CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_021174	Burkholderia thailandensis MSMB121 chromosome 2, complete sequence	2 crisprs	cas3,csa3,DinG	1	1	1	0
NC_021173	Burkholderia thailandensis MSMB121 chromosome 1, complete sequence	1 crisprs	cas3,DEDDh,csa3,DinG	0	1	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_021174_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021174_1

275871-275962

Orphan

Consensus_repeat	Method
GCGACGCGCGCAAGGCCGAAGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021174_1

>merge|NC_021174|1|275871-275962|CRISPRCasFinder
GCGACGCGCGCAAGGCCGAAGCGGGCACGAAGCGCGCGACCGACGACGACAAGCACCGCAAGCACGACGGCGACGCGCGCAAGGCGGAAGCG

>NC_021174|1|1|275871-275962|CRISPRCasFinder
GCGACGCGCGCAAGGCCGAAGCG	GGCACGAAGCGCGCGACCGACGACGACAAGCACCGCAAGCACGACG
GCGACGCGCGCAAGGCGGAAGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_021174.1\|WP_015603646.1\|281674_283150_+\|calcineurin-like-phosphoesterase	unknown	unknown	gnl\|CDD\|277318
NC_021174.1\|WP_015603385.1\|283146_284703_+\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|224771
NC_021174.1\|WP_075645108.1\|270169_271270_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|275336
NC_021174.1\|WP_096746675.1\|276934_278290_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NC_021174.1\|WP_015603666.1\|274738_275248_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|183009
NC_021174.1\|WP_006027011.1\|286323_287892_+\|tyrosinase-family-protein	unknown	unknown	gnl\|CDD\|365987
NC_021174.1\|WP_015603895.1\|278397_279123_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NC_021174.1\|WP_015603828.1\|279211_280543_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NC_021174.1\|WP_015603150.1\|273527_274544_-\|1-aminocyclopropane-1-carboxylate-deaminase	unknown	unknown	gnl\|CDD\|183494
NC_021174.1\|WP_015603364.1\|266341_267061_-\|alanyl-tRNA-editing-protein	unknown	unknown	gnl\|CDD\|225427
NC_021174.1\|WP_006027026.1\|268953_269250_-\|DUF1330-domain-containing-protein	unknown	unknown	gnl\|CDD\|377765
NC_021174.1\|WP_006027012.1\|284873_285734_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|377216
NC_021174.1\|WP_015603742.1\|271946_272807_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_021174.1\|WP_155246037.1\|271392_271959_+\|hypothetical-protein	unknown	unknown	unknown
NC_021174.1\|WP_009915228.1\|269310_270114_-\|hypothetical-protein	unknown	unknown	unknown
NC_021174.1\|WP_015603240.1\|273021_273495_-\|hypothetical-protein	unknown	unknown	unknown
NC_021174.1\|WP_015602972.1\|280592_281501_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|226145
NC_021174.1\|WP_015604115.1\|287906_288680_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378321
NC_021174.1\|WP_015604122.1\|289094_289367_+\|hypothetical-protein	unknown	unknown	unknown
NC_021174.1\|WP_015602484.1\|267396_268890_-\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|178402

Protein	Function_ID	Function_description	E-value
NC_021174.1\|WP_015603646.1\|281674_283150_+\|calcineurin-like-phosphoesterase	gnl\|CDD\|277318	cd00839, MPP_PAPs, purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain. Purple acid phosphatases (PAPs) belong to a diverse family of binuclear metallohydrolases that have been identified and characterized in plants, animals, and fungi. PAPs contain a binuclear metal center and their characteristic pink or purple color derives from a charge-transfer transition between a tyrosine residue and a chromophoric ferric ion within the binuclear center. PAPs catalyze the hydrolysis of a wide range of activated phosphoric acid mono- and di-esters and anhydrides. PAPs are distinguished from the other phosphatases by their insensitivity to L-(+) tartrate inhibition and are therefore also known as tartrate resistant acid phosphatases (TRAPs). While only a few copies of PAP-like genes are present in mammalian and fungal genomes, multiple copies are present in plant genomes. PAPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.26528e-08
NC_021174.1\|WP_006027012.1\|284873_285734_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|377216	pfam04072, LCM, Leucine carboxyl methyltransferase. Family of leucine carboxyl methyltransferases EC:2.1.1.-. This family may need divides a the full alignment contains a significantly shorter mouse sequence.	8.58721e-51
NC_021174.1\|WP_075645108.1\|270169_271270_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|275336	TIGR04543, 2-ketoarginine_methyltransferase, 2-ketoarginine methyltransferase. This SAM-dependent C-methyltransferase performs the middle step of a three step conversion from arginine to beta-methylarginine. It performs a C-methylation at position 3 of 5-guanidino-2-oxopentanoic acid (keto-arginine). An aminotransferase converts arginine to 5-guanidino-2-oxopentanoic acid, and later converts 5-guanidino-3-methyl-2-oxopentanoic acid to beta-methylarginine.	2.47935e-13
NC_021174.1\|WP_096746675.1\|276934_278290_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.64282e-76
NC_021174.1\|WP_015603666.1\|274738_275248_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	1.76528e-48
NC_021174.1\|WP_015603895.1\|278397_279123_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.54439e-57
NC_021174.1\|WP_015603828.1\|279211_280543_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.59011e-132
NC_021174.1\|WP_015603150.1\|273527_274544_-\|1-aminocyclopropane-1-carboxylate-deaminase	gnl\|CDD\|183494	PRK12390, PRK12390, 1-aminocyclopropane-1-carboxylate deaminase; Provisional.	0
NC_021174.1\|WP_015602972.1\|280592_281501_+\|amidohydrolase-family-protein	gnl\|CDD\|226145	COG3618, COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	6.29855e-71
NC_021174.1\|WP_006027026.1\|268953_269250_-\|DUF1330-domain-containing-protein	gnl\|CDD\|377765	pfam07045, DUF1330, Domain of unknown function (DUF1330). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	3.01051e-35
NC_021174.1\|WP_015603742.1\|271946_272807_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	7.81861e-22
NC_021174.1\|WP_015603385.1\|283146_284703_+\|c-type-cytochrome	gnl\|CDD\|224771	COG1858, MauG, Cytochrome c peroxidase [Inorganic ion transport and metabolism].	8.28703e-84
NC_021174.1\|WP_006027011.1\|286323_287892_+\|tyrosinase-family-protein	gnl\|CDD\|365987	pfam00264, Tyrosinase, Common central domain of tyrosinase. This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.	5.36442e-30
NC_021174.1\|WP_015603364.1\|266341_267061_-\|alanyl-tRNA-editing-protein	gnl\|CDD\|225427	COG2872, COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only].	1.35764e-51
NC_021174.1\|WP_015604115.1\|287906_288680_+\|hypothetical-protein	gnl\|CDD\|378321	pfam09948, DUF2182, Predicted metal-binding integral membrane protein (DUF2182). This domain, found in various hypothetical bacterial membrane proteins having predicted metal-binding properties, has no known function.	3.07025e-16
NC_021174.1\|WP_015602484.1\|267396_268890_-\|FAD-binding-protein	gnl\|CDD\|178402	PLN02805, PLN02805, D-lactate dehydrogenase [cytochrome].	9.22118e-154

