CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_021084	Wolbachia endosymbiont of Drosophila simulans wNo, complete sequence	3 crisprs	cas3,RT,DEDDh,PD-DExK	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_021084_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021084_1

119993-120537

Orphan

Consensus_repeat	Method
ATTTCGAGATAGTTAACGCTCTATTAGAAAATGGAATTGATATTAATGT	CRISPRCasFinder

5 spacers

The CRISPR arrays of NC_021084_1

>merge|NC_021084|1|119993-120537|CRISPRCasFinder
ACTTAAAGATAGTTAGGGCTCTATTAGAAAAAGGAATTGATGTTAATATAGAAGGCACTTTCAACGAGACTCCCTTACACGGGGCTGCTCGCGTTGATAATTTCGAGATAGTTAAAGCTCTATTAGAAAATGGAGCTAACGTTAATGCTAAGGGTGATTTTGGTTATACTCCTCTGCATTTAGCTGTAGAACATGATCATTTAGAGATAGTTAAATATCTTATAGAAAATAAAGCTGATATTAATGCTAAGAGTAATTTTAGTTATACTCCTCTGCATTTAGCTGTAAAGCATGGTCATTTAGAGATAGTTAAATATCTTGTAGAAAATAAAGCTGATATTAATGTAAAAGATAAGTCTAACACTACTCCCTTATACTACGCTGATGCGAGTGGTCATTTAGAGACATTAAACGCTATATTAAAAAATATAGCTGATATTAATGCAAAAGACCATTATGACAACACTCTCCTACACACAGCTGCTTCCGATGGTAAATTAAGAATGGTTGAAGCTCTATTAGAAAATGGAGCTGATATTAATGCT

>NC_021084|1|1|119993-120537|CRISPRCasFinder
ACTTAAAGATAGTTAGGGCTCTATTAGAAAAAGGAATTGATGTTAATAT	AGAAGGCACTTTCAACGAGACTCCCTTACACGGGGCTGCTCGCGTTGATA
ATTTCGAGATAGTTAAAGCTCTATTAGAAAATGGAGCTAACGTTAATGC	TAAGGGTGATTTTGGTTATACTCCTCTGCATTTAGCTGTAGAACATGATC
ATTTAGAGATAGTTAAATATCTTATAGAAAATAAAGCTGATATTAATGC	TAAGAGTAATTTTAGTTATACTCCTCTGCATTTAGCTGTAAAGCATGGTC
ATTTAGAGATAGTTAAATATCTTGTAGAAAATAAAGCTGATATTAATGT	AAAAGATAAGTCTAACACTACTCCCTTATACTACGCTGATGCGAGTGGTC
ATTTAGAGACATTAAACGCTATATTAAAAAATATAGCTGATATTAATGC	AAAAGACCATTATGACAACACTCTCCTACACACAGCTGCTTCCGATGGTA
AATTAAGAATGGTTGAAGCTCTATTAGAAAATGGAGCTGATATTAATGCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021084.1\|WP_015587731.1\|125510_126212_-\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NC_021084.1\|WP_015587732.1\|126380_127547_-\|phage-tail-protein	unknown	unknown	gnl\|CDD\|370616
NC_021084.1\|WP_015587737.1\|130126_130639_-\|phage-tail-protein	unknown	unknown	gnl\|CDD\|284235
NC_021084.1\|WP_081600831.1\|110737_110941_+\|hypothetical-protein	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|238828
NC_021084.1\|WP_015587721.1\|106487_107183_+\|di-trans,poly-cis-decaprenylcistransferase	unknown	unknown	gnl\|CDD\|376506
NC_021084.1\|WP_041581447.1\|129650_130127_-\|hypothetical-protein	unknown	unknown	unknown
NC_021084.1\|WP_015587735.1\|129199_129664_-\|phage-baseplate-assembly-protein-V	unknown	unknown	gnl\|CDD\|368076
NC_021084.1\|WP_015587722.1\|107172_107799_+\|phosphatidate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|366491
NC_021084.1\|WP_015587733.1\|127810_128602_-\|baseplate-J/gp47-family-protein	unknown	unknown	gnl\|CDD\|164963
NC_021084.1\|WP_015587734.1\|128941_129196_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|269821
NC_021084.1\|WP_015587726.1\|111975_119118_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|293786
NC_021084.1\|WP_015587720.1\|104955_106182_+\|hypothetical-protein	unknown	unknown	unknown
NC_021084.1\|WP_051063868.1\|110551_110731_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238828
NC_021084.1\|WP_015587730.1\|125014_125479_-\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NC_021084.1\|WP_015587723.1\|107813_108023_-\|zinc-finger-domain-containing-protein	unknown	unknown	gnl\|CDD\|370944
NC_021084.1\|WP_015587728.1\|123088_124582_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|214861
NC_021084.1\|WP_015587729.1\|124575_125010_-\|DUF2924-domain-containing-protein	unknown	unknown	gnl\|CDD\|371394
NC_021084.1\|WP_081600809.1\|111035_111584_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369847
NC_021084.1\|WP_015587725.1\|108808_109747_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|153216
NC_021084.1\|WP_015587724.1\|108094_108601_-\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234674

Protein	Function_ID	Function_description	E-value
NC_021084.1\|WP_015587731.1\|125510_126212_-\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	6.56357e-30
NC_021084.1\|WP_015587732.1\|126380_127547_-\|phage-tail-protein	gnl\|CDD\|370616	pfam09684, Tail_P2_I, Phage tail protein (Tail_P2_I). These sequences represent the family of phage P2 protein I and related tail proteins from a number of temperate phage of Gram-negative bacteria.	5.25232e-06
NC_021084.1\|WP_015587737.1\|130126_130639_-\|phage-tail-protein	gnl\|CDD\|284235	pfam06763, Minor_tail_Z, Prophage minor tail protein Z (GPZ). This family consists of several prophage minor tail protein Z like sequences from Escherichia coli, Salmonella typhimurium and Lambda-like bacteriophages.	3.75958e-09
NC_021084.1\|WP_081600831.1\|110737_110941_+\|hypothetical-protein	gnl\|CDD\|238828	cd01651, RT_G2_intron, RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable element with both gag-like and pol-like genes. This subfamily of proteins appears to have captured the RT sequences from transposable elements, which lack long terminal repeats (LTRs).	5.0045e-15
NC_021084.1\|WP_015587721.1\|106487_107183_+\|di-trans,poly-cis-decaprenylcistransferase	gnl\|CDD\|376506	pfam01255, Prenyltransf, Putative undecaprenyl diphosphate synthase. Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.	1.83394e-110
NC_021084.1\|WP_015587735.1\|129199_129664_-\|phage-baseplate-assembly-protein-V	gnl\|CDD\|368076	pfam04717, Phage_base_V, Type VI secretion system, phage-baseplate injector. Family of bacterial and phage baseplate assembly proteins responsible for forming the small spike at the end of the tail or bacterial pathogenic needle-shaft.	8.32608e-47
NC_021084.1\|WP_015587722.1\|107172_107799_+\|phosphatidate-cytidylyltransferase	gnl\|CDD\|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	1.39212e-36
NC_021084.1\|WP_015587733.1\|127810_128602_-\|baseplate-J/gp47-family-protein	gnl\|CDD\|164963	PHA02568, J, baseplate assembly protein; Provisional.	2.54538e-58
NC_021084.1\|WP_015587734.1\|128941_129196_-\|hypothetical-protein	gnl\|CDD\|269821	cd14671, PAAR_like, proline-alanine-alanine-arginine (PAAR) repeat superfamily. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat superfamily, where it forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). The T6SS is responsible for translocation of a wide variety of toxic effector molecules, allowing predatory cells to kill prokaryotic as well as eukaryotic prey cells. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. The PAAR-repeat proteins form a diverse superfamily with several subgroups extended both N- and C-terminally by domains with various predicted functions; the termini are exposed to solution, and do not distort the VgrG binding site. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes. It has been shown that PAAR proteins are essential for T6SS-mediated secretion and target cell killing by Vibrio cholerae (encodes two PAAR proteins) and Acinetobacter baylyi (encodes three PAAR proteins); inactivation of all these PAAR genes results in inactivation of Hcp secretion as well as T6SS-dependent killing of E. coli.	3.58704e-13
NC_021084.1\|WP_015587726.1\|111975_119118_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	2.72884e-21
NC_021084.1\|WP_051063868.1\|110551_110731_+\|hypothetical-protein	gnl\|CDD\|238828	cd01651, RT_G2_intron, RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable element with both gag-like and pol-like genes. This subfamily of proteins appears to have captured the RT sequences from transposable elements, which lack long terminal repeats (LTRs).	4.80862e-10
NC_021084.1\|WP_015587730.1\|125014_125479_-\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	1.41592e-23
NC_021084.1\|WP_015587723.1\|107813_108023_-\|zinc-finger-domain-containing-protein	gnl\|CDD\|370944	pfam10276, zf-CHCC, Zinc-finger domain. This is a short zinc-finger domain conserved from fungi to humans. It is Cx8Hx14Cx2C.	4.81874e-05
NC_021084.1\|WP_015587728.1\|123088_124582_-\|recombinase-family-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	4.32019e-40
NC_021084.1\|WP_015587729.1\|124575_125010_-\|DUF2924-domain-containing-protein	gnl\|CDD\|371394	pfam11149, DUF2924, Protein of unknown function (DUF2924). This bacterial family of proteins has no known function.	3.52664e-36
NC_021084.1\|WP_081600809.1\|111035_111584_+\|hypothetical-protein	gnl\|CDD\|369847	pfam08388, GIIM, Group II intron, maturase-specific domain. This region is found mainly in various bacterial and archaeal species, but a few members of this family are expressed by fungal and chlamydomonal species. It has been implicated in the binding of intron RNA during reverse transcription and splicing.	1.3277e-13
NC_021084.1\|WP_015587725.1\|108808_109747_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl\|CDD\|153216	cd01745, GATase1_2, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	0.00178743
NC_021084.1\|WP_015587724.1\|108094_108601_-\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	8.0375e-86

