CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_021214	Thermotoga maritima MSB8, complete sequence	8 crisprs	cas14k,TnpB_regular.1,cas3,DEDDh,csa3,cas14j,WYL,cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,cmr1gr7,cas2,cas1,cas4,cas5,cas7,cas8b1,csx22,csm5gr7,csm4gr5,csm3gr7,csm2gr11,csx1,cas6	0	5	5	0

1. NC_021214

CRISPR-Cas detection and classification

Crispr_ID: NC_021214_1

• CRISPR_ID: NC_021214_1
• CRISPR_location: 412-3105
• CRISPR_type: Orphan
• Repeat_type: III-A
• Spacer_info: 40 spacers

Consensus repeat of NC_021214_1

Consensus_repeat	Method
GTTTCAATACTTCCTTAGAGGTATGGAAAC	PILER-CR
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CRISPRCasFinder
GTTTCAATANTTCCTTAGAGGTATGGAAAC	CRT

spacers of NC_021214_1

>1.1|442|38|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TCTGTGATCTGTTAACGGGGACATCCACACCCAAAATC
>1.2|510|38|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ACTGTCGGAGATGTTCTGCTGTGCATCGTCGAGAGTTT
>1.3|578|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ATATAAGCCTTTTCCAGTCTTCGGGGGACATTTCCCA
>1.4|645|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ATGCGAGCACTGTCCTCTCCAACATCCATATACACCG
>1.5|712|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CATACTCCAGCATCAAGCAACTTGCTGGCGAAATTTC
>1.6|779|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ATCCATATCAACGTTGCATATTCTCGTTGATAAAAA
>1.7|845|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
GCGACAAGCCCACGTTCAGGCACGAGGTGTTCCCTGA
>1.8|912|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
AAGTTTTACCTTTTCTCAGACAACTTCAACTGGAAAA
>1.9|979|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TCGATTATTTCTTTTACAAAGACATGCGATCATACAA
>1.10|1046|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TATACGTTGTAGAAATCGCAAAGGTGGTGATGTTA
>1.11|1111|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TCTCGAATCCGATATAATCATATTTCCTTATTATAT
>1.12|1177|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CCGCATCTCGTAGGTATTGCTTGCCTTCTGTTCCCTT
>1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TAAACTTGTAAATCCTTTTGAAGACTTAGAACAAC
>1.14|1309|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
GAAACGCCCGCAAACGCTCATCACAAGCCCGTTTCC
>1.15|1375|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TTGAGTATAAAATCTTCTTCTGATAATGACAAAACA
>1.16|1441|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TGCTTCTATTACTCTTTGTAGCACGTTCGTGAACTCA
>1.17|1508|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TCGATAATCTCAGATGCCTCGCCTCAATTTCAATTG
>1.18|1574|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CTCCACAATGAAAAGAATAGATGGTAAGGTGTGCTT
>1.19|1640|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CTACTATCTTCTATATATATATTTTTGTTTTTGTTTT
>1.20|1707|38|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CTATTTCCCTCTGCCGTCTCTTCGAAATGATCACCTCT
>1.21|1775|38|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TGTGAAGGCGTATGAGGTGGAGGATATTCCTGCAATTG
>1.22|1843|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TTTTTCCAGCATCTTCTTCACGAAGTACGTCTTCATC
>1.23|1910|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
GCGATGTTGCGAGAACGATGAAAGATTTGTATGAAC
>1.24|1976|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TTGTCGAACTCTTTGGTACTTCCATCCGGATACATCT
>1.25|2043|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
GAGTAGTACAGAGGAGAGAGATGCAGATATCCACGAC
>1.26|2110|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CTCGATCGCTTGTGGTATCTCTGTCTGTGCGAGCT
>1.27|2175|39|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TTGTGATGATGTCGCCAAGCTTTAGGGGGACATCTGTTT
>1.28|2244|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CTGATCTAGCCGTCCGGCCAGTCACAGGTTGAGATA
>1.29|2310|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ATGTATTGCAAGGAAAAGCAAAAATAAGATTCGACAG
>1.30|2377|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TCGAACTCGAAGAGGCCTATGCACCTGTCCAGCCTAT
>1.31|2444|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ATCCTCCTTACTTTGGCCGACACCGTTCGTCCGTTT
>1.32|2510|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CTTCAAGCCATACTAATATTGCGTATTCTCTTCTCA
>1.33|2576|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
AAAAGCCTACGAAGGGCTTCGAGTACCACCAGCTTTT
>1.34|2643|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
GGGCTGAAAAATTTCCCATTTCGTTTTATCACCTCCT
>1.35|2710|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CAAGGGGAGGATGATACTGAATGGATAGGGGAACTCA
>1.36|2777|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ACCATTCATCCATTACAACCTCTTTGCCTCTAATTT
>1.37|2843|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TGATGTCTTCCCATTGTTTCGTGTTGTCAAACACCT
>1.38|2909|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TAAAGCATACGCTCCAAAACGTGAACAAATTCTCTCA
>1.39|2976|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT
AGTTGGACGACGATCTTGTATTCATAAATGTTGTT
>1.40|3041|35|NC_021214|CRISPRCasFinder,CRT
TAAGACATTCTTTCGCTAAGAAAATCTAATAGTTT

CRISPR arrays and Neighbor proteins around NC_021214_1

CRISPR arrays

The CRISPR arrays of NC_021214_1

>merge|NC_021214|1|412-3105|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATACTTCCTTAGAGGTATGGAAACTCTGTGATCTGTTAACGGGGACATCCACACCCAAAATCGTTTCAATACTTCCTTAGAGGTATGGAAACACTGTCGGAGATGTTCTGCTGTGCATCGTCGAGAGTTTGTTTCAATACTTCCTTAGAGGTATGGAAACATATAAGCCTTTTCCAGTCTTCGGGGGACATTTCCCAGTTTCAATACTTCCTTAGAGGTATGGAAACATGCGAGCACTGTCCTCTCCAACATCCATATACACCGGTTTCAATACTTCCTTAGAGGTATGGAAACCATACTCCAGCATCAAGCAACTTGCTGGCGAAATTTCGTTTCAATACTTCCTTAGAGGTATGGAAACATCCATATCAACGTTGCATATTCTCGTTGATAAAAAGTTTCAATACTTCCTTAGAGGTATGGAAACGCGACAAGCCCACGTTCAGGCACGAGGTGTTCCCTGAGTTTCAATACTTCCTTAGAGGTATGGAAACAAGTTTTACCTTTTCTCAGACAACTTCAACTGGAAAAGTTTCAATACTTCCTTAGAGGTATGGAAACTCGATTATTTCTTTTACAAAGACATGCGATCATACAAGTTTCAATACTTCCTTAGAGGTATGGAAACTATACGTTGTAGAAATCGCAAAGGTGGTGATGTTAGTTTCAATACTTCCTTAGAGGTATGGAAACTCTCGAATCCGATATAATCATATTTCCTTATTATATGTTTCAATACTTCCTTAGAGGTATGGAAACCCGCATCTCGTAGGTATTGCTTGCCTTCTGTTCCCTTGTTTCAATACTTCCTTAGAGGTATGGAAACTAAACTTGTAAATCCTTTTGAAGACTTAGAACAACGTTTCAATACTTCCTTAGAGGTATGGAAACGAAACGCCCGCAAACGCTCATCACAAGCCCGTTTCCGTTTCAATACTTCCTTAGAGGTATGGAAACTTGAGTATAAAATCTTCTTCTGATAATGACAAAACAGTTTCAATACTTCCTTAGAGGTATGGAAACTGCTTCTATTACTCTTTGTAGCACGTTCGTGAACTCAGTTTCAATACTTCCTTAGAGGTATGGAAACTCGATAATCTCAGATGCCTCGCCTCAATTTCAATTGGTTTCAATACTTCCTTAGAGGTATGGAAACCTCCACAATGAAAAGAATAGATGGTAAGGTGTGCTTGTTTCAATACTTCCTTAGAGGTATGGAAACCTACTATCTTCTATATATATATTTTTGTTTTTGTTTTGTTTCAATACTTCCTTAGAGGTATGGAAACCTATTTCCCTCTGCCGTCTCTTCGAAATGATCACCTCTGTTTCAATACTTCCTTAGAGGTATGGAAACTGTGAAGGCGTATGAGGTGGAGGATATTCCTGCAATTGGTTTCAATAATTCCTTAGAGGTATGGAAACTTTTTCCAGCATCTTCTTCACGAAGTACGTCTTCATCGTTTCAATAATTCCTTAGAGGTATGGAAACGCGATGTTGCGAGAACGATGAAAGATTTGTATGAACGTTTCAATAATTCCTTAGAGGTATGGAAACTTGTCGAACTCTTTGGTACTTCCATCCGGATACATCTGTTTCAATAATTCCTTAGAGGTATGGAAACGAGTAGTACAGAGGAGAGAGATGCAGATATCCACGACGTTTCAATAATTCCTTAGAGGTATGGAAACCTCGATCGCTTGTGGTATCTCTGTCTGTGCGAGCTGTTTCAATAATTCCTTAGAGGTATGGAAACTTGTGATGATGTCGCCAAGCTTTAGGGGGACATCTGTTTGTTTCAATAATTCCTTAGAGGTATGGAAACCTGATCTAGCCGTCCGGCCAGTCACAGGTTGAGATAGTTTCAATAATTCCTTAGAGGTATGGAAACATGTATTGCAAGGAAAAGCAAAAATAAGATTCGACAGGTTTCAATAATTCCTTAGAGGTATGGAAACTCGAACTCGAAGAGGCCTATGCACCTGTCCAGCCTATGTTTCAATAATTCCTTAGAGGTATGGAAACATCCTCCTTACTTTGGCCGACACCGTTCGTCCGTTTGTTTCAATAATTCCTTAGAGGTATGGAAACCTTCAAGCCATACTAATATTGCGTATTCTCTTCTCAGTTTCAATAATTCCTTAGAGGTATGGAAACAAAAGCCTACGAAGGGCTTCGAGTACCACCAGCTTTTGTTTCAATAATTCCTTAGAGGTATGGAAACGGGCTGAAAAATTTCCCATTTCGTTTTATCACCTCCTGTTTCAATAATTCCTTAGAGGTATGGAAACCAAGGGGAGGATGATACTGAATGGATAGGGGAACTCAGTTTCAATAGTTCCTTAGAGGTATGGAAACACCATTCATCCATTACAACCTCTTTGCCTCTAATTTGTTTCAATAGTTCCTTAGAGGTATGGAAACTGATGTCTTCCCATTGTTTCGTGTTGTCAAACACCTGTTTCAATACTTCCTTAGAGGTATGGAAACTAAAGCATACGCTCCAAAACGTGAACAAATTCTCTCAGTTTCAATAATTCCTTAGAGGTATGGAAACAGTTGGACGACGATCTTGTATTCATAAATGTTGTTGTTTCAATACTTCCTTAGAGGTATGGAAACTAAGACATTCTTTCGCTAAGAAAATCTAATAGTTTGTTTCAATACTTCCTTAGATGTACGAAAAA

>NC_021214|1|1|412-3040|PILER-CR
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCTGTGATCTGTTAACGGGGACATCCACACCCAAAATC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ACTGTCGGAGATGTTCTGCTGTGCATCGTCGAGAGTTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATATAAGCCTTTTCCAGTCTTCGGGGGACATTTCCCA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATGCGAGCACTGTCCTCTCCAACATCCATATACACCG
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CATACTCCAGCATCAAGCAACTTGCTGGCGAAATTTC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATCCATATCAACGTTGCATATTCTCGTTGATAAAAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	GCGACAAGCCCACGTTCAGGCACGAGGTGTTCCCTGA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	AAGTTTTACCTTTTCTCAGACAACTTCAACTGGAAAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCGATTATTTCTTTTACAAAGACATGCGATCATACAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TATACGTTGTAGAAATCGCAAAGGTGGTGATGTTA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCTCGAATCCGATATAATCATATTTCCTTATTATAT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CCGCATCTCGTAGGTATTGCTTGCCTTCTGTTCCCTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TAAACTTGTAAATCCTTTTGAAGACTTAGAACAAC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	GAAACGCCCGCAAACGCTCATCACAAGCCCGTTTCC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TTGAGTATAAAATCTTCTTCTGATAATGACAAAACA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TGCTTCTATTACTCTTTGTAGCACGTTCGTGAACTCA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCGATAATCTCAGATGCCTCGCCTCAATTTCAATTG
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CTCCACAATGAAAAGAATAGATGGTAAGGTGTGCTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CTACTATCTTCTATATATATATTTTTGTTTTTGTTTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CTATTTCCCTCTGCCGTCTCTTCGAAATGATCACCTCT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TGTGAAGGCGTATGAGGTGGAGGATATTCCTGCAATTG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TTTTTCCAGCATCTTCTTCACGAAGTACGTCTTCATC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GCGATGTTGCGAGAACGATGAAAGATTTGTATGAAC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TTGTCGAACTCTTTGGTACTTCCATCCGGATACATCT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GAGTAGTACAGAGGAGAGAGATGCAGATATCCACGAC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CTCGATCGCTTGTGGTATCTCTGTCTGTGCGAGCT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TTGTGATGATGTCGCCAAGCTTTAGGGGGACATCTGTTT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CTGATCTAGCCGTCCGGCCAGTCACAGGTTGAGATA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ATGTATTGCAAGGAAAAGCAAAAATAAGATTCGACAG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TCGAACTCGAAGAGGCCTATGCACCTGTCCAGCCTAT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ATCCTCCTTACTTTGGCCGACACCGTTCGTCCGTTT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CTTCAAGCCATACTAATATTGCGTATTCTCTTCTCA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AAAAGCCTACGAAGGGCTTCGAGTACCACCAGCTTTT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GGGCTGAAAAATTTCCCATTTCGTTTTATCACCTCCT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CAAGGGGAGGATGATACTGAATGGATAGGGGAACTCA
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	ACCATTCATCCATTACAACCTCTTTGCCTCTAATTT
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	TGATGTCTTCCCATTGTTTCGTGTTGTCAAACACCT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TAAAGCATACGCTCCAAAACGTGAACAAATTCTCTCA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGTTGGACGACGATCTTGTATTCATAAATGTTGTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC

>NC_021214|1|1|412-3105|CRISPRCasFinder
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCTGTGATCTGTTAACGGGGACATCCACACCCAAAATC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ACTGTCGGAGATGTTCTGCTGTGCATCGTCGAGAGTTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATATAAGCCTTTTCCAGTCTTCGGGGGACATTTCCCA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATGCGAGCACTGTCCTCTCCAACATCCATATACACCG
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CATACTCCAGCATCAAGCAACTTGCTGGCGAAATTTC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATCCATATCAACGTTGCATATTCTCGTTGATAAAAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	GCGACAAGCCCACGTTCAGGCACGAGGTGTTCCCTGA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	AAGTTTTACCTTTTCTCAGACAACTTCAACTGGAAAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCGATTATTTCTTTTACAAAGACATGCGATCATACAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TATACGTTGTAGAAATCGCAAAGGTGGTGATGTTA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCTCGAATCCGATATAATCATATTTCCTTATTATAT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CCGCATCTCGTAGGTATTGCTTGCCTTCTGTTCCCTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TAAACTTGTAAATCCTTTTGAAGACTTAGAACAAC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	GAAACGCCCGCAAACGCTCATCACAAGCCCGTTTCC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TTGAGTATAAAATCTTCTTCTGATAATGACAAAACA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TGCTTCTATTACTCTTTGTAGCACGTTCGTGAACTCA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCGATAATCTCAGATGCCTCGCCTCAATTTCAATTG
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CTCCACAATGAAAAGAATAGATGGTAAGGTGTGCTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CTACTATCTTCTATATATATATTTTTGTTTTTGTTTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CTATTTCCCTCTGCCGTCTCTTCGAAATGATCACCTCT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TGTGAAGGCGTATGAGGTGGAGGATATTCCTGCAATTG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TTTTTCCAGCATCTTCTTCACGAAGTACGTCTTCATC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GCGATGTTGCGAGAACGATGAAAGATTTGTATGAAC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TTGTCGAACTCTTTGGTACTTCCATCCGGATACATCT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GAGTAGTACAGAGGAGAGAGATGCAGATATCCACGAC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CTCGATCGCTTGTGGTATCTCTGTCTGTGCGAGCT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TTGTGATGATGTCGCCAAGCTTTAGGGGGACATCTGTTT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CTGATCTAGCCGTCCGGCCAGTCACAGGTTGAGATA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ATGTATTGCAAGGAAAAGCAAAAATAAGATTCGACAG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TCGAACTCGAAGAGGCCTATGCACCTGTCCAGCCTAT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ATCCTCCTTACTTTGGCCGACACCGTTCGTCCGTTT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CTTCAAGCCATACTAATATTGCGTATTCTCTTCTCA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AAAAGCCTACGAAGGGCTTCGAGTACCACCAGCTTTT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GGGCTGAAAAATTTCCCATTTCGTTTTATCACCTCCT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CAAGGGGAGGATGATACTGAATGGATAGGGGAACTCA
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	ACCATTCATCCATTACAACCTCTTTGCCTCTAATTT
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	TGATGTCTTCCCATTGTTTCGTGTTGTCAAACACCT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TAAAGCATACGCTCCAAAACGTGAACAAATTCTCTCA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGTTGGACGACGATCTTGTATTCATAAATGTTGTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TAAGACATTCTTTCGCTAAGAAAATCTAATAGTTT
GTTTCAATACTTCCTTAGATGTACGAAAAA

>NC_021214|1|1|412-3105|CRT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCTGTGATCTGTTAACGGGGACATCCACACCCAAAATC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ACTGTCGGAGATGTTCTGCTGTGCATCGTCGAGAGTTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATATAAGCCTTTTCCAGTCTTCGGGGGACATTTCCCA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATGCGAGCACTGTCCTCTCCAACATCCATATACACCG
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CATACTCCAGCATCAAGCAACTTGCTGGCGAAATTTC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATCCATATCAACGTTGCATATTCTCGTTGATAAAAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	GCGACAAGCCCACGTTCAGGCACGAGGTGTTCCCTGA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	AAGTTTTACCTTTTCTCAGACAACTTCAACTGGAAAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCGATTATTTCTTTTACAAAGACATGCGATCATACAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TATACGTTGTAGAAATCGCAAAGGTGGTGATGTTA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCTCGAATCCGATATAATCATATTTCCTTATTATAT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CCGCATCTCGTAGGTATTGCTTGCCTTCTGTTCCCTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TAAACTTGTAAATCCTTTTGAAGACTTAGAACAAC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	GAAACGCCCGCAAACGCTCATCACAAGCCCGTTTCC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TTGAGTATAAAATCTTCTTCTGATAATGACAAAACA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TGCTTCTATTACTCTTTGTAGCACGTTCGTGAACTCA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCGATAATCTCAGATGCCTCGCCTCAATTTCAATTG
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CTCCACAATGAAAAGAATAGATGGTAAGGTGTGCTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CTACTATCTTCTATATATATATTTTTGTTTTTGTTTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CTATTTCCCTCTGCCGTCTCTTCGAAATGATCACCTCT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TGTGAAGGCGTATGAGGTGGAGGATATTCCTGCAATTG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TTTTTCCAGCATCTTCTTCACGAAGTACGTCTTCATC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GCGATGTTGCGAGAACGATGAAAGATTTGTATGAAC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TTGTCGAACTCTTTGGTACTTCCATCCGGATACATCT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GAGTAGTACAGAGGAGAGAGATGCAGATATCCACGAC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CTCGATCGCTTGTGGTATCTCTGTCTGTGCGAGCT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TTGTGATGATGTCGCCAAGCTTTAGGGGGACATCTGTTT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CTGATCTAGCCGTCCGGCCAGTCACAGGTTGAGATA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ATGTATTGCAAGGAAAAGCAAAAATAAGATTCGACAG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TCGAACTCGAAGAGGCCTATGCACCTGTCCAGCCTAT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ATCCTCCTTACTTTGGCCGACACCGTTCGTCCGTTT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CTTCAAGCCATACTAATATTGCGTATTCTCTTCTCA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AAAAGCCTACGAAGGGCTTCGAGTACCACCAGCTTTT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GGGCTGAAAAATTTCCCATTTCGTTTTATCACCTCCT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CAAGGGGAGGATGATACTGAATGGATAGGGGAACTCA
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	ACCATTCATCCATTACAACCTCTTTGCCTCTAATTT
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	TGATGTCTTCCCATTGTTTCGTGTTGTCAAACACCT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TAAAGCATACGCTCCAAAACGTGAACAAATTCTCTCA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGTTGGACGACGATCTTGTATTCATAAATGTTGTT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TAAGACATTCTTTCGCTAAGAAAATCTAATAGTTT
GTTTCAATACTTCCTTAGATGTACGAAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021214.1|WP_004082449.1|10854_11343_-|NAD(P)H-dependent-oxidoreductase-subunit-E	unknown	unknown	gnl|CDD|224817
NC_021214.1|WP_004082448.1|10471_10852_-|hypothetical-protein	unknown	unknown	gnl|CDD|225945
NC_021214.1|WP_004082446.1|8204_8633_-|DUF2202-domain-containing-protein	unknown	unknown	gnl|CDD|224548
NC_021214.1|WP_004082451.1|11546_12308_+|FprA-family-A-type-flavoprotein	unknown	unknown	gnl|CDD|223503
NC_021214.1|WP_004082453.1|12317_13154_+|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|214599
NC_021214.1|WP_010865024.1|3154_5107_-|IGHMBP2-family-helicase	unknown	unknown	gnl|CDD|273041
NC_021214.1|WP_004082444.1|6144_7461_-|transglutaminase-domain-containing-protein	unknown	unknown	gnl|CDD|376628
NC_021214.1|WP_004082436.1|5103_6141_-|dipeptide-epimerase	unknown	unknown	gnl|CDD|239435
NC_021214.1|WP_004082447.1|8629_10453_-|NADH-quinone-oxidoreductase-subunit-NuoF	unknown	unknown	gnl|CDD|224806
NC_021214.1|WP_004082445.1|7494_8169_+|cyclase-family-protein	unknown	unknown	gnl|CDD|224790

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021214.1|WP_004082449.1|10854_11343_-|NAD(P)H-dependent-oxidoreductase-subunit-E	gnl|CDD|224817	COG1905, NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit [Energy production and conversion].	1.62385e-76
NC_021214.1|WP_004082448.1|10471_10852_-|hypothetical-protein	gnl|CDD|225945	COG3411, COG3411, Ferredoxin [Energy production and conversion].	2.20196e-22
NC_021214.1|WP_004082446.1|8204_8633_-|DUF2202-domain-containing-protein	gnl|CDD|224548	COG1633, COG1633, Uncharacterized conserved protein [Function unknown].	3.86933e-25
NC_021214.1|WP_004082451.1|11546_12308_+|FprA-family-A-type-flavoprotein	gnl|CDD|223503	COG0426, FpaA, Uncharacterized flavoproteins [Energy production and conversion].	3.11873e-78
NC_021214.1|WP_004082453.1|12317_13154_+|methyl-accepting-chemotaxis-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	3.55417e-51
NC_021214.1|WP_010865024.1|3154_5107_-|IGHMBP2-family-helicase	gnl|CDD|273041	TIGR00376, DNA-binding_protein_SMUBP-2, DNA helicase, putative. The gene product may represent a DNA helicase. Eukaryotic members of this family have been characterized as binding certain single-stranded G-rich DNA sequences (GGGGT and GGGCT). A number of related proteins are characterized as helicases. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_021214.1|WP_004082444.1|6144_7461_-|transglutaminase-domain-containing-protein	gnl|CDD|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	6.49422e-25
NC_021214.1|WP_004082436.1|5103_6141_-|dipeptide-epimerase	gnl|CDD|239435	cd03319, L-Ala-DL-Glu_epimerase, L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of the murein peptide of peptidoglycan, of which L-Ala-D-Glu is a component. L-Ala-D/L-Glu epimerase is a member of the enolase-superfamily, which is characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	1.01913e-126
NC_021214.1|WP_004082447.1|8629_10453_-|NADH-quinone-oxidoreductase-subunit-NuoF	gnl|CDD|224806	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion].	0
NC_021214.1|WP_004082445.1|7494_8169_+|cyclase-family-protein	gnl|CDD|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	3.2433e-73

Protein sequences

>NC_021214.1|WP_010865024.1|3154_5107_-|IGHMBP2-family-helicase
MTVQQFIKKLVRLVELERNAEINAMLDEMKRLSGEEREKKGRAVLGLTGKFIGEELGYFLVRFGRRKKIDTEIGVGDLVLISKGNPLKSDYTGTVVEKGERFITVAVDRLPSWKLKNVRIDLFASDITFRRQIENLMTLSSEGKKALEFLLGKRKPEESFEEEFTPFDEGLNESQREAVSLALGSSDFFLIHGPFGTGKTRTLVEYIRQEVARGKKILVTAESNLAVDNLVERLWGKVSLVRIGHPSRVSSHLKESTLAHQIETSSEYEKVKKMKEELAKLIKKRDSFTKPSPQWRRGLSDKKILEYAEKNWSARGVSKEKIKEMAEWIKLNSQIQDIRDLIERKEEIIASRIVREAQVVLSTNSSAALEILSGIVFDVVVVDEASQATIPSILIPISKGKKFVLAGDHKQLPPTILSEDAKDLSRTLFEELITRYPEKSSLLDTQYRMNELLMEFPSEEFYDGKLKAAEKVRNITLFDLGVEIPNFGKFWDVVLSPKNVLVFIDTKNRSDRFERQRKDSPSRENPLEAQIVKEVVEKLLSMGVKEDWIGIITPYDDQVNLIRELIEAKVEVHSVDGFQGREKEVIIISFVRSNKNGEIGFLEDLRRLNVSLTRAKRKLIATGDSSTLSVHPTYRRFVEFVKKKGTYVIF
>NC_021214.1|WP_004082436.1|5103_6141_-|dipeptide-epimerase
MSRIVNVKLSLKRYEYEKPFHITGSVSSESRNVEVEIVLESGVKGYGEASPSFRVNGERVEALLAIENAVREMITGIDVRNYARIFEITDRLFGFPSLKAAVQFATLDALSQELGTQVCYLLGGKRDEIETDKTVGIDTVENRVKEAKKIFEEGFRVIKIKVGENLKEDIEAVEEIAKVTRGAKYIVDANMGYTQKEAVEFARAVYQKGIDIAVYEQPVRREDIEGLKFVRFHSPFPVAADESARTKFDVMRLVKEEAVDYVNIKLMKSGISDALAIVEIAESSGLKLMIGCMGESSLGINQSVHFALGTGAFEFHDLDSHLMLKEEVFRGKFIQDGPRMRVKDQ
>NC_021214.1|WP_004082444.1|6144_7461_-|transglutaminase-domain-containing-protein
MEFLIYSLPEEVLREEMLGNFSVALKLIDDFLKKDLPLLQRERLIYEKERIERLLEDYPFTEKEAMEKMREMFEGFSEGEFQYLMNEGVLDYIVVEGEKRFERRFFHNLAFVRSEYRERLRKDERSEKARRILHERLERLIKGEDPKRYRIRARITLKLKETSSKHRVWLPFPKESLQIESVKLLRTSHKSYYISPNDVPQRTIYFEGEDSTFFVEFEYIVREWVNHVDPERVSEKVAGFEEFLKEEPPHIVFTPKLRWLTQTVVGSEVNPYLKAKRIYDWITLNVRYSYVKPYALYENITDFVVNNLKGDCGFQALLFITMCRIAGVPARWQSGWYINPIFGSPHDWALFYVEPYGWLPADLSFGGARRDNESFRSFYFGNLDGFRMVANDGFMKDFDPKTRFVRSDPTDNQVGEAESEEKRLPFESTIEVISFEEV
>NC_021214.1|WP_004082445.1|7494_8169_+|cyclase-family-protein
MFIELSYPIEERMLTYPDNPPDYFEPKSRIEQGDAANTMMIHHFSHTGTHVDAPYHFCEEGWTLDQIPLEYFIFEKPLLVDREKKPMELFTIEDIEELDLNGVDLLMFRSGFAKLRRTDPATYRYMFPGISKELARFLRESVLSLKAVMLDFLSADPIVLGEKENYPAHRWLLSKKFSSKRPIIIFEDVNLEPVAGKKIKRVIALPLRFKGLDGGPVSVLAEVE
>NC_021214.1|WP_004082446.1|8204_8633_-|DUF2202-domain-containing-protein
MIGPRDLLNIALRIESTGYSYYKNLTEKTEGETKALFERLAEQERDHSRKFKEILEKYEQDLNPSDEVLGYLEALAEISIFPKLEETPPDDLREAVRRAIEVEKDSIVFYSEILSYVPEKEPVQTIIDEEKKHLRDLLRLEV
>NC_021214.1|WP_004082447.1|8629_10453_-|NADH-quinone-oxidoreductase-subunit-NuoF
MPLTTNTILICAGGACISAGEKSVKDAFEEELRKYGLDEVVRVIETGCMGACTLGPIAVIYPESVFYQKLTPDAAREIVEEHILKGRIVEKYLYKASEGKPVPRVHEEVPFFKKQVRIVTRNLGVIDPTKIEEYIARDGYFALAKALQMKPEDVIKEIKDSGLRGRGGAGFPTGLKWELAARQKAEKKFVVCNADEGDPGAFMDRSVLEGDPHAVIEGMAIAAYAIGAQKGFVYVRAEYPLAIERLNIALNQAREYGFLGGNIMGTDFSFDIEIRIGAGAFVCGEETALMASIEGERGQPKVKPPYPVEKGLWGYPTVINNVETLANVPWIIRNGAKEFRKYGTENSPGTKVFALAGKVKNTGLVEVPMGITLRELIYEIGGGIAGDKKLKAIQTGGPSGGCIPAEYVDTPVDFESLQKLGAIMGSGGMIVMDEDDCMVDVARFFLEFTVEESCGKCTPCREGTKKMLEILEKITSGEGTEEDIEELEKLAHVVKDTSLCGLGQTAPNPVLSTLRYFRDEYLAHVKEKRCPSKKCKALISYVIDPEKCVGCTACARVCPVQCISGQVRQPHVIDQAECVRCGSCIEVCRFGAISKVTPALPVEEAVE
>NC_021214.1|WP_004082448.1|10471_10852_-|hypothetical-protein
MAKVKSLEELMKIKEQALKDLQLRGETGKRGKITVAMGTCGIAAGAKETLKAIVEALNEYNINDIAVVQSGCMGLCEVEPTVEVRLEGQEPVIYGRVTPENAKRIVKMHILEGRVVEDLVVKRGEA
>NC_021214.1|WP_004082449.1|10854_11343_-|NAD(P)H-dependent-oxidoreductase-subunit-E
MVKSKEELFKELENFIEENGYEGKKDALIQVLHKAQELFGYLPADVLEYISDKLDVPLSKVYGVVTFYNFFSTKPKGKHQIKVCLGTACYVKGADRIFERFLEELKVNPDEPTSDGMFSVHGVRCLGACSMAPVVMVDEDDFYGRVTPDMVPQIISKYKREG
>NC_021214.1|WP_004082451.1|11546_12308_+|FprA-family-A-type-flavoprotein
MFENEILFDNGQHKFMFLGWEEKEEEIVQTNQYLILDGNEGILLDPGGAHVFPRVMSNVAEVVDLSSIRHIFYTHQDPDVTSGILLWLSICENAKIYISSLWVRFLPHFGIYDQKRIVPISDKGTKIKLLSGNELEILPAHFLHSTGNFVLYDPVAKILFSGDIGAAVFEKGKRYRYVDDFERHLPLMEAFHKRYMSSNAACKKWVDMVSKKKIDMIAPQHGAVFRGESVKKFLEWFRNLKCGVDLIDNLYSL
>NC_021214.1|WP_004082453.1|12317_13154_+|methyl-accepting-chemotaxis-protein
MREREIVDKLTSAFFAENTIISFTSQLDEALTRKLRRMQRRIEEVKERFVNLNRLFQELVGDFQAKSDQLVSVIQDMEKISENIMEELKKSGTNVDQIVERVKEASSQIGETLENIRSIEKLIQNIMRIARETNILALNATIEAARAGEAGKGFMIVANEVQNLSNETNEVTKQIVEKAREILESSQRSLENLEFMANLFETVGKTLQNMVRFMENNVKLLQEVRNSLDTSKESLSEKSAEIDSATKVLEETAGGFTTINRVINSVITAQRKLKDLKI

Crispr_ID: NC_021214_2

• CRISPR_ID: NC_021214_2
• CRISPR_location: 369173-369734
• CRISPR_type: Orphan
• Repeat_type: III-A
• Spacer_info: 8 spacers

Consensus repeat of NC_021214_2

Consensus_repeat	Method
GTTTCAATAATTCCTTAGAGGTATGGAAAC	PILER-CR
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CRISPRCasFinder
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CRT

spacers of NC_021214_2

>2.1|369203|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
AGACAATCGTGGATCAGGTCATCAATGCCCTGAATTA
>2.2|369270|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ACTTGTGGAGATTGAGGAACATCTAGGAAAGAACATC
>2.3|369337|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
AGCGATAACATTCAATCCTTCGACGAGGTACACCAA
>2.4|369403|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TAATCTTGTCTGTAGGATCCTCTGAAAACCCTCTCTG
>2.5|369470|39|NC_021214|PILER-CR,CRISPRCasFinder,CRT
GTGGAAGAGTCCGCAGGAAAAGACAGCGCTGGGTAGGTA
>2.6|369539|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TAGGTGTCTGAAACCGAGTCAATCAGTGCATTGTCGA
>2.7|369606|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CAGGAGAGCCATTTTCTGAGTATTTCGCAAGGAAGAT
>2.8|369673|32|NC_021214|CRISPRCasFinder,CRT
AGTGATCCTCGTGAATTGTGCTCCTTTTGATC

CRISPR arrays and Neighbor proteins around NC_021214_2

CRISPR arrays

The CRISPR arrays of NC_021214_2

>merge|NC_021214|2|369173-369734|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATAATTCCTTAGAGGTATGGAAACAGACAATCGTGGATCAGGTCATCAATGCCCTGAATTAGTTTCAATAATTCCTTAGAGGTATGGAAACACTTGTGGAGATTGAGGAACATCTAGGAAAGAACATCGTTTCAATAATTCCTTAGAGGTATGGAAACAGCGATAACATTCAATCCTTCGACGAGGTACACCAAGTTTCAATAATTCCTTAGAGGTATGGAAACTAATCTTGTCTGTAGGATCCTCTGAAAACCCTCTCTGGTTTCAATAATTCCTTAGAGGTATGGAAACGTGGAAGAGTCCGCAGGAAAAGACAGCGCTGGGTAGGTAGTTTCAATAATTCCTTAGAGGTATGGAAACTAGGTGTCTGAAACCGAGTCAATCAGTGCATTGTCGAGTTTCAATAATTCCTTAGAGGTATGGAAACCAGGAGAGCCATTTTCTGAGTATTTCGCAAGGAAGATGTTTCAATAATTCCTTAGAGGTATGGAAACAGTGATCCTCGTGAATTGTGCTCCTTTTGATCGTCTCAATGCATCCTTAGAGGCACAGAAAT

>NC_021214|2|2|369173-369672|PILER-CR
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGACAATCGTGGATCAGGTCATCAATGCCCTGAATTA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ACTTGTGGAGATTGAGGAACATCTAGGAAAGAACATC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGCGATAACATTCAATCCTTCGACGAGGTACACCAA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TAATCTTGTCTGTAGGATCCTCTGAAAACCCTCTCTG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GTGGAAGAGTCCGCAGGAAAAGACAGCGCTGGGTAGGTA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TAGGTGTCTGAAACCGAGTCAATCAGTGCATTGTCGA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CAGGAGAGCCATTTTCTGAGTATTTCGCAAGGAAGAT
GTTTCAATAATTCCTTAGAGGTATGGAAAC

>NC_021214|2|2|369173-369734|CRISPRCasFinder
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGACAATCGTGGATCAGGTCATCAATGCCCTGAATTA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ACTTGTGGAGATTGAGGAACATCTAGGAAAGAACATC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGCGATAACATTCAATCCTTCGACGAGGTACACCAA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TAATCTTGTCTGTAGGATCCTCTGAAAACCCTCTCTG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GTGGAAGAGTCCGCAGGAAAAGACAGCGCTGGGTAGGTA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TAGGTGTCTGAAACCGAGTCAATCAGTGCATTGTCGA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CAGGAGAGCCATTTTCTGAGTATTTCGCAAGGAAGAT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGTGATCCTCGTGAATTGTGCTCCTTTTGATC
GTCTCAATGCATCCTTAGAGGCACAGAAAT

>NC_021214|2|2|369173-369734|CRT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGACAATCGTGGATCAGGTCATCAATGCCCTGAATTA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ACTTGTGGAGATTGAGGAACATCTAGGAAAGAACATC
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGCGATAACATTCAATCCTTCGACGAGGTACACCAA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TAATCTTGTCTGTAGGATCCTCTGAAAACCCTCTCTG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GTGGAAGAGTCCGCAGGAAAAGACAGCGCTGGGTAGGTA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TAGGTGTCTGAAACCGAGTCAATCAGTGCATTGTCGA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CAGGAGAGCCATTTTCTGAGTATTTCGCAAGGAAGAT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	AGTGATCCTCGTGAATTGTGCTCCTTTTGATC
GTCTCAATGCATCCTTAGAGGCACAGAAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021214.1|WP_004083125.1|361175_362192_+|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl|CDD|181535
NC_021214.1|WP_004083141.1|369844_371059_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|182528
NC_021214.1|WP_004083154.1|374028_375015_-|TolC-family-protein	unknown	unknown	gnl|CDD|224455
NC_021214.1|WP_004083132.1|364208_364970_+|shikimate-dehydrogenase	unknown	unknown	gnl|CDD|223247
NC_021214.1|WP_004083135.1|366044_367523_+|bifunctional-shikimate-kinase-AroK/3-dehydroquinate-synthase-AroB	unknown	unknown	gnl|CDD|172457
NC_021214.1|WP_004083156.1|375182_376388_+|threonine-ammonia-lyase	unknown	unknown	gnl|CDD|236182
NC_021214.1|WP_004083139.1|367946_368549_-|LysE-family-translocator	unknown	unknown	gnl|CDD|280058
NC_021214.1|WP_004083161.1|378792_379143_+|nucleotide-pyrophosphohydrolase	unknown	unknown	gnl|CDD|212135
NC_021214.1|WP_004083137.1|367519_367954_+|type-II-3-dehydroquinate-dehydratase	unknown	unknown	gnl|CDD|235443
NC_021214.1|WP_004083147.1|372750_374013_-|TolC-family-protein	unknown	unknown	gnl|CDD|224455
NC_021214.1|WP_004083122.1|359677_360919_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_021214.1|WP_004083158.1|376403_376610_+|hypothetical-protein	unknown	unknown	unknown
NC_021214.1|WP_004083127.1|362188_362950_+|prephenate-dehydrogenase	unknown	unknown	gnl|CDD|223364
NC_021214.1|WP_004083133.1|364966_366097_+|chorismate-synthase	unknown	unknown	gnl|CDD|272865
NC_021214.1|WP_004083129.1|362946_364212_+|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|235037
NC_021214.1|WP_004083108.1|359488_359665_+|hypothetical-protein	unknown	unknown	unknown
NC_021214.1|WP_015646094.1|376612_377521_+|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl|CDD|224513
NC_021214.1|WP_004083160.1|377534_378605_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NC_021214.1|WP_004083145.1|371746_372754_-|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NC_021214.1|WP_004083143.1|371045_371750_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021214.1|WP_004083125.1|361175_362192_+|3-deoxy-7-phosphoheptulonate-synthase	gnl|CDD|181535	PRK08673, PRK08673, 3-deoxy-7-phosphoheptulonate synthase; Reviewed.	0
NC_021214.1|WP_004083141.1|369844_371059_-|ABC-transporter-permease	gnl|CDD|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	3.39326e-53
NC_021214.1|WP_004083132.1|364208_364970_+|shikimate-dehydrogenase	gnl|CDD|223247	COG0169, AroE, Shikimate 5-dehydrogenase [Amino acid transport and metabolism].	8.72506e-87
NC_021214.1|WP_004083135.1|366044_367523_+|bifunctional-shikimate-kinase-AroK/3-dehydroquinate-synthase-AroB	gnl|CDD|172457	PRK13951, PRK13951, bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB.	0
NC_021214.1|WP_004083156.1|375182_376388_+|threonine-ammonia-lyase	gnl|CDD|236182	PRK08198, PRK08198, threonine dehydratase; Provisional.	0
NC_021214.1|WP_004083139.1|367946_368549_-|LysE-family-translocator	gnl|CDD|280058	pfam01810, LysE, LysE type translocator. This family consists of various hypothetical proteins and an l-lysine exporter LysE from Corynebacterium glutamicum which is proposed to be the first of a novel family of translocators. LysE exports l-lysine from the cell into the surrounding medium and is predicted to span the membrane six times. The physiological function of the exporter is to excrete excess l-Lysine as a result of natural flux imbalances or peptide hydrolysis; and also after artificial deregulation of l-Lysine biosynthesis as used by the biotechnology. industry for the production of l-lysine.	6.3777e-39
NC_021214.1|WP_004083161.1|378792_379143_+|nucleotide-pyrophosphohydrolase	gnl|CDD|212135	cd11528, NTP-PPase_MazG_Nterm, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs. MazG is a NTP-PPase that hydrolyzes all canonical NTPs into their corresponding nucleoside monophosphates and pyrophosphate. The prototype of this family is MazG proteins from Escherichia coli (EcMazG) that represents the most abundant form consisting two sequence-related domains in tandem, this family corresponding to the N-terminal MazG-like domain. EcMazG functions as a regulator of cellular response to starvation by lowering the cellular concentration of guanosine 3',5'-bispyrophosphate (ppGpp). EcMazG exists as a dimer; each monomer contains two tandem MazG-like domains with similarly folded globular structures. However, only the C-terminal domain has well-ordered active site and exhibits an NTPase activity responsible for the regulation of bacterial cell survival under nutritional stress. Divalent ions, such as Mg2+ or Mn2+, are required for activity; however, this domain does not exhibit an NTPase activity despite containing structural features such as the EEXX(E/D) motif and key basic catalytic residues responsible for nucleotide pyrophosphohydrolysis activity. It is suggested that the N-terminal domain of EcMazG might have a house-cleaning function by hydrolyzing noncanonical NTPs whose incorporation into the nascent DNA leads to increased mutagenesis and DNA damage.	3.00204e-28
NC_021214.1|WP_004083137.1|367519_367954_+|type-II-3-dehydroquinate-dehydratase	gnl|CDD|235443	PRK05395, PRK05395, type II 3-dehydroquinate dehydratase.	1.05728e-86
NC_021214.1|WP_004083147.1|372750_374013_-|TolC-family-protein	gnl|CDD|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	3.16754e-11
NC_021214.1|WP_004083122.1|359677_360919_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.68098e-72
NC_021214.1|WP_004083127.1|362188_362950_+|prephenate-dehydrogenase	gnl|CDD|223364	COG0287, TyrA, Prephenate dehydrogenase [Amino acid transport and metabolism].	9.77158e-66
NC_021214.1|WP_004083133.1|364966_366097_+|chorismate-synthase	gnl|CDD|272865	TIGR00033, Chorismate_synthase, chorismate synthase. Homotetramer (noted in E.coli) suggests reason for good conservation. [Amino acid biosynthesis, Aromatic amino acid family].	0
NC_021214.1|WP_004083129.1|362946_364212_+|3-phosphoshikimate-1-carboxyvinyltransferase	gnl|CDD|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
NC_021214.1|WP_004083154.1|374028_375015_-|TolC-family-protein	gnl|CDD|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	5.81234e-16
NC_021214.1|WP_015646094.1|376612_377521_+|diacylglycerol-kinase-family-lipid-kinase	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	1.23273e-90
NC_021214.1|WP_004083160.1|377534_378605_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.80206e-21
NC_021214.1|WP_004083145.1|371746_372754_-|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	3.97378e-35
NC_021214.1|WP_004083143.1|371045_371750_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	2.80604e-125