>NC_021174.1|WP_015603666.1|274738_275248_+|winged-helix-turn-helix-transcriptional-regulator
MYEIKKSTPKAAAQPAGADIDRVDRAILRVLQRDASISNVALAAKVNLSPPACLRRVERLKEMGLIRGIVALLEPKALNAGMLVMIGVVLDRSTPDSFDAFEQAAQKVSGCMECHVVTGEFDYVMLIRTRDSDTFNRLHAEQLLYLPGVRQIRTFVVLKEILSTTSFPI
>NC_021174.1|WP_015603150.1|273527_274544_-|1-aminocyclopropane-1-carboxylate-deaminase
MNLQKFPRYPLTFGPTPIQPLKRLSAHLGGKVELYAKRDDCNSGLAFGGNKTRKLEYLIPDALAQGCDTLVSIGGIQSNQTRQVAAVAAHLGLKCVLVQENWVNYHDAVYDRVGNIQMSRMMGADVRLVPDGFDIGFRKSWEDALADVRARGGKPYAIPAGCSDHPLGGLGFVGFAEEVRAQEAELGFTFDYVVVCSVTGSTQAGMVVGFAADGRADRVIGIDASAKPAQTREQILRIAKNTADRVELGRDVTSGDVVLDERFGGPEYGLPNEGTLEAIRLCAKLEGVLTDPVYEGKSMHGMIEKVRLGEFPAGSKVLYAHLGGVPALNAYSFLFRDG
>NC_021174.1|WP_015603240.1|273021_273495_-|hypothetical-protein
MNGALDLHREASAARWWQPPSSPTLVCVVGDDTLPAACCGALAKRLAGVPQIALLGCAEPARLHALWLDARSRARARLPADVAPLERALGALSRDAWLLLWSQQPQSLDWIGGVHGNRTLVVRHCPLTCDETELQRAADAALAALRAAVRLRIDAEY
>NC_021174.1|WP_015603742.1|271946_272807_+|AraC-family-transcriptional-regulator
MAKLDHRNQSRYWHSPGISGVDLLLADFTTHDYAPHVHDSLVIAVTEVGGSVFKSRGQTRLAEPDAVLVFNPCEPHSGRMGGSSRWRYRSFYLAEAGLSRVLTLLGMEQPRFFTSNVLNDPQLVEQFLTLHRAMDEQDDLLLQQELLVSSFGTLFSRHGLQAGLGFGAKADLPILKPALDLMNDSFDHALTLEQIAAAANLTSFQLITAFNRVIGLTPHAYLNQLRLRAALRELQAGRSLADAALTSGFYDQSALCNHFKRTFGMTPMQYTRALAPGKRAAAPIGI
>NC_021174.1|WP_155246037.1|271392_271959_+|hypothetical-protein
MTAGTAAALVQILSASQRIFVTQILGNWKKAAKLTSAFIIDRRPQFNWRSIFPRFDLSIRTGFVLYRENVFSWCIALHKKISRDDRYSPAARLPNLRKRKARSDIGCRFRIAVAIPSKISPSTRGARPAATGAAAHRGTELACRAMLTRADDIGRPAGARDAERRARSGTVRRRLFRFIGIGVRPWPS
>NC_021174.1|WP_075645108.1|270169_271270_-|methyltransferase-domain-containing-protein
MHLGKNGAFQFYPIQLNKVAIVLRRRLPHFKTRKGVAMQNVDRPTGSSLAGAAILLEIGSAYGVVDFIRHSKGFDVAALAERSGIDRPVIAEYVDAMREAGLLSLAKSGERDIYRPADDFPDVVNDVGYLSWALLACAPLIINAREFAADNALAQARHPRDGGLVARTSKWMGELSFYPQPERAILKLRPKKIVDLGSGSGGFLIRMLHQLDGARGVGVDLSATATEQAKQAAEANGFAGRLEFLHRPIQSLIDDPTPLKGADVVHAGFVMHDLLPAEERTLDALLETCREHASSGTVVIVDAVPLAPDQWERSFAAAFNHLHRNFMSRRLLSETEWREKFEKAGFGNVAVETLGHPGGRMILGSA
>NC_021174.1|WP_009915228.1|269310_270114_-|hypothetical-protein
MPITVDELVQKVKSHRCYTHPVFMNWAKVDPEPKVVGALFHQIQNFCASTRPGWNFPQALADHGLQKQSELMNEIVDSESGHGPELATMAGYIVNRAAGSAVIPDLYDQAAVEGVLKHYSDELLGSLPGYDDETGLTTQVRRAISVFERRKLVDVESTYRNLGTALALEMISNRQLIPGEKHCLVDSGLYDATLEVPEMHYLLEHWGEVGAEQQHEENARAAVKPALESEHAALVIEGAEEFLNALASVWDLLDASLLESGYVKKAA
>NC_021174.1|WP_006027026.1|268953_269250_-|DUF1330-domain-containing-protein
MTAYLLGRMAISDPSKYARYKALTPDIIARFGGRFLTRGGDKLTLEGPADERRIVLVEFADADAAARFYHSADYQHAKSLREGAADMQLMIVGGFEQK
>NC_021174.1|WP_015602484.1|267396_268890_-|FAD-binding-protein
MRDVTNDEQRSGGWGAFPVGAPPDGDAPAAFATPETVGRCVDELRTVVGERLVVGRAVREQHGKDISFHPGAPPDAVAFVQSTAEVAAITRVCHRLRVPLIPFGTGTSCEGHIAALRGGVCIDLSGMNRILRVSTEDLDCTVEAGVTRKQLNAHLHDTGLFFPIDPGADASIGGMCSTRASGTNAVRYGTMRESVLALEVVLPNGDVTSVGSRARKSAAGYDLARLFVGAEGTLGTITGVTLRLHPRPDQVSAAVCGFADLKAAVDSVIAIIQSGVPIARVELLDAMQIAACNRYSKLSLQERPTLFFEFAGFGAAVDEQIGWVGEICAGHGGSEFRWASRPEERSALWAARHDVWWATLALRPGCEGMPTDSCVPVSRLAEAVLAARADVDALGLVATICGHVGDGNFHVCIVIDPADADELARATELNRRLALRAIALGGTCTGEHGVGYGKIGYLEREHSTSLQLMAAVKRALDPRGIMNPGKVLHHDRYPPFD
>NC_021174.1|WP_015603364.1|266341_267061_-|alanyl-tRNA-editing-protein
MNRLFCQDDPDTLLLAGTVVDARPGAVRLSQHPFYPGGGGQLPDLGTVQWEGGVETVTGFSEDEGGLWIELANGVEIVGHVQSSVDAAFRRSMRELHTDLHVLNALVYRDFDGALVTGVQMNADRTARIDFDLPDADNDRLRALEAELNDVVHRDLPVRTRYVPLADAQQESGLLRSRSVAPPPTADGLVRIVEIDGLDSQACGGTHLASTGGSSPVRILKIENKGRSNRRVRLGLEPR
>NC_021174.1|WP_096746675.1|276934_278290_-|MFS-transporter
MPCTANQLIIYMNYRARRQQVDESSTRERAVMTKIARRLMPLLVIMFLIAFIDRQNVGFAKLQMVHALGMTETSYGLGASLFFIGYLLFEVPSTLALHRFGARLWLARIMMTWGVVTVLLGFTHSTSVFYVFRFLLGVAEAGFYPGVIYYLTLWFPQSHRTRVLGLFTLGSALANMLGSLAGGLLLSLDGRLGLAGWQWVFVATGLPAVAVALVALRLLPESVERATFLSDDEKRVALAALKREASPEAVSESPWRALVDPRVLMFALAYMLMSTSLYGVTYWLPTLLKSSGVPSSLNGLLNMIPWAIAALLLLWLPARLKRERIVLKAMAIVAGVGVAGFALSLALPGLPWRFAALVLGGACIPLLYPCFWSLPPRFFSGARAAASIAAINSIGNLGGFFAQNLMPYVGKVAGSASAPMLVPVVCLATLGVGMLAAASMAGRRRAAGMAA
>NC_021174.1|WP_015603895.1|278397_279123_+|GntR-family-transcriptional-regulator
MHATDDRLPRYQRLRDELAALIAARHWRPGEAIPTEQALAKRYDVAIGTVRKAVDLLVADGMLERFQGRGTFVRRASFDSSLFRFFRFQSKHGERRIPESRILRREVVEAPSAVAAALQIPARASVIAMTRVRLIDGAPMLAEEIWLPYDRFAAFARLELDSIGDLLYPVYEAHCNQIVASATETLTVEAIGPVHARLLRIEPGTPAVVIERLAYGYDRRPLEWRRSRGPASEFIYQAEIR
>NC_021174.1|WP_015603828.1|279211_280543_+|MFS-transporter
MFKWFAAVSPRERRTFWACFGGWALDALDVQMFSLVIPAIVAEWSLSRTQAGFVGGATLVASAVGGWAAGMLSDRFGRVRTLQWTIACFSVGTFACAFATSYPQFVVLKTLQGAGFGGEWAAGAVLMAETIRAEHRGKAMGAVQSAWALGWAAAVLLYALAFSLMPAELAWRAMFGIGLLPALLIVYVRRGIVEPSASASSASHASSTPGAPNEPAAARASAPLVGIFSRDMRRMTLIGALLGVGAHGGYYALMTWLPTYLKIERHLSVLGTGGYLAVIIVAFFCGCIASAQLLDRIGRRGTILAFAACCVATVIAYLLLPLGNAAMLVLGFPLGFFAAGIPASMGALFNELYPRGTRGTGVGFCYNFGRVASAGFPVLVGHMSAGMPLGTAIGIDAAIAYSIVVVAVLMLPETRGRALDDRANTHAADAGADRIGAPGAQHR
>NC_021174.1|WP_015602972.1|280592_281501_+|amidohydrolase-family-protein
MSDQEWNACAHAAAMRHTAGDITAIDAHAHVFETGLPLAGQRRYAPDYDAPLGAYLAQLDAHHVSHGVLVQPSFLGSDCRYLLRALAQQPRRLRGVAVIDAGCEPHVLDALDRAGIVGIRLNLIGMPDPALDGPAWRATLERIAALRWHVELHAQAHRLGRLIAPLLAHRLNIVVDHFGRPDPARGIADAGFRDLLRAAATRRVWVKISGVYRNWPLAPDEADTRAREAFDALAAEFGAERLVWGSDWPHTQFERTETFGRACALARRWMRDDAMRRAIFVETPARLFRFGESRGTQRVGSG
>NC_021174.1|WP_015603646.1|281674_283150_+|calcineurin-like-phosphoesterase
MPRPILRAAALVLTLAGAALFHACTSSIDNQPDAASAPANIQAAWVEIGDANQAIARVITNYTPPAATSGEPAPAVCPQLNADGKIARMTLRITAGTAAQRQTASDPADSKPSSFPVSVCETTLPANAQAVTVAGRALPLPKAKPQRVAIIADTGCRMKKADNAFQACSDATVWPFATIAASVAKLNPDLVLHVGDYHYRENACPPDIAGCKNSPWGYGWDTWRADLFEPAAPLLAKAPWVVVRGNHEECARAGQGWFRFLDPRPYSDARSCNDPANDGNANYSEPYAVPLGTGSQVIVFDTAKVGRAALKTTDVQFQIYQKQFQTVAALANKPGMSTTIFTNHHPILAFAPIPGSTPAPGNLALQSVMSSLYAQAYYPPGVQVALHGHVHDFQAINFASGHPATIVSGNGGDNLDVALPDPFPANLTPAPGVVIDKLSHNNSFGFLIMERRAAPARGWTFKAYTAAGKLLASCDQAGTTLTCDKTGFVAP
>NC_021174.1|WP_015603385.1|283146_284703_+|c-type-cytochrome
MTDSKRRIAARRAEAAAFAARACAIAFAPGQAAFGTMRKRRPIPTIAIIATIARAASGVLAACASAIAFASGPAAPGATAPARAKPAQDAVRAGTASPPPPTTILLPGAPPQRVVGTIGRGTPQVASKVDPTAAAFRPDPALVALGKRVFFDPALSEPRGTSCASCHDPGRAFAPTLSHAALAGPRVPQGSRPGHFSRRNAPSLLYVRYVPRRHFYQDDDALAPAPFGGLFSDGRADTLAEQLRGPLFDPDEMNNASPAALMRKIGGTALGAALAERFGASVRRDPERMARALGDAMQAYLQSDEMAPFSSRYDAYVTKRAPLTPQELRGLALFRNPDKGNCMSCHTLSDTASRPERSLFTDFGYDAIAVPRNRALPANRDPRHFDNGLCDTAAKLCWPEPTQWCGYLRTPGLRNVAVKESFMHNGVFDTLRDAVAFYNTRSTDPTRWYHGRDTFDDVPRAHRGNINVNSTPMNRRPGTPPAMTDADIDDLVAFLRTLTDARYVGLMPAAPDGKAARP
>NC_021174.1|WP_006027012.1|284873_285734_+|class-I-SAM-dependent-methyltransferase
MPNQSITAPDSTAVRVALWRALHVEIDAPPHVLDDVIGLELAAPDDDWRSRPDMEPQATRGYRASIVGRARFVEDLVDEQADGGVAQYVVLGAGLDTFAQRSAKRASHLRVFEIDQPGTQAWKRQRLIALGYGVPEWLRLVPVDFEASGAWRTQLSAAGFDDSRPAVVSSTGVSMYLTREAIADTLRQTATLAPGSTLAMTFLLPLELIDDPAERAQHAAVYERARAAGTPFVSFLSPPEMLALAREAGFREVRHVSTGDLVRRYFDGRPDGLRPSSGEAFLVAST
>NC_021174.1|WP_006027011.1|286323_287892_+|tyrosinase-family-protein
MLHANKKGEISMTYLRQNVWDLGADWAEPILWYARGVKAMQSRALDDRNSWRFYAAIHGFQQDLWRRVGYLNAHDKMPSTADIQAYWKQCQHGSWYFLPWHRGYLLALEAVVRDEVLKLRGPKNWALPYWNYFKPGQDLLPKAFASPDWPDGKGDNPLYVKQRYGPYNNGEVYVPTKWINMNALGDPDFEGVASGGSTGFGGVDTGFSHSGRVHGGIETQPHDAVHGIVGGRNRATGLPGLMSHPDIAGLDPIFWLHHANIDRLWEVWRRNPPTHVDPTAVNWLKGPAAIGERPFRMPMPHGENRTYTPGEMSDLSKLGYAYDDVSAPTKTPPTAARLTRLRARATAETPKEDFAVTDPRTVELFGASDQNLPVRGLEARSSVKLDADVHRKLTANLKATAAATSSTPDRVFLNLENVRGLDDATVLNVYVNVPEGEDPAKYPDHLAGCIALFGVSKATVAEDGHAGDGVTFVLEISHVIDALHLAGALPQSQLDVRLIAVTPVAEESKVSIGRISVYRQSA
>NC_021174.1|WP_015604115.1|287906_288680_+|hypothetical-protein
MKHAGRRLDAPLVALVSVSLIAWSALIVGAGGLTPPALCSIAGDWRVPLATWLRLAYLSNSPSKFASDSVMMVAAMMAPLAAAPLRHVLERSFARRRMRAALLFVAGYAAVWLVAWIGLQIVAIAFTWVMPGPVARTGAGLALALLWQASPAKQGFLNVCHRRPPLAAFGVAADRDALRFGLASGVSCAGNCWALMLLPLLAGHAHVPATIAVMCFIVAERLERPATPAWRCRGPGKAMRIAAAKVRAKLASLRLSV
>NC_021174.1|WP_015604122.1|289094_289367_+|hypothetical-protein
MEHLIRIVNDTDRQILAWLRSQVGDERVERAARHMGRVRKPYLSAVCRYLGVWPPISLRYPARRAEVDHTVGDRYLTLIRQHLATHAASR

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Crispr_ID: NC_021174_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021174_2

330926-330998

Orphan

Consensus_repeat	Method
AGCGCTTACTCTGGTCCCATGCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021174_2

>merge|NC_021174|2|330926-330998|CRISPRCasFinder
AGCGCTTACTCTGGTCCCATGCTTTGCAGTCGACCAGAGTTAGCGCTTTAGCGCTTACTCTGGTCCCATGCTT

>NC_021174|2|2|330926-330998|CRISPRCasFinder
AGCGCTTACTCTGGTCCCATGCTT	TGCAGTCGACCAGAGTTAGCGCTTT
AGCGCTTACTCTGGTCCCATGCTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021174.1\|WP_015603114.1\|331070_332315_-\|sarcosine-oxidase-subunit-beta-family-protein	unknown	unknown	gnl\|CDD\|273585
NC_021174.1\|WP_015603283.1\|337743_338751_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NC_021174.1\|WP_015603602.1\|321506_323657_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|226702
NC_021174.1\|WP_015603514.1\|326969_327605_-\|sarcosine-oxidase-gamma-subunit	unknown	unknown	gnl\|CDD\|226949
NC_021174.1\|WP_015603339.1\|339976_341458_+\|phage-tail-sheath-family-protein	unknown	unknown	gnl\|CDD\|226028
NC_021174.1\|WP_006028753.1\|321028_321481_-\|response-regulator	unknown	unknown	gnl\|CDD\|381108
NC_021174.1\|WP_006028757.1\|325710_325971_-\|hypothetical-protein	unknown	unknown	unknown
NC_021174.1\|WP_015603731.1\|326231_326465_+\|hypothetical-protein	unknown	unknown	unknown
NC_021174.1\|WP_015603081.1\|334006_335152_+\|GlxA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|227311
NC_021174.1\|WP_015603000.1\|326517_326970_-\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|224456
NC_021174.1\|WP_006028770.1\|339564_339954_+\|hypothetical-protein	unknown	unknown	unknown
NC_021174.1\|WP_015603238.1\|336313_337042_-\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|373097
NC_021174.1\|WP_015603598.1\|324666_325599_-\|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240633
NC_021174.1\|WP_015603113.1\|335427_336129_-\|DUF480-domain-containing-protein	unknown	unknown	gnl\|CDD\|377312
NC_021174.1\|WP_041861934.1\|335163_335349_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275253
NC_021174.1\|WP_006028755.1\|324141_324627_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|224678
NC_021174.1\|WP_075645202.1\|330599_330887_-\|sarcosine-oxidase-subunit-delta	unknown	unknown	gnl\|CDD\|377276
NC_021174.1\|WP_015603497.1\|339080_339350_+\|hypothetical-protein	unknown	unknown	unknown
NC_021174.1\|WP_015602562.1\|327594_330603_-\|sarcosine-oxidase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|273584
NC_021174.1\|WP_015603843.1\|332331_333717_-\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233