>NC_021084.1|WP_015587726.1|111975_119118_-|tetratricopeptide-repeat-protein
MPKVNIDPQSVKLQKEEKSLQLKNRIKRQYNPSDINIAKLFLAIREHRTGNPQLNKISEIEGLLTQVQNINDIDLNDIGNTPLHVAVSKKHPDIVEFLLNVPGIDPNIQNNQGDTSLHIAVSEDDEELVRLLLSKKAEMNIKNKDGKTPLDIARSNTQPNKEKIISTLEEHLNKSSNQVERLSEQEKEVHEKLRRFVEDFVFIYEGSLSEYYERLENQKGKPGKWADFINRVTRTGKSGTEQGERESKVIPLIGISVLQEAISGIGSYYNREELKKLIDQLYIFEKDPVKVREELVKSGIEIFQAFESQFVQVKADGSWQRAMAKLAKDAVSRVVDYYRQNNAKEFCAFSITEGIILGESKKYKQTSIGVPHIKSGHTLESKNLNSWNTAELFDKAGLVTIKSDGSADKYYRKRDGKSDTSKYGYRLLFKWELENKIKKFVREYSEEKPPREEYRYILKSDEEKWEGKLLDELNKQDPKLVEERLLSNFKEEMKQEAEKKVNELEDYIGKNFNELSSYIESNQNEIKRVLDELISQHQQASQEIADSIAEERKESRESFEKVDKKLDEIHSLIIAGQQVREPIWFDVKKPVSLFTGREEELIDLHNKVQRSSEKITILSQITSISGLGGIGKTELAREYIQEYSKDYYNDVIWINAESEVSIIESFTRLAKDKLKIDTKDANGKKKDIQAIVEEVYEFFSDSKSLFIFDDAEKSNYLNKFLPLHDLLTVGNEPYILITSRNQEWDRGIEVINLNELKSEEAIEFVKKSLSIEDESQNEKIKALVEKLQRFPLAIQQAIAYIEDQRITEEFDIDDYLEKYEKKTKDLLDSEVFMGIDNDYAKTTFSTWKITTNKIASDRENGKLALRVLNIISYLAPERISREVFLGLTGSSEEELRSAVRLLIKYSMVNGEQKQSVLSTHKLVQEVTRIVLEEEGKGKEVMDEVFKLLRASFPYGSDKLEDYVKKREFLPHLEAFLLHVDNWLKKNPKDKQKIEEDYLEGLLILISDGYFSLGNPKRQKDLLERALHILEKHYGVEHFEIGMILENLGIAYLILGDYQKAKDLTEKALPILESHYGEDHFEVAKTLLNLSISYGALGNYQKQKELLKRALPIFKKHYGEDHPEVAIVLENLATADRALGNDQRAKESLEMADKIYQKGEVAECLPNTSSGMRKREAKIGECELSWEDVDKFNTEEDAKRDFSKIKIDSEKFLHYIKDLPEDKRYQLIEIANKVEVTGGFRDLINKLSNNQKVMNHLNRVKKISSITMHGMMAKNVLADFLNGDYQGVAINVGFIAGGQGFARVAEVASREGLNLLSEGKALLGRSLRAASPFLARGTSAFIAYDLVNQVKAFKNGTEGALVGVVGDSIYLSVDAAEIGIEVAESFAILEGVSSVTGPIGSGIGAVVFVGTDVYMAVKKVDKIDQIIHLTGKEKFIEGLRAFIGMQPEQYIEELMEGKQLYNQLVKQGFEYLKEHSNIQSYVFPTSKSSVDSCRKVPYQQNICNMARFSILCLRKVNVTFYAEKCTTKFEIDLDSTVLLDRKRTDIRWSRARPDNPSGGKLFCFSQGNDEPAPSYGSYLCENAIGLSNNKIEGYTLIDLGEGKDYARGFKDSQNIFVVNDGSKEYYGGNKNDIFILQGDLIGGSLYGEGGIDTLDLTGFAHGVVTVDVYLNANIGITVYKHHGYHSFKINSVERVFGRKVEGDHIFSACETKFVDGNGGAEDQLDYVQIENNDCVYDIQVIIKPYTEIDNMALKGNFSYILPSQNGSASVKLLTNLESNHRFTFGYVLADVQSIDVEDQNSIRFNFFSKVINSNFSISISYNIMNNIIYQLKDSAEIKVGKERNLYAIQSTNKTIDEIIESYPAIANKLNMTIAVQSVNEYILVGHEKCEVLQNNPIHNSHLIKNGGENIYVITIASGKQRYDHSIFSIPEVNIYNLDKGSSIDTLDLRKVIKIIQQDDLRVHIGLPRIYQDGNDLLVKLEAEFGQSFPAEVLMVRLKDGLNWYEKLHIISNNIPMKISSELELKPLPLIFEKDKEIIVVTGQDVEEGTELIISRKGENYRFVRSNDNDLMITNAFDSTITRDDFCSITLSEFYKTPKMKTLSIKFADKGIVLRDHEKEINAARNVDSVKREYKDQVYNDVFSKYKQQNVAIRHRRHKEYSDLDKRFSENIRNSSTKASSWINDLFGWVKNSIGRFRAALPEILANYSNTAGTSQFSSEVCISNNVGLGFLLLQSFLDRKYPLPKFCSATHEEVLADTLDIMEEFKKTLKKTAKQSGVSVKGFDFFKVYSDIAGHVRNERYSKIPSTLYSAVKEAYPKNEKFLSTFKSSIGKMLDRQKMVNNHNQEQGIANVDPSFLLNRIVVESVNNGGLKGVNCAGQVA
>NC_021084.1|WP_081600809.1|111035_111584_+|hypothetical-protein
MRRAPQERVIKDLNPINRGWSQYYSSVVSCKIFSSLDNIMHRKFWKWAVFRHPNKGRCWIKRRYFKKYNNENWRFMTSNKVRLTIHSDHVIKRHIKVQKTRSPYDGDWVYWGNRLNRILDKSPKVIKLLKLQQSKCDQCQLWFKSDDILEIHHRDQNRKNNMIKNLSLLHGHCHDELHRRCA
>NC_021084.1|WP_081600831.1|110737_110941_+|hypothetical-protein
MSVIFYCDDFVIIHENEEIILKAKILVEEWLETIGLKLKPSKTRVSHTLRTIDETKPGFDFLGFSIR
>NC_021084.1|WP_051063868.1|110551_110731_+|hypothetical-protein
MEDGKLQSTKRGTIKGGTISPLLACVALHGLEQHVKKALTNELFQCMKRKYGKIPHKNA
>NC_021084.1|WP_015587725.1|108808_109747_+|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MHKCYNRVFNILLITFLLLSNIAYSEKVNKELSALTAENAVNYNIIVGLLQTDESQNIYEIFNNFGVKTIFIDYDKIINLKEIQEEFAKQDEILAKKLILDRIKAEVAKFIKEQKINRIFISDNFHSALNPYRQLVNEAIVKIVDDNPTIHLLAICGGLQDIMHAKEIEITNVVNDEKNHLKSASYPQKENMPLQQIKIVPGSRLEKVVARFLLPNQNGWFSTYFPNAHSGTVSNTTENRRRLELLGYKIAAFANDGVIEAIEDKHGNIYFQSHLEALVVKSDKNSRLSSQKVRQVSTLVAIAIINDFLHRV
>NC_021084.1|WP_015587724.1|108094_108601_-|pantetheine-phosphate-adenylyltransferase
MNINNKIGIYPGTFDPITFGHLDIIKRACKLVDKLIVGVAENVNKHTTFNIKLRTSMAENEVKGAEINADVISFNGLLVKFAKEQNASVIIRGLRAVSDFDYEFQMSWVNYKLSHEIETIFLPASEDTQFISSSFVKEIARLGEDVSSFVSQNVQTELINLNRVKNGE
>NC_021084.1|WP_015587723.1|107813_108023_-|zinc-finger-domain-containing-protein
MSEVRDNNLIVCCRGDENDDGSGHPVVYLHKEGEMYCPYCSKPMSEIVNSEEFQSVEVKAVNKKERTKG
>NC_021084.1|WP_015587722.1|107172_107799_+|phosphatidate-cytidylyltransferase
MVDNNFMVRTLSSIVILLIFSFATYFSDLSFYLLIFSIAVLSSFEWYNLTQGNRILYIFALLLIALPNASLIYLYNLPQGKYELIWLILTIWSIDITAYLFGKNFGGAKICPIISPGKTWSGLLGAVLAGVFCTIFGSIFLSLFPIFYSPIIGFTIAILAQLGDFTESLIKRVYNVKDSGGIIPGHGGVLDRMDSLIFTAPFIAIYIS
>NC_021084.1|WP_015587721.1|106487_107183_+|di-trans,poly-cis-decaprenylcistransferase
MLNLESLPKHLAIIMDGNGRWAKNQGMVKIDGYRKGSEVAFDIAKHCTTLAISYLTLYAFSMENWLRSENETDYLFNLFYSTLINEDKMKFIYNCNIKLNFIGNLSLLPSKIFDQIKKAEEVTHKNDGLLLTVAVSYGAKQEIIHAINNVIKGNIDCVLEEEFEKFLYTKDLPKLDLLIRTGGEKRLSNFLLWQAAYAELYFCDTLWPDFSCQDLSKALADYTKREKKYGR
>NC_021084.1|WP_015587720.1|104955_106182_+|hypothetical-protein
MDFDKADNAEDLDNKKLQLICKAYDIRLRSSQRVVDGINSMNYSKLEILCKYNNKFSYKGIEELLSDESIVNHINDYDDEMFSSMLNDAPSERNILEILKGEEVCNTNNEFESSGNEKNEEDYGYYDNFDYEEDEKNDPNNFAKEALGNKGINEKRVDDVQFYNDADVEIPPKNQNDIRNIRLIQWMIVESDGKLSEQNVTELLKDQSSIDRINSIGDKKLQLILKSNKFSGENIMELLGNQKVVEYLCFIDYEKFELIHNSDKFNSSNYTSSSYKIIRLLENQQVVEHINFIDYEKLKFILCNDKLLFSDIVRLLKNQEVVENIISFNIKKFRLIFYRDNLNYVDTIELLRNQEVVNRIGFTPFEELKSMCSHSSLSDIIKLLEDKNGPSNVLSGTRKEKMQVSYIS
>NC_021084.1|WP_015587728.1|123088_124582_-|recombinase-family-protein
MLKEVRCAIYTRKSNEDGLEQKFNSLDAQRVACEKYIKSREGWVALAKRYDDGGFSGKNLERPAIKELFEDVKGGEVDCVIVYTLDRLSRETKDSIEVTSFFRRHRVNFIAVTQIFDNNTPMGKFVQTVLSGAAQLEREMIVERVKNKIATSKEQGLWMGGTLPLGYDVKDKELIINEKEAKIVGHIFERYLELKSMAELARELNREGYRTKSDIFKKATVRRIITNPIYMGKIRHYEKEYEGKHEAIIEEEKWQKAQELIKNQPYRKVKYEEALLRGIIKCKSCDVNMTLMYAKKENKRYRYYVCNNHLRGKNCESVNRTIVAGEVKKEVMRETEKLYEKWEEKAEEWKNLSFGKQKEVVKKLIKGVMVKEDGIEVHSESEEKFIPIKKKGNKCTVVEPEGKTNNALLKAVVRAHLWKRQLEEGKYRSVKELSAKINIGTRRIQQILRLNYLAPKIKEDIINGRQPRNLKLVDLREIPMLWSEQLEKFYRFKQAVC
>NC_021084.1|WP_015587729.1|124575_125010_-|DUF2924-domain-containing-protein
MEKEIEKKVMNLEKKALVELRRIWKKVFGEEAPRYSKKYLIPRLAYRMQEKAYGEMSRKGTKRLEYLADRLEKGKRISSDKLPVEGTELILERGEETHAVMVTDKGLIYREEFFTSLSAVAGKIMGMSYNGPLLFGMRDKEKEC
>NC_021084.1|WP_015587730.1|125014_125479_-|ankyrin-repeat-domain-containing-protein
MLKFGKFNKSAEELLENSHENIYARDEKELHYAVDAKTVKLLVEKGANVNAADARGYTALHLAVTEKRLETVRELIKSGGNVNAEEYGSKCTPLHLACMIGEKEIVKELVKAGGEIEQADKFGMTAMDYAKNSKEITEILKKEIDRIEKLFMKG
>NC_021084.1|WP_015587731.1|125510_126212_-|ankyrin-repeat-domain-containing-protein
MSFSKSKFFKEVSSKDINKRNEEGETILHQAVEISDYKTVRFLIKKGAEVNARDKNGYTPLHCAVFAKSLENVKVLLRSGAEVNATQYVTGCTPLHSACKMGGAGVEIIKELVKAGAEVNQLNKYGATPMYYIWESEKYSLCDSKESEKASKFLREKGGVIKNRELTCYGIERLVGEIADMLNGSYLPELKIIEIEEIRKRDKSLIKEECQNLASKIISKVNEMIDEVVRRKA
>NC_021084.1|WP_015587732.1|126380_127547_-|phage-tail-protein
MKSLLRPNSTKQEQALVDATDYKVDPSCIRGFKFSLKEETLPWLIEEYELGEILRWVKDKRRAIVEGVKFQRLRGTPASLKIALKWANIEDITIIEEPPGKHFFELQVGIKEVPNDFFVDAVVELAKLSLPVRSRLMRIFNDYYNVQRFILDESLFGDLLSDYSGVKIEKDGPVLSFGRVNFFRSSGPVIRIIENYLRDHYERALSNDIYRLDVAILGETEPHTRDYKGIYERDHLWYNLKALYPLPQSLLPSIKFAKAQIVLSDSWKLGEINSCFPVGRIEEEGNKFVLGNDKLSGQHWSLKHKPILERFSIIHRYKVENYTDQKVRKYVLAEHNIYYKNDLYSEQKDSIHELEKHILVFYPGVLKWHEHRHLHRSWKNSQVICVIS
>NC_021084.1|WP_015587733.1|127810_128602_-|baseplate-J/gp47-family-protein
MEQPNIIEPLNFEEILSRMREELVKRDASFTALVESDPAIKILEVAAWRELLLRQRINEAVKGNLLKFATGEDLDSLAEFYGVERQNEEDDERFRKRIKAKIKGWSTGGNYRYHALSADSRVKDALVESTIPGKVQISILSTQLSTTGIVSEELLEIVKKQVTRDYIRVLTDTVTVIGCNITEIDIHSRMSISPIISEEEIKKQFIKKFEESRRLGWSVTRSWIIANLFVEGVENVELIEPKEDVVVLGNECAVLGHVKLDRI
>NC_021084.1|WP_015587734.1|128941_129196_-|hypothetical-protein
MGKAIVCVGDNCTGIPVHVCMSGSEDVFVNSRSVCRRGDILTIGETLTQGSNSVFVNGMGVTRTGDLVSCSFKVIGVSKNVFAE
>NC_021084.1|WP_015587735.1|129199_129664_-|phage-baseplate-assembly-protein-V
MLENNFAISELQRKMANIVRIGVVKEIDYEKAKVRVKIGEFLTDYLPWITSKAGKDRDWSPPDIGEQVMIFSPLGELSLGVVLGGIYQEKYPAPENKKEVSSLTFQDGTKLSYDKDKHHLEIEVVDKITLKAGESGIEMTKERIKLKGRRIDLN
>NC_021084.1|WP_041581447.1|129650_130127_-|hypothetical-protein
MNWKDLHNAICTTLKKEISAIQTCEIYPSIRKELLAPAVFIELSSLEQGKDPGTEELALRAKFEARIVIDSTIENASLIVRTLAAEVAKVVNKNTWNVKNVSPGEFISGGGDDFRPELDAYLVWMVEWVHTIHVGRSIWKEGKFMPHKIEIGEINVRK
>NC_021084.1|WP_015587737.1|130126_130639_-|phage-tail-protein
MFNIKTSNNINEIISNIDGKEQKVKLAAIKALNRTALWLKLKTAKEISEEKKIKLSLIRKRLRIFKAKTSRLEVLIRANLYDIRASTIGKIQKTRRGSKVGKHEFIGGFAAVMPKGNSGMFKREGRAALPIKEVKLPLEPEASRIIENLVNYEVEKVFTKFFKRELSCRV

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Crispr_ID: NC_021084_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021084_2

120686-120833

Orphan

Consensus_repeat	Method
ATTTCGAGATAGTTAACGCTCTATTAGAAAATGGAATTGATATTAATGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021084_2

>merge|NC_021084|2|120686-120833|CRISPRCasFinder
ATTTCGAGATAGTTAACGCTCTATTAGAAAATGGAATTGATATTAATGTGCAAAACAATAATGGCGATACTCCCTTACACGAGGCTGCTTGCGCTTGTAATTTCGAGATAGTTAACGCTCTATTAGAAAATGGAATTGATATTAATGT

>NC_021084|2|2|120686-120833|CRISPRCasFinder
ATTTCGAGATAGTTAACGCTCTATTAGAAAATGGAATTGATATTAATGT	GCAAAACAATAATGGCGATACTCCCTTACACGAGGCTGCTTGCGCTTGTA
ATTTCGAGATAGTTAACGCTCTATTAGAAAATGGAATTGATATTAATGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021084.1\|WP_015587731.1\|125510_126212_-\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NC_021084.1\|WP_015587732.1\|126380_127547_-\|phage-tail-protein	unknown	unknown	gnl\|CDD\|370616
NC_021084.1\|WP_015587737.1\|130126_130639_-\|phage-tail-protein	unknown	unknown	gnl\|CDD\|284235
NC_021084.1\|WP_081600831.1\|110737_110941_+\|hypothetical-protein	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|238828
NC_021084.1\|WP_015587721.1\|106487_107183_+\|di-trans,poly-cis-decaprenylcistransferase	unknown	unknown	gnl\|CDD\|376506
NC_021084.1\|WP_041581447.1\|129650_130127_-\|hypothetical-protein	unknown	unknown	unknown
NC_021084.1\|WP_015587735.1\|129199_129664_-\|phage-baseplate-assembly-protein-V	unknown	unknown	gnl\|CDD\|368076
NC_021084.1\|WP_015587722.1\|107172_107799_+\|phosphatidate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|366491
NC_021084.1\|WP_015587733.1\|127810_128602_-\|baseplate-J/gp47-family-protein	unknown	unknown	gnl\|CDD\|164963
NC_021084.1\|WP_015587734.1\|128941_129196_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|269821
NC_021084.1\|WP_015587726.1\|111975_119118_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|293786
NC_021084.1\|WP_015587720.1\|104955_106182_+\|hypothetical-protein	unknown	unknown	unknown
NC_021084.1\|WP_051063868.1\|110551_110731_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238828
NC_021084.1\|WP_015587730.1\|125014_125479_-\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NC_021084.1\|WP_015587723.1\|107813_108023_-\|zinc-finger-domain-containing-protein	unknown	unknown	gnl\|CDD\|370944
NC_021084.1\|WP_015587728.1\|123088_124582_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|214861
NC_021084.1\|WP_015587729.1\|124575_125010_-\|DUF2924-domain-containing-protein	unknown	unknown	gnl\|CDD\|371394
NC_021084.1\|WP_081600809.1\|111035_111584_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369847
NC_021084.1\|WP_015587725.1\|108808_109747_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|153216
NC_021084.1\|WP_015587724.1\|108094_108601_-\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234674