Protein sequences

>NC_021214.1|WP_004083139.1|367946_368549_-|LysE-family-translocator
MISIFFGSFLVGLSGAVAPGPLMMIAVYQSAKSWKNSIKLIFGHVVLEAFLVLLLVLGFQWVLKSPLVTKVIGLLGGSFLAFMGVSQLTAIKGEISQVEKTDQKIPLPITGALVSLSNPYFLLWWMSVGSAFLVKAQTSLLAGVTAFYFGHILSDILWYSLIGVFGNTILKSSLIYKIVMTVTGLFLIGFGLFFVLDSLR
>NC_021214.1|WP_004083137.1|367519_367954_+|type-II-3-dehydroquinate-dehydratase
MKVLVVNGPNLNMLGKRDKNIYGNFSHEDLVKMIEDWGRKNGVEVEVFQSNHEGKILDRLHRLDFDGLVINPGAFTHYSYAIRDALEIVKVPKVEVHISNIHRREEFRRRSVTAEVCDGQISGLGVYGYLLALEYIKKKLEELT
>NC_021214.1|WP_004083135.1|366044_367523_+|bifunctional-shikimate-kinase-AroK/3-dehydroquinate-synthase-AroB
MRIFLVGMMGSGKSTIGKRISEVLDLQFIDMDEEIERREGRSVRRIFEEDGEEYFRLKEKELLKELVERDNVVVATGGGVVVDPENRELLKKEKTLFLYAPPEVLMERVTTENRPLLSEGKERIREIWEKRKQFYAEFRRIDTSRLNEWETTALVVLEALDEKEISTIEKPHLVKIILGGFKRVRNEELVFTTERVEKIYGRYLPENRLLFPDGEEVKTLEHVSRAYYELIRMDFPRGKTIAGVGGGALTDFTGFVASTFKRGVGLSFYPTTLLAQVDASVGGKNAIDFAGVKNVVGTFRMPDYVIIDPTVTLSMDEGRFEEGVVEAFKMTILSGRGVELFDEPEKIEKRNLRVLSEMVKISVEEKARIVMEDPYDMGLRHALNLGHTLGHVYEMLEGVPHGIAVAWGIEKETMYLYRKGIVPKETMRWIVEKVKQIVPIPVPSVDVEKARNLILNDKKILKGSRVRLPYVKEIGKIEFLEVDPLELLEVVD
>NC_021214.1|WP_004083133.1|364966_366097_+|chorismate-synthase
MKLTIAGDSHGKYMVAILEGLPSGIRVDEELIRRDLFRRRNCYGRGKRMKMEEDAFEIVSGLWKGITTGAPVTILIPNRAGNPVKDVRSVPRPGHIDYAAWVKYKLPDLNIYVERSSARWTVALTAAGSLLKSLLKEFGIEVLGFVTRLGNVEARDIPGDFEELKRRRDESVVFCPDPEATKEMVAEIDRAKEEGNTLGGKVKVIARGVPAGIGSYSDLFKKLDSKIGSLFFAIPAVKGVVIGSEEMWYGFDYLDEFELEDGKIKRKTNNLGGIEGGITNGEDVWVNVSVKPIPTTGKPLKSVDLRTMEPAKTPYVRSDVTAVPPASVVCEAALAVVISDALLEHLGDGNIDDLKRRFENENLPRWNDGFWKEHYR
>NC_021214.1|WP_004083132.1|364208_364970_+|shikimate-dehydrogenase
MKFCIIGYPVRHSISPRLYNEYFKRAGMNHSYGMEEIPPESFDTEIRRILEEYDGFNATIPHKERVMRYVEPSEDAQRIKAVNCVFRGKGYNTDWVGVVKSLEGVEVKEPVVVVGAGGAARAVIYALLQMGVKDIWVVNRTIERAKALDFPVKIFSLDQLDEVVKKAKSLFNTTSVGMKGEELPVSDDSLKNLSLVYDVIYFDTPLVVKARKLGVKHIIKGNLMFYYQAMENLKIWGIYDEEVFKEVFGEVLK
>NC_021214.1|WP_004083129.1|362946_364212_+|3-phosphoshikimate-1-carboxyvinyltransferase
MKVLPAKKVEGVLSVPPDKSITHRALILSALAETESTLYNLLRCLDTERTHDILEKLGTRFEGDWEKMKVFPKPFAEPIEPLFCGNSGTTTRLMSGVLASYEMFTVLYGDPSLSRRPMRRVIEPLEMMGARFMARQNNYLPMAIKGNHLSGISYKTPVASAQVKSAVLLAGLRASGRTIVIEPAKSRDHTERMLKNLGVPVEVEGTRVVLEPATFRGFTMKVPGDISSAAFFVVLGAIHPNARITVTDVGLNPTRTGLLEVMKLMGANLEWEITEENLEPIGTVRVETSPNLKGVVVPEHLVPLMIDELPLVALLGVFAEGETVVRNAEELRKKESDRIRVLVENFKRLGVEIEEFKDGFKIVGKQSIKGGSVDPEGDHRMAMLFSIAGLVSEEGVDVKDHECVAVSFPNFYELLERVVIS
>NC_021214.1|WP_004083127.1|362188_362950_+|prephenate-dehydrogenase
MKISVLGAGCIGGSIALKLKEKHHVTAFDRDEETMKALEENGIETVSKESDLYDTDLLVLALPMSVEERFLKETDFSGKILDVASVKTPFMEIARERGLNFTGGHPMAGNERKGKSGWDREMFDGKIFFLCSLDGKEDGMIENIVKDLGARPLWIDYRIHDEIVAAVSHVQYLISLSARYVGKPFEEYAGPGYLSNTRLSKQNMEMALDMIRYNKENILKYLENARNFLNVLYHLTEKEDFENLKKVIREVIS
>NC_021214.1|WP_004083125.1|361175_362192_+|3-deoxy-7-phosphoheptulonate-synthase
MIVVLKPGSTEEDIRKVVKLAESYNLKCHISKGQERTVIGIIGDDRYVVADKFESLDCVESVVRVLKPYKLVSREFHPEDTVIDLGDVKIGNGYFTIIAGPCSVEGREMLMETAHFLSELGVKVLRGGAYKPRTSPYSFQGLGEKGLEYLREAADKYGMYVVTEALGEDDLPKVAEYADIIQIGARNAQNFRLLSKAGSYNKPVLLKRGFMNTIEEFLLSAEYIANSGNTKIILCERGIRTFEKATRNTLDISAVPIIRKESHLPILVDPSHSGGRRDLVIPLSRAAIAVGAHGIIVEVHPEPEKALSDGKQSLDFELFKELVQEMKKLADALGVKVN
>NC_021214.1|WP_004083122.1|359677_360919_+|MFS-transporter
MNEILHWKRNFFLLALGRFVSILGSSVQAVAIPLFVLDLTHSGSAVALMTVAYMVPRILFTPIAGIVGDRGDRKFLMVSMDFLRGFLICFLALLAFRNSITLPVLYVSQIAMAIMDNLFDIPTGAMFPDIVPQDFLMRANSIMGMVRIFPQILGPALGGVIYGFYGIAIVFLVNGVSFVLSAISEIFIVYSRKVEKKPAKFSQILEDLKEGFLFIWNHELIRTILIFALFLNLLISPLFMVVYPYTIREVMKFSAQEFGFLETSFTLGALLGNFLIASYLSKKNMWKAMKISIFLFELPIVFLGFLVMPDFSLNRLVLFSLFFITFLIMGFLNPIINVPLDTAFQKMTPSHIRARAFSFLILVANGVTPLGSVLYGYLVDRVPVHFLYYVVGALSFLVAVLLLVALRGKELPT
>NC_021214.1|WP_004083108.1|359488_359665_+|hypothetical-protein
MKVYLMVSTILVVMLFSLIWLYVLFFSTLETVPSSPAVWEPGITETSSTMVPGSLQNR
>NC_021214.1|WP_004083141.1|369844_371059_-|ABC-transporter-permease
MEILKEVLRSLLANKMRTFLSMLGIVIGVTAVIMVMSLGAGMRESVTERLTSLGSNIIMITPGFAGGRGGTIAQSVESLEEDDVEDILKMCPSVDKAIDLMSGSFLVQYRETNTRSNVYSAPPDIFHILNLKVSSGRTFSEEDSAANVAIIGQEVAYNLFGNENPVGKKIYLVQGNRKLVFEIIGIFERTGSILMFNPDNMILIPYETGKFRVFQTHGKVSMILATSKSADVAQRAVMEIDHLLYTKFHEEESYYNIISQQAILNVVSESVSIINLVLVAIAAVSLIVGGIGIMNIMLVSVVERTREIGIKMAIGASRLRILLEFLVESVVITFVAGAIGVALGILGSNTIVNTFGSQYGLKAVVDPFSVIIAFGVSASVGLFFGFYPAYRASRLSPIEALRYE
>NC_021214.1|WP_004083143.1|371045_371750_-|ABC-transporter-ATP-binding-protein
MKKVMELVDVWKIYDLGEVKVEALRGVSFEVFEGEYVIIIGPSGSGKSTLLHILGCLDRPTKGKVLIEGEEVSRMGDRRLAQVRNRKIGFVFQSYNLLPRLTALENVELPMIYAGVPAKERKRRAKELLELVGLGDRLHHRPNQLSGGQQQRVAIARALANDPVFILADEPTGNLDTKTGEEILELFRKLHEMGKTLVVVTHNLEMVDEGTCIVRIRDGRIEGIERRGVVYGDT
>NC_021214.1|WP_004083145.1|371746_372754_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MKKWITLLIIAVLVVLVAVVIFLNRASAQTVSEKDATSTQAPVFLTYTVTKENETVEIVGQVTADTKKVTSKVSGDVLEIYVEEGDVVQVGQKIAKIDDTDYQISYLSALNSYKTSPTEINRLNLEKAKENLENTTVVSPVSGVVQAVNVDVGDRVSVGTSIVTIVETDTLRVEGSISEYDLKNVKEGMKAVFTFEQLGLTLTGKVKRISPVAETSGGVTVIPVEFSFDQTPPSLVIPGLTCDVEIIIKEATSSFFIPKEAVRQDQNGYYVMKQTPQGPQKVYVELGEELNDKIEIKKGVSEGDVLLLIPSQQEIQRLRTRQGLPMFGPGGGRAR
>NC_021214.1|WP_004083147.1|372750_374013_-|TolC-family-protein
MKRFFLVFLLVPVFLAGNVFDLFKENLENSYSYWSSVEKFKEAQLNYKRYTNFWNPEISVSLGKTGITITEDGVSDFSISPIVNFVNIYGFELGLSFPISVNTDDWSFNFEGTQLSVSRGLKTEYTVDRLMAESSYLSSKYSLKSTKNSVFIQTVQDIFDWYYYTKKIEILSQRLQVLNEKLSKAKDDDEKKALEKQILSTEQTLRNAEYKLQTIQTKNIDEEVYQKTRNLLESITLPATTLEYREDLKALELQKKAEEIEKKTWFLPYLPDLTVSFNYDFEDSEWSIGIGFQMTLWDFGERKLEAEKRKSQLVSLEYQEEVKNIENSLNQELVNIANLESQLKQKEIELEDLEESSKTSDQLFNKGFLSEEDYALSKLDYAEGTLEKENMENSLILEKLKYISILGYDLEKFLKEGDQN
>NC_021214.1|WP_004083154.1|374028_375015_-|TolC-family-protein
MKNLLVVLLSLVSVLSFSVSLNDVLQTALASSTDYQIAQISLESATMDYEKAKLEATNKRSELSAELSYYNNLQSYRNSLKSAYQDVLGRIFNLLTADLSYEIAQLNFENAQEDYKTSQELFKKNLISENDLKDSELTLEEASNNLLSAQKDLEEAQKDYEEIFSVEVSEIELPLIDYQNLVGEDEYLDNLSSVKIAELNMKIAEYDLNNLSASASKYEQKKAELNYKKSKMNYDEALKEAKDSYKSTLDSLEIAFLNLKVLKEKIELNENILKDYQERYEKGLISKKELNTQKINLLNIKKNYLNSLRSYYISIVNLLIDAGKEVSF
>NC_021214.1|WP_004083156.1|375182_376388_+|threonine-ammonia-lyase
MITLEDIKEAQRTLKNVVHRTALAYSSVLSEVTGGEIYLKMENLQKTGSFKIRGAYNKIAHLSEEERKRGVVAASAGNHAQGVALAAQIFGIPATIVMPRYAPLSKITKTRNLGAQVILEGNIFDEAYEAALRIQEKTGAVFVHPFNDPHVIAGQGTIGLEIMEDLPDVEVVVVPVGGGGLISGVSVAIKSMNPEVKVIGVQTENMPSMIASLRRGRAERVEGKPTLADGIAVKKPGDLTFELVKKYVDEMVAVNEEEIADAILFLLEQAKVVAEGAGAVGVAAVLNKLDVKGKKVAIVISGGNIDVNMIDRIINKGLVKSGRKVFIETFVMDRPGALKELLGIVAELGANVLSVFHNRSAKEVPIGFAKIELELETVDEKHVEEIERVLIAKGYEVRIVG
>NC_021214.1|WP_004083158.1|376403_376610_+|hypothetical-protein
MRFVSDFLFFAGFGLLFIAIVFFDLGTRAIKKKQNQKKKFYDKKGWQFLSVSLGAFAVSILLALIGRG
>NC_021214.1|WP_015646094.1|376612_377521_+|diacylglycerol-kinase-family-lipid-kinase
MVFLICNPAAGGGRAGKIWNRVEDLLKKHGIDHKFAFTERPGHAMEISKKAFKEGYRRIAAFGGDGTVNEMVNGIFLNGYDLREVVFGWIPFGSGKDWARTIGVPLEIEEAIKMLKDGKEFVQDLGVGEYEKASGEIEKRAFVNVAGLFFDGFVTYRTNLLKRKNRVSYFSRIFSSIIEYDPPTARIQIDEKVWEKRVFSMNVGICKYNGGGMNQLPHAVPDDGLLAVTVINDIGKLRILANLHRVFNGKLLEHPGVEGYQAKKVVVEFQRDEPVEFDGESFWAKKIFFSIIPGVIRVLVKK
>NC_021214.1|WP_004083160.1|377534_378605_-|glycosyltransferase-family-4-protein
MKIGFLSRWGATCGVGMHAEILAREFIRMGHEVVVFAPTEESASKEVKYYKRTEAQDPEFVKREIYTEVDNVTEEGWVKEEEILKENLDLLIIETFWRVPVKPLTRLIEKLKIPVISVFHEANIFKAREVVKLPCDKIVVFDRRFYDEILEFYEIPREKVEVISYPVMKPYDAEPERPVSEDKFLFFSFGRQPVEEYCDFLNALKKLRKRFDNVHYWIIRSDGRVDYEAEWITQWQKRPTVEKLYSYLKGSNVHLLPKGNTPNVVVSSTLYQIIASETPIVIRDSRFVETIETDVYGFGPIVKYRNIHDLVHKLELLMLDRELVEDIKKEVRVFVEKYGGDKIAQEFLDLAKTITK
>NC_021214.1|WP_004083161.1|378792_379143_+|nucleotide-pyrophosphohydrolase
MVERLLEIIERSLRKCPWLEKQSIETLLEALASEIEEVAEAVKKNDLANLEEEIGDLIYDALLVAAVAQRDYGIDLESAIQKVVEKISHRKPWLFWEEKISLEEAEKIWKERKKKI

Crispr_ID: NC_021214_3

• CRISPR_ID: NC_021214_3
• CRISPR_location: 396571-397136
• CRISPR_type: Orphan
• Repeat_type: III-A
• Spacer_info: 8 spacers

Consensus repeat of NC_021214_3

Consensus_repeat	Method
GTTTCAATAATTCCTTAGAGGTATGGAAAC	PILER-CR
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CRISPRCasFinder
GTTTCAATANTTCCTTAGAGGTATGGAAAC	CRT

spacers of NC_021214_3

>3.1|396601|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
GAAGGTTTGATGTAGAAGGTGGTGTGTACTGGAGAA
>3.2|396667|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CCAGAGAAGGAGGAGTGTTTTGGGATTTTGCATGT
>3.3|396732|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TGATCCAGACGGCATTCGTCCTGTACTGAGCTGGAAG
>3.4|396799|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TCAACCTCAAGCACCATTTGCCCGTAGCGCGTTGACA
>3.5|396866|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ACTAGTATGAGCTACTACAATCCAACCACTGCACCTA
>3.6|396933|39|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ACGTGAGCGCGTTTCTTTGCCATTTTCAGTATCGTATTT
>3.7|397002|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ACCTGTGCTAAATTCTCATCCCAGTATCGGATCTCG
>3.8|397068|39|NC_021214|CRISPRCasFinder,CRT
TCTAAACCAGTGATACGACTCAAAAGCAATAACCTCATT

CRISPR arrays and Neighbor proteins around NC_021214_3

CRISPR arrays

The CRISPR arrays of NC_021214_3

>merge|NC_021214|3|396571-397136|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATAATTCCTTAGAGGTATGGAAACGAAGGTTTGATGTAGAAGGTGGTGTGTACTGGAGAAGTTTCAATAATTCCTTAGAGGTATGGAAACCCAGAGAAGGAGGAGTGTTTTGGGATTTTGCATGTGTTTCAATAATTCCTTAGAGGTATGGAAACTGATCCAGACGGCATTCGTCCTGTACTGAGCTGGAAGGTTTCAATAATTCCTTAGAGGTATGGAAACTCAACCTCAAGCACCATTTGCCCGTAGCGCGTTGACAGTTTCAATAATTCCTTAGAGGTATGGAAACACTAGTATGAGCTACTACAATCCAACCACTGCACCTAGTTTCAATAGTTCCTTAGAGGTATGGAAACACGTGAGCGCGTTTCTTTGCCATTTTCAGTATCGTATTTGTTTCAATAGTTCCTTAGAGGTATGGAAACACCTGTGCTAAATTCTCATCCCAGTATCGGATCTCGGTTTCAATAGTTCCTTAGAGGTATGGAAACTCTAAACCAGTGATACGACTCAAAAGCAATAACCTCATTGTTTCAACACTTCCTTATAGGTACAGAAAC

>NC_021214|3|3|396571-397067|PILER-CR
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GAAGGTTTGATGTAGAAGGTGGTGTGTACTGGAGAA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CCAGAGAAGGAGGAGTGTTTTGGGATTTTGCATGT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TGATCCAGACGGCATTCGTCCTGTACTGAGCTGGAAG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TCAACCTCAAGCACCATTTGCCCGTAGCGCGTTGACA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ACTAGTATGAGCTACTACAATCCAACCACTGCACCTA
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	ACGTGAGCGCGTTTCTTTGCCATTTTCAGTATCGTATTT
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	ACCTGTGCTAAATTCTCATCCCAGTATCGGATCTCG
GTTTCAATAGTTCCTTAGAGGTATGGAAAC

>NC_021214|3|3|396571-397136|CRISPRCasFinder
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GAAGGTTTGATGTAGAAGGTGGTGTGTACTGGAGAA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CCAGAGAAGGAGGAGTGTTTTGGGATTTTGCATGT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TGATCCAGACGGCATTCGTCCTGTACTGAGCTGGAAG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TCAACCTCAAGCACCATTTGCCCGTAGCGCGTTGACA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ACTAGTATGAGCTACTACAATCCAACCACTGCACCTA
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	ACGTGAGCGCGTTTCTTTGCCATTTTCAGTATCGTATTT
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	ACCTGTGCTAAATTCTCATCCCAGTATCGGATCTCG
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	TCTAAACCAGTGATACGACTCAAAAGCAATAACCTCATT
GTTTCAACACTTCCTTATAGGTACAGAAAC

>NC_021214|3|3|396571-397136|CRT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GAAGGTTTGATGTAGAAGGTGGTGTGTACTGGAGAA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	CCAGAGAAGGAGGAGTGTTTTGGGATTTTGCATGT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TGATCCAGACGGCATTCGTCCTGTACTGAGCTGGAAG
GTTTCAATAATTCCTTAGAGGTATGGAAAC	TCAACCTCAAGCACCATTTGCCCGTAGCGCGTTGACA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	ACTAGTATGAGCTACTACAATCCAACCACTGCACCTA
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	ACGTGAGCGCGTTTCTTTGCCATTTTCAGTATCGTATTT
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	ACCTGTGCTAAATTCTCATCCCAGTATCGGATCTCG
GTTTCAATAGTTCCTTAGAGGTATGGAAAC	TCTAAACCAGTGATACGACTCAAAAGCAATAACCTCATT
GTTTCAACACTTCCTTATAGGTACAGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021214.1|WP_004083193.1|397245_398211_+|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|223318
NC_021214.1|WP_004083198.1|400055_401405_+|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl|CDD|273568
NC_021214.1|WP_004083185.1|388586_389045_+|arginine-repressor	unknown	unknown	gnl|CDD|130592
NC_021214.1|WP_004083188.1|394077_394521_+|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl|CDD|223149
NC_021214.1|WP_004083177.1|385330_386008_+|TIGR00266-family-protein	unknown	unknown	gnl|CDD|224924
NC_021214.1|WP_004083197.1|399674_400010_+|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|223672
NC_021214.1|WP_004083187.1|392270_394061_+|molecular-chaperone-DnaK	unknown	unknown	gnl|CDD|234715
NC_021214.1|WP_162487497.1|387686_388430_-|KaiC-domain-containing-protein	unknown	unknown	gnl|CDD|235281
NC_021214.1|WP_004083200.1|401381_402044_-|endonuclease-III-domain-containing-protein	unknown	unknown	gnl|CDD|225140
NC_021214.1|WP_004083192.1|395218_395944_-|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NC_021214.1|WP_004083179.1|386127_387237_+|MFS-transporter	unknown	unknown	gnl|CDD|340883
NC_021214.1|WP_004083195.1|398318_399650_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|181958
NC_021214.1|WP_004083204.1|402698_403250_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl|CDD|274317
NC_021214.1|WP_004083209.1|405252_406218_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|380315
NC_021214.1|WP_004083210.1|406214_407225_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NC_021214.1|WP_004083181.1|387246_387690_-|transcriptional-regulator	unknown	unknown	gnl|CDD|224237
NC_021214.1|WP_004083186.1|389034_392037_-|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NC_021214.1|WP_004083208.1|403215_405171_+|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl|CDD|181342
NC_021214.1|WP_010865105.1|394551_395184_-|phosphate-propanoyltransferase	unknown	unknown	gnl|CDD|237899
NC_021214.1|WP_004083201.1|402072_402573_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|380325

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021214.1|WP_004083193.1|397245_398211_+|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	gnl|CDD|223318	COG0240, GpsA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	6.56418e-157
NC_021214.1|WP_004083198.1|400055_401405_+|dihydrolipoyl-dehydrogenase	gnl|CDD|273568	TIGR01350, Dihydrolipoyl_dehydrogenase, dihydrolipoamide dehydrogenase. This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.	0
NC_021214.1|WP_004083185.1|388586_389045_+|arginine-repressor	gnl|CDD|130592	TIGR01529, Arginine_repressor., arginine repressor. This model includes most members of the arginine-responsive transcriptional regulator family ArgR. This hexameric protein binds DNA at its amino end to repress arginine biosyntheis or activate arginine catabolism. Some species have several ArgR paralogs. In a neighbor-joining tree, some of these paralogous sequences show long branches and differ significantly in an otherwise well-conserved C-terminal region motif GT[VIL][AC]GDDT. These paralogs are excluded from the seed and score in the gray zone of this model, between trusted and noise cutoffs. [Amino acid biosynthesis, Glutamate family, Regulatory functions, DNA interactions].	1.02883e-68
NC_021214.1|WP_004083188.1|394077_394521_+|Hsp20/alpha-crystallin-family-protein	gnl|CDD|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	7.33553e-35
NC_021214.1|WP_004083177.1|385330_386008_+|TIGR00266-family-protein	gnl|CDD|224924	COG2013, COG2013, Uncharacterized conserved protein [Function unknown].	2.8083e-90
NC_021214.1|WP_004083197.1|399674_400010_+|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	6.03237e-20
NC_021214.1|WP_004083187.1|392270_394061_+|molecular-chaperone-DnaK	gnl|CDD|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NC_021214.1|WP_162487497.1|387686_388430_-|KaiC-domain-containing-protein	gnl|CDD|235281	PRK04328, PRK04328, hypothetical protein; Provisional.	6.71494e-172
NC_021214.1|WP_004083200.1|401381_402044_-|endonuclease-III-domain-containing-protein	gnl|CDD|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	5.31762e-96
NC_021214.1|WP_004083192.1|395218_395944_-|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	7.20423e-25
NC_021214.1|WP_004083179.1|386127_387237_+|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.28901e-38
NC_021214.1|WP_004083195.1|398318_399650_+|FAD-dependent-oxidoreductase	gnl|CDD|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	7.66022e-79
NC_021214.1|WP_004083204.1|402698_403250_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl|CDD|274317	TIGR02826, hypothetical_protein, anaerobic ribonucleoside-triphosphate reductase activating protein. Members of this family represent a set of radical SAM enzymes related to, yet architecturally different from, the activating protein for the glycine radical-containing, oxygen-sensitive ribonucleoside-triphosphate reductase (RNR) as described in model TIGR02491. Members of this family are found paired with members of a similarly divergent set of anaerobic ribonucleoside-triphosphate reductases. Identification of this protein as an RNR activitating protein is partly from pairing with a candidate RNR. It is further supported by our finding that upstream of these operons are examples of a conserved regulatory element (described Rodionov and Gelfand) that is found in nearly all bacteria and that occurs specifically upstream of operons for all three classes of RNR genes. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.14837e-67
NC_021214.1|WP_004083209.1|405252_406218_+|nitroreductase-family-protein	gnl|CDD|380315	cd02138, TdsD-like, nitroreductase similar to Burkholderia pseudomallei TdsD. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to Burkholderia pseudomallei TdsD, may be involved in the processing of organosulfur compounds. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.	4.86618e-81
NC_021214.1|WP_004083210.1|406214_407225_-|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	1.74909e-16
NC_021214.1|WP_004083181.1|387246_387690_-|transcriptional-regulator	gnl|CDD|224237	COG1318, COG1318, Predicted transcriptional regulators [Transcription].	1.14491e-38
NC_021214.1|WP_004083186.1|389034_392037_-|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_021214.1|WP_004083208.1|403215_405171_+|anaerobic-ribonucleoside-triphosphate-reductase	gnl|CDD|181342	PRK08271, PRK08271, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
NC_021214.1|WP_010865105.1|394551_395184_-|phosphate-propanoyltransferase	gnl|CDD|237899	PRK15070, PRK15070, phosphate propanoyltransferase.	4.76495e-131
NC_021214.1|WP_004083201.1|402072_402573_+|nitroreductase-family-protein	gnl|CDD|380325	cd02150, nitroreductase, nitroreductase family protein. A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.often found to be homodimers.	1.21885e-96

Protein sequences

>NC_021214.1|WP_004083192.1|395218_395944_-|sulfite-exporter-TauE/SafE-family-protein
MIVLVFLGGILAGFLNVLAGGGSMITLPILTALGLGIDVANGTNRIAIILQNLVAIERFKAKKVLKIKEAILVALPAIVGAILGSSIAVQIEKEMLQKIVGVIFLVMAVSLVWKPRIWLEDRFVKRNWVLIYIVFFLIGIYGGFIQAGVGFLLMPAIALLLGYELVKTNAVKVFIVASYNIISLVIFILNGKVNFLYGFILALGNMTGAWLAATFSIKKGANWVRWIVFTAVIVVGIRYVF
>NC_021214.1|WP_010865105.1|394551_395184_-|phosphate-propanoyltransferase
MITDGIMHKVREVYQLLRKEPGIIVGVSNRHVHLSREDLETLFGEGYELTPVKELRQPGQYAAKETVTIVGPKGAIENVRVLGPVRKETQVEISRTDAFRLGVRPPVRDSGDLEGTPGIVIIGPNGILVKEKGVIIAKRHIHMHPKDAEYYGVKDKDIVKVIVESGDRRLIFDDVLIRVREDFALEFHVDTDEANAAMLNTGDLVYIVEF
>NC_021214.1|WP_004083188.1|394077_394521_+|Hsp20/alpha-crystallin-family-protein
MLLGRREDIFRPFRELQREIDRLFDDFFRTEVRPAKEFFAPDMDVYETDDEVVIEVEIPGIDRKDVKITVEENILKISGEKKLEREQKGKNYYYVERSAGKFERAIRLPDYVDVEKIKAEYKNGVLTIRVPKKEERKKKVIEVEVQE
>NC_021214.1|WP_004083187.1|392270_394061_+|molecular-chaperone-DnaK
MAEKKEFVVGIDLGTTNSVIAWMKPDGTVEVIPNAEGSRVTPSVVAFTKSGEILVGEPAKRQMILNPERTIKSIKRKMGTDYKVRIDDKEYTPQEISAFILKKLKNDAEAYLGGEIKKAVITCPAYFNDAQRQATKEAGIIAGLEVLRIINEPTAAALAYGLDKAGKEEKVLVYDLGGGTFDVSILEIGEGVIEVIATAGNNHLGGDDFDQRLIDWMAEEFKKQHGIDLREDRQALQRLRDAAEKAKIELSTKMETDVSLPFIAVSPSGQPLHLEMRITRSLFESLTRDLVEMTRGPIEQALNDAKLSPQDIDEIILVGGMTRVPMVQRFIKEFFGKEPNKSVNPDEAVAIGAAIQAAILAGTEGAKGRDIVLVDVTPLTLGIEVKGGLFEPIIPRNTKIPVRKSKIFTTVEDGQTEVEIRVYQGERPIARENIFLGSFKLVGIPPAPRGVPQIEVTFDIDSDGIVHVSAKDLGSGKEQSMVVTGRHKLSEDEIKRMIEDAKRYEEQDKRLKEEIELKNRADDLAYSVEKTLKEHGDKIPADLKSRLEDMIRELRDAINRNDIPKVKMLFDDLQKESMKIGEYLYKSATGGETSNQ
>NC_021214.1|WP_004083186.1|389034_392037_-|efflux-RND-transporter-permease-subunit
MKIAEISSKRPIAIFMLLMAVVFLGFISFQHLKLDLLPQIEYPYAVVITTYMGAGTEEVEELVTKPLEGYISSTPGVRRFTSMSMDSVSFILVEFDWNVKTSEAVGRLSRYVDLATRDLPEGANPVVVEFDPSLLPVYAFSTEDDYEDVVSKIKRLPEVASVEVMGKPEKIVEVILDQEKIKRFDVDPSLIETILSGNLVYPFGYVSDSEGNIYPVSVDGRFENIEDLKNTIVGFRGVKYQSLLQGKVPNILVPVRLRNIAEVNITNESVQGEVRVNGKKASLIAIYKRSGANTVKTVREIKRILRDSKINYIEAMNQAYYTERAIDNLLKNLLYGFIAAFVVVLIFLKDFTSTIVTSFSIPLSLTITFVLLYAFGLNLDTLTLGGLIMALGMLVDNSIVVFENIYRHRSLGDPIPDAARKGAGEVWLAILASTLTTVSVFLPIVFFTGFVVRLFKYFAIAFVFALSSSLFVSTVVVPAGTRWIKPRRGKLTEALQKHYRKALEWCLKRKKLVLVISFALVAISVIYLLSKPLGFLPSFQTNLMVIDVKLPSQSSYEKTAEAVKQIEDYLNEHRNEYKISSFYAEVGITNVYSQIMGRGQNEARIMVNLGGSRREFAKNREKLKNAISQLNIPEAKIEVLEQSQQIYEILGYPVTIEVRGDDLSLIQEKAKEIFERLRKLQEVKKIQIRNSFEKEVLHVKIDRNKALMNGVVAGQVFLDLQTYLLGKKIGTLRTEEGTLPIVLKKAKFLSPEDLSKISLTGLKGDVPLGVVSNISRETLPSIVEHSDGERVVYVDLVSVEGSIGEVAKKVEKLLNEIDLSGVKVEITGQKSFMDEAFSELQYVVYIAIALVYMILAAQFESFVLPFVIFFTIPFAVVGVAFAVFVNGYSLNVPVLVGLLTLSGTVVNNAIVMLTRIEQIRQEKGLLEATLEGAQSRLRPILMTTFTTIVALLPTALSHAEGSEIESPISWVVIFGMLISMLFTLFVIPVIYAAIRRKVRV
>NC_021214.1|WP_004083185.1|388586_389045_+|arginine-repressor
MKISKKRRQELIRKIIHEKKISNQFQIVEELKKYGIKAVQPTVARDLKEIGAVKIMDESGNYVYKLLDETPVIDPWKELKRNFKSFVESIDRAGNLIVIKTIPGTASGIARVIDRLDIDEIVGTLAGDDTIFVAVRDPESCEKIVEKLSSIL
>NC_021214.1|WP_162487497.1|387686_388430_-|KaiC-domain-containing-protein
MGGGKMIKRVKTGIPGMDEILHGGIPERNIVLISGGPGTGKTIFSQQFIWNGLQMGEPGIYVALEEHPVQVKKNMEVFGWNVDPFEKEGKFAIVDAFTGGIGEYAEKEKYVVRDIDDVRELAEVLKRAVRETQAKRVVIDSVTTLYITKPAMARSIIFQLKRILSGLGCTSLFVSQVSVTEKGFGGPGVEHGVDGIIRLDLDEIDGELKRSLIVWKMRGTSHSMRRHPFEITDKGIVIYPSEGGEGR
>NC_021214.1|WP_004083181.1|387246_387690_-|transcriptional-regulator
MKLNFNPVTKEEIHQLETALLVGTLFRKEVLEEIRNSAERLTWVDSLAVAAGALARAKAGMTASEIAEELGRTEATIREHVKGETKAGKLVNETYELLKEGKLSVEGLIGEGIKVVTTTTGSDEKLQEVKKELEEIKQKLESVIQKL
>NC_021214.1|WP_004083179.1|386127_387237_+|MFS-transporter
MLFLTNVLRSMGTMSFNLLIQLRMKEIGATLFLIGLLSSLQGAMNTFSNVFWGRISDKIGKRKVFIILSLVLASAFYPLYAVIDVPSAILIVSMIIAFFNGMYPPAAMALSSTAKKMSLGFSLYNSSNSLGMLLSRISIGFLLMFMDLKLAFVFFSIVVAVSVIPALGLKEEKIQKKKEEDFHFGRKVMEHGIWALYLGSLLRQMGTSGSMSLIAVYLNERFHYSASTIGFITAVNPLVQIPSHFLFGKMVEKVDPKFISVLGIFMSSLVPFLMMIPENWAPVLAYAFLGASFGAFINGSNNFLGRRFHYLQRGRALGLLSSARFLGATIGPFLAGLLAEKSYSLMFSTLGLAVLSGGIVVLLFTKGGD
>NC_021214.1|WP_004083177.1|385330_386008_+|TIGR00266-family-protein
MKYEIVLKGSYALLKVFLSTGESVVVEPGAMVYMKGPIEVKTSATGGVWKALKRAILGGENFFMNTYISRGESEIGLAPQLPGDIDVIPLKDILYVQSTSFLACDPSVEMDVSFGGLKSFFSGEGIFLLKFIGHGDVAVSSFGGIKSVELQPGEEFTVDTGHVVAFDGTVKWNVRTFGGLKSTLFGGEGLVCTFTGPGRVYIQTRNYPAFVEWIKSLVPRQTGSR
>NC_021214.1|WP_004083193.1|397245_398211_+|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase
MRFFVLGAGSWGTVFAQMLHENGEEVILWARRKEIVDLINVSHTSPYVEESKITVRATNDLEEIKKEDILVIAIPVQYIREHLLRLPVKPSMVLNLSKGIEIKTGKRVSEIVEEILGCPYAVLSGPSHAEEVAKKLPTAVTLAGENSKELQKRISTEYFRVYTCEDVVGVEIAGALKNVIAIAAGILDGFGGWDNAKAALETRGIYEIARFGMFFGADQKTFMGLAGIGDLMVTCNSRYSRNRRFGELIARGFNPLKLLESSNQVVEGAFTVKAVMKIAKENKIDMPISEEVYRVVYEGKPPLQSMRDLMRRSLKDEFWAS
>NC_021214.1|WP_004083195.1|398318_399650_+|FAD-dependent-oxidoreductase
MRYDVVVVGGGPAGLVAAFTTKRFFGDKKILVVKKTEKEMVPCGIPYIFHTLGSVENDYMGIEDRFKGAGIDLLIDEVVDGNPDEKKLFTKSGKEISYDKLIIATGSSPNIPKIPGVDLKGVFTVPKEADYLKLLHEKVKDANDVVIIGGGFIGVEVADEIKKSGKNVTLVEIMDSLLPVSFDPDFGELARKELESDNVKVLTGRKVTEILGTEKVEGVKLDSGETIPADVVVLATGYKPNSELARKLGLKVTELGFIETDEYMRTSKPDIFAAGDCVQHKDFLTGKPSRLMLASAAVFDARIAASNLYGLKVIRTNKGSLNAYSTVIGSKAFGSVGITERIAKEEGFEVVVGKAEAPDRHPGKFEDTSKLVVKLIFSEDSKILLGAQVCGGKSVGEIVNLISLGIQKGITANDLFTMQIGTHPLLTSAPTVYPLAKAAEMVL
>NC_021214.1|WP_004083197.1|399674_400010_+|carboxymuconolactone-decarboxylase-family-protein
MAAKEKLEQIQKQLQEIIGKAPEIGKFAEYVHAAESPKALDTKTKELISLGIAVAVRCEPCIVWHAGAAVRAGATEEEILDTIKVAVCMGGGPALMYGLKAYEIALEFLGK
>NC_021214.1|WP_004083198.1|400055_401405_+|dihydrolipoyl-dehydrogenase
MYDAVIIGGGPGGYVCAIKLAQLGKKVALVEKDALGGTCTNRGCIPTKAMLTVSHLMDEMKEKASKYGLKVSGVEYDVAAIMKHVQKSVMMSRKGIEYLLKKNGVEVFKGTAVVENKNTVVVQETGEKLEAKNLVLAHGSVPSVFSPFDIDGVWTSDDVFNLKEFPKSLVIVGGGVIGVEFATFFGSFGVDVTIVEIAEHILPYEDSDVAEEVKKALKRKGVKILEKTKISSLSKVDDGFEVALENGETLKAEKVLLAAGRKPNIPEDVKALGVKIEKGVVTDSRMRTNVENVYAIGDIRSGIMLAHVAMYEGIVAAKNIAGEEEEMDYSAVPSIIFSSPEVASVGVREKDVNPEEVVISKFPVSANGRARTMLENIGFAKVIADKKDGTVLGMSIVSPSATDMIMEGVIAVKFRMKAEDLEKAIHPHPTLTETILGALEGVSGKPIHL
>NC_021214.1|WP_004083200.1|401381_402044_-|endonuclease-III-domain-containing-protein
MRLTELYRKLLEIHGSVGKWWPGTPEEIVITAVLTQNTNWKNVERAMENIKNEVKGNNLLKELDSLPEEKVAELIRPAGFFNIKTKRLKELLKFLKEYNYNLSRLRDLPTHILRERLLKIKGIGKETADAILLYALEKPVFVVDSYTRRLLKRIFNIELNDYDEVQKLFMTHYPEDVRLYQEFHGLIVEHAKKFCSKTPKCGVCPLKKECCHVSQMNGFS
>NC_021214.1|WP_004083201.1|402072_402573_+|nitroreductase-family-protein
MSIIYRRRSIRKYQKKDVPDELVKEIIRAAMHAPSACNQQPWHFVVIRNEETKKKIAEIHPHAQMSAEAPVVILVCGDPTLEKCKGYWIQDCSAAVENLLLRATELGLGAVWCGVYPREERVKAFRELLGIPEHVVPFALVPVGYPAEHPVQVDRFKPERIHYEKW
>NC_021214.1|WP_004083204.1|402698_403250_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MYVNRIGTFRDHPDLYGVSVYFQGCDAKPKCYMCHNPETWHLSEEYKRPSEVVTKIIDEKLSSLLRYFPKAALVFLGGEPLAPYNREEMLSLSKMFKEKYGERLTVVLFTWRLPKDIVKENLLKYVQYVDEFVMGRYLHTYRRDGFPASKNQIHIDRRTFERMIEAVLRRGHYEGSVFVRKRI
>NC_021214.1|WP_004083208.1|403215_405171_+|anaerobic-ribonucleoside-triphosphate-reductase
MKVQYSFEREFEELMSDLLSKYGYEMFQMDGLGDQLDVVKFTEDFVRRGIIESTIDANANVRVTNISTYFIEISKPHTYLYSLYRIWQKMKEMFGKGVADEFVEAQINGAVYLHDRHHAALMPYCFAYTLKPIVEKGLPFIKTIKSEPAKHLSTFIQHVIQFVMFASNQSSGAVGLPDFFVWMWYFVKKDLKEGIIPRDKLDWYIEQHFQILTYSLNQPIRTTQSPYTNFTYLDRNYIKAIFEGERYPDGSLITDHVEDIIALQKHYWEWVSRERERQMFTFPVLTASLLYKDGKFLDEDSARFINKINMKWQDTNWYISDSIDAVASCCRLTSSTQTLKKFSLSSEEEEKLKGRMNSIGGSDLNIGSFKVITVNLPRIALESGGDREKYLQILRHRVQLIKKALAAVREIIKERISEGLLPLYENGLMLLNRQYGTIGVTGVWESASIMGLTTEDIDGLKYTEEGEVFVDNVLDTIREEAEKGYHEYGFTFNIEQVPAEKAAVTLAQKDRFLFGEKQPFEIYSNQWVPLMANTDVLNRIRYSGKWDKKVSGGAILHINLGESFKTEEESFNMVKMIADMGVMYFAFNTKISVCEDGHAFYGERCPVCGKAKVDEYMRIVGYLVPVSAFNKERREIEYPRRQFYDSLTIRR
>NC_021214.1|WP_004083209.1|405252_406218_+|nitroreductase-family-protein
MRVKHFELLTDEGKTFTHVDLYGKYTILFFFPKAGTSGCTREAVEFSRENFEKAQVVGISRDSVEALKRFKEKNDLKVTLLSDPEGILHEFFNVLENGKTVRSTFLIDRWGFVRKEWRRVKVEGHVQEVKEALDRLIEEDLSLNKHIEWRRARRALKKDRVPREELELLIKAAHLAPSCMNNQPWRFVVVDEEELLKKIHEALPGGNYWMKNAPALIAVHSKKDFDCALPDNRDYFLFDTGLAVGNLLVQATQMGLVAHPVAGYDPVKVKEILKIPEDHVLITLIAVGYLGDESELSEKHRELERSERVRKELSEIVRWNL
>NC_021214.1|WP_004083210.1|406214_407225_-|ABC-transporter-permease
MSEFLALFSAMWKESWRDKISTFFSIAFPVMFLLIFGFLFGGSGNSVKTAVVTVDYDLSDFGDVYTSLEELKGYYHEVAVVEKERIIFIRNTTDEYYQSLLDSWEISLKNKVTRLLNGLNPVIMVKKEVLKTARELTSFDYTLTGVIAVSLLSIGLFGTVDVFSRYRERGFLKRLKATPVGNFSFVFGLISARMFYGILSTALIMLLGTLIFKASYELNVFLFLISVVSSVLSFIALGALISILFKKSDVATDAAVILFTIMMFLTGVYFPVSFLPDYLRVVSYFLPVKYGVELIRYSLGFEIFPFSRYLITAVIMFLAGLMFVFYTASLVLRKED

Crispr_ID: NC_021214_4

• CRISPR_ID: NC_021214_4
• CRISPR_location: 409300-410928
• CRISPR_type: Orphan
• Repeat_type: III-A
• Spacer_info: 24 spacers

Consensus repeat of NC_021214_4

Consensus_repeat	Method
GTTTCCATACCTCTAAGGAATTATTGAAAC	CRISPRCasFinder
GTTTCCATACCTCTAAGGAATTATTGAAAC	CRT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	PILER-CR

spacers of NC_021214_4

>4.1|409330|39|NC_021214|CRISPRCasFinder,CRT
CTGAAAGAGGGAACGAATGTGTTTATGCGACGAAAACTG
>4.2|409399|35|NC_021214|CRISPRCasFinder,CRT,PILER-CR
TTTGGGAAGAGGAGGGAGAACATGAGGATAAGTGA
>4.3|409464|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
TAATCAAAATGTATCCAGACGGAACATCTAAAGAATT
>4.4|409531|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
TTCCAGTCCAACCGTCGACTGAGTGTGAATGACTCCC
>4.5|409598|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
CACCCGTGATGTCTATCGTGTTGCCTGTCGTTACCG
>4.6|409664|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
GCGTTTCCACTCGTATCTATCGCTCTCACACGGAAG
>4.7|409730|42|NC_021214|CRISPRCasFinder,CRT,PILER-CR
TTGTGCCTGTAAAGGGGACAGTAGATACTGAAAGTTTATATT
>4.8|409802|35|NC_021214|CRISPRCasFinder,CRT,PILER-CR
CCGACAGCGAATCAGCGAATCCCCACGATGGTGCG
>4.9|409867|39|NC_021214|CRISPRCasFinder,CRT,PILER-CR
AGGTGCAATCGCAGGCATCTGGAAGCTCCAGAACAAAGG
>4.10|409936|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
CAGAGTAATGAGAGGAGTCATATTTGAAATCGATGA
>4.11|410002|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
CCGGAAGTAGTAGGGTTCGTCGCCGGGCTCTGTGAT
>4.12|410068|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
GTCTGAACTCTGCCTTGAACAATGCCTCCGAAGAAT
>4.13|410134|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
CATTTGTAGCACTATCATAAGTCAGAGTTTTCCCCG
>4.14|410200|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
AGGAAACGAATACGAAATCTGGATAAGAGAAGCAGA
>4.15|410266|35|NC_021214|CRISPRCasFinder,CRT,PILER-CR
TATTGTGCTTTTGTTCAGAATGCTTTCGAGTCTGT
>4.16|410331|38|NC_021214|CRISPRCasFinder,CRT,PILER-CR
TTTGAGCCTGATCGGGATAGCAGAGAACTTCACGTGCT
>4.17|410399|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
GTGTCCTTCAGTAGCAAATGGAGCTACAGGAAGAGC
>4.18|410465|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
ACTTGAAAGTGCTTGAAAAAGTTGTGGAATAGCGCTA
>4.19|410532|35|NC_021214|CRISPRCasFinder,CRT,PILER-CR
TGCGAAGGATTGTGGTAGAGCATATGAAGTATATA
>4.20|410597|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
ATCCATTCACAATCCCGACATTGTGAAGCCAACCACG
>4.21|410664|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
AAGTACACATCAACCATTGTCCCTTCTGTTACCTGG
>4.22|410730|35|NC_021214|CRISPRCasFinder,CRT,PILER-CR
TCGATGCGATGGGGTGATAGGGTGCTTCGATGGAA
>4.23|410795|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
AAGGCAGATCTGAGGATCATTGCAGAGCGAGGAAACA
>4.24|410862|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
GAAGAAAGGAGGATGAGGAAGATGGGAAAAGAGAACC

CRISPR arrays and Neighbor proteins around NC_021214_4

CRISPR arrays

The CRISPR arrays of NC_021214_4

>merge|NC_021214|4|409300-410928|CRISPRCasFinder,CRT,PILER-CR
GTTTCCGTACCTCTAAGGAAGTATTGAAACCTGAAAGAGGGAACGAATGTGTTTATGCGACGAAAACTGGTTTCCATACCTCTAAGGAACTATTGAAACTTTGGGAAGAGGAGGGAGAACATGAGGATAAGTGAGTTTCCATACCTCTAAGGAATTATTGAAACTAATCAAAATGTATCCAGACGGAACATCTAAAGAATTGTTTCCATACCTCTAAGGAATTATTGAAACTTCCAGTCCAACCGTCGACTGAGTGTGAATGACTCCCGTTTCCATACCTCTAAGGAATTATTGAAACCACCCGTGATGTCTATCGTGTTGCCTGTCGTTACCGGTTTCCATACCTCTAAGGAATTATTGAAACGCGTTTCCACTCGTATCTATCGCTCTCACACGGAAGGTTTCCATACCTCTAAGGAATTATTGAAACTTGTGCCTGTAAAGGGGACAGTAGATACTGAAAGTTTATATTGTTTCCATACCTCTAAGGAATTATTGAAACCCGACAGCGAATCAGCGAATCCCCACGATGGTGCGGTTTCCATACCTCTAAGGAATTATTGAAACAGGTGCAATCGCAGGCATCTGGAAGCTCCAGAACAAAGGGTTTCCATACCTCTAAGGAATTATTGAAACCAGAGTAATGAGAGGAGTCATATTTGAAATCGATGAGTTTCCATACCTCTAAGGAATTATTGAAACCCGGAAGTAGTAGGGTTCGTCGCCGGGCTCTGTGATGTTTCCATACCTCTAAGGAATTATTGAAACGTCTGAACTCTGCCTTGAACAATGCCTCCGAAGAATGTTTCCATACCTCTAAGGAATTATTGAAACCATTTGTAGCACTATCATAAGTCAGAGTTTTCCCCGGTTTCCATACCTCTAAGGAATTATTGAAACAGGAAACGAATACGAAATCTGGATAAGAGAAGCAGAGTTTCCATACCTCTAAGGAATTATTGAAACTATTGTGCTTTTGTTCAGAATGCTTTCGAGTCTGTGTTTCCATACCTCTAAGGAATTATTGAAACTTTGAGCCTGATCGGGATAGCAGAGAACTTCACGTGCTGTTTCCATACCTCTAAGGAATTATTGAAACGTGTCCTTCAGTAGCAAATGGAGCTACAGGAAGAGCGTTTCCATACCTCTAAGGAATTATTGAAACACTTGAAAGTGCTTGAAAAAGTTGTGGAATAGCGCTAGTTTCCATACCTCTAAGGAATTATTGAAACTGCGAAGGATTGTGGTAGAGCATATGAAGTATATAGTTTCCATACCTCTAAGGAATTATTGAAACATCCATTCACAATCCCGACATTGTGAAGCCAACCACGGTTTCCATACCTCTAAGGAATTATTGAAACAAGTACACATCAACCATTGTCCCTTCTGTTACCTGGGTTTCCATACCTCTAAGGAATTATTGAAACTCGATGCGATGGGGTGATAGGGTGCTTCGATGGAAGTTTCCATACCTCTAAGGAATTATTGAAACAAGGCAGATCTGAGGATCATTGCAGAGCGAGGAAACAGTTTCCATACCTCTAAGGAATTATTGAAACGAAGAAAGGAGGATGAGGAAGATGGGAAAAGAGAACCGTTTCCATACCTCTAAGGAATTATTGAAAC

>NC_021214|4|4|409300-410928|CRISPRCasFinder
GTTTCCGTACCTCTAAGGAAGTATTGAAAC	CTGAAAGAGGGAACGAATGTGTTTATGCGACGAAAACTG
GTTTCCATACCTCTAAGGAACTATTGAAAC	TTTGGGAAGAGGAGGGAGAACATGAGGATAAGTGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TAATCAAAATGTATCCAGACGGAACATCTAAAGAATT
GTTTCCATACCTCTAAGGAATTATTGAAAC	TTCCAGTCCAACCGTCGACTGAGTGTGAATGACTCCC
GTTTCCATACCTCTAAGGAATTATTGAAAC	CACCCGTGATGTCTATCGTGTTGCCTGTCGTTACCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	GCGTTTCCACTCGTATCTATCGCTCTCACACGGAAG
GTTTCCATACCTCTAAGGAATTATTGAAAC	TTGTGCCTGTAAAGGGGACAGTAGATACTGAAAGTTTATATT
GTTTCCATACCTCTAAGGAATTATTGAAAC	CCGACAGCGAATCAGCGAATCCCCACGATGGTGCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGGTGCAATCGCAGGCATCTGGAAGCTCCAGAACAAAGG
GTTTCCATACCTCTAAGGAATTATTGAAAC	CAGAGTAATGAGAGGAGTCATATTTGAAATCGATGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	CCGGAAGTAGTAGGGTTCGTCGCCGGGCTCTGTGAT
GTTTCCATACCTCTAAGGAATTATTGAAAC	GTCTGAACTCTGCCTTGAACAATGCCTCCGAAGAAT
GTTTCCATACCTCTAAGGAATTATTGAAAC	CATTTGTAGCACTATCATAAGTCAGAGTTTTCCCCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGGAAACGAATACGAAATCTGGATAAGAGAAGCAGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TATTGTGCTTTTGTTCAGAATGCTTTCGAGTCTGT
GTTTCCATACCTCTAAGGAATTATTGAAAC	TTTGAGCCTGATCGGGATAGCAGAGAACTTCACGTGCT
GTTTCCATACCTCTAAGGAATTATTGAAAC	GTGTCCTTCAGTAGCAAATGGAGCTACAGGAAGAGC
GTTTCCATACCTCTAAGGAATTATTGAAAC	ACTTGAAAGTGCTTGAAAAAGTTGTGGAATAGCGCTA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TGCGAAGGATTGTGGTAGAGCATATGAAGTATATA
GTTTCCATACCTCTAAGGAATTATTGAAAC	ATCCATTCACAATCCCGACATTGTGAAGCCAACCACG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAGTACACATCAACCATTGTCCCTTCTGTTACCTGG
GTTTCCATACCTCTAAGGAATTATTGAAAC	TCGATGCGATGGGGTGATAGGGTGCTTCGATGGAA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAGGCAGATCTGAGGATCATTGCAGAGCGAGGAAACA
GTTTCCATACCTCTAAGGAATTATTGAAAC	GAAGAAAGGAGGATGAGGAAGATGGGAAAAGAGAACC
GTTTCCATACCTCTAAGGAATTATTGAAAC