Protein	Function_ID	Function_description	E-value
NC_021174.1\|WP_015603114.1\|331070_332315_-\|sarcosine-oxidase-subunit-beta-family-protein	gnl\|CDD\|273585	TIGR01373, Sarcosine_oxidase_subunit_beta, sarcosine oxidase, beta subunit family, heterotetrameric form. This model describes the beta subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms. [Energy metabolism, Amino acids and amines].	0
NC_021174.1\|WP_015603283.1\|337743_338751_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.17147e-107
NC_021174.1\|WP_015603602.1\|321506_323657_-\|PAS-domain-S-box-protein	gnl\|CDD\|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	4.61919e-78
NC_021174.1\|WP_015603514.1\|326969_327605_-\|sarcosine-oxidase-gamma-subunit	gnl\|CDD\|226949	COG4583, COG4583, Sarcosine oxidase gamma subunit [Amino acid transport and metabolism].	1.26639e-57
NC_021174.1\|WP_015603339.1\|339976_341458_+\|phage-tail-sheath-family-protein	gnl\|CDD\|226028	COG3497, COG3497, Phage tail sheath protein FI [General function prediction only].	1.06661e-32
NC_021174.1\|WP_006028753.1\|321028_321481_-\|response-regulator	gnl\|CDD\|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.54691e-72
NC_021174.1\|WP_015603081.1\|334006_335152_+\|GlxA-family-transcriptional-regulator	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	3.71407e-121
NC_021174.1\|WP_015603000.1\|326517_326970_-\|dihydroneopterin-aldolase	gnl\|CDD\|224456	COG1539, FolB, Dihydroneopterin aldolase [Coenzyme metabolism].	3.16997e-28
NC_021174.1\|WP_015603238.1\|336313_337042_-\|glutathione-S-transferase	gnl\|CDD\|373097	pfam14497, GST_C_3, Glutathione S-transferase, C-terminal domain. This domain is closely related to pfam00043.	8.9597e-32
NC_021174.1\|WP_015603598.1\|324666_325599_-\|2-hydroxyacid-dehydrogenase	gnl\|CDD\|240633	cd12156, HPPR, Hydroxy(phenyl)pyruvate Reductase, D-isomer-specific 2-hydroxyacid-related dehydrogenase. Hydroxy(phenyl)pyruvate reductase (HPPR) catalyzes the NADP-dependent reduction of hydroxyphenylpyruvates, hydroxypyruvate, or pyruvate to its respective lactate. HPPR acts as a dimer and is related to D-isomer-specific 2-hydroxyacid dehydrogenases, a superfamily that includes groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	7.01387e-133
NC_021174.1\|WP_015603113.1\|335427_336129_-\|DUF480-domain-containing-protein	gnl\|CDD\|377312	pfam04337, DUF480, Protein of unknown function, DUF480. This family consists of several proteins of uncharacterized function.	1.90225e-81
NC_021174.1\|WP_041861934.1\|335163_335349_-\|hypothetical-protein	gnl\|CDD\|275253	TIGR04460, endura_MppR, enduracididine biosynthesis enzyme MppR. Members of this family are MppR, one of three enzymes involved in synthesizing enduracididine, a non-proteinogenic amino acid used in non-ribosomal peptide synthases to make natural products such as enduracidin from Streptomyces fungicidicus ATCC 21013. MppR is belongs to the acetoacetate decarboxylase-like superfamily. MppR catalyzes an aldol condensation and a dehydration, not a decarboxylation.	0.000933382
NC_021174.1\|WP_006028755.1\|324141_324627_-\|peroxiredoxin	gnl\|CDD\|224678	COG1764, osmC, Organic hydroperoxide reductase [Secondary metabolites biosynthesis, transport and catabolism].	7.3264e-19
NC_021174.1\|WP_075645202.1\|330599_330887_-\|sarcosine-oxidase-subunit-delta	gnl\|CDD\|377276	pfam04267, SoxD, Sarcosine oxidase, delta subunit family. Sarcosine oxidase is a hetero-tetrameric enzyme that contains both covalently bound FMN and non-covalently bound FAD and NAD(+). This enzyme catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, and 5,10-CH2-tetrahydrofolate (H4folate) in a reaction requiring H4folate and O2.	1.06748e-47
NC_021174.1\|WP_015602562.1\|327594_330603_-\|sarcosine-oxidase-subunit-alpha-family-protein	gnl\|CDD\|273584	TIGR01372, sarcosine_oxidase_alpha_subunit, sarcosine oxidase, alpha subunit family, heterotetrameric form. This model describes the alpha subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason.Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines].	0
NC_021174.1\|WP_015603843.1\|332331_333717_-\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0

>NC_021174.1|WP_075645202.1|330599_330887_-|sarcosine-oxidase-subunit-delta
MLIECPWCGPRAESEFSCGGEADIARPLDTDTLSDREWGDYVFMRRNPRGAHREQWLHTQGCRRWFVAQRDTVTYEFQGYETFGAAADAAKDTSK
>NC_021174.1|WP_015602562.1|327594_330603_-|sarcosine-oxidase-subunit-alpha-family-protein
MSQKDRLGAGGRINRAQPLTFTFNGRTYQGFQGDTLASALLANGVHFVARSFKYHRPRGIVTAGVDEPNAVVQLETGAHTVPNARATEIELYQGLVATSVNAKPSLEHDRMAVMQKFARFLPAGFYYKTFMWPRNLWPKYEEKIREAAGLGKAPDTLDADRYDKCYAHCDVLVVGGGPTGLAAAHAAAANGARVILVDDQRELGGSLLAARAEIDGKPALQWVEKIEAALAKLPDVKILTRSTAFGYQDHNLVTVVQRLTDHLPVSMRKGTREMIWKVRAKRVILAAGAHERPLVFGNNDLPGVMTASAVSTYIHRYGVLPGRVAVVATNNDRGYQCALDLKACGAKVTVVDARASTRGALPAVAKRNGITVMSGAVVSSAAGGLRVASVDVASYASGKSGGRIATLPCDLVAMSGGFSPVLHLFAQSGGKAHWNDDKACFVPGKPVQAEASVGAAAGEFELSRALRLAVDAGVAAAKSTGFAAERPPVPKVAEAVEDALLPLWLASGAAAAVRGPKQFVDFQNDVGAADILLAAREGFESVEHVKRYTAMGFGTDQGKLGNINGMAILAQALGKTIPETGTTTFRPNYTPVSFGAFAGRELGDFLDPVRKTCVHEWHVEHGAMFEDVGNWKRPWYFPKRGEDLHAAVKRECLAVRNGVGILDASTLGKIDIQGPDAVRLLNWVYTNPWNKLEVGKCRYGLMLDENGMVFDDGVTVRLGEQHFMMTTTTGGAARVLTWLERWLQTEWPDMSVRLASVTDHWATFAVVGPKSRKVVQKVCKDIDFANDAFPFMSYRDGTVAGVKSRVMRISFSGELAYEVNVPANAGRAVWEALMEAGAEFDITPYGTETMHVLRAEKGYIIVGQDTDGSITPFDLGMGGLVAKSKDFLGRRSLARADTAKSGRKQFVGLLTDDAQYVLPEGGQIVEVDAAARADGTTPMLGHVTSSYYSPILKRSIALAVVKGGLSRMGERVAVSLANGRRVAATISSPVFYDTEGVRQHVE
>NC_021174.1|WP_015603514.1|326969_327605_-|sarcosine-oxidase-gamma-subunit
MWNETRNEASVAVHAQGGARLESPLVGAGDALKAYDARGSKAFRFRERPFLDLVNVRGEPNDSAFVRAFEQVVGCRPPVKPNTVARGADHDVLWLGPDEWLVRSNGAVAAGALEAKLAQAVQGLHAAAVDVGSGYTVVEASGARARDVLARGCPLDLHPRVFGVGQCAQSHYFKASITLVPMGDEAFDIVVRRSFADYFCRIMLDAATPLA
>NC_021174.1|WP_015603000.1|326517_326970_-|dihydroneopterin-aldolase
MKPAEGPFAALDPARGRGWSVFVDALKVPARIGIHPHEHAAPQPVVIDARLAYRREPSEAGGDGWIDYDAYCARLASFLARKPHTRLLETLALEIAVLSFDEWPALDALTLALHKPKIRPGTKRVGVELDWTRADHAAWRAAAREAAARG
>NC_021174.1|WP_015603731.1|326231_326465_+|hypothetical-protein
MKTTAILSALAAGLCFSISSFAQAPASAPGQVWVNTDTKVYHCAADKRYGKTQHGEYMPEAAAKAQGFRASHGKACS
>NC_021174.1|WP_006028757.1|325710_325971_-|hypothetical-protein
MFASFEPTHTGFVAEIDGCRCSIEGAPSPIADRIDWRWTIAQPEPDNLDGSDPYRYEVLATGETVTPLQAEQQIVAWLEAHPPEDA
>NC_021174.1|WP_015603598.1|324666_325599_-|2-hydroxyacid-dehydrogenase
MKPQLLVLIPLRDRAHAQVADAFDVLHAPTPDQRRAAIAERGAAVRAVLTNGTVGLFADEIARLPKLEFIAALGVGYENIALDDARSRGVVVVNGAGTNDDCVADHAFALLLAAVRGVPKLDAACRAGVWRDALPMPPNVSGKRLGIVGLGNIGEKIARRAAGFDLDIGYHNRRPREGAAYRYFAELHALARWADFLVVATPGGAATRHLIDARILDALGERGFLVNVSRGSVVDTAALADALRAGRVAGAGLDVYEGEPQPPRALVALDNVVLTPHLGGWSPEALERSVRQFLENAARHFAGQPVLTPI
>NC_021174.1|WP_006028755.1|324141_324627_-|peroxiredoxin
MSTYTAEVAWQKQEGETFADNRYSRKHEWRFDGGVRVPASSSPHVVRVPFSDPAAVDPEEAFVAALSSCHMLWFLSLAAQKKLVVTGYRDVAEGTMAKNAQGQEVMTRVVLKPHVTFGGERAPTRDEVDALHHAAHDACYLANSVKSDIDIEGSWAHEPAR
>NC_021174.1|WP_015603602.1|321506_323657_-|PAS-domain-S-box-protein
MTSGIRRLGKKASRWIDFGLWTAAVLLLLTAGIGALGTARLFDSEADVHRASEVISGLERLLSLARDMETGQRGYILTGKPDYLQPYEAALPEVRKQFDALAPLVQDDAVQQRRLATLRTLLEKKQKELAVTIELRKTEGFDAAEAIVSSDAGKIFMDLARAMVNEMETTVQQQLSVLRDRARATRDIAIGVGLASGLLTLVVCVSFGYVMRRLLLVEAAAAHDLFEQRELLHVTLASIGDGVIATDVGGRITFFNRVAEQMTSLAAAAAVGQPIEQVLTFRHAATQRVIDNPARVAVERKRTATLPVHSRFVDRGGRELPVDGNAAPTFDAKGKLVGAVLVVRDVSERERAEERFRLAVEAAPNAMIMVGRDGRIVLVNSQAEKLFGYARGDMIGHGIDMLVPERFRAGHSAYRGAFFGKPDARPMGEGRDLFGLRRDGGEFPVEIGLNPITTSEGAFVLCSIADITARKRAELELRRRSEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARADEFIGHAVDGATRMQSLIDDLLSYSRVGRLEDARQPVDGERALDEALRNLSAAIRESGAQITHDRLPVVHGIAAQLVLLLQNLIGNAIKFRSKDRVAQIHLEADVRDDAWVFRVRDNGIGIDPQYFERIFLIFQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGRGTTFSFTLSRPGADETH
>NC_021174.1|WP_006028753.1|321028_321481_-|response-regulator
MIADERGNFVEILLVEDSPTDVMMTREALEYYKVLNPLRVVEDGVAAMAYLRREGPYASARRPGLIILDLNLPKKSGREVLQELKLDPDLSTIPVVILTTSKSDEDVARSYGLHANCYITKPVDFAKFTHVVHSINEFWLGVVTLPPVKP
>NC_021174.1|WP_015603114.1|331070_332315_-|sarcosine-oxidase-subunit-beta-family-protein
MSRYSIFSLFRNGLSYHENWERQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNVAVLEKGWIGGGNTARNTTIVRSNYLWDESAALYEKAMKLWEGLAQDLNYNVMFSQRGVMNLAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKELEPTINLNSRYPVLGASIQRRGGVARHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTTTLADMAGVRLPLESHPLQALVSEPIKPVVNTVVMSNAVHAYISQSDKGDLVIGAGIDQYTGFGQRGSFQIIEGTLQAIIEMFPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNCGWGTGGFKATPGSGWVFAHTIARDAPHELNAPFALERFYTGHLIDEHGAAAVAH
>NC_021174.1|WP_015603843.1|332331_333717_-|L-serine-ammonia-lyase
MNVSVFDLFKIGIGPSSSHTVGPMIAARRFASHVEDANLLGFVRRVRAELYGSLGATGKGHGTDKAVLLGLEGHLPDLIDPDLIEPRLKAIRAEKSLALLGKRSIRFDEKDDIGFYRKLMSGTGVVHPNGMRFQAFDEHGQLLVEKEYYSVGGGFVVNRDGDRVNGARAATDVPYPFRTGDDLMRACRASGLSIAELTLRNECALRPADEVRAGLVAIWKTMAACVERGCKVDGELPGPMRVKRRAAELHTRLRSRSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSNEAGIADFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAALAAVMGGTPGQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRIALKGDGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC
>NC_021174.1|WP_015603081.1|334006_335152_+|GlxA-family-transcriptional-regulator
MTADVPASPLAADSAQPRLRFGIVLLPNFTLTAFSGFVDMLRLSADDGDHSKPVRCSWTVIGDTLAPVRASCGIQLTPWQTFDAADAFDYVVVVGGLLHSGPQAGPQTLEFIRRAAAAGANLVGICTGAFALMRAGVLDGHRICVSWFHYWDFIERFPNADPDLLIADRLFVIDRRRITCSGGRASIDVAAAILLRHFDHATVQKALRILLVGEMQKGNAPQPHPPGLEPATHPKVKRAILLMEQHVGRALPLDELACKLDLSTRQLERLFKAQTGKSPQAFAKQVRLRTAAWLLTSSDRTVADIASSCGFADASHLGREFRKQFGAPPAAYREKGGAAGGADAAIARTADDAQMDWGADSGADSEEDADAGASGSGIDAG
>NC_021174.1|WP_041861934.1|335163_335349_-|hypothetical-protein
MPDGLAPASGERAGRCALYFCDWQFATTDGLEYLDPVGSQYKETLLLVAPASRRSSAGTSR
>NC_021174.1|WP_015603113.1|335427_336129_-|DUF480-domain-containing-protein
MNSTPDAFQRPPLRALTPLEARVLGVLIEKQHTVPDTYPLSLNALTAGCNQKTARSPVMNVSEAEVLTAIDGLKRLSLASEGSSSRVPRFEHNMNRVLGIPSQAAALLTMLLLRGSQTAAELRLNSARLHGFADISSVEAFLDELAARTPPLVVKLSRAPGERESRWLHLLCGDVAPEAPARGAHDDAVPPSEFEALKAEQKALTAELAQLRAFVEYMANELGIDIGKFTRES
>NC_021174.1|WP_015603238.1|336313_337042_-|glutathione-S-transferase
MRYELYYWPDIQGRGEFVRLALEAAEAEYVDIARESSRKGMGVPAMMRLLESDSAECLPFAPPFLKAGDQIIGQTANILLFLGARHDLAPRDDAGRLWAHQLQLTVSDFVVEIHDTHHPIASGLYYEDQKAQAAMRAEDFIEHRLPKFLDYFGRVLAHNPHKHGYMVGARLTYVDLSMFQLIEGLRYAFPKAFSHVEKRHAALIELHDRVAQHPPVARYLASERRIPFNEQGIFRHYAELDR
>NC_021174.1|WP_015603283.1|337743_338751_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MNDFVRLNLIGQSPRFLAALDLIRKYARSAAAVLIQGETGTGKELAARALHYLSDRRDLPFVPVNSGAIPEHLIESELFGHVRGAFTDARETRHGLITEARGGTLFLDEVEALSARAQVALLRFLQDREYRPVGGTLLRSSDARVIAATNLDLAVLARKGLFRSDLLYRLDVLPLHLPPLRERSGDVALLADTFVERLNGLGKGPAKALLPGSRAALNRHTWPGNVRELENLIQREYVLAGDACCIDLTTAGDGHAPAASIACATPADESYKAAKARAVAEFERSYIVALLSRSGGNLSLASRLSGKDRSDIGKLLRKHGIERQRFTAAGQPNRD
>NC_021174.1|WP_015603497.1|339080_339350_+|hypothetical-protein
MNTTQDDDARRGIAQAITRYLANHPNAADTVDGIAAYWLTEIEESAAMFRIDHIQRALDQLVRQGVLTTCMLPGGHVLYRKPPVPQERA
>NC_021174.1|WP_006028770.1|339564_339954_+|hypothetical-protein
MANLNWSLSLQVTGGPTINAGQDGLSVEGVDTIDVTIDAGDADKVVQIQPGAAGHVHVLAVKSDLYNSKLSFKASDGATDSAKVVLDAPQLYAGGATALFGIDPKQLKLSNAGAAAAHVTIFVARDAKV
>NC_021174.1|WP_015603339.1|339976_341458_+|phage-tail-sheath-family-protein
MPSPLTYPGVYIEEVPSGVRSITGVATSIALFIGWAARGRNDRAVRISSFADYQRTFGGLDRRTLLGHAVMQFFDNGGSDAYIVRLAGAGALASTAAIGDLTFHASSPGKWGDGYAVRTTRRQPPDDAHFTVDVLDKQNGNAIVESFQNVSMDKGDTRFVEGVINDRSGYIAVSAASGTTPADATAPLGGGDDGTLLQPGTAGFHAALAAVFGVGSITDRIDLFNLVCVPGETDAGALAALQTACRKRRAFLIADADSMATVALLGAGVSTTLTGSDALNSALFFPWVRAADPLQQGAIASFPPCGFVAGVFARTDGARGVWKAPAGSDASLNGASGLAIAMSDAENGQLNPLGINCLRTLPVYGNVVWGARTLHGQNDRGSEWKYVPVRRMALFLEESLYRGTQWVVFEPNDEPLWAQIRLNVGAFLQDLFRQGAFQGRTPRDAYFVKCDGETTTQADINLGVVNILVGFAPLKPAEFVVLQLQQIAGDIPT