Protein	Function_ID	Function_description	E-value
NC_021084.1\|WP_015587731.1\|125510_126212_-\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	6.56357e-30
NC_021084.1\|WP_015587732.1\|126380_127547_-\|phage-tail-protein	gnl\|CDD\|370616	pfam09684, Tail_P2_I, Phage tail protein (Tail_P2_I). These sequences represent the family of phage P2 protein I and related tail proteins from a number of temperate phage of Gram-negative bacteria.	5.25232e-06
NC_021084.1\|WP_015587737.1\|130126_130639_-\|phage-tail-protein	gnl\|CDD\|284235	pfam06763, Minor_tail_Z, Prophage minor tail protein Z (GPZ). This family consists of several prophage minor tail protein Z like sequences from Escherichia coli, Salmonella typhimurium and Lambda-like bacteriophages.	3.75958e-09
NC_021084.1\|WP_081600831.1\|110737_110941_+\|hypothetical-protein	gnl\|CDD\|238828	cd01651, RT_G2_intron, RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable element with both gag-like and pol-like genes. This subfamily of proteins appears to have captured the RT sequences from transposable elements, which lack long terminal repeats (LTRs).	5.0045e-15
NC_021084.1\|WP_015587721.1\|106487_107183_+\|di-trans,poly-cis-decaprenylcistransferase	gnl\|CDD\|376506	pfam01255, Prenyltransf, Putative undecaprenyl diphosphate synthase. Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.	1.83394e-110
NC_021084.1\|WP_015587735.1\|129199_129664_-\|phage-baseplate-assembly-protein-V	gnl\|CDD\|368076	pfam04717, Phage_base_V, Type VI secretion system, phage-baseplate injector. Family of bacterial and phage baseplate assembly proteins responsible for forming the small spike at the end of the tail or bacterial pathogenic needle-shaft.	8.32608e-47
NC_021084.1\|WP_015587722.1\|107172_107799_+\|phosphatidate-cytidylyltransferase	gnl\|CDD\|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	1.39212e-36
NC_021084.1\|WP_015587733.1\|127810_128602_-\|baseplate-J/gp47-family-protein	gnl\|CDD\|164963	PHA02568, J, baseplate assembly protein; Provisional.	2.54538e-58
NC_021084.1\|WP_015587734.1\|128941_129196_-\|hypothetical-protein	gnl\|CDD\|269821	cd14671, PAAR_like, proline-alanine-alanine-arginine (PAAR) repeat superfamily. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat superfamily, where it forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). The T6SS is responsible for translocation of a wide variety of toxic effector molecules, allowing predatory cells to kill prokaryotic as well as eukaryotic prey cells. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. The PAAR-repeat proteins form a diverse superfamily with several subgroups extended both N- and C-terminally by domains with various predicted functions; the termini are exposed to solution, and do not distort the VgrG binding site. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes. It has been shown that PAAR proteins are essential for T6SS-mediated secretion and target cell killing by Vibrio cholerae (encodes two PAAR proteins) and Acinetobacter baylyi (encodes three PAAR proteins); inactivation of all these PAAR genes results in inactivation of Hcp secretion as well as T6SS-dependent killing of E. coli.	3.58704e-13
NC_021084.1\|WP_015587726.1\|111975_119118_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	2.72884e-21
NC_021084.1\|WP_051063868.1\|110551_110731_+\|hypothetical-protein	gnl\|CDD\|238828	cd01651, RT_G2_intron, RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable element with both gag-like and pol-like genes. This subfamily of proteins appears to have captured the RT sequences from transposable elements, which lack long terminal repeats (LTRs).	4.80862e-10
NC_021084.1\|WP_015587730.1\|125014_125479_-\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	1.41592e-23
NC_021084.1\|WP_015587723.1\|107813_108023_-\|zinc-finger-domain-containing-protein	gnl\|CDD\|370944	pfam10276, zf-CHCC, Zinc-finger domain. This is a short zinc-finger domain conserved from fungi to humans. It is Cx8Hx14Cx2C.	4.81874e-05
NC_021084.1\|WP_015587728.1\|123088_124582_-\|recombinase-family-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	4.32019e-40
NC_021084.1\|WP_015587729.1\|124575_125010_-\|DUF2924-domain-containing-protein	gnl\|CDD\|371394	pfam11149, DUF2924, Protein of unknown function (DUF2924). This bacterial family of proteins has no known function.	3.52664e-36
NC_021084.1\|WP_081600809.1\|111035_111584_+\|hypothetical-protein	gnl\|CDD\|369847	pfam08388, GIIM, Group II intron, maturase-specific domain. This region is found mainly in various bacterial and archaeal species, but a few members of this family are expressed by fungal and chlamydomonal species. It has been implicated in the binding of intron RNA during reverse transcription and splicing.	1.3277e-13
NC_021084.1\|WP_015587725.1\|108808_109747_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl\|CDD\|153216	cd01745, GATase1_2, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	0.00178743
NC_021084.1\|WP_015587724.1\|108094_108601_-\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	8.0375e-86

>NC_021084.1|WP_015587726.1|111975_119118_-|tetratricopeptide-repeat-protein
MPKVNIDPQSVKLQKEEKSLQLKNRIKRQYNPSDINIAKLFLAIREHRTGNPQLNKISEIEGLLTQVQNINDIDLNDIGNTPLHVAVSKKHPDIVEFLLNVPGIDPNIQNNQGDTSLHIAVSEDDEELVRLLLSKKAEMNIKNKDGKTPLDIARSNTQPNKEKIISTLEEHLNKSSNQVERLSEQEKEVHEKLRRFVEDFVFIYEGSLSEYYERLENQKGKPGKWADFINRVTRTGKSGTEQGERESKVIPLIGISVLQEAISGIGSYYNREELKKLIDQLYIFEKDPVKVREELVKSGIEIFQAFESQFVQVKADGSWQRAMAKLAKDAVSRVVDYYRQNNAKEFCAFSITEGIILGESKKYKQTSIGVPHIKSGHTLESKNLNSWNTAELFDKAGLVTIKSDGSADKYYRKRDGKSDTSKYGYRLLFKWELENKIKKFVREYSEEKPPREEYRYILKSDEEKWEGKLLDELNKQDPKLVEERLLSNFKEEMKQEAEKKVNELEDYIGKNFNELSSYIESNQNEIKRVLDELISQHQQASQEIADSIAEERKESRESFEKVDKKLDEIHSLIIAGQQVREPIWFDVKKPVSLFTGREEELIDLHNKVQRSSEKITILSQITSISGLGGIGKTELAREYIQEYSKDYYNDVIWINAESEVSIIESFTRLAKDKLKIDTKDANGKKKDIQAIVEEVYEFFSDSKSLFIFDDAEKSNYLNKFLPLHDLLTVGNEPYILITSRNQEWDRGIEVINLNELKSEEAIEFVKKSLSIEDESQNEKIKALVEKLQRFPLAIQQAIAYIEDQRITEEFDIDDYLEKYEKKTKDLLDSEVFMGIDNDYAKTTFSTWKITTNKIASDRENGKLALRVLNIISYLAPERISREVFLGLTGSSEEELRSAVRLLIKYSMVNGEQKQSVLSTHKLVQEVTRIVLEEEGKGKEVMDEVFKLLRASFPYGSDKLEDYVKKREFLPHLEAFLLHVDNWLKKNPKDKQKIEEDYLEGLLILISDGYFSLGNPKRQKDLLERALHILEKHYGVEHFEIGMILENLGIAYLILGDYQKAKDLTEKALPILESHYGEDHFEVAKTLLNLSISYGALGNYQKQKELLKRALPIFKKHYGEDHPEVAIVLENLATADRALGNDQRAKESLEMADKIYQKGEVAECLPNTSSGMRKREAKIGECELSWEDVDKFNTEEDAKRDFSKIKIDSEKFLHYIKDLPEDKRYQLIEIANKVEVTGGFRDLINKLSNNQKVMNHLNRVKKISSITMHGMMAKNVLADFLNGDYQGVAINVGFIAGGQGFARVAEVASREGLNLLSEGKALLGRSLRAASPFLARGTSAFIAYDLVNQVKAFKNGTEGALVGVVGDSIYLSVDAAEIGIEVAESFAILEGVSSVTGPIGSGIGAVVFVGTDVYMAVKKVDKIDQIIHLTGKEKFIEGLRAFIGMQPEQYIEELMEGKQLYNQLVKQGFEYLKEHSNIQSYVFPTSKSSVDSCRKVPYQQNICNMARFSILCLRKVNVTFYAEKCTTKFEIDLDSTVLLDRKRTDIRWSRARPDNPSGGKLFCFSQGNDEPAPSYGSYLCENAIGLSNNKIEGYTLIDLGEGKDYARGFKDSQNIFVVNDGSKEYYGGNKNDIFILQGDLIGGSLYGEGGIDTLDLTGFAHGVVTVDVYLNANIGITVYKHHGYHSFKINSVERVFGRKVEGDHIFSACETKFVDGNGGAEDQLDYVQIENNDCVYDIQVIIKPYTEIDNMALKGNFSYILPSQNGSASVKLLTNLESNHRFTFGYVLADVQSIDVEDQNSIRFNFFSKVINSNFSISISYNIMNNIIYQLKDSAEIKVGKERNLYAIQSTNKTIDEIIESYPAIANKLNMTIAVQSVNEYILVGHEKCEVLQNNPIHNSHLIKNGGENIYVITIASGKQRYDHSIFSIPEVNIYNLDKGSSIDTLDLRKVIKIIQQDDLRVHIGLPRIYQDGNDLLVKLEAEFGQSFPAEVLMVRLKDGLNWYEKLHIISNNIPMKISSELELKPLPLIFEKDKEIIVVTGQDVEEGTELIISRKGENYRFVRSNDNDLMITNAFDSTITRDDFCSITLSEFYKTPKMKTLSIKFADKGIVLRDHEKEINAARNVDSVKREYKDQVYNDVFSKYKQQNVAIRHRRHKEYSDLDKRFSENIRNSSTKASSWINDLFGWVKNSIGRFRAALPEILANYSNTAGTSQFSSEVCISNNVGLGFLLLQSFLDRKYPLPKFCSATHEEVLADTLDIMEEFKKTLKKTAKQSGVSVKGFDFFKVYSDIAGHVRNERYSKIPSTLYSAVKEAYPKNEKFLSTFKSSIGKMLDRQKMVNNHNQEQGIANVDPSFLLNRIVVESVNNGGLKGVNCAGQVA
>NC_021084.1|WP_081600809.1|111035_111584_+|hypothetical-protein
MRRAPQERVIKDLNPINRGWSQYYSSVVSCKIFSSLDNIMHRKFWKWAVFRHPNKGRCWIKRRYFKKYNNENWRFMTSNKVRLTIHSDHVIKRHIKVQKTRSPYDGDWVYWGNRLNRILDKSPKVIKLLKLQQSKCDQCQLWFKSDDILEIHHRDQNRKNNMIKNLSLLHGHCHDELHRRCA
>NC_021084.1|WP_081600831.1|110737_110941_+|hypothetical-protein
MSVIFYCDDFVIIHENEEIILKAKILVEEWLETIGLKLKPSKTRVSHTLRTIDETKPGFDFLGFSIR
>NC_021084.1|WP_051063868.1|110551_110731_+|hypothetical-protein
MEDGKLQSTKRGTIKGGTISPLLACVALHGLEQHVKKALTNELFQCMKRKYGKIPHKNA
>NC_021084.1|WP_015587725.1|108808_109747_+|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MHKCYNRVFNILLITFLLLSNIAYSEKVNKELSALTAENAVNYNIIVGLLQTDESQNIYEIFNNFGVKTIFIDYDKIINLKEIQEEFAKQDEILAKKLILDRIKAEVAKFIKEQKINRIFISDNFHSALNPYRQLVNEAIVKIVDDNPTIHLLAICGGLQDIMHAKEIEITNVVNDEKNHLKSASYPQKENMPLQQIKIVPGSRLEKVVARFLLPNQNGWFSTYFPNAHSGTVSNTTENRRRLELLGYKIAAFANDGVIEAIEDKHGNIYFQSHLEALVVKSDKNSRLSSQKVRQVSTLVAIAIINDFLHRV
>NC_021084.1|WP_015587724.1|108094_108601_-|pantetheine-phosphate-adenylyltransferase
MNINNKIGIYPGTFDPITFGHLDIIKRACKLVDKLIVGVAENVNKHTTFNIKLRTSMAENEVKGAEINADVISFNGLLVKFAKEQNASVIIRGLRAVSDFDYEFQMSWVNYKLSHEIETIFLPASEDTQFISSSFVKEIARLGEDVSSFVSQNVQTELINLNRVKNGE
>NC_021084.1|WP_015587723.1|107813_108023_-|zinc-finger-domain-containing-protein
MSEVRDNNLIVCCRGDENDDGSGHPVVYLHKEGEMYCPYCSKPMSEIVNSEEFQSVEVKAVNKKERTKG
>NC_021084.1|WP_015587722.1|107172_107799_+|phosphatidate-cytidylyltransferase
MVDNNFMVRTLSSIVILLIFSFATYFSDLSFYLLIFSIAVLSSFEWYNLTQGNRILYIFALLLIALPNASLIYLYNLPQGKYELIWLILTIWSIDITAYLFGKNFGGAKICPIISPGKTWSGLLGAVLAGVFCTIFGSIFLSLFPIFYSPIIGFTIAILAQLGDFTESLIKRVYNVKDSGGIIPGHGGVLDRMDSLIFTAPFIAIYIS
>NC_021084.1|WP_015587721.1|106487_107183_+|di-trans,poly-cis-decaprenylcistransferase
MLNLESLPKHLAIIMDGNGRWAKNQGMVKIDGYRKGSEVAFDIAKHCTTLAISYLTLYAFSMENWLRSENETDYLFNLFYSTLINEDKMKFIYNCNIKLNFIGNLSLLPSKIFDQIKKAEEVTHKNDGLLLTVAVSYGAKQEIIHAINNVIKGNIDCVLEEEFEKFLYTKDLPKLDLLIRTGGEKRLSNFLLWQAAYAELYFCDTLWPDFSCQDLSKALADYTKREKKYGR
>NC_021084.1|WP_015587720.1|104955_106182_+|hypothetical-protein
MDFDKADNAEDLDNKKLQLICKAYDIRLRSSQRVVDGINSMNYSKLEILCKYNNKFSYKGIEELLSDESIVNHINDYDDEMFSSMLNDAPSERNILEILKGEEVCNTNNEFESSGNEKNEEDYGYYDNFDYEEDEKNDPNNFAKEALGNKGINEKRVDDVQFYNDADVEIPPKNQNDIRNIRLIQWMIVESDGKLSEQNVTELLKDQSSIDRINSIGDKKLQLILKSNKFSGENIMELLGNQKVVEYLCFIDYEKFELIHNSDKFNSSNYTSSSYKIIRLLENQQVVEHINFIDYEKLKFILCNDKLLFSDIVRLLKNQEVVENIISFNIKKFRLIFYRDNLNYVDTIELLRNQEVVNRIGFTPFEELKSMCSHSSLSDIIKLLEDKNGPSNVLSGTRKEKMQVSYIS
>NC_021084.1|WP_015587728.1|123088_124582_-|recombinase-family-protein
MLKEVRCAIYTRKSNEDGLEQKFNSLDAQRVACEKYIKSREGWVALAKRYDDGGFSGKNLERPAIKELFEDVKGGEVDCVIVYTLDRLSRETKDSIEVTSFFRRHRVNFIAVTQIFDNNTPMGKFVQTVLSGAAQLEREMIVERVKNKIATSKEQGLWMGGTLPLGYDVKDKELIINEKEAKIVGHIFERYLELKSMAELARELNREGYRTKSDIFKKATVRRIITNPIYMGKIRHYEKEYEGKHEAIIEEEKWQKAQELIKNQPYRKVKYEEALLRGIIKCKSCDVNMTLMYAKKENKRYRYYVCNNHLRGKNCESVNRTIVAGEVKKEVMRETEKLYEKWEEKAEEWKNLSFGKQKEVVKKLIKGVMVKEDGIEVHSESEEKFIPIKKKGNKCTVVEPEGKTNNALLKAVVRAHLWKRQLEEGKYRSVKELSAKINIGTRRIQQILRLNYLAPKIKEDIINGRQPRNLKLVDLREIPMLWSEQLEKFYRFKQAVC
>NC_021084.1|WP_015587729.1|124575_125010_-|DUF2924-domain-containing-protein
MEKEIEKKVMNLEKKALVELRRIWKKVFGEEAPRYSKKYLIPRLAYRMQEKAYGEMSRKGTKRLEYLADRLEKGKRISSDKLPVEGTELILERGEETHAVMVTDKGLIYREEFFTSLSAVAGKIMGMSYNGPLLFGMRDKEKEC
>NC_021084.1|WP_015587730.1|125014_125479_-|ankyrin-repeat-domain-containing-protein
MLKFGKFNKSAEELLENSHENIYARDEKELHYAVDAKTVKLLVEKGANVNAADARGYTALHLAVTEKRLETVRELIKSGGNVNAEEYGSKCTPLHLACMIGEKEIVKELVKAGGEIEQADKFGMTAMDYAKNSKEITEILKKEIDRIEKLFMKG
>NC_021084.1|WP_015587731.1|125510_126212_-|ankyrin-repeat-domain-containing-protein
MSFSKSKFFKEVSSKDINKRNEEGETILHQAVEISDYKTVRFLIKKGAEVNARDKNGYTPLHCAVFAKSLENVKVLLRSGAEVNATQYVTGCTPLHSACKMGGAGVEIIKELVKAGAEVNQLNKYGATPMYYIWESEKYSLCDSKESEKASKFLREKGGVIKNRELTCYGIERLVGEIADMLNGSYLPELKIIEIEEIRKRDKSLIKEECQNLASKIISKVNEMIDEVVRRKA
>NC_021084.1|WP_015587732.1|126380_127547_-|phage-tail-protein
MKSLLRPNSTKQEQALVDATDYKVDPSCIRGFKFSLKEETLPWLIEEYELGEILRWVKDKRRAIVEGVKFQRLRGTPASLKIALKWANIEDITIIEEPPGKHFFELQVGIKEVPNDFFVDAVVELAKLSLPVRSRLMRIFNDYYNVQRFILDESLFGDLLSDYSGVKIEKDGPVLSFGRVNFFRSSGPVIRIIENYLRDHYERALSNDIYRLDVAILGETEPHTRDYKGIYERDHLWYNLKALYPLPQSLLPSIKFAKAQIVLSDSWKLGEINSCFPVGRIEEEGNKFVLGNDKLSGQHWSLKHKPILERFSIIHRYKVENYTDQKVRKYVLAEHNIYYKNDLYSEQKDSIHELEKHILVFYPGVLKWHEHRHLHRSWKNSQVICVIS
>NC_021084.1|WP_015587733.1|127810_128602_-|baseplate-J/gp47-family-protein
MEQPNIIEPLNFEEILSRMREELVKRDASFTALVESDPAIKILEVAAWRELLLRQRINEAVKGNLLKFATGEDLDSLAEFYGVERQNEEDDERFRKRIKAKIKGWSTGGNYRYHALSADSRVKDALVESTIPGKVQISILSTQLSTTGIVSEELLEIVKKQVTRDYIRVLTDTVTVIGCNITEIDIHSRMSISPIISEEEIKKQFIKKFEESRRLGWSVTRSWIIANLFVEGVENVELIEPKEDVVVLGNECAVLGHVKLDRI
>NC_021084.1|WP_015587734.1|128941_129196_-|hypothetical-protein
MGKAIVCVGDNCTGIPVHVCMSGSEDVFVNSRSVCRRGDILTIGETLTQGSNSVFVNGMGVTRTGDLVSCSFKVIGVSKNVFAE
>NC_021084.1|WP_015587735.1|129199_129664_-|phage-baseplate-assembly-protein-V
MLENNFAISELQRKMANIVRIGVVKEIDYEKAKVRVKIGEFLTDYLPWITSKAGKDRDWSPPDIGEQVMIFSPLGELSLGVVLGGIYQEKYPAPENKKEVSSLTFQDGTKLSYDKDKHHLEIEVVDKITLKAGESGIEMTKERIKLKGRRIDLN
>NC_021084.1|WP_041581447.1|129650_130127_-|hypothetical-protein
MNWKDLHNAICTTLKKEISAIQTCEIYPSIRKELLAPAVFIELSSLEQGKDPGTEELALRAKFEARIVIDSTIENASLIVRTLAAEVAKVVNKNTWNVKNVSPGEFISGGGDDFRPELDAYLVWMVEWVHTIHVGRSIWKEGKFMPHKIEIGEINVRK
>NC_021084.1|WP_015587737.1|130126_130639_-|phage-tail-protein
MFNIKTSNNINEIISNIDGKEQKVKLAAIKALNRTALWLKLKTAKEISEEKKIKLSLIRKRLRIFKAKTSRLEVLIRANLYDIRASTIGKIQKTRRGSKVGKHEFIGGFAAVMPKGNSGMFKREGRAALPIKEVKLPLEPEASRIIENLVNYEVEKVFTKFFKRELSCRV