>NC_021214|4|4|409300-410928|CRT
GTTTCCGTACCTCTAAGGAAGTATTGAAAC	CTGAAAGAGGGAACGAATGTGTTTATGCGACGAAAACTG
GTTTCCATACCTCTAAGGAACTATTGAAAC	TTTGGGAAGAGGAGGGAGAACATGAGGATAAGTGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TAATCAAAATGTATCCAGACGGAACATCTAAAGAATT
GTTTCCATACCTCTAAGGAATTATTGAAAC	TTCCAGTCCAACCGTCGACTGAGTGTGAATGACTCCC
GTTTCCATACCTCTAAGGAATTATTGAAAC	CACCCGTGATGTCTATCGTGTTGCCTGTCGTTACCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	GCGTTTCCACTCGTATCTATCGCTCTCACACGGAAG
GTTTCCATACCTCTAAGGAATTATTGAAAC	TTGTGCCTGTAAAGGGGACAGTAGATACTGAAAGTTTATATT
GTTTCCATACCTCTAAGGAATTATTGAAAC	CCGACAGCGAATCAGCGAATCCCCACGATGGTGCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGGTGCAATCGCAGGCATCTGGAAGCTCCAGAACAAAGG
GTTTCCATACCTCTAAGGAATTATTGAAAC	CAGAGTAATGAGAGGAGTCATATTTGAAATCGATGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	CCGGAAGTAGTAGGGTTCGTCGCCGGGCTCTGTGAT
GTTTCCATACCTCTAAGGAATTATTGAAAC	GTCTGAACTCTGCCTTGAACAATGCCTCCGAAGAAT
GTTTCCATACCTCTAAGGAATTATTGAAAC	CATTTGTAGCACTATCATAAGTCAGAGTTTTCCCCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGGAAACGAATACGAAATCTGGATAAGAGAAGCAGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TATTGTGCTTTTGTTCAGAATGCTTTCGAGTCTGT
GTTTCCATACCTCTAAGGAATTATTGAAAC	TTTGAGCCTGATCGGGATAGCAGAGAACTTCACGTGCT
GTTTCCATACCTCTAAGGAATTATTGAAAC	GTGTCCTTCAGTAGCAAATGGAGCTACAGGAAGAGC
GTTTCCATACCTCTAAGGAATTATTGAAAC	ACTTGAAAGTGCTTGAAAAAGTTGTGGAATAGCGCTA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TGCGAAGGATTGTGGTAGAGCATATGAAGTATATA
GTTTCCATACCTCTAAGGAATTATTGAAAC	ATCCATTCACAATCCCGACATTGTGAAGCCAACCACG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAGTACACATCAACCATTGTCCCTTCTGTTACCTGG
GTTTCCATACCTCTAAGGAATTATTGAAAC	TCGATGCGATGGGGTGATAGGGTGCTTCGATGGAA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAGGCAGATCTGAGGATCATTGCAGAGCGAGGAAACA
GTTTCCATACCTCTAAGGAATTATTGAAAC	GAAGAAAGGAGGATGAGGAAGATGGGAAAAGAGAACC
GTTTCCATACCTCTAAGGAATTATTGAAAC

>NC_021214|4|4|409369-410928|PILER-CR
GTTTCCATACCTCTAAGGAACTATTGAAAC	TTTGGGAAGAGGAGGGAGAACATGAGGATAAGTGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TAATCAAAATGTATCCAGACGGAACATCTAAAGAATT
GTTTCCATACCTCTAAGGAATTATTGAAAC	TTCCAGTCCAACCGTCGACTGAGTGTGAATGACTCCC
GTTTCCATACCTCTAAGGAATTATTGAAAC	CACCCGTGATGTCTATCGTGTTGCCTGTCGTTACCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	GCGTTTCCACTCGTATCTATCGCTCTCACACGGAAG
GTTTCCATACCTCTAAGGAATTATTGAAAC	TTGTGCCTGTAAAGGGGACAGTAGATACTGAAAGTTTATATT
GTTTCCATACCTCTAAGGAATTATTGAAAC	CCGACAGCGAATCAGCGAATCCCCACGATGGTGCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGGTGCAATCGCAGGCATCTGGAAGCTCCAGAACAAAGG
GTTTCCATACCTCTAAGGAATTATTGAAAC	CAGAGTAATGAGAGGAGTCATATTTGAAATCGATGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	CCGGAAGTAGTAGGGTTCGTCGCCGGGCTCTGTGAT
GTTTCCATACCTCTAAGGAATTATTGAAAC	GTCTGAACTCTGCCTTGAACAATGCCTCCGAAGAAT
GTTTCCATACCTCTAAGGAATTATTGAAAC	CATTTGTAGCACTATCATAAGTCAGAGTTTTCCCCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGGAAACGAATACGAAATCTGGATAAGAGAAGCAGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TATTGTGCTTTTGTTCAGAATGCTTTCGAGTCTGT
GTTTCCATACCTCTAAGGAATTATTGAAAC	TTTGAGCCTGATCGGGATAGCAGAGAACTTCACGTGCT
GTTTCCATACCTCTAAGGAATTATTGAAAC	GTGTCCTTCAGTAGCAAATGGAGCTACAGGAAGAGC
GTTTCCATACCTCTAAGGAATTATTGAAAC	ACTTGAAAGTGCTTGAAAAAGTTGTGGAATAGCGCTA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TGCGAAGGATTGTGGTAGAGCATATGAAGTATATA
GTTTCCATACCTCTAAGGAATTATTGAAAC	ATCCATTCACAATCCCGACATTGTGAAGCCAACCACG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAGTACACATCAACCATTGTCCCTTCTGTTACCTGG
GTTTCCATACCTCTAAGGAATTATTGAAAC	TCGATGCGATGGGGTGATAGGGTGCTTCGATGGAA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAGGCAGATCTGAGGATCATTGCAGAGCGAGGAAACA
GTTTCCATACCTCTAAGGAATTATTGAAAC	GAAGAAAGGAGGATGAGGAAGATGGGAAAAGAGAACC
GTTTCCATACCTCTAAGGAATTATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021214.1|WP_010865109.1|408299_409205_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_021214.1|WP_004083198.1|400055_401405_+|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl|CDD|273568
NC_021214.1|WP_004083238.1|421311_421866_-|thymidine-kinase	unknown	unknown	gnl|CDD|224352
NC_021214.1|WP_004083233.1|419452_420130_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_021214.1|WP_004083223.1|413951_414689_-|hypothetical-protein	unknown	unknown	gnl|CDD|238481
NC_021214.1|WP_004083219.1|412809_413925_+|ROK-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224851
NC_021214.1|WP_004083197.1|399674_400010_+|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|223672
NC_021214.1|WP_004083229.1|416402_417926_-|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|223147
NC_021214.1|WP_004083200.1|401381_402044_-|endonuclease-III-domain-containing-protein	unknown	unknown	gnl|CDD|225140
NC_021214.1|WP_004083236.1|420110_421328_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_021214.1|WP_004083231.1|417918_419052_-|glutamine-amidotransferase-family-protein	unknown	unknown	gnl|CDD|238888
NC_021214.1|WP_004083208.1|403215_405171_+|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl|CDD|181342
NC_021214.1|WP_004083215.1|411584_412805_+|glycosyltransferase	unknown	unknown	gnl|CDD|340823
NC_021214.1|WP_004083211.1|407217_408303_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|378925
NC_021214.1|WP_004083209.1|405252_406218_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|380315
NC_021214.1|WP_004083204.1|402698_403250_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl|CDD|274317
NC_021214.1|WP_004083225.1|414676_415954_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224171
NC_021214.1|WP_004083210.1|406214_407225_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NC_021214.1|WP_004083227.1|415950_416406_-|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|319885
NC_021214.1|WP_004083201.1|402072_402573_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|380325

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021214.1|WP_010865109.1|408299_409205_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.16546e-99
NC_021214.1|WP_004083198.1|400055_401405_+|dihydrolipoyl-dehydrogenase	gnl|CDD|273568	TIGR01350, Dihydrolipoyl_dehydrogenase, dihydrolipoamide dehydrogenase. This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.	0
NC_021214.1|WP_004083238.1|421311_421866_-|thymidine-kinase	gnl|CDD|224352	COG1435, Tdk, Thymidine kinase [Nucleotide transport and metabolism].	4.2679e-80
NC_021214.1|WP_004083233.1|419452_420130_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	8.28534e-86
NC_021214.1|WP_004083223.1|413951_414689_-|hypothetical-protein	gnl|CDD|238481	cd00981, arch_gltB, Archaeal-type gltB domain. This domain shares sequence similarity with a region of unknown function found in the large subunit of glutamate synthase, which is encoded by gltB and found in most bacteria and eukaryotes. It is predicted to be homologous to the C-terminal domain of glutamate synthase based upon sequence similarity coupled with genome organization data, showing that this domain is found in a gene cluster with other domains of Glts, which are annotated. This domain is found primarily in archaea, but is also present in a few bacteria, likely as a result of lateral gene transfer.	2.18871e-127
NC_021214.1|WP_004083219.1|412809_413925_+|ROK-family-transcriptional-regulator	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	2.49012e-42
NC_021214.1|WP_004083197.1|399674_400010_+|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	6.03237e-20
NC_021214.1|WP_004083229.1|416402_417926_-|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|223147	COG0069, GltB, Glutamate synthase domain 2 [Amino acid transport and metabolism].	0
NC_021214.1|WP_004083200.1|401381_402044_-|endonuclease-III-domain-containing-protein	gnl|CDD|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	5.31762e-96
NC_021214.1|WP_004083236.1|420110_421328_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.91899e-53
NC_021214.1|WP_004083231.1|417918_419052_-|glutamine-amidotransferase-family-protein	gnl|CDD|238888	cd01907, GlxB, Glutamine amidotransferases class-II (Gn-AT)_GlxB-type. GlxB is a glutamine amidotransferase-like protein of unknown function found in bacteria and archaea. GlxB has a structural fold similar to that of other class II glutamine amidotransferases including glucosamine-fructose 6-phosphate synthase (GLMS or GFAT), glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase), asparagine synthetase B (AsnB), beta lactam synthetase (beta-LS) and glutamate synthase (GltS). The GlxB fold is also somewhat similar to the Ntn (N-terminal nucleophile) hydrolase fold of the proteasomal alpha and beta subunits.	9.03379e-111
NC_021214.1|WP_004083208.1|403215_405171_+|anaerobic-ribonucleoside-triphosphate-reductase	gnl|CDD|181342	PRK08271, PRK08271, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
NC_021214.1|WP_004083215.1|411584_412805_+|glycosyltransferase	gnl|CDD|340823	cd03792, GT4_trehalose_phosphorylase, trehalose phosphorylase and similar proteins. Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.	0
NC_021214.1|WP_004083211.1|407217_408303_-|ABC-transporter-permease	gnl|CDD|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	1.92003e-15
NC_021214.1|WP_004083209.1|405252_406218_+|nitroreductase-family-protein	gnl|CDD|380315	cd02138, TdsD-like, nitroreductase similar to Burkholderia pseudomallei TdsD. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to Burkholderia pseudomallei TdsD, may be involved in the processing of organosulfur compounds. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.	4.86618e-81
NC_021214.1|WP_004083204.1|402698_403250_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl|CDD|274317	TIGR02826, hypothetical_protein, anaerobic ribonucleoside-triphosphate reductase activating protein. Members of this family represent a set of radical SAM enzymes related to, yet architecturally different from, the activating protein for the glycine radical-containing, oxygen-sensitive ribonucleoside-triphosphate reductase (RNR) as described in model TIGR02491. Members of this family are found paired with members of a similarly divergent set of anaerobic ribonucleoside-triphosphate reductases. Identification of this protein as an RNR activitating protein is partly from pairing with a candidate RNR. It is further supported by our finding that upstream of these operons are examples of a conserved regulatory element (described Rodionov and Gelfand) that is found in nearly all bacteria and that occurs specifically upstream of operons for all three classes of RNR genes. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.14837e-67
NC_021214.1|WP_004083225.1|414676_415954_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224171	COG1251, NirB, NAD(P)H-nitrite reductase [Energy production and conversion].	2.84038e-84
NC_021214.1|WP_004083210.1|406214_407225_-|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	1.74909e-16
NC_021214.1|WP_004083227.1|415950_416406_-|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|319885	cd10563, CooF_like, CooF, iron-sulfur subunit of carbon monoxide dehydrogenase. This family includes CooF, the iron-sulfur subunit of carbon monoxide dehydrogenase (CODH), found in anaerobic bacteria and archaea. Carbon monoxide dehydrogenase is a key enzyme for carbon monoxide (CO) metabolism, where CooF is the proposed mediator of electron transfer between CODH and the CO-induced hydrogenase, catalyzing the reaction that uses CO as a single carbon and energy source, and producing only H2 and CO2. The ion-sulfur subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons in the protein complex during reaction.	1.75166e-65
NC_021214.1|WP_004083201.1|402072_402573_+|nitroreductase-family-protein	gnl|CDD|380325	cd02150, nitroreductase, nitroreductase family protein. A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.often found to be homodimers.	1.21885e-96

Protein sequences

>NC_021214.1|WP_010865109.1|408299_409205_-|ABC-transporter-ATP-binding-protein
MVVLHSKGGFFLEILKVVDLKKHYGDVKAVDGISFTVERGTVFSFLGPNGAGKTTTVEILEGLRKKDSGEIYYFGERKDVLDRETKRKIGVCLQKSAFFENLTVWETLKLFRGLYGTGLDLKEVMGLFSLENIEKKMVKTLSGGQLQRLAVAVAFINDPEIVFLDEPTTGLDPQARRQIWDTIEHFKNLGKTIFLTTHYMEEAERLSDHVCIIDHGKIIAEGTPSSLISSSGLKTVVEFDCDQDVNVRYLEKKENHYVVETDAPEELIKDLLKNWNVSNIVIRKPNLEDVFLKLTGRDLRE
>NC_021214.1|WP_004083211.1|407217_408303_-|ABC-transporter-permease
MRHLVVSILKNDYFRTKSVLFWNFLFPILLYLILVSIFGDMSSNMNLRIGLVGESSLVESVFSHLPSGIEIIRTQNPERDLKYGKIDVCVILPENFDNLFTKAIIFSKTKISVPVEITILYAPERQESIVLANVVSNILESLDLQLRKVKEVEVEYRKKERQAINYSHYILPAVLLVGVMSVGLFTVPYQLALYREQGILKRILASPLRGHHYFFSIVVCGLFAMSITSASVTLFARFVYGIEFPINVSFLGGVLLSFLTFLSVSLLMVSLFKTFSALSAASQVFNQVFMFLGGFYFDVSGIPWPIKAVVLGNPATYLVDYLRGSFGYRTIYSNHFLVPIVWIVLSFVLFFLNWRRVMMVE
>NC_021214.1|WP_004083210.1|406214_407225_-|ABC-transporter-permease
MSEFLALFSAMWKESWRDKISTFFSIAFPVMFLLIFGFLFGGSGNSVKTAVVTVDYDLSDFGDVYTSLEELKGYYHEVAVVEKERIIFIRNTTDEYYQSLLDSWEISLKNKVTRLLNGLNPVIMVKKEVLKTARELTSFDYTLTGVIAVSLLSIGLFGTVDVFSRYRERGFLKRLKATPVGNFSFVFGLISARMFYGILSTALIMLLGTLIFKASYELNVFLFLISVVSSVLSFIALGALISILFKKSDVATDAAVILFTIMMFLTGVYFPVSFLPDYLRVVSYFLPVKYGVELIRYSLGFEIFPFSRYLITAVIMFLAGLMFVFYTASLVLRKED
>NC_021214.1|WP_004083209.1|405252_406218_+|nitroreductase-family-protein
MRVKHFELLTDEGKTFTHVDLYGKYTILFFFPKAGTSGCTREAVEFSRENFEKAQVVGISRDSVEALKRFKEKNDLKVTLLSDPEGILHEFFNVLENGKTVRSTFLIDRWGFVRKEWRRVKVEGHVQEVKEALDRLIEEDLSLNKHIEWRRARRALKKDRVPREELELLIKAAHLAPSCMNNQPWRFVVVDEEELLKKIHEALPGGNYWMKNAPALIAVHSKKDFDCALPDNRDYFLFDTGLAVGNLLVQATQMGLVAHPVAGYDPVKVKEILKIPEDHVLITLIAVGYLGDESELSEKHRELERSERVRKELSEIVRWNL
>NC_021214.1|WP_004083208.1|403215_405171_+|anaerobic-ribonucleoside-triphosphate-reductase
MKVQYSFEREFEELMSDLLSKYGYEMFQMDGLGDQLDVVKFTEDFVRRGIIESTIDANANVRVTNISTYFIEISKPHTYLYSLYRIWQKMKEMFGKGVADEFVEAQINGAVYLHDRHHAALMPYCFAYTLKPIVEKGLPFIKTIKSEPAKHLSTFIQHVIQFVMFASNQSSGAVGLPDFFVWMWYFVKKDLKEGIIPRDKLDWYIEQHFQILTYSLNQPIRTTQSPYTNFTYLDRNYIKAIFEGERYPDGSLITDHVEDIIALQKHYWEWVSRERERQMFTFPVLTASLLYKDGKFLDEDSARFINKINMKWQDTNWYISDSIDAVASCCRLTSSTQTLKKFSLSSEEEEKLKGRMNSIGGSDLNIGSFKVITVNLPRIALESGGDREKYLQILRHRVQLIKKALAAVREIIKERISEGLLPLYENGLMLLNRQYGTIGVTGVWESASIMGLTTEDIDGLKYTEEGEVFVDNVLDTIREEAEKGYHEYGFTFNIEQVPAEKAAVTLAQKDRFLFGEKQPFEIYSNQWVPLMANTDVLNRIRYSGKWDKKVSGGAILHINLGESFKTEEESFNMVKMIADMGVMYFAFNTKISVCEDGHAFYGERCPVCGKAKVDEYMRIVGYLVPVSAFNKERREIEYPRRQFYDSLTIRR
>NC_021214.1|WP_004083204.1|402698_403250_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MYVNRIGTFRDHPDLYGVSVYFQGCDAKPKCYMCHNPETWHLSEEYKRPSEVVTKIIDEKLSSLLRYFPKAALVFLGGEPLAPYNREEMLSLSKMFKEKYGERLTVVLFTWRLPKDIVKENLLKYVQYVDEFVMGRYLHTYRRDGFPASKNQIHIDRRTFERMIEAVLRRGHYEGSVFVRKRI
>NC_021214.1|WP_004083201.1|402072_402573_+|nitroreductase-family-protein
MSIIYRRRSIRKYQKKDVPDELVKEIIRAAMHAPSACNQQPWHFVVIRNEETKKKIAEIHPHAQMSAEAPVVILVCGDPTLEKCKGYWIQDCSAAVENLLLRATELGLGAVWCGVYPREERVKAFRELLGIPEHVVPFALVPVGYPAEHPVQVDRFKPERIHYEKW
>NC_021214.1|WP_004083200.1|401381_402044_-|endonuclease-III-domain-containing-protein
MRLTELYRKLLEIHGSVGKWWPGTPEEIVITAVLTQNTNWKNVERAMENIKNEVKGNNLLKELDSLPEEKVAELIRPAGFFNIKTKRLKELLKFLKEYNYNLSRLRDLPTHILRERLLKIKGIGKETADAILLYALEKPVFVVDSYTRRLLKRIFNIELNDYDEVQKLFMTHYPEDVRLYQEFHGLIVEHAKKFCSKTPKCGVCPLKKECCHVSQMNGFS
>NC_021214.1|WP_004083198.1|400055_401405_+|dihydrolipoyl-dehydrogenase
MYDAVIIGGGPGGYVCAIKLAQLGKKVALVEKDALGGTCTNRGCIPTKAMLTVSHLMDEMKEKASKYGLKVSGVEYDVAAIMKHVQKSVMMSRKGIEYLLKKNGVEVFKGTAVVENKNTVVVQETGEKLEAKNLVLAHGSVPSVFSPFDIDGVWTSDDVFNLKEFPKSLVIVGGGVIGVEFATFFGSFGVDVTIVEIAEHILPYEDSDVAEEVKKALKRKGVKILEKTKISSLSKVDDGFEVALENGETLKAEKVLLAAGRKPNIPEDVKALGVKIEKGVVTDSRMRTNVENVYAIGDIRSGIMLAHVAMYEGIVAAKNIAGEEEEMDYSAVPSIIFSSPEVASVGVREKDVNPEEVVISKFPVSANGRARTMLENIGFAKVIADKKDGTVLGMSIVSPSATDMIMEGVIAVKFRMKAEDLEKAIHPHPTLTETILGALEGVSGKPIHL
>NC_021214.1|WP_004083197.1|399674_400010_+|carboxymuconolactone-decarboxylase-family-protein
MAAKEKLEQIQKQLQEIIGKAPEIGKFAEYVHAAESPKALDTKTKELISLGIAVAVRCEPCIVWHAGAAVRAGATEEEILDTIKVAVCMGGGPALMYGLKAYEIALEFLGK
>NC_021214.1|WP_004083215.1|411584_412805_+|glycosyltransferase
MDVVLRERSIEEYRTIIGNEVDEIKKLAEPLKGKKVLHVNATAYGGGVAEILHNLVPLMRSVGLDARWRVIEAPDEFFNVTKKFHNTLQGADIEISEEEWNLYEEVCRKNAELIQDEELFVIHDSQPAAVRKFVDLNDRKWIWRCHIDLSTPNMKVWQKFSQYLEGYNRLVFHLEEYFPQGWKERSIAFPPSIDPLSEKNRDLDEDTIRKTLERLEIDPERPLITVVARFDPWKDLFSAIDVYRLVKKEIPEVQLAVVSAMAADDPEGWFFFEKVLRYAGTDEDIKFCTNLKGVGNKEVNAIQRATTVALHTATREGFGLVISEALYKRVPVVARPVGGVKIQVKHGENGYLAWEREDLAGYVVKLIKDEELRRKMGEKGRQTVVENFIITVHLKNYLKLFLDLLR
>NC_021214.1|WP_004083219.1|412809_413925_+|ROK-family-transcriptional-regulator
MPSPLLRRENKIKILRYILKNGKTTRNQLASNLNLAHSTLSYIIDELLDEGFLVFEEIKKKRGRPYQILSVNPEKFTAIGVKVGREEVRGVLFDARMNPLKEHRVQILSGMRNNDGYTRALRETIEQLRSENLLGVGICSSGIVKEGRVVVSHVMNVKDWDPRKVLKDLERILVMNDSDALCREISQRVNTDFLLVSYGVGIGASLWKDKKIHHIEMGHMLAASEGKCYCGQTGCLEYHSSEYAVLKSYLGKEIDFEDFITSEEEKYRQTIEELREKAREDFDSVKVHYEKAFKTFSVVLGNVIMGSGVSRVFFAGEGVVSEEMVKILEELVKVRFNRDFVGEVQFQVADANWMLGAARAVVDKYLPYIVK
>NC_021214.1|WP_004083223.1|413951_414689_-|hypothetical-protein
MVRIDAKGLHYKKLNDLIWEAVENGEEEIVLDNVCGQRYIGAGIRKKVKIEINGVPGNDLGVFMDGPEIIVNGNAQDGVGNTMNAGKIVVHGHAGDIIGYAMRGGHIYIKRNAGYRVGIHMKAYKENYPVVVIGGFARDFLGEYMAGGLLIVLGLEKDEDGNIAGNYVGTGMHGGEIFLRGTVEEHKLGKEVKIFQPTEEDINRIKPYVEEFCRLFDYDSEEILNEEFIILKPYTHRPYGRLYAY
>NC_021214.1|WP_004083225.1|414676_415954_-|NAD(P)/FAD-dependent-oxidoreductase
MRYVIVGSGPAGLNAIEAIREVDKEGEILLITAEKYVGYSRPLITYLLGRKVTEEKMYYRTEDYLREMRVDIKPATRVEKVIPEEKTVVTDSGEEIRYDKLLIATGGKPFVPNIEGLTGKKGVFTFTTWEDEEKVEKYIEENDVKEAVVLGGGLIGLKTTEALMELGVKVTIVELADRILSVTFDRKASEIITEALKKEGCSVITNDTVVKVNGDDTVSSVVLKSGKEIPTKLLVIAIGVKPNVEFLKDSGIEINRGIVVNEKMETNVEGVYAAGDCTEFYDLIDGQRKTIAIWPVAVAQGRVAGYNMAGKNVRYPGGIPMNSVELAGIPTISVGHSNVEDGGYEILTFEEGNTYKKMVLKDNRLVGAILVNDIDRAGIYTGLILQKLDVSSFKDRLLDENFGLVYLPKEFRKKMLEGEIKIWLE
>NC_021214.1|WP_004083227.1|415950_416406_-|4Fe-4S-dicluster-domain-containing-protein
MIAVRRILIREEYCMGCKLCEINCVAAQVGTGNLIKVYRYVPELPEPNVIVEEHDYVTFALQCRNCDDPSCLKACMTGAMHRDPKTGAIRVNQEKCVGCWMCVMACPFGVIRRNTKEKKVASKCDLCADRGTPGCVEGCPNEALVLVEVRE
>NC_021214.1|WP_004083229.1|416402_417926_-|4Fe-4S-dicluster-domain-containing-protein
MAKRKVPPEFVVERDDYKCIRCLACVRVCSYGANFYDENANRVYTENTKCVGCHFCEAICPTEAITVRKNDFDIRPLAHWTPEHLIGIMKQAETGGVLLTSMGNDRPYFSYFDRIVLNASQVTNPSIDPLREPMEIRTYIGRKEEKLEIEEDEDGTVKLKTEIAPQLKLEVPVMFTAMSYGSISLNAILSLARAARTVGTFFNTGEGGLPKELREFKDNMIVQVASGRFGVSADYLNAGSAVEIKIGQGAKPGIGGHLPGEKVTEPISETRMIPVGTDALSPAPHHDIYSIEDLRQLIYAIKEATRYEKPVGVKIAAVHNVAPIAAGAVRAGADYIVIDGIRGGTGAAPKITRDHVGIPIEFAVAVVDQRLREEGIRHMASIVVAGGIRNSADVIKAIALGADAVYIGTAALISLGCHLCQTCYLGKCNWGIATQDPKLTKRLNPEIGARRAANLLRAWAHEIKEILGGMGINAIESLRGNREVLRGVGLHEYELKLLGIKPAGEAW
>NC_021214.1|WP_004083231.1|417918_419052_-|glutamine-amidotransferase-family-protein
MSYDLPRLTPDKDFKVPSACGVSGIMNTSGKRFSGSVIVESMALMRERGNGLGAGYAAYGIYPELKDLYCFHMLYDSDLDKKNAEEYIKDHYEIIESEPIPTRKNPHIKEVHILWRYFLKPKFIPEDMSEEDFVVSTVMFINEKINGAFVMSSGKNMGVFKGVGFPEDIADFYRIDEYKGYIWTAHNRFPTNTVGWWGGAHPFGILDWTVVHNGEISSYGINRRFLEAYGYKCTLMTDTEVVAYLVDLFMRRFGYSPQLTAKILAAPLWKDIDLMPEEERKLYTALRMNYGGALLNGPFAIIVANNNMMMGLNDRIKLRPLVAATKDDFLYIASEESAIRVVCPEPDEVWAPKAGDPVVGVLKSARKTQVVLEGENG
>NC_021214.1|WP_004083233.1|419452_420130_+|response-regulator-transcription-factor
MNVRVLVVEDERDLADLITEALKKEMFTVDVCYDGEEGMYMALNEPFDVVILDIMLPVHDGWEILKSMRESGVNTPVLMLTALSDVEYRVKGLNMGADDYLPKPFDLRELIARVRALIRRKSESKSTKLVCGDLILDTATKKAYRGSKEIDLTKKEYQILEYLVMNKNRVVTKEELQEHLWSFDDEVFSDVLRSHIKNLRKKVDKGFKKKIIHTVRGIGYVARDE
>NC_021214.1|WP_004083236.1|420110_421328_+|HAMP-domain-containing-histidine-kinase
MLPVTSERKAFRKTQLIWTAVFTLSIVLIVAITVGAVFIVEKRRITTQFDGELRRTADLIERRLRAPGMMGMLRTFRGVDPLFVPRGEAFQFLLPSGEVFLEVGEQIGTPETPVEEGFSTEGNYRIFTKKIDLGDTTIFLRVGKDISDLIERSKRLLSMYLLVILFSAGGAAVFGYFVSSLALLPVRNAYNSLKRFSMDASHELKTPLSVLKTSLDVLKYREDLPDDVKNKLGIMEKNVEKMSKQINQLLLLVKSEGSLNSVVKERINLKDFLQQIVDEFKPKAESKGLELEIDCPEDLFLETEKDTLRVILENLVDNAVKFTEKGKVIVGARKEGRLTIYVQDTGPGIPKKEQKRIFERFYRISRNTEGSGLGLSIVKELASRLKAKVILESEEGKGSTFKLVF
>NC_021214.1|WP_004083238.1|421311_421866_-|thymidine-kinase
MSGKLTVITGPMYSGKTTELLSFVEIYKLGKKKVAVFKPKIDSRYHSTMIVSHSGNGVEAHVIERPEEMRKYIEEDTRGVFIDEVQFFNPSLFEVVKDLLDRGIDVFCAGLDLTHKQNPFETTALLLSLADTVIKKKAVCHRCGEYNATLTLKVAGGEEEIDVGGQEKYIAVCRDCYNTLKKRV

Crispr_ID: NC_021214_5

• CRISPR_ID: NC_021214_5
• CRISPR_location: 1428101-1428262
• CRISPR_type: Orphan
• Repeat_type: III-A
• Spacer_info: 2 spacers

Consensus repeat of NC_021214_5

Consensus_repeat	Method
GTTTCCATACCTCTAAGGAATTATTGAAACC	CRISPRCasFinder

spacers of NC_021214_5

>5.1|1428132|35|NC_021214|CRISPRCasFinder
TCTTGTGATGCCGGCGATGGGAAAGCCGAAAAACA
>5.2|1428198|34|NC_021214|CRISPRCasFinder
GAGCTTGTAGCAGACTACACTATTAAGAAGATGG

CRISPR arrays and Neighbor proteins around NC_021214_5

CRISPR arrays

The CRISPR arrays of NC_021214_5

>merge|NC_021214|5|1428101-1428262|CRISPRCasFinder
TTTTTCGTACATCTAAGGAAGTATTGAAACATCTTGTGATGCCGGCGATGGGAAAGCCGAAAAACAGTTTCCATACCTCTAAGGAATTATTGAAACCGAGCTTGTAGCAGACTACACTATTAAGAAGATGGGTTTCCATACCTCTAAGGAATTATTGAAACC

>NC_021214|5|5|1428101-1428262|CRISPRCasFinder
TTTTTCGTACATCTAAGGAAGTATTGAAACA	TCTTGTGATGCCGGCGATGGGAAAGCCGAAAAACA
GTTTCCATACCTCTAAGGAATTATTGAAACC	GAGCTTGTAGCAGACTACACTATTAAGAAGATGG
GTTTCCATACCTCTAAGGAATTATTGAAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021214.1|WP_004081631.1|1417379_1417532_-|hypothetical-protein	unknown	unknown	unknown
NC_021214.1|WP_004081659.1|1432775_1433393_-|CDP-alcohol-phosphatidyltransferase-family-protein	unknown	unknown	gnl|CDD|223632
NC_021214.1|WP_004081637.1|1421655_1422852_-|histidine-kinase	unknown	unknown	gnl|CDD|376570
NC_021214.1|WP_004081643.1|1426365_1427337_+|endo-alpha-1,4-polygalactosaminidase	unknown	unknown	gnl|CDD|273582
NC_021214.1|WP_004081662.1|1434152_1435301_-|inositol-3-phosphate-synthase	unknown	unknown	gnl|CDD|224180
NC_021214.1|WP_004081666.1|1435782_1437348_+|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|226972
NC_021214.1|WP_004081644.1|1427314_1428052_+|DUF3492-domain-containing-protein	unknown	unknown	gnl|CDD|273041
NC_021214.1|WP_004081661.1|1433386_1434112_-|nucleotidyltransferase	unknown	unknown	gnl|CDD|224134
NC_021214.1|WP_004081635.1|1420853_1421690_-|hypothetical-protein	unknown	unknown	unknown
NC_021214.1|WP_012311059.1|1435562_1435790_+|NAD(P)H-dependent-oxidoreductase-subunit-E	unknown	unknown	gnl|CDD|224817
NC_021214.1|WP_004081639.1|1422848_1424225_-|exopolysaccharide-Pel-transporter-PelG	unknown	unknown	gnl|CDD|226717
NC_021214.1|WP_004081652.1|1430131_1430902_-|inositol-monophosphatase	unknown	unknown	gnl|CDD|223559
NC_021214.1|WP_004081634.1|1419514_1420921_+|GT4-family-glycosyltransferase-PelF	unknown	unknown	gnl|CDD|340841
NC_021214.1|WP_004081633.1|1418655_1419426_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|130314
NC_021214.1|WP_004081668.1|1437334_1438474_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NC_021214.1|WP_004081657.1|1432011_1432743_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223473
NC_021214.1|WP_004081649.1|1428831_1430130_-|glycoside-hydrolase-family-32-protein	unknown	unknown	gnl|CDD|224536
NC_021214.1|WP_004081642.1|1424214_1426365_-|DUF2194-domain-containing-protein	unknown	unknown	gnl|CDD|378327
NC_021214.1|WP_004081632.1|1417667_1418651_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213232
NC_021214.1|WP_004081655.1|1431058_1432015_-|SufD-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl|CDD|223791

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021214.1|WP_004081659.1|1432775_1433393_-|CDP-alcohol-phosphatidyltransferase-family-protein	gnl|CDD|223632	COG0558, PgsA, Phosphatidylglycerophosphate synthase [Lipid metabolism].	1.7615e-17
NC_021214.1|WP_004081662.1|1434152_1435301_-|inositol-3-phosphate-synthase	gnl|CDD|224180	COG1260, INO1, Myo-inositol-1-phosphate synthase [Lipid metabolism].	6.56499e-158
NC_021214.1|WP_004081637.1|1421655_1422852_-|histidine-kinase	gnl|CDD|376570	pfam01590, GAF, GAF domain. This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl cyclases, phytochromes, FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP, respectively, these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. Here too, cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum, while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54.	0.00115055
NC_021214.1|WP_004081643.1|1426365_1427337_+|endo-alpha-1,4-polygalactosaminidase	gnl|CDD|273582	TIGR01370, Uncharacterized_protein_DR_0705, extracellular protein. Original assignment of this protein family as cysteinyl-tRNA synthetase is controversial, supported by but challenged by and by subsequent discovery of the actual mechanism for synthesizing Cys-tRNA in species where a direct Cys--tRNA ligase was not found. Lingering legacy annotations of members of this family probably should be removed. Evidence against the role includes a signal peptide. This family as been renamed "extracellular protein" to facilitate correction. Members of this family occur in Deinococcus radiodurans (bacterial) and Methanococcus jannaschii (archaeal). A number of homologous but more distantly related proteins are annotated as alpha-1,4 polygalactosaminidases. The function remains unknown. [Unknown function, General].	2.26575e-177
NC_021214.1|WP_004081666.1|1435782_1437348_+|4Fe-4S-binding-protein	gnl|CDD|226972	COG4624, COG4624, Iron only hydrogenase large subunit, C-terminal domain [General function prediction only].	1.86663e-98
NC_021214.1|WP_004081644.1|1427314_1428052_+|DUF3492-domain-containing-protein	gnl|CDD|273041	TIGR00376, DNA-binding_protein_SMUBP-2, DNA helicase, putative. The gene product may represent a DNA helicase. Eukaryotic members of this family have been characterized as binding certain single-stranded G-rich DNA sequences (GGGGT and GGGCT). A number of related proteins are characterized as helicases. [DNA metabolism, DNA replication, recombination, and repair].	1.02696e-60
NC_021214.1|WP_004081661.1|1433386_1434112_-|nucleotidyltransferase	gnl|CDD|224134	COG1213, COG1213, Predicted sugar nucleotidyltransferases [Cell envelope biogenesis, outer membrane].	4.74777e-35
NC_021214.1|WP_012311059.1|1435562_1435790_+|NAD(P)H-dependent-oxidoreductase-subunit-E	gnl|CDD|224817	COG1905, NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit [Energy production and conversion].	4.7176e-24
NC_021214.1|WP_004081639.1|1422848_1424225_-|exopolysaccharide-Pel-transporter-PelG	gnl|CDD|226717	COG4267, COG4267, Predicted membrane protein [Function unknown].	1.16553e-176
NC_021214.1|WP_004081652.1|1430131_1430902_-|inositol-monophosphatase	gnl|CDD|223559	COG0483, SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism].	5.79825e-88
NC_021214.1|WP_004081634.1|1419514_1420921_+|GT4-family-glycosyltransferase-PelF	gnl|CDD|340841	cd03813, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.	0
NC_021214.1|WP_004081633.1|1418655_1419426_+|ABC-transporter-permease	gnl|CDD|130314	TIGR01247, drrB, daunorubicin resistance ABC transporter membrane protein. This model describes daunorubicin resistance ABC transporter, membrane associated protein in bacteria and archaea. The protein associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	2.65161e-87
NC_021214.1|WP_004081668.1|1437334_1438474_+|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	4.41959e-08
NC_021214.1|WP_004081657.1|1432011_1432743_-|ABC-transporter-ATP-binding-protein	gnl|CDD|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	2.1905e-98
NC_021214.1|WP_004081649.1|1428831_1430130_-|glycoside-hydrolase-family-32-protein	gnl|CDD|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	7.36092e-166
NC_021214.1|WP_004081642.1|1424214_1426365_-|DUF2194-domain-containing-protein	gnl|CDD|378327	pfam09960, DUF2194, Uncharacterized protein conserved in bacteria (DUF2194). This domain, found in various hypothetical bacterial proteins, has no known function.	1.48438e-145
NC_021214.1|WP_004081632.1|1417667_1418651_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213232	cd03265, ABC_DrrA, Daunorubicin/doxorubicin resistance ATP-binding protein. DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	3.89493e-150
NC_021214.1|WP_004081655.1|1431058_1432015_-|SufD-family-Fe-S-cluster-assembly-protein	gnl|CDD|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	5.79838e-71

Protein sequences

>NC_021214.1|WP_004081644.1|1427314_1428052_+|DUF3492-domain-containing-protein
MRVGLIAEGTYPYITGGVSSWIQTLISNLPEFEFEIYHLRPDSKKREVRYKIPKNVVRIHEVNIFGDFDPEIPEEANLSALTEITKAIVLSPKNVLVFIDTKNRSDRFERQRKDSPSRENPLEAQIVKEVVEKLLSMGVKEDWIGIITPYDDQVNLIRELIEAKVEVHSVDGFQGREKEVIIISFVRSNKNGEIGFLEDLRRLNVSLTRAKRKLIATGDSSTLSVHPTYRRFVEFVKKKGTYVIF
>NC_021214.1|WP_004081643.1|1426365_1427337_+|endo-alpha-1,4-polygalactosaminidase
MSHLKNILFIIIVSLFFISSCSTVMSTEGWFMPFDNWLYQLQNADPVEISSSGFEIAVIDYSKDGSESGEYSPEEIKIMVDAGVVPVAYVNIGQAEDYRFYWKESWYTNTPEWLGEEDPAWPGNYFVKYWYNEWKEIVFSYLDRVIDQGFKGIYLDRIDSFEYWAQEGVISRRSAARKMINFVLEIAEYVRERKPDMLIIPQNGENILDFDDGQLASTVSGWAVENLFYLKTIPLEENETKSRLEYLIRLNRKGKFILSVDYVDDGSDSFENISRILDYYEKAKRNGCIPYAARSDLELDEMNVIEGIQPPEALKDYESRTYR
>NC_021214.1|WP_004081642.1|1424214_1426365_-|DUF2194-domain-containing-protein
MRKFLLLILVLLAFPFFSKTLLLYKGSEGGYGYNILSWLAPEPEVLGEDYEFVDVEKSLPDFEDYDFVITCYYSSSMPGAKKYLKKLVDFLLNGGKLFIINNLGAFEDSSGDNPSLSDINTLLNLLGVSFRYGWRQETVFSYEIEDGYLIKLPSFPVKKAFDGFEVFSSNVKIVSYAVTKKGKHPVIFYGPFGGMALFDHAFNENGEPVVDLRKIVMDIVGGYRENKVLMLDENHHIRKMFEYALFEVDSSRSGVLQKYRAIVIPDVSFLEEKEIKSYLENGGVVILVGSGTHYIQGEVVLEKENLYIPQDITVGERKVGYIPAPENAKAFITISGTPVSWMEKREKGAFVFFPEDLLEKWSRGILFNEFLEASDFVISPMVNAFSVFLDDFPLPAYGIEYDILGTTDEIFYYKIWWRDMKELCEDFSIKPITALVTSYEQKTDYNGFFEFLEKDSSLKVLKNLIEDERVDTGIHGYNHVPPKSENWDLEELGKAYKSLRIFLSQLSSSYEPVAFVAPNNEIDQAGIEVLKSVFPTIKVIGTAYSLKDSTGEFTLLDDALILPRTTSGCYPLQRLLMETVSTLLNLGTYHHFSHPDDVISLDRNPERYSWNEMFDQLRSFFRIMKENYPWLRNMDSKELYNTFKDYFENKPRILYHDKKIVIVLPRTAELPRYFFLKAKGDVNVHGGVILFRDKDLCVVEMREYKMEISEVIEDGR
>NC_021214.1|WP_004081639.1|1422848_1424225_-|exopolysaccharide-Pel-transporter-PelG
MAGKSFDLLFSRNNLFSDVLAFFYSTFVYFAPWLVVLFYIIWSSRWFSPSPFFLSVLSYSLIFSMIIAGGMSFLISRFLANCIYSRDQRKIYESYIGAVLLVFSVSLVIGLIFFAVNNQYSLVQKILACYTFVGFSLVWILMQFASVTEKESLAVLAFAGGIVVSVLLARFWDISMEEKLLLTLDIGIGLIIFMLNFLILSYLRSSIRIGFDFLLLTRKHPQLLFIGYFYYLSIWIDNFIAWKVKGIEIAPGFFMSPEYDIPKFMASLFFIPSLVVFNLSMETVFQRNYKGLMQSIVSDKPMRVISENLKKLSLSLRHAFSNMFALNMVAMISCFLLRDSLRLWFNLSESFNRIFVWDVVGVSMNIAFMSLLVASLHFEYYGIALEGTALVLTSNMILSVFFIENIPGLSFAVAFSGGFLYLLLRFKSKDFLYEVYTKQPLGLEKVKKTSWKPKEMIR
>NC_021214.1|WP_004081637.1|1421655_1422852_-|histidine-kinase
MKPRKKSWFVEVLISYGIVFLFDYLYKTDVFKESFLNFYWIPLLIFCVRYDLVVHVFSSILFFTFIVVSKFLSEEGLNFSSDFALANSIMLVISTVLSLINEVRVKNMERLSLELAYRNEDVSRLEEEVRKLKKQINSLEQKLFYESTGISSLLIELREIFTEDFEKFAQRFVEIVSEYFDVKRMYVYRYKDGFLRLAAGIGRPELGFSLKKGVSLVVDKALQEGVGRILDVVDQVKSSNEPWLAVRIGDGENILGVITVEETATDNLELVEEYLTALATWIHIVMRKLEFEKYEKYRLKDGTFPADFYETEKNRLKVLEAQHGIPFIEVCVRIKREELGKLLKILRRNDLATKMSEDGEYLLLKLLFPLCDEIGFNIIKKRLESEISEVEIVDCESH
>NC_021214.1|WP_004081635.1|1420853_1421690_-|hypothetical-protein
MKSKLWIVNLINFALGVLNIGLLLQGENPFFIMILCLNLVISFLVNRDVSQIVIAIMTYPLGLVVPLKKKKLRFEGVGKPQKVERINLMKRSFKEAIFFGQDEDKKRSILRLSEDVEKGKVPPERLISASKRLMKNSGVDVGLYTTESIERVEKSFEKEEEILLNIENLDDKSEELYERVWDYLEADFVSGKLKEYYRFLLLDRLKLLGKDERYFIMKYRVERNLEVLWEGLKQTRSPLIYRTLLFELLKRRNYPELRQLKLFFSKSEKDKDSGTSQS
>NC_021214.1|WP_004081634.1|1419514_1420921_+|GT4-family-glycosyltransferase-PelF
MKIGLILEGTYPYVTGGVSNWVHTLLTNLPEFEFEIYHLKAVTEPQTIKYKIPENVTAVHELNIFGDFESDSSQKANLESLERIVSQLSIERDIRSIVSFAIDFIRENAGKNVRKMLKTKGFWNILLKIYEEFFSERGLTEFYWMIMNLFLPVVNVLQFVPNRCDLFHVPSTGYASLVGMNGKFVHDVPLVITEHGIYHKEREREIILSTWVPDAYKPMWIELFRIISMIAYRVSDALTTLYRKNQIYQLELGADPEKMFIIPNGINVEEYDLPPEKHEGFVVGFVGRVARIKDLKTAIRAISIVKEVVGEKLTFLIIGPVDAEDYLAECKRLVRVLRLEDTVEFLGPQNVKEYYPKFDLLLLSSVSEGQPLVILEAMAAGVPIVATDVGACRDIIYDKDGQCGIVVPPKDHLSMSKAIIKLYEDKELRDTFSKNAKKVVQKYRVETMIEKYRNLYLSLTSKKTVSTV
>NC_021214.1|WP_004081633.1|1418655_1419426_+|ABC-transporter-permease
MAAFVTMIYRQFMRFLRSRSRVIGMIINPLIWIIFFGLGWSKVFDNPWAKMMFGGVDYLTYLAPGIFAMTVFNMSFISGVSLIWDKQFGFFKEVLVAPSSRRLSITGRIVGDAIVTVLQGLIILVFNYFLAESLKISGLLPALAVGFLMSVTIASFGIALALKMESTEGFQMIMMTLMMPLVFLSGAMYPIDSMPNWMKALAYINPLTYAVDASRGYLVGEKVMKFSFGLDWGILSILMLVGLILAMESFERARIS
>NC_021214.1|WP_004081632.1|1417667_1418651_+|ATP-binding-cassette-domain-containing-protein
MEDIIVVENLVKKFGDFEAVKGVSFSVKKGEIFAFLGPNGAGKTTTIHMLTTLLKPTSGKAWVAGHDVLKEPREVRRKIGIVFQDQSLDRELTAYENMYIHGKIYGYGGEKLKKRILELLEFVELLEFKDKPVKTFSGGMARRLEIARSLIHEPEVLFLDEPTIGLDPHTRAHMWEYISKMKKEHNMTIFLTTHYMDEAEQLADRVAIIDHGKIIALGTPTELKRMVGKEIIYVRFSEAVECLEGDFIESCRKLPDGRLELNVEDSGRAIPKIFELAQQKGLKIEEITYHKPTLNDVFLHLTGRELREEGPENSFKTMARMRMRMRR
>NC_021214.1|WP_004081631.1|1417379_1417532_-|hypothetical-protein
MERVRDFFVLLFCVLLFIYEFLALNVRIMFRSIKKKRSRETTPGFKFPVL
>NC_021214.1|WP_004081649.1|1428831_1430130_-|glycoside-hydrolase-family-32-protein
MFKPNYHFFPITGWMNDPNGLIFWKGKYHMFYQYNPRKPEWGNICWGHAVSDDLVHWRHLPVALYPDDETHGVFSGSAVEKDGKMFLVYTYYRDPTHNKGEKETQCVAMSENGLDFVKYDGNPVISKPPEEGTHAFRDPKVNRSNGEWRMVLGSGKDEKIGRVLLYTSDDLFHWKYEGVIFEDETTKEIECPDLVRIGEKDILIYSITSTNSVLFSMGELKEGKLNVEKRGLLDHGTDFYAAQTFFGTDRVVVIGWLQSWLRTGLYPTKREGWNGVMSLPRELYVENNELKVKPVDELLALRKRKVFETAKSGTFLLDVKENSYEIVCEFSGEIELRMGNESEEVVITKSRDELIVDTTRSGVSGGEVRKSTVEDEATNRIRAFLDSCSVEFFFNDSIAFSFRIHPENVYNILSVKSNQVKLEVFELENIWL
>NC_021214.1|WP_004081652.1|1430131_1430902_-|inositol-monophosphatase
MDRLDFSIKLLRKVGHLLMIHWGRVDNVEKKTGFKDIVTEIDREAQRMIVDEIRKFFPDENIMAEEGIFEKGDRLWIIDPIDGTINFVHGLPNFSISLAYVENGEVKLGVVHAPALNETLYAEEGSGAFFNGERIRVSENASLEECVGSTGSYVDFTGKFIERMEKRTRRIRILGSAALNAAYVGAGRVDFFVTWRINPWDIAAGLIIVKEAGGMVTDFSGKEANAFSKNFIFSNGLIHDEVVKVVNEVVEEIGGK
>NC_021214.1|WP_004081655.1|1431058_1432015_-|SufD-family-Fe-S-cluster-assembly-protein
MIVKDYRREFEALAKAYEKAGGDVSKFLDRRIASIIISGDKVIGLNGVEGVELTPYRIENGVQVDMRIKEGVVVEYPVHVCTGYLEKKGLQRVVFNIRLEKNAKAIFVAHCVFPWTEDFTHDALMNVELEEGAWMEYHDEHTHSETGSINLITRSIARVGERAVYRNTFTLVKTRIGTLRVFMDASLEKDAVGELYTKVKAVEDDDVEVKEILRLNGMGARGLAKTNAVAIDRAKVSVVNEVYGNAPHTRGHVECLEIAKGDGVDVRALPVLVVKNDSSELTHEASIGRVNAKQLETLMAKGLTEEEATEMIIKGILT
>NC_021214.1|WP_004081657.1|1432011_1432743_-|ABC-transporter-ATP-binding-protein
MLELIDVWYEVEGKAILKGINARFEKQRVYSILGTNGAGKSTLAYLIMGLEGYRPTRGKILLDGEDITDLSVTERAKRGITLMWQEPARFTGIKIRDYLTLGGRRKVSKEELERVLELVGLNPALYLERNVDEKLSGGERKRVELASILLMKPRYTILDEPDSGIDIMSLEMIEKVLSELVSAGGSVILVTHREEIALESDYAFLICHGSILKEGNPSEIVQFYKNSCDRCDHPNEPSGEMIV
>NC_021214.1|WP_004081659.1|1432775_1433393_-|CDP-alcohol-phosphatidyltransferase-family-protein
MLRKSTDGWISSLINRRFSSRITNLILEKNWQITPNQMSFISFLVGVLAFPFYLLKLPWIAGILVQVSSVLDGVDGELARARNMSSNWGAFFDTMLDRFVDILAVLGLSLYGCLKDGPSLSLLLWSVLAVSGSLMVSYLHSVGKVFGTHPALVGKLSGFASRDVRLFVVFVFSLFGMHLPALVVISILSYVYTTGKFVELLVLNR
>NC_021214.1|WP_004081661.1|1433386_1434112_-|nucleotidyltransferase
MREAIVLASGAGKRLRSVTGDVPKVFYRFDGCELVKYPMISLMKNGVERFVLVVSEGYRDLGEKVLNDLGVEGIVVENKKVELGNAYSFFLSEPYVESEKFFLSCGDSLFPPEALKSAFSEDEFHIKLGVSKRSDLIDPEEASKVLVNEDRIVKIGKRIDEYNYFDTGVFVMTKKVYSLKESFSWTEEISLYHVLQKAVDTGMIVKVFDFGNALWTEIDSPEDLNEKVYELMKKIKEGVAC
>NC_021214.1|WP_004081662.1|1434152_1435301_-|inositol-3-phosphate-synthase
MVKVLILGQGYVASTFVAGLEKLRKGEIEPYGVPLARELPIGFEDIKIVGSYDVDRAKIGKKLSEVVKQYWNDVDSLTSDPEIRKGVHLGSVRNLPIEAEGLEDSMTLKEAVDTLVKEWTELDPDVIVNTCTTEAFVPFGNKEDLLKAIENNDKERLTATQVYAYAAALYANKRGGAAFVNVIPTFIANDPAFVELAKENNLVVFGDDGATGATPFTADVLSHLAQRNRYVKDVAQFNIGGNMDFLALTDDGKNKSKEFTKSSIVKDILGYDAPHYIKPTGYLEPLGDKKFIAIHIEYVSFNGATDELMINGRINDSPALGGLLVDLVRLGKIALDRKEFGTVYPVNAFYMKNPGPAEEKNIPRIIAYEKMRIWAGLKPKWL
>NC_021214.1|WP_012311059.1|1435562_1435790_+|NAD(P)H-dependent-oxidoreductase-subunit-E
MIVRVCMGSSCHLKGSYEVVRRFQELQKKYNFKLYGSLCFGNCSQGVCVEIDGRLFSRVTPENAEEILKKVLQNG
>NC_021214.1|WP_004081666.1|1435782_1437348_+|4Fe-4S-binding-protein
MAELIFSRETDCRYCYKCLRNCPVKAISFKSGKSTVLEEECVFCGSCLDICPQNARSYRKDVERFLSLSEPFLVSIAPSFFAYFENPLKVIGVLKEMGAVVVQETAVGAEIVSRRYEEVFEKHSGPFITTACPVVVNLAEKHFPNVLKYFAPVDSPLMTHAKFLKTRYGDFPIVFVGPCIAKKSESDLVDVALTFEELEEILEEREGKEALPDGPYPDRARFYPTTDGIGYTVSVPWEKKLVVEGVENLMRVFSRIDEYKSVFIEASACYGSCLNGPVMKKKSNGKERLLEWQKKLPKEPKVNHLKIDTFRSYRNKSRNVEVPEEEIKKVLVSIGKDDPSKELNCGACGYDSCREKARAVVLGKAEKEMCFVYLLDLVKSSSYRVVEESPNAVFVLKDEKVIYRNRVAGELIQNYPEILERAKGSVGETLTIEGKRFFFVKEFSLEDGEEVIMLVDITQEKLKDEELDKVKRETLRKVEEMLNKQMRIAQEIAGILGESIAETKSSFMELKMFMEGENADL
>NC_021214.1|WP_004081668.1|1437334_1438474_+|SpoIIE-family-protein-phosphatase
MLTCDVFFASKNKKGEEVCGDSIKVKRESEKIVVSVSDGLGSGIKASILSTLTATIASTMLMNGLPVTDVFRTILATLPICRVRKISYSNLCSVVCDFKNNTCTVVEYEFPVVMLFKGERRVFPEKQGLEIEGKKVFVWQFRSEAGTLLLLATDGLSQAGMGTDLFPLGFGVENIEKEMKHLLKNHVSPENIVRHFVKLAEKLDQEVRGDDTLVACLNFREKRILNLFVGPPEDRKKDEEYVRTFLSLPGKKIVCGGTTGQIFERVTGKKVEIDLYTLSENSPPVGYMEGIDLMTEGIVTLTQVFRYLEGQSEELGYGAKFIVKSLLEADEINFFVGRAINPAHQNPLFSHDISLKFRLVKDIAQILREKGKIVNVQYC

Crispr_ID: NC_021214_6

• CRISPR_ID: NC_021214_6
• CRISPR_location: 1519929-1520491
• CRISPR_type: Orphan
• Repeat_type: III-A
• Spacer_info: 8 spacers

Consensus repeat of NC_021214_6

Consensus_repeat	Method
GTTTCAATACTTCCTTAGAGGTATGGAAAC	PILER-CR
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CRISPRCasFinder
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CRT

spacers of NC_021214_6

>6.1|1519959|41|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TCAGTTCCCCTGCTTTCTGGATTGTTAAGCGAGGATCTTCC
>6.2|1520030|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TCATACTCATCCCTCCCTCAAACCTTCAAATTGTCC
>6.3|1520096|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT
CCTGACGGCAAAATCGTTTTCCGCACACGCATTGA
>6.4|1520161|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
ATCTTTCTAATCTTATAGGTTAGAAACGGCTTCTAA
>6.5|1520227|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
AGGACTTCTTGTTGTAGTTTGCGGAACATATCATAC
>6.6|1520293|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
GAATTGCTCTTGTACGAAAAGCTCGAATCCTTCGTC
>6.7|1520359|36|NC_021214|PILER-CR,CRISPRCasFinder,CRT
TCAGAGGAGACTACGACCTTTTCGAATACGCCGACA
>6.8|1520425|37|NC_021214|CRISPRCasFinder,CRT
GCTCCTCCCTGTAGTCGTGGTCCACGATATTGAGCCA

CRISPR arrays and Neighbor proteins around NC_021214_6

CRISPR arrays

The CRISPR arrays of NC_021214_6

>merge|NC_021214|6|1519929-1520491|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATACTTCCTTAGAGGTATGGAAACTCAGTTCCCCTGCTTTCTGGATTGTTAAGCGAGGATCTTCCGTTTCAATACTTCCTTAGAGGTATGGAAACTCATACTCATCCCTCCCTCAAACCTTCAAATTGTCCGTTTCAATACTTCCTTAGAGGTATGGAAACCCTGACGGCAAAATCGTTTTCCGCACACGCATTGAGTTTCAATACTTCCTTAGAGGTATGGAAACATCTTTCTAATCTTATAGGTTAGAAACGGCTTCTAAGTTTCAATACTTCCTTAGAGGTATGGAAACAGGACTTCTTGTTGTAGTTTGCGGAACATATCATACGTTTCAATACTTCCTTAGAGGTATGGAAACGAATTGCTCTTGTACGAAAAGCTCGAATCCTTCGTCGTTTCAATACTTCCTTAGAGGTATGGAAACTCAGAGGAGACTACGACCTTTTCGAATACGCCGACAGTTTCAATAATTCCTTAGAGGTATGGAAACGCTCCTCCCTGTAGTCGTGGTCCACGATATTGAGCCAGTTTCAATGCGTCTTCAGAGGTACAAGAAC

>NC_021214|6|5|1519929-1520424|PILER-CR
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCAGTTCCCCTGCTTTCTGGATTGTTAAGCGAGGATCTTCC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCATACTCATCCCTCCCTCAAACCTTCAAATTGTCC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CCTGACGGCAAAATCGTTTTCCGCACACGCATTGA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATCTTTCTAATCTTATAGGTTAGAAACGGCTTCTAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	AGGACTTCTTGTTGTAGTTTGCGGAACATATCATAC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	GAATTGCTCTTGTACGAAAAGCTCGAATCCTTCGTC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCAGAGGAGACTACGACCTTTTCGAATACGCCGACA
GTTTCAATAATTCCTTAGAGGTATGGAAAC

>NC_021214|6|6|1519929-1520491|CRISPRCasFinder
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCAGTTCCCCTGCTTTCTGGATTGTTAAGCGAGGATCTTCC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCATACTCATCCCTCCCTCAAACCTTCAAATTGTCC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CCTGACGGCAAAATCGTTTTCCGCACACGCATTGA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATCTTTCTAATCTTATAGGTTAGAAACGGCTTCTAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	AGGACTTCTTGTTGTAGTTTGCGGAACATATCATAC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	GAATTGCTCTTGTACGAAAAGCTCGAATCCTTCGTC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCAGAGGAGACTACGACCTTTTCGAATACGCCGACA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GCTCCTCCCTGTAGTCGTGGTCCACGATATTGAGCCA
GTTTCAATGCGTCTTCAGAGGTACAAGAAC

>NC_021214|6|5|1519929-1520491|CRT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCAGTTCCCCTGCTTTCTGGATTGTTAAGCGAGGATCTTCC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCATACTCATCCCTCCCTCAAACCTTCAAATTGTCC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	CCTGACGGCAAAATCGTTTTCCGCACACGCATTGA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	ATCTTTCTAATCTTATAGGTTAGAAACGGCTTCTAA
GTTTCAATACTTCCTTAGAGGTATGGAAAC	AGGACTTCTTGTTGTAGTTTGCGGAACATATCATAC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	GAATTGCTCTTGTACGAAAAGCTCGAATCCTTCGTC
GTTTCAATACTTCCTTAGAGGTATGGAAAC	TCAGAGGAGACTACGACCTTTTCGAATACGCCGACA
GTTTCAATAATTCCTTAGAGGTATGGAAAC	GCTCCTCCCTGTAGTCGTGGTCCACGATATTGAGCCA
GTTTCAATGCGTCTTCAGAGGTACAAGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021214.1|WP_004081907.1|1526652_1527969_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223717
NC_021214.1|WP_004081893.1|1522343_1522781_+|ferritin	unknown	unknown	gnl|CDD|224548
NC_021214.1|WP_004081875.1|1515090_1515792_-|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	unknown	unknown	gnl|CDD|132571
NC_021214.1|WP_004081891.1|1521399_1522224_+|endoglucanase	unknown	unknown	gnl|CDD|366751
NC_021214.1|WP_004081902.1|1524789_1525647_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl|CDD|224997
NC_021214.1|WP_004081884.1|1518024_1519002_-|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|237845
NC_021214.1|WP_004081895.1|1522742_1523165_-|RrF2-family-transcriptional-regulator	unknown	unknown	gnl|CDD|273242
NC_021214.1|WP_004081904.1|1525639_1526656_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl|CDD|224936
NC_021214.1|WP_004081900.1|1524067_1524688_+|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NC_021214.1|WP_004081868.1|1511625_1512699_-|amidohydrolase	unknown	unknown	gnl|CDD|349882
NC_021214.1|WP_004081897.1|1523192_1524062_+|1,4-dihydroxy-2-naphthoate-octaprenyltransferase	unknown	unknown	gnl|CDD|224491
NC_021214.1|WP_004081873.1|1513869_1515075_-|aspartate-kinase	unknown	unknown	gnl|CDD|235843
NC_021214.1|WP_004081870.1|1512699_1513860_-|diaminopimelate-decarboxylase	unknown	unknown	gnl|CDD|273415
NC_021214.1|WP_004081877.1|1515793_1516444_-|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl|CDD|223366
NC_021214.1|WP_004081864.1|1510811_1511204_-|hypothetical-protein	unknown	unknown	unknown
NC_021214.1|WP_004081866.1|1511200_1511611_-|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NC_021214.1|WP_010865354.1|1520626_1521403_+|endoglucanase	unknown	unknown	gnl|CDD|366751
NC_021214.1|WP_004081879.1|1516440_1517325_-|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl|CDD|235107
NC_021214.1|WP_004081881.1|1517309_1518020_-|diaminopimelate-epimerase	unknown	unknown	gnl|CDD|223331
NC_021214.1|WP_004081910.1|1527975_1528254_+|ferredoxin-family-protein	unknown	unknown	gnl|CDD|225289

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021214.1|WP_004081907.1|1526652_1527969_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	4.11584e-92
NC_021214.1|WP_004081893.1|1522343_1522781_+|ferritin	gnl|CDD|224548	COG1633, COG1633, Uncharacterized conserved protein [Function unknown].	3.95136e-28
NC_021214.1|WP_004081875.1|1515090_1515792_-|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	gnl|CDD|132571	TIGR03532, DapD_Ac, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase. This enzyme is part of the diaminopimelate pathway of lysine biosynthesis. Alternate name: tetrahydrodipicolinate N-acetyltransferase. Note that IUBMB lists this alternate name as the accepted name. Unfortunately, the related succinyl transferase acting on the same substrate (EC:2.3.1.117, TIGR00695) uses the opposite standard. We have decided to give these two enzymes names which more clearly indicated that they act on the same substrate.	1.0053e-119
NC_021214.1|WP_004081891.1|1521399_1522224_+|endoglucanase	gnl|CDD|366751	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12.	1.64563e-27
NC_021214.1|WP_004081902.1|1524789_1525647_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl|CDD|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	6.23927e-96
NC_021214.1|WP_004081884.1|1518024_1519002_-|aspartate-semialdehyde-dehydrogenase	gnl|CDD|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	1.72306e-151
NC_021214.1|WP_004081895.1|1522742_1523165_-|RrF2-family-transcriptional-regulator	gnl|CDD|273242	TIGR00738, Putative_HTH-type_transcriptional_regulator, Rrf2 family protein. This model represents a superfamily of probable transcriptional regulators. One member, RRF2 of Desulfovibrio vulgaris is an apparent regulatory protein experimentally (MEDLINE:97293189). The N-terminal region appears related to the DNA-binding biotin repressor region of the BirA bifunctional according to results after three rounds of PSI-BLAST with a fairly high stringency. [Unknown function, General].	4.37809e-49
NC_021214.1|WP_004081904.1|1525639_1526656_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl|CDD|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	3.69217e-138
NC_021214.1|WP_004081900.1|1524067_1524688_+|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	4.10698e-10
NC_021214.1|WP_004081868.1|1511625_1512699_-|amidohydrolase	gnl|CDD|349882	cd03886, M20_Acy1, M20 Peptidase Aminoacylase 1 family. Peptidase M20 family, Aminoacylase 1 (ACY1; hippuricase; acylase I; amido acid deacylase; IAA-amino acid hydrolase; dehydropeptidase II; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14) subfamily. ACY1 is the most abundant of the aminoacylases, a class of zinc binding homodimeric enzymes involved in the hydrolysis of N-acetylated proteins. It is encoded by the aminoacylase 1 gene (Acy1) on chromosome 3p21 that comprises 15 exons. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity; substrates include indoleacetic acid (IAA) N-conjugates of amino acids, N-acetyl-L-amino acids and aminobenzoylglutamate. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). ACY1 appears to physically interact with Sphingosine kinase type 1 (SphK1) and may influence its physiological functions; SphK1 and its product sphingosine-1-phosphate have been shown to promote cell growth and inhibit apoptosis of tumor cells. Strong expression of the human gene and its mouse ortholog Acy1 in brain, liver, and kidney, suggest a role of the enzyme in amino acid metabolism of these organs. Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D), resulting in a metabolic disorder manifesting encephalopathy and psychomotor delay.	1.87479e-141
NC_021214.1|WP_004081873.1|1513869_1515075_-|aspartate-kinase	gnl|CDD|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
NC_021214.1|WP_004081870.1|1512699_1513860_-|diaminopimelate-decarboxylase	gnl|CDD|273415	TIGR01048, Diaminopimelate_decarboxylase, diaminopimelate decarboxylase. This family consists of diaminopimelate decarboxylase, an enzyme which catalyzes the conversion of diaminopimelic acid into lysine during the last step of lysine biosynthesis. [Amino acid biosynthesis, Aspartate family].	0
NC_021214.1|WP_004081877.1|1515793_1516444_-|4-hydroxy-tetrahydrodipicolinate-reductase	gnl|CDD|223366	COG0289, DapB, Dihydrodipicolinate reductase [Amino acid transport and metabolism].	1.28517e-90
NC_021214.1|WP_004081897.1|1523192_1524062_+|1,4-dihydroxy-2-naphthoate-octaprenyltransferase	gnl|CDD|224491	COG1575, MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism].	2.62463e-94
NC_021214.1|WP_004081866.1|1511200_1511611_-|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	7.64994e-34
NC_021214.1|WP_010865354.1|1520626_1521403_+|endoglucanase	gnl|CDD|366751	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12.	9.24668e-75
NC_021214.1|WP_004081879.1|1516440_1517325_-|4-hydroxy-tetrahydrodipicolinate-synthase	gnl|CDD|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	2.54619e-165
NC_021214.1|WP_004081881.1|1517309_1518020_-|diaminopimelate-epimerase	gnl|CDD|223331	COG0253, DapF, Diaminopimelate epimerase [Amino acid transport and metabolism].	1.58035e-70
NC_021214.1|WP_004081910.1|1527975_1528254_+|ferredoxin-family-protein	gnl|CDD|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	1.37238e-41

Protein sequences

>NC_021214.1|WP_004081884.1|1518024_1519002_-|aspartate-semialdehyde-dehydrogenase
MKVGVVGATGEVGRTMVKVLEEFNVPVTELRLFASERSVGKEIEFKGEKFKVELLTEESMKWKCDYFLFSAGASVSRKFAPIAAENGVTVIDNSSAFRMEKEIPLVVPEVNAYLLKGYTGIIANPNCSTIQMILSIYKLHEVYGIEEIFVSTYQSVSGAGHKGIEELLAQERGENVMKVFPKPIHRNVIPLIGDIQENLFSQEEMKMVNETRKILNDYSIRVYPTTVRVPVLYGHSEAIMVRLKKPYESLEKVREVIASGEDVVVTDDLITPVDVAGKNETYVCRLRATDERSILFWNVADNIRVGAATNAVRILLKHAEMNGKV
>NC_021214.1|WP_004081881.1|1517309_1518020_-|diaminopimelate-epimerase
MCYSANGNTFLIVDNTQKRIPEEKKPDFVRENVGDLDGVIFVELVDGKYFMDYYNRDGSMAAFCGNGARAFSQYLIDRGWIKEKEFTFLSRAGEIKVIVDDSIWVRMPGVSEKKEMKVDGYEGYFVVVGVPHFVMEVKGIDELDVEKLGRDLRYKTGANVDFYEVLPDRLKVRTYERGVERETKACGTGVTSVFVVYRDKTGAKEVKIQVPGGTLFLKEENGEIFLRGDVKRCSEE
>NC_021214.1|WP_004081879.1|1516440_1517325_-|4-hydroxy-tetrahydrodipicolinate-synthase
MFRGVGTAIVTPFKNGELDLESYERLVRYQLENGVNALIVLGTTGESPTVNEDEREKLVSRTLEIVDGKIPVIVGAGTNSTEKTLKLVKQAEKLGANGVLVVTPYYNKPTQEGLYQHYKYISERTDLGIVVYNVPGRTGVNVLPETAARIAADLKNVVGIKEANPDIDQIDRTVSLTKQARSDFMVWSGNDDRTFYLLCAGGDGVISVVSNVAPKQMVELCAEYFSGNLEKSREVHRKLRPLMKALFVETNPIPVKAALNLMGFIENELRLPLVPASEKTVELLRNVLKESGLL
>NC_021214.1|WP_004081877.1|1515793_1516444_-|4-hydroxy-tetrahydrodipicolinate-reductase
MKYGIVGYSGRMGQEIQKVFSEKGHELVLKVDVNGVEELDSPDVVIDFSSPEALPKTVDLCKKYRAGLVLGTTALKEEHLQMLRELSKEVPVVQAYNFSIGINVLKRFLSELVKVLEDWDVEIVETHHRFKKDAPSGTAILLESALGKSVPIHSLRVGGVPGDHVVVFGNIGETIEIKHRAISRTVFAIGALKAAEFLVGKDPGMYSFEEVIFGGE
>NC_021214.1|WP_004081875.1|1515090_1515792_-|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase
MDAREIIEMIAKAKKKTPIVAYIKGDLAGIDFSSFKFFGDERFGILFGEYEDFKKLLEEHREKIEDYHLEVKARNSALPLADLTKYKARIEPGAIIRDMVEIGEGAVIMMGAVINVGAVIGEGTMIDMNAVVGGRAIIGKKCHIGAGAVIAGVIEPPSAKPVVIEDEVLVGANAVILEGVTVGKGAVVAAGAVVTKDVPPYTVVAGVPARVIKQIDEKTKEKTKIVDELRNLE
>NC_021214.1|WP_004081873.1|1513869_1515075_-|aspartate-kinase
MNVVVQKYGGSSVATPERIKNVAQRIKKKVDEGYKVVVVVSAMGKTTDNLIKLAKEISPRPDSRELDMLLATGEQVSAALLSMALKDLGVKAKSLNAFQVKIKTTPHHTSARIVDIDDSVIRENLKDYDVLVVTGFQGVNEHGDLTTLGRGGSDTSAVALAAKLRVPCEIYSDVDGIYTCDPRVHPRAKKLAYITYDEALELTALGAKVLHSRSVEIAKKYGIPIYCASSFTEEEGTMVVERLPEWLEEPVVTGATISHGQIKVSISFLPKDVKYITAIFEEVGKRALNVDMISLVPSNGKVFLSFTILEDHKEDLDEALKEALRDVEGWKSTYEGGFAKLSIVGVGMRTSPGVAARFFEALERAGVTPELVTTSEIKISCLVPEEKAEEALKSVIEEFEL
>NC_021214.1|WP_004081870.1|1512699_1513860_-|diaminopimelate-decarboxylase
MDILRKVAEIHGTPTYVYFEETLRKRSRLVKEVFEGVNLLPTFAVKANNNPVLLKILREEGFGMDVVTKGELLAAKLAGVPSHTVVWNGNGKSRDQMEHFLREDVRIVNVDSFEEMEIWRELNPEGVEYFIRVNPEVDAKTHPHISTGLKKHKFGIPLEDLDSFMERFRSMNIRGLHVHIGSQITRVEPFVEAFSKVVRASERYGFEEINIGGGWGINYSGEELDLSSYREKVVPDLKRFKRVIVEIGRYIVAPSGYLLLRVVLVKRRHNKAFVVVDGGMNVLIRPALYSAYHRIFVLGKQGKEMRADVVGPLCESGDVIAYDRELPEVEPGDIIAVENAGAYGYTMSNNYNSTTRPAEVLVRENGRISLIRRRETEMDIFKDVVM
>NC_021214.1|WP_004081868.1|1511625_1512699_-|amidohydrolase
MDEIELRHILHMNPELSFKEYRTKETLRKAVIEIGYEKIIEVAGTGLVIEKKETEDPYVVLRADMDALPIKEETGWEFASRNEYMHACGHDFHMSALYGAMKRLRNVKKNFLFVFQPAEETGGGAKEVVDFLKDKYEIKAAVGFHVTDEYDAGTVASRPGVLFASATEFDVYFKGVPAHVAFAEKGKDALKAAVSFLGWLYNKKWNALVGVGKISGGRARNIVPDEIKLEGTIRSEALRITEEVISNMVKQLGELKEEMGVDFAVERGSVYPEVKVDQNLFETLRETCQRLGFSFVECDMKWTGEDFGYFSQVFPSLLFWFGVGEGERFGLHHPRFLPNDRYIPMAADLLAELAMVI
>NC_021214.1|WP_004081866.1|1511200_1511611_-|transcriptional-repressor
MTTEEIIERLKSKKVKLTTQRMEIIKFVSEMKEGHFEAKELFAILSKKVPSLSIATLYSVLYLLVDLGVIYAFSDGQKTIFDFNPEPHGHFICRECGKIEDVEIRELKLGEVKGKREKIELVIKGICEECLKKVKD
>NC_021214.1|WP_004081864.1|1510811_1511204_-|hypothetical-protein
MRYLVQLFSLLLVIIGILGLVVWAGLYFLAPYIEGFAGIKLPENIANVLLACFLPILGSGILLNFYTSSGIKWFVVLGFVVLSVSFVSEIYGLYILRGIFSKIAPAYLIFLLFTMVSLAYFLTIIRRDED
>NC_021214.1|WP_010865354.1|1520626_1521403_+|endoglucanase
MVVLMTKPGTSDFVWNGIPLSMELNLWNIKEYSGSVAMKFDGEKITFDADIQNLSPKEPERYVLGYPEFYYGYKPWENHTAEGSKLPVPVSSMKSFSVEVSFDIHHEPSLPLNFAMETWLTREKYQTEASIGDVEIMVWFYFNNLTPGGEKIEEFTIPFVLNGESVEGTWELWLAEWGWDYLAFRLKDPVKKGRVKFDVRHFLDAAGKALSSSARVKDFEDLYFTVWEIGTEFGSPETKSAQFGWKFENFSIDLEVRE
>NC_021214.1|WP_004081891.1|1521399_1522224_+|endoglucanase
MRWAVLLMVVFSALLFSSEVVLTSVGATDISFNGFPVTMELNFWNVKSYEGETWLKFDGEKVEFYADLYNIVLQNPDSWVHGYPEIYYGYKPWAGHNSGVEFLPVKVKDLPDFYVTLDYSIWYENNLPINLAMETWITRSPDQTSVSSGDAEIMVWFYNNVLMPGGQKVDEFTTTVEINGVKQETKWDVYFAPWGWDYLAFRLTTPMKEGKVKINVKDFVQKAAEVVKKHSTRIDNFEELYFCVWEIGTEFGDPNTTAAKFGWTFRDFSVEVVK
>NC_021214.1|WP_004081893.1|1522343_1522781_+|ferritin
MKVSDILTVAIRLEEEGERFYRELSEHFNGEIKKTFLELADQERIHAEIFRKMSDQENWDEVDSYLAGYAFYEVFPDTSEILRRKDLTLKEVLDIAISVEKDSIILYYELKDGLVNSDAQKTVKKIIDQEKEHLRKLLEMKREST
>NC_021214.1|WP_004081895.1|1522742_1523165_-|RrF2-family-transcriptional-regulator
MFGKCQKHVRYALRLLVRLSLENRPMSSSELAEKELITRNFALKVLHYLKRSGLVNSIKGKNGGFVLAKSPDEISFLDVISVFEKDLVIVDCNSRCKNYRACRVKYFWNWLSDYLKDLFSNITIKDIASGTFTFHLEKLS
>NC_021214.1|WP_004081897.1|1523192_1524062_+|1,4-dihydroxy-2-naphthoate-octaprenyltransferase
MKYFVAVRPFSFVASAFPVTVGAMLAEEFSLIRYILSLIASIFLHAGVNTTNDYFDYKKGVDTKDSLGSSGLLVSGKITPREELLLSVFCYAVSVVLGLVLIKISGPALLWLGLTGLVLGYAYTGHPFYLKYKSLGMFLVFILMGPLMVLGAYYVQTGRFSLEALLVSIPVGIATDLILLANEIRDSEFDRRSGIKTLPILIGDRAASFLYAVLTGLIYVFIVILVSTGVFRVISLVSLVSLPLYIRVIKQLFQKSAGRKNAREIADVDKMSALAEMILFVSMILGLLR
>NC_021214.1|WP_004081900.1|1524067_1524688_+|CPBP-family-intramembrane-metalloprotease
MVKRISEISFLSVLIGLFLGWYFVFQVNMLDFWWRMFMTTLIFSVISIFLGGKRNIKPNKYEAPLAIYSAVAAYLLFVVGYLISLLIPPFHRDVVSVYGLAEGQNALKVIILLVFIAFFEEIIWRGFVTEFLLQRLDVVPSILISSLLYSVVHVFTGNMALIVGAFVLGIILSLLYVITGKVSTPAFAHALWSLLIFVVLPLKGGF
>NC_021214.1|WP_004081902.1|1524789_1525647_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNVVVCIKQVPDTTNVRIDRKTNNLVREGVPSIINPDDERALELASQLKEKFGATVYVITMGPPQAKEALKDAIAFGLDEAVHLSDRTFAGADTLATTYTLYWGIKKIEERIGKIDLILTGKQAVDGDTGQVGPGLATRFGYALGAYVVRIEEIDPEKKEMVIVRRLDQGFEKIRLKLPAVLTITDELNKPRYADLPNLIRAIRYEPIVWTHKDLGLDPKKCGFFGSPTRVVSTNIPPARKGGDIISKNEDPEVAAEKLIEALKKFEAVRLVEALKPVLEGEKDE
>NC_021214.1|WP_004081904.1|1525639_1526656_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MSEKKIIFVLIEHHGGKAHPVSWELIGKARDLASKLENSEVWGVLLGEGLESVAKEAIQRGADKVLYVKNREFNTYVNYLYKKALVDMVRKYRPEIFLIGATLEGRELAGMVATELETGLTADCTGLDIIPDKKLLAMTRPTFGGNLMATIMCPDHRPQMATVRPGVMKELPPDPERTGEIIEEEYDLGTFDKLIEILETIPLQTQVNLEYAPVVVAGGKGVGGPEGFKKLKELADLLGGEVGASRAAVKAGWISPEHQVGQTGKTVRPVLYFACGISGAIQHVVGIKESEIIVAINIDEKAPIFDIADIGIVGDLHKVVPALTAKLRELLNKSGVKK
>NC_021214.1|WP_004081907.1|1526652_1527969_+|NAD(P)/FAD-dependent-oxidoreductase
MKIEFDVVVVGAGPSGLSCAYVLAKNGLKVAVVEKGEYPGSKNVMGGVLYVHPLKEIMPDFLEKAANSKALERNVIEQNLWLLGNEGVIKIGHRNVEWKENPNAFTVLRANFDRWFAQEVEKAGALIIPKTKVEDFLRNEKGEIAGVVTSRPKGEIHSKAVVIAEGVNPILTMKAGLRKEDLKPHMVAVAVKEVISVPEDVVNRVFGVEGNDGATIELLGSWSEGMFGMGFLYANRSSVSLGCGVLLEDLRKKKIKPYQLLENLKNHPVISDMLGEYRNNTMEYLAHLIPEGGYYAMPKVYGDRVLVCGDAAMLVNSIHREGSNHAITSGRLAAETLLEAFEKGDFSEKILKNYYLRLKESFILKDLEKYKDLMPTMEKNHQFVEIYPDLANDALKRFLQVDGTPKWDVQKQIADMVLSRRSLIGISLDLLRFWRAVR
>NC_021214.1|WP_004081910.1|1527975_1528254_+|ferredoxin-family-protein
MRIEDKLYLNRYRTDEENPHLKIKDESICAEKCSDRPCVSCCPADVYEWTESGMEVKFEGCLECGTCRIVCPFGNIEWNYPRGNYGVLYKFG

Crispr_ID: NC_021214_7

• CRISPR_ID: NC_021214_7
• CRISPR_location: 1631807-1632034
• CRISPR_type: Orphan
• Repeat_type: III-A
• Spacer_info: 3 spacers

Consensus repeat of NC_021214_7

Consensus_repeat	Method
TGTTTCCATACCTCTAAGGAAGTATTGAAAC	CRT
GTTTCAATACTTCCTTAGAGGTATGGAAAC	PILER-CR
GTTTCCATACCTCTAAGGAAGTATTGAAAC	CRISPRCasFinder

spacers of NC_021214_7

>7.1|1631838|35|NC_021214|CRT
ACAAGCGTTGTGCCATCACTACTTGTTCGAAGCCC
>7.2|1631904|34|NC_021214|CRT
AGACGTTCCTGTCGCTGGTAGTGTCGAATATTCG
>7.3|1631969|35|NC_021214|CRT
TTGTGTCTGAAGAATGAGCATCGAGTTCTACACGA
>7.4|1631838|36|NC_021214|PILER-CR,CRISPRCasFinder
ACAAGCGTTGTGCCATCACTACTTGTTCGAAGCCCA
>7.5|1631904|35|NC_021214|PILER-CR,CRISPRCasFinder
AGACGTTCCTGTCGCTGGTAGTGTCGAATATTCGT
>7.6|1631969|36|NC_021214|PILER-CR,CRISPRCasFinder
TTGTGTCTGAAGAATGAGCATCGAGTTCTACACGAT

CRISPR arrays and Neighbor proteins around NC_021214_7

CRISPR arrays

The CRISPR arrays of NC_021214_7

>merge|NC_021214|7|1631807-1632034|CRT,PILER-CR,CRISPRCasFinder
TGTTTCCATACCTCTAAGGAAGTATTGAAACACAAGCGTTGTGCCATCACTACTTGTTCGAAGCCCAGTTTCCATACCTCTAAGGAAGTATTGAAACAGACGTTCCTGTCGCTGGTAGTGTCGAATATTCGTGTTTCCATACCTCTAAGGAAGTATTGAAACTTGTGTCTGAAGAATGAGCATCGAGTTCTACACGATGTTTCCATACCTCTAAGGAAGTATTGAAAC

>NC_021214|7|6|1631807-1632034|CRT
TGTTTCCATACCTCTAAGGAAGTATTGAAAC	ACAAGCGTTGTGCCATCACTACTTGTTCGAAGCCC
AGTTTCCATACCTCTAAGGAAGTATTGAAAC	AGACGTTCCTGTCGCTGGTAGTGTCGAATATTCG
TGTTTCCATACCTCTAAGGAAGTATTGAAAC	TTGTGTCTGAAGAATGAGCATCGAGTTCTACACGA
TGTTTCCATACCTCTAAGGAAGTATTGAAAC

>NC_021214|7|6|1631808-1632034|PILER-CR
GTTTCCATACCTCTAAGGAAGTATTGAAAC	ACAAGCGTTGTGCCATCACTACTTGTTCGAAGCCCA
GTTTCCATACCTCTAAGGAAGTATTGAAAC	AGACGTTCCTGTCGCTGGTAGTGTCGAATATTCGT
GTTTCCATACCTCTAAGGAAGTATTGAAAC	TTGTGTCTGAAGAATGAGCATCGAGTTCTACACGAT
GTTTCCATACCTCTAAGGAAGTATTGAAAC

>NC_021214|7|7|1631808-1632034|CRISPRCasFinder
GTTTCCATACCTCTAAGGAAGTATTGAAAC	ACAAGCGTTGTGCCATCACTACTTGTTCGAAGCCCA
GTTTCCATACCTCTAAGGAAGTATTGAAAC	AGACGTTCCTGTCGCTGGTAGTGTCGAATATTCGT
GTTTCCATACCTCTAAGGAAGTATTGAAAC	TTGTGTCTGAAGAATGAGCATCGAGTTCTACACGAT
GTTTCCATACCTCTAAGGAAGTATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021214.1|WP_004082152.1|1636822_1637104_-|DUF503-domain-containing-protein	unknown	unknown	gnl|CDD|224467
NC_021214.1|WP_004082120.1|1626767_1627391_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_021214.1|WP_004082140.1|1633417_1634314_+|quinolinate-synthase-NadA	unknown	unknown	gnl|CDD|236489
NC_021214.1|WP_004082149.1|1636225_1636822_-|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)-YqeK	unknown	unknown	gnl|CDD|224627
NC_021214.1|WP_004082118.1|1626129_1626750_+|hypothetical-protein	unknown	unknown	gnl|CDD|224331
NC_021214.1|WP_004082145.1|1635130_1635589_-|YaaR-family-protein	unknown	unknown	gnl|CDD|224642
NC_021214.1|WP_004082147.1|1635585_1636242_-|hypothetical-protein	unknown	unknown	unknown
NC_021214.1|WP_004082116.1|1623578_1626137_+|SMC-family-ATPase	unknown	unknown	gnl|CDD|223496
NC_021214.1|WP_004082129.1|1629598_1630108_+|dihydrofolate-reductase	unknown	unknown	gnl|CDD|223340
NC_021214.1|WP_008194698.1|1634318_1635140_+|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl|CDD|272894
NC_021214.1|WP_004082138.1|1632679_1633405_+|aspartate-dehydrogenase	unknown	unknown	gnl|CDD|163567
NC_021214.1|WP_004082112.1|1622052_1622439_+|hypothetical-protein	unknown	unknown	unknown
NC_021214.1|WP_004082156.1|1638388_1640440_-|elongation-factor-G	unknown	unknown	gnl|CDD|237186
NC_021214.1|WP_004082125.1|1628204_1629611_+|NADPH-dependent-glutamate-synthase	unknown	unknown	gnl|CDD|183780
NC_021214.1|WP_004082131.1|1630143_1631727_+|bifunctional-aspartate-carbamoyltransferase-catalytic-subunit/aspartate-carbamoyltransferase-regulatory-subunit	unknown	unknown	gnl|CDD|237369
NC_021214.1|WP_004082158.1|1640439_1642101_-|phosphodiester-glycosidase-family-protein	unknown	unknown	gnl|CDD|378342
NC_021214.1|WP_004082110.1|1619692_1622056_+|endopeptidase-La	unknown	unknown	gnl|CDD|223542
NC_021214.1|WP_004082114.1|1622440_1623589_+|exonuclease-SbcCD-subunit-D	unknown	unknown	gnl|CDD|223497
NC_021214.1|WP_004082122.1|1627374_1628208_+|sulfide/dihydroorotate-dehydrogenase-like-FAD/NAD-binding-protein	unknown	unknown	gnl|CDD|235747
NC_021214.1|WP_004082154.1|1637118_1638387_-|alpha-amylase	unknown	unknown	gnl|CDD|200452

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021214.1|WP_004082120.1|1626767_1627391_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.72786e-71
NC_021214.1|WP_004082125.1|1628204_1629611_+|NADPH-dependent-glutamate-synthase	gnl|CDD|183780	PRK12831, PRK12831, putative oxidoreductase; Provisional.	0
NC_021214.1|WP_004082149.1|1636225_1636822_-|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)-YqeK	gnl|CDD|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	4.67197e-75
NC_021214.1|WP_004082118.1|1626129_1626750_+|hypothetical-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	0.00623292
NC_021214.1|WP_004082145.1|1635130_1635589_-|YaaR-family-protein	gnl|CDD|224642	COG1728, COG1728, Uncharacterized protein conserved in bacteria [Function unknown].	1.24321e-54
NC_021214.1|WP_004082116.1|1623578_1626137_+|SMC-family-ATPase	gnl|CDD|223496	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair].	1.58929e-85
NC_021214.1|WP_004082129.1|1629598_1630108_+|dihydrofolate-reductase	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	5.95461e-39
NC_021214.1|WP_008194698.1|1634318_1635140_+|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl|CDD|272894	TIGR00078, Probable_nicotinate-nucleotide_pyrophosphorylase, nicotinate-nucleotide pyrophosphorylase. Synonym: quinolinate phosphoribosyltransferase (decarboxylating) [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	1.84242e-122
NC_021214.1|WP_004082138.1|1632679_1633405_+|aspartate-dehydrogenase	gnl|CDD|163567	TIGR03855, NAD_NadX, aspartate dehydrogenase. Members of this protein family are L-aspartate dehydrogenase, as shown for the NADP-dependent enzyme TM_1643 of Thermotoga maritima. Members lack homology to NadB, the aspartate oxidase (EC 1.4.3.16) of most mesophilic bacteria (described by TIGR00551), which this enzyme replaces in the generation of oxaloacetate from aspartate for the NAD biosynthetic pathway. All members of the seed alignment are found adjacent to other genes of NAD biosynthesis, although other uses of L-aspartate dehydrogenase may occur.	7.75234e-113
NC_021214.1|WP_004082110.1|1619692_1622056_+|endopeptidase-La	gnl|CDD|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NC_021214.1|WP_004082156.1|1638388_1640440_-|elongation-factor-G	gnl|CDD|237186	PRK12740, PRK12740, elongation factor G-like protein EF-G2.	0
NC_021214.1|WP_004082140.1|1633417_1634314_+|quinolinate-synthase-NadA	gnl|CDD|236489	PRK09375, PRK09375, quinolinate synthase NadA.	8.06898e-160
NC_021214.1|WP_004082131.1|1630143_1631727_+|bifunctional-aspartate-carbamoyltransferase-catalytic-subunit/aspartate-carbamoyltransferase-regulatory-subunit	gnl|CDD|237369	PRK13376, pyrB, bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit; Provisional.	0
NC_021214.1|WP_004082158.1|1640439_1642101_-|phosphodiester-glycosidase-family-protein	gnl|CDD|378342	pfam09992, NAGPA, Phosphodiester glycosidase. This is a family conserved from bacteria to humans. The structure of a member from Bacteroides has been crystallized and modelled onto the luminal region of the human member of the family, the transmembrane glycoprotein N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. There is some conservation of potentially functional residues, implying that in the bacterial members this family acts in some way as a phosphodiester glycosidase. The human protein is also present, so the eukaryotic members are likely to be catalyzing the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides.	9.70521e-21
NC_021214.1|WP_004082152.1|1636822_1637104_-|DUF503-domain-containing-protein	gnl|CDD|224467	COG1550, COG1550, Uncharacterized protein conserved in bacteria [Function unknown].	8.45038e-39
NC_021214.1|WP_004082114.1|1622440_1623589_+|exonuclease-SbcCD-subunit-D	gnl|CDD|223497	COG0420, SbcD, DNA repair exonuclease [DNA replication, recombination, and repair].	7.41455e-66
NC_021214.1|WP_004082122.1|1627374_1628208_+|sulfide/dihydroorotate-dehydrogenase-like-FAD/NAD-binding-protein	gnl|CDD|235747	PRK06222, PRK06222, sulfide/dihydroorotate dehydrogenase-like FAD/NAD-binding protein.	2.04202e-171
NC_021214.1|WP_004082154.1|1637118_1638387_-|alpha-amylase	gnl|CDD|200452	cd11313, AmyAc_arch_bac_AmyA, Alpha amylase catalytic domain found in archaeal and bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase). AmyA (EC 3.2.1.1) catalyzes the hydrolysis of alpha-(1,4) glycosidic linkages of glycogen, starch, related polysaccharides, and some oligosaccharides. This group includes firmicutes, bacteroidetes, and proteobacteria. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	3.60264e-161

Protein sequences

>NC_021214.1|WP_004082131.1|1630143_1631727_+|bifunctional-aspartate-carbamoyltransferase-catalytic-subunit/aspartate-carbamoyltransferase-regulatory-subunit
MKRDFLGRTLAVIEDLSVEEQMFLYEKTRELKQRWYSGEDVSDFRIKKRNVGIYIVFVEPSTRTKESFINAAKFHSGPNVKVNVFDSEHSSFNKQESYTDTFSMLTGYSDYSIFVVRTRLEGVCRLLERRISEFASRNGIEVPSFINAGDGKHEHPTQELLDEYTFLEQNGFDNSFIHVALVGDLLHGRTVHSKVNGLKIFKNVKVDLVAPEELMMPEHYVEKMKKNGFEVRIFSSIREYLDQKDVAKIWYFTRLQLERMGEDILEKVHVLREAVTFKKEYLDALPEGVKFYHPLPRHKVYPTIPNFLDTLPLNGWETQARNGYWVRIVLLSMFGGALEAPFDTSKKEEKPEEDFIIPAPITHGSKGVQKEGKRGIKPIENGTVIDHIAKGKTPEEIYSTILKIRKILRLYDVDSADGIFRSSDGSFKGYISLPDRYLSKKEIKKLSAISPNTTVNIIKNSTVVEKYRIKLPPTIYGFEELRCKNENCITNPAHGENASPSFVRNEKGQFICEYCETPHSFEEIWSI
>NC_021214.1|WP_004082129.1|1629598_1630108_+|dihydrofolate-reductase
MAKVIFVLAMDVSGKIASSVESWSSFEDRKNFRKITTEIGNVVMGRITFEEIGRPLPERLNVVLTRRPKTSNNPSLVFFNGSPADVVKFLEGKGYERVAVIGGKTVFTEFLREKLVDELFVTVEPYVFGKGIPFFDEFEGYFPLKLLEMRRLNERGTLFLKYSVEKSHR
>NC_021214.1|WP_004082125.1|1628204_1629611_+|NADPH-dependent-glutamate-synthase
MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK
>NC_021214.1|WP_004082122.1|1627374_1628208_+|sulfide/dihydroorotate-dehydrogenase-like-FAD/NAD-binding-protein
MNEIVKKVKIAEDVFDFWIHSPSVSKEARPGQFVVIRLHEKGERIPLTVADTKPEEGLFRMVVKVVGKTTHELSLKKEGDTILDVVGPLGNPSEIENYGNVLLVGGGVGIATLYPIAKALKEAGNNITTVLGARTKDYLIMVDEFKEISDVLLVTDDGSAGMKGVVTDAMDKLFRERKFDICWAVGPTIMMKFCTLKAREFGVPIWVSLNPIMVDGTGMCGACRVTVSGQIKFACVDGPEFRGEEVDWDELLKRLAQYREQEKISYERFLKTAGESE
>NC_021214.1|WP_004082120.1|1626767_1627391_+|ABC-transporter-ATP-binding-protein
MKKSYGKKKKVLDGVSFSLEKGKSLGIVGQNSAGKTTLLKILATILKPDEGRLFLFEKNALKDLSYIRKRIAFVPEFPALLEELTVRENLLFFSRLRGVKMENFIVSELMLEPFMGTLVRNASKGVKQRTALAVALFGNPELLILDEPTSGLDVESASIVRSKLKRLKEEGITVIISSHIREDIEELCDEILVINGENGGDGFERDR
>NC_021214.1|WP_004082118.1|1626129_1626750_+|hypothetical-protein
MSDEKRKKEELIERIVSEKGEEAFPKLLELLEDEDPEVKEIVSEVFYRLGDRAREFLFNEIQKRRERGFEKNDITNLYIIDILGDLGEKRMKNVLYELMEKYDSEEALLIIYEALAKIGEGEVFLPELEYLMFEDAYRKELCEQVAMVLANIPTERSLRILLKALKSKEFSEDQKEFFRRAVEMILYRKPELSKYVTDEERKELGL
>NC_021214.1|WP_004082116.1|1623578_1626137_+|SMC-family-ATPase
MRPERLTVRNFLGLKNVDIEFQSGITVVEGPNGAGKSSLFEAISFALFGNGIRYPNSYDYVNRNAVDGTARLVFQFERGGKRYEIIREINALQRKHNAKLSEILENGKKAAIAAKPTSVKQEVEKILGIEHRTFIRTVFLPQGEIDKLLISPPSEITEIISDVFQSKETLEKLEKLLKEKMKKLENEISSLQALYTAIWKYLEENDLEVLKSELKTVSEKKKELLKKREELQKEEEQLKRLLEKYRELVKKKERLRVLSLRRNELQKEVIYEQKVKKAKELEPLFREIYLRQREFERFSQELNSREKRYKELESEKEAISKEIPVHRERLSKLEEIGEKIKEELDLLEKVLKASRPLLEQRIRLKENLTRLEEEFRRLVGEKEKREKELLSIEKTENETKNELEKLLDELSILKKDHMKWLAYQIASSLNEGDTCPVCGGVFHGKVEAVEFNIDEFEKLDQKRSELENTLNVLKERKKSLSSLIEDLLMKIEEGKKNLKSIRNQIEKIEEELHRLGYSEDLEEKLDEKRKKLRKIEEERHSISQKITAADVQISQIENQLKEIKGEIEAKRETLKEQREEMDQLKSDFFDRLRKIGIGFEEFRILVKEEVKDAEKELGVVETEIRLLEESLKELESENVRDVSEDYEKVRNQLEALSQEISDLERKEGRLNHLIEETLRRERELKSLEKKLKEMSDEYNNLDLLRKYLFDKSNFSRYFTGRVLEAVLKRTKAYLDILTNGRFDIDFDDEKGGFIIKDWGIERPARGLSGGERALISISLAMSLAEVASGRLDAFFIDEGFSSLDTENKEKIASVLKELERLNKVIVFITHDREFSEAFDRKLRITGGVVVNE
>NC_021214.1|WP_004082114.1|1622440_1623589_+|exonuclease-SbcCD-subunit-D
MKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIERKSRREIEEVLRESPEEFKEELDKLDYFELFKEYLKKREENHEKLLKILDELLDEVKKSEA
>NC_021214.1|WP_004082112.1|1622052_1622439_+|hypothetical-protein
MKRDIFYVIILTVFAVLFMLTYFSYRNLAVKLTRMEKTLKAYELYIFSDYENFENYVKKEGLKIEGMELLKEKKARSLIAEGKDLFETANYGEALVFFEKALNLSDNEEIKKIASFYLEECRKKLAGD
>NC_021214.1|WP_004082110.1|1619692_1622056_+|endopeptidase-La
MSKKSKDTEKSFKILEKYASQQEKELEIPDSLPCIPLRNGMGVFPNTVVPFYVGRTGSLIALEEAMEKYNRLLLVVNQKDPSVEIPEPEDLYKVGTVVKVLQIMKLPDDTFKVLVEGLERAQIEEFVSTDPFFLTKIKILKVKYRKTKKLEALMRSVKDKAVRYFNLTHRFPQETLVTLKEMQDPDKLADFVASILPVPLETKQELLETVHPLERLEKILSILVKEIEILEIEEEIEKKVKDRIEKTQREYVLREKLRAIKEELGVEEELEIKELYEKVEKGDYPDYVKEKAYKEIQRLEKMSPYSAEATVVRTYLDWLLNLPWNVATEDRLDIKEARKILDKNHYGLGEVKERILEYLVARKFSKNLKAPILCLVGPPGVGKTSLGRTIAEAMGRKFGRMSLGGLRDEAEIKGHRRTYVGALPGRIIQIIRRLGTKNPVILLDEVDKMGISFQGDPASALLEVLDPEQNKDFVDHYLEVPFDLSQVLFITTANVLHTIPPALRDRMEIIEIPGYSDPEKYHIARDYIIPKIARSYGLSKVMFTPGAIKKIIREYTKEAGVRNLERVIEKVIRKSLVKGEKKSFKITTKDVEELLGPPVFREEEILEEDTVGAVTGLAWTPVGGSVLIVESLLLPGRGNLILTGNMGDVMKESARIALSVVRKMCGEECREVFEKNDIHIHVPEGAVPKDGPSAGITITVALYSAVTGKKVRRDVAMTGEITLRGKILPVGGIKEKLLAAKRAGIKKVILPSRNRPDVEKIPKEYLNGMEIVYCSEIQEVLKEAIVR
>NC_021214.1|WP_004082138.1|1632679_1633405_+|aspartate-dehydrogenase
MTVLIIGMGNIGKKLVELGNFEKIYAYDRISKDIPGVVRLDEFQVPSDVSTVVECASPEAVKEYSLQILKNPVNYIIISTSAFADEVFRERFFSELKNSPARVFFPSGAIGGLDVLSSIKDFVKNVRIETIKPPKSLGLDLKGKTVVFEGSVEEASKLFPRNINVASTIGLIVGFEKVKVTIVADPAMDHNIHIVRISSAIGNYEFKIENIPSPENPKTSMLTVYSILRTLRNLESKIIFG
>NC_021214.1|WP_004082140.1|1633417_1634314_+|quinolinate-synthase-NadA
MVDEILKLKKEKGYIILAHNYQIPELQDIADFVGDSLQLARKAMELSEKKILFLGVDFMAELVKILNPDKKVIVPDRSATCPMANRLTPEIIREYREKFPDAPVVLYVNSTSECKTLADVICTSANAVEVVKKLDSSVVIFGPDRNLGEYVAEKTGKKVITIPENGHCPVHQFNAESIDAVRKKYPDAKVIVHPECPKPVRDKADYVGSTGQMEKIPEKDPSRIFVIGTEIGMIHKLKKKFPDREFVPLEMAVCVNMKKNTLENTLHALQTESFEVILPKEVIEKAKKPILRMFELMG
>NC_021214.1|WP_008194698.1|1634318_1635140_+|carboxylating-nicotinate-nucleotide-diphosphorylase
MEKILDLLMSFVKEDEGKLDLASFPLRNTTAGAHLLLKTENVVASGIEVSRMFLEKMGLLSKFNVEDGEYLEGTGVIGEIEGNTYKLLVAERTLLNVLSVMFSVATTTRRFAEKLKHAKIAATRKILPGLGVLQKIAVVHGGGDPHRLDLSGCVMIKDNHLKMYGSAERAVQEVRKIIPFTTKIEVEVENLEDALRAVEAGADIVMLDNLSPEEVKDISRRIKDINPNVIVEVSGGITEENVSLYDFETVDVISSSRLTLQEVFVDLSLEIQR
>NC_021214.1|WP_004082145.1|1635130_1635589_-|YaaR-family-protein
MRIDPLGGESLKNQEVKGKKSGKTSRVGESKKKEFFDILEDVKEDHFEKLLEEAVEEVIDSGNELVRSPTPSNLKRYKNAIKEFLKLIEKKIYKLAGSFDMNSGRARLHLVVEEVNEKLMDLTEKIMKNEWQTINLAARIEEINGLILNLYR
>NC_021214.1|WP_004082147.1|1635585_1636242_-|hypothetical-protein
MKRSSKIVLVIVLIAVALSAVLFLYYRSFLTSPDYKAAEVHYLFRVGDNSYFVRIDDSKRMVFVVSFPKESFDPERRETIISERPLSDLEKMENLLDVKAERAFYSVMSEEEFLKLCQDLLGKQCESFSNFVKEFSKRKLKFFDFLFVGSWLKKFGFNNLNRFSLYKFFEKISNYAVDVFEAPTVTEKPIVIEVQGKKYERLYLDSEKLKAISEEMKR
>NC_021214.1|WP_004082149.1|1636225_1636822_-|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)-YqeK
MVVITNELESIMERLLSRKRINHVRSVVEFSRKLGEMYGADSNKLELAAISHDLFRDVPPRKLLKMAQAYGLKISELERTHPVLLHGKVAAEFLKRRFNVEDEEVLNAVAYHTSGHVSFKTVGKILFIADSLEFTRDFPGVDELRRIAFRNLEEGFFQVLKNKIFYAVGKNYLLIPETVELWNSILMGRGGLVDEEVE
>NC_021214.1|WP_004082152.1|1636822_1637104_-|DUF503-domain-containing-protein
MSVGVVSLRVRLFGVRSLKEKRGILKRLMNDLRKKYNISISEVGAHDSKSFFEIGIAMVNTDRAVIERVFDSIIDYLDLYPGMEVEEIEREVW
>NC_021214.1|WP_004082154.1|1637118_1638387_-|alpha-amylase
MNFKRLIIYEAFARAYPGEKGKKFDSLIKDLERLKGMGINTVWLMPIHPTGIEGRKGTLGSPYAIRDYYEIDPLIGTKDDFKRFVKRAHELNMYVLMDMVLNHAAADNVLVREHPEWFLRDEKGNPTRKVPDWTDIVDFDYSNGELRKYMINMMKYWVEEFDVDGFRCDVAGLVPLDFWLQARKELDPVKRLIWLSETHDPYMYQAFDITYDYDGYYKFRDFIEGRGSLREYVDFLRMQDHMYPRGYIKMRFLENHDQPRIAKFIEEDSLVHWIAFLFTFKGVPLVHNGQEYGLKEDVDIFNEYTLPFPMEENRISILHRKLAHYRYGTSVFSEGEMLFVKNDQPEKVISYLWRYENRYILCMLNPLLENTKVTLDFSGIWESACIHSKNVFNDEIVRVPVKNSRATVEIGKEPLILSFVLY
>NC_021214.1|WP_004082156.1|1638388_1640440_-|elongation-factor-G
MGGLQNVRSAALIGHNGSGKSLLLAQILYKSGLIDKADTKYVDYDPVEEEKGASFSSHVASLEWKGKKVYLIDTPGFSDFISEVINGIFVSENIISVVNAVAGVEIQTERTWNMADEMKKPIIVFVNQMDKERANFENVVAELKERFSRKIVPVVVPIGAAENFEGVVDLLKKKAYRYDGDKVQEEDMPESFNDMRSEILEDIVEQDEELMMRYLDGEDIGYDELMRVLKEGYKKGEIVPVLSGSALKGIGLDLLLDYLGDIGVSPEEAPSYKALLEDGTEIEVKFSEEEPFCAYIFKSVVDQFVGRITFAKVIAGVLRPGDTVVNVQKDVTEKVGHVYVPILKQQKEVESAGPGEIVVLLKLKEGAVGETLAHRDRRVKIVPPAFPEPMFSRSVHPKSKSDIDKISSGLSRLSDSDPTFVWEYDPETGETVVSGLGAMHLDVMIERLKKIFGVDVEVGKPKIAYRETITTTAVAEHKHKKQTGGHGQYGHVKIQLEPLPRGQGYEFVDKIVGGVIPRNFIPSVDKGIREAMKKGVLAGYPVTDVRVILFDGSYHEVDSSDISFQIAAIQAFKKGMEAAKPVILEPIMEVEVFVPEENAGDVMGEISSRRGRPLGMEPSGKGMVKVKAEVPLAEMLDFSSKLSSITSGRGYFTMRFQRYEIVPPNIQEKIIEERRREMQEQEK
>NC_021214.1|WP_004082158.1|1640439_1642101_-|phosphodiester-glycosidase-family-protein
MKQIILVLLIFASVVFGSYLISGGKAFPLRTVFSEGIYYVCAEDLAPAGVGYIHSNGYHYIVYDNHVLFIKEHETIFDFVEKLSPPLFVDGLLFVPIDALKKVMEGYQMYTKGEKVLIYDSLPIVLSAAKEKNGVTITYTGTIVPDMVSVEKSMGRVRINLSPVVVSLPNVSEDIKVELEKNGLSFIVDVGNFYPDVEYSIGDGKLLFRFLLVEGFFGRLEVADGVVFERKIEEFDEGEKTVVNYLIMDPEKVTIKPVVSENGFGTIERLDEMVKRVGGIAGINGNYFDPVTKFPIGLVVIDGKPYSAMFSGRPVFAITEDNEVFIGRVIVDVTLMVKDVLFLVKGINTLGEGEVLVYTKEFSKEIPKKDDKIYFVVKDSKVSQIGYKSHAEDSEYVVSISKKYEEYLSDLKEGDEVYISLQPNIPLRIKQAVEGGPLLIQNGAPIPDAWEEKARYGGGIAYAKAPRTVIATKDGKLWFLVFEGYNHITRGLTYDELVDFLVSRGFEDAMCVDGGSSSVMAVAGSLFGRTENSTAAIPVGIVVWEKKKTEVGK

Crispr_ID: NC_021214_8

• CRISPR_ID: NC_021214_8
• CRISPR_location: 1779827-1780718
• CRISPR_type: TypeIII
• Repeat_type: III-A
• Spacer_info: 13 spacers
• Cas_protein_info: cas8b1,cas7,cas5,cas3,cas4,cas1,cas2,cmr1gr7,cas10,cmr3gr5,csx22,csm5gr7,csm4gr5,csm3gr7,csm2gr11,csx1

Consensus repeat of NC_021214_8

Consensus_repeat	Method
GTTTCCATACCTCTAAGGAATTATTGAAAC	CRISPRCasFinder
GTTTCCATACCTCTAAGGAATTATTGAAAC	CRT
GTTTCAATAATTCCTTAGAGGTATGGAAAC	PILER-CR

spacers of NC_021214_8

>8.1|1779857|35|NC_021214|CRISPRCasFinder
AGTATCGAAGATGAAGAAATCATACGGTTTGTGGG
>8.2|1779922|35|NC_021214|CRISPRCasFinder,CRT
TCTTCTTGATAGCCTTGTAGTTGTCTGTGGTCATG
>8.3|1779987|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
TTGTTTTTGGCATGCTGGCGCTGGCGCTGGCGGGCGC
>8.4|1780054|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
CAAGCCGAATTGGAAATGGAACGATGAAACAGAAGCT
>8.5|1780121|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
GTTCTCTCAATGTCACGTCTCATCACCTCTTCTTCG
>8.6|1780187|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
AGAAAGTAGTCGACAAGTTCGTTGATTGTCTCGTCGC
>8.7|1780254|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
AGAGCTCTCCCGGGCCGTACCATCCAGGCCACCCCA
>8.8|1780320|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
TACAGAACATTGCACTGGAAGAGAAGAAGCAGGAGA
>8.9|1780386|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
AGACATCTCGATCCTGATGAAGTAGGAGGGATACTTA
>8.10|1780453|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
AAATCAGGATTGAACCTGACGTAGAAGCTTTGTACAA
>8.11|1780520|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR
ACTTAAAGGAGGCAAAAAGACAGGAAAGAAGGGACGG
>8.12|1780587|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
AGGCAGATCTGAGGATCATTGCAGAGCGAGGAAACA
>8.13|1780653|36|NC_021214|CRISPRCasFinder,CRT,PILER-CR
AAGGAACTCAGGACGATTCTCTGGATCGGTCTCAAG

CRISPR arrays and Neighbor proteins around NC_021214_8

CRISPR arrays

The CRISPR arrays of NC_021214_8

>merge|NC_021214|8|1779827-1780718|CRISPRCasFinder,CRT,PILER-CR
GTCATTGCACCTGAAAGGAAGTATTGAAACAGTATCGAAGATGAAGAAATCATACGGTTTGTGGGCTTTTCATACCTCTAAGGAAGGATTGAATCTCTTCTTGATAGCCTTGTAGTTGTCTGTGGTCATGGTTTCCATACCTCTAAGGAAGTATTGAAACTTGTTTTTGGCATGCTGGCGCTGGCGCTGGCGGGCGCGTTTCCATACCTCTAAGGAAGTATTGAAACCAAGCCGAATTGGAAATGGAACGATGAAACAGAAGCTGTTTCCATACCTCTAAGGAATTATTGAAACGTTCTCTCAATGTCACGTCTCATCACCTCTTCTTCGGTTTCCATACCTCTAAGGAATTATTGAAACAGAAAGTAGTCGACAAGTTCGTTGATTGTCTCGTCGCGTTTCCATACCTCTAAGGAATTATTGAAACAGAGCTCTCCCGGGCCGTACCATCCAGGCCACCCCAGTTTCCATACCTCTAAGGAATTATTGAAACTACAGAACATTGCACTGGAAGAGAAGAAGCAGGAGAGTTTCCATACCTCTAAGGAATTATTGAAACAGACATCTCGATCCTGATGAAGTAGGAGGGATACTTAGTTTCCATACCTCTAAGGAATTATTGAAACAAATCAGGATTGAACCTGACGTAGAAGCTTTGTACAAGTTTCCATACCTCTAAGGAATTATTGAAACACTTAAAGGAGGCAAAAAGACAGGAAAGAAGGGACGGGTTTCCATACCTCTAAGGAATTATTGAAACAGGCAGATCTGAGGATCATTGCAGAGCGAGGAAACAGTTTCCATACCTCTAAGGAATTATTGAAACAAGGAACTCAGGACGATTCTCTGGATCGGTCTCAAGGTTTCCATACCTCTAAGGAATTATTGAAAC

>NC_021214|8|8|1779827-1780718|CRISPRCasFinder
GTCATTGCACCTGAAAGGAAGTATTGAAAC	AGTATCGAAGATGAAGAAATCATACGGTTTGTGGG
CTTTTCATACCTCTAAGGAAGGATTGAATC	TCTTCTTGATAGCCTTGTAGTTGTCTGTGGTCATG
GTTTCCATACCTCTAAGGAAGTATTGAAAC	TTGTTTTTGGCATGCTGGCGCTGGCGCTGGCGGGCGC
GTTTCCATACCTCTAAGGAAGTATTGAAAC	CAAGCCGAATTGGAAATGGAACGATGAAACAGAAGCT
GTTTCCATACCTCTAAGGAATTATTGAAAC	GTTCTCTCAATGTCACGTCTCATCACCTCTTCTTCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGAAAGTAGTCGACAAGTTCGTTGATTGTCTCGTCGC
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGAGCTCTCCCGGGCCGTACCATCCAGGCCACCCCA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TACAGAACATTGCACTGGAAGAGAAGAAGCAGGAGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGACATCTCGATCCTGATGAAGTAGGAGGGATACTTA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAATCAGGATTGAACCTGACGTAGAAGCTTTGTACAA
GTTTCCATACCTCTAAGGAATTATTGAAAC	ACTTAAAGGAGGCAAAAAGACAGGAAAGAAGGGACGG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGGCAGATCTGAGGATCATTGCAGAGCGAGGAAACA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAGGAACTCAGGACGATTCTCTGGATCGGTCTCAAG
GTTTCCATACCTCTAAGGAATTATTGAAAC

>NC_021214|8|7|1779892-1780718|CRT
CTTTTCATACCTCTAAGGAAGGATTGAATC	TCTTCTTGATAGCCTTGTAGTTGTCTGTGGTCATG
GTTTCCATACCTCTAAGGAAGTATTGAAAC	TTGTTTTTGGCATGCTGGCGCTGGCGCTGGCGGGCGC
GTTTCCATACCTCTAAGGAAGTATTGAAAC	CAAGCCGAATTGGAAATGGAACGATGAAACAGAAGCT
GTTTCCATACCTCTAAGGAATTATTGAAAC	GTTCTCTCAATGTCACGTCTCATCACCTCTTCTTCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGAAAGTAGTCGACAAGTTCGTTGATTGTCTCGTCGC
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGAGCTCTCCCGGGCCGTACCATCCAGGCCACCCCA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TACAGAACATTGCACTGGAAGAGAAGAAGCAGGAGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGACATCTCGATCCTGATGAAGTAGGAGGGATACTTA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAATCAGGATTGAACCTGACGTAGAAGCTTTGTACAA
GTTTCCATACCTCTAAGGAATTATTGAAAC	ACTTAAAGGAGGCAAAAAGACAGGAAAGAAGGGACGG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGGCAGATCTGAGGATCATTGCAGAGCGAGGAAACA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAGGAACTCAGGACGATTCTCTGGATCGGTCTCAAG
GTTTCCATACCTCTAAGGAATTATTGAAAC

>NC_021214|8|7|1779957-1780718|PILER-CR
GTTTCCATACCTCTAAGGAAGTATTGAAAC	TTGTTTTTGGCATGCTGGCGCTGGCGCTGGCGGGCGC
GTTTCCATACCTCTAAGGAAGTATTGAAAC	CAAGCCGAATTGGAAATGGAACGATGAAACAGAAGCT
GTTTCCATACCTCTAAGGAATTATTGAAAC	GTTCTCTCAATGTCACGTCTCATCACCTCTTCTTCG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGAAAGTAGTCGACAAGTTCGTTGATTGTCTCGTCGC
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGAGCTCTCCCGGGCCGTACCATCCAGGCCACCCCA
GTTTCCATACCTCTAAGGAATTATTGAAAC	TACAGAACATTGCACTGGAAGAGAAGAAGCAGGAGA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGACATCTCGATCCTGATGAAGTAGGAGGGATACTTA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAATCAGGATTGAACCTGACGTAGAAGCTTTGTACAA
GTTTCCATACCTCTAAGGAATTATTGAAAC	ACTTAAAGGAGGCAAAAAGACAGGAAAGAAGGGACGG
GTTTCCATACCTCTAAGGAATTATTGAAAC	AGGCAGATCTGAGGATCATTGCAGAGCGAGGAAACA
GTTTCCATACCTCTAAGGAATTATTGAAAC	AAGGAACTCAGGACGATTCTCTGGATCGGTCTCAAG
GTTTCCATACCTCTAAGGAATTATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021214.1|WP_004082353.1|1782960_1783536_-|hypothetical-protein	csx22	mkCas0064_csx22_CAS-III-A	unknown
NC_021214.1|WP_004082357.1|1786276_1786699_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	COG1421_csm2gr11_CAS-III-A	gnl|CDD|224339
NC_021214.1|WP_004082344.1|1772976_1773936_-|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl|CDD|187853
NC_021214.1|WP_004082348.1|1777242_1778142_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl|CDD|187821
NC_021214.1|WP_004082340.1|1768001_1768994_-|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	COG1769_cmr3gr5_CAS-III-B	gnl|CDD|224683
NC_021214.1|WP_174269897.1|1784644_1785502_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl|CDD|273866
NC_021214.1|WP_004082358.1|1786713_1788867_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	gnl|CDD|274209
NC_021214.1|WP_004082345.1|1773945_1774425_-|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl|CDD|366863
NC_021214.1|WP_008194418.1|1781693_1782164_+|hypothetical-protein	unknown	unknown	unknown
NC_021214.1|WP_004082350.1|1781352_1781703_+|J-domain-containing-protein	unknown	unknown	gnl|CDD|197617
NC_021214.1|WP_004082352.1|1782163_1782979_+|hypothetical-protein	unknown	unknown	unknown
NC_021214.1|WP_004082341.1|1768990_1771393_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cls000742_cas10_CAS-III	gnl|CDD|224272
NC_021214.1|WP_004082347.1|1776577_1777240_-|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl|CDD|131641
NC_021214.1|WP_004082349.1|1778116_1779757_-|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09672_cas8b1_CAS-I-B	gnl|CDD|274199
NC_021214.1|WP_004082354.1|1783508_1784648_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	gnl|CDD|224251
NC_021214.1|WP_004082343.1|1772707_1772971_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_021214.1|WP_015646196.1|1774421_1776587_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|224124
NC_021214.1|WP_004082356.1|1785519_1786263_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NC_021214.1|WP_004082359.1|1788887_1790534_-|CRISPR-associated-DxTHG-motif-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|187802
NC_021214.1|WP_004082342.1|1771395_1772724_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl|CDD|224286

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_021214.1|WP_004082353.1|1782960_1783536_-|hypothetical-protein	csx22	mkCas0064_csx22_CAS-III-A	1.5e-133	436.9	0.3
NC_021214.1|WP_004082357.1|1786276_1786699_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	COG1421_csm2gr11_CAS-III-A	5.7e-43	141.4	2.5
NC_021214.1|WP_004082344.1|1772976_1773936_-|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	1.8e-134	442.6	9.6
NC_021214.1|WP_004082348.1|1777242_1778142_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	1.6e-137	452.3	0.8
NC_021214.1|WP_004082340.1|1768001_1768994_-|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	COG1769_cmr3gr5_CAS-III-B	6.1e-150	493.5	0.6
NC_021214.1|WP_174269897.1|1784644_1785502_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	1.2e-91	301.9	1.3
NC_021214.1|WP_004082358.1|1786713_1788867_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	3.7e-180	595.6	37.5
NC_021214.1|WP_004082345.1|1773945_1774425_-|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	1.9e-44	146.4	0.0
NC_021214.1|WP_004082341.1|1768990_1771393_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cls000742_cas10_CAS-III	6.2e-229	756.8	11.0
NC_021214.1|WP_004082347.1|1776577_1777240_-|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	3.1e-91	299.9	0.0
NC_021214.1|WP_004082349.1|1778116_1779757_-|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09672_cas8b1_CAS-I-B	3.9e-201	664.2	12.7
NC_021214.1|WP_004082354.1|1783508_1784648_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	4e-127	419.6	3.6
NC_021214.1|WP_004082343.1|1772707_1772971_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	2e-31	103.0	0.5
NC_021214.1|WP_015646196.1|1774421_1776587_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	1.7e-131	434.5	9.8
NC_021214.1|WP_004082356.1|1785519_1786263_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	7.1e-92	301.7	0.2
NC_021214.1|WP_004082359.1|1788887_1790534_-|CRISPR-associated-DxTHG-motif-protein	csx1	cd09671_csx1_CAS-III	3.5e-91	300.8	8.7
NC_021214.1|WP_004082342.1|1771395_1772724_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	3.9e-183	603.6	3.7

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021214.1|WP_004082357.1|1786276_1786699_-|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|224339	COG1421, COG1421, CRISPR system related protein [Defense mechanisms].	9.67868e-34
NC_021214.1|WP_004082344.1|1772976_1773936_-|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.74885e-169
NC_021214.1|WP_004082348.1|1777242_1778142_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl|CDD|187821	cd09690, Cas7_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csh2 family.	1.36059e-151
NC_021214.1|WP_004082340.1|1768001_1768994_-|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl|CDD|224683	COG1769, COG1769, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	6.73273e-156
NC_021214.1|WP_174269897.1|1784644_1785502_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	8.42766e-103
NC_021214.1|WP_004082358.1|1786713_1788867_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl|CDD|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	0
NC_021214.1|WP_004082345.1|1773945_1774425_-|CRISPR-associated-protein-Cas4	gnl|CDD|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.42478e-61
NC_021214.1|WP_004082350.1|1781352_1781703_+|J-domain-containing-protein	gnl|CDD|197617	smart00271, DnaJ, DnaJ molecular chaperone homology domain.	5.62059e-24
NC_021214.1|WP_004082341.1|1768990_1771393_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|224272	COG1353, COG1353, Predicted CRISPR-associated polymerase [Defense mechanisms].	3.2408e-169
NC_021214.1|WP_004082347.1|1776577_1777240_-|type-I-B-CRISPR-associated-protein-Cas5	gnl|CDD|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.0811e-98
NC_021214.1|WP_004082349.1|1778116_1779757_-|TIGR02556-family-CRISPR-associated-protein	gnl|CDD|274199	TIGR02556, hypothetical_protein_MM_0564, CRISPR-associated protein, TM1802 family. This minor cas protein is found in CRISPR/cas regions of at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	0
NC_021214.1|WP_004082354.1|1783508_1784648_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl|CDD|224251	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	9.62566e-127
NC_021214.1|WP_004082343.1|1772707_1772971_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.2669e-30
NC_021214.1|WP_015646196.1|1774421_1776587_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.33636e-128
NC_021214.1|WP_004082356.1|1785519_1786263_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.59316e-112
NC_021214.1|WP_004082359.1|1788887_1790534_-|CRISPR-associated-DxTHG-motif-protein	gnl|CDD|187802	cd09671, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as DxTHG family.	1.98842e-73
NC_021214.1|WP_004082342.1|1771395_1772724_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl|CDD|224286	COG1367, COG1367, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	7.67651e-172

Protein sequences

>NC_021214.1|WP_004082349.1|1778116_1779757_-|TIGR02556-family-CRISPR-associated-protein
MLEKIYNLGKIGGDSFSNFAEEVPSDEGIAIFLESNSEGLVFKDVVSIEKKPGGKNSKIFLYRKQRGNFSSSVSPTMKFLDKSSGSRDPLERTFDVFLGFFDHPKISHIKDVLERNKEEIIDKLRNYDVKNRFLTISIDGKFPAEVPEILQAFEDKVTQKKTKGEAKCFLCGKEANSRLSDVFKFATFDKPGFTPFLSKKHPIQICDDCRSVLEKARRAIDEKLSFSFFSNNRILWIIPSVPDQDILESVIEKIYEIKDTDKNSKFRSFARLEEEIEKVLSENERAVYDFVLIEKEQQAERIVLHVEEVSPTRVRRILEESKKIESQLKEDGFKVSVNFSVIHKFFEDLDRYFNSLFSAVFSEGTFDKKLLLTLFLSKIRSDFFGNDTLLSAREAFATYVYLRRLNVLKGGASVLKGEDFFSRYPEFFDEPWKKAVFLEGVLANYLLYLQYVKRNSKAFTKKLKGLRLTKRDVEGLLPEIRAKIEAYGGMSESVAELFRETAEAFLEAGNWSASPDEISFVFVSGLSLGKTFFREVGVDESSEEQE
>NC_021214.1|WP_004082348.1|1777242_1778142_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MNPVKNRSEVLFIYDVKWANPNGDPLDENRPRFDEETSRLFVTDVRLKRTVRDYLAECYDETLWVTGEAVVPEDRVKELGIKDVNDACQKCIDIRLFGAVIPQSKKGAMESSITGPVQFRYGTSLHRVKLMTIQGTAAFATENSKQRSFREDQVVPYALIAFYGVINQNSAKFTGLTEEDVSKLLEGIWMGTKNLITRSKMEHNPRLLMRVVYKEGVNYHSGELDYLVKVVSEKEDEEIRDISELKLDVTELKQVLESLKDKIERIEYSVDNRLKLAENGEEKPFEEIFGGFQLVKLEW
>NC_021214.1|WP_004082347.1|1776577_1777240_-|type-I-B-CRISPR-associated-protein-Cas5
MKVLVFDVSAPYALFRRPYTTTSSYTLPFPPRTTLLGLVGCVLGYSTPERLDSAKVAVQIKNPLKFLRTGTNFVETKKDKKASKRTRISLQLLKNPAYRVFFSWEDEDFERLKNLLEHSETIFTPYLGVASFIARLNYVGKYEATRVADFPCEVHTVVPNTVKLLPEPSHYLIFERVTRKMDKERNMLESAVYIFKRDLSPVKVEGGEVWRVGEQNIVWM
>NC_021214.1|WP_015646196.1|1774421_1776587_-|CRISPR-associated-helicase/endonuclease-Cas3
MDVMKSHPDRRLIDHLEGVKRRSLEKFRSLDLSWEELFGYDENVLEEFVSLLSESHDVGKSTIYFQKHLSGERVERSLSAHALFSAVAFFHRSKNLPDKLRIFGFEIIRRHHGDFRNFLDIEIDEKVLEKQFSAIPEDFLRRYDLHDLKLSETIERIKRSISKFSILGKKDLSDYFLIHLFMSILVSSDREDVVFKSEPLPSLPSYEKEKILSYREKLGRKNQIDSLRWKFQEEILSFKPERGKIYSITAPTGIGKTIANLLFASHLADEDTIVIYALPFINIIEQTVDKIKEIFETESPFFVLPFHHLANPAYEEPDKYEDLLMNLWHSRVVVTTFVSLLESLITFRKIPFFYKFPKAVLILDEVQAIPHEYWTPVEKTVEFLSKMGTTVLLSTATKPALLKEALEVVSNKNVYFTALNRTVLKVEKEMSFEEYKEFVRETLKDGKRTLIITNTIREAEEIYDVVEGMGKTCFLSSRVIPKHRLEIVSKINEYDLCVSTQVVEAGVDISFERVIRDIAPVDSIVQAAGRCNRHFELEKGEVIVVPVRNERKNTLFSSYVYGSFLTETSMNVLKNHKFLEESEFFMLVEDFFSYVKTYGNPDKKGIGKALENLNFKKIGEFSLIEPEPTVPFIVLVDEEAQRVFEEFAEIFSGKRSRENFSLVKSLFRELSPYIVSARIKRDLPFPHTIAGMMVIHRNVLDKWYHPVKGLRVEGSDEVIII
>NC_021214.1|WP_004082345.1|1773945_1774425_-|CRISPR-associated-protein-Cas4
MMISGSVVLSYINCKREAWLMAHGVLPDQGNMHIEIGRFIHEDYSDSVMLPGMKIDTMFEREGVRVVGEVKKSSASKRGAEYQLLYYLYRLEEKGVKARGEIIVPKENKRIPVELTEENREKIKKVLEEVSSLLEEETPPPPKRKGICRKCGYELFCFS
>NC_021214.1|WP_004082344.1|1772976_1773936_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MESVYLFSSGTLKRKANTICLETESGRKYIPVENVMDIKVFGEVDLNKRFLEFLSQKRIPIHFFNREGYYVGTFYPREYLNSGFLILKQAEHYINQEKRMLIAREIVSRSFQNMVDFLKKRKVRADSLTRYKKKAEEASNVSELMGIEGNAREEYYSMIDSLVSDERFRIEKRTRRPPKNFANTLISFGNSLLYTTVLSLIYQTHLDPRIGYLHETNFRRFSLNLDIAELFKPAVVDRLFLNLVNTRQINEKHFDEISEGLMLNDEGKSLFVKNYEQALRETVFHKKLNRYVSMRSLIKMELHKLEKHLIGEQVFGSEE
>NC_021214.1|WP_004082343.1|1772707_1772971_-|CRISPR-associated-endonuclease-Cas2
MYVIMVYDVNEKRVAKILKIARKYLKWVQNSVLEGELSPGKYEKLKLEVSRLIDEKEDSVRFYVMDSQKVFNLETLGVEKGEDGFIF
>NC_021214.1|WP_004082342.1|1771395_1772724_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MASSSEGVSVLEIECKVVTPMFSRGAAEPKWENGNRVYPFELRPQSIKGVLRFWFRAIAPTVIDIYSLEGLENLSKKEKERWEKEKYKGLKYLEGLIFGSQERKSSFSLEVKVEGESQALGKYMNNRFSFTDDRLKDTKYALYGLYDKSGIYEYLQEGKNFIIILQTANDSIKGIILSLLKLVSTFSGFGAKTRKGFGEFEIVDPKLTRNDYNLVISECQEHIREFVNHHNSSSKVKIKLGRTNFNGIPDFPCFCDYKIFEITKFSGNSPLEVLREVFKVGRNFKGWYPSLKQKMRFSEGDCVKDLVEALEGLLKGRKTEKKIEIPTAVVGLPIQYQNLGRGEIRRLKVIVSSSLRGLGIDDIDGRKASPLFLSVHEGERGKWKLVVLLMRSRVTNDGELITEVKGGKTPSSGIKTIVKEEKDYKNLLEWIKKLGGKEIQGG
>NC_021214.1|WP_004082341.1|1768990_1771393_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MSKREEFWKSKITALLHDPLVKAFDVKNHENIAGEILKTLGIKKTRGEEDRLASAMDRFPIPYEKDAKKQIHVSFDETLFVHPFSGEGLPEVKSFFQNQKVEEMKSRLINALTKLKEKNDTYEKLFHSIWWNLPYILEGSQFLPADTRIANHSIIDHLDVTSALKGCVEGKQVKASLVAVAIGPVQEVIAQARKVKDLWAGSYLLSYLIYGAIEVVGKKYGFDSIISPYLRGNYFVKETLESMGVDLEDLCPVPPRREVASLPNLFVAIVPSSDEEILKECEEAIRNRWKTIVDETKEKLSKSEFLFNEHSFDYQSSLFPDIQTSKVSFDEPERIVETVRNLFTGSGIEDFKEVLKKVSEHAGYKENPGTFYRYLHRLLTSKLAARKMARLFPGYEEDVYPDHFTDADDFGAGVRACAVFKDKDIEKDIEKEDRLGTLNTVKRFLPEILNIRIKFDSTTDVARNNQANKEIEDPEKFKNGYIAVLLMDGDRMGDWMLGENAPFLEKVINPKVIEMFQETDDLKYAWEKLKEFKTIQPAYHRGVSRTLGIFSQLVGKIVDRHNGMLVYSGGDDVLALLPADSVLECANDIRKFFSGHLEYEIEIESGSDVERFRSENGVLYHNDKPFAPLMGRAATMSAGIAIVHHKFPLQVALKIAREAEKRAKNVYGRNAFCVTQVKRSGQMIFAGSTWEIEEEDVVKRSLKILEEMKNYNVSHRSLYKLLSPDFSLYEDKMEKFVEFTLRRSIHSEKSKNEFIGNFKNFLSRLLAYYKNTKKSSFDEAMREALELLIMVYSMKRGESQ
>NC_021214.1|WP_004082340.1|1768001_1768994_-|type-III-B-CRISPR-module-associated-protein-Cmr3
MKLWAIYFEPEDWVGFRETRRFSFSDRVESVFPSSFPFYGAVRTALLMKNQKFDPGDVERAGDVRMFGPFVFENTPEGRKHYFPLPRNIYKTDSGYRVTPIVEIDGVYLPWKPEYKMDSKESTSGGLIELSDLELLRSNTQGVCKFDLVSAEKIFKKETHIGVAFEENRKKVKERMIYSISYYRFYDGGFFMFTDDERTVELVSKLDGVFLGMKSKWSAVEVEELNTTAFDPPDYKNVAVALITPAVFDGGGMPKDKTILGKRVLTTAGIRKQVVSGWDLRENKPKKIYHAVSPGAVYYLEGKVNGHVLNESKFTDFGFGRCIFMKYEKL
>NC_021214.1|WP_004082350.1|1781352_1781703_+|J-domain-containing-protein
MNPYEVLGVPPGASKEEIEKAYRELVKKYHPDRYKDHPLKDLAEEKMKQINEAYAVLMSGEFSETPGQENVHNTFYSMGYRYRGNDGCRDILACLGCAWCTDTCCEACGGDCIPCM
>NC_021214.1|WP_008194418.1|1781693_1782164_+|hypothetical-protein
MHVKKVTYGGLVSALVVLLLYIGNFTKSKIFFAALSSVFTGVLVELFGIGSVPIIIAVNVLVFLLVPNPGYVLLFFVLSFYGFLRKKPILIRFLYLNASTLLLVFVASKFFNAELPDVSFSLYVLGFLGVQVAFFVYDYLYNRILQELLRIIRRKN
>NC_021214.1|WP_004082352.1|1782163_1782979_+|hypothetical-protein
MFGYIKPLKCELKVKEYEEFRGYYCGVCKALKKYSIIPRFLLTYEAASLGLLLSSLNNSDLKRKKELCIFTLKKVDFYSSSEIDEVARVFTALLREKLKDNYIDRKNPVYLFASAFLKKDPEISSLFENFYEMEKKEQDFKILAEEQGKIVGTILSKMVKEETQRKILYYLGLSLGKWLYIVDALDDFEKDKRKNVFNPLVKKYNGDLEKARSELRPHLKKCIDEMWKAYDLLDIKRNKTILDNIVYLGIPFITENVLVGKTCNLNHSTIL
>NC_021214.1|WP_004082353.1|1782960_1783536_-|hypothetical-protein
MVGRFPIYVEEEFTSDEKKWEFVLSKIESIDPAVASFVEEAPDGTMRVIGPFRARSGYALVISSPLSSLFHFLVLNVPRVLNAVVKPGRAYVEIYEKRDLFDSPGVFTLKVKGAKGFSLKQLKEDMKLFLGVEVEPAFQPVSLRNTKNGVIVTLKTLTPETTALVKLSRLCGTGESRKYGHGDVEIYRIVE
>NC_021214.1|WP_004082354.1|1783508_1784648_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MKVTLKTLTPLHIGSGEKYPPCNLVVLKEEENKKTAVRLITRKFLEVLRKHPEIKQNISENISKPLSFKEVENVEDGVFYEVSLYSDFSSGKKNPEIPEVVHHPDGSVYVPGSSLKGAVRLALTWHVLRNNRNLLEEFRRNVQKDLQNHKRAFYQTNEFLNGLFRFAPKEINTDYFRFLRVSDSQTLRTQLVVHDVGIFYVARPNTHPRTFPLEFVPINRDFVFDVRFVKEEYDYFLTHVRKRYGVELPGSIEEIFSIVNEFYSEVFKFERERFKKAKENFEKLDTSKIEERFQKIEKVLQSKKYVLIHIGYGGGLMANSLFILLDEETRKQVRNIIKYHKDDEAPLTRRYLVQSENNSYRVISPIGWCALWLEDSQST
>NC_021214.1|WP_174269897.1|1784644_1785502_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MKMSFRSGFRVGRGNETDSTLPTIHSDTIYGAVVYHAFKWSEKAEDFAKKLKVSSLLFVRGDRLLVPKPFLYNTYSLEEDDEESPKELKKASYVFLDKLADYRSIKEASGAVCKENPVEIVRIPRNSLDRITSSSNLYFVEVAFVKEGFTPAFLAEFPDEYEGLFKTAVKSLGDSGIGADSTYGYGLFNAEFESAPDFPEEGEYYLTLSLFVPSAEERSKMNEGYYRVVKRRGVKRDEMKVKKEISYVQEGSVFPFKPEGRGVLKIEDYFVQTSPLCVAFGGDGK
>NC_021214.1|WP_004082356.1|1785519_1786263_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MERPILGKYIIKGKIILETGLRIGGQELGVNIGGIDNPVIRNPLTGEPYIPGSSVKGKMRSLMERLLNLDISGNKVRRHECEERECKVCRVFGSTSKEGNNIPSRLLVRDAFLTEDSKTKLLSMETDLPYTEWKTENALDRVTCKADPRSFERIPAGAEFEFEIIYTAENEKHIKEDLENIATALELLEDDYLGGNGSRGYGKVKFSIEKVIFKSADYYKGEGTPVEKEVKGGVEGFKKAIPEIVKG
>NC_021214.1|WP_004082357.1|1786276_1786699_-|type-III-A-CRISPR-associated-protein-Csm2
MAVSQGVSLKEDLKDLVRKAEEIGRELSGKLKTNQLRKFHGHLTKIWSNYIYKKKDYRDNPEKFNEEILNELHFMKIFLAYQVGRDIEGISELKEILEPLIDEIKTPDEFEKFKKFYDAILAYHKFHSESEKSNRRTARR
>NC_021214.1|WP_004082358.1|1786713_1788867_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MKDREELVVGALLHDIGKVVRRAGDDRRHQIAGYDFTNKVKKFAVIQDYIHYHHEKDLLKKSLENEKVWYVCFADNLSSKERMTEDQKFEELRRMVNLLSKIPEGESSRNVTYFPAKPANEVVEAVKDMKEDQKTYEDLYRRFVEDAQKISPTPDDVNFLTYKYFSFIPQETRVEGDMDISLYDHLKVTAMLALSLYDYAKENDLKFESYQEMKSHFENSNVKPFLLVGGDVSGIQNFIANVSSKGALRSYRGRSFFIEILQEVVVDEILDKTGFYRTNVHFIGGGHFYLVLSNTEKVKKALEEIRNELNEWFRNRGLSLHLVIESVEFSVKDVEDMSKVFKKIGEKLNERKYRMYTEKDLEAIFPDDLNLIQEKGNHTCKICGNRVDKLFSIREGEEEIACDFCKEMYELGRELLEESHVYLAERKNGKFEIFKRKFDFSREPGEGFSYKLRRIYEFSEKEKNVRRIQVVTYFKEQEFEKIAEKAPGKKIASLLVDVDNLGKIFLKGLKKKTLSRYSTLSRLMSFFFKERVESIVEGKNVMVIYSGGDDLYLVGGWNDVLDVAKELREAFGRFTTNDFMTFSAGYVITDEKTSMSLIREMSERAESAAKKSGKNSIAFSNRNYYAVKWNTFFEMYNFYQELKEIADKVDRSVIRKALNLTREESPLNKAFLAYIEARENKDEDKRVANLMRENIDHLGENALNVILQFVDLLSRKS
>NC_021214.1|WP_004082359.1|1788887_1790534_-|CRISPR-associated-DxTHG-motif-protein
MGEVVKLVTFLGLGKYEESEIKINGNLLDGCVKNDDSQDIFCVRQSIFPLALIEYLNHIGKQVETIFFLTKTVKESKTWDECRRFLRSNIKDFEIPEGESSSNLMNFLVRNLVENLEEGDRVILDVTHSFRSIPLMASVVALYLKEAKDVNVSVVYGKYNKETKVTECEDLTPLTKATSWIYAVRLFKEYGYAKELADLIKKRNEEIYRRSQSSKKPKLLGSMSQKLQDLSSSIRLGSIVAIRKNLTNFFNFIDRNKARIREETEVFVPEIAALLDGIEKRYRVIHVKSENFELSEKELESEKELLDFYLQTGDLGMALRLAREYLINVYLMSGGEKSDFLDRNVRESVSISTFGYDTILQARNHVAHFGFNKLQLPSLKKIEDHLKVLVQTPPEQLLESARKTQRNRKRALLTPLGTTKGALYTVLKKISPDLLLVITSKQGKAILSEILEKAEFKGEFRVILLEDPFMGVSEIDRVVSEIKEHLSDVDEVIVNLTGGTTFLTYVIERAKNQIRYGRKVKTILAVDKRTYEEQKQNPFVVGEILELD

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_021214_8	8.3|1779987|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR	1779987-1780023	37	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	996115-996151	9	0.757
NC_021214_1	1.19|1640|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT	1640-1676	37	MF417888	Uncultured Caudovirales phage clone 9S_3, partial genome	37048-37084	10	0.73
NC_021214_7	7.2|1631904|34|NC_021214|CRT	1631904-1631937	34	NZ_CP034185	Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence	294235-294268	10	0.706
NC_021214_8	8.3|1779987|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR	1779987-1780023	37	NZ_CP010858	Marinovum algicola DG 898 plasmid pMaD3	115273-115309	10	0.73
NC_021214_1	1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT	1244-1278	35	KY554775	Lactococcus phage AM11, complete genome	48564-48598	11	0.686
NC_021214_1	1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT	1244-1278	35	KY554773	Lactococcus phage AM8, complete genome	48561-48595	11	0.686
NC_021214_1	1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT	1244-1278	35	KY554768	Lactococcus phage AM1, complete genome	48791-48825	11	0.686
NC_021214_1	1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT	1244-1278	35	KY554769	Lactococcus phage AM2, complete genome	48788-48822	11	0.686
NC_021214_1	1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT	1244-1278	35	KY554770	Lactococcus phage AM3, complete genome	49165-49199	11	0.686
NC_021214_1	1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT	1244-1278	35	KY554776	Lactococcus phage AM12, complete genome	48545-48579	11	0.686
NC_021214_1	1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT	1244-1278	35	KF926093	Lactococcus phage phiL47, complete genome	52499-52533	11	0.686
NC_021214_1	1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT	1244-1278	35	KY554774	Lactococcus phage AM9, complete genome	48562-48596	11	0.686
NC_021214_3	3.3|396732|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT	396732-396768	37	MH271312	Microbacterium phage RobsFeet, complete genome	48027-48063	11	0.703

1. spacer 8.3|1779987|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 9, identity: 0.757

-ttgtttttggcatgctggcgctggcgctggcgggcgc	CRISPR spacer
accgcgtct-gcatggtggcgctggcgctggcgcgcgg	Protospacer
 ..*. *.* ***** ***************** *** 

2. spacer 1.19|1640|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT matches to MF417888 (Uncultured Caudovirales phage clone 9S_3, partial genome) position: , mismatch: 10, identity: 0.73

ctactatcttctatatatatatttttgtttttgtttt	CRISPR spacer
agaaaacattctacatatataattttgtttttgtcct	Protospacer
  *  *. *****.******* ************..*

3. spacer 7.2|1631904|34|NC_021214|CRT matches to NZ_CP034185 (Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

agacgttcctgtcgctggtagtgtcga-atattcg	CRISPR spacer
ctacgttcttgtcgctggtggtgtcggtgcgctc-	Protospacer
  ******.**********.******. ....** 

4. spacer 8.3|1779987|37|NC_021214|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010858 (Marinovum algicola DG 898 plasmid pMaD3) position: , mismatch: 10, identity: 0.73

ttgtttttggcatgctggcgctggcgctggcgggcgc	CRISPR spacer
cgcatcttgccatgccggcgctggcgctggcggtggt	Protospacer
.   *.*** *****.*****************  *.

5. spacer 1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT matches to KY554775 (Lactococcus phage AM11, complete genome) position: , mismatch: 11, identity: 0.686

taaacttgtaaatccttttgaagacttagaacaac	CRISPR spacer
agaatttttaaatccttttgaagacttattgtcta	Protospacer
 .**.** ********************  ..   

6. spacer 1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT matches to KY554773 (Lactococcus phage AM8, complete genome) position: , mismatch: 11, identity: 0.686

taaacttgtaaatccttttgaagacttagaacaac	CRISPR spacer
agaatttttaaatccttttgaagacttattgtcta	Protospacer
 .**.** ********************  ..   

7. spacer 1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT matches to KY554768 (Lactococcus phage AM1, complete genome) position: , mismatch: 11, identity: 0.686

taaacttgtaaatccttttgaagacttagaacaac	CRISPR spacer
agaatttttaaatccttttgaagacttattgtcta	Protospacer
 .**.** ********************  ..   

8. spacer 1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT matches to KY554769 (Lactococcus phage AM2, complete genome) position: , mismatch: 11, identity: 0.686

taaacttgtaaatccttttgaagacttagaacaac	CRISPR spacer
agaatttttaaatccttttgaagacttattgtcta	Protospacer
 .**.** ********************  ..   

9. spacer 1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT matches to KY554770 (Lactococcus phage AM3, complete genome) position: , mismatch: 11, identity: 0.686

taaacttgtaaatccttttgaagacttagaacaac	CRISPR spacer
agaatttttaaatccttttgaagacttattgtcta	Protospacer
 .**.** ********************  ..   

10. spacer 1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT matches to KY554776 (Lactococcus phage AM12, complete genome) position: , mismatch: 11, identity: 0.686

taaacttgtaaatccttttgaagacttagaacaac	CRISPR spacer
agaatttttaaatccttttgaagacttattgtcta	Protospacer
 .**.** ********************  ..   

11. spacer 1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT matches to KF926093 (Lactococcus phage phiL47, complete genome) position: , mismatch: 11, identity: 0.686

taaacttgtaaatccttttgaagacttagaacaac	CRISPR spacer
agaatttttaaatccttttgaagacttattgtcta	Protospacer
 .**.** ********************  ..   

12. spacer 1.13|1244|35|NC_021214|PILER-CR,CRISPRCasFinder,CRT matches to KY554774 (Lactococcus phage AM9, complete genome) position: , mismatch: 11, identity: 0.686

taaacttgtaaatccttttgaagacttagaacaac	CRISPR spacer
agaatttttaaatccttttgaagacttattgtcta	Protospacer
 .**.** ********************  ..   

13. spacer 3.3|396732|37|NC_021214|PILER-CR,CRISPRCasFinder,CRT matches to MH271312 (Microbacterium phage RobsFeet, complete genome) position: , mismatch: 11, identity: 0.703

tgatccagacggcattcgtcctgtactgagctggaag	CRISPR spacer
tgatccagacggcgttcggcctgtacaagggctactg	Protospacer
*************.**** ******* ..* . .  *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	311058 : 318018	7	Streptococcus_phage(33.33%)	NA	NA
DBSCAN-SWA_2	1110716 : 1119435	8	Erysipelothrix_phage(16.67%)	NA	NA
DBSCAN-SWA_3	1270505 : 1288426	16	Synechococcus_phage(25.0%)	NA	NA
DBSCAN-SWA_4	1643407 : 1651020	10	Bacillus_phage(33.33%)	NA	NA
DBSCAN-SWA_5	1798317 : 1806260	10	Staphylococcus_phage(37.5%)	protease,transposase	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_021214|311058:318018|DBSCAN-SWA
TGTGGATGAACTCCTCGAGAAGGCGAAGAAGGTACGAGAGGCTTGGGATGTTCTGAGAAACGCTACGACGAGGGAAAAGAACAAAGCGATAAAGAAGATAGCCGAGAAACTCGATGAGAGGAGAAAAGAAATCCTCGAAGCGAACAGAATCGACGTGGAAAAGGCCCGCGAGCGGGGTGTGAAGGAGTCTCTCGTTGACAGACTCGCTCTGAACGATAAAAGAATCGATGAGATGATAAAAGCGTGTGAGACGGTGATTGGACTGAAAGATCCCGTGGGAGAAGTGATCGATTCTTGGGTGAGAGAAGACGGACTCAGAATAGCGAGAGTGAGGGTTCCCATCGGTCCGATAGGGATCATTTACGAATCCAGGCCGAACGTCACCGTGGAGACCACGATCTTGGCCTTGAAGAGCGGTAACACCATACTGCTCAGGGGCGGATCCGACGCTTTGAACTCGAACAAGGCGATAGTCTCAGCCATAAGGGAGGCGCTCAAAGAAACCGAGATTCCGGAAAGCTCCGTTGAGTTCATCGAGAACACCGACAGATCCCTCGTTCTTGAGATGATACGGCTCAGGGAATATCTCTCCCTTGTCATTCCACGTGGTGGATACGGCCTCATCAGCTTTGTGCGTGACAACGCGACCGTTCCGGTACTGGAAACAGGTGTTGGAAACTGTCACATCTTCGTCGATGAGAGCGCCGATCTGAAGAAGGCTGTTCCGGTCATAATAAACGCGAAGACACAAAGGCCTGGTACCTGTAACGCTGCAGAGAAACTGCTCGTTCATGAGAAGATAGCGAAGGAGTTTCTTCCTGTGATCGTGGAGGAGCTGAGAAAACACGGCGTCGAAGTGAGAGGCTGTGAAAAGACCAGAGAAATCGTGCCGGACGTGGTACCGGCTACTGAAGATGACTGGCCCACCGAGTATCTGGACCTCATCATCGCCATCAAAGTGGTCAAGAATGTGGACGAGGCGATTGAGCACATAAAGAAATATTCCACAGGACATTCCGAATCGATTCTGACTGAAAACTATTCGAACGCTAAAAAGTTCGTTTCAGAAATCGATGCCGCAGCCGTTTACGTGAACGCTTCGACCAGATTCACAGACGGCGGGCAGTTCGGTTTCGGTGCCGAGATCGGAATCAGCACCCAGAGATTCCACGCAAGAGGTCCCGTGGGGCTCAGAGAGCTCACCACGTACAAATTCGTCGTTCTTGGAGAGTATCATGTGAGGGAATGATTATGAAAGTCGTTGTAAAGGTTGGAAGCAACCTGCTTGTGGGAAGTTCTGGCTTGAGAAAGTCTTACATCGCAGAACTCTGTCGCGAGGTTGCACGTTTGAAAAGTCAAGGGCACGAAATTTCCATCATCACATCTGGGGCCCGCGCTGCGGGCTTTACTTATCTTGGAAAAGGAAAGAGAACACAGGACCTTCACATAAAACAGGCTCTCTGCGCTGTGGGACAGGTCCAGCTCATGAAGGTGTACGAAAACGCCTTCGATTTCTATGGCATCAAAATCGCCCAGATCCTGCTCACAAGGGACACTTTTTCCAACAGAAAAAGGTACCTGAACCTCAGAAACACACTGATCGGACTCTCGGAGTTCGATGTTGTACCCATCGTGAACGAAAACGACACAGTTGCAACAGAGGAGATCACACTCGGTGACAACGACACGCTCGCTGCCATGTTCTCGATAGCCTGGGATGCGGACTTCCTTGTGCTTTTCACAACGGTGGATGGAGTCATCGATGAGAACGGAAAACTCGTCGAAAGATTCGACGAGTCGGTGAAACTGAAAGATATGGGAAAGAGCAGCTGGGGAACTGGTGGTATCAGATCCAAGATAGAATCTGCGTTGATGGCTTCAAGATGCGGTGTGAAAGCGACCATATGCAGCGGAAACGACGTTTCAAACCTCACAAGGTTTGTGAAGGGAGAACCTGTCGGTACTGTTTTTGAACCACAAGGACGCTTGAAAGCAAAAAAAGCCTGGATTGCCTTTCTCTCAGAACCTGCAGGAAAGATATACGTAAACAAAGGAGCTGAAGAGGCACTCAAAAGCGGTAATAGCCTTCTGCCTGTTGGTGTCACAGGTGTGGAAGGAACGTTCGATGTGGGAGATGTGGTGGAGATAGTGAACGAAGAAGGAGAACTCGTCGGTCGAGGGATCGTGAATTACTCGTCTTCGGATCTGGAGAAAATAGCGGGTCACAAATCTTCCGATTTGAAAAAGATCCTCGGATACGAAGGAAACAAGGTGGTCGTTCACATAGACAACATGTGGGTAGCTTAAAAAAGCCCGCCGGGTGGCGGGCTCTTTATTTCTTCAGGTTCTCCAAATACTTTTTCCAGTCTTCCATGAACCTTTCTATTCCAAGATCCGTCATCGGGTGTTTGAAGAGTTTCTCCAGCACGGCAAATGGCATCGTCACGATATCCACACCCATAAGTGCTGCTTCCACCACGTGCATTGGATGTCTGATGCTTGCGGCGATGATCTCGGTTTCGAAACCGTAGTTGTTGTAGATCTCGACGATTTCTCCAAGCATTCTCATTCCGTCGTTTGAAAGATCGTCCATCCTTCCAACGAAGGGGCTCACGTAGGTTGCTCCCGCTTTCGCGGCCAGAATGGCCTGGGCTGGGCTGAACACGAGTGTCACGTTTGTCTTTATACCCTCTGCAGAGAGAGTCTTCACCGCTTTGATGCCATCGGGTGTCATTGGTATCTTGATCACCACGTATTCGCTGATCTGAGCGAGTTCTCTCGCCTCTCTCACCATGCCTTCGTAGTCGAGAGACACAACCTCCGCAGAAACGGGACCTTTCACCAGATCGCAGATCTCTTTCACTCTCTGTTTGAACTCTGCTCCTTCCTTTGAAATCAGTGTTGGATTCGTCGTTACTCCATCCACGATACCCCATTCAACACCTTTTTTGATCTCTTCTAAGTTTGCTGTGTCCAGAAAGATCTTCATCGTTTCACCTCCCAGAAGCTATTCTCTCTTATTTTCTTTAAGAGCTCGATAGGAGTTTTTGAAAATCTCTGTTAGTCTTTGGTTGATAAGAAGTTAACTCAACGTTCCTGATTTGATAGAAACATTTCAACTTCATCTAACACCGGCATAGCATCTACACCGCCTACTCTTGTGATAACGATAGCGGCGACGGCGTTGGCGAACTTTCCTATCTCGACAGCGTCTTCGATCGTTTCAGGTGTTTTCTCCAGATACTTGTGTATCACAGCGGCTGTGAACGAGTCTCCGCACCCCGTGGCATCCACAGGTTTTACTTTGAAAGAAGGAACCATACGTTTTTCTCCTTTGAACTTCACAAGACATCCCCTTTCTCCCATGGTCACAAAAAGCAGGCCGTTTTCCTTGATCGGAATTTTGTCAACGGCCGTTTCTAAATCTTCCTGGAAGATGTATTCCAGATCCTTGTCGCTGAGTTTTACGATATCTACCTTCGAAGAGATCTCGAGAAAGTCCTTCACGAAGGTGTTTCTGTCTTCTATCAGTGAGGGTCTCACGTTCGGATCGTAAGAGACGGGCTTCCCTTCTTCCAAAAACGTTTCCATCACTTTCAAATAGGCGCTTCTCGATGGTTCAACGGCAAGAGAGTATGATCCGATGTGAAGGAAAGAAAATTGTGCGGGGTCGATGTTCACTTCTTCCGGTCTCAGATTCGTATCGGCTGGTTTTTCTCTGAAGAAGACGAAATCCGGATTTCCCTGAGCGTCTCTTGCCACAAAAGCGAGGGTAGTCTTACAAGAAGAATCGAAGATGATGTGTGTTGTGTCTATGCCTTCTTTTTTCATCACCTCAAGTAGGAACTCGGAGAACTGGTCTCCTCCAAGTTTTCCGAGAAAAGAAACCTCTCTTCCCAGTCTTTTGAGAGCAACGGCGACGTTCAGGGGAGAACCTCCCGCTTTCTTTCTGAAGAGCTCACTCTGTGAAAGGTTCTTTCCTTTGTCCTCTGAGATGAAATCAATGAGGATTTCACCGGTGCAGAGAACATTCACAAGAATACACCTCCGCCGGAAAACGATTTTCTATTTCATCTTCATTATACTTCAAGGCGAAGTGTGTTAATATTGTGTTGAACTGTTATTTTTCCGGGAGGGATCGTTGTGAATATTCTTGAAAAGCTTTTCTCTTTGAAAAGAAAGGTAGCTCTGGTGACTGGTGGAGGACAGGGCATCGGGAAGGCCATCGCCCAGGCGCTGGCAGCGGCGGGTGCAGCTGTTTTGATCATGGACATAAACGAAGAAACAGCCAGAAGAACGGTCGAAGAGATAAAAGAGAAAGGTGGCGAAGCAGATTTCTATGTTGGGGATGTGACGAAAGAAGAAGATTGTTTTGGAGCGGTCAAAAAGGCGCTGGATAGGTGGGGGAAACTCGACATAGGAGTCAACAACGCGGGAATAGGAGACTGGTGTGAAGCGGAGAATTATCCGGTTGAGAAGTGGAAAAAGGTCATAGACGTGAATCTGGTTGGGGTGTTTCTTTCCGCAAAAGCGGAGTTCCACGCTATGAAGGAAAGAAAATACGGAAAGATCATAAACATCGCGTCCATGTCCGGACACATCGTGAACAAACCTCAGAAGCAGACAGCTTACAACGCTTCGAAAGCGGGTGTGATCCATCTCACCAGATCTCTGGCCGCCGAGTGGGCCCCGTACGGAATCAGGGTGAACAGCATAAGCCCCGGATACATCAGAACACCTCTCATAGAATCTCCAAACGTGAAAGATCTTGTTCCCCTCTGGCTCGACATGATCCCTCTTGGAAGACTGGGAGAGGTGGACGATCTGATAGGAGCTGCTATCTTCCTTGCAAGTCCCGCCTCAGATTACATGACAGGGCACGATCTTGTGATAGACGGAGGCTACACCGTCTGGTGAGGAGGTTAGAATATGAAAGTACTTTTGATAGAAAAACCCGGTGTTGCGAGTGTTGTGGAGAAAGAGATACCCGTTCCCGGTGAAGATCAGACCCTCGTGAAAGTACTCGCGTGCGGTATCTGTGGAACCGACTACAAGATATTCTCAGGAGGCACCAACGCCAACTATCCAGTTGTTCCAGGGCATGAGATCGTCGGCGTCGTTGAAAGATCGGGTGTTTTCGAAAAGGGGCAGATGGTTGTGATCGATCCCAACAGATCCTGTGGGAAGTGTGACTACTGTAGAAAAGGTATGTCTCAGTTCTGTGAAAACCTTCAGGCAACGGGCGTGACAGAACCAGGAGGATTTGCGGAATACGTGCTCGTGGAGAACTCACAGGTTTATCCTGTGAGAAATGTACCCGCAGAGAGAGCCGTTTTCGCAGAACCGCTTTCCTGTGTTCTCGAAGGAGTGAAGATGGTGAAACATGGATTCTACGACAGAATCCTCGTAGTCGGAGCAGGTAGTATAGGTGTGATTTTTGGTCTGATCTTCAAGAAAATTTTTCCGGGTGCAGAAATAGTCCTTGCGGAGAAAGACGAGAAACGTGCGGAATACGTTGTGCAAACTTTTGGATTGAAAGTGGATGAACCAAAAGGAGAGTACGATCTTACTGTCGAGTGTTCTGGTACGGTGGAAGGGTTCAAAACTTGCTTTGAACACACAGGAAAAGGTGGAATGCTCCTTCAGTTCAGCGTCATCTCCAAAGACAAGATGGTTGAGATCTCACCGTTCGAGATCTACCGAAAGGAGATGAAAATACTCGGGTCCTATCTCAATCCTTTCACAATGAAAGAAGCGGTGAAGATCATAGAATCTGGAGAGTTTCCCTTCGAAAAACTTGTCACCGATCGTCTGGATCTTGAAGGGGTGAAAGAATACCTGTCGTCTCACAAAAAGGCATTGATGAAGGGAATTTTTTCTTAATTAAGCTAATTCCCGTCGAGAGTTTTAAAGAAAAACATTCTTGTCACGAGAAATCTTTTAGTGTTTTTATTGTTCTGACGGAAGATCGCTCCACGAATTTTACCTTTAACACAACTTGCATACGGGGAGATGGTTTCTTTCTATTTTTCATTCTGTCTAAAAGAATTGTTGCTGCTATCAACCCTATTTGTTGGGGGTCTTGTCTTACACAAGTTATCGGCGGATCGAAGATTTCGTTCCAATATGCATCATCGAAACTGACAAGGGATATGTCTTCTGGTATTTTTATATTCAGCTCCTTAGCAGCTTTTAATACTCCTAAAGTCATCAGGTTATTTCCAATGACAATAGCTGTCGGTCTTTCCTGACTTGTCATTATCCTCAGAAAGGATTCATATCCACCCTGTTCAGAGGATCTTCCGTCTCTTATCCACTCTTCGCGGATCTCTATGCTGTCCTTGAAGAGGAGAAAGCCCTTTAATCTTTCTTCTCCAGTAAAAGAACCTCTTAAAGGATGTATGAGACCGATTTTTTTATGGCCATGCTTTACAAGGTAATTAACAAGTATTTCCATTCCTTCTCTATTATCTGAAATTACAAAGTCAGAGTCTACACCTTCTACTAGCCTGTCGAAGAAAACCACGGGAATTTTGAAGTGATTGATTATACTGTTGTATATATCCTTATTTTCCTTCACATTCACAGGCGCAGAAAGAATTCCCTCTACTTTTTGATCGAGGAGAAGTTGTAAATGCTCCCTTTCCTTCACAGGATCGTCATCAGTTGAACAAAGTATAAGTCTGTATCCGAGATGAAACAATGATTTCTCTATACTTGAGACGATATCTGCGAAGAAATTAGCGCTTAACTCAGGTATGAGAACACCAACAGTTCTAGTATTTCCCTTTTTTAAACCCAGAGCCATTAAATTTGGGGTATACCCAATTTCTCTGGCTTTTTCCAGTATTTTCTCCCTCAATTCACTGCTGACACCGGGTTTTCCAGAAAGAGCTCTTGAAACAGTGGAAATTGAGACACCAAAATATTCTGCAATGTCTTTTAGAGTAGCTTTTTTCAT

Protein sequences of DBSCAN-SWA_1

>NC_021214|311058:318018|314144_315092_-|WP_004083014.1|DBSCAN-SWA
MNVLCTGEILIDFISEDKGKNLSQSELFRKKAGGSPLNVAVALKRLGREVSFLGKLGGDQFSEFLLEVMKKEGIDTTHIIFDSSCKTTLAFVARDAQGNPDFVFFREKPADTNLRPEEVNIDPAQFSFLHIGSYSLAVEPSRSAYLKVMETFLEEGKPVSYDPNVRPSLIEDRNTFVKDFLEISSKVDIVKLSDKDLEYIFQEDLETAVDKIPIKENGLLFVTMGERGCLVKFKGEKRMVPSFKVKPVDATGCGDSFTAAVIHKYLEKTPETIEDAVEIGKFANAVAAIVITRVGGVDAMPVLDEVEMFLSNQER
>NC_021214|311058:318018|312308_313364_+|WP_004083012.1|DBSCAN-SWA
MKVVVKVGSNLLVGSSGLRKSYIAELCREVARLKSQGHEISIITSGARAAGFTYLGKGKRTQDLHIKQALCAVGQVQLMKVYENAFDFYGIKIAQILLTRDTFSNRKRYLNLRNTLIGLSEFDVVPIVNENDTVATEEITLGDNDTLAAMFSIAWDADFLVLFTTVDGVIDENGKLVERFDESVKLKDMGKSSWGTGGIRSKIESALMASRCGVKATICSGNDVSNLTRFVKGEPVGTVFEPQGRLKAKKAWIAFLSEPAGKIYVNKGAEEALKSGNSLLPVGVTGVEGTFDVGDVVEIVNEEGELVGRGIVNYSSSDLEKIAGHKSSDLKKILGYEGNKVVVHIDNMWVA
>NC_021214|311058:318018|315986_316940_+|WP_004083017.1|DBSCAN-SWA
MKVLLIEKPGVASVVEKEIPVPGEDQTLVKVLACGICGTDYKIFSGGTNANYPVVPGHEIVGVVERSGVFEKGQMVVIDPNRSCGKCDYCRKGMSQFCENLQATGVTEPGGFAEYVLVENSQVYPVRNVPAERAVFAEPLSCVLEGVKMVKHGFYDRILVVGAGSIGVIFGLIFKKIFPGAEIVLAEKDEKRAEYVVQTFGLKVDEPKGEYDLTVECSGTVEGFKTCFEHTGKGGMLLQFSVISKDKMVEISPFEIYRKEMKILGSYLNPFTMKEAVKIIESGEFPFEKLVTDRLDLEGVKEYLSSHKKALMKGIFS
>NC_021214|311058:318018|315200_315974_+|WP_004083016.1|DBSCAN-SWA
MNILEKLFSLKRKVALVTGGGQGIGKAIAQALAAAGAAVLIMDINEETARRTVEEIKEKGGEADFYVGDVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSAKAEFHAMKERKYGKIINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLAAEWAPYGIRVNSISPGYIRTPLIESPNVKDLVPLWLDMIPLGRLGEVDDLIGAAIFLASPASDYMTGHDLVIDGGYTVW
>NC_021214|311058:318018|316983_318018_-|WP_004083018.1|DBSCAN-SWA
MKKATLKDIAEYFGVSISTVSRALSGKPGVSSELREKILEKAREIGYTPNLMALGLKKGNTRTVGVLIPELSANFFADIVSSIEKSLFHLGYRLILCSTDDDPVKEREHLQLLLDQKVEGILSAPVNVKENKDIYNSIINHFKIPVVFFDRLVEGVDSDFVISDNREGMEILVNYLVKHGHKKIGLIHPLRGSFTGEERLKGFLLFKDSIEIREEWIRDGRSSEQGGYESFLRIMTSQERPTAIVIGNNLMTLGVLKAAKELNIKIPEDISLVSFDDAYWNEIFDPPITCVRQDPQQIGLIAATILLDRMKNRKKPSPRMQVVLKVKFVERSSVRTIKTLKDFS
>NC_021214|311058:318018|311058_312306_+|WP_004083010.1|DBSCAN-SWA
MDELLEKAKKVREAWDVLRNATTREKNKAIKKIAEKLDERRKEILEANRIDVEKARERGVKESLVDRLALNDKRIDEMIKACETVIGLKDPVGEVIDSWVREDGLRIARVRVPIGPIGIIYESRPNVTVETTILALKSGNTILLRGGSDALNSNKAIVSAIREALKETEIPESSVEFIENTDRSLVLEMIRLREYLSLVIPRGGYGLISFVRDNATVPVLETGVGNCHIFVDESADLKKAVPVIINAKTQRPGTCNAAEKLLVHEKIAKEFLPVIVEELRKHGVEVRGCEKTREIVPDVVPATEDDWPTEYLDLIIAIKVVKNVDEAIEHIKKYSTGHSESILTENYSNAKKFVSEIDAAAVYVNASTRFTDGGQFGFGAEIGISTQRFHARGPVGLRELTTYKFVVLGEYHVRE
>NC_021214|311058:318018|313389_314046_-|WP_004083013.1|DBSCAN-SWA
MKIFLDTANLEEIKKGVEWGIVDGVTTNPTLISKEGAEFKQRVKEICDLVKGPVSAEVVSLDYEGMVREARELAQISEYVVIKIPMTPDGIKAVKTLSAEGIKTNVTLVFSPAQAILAAKAGATYVSPFVGRMDDLSNDGMRMLGEIVEIYNNYGFETEIIAASIRHPMHVVEAALMGVDIVTMPFAVLEKLFKHPMTDLGIERFMEDWKKYLENLKK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004083010.1|311058_312306_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.2e-106	49.2
WP_004083012.1|312308_313364_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	6.4e-48	38.3
WP_004083013.1|313389_314046_-	fructose-6-phosphate aldolase	I3ULK3	Synechococcus_phage	6.8e-48	45.6
WP_004083014.1|314144_315092_-	carbohydrate kinase	NA	NA	NA	NA
WP_004083016.1|315200_315974_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.0e-18	30.5
WP_004083017.1|315986_316940_+	zinc-dependent alcohol dehydrogenase family protein	M1PHA2	Moumouvirus	3.6e-13	26.8
WP_004083018.1|316983_318018_-	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	2.5e-28	27.4

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_021214|1110716:1119435|DBSCAN-SWA
GATGCTGGAGCAGGTGAGGATACAGAAGATGGTCAACGGAGGTTACGGCCTTGCCCATCTTTCAAACGGCAAGGTAGTTCTCGTAGAAGGAGCATATCCCGGTGAGGAAGTCCTGATAAAGACCTACAGAGAGAAAAGGGATTTTTCTTTTGGAAAGGTTGTTTCCCTTCTGAAAGAATCCGAAGATCGAATAAAACCACCCTGCAGATACTTTGGAAGATGCGGTGGCTGTCACTGGATGGATGTGAAGTATGAAACCCAGCTTCGTTACAAAAAGGAGGTATTGATCGATCTTTTCGAACGCTCAAATCTGAAGGTAGAAGTGGAAGATGTGGAGCCGAGTGATCTTGTTTTTCACTACAGGACGAAAATGGAGTTTCATTTTCAGGGGAGAAAATTGGGTTTGAAAAAGAGAAACTCCGATTTTGTGATTGACATAAAAGACTGTGAGGTGGCACCGGAAGGCACGGGTGAGATTCTGAACACTGTAAAAGAGGCCGTTCAGGTACTCAACGTTCCTGTTTACAACTGGGAAACGAGGAAGGGAGTGCTCAAGCACCTCGTGATCAGGTACGCATTCAGCACGGACCAGTTCATGGTGATCTTTGTGACAAAGACAGAATCCTTTCCCTGGGGAAGAGATCTGGTTCGCGCTGTGTTAAAGAGATTTCCAAAGATTCACTCCATCATTCATGTGATGAACTCTAAAGACTCTGTGGTCCTAAGGGGGCCGTACAAGACTCTCTACGGTGAAGGAGTAATTGTGGAAGAGTTCGACTGGGAAAGGTTTCAAATTCCACCGACCGCCTTTTTCCAGAGCAACTACTCCATCACATCCAAACTGATAGATCACGTGTACAGAGAACAGGCACTTCAGGGTAACGAGGTGGTGCTGGATCTGTACGCGGGTATCGGTACGTTTTCTGTGAGGACTTCCTTTTCGGCAGCAAGGGTGATCTCCGTTGAATCCAGCAGGGTCGCTGTGAAGGCTGGAAAGGCTAACGCGAACATAAACAGCAGAAAGAACATAGAATACGTGGAACAGGATGTGCTAGACTTTCTGAAAAACTACAGCGGAAGGGCAGACAGGATAATCCTGGATCCACCGAGATCAGGTGCGGGTCCAGAAGTGATGAAAGAAATAGCGAGACTTTCACCTGAAAGGATCGTTTACGTTTCCTGTGACCCTTCTACTCTGGTGAGAGACCTCAAGGTGCTGGTGGAAAACGGCTACTCTATTGTCAGGGTGAAGCCCTTCGACATGTTTCCTCAGACTTACCATGTGGAAACTGCTGTGACTCTCGTGAAAGGGGATCGATGATGTTAGGCCTGGGACTTTCTCTGATCTTCGCTGTTCTCTCGTGGAAAGACAGTGCTTTTGTATCGATACTCGCTCTTGTTGCTTCTGTTATTTTCTTCTTCACCAGAAGTGAGAGAGAAAAGACCCTGTTTCATGTGAGTCTGATCTTTCTCCTCGTCCTCGAGGGGTTCGAATATTTGAAAGGGACAGATTACGATCGAGCCGAGTTGTTTCTGGTGCTGTCCTTCTTTCCTCTGATCGCCACCAGTTTCGCAAAGAAAAAAACCGTGAACATACCTCTCAAATCGCTTTTCTGGTTTCTCGTTGCGATGGCGTTGTGGAAGGTAGCGAGCATTAAATATCCAACGGCTTCTTATCTTGTTTTTCCTGTTGTTGCGCTCGTGTTCACGAGAGATCTGTTTGGGAGGGAAAAAGATGGTAGAAAGGTATTCGCTGTCACCGATGAAGGATCTCTGGACGGAGGAAGCGAAGTACAGAAGATGGCTGGAAGTGGAACTGGCAGTGACGAGGGCGTACGAAGAACTGGGAATGATTCCGAAGGGAGTCACAGAGAGGATAAGAAACAACGCTAAGATAGATGTGGAACTGTTCAAAAAGATAGAAGAGAAAACAAACCACGATGTGGTGGCGTTCGTCGAAGGAATCGGCTCGATGATAGGAGAAGACTCGAGATTCTTCCACTACGGTCTCACCTCGTCAGATGTTCTCGACACCGCAAATTCCCTCGCTCTCGTGGAAGCGGGGAAAATCCTGTTAGAGTCTCTAAAAGAGTTCTGCGACGTGCTCTGGGAAGTCGCGAATCGGTACAAACACACTCCCACCATCGGAAGAACACACGGAGTCCACGCGGAACCCACCTCCTTTGGCTTGAAGGTCCTTGGATGGTACTCCGAAATGAAAAGGAACGTTCAGCGCCTTGAGAGGGCGATAGAGGAAGTTTCTTACGGTAAGATCAGTGGAGCTGTTGGAAACTACGCAAACGTACCACCGGAGGTGGAGGAAAAAGCGCTTTCGTACCTGGGCTTGAAACCTGAACCCGTCTCCACACAGGTTGTACCGAGGGATCGTCACGCTTTCTATCTGTCCACGCTCGCGATCGTGGCAGCGGGGATAGAAAGGATCGCTGTCGAGATCAGACATCTTCAGAGAACGGAAGTGCTCGAGGTGGAAGAACCGTTCAGGAAAGGTCAGAGGGGCTCGAGTGCCATGCCCCACAAGAAGAATCCCATCACCTGCGAGCGGCTCACGGGACTTTCCAGAATGATGAGGGCGTACGTCGATCCTTCCCTTGAAAACATCGCGCTCTGGCATGAGAGGGACATTTCGCACTCTTCCGTCGAAAGATACGTTTTTCCTGACGCCACGCAGACTCTTTACTACATGATCGTCACGGCCACAAACGTGGTGAGGAACATGAAAGTGAACGAAGAAAGAATGAAGAAGAACATAGATCTCACGAAAGGTCTCGTGTTCTCCCAGAGAGTCCTGCTGAAACTCATAGAGAAAGGACTCACGAGGAAAGAGGCTTACGATATCGTCCAGAGGAACGCTCTGAAAACCTGGAATTCCGAAAAACACTTCCTCGAGTACCTCCTCGAGGATGAAGAGGTTAAGAAACTGGTTACCAAAGAAGAGCTCGAAGAACTCTTCGATATCTCTTACTACTTGAAACACGTAGACCACATCTTCGAACGCTTTGAAAAGGAGTGAAGCGAATGAACCGTGTTGTGGTGGGTCTTCAATGGGGAGACGAAGGAAAGGGCAAGGTGGTAACGTATCTTTCCAGATATCACGATATCGTGGCGAGATTTTCAGGTGGAGCGAATGCCGGGCACACTGTGAATTACGGAGATTTCAAGGTGATACACCACCTCCTCCCTTCGGCCGATTTCACAAAAAACAGAGGAATCGCCATAGGAAGCGGGGTTCTCCTGGATCCTCAGGTGCTGACAGAAGAATTGAGGGAATTGAAAGAGAAATTTCCCGATTATTCAGGTGAAATCTTCATCTCTGAGAGCGCACACGTGGTTCTTCCAGTGCACAAAGAAATGGACAGGATAATAGACGAAGTGTTGAAAATAGGCACTACGAAAAGAGGAATAGGTCCCGCTTGTGCTGACAGGGTTATGAGGGTGAACGTGAGAGTTGCAGAGCTCGGCAACGAAGAAAAACTCAGATATTTCCTCGAAAAGAATCTCTCTTTGAAGAAGATCTACGGGGTGGATTTCGACGCAGAGAAAATGATGGGAGATCTTTCCACCTTCTATGAGACAATAAAAGACTTCGTCGTTTCACCGGTCCAGTTGAAAAGAATCCTCGAAGAGAAGAGCGTTCTCTTCGAAGGAACACAGGGGGTCCTTCTAGATCTGGACGTGGGAACGTACCCGTACGTCACGAGCATGAACTGTTCCTCCTCAGGCGTGAGCGCGGGAATGGGCTTTCCTGTGGAAGTAGATGAAGTTTTAGGCGTCTTCAAGGCGTACACAACACGAGTCGGAGAAGGTCCCTTCCCGACGGAGCTCACAGGAGAAGAAGGAGAGAAGTTGAGAAAAGCGGGACACGAATACGGTTCCACGACCGGTCGGCCGAGGAGATGCGGCTGGCTCGATCTGCCGCTCCTCAGGTACGCCATTGAGATCTCCGGTGTCGACTCTCTGGTCATGACCAAGGCAGATGTGCTGAACGGTTTTGAAAAGATCAAGGTCTGCGTGCGCTACTCCGATGGAAGAGATCTCGTTTCACTCAGAGATCTGGAAAAGAAAGAGCCCGTCTACGAAGTCTTCGATGGCTGGAAATCTCTGGAAGACAAGAACTTCGAGCGCTTTGTTGATTTCATAGAAAGAGAGACAGGAAGACCGGTAAGGTACATATCCACAGGTGAAAAACTCGAGGATATAGTGGAGGTGTGAAGTGTGTCTGTGAATCTGAAAGGGAGATCTCTTCTCACTCTTCTTGATTTTTCTCCTGAAGAGATCAGATACCTTCTCGATATCTCAAAGCAGGTGAAGATGGAGAACAGATCCAAACTGAGAACCGAAAGGTTCAAAGGAATGACCCTCGCCATGATCTTCGAGAAACGATCAACGAGAACGAGACTCGCCTTTGAAACCGCTTTTGCAGAAGAAGGAGGACATCCGATCTTTCTTTCACCGAACGACATACACCTTGGAGCAAAAGAATCTCTCGAGGACACCGCACGCGTCCTTGGAAGAATGGTGGACGCCATCATGTTCAGGGGCTACAAACAGGAGACTGTGGAAAAGCTGGCTGAGTACTCCGGTGTTCCCGTGTACAACGGACTCACCGACGAGTTCCACCCAACGCAGGCGCTCGCCGACCTGATGACCATAGAGGAAAATTTTGGCAGATTGAAGGGTGTAAAGGTTGTTTTCATGGGGGACACCAGAAACAACGTTGCGACCTCCCTCATGATCGCCTGTGCGAAGATGGGGATGAATTTCGTGGCGTGTGGTCCCGAAGAACTCAAGCCCAGATCTGACGTATTCAAAAGGTGCCAAGAAATAGTGAAAGAAACCGATGGGAGCGTTTCTTTCACATCGAATCTGGAAGAAGCACTCGCAGGTGCCGATGTCGTCTACACAGACGTGTGGGCATCCATGGGTGAGGAAGACAAAGAAAAGGAGAGAATGGCTCTTTTAAAACCTTATCAGGTGAACGAGAGAGTGATGGAAATGACGGGTAAATCGGAAACGATTTTCATGCACTGCCTCCCCGCGGTGAAGGGCCAGGAGGTCACCTACGAGGTAATCGAGGGAAAACAGAGCAGGGTCTGGGACGAGGCGGAGAATAGAAAGCACACCATAAAAGCGGTCATGATAGCAACACTGCTGTGAGGTGAAGCCGTGAGCGTTCTTTACTCAATAATAGCCCTTGCTTTGTATCTTGCGTTCATGTTTTCGATAAATCTCTTCAGGATACGCCGATTCGAGAAGGCGATCTTCTATCAGTCCCTGCTGGGACTCGCCGGCGCTGTGACGGTGTGTGTGGCCTTTCGATACGTTCCATCGTTCAGAGTAAGCTTTGTCGATCTACACTGGTTCCTGATTCTCCTCTTCGTGAACGTGTTTTTCTTAGGAGGCAGTGAAGTTCGATTTCCACCCTTCATGAACCGCTTCATCGTGATGGTTTCGGTGGTGTTTCTGTCTCCTTTCTCGGAAGAATTGTTCTTCAGGGGAGTTTTTTTGAAACTGAACGGAAACGACATATGGACCAACGCACTCGTTTTTTCTTTCCTTCACCTCTTCAACGTGATCGTGGGCTTCGAAAGATTTTCCTTTGCGAACCTCGTATACAGATTCGTCGTTGCACTCATATTCGCTCACAGCGCAGCCGTCAGTGGTTCTCTGTTTCCCGCTGTTCTGTACCATACCACCAACAATCTTGTCGCCTTCATCCTTATGACCAGGAGGGGAAGGAATGTTCATAACGTTCGAGGGAATAGACGGATCCGGGAAGAGCACACAGATCCAACTTCTGGCTCAATACCTGGAGAAGAGAGGAAAGAAAGTGATCTTGAAGAGAGAGCCGGGCGGAACGGAGACGGGGGAGAAGATCAGAAAGATTCTTCTGGAGGAAGAAGTGACTCCCAAAGCTGAGCTCTTCCTGTTTCTCGCCTCGAGAAATCTCCTTGTGACAGAAATAAAACAGTACCTTTCCGAAGGATACGCCGTTCTTCTTGACAGATACACGGACTCCAGTGTTGCATACCAGGGTTTTGGAAGAAACCTGGGAAAAGAGATCGTGGAGGAGCTGAACGATTTCGCCACGGATGGACTGATTCCTGACCTGACTTTCTACATAGACGTGGACGTCGAAACGGCCCTCAAAAGAAAAGGAGAGCTCAACCGCTTTGAAAAAAGAGAGTTTCTCGAACGTGTAAGGGAAGGCTACCTCGTGCTCGCCAGAGAACATCCCGAAAGGATCGTGGTGCTGGATGGAAAACGCTCCATAGAGGAAATCCACAGGGACGTGGTGAGGGAAGTTAAAAGAAGGTGGAAACTCGATGTTTAGAATAGCCATTGTGGAACTGAAGAGGATCTTGAAGAAAAGATCTTCACTGATGATGATAATCGCTGCACCCGTTCTGGTTGTGCTGATCTCTCTTCTCTTCATGCAGGGGTACAACCTTCAGACGATGAAGCTCGGAATATACAACGAAGACAACAGCATCTGGTCCTCCCTCGTCATGAGATTCATTGGAACCATCCTGAGACAGGAAAACATAGTGAAAGTCGATCAGAACTACGAGAAACTTCTGAAGGAAGGAAAGCTGAACGCGGTCATAGTGATTCCAAAGGGCTTCGCGGCGAAACTGTATTCCAAACAGCCAACCCAGATGATCTTCATCCCGAGTCCCATCGATCTTCACCTCGCCGCCGCGATATACAACGTTCTCGATTCTGTTCTGGCGGATTTCCAGGGGAGTGCCTTCTTCGATCCAAAGGTGCTCCGGTACATATTCACAGAGTCCGATTATCCCGTACCCAGATTGAAATTGAAAGACTCAGAACTCAGATTTTCTGATCTCATCTCCCCGTTCGTCGTCTTCTTCACGGCGATTTTGATAACCGTATCACTGGCGAGTGTCTCCACCTTTCTCGACAGAGAGAAGAACCTGCATGAGATGTTCCTCGTGTACAACCTTCCGGCATGGAAATACGCCTGCGGGAAGATACTCGCTTACACCATCATTGGAGCATCCGTTTCTTTCATAGCCTACTCCCTGACGGTGATACTGACCGGAGACAGCCTGGATTTCTTCATTACGTCTGTTCTCATCCTTCTCAACGCTCTTCTTCACACGTCTGTAGGTTTTCTGGTTTCTTCCATTTCTCCCGACAAGAGTCTTGCAAACATACTCGGTGTTTCTGTTATAGGAATATCCCTGTTCTCAAGCGGTTTTGCCATTCCTATAAGTAACTTGCCAGATATCTTTCGAAGAATCGCCATGTCAACGCCCGTGTTCAGAACCATGTACGCCCTCAGGGTGTACCAGCTGGAACATACCGTCGATAATCGCTCGATCTTTGTCGTCTTGCTCTGGACAGTTGTTTTGTTCTCCATTTCCATTCTATCGGGAAAGTTCGTTATCAGGAGGGGTTGACCTTGAGGATTCTTGTGATCTCGGATACCCACGGTTCACTTTCTTGCACAGAGAAAGCTTTGAAAAGTGCGGGGAATTTCGATGAAATCTGGCATCTAGGTGATGTTCTCTACCACGGCCCCAGAAATCCGCTTCCCGAGGGATACAGTCCAAAGGAACTCGCATCACTTTTGAAGAAACACCGTGTGAAGTACATACGCGGAAATTGTGATGCGGATGTGGATATAAGGGTTCTGGAAATTCCGGAAATGCCCAGGATCGGAATGGAATTTTTAGGAGATGTGAAGATACTCCTTGTTCACGGCGACCAGTTCGAATACGAAGGAGGAGATCCTGTGAGCCTGGCACAGGCTCATGGATGCAGTGTGGTTCTCTTCGGTCACACTCACGTTCCTCTGGCAGAAAGGTGCGAAGGGGTGCTGCTTTTGAATCCGGGATCGGTTTCTCTTCCAAAATCTGAGGCCGGTCCGACTTTTGGTATCATCGATATGGATGAGAAAAAATTTTACCTCTGCTCGCTGGAAGGTGATGTTTTGAAAGAGGTGATGCTCGTTGAACGAGAGTGAGAGAAAGATCGTGGAGGAGTTTCAGAAAGAAACTGGAATCAACTTCAAGAACGAAGAACTTCTCTTTCGGGCTCTGTGCCACAGTTCTTACGCGAACGAGCAAAATCAAGCGGGAAGAAAGGACGTGGAATCGAACGAAAAGCTGGAGTTTCTGGGGGACGCCGTTCTAGAACTCTTCGTGTGCGAAATACTTTACAAAAAGTATCCGGAAGCGGAAGTGGGAGACCTGGCCCGGGTGAAATCCGCAGCGGCGAGCGAAGAAGTTCTCGCCATGGTTTCCAGGAAGATGAATCTTGGCAAATTCTTGTTTCTTGGAAAGGGAGAGGAAAAAACTGGTGGACGTGATAGAGATTCCATACTCGCCGACGCGTTCGAAGCGCTTCTGGCTGCCATATACCTCGATCAGGGCTATGAGAAGATAAAGGAGCTATTTGAGCAGGAATTCGAGTTCTACATAGAAAAAATCATGAAGGGTGAAATGCTCTTCGACTACAAAACGGCTCTCCAGGAAATAGTTCAGAGCGAACACAAAGTGCCACCAGAATATATACTGGTGAGAACAGAAAAAAACGATGGTGACAGGATTTTTGTTGTGGAAGTGAGGGTGAATGGGAAGACCATCGCCACAGGCAAGGGTAGAACAAAGAAAGAAGCGGAAAAGGAGGCCGCAAGAATCGCCTACGAAAAGCTTTTGAAGGAGAGATCATGA

Protein sequences of DBSCAN-SWA_2

>NC_021214|1110716:1119435|1116473_1117067_+|WP_004080341.1|DBSCAN-SWA
MFITFEGIDGSGKSTQIQLLAQYLEKRGKKVILKREPGGTETGEKIRKILLEEEVTPKAELFLFLASRNLLVTEIKQYLSEGYAVLLDRYTDSSVAYQGFGRNLGKEIVEELNDFATDGLIPDLTFYIDVDVETALKRKGELNRFEKREFLERVREGYLVLAREHPERIVVLDGKRSIEEIHRDVVREVKRRWKLDV
>NC_021214|1110716:1119435|1117059_1118160_+|WP_004080339.1|DBSCAN-SWA
MFRIAIVELKRILKKRSSLMMIIAAPVLVVLISLLFMQGYNLQTMKLGIYNEDNSIWSSLVMRFIGTILRQENIVKVDQNYEKLLKEGKLNAVIVIPKGFAAKLYSKQPTQMIFIPSPIDLHLAAAIYNVLDSVLADFQGSAFFDPKVLRYIFTESDYPVPRLKLKDSELRFSDLISPFVVFFTAILITVSLASVSTFLDREKNLHEMFLVYNLPAWKYACGKILAYTIIGASVSFIAYSLTVILTGDSLDFFITSVLILLNALLHTSVGFLVSSISPDKSLANILGVSVIGISLFSSGFAIPISNLPDIFRRIAMSTPVFRTMYALRVYQLEHTVDNRSIFVVLLWTVVLFSISILSGKFVIRRG
>NC_021214|1110716:1119435|1114948_1115890_+|WP_004080343.1|DBSCAN-SWA
MSVNLKGRSLLTLLDFSPEEIRYLLDISKQVKMENRSKLRTERFKGMTLAMIFEKRSTRTRLAFETAFAEEGGHPIFLSPNDIHLGAKESLEDTARVLGRMVDAIMFRGYKQETVEKLAEYSGVPVYNGLTDEFHPTQALADLMTIEENFGRLKGVKVVFMGDTRNNVATSLMIACAKMGMNFVACGPEELKPRSDVFKRCQEIVKETDGSVSFTSNLEEALAGADVVYTDVWASMGEEDKEKERMALLKPYQVNERVMEMTGKSETIFMHCLPAVKGQEVTYEVIEGKQSRVWDEAENRKHTIKAVMIATLL
>NC_021214|1110716:1119435|1113751_1114945_+|WP_004080356.1|DBSCAN-SWA
MNRVVVGLQWGDEGKGKVVTYLSRYHDIVARFSGGANAGHTVNYGDFKVIHHLLPSADFTKNRGIAIGSGVLLDPQVLTEELRELKEKFPDYSGEIFISESAHVVLPVHKEMDRIIDEVLKIGTTKRGIGPACADRVMRVNVRVAELGNEEKLRYFLEKNLSLKKIYGVDFDAEKMMGDLSTFYETIKDFVVSPVQLKRILEEKSVLFEGTQGVLLDLDVGTYPYVTSMNCSSSGVSAGMGFPVEVDEVLGVFKAYTTRVGEGPFPTELTGEEGEKLRKAGHEYGSTTGRPRRCGWLDLPLLRYAIEISGVDSLVMTKADVLNGFEKIKVCVRYSDGRDLVSLRDLEKKEPVYEVFDGWKSLEDKNFERFVDFIERETGRPVRYISTGEKLEDIVEV
>NC_021214|1110716:1119435|1110716_1112036_+|WP_004080361.1|DBSCAN-SWA
MLEQVRIQKMVNGGYGLAHLSNGKVVLVEGAYPGEEVLIKTYREKRDFSFGKVVSLLKESEDRIKPPCRYFGRCGGCHWMDVKYETQLRYKKEVLIDLFERSNLKVEVEDVEPSDLVFHYRTKMEFHFQGRKLGLKKRNSDFVIDIKDCEVAPEGTGEILNTVKEAVQVLNVPVYNWETRKGVLKHLVIRYAFSTDQFMVIFVTKTESFPWGRDLVRAVLKRFPKIHSIIHVMNSKDSVVLRGPYKTLYGEGVIVEEFDWERFQIPPTAFFQSNYSITSKLIDHVYREQALQGNEVVLDLYAGIGTFSVRTSFSAARVISVESSRVAVKAGKANANINSRKNIEYVEQDVLDFLKNYSGRADRIILDPPRSGAGPEVMKEIARLSPERIVYVSCDPSTLVRDLKVLVENGYSIVRVKPFDMFPQTYHVETAVTLVKGDR
>NC_021214|1110716:1119435|1118162_1118726_+|WP_004080337.1|DBSCAN-SWA
MRILVISDTHGSLSCTEKALKSAGNFDEIWHLGDVLYHGPRNPLPEGYSPKELASLLKKHRVKYIRGNCDADVDIRVLEIPEMPRIGMEFLGDVKILLVHGDQFEYEGGDPVSLAQAHGCSVVLFGHTHVPLAERCEGVLLLNPGSVSLPKSEAGPTFGIIDMDEKKFYLCSLEGDVLKEVMLVERE
>NC_021214|1110716:1119435|1112450_1113746_+|WP_004080360.1|DBSCAN-SWA
MVERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRKGQRGSSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEKE
>NC_021214|1110716:1119435|1118712_1119435_+|WP_004080335.1|DBSCAN-SWA
MNESERKIVEEFQKETGINFKNEELLFRALCHSSYANEQNQAGRKDVESNEKLEFLGDAVLELFVCEILYKKYPEAEVGDLARVKSAAASEEVLAMVSRKMNLGKFLFLGKGEEKTGGRDRDSILADAFEALLAAIYLDQGYEKIKELFEQEFEFYIEKIMKGEMLFDYKTALQEIVQSEHKVPPEYILVRTEKNDGDRIFVVEVRVNGKTIATGKGRTKKEAEKEAARIAYEKLLKERS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004080361.1|1110716_1112036_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	4.3e-49	27.5
WP_004080360.1|1112450_1113746_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.0e-18	28.5
WP_004080356.1|1113751_1114945_+	adenylosuccinate synthase	L7Y4J5	Megavirus	1.1e-51	33.5
WP_004080343.1|1114948_1115890_+	ornithine carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	2.4e-22	31.2
WP_004080341.1|1116473_1117067_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.3e-34	43.3
WP_004080339.1|1117059_1118160_+	ABC transporter permease	NA	NA	NA	NA
WP_004080337.1|1118162_1118726_+	phosphodiesterase	NA	NA	NA	NA
WP_004080335.1|1118712_1119435_+	ribonuclease III	A0A167RGU4	Powai_lake_megavirus	8.1e-18	27.3

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_021214|1270505:1288426|DBSCAN-SWA
GATGAAGTTGAGATATCTGAACATTCTCAAGGAGAAGCTTGGAAGAGAACCCACCTTCGTCGAGCTTCAGGCTTTTTCAGTCATGTGGAGCGAACACTGTGGATACTCCCACACGAAGAAATACATAAGAAGATTACCGAAAACGGGTTTTGAGGGAAACGCGGGTGTGGTGAACCTGGATGATTACTATTCCGTTGCTTTCAAGATAGAGAGCCACAATCACCCGAGTGCGATAGAACCTTACAACGGTGCAGCAACGGGTGTCGGTGGAATCATCAGAGACGTCCTCGCGATGGGAGCCCGCCCAACGGCCATATTCGATTCACTCCACATGTCCCGAATCATAGACGGTATCATAGAGGGAATAGCCGATTACGGTAATTCCATAGGCGTTCCAACGGTCGGTGGAGAACTCAGGATCTCCTCACTATACGCGCACAACCCCCTCGTGAACGTGCTCGCAGCGGGTGTTGTGAGAAACGACATGCTGGTCGATTCGAAAGCATCGAGACCGGGACAGGTCATAGTGATCTTCGGAGGAGCCACAGGAAGGGACGGAATCCACGGGGCGTCTTTCGCTTCGGAGGATCTCACGGGTGATAAGGCAACCAAGCTTTCAATTCAGGTTGGTGACCCGTTCGCTGAAAAGATGCTCATAGAAGCGTTCCTGGAGATGGTGGAAGAGGGACTCGTGGAAGGAGCTCAGGATCTGGGAGCGGGCGGTGTGCTGTCCGCAACTTCGGAACTCGTAGCGAAGGGGAATCTCGGAGCGATCGTTCATCTGGACCGTGTTCCCCTGAGAGAACCGGATATGGAGCCCTGGGAAATCCTCATAAGCGAAAGCCAAGAAAGAATGGCGGTCGTCACATCACCTCAGAAGGCGAGCCGCATTCTGGAAATAGCCAGGAAGCACCTTCTTTTCGGCGATGTCGTTGCCGAAGTGATAGAAGAACCAGTTTACAGGGTGATGTACAGAAACGATCTCGTCATGGAAGTTCCCGTCCAGCTCCTCGCAAACGCCCCAGAAGAGGACATAGTCGAATACACACCCGGAAAGATCCCAGAGTTCAAAAGGGTGGAATTCGAAGAGGTGAACGCGAGGGAAGTCTTCGAGCAGTACGATCACATGGTCGGAACGGATACCGTGGTTCCACCCGGATTCGGCGCGGCCGTGATGAGAATAAAGAGAGACGGGGGGTACTCCCTCGTCACACACAGCAGGGCGGATCTGGCTCTTCAGGATACCTACTGGGGAACCCTCATAGCCGTGCTCGAGAGTGTGAGAAAGACGCTCAGCGTTGGTGCGGAACCCCTCGCTATAACGAACTGCGTGAACTACGGGGATCCCGATGTTGATCCGGTGGGACTTTCGGCCATGATGACCGCTCTCAAGAACGCTTGCGAATTCTCCGGTGTTCCCGTTGCATCGGGAAACGCTTCTCTCTACAACACGTACCAGGGAAAACCCATTCCACCCACCCTGGTTGTGGGAATGTTGGGGAAGGTGAACCCGCAGAAAGTGGCAAAACCGAAGCCTTCGAAGGTGTTCGCGGTGGGATGGAACGACTTCGAACTCGAAAGGGAAAAAGAACTCTGGAGAGCCATAAGAAAACTCTCAGAAGAAGGTGCTTTCATCCTCTCTTCGTCACAGCTTCTGACGAGAACTCACGTGGAGACTTTCAGAGAGTACGGCTTGAAGATCGAAGTGAAACTGCCAGAAGTGAGGCCGGCGCATCAGATGGTGCTCGTCTTCTCTGAGAGAACTCCCGTAGTCGATGTTCCTGTGAAGGAGATCGGAACGCTCTCGAGGTGATGATATGTGCGGAATCGCAGGAGTCTGGAATGTGAAAGATGCCTTTTCTGTCCTTCACGACGTGCTTCTCGGTCTTCAGCATAGAGGACAGGAAAGTGTGGGTGTTGTGGTAGACGGGTTCAAAACGATAAAAGGAAAAGGACTCGTAGACACCGTTCTCACCGAAGACAGGTGGGAAGACGCTGAAAAGGGTATTGGACACGTAAGGTACTCCACGGCAGGATCGCTCGAGGACATTCAGCCAATCGTGGCGTTCACGAGAAAGGGAAGGCTCGCGATCGCTCACAACGGAAACATACCCAACGGCGAAAAGTGGATAGAGATGCTCAAAGAAAAAGGAGCGGTTTTCCAGAGCTCGCTCGACTCGGAGGTCTTCCTTCATCTCATCTCGATGTCTGAAGGTGACCTGAAAGAGTCCATAGTGAAAGCGCTGAAGAAAGTCCCTCTTGCCTACTCACTTCTCATTCTACACGAAGAATTCCTCGCTGCGGCGAGAGACCCATACGGCGTCCGTCCCCTGTTCTATGGAAAATACGGTGATGGAATCGTTGTGGCATCGGAAGACGCAGCGCTGAAAGCGATAGGTGTGGAAGACATAGAAGAAGTTCCCTCTGGAACGGTCGTGTTCTTCTCGAACAAAGGCACAGAAACGGTGAGGTTCTCCAAAAAAGAAAAGCGGTTCTGCTCCTTCGAATTCATCTATTTCGCGAGGCCGGACAGTCACTTTCTCGATCAGAGTGTACACATAGCCCGTTACAGAATGGGTGAAGAACTCTACAGAGAAAACCCGATAGAAGCGGACGTGGTCGTTCCGGTGCTGGACTCCGGACTTTCCGGAGCGATGGGATTTTCTTCGGCTTCGGGTATACCTCTCGACATCGGTCTCATGAGGAACAGATATGTGGGAAGAAGTTTCATCATGCCGGTGGACAGGGAAAAGATCGTCAAGAAAAAACTCGTCCCCATAGAAGACGTTGTGAGTGGAAAGAGGGTTGTTGTAATCGATGATTCGATCGTCAGAGGAACAACCATGGGCATCATCGTGAAGATATTGAGAGAGGCGGGTGCGAAGGAAGTACACGTTGGCATACACTCTCCACCTGTACGTTTTCCCTGTTTCTACGGAATAGATACCGCCAGAAAGAAAGAGCTCGTCGCGGGAGAACGTGCCGTGGAAGAAGTGAAAAAAATAGTCAACGCAGACTCTCTCTTTTACCTTTCACTCGAAGGGTTGAAAAGAGCCATCGGGAGGAGTGAACTGTGTGTAGCGTGCTTCAGCGGAGAGTACCTCCACGAATAGTCGTTCTCGCTTCGGGAAACGGAAGCAATTTCGAAGCGATCGTGAACGCAGCGCGAAGCGGTGAATTGAGTGCGGAAATCCAGATGCTCCTTGTGGACAGAAACTGCTACGCAATAGAGCGAGCGAAAAAACTGCAGATCCCCTGGGAAAGGCTCGAGAAACCCTGGGCAGAGTCTCTGAAAAAAAGACTCGAAGAGTTGAATCCCGACCTCGTGGTCCTCGCCGGTTTCATGAGGATTCTTCCGGCGGAGATCGTCGAAAGGTGGAAGTGGAAGATCGTCAACATCCACCCTTCGCTTCTTCCCGCGTTCCCCGGGACCCACGCCATCGAGAAGGCCTACGAATACGGTGTGAAGGTCACAGGAATCACCATCCACTTCGTTGATGAGGGAGTCGACACCGGTCCCATCATCTTTCAGAAAGCAGTTGAAATAAAGAAAGACTGGTCTCTCGAAAGACTGGAAGAAGAGATCCATAAGATAGAACATCGGTATTATCCGCTCGTCATTCAAAAGGTACTGGAAGGAAAATGGAAGATCGAAGGAAGGAGGGTTATCCTTGAAGAGGATATTGGTTAGTCTCTACGAGAAAGAAAAATATCTGGATATTCTGAGAGAACTCCACGAAAAAGGCTGGGAGATCTGGGCGAGCTCCGGCACCGCCAAGTTTTTGAAATCAAACGGAATAGAAGCAAACGACGTGAGCACCATAACGGGTTTCGAGAATCTCCTCGGAGGGCTCGTGAAGACCCTCCACCCGGAGATATTCGCCGGCATCCTCGGACCGGAACCCAGATGGGATGTGGTCTTTGTGGACCTATATCCACCCCCAGACATCGACATAGGAGGAGTCGCTCTTCTTCGAGCAGCTGCCAAAAACTGGAAAAAGGTGAAACCCGCTTTCGACATGGAAACACTCAAACTCGCGATTGAGATAGACGACGAAGAGACGAGAAAGTACCTCGCTGGAATGACCTTTGCGTTCACCAGTGTGTACGATTCGATAAGGGCCAACCAGTTTGTCGAGGGTATTTCTCTCGCCTTCAAGAGGGAAGATCTTCAGCTGAGGTACGGAGAGAACCCTCACGAAAAAGCGTTTGTGTATGGAAAACCAGCTTTTGAGATTCTGCACGAAGGAAAGACAATCTCATTCAACAACATCTTAGACGCGGAAAACGCGTGGTTCATGGCGAAGAACCTGCCGAGGATGGGTGCGGTTGTGGTGAAACACCAATCTCCCTGTGGTGCTGCGATAGGAGAAGACAAAGTGGAAATCGTGAAGAAGGCCATCGAGGCGGACGACGAATCCAGTTTTGGAGGGATCCTGGCCGTGAACTTCGAAATGGACGAAGAAGTTGCGAAGTCATTGAAAAAGTACCTCGAGGTGATCGTGGCACCTTCCTTCACACAGGAAGCGATCGAGGTTCTCTCTAAGAAAAAAGTGCGTCTCTTGAAGCCTGGGGATTACGCTTCGTGGGCTGGAAAGATGGCATTCGGTTCTCTCGTCCTGAGTGAAAGAAAGTACCCCGAAGGGAATTTTGAACTGGTAGTTGGAGAGCCTCTCTCGGAAAAAGAGCTTGAGGATCTGGAATTCGCTTACCGTGTTGTGGAAGGAGCGAAATCCAACGCTGTTCTCATAGCAAAAGACGGTGTAACTGTGGGAATAGGGAGCGGGCAGCCTTCGAGAAAGAGAGCTGCCTGGATCGCCACCGTGATGGCAGGAGAAAAAGCGAAGGGAGCGGTTGCGGCTTCCGATGCGTTCTTCCCGTTCCCGGACTCGCTCGAAATACTCGCTCAGGCTGGTGTGAAAGCGGTGGTCGCTCCTCTCGGATCCATAAGAGACGAAGAAGTGATCGAAAAAGCCAGAGAACTTGGAATCACGTTCTACAAAGCTCCGAGCAGGGTTTTCAGGCACTGAGGGGTGAAAGCGGTGAGGGTACACATACTCGGTTCTGGAGGAAGGGAACACGCGATAGGATGGGCTTTCGCAAAGCAGGGGTACGAAGTCCACTTCTATCCGGGAAACGCCGGAACGAAGAGAGATGGAACGAACCATCCCTATGAAGGGGAAAAAACCTTGAAAGCCATTCCCGAAGAAGACATCGTGATACCGGGATCCGAGGAATTCCTGGTAGAAGGGGTCTCGAACTGGAGATCCAACGTCTTTGGCCCGGTGAAAGAGGTCGCAAGGCTCGAAGGATCCAAGGTCTATGCCAAAAGGTTCATGAAGAAGTACGGTATAAGAACCGCTCGTTTCGAAGTGGCAGAAACTCCAGAGGAATTGAGAGAGAAGATAAAAAAATTCTCTCCTCCTTACGTGATAAAGGCGGACGGGCTCGCTCGAGGAAAGGGTGTTCTGATCCTCGACTCTAAGGAAGAAACCATCGAAAAGGGATCGAAACTCATCATCGGAGAGCTCATAAAAGGTGTGAAAGGCCCTGTTGTGATAGATGAATTTCTCGCCGGGAACGAGCTTTCCGCCATGGCGGTTGTGAATGGAAGAAATTTCGTGATCCTTCCCTTCGTCAGAGATTACAAGAGACTGATGGACGGTGACAGGGGACCGAACACGGGAGGTATGGGCTCCTGGGGGCCTGTAGAAATCCCTTCCGATACGATCAAAAAGATCGAAGAGCTCTTCGATAAGACTCTGTGGGGAGTGGAGAAAGAAGGCTACGCGTACCGGGGGTTCCTCTACTTGGGTCTCATGCTCCACGATGGTGATCCCTACATACTCGAGTACAATGTGAGACTGGGCGATCCAGAAACAGAAGTGATAGTGACGTTGAATCCCGAAGGATTTGTCAACGCGGTTCTCGAGGGATACCGCGGTGGTAAAATGGAGCCGGTGGAACCGCGTGGATTCGCCGTGGACGTGGTTCTCGCAGCGAGGGGCTATCCCGACGCTCCCGAAAAGGGCAAAGAGATCACCCTTCCCGAAGAAGGTCTCATATTCTTCGCGGGAGTCGCGGAGAAAGATGGAAAACTCGTAACCAATGGCGGTCGTGTTCTTCACTGTATGGGAACAGGAGAAACGAAAGAAGAGGCACGAAGAAAGGCTTACGAACTCGCGGAAAAGGTCCACTTCGAAGGTAAGACCTACAGGAGGGATATCGCTCTATGAAATACACTTACAGAGAAGCAGGAGTCGATGTCGAGAGGGGAGAAAGCTTCGCAAAAACTATAAAAAGCGCTGTAAAACTTCCTGAATGGGTGATGAAAGAGCCCACGGGATACGCTTCCATACTCACGATCACAACTCCCCCCGTTGTTGTAACGGCCGATGGGATCGGCACCAAACTCATCCTTCACAGAAAGCACGGGACCTGGCGCTACGCGGCTGAGGACCTTGTGGGTATGAACTACAACGATCTGGTCTGCGTGGGAGCGAGGCCTGTGGCCTTTCTGGACTACCTTGGGGTCGAGAGAATCTCCGAAGAACACGAGTCGTTCATAAAAGAGCTCGTAAACGTCCTTGACAGCGTGGATGTGAAACTGGTGGGCGGTGAGACCGCTGAGATGCCCGATGTGTATCGTGGAGACTGGGACGCTGTGGGGTTCGCTGTCGGCGTTTTAGAAAAACGGATACCGGTTGATAAGATAAAAGAAGGGGATGTGATCGTTGGTATTCCGTCATCGGGATTCCACTCGAACGGCTGGTCCCTCATAAGAAGGATCATAAAGGAGGAATCCATAAAGATCGAAGAACTTCCCTTTGAACTCCTGAAAGGAACACGCATATACAGAGAAGTCATCGAGTTGTTCGATCTGGTGAAAGGGATCGCACACGTGACCGGCGGGGGAGTGGTGAGGGCGCTGAAGAGAGTCCTCGGAAAGCTTGGGGCGCACGTTTCTCTACCAAAGAGGGACTTCGTTGATTGGATATTGAAATATGTAGACTTCAACGAAGCGGTCAACACCTTCAACATGGGTGTTGGAATGTTTCTGATCGTGGAAAAACAAAAGGTGGACGAGGTTCTGGCCAGAGTGGATGGAACAGTCGTTGGGAAGGTATCCTCAGACTGGAGAATCGAGTACGGAGGTGAGGGGGGATAAGTGTGATCGAGAGTTTCGTTAAAGGATTCAGGGAGATAGTTCAAAATACAAAACTCGCTGTGATAAGCGTTATGGCTCTCGTTCTGGGGTTTGTGACGGAAGTGCTTTACATCTTTGCCGGAAAGTACGATTTTCTGAGCTTCGATTTCTTCGTCATAAAACTCTTTGAAGAGGTACTGCTCGCATTGTTGATGGGACTACTTCTGGTTCCAAGAAGAAGAGAAAATCTTCTCAGTCTTCTCGTGTTTTCAGCGTTTTACGGGTTGACGGTAAGTGCTGGTTTTTCTCTGTTCGTCCTTCCCGGTTTTGTGGCCTTCATGTTTCTCTTCTTTGTCCCCCTGCTCTCCGCTAAAGACGAATCTCCTTCCAGCGTCCTGGAAAAGAACTACAGAATGGTGTTCAAAGGGGAAAAGACGGTGGACGTTTTCCTCGCTGCAGCCGTTGTGTTCATCGTCTGGTTCATACCGTACCTGGGTTCCATAATATCGAATCTCTTGAGAGTCGTTCTGGTCTACTCGATGTACCGGATAATGGAGGGATCCTATGAAAAGACTGAGAGTGACACTGGCTCAGCTTAATCCGACCCTTGGAGACTTCGAGGGAAATCTGAAGAAGGCAATAGAAGCCCTCAGAGTGGCGGAAGACCGGGGAAGTGATCTCCTTGTCTTCCCGGAGCTCTTTCTTCCCGGTTATCCTCCTGAAGACCTCATGCTCAGGCTCTCATTCCTCAGAGAGAACAGAAAATACCTCCAGAAGTTCGCTCAGCATACAAGAAATCTCGGTGTTACCGTCTTGATGGGCTTCATAGACAGCGACGAGGATGCGTACAACGCCGCCGCGGTTGTGAAAGACGGTGAGATCCTTGGAGTGTACAGGAAGATATCTCTGCCGAACTACGGGGTTTTCGATGAGAGAAGATACTTCAAACCCGGAGAGGAACTCCTCGTCGTGAAAATAGGCAACATCAAAGTGGGAGTTACCATCTGCGAAGACATTTGGAATCCAGTGGAACCGAGCGCCTCGCTTTCCTTGGGTGAGGGAGTTCATCTCATAGCGAATCTTTCGGCTTCTCCCTACCACGTGGGGAAACCTGTTCTGAGAAAGGACTATCTTTCCATGAAGGCTTACGACTATCACGTGGCCATGGCCTACTGCAACATGGTCGGGGGTCAGGACGAACTCGTCTTCGATGGAGGAAGCATGGTGGTTGACGCTTCAGGAGAGGTCATAAACTACGGAAAGCTCTTCGAAGAGGAGATCATCACGGTGGATCTGGATCTGGACGAGAACCTCAGAGTCTCGCTGGTAGATCCTAGAAGAAGGTACATGAAGACTCAGAACTATCCGGTGAAAACCGTGGAAGCGGGAAATCTCCGGGAGAAATCCGGGCATTTTGAACCGGTGGTGAATCCTCTTCCTGTGAGAGAAGAAGAGATGTTCAGGGCTCTGATCACGGGTCTGAGAGACTACGTGAGGAAAAACGGTTTTGAAAAGGTCGTGATAGGGCTCAGTGGGGGAATGGACTCTTCCCTCGTCGCGGTCATAGCAACAGAAGCCCTGGGAAAAGAGAACGTGAAAGGTGTCCTCATGCCGTCCATGTACACCTCAAAAGAAAGTATCGAAGACGCGCAAACACTGGCAAAAAATCTGGGCATAGAGACTTTCATCATTCCCATCACGGATGTGTTTCACTCCTACCTCGAAACACTCAAAGGCGTTTTCGCTGGGCGAGAACCAGATATAACCGAAGAGAATCTTCAGGCGAGGATCAGAGGAAACTACCTCATGGCACTTTCCAACAAGTTCGGATGGCTCGTTCTCACAACGGGAAACAAAAGCGAGATGGCAACGGGATACGCGACTCTCTACGGAGACATGGCGGGAGGATTCGCCGTTATAAAGGATGTTTACAAGACAGACGTTTACAGAATAGGAAGATGGTACAACAGCTGGAGAGGAAAAGAGATCATTCCGGAAAACATCTTCGTGAAACCCCCAACGGCGGAGCTCAGGCCGGGCCAGACGGACCAGGAGAAACTACCACCGTACGAGGTGCTCGATGAAATACTGAGACTCTACATAGAAGAAGGGCTCGATCCAGAAGAAATCGCATCAAAAGGCTTCGACAGGAAGACCGTGCTCGACGTGACGGAAATGATACGAAAGAACGAATACAAGAGAAAACAGGCCGCTATCGGCGTGAAGATCTCCACGAGAGCTTTTGGGAAAGACTGGAGAATGCCGATCACGAACAGATTTAAAGAACCTCTTTGAGAACGTTCAGGATTTCCTCGGGTTTCACCAGAGCAACCGCACCCGCTTCAAGAAGCGCTTTACCGTCGTTCAAAGAGTGAACGACTCCATAGATTCTTTCTATGCCGGCGCTTTTTGCGGCTTCAACACCGCTCTTTGAGTCTTCGAAGACCACAACCTTCTCTGGGACCACATTCAACCTTTCCAGAACGAGAAGGTATATCTCTGGATCAGGCTTTCCGTTCTTCACCTGATCACCGAACACCATGACGTCGAAGTACTTTTCGAGATCGAGTCTTCTCAATCTCTCCAGCGCTTCTCGCTGTGGTGTGGAGGTTGCGAGCGCGAGTTTTATTCTTTTGCTCTTTACGAACTCGAGCGCCTCTCTTACACCCGGATTTTCCTTGAGAAGCTCAGAGAAAACGCGCTTTTTTTCTTCGTGGACCCTCTTTTTGAAGTTCTCCAGAGAATCTTTTATCTCCAGAGCTTCCATGAGGATGGGAAGACCTTCTCTTTCAGGAACTCCCATTATTCTCCTGTGGAGATCCTCCGTGTAAGGTTTTCCATAGCTTTCCGCGACTCTTCTGTAAGCTTCGAAGTAGAGAGGCTCTGTGTCCATGAGCACTCCATCCATGTCGAAAATCACCGCTTCCATTCCTTACTCCTCCTTTCTTTTAAAAGAATAACATGAGAAGTTTAACCTGTCTAAATCGGATCTTTGTGGTAGTATTAAATATGAAACCACGACCAGGGGGGTTTCTAAATGGTATCCAGGAGAATATCAGAGATTCCCATATCGAAAACCATGGAACTCGACGCGAAGGCCAAAGCCCTCATAAAAAAGGGAGAAGACGTGATCAATCTAACGGCTGGTGAGCCGGATTTTCCCACACCGGAACCCGTCGTGGAAGAAGCGGTGAGATTTCTCCAGAAAGGAGAAGTGAAATACACAGATCCTCGTGGTATCTACGAACTCAGAGAGGGTATAGCGAAAAGGATAGGCGAGAGATACAAAAAAGATATCTCACCGGATCAGGTCGTGGTGACGAATGGAGCGAAACAGGCTCTGTTCAATGCTTTCATGGCCCTTCTCGATCCCGGTGACGAAGTGATCGTGTTTTCTCCCGTCTGGGTCAGCTACATTCCTCAGATCATCCTTGCTGGTGGCACGGTGAACGTGGTTGAGACGTTCATGAGTAAAAATTTCCAGCCCAGTCTGGAAGAGGTGGAAGGGCTTCTTGTTGGGAAAACGAAAGCCGTTCTTATCAACTCGCCGAACAATCCCACTGGTGTGGTGTACAGAAGAGAGTTCCTTGAAGGACTTGTGAGACTTGCCAAGAAGAGGAATTTCTACATAATCAGCGACGAAGTCTACGATTCCCTTGTTTACACGGATGAATTCACATCGATACTCGATGTTTCTGAAGGATTCGACCGGATAGTTTACATAAACGGCTTCTCGAAGTCTCACTCCATGACCGGCTGGAGGGTGGGTTACCTGATATCGAGCGAAAAAGTAGCGACCGCTGTGTCGAAGATCCAGTCTCACACCACCTCCTGTATCAACACGGTAGCACAGTACGCCGCCTTGAAGGCTCTGGAAGTGGACAACTCTTACATGGTTCAGACCTTTAAAGAAAGAAAAAATTTCGTGGTGGAAAGATTGAAAAAGATGGGTGTTAAGTTCGTGGAACCAGAAGGTGCGTTCTACCTCTTTTTCAAAGTCCGGGGTGACGATGTGAAATTCTGTGAAAGGCTCCTCGAAGAAAAGAAGGTTGCACTCGTTCCAGGATCCGCTTTTCTGAAGCCTGGATTTGTGAGGCTTTCTTTTGCCACATCTATAGAAAGACTTACGGAGGCGCTGGATAGAATTGAAGACTTCCTCAATTCTCGTTGATTTCCTGAAGAGAAACTGGCACAAATACCTTCTCGGTGTTCTTTCACTCATCGCGGTGGACCTCCTTCAAGTCTACATTCCACGTGTCATCGGAAAGATCGTTGACATGCTGAACACAGAAACGATGAACTTCGATACACTCAAAATAATGTTGTTTTGGGTGATGGCCGCCGCGAGCGGGATGTTTATTGGAAGGTTCTTCTGGAGATTCTTCCTTGGTGGCACTGCAAGAAAGTTTTTCCTCGAGACATCGAACAAGATGTTCTCAAAGCTGCTCAGTCTCACTCCCGGTTTCTTCGATCGAATGAAAAGCGGTGAACTCATGGCAAGGTTCACCAACGATCTGAGCCTTCTGAGAAGAGTGCTCGGCCAGGGTGCGATACTCTTCTTCGATTCTTTCATCATGATCGTGATGGTCTTTTTCTTCATGATAGGTAACGTGGGTTGGAAGCTCTCCTGGATCAGCTTTGCGCCGCTTTTGCTTCTTGCCCCTGTTTCGATGAGCTTTGGACGACTCATACACAGAAAAGTATCGGAAGTTCAGAGATCCTTCTCGGAACTTTCCGGGTTCACCGAAGAAACGATTTCGAGTGTGCGCATTGTGAAGAGCTTCTCGGTGGAAGACGTCTCATTCAAGATATTTGAAAACAGGGCACTCAAAAACTACGAAGACACTCTCAGTGCAATCAAAGTCTCCAGCGTTTTCAGGCCCCTCATCAATCTTATCGCTTCGACCGCTTTTTTCCTCGCCCTTCTCTACGGTGGAAGAGCCGTTATAAACGGGAAGATCTCTCTCGGTGATTTCATAGCCTTCAATTCCTACCTTGGAATGCTCGTCTGGCCGATGATGGCCTACGGTTTCATGGTGGATCTGTTCCAGAGGGGAAGAGCGGCTATGAGACGTCTGGACACGATCTTCACCGCTCAACCCGAAGTTAAAGAACCCGAGAAGCCGATCAGGATAGATCACTTTGAAAGTTTTGAAGTGAGAAACCTGACCTACAGATACCCCGGAACAGAACGTGAAGTTCTGAAAAACGTCACCATGAAGATAAACAGGGGAGAAATGATAGGCATCGCCGGCAGTGTTGGAAGTGGAAAGTCCACGATAGCAAAGCTTCTCGTGAAGCTCTATCCGGTGGAAAGGGGAAAGATATTCATAAACGGTGTGGACATAAACGACGTTTCTTCGGAGAATATCAGATCCATCGTCACTCTGGTTCCGCAGGAAACGTTTCTGTTCTCAGACACGGTGAGAAACAACATAACGGTCGGTTTGGAAAACGTCGATGAGAAAAAGATCGAAGAAGTGACAAAACTTGCGGCCGTCTACGACGATATCATGAGCTTTCCAGAAAAATTCGACACGATCGTTGGGGAAAGAGGTGTGACGCTTTCGGGCGGTCAGAAACAGAGAATCACCATAGCCCGCGCTCTCATAAGAGATTTCGAAGTTTACATATTCGACGACTGTCTCTCGGCCGTTGACCCTGAAACCGAAGAGAGGATCATAGATTCGATCAGAAAAGGAATGAAAGGAAAAACGATCGTCGTCATAACACATCGATTGAAGGTGTTGAAAAACGCCGACAGGATATATGTCTTGCACGAGGGAAGAGTGATAGAAGAGGGCACTCACGAGGAATTGATGATCAGGGATGGCATGTACAGTAGAATGTACAGAAAACAGCTCATCGAGGAGGGATAGGTAAATGAGCGGAAGAAAGATAGGGGTTGTCACCGGTATATTCCAGTCCAGTCCGTACGAATTCTTCGTTCGAATGACCGCCGAAAAGCCAGGAGAAGCGTACAAGGTATTCGCTCAGATAGAGGATGTTGTGAAGGTTGAGTACCTCACGGGGTACGGCACCGTCGTCACGTACGGAATGATCGTTGATATACAGAACAGATGGGATGGAGATCTGAGAAACGGCTACGAAGAGGAAGTTGCACTCGAGAAGTTGAAACCTGCCTATCCGATATACATCGCGAAGGTGAAGGTGACAAGATCGTTTCTGAAAGAAGGAAACAAGCTCCTCGAAGACGCTCCGGAGATCCCTCCAAACATAGGCTCCCCCGTCTTTCTCGTCGGAGATGAGGAGATAGACATCGCCCTTGGATTCGATGAGTTGAAGAGAAAGAACGTTGCACTGCCGGTTGGTCTGCTGAAGAACGGAAGGCCGGCTTATCTCGATTTGAGATACATCCTGGGAGACAACGGAGCCCACATAAACGTCTCCGGACAGTCCGGTGTTGCGGCGAAAACGTCTTACACCACGTTCCTCGTCAAGTCGATGATAGAAACGTCCAGCAAAAACGATGGAGATCTGATGAGAGAGCTGAGAGAGGCGAGATACATCATCTTCAACGTGAAGGGAGAGAGTCTGCTGTTTCTCGATCGCATTTCGAAGGAGTGGTATTCAGAAAGGGAGAAATGGGATGAAATGTACAGGGTTCTCGGCATTGAACCAAAACCTTTTGAAAATGTCGCATTCTACGCTCCCAGCAGGGAGAAGGGAGCTTACATACCGGATGTCAACAAGAGATTGATCGGTGTGAACGTTTACGGCTGGGACGTGTTCGACATCGTCGAAATGAACCTTCTGGAACTCATGTTCGATCCAGATGAGATGACGAGAAACCAGAACTTTCAGCTCGCGGTCTGGTCCCTCCAGGAGCACCTTTCCCAGAGAATGGAAGAGATGTACCAGGAATTTCTGAAAGAGGGATACATCGTTGACAGAAAAAAACTGCCGTCAGAAGCACTGCGCGAAGTGGTGATGAAGAAAGGTGAAGTCGTGGATCTTCCACTTGATCTCGATAGTTTGATAAAAGATCTTGGAGAAGGTGGAAGGACAAGAGAGTATCTCCTGGGAGAACACGTCCAGAAGCAGACGATCGGGATGCTGATCAGGAGATTGAAAGCCGCTCAAAAGATGGACTTCGACAGACTCTGGGTGAAACCGCCTCTGAAAGTGGAACCGTGGCAGACCAACTATCGGATCGACTGGAACGTGCCGGGAAGGGTCACAGTCATCGACATTTCGAAGTTGAGAGAACGCGCACAGGCGTTCGTTGTAGGTGCGATTCTTTCCGAGGTAATGAGAGAAAAAGAAAGAAACAGCGGTTTCACCCAGCCCGTTTTCATTTTCCTGGACGAGCTGAACAAGTACGCACCAAGACACGGCGGAGGAGCCCTTGCGAACATCTTCAGAGATGTGGCGGAAAGAGGAAGATCTTTCAGAGTGATCCTCATTGGAGCCGAACAGACCGCTTCCGAAGTGGATTACAGGGTAATCACGCAAGCCGCTACGGTGGTTGTGGGCAGGCAGAAAGGAGCCGAACTCATAAAACCCGAATACTCGCATCTCACAGAGCACTACAAGAGAAAAGCAGCACTCTTGAGACAGGGAGAAGTGATCATAGATCAGCCGTTCTTGAACCTTCCTCTCACGGTGAAGTTTCCACTCCCAGCCTGGTGCACGAGAGAAGGCGGGTGGCACAACCCGGAGGGGAAAACGTGGGAAGAAGAGGAGTTCATCATTTGAAGTGAACGATGAACTCTGATCCAACGAGCCACTGAGAGTTCACTTCCAGCCTGTAACCTATCGTGTCGCACAGGTGTTTCACTATGGAAAGTCCCAGGCCAGAACCGGGCGCCATCTTGAGTGCTTCTGAACCTCTGTAGAAGCGCTCGAATATCCTGCTCTTCTCCTCTTCTTTGATACCGATTCCCTGATCTTTCACACTCAGTCTTTCACCGGTGATAGAAATCTCCACCACAGAATCGGGATAAGAGTACTTCACGGCGTTTGAAACGAGGTTCTTCAAGATCGTGTGGAACACGAACCTGTCAGTTTCGATTGTTTCAACATCCACAAAAACGTTTACCTTGATCTTCTTTGACTCGATCTTTTCTCGAAGCTCTTCCAAGACCATGTGAACGACTTCTTCGACAGGAATGTGCTCCATCTTGAGTTCGTAAAGTCTCAGCTGTATCATGGTGAGCACCTTGAGCTGTCTGATGATCGTTTCCATTCTGTCCAAGGAGCGCTCAACTTTTCCGAGTATTTCGAGTTTTTCTGGATCGTTTTCTATGTCCTTCAGAAGAAAAACGTTTGCCTTTGACGCAGAAAGAGGTGTGAACAGCTCGTGGGAGACGGCCGTTACAAAATCGAGTTTTGCCTCGCTGAGAGTTCTCTCCTCGGTGAGATCGTTCACAAAGAGAAGACTCTTCTTCGGAAGGTAGCGGAGGGAGACGAACCTTTTCGAGTGGAGTTCAAAAAAATAGGCGTTTGTTTCAAGGGAGAAATTCTTTCTTTCTTGAACATCTCTGATGAATCTATCCATTTCCTTGCACGTGAAGATCGACATCAGATTCTTTCCCTTTTTGAAGCCGAGTTTCTCACCCGGTTTGTTCGCACCTTCCACTTCCAGGCCCTTCAGTATCACGATCGCTTCTCTGATATGATCGAGATCTTCAAGCTCTATCACCCTCATCACCCCGTGTTGAAAACTTGTATCCCAATCCCCTCACCGTTTTTATCCATCCCTTTCCTATCTTCGATCGAATGGCGCTGATGTGGACATCCACTACCCTGTCAGAGACGTAATCGTCTCCCCACACCCTGTTCAGGATCTCCTCTCTTGAAAAGACCTTGTTCGGGGTCGTGGCGAGGAGTTTCAAAAGCTCGAACTCTTTGGCTGTCATCTCAACGTTTTTTCCATCGTATCTGACTATGTAATCCTCTGGAAAGATCTCGAGTCTTCCAAATCTCAGTACCTTCTGTTCTTTCCCCATCCTTCTCAGAACCGCTTTCACACGTGCGAGAACTTCCCTTGGATTGAAAGGTTTTGTCACGTAATCATCCGCTCCGAGCTCTATTCCAAAGATGCGGTCCATGTCCCTGTCCCTTGCCGAGATGATGATGATGGCCATTTCCGGGTGAGAAACTTTCATCTCGGGAATTTCGTCCATCGCCACACCGTCGGGAAACATGAGATCGAGGAGAAGCACGTTGTACGTTCCTTCAGAGAGTTTTTTCTTGAGATCGAAAAGGGACTCTGCTTCGTCGCACTCGTATCCTTCGGTTTCCAGGTATCTCTTCAACACGCTCCTTATGTCTTCGTCGTCTTCAGCTATCAGCACCTTCACTCCCACTCTCAACACCCCTCAGGAATTCCTTCATGTTTTTTCCCGTTTCTATGTATATGACCTCCTCACAGAGGTTGTTGGCGTGATCTCCCACCCTCTCAAGGTCTCTTGCGATGAGTATGTAAACCAGCGCCAGCTCGGCCGAGATGTTTCCCTCCCTTATTCTTTCCACCACGATTCTTCTGATCTTCTTTTCCATCTCGTCTATCACGTCGTCGAACTTCCAGAGCCTGAAAGCCAGATCCACATCTTCTTCAACGAAGGCCTTGAAAGCGTCCTGAACCACCTTCAGGGTGCTTCCGAACATGTCTTTGAGTTCCTTGAGCATTTCGAATTTGATCTTCTCTTCAGAGAGAAAGAGACACTTCTCAGCTATGTTGCAGGAGAGATCTCCTATCCTCTCCAGATCGTTTGAAAATTTCAAGATGGTGATGATGTACCTGAGCTGTTTCAGGATGGGGTTGTACCTCGCTATGATCTGGTAAGCTTTTTCTTCTATCTCCCTGTTCAGTTCGTCTATCATATCGTCCGACTCGAGGACCTTCCTGGCGAGCGTCTCATTCATCGTCTCGAGGCTCTCTATCGCGTCGTTCAAAGATTCAGAGACCAGAAAGAGCATCTTCGAGACATCAGACTTGAGAAGTGTGAGTTCCCTTTCGAAGTGAACGTGATCGACCATACTTTCCGCCTCCATCATCCGATTTTTCCTGTCAGGTACTCCTCGGTGAGCCTGTTCTTCGGTCTCTCCACGATCTCCCTCGTTGGTCCGTATTCGATGAGTTCTCCTCTGTACATGAACGCTATGTAGTCCGCTATTCTTATCGCCTGGCCGATGTTGTGTGTGACGATCACGATGGTGTAATTCTCAGAGAGTTCTTCCAGAAGCTTTTCTATCCTCTGAGTCGCTATGGGATCGAGGGCCGATGTCGGCTCATCGAGAAGAATCACCTCGGGTTCAACGGCGAGTGCTCTCGCTATGCAGAGCCTCTGCTGCTGACCGCCGGAGAGTCTCGTACCAGATTTGTTCAGTTCTGACTTCACCTCGTCCCATAGGGCTGCCTTTTTCAATGATTCCTCTACTATCCGGTCGAGAATGTGTTTGCTCTTCACCCCGTGTATCCTGGGGCCGAACGCGACGTTGTCGTAGATCGACATGGGAAAAGGTGTCGGTTTCTGGAAGACCATACCGACTCTCTTTCTGTACTCCGTCACGTCGAGCTGTGGATCGTAGATGTCCTGTCCCTTGAAGTATATCTTCCCTTCAACCCTGAATCCAGGCAGATGATCGTTCATCCTGTTGATGCTCCTCAGGAGAGTTGTTTTACCGCATCCGGAGGGACCTATTATGGCGGTTATCTGGTTTTTGAAGATCTTCATCGTCACGTTCTTGACGGCTATCTTCTCGCCGTAGTAAGCGCTGAAGTTTTCGATCTCAATGATGGGCTCCAT

Protein sequences of DBSCAN-SWA_3

>NC_021214|1270505:1288426|1286302_1286983_-|WP_004080003.1|DBSCAN-SWA
MGVKVLIAEDDEDIRSVLKRYLETEGYECDEAESLFDLKKKLSEGTYNVLLLDLMFPDGVAMDEIPEMKVSHPEMAIIIISARDRDMDRIFGIELGADDYVTKPFNPREVLARVKAVLRRMGKEQKVLRFGRLEIFPEDYIVRYDGKNVEMTAKEFELLKLLATTPNKVFSREEILNRVWGDDYVSDRVVDVHISAIRSKIGKGWIKTVRGLGYKFSTRGDEGDRA
>NC_021214|1270505:1288426|1274175_1275534_+|WP_004080014.1|DBSCAN-SWA
MKRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGLVKTLHPEIFAGILGPEPRWDVVFVDLYPPPDIDIGGVALLRAAAKNWKKVKPAFDMETLKLAIEIDDEETRKYLAGMTFAFTSVYDSIRANQFVEGISLAFKREDLQLRYGENPHEKAFVYGKPAFEILHEGKTISFNNILDAENAWFMAKNLPRMGAVVVKHQSPCGAAIGEDKVEIVKKAIEADDESSFGGILAVNFEMDEEVAKSLKKYLEVIVAPSFTQEAIEVLSKKKVRLLKPGDYASWAGKMAFGSLVLSERKYPEGNFELVVGEPLSEKELEDLEFAYRVVEGAKSNAVLIAKDGVTVGIGSGQPSRKRAAWIATVMAGEKAKGAVAASDAFFPFPDSLEILAQAGVKAVVAPLGSIRDEEVIEKARELGITFYKAPSRVFRH
>NC_021214|1270505:1288426|1286957_1287656_-|WP_004080001.1|DBSCAN-SWA
MVDHVHFERELTLLKSDVSKMLFLVSESLNDAIESLETMNETLARKVLESDDMIDELNREIEEKAYQIIARYNPILKQLRYIITILKFSNDLERIGDLSCNIAEKCLFLSEEKIKFEMLKELKDMFGSTLKVVQDAFKAFVEEDVDLAFRLWKFDDVIDEMEKKIRRIVVERIREGNISAELALVYILIARDLERVGDHANNLCEEVIYIETGKNMKEFLRGVESGSEGADS
>NC_021214|1270505:1288426|1273577_1274195_+|WP_004080015.1|DBSCAN-SWA
MCSVLQRRVPPRIVVLASGNGSNFEAIVNAARSGELSAEIQMLLVDRNCYAIERAKKLQIPWERLEKPWAESLKKRLEELNPDLVVLAGFMRILPAEIVERWKWKIVNIHPSLLPAFPGTHAIEKAYEYGVKVTGITIHFVDEGVDTGPIIFQKAVEIKKDWSLERLEEEIHKIEHRYYPLVIQKVLEGKWKIEGRRVILEEDIG
>NC_021214|1270505:1288426|1272321_1273617_+|WP_004080018.1|DBSCAN-SWA
MCGIAGVWNVKDAFSVLHDVLLGLQHRGQESVGVVVDGFKTIKGKGLVDTVLTEDRWEDAEKGIGHVRYSTAGSLEDIQPIVAFTRKGRLAIAHNGNIPNGEKWIEMLKEKGAVFQSSLDSEVFLHLISMSEGDLKESIVKALKKVPLAYSLLILHEEFLAAARDPYGVRPLFYGKYGDGIVVASEDAALKAIGVEDIEEVPSGTVVFFSNKGTETVRFSKKEKRFCSFEFIYFARPDSHFLDQSVHIARYRMGEELYRENPIEADVVVPVLDSGLSGAMGFSSASGIPLDIGLMRNRYVGRSFIMPVDREKIVKKKLVPIEDVVSGKRVVVIDDSIVRGTTMGIIVKILREAGAKEVHVGIHSPPVRFPCFYGIDTARKKELVAGERAVEEVKKIVNADSLFYLSLEGLKRAIGRSELCVACFSGEYLHE
>NC_021214|1270505:1288426|1285362_1286322_-|WP_004080004.1|DBSCAN-SWA
MRVIELEDLDHIREAIVILKGLEVEGANKPGEKLGFKKGKNLMSIFTCKEMDRFIRDVQERKNFSLETNAYFFELHSKRFVSLRYLPKKSLLFVNDLTEERTLSEAKLDFVTAVSHELFTPLSASKANVFLLKDIENDPEKLEILGKVERSLDRMETIIRQLKVLTMIQLRLYELKMEHIPVEEVVHMVLEELREKIESKKIKVNVFVDVETIETDRFVFHTILKNLVSNAVKYSYPDSVVEISITGERLSVKDQGIGIKEEEKSRIFERFYRGSEALKMAPGSGLGLSIVKHLCDTIGYRLEVNSQWLVGSEFIVHFK
>NC_021214|1270505:1288426|1270505_1272317_+|WP_004080021.1|DBSCAN-SWA
MKLRYLNILKEKLGREPTFVELQAFSVMWSEHCGYSHTKKYIRRLPKTGFEGNAGVVNLDDYYSVAFKIESHNHPSAIEPYNGAATGVGGIIRDVLAMGARPTAIFDSLHMSRIIDGIIEGIADYGNSIGVPTVGGELRISSLYAHNPLVNVLAAGVVRNDMLVDSKASRPGQVIVIFGGATGRDGIHGASFASEDLTGDKATKLSIQVGDPFAEKMLIEAFLEMVEEGLVEGAQDLGAGGVLSATSELVAKGNLGAIVHLDRVPLREPDMEPWEILISESQERMAVVTSPQKASRILEIARKHLLFGDVVAEVIEEPVYRVMYRNDLVMEVPVQLLANAPEEDIVEYTPGKIPEFKRVEFEEVNAREVFEQYDHMVGTDTVVPPGFGAAVMRIKRDGGYSLVTHSRADLALQDTYWGTLIAVLESVRKTLSVGAEPLAITNCVNYGDPDVDPVGLSAMMTALKNACEFSGVPVASGNASLYNTYQGKPIPPTLVVGMLGKVNPQKVAKPKPSKVFAVGWNDFELEREKELWRAIRKLSEEGAFILSSSQLLTRTHVETFREYGLKIEVKLPEVRPAHQMVLVFSERTPVVDVPVKEIGTLSR
>NC_021214|1270505:1288426|1281796_1283530_+|WP_004080006.1|DBSCAN-SWA
MKTSSILVDFLKRNWHKYLLGVLSLIAVDLLQVYIPRVIGKIVDMLNTETMNFDTLKIMLFWVMAAASGMFIGRFFWRFFLGGTARKFFLETSNKMFSKLLSLTPGFFDRMKSGELMARFTNDLSLLRRVLGQGAILFFDSFIMIVMVFFFMIGNVGWKLSWISFAPLLLLAPVSMSFGRLIHRKVSEVQRSFSELSGFTEETISSVRIVKSFSVEDVSFKIFENRALKNYEDTLSAIKVSSVFRPLINLIASTAFFLALLYGGRAVINGKISLGDFIAFNSYLGMLVWPMMAYGFMVDLFQRGRAAMRRLDTIFTAQPEVKEPEKPIRIDHFESFEVRNLTYRYPGTEREVLKNVTMKINRGEMIGIAGSVGSGKSTIAKLLVKLYPVERGKIFINGVDINDVSSENIRSIVTLVPQETFLFSDTVRNNITVGLENVDEKKIEEVTKLAAVYDDIMSFPEKFDTIVGERGVTLSGGQKQRITIARALIRDFEVYIFDDCLSAVDPETEERIIDSIRKGMKGKTIVVITHRLKVLKNADRIYVLHEGRVIEEGTHEELMIRDGMYSRMYRKQLIEEG
>NC_021214|1270505:1288426|1277674_1278250_+|WP_004080011.1|DBSCAN-SWA
MIESFVKGFREIVQNTKLAVISVMALVLGFVTEVLYIFAGKYDFLSFDFFVIKLFEEVLLALLMGLLLVPRRRENLLSLLVFSAFYGLTVSAGFSLFVLPGFVAFMFLFFVPLLSAKDESPSSVLEKNYRMVFKGEKTVDVFLAAAVVFIVWFIPYLGSIISNLLRVVLVYSMYRIMEGSYEKTESDTGSA
>NC_021214|1270505:1288426|1279929_1280580_-|WP_004080009.1|DBSCAN-SWA
MEAVIFDMDGVLMDTEPLYFEAYRRVAESYGKPYTEDLHRRIMGVPEREGLPILMEALEIKDSLENFKKRVHEEKKRVFSELLKENPGVREALEFVKSKRIKLALATSTPQREALERLRRLDLEKYFDVMVFGDQVKNGKPDPEIYLLVLERLNVVPEKVVVFEDSKSGVEAAKSAGIERIYGVVHSLNDGKALLEAGAVALVKPEEILNVLKEVL
>NC_021214|1270505:1288426|1283534_1285370_+|WP_004080005.1|DBSCAN-SWA
MSGRKIGVVTGIFQSSPYEFFVRMTAEKPGEAYKVFAQIEDVVKVEYLTGYGTVVTYGMIVDIQNRWDGDLRNGYEEEVALEKLKPAYPIYIAKVKVTRSFLKEGNKLLEDAPEIPPNIGSPVFLVGDEEIDIALGFDELKRKNVALPVGLLKNGRPAYLDLRYILGDNGAHINVSGQSGVAAKTSYTTFLVKSMIETSSKNDGDLMRELREARYIIFNVKGESLLFLDRISKEWYSEREKWDEMYRVLGIEPKPFENVAFYAPSREKGAYIPDVNKRLIGVNVYGWDVFDIVEMNLLELMFDPDEMTRNQNFQLAVWSLQEHLSQRMEEMYQEFLKEGYIVDRKKLPSEALREVVMKKGEVVDLPLDLDSLIKDLGEGGRTREYLLGEHVQKQTIGMLIRRLKAAQKMDFDRLWVKPPLKVEPWQTNYRIDWNVPGRVTVIDISKLRERAQAFVVGAILSEVMREKERNSGFTQPVFIFLDELNKYAPRHGGGALANIFRDVAERGRSFRVILIGAEQTASEVDYRVITQAATVVVGRQKGAELIKPEYSHLTEHYKRKAALLRQGEVIIDQPFLNLPLTVKFPLPAWCTREGGWHNPEGKTWEEEEFII
>NC_021214|1270505:1288426|1280688_1281822_+|WP_004080007.1|DBSCAN-SWA
MVSRRISEIPISKTMELDAKAKALIKKGEDVINLTAGEPDFPTPEPVVEEAVRFLQKGEVKYTDPRGIYELREGIAKRIGERYKKDISPDQVVVTNGAKQALFNAFMALLDPGDEVIVFSPVWVSYIPQIILAGGTVNVVETFMSKNFQPSLEEVEGLLVGKTKAVLINSPNNPTGVVYRREFLEGLVRLAKKRNFYIISDEVYDSLVYTDEFTSILDVSEGFDRIVYINGFSKSHSMTGWRVGYLISSEKVATAVSKIQSHTTSCINTVAQYAALKALEVDNSYMVQTFKERKNFVVERLKKMGVKFVEPEGAFYLFFKVRGDDVKFCERLLEEKKVALVPGSAFLKPGFVRLSFATSIERLTEALDRIEDFLNSR
>NC_021214|1270505:1288426|1276736_1277672_+|WP_004080012.1|DBSCAN-SWA
MKYTYREAGVDVERGESFAKTIKSAVKLPEWVMKEPTGYASILTITTPPVVVTADGIGTKLILHRKHGTWRYAAEDLVGMNYNDLVCVGARPVAFLDYLGVERISEEHESFIKELVNVLDSVDVKLVGGETAEMPDVYRGDWDAVGFAVGVLEKRIPVDKIKEGDVIVGIPSSGFHSNGWSLIRRIIKEESIKIEELPFELLKGTRIYREVIELFDLVKGIAHVTGGGVVRALKRVLGKLGAHVSLPKRDFVDWILKYVDFNEAVNTFNMGVGMFLIVEKQKVDEVLARVDGTVVGKVSSDWRIEYGGEGG
>NC_021214|1270505:1288426|1278215_1279946_+|WP_004080010.1|DBSCAN-SWA
MKRLRVTLAQLNPTLGDFEGNLKKAIEALRVAEDRGSDLLVFPELFLPGYPPEDLMLRLSFLRENRKYLQKFAQHTRNLGVTVLMGFIDSDEDAYNAAAVVKDGEILGVYRKISLPNYGVFDERRYFKPGEELLVVKIGNIKVGVTICEDIWNPVEPSASLSLGEGVHLIANLSASPYHVGKPVLRKDYLSMKAYDYHVAMAYCNMVGGQDELVFDGGSMVVDASGEVINYGKLFEEEIITVDLDLDENLRVSLVDPRRRYMKTQNYPVKTVEAGNLREKSGHFEPVVNPLPVREEEMFRALITGLRDYVRKNGFEKVVIGLSGGMDSSLVAVIATEALGKENVKGVLMPSMYTSKESIEDAQTLAKNLGIETFIIPITDVFHSYLETLKGVFAGREPDITEENLQARIRGNYLMALSNKFGWLVLTTGNKSEMATGYATLYGDMAGGFAVIKDVYKTDVYRIGRWYNSWRGKEIIPENIFVKPPTAELRPGQTDQEKLPPYEVLDEILRLYIEEGLDPEEIASKGFDRKTVLDVTEMIRKNEYKRKQAAIGVKISTRAFGKDWRMPITNRFKEPL
>NC_021214|1270505:1288426|1287670_1288426_-|WP_004079999.1|DBSCAN-SWA
MEPIIEIENFSAYYGEKIAVKNVTMKIFKNQITAIIGPSGCGKTTLLRSINRMNDHLPGFRVEGKIYFKGQDIYDPQLDVTEYRKRVGMVFQKPTPFPMSIYDNVAFGPRIHGVKSKHILDRIVEESLKKAALWDEVKSELNKSGTRLSGGQQQRLCIARALAVEPEVILLDEPTSALDPIATQRIEKLLEELSENYTIVIVTHNIGQAIRIADYIAFMYRGELIEYGPTREIVERPKNRLTEEYLTGKIG
>NC_021214|1270505:1288426|1275546_1276740_+|WP_004080013.1|DBSCAN-SWA
MRVHILGSGGREHAIGWAFAKQGYEVHFYPGNAGTKRDGTNHPYEGEKTLKAIPEEDIVIPGSEEFLVEGVSNWRSNVFGPVKEVARLEGSKVYAKRFMKKYGIRTARFEVAETPEELREKIKKFSPPYVIKADGLARGKGVLILDSKEETIEKGSKLIIGELIKGVKGPVVIDEFLAGNELSAMAVVNGRNFVILPFVRDYKRLMDGDRGPNTGGMGSWGPVEIPSDTIKKIEELFDKTLWGVEKEGYAYRGFLYLGLMLHDGDPYILEYNVRLGDPETEVIVTLNPEGFVNAVLEGYRGGKMEPVEPRGFAVDVVLAARGYPDAPEKGKEITLPEEGLIFFAGVAEKDGKLVTNGGRVLHCMGTGETKEEARRKAYELAEKVHFEGKTYRRDIAL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004080021.1|1270505_1272317_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.2e-79	34.1
WP_004080018.1|1272321_1273617_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	9.6e-46	32.5
WP_004080015.1|1273577_1274195_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.5e-25	39.0
WP_004080014.1|1274175_1275534_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH	Q58MG4	Prochlorococcus_phage	1.2e-41	39.1
WP_004080013.1|1275546_1276740_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_004080012.1|1276736_1277672_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3HQK7	Synechococcus_phage	1.4e-38	35.5
WP_004080011.1|1277674_1278250_+	hypothetical protein	NA	NA	NA	NA
WP_004080010.1|1278215_1279946_+	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	1.1e-92	36.6
WP_004080009.1|1279929_1280580_-	HAD family phosphatase	A0A1D8KNV9	Synechococcus_phage	3.3e-10	26.1
WP_004080007.1|1280688_1281822_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_004080006.1|1281796_1283530_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.6e-41	26.9
WP_004080005.1|1283534_1285370_+	ATP-binding protein	A0A139ZPI2	Marinitoga_camini_virus	4.3e-31	28.2
WP_004080004.1|1285362_1286322_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.6e-16	28.7
WP_004080003.1|1286302_1286983_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.8e-28	32.6
WP_004080001.1|1286957_1287656_-	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_004079999.1|1287670_1288426_-	phosphate ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.5e-17	28.4

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NC_021214|1643407:1651020|DBSCAN-SWA
TTCACCTTCTTTTCGGCAGGAGCACCCTCATCAGCGTTCCCTGGTTGATCTCACTCTCAACCTCTATCTTTCCTCCGTGTTTGTCAACGATCGTTTTCACTATCGTGAGACCCAATCCCGTTCCGCCCATCTTTCTGGAACGCGCTTTATCCACCCTGTAGAACTTCTCGAAGATTCTGCTCTGGGCTTCCTTGGGTATTCCAGGTCCCGTGTCTTCTACCTCAACAACCACCCAGTCCGGTGTATCGTAGGCCCTCACCCAGACCTTCTTTTCTCCTTTTTCCTTCAAAGATGTGTATTTGACAGCGTTGTCCACAAGATTCAGGAGCATCTGGATCAGCCTTTCTTTGTTTCCCCTGACCACAACATCCTCACATTCAACGATGAGATCCACTTCGTTCTCCTCGGCTATCGGTTGTATGATTCTGTAAACGTATTCTATCACTTCACACAGATCCACATCTTTCATTTCAAAATTGGCTTCGCTTTCTTCTATTTTCTCAAGATCGAGAAGATCGTTGATGAGGCGTGTCATTCGAGCGGATTCTTCCTCTATGATCTTCAAAAACCTTTTAACCAGTTCCTTGTTCTCCAGATCATCTTCGAGGAGCGTTTCCGCATAACCGTGGATGGAGGTGAGGGGAGTTCTGAGTTCGTGTGAAACTGTGGCTATGAATTCTCTTCTCATCTCGTCGAGCTTTCTTTCCTTGGTCACGTCATGGAAGAGAATGACAAAGATTTTGTCGCCGCTTTTCAGCTCGACGGGTATCACCTTCACGTGGAAGTATTTCTTCTCGTTACCAACATAGGTAACGAGAGTTCCTTCCTGCGGTTCTTCGCTTTTGATTGTTTCTTCCACCATCTCGTTTATATAGTAATCTTCGAATATTTCATAATAAGGTCTTCCTTCGGGGTTGATTCTGCCTTGCACGAGTTCACGGGCAATTTCGTTCAAAAATGTGATCTTTCCCTCTCGATCCAGAATGAATATGGGTTCGCTGAGGCTGTTCAAAATCGTGAGAAAGTTATCTCTGCTCACTTCGACACGTGAAATTGTTTCTTTCAGATTGTCCACGTACTTTTTCAGTCTCTCGAAAAGATAAAGTGGGGGAACACCCTTTTCCCCCAGCATATCTGACAGCTTTTCGATGAGAATTTTGTACTCGGAGAGACGCTTCTTGAACACCAGAAAGAGCAGGACGAATAGAACGGCTACTATGACGAACAGGAACACACTCATAGATCAGTCTTCCTTTCCGGGGTCTCTGAATTTGTATCCCTTTCCTCTCACAGTGATTATGTATTTCGGATTCGAAGGATCTTCTTCTATCTTCGTTCTCAGCCTTCTTATGTGAACATCTACAGTTCTCGTATCTCCGTAGTAATCGTATCCCCAGAGTTTGTCCAGAAGAACATCCCTGCTGAAAACTTTTCCTTCGTTTTCCGCGAGGAATCGGAGCAGTTCAAATTCGAGAGGAGTGAGGTTCACTTTTTTCCCTCTCACTTTCACTTCGTACTTTTCCACATCGATTTCAAGATCCTTGGCTATGATCTTCTTAGGCCTTTCTTCCTTGCTCTGAGTAGCGGTGGAAAGCCTTCTGAATATAGCCTTCACCCTCGCAAGAAGCTCTCTCACGCTGAACGGCTTGGTGATGTAGTCGTCCGCACCGAGCTCCAGCCCAAGCACCTTGTCGAATTCTTCTCCCTTTGCGCTCAGGAAGATCACGGGGGTGTTCTTGTATTTCTCCATGGATCTGATCTTCCTGACCAGCTCGAAGCCGTCGATTCCAGGAAGCATGATATCCACTATGAACATGTCCACGTCTTCGTCGTTGGCAATTTTGAGTGCTTCCTCTCCATCATAAGCCTTGAGCACCTCGTATCCTTCCTTGGAAAGGTTATATCCTACCAGCTCAAGAATTGCCGGGTCGTCGTCAACCACCAGAATCTTCTTTTTCGCCATCTTCGATCCCCCGAGGGGGTACACCTCCTTTCAGATCTGGTTTCTATACTATTTTAACATTTACGAACTAGTTTTTTGATAGGATCTTTTCCTGAAAGTGAACCATGCAGAAAGAAACAGAAAGAGCAGAAAAAGAGACACGTAGAAGAAGATCATCATCTTGTTCGCAAAGAGAGATTCCGGTTTAAACTCCACACCAAAGAGTCCGGAAAGGTAGAACAAAACCAGCACTGAAAAAATCGCAGCACCCACCACAACTGAGAGGATTCTCGCAAATTCTTTTTCCTTGCGGTAAGCAGTCAATCCAGCTAAAAGTCCAATGAAAACGGAAAGTCCAAACGTTATCCAGTTCATGTACTGAACACTTTGAAGGTTAAAAGAACTCACCAGAAAGTTTATAACGTAGTAAGCGACGAAGGTCACGGTGACGAGAGCAGCGAGGAACACCAGGTATCTGTACAGAACGTAAAGCACAACTGCGGTTAAAACACCTGTTGCCACCAGTACAACAACCTTCACATTCTCATTCGTGAGATAGGATTTGAGAAATTCGATATTCGAAAGAAGAGGAAACACGAAGTTGATACCGATTACAAAACCGATCACCGCAAAAGCTATGTGTTCAACATACCTGGCAGCGAACATGAGAAAAAGAGCGGCGGGTAGAGAAAAATACCAGTTTTTAATAATCAACCTGAAGAAATCCCCTATCAACCCCTCCACGCACAATCCCTCCCTTTAAAATCAGAAATGCCCCGCAAGGGGGCCAGCTTTCAAAAACAGCAAGAAATTCACTCCTGAGTTGTTTCGAGAGTTCTCAGGTATTCGTTCACCTTCTCGAAAAGTCTCGCTTTTCTTCTCGCACCCTGATTCTTGTGGATGACTCCCTTGGAAACGGCTTTGTCTATGGCAGCCTGCGCTTTCCTGGTGAGTTCAAGAACGACTTCTTTCGGTTCTTTGTTCTCGATAGCTTTGAGAACCTCTTTTATTCTGTTCTTGAAGAAAGTCTTGTAAGCCTTGTTTCTGAGTCTTCTCTTTTCAGAAACTCTGACCCTTTTCTTTGCAGATTTGATATTCGGCACTACTTGATCCCTCCCTTACATATTGAAAGCTCTTTTCAACTCATCTACCATGTCGAGTTTCTCCCATGTGAATTCCTCTTCGTTCCTTCCAAAGTGACCGTAGGCGGCTGTTTTCCTGTAAATAGGTCTCAAAAGATTCAGTTTCTTTATGATCGCACCCGGTCTGAAATCGAACAGTTCAGTGATCACCTTGAGAAGTTTGTCTTCATCCACCTTCGCGGTTCCATACGTGTCGATCATTATGGAAACGGGTTTCGCGACACCTATAGCGTAAGAAAGCTGTATGAGGAACTTGTCCGCAAGACCTGCAGCCACAACGTTCTTCGCTACATATCTTGCCATATAGTGAGCCGATCTGTCAACCTTTGTGGGATCTTTTCCGCTGAACGCCCCTCCGCCGTGGGGTACCCAACCACCGTAAGTGTCAACGATGATCTTTCTCCCTGTGAGCCCCGTGTCGGCCATGGGACCTCCAAGAACAAATCTTCCCGTTGGATTCACCAGTATCTTCATTTTGTCGTCCCTGTACTGTTCTGGAATCACAGGATTTATGACGTGTTCTATTATCGCCTCTCTCAGATCTGCCTGGGAGATATCCGGATCGTGCTGAGTTGAAATAAGCACTGTGTCGACACGGACTGGTTTGTCGTCCTCGTATTCTATGGTCACCTGTGTCTTTCCATCTGGCCTGAGGAAAGGAAGAGTCCCGTTCTTTCTGACCTCAGCGAGTCTCATGGCGAGTTTGTGGGCGAGAGTTATGGGAAGGGGCATGTACTCAGGGGTTTCGTTGGTGGCGTAGCCGAACATGATTCCCTGGTCGCCAGCTCCGAGCGCCTCGAACTCGTCAGCCACTTCCTCTCCTGTTTTGACCTCGAGCGCCTTGTCTACACCGAGAGCTATGTCAGGAGACTGACTGTGGATGCTGGTGAGCACTCCGCAGGTTTCCCCATCGAATCCGTACTTCGCCCTCGTGTATCCTATCTCCAGAATGGTCTTTCTCGCTATATCGGGGATCTCAACATAAGCTCTGGTGGTAACCTCTCCCGCGATGATGACAAGCCCTGTTGTTACGAGTGTTTCAACGGCAACCCTGCTCCTTGGATCCTGCTCGAGCATGGCGTCGAGTATGGCGTCGGAAATCTGGTCGGCGATTTTGTCCGGATGCCCTTCTGTTACGCTCTCGCTGGTGAAAAGTCTTCTCATCTCCCATCCTCCTTTCGCTGATCTTATAACAGCCTTGATAGTTTATCACAATCTTTCTTAAAAAAAGGTTACATCATTGTTTTTGCGATTCTTCAAATTCTTCTCGGGTTATAAAAGTTCCACCCTCCAGAGAAACAGACACCGGTTTATAAGAAGACGTGAAGGTCGCAACAAGATGTATCTTGTTGGGACATTTTGAACCCACATAGAGCTTGTCTATCTTGTAAGGAACGCCCGGGTTATCGTAATCCACGATGAAATCGTACCCCGTTCTCAGATGACTTCTGAAGACTTCCCCACACCTGTCACATTTTATGTAAACTACAAGGGATCCCTTTTCCCTGTAAAACGGGTTTTTGTTCAGGTCTTTCTTTTTCTTTCCAAAAAACAGAAAGAGCATGATTTCACCTCCGCTGCAGGTAGAAAGAAAATTCCTTCTTCATGCCCCAGATATCTTCAATAACGACTGTGTATTTGGCAAAATCTGGGGCTTTTCCCAATTCGGGAAATTTGTTCACCTTTATCATCGAAGAAAACGTTTCGGGGAACAATTTGTACCAGAGCTCAAACCTGTACGCGGCCGAAACGGACTTCCTATCGTACACTCCCCAGACGTTTGTGAACTCGGACCAGGGAATCTGATCGAAAGAGATCTGATAGATCTCTTCACCTTCCAAAAGGAGTGAGATCTTCTTGAGTCCTAACGTGTTGTTGAACCCTTTCGAATAGGCTTTGATCGCAAGATCCGGGAAATTTCCACTGAACGGGTACGTCCTCCCCTCGACGAAATCGTACACACTGTCTCCTATCTTTATTTTTTCCAGAACAATATCCTCATCCACGGGTTTTGGAAGGTTCAAGAAAGTCGAAGGGTCGTAGGAAACTTCCTCGTTCCTGTCTCTTATCTCGAAGTGTGCGTGGGGAATGGGTGCCTCTCCTGTGGTTCCTGAGTATCCGACGACTTCACCTTTTTCGAACCAGATCTCTTTCTCAGGGAAGTTCACGACGATCCTCACATTCCCGAACTCTTGTTTCAAAGAACTCGCTACCGTTTCCAGTTTTTTCGAGAATCTGCTCAGATGGGCGTAGAGCGTTCTGTATCCATTCTCGTGTTCCAGAACCACTGTGTAGCCGTATATATCGTCCTCGTCTATTTCGATTCTGACGAGCCAGCCTCTCTCGGAGGCGTATATGGGAACTCCTTCTTTCAATCCCGTAGAAAAGTCGATTCCCATGTGAAAATGAGGTCCTCTGTTTCCACTCCCTCTGTACTCACCGAAAGTTGCCGAAACCCTTGGAGAATCAACGGGTGCGGAGAACGAAAACACAACCGCGGAGAACACCATCAAGGAAATCAAAAGCAACCACCTTTTCACGTCTCTTCCCTCCTCATCTCTTAACGGTTCTTGCTATGTCCATGAGTTTCTTTCTGAGCAAAAGGCGCTTTGCTGGACTGATTCGATCGATGATCAAAACTCCGTTCAGATGATCGAACTCGTGCTGAAAAACCCTTGCAGCGTAACCTTCCAGTTCTTCTTCCACGTATTCTCCCCTTGTGTTCTGGTATTTGACCTTTATTCTTTTGCTCCTTTCTATCTCGACGAAGATCTCGGGAAAGCTGAGGCACCCCTCTTCTGCTACTTCAGTTTCTGGATCGATTTCAAGAATCTCCGGATTTATCACGGCAACCGGACCATTTCCAACGTCCATGACGAAGAACCTCTGAGATATTCCAACCTGCGGTGCCGCGAGTCCCACACCGTCGTAGTGATACATCGTCTCTATCATTCTTTCTATGGTCTTTTTCAGGTTCTCGTCGAACTTTGTAACGGGTTTTGCCCTCTTTCTCAAGACGGGATCTCCAAAGACTCTTATTCTGTACATCAGTCGTACACCTCCCTTAACTTCTTCAGACACTGTTCGTTCGTGAGAAAGGGATGTATCGGAGTGATGGAGACGTACCCTTCTCTAACCGCCTTGTAGTCAACATCGTCTCTATCGTCGTCTTCGATGACCTCTCCCATCATCCAGTAGTACTTCTCCCCAAAGGGTGAGACTCTCTCTTCGAAGTAATCGTTCCACCTTCTTCTGCTCTGCCTTGTGAATCTCCATCCCTTTATCTCACCAGCAGGCACGTTTATGTTCAGCATGGTGAAAGGATCGAGGAGTGAGAAGTCGAATTCTTTCAGAAAGTCGATCAAAAAACGTGCCGCTCCTTCGAAATCGGGACTCTCGTAGTTAGCACTCGATATGGCAATCGAAGGAATGTTCATCATGGCACCTTCCATCGCACCCGAGACCGTCCCAGAGTGGAGAATATCCATGCCCATGTTGGGCCCCCTGTTCACACCACTCACGATGAGATCGACCCTTTTATCCATGACCACGTTGTAGGCGAGTTTCACACAGTCCGCGGGCGTTCCTGTAGTGGAGTACGCAACCACCCTCTCTGAGATGAAAACCTTCTTCATCCAGAGCGGAACGTGTATGGTGATGCTGTGACCAGTTGCGCTCCTCTCTTTATCGGGAGCCACCACGAACACCTCGTGTTCCTCGGAAAGAAGCTCTGCGAGGACGATGATCCCCTTAGACTGTATCCCGTCGTCGTTGGTTACCAGAATTCTCATACCGATCCTCCCACAGGTTTATCTTCCCACATTTCTTCCAGAGTTTCCACTTGAAAGGAATCTCCACATCGTCGAACTCTCTCTCCACGAATTCCTCCCAGCTTCCACAGAAATCGATTGTACCATTCGAGATGTGGAGTATGAAGTCCATATCATCCAGATACTCCAGCTCGTGTGTTACCAGTATTATTCCCTTTCCTTCATTCTTGAGGCTCTCGAGCACCTGAAATATCTCCCTCTGAGAGGGAGGGTCCAGCATGGAAACCGGTTCATCTAAAGCGAGAAAGCGTGTATCCCGAGCGAGCATCGAGGCAATCGCAAGCCTCTGTTTCTGGCCTCCTGAAAGGTTCAGCGGGTCTTCCTTTTCGAGACCGGAGAGTCCCACCAGTTCCAGGACCTTCTTTATTCTCTTTCTCATTTCGCTCTCGTCGAGCCCCATTATCTCCAGCGAAAAGGCCACGTCCTCCTCCACGGTGGCACCTATGATCTGTGAAGACGGATTCTGGAAGACGTAGCCCACGTTCTTTCTCAAAAGAAACGGATCCGCTGGTGAACCGTCCAGGAAAATCTCTCCCTCGGCTTCCAGGAGTCCTGCGAGGATCTTCAAAAGGGTGGTCTTCCCGGAGCCGTTTTTTCCCACCACAACGTAGATCTTCCCCGTTTCGAACTCGGCGTTCACGTCCTTCAAAACGTAGTCTCCGTTGTATCTGAAGGAAACGCTATTCAGCGTTATCTTCAT

Protein sequences of DBSCAN-SWA_4

>NC_021214|1643407:1651020|1643407_1644646_-|WP_004082162.1|DBSCAN-SWA
MSVFLFVIVAVLFVLLFLVFKKRLSEYKILIEKLSDMLGEKGVPPLYLFERLKKYVDNLKETISRVEVSRDNFLTILNSLSEPIFILDREGKITFLNEIARELVQGRINPEGRPYYEIFEDYYINEMVEETIKSEEPQEGTLVTYVGNEKKYFHVKVIPVELKSGDKIFVILFHDVTKERKLDEMRREFIATVSHELRTPLTSIHGYAETLLEDDLENKELVKRFLKIIEEESARMTRLINDLLDLEKIEESEANFEMKDVDLCEVIEYVYRIIQPIAEENEVDLIVECEDVVVRGNKERLIQMLLNLVDNAVKYTSLKEKGEKKVWVRAYDTPDWVVVEVEDTGPGIPKEAQSRIFEKFYRVDKARSRKMGGTGLGLTIVKTIVDKHGGKIEVESEINQGTLMRVLLPKRR
>NC_021214|1643407:1651020|1646160_1646451_-|WP_004082168.1|DBSCAN-SWA
MPNIKSAKKRVRVSEKRRLRNKAYKTFFKNRIKEVLKAIENKEPKEVVLELTRKAQAAIDKAVSKGVIHKNQGARRKARLFEKVNEYLRTLETTQE
>NC_021214|1643407:1651020|1648058_1649030_-|WP_004082174.1|DBSCAN-SWA
MKRWLLLISLMVFSAVVFSFSAPVDSPRVSATFGEYRGSGNRGPHFHMGIDFSTGLKEGVPIYASERGWLVRIEIDEDDIYGYTVVLEHENGYRTLYAHLSRFSKKLETVASSLKQEFGNVRIVVNFPEKEIWFEKGEVVGYSGTTGEAPIPHAHFEIRDRNEEVSYDPSTFLNLPKPVDEDIVLEKIKIGDSVYDFVEGRTYPFSGNFPDLAIKAYSKGFNNTLGLKKISLLLEGEEIYQISFDQIPWSEFTNVWGVYDRKSVSAAYRFELWYKLFPETFSSMIKVNKFPELGKAPDFAKYTVVIEDIWGMKKEFSFYLQRR
>NC_021214|1643407:1651020|1644649_1645369_-|WP_004082164.1|DBSCAN-SWA
MAKKKILVVDDDPAILELVGYNLSKEGYEVLKAYDGEEALKIANDEDVDMFIVDIMLPGIDGFELVRKIRSMEKYKNTPVIFLSAKGEEFDKVLGLELGADDYITKPFSVRELLARVKAIFRRLSTATQSKEERPKKIIAKDLEIDVEKYEVKVRGKKVNLTPLEFELLRFLAENEGKVFSRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKED
>NC_021214|1643407:1651020|1647727_1648054_-|WP_004082172.1|DBSCAN-SWA
MLFLFFGKKKKDLNKNPFYREKGSLVVYIKCDRCGEVFRSHLRTGYDFIVDYDNPGVPYKIDKLYVGSKCPNKIHLVATFTSSYKPVSVSLEGGTFITREEFEESQKQ
>NC_021214|1643407:1651020|1649043_1649538_-|WP_004082176.1|DBSCAN-SWA
MYRIRVFGDPVLRKRAKPVTKFDENLKKTIERMIETMYHYDGVGLAAPQVGISQRFFVMDVGNGPVAVINPEILEIDPETEVAEEGCLSFPEIFVEIERSKRIKVKYQNTRGEYVEEELEGYAARVFQHEFDHLNGVLIIDRISPAKRLLLRKKLMDIARTVKR
>NC_021214|1643407:1651020|1646466_1647654_-|WP_004082170.1|DBSCAN-SWA
MRRLFTSESVTEGHPDKIADQISDAILDAMLEQDPRSRVAVETLVTTGLVIIAGEVTTRAYVEIPDIARKTILEIGYTRAKYGFDGETCGVLTSIHSQSPDIALGVDKALEVKTGEEVADEFEALGAGDQGIMFGYATNETPEYMPLPITLAHKLAMRLAEVRKNGTLPFLRPDGKTQVTIEYEDDKPVRVDTVLISTQHDPDISQADLREAIIEHVINPVIPEQYRDDKMKILVNPTGRFVLGGPMADTGLTGRKIIVDTYGGWVPHGGGAFSGKDPTKVDRSAHYMARYVAKNVVAAGLADKFLIQLSYAIGVAKPVSIMIDTYGTAKVDEDKLLKVITELFDFRPGAIIKKLNLLRPIYRKTAAYGHFGRNEEEFTWEKLDMVDELKRAFNM
>NC_021214|1643407:1651020|1649537_1650281_-|WP_004082178.1|DBSCAN-SWA
MRILVTNDDGIQSKGIIVLAELLSEEHEVFVVAPDKERSATGHSITIHVPLWMKKVFISERVVAYSTTGTPADCVKLAYNVVMDKRVDLIVSGVNRGPNMGMDILHSGTVSGAMEGAMMNIPSIAISSANYESPDFEGAARFLIDFLKEFDFSLLDPFTMLNINVPAGEIKGWRFTRQSRRRWNDYFEERVSPFGEKYYWMMGEVIEDDDRDDVDYKAVREGYVSITPIHPFLTNEQCLKKLREVYD
>NC_021214|1643407:1651020|1645429_1646092_-|WP_004082166.1|DBSCAN-SWA
MEGLIGDFFRLIIKNWYFSLPAALFLMFAARYVEHIAFAVIGFVIGINFVFPLLSNIEFLKSYLTNENVKVVVLVATGVLTAVVLYVLYRYLVFLAALVTVTFVAYYVINFLVSSFNLQSVQYMNWITFGLSVFIGLLAGLTAYRKEKEFARILSVVVGAAIFSVLVLFYLSGLFGVEFKPESLFANKMMIFFYVSLFLLFLFLSAWFTFRKRSYQKTSS
>NC_021214|1643407:1651020|1650240_1651020_-|WP_004082181.1|DBSCAN-SWA
MKITLNSVSFRYNGDYVLKDVNAEFETGKIYVVVGKNGSGKTTLLKILAGLLEAEGEIFLDGSPADPFLLRKNVGYVFQNPSSQIIGATVEEDVAFSLEIMGLDESEMRKRIKKVLELVGLSGLEKEDPLNLSGGQKQRLAIASMLARDTRFLALDEPVSMLDPPSQREIFQVLESLKNEGKGIILVTHELEYLDDMDFILHISNGTIDFCGSWEEFVEREFDDVEIPFKWKLWKKCGKINLWEDRYENSGNQRRRDTV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004082162.1|1643407_1644646_-	PAS domain-containing protein	W8CYF6	Bacillus_phage	1.1e-35	36.7
WP_004082164.1|1644649_1645369_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.5e-43	44.3
WP_004082166.1|1645429_1646092_-	hypothetical protein	NA	NA	NA	NA
WP_004082168.1|1646160_1646451_-	30S ribosomal protein S20	NA	NA	NA	NA
WP_004082170.1|1646466_1647654_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	2.0e-138	65.3
WP_004082172.1|1647727_1648054_-	hypothetical protein	NA	NA	NA	NA
WP_004082174.1|1648058_1649030_-	M23 family metallopeptidase	D7RWE0	Brochothrix_phage	3.0e-07	30.8
WP_004082176.1|1649043_1649538_-	peptide deformylase	A0A067XQZ3	Caulobacter_phage	1.8e-21	44.7
WP_004082178.1|1649537_1650281_-	5'/3'-nucleotidase SurE	NA	NA	NA	NA
WP_004082181.1|1650240_1651020_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.2e-24	33.0

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NC_021214|1798317:1806260|DBSCAN-SWA
AGTGCGAAAATACGTGTGGATAGTCGTTTTCATCGTGCTGGGAATCTACTTTCTCACCGGTGTGTATCAGGTAGGACCCTCCGAAGTCGCCCTCCTCAAGACTTTTGGAAGATTCACCTCGGTCGTTCCTTCAGGAATCCACTACCACCTGCCGTATCCGATTCAGTCTCATGTGACCGTCGACGTCACAACTGTGAGAAAGATCGAAATAGGATTCAGAAGCATTCAACGAGGGGAGAGGATCTCTTACCAGTCGGTTCCTCAAGAAGCCATAATGATCACAGGAGACAACAACCTCGTGAGTGTGGAAGCGGTGGTTCAGTACAGGGTGAAAGACCCCGTCGCTTACGCCTTCAACATCACAGAAGCGGATTCCATCGTGAGATTCACAACAGAATCTGTTCTTCGTGAGAAGGTAGCGATGAGAAGCATCGACGACGTTCTCACCTCAGGAAGAGATGAAATAGGATTCAAAACTGCCCAAATGCTCCAGGAGATTCTCGATTCCTACAACTGCGGTATAAAGGTGGAAAACGTTTATCTCCAGGAAGTGGTCCCGCCAGATCCCGTTGTTGACGCCTTCGACGATGTGAACAACGCTCGTCAGGACAAAGAACGTCTCATAAACGAGGCAAGAAAATACGCCAACGACGTTGTTCCAAAAGCCCAGGGACAGGCACAAGAGATACTGAGACAGGCAGAGGCCTACGCTCAGGAAGTTTATCTGAAAGCACTCGGCGAAGCGAAAAGATTCGAAGAGGTGCTGGAAGAATACTCAAAGGCTCCTGATATCACGAGAAAACGAATGCTCCTCGACGCTCTCCAATCTTTGCTTGAAAAATCCGAAAACAAGGTTTTCTTCGTGGGAAACGGTGATTCTCTGAACATTCTCAACATTTCCGACCTTCTGAAGGGGATGGGAAAATGAAAATCTGGATGATTTCTCTTCTGATCATTCTGATCGTGGTGGGTGCGATCCTTCTTTTCTCTTCTTTCTACGTCCTGGATCAGACACAGCAAGCGGTGGTTCTGAGGTTCGGAAAGATCGTCGCGGTGGAAACAGAACCTGGGCTTCACTTCAAGCAGCCGTTCGTTGATAATGTGGTGAGATTCGATAAAAGAATCCTCCTCTACGATATAGAACCAGAAAAGATCATAGCCGCCGACAAGAAAACGCTCGTGATAGACACGTACGTTCTCTGGAGGATAAAAGATGCGGAAGCGTTCATAAAATCACTGAAGAGCGTGAAGCTCGCTCTTCCAAGAATCGACGATGTGGTTTACTCACACGTGAGGAACATCTTCGCAAAAGCGAACTTCGACGAGATCATCTCCGAGAAGAGAGAAGACCTTTTGAGGGAAGTCACGGCTCTTTCAAGAGAAGATCTGAAGGACTTCGGCATAGAAGTGGTCGATGTGAGGGTGAAGCACGCCGACCTCCCCGCTGAGAACGAAAAGGCCGTGTACGAAAGAATGAAAGCGGAAAGATACAGCATCGCTGCACAGATCAGGGCTGAAGGTGAGAAAGAGGCAAGAAAGATACGTGCGGAAGCCGACAAAACAGCGAAGGTTCTGATCGCGGAAGCTCAAAGCAAAGCAGAGCAAATCAAGGGAACCGGAGAAGCAAGCGCGGTGAAGATCTACGCGGAGGTGTTTTCAAAAGACAAGGACTTCTACGAATTCTGGAGAACGATGGAGGTTTACAGATCCATCGAGAAAGGAATTCTCATAATTGGAGACGAACTCGATGCACTGAAATACCTCAAAACGAAGTAAGGGAGAGTTCCCTCACTTCATTTTCAGAAAGTTACTCACGCTGAAGAGCATTCTGAACATCCATATGTTGAACTTGTTTACCCTGTTCTTTCCGGGGCCGTAACCGAAATCTTTCACCGGTCTGAGAAATCTGTACCTCCCAGCGTTGTGAACGATGGGAATGAGCTCACCATTTTCGAGATAGAACTTCGAATCTTTCACGTAGAATTTTTCTCGGGCCGTTGAAGGAATGAAGTTGTACTTCGAAGGAAGTTCCACATGAGGGTTCTTGTAGATCACGTAGTTTCCAATGACAGTATCTCCACCCCAGACGTTTATGTTTTTCAGACGTCTCTCCATTGTTCTTGCGAGCTCGAGGAAACCTTCCCTTGGTGCTATTATCACACCCACGTTGAAGAGCTTTTTGTTTGAAAGAAAAGACTTTATCTCCTTTCCATTCACAAGGTCTTCTTCCTTCACCACGAGATCAATGGGTGGACTCAACTGCTCCACAACCGCTCGAAAAGCATCTCTGTGTTCCTCGAATAGGTGCGAGATGTCACTCTGGAAGATGATGTCTCCGCCATCACAAAACAGGATCTGATCGTACTCAGGATGATTCTCAAGAAAAATGGCAAGATTGATGAAACGCGTGTTGTTTATGAGTCCAGAACGCTCCACAGCCGGAAAGTTGATAACCTCTTTAGGAAGTCCTGTGAGACCGTAGTTTATGACGAGAACGTCCGTTTTGCTCAGATCCACATTTTCCTTCAGAGATCTGTACCAGTCGTTCACAAGAAAGTCCCTTATTCTGTCGTTACCTGCCGTTGCTATCAGATTCAAAAACATCCCTCCTGAGTCTCTTTCTGAGATTTGCCATTTCGATCGCTACCATCGCTGCTTCAAAACCTTTGTTTCCACTCTTTGCTCCGGCTCTGTTGAGGGCCTGTTCAAGGGTGTCCGTGGTGAGAACGCCGAAAACAATAGGAATATCAGAGGTCATGTTGAACTGCGCCACTGCTTTACCTATCTCGTTCGCCACCACGTTGAAGTGGTACGTCTCTCCCCTTATCACAGCACCGAGAACGATTATAGCATCATGCACACCGAGATCGAGGAGTCTCTTGAGCGTGTATATCGCTTCCATACTTCCCGGAATTCTCACAACCGTTATGTTCTCGTCTGAGACACCGTGTCTTTTCAGCCCGTCGAGCGCTCCCTCGAGGAGTTTCGAAGTGACAAGGTCGTTGAACCTAGGAACGACTACGGCTATCTTCAAACCTTCTCCTCTGTAGTCTCCCTGAACAACCTTCATGAATTCACCTCCCTGAAGATTTCTTCGAGTTCGTGTCCGAGCTTTTTCATTTTTGTCGAAAGATAGAACCTGTTGTGAGGTGTTACTCTTCCGTACAGTCTCTTCGTTTCGACAACTTCGATCCCGTATTTTTCAAGACCAACCGTCTTTCTTTGGTTGTTGGTGAAGAGAAGAACCCTTTCGATGCCAAGGGCTTTCAAGATCTGCGCTGCCGGTGCGTAATCTCTTTCGTCTTCAGAAAAACCAAGAACTCTGTTTGCCTCCACCGTGTCCAAACCTTTGTCCTGAAGAGAATAGGCTGCAATTTTGTTCGAAAGGCCGATTCCTCTCCCTTCCTGTCTCAAATAGATCAGGATACCTCCGTGAGCTGACATGTATCTGAGAAAATTCGCCAGCTGTGAACCGCAGTCACACCTCAAAGAAGAGAGAACATCCCCGGTCACGCATTCGGAGTGTATTCTCACAGCAACGGGATCTTCGAGGGGTTCCTTAACGATTGCGAAGTGTTCTTTGCCATCGAGGTGGTTTTCGAAAGAAACAACCTTGAAGACACCGAAATCCGTTGGAAGTGTTGCTTCTGCTTTTTTCTTCATGAGAAGCTTTCTCTTCACAAATTCACGCCAGACATCGTCCATCTCCAGAACGGGGAGGGAAAATTTTTCTGAGAGCTTCAAAACATAATCCAAATTGTGAGAATTTCCCTTCTCATCCAGAATTTCCACGATCACGGCGTGACGGCTGAAGCCCGCGAGCTCAGAAATTTCCAGAGATGCCTCCGTGTGTCCTTTTCGTCTCTGGAAACCGATTCCTCCTATCACCGTGACGTGACCCGGGTATCTGAACTCATGAAAATACCTGCCTTCTGCAAGCTTTCTGCACGTTTCTGCCCTCTCCAACGCTGAAATCCCCGTGCCAGTGCCCCAGTCCACCGGCACGAAGTAGTTCGCTCCGTAGTTCGAGGAAAGTTTTACGAACCCTCTCTTCAAAAGATCTTCCTCGTCGGCTGTAACACAGAAGAGTCCCTTTCCATATGTAACGAAAAAGCTCACAACGTCTTCGGTGATCAGTTGAGCGGGAAAAACGAAATCTGCTTCGTTCTCTCTATTTCTGTCGATCAAAATGACGGGCTTTCCTTCCTCAAAAGCCTCTCTCAGTTCTTCCACGGTCTATCACCCCTTTCAGGTAGCGAGCGATGATATCGATCTCGTAGTTAACGGGATCTCCGGGCACCAGATACTGGAGGTTCGTGTTCTCGAACGTGTGTGGGATCACCTGAACACTGAACGTGTCCAGAGAAGTTTCAACGACGGTGAGGCTGATACCGTTCAACGTGATAGAACCTTTTGGAACGATCGCCCATCTTTCCGACGGCATCGAAAAGAACATGAAATAGCTGTTTCCGCGCCTTTCCATTCCGACAAACCTGACGGTACCGTCCACATGGCCTGTTACCAGGTGTCCTTCAACTCTGCTGCCGAGAGCCAGAGATTTTTCAAGATTGTAAAAACGAGAAACGAAAAGATTGGTTCTCCTCCTCGTTTCCTCACCCACATCGAACCAGTACTCTTCTTCTGAAAGCCCGGAGACAGTCAGACACACACCGTTCACCGCTATACTCTCTCCCAGTTTCACTTCCCACGTTCTTTTGAAGAAGATCCTCTCTCCTCTGATGTGCCCTCTTTCCACCTTCTGAACTATTCCCGTGAACACGGTCTCATCTCCACCAGAAACTCCGAATCGGAAAACTCCACGTTCACCACTTTGAACTTCGGAGGAACCGAAACATCTGACAGATAACCGGAGAAGACATCAAGCCCCTTTCCGAAAATCTTCGTCGAATAAAAACCAAAAACCACATCTGCGTGATCCAAAAATTCACTGAACACCTTCGATCCGCCTTCCACCAAGACAGAATCGATATCCCTTTCATACAGATTTCTCAATATACTCTCCACAGAACAATCGCTCAGGGCCTTCTCCACGTGTGGTGGATATTCCGCCTCTTCACTTTCTGTGAAAACGATCACCCGAGCGTTTTCTTCGAACACTCTGAACACTTTCCCACTCAAAACACCCTTTCTGTCGAGGATCACCCTCACAGGATTTCTGCCTTCTTTCAGTCTGCAGGTTAGCTGAGGATTGTCCTTCAAAACCGTTCCAGCACCGACGAGAACAGCAGAGTAGATGTTTCTCATCTCGTGAACCTTGAATCTGAGTTTGTCTGTGATCCACTTGGAATCTCCTCTGTGATCAGCTATTTTCCCATCTAAGGTGGACGCGTACTTCAGCGCAACGAACGGCCTTTTCTTTGTCACATAAGTGATGAAAAACTCACACAGCTTTTTCACCTCTTCTTCCAAAACACCTTCTATCACTTCAATACCGTGATTTCTGAATTTTTCCACACCGTTTCCCGAAACAGGATTTGGATCCCTTGTTCCAATCACAACGGTTTTTATTCCACTTTCTATGATCAGATCCGTGCATGGAGGTGTCTTTCCATGATGATCACAGGGTTCAAGGGTAACTATGAGAGTTGCACCTCGTAAATCTTCTCCTTTCTTTCTTGCACTTTCTATTGCCATCCTTTCAGCGTGCGGACCTCCAAAATAGGGATGAAAACCCTCCGCGATTATCCTGCCGTCTTTCACAACGACCGCACCAACTGGTGGGTTGGGATTCACCCTTCCAAGTCCTTTCTTTGCAAGCTCTATCGCTCTTTTCATGAAAGTTTCATACATACAACACCCTCCCTGTGTAAAAGAAAAGGGACCCTCTCGGGTCCCATATAACCTCCACATCACGCTCTCTCCCATCCGGACTTTCACCGTCGGCCCCGGAATTCCACCGGGTCAACCCTCCTGAGAGGGCTCGCGGGCTTTCACCGCCGGTCGGGAATTCCACCCTGCCCCGAGAGCGTTTCTTTTGTATTCAGTTTTCTCCATTCTATCAAGGATTTATTTCCAGAAGGTGAACAGATCTTTTAACTTCATCTGCCGATCACTCTGTTTTTTCCACGCTGTTTTGCCAGATAGAGGTTATCGTCTGCTTCTTTGAGAAGATCGTCTATTGTCTCATGATCTTTCATTTCGCAAACACCGATACTCACGGTTACATTCAAGCCGTTTTCAAAGACTTCTTTCTCGATCTTAGTCCTGATTCTCTCAGCGAGGCTCACCGCTTCGTTCAACTTCGTTTCAGGACAGAGGATCAAAAACTCTTCTCCACCCCACCTCGCAATCACTTGACCTCCTCCCAATCCCCTGAAGGGGATGGGATTCTTGGTGGCTCTCAGGCCACCTTCCATGGAGCCAAAGATGCTCCATGGCCACAGAGGTGCGGATGAAACCTCACACCTCTGACGGGGGCCAAACCCGCTACTACCTGGCCTGTGCCAGGATACCTTTTCCAGATGTTGATTGCTCCAACTCCGTCCCTGTGATACTCAAAACCACAGGTTTTGCAGTGGTATCTTCTTCCGTTCGGCTTGTTCTTTGCACCACAGACAGGACACGTCTTGCTCGTGTTCGCTTCTGAAATGAGTTCCACTTCGATTCCGAACTGCTCTGCTTTGTACCTTATCATCTCGATGAGTTTTCTGAACTGCCACTGGTGGATCTTCTGGTTCGCATTGTCGCTATAGTCCGCTCTTTCTCTGATCCCTGTGACGTCTCCTATCACGATGGTTCCGATTTGTTTTCTGAGGCACAGTCCGATGAAACTGCTTGTGATCTTGTGCATGATGTCGTTGATCTGGTTTCTGAGCCGTCTCAGGACTCTTTTCTTTGCACGAACAAGCTTGTTGTACCTTCTTGATCCCTTCTTGCACTCTGCTATGGCAGACTGAAAACTTGCGAGGCGTTTGTTTCGGTAGCGAAGGATGCTGCTAAGAACCCCTCCGTGGTAGCTGATGACTTCTTTTCCATCAAAGCACGTGATGGGACGGAGCACTCCAGGGTCGACTGCCATAACACCAGAATTAGCACTCTTTTCTTCAATCTCCACCTCTATCGCAAGGTGGAGATAGTATCCATCTTCAAAGACAAGTCTTGTCTGTTTGATGCGAAGGGGAGGTTTGAGAGGTGTTTGTACAACAAATGGTTCTCGTTCTTTGCCCAAAGACAATCTCAGGGTGCCGTCTGGCAGAAGTTTTACAGCGCTTTCTTTCCATATGAACGGCAGATAGCGTTTTTTCTTGTAGGGAGGTTTTGCATCTGGATTCTTTTTGGTTGCTTTGAAGTACCCTTTGAGGGCTTGAAAGTAGAGCTGAACAAATGCCTGCTTTGAGTGGACGTGGATTTTGATGTTTTCTGCCCAGCGGAGGATGTATTTGTCTGCGGTGGGCCAGGACAGCCAGAAGCCTTTCTTTTGGTGTATCTTTCGCACAAGAGACATCGTTTTGTTGTAGATTCTTGCTGCTGTGCGGTTGAGTTCTTCGCATGTTTGACTCAGGTGTCCTGGTACGGCGAGTTTGTAGGTTCGTATCACACGTCTTGACATTCCTCGATGTACCTCCTGATAGTTTCTTCAGAAACATTACCGGCTGTTCCAACGTAGTAACTTCGAGCCCAAAGGCCCTCTTTGGTTCTAAGCTCTGGAAATTTCTCCAGCAGTTTCCTCGCTGAAACGCCCTTGAACAGGTTTGCTATCTCAGCCGGTGAAAATCTTGGAGGCGCCGATACAAACAAATGAACATGATCAGGCTGAATAGAGAGGGCCAGTATTTCTATTCCGTGTTGTTTTGCTGTGTTGCGGAGTATTCGTTCAAGTTCTTCAGCTATGGAGCCGACCAGGATTTTTCTGCGGTATTTAGGTATCCACGCAAAATGATAGTTCAGATTATAATGACTCCACCTTGTCTTCTTGATATGCAT

Protein sequences of DBSCAN-SWA_5

>NC_021214|1798317:1806260|1798317_1799244_+|WP_004082368.1|protease|DBSCAN-SWA
MRKYVWIVVFIVLGIYFLTGVYQVGPSEVALLKTFGRFTSVVPSGIHYHLPYPIQSHVTVDVTTVRKIEIGFRSIQRGERISYQSVPQEAIMITGDNNLVSVEAVVQYRVKDPVAYAFNITEADSIVRFTTESVLREKVAMRSIDDVLTSGRDEIGFKTAQMLQEILDSYNCGIKVENVYLQEVVPPDPVVDAFDDVNNARQDKERLINEARKYANDVVPKAQGQAQEILRQAEAYAQEVYLKALGEAKRFEEVLEEYSKAPDITRKRMLLDALQSLLEKSENKVFFVGNGDSLNILNISDLLKGMGK
>NC_021214|1798317:1806260|1800104_1800914_-|WP_004082370.1|DBSCAN-SWA
MNLIATAGNDRIRDFLVNDWYRSLKENVDLSKTDVLVINYGLTGLPKEVINFPAVERSGLINNTRFINLAIFLENHPEYDQILFCDGGDIIFQSDISHLFEEHRDAFRAVVEQLSPPIDLVVKEEDLVNGKEIKSFLSNKKLFNVGVIIAPREGFLELARTMERRLKNINVWGGDTVIGNYVIYKNPHVELPSKYNFIPSTAREKFYVKDSKFYLENGELIPIVHNAGRYRFLRPVKDFGYGPGKNRVNKFNIWMFRMLFSVSNFLKMK
>NC_021214|1798317:1806260|1805870_1806260_-|WP_008194358.1|transposase|DBSCAN-SWA
MHIKKTRWSHYNLNYHFAWIPKYRRKILVGSIAEELERILRNTAKQHGIEILALSIQPDHVHLFVSAPPRFSPAEIANLFKGVSARKLLEKFPELRTKEGLWARSYYVGTAGNVSEETIRRYIEECQDV
>NC_021214|1798317:1806260|1802523_1803096_-|WP_004082373.1|DBSCAN-SWA
MFTGIVQKVERGHIRGERIFFKRTWEVKLGESIAVNGVCLTVSGLSEEEYWFDVGEETRRRTNLFVSRFYNLEKSLALGSRVEGHLVTGHVDGTVRFVGMERRGNSYFMFFSMPSERWAIVPKGSITLNGISLTVVETSLDTFSVQVIPHTFENTNLQYLVPGDPVNYEIDIIARYLKGVIDRGRTERGF
>NC_021214|1798317:1806260|1804375_1804693_-|WP_010865413.1|DBSCAN-SWA
MEGGLRATKNPIPFRGLGGGQVIARWGGEEFLILCPETKLNEAVSLAERIRTKIEKEVFENGLNVTVSIGVCEMKDHETIDDLLKEADDNLYLAKQRGKNRVIGR
>NC_021214|1798317:1806260|1799240_1800092_+|WP_004082369.1|protease|DBSCAN-SWA
MKIWMISLLIILIVVGAILLFSSFYVLDQTQQAVVLRFGKIVAVETEPGLHFKQPFVDNVVRFDKRILLYDIEPEKIIAADKKTLVIDTYVLWRIKDAEAFIKSLKSVKLALPRIDDVVYSHVRNIFAKANFDEIISEKREDLLREVTALSREDLKDFGIEVVDVRVKHADLPAENEKAVYERMKAERYSIAAQIRAEGEKEARKIRAEADKTAKVLIAEAQSKAEQIKGTGEASAVKIYAEVFSKDKDFYEFWRTMEVYRSIEKGILIIGDELDALKYLKTK
>NC_021214|1798317:1806260|1801382_1802549_-|WP_004082372.1|DBSCAN-SWA
MEELREAFEEGKPVILIDRNRENEADFVFPAQLITEDVVSFFVTYGKGLFCVTADEEDLLKRGFVKLSSNYGANYFVPVDWGTGTGISALERAETCRKLAEGRYFHEFRYPGHVTVIGGIGFQRRKGHTEASLEISELAGFSRHAVIVEILDEKGNSHNLDYVLKLSEKFSLPVLEMDDVWREFVKRKLLMKKKAEATLPTDFGVFKVVSFENHLDGKEHFAIVKEPLEDPVAVRIHSECVTGDVLSSLRCDCGSQLANFLRYMSAHGGILIYLRQEGRGIGLSNKIAAYSLQDKGLDTVEANRVLGFSEDERDYAPAAQILKALGIERVLLFTNNQRKTVGLEKYGIEVVETKRLYGRVTPHNRFYLSTKMKKLGHELEEIFREVNS
>NC_021214|1798317:1806260|1804677_1805886_-|WP_004082376.1|transposase|DBSCAN-SWA
MSRRVIRTYKLAVPGHLSQTCEELNRTAARIYNKTMSLVRKIHQKKGFWLSWPTADKYILRWAENIKIHVHSKQAFVQLYFQALKGYFKATKKNPDAKPPYKKKRYLPFIWKESAVKLLPDGTLRLSLGKEREPFVVQTPLKPPLRIKQTRLVFEDGYYLHLAIEVEIEEKSANSGVMAVDPGVLRPITCFDGKEVISYHGGVLSSILRYRNKRLASFQSAIAECKKGSRRYNKLVRAKKRVLRRLRNQINDIMHKITSSFIGLCLRKQIGTIVIGDVTGIRERADYSDNANQKIHQWQFRKLIEMIRYKAEQFGIEVELISEANTSKTCPVCGAKNKPNGRRYHCKTCGFEYHRDGVGAINIWKRYPGTGQVVAGLAPVRGVRFHPHLCGHGASLAPWKVA
>NC_021214|1798317:1806260|1800888_1801386_-|WP_004082371.1|DBSCAN-SWA
MKVVQGDYRGEGLKIAVVVPRFNDLVTSKLLEGALDGLKRHGVSDENITVVRIPGSMEAIYTLKRLLDLGVHDAIIVLGAVIRGETYHFNVVANEIGKAVAQFNMTSDIPIVFGVLTTDTLEQALNRAGAKSGNKGFEAAMVAIEMANLRKRLRRDVFESDSNGR
>NC_021214|1798317:1806260|1803080_1804127_-|WP_004082374.1|DBSCAN-SWA
MYETFMKRAIELAKKGLGRVNPNPPVGAVVVKDGRIIAEGFHPYFGGPHAERMAIESARKKGEDLRGATLIVTLEPCDHHGKTPPCTDLIIESGIKTVVIGTRDPNPVSGNGVEKFRNHGIEVIEGVLEEEVKKLCEFFITYVTKKRPFVALKYASTLDGKIADHRGDSKWITDKLRFKVHEMRNIYSAVLVGAGTVLKDNPQLTCRLKEGRNPVRVILDRKGVLSGKVFRVFEENARVIVFTESEEAEYPPHVEKALSDCSVESILRNLYERDIDSVLVEGGSKVFSEFLDHADVVFGFYSTKIFGKGLDVFSGYLSDVSVPPKFKVVNVEFSDSEFLVEMRPCSRE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004082368.1|1798317_1799244_+|protease	FtsH protease activity modulator HflK	S4VT23	Pandoravirus	2.3e-09	26.5
WP_004082369.1|1799240_1800092_+|protease	protease modulator HflC	NA	NA	NA	NA
WP_004082370.1|1800104_1800914_-	hypothetical protein	NA	NA	NA	NA
WP_004082371.1|1800888_1801386_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.2e-30	44.7
WP_004082372.1|1801382_1802549_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	8.1e-68	38.2
WP_004082373.1|1802523_1803096_-	riboflavin synthase	A0A2I2L4R9	Orpheovirus	8.6e-23	35.5
WP_004082374.1|1803080_1804127_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.5e-52	37.2
WP_010865413.1|1804375_1804693_-	GGDEF domain-containing protein	G3MA91	Bacillus_virus	7.7e-05	31.0
WP_004082376.1|1804677_1805886_-|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1C9EG34	Acidianus_two-tailed_virus	3.6e-10	26.6
WP_008194358.1|1805870_1806260_-|transposase	IS200/IS605 family transposase	W0UUZ0	Sulfolobus_monocaudavirus	8.4e-38	56.8