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NC_021173.1	856126-856150	2	0.92

1. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to position: 856126-856150, mismatch: 2, identity: 0.92

tgcagtcgaccagagttagcgcttt	CRISPR spacer
tgcggtcgaccagagtgagcgcttt	Protospacer
***.************ ********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	865576-865600	3	0.88
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	870256-870280	3	0.88
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	445496-445520	3	0.88
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	445545-445569	3	0.88
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	220705-220729	3	0.88
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	1412239-1412263	5	0.8
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	1416907-1416931	5	0.8
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	445594-445618	5	0.8
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NZ_CP049157	Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence	601858-601882	5	0.8
NC_021174_2	2.1\|330950\|25\|NC_021174\|CRISPRCasFinder	330950-330974	25	NZ_CP049317	Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence	1040813-1040837	5	0.8

1. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 3, identity: 0.88

tgca-gtcgaccagagttagcgcttt	CRISPR spacer
-gcgtgtcgaccagagttagcgctta	Protospacer
 **. ********************

2. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 3, identity: 0.88

tgca-gtcgaccagagttagcgcttt	CRISPR spacer
-gcgtgtcgaccagagttagcgctta	Protospacer
 **. ********************

3. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.88

tgcagtcgaccagagttagcgcttt	CRISPR spacer
ggctgtcgacgagagttagcgcttt	Protospacer
 ** ****** **************

4. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.88

tgcagtcgaccagagttagcgcttt	CRISPR spacer
ggctgtcgacgagagttagcgcttt	Protospacer
 ** ****** **************

5. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 3, identity: 0.88

tgcagtcgaccagagttagcgcttt	CRISPR spacer
tcctgtcgatcagagttagcgcttt	Protospacer
* * *****.***************

6. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 5, identity: 0.8

tgcagtcgaccagagttagcgcttt	CRISPR spacer
ccatgtcgaccagagttggcgcttt	Protospacer
.   *************.*******

7. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 5, identity: 0.8

tgcagtcgaccagagttagcgcttt	CRISPR spacer
ccatgtcgaccagagttggcgcttt	Protospacer
.   *************.*******

8. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.8

tgcagtcgaccagagttagcgcttt	CRISPR spacer
ctgtgtcgacgagagttagcgcttt	Protospacer
.   ****** **************

9. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to NZ_CP049157 (Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence) position: , mismatch: 5, identity: 0.8

tgcagtcgaccagagttagcgcttt	CRISPR spacer
ctgtgtcgaccagagttggcgcttt	Protospacer
.   *************.*******

10. spacer 2.1|330950|25|NC_021174|CRISPRCasFinder matches to NZ_CP049317 (Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence) position: , mismatch: 5, identity: 0.8

tgcagtcgaccagagttagcgcttt	CRISPR spacer
ctgtgtcgaccagagttggcgcttt	Protospacer
.   *************.*******

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

311888 : 378156

Escherichia_phage(30.0%)

holin,tail,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006028749.1\|311888_313586_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	1.3e-50	29.3
WP_015603035.1\|314505_317877_+	hypothetical protein	NA	NA	NA	NA
WP_015603567.1\|318062_319490_+	MFS transporter	NA	NA	NA	NA
WP_015603436.1\|319553_321032_-	PAS domain-containing protein	NA	NA	NA	NA
WP_006028753.1\|321028_321481_-	response regulator	NA	NA	NA	NA
WP_015603602.1\|321506_323657_-	PAS domain S-box protein	A0A1V0SGX0	Hokovirus	1.7e-18	26.1
WP_006028755.1\|324141_324627_-	peroxiredoxin	NA	NA	NA	NA
WP_015603598.1\|324666_325599_-	2-hydroxyacid dehydrogenase	A0A285PXZ1	Cedratvirus	1.7e-20	33.6
WP_006028757.1\|325710_325971_-	hypothetical protein	NA	NA	NA	NA
WP_015603731.1\|326231_326465_+	hypothetical protein	NA	NA	NA	NA
WP_015603000.1\|326517_326970_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_015603514.1\|326969_327605_-	sarcosine oxidase gamma subunit	NA	NA	NA	NA
WP_015602562.1\|327594_330603_-	sarcosine oxidase subunit alpha family protein	NA	NA	NA	NA
WP_075645202.1\|330599_330887_-	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_015603114.1\|331070_332315_-	sarcosine oxidase subunit beta family protein	NA	NA	NA	NA
WP_015603843.1\|332331_333717_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_015603081.1\|334006_335152_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_041861934.1\|335163_335349_-	hypothetical protein	NA	NA	NA	NA
WP_015603113.1\|335427_336129_-	DUF480 domain-containing protein	NA	NA	NA	NA
WP_015603238.1\|336313_337042_-	glutathione S-transferase	NA	NA	NA	NA
WP_015603283.1\|337743_338751_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_015603497.1\|339080_339350_+	hypothetical protein	NA	NA	NA	NA
WP_006028770.1\|339564_339954_+	hypothetical protein	NA	NA	NA	NA
WP_015603339.1\|339976_341458_+\|tail	phage tail sheath family protein	A0A1J0GW47	Streptomyces_phage	2.6e-34	30.4
WP_006028772.1\|341491_342016_+\|tail	phage tail protein	NA	NA	NA	NA
WP_075645060.1\|342074_342803_+	hypothetical protein	NA	NA	NA	NA
WP_041861935.1\|342799_343636_+	hypothetical protein	NA	NA	NA	NA
WP_015603125.1\|343632_344982_+	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_015602575.1\|344978_346907_+	ATP-binding protein	A0A2D2W2C3	Stenotrophomonas_phage	8.2e-09	34.3
WP_015603041.1\|346903_347350_+	hypothetical protein	NA	NA	NA	NA
WP_015603571.1\|347346_348612_+	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_015603071.1\|348608_348782_+	hypothetical protein	NA	NA	NA	NA
WP_015603540.1\|348778_351574_+	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_006028782.1\|351570_352230_+	hypothetical protein	NA	NA	NA	NA
WP_006028783.1\|352363_352714_+	hypothetical protein	NA	NA	NA	NA
WP_015603911.1\|352727_353852_+	hypothetical protein	NA	NA	NA	NA
WP_006028785.1\|353848_354361_+	hypothetical protein	NA	NA	NA	NA
WP_015602894.1\|354363_354681_+	hypothetical protein	NA	NA	NA	NA
WP_006028787.1\|354691_355060_+	GPW/gp25 family protein	NA	NA	NA	NA
WP_102812148.1\|355092_357591_+\|plate	putative baseplate assembly protein	A0A1Q1PVP2	Phage_DP-2017a	1.6e-09	21.4
WP_041862105.1\|357713_360329_+\|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_015602716.1\|360325_362368_+	hypothetical protein	NA	NA	NA	NA
WP_102812147.1\|362402_365642_+	hypothetical protein	NA	NA	NA	NA
WP_015602957.1\|365663_366212_+	hypothetical protein	NA	NA	NA	NA
WP_006028793.1\|366325_366793_-	cupin domain-containing protein	NA	NA	NA	NA
WP_015602755.1\|366852_367467_-	HAD family phosphatase	NA	NA	NA	NA
WP_015603993.1\|367657_368362_+	FadR family transcriptional regulator	NA	NA	NA	NA
WP_015603177.1\|368433_369324_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	1.9e-77	57.3
WP_015603703.1\|369343_370687_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	8.1e-88	45.6
WP_015603522.1\|370683_371325_+	aldolase	A0A077SK32	Escherichia_phage	3.3e-39	45.1
WP_009915291.1\|371426_372749_+	MFS transporter	NA	NA	NA	NA
WP_015603788.1\|372810_373587_+	hydroxypyruvate isomerase family protein	NA	NA	NA	NA
WP_006028801.1\|373614_374586_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_015603926.1\|375053_375746_+	aspartyl/asparaginyl beta-hydroxylase domain-containing protein	S4VR59	Pandoravirus	2.0e-21	36.8
WP_015603322.1\|375938_376913_+	hypothetical protein	NA	NA	NA	NA
WP_015603265.1\|376963_377131_-	aspartyl/asparaginyl beta-hydroxylase	NA	NA	NA	NA
WP_009915293.1\|377205_378156_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_021173

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_021173_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021173_1

2516004-2516197

Orphan

Consensus_repeat	Method
CGCAACCTCGAGCACCCCGCTCGCGCCGCTCACGAACATCGTGTCGACGGT	PILER-CR

2 spacers

The CRISPR arrays of NC_021173_1

>merge|NC_021173|1|2516004-2516197|PILER-CR
CCGCTCGCGCCGATCACGGCCGCCGTCGGCGGCCTGACGGGCACGCTGAGCGGCGTCGGCGGCGCAACCTCGGGCACCCCGCTCGCGCCGCTCACGAACGTCGTGTCGACGGTCACGGGTGCGCTCTCGGGCGCCGCGGGCAGCGCAGGCTCGAGCTCGCCGCTCGCGCCGCTCACGAACATCGTGTCGACGGT

>NC_021173|1|1|2516004-2516197|PILER-CR
CCGCTCGCGCCGATCACGGCCGCCGTCGGCGGCCTGACGGGCACGCTGAGC	GGCGTCGGCGGCGCAACCTCGGGCACCCCGCTCGCGCCGCTCAC
GAACGTCGTGTCGACGGTCACGGGTGCGCTCTCGGGCGCCGCGGGCAGCGC	AGGCTCGAGCTCGCCGCTCGCGCCGCTCAC
GAACATCGTGTCGACGGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021173.1\|WP_015601426.1\|2523841_2525119_-\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	unknown	unknown	gnl\|CDD\|235571
NC_021173.1\|WP_075644846.1\|2520903_2521110_-\|hypothetical-protein	unknown	unknown	unknown
NC_021173.1\|WP_015600665.1\|2507018_2508014_-\|type-II-secretion-system-(T2SS),-F-family-protein	unknown	unknown	gnl\|CDD\|227300
NC_021173.1\|WP_006026552.1\|2513043_2513511_-\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|377921
NC_021173.1\|WP_015602187.1\|2518004_2519684_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NC_021173.1\|WP_006026554.1\|2510655_2511981_-\|type-II-and-III-secretion-system-protein-family-protein	unknown	unknown	gnl\|CDD\|227299
NC_021173.1\|WP_015602058.1\|2516592_2517855_+\|collagen-like-triple-helix-repeat-containing-protein	unknown	unknown	gnl\|CDD\|374271
NC_021173.1\|WP_041861706.1\|2513507_2514014_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227295
NC_021173.1\|WP_009912631.1\|2519912_2520374_+\|DUF2147-domain-containing-protein	unknown	unknown	gnl\|CDD\|378304
NC_021173.1\|WP_006026544.1\|2521106_2522204_-\|cell-division-protein-ZapE	unknown	unknown	gnl\|CDD\|224402
NC_021173.1\|WP_006026545.1\|2520521_2520932_-\|transposase	unknown	unknown	gnl\|CDD\|379129
NC_021173.1\|WP_015601780.1\|2522311_2523742_-\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|235779
NC_021173.1\|WP_015600113.1\|2514095_2514266_-\|Flp-family-type-IVb-pilin	unknown	unknown	gnl\|CDD\|226366
NC_021173.1\|WP_015602285.1\|2512044_2512956_-\|Flp-pilus-assembly-protein-CpaB	unknown	unknown	gnl\|CDD\|274472
NC_021173.1\|WP_015601278.1\|2509350_2510589_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|349765
NC_021173.1\|WP_009912629.1\|2519793_2519925_+\|hypothetical-protein	unknown	unknown	unknown
NC_021173.1\|WP_015601625.1\|2525256_2528121_-\|2-oxoglutarate-dehydrogenase-E1-component	unknown	unknown	gnl\|CDD\|236499
NC_021173.1\|WP_015600771.1\|2505993_2507013_-\|type-II-secretion-system-F-family-protein	unknown	unknown	gnl\|CDD\|224975
NC_021173.1\|WP_015600967.1\|2508006_2509347_-\|CpaF-family-protein	unknown	unknown	gnl\|CDD\|227297
NC_021173.1\|WP_041861705.1\|2505042_2505957_-\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|227343