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Crispr_ID: NC_021084_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021084_3

409476-409729

Orphan

Consensus_repeat	Method
AATTATCCACTACATTAACATTTGCTCCGTTTTTAAGCAATAATTTCACCTCCTCT	PILER-CR

2 spacers

The CRISPR arrays of NC_021084_3

>merge|NC_021084|3|409476-409729|PILER-CR
AATTATCTACTATATTAACATTTGCTCCGTTTTTAAGCAATAATTTTACCACATTCTTATGGCCTCCCTGAACAGCTAAATATAGAGGAGTAGCACCGAAACGATTTCTTACATCAATATCTGCTCCGTTTTTAAGCAATAATTCCACCTCCTCTTTACAATTTCCGCAAGCAGCATAATGTAAAGGAGTAAAACCATAATTGTCCACTGCATTAACATTTGCTCCGTTTTTAAGCAATAATTTCATTTCCTCT

>NC_021084|3|1|409476-409729|PILER-CR
AATTATCTACTATATTAACATTTGCTCCGTTTTTAAGCAATAATTTTACCACATTC	TTATGGCCTCCCTGAACAGCTAAATATAGAGGAGTAGCACCGAAACGATTTCTTACATC
AATATCTGCTCCGTTTTTAAGCAATAATTCCACCTCCTCTTTACAATTTCCGCAAG	CAGCATAATGTAAAGGAGTAAAACCATAATTGTCCACTGCATT
AACATTTGCTCCGTTTTTAAGCAATAATTTCATTTCCTCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021084.1\|WP_015587949.1\|419891_420446_+\|50S-ribosomal-protein-L9	unknown	unknown	gnl\|CDD\|234659
NC_021084.1\|WP_015587944.1\|413226_414201_+\|LD-carboxypeptidase	unknown	unknown	gnl\|CDD\|132882
NC_021084.1\|WP_015587930.1\|391607_393962_+\|type-IV-secretion-system-protein-VirB4	unknown	unknown	gnl\|CDD\|273346
NC_021084.1\|WP_015587929.1\|391190_391565_+\|hypothetical-protein	unknown	unknown	unknown
NC_021084.1\|WP_158673923.1\|422159_422249_-\|hypothetical-protein	unknown	unknown	unknown
NC_021084.1\|WP_015587938.1\|404877_406374_+\|murein-biosynthesis-integral-membrane-protein-MurJ	unknown	unknown	gnl\|CDD\|240528
NC_021084.1\|WP_015587942.1\|409989_410991_-\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NC_021084.1\|WP_015587943.1\|412609_413227_+\|lipoyl(octanoyl)-transferase-LipB	unknown	unknown	gnl\|CDD\|237680
NC_021084.1\|WP_015587948.1\|419609_419888_+\|30S-ribosomal-protein-S18	unknown	unknown	gnl\|CDD\|178997
NC_021084.1\|WP_015587936.1\|401934_403872_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NC_021084.1\|WP_015587933.1\|398943_399588_-\|dienelactone-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|334855
NC_021084.1\|WP_015587947.1\|418836_419610_+\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|172564
NC_021084.1\|WP_015587950.1\|420574_421876_+\|adenylosuccinate-lyase	unknown	unknown	gnl\|CDD\|181000
NC_021084.1\|WP_015587932.1\|398158_398938_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187576
NC_021084.1\|WP_015587931.1\|393942_396759_+\|hypothetical-protein	unknown	unknown	unknown
NC_021084.1\|WP_015587946.1\|415467_418788_+\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|235554
NC_021084.1\|WP_015587934.1\|399685_400051_-\|hypothetical-protein	unknown	unknown	unknown
NC_021084.1\|WP_015587935.1\|400138_401926_-\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|238518
NC_021084.1\|WP_041581317.1\|414419_415268_-\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NC_021084.1\|WP_015587940.1\|406757_409253_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379224

Protein	Function_ID	Function_description	E-value
NC_021084.1\|WP_015587949.1\|419891_420446_+\|50S-ribosomal-protein-L9	gnl\|CDD\|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	8.18551e-53
NC_021084.1\|WP_015587944.1\|413226_414201_+\|LD-carboxypeptidase	gnl\|CDD\|132882	cd07025, Peptidase_S66, LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein. LD-carboxypeptidase (Muramoyltetrapeptide carboxypeptidase; EC 3.4.17.13; Merops family S66; initially described as Carboxypeptidase II) family also includes the microcin c7 self-immunity protein (MccF) as well as uncharacterized proteins including hypothetical proteins. LD-carboxypeptidase hydrolyzes the amide bond that links the dibasic amino acids to C-terminal D-amino acids. The physiological substrates of LD-carboxypeptidase are tetrapeptide fragments (such as UDP-MurNAc-tetrapeptides) that are produced when bacterial cell walls are degraded; they contain an L-configured residue (L-lysine or meso-diaminopimelic acid residue) as the penultimate residue and D-alanine as the ultimate residue. A possible role of LD-carboxypeptidase is in peptidoglycan recycling whereby the resulting tripeptide (precursor for murein synthesis) can be reconverted into peptidoglycan by attachment of preformed D-Ala-D-Ala dipeptides. Some enzymes possessing LD-carboxypeptidase activity also act as LD-transpeptidase by replacing the terminal D-Ala with another D-amino acid. MccF contributes to self-immunity towards microcin C7 (MccC7), a ribosomally encoded peptide antibiotic that contains a phosphoramidate linkage to adenosine monophosphate at its C-terminus. Its possible biological role is to defend producer cells against exogenous microcin from re-entering after having been exported. It is suggested that MccF is involved in microcin degradation or sequestration in the periplasm.	2.06906e-86
NC_021084.1\|WP_015587930.1\|391607_393962_+\|type-IV-secretion-system-protein-VirB4	gnl\|CDD\|273346	TIGR00929, CAG_pathogenicity_island_protein_23, type IV secretion/conjugal transfer ATPase, VirB4 family. Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).	4.58401e-121
NC_021084.1\|WP_015587938.1\|404877_406374_+\|murein-biosynthesis-integral-membrane-protein-MurJ	gnl\|CDD\|240528	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	2.10034e-121
NC_021084.1\|WP_015587942.1\|409989_410991_-\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	1.32595e-35
NC_021084.1\|WP_015587943.1\|412609_413227_+\|lipoyl(octanoyl)-transferase-LipB	gnl\|CDD\|237680	PRK14341, PRK14341, lipoyl(octanoyl) transferase LipB.	3.21905e-136
NC_021084.1\|WP_015587948.1\|419609_419888_+\|30S-ribosomal-protein-S18	gnl\|CDD\|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	8.99992e-31
NC_021084.1\|WP_015587936.1\|401934_403872_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NC_021084.1\|WP_015587933.1\|398943_399588_-\|dienelactone-hydrolase-family-protein	gnl\|CDD\|334855	pfam02230, Abhydrolase_2, Phospholipase/Carboxylesterase. This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.	2.37116e-30
NC_021084.1\|WP_015587947.1\|418836_419610_+\|30S-ribosomal-protein-S6	gnl\|CDD\|172564	PRK14074, rpsF, 30S ribosomal protein S6; Provisional.	2.53266e-156
NC_021084.1\|WP_015587950.1\|420574_421876_+\|adenylosuccinate-lyase	gnl\|CDD\|181000	PRK07492, PRK07492, adenylosuccinate lyase; Provisional.	0
NC_021084.1\|WP_015587932.1\|398158_398938_-\|SDR-family-oxidoreductase	gnl\|CDD\|187576	cd05266, SDR_a4, atypical (a) SDRs, subgroup 4. Atypical SDRs in this subgroup are poorly defined, one member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is related to, but is different from, the archetypical SDRs, GXGXXG. This subgroup also lacks most of the characteristic active site residues of the SDRs; however, the upstream Ser is present at the usual place, and some potential catalytic residues are present in place of the usual YXXXK active site motif. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.41311e-66
NC_021084.1\|WP_015587946.1\|415467_418788_+\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NC_021084.1\|WP_015587935.1\|400138_401926_-\|aminopeptidase-P-family-protein	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	2.39037e-124
NC_021084.1\|WP_041581317.1\|414419_415268_-\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	3.4599e-28
NC_021084.1\|WP_015587940.1\|406757_409253_+\|hypothetical-protein	gnl\|CDD\|379224	pfam13502, AsmA_2, AsmA-like C-terminal region. This family is similar to the C-terminal of the AsmA protein of E. coli.	2.43474e-06

>NC_021084.1|WP_015587940.1|406757_409253_+|hypothetical-protein
MKLSLYAISSILFLLILMHVAATFKDWSGYREYIVKELEKTYDAKVHVGGKIEVSLITPKLTIHNVYVQYNKNKEQKLSDLISAKKIEIRPSLLSLFSFSLQPKSISFLGMKSNKENLLNIMNTKANDNTVDILIKDSQISFGADTINIKEVAIKKNKQFFGEVQIGDNNYDFSGKVNVTKNNVHISVDSNFANLLFKGNRNQEELKGNLVLTINNNSDSMSDLAKIINLSFLSYVIPSENIEISSNINLNESEFTATDLKIESKSMQGTGIIQNDRKSDHTNINISFSKVDLKNGSHKTTDMKGLLESFREVVPKNLSLDFNMEASNIQYQNRILDKFHATLKFANGEIKVDTLLQFPGTNNISRLSGKVSNNGNLSEFNGDILIKGESFISHILPSIKMQEREKSQFTASSKLYLAPRILSLSDIRLLNNKESWQGSIKVNHTKKHNMIDSKFSIYNINIDKYDYSLFSKVQWLKNLKYDVNIRTSVKDSIFNGTKIEDLDFSLKIQENKLVADKIKLFGEDFDITGSVKILVDQKYTKPLLDVNLTGNKFNGNIFKLPKLLEVKRNSKNEINQIQWSTKQLNFLDEKGDFDANVQIKTTEFKIGQNVLKDFNLDTVIRNNTITIKQISYILEHGQMFFQGYLKAGSIHTKFSIANLDTKEVIGVNNINGKISLSGEIKTQGTSFNDWASNLSGNVNFQAQKIEFTNVDFNSFITKLLSSKNKPEISKLAYVDIYNGSTLFENINGKVSIKNGICSTSSQFSIDQASGSISSNLILSNFSLNSIFRLFFILPNHNSPLYIEAHLDGPIWSPKMSFDVDQIFTTFNWQEK
>NC_021084.1|WP_015587938.1|404877_406374_+|murein-biosynthesis-integral-membrane-protein-MurJ
MFKSIFTFSFFTAISRISGLIRDVLIATVIGATSLADIFFSSFRFANLFRSFFAEGAFTTSFIPLYSAESYDNKKAFNFASSVISITFIILVIFCLITQTFFPYMIKIFTPGFDQNKFTFTVTLSKIMMPYIIFVSIASLIGGMLQVKQHFASTAISPIILNLCLIISLFLPYIETPAHNLSIAVLIGGILQLLLIIFSAYKLKAFFSFSLELSNEVKLFFKRVIPAIINNCVTQISLWIDTIMASFIPNAVSYIYYADRLNQLPQGVIGTAIGTVLLPLISKRINDTENIVKIQNKALNIGLILIMPITAAFIIIPDIILLTLFSYGRFDYYAVQQTIPTLVAFSLSLPAFIINKVLLPTFFARGKLKIPTMFSLTCLGINVILNLLLMNKYQHIGIAIATSISTWINSILLINYLTVNKMYKISQALLLNIVKILTATLVMSIVLYLSNYLSAGLFFDRGLARIVYLVTLIALSVIIYSSTLYLIFRGNLNNLKYV
>NC_021084.1|WP_015587936.1|401934_403872_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MNKYDVVVVGGGHAGCEAATAAARLGANTLLITHKISTIGEMSCNPAIGGVAKGVVVREVDALDGIMGRAIDRASIHSVVLNGSRGAAVWGPRAQADRKLYKKAIQEIILNYNNLTVKEESVDDFLIESDSNGESYIKAVITDSGERILTIRVVLTTGTFLRGVIHIGEQTTPSGRMGDKPAIELANTLKKYDFKLGRLRTGTPPRLDRVTINWSVLQEQMGDNPPTPFSYLTEKINQPQVSCFITHTNEHTHRVIRENLHRSASSYLDNVIAPRYCPSIETKVKKFAEKNNHQIFLEPEGIDDNTIYPNGISNSLPIEVQYEMIKSIKGLENAEILRPGYAVEYDYIDPRELFHTLETKKVKGLYFAGQINGTTGYEEAAGQGIIAGINAALSLSQKSFVLHRTDSYIGVMIDDLVTKGIAEPYRLFTSRAEYRLAIRSDNADRRLTQKGYDIFLVSHERYSVLQNKLKSIKQLEEKLESLTITPEQLRFYGVKISYDGIRKTALDLLGYPNIDWNKLREIWPELNNVMCWNDKTECWNDITMVSTAKNEICEAVAIEAKYKPYLVRQEADMRFLQEEVSTQIPTNFNYSQIKGLSSEVIEKLQAIKPATIGIAKQIQGITPAAIVSILVYLRNKKTKIAANSA
>NC_021084.1|WP_015587935.1|400138_401926_-|aminopeptidase-P-family-protein
MSKIEEFRSFMHEINVDAFMLHTKDEYLNEYSKELTELCGFTGTNGLLIVTKTNSCPFFTDGRYITQARSQLDQNNFQVYNIQEEDPHRWVKANLTLTTSLGYYSRYFTVKEIRKYESICKLVPYLIEKEGSHKTQTIVSHTSGESSKSKCERVAKSIEAEAVLLTDPNSISWLLNLRNESAEYTPCIWGRAILYKSGNVDLFVQDKQHSTIQADLDNNVSIFDICELESSLCKLSSMMIDPSTTPMSIMNAIDPLYNHYLNEKSASVSFQCLTRNKKAWIPVSSTGMTIGNEKGLIENKQIIEKEDPCLIHKAIKNQIEITGAISAHIKDGVAVTNFLYRLIGNEITELEAEAKILEYRRKQDLFKQPSFPTISAFNKNGAIIHYRASSKTNKAIKKDGLYLIDSGGQYLDGTTDVTRTIAIGNPTNEQRAHYTIVLKAHIAIASSVFPPGTTGGELDILARIHLWKFGMDYMHGTGHGVGSYLSVHEGPQAISKGNKVELMPGMILSNEPGYYIPGKYGIRIENLMYVEKQENGFLNFKQLTSIPYDKKLIDVQMLTEDEIKWINSYHQFVYKNIENGIKDKEWLKRVCEALK
>NC_021084.1|WP_015587934.1|399685_400051_-|hypothetical-protein
MTDKVQDDEFMKQYMDTCKEQIEKLTSDPNLLQQTLKPFMQMSQQLMAGGMLEGNMPSMIPDMGGMDINKMIAQMKEMYDYIKSNHKELMRKDASQIQELDDSSRRLRGLVKKLIEKVEAK
>NC_021084.1|WP_015587933.1|398943_399588_-|dienelactone-hydrolase-family-protein
MIELKSQEICPNGNKKNLIIFFHGWGSSGDNFVHLAKVMGKFLPDSYLVIPNAPFKREIGDGYQWFSLEDRSEEALYNGVKNAASIVNHFIDAKLKELNLKDMQLSLVGFSQGAMLAMHVALTRLQSCASVVAYSGRFLSPSKTAPEIKSKPSICVIHGDADDMVPFSSLDLAVKALKENGVNAQGYPIHGLGHIINEEGIKLGVEFIKKNFKN
>NC_021084.1|WP_015587932.1|398158_398938_-|SDR-family-oxidoreductase
MHLFCFGYGYVAKFLSQKLLNLGWKVSGTSRNKDIQLFNYEKVDQDLLKSVTHVLVSIPPDGDDVMERYGHCLENIKWLGYLSATNVYGEHCGNWVNEESETKPIEIRGKKRLKSEEKWLNSKLPVHIFRLAGIYGPGRNALIDLQLGKARNVKKKFSRIHVEDISNVLFSSMQNIKPYEIYNCADDLPATQSEVVTYAAELLNISPPEPVEISSVPNYARGFYLGSKKVSNTKIKKDLGVSLVYPDYKVGLKSLYILE
>NC_021084.1|WP_015587931.1|393942_396759_+|hypothetical-protein
MKNVKLNFLLIFSLIFCLSYQGYADCPRFVESNTDIEANASKVGKGFWNFFTGKWGSLNFDPHLLKEIKVTMVKDQGVGGYFDPKIKVCDYEGNDNCYILSSGTFCRKIYGTQSTGAGISAAAFIDWEGDKTKAGGEIAQGLGWEWVDGVTDEEKVKFANSPKICACSQKGACMSGISSWGSRVFSGENIFRLGEMEKACDTCYQTKVKCAPVQLAPGPPPFCEQLAMSPPQVRIVPITNEDNDYFHPRVGVIIGELKERRELPFPRVISSNKNIQSATYSIPDKDTHHHFNTYRKKGQLCTEYYGTEREESKRKLQFPARCFPAPPAPKIEEVSIPKPNEGKGENTLKVKMKISENVCTYDARGTHSNGICTFYVNKNSPTYIGHLPLIVVKPAIVEKTTNKGNRKSDIDNIIEGVLKNNSQFEVLKKYGYVPDVETECKELQNGKCKLDGSGYSKVEIKYKENPKSKMLCLSGWQPEPEELVLKKGSELISLKSVGASYDKHNTVYSKESNQSYYFPCNETIEVLAKPQDALDEIIFNKKGYISIPAENKPRDNCMAKEDKEVDTKQNCDKCKTVYELTDGKYEEKNCNHGDDGCLCFDGVCSRSTQYIGKDNKPFYLRVLQDESGVVTKLDNPIKANRTEVFFADKLCRFDLDGLKKRLREIIIAQLKHKKQIIENRDQKLYELGDGYTDDLSMYDYVEIEAWGGGEAGHIADKAQSTENRPGTPGDYIKAKLRVNPSYPYIKVKVTEGGSGQENHISNKDGGPTLIKMCRDLSETICKDLITVAGGGTHRIYGGRYYKDTIIHEESLKLKEEIKKGEKLNSSKDNKIAYIENGEIGYKDVTKCSKNYVNKTYGAGGCINESSKSYSKGAPGYVKIKPIFDEINKERVKKIDDAIEKMIQNPDDITGIDDSLINKLDQKIIDTIKEEIRKELLGL
>NC_021084.1|WP_015587930.1|391607_393962_+|type-IV-secretion-system-protein-VirB4
MQPKIPATSSNSEKKNNLALLESINLDFIPYACHYDEETILTKQGELLKIIKLEDYSSVDNYGDLRTEIRKSISKNIKSLYFTVWIHTVRKRNKLILQWNKTADFSDQLHSTWFNKLVDSKLQYINELYIVVLLSDFGKHINNAFFFGRIKNRHKLFLQKNHQELQKITDLIQKDLEPFGAKKLGLRSSEGKIYSQMMEFLHYIITLTHKDYPICERDLSQHVKNLKVAFGFNKFQTSFEGQQKFGSIFCIKEYREIPLENIDRCLQLDSELIITEIIIFTSNNKAVKEFKKQINILQISEDNTLLQNSGINEIIELEKISAMDFCQQKIIVTIFADDKNRLAKNISDLSSVMSLIGLMMFRTDLHMENHFWAQLPGNFAFVTQPKNILEKYACSFAMLHDFTSGTLKGGRWKEAVTVFFSKKGSPYFFNFHGKKNNGHTTILGAPNSGRTSLINFLLSESRKFNPRIVILDNTGKSIIFTKAVSGQYYIIGPKYKDKSLKFNPLNIEDSASNRNMLVELIKRMVADASLVDVEEKTKKIVDSIFTIPRESRSISQISEVLLLLGGKISKWCGEGEFAYLFQDGDESDIDWGTKTISLNTANLTKQKECMSVILYYFLYSFEAKCDGSPAILVLDEAWEISNIFPTEGEFDDWMQRMTKLNVVVILSTENLNLAFASKFTQYLDKHVDTRILMPNINANRLYMKAFSLSKEELNVILQTPTQEGLFLIKQYKGLVTLNLDLKNIKEIHVLSANKETIKYMYEAMKEKGEKVSKWLPVFYEKCKA
>NC_021084.1|WP_015587929.1|391190_391565_+|hypothetical-protein
MHIQLGRVFAIVALLSFIFMSCSSKASDELKNIPGTLKELISSFSVKDTVENISPSTIIGLCIATVILAVVFRGLIFFMIIFGVLIMMFGSTEKATDYLKEKFNFAKDIQLQSNNKKEDKDSVR
>NC_021084.1|WP_015587942.1|409989_410991_-|ankyrin-repeat-domain-containing-protein
MNEREQRELDELLMNSSKGENIQQITELIEAGANINAVKIEQKETPLHIAIRYGHKEVAEFLLNEGANINALERRKWTPLHTAVKSGKMEVAELLLDRGANVNAVDNLDMTPLHFALKYNREELVRLLLDRGANVNSVDKKGRTPLSIVASDDYQIGYCDKPMVVRTIIAYAVVHSGITTKPECIVKNIELSKFWDDYQNEMMNIKLNNSNISLYQFLRENDENKLAGYLSDREYDEIRCSDKLECISEFPEHADKIVSQFDKSLARRDLLDKSRAAIENSNLQVLCQVFNEITYHLTDKELKNIIEAFPSQNLDNPSAEQLQGASQVRHRFS
>NC_021084.1|WP_015587943.1|412609_413227_+|lipoyl(octanoyl)-transferase-LipB
MTEWLISNQFTDYNHSVKFMEAKIQQIYNNLSDELVWLLQHPPLYTAGIGATDDDIIEKLFPIYKTGRGGKYTYHGPGQRIIYLMLNLKKRNKCDIKLYIRDLSNWIINVLKHFNILGEFKEDRIGIWVNNNGVEEKIAAFGIRLRKWVTYHGIALNVSPNLSHYEGIIPCGLKDYGVTSMEKLGVKVSLCELDDILKQEFHKIF
>NC_021084.1|WP_015587944.1|413226_414201_+|LD-carboxypeptidase
MYSFILYFLCLLLTNPAHTINQVDIIAPSSKGKESDLPTIREYVKTLGFNPHISEKIYSNDNPFYSNSDEFRANDLVNALTDDSKIIWCIRGGEGASRLIPYLEKLPNDKKERIAQNKNKKILIGYSDITALHIYLQVQYDWQTLHGTMLEMIVNNSVAESSVEKLKELILNQRNSIRFDNLKMINNGVRLKNGRLESKIIGGNMTLVENSIGTAWQINAKNKILFLEDIKVYPYSIERSLDHLKQAHIFDGVDAVIFGDFINCYNDNLVEVVKERFAKSVNFPVFTIKGVGHGHTNDPLPFNTHTTISVQDEKEFMDVQQLYK
>NC_021084.1|WP_041581317.1|414419_415268_-|ankyrin-repeat-domain-containing-protein
MALEYESLEEVLSTIEVKEGLNKDNIIKELKTKLEKQDQGLYKEWEKDEFGVNHGFSLNISGIEYSKLPLLIIAARNGYTKTVNALIQAGANVNAVDQCKRTPLHHAALNGRVDTVEVLIKERANVNAVDKDKRTPLDHAALNGYVDIENALITAGANVNAVDKNGITYLEYAKMHIELYAKSESVVKALLDAGGRSFVKARNKAMIAGGVNTLLGTSIAVALFTTGTITAQLIPIVIAVVAVTAAALVVGYATYELLKPSTKVDGAEKSSAALINGQQGVC
>NC_021084.1|WP_015587946.1|415467_418788_+|DNA-polymerase-III-subunit-alpha
MFIHLRVHSVYSLLESSVKIEELIGLCLQNKMPAVAVTDSGNLFGSLEFAEYSANRGIQLIIGCNIIVRHLEQNLSILLLAKNEQGYTNLVTLVSESFKKRKNNSDIPYVDFDELLNLSSGLIALTDGYDGILAQLLLKQDKETIKKLLSAFDGHLYVELQRHGLNKELELEEALIDFAYQRNIPLVATNDVFFPNKSDYEAYDILTCISEGSYALENNRKKLTTEHYFKSVAEMEELFSDIPEAIYNTLVIAKRCSYMPRSRQPILPKFPCRENKTENEELREQAVSGLKLRIANETDIDLKQYYDRLNYELSVITSMNYAGYFLIVSDFIRWSKANGIPVGPGRGSGAGSIVAWSLQITDLDPIKFGLIFERFLNPDRISMPDFDIDFCQEKRDLVIDYVWKKYGYVAQIITFGKLQARAVLRDVGRVLQMPYAQVDKISKMVPFNPVNPVTLSQAIEFDQNLQKERDSDEVIAKLLDISLKLEGIYRHVSTHAAGVVICDQKLENFVPVYYDPNSALPITQYSMKYVEKAGLIKFDFLGLGTLTLIDHVCRLINRDEKKFDISSVSLADQRTYEMLSRGDSIGVFQLESSGMREALIKLKPDCIEDIIALISLYRPGPMDNIPTYVARKHGLEKPDYIHPLLEEVLKETFGVIIYQEQVMEIARILSGYSLAEADLLRRAMGKKIKEEMDKQRELFVQGATKHGVDYDRASYIFDLVAKFAGYGFNKSHAAAYAIISYQTAYLKANYPLEFFTALMNLNIDDRDKLNLFYHAAKFSGVAVLSPDISKSKAEFSIEGEHIRYGIAALRNVGFAIAEGIVNAPYKDIWEFIQNLGHIINKRALESLIKSGTFDSVHKNRKQLYESIDTLIYFANKNRQSNQAALFGNLDILKPKLENVEDFNEEEKLEHELFSLGFYLTNHPLEKFRTLLKKLNIGFIGESKTIKTAGVILNVRMRTSERGRFVILTLSDPHNVSEIAFYNNEIIEEKRNLFSPGAFVIIDLEISENTTRLSGKDISEFTEKVTSLMKGLVLTAVCADSQKVAEELNAVLKNGGKTKIMLKFLLEKHKVSILLPGTYSITPQAIYEISHLSWIEDVEINTNNLLI
>NC_021084.1|WP_015587947.1|418836_419610_+|30S-ribosomal-protein-S6
MNLYEFTFIAQPNLLQQEVEEMVQELAILLKNIKADVISQEVKGLIEREHSTVTKQELEASTESIKKSLIVYSDFLETLTKILWVELEEDFSNLKEIKSRIDKELKNELSDTGIKQNFMDLPGANTKSAFIYNVVNAFKENISQYLIKLLQEVLKSFKIVDSNQLNKTLEVLLKNIEASGLIKYEYWGLLDFAYPINKMKSGHYCMMCISFTSSIMDEFERRVKLNENIIRHLSVRVNEFFKGKSYMMDKQIEEKSA
>NC_021084.1|WP_015587948.1|419609_419888_+|30S-ribosomal-protein-S18
MMKRRNSFNNSYVSVNNRTGFRRPKVCPLAASKDEDIDYKNIDLLSKFTSDYGRILPRRLTGVCARKQRKLRLAIIRARFLALAPYCTKKVR
>NC_021084.1|WP_015587949.1|419891_420446_+|50S-ribosomal-protein-L9
MLIILKENITTLGKLGEVVKVKPGYARNFLFPQKKAMKATKENLIKLEEQRLLLEEENTKKLNAAKVLASSLHDKFIILIKQASEDGKIFGSLTTREIAKTLLQEGYDISHHSLSLGGISIKNLGEYQVNIELHSKVIVPITIYVVRSEKDAHELRQAKLQNQKSEQQEAEQDASKEATDGDDS
>NC_021084.1|WP_015587950.1|420574_421876_+|adenylosuccinate-lyase
MIPRYSRKEISSIWEEKNKFNIWLKIEKLACEAQAKLKVIPSDVAEKLSGAIEFDIERINEIESIVKHDVIAFLTYIAEKAGVDVRYLHYGMTSSDVLDTCLAVQLKESCDILLENLKNILAALKKKAEDYKNIVCVGRSHGMHAESTTLGLKFARFYAEFKRNYQRLISAKTEISICKISGAVGNFSNVDPFVEEYVAKEMGLIPETISSQVIPRDRHAIFFSVLGVIASSIENIAVEIRHLQRTEVGEISEYFSTGQKGSSAMPHKCNPILSENLTGLSRLIRSYVFPALENVALWHERDISHSSVERCIAPDACIAMDFALVRLTDLIDKLVINKENIEKNLNSSKGLVFSQRVLLELVNSGLAREEAYKIVQSNAMKVKQNNSDFLAELKQDKFLLEVINSKKLESLFDLKYYTKHIDHIYSKVFNEAE
>NC_021084.1|WP_158673923.1|422159_422249_-|hypothetical-protein
MPRHWDPENFTLNECMRLSLYRCQCQLLG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

73321 : 162458

Wolbachia_phage(64.86%)

transposase,capsid,head,tail,terminase,plate,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015587703.1\|73321_74341_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_007302820.1\|76706_76943_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_015587704.1\|76939_77530_+	septum formation protein Maf	NA	NA	NA	NA
WP_015587705.1\|77521_79741_-	hypothetical protein	NA	NA	NA	NA
WP_015587706.1\|80121_81459_-	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_015587707.1\|81718_82222_-	hypothetical protein	NA	NA	NA	NA
WP_015587708.1\|82509_84168_-	chaperonin GroEL	A0A240F779	uncultured_virus	7.3e-131	49.7
WP_006012576.1\|84257_84548_-	co-chaperone GroES	A0A221S331	uncultured_virus	1.1e-10	35.1
WP_015587709.1\|84661_85459_+	folate-binding protein YgfZ	NA	NA	NA	NA
WP_015587710.1\|86376_87213_-	magnesium transporter	NA	NA	NA	NA
WP_041581303.1\|87288_88239_-	hypothetical protein	A0A0F7L1J2	uncultured_marine_virus	9.3e-06	26.8
WP_006013958.1\|88741_89731_-	ribonucleotide-diphosphate reductase subunit beta	A0A1B1IW95	uncultured_Mediterranean_phage	2.7e-104	56.1
WP_015587711.1\|89860_90199_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_041581304.1\|90251_90779_-	hypothetical protein	NA	NA	NA	NA
WP_015587713.1\|90975_91704_+	DNA repair protein RecO	NA	NA	NA	NA
WP_015587714.1\|91726_93103_-	PleD family two-component system response regulator	G3MA91	Bacillus_virus	2.1e-22	35.8
WP_015587715.1\|93074_93365_-	hypothetical protein	NA	NA	NA	NA
WP_015587716.1\|93370_98041_-	NAD-glutamate dehydrogenase	NA	NA	NA	NA
WP_015587717.1\|98068_100630_-	ATP-dependent chaperone ClpB	A0A223W0B1	Agrobacterium_phage	5.6e-122	35.0
WP_015587718.1\|100848_101256_+	hypothetical protein	NA	NA	NA	NA
WP_041581305.1\|101461_101659_+	hypothetical protein	NA	NA	NA	NA
WP_081600808.1\|103095_103464_+\|transposase	transposase	Q9MCT5	Escherichia_phage	6.2e-06	29.9
WP_015587719.1\|103639_104812_-	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
WP_015587720.1\|104955_106182_+	hypothetical protein	NA	NA	NA	NA
WP_015587721.1\|106487_107183_+	di-trans,poly-cis-decaprenylcistransferase	R9W0U9	Flavobacterium_phage	5.2e-22	46.3
WP_015587722.1\|107172_107799_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_015587723.1\|107813_108023_-	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_015587724.1\|108094_108601_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	6.4e-30	45.9
WP_015587725.1\|108808_109747_+	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_051063868.1\|110551_110731_+	hypothetical protein	NA	NA	NA	NA
WP_081600831.1\|110737_110941_+	hypothetical protein	NA	NA	NA	NA
WP_081600809.1\|111035_111584_+	hypothetical protein	A0A0U4J920	Pseudomonas_phage	1.7e-20	35.4
WP_015587726.1\|111975_119118_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015587727.1\|119760_121563_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015587728.1\|123088_124582_-	recombinase family protein	Q9JML1	Wolbachia_phage	3.3e-255	89.5
WP_015587729.1\|124575_125010_-	DUF2924 domain-containing protein	Q9JML2	Wolbachia_phage	9.0e-65	90.0
WP_015587730.1\|125014_125479_-	ankyrin repeat domain-containing protein	Q9JML3	Wolbachia_phage	9.7e-49	86.0
WP_015587731.1\|125510_126212_-	ankyrin repeat domain-containing protein	A0A1B2LRT4	Wolbachia_phage	9.1e-75	81.4
WP_015587732.1\|126380_127547_-\|tail	phage tail protein	Q9JML5	Wolbachia_phage	8.5e-219	96.3
WP_015587733.1\|127810_128602_-\|plate	baseplate J/gp47 family protein	A0A1B2LRR9	Wolbachia_phage	2.9e-117	86.4
WP_015587734.1\|128941_129196_-	hypothetical protein	A0A1B2LRW2	Wolbachia_phage	5.0e-15	75.6
WP_015587735.1\|129199_129664_-\|plate	phage baseplate assembly protein V	Q9JML8	Wolbachia_phage	2.0e-70	85.7
WP_041581447.1\|129650_130127_-	hypothetical protein	Q75QM3	Wolbachia_phage	3.3e-68	83.2
WP_015587737.1\|130126_130639_-\|tail	phage tail protein	A0A1B2LRS9	Wolbachia_phage	5.6e-74	87.4
WP_015587738.1\|130631_130943_-	hypothetical protein	E9P615	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.5e-45	89.3
WP_015587739.1\|130942_131947_-\|capsid	major capsid protein	Q9JMM2	Wolbachia_phage	5.9e-192	97.6
WP_015587740.1\|131963_132338_-\|head	head decoration protein	Q9JMM3	Wolbachia_phage	5.1e-48	80.6
WP_015587741.1\|132403_133438_-	S49 family peptidase	F8QZT1	Wolbachia_phage	1.2e-163	89.3
WP_015587742.1\|134846_135071_-\|head	phage head stabilizing protein GpW	A0A1B2LRU7	Wolbachia_phage	2.4e-29	86.5
WP_015587743.1\|135063_136893_-\|terminase	phage terminase large subunit family protein	A0A1B2LRQ2	Wolbachia_phage	0.0e+00	95.9
WP_015587744.1\|136889_138374_-	ankyrin repeat domain-containing protein	F8QZT5	Wolbachia_phage	6.4e-203	89.3
WP_015587745.1\|138392_138863_-	hypothetical protein	A0A1B2LRT3	Wolbachia_phage	2.9e-61	84.0
WP_015587746.1\|138998_139469_-	hypothetical protein	E9P621	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	8.3e-64	75.5
WP_015587749.1\|140187_140679_+	sigma-70 family RNA polymerase sigma factor	A0A1B2LRS7	Wolbachia_phage	4.3e-31	50.3
WP_015587750.1\|140728_141526_+	ATP-binding protein	E9P631	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	2.4e-124	81.0
WP_015587703.1\|141832_142852_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_015587751.1\|142867_143356_+	hypothetical protein	A0A1B2LRU0	Wolbachia_phage	7.0e-58	68.7
WP_015587752.1\|143352_144579_+	AAA family ATPase	A0A1B2LRQ9	Wolbachia_phage	1.2e-141	63.7
WP_015587753.1\|144594_146601_+	AAA family ATPase	Q9JMN6	Wolbachia_phage	1.0e-256	77.0
WP_015587754.1\|146613_147723_-	hypothetical protein	Q9JMN2	Wolbachia_phage	1.7e-131	61.5
WP_015587755.1\|147688_148885_-	hypothetical protein	Q9JMN1	Wolbachia_phage	8.6e-150	64.1
WP_081600811.1\|149226_150300_+	recombinase family protein	A0A1B2LRQ3	Wolbachia_phage	1.7e-104	57.0
WP_051063871.1\|151665_152175_+	hypothetical protein	NA	NA	NA	NA
WP_041581309.1\|152232_152490_+	hypothetical protein	NA	NA	NA	NA
WP_015587756.1\|152614_153205_-	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_015587757.1\|153201_154386_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_015587758.1\|154500_155058_+	hypothetical protein	NA	NA	NA	NA
WP_015587759.1\|155031_155931_-	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_015587760.1\|155921_156800_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_015587761.1\|157388_158903_+	protein translocase subunit SecD	NA	NA	NA	NA
WP_135352730.1\|159437_159689_+\|transposase	transposase	NA	NA	NA	NA
WP_081600812.1\|159879_160008_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_015587762.1\|160230_161172_-	P44/Msp2 family outer membrane protein	NA	NA	NA	NA
WP_015587763.1\|161231_162458_-\|tRNA	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase MtaB	NA	NA	NA	NA

DBSCAN-SWA_2

587241 : 595105

Wolbachia_phage(62.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015588086.1\|587241_588483_-	IscS subfamily cysteine desulfurase	H7BUW1	unidentified_phage	3.6e-34	37.9
WP_015588087.1\|588814_589474_+	RadC family protein	A0A1B2LRS6	Wolbachia_phage	8.7e-43	40.3
WP_015588088.1\|589576_589906_+	helix-turn-helix transcriptional regulator	A0A1B2LRR7	Wolbachia_phage	8.2e-10	36.5
WP_015588089.1\|589928_590291_+	helix-turn-helix transcriptional regulator	A0A1B2LRS2	Wolbachia_phage	2.6e-09	31.4
WP_015588090.1\|590471_591545_-	hypothetical protein	A0A1B2LRQ6	Wolbachia_phage	1.0e-53	41.6
WP_041581483.1\|591743_592667_+	hypothetical protein	NA	NA	NA	NA
WP_007549995.1\|592710_593040_+	helix-turn-helix transcriptional regulator	E9P644	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.1e-06	31.7
WP_015588092.1\|593062_593425_+	helix-turn-helix transcriptional regulator	A0A1B2LRR8	Wolbachia_phage	1.0e-08	34.3
WP_179943657.1\|593834_594005_+	hypothetical protein	NA	NA	NA	NA
WP_015587822.1\|594139_595105_-\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	9.5e-14	25.1

DBSCAN-SWA_3

629747 : 691371

Bacillus_phage(13.33%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015587703.1\|629747_630767_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_129827318.1\|630883_630985_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_015588124.1\|631272_632292_-	Mrp/NBP35 family ATP-binding protein	NA	NA	NA	NA
WP_015588125.1\|632371_633034_+	hypothetical protein	NA	NA	NA	NA
WP_015588021.1\|633152_634700_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	4.3e-133	50.4
WP_015588126.1\|635389_636463_-	AI-2E family transporter	NA	NA	NA	NA
WP_041581498.1\|636512_637082_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_015588128.1\|637505_638711_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_015588129.1\|638795_639662_-	ParB/RepB/Spo0J family partition protein	S5VTK0	Leptospira_phage	1.2e-15	30.8
WP_015588130.1\|639658_640501_-	ParA family protein	Q8JL10	Natrialba_phage	5.5e-18	31.6
WP_015588131.1\|640587_643068_-	response regulator	B5LWN8	Feldmannia_species_virus	9.3e-05	31.7
WP_015588132.1\|643227_644052_+	oxygen-dependent coproporphyrinogen oxidase	NA	NA	NA	NA
WP_015588133.1\|645445_646141_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_015588134.1\|646535_646736_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_015588135.1\|646766_647927_+	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_015588136.1\|647930_648812_+	succinate--CoA ligase subunit alpha	A0A2K9L1S3	Tupanvirus	3.8e-17	29.5
WP_010403976.1\|648818_649613_-	diaminopimelate epimerase	NA	NA	NA	NA
WP_015588137.1\|649718_650831_+	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_015588138.1\|650806_651379_-	nitroreductase family protein	NA	NA	NA	NA
WP_015588139.1\|651475_652003_+	biotin transporter BioY	NA	NA	NA	NA
WP_015588140.1\|651999_652398_+	DUF1284 domain-containing protein	NA	NA	NA	NA
WP_015588141.1\|652466_653333_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015588142.1\|653521_656224_+	DNA topoisomerase (ATP-hydrolyzing) subunit A	G3M9Z5	Bacillus_virus	5.1e-89	31.9
WP_015588143.1\|656318_656918_+	ubiquinol-cytochrome c reductase iron-sulfur subunit	NA	NA	NA	NA
WP_041581501.1\|657388_657631_-	hypothetical protein	NA	NA	NA	NA
WP_051063876.1\|658046_658304_-\|transposase	transposase	NA	NA	NA	NA
WP_015588144.1\|658951_660382_-\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_015588145.1\|660590_661064_+	hypothetical protein	NA	NA	NA	NA
WP_135352772.1\|661479_661620_+	hypothetical protein	NA	NA	NA	NA
WP_015588146.1\|661848_662769_+	molecular chaperone DnaJ	NA	NA	NA	NA
WP_015588147.1\|662756_664055_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_015588148.1\|664051_664636_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_015588149.1\|664930_665392_+	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
WP_015588150.1\|665445_666138_+	DsbA family protein	NA	NA	NA	NA
WP_015588151.1\|666166_666445_-	DUF2671 domain-containing protein	NA	NA	NA	NA
WP_006013497.1\|666695_667373_+	O-methyltransferase	A0A2P1JQT7	Mycobacterium_phage	1.7e-17	32.1
WP_015588152.1\|667344_667998_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_015588153.1\|667994_668375_-	hypothetical protein	NA	NA	NA	NA
WP_015588154.1\|668547_670131_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	5.1e-41	36.5
WP_006013488.1\|670152_670467_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_015588156.1\|670803_671490_+	P44/Msp2 family outer membrane protein	NA	NA	NA	NA
WP_015588157.1\|671773_672667_+	RNA polymerase factor sigma-32	A0A248SJA5	Salicola_phage	1.2e-26	29.0
WP_015588158.1\|672659_673157_+	hypothetical protein	NA	NA	NA	NA
WP_015588159.1\|673268_674408_+	DNA polymerase III subunit beta	R9TRR6	Rhizobium_phage	1.9e-53	35.7
WP_015588160.1\|674409_675147_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_015588161.1\|675266_676334_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.9e-116	61.9
WP_015588162.1\|676368_676932_-\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_015588163.1\|676931_677543_-	50S ribosomal protein L25/general stress protein Ctc	NA	NA	NA	NA
WP_015588164.1\|677685_677985_+	ETC complex I subunit	NA	NA	NA	NA
WP_015588165.1\|678977_679916_-	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_015588166.1\|680121_681333_+	MFS transporter	Q6JIH2	Burkholderia_virus	4.8e-47	33.3
WP_015588167.1\|681363_682146_-	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_015588168.1\|682264_683503_-	cell division protein FtsA	NA	NA	NA	NA
WP_015588169.1\|683633_684173_+	peptide deformylase	E3SLL2	Synechococcus_phage	3.4e-21	39.4
WP_015588170.1\|684162_684945_+	uracil-DNA glycosylase	A0A127AW33	Bacillus_phage	1.1e-12	30.2
WP_015588171.1\|685391_685919_+	demethoxyubiquinone hydroxylase family protein	NA	NA	NA	NA
WP_015587703.1\|686323_687343_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_051063878.1\|687441_689535_-	collagen-like protein	NA	NA	NA	NA
WP_015588172.1\|689907_691371_-\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	2.1e-20	26.9

DBSCAN-SWA_4

741592 : 869503

115

Wolbachia_phage(34.38%)

transposase,protease,tail,terminase,plate,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015588215.1\|741592_743701_+\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_015588216.1\|743684_745502_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_015588217.1\|745513_746005_-	Smr/MutS family protein	NA	NA	NA	NA
WP_015588218.1\|746097_746865_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_015588219.1\|747344_748301_-	hypothetical protein	NA	NA	NA	NA
WP_041581343.1\|748699_748897_-	hypothetical protein	NA	NA	NA	NA
WP_015587703.1\|751030_752050_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_015588220.1\|752867_753185_+	ribosome silencing factor	NA	NA	NA	NA
WP_015588221.1\|753415_754678_+\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	9.4e-62	34.0
WP_041581520.1\|754780_755524_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015588223.1\|757509_758055_-	hypothetical protein	NA	NA	NA	NA
WP_015588021.1\|758698_760246_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	4.3e-133	50.4
WP_167470140.1\|760242_760404_+	hypothetical protein	NA	NA	NA	NA
WP_015588224.1\|760422_761058_+	chromosomal DNA replication initiator DnaA	NA	NA	NA	NA
WP_015588226.1\|761429_762416_+	tyrosine recombinase XerD	A0A0F7LBR0	Escherichia_phage	1.3e-10	29.6
WP_015588227.1\|762472_763198_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_015588228.1\|763241_763511_+	30S ribosomal protein S20	NA	NA	NA	NA
WP_015588229.1\|763590_764832_+	citrate synthase	NA	NA	NA	NA
WP_015588230.1\|764872_766303_-	hypothetical protein	NA	NA	NA	NA
WP_041581345.1\|766329_766509_-	hypothetical protein	NA	NA	NA	NA
WP_015588231.1\|766888_767182_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_135352801.1\|767302_767359_-	hypothetical protein	NA	NA	NA	NA
WP_015588232.1\|767714_768935_-	hypothetical protein	NA	NA	NA	NA
WP_015588233.1\|769203_770193_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.4e-07	29.1
WP_015588234.1\|770189_770762_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_015588235.1\|771054_771579_+	cytochrome c family protein	NA	NA	NA	NA
WP_015588236.1\|771580_772336_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_015588237.1\|772379_774296_-	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	5.1e-112	37.7
WP_015588238.1\|774424_774853_-	hypothetical protein	NA	NA	NA	NA
WP_015588239.1\|775040_775628_+	NADH-quinone oxidoreductase subunit J	NA	NA	NA	NA
WP_015588240.1\|775618_775927_+	NADH-quinone oxidoreductase subunit NuoK	NA	NA	NA	NA
WP_015588241.1\|775931_777779_+	NADH-quinone oxidoreductase subunit L	NA	NA	NA	NA
WP_015588242.1\|777782_779225_+	NADH-quinone oxidoreductase subunit M	NA	NA	NA	NA
WP_015588243.1\|779221_780607_+	NADH-quinone oxidoreductase subunit N	NA	NA	NA	NA
WP_015588244.1\|780611_781616_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_015588246.1\|781733_782126_+	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_015588247.1\|782201_782654_-	hypothetical protein	NA	NA	NA	NA
WP_015588248.1\|782699_784103_-	MgtE intracellular N domain protein	NA	NA	NA	NA
WP_015588249.1\|784763_786029_+	NADH-quinone oxidoreductase subunit NuoF	NA	NA	NA	NA
WP_015588250.1\|786034_786553_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	7.1e-08	28.5
WP_015588251.1\|786565_788467_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	4.6e-129	40.5
WP_015588252.1\|788652_789135_-	NADH-quinone oxidoreductase subunit NuoI	NA	NA	NA	NA
WP_015588253.1\|789338_790667_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_015588254.1\|790970_791981_+	NAD(P)/FAD-dependent oxidoreductase	G3MA85	Bacillus_virus	1.3e-21	28.4
WP_015587703.1\|793093_794113_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_015588255.1\|795618_797004_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.2e-54	31.4
WP_135353031.1\|797218_797599_+	hypothetical protein	NA	NA	NA	NA
WP_015588256.1\|797807_798146_-	TrbC/VirB2 family protein	NA	NA	NA	NA
WP_015588257.1\|798274_799090_+	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_015588258.1\|799076_799841_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	7.8e-11	28.8
WP_015588259.1\|799957_803332_+	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_007302306.1\|803602_803950_+	diacylglycerol kinase	NA	NA	NA	NA
WP_179943662.1\|803956_804904_-	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	9.0e-09	30.3
WP_015588261.1\|804909_806718_-	hypothetical protein	NA	NA	NA	NA
WP_015587822.1\|806935_807901_-\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	9.5e-14	25.1
WP_015588262.1\|808943_809198_-\|tail	phage tail assembly protein	A0A1B2LRV6	Wolbachia_phage	4.2e-22	68.2
WP_015588263.1\|809331_810072_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	E9P639	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	4.7e-98	88.3
WP_015588021.1\|810068_811616_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	4.3e-133	50.4
WP_015588264.1\|812672_812978_+	hypothetical protein	Q9JMM1	Wolbachia_phage	1.3e-41	79.2
WP_015588265.1\|812978_813467_+\|tail	phage tail protein	A0A1B2LRS9	Wolbachia_phage	1.7e-64	85.1
WP_015588266.1\|813476_813959_+	hypothetical protein	A0A1B2LRU9	Wolbachia_phage	3.1e-66	79.3
WP_015588267.1\|813945_814410_+\|plate	phage baseplate assembly protein V	Q9JML8	Wolbachia_phage	4.6e-75	90.3
WP_015588268.1\|814406_814661_+	PAAR domain-containing protein	Q75QM1	Wolbachia_phage	3.6e-13	62.5
WP_015588269.1\|814663_814999_+	GPW/gp25 family protein	E9P610	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	7.2e-46	85.6
WP_015588270.1\|815001_815802_+\|plate	baseplate J/gp47 family protein	A0A1B2LRR9	Wolbachia_phage	9.0e-119	87.5
WP_015588271.1\|815801_816962_+\|tail	phage tail protein	Q9JML5	Wolbachia_phage	7.2e-210	91.4
WP_015588272.1\|817130_817832_+	ankyrin repeat domain-containing protein	A0A1B2LRT4	Wolbachia_phage	1.5e-77	82.4
WP_015588273.1\|817870_818341_+	ankyrin repeat domain-containing protein	A0A1B2LRV4	Wolbachia_phage	3.9e-29	86.5
WP_017532679.1\|818439_818715_+	hypothetical protein	A0A1B2LRU8	Wolbachia_phage	3.3e-44	98.9
WP_015587703.1\|819499_820519_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_015588274.1\|820707_821196_+	RNA pyrophosphohydrolase	NA	NA	NA	NA
WP_015588275.1\|821185_821974_+	TatD family hydrolase	NA	NA	NA	NA
WP_015588276.1\|821979_822924_-	malate dehydrogenase	NA	NA	NA	NA
WP_015588277.1\|822927_823503_-	NADH-quinone oxidoreductase subunit C	NA	NA	NA	NA
WP_015588278.1\|823504_824008_-	NADH-quinone oxidoreductase subunit B	NA	NA	NA	NA
WP_015588279.1\|823998_824352_-	NADH-quinone oxidoreductase subunit A	NA	NA	NA	NA
WP_015588280.1\|824369_824738_-	HIT domain-containing protein	NA	NA	NA	NA
WP_041581354.1\|824744_825026_-	hypothetical protein	NA	NA	NA	NA
WP_015588282.1\|825029_825764_-	hypothetical protein	NA	NA	NA	NA
WP_015588283.1\|825948_827325_+	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_015588284.1\|827373_828324_+	complex I NDUFA9 subunit family protein	NA	NA	NA	NA
WP_015588285.1\|828548_829505_-	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_015588286.1\|829497_830535_-	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_006014434.1\|830543_830726_-	50S ribosomal protein L32	NA	NA	NA	NA
WP_012481974.1\|830957_831740_+	ABC transporter permease	NA	NA	NA	NA
WP_015588287.1\|831732_832434_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.6e-25	36.2
WP_015588288.1\|832713_834057_-	signal recognition particle protein	NA	NA	NA	NA
WP_015588289.1\|834041_835601_-	oxidoreductase	NA	NA	NA	NA
WP_015588290.1\|835904_838715_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_015588291.1\|838745_839192_-	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_015588292.1\|839196_839757_-	OmpH family outer membrane protein	NA	NA	NA	NA
WP_015588293.1\|839757_842091_-	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_015588294.1\|842098_843214_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_010404229.1\|843313_843580_+	succinate dehydrogenase assembly factor 2	NA	NA	NA	NA
WP_010404232.1\|843557_843875_-	cell division protein ZapA	NA	NA	NA	NA
WP_015588295.1\|843918_844197_-	integration host factor subunit beta	NA	NA	NA	NA
WP_015588296.1\|844216_845869_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_015588297.1\|845972_846617_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_167470134.1\|846657_846849_-	hypothetical protein	NA	NA	NA	NA
WP_015588298.1\|846824_847346_-	hypothetical protein	A0A1Z1LWI6	Synechococcus_phage	2.3e-22	36.0
WP_015588299.1\|847476_848874_-\|terminase	phage terminase large subunit	W8CPK4	Croceibacter_phage	3.8e-48	31.6
WP_015588300.1\|848943_850023_+	hypothetical protein	NA	NA	NA	NA
WP_015587703.1\|850420_851440_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_015588301.1\|853268_853712_-	hypothetical protein	NA	NA	NA	NA
WP_015588302.1\|853717_854089_-	DnaJ domain-containing protein	A0A1V0SIM1	Klosneuvirus	3.1e-05	49.1
WP_015588303.1\|854884_855781_+	cation diffusion facilitator family transporter	A0A1V0SED0	Indivirus	2.0e-13	31.5
WP_041581530.1\|857701_858274_-	glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_015588305.1\|858287_859754_-	amino acid carrier protein	NA	NA	NA	NA
WP_015588306.1\|859756_861091_-	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_015588307.1\|861099_861885_-	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_015588308.1\|861881_862565_-	phosphatidylserine decarboxylase	NA	NA	NA	NA
WP_041581364.1\|863700_863937_+	hypothetical protein	NA	NA	NA	NA
WP_015588310.1\|864024_865260_+	hypothetical protein	NA	NA	NA	NA
WP_015588311.1\|865478_867851_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	3.2e-111	34.6
WP_041581365.1\|868036_869503_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA

DBSCAN-SWA_5

930283 : 992675

Wolbachia_phage(38.89%)

protease,portal,head,terminase,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015588369.1\|930283_931573_+\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_006012302.1\|931574_931910_-	TrbC/VirB2 family protein	NA	NA	NA	NA
WP_006012309.1\|932005_932740_-	3-oxoacyl-[acyl-carrier-protein] reductase	F2NZ40	Diadromus_pulchellus_ascovirus	2.6e-11	27.5
WP_167470139.1\|932856_933000_-	hypothetical protein	NA	NA	NA	NA
WP_015588370.1\|933252_933729_+\|transposase	transposase	NA	NA	NA	NA
WP_007301972.1\|933836_934193_+\|transposase	transposase	NA	NA	NA	NA
WP_041581367.1\|934498_937168_+	pyruvate, phosphate dikinase	A0A2I7QIA2	Vibrio_phage	3.8e-89	38.8
WP_015588372.1\|937325_938609_+	hypothetical protein	NA	NA	NA	NA
WP_041581368.1\|939027_939291_-	hypothetical protein	NA	NA	NA	NA
WP_179943653.1\|939555_940590_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_015588374.1\|940726_941050_-	Grx4 family monothiol glutaredoxin	NA	NA	NA	NA
WP_006012412.1\|941066_941285_-	BolA/IbaG family iron-sulfur metabolism protein	NA	NA	NA	NA
WP_015588375.1\|941323_942643_-	NADP-dependent malic enzyme	NA	NA	NA	NA
WP_015588376.1\|942762_943305_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_015588377.1\|943405_944404_+	hypothetical protein	NA	NA	NA	NA
WP_015588378.1\|944471_945158_+	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_015588379.1\|945165_945906_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_015588380.1\|945902_946952_+	M23 family metallopeptidase	A0A292GJG6	Xanthomonas_phage	3.0e-21	45.2
WP_015588381.1\|946935_947805_+	SPFH domain-containing protein	NA	NA	NA	NA
WP_015588382.1\|947974_948259_+	Putative PQ loop repeat protein	NA	NA	NA	NA
WP_015588383.1\|948230_948911_+	thiamine diphosphokinase	NA	NA	NA	NA
WP_015588384.1\|949636_950674_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015588385.1\|950622_951081_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_051063880.1\|951159_952308_-	Bcr/CflA family efflux MFS transporter	NA	NA	NA	NA
WP_015588387.1\|952457_953156_+	bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE	NA	NA	NA	NA
WP_015588388.1\|953330_955028_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.8e-53	30.3
WP_015588389.1\|955763_956348_+	hypothetical protein	NA	NA	NA	NA
WP_015588391.1\|957823_959530_+\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_015588392.1\|959545_960169_-	heme ABC exporter ATP-binding protein CcmA	NA	NA	NA	NA
WP_015588393.1\|960172_960604_-	hypothetical protein	NA	NA	NA	NA
WP_010404879.1\|963155_963563_-	nucleoside deaminase	NA	NA	NA	NA
WP_015588395.1\|963903_965511_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	6.4e-148	49.6
WP_007302593.1\|965510_965831_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_015588396.1\|965946_966471_+	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_015588397.1\|966460_967501_-	hypothetical protein	NA	NA	NA	NA
WP_015588398.1\|967725_968472_-	hypothetical protein	NA	NA	NA	NA
WP_015588399.1\|969095_970907_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7J689	Paramecium_bursaria_Chlorella_virus	2.1e-91	36.6
WP_015588400.1\|970915_971329_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	2.9e-12	46.9
WP_015588401.1\|971717_972533_+	30S ribosomal protein S2	NA	NA	NA	NA
WP_041581370.1\|972529_973375_+	elongation factor Ts	NA	NA	NA	NA
WP_015588403.1\|973358_974102_+	UMP kinase	NA	NA	NA	NA
WP_015588404.1\|974109_974667_+	ribosome recycling factor	NA	NA	NA	NA
WP_015588405.1\|974860_975877_+	substrate-binding domain-containing protein	A0A1B1IWY0	uncultured_Mediterranean_phage	4.6e-59	40.3
WP_015588407.1\|977438_978896_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_015588408.1\|978967_979525_+	dCTP deaminase	S5VM63	Pseudomonas_phage	4.4e-56	61.5
WP_015588409.1\|979530_980544_-	hypothetical protein	NA	NA	NA	NA
WP_015588021.1\|980774_982322_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	4.3e-133	50.4
WP_015588410.1\|984426_984882_+	hypothetical protein	Q9JMN0	Wolbachia_phage	1.8e-76	92.7
WP_015588411.1\|984985_986191_+	DNA modification methylase	E9P620	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	4.1e-224	93.3
WP_015588412.1\|986206_986686_+	hypothetical protein	Q9JMM9	Wolbachia_phage	2.5e-76	96.9
WP_015588413.1\|986689_988165_+	ankyrin repeat domain-containing protein	F8QZT7	Wolbachia_phage	8.0e-214	82.6
WP_015588414.1\|988161_989991_+\|terminase	phage terminase large subunit family protein	A0A1B2LRQ2	Wolbachia_phage	0.0e+00	95.2
WP_015588415.1\|989992_990208_+\|head	phage head stabilizing protein GpW	A0A1B2LRU7	Wolbachia_phage	3.2e-23	81.1
WP_015588416.1\|990237_991269_+	DUF1016 family protein	Q9JMP5	Wolbachia_phage	1.1e-166	84.0
WP_015588417.1\|991268_992675_+\|portal	phage portal protein	A0A1B2LRR5	Wolbachia_phage	3.9e-266	96.6

DBSCAN-SWA_6

1051301 : 1199349

Wolbachia_phage(54.76%)

transposase,protease,head,tail,plate,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015588460.1\|1051301_1052321_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_015588461.1\|1052357_1052741_-	TraR/DksA C4-type zinc finger protein	NA	NA	NA	NA
WP_015588462.1\|1052849_1053497_+	heme exporter protein CcmB	NA	NA	NA	NA
WP_015588463.1\|1053673_1054384_-	class II aldolase/adducin family protein	NA	NA	NA	NA
WP_015588464.1\|1054619_1055201_+	hypothetical protein	NA	NA	NA	NA
WP_015588465.1\|1055173_1055782_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_015588466.1\|1055781_1056915_-	cation:dicarboxylase symporter family transporter	NA	NA	NA	NA
WP_015588467.1\|1057022_1058189_-	multifunctional ribose 5-phosphate isomerase B/3-demethylubiquinone-9 3-methyltransferase/2-octaprenyl-6-hydroxy phenol methylase	A0A2K9L4K8	Tupanvirus	4.7e-07	33.9
WP_015588468.1\|1058334_1060077_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	2.1e-59	34.3
WP_041581389.1\|1060196_1061480_+	sodium:proton antiporter	NA	NA	NA	NA
WP_015588470.1\|1061746_1063501_+	DnaJ domain-containing protein	A0A1V0SE10	Indivirus	7.0e-07	40.7
WP_015588471.1\|1063738_1064086_+	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_015588472.1\|1064093_1065107_+	hypothetical protein	NA	NA	NA	NA
WP_015588473.1\|1065090_1065492_+	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_015588474.1\|1065551_1068821_-	UvrD-helicase domain-containing protein	G3MA40	Bacillus_virus	1.6e-12	24.7
WP_015588475.1\|1068895_1069762_+	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_007302686.1\|1069765_1070113_+	Mth938-like domain-containing protein	NA	NA	NA	NA
WP_015588476.1\|1070106_1070916_+	metal ABC transporter permease	NA	NA	NA	NA
WP_015588477.1\|1071029_1071212_+	hypothetical protein	NA	NA	NA	NA
WP_015588478.1\|1071217_1072237_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_015588479.1\|1072467_1073802_-\|tRNA	glutamate--tRNA ligase	A0A2K9L0I5	Tupanvirus	1.7e-13	34.9
WP_015588480.1\|1074027_1075857_+	translational GTPase TypA	E4ZFJ7	Streptococcus_phage	8.0e-22	40.8
WP_041581561.1\|1076190_1077426_+\|tRNA	CCA tRNA nucleotidyltransferase	A0A2L0UZ92	Agrobacterium_phage	2.8e-50	34.2
WP_015588484.1\|1079821_1080355_-\|head,protease	HK97 family phage prohead protease	Q8W628	Enterobacteria_phage	2.1e-31	43.9
WP_015588485.1\|1081101_1081461_-	hypothetical protein	NA	NA	NA	NA
WP_015588486.1\|1081612_1082584_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_015588487.1\|1082587_1083343_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	5.4e-49	43.7
WP_041581392.1\|1083460_1083778_+	hypothetical protein	NA	NA	NA	NA
WP_015588488.1\|1085441_1087952_+	DNA mismatch repair protein MutS	A0A2H4UUR2	Bodo_saltans_virus	8.7e-35	22.5
WP_015588489.1\|1088013_1089378_-	ankyrin repeat domain-containing protein	M1IFK5	Paramecium_bursaria_Chlorella_virus	5.8e-09	25.9
WP_015588490.1\|1089511_1091314_+\|tRNA	aspartate--tRNA ligase	A0A1V0SIS0	Klosneuvirus	9.4e-07	22.6
WP_015588491.1\|1091349_1092612_+	MFS transporter	Q6JIH2	Burkholderia_virus	8.3e-34	25.4
WP_015588492.1\|1092619_1093543_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_015588493.1\|1093657_1096030_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015588494.1\|1096203_1097490_+	Na+/H+ antiporter	NA	NA	NA	NA
WP_099046259.1\|1097664_1098766_-	peptide chain release factor 2	NA	NA	NA	NA
WP_015588496.1\|1098921_1100292_+	magnesium transporter	NA	NA	NA	NA
WP_015588460.1\|1102552_1103572_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_015588497.1\|1103587_1103959_+\|head	head decoration protein	Q9JMM3	Wolbachia_phage	4.7e-54	90.2
WP_015588498.1\|1105140_1105476_+	GPW/gp25 family protein	Q75QM0	Wolbachia_phage	9.4e-54	95.5
WP_015588499.1\|1105485_1106283_+\|plate	baseplate J/gp47 family protein	Q75QL9	Wolbachia_phage	4.6e-139	96.2
WP_015588500.1\|1106289_1107507_+\|tail	phage tail protein	A0A1B2LRQ8	Wolbachia_phage	2.1e-135	60.1
WP_015588501.1\|1107528_1108215_+	hypothetical protein	Q75QL7	Wolbachia_phage	1.2e-119	95.6
WP_015588502.1\|1108231_1110157_+	DUF4815 domain-containing protein	A0A1B2LRP5	Wolbachia_phage	0.0e+00	92.1
WP_015588503.1\|1110170_1111358_+	hypothetical protein	A0A1B2LRR4	Wolbachia_phage	2.7e-204	90.2
WP_015588504.1\|1111362_1111548_+	hypothetical protein	A0A1B2LRW5	Wolbachia_phage	1.2e-18	73.4
WP_015588505.1\|1111544_1113020_+	hypothetical protein	Q75QL4	Wolbachia_phage	1.4e-162	77.2
WP_015588506.1\|1113026_1113584_+	hypothetical protein	Q75QL3	Wolbachia_phage	1.5e-43	53.0
WP_015588507.1\|1113595_1114753_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A1B2LRR3	Wolbachia_phage	1.7e-195	87.8
WP_015588508.1\|1114767_1115268_+\|tail	phage major tail tube protein	Q75QK9	Wolbachia_phage	1.0e-83	91.6
WP_015588509.1\|1115284_1115536_+\|tail	phage tail assembly protein	Q75QK8	Wolbachia_phage	1.3e-36	98.8
WP_015588510.1\|1117822_1118245_+\|tail	phage tail protein	A0A1B2LRV9	Wolbachia_phage	1.8e-25	46.6
WP_015588511.1\|1118222_1118429_+\|tail	tail protein X	A0A1B2LRT9	Wolbachia_phage	1.5e-17	60.9
WP_015588512.1\|1118430_1119411_+	phage late control protein GpD	A0A1B2LRT8	Wolbachia_phage	3.0e-92	55.1
WP_015588513.1\|1119376_1119913_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015588514.1\|1120037_1120256_+	hypothetical protein	A0A1B2LRU2	Wolbachia_phage	1.2e-09	55.2
WP_015588515.1\|1120260_1121178_+	patatin-like phospholipase family protein	A0A1B2LRS3	Wolbachia_phage	7.9e-135	78.2
WP_015588516.1\|1121334_1128558_+	SpvB and TcdB toxin domain protein	S5W9C6	Leptospira_phage	3.8e-06	35.2
WP_015588517.1\|1128802_1129171_+	hypothetical protein	NA	NA	NA	NA
WP_015588518.1\|1129172_1138310_+	hypothetical protein	NA	NA	NA	NA
WP_015588519.1\|1138321_1147921_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015588520.1\|1148243_1148654_-	helix-turn-helix transcriptional regulator	A0A1B2LRR8	Wolbachia_phage	1.3e-09	35.1
WP_015588521.1\|1148688_1149021_-	helix-turn-helix transcriptional regulator	A0A1B2LRS2	Wolbachia_phage	4.4e-11	42.2
WP_006012372.1\|1149130_1149790_-	DNA repair protein RadC	A0A1B2LRS6	Wolbachia_phage	1.0e-43	41.2
WP_167537174.1\|1149782_1149956_-	hypothetical protein	NA	NA	NA	NA
WP_015588523.1\|1151024_1152980_+	NAD-dependent DNA ligase LigA	A0A1W6DX16	Sphingobium_phage	7.6e-103	38.2
WP_015588524.1\|1154155_1154482_+	hypothetical protein	NA	NA	NA	NA
WP_015588525.1\|1154498_1157507_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015588526.1\|1157640_1158399_-	FtsQ-type POTRA domain-containing protein	NA	NA	NA	NA
WP_015588527.1\|1158379_1159333_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_015588528.1\|1159905_1160172_+	hypothetical protein	NA	NA	NA	NA
WP_015588529.1\|1160210_1160585_-	ferredoxin family protein	NA	NA	NA	NA
WP_015588530.1\|1160646_1161732_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	4.8e-30	35.2
WP_010405218.1\|1161996_1162137_+	hypothetical protein	NA	NA	NA	NA
WP_135352730.1\|1162820_1163072_+\|transposase	transposase	NA	NA	NA	NA
WP_179943654.1\|1163202_1165800_-	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_015588532.1\|1166079_1167066_+	hypothetical protein	NA	NA	NA	NA
WP_015588533.1\|1167275_1168079_+	hypothetical protein	NA	NA	NA	NA
WP_015588534.1\|1168179_1169340_+	porin	NA	NA	NA	NA
WP_015588535.1\|1169595_1170936_+	DNA recombination protein RmuC	NA	NA	NA	NA
WP_015588536.1\|1170968_1172075_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	1.8e-45	37.7
WP_015588537.1\|1172939_1173620_+	DNA repair protein RadC	A0A1B2LRS6	Wolbachia_phage	1.0e-46	43.2
WP_015588538.1\|1173832_1175074_-	hypothetical protein	NA	NA	NA	NA
WP_015588539.1\|1175220_1177302_+	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_015588541.1\|1179015_1179615_+	peroxiredoxin	NA	NA	NA	NA
WP_015588542.1\|1179601_1180549_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	4.5e-69	46.2
WP_015588543.1\|1182803_1183349_-	hypothetical protein	NA	NA	NA	NA
WP_041581408.1\|1183618_1183819_-	hypothetical protein	NA	NA	NA	NA
WP_041581571.1\|1183860_1186104_-	hypothetical protein	Q9JML0	Wolbachia_phage	1.6e-19	24.4
WP_015588545.1\|1190313_1197582_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015588546.1\|1197683_1198223_+	latrotoxin-related protein	NA	NA	NA	NA
WP_015588547.1\|1198590_1199349_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	E9P639	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.0e-87	80.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_021084

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection