCGCGCCCTGACCAGCACGCTCGACGCGCTTCAGGACGCCTGGCAGTGGACGGCGGACGACATCCTCGTGCACGGCCTGCCCCTCTTCCACGTGCACGGCCTGATCCTCGGCGTCCTCGGCCCGCTGCGGCGCGGCGGCTCCCTGGTCCACCTGGTCCGCTTCTCCACGGACGGGGTGCGCCGGGCGCTGGAGGAGGGGGCGACGCTGATGTTCGGCGTCCCGACCATGTACCACCGCATCGCCGAGGAGGCCGCCGGGGACCCGGCGCTCGCCGCCGCCCTCGCCAGGGCGCGGCTGCTGGTCTCCGGCTCGGCCGCGCTCCCCGTCCACGACCAGGAGCGCATCGCCGCCGCCACCGGCCGCCGGGTCGTCGAGCGGTACGGGATGAGCGAGACCCTGATGAACACCAGCGTCCGCGCGGACGGCGAGCCCCGCCCCGGCACGGTCGGCGTGCCGCTGGCCGGGGTGGCGCTGCGGCTGGTCGAGGACGACGGCAGCGAGATCGCGGAGTGGGACGGCGAGACGGTCGGCGAGATCCAGGTGCGCGGGCCGAACCTCTTCACCGCGTACCTGAATCGTCCCGACGCCACCGCCGAGGCGTTCGACGGCGACTGGTTCCGCACCGGCGACATGGCGGTCCGCGAGCCCGACGGGTACGTGCGGATCGTCGGCCGGCGCGCCACCGACCTGATCAAGTCCGGCGGTTACAAGATCGGCGCGGGCGAGATCGAGAACGCCCTGCTCGACTTCCCGGGCGTGCGCGAGGCCGCCGTCACCGGCGAGCCCGACCCGGACCTCGGCGAGCGCGTAGTCGCCTGGCTGGTCACCGACGGCGGCCCGGTCGACGCACAGGCGGTCGCCGACCACGTGGCCCGCCAGCTCGCCCCGCACAAGCGCCCCCGCGTCGTCCGCCACCTCGACGCCCTGCCACGCAACGACATGGGCAAGATCATGAAGCGGGCCCTGCATGGCTGACCGCGACGCCCTCACCGCCCGCGCCCTGATCGCCTCCCTCGACCCTGACTACGTCGAACTGGGCTTCTTCGGGCCGGAGTTCACGGACGGCCCGCTGGAGTGGTCCGGCTACGGCGCCGCCCGCGAACGGGCCCGCGCACGCACCGGCGAACGCGAGTCCGTCGTCTGCGCCACCGGACGGGTGAGGCCGGGGTCCGGTGCCGCGCCCGCCCCCGAAGCCGTCCTGATCGCCTTCGAGTTCGGCTTCCTCGGCGGCTCGCTCGGCGAGGCGACCGGCGACCGCATCGAGGCGGCGTACGCGCACGCCCGCGCCCACCGGCTCCCCGTCGTCTCCCTGGTGGCGACGGGCGGCAGCCGGATGCAGGAGGGGATGCGGGCGCTGACCCAGCTCCAGCGCGTGGCCCGGCAGACCGTGCTGACCCGGCGGGCCGGGCTGCCGCAGCTCGCGGTGGTCCGCGACCCCACCACCGGCGGCGGCTGGGCCACCCTGGCGGCCGGTGCCGACGTGGTCCTCGCCCTGCCGGGCGCCCAGGTCGGCTTCGCCGGCTCCCGGGTCCGCCCGGCCGACGCCGACCCCTGGGCGTACACCGCCGAGGGCCAGCACGCGGCCGGGCACATCGACGCCCTCACCGAACCTGTCGACCTGTCGGACGTACTCGGGCGGTGGCTGGCCCTGCTCGCCGGCCAGGCCGCCCCGGCCCGCCGGGCCGAACCGCCGCACGCCCTGACCACCGGCCCCCTCCCGGCCGACGGCGCCGAGGCCGTCCGCCGCACCCGCTCCCTCGAACGCCCCCGCGCCGACGCCTACCTGGACGCCTACTTCGACTGGCGCGAGGAGATCCGGGGCGACCGTACCGGCGCCACCGACCCCGGTATGCGCTGCGGCTTCGGCCACCGCGACGGCCGGACCGTCGCCTACGCCGCCCAGTGCGGCACCGCCACCCGGCCCGCCGGATTCCGCACCGCCGCCCGCCTGGTCCGCACCGCCGACCGGCTCGGCATCCCGGTCCTCACCCTCATCGACACCCCGGGCGCCGCCAACGACGCCGCCGCCGAACAGGGCGGCGCCGGGCCCGCCATCGCCGACCTCTTCGCCGCCGTCGCCGAGGCCGAGGTCCCCGTCACCTCGCTCCTCGTCGGCGAGGGCGGCTCGGGGGGCGCGCTGGCGCTGGCCGCCCCCGGCCACCTCTGGGTCACACCCGACAGCTACTTCTCCGTCATCGCCCCCGAACTGGCCGCCGCCATCCTCAAGCGGCCCCCGGAGGAGATCCCGGCCACCGCCGACGCGCTGCGGCTGCGCCCGCAGGACGCGGTGGAGCTGGGGGTGGCGCGGGGGGTCGTGCCGGGCCCGGCCTAGGAACACGCGCACGTGCGGGGCGCCCCGGCCGGACGCCCCGCACGTGCCTCCCCCGCTCCCCCGTGTCCCCCGTATCCCCGCAGGTCAGATGGCGGGCACGGCCGCCCCCGTGTTCCGCATCAGCCGCATCAGCACGCGCAGGGTGGTCGCGTACTCGGCTTCGGAAATGCCCTGGTGCATCTCGGCGCCCCATTCGGGGGCCCGTGCCTTGAGGTCGGCGCGGGCCGCGTCGCCCGCCTCGGTGATCCACAGCCGGCCGTCGCCGTCCCGGGTCACCCAGCCGGAGGCGAGCAGGACCTCCGCCTCGGCGGCCAGATCGTCCTCGGGCCGCAGGAACGACACCATCGCGGAACGGAGTTCCTCGACGGTCCTGCCCTGCCCGTCCTCGGAGACGTCGTTCGCCGACAGGAACCGCAGCATCCAGAACCGGGGCTGCGTGAACCCCACCTCGGCCTGCTTCCGCCGCACGAACCCGATGGTCGCCTCGTACGCCAGCTTGGTCCAGTACGGGGCGGGCTGGGACGCCAACTGCGCGTCGGTGTACTGCACATCAGCGGTCACGGTGCTGTCCCCTCGTCACGGCGGCCCCAGGTCGGGCCGACGCGACCCAACGTAGAACCTCGACCAAGGTTGAGGACAAGGGCGGCCGGAGAACGCCGTACGGACGGCGGGCTTGCGTCTCCAGCGGGTGGAGACCCGAAGGTGGGGGCATGGACGACCATCCCCTCCACCCCATCGGCGAGCTGTCCCGCCGGACCGGCACCCCGGTCCGGACCATCAGGTTCTACTCCGACGAGGGCCTCCTGCCCCCGGCCGGACGCTCCCCGTCCGGCCACCGGCTCTACGACGAGGCGGCGGCCGGGCGGCTCGCGCTGGTGCGGACCCTGCGCGAGCTGGGGATCGGCCTGCCGGCCGTCCGGAAGATCCTCGACCGGGAGCTGACGCTGCCGGAGGTCGCCGCCGCGCACACCAAGGCCCTGGACGCGCAGATCGCCGCCCTGCGGGTACGCCGTGCCGTCCTGGACACGGCGGCACGGCAGGGCACCGGTGCGGAGGAGATCCGCGCCCTGCACCAACTCGCCCACCTCTCACGGGGCGAGCGGAAGTCCCTCGTGGACGCGTTCCTCACCGCCGTCTTCGGGCCGGAACCGGGCCTGCCGCTCGCGGGGGTCGCCCGCACGCTGACCCCCGAGCTGCCCGACGAACCCGACGCCGCCCAGCTGCGGGCCTGGCTGGAACTGGCCGCGCTCACCCGGGACCCCGGCTTCCGCGCCCACCTCCGCGGCCTCTGCCAGGAGGCGGCCCCGGGGACGGGCACTCCGGGCGTCCCCCGCCCCGACCTGACCGCGACCGTCCGCGAGATCGTCGCCCCGGCCCTGGCGACGGGGCTCGCCCCCGACTCGCCCCGGGCCGAGGAGATCCTGACCGTCCTCCTCGCCCGCTGCGCGCCCCCGCCCGGCGGCGCCGAGGCGGAGCGGGTGCGGAAGCTGACGGCGAGGCTGGAGCGGTACACCGACCCGCGCCGCGAGCGGTACGTCCGGCTCCTCGCCGTGGTCAACGGCTGGCCCCCGCCCAGCAGTACGCGCCCGGCGCTGACCTGGGCCACCGAGGCCCTGCGCGCCCGGCGCGGAACGGAGCCGGTCAGTCCGCGAGCAGCGACCGGTGCATGATGTGCAGCCCGACATACCCCTCGCCCGGGTGCCGGAACCCCTCGGGCAGCGTGCCCAGCACCTCGAAGCCCAGCGACTCGTACAGCTTCACCGCGCGGGTGTTGGTCTCCACCACGGCGTTGAACTGCATCGCCCGGTACCCCTCGGCCCGCGCCCAGTCGATGGTGTGCGTGCAGAGCGCGCGGCCCACGCCCCGGCCGCCGTGCGCGGGGTCGACCATGTAGCTGGCGCTGGCGATGTGGCTGCCGTTGCCCATGTGGTTGCGGTTCATCTTGGCGGTGCCGAGGACGGTCCCGGAGTCGTCCACGGCGACCACGGTGCGGCTCGGCGCCTTCACCATCCACCAGCCCTCGGCGTCCTCGCGGGAGAGGTCGAGCGGGTAGGTGAAGGTCTCGCCCGCGCGAACGATGGACTCGAAGAACGGCCAGATGGCGTCCCAGTCCTCGGTGCGGGCCTCACGGATCAGCATCCGGCCATCCTCGCCGACGAACGACCAGGTGGTCCACGGTATTTCCCGGGCGGACACGGGCGTGCCCTTGACCTCGACTCCGCTTGAGTTTCTAGCTTCGGCCGGGCACGACGACCGACGCCGAACCGTTCCTAGGAGCCCGCATGCCTGCCACCGAGGCCGTCCCCGCCGCCTACCGCCACGCCGTCGTCCCGCACCTCCTGGTCGACGACGCCGACGCCGCCCTCACCTTCTACCAGCGGGCCTTCGGCGCCGAGCCGCGCTTCCGCCTCGACGGCGACCAGGGCGAGGTGGTGCACGCCGAACTCACCGTCGCCGGGGCCGTCATGATGCTCGGCGACGCCCGCGACACCCTGCGCTCCCCGGCCGCGCTCGGCGGCACCCCGGTCATCCTGCACGTCTACGTCCCCGACGTGGACGCCCTCACCGCACGGGCCACCGCCGCCGGGGCCGAGCTGCTGGAGGGCCCCGCCGACCAGTTCCACGGGGACCGCACGGCCATGCTCCGCGACCCCTTCGGCCACCTGTGGATCTTCCTCACGCACCTGGAAGATCTCACCCCGGAGCAGATCGCGGAGCGCCTGGCCGAGGCGGACGGCACCGCCGGAGCCACCGGCTGACCTCGGGGAACCCGGTGACAGCACGGCGCGCGCTCCGTACGCTGGCCCACGGTCCGGCCCCGTCCGGGCCGCCGTGCCGTGCCGTCCCGCCCGCCCCGGAGGAACCCGTGTCCGCCACTCCCGGCCCCCTGAGCGACGTCTCCCCGACCACCCTCGCCGACCTCCTCGGCCGCGAACAGGTCATGGACTTCGGGCTGCGGACGCTCTGCCCGACCCCGCCCCGGGTCGCGGGCCCCGCCTTCACCGTGCGCTGCGCCCCCGGCGACCAGCTGATGCTGCACGCCGCGATCTACCGGGCGGCACCCGGTTCGGTCCTGGTGGTCGAGGGCGGCGGCACCGAGTACGCGGTGGCCGGGGGCAACGTCTGCGCCGTCGCCCAGCGCCGGGGCATCGCCGCCTTCGTCGTGGACGGCGTCGTGCGCGACCTGGCCGAGATCCGCGCCTCCGGCTTCCCCGTCTTCGCCCGGGGCGTCGTCCCCAAACCCGGCACCAAGAAGGCGGCGTTCCCCCTGAACGGGGAGGTCCGCTGCGGCGGCGTCACGGTACGCGCCGGTGACCTGGTCGTCGCCGACGAGGAGGGCGTCGTCGTGCTCCCCGCCGCCCGGCAGGACGAACTCCTCCAGGCGGCCCGCGCCAAGGAGGCGAAGGAGGCGGCCCAGTCGCTCGACGCCTGGGAGACCGACCACTACGCCCGCATCCAGCAGGCCCTCGACGCCCAGGACTTCACCGGCTGAGGCCGGTCCCGCACACCCGAACGGAGCCCCGCATGCCGCTGCGCTGCGCCCTGCTGAACGACCACCAGGGGGTCGCCACCACGGCCGCCGACTGGTCCCCCGTCCTGGACCGCGTCGAGCTGACCTCCTTCCCGGACCATTTCGGCACCGAGGACGAACTCGCCGCCGCGCTCGCCGACTTCGACATCGTCGTCACCCTGCGCGAACGCGTCCCCTTCCCCGCCTCCCTCTTCGCCCGCCTCCCCCGCCTGCGCCTGCTGGTCGCCTCCGGCATGCGCAACTCCGCGATCGACCTCGCGGCGGCCCGCGCCCACGGCGTCACCGTCTGCGGCACCGACAGCCACTCCACGCCCCCCGTCGAGCTGACCTGGGCCCTCATCCTCGGCCTCGCCCGCAACCTGGTCGCCGAGAACACCGCCCTGCGCACCGGCGGCCCCTGGCAGTCCACCGTCGGCGCCGACCTGCACGGACGCCACCTCGGCGTGGTCGGCCTCGGCCGGATCGGCTCCCAGGTCGCCCGGATCGGCGCCGCCTTCGGCATGGAGGTCGCCGCCTGGAGCCCGAACCTCACCGAGGAGCGCGCCGCCGAGCACGGCGTCCGCCTCGCCCCCGGCCTGCCCGAACTGCTGGCCGACAGCGACGTGGTCACCCTCCACCTCAAGCTGGGCGAGCGCAGCCGGGGCATCATCGGCGCCCGCGAACTGGCCCTGCTGAAGCCCACCGCGTACCTCGTCAACACCTCCCGCGCCGCCCTGGTCGACCACGACGCCCTCCTCGCCGCCCTGAACGAGGGCCGCATCGCCGGCGCCGGCCTCGACGTCTTCCCCACCGAACCCCTCCCCGCCGACGACCCGGTCCGCACCACCCCCCGCCTCCTGGCCACCCCGCACCTCGGCTACGTCACCGAGCGCACCTACGCCACGTACTACCGCGAGGCCGTCGAGGACATCGCCGCCCACCTGGACGGCACCCCGGTACGCGTCCTCGGCTGAGCCCCGCCCGGCCCCTCACCCGGTCAGGTCCCGCAGGTGCGGCACCGCCCGGGTCAGCTCCCGTACGCCCCAGGCGATCAGCGCCACCCCCGCCAGCTCCGGCACCACCCACCAGCCGCCGCGCACGCTCTCCTCGAAGACCACGACACCGAGCAGGAGACTGACCGAGGCGTCCCCGATGGTCAGCGCCGGCTGCGAGGCGGCGAGCGGCCCGGCCTGCAGGGCGTTCTCCAGCAGCAGCACGGCTGCGACCCCGGTCACCGCGAACCCGTACGTCTGCCAGGTCGTGAGGAACGCGATGAACCCGTCGTCGGCGAGCGTGCCCGTGGCCGACTTGAGCAGCGCCGCCGTCAGGGCGTTCCCCACGGCGGCCGCGCAACCGAGCGCCGCCGCCCGGAACAGGGGCGACCGGTTCACCCGCGAGGCCACCACGGCCAGCGCCATCGCCCCCAGACACCCCACCAGCACCGGAATCCACCGCGTCATCGGCGCATCGGTACGCGCCCCCGCCGGCGCCGCCGCCCCCAGCACCGCGACCAGCCCCACCACCACCGCCGCCACCGCCCACCACCCCTCACGCGGCAGCCGCCGGTGCAGCAGCGGCACCCCGATCAGCAGCGCGAACGGCAGCTCCAGCACGAACACCGGCTGTACCAGCGCCAACGGCCCGTTGACCAGCGCCAGCGCCTGGAACAGGGCGGCCCCCACGACCCCCGCGATCCCCAGCAGCCACACCGGCTTCCGCGCCAGCTCCCGCAGCAGCCGCCACCCCCCGCCCGACGCCACCTCGGAGGCGGCCTTCCGCTGGAAGGCGGTACCGGCGGCGTTGCTGGCAGCCCCGAGGACGGCGAAGAAGACGGCGAGGACGAGCATGGGTGATCCGTGCCCGGGTGGGGGCGGCCCCTCCCTGAGCTGGGAGGATTGCCGCCGATCGGAGCAGGCGGCCGGGGCGGGTGCGCCCTCACCCCCTCTTGGAGACGAGCCGGCCCAGCGGGTGCGCCTCCCCGCCGAGCGCCCGCCGCACCGCCTCCCACTCCTGACTGCCAACGCCGAGGACGTGGCGCAGGTACGCCGTGGTGACCTCCTGCACCAGGGCGACCCGGGCCGGGTTCTCGTCGGTCGTCTCGGCCACCTCGTACCCCGAGATCCCGCCGAGGAAGTGCTCCGCCCCGAAGAGCGTCAGCAGACTCTTCTCGCCCGGACTCAGTACGTACGGATCGGCCGTCCACTCCGGCCCCCGCACGGTCAGCGGCGAGGCGTCCCGGTCGCCCGCGACCACCAGCGCCGGGGCCGTCATGTGCGCGAACTCCGGGCCCCGCAGCCAGGGCAGGTTCCCGGCCGCGAACGGCGTCAGGGCGTCGCCGCCCCGGCCCGCCGTGGCCAGCAGCACCCCCGCCCTGACCCGCGGGTCGGACAGGTCCTCCGCCCTTCCCGTCTCCGGGTCGAGGACGCGCAGCCCCAGCAGCACCCCCGCCGTCTGCCCGCCGAAGGAGTGCCCCGCCACGGCGATCCGCTCCTGGTCGACCCGCCCGGCCAGCCCCGGCACCTGCCCCACCAGCACATCGAGCCGGTCGAGCACCCGCCGCACATCCTCGACCCGGTACCGCCACAGCCCGGGCCGCCGCGGATCGTCCGCCGCCAGCCCCACCGTCTTCGCGTCGAGATGCGTGGGCTGCACCACCACGAACCCCCGCGCCGCCCAGTAGTCGGCCAACGGCCCGTACCCCTCCGACGACGCCCCGAACCCGTGCGCGAACACCACCACCGGCAGCCCCCGCCCCGTGACGGGCGCCGACACCCGCACCCGCAACTCCTCCCGCCGCCCGGGCACGGACAACCCGAGCGGCTTCACGGAAACAACAGGAACCGGGACGGGAACGGGAACAGGGACGCTGTCCATATGAGCCACTTCTCTCCACCAGCGATCAAAAGGCCGGGTCGGTCTGTCCCGAGTTACGCTAAAACCTGACGCTGACGTCAGAGGCAAGAGAGGCACCGGACCCATGATGCGCATCGGCGAACTCGCCACCCGGACCCACGTCAGCGTGCGCGCCCTCCGCTACTACGAGGAACACGCCCTCCTCACCGCCGAACGCACCCCCAGCGGCCAGCGCCACTACCCGGAATCCGCCGTCGCCCGCGTCCACCTCATCCAGCAGCTCTACGCCGCCGGCCTCTCCAGCCGCACCATCCGCGACCTCCTCCCCTGCGTCCTCGACGGCCGGGCCACGCCCGAACTCCTCCACCGCCTCACCGCACAACGCGACCACCTCACCACCAAGCTCGCCGCCCTCACCGCCACCCGCGACACCCTCGACAGAGTGATCGCCAACGCGGAGACCAGCTTGCGAACGGGGGAGGCGTGCGGCGGCGGGGAGTGACCGGCCCGCGCTCCGGGACTCGGGCCGGGGCTCAGGGCCCGGACGGCCCCCGCATCTCGTCCAGGCCGACGCCTCGGCGGGGCAGATGCATCCACCCCTCGACCGGGGCCAGGGCCCGCTCGTCGCCGGTGGCAGGCCCCTCCGTCAGCCCGAGCGCGACCGCCCGCGCGACGACGGCGGAGATCAGCGCGTCCAAGGCGTGGTCGTCGGCCACACACCGCCGGCGGGCCTCCCCGGAGAGGTCGAGGCCCAGTCCGGCCTCCAGAGCGGCGAGGACGCGGCCGCGCGCCGCCTCGGCGCCCTCGCCCTTGCCCTTGTAGGTCCCCTCGGAGGCGATGCCCCACATGATCAGCGCGTACGCCGGATACACCTCGGCGACGGCCCCGGAACCGTCACGCGGCACCGCCCGCCCCTCCTCGGCCAGCCGCGCCAGCAGACCGGCCCCACGGATCGCGAGGACGCCGAGCTTGTCGACGGAGACCGACAACGGCCGCCGCCTCCCCGCCCCCGTACGCTTCCACGCCACGTCGTCGGTGAGGCGGTGCGTGAAGGTGTTCCCGAGCCCCGGACGTCCGTCGGCGCAGGCCTCGTGGTGCGCGAGCGCCGGCAACTCGGCGCCGCTCCGATGGGCGGCGACCAGCTCGGCGAAGGCGACCGGCCAGCCCAGCGGCGCGTCGATCCCGCTCTTGTCCGCGCTGCGCATCGCCGCCAGCAGATCGTCGTCATCCCTCGCCGGGAGCAACTCGACCACGGCCCGCCGCCCCCACGTCACACGGCACACCCCGGTCGTCCCGGTCCTTCCGGCCAGGTCCACCCCGACCGTCACCCGCGCTTCCCCACCGCCACCCACGCCCCGCTCAGCCCGCACCTTCGCTCTTGCCTTCGTCCTCGGCCCTGTCTCCGCGCAGGCGCCGCGCCCGCTCGGCGATGCCGCTCGCGAGCTTGTCCCGTACGGTCCCGGCCCGGTCCAGAGTCTCGTTGCCGACGGCCCTGGCGGCCGCCACGCCCATCGCCCCGGTTTCGAGCGCCCGGTCCCTTGCCTGCACGGCGGCCTCCCTCCACCGCCTCGCCTCGGTGTACCGACGCCCGGCCCGGTCGGCCACACGCTCCTGGAACTCATGGACGCCGACCACGACCTGGTTGCTCGCCTCGACCACGGCCGGGGACTTGGCCGGGTGCAGCAGCACCTTCGCGTTGGCCGCCCCGGCCGCCACGTTCATCCTGGTCACCAGCCGGTCGGTGCACCGCAGGATGAGCTCCTGCCGGTCCCGCCGGGCCTCCCTGAGCCCGAGGCGATGCCCGTTCAGCTCCTCCGGCGACACCTCCCGCACCCGGTCGAGTTCGAGCACCGCCACCGCGTCCTGCAACTGGAAGCAGCGGGCGAGGACAGCGAGCCACTCCCGCACCGCCGGCTCGGCCTCACGCACCGTCGCCGCGAGTTCCCCGATCTTGGCCTGCCGCTCCATCTTCTCCGCGAGCGCGTCCAGCTGCCGCAAGGCGTACGCCTGGGTCTCCGCGATCGTCGCCGGCCCGCCCTGCACCTTCGACCACGTGACCTCGTCGACCCCGCCCCGCTGCCGGCGCACGGTCATGGCCTCCTCGATGACGAGCCCCCTACCGATCATGCGGGACAGCACCCCGTCCTTCTGGGCCCGCAACACGTCGTCGACCTTGGCGTCGATCGCGTCGAGATACTCGCTGATCTCGTCCATGGCCTGCTCCATCGCCACCTGCGCCAGCAGCTTGGCGACGTTGGCGAGAGCTACCGGGCTCCCCACGACCGACCGGGACCCCCGGGCGAACTCGACGAACCCCTTGATCTGCCCCCGGTCCCCCTTCAGCACACCGGTACTGACCCCCGTCGCCGCGCTCTCCCGCAACCCGTACTTCTTCACCTGCTCCGCCGACTCCGCCGTCAGCTTCACCCACCGCCCGGACACACCGGCATCCCCGTCCACCCCCTCCTTCACCACCGCGGCCCCGGCCCCGACCACCCCCTTGATCCACCCCGACCCGACCTTCCTCCCCACCAACCCCTCCGAGACAAGAAACCGCTCGACGTCCTCCCGCCCCCCGATCACCGCCAGCCCGTCACCATCACTGACCAGCTGAACCTCGTCCTTCATCGCCCACCCACCCGCTCCGGAGCTCTCCTGAACGAACAAGACTATCCACCCGAACCCAACAGGGGTCCCGTTCAGCCTTGTTGAACAACTCCCGAGAACGACAAAGGCCCAGATCAGAAATCCTCTGACCTGGGCCTCACCGGAGCCGCCTTCGGGATTCGAACCCGAGACCTACGCATTACGAGACCAAGAGTGATCGTGTTGCGTACTGCCTCGTCATGCTGTCCGGTGACGTTTATGCTGATCAGAGCATGTGCAGCAGGCTGACCTGTGCCACCCCGTGATGCCCCGCCCAAAGGCGTCTGTCCACCGGCTGTCCACCGGCGGGGAAGCCGAAAGGGTCACCGAGGGCACTGCGCGGCCGCAAGCGCAGCCTCTGACGAGACCAGACGGGCACATATAGGCGCTTGTCCGACCTCGACAAAAGCGCCTTTGCCCCCGAGTTCCTGAGCTTTCCTGCCGAGCGACGCCTGCACAAGCCAGAAATGTCGGCGACCCATTGCCAACACCCGCCCACCGACCTCCCCGAGATCGTCCGGCTGCTCGGGCTGCCGCCGTAGATCGAGCAATGCTACGTACAGATCAAGGACGAACGCGGCTGGGCCGATATCCAGGTCCGCTCCGACCTGCAACCCTTCGCGTTTCAGGGTATGTGACGCCGCCCTGCGGCGTATTACCAAATGGGACGCCATGGAGGGATCGAGTCTCCTGCCAGGGTTCGGGTGATGGCCGCGAGCTCAGTTCGTGGAACCTGCAGACCGACCTCATGGAGTTGCTTGGTCAGTTGTGCTTCCAGTTCGTGCAGGATCCTTCCCGCTACGACCAGGTGCTCCAGCGCTTTCGCCGTCAGCACGACGAGCTTGCGTCGGCCACCGGCGGGGTGCGGTTGGCGCTCGACGTATCCCCGCTTCTCCAGGTCGTCGAGGATCTGGCCAGCGGCTTGCTTGGTGACCCCGAGTTGCTCGGCGAGTTCACTGCTCGTTGCGCCGGAGCCGCGGAGCACCTGAAAAACCAGACCGTGCATGGGGCGGAGTTCGGCGTAGCCGGCGGAGTCCAGGCGGCTCACGAACTCGGAGAGGACCAGTTGGAAGGCCATTCCGAGCAGGAAGGTGAGCTCGGTGCGCTCAAGAGGGTCGTTGGTCTCCATCGGTTCATCTTGACACACGCCTGTAAAGTAGCTTTACTCGCTGCAAGTAAAGAAGCTTTACACAGGAGGATCCATGTACGTGGTCAGCGAGAGCGAACAGCGGACGACCACCACGCCCGCCGGTGCGATGTTCGGCCTGGCAGGCCCGAGCCAAGGTAGTGCCGAGGTCAGCACTTGGCGGGTGGAACTCGGCGCGGATACATCCACCCCGGTGCACATCATCGACCGTGAGCAGGTGTGGATGCCCTTGTCGGGTGAGTTCGAGGTCGAGGTGGACGGCAAGACCGAACAGGTCAAGGCCGGCCAGGCACTCGTTCTTTCCGCCGGCGCGGTACGGCAGCTCAAGGCCGTCGGCGGCCCTGCTGAGGCGTTGGTCACCATGGTTGTCGGAGGTAAGGCCATGATGCCGGGCAGCGACAAGAAGATCCCGCTTCCCTGGGCGGAGTGACATCACTCCCTTGAGCAGCCCGACCAGGCCCCCCGATGGATCTGGTCGGGCTGTTCGCTGCTCCGGGCCTTGTCCCGCTGCCCCGGCGTGAGCGCGAAGCCGGAGACGTCAGACATCAACCGCAACTCCACCAAGGACAGTTATGGACCCCGAAGTCAGCAGCGTGAGCTGTACTGAGATTTGTGGAGTCCCTGATGCCAGGGTTACGGTCCTGGCGAAGGAGATCCACCAGCACCATGCCAGCACCCCGTAAGTACCCCGATGAACTTCGTGAGCGGGCGGTCCGCGAGGTCCGCGCCACCGGCCGCCCGATCGCGCATCTCGCGAAGGACCTCGGCATTCACAAGGAGGCCCTGCGCGGCTGGGTCCGCCAGGCAGAGGCCGACTATGGCGAACGCAACGACCGGCTGACCACAGCCGAGCACGACGAGCTCAAACAGCTCCGCAAAGAAGTAGCGGAGTTGCGGCGGGCCAACGAGATCCTCAAGGCCGCCTCGGTGTTTTTTGCCCAGGAGATCGACCGTCCCCGGACGAGGCCGAGCAGGTGATCGACCACCTGCGTGACAACGGTCTCGGGGCCGATCCCGTCTGCCGGGTGCTGGGCCTGTCGCCGTCGACGTACTTCGCCCGCAAGAAGCGGCCGAAGTCGGCCCGTCGGCTCCGCGACGAACAGCTCGTGCCGGTGATCGAGCAGGTCCACGCCGAGTCCGCCGGCACGTATGGGACCCGTCGGATCACCCGCGCCCTGCGGCGCAAGGGTGTTGAGGTGGCCCGCTGCACCGTCGAGCGGCTCATGGCCGAACACGGACTGGAGGGCGTGATCCGTGGCCGGCGGCGCCGCACCACGATCCCGGAGCCGTCGGCGCCCCGACCGCCGGACCTGGTGGACCGCAACTTCACCGCGGCGCGGCCCGATCAGCTGTGGGTGGCGGACGTGACATATGTCCGCACGTGGTCGGGCTGGGCATATGTGGCGTTCGTCCTGGACGTGTACTCACGGATGATCGTCGGCTGGCAGATCGCCGACCACATGCGGACCGAACTGCCTCTGGACGCCCTGGAGATGGCGCTCTGGCGCCGACGCATCAAGAAGGACTCCGGCCTCATTCACCACAGCGACAGGGGCTCGCAACATGTGTCGATTCGCTACACCGACCGACTCGCGGACATCGGCGCCTCCGCGTCGGTCGGTTCCGTCGCGGACTCGTACGACAATGCCATGGCCGAGGCACAGAACGGCACTTTCAAGGCCGAGCTGATCGAGATGCAGGGCCCCTGGAAGGACCCCGCCCAGGTCGAACGGGCGATCTTCCAGTGGATCACCTGGTACAACGAAGAACGCCTGCACTCCGCGCTCGACTACGTGCCACCCGCCGAGTACGAACGCGGCTTCTGGCAGCGCCAGGAACGAGTCCCCCAATCCGCCTGAAACAAGATCACCGGACTCTACGAAACTCGGGGCAGCTCAGCCGACCGAGTCCGGAGTGATGCCGTATATCTCGCTTCGAGGCGAGCCCGGCGCACCGCACACAGGCAGTACGCCCGGCGCGGCCCGGTCGATCCGCGGCAAACCATAAGGGAGTTGCTGCGCCGGGGCGGTGAGCCGGCCGGCCTGCGCCGCCGCGCACGTACCGAACGATCCCGGCAGGTGTCCTGCTGGATGTGAACGCGGCCCGTACGCCGACCTGCTGTTGCTGTTCGCGCACGCCTCCACGCACGGTGGTGCGGAAGAGCGGCGCCATACGGAGGCATTCACGATCAGCTCCCGGCCAACCCGGCCCCGACCGGCCACCGTCTGGTCCGGCGTGATGCCGGGCAGTTCGCGGGCGACAGGTCTGCATAACGTGAATGCGCGAGCACGGTGCCATTGCCGAGGCCGGCAGGAGCAACCACCCGGGAGGGGTGCGATGTTCGACAGCGATGGCGTGGGCGTCTTCCGCGGGATGGACGTCGGCAAGACGGCCCGTCACGGCCACGGCTCACCCCGGCCAGGGCCTCGGCACTCGGACACTCCCAGGTTCACTGCGCCAAGGGGGTTCCTTCGGCGTGAGCAGTCCTGAGGAGTGTTCAGCGTGGAGCATCGTCCACGGTCACGACGCGGTTCTGGTAGGCCCACACGGCTGCTTGCAGGCGGGACTGCACACCGAGTTTGGGCAGCATACGGGCGAGATGCGACTTGACGGTGGTGACCTCGACGACGAGTGCTCCGGCGATCTGCTCGTTCGACATACCCTGCGCCAGTAACAGCAGGATGTCTCGCTCGCGGGCGGTGAGGACGTCGATCCCCCGCGTCGCTGTCACAGGTCGCAGGCGCCGTCGTTCCACATACTCGGCGACGATACGGCGGGTCAGAGTGCGGTCGAGAGTGCCGTGTCCCGCGGCGATATGGTGGATCGCTCGCAGAATCTCCTCGGGGTCGGAATCCTTGAGCAAGAACCCGGCGACCCCCGCTTCCAGCGCCCGGAAGACGTAGTCATCGATGTCGAAGGTGGTGAGGATCAGCACCGGGACGGCTGGAGACGCGTCGGGGCCGCAGATGCGGGCCGCGACGTCGATGCCGTCCATCTTCGGCATCCGGATGTCCAGGCACGCGACGTCCGGAACCAGTTCGGTGGCCAGGTCGAGGGCTTCCGCCCCGTCCGCGGCGACACCGACGACCTCGACGTCCTTCTCCGCGTTCAGCAGTGCGCTCAGGCCGGCGCGGACGAGAGGCTGGTCGTCGGCAAGAAGGACTCGGATCACGTGAACTGCTCCGGGAGGTGGTGCCCGCTTTCGCGGGGGATGCTTATACGGGTCTCCCACCCGTCGTCGTCGGTCGGGCCAGCGCCGAAAGATCCGCCGATGAGGGCGGAGCGCTCTCTCATGCCGATGATGCCGTAGCCAGTACCGCGTGAAGCGGGACGGGCCTGTGGGCCGGGCGGTGCGTTGCGGACGGTGATTCGCAGCGTGCGCGGGTCACGGTCGTCCACGGTGACGACACAGGGGGCGCCGGGCGCATGGCGTGAGGCGTTCGTGAGCGATTCCTGCACGATGCGATAGGCGGCCAGCTGACCCAGCAGGCTGACCCCTGCGCCCGGCTTCCGTCGTTCATCGCTGCGCAGATCGAAGTCGACCTGGGCTCCGGTGAGACGGGCCGTCGCGATCAGGTGGGGAAGAGTGGCGAGGGTTTTGACGCCCTCGTCTTGGTGACCGACGTCGCGGAGCAATCCCACCAGACGACGCAGGTCATCCAGGATCGCGTTGCTCTGCTTGCGGATCTCCAACGCTCCGGAGTGGGCTTCGCCCGGTGCCGAGGCGGTCTGCCGAGCGACGACCGAGGCCATCAGCGAGATGCCGGACAAATGGTGGGCGGCGATGTCGTGCAGCTCCCGCGCCATCGCCGCCCGTTCCAGAGCGATCGCCTCACCGATCTTGGCATCGCGCTCACGGGTGACCGCCGCCAGCGTTTCCTGCTGCGCGGCCCTCGTCGCGCGTTGCGCGGCGATCACGGAAGCCGGCAGCAGTGGCAGGCCGACCACCAGGGCCGCCTGAAGCAGCGCCTGCATCACCAGGCCCCACCCGCCGGTGCGCCCGTCGGCGCTGCCGTTGACGAAGTGGGCGGTCGACACCAGTACGCCCGAGGCCAGGGCCCACCGGCACACATCCCGCCAGGCCCCGGTCAGCCCGGCCAAGAACGCACCGACCAGAACCGGCAGCGCGGTAACAGTGAACAGTCCGCTGGGAAACACGGCCGCCAGGACCAGGCAGAGTCCGGCCACGCAGCCCAACGTGGCGGTCACCTGATGGCGGCCCCACAGCAGGGCCACCGATTGCAGGACGAGCGTCACGGCCGTCCCCCACCAGGCGGCCATGCCGAGTGGAGCTCCGGTGAGTGACGGGTCATCACGCGCCAGCAGCGCGATGATCCACAGGAGGGCCAGCGCGCTCAGCGCGGTGGTGACAGCGGTCGCTGCGGAGCGGGTCATGCTGGGGCGCCGCGCGGTCGTCACGGCTCGATCATAGTGAGGTCCCGGTCATACCCCGCGCGGCGGGCGAGCGGCGACGCATCCCCGTGGTCCGGCGGGACGGCCGGGCCGTGGCCGAGACGGCCGCGGGTGGTGATCACGATCACCGCCGCGGCAACAGAGGCACCGGTCCCCATCGCGACGAGGGCGAGCTCCCCGTCCAGGCCGGGAAACATCTCGGACCACATGACGGACGCGAAGGTGTTGACGCCGACATGCATGAGCATGGACAGCGGCAGACTCTGCCCGGTGCGGTTGAACACCCACGACATCACGATGTTGAACGCGACGCAGAACGTGAAGAAGGCCAGAGGCCGCGTCCAGGACGCCTCGGGGTAGCCGCCCCACTCGGTGAGGAACAGCGGGAAGTGCCACACACCCCACAGCGGGCCCAGGACGAAGGCGGCGCGCAGCGGCGAGAACCGGCTCTGCAGGCGGGGAAGGGCGAAGTCGCGCCACCCGGGTTCCTCGGCCAGACCGGTCGTGATCATCTGGAACAGCAGCATCGGCACGAAGGCGGTGAGCGCTGCGGCCGAAGGGGCGGCGACCTGCCCGCCGGAGAACGCCAAGCCGGTCAGGAGCATCCCGGCAGGGACGCTGAGCAACGTGATCGCGTACCAGCGCCCGCCGACCCGCCACCGCCACAACCGGCGCGTCCAGGCCCGCAGACCAGTCCGGCCGTCCACCAGCGCCGTCATCGCGAACGCGGCACCGATCGGCCCCAGGTAGGCGCCCGGGAGGACCCCCAGCACTTGAGTGGTCCCGAGAATCGCGGGAAACCGGTAGTCCCAGATGCCGAGGCCGTTCTGCGACAGGATGTACGGCACCCATGCCACCCAGCTCAGCCCGTTCGCGAGGAGGAAGAAGTAAGTCAGCGGACGCGCTCGCGCCATCGCTCGGAGCCGTGCCGGGAGGCGGTCGGGGACCGGGGTTCGGGGGAGGCTGGCTCTGTTCTCTGTCATGACGGGAACGCTAGGTTTCCTCGCCCGACGGGCTCTACGGCCCGATGGTTGCATCAAGGCAGTGCATCCAAAGGATGCAAACCCGCTCCGCGCGGAGGAGTGCGACGCGTAGGGCGGCCGCGGGAATCCTCCTCACATCGAGGCTCGGGCCGGTGGTTCCACACCCGTCATGCGGGTGCACGAACGTCGGGGCCTCCGGTCCGGGGCACGGATCGGCACAGGAGACGCGTGAGTAGGGTGACTATTTGATCGATCATTTATCGGTCTCTATTCGGAGGGCAAAAAAGGGTGGAAAGAACGGAAAAATAGGTCAGCGAGTGACTGTGGTCACCGGCGGCAGTCGGGGCATCGGCGCGGCGATCTGCCTGCGACTGGCGGCCGAGGGGCACGATGTGGCCGTGGGGTACCGGTCGGATGCCGAGGCTGCCGAGGGCGTGGCCGAAAGGGTGCGTGCGCTGGGGCGGGCGGCTGTGGCAGTCGCGGTCGACACCGCCGACGCGGCAGACGTGGACCATATGTTCGATATCGCCGCCGAGCGCCTGGGGCCGGTCACCGGGCTGGTGAACAACGCCGGCGTGAGCGGGCCGGTGGGGCCGCTGGCCGAAGCCGATCCTGAGGGGATGGGGATGCGGCAGGCCCTGGAAGTCAATGTTCTCGGATACCTGCTGTGTGCCCGCCGGGCCATCGGCGAGATGACGGCGGGCGGGGCGATCGTGAACATCTCCTCCGCGGCTGCGACCCTCGGCAGCCCCCGGCACCTACGTTCACTACGCCGCGGCCAAGGCCGCCGTGGACGCCATGACGGTCGGGCTGTCCAAGGAGGTGACGGCCGACGGCATCCGGGTCAACTGCGTCGCTCCGGGAGCGATCTGGACCGATTTCCACGCCGACCCGCAGCGGCCCGCCAAGGTCGCGGCACTTGCCCCTATGGGCCGCGCCGGCCAGCCTGAGGAGATCGCCGGAGCGGTCGCCTGGCTGCTCTCGGACGACGCCTCCTACGCGACCGGCACGGTAATGCGGATCGCCGGCGGGATGTGACCACGGACGACTCCGGCGCCTCGGACAAGGCCGGCGGCCCCTCTCACCGTGAGTCCGTTCCCATGCAGGGCCGTACCAGCGCTCCCGTGCGACTCTCGAACGCGATGCTGGGCAAGGGTGTCGAGCGGAGAGGCTCACTGCTCGGGGGAGCTGGTGCGCCCTGACGGTCATAGTCAACCTGCGGTGCGGAGGCATGAACACCCAGCCCGCCGGTCGCGGGCTTCTTGCGCGAGTCCGGCGTCCGGCACGTGCGCGCGTCAGCGTGCTTCGGTGGCCCGGCGGTAGGCGCTGGGCGTGACGCCGCGGGTCCGTTTGAAGGCCACGCTGAACGCGAACGGGTCCGTGTAGCCGACGGTGCGGGCAATGGACGCGACGGTAGCGGAGGGGTGCTCGGCCAGAAGGTCCGCGGCGAGTGTCATGCGCCAGTGGGTGAGATAGGCCAGCGGCGGTTCACCGAGTAGCTCGGTGAACCGCTTGGCCAGTGTCGAGCGGGACACCCCGGCACGCCGGGCCAGCGCGGCCACCGTCCAGGGCGCGGCCGGTTCGGCGTGCAGCAGGCGCAGGGCCTTGCCGGCCACCGGGTCCTTCTGCGCGGACCACCAGGCCGGGGGTCGACGACCGGGCTCGTCGAGCCAGGTGCGCAGCGTGCACACCAGCATCCAGTCCAGGAGCCGGTCGAGCACCACCTGTTGGCCCGGTTCGTCGCGGGAGACCTCGACGGCGAGGTGATCGAGCACCGGGTCGCCGTCGCCGCCGGCGGGTACGCGCAGCACGACGGGCAAGCTGTCCAGCAGCCGGCGGCCGATCTCGCCGCTTACCGGGTAGGCGCCGATGACCAGGGTCGTTGTGCCGTGCCCCGCCCCGTCCTCGCCGGGTTCGTGCCAGCCGAGCCGGTGGCGGGTGCCGCCCTGCTCGGGGGTGGCGCACTCCGCGCTGCAGACGAGGGGTTCGACGGTGGTTGCCGGGTCGTCGACGAAGGTGAAGGTCGCGGGGCCGCGTACCACGACCGTGTCGTGGGGGCCGAGTCGTTCGGGCGGATAGCCGTCCAGAACGATCCAGCCGGCGCCTGTGAGAACGGTGCACAGCGTCAGTGGGGGCCCGTCCACGAAGTGCAGGGACCAAGGTGGGGACAGCGTCGAACTACCGAACAGTGAGCCGTGCGCTCTCACGCCTCGAAACAGCTCGCTGCTGATGTCCACCCCACCAGAGTAGACGATTACAAAGGCAAGGCGGCTCTTCACCCATGGGAACGTCCGGGCGGCCCGTGTTGAGTGGAGCCATGAACACACACACTTGTCTTGTGGTTGGCGCGACCGGCCGGACGGGGCGCCGTGTCGCAGCCCGGCTGCGACTTCGCGGCATCCCGGTGCGCGCGGCCTCCCGGTCCAGCCAGGTCCACTTCGACTGGTCCCAGCCGGCTGGCTGGGACGCCGTCCTGCACGGCATCTACGCGGCCTACGTGGTGCCCCCGCCGGTGCCGGGCCCGGTGCACGCATTCGCGGCGCGGGCAGCGGCCGCCGGGGTGCGACGGCTGGTGCTCCTCTCCGGCCGCGGTGCGGACGGCTGGGGCGGCTCCATGTTCGGGCGCAACATGGTCTCCGCCGAGGAGGCCGTCCGCGGTGCGCCTCTGGAGTGGACCGTGCTGCGAGCGTCCAACTTCGCCCAGAACTTCGGCGAGGACGTATTCCACGCACCGCTGCTCGCCGGCGAACTGGCGCTGCCGGCCGGGGACGTTCCCGAGCCCTTCGTCGACGTGGAGGACATTGCGGACGCTGCAGTCGCGGCACTGACCGAGCGTGACCGGCACGTGCGGCAGGTCTACGAGCTGAGCGGGCCCCGCCCCGTCAGGTTCGCCGAGGCCGTCGAGCTGATCGCGCGGGCATCCGGACGGACGCTCACCTACCGGCAGATCACCTGTGACGCGTACGTGGCGGAGCTCGTCGGGCAAGGCGTAAGCCGGCACGAGGCCGACGAGGTCGCCGAAATGTTCGCGTTGATGGCGGGCGGCTCGGTCTCCGAGACGACCGGCGACCTCACCACCGTGCTGGAACGCGCGCCGCGAACCCTCGAGGAGTACGTCGTCCGCGCGGCCGCTGCCGGCGTCTGGAATGCCCCGCAGTGAGGCGCCGACCACACCCCGGCCGCTCACGGACCGCATCCCCGCACACCCACACCCGCGAAGACCTCCGAAACCCGGCCCACACCTAAGGACGTACCGCCATGAGCACAGACGAGACCTCTCGCACCCTTCTTGTCACCGCGCACCCCGACCCCGGCTCCCTCACCCACTACATCGCGGAACGTCTCAGCACAGCCCTGCGCCCCGGCGCCGTCGAGGCCGCAGACCTGCACCAGGAGGGCTTCGACCCCCGGTTCACCTCGGCGGACCGTCGCGCCTACCAGGAGGGCGGCGGCCACCCACCCGACGTGGTTCGCGAGCAGCAGCGCCTGGATTGGGCGACCGACCTCGTTCTCGTTTTCCCTGTGTACTGGTGGTCCGTACCAGCCCTCCTGAAAGGGTGGATCGACCGGGTCTTCGTCAACGGCTGGGCCTTCGAGTACGCCGCCACAGGAGGAGTACTGCCCAAGCTCCAGCGACTCACGACGCACCTGCTACCGATAGCAGGCGCCGACGCCGGCGCATACGAGCGGCACGGCTACGAGATGGCGCTGCGCACACAACTCACGCACGGTCTCATCGACTACGTCGGCAGCCAGCGCGGAGCCACCGCCTTCGTCCACGACTCCGAACAGCCCTCCACCGGGGCCGCCGTAGACCACGCGGTCCGCACGCTGGCCAGCGCCGTCGGAGCCCCTGTTTCCCGTTCCTGACCCGGGGCCCGGTGGAAGTGGGCCGCAGTGGCTATCCGTCCCTGCCGGGTCCGAGGTGTTCGCCCAGGAACCGCTCCACCGCGCGGTAGACGGCGGTCAAGTTCTCCGGGTTCTCGATGGAGTGCCCCTCGTCCCCCATGAGGATGTACTCGACGAGGGCTCCACGCGCCCGGAGGGCATGGACCATGTTGTCGGATTCCGCCTGCGCCACTCTCGCGTCGTTGGCGCCCTGGGCGATGAGCAGCGGTGTGCGGATCTGGTCCACCCGGCTGATCGGTGAGCGGGTCAGCATGTCGGCTTCCTGGTGCGGATCCGCAGGGTCGCCGACCCAGCGGAACCAGTTGGCGGCAAGGGCCGGCCGGACGAACTCCGGCTGATTGCGCAGGAAGTTCGCAAGGTCGGAGACCCCGAAGATGTCCACGGCGGCGGCGAAGACGTCGGGGGTGAAAGCGGCGCCCACCAGCGCTGCGTAGCCTCCGTAGGAGCCGCCGAGGATGGCCACCCGGTCCGGGTCCGCGTATCCCTGGGCAACGGCCCAGTCGACCCCGTCGATCAGGTCATCGTGCATCTTGCCGGCCAGCTCCCCGATACCGGCCTTCATGAACGATTTGCCGTACCCCGTGGAGCTGCGGAAGTTCACCTGCAGGACCGCGTAGCCCCGATTGGCCAACAGCTGGACCAGAGGGTTGAAACCCCAGCTGTCCCGGTCCCAGGGGCCGCCGTGCACGAGCAGAGCCAGCGGCAGTCGGTGCGGCTCCACCCCGAGCGGCAGCGTCAGGTGCGAGGGAAGCGCAAGACCGTCCCGAGAGGTGATCGTCACCGGTGTCATAGACGCCAGTTGCTCGGGATCCAGGTGACCACGGGGACGGAACAGGAGCCGGCTCTCGCCTGAGGAATGGTCGTAGTAGTACGCGGCCCCAGGATCGCGGTCGTGGGTGAAGCTGACGACCCACCGCTGCCCGGTCTCGTCTGACGAGATGTCGGCCAGGTCGCCGGCGGACAGTTTCTCCAGGTTTTCCAAGACCTCGGCGAAGTGCGGGTCCAGCGCCTTGATCACCTGTCGTTCCCCGAGATATCGAACCCCGATGAGTTCACCGGTACGCCGACTGAAGATCAGAGGGGAGGGCAGCGAGGGAAACACGCGGGCCCGAGTGTCCAGGTCGTAGCGCGGGTGAGAGTCAACCACAGTCTCTTCACCAGTCACCGTGTCCAGCCGGACCACACGAAGCCTGTCCGAGTCCTGGTACGAGCCATGGAGCACACCACTTCCGTCAGGAGTGACCTCCAACGGATAGACGCCCAGCGGATAGTCCCCACCCTCGAACCACGCCAGGTGGCACGAGGTCTGCGTGGACTCGTCCCACCGTGAGAGCCGTAGGTCGCCTCGTTCGCTGACCTCGCTGGTGAGGGGGCCCGCACTGCCGCCGTAGAAGAGAGTGACGGCCGCGCCCGCGGTGTTCTCCGCGAGCATCCGCAGGTCACCGGTGGCGATATCCAACTCGAAGAGGTCGAACACAGCGGGATTCCGGCTGTTGGAGGAGAACACCGCCTTCCCCGGCCGAGAGGTAGGAAGCTTCAGATCTGTGATGCGCGCACCGGGAAACGGCGTCAGGTCGACAGCCGCTGCGTCCGGGACGTCGAGATCGACTCGGTACAGGTGACTGTTCTCGTCGCCGCCCTGATCCCGGGTATAGAGCAGCCACCGCGGATCATCCGTCCAGTGATAGCTCAGCAGGTTGCGGTCCTCAGAGGTGACCCGCCGCGCCTCCTCCGGCGCTTCGACACTCCCGACCCACAGGTTCAGACGGTTCTCCCAAGGAGCCAGATAAGCAATCTTTGTGCCATCCGGCGAGATAGAGGCCCTCGAACGCCTTGGAGGCGCGAAGAACTCCTCAACGCTGATGATCGTCGGCAATGCCATATCAGTCCTTCCCGTTGTTACGCCGGACAGCAACGGCAGAACCCCGGCGGTGGCAAGGAACCTGAGCGGGTACGCAACCTTGAGTCGCCGCCTTCCCGCAGCCACAGCTGTCACTTAGTGACAGTGTCACTAAGTGACAGGTTGTGTCAACTGTCGCTGCGGACAGTCGGCCAGATACCGGGAGACGGTGAGCCTGCACGGCATGGATGCCGTATCGACTCTCCGGCGGGCCGGTCGGGCCGGAGGTTCAGGTCGTCCCGGGCCAGGATCCGGTGGACGGTGGCAGCCGGCACCCAGAGATCGGGCCGAGTTCGCCCGGGTGCCACACGGGCGGCGACAGGTCATCTCCGAGGGCCGACCAGCGCGTGGGCGGTGATGCATGCCGACGGCCATCAATACAGCGGGGCAACTGGCGGGCGCAGCGTCGGGCGGGGCCAGGGGCCAGCCGGCGAGCCCGTCCGGGTCGGACGGGGCAAAGAGGGCGACGGCCGACCATGCGACGACCGGCAGCCAAGCATGCTGTGCGCCGAACAGGGCCGCACCCAGGGCCGCGAATCCGGTCAGCCCGGCCGCATTCCAGGCCAAGAAGCCGACTGTCGCAGCCTTCACACACCCCAGGCGCGAGCAGTTCCTGGCAAGGTTCCCACTCCCGCATGACCTCCGTCTCATCGCCACCGAGGGCCCCTGCCATCGGTCCGGCCAGCGCACCCACCCGGGCAATCGGGCCGCCGCTGATTTCCTCATGGTCGACCTCCTGTAAGGCGCCGAGGCGGCCGCGGGTGCACCCGCACCCTGATGCCGCCGGCAGGCGGGTCAAGGCGGCCGGTAAACACTCGACCAATTCGCCTTCCCCCCTGACCGCAGCCCCTCAGCCAGGCCGTGCGGGCGCATGCAGTGCGTGGCCGCACATGATCGCAGCGACGGCATGAAGCACCGGCCCATAGAAAGCGCGTCCGCCGAATCGGACGTCGCCGTGACCGATGCGAGTACACACGCCTCCGGACGGGCTGCGCGCAGCCCGTCCGGAGCGGATGGAGATCGGAAGTGCCGAGTCAGGTGCGCTTGGCAGGCAGCAGTCCCGCCACCTTCAGCCGCTTGTCGGAAGCCCGGGCGGCCCAGGCGACGACCAGGACTCCGAGGGCGAGGAGCGGGTAGCCCATGGCGATCTTGGCGAAACCCAGCGAGCCGACCTCGTCGGCCTGGTAGAGGTACTGCTGAACGGCGAATCGAGCACCGAAGATGACAGCCAGCACCAGGGTGGCGATGTCGTAATAGAGCCGCGAACGCCCGTCCGCACGCCAGACAACACCCTTACCGGTCGTCGCGTTCCAGATCAGTCCCGCCAGAGGCCAGCGCACCACCACAGAGACAACAAAGGCGACGGCGCCGGCCAGGCTCGCCCAGATGCCGATGAGGAAGAAGTCCTTGGCGGACCCCGTATACCAGGAGACGCCGGCTGCGACGGCTACGCCGAACACGCCGCCCAGCGCCGGCTGGATCGACTCCCTGCGCACCAGCCGCTGCGCCGCGATGCCGCCGGCGACCAGGAGAGCGGCCAGGATGCCGACCTTGAGTCCGCCGACGCCGTTGGCGACGACGAACACCAAAGCGGGCAGCGCCGAGTAGACGACACCTTTGACTCCGCCCGCCTGTTCGAGCACCGTCTCTTTCCCCCGACCTGCCTCCCGCGCGACAGCCGCCTCCCGGGAACTCGTGTCCTGCATAGCGATCCACACCTCTGGGTCAATTTAAGCGTCAGCAGCTTGCGTTGACGTCACTAAGTGACACATTGCCATTAAACGCCAGTCGTCGCCACCTTGCCTGATGTAACCCACGCCACAACCCCGCGAGATCTCGCACAGTGAGTCGCTCGTCATCAGGGCTGGCCGCCGGGTGCGCACGGCTGCTCGCCGTCGCCCGCCTGGAGAGGGCGCGAGGCCTCGATGGCAGTGCTCGCGCGGTTCGGTGGGAGCCTAGGCCCGAGGGGTCGTGCGCGCGCTACGGACGGCGATGAGGGGCAGCGACCAGGGGAGACAGACAGCGCAAGCTGGCGCGCGCCGTCGGCAACCCACCTACGACGTCGCCTGCTGATGTCCGGCTGAACGGAGAACCCAGGCCGAGTGACTGCGACGAAGGGTCCGCACGCCGCAGCCGACGACGACCCGCGCTTGCTATGGATCGAGCCGCCCGCGTGGCGCTCGTTCATCGGACCGGCCCCTCGAGGTCGCCGCCACGGTTCCGGACGGAGGAGCTACTCAGCGGACTCGATCACGTCGTGGTCCTGCCTGCCCGGCTCGCAGCACGGGCGCTGCGCACTGCACTAATCTGCCATGCTCTTGAACGGATGAGCTTCGTCGAGCAACCGACCGTCGCAGGCCCTTTCATCCAGTCGGCGAACGAGCCGGCGCGTTCGGCGTCACAGGTACTGCCCTTGCCGAGCATCGTTGTTCCGCACTCCGGCGTTCGGTTAGTCGAGCGTCCGGTTCCATGGAGTCAAGCCAGTGACGCTGGTCGAGCGGTCGTGTCAGGCAACGACGGCCAAGAGCCCCGGCCGTCGTTGCCTGATCCGTGCCCCGCTGCCCACACCCTGACGCTCCTGAGGAATATTGCACGTATGACTACTGTGTTCTCTCGCATCATCACTGGGGAGTTGCCCGGACTCTTCGTCTGGCAAGATCCGGAAATCGTCGCTTTCCTCTCCATAGCTCCGTTGCGGCCTGGCCACACCCTTGTGGTGCCACGACGTGAGGTCGATCGGTGGACGGACATCGACGGGCCCCTCCTGACGCGTTGCTTCGAGGTGGCCCAAGCCGTGGGGCAGGGGGTGCAGCGGGCCTGGAACGCTCCGCGCGCCGGGCTCGTCGTTGCGGGCTTCGAGGTACCGCATCTGCATATACACGTCGCGCCGGTCTGGGACATGACCGACTTCGATTTCAGCAAGGCCAAGCAGGAGGAAGACCCGTCGGCGCTGACCGGAGCAGCGGTAAAGCTGCGTGCCGCCCTGCTGGAACTGGGTTATGAACAGGCTCGGGGCTGCACCTCCGGAGCATGAACGATCACGCAGCCTGTCGGTATCCGTTCGAGGCTGACGTGGCATCACCAAGAGGCCGGGCCGCGTCCGCTCGCCACCCAGGAGCACACGGCTCATGCCCCCCGTTCGCCCTCAGCCCTCCACACCTGTGGGTGGGCAGTTGCAAGGATCGGCCAGCCAGGAGGGGCGGGGTGCGTCGGAGGCTGCTGACGTGGGTCCGGTACACCTCGCCCCCCCTCGAGATCGACGGACCACACGGACGACTCCTTGCCCAACTCCCCTCCCTCCGGCCCGGCGCCCTCGGCGAGGGGGGCTCGACGCCGTCCACGCTCTACAGCTCCTTCTGGGTGAGTTCGCAGACCTCCACCCCGCCCTCAGTACGCTGCACGGCGACACCTTCGGGCGCCGACTCGGCGGGTACCTCGGCGACGTGGACCGGGTCACCCACGGCGCCACCGGTGGCCGTGCGGACGGCATCGGCGATGAAGGCGAAATTCTCGTCACCGAGCTTCCGGGGATCAGTGCCGTCCAGAAGGCCTGCTCCCACGTACTCGTTGAGGACTCGTAGGGCGGCAGAAGCAGCCGCGGCGTGCAGACGTACCTGCAGGTCGTCGTGCTCACGTCCGAGCCGGGTCGCGATGACTGCGGCCAGTTCGTGTTCGACTTGATCGCATGCCATCAGCCAGGCCGTACGCAGGGCCGGCTCGGTATCACCCAGTCGCATCATCTTCACGCCCAGCCCGGCATCGGCCTGCTCCTGCGTGTCGATCTCGCTGACCAGCCGCTTCGCCTCCGTGGCAAAGTGCTCCTCCAGCGAGCGGTGCAGCGGCCAACTGCGCAGAGTGGCCAGTTCCCACTCCACGCTCTGCGCGATGATCGGCTCTGCACAGCTCTCCTTGCTGCGAAAATGGCGCCAGATGGTGCGGGTCGACAAGCCCACCGCCTCAGCGATCTGGTCACCGCTCGTCCCGTCGACGCCCTGCGCCCAGAACAGACGTGCAGCCTCCCGCGAGATCTCCAGACGTACACGACGACGACGCTGCTCGCTCATCCCACCGCGGCCGCGCCTGGCCGTGGCCTCTTCCTCGGCCATCTCTTCACCACCCGTTCCCATAATTTTCACCTTGCGCCACATTGGCACTAAGTGACGTTTTTCGCCAGTCTCTCGCGGCACAGCTCCAGCATTGCCCGGCCCCGATTCGCAGCCCGAGTGGACCGACAGGTGGATCTCGCCGCGAAACCGGTCAGGTGCGACGACCGCACCCCGGGAAGTGCGCCCGAACGACTTCACAGCACACTGCCGCGGACCCGAAGTCGACCGAGCCCCTCGCCGCGTGGCCACGCGGCCACGCGGCGAGCCAGGATGGCGGGACCCACTTGCCACACTCGTCACTTAGTGACATTGTCACTAAGTGACAGGATGGTGGTCGGCCGATTCCTTGCAGGGGTGACCTACGCGTGTGAGTGCCGCCCTTCCGCGTCTGCCCGCACCAGAAGCCAGGAGTACTTCATGAGGAAACGATCAGCCGCAACCGCCGCAGCACTGATCACGGCCTGCGCCGTGACCGGCGCCCTCACGGGGGCAGCCGTCGCCACGCCGGGCCGGGTGACCGACGGCAACCGAGCAGAGAAAACAGTTGTTGCCACGGCCACCCGTTCGGTGACCCATGAGGAGAATGAACGGGTGCCGGAGGGGGCGCGCTGGACCCAGCACTACTTCCCCTCCTCGGACGGCTCCGGGACCGAGCTGCATGCTGATGTGCTGCTTCCTGCGGACCTCCCCGAGGGCGCGAAAGTTCCCGTGATCATGTCGGCCGGCGCGTACTTCGGCCATTCGGGGGAGATGGAGGTCGAGGAGGAGCATGCCGGCCCTTCGGAGCGCTTCCAGGACCTCCTGGAGGGGGCCGACCTGTTCGGCAAGGGGTACGCCTTCGTCATGGTGGACACGCGCGGCTTCGGCGGCTCCACCGGATGCCTCGACCTCGGCGGGCCAGGAGACCAGGCCGACGTCAAGGCCGCGATCGACTGGAGCGCGAAACAGTCGTGGTCCACCGGAGCGGTGGGAATGTACGGCAAGTCCTTCGACGCCTACACCGGCCTCCTCGGCAACAACGCGAAGAACGACGCGCTGAAAGCAGTAGTCGCCCAGGAGCCAATCTGGGACCTGTATCAGCACCTGCACTCCAACGGTGTTCCCCGCCCGAACAGCGTGCAACTACCCACCAGCTACAACCGCATCGCCAGCCTGGCCCAGTTGCCGGACGAGGACGAGCACTACCGGACCAACTCCGCGTACGAGACGAAGCACCCCGAGTGCCTGGCACTCAACTCCTTCGGCCCTACCATCGGCGACCCGGAAGACCCTTACTGGAAGGACCGCAGCCCCGCCGAAAAGGCGAAGGGCACCGACACACCGCTCCTGTTCACCCAGGGCATCGCCGAGACCAACACCCTCCCCGTGGGGATGCAGGAGTTCCTCCACAACCACCGCGGCCCGCAGCGCGCCTGGATCGGCCCCTGGGACCACGTACGCGGCAACGACCGCACGCAGGAAGGGAAGTTCGCGATGGGCCGCGCGACCTGGTTCAAGGAGACAATGTCCTTCTTCGACGAACACCTCAAGGACATAGATCCCAAGGTCACATACCCGAACTACGCCGTCCAGGACAACCTCGGCAACTGGCGCGCCGAGAAGTCCTGGCCCACAGCGAACCGCTCCGCGAACCTCCGACTCGGCAACGGCTCGTACCTGGACAGCGGAGCAGGCTCACAGCCCACACCACCGGAAGAGGAAACCGGTCGTAATGCCGGAAGCTTCTTCATCTGGTCCGAACCTCTCAAGGCAGCCACCCGAGTCACCGGCACACCCAGGATCACCCTGACGGCCAGGGGTGAAGGCAACGTCATGGTCAAGCTGCACGACGTAGGCCCCGACGGAAACGCCGTCGCATTCGACGAGCGAGTCTCCCGCCTGGACCAGGACCACCTGAACATCAGCCTGAAGTCGACCGACTGGACCCTGCGAGCCGGCCACCGCCTCGCCGTGGAAATCGGTTCGGTACGAACCGGCGACTGGCTCGACACCCCCTCCAAGCAAAAGATCCAGATCAGCAACGCCCGCCTCCATCTGCCCCTGGACCACCCGGCCGAAGACACCGCCACCGACGGCGACCGAGCCCCATGGATCGACACCTACACACAGATCAACGCCGCGAAGCCGACGCCAGGCCCCGCCACCTTCACCGTGCCCCCAGCCGATACACGACGCTGAGGAACGCCACACCGCTTGGCATCCTGATCACGCCAGTCTGCGAGAGGCTGTCAAACCATCGACCCTGTCTCACTGCCTCCGAAGCAGATCCCTAAGGGCTGTCCCGTAACTGCTGGTCACAGATGAGATGATCTTGGCGTGGCTGGTGTGATCACTGCGTCGGAGCCGTCCTGGATTGCCCCGTTCAGCGGGCTGAGCCCGAGGCAGTTCGGGAAGCTGGTGACGGTGCTGCGTCGCGAGGGTGCGGACGCGGTCCGCAAGGGCCGGCCGTGGAGCCTGCCCCTGGAGGACCGGGCACTGCTGGTCGCGGCGTACTGGCGCACAAACCTGACCATGCGGCAGCTCGCCCCGCTGTTCGGGGTGTCGAAGTCGGCGGCGGACCGGATCATCGACCACCTCGGACCGATGCTCGCGCTCCAGCCCCGCAAGCGATTCGCCAAGGACACCGTGCTCATCGTGGACGGCACACTGGTCCCCACCCGGGATCACACCATCGCCGAGCGGTCGAAGAACTACCGGTACTCCACCAACCACCAGGTCGTCATCGATGCCGACACCCGCCTGGTCGTGGTGGTCGGACGGCCGCTCGCCGGCAACCGCAACGACTGCAAGGCATGGGAGGAATCCGGCGCAAAGGCCGCCGTCGGCAAGACCCTCACGATCGCCGACGGCGGCTACCCGGGCACCGGACTCGTCATCCCGCACCGCCGAGAGCGCGGACAGGCCGGACTCCCGGACTGGAAAGAGGAACACAACAAGTCCCACAAGCAGGTCCGAGCCCGCGTCGAGCACGTCTTCGCCCGCATGAAGACCTGGAAGATCCTCCGCGACTGCCGCCTGAAGGGCGACGGCGTCCATCACGCCATGCTTGGCATCGCCCGCATGCACAACCTCGCCCTCACCGGATAAACCGGCGGTCCGCACAACGGCCTCCCCCATACCCGAGGCGACCCGAAGATCATTTGCGGGACAACCCTTAGCTCAGCAAACTTCACGACGCGAGCAAATCCGGCGATTTCGCGCCACCCCTCGTACGCGGAGACGATTTTCTCCGCGTGCTGAGCCTCCAGCAGGTTCTGTGTGCGTCCGGCGGTGACCTCCCGATCCGCGTTGATGAAGAGCACGCCGTCGCGTCGACCCTCAGGCGCGCCATCACGGCCACGCAGGACAAGGATGCATGCCGGAATCCCAGTCCCGTAGAAAACATTGGGGCCGATGCTGATGACGGCTTCCAGCCGGCCTTCCTCGACGATCTGTCGGCGGATCTTCTGCTCTTCACCGCCCCGGAACAACACCCCGTGCGGCATGACGGAGGCCGCGATGCCGTCCGCCTCCAGCACTGCCAGCACGTGCTGGATGAACATGAGGTCAGCCTTCTTGCCCGACTCAGGCGTCCAGCCGTACCCCATCCGCTCGGCGAACTTCATGCCCGTCCGCCGGTAGTTCTGCGCGAACGGCGGATTGGTAAGAATGCGGTCGAAGCGCTGGAGCTGCCCGCCCTGCACATGCTGTGGATCGGTGAGGGTGTCGCCGTGGTGGATGACGCCATCGGCTACGCCATGCATAAGCAGATTCATCCGGGCCATCGCCCAGGCGCTGCCGTTATCTTCCTGTCCGTACACCGACAGGTGAGACTCGTCGCCGTCGTGATCCTGCACATACTCCTTGGCGAGGATCAGCATGCCGGCCGAACCGCAGCACGGGTCGTAGACGGACATGCCTGACTGTGGCTTGACCAATTGGTTCATCATGCGAATGACCGAGCGCGGGGTGTAGAACTGGCCGCCCTTCTTACCACCCTCGTCGGCGAACTCGCCGATCAGGTACTCGTAGGCGTAGCCCAGGAGATCGGGGAACTCGAAGTCTTCGTTGCTGAGCCGGTACTCGCTGAAGTGGTCGATGAGCTGCTGGATGACTGGCTTGGTCAGCTTGGTGTTGCCACCGCGGGACTCGGTGAAGCTGATGTACGAGAGCACCCCGTCGAGCGCCTGGTGGTTGTGATTCTCCAGCTGAGCAAGCGCCACGTTCAGGGCCTCGGCCGGCTCAGTCCGAGACTTGCCGACGATCGTGGACCAGCGGGACTCCTCCGGGACGTAGAACTCATGCGCCTTGTAGGCGCCTCGAGCCTCGGAGATCCGTTCCGCCTGCTCCTCGCTTTTCCCTTCCGCAACCAGCTTCTTAACCAGTGCCGCCTGTGCCACATCGAACTGGTCGGAGGCGCGCTTCAGGAACAGCATCCCGAAGATGTAGTCCTGGTACTGCGCCGCGTCCATCTTGCCGCGCAAGATATCTGCGGCGGCGTACAGATGCCGCTCCAGCTGCGGCAACGTGAGCTGTGCCACTCTCGTTTCTCCTCTTACTGCACGTCCCACAAGACATGCGTCCCGTGACAACCAGCCCACCCTAGGGCCTGGCTGTGACATCCGGCTTACGAAGCGAGCTTCGGGCCCCTCCTACATGCAGCGCACCGGTCGGCAGTGAGACAGGCGCACCCAAGACTCGGCTTCTTGTGAAGTGCCTCGCTTGTGGGAACCCCCCAACCGCCACGCCGTCGGTGACTCAAAGCGCACCGTCATCCAGCCCTACCTTCACCGACTCGATGGCCCGCTTCCCGCACGCTCGCCCGCCCACCGTCCAGCACACCCACTGCACGCGTGTCCACCGATTGTCCACCGGCGACCTCAGCCACGGTTCTCGTACTGAGCCGCCACTGCAGCACAAGGCAAAGGGAAAGAAAAAACCCCAGGTCACGGCGAGTGAGTCCTGGGGTAATTCCGAGCCGCCTTCGGGATTCGAACCCGAGACCTACGCATTACGAGGGCCTGCAAGATCGTGACGGGCCGTACCGGATGATCGCGCTAAATCCTGTTCTTCCTGATCAGAGGCTCCTCGCTGGCTCGCGTCTGCCGCGTCGTCCAGCAAGGTGCTGGCCCGTCCGCTCACGCATCGCTCACGCACTCGGAGGACAACGTTAGTTGATGGAGACCAGTTTCCTACCGGACCCTAACGCTAAGGGTGTGCAGGCAGTAGCTCGTAGCTACCGATGGCGTCCGCATAGGGCAGAAGGCGCGACTCCAGCTCCCGATGAAGCAGCTCAGCATCCTGCGCCGACAGCGCAAGCGTCGTCCGTCTGAGTTGCACAGCCCAGGCCCGCTTGTTGGGGAATGCATCGAGCGCGTGCACCAAGTCTCGGATGCTCAGTCCTTCGAGGAAGGGGGCGAGCCCCTGAATCTGAATCCCACATCCCGTGGTGAACTCCCGGTCTCCGAATCTGACTGGTGCCGTCAAGACGCTCACGGGCGCCGCCACCGAACCACGCCCAATGATACGGCCAACGTCACGGGTCGGGTTGCGAAAGCAGCCACGTGTGGTGTATAGCAGGACTTCGTCACCCACCCGCAGGACGCCACTCTGTCGTGCCCGCCCCGCCGGGAAAGCCAGACGCTGCTCGGTCAAAACCCAGCGCAAGGCGGAGCGCTCGCCGAGGATTACGAGGTGCGTGGAGGCCATACAGGTCACTTTAGCGGTGCCTCAACCATCCGGCGGAGCCCCCGTCCGCGCTGACACCACCCGCCGCGCCGGCACGCTTCGTTGCCAAGCTCCACGGAGCAGGGTGATCACGCCGGCCCGACTCCCTGCGCCTTCTACGTCCGTAAACTGGCACAACGGCACTGCGCATCAAGCCTCCCCCCGACTCCTACCCGAAGGTACGTTTAAGTGATCAACGCTGACAAGCCGCACCGCTGGAACGATGATGTCCAGGCTTCCGTGCGCCTGTACAACCAGTGGTTTCTAGATGCTGCTCCAAAGGCTTACCGGGATACTCGGCAACTCACGATCGACGAGGTGGAACAGGCTTTCCAGCGGACGGCCAATATGACGTCGATCACACCTGAGGTACTAAAAGCCCACCCTAAGACCTTGGCGACTCTCCGCATGAGCACAGCGCCTCCCATTGCTAAGGGCTGTCCCGTAACTGCTGGTCACAGATGAGATGATCTTGGCGTGGCTGGTGTGATCACTGCGTCGGAGCCGTCCTGGATTGCCCCGTTCAGCGGGCTGAGCCCGAGGCAGTTCGGGAAGCTGGTGACGGTGCTGCGTCGCGAGGGTGCGGACGCGGTCCGCAAGGGCCGGCCGTGGAGCCTGCCCCTGGAGGACCGGGCACTGCTGGTCGCGGCGTACTGGCGCACAAACCTGACCATGCGGCAGCTCGCCCCGCTGTTCGGGGTGTCGAAGTCGGCGGCGGACCGGATCATCGACCACCTCGGACCGATGCTCGCGCTCCAGCCCCGCAAGCGATTCGCCAAGGACACCGTGCTCATCGTGGACGGCACACTGGTCCCCACCCGGGATCACACCATCGCCGAGCGGTCGAAGAACTACCGGTACTCCACCAACCACCAGGTCGTCATCGATGCCGACACCCGCCTGGTCGTGGTGGTCGGACGGCCGCTCGCCGGCAACCGCAACGACTGCAAGGCATGGGAGGAATCCGGCGCAAAGGCCGCCGTCGGCAAGACCCTCACGATCGCCGACGGCGGCTACCCGGGCACCGGACTCGTCATCCCGCACCGCCGAGAGCGCGGACAGGCCGGACTCCCGGACTGGAAAGAGGAACACAACAAGTCCCACAAGCAGGTCCGAGCCCGCGTCGAGCACGTCTTCGCCCGCATGAAGACCTGGAAGATCCTCCGCGACTGCCGCCTGAAGGGCGACGGCGTCCATCACGCCATGCTTGGCATCGCCCGCATGCACAACCTCGCCCTCACCGGATAAACCGGCGGTCCGCACAACGGCCTCCCCCATACCCGAGGCGACCCGAAGATCATTTGCGGGACAACCCTTAGGGACCGTCTGGTCGGCCTTTCGCACGGCAGCAAGTCACTGCTTGACACGATGGAGAAGGGAAAGCTCCCACCCAGGATGAAGGGGGACGTGCTCGACACGCATCTCGCGAAGATGTGCGCCGTCCTCACGGATCTTCTGGACTTGGACCTGTTCCACTGGTACCCCACGGGAGAACCAGCAGAGCCGCGCCAGCGTGAACTGGCAGCAACCGTCGTTGCGGATCGCCTCTGCGGCGCCATAGCTGATCCCATCGTCAGGAACGCCCAGGAGCGCAGGCAGCTAGCCTTGATTGAAGAGTGGCTTCTTGCGCGCGGATACACGAAAAAAACACACTCGGCTTCACTTCCACTGAACACCATGCAGCCAGGTACCTTTTCGTTTCGGCAGAACGTGGTGGTTGGGAGCGACCTCCCAGTAAATATTCCCGTTGATGCCGTCATCCAGCCACACACCCCGCACAGCCACAAGCTCCCTATCCTAATAGAGGCCAAGTCGGCGGGCGACTTCACTAACACCAATAAGCGCCGCAAAGAGGAAGCCACCAAAATACACCAGCTTCAGCTTAAATATGGTAACGAAATTTCACTGACCCTCTTCCTCTGTGGATATTTCAACACCGGATACCTTGGGTATTCGGCAGCAGAGGGCCTGGATTGGGTATGGGAGCATCGAATTGACGACCTGGAGGCCGCTGGTGCATAGCGAGGCGAGAGAGGCCGAAGCACGCAGGCTACTGCTACAGGAAACCTTGGATGCAGAACGCACTTTCCTAGAGCGAAATCAGTGGGGCCAGTTCGCCACACCACCCTCCCTGGCAGGGGAGATCATGCGCTACACCATTGACCTGCATGAAGAAACGCGCATCAATTTCCTTGAGCCTTCTTGCGGATCTGGCTCGTTCTTCTCGGCCCTGCTGCGAAATTTGGGCGACAAGAAAATTGAGCACGCAGTCGGTGTCGAGCTAGATCCTCGCTTCTCCAAGGCCGCCTCTGATCTCTGGACGGGGCAGGGTCTGCGTGTGATCGAAGGTGATTTCACGTCACCAAGTCTGGTCAGTGGCCCGGTCGCATCGTTGCTGGTCGCGAATCCGCCATACGTTCGACACCACCACCTGGGTATCGATCAAAAGCGTGATTTGGTCGCTCGCTGTGCAGACCAACTGGGAATCAAGCCTTCCGGACTATCCGGCCTGTATCTGTATTTCGTCCTTCTGAGCCACCGCCTGCTCCGCGCCGATGCAGTGTCTACGTGGCTCATCCCAAGCGAGTTCATGGACGTCAACTACGGAACTGCTCTGAAAGAATATCTAGCAACTCGAGTACAACTCGTTCGAATCCACCAGTACGACGCCGCGGAGGTACAATTCGACGACGCCCTGGTAACGTCAAGCGTCGTCGTATTTAGGAACAGCCCGCCCCGCCCAGGGCACACAGCGGAGTTCTCTTTCGGTGGGACACTTTCTGAACCCAAGGTCACCCATCAAATCCCGAGTGCGGCATTGACCCCGGAGGCTAAATGGTCCCGATATGTCACCGGCGTCATGCCAGCAGACATTAACCTCAAGCAGACCGGACCCAAGCTTTCCGATTTTTTTAAGATCCGCCGAGGGCTAGCTACTGGCTCCAACGCCTTCTTCATCATCCCTCGTAGCGAGGCAGAAAGGCTCGGAATTAAGCGTAACTTCCTGCGGCCGATCCTCCCCAGTCCGAGAAAACTCAAGGGCGACGCGATTACAGCGGATGCCTCTGGGTGGCCAGACATTCCCGAACAGCTCGCCTTGCTCGACTGTCCACTTCCAATCGAGGATCTCCTCCTAGAGAACCCTGCATTGGCCGCCTATCTGAGCACTGCAGATGAAAAGATCCGTGGCGGCTATCTCGTAAGCAAACGGTCCCCTTGGTATAAGCAGGAGCAGCGAGAACCCGCTCCCATCCTACTGACCTACATGGGTAGAGGTAAGGACGATCAACATCCCCTCCGGTTTATCCGCAACGACTCCGACGCGGTGGCCACTAACATGTACTTGATGCTCTACCCAACAGCTCTATTGCAACGTTACTTGGCAGGAGACCCGGAGCGAATCAAGCAGGTACATAAAGCCCTCCTAGCCATCACCGCCGCAGATCTGCGCGGCGGAGGCAGGGTGTATGGCGGTGGGCTGCATAAGATGGAGCCCAAGGAACTTGCGGCACTACCAGCCGACGGCATCGCTACCCTCGACCCCGTGCTCCGCGAGGACATCTCGATGGTGTCGGTCCCTCCGCGTAAAAGGACTGGCCGCCCGCAGATGCCCGGGCCGTCTGCCAGCGAAGTTCGGGCCTGGGCACGCGCAAACGGTGTGTGCGTACCCGATCGCGGTCGGCTTCGCCCAGAAGTGTGGGATGCCTGGCGACAGGCACATGCAGGCGAAGCATCTCCCCTGAATATCGATGCAGGGGATCAAGTCGCTTTGTGGTGAAAGCAGGAACCTTCGGATACTAGCCGTTTCGAAGCCTACGCATCCGCGTTACGCTTTCGGGGGACTCGCACCAGCCTGAACCAGTTGGTCCTGCCAACCTAGCCATTCGTGTTCCGCAGTCACAGCTCGTGTAGGGCGGCGAGGACCTGCCCCATCAGCAGCGGCGTGATTCCGGGACCGCCGCCGGCGGGGCCGGTGATCTCTTCGTTGGGTTGCGTTGGCACTTCGGCCCAGACGGTCTTTCCTGGCGGGGAGGGCTCTGGGTAGTAGCCCCAGCAGTTGGGTCTGCTGCACCTTCAGGTGACAGGTTCAGTCACGCGGCCTGAAGGGCCGGTGTGGTCATGACGGTCTCGTATTCGACGGGTGTGAGTCGGCCCAGTCCTATTTGTCTGCGGCGTCGGTGGTAGGTCCGTTCGATCCAGGTCACGATCGCGATTCGGAGTTCTTCGCGAGTGGCCCAGGTGCGGCGATCGAGGATGTTCTTCTGCAGCAGGCTGAAGAAGGACTCCATGGCCGCGTTGTCACCGGCTGCTCCGACTCTCCCTATCGAGCCGGCCATCCGGTGGCGGCCGAGGGCTTCGACGAGTTTCCTTGATCGAAATTGCGATCCTCTGTCGCTGTGCAGGATGCATCCGGTGACGTCCTGGCGCCGGGCGACAGCGTTTTCCAGGGCGGTCACGGCCAGGCGGGACTTCATCCGGGCGTCGATGGAGTAGCCCACGATCCCGTTGCTGAAGACGTCCTTGACCGCGCAGAGATACAGCTTGCCCTCGCCGGTGGGATATTCGGAGATGTCGGTGAGCCACAGGCGGTTCGGACCGGTCGCGGTGAAGGTGCGGTTCACGAGGTCGTCGTGGACCGGCGGGCCCGCCTTCTTTGTTCGGCCACGCTTCTTGCCGAACACGCTCCACCACTGGTTGCCCCGGCAGATCCGCCACGCGGTCCGGTCCGCCATCACCGCTCCGGTGCTGCGGGGCCTCGTCGGCCAGGAAGCGGTAGCCGAACTCAGGGTCGTCACGATGGGCGGCGAACAACGCGTTCGCGCGATACGCCTCCTCGAACTCGGCGCCGGTCACCGGGGCGCCGAGCCAGCGGTAGTAGGGCTGTCTGGCGAGCTTCAGCACCCGGCACGCAACCGTGACGGGCACCCCGCCTGCGGCCAGCTCTTTCACGAGCGGGTAGATCCTTTTCCCGGCAGGTTCGCCTGCGACAGATACGCCGCCGCCCGCCGCAGAAACCTCGTTCTCCTGCTCCAGCAACTTGATCCGCCGACGTGCTTCCCGCAGTTCCACGCTCTCCTGGCCGGTCGTCCCGGGCTTCACGCCGTCGTCGATGTCCGCGCGGCGCATCCACTTCCACAACGTCATCGCGTGGACGCCGAAGTCGGCGGCCACCTGCTCGACCGTGACGCCCGGGCCGCGGTTCCTCGCGACCCGCACAACGTCCTCGCGGAACTCCTGGGGATAAGGCTTGGGCACAGCGACATCCTTCCCACCTGCCATACAAGGCAAGCCAGTTCAGATGACACCCGTTCGTGCGGCAGACCCTCGTCCCAGGTCTGGCTAAGGGCTTGCAGGGAATCAAGGTGTTACTTCCCTGTAATCCCTTAGCGTGAGTTCTTACCTCAGTGATTTGAGAACCGCGTCAATGAGCGACACCGCACGGACATCGTCTGGGCCGCTGATGATGTGATTCATGGCGTAGCCGAAGGCGATGCCGTGCTCTGGGTCGGCGAAGCCGAGGGAGCCACCTCGGCCATTGTGGCCGAAGGCACTCGGCCCCATCATTGGGTTGTCCTCGGTGGGCAGTTGGTATCCGGAGCTGAACCGGCTTGGCGCCACCAGCACCTGATCCATTCCGGCTGCCTGCTCCTTGATCGCCAGAGTGAGGGCCTCGGGGGTGAGCAGACGGGTGCCGTCCACCTCGCCGATCAAGGCCGCGTACATACGGGCCAGCCCGCGCGCGGTGCCGATTCCGTTGGAAGCCGGGAGTTCCGCGGCCTGCACCTCGGGTGAGTTGAAGTCGATCGCGGCAGGGTCGGTCACCATGTACGCCCTGTTGCTGAACGAGTCCGGGTCGCTCCAGGCGGCGACCTGATCACGGAGTTCCTCGGGGACAAGCTCCGGAGCCACAGTCGTGAGGTCCACGGCAGGCTTGCTATGCACCATGTGGCTGACCCGTTCGCGTTCATGCGCCGGCAGCCCGATGAAGAAGTCGAAGTCCAGCGGGGTAGCGATCTCGTCAGCGAAGAAGCGGCCCGGCGTGCGGCCGGAGACTCGGCGGATCACCTCACCGACAAGCCAGCCCCAGGTGCGGCCGTGATACCCGTGAGCGGTACCCGGAGTCCACGCAGGTTGTTGCGCTGCCAGAGCCGCCGCCATCGGGCGCCAGGCCAACGCGTCATTCAACGGCACCGGTTGATCCAGTGCGACTAGGCCAGCCTGGTGGGACAGAACCCAGCGCACCGGGATGTCTGCCTTGCCGTTCGCGGCGAACTCCGGCCAGTACGTGGCGACGGGCGCGTCCAGGTCCAGCTCGCCGCGCTGGGCCAGCAGGTGTGCGGCGGTCGCTGTCGCTCCCTTGGTCGCCGAGTAGACGAGTTGCAGGGTGTCGCGCGTCCATGGTCGGCCGGTGCGGGGGTCAGCGATGCCACCCCACAAATCCACTATCGGGTGGCCATCCCGGTACACGCACACCGCCGCCCCGATGTCTCCGTTCCTGGCGAAGTTCTCCGCGAACGCCTCACGCACCGGTTCGAAACCGGCCGCGACCTCACCGCCGATCACCGTCATGTGTCCATCGTGACACTCCCGACGCCTGCTTCCGTGGGCGGCCTGGCTCTCGGCGTACGGGGCCTTACCAGCGTCAGGTAGTCACGGGCAGTGCCTTGAGACGCTCGCGGAACTCGCGAACGGCTGGGACAGACGTGTTCGGTTCAAGCCGTGCGGAGAACTCGTTCAGGCGGCCCAGCGCTCGCATGGAGCTGACCTTGTCTTCCAGGAGTTCCGCTCCGCGGTTCGCCGCTTCGAGCGCTCCCTCCAGGTCGTTGCCAGCGAGCCGGGCTTCGGCCAGGCGCGCAGTCCGTACAGTCATGTCGCGGGGTGCTGCCCTGTTGACGGACGTCTCCAATGCACTCGTCGCACGTTCCACCTGGCCCGCGCGCAGCAAGACCTTGCCCTCGGTTGACTTGAGCTGAGCCTCGCCGAACCAGTCAAGCCAGTCGGGGTCTTCTCCTTCTGTGTGACGCCCCCAGTGAGACGTAGCGCGGTTCAGCGCTACGCCGGCCCTCTGGTGGTCGCCATCGCGGGACAGCGCTTCGGCCTTGTGCAGGTAGAGGAAGGACTGGGTGTAGGGCGACAACGTTCGCGGTGCGTTGTCGATGGCGGTGGAGATGAGGTCGACCCGCTCGGCAGTCTGGCCGGCCTCTGAGACCTGGACCCCCATCTCGGCCAGGACGAAGGCGCCGAAGGCGTCGTCCCCAGCGGTGCGGGCGCTGCGCAGGGCTCCGATGTAATACCGCTGTCCTGCGGAGCGCAGCCCAGCGTCATAGGCCATCCAGCCGGTCAGATGTGACACGCGGGCGGCCAGTGCGTAAAGGCGGAGGCGGATCGCGTCCGTGTACCGTCCTGCGTCAAGGAGACCCGTGATCAGGGCGAGGTCGCCCCTCGCTTGCTCCAGGAGCCGAGCTCCGCCGAGTTCGTCGTCGAGCGCGCGGAGGGTGCTGATGCGCTGCTCGATCGTCGAGACCATCGTGTTGGTGACGCGATCTCCGTTGAGTGCCGAGGCGAAGGCGGAGGGTGCCTCGGCCCAACTCGCCGCCAGTCCTGTCAGGGCGACGCCGGTGATCGTGAGAAAGCCTCGGCGGTCCAAGCATCCACTCCCCACCAGATCTGTCAGTGCCTCGACGGTCCCGGCCTCGTTCCAGGGAGTGCTGAGCCCGGTCACTTCCCATACCGGAAGCCAGTATGGCCAAGCCGTAGCCTGCGCCCTTTCGTGCGGCACACGCAACAGGTCGGCGATGACGTGTCGCGCATCGGCGTCCGGCTCCTGGCCCTGCTCCCATTTCCACACGGTGGTGCGGTTGGTCGCGAGCGGGACGCCGAGCGACTTCCCCTGAGCCTGCATGAGTCGCGCGAACTCGGCCTTCCCCCAACCGCGCGACTGACGGACGTAAGCCAGTGGGTGGACTGCTAAGGGCTCACCAGGCACATCAGCTCTCCCGTCATCCCCTTGCGGCGTCGCTCGGAGGCTACTCGCCACGCACGTGCGTGGAAGGGCGTCCCCAAGAGAAACCCCCTAGAAACGTTCCCGGCTTGTCCGCTCCGGCCGTTGACTGAGATCAGCCGCCCAGGAGCAGCGCGTCGGCGCCCGTTCCGGACGGTCACCTCAGATCGGCGGCTCCATCTCTGTGTCCCCCATCGGGGATGGAGCCGCTCTCCAGCTCTTCGGAGGCGTCCGCCATGCCCACGCTCGTGTCTCACTTGGCCCTCATGGGCACGAAGGAAGAGGTATCGTCCGCTCGCCGCAGGATCGTTGCCAAGGTGCGTGAATGGGGCGTCCCTCTGGATGACGAGACAGCCGACGCGATTCGTCTCGTCGCGTCCGAGCTCATCACCAACGCCGTGGTCCATGGCAGCGGGCCTATCACAGTCACCTTGTCCCACAGTTCGGGCAGCTTGGTGATCGACGTGCTGGACACCAACTCCAAGGTTCCGAAGTCGGGTTGCTTGGAAGCGGAGGACGAGGGTGGTCGTGGTCTGGTACTGGTGGATTTCCTCGCGGCTCGGTCGGGTTGGAAGCGCGTCCAAGGCGGGAAGCACGTGTGGGCCGAGATCGCTCTTCCGAAGTCGGGTCCTGCCGATGAAGCTGCCGTCCAGGGCCAGTTCTCTGGGGCTCGATCACCGAGTTCTCGCGGCCGAACCGTGCCGTCGTCGCTCGCTTCGGCTATCGCCTGATGGGGCGGCATACGTGACGCCTGGCGACGATGACTGAACCCGATGTCGTATTCAGGCCGACGCGTCGGGATATCGACCCAGCCACAGGTGAGCTCACTGCGTACGCGCTCTGGGACCGCCACAGCTGGGAGCCGAGCGGCGAGTGCTGGCTCTGGTGCGGACGGCACGGCGTCGAGGTGACGTGGATCGGGCCTGTCCTCTCCAGCGGCATGCACGCGGCCCTCTACTCCTGCCGCGCCTGCCTGTACGAGCTGGACCAGCGCGTCCTGCAAGCCAACATGCGCCAGGACCTTGCTCTCCCCCAGGTTGACGGACCGAGACCTTCGCGCTGAGAGCACCCCTCACGATTCCGCGGTCCGCGCATCTCCGTTCCCCTGCGGCCGTGGGGACGGCTTGCAGTACGCACGTTTGCCATCGCGCAGGCACCGACAGAGCCTGCGCCATCCAAAAGGGCTTCCCGCCGGAACCCCGGCGGGAGAACCGAAGAGGAAGGAGCACGAGGTGGCACAGAGTACGACGACAACGCCGCCGGCCCCGAGTGGCCTCCTGGTGGCGGTGGAGGAACTGACCGCCGTCCACGACCGGTACGACAGCCTCCGGTCCGACAACCAGGGAAGCTCGGGCGACTCGCCGTGGCCGGGCGGTGACGGCAACTTGACCGACACCGAGTAGCACCCAGGCGGCGGGGGCGACAGGGCCTTTCGTGTCGCCCCCGCCGCGTCCACGTTCATGTAACCGCACTCAAGGAGGCAGTGATGGAACACCAACTGGTCAGCGCCGTCGAAAGGGCGCTGGGATGGAGTGGCCCGGAAGAGATCGGCAAGGGCTTCGCGCGCGGGAACATAGGCGACCCTGACCTCGTCTCCCGCATCCTCACCCCGAACCGCCTGCTCGACATCGCCATGCGCAGGAGCCTCAGCCGCCCGCAGTTCCGGTGCTTCCAGAAAGGCGACGAAGTCCACCCGGCCGTCTACTACACCGACAGCGTCAGCCCCCGCGGCCAGAGCATCCCCATGGTCAACATGCGCAGTCTGGGCCGGCTGCTGGACGAAGGTGCGACGCTCATCCTCGACCAGGCCAACGTCTTCGACCCGACGATGGAGGTCGCCTGCCGGGCGTTGCAGTGGTGGTCACACGAGCGGGTTCAGGTCAACGCCTACCTGACGACGAACGATGCGGCGGGCTTCCCTCTGCACTGGGACGATCACGACGTGGTGATCGTCCAGCTCGCGGGCGAGAAGGAGTGGGAGGTGCGAGGCACCTCTCGCCCGGCGCCGATGTACCGGGACGCCGATCCCAACAGCACGCCGACCGACGAGATCGTCTGGTCCGGCGTGATGAGGACCGGCGACGTCATGCACATCCCGCGGGGCCACTGGCATCAGGCGACCCGGACCGGTAGCGGCTCGGGAAAGAGCCTCCACGTGACGTTCGGCGTCACCAAGCGCACCGGAGCGAGCTGGCTGGCGTGGCTGGGTGACTGGTGCCGCGAGCAGGAGATCTTCCGGCACGACCTGGACCGCCGAGACCCGGTCGGCGGCCAAGCCCTGCTCGAAGCCGCCACCCGACTGATCGGCGAGCGCTCCCCGGCCGACTACCTGGCCGCGTACGAGCAGGCGACGACGCTCCCCCGACACGTCCCGTACCTCGACATCCTGGCCCCGCTCGACACCGTGGTGTGCACCACCCACTTCCCACCCCAGATCCACGAGAGCGGGGAGACCGTCACTGTCGTGGTTTCGGGCAAGCGGCTCACCCTCGCGGCCAAGGCCGTGCCCGCGCTGCGGATGCTGCTCAGCGGCCAACCCGTCTCCCTGGAGCGCGCGGCGGCCCTCGTCGGGGCCGACGTGGCGGAAGTGGCGGAGATCCTGGTGAAGGAGGAACTGTGCGCGACACTGACCCCCGAGTTGTCCTCGGGCTACACCGGTCTCGTCATGGACGTCGCCTCTTGATCGGCGCGTTGGACCTCGGCGTAACCGCGCTCGACACCAGCACCAACTACCTCCGCTTCCGTTCGCACGAGGTTCTGGCACGGGTTGCCGACGACCTGCTGCCGAAGTTCCACCTCTCCACCAAGGTGGGCTACTTCCCGGGCATCAGCGGGGCCGAACACTCCCTCGCACCCGAACGACTGCACAGCGCGGTGGAGGAAGCGGCCCGTGACCTCGGGCGGGAGCCGGACCTGGTGTTCCTGCACAACCCGGAACACTCGCTCACGCCGGGCACTGACCGGTCGCGCGAGGCCCTGGCCGAGGCGTGCACAGCCCTCGCCAGTGCGACATCACGCGGGCTGTGTGGCGCGTGGGGCATCGCGACCTGGAACCCTACGCCGCTGCCACCTCTGGTCGACGCATCCGCGCCGACCCCCTCCACGCTCATGGTGCGGGCCGGCCTGCTGGTGGGCGCCGGAACACTCGATGCCGCCGAGGCCCTGATGGAAGCGTGGGGCCTGGGCACGGGCGCGATGTGGGGGATGAGTCCTTTCGGCGGCAGCACCAAGGCACCGGTGTGGGCTCGGGCAGACGCCCGCGTCTTCCTCCGCAACGGCAGCGGGTACTCCCGTGCACAAGCGGCCTTCCGGATGGCCTACCAGCTGCCGAACGTCAGCGCCGTAGCCGTCGGGACGGACGAACCCGCGCACCTCGGAGAACTCGTCGGCGCCCTGGCCGCCACCCCCGACGAACACGCAGTCGCCGAGTACCGCACGCTGCTCCGTGACCGCCCGCGCACTCAGTCCGTCTGAAGGTCTTGGACGATCTGTTCCGCCATGTGGCGCGCAGGCTCCAGCCGGGGGTCCTGCGGATGAGCATCCGGGCCAAGGATCTTCGAACACACGAAGAGCGTCATCAGCTTGCCGTCCCGGCTCGCGAAGTCTGCGCGCCGCTCCCGCAGCACGCGGTCCGCCAAAGCCGGGACGGCGAGCGAACTAGCCCACAGCGATGCGGAATCCAACCCACGCGGCGCGTTACCCCAGTCCTCCCAGTCGAAGAGAGAGAACGTCGGCGCGCTCATGTTGGCCCAGTTCAGGTCCGCATGGGCCGGCACCCACTGCTCAACGGTGGTGTCGAGGGAGTTGGGAAACGCGGCGCGGATGGTCCCGGTGACGAGGGCCTGCGTGATCGTCTCGGTATCCGGTGAGGCCACGCGGCTCGTCCGCTGTGCGGCGAGGGCGTCCAGCGAGGAGCTGAACGCACGCCACCATTCGTCCGGGAGTTTGGGGTCTTCGCTCAGCACGGCGGTACCGATGGGGTCTCCGGGCAGGAGCTCTGTCTCGTCAGCCCGCCACATGACGGGCTCGTCTGCGTCCCGCCACACTACGCACGCCTGCCATTCGGGCTGGGCGACGCCCTCGAGACGAGCGGCGCACTCAGTGCCGTTCCACCCCTGATCGCCAATCTTGTCCACGAGGCGCCGCTCGATCCGGACCCAGGTGTCACGATCAGTTCGTGCACCCACGGAACGACGCTTGCGGACCACCGTGTCCCGGTCGAGACGTGTCTGGAGTGATCGCTCGACCTGATCAAGAATCGTGTCGACCGGCTGCACTCGCAGATCGACAGCCTGACCGGTGGAAGTCGAGAGCGTCATAGGGCGACGGTAGCAGCGTGGAATACGCCGTGATGGTCCCTTTCGCACCGCCTCTCGTAGTCGCAGTCCATCACCTTGAGCGGCGTGCCGGACTGCGCGGCACACCGCTGTCGGCGCCAGCCTGTCACCGCCCGAGTCGGCGATGCTGTCCTGGTTCGGCCACGGGATTGGTCGACTGCGTGAGCGATGTGCCGGCGCCCATTGCCGGTGTCCAGGTGGTCGTCTTCCGCCGTGCCGCTTCGGCTCGGCGGTTGGGGGCGGGGTTACGGCTGGTGTGCTGGATGCGGGTGATCAGGACGCGGGCGGGTTGGCGAGCGGTGGTGAGTTCGCGCTGAGCGGCGGCTTCCTTGAGGAGCTGGTGGAGTTTGTGGCCGCTGGCTTCGGCGTCGGCGAGGACGGTGGCGAGGGCCGGCCAGGCGGGGTCGGTGAGGATGCGGTCGGCGTGATCGGGGACGGCGGCCCGGACGTCATGGGCCAGAGTTCGACGGGCCTGCTGGCTCGGCTGACGAGCGGCGAGGGTGTCGATGACCGGGGCGAGGGCGTGGTCGGCGGCGGTGTGTAGGTGGTGGAGGGTCTGGCGGGCGGCTTCGGCCTGGTGGGCGTGATGCTTTGCCTCGTGCCAGCGGGCGGCGATGATCGTGGCCCACACGAGGGCGGCGAGCAGGGCTGCGAAGGCGCTGCCGTCGGGGCCGGTGGTGGTGTGGGCGATGTCGCGGGCTGCACGGCGCAGGGTGTGGGCGGCCTGGTGCTCGGCTCGGATCTGGGAGCGCTGGGCGCGGGCGAATGTCTGTGCTGCGGTTCGTAGTTCGGCTCGGGAGTGGCCAGGGGCTTTCTGGGCGGTGGCCTCGATGAGTTCGCCGAGCGCTGTGATGTGGGCCTGGGCGTGGGTGTCGTCGGTCATGCCCTGGTGGAGGGCGTCGGTGGCCTGGTGCCAGGGGGTGGCGGGGCGCTGTCGGCGTGCGGTGGGGTGTTCCTCTGGCGCGGTGGATTCCAAGCGGGCTTTGAGCTTGGGGAGGGTGAGGTCGGGGGCGATCCTTCCGCCGGGGTGGAAAATCTGCTTCCCGTCCTTGTTGAGGTCGCCGGGTCGGCCGGCGGCGTAGCCGAGGAGGTCTCCGGACGGTCCGCGGCGGGGCTTGATCGCGATGCCGTCGGCTTCGAGGTAGGCGAGGAGTTCCTCGGCGTTGCCGGCGTGGGGGATGGCGGCGCGGATGCGGTCCTGGAGCCATTCGCGGCTGGTCTGGTCCCAGCCGAGGCGTTGGGCCTTGTGCATCTCTGCCTGGGTGGGGCGCTTTCCGGCGGTGCGGTCGCCCTCCTTCAGTTGGCGCAGGCCGTAGTCGGTCTCGATCTGGCGGCAGGCGTCGCCGACGCGGATGCCGCTGCCGTGGAGTTTGGGGCGGCGGCCGTCTTCGCGGACGGTGGTGGCGAGGATGTGGATGTGGTCGTCCGCGTGGCGCACGGCGATCCAGCGGCAGCCGAGGTCGTCGCCGGGCGGGGCGATGCCGGCGGCTTCGACGATGCGCTGGGCGATGTCGGCCCACTCGGCATCGGAGAGGTGCCGGTCCTCGGGGGCTGCGCGGACGGGGCAGTGCCAGACGTGGTCGGTGATCTTCTTCCCGAACTCGCTGTTCCGGAGATGCACCGGCTCGTCCAGGTGGTGGGCGAGCTGGGTGAGGGTGGCGTCCGGGTTTCGTCCGGGGTCGGGCATGCCGAGCATCGCGAAGCCCGTGACGATGTGCGGGTCGAGGTGCTCGTCGTGGCGGCCGGGGCCGTAGAGGTAGGCGAGCAGGCCACGGGTGTTGGACCCGGCCGGTTTGATGGCGGCGATCACGCGGCCTGCTCCTTCTCCGCCTCGGCGGGTTCACACAGGGCCCCGGCGAGCAGGTCCAGCAGGTGGTGCAGCTCATCGAGACGGTCACGTACGTCGGGCGGGGTGAGGTCGCTGTTGAGGGCGCGGGCGATCTGGTTGACGTTGACGCCGATCCGGTTGAGTTCGCGCAGTACCTGGGCGCGGAACATGTGGGTGCGGCGGCGGTCCTCGGACAGCGGCAGGTTCGCGGTGAACCGGCCGGTGATGAAGGCGAGGGCGATGTCCGCGGTGAAGCCGGATTCCCCTTTGTAGCCGTGCTCGGCTGCGGCCTCCTGGAGCGCGGCGTGCTCGTCGCCGGTGAAGCGCAGCGGTCCGACACGGACGGTCCGCTTGGTGCCGGTGAAGCGGCGGATCGTCGGCTGCACGCTCTGCGGTGCTCGTTCGCCGGCCGTCGGTTCGGTGGCGGGTGCGGGGCGAAGGATCTGCTGCTGGGCGGTGTGGAGCTCGTCCTGGTCGGGGCCGCCCTCGGCCCCGACCTCCCGGCCAAGCGCCCCTTGGCGCTGGGCCGACTCCGCCACCCCCGGGGCGGAGGTCCCCGAAGACCGGCCTTGAGTCGGACTCGGGGTACTACTGGCTCCGCCCGGGGCCGTCCGCCCAAATGCCCGACGCAGACGGGACAGCAGCGTAGGGGGCCGTGTCGAGGCGGACGGCTCAGCGGGCGTGTCGTCAGGTAGGTGCTGGCTGTGCTGCATGGAAGATGCTCCAAATGCGGCTCGGCGGACAGGATCACGGCGACCCGGTGGCGCGAGCCATCGCGTTGTCCACAGGTGTGGGGATCTGCGGGGCGACCGGCGGGTGCTCGGGTGACCGGAAGGGTTCCGGTCACCCGAGCACACGAGGGCGTCAGCCTCCGGAGACCTTGATGCCAGCGGCTTCGAGTTCCGGCCGGAGCGACTCCATGACTTCGGTCTGCCGCGCGCTTCCGATCGTCAAGTTCCGTTCCTTCACGGCAGCTCGCAGCAGGCCACGCGTGAGCTTGCCGTGCTGGCGACCGGCGGCCCGGCCGATGGCCTTCAGTTCCGCGATGGTCGCCTTCGGAGGACGGCCGCCGACTGGTTTGGCCTCCGGCACCGGGGGCGTGGATTCCGACCGCTCCTCGCCGGAAGCTTGCGGAACCTCGGCAGCAGCATCCTGCCGTCGACCCTCGCCGTGCTCACCGACCAGCCGGTTCCGCACAGCTACGGAGCCGATACTGGAGGGGGCATCGTTTGGTGCCACAAGCTGGTGGATCTGTCGCATCAGCACGCCGAACGCGACCATCGCGGCGGCCGGAGGGACGGCAGCGACCACGTAGTCGAGGAGCGGAACGCTGCGCTCGCTGTCCGCGCCGCTGACCCCAGCGACGTTCAGTGCAATAGAGCCGACCGATCCGGCAACGGTCACGGCGACCGCCCAGAGGTCGGTCGTACGCCGGAGCGCAGCCCGCAGCATGAGCAGTTCACCGGCGACGATGAACGCGTCCAGGGTGGCGGGCCAGGCCCATCGGCGGATGGGGGATGCGCCCAGCCCGTGCTGGCCTGCGACATCGGCGAGGTGCGCGTAGGACAGCCAGAACGCTCCGGCTGTCAGAACCACGATGACGATGCCGCCCGCGCGGAGCACGAGCCGCTCTGCGTCGGCACGCTTCGGGCGCTGCCCTTCGGCTGGGACGTCATCTCGTGTCTGCGGTGATGACGTGGTGAGGTGCGGGGCGGTCAAGCGGGAATCTCCTTGGGGTAGTGGGTGAGGGGCGTCTTTGCCGTCTTGTGCGTTGCACGTGCAGGTCAGCGCGGTACGGCAGCGCGCTGGACGTGCCGTCTTGGCAGAAGCTCTGGCGTCTTGTCCCGACTCGGGACAGGGGTGAGGCGGATCCGCCCCGGCTCCTGTCCGGGCGCCTGCATCCGCTGGGACGGCCGGTCGCGGCAGCCGTCCCAGCGAGCAGGACTGTGACCTGCTGCGATACGGCGAAGACGCCTGGGACGGGGCAAGACGGATCTGGACGCCGTGCCCCTGCTGGCTGCACGTGCTCAGGCGCGTGCGCTGCCGTCTTGCCCTCGGCTGCCGTCTTGCTGATGCGGGCCCTGACCTGCACGATCACGGCAGGGACGGCAAGTACGGCAACCAGGGAGGTGGGGGTCAGCTTTCGCCGCGACGAGCGTCGACCGGGTGGACGGTCGGGCAGTACCGCCGCCAGGCGTCCAGGAACTTGTTGCGCGTGTAGCCCTTGCGCTGAGTGCGGTCGGCCATGCGCACGTTGCCGGGCCGGATGTCGTAGTTGCGCAGCATCCCGCTGAGCTCCCGGGAGGTCAGGCCGTAGCGTCCACGCTCTCCCCACGGGGCTTCGGCGTCCGCGTTCAGGTGGTGCAGGAGGTCTTCGGTGGAGAGGCTGTCCGCCTCCCGCTGCGCGAAGAAGACCCGTCGGATGTCAGCGAGGATGCGCGCCCCACTCGGGTGGTCCTCCTCGGCCGCCACCTCGGCCGCGACCATCCGTGCGCACGCGATCCGCGCGAGCCGTGGCCAGCGGCCGCCGGCCAGGTCCGCAACGATCACAAGAGGCTCCCAGGTGTCGGCGGCTCGATCCTCGACCGGCATCTCCGGCTCCAGGCTCGCAGCGTCCTCCAGCAGCGGGAGGGCCCAGGCGCGGATACGGTCGCGCAGTTCGTGCAGGGCGGGGATGTCGCGTCGCGAGCGGAAGGGTTTGACCTTCTCGCCCTCGGCCCTGCGGCGCATGCGGATGACGACGGATCGATCCATGACGGTGTCCGGCAGGTCACCGATGCCCGCGATGGCCGCCATGGCGAAGGTGGCGAACTTGTGCGGGGTGTGGTCGTTGCCGACGACCCGGGTGACGTACCGGCCGCGCTGGTGGCCGGCGTTGAGGAGGCCGCGTGTCTCCTCGTTCTTCTCCGCGACCTTGGGGCCGAAGATGGTGTCGGCCTCGTCCACCAGCAGCGTCGGCGGCTCCTCCTCGTTGATCGAGCGGAAGATGGCCGCTGGTGTGGTGTTGATGGTGAGCATCGGTTCGTGGACCGTTTCTGTCAGCACGTCCAAGAGCCGGGACTTCCCGCACCGCTTCGCAGGTCCCACCACTGCCAGCCGTGGGGCGTGCTGCCACGCAGGCTGGAGCTGCGTCGCCACCACCCACAGGGTGACCGCGTTCAGAGCCTCGGACGAGGGAGGAATCACGAACTGGGCTATTTGGGAACGCAGTTCATCCAGCAGATCCGAGCCTGGCGTCGGTTCCGCGTCGGGAATGGTCTCCAGGCTCCTTGCCGGGTCCGCCTCGCTGCCGTCAGCCGGACCATCGTGCATCTCCGCTGTGGCATAGGCGGCCTGGGCCGGACCCAGATGAGCGCCGGGCTGGCCAGGGACGGCCGTGGCGGGCCAGGCCGCTCGGGCGGGGGAGGAATAGGGGTCGGGGGTTCTCGGGTTGCACTGGGCGGCTCCTCGTCTGGCGGCTGCGGGCTTGCACGCCCTTGCCGCCGGGTCGGATCTCACGGGATTGCTGGGGAGTCCTGGAGCCTCCGGCGTTGCACCGTCGGAGGCTCTCCCTCTTCTCGCGGGGGTCTCGGTACCGCGAGCGACCACGGACAGTACGTCCACGCCGTGCCACAGTCCAGCGTTTCTGTGTCAGCTCAGCGCAGAAGCGCCTACGGCGCATCAGGTGCCTCATGCGGCCAGCCCCAGCAAGGCCAACAGGTCTGCCGTCACCACCCGGTAGGCGTTCCCGAGCCTGAGCACCTTGCACGGGTACTGGCCGCGCTTGGCCAACTCGTAGCCCTTGCTCCGGCCGAGCCCCAGCGCGCGGTTACCCGTCTCCAGGTCAACGGCCGCCGGGAGCCCCAGAAGCTCCTCGCGACTCATCCCCTTCGCCCCTCCGGCGTCTTCGTTCTGACGCATGCGCACTCCATCCATGACTGAGCCCACGGCGAACGCGACCTCCGCGTCCATCTCCAGGTCTTGGAATCAACGCTAAGCGAGCTAATGTGTCTGCATGACACAACGCCGAAGTCACCATGGATCGAGCAAGGCCGACGACGAGGACGACGTCCCGGAGTGGGTGGACCAGGTCATGGCCACCGTGGCCGCCGAGGTCCGCAGACGACGGAAGGAACTGGGTTGGAGCGCACAGGACTTGGCCGACAGATGCGCGGAGATCGGCCATCCGATCCCCCGCAACGTCATCGCCAACATGGAGTCCGGACGCCGCTCCAACCTGCCCTTGGTCGACGTCATGGTGCTGGCCGAAGCCCTGAACACCCCACCCATCTGCCTCCTCTATCCCGTGGGCTACATCGAGGACGTGCAGCGGCTCCCGCTCCAGGACTCCACTTCCACTCTGGATGCGCTGCGCTGGTTCACGGGGGAGGAGACCGATCTCGGCGCGGACGACGACATGCTCCGCTACTTCCGAGCCCATCACGCCGCCCAGGAGCGGCTGCGAAGTGCGCGACGCGACGAGGAGTACGCGCGCTACCACGCCCAGACCGCCCCGAATGCCGACCGGAAGGCCGAGGCCCTCCGCTCCCAGGCCCGCGCCGCCGAGACGGCGGACGACGCCGAAGACCGCCTGCGCAGAGTTCGCGCCTTCATCGAGGAAGAGGGCGTCACGCCCCCGTTCCTGTGGCCCGACCTGGCCGACGTAATCGACTCATCCGGGAGCGATCCCGAAACCAGCGAGGAGAATGATCTTTGAAGGGCTCCACCTACCGCCGCTGCTCCTGCCGCGACGCGAAGACCGGCAAGGAACTCGGCACCTCCTGCCCCAAGCGCAACAGCAGGAACCACTGCACCTACTCCGTACGCCAGGAGCTCTCACCCCGCGAGGACGGCAGCCGCCGCTCCTTCTCCCGTGGCGGGTACGCGAGTCTCAAGGCAGCCCAGGCCGACCTCGACCACGTACGCGCCTTGCTCGGGCTCGCCGACTCGGACGACCCCGAGGGCACCGAACTCATCGCCGAGATGCTGGCCGAGGTCAGCCGCGAACGGTCACCTCTGCCCGAGGTCGAGGAGACGCGGCGGCGCCTCAACTCCGGTCAGGACCTCATAGGCAGCCTGACCGTCGCCGAATGGCTCGACCGGTGGTTGGCCGGCAAGCGCATACGCAAGTCCGGCCTCAACCGCTACGAGACCGATATCCGCGTCCATCTGAAGCCGCGCATCGGCAGCCGGCGCCTGGACCGGCTGCGCGTCAGCCACCTCAGCGAGATGTTCACCGACATTCGCGAGGCGAACGCCCAGATCCTGGAGGACAACGCCCAGCGGCGAGCCGCTCTCGACGAGCTGGCGACGGTGCCGTGGAAGGGCGTCGGGAACCGGGCTCGTCGCAAGGCCATGAAAGCCGCGATCGACGAGATGCCGCCCTTTCGGCGCGTCACCGGCCCTGCCACGCGGCTGCACGTAAAGGCCACCCTCCGGGCCGCCCTGAACGACGCGATCGGGCAGCAGATCATCACGTTCAACCCGGCCGCCCACGTCGAGATCGACCCCGTGCGCAAGCCGAAGGCGCTCGTGTGGACGGACGAGAGGGTCGCCAAGTGGGAGCAGACGGGCGAGAAGCCGTCTCCCGTGATGGTCTGGACTCCGGAACAGACCGGTGCCTTCCTCGACTTCGTCGCCGGGGACCGGCTGTACGCGATGTGGCACCTCATCGCCTTCCGCGGCCTGCGCCGAGGCGAGGCGTGCGGCCAGCCGTGGTCGGAGACGAACCTCGACACCCACTCCCTCACCGTCTCCTCTCAACTCGTCCAGGACGGCTGGGAGGTGGAGGCGTCCGACCCCAAGACCGACAGCGGCTCCCGCGTGGTCGCCCTCGACGACGACACGGTCGACGTCCTGAAGCACCACCGCGAACGGCAGGAAACGGCTCGCAAAGAATGGGGCACAGCCTGGGTCGAGACCGGCCACGTCTTCACCCAGGAAGACGGCTCCTGGCTCCACCCCGGCAAGGTGACCGACCTCTTCGAGCGCCTCGTCGCCGCCTCCGGTCTCCCGCCGATCCGCCTGCACGATCTGCGCCACGGCGCGGCCACCCTCATGCTCGCCGCCGACATCGACATCAAGATCGTGTCGGACACCCTTGGGCACAGCGACACCCGCATCACGCGGGACATCTACCAGAGCGTCCTCCCCCACGTCGGCAAGAGTGCCGCCGAGGCCACCGCGAAGCTCATCCCCCTCCAGCGCAAGGCCGAGGCCGAGAAGGCCGCGCGCAAGGCCGCGAAGAAGGAGAAGGCCAGGAAGGCTGCGGCCAAGGCGGCCGACGTCGGCAAGGGCAGCAAGGGCGGCGGCAAGCCGAAGAGGGACAAGGCGAAAGCCCAGGCCAAGGCAGCCAAGAAGGCCACACGCCGCAAGCCCACAAAGTAG

Protein sequences of DBSCAN-SWA_1

>NC_020990|3003079:3063916|3012919_3013879_+|WP_003949716.1|DBSCAN-SWA
MDDHPLHPIGELSRRTGTPVRTIRFYSDEGLLPPAGRSPSGHRLYDEAAAGRLALVRTLRELGIGLPAVRKILDRELTLPEVAAAHTKALDAQIAALRVRRAVLDTAARQGTGAEEIRALHQLAHLSRGERKSLVDAFLTAVFGPEPGLPLAGVARTLTPELPDEPDAAQLRAWLELAALTRDPGFRAHLRGLCQEAAPGTGTPGVPRPDLTATVREIVAPALATGLAPDSPRAEEILTVLLARCAPPPGGAEAERVRKLTARLERYTDPRRERYVRLLAVVNGWPPPSSTRPALTWATEALRARRGTEPVSPRAATGA
>NC_020990|3003079:3063916|3003079_3003658_+|WP_003949729.1|protease|DBSCAN-SWA
MLHSRWFKTAGAAAALTLATATAAYATPAPAPAPDLTAAAVTLRYDDSRAAGWEAAIAAGVANWNASVSNVQLVEAAPGTRAEIQIIATSGWPQATLGPVRPGGTARVELGSQAVTEGHDKTRIAAHELGHSLGLPDTKPGPCSQLMSGSTGGTTCKNATPNATERARVQSLYAGGFTFLVPADGRVLVDAP
>NC_020990|3003079:3063916|3031020_3031632_+|WP_003949695.1|DBSCAN-SWA
MSTDETSRTLLVTAHPDPGSLTHYIAERLSTALRPGAVEAADLHQEGFDPRFTSADRRAYQEGGGHPPDVVREQQRLDWATDLVLVFPVYWWSVPALLKGWIDRVFVNGWAFEYAATGGVLPKLQRLTTHLLPIAGADAGAYERHGYEMALRTQLTHGLIDYVGSQRGATAFVHDSEQPSTGAAVDHAVRTLASAVGAPVSRS
>NC_020990|3003079:3063916|3038094_3039855_+|WP_008405913.1|DBSCAN-SWA
MRKRSAATAAALITACAVTGALTGAAVATPGRVTDGNRAEKTVVATATRSVTHEENERVPEGARWTQHYFPSSDGSGTELHADVLLPADLPEGAKVPVIMSAGAYFGHSGEMEVEEEHAGPSERFQDLLEGADLFGKGYAFVMVDTRGFGGSTGCLDLGGPGDQADVKAAIDWSAKQSWSTGAVGMYGKSFDAYTGLLGNNAKNDALKAVVAQEPIWDLYQHLHSNGVPRPNSVQLPTSYNRIASLAQLPDEDEHYRTNSAYETKHPECLALNSFGPTIGDPEDPYWKDRSPAEKAKGTDTPLLFTQGIAETNTLPVGMQEFLHNHRGPQRAWIGPWDHVRGNDRTQEGKFAMGRATWFKETMSFFDEHLKDIDPKVTYPNYAVQDNLGNWRAEKSWPTANRSANLRLGNGSYLDSGAGSQPTPPEEETGRNAGSFFIWSEPLKAATRVTGTPRITLTARGEGNVMVKLHDVGPDGNAVAFDERVSRLDQDHLNISLKSTDWTLRAGHRLAVEIGSVRTGDWLDTPSKQKIQISNARLHLPLDHPAEDTATDGDRAPWIDTYTQINAAKPTPGPATFTVPPADTRR
>NC_020990|3003079:3063916|3004406_3004595_-|WP_003949727.1|DBSCAN-SWA
MRSSYADANEPEEAAVIAGHVTSLSSDVASKRTTERVRVVTERLKQLADVPEARAVLDVGKG
>NC_020990|3003079:3063916|3024863_3025538_-|WP_003949701.1|DBSCAN-SWA
MIRVLLADDQPLVRAGLSALLNAEKDVEVVGVAADGAEALDLATELVPDVACLDIRMPKMDGIDVAARICGPDASPAVPVLILTTFDIDDYVFRALEAGVAGFLLKDSDPEEILRAIHHIAAGHGTLDRTLTRRIVAEYVERRRLRPVTATRGIDVLTARERDILLLLAQGMSNEQIAGALVVEVTTVKSHLARMLPKLGVQSRLQAAVWAYQNRVVTVDDAPR
>NC_020990|3003079:3063916|3051585_3052116_+|WP_003949683.1|DBSCAN-SWA
MEPLSSSSEASAMPTLVSHLALMGTKEEVSSARRRIVAKVREWGVPLDDETADAIRLVASELITNAVVHGSGPITVTLSHSSGSLVIDVLDTNSKVPKSGCLEAEDEGGRGLVLVDFLAARSGWKRVQGGKHVWAEIALPKSGPADEAAVQGQFSGARSPSSRGRTVPSSLASAIA
>NC_020990|3003079:3063916|3055828_3057532_-|WP_003949677.1|DBSCAN-SWA
MIAAIKPAGSNTRGLLAYLYGPGRHDEHLDPHIVTGFAMLGMPDPGRNPDATLTQLAHHLDEPVHLRNSEFGKKITDHVWHCPVRAAPEDRHLSDAEWADIAQRIVEAAGIAPPGDDLGCRWIAVRHADDHIHILATTVREDGRRPKLHGSGIRVGDACRQIETDYGLRQLKEGDRTAGKRPTQAEMHKAQRLGWDQTSREWLQDRIRAAIPHAGNAEELLAYLEADGIAIKPRRGPSGDLLGYAAGRPGDLNKDGKQIFHPGGRIAPDLTLPKLKARLESTAPEEHPTARRQRPATPWHQATDALHQGMTDDTHAQAHITALGELIEATAQKAPGHSRAELRTAAQTFARAQRSQIRAEHQAAHTLRRAARDIAHTTTGPDGSAFAALLAALVWATIIAARWHEAKHHAHQAEAARQTLHHLHTAADHALAPVIDTLAARQPSQQARRTLAHDVRAAVPDHADRILTDPAWPALATVLADAEASGHKLHQLLKEAAAQRELTTARQPARVLITRIQHTSRNPAPNRRAEAARRKTTTWTPAMGAGTSLTQSTNPVAEPGQHRRLGR
>NC_020990|3003079:3063916|3025534_3026761_-|WP_003949700.1|DBSCAN-SWA
MTRSAATAVTTALSALALLWIIALLARDDPSLTGAPLGMAAWWGTAVTLVLQSVALLWGRHQVTATLGCVAGLCLVLAAVFPSGLFTVTALPVLVGAFLAGLTGAWRDVCRWALASGVLVSTAHFVNGSADGRTGGWGLVMQALLQAALVVGLPLLPASVIAAQRATRAAQQETLAAVTRERDAKIGEAIALERAAMARELHDIAAHHLSGISLMASVVARQTASAPGEAHSGALEIRKQSNAILDDLRRLVGLLRDVGHQDEGVKTLATLPHLIATARLTGAQVDFDLRSDERRKPGAGVSLLGQLAAYRIVQESLTNASRHAPGAPCVVTVDDRDPRTLRITVRNAPPGPQARPASRGTGYGIIGMRERSALIGGSFGAGPTDDDGWETRISIPRESGHHLPEQFT
>NC_020990|3003079:3063916|3004693_3004891_-|WP_015507438.1|DBSCAN-SWA
MTETPRWTASSYSSGEGGQCVEWAPAHALATGEFLVRDSKVQNGPHLTLSRESFAGLVALARARG
>NC_020990|3003079:3063916|3003813_3004329_+|WP_003949728.1|DBSCAN-SWA
MANPQVFFDIEANGTSLGRVTFELFADVVPKTAENFRALCTGEKGNGRQGKPLHFKGSGFHRVIPGFMCQGGDFTRGNGTGGESIYGEKFADENFQLKHDTPGILSMANAGPHSNGSQFFICTEPTPWLDGKHVVFGKVLDGMDTVKAIESHGSRSGKTSATLTISDCGQI
>NC_020990|3003079:3063916|3061544_3062246_+|WP_003949672.1|DBSCAN-SWA
MTQRRSHHGSSKADDEDDVPEWVDQVMATVAAEVRRRRKELGWSAQDLADRCAEIGHPIPRNVIANMESGRRSNLPLVDVMVLAEALNTPPICLLYPVGYIEDVQRLPLQDSTSTLDALRWFTGEETDLGADDDMLRYFRAHHAAQERLRSARRDEEYARYHAQTAPNADRKAEALRSQARAAETADDAEDRLRRVRAFIEEEGVTPPFLWPDLADVIDSSGSDPETSEENDL
>NC_020990|3003079:3063916|3061219_3061450_-|WP_037630553.1|DBSCAN-SWA
MRQNEDAGGAKGMSREELLGLPAAVDLETGNRALGLGRSKGYELAKRGQYPCKVLRLGNAYRVVTADLLALLGLAA
>NC_020990|3003079:3063916|3030079_3030922_+|WP_003949696.1|DBSCAN-SWA
MNTHTCLVVGATGRTGRRVAARLRLRGIPVRAASRSSQVHFDWSQPAGWDAVLHGIYAAYVVPPPVPGPVHAFAARAAAAGVRRLVLLSGRGADGWGGSMFGRNMVSAEEAVRGAPLEWTVLRASNFAQNFGEDVFHAPLLAGELALPAGDVPEPFVDVEDIADAAVAALTERDRHVRQVYELSGPRPVRFAEAVELIARASGRTLTYRQITCDAYVAELVGQGVSRHEADEVAEMFALMAGGSVSETTGDLTTVLERAPRTLEEYVVRAAAAGVWNAPQ
>NC_020990|3003079:3063916|3006216_3006405_+|WP_008405998.1|DBSCAN-SWA
MTPESQPSTPTNEPPTPCRTCQEFTLAEAVANGERDWSKATDCRVLRKRHQEAGECLGREAG
>NC_020990|3003079:3063916|3026781_3027762_-|WP_037629820.1|protease|DBSCAN-SWA
MTENRASLPRTPVPDRLPARLRAMARARPLTYFFLLANGLSWVAWVPYILSQNGLGIWDYRFPAILGTTQVLGVLPGAYLGPIGAAFAMTALVDGRTGLRAWTRRLWRWRVGGRWYAITLLSVPAGMLLTGLAFSGGQVAAPSAAALTAFVPMLLFQMITTGLAEEPGWRDFALPRLQSRFSPLRAAFVLGPLWGVWHFPLFLTEWGGYPEASWTRPLAFFTFCVAFNIVMSWVFNRTGQSLPLSMLMHVGVNTFASVMWSEMFPGLDGELALVAMGTGASVAAAVIVITTRGRLGHGPAVPPDHGDASPLARRAGYDRDLTMIEP
>NC_020990|3003079:3063916|3044679_3045405_+|WP_106428971.1|DBSCAN-SWA
MICGTTLRDRLVGLSHGSKSLLDTMEKGKLPPRMKGDVLDTHLAKMCAVLTDLLDLDLFHWYPTGEPAEPRQRELAATVVADRLCGAIADPIVRNAQERRQLALIEEWLLARGYTKKTHSASLPLNTMQPGTFSFRQNVVVGSDLPVNIPVDAVIQPHTPHSHKLPILIEAKSAGDFTNTNKRRKEEATKIHQLQLKYGNEISLTLFLCGYFNTGYLGYSAAEGLDWVWEHRIDDLEAAGA
>NC_020990|3003079:3063916|3013850_3014348_-|WP_003949715.1|DBSCAN-SWA
MLIREARTEDWDAIWPFFESIVRAGETFTYPLDLSREDAEGWWMVKAPSRTVVAVDDSGTVLGTAKMNRNHMGNGSHIASASYMVDPAHGGRGVGRALCTHTIDWARAEGYRAMQFNAVVETNTRAVKLYESLGFEVLGTLPEGFRHPGEGYVGLHIMHRSLLAD
>NC_020990|3003079:3063916|3012293_3012758_-|WP_003949717.1|DBSCAN-SWA
MQYTDAQLASQPAPYWTKLAYEATIGFVRRKQAEVGFTQPRFWMLRFLSANDVSEDGQGRTVEELRSAMVSFLRPEDDLAAEAEVLLASGWVTRDGDGRLWITEAGDAARADLKARAPEWGAEMHQGISEAEYATTLRVLMRLMRNTGAAVPAI
>NC_020990|3003079:3063916|3006401_3006620_+|WP_015507439.1|DBSCAN-SWA
MSGVESGPPEPEFNPLRYPPCACPLHRAEREPEQETDQEPRSEPGEDSPSLRELRALVTEENRLRRWLRGSS
>NC_020990|3003079:3063916|3040712_3042197_-|WP_051085199.1|DBSCAN-SWA
MAQLTLPQLERHLYAAADILRGKMDAAQYQDYIFGMLFLKRASDQFDVAQAALVKKLVAEGKSEEQAERISEARGAYKAHEFYVPEESRWSTIVGKSRTEPAEALNVALAQLENHNHQALDGVLSYISFTESRGGNTKLTKPVIQQLIDHFSEYRLSNEDFEFPDLLGYAYEYLIGEFADEGGKKGGQFYTPRSVIRMMNQLVKPQSGMSVYDPCCGSAGMLILAKEYVQDHDGDESHLSVYGQEDNGSAWAMARMNLLMHGVADGVIHHGDTLTDPQHVQGGQLQRFDRILTNPPFAQNYRRTGMKFAERMGYGWTPESGKKADLMFIQHVLAVLEADGIAASVMPHGVLFRGGEEQKIRRQIVEEGRLEAVISIGPNVFYGTGIPACILVLRGRDGAPEGRRDGVLFINADREVTAGRTQNLLEAQHAEKIVSAYEGWREIAGFARVVKFAELRVVPQMIFGSPRVWGRPLCGPPVYPVRARLCMRAMPSMA
>NC_020990|3003079:3063916|3029057_3029999_-|WP_003949697.1|DBSCAN-SWA
MDISSELFRGVRAHGSLFGSSTLSPPWSLHFVDGPPLTLCTVLTGAGWIVLDGYPPERLGPHDTVVVRGPATFTFVDDPATTVEPLVCSAECATPEQGGTRHRLGWHEPGEDGAGHGTTTLVIGAYPVSGEIGRRLLDSLPVVLRVPAGGDGDPVLDHLAVEVSRDEPGQQVVLDRLLDWMLVCTLRTWLDEPGRRPPAWWSAQKDPVAGKALRLLHAEPAAPWTVAALARRAGVSRSTLAKRFTELLGEPPLAYLTHWRMTLAADLLAEHPSATVASIARTVGYTDPFAFSVAFKRTRGVTPSAYRRATEAR
>NC_020990|3003079:3063916|3047474_3048639_-|WP_086014547.1|transposase|DBSCAN-SWA
MPKPYPQEFREDVVRVARNRGPGVTVEQVAADFGVHAMTLWKWMRRADIDDGVKPGTTGQESVELREARRRIKLLEQENEVSAAGGGVSVAGEPAGKRIYPLVKELAAGGVPVTVACRVLKLARQPYYRWLGAPVTGAEFEEAYRANALFAAHRDDPEFGYRFLADEAPQHGAVMADRTAWRICRGNQWWSVFGKKRGRTKKAGPPVHDDLVNRTFTATGPNRLWLTDISEYPTGEGKLYLCAVKDVFSNGIVGYSIDARMKSRLAVTALENAVARRQDVTGCILHSDRGSQFRSRKLVEALGRHRMAGSIGRVGAAGDNAAMESFFSLLQKNILDRRTWATREELRIAIVTWIERTYHRRRRQIGLGRLTPVEYETVMTTPALQAA
>NC_020990|3003079:3063916|3039993_3040764_+|WP_003949000.1|transposase|DBSCAN-SWA
MAGVITASEPSWIAPFSGLSPRQFGKLVTVLRREGADAVRKGRPWSLPLEDRALLVAAYWRTNLTMRQLAPLFGVSKSAADRIIDHLGPMLALQPRKRFAKDTVLIVDGTLVPTRDHTIAERSKNYRYSTNHQVVIDADTRLVVVVGRPLAGNRNDCKAWEESGAKAAVGKTLTIADGGYPGTGLVIPHRRERGQAGLPDWKEEHNKSHKQVRARVEHVFARMKTWKILRDCRLKGDGVHHAMLGIARMHNLALTG
>NC_020990|3003079:3063916|3005043_3005256_-|WP_003949725.1|DBSCAN-SWA
MSRAYGLRPDQWVKSTYSGGEGGQCVEWAPAHALATGEFLVRDSKVQNGPHLALSQEGFAGLVALAKSHG
>NC_020990|3003079:3063916|3043860_3044631_+|WP_003949000.1|transposase|DBSCAN-SWA
MAGVITASEPSWIAPFSGLSPRQFGKLVTVLRREGADAVRKGRPWSLPLEDRALLVAAYWRTNLTMRQLAPLFGVSKSAADRIIDHLGPMLALQPRKRFAKDTVLIVDGTLVPTRDHTIAERSKNYRYSTNHQVVIDADTRLVVVVGRPLAGNRNDCKAWEESGAKAAVGKTLTIADGGYPGTGLVIPHRRERGQAGLPDWKEEHNKSHKQVRARVEHVFARMKTWKILRDCRLKGDGVHHAMLGIARMHNLALTG
>NC_020990|3003079:3063916|3005252_3006083_-|WP_003949724.1|DBSCAN-SWA
MIDASPSQGDQPANGLEWFGRELAAALLHRGASQRQLADFTGYKEPYVSKAKNGKAMPSPAFAEGCDRFFNTSGSFSRLLAWISEGGHPGWFIPYINLEKQASRIEDYSNALIMGMLQTSEYAAATFRATHPRETEEQIKLRVEARLARRDVMTRDAPPMLWVILHESVLRTCVGGRAVMAAQLRSLASDAGNPHITVQVLPFTAGAPASSLPFTLLTPDDGATVLYSEARGQGHVSDSAAVVDDARTAYEHLRASARAPEESLALIRDISEEYAT
>NC_020990|3003079:3063916|3042864_3043365_-|WP_041826601.1|DBSCAN-SWA
MASTHLVILGERSALRWVLTEQRLAFPAGRARQSGVLRVGDEVLLYTTRGCFRNPTRDVGRIIGRGSVAAPVSVLTAPVRFGDREFTTGCGIQIQGLAPFLEGLSIRDLVHALDAFPNKRAWAVQLRRTTLALSAQDAELLHRELESRLLPYADAIGSYELLPAHP
>NC_020990|3003079:3063916|3015734_3016694_+|WP_015507442.1|DBSCAN-SWA
MPLRCALLNDHQGVATTAADWSPVLDRVELTSFPDHFGTEDELAAALADFDIVVTLRERVPFPASLFARLPRLRLLVASGMRNSAIDLAAARAHGVTVCGTDSHSTPPVELTWALILGLARNLVAENTALRTGGPWQSTVGADLHGRHLGVVGLGRIGSQVARIGAAFGMEVAAWSPNLTEERAAEHGVRLAPGLPELLADSDVVTLHLKLGERSRGIIGARELALLKPTAYLVNTSRAALVDHDALLAALNEGRIAGAGLDVFPTEPLPADDPVRTTPRLLATPHLGYVTERTYATYYREAVEDIAAHLDGTPVRVLG
>NC_020990|3003079:3063916|3031663_3033553_-|WP_003949694.1|DBSCAN-SWA
MALPTIISVEEFFAPPRRSRASISPDGTKIAYLAPWENRLNLWVGSVEAPEEARRVTSEDRNLLSYHWTDDPRWLLYTRDQGGDENSHLYRVDLDVPDAAAVDLTPFPGARITDLKLPTSRPGKAVFSSNSRNPAVFDLFELDIATGDLRMLAENTAGAAVTLFYGGSAGPLTSEVSERGDLRLSRWDESTQTSCHLAWFEGGDYPLGVYPLEVTPDGSGVLHGSYQDSDRLRVVRLDTVTGEETVVDSHPRYDLDTRARVFPSLPSPLIFSRRTGELIGVRYLGERQVIKALDPHFAEVLENLEKLSAGDLADISSDETGQRWVVSFTHDRDPGAAYYYDHSSGESRLLFRPRGHLDPEQLASMTPVTITSRDGLALPSHLTLPLGVEPHRLPLALLVHGGPWDRDSWGFNPLVQLLANRGYAVLQVNFRSSTGYGKSFMKAGIGELAGKMHDDLIDGVDWAVAQGYADPDRVAILGGSYGGYAALVGAAFTPDVFAAAVDIFGVSDLANFLRNQPEFVRPALAANWFRWVGDPADPHQEADMLTRSPISRVDQIRTPLLIAQGANDARVAQAESDNMVHALRARGALVEYILMGDEGHSIENPENLTAVYRAVERFLGEHLGPGRDG
>NC_020990|3003079:3063916|3059686_3061048_-|WP_078485261.1|DBSCAN-SWA
MRSDPAARACKPAAARRGAAQCNPRTPDPYSSPARAAWPATAVPGQPGAHLGPAQAAYATAEMHDGPADGSEADPARSLETIPDAEPTPGSDLLDELRSQIAQFVIPPSSEALNAVTLWVVATQLQPAWQHAPRLAVVGPAKRCGKSRLLDVLTETVHEPMLTINTTPAAIFRSINEEEPPTLLVDEADTIFGPKVAEKNEETRGLLNAGHQRGRYVTRVVGNDHTPHKFATFAMAAIAGIGDLPDTVMDRSVVIRMRRRAEGEKVKPFRSRRDIPALHELRDRIRAWALPLLEDAASLEPEMPVEDRAADTWEPLVIVADLAGGRWPRLARIACARMVAAEVAAEEDHPSGARILADIRRVFFAQREADSLSTEDLLHHLNADAEAPWGERGRYGLTSRELSGMLRNYDIRPGNVRMADRTQRKGYTRNKFLDAWRRYCPTVHPVDARRGES
>NC_020990|3003079:3063916|3016709_3017567_-|WP_003949711.1|DBSCAN-SWA
MLVLAVFFAVLGAASNAAGTAFQRKAASEVASGGGWRLLRELARKPVWLLGIAGVVGAALFQALALVNGPLALVQPVFVLELPFALLIGVPLLHRRLPREGWWAVAAVVVGLVAVLGAAAPAGARTDAPMTRWIPVLVGCLGAMALAVVASRVNRSPLFRAAALGCAAAVGNALTAALLKSATGTLADDGFIAFLTTWQTYGFAVTGVAAVLLLENALQAGPLAASQPALTIGDASVSLLLGVVVFEESVRGGWWVVPELAGVALIAWGVRELTRAVPHLRDLTG
>NC_020990|3003079:3063916|3057528_3058089_-|WP_015507453.1|DBSCAN-SWA
MAESAQRQGALGREVGAEGGPDQDELHTAQQQILRPAPATEPTAGERAPQSVQPTIRRFTGTKRTVRVGPLRFTGDEHAALQEAAAEHGYKGESGFTADIALAFITGRFTANLPLSEDRRRTHMFRAQVLRELNRIGVNVNQIARALNSDLTPPDVRDRLDELHHLLDLLAGALCEPAEAEKEQAA
>NC_020990|3003079:3063916|3054846_3055704_-|WP_015507452.1|DBSCAN-SWA
MTLSTSTGQAVDLRVQPVDTILDQVERSLQTRLDRDTVVRKRRSVGARTDRDTWVRIERRLVDKIGDQGWNGTECAARLEGVAQPEWQACVVWRDADEPVMWRADETELLPGDPIGTAVLSEDPKLPDEWWRAFSSSLDALAAQRTSRVASPDTETITQALVTGTIRAAFPNSLDTTVEQWVPAHADLNWANMSAPTFSLFDWEDWGNAPRGLDSASLWASSLAVPALADRVLRERRADFASRDGKLMTLFVCSKILGPDAHPQDPRLEPARHMAEQIVQDLQTD
>NC_020990|3003079:3063916|3021608_3021761_+|WP_162473210.1|DBSCAN-SWA
MSDLDKSAFAPEFLSFPAERRLHKPEMSATHCQHPPTDLPEIVRLLGLPP
>NC_020990|3003079:3063916|3062242_3063916_+|WP_015507455.1|integrase|DBSCAN-SWA
MKGSTYRRCSCRDAKTGKELGTSCPKRNSRNHCTYSVRQELSPREDGSRRSFSRGGYASLKAAQADLDHVRALLGLADSDDPEGTELIAEMLAEVSRERSPLPEVEETRRRLNSGQDLIGSLTVAEWLDRWLAGKRIRKSGLNRYETDIRVHLKPRIGSRRLDRLRVSHLSEMFTDIREANAQILEDNAQRRAALDELATVPWKGVGNRARRKAMKAAIDEMPPFRRVTGPATRLHVKATLRAALNDAIGQQIITFNPAAHVEIDPVRKPKALVWTDERVAKWEQTGEKPSPVMVWTPEQTGAFLDFVAGDRLYAMWHLIAFRGLRRGEACGQPWSETNLDTHSLTVSSQLVQDGWEVEASDPKTDSGSRVVALDDDTVDVLKHHRERQETARKEWGTAWVETGHVFTQEDGSWLHPGKVTDLFERLVAASGLPPIRLHDLRHGAATLMLAADIDIKIVSDTLGHSDTRITRDIYQSVLPHVGKSAAEATAKLIPLQRKAEAEKAARKAAKKEKARKAAAKAADVGKGSKGGGKPKRDKAKAQAKAAKKATRRKPTK
>NC_020990|3003079:3063916|3058414_3059269_-|WP_003949675.1|DBSCAN-SWA
MTAPHLTTSSPQTRDDVPAEGQRPKRADAERLVLRAGGIVIVVLTAGAFWLSYAHLADVAGQHGLGASPIRRWAWPATLDAFIVAGELLMLRAALRRTTDLWAVAVTVAGSVGSIALNVAGVSGADSERSVPLLDYVVAAVPPAAAMVAFGVLMRQIHQLVAPNDAPSSIGSVAVRNRLVGEHGEGRRQDAAAEVPQASGEERSESTPPVPEAKPVGGRPPKATIAELKAIGRAAGRQHGKLTRGLLRAAVKERNLTIGSARQTEVMESLRPELEAAGIKVSGG
>NC_020990|3003079:3063916|3050026_3051421_-|WP_050777417.1|DBSCAN-SWA
MASSLRATPQGDDGRADVPGEPLAVHPLAYVRQSRGWGKAEFARLMQAQGKSLGVPLATNRTTVWKWEQGQEPDADARHVIADLLRVPHERAQATAWPYWLPVWEVTGLSTPWNEAGTVEALTDLVGSGCLDRRGFLTITGVALTGLAASWAEAPSAFASALNGDRVTNTMVSTIEQRISTLRALDDELGGARLLEQARGDLALITGLLDAGRYTDAIRLRLYALAARVSHLTGWMAYDAGLRSAGQRYYIGALRSARTAGDDAFGAFVLAEMGVQVSEAGQTAERVDLISTAIDNAPRTLSPYTQSFLYLHKAEALSRDGDHQRAGVALNRATSHWGRHTEGEDPDWLDWFGEAQLKSTEGKVLLRAGQVERATSALETSVNRAAPRDMTVRTARLAEARLAGNDLEGALEAANRGAELLEDKVSSMRALGRLNEFSARLEPNTSVPAVREFRERLKALPVTT
>NC_020990|3003079:3063916|3034605_3035277_-|WP_008405917.1|DBSCAN-SWA
MQDTSSREAAVAREAGRGKETVLEQAGGVKGVVYSALPALVFVVANGVGGLKVGILAALLVAGGIAAQRLVRRESIQPALGGVFGVAVAAGVSWYTGSAKDFFLIGIWASLAGAVAFVVSVVVRWPLAGLIWNATTGKGVVWRADGRSRLYYDIATLVLAVIFGARFAVQQYLYQADEVGSLGFAKIAMGYPLLALGVLVVAWAARASDKRLKVAGLLPAKRT
>NC_020990|3003079:3063916|3019106_3019901_-|WP_031177928.1|DBSCAN-SWA
MTVGVDLAGRTGTTGVCRVTWGRRAVVELLPARDDDDLLAAMRSADKSGIDAPLGWPVAFAELVAAHRSGAELPALAHHEACADGRPGLGNTFTHRLTDDVAWKRTGAGRRRPLSVSVDKLGVLAIRGAGLLARLAEEGRAVPRDGSGAVAEVYPAYALIMWGIASEGTYKGKGEGAEAARGRVLAALEAGLGLDLSGEARRRCVADDHALDALISAVVARAVALGLTEGPATGDERALAPVEGWMHLPRRGVGLDEMRGPSGP
>NC_020990|3003079:3063916|3036167_3036605_+|WP_003949692.1|DBSCAN-SWA
MTTVFSRIITGELPGLFVWQDPEIVAFLSIAPLRPGHTLVVPRREVDRWTDIDGPLLTRCFEVAQAVGQGVQRAWNAPRAGLVVAGFEVPHLHIHVAPVWDMTDFDFSKAKQEEDPSALTGAAVKLRAALLELGYEQARGCTSGA
>NC_020990|3003079:3063916|3052871_3054068_+|WP_003949680.1|DBSCAN-SWA
MEHQLVSAVERALGWSGPEEIGKGFARGNIGDPDLVSRILTPNRLLDIAMRRSLSRPQFRCFQKGDEVHPAVYYTDSVSPRGQSIPMVNMRSLGRLLDEGATLILDQANVFDPTMEVACRALQWWSHERVQVNAYLTTNDAAGFPLHWDDHDVVIVQLAGEKEWEVRGTSRPAPMYRDADPNSTPTDEIVWSGVMRTGDVMHIPRGHWHQATRTGSGSGKSLHVTFGVTKRTGASWLAWLGDWCREQEIFRHDLDRRDPVGGQALLEAATRLIGERSPADYLAAYEQATTLPRHVPYLDILAPLDTVVCTTHFPPQIHESGETVTVVVSGKRLTLAAKAVPALRMLLSGQPVSLERAAALVGADVAEVAEILVKEELCATLTPELSSGYTGLVMDVAS
>NC_020990|3003079:3063916|3048780_3049953_-|WP_003949685.1|DBSCAN-SWA
MTVIGGEVAAGFEPVREAFAENFARNGDIGAAVCVYRDGHPIVDLWGGIADPRTGRPWTRDTLQLVYSATKGATATAAHLLAQRGELDLDAPVATYWPEFAANGKADIPVRWVLSHQAGLVALDQPVPLNDALAWRPMAAALAAQQPAWTPGTAHGYHGRTWGWLVGEVIRRVSGRTPGRFFADEIATPLDFDFFIGLPAHERERVSHMVHSKPAVDLTTVAPELVPEELRDQVAAWSDPDSFSNRAYMVTDPAAIDFNSPEVQAAELPASNGIGTARGLARMYAALIGEVDGTRLLTPEALTLAIKEQAAGMDQVLVAPSRFSSGYQLPTEDNPMMGPSAFGHNGRGGSLGFADPEHGIAFGYAMNHIISGPDDVRAVSLIDAVLKSLR
>NC_020990|3003079:3063916|3017655_3018594_-|WP_003949710.1|DBSCAN-SWA
MDSVPVPVPVPVPVVSVKPLGLSVPGRREELRVRVSAPVTGRGLPVVVFAHGFGASSEGYGPLADYWAARGFVVVQPTHLDAKTVGLAADDPRRPGLWRYRVEDVRRVLDRLDVLVGQVPGLAGRVDQERIAVAGHSFGGQTAGVLLGLRVLDPETGRAEDLSDPRVRAGVLLATAGRGGDALTPFAAGNLPWLRGPEFAHMTAPALVVAGDRDASPLTVRGPEWTADPYVLSPGEKSLLTLFGAEHFLGGISGYEVAETTDENPARVALVQEVTTAYLRHVLGVGSQEWEAVRRALGGEAHPLGRLVSKRG
>NC_020990|3003079:3063916|3019932_3021201_-|WP_015507445.1|DBSCAN-SWA
MKDEVQLVSDGDGLAVIGGREDVERFLVSEGLVGRKVGSGWIKGVVGAGAAVVKEGVDGDAGVSGRWVKLTAESAEQVKKYGLRESAATGVSTGVLKGDRGQIKGFVEFARGSRSVVGSPVALANVAKLLAQVAMEQAMDEISEYLDAIDAKVDDVLRAQKDGVLSRMIGRGLVIEEAMTVRRQRGGVDEVTWSKVQGGPATIAETQAYALRQLDALAEKMERQAKIGELAATVREAEPAVREWLAVLARCFQLQDAVAVLELDRVREVSPEELNGHRLGLREARRDRQELILRCTDRLVTRMNVAAGAANAKVLLHPAKSPAVVEASNQVVVGVHEFQERVADRAGRRYTEARRWREAAVQARDRALETGAMGVAAARAVGNETLDRAGTVRDKLASGIAERARRLRGDRAEDEGKSEGAG
>NC_020990|3003079:3063916|3009379_3010852_+|WP_003949719.1|DBSCAN-SWA
MTSSATPETASLFPALHTPPVPPKPALRFGDRTLEYGEVARLAGALARELPLGRRVAVWATPSLETGVAVVAALLAGVPAVPLNPKAGARELAHILADSDPALVLAAPGEVLPEELAGLARRDVATDPEALPGAVALPAEPGPEAPALIVYTSGTTGPPKGVVLPRRALTSTLDALQDAWQWTADDILVHGLPLFHVHGLILGVLGPLRRGGSLVHLVRFSTDGVRRALEEGATLMFGVPTMYHRIAEEAAGDPALAAALARARLLVSGSAALPVHDQERIAAATGRRVVERYGMSETLMNTSVRADGEPRPGTVGVPLAGVALRLVEDDGSEIAEWDGETVGEIQVRGPNLFTAYLNRPDATAEAFDGDWFRTGDMAVREPDGYVRIVGRRATDLIKSGGYKIGAGEIENALLDFPGVREAAVTGEPDPDLGERVVAWLVTDGGPVDAQAVADHVARQLAPHKRPRVVRHLDALPRNDMGKIMKRALHG
>NC_020990|3003079:3063916|3010844_3012209_+|WP_015507441.1|DBSCAN-SWA
MADRDALTARALIASLDPDYVELGFFGPEFTDGPLEWSGYGAARERARARTGERESVVCATGRVRPGSGAAPAPEAVLIAFEFGFLGGSLGEATGDRIEAAYAHARAHRLPVVSLVATGGSRMQEGMRALTQLQRVARQTVLTRRAGLPQLAVVRDPTTGGGWATLAAGADVVLALPGAQVGFAGSRVRPADADPWAYTAEGQHAAGHIDALTEPVDLSDVLGRWLALLAGQAAPARRAEPPHALTTGPLPADGAEAVRRTRSLERPRADAYLDAYFDWREEIRGDRTGATDPGMRCGFGHRDGRTVAYAAQCGTATRPAGFRTAARLVRTADRLGIPVLTLIDTPGAANDAAAEQGGAGPAIADLFAAVAEAEVPVTSLLVGEGGSGGALALAAPGHLWVTPDSYFSVIAPELAAAILKRPPEEIPATADALRLRPQDAVELGVARGVVPGPA
>NC_020990|3003079:3063916|3015075_3015702_+|WP_003949713.1|DBSCAN-SWA
MSATPGPLSDVSPTTLADLLGREQVMDFGLRTLCPTPPRVAGPAFTVRCAPGDQLMLHAAIYRAAPGSVLVVEGGGTEYAVAGGNVCAVAQRRGIAAFVVDGVVRDLAEIRASGFPVFARGVVPKPGTKKAAFPLNGEVRCGGVTVRAGDLVVADEEGVVVLPAARQDELLQAARAKEAKEAAQSLDAWETDHYARIQQALDAQDFTG
>NC_020990|3003079:3063916|3014491_3014968_+|WP_003949714.1|DBSCAN-SWA
MPATEAVPAAYRHAVVPHLLVDDADAALTFYQRAFGAEPRFRLDGDQGEVVHAELTVAGAVMMLGDARDTLRSPAALGGTPVILHVYVPDVDALTARATAAGAELLEGPADQFHGDRTAMLRDPFGHLWIFLTHLEDLTPEQIAERLAEADGTAGATG
>NC_020990|3003079:3063916|3018697_3019075_+|WP_003949709.1|DBSCAN-SWA
MMRIGELATRTHVSVRALRYYEEHALLTAERTPSGQRHYPESAVARVHLIQQLYAAGLSSRTIRDLLPCVLDGRATPELLHRLTAQRDHLTTKLAALTATRDTLDRVIANAETSLRTGEACGGGE
>NC_020990|3003079:3063916|3054001_3054859_+|WP_037629818.1|DBSCAN-SWA
MRDTDPRVVLGLHRSRHGRRLLIGALDLGVTALDTSTNYLRFRSHEVLARVADDLLPKFHLSTKVGYFPGISGAEHSLAPERLHSAVEEAARDLGREPDLVFLHNPEHSLTPGTDRSREALAEACTALASATSRGLCGAWGIATWNPTPLPPLVDASAPTPSTLMVRAGLLVGAGTLDAAEALMEAWGLGTGAMWGMSPFGGSTKAPVWARADARVFLRNGSGYSRAQAAFRMAYQLPNVSAVAVGTDEPAHLGELVGALAATPDEHAVAEYRTLLRDRPRTQSV
>NC_020990|3003079:3063916|3007949_3009278_+|WP_015507440.1|DBSCAN-SWA
MSAELLSILVLAVLFVVGTTRSVNMGALAFAAAFGVGTLAAGLDADGIFAGFPGDLFVVLVGVTYFFAIARANGTTDWLVHAGIRLVRGRIALIPWVMFTVTGVLTAIGAVSPAAVAIVAPLAMGFAARYGIKPLLMGALVVHGAQAGGFSPISIYGSTVNGILEREGLPGSPIALFLASLFANLAIAALLFVALGGLRLRGRDLGDLGDEEAKEAKEGGGGSGGTGGTVTGTRARTTPDADLLRLTPARIATLVGLVALVVAVLVFDLDAGLTAITLAVLLAVVWPEDSKAAVAHITWPTVLLICGMLTYVAVLQEMGTIDWAGEHVGSIGIPLLAALLFCYIGAVVSAFASSVGIIGALIPLAVPFLEQGEIGVVGMVAALSVSATVVDVSPFSTNGALVLAAAEDTDRERFFRQLMLYGGAVTLLAPLVLWLALVVPGL
>NC_020990|3003079:3063916|3043572_3043848_+|WP_110034217.1|DBSCAN-SWA
MINADKPHRWNDDVQASVRLYNQWFLDAAPKAYRDTRQLTIDEVEQAFQRTANMTSITPEVLKAHPKTLATLRMSTAPPIAKGCPVTAGHR
>NC_020990|3003079:3063916|3006968_3007676_-|WP_003949721.1|DBSCAN-SWA
MTDDALRPMGRTRLYEQVLERLRAYAAEHRLAAGDRLPAERDLAQRLGVSRASVKQAVVVLEVQGLVETRHGGGTYLLRDTLDHEPVERLVERRRRLPDVLEAREALETKLAELAATRRTETDLTALRAALAHMAGEIASGGHGEEGDRLFHAAVTEAGHSPLLAEFMASLTDQITESRRESLRQPGRPDRSLAQHHAILDAIEAGEAKRAAAAMRRHVRTVAKVRLLEWEPGER
>NC_020990|3003079:3063916|3021874_3022348_-|WP_003949705.1|DBSCAN-SWA
METNDPLERTELTFLLGMAFQLVLSEFVSRLDSAGYAELRPMHGLVFQVLRGSGATSSELAEQLGVTKQAAGQILDDLEKRGYVERQPHPAGGRRKLVVLTAKALEHLVVAGRILHELEAQLTKQLHEVGLQVPRTELAAITRTLAGDSIPPWRPIW
>NC_020990|3003079:3063916|3022421_3022796_+|WP_003949704.1|DBSCAN-SWA
MYVVSESEQRTTTTPAGAMFGLAGPSQGSAEVSTWRVELGADTSTPVHIIDREQVWMPLSGEFEVEVDGKTEQVKAGQALVLSAGAVRQLKAVGGPAEALVTMVVGGKAMMPGSDKKIPLPWAE
>NC_020990|3003079:3063916|3045397_3047161_+|WP_003949688.1|DBSCAN-SWA
MHSEAREAEARRLLLQETLDAERTFLERNQWGQFATPPSLAGEIMRYTIDLHEETRINFLEPSCGSGSFFSALLRNLGDKKIEHAVGVELDPRFSKAASDLWTGQGLRVIEGDFTSPSLVSGPVASLLVANPPYVRHHHLGIDQKRDLVARCADQLGIKPSGLSGLYLYFVLLSHRLLRADAVSTWLIPSEFMDVNYGTALKEYLATRVQLVRIHQYDAAEVQFDDALVTSSVVVFRNSPPRPGHTAEFSFGGTLSEPKVTHQIPSAALTPEAKWSRYVTGVMPADINLKQTGPKLSDFFKIRRGLATGSNAFFIIPRSEAERLGIKRNFLRPILPSPRKLKGDAITADASGWPDIPEQLALLDCPLPIEDLLLENPALAAYLSTADEKIRGGYLVSKRSPWYKQEQREPAPILLTYMGRGKDDQHPLRFIRNDSDAVATNMYLMLYPTALLQRYLAGDPERIKQVHKALLAITAADLRGGGRVYGGGLHKMEPKELAALPADGIATLDPVLREDISMVSVPPRKRTGRPQMPGPSASEVRAWARANGVCVPDRGRLRPEVWDAWRQAHAGEASPLNIDAGDQVALW

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003949729.1|3003079_3003658_+|protease	snapalysin family zinc-dependent metalloprotease	NA	NA	NA	NA
WP_003949728.1|3003813_3004329_+	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	3.5e-47	53.3
WP_003949727.1|3004406_3004595_-	hypothetical protein	NA	NA	NA	NA
WP_015507438.1|3004693_3004891_-	DUF397 domain-containing protein	NA	NA	NA	NA
WP_003949725.1|3005043_3005256_-	DUF397 domain-containing protein	NA	NA	NA	NA
WP_003949724.1|3005252_3006083_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_008405998.1|3006216_3006405_+	hypothetical protein	NA	NA	NA	NA
WP_015507439.1|3006401_3006620_+	hypothetical protein	NA	NA	NA	NA
WP_003949721.1|3006968_3007676_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_015507440.1|3007949_3009278_+	hypothetical protein	NA	NA	NA	NA
WP_003949719.1|3009379_3010852_+	acyl-CoA synthetase	NA	NA	NA	NA
WP_015507441.1|3010844_3012209_+	acetyl-CoA carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_003949717.1|3012293_3012758_-	hypothetical protein	NA	NA	NA	NA
WP_003949716.1|3012919_3013879_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003949715.1|3013850_3014348_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003949714.1|3014491_3014968_+	VOC family protein	NA	NA	NA	NA
WP_003949713.1|3015075_3015702_+	RraA family protein	NA	NA	NA	NA
WP_015507442.1|3015734_3016694_+	D-2-hydroxyacid dehydrogenase family protein	M1I4S0	Paramecium_bursaria_Chlorella_virus	1.5e-14	24.3
WP_003949711.1|3016709_3017567_-	hypothetical protein	NA	NA	NA	NA
WP_003949710.1|3017655_3018594_-	hypothetical protein	NA	NA	NA	NA
WP_003949709.1|3018697_3019075_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_031177928.1|3019106_3019901_-	DUF429 domain-containing protein	NA	NA	NA	NA
WP_015507445.1|3019932_3021201_-	hypothetical protein	NA	NA	NA	NA
3021344:3021386	attL	NA	NA	NA	NA
WP_162473210.1|3021608_3021761_+	hypothetical protein	NA	NA	NA	NA
WP_003949705.1|3021874_3022348_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_003949704.1|3022421_3022796_+	cupin domain-containing protein	NA	NA	NA	NA
WP_003949701.1|3024863_3025538_-	response regulator transcription factor	NA	NA	NA	NA
WP_003949700.1|3025534_3026761_-	two-component sensor histidine kinase	NA	NA	NA	NA
WP_037629820.1|3026781_3027762_-|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003949697.1|3029057_3029999_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_003949696.1|3030079_3030922_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_003949695.1|3031020_3031632_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_003949694.1|3031663_3033553_-	S9 family peptidase	NA	NA	NA	NA
WP_008405917.1|3034605_3035277_-	DUF3159 domain-containing protein	NA	NA	NA	NA
WP_003949692.1|3036167_3036605_+	HIT family protein	NA	NA	NA	NA
WP_008405913.1|3038094_3039855_+	CocE/NonD family hydrolase	NA	NA	NA	NA
WP_003949000.1|3039993_3040764_+|transposase	IS5-like element IS112 family transposase	NA	NA	NA	NA
WP_051085199.1|3040712_3042197_-	SAM-dependent DNA methyltransferase	A0A220A2U4	Liberibacter_phage	4.2e-69	37.0
WP_041826601.1|3042864_3043365_-	hypothetical protein	NA	NA	NA	NA
WP_110034217.1|3043572_3043848_+	XamI family restriction endonuclease	NA	NA	NA	NA
WP_003949000.1|3043860_3044631_+|transposase	IS5-like element IS112 family transposase	NA	NA	NA	NA
WP_106428971.1|3044679_3045405_+	XamI family restriction endonuclease	NA	NA	NA	NA
WP_003949688.1|3045397_3047161_+	modification methylase	NA	NA	NA	NA
WP_086014547.1|3047474_3048639_-|transposase	IS3 family transposase	A0A2P1JR32	Mycobacterium_phage	2.8e-20	34.4
WP_003949685.1|3048780_3049953_-	serine hydrolase	NA	NA	NA	NA
WP_050777417.1|3050026_3051421_-	hypothetical protein	NA	NA	NA	NA
WP_003949683.1|3051585_3052116_+	ATP-binding protein	A0A1J0MCT1	Streptomyces_phage	9.8e-05	37.2
WP_003949680.1|3052871_3054068_+	cupin	NA	NA	NA	NA
WP_037629818.1|3054001_3054859_+	aldo/keto reductase	NA	NA	NA	NA
WP_015507452.1|3054846_3055704_-	hypothetical protein	NA	NA	NA	NA
WP_003949677.1|3055828_3057532_-	hypothetical protein	NA	NA	NA	NA
WP_015507453.1|3057528_3058089_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_003949675.1|3058414_3059269_-	DUF2637 domain-containing protein	D7NW84	Streptomyces_phage	5.0e-35	56.3
WP_078485261.1|3059686_3061048_-	DUF3631 domain-containing protein	NA	NA	NA	NA
WP_037630553.1|3061219_3061450_-	hypothetical protein	NA	NA	NA	NA
WP_003949672.1|3061544_3062246_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015507455.1|3062242_3063916_+|integrase	site-specific integrase	X5JB41	Clostridium_phage	1.4e-20	29.0
3064043:3064085	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_020990|3322761:3380877|DBSCAN-SWA
CGTGATTGACCTTCGCCTGCTTCGTGAGGACCCCGACCGTGTGCGCGCCTCCCAGCGCGCCCGTGGAGAGGACGTCGCGCTCGTCGACGCCCTGCTCTCCGCCGACGAACGGCGCAGGTCGTCCGGCGTCCGCTTCGACGAGCTGCGCTCCGAGCAGAAGTCGCTCGGCAAGCTCATCCCCAAGGCCACCGGTGACGAGAAGACCGAGCTGCTGAAGAAGGCCGGCGAACTCTCCGCCGCCGTCAAGGCCGCCGACGCCGAGAAGGACGAGGCCGACCAGGAGGCCAAGCAGCTCCTGCTCCGCCTGGGCAACCTCGTCCACCCCGACGTGCCGGTCGGCGGCGAGGAGGACTTCGCCGTCCTCGCCAAGCACGGCACCATCCGCGACTTCGCCGCCGAGGGCTTCGAGCCCCGCGACCACCTCGAGCTGGGCGAGGCCCTCGGCGCCATCGACGTCGAGCGCGCCGCCAAGGTCTCCGGCTCGCGTTTCTACTACCTGACCGGCGTCGGCGCCCTGCTGGAGCTGGCCCTGGTCAACGCCGCCATCGCCCAGGCCACCGCCGCCGGCTTCACCCCGATGCTGACGCCCGCGCTGGTCCGCCCGCGGGCGATGGAGGGCACCGGCTTCCTCGGCCAGGCCGCCGAGGACGTCTACCACCTGGAGAAGGACGACTTCTACCTGGTCGGCACCTCCGAGGTCCCGCTCGCCGCGTACCACATGGACGAGATCATCGAGGCCGACAAGCTGCCCCTGCGGTACGCCGGCTTCTCCCCGTGCTTCCGCCGCGAGGCCGGTACGTACGGCAAGGACACCCGGGGCATCTTCCGCGTCCACCAGTTCGACAAGGTCGAGATGTTCTCGTACGTCGAGCCGGAGGACGCCGAGGCCGAGCACCAGCGGCTGCTCGACTGGGAGATCCAGTGGCTCCAGAGCCTGGAACTGCCCTTCCAGGTGATCGACGTGGCCAGCGCCGACCTCGGCTCCTCGGCCTCGCGGAAGTTCGACTGCGAGGCGTGGATCCCGACCCAGGGCAAGTACCGCGAGCTGACCTCCACCTCCAACTGCACGGAGTTCCAGGCCCGCCGCCTGTCCGTGCGAATGCGCGAGGGCAAGAAGGTCCAGCCGCTGGCGACCCTCAACGGCACGCTGTGCGCCGTCCCGCGCACCATCGTCGCCATCCTGGAGAATCACCAGCAGGCCGACGGCTCCGTGCGGGTGCCGGAGGTTCTCCGCCCCTACCTCGGCGGACGCGAAACCCTCGACCCGCAGTAATCACCCAGTCTGGAGCCGTTCACCACGTGAGCCCCGTCCGTCCCGCCCCCGTGTTCCCGTACAAGCTCGTCGCCACCGATCTGGACGGAACGCTGCTGCGGCCGGACGACACGGTCTCCGAACGCACCCGTGAGGCACTCGCCGCGGCCACCGCGGCGGGTGCCGCGCACATCGTGGTGACCGGCCGCTCCGTCGCCTGGACCCGCCACGTCCTCGACGACCTCGGCTACGAGGGCATCGCCGTCTGCGGCCAGGGCGCGCAGGTCTACCACGCGGGGGAGCAGCGGCTCCTCACCTCGCTGACGATGGACCGCCGGCTCGCCGTGCTGGCCATCGAGAAGATCGAGGCGGAGACCGGCCCGCTGCACCTGGCCGCCGCCCGGGACGGGCTGCACGGCGAGGTCCTCATCGGCCCGGGCTACCAGGTCCAGGACGGCCCCCTCGCCTCGGTCCCCTCCACCGACCGGGACAGCCTGTGGGCCGAACCGATCAGCAAGGTCTACCTCCAGCACCCCACCCTGGGCGACGACGAGCTGGCCGCCGCCGCGCTGCGCATCGCCGGTGACCTGGTCGGGGTCGTGATGGCCGGGCCGGGCGTGGTGGAGCTGCTGCCGCTGGGCCTCTCCAAGGCGACCGGGCTCTCGCTGGCCGCCCGGCGCCTGGGCACCAAGGGCGCCGAGACCATCGCCTTCGGCGACATGCCGAACGACATCCCGATGTTCGGCTGGGCGGGCCACGGCGTCGCCATGGCCAACGCCCACCGCGAGCTGAAGGCCGTCGCCGACGAGCTGACCACCTCCAACGCGGAGGACGGCATCGCCGTGGTCCTGGAGCGCCTGCTCACCGGCTGACCTCCCGGCTCACTCCTCCCCGGCCACCGTCAGGCTCCGCAGCTTCTGCCCCGCGTACCAGGTGGCCAGTACGGTCGCCGCCACCAGCAGGATCACGGCGGTCGGCAGCGCCACGTCGGAGGTGACGGCCTCGCCGCCGGTCACCTTCTCGGCCACCGCCAGGGCCCACTGCTGCACGCTGAGGGTGCGGGCTCCGCTGATGAGGGAGGCGAAGAGCCCCTCCCAGATCAGGGCGTAGACCAGGCCGAAGACCACGGCGTGCCGGGTGACGGTGCCCAGCAGGAGGAAGAGCGCTGCGTAGGCGATGGAGGCGACCAGCGCCGCGACCGTGTAGGCGACGGCGAGCTGGCCGCCGTTGCCGTTGAGGATGAAGCCGGCGAGCAGGGTCGGTATGGCGGAGAAGGCCATCGTCACGCCGATGGCGACGAACAGCTTGGTCAGGATGATCGTGGGCCGCTTGATCGGCTTGGCCAGCAGGTACACCACCGAGCCGTCGTCGATCTCCGGCGCGATGGCGCCGGTGCCCGCGACGACACCGATGATCGGCACCATGACGGCGAGCGAGAACCCGCCGAGGACCGCTTCCGCCGTGCTGTCGTCGGCTCCGGTGAGCAGCCGTACCGCCGCCGCAATGACGAGGAGCAGCGCAGGGAGGACGAAGAGGATGAGGGCCCGGCGGCGGCCGAGCAGCGCCCGGTAGGTGAGCCGGGCGACCGTGGGGTCGTACATCGCTGAAGGCTCCTTACGCCGCGACGAGATAGGAGAAGACCGATTCGAGGGACTCGTCGGACGGCGAGACGGCCAGCAGCCTGATCCCGTGGTCCCGGGCCACCCGGGGCAGCAGCGCGGTGAACCGCCCGAAGTCGACCGCCTGGACGCGCAGCATCCCTTCCTGGGTGTCCACCTCGATGCCGGCGGTGGAAGGGTCCGCTATCAGCGCGGCGGCCAGGGCCCGGTCGTCGCTGGAGCGCACCACGTACTGGTGCGGCCGGTCGGTCATCAGCCGCCGGATGCGGCGGAAGTCGCCGGAGGCGGCGTGCCGGCCGGCGACGATCACCTCGATGTGCGAGGCGAGTTGCTCGACCTCCTCCAGGATGTGCGAGGAGAAGAGCACGGTGCGGCCCTCCTCGCCCATCCGCCGCAGCAGTTCCATGAGCTGCATGCGCTGGCGGGGGTCCATGCCGTTGAACGGCTCGTCGAGGAGGAGCACGGAGGGGTCGTGCACCAACGCCGAGGCCATCTTGACCCGCTGGCGCATGCCCTTGCTGTAGGTGGCGATCTTGCGGTCCTGGGCGTACTCCATGTCGACGGTGGCCAGCGCGCGGGCGGCCGCGGCGGCGTCGAGGCCGTGGAGTTCGGCGTTGGCGACGACGAACTCCCGGCCGGTGAGGAAGTCGTACATGGCCTCGCGCTCGGGGACGATCCCGATCTGCCGGTAGACGGACTCGTTCCGCCAGACCGCGTCGCCGTCGAGGGTGACGGTGCCGGTGGAGGGGGCGAGGAAGCCGCCCATCATGTTGATCAGCGTGGACTTGCCGGCGCCGTTGGGCCCGAGGAGGCCGGTGACGCCGGGGCCGATCGTCATGGTGATGTCGTTGACCGCGACGACGTTCCCGAACCAGCGGGAGGCATGGTCGATGGTGAGGGTGGTCACAGTCCGGCCTTCCGGTAGCGGCGCATCAGCAGGGCGTAGCAGCCGGCGATGAGGCCGAGGACGACGAGGAGATGGACAGCGCCGCCCGCCGTGGACGGTCCGGCCCCGCCCGGGTAGGCCGAGGTGGCGCCGAGGAAGGCGGTCTGCACGCCGTCGATCAGGGTGATGGGGGAGAAGAGGCCGATCCAGCCGACCGCCTCGGTGTTGCCCTGCTGGAAGGCGATGGCCTGGACGGTGGAGACCGCGCCGTAGGTGATGGTGAAGACCGCGATGACCGCGGCGATCCCGAAGCCGCGGCGCGGCGTGACCGCCGAGACCACCAGGCCGATGCCGGCGAAGAGCAGGGAGAGCAGTGCCACGGAGACCATGCCCTGTCCGAATCCCGCCGTCTGGTCGGCGAAGTCGAGTTCGGCGAGCAGCGCGCCCGCGTAGAGCACCAGGAGCGGGACGGCGGTGAGGAGGAAGAGGGCCGAGGCCATCGCCGCGTACTTGGCGAGGACGTAGTCGACGCGCTCGACGGGGCGGGAGAAGTAGAGCGGCACCGTCTTGAAGCGCAGGTCGCGGGAGACCGACTGGGGTGCCTGCGAGGCCACGTAGAGGCCGATGACGGCCTGCATGACGACGGCGTAGCGGGTGTAGTCGACCGGGAGGGTCTTGAGTCCGGCGGTGACCGTGACCGCGACCATGATGGCGGCCGGCAGGCACATCACGGCGAAGAGGAGCATCGGCAGCACCTTGGACTTGGCCGAGCGGCCGAGGCCGTAGGCGCCGCGCAGGCTCTGGGAGTAGAGGGCGCGCCGGGCGTGGGAGCGGCCCAGGCGCGGGCCGTCGTACTTCCGGTAGCCGATGTTGTGGATCTGTGTGCTGTCCACGGTCATGACCGACCGCCTCCCGCCGTGGGTCGGAGGGACTCCGCCGCGGCGGCGGGCGGAGGCTCTGCTGGGTCGTGCTGCGGGGGCTGCCCGGTGCCGGCGGCGTCCGCCTGGAAGACGTCGGCGATGTGGCGGCGGCCCTGCTCCATGCGGACCAGGCCGAGGCCGAGGTCGACGACGAGGTCGCGGACCAGGTCGCGGGTCTCGTCGTCGGCCTCCTCCAGGAGGAGGCTGTGGCCGGCGCCGGGGAGGACGCCGCCCGAGCCGGCCGTGACGCCCCGGTCGCGGAGGGCGGCCAGCAGCGCGGCCGTGCCGTCCGGGTGCGTCTCGGTGTCGGTGACCTCGACCGCCAGCGTGGTGGTGGCGCCGGTGAAGTCGCGGGTGGAGCTGGAGCGGAGCAGGCTGCCGCCGTCGATGACCACGACGTGGTCGCAGGTGCGCTCCAGCTCTCCGAGGAGGTGGGAGGTGACCAGCACCGAGATGCCGAAGTCGGCGTGGATGCGGCGGATGAGGCCCAGCATGTCGTCCCGGCCGACCGGGTCGAGGCCGTTGGTCGGCTCGTCGAGGAAGACCAGGTCCGGGTCGTGGACCAGGGCCTGCGCGAGCTTGACGCGCTGCTTCATGCCGGTGGAGTAGCCGCCCATGGGGCGGTAGCGCTCTTCGTAGAGGCCCACGTGGCGCAGGGTGTCGGCGGTGCGCTCCCGGGCGGCGGTGGGAGGCAGGCCGGACATCCGCGCCATGTGCACGACGAACTCGGTGGCCGAGACGTCGGGTGGCAGGCAGTCGTGCTCCGGCATGTATCCGACGCGCTCGCGGATGGCGCCGCCGTGGGTGGAGACGTCGAGGCCCAGCACCTCCGCCCGTCCCTCGGAGGCCGGGGCCAGGCCCAGCAGAATCTTGATGAGCGTGGACTTCCCGGCACCGTTGGACCCCACGAGGCCGGTCACTCCGGGCCCGACGTCCATGGTCAGCCGGTCAAGCGCGGTCACCTTGGGGTACCGCTTGCTCAGGCTTTCGGTCGCGATCACAGTCACCCCTCGAACGTAGTGGTGCGCGCCACACAGGTCGTCAGACCACGGGGTTGTCCTCGTCTCAGACTCCGGTATTACGAGCCCGTAAGGGGGCCGTACCCGGGTACGGGAGCGCGTCGGGGTCGCGGAACGGAGCGTGGAGCACACGTGTGTGAACGCGGCCCACTATTGGAAGAGTTGTCCACAAGGCTGGTGCACACCTATTGACGGGGCCGCGCCTGGTTGCCAGATTCGTCGGTGCCACGGTGCGTAATCCACCCGTCGCGACGGACGAGAGAGACGGAGTACAGGTCATGGGGGGTCTGAGCGGCGCGCGTGAGCGCTCGGTACACACAGGCGGCGTGGAGCTGCGGGTAGCGGAACTGGGCGACGCGAGCAGGCCCACCGTCGTCCTGGTCCACGGCTACCCGGACTCCAAGGAGGTCTGGTCCGGCGTCGCCGCCCGCCTCGCCGACCGCTACCACGTGGTCCTCTACGACATCCGCGGCCACGGCCGGTCGACCGCGCCCCGCCCGCTGCGCGGCGGTTTCACCCTGGAGAAGCTCACCGACGACTTCCTCGCCGTCGTGGACGCGGTCAGCCCCGACGCCCCGGTCCACCTCGTCGGCCACGACTGGGGCTCCGTGCAGTCCTGGGAGTTCGCCACCGTCGAGCGCACCCGCGGCCGCGTCGCCTCCTTCACCTCCCTCTCCGGGCCGTCCCTGGACCACTTCGGCCACTGGATCAAGAAGCGTGCCGCGCGCCCCACCCCGCGCCGCCTGGCCCAGCTCGTCAGCCAGGGCGCCAAGTCCTGGTACGTCTACATGCTGCACACCCCGGTCCTGCCCGAACTGGCCTGGCGCGGCCCGCTCGGCAAGCGCTGGCCGCGCATCCTGGAGCGGCTGGAGAAGGTCCCGGCGGGCGACTACCCGACCTCCTCCCTCGGCAACGACGCCGCCCACGGCGCCTGGCTCTACCGGGACAACGTCCGCACCCGGCTGCGCCACCCGCGCCCCGACCCGTACGCCCACGCACCGGTGCAGCTGATCACGCCGACCGGCGACATCTTCCTGTCGGAGCGGCTCTACGACGAGCTGGAGTCCTGGGTTTCGCAGCTGGTCCGCCGCACGATCCCCGCCAAGCACTGGGTGCCGCGCACCCGTCCCGACCAGCTCGCCGCGTGGATCGGCGAGTTCGTCGACAGCCAGGAGGCCCTGCGCCAGAGCGGGCGCGCCACCTCGCTCACCCTGGTCGAGGGCGGCCGGCCCCGCGGCAGCGCCCGCCGGCGGGCCGCGCTGGCCCGGTACGCCGAGCGGTTCGCGGGGCAGCTCGTGCTGGTCACGGGCGCGGCCGGCGGGATCGGCCGGGCCACCGCGCTCGCCTTCGCCGCCGCGGGCGCCCGGGTGATCGCCGCGGACCGGGACGGCGCGGGCGCGGCCGGCACGGCGCGTGCGGCCCTCGCGGCGGGGGCGCCCCACGCCTGGGCCGAGACCGTGGACGTCGGCGACGAGCAGGCCATGGAGAAGTTCGCCGCCAAGGTCGCCGCCGAGTACGGCACGGTGGACGTCCTCGTCAACAACGCCGGAGTCGGACTCTCCGGCTCCCTCCTCGACACCACGCCCGAGGAGTGGCGCCGTGTCCTGGACGTCAACCTCTGGGGCGTCATCCACGGCTGCCGCCTCTTCGGCCGCCAGATGGCCGAGCGGAACCAGGGCGGCCACATCGTCAACCTCGCCTCCGCCGCCGCCTACCTGCCCTCCAAGACGCTCACCGCGTACAGCACCTCCAAGGCCGCCGTGCTCATGCTGAGCGAGAGCCTCCGCGCCGAACTGGCCCCGCGCTCCATCGGCGTCACCGCGATCTGCCCCGGCATCGTCAACACCGGCATCACCCGCACCTCCCGCTTCGCCGGGGCGAGCAAGGAGGACGAGGCCAAGCACCAGCAGCGCGCCGCCAAGCTCTACGGCATGCGCAACTACCCGCCGGAGAAGGTCGCCGACGCGATCCTGCGCGCGGTGCTCGACAACAGCGCGGTCGTCCCGGTCACCCCGGAGGCGCGAGGCAGCCGCCTCCTCGCCCGCCTCTCCCCGAAGGGCGCCCGGGCCTTCGCGCGGCTCAATCCGCCGGTGTGAGGGGTGCGGAGGAGATGAGGCGTGCGCCAACAGGGCGTGAACGGCGCACGCCTGACGTGCTGTCATGCCGCACTCAGGGGCGAAGTTGCCCACAGCCAGGGCTAGTTATCCACAGGATCGGCCGCCAGAGCTGTGGATAACGCGGCCTCACTGTGGATCAAACCTCAATACGCCGTGGAATGACGCACAGTTGCGGGGGCTCACCCTGAACGCGCCCCTCACACGGGCTCCTTGCGCTCCGGGGTGTTCCGGCGTCCGGCTTGCCGTCCGGCCCGGTCGCCCGGGTCCGGGATGCCGGGCGGTCGCCGTGGCGCCATGATCGGTGGGTGAGCTATCCGCACCTGCCCACCACGCAAGCGGCCGTCCTGGCGGTCCGCGAGGTCGCCGGGCACTTCCACCGCACCGGGGAGGTGACCGAGGAGATCGGCGCCGACCGCGTCTCACGGCCGCCCGCGGTCACCCCGTCCCCCTGGACCGCCGGCGCGGAGGAGCTGCTTCCGCACGAGGCGTACATCGAGCTGAGCGGGACGCCCTCCGTGCAGGTGCGGCTGTACGCGGACGGCGACGCCTCGGTCTGCGTGGAGGGTGTCGACTGCCCCGACCTCGACCGGGACGTCGTCCCCGCCTTCCTCGCCTCCGTCTACGGCGGCCTGGCCCACCTGCGGCGCAGGGCCTTCCCGCCCAGCTGCCACCTGGTCGTCCCGCTCCCCTGCGGCACGGAGCACCGCGCGTACGTCTCGCCGCTCGAACTGACCGGCTGGCTGCTGAGCCGGAGGCGGTGAGGAGCCGCGCCTAGGAGAGCTGCCCGACCGCCTCGGTGGCGATCTTCTCGAAGACGGCCTGGTCGGCGGCGAAGTCCGAGCCGGCGATCGGCCAGTGCACCGCGATCTCGGTGAAGCCCAGCTCCTGATGGCGCCCGGCGAACTCCACGAAGGCGTCGACGGAGTCCAGCGGGCGGTTCCGGTCGGGGGTGAAGCCGTGGAGCAGGACCTTGCCGAGGTCGGCGACGTCCCGCCCGGCCTCCTCGCAGGCCGCCCCGAGCCGCCCGATCTGGCCGCGCAGCGCCTCGACCGACTGCTCGGGGGTCCCCGTCTCGTACAGCTTCGGGTCGCCGGTCGTCACCCAGGCCTGGCCGTGCCGTGCCGCCAGCCTGAGCCCGCGCGGGCCGGTCGCGGCGACCGCGAAGGGGAGCCGGGGCCGCTGGACGCAGCCGGGGATGTTGCGGGCCTCCTCGGCGGAGTAGAAGGTGCCGCGCTGCGAGACGGCGTCCTCGGTCAGCAGCCGGTCGAGCAGCGGCACGAACTCGGCGAAGCGGTCCGCCCGCTCCTTCGGTGTCCACGCCTCCTGGCCGAGCGCGGTGGCGTCGAAGCCGTTGCCGCCGGCCCCGATGCCGAGGGTGACCCGGCCGCCGGAGACGTCGTCCAGGGAGATCAGCTCCTTGGCGAGGGTCACCGGGTGCCGGAAGTTCGGCGAGGTGACGAGCGTCCCCAGCCGCAGCCGCTCTGTGGCGGTCGCCGCGGCCGTCAGCGTCGGGAGCGCCCCGAACCACGGGCCGTCCCGGAAGGTGCGCCACGACAGGTGGTCGTAGGTGTACGCGGTGTGAAAGCCCAGCTCCTCGGCGCGCTGCCACGTGGCGCGGCCGCCCTCGTGCCAGCGGTCGACGGGGAGGATCACGGTGCTCAGTCGCAGGCTCATGGCCCCGAGCCTACGTGGGCGGCGCCGGGGCCCTCCGGGCGCGCGGGGTGCAGGTGGCGCCGGTAGGCGGTCCGGCCGGGTTTCGGCCATCCCGGTGCTCGACCGATCGAAAGCACTCATCTGTGCGAAGGTCCGCACACGCGTGCTGGCATATGCGTCACAATCGAAGAGTGACCTCAGCGACGCCGTTGCCCCGGACCCCGGCCGCCCCGTCCGTCCCGATCCGTCTGATCGCCACGGACCTCGACGGCACACTGCTCCGCGACGACAAGACGATCTCCCCACGGACCCGTGCCGCCCTCGGCGCCGCGGAGCGGGCGGGGATCGGCGTGCTGTTCGTGACCGGCCGGCCGGCCCGGTGGATGGAAGTGGTCCGCGACCACGCCCACGCCGACGCCCTCGCCATCTGCGGGAACGGCGCCGCCGTCGTCGACCTCGCCGCCGACGACGAGAGCGGGCGCCCGCGCTTCGTCCGGGTCCGTCCGCTCCTGGAGGAGACGGCGCTCCAGGTCGTGTCCCGCCTGCGCGCCCACGCGCCCGGCACCAGCTTCGCCGTGGAACGCACCAGCGGCCTCTTCCACGAGATGAGCTACCCGCCGCTCCACCTGGACCCGGCGCAGGGCATCGCCCCCGCCGAGAAGCTGCTGGCGGAGCCCACCGGCACCGCGCCCCAGCCGGTGCTCAAGCTCCTCGCCCACCACCACGAGCTGGCCCCCGACGCCTTCCTGACCCGTGCCCGGGCGATCCTCGGCGACCTGGCCTCGGTCACCAGGTCCAGCCCCACCGCGCTGCTGGAGATCAGCGCCCACGGCGTCTCCAAGGCCAGCACCCTGGCGCTGAGCTGCGCGGAACGCGGCATCCGCCCGGAGGAGGTGGCCGCCTTCGGCGACATGCCGAACGACATCGAGATGCTGAGCTGGGCCGGTTCCTCGTACGCCATGGGCAACGCGCACCCCGATGTCCTGGCCGCCGCCACCGGCAGCACGCTCGGGAACAACGAGGACGGCGTGGCTCTCGTCATCGAGCGCCTCCTCGCGGGCGGCTGACCTCAGAGGACGACGCCCCGCTCCGCGAACCACGGACCGGGGTCGACGGCCGAGCCGTAGTACGGGGTCAGCCGGATCTCGAAGTGCAGGTGGGGGCCGGTGGAGTTCCCGGTGCTGCCGGACTGGCCGATCCAGTCGCCGGCCTGGATCCGGTCCCCCTGGTCGACGGCGGGCGCCGACAGGTGCGCGTACTGGGAGTAGTAGCCGCCGTCGTGCCGCACCACGACCTCGATGCCGTACGCGCCGCCGCAGCCGACCCGGATGACCCGGCCGGCACCGATCGCGCGGACCGGGGTCCCCGTGTCGACGGCGAAGTCCTGCCCGCTGTGCCGGTTGGCCCACCGGTCGCCCTGCCCGCCGTACCCGGCCGAGAGGGTGTAGGAGCGGACCGGCGTCATCCAGGGCCGTCCCGTACGGGCCGGGCTGCCGGCGTTGCCGAGGCGGACGGCGCCGCGGCACTTGCCGGCCGTCACCGAGGTCTCGGCCTGCCGCTCCAGCCGCTGCTGGGCGTCGCGCAGCTGGGTCTCGATCCGTGTCTTGAGCCTGCCCAGCTCGTCGGCGCGGCGGGCCAGCGTCCGGGAGACCTTGGCGGCGGTCCGCTCGCCCTCGGCCAGCCGCCGCTCGGCCCGCTGGGTACGGCCGATGGCGTTGGTGACGGCCAGATCGGCCTGGTTGGCGGCGTGCTGACTGCGGAGCAGGCCCTCGGGGTCGTCCGCCAGGAGCAGCCGCGCGGTGTACGGCAGTCCGGCCCCGGCGCGGTACTGGGCGCTGGCGATCCGCCCCAGGTCGGCGCGGTAGGTGGCGAGCACCCGGCGCTCCTCGGCGAGCCGCCGCTCCAGCCGCTGCGCCTCCCTGCGCTGGGCCCGCGAGGCGCGCAGCCCCGCCTCGTACCGCTGGGTGGCGTCGGACGCCTGCTCGTAGAGACGCGCCACCTCGGCACCGGGGTCGGGGGGCGTGTCGCCGCTCGCGTCGTGCGGGGCGAGGTACCCGAGGGCGAGCAGCGCACACAGGACCGGCAGGAAGAGGTGGCGGCGGTCTCGGGAGCTCATGCCCGGATCGTTGCCCGCCCGGCGGGGCCCGCTCTCACCGGACTCGTACGGGCGAGGGACGGCGTGCCCCGTACGGAGCAGGCGCGTACCGCTGAACAGGGTGGGCGCGGACGGGCCGGGCCGTCAGAGGGCGGCCTCCCAGACGACGGAGGTGCCGCCGCCGCCCTCGCCGATGCCGGGGCCGTACCAGCTGGAGCCCCCGAGGGACTCGGCGCGCCGCCTGAGGTTGCGCAGGCCGCTGCGGCGACCGCCGGGCGCGATGCCGACCCCGTCGTCGGCGACGGTGAGGCGGACGCCCGGCGTGCCGTCGGGCAGGGCGCGTCCGGCCTCCACGACCACCTCGATGCGGCCGGCGCCGGAGTGGCGGAAGGCGTTGGAGAGGGCTTCGCGGAGCGCGGCGACAAGGTTCTTGCCGGTGGTCTCGCCGACGAGGGTGTCGACGGGGCCGAGGAAGCGGTGGGCCGGGGTGAAGCCCAAGGGCACGGCGGCCAGGTTGATCTCGCGCAGGACGCGGGTGCGCAGCCCGGTGGGAGCGTCGGCGGGACCCTGTTGCAGGGCGAAGATCGCGGTGCGGATCTCCTGGATGGTGACGTCGAGTTCGTCCACCGCCTTGCCCAGCTTCTCCCGCACGGCGGGGGCGTCGGAGCGGCGCTGCGCCGTCTCCAGCATCATGCCGGTGGCGAAGAGGCGCTGGATCACCAGGTCGTGCAGGTCGCGGGCGATGCGGTCGCGGTCCTCCAGGACGGCGAGGCGCTCGCGGTCACGCTGGGCCTCGGCCATCCGCAGGGCCAGCGCGGCCTGGGTGGCGAACTGGGTGGCCAGGGTCCGTTCCGTCTCGGTGAAGTGCCGGGCGCCGACGGAGCGCGGGGTGACCAGTGCGCCCAGCACCCGGTCGTCGCTGACCAGGGGCAGCATCATGCTCGGCCCGAACCCGGCGCCGACCTCGGTCCGTACGCGGGGGTCGCCGGCGGCGTCGTCCACGAGGACCGGGCGGCCCGCCAGCAGTTCGCGGACGAGCGCGCTGTCGGCGGGGACGACCAGGCCCATGGCGCCGCGTGGCTCGTCCTCCCGCGAGGAGGCGGCGACCACCTCCATCCCGCCCCCCTCGGTGGGCAGCAGGACGAAACCGGCCCGGGCGTCGGCGAGGTGGCGTGCCTGTTCCGCCACGACGGTGAGCGCCTCGTCGGCGTCGCTGCCGGAGAGGAGGCTGGTGGTGACGGCGACCGAGCCGTCGATCCACCGCTCGCGCTGCTTCGACGCCTCGTGCAGCCGGGCGTTGCCGATGGCGATGCCGGCCTCGGTGGCCAGCACCCGCAGGATCTGGAGGTCCTCCTCGGTGAAGTCGGCGCCACCCTCCTTCTCCGCCAGGTAGAGGTTGCCGAAGATCTCCTCCCCGACCCGGATGGGGACGCCGAGGAAGGACCGCATCGGCGGGTGGTGGGGAGGGAATCCGCAGGAGCGCGGGTCGGTGGCGAGGTCGGCGAGGCGGAGCGGGCGCGGGTCGTGGATCAGCGCCCCGAGCAGTCCTCGGTGTCCGTCGGGGAGGTGGCCGATGGCGCGGGCCGTGGCGCCGTCGACGCCGTGGTGGACGAAGTCCGACAGGCCCTGCCCGTCCTCGGCGACGACCCCGATCGCCGCGTACCGCGCGCCGCCCAGTTCCGCGGCGGTCTCGCAGAGCTTGTCGAGCGTCTGGTGCAGCTCGGTGCCGGAGCCGACGGAGCGCATCGCCGCGAGCAGTTGCGGGATACGGACCGCCAGCTCGGCGGAGATCCCGTGCGGCCCGGGGAGGTCGGCCTCGTCCGGGAGTGAGCCGGAGCGGTTCTCGGCGGGGGGCGGCATGGAGGGAGCGTAGTTTGTCCGGTTGACGGCGAATGGCCGCGGCCCGGACGTGTCGAGTCCCGCCCGGGCCGCGCGGCTCATGCCGGCACCCCGGCCCGCCCGAGCAGCAGCGCGTCCGTGGCCCGCTCCCGCTCCCGCAGGCGCCGGAAGGGCCCGTCCTCCGCGCTCAGTTCCTCGTACGTGCCGCGCTGCACGATCCGGCCCTCGTCGAGCACGAGGATCTCGTCGACCGCTTCCAGTCCGGCGAGCCGGTGGGTGATGAGGAGGGTGGTACGCCCCCGGGTCGCGGCTAGCAGGTCGGCGGTGAGGCGGTCGGCCGTTTCCAGATCGAGGTGTTCGGCCGGCTCGTCGAGGACCAGGAGCGGGAAGCCGGCCAGGAGCGCCCGGGCCAGGGCCAGCCGCTGCCGCTGCCCGCCGGAGAGCCGTGCGCCGTGCTCCCCGACCGGGGTGTCCAGCCCCTGCGGCAGCGTCTCGGCCCACTCCAGCAGACGGGCCCGCCCCAGCACCTCGCGGAGCCGGGCCTCGGTGGCCGAACGGTCGGCGAGGAGCAGGTTCTCCCGGAGGGTGCTGTCGAAGACGTGGGCGTCCTGCGCGCAGAGTCCCACCAGCCGCCGCACGTCGTCCCCGTCGAGCCCCGGGGCGGAGGCACCGGCGAGCGTGTAGCTCCCGGTACGAGGGTCGAGGAACCTGAGCAGGAGCTGGGCCAGCGTGGTCTTGCCCGAACCGGACGGGCCCACCACGGCGATCCGGCGCCCCTCGGTCACGGTCAGGTCGATGCCGGTGAGGGCGTCGCGCGCCTGCCCGGGGTGGCGGGCGGCCACCCCGCGCAGCTCCACGGGGAACGGGCTCTCCGGCGCCGGGCCGGCCGCCTCGGGCTCGGTGACCGGGACGGGCGCGTCCAGCACCTCGTGGACCCGCTCGGCGCTGCGGCGTACCCGCTGCCGGAACTGGACGGCGAGCGGGAGCGCGGTCACCGCTTCGAAGGCGGCGAGCGGGGTCAGCACCACGACGGCGAGCGCCACCCCGTCTAGGGCGCCCGCGCTCACGCCCCGGATGCCGACGTACGCGGCGGCCACCGTGGTCAGGCCGGTGATGACCGCGGTCAGGCCGGCCCCCAGGGCGTTGGCGGCCGCGCCCCGCGCTCGGATCCGGGTCAGTTCGCGGTCCGCGTCGCCGGTCCGGGCGGTGCGGTGGGCGAGCGCGCCCGCCACCGTCAGTTCACCGGTGCCGGTCAGGACCTCGGCGACCCGGGTGGCCAGCGCTCCCCGGGCCGGTGCCAGCCGCCGTTCGGCGCGCCGGGCGAAGCCACCGCTGACCAGCGGCACTCCCACGGCCGCCGCCAGCAGGCCGATCGCGAGGACGGCCCCGGCCGCCGGCAGCAGCCAGGTCATGAAGAGGACGGAAACGGTGGAGACGAGGGCGGCCCAGCCGGCCGGGAGGAGCCACCGCAGCCAGTAGTCCTGGAGCGCGTCCACGTCGGCGACGAGACGCGAGAGCAGATCGCCCCGTCGCGTCCCGCGCAGCCCTGCGGGGGCCAGCCGCTCCAGCCGCCGGAACACCGCGACCCGGGTGTCGGCCAGCATCCGCAGGACCACGTCGTGGGAGACGAGCCGCTCGGCGTAGCGGAAGACCGCCCGCCCGATGCCGAAGGCCCGCGTCGCCGTCACCGCCATCATCAGGTAGAGCACCGGGGGCTGTTGCGAGGCGCGGGAGATCAGGTAGCCGGAGGTGGCCATGAGGCCCACCGCACTGCCGAGCGCCAGACTGCCCAGGACCAGCGAGAGGATCAGGCGTCCGCGCGCCTCGCGACCCGCCGCGCGTACCCGCACCAGGGCGGAGCCCCGTCCGGGGAGTCGTCGGTCCGCCGTGGCCTCCGCCGCCGATGTTTCACGTGAAACATCGGCCTCGGACTCCTCCGGCCGTGACGTGGTTTCACGTGAAACATCGGAGAAGAACCACTCCCACTCCTCCGGCCGCGTTTCACGTGAAACATCAACGCCCCGAGGGCCGTCCGCCACCGTCATGGAGTCGGCGGCCGAGACGACCGGGGTCCGGACGGTGGCTCCGCGCTGCGCCGGGACACCGCGCTCGTCCTCCCCGGCCGACGCCTTCGTCACCTCGTCGAGCCGCACCACCCGGTCGGCCACGGCGAGCAGCGCGGGCCGGTGCACCACCAGGAGCACCGTCCGGCCCACGGCGAGCCGGCGTACCGCCTCGACGACGGCTTCCTCGCTCGCTCCGTCGAGCGAGGCGGTGGGCTCGTCGAGGAGCAGGACCGGCCGGTCGGCGAGGAACGCCCGGGCCAGGGCGACCCGCTGGCGCTGGCCCGCGGAGAGCCCGGCACCGTCCTCCCCCAGTTCCGTCTCGGCGCCTGCGGGGAGGCCGGCGACGAACTCCCGCGCCCCTGCCTGTTCGAGAGCCCGCGCGACCTCCGCCTCACTGGCGTCTGGGCGGGCCAGCCGGACGTTCTCCGCGACGGTGCCGGCGAAGAGCTGCGGGCGCTGGGGGACCCAGGCGATGCGCTGGTGCCACAGCTCCCGGTCGACCTCCGCCAGGTCCGTCCCGCCGACGGTGACGCGGCCCTCGGCCGGGGCGACGAAGCCCAGGGCCGCCTGGAGCAGCGTGGTCTTGCCGCAGCCGCTGGGGCCGACGAGGGCGACGGTCTCCCCCGGCTCGACCGTGAAGGTGGCTTCGCGGACGGCGGGAGCGTCGCGTCCCGGGTAGCGGACGGTCACCCCTTCGAAGGCGAGGGCGCCGGCCGGCGGGGCCTGCGTCCCCGTGTGCGGCACCGGCGTCTCCAGGACAGCGAAGACCTCCTCGGCCGCGGCCAGTCCTTCCGCGGCGGCGTGGTACTGCGCCCCGACCTGGCGCAACGGCAGGTACGCCTCGGGGGCCAGGACGAGGATGACCAGTCCCGTGTACAGGTCCATGTCTCCGTGGACGAGCCGCATGCCGATGGTGACGGCCACCAGGGCCACGGAGAGCGTGGCCAGCAGTTCCAGCGCGAAGGAGGAGAGGAAGGCGATCCGCAAGGTGCGCAGCGTCGCCCTGCGGTAGTCGTGGGTGATGCGGCGGATCGACTCGGCCTGCGCCTTGGCCCGCCCGAAGATCTTGAGAGTCGGCAGTCCGGCGACCACGTCGAGGAAGTGGCCGGAGAGCCGCGACAGCAGCCCCCACTGCCGGTCCATCCGCGACTGGGTCGCCCAGCCGATGAGCGCCATGAAGAGCGGGATCAGGGGGAGGGTGACGACGATGATGGCCGCGGAGACCCAGTCCTCGGTGACGATCCGGGCGAGCACCGCGACCGGCACGACGACGGCGAGACCCAGCTGCGGCAGGTACCGGGCGAAGTAGTCGTCCAGGGCGTCCACGCCACGGGTGGCGAGGGCGATGAGGGAACCGGTCCGCCGGTCCCCGAGCCAGCCCGGGCCCAGTTGCCCGGCCCGCTCGACCAGCCGCATCCGCAGTTCGGAGGTGACGGCGGCACTGGCCCGGTGGGCCGCGAGTTCGGTCAGCCAGGAGACCAGCGCCCGGCCGAGGGCGACCGCCACCAGCAGGAGTAGCGGCGTGGTCAGGTCACCGGTGTCGAAGCGCTGCTCGAAGGAGGAGACGATCAGCTCCGCGAGGAGCATGGCCTGGGCGATGACCAGCCCGGCGCCGAGCGCGCCGAGCACCACCACCGCGGCCAGGAAGAACCTGGTGGCGCGGGCGTACCTGAGGAGTCGCGGGTCGATCGGTTTCACGTGAAACACCCTCCGGGGGCGGGCCGGGGGCCGGGCCGTACGCTCCGGCCCCCGCGTGAGCGGTCAGTGGGCTTCGGCGATGTGGTGGGTGCCGATGCGCTTGCGGAAGACCCAGTACGTCCACCCCTGGTAGAGGAGGACCACCGGCGTCGCGATCCCCGCACACCAGGTCATGATCTTCAACGTGTACGGGCTGGAGGCGGAGTTGGCCGCGGTGAGGCTCCACGCCGGGTCCAGGGTGGAGGGCATCACGTCGGGGAAGAGCGAGACGAAGAGCATCGCCACACTGGCGACGATGGTCAGGCCCGAGAGGGCGAAGGCCCACCCCTCCCTGCCCTTGGCGACGGCGCCGAGGGCGGCGAGCAGCGCCAGGACGGCGACGGCGAGCAGGACGGCCCCGGCGGTCTTGCCGTGGTCCGCCTGGGTCCAGAGCAGGAAGCCCAGGGCCGCCACGGCGGTGACGGCGCCGAGCCGCAGCGCCAGCTTGCGGGCTCGCTCCCGAATCTCCCCGACCGTCTTCAGCCCCACGAACACCGTGCCGTGGAAGGTGAAGAGGGTGAGGGTGACCACACCGCCGAGCAGGGCGTACGGGTTGAGCAGGTCGAGGACGCCGCCGATGTACTCCTTGTCGGCGTCGATCGCCACACCGTGCACGATGTTGCCGAAGGCGACCCCCCAGAGGAAGGCCGGGAGCAGGGAGCACCAGAAGATGGCGTGCTCCCAGTTGGTCTGCCAGCGGTCGTCGCTCCGCTTGGCCCGGTACTCGAAGGCGACGCCGCGGACGATGAGGCAGACCAGGATGAGCAGCAGCGGCAGGTAGAAGCCGGAGAAGAGCGTGGCGTACCAGTCGGGGAAGGCGGCGAAGGTGGCACCGCCCGCGCTGAGCAGCCACACCTCGTTGCCGTCCCAGACGGGCCCGATGGTGTTGATCAGGACCCGCTTCTCCCGCCGGTCGCGGGCCAGCAGCTTGGTGAGGACCCCGACTCCGAAGTCGAAGCCTTCCAGGAAGAAGTAGCCGGTCCACAGGACGGCGATCAGGACGAACCAGACGTCGTGGAGTTCCATACCTCAGCGCTCCCTCAGTACGAGAAGGCCATGGGCCGGTCGGCGTCGCTGGGATCGCCGCCGATCTTCTTGGGCGGGTTGAGGTCGGCCTCCGTCAGCTCGGGCGGTCCGGCCTTGACGTACTTCACGAGCAGCCTGACCTCGATGACGGCGAGGACGGCGTAGAGCAGGGTGAAGACGATCATCGAGGTGAGGACCTCGCCCTGGGAGACACCGGGGGAGACCGAGTCGGCGGTGCGCAGGACCCCGTAGACGGCCCAGGGCTGGCGGCCCGTCTCGGTGAAGATCCAGCCCCAGGAGCTGGCTATCAGCGGGAAGGCCAGCGTCCAGAGGGTGAGGCGCCAGTAGAGGCGGCTCAGCCGGGGGCTCAGCAGCTTGGTGCGGGTGAGCACGAGGTTGGGGACCTCGTCCTCGCCGGTGCGCAGGCGGTGGGGGAGGAGGAACTTCCGCCGGGTGAGCCAGAGCCCGAGCAGGCCGATCCCGAAGGAGGTCATGCCGAACCCGATCATCCAGCGGAAGCCCCAGTAGGCGACCGGGATGTTGGGCCGGTAGTCCCCGGGCCCGTACTTCTCCTGGTACTGGGCGTTCAGCTCGTTGATGCCGGGCACCCGGTCGGTGAAGTTGTTGTGGGCGAGGAAGGAGAGGAGTCCGGGCACCTCGACGGTGACCACGTTGTGGCCCTTGTCGACGTCGCCGACGGCGAAGAGGGAGAAGGGCGCCGGCTCCTCGCCCTCCCAGAGCGCCTCGGCGGCGGACATCTTCATCGGCTGCTGCTGGTACATGATCTTGCCGAGGGTGTCGCCGCTGACCGCGGTGAGCAGGCCGCCGACGGCCAGGGTGACCAGACCCAGGCGGAGCGAGAGCCGCATCGAGTCGATGTGCTTCTTCCGCATCAGGTGGTAGGCCGCGATGCCCGCCATGAAGGCGCCGCCGGTGAGGACGGCCGCCGCCATGGTGTGGAAGAACTGCGCCAGGGCGGTGTTCTGGGTCAGGACCAGCCAGAAGTCGGTCAGCTCGGCGCGGCCGGTGACCTCGTCGATCCGGTAGCCGACCGGGTGCTGCATCCAGGAGTTGGCGGCCAGGATGAAGTACGCGGAGAGGATGGTGCCGATCGACACCATCCATATGCAGGCGAGGTGGATCTTGGGCGGCAGCTTGTCCCAGCCGAAGATCCACAGACCGATGAAGGTCGACTCGAAGAAGAAGGCGATCAGCGCCTCGAACGCAAGCGGTGCGCCGAAGACGTCCCCGACGAAGCGCGAGTAGTCGGACCAGTTCATGCCGAACTGGAACTCCTGGACGATGCCGGTGACGACCCCCAGGGCGATGTTGATCAGGAAAAGCTTGCCCCAGAACTTGGTCGCCTTGAGGTACTTCTCCTTGCCTGTCCGCACCCACGCGGTCTGGAGCCCGGCGGTGAGACCGGCGAGCGAGATCGTCAGGGGGACGAAAAGGAAGTGGTAGACGGTTGTGATGCCGAACTGCCATCGCGACAGGGTTTCCGGCGCCAGTGCAAGATCCACGTCTCCTCCTTGGATCACCCGTGGACGGCGCCCACTTCGCCCACCTTGATCCCCCGCAAAGGGGTGGAAAACAGGATGCGCTTGTGAACGCGTTCACATTCACAAGCATTATGTCCTACCACCTGACAAGCGAAAGAGGCGGGGCCCCCTTTCCGGGAACCCCGCCTCCGTGCGCCCTGTCCGGCGCCGCTGTCAGCCGCTCTTGCGGAACGCCTCCGCCGCCTTCAGGAAGAGATCGTTCGCCTCGGCCTCCGCGATGGTGACCCGCACGCCCTCGCCCGCGAACGGCCGGACCACGACGCCGGCCCGCTCACAGCTCTGGGCGAACTCGGCCGTCCGCTCCCCCAGCCGCAGCCAGACGAAGTTGGCGTGCGTCTCGGGCACCGTCCACCCCTGTTCCTGGAGCGCGGCGACCACCCGCGCCCGCTCGCCGACCAGCGAGCCGACCCGGCCCAGCAGCTCGTCCTCCGCACGCAGCGAGGCCACGGCCGCGTCCTGCGCGAGCTGGCTCACGCCGAAGGGGACCGCCGTCTTCCGCAGCGCCGCCGCCACCGGCTCGTGGGCGATGGCGAAGCCCACCCGCAGACCGGCCAGGCCGTACGCCTTCGAGAACGTCCGCAGCACGGCGACGTTGGGCCGGTCGCGGTAGAGCTCGACCCCGTCCGGCACGTCGACGTCCCGGATGAACTCGCGGTACGCCTCGTCCAGCACGACCAGCACATCGCTGGGGACCTGGTCGAGGAACCGCTCCAGCTCGGCCCGGCGGACGACGGTGCCCGTGGGGTTGTTGGGGTTGCAGACGAAGATGAGCCGGGTGCGGTCGGTGATCGCCGCCGCCATCGCGTCCAGGTCGTGCACGTCACTCGGCGTCAGCGGCACCTGGACCGACTTCGCCCCGCTGATCTGCGTGATGATCGGGTACGCCTCGAACGACCGCCAGGCGTAGATCACTTCGTCGCCCGGCCCCGAGGTGGCCTGGAGCAGCTGCTGCGCCACCCCGACCGACCCGGTGCCGGTCGCCACGTGCTCCAGCGGCACCCCGAACCGCTCGGCCAGCTCGGCCGTCAGTGTGGTGCACGCCATGTCCGGGTATCGGTTGAGCTGGGCGGCCGCGGCCAGCGTGCTCTCCAGGACACCGGGGAGGGGCGGGTACGGGTTCTCGTTGGAGGACAGCTTGTAGGCCGCCGGGCCCTCGGAGGCGGAGGCGGGCTTCCCGGGCTTGTAGGTCGGGATGCCCGCCATCTCCGTACGCAACGTGGGGGTCGACTCGCTCACCGCGGTCCTCCTCGTGATCACCGGTTCGAATACTTCTCACCTTATGAGGATTGGGCTTCCCGGCGCAGGGGCTCGGCGGAGAGAACACGGTGCGTGCCACGGCGCACACCGAACGGAACCGGGCCGGGGGCGCACGCGAGACAGCCGCACGCCGGTGGCCCACGCCGTGGCGCGCATCCCTCGTGAAGGTGAGTTGAACCTCGGCCGCCCCCTCATCCGATAAGCGTGACCGTTCCTCCAGAGCATCCGATTCACCGGGCCGAAGGCGCCAAGCACCTGGCATTCCAGCGGTGTTGAGCGGAAACGACCATGCAGAAACGTCTCCGTCAACGCCTGCATATGCACCCGGGCCACCCGCCTCCATGAGCCCTACTATCGGCTCGCCATGACAGCAGCAGGGAAGCACCAGGTGAGCCGAGCGGACACGACCCGCCGGGGGAGCCGGCCAGTGCGAGCGGGCATCAGAGATGTGGCCGCCGCCGCCGGCGTCTCCATCACGACCGTGTCCGACGCCCTCAACGGCAAGGGGAGACTTCCGGATGCCACCCGCCGCCACGTCCGTGAGGTGGCGGAACGACTGGGCTACCGCCCCTCGGCGGCCGCCCGCACCCTCCGTACGGGCAAGTCGGGCCTCATCGGTCTGACCGTGACCACGTACGGGGATGAACCTTTCACCTTCACCGAGTTCGCCTACTTCGCGGAAATGGCGAGAGCCGCCACCTCCGCCGCGCTCGCCCGTGGCTACGCCCTGGTGATCCTCCCGGCGACCTCCCGGCTCAGCCCCGTCGACGTCTGGTCCAACGTGGCGCTCGACGGCACCGTGGTGGTCGACCCGGCCGACGACGACCCGGTGGTCCGCGAACTCGCCCGCCAGGGGCTCCCCGTCGTCTCCGACGGGCGCCCCGCGGGCTCCCTGCCGGTCACCGCCTGGGTCGACAACGACCACGAGGCGGCCGTCCTCGACATCCTCGACCACCTCGCCGCGGCGGGCGCCCGACGCATCGGGCTGCTCACCGGCACGACCACGGACATGTACACCCGCCTCTCCACCGCCGCCTACCTGCGGTGGTGCGCCCGGATCGGCCAGGACCCGGTGCTGGAGGCGTACCCGGCGCACGACCCGTGCGCCGGCGCCGTCGCCGCCGACCGGCTCCTGGCCCGGCCGGACCGCCCCGACGCCGTCTACGGGCTCTTCGACCCCAACGGCACCGACCTCCTCGCCGCCGCCCGCCGCTACGGGCTGCGCGTCCCCGACGACCTCCTCCTGGTCTGCTGCAGCGAGTCCACCGTCTACGCCAGCACCGAGCCGCCCGTCACCACGCTCTCCCTCAAACCCCGCCGGATCGGCACCGCCGTCGTCCAGCTCCTCATCGACGCGATCGAGGGCATCAACCAGGACCAGCCGGTGGAACAGGTGATACCGACCGAGCTGATCGTCCGGACCTCCTCGATGCGGCGCTCCCCGCGCACCACCGTCAACCCGCCCCGCTCCCCCCGACAGGGGTGAGCGACACGGAGAGCGCCGGGGAAAAGTCCTCCCAATTCGGAAGGAATCCCCGGTGAACAGAGGTCCCGTCGTTATTCACCACCCCTGGTGCACCACACAGCGCGATCCTCATTCCTATGATGGGCGGACGACACCGCGGGCCGCTGCGACCAGGCAGTCCGAACCGGTGCAGAGGCGGCGCGATGGTGGTGGAGGGGTCGATGACTCAGGGGGCCAGTCAGGGACCCACGGTGCGCACAGCGACACTGCGTGACTTCCGGGTACCCGCGTACGTCCAGCAGGCGGGGCCCCCGGCGGCCACCGCCCCGGTCGACGAAGAACCGCCGGACGGCTACACGCCGACCCAGCGGGACCTGCCGGTCATCAACCGGGGCGACACCGTGCAGGTGGCGGTGGCCCCGGAGGAGACCGCTCCGCGCCCCGCGAGCGAGGGCCTGGGGCCGCTCTACGCGGTGGGGGACGTCCACGGCTACCTCGACGAGCTGCTCGCCGCGCTCCAGGCGCAGGGGCTGGTCGACGCCGACGGCACCTGGTCGGCGGGGAATGCCCGGGTCTGGTTCCTGGGCGACTTCACCGACCGGGGCCCCGACGGCATCGGCGTGATCGAGCTGGTGATGCGCCTCTCCGCGGAGGCGGCCGCGGCCGGCGGGTACTGCAAGGCCCTGATGGGCAACCACGAACTGCTGCTGCTCGGCGCCAAGCGGTTCGGCGACACCCCGATCGACTCCGGCGCCGGCACCGCCACCTTCCAGGCCGCCTGGCTCCTCAACGGCGGGCAGAAGACCGACATGGAGCGGCTGGAGGACCACCACCTCCAGTGGATGTCCCGGCTGGACGCCATCGTCGAGGAGGACGACCACCTGCTCCTCCACTCGGACACCACGGCCTACCTGGACTACGGGGACTCGATCGAGGCGGTCAACGACACCGTCCACTCCATCCTCACCCGCAACGACGCCGACGAGTGCTGGGACCTCTTCCGCAAGTTCACCAAGCGGTTCGCCTTCCGCGACGAGGGCGCCTCGGCGGCCCGCGAACTCCTCGGCGTCTACGGCGGCCGCCGCGTCGTCCACGGCCACAGCCCCATCCCCTACCTGCTCGGCGAGTCCGGCTCCGAGGACGGCTCGCCCGACAGCGGCCCGCAGATCGACGGCCCGCACGTCTACGCCGACGGCCTCGCGGTCGCCCTCGACGGCGGCGTCACCATGGCGGGGAAGCTCCTGGTCAGCGGATTGCCCCTCGCCGACTGACCCCCGAGACCGGGCACCTCGCAGGCGGCAGGCATACGGACGGCACAGCGTACGAGACGGCGCTGTCCCCTGTCCGAATTCCGCAAAGTCCCTGTCGTGGCGGGCCGTTGCCGCTCTACCATCGGGATATCCGTAGCAGGCTCTCCTCCGTTCCCACCGACCCGCCCGCGACGTCGCGAGCGGCGATGCCCTACGGACACCTCGGGGGATGCACATGAACAGCGCTCCGCACCTGCTGAACGAGGACCGTGCCGCGTACGAGCGGCTCCTCGACGAAGCCCTGCGCACCATCACCCACGACGAAGGCCACCAGCGAGCCACCCCGCCCGGCCGGCTCCCCGTCGCCGAACTGCGGCGGCTCGCCCTGGGAGGTACCGCCGCGATCACCGCGGCGGCCGCCACCGAGTACCGGCACCTGCTCTCCCTCCGCGAGGAGCTGGGAGAGACGACCACGGCCGGAGGCGCCACCGGCGACGACCCCGCCCCCGCTCCCGGCGGCACCGGACTCACCACCGCGGTGAGCCAGATGACCGAAGCCACCGGCGCGGGCGCCCTGGCCGTCCTGGCCGTCCTCGCCCCGCTCCTCGCGGGCACGGCGGCCCTGATATTCCTCCTCGTCGGCTACGGGCTGCGGATGCTGGACCCCGCGCCCGCCCTCGCGCAGACCCTGCTCACGACGGGCTGGGTGTTCGCCGCGTTCGCGGCGGCCGCCCTGCTCGCCGCCGGCCTGGCCCTTCTGCTCACCGCCCTGCGGAACAAGGCGCTCTTCCCGGCGGCCCCGGTGCCGGCCGACCCGCTCCGCCGCGAGGTGCAGCAGGCCGCCGACGCCTGGGAGCGGGCCCTCACCGAACGAGGGATCCTGCCTTTCCTCCGCACCACGCTGGCCGAGGCGGCGGCGTCGGGCCTCGAGCCGAGGCCCGGGAAGGCAGTGGAGCCCGCCGGTTCCACGCCGGCCGACGAGGCGGACCGTATGCCTCAACTCGGCTACGGACGGCCCGGATTCAGCAGTCCTTCGGAAAGCGGCCAGGACCGGCCCGCCCCCGATTCCCGTCCCTCCTACCAGAGCCCCCAGTTCAGCAGCCCCGACTTCAGCGGTCCGGACTTCGACGGGCCGGGGCACGGGTGAACGGCAGGGCGGCCGGGGCTCGGACCCCAGCCGCCCGCTCGTCATGTTTCACGTGAAACGTCGCACGGGCTGACGTTTCACGTGAAACATCGGCTGTTGGGGTGTTTCACGTGAAACATCGTCGCGGCGGCGGGGCCCGTCAGTCCGCCAGCGGCAGGTAGACCCGGTTGCCGGACTCGGCGAACTCCTTGGACTTCTGGAGCATCCCGGCCTCGATCTCCTCCTGGGAGGCCCCGTCACCGGCCGAGTCCCCGAACCGGGTCGCGATGTCCTGGCTGATCTTCATGGAGCAGAACTTCGGCCCGCACATCGAGCAGAAGTGCGCCGTCTTCGCCGGTTCGGCCGGGAGCGTCTCGTCGTGGAACTCCCGGGCGGTGTCCGGGTCGAGCGCCAGGTTGAACTGGTCCTCCCAGCGGAACTCGAACCGCGCGTCCGAGAGCGCGTCGTCCCAGTCCTGCGCCCCCGGGTGTCCCTTGGCGAGATCCGCCGCGTGCGCCGCGATCTTGTAGGTGATCACGCCGGTCTTCACGTCGTCCCGGTTGGGCAGGCCGAGGTGCTCCTTGGGGGTGACGTAGCAGAGCATCGCCGTCCCCCACCAGCCGATCATCGCCGCGCCGATGCCCGAGGTGATGTGGTCGTAGGCGGGAGCGATGTCCGTGGTCAGCGGTCCGAGCGTGTAGAACGGCGCCTCCTCGCAGATCTCCTGCTGGAGGTCGATGTTCTCCTTGATCTTGTGCATGGGCACGTGTCCCGGGCCCTCGATCATGGTCTGCACGTGGTGCCGTTTGGCGATCGTGTTCAGCTCGCCGAGCGTCCGGAGTTCGGCGAACTGCGCCTCGTCGTTGGCGTCCGCGATGGAGCCGGGCCGCAGTCCGTCGCCGAGCGAGTAGGTGACGTCGTAGGCCGCGAGGATCTCGCAGAGTTCCTCGAAGTGCGTGTAGAGGAAGCTCTCCTGGTGGTGGGCGAGGCACCAGGCGGCCATGATCGAGCCGCCGCGCGAGACGATGCCGGTCTTGCGCCGGGCCGTCAGCGGCACGTAGGCGAGCCGGACGCCGGCGTGCACCGTCATGTAGTCGACGCCCTGCTCGGCCTGCTCGATGACGGTGTCCTTGTAGACCTCCCAGGTCAGCTCCTCGGCCTTGCCGTCGACCTTCTCCAGGGCCTGGTAGAGCGGCACGGTGCCGATCGGCACGGGGGAGTTGCGCAGGACCCACTCGCGGGTGGTGTGGATGTTCCGGCCGGTCGAGAGGTCCATGACGGTGTCGGCACCCCAGCGGGTCGCCCAGGTCATCTTCTCCACCTCCTCCTCGATCGAGGAGGTGACGGCCGAGTTGCCGATATTGGCGTTGACCTTCACCAGGAACCGCTTGCCGATGATCATCGGCTCGATCTCCGGGTGGTTGACGTTGGCCGGGAGCACGGCCCGGCCTGCCGCGATCTCGTCCCGGACGGTACGGGGGTCGAGGTTCTCCCGGATGGCCACGTACTCCATCTCCGGGGTCACCTCGCCGCGTCGCGCGTAGGCGAGTTGCGTGACCGCGCGGCCCGGGACGGCCCGGCGCGGCTTGCGGGGGCGGCCGGGGAAGACCGCGTCGAGGTTGCGGAGCCCACCGCGCGGGCTGGTGTGCTTGATCCCGTCGTCCTCGGGGCGGACGGGGCGCCCCGCGTACTCCTCGGTGTCTCCGCGAGCGGTGATCCAGTGGTCCCGCAGGGGCGTCAGACCCCGGCGGACATCGGTCTCCACCGCCGGATCGGTGTACGGGCCGGAGGTGTCGTACAGCGTGACGGCGTTTCCGTTGGTGAGGTGCACCTGGCGGACCGGCACGCGCAGATCGGGGCGGGAGCCCTCGATGTACGCCTTGTGCCAGCCGATGGACTTCCCGGCCTCGCTCTTCGGTGCGGAGGCAGGCGTGCGTGCGTCCTGTGTGGTCATGAGACCTACTCCCTACGCCGGCATTACCCGGTAACAGGTTCGGCGGTCGACGCAGCGATGTCCGCGATCCTGACCGGTGTTGACGACCGGTCGGCCGACGGAGGTCAGCGCCCTCTCAGCCCGGTGCTCCGAGCTCCCGCGTGTACAAAGGTGGCTCCACGCTAACGCCCTGTCGGCCGTGCTGAACAGTGGGCCTCGCCGACTCTTGCGATGATCGACCCGTGACCTCGACGACGCCTCCGCCTCCGCCGCCCCCGCAGCCCCCCTCGGGCGGTCCGCCGTCCGGACCCGGCGGCCACGGCGGTGAACCGCCGACGGGCGGCCACGGGCACTCCCACAGCCATGGCCCGGCCGCCCCCGTCTCCCAGCACCTGCGCAAGGTGATCGCGGCTGTCCTGATCCCCTTCGCCGCCGCTGTCGTGGTCGGGCTGCTCGTCCTGTGGCCGGGGGGCGCCCCGTCGCACGAGCGGACCGGTGTCGGCATGGACCGGCAGACGGAGCAGGGGTCGGTCACCAAGGTGGACCAGGTCGACTGCGCCGACGTGAACGTCTCCCAGCCGCCCCCCAACGGCGACACCTCCACCCCCGAGGGCCGCTCGGCGCAGGAGCAGGCGACCGGGAAGTGCGAGAAGGCGACCGTCGAGGTGACCTCCGGTCCGCACGCGGGCCGGACCTTCACCGAGATCGTCCAGCCGGACGCCTCCCGCAAGCTCCACCAGGGCCAGGGTGTGGTGGTCGCCTACGCCCCGGACGCGCCGGAGGAACTCCAGTACTCCGTCACCGACGTCGACCGGAAGTTCCCGCTGGCCCTGCTCGCCGCGATCTTCGCGGTGGCGGTGGTGCTGGTCGGCCGGATGCGGGGGCTGATGGCCCTGGTGGCCCTCGCCGCGAGCTTCGCGCTGCTCACCCTGTTCATCCTGCCGGCGATCCTCCAGGGCTCGAACCCGCTGGTGGTCGCGGTGGTGGGGGCCAGTGCCATCATGCTCATCGCCCTCTACCTCTGCCACGGGCTGACGGCGAGAACCTCGGTTGCGGTGCTCGGCACGCTCGTCTCCCTCCTGCTGATCGGCCTGCTCGGTTCGGTCTTCATCGGCTGGGCGGCGCTGACCGGCAACACCGACGACAACACCGGGCTGATCCACGGTCTCTACCCGGAGATCGACATGAGCGGCCTGCTGCTGGCGGGCGTGATCATCGGTTCCCTGGGTGTCCTGGACGACGTGACGGTCACGCAGACCTCGGCGGTGTGGGAGCTGCACCAGGCGGACCCGACGATGGGCTGGCGCAAGCTCTACCGGGCCGGTATCCGCATCGGCCGGGACCACATCGCCTCGGTGGTGAACACCCTGGTGCTGGCGTACGCGGGTGCGGCCCTGCCGCTGCTGCTGCTCTTCTCCATCGCGCAGAGCAGCGTGGGCATGGTCGCCAACAGCGAGCTGGTGGCGGAGGAGATCGTGCGGACGCTGGTGGGGTCGATCGGTCTGGTGGCCTCGGTCCCGGTGACGACGGCGCTGGCGGCACTGGTCGTGTCGGCGGACAAGGGCACGGGGGTACCCGTGGGCGGCGCTCCCGCGGCGCGGGGCGGCAGGGGGCGCCGCAGGAAGCGCTGAGACCACGGCAGGCGCCGGCGCGGGACCGGGCCGGCGCCGCCCGTTCAGCCGGCGCTCTGCTCCTCGGCGAGGATGCGGTTCAGAGCGTCGTCGAGGTGGCTGTCGAAGTCGGCGTGTGCCCGCTCGCTGCCGAGCGGGACAAGCCGGTCGGTGCGGTCGAGGAAGGCGAGCAGCGGCGCCTTGCCGACGCGGAAGAGCGCCTGCTCGGAGCCGACCTGGAGGGTGATGTGCACCTCCCTGGTGGCCGTCTGCCCCACCGGGCAGACCCGGACGTCGCCGTCGCCCGCGGCGTCCAGGACTCCCTCGACCAGCAGTTCACGCCCGAAGACCCAGGTGACCGGGGCGTCTCCGGGGAGGTGGAACGTCAGCCGCACCGCGTACGGATCGACGGTCTCGTACCGCAGCTCCACCGGGATGCGGAAGGCGAGCTCCTCGGAGACGAGGAAGCTCATCATGACCTCTGCCTATACTGACTCGCGCATGGACTACCCCGCCAGTTGCCGCCATGTGGCCGAAATCCGTCCCGGCCCTTCATGGCATCTTGCAGAACGCCATCATTGGATCACAAGGAGTGAGTTTTCAGATGCTGATAGAGAACCGGAGCCGCCGCATAATGCTGCCGACGTCCCGGTGCAGCAGCTGCGTGGTGACCCGCAGGCGTTCCGCCTGAGCGGCGGGCAGGGAGACGGCGAGGACGGCGGCGGTGGACCCGACGGTGATCGGCACCGCCGCGCAGGCCACACCGAGCGCGTACTGCTGGTACTCGACAACCGGCTGCATACGCTCGGCCGCGGCCAGCCGGCGCAGCAGACGCTGGCTGTCCGGGACCGAGTACGGGGTGAGCGGCCGGACCGGGTGCCGGGAGAGATGGTCCCGGCGGCCTTCCTCGTCGAGCTGCGACAGGAGGCACTGGCCGATGGCGTGGGCATGGGCCGTCTCGCGGAAGTCGGCCCATTCTGCGACGGCGGGATTCCCGGGCGTGTCCGCCGTCGCCACGAGGTCGACCTCGCCGTCCCGGTACAGGGCGAAGTAGACGGGTGCGCCCAGGCGTTCGTGCCAGTGGCGCAGGACGTCGTCGATGAGGTGGCGGCGGCTCTGCTGGGCGTGCGCCTCGTCGAGGCGGCCCACGGCGGGCCCCAGCACGTAGACCCCGTCGACCCGGCGCAGGTACCGCTCGTGGGTGAGGGTGCGCAGCAAGTGGTAGGCGGTGGGCAGGGCGACGCCCGCCTCCCGGGCCAACTGCTTGGCGGGAGCGCCGCCTTCGTGGAGGGCCGCCGCCTCCAGCAGCCGCAGCGCCCGCTGGACGGAGCCGATGAGTGTGGGCGCGGCATGGCCGTCGTCCTGATGTGAACCCGTGGACCAGTGATCCGGTCGGTCCGCGGGCGTGGCGTGGGCCATGGCCTGGTCACCCCCGGAAAGCATGTGCCCCGGGCGCGGCCGCCCGGAGCGGTGCGAAGGCGGGGCCTTCGCGCCGGATTCCGGACTGTAGTGCGTGGCCTGGCGGCGGGTTCGCTGCTTGGGGAGGCGTTCCCCCGGGTGGACGAACCGCCGCGCCTCTGTGCTGGCTGCTACCAGCTGCCCCGGTCCGACGAGGGGAAGAACTTCCGGACCACGTAGATGAGTCCGCCGACGAGGGCGACGAAGACCAGGATCTTGAAGAGCAGCCCGACGACGAAGCCGACGACGGAGGCGATGAGTCCGCCGAAGATGAAGAGGGCGAGGACCGGGATCGCGATCCACTTCACCCACCACGGGAGTCCGATGAATACCTCGCGTGCGCCCATGACCTGTCCCCTCTCTGCCTGTCGCGCCCGGGTGGCGCGGCCGACGGTGCGGCCCGGGCCCGGGTGGGCCCTCGCGCTGCCGTGTCGTCTTCGATGCTAGGCGGGCGGCGGGCACGACGGGCCGCCTGGACCCCCCGTCTCTCCCTGACCCTCCCCCTAGGGAACCACCGGGGTGGCGCCAGGGTTCCCGCCCGCGCCCGCGGTCAGCCCTCCGGCGGGGAGAAGACCACCATCACCCGCAGGTCCTCGCTGATGTGGTGGAACTTGTGCGGCGTCCCGGCCGGTACGTAGACGACGCTGCCGCGCGCCACCTCGGTGGTCTCCTCGCCGACCGTGATGGCCGCCCGGCCGCTGACGACGAGGTACACCTCGTCCTGCCGGTGCGGCTGCTGCGGGTCGAGCTGGCCGGCGTCGAGGGCGTACAGGCCCACGGACATGTTCCGCTCACGCAGGAACTGGAGGTAGGCGCCGTCGTTGGCGGCGCGCTCCGCCTCCAGTTCGTCGAGCCGGAAAGCCTTCATCAGCCGGTGGCCTCTCTGTTCGGTTCTCGCTGTGCGCCTTCGGTCCGGCCCGCTGCCCGACCGGCCGTGCGAGTGGACACCCGGCCGGCGCCGATCTTGTCTGTCACGATCAGACACATGACCAATTTCCTAGTCAAGACGCTGGCCAACGCGGCTGCCCTTCTGGTGGCCGTGTGGCTGCTCAACGACATCACCCTCACCGGCGACAGCACCGGCAACAAGGCGCTCACGCTCATTGTCGTCGCCCTGATCTTCGGGCTGGTCAACTTCCTGGTGAAGCCGGTGGTGAAGGTCCTGACCTTCCCGCTCTTCGTGCTCACCCTCGGCCTGATCACGCTGGTGGTCAACGCGCTGATGCTGATGTTGACCTCCTGGCTGGCGGGCCAGTTCGACCTGAGTTTCCACGTCGACGGCTTCTGGACCGCTGTCCTGGGTGGCCTGATCATTTCGGTGGTCTCCTGGGCTCTCAACGTGGCCCTGCCCGACCGCAAGGACTGACGGCTCCGACACGCTCCGCCTGGGCGGGCCGTCCGCACGGCCCGCCCGCCGAGCCCGTCTGTCCAGGTCGTGGACGTGTGGTGCGGCGCCGGGAGAGCGTGTCCGATGCTGTGGGCGGGCGGCCCTCCGGTCGGCGTCCGCCCGACGGGGGCCCGAACAACGCGAGAAAGGCGGCCACGATGACGGGCGAAGGTACGAGGGCGGTACGGGCGGGGCTGCCCGAAGCGGTCAAGAACGAGCCAACGCTTCCCGGGCCGGTCTTCGCCGCCCACTTCCACCTGCCCGGTGACGTGAGCGGGCCCTACTCCTACGGCCGGGACTCCAACCCGACCTGGACCCATCTGGAACGCGCCATCGCCGAGCTGGAGGCACCGGGCGAGGAGGCGCACACGCTGGTCTTCGCCTCCGGCATGGCGGCCATCGCGGCCGTGCTCTTCTCCCAAGTCGGCACCGGCGACGTGGTGGTCCTGCCGGACGACGGCTACCAGGCCCTGCCGCTGGTCCGCGAGCAGCTGACCGCCTTCGGTGTGGAGGTCCGCACCGCCCCGACCGGCGGTGACGCCCAGCTGGAGGTCCTGGAGGGCGCCAAGCTGCTGTGGATCGAGACGCCGTCCAACCCCGGCCTCGACGTGTGCGACATCCGCCGTCTCGTGGAGGCCGCCCACGCCCAGGGGACGCTCGTCGCGGTGGACAACACCCTGGCGACCCCGCTCGGCCAGCGGCCGCTGGAGCTGGGCGCGGACTTCGCGGTGGCCTCGGACACCAAGGGCATGACCGGCCACGGCGACATCCTGCTCGGCCACGTGACCTGCCGCGACGCGGAACTGGCCGCCGGTGTCCAGCGCTGGAGGAAGATCGTGGGCGCGATCCCGGGCCCGATGGAGGCGTGGCTCGCCCACCGCTCCCTCGCCACGCTGCAGCTCCGCGTCGAGCGCCAGACCGCCAACGCCCTGGCGCTGGCCGAGGCACTCCGGGCCCGTGCCGACGTGACGGGGCTGCGCTACCCCGGGCTGCCCGACGACCCCTCGCACGCGGTTGCCGCCCGGCAGATGCGGCGCTTCGGCTCGGTCGTCTCCTTCGATCTCGGGACGAGGGAGCGGGCGGAACGATTCCTGGCCGCACTGCGGCTGGTCGAGGACGCGACCAGCTTCGGCAGCGTGCGCTCGACAGCCGAGCGGCGGGGCCGCTGGGGCGGGGACGCCGTCGGCGAGGGGTTCGTCCGCTTCTCCGTCGGGGCGGAGGACGCCGAGGATCTTCTCGCGGACGTGACGTGCGCCCTCGACCTCTCCCTCGACGGCGCCTGAGCCGGCCGCACGGGAACCCCCGCACACGGACGGCCCGAGCCTCCCCCCTCGTGGCTCGGGCCGCCCCGGCTCCGGTACTGAAGAGCCGTCCTGTCCAGGCTAGTTGACCCTGCGTCAGTGTCCAATCACTGTGGCAGCAGCGACCTATCGACATATTTATCGTTGAACTGCGAGTGACGGCCTGCGACGAAGGGGTTGAGGGCGTGGATCTGGCGCTGCTGCGTACGTTCGTCACGGTCCACCGAGCCGGGTCCTTCACCCGCGCCGCCGCCCTGCTCGGCCTCTCCCAGCCGGCGGTCACCTCGCAGATACGCACCCTGGAGCGGCAGCTCGGCCGCCCGCTCTTCCTCCGCAAGGCCCGTGGCGTGACGCCCACCTCGGTCGGCGACGAGCTGGCCCACCGGGCGGCGCCCCATCTGGACGCCCTGGTGGAGATCGCCGAGGGCGGCCTGGAGGTGGAGGCGCCGCTACGCACCCTGCACCTGGCGGGCCCGCCCGAGTTCATGGCGGAACGCGTCCTGCCGGCTCTCGTCGGGATGACGGGGGCGGAGGGGCCGGCGGTCCGGCTCCGCACCTCCTTCGGCTCCACGGACGACGTCCTCGAAGGGCTCGCCGCCGGGCACCACGATCTGGCGGTCGCCACCCGCCGCCCGCGCGGCACCCTGCTCAGCGCCGGAACGCTCTGCGACGAGGAGCACCTCCTGGTGGCGGGAGCGCGCTGGGCCGGGCGGTTCGCCCCCGGTGCCGTCCGGCGTGGCGGGGCCGAGGCGCTCGCCAAGGTGCCCGTCGTCGACGTGCACGAGTCCCTCCCCTTCGCCCGGCGCTACTGGACCACCGTCTTCGACGCGCCTCCTCCCGAGCACGCCGCTCTGGTCGCCCCCGACCTGCGGGCCGTCCTGTCGTGCGTCGTCTCGGGCGCAGGACTGGCCGTCCTGCCCCGGTACCTCTGCGAGGACGCCCTGCTCCGGGGCGAGCTGGTCACGCTGCTGGAGCCGCCCGTCCCTCCCCTGCGGACCTACTTCGTCGCCGTACGGGCCGGTACGCAGGCTCTGCCGCACATCGCGACGGCCCACGAGTGGCTGCTGCGGGCCGCCGTCGCCTGGGGGTGAGCCCCGGCGATGTTTCACGTGGAACATGTGGGGCCAGATTTCCCCCATGACCGTTCGCTCCGTGGTCAAGCGCACCGCCCGCGCCGTCCTGCTCGACGGCGACCAGCTCGTCCTGATCAAGCGCACCAAGCCCGGCGTCGATCCGTACTGGGTGACTCCGGGCGGCGGGGTCGAGCCTGAGGACAGCAGTGTCGTCGCCGCGCTCCACCGCGAGGTCCTGGAGGAGCTGGGTGCCAAGATCACTGATGTCGTCCCCTGCTTCGTCGACACCGTCGAGCACATCGGTGAGGACGCCGAGACCACCGGCGTGAAGGTGCAGCACTTCTTCGTCTGCCGCCTCGGCTCCATGGACCCGGCTCTGCGCCACGGCCCGGAGATCGAGGAACCCTGCGGGGAGTACGAGATCGTGCGCATCCCGTTCACCCGCCTCGGCATCGCCTCGGTCCACATGGTCCCGCTGTCGCTGCGGCACTATCTGGACGGCAACATCGAGGGCGTCCAGGCGCTGCTCGCCCCTGATCTCGGCTGAGCGGGAGCGGGCCCGCCCCCGATGTTTCACGTGAAACACAGCACATCCCGGCCGGGCCCGAGGGACGAGGCTCTGTGCACTTCGCCCATGAGCTGCACAGATGTCTGCCGGGCGCCGCGCTCCGGCCGCCTTGGAAGTGCTCGCTCCACGGCTGAAAAGACGGTGGACGGGAGGGACCCCCGTCGGTCAACCTGGGCCGCGTGTCGACACCTGCGCTCTCCGCTCTACCGGTTCGCCCGCTCACCCTCCGGGACCTCCCGGCCTGCACGAGCCTCGCGTACGACCGGGGGTGGTCCCCGGAGGAGCACAAGTGGCGGCTGCTGCTCGCGGCCGGGCACGGGGTCGGCGTGGACGCCCCGGACGGACGCGGGCTGCTGGGCGCCTGCACCCTGACCGACTTCGGTCCGCACGAGGCCCCCGCGTTCACCGCGATCGGCATGATGCTGATCGCCGACCGGTACGCGGGGCGGGGCTTCGGCCGCCGCCTCCTGGAGCACGTGGTCCAGTACAGCGAACGGGTGCCGCTCACCCTCTACGCCTCCGGGAGCCTGCTCCCGCTCGCCCGGAAGCTCGGCTTCACCTCGGTCGGCCGCGCGGCCACTGCCACCGGCCGCCTCACCGGTCCGACCGCCCTCCCGGAGAGGCCCCGGCTCACCCTCTCTCCCGCGCGGGCAGGGGACCTCCCCCGCATCCTCCAGCTCGATGCCGAGGTGTTCGGGACCGACCGCACACCCCTGATCGCCCGGCTCCCGGCCTTCGCCGACCGCTTCCTGGTGGCAGAGGAGGACGGGGAGCTGACGGGCTTCGCGGCACGCTGGCCGAACACCGCGACCGAGGTCGTCGGCCCGCTCGTCGCCCGCGACACCCGCACCGCCCAGGCCCTGATCACGGGCCTGGCCGAGGGAAGCACCCGTCCGCTCCGGGTGGATGTCGACGTCCGGCACACCGCACTGCTGGAGTGGCTGGGCGAGCGCGGGATGCCGGTGGTCGCCACCAGCGAGCTGATGACCCGTGCCCTGCCCGGCCTGCCCGGAGACTGGACCAGGCGGTTCGCCCCCCTCACCGTGGCCGCGGCCTGAGAGCGCCCGGCCGGCGCGGGAACATGTGATTGCAGGCGCGCGTTACATGCATGCGCGTGCTATTGCGCGCATGTCTTAAGCTGGACGGCACCCGGGCTTTCGGCGCCCGCCGGGATGAGCCGAGGGGCACCGACAAGGAGGAGCGAGGACCCATGACCGCCACGGACCCCGCACTGACCGCACTCGCCCAGAGCTGGTGCGCACTGTCCCTGCTGCACGGCCGCATCGAGACGCACGTGGAGCGGGCCCTCCAGTCCGGGCACGGGCTCAGCACCCGCGAGTATTCCCTGCTGGACGTCCTCAGCCGGCAGCACGACGGCGAGGGCGGCCACCTGCAGATGAAGCAGGTCGCCGACGCCGTCGTCCTCAGCCAGAGCGCCACCACACGCCTGGTGAGCCGCCTGGAGGACCGCGGCCTCCTCTCCCGCTACCTCTGCCCCACCGACCGGCGCGGCATCTACACCGACGTCACCCCGGCCGGAAGGGCCCTCCTCGACGAGGCCCGCCCCACCAACGACACCGCCCTGCGGGAAGCCCTTGACACCGCGGCCCAGAACCCCGAGCTCGCCCCGCTCGTCCAGGCCGTGGAGACCTTGCGCACCCCCGCCTGACTCCTCCTCGCCCTCCGGTGGCCGCTGCCGGCCCGTCTACTGTGCCGCTCATGGACCATTCCCAAGACGCACCCCAGCAGGACAGCTCCCAGGGTTCCTCCGGCGACACGCTCCTGATACGCCGCGCGGAGGCCTCCGACGTGGCCGCCATCGTCGCCATGCTCGCCGACGACCCCCTCGGAGCCACCCGGGAGTCCCCGGACGACCTCACCCCGTACCTGGCCGCGCACACCCGGCTGGCGGCCGACCCGAACCAGCATCTCGTCGTCGCCGAGCGGGCCGGGAAGGTCGTCGGCACGCTTCAGCTGACCCTCATCCCGGGCCTCTCCCGTCGGGCCGCCACCCGGTCCCTGATCGAAGGGGTGCGCGTCCATGCGGACGAGCGGGGCAGCGGGCTCGGCACCCTGCTCATCGAGTGGGCCGTCGAGACCTCGCGCGCCGAGGGGTGCCGGCTCGTCCAGCTCACCTCCGACGCCACCCGCGAGGACGCCCACCGCTTCTACGAGCGCCTGGGCTTCGTCGCCTCCCACGTGGGGTTCAAGCTCCAGCTCTGAGCCGGGCCGCTTCCTCTCGGCGGGTGCCCCAACAGGCCGCTGACGAACGATGTTTCACGTGAAACACCACATGGGTCATGTTTCACGTGAAACATCATGGATCACCCCGCGCGGAGCGGGTGTTTCACGTGAAACATCCCGATCGAGGCAGCTCGGTCAGCCCAACTCCCCAGTCGCGCGCCAGCCCTTGGCGTCCACGCCACCAGGTACCACCGAATCCGGCGCATAGGGCTCCCGCGTGAAGACGAACGAGCCCAAGTCCAGGTGCGTCACCGCGCCTTCGGCATCTCGCACTGGGCGCAGGGTCTCCCCCAGGAAGTATCCGTCCAGGCCCCGCCATGTCCCGTCACCGGCGGGAACGAAGCGTGCGGCCCGTCCGACTCCCTTCAGCGGTCGCAGCTCCACCACGCCGTCCGCCCCGTAGTGCAGCCCGTAGGGCGTCACACCCCAGTACCAGGCACCCGCCAACTCCAGCACCCGCGGGTCGGCTTCGGACATCGGGCGCCAGAGCCGGGGCATCGACGGCTCGGCCTCGGCCACGATGCCGATGAGCTCGGCGGCAAGGCTGCCGATGAGGGGACCGGAGGTGGTGTTGGCGAGGACCACGGCGGCCAGGCCCTCGTCCTCACGGGTCAGCAGGGCCGCGAGGTACCCGGGCAGCGAGCCCATGTGGCCGGTGAGCGTGATCCCGCCGCCGACGCTCAGCACCTGTGTCCCGAGTCCGTAGGCGCTCTCCTGCGCCCCGGGCAGGCTCGGGGCGGCGGGCGTCCGCATCTCGCGCACCGACGCGGCACCGAGCACCGCGTCGTCGCCCTGGACCAGGAAGGCGGCGAAGCGGAGCAGGTCACGGGTGGTCGACCAGAGCTGGCCGGCCGGCGCCATCCGGCCCAGATCGTGGGCGGGCTCCGGGAGGAGGGTGTCGGCCCAGGGGTGCACCGCCCAGCCCTGCGCGTAGGGAGCCTGCGGCGCGTAGCTGGTGCGGGTCAGCCCCAGCGGCTCCAGCACCTCGGCGCGCAGCACCTTCTCCCACGGCTCGCCCCGTACTTCCTCGACCAGCGCACCGAGCAGGGTGTAGCCGGGGTTGGAGTAGTGGTGGACCCGGCCGACGGGGTGGCGGTGCGGTTCCTCGCCGAGCACGTCGGCCAACTCGGGACGCAGTGTGCCGGGGCTCCGCTCCCACCACTCGCCCGGGGCCTCGGCGGCGAGGCCACCCGTGTGGGAGAGCAGGTCCGCGACGGTGGCCCGGCCCGCGCCCGTACCGGGCAGATGCTTCTCCAGCGGGTCGGTCAGCTCCAGGAGCCCCTCGTCGCGGAGCCGCATGACCAGAACAGCCGTGAAGGTCTTGCTGATCGACCCGATCCGGTACTGGGTGTCGCCGTCGGCCTCGACCCCCTCCAGCGCCGAGAGGGCGCCTTCCCAGATCACCTCGCCGTCCCGCGCCACACCGGCCACCAGCGACGGCACCCGGGACTCGCTCTGCGCCCTGGCGAGGCGGTGGCGCAGCGCCCGGCGGGTGGCGGGCAGGAGGCTGAGGTCTTCCGGGGTCTCATGAGTCGTCATGGCCCCACTCCACTCGTTCGGTCCGGCGAGGTCCAGCCCTTTTCCCGGTCACGTCAGGTGTGGCTCACCCGGCCGACGCGGGGCCCCGGCCGCCGTAGAGGACCTGGTCAGCTCCGCATCGCCCGCACCGCTCCGCTTCACGGAGGCCGACCGCGTCGAGCAGGCGCCGGGACGGGATGTCGGCGACCCGGGTCATCGCGATCACCTCGGCCTGCGGGCCCCGCCCGTTCCGGTGCCGGTCGGGCACCGCGCTCACCGCATCCCGTGCCGGCCCCCGCCCGGAGCGTCCTCCGCGCCCCGCTCCGGTGGGGCCGTCATGCCTTGAGGCTCTCCCGCAGCGCGGTGATGAGCCGGTTGGCGCGGTCGTCGCCGTGGCCGATCATCCGGTTGGCCACGTAGGCGAAGCCGACGCCGAACTCGTCGTCGCCGAAGGCGAACTGGCCGCCGGCGCCGTCGTTGCCGAAGCTGCGGGCGCCCAGCATGGGGCGGGGCCGCTCGGAGTCGAGGAGGAAGCCGGAGCCCCAGCGCTGACCGAGGTCGTACCCCTGCCAGGTGGGTCCTGCCGACACCTCGCGCACCGCGTCGGTCAGGGTCTCCTCGGAGAGCAGGCGCGGTCCGCCGTCGAGGCCCGTCACGGCGGCGCCGTACAGCGCGGCGAGTCCGCTCGCGGAGGCGACCGCGCCGGCGCCGGGGAGTTCGGTGCCGAGCAGTTCGGGGTCGTTGAAGCCGTGCGGCTCGTCCAGGCCGGGGAAGACCAGCGCGCCGTTCATCGTGACCATGCGCATCAGCAGCGACTGCGGATCGCCGGCGGGGCGCCCCTCGGCCTCGACCAGGCGCGCCAACTGCCCCCTCTCGGCGGCGGGCAGGCCGATCCAGGCGCGCAGCCCGAGCGGCTCGCCGATCGCCTCGCGGAAGAACCGGCCGGGGGTGAGCCCGGTGATCCGGCGGACGACCTCACCGACCAGGAAGCCGAAGACGTGCCCGTGTCCTGACGAGGCCCTTGGCGCAGGAGAAGACGGGGACCACCGCCTCCTGGTCCCAGAGGCGGCCGGACCGCTCGTCGCCGACCCCGCCCCAGAGCTACACCACCGGGCGGCCGCCCACCCGGACCGAGACCGCCGTGCCCAGTTCCCCGTCTCTTCGGCGGGCCGGGCCCCGGCGCGCCTCACCACTGCCGGTTGACGGTCGCCTTCGGGCCGGTCACCAGGGTGGCCGGCGGAACGTCCTCGGCCACCACCGCGCCCGCGGCGATCACGGCGTCCCGGCCGATGCTGACGCCGGGCAGGATCGTGGCTCCGGCCCCGATCCACACGTTCTCCGCCACGTCGATGGGGCCGCCGCTCAGCCACTCCCGCCGCGCCCCGGGGTCGACCGGATGCCCGAGGGTGATGAAGGTGGCCTTCGGGCCGACCATCACGCGCTCGCCGAGCCGGATGCCCGCGTAATCCAGGAAGGTGCAGTTCTGGTTGATGAACACCCGCTCGGCCAGCTCCAGGTGGAGGCCGTGGTCGGTGTAGAAGGGCGGGTAGATCGTGGTCCTGGCGGGCAGCGGCCGGCCGAGGATCCGCTCGAACAGCTCGGCCTTGCCCGCCTCGTCCTCGAACGGCAGGACGTTCAGCCGCGAGGTCAATTCGGTGGCCCGCAGGACCCGCTCGGACATCGCCCGGAACTCGTCACTGTGGATGCGCATGAGGCGGTCGTCGGCCATGGCCGAGCAGGCTACCAGCGCGCGGCCCGGCGATCTCGCGTGAACTGGGCGTTCCCGGTGGCCTCCCGGGCTTGTCGCCCGCGATTGTCCCCGGCCCGTGGTATGCCCGTCGGGGCGAGGCCGGTCGGCCCGCCCGGGTCGACGGAAGGCTGGGCCGTGCGAAAACTGATCTACGGCATGAACCTGTCCCTGGACGGCTACATCGCCGCGCCCGGCGACGACATCGGCTGGAGCGGACCACCCAGCGACGAGCTGTTCCAGTGGTGGCTCGACCAGGAGCAGGCGAGCGGCCTGACGCTGTACGGCCGTAAGCTGTGGGAGACGATGAGCGCCTACTGGCCCACCGGCGACCAGCAGCCCGACGCCACCCCGGCGGAGATCGCCTTCGCGCGGAACTGGCGGTCCACACCGAAGGTGGTCTTCTCCTCGACGCTCGACGGCCCGCTCGACTGGAACACCCGCCTGGTCACCGGCGACGCGCTCGCCGAGATCACCCGCCTCAAGGCCGGGGACGGCGCCCCGCTGCAGATCGGCGGGGCGACGCTGGCCGCGGCGGCCATGCGCGCCGGGCTGATCGACGAGTACGCGATCGCCACCCACCCGGTGCTGGTCGGCGGCGGCACACCGTTCTTCGGCCCGCTGGACGGCTGGGTGAACCTCAACCTGCTGGAGACCCGGACGTTTCCCGGCGGCACCGTCCTGACCAGGTACGAGACGAGGCGCTGAGCGACGGCGCCCACGCGGCTGTAGGTTCTCACCTTCGGTGTCAGGGGCCGCCGCTATGACCAGGGCGTTTCCCTTCAGTCTCACGACACGTCGGCCAGCTGCTGTCTCAGAGCGATGTCGTTTCCTCAGACTGTCCGTCAGCCATCCGTACCATCCACTCGCGCACGGTCACCGCGTGCTCGATGCGGTTGACGATGCCCTTCTTGGATGCCGTGTCCAGAGCCTTCGAGATCTTGTCGAAGTGTCGGGAAGGACATCGAGCAGACCCCAGATCTGTTCGCCGGTTCCGACAGTCAGGTCCCAGTAGTTCTCGCCGAAAAAGCAACGCTAAGGGCTGTCCCGTAACTGCTGGTCACAGATGAGATGATCTTGGCGTGGCTGGTGTGATCACTGCGTCGGAGCCGTCCTGGATTGCCCCGTTCAGCGGGCTGAGCCCGAGGCAGTTCGGGAAGCTGGTGACGGTGCTGCGTCGCGAGGGTGCGGACGCGGTCCGCAAGGGCCGGCCGTGGAGCCTGCCCCTGGAGGACCGGGCACTGCTGGTCGCGGCGTACTGGCGCACAAACCTGACCATGCGGCAGCTCGCCCCGCTGTTCGGGGTGTCGAAGTCGGCGGCGGACCGGATCATCGACCACCTCGGACCGATGCTCGCGCTCCAGCCCCGCAAGCGATTCGCCAAGGACACCGTGCTCATCGTGGACGGCACACTGGTCCCCACCCGGGATCACACCATCGCCGAGCGGTCGAAGAACTACCGGTACTCCACCAACCACCAGGTCGTCATCGATGCCGACACCCGCCTGGTCGTGGTGGTCGGACGGCCGCTCGCCGGCAACCGCAACGACTGCAAGGCATGGGAGGAATCCGGCGCAAAGGCCGCCGTCGGCAAGACCCTCACGATCGCCGACGGCGGCTACCCGGGCACCGGACTCGTCATCCCGCACCGCCGAGAGCGCGGACAGGCCGGACTCCCGGACTGGAAAGAGGAACACAACAAGTCCCACAAGCAGGTCCGAGCCCGCGTCGAGCACGTCTTCGCCCGCATGAAGACCTGGAAGATCCTCCGCGACTGCCGCCTGAAGGGCGACGGCGTCCATCACGCCATGCTTGGCATCGCCCGCATGCACAACCTCGCCCTCACCGGATAAACCGGCGGTCCGCACAACGGCCTCCCCCATACCCGAGGCGACCCGAAGATCATTTGCGGGACAACCCTTAGGGGTCGGGGGGCGCCAATATGCTTCTCGTGAGCTTCAAACGCGGCCGAAGATCGGCCCGGGTCAAGCGGGTAGGAGTGTCAGGCATGGCCGACACGAAGGTCGTTTTCGTTGCGTTCGCGATCGAGGACGAGCGGCAGAGGGACTTCCTCAAGGGGCAGTCTCTCAGCCCGCGCGCGCCGTACGAGTTCATCGACATGTCAGTCAAGGAGGCCTACGAGTCCGGGTGGAAGGACAAGGTCCGCACCCGCATCCGGCGCTCCGACGGCGTGATCGTGCTGGTGAGCAAGAATTCGCTGACGTCGGAGGGGCAGGAGTGGGAGATCAAGTGCGCGAAGGAGGAGGGCAAGAAGATCCGTGGGATCTGGGCGTACAGCGATGACCGGACGCAGCTCGCTGGCGTAACGACTGTCGTCTGGAGCGACGCGAACATCTCCTCGTTCATCGACTCGCTCTGAGGCAGACACTATGCGTAAAGCCCTTATCGTTGGAATCGACTACTACGAGAAAATCGGCTCGCTCAATGGCGCGGTCAACGACGCGCACAGCGTCAAGACGACCTTGGAGCGCAACGCCGACGGCACTCGCAATTTCGCGCAACCGAACCTCATGACGAGCACCGGCCCGGGATCGGACGTCACTCGCGCCGAACTGCGCGAAGCGATCGAGCAGCTCTTCCAGGATGATGCAGAGGTCGCGCTGCTGTACTTCTCGGGCCACGGTTACATCGACGGCATCGGCGGGTACCTCTGCGCGAGCGACTTCGCCACCGAGCACGATGGCCTCTCGCTCGCGGACATCATGGGCTACGCCAACAAGTCGCCGGCAAAGAACAAGGTGATCATCCTCGACAGCTGCCACAGCGGCGCAGCTGGCGGCAGCGCGGTCTCCGCCAAGGTCGCAGAGATCTCCGAGGGCGTCACGATCCTGACCGCGTCGGCGGCGAATCAGTACGCGGTCGAGACGGGCGGCTCAGGCGTCTTCACAAGCCTGTTCGTAGACGCCCTCAGCGGGTCCGCGGCCAACCTCGTCGGCGAGGTCACGCCGGGCAGTGTCTACGCTCACGTGGACCAGTCTCTCGGCCCGTGGTCGCAACGGCCGATCTTCAAGACGAACGTCAAGGAGTTCGTGTCGCTGCGCAAGGCCGACGCCCCGATCGAGCTTGAGAAGCTGCAGAAGCTTGTCGAGCTGTTCCAGGAGCCCACCACCCTGCTCCAACTGGATCCCAGCTACGAGCCCGAGCGCACCGGAGCCGAGGACCCCTCGGTCCCGGCGCCGGACCCGGTCAAGAATGCGGACTTCGCAGTCCTGCAGGCGCTGGTGCGCGTCAACCTGGTGCGCCCGGTGAGCGCACCACACATGTGGCACGCGGCCATGAACTCCAAGACGTGCGAGCTAACCGTGCTAGGCCAGCACTACTGGTCCCTCGTGAAGCAGGGCTTGATCTGATGTCGGATGCAGCAGGAATCCGCGAAACGCTCGAAAACCATCGGGCAATCGACAGGCTCGCGGCGATCGAGCACGACCGTTGGGCCCATTGGCAGCAGTATCTGCACGACCAGTGCGAGCGTCGCGACGACGGCTCATTGGTGATCCCCGCAGAACTCGTCTCCCGATGGGAGGAGCAGATCCGCACCCCCTACGAGGAACTAGCTCCCGAGGTACAGGAGAGCGATCGCGAGCAGGTGCAGCGTTACCTGCCCACAGTCATCGAGATCCTGGCCGACTGAAATGGCCCCCGACAGAGACCCCCCAGGCATCCGACTGGGGGGTCGTCCTGTGTGTCTGGACGTCTCTTTGAGCTCGACCTCGTGCAGACGGCCGCCACGATCTTCTTGCCGAAGGAGGTCAGTTTCATGGCCCGGCCACGTACCGCACGTTCCAACAGCGTCTTTCCGAGGTCACGTTCAAGGCGATTGATCTGAATCGCCAGGGCCGACGGGTGGATACTCAGGGCCTTGGCCGCCTCACCGATCGTGGGGTAGGACGACGCGGCCGCGAAGCGTTCAAGCCGCTGCCAGGCGAAGGCACTGGTGAGGGCCTTGCGCAGAATTGCGGGGGTGCTGGCCGTCTGTGAGGTCACCTTCAGGGCGGTCTTGTGGCTTCCGCCACCGCGGGGGCGAAGAGGGATCTTGTGGATGTGTGCCCAGCGGGCCATGTTCGCCGTGCTCGTGCCGGACTCGCGGGCGAGGTCGGGAAGGGTGCGCCGACGGACGACGTATTGCTCGATGAGCCAGGCCCGTTCGATGGTTCCGCGACGCTTGTAGTCCTGGGGTCCGTCACGGATCGGGATGCCGTACTCGCGGGCGAGGGCTGACAGAGTCTGGCGGGAGAAGCCGGTGTGTTCGGCGATCTGCTGAAGCGAGCGGTGTTCATCCAGGTAGAGGCTGGTGAAGGTCTCCTTTGGCACTTCCTGACGTGCTTTGAAACGGATGAGGCCGGTCGCCTTGGCGATGGTCTCGGTCGGTGGGAGAGCCGGGGCGGGTTGTTCATCCAGCACGAGGCGGATGACCTCGATGTTGGTGCCGAAGGTCTCGGCCGCATGCCGGACCGGGCTCTTGTGCTGCCGGACGAACTGGTGCAACTGAGCAACATCGATGCCGTCCAGATCAGGCCCCGGCAGAGCGAGTCCGCTCAGCAAGGTCAGGGGCGGCTGCCAGGTCACCGGCTCGTCGTGAATGCCGTGGGCGGCGAGGAAGGTGCAGGCTTCCTCAGCCAACGCCTGGGCCAAATCTGGGGTTTGGATGGTGGCGAAGCGGGCTACCTCGGCCCTGAACCGTGCCTCGTTGATGCTGGAGTGATCGGGGGCGGATTCGGCGGGAAGGCCACTGATTCGCTGGAACAGCTGGCAGCGGACGACGCGCTCGCGGAGTCCGTTTCCGGGCAGTGCGCCGGTGCGGCGGCAGATGTCCCGCCAATGCTCGTGCGGCAGCAACTGGGAGTAGTCCAGACGGCGCCGCCGCTGGTAGTCGATGGGAACCTCGGTCGCATCGAGGTGATCAGAGAGTCGGACCAGTGCGGCAACGGAGTCCGACCAATGCGGCTGGTCGTCCAGCACCTGCAGGATGCGGGAAATACCGATGCTGTCGGTGACCGAACCGAGATGCTCAGCGGCATCCTCCAGGGGGACCTTGCTGTCGACGACCAGCAGGGCGGCGGCCAGGACCGGAGCAAGGATGCGGGGGTAGACGCCGTCGGGAGGGGTGAGCCGAACCGTCCAGGAAAGCCAGAACATGCTGGGGACCTTCCGTGCCCGATCTTCGATCTCCCGGACCGTCCTCTTCGGGAACCGGGGCATGGCGGTGGGGGTGCGGTAGCGGAGATGTTCGCTGGGTCGGAGCGAGGGGGCGAGGGCGGCAAGATTCACCGCGCCCAGGACGGGACTCAGGCCACGTCCCCAGCTGTCGATGCTGGTGGCGCTGATTTGCCATAGCTCCTCACGCATCGCCTCCAGCAGGCCACGCAACTCGGTCCCCGCCCGGTGGACATCGGATTGTCCGAGAACACGCAGGGCGATACTCACCGCGACGGCCGTACTCACGGCCCGCGGTGGGGCCATGAAGCCGGGCCGTTCGACCGCTCTCCGGGCGAGTGGGGAGCCGGGATCGACGGTGTAGTAGTCCTCGGCGATGTCCACCGGCACCAGGCTCCTGATGTCGTGTGCGGGCAGGTCTGCCAACACCCGCCCGCCGATCGCCCGGACGTCGGCCAATGCTGCCCGGGACGGCTGCGGGTCGAGTGCGTAGGCACCGAAGTCTGCGATGTCCGTCTCAATGACGTTCATCAGCACCTCCTGGGCCCCGAGCACGGGATGCGCCGCAGGCAGTCGGAGCGTACGGGTCTGCGAAAGATCGAAGTCGCAGCCACCGGATACGAGGCTGTCGTCATTGGCAGCTGGATTGCCGCAGACTCCCAAGTGGGGAACCACCCGCCCGGAACGAGGCCGCTGACGAGGGATGCGCTCGCACTGAGGGCAGCAGTCCGCCAGTAGACAGCCATGGCGAGGACAGGCGAAAGCCCAGCCCAGACGCCAGAACAACTGCCAGCGGCCGCCGGTCTCCCGCAGGCAGTCGGGGCAGAACCGCGAGCCACTGCCGCGGCCCCAGAGGACACGGCGGTTCACGTACCGCCGCTCGAAATTGATACTCACGGCCCGTGAGTCGAAGTGGGCGAGCGTCATGCCCCTGACGATCTGCTCGTCCAGCCCGCTCGCGCGCGTGATGGCCGCGATCTGATGCTCGTTGAGCAGAATCGTCCAGTCCGAAGGAATGCCCCGCAGGTGATTCCCCGACCGGTCCCTGACCGGAAGTCCCAGATGCCGCAGCACGTCGCCGAGCTGGGCATCCAATCTCCCGGCCAACGCCTCCAACCAGGAATCGAGCGCCTCGCCCGCCAGGGGCGGCATCCGAATCGGCAGGGTCCGGACGCTGTCGGTCATGCCGCCGGCCGACGCCGAGATCGCGGACGGCTCGTCAGCTGCCGTTTCTCCAGAGCCGCTTCGAGCTCCTTGCGGGCCACCTCGGATGCCTCATCGTTCTTCACCCCGTCGAGCAAATCGCGGCTGAGGCGTTCGGCACCGTTGCGGACCGCCCGCTGGCAACCCCGGTTGATCAGTGTCATAAGGGAGCCGATGTGACCGGTACTGCGGGCAAAAAGGTAGTCGGAGAGATCGTCCGCGAGCATCCCGGGATGCTTGTCGGCCAGGACGACGCGCTGTTCAAGGGCCAGCAGCATCTGCCGCCATTCCCGCCTGCCGGCCTCGGACTCGATCGTGAAAGGCCGCATGCCCAGCCGGGTGGTGCGACGCCCGGTCTGCGCCAGTGCCGTATCCCGTCTGCTGTCGCCCTCGCTGAACAGACCCTTCCCGGCGAGGCCCACGCCGATCATCACGAGCGTCACCGGGAACTCGTTGGCGATCCACTTGAGGTGGTTGCTGACCTCGATGCCGTTCTTCTGATTCCACTTCAGGAAGTGCAGGTCATCGAGCGCGAGGAGGCGGACCTCGCAGGACACCACGCAGTCCAGGGCCCGCTGGCCGAACTGGGCGGTGGTCCCGCGGTTGCGCCCGGGATGGCCGAAGAACTCCAGCAGGGACCGGTTGAGATCCTTCATCCCGGTGTTGCCGGTCAGCCCGACCCGGCAGACCGGCAGGCGCTCATTGCCCGCCGCGGTGAAGGCACCCCGCTCAGCGATCTCCCTGCGATGGAACTCGCCGAGGAAGGCCAGCACCGAAGTGGTCTTCCCCAGTCCGGGGAAAGCGTCGACCGCCACGGCGCCCTTCGCCTTGTCGCCGTCCTGCACGTTGCTGTCGACGATGTCCCACAAGTCGTCGTGCAGTTCAGCCAGCTGCGGCGTCTTGATCGGCCCCAGGTTGGCATGCCACTCCCGCAGCAGCCGATCACGCTCAACTCTCGCCTCCTCGCCCAGGGCCTTCACCTGGCGGCGGGTCAGTTGTTCGGGCTGGATCCTGCGCGGAGTCTCGGCGAACGCCTTCCAGTCCTCCTTGCGCGACAGGGCAAGATTGCCCAGGCCCGGCGGGCTGGCCGTACTCACACATCCTCCAGAGCGTCGGCGTAGAAGTCGTCCTCAGCGGCGAGATCTTCCAGATCTGCGTCGTCGTCATCGCCCATCTCGACGCTCTCCGACCGCGGTTCTTCCACCGGCTCCTCCGCGACTTCGGCCTGGCCGAGGGCTTTGCGTACGGACGGAAGGGAGACGACCGTCTCCTCCTCAGTCGGAGGAAGTTCGATGGCGGCCTGCTCACGCGAGAGCCGCAGGACCATGCGCCGCTCCGCGCGGGTGGTGCCCAGCCCGAGGTTCCACCGCTCCAACAGATCAGCCACGGCGAGCCGGTCATCGGGGAAGCGGTACTTCTCAGCAGCCAGCTGCCGGGCGAAGACCAGTGCATCCTCGCTCAGCGGCATCCGAGCCGACGGCGCGTGTTCCCACGTCAGGGTGTGCCACTGGCGGGTCGAGGGGTTGCGGAAGTAGATCCGGGTGATGTCGTCCGGGTCCACCTGGAACGGCCAGCCGTTCTTCACCGGGCCGTCGTAGGGGCTGCGCAGACCCGCCGCCGGCAGGCCAGGACCGCTGTAGCGTCGACGGCCGATCTCGACGCCGTAGTGCTGGACCGTGCGCCACTTCGTCTGCAGGAACTCGAAAGCAAGGTCCCGGTCACGGGGGACCTCGATATAGCCGGCCCGCGCCATGCCGTGCTCGAACATCTTCGCCGGCGACATCCGCAGCCCCGGCACCCCCGGATCGACCAGACCCGCGTGCGGCCGGCAGTGGTAGACCGTCGCCGTCCACTCCCGGACGATGGCCTCCAACTCGTCGAGGAAGAAGAACGCGTCGTCCTCCGGGCTCTCGCCCCGGGAATGGATGTCAGGGCCCTTGTAGCCCGGCAGTACCTGCAACAGCCCCTCGCGCGAGGTGCGGAAATAGCGCTCAACCGGCCCCTTGTCACGGCCCGTTCGCAGCCGGGCAGGCTGGATCGAGATGCCCATCCGTCGACAGACGCTGGTCAGATGTTCCGAGACATAGACCTTGCCGTGATCGACGACCAGCGTCTCGGGAACCAACGGAGGAGACGCAAGCCCCGGGCCGACTGCCCCCTCGACGTCGACCAGGACCGTGCGGGGAATCCCGTGCTCGGGCCAGACCGCGTGGCGTGGCCAGTCCCGCCCCGCAGGGCGGGGCCGGAATGACTGGAAGAGCACCGCGCTGACGTCCCCCGCTTTCGTGGAGACCGGCGTGATCCGGATCCCGGTGATGCAGCGGGTGTACCAGTCCATCGCGACCGTCAGCTCGGCCTGAACCCACTTCAGCGTGAACGGATCGAACCCGAACACATCAAGCCGAGTGGAGTCCATCAGCAAGTACTCACCGGGCCGCGTCGGCCGCAGCTTCCCGTACGGACCCTCTGGACGACCCGCGATATCCCGGTTCCGCTTCGTACTCAGCCGGAACAACGGATGACGTCGCTCCAACTCCTCCAGCAGCCGAAACGCCGTCGCCCGACTCGGCTGCGGCACCACACCCTCGCCGAACCGCGCAATCACCCGAGCACGGGTCCGCTCGATCACCATCGTCCTCGACGGCCGCGACTGATCGGCGTGCTCGACCATCACCTCGACAGCAATTTCCACCCACCGGTCATCGACCGCGATCTGCGACTTCCGCGTAGGTCCCTTGCTCGGCGCGAGCCCCACTTCGCCCTTTTCCCGGAACGCGGTGACCCATCTCCTCACCGAACGCGAGGAGACCCCCAGCTCCGCGGCCTTCGCCGCGTACCTGGCTTCCAGCGATGTCGACGGTGCGTACTCATCACGGGGTTCGCCTTCACGCGCAAGTTCCGGACTCCCGGAGCGATACCCCGTCAGAAGTTCACGGACATGCTCAGCCCGTTCCAGAATCTCCCGTCTTTCCGCCTCACCAAGCTGACCCAGCACCACGGAGGCGATCTCGCCCTCGTCGTCTGCCGACGGTCCCGGACCATCAGGATTGATGGCAGCCCGGTCGGAGAACAGCAACTCCTTGAGCGACAGCCGAAGGAGACGCCCTTGCCCGTCCTTCAAGACCACTTCGTTGCCCGCAGTGGTCGCGGCCATCTCCACCACTTCGACGGTCTCACCGTCGTAGCGGAAGGACGTACCAACTCCGACTCGGACTCCCGCCTTGCTCATGCCACCCTCCTCAACACGTGCGAAGGGCCGAGCGGTCGGTCGAGATCCGTGACGAAGGTCTGCGTCCAGAGCAGATGATGGACAGCGGATCGGACTTGGAGCTCCGGACGGCCTGGCAGGCAGCCTGGCACCTGCCCCAAGACGACCCCGTCGAGGTCCACGTCCTGGAGCTCCTCCAAGACTTCAGGGCTGAACAGCCAGTCCCTGCGGTAACCCGCCAAGAACCGGATGTTCTCCAGTTCCACGGCCGGAGGCTCGCTCCAGATCTCGTACTTCCATCCCCGCGACTCCACCGCCTGCCGGGTCCAGTCGAAGGTGAACTCCACCTCTGGCTTGGACAATCGACTCAACGGCTTGACGTCGACAACCACCGGAACTTGCCCAGTGAGCAGGAGATAGTCCGGGATGTGACGGCGCACTTTCCCCTCCAGCACCGCCTTCAGCAGGAAGGGCTGAGCCACGATGCCACGTACGGACGGATCGAAGTCGGCGAAGAGCAAGCGGGACAGTTCCAGGCGGGATTCGTAGATCACGTGATTGCGCATCGTCGCCGACCAGTAGGTCCCCGAGTAGTGCTTCTGGCCCTTGTACCAACGGAACGTCCGCCACGGACAAGCCGACCGCAGAAGATCAACGGGTGCCGTACCTCAATCCCGATCTTCGACAACAGCACCGCGTTGCCGCCGAACGCTCACCGTCGCGGCGATCTCCCCCACCGCACACCCCCAAGCCTCACGAGCGATGCCCCGTGAGCCCACGGTGTCAGCGAGCTTCCATCGGAGGCACCAGCATCAGAGCCCAATCACCCATACGAGTGAGCGACTTGACCTGCCAGTCTCAGATTCGTGTCAGATATGCCATCGCTTGGCCATCGCTCGTGAGATTTGGCCACGAAATCTGAGACCCTACAGCGGCTCTGTAGGATCTCGCGGCTCGTGTCATAGAGCACTGCTCTGACCAGCGGGCCTCTGATCTGTCTCAGCTCCTGTCCGCGTGCCGGAGTCTCAGTTCCGTGGCATTTCCTCAGGACTCATACGCTCTGACCATTCGCGCTGGGTCACGGCTTGCCCGAGGCGGGTGACGATGTCCTTCTTGGACGCCGCGTCCAAGGTCTCCGGGATCTTGTCGAAGGTGTCGGGGAGGATGTCGAGGAGACCCCAGATCTGTTCACCGGTCCTGACGGTCAGTAGCTGCCGACACCTCCACTGCTGCGGCATGTCGGGTCGGTGCCTGAGGTGTTGCACGATCGTAGGGACCAAGTAGTGCGTCGCCTCTGCGGCGAGGTGCTCTTGGAGCCAGTCGACCGGGAGCCGCTGGCTGAAGCCGTGCATGGCGGCCTCCTGGGCCAGGTCCAGGAGCTGAGCGGTGTCAACGGCTCGGACGGTGCGGGGAAGGGTCGGGGTCATGTCATGTCATGTCATGTCGCGATGATGCCAAGAAGTTTTCGCGGGGCCGAGAGGTCAGCTGGGCCGGGATGCGATCTGGCGACGGGCAGGGCCCCAGACTTCCTCGAACTCCTCAGAGGTGAGTTGTTCGGGGTCGTGGCCTTCCCATTCAGAGACGGGCAGCTCGGCGGTGATCCCGAACCTGCTGTCGTACTCATCGAGACGGCCTGCGTCGCGCGCCCGCTGCCACTCGGCGAGGGAGGCAGCTGCGATCGGCGTCAGCTCAGGCCCTTCGAGTTCGACCTGCCGGATCACCCAACCTTCGGCGTCGACCTCGAAGTAGAACCAGGTGTCTTCCTCGTCCCAGTAGCAGCGCATCCATGTCTTCACGAGCCCATGATGGCGGCGGTCTGCGCGCCAGCCGCTGCGATGTCCAATTCCTGTGGATCGTCATCTGGACTACTGGGATGCTCCTGCTGTGACCACGACGACGAGCGAACTGCAGACCGGCGCCGGATGGGACGGCCCCTATTTCCGAGTCCTCGCCGAAGGGTTCGAGGCTCTGTTCCTCCCGAGCCCTGACGAGGTACTCGATGAGGTCTGCAATGTGGATGTCGAGGTTCACCTCCCCGGTGGCTCTCGCTGGAGTGCGACAATCTTCACCCTCGCCGAGGTGGACCGGCTGATGAGGGAGTGGGAGGGGACCGTAGAAGCGGCAGGGGGCCGGAGCTTCTGGTGCTCGGACGGGCTGATCGTTCGGGACCCTGGCATCCAAGGCATGGTGGACGTGATCGCCGAACTGCTTGCGTCGGGAGAGTTCGACGGAGCCTTTCATCGCCTTTCCGGCCTGGAGTGAACTCCGGATTTCATGACCCTGCACCATCTTGAGACGTGCGAATAGCCCTGAGTACCCTCCTCCCCAAGGGGGTCAGCGTCATGGGCCGGCCGCGTTCGGCTCTGACCAGCAGCGGTCCGCCGAGCTCTCGTTCGATCCGGTTGATCTGCGCGACGAGGGTGAACGTGTTGAGACCGAGGCCGCTCGCCGCCGCGCCGAGGCTGGGAAAGGCGGATGCAGCCGCGAACCGCCTCAAGCGTTCACTGGCACCCTGACCGCTTAGTGCTGGCCGGAGGAGACGCGGCGCTCGATGAGCCTGGTCGGGAGCGCGAAGTGCCTGGCTGTGGCTGGCTCCTCCGCGTGATCGCAGCGGGATGTTGTGGGTGTGGGCCCAGCGGGCCATGTTCGCGGGGCTCATGCCGGTTTCGCGGGCGAGGTCTGGCAGAGTCCGGCGGCGGTGGACGTATTGCTCGATGAGCCAGACCCGTTCGATGGTGCCGCGGCGCTTGTGGTCCTGGGGCCCTCGGAGCGGGATGCCGTACTCCTTGGCGAGATCGGTCAGCACTCTTCGGGAGAAGCCGGTGAGGGTGGCGATCTGCTGGAGGGACCGGTGTTCGTCGAGGTAGAGCCGGGTGAAGCGCTCTGCCGGAATGGCTTGCCGGGCCTGCTGCCGGATGCGGCCGGTGGCCCTGGCGGTGCTCTTCGTCAGCGGGGGTGCGGGGGCTGGATGTTCGTCGAGGGCATGTCGGATGGCCTCGACGGTCGTGCCCAGGACCTGGGCGGCGTGCTGAAGGGGGTGCTGGCGTTCGCGGACAAGCTGGTGCAGACGGGGTAGGTCGACGTGTGCCGGGTCGGGGCCGGGAAGGGAGAGCCCTGCCAGCAGGGTGGCGGGCGGCTGCCAGGTCATGGGCTCGTCGTGGATGTGGTGTGAGGCCAGGAAGTTGAGGGCTTCATGCTGGAGGGCATGCACGAGTTCAGGGGTCTGAAGCGCGGTGAACCGCAGGGACGTCGCCCGGAACTCTGCACTGTCGGGCCCGCCCAGGTCGTCGGGGGCAGACTCGGCGGGCAGGCCGCTGAGACGTTGGAAGAGCTGGCTGCGTGCGATGCGTTCGCGCCGTCCGGTTCCCGGTGGTGTTCCGGTGCGGCGGCAGATCTCCAGCCAGCGGTCATGAGGAAGCAGGCCGGTGTAGTCGAGGAGTCGGCGCCGGCCGTAGTCGATGGGGGTGCTGGTGGCGTCGAGGTGGTCGGCAAGCCGGTCCAGAGCAGTGGCGATGTCCGGCCATTGCGGAAGGTCGTCGACTTCCTGGAGGAGGCGGGAGACCTCAGTGCCGTCGATGACGTCACCGATCAGCCCGGCTGCCTGGTCCAGGGATGTGCGGCTGTCGGGAATCAGCAACAGGGCGGCGAGAACGGGGGCCAGAGCCCGCGCATGGATTCCTTCAGGTGGTGCGAGGCGGATCGTCCAGGGTGGCCAGAACATCGTGGGGATCTTCCTGGCTCGCTGCTCGATGTCCCGAGTGGTCCGGGTCGGCCGGCGGGGGGTCTCGGTCATGATGCGGTAGCGGACGTATTCGCTGGGGCGGAGGGAAGGGGCGAGGGCCGCCAGGTGCACGGACTGCAGCACCGGGCTGATGCCCATGCCCCAGCTGTCGATGCTGGTCGCCGAGATCTGCGTGAGTTCCTCGCGTACTGCTTCCAGCAGGCTCCGCAGGGCCTCGCCGGCCGGGTGGATTCCTGGTTGCTCCAGGATGCTCAGGGCCATGGTGACCGCGACGGCCGTGTCCGCGGCTCGGGGCGGGGCCATGAACCCCGGACGTTCCATGGCCTGTCCGGTGTGCGGGGAGACCGCATCGGTGCTGAGGTGAGCTTCTGCGATGTCAGCCGGGATTTGTTCTTGTAGGACAGCTGCGGGCAGGTCGCTCAGGACGCGTATGCCCAGGGCCCGGATGTCGGCCAGCACCGCCGAGGCCGGCTGGGGAGAGGTTCGGTAGGGGCCGAAAGCTGCCGTTGCCCCGTCGATGATCTCCATCACTCGGTCCTGCGCCGTGAGAACCGGATGGCCAGGAGGCAGGAGGAGCGTCGAAGCGCGGGTCAGATCGGTGCCGCAGCCCGCCGAGAACGGGCGGGTGGGGCGGGTCGGTGGATTGCCGCAGAGTTCAGGCCGGGGGACGGACCGGCCGGAACGGGGCCGCTGCCGCGGCACCCTCCCGCAGTGCGGGCAGCAGTCCGCCAGCAGCCTGCGGTGCCGGGTGCAGGCGAAGGAGAAACCGAGCCTCCAGGACAATTGCCATCGCCCACCAGTGGCATGAAGGCACTCCGGACAGAACCGGGATCCCCCTCCGCGGCCCCAAAGGACGTGCCGTGACACGGCCCGGCCCCCGGCACTCAGGTGGAGGGCCCGTCCGTCGTAATGAGCCAGGGTCAGGGCAGCGACTGTCTCCGGGGACGTCCCGGTGGCGTGCGCGACGGCATTGGTCTGCTGCTCGTCGAGGACGATCGTCCAGTCTGCCGGGATGCCCCTGAACTGGTTTCCGGCCCGGTGCCGGACCGGGAAGCCGAAGTGCAGCAGGACATCACCGAGCGCGGTGTCCATCCGTCTTGCTATCGCCTCCAGCCATGAGTCCAGGGCCTCGCCGGGCAGTGGAGGCAGCCGGATCGGCAGGGTGCGGGCCGGCGTTCTCATGCGGGTCGCCGGCTCCGGGGCCGCGGGCGGCTGGTCAGCCGTTTCTTCTCCAGCGCGGCCTGCAGTTCGAGGCGGGCGGCCTCGGATGCCTCGTCGTTCTTCACCCGGTCCATGAGCTCCTGGTCAAGACGTTCGGCGCCGGTGCGGACCGCCCGCTGGCAGCTGCGGTTGATCAGCGTCATCAGCGAGCCGATGTGTCCGGTGCTGCGGGCGAAGAGGTAGTCCGACAGGTCGTCCGCGAGCATGCCGGGATGCTTGTCGGTGAGCACGACTCGCTGTTCGAGGGCCAGCAGCATCTGCCGCCACTCCCGGCGCCCGGCCTCCATATCGATGGTGAACGGACGAAGCCCGAGGCCGGTGGTGCGGCGGCCGGTCTGGGCCAGAGCGGTGTCGCGCCCGTTCGTTCCTTCGCCGAACAGGCCCTTCTTCGCGAGCTCGACCCCCACCATCAGCAACGTCACCGGGAACTCGTTGGCGATCCACTTCAGGTGGTTGCTCACCTCGATGCCGCTCTTCTGTCCCCATTTCAAAAAGTGCAGATCGTCCAGAACCACCAGGCGGACATCACAGGACAGCACGCAGTCCAGCACCCGCCGTCCGAACTGGGCGGTGGTCCCCCGCATCTGTCCGGGGTGGCCGAAGAACTCCAGCATGGCCCGGTTGAGATCCTTCATTCCGGTGTTCCCGGTCAGCCCGACCCGGCAGACCGGGATCCGCTCGTGCCCTTGGCTCGTGAACGCGCCCGACTCCTCGATCTCCCGCTGGTGGAAGTCGCGGGCGAAGGCCAGCACCGAGGTCGTCTTGCCCAGACCCGGGAACGCGTCGACGGCCACCGCCCCCTTGGCCTTGTCGCCGTCCTGCTCGTTGCTGTCGACGATGTCCCATAGGTCTTCATGGAGCTCTGTCAGTTGCGGCGTCTTGACCGGGCCGATGTTCGCGTGCCACTGCCGGCGCTGACGGTCGTAGTCCGCCCGCGCCTGTGTGGGCAGGGACTTCAGCTGCTTGCGGGTCAGCAGGTCGGGCCGGCTGCGGCGAGGGCTCTCTGCGAACGCCTTGAAGTCCTCCTTCCGCGACAAGGCAAGACTGCCTGGCTGCGGAACGCTGCCGTCGTTCACACGTCCTCCAGGGCATCGGCGTAGAAGTCGTCCTCCCCGGCGAGGTCCTCCAGATCGGCCTCGTCGTCATCCCCGGTCTCCGTCACCACGTCGGGCTCCCGCAGTTCCGCGGTCTGCTCGTCCTGGCCGAGGGCCTTGCATACGGACGGAAGCGAGACGACCGTCTCCGCCTCACTCTCCGGAAGCTCGATGGCGGCCTGCTCGCGCGAGAGCCGCAGGGCCATGCGCCGCTCGGCGATCGTGGTGCCCAGCCCGAGATTCCACCGCTCCAACAAATCAGCGACGGCAAGCCGGTCGTCAGGAAAGCGATACTTCGAGGCCGCCAGCTGCCGGGCGAACGTCAACGCGTCCTCGCTCAGCGGCATCTCGGCCGATGGCGCGTGCTCCCAGACCAGCGTGCGCCAGGCCCGAGTAGCCGGATCGCGGAAGTAGATCCGGGTGATGTCGTCGGGGTCCACCTGGAAAGGCCAGCCGTTCTTAACCGGACTGTCGTAGGGGCTACGGACTCCCGGCTCGGGCAGGCCCGGGCCGCTGTAACGGCGCCGGCCGATCTCGACCCCGTAGTGCTGGACCGTGCGCCACTTCGTCTGCAGGAACTCGTAAGCCAGGTCCCGGTCGCGGGGCGCTTCGATGTAACCCGCCCGCGCCATGCCGTGCTCGAACATCTTCGCCGGGGACATCCGCAGACCCGGCAGACCCGGATCGACCAGACTGGAATGCGGCCGGCAGTGATAGACCGCCGCGGTCCACTCCCGGATGATCGCCTCAAGCTCGTCGAGGAAGAAGAACGCGTCGTCCTCCGGGCTCTCACCCCGCGAGTGGATGTCGGGGCCCTTATAGCCGGGCAGCACCTGCAGCAGCCCCTCCCGCAAAGTCCGGAAGTAGCGCTCGACCGGCCCCTTATCGCGGCCCGTCCGCAGCCGGGCCGGCTGGATGGAGATGCCCATCCGTCGGCAGACACTGGTCAGGTGCTCCGAGACATAGACCTTGCCGTGGTCGACGACCAGCGTCTCGGGAACCAAAGGCGGCGAGGCCAGCCCCGGCCCGGTGGCGCCTTCGACATCGACCAGGACGGTGCGGGGGATGCCATGCTCGGGCCAGACCGCGTGCCGCGGCCAGTCCCGCCCCGCCAGCCGCGGCCGAAACGACTGGAACAGCACCGCACTGACATCCACCGCCTTCGTCGAGACCGGAGTCAGCCGGATCCCCGTGATGCAGCGGGAGTACCAGTCCATCCCGACACTCAACTCGGCCTGAACCCACTTCAGCGTCAACGGGTCAAACGCAAAGACGTCCAAGCGGGTGGAGTCCATCAGCAGATACTCACCCGGACGCGTCGGCCGCAGCTTCCCGTACGGACCCTCCGGCCGACCGGCGATATCCCGGTTCCGCTTCGTACTCAGCCGGAACAGCGGATGGCGTCGCTCCAGCTCCTCCAGAAGGCGAAAGGCCGTCGCCCGGCTCGGCTGCCGCACCACCCCCTCACCGAACCGCGCTATTACCCGAGCCCGGGTCCGCTCGATCACCATCGTCCGCGACGGCCGCGACTGGTCGGTGTGCTCGACCATCACCTCTACCGCGGTCTCCACCCACCGATCATCAACTCCTGAGTGGGGTCTTTCTGTTGTCTTCTTCGGCGCGAGCCCGGCCTCTCCGCCACGACGAAAGTCAGAGACCCATTGCTTCACGGCACGAGGTGATACCCCCAGCTCAGCCGCCTTTGCCGTGTATCGAGCCTCCCACGGTCGCTCCGGGCGATAGTCCGGTCGGGGCTCACCATCGCGTGCCAGTTCCGGAGCTCCAGACCGGTATCCCGTCAGAACCTCCCGGACGTGCTCAGCGCGTTCAAGGACTTTCGCCCGTGCAGAGCTGTCGAGCTGCCCAAGTACGACCGAAGCGATCTCCTCTTCGTCGTCGGCTGACGGTCCCGGGCCGTCTGGACTTACAGCGGCACGGTCCGAGAACAGAAGTTCTTTGAGTGACAGGCGCAGCAATCGCCCCCGGCCATCCTTCAGGACCACTTCGTTGCCTGCCGTGGTCGCAGCCATCTCCACCACCTCGACGGATTCCCCGTCGTAGCGGAAGCGCGTACCGACCCCGACCCGAGCCCCTGCTCTACTCATGCCACCCACCTCAGAACGTGTGAAGGGCCCAGCGGCCGATTGAGGTCGGTAACGAGAGACTGCATCCAGAGCAAATGATTGATGGCAGAGCGGACTTGGGACTCCGGACGATTCGGCAGACAGCGCGCGGCCTGCCTCAGAGAGACACCATCGAGCTCAGCTCCCCGAAGGTCTTCCAGGACCTCTGGGCTGAACAGCCAGTCCCGTCGGTAGCCCGCCAGGAACCGGATGTTCTCCAGCTCCACGGCCGGAGGCTCGCTCCAGACCTCGTACTTCCATCCCCGCAACTCCACCGCCTGCCGGGTCCAATCGAAGGTGATCGCCACCTCTGGTTTGGACAACCGATGCAGCGGCTTGACGTCGACGACCACCGGTGCCTGCTCGGTGAGGAGGAGATAGTCCGGTATGTGCCGACGGACCTTCCCCTCCAACACCGTCTTCAGCAAGAAGGGCTGGGCCACGATGCCGCGTACGGCCGGATCGAAGTCGGCGAAGAGCAACCGCGACAGCTCCAGTCGCGACTCGTAGATCACGTGATCCCGCATCGTCGCCGACCAGTAAGTGCCGGAGTAGTGCTTCTGGCCCTTGTGCCAGCGGAACGTCCGCCACGGACAAGCCGACTGCAGGAGATCGGCAGGCAC

Protein sequences of DBSCAN-SWA_2

>NC_020990|3322761:3380877|3380232_3380877_-|WP_101277829.1|transposase|DBSCAN-SWA
MPADLLQSACPWRTFRWHKGQKHYSGTYWSATMRDHVIYESRLELSRLLFADFDPAVRGIVAQPFLLKTVLEGKVRRHIPDYLLLTEQAPVVVDVKPLHRLSKPEVAITFDWTRQAVELRGWKYEVWSEPPAVELENIRFLAGYRRDWLFSPEVLEDLRGAELDGVSLRQAARCLPNRPESQVRSAINHLLWMQSLVTDLNRPLGPSHVLRWVA
>NC_020990|3322761:3380877|3344172_3345294_+|WP_003949441.1|DBSCAN-SWA
MTAAGKHQVSRADTTRRGSRPVRAGIRDVAAAAGVSITTVSDALNGKGRLPDATRRHVREVAERLGYRPSAAARTLRTGKSGLIGLTVTTYGDEPFTFTEFAYFAEMARAATSAALARGYALVILPATSRLSPVDVWSNVALDGTVVVDPADDDPVVRELARQGLPVVSDGRPAGSLPVTAWVDNDHEAAVLDILDHLAAAGARRIGLLTGTTTDMYTRLSTAAYLRWCARIGQDPVLEAYPAHDPCAGAVAADRLLARPDRPDAVYGLFDPNGTDLLAAARRYGLRVPDDLLLVCCSESTVYASTEPPVTTLSLKPRRIGTAVVQLLIDAIEGINQDQPVEQVIPTELIVRTSSMRRSPRTTVNPPRSPRQG
>NC_020990|3322761:3380877|3366103_3368848_-|WP_015507533.1|DBSCAN-SWA
MTDSVRTLPIRMPPLAGEALDSWLEALAGRLDAQLGDVLRHLGLPVRDRSGNHLRGIPSDWTILLNEHQIAAITRASGLDEQIVRGMTLAHFDSRAVSINFERRYVNRRVLWGRGSGSRFCPDCLRETGGRWQLFWRLGWAFACPRHGCLLADCCPQCERIPRQRPRSGRVVPHLGVCGNPAANDDSLVSGGCDFDLSQTRTLRLPAAHPVLGAQEVLMNVIETDIADFGAYALDPQPSRAALADVRAIGGRVLADLPAHDIRSLVPVDIAEDYYTVDPGSPLARRAVERPGFMAPPRAVSTAVAVSIALRVLGQSDVHRAGTELRGLLEAMREELWQISATSIDSWGRGLSPVLGAVNLAALAPSLRPSEHLRYRTPTAMPRFPKRTVREIEDRARKVPSMFWLSWTVRLTPPDGVYPRILAPVLAAALLVVDSKVPLEDAAEHLGSVTDSIGISRILQVLDDQPHWSDSVAALVRLSDHLDATEVPIDYQRRRRLDYSQLLPHEHWRDICRRTGALPGNGLRERVVRCQLFQRISGLPAESAPDHSSINEARFRAEVARFATIQTPDLAQALAEEACTFLAAHGIHDEPVTWQPPLTLLSGLALPGPDLDGIDVAQLHQFVRQHKSPVRHAAETFGTNIEVIRLVLDEQPAPALPPTETIAKATGLIRFKARQEVPKETFTSLYLDEHRSLQQIAEHTGFSRQTLSALAREYGIPIRDGPQDYKRRGTIERAWLIEQYVVRRRTLPDLARESGTSTANMARWAHIHKIPLRPRGGGSHKTALKVTSQTASTPAILRKALTSAFAWQRLERFAAASSYPTIGEAAKALSIHPSALAIQINRLERDLGKTLLERAVRGRAMKLTSFGKKIVAAVCTRSSSKRRPDTQDDPPVGCLGGLCRGPFQSARISMTVGR
>NC_020990|3322761:3380877|3355523_3356429_+|WP_003949430.1|DBSCAN-SWA
MDLALLRTFVTVHRAGSFTRAAALLGLSQPAVTSQIRTLERQLGRPLFLRKARGVTPTSVGDELAHRAAPHLDALVEIAEGGLEVEAPLRTLHLAGPPEFMAERVLPALVGMTGAEGPAVRLRTSFGSTDDVLEGLAAGHHDLAVATRRPRGTLLSAGTLCDEEHLLVAGARWAGRFAPGAVRRGGAEALAKVPVVDVHESLPFARRYWTTVFDAPPPEHAALVAPDLRAVLSCVVSGAGLAVLPRYLCEDALLRGELVTLLEPPVPPLRTYFVAVRAGTQALPHIATAHEWLLRAAVAWG
>NC_020990|3322761:3380877|3363570_3364341_+|WP_003949000.1|transposase|DBSCAN-SWA
MAGVITASEPSWIAPFSGLSPRQFGKLVTVLRREGADAVRKGRPWSLPLEDRALLVAAYWRTNLTMRQLAPLFGVSKSAADRIIDHLGPMLALQPRKRFAKDTVLIVDGTLVPTRDHTIAERSKNYRYSTNHQVVIDADTRLVVVVGRPLAGNRNDCKAWEESGAKAAVGKTLTIADGGYPGTGLVIPHRRERGQAGLPDWKEEHNKSHKQVRARVEHVFARMKTWKILRDCRLKGDGVHHAMLGIARMHNLALTG
>NC_020990|3322761:3380877|3373958_3374336_+|WP_015507537.1|DBSCAN-SWA
MTTTTSELQTGAGWDGPYFRVLAEGFEALFLPSPDEVLDEVCNVDVEVHLPGGSRWSATIFTLAEVDRLMREWEGTVEAAGGRSFWCSDGLIVRDPGIQGMVDVIAELLASGEFDGAFHRLSGLE
>NC_020990|3322761:3380877|3347809_3349603_-|WP_003949438.1|DBSCAN-SWA
MTTQDARTPASAPKSEAGKSIGWHKAYIEGSRPDLRVPVRQVHLTNGNAVTLYDTSGPYTDPAVETDVRRGLTPLRDHWITARGDTEEYAGRPVRPEDDGIKHTSPRGGLRNLDAVFPGRPRKPRRAVPGRAVTQLAYARRGEVTPEMEYVAIRENLDPRTVRDEIAAGRAVLPANVNHPEIEPMIIGKRFLVKVNANIGNSAVTSSIEEEVEKMTWATRWGADTVMDLSTGRNIHTTREWVLRNSPVPIGTVPLYQALEKVDGKAEELTWEVYKDTVIEQAEQGVDYMTVHAGVRLAYVPLTARRKTGIVSRGGSIMAAWCLAHHQESFLYTHFEELCEILAAYDVTYSLGDGLRPGSIADANDEAQFAELRTLGELNTIAKRHHVQTMIEGPGHVPMHKIKENIDLQQEICEEAPFYTLGPLTTDIAPAYDHITSGIGAAMIGWWGTAMLCYVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPGAQDWDDALSDARFEFRWEDQFNLALDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMKISQDIATRFGDSAGDGASQEEIEAGMLQKSKEFAESGNRVYLPLAD
>NC_020990|3322761:3380877|3331344_3332247_-|WP_010644320.1|DBSCAN-SWA
MSLRLSTVILPVDRWHEGGRATWQRAEELGFHTAYTYDHLSWRTFRDGPWFGALPTLTAAATATERLRLGTLVTSPNFRHPVTLAKELISLDDVSGGRVTLGIGAGGNGFDATALGQEAWTPKERADRFAEFVPLLDRLLTEDAVSQRGTFYSAEEARNIPGCVQRPRLPFAVAATGPRGLRLAARHGQAWVTTGDPKLYETGTPEQSVEALRGQIGRLGAACEEAGRDVADLGKVLLHGFTPDRNRPLDSVDAFVEFAGRHQELGFTEIAVHWPIAGSDFAADQAVFEKIATEAVGQLS
>NC_020990|3322761:3380877|3353635_3354016_+|WP_003949432.1|holin|DBSCAN-SWA
MTNFLVKTLANAAALLVAVWLLNDITLTGDSTGNKALTLIVVALIFGLVNFLVKPVVKVLTFPLFVLTLGLITLVVNALMLMLTSWLAGQFDLSFHVDGFWTAVLGGLIISVVSWALNVALPDRKD
>NC_020990|3322761:3380877|3359358_3360762_-|WP_015507529.1|DBSCAN-SWA
MTTHETPEDLSLLPATRRALRHRLARAQSESRVPSLVAGVARDGEVIWEGALSALEGVEADGDTQYRIGSISKTFTAVLVMRLRDEGLLELTDPLEKHLPGTGAGRATVADLLSHTGGLAAEAPGEWWERSPGTLRPELADVLGEEPHRHPVGRVHHYSNPGYTLLGALVEEVRGEPWEKVLRAEVLEPLGLTRTSYAPQAPYAQGWAVHPWADTLLPEPAHDLGRMAPAGQLWSTTRDLLRFAAFLVQGDDAVLGAASVREMRTPAAPSLPGAQESAYGLGTQVLSVGGGITLTGHMGSLPGYLAALLTREDEGLAAVVLANTTSGPLIGSLAAELIGIVAEAEPSMPRLWRPMSEADPRVLELAGAWYWGVTPYGLHYGADGVVELRPLKGVGRAARFVPAGDGTWRGLDGYFLGETLRPVRDAEGAVTHLDLGSFVFTREPYAPDSVVPGGVDAKGWRATGELG
>NC_020990|3322761:3380877|3356475_3356958_+|WP_003949429.1|DBSCAN-SWA
MTVRSVVKRTARAVLLDGDQLVLIKRTKPGVDPYWVTPGGGVEPEDSSVVAALHREVLEELGAKITDVVPCFVDTVEHIGEDAETTGVKVQHFFVCRLGSMDPALRHGPEIEEPCGEYEIVRIPFTRLGIASVHMVPLSLRHYLDGNIEGVQALLAPDLG
>NC_020990|3322761:3380877|3333295_3334342_-|WP_003949447.1|DBSCAN-SWA
MSSRDRRHLFLPVLCALLALGYLAPHDASGDTPPDPGAEVARLYEQASDATQRYEAGLRASRAQRREAQRLERRLAEERRVLATYRADLGRIASAQYRAGAGLPYTARLLLADDPEGLLRSQHAANQADLAVTNAIGRTQRAERRLAEGERTAAKVSRTLARRADELGRLKTRIETQLRDAQQRLERQAETSVTAGKCRGAVRLGNAGSPARTGRPWMTPVRSYTLSAGYGGQGDRWANRHSGQDFAVDTGTPVRAIGAGRVIRVGCGGAYGIEVVVRHDGGYYSQYAHLSAPAVDQGDRIQAGDWIGQSGSTGNSTGPHLHFEIRLTPYYGSAVDPGPWFAERGVVL
>NC_020990|3322761:3380877|3362626_3363196_+|WP_003949421.1|DBSCAN-SWA
MRKLIYGMNLSLDGYIAAPGDDIGWSGPPSDELFQWWLDQEQASGLTLYGRKLWETMSAYWPTGDQQPDATPAEIAFARNWRSTPKVVFSSTLDGPLDWNTRLVTGDALAEITRLKAGDGAPLQIGGATLAAAAMRAGLIDEYAIATHPVLVGGGTPFFGPLDGWVNLNLLETRTFPGGTVLTRYETRR
>NC_020990|3322761:3380877|3358189_3358648_+|WP_003949427.1|DBSCAN-SWA
MTATDPALTALAQSWCALSLLHGRIETHVERALQSGHGLSTREYSLLDVLSRQHDGEGGHLQMKQVADAVVLSQSATTRLVSRLEDRGLLSRYLCPTDRRGIYTDVTPAGRALLDEARPTNDTALREALDTAAQNPELAPLVQAVETLRTPA
>NC_020990|3322761:3380877|3325626_3326538_-|WP_015507520.1|DBSCAN-SWA
MTTLTIDHASRWFGNVVAVNDITMTIGPGVTGLLGPNGAGKSTLINMMGGFLAPSTGTVTLDGDAVWRNESVYRQIGIVPEREAMYDFLTGREFVVANAELHGLDAAAAARALATVDMEYAQDRKIATYSKGMRQRVKMASALVHDPSVLLLDEPFNGMDPRQRMQLMELLRRMGEEGRTVLFSSHILEEVEQLASHIEVIVAGRHAASGDFRRIRRLMTDRPHQYVVRSSDDRALAAALIADPSTAGIEVDTQEGMLRVQAVDFGRFTALLPRVARDHGIRLLAVSPSDESLESVFSYLVAA
>NC_020990|3322761:3380877|3364496_3364868_+|WP_003949420.1|DBSCAN-SWA
MADTKVVFVAFAIEDERQRDFLKGQSLSPRAPYEFIDMSVKEAYESGWKDKVRTRIRRSDGVIVLVSKNSLTSEGQEWEIKCAKEEGKKIRGIWAYSDDRTQLAGVTTVVWSDANISSFIDSL
>NC_020990|3322761:3380877|3361927_3362470_-|WP_003949422.1|DBSCAN-SWA
MADDRLMRIHSDEFRAMSERVLRATELTSRLNVLPFEDEAGKAELFERILGRPLPARTTIYPPFYTDHGLHLELAERVFINQNCTFLDYAGIRLGERVMVGPKATFITLGHPVDPGARREWLSGGPIDVAENVWIGAGATILPGVSIGRDAVIAAGAVVAEDVPPATLVTGPKATVNRQW
>NC_020990|3322761:3380877|3373555_3373858_-|WP_015507536.1|DBSCAN-SWA
MRCYWDEEDTWFYFEVDAEGWVIRQVELEGPELTPIAAASLAEWQRARDAGRLDEYDSRFGITAELPVSEWEGHDPEQLTSEEFEEVWGPARRQIASRPS
>NC_020990|3322761:3380877|3351792_3352611_-|WP_003949435.1|DBSCAN-SWA
MAHATPADRPDHWSTGSHQDDGHAAPTLIGSVQRALRLLEAAALHEGGAPAKQLAREAGVALPTAYHLLRTLTHERYLRRVDGVYVLGPAVGRLDEAHAQQSRRHLIDDVLRHWHERLGAPVYFALYRDGEVDLVATADTPGNPAVAEWADFRETAHAHAIGQCLLSQLDEEGRRDHLSRHPVRPLTPYSVPDSQRLLRRLAAAERMQPVVEYQQYALGVACAAVPITVGSTAAVLAVSLPAAQAERLRVTTQLLHRDVGSIMRRLRFSISI
>NC_020990|3322761:3380877|3336258_3339924_-|WP_003949445.1|DBSCAN-SWA
MKPIDPRLLRYARATRFFLAAVVVLGALGAGLVIAQAMLLAELIVSSFEQRFDTGDLTTPLLLLVAVALGRALVSWLTELAAHRASAAVTSELRMRLVERAGQLGPGWLGDRRTGSLIALATRGVDALDDYFARYLPQLGLAVVVPVAVLARIVTEDWVSAAIIVVTLPLIPLFMALIGWATQSRMDRQWGLLSRLSGHFLDVVAGLPTLKIFGRAKAQAESIRRITHDYRRATLRTLRIAFLSSFALELLATLSVALVAVTIGMRLVHGDMDLYTGLVILVLAPEAYLPLRQVGAQYHAAAEGLAAAEEVFAVLETPVPHTGTQAPPAGALAFEGVTVRYPGRDAPAVREATFTVEPGETVALVGPSGCGKTTLLQAALGFVAPAEGRVTVGGTDLAEVDRELWHQRIAWVPQRPQLFAGTVAENVRLARPDASEAEVARALEQAGAREFVAGLPAGAETELGEDGAGLSAGQRQRVALARAFLADRPVLLLDEPTASLDGASEEAVVEAVRRLAVGRTVLLVVHRPALLAVADRVVRLDEVTKASAGEDERGVPAQRGATVRTPVVSAADSMTVADGPRGVDVSRETRPEEWEWFFSDVSRETTSRPEESEADVSRETSAAEATADRRLPGRGSALVRVRAAGREARGRLILSLVLGSLALGSAVGLMATSGYLISRASQQPPVLYLMMAVTATRAFGIGRAVFRYAERLVSHDVVLRMLADTRVAVFRRLERLAPAGLRGTRRGDLLSRLVADVDALQDYWLRWLLPAGWAALVSTVSVLFMTWLLPAAGAVLAIGLLAAAVGVPLVSGGFARRAERRLAPARGALATRVAEVLTGTGELTVAGALAHRTARTGDADRELTRIRARGAAANALGAGLTAVITGLTTVAAAYVGIRGVSAGALDGVALAVVVLTPLAAFEAVTALPLAVQFRQRVRRSAERVHEVLDAPVPVTEPEAAGPAPESPFPVELRGVAARHPGQARDALTGIDLTVTEGRRIAVVGPSGSGKTTLAQLLLRFLDPRTGSYTLAGASAPGLDGDDVRRLVGLCAQDAHVFDSTLRENLLLADRSATEARLREVLGRARLLEWAETLPQGLDTPVGEHGARLSGGQRQRLALARALLAGFPLLVLDEPAEHLDLETADRLTADLLAATRGRTTLLITHRLAGLEAVDEILVLDEGRIVQRGTYEELSAEDGPFRRLRERERATDALLLGRAGVPA
>NC_020990|3322761:3380877|3354195_3355320_+|WP_015507527.1|DBSCAN-SWA
MTGEGTRAVRAGLPEAVKNEPTLPGPVFAAHFHLPGDVSGPYSYGRDSNPTWTHLERAIAELEAPGEEAHTLVFASGMAAIAAVLFSQVGTGDVVVLPDDGYQALPLVREQLTAFGVEVRTAPTGGDAQLEVLEGAKLLWIETPSNPGLDVCDIRRLVEAAHAQGTLVAVDNTLATPLGQRPLELGADFAVASDTKGMTGHGDILLGHVTCRDAELAAGVQRWRKIVGAIPGPMEAWLAHRSLATLQLRVERQTANALALAEALRARADVTGLRYPGLPDDPSHAVAARQMRRFGSVVSFDLGTRERAERFLAALRLVEDATSFGSVRSTAERRGRWGGDAVGEGFVRFSVGAEDAEDLLADVTCALDLSLDGA
>NC_020990|3322761:3380877|3351257_3351668_-|WP_015507526.1|DBSCAN-SWA
MMSFLVSEELAFRIPVELRYETVDPYAVRLTFHLPGDAPVTWVFGRELLVEGVLDAAGDGDVRVCPVGQTATREVHITLQVGSEQALFRVGKAPLLAFLDRTDRLVPLGSERAHADFDSHLDDALNRILAEEQSAG
>NC_020990|3322761:3380877|3327412_3328438_-|WP_003949452.1|DBSCAN-SWA
MIATESLSKRYPKVTALDRLTMDVGPGVTGLVGSNGAGKSTLIKILLGLAPASEGRAEVLGLDVSTHGGAIRERVGYMPEHDCLPPDVSATEFVVHMARMSGLPPTAARERTADTLRHVGLYEERYRPMGGYSTGMKQRVKLAQALVHDPDLVFLDEPTNGLDPVGRDDMLGLIRRIHADFGISVLVTSHLLGELERTCDHVVVIDGGSLLRSSSTRDFTGATTTLAVEVTDTETHPDGTAALLAALRDRGVTAGSGGVLPGAGHSLLLEEADDETRDLVRDLVVDLGLGLVRMEQGRRHIADVFQADAAGTGQPPQHDPAEPPPAAAAESLRPTAGGGRS
>NC_020990|3322761:3380877|3324059_3324884_+|WP_003949455.1|DBSCAN-SWA
MSPVRPAPVFPYKLVATDLDGTLLRPDDTVSERTREALAAATAAGAAHIVVTGRSVAWTRHVLDDLGYEGIAVCGQGAQVYHAGEQRLLTSLTMDRRLAVLAIEKIEAETGPLHLAAARDGLHGEVLIGPGYQVQDGPLASVPSTDRDSLWAEPISKVYLQHPTLGDDELAAAALRIAGDLVGVVMAGPGVVELLPLGLSKATGLSLAARRLGTKGAETIAFGDMPNDIPMFGWAGHGVAMANAHRELKAVADELTTSNAEDGIAVVLERLLTG
>NC_020990|3322761:3380877|3328734_3330552_+|WP_015507521.1|DBSCAN-SWA
MGGLSGARERSVHTGGVELRVAELGDASRPTVVLVHGYPDSKEVWSGVAARLADRYHVVLYDIRGHGRSTAPRPLRGGFTLEKLTDDFLAVVDAVSPDAPVHLVGHDWGSVQSWEFATVERTRGRVASFTSLSGPSLDHFGHWIKKRAARPTPRRLAQLVSQGAKSWYVYMLHTPVLPELAWRGPLGKRWPRILERLEKVPAGDYPTSSLGNDAAHGAWLYRDNVRTRLRHPRPDPYAHAPVQLITPTGDIFLSERLYDELESWVSQLVRRTIPAKHWVPRTRPDQLAAWIGEFVDSQEALRQSGRATSLTLVEGGRPRGSARRRAALARYAERFAGQLVLVTGAAGGIGRATALAFAAAGARVIAADRDGAGAAGTARAALAAGAPHAWAETVDVGDEQAMEKFAAKVAAEYGTVDVLVNNAGVGLSGSLLDTTPEEWRRVLDVNLWGVIHGCRLFGRQMAERNQGGHIVNLASAAAYLPSKTLTAYSTSKAAVLMLSESLRAELAPRSIGVTAICPGIVNTGITRTSRFAGASKEDEAKHQQRAAKLYGMRNYPPEKVADAILRAVLDNSAVVPVTPEARGSRLLARLSPKGARAFARLNPPV
>NC_020990|3322761:3380877|3357158_3358037_+|WP_003949428.1|DBSCAN-SWA
MSTPALSALPVRPLTLRDLPACTSLAYDRGWSPEEHKWRLLLAAGHGVGVDAPDGRGLLGACTLTDFGPHEAPAFTAIGMMLIADRYAGRGFGRRLLEHVVQYSERVPLTLYASGSLLPLARKLGFTSVGRAATATGRLTGPTALPERPRLTLSPARAGDLPRILQLDAEVFGTDRTPLIARLPAFADRFLVAEEDGELTGFAARWPNTATEVVGPLVARDTRTAQALITGLAEGSTRPLRVDVDVRHTALLEWLGERGMPVVATSELMTRALPGLPGDWTRRFAPLTVAAA
>NC_020990|3322761:3380877|3364878_3365859_+|WP_003949419.1|DBSCAN-SWA
MRKALIVGIDYYEKIGSLNGAVNDAHSVKTTLERNADGTRNFAQPNLMTSTGPGSDVTRAELREAIEQLFQDDAEVALLYFSGHGYIDGIGGYLCASDFATEHDGLSLADIMGYANKSPAKNKVIILDSCHSGAAGGSAVSAKVAEISEGVTILTASAANQYAVETGGSGVFTSLFVDALSGSAANLVGEVTPGSVYAHVDQSLGPWSQRPIFKTNVKEFVSLRKADAPIELEKLQKLVELFQEPTTLLQLDPSYEPERTGAEDPSVPAPDPVKNADFAVLQALVRVNLVRPVSAPHMWHAAMNSKTCELTVLGQHYWSLVKQGLI
>NC_020990|3322761:3380877|3334465_3336181_-|WP_003949446.1|DBSCAN-SWA
MPPPAENRSGSLPDEADLPGPHGISAELAVRIPQLLAAMRSVGSGTELHQTLDKLCETAAELGGARYAAIGVVAEDGQGLSDFVHHGVDGATARAIGHLPDGHRGLLGALIHDPRPLRLADLATDPRSCGFPPHHPPMRSFLGVPIRVGEEIFGNLYLAEKEGGADFTEEDLQILRVLATEAGIAIGNARLHEASKQRERWIDGSVAVTTSLLSGSDADEALTVVAEQARHLADARAGFVLLPTEGGGMEVVAASSREDEPRGAMGLVVPADSALVRELLAGRPVLVDDAAGDPRVRTEVGAGFGPSMMLPLVSDDRVLGALVTPRSVGARHFTETERTLATQFATQAALALRMAEAQRDRERLAVLEDRDRIARDLHDLVIQRLFATGMMLETAQRRSDAPAVREKLGKAVDELDVTIQEIRTAIFALQQGPADAPTGLRTRVLREINLAAVPLGFTPAHRFLGPVDTLVGETTGKNLVAALREALSNAFRHSGAGRIEVVVEAGRALPDGTPGVRLTVADDGVGIAPGGRRSGLRNLRRRAESLGGSSWYGPGIGEGGGGTSVVWEAAL
>NC_020990|3322761:3380877|3365858_3366140_+|WP_015507532.1|DBSCAN-SWA
MSDAAGIRETLENHRAIDRLAAIEHDRWAHWQQYLHDQCERRDDGSLVIPAELVSRWEEQIRTPYEELAPEVQESDREQVQRYLPTVIEILAD
>NC_020990|3322761:3380877|3374346_3376998_-|WP_003949410.1|DBSCAN-SWA
MRTPARTLPIRLPPLPGEALDSWLEAIARRMDTALGDVLLHFGFPVRHRAGNQFRGIPADWTIVLDEQQTNAVAHATGTSPETVAALTLAHYDGRALHLSAGGRAVSRHVLWGRGGGSRFCPECLHATGGRWQLSWRLGFSFACTRHRRLLADCCPHCGRVPRQRPRSGRSVPRPELCGNPPTRPTRPFSAGCGTDLTRASTLLLPPGHPVLTAQDRVMEIIDGATAAFGPYRTSPQPASAVLADIRALGIRVLSDLPAAVLQEQIPADIAEAHLSTDAVSPHTGQAMERPGFMAPPRAADTAVAVTMALSILEQPGIHPAGEALRSLLEAVREELTQISATSIDSWGMGISPVLQSVHLAALAPSLRPSEYVRYRIMTETPRRPTRTTRDIEQRARKIPTMFWPPWTIRLAPPEGIHARALAPVLAALLLIPDSRTSLDQAAGLIGDVIDGTEVSRLLQEVDDLPQWPDIATALDRLADHLDATSTPIDYGRRRLLDYTGLLPHDRWLEICRRTGTPPGTGRRERIARSQLFQRLSGLPAESAPDDLGGPDSAEFRATSLRFTALQTPELVHALQHEALNFLASHHIHDEPMTWQPPATLLAGLSLPGPDPAHVDLPRLHQLVRERQHPLQHAAQVLGTTVEAIRHALDEHPAPAPPLTKSTARATGRIRQQARQAIPAERFTRLYLDEHRSLQQIATLTGFSRRVLTDLAKEYGIPLRGPQDHKRRGTIERVWLIEQYVHRRRTLPDLARETGMSPANMARWAHTHNIPLRSRGGASHSQALRAPDQAHRAPRLLRPALSGQGASERLRRFAAASAFPSLGAAASGLGLNTFTLVAQINRIERELGGPLLVRAERGRPMTLTPLGRRVLRAIRTSQDGAGS
>NC_020990|3322761:3380877|3349824_3351213_+|WP_018470266.1|DBSCAN-SWA
MTSTTPPPPPPPQPPSGGPPSGPGGHGGEPPTGGHGHSHSHGPAAPVSQHLRKVIAAVLIPFAAAVVVGLLVLWPGGAPSHERTGVGMDRQTEQGSVTKVDQVDCADVNVSQPPPNGDTSTPEGRSAQEQATGKCEKATVEVTSGPHAGRTFTEIVQPDASRKLHQGQGVVVAYAPDAPEELQYSVTDVDRKFPLALLAAIFAVAVVLVGRMRGLMALVALAASFALLTLFILPAILQGSNPLVVAVVGASAIMLIALYLCHGLTARTSVAVLGTLVSLLLIGLLGSVFIGWAALTGNTDDNTGLIHGLYPEIDMSGLLLAGVIIGSLGVLDDVTVTQTSAVWELHQADPTMGWRKLYRAGIRIGRDHIASVVNTLVLAYAGAALPLLLLFSIAQSSVGMVANSELVAEEIVRTLVGSIGLVASVPVTTALAALVVSADKGTGVPVGGAPAARGGRGRRRKR
>NC_020990|3322761:3380877|3376994_3378113_-|WP_003949409.1|DBSCAN-SWA
MNDGSVPQPGSLALSRKEDFKAFAESPRRSRPDLLTRKQLKSLPTQARADYDRQRRQWHANIGPVKTPQLTELHEDLWDIVDSNEQDGDKAKGAVAVDAFPGLGKTTSVLAFARDFHQREIEESGAFTSQGHERIPVCRVGLTGNTGMKDLNRAMLEFFGHPGQMRGTTAQFGRRVLDCVLSCDVRLVVLDDLHFLKWGQKSGIEVSNHLKWIANEFPVTLLMVGVELAKKGLFGEGTNGRDTALAQTGRRTTGLGLRPFTIDMEAGRREWRQMLLALEQRVVLTDKHPGMLADDLSDYLFARSTGHIGSLMTLINRSCQRAVRTGAERLDQELMDRVKNDEASEAARLELQAALEKKRLTSRPRPRSRRPA
>NC_020990|3322761:3380877|3369959_3372095_-|WP_003949415.1|integrase,transposase|DBSCAN-SWA
MSKAGVRVGVGTSFRYDGETVEVVEMAATTAGNEVVLKDGQGRLLRLSLKELLFSDRAAINPDGPGPSADDEGEIASVVLGQLGEAERREILERAEHVRELLTGYRSGSPELAREGEPRDEYAPSTSLEARYAAKAAELGVSSRSVRRWVTAFREKGEVGLAPSKGPTRKSQIAVDDRWVEIAVEVMVEHADQSRPSRTMVIERTRARVIARFGEGVVPQPSRATAFRLLEELERRHPLFRLSTKRNRDIAGRPEGPYGKLRPTRPGEYLLMDSTRLDVFGFDPFTLKWVQAELTVAMDWYTRCITGIRITPVSTKAGDVSAVLFQSFRPRPAGRDWPRHAVWPEHGIPRTVLVDVEGAVGPGLASPPLVPETLVVDHGKVYVSEHLTSVCRRMGISIQPARLRTGRDKGPVERYFRTSREGLLQVLPGYKGPDIHSRGESPEDDAFFFLDELEAIVREWTATVYHCRPHAGLVDPGVPGLRMSPAKMFEHGMARAGYIEVPRDRDLAFEFLQTKWRTVQHYGVEIGRRRYSGPGLPAAGLRSPYDGPVKNGWPFQVDPDDITRIYFRNPSTRQWHTLTWEHAPSARMPLSEDALVFARQLAAEKYRFPDDRLAVADLLERWNLGLGTTRAERRMVLRLSREQAAIELPPTEEETVVSLPSVRKALGQAEVAEEPVEEPRSESVEMGDDDDADLEDLAAEDDFYADALEDV
>NC_020990|3322761:3380877|3332435_3333293_+|WP_050777413.1|DBSCAN-SWA
MPRTPAAPSVPIRLIATDLDGTLLRDDKTISPRTRAALGAAERAGIGVLFVTGRPARWMEVVRDHAHADALAICGNGAAVVDLAADDESGRPRFVRVRPLLEETALQVVSRLRAHAPGTSFAVERTSGLFHEMSYPPLHLDPAQGIAPAEKLLAEPTGTAPQPVLKLLAHHHELAPDAFLTRARAILGDLASVTRSSPTALLEISAHGVSKASTLALSCAERGIRPEEVAAFGDMPNDIEMLSWAGSSYAMGNAHPDVLAAATGSTLGNNEDGVALVIERLLAGG
>NC_020990|3322761:3380877|3358698_3359202_+|WP_050777412.1|DBSCAN-SWA
MDHSQDAPQQDSSQGSSGDTLLIRRAEASDVAAIVAMLADDPLGATRESPDDLTPYLAAHTRLAADPNQHLVVAERAGKVVGTLQLTLIPGLSRRAATRSLIEGVRVHADERGSGLGTLLIEWAVETSRAEGCRLVQLTSDATREDAHRFYERLGFVASHVGFKLQL
>NC_020990|3322761:3380877|3353200_3353518_-|WP_003949433.1|DBSCAN-SWA
MKAFRLDELEAERAANDGAYLQFLRERNMSVGLYALDAGQLDPQQPHRQDEVYLVVSGRAAITVGEETTEVARGSVVYVPAGTPHKFHHISEDLRVMVVFSPPEG
>NC_020990|3322761:3380877|3342704_3343787_-|WP_003949442.1|DBSCAN-SWA
MSESTPTLRTEMAGIPTYKPGKPASASEGPAAYKLSSNENPYPPLPGVLESTLAAAAQLNRYPDMACTTLTAELAERFGVPLEHVATGTGSVGVAQQLLQATSGPGDEVIYAWRSFEAYPIITQISGAKSVQVPLTPSDVHDLDAMAAAITDRTRLIFVCNPNNPTGTVVRRAELERFLDQVPSDVLVVLDEAYREFIRDVDVPDGVELYRDRPNVAVLRTFSKAYGLAGLRVGFAIAHEPVAAALRKTAVPFGVSQLAQDAAVASLRAEDELLGRVGSLVGERARVVAALQEQGWTVPETHANFVWLRLGERTAEFAQSCERAGVVVRPFAGEGVRVTIAEAEANDLFLKAAEAFRKSG
>NC_020990|3322761:3380877|3322761_3324033_+|WP_003949456.1|tRNA|DBSCAN-SWA
MIDLRLLREDPDRVRASQRARGEDVALVDALLSADERRRSSGVRFDELRSEQKSLGKLIPKATGDEKTELLKKAGELSAAVKAADAEKDEADQEAKQLLLRLGNLVHPDVPVGGEEDFAVLAKHGTIRDFAAEGFEPRDHLELGEALGAIDVERAAKVSGSRFYYLTGVGALLELALVNAAIAQATAAGFTPMLTPALVRPRAMEGTGFLGQAAEDVYHLEKDDFYLVGTSEVPLAAYHMDEIIEADKLPLRYAGFSPCFRREAGTYGKDTRGIFRVHQFDKVEMFSYVEPEDAEAEHQRLLDWEIQWLQSLELPFQVIDVASADLGSSASRKFDCEAWIPTQGKYRELTSTSNCTEFQARRLSVRMREGKKVQPLATLNGTLCAVPRTIVAILENHQQADGSVRVPEVLRPYLGGRETLDPQ
>NC_020990|3322761:3380877|3345524_3346544_+|WP_018470269.1|DBSCAN-SWA
MRTATLRDFRVPAYVQQAGPPAATAPVDEEPPDGYTPTQRDLPVINRGDTVQVAVAPEETAPRPASEGLGPLYAVGDVHGYLDELLAALQAQGLVDADGTWSAGNARVWFLGDFTDRGPDGIGVIELVMRLSAEAAAAGGYCKALMGNHELLLLGAKRFGDTPIDSGAGTATFQAAWLLNGGQKTDMERLEDHHLQWMSRLDAIVEEDDHLLLHSDTTAYLDYGDSIEAVNDTVHSILTRNDADECWDLFRKFTKRFAFRDEGASAARELLGVYGGRRVVHGHSPIPYLLGESGSEDGSPDSGPQIDGPHVYADGLAVALDGGVTMAGKLLVSGLPLAD
>NC_020990|3322761:3380877|3372091_3372721_-|WP_003949414.1|transposase|DBSCAN-SWA
MRSACPWRTFRWYKGQKHYSGTYWSATMRNHVIYESRLELSRLLFADFDPSVRGIVAQPFLLKAVLEGKVRRHIPDYLLLTGQVPVVVDVKPLSRLSKPEVEFTFDWTRQAVESRGWKYEIWSEPPAVELENIRFLAGYRRDWLFSPEVLEELQDVDLDGVVLGQVPGCLPGRPELQVRSAVHHLLWTQTFVTDLDRPLGPSHVLRRVA
>NC_020990|3322761:3380877|3368844_3369963_-|WP_003949416.1|DBSCAN-SWA
MSTASPPGLGNLALSRKEDWKAFAETPRRIQPEQLTRRQVKALGEEARVERDRLLREWHANLGPIKTPQLAELHDDLWDIVDSNVQDGDKAKGAVAVDAFPGLGKTTSVLAFLGEFHRREIAERGAFTAAGNERLPVCRVGLTGNTGMKDLNRSLLEFFGHPGRNRGTTAQFGQRALDCVVSCEVRLLALDDLHFLKWNQKNGIEVSNHLKWIANEFPVTLVMIGVGLAGKGLFSEGDSRRDTALAQTGRRTTRLGMRPFTIESEAGRREWRQMLLALEQRVVLADKHPGMLADDLSDYLFARSTGHIGSLMTLINRGCQRAVRNGAERLSRDLLDGVKNDEASEVARKELEAALEKRQLTSRPRSRRRPAA
>NC_020990|3322761:3380877|3352781_3352997_-|WP_003949434.1|DBSCAN-SWA
MGAREVFIGLPWWVKWIAIPVLALFIFGGLIASVVGFVVGLLFKILVFVALVGGLIYVVRKFFPSSDRGSW
>NC_020990|3322761:3380877|3330878_3331334_+|WP_003949450.1|DBSCAN-SWA
MSYPHLPTTQAAVLAVREVAGHFHRTGEVTEEIGADRVSRPPAVTPSPWTAGAEELLPHEAYIELSGTPSVQVRLYADGDASVCVEGVDCPDLDRDVVPAFLASVYGGLAHLRRRAFPPSCHLVVPLPCGTEHRAYVSPLELTGWLLSRRR
>NC_020990|3322761:3380877|3373099_3373501_-|WP_003949413.1|DBSCAN-SWA
MTPTLPRTVRAVDTAQLLDLAQEAAMHGFSQRLPVDWLQEHLAAEATHYLVPTIVQHLRHRPDMPQQWRCRQLLTVRTGEQIWGLLDILPDTFDKIPETLDAASKKDIVTRLGQAVTQREWSERMSPEEMPRN
>NC_020990|3322761:3380877|3339987_3340989_-|WP_003949444.1|DBSCAN-SWA
MELHDVWFVLIAVLWTGYFFLEGFDFGVGVLTKLLARDRREKRVLINTIGPVWDGNEVWLLSAGGATFAAFPDWYATLFSGFYLPLLLILVCLIVRGVAFEYRAKRSDDRWQTNWEHAIFWCSLLPAFLWGVAFGNIVHGVAIDADKEYIGGVLDLLNPYALLGGVVTLTLFTFHGTVFVGLKTVGEIRERARKLALRLGAVTAVAALGFLLWTQADHGKTAGAVLLAVAVLALLAALGAVAKGREGWAFALSGLTIVASVAMLFVSLFPDVMPSTLDPAWSLTAANSASSPYTLKIMTWCAGIATPVVLLYQGWTYWVFRKRIGTHHIAEAH
>NC_020990|3322761:3380877|3360826_3361018_-|WP_003949424.1|DBSCAN-SWA
MSAVPDRHRNGRGPQAEVIAMTRVADIPSRRLLDAVGLREAERCGRCGADQVLYGGRGPASAG
>NC_020990|3322761:3380877|3326534_3327416_-|WP_003949453.1|DBSCAN-SWA
MTVDSTQIHNIGYRKYDGPRLGRSHARRALYSQSLRGAYGLGRSAKSKVLPMLLFAVMCLPAAIMVAVTVTAGLKTLPVDYTRYAVVMQAVIGLYVASQAPQSVSRDLRFKTVPLYFSRPVERVDYVLAKYAAMASALFLLTAVPLLVLYAGALLAELDFADQTAGFGQGMVSVALLSLLFAGIGLVVSAVTPRRGFGIAAVIAVFTITYGAVSTVQAIAFQQGNTEAVGWIGLFSPITLIDGVQTAFLGATSAYPGGAGPSTAGGAVHLLVVLGLIAGCYALLMRRYRKAGL
>NC_020990|3322761:3380877|3324893_3325613_-|WP_008416676.1|DBSCAN-SWA
MYDPTVARLTYRALLGRRRALILFVLPALLLVIAAAVRLLTGADDSTAEAVLGGFSLAVMVPIIGVVAGTGAIAPEIDDGSVVYLLAKPIKRPTIILTKLFVAIGVTMAFSAIPTLLAGFILNGNGGQLAVAYTVAALVASIAYAALFLLLGTVTRHAVVFGLVYALIWEGLFASLISGARTLSVQQWALAVAEKVTGGEAVTSDVALPTAVILLVAATVLATWYAGQKLRSLTVAGEE
>NC_020990|3322761:3380877|3346752_3347670_+|WP_003949439.1|DBSCAN-SWA
MHMNSAPHLLNEDRAAYERLLDEALRTITHDEGHQRATPPGRLPVAELRRLALGGTAAITAAAATEYRHLLSLREELGETTTAGGATGDDPAPAPGGTGLTTAVSQMTEATGAGALAVLAVLAPLLAGTAALIFLLVGYGLRMLDPAPALAQTLLTTGWVFAAFAAAALLAAGLALLLTALRNKALFPAAPVPADPLRREVQQAADAWERALTERGILPFLRTTLAEAAASGLEPRPGKAVEPAGSTPADEADRMPQLGYGRPGFSSPSESGQDRPAPDSRPSYQSPQFSSPDFSGPDFDGPGHG
>NC_020990|3322761:3380877|3341003_3342512_-|WP_003949443.1|DBSCAN-SWA
MDLALAPETLSRWQFGITTVYHFLFVPLTISLAGLTAGLQTAWVRTGKEKYLKATKFWGKLFLINIALGVVTGIVQEFQFGMNWSDYSRFVGDVFGAPLAFEALIAFFFESTFIGLWIFGWDKLPPKIHLACIWMVSIGTILSAYFILAANSWMQHPVGYRIDEVTGRAELTDFWLVLTQNTALAQFFHTMAAAVLTGGAFMAGIAAYHLMRKKHIDSMRLSLRLGLVTLAVGGLLTAVSGDTLGKIMYQQQPMKMSAAEALWEGEEPAPFSLFAVGDVDKGHNVVTVEVPGLLSFLAHNNFTDRVPGINELNAQYQEKYGPGDYRPNIPVAYWGFRWMIGFGMTSFGIGLLGLWLTRRKFLLPHRLRTGEDEVPNLVLTRTKLLSPRLSRLYWRLTLWTLAFPLIASSWGWIFTETGRQPWAVYGVLRTADSVSPGVSQGEVLTSMIVFTLLYAVLAVIEVRLLVKYVKAGPPELTEADLNPPKKIGGDPSDADRPMAFSY
>NC_020990|3322761:3380877|3378109_3380236_-|WP_003949408.1|integrase,transposase|DBSCAN-SWA
MSRAGARVGVGTRFRYDGESVEVVEMAATTAGNEVVLKDGRGRLLRLSLKELLFSDRAAVSPDGPGPSADDEEEIASVVLGQLDSSARAKVLERAEHVREVLTGYRSGAPELARDGEPRPDYRPERPWEARYTAKAAELGVSPRAVKQWVSDFRRGGEAGLAPKKTTERPHSGVDDRWVETAVEVMVEHTDQSRPSRTMVIERTRARVIARFGEGVVRQPSRATAFRLLEELERRHPLFRLSTKRNRDIAGRPEGPYGKLRPTRPGEYLLMDSTRLDVFAFDPLTLKWVQAELSVGMDWYSRCITGIRLTPVSTKAVDVSAVLFQSFRPRLAGRDWPRHAVWPEHGIPRTVLVDVEGATGPGLASPPLVPETLVVDHGKVYVSEHLTSVCRRMGISIQPARLRTGRDKGPVERYFRTLREGLLQVLPGYKGPDIHSRGESPEDDAFFFLDELEAIIREWTAAVYHCRPHSSLVDPGLPGLRMSPAKMFEHGMARAGYIEAPRDRDLAYEFLQTKWRTVQHYGVEIGRRRYSGPGLPEPGVRSPYDSPVKNGWPFQVDPDDITRIYFRDPATRAWRTLVWEHAPSAEMPLSEDALTFARQLAASKYRFPDDRLAVADLLERWNLGLGTTIAERRMALRLSREQAAIELPESEAETVVSLPSVCKALGQDEQTAELREPDVVTETGDDDEADLEDLAGEDDFYADALEDV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003949456.1|3322761_3324033_+|tRNA	serine--tRNA ligase	A0A2K9L088	Tupanvirus	1.2e-69	36.3
WP_003949455.1|3324059_3324884_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_008416676.1|3324893_3325613_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_015507520.1|3325626_3326538_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.5e-13	30.5
WP_003949453.1|3326534_3327416_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_003949452.1|3327412_3328438_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.1e-19	29.5
WP_015507521.1|3328734_3330552_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_003949450.1|3330878_3331334_+	hypothetical protein	NA	NA	NA	NA
WP_010644320.1|3331344_3332247_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_050777413.1|3332435_3333293_+	HAD family phosphatase	NA	NA	NA	NA
WP_003949447.1|3333295_3334342_-	M23 family metallopeptidase	A0A1B0XUH3	Freshwater_phage	2.4e-18	40.0
WP_003949446.1|3334465_3336181_-	GAF domain-containing protein	NA	NA	NA	NA
WP_003949445.1|3336258_3339924_-	thiol reductant ABC exporter subunit CydD	W8CYL7	Bacillus_phage	7.5e-19	25.7
3338061:3338084	attL	NA	NA	NA	NA
WP_003949444.1|3339987_3340989_-	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_003949443.1|3341003_3342512_-	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_003949442.1|3342704_3343787_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	3.8e-11	24.7
WP_003949441.1|3344172_3345294_+	LacI family transcriptional regulator	NA	NA	NA	NA
WP_018470269.1|3345524_3346544_+	Ser/Thr protein kinase	NA	NA	NA	NA
WP_003949439.1|3346752_3347670_+	hypothetical protein	NA	NA	NA	NA
WP_003949438.1|3347809_3349603_-	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_018470266.1|3349824_3351213_+	YibE/F family protein	NA	NA	NA	NA
WP_015507526.1|3351257_3351668_-	SsgA family sporulation/cell division regulator	NA	NA	NA	NA
WP_003949435.1|3351792_3352611_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003949434.1|3352781_3352997_-	DUF5326 family protein	NA	NA	NA	NA
WP_003949433.1|3353200_3353518_-	cupin domain-containing protein	NA	NA	NA	NA
WP_003949432.1|3353635_3354016_+|holin	phage holin family protein	NA	NA	NA	NA
WP_015507527.1|3354195_3355320_+	cystathionine gamma-lyase	NA	NA	NA	NA
WP_003949430.1|3355523_3356429_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003949429.1|3356475_3356958_+	NUDIX hydrolase	NA	NA	NA	NA
WP_003949428.1|3357158_3358037_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003949427.1|3358189_3358648_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_050777412.1|3358698_3359202_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_015507529.1|3359358_3360762_-	serine hydrolase	A0A2P1JQM9	Mycobacterium_phage	1.6e-14	31.4
WP_003949424.1|3360826_3361018_-	hypothetical protein	NA	NA	NA	NA
WP_003949422.1|3361927_3362470_-	transferase	NA	NA	NA	NA
WP_003949421.1|3362626_3363196_+	deaminase	NA	NA	NA	NA
WP_003949000.1|3363570_3364341_+|transposase	IS5-like element IS112 family transposase	NA	NA	NA	NA
WP_003949420.1|3364496_3364868_+	TIR domain-containing protein	NA	NA	NA	NA
WP_003949419.1|3364878_3365859_+	caspase family protein	NA	NA	NA	NA
WP_015507532.1|3365858_3366140_+	hypothetical protein	NA	NA	NA	NA
WP_015507533.1|3366103_3368848_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003949416.1|3368844_3369963_-	AAA family ATPase	NA	NA	NA	NA
WP_003949415.1|3369959_3372095_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_003949414.1|3372091_3372721_-|transposase	TnsA-like heteromeric transposase endonuclease subunit	NA	NA	NA	NA
WP_003949413.1|3373099_3373501_-	hypothetical protein	NA	NA	NA	NA
WP_015507536.1|3373555_3373858_-	hypothetical protein	NA	NA	NA	NA
WP_015507537.1|3373958_3374336_+	hypothetical protein	NA	NA	NA	NA
WP_003949410.1|3374346_3376998_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003949409.1|3376994_3378113_-	AAA family ATPase	NA	NA	NA	NA
WP_003949408.1|3378109_3380236_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_101277829.1|3380232_3380877_-|transposase	TnsA-like heteromeric transposase endonuclease subunit	NA	NA	NA	NA
3384468:3384491	attR	NA	NA	NA	NA