Protein	Function_ID	Function_description	E-value
NC_021173.1\|WP_015601426.1\|2523841_2525119_-\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	gnl\|CDD\|235571	PRK05704, PRK05704, 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase.	0
NC_021173.1\|WP_015600665.1\|2507018_2508014_-\|type-II-secretion-system-(T2SS),-F-family-protein	gnl\|CDD\|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	4.46803e-43
NC_021173.1\|WP_006026552.1\|2513043_2513511_-\|pilus-assembly-protein	gnl\|CDD\|377921	pfam07811, TadE, TadE-like protein. The members of this family are similar to a region of the protein product of the bacterial tadE locus. In various bacterial species, the tad locus is closely linked to flp-like genes, which encode proteins required for the production of pili involved in adherence to surfaces. It is thought that the tad loci encode proteins that act to assemble or export an Flp pilus in various bacteria. All tad loci but TadA have putative transmembrane regions, and in fact the region in question is this family has a high proportion of hydrophobic amino acid residues.	2.06223e-10
NC_021173.1\|WP_015602187.1\|2518004_2519684_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	2.75647e-65
NC_021173.1\|WP_006026554.1\|2510655_2511981_-\|type-II-and-III-secretion-system-protein-family-protein	gnl\|CDD\|227299	COG4964, CpaC, Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion].	2.42088e-96
NC_021173.1\|WP_015602058.1\|2516592_2517855_+\|collagen-like-triple-helix-repeat-containing-protein	gnl\|CDD\|374271	pfam15984, Collagen_mid, Bacterial collagen, middle region. Collagen_mid is the conserved central region of bacterial collagen triple helix repeat proteins.	1.38227e-36
NC_021173.1\|WP_041861706.1\|2513507_2514014_-\|hypothetical-protein	gnl\|CDD\|227295	COG4960, CpaA, Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	1.86908e-13
NC_021173.1\|WP_009912631.1\|2519912_2520374_+\|DUF2147-domain-containing-protein	gnl\|CDD\|378304	pfam09917, DUF2147, Uncharacterized protein conserved in bacteria (DUF2147). This domain, found in various hypothetical prokaryotic proteins, has no known function.	2.74309e-37
NC_021173.1\|WP_006026544.1\|2521106_2522204_-\|cell-division-protein-ZapE	gnl\|CDD\|224402	COG1485, COG1485, Predicted ATPase [General function prediction only].	3.91487e-177
NC_021173.1\|WP_006026545.1\|2520521_2520932_-\|transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.6999e-25
NC_021173.1\|WP_015601780.1\|2522311_2523742_-\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|235779	PRK06327, PRK06327, dihydrolipoamide dehydrogenase; Validated.	0
NC_021173.1\|WP_015600113.1\|2514095_2514266_-\|Flp-family-type-IVb-pilin	gnl\|CDD\|226366	COG3847, Flp, Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion].	2.22661e-12
NC_021173.1\|WP_015602285.1\|2512044_2512956_-\|Flp-pilus-assembly-protein-CpaB	gnl\|CDD\|274472	TIGR03177, pilus_cpaB, Flp pilus assembly protein CpaB. Members of this protein family are the CpaB protein of Flp-type pilus assembly. Similar proteins include the FlgA protein of bacterial flagellum biosynthesis.	1.09932e-52
NC_021173.1\|WP_015601278.1\|2509350_2510589_-\|transcriptional-regulator	gnl\|CDD\|349765	cd03111, CpaE-like, pilus assembly ATPase CpaE. This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains 7 genes: pilA, cpaA, cpaB, cpaC, cpaD, cpaE and cpaF. These genes are clustered together on chromosome.	1.33361e-73
NC_021173.1\|WP_015601625.1\|2525256_2528121_-\|2-oxoglutarate-dehydrogenase-E1-component	gnl\|CDD\|236499	PRK09404, sucA, 2-oxoglutarate dehydrogenase E1 component; Reviewed.	0
NC_021173.1\|WP_015600771.1\|2505993_2507013_-\|type-II-secretion-system-F-family-protein	gnl\|CDD\|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	3.3028e-15
NC_021173.1\|WP_015600967.1\|2508006_2509347_-\|CpaF-family-protein	gnl\|CDD\|227297	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion].	2.90799e-158
NC_021173.1\|WP_041861705.1\|2505042_2505957_-\|pilus-assembly-protein	gnl\|CDD\|227343	COG5010, TadD, Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking and secretion].	2.98142e-13

>NC_021173.1|WP_015600113.1|2514095_2514266_-|Flp-family-type-IVb-pilin
MKQLMHRFFKEEAGVTAIEYGLIAGLIAVAIATTVGTVGTDLSSLFSTIASKLPAA
>NC_021173.1|WP_041861706.1|2513507_2514014_-|hypothetical-protein
MIRLFSIGFFFAWAAAVAIADCRNRRIPNELVFAGFAAVIIFTFCRQNPFETTLTGALVGATVGLVSLFPFFALRVMGAADVKVFAVLGAWCGLPALPRLWIVASVAAGIHALGLMLVTRTPLGSLGRNGAPAFAFALGARRSAPYAAFLVAPAAAWLAYLIHTGGTR
>NC_021173.1|WP_006026552.1|2513043_2513511_-|pilus-assembly-protein
MMRALGRFRSPRRQRGATAIEFAILFPLFFLILYGIVTYGMIFAAQQSLTLAATEGARAALNYQVAQTQAAALGLRAAAACTAANNLTGWLSGATCTTSSNYTCSYDSTMFCIQVTVTYPYAANPLVPAVALFDAVLPTTLTSRATVQINPTNII
>NC_021173.1|WP_015602285.1|2512044_2512956_-|Flp-pilus-assembly-protein-CpaB
MANHLTKIIAVLLIGIAILLGLYAWVLGRKPAPVAPAAAPAAATAMVPVVVAARALPAGQPIPADALKVQQTPTPIAGAFPNPTLVTGRIPASDIVAQAPVLESELMSGLADQIAPGERAVAIKVDDTNAVGNRLRPGNFVDVFVNLKREGGFGATGAEIAQTQARLLLSRVRVLSFGDATADRDGTPGPTGAGARTAVLAVPTAQVDALTLAEASGRLVLALRSPRDEDVAAQTVAIRAPGGAGASNQAAAGLVLSALSGGGASAQTARAAPAPARVTAAAAPRAGGGIEVIRGGRAETVAY
>NC_021173.1|WP_006026554.1|2510655_2511981_-|type-II-and-III-secretion-system-protein-family-protein
MKNKLIAWAMAFGVLLSFAAQAAEMGAIELTTGAQRQIAVGRGVQRVAIGDPNVADVLVIKGGRGGVLLVAKAAGSTSLMVWERGRDEPAVYTVDVVSGAARALLDGGAPGVRAYDGTAVVSGSAATLDAHARALAVGKGMAGKGGGVVDASTVGGKNVVQVDVRVVEFSRSVLKQAGLNFFKQNNGFTFGSFAPAGLASVTGGGTSSMSVSANIPIASAFNLVVGSATRGLFADLSILEANNLARVLAQPTLVALSGQSASFLAGGEIPVPVPQSLGTISIDWKPYGVGLTLTPTVLSPRRIALKVAPESSQLDFVHSITINGVTVPALTTRRADTTVELGDGESFVIGGLIDRETTSNVDKVPFLGDLPIIGTFFKHLSYQQNDKELVIIVTPHLVAPIAKNASLPATPGELSEQRDGPVWRSYLGGALSPDAGPGFSK
>NC_021173.1|WP_015601278.1|2509350_2510589_-|transcriptional-regulator
MNARTQSLAEPAVTDYFVCASPHGEHVRWLAQTLVSAGAVESAPLEPAALAQRIAGLNPVLVFVDFSGGRAQAASAAAAAVRVSHPGLPIVALGSLGEPESALAALRAGVRDFIDFSAPAEDALRITRGLLDHVGEQPSRHGRLIALLGARAGMGASTLAANLSVLVQKRSAALGRQTALVDLGLPAGDGALFLNTRCEFDFVEAVRNLRRFDRTFVNTALARHPSGVALTSLPPSLTGLRDVSYASCVGLLNRLRAFFDCQIVDLGGFSNRDFVAQTANAADESWLLCDQGVASVVSAAELLESLRDAGVDTDNVRLVVNQYDPALGLAPAQIAERLGLALAATLPSRRVPIGHAANQGKLIVDAAERDPYVRALEPLVERATGGTGAAAPRPAGGFSALRRFIQPTSKRS
>NC_021173.1|WP_015600967.1|2508006_2509347_-|CpaF-family-protein
MAHDIQFADGATPFSQTQQFHDIKNAAHEHLLTRIEELGAEFGRWSRQAINQFVDLEIDSFVRLRRIPLNENEVRAVAQALTKELAGFGPIEDLLADPHVEDILINGYSDVYVSKHGILTKLPVRFTDNAHLLRIVRRILAPIGRRLDESNPMVDARLPDGGRVNVVIEPLSIDGPVVSIRKFRKDPLKPADLLANGTFNDEIGALLEAAVAARCNILVSGGTSSGKTSLLNALAFHIPEVERVVTIEDTAELSLNHPHVVRLESRPGGFDGTGVVSIRDLLRNTLRMRPDRIIVGEVRGGEVLEMMQAMNTGHDGSMGTIHASSPRECLYRLEMLAGFAGFQGTESSLRRQIANAVDFIVQIGRLSNGRRRILSVTEVTGLSDNIIATQELYRYEPRVNVDGDETDAWESLGIHPHSPKLARFRQALAGGGFGGEPYGRGGGFNV
>NC_021173.1|WP_015600665.1|2507018_2508014_-|type-II-secretion-system-(T2SS),-F-family-protein
MSSAALWALALALLCVAGALALWRRGAANKERAHAARYIDSRLEPGARPGAPPKMPAAAEPKRAAAVPAAGAPAAKPAEGLARWRERAADAWLNVSNRAGVSEIRTPLIALVAATAVATLWAGLRGGLLAAVAAFVAGATLVVFWLVSRMQKRRLRIVRQLPSFLDGIVRLVTLGNSVPAAFQATLQTTEAPLRGCLDHVSRMLRSGVEIDRAMVYVATLYRIKEFELVGSVLRLSVKYGGRADVMLDRMAVFMRDLEQAERELVAMSAETRLSAWVLGALPVGIGSFVIATNPKYFSAMWLDPMGRQLVYLAFILQVAGGYWLYRLARLR
>NC_021173.1|WP_015600771.1|2505993_2507013_-|type-II-secretion-system-F-family-protein
MDPSRLGAIALVLGSIGVLMLAGLAIMQAVLARRTGRTLADALDQRAAALEAAAARAAAGAESAVGAARASAADAAPDECRPRFATLLDRAGKFGMRLLDTRLGKQIVAEEDRMLLEQCGYVDAHTRGVFLSARIACAIALPAAVALAGGETVRTHLTAWVALCVIAGFMLPKIYVRRRAAARRQSVVDEMPLLVDMLRLLQGVGLSLDQSIQVVTNDFKGMLPVLSSELGIAQRQFVAGRTREQSLQRLATSFDNEDLRAIVRLLIQVDKHGGAVQEPLKQFGDRLREVRRAMLRERIGRLTVKMTGVMILTLLPALFIVTAGPGMLAVTHALTAARR
>NC_021173.1|WP_041861705.1|2505042_2505957_-|pilus-assembly-protein
MRRSSFSPMTTAALAALALSLAACGAFKESGYGIGAQAERAALMQAAADRNATPDTPGMYLGLIGRMQSQGLHYASLAHIDAYEKQYGASPDTILLRADALRATDQPAASTVAYRQLLGTPLAARGYRGLGLLAGASGDFDAASQALAQASALAPTDSLTLSDLAYARMRSGDVGGARVPLMKAAELDQNNPKILSNLALFLLATGQTRDALGLMNQLKLAPAVRTEIRNDATKIAAASRARQRALARPGAPGAAAVAGMAIAANAAGSSGGAAASRGAVAAPVAAATAPAFEPTVPLLQRFSQ
>NC_021173.1|WP_015602058.1|2516592_2517855_+|collagen-like-triple-helix-repeat-containing-protein
MNQQRFVPSFALAAWRVPLTALATACALAACGGSDVTAPPSAGGSTSGTSGTSGTSGTSGTSGTAGTSGVVNTLGKTATDLGNTIGSTSVPGLGSGVTQGVGATVGSTGGIVNAAADALSNGLGQIGSTQNPVGTTVAGLGNVVSAASNTVQGLSQTVQALGTGPLAPLSPVTTPVAGALATAANGVNAAGTMLGNALSTGPVQQITQPISSAVTPLVITAGQVTQTVGTTTGVGQPVSGLLQQVGGAISSAGKQIAGTSPSQPLVGDVGQLVSAVGNTVTNAGGLVNPAAPNGAAPIPGLITSLVGGSTATVATGSGTSSGSTLGSPLSGLLSSLGGGALPTGSLGGSAVSGGASNPLAPITSLASGGTSAGANPLAPVTGLLNPLTGTLSGSTSSTGGATGLLAPVTGTLGTLGSFGK
>NC_021173.1|WP_015602187.1|2518004_2519684_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MKSRHDSWMLLLALVAAAGAAHAQSRSGGNPLEALPQINTPSKPSVTVQVAPQEVQVQALLARHLTPTSFQVEGVRSIPFEEISQRFTPLVGKDITIGQLIETANGVTKLYQERGYALSFAFVPAQTFEGGVVRVTVVEGYVANLKITGRPGAMEPKVRAIAAHIMDDRPLRRATFERYVNTFGLLPGVTVKANVPPPQNTDGATTLELNVDRKPINVSAGLNTNNPGVQGLFTVTENGLTSLGEQMSISALFPKGPNNQTYVSFSGAVPIGSNGLVTRLDASHYRGNPSVDQTVLPNVQRTVINDKLGLSASYPLMLSNQRSLLGTVSGYASHNEDRYQNRSTGAMIGMRSQVRVLQMQLDYTSVQPKQVQKLSFNVAKAFDILGASKSGFTNLPGVTTTNPASTTFVRTGATFAQTNEWPFKIGSTVQLTGQYSPDSLPTTEQISFGAQRFALGYQPGETSGDSGWGASFELNRAFTPGFTYLKNITPYIAYDMARVYLHSGTPVPRRLSSVGLGVRLTDSRFYNLDVSIAKPVGDAPIESASRSPRVNASFSYQLY
>NC_021173.1|WP_009912629.1|2519793_2519925_+|hypothetical-protein
MYQTPRADSRILRKARIHRRPTQTARGLTKTTSCDPRRKTCFK
>NC_021173.1|WP_009912631.1|2519912_2520374_+|DUF2147-domain-containing-protein
MFQMTRSLRSITVAGALLACAASAFAQADSPIGTWQTIDDHTGKPKALVQITADSAGELSGKVLKGLGENDTPDRRCTACTDERKDQLIKGMTIIKAMKKDGEGWDGGNILDPENGKVYKCKMKLEEGGQKLIVRGYIGVSLLGRSQTWMRAQ
>NC_021173.1|WP_006026545.1|2520521_2520932_-|transposase
MTPYRDITDEEWQRVAPLLPELRPRKELRGRPLADTRAVLNGVLWVIYSGANWSAMPRRFPAYQTCHRRFKAWHESGALKRVLVELFGTQSDDLCELMAMRMRTHARSKAAQARSGAASTATSPAPRHEHSLEHVA
>NC_021173.1|WP_075644846.1|2520903_2521110_-|hypothetical-protein
MIRFARRAPRTTRPEFENARRRLTSVNSVLTILKSARVVYSTPVRLDIVAVMFFMNGEAHDAVSRYYR
>NC_021173.1|WP_006026544.1|2521106_2522204_-|cell-division-protein-ZapE
MNVTEYYEHELKTRGYQSDAAQRAAVERLQRCYGEWVAYKARRSNAFKKLVIRPDLPRGVYMWGGVGRGKSFLMDSFYAVVPVQRKTRLHFHEFMREVHRELEELKGQADPLDELARRIAKRYRLICFDEFHVSDIADAMILYRLLDRLFSNGVQFVMTSNYDPDDLYPDGLHRDRMLPAIALLKERLDVLNVDAGVDYRQRTLTQVRMYHTPLGAQADRELRHAFAQLAAVPDENPILHIEKREIKALRRADGVVWFDFATLCGGPRSQNDYLELASRFHAIVLSDVPQMSPRMASEARRFTWLIDVLYDHKVKLLMSAAVAADDLYVEGPMANEFSRTVSRIVEMQSKEYLEAPRRLIDTSLT
>NC_021173.1|WP_015601780.1|2522311_2523742_-|dihydrolipoyl-dehydrogenase
MSKEFDVVVIGAGPGGYIAAIRAAQLGKTVACIEKWKNPAGALKLGGTCLNVGCIPSKALLASSEEFENAQHHLADHGISVDGVKMDVAKMLARKDGIVEKMTGGIEFLFKKNKITWLKGHGKFTGKTDAGVTIEVSGEGETEVVTAKNVIIATGSKARHLPNVPVDNKIVADNEGALTFDTVPKKLAVIGAGVIGLELGSVWRRLGAEVTVLEALPAFLGAADEALAKEAAKLFKKQGLDIHLGVKIDEVKTGANGVSIAYTDKDGNAKTLDADRLIVSVGRVPNTENLGLEAIGLKANERGFIDVDDHCRTAVPNVYAIGDVVRGPMLAHKAEDEGVLVAEVIDGQKPHIDYNCIPWVIYTYPEIAWVGKTEQQLKAEGREIKSGRFPFSINGRALGMNAPDGFVKMIADAKTDELLGVHVIAANASDLIAEAVVAMEFKAASEDVARICHPHPSMSEVMREAALAVDKRSLNS
>NC_021173.1|WP_015601426.1|2523841_2525119_-|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase
MAIVEVKVPQLSESVSEATMLQWKKKPGEAVAQDEILIELETDKVVLEVPAPAAGVLAQVLQNDGDTVVADQVIATIDTEAKAGAAEAAAGAAEVKPAAAPAAAPAPAAQPAAAAASSAAAASPAASKLMAEKGIGAADVAGSGRDGRITKGDVLSAGSAPKAAAAPAQALAAAKPSLPEVKVPASATTWLNDRPEQRVPMSRLRARIAERLLESQQTNAILTTFNEVNMQPVMDLRAKYKDKFEKEHGVKLGFMSFFVKAAVHALKKFPLVNASIDGNDIVYHGYFDIGIAVGSPRGLVVPILRNADQMSLADIEKKIAEFGQKAKDGKLSIEEMTGGTFSISNGGVFGSMLSTPIINPPQSAILGVHATKERPVVENGQIVIRPINYLALSYDHRIIDGREAVLSLVAMKDALEDPARLLLDL
>NC_021173.1|WP_015601625.1|2525256_2528121_-|2-oxoglutarate-dehydrogenase-E1-component
MSDVMKQFQLNSYLFGGNASYVEELYEAYLDNPASVPDNWREYFDALQNVPATDGSSASDVAHNPIVESFAQRAKANAFIPRESGGNLATARKQVHVQSLISAYRFLGSQWANLDPLKRRERPAIPELEPAFYDFSEADLDQTFSASNLYFGFEQASLRDIVKGLRDTYCGTIGVEFMYISDPEQKRWWQERLESSHATPNFSADKKKHILNRLTAAEGLERYLHTKYVGQKRFSLEGGESFIASMDEVVQRAGSKGVQEIVIGMAHRGRLNVLVNTLGKMPADLFAEFEGKHVDDLPAGDVKYHKGFSSDIATEGGPVHLSLAFNPSHLEIVNPVVEGSAKARMDRRGDADGLQVLPVQIHGDAAFAGQGVVMETLNLAQTRGYGTHGTLHIVINNQIGFTTSDPRDARSTLYCTDVVKMIEAPVLHVNGDDPEAVVLATQIAIDYRMQFHKDVVIDIVCFRKLGHNEQDTPAVTQPLMYKKIAQHPGTRALYAEKLAQQGVISAEDADGFVKAYRKAMDDGHHTVDPVLSNYKSKYAVDWMPFLNRKWTDAADTAVPLAELKRLGERITTVPQNFKVHPLVERVINDRRNMARGDQPLDWGMGEHLAYASLVASGYAVRLTGQDSGRGTFTHRHAVLHDQNRERWNDGTYVPLQNISEGQAKFNVIDSVLSEEAVLGFEYGYSTAEPNTLVLWEAQFGDFANGAQVVIDQFISSGEVKWGRVSGLTMLLPHGYEGQGPEHSSARIERYLQLCAEHNMQVVQPTTPAQIFHLLRRQMIRLFRKPLIVATPKSLLRHKEAVSDLSELAKGSFQPVLGEVDGGIDAKKVKRVIACSGRVYYDLVAHRREAKANDAAIVRIEQLYPFAHKQFEAEMKKYENATEVVWVQDEPQNQGPWFYVEHHLKEGMKEGQKLAYSGRPASASPAVGYYAKHYEQQKALIEGAFGRLKSASVAK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	KT221034	Streptomyces phage SF3, complete genome	17567-17596	6	0.8
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	KT221033	Streptomyces phage SF1, complete genome	35267-35296	6	0.8
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1318119-1318148	6	0.8
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	786403-786432	6	0.8
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	466158-466187	6	0.8
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	232270-232299	7	0.767
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	NC_015724	Cupriavidus necator N-1 plasmid pBB2, complete sequence	158018-158047	7	0.767
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	MH727550	Corynebacterium phage Juicebox, complete genome	16187-16216	7	0.767
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	119078-119107	8	0.733
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	119078-119107	8	0.733
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	121970-121999	8	0.733
NC_021173_1	1.2\|2516150\|30\|NC_021173\|PILER-CR	2516150-2516179	30	NZ_CP021004	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6166 plasmid pE, complete sequence	33294-33323	8	0.733

1. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to KT221034 (Streptomyces phage SF3, complete genome) position: , mismatch: 6, identity: 0.8

cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
gcggggcgcgctctcgcgcgccgcgggcgg	Protospacer
   ***.********* ***********.*

2. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to KT221033 (Streptomyces phage SF1, complete genome) position: , mismatch: 6, identity: 0.8

cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
gcggggcgcgctctcgcgcgccgcgggcgg	Protospacer
   ***.********* ***********.*

3. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
cacgggtgcgctcgcgggcgccaagtgcga	Protospacer
************* ********. * **..

4. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.8

-cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
ctacctgt-cgctctcgcgcgccgcgggcac	Protospacer
 .**  ** ******** ************

5. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 6, identity: 0.8

cacgggtgcgctctcgggcgccg---cgggcag	CRISPR spacer
gacggctgcgctctcgggcgccatctcggg---	Protospacer
 **** ****************.   ****

6. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 7, identity: 0.767

cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
gccgccggcgctctccggcgccgccggcag	Protospacer
  **   ******** ******** *****

7. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to NC_015724 (Cupriavidus necator N-1 plasmid pBB2, complete sequence) position: , mismatch: 7, identity: 0.767

cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
gccgcccgcgctctccggcgccgccggcag	Protospacer
  **  .******** ******** *****

8. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to MH727550 (Corynebacterium phage Juicebox, complete genome) position: , mismatch: 7, identity: 0.767

cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
gaaggccgcggtctcgggcgccgcgggccc	Protospacer
 * ** .*** *****************

9. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.733

cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
cgcgggtgcggtctcggtcgccgcgtcggt	Protospacer
*.******** ****** *******   .

10. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.733

cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
cgcgggtgcggtctcggtcgccgcgtcggt	Protospacer
*.******** ****** *******   .

11. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.733

cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
cgcgggtgcggtctcggtcgccgcgtcggt	Protospacer
*.******** ****** *******   .

12. spacer 1.2|2516150|30|NC_021173|PILER-CR matches to NZ_CP021004 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6166 plasmid pE, complete sequence) position: , mismatch: 8, identity: 0.733

cacgggtgcgctctcgggcgccgcgggcag	CRISPR spacer
taagggtgcgctctcggccgctgcggtggc	Protospacer
.* ************** ***.****  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

246324 : 307537

Burkholderia_phage(27.27%)

portal,transposase,holin,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041861551.1\|246324_247587_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_006029871.1\|248694_249810_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_155246022.1\|250154_250316_-	hypothetical protein	NA	NA	NA	NA
WP_015602062.1\|251204_252110_-\|plate	baseplate assembly protein	K4NZR5	Burkholderia_phage	7.2e-157	95.7
WP_041861800.1\|252106_252469_-\|plate	baseplate assembly protein	K4PAX6	Burkholderia_phage	1.0e-53	85.0
WP_075644724.1\|253679_254135_-	hypothetical protein	F2Y385	Organic_Lake_phycodnavirus	2.3e-18	38.0
WP_041861553.1\|255297_256335_+\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	4.8e-197	96.8
WP_004202809.1\|256378_256735_-	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.9e-42	100.0
WP_015600654.1\|256948_258043_-	DUF3396 domain-containing protein	A9YX32	Burkholderia_phage	1.8e-93	60.6
WP_015600472.1\|258772_259309_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	4.1e-59	62.9
WP_138110399.1\|259470_259758_-	hypothetical protein	NA	NA	NA	NA
WP_015601433.1\|259829_259979_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015601016.1\|260111_260336_-	hypothetical protein	NA	NA	NA	NA
WP_015601972.1\|261098_261416_+	hypothetical protein	NA	NA	NA	NA
WP_015601293.1\|261939_262584_+	chitin-binding protein	NA	NA	NA	NA
WP_015600518.1\|262775_264440_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_015602085.1\|264660_266466_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.9e-08	52.6
WP_009913936.1\|266590_267406_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_009913933.1\|268131_268809_+	curli production assembly protein CsgG	NA	NA	NA	NA
WP_015602080.1\|268869_269289_+	DUF4810 domain-containing protein	NA	NA	NA	NA
WP_075644930.1\|269285_269972_+	DUF799 domain-containing protein	NA	NA	NA	NA
WP_138110401.1\|270054_270243_+	hypothetical protein	NA	NA	NA	NA
WP_075644931.1\|270197_271892_+	acid phosphatase	NA	NA	NA	NA
WP_138110403.1\|272778_272958_+	hypothetical protein	NA	NA	NA	NA
WP_015600857.1\|273057_273459_+	hypothetical protein	NA	NA	NA	NA
WP_138110405.1\|273503_273821_+	hypothetical protein	NA	NA	NA	NA
WP_041861554.1\|273851_274166_-	flagellar protein FliT	NA	NA	NA	NA
WP_015600718.1\|274179_275700_-	flagellar filament capping protein FliD	NA	NA	NA	NA
WP_006023840.1\|275849_277019_-	flagellin	NA	NA	NA	NA
WP_004198205.1\|277580_277793_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_015602144.1\|278187_278796_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_015600856.1\|278947_279838_+	putative N-acetylglucosamine kinase	NA	NA	NA	NA
WP_006023835.1\|279949_280771_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_009913923.1\|280894_281599_-	aquaporin Z	NA	NA	NA	NA
WP_006023832.1\|281905_282202_+	H-NS histone family protein	NA	NA	NA	NA
WP_006023831.1\|282305_283370_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_075644726.1\|283439_283613_+	hypothetical protein	NA	NA	NA	NA
WP_075644727.1\|283616_284285_+	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
WP_015601808.1\|284378_284930_+	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
WP_009913920.1\|285103_285964_+	flagellar motor stator protein MotA	NA	NA	NA	NA
WP_006023827.1\|285980_287003_+	flagellar motor protein MotB	NA	NA	NA	NA
WP_006023826.1\|287033_287414_+	response regulator	NA	NA	NA	NA
WP_015600565.1\|287445_289725_+	chemotaxis protein CheA	NA	NA	NA	NA
WP_006023824.1\|289755_290283_+	chemotaxis protein CheW	NA	NA	NA	NA
WP_015600241.1\|290323_292333_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	5.9e-10	57.7
WP_015602267.1\|292336_293278_+	chemotaxis protein methyltransferase	NA	NA	NA	NA
WP_006023821.1\|293274_293979_+	chemoreceptor glutamine deamidase CheD	NA	NA	NA	NA
WP_041861556.1\|293975_295079_+	chemotaxis response regulator protein-glutamate methylesterase	NA	NA	NA	NA
WP_004185006.1\|295154_295550_+	chemotaxis protein CheY	Q56AR1	Bacillus_thuringiensis_phage	2.7e-07	32.8
WP_015601094.1\|295551_296280_+	protein phosphatase CheZ	NA	NA	NA	NA
WP_006023816.1\|296478_296982_+	DUF2844 domain-containing protein	NA	NA	NA	NA
WP_015601888.1\|297004_298288_+	DUF3443 domain-containing protein	NA	NA	NA	NA
WP_075644932.1\|298647_299865_+	flagellar type III secretion system protein FlhB	NA	NA	NA	NA
WP_015602362.1\|299861_301964_+	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_015600910.1\|301960_303727_+	flagellar biosynthesis protein FlhF	NA	NA	NA	NA
WP_006023810.1\|303719_304532_+	flagellar biosynthesis protein FlhG	NA	NA	NA	NA
WP_006023809.1\|304553_305288_+	RNA polymerase sigma factor FliA	NA	NA	NA	NA
WP_015601770.1\|305597_307019_+	adenosylhomocysteinase	S4VPF6	Pandoravirus	1.3e-43	29.5
WP_006023807.1\|307183_307537_+\|holin	phage holin family protein	NA	NA	NA	NA

DBSCAN-SWA_2

485564 : 532622

Liberibacter_phage(40.0%)

protease,transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075644733.1\|485564_486074_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	8.5e-22	51.9
WP_015601523.1\|486366_487569_+	DUF4102 domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.3e-105	49.6
WP_015601576.1\|487576_488428_+	hypothetical protein	NA	NA	NA	NA
WP_096746704.1\|488363_489014_-	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_015600629.1\|490004_491600_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_015601012.1\|491649_491940_-	hypothetical protein	NA	NA	NA	NA
WP_015600837.1\|491988_492261_-	hypothetical protein	NA	NA	NA	NA
WP_015602378.1\|492257_492467_-	hypothetical protein	NA	NA	NA	NA
WP_015601042.1\|493517_494573_-	hypothetical protein	NA	NA	NA	NA
WP_015601496.1\|494733_496515_-	hypothetical protein	A0A1L7N0M1	Ralstonia_phage	7.3e-52	32.4
WP_041861568.1\|496690_497032_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015600692.1\|497397_498003_+	putative lipoprotein	NA	NA	NA	NA
WP_096746686.1\|498004_498619_+	hypothetical protein	NA	NA	NA	NA
WP_138110407.1\|498689_498983_+	hypothetical protein	NA	NA	NA	NA
WP_015601920.1\|499409_500051_-	hypothetical protein	NA	NA	NA	NA
WP_015602002.1\|500052_500352_-	hypothetical protein	NA	NA	NA	NA
WP_015600590.1\|500462_501269_-	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_015601312.1\|501337_502414_-	hypothetical protein	NA	NA	NA	NA
WP_015601601.1\|502410_503316_-	hypothetical protein	NA	NA	NA	NA
WP_015601628.1\|503371_503599_-	hypothetical protein	NA	NA	NA	NA
WP_015601499.1\|503611_504607_-	phage-type endonuclease	A6XMH8	Bacillus_virus	2.0e-51	39.1
WP_041861811.1\|504684_505650_-	DUF932 domain-containing protein	A0A0H4INH5	Stenotrophomonas_phage	5.0e-55	40.5
WP_006029871.1\|505741_506857_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_102812160.1\|507012_507231_-	hypothetical protein	NA	NA	NA	NA
WP_015600937.1\|507992_508190_+	hypothetical protein	NA	NA	NA	NA
WP_015602385.1\|508186_509689_+	SAM-dependent DNA methyltransferase	A0A220A2U4	Liberibacter_phage	9.8e-151	53.9
WP_041861812.1\|509778_511317_+	SAM-dependent DNA methyltransferase	A0A220A2U5	Liberibacter_phage	1.8e-139	57.1
WP_096746687.1\|511354_512512_+	restriction endonuclease	A0A240FAT6	Liberibacter_phage	1.1e-21	37.6
WP_015601397.1\|512501_515486_+	HsdR family type I site-specific deoxyribonuclease	A0A220A398	Liberibacter_phage	1.3e-210	40.8
WP_015601243.1\|515495_518357_+	PHP domain protein	A0A1B1IUG5	uncultured_Mediterranean_phage	1.5e-14	22.9
WP_015601963.1\|518358_519627_+	divergent AAA domain protein	NA	NA	NA	NA
WP_011883089.1\|520405_520891_-	hypothetical protein	NA	NA	NA	NA
WP_015602426.1\|520902_522036_-	HigA family addiction module antidote protein	NA	NA	NA	NA
WP_006029380.1\|522576_523362_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_006029381.1\|523358_524705_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_015600452.1\|524813_525428_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_015601514.1\|525801_526467_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_006029385.1\|526503_527022_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_006029386.1\|527039_528530_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_006029387.1\|528602_529106_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_075644735.1\|529133_529640_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_075644942.1\|529731_531558_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_015601719.1\|531521_532622_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_3

843993 : 853168

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015601574.1\|843993_845934_+	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	8.5e-147	50.3
WP_015601848.1\|846197_847331_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	9.1e-24	38.2
WP_015602361.1\|847362_849324_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	3.8e-54	32.3
WP_006025369.1\|849489_850305_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	9.7e-36	32.1
WP_015602420.1\|850369_851053_-	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	6.7e-06	26.0
WP_006025371.1\|851049_851577_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_015602021.1\|851614_853168_-	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2

DBSCAN-SWA_4

1209763 : 1218198

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015600060.1\|1209763_1211164_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.2e-78	38.3
WP_015601685.1\|1211195_1212119_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	5.7e-16	27.5
WP_006025721.1\|1212177_1213170_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	1.0e-26	30.6
WP_015601656.1\|1213241_1213559_+	hypothetical protein	NA	NA	NA	NA
WP_009916396.1\|1213897_1214800_+	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	2.3e-54	40.2
WP_096746693.1\|1214894_1216172_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_006025725.1\|1216299_1217223_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	2.4e-43	35.9
WP_041861829.1\|1217343_1218198_-	alpha/beta hydrolase	A7XCB7	Tanapox_virus	3.3e-18	26.4

DBSCAN-SWA_5

1641840 : 1743524

105

Ralstonia_phage(28.95%)

portal,integrase,tRNA,tail,protease,capsid,terminase,head

attL 1682526:1682553|attR 1729863:1729890

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041861634.1\|1641840_1642425_+\|tRNA	tRNA adenosine(34) deaminase TadA	S4VYT2	Pandoravirus	2.2e-05	31.3
WP_015601805.1\|1642478_1643420_+	muramoyltetrapeptide carboxypeptidase	NA	NA	NA	NA
WP_006026108.1\|1643743_1644439_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_075644797.1\|1644552_1646085_+	NCS1 family nucleobase:cation symporter-1	NA	NA	NA	NA
WP_015600169.1\|1646095_1646908_+	aspartate/glutamate racemase family protein	NA	NA	NA	NA
WP_015601713.1\|1647053_1648007_+	allantoinase PuuE	NA	NA	NA	NA
WP_075644798.1\|1648003_1648528_+	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase	NA	NA	NA	NA
WP_006026113.1\|1648651_1649665_+	allantoicase	NA	NA	NA	NA
WP_015601651.1\|1649661_1650174_+	ureidoglycolate lyase	NA	NA	NA	NA
WP_015600419.1\|1650381_1651746_+	hypothetical protein	NA	NA	NA	NA
WP_015600367.1\|1652136_1653339_-	cytochrome c family protein	NA	NA	NA	NA
WP_006026117.1\|1653388_1653748_-	hydroxyisourate hydrolase	NA	NA	NA	NA
WP_015600161.1\|1654239_1655652_+	8-oxoguanine deaminase	A0A291ATQ6	Pandoravirus	1.5e-07	24.4
WP_006026119.1\|1655846_1656776_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_009912804.1\|1657284_1657494_-	dodecin domain-containing protein	NA	NA	NA	NA
WP_015600404.1\|1657635_1658523_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004527255.1\|1658681_1659170_-	hypothetical protein	NA	NA	NA	NA
WP_004192898.1\|1659492_1659924_-	large conductance mechanosensitive channel protein MscL	NA	NA	NA	NA
WP_015600473.1\|1660108_1661317_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_006026123.1\|1661429_1662110_-	PspA/IM30 family protein	NA	NA	NA	NA
WP_075644986.1\|1662379_1662673_-	hypothetical protein	NA	NA	NA	NA
WP_075644800.1\|1662589_1665148_+	penicillin-binding protein 1A	NA	NA	NA	NA
WP_015601734.1\|1665356_1665806_-	DUF3574 domain-containing protein	NA	NA	NA	NA
WP_015601864.1\|1666247_1667279_-	threonine/serine dehydratase	NA	NA	NA	NA
WP_006026127.1\|1667346_1668564_-	acetylornithine deacetylase	NA	NA	NA	NA
WP_015600564.1\|1668881_1669076_+	hypothetical protein	NA	NA	NA	NA
WP_015600462.1\|1669205_1672679_-	transcription-repair coupling factor	NA	NA	NA	NA
WP_015600386.1\|1672796_1673507_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_006026131.1\|1673547_1674036_+	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_006026132.1\|1674227_1674755_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_009912787.1\|1674832_1675381_-	peroxiredoxin	NA	NA	NA	NA
WP_015600436.1\|1675578_1676937_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_004199523.1\|1677029_1677755_-	two-component system response regulator OmpR	W8CYM9	Bacillus_phage	8.1e-34	36.7
WP_009904927.1\|1677842_1678025_+	hypothetical protein	NA	NA	NA	NA
WP_075644801.1\|1677976_1678315_+	hypothetical protein	NA	NA	NA	NA
WP_015601607.1\|1680078_1681332_+	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_006026138.1\|1681390_1682227_-	presqualene diphosphate synthase HpnD	NA	NA	NA	NA
1682526:1682553	attL	NA	NA	NA	NA
WP_009941357.1\|1682715_1683732_+\|integrase	tyrosine-type recombinase/integrase	A0A0A0YR56	Pseudomonas_phage	9.6e-49	39.8
WP_015600418.1\|1683965_1684286_-	hypothetical protein	NA	NA	NA	NA
WP_015600944.1\|1684285_1684555_-	hypothetical protein	NA	NA	NA	NA
WP_015600229.1\|1684568_1685285_-	hypothetical protein	C7BGD6	Burkholderia_phage	6.7e-57	47.1
WP_015600604.1\|1685593_1688995_-	host specificity protein J	Q3HQU5	Burkholderia_phage	0.0e+00	57.1
WP_041861638.1\|1688991_1689567_-\|tail	tail assembly protein	Q8W6T1	Burkholderia_virus	1.9e-46	50.3
WP_015602451.1\|1689563_1690304_-	C40 family peptidase	Q3HQU3	Burkholderia_phage	3.3e-75	54.8
WP_015600135.1\|1690300_1690981_-\|tail	phage minor tail protein L	Q6JIL5	Burkholderia_virus	1.7e-62	53.1
WP_015601347.1\|1691930_1692275_-\|tail	phage tail protein	C7BGC9	Burkholderia_phage	3.7e-13	40.7
WP_041861639.1\|1692271_1695085_-\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	1.8e-20	22.7
WP_075644802.1\|1695081_1695525_-	hypothetical protein	NA	NA	NA	NA
WP_041861641.1\|1695855_1696191_-	hypothetical protein	NA	NA	NA	NA
WP_015601485.1\|1696339_1696777_-\|tail	phage major tail 2 family protein	NA	NA	NA	NA
WP_015601472.1\|1696776_1697133_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_075644803.1\|1697125_1697464_-\|head	phage head closure protein	NA	NA	NA	NA
WP_015600215.1\|1697496_1697787_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_015600130.1\|1697779_1699117_-\|portal	phage portal protein	A0A0R6PHI5	Moraxella_phage	4.3e-81	43.6
WP_015602462.1\|1699113_1699284_-	hypothetical protein	NA	NA	NA	NA
WP_015600962.1\|1699343_1700678_-\|capsid	phage major capsid protein	S4TNE3	Salmonella_phage	3.1e-79	41.4
WP_075644804.1\|1700691_1701330_-	peptidase U35	A0A0R6PHN0	Moraxella_phage	7.9e-33	42.9
WP_015601176.1\|1701292_1702882_-\|terminase	terminase large subunit	Q9MCV7	Escherichia_phage	6.5e-185	65.1
WP_155246026.1\|1702878_1703286_-	TerS protein	A0A0F7L441	uncultured_marine_virus	2.2e-28	51.9
WP_041861642.1\|1704192_1704675_+	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_138110425.1\|1705500_1705899_-	DUF2628 domain-containing protein	NA	NA	NA	NA
WP_015601215.1\|1705947_1706592_-	S24 family peptidase	A5X9F5	Aeromonas_virus	9.7e-15	28.8
WP_138110427.1\|1707060_1707507_+	hypothetical protein	NA	NA	NA	NA
WP_015600095.1\|1707724_1708450_+	phage antirepressor KilAC domain protein	B3VGL7	Mycobacterium_virus	1.4e-33	50.3
WP_015600721.1\|1708503_1708737_+	hypothetical protein	NA	NA	NA	NA
WP_015600873.1\|1709085_1709712_+	hypothetical protein	NA	NA	NA	NA
WP_051139202.1\|1710131_1710338_+	hypothetical protein	B5BTU9	Ralstonia_phage	4.2e-20	74.6
WP_015600868.1\|1710636_1711008_+	hypothetical protein	NA	NA	NA	NA
WP_015600811.1\|1711007_1711259_+	hypothetical protein	NA	NA	NA	NA
WP_015601324.1\|1711275_1711563_+	hypothetical protein	NA	NA	NA	NA
WP_015600725.1\|1711559_1711766_+	Fragile-X-F family protein	NA	NA	NA	NA
WP_015602193.1\|1712033_1712606_+	toprim domain protein	A0A077KVN4	Ralstonia_phage	1.3e-47	52.7
WP_041861643.1\|1712721_1714017_+	AAA family ATPase	A0A068Q6G7	Ralstonia_phage	2.2e-151	61.1
WP_138110429.1\|1713710_1714433_+	hypothetical protein	A0A2I7SBG9	Pseudomonas_phage	3.7e-23	42.2
WP_015600078.1\|1714578_1714851_+	hypothetical protein	NA	NA	NA	NA
WP_015602147.1\|1714953_1715862_+	ATP-dependent DNA ligase	A0A068Q5W4	Ralstonia_phage	1.5e-66	48.1
WP_015601257.1\|1716028_1716589_+	hypothetical protein	A0A192Y8M4	Salmonella_phage	3.5e-37	49.4
WP_041861644.1\|1716611_1719032_+	DNA polymerase A family protein	A0A068Q7T8	Ralstonia_phage	2.3e-303	64.6
WP_015600626.1\|1719052_1719883_+	hypothetical protein	A0A077KTI9	Ralstonia_phage	1.7e-64	55.9
WP_015601124.1\|1719882_1720098_+	hypothetical protein	NA	NA	NA	NA
WP_015600772.1\|1720256_1721030_+	phosphodiesterase I	A0A1L7DQH5	Ralstonia_phage	1.8e-68	52.0
WP_102812144.1\|1721031_1721391_+	hypothetical protein	A0A1L7DQG2	Ralstonia_phage	6.4e-24	58.6
WP_015600542.1\|1721387_1722176_+	RNase H superfamily protein	A0A2P0VPF6	Ralstonia_phage	1.4e-100	66.2
WP_015602387.1\|1722185_1722776_+	DNA polymerase III subunit beta, central domain protein	A0A1L7DQD4	Ralstonia_phage	2.8e-24	40.5
WP_041861645.1\|1722899_1723127_+	hypothetical protein	NA	NA	NA	NA
WP_041861845.1\|1723260_1723563_+	hypothetical protein	D2EBS7	Pseudomonas_phage	1.9e-29	71.1
WP_015602143.1\|1723559_1723751_+	hypothetical protein	NA	NA	NA	NA
WP_015600150.1\|1725035_1727345_+	DNA-dependent RNA polymerase	A0A2R2ZGE5	Ralstonia_phage	2.9e-77	31.4
WP_015601622.1\|1727570_1728260_+	hypothetical protein	Q3HQV2	Burkholderia_phage	1.9e-69	59.0
WP_009941408.1\|1728345_1728537_+	hypothetical protein	NA	NA	NA	NA
WP_102812145.1\|1728619_1728826_+	hypothetical protein	NA	NA	NA	NA
WP_041861647.1\|1729037_1729583_-	lysozyme	A0A0A1I5L5	Burkholderia_phage	2.5e-27	44.2
WP_015600769.1\|1730345_1730807_+	MEKHLA domain-containing protein	NA	NA	NA	NA
1729863:1729890	attR	NA	NA	NA	NA
WP_015600742.1\|1730901_1731525_-	phospholipase D family protein	E9P5Z4	Wolbachia_endosymbiont_wVitA_of_Nasonia_vitripennis_phage	1.4e-18	31.7
WP_096746707.1\|1731725_1732748_-	class II histone deacetylase	A0A2K9L2T7	Tupanvirus	9.3e-36	30.3
WP_015601595.1\|1732883_1734077_-	MFS transporter	NA	NA	NA	NA
WP_015601149.1\|1734100_1735162_-	porin	NA	NA	NA	NA
WP_075644990.1\|1735492_1736641_+	response regulator transcription factor	NA	NA	NA	NA
WP_015600775.1\|1736723_1737713_+	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_006026146.1\|1737794_1738244_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015600780.1\|1738334_1739498_-	glycerate kinase	NA	NA	NA	NA
WP_075644809.1\|1739800_1739926_+	hypothetical protein	NA	NA	NA	NA
WP_015602421.1\|1739945_1741295_+	trigger factor	NA	NA	NA	NA
WP_006026149.1\|1741439_1742093_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.1e-53	57.0
WP_004521258.1\|1742252_1743524_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.4e-134	59.0

DBSCAN-SWA_6

2121904 : 2162906

Burkholderia_virus(56.25%)

lysis,portal,plate,tail,transposase,capsid,terminase,head,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015602418.1\|2121904_2122264_+	type II toxin-antitoxin system HicB family antitoxin	R4JJS9	Burkholderia_phage	2.1e-51	81.5
WP_015600260.1\|2122591_2122921_-	helix-turn-helix domain-containing protein	R4JEU7	Burkholderia_phage	1.2e-53	92.7
WP_015600134.1\|2123153_2123306_+	hypothetical protein	R4JMC2	Burkholderia_phage	1.8e-12	70.0
WP_041861674.1\|2123293_2124163_+	DUF550 domain-containing protein	R4JG80	Burkholderia_phage	1.4e-104	71.8
WP_015601415.1\|2124159_2124660_+	hypothetical protein	NA	NA	NA	NA
WP_015601027.1\|2124690_2124876_+	hypothetical protein	A4JWW7	Burkholderia_virus	8.3e-20	90.2
WP_009897093.1\|2124872_2125094_+	hypothetical protein	A4JWW6	Burkholderia_virus	1.6e-38	100.0
WP_041861676.1\|2125097_2125313_+	hypothetical protein	A4JWW5	Burkholderia_virus	9.7e-28	97.0
WP_006027274.1\|2125321_2125459_+	hypothetical protein	A4JWW4	Burkholderia_virus	6.2e-20	97.8
WP_006027273.1\|2125616_2125835_+	hypothetical protein	NA	NA	NA	NA
WP_015600181.1\|2126087_2127404_+	DNA cytosine methyltransferase	A0A1B0V7P0	Salmonella_phage	2.0e-67	37.6
WP_015601913.1\|2129174_2129381_+	putative gp16, DNA methyltransferase	A4JWW1	Burkholderia_virus	4.0e-31	95.6
WP_015600741.1\|2129380_2131174_+	replication endonuclease	A4JWW0	Burkholderia_virus	0.0e+00	92.0
WP_015600468.1\|2131189_2131456_+	ogr/Delta-like zinc finger family protein	A4JWV9	Burkholderia_virus	8.6e-42	95.3
WP_004532731.1\|2131452_2131659_+	bacteriophage-acquired protein	A4JWV8	Burkholderia_virus	8.7e-34	100.0
WP_075644822.1\|2131745_2132402_+	AAA family ATPase	A4JWV7	Burkholderia_virus	4.2e-114	99.5
WP_041861677.1\|2132635_2132758_+	CopG family transcriptional regulator	A4JWV6	Burkholderia_virus	2.9e-13	97.5
WP_015600440.1\|2132861_2133395_+	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	5.6e-93	96.0
WP_015601730.1\|2133391_2134129_+	VRR-NUC domain-containing protein	A4JWV4	Burkholderia_virus	5.2e-129	96.3
WP_075644823.1\|2134137_2135259_+	DUF3396 domain-containing protein	A4JWV3	Burkholderia_virus	5.5e-215	97.9
WP_075644997.1\|2135915_2136239_+	type II toxin-antitoxin system RelE/ParE family toxin	A4JWV2	Burkholderia_virus	2.4e-54	97.2
WP_004202809.1\|2136241_2136598_+	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.9e-42	100.0
WP_015600601.1\|2136641_2137697_-\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	1.6e-203	97.7
WP_015602129.1\|2137693_2139463_-\|terminase	terminase ATPase subunit family protein	A4JWQ1	Burkholderia_virus	0.0e+00	98.5
WP_041861863.1\|2139641_2140094_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_082252628.1\|2140100_2140625_+	hypothetical protein	NA	NA	NA	NA
WP_075644826.1\|2140698_2141295_+	hypothetical protein	NA	NA	NA	NA
WP_138110445.1\|2141336_2141660_+	hypothetical protein	NA	NA	NA	NA
WP_015602349.1\|2142141_2142951_+\|capsid	GPO family capsid scaffolding protein	K4PAW2	Burkholderia_phage	1.1e-145	98.5
WP_015601766.1\|2142984_2143998_+\|capsid	phage major capsid protein, P2 family	A4JWP9	Burkholderia_virus	3.8e-183	96.1
WP_015600205.1\|2143994_2144684_+\|terminase	terminase endonuclease subunit	K4NX86	Burkholderia_phage	1.0e-115	99.1
WP_015602371.1\|2144783_2145263_+\|head	head completion/stabilization protein	K4NZV5	Burkholderia_phage	5.4e-79	97.5
WP_015601733.1\|2145262_2145514_+	hypothetical protein	K4NXI9	Burkholderia_phage	1.7e-39	98.8
WP_004524438.1\|2145510_2145717_+\|tail	tail protein	K4PAW7	Burkholderia_phage	2.4e-31	100.0
WP_004553021.1\|2145731_2146076_+	membrane protein	K4NZQ3	Burkholderia_phage	6.5e-50	99.1
WP_015602400.1\|2146077_2146350_+\|holin	phage holin family protein	K4NX91	Burkholderia_phage	2.5e-41	98.9
WP_015600152.1\|2146346_2147159_+	DUF3380 domain-containing protein	A4JWZ0	Burkholderia_virus	1.4e-148	98.1
WP_015600594.1\|2147155_2147596_+\|lysis	LysB family phage lysis regulatory protein	K4NXJ2	Burkholderia_phage	1.8e-65	91.8
WP_015601830.1\|2147700_2148117_+\|tail	phage tail protein	A4JWT7	Burkholderia_virus	2.0e-69	96.4
WP_015600143.1\|2148113_2148581_+	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	5.1e-74	94.8
WP_075644827.1\|2149591_2150494_-	site-specific DNA-methyltransferase	A4JWY5	Burkholderia_virus	8.8e-155	93.8
WP_015601241.1\|2150568_2151249_+\|plate	phage baseplate assembly protein V	K4NXJ5	Burkholderia_phage	3.4e-119	96.5
WP_015600511.1\|2151245_2151608_+	lysozyme family protein	K4PAX6	Burkholderia_phage	4.7e-59	95.0
WP_015600644.1\|2151604_2152510_+\|plate	baseplate assembly protein	K4NZR5	Burkholderia_phage	1.2e-156	95.3
WP_015602232.1\|2152502_2153057_+\|tail	phage tail protein I	A4JWT0	Burkholderia_virus	8.7e-97	96.2
WP_075644828.1\|2153058_2155431_+\|tail	phage tail protein	Q45YG3	Burkholderia_virus	0.0e+00	90.6
WP_006027244.1\|2155447_2156119_+\|tail	tail assembly chaperone	A4JWS8	Burkholderia_virus	5.6e-106	97.3
WP_015600222.1\|2156175_2157348_+\|tail	phage tail sheath protein	Q45YG5	Burkholderia_virus	1.3e-219	98.5
WP_015601762.1\|2157363_2157873_+\|tail	phage major tail tube protein	K4NZR9	Burkholderia_phage	9.2e-93	98.2
WP_015600156.1\|2157930_2158275_+\|tail	phage tail assembly protein	K4NXA3	Burkholderia_phage	9.7e-54	98.2
WP_009914998.1\|2158283_2158400_+\|tail	GpE family phage tail protein	A0A089FGX3	Burkholderia_phage	8.3e-10	86.8
WP_075644829.1\|2158396_2161363_+	hypothetical protein	Q45YG8	Burkholderia_virus	0.0e+00	95.3
WP_015601642.1\|2161380_2161806_+\|tail	phage tail protein	A4JWS2	Burkholderia_virus	9.7e-72	98.6
WP_015602174.1\|2161805_2162906_+	phage late control D family protein	K4PAY4	Burkholderia_phage	1.8e-194	96.2

DBSCAN-SWA_7

3208262 : 3219172

Agrobacterium_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006024809.1\|3208262_3210563_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	2.3e-167	42.2
WP_006024808.1\|3210559_3210874_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	1.2e-13	45.8
WP_004196460.1\|3211403_3211607_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_015601231.1\|3211730_3213329_-	multicopper oxidase family protein	NA	NA	NA	NA
WP_006024806.1\|3213499_3214759_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	8.9e-12	63.0
WP_006024805.1\|3215023_3215602_+	pseudouridine synthase	NA	NA	NA	NA
WP_071810810.1\|3215862_3216081_+	hypothetical protein	NA	NA	NA	NA
WP_015601971.1\|3216273_3216783_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	3.2e-13	40.2
WP_006024803.1\|3217057_3219172_+	elongation factor G	E4ZFJ7	Streptococcus_phage	1.5e-56	26.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_021174

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_021173

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection