CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_021251	Mycobacterium tuberculosis CCDC5079, complete sequence	13 crisprs	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	8	25	2	0

1. NC_021251

CRISPR-Cas detection and classification

Crispr_ID: NC_021251_1

• CRISPR_ID: NC_021251_1
• CRISPR_location: 364874-365572
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 10 spacers

Consensus repeat of NC_021251_1

Consensus_repeat	Method
TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	CRISPRCasFinder

spacers of NC_021251_1

>1.1|364907|27|NC_021251|CRISPRCasFinder
AACGCACCGGTGTCCACATCGCCCGTG
>1.2|364967|27|NC_021251|CRISPRCasFinder
AGGTAGCCCGTGTTGCCACTGCCCGGG
>1.3|365027|42|NC_021251|CRISPRCasFinder
AAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTG
>1.4|365102|27|NC_021251|CRISPRCasFinder
AAGCCGCCCGAGTTCGCGAGACCGAAG
>1.5|365162|42|NC_021251|CRISPRCasFinder
CCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAG
>1.6|365237|33|NC_021251|CRISPRCasFinder
AGGCTGCCGATCCCGATCTGGCCGTTGCCGGTG
>1.7|365303|27|NC_021251|CRISPRCasFinder
GCGAAGCCGATGTTGTAGCTGCCGGTG
>1.8|365363|57|NC_021251|CRISPRCasFinder
GCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGA
>1.9|365453|27|NC_021251|CRISPRCasFinder
GCCAAGCCGATATCGAAGATCCCGGTG
>1.10|365513|27|NC_021251|CRISPRCasFinder
ACCCCGCCGAAGTTGAGGTCGCCGAGG

CRISPR arrays and Neighbor proteins around NC_021251_1

CRISPR arrays

The CRISPR arrays of NC_021251_1

>merge|NC_021251|1|364874-365572|CRISPRCasFinder
ACCAAGAAGCCGTTGCTGTAGCTGCCGGTAATGAACGCACCGGTGTCCACATCGCCCGTGTTCGCCACGCCCGTGTTGTAGTCACCGGTGTTGAGGTAGCCCGTGTTGCCACTGCCCGGGTTGAAGCCGCCGGTGTTGAAGCTGCCCGGGTTGAAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTGTTGGTGCTGCCCGCGTTGCCGATGCCGGTGTTGAAGCCGCCCGAGTTCGCGAGACCGAAGTTGCCGGTGCCGGTGTTAAAGATGCCGACGTTGCCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAGTTGAACAGCCCGATGTTGTTGCTGCCCGAGTTGAGGCTGCCGATCCCGATCTGGCCGTTGCCGGTGAGCCCGACGCCGATGTTGTTGTTACCGGTATTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTGGCAAAGCCCAGGTTGTCGCTGCCGAAGTTCGCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGATTTGCCAACCCGATGTTGTAGCTGCCCAGGTTCGCCAAGCCGATATCGAAGATCCCGGTGTTGGCGATGCCGATGTTGTTACCGCCGATGTTGACCCCGCCGAAGTTGAGGTCGCCGAGGTTGCCGATGCCCAGGTTGGAGTCGCCGGTATTA

>NC_021251|1|1|364874-365572|CRISPRCasFinder
ACCAAGAAGCCGTTGCTGTAGCTGCCGGTAATG	AACGCACCGGTGTCCACATCGCCCGTG
TTCGCCACGCCCGTGTTGTAGTCACCGGTGTTG	AGGTAGCCCGTGTTGCCACTGCCCGGG
TTGAAGCCGCCGGTGTTGAAGCTGCCCGGGTTG	AAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTG
TTGGTGCTGCCCGCGTTGCCGATGCCGGTGTTG	AAGCCGCCCGAGTTCGCGAGACCGAAG
TTGCCGGTGCCGGTGTTAAAGATGCCGACGTTG	CCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAG
TTGAACAGCCCGATGTTGTTGCTGCCCGAGTTG	AGGCTGCCGATCCCGATCTGGCCGTTGCCGGTG
AGCCCGACGCCGATGTTGTTGTTACCGGTATTC	GCGAAGCCGATGTTGTAGCTGCCGGTG
TTGGCAAAGCCCAGGTTGTCGCTGCCGAAGTTC	GCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGA
TTTGCCAACCCGATGTTGTAGCTGCCCAGGTTC	GCCAAGCCGATATCGAAGATCCCGGTG
TTGGCGATGCCGATGTTGTTACCGCCGATGTTG	ACCCCGCCGAAGTTGAGGTCGCCGAGG
TTGCCGATGCCCAGGTTGGAGTCGCCGGTATTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003401544.1|358168_359566_-|sulfatase	unknown	unknown	gnl|CDD|293751
NC_021251.1|WP_003401589.1|374967_375450_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003401619.1|381273_381936_-|DUF3060-domain-containing-protein	unknown	unknown	gnl|CDD|371435
NC_021251.1|WP_003902650.1|377566_378796_+|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003401563.1|362236_362458_+|type-II-toxin-antitoxin-system-antitoxin-VapB2	unknown	unknown	gnl|CDD|222832
NC_021251.1|WP_003401566.1|362454_362880_+|PIN-domain-nuclease	unknown	unknown	gnl|CDD|350322
NC_021251.1|WP_003401555.1|361662_361890_+|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl|CDD|279710
NC_021251.1|WP_010886074.1|359744_361520_+|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_021251.1|WP_003401584.1|374308_374980_+|5,6-dimethylbenzimidazole-synthase	unknown	unknown	gnl|CDD|162875
NC_021251.1|WP_003905275.1|363015_363648_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_021251.1|WP_003900119.1|378950_380813_+|Hsp70-family-protein	unknown	unknown	gnl|CDD|223520
NC_021251.1|WP_003900117.1|363644_364553_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187670
NC_021251.1|WP_003401538.1|356581_357367_+|trans-aconitate-2-methyltransferase	unknown	unknown	gnl|CDD|184509
NC_021251.1|WP_003401560.1|361886_362189_+|toxin-antitoxin-system-toxin	unknown	unknown	unknown
NC_021251.1|WP_003401594.1|375507_376224_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486
NC_021251.1|WP_003401540.1|357355_358159_-|hypothetical-protein	unknown	unknown	gnl|CDD|226848
NC_021251.1|WP_003401601.1|377051_377543_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|379275
NC_021251.1|WP_003401597.1|376325_376982_+|L,D-transpeptidase	unknown	unknown	gnl|CDD|226309
NC_021251.1|WP_003401613.1|380884_381271_+|hypothetical-protein	unknown	unknown	gnl|CDD|223403
NC_021251.1|WP_003905279.1|381996_382881_+|family-16-glycosylhydrolase	unknown	unknown	gnl|CDD|225182

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003401544.1|358168_359566_-|sulfatase	gnl|CDD|293751	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase). N-sulfoglucosamine sulfohydrolase (SGSH) belongs to the sulfatase family and catalyses the cleavage of N-linked sulfate groups from the GAGs heparin sulfate and heparin. The active site is characterized by the amino-acid sequence motif C(X)PSR that is highly conserved among most sulfatases. The cysteine residue is post-translationally converted to a formylglycine (FGly) residue, which is crucial for the catalytic process. Loss of function of SGSH results a disease called mucopolysaccharidosis type IIIA (Sanfilippo A syndrome), a fatal childhood-onset neurodegenerative disease with mild facial, visceral and skeletal abnormalities.	5.75322e-137
NC_021251.1|WP_003401594.1|375507_376224_+|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	2.34145e-31
NC_021251.1|WP_003401619.1|381273_381936_-|DUF3060-domain-containing-protein	gnl|CDD|371435	pfam11259, DUF3060, Protein of unknown function (DUF3060). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed.	1.8339e-21
NC_021251.1|WP_003401563.1|362236_362458_+|type-II-toxin-antitoxin-system-antitoxin-VapB2	gnl|CDD|222832	PHA01748, PHA01748, hypothetical protein.	0.00852727
NC_021251.1|WP_003401566.1|362454_362880_+|PIN-domain-nuclease	gnl|CDD|350322	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC3 and VapC21 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.62509e-57
NC_021251.1|WP_003401555.1|361662_361890_+|ribbon-helix-helix-protein,-CopG-family	gnl|CDD|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.000113886
NC_021251.1|WP_010886074.1|359744_361520_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.70979e-29
NC_021251.1|WP_003900119.1|378950_380813_+|Hsp70-family-protein	gnl|CDD|223520	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones].	3.71262e-67
NC_021251.1|WP_003905275.1|363015_363648_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.1641e-15
NC_021251.1|WP_003900117.1|363644_364553_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187670	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs. Classical SDR-like subgroup containing LPOR and related proteins. Protochlorophyllide (Pchlide) reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.69352e-146
NC_021251.1|WP_003401538.1|356581_357367_+|trans-aconitate-2-methyltransferase	gnl|CDD|184509	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional.	8.03642e-167
NC_021251.1|WP_003401584.1|374308_374980_+|5,6-dimethylbenzimidazole-synthase	gnl|CDD|162875	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase. A previously published hypothesis that BluB, involved in cobalamin biosynthesis, is EC 1.16.8.1 (cob(II)yrinic acid a,c-diamide reductase) is now contradicted by newer work ascribing a role in 5,6-dimethylbenzimidazole (DMB) biosynthesis. The BluB protein is related to the nitroreductase family (pfam0881). [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	6.73571e-73
NC_021251.1|WP_003401597.1|376325_376982_+|L,D-transpeptidase	gnl|CDD|226309	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown].	4.28441e-100
NC_021251.1|WP_003401540.1|357355_358159_-|hypothetical-protein	gnl|CDD|226848	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown].	2.12891e-123
NC_021251.1|WP_003401601.1|377051_377543_-|nuclear-transport-factor-2-family-protein	gnl|CDD|379275	pfam13577, SnoaL_4, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.69655e-31
NC_021251.1|WP_003401613.1|380884_381271_+|hypothetical-protein	gnl|CDD|223403	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones].	0.00700797
NC_021251.1|WP_003905279.1|381996_382881_+|family-16-glycosylhydrolase	gnl|CDD|225182	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism].	3.10128e-51

Protein sequences

>NC_021251.1|WP_003900117.1|363644_364553_+|SDR-family-NAD(P)-dependent-oxidoreductase
MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQVT
>NC_021251.1|WP_003905275.1|363015_363648_+|TetR/AcrR-family-transcriptional-regulator
MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEADGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET
>NC_021251.1|WP_003401566.1|362454_362880_+|PIN-domain-nuclease
MTDQRWLIDKSALVRLTDSPDMEIWSNRIERGLVHITGVTRLEVGFSAECGEIARREFREPPLSAMPVEYLTPRIEDRALEVQTLLADRGHHRGPSIPDLLIAATAELSGLTVLHVDKDFDAIAALTGQKTERLTHRPPSA
>NC_021251.1|WP_003401563.1|362236_362458_+|type-II-toxin-antitoxin-system-antitoxin-VapB2
MSDVLIRDIPDDVLASLDAIAARLGLSRTEYIRRRLAQDAQTARVTVTAADLRRLRGAVAGLGDPELMRQAWR
>NC_021251.1|WP_003401560.1|361886_362189_+|toxin-antitoxin-system-toxin
MIAPGDIAPRRDSEHELYVAVLSNALHRAADTGRVITCPFIPGRVPEDLLAMVVAVEQPNGTLLPELVQWLHVAALGAPLGNAGVAALREAASVVTALLC
>NC_021251.1|WP_003401555.1|361662_361890_+|ribbon-helix-helix-protein,-CopG-family
MTKEKISVTVDAAVLAAIDADARAAGLNRSEMIEQALRNEHLRVALRDYTAKTVPALDIDAYAQRVYQANRAAGS
>NC_021251.1|WP_010886074.1|359744_361520_+|PE-family-protein
MSFVIAQPEMIAAAAGELASIRSAINAANAAAAAQTTGVMSAAADEVSTAVAALFSSHAQAYQAASAQAAAFHAQVVRTLTVDAGAYASAEAANAGPNMLAAVNAPAQALLGRPLIGNGANGAPGTGQAGGDGGLLFGNGGNGGSGAPGQAGGAGGAAGFFGNGGNGGDGGAGANGGAGGTAGWFFGFGGNGGAGGIGVAGINGGLGGAGGDGGNAGFFGNGGNGGMGGAGAAGVNAVNPGLATPVTPAANGGNGLNLVGVPGTAGGGADGANGSAIGQAGGAGGDGGNASTSGGIGIAQTGGAGGAGGAGGDGAPGGNGGNGGSVEHTGATGSSASGGNGATGGNGGVGAPGGAGGNGGHVSGGSVNTAGAGGKGGNGGTGGAGGPGGHGGSVLSGPVGDSGNGGAGGDGGAGVSATDIAGTGGRGGNGGHGGLWIGNGGDGGAGGVGGVGGAGAAGAIGGHGGDGGSVNTPIGGSEAGDGGKGGLGGDGGGRGIFGQFGAGGAGGAGGVGGAGGAGGTGGGGGNGGAIFNAGTPGAAGTGGDGGVGGTGAAGGKGGAGGSGGVNGATGADGAKGLDGATGGKGNNGNPG
>NC_021251.1|WP_003401544.1|358168_359566_-|sulfatase
MTSERATGQRENLLIVHWHDLGRYLGVYHHPDVYSPRLDRLAAEGILFTRAHATAPLCTPSRGSLFTGRYPQSNGLVGLAHHGWEYRTGVQTLPQLLSESGWYSALFGMQHETSYPKRLGFDEFDVSNSYCEYVVAKAQDWLHNRVPALDGQRFLLTAGFFETHRPYPHERYRPADSAAVELPDYLPDTPEVRQDVAEFYGSIATADEAVGRLLDTLADTGLDASTWVVFVTDHGPAFPRAKSTLYDAGTGIALIIRPPTRRAMAPRVYDELFSGVDLVPTLLDLLRLEVPADVEGVSHAPALLAPDTENAAVRDHVYTAKTYHDSFDPIRAIRTKEYSYIENYAPRPLLDLPWDIQESPAGMAVAPLVKAPRPQRELYDLRADPTETNNLLAGDDSTQGVAAIAADLAVRLHDWRQRTADVIPSDFAGSRIAERYTETYLRIHRKTPTGRSAIAADRGIDEHCS
>NC_021251.1|WP_003401540.1|357355_358159_-|hypothetical-protein
MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT
>NC_021251.1|WP_003401538.1|356581_357367_+|trans-aconitate-2-methyltransferase
MWDPDVYLAFSGHRNRPFYELVSRVGLERARRVVDLGCGPGHLTRYLARRWPGAVIEALDSSPEMVAAAAERGIDATTGDLRDWKPKPDTDVVVSNAALHWVPEHSDLLVRWVDELAPGSWIAVQIPGNFETPSHAAVRALARREPYAKLMRDIPFRVGAVVQSPAYYAELLMDTGCKVDVWETTYLHQLTGEHPVLDWITGSALVPVRERLSDESWQQFRQELIPLLNDAYPPRADGSTIFPFRRLFMVAEVGGARRSGG
>NC_021251.1|WP_003401584.1|374308_374980_+|5,6-dimethylbenzimidazole-synthase
MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAAPSVGLMQPWRFIRITDETLKRRIHALVDDERLLTAEALGAREEEFLALKVEGILDCAELLVVALCDRRGSYIFGRRTLPQMDLASVSCAIQNLWLAARSEGLGMGWVSLFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELDGWAYARPLAEFVSENRWSYPSALATDHHHGE
>NC_021251.1|WP_003401589.1|374967_375450_-|hypothetical-protein
MAVIVRKWFGLGRLPADLRCQVEAEGLIYLAEYVAVTRRFTGVIPGLRASHSIASYVGALAFTEQRVLGTLSMVPKLAGRVVDARWDGPQAGAATAEISPTGLQLDLDVADVDPKFSGQLALHFKATIGEDVLSRLPRRSLAFDVPAEYVNLAVGVTYSP
>NC_021251.1|WP_003401594.1|375507_376224_+|phosphatase-PAP2-family-protein
MTRPQALLAVSLAFVATAVYAVMWVGHSQDWGWLHSFDWSLLNAAHDIGIKNPAWVRFWDGVSLILGPVVLRPLGLLAAMVALAKRKIRIALLLLACLPLNAIMTIAAKSVAHRPRPATALVSAHSTSFPSGHALEATASVLALLTVLLPMLHSRFTRHIAITVGALCVLTVGVARVALNVHHPTDVVAGWALGYLYFLVCLCVFRPPSIFGAQRASHALSPPVEVSRQPEPEVDTAR
>NC_021251.1|WP_003401597.1|376325_376982_+|L,D-transpeptidase
MSRLLALLCAAVCTGCVAVVLAPVSLAVVNPWFANSVGNATQVVSVVGTGGSTAKMDVYQRTAAGWQPLKTGITTHIGSAGMAPEAKSGYPATPMGVYSLDSAFGTAPNPGGGLPYTQVGPNHWWSGDDNSPTFNSMQVCQKSQCPFSTADSENLQIPQYKHSVVMGVNKAKVPGKGSAFFFHTTDGGPTAGCVAIDDATLVQIIRWLRPGAVIAIAK
>NC_021251.1|WP_003401601.1|377051_377543_-|nuclear-transport-factor-2-family-protein
MCCNGVVTPGDPADIAAIKQLKYRYLRALDTKHWDDFTDTLAEDVTGDYGSSVGTELHFTNRADLVDYLRQALGPGVITEHRVTHPEITVTGDTATGIWYLQDRVIVAEFNFMLIGAAFYHDQYRRTTDGWRISATGYDRTYEATMSLAGLNFNIRPGRALAD
>NC_021251.1|WP_003902650.1|377566_378796_+|hypothetical-protein
MSQSRYAGLSRSELAVLLPELLLIGQLIDRSGMAWCIQAFGRQEMLQIAIEEWAGASPIYTKRMQKALNFEGDDVPTIFKGLQLDIGAPPQFMDFRFTLHDRWHGEFHLDHCGALLDVDPMGDDYVVGMCHTIEDPTFDATAIATNPRAQVRPIHRPPRKPADRHPHCAWTVIIDESYPEAEGIPALDAVRETKAATWELDNVDASDDGLVDYSGPLVSDLDFGAFSHSALVRMADEVCLQMHLLNLSFAIAVRKRAKADAQLAISVNTRQLIGVAGLGAERIHRAMALPGGIEGALGVLELHPLLNPAGYVLAETSPDRLVVHNSPAHADGAWISLCTPASVQPLQAIATAVDPHLKVRISGTDTDWTAELIEADAPASELPEVLVAKVSRGSVFQFEPRRSLPLTVK
>NC_021251.1|WP_003900119.1|378950_380813_+|Hsp70-family-protein
MYDPLGLSIGTTNLVAAGNGGPPVTRRAVLTLYPHCAPKIGVPSQNPNLIEPGALMSGFVERIGDAVALVSPDGSVHDPDLLLVEALDAMVLTAGADASSSEIAIAVPAHWKPGAVHALRNGLRTHVGFVRSGMAPRLVSDAIAALTAVNSELGLPHGSVVGLLDFGGSATYVTLVETKSDSRTSDFQPVSATARYQDFSGSQIDQALLLRVIDQFGYGDDVDPASTAAVGQLGQLREQCRAAKERLSTDVATELFAELAGCSSSIEMTREQLEDLIQDPLTGFIYAFDDMLARHNASWADLAAVVTVGGGANIPLVTQRLSFHTRRPVLTASQPGCAAAMGALLLANRGGERDSRTRTSIGLATAAAAGTSVIELPAGDVMVIDHEALTDRELAWSQTDFPSEAPARFEGDSYNEGGPCWSMRLNAVEPPKGPAWRRIRVSQLLIGVSAVVAMTAIGGVALTLTAIERRPSPLPTPIVPGLAPMPPGSVVPSSRAPTPPPPPSTVAPLPSAAPAPTTVAPAPPPPTQVVTTTTAPPVTTTPRPSPTTTTTTAPPSTTTTTEPPVTTTSTIPTIPTTTTTVKMTTEWLHVPFLPVPIPVPIPQNPGAGEPQNPFGSLGSG
>NC_021251.1|WP_003401613.1|380884_381271_+|hypothetical-protein
MGDYGPFGFDPDEFDRVIREGSEGLRDAFERIGRFLSSSGAGTGWSAIFEDLSRRSRPAPETAGEAGDGVWAIYTVDADGGARVEQVYATELDALRANKDNTDPKRKVRFLPYGIAVSVLDDPVDEAQ
>NC_021251.1|WP_003401619.1|381273_381936_-|DUF3060-domain-containing-protein
MIVVWEHLCMNPEDDPEARIRELERPLADVARASELGGSQSGGYTYPPGPPPPPYSYGGPFGGPSPRSSSGNRAWWILAAVVVVGVLVLVGGIAAFSAQRLSQGNFVVLSPTPSVSRAVPTPTAQPATTLPPAGASLSVSGVNVNRTIACNDSIVSVSGMSNTVVITGHCTSLTVSGMRNSVTVDSVDTIEAAGFNNEVTYHSGSPKISNAGGSNSVQQG
>NC_021251.1|WP_003905279.1|381996_382881_+|family-16-glycosylhydrolase
MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAASAGPTPAPAAPAAATGGLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQYRDSRQNVFLDGNSNLVLRATREGNRYFGGLVHGLWRGGIGTTWEARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIEDLNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF

Crispr_ID: NC_021251_2

• CRISPR_ID: NC_021251_2
• CRISPR_location: 629677-629814
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_021251_2

Consensus_repeat	Method
CCGCCGACCACGCCGGTG	CRT

spacers of NC_021251_2

>2.1|629695|18|NC_021251|CRT
ACCACGTCGGCGACGACG
>2.2|629731|30|NC_021251|CRT
ACCACGCCGGTGACCACGCCGCCAACGACG
>2.3|629779|18|NC_021251|CRT
ACCACGCCGCCAACGACG

CRISPR arrays and Neighbor proteins around NC_021251_2

CRISPR arrays

The CRISPR arrays of NC_021251_2

>merge|NC_021251|2|629677-629814|CRT
CCGCCGACGACGCCGGTGACCACGTCGGCGACGACGCCGCCGACCACGCCGCCGACCACGCCGGTGACCACGCCGCCAACGACGCCGCCGACCACGCCGGTGACCACGCCGCCAACGACGCCGCCGACCACGCCGGTG

>NC_021251|2|1|629677-629814|CRT
CCGCCGACGACGCCGGTG	ACCACGTCGGCGACGACG
CCGCCGACCACGCCGCCG	ACCACGCCGGTGACCACGCCGCCAACGACG
CCGCCGACCACGCCGGTG	ACCACGCCGCCAACGACG
CCGCCGACCACGCCGGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003905331.1|618201_619176_+|c-type-cytochrome-biogenesis-protein-CcsB	unknown	unknown	gnl|CDD|274447
NC_021251.1|WP_003402901.1|634329_634608_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003402909.1|636426_637311_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235631
NC_021251.1|WP_003915439.1|637406_638309_-|1,4-dihydroxy-2-naphthoyl-CoA-synthase	unknown	unknown	gnl|CDD|181386
NC_021251.1|WP_003402861.1|622867_623875_-|beta-ketoacyl-ACP-synthase-III	unknown	unknown	gnl|CDD|273249
NC_021251.1|WP_003402886.1|630766_631429_+|DUF2064-domain-containing-protein	unknown	unknown	gnl|CDD|225763
NC_021251.1|WP_034166960.1|621103_622972_+|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_021251.1|WP_003402853.1|620639_620957_+|DUF4229-domain-containing-protein	unknown	unknown	gnl|CDD|379415
NC_021251.1|WP_003402904.1|634604_635858_-|inorganic-phosphate-transporter	unknown	unknown	gnl|CDD|223383
NC_021251.1|WP_003402890.1|631449_632799_-|integral-membrane-protein	unknown	unknown	unknown
NC_021251.1|WP_003402907.1|635977_636364_-|VOC-family-protein	unknown	unknown	gnl|CDD|319925
NC_021251.1|WP_003900954.1|626692_628126_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003402896.1|633967_634270_-|DUF3349-domain-containing-protein	unknown	unknown	gnl|CDD|371747
NC_021251.1|WP_003402875.1|630137_630770_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133022
NC_021251.1|WP_003910801.1|619217_620435_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|223531
NC_021251.1|WP_003901872.1|625642_626683_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187566
NC_021251.1|WP_003402851.1|620431_620593_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_071854203.1|632810_633953_-|o-succinylbenzoate--CoA-ligase	unknown	unknown	gnl|CDD|236108
NC_021251.1|WP_003402865.1|623956_624835_-|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	unknown	unknown	gnl|CDD|129834
NC_021251.1|WP_003402867.1|624851_625646_+|S-methyl-5'-thioadenosine-phosphorylase	unknown	unknown	gnl|CDD|236107

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003905331.1|618201_619176_+|c-type-cytochrome-biogenesis-protein-CcsB	gnl|CDD|274447	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB. Members of this protein family represent one of two essential proteins of system II for c-type cytochrome biogenesis. Additional proteins tend to be part of the system but can be replaced by chemical reductants such as dithiothreitol. This protein is designated CcsB in Bordetella pertussis and some other bacteria, resC in Bacillus (where there is additional N-terminal sequence), and CcsA in chloroplast. We use the CcsB designation here. Member sequences show regions of strong sequence conservation and variable-length, poorly conserved regions in between; sparsely filled columns were removed from the seed alignment prior to model construction. [Energy metabolism, Electron transport, Protein fate, Protein modification and repair].	1.52295e-96
NC_021251.1|WP_003402909.1|636426_637311_-|SDR-family-oxidoreductase	gnl|CDD|235631	PRK05866, PRK05866, SDR family oxidoreductase.	0
NC_021251.1|WP_003915439.1|637406_638309_-|1,4-dihydroxy-2-naphthoyl-CoA-synthase	gnl|CDD|181386	PRK08321, PRK08321, 1,4-dihydroxy-2-naphthoyl-CoA synthase.	0
NC_021251.1|WP_003402861.1|622867_623875_-|beta-ketoacyl-ACP-synthase-III	gnl|CDD|273249	TIGR00747, 3-oxoacyl-_synthase_3, 3-oxoacyl-(acyl-carrier-protein) synthase III. FabH in general initiate elongation in type II fatty acid synthase systems found in bacteria and plants. The two members of this subfamily from Bacillus subtilis differ from each other, and from FabH from E. coli, in acyl group specificity. Active site residues include Cys112, His244 and Asn274 of E. coli FabH. Cys-112 is the site of acyl group attachment. [Fatty acid and phospholipid metabolism, Biosynthesis].	1.342e-168
NC_021251.1|WP_003402886.1|630766_631429_+|DUF2064-domain-containing-protein	gnl|CDD|225763	COG3222, COG3222, Uncharacterized protein conserved in bacteria [Function unknown].	9.87249e-94
NC_021251.1|WP_034166960.1|621103_622972_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.05954e-29
NC_021251.1|WP_003402853.1|620639_620957_+|DUF4229-domain-containing-protein	gnl|CDD|379415	pfam14012, DUF4229, Protein of unknown function (DUF4229). This family of integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 95 and 122 amino acids in length.	3.3192e-13
NC_021251.1|WP_003402904.1|634604_635858_-|inorganic-phosphate-transporter	gnl|CDD|223383	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism].	1.51477e-96
NC_021251.1|WP_003402896.1|633967_634270_-|DUF3349-domain-containing-protein	gnl|CDD|371747	pfam11829, DUF3349, Protein of unknown function (DUF3349). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 99 to 124 amino acids in length.	2.96528e-44
NC_021251.1|WP_003402907.1|635977_636364_-|VOC-family-protein	gnl|CDD|319925	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	9.46222e-32
NC_021251.1|WP_003402875.1|630137_630770_+|glycosyltransferase-family-2-protein	gnl|CDD|133022	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.	8.28004e-38
NC_021251.1|WP_003910801.1|619217_620435_+|AAA-family-ATPase	gnl|CDD|223531	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility].	6.30316e-66
NC_021251.1|WP_003901872.1|625642_626683_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187566	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs. This subgroup contains UDP-N-acetylglucosamine 4-epimerase of Pseudomonas aeruginosa, WbpP, an extended SDR, that catalyzes the NAD+ dependent conversion of UDP-GlcNAc and UDPGalNA to UDP-Glc and UDP-Gal. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.57578e-70
NC_021251.1|WP_071854203.1|632810_633953_-|o-succinylbenzoate--CoA-ligase	gnl|CDD|236108	PRK07824, PRK07824, o-succinylbenzoate--CoA ligase.	0
NC_021251.1|WP_003402865.1|623956_624835_-|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	gnl|CDD|129834	TIGR00751, 14-dihydroxy-2-naphthoate_octaprenyltransferase, 1,4-dihydroxy-2-naphthoate octaprenyltransferase. This membrane-associated enzyme converts 1,4-dihydroxy-2-naphthoic acid (DHNA) to demethylmenaquinone, a step in menaquinone biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	5.02416e-126
NC_021251.1|WP_003402867.1|624851_625646_+|S-methyl-5'-thioadenosine-phosphorylase	gnl|CDD|236107	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase.	5.08819e-174

Protein sequences

>NC_021251.1|WP_003900954.1|626692_628126_-|hypothetical-protein
MGLSSDDTRRREVVRDLAAGALLIGALFFPWNLYFGFRIPDSSKTVFGLLLAVTSLSLASLAVTFAGRRSQLRLGLNVPYLLLVLAFVVFDAIQTIRLGGTVHVPGGVGPGGWLGITGALLSAQPALTGATTDEGSHSRWLRATQFLGYASMLGAALSTGFNLSWRVRYALEPAAGASGFGKQNLAVIDTAVVYGVVALAAVLVASRWLLRPTAAEALSTVALGGSTLIAGSIVWSLPIGREIDAFHGIAQNTSTAGVGYEGYLVWAAAAAMCAPLTLFRSPNAPPIDKAVWRAASRNGLLLIAVWCLGSVAMRLTDLVVAVLLNYPFSRYDSMALAAFDLATAVLAIWLRFNMATEALPARLISSLCGLLCTFTVSRVIVGVVLAPRFQASSGGSAHPVYGNDLAQQITSTFDVVLCGLALSILAAAIVIGRLRQLPQPPHTPALSRPAGSPRIFRSAGSTHPVRPKIYRPPDHSS
>NC_021251.1|WP_003901872.1|625642_626683_+|NAD-dependent-epimerase/dehydratase-family-protein
MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPLLAGVDLVCHQAAMVGAGINAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR
>NC_021251.1|WP_003402867.1|624851_625646_+|S-methyl-5'-thioadenosine-phosphorylase
MHNNGRMLGVIGGSGFYTFFGSDTRTVNSDTPYGQPSAPITIGTIGVHDVAFLPRHGAHHQYSAHAVPYRANMWALRALGVRRVFGPCAVGSLDPELEPGAVVVPDQLVDRTSGRADTYFDFGGVHAAFADPYCPTLRAAVTGLPGVVDGGTMVVIQGPRFSTRAESQWFAAAGCNLVNMTGYPEAVLARELELCYAAIALVTDVDAGVAAGDGVKAADVFAAFGENIELLKRLVRAAIDRVADERTCTHCQHHAGVPLPFELP
>NC_021251.1|WP_003402865.1|623956_624835_-|1,4-dihydroxy-2-naphthoate-polyprenyltransferase
MASFAQWVSGARPRTLPNAIAPVVAGTGAAAWLHAAVWWKALLALAVAVALVIGVNYANDYSDGIRGTDDDRVGPVRLVGSRLATPRSVLTAAMTSLALGALAGLVLALLSAPWLIAVGAICIAGAWLYTGGSKPYGYAGFGELAVFVFFGPVAVLGTQYTQALRVDWVGLAQAVATGALSCSVLVANNLRDIPTDARADKITLAVRLGDARTRMLYQGLLAVAGVLTFVLMLATPWCVVGLVAAPLALRAAGPVRSGRGGRELIPVLRDTGLAMLVWALAVAGALAFGQLS
>NC_021251.1|WP_003402861.1|622867_623875_-|beta-ketoacyl-ACP-synthase-III
MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDEWIYTRTGIKTRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPAAPMVAASLGAKGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLSPTIDMYDRGNCFIFADGAAAVVVGETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFVRLEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINELLVKNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGYGAGLSYAAQVVRMPKG
>NC_021251.1|WP_034166960.1|621103_622972_+|PE-family-protein
MSNLLVTPELVAAAAADLAGIGSAIGAANAAAGAPTMALLAAGADEVSAAVAAVFSSYAQQYQALSAAAAAFHDQFVRALAAGAGAYAGAEAANVEQQLLNAINAPTLALLGRPLIGNGADGAAGTGQAGGAGGLLYGNGGNGGSGAAGQAGGAGGAAGLIGHGGTGGVGGTGAAGGAGGTGGWLFGNGGAGGTGGAVTGVSTTGGPGGHGGDAGLYGFGGAGGAGGFGQSGAAGGAGGAGGAGGWLYGDGGDGGAGGNGGNESGTGVSGVGGVGGAGGAGGLLFGNGGVGGDGGDGSSTQDSGGDGGAGGAGGAGGWLLGNGGAGGAGGAASIKVATGGLGGDGGDAGLFGFGGDGGWGGRGVDARFGAAGGAAGAGGAGGWLYGDGGAGGVGGVGGAVFSLSSGDGGAGGAGGGGGWLFGNGGDGGAGGGGGGRFGSGSGAGGDGAVGGAGGAGAWFGNGGAGGVGGGGGRGTTAIGGDGGAGGAGGAGGWLYGDGGAGGAGGGGGRGGTGNDGGDGGDGGRGGDAQLLGNGGDGGAGGAGGPAGLALPPGPARPAGAAVPAVRCSAAPARPARTADPWLAPIFARSTLRHSHHLGGIAQTGAVADQQGQIAGLGRAGRQ
>NC_021251.1|WP_003402853.1|620639_620957_+|DUF4229-domain-containing-protein
MSEAPNDKTTRGVVDILVYATARLLLVVAVSAAIFGVARLIGLTEFPVVVATLFGLIIAMPLGIWVFSPLRRRATAALAVAGERRRAERERLRARLRGESLPEEQ
>NC_021251.1|WP_003402851.1|620431_620593_-|hypothetical-protein
MLYLLLVLILATLIYLGWRAARAQMNRPKTRVIGPDDDPEFLRRLGHGDNNRS
>NC_021251.1|WP_003910801.1|619217_620435_+|AAA-family-ATPase
MLVTEHPRTGVGAPDSGNGGTDHPTVQLPPVPSVGAPPAAAGGETPTRSVAGFRTQRLDPTAYGAYYSGPDEGPASPAERPPYRLEPVPHTPYPELATTTLLRPVKPPPSEGWRRLLYLLSGRLINAGEGPRAAHLNDLVAQVNRPLRGCYRIAVLSLKGGVGKTTITATLGATFADLRGDRVVAVDANPDRGTLSQKVPLETPATVRHLLRDADGIERYSDVRGYTSKGLSGLEVLASDSDPASSDAFSADDYTRTLDILERFYGLVLTDCGTGLLHSAMSAVLPRSDVLVVVSSGSIDGARSAAATLDWLQAHGHDDQVRNSIAVVNAVRPRAGKVDVGKVVEHFSRRCRAVRVVPFDPHLEEGAEIALDRLRRETREALTELAAVVAAGFPGDPRRCKPSFT
>NC_021251.1|WP_003905331.1|618201_619176_+|c-type-cytochrome-biogenesis-protein-CcsB
MNTLHVNVGLARYSDWAFTSAVVALVVALLLLAFEFAQVRGRGLAPLAVPAGSVATDSATPGIVADQRHRPFDERVGRGGLAVAYLGIGLLLACVVLRGLATQRVPWGNMYEFINLTCLSGLIAGAVVLRRARYRPLWVFLLVPVLILLTVSGRWLYANAAPVMPALQSYWLPIHVSVVSLGSGVFLVAGVASILFLVRTSRLGEPTGEGALAGMVRRLPDAQTLDGIAYRTTIFAFPVFGFGVMFGAIWAEEAWGRYWGWDPKETVSFVAWVVYAAYLHARSTAGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG
>NC_021251.1|WP_003402875.1|630137_630770_+|glycosyltransferase-family-2-protein
MLPCLNEEESLPAVLAAIPAGYRALVVDNNSTDDTATVAARHGAQVVVEPRPGYGSAVHAGVLAATTPIVAVIDADGSMDAGDLPKLVAELDKGADLVTGRRRPVAGLHWPWVARVGTVVMSWRLRTRHRLPVHDIAPMRVARREALLDLGVVDRRSGYPLELLVRAAAAGWRVVELDVSYGPRTGGKSKVSGSLRGSIIAILDFWKVIS
>NC_021251.1|WP_003402886.1|630766_631429_+|DUF2064-domain-containing-protein
MSCLPVSVLVVAKAPEPGRVKTRLAAAIGDKVAADIAAAALLDTLDAVAAAPVTARAVALTGDLDSAADSAEIRRRLKSFTVFRQRGDAFADRLANAHVDAADGYPVLQIGMDTPQVTAELLADCARLLLQIPAVLGLAFDGGWWVLGIRTPTAAECLRAVPMSQPDTGELTLKALRDNGIDVTLVQRLGDFDIVDDIALVRDCCAPGSRFAQATRAAGL
>NC_021251.1|WP_003402890.1|631449_632799_-|integral-membrane-protein
MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW
>NC_021251.1|WP_071854203.1|632810_633953_-|o-succinylbenzoate--CoA-ligase
MHVPAGSATALLLPALQRVLGGSDPALVAVPTQHESLLGALRVGEQIDDDVALVVTTSGTTGPPKGAMLTAAALTASASAAHDRLGGPGSWLLAVPPYHIAGLAVLVRSVIAGSVPVELNVSAGFDVTELPNAIKRLGSGRRYTSLVAAQLAKALTDPAATAALAELDAVLIGGGPAPRPILDAAAAAGITVVRTYGMSETSGGCVYDGVPLDGVRLRVLAGGRIAIGGATLAKGYRNPVSPDPFAEPGWFHTDDLGALESGDSGVLTVLGRADEAISTGGFTVLPQPVEAALGTHPAVRDCAVFGLADDRLGQRVVAAIVVGDGCPPPTLEALRAHVARTLDVTAAPRELHVVNVLPRRGIGKVDRAALVRRFAGEADQ
>NC_021251.1|WP_003402896.1|633967_634270_-|DUF3349-domain-containing-protein
MNRFLTSIVAWLRAGYPEGIPPTDSFAVLALLCRRLSHDEVKAVANELMRLGDFDQIDIGVVITHFTDELPSPEDVERVRARLAAQGWPLDDVRDREEHA
>NC_021251.1|WP_003402901.1|634329_634608_-|hypothetical-protein
MSAWFNYTATLKILIFSLLAGALLPGLFAVGVRLQAAGDGADATARRRPLLVAVSWAIFALVLAVVIIGVLYIARDFIAHHTGWAFLGATPK
>NC_021251.1|WP_003402904.1|634604_635858_-|inorganic-phosphate-transporter
MNLQLFLLLIVVVTALAFDFTNGFHDTGNAMATSIASGALAPRVAVALSAVLNLIGAFLSTAVAATIAKGLIDANLVTLELVFAGLVGGIVWNLLTWLLGIPSSSSHALIGGIVGATIAAVGLRGVIWSGVVSKVIVPAVVAALLATLVGAVGTWLVYRTTRGVAEKRTERGFRRGQIGSASLVSLAHGTNDAQKTMGVIFLALMSYGAVSTTASVPPLWVIVSCAVAMAAGTYLGGWRIIRTLGKGLVEIKPPQGMAAESSSAAVILLSAHFGYALSTTQVATGSVLGSGVGKPGAEVRWGVAGRMVVAWLVTLPLAGLVGAFTYGLVHFIGGYPGAILGFALLWLTATAIWLRSRRAPIDHTNVNADWEGNLTAGLEAGAQPLADQRPPVPAPPAPTPPPNHRAPQFGVTTRNAP
>NC_021251.1|WP_003402907.1|635977_636364_-|VOC-family-protein
MEILASRMLLRPADYQRSLSFYRDQIGLAIAREYGAGTVFFAGQSLLELAGYGEPDHSRGPFPGALWLQVRDLEATQTELVSRGVSIAREPRREPWGLHEMHVTDPDGITLIFVEVPEGHPLRTDTRA
>NC_021251.1|WP_003402909.1|636426_637311_-|SDR-family-oxidoreductase
MSKRPLRWLTEQITLAGMRPPISPQLLINRPAMQPVDLTGKRILLTGASSGIGAAATKQFGLHRAVVVAVARRKDLLDAVADRITGDGGTAMSLPCDLSDMEAIDALVEDVEKRIGGIDILINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRGLAPGMLERGDGHIINVATWGVLSEASPLFSVYNASKAALSAVSRIIETEWGSQGVHSTTLYYPLVATPMIAPTKAYDGLPALTAAEAAEWMVTAARTRPVRIAPRVAVAVNALDSIGPRWVNALMQRRNEQLNP
>NC_021251.1|WP_003915439.1|637406_638309_-|1,4-dihydroxy-2-naphthoyl-CoA-synthase
MSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF

Crispr_ID: NC_021251_3

• CRISPR_ID: NC_021251_3
• CRISPR_location: 690415-690491
• CRISPR_type: TypeV-U4
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021251_3

Consensus_repeat	Method
TGAGGTGCGGCGTGAGCGCGGGT	CRISPRCasFinder

spacers of NC_021251_3

>3.1|690438|31|NC_021251|CRISPRCasFinder
AGCGCGAACGGCAAGCCGAACCGTTGGACCC

CRISPR arrays and Neighbor proteins around NC_021251_3

CRISPR arrays

The CRISPR arrays of NC_021251_3

>merge|NC_021251|3|690415-690491|CRISPRCasFinder
TGAGGTGCGGCGTGAGCGCGGGTAGCGCGAACGGCAAGCCGAACCGTTGGACCCTGAGGTGCGGCGTGAGCGCGGGT

>NC_021251|3|2|690415-690491|CRISPRCasFinder
TGAGGTGCGGCGTGAGCGCGGGT	AGCGCGAACGGCAAGCCGAACCGTTGGACCC
TGAGGTGCGGCGTGAGCGCGGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003900181.1|687448_688894_+|virulence-factor-Mce-family-protein	unknown	unknown	gnl|CDD|273384
NC_021251.1|WP_003403148.1|697427_698189_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_021251.1|WP_003403128.1|694057_695293_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224292
NC_021251.1|WP_003403055.1|677617_680251_+|glycosidase	unknown	unknown	gnl|CDD|226067
NC_021251.1|WP_003403095.1|683517_684315_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223838
NC_021251.1|WP_003900973.1|696293_696800_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_021251.1|WP_003403107.1|686420_687452_+|MCE-family-protein	unknown	unknown	gnl|CDD|224380
NC_021251.1|WP_003403122.1|693228_693621_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350335
NC_021251.1|WP_003403164.1|698245_698557_+|hypothetical-protein	unknown	unknown	gnl|CDD|377032
NC_021251.1|WP_003905347.1|684316_685204_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223838
NC_021251.1|WP_003403139.1|695953_696190_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224913
NC_021251.1|WP_003403052.1|676777_677464_-|hypothetical-protein	unknown	unknown	gnl|CDD|378485
NC_021251.1|WP_003403144.1|696913_697384_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|236751
NC_021251.1|WP_003403125.1|693617_693875_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl|CDD|226603
NC_021251.1|WP_003403065.1|682798_683521_+|FadR-family-transcriptional-regulator-Mce2R	unknown	unknown	gnl|CDD|225097
NC_021251.1|WP_003905349.1|691626_693177_+|MCE-family-protein	unknown	unknown	gnl|CDD|224380
NC_021251.1|WP_003403137.1|695543_695957_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350248
NC_021251.1|WP_003403104.1|685209_686424_+|MCE-family-protein	unknown	unknown	gnl|CDD|378749
NC_021251.1|WP_003900178.1|680273_682661_-|flippase-like-domain-containing-protein	unknown	unknown	gnl|CDD|377103
NC_021251.1|WP_003403047.1|676310_676718_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350263

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003900181.1|687448_688894_+|virulence-factor-Mce-family-protein	gnl|CDD|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	1.51384e-92
NC_021251.1|WP_003403148.1|697427_698189_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.00442e-84
NC_021251.1|WP_003403128.1|694057_695293_-|ATP-binding-protein	gnl|CDD|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	1.27416e-77
NC_021251.1|WP_003403055.1|677617_680251_+|glycosidase	gnl|CDD|226067	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism].	0
NC_021251.1|WP_003403095.1|683517_684315_+|ABC-transporter-permease	gnl|CDD|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	9.02403e-82
NC_021251.1|WP_003900973.1|696293_696800_-|sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.10494e-27
NC_021251.1|WP_003403107.1|686420_687452_+|MCE-family-protein	gnl|CDD|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	4.80905e-74
NC_021251.1|WP_003403122.1|693228_693621_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350335	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 toxin of the VapBC toxin/antitoxin (TA) system. This family belongs to the PIN_VapC4-5_FitB-like subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. M. tuberculosis VapC4 interacts with, and cleaves tRNA44Cys-GCA. M. tuberculosis VapC5 has endonucleolytic activity with RNA, this activity is low with dsRNA, and no activity has been demonstrated on dsDNA. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	5.73431e-57
NC_021251.1|WP_003403164.1|698245_698557_+|hypothetical-protein	gnl|CDD|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	0.00241752
NC_021251.1|WP_003905347.1|684316_685204_+|ABC-transporter-permease	gnl|CDD|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	2.44952e-83
NC_021251.1|WP_003403139.1|695953_696190_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|224913	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription].	1.50922e-07
NC_021251.1|WP_003403052.1|676777_677464_-|hypothetical-protein	gnl|CDD|378485	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN. This family is conserved in Mycobacteriaceae and is likely to be a lipoprotein.	5.50369e-72
NC_021251.1|WP_003403144.1|696913_697384_-|HAMP-domain-containing-protein	gnl|CDD|236751	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB.	1.39186e-13
NC_021251.1|WP_003403125.1|693617_693875_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl|CDD|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	2.38527e-16
NC_021251.1|WP_003403065.1|682798_683521_+|FadR-family-transcriptional-regulator-Mce2R	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	4.76819e-52
NC_021251.1|WP_003905349.1|691626_693177_+|MCE-family-protein	gnl|CDD|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	2.23163e-80
NC_021251.1|WP_003403137.1|695543_695957_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350248	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins. This subfamily includes Mycobacterium tuberculosis VapC27 and VapC40. It belongs to the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	9.76945e-42
NC_021251.1|WP_003403104.1|685209_686424_+|MCE-family-protein	gnl|CDD|378749	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative. Mce4_CUP1 is a family of putative Mce4 transporters of cholesterol. The domain is found associated with pfam02470. The full TCDB classification for this family in conjunction with PF02470 is TC:3.A.1.27.4.	1.49168e-114
NC_021251.1|WP_003900178.1|680273_682661_-|flippase-like-domain-containing-protein	gnl|CDD|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	2.17737e-22
NC_021251.1|WP_003403047.1|676310_676718_+|PIN-domain-containing-protein	gnl|CDD|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.4948e-60

Protein sequences

>NC_021251.1|WP_003900181.1|687448_688894_+|virulence-factor-Mce-family-protein
MRTLTEFNRGRVGMMGAVVTVLVVGVAQSFTSVPMLFATPTYYAQFADTGGINTGDKVEIAGVNVGLVRSLAIRGNRVLIGFSLPGKTIGMQSRAAIRTDTILGRKNLEIEPRGSEPLKPNGFLPLAQTTTPYQIYDAFVDVTKAATGWDIDAVKRSLNVLSETFDQTAPHLSAALEGVKAFSDTVGRRGEQIEQLLANANRIARVLGDRSEQVNGLLVNAKTLLAAFKQRSQALRILLTNVSEASAQVSGLITDNPNLNHVLAQLRTVSEELVKRKNELADVAVLLGRYTAALTEAVGSGPFFKAMVVNLLPYQILQPWVDAAFKKRGIDPENFWRSAGLPEFRWPDPNGTRFPNGAPPAAPPVREGTPKHPGPAVPPGTPCSYTPAAGALPRPDTPLPCAGATVGPFGGPDFPAPLDVQPSPPNPDGPPPTPGILSAGRPGEPAPAVPGIPMPLPPNAPPGARTQPLEPFPDGTGGSNQ
>NC_021251.1|WP_003403107.1|686420_687452_+|MCE-family-protein
MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHTTGYSAVFTHVSGLRAGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATTASIRYLNLIGDRYLELGRGHSGQRLAPGATIPLEHTHPALDLDALLGGFRPLFQTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRDHAIGEVVNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAAHISSAAGTLADLLGADRPLLHSSFGHLEGIQQPLIDELAELDHVLGKLPDAYRIIGRAGGIYGDFFNFYLCDISLKVNGLQPGGPVRTVKLFGQPTGRCTPQ
>NC_021251.1|WP_003403104.1|685209_686424_+|MCE-family-protein
MPTLVTRKNRRAWLYVEGVVLLLVGALVLVLVYKQFRGEFTPKTELTMVASRAGLVMEAGSKVTYNGVEIGRVGSISEIERDGRPAAKLVLDVNPRYISLIPVNVVADIEAATLFGNKYVALSAPKIPQQQRISSHDVIDVGSVTTEFNTLFETITSIAEKVDPIELNATLSAVAQALDGLGGKFGESIVNGNQILAQLNPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLTSQQRDLDAALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTYSPELFCMIRNFHDAAPKVADAVGGNGYSLAAAGTILGAPNPYVYPDNLPRVNAHGGPGGRPGCWQTITRELWPAPYLVMDTGASLAPYNHVELGQPMFTEYVWGRQYGENTINP
>NC_021251.1|WP_003905347.1|684316_685204_+|ABC-transporter-permease
MVESSTASAAAVLRARYPRTAASLDRYGGGTARRLERTGTFARFTRISVVQIGWALRRYRRETLRLVAEIGMGTGAMAVVGGTVAIIGFVTLSGGSLIAIQGFASLGNIGVETFTGFFAALANTRVAAPIVSGVALAATVGAGATAQLGAMRISEEIDALEVMGIKSISFLVSTRILGGLVVIMPLYALALDMAFTSGQVVTTVFYGQSNGTYEHYFRTFLRPEDVGWSVVEVVIIAVVVMITHCYYGYTASGGPVGVGQAVGRSMRFSLVSVVVVVLLAELALYGVDPNFNLTV
>NC_021251.1|WP_003403095.1|683517_684315_+|ABC-transporter-permease
MTTHAVIITYLRDQTQPAVDAIGGFYRTCVLTGKALVRRPFHWREAIEQGWFITSVSLLPTLAVSIPLTVLIIFTLNILLAEFGAADISGAGAALGAVTQLGPLTTVLVIAGAGATAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVVAATIVAALLNGAVITIGLVGGFVFSVFIQHVSAGAYVGTLTLVTGLPEVIISVVKSATFGLIAGLVGCYRGLTTKGGPKGVGTAVNETLVLCVIALFATNVVLTTIGVRFGTGH
>NC_021251.1|WP_003403065.1|682798_683521_+|FadR-family-transcriptional-regulator-Mce2R
MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLDLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDSLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAALTTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANTSLMAVLVSQASRQ
>NC_021251.1|WP_003900178.1|680273_682661_-|flippase-like-domain-containing-protein
MRVDGRDIGVSGNLLQPLTRRTNDIIRAVLAAIYLVAVITSSLITRPQWVALEKSISEIVGVLSPSQSDLVYLGYGLAILALPFVILIGLIVSRQWKLLGAYAAAGLMAVLPLSISSSRIAAPRWHFDLSDRLATLLAQFLDDPRWIAMLAAVLTVSGPWLPARWRHWWWALLLAFVPIHLVVSAIVPARSLLGLAVGWLVGALVVLVVGTPALEVPLDGAIRALAKRGFAVSGLAVVRPAGPGPLVLSAACEQPNAGACSEALIELYGPHQSGGGALRQLWLKLTLRGTETAPLQASMRRAVEHRALMAIAFGDLGMANTTVIAVSPLDRGWTLYAHRPARGIGISECTKTTPTAHVWEALRTLHDQQISHGDLCSAEITVDNGAVLFGGFGEAEYGATDAQLQSDLAQLLVTTSALYDAEAAVTAAIDTFGKQAILAASRRLTKSAVPKRIRESITDPNAVIASTRAEVMRQTGADQIKAETITRFSRGQLIQLVLIGALVYVAYPFISTVPTFFSQLRTANWWWALLGLAVSALTYVGAAAALWACADGLVGFWKLSIMQVANTFAATTTPAGVGGLALSTRFLQKGGLTAVRATAAVALQQSVQVIVHLVLLILFSALAGTSTDLSHFVPNATVLYLIAGVALGIVGTFLFVPKLRRWLATAVRPKLREVTNDLIALAREPKRLALIVLGCAGTTLGAALALWASIEAFGGGTTFVTVTVVTMVGGTLASAAPTPGGVGAVEAALIGGLAAFGVPAALGVPSVLLYRLLTCWLPVFAGWQVMHWLTRHEMI
>NC_021251.1|WP_003403055.1|677617_680251_+|glycosidase
MRARRLRRALAALLAVAGLFVPFIVGVPTAYDGEPVFVAIPVEHVNTLIGTGTGAAIVGEINNFPGASVPFGMVQYSPDTVDNYAGYDYDNPHSTGFSMTHASVGCPAFGDISMLPTTTPLGSQPWSAWEEIAHDDTEVGVPGYYTVRFPGTGVIAELTATTRTGVGRFRYPRNGWPALFHVRSGASLAGNYAATLQIEDNTTITGSATSGGFCGKKNLYTVYFAMKFSQPFSSYGTWDGYAVYPGSHSMNSSYSGGYVGFPAGSVLEVRTALSYVSVDGARANLDAEGGASFDDIRAATSSEWNAALSRIAVAGRGPGDVDTFYTCLYRSLLHPNTFNDVDGRYIGFDGVIHSVASGHTHYANFSDWDTYRSLAPLQGLLFPQRASDMIQSLVTDAEQSGAYPRWALANSATGMMSGDSVVPLIVNLYAFGARDFDLKSALHYMVNAATQGGVGLDGFLERPGIAAYLRLGYGPQTAEFRANGRIAGASVTLEWSVDDFAISRFADSLGDTATAAVFQNRSQYWQNLFNPTTGYISPRSAAGFFPDGPGFVAYPSGFGQDGYDEGNAEQYLWWVPHNVAGLVTALGGRTAVVKRLDRFTKKLNVGPNEPYLWAGNEPGFGVPWLYNYIGQPWKTQRTVDRVRGLFGPTPGGAPGNDDLGALSSWYVWAALGLYPSTPGTTILTVNTPLFDRAVIALPTGKSIQITAPGASGRNRLKYIDGLTIDRQPSNQTFLPESIVRTGGDLTFSLAGTPNKVWGTAASAAPPSFGAGSSAVTVNIARPIIGIVPGATGTVTVDAQRMIDGVDDYTVTPTSYVVGIAAEPLSGQFDDDGAVSASVAITVARSVPSGYYPIYVTTSAGDSARTLIVLVVVAEAVE
>NC_021251.1|WP_003403052.1|676777_677464_-|hypothetical-protein
MKHFTAAVATVALSLALAGCSFNIKTDSAPTTSPTTTSPTTSTTTTSATTSAQAAGPNYTIADYIRDNHIQETPVHHGDPGSPTIDLPVPDDWRLLPESSRAPYGGIVYTQPADPNDPPTIVAILSKLTGDIDPAKVLQFAPGELKNLPGFQGSGDGSAATLGGFSAWQLGGSYSKNGKLRTVAQKTVVIPSQGAVFVLQLNADALDDETMTLMDAANVIDEQTTITP
>NC_021251.1|WP_003403047.1|676310_676718_+|PIN-domain-containing-protein
MIIDTSALLAYFDAAEPDHAAVSECIDSSADALVVSPYVVAELDYLVATRVGVDAELAVLRELAGGAWELANCGAAEIEQAARIVTKYQDQRIGIADAANVVLADRYRTRTILTLDRRHFSALRPIGGGRFTVIP
>NC_021251.1|WP_003905349.1|691626_693177_+|MCE-family-protein
MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIPSLVGIGRYTLYAELPRSGGLYRTANVTYRGITIGKVTGVEPTERGARATMSIDNGYQIPTDASANVHSVSAVGEQFVDLVSTRTSGPYLRHGQTITTTTVPSQIGPALDAANRGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAIAHDVRGSLEDIDDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTDPAVRSILANAAPTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVEQALVFLPQSGAIAQSVTTEFPGQAGLGVGGLALNQPPPCLTGFLPASEWRSPADTSTAPLPKGTYCRIPMDASNVVRGARNNPCVDVPGKRAATPRECRSNEAYVPGGTNPWYGDPNQMLSCPAPAARCDQPVKPGQVIPAPSVNNGISPLPADQLPGTPPPVNDPLQRPGSGTVQCNGQQPNPCVYTPSTFPTTIYDVQSGKVVAPDGVVYSVEASTHAGADGWKVMLAPTG
>NC_021251.1|WP_003403122.1|693228_693621_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MNVRRALADTSVFIGIEATRFDPDRFAGYEWGVSVVTLGELRLGVLQASGPEAAARRLSTYQLAQRFEPLGIDEAVSEAWALLVSKLRAAKLRVPINDSWIAATAVAHGIAILTQDNDYAAMPDVEVITI
>NC_021251.1|WP_003403125.1|693617_693875_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MSATIPARDLRNHTAEVLRRVAAGEEIEVLKDNRPVARIVPLKRRRQWLPAAEVIGELVRLGPDTTNLGEELRETLTQTTDDVRW
>NC_021251.1|WP_003403128.1|694057_695293_-|ATP-binding-protein
MGVVERAIAPSVLAALADTPVVVVNGARQVGKTTLVARLDYPGSSEVVSLDDVANRDAARDDPRAFVSRPVDTLVIDEAQLEPGLFRAIKAEVDRDRRPGRFLLTGSARLLSAPDMADALVGRVEIIELWPFSQGERAGIADGFVDALFTAPRELIHGSDMRRADLVDRIATGGFPDIVARSPSRRRAWFDNYLTTATQSVIREISPIERLAEMPRVLRLCAARTGAELNVSALANDLSIPARTTAGYLALLEAAFLIHRVPAWSTNLSRKVIRRPKLVVSDSGLACHLLGVTGATLDRPGRPLGPLLETFVANEIRKQLTWSTERPSLWHFRDRGGAEVDLVLEHPDGRVCGIEVKATSTPRAEDLRGLRYLAERLDDRFQFGVLLTAAPEATPFGPTLAALPVSTLWAG
>NC_021251.1|WP_003403137.1|695543_695957_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MKPPLAVDTSVAIPLLVRTHTAHAAVVAWWAHREAALCGHALAETYSVLTRLPRDLRLAPMDAARLLTERFAAPLLLSSRTTEHLPRVLAQFEITGGAVYDALVALAAAEHRAELATRDARAKDTYEKIGVHVVVAA
>NC_021251.1|WP_003403139.1|695953_696190_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MKAVVDAAGRIVVPKPLREALGLQPGSTVEISRYGAGLHLIPTGRTARLEEENGVLVATGETTIDDEVVFGLIDSGRK
>NC_021251.1|WP_003900973.1|696293_696800_-|sensor-histidine-kinase
MPITPLLHESVARFAATGADITTRAEPDLFVSIDPDHLRRILTAVLDNAITHGDGEIAVTAHARDGAVDIGVRDHGPGFADHFLPVAFDRFTRADTARGGRGSGLGLAIVAALTTTHGGHANATNHPDGGAELRITLPTPRPPFHEELPRITSSDTKDPNREHDTSDQ
>NC_021251.1|WP_003403144.1|696913_697384_-|HAMP-domain-containing-protein
MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPDPPTS
>NC_021251.1|WP_003403148.1|697427_698189_-|response-regulator-transcription-factor
MADETTMRAGRGPGRACGRVSGVRILVVEDEPKMTALLARALTEEGHTVDTVADGRHAVAAVDGGDYDAVVLDVMLPGIDGFEVCARLRRQRVWTPVLMLTARGAVTDRIAGLDGGADDYLTKPFNLDELFARLRALSRRGPIPRPPTLEAGDLRLDPSEHRVWRADTEIRLSHKEFTLLEALIRRPGIVHTRAQLLERCWDAAYEARSNIVDVYIRYLRDKIDRPFGVTSLETIRGAGYRLRKDGGRHALPR
>NC_021251.1|WP_003403164.1|698245_698557_+|hypothetical-protein
MNRIVQFGVSAVAAAAIGIGAGSGIAAAFDGEDEVTGPDADRARAAAVQAVPGGTAGEVETETGEGAAAYGVLVTRPDGTRVEVHLDRDFRVLDTEPADGDGG

Crispr_ID: NC_021251_4

• CRISPR_ID: NC_021251_4
• CRISPR_location: 1573757-1574829
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 15 spacers

Consensus repeat of NC_021251_4

Consensus_repeat	Method
CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	CRISPRCasFinder

spacers of NC_021251_4

>4.1|1573789|28|NC_021251|CRISPRCasFinder
GTTGCCGGGGGTGCCATCGTTGCCGGCC
>4.2|1573849|22|NC_021251|CRISPRCasFinder
GTTGCCGATTAGGACGGCGGCC
>4.3|1573903|22|NC_021251|CRISPRCasFinder
GGTACCGTCCTCGCCGGCGGTG
>4.4|1573957|22|NC_021251|CRISPRCasFinder
GTCGCCGATCAGGCCGGCGGCA
>4.5|1574011|25|NC_021251|CRISPRCasFinder
CTTGCCGAACACGCCGAAGCCGTCG
>4.6|1574068|76|NC_021251|CRISPRCasFinder
GGTGCCGTAGAGTTGTCCGCCGTTGCCACCGGCCCCGCCGGCACCACCAATTCCGCCATTGCCGTCGGGCCCCTGG
>4.7|1574176|22|NC_021251|CRISPRCasFinder
GTGGCCAATCAGACCGGCGGAC
>4.8|1574230|55|NC_021251|CRISPRCasFinder
CGGACTGGTGACGGTCCCGCCTGCCCCCCCGGTGCCGCCGTTGCCAATGAGTTGC
>4.9|1574317|55|NC_021251|CRISPRCasFinder
GCCCTGGCCACGGATATCACCGCCGTTGCCGCCGGCACCGCCGTCGCCGATCAGC
>4.10|1574404|31|NC_021251|CRISPRCasFinder
AATTGCGCCTTGCCCGCCGTTGCCGCCGGCA
>4.11|1574467|58|NC_021251|CRISPRCasFinder
GGCACCGCCCGCGCCCCCGAAGTTATTCTCCCCGACTTTGCCTCCAACCCCAGTTTGC
>4.12|1574557|64|NC_021251|CRISPRCasFinder
CAGGCCGCGGCCGTCGCCGCCGGTGCCGCCGGCCCCGCCGTTGCCTCCTGAGCTGACGCCGGTT
>4.13|1574653|34|NC_021251|CRISPRCasFinder
GTCGCCGTGCAGCCAGCCACCACCGCCACCGGCG
>4.14|1574719|25|NC_021251|CRISPRCasFinder
CTTGCCGCCACCGACCCCCCCTTGC
>4.15|1574776|22|NC_021251|CRISPRCasFinder
CAATCCGGCGGCGCCGCCGGCA

CRISPR arrays and Neighbor proteins around NC_021251_4

CRISPR arrays

The CRISPR arrays of NC_021251_4

>merge|NC_021251|4|1573757-1574829|CRISPRCasFinder
CCCCCGGTCCCGCCGACGCCGCCGCCCCCGCCGTTGCCGGGGGTGCCATCGTTGCCGGCCCCACCGTTTCCGCCGGCGCCGCCGCCCCCGCCGTTGCCGATTAGGACGGCGGCCCCACCGTTTCCGCCGGTCCCGCCGTTGCCGCCGGTACCGTCCTCGCCGGCGGTGCCGCCCTTTCCGCCGGTCCCGCCGGTCCCGGCGTCGCCGATCAGGCCGGCGGCACCGCCTCGCCCGCCGGTCCCGCCGGCGCCGCCCTTGCCGAACACGCCGAAGCCGTCGCCGCCCTTGCCGCCGGTGCCGCCGGTGCCGCCGGTGCCGTAGAGTTGTCCGCCGTTGCCACCGGCCCCGCCGGCACCACCAATTCCGCCATTGCCGTCGGGCCCCTGGGCGCTGTGCCCGCCGGCCCCGCCGGTGCCGCCGTGGCCAATCAGACCGGCGGACCCGCCGGCTCCGCCAGCACCGCCAAGACCGTTCGGACTGGTGACGGTCCCGCCTGCCCCCCCGGTGCCGCCGTTGCCAATGAGTTGCCCACCAGCGCCGCCGGCTCCACCGGCGCCGCCGCCCTGGCCACGGATATCACCGCCGTTGCCGCCGGCACCGCCGTCGCCGATCAGCCAGGCATTGCCACCGGCCCCGCCGGCGCCGCTAATTGCGCCTTGCCCGCCGTTGCCGCCGGCACCGCCGTTGCCGATGAGCCCGCCGGTACCGCCGGCACCGCCCGCGCCCCCGAAGTTATTCTCCCCGACTTTGCCTCCAACCCCAGTTTGCCCGCCGCGCCCGCCGGCCCCGCCGCTGCCCGACAGGCCGCGGCCGTCGCCGCCGGTGCCGCCGGCCCCGCCGTTGCCTCCTGAGCTGACGCCGGTTCCGCCCTGCCCGCCGTGTCCGCCGGCGCCGCCGTCGCCGTGCAGCCAGCCACCACCGCCACCGGCGCCGCCGATACCCCCCGTGCCGCCGTCGCCGGACTTGCCGCCACCGACCCCCCCTTGCCCGCCGGTGCCGCCGGACCCTCCGCTGCCCCACAATCCGGCGGCGCCGCCGGCACCGCCGGCACCGCCGACACCACCGGGGTCGCC

>NC_021251|4|3|1573757-1574829|CRISPRCasFinder
CCCCCGGTCCCGCCGACGCCGCCGCCCCCGCC	GTTGCCGGGGGTGCCATCGTTGCCGGCC
CCACCGTTTCCGCCGGCGCCGCCGCCCCCGCC	GTTGCCGATTAGGACGGCGGCC
CCACCGTTTCCGCCGGTCCCGCCGTTGCCGCC	GGTACCGTCCTCGCCGGCGGTG
CCGCCCTTTCCGCCGGTCCCGCCGGTCCCGGC	GTCGCCGATCAGGCCGGCGGCA
CCGCCTCGCCCGCCGGTCCCGCCGGCGCCGCC	CTTGCCGAACACGCCGAAGCCGTCG
CCGCCCTTGCCGCCGGTGCCGCCGGTGCCGCC	GGTGCCGTAGAGTTGTCCGCCGTTGCCACCGGCCCCGCCGGCACCACCAATTCCGCCATTGCCGTCGGGCCCCTGG
GCGCTGTGCCCGCCGGCCCCGCCGGTGCCGCC	GTGGCCAATCAGACCGGCGGAC
CCGCCGGCTCCGCCAGCACCGCCAAGACCGTT	CGGACTGGTGACGGTCCCGCCTGCCCCCCCGGTGCCGCCGTTGCCAATGAGTTGC
CCACCAGCGCCGCCGGCTCCACCGGCGCCGCC	GCCCTGGCCACGGATATCACCGCCGTTGCCGCCGGCACCGCCGTCGCCGATCAGC
CAGGCATTGCCACCGGCCCCGCCGGCGCCGCT	AATTGCGCCTTGCCCGCCGTTGCCGCCGGCA
CCGCCGTTGCCGATGAGCCCGCCGGTACCGCC	GGCACCGCCCGCGCCCCCGAAGTTATTCTCCCCGACTTTGCCTCCAACCCCAGTTTGC
CCGCCGCGCCCGCCGGCCCCGCCGCTGCCCGA	CAGGCCGCGGCCGTCGCCGCCGGTGCCGCCGGCCCCGCCGTTGCCTCCTGAGCTGACGCCGGTT
CCGCCCTGCCCGCCGTGTCCGCCGGCGCCGCC	GTCGCCGTGCAGCCAGCCACCACCGCCACCGGCG
CCGCCGATACCCCCCGTGCCGCCGTCGCCGGA	CTTGCCGCCACCGACCCCCCCTTGC
CCGCCGGTGCCGCCGGACCCTCCGCTGCCCCA	CAATCCGGCGGCGCCGCCGGCA
CCGCCGGCACCGCCGACACCACCGGGGTCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003898859.1|1567012_1568269_+|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC	unknown	unknown	gnl|CDD|235513
NC_021251.1|WP_003407295.1|1582162_1582645_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_021251.1|WP_003407264.1|1572618_1573653_+|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197666
NC_021251.1|WP_003407272.1|1576081_1576339_-|CopG-family-transcriptional-regulator	unknown	unknown	gnl|CDD|279710
NC_021251.1|WP_003900331.1|1565972_1566599_+|guanylate-kinase	unknown	unknown	gnl|CDD|234719
NC_021251.1|WP_003905549.1|1563340_1564960_+|PPE-family-protein	unknown	unknown	gnl|CDD|227938
NC_021251.1|WP_003407260.1|1571155_1572541_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NC_021251.1|WP_003407282.1|1578501_1579104_+|lysoplasmalogenase	unknown	unknown	gnl|CDD|226237
NC_021251.1|WP_003905554.1|1577405_1578368_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|369561
NC_021251.1|WP_003900336.1|1583737_1584676_+|methionyl-tRNA-formyltransferase	unknown	unknown	gnl|CDD|234567
NC_021251.1|WP_003407240.1|1565520_1565838_+|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003407276.1|1576421_1577381_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|369561
NC_021251.1|WP_003407257.1|1569680_1571159_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224983
NC_021251.1|WP_003900333.1|1568396_1569608_+|methionine-adenosyltransferase	unknown	unknown	gnl|CDD|235374
NC_021251.1|WP_003407292.1|1581169_1581994_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_021251.1|WP_003407285.1|1579184_1581152_+|primosomal-protein-N'	unknown	unknown	gnl|CDD|237844
NC_021251.1|WP_003898861.1|1575683_1576085_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350308
NC_021251.1|WP_003407248.1|1566664_1566997_+|DNA-directed-RNA-polymerase-subunit-omega	unknown	unknown	gnl|CDD|188073
NC_021251.1|WP_014585171.1|1582716_1583541_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_021251.1|WP_003407225.1|1563035_1563344_+|PE-family-protein	unknown	unknown	gnl|CDD|376422

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003898859.1|1567012_1568269_+|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC	gnl|CDD|235513	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated.	0
NC_021251.1|WP_003407295.1|1582162_1582645_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.03006e-24
NC_021251.1|WP_003407264.1|1572618_1573653_+|AraC-family-transcriptional-regulator	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.2925e-21
NC_021251.1|WP_003407272.1|1576081_1576339_-|CopG-family-transcriptional-regulator	gnl|CDD|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	7.93081e-06
NC_021251.1|WP_003900331.1|1565972_1566599_+|guanylate-kinase	gnl|CDD|234719	PRK00300, gmk, guanylate kinase; Provisional.	8.01602e-101
NC_021251.1|WP_003905549.1|1563340_1564960_+|PPE-family-protein	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	2.39081e-75
NC_021251.1|WP_003407260.1|1571155_1572541_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	3.46688e-73
NC_021251.1|WP_003407282.1|1578501_1579104_+|lysoplasmalogenase	gnl|CDD|226237	COG3714, COG3714, Predicted membrane protein [Function unknown].	2.43759e-45
NC_021251.1|WP_003905554.1|1577405_1578368_-|alpha/beta-hydrolase	gnl|CDD|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	5.61732e-87
NC_021251.1|WP_003900336.1|1583737_1584676_+|methionyl-tRNA-formyltransferase	gnl|CDD|234567	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed.	5.56225e-154
NC_021251.1|WP_003407276.1|1576421_1577381_-|alpha/beta-hydrolase	gnl|CDD|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	7.78908e-92
NC_021251.1|WP_003407257.1|1569680_1571159_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	7.312e-122
NC_021251.1|WP_003900333.1|1568396_1569608_+|methionine-adenosyltransferase	gnl|CDD|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NC_021251.1|WP_003407292.1|1581169_1581994_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.4474e-23
NC_021251.1|WP_003407285.1|1579184_1581152_+|primosomal-protein-N'	gnl|CDD|237844	PRK14873, PRK14873, primosomal protein N'.	0
NC_021251.1|WP_003898861.1|1575683_1576085_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350308	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.0663e-47
NC_021251.1|WP_003407248.1|1566664_1566997_+|DNA-directed-RNA-polymerase-subunit-omega	gnl|CDD|188073	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit. This small component of highly purified E. coli RNA polymerase is not required for transcription, but acts in assembly and is present in stochiometric amounts. The trusted cutoff excludes archaeal homologs but captures some organellar sequences. [Transcription, DNA-dependent RNA polymerase].	1.81185e-20
NC_021251.1|WP_014585171.1|1582716_1583541_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.66024e-22
NC_021251.1|WP_003407225.1|1563035_1563344_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	6.65327e-12

Protein sequences

>NC_021251.1|WP_003407264.1|1572618_1573653_+|AraC-family-transcriptional-regulator
MGHLPPPAEVRHPVYATRVLCEVANERGVPTADVLAGTAIEPADLDDPDAVVGALDEITAVRRLLARLPDDAGIGIDVGSRFALTHFGLFGFAVMSCGTLRELLTIAMRYFALTTMHVDITLFETADDCLVELDASHLPADVRGFFIERDIAGIIATTTSFALPLAAKYADQVSAELAVDAELLRPLLELVPVHDVAFGRAHNRVHFPRAMFDEPLPQADRHTLEMCIAQCDVLMQRNERRRGITALVRSKLFRDSGLFPTFTDVAGELDMHPRTLRRRLAEEGTSFRALLGEARSTVAVDLLRNVGLTVQQVSTRLGYTEVSTFSHAFKRWYGVAPSEYSRRG
>NC_021251.1|WP_003407260.1|1571155_1572541_-|cytochrome-P450
MATATTQRPLKGPAKRMSTWTMTREAITIGFDAGDGFLGRLRGSDITRFRCAGRRFVSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGLNLLTDEGDSWARHRGALNSTFARRHLRGLVGLMIDPIADVTAALVPGAQFDMHQSMVETTLRVVANALFSQDFGPLVQSMHDLATRGLRRAEKLERLGLWGLMPRTVYDTLIWCIYSGVHLPPPLREMQEITLTLDRAINSVIDRRLAEPTNSADLLNVLLSADGGIWPRQRVRDEALTFMLAGHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFSSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPRWWPDPDRFDPGRFLRCPTDRPRCAYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKHGVHVIGRRR
>NC_021251.1|WP_003407257.1|1569680_1571159_-|NAD(P)/FAD-dependent-oxidoreductase
MMPDYHALIVGAGFSGIGAAIKLDRAGFSDYLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHELKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGEITARFLISACGILTVPKLPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGIIGTGASAVQVIPEMAPIVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRIPGGKAVHRLLSQAFVEATFPIAAHYFAVFPLAKHMESAGRRYLRQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVATTDGASHEIDVLVLATGFKVLDTDSIPTYAVTGTGGASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHIIRCLKRARRTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGDVPLRPTTTVEAYWRSRRFDLGDYRISS
>NC_021251.1|WP_003900333.1|1568396_1569608_+|methionine-adenosyltransferase
MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI
>NC_021251.1|WP_003898859.1|1567012_1568269_+|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC
MVDHKRIPKQVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESALRFVGAATFEALSGEPVCTDVFADVPAVPHVHLGQQADLVVVAPATADLLARAAAGRADDLLTATLLTARCPVLFAPAMHTEMWLHPATVDNVATLRRRGAVVLEPATGRLTGADSGAGRLPEAEEITTLAQLLLERHDALPYDLAGRKLLVTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTLIAGHTAGLVDPAGVEVVHVSSAQQLADAVSKHAPTADVLVMAAAVADFRPAQVATAKIKKGVEGPPTIELLRNDDVLAGVVRARAHGQLPNMRAIVGFAAETGDANGDVLFHARAKLRRKGCDLLVVNAVGEGRAFEVDSNDGWLLASDGTESALQHGSKTLMASRIVDAIVTFLAGCSS
>NC_021251.1|WP_003407248.1|1566664_1566997_+|DNA-directed-RNA-polymerase-subunit-omega
MSISQSDASLAAVPAVDQFDPSSGASGGYDTPLGITNPPIDELLDRVSSKYALVIYAAKRARQINDYYNQLGEGILEYVGPLVEPGLQEKPLSIALREIHADLLEHTEGE
>NC_021251.1|WP_003900331.1|1565972_1566599_+|guanylate-kinase
MSVGEGPDTKPTARGQPAAVGRVVVLSGPSAVGKSTVVRCLRERIPNLHFSVSATTRAPRPGEVDGVDYHFIDPTRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPEAVTVFLAPPSWQDLQARLIGRGTETADVIQRRLDTARIELAAQGDFDKVVVNRRLESACAELVSLLVGTAPGSP
>NC_021251.1|WP_003407240.1|1565520_1565838_+|hypothetical-protein
MALPQLTDEQRAAALEKAAAARRARAELKDRLKRGGTNLTQVLKDAESDEVLGKMKVSALLEALPKVGKVKAQEIMTELEIAPTRRLRGLGDRQRKALLEKFGSA
>NC_021251.1|WP_003905549.1|1563340_1564960_+|PPE-family-protein
MTEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASDGWQGQAAEAFVAAYMPFLAWLIQASADCVEMAAQQHVVIEAYTAAVELMPTQVELAANQIKLAVLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVSRSALSAMPHTSPPPLILKSDELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYDDYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLGQYPQLLSAALTGVIAHLGAITGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVGPAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPYLVGGGGPGIGFGSGQSAHAKAAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGARASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR
>NC_021251.1|WP_003407225.1|1563035_1563344_+|PE-family-protein
MTLRVVPESLAGASAAIEAVTARLAAAHAAAAPFIAAVIPPGSDSVSVCNAVEFSVHGSQHVAMAAQGVEELGRSGVGVAESGASYAARDALAAASYLSGGL
>NC_021251.1|WP_003898861.1|1575683_1576085_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MILVDSDVLIAHLRGVVAARDWLVSARKDGPLAISVVSTAELIGGMRTAERREVWRLLASFRVQPATEVIARRAGDMMRRYRRSHNRIGLGDYLIAATADVQDLQLATLNVWHFPMFEQLKPPFAVPGHRPRA
>NC_021251.1|WP_003407272.1|1576081_1576339_-|CopG-family-transcriptional-regulator
MKRTNIYLDEEQTASLDKLAAQEGVSRAELIRLLLNRALTTAGDDLASDLQAINDSFGTLRHLDPPVRRSGGREQHLAQVWRATS
>NC_021251.1|WP_003407276.1|1576421_1577381_-|alpha/beta-hydrolase
MTEPTVARPDIDPVLKMLLDTFPVTFTAADGVEVARARLRQLKTPPELLPELRIEERTVGYDGLTDIPVRVYWPPVVRDNLPVVVYYHGGGWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAALRWVGENAAELGGDPSRIAVAGDSAGGNISAVMAQLARDVGGPPLVFQLLWYPTTMADLSLPSFTENADAPILDRDVIDAFLAWYVPGLDISDHTMLPTTLAPGNADLSGLPPAFIGTAEHDPLRDDGACYAELLTAAGVSVELSNEPTMVHGYVNFALVVPAAAEATGRGLAALKRALHA
>NC_021251.1|WP_003905554.1|1577405_1578368_-|alpha/beta-hydrolase
MPSLDNTADEKPAIDPILLKVLDAVPFRLSIDDGIEAVRQRLRDLPRQPVHPELRVVDLAIDGPAGPIGTRIYWPPTCPDQAEAPVVLYLHGGGFVMGDLDTHDGPCRQHAVGADAIVVSVDYRLAPEHPYPAAIEDAWAATRWVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARDMGGPPIVFQLLWYPSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNPPAPMAPGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVHNAQTLVHGYVGYAGVVPAATEATNRGLVALRVVLHG
>NC_021251.1|WP_003407282.1|1578501_1579104_+|lysoplasmalogenase
MLQPAFKASMAVLLAAAAVAHPIGRERRWLVPALLLSATGDWLLAIPWWTWAFVFGLGAFLLAHLCFIGALLPLARQAAPSRGRVAAVVAMCVASAGLLVWFWPHLGKDNLTIPVTVYIVALSAMVCTALLARLPTIWTAVGAVCFAASDSMIGIGRFILGNEALAVPIWWSYAAAEILITAGFFFGREVPDNAAAPTDS
>NC_021251.1|WP_003407285.1|1579184_1581152_+|primosomal-protein-N'
MLSVPHLDRDFDYLVPAEHSDDAQPGVRVRVRFHGRLVDGFVLERRSDSDHHGKLGWLDRVVSPEPVLTTEIRRLVDAVAARYAGTRQDVLRLAVPARHARVEREITTAPGRPVVAPVDPSGWAAYGRGRQFLAALADSRAARAVWQALPGELWADRFAEAAAQTVRAGRTVLAIVPDQRDLDTLWQAATALVDEHSVVALSAGLGPEARYRRWLAALRGSARLVIGTRSAVFAPLSELGLVMVWADADDSLAEPRAPYPHAREVAMLRAHQARCAALIGGYARTAEAHALVRSGWAHDVVAPRPEVRARSPRVVALDDSGYDDARDPAARTARLPSIALRAARSALQSGAPVLVQVPRRGYIPSLACGRCRAIARCRSCTGPLSLQGAGSPGAVCRWCGRVDPTLRCVRCGSDVVRAVVVGARRTAEELGRAFPGTAVITSAGDTLVPQLDAGPALVVATPGAEPRAPGGYGAALLLDSWALLGRQDLRAAEDALWRWMTAAALVRPRGAGGVVTVVAESSIPTVQSLIRWDPVGHAEAELAARTEVGLPPSVHIAALDGPAGTVTALLEAARLPDPDRLQADLLGPVDLPPGVRRPAGIPADAPVIRMLLRVCREQGLELAASLRRGIGVLSARQTRQTRSLVRVQIDPLHIG
>NC_021251.1|WP_003407292.1|1581169_1581994_-|class-I-SAM-dependent-methyltransferase
MTVYTPTSERQAPATTHRQMWALGDYAAIAEELLAPLGPILVSTSGIRRGDRVLDVAAGSGNVSIPAAMAGAHVTASDLTPELLRRAQARAAAAGLELGWREANAEALPFSAGEFDAVLSTIGVMFAPRHQRTADELARVCRRGGKISTLNWTPEGFYGKLLSTIRPYRPTLPAGAPHEVWWGSEDYVSGLFRDHVSDIRTRRGSLTVDRFGCPDECRDYFKNFYGPAINAYRSIADSPECVATLDAEITELCREYLCDGVMQWEYLIFTARKC
>NC_021251.1|WP_003407295.1|1582162_1582645_+|MarR-family-transcriptional-regulator
MMPTEYPATAEESVDVITDALLTASRLLVAISAHSIAQVDENITIPQFRTLVILSNHGPINLATLATLLGVQPSATGRMVDRLVGAELIDRLPHPTSRRELLAALTKRGRDVVRQVTEHRRTEIARIVEQMAPAERHGLVRALTAFTEAGGEPDARYEIE
>NC_021251.1|WP_014585171.1|1582716_1583541_-|class-I-SAM-dependent-methyltransferase
MTIDTSAREDQTLAATHRAMWALGDYALMAEEVMAPLGPILVAAAGIGPGVRVLDVAAGSGNISLPAAKTGATVISTDLTPELLQRSQARAAQQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQAAADELVRVCRPGGTIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSALWGREAYVTGLLGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIGDNAVLAAELDRQLVELAAQYLSDGVMEWEYLLLTAEKR
>NC_021251.1|WP_003900336.1|1583737_1584676_+|methionyl-tRNA-formyltransferase
MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPSPVAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLLAVPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGPIYGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPADGVSVAPKITVANARVRWDLPAAVVERRIRAVTPNPGAWTLIGDLRVKLGPVHLDAAHRPSKPLPPGGIHVERTSVWIGTGSEPVRLGQIQPPGKKLMNAADWARGARLDLAARAT

Crispr_ID: NC_021251_5

• CRISPR_ID: NC_021251_5
• CRISPR_location: 1858882-1859057
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_021251_5

Consensus_repeat	Method
GCCGCCGTTGCCGTACAA	PILER-CR

spacers of NC_021251_5

>5.1|1858900|66|NC_021251|PILER-CR
CAGTCCGCCGGTGCCGCCGGCCCCGCCAGCGCCGCCTGCACCTCCAGCACCGCCGGCGCCGCCGGC
>5.2|1858984|62|NC_021251|PILER-CR
ATCAATCCGGCGGCCCCGCCGTTACCGCCGGCCCCGCCGTCGGGTCCGCCGGCCCCGCCGTT

CRISPR arrays and Neighbor proteins around NC_021251_5

CRISPR arrays

The CRISPR arrays of NC_021251_5

>merge|NC_021251|5|1858882-1859057|PILER-CR
CCGCCGTTGCCATACAACAGTCCGCCGGTGCCGCCGGCCCCGCCAGCGCCGCCTGCACCTCCAGCACCGCCGGCGCCGCCGGCGCCGCCGTTGCCGATCAATCCGGCGGCCCCGCCGTTACCGCCGGCCCCGCCGTCGGGTCCGCCGGCCCCGCCGTTGCCGCCGTTGCCGTACAA

>NC_021251|5|1|1858882-1859057|PILER-CR
CCGCCGTTGCCATACAAC	AGTCCGCCGGTGCCGCCGGCCCCGCCAGCGCCGCCTGCACCTCCAGCACCGCCGGCGCCGCCGGCG
CCGCCGTTGCCGATCAAT	CCGGCGGCCCCGCCGTTACCGCCGGCCCCGCCGTCGGGTCCGCCGGCCCCGCCGTTGCCGCC
GTTGCCGTACAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003408163.1|1862820_1864023_+|acetylornithine-transaminase	unknown	unknown	gnl|CDD|235112
NC_021251.1|WP_003901219.1|1852810_1853836_+|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|234780
NC_021251.1|WP_003408141.1|1848476_1849532_-|DUF2236-domain-containing-protein	unknown	unknown	gnl|CDD|226188
NC_021251.1|WP_003408106.1|1847005_1847200_+|50S-ribosomal-protein-L35	unknown	unknown	gnl|CDD|234676
NC_021251.1|WP_003898960.1|1859673_1860732_+|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl|CDD|234761
NC_021251.1|WP_003901217.1|1846350_1846956_+|translation-initiation-factor-IF-3	unknown	unknown	gnl|CDD|234582
NC_021251.1|WP_003408145.1|1851808_1852615_+|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_016330404.1|1853835_1856331_+|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234804
NC_021251.1|WP_003408161.1|1861939_1862824_+|acetylglutamate-kinase	unknown	unknown	gnl|CDD|234869
NC_021251.1|WP_003902218.1|1869401_1875782_+|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|225858
NC_021251.1|WP_003408144.1|1850851_1851802_+|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NC_021251.1|WP_003408180.1|1866736_1868149_+|argininosuccinate-lyase	unknown	unknown	gnl|CDD|179143
NC_021251.1|WP_003408178.1|1864939_1865452_+|arginine-repressor	unknown	unknown	gnl|CDD|235116
NC_021251.1|WP_003408160.1|1860728_1861943_+|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	unknown	unknown	gnl|CDD|235441
NC_021251.1|WP_003408181.1|1868257_1869319_+|type-III-polyketide-synthase	unknown	unknown	gnl|CDD|225958
NC_021251.1|WP_003408112.1|1847683_1848466_+|RNA-methyltransferase	unknown	unknown	gnl|CDD|223640
NC_021251.1|WP_003900384.1|1849841_1850774_+|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_021251.1|WP_003408179.1|1865460_1866657_+|argininosuccinate-synthase	unknown	unknown	gnl|CDD|234785
NC_021251.1|WP_003408108.1|1847261_1847651_+|50S-ribosomal-protein-L20	unknown	unknown	gnl|CDD|179959
NC_021251.1|WP_003408165.1|1864019_1864943_+|ornithine-carbamoyltransferase	unknown	unknown	gnl|CDD|234835

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003408163.1|1862820_1864023_+|acetylornithine-transaminase	gnl|CDD|235112	PRK03244, argD, acetylornithine transaminase.	0
NC_021251.1|WP_003901219.1|1852810_1853836_+|phenylalanine--tRNA-ligase-subunit-alpha	gnl|CDD|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NC_021251.1|WP_003408141.1|1848476_1849532_-|DUF2236-domain-containing-protein	gnl|CDD|226188	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown].	9.74975e-121
NC_021251.1|WP_003408106.1|1847005_1847200_+|50S-ribosomal-protein-L35	gnl|CDD|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	6.28584e-22
NC_021251.1|WP_003898960.1|1859673_1860732_+|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl|CDD|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	2.79046e-163
NC_021251.1|WP_003901217.1|1846350_1846956_+|translation-initiation-factor-IF-3	gnl|CDD|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	1.85157e-96
NC_021251.1|WP_003408108.1|1847261_1847651_+|50S-ribosomal-protein-L20	gnl|CDD|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	4.30337e-59
NC_021251.1|WP_016330404.1|1853835_1856331_+|phenylalanine--tRNA-ligase-subunit-beta	gnl|CDD|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NC_021251.1|WP_003408161.1|1861939_1862824_+|acetylglutamate-kinase	gnl|CDD|234869	PRK00942, PRK00942, acetylglutamate kinase; Provisional.	3.05888e-144
NC_021251.1|WP_003902218.1|1869401_1875782_+|type-I-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NC_021251.1|WP_003408144.1|1850851_1851802_+|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	1.54804e-32
NC_021251.1|WP_003408180.1|1866736_1868149_+|argininosuccinate-lyase	gnl|CDD|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NC_021251.1|WP_003408178.1|1864939_1865452_+|arginine-repressor	gnl|CDD|235116	PRK03341, PRK03341, arginine repressor; Provisional.	2.2334e-85
NC_021251.1|WP_003408160.1|1860728_1861943_+|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	gnl|CDD|235441	PRK05388, argJ, bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ.	0
NC_021251.1|WP_003408181.1|1868257_1869319_+|type-III-polyketide-synthase	gnl|CDD|225958	COG3424, BcsA, Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport, and catabolism].	0
NC_021251.1|WP_003408112.1|1847683_1848466_+|RNA-methyltransferase	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	5.81541e-71
NC_021251.1|WP_003900384.1|1849841_1850774_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	4.70102e-25
NC_021251.1|WP_003408179.1|1865460_1866657_+|argininosuccinate-synthase	gnl|CDD|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NC_021251.1|WP_003408165.1|1864019_1864943_+|ornithine-carbamoyltransferase	gnl|CDD|234835	PRK00779, PRK00779, ornithine carbamoyltransferase; Provisional.	0

Protein sequences

>NC_021251.1|WP_016330404.1|1853835_1856331_+|phenylalanine--tRNA-ligase-subunit-beta
MRLPYSWLREVVAVGASGWDVTPGELEQTLLRIGHEVEEVIPLGPVDGPVTVGRVADIEELTGYKKPIRACAVDIGDRQYREIICGATNFAVGDLVVVALPGATLPGGFTISARKAYGRNSDGMICSAAELNLGADHSGILVLPPGAAEPGADGAGVLGLDDVVFHLAITPDRGYCMSVRGLARELACAYDLDFVDPASNSRVPPLPIEGPAWPLTVQSETGVRRFALRPVIGIDPAAVSPWWLQRRLLLCGIRATCPAVDVTNYVMLELGHPMHAHDRNRISGTLGVRFARSGETAVTLDGIERKLDTADVLIVDDAATAAIGGVMGAASTEVRADSTDVLLEAAIWDPAAVSRTQRRLHLPSEAARRYERTVDPAISVAALDRCARLLADIAGGEVSPTLTDWRGDPPCDDWSPPPIRMGVDVPDRIAGVAYPQGTTARRLAQIGAVVTHDGDTLTVTPPSWRPDLRQPADLVEEVLRLEGLEVIPSVLPPAPAGRGLTAGQQRRRTIGRSLALSGYVEILPTPFLPAGVFDLWGLEADDSRRMTTRVLNPLEADRPQLATTLLPALLEALVRNVSRGLVDVALFAIAQVVQPTEQTRGVGLIPVDRRPTDDEIAMLDASLPRQPQHVAAVLAGLREPRGPWGPGRPVEAADAFEAVRIIARASRVDVTLRPAQYLPWHPGRCAQVFVGESSVGHAGQLHPAVIERSGLPKGTCAVELNLDAIPCSAPLPAPRVSPYPAVFQDVSLVVAADIPAQAVADAVRAGAGDLLEDIALFDVFTGPQIGEHRKSLTFALRFRAPDRTLTEDDASAARDAAVQSAAERVGAVLRG
>NC_021251.1|WP_003901219.1|1852810_1853836_+|phenylalanine--tRNA-ligase-subunit-alpha
MLSPEALTTAVDAAQQAIALADTLDVLARVKTEHLGDRSPLALARQALAVLPKEQRAEAGKRVNAARNAAQRSYDERLATLRAERDAAVLVAEGIDVTLPSTRVPAGARHPIIMLAEHVADTFIAMGWELAEGPEVETEQFNFDALNFPADHPARGEQDTFYIAPEDSRQLLRTHTSPVQIRTLLARELPVYIISIGRTFRTDELDATHTPIFHQVEGLAVDRGLSMAHLRGTLDAFARAEFGPSARTRIRPHFFPFTEPSAEVDVWFANKIGGADWVEWGGCGMVHPNVLRATGIDPDLYSGFAFGMGLERTLQFRNGIPDMRDMVEGDVRFSLPFGVGA
>NC_021251.1|WP_003408145.1|1851808_1852615_+|hypothetical-protein
MIYRVACLLARIRFTVGYVAALASVSTTILMHGPQVHAQVIRHASTNLHNLAHGHLGTLWNSAFVIDEGPLYFWLPCLACLLAVAELQLRSLRLTVAFVVGHIGATLLVAAVLAGAIEIGWLPWSISRVSDVGMSYGALAALGALTAAIPGRWRPAWIGWWVSLGLATATIGGGFTDAGHTVALLLGMLVTACFTRPARWTLGRCALLAVASGFCLVLLAHSWWSLVSGSALGLLGALGAAGFARWTRARATSLPPGALAIPQPALSR
>NC_021251.1|WP_003408144.1|1850851_1851802_+|adenylate/guanylate-cyclase-domain-containing-protein
MPGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFDEMSPDAQ
>NC_021251.1|WP_003900384.1|1849841_1850774_+|PE-family-protein
MSFLTVAPDMVTAAAGNLESVGSALNEAAAAAAPATVGLAAPAADRVSAVVAAMLGAYARDFQGISAQIAGFHNQFVGALRGGAAAYASAEAANVQQTVVNAVNAPAQALLGHPLIGPETVGSSAAAVSFGFGPLLLAGSDPLLAVPFSYPASLPTPFGPVTMTLNGSFDPLTQQVVFDSGSLTAPAPFVYGLGAVGPALTTMTALQNSGTAFSGAVQSGNLLGAAGALLQAPGNAVTGFLFGQTAISQSIPGPSNLGYESVGISVPVGGLLAPLQPVTVTLTPTSGMPTAIQLSGTQFGGLLPALLNGF
>NC_021251.1|WP_003408141.1|1848476_1849532_-|DUF2236-domain-containing-protein
MTVASRTSADPLGPDSLTWKYFGDLRTGMMGVWIGAIQNMYPELGAGVEEHSILLREPLQRVARSVYPIMGVVYDGDRAAQTGQQIKGYHRTIKGVDAEGRRYHALNPDTFYWAHATFFMLVIKVAEYFCGGLTEAEKHQLFEEHVRWYRMYGMSMRPVPKSWEDFQDYWDRVCRDKLEINQATVDILQMRIPKPRFVLMPTPIWDQLFKPLIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVFGKVVELAFLAVPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFMAPPRDRQGLPMHYFPPRSHRFTRSALDPAKALMERAGALVHSTLSLAGVRPARGPSRAA
>NC_021251.1|WP_003408112.1|1847683_1848466_+|RNA-methyltransferase
MLTERSARVATAVKLHRHVGRRRAGRFLAEGPNLVAAALARGLVREVFVTEVAARRHELLLAAHEASVHLVTERAAKALSDTVTPAGLVAVCDLPATRLEDVLAGSPQLIAVTVEIREPGNAGTVIRIADAMGAAAVILAGRSVDPYNGKCLRASTGSIFAIPVVVAPDVGAAIADLRAAGLQVLATAVDGEMALDDADRLLAEPTAWLFGPEAHGLSAEIAALADHRVHIPMSGGAESLNVAAAAAICLYESARALGRR
>NC_021251.1|WP_003408108.1|1847261_1847651_+|50S-ribosomal-protein-L20
MARVKRAVNAHKKRRSILKASRGYRGQRSRLYRKAKEQQLHSLNYAYRDRRARKGEFRKLWIARINAAARLNDITYNRLIQGLKAAGVEVDRKNLADIAISDPAAFTALVDVARAALPEDVNAPSGEAA
>NC_021251.1|WP_003408106.1|1847005_1847200_+|50S-ribosomal-protein-L35
MPKAKTHSGASKRFRRTGTGKIVRQKANRRHLLEHKPSTRTRRLDGRTVVAANDTKRVTSLLNG
>NC_021251.1|WP_003901217.1|1846350_1846956_+|translation-initiation-factor-IF-3
MSTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEAAQKARESRRNQQQTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFIETSAKQDGRNMTMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN
>NC_021251.1|WP_003898960.1|1859673_1860732_+|N-acetyl-gamma-glutamyl-phosphate-reductase
MQNRQVANATKVAVAGASGYAGGEILRLLLGHPAYADGRLRIGALTAATSAGSTLGEHHPHLTPLAHRVVEPTEAAVLGGHDAVFLALPHGHSAVLAQQLSPETLIIDCGADFRLTDAAVWERFYGSSHAGSWPYGLPELPGARDQLRGTRRIAVPGCYPTAALLALFPALAADLIEPAVTVVAVSGTSGAGRAATTDLLGAEVIGSARAYNIAGVHRHTPEIAQGLRAVTDRDVSVSFTPVLIPASRGILATCTARTRSPLSQLRAAYEKAYHAEPFIYLMPEGQLPRTGAVIGSNAAHIAVAVDEDAQTFVAIAAIDNLVKGTAGAAVQSMNLALGWPETDGLSVVGVAP
>NC_021251.1|WP_003408160.1|1860728_1861943_+|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ
MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFADTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVVHEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPSLATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTNDTVLLLSSGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDALVAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFNGAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEENSAYSS
>NC_021251.1|WP_003408161.1|1861939_1862824_+|acetylglutamate-kinase
MSRIEALPTHIKAQVLAEALPWLKQLHGKVVVVKYGGNAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIEGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFTAVRRSVTVDGVATDIGLVGDVDQVNTAAMLDLVAAGRIPVVSTLAPDADGVVHNINADTAAAAVAEALGAEKLLMLTDIDGLYTRWPDRDSLVSEIDTGTLAQLLPTLESGMVPKVEACLRAVIGGVPSAHIIDGRVTHCVLVELFTDAGTGTKVVRG
>NC_021251.1|WP_003408163.1|1862820_1864023_+|acetylornithine-transaminase
MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVTDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYATEPGIALAEELVALLGADQRTRVFFCNSGAEANEAAFKLSRLTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYGDVDALAAAVDDHTAAVFLEPIMGESGVVVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVLASDGLVRRAEVLGKSLRHGIEALGHPLIDHVRGRGLLLGIALTAPHAKDAEATARDAGYLVNAAAPDVIRLAPPLIIAEAQLDGFVAALPAILDRAVGAP
>NC_021251.1|WP_003408165.1|1864019_1864943_+|ornithine-carbamoyltransferase
MIRHFLRDDDLSPAEQAEVLELAAELKKDPVSRRPLQGPRGVAVIFDKNSTRTRFSFELGIAQLGGHAVVVDSGSTQLGRDETLQDTAKVLSRYVDAIVWRTFGQERLDAMASVATVPVINALSDEFHPCQVLADLQTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVAAPEGFLPDPSVRAAAERRAQDTGASVTVTADAHAAAAGADVLVTDTWTSMGQENDGLDRVKPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVWDEAENRLHAQKALLVWLLERS
>NC_021251.1|WP_003408178.1|1864939_1865452_+|arginine-repressor
MSRAKAAPVAGPEVAANRAGRQARIVAILSSAQVRSQNELAALLAAEGIEVTQATLSRDLEELGAVKLRGADGGTGIYVVPEDGSPVRGVSGGTDRMARLLGELLVSTDDSGNLAVLRTPPGAAHYLASAIDRAALPQVVGTIAGDDTILVVAREPTTGAQLAGMFENLR
>NC_021251.1|WP_003408179.1|1865460_1866657_+|argininosuccinate-synthase
MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEHMDVIRQRALDCGAVEAVVVDARDEFAEGYCLPTVLNNALYMDRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDIYAYTEDPTINWGVPDEVIVGFERGVPVSVDGKPVSMLAAIEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRQTDQRWAELVYDGLWYSPLKAALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAESLYDFNLATYDEGDSFDQSAARGFVYVHGLSSKLAARRDLR
>NC_021251.1|WP_003408180.1|1866736_1868149_+|argininosuccinate-lyase
MSTNEGSLWGGRFAGGPSDALAALSKSTHFDWVLAPYDLTASRAHTMVLFRAGLLTEEQRDGLLAGLDSLAQDVADGSFGPLVTDEDVHAALERGLIDRVGPDLGGRLRAGRSRNDQVAALFRMWLRDAVRRVATGVLDVVGALAEQAAAHPSAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPYGSGALAGSSLGLDPDAIAADLGFSAAADNSVDATAARDFAAEAAFVFAMIAVDLSRLAEDIIVWSSTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGLVASLTFNVQRMAELAPAGYTLATDLAEWLVRQGVPFRSAHEAAGAAVRAAEQRGVGLQELTDDELAAISPELTPQVREVLTIEGSVSARDCRGGTAPGRVAEQLNAIGEAAERLRRQLVR
>NC_021251.1|WP_003408181.1|1868257_1869319_+|type-III-polyketide-synthase
MSVIAGVFGALPPYRYSQRELTDSFVSIPDFEGYEDIVRQLHASAKVNSRHLVLPLEKYPKLTDFGEANKIFIEKAVDLGVQALAGALDESGLRPEDLDVLITATVTGLAVPSLDARIAGRLGLRADVRRVPLFGLGCVAGAAGVARLHDYLRGAPDGVAALVSVELCSLTYPGYKPTLPGLVGSALFADGAAAVVAAGVKRAQDIGADGPDILDSRSHLYPDSLRTMGYDVGSAGFELVLSRDLAAVVEQYLGNDVTTFLASHGLSTTDVGAWVTHPGGPKIINAITETLDLSPQALELTWRSLGEIGNLSSASVLHVLRDTIAKPPPSGSPGLMIAMGPGFCSELVLLRWH
>NC_021251.1|WP_003902218.1|1869401_1875782_+|type-I-polyketide-synthase
MNSTPEDLVKALRRSLKQNERLKRENRDLLARTTEPVAVVGMGCRYPGGVDSPETLWELVAHGRDAVSEFPADRGWDVAGLFDPDPDAVGKSYTRCGGFLTDVAGFDAEFFGIAPSEALAMDPQQRLLLEVSWEALERAGIDPITLRGSQTGVFAGVFHGSYGGQGRVPGDLERYGLRGSTLSVASGRVAYVLGLQGPAVSVDTACSSSLVALHLAVQSLRLGECDLALVGGVTVMATPAMFIEFSRQRALSADGRCKAYAGAADGTAFAEGAGVLVLARLADARRLGHPVLALVRGSAVNQDGASNGLATPNGPAQQRVITAALASARLGVADVDVVEGHGTGTTLGDPIEAQAILATYGQRPADRPLWLGSIKSNIGHTSAAAGVAGVIKMVQAMRHGVLPKTLHVDVPTPHVDWSAGAVSLLTEPRPWHVPGRPRRAGVSSFGISGTNAHVILEEAPAVEPVGAAHGNDPVAVPWVLSARSAQALTNQARRLLAWVGADENVRPLDVGWSLVNTRSLFDHRAVVVGADRTQLMEGLTGLAAGVPGADVVAGRAQTVGKTAFVFPGQGAQWLGMGAQLCATAPVFAEHIHRCERALREHVEWSLLDVLRGAPGAPGLDRVDVVQPALWAVMVSLAELWRSVGVVPDAVIGHSQGEIAAAYVAGALSLRDAAAVVALRSRLLVRLGGAGGMVSLACGQPQAEKLASQWGDRLNIAAVNGVSSVVLAGETDAVTELMQRCEAEGIRARRIDVDYASHSAQVDAIREELIAALRGIEPRTSTVAFFSTVTGELMDTAGVNAEYWYRSIRQPVQFARAVRNAFDGGYRVFVESSPHPVLIAGIEETLVDCDRGATGEPIVIPTLGRDDGGVGRFWLSAGQAHVAGVGVDWRAAFADLGGRRVELPTYAFARQRFWLDGLGAVGGDLGGVGLVGAEHGLLAAVVQRPDSGGVVLTGRISVVAAPWLADHAVGPVVLFPGTGFVELALRAGDEVGCSVLQELTLQAPLVLPADGVRVQVVVGGVEQSGTRNVWVYSAAGQADSSPGWTLHAQGVLGVGSVQPAAELSVWPPVGARAMDVADGYQVLAARGYGYGPAFRGLQALWRRGAEVFADVTLPEGVPIRGFGIHPAVLDAALHAWGIVEGEQQTMLPFSWQGVCLHASGAARVRVRLAPVGRGAVSVELADPQGLPVLSVRQLMVRPVSAAALSRSTAGDRGLLEMIWTPVPLEGGDIGDDAVVWELPPHAGAQAGGDVLAAVYRGVHEVLEVLQSWLASDATGLGVVVTRGAVGPVDDDVTDLAGAAVWGLVRSAQAEHPGRVVLVDTDGSVAVEDAVGFGARSGEPQLVVRRGRVYAARLAPVAAGLTLPSASAGGWRLVAGGGGTLADVVVAPVAPVELATGQVRVAVGAVGVNFRDVLVALGMYPGGGELGVDGAGVVVEVGPGVTGLAVGDRVMGLLGLVGSEAVVDARLVTMVPAGWSLVEAAAVPVAFLTAFYGLSVLAEVAAGQKVLVHAGTGGVGMAAVSLARYWGAEVFVTASRAKWDTLRAMGFDDIHISDSRSLEFEEAFLRATEGSGVDVVLNSLAGEFTDASLRLLPSGGRFIELGKTDIRDGQTVAERHRGVRYRAFDLVEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDGPGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLREGGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRAKVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGLSVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDRAALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVISNAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLAEHLDSRLVTASGSDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLTSLTTEDDDIAAATESQLFAILDEELGS

Crispr_ID: NC_021251_6

• CRISPR_ID: NC_021251_6
• CRISPR_location: 2073572-2073826
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NC_021251_6

Consensus_repeat	Method
GCCNCCGTCGCCGCCNNTGCC	CRT

spacers of NC_021251_6

>6.1|2073593|39|NC_021251|CRT
ACCGCCGGGGGCGAAGACGCCGGTACCGGCGGACCCGGC
>6.2|2073653|18|NC_021251|CRT
GATCAGCCCGACGGCGTT
>6.3|2073692|30|NC_021251|CRT
TCGGAGAAAGCCGTCGGTTTGCACGCTGTT
>6.4|2073743|18|NC_021251|CRT
GATCAGCGTCCCGCCGGT
>6.5|2073782|24|NC_021251|CRT
ATCGAAGAAGCTGAACCCGCCGTT

CRISPR arrays and Neighbor proteins around NC_021251_6

CRISPR arrays

The CRISPR arrays of NC_021251_6

>merge|NC_021251|6|2073572-2073826|CRT
GCCTCCGTTCCCGCCACTGCCACCGCCGGGGGCGAAGACGCCGGTACCGGCGGACCCGGCGCCTCCGGCGCCACCGTTGCCGATCAGCCCGACGGCGTTGCCGCCGTCGCCGCCGTGGCCTCGGAGAAAGCCGTCGGTTTGCACGCTGTTGCCGCCGTCGCCGCCGTTGCCGATCAGCGTCCCGCCGGTGCCGCCGTCGCCGCCGTTGCCATCGAAGAAGCTGAACCCGCCGTTACCGCCGTCGCCGAACATCCC

>NC_021251|6|2|2073572-2073826|CRT
GCCTCCGTTCCCGCCACTGCC	ACCGCCGGGGGCGAAGACGCCGGTACCGGCGGACCCGGC
GCCTCCGGCGCCACCGTTGCC	GATCAGCCCGACGGCGTT
GCCGCCGTCGCCGCCGTGGCC	TCGGAGAAAGCCGTCGGTTTGCACGCTGTT
GCCGCCGTCGCCGCCGTTGCC	GATCAGCGTCCCGCCGGT
GCCGCCGTCGCCGCCGTTGCC	ATCGAAGAAGCTGAACCCGCCGTT
ACCGCCGTCGCCGAACATCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003409255.1|2065112_2065979_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_021251.1|WP_003899046.1|2076000_2077368_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NC_021251.1|WP_003905666.1|2065983_2067870_-|CocE/NonD-family-hydrolase	unknown	unknown	gnl|CDD|273375
NC_021251.1|WP_003900418.1|2061159_2063985_+|aminomethyl-transferring-glycine-dehydrogenase	unknown	unknown	gnl|CDD|235432
NC_021251.1|WP_003900419.1|2074963_2076001_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NC_021251.1|WP_003409244.1|2060123_2060801_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133380
NC_021251.1|WP_003409301.1|2081459_2081876_-|transcriptional-repressor-BlaI	unknown	unknown	gnl|CDD|226207
NC_021251.1|WP_003409242.1|2059281_2059776_+|bifunctional-nuclease-family-protein	unknown	unknown	gnl|CDD|376830
NC_021251.1|WP_003900420.1|2077541_2078978_-|GuaB1-family-IMP-dehydrogenase-related-protein	unknown	unknown	gnl|CDD|181127
NC_021251.1|WP_003901265.1|2067885_2069919_-|solute-binding-protein	unknown	unknown	gnl|CDD|238733
NC_021251.1|WP_003409273.1|2072539_2072935_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|224761
NC_021251.1|WP_003899049.1|2083237_2084971_+|urease-subunit-alpha	unknown	unknown	gnl|CDD|237304
NC_021251.1|WP_003409284.1|2079013_2080465_-|NADP-dependent-phosphogluconate-dehydrogenase	unknown	unknown	gnl|CDD|236453
NC_021251.1|WP_003409308.1|2082923_2083238_+|urease-subunit-beta	unknown	unknown	gnl|CDD|106171
NC_021251.1|WP_003409254.1|2064211_2065072_-|haloalkane-dehalogenase	unknown	unknown	gnl|CDD|179554
NC_021251.1|WP_003409276.1|2072931_2073195_-|antitoxin	unknown	unknown	unknown
NC_021251.1|WP_003905667.1|2070038_2072264_-|malate-synthase-G	unknown	unknown	gnl|CDD|235097
NC_021251.1|WP_003409298.1|2080494_2081445_-|M56-family-metallopeptidase	unknown	unknown	gnl|CDD|320685
NC_021251.1|WP_003902187.1|2082153_2082576_+|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NC_021251.1|WP_003409305.1|2082624_2082927_+|urease-subunit-gamma	unknown	unknown	gnl|CDD|376347

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003409255.1|2065112_2065979_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	6.65147e-19
NC_021251.1|WP_003899046.1|2076000_2077368_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	8.70643e-128
NC_021251.1|WP_003905666.1|2065983_2067870_-|CocE/NonD-family-hydrolase	gnl|CDD|273375	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c., putative hydrolase, CocE/NonD family. This model represents a protein subfamily that includes the cocaine esterase CocE, several glutaryl-7-ACA acylases, and the putative diester hydrolase NonD of Streptomyces griseus (all hydrolases). This family shows extensive, low-level similarity to a family of xaa-pro dipeptidyl-peptidases, and local similarity by PSI-BLAST to many other hydrolases. [Unknown function, Enzymes of unknown specificity].	0
NC_021251.1|WP_003900418.1|2061159_2063985_+|aminomethyl-transferring-glycine-dehydrogenase	gnl|CDD|235432	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase.	0
NC_021251.1|WP_003900419.1|2074963_2076001_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.8319e-96
NC_021251.1|WP_003409244.1|2060123_2060801_+|MerR-family-transcriptional-regulator	gnl|CDD|133380	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators. Helix-turn-helix (HTH) transcription regulator GlnR and related proteins, N-terminal domain. The GlnR and TnrA (also known as ScgR) proteins have been shown to regulate expression of glutamine synthetase as well as several genes involved in nitrogen metabolism. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	6.61772e-22
NC_021251.1|WP_003409301.1|2081459_2081876_-|transcriptional-repressor-BlaI	gnl|CDD|226207	COG3682, COG3682, Predicted transcriptional regulator [Transcription].	1.25443e-40
NC_021251.1|WP_003409242.1|2059281_2059776_+|bifunctional-nuclease-family-protein	gnl|CDD|376830	pfam02577, DNase-RNase, Bifunctional nuclease. This family is a bifunctional nuclease, with both DNase and RNase activity. It forms a wedge-shaped dimer, with each monomer being triangular in shape. A large groove at the thick end of the wedge contains a possible active site.	1.28808e-61
NC_021251.1|WP_003900420.1|2077541_2078978_-|GuaB1-family-IMP-dehydrogenase-related-protein	gnl|CDD|181127	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein.	0
NC_021251.1|WP_003901265.1|2067885_2069919_-|solute-binding-protein	gnl|CDD|238733	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the members of this subgroup. All members of this subgroup however have a conserved MIDAS motif. .	3.79869e-39
NC_021251.1|WP_003409273.1|2072539_2072935_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|224761	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	1.16634e-21
NC_021251.1|WP_003899049.1|2083237_2084971_+|urease-subunit-alpha	gnl|CDD|237304	PRK13206, ureC, urease subunit alpha; Reviewed.	0
NC_021251.1|WP_003409284.1|2079013_2080465_-|NADP-dependent-phosphogluconate-dehydrogenase	gnl|CDD|236453	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase.	0
NC_021251.1|WP_003409308.1|2082923_2083238_+|urease-subunit-beta	gnl|CDD|106171	PRK13202, ureB, urease subunit beta; Reviewed.	3.42156e-64
NC_021251.1|WP_003409254.1|2064211_2065072_-|haloalkane-dehalogenase	gnl|CDD|179554	PRK03204, PRK03204, haloalkane dehalogenase; Provisional.	0
NC_021251.1|WP_003409305.1|2082624_2082927_+|urease-subunit-gamma	gnl|CDD|376347	pfam00547, Urease_gamma, Urease, gamma subunit. Urease is a nickel-binding enzyme that catalyzes the hydrolysis of urea to carbon dioxide and ammonia.	1.78898e-65
NC_021251.1|WP_003905667.1|2070038_2072264_-|malate-synthase-G	gnl|CDD|235097	PRK02999, PRK02999, malate synthase G; Provisional.	0
NC_021251.1|WP_003409298.1|2080494_2081445_-|M56-family-metallopeptidase	gnl|CDD|320685	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	3.1451e-26
NC_021251.1|WP_003902187.1|2082153_2082576_+|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	5.29844e-31

Protein sequences

>NC_021251.1|WP_003409276.1|2072931_2073195_-|antitoxin
MSKRLQVLLDPDEWEELREIARRHRTTVSEWVRRTLREAREREPRGDLDMKLRSVRAAARHEFPTADVEQMLEEIERGRGAEREGSR
>NC_021251.1|WP_003409273.1|2072539_2072935_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MILVDSNIPMYLVGASHPHKLDAQRLLESALSGGERLVTDAEVLQEICHRYVAIKRREAIQPAFDAIIGVVDEVLPIERTDVEHARDALLRYQTLSARDALHIAVMAHHDITRLMSFDRGFDSYPGIKRLA
>NC_021251.1|WP_003905667.1|2070038_2072264_-|malate-synthase-G
MTDRVSVGNLRIARVLYDFVNNEALPGTDIDPDSFWAGVDKVVADLTPQNQALLNARDELQAQIDKWHRRRVIEPIDMDAYRQFLTEIGYLLPEPDDFTITTSSVDAEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVIPETDGAEKGPTYNKVRGDKVIAYARKFLDDSVPLSSGSFGDATGFTVQDGQLVVALPDKSTGLANPGQFAGYTGAAESPTSVLLINHGLHIEILIDPESQVGTTDRAGVKDVILESAITTIMDFEDSVAAVDAADKVLGYRNWLGLNKGDLAAAVDKDGTAFLRVLNRDRNYTAPGGGQFTLPGRSLMFVRNVGHLMTNDAIVDTDGSEVFEGIMDALFTGLIAIHGLKASDVNGPLINSRTGSIYIVKPKMHGPAEVAFTCELFSRVEDVLGLPQNTMKIGIMDEERRTTVNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMVRKGTMKSQPWILAYEDHNVDAGLAAGFSGRAQVGKGMWTMTELMADMVETKIAQPRAGASTAWVPSPTAATLHALHYHQVDVAAVQQGLAGKRRATIEQLLTIPLAKELAWAPDEIREEVDNNCQSILGYVVRWVDQGVGCSKVPDIHDVALMEDRATLRISSQLLANWLRHGVITSADVRASLERMAPLVDRQNAGDVAYRPMAPNFDDSIAFLAAQELILSGAQQPNGYTEPILHRRRREFKARAAEKPAPSDRAGDDAAR
>NC_021251.1|WP_003901265.1|2067885_2069919_-|solute-binding-protein
MGRHSKPDPEDSVDDLSDGHAAEQQHWEDISGSYDYPGVDQPDDGPLSSEGHYSAVGGYSASGSEDYPDIPPRPDWEPTGAEPIAAAPPPLFRFGHRGPGDWQAGHRSADGRRGVSIGVIVALVAVVVMVAGVILWRFFGDALSNRSHTAAARCVGGKDTVAVIADPSIADQVKESADSYNASAGPVGDRCVAVAVTSAGSDAVINGFIGKWPTELGGQPGLWIPSSSISAARLTGAAGSQAISDSRSLVISPVLLAVRPELQQALANQNWAALPGLQTNPNSLSGLDLPAWGSLRLAMPSSGNGDAAYLAGEAVAAASAPAGAPATAGIGAVRTLMGARPKLADDSLTAAMDTLLKPGDVATAPVHAVVTTEQQLFQRGQSLSDAENTLGSWLPPGPAAVADYPTVLLSGAWLSQEQTSAASAFARYLHKPEQLAKLARAGFRVSDVKPPSSPVTSFPALPSTLSVGDDSMRATLADTMVTASAGVAATIMLDQSMPNDEGGNSRLSNVVAALENRIKAMPPSSVVGLWTFDGREGRTEVPAGPLADPVNGQPRPAALTAALGKQYSSGGGAVSFTTLRLIYQEMLANYRVGQANSVLVITAGPHTDQTLDGPGLQDFIRKSADPAKPIAVNIIDFGADPDRATWEAVAQLSGGSYQNLETSASPDLATAVNIFLS
>NC_021251.1|WP_003905666.1|2065983_2067870_-|CocE/NonD-family-hydrolase
MTRRGGSDAAWYSAPDQRSAYPRYRGMRYSSCYVTMRDGVRIAIDLYLPAGLTSAARLPAILHQTRYYRSLQLRWPLRMLLGGKPLQHIAADKRRRRRFVASGYAWVDVDVRGSGASFGARVCEWSSDEIRDGAEIVDWIVRQPWCNGTVAALGNSYDGTSAELLLVNQHPAVRVIAPRFSLFDVYTDIAFPGGIHAAWFTDTWGRYNEALDRNALHEVVGWWAKLPVTGMQPVQEDRDRSLRDGAIAAHRGNYDVHQIAGSLTFRDDVSASDPYRGQPDARLEPIGTPIESGSINLISPHNYWRDVQASGAAIYSYSGWFDGGYAHAAIKRFLTVSTPGSHLILGPWNHTGGWRVDPLRGLSRPDFDHDGELLRFIDHHVKGADTGIGSEPPVHYFTMVENRWKSADTWPPPATTQSYYLSADRQLRPDAPDCDSGADEYVVDQTAGTGERSRWRSQVGIGGHVCYPDRKAQDAKLLTYTSAPLDHPLEVTGHVVVTLFITSTSSDGTFFVYLEDVDPRGRVAYITEGQLRAIHRRLSDGPPPYRQVVPYRTFASGDAWPLVPGEIARLTFDLLPTSYLFQPGHRIRIAIAGADASHFAILPGCAPTVRVYRSRMHASRIDLPVIQP
>NC_021251.1|WP_003409255.1|2065112_2065979_+|alpha/beta-hydrolase
MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD
>NC_021251.1|WP_003409254.1|2064211_2065072_-|haloalkane-dehalogenase
MSIDFTPDPQLYPFESRWFDSSRGRIHYVDEGTGPPILLCHGNPTWSFLYRDIIVALRDRFRCVAPDYLGFGLSERPSGFGYQIDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAVERADRVRGVVLGNTWFWPADTLAMKAFSRVMSSPPVQYAILRRNFFVERLIPAGTEHRPSSAVMAHYRAVQPNAAARRGVAEMPKQILAARPLLARLAREVPATLGTKPTLLIWGMKDVAFRPKTIIPRLSATFPDHVLVELPNAKHFIQEDAPDRIAAAIIERFG
>NC_021251.1|WP_003900418.1|2061159_2063985_+|aminomethyl-transferring-glycine-dehydrogenase
MSDHSTFADRHIGLDSQAVATMLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLPPAASEAEALAELRALADANTVAVSMIGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQPEISQGRLEALLNFQTLVTDLTGLEIANASMLDEGTAAAEAMTLMHRAARGPVKRVVVDADVFTQTAAVLATRAKPLGIEIVTADLRAGLPDGEFFGVIAQLPGASGRITDWSALVQQAHDRGALVAVGADLLALTLIAPPGEIGADVAFGTTQRFGVPMGFGGPHAGYLAVHAKHARQLPGRLVGVSVDSDGTPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGAGGLTAIARRVHAHAEAIAGALGDALVHDKYFDTVLARVPGRADEVLARAKANGINLWRVDADHVSVACDEATTDTHVAVVLDAFGVAAAAPAHTDIATRTSEFLTHPAFTQYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMESITWPEFGRQHPFAPASDTAGLRQLVADLQSWLVLITGYDAVSLQPNAGSQGEYAGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVDCHDNGDVDLDDLRAKVGEHAERLSALMITYPSTHGVYEHDIAEICAAVHDAGGQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVRAHLAPFLPGHPFAPELPKGYPVSSAPYGSASILPITWAYIRMMGAEGLRAASLTAITSANYIARRLDEYYPVLYTGENGMVAHECILDLRGITKLTGITVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIGIRAEIDKVGAGEWPVDDNPLRGAPHTAQCLLASDWDHPYTREQAAYPLGTAFRPKVWPAVRRIDGAYGDRNLVCSCPPVEAFA
>NC_021251.1|WP_003409244.1|2060123_2060801_+|MerR-family-transcriptional-regulator
MTQLVTRARSARGSTLGEQPRQDQLDFADHTGTAGDGNDGAAAASGPVQPGLFPDDSVPDELVGYRGPSACQIAGITYRQLDYWARTSLVVPSIRSAAGSGSQRLYSFKDILVLKIVKRLLDTGISLHNIRVAVDHLRQRGVQDLANITLFSDGTTVYECTSAEEVVDLLQGGQGVFGIAVSGAMRELTGVIADFHGERADGGESIAAPEDELASRRKHRDRKIG
>NC_021251.1|WP_003409242.1|2059281_2059776_+|bifunctional-nuclease-family-protein
MGEVRVVGIRVEQPQNQPVLLLREANGDRYLPIWIGQSEAAAIALEQQGVEPPRPLTHDLIRDLIAALGHSLKEVRIVDLQEGTFYADLIFDRNIKVSARPSDSVAIALRVGVPIYVEEAVLAQAGLLIPDESDEEATTAVREDEVEKFKEFLDSVSPDDFKAT
>NC_021251.1|WP_003900419.1|2074963_2076001_-|HlyC/CorC-family-transporter
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAMLTGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAIVVALHVLLGEMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAVSTAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPTIGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLADALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR
>NC_021251.1|WP_003899046.1|2076000_2077368_-|HlyC/CorC-family-transporter
MNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGLVLRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR
>NC_021251.1|WP_003900420.1|2077541_2078978_-|GuaB1-family-IMP-dehydrogenase-related-protein
MRFLDGHPPGYDLTYNDVFIVPNRSEVASRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVILPQDLPIPAVKQTVAFVKSRDLVLDTPVTLAPDDSVSDAMALIHKRAHGVAVVILEGRPIGLVRESSCLGVDRFTRVRDIAVTDYVTAPAGTEPRKIFDLLEHAPVDVAVLTDADGTLAGVLSRTGAIRAGIYTPATDSAGRLRIGAAVGINGDVGAKARALAEAGVDVLVIDTAHGHQVKTLDAIKAVSALDLGLPLAAGNVVSAEGTRDLLKAGANVVKVGVGPGAMCTTRMMTGVGRPQFSAVLECASAARQLGGHIWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRDDQPYKESYGMASKRAVVARTGADNPFDRARKALFEEGISTSRMGLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHERAVVGVQSGAGFAEGHPLPAGW
>NC_021251.1|WP_003409284.1|2079013_2080465_-|NADP-dependent-phosphogluconate-dehydrogenase
MSSSESPAGIAQIGVTGLAVMGSNIARNFARHGYTVAVHNRSVAKTDALLKEHSSDGKFVRSETIPEFLAALEKPRRVLIMVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAMRERGLHFVGAGISGGEEGALNGPSIMPGGPAESYQSLGPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLMRDGLGLTAPAIADVFTEWNNGDLDSYLVEITAEVLRQTDAKTGKPLVDVIVDRAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGSVGQRSAASGLASGKLGEQPADPATFTEDVRQALYASKIVAYAQGFNQIQAGSAEFGWDITPGDLATIWRGGCIIRAKFLNHIKEAFDASPNLASLIVAPYFRGAVESAIDSWRRVVSTAAQLGIPTPGFSSALSYYDALRTARLPAALTQAQRDFFGAHTYGRIDEPGKFHTLWSSDRTEVPV
>NC_021251.1|WP_003409298.1|2080494_2081445_-|M56-family-metallopeptidase
MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLSSFSAGIAIASRLLMPGPDGRPTTSFVGAAGRLGWPLWAAYITVFALTVLVGARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRVLDVAQPLAYCLPGVRSRVVVSEGTLTALADAEVAAILTHERAHLRARHDLVLEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARALVACASGRAPSGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVLVVPTVALAVPWLTQLQRLFIA
>NC_021251.1|WP_003409301.1|2081459_2081876_-|transcriptional-repressor-BlaI
MAKLTRLGDLERAVMDHLWSRTEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVLQIRDDRAHRYAPVHGRDELVAGLMVDALAQAEDSGSRQAALVHFVERVGADEADALRRALAELEAGHGNRPPAGAATET
>NC_021251.1|WP_003902187.1|2082153_2082576_+|PaaI-family-thioesterase
MQPSPDSPAPLNVTVPFDSELGLQFTELGPDGARAQLDVRPKLLQLTGVVHGGVYCAMIESIASMAAFAWLNSHGEGGSVVGVNNNTDFVRSISSGMVYGTAEPLHRGRRQQLWLVTITDDTDRVVARGQVWLQNLEARP
>NC_021251.1|WP_003409305.1|2082624_2082927_+|urease-subunit-gamma
MRLTPHEQERLLLSYAAELARRRRARGLRLNHPEAIAVIADHILEGARDGRTVAELMASGREVLGRDDVMEGVPEMLAEVQVEATFPDGTKLVTVHQPIA
>NC_021251.1|WP_003409308.1|2082923_2083238_+|urease-subunit-beta
MIPGEIFYGSGDIEMNAAALSRLQMRIINAGDRPVQVGSHVHLPQANRALSFDRATAHGYRLDIPAATAVRFEPGIPQIVGLVPLGGRREVPGLTLNPPGRLDR
>NC_021251.1|WP_003899049.1|2083237_2084971_+|urease-subunit-alpha
MARLSRERYAQLYGPTTGDRIRLADTNLLVEVTEDRCGGPGLAGDEAVFGGGKVLRESMGQGRASRADGAPDTVITGAVIIDYWGIIKADIGIRDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIISGNRRIVTAGTVDCHVHLICPQIIVEALAAGTTTIIGGGTGPAEGTKATTVTPGEWHLARMLESLDGWPVNFALLGKGNTVNPDALWEQLRGGASGFKLHEDWGSTPAAIDTCLAVADVAGVQVALHSDTLNETGFVEDTIGAIAGRSIHAYHTEGAGGGHAPDIITVAAQPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRIPEDLAFAESRIRPSTIAAEDVLHDMGAISMIGSDSQAMGRVGEVVLRTWQTAHVMKARRGALEGDPSGSQAADNNRVRRYIAKYTICPAIAHGMDHLIGSVEVGKLADLVLWEPAFFGVRPHVVLKGGAIAWAAMGDANASIPTPQPVLPRPMFGAAAATAAATSVHFVAPQSIDARLADRLAVNRGLAPVADVRAVGKTDLPLNDALPSIEVDPDTFTVRIDGQVWQPQPAAELPMTQRYFLF

Crispr_ID: NC_021251_7

• CRISPR_ID: NC_021251_7
• CRISPR_location: 2156509-2156728
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021251_7

Consensus_repeat	Method
GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	CRISPRCasFinder

spacers of NC_021251_7

>7.1|2156558|122|NC_021251|CRISPRCasFinder
GCGTCGGCAGATTGAACGCACCTAGCGCTGTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAACTGAGGCAAGTTAAACGCACCTACCGTGATGTTGGCTGGTGTC

CRISPR arrays and Neighbor proteins around NC_021251_7

CRISPR arrays

The CRISPR arrays of NC_021251_7

>merge|NC_021251|7|2156509-2156728|CRISPRCasFinder
GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAGCGTCGGCAGATTGAACGCACCTAGCGCTGTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAACTGAGGCAAGTTAAACGCACCTACCGTGATGTTGGCTGGTGTCGTTGTAGCTGGAATCGTCAACGACGGCACCGTCAACCCCGGCAAATCAA

>NC_021251|7|4|2156509-2156728|CRISPRCasFinder
GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	GCGTCGGCAGATTGAACGCACCTAGCGCTGTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAACTGAGGCAAGTTAAACGCACCTACCGTGATGTTGGCTGGTGTC
GTTGTAGCTGGAATCGTCAACGACGGCACCGTCAACCCCGGCAAATCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003900433.1|2162867_2164208_+|lipase-LipD	unknown	unknown	gnl|CDD|365903
NC_021251.1|WP_003409574.1|2144524_2145277_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293840
NC_021251.1|WP_003409584.1|2145796_2148097_+|isocitrate-lyase-family-protein	unknown	unknown	gnl|CDD|215482
NC_021251.1|WP_003905688.1|2167367_2168141_+|YqjF-family-protein	unknown	unknown	gnl|CDD|225897
NC_021251.1|WP_003409666.1|2160218_2161490_-|hypothetical-protein	unknown	unknown	gnl|CDD|273654
NC_021251.1|WP_003899076.1|2141482_2141926_-|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NC_021251.1|WP_003902177.1|2164781_2166644_+|AMP-binding-protein	unknown	unknown	gnl|CDD|171527
NC_021251.1|WP_014585239.1|2138582_2139047_-|DUF4262-domain-containing-protein	unknown	unknown	gnl|CDD|379457
NC_021251.1|WP_003409667.1|2161761_2162877_+|serine-hydrolase	unknown	unknown	gnl|CDD|224594
NC_021251.1|WP_003901285.1|2139222_2141445_-|catalase/peroxidase-HPI	unknown	unknown	gnl|CDD|237891
NC_021251.1|WP_003409577.1|2145254_2145662_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003900434.1|2164244_2164625_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003409684.1|2166651_2167131_-|immunoprotective-protein-Mpt63	unknown	unknown	gnl|CDD|370335
NC_021251.1|WP_003899082.1|2158755_2159220_-|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176863
NC_021251.1|WP_003409566.1|2142039_2142633_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl|CDD|224793
NC_021251.1|WP_087902221.1|2152085_2153347_-|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_021251.1|WP_003409568.1|2142715_2143321_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl|CDD|224793
NC_021251.1|WP_003409686.1|2168144_2168912_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|135631
NC_021251.1|WP_003901288.1|2159317_2160181_+|acyltransferase-family-protein	unknown	unknown	gnl|CDD|153249
NC_021251.1|WP_003409570.1|2143420_2144425_-|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176236

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003900433.1|2162867_2164208_+|lipase-LipD	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	7.07573e-54
NC_021251.1|WP_003409574.1|2144524_2145277_+|MBL-fold-metallo-hydrolase	gnl|CDD|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.95555e-42
NC_021251.1|WP_003409584.1|2145796_2148097_+|isocitrate-lyase-family-protein	gnl|CDD|215482	PLN02892, PLN02892, isocitrate lyase.	2.96208e-144
NC_021251.1|WP_003409666.1|2160218_2161490_-|hypothetical-protein	gnl|CDD|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	4.7592e-11
NC_021251.1|WP_003899076.1|2141482_2141926_-|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	4.92282e-41
NC_021251.1|WP_003902177.1|2164781_2166644_+|AMP-binding-protein	gnl|CDD|171527	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional.	0
NC_021251.1|WP_014585239.1|2138582_2139047_-|DUF4262-domain-containing-protein	gnl|CDD|379457	pfam14081, DUF4262, Domain of unknown function (DUF4262). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 147 and 227 amino acids in length. Some members may be incorrectly annotated as the KatG protein.	7.86857e-31
NC_021251.1|WP_003409667.1|2161761_2162877_+|serine-hydrolase	gnl|CDD|224594	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms].	8.61879e-60
NC_021251.1|WP_003901285.1|2139222_2141445_-|catalase/peroxidase-HPI	gnl|CDD|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NC_021251.1|WP_087902221.1|2152085_2153347_-|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_021251.1|WP_003409684.1|2166651_2167131_-|immunoprotective-protein-Mpt63	gnl|CDD|370335	pfam09167, DUF1942, Domain of unknown function (DUF1942). Members of this family of bacterial proteins assume a beta-sandwich structure consisting of two antiparallel beta-sheets similar to an immunoglobulin-like fold, with an additional small, antiparallel beta-sheet. The longer-stranded beta-sheet is made up of four antiparallel beta-strands. The shorter-stranded beta-sheet consists of five beta-strands, four of these beta-strands form an antiparallel beta-sheet. The exact function of this family of proteins is unknown, though a putative role includes involvement in host-bacterial interactions involved in endocytosis or phagocytosis, possibly during bacterial internalisation.	3.87872e-58
NC_021251.1|WP_003899082.1|2158755_2159220_-|SRPBCC-family-protein	gnl|CDD|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	1.38133e-21
NC_021251.1|WP_003409566.1|2142039_2142633_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl|CDD|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	4.33831e-50
NC_021251.1|WP_003409568.1|2142715_2143321_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl|CDD|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	1.29998e-51
NC_021251.1|WP_003905688.1|2167367_2168141_+|YqjF-family-protein	gnl|CDD|225897	COG3361, COG3361, Uncharacterized conserved protein [Function unknown].	2.68592e-126
NC_021251.1|WP_003409686.1|2168144_2168912_-|SDR-family-oxidoreductase	gnl|CDD|135631	PRK05867, PRK05867, SDR family oxidoreductase.	8.21275e-152
NC_021251.1|WP_003901288.1|2159317_2160181_+|acyltransferase-family-protein	gnl|CDD|153249	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.	4.71059e-64
NC_021251.1|WP_003409570.1|2143420_2144425_-|zinc-binding-dehydrogenase	gnl|CDD|176236	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.67964e-153

Protein sequences

>NC_021251.1|WP_087902221.1|2152085_2153347_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_021251.1|WP_003409584.1|2145796_2148097_+|isocitrate-lyase-family-protein
MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFYELGVKELNGHLLYALGDSEYAAAGGWLERQGIFGLVSDAVNAWREDGQQSIDGIFDQVESRFVAAWEDDAGLMTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA
>NC_021251.1|WP_003409577.1|2145254_2145662_-|hypothetical-protein
MVLSRTSTGRVILVPTQLRFDRWFLPLAVPLGLGPKNSELWVGAGSLHVKMGWAFAADIPLTSITKAEATNARVYAAGVHFGFGRWLVNGSRKGLVALTIDPPEQAKMWKKSMTVRELWVSVTDPDALVTACTAK
>NC_021251.1|WP_003409574.1|2144524_2145277_+|MBL-fold-metallo-hydrolase
MHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR
>NC_021251.1|WP_003409570.1|2143420_2144425_-|zinc-binding-dehydrogenase
MRAVVITKHGDPSVLQVRQRPDPPPPGPGQLRVAVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTVEAVGDGVDPNRVGERVLAGTRFGGYCEIVNVAATDSVVLPDALSFEQGAAVPVNYATAWAALHGYGSLRAGERVLIHAAAGGVGIAAVQFAKAAKAEVHGTASPQKHQKLAEFGVDRAIDYRRDGWWQGLGPYDVVLDALGGTSLRRSYTLLRPGGRLVGYGISNMQHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRRTLEPWIAPLTKALNDGTILPIVHAIVPFAEAPEAHRILAARENVGKVVLVP
>NC_021251.1|WP_003409568.1|2142715_2143321_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MTSTLHRTPLATAGLALVVALGGCGGGGGDSRETPPYVPKATTVDATTPAPAAEPLTIASPMFADGAPIPVQFSCKGANVAPPLTWSSPAGAAELALVVDDPDAVGGLYVHWIVTGIAPGSGSTADGQTPAGGHSVPNSGGRQGYFGPCPPAGTGTHHYRFTLYHLPVALQLPPGATGVQAAQAIAQAASGQARLVGTFEG
>NC_021251.1|WP_003409566.1|2142039_2142633_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MAHAFHRFALAILGLALPVALVAYGGNGDSRKAAPLAPKAAALGRSMPETPTGDVLTISSPAFADGAPIPEQYTCKGANIAPPLTWSAPFGGALVVDDPDAPREPYVHWIVIGIAPGAGSTADGETPGGGISLPNSSGQPAYTGPCPPAGTGTHHYRFTLYHLPAVPPLAGLAGTQAARVIAQAATMQARLIGTYEG
>NC_021251.1|WP_003899076.1|2141482_2141926_-|transcriptional-repressor
MSSIPDYAEQLRTADLRVTRPRVAVLEAVNAHPHADTETIFGAVRFALPDVSRQAVYDVLHALTAAGLVRKIQPSGSVARYESRVGDNHHHIVCRSCGVIADVDCAVGEAPCLTASDHNGFLLDEAEVIYWGLCPDCSISDTSRSHP
>NC_021251.1|WP_003901285.1|2139222_2141445_-|catalase/peroxidase-HPI
MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDIEEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLSWADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPDPMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVVWTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEHPEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQILASGLTVSQLVSTAWAAASSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAGHNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKRLPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKFVQDFVAAWDKVMNLDRFDVR
>NC_021251.1|WP_014585239.1|2138582_2139047_-|DUF4262-domain-containing-protein
MCDHPEATAEEYLDEVYGIMLMHGWAVQHVECERRPFAYTVGLTRRGLPELVVTGLSPRRGQRLLNIAARRALVGDLLTPGMQTTLPAGPLVETVQVTHPDAHLYCAIAIFGDKVTALQLVWADRRGRWPWAADFDEGRGTQPVLGMRATRRSA
>NC_021251.1|WP_003899082.1|2158755_2159220_-|SRPBCC-family-protein
MSGRKFSFEVTKTSSAPAATLFRLVTDGGNWATWAKPIVAQSSWARRGDPAPGGIGAIRKLGMWPVFVQEETVEYEQDRRHVYKLVGARTPVQDYFGEVVLTPNASGGTDLRWSGSFTEKVRGTGPVMRAALGGAVRFFAGQLVKAAEREAVRR
>NC_021251.1|WP_003901288.1|2159317_2160181_+|acyltransferase-family-protein
MFPRWPQQAHNHEVSRADTVSVPRAPTQAEVAAVLRIMTPLRKVIKPKVYGIENVPTERALLVGNHNTLGLVDAPLLAAELWERGRIVRSLGDHAHFKIPGWRDALTRTGVVEGTREITSELMRRGELVMVFPGGAREVNKRKNERYKLVWKNRLGFARLAIQHGYPIVPFASVGAEHGIDIVLDNESPLLAPVQFLAEKLLGTKDGPALVRGVGLTPVPRPERQYYWFGEPIDTTEFMGQQADDNAARRVRARAAAAIEHGIELMLAERAADPNRSLVGRLLRSDA
>NC_021251.1|WP_003409666.1|2160218_2161490_-|hypothetical-protein
MVRLIPSLLAMATVLGGVIGCSAHQPPTPASGCRQLDAFLKWHHGVREFLQSAIDANSRCTGTADGSARKVAIFDWDNTVVKNDIGYATNYYMLQHSLVLQPANQDWHAASRYLTDAAANALSVACGKVVPAGKPLPTGSNALCANEILSLLDGETTTGQPAFVGNNVRRLAGPYAWSNALSAGYTAEELAGFADQAKKQNLAADVGATQQVGTQQVDGYIRVYPQMKDLIGTLQAHGIDTWVVSASPEPIVKVWAGEVGLDDQHVVGVRSVADQSGKLTAHLVGCGGVRDGDDSVMTYLDGKRCWANQVIFGVTGPQAFNQLAADRRQVLAAGDSNSDATFVGDATVVSLVINRNQDDLMCRAYDGLFTRGGKWAINPMFIDPLPQHAPYVCGEAFINPDGSKQPVLRNDGTPIPDQVDSVF
>NC_021251.1|WP_003409667.1|2161761_2162877_+|serine-hydrolase
MDSTVTASIRRMLGLLAATLLLGGCTGQHTTRTAASTTYTPHIKASSQDVLDGAINADEPGCSAAVGVEGKVIWSGVRGIADLASGAKITTDTVFDIASVSKQFTATAILLLVEAGKLTLDDPISQYVPELPDWAQTVTVEQLMHQTSGIPDYVALLAARGYQVSDRTIEAEARQALAAAPELQFKPGTRFDYSNSNYLLLGEIVHRASGQPLPEFLSAEIFQPLGLAMVVDPVGKVPNKAVSYEKGTGGNRSEYRVGNPAWEQIGDGGIQTTPSQLARWADNYRTGSVGGLKLLEAQLAGAVETEPGGGDRYGAGIVSRADGTLDHAGAWAGFVTAFHISSDRRTSVAISCNTDKPDPVAMADALGRLWM
>NC_021251.1|WP_003900433.1|2162867_2164208_+|lipase-LipD
MDVAGLPRLAAGTQAAIIHGMAQPPSLLTTDNGLPFGVQGACDSRFTGVIRAFAGLYPGRKFGGGALSVYIDGRQVVDVWTGWSDRQGKVPWTADTGAMVFSATKGLAATVIHRLVDRGLLSYDAPVAEYWPEFGANGKSEVTVSDVLRHRSGLAHLKGVDKDEVMDHLLMEQKLAAAPLDRQHGKLAYHAVTYGWLLSGLARAVTGKGMRELFREELARPLNTDGIHLGRPPADSPTKAAQTLLPQAKVPTPLLDFIAPKVAGLSFSGLLGAVYFPGILSLLQDDMPFLDGEVPAVNGVVTARALAKTYGALANDGVIDGTRLLSSQAVRGLTGKSELWPDLNLGLPFTYHQGYQSSPVPGLLEGYGHIGLGGTIGWADPETGSAFGYVHNRLLTLLLFDIGSFAGLAALLNSAVVAARRDDPLEVPHFGAPYSEPRHEQAASGA
>NC_021251.1|WP_003900434.1|2164244_2164625_-|hypothetical-protein
MDPADVINPTSTRDAALARVLAYRQRVRARPLLIRATLAVVGGGLFVVSLPMIVLLPELGIPALLVAFRLLAVEAQWAVRAYAWTDWRFTQLREWFHRQVLVTRAAILVGLFLAAVALVWLLVYEF
>NC_021251.1|WP_003902177.1|2164781_2166644_+|AMP-binding-protein
MNDGSRQELRVRSGLLQIEDCLDADGGIALPAGTTLISLIERNIKYVGDLVAYRYLDHARSAAGCALEVTWTQFGMRLAAIGAHVQRFAGPGDCVAILAPQGIDYVCGFYAAIKAGTVAVPLFAPELPGHAERLDTALRDSEPAVILTTAAAKNAVEGFLNNVPRLRKPTVLVIDQIPDREGELFVPVELDIDAVSHLQYTSGSTRPPVGVEITHRAVGTNLVQMILSIDLLNRNTHGVSWLPLYHDMGLSMIGFPAVYGGHSTLMSPTAFVRRPLRWIQALSEGSRTGRVVTAAPNFAYEWAAQRGLPAQGDDVDLSNVVLIIGSEPVSIDAVTTFNKAFAPYGLPRTAFKPSYGIAEATLLVATIDHAAEPTVVYLDPEQLGAGHATRVAPDAPNAVVHVSCGHVARSLWAVIVDPDTGPEAGAELPDGEIGEVWLQGDNVARGYWGRPEETRMTFGARLQSPLAEGSHADGSAIDDTWLRTGDLGVYLDGELYITGRIADLLTIDGRNHYPQDIEATAAEASPMVRRGYITAFTVPASDGDDRNQRLVIIAERAAGTSRSDPRPALDAIRAAVCNRHGLSVADLSFLPAGAIPRTTSGKLARQACRAQYLSGRLGVH
>NC_021251.1|WP_003409684.1|2166651_2167131_-|immunoprotective-protein-Mpt63
MKLTTMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTDTVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIVAMNNGMEDLLIWEP
>NC_021251.1|WP_003905688.1|2167367_2168141_+|YqjF-family-protein
MTAIPGPSGAEPGESRALAGYPVTPPALPRPVIFDQRWTDLTFIHWPVLPDSVAGSYPPGTRPDVFADGMTYVGLVPFRMSSTKLGTALPIPYVGTFPETNVRLYSIDNAGRHGVLFRSLETARLTVVPLTRIGLGIPYAWSRMRMMRSGKHITYHSVRRWPRRGLRSLLTITIGDLVEPTPLEVWLTARWGAHTRKAGRTWWVPNEHKPWPLRAAEIAELNDELIDASGVQPTGDRLRALFSPGVHARFGRPCVVQ
>NC_021251.1|WP_003409686.1|2168144_2168912_-|SDR-family-oxidoreductase
MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAIAARHLDALEKLADEIGTSGGKVVPVCCDVSQHQQVTSMLDQVTAELGGIDIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVNSVSPGYILTELVEPYTEYQPLWEPKIPLGRLGRPEELAGLYLYLASEASSYMTGSDIVIDGGYTCP

Crispr_ID: NC_021251_8

• CRISPR_ID: NC_021251_8
• CRISPR_location: 3113970-3115117
• CRISPR_type: TypeIII
• Repeat_type: II-B,III-A
• Spacer_info: 15 spacers
• Cas_protein_info: csm3gr7,csm2gr11,cas10,cas6

Consensus repeat of NC_021251_8

Consensus_repeat	Method
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	PILER-CR
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CRISPRCasFinder
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CRT

spacers of NC_021251_8

>8.1|3114006|38|NC_021251|PILER-CR,CRISPRCasFinder,CRT
TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
>8.2|3114080|40|NC_021251|PILER-CR,CRISPRCasFinder,CRT
TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
>8.3|3114156|40|NC_021251|PILER-CR,CRISPRCasFinder,CRT
ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
>8.4|3114232|37|NC_021251|PILER-CR,CRISPRCasFinder,CRT
TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
>8.5|3114305|36|NC_021251|PILER-CR,CRISPRCasFinder,CRT
CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
>8.6|3114377|35|NC_021251|PILER-CR,CRISPRCasFinder,CRT
TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
>8.7|3114448|38|NC_021251|PILER-CR,CRISPRCasFinder,CRT
AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
>8.8|3114522|40|NC_021251|PILER-CR,CRISPRCasFinder,CRT
CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
>8.9|3114598|35|NC_021251|PILER-CR,CRISPRCasFinder,CRT
ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
>8.10|3114669|37|NC_021251|PILER-CR,CRISPRCasFinder,CRT
CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
>8.11|3114742|38|NC_021251|PILER-CR,CRISPRCasFinder,CRT
GCGAGAATAAGATTGTCAGGCTGGTGCTGCGTTTCCGT
>8.12|3114816|38|NC_021251|PILER-CR,CRISPRCasFinder,CRT
ACTCTCAACCGCGCCACGCTCAAAAAAAGTGTTATTGA
>8.13|3114890|36|NC_021251|PILER-CR,CRISPRCasFinder,CRT
CCGCTGGGGGCAGGCCCAGGTGGGACGGTTCCTCGC
>8.14|3114962|43|NC_021251|CRISPRCasFinder,CRT
TTCGGGAGCATGCCGCAGCTGCGGATGTGGTGCTGGATTTCGA
>8.15|3115041|41|NC_021251|CRT
ACGTTGGAAGCGTTTCGAGCGTACGGACTTTCCGGATGCAG

CRISPR arrays and Neighbor proteins around NC_021251_8

CRISPR arrays

The CRISPR arrays of NC_021251_8

>merge|NC_021251|8|3113970-3115117|PILER-CR,CRISPRCasFinder,CRT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAAGTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGACTGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGACATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGACCCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACAGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACTTGCGCGCACAACGCATCCGCCATCCACGGGGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAATGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACGCGAGAATAAGATTGTCAGGCTGGTGCTGCGTTTCCGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACTCTCAACCGCGCCACGCTCAAAAAAAGTGTTATTGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGCTGGGGGCAGGCCCAGGTGGGACGGTTCCTCGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTCGGGAGCATGCCGCAGCTGCGGATGTGGTGCTGGATTTCGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGTTGGAAGCGTTTCGAGCGTACGGACTTTCCGGATGCAGGTTTCCGTCCCCTCTCTGAACCGCCCCGGCATGTCC

>NC_021251|8|2|3113970-3114961|PILER-CR
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
GTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGAC	TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGAC	ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGAC	CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GCGAGAATAAGATTGTCAGGCTGGTGCTGCGTTTCCGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTCTCAACCGCGCCACGCTCAAAAAAAGTGTTATTGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGCTGGGGGCAGGCCCAGGTGGGACGGTTCCTCGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NC_021251|8|5|3113970-3115040|CRISPRCasFinder
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
GTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGAC	TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGAC	ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGAC	CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GCGAGAATAAGATTGTCAGGCTGGTGCTGCGTTTCCGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTCTCAACCGCGCCACGCTCAAAAAAAGTGTTATTGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGCTGGGGGCAGGCCCAGGTGGGACGGTTCCTCGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTCGGGAGCATGCCGCAGCTGCGGATGTGGTGCTGGATTTCGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NC_021251|8|3|3113970-3115117|CRT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
GTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGAC	TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGAC	ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGAC	CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GCGAGAATAAGATTGTCAGGCTGGTGCTGCGTTTCCGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTCTCAACCGCGCCACGCTCAAAAAAAGTGTTATTGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGCTGGGGGCAGGCCCAGGTGGGACGGTTCCTCGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTCGGGAGCATGCCGCAGCTGCGGATGTGGTGCTGGATTTCGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGTTGGAAGCGTTTCGAGCGTACGGACTTTCCGGATGCAG
GTTTCCGTCCCCTCTCTGAACCGCCCCGGCATGTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003414195.1|3110923_3111532_+|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003414198.1|3111602_3113012_+|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NC_021251.1|WP_087902221.1|3115148_3116410_+|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_021251.1|WP_003414489.1|3124859_3125129_-|DUF2277-family-protein	unknown	unknown	gnl|CDD|227839
NC_021251.1|WP_003899491.1|3113008_3113821_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|225806
NC_021251.1|WP_003414181.1|3107651_3108056_+|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003414184.1|3108052_3108244_+|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003899488.1|3108442_3109597_+|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NC_021251.1|WP_003414409.1|3122238_3123123_-|hypothetical-protein	unknown	unknown	gnl|CDD|225162
NC_021251.1|WP_003911993.1|3106798_3107074_+|DUF1778-domain-containing-protein	unknown	unknown	gnl|CDD|226860
NC_021251.1|WP_014584866.1|3121421_3121967_-|DUF1802-family-protein	unknown	unknown	gnl|CDD|226743
NC_021251.1|WP_003912014.1|3120299_3121022_-|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NC_021251.1|WP_003900580.1|3117864_3120303_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	gnl|CDD|187811
NC_021251.1|WP_003917684.1|3107249_3107504_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003414414.1|3123125_3124013_-|hypothetical-protein	unknown	unknown	gnl|CDD|370470
NC_021251.1|WP_003414296.1|3117493_3117868_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl|CDD|273844
NC_021251.1|WP_003899489.1|3109830_3110088_+|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003414190.1|3110192_3110504_+|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003414292.1|3116773_3117484_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NC_021251.1|WP_003910939.1|3124317_3124863_-|DUF1802-family-protein	unknown	unknown	gnl|CDD|226743

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_021251.1|WP_003414296.1|3117493_3117868_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	2.1e-23	77.8	0.2
NC_021251.1|WP_003912014.1|3120299_3121022_-|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	9.8e-88	288.8	0.1
NC_021251.1|WP_003900580.1|3117864_3120303_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	1.9e-238	788.5	0.0
NC_021251.1|WP_003414292.1|3116773_3117484_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	6.2e-81	265.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003899488.1|3108442_3109597_+|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.94329e-16
NC_021251.1|WP_003912014.1|3120299_3121022_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.14295e-72
NC_021251.1|WP_087902221.1|3115148_3116410_+|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_021251.1|WP_003414489.1|3124859_3125129_-|DUF2277-family-protein	gnl|CDD|227839	COG5552, COG5552, Uncharacterized conserved protein [Function unknown].	9.26436e-31
NC_021251.1|WP_003899491.1|3113008_3113821_+|AAA-family-ATPase	gnl|CDD|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	3.94464e-110
NC_021251.1|WP_003414414.1|3123125_3124013_-|hypothetical-protein	gnl|CDD|370470	pfam09407, AbiEi_1, AbiEi antitoxin C-terminal domain. AbiEi_1 is the cognate antitoxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	2.43998e-38
NC_021251.1|WP_003414198.1|3111602_3113012_+|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.41102e-28
NC_021251.1|WP_003414409.1|3122238_3123123_-|hypothetical-protein	gnl|CDD|225162	COG2253, COG2253, Uncharacterized conserved protein [Function unknown].	3.55008e-105
NC_021251.1|WP_003911993.1|3106798_3107074_+|DUF1778-domain-containing-protein	gnl|CDD|226860	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown].	1.95042e-26
NC_021251.1|WP_014584866.1|3121421_3121967_-|DUF1802-family-protein	gnl|CDD|226743	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown].	2.51205e-85
NC_021251.1|WP_003900580.1|3117864_3120303_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NC_021251.1|WP_003414296.1|3117493_3117868_-|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	4.56134e-21
NC_021251.1|WP_003414292.1|3116773_3117484_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	4.36536e-99
NC_021251.1|WP_003910939.1|3124317_3124863_-|DUF1802-family-protein	gnl|CDD|226743	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown].	1.22881e-84

Protein sequences

>NC_021251.1|WP_003899491.1|3113008_3113821_+|AAA-family-ATPase
MMHKLISYYGFSRMPFGRDLAPGMLHRHSAHNEAVARIGWCIADRRIGVITGEVGAGKTVAVRAALASLDRSRHTIIYLPDPTVGVQGIHHRIVASLGGQPLTHHATLAPQAADALAAEQAERGRTPVVVVEEAHLLGYDQLEALRLLTNHDLDSSSPFACLLIGQPTLRRRMKLGVLAALDQRIGLRYAMPPMTDTNTGSYLRHHLKLAGRDDALFSDDAIGLIHQTSRGYPRAVNNLALQALVAAFAADKAIVDESTTRTAIAEVTAD
>NC_021251.1|WP_003414198.1|3111602_3113012_+|DDE-type-integrase/transposase/recombinase
MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELAVALRRENPQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
>NC_021251.1|WP_003414195.1|3110923_3111532_+|hypothetical-protein
MVTVEADVDQVERRLAAGELSCPSCGGVLAGWGRARSRQLRGPAGPVELCPRRSRCTGCGVTHVLLPVSALLRRADTAAVIVSALAAKATSRVGFRRIATDVARPAETVRGWLRRFAERVEAVRSVFTVWLCAVDADPVMPDAGGGGFVDAVVAIGALAAAIGRRFSLPTVSLAETAVAVSGGRLLAPGWPGEWVQHESTLP
>NC_021251.1|WP_003414190.1|3110192_3110504_+|hypothetical-protein
MTYAARDDTTLPKLLAQMRWVVLVDKRQLAVLLLENEGPVASATDTLDTRGDSDYENQPVDAVERLCRRLADQAVRQWGFMQGLKQKLGPGVDVRMKLVEWNR
>NC_021251.1|WP_003899489.1|3109830_3110088_+|hypothetical-protein
MSNVLDAISTEHRPVIEQELENRNPALFDELRRTEKPTNEQSDAVIDVLSDALMKTFGPDWVPNDYGLKIERAIDAYLETWPIYR
>NC_021251.1|WP_003899488.1|3108442_3109597_+|DDE-type-integrase/transposase/recombinase
MVSTTGMGRSTARRMLTGPGLPEPAEQVDGRRLRARGFSDDARALLEHVWALMGMPCGKYLVVMLELWLPLVAAAGDLDKPFATEAAVAELKAMSAATVDRYLKPARERMRIKGISTTKPSPLLRNSITIHTCSDEAPKVPGVIEADTVAHCGPSLIGEFARTLTMTDLVTGWTENASIRNNAAKWILEGIKECQQRFPFPMTVFDSDCGGEFINHDVAGWLQARDIAQTRSRPYQKNDQAHVESKNNHVVRKHAFYWRYDTGEELELLNRLWPLVSLRCNFFTPTKKPVGYTSTVNGRRKRIYDKPATPWQRLQASGVLDAQQLSTVAARIEGFNPADLTRQINAIQMQLLDLAKTKTEALATARHIDLQSLQPSINRLAKAK
>NC_021251.1|WP_003414184.1|3108052_3108244_+|hypothetical-protein
MKTNPRYGPAFYSVMTVLFLALFVLNVCTHGSTLGLISTGGLAVLMGYIGYRGWSGKRHINRQ
>NC_021251.1|WP_003414181.1|3107651_3108056_+|hypothetical-protein
MGRDNGKILDPVVATTGMGRSTARQMLTGPRLPGPAEQVDGRSLRPRGFSDEARALLEHVWALMGMPCGKYLVVMHDLWLPLLTAAGDLDKPLVTEASVAELKATALPGANRMPHWAAGTLPDGFPARAVRTRT
>NC_021251.1|WP_003917684.1|3107249_3107504_-|hypothetical-protein
MTVELGGAVVDGVDDQGAGAVVPGTGHGSDEGIEEKIATETGALLLPVERQASEDEHWDRVGSGWPRPGRDGTRIRSMLPMASA
>NC_021251.1|WP_003911993.1|3106798_3107074_+|DUF1778-domain-containing-protein
MPETLTGRLNFRLSPEQEQALRHAAALTGQSLSGFVLSAAVDHAHDLLARANRIELSEAAFRRFVAALDEPDEAAPELVRLARRKSRIPPH
>NC_021251.1|WP_087902221.1|3115148_3116410_+|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_021251.1|WP_003414292.1|3116773_3117484_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MTTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPGTSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVFRDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFAFSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGTRGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
>NC_021251.1|WP_003414296.1|3117493_3117868_-|type-III-A-CRISPR-associated-protein-Csm2
MSVIQDDYVKQAEVIRGLPKKKNGFELTTTQLRVLLSLTAQLFDEAQQSANPTLPRQLKEKVQYLRVRFVYQSGREDAVKTFVRNAKLLEALEGIGDSRDGLLRFCRYMEALAAYKKYLDPKDK
>NC_021251.1|WP_003900580.1|3117864_3120303_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNPQLIEAIIGCLLHDIGKPVQRAALGYPGRHSAIGRAFMKKVWLRDSRNPSQFTDEVDEADIGVSDRRILDAISYHHSSALRTAAENGRLAADAPAYIAYIADNIAAGTDRRKADSDDGHGASTWDPDTPLYSMFNRFGSGTANLAFAPEMLDDRKPINIPSPRRIEFDKDRYAAIVNKLKAILVDLERSDTYLASLLNVLEATLSFVPSSTDASEVVDVSLFDHLKLTGALGACIWHYLQATGQSDFKSALFDKQDTFYNEKAFLLTTFDVSGIQDFIYTIHSSGAAKMLRARSFYLEMLTEHLIDELLARVGLSRANLNYSGGGHAYLLLPNTESARKSVEQFEREANDWLLENFATRLFIATGSVPLAANDLMRRPNESASQASNRALRYSGLYRELSEQLSAKKLARYSADQLRELNSRDHDGQKGDRECSVCHTVNRTVSADDEPKCSLCQALTAASSQIQSESRRFLLISDGATKGLPLPFGATLTFCSRADADKALQQPQTRRRYAKNKFFAGECLGTGLWVGDYVAQMEFGDYVKRASGIARLGVLRLDVDNLGQAFTHGFMEQGNGKFNTISRTAAFSRMLSLFFRQHINYVLARPKLRPITGDDPARPREATIIYSGGDDVFVVGAWDDVIEFGIELRERFHEFTQGKLTVSAGIGMFPDKYPISVMAREVGDLEDAAKSLPGKNGVALFDREFTFGWDELLSKVIEEKYRHIADYFSGNEERGMAFIYKLLELLAERDDRITKARWVYFLTRMRNPTGDTAPFQQFANRLHQWFQDPTDAKQLKTALHLYIYRTRKEESE
>NC_021251.1|WP_003912014.1|3120299_3121022_-|CRISPR-associated-endoribonuclease-Cas6
MATLGPHLHGVLMESIPADYVQTLHTVPVNPYSQYALARSTTSLEWKISTLTNEARQQIVGPINDAAFAGFRLRASGIATQVTSRSLEQNPLSQFARIFYARPETRKFRVEFLTPTAFKQSGEYVFWPDPRLVFQSLAQKYGAIVDGEEPDPGLIAEFGQSVRLSAFRVASAPFAVGAARVPGFTGSATFTVRGVDTFASYIAALLWFGEFSGCGIKASMGMGAIRVQPLAPREKCVPKP
>NC_021251.1|WP_014584866.1|3121421_3121967_-|DUF1802-family-protein
MTPALKEWSAAVHALLDGRQTVLLRKGGIGEKRFEVAAHEFLLFPTVAHSHAERVRPEHRDLLGPAAADSTDECVLLRAAAKVVAALPVNRPEGLDAIEDLHIWTAESVRADRLDFRPKHKLAVLVVCAIPLAEPVRLARRPEYGGCTSWVQLPVTPTLAAPVHDEAALAEVAARVREAVG
>NC_021251.1|WP_003414409.1|3122238_3123123_-|hypothetical-protein
MAGLTRALVARHALGRAEAYDAALLDVAQDHLLYLLSQTVQFGDNRLVFKGGTSLRKCRLGNVGRFSTDLDFSAPDDEVVLEVCELIDGARVGGFEFGVQSTRGDGRHWQLRVRHTELGEPRIVASVEFARRPLALPSELLAFIQLPIHKAYGFGLPTLPVVAEAEACAEKLARYRRVALARDLYDLNHFASRTIDEPLVRRLWVLKVWGDVVDDRRGTRPLRVEDVLAARSEHDFQPDSIGVLTRPVAMAAWEARVRKRFAFLTDLDADEQRWAACDERHRREVENALAVLRS
>NC_021251.1|WP_003414414.1|3123125_3124013_-|hypothetical-protein
MVSPAGADRRIPTWASRVVSGLARDRPVVVTKEDLTQRLTEAGCGRDPDSAIRELRRIGWLVQLPVKGTWAFIPPGEAAISDPYLPLRSWLARDQNAGFMLAGASAAWHLGYLDRQPDGRIPIWLPPAKRLPDGLASYVSVVRIPWNAADTALLAPRPALLVRRRLDLVAWATGLPALGPEALLVQIATRPASFGPWADLVPHLDDLVADCSDERLERLLSGRPTSAWQRASYLLDSGGEPARGQALLAKRHTEVMPVTRFTTAHSRDRGESVWAPEYQLVDELVVPLLRVIGKA
>NC_021251.1|WP_003910939.1|3124317_3124863_-|DUF1802-family-protein
MTPALKEWSAAVHALLDGRQTVLLRKGGIGEKRFEVAAHEFLLFPTVAHSHAERVRPEHRDLLGPAAADSTDECVLLRAAAKVVAALPVNRPEGLDAIEDLHIWTAESVRADRLDFRPKHRLAVLVVCAIPLAEPVRLARRPEYGGCTSWVQLPVTPTLAAPVHDEAALAEVAARVREAVG
>NC_021251.1|WP_003414489.1|3124859_3125129_-|DUF2277-family-protein
MCRNITELRGLQPPATPVEIAAAARQYVRKVSGITHPSAATAEAFEAAVAEVTATTTRLLDALPPRRQPPKTVPPLRRPDVAARLAGSR

Crispr_ID: NC_021251_9

• CRISPR_ID: NC_021251_9
• CRISPR_location: 3656484-3656602
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021251_9

Consensus_repeat	Method
GCCCCTGTGAGTCGAGTGAGCGGAACGAAC	CRISPRCasFinder

spacers of NC_021251_9

>9.1|3656514|59|NC_021251|CRISPRCasFinder
CTGTGAGTCGAGTGAGCGGAACGAACGAAGTGAGTGACGGGAACGAGACGAACAATCCG

CRISPR arrays and Neighbor proteins around NC_021251_9

CRISPR arrays

The CRISPR arrays of NC_021251_9

>merge|NC_021251|9|3656484-3656602|CRISPRCasFinder
GCCCCTGTGAGTCGAGTGAGCGGAACGAACCTGTGAGTCGAGTGAGCGGAACGAACGAAGTGAGTGACGGGAACGAGACGAACAATCCGGCCCCTGTGAGTCGAGTGAGCGGAACGAAC

>NC_021251|9|6|3656484-3656602|CRISPRCasFinder
GCCCCTGTGAGTCGAGTGAGCGGAACGAAC	CTGTGAGTCGAGTGAGCGGAACGAACGAAGTGAGTGACGGGAACGAGACGAACAATCCG
GCCCCTGTGAGTCGAGTGAGCGGAACGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003906045.1|3656868_3657537_+|septum-formation-inhibitor-Maf	unknown	unknown	gnl|CDD|178901
NC_021251.1|WP_003417121.1|3647421_3649716_+|carbonic-anhydrase	unknown	unknown	gnl|CDD|223732
NC_021251.1|WP_003417158.1|3660818_3661604_-|RNA-polymerase-sigma-factor-SigF	unknown	unknown	gnl|CDD|168831
NC_021251.1|WP_003417152.1|3658467_3658899_+|hypothetical-protein	unknown	unknown	gnl|CDD|225077
NC_021251.1|WP_003417160.1|3661600_3662038_-|anti-sigma-regulatory-factor	unknown	unknown	gnl|CDD|225083
NC_021251.1|WP_003417122.1|3649704_3650874_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NC_021251.1|WP_003417156.1|3659006_3660809_+|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha	unknown	unknown	gnl|CDD|227111
NC_021251.1|WP_003417119.1|3645463_3646132_-|cation-transporter	unknown	unknown	gnl|CDD|223131
NC_021251.1|WP_003901586.1|3646232_3647417_+|CoA-transferase	unknown	unknown	gnl|CDD|367110
NC_021251.1|WP_003417126.1|3651419_3652709_-|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl|CDD|273473
NC_021251.1|WP_003906046.1|3657577_3658471_+|sulfurtransferase	unknown	unknown	gnl|CDD|225450
NC_021251.1|WP_003899995.1|3643310_3645467_+|manganese-exporting-P-type-ATPase-CtpC	unknown	unknown	gnl|CDD|225127
NC_021251.1|WP_003417162.1|3662235_3662649_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003417165.1|3662683_3663061_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003899997.1|3650898_3651423_-|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl|CDD|178534
NC_021251.1|WP_003417179.1|3664494_3664947_-|transcriptional-regulator-LrpA	unknown	unknown	gnl|CDD|214628
NC_021251.1|WP_003900004.1|3663094_3664444_-|L-lysine-6-transaminase	unknown	unknown	gnl|CDD|236224
NC_021251.1|WP_003899998.1|3652662_3653481_+|GtrA-family-protein	unknown	unknown	gnl|CDD|225155
NC_021251.1|WP_003899999.1|3653996_3654797_-|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl|CDD|223417
NC_021251.1|WP_003417130.1|3653435_3653954_-|PH-domain-containing-protein	unknown	unknown	gnl|CDD|367615

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003906045.1|3656868_3657537_+|septum-formation-inhibitor-Maf	gnl|CDD|178901	PRK00148, PRK00148, Maf-like protein; Reviewed.	1.61599e-101
NC_021251.1|WP_003417121.1|3647421_3649716_+|carbonic-anhydrase	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.66696e-123
NC_021251.1|WP_003417158.1|3660818_3661604_-|RNA-polymerase-sigma-factor-SigF	gnl|CDD|168831	PRK07122, PRK07122, RNA polymerase sigma factor SigF; Reviewed.	1.58212e-166
NC_021251.1|WP_003417152.1|3658467_3658899_+|hypothetical-protein	gnl|CDD|225077	COG2166, sufE, Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones].	2.70051e-43
NC_021251.1|WP_003417160.1|3661600_3662038_-|anti-sigma-regulatory-factor	gnl|CDD|225083	COG2172, RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms].	8.06445e-27
NC_021251.1|WP_003417122.1|3649704_3650874_-|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
NC_021251.1|WP_003417156.1|3659006_3660809_+|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NC_021251.1|WP_003417119.1|3645463_3646132_-|cation-transporter	gnl|CDD|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	9.88116e-14
NC_021251.1|WP_003901586.1|3646232_3647417_+|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	4.53796e-144
NC_021251.1|WP_003417126.1|3651419_3652709_-|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl|CDD|273473	TIGR01161, N5-carboxyaminoimidazole_ribonucleotide_synthase, phosphoribosylaminoimidazole carboxylase, PurK protein. Phosphoribosylaminoimidazole carboxylase is a fusion protein in plants and fungi, but consists of two non-interacting proteins in bacteria, PurK and PurE. This model represents PurK, N5-carboxyaminoimidazole ribonucleotide synthetase, which hydrolyzes ATP and converts AIR to N5-CAIR. PurE converts N5-CAIR to CAIR. In the presence of high concentrations of bicarbonate, PurE is reported able to convert AIR to CAIR directly and without ATP. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis].	4.83866e-168
NC_021251.1|WP_003906046.1|3657577_3658471_+|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	2.06494e-107
NC_021251.1|WP_003899995.1|3643310_3645467_+|manganese-exporting-P-type-ATPase-CtpC	gnl|CDD|225127	COG2217, ZntA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NC_021251.1|WP_003417179.1|3664494_3664947_-|transcriptional-regulator-LrpA	gnl|CDD|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	2.51557e-39
NC_021251.1|WP_003899997.1|3650898_3651423_-|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl|CDD|178534	PLN02948, PLN02948, phosphoribosylaminoimidazole carboxylase.	3.89772e-84
NC_021251.1|WP_003900004.1|3663094_3664444_-|L-lysine-6-transaminase	gnl|CDD|236224	PRK08297, PRK08297, L-lysine aminotransferase; Provisional.	0
NC_021251.1|WP_003899998.1|3652662_3653481_+|GtrA-family-protein	gnl|CDD|225155	COG2246, COG2246, Predicted membrane protein [Function unknown].	5.34469e-32
NC_021251.1|WP_003899999.1|3653996_3654797_-|biotin--[acetyl-CoA-carboxylase]-ligase	gnl|CDD|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	1.95486e-68
NC_021251.1|WP_003417130.1|3653435_3653954_-|PH-domain-containing-protein	gnl|CDD|367615	pfam03703, bPH_2, Bacterial PH domain. Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.	1.01198e-16

Protein sequences

>NC_021251.1|WP_003899999.1|3653996_3654797_-|biotin--[acetyl-CoA-carboxylase]-ligase
MTDRDRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQTAGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAETGLKWPNDVLARGGKLAGILAEVAQPFVVLGVGLNVTQAPEEVDPDATSLLDLGVAAPDRNRIASRLLRELEARIIQWRNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIARDIDDQGRLCLDVGGRTVVVSAGDVVHLR
>NC_021251.1|WP_003417130.1|3653435_3653954_-|PH-domain-containing-protein
MSYPENVLAAGEQVVLHRHPHWNRLIWPVVVLVLLTGLAAFGSGFVNSTPWQQIAKNVIHAVIWGIWLVIVGWLTLWPFLSWLTTHFVVTNRRVMFRHGVLTRSGIDIPLARINSVEFRDRIFERIFRTGTLIIESASQDPLEFYNIPRLREVHALLYHEVFDTLGSDESPS
>NC_021251.1|WP_003899998.1|3652662_3653481_+|GtrA-family-protein
MNEVTAGVRELATAIMVSRHLTGVLAGHGSQTVTYHFASILCSSVHSLVVSFADATIARLPGVVQPYAQRHHELIKFAIVGGTTFIIDTAIFYTLKLTVLEPKPVTAKVIAGIVAVIASYVLNREWSFRDRGGRERHHEALLFFAFSGVGVLLSMAPLWFSSYILQLRVPTVSLTMENIADFISAYIIGNLLQMAFRFWAFRRWVFPDEFARNPDKALESALTAGGIAEVFEDVLEGGFEDGNVTLLRAWRNRANRFAQLGDSSEPRVSKTS
>NC_021251.1|WP_003417126.1|3651419_3652709_-|5-(carboxyamino)imidazole-ribonucleotide-synthase
MMAVASSRTPAVTSFIAPLVAMVGGGQLARMTHQAAIALGQNLRVLVTSADDPAAQVTPNVVIGSHTDLAALRRVAAGADVLTFDHEHVPNELLEKLVADGVNVAPSPQALVHAQDKLVMRQRLAAAGVAVPRYAGIKDPDEIDVFAARVDAPIVVKAVRGGYDGRGVRMARDVADARDFARECLADGVAVLVEERVDLRRELSALVARSPFGQGAAWPVVQTVQRDGTCVLVIAPAPALPDDLATAAQRLALQLADELGVVGVLAVELFETTDGALLVNELAMRPHNSGHWTIDGARTSQFEQHLRAVLDYPLGDSDAVVPVTVMANVLGAAQPPAMSVDERLHHLFARMPDARVHLYGKAERPGRKVGHINFLGSDVAQLCERAELAAHWLSHGRWTDGWDPHRASDDAVGVPPACGGRSDEEERRL
>NC_021251.1|WP_003899997.1|3650898_3651423_-|5-(carboxyamino)imidazole-ribonucleotide-mutase
MTPAGERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVSAHRTPEAMFSYARGAAERGLEVIIAGAGGAAHLPGMVAAATPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAGNAGLLAVRMLGAANPQLRARIVAFQDRLADVVAAKDAELQRLAGKLTRD
>NC_021251.1|WP_003417122.1|3649704_3650874_-|acyl-CoA-dehydrogenase
MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
>NC_021251.1|WP_003417121.1|3647421_3649716_+|carbonic-anhydrase
MTIPRSQHMSTAVNSCTEAPASRSQWMLANLRHDVPASLVVFLVALPLSLGIAIASGAPIIAGVIAAVVGGIVAGAVGGSPVQVSGPAAGLTVVVAELIDELGWPMLCLMTIAAGALQIVFGLSRMARAALAIAPVVVHAMLAGIGITIALQQIHVLLGGTSHSSAWRNIVALPDGILHHELHEVIVGGTVIAILLMWSKLPAKVRIIPGPLVAIAGATVLALLPVLQTERIDLQGNFFDAIGLPKLAEMSPGGQPWSHEISAIALGVLTIALIASVESLLSAVGVDKLHHGPRTDFNREMVGQGSANVVSGLLGGLPITGVIVRSSANVAAGARTRMSTILHGVWILLFASLFTNLVELIPKAALAGLLIVIGAQLVKLAHIKLAWRTGNFVIYAITIVCVVFLNLLEGVAIGLVVAIVFLLVRVVRAPVEVKPVGGEQSKRWRVDIDGTLSFLLLPRLTTVLSKLPEGSEVTLNLNADYIDDSVSEAISDWRRAHETRGGVVAIVETSPAKLHHAHARPPKRHFASDPIGLVPWRSARGKDRGSASVLDRIDEYHRNGAAVLHPHIAGLTDSQDPYELFLTCADSRILPNVITASGPGDLYTVRNLGNLVPTDPDDRSVDAALDFAVNQLGVSSVVVCGHSSCAAMTALLEDDPANTTTPMMRWLENAHDSLVVFRNHHPARRSAESAGYPEADQLSIVNVAVQVERLTRHPILATAVAAADLQVIGIFFDISTARVYEVGPNGIICPDEPADRPVDHESAQ
>NC_021251.1|WP_003901586.1|3646232_3647417_+|CoA-transferase
MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHMLAQAVLAALLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQPSDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAENDLTLEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEHNAVFLARP
>NC_021251.1|WP_003417119.1|3645463_3646132_-|cation-transporter
METTTEHRDESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC
>NC_021251.1|WP_003899995.1|3643310_3645467_+|manganese-exporting-P-type-ATPase-CtpC
MTLEVVSDAAGRMRVKVDWVRCDSRRAVAVEEAVAKQNGVRVVHAYPRTGSVVVWYSPRRADRAAVLAAIKGAAHVAAELIPARAPHSAEIRNTDVLRMVIGGVALALLGVRRYVFARPPLLGTTGRTVATGVTIFTGYPFLRGALRSLRSGKAGTDALVSAATVASLILRENVVALTVLWLLNIGEYLQDLTLRRTRRAISELLRGNQDTAWVRLTDPSAGSDAATEIQVPIDTVQIGDEVVVHEHVAIPVDGEVVDGEAIVNQSAITGENLPVSVVVGTRVHAGSVVVRGRVVVRAHAVGNQTTIGRIISRVEEAQLDRAPIQTVGENFSRRFVPTSFIVSAIALLITGDVRRAMTMLLIACPCAVGLSTPTAISAAIGNGARRGILIKGGSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIVAMHKDWEPEQVLAYAASSEIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLLLGSPSLLRAEKVRVSKKASEWVDKLRRQAETPLLLAVDGTLVGLISLRDEVRPEAAQVLTKLRANGIRRIVMLTGDHPEIAQVVADELGIDEWRAEVMPEDKLAAVRELQDDGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETADVALANDDLHRLLDVGDLGERAVDVIRQNYGMSIAVNAAGLLIGAGGALSPVLAAILHNASSVAVVANSSRLIRYRLDR
>NC_021251.1|WP_003906045.1|3656868_3657537_+|septum-formation-inhibitor-Maf
MTRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQVATTLTGTQRIVAADCVVVDCDSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHGVIRLQDNKTVYRAAETAITTVYFGTPSASDLEAYLASGESLRVAGGFTLDGLGGWFIDGVQGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ
>NC_021251.1|WP_003906046.1|3657577_3658471_+|sulfurtransferase
MPLPADPSPTLSAYAHPERLVTADWLSAHMGAPGLAIVESDEDVLLYDVGHIPGAVKIDWHTDLNDPRVRDYINGEQFAELMDRKGIARDDTVVIYGDKSNWWAAYALWVFTLFGHADVRLLNGGRDLWLAERRETTLDVPTKTCTGYPVVQRNDAPIRAFRDDVLAILGAQPLIDVRSPEEYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLYDFINPDDQTVVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTKWGNAVRVPIVAGEEPGVVPVV
>NC_021251.1|WP_003417152.1|3658467_3658899_+|hypothetical-protein
MTAPASLPAPLAEVVSDFAEVQGQDKLRLLLEFANELPALPSHLAESAMEPVPECQSPLFLHVDASDPNRVRLHFSAPAEAPTTRGFASILAAGLDEQPAADILAVPEDFYTELGLAALISPLRLRGMSAMLARIKRRLREAD
>NC_021251.1|WP_003417156.1|3659006_3660809_+|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha
MASHAGSRIARISKVLVANRGEIAVRVIRAARDAGLPSVAVYAEPDAESPHVRLADEAFALGGQTSAESYLDFAKILDAAAKSGANAIHPGYGFLAENADFAQAVIDAGLIWIGPSPQSIRDLGDKVTARHIAARAQAPLVPGTPDPVKGADEVVAFAEEYGLPIAIKAAHGGGGKGMKVARTIDEIPELYESAVREATAAFGRGECYVERYLDKPRHVEAQVIADQHGNVVVAGTRDCSLQRRYQKLVEEAPAPFLTDFQRKEIHDSAKRICKEAHYHGAGTVEYLVGQDGLISFLEVNTRLQVEHPVTEETAGIDLVLQQFRIANGEKLDITEDPTPRGHAIEFRINGEDAGRNFLPAPGPVTKFHPPSGPGVRVDSGVETGSVIGGQFDSMLAKLIVHGADRAEALARARRALNEFGVEGLATVIPFHRAVVSDPAFIGDANGFSVHTRWIETEWNNTIEPFTDGEPLDEDARPRQKVVVEIDGRRVEVSLPADLALSNGGGCDPVGVIRRKPKPRKRGAHTGAAASGDAVTAPMQGTVVKFAVEEGQEVVAGDLVVVLEAMKMENPVTAHKDGTITGLAVEAGAAITQGTVLAEIK
>NC_021251.1|WP_003417158.1|3660818_3661604_-|RNA-polymerase-sigma-factor-SigF
MTARAAGGSASRANEYADVPEMFRELVGLPAGSPEFQRHRDKIVQRCLPLADHIARRFEGRGEPRDDLIQVARVGLVNAAVRFDVKTGSDFVSFAVPTIMGEVRRHFRDNSWSVKVPRRLKELHLRLGTATADLSQRLGRAPSASELAAELGMDRAEVIEGLLAGSSYHTLSIDSGGGSDDDARAITDTLGDVDAGLDQIENREVLRPLLEALPERERTVLVLRFFDSMTQTQIAERVGISQMHVSRLLAKSLARLRDQLE
>NC_021251.1|WP_003417160.1|3661600_3662038_-|anti-sigma-regulatory-factor
MADSDLPTKGRQRGVRAVELNVAARLENLALLRTLVGAIGTFEDLDFDAVADLRLAVDEVCTRLIRSALPDATLRLVVDPRKDEVVVEASAACDTHDVVAPGSFSWHVLTALADDVQTFHDGRQPDVAGSVFGITLTARRAASSR
>NC_021251.1|WP_003417162.1|3662235_3662649_-|hypothetical-protein
MGQIPPQPVRRVLPLMVVPGNGQKWRNRTETEEAMGDTYRDPVDHLRTTRPLAGESLIDVVHWPGYLLIVAGVVGGVGALAAFGTGHHAEGMTFGVVAIVVTVVGLAWLAFEHRRIRKIADRWYTEHPEVRRQRLAG
>NC_021251.1|WP_003417165.1|3662683_3663061_-|hypothetical-protein
MHEVGGPSRGDRLGRDDSEVHSAIRFAVVAAVVGVGFLIMGALLVSTCSGVDTAACGPPQRILLALGGPLILCAAGLWAFLRTYRVWRAEGTWWGWHGAGWFLLTLMVLTLCIGVPPIAGPVMAP
>NC_021251.1|WP_003900004.1|3663094_3664444_-|L-lysine-6-transaminase
MAAVVKSVALAGRPTTPDRVHEVLGRSMLVDGLDIVLDLTRSGGSYLVDAITGRRYLDMFTFVASSALGMNPPALVDDREFHAELMQAALNKPSNSDVYSVAMARFVETFARVLGDPALPHLFFVEGGALAVENALKAAFDWKSRHNQAHGIDPALGTQVLHLRGAFHGRSGYTLSLTNTKPTITARFPKFDWPRIDAPYMRPGLDEPAMAALEAEALRQARAAFETRPHDIACFVAEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGLTGTAWAYQQLDVAPDIVAFGKKTQVCGVMAGRRVDEVADNVFAVPSRLNSTWGGNLTDMVRARRILEVIEAEGLFERAVQHGKYLRARLDELAADFPAVVLDPRGRGLMCAFSLPTTADRDELIRQLWQRAVIVLPAGADTVRFRPPLTVSTAEIDAAIAAVRSALPVVT
>NC_021251.1|WP_003417179.1|3664494_3664947_-|transcriptional-regulator-LrpA
MNEALDDIDRILVRELAADGRATLSELATRAGLSVSAVQSRVRRLESRGVVQGYSARINPEAVGHLLSAFVAITPLDPSQPDDAPARLEHIEEVESCYSVAGEESYVLLVRVASARALEDLLQRIRTTANVRTRSTIILNTFYSDRQHIP

Crispr_ID: NC_021251_10

• CRISPR_ID: NC_021251_10
• CRISPR_location: 3738955-3739634
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 9 spacers

Consensus repeat of NC_021251_10

Consensus_repeat	Method
CCGCCGNNNCCNCCGTNGCCGCC	CRT

spacers of NC_021251_10

>10.1|3738978|52|NC_021251|CRT
GTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATG
>10.2|3739053|58|NC_021251|CRT
CTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCG
>10.3|3739134|43|NC_021251|CRT
GTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATG
>10.4|3739200|79|NC_021251|CRT
GTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGG
>10.5|3739302|34|NC_021251|CRT
GTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCA
>10.6|3739359|61|NC_021251|CRT
GCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACA
>10.7|3739443|31|NC_021251|CRT
AACGCCCACTTCACCGCCGTTGCCGCCGTCA
>10.8|3739497|55|NC_021251|CRT
CAAGGTCACATCACCGGCGGCACCGGCTCCGCCATCACCGGCCTTGCCGCCGTCA
>10.9|3739575|37|NC_021251|CRT
CTTGCCGGCGGTGCCGGCGACCGCGGTGCCGCCGGCG

CRISPR arrays and Neighbor proteins around NC_021251_10

CRISPR arrays

The CRISPR arrays of NC_021251_10

>merge|NC_021251|10|3738955-3739634|CRT
CCGCCGTTGCCGCCGGCACCGCCGTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATGCCGCCGTTGCCGCCGTTGCCGCCCTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCGCCCCCGTTGCCGCCCTTGCCGCCGTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATGCCGCCGTTGCCGCCGTTGCCGCCGTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGGCCGCCGTTACCACCGGCGCCGCCGTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCACCTCCGTTGCCACCGTTGCCGCCGCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACACCGCCGGCCCCACCCTTGCCGCCAACGCCCACTTCACCGCCGTTGCCGCCGTCACCGCCGGCACCCTGGTTGACGGCCAAGGTCACATCACCGGCGGCACCGGCTCCGCCATCACCGGCCTTGCCGCCGTCACCGCCGGCGCCGCCGTCCCCGGCCTTGCCGGCGGTGCCGGCGACCGCGGTGCCGCCGGCGCCGCCACCACCGCCGTCACCGCC

>NC_021251|10|4|3738955-3739634|CRT
CCGCCGTTGCCGCCGGCACCGCC	GTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATG
CCGCCGTTGCCGCCGTTGCCGCC	CTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCG
CCCCCGTTGCCGCCCTTGCCGCC	GTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATG
CCGCCGTTGCCGCCGTTGCCGCC	GTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGG
CCGCCGTTACCACCGGCGCCGCC	GTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCA
CCTCCGTTGCCACCGTTGCCGCC	GCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACA
CCGCCGGCCCCACCCTTGCCGCC	AACGCCCACTTCACCGCCGTTGCCGCCGTCA
CCGCCGGCACCCTGGTTGACGGC	CAAGGTCACATCACCGGCGGCACCGGCTCCGCCATCACCGGCCTTGCCGCCGTCA
CCGCCGGCGCCGCCGTCCCCGGC	CTTGCCGGCGGTGCCGGCGACCGCGGTGCCGCCGGCG
CCGCCACCACCGCCGTCACCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003417745.1|3767457_3767847_+|DUF732-domain-containing-protein	unknown	unknown	gnl|CDD|368380
NC_021251.1|WP_003417435.1|3718240_3719110_-|inner-membrane-protein-YhjD	unknown	unknown	gnl|CDD|188082
NC_021251.1|WP_031654342.1|3735263_3736244_-|hypothetical-protein	unknown	unknown	gnl|CDD|312941
NC_021251.1|WP_157132559.1|3766837_3767056_-|hypothetical-protein	unknown	unknown	gnl|CDD|366708
NC_021251.1|WP_003417461.1|3725133_3725865_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NC_021251.1|WP_009938650.1|3753675_3753963_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003417738.1|3765692_3766487_-|hypothetical-protein	unknown	unknown	gnl|CDD|369658
NC_021251.1|WP_003417619.1|3741545_3741803_-|DUF3017-domain-containing-protein	unknown	unknown	gnl|CDD|378602
NC_021251.1|WP_003417741.1|3767082_3767343_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_049961743.1|3752157_3752604_+|transposase	unknown	unknown	gnl|CDD|376564
NC_021251.1|WP_003900028.1|3722636_3723986_+|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase	unknown	unknown	gnl|CDD|236105
NC_021251.1|WP_003417452.1|3721124_3722354_-|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl|CDD|236226
NC_021251.1|WP_038438875.1|3725873_3735215_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_021251.1|WP_003900026.1|3717766_3718207_+|heavy-metal-responsive-transcriptional-regulator	unknown	unknown	gnl|CDD|133398
NC_021251.1|WP_003911006.1|3752640_3753381_-|transposase	unknown	unknown	gnl|CDD|376574
NC_021251.1|WP_003417440.1|3719130_3720141_-|tryptophan--tRNA-ligase	unknown	unknown	gnl|CDD|234866
NC_021251.1|WP_009940431.1|3720425_3721058_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|184875
NC_021251.1|WP_003901612.1|3742058_3751532_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_021251.1|WP_003417458.1|3723997_3725137_+|homoserine-O-acetyltransferase	unknown	unknown	gnl|CDD|234678
NC_021251.1|WP_003417739.1|3766568_3766940_-|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223354

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003417745.1|3767457_3767847_+|DUF732-domain-containing-protein	gnl|CDD|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	4.49035e-23
NC_021251.1|WP_003417435.1|3718240_3719110_-|inner-membrane-protein-YhjD	gnl|CDD|188082	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD. This family, including YhjD in E. coli, is a conserved inner membrane protein homologous YihY, which in turn was incorrectly assigned to be ribonuclease BN. This, any suggestion this family is similar to ribonucleases should be removed. [Transcription, Degradation of RNA].	3.67774e-123
NC_021251.1|WP_031654342.1|3735263_3736244_-|hypothetical-protein	gnl|CDD|312941	pfam09606, Med15, ARC105 or Med15 subunit of Mediator complex non-fungal. The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.	0.00133744
NC_021251.1|WP_157132559.1|3766837_3767056_-|hypothetical-protein	gnl|CDD|366708	pfam01565, FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.	3.12703e-05
NC_021251.1|WP_003417461.1|3725133_3725865_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.03104e-26
NC_021251.1|WP_003417738.1|3765692_3766487_-|hypothetical-protein	gnl|CDD|369658	pfam08031, BBE, Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine.	2.38492e-05
NC_021251.1|WP_003417619.1|3741545_3741803_-|DUF3017-domain-containing-protein	gnl|CDD|378602	pfam11222, DUF3017, Protein of unknown function (DUF3017). This bacterial family of proteins with unknown function appear to be restricted to Actinobacteria.	3.92596e-11
NC_021251.1|WP_049961743.1|3752157_3752604_+|transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.45693e-11
NC_021251.1|WP_003900028.1|3722636_3723986_+|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase	gnl|CDD|236105	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated.	0
NC_021251.1|WP_003417452.1|3721124_3722354_-|NADP-dependent-isocitrate-dehydrogenase	gnl|CDD|236226	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase.	0
NC_021251.1|WP_038438875.1|3725873_3735215_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	7.4215e-85
NC_021251.1|WP_003900026.1|3717766_3718207_+|heavy-metal-responsive-transcriptional-regulator	gnl|CDD|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.31191e-56
NC_021251.1|WP_003911006.1|3752640_3753381_-|transposase	gnl|CDD|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.74021e-20
NC_021251.1|WP_003417440.1|3719130_3720141_-|tryptophan--tRNA-ligase	gnl|CDD|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	0
NC_021251.1|WP_009940431.1|3720425_3721058_+|alpha/beta-fold-hydrolase	gnl|CDD|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	1.23792e-15
NC_021251.1|WP_003901612.1|3742058_3751532_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	9.79647e-79
NC_021251.1|WP_003417458.1|3723997_3725137_+|homoserine-O-acetyltransferase	gnl|CDD|234678	PRK00175, metX, homoserine O-acetyltransferase; Provisional.	0
NC_021251.1|WP_003417739.1|3766568_3766940_-|FAD-binding-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	7.3689e-14

Protein sequences

>NC_021251.1|WP_031654342.1|3735263_3736244_-|hypothetical-protein
MLGGKGGDGGNGDHGGPATNPGSGSRGGAGGSGGNGGAGGNATGSGGKGGAGGNGGDGSFGATSGPASIGVTGAPGGNGGKGGAGGSNPNGSGGDGGKGGNGGAGGNGGSIGANSGIVGGSGGAGGAGGAGGNGSLSSGEGGKGGDGGHGGDGVGGNSSVTQGGSGFFGGKGGFGGDGGQGGPNGGGTVGTVAGGGGNGGVGGRGGDGVFAGAGGQGGLGGQGGNGGGSTGGNGGLGGAGGGGGNAPDGGFGGNGGKGGQGGIGGGTQSATGLGGDGGDGGDGGNGGNSGAKAGGAGGKGQAGQPNSGTEPGFGGDGGLGGAGATP
>NC_021251.1|WP_038438875.1|3725873_3735215_-|PPE-family-protein
MSFVVMPPEINSLLIYTGAGPGPLLAAAAAWDELAAELGSAAAAFGSVTSGLVGGIWQGPSSVAMAAAAAPYAGWLSAAAASAESAAGQARAVVGVFEAALAATVDPFVIAANRSRLVSLALSNLFGQNTPAIAAAEFDYELMWAQDVAAMLGYHTGASAAAEALAPFGSPLASLAAAAEPAKSLAVNLGLANVGLFNAGSGNVGSYNVGAGNVGSYNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGEANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGVLWRGDYQGLLGFSSGANVLPVIPLSLDINGGVGAITIEPIHILPDIPININETLYLGPLVVPPINVPAISLGVGIPNISIGPIKINPITLWPAQNFNQTITLAWPVSSITIPQIQQVALSPSPIPTTLIGPIHINTGFSIPVTFSYSTPALTLFPVGLSIPTGGPLTLTLGVTAGTEAFTIPGFSIPEQPLPLAINVIGHINALSTPAITIDNIPLNLHAIGGVGPVDIVGGNVPASPGFGNSTTAPSSGFFNTGAGGVSGFGNVGAHTSGWFNQSTQAMQVLPGTVSGYFNSGTLMSGIGNVGTQLSGMLSGGALGGNNFGLGNIGFDNVGFGNAGSSNFGLANMGIGNIGLANTGNGNIGIGLSGDNLTGFGGFNSGSENVGLFNSGTGNVGFFNSGTGNLGVFNSGSHNTGFFLTGNNINVLAPFTPGTLFTISEIPIDLQVIGGIGPIHVQPIDIPAFDIQITGGFIGIREFTLPEITIPAIPIHVTGTVGLEGFHVNPAFVLFGQTAMAEITADPVVLPDPFITIDHYGPPLGPPGAKFPSGSFYLSISDLQINGPIIGSYGGPGTIPGPFGATFNLSTSSLALFPAGLTVPDQTPVTVNLTGGLDSITLFPGGLAFPENPVVSLTNFSVGTGGFTVFPQGFTVDRIPVDLHTTLSIGPFPFRWDYIPPTPANGPIPAVPGGFGLTSGLFPFHFTLNGGIGPISIPTTTVVDALNPLLTVTGNLEVGPFTVPDIPIPAINFGLDGNVNVSFNAPATTLLSGLGITGSIDISGIQITNIQTQPAQLFMSVGQTLFLFDFRDGIELNPIVIPGSSIPITMAGLSIPLPTVSESIPLNFSFGSPASTVKSMILHEILPIDVSINLEDAVFIPATVLPAIPLNVDVTIPVGPINIPIITEPGSGNSTTTTSDPFSGLAVPGLGVGLLGLFDGSIANNLISGFNSAVGIVGPNVGLSNLGGGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGFGNVGLANSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNIGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIVSTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLDFSFPVGPLIPQTHLVHLRETVNLGPIHIDPIHVHIPPLLDIDQTIDLGSFTVAPITVAPIALDYHETFDLGPLVIFPPMNIPATVIESFSTAPGGPAPPPFVIPATSNVFISTVDFATGNNVIGPFSGALAPTTIQLGASGPSFSVLNLSIPPIHIPGLTIPSVPLRIDVDGGIPGFTLFPDGLTFPKIPVHVDAFAGIPDFTIFPNGYTIDPIPLQLNLDLTLGPVHILIDLPAVPGFGNTTGAPSSGFFNSGAGGVSGFGNVGAMVSGGWNQAPSALLGGGSGVFNAGTLHSGVLNFGSGMSGLFNTSVLGLGAPALVSGLGSVGQQLSGLLASGTALHQGLVLNFGLADVGLGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIVSTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYRPAVLPQTPFLDLTLTGGLGSVVIPAIDIPAIRPEFSANVAIDSFTVPSIPIPQIDLAATTVSVGLGPITVPHLDIPRVPVTLNYLFGSQPGGPLKIGPITGLFNTPIGLTPLALSQIVIGASSSQGTITAFLANLPFSTPVVTIDEIPLLASITGHSEPVDIFPGGLTIPAMNPLSINLSGGTGAVTIPAITIGEIPFDLVAHSTLGPVHILIDLPAVPGFGNTTGAPSSGFFNSGAGGVSGFGNVGAMVSGGWNQAPSALLGGGSGVFNAGTLHSGVLNFGSGMSGLFNTSVLGLGAPALVSGLGSVGQQLSGLLASGTALHQGLVLNFGLADVGLGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIVSTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDTNTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYTSTIIPEFTVANIHASGGAGPIIVPSIQFPAIPLDLSATGHIGGFTIPPVSISPITVRIDPVFDLGPITVQDITIPALGLDPATGVTVGPIFSSGSIIDPFSLTLLGFINVNVPAIQTAPSEILPFTVLLSSLGVTHLTPEITIPGFHIPVDPIHVELPLSVTIGPFVSPEITIPQLPLGLALSGATPAFAFPLEITIDRIPVVLDVNALLGPINAGLVIPPVPGFGNTTAVPSSGFFNIGGGGGLSGFHNLGAGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGADISGVYNTGALGLITSALVSGFGNVGQQLAGLIYTGTGP
>NC_021251.1|WP_003417461.1|3725133_3725865_+|class-I-SAM-dependent-methyltransferase
MTCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAALPQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRVTLPEPFTTVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRATLA
>NC_021251.1|WP_003417458.1|3723997_3725137_+|homoserine-O-acetyltransferase
MTISDVPTQTLPAEGEIGLIDVGSLQLESGAVIDDVCIAVQRWGKLSPARDNVVVVLHALTGDSHITGPAGPGHPTPGWWDGVAGPGAPIDTTRWCAVATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVQADVAALAALGITEVAAVVGGSMGGARALEWVVGYPDRVRAGLLLAVGARATADQIGTQTTQIAAIKADPDWQSGDYHETGRAPDAGLRLARRFAHLTYRGEIELDTRFANHNQGNEDPTAGGRYAVQSYLEHQGDKLLSRFDAGSYVILTEALNSHDVGRGRGGVSAALRACPVPVVVGGITSDRLYPLRLQQELADLLPGCAGLRVVESVYGHDGFLVETEAVGELIRQTLGLADREGACRR
>NC_021251.1|WP_003900028.1|3722636_3723986_+|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase
MSADSNSTDADPTAHWSFETKQIHAGQHPDPTTNARALPIYATTSYTFDDTAHAAALFGLEIPGNIYTRIGNPTTDVVEQRIAALEGGVAALFLSSGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYSLAKLGIEVSFVDDPDDLDTWQAAVRPNTKAFFAETISNPQIDLLDTPAVSEVAHRNGVPLIVDNTIATPYLIQPLAQGADIVVHSATKYLGGHGAAIAGVIVDGGNFDWTQGRFPGFTTPDPSYHGVVFAELGPPAFALKARVQLLRDYGSAASPFNAFLVAQGLETLSLRIERHVANAQRVAEFLAARDDVLSVNYAGLPSSPWHERAKRLAPKGTGAVLSFELAGGIEAGKAFVNALKLHSHVANIGDVRSLVIHPASTTHAQLSPAEQLATGVSPGLVRLAVGIEGIDDILADLELGFAAARRFSADPQSVAAF
>NC_021251.1|WP_003417452.1|3721124_3722354_-|NADP-dependent-isocitrate-dehydrogenase
MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN
>NC_021251.1|WP_009940431.1|3720425_3721058_+|alpha/beta-fold-hydrolase
MLADHVERQLDELGWETSHIVGNSLGGWVAFELERRGRARSVTGIAPAGGWTRWSPVKFEVIAKFIAGAPILAVAHILGQRALRLPFSRLLATLPISATPDGVSERELSGIIDDAAHCPAYFQLLVKALVLPGLQELEHTAVPSHVVLCEQDRVVPPSRFSRHFTDSLPAGHRLTVLDGVGHVPMFEAPGRITELITSFIEECCPHVRAS
>NC_021251.1|WP_003417440.1|3719130_3720141_-|tryptophan--tRNA-ligase
MSTPTGSRRIFSGVQPTSDSLHLGNALGAVAQWVGLQDDHDAFFCVVDLHAITIPQDPEALRRRTLITAAQYLALGIDPGRATIFVQSQVPAHTQLAWVLGCFTGFGQASRMTQFKDKSARQGSEATTVGLFTYPVLQAADVLAYDTELVPVGEDQRQHLELARDVAQRFNSRFPGTLVVPDVLIPKMTAKIYDLQDPTSKMSKSAGTDAGLINLLDDPALSAKKIRSAVTDSERDIRYDPDVKPGVSNLLNIQSAVTGTDIDVLVDGYAGHGYGDLKKDTAEAVVEFVNPIQARVDELTADPAELEAVLAAGAQRAHDVASKTVQRVYDRLGFLL
>NC_021251.1|WP_003417435.1|3718240_3719110_-|inner-membrane-protein-YhjD
MGELAEPGVLDRLRARFGWLDHVVRAFTRFNDRNGSLFAAGLTYYTIFAIFPLLMVGFGVGGFALSRRPELLTTLEERIRTSVSGAVGQQLVDLMNSAIDARASVGVIGLATAAWVGLGWMWHLREALSQMWAHPVAPAGYLRTKLSDLAAMVGTFVVIVATIALTVLGHARPMAAVLRWLEIPQFSVFDEIFRGISVLVSVLVSWVLFTWMIGRLPREPVGLVTAARAGLMAAVGFELFKQVGAIYLQIVLRSPAGAVFGPVLGLMVFAFVTAWLILFATAWAATASA
>NC_021251.1|WP_003900026.1|3717766_3718207_+|heavy-metal-responsive-transcriptional-regulator
MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHDRGEAPCAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWILESDLDEPTAIEVSDIHA
>NC_021251.1|WP_003417619.1|3741545_3741803_-|DUF3017-domain-containing-protein
MTVRAVLRRTVGAQWPILAGVNFWRRGALLIGIGVGVAAVLRLVLSEERAGLLVVRSKGIDFVTTVTVAAAMVYIASTIDPLGTG
>NC_021251.1|WP_003901612.1|3742058_3751532_-|PPE-family-protein
MNFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPYAGWLGSVAAQAVAVAGQARAAVAAFEAALAATVDPAAVAVNRMAMRALAMSNLLGQNAAAIAAVEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLNALFAGPAKMLRLNAGLGNVGNYNVGLGNVGIFNLGAANVGAQNLGAANAGSGNFGFGNIGNANFGFGNSGLGLPPGMGNIGLGNAGSSNYGLANLGVGNIGFANTGSNNIGIGLTGDNLTGIGGLNSGTGNLGLFNSGTGNIGFFNSGTGNFGVFNSGSYNTGVGNAGTASTGLFNVGGFNTGVANVGSYNTGSFNAGNTNTGGFNPGNVNTGWLNTGNTNTGIANSGNVNTGAFISGNFSNGVLWRGDYEGLWGLSGGSTIPAIPIGLELNGGVGPITVLPIQILPTIPLNIHQTFSLGPLVVPDIVIPAFGGGTAIPISVGPITISPITLFPAQNFNTTFPVGPFFGLGVVNISGIEIKDLAGNVTLQLGNLNIDTRINQSFPVTVNWSTPAVTIFPNGISIPNNPLALLASASIGTLGFTIPGFTIPAAPLPLTIDIDGQIDGFSTPPITIDRIPLNLGASVTVGPILINGVNIPATPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGSSGWWNQAQTEVAGAGSGFANFGSLGSGVLNFGSGVSGLYNTGGLPPGTPAVVSGIGNVGEQLSGLSSAGTALNQSLIINLGLADVGSVNVGFGNVGDFNLGAANIGDLNVGLGNVGGGNVGFGNIGDANFGLGNAGLAAGLAGVGNIGLGNAGSGNVGFGNMGVGNIGFGNTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNVGLFNSGTGNFGLFNSGGYNTGIGNGGTGSTGLFNAGNFNTGVANPGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGVANSGTVNTGAFITGNDSNGILWRGNFEGLFGLNVGITIPEFPIHWTSTGGIGPIIIPDTTILPPIHLGLTGQANYGFAVPDIPIPAIHIDFDGAADAGFTAPATTLLSALGITGQFRFGPITVSNVQLNPFNVNLKLQFLHDAFPNEFPDPTISVQIQVAIPLTSATLGGLALPLQQTIDAIELPAISFSQSIPIDIPPIDIPASTINGISMSEVVPIDVSVDIPAVTITGTRIDPIPLNFDVLSSAGPINISIIDIPALPGFGNSTELPSSGFFNTGGGGGSGIANFGAGVSGLLNQASSPMVGTLSGLGNAGSLASGVLNSGVDISGMFNVSTLGSAPAVISGFGNLGNHVSGVSIDGLLAMLTSGGSGGSGQPSIIDAAIAELRHLNPLNIVNLGNVGSYNLGFANVGDVNLGAGNLGNLNLGGGNLGGQNLGLGNLGDGNVGFGNLGHGNVGFGNSGLGALPGIGNIGLGNAGSNNVGFGNMGLGNIGFGNTGTNNLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTGNIGFFNTGTGNWGLFNSGSYNTGIGNSGTGSTGLFNAGSFNTGLANAGSYNTGSLNAGNTNTGGFNPGNVNTGWFNAGHTNTGGFNTGNVNTGAFNSGSFNNGALWTGDHHGLVGFSYSIEITGSTLVDINETLNLGPVHIDQIDIPGMSLFDIHELVNIGPFRIEPIDVPAVVLDIHETMVIPPIVFLPSMTIGGQTYTIPLDTPPAPAPPPFRLPLLFVNALGDNWIVGASNSTGMSGGFVTAPTQGILIHTGPSSATTGSLALTLPTVTIPTITTSPIPLKIDVSGGLPAFTLFPGGLNIPQNAIPLTIDASGVLDPITIFPGGFTIDPLPLSLALNISVPDSSVPIIIVPPTPGFGNATATPSSGFFNSGAGGVSGFGNFGAGSSGWWNQAHAALAGAGSGVLNVGTLNSGVLNVGSGISGLYNTAIVGLGTPALVSGAGNVGQQLSGVLAAGTALTQSPIINLGLADVGNYNLGLGNVGDFNLGAANLGDLNLGLGNIGNANVGFGNIGHGNVGFGNSGLGAALGIGNIGLGNAGSTNVGLANMGVGNIGFANTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNIGFFNSGTGNWGLFNSGSFNTGIGNSGTGSTGLFNAGGFTTGLANAGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGIANSGNVDTGALMSGNFSNGILWRGNYEGLFSYSYSLDVPRITILDAHFTGAFGPVVVPPIPVPAINAHLTGNAAMGAFTIPQIDIPALNPNVTGSVGFGPIAVPSVTIPALTAARAVLDMAASVGATSEIEPFIVWTSSGAIGPTWYSVGRIYNAGDLFVGGNIISGIPTLSTTGPVHAVFNAASQAFNTPALNIHQIPLGFQVPGSIDAITLFPGGLTFPANSLLNLDVFVGTPGATIPAITFPEIPANADGELYVIAGDIPLINIPPTPGIGNTTTVPSSGFFNTGAGGGSGFGNFGANMSGWWNQAHTALAGAGSGIANVGTLHSGVLNLGSGLSGIYNTSTLPLGTPALVSGLGNVGDHLSGLLASNVGQNPITIVNIGLANVGNGNVGLGNIGNLNLGAANIGDVNLGFGNIGDVNLGFGNIGGGNVGFGNIGDANFGFGNSGLAAGLAGMGNIGLGNAGSGNVGWANMGLGNIGFGNTGTNNLGIGLTGDNQSGIGGLNSGTGNIGLFNSGTGNIGFFNSGTANFGLFNSGSYNTGIGNSGVASTGLVNAGGFNTGVANAGSYNTGSFNAGDTNTGGFNPGSTNTGWFNTGNANTGVANAGNVNTGALITGNFSNGILWRGNYEGLAGFSFGYPIPLFPAVGADVTGDIGPATIIPPIHIPSIPLGFAAIGHIGPISIPNIAIPSIHLGIDPTFDVGPITVDPITLTIPGLSLDAAVSEIRMTSGSSSGFKVRPSFSFFAVGPDGMPGGEVSILQPFTVAPINLNPTTLHFPGFTIPTGPIHIGLPLSLTIPGFTIPGGTLIPQLPLGLGLSGGTPPFDLPTVVIDRIPVELHASTTIGPVSLPIFGFGGAPGFGNDTTAPSSGFFNTGGGGGSGFSNSGSGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGTLGLVTSAFVSGFMNVGQQLSGLLFAGTGP
>NC_021251.1|WP_049961743.1|3752157_3752604_+|transposase
MDAAITACHHIAIRDDVGARSIRFSVEPTLAGLRTLTDKLSGYDDIDATVEPTSMTWLPLTIAVENAGDTMHMAGARHCARLRGAIVGKSKSDVIDAEVLTRASEVFDLTPLTLPTPAQLALRRSVIRRAGAVIDANRSWRRLMSLAR
>NC_021251.1|WP_003911006.1|3752640_3753381_-|transposase
MAIDPAAAYASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVTWAFHDRRGRKIDPQWANRRRLLTARERLSDKSFAKMRNRINAVDPRAQILSAWIAKEELRTLLSTVRTGGDPHLARHHLHRFLPGASTRRSPNCSPWPPPLTSHPRSTPSWSPASPTRASVVGEVAEMVGDIDGQCVQVEVPVPERGPAGCGGLDGLGRAGVSATPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR
>NC_021251.1|WP_009938650.1|3753675_3753963_-|hypothetical-protein
MSRRRRRARRAGVVSISVKEYAVTSPKDLPYGEDRIMVRWNKIRWRCREDYCKLGPFTEAITQVPARVRSTLRLRRQMAKAIGDAARSVGRGRPG
>NC_021251.1|WP_003417738.1|3765692_3766487_-|hypothetical-protein
MLASCPARSGAAVADAIKSAVGVQPSGVEHKTLRRMDLVRYLAGGHTTYPPEGFVAGSDVIGTTNPAAAQAIVAAIGTWPPAAGRASALIDSLGGAVGDMDPEGSAFPWCRQSAVVQWYVNTPSDGQVATANKWLSDAHHAVQHFSVGGYVNYLEANAAASQYFGANLSRLTTVRRKYDPDRIMYSGLDFSTRQVAERLLPALGFRVRFGVLVIRCALCTDTVKRLGTLPNLTWSRLKVNVAVTQEQAGVMDLPALPVRRTPRR
>NC_021251.1|WP_003417739.1|3766568_3766940_-|FAD-binding-oxidoreductase
MSAATDLYAVHQALAGESRAIPTGSCPTVGVAGLTLGGGLGADSRHAGLTCDALKSATVVLPGGDAVSASADDHAELFWALRGGGGGNFGVTTSMTFARFPTADCDVVRVDFAPSAAAQVLVG
>NC_021251.1|WP_157132559.1|3766837_3767056_-|hypothetical-protein
MRGGGHSYIGASSANGAMVLDLLGLPGGVHFDSATRNVRCRPRPISMRSIKRWPVRAGRFRPAAARPWVWRV
>NC_021251.1|WP_003417741.1|3767082_3767343_-|hypothetical-protein
MSRQTFLRGAVGAPATSAVFPTILARATPGDGWASLASSIGGQVLLPANGRAFTSGKQIFNSNYSGLNPAAVVTVASQADVRKAVS
>NC_021251.1|WP_003417745.1|3767457_3767847_+|DUF732-domain-containing-protein
MNLRRHQTLTLRLLAASAGILSAAAFAAPAQANPVDDAFIAALNNAGVNYGDPVDAKALGQSVCPILAEPGGSFNTAVASVVARAQGMSQDMAQTFTSIAISMYCPSVMADVASGNLPALPDMPGLPGS

Crispr_ID: NC_021251_11

• CRISPR_ID: NC_021251_11
• CRISPR_location: 3848436-3848525
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021251_11

Consensus_repeat	Method
CCAGGCGTTGGGCTGGCTGCCGAT	CRISPRCasFinder

spacers of NC_021251_11

>11.1|3848460|42|NC_021251|CRISPRCasFinder
GCAGGACATCGACGCCGCCGCGGAGGCCGCGGCCCAGCCAAG

CRISPR arrays and Neighbor proteins around NC_021251_11

CRISPR arrays

The CRISPR arrays of NC_021251_11

>merge|NC_021251|11|3848436-3848525|CRISPRCasFinder
CCAGGCGTTGGGCTGGCTGCCGATGCAGGACATCGACGCCGCCGCGGAGGCCGCGGCCCAGCCAAGCCACGCGTTGGGCTGGCTGCCGAT

>NC_021251|11|7|3848436-3848525|CRISPRCasFinder
CCAGGCGTTGGGCTGGCTGCCGAT	GCAGGACATCGACGCCGCCGCGGAGGCCGCGGCCCAGCCAAG
CCACGCGTTGGGCTGGCTGCCGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003900685.1|3840472_3840703_+|histone-acetyltransferase	unknown	unknown	unknown
NC_021251.1|WP_003418277.1|3853242_3854625_-|glutamate-decarboxylase	unknown	unknown	gnl|CDD|130848
NC_021251.1|WP_003418289.1|3857885_3859760_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl|CDD|234729
NC_021251.1|WP_003902478.1|3849510_3849873_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003901640.1|3856809_3857664_-|DUF4436-domain-containing-protein	unknown	unknown	gnl|CDD|379624
NC_021251.1|WP_003899492.1|3843814_3844699_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
NC_021251.1|WP_003418266.1|3851714_3851870_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003902485.1|3850035_3850572_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_021251.1|WP_003902483.1|3847214_3847514_+|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_021251.1|WP_003418280.1|3854662_3856084_-|NAD(P)H-hydrate-dehydratase	unknown	unknown	gnl|CDD|366541
NC_021251.1|WP_003917789.1|3851894_3852050_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_104591447.1|3844850_3846509_-|IS21-family-transposase	unknown	unknown	gnl|CDD|226950
NC_021251.1|WP_003418141.1|3847599_3848142_+|PPE-family-protein	unknown	unknown	gnl|CDD|227938
NC_021251.1|WP_003418047.1|3839286_3840513_-|alanine-racemase	unknown	unknown	gnl|CDD|234600
NC_021251.1|WP_003900057.1|3859781_3860258_+|DUF2510-domain-containing-protein	unknown	unknown	gnl|CDD|378480
NC_021251.1|WP_003418125.1|3842975_3843731_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224401
NC_021251.1|WP_003902478.1|3840806_3841169_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003418284.1|3856085_3856799_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003418122.1|3842127_3842658_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_021251.1|WP_003908241.1|3846501_3846720_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003418047.1|3839286_3840513_-|alanine-racemase	gnl|CDD|234600	PRK00053, alr, alanine racemase; Reviewed.	2.56905e-175
NC_021251.1|WP_003900057.1|3859781_3860258_+|DUF2510-domain-containing-protein	gnl|CDD|378480	pfam10708, DUF2510, Protein of unknown function (DUF2510). This is family of proteins conserved in Actinobacteria. Many members are annotated as putative membrane proteins but this could not be confirmed.	9.72562e-06
NC_021251.1|WP_003418289.1|3857885_3859760_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_021251.1|WP_003899492.1|3843814_3844699_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	6.96385e-105
NC_021251.1|WP_003418277.1|3853242_3854625_-|glutamate-decarboxylase	gnl|CDD|130848	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha., glutamate decarboxylase. This model represents the pyridoxal phosphate-dependent glutamate (alpha) decarboxylase found in bacteria (low and hi-GC gram positive, proteobacteria and cyanobacteria), plants, fungi and at least one archaon (Methanosarcina). The product of the enzyme is gamma-aminobutyrate (GABA).	0
NC_021251.1|WP_003902483.1|3847214_3847514_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.19277e-08
NC_021251.1|WP_003418280.1|3854662_3856084_-|NAD(P)H-hydrate-dehydratase	gnl|CDD|366541	pfam01256, Carb_kinase, Carbohydrate kinase. This family is related to pfam02110 and pfam00294 implying that it also is a carbohydrate kinase. (personal obs Yeats C).	1.97618e-79
NC_021251.1|WP_104591447.1|3844850_3846509_-|IS21-family-transposase	gnl|CDD|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.10524e-47
NC_021251.1|WP_003418141.1|3847599_3848142_+|PPE-family-protein	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	2.96716e-30
NC_021251.1|WP_003418122.1|3842127_3842658_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.48288e-52
NC_021251.1|WP_003418125.1|3842975_3843731_-|ATP-binding-protein	gnl|CDD|224401	COG1484, DnaC, DNA replication protein [DNA replication, recombination, and repair].	8.96695e-66
NC_021251.1|WP_003901640.1|3856809_3857664_-|DUF4436-domain-containing-protein	gnl|CDD|379624	pfam14494, DUF4436, Domain of unknown function (DUF4436). This is a family of membrane and transmembrane proteins from mycobacterial and related species. The function is not known.	1.83167e-112
NC_021251.1|WP_003902485.1|3850035_3850572_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.05235e-50

Protein sequences

>NC_021251.1|WP_003418141.1|3847599_3848142_+|PPE-family-protein
MPFTLTPAHQISYQMYAGPGADSMRAASQQLRELAFSADTTADSLNDTLFDLDDTWIGGSSAFMTDAALRYLKWLSKHSKRLWQTANTIHHLANTYEDIRQRVVPPAAIEDNREEVRRLIASDITGENAPAIAELDEQYQSYGDTNVQAMNLYAERAQTLLSQLPRWQEPPQIHQRGRGG
>NC_021251.1|WP_003902483.1|3847214_3847514_+|PE-family-protein
MSFIFTTPRALDNAAKSVSGIHDLWLADSKTAITVVNAIVPPAADPVSNRMVGRILEHMAQYQQISSQALEYLRGFSQGLAENAEAYRLAEAQNSTTFD
>NC_021251.1|WP_003908241.1|3846501_3846720_-|hypothetical-protein
MARRSILMLDLVELLTHWHAGRSQVRLSESLGIDRKTVRKYTAPAIAAGIEPGGEPLSAEQWAELIGGWFPE
>NC_021251.1|WP_104591447.1|3844850_3846509_-|IS21-family-transposase
MNDPAARASTWPLIAPHHDRIKDWLDADVTVATIAQRLRDDHGVAASESSVRRWIATHFAEEVARERVTVPRGPVDAGSEAQIDYGRLGMWFDPATARRVAVWAFVMVLAFSRHLFVRPVIRMDQTAWCACHVAAFEFFDGVPARLVCDNLRTGVDKPDLYDPQINRSYAELASHYATLVDPARARKPKDKPRVERPMTYVRDSFWKGREFDSLAQMQQAAVTWSTEVAGLRYLRALEGAQPLRMFEAVEQQALIALPPRAFELTSWSIGTVGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQIFAGNDVVATHVRRPSGRSTDFSHYPPEKIAFHMRTPTWCRHTAELVGPACQQVIAEFMRDNAIHHLRSAQGVLGLRDKHGCDRLEAACARAIEVGDPSYRTIKGILVAGTEHAANEPTTSSPASTAGAFLRGPEQFGTDTPRRLISQRNPEPSREPPRHVRRLQFLERMGSCQVVHRGGTRRSCVSGRCGWSQRSAVSTIRSGQRSVRSPVYLVLAARRRCVSGCARRRSMPAHGPGPRPKNPLS
>NC_021251.1|WP_003899492.1|3843814_3844699_-|IS3-family-transposase
MRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_021251.1|WP_003418125.1|3842975_3843731_-|ATP-binding-protein
MSICDPALRNALRTLKLSGMLDTLDARLAQTRNGDLGHLEFLQALREDEIARRESAALTRRLRRAKFEAQATFEDFDFTANPKLPGAMLRDLAALRWLDAGESVILHGPVGVGKTHVAQALVHAVARRGGDVRFAKTSRMLSDLAGGHADRSWGQRIREYTKPLVLILDDFAMREHTAMHADDLYELISDRAITGKPLILTSNRAPNNWYGLFPNPVVAESLLDRLINTSHQILMDGPSYRPRKRPGRTTS
>NC_021251.1|WP_003418122.1|3842127_3842658_+|PPE-family-protein
MHLMIPAEYISNVIYEGPRADSLYAADQRLRQLADSVRTTAESLNTTLDELHENWKGSSSEWMADAALRYLDWLSKHSRQILRTARVIESLVMAYEETLLRVVPPATIANNREEVRRLIASNVAGVNTPAIADLEAQYEQYRAENIQAMDRYLSWTRFALSKLPRWREPPQIHRSG
>NC_021251.1|WP_003902478.1|3840806_3841169_-|hypothetical-protein
MPNPVTMLYGRKADLVILPHVLAEERPHPYSTPGRKRGAQIALTTGIDALASFAPQIVNPRHGLSRVVQCLGGCENKRHAYFRSISKTPHIRARGAPSVCAVRTVGVDGAKRPPKPIPVQ
>NC_021251.1|WP_003900685.1|3840472_3840703_+|histone-acetyltransferase
MSFGFPTFSQNRFTEQYSGLCPIAPGRGAGLQPCRRDCPVARWLVADHPVFGSDCRCRMMVGVNRVRIGRHELTGA
>NC_021251.1|WP_003418047.1|3839286_3840513_-|alanine-racemase
MKRFWENVGKPNDTTDGRGTTSLAMTPISQTPGLLAEAMVDLGAIEHNVRVLREHAGHAQLMAVVKADGYGHGATRVAQTALGAGAAELGVATVDEALALRADGITAPVLAWLHPPGIDFGPALLADVQVAVSSLRQLDELLHAVRRTGRTATVTVKVDTGLNRNGVGPAQFPAMLTALRQAMAEDAVRLRGLMSHMVYADKPDDSINDVQAQRFTAFLAQAREQGVRFEVAHLSNSSATMARPDLTFDLVRPGIAVYGLSPVPALGDMGLVPAMTVKCAVALVKSIRAGEGVSYGHTWIAPRDTNLALLPIGYADGVFRSLGGRLEVLINGRRCPGVGRICMDQFMVDLGPGPLDVAEGDEAILFGPGIRGEPTAQDWADLVGTIHYEVVTSPRGRITRTYREAENR
>NC_021251.1|WP_003902478.1|3849510_3849873_-|hypothetical-protein
MPNPVTMLYGRKADLVILPHVLAEERPHPYSTPGRKRGAQIALTTGIDALASFAPQIVNPRHGLSRVVQCLGGCENKRHAYFRSISKTPHIRARGAPSVCAVRTVGVDGAKRPPKPIPVQ
>NC_021251.1|WP_003902485.1|3850035_3850572_+|PPE-family-protein
MHPMIPAEYISNIIYEGPGADSLFFAAEQLRLMYNSANMTAKSLTDRLGELQENWKGSSSDLMADAAGRYLDWLTKHSRQILETAYVIDFLAYVYEETRHKVVPPATIANNREEVHRLIASNVAGVNTPAIAGLDAQYQQYRAQNIAVMNDYQSTARFILAYLPRWQEPPQIYGGGGG
>NC_021251.1|WP_003418266.1|3851714_3851870_-|hypothetical-protein
MAALSARRGPKPGKAGANAADAEIAWLRAELDTAREVIRVQGELSALLERL
>NC_021251.1|WP_003917789.1|3851894_3852050_-|hypothetical-protein
MPDPQVPERAQRRTFTVKYKLAILDEYDRADRTERGAILRRENLYSSLLTE
>NC_021251.1|WP_003418277.1|3853242_3854625_-|glutamate-decarboxylase
MSRSHPSVPAHSIAPAYTGRMFTAPVPALRMPDESMDPEAAYRFIHDELMLDGSSRLNLATFVTTWMDPEAEKLMAETFDKNMIDKDEYPATAAIEARCVSMVADLFHAEGLRDHDPTSATGVSTIGSSEAVMLGGLALKWRWRQRVGSWKGRMPNLVMGSNVQVVWEKFCRYFDVEPRYLPMERGRYVITPEQVLAAVDENTIGVVAILGTTYTGELEPIAEICAALDKLAAGGGVDVPVHVDAASGGFVVPFLHPDLVWDFRLPRVVSINVSGHKYGLTYPGVGFVVWRGPEHLPEDLVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRLGRDGYTKVMQALSHTARWLGDQLREVDHCEVISDGSAIPVVSFRLAGDRGYTEFDVSHELRTFGWQVPAYTMPDNATDVAVLRIVVREGLSADLARALHDDAVTALAALDKVKPGGHFDAQHFAH
>NC_021251.1|WP_003418280.1|3854662_3856084_-|NAD(P)H-hydrate-dehydratase
MRHYYSVDTIRAAEAPLLASLPDGALMRRAAFGLATEIGRELTARTGGVVGRRVCAVVGSGDNGGDALWAATFLRRRGAAADAVLLNPDRTHRKALAAFTKSGGRLVESVSAATDLVIDGVVGISGSGPLRPAAAQVFAAVQAAAIPVVAVDIPSGIDVATGAITGPAVHAALTVTFGGLKPVHALADCGRVVLVDIGLDLAHTDVLGFEATDVAARWPVPGPRDDKYTQGVTGVLAGSSTYPGAAVLCTGAAVAATSGMVRYAGTAHAEVLAHWPEVIASPTPAAAGRVQAWVVGPGLGTDEAGAAALWFALDTDLPVLVDADGLTMLADHPDLVAGRNAPTVLTPHAGEFARLAGAPPGDDRVGACRQLADALGATVLLKGNVTVIADPGGPVYLNPAGQSWAATAGSGDVLSGMIGALLASGLPSGEAAAAAAFVHARAAAAAAADPGPGDAPTSASRISGHIRAALAAL
>NC_021251.1|WP_003418284.1|3856085_3856799_-|hypothetical-protein
MADASVVARLRSWALAVWHFVSNAPLTYAWLVVLVITTIIQNNLTGSQLHFVLLHRSTNIAELGRDPLEVLFSSLLWIDGRNLEPYLLLFTLFLAPAEHWLGHLRWLTVGLTAHIGATYLSEGLLYLAIQHRDASERMVHARDIGVSYFLVGVMAVLTYHIAKPWRWGYLGVLLVIFGFPLIAMDKAELDFTAVGHFASILIGLLFYPMARERDGRLWNPARIKSLLHRRGTRGRRA
>NC_021251.1|WP_003901640.1|3856809_3857664_-|DUF4436-domain-containing-protein
MGRILRVVVGLVLVIAAYVTVIALYHSTGLGRPHEVAHGRPTADGTTVTLHVEQLQTIKGVLVANLAVSPGTELLDSQTQGLKDDLTVTVTSVVTPTKRTWSSGSLPGVFPVPLTISGDPANWPFDHYRSGPITVQLYRGAAHAPERVSVTFVDRLPGWNVDISGVGDANVPAPYRVGLHRSPSSVAFGTVIVGVLIALAGVGLFVAVQTARGRRQFQPPMTTWYAAMLFAVIPLRNALPDAPPIGFWIDVTVVLWVVVALVTSMVLYILCWWWHLKPDVDETM
>NC_021251.1|WP_003418289.1|3857885_3859760_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYVGRRPAYVVVMDALRRMEYRGYDSSGIALVDGGTLTVRRRAGRLANLEEAVAEMPSTALSGTTGLGHTRWATHGRPTDRNAHPHRDAAGKIAVVHNGIIENFAVLRRELETAGVEFASDTDTEVAAHLVARAYRHGETADDFVGSVLAVLRRLEGHFTLVFANADDPGTLVAARRSTPLVLGIGDNEMFVGSDVAAFIEHTREAVELGQDQAVVITADGYRISDFDGNDGLQAGRDFRPFHIDWDLAAAEKGGYEYFMLKEIAEQPAAVADTLLGHFVGGRIVLDEQRLSDQELREIDKVFVVACGTAYHSGLLAKYAIEHWTRLPVEVELASEFRYRDPVLDRSTLVVAISQSGETADTLEAVRHAKEQKAKVLAICNTNGSQIPRECDAVLYTRAGPEIGVASTKTFLAQIAANYLLGLALAQARGTKYPDEVEREYHELEAMPDLVARVIAATGPVAELAHRFAQSSTVLFLGRHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEDGLPVIVVMPSPKGSATLHAKLLSNIREIQTRGAVTIVIAEEGDETVRPYADHLIEIPAVSTLLQPLLSTIPLQVFAASVARARGYDVDKPRNLAKSVTVE
>NC_021251.1|WP_003900057.1|3859781_3860258_+|DUF2510-domain-containing-protein
MVGRAVPSPNRRYRRVWPPRTKGQHLSNPYAQHQLKLIRHTGALILWQQRTYVVSGTREQCEAAYKSAQTYNLLVGWWSLVSLLAMNWIALISNFNAIRRVRAAADGASVPHGPHAIAHPAVPRGPIPAGWYPDPSGAGLRYWDGATWTHWTHPPRHR

Crispr_ID: NC_021251_12

• CRISPR_ID: NC_021251_12
• CRISPR_location: 3933770-3934714
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 12 spacers

Consensus repeat of NC_021251_12

Consensus_repeat	Method
GGCGGNNNCGGCGGCNCCGGCGGC	CRT

spacers of NC_021251_12

>12.1|3933794|45|NC_021251|CRT
GACGCCCCCGCCAGCACAGGTCTAACCGGTGGTACCGGGTTCGCT
>12.2|3933863|57|NC_021251|CRT
CAGGGCGGCAACGCCATTGCCGGCGGCATCAACGGCTCCGGTGGTGCCGGCGGCACC
>12.3|3933944|63|NC_021251|CRT
ATGGGTGGCTCCGGTGCTGATAATGCCAGCGGGATTGGCGCCGACGGCGGCGCGGGTGGGACT
>12.4|3934031|75|NC_021251|CRT
GCCGGCGGGGCCGCCGGCACCGGAGGAACCGGCGGGGTTGTCGGCGCCGCGGGCAAGGCCGGTATCGGCGGCACC
>12.5|3934130|69|NC_021251|CRT
GCGGGCAGCGCCGGCACGGATGCGACCGCTACCGGTGCCACCGGCGGCACCGGGTTTTCCGGTGGAGCC
>12.6|3934223|39|NC_021251|CRT
AACACCGGGGTTGGCGGCACCAACGGCTCCGGCGGGCAA
>12.7|3934286|45|NC_021251|CRT
GCCGGTGGTGCTGGCGGTGTCGGCGCCGACAACCCCACCGGCATC
>12.8|3934355|51|NC_021251|CRT
AAAGGCGGCGCCGGCGGCGCGGGTGGCGCCGGCGCGGACGCGACCGCTACC
>12.9|3934430|39|NC_021251|CRT
GCCGGTGGCGCCGGCGGGGCCGGCGGGCAGGGCGGTAGC
>12.10|3934493|72|NC_021251|CRT
TCTGGTGGCGCTGGCGGCACCGGCGGACAAGGCGGCGCCGGGGGCGCTGGCGGGGCCGGCGCCGATAACCCC
>12.11|3934589|48|NC_021251|CRT
ACCGGCGGCACCGGCGGAGCGGCCGGAGCCGGCGGGGCCGGTGGCGCC
>12.12|3934661|30|NC_021251|CRT
GCGGTGGGCAGCGTCGGTAACGCCGGGATC

CRISPR arrays and Neighbor proteins around NC_021251_12

CRISPR arrays

The CRISPR arrays of NC_021251_12

>merge|NC_021251|12|3933770-3934714|CRT
GGCGGTGCCGGAGCGGCCGGCGCCGACGCCCCCGCCAGCACAGGTCTAACCGGTGGTACCGGGTTCGCTGGCGGGGCCGGCGGCGTCGGCGGCCAGGGCGGCAACGCCATTGCCGGCGGCATCAACGGCTCCGGTGGTGCCGGCGGCACCGGCGGCCAAGGCGGCGCCGGCGGCATGGGTGGCTCCGGTGCTGATAATGCCAGCGGGATTGGCGCCGACGGCGGCGCGGGTGGGACTGGCGGTAACGCCGGCGCCGGCGGGGCCGGCGGGGCCGCCGGCACCGGAGGAACCGGCGGGGTTGTCGGCGCCGCGGGCAAGGCCGGTATCGGCGGCACCGGCGGCCAAGGCGGCGCCGGCGGCGCGGGCAGCGCCGGCACGGATGCGACCGCTACCGGTGCCACCGGCGGCACCGGGTTTTCCGGTGGAGCCGGCGGGGCCGGCGGGGCCGGCGGCAACACCGGGGTTGGCGGCACCAACGGCTCCGGCGGGCAAGGCGGCACCGGCGGCGCGGGCGGCGCCGGTGGTGCTGGCGGTGTCGGCGCCGACAACCCCACCGGCATCGGCGGCACCGGCGGCACCGGCGGGAAAGGCGGCGCCGGCGGCGCGGGTGGCGCCGGCGCGGACGCGACCGCTACCGGCGCCACCGGCGGCACCGGGTTCGCCGGTGGCGCCGGCGGGGCCGGCGGGCAGGGCGGTAGCAGCGGTGCCGGCGGCACCAACGGCTCTGGTGGCGCTGGCGGCACCGGCGGACAAGGCGGCGCCGGGGGCGCTGGCGGGGCCGGCGCCGATAACCCCACCGGCATCGGCGGCGCCGGCGGCACCGGCGGCACCGGCGGAGCGGCCGGAGCCGGCGGGGCCGGTGGCGCCATCGGTACCGGCGGCACCGGCGGCGCGGTGGGCAGCGTCGGTAACGCCGGGATCGGCGGTACCGGCGGTACGGGTGGT

>NC_021251|12|5|3933770-3934714|CRT
GGCGGTGCCGGAGCGGCCGGCGCC	GACGCCCCCGCCAGCACAGGTCTAACCGGTGGTACCGGGTTCGCT
GGCGGGGCCGGCGGCGTCGGCGGC	CAGGGCGGCAACGCCATTGCCGGCGGCATCAACGGCTCCGGTGGTGCCGGCGGCACC
GGCGGCCAAGGCGGCGCCGGCGGC	ATGGGTGGCTCCGGTGCTGATAATGCCAGCGGGATTGGCGCCGACGGCGGCGCGGGTGGGACT
GGCGGTAACGCCGGCGCCGGCGGG	GCCGGCGGGGCCGCCGGCACCGGAGGAACCGGCGGGGTTGTCGGCGCCGCGGGCAAGGCCGGTATCGGCGGCACC
GGCGGCCAAGGCGGCGCCGGCGGC	GCGGGCAGCGCCGGCACGGATGCGACCGCTACCGGTGCCACCGGCGGCACCGGGTTTTCCGGTGGAGCC
GGCGGGGCCGGCGGGGCCGGCGGC	AACACCGGGGTTGGCGGCACCAACGGCTCCGGCGGGCAA
GGCGGCACCGGCGGCGCGGGCGGC	GCCGGTGGTGCTGGCGGTGTCGGCGCCGACAACCCCACCGGCATC
GGCGGCACCGGCGGCACCGGCGGG	AAAGGCGGCGCCGGCGGCGCGGGTGGCGCCGGCGCGGACGCGACCGCTACC
GGCGCCACCGGCGGCACCGGGTTC	GCCGGTGGCGCCGGCGGGGCCGGCGGGCAGGGCGGTAGC
AGCGGTGCCGGCGGCACCAACGGC	TCTGGTGGCGCTGGCGGCACCGGCGGACAAGGCGGCGCCGGGGGCGCTGGCGGGGCCGGCGCCGATAACCCC
ACCGGCATCGGCGGCGCCGGCGGC	ACCGGCGGCACCGGCGGAGCGGCCGGAGCCGGCGGGGCCGGTGGCGCC
ATCGGTACCGGCGGCACCGGCGGC	GCGGTGGGCAGCGTCGGTAACGCCGGGATC
GGCGGTACCGGCGGTACGGGTGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003419184.1|3955530_3956370_+|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003419179.1|3954643_3955435_+|crotonase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|181122
NC_021251.1|WP_003900084.1|3958424_3959468_-|LLM-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274647
NC_021251.1|WP_003418993.1|3923633_3923825_-|ferredoxin	unknown	unknown	gnl|CDD|224064
NC_021251.1|WP_003906120.1|3917451_3918525_-|virulence-factor-Mce-family-protein	unknown	unknown	gnl|CDD|273384
NC_021251.1|WP_014585416.1|3919566_3920769_-|virulence-factor-Mce4A	unknown	unknown	gnl|CDD|273384
NC_021251.1|WP_003900082.1|3956424_3957621_-|steroid-C26-monooxygenase-Cyp142	unknown	unknown	gnl|CDD|225035
NC_021251.1|WP_003901655.1|3926458_3927967_+|AMP-binding-protein	unknown	unknown	gnl|CDD|236120
NC_021251.1|WP_003418983.1|3920788_3921631_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223838
NC_021251.1|WP_003902513.1|3946985_3947642_-|fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|236100
NC_021251.1|WP_003419190.1|3957649_3958360_+|acetoacetate-decarboxylase-family-protein	unknown	unknown	gnl|CDD|377649
NC_021251.1|WP_003418997.1|3924039_3925242_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
NC_021251.1|WP_003901661.1|3959620_3960532_+|DNA-binding-protein	unknown	unknown	gnl|CDD|224462
NC_021251.1|WP_003418990.1|3922655_3923609_-|3-oxoacyl-ACP-reductase	unknown	unknown	gnl|CDD|181120
NC_021251.1|WP_003418972.1|3918514_3919567_-|virulence-factor-Mce-family-protein	unknown	unknown	gnl|CDD|273384
NC_021251.1|WP_003419000.1|3925266_3926388_+|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl|CDD|224871
NC_021251.1|WP_003911024.1|3952923_3954570_-|acyl-CoA-synthetase	unknown	unknown	gnl|CDD|236100
NC_021251.1|WP_003421145.1|3939154_3939991_-|amidohydrolase	unknown	unknown	gnl|CDD|225070
NC_021251.1|WP_014585422.1|3937610_3939158_-|acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|236063
NC_021251.1|WP_003418986.1|3921665_3922430_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223838

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003419179.1|3954643_3955435_+|crotonase/enoyl-CoA-hydratase-family-protein	gnl|CDD|181122	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein.	0
NC_021251.1|WP_003900084.1|3958424_3959468_-|LLM-class-F420-dependent-oxidoreductase	gnl|CDD|274647	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family. Members of this protein family are predicted to be oxidoreductases dependent on coenzyme F420. The family includes a single member in Mycobacterium tuberculosis (Rv3520c/MT3621) but four in Mycobacterium smegmatis. Prediction that this family is F420-dependent is based primarily on Partial Phylogenetic Profiling vs. F420 biosynthesis. [Unknown function, Enzymes of unknown specificity].	0
NC_021251.1|WP_003418993.1|3923633_3923825_-|ferredoxin	gnl|CDD|224064	COG1141, Fer, Ferredoxin [Energy production and conversion].	6.5974e-14
NC_021251.1|WP_003906120.1|3917451_3918525_-|virulence-factor-Mce-family-protein	gnl|CDD|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	1.64892e-87
NC_021251.1|WP_014585416.1|3919566_3920769_-|virulence-factor-Mce4A	gnl|CDD|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	6.83768e-85
NC_021251.1|WP_003900082.1|3956424_3957621_-|steroid-C26-monooxygenase-Cyp142	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.72638e-107
NC_021251.1|WP_003901655.1|3926458_3927967_+|AMP-binding-protein	gnl|CDD|236120	PRK07867, PRK07867, acyl-CoA synthetase; Validated.	0
NC_021251.1|WP_003418983.1|3920788_3921631_-|ABC-transporter-permease	gnl|CDD|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	9.90895e-74
NC_021251.1|WP_003902513.1|3946985_3947642_-|fatty-acid--CoA-ligase	gnl|CDD|236100	PRK07798, PRK07798, acyl-CoA synthetase; Validated.	8.05622e-104
NC_021251.1|WP_003419190.1|3957649_3958360_+|acetoacetate-decarboxylase-family-protein	gnl|CDD|377649	pfam06314, ADC, Acetoacetate decarboxylase (ADC). This family consists of several acetoacetate decarboxylase (ADC) proteins (EC:4.1.1.4).	8.3862e-27
NC_021251.1|WP_003418997.1|3924039_3925242_+|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	4.72908e-173
NC_021251.1|WP_003901661.1|3959620_3960532_+|DNA-binding-protein	gnl|CDD|224462	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only].	9.89177e-41
NC_021251.1|WP_003418990.1|3922655_3923609_-|3-oxoacyl-ACP-reductase	gnl|CDD|181120	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	2.1253e-180
NC_021251.1|WP_003418972.1|3918514_3919567_-|virulence-factor-Mce-family-protein	gnl|CDD|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	6.61137e-85
NC_021251.1|WP_003419000.1|3925266_3926388_+|acyl-CoA/acyl-ACP-dehydrogenase	gnl|CDD|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.51968e-48
NC_021251.1|WP_003911024.1|3952923_3954570_-|acyl-CoA-synthetase	gnl|CDD|236100	PRK07798, PRK07798, acyl-CoA synthetase; Validated.	0
NC_021251.1|WP_003421145.1|3939154_3939991_-|amidohydrolase	gnl|CDD|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	2.24025e-81
NC_021251.1|WP_014585422.1|3937610_3939158_-|acetolactate-synthase-large-subunit	gnl|CDD|236063	PRK07586, PRK07586, acetolactate synthase large subunit.	0
NC_021251.1|WP_003418986.1|3921665_3922430_-|ABC-transporter-permease	gnl|CDD|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	5.65389e-88

Protein sequences

>NC_021251.1|WP_003901655.1|3926458_3927967_+|AMP-binding-protein
MTPTHPTVTELLLPLSEIDDRGVYFEDSFTSWRDHIRHGAAIAAALRERLDPARPPHVGVLLQNTPFFSATLVAGALSGIVPVGLNPVRRGAALAGDIAKADCQLVLTGSGSAEVPADVEHINVDSPEWTDEVAAHRDTEVRFRSADLADLFMLIFTSGTSGDPKAVKCSHRKVAIAGVTITQRFSLGRDDVCYVSMPLFHSNAVLVGWAVAAACQGSMALRRKFSASQFLADVRRYGATYANYVGKPLSYVLATPELPDDADNPLRAVYGNEGVPGDIDRFGRRFGCVVMDGFGSTEGGVAITRTLDTPAGALGPLPGGIQIVDPDTGEPCPTGVVGELVNTAGPGGFEGYYNDEAAEAERMAGGVYHSGDLAYRDDAGYAYFAGRLGDWMRVDGENLGTAPIERVLMRYPDATEVAVYPVPDPVVGDQVMAALVLAPGTKFDADKFRAFLTEQPDLGHKQWPSYVRVSAGLPRTMTFKVIKRQLSAEGVACADPVWPIRR
>NC_021251.1|WP_003419000.1|3925266_3926388_+|acyl-CoA/acyl-ACP-dehydrogenase
MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPESLGGDGFGVLEQVAVLVALGHQLAAVPYLESVVLAAGALARFGSPELQQGWGVSAVSGDRILTVALDGEMGEGPVQAAGTGHGYRLTGTRTQVGYGPVADAFLVPAETDSGAAVFLVAAGDPGVAVTALATTGLGSVGHLELNGAKVDAARRVGGTDVAVWLGTLSTLSRTAFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQLRRIGRELAETPA
>NC_021251.1|WP_003418997.1|3924039_3925242_+|acyl-CoA-dehydrogenase
MRISYTPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRETIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAGAPVPFLTINSVAPTIMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDLANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGAKKHRGISVLIVPTTAEGFSWTPVHTMAGPDTSATYYSDVRVPVANRVGEENAGWKLVTNQLNHERVALVSPAPIFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLARVHAKAEVLKLINWELASSQSGPKDAGPSPADASAAKVFGTELATEAYRLLMEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGMVALGLPRANR
>NC_021251.1|WP_003418993.1|3923633_3923825_-|ferredoxin
MRVIVDRDRCEGNAVCLGIAPDIFDLDDEDYAVVKTDPIPVDQEDLAEQAIAECPRAALSRGE
>NC_021251.1|WP_003418990.1|3922655_3923609_-|3-oxoacyl-ACP-reductase
MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALDASDVVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVGLGGLDIVVNNAGITRDRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAEGGSVFGRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAARALGRYGVCANVICPRARTAMTADVFGAAPDVEAGQIDPLSPQHVVSLVQFLASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLRDYFAGRDPEQSFSATDLMRQ
>NC_021251.1|WP_003418986.1|3921665_3922430_-|ABC-transporter-permease
MIQQLAVPARAVGGFFEMSMDTARAAFRRPFQFREFLDQTWMVARVSLVPTLLVSIPFTVLVAFTLNILLREIGAADLSGAGTAFGTITQLGPVVTVLVVAGAGATAICADLGARTIREEIDAMRVLGIDPIQRLVVPRVLASTLVALLLNGLVCAIGLSGGYAFSVFLQGVNPGAFINGLTVLTGLRELILAEIKALLFGVMAGLVGCYRGLTVKGGPKGVGNAVNETVVYAFICLFVINVVMTAIGVRISAQ
>NC_021251.1|WP_003418983.1|3920788_3921631_-|ABC-transporter-permease
MSYDVTIRFRRFFSRLQRPVDNFGEQALFYGETMRYVPNAITRYRKETVRLVAEMTLGAGALVMIGGTVGVAAFLTLASGGVIAVQGYSSLGDIGIEALTGFLSAFLNVRVVAPVIAGIALAATIGAGATAQLGAMRVSEEIDAVECMAVHSVSYLVSTRLIAGLVAIIPLYSLSVLAAFFAARFTTVFVNGQSAGLYDHYFNTFLIPSDLLWSFMQAIAMSIAVMLVHTYYGYNASGGSVGVGVAVGQAVRTSLIVVVVITLFISLAVYGASGNFNLSG
>NC_021251.1|WP_014585416.1|3919566_3920769_-|virulence-factor-Mce4A
MSGGGSRRTSVRVAAALLAGLMVGSAVLTYLSYTAAFTSTDTVTVSSPRAGLVMEKGAKVKYRGIQVGKVTDISYSGNQARLKLSIDSGEMGFIPSNATVRIAGNTIFGAKSVEFIPPKTPSPKPLSPNAHVAASQVQLEVNTLFQSLIDLLHKIDPLETNATLSALSEGLRGHGDDLGALLSGLNTLTRQANPKLPALQEDFRKAAVVANVYADAAGDLNTVFDNLPTINKTIVDQKDNLNDTLLATIGLSNNAYETLAPAEQNFIDAINRLRAPLKVTSDYSPVFGCLFKGIARGVKEFAPLIGVRKAGLFTSSSFVLGAPSYTYPESLPIVNASGGPNCRGLPDIPTKQTGGSFYRAPFLVTDNALIPYQPFTELQVDAPSTLQFLFNGAFAERDDF
>NC_021251.1|WP_003418972.1|3918514_3919567_-|virulence-factor-Mce-family-protein
MAGSGVPSHRSMVIKVSVFAVVMLLVAAGLVVVFGDFRFGPTTVYHATFTDASRLKAGQKVRIAGVPVGSVKAVKLNPDHSIDVAFAIDRSYTLYSSTRAVIRYENLVGDRFLEITSGPGELRKLPPGGTINVAHTQPALDLDALLGGLRPVLKGFDADKINTITSAVIELLQGQGGPLANVLADTGAFSAALGARDQLIGEVITNLNAVLATVDAKSAQFSASVDQLQQLVSGLAKNRDPIAGAISPLASTTTDLTELLRNSRRPLQGILENARPLATELDNRKAEVNNDIEQLGEDYLRLSALGSYGAFFNIYFCSVTIKINGPAGSDILLPIGGQPDPSKGRCAFAK
>NC_021251.1|WP_003906120.1|3917451_3918525_-|virulence-factor-Mce-family-protein
MLNRKPSSKHERDPLRTGIFGLVLVICVVLIAFGYSGLPFWPQGKTYDAYFTDAGGITPGNSVYVSGLKVGAVSAVSLAGNSAKVTFSVDRSIVVGDQSLAAIRTDTILGERSIAVSPAGSGKSTTIPLSRTTTPYTLNGVLQDLGRNANDLNRPQFEQALNVFTQALHDATPQVRGAVDGLTSLSRALNSRDEALQGLLAHAKSVTSVLSERAEQVNKLVEDGNQLFAALDARRAALSALISGIDDVAAQISGFVADNRKEFGPALSKLNLVLANLNERRDYITEALKRLPTYATTLGEVVGSGPGFNVNVYSVLPGPLVATVFDLVFQPGKLPDSLADYLRGFIQERWIIRPKSP
>NC_021251.1|WP_014585422.1|3937610_3939158_-|acetolactate-synthase-large-subunit
MNGAQALINTLVDGGVDVCFANPGTSEMHFVAALDAVPRMRGMLTLFEGVATGAADGYARIAGRPAAVLLHLGPGLGNGLANLHNARRARVPMVVVVGDHATYHKKYDAPLESDIDAVAGTVSGWVRRTEAAADVGADAEAAIAASRSGSQIATLILPADVCWSDGAHAAAGVPAQAAAAPVDVGPVAGVLRSGEPAMMLIGGDATRGPGLTAAARIVQATGARWLCETFPTCLERGAGIPAVERLAYFAEGAAAQLDGVKHLVLAGARSPVSFFAYPGMPSDLVPAGCEVHVLAEPGGAADALAALADEVAPGTVAPVAGASRPQLPTGDLTSVSAADVVGALLPERVIVVDESNTCGVLLPQATAGAPAHDWLTLTGGAIGYGIPAAVGAAVAAPDRPVLCLESDGSAMYTISGLWSQARENLDVTTVIYNNGAYDILRIELQRVGAGSDPGPKALDLLDISRPTMDFVKIAEGMGVPARRVTTCEEFADALRAAFAEPGPHLIDVVVPSLVG
>NC_021251.1|WP_003421145.1|3939154_3939991_-|amidohydrolase
MTIDVWMQHPTQRFLHGDMFASLRRWTGGSIPETDIPIEATVSSMDAGGVTLGLLSAWRGPNGQDLISNDAVAEWVRLYPNRFAGLAAVDLDRPMAAVRELRRRVGEGFVGLRVVPWLWGAPPTDRRYYPLFAECVQSAVPFCTQVGHTGPLRPSETGRPIPYIDQVALDFPELVIVCGHVGYPWTEEMVAVARKHENVYIDTSAYTIKRLPGKLVRFMKTDTGQRKVLFGTNYPMIAHTHALTGLDELGLSDEARRDFLHGNAVRVFKLDPRGKVQT
>NC_021251.1|WP_003902513.1|3946985_3947642_-|fatty-acid--CoA-ligase
MAASLSENLSCHSSNMCRLSGNAATNLERPGEEPPGDRCTRRQAVRPARTLAKKGNIPVGYYKDEKKTAETFRTINGVRYAIPGDYAQVEEDGTVTMLGRGSVSINSGGEKVYPEEVEAALKGHPDVFDALVVGVPDPRYGQQVAAVVQARPGCRPSLAELDSFVRSEIAGYKVPRSLWFVDEVKRSPAGKPDYRWAKEQTEARPADDVHAGHVTSGS
>NC_021251.1|WP_003911024.1|3952923_3954570_-|acyl-CoA-synthetase
MAVALNIADLAEHAIDAVPDRVAVICGDEQLTYAQLEDKANRLAHHLIDQGVQKYDKVGLYCRNRIEIVIAMLGIVKAGAILVNVNFRYVEGELRYLFDNSDMVALVHERRYADRVANVLPDTPHVRTILVVEDGSDQDYRRYGGVEFYSAIAAGSPERDFGERSADAIYLLYTGGTTGFPKGVMWRHEDIYRVLFGGTDFATGEFVKDEYDLAKAAAANPPMIRYPIPPMIHGATQSATWMALFSGQTTVLAPEFNADEVWRTIHKHKVNLLFFTGDAMARPLVDALVKGNDYDLSSLFLLASTAALFSPSIKEKLLELLPNRVITDSIGSSETGFGGTSVVAAGQAHGGGPRVRIDHRTVVLDDDGNEVKPGSGMRGVIAKKGNIPVGYYKDEKKTAETFRTINGVRYAIPGDYAQVEEDGTVTMLGRGSVSINSGGEKVYPEEVEAALKGHPDVFDALVVGVPDPRYGQQVAAVVQARPGCRPSLAELDSFVRSEIAGYKVPRSLWFVDEVKRSPAGKPDYRWAKEQTEARPADDVHAGHVTSGG
>NC_021251.1|WP_003419179.1|3954643_3955435_+|crotonase/enoyl-CoA-hydratase-family-protein
MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPPGDSFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEAKEMGLIGHVVPDGQALTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
>NC_021251.1|WP_003419184.1|3955530_3956370_+|hypothetical-protein
MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADLTAWSRAQAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPAGIHTWSDRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALARATDLKLADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIRAGFPRPQTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNKDIKRAEALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT
>NC_021251.1|WP_003900082.1|3956424_3957621_-|steroid-C26-monooxygenase-Cyp142
MTEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFSNAGGIRPDQPALPMMIDMDDPAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCERGECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSDDLVTFLSSHVSQEDFQITMDAFAAYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLSGGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEKMMLLFESANFDEAVFCEPEKFDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG
>NC_021251.1|WP_003419190.1|3957649_3958360_+|acetoacetate-decarboxylase-family-protein
MPVSQHTIAGTVLTMPVRIRTANLHSAMFSVPADPAQRLIDYSGLRVCEYLPGKAIVMQMLVRYVDGDLGRYHEYGTAIMVNPPGTQRRGPRALTRAAAFIHHLPVDQVFTLEAGRTIWGFPKIMADFNVTDGRRFGFDVSADGRLIAGIEFSTGLPVPTLGWQMLKTYSHHDGVTREIPWEMKVSGLRARLGGARLRLGDHPYAKELASLGLPKRALLSQSAANVEMTFGDGHPI
>NC_021251.1|WP_003900084.1|3958424_3959468_-|LLM-class-F420-dependent-oxidoreductase
MEAGMKLGLQLGYWGAQPPQNHAELVAAAEDAGFDTVFTAEAWGSDAYTPLAWWGSSTQRVRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQRFPKPLARTREYIDIVRQVWARESPVTSAGPHYRLPLTGEGTTGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIFYSPRMAGMYNEWLDEGFARPGARRSREDFEICATAQVVITDDRAAAFAGIKPFLALYMGGMGAEETNFHADVYRRMGYTQVVDEVTKLFRSGRKDEAAEIIPDELVDDAVIVGDIDHVRKQMAVWEAAGVTMMVVTAGSAEQVRDLAALV
>NC_021251.1|WP_003901661.1|3959620_3960532_+|DNA-binding-protein
MGPTLSRFFTALRARRIVGVRGSDGRVHVPPVEYDPVTYEPLSEMVPVSSVGTVASWTWQPEPLAGQPLDRPFAWALIKLDGADTLLMHAVDVGTAGPSAIHTGARVHAHWADQPVGAITDIACFALGETAEPVAAHKTEDARDPVTMIVTPIQLEIQHTASHEESAYLRAIAQGKLVGARTGKTGKVYFPPHGADPATGKPTSEFVELPDKGTVTTFAIVNIPFLGQRIKPPYVAAYVLLDGADIPFLHLVSDVDAHQVRMGMRVEAVWKPRERWGLGIDNIEYFRPTGEPDADYDTYKHHL

Crispr_ID: NC_021251_13

• CRISPR_ID: NC_021251_13
• CRISPR_location: 4113016-4113104
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021251_13

Consensus_repeat	Method
GCTCGGCGACGATGCGGGCCGGATGACGGCC	CRISPRCasFinder

spacers of NC_021251_13

>13.1|4113047|27|NC_021251|CRISPRCasFinder
CGAGGAGGAGCCGAGCAATCGAACCGA

CRISPR arrays and Neighbor proteins around NC_021251_13

CRISPR arrays

The CRISPR arrays of NC_021251_13

>merge|NC_021251|13|4113016-4113104|CRISPRCasFinder
GCTCGGCGACGATGCGGGCCGGATGACGGCCCGAGGAGGAGCCGAGCAATCGAACCGAGCTCGGCGACGATGCGGGCCGGATGACGGCC

>NC_021251|13|8|4113016-4113104|CRISPRCasFinder
GCTCGGCGACGATGCGGGCCGGATGACGGCC	CGAGGAGGAGCCGAGCAATCGAACCGA
GCTCGGCGACGATGCGGGCCGGATGACGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021251.1|WP_003899624.1|4099273_4100437_-|TadA-family-conjugal-transfer-associated-ATPase	unknown	unknown	gnl|CDD|200328
NC_021251.1|WP_003419733.1|4120396_4120852_-|RidA-family-protein	unknown	unknown	gnl|CDD|100006
NC_021251.1|WP_003906177.1|4118815_4119490_+|cAMP-activated-global-transcriptional-regulator-CRP	unknown	unknown	gnl|CDD|223736
NC_021251.1|WP_003900733.1|4104369_4106016_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NC_021251.1|WP_003899631.1|4110129_4112085_+|acetate--CoA-ligase	unknown	unknown	gnl|CDD|234677
NC_021251.1|WP_003901692.1|4107796_4109422_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173853
NC_021251.1|WP_003419701.1|4106868_4107795_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_021251.1|WP_003902541.1|4117494_4118232_-|endonuclease-III	unknown	unknown	gnl|CDD|223255
NC_021251.1|WP_003419708.1|4112120_4112819_-|protease	unknown	unknown	unknown
NC_021251.1|WP_003899635.1|4118339_4118717_+|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003899626.1|4103602_4104373_-|hypothetical-protein	unknown	unknown	unknown
NC_021251.1|WP_003899628.1|4106012_4106876_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_021251.1|WP_003419721.1|4116811_4117495_-|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NC_021251.1|WP_003419712.1|4113683_4114667_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_021251.1|WP_003419731.1|4119595_4120390_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293836
NC_021251.1|WP_003419718.1|4115858_4116680_-|CoA-pyrophosphatase	unknown	unknown	gnl|CDD|239518
NC_021251.1|WP_003419714.1|4114659_4115853_-|acid-resistance-serine-protease-MarP	unknown	unknown	gnl|CDD|379142
NC_021251.1|WP_003419710.1|4113164_4113683_+|phage-holin-family-protein	unknown	unknown	gnl|CDD|377816
NC_021251.1|WP_003900732.1|4100433_4101486_-|septum-site-determining-protein-Ssd	unknown	unknown	gnl|CDD|274798
NC_021251.1|WP_003419689.1|4101984_4102848_+|HAD-IB-family-hydrolase	unknown	unknown	gnl|CDD|273654

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021251.1|WP_003899624.1|4099273_4100437_-|TadA-family-conjugal-transfer-associated-ATPase	gnl|CDD|200328	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase. Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.	1.05849e-164
NC_021251.1|WP_003419733.1|4120396_4120852_-|RidA-family-protein	gnl|CDD|100006	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	7.62827e-68
NC_021251.1|WP_003906177.1|4118815_4119490_+|cAMP-activated-global-transcriptional-regulator-CRP	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	3.59113e-55
NC_021251.1|WP_003900733.1|4104369_4106016_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_021251.1|WP_003899631.1|4110129_4112085_+|acetate--CoA-ligase	gnl|CDD|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0
NC_021251.1|WP_003901692.1|4107796_4109422_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	4.27273e-122
NC_021251.1|WP_003419701.1|4106868_4107795_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.57934e-99
NC_021251.1|WP_003902541.1|4117494_4118232_-|endonuclease-III	gnl|CDD|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	3.2984e-106
NC_021251.1|WP_003899628.1|4106012_4106876_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.77559e-81
NC_021251.1|WP_003419721.1|4116811_4117495_-|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.72736e-22
NC_021251.1|WP_003419712.1|4113683_4114667_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.34553e-25
NC_021251.1|WP_003419731.1|4119595_4120390_-|MBL-fold-metallo-hydrolase	gnl|CDD|293836	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	3.29322e-75
NC_021251.1|WP_003419718.1|4115858_4116680_-|CoA-pyrophosphatase	gnl|CDD|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	1.20605e-47
NC_021251.1|WP_003419689.1|4101984_4102848_+|HAD-IB-family-hydrolase	gnl|CDD|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	5.37865e-86
NC_021251.1|WP_003419710.1|4113164_4113683_+|phage-holin-family-protein	gnl|CDD|377816	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III. Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.	8.41555e-32
NC_021251.1|WP_003900732.1|4100433_4101486_-|septum-site-determining-protein-Ssd	gnl|CDD|274798	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein. Members of this protein family belong to the MinD/ParA family of P-loop NTPases, and in particular show homology to the CpaE family of pilus assembly proteins (see ). Nearly all members are found, not only in a gene context consistent with pilus biogenesis or a pilus-like secretion apparatus, but also near a DEAD/DEAH-box helicase, suggesting an involvement in DNA transfer activity. The model describes a clade restricted to the Actinobacteria.	4.37512e-92
NC_021251.1|WP_003419714.1|4114659_4115853_-|acid-resistance-serine-protease-MarP	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	2.19977e-19

Protein sequences

>NC_021251.1|WP_003419708.1|4112120_4112819_-|protease
MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGDTMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGNDGLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCGVTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCITKYIPLHTPAVVMSINADLADINAKNRPGAGFVPVPA
>NC_021251.1|WP_003899631.1|4110129_4112085_+|acetate--CoA-ligase
MSESTPEVSSSYPPPAHFAEHANARAELYREAEEDRLAFWAKQANRLSWTTPFTEVLDWSGAPFAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTAAALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAIPDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQCCYTMRTIFDVKPDSDVFWCTADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTIYYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDVIGGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGYYFAGDGARIDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAEAAVVGVTDETTTQAICAFVVLRANYAPHDRTAEELRTEVARVISPIARPRDVHVVPELPKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIRAAK
>NC_021251.1|WP_003901692.1|4107796_4109422_-|ABC-transporter-substrate-binding-protein
MVRRMRAALAALATGLLVLAPVAGCGGGVLSPDVVLVNGGEPPNPLIPTGTNDSNGGRIIDRLFAGLMSYDAVGKPSLEVAQSIESADNVNYRITVKPGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAGAPGDKSRTTMSGLRVVNDLEFTVRLKAPTIDFTLRLGHSSFYPLPDSAFRDMAAFGRNPIGNGPYKLADGPAGPAWEHNVRIDLVPNPDYHGNRKPRNKGLRFEFYANLDTAYADLLSGNLDVLDTIPPSALTVYQRDLGDHATSGPAAINQTLDTPLRLPHFGGEEGRLRRLALSAAINRPQICQQIFAGTRSPARDFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAISPWSGRYAIAYNADAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQITNRAIDSAFRAGWRGDYPSMIEFLAPLFTAGAGSNDVGYINPEFDAALAAAEAAPTLTESHELVNDAQRILFHDMPVVPLWDYISVVGWSSQVSNVTVTWNGLPDYENIVKA
>NC_021251.1|WP_003419701.1|4106868_4107795_-|ABC-transporter-permease
MGWYVARRVAVMVPVFLGATLLIYGMVFLLPGDPVAALAGDRPLTPAVAAQLRSHYHLDDPFLVQYLRYLGGILHGDLGRAYSGLPVSAVLAHAFPVTIRLALIALAVEAVLGIGFGVIAGLRQGGIFDSAVLVTGLVIIAIPIFVLGFLAQFLFGVQLEIAPVTVGERASVGRLLLPGIVLGAMSFAYVVRLTRSAVAANAHADYVRTATAKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAIVTEGIFNIHGVGGVLYQAVTRQETPTVVSIVTVLVLIYLITNLLVDLLYAALDPRIRYG
>NC_021251.1|WP_003899628.1|4106012_4106876_-|ABC-transporter-permease
MAEHTGFWLDAWRGLRRRPKFVIAAALILLILVVAAFPSLFTAADPTYADPSQSMLAPSAAHWFGTDLQGHDIYSRTVYGARASVTVGLGATLAVFVVGGALGALAGFYGSWIDAVVSRVTDVFLGLPLLLAAIVLMQVMHHRTVWTVIAILALFGWPQVARIARGAVLEVRASDYVLAAKALGLNRFQILLRHALPNAVGPVIAVATVALGIFIVTEATLSYLGVGLPTSVVSWGGDINVAQTRLRSGSPILFYPAGALAITVLAFMMMGDALRDALDPASRAWRA
>NC_021251.1|WP_003900733.1|4104369_4106016_-|ABC-transporter-ATP-binding-protein
MSVPAAPLLSVEGLEVTFGTDAPAVCGVDLAVRSGQTVAVVGESGSGKSTTAAAILGLLPAGGRITAGRVVFDGRDITGADAKRLRSIRGREIGYVPQDPMTNLNPVWKVGFQVTEALRANTDGRAARRRAVELLAEAGLPDPAKQAGRYPHQLSGGMCQRALIAIGLAGRPRLLIADEPTSALDVTVQRQVLDHLQGLTDELGTALLLITHDLALAAQRAEAVVVVRRGVVVESGAAQSILQSPQHEYTRRLVAAAPSLTARSRRPPESRSRATTQAGDILVVSELTKIYRESRGAPWRRVESRAVDGVSFRLPRASTLAIVGESGSGKSTLARMVLGLLQPTSGTVVFDGTYDVGALARDQVLAFRRRVQPVFQNPYSSLDPMYSVFRAIEEPLRVHHVGDRRQRQRAVRELVDQVALPSSILGRRPRELSGGQRQRVAIARALALRPEVLVCDEAVSALDVLVQAQILDLLADLQADLGLTYLFISHDLAVIRQIADDVLVMRAGRVVEHASTEEVFSRPRHEYTRQLLQAIPGAPSAPRKVGNL
>NC_021251.1|WP_003899626.1|4103602_4104373_-|hypothetical-protein
MTVDPLAPLMELPGVAAASDRVRDALSRVHRHRANLRGWPVAAAEASLRAARASSVLDGGPARLHDAGAPTSGKPALSDPVFAGALRVGQALEGGAGPVVGVWRRAPLQALARLHMLAAADQVDDDRLGRPRSDADVGPRLELLADVVTHPTLASAPVVAAVAHGELLTLRPFGCADGVVARAVSRLVTIATGLDPHGLGVPEVIWMRQPAEYHDAARRFAGGTPDGVAGWLLLCCGAMLDGAREALSIAESLSPG
>NC_021251.1|WP_003419689.1|4101984_4102848_+|HAD-IB-family-hydrolase
MTVSDSPAQRQTPPQTPGGTAPRARTAAFFDLDKTIIAKSSTLAFSKPFFAQGLLNRRAVLKSSYAQFIFLLSGADHDQMDRMRTHLTNMCAGWDVAQVRSIVNETLHDIVTPLVFAEAADLIAAHKLCGRDVVVVSASGEEIVGPIARALGATHAMATRMIVEDGKYTGEVAFYCYGEGKAQAIRELAASEGYPLEHCYAYSDSITDLPMLEAVGHASVVNPDRGLRKEASVRGWPVLSFSRPVSLRDRIPAPSAAAIATTAAVGISALAAGAVTYALLRRFAFQP
>NC_021251.1|WP_003900732.1|4100433_4101486_-|septum-site-determining-protein-Ssd
MLTDPGLRDELDRVAAAVGVRVVHLGGRHPVSRKTWSAAAAVVLDHAAADRCGRLALPRRTHVSVLTGTEAATATWAAAITVGAQHVLRMPEQEGELVRELAEAAESARDDGICGAVVAVIGGRGGAGASLFAVALAQAAADALLVDLDPWAGGIDLLVGGETAPGLRWPDLALQGGRLNWSAVRAALPRPRGISVLSGTRRGYELDAGPVDAVIDAGRRGGVTVVCDLPRRLTDATQAALDAADLVVLVSPCDVRACAAAATMAPVLTAINPNLGLVVRGPSPGGLRAAEVADVAGVPLLASMRAQPRLAEQLEHGGLRLRRRSVLASAARRVLGVLPRAGSGRHGRAA
>NC_021251.1|WP_003899624.1|4099273_4100437_-|TadA-family-conjugal-transfer-associated-ATPase
MTGSLIERVRERLASESGPLRPSVVAAAIRAESGGMLGDTEVLANLRVLQTELTGAGILEPLLSADGTTDVLVTAPDSVWVDDGNGLRRSQIRFADESAVRRLAQRLALAAGRRLDDAQPWVDGQLTGIGVGGFAVRLHAVLPPVATQGTCLSLRVLRPATQDLAALAAAGAIDPAAAALVADIVTARLAFLVCGGTGAGKTTLLAAMLGAVSPDERIVCVEDAAELAPRHPHLVKLVARRANVEGIGEVTVRQLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHEGGAGTVHANNPGEVPARMEALGALGGLDRAALHSQLAAAVQVLLHVARDRAGRRRLAEIAVLRQAEGRVQAVTVWHADRGMSDDAAALHDLLRSRASA
>NC_021251.1|WP_003419710.1|4113164_4113683_+|phage-holin-family-protein
MSKIDRKNGVPSTLTTIPLADPHAGPAEPSIGDLIKDATTQMSTLVRAEVELARAEITRDVKKGLTGSVFFISSLVVGFYSTFFFFFFVAELLDTWIWRWVAFLLVFAIMVVVTAVLALLGFLKVRRIRGPRQTIASVKETRTALTPGHDKTPVTPKPVTSDRATPVDPSGW
>NC_021251.1|WP_003419712.1|4113683_4114667_+|alpha/beta-hydrolase
MAAPDPSMTRIAGPWRHLDVHANGIRFHVVEAVPSGQPEGPDAATPPMQPALARPLVILLHGFGSFWWSWRHQLCGLTGARVVAVDLRGYGGSDKPPRGYDGWTLAGDTAGLIRALGHPSATLVGHADGGLACWTTALLHSRLVRAIALISSPHPAALRRSTLTRRDQRHALLPTLLRYQLPIWPERLLTRNNAAEIERLVRARGCAKWLASEDFSQAIDHLRQAIQIPAAAHCALEYQRWAVRSQLRSEGRRFIRAMTQQLGMPLLHLRGDADPYVLADPVERTQRYAPHGRYISIAGAGHFSHEEAPEEVNRHLMRFLEQVHQLS
>NC_021251.1|WP_003419714.1|4114659_4115853_-|acid-resistance-serine-protease-MarP
MTPSQWLDIAVLAVAFIAAISGWRAGALGSMLSFGGVLLGATAGVLLAPHIVSQISAPRAKLFAALFLILALVVVGEVAGVVLGRAVRGAIRNRPIRLIDSVIGVGVQLVVVLTAAWLLAMPLTQSKEQPELAAAVKGSRVLARVNEAAPTWLKTVPKRLSALLNTSGLPAVLEPFSRTPVIPVASPDPALVNNPVVAATEPSVVKIRSLAPRCQKVLEGTGFVISPDRVMTNAHVVAGSNNVTVYAGDKPFEATVVSYDPSVDVAILAVPHLPPPPLVFAAEPAKTGADVVVLGYPGGGNFTATPARIREAIRLSGPDIYGDPEPVTRDVYTIRADVEQGDSGGPLIDLNGQVLGVVFGAAVDDAETGFVLTAGEVAGQLAKIGATQPVGTGACVS
>NC_021251.1|WP_003419718.1|4115858_4116680_-|CoA-pyrophosphatase
MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDAYRRRLPADVLAMVTAAGAVSAMTSSRRDHREAAVLVLFSGPEAGPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALREANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAETAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVISAVLDVAGWAQPWDTGDIRELDAAMVLIDDESDPR
>NC_021251.1|WP_003419721.1|4116811_4117495_-|TlpA-family-protein-disulfide-reductase
MPSLPTTPAETAMTTLTGKTRWTIAILAVVAALMAALVAQLHDYSASSTISQRPAPREHRDGDTPEALAWSRQRANLPPCPAAGNGPGAAALRGVVVVCAGDGSAVDVARALAGRRVVINLWAHWCAPCMTELPVMAEYQRRVGPAVLVVTVHQGQNEAAALSRLADLGVRLPTLQDDRRRVAAALRVANVMPATVVLRPDGSVAQTLPRAFGSADEIVAAVGNDAG
>NC_021251.1|WP_003902541.1|4117494_4118232_-|endonuclease-III
MRGRWSAETRLALVRRARRMNRALAQAFPHVYCELDFTTPLELAVATILSAQSTDKRVNLTTPALFARYRTARDYAQADRTELESLIRPTGFYRNKAASLIGLGQALVERFGGEVPATMDKLVTLPGVGRKTANVILGNAFGIPGITVDTHFGRLVRRWRWTTAEDPVKVEQAVGELIERKEWTLLSHRVIFHGRRVCHARRPACGVCVLAKDCPSFGLGPTEPLLAAPLVQGPETDHLLALAGL
>NC_021251.1|WP_003899635.1|4118339_4118717_+|hypothetical-protein
MFTLLVSWLLVACVPGLLMLATLGLGRLERFLARDTVTATDVAEFLEQAEAVDVHTLARNGMPEALDYLHRRQARRITDSPPLGSGAGPRYAGPLFVTDLDSPVEPPRHGQPNPQFRTARHANHV
>NC_021251.1|WP_003906177.1|4118815_4119490_+|cAMP-activated-global-transcriptional-regulator-CRP
MDEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGNRLYIIISGKVKIGRRAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIADRPEISEQLLRVLARRLRRTNNNLADLIFTDVPGRVAKQLLQLAQRFGTQEGGALRVTHDLTQEEIAQLVGASRETVNKALADFAHRGWIRLEGKSVLISDSERLARRAR
>NC_021251.1|WP_003419731.1|4119595_4120390_-|MBL-fold-metallo-hydrolase
MSKTAESLTHPAYGQLRAVTDTASVLLADNPGLLTLDGTNTWVLRGPLSDELVVVDPGPDDDEHLARVAALGRIALVLISHRHGDHTSGIDKLVALTGAPVRAADPQFLRRDGETLTDGEVIDVAGLTITVLATPGHTADSLSFVLDDAVLTADTVLGCGTTVIDKEDGSLADYLESLHRLRGLGRRTVLPGHGPDLLDLEAIASGYLLHRHERLEQIRAALRDLGDDATVREVVEHVYLDVDEKLWNAAEWSVQAQLDYLRTR
>NC_021251.1|WP_003419733.1|4120396_4120852_-|RidA-family-protein
MSAKARLGQLGVTLPQVAAPLAAYVPAVRTGNLVYTAGQLPLEAGKLVRTGKLGADVNPEEGKTLARICALNALAAVDSLVDLDAVTRVVKVVGFVASAPGFHGQPSVINGASDLLAEVFGDSGAHARSAVGVSELPLDAPVEVELIVEVG

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_021251_9	9.1|3656514|59|NC_021251|CRISPRCasFinder	3656514-3656572	59	NC_021251.1	3656577-3656635	0	1.0
NC_021251_2	2.1|629695|18|NC_021251|CRT	629695-629712	18	NC_021251.1	23824-23841	1	0.944
NC_021251_2	2.1|629695|18|NC_021251|CRT	629695-629712	18	NC_021251.1	1412054-1412071	1	0.944
NC_021251_2	2.3|629779|18|NC_021251|CRT	629779-629796	18	NC_021251.1	971805-971822	1	0.944
NC_021251_6	6.2|2073653|18|NC_021251|CRT	2073653-2073670	18	NC_021251.1	399457-399474	1	0.944
NC_021251_6	6.2|2073653|18|NC_021251|CRT	2073653-2073670	18	NC_021251.1	605732-605749	1	0.944
NC_021251_6	6.4|2073743|18|NC_021251|CRT	2073743-2073760	18	NC_021251.1	3440448-3440465	1	0.944
NC_021251_1	1.5|365162|42|NC_021251|CRISPRCasFinder	365162-365203	42	NC_021251.1	373178-373219	2	0.952
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NC_021251.1	371993-372025	2	0.939
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NC_021251.1	1210775-1210796	2	0.909

1. spacer 9.1|3656514|59|NC_021251|CRISPRCasFinder matches to position: 3656577-3656635, mismatch: 0, identity: 1.0

ctgtgagtcgagtgagcggaacgaacgaagtgagtgacgggaacgagacgaacaatccg	CRISPR spacer
ctgtgagtcgagtgagcggaacgaacgaagtgagtgacgggaacgagacgaacaatccg	Protospacer
***********************************************************

2. spacer 2.1|629695|18|NC_021251|CRT matches to position: 23824-23841, mismatch: 1, identity: 0.944

accacgtcggcgacgacg	CRISPR spacer
acgacgtcggcgacgacg	Protospacer
** ***************

3. spacer 2.1|629695|18|NC_021251|CRT matches to position: 1412054-1412071, mismatch: 1, identity: 0.944

accacgtcggcgacgacg	CRISPR spacer
acctcgtcggcgacgacg	Protospacer
*** **************

4. spacer 2.3|629779|18|NC_021251|CRT matches to position: 971805-971822, mismatch: 1, identity: 0.944

accacgccgccaacgacg	CRISPR spacer
accacgccgcccacgacg	Protospacer
*********** ******

5. spacer 6.2|2073653|18|NC_021251|CRT matches to position: 399457-399474, mismatch: 1, identity: 0.944

gatcagcccgacggcgtt	CRISPR spacer
gatcagcccgtcggcgtt	Protospacer
********** *******

6. spacer 6.2|2073653|18|NC_021251|CRT matches to position: 605732-605749, mismatch: 1, identity: 0.944

gatcagcccgacggcgtt	CRISPR spacer
gatcagcccgtcggcgtt	Protospacer
********** *******

7. spacer 6.4|2073743|18|NC_021251|CRT matches to position: 3440448-3440465, mismatch: 1, identity: 0.944

gatcagcgtcccgccggt	CRISPR spacer
gatcagcgtcccgctggt	Protospacer
**************.***

8. spacer 1.5|365162|42|NC_021251|CRISPRCasFinder matches to position: 373178-373219, mismatch: 2, identity: 0.952

ccggtgcccgagttgaagaacccgatgtttccgctgccggag	CRISPR spacer
ccggtgcccgagttgaacaacccgacgtttccgctgccggag	Protospacer
***************** *******.****************

9. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to position: 371993-372025, mismatch: 2, identity: 0.939

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
aggctgccgaacccgatctggccgctgccggtg	Protospacer
********** *************.********

10. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to position: 1210775-1210796, mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gttgccgatcagcccggcggca	Protospacer
**.********* *********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	1975819-1975840	1	0.955
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1109892-1109913	1	0.955
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP016457	Sphingobium sp. RAC03 plasmid pBSY17_2, complete sequence	87869-87890	1	0.955
NC_021251_4	4.15|1574776|22|NC_021251|CRISPRCasFinder	1574776-1574797	22	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	362668-362689	1	0.955
NC_021251_4	4.15|1574776|22|NC_021251|CRISPRCasFinder	1574776-1574797	22	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2289382-2289403	1	0.955
NC_021251_4	4.15|1574776|22|NC_021251|CRISPRCasFinder	1574776-1574797	22	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	81656-81677	1	0.955
NC_021251_4	4.15|1574776|22|NC_021251|CRISPRCasFinder	1574776-1574797	22	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	56160-56181	1	0.955
NC_021251_4	4.2|1573849|22|NC_021251|CRISPRCasFinder	1573849-1573870	22	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	881140-881161	2	0.909
NC_021251_4	4.2|1573849|22|NC_021251|CRISPRCasFinder	1573849-1573870	22	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	225972-225993	2	0.909
NC_021251_4	4.2|1573849|22|NC_021251|CRISPRCasFinder	1573849-1573870	22	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	451168-451189	2	0.909
NC_021251_4	4.2|1573849|22|NC_021251|CRISPRCasFinder	1573849-1573870	22	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	234992-235013	2	0.909
NC_021251_4	4.2|1573849|22|NC_021251|CRISPRCasFinder	1573849-1573870	22	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	597449-597470	2	0.909
NC_021251_4	4.3|1573903|22|NC_021251|CRISPRCasFinder	1573903-1573924	22	NZ_CP025510	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence	117076-117097	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP021032	Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence	448838-448859	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NC_007765	Rhizobium etli CFN 42 plasmid p42e, complete sequence	160471-160492	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP021028	Rhizobium sp. TAL182 plasmid pRetTAL182d, complete sequence	175264-175285	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP013634	Rhizobium sp. N324 plasmid pRspN324d, complete sequence	457593-457614	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP013503	Rhizobium esperanzae strain N561 plasmid pRspN561c, complete sequence	166709-166730	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP013509	Rhizobium sp. N1341 plasmid pRspN1341d, complete sequence	166709-166730	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP013520	Rhizobium sp. N113 plasmid pRspN113c, complete sequence	166709-166730	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP013493	Rhizobium sp. N6212 plasmid pRspN6212c, complete sequence	166709-166730	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP013516	Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence	164465-164486	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	97458-97479	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP012698	Microbacterium sp. No. 7 plasmid A, complete sequence	53118-53139	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	100830-100851	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	307854-307875	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	23841-23862	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	279961-279982	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	359201-359222	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	606826-606847	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	411558-411579	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP054029	Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence	300111-300132	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	483830-483851	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP024312	Rhizobium sp. NXC24 plasmid pRspNXC24a, complete sequence	68146-68167	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	CP042595	Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence	175112-175133	2	0.909
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	314082-314103	2	0.909
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	402883-402907	2	0.92
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	416172-416196	2	0.92
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	472935-472959	2	0.92
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_KY349138	Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_2, complete sequence	9264-9285	3	0.864
NC_021251_4	4.4|1573957|22|NC_021251|CRISPRCasFinder	1573957-1573978	22	NZ_CP021649	Acidovorax sp. T1 plasmid p1-T1, complete sequence	13233-13254	3	0.864
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	937294-937318	3	0.88
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_CP022999	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence	1470762-1470786	3	0.88
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	MN586053	Arthrobacter phage BeatusComedenti, complete genome	26689-26713	3	0.88
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NC_031254	Arthrobacter phage Kitkat, complete genome	26809-26833	3	0.88
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NC_031231	Arthrobacter phage KellEzio, complete genome	26691-26715	3	0.88
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	633177-633201	3	0.88
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_CP030129	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed3, complete sequence	74124-74148	3	0.88
NC_021251_4	4.15|1574776|22|NC_021251|CRISPRCasFinder	1574776-1574797	22	NC_008270	Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence	380879-380900	3	0.864
NC_021251_6	6.5|2073782|24|NC_021251|CRT	2073782-2073805	24	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	1555522-1555545	3	0.875
NC_021251_6	6.5|2073782|24|NC_021251|CRT	2073782-2073805	24	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	1560190-1560213	3	0.875
NC_021251_1	1.1|364907|27|NC_021251|CRISPRCasFinder	364907-364933	27	NC_023591	Mycobacterium phage Adler, complete genome	61249-61275	4	0.852
NC_021251_1	1.1|364907|27|NC_021251|CRISPRCasFinder	364907-364933	27	KF981876	UNVERIFIED: Mycobacterium phage ADLER F1725, complete genome	61247-61273	4	0.852
NC_021251_1	1.7|365303|27|NC_021251|CRISPRCasFinder	365303-365329	27	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	10066-10092	4	0.852
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	460464-460490	4	0.852
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NC_016652	Rhodococcus phage REQ2, complete genome	36035-36061	4	0.852
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	603744-603773	4	0.867
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	818773-818800	4	0.857
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	420542-420569	4	0.857
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	77799-77826	4	0.857
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_CP021372	Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence	176640-176664	4	0.84
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	LR134127	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 7	29428-29452	4	0.84
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	LR134127	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 7	38191-38215	4	0.84
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	MT553342	Microbacterium phage Kelcole, complete genome	51573-51597	4	0.84
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NC_048068	Microbacterium phage OneinaGillian, complete genome	50894-50918	4	0.84
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	MT310894	Microbacterium phage Tempo, complete genome	51697-51721	4	0.84
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_CP047175	Rathayibacter sp. VKM Ac-2760 plasmid unnamed2, complete sequence	42080-42104	4	0.84
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_CP013631	Rhizobium sp. N324 plasmid pRspN324a, complete sequence	67777-67801	4	0.84
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	MN034284	Leviviridae sp. isolate H2_Rhizo_Litter_49_scaffold_25938 sequence	624-648	4	0.84
NC_021251_4	4.14|1574719|25|NC_021251|CRISPRCasFinder	1574719-1574743	25	MN582064	Podoviridae sp. ctka020, complete genome	29274-29298	4	0.84
NC_021251_6	6.5|2073782|24|NC_021251|CRT	2073782-2073805	24	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	680430-680453	4	0.833
NC_021251_6	6.5|2073782|24|NC_021251|CRT	2073782-2073805	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5913119-5913142	4	0.833
NC_021251_6	6.5|2073782|24|NC_021251|CRT	2073782-2073805	24	NZ_CP015007	Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence	143186-143209	4	0.833
NC_021251_1	1.1|364907|27|NC_021251|CRISPRCasFinder	364907-364933	27	LR794124	Vibrio phage vB_Vc_SrVc9 genome assembly, chromosome: 1	34861-34887	5	0.815
NC_021251_1	1.1|364907|27|NC_021251|CRISPRCasFinder	364907-364933	27	NC_012662	Vibrio phage VP93, complete genome	35301-35327	5	0.815
NC_021251_1	1.7|365303|27|NC_021251|CRISPRCasFinder	365303-365329	27	NZ_CP016084	Streptomyces sp. SAT1 plasmid unnamed4, complete sequence	2189-2215	5	0.815
NC_021251_1	1.7|365303|27|NC_021251|CRISPRCasFinder	365303-365329	27	MN693945	Marine virus AFVG_250M952, complete genome	34909-34935	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	369429-369455	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013525	Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence	338832-338858	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013554	Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence	363377-363403	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP015368	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence	104717-104743	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013588	Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence	338543-338569	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013560	Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence	340811-340837	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013577	Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence	342690-342716	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013549	Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence	343060-343086	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013529	Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence	355714-355740	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013534	Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence	343060-343086	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	348335-348361	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013545	Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence	343052-343078	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP020444	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed4, complete sequence	69464-69490	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013565	Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence	363377-363403	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013582	Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence	355714-355740	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP013571	Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence	342690-342716	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP044078	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed1, complete sequence	10340-10366	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP031081	Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence	19365-19391	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	MN586031	Gordonia phage Gambino, complete genome	3053-3079	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	KU998236	Gordonia phage Blueberry, complete genome	3053-3079	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	MN062704	Gordonia phage JuJu, complete genome	3063-3089	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	MK501729	Gordonia phage Walrus, complete genome	3053-3079	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NC_031226	Gordonia phage BaxterFox, complete genome	2982-3008	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	MK967393	Rhodococcus phage Whack, complete genome	3063-3089	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	MT723935	Gordonia phage Azula, complete genome	3053-3079	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	KU963249	Gordonia phage Yeezy, complete genome	2982-3008	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	MH153808	Gordonia phage Petra, complete genome	3053-3079	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	MT639650	Gordonia phage Ohgeesy, complete genome	2982-3008	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	MH536818	Gordonia phage Frokostdame, complete genome	3055-3081	5	0.815
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	KX557275	Gordonia phage CarolAnn, complete genome	3052-3078	5	0.815
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	NZ_LN907828	Erwinia gerundensis isolate E_g_EM595 plasmid pEM01, complete sequence	94483-94510	5	0.821
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	KU728633	Mycobacterium phage Bipper, complete genome	41992-42019	5	0.821
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	MK977701	Mycobacterium phage Cracklewink, complete genome	41985-42012	5	0.821
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	NZ_CP016354	Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence	100320-100347	5	0.821
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_CP025013	Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence	614111-614135	5	0.8
NC_021251_4	4.5|1574011|25|NC_021251|CRISPRCasFinder	1574011-1574035	25	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	92705-92729	5	0.8
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NC_018746	Pseudomonas putida ND6 plasmid pND6-2, complete sequence	45440-45470	5	0.839
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	MN961671	Pseudomonas aeruginosa strain 201330 plasmid p201330-IMP, complete sequence	123562-123592	5	0.839
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	MN961672	Pseudomonas aeruginosa strain PA15W plasmid pPA15W-NR, complete sequence	72551-72581	5	0.839
NC_021251_4	4.13|1574653|34|NC_021251|CRISPRCasFinder	1574653-1574686	34	NC_006362	Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence	89410-89443	5	0.853
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NC_010850	Rhodococcus sp. NS1 plasmid pNSL1, complete sequence	92901-92931	5	0.839
NC_021251_1	1.1|364907|27|NC_021251|CRISPRCasFinder	364907-364933	27	NZ_CP045917	Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence	207335-207361	6	0.778
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	435770-435802	6	0.818
NC_021251_1	1.7|365303|27|NC_021251|CRISPRCasFinder	365303-365329	27	NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	32942-32968	6	0.778
NC_021251_1	1.9|365453|27|NC_021251|CRISPRCasFinder	365453-365479	27	NC_009959	Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI05, complete sequence	50750-50776	6	0.778
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	179708-179734	6	0.778
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4846911-4846937	6	0.778
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	78863-78889	6	0.778
NC_021251_1	1.10|365513|27|NC_021251|CRISPRCasFinder	365513-365539	27	MK494099	Mycobacterium phage Typha, complete genome	33831-33857	6	0.778
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1565268-1565297	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	KX620751	Propionibacterium phage Doucette, complete genome	8876-8905	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NC_041891	Propionibacterium phage B22, complete genome	8817-8846	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NC_041894	Propionibacterium phage E6, complete genome	8927-8956	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	KX620754	Propionibacterium phage G4, complete genome	8865-8894	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP030127	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence	575683-575712	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1829167-1829196	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	MT818419	Mycobacterium phage Lolalove, complete genome	27446-27475	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	MN428050	Mycobacterium phage Apex, complete genome	27615-27644	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	MN234171	Mycobacterium phage Magpie, complete genome	27275-27304	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	KX589269	Mycobacterium phage Fortunato, complete genome	27431-27460	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NC_042035	Mycobacterium phage Zemanar, complete sequence	27435-27464	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NC_022331	Mycobacterium phage Bane1, complete genome	27108-27137	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	KF279413	Mycobacterium phage Bane2, complete genome	27087-27116	6	0.8
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	MT310870	Mycobacterium phage RawrgerThat, complete genome	27434-27463	6	0.8
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	GQ141189	Bifidobacterium phage Bbif-1, complete sequence	38062-38092	6	0.806
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	NZ_AP022571	Mycolicibacterium poriferae strain JCM 12603 plasmid pJCM12603, complete sequence	39276-39303	6	0.786
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	NC_008703	Mycobacterium sp. KMS plasmid pMKMS01, complete sequence	76834-76861	6	0.786
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	NZ_LR594663	Variovorax sp. RA8 plasmid 2	131793-131820	6	0.786
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_LR594669	Variovorax sp. SRS16 plasmid 4	27764-27794	6	0.806
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	438646-438676	6	0.806
NC_021251_4	4.13|1574653|34|NC_021251|CRISPRCasFinder	1574653-1574686	34	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	28989-29022	6	0.824
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NC_009478	Clavibacter michiganensis subsp. michiganensis NCPPB 382 plasmid pCM1, complete sequence	8328-8358	6	0.806
NC_021251_12	12.12|3934661|30|NC_021251|CRT	3934661-3934690	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5232057-5232086	6	0.8
NC_021251_1	1.4|365102|27|NC_021251|CRISPRCasFinder	365102-365128	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	48081-48107	7	0.741
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2600082-2600111	7	0.767
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2593965-2593994	7	0.767
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	LR134127	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 7	110413-110442	7	0.767
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NC_005241	Cupriavidus necator H16 megaplasmid pHG1, complete sequence	444400-444429	7	0.767
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	741115-741144	7	0.767
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP012478	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed1, complete sequence	144936-144965	7	0.767
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP039289	Cupriavidus necator H16 plasmid pHG1, complete sequence	444383-444412	7	0.767
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP014600	Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence	66483-66512	7	0.767
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	320484-320513	7	0.767
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NC_042034	Mycobacterium phage ChrisnMich, complete sequence	26400-26429	7	0.767
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MK977708	Mycobacterium phage Fulbright, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MG099948	Mycobacterium phage Philonius, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MH926055	Mycobacterium phage Chewbacca, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MT723932	Mycobacterium phage Schnauzer, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	KU935726	Mycobacterium phage Xerxes, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	KU935730	Mycobacterium phage Pipsqueaks, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MH316570	Mycobacterium phage Silvafighter, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MK524518	Mycobacterium phage Smurph, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MK524515	Mycobacterium phage Parmesanjohn, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MH697585	Mycobacterium phage Gex, complete genome	10280-10310	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	KM588359	Mycobacterium phage Carcharodon, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MH697576	Mycobacterium phage Aggie, complete genome	10282-10312	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MH697593	Mycobacterium phage Tapioca, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	MG099936	Mycobacterium phage Andies, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	NC_031243	Mycobacterium phage Xeno, complete genome	10281-10311	7	0.774
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	JN256079	Mycobacterium phage Charlie, complete genome	10281-10311	7	0.774
NC_021251_4	4.1|1573789|28|NC_021251|CRISPRCasFinder	1573789-1573816	28	NC_010553	Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence	259627-259654	7	0.75
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP041045	Paracoccus sp. AK26 plasmid pAK1, complete sequence	281800-281830	7	0.774
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	CP017041	Propionibacterium sp. oral taxon 193 strain F0672 plasmid unnamed1, complete sequence	68407-68437	7	0.774
NC_021251_6	6.3|2073692|30|NC_021251|CRT	2073692-2073721	30	NZ_CP015065	Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence	52187-52216	7	0.767
NC_021251_6	6.3|2073692|30|NC_021251|CRT	2073692-2073721	30	NZ_CP015063	Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence	75140-75169	7	0.767
NC_021251_6	6.3|2073692|30|NC_021251|CRT	2073692-2073721	30	NC_014918	Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence	376489-376518	7	0.767
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	147567-147597	7	0.774
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP012186	Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence	36995-37025	7	0.774
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP042263	Litoreibacter sp. LN3S51 plasmid unnamed2, complete sequence	372247-372277	7	0.774
NC_021251_12	12.12|3934661|30|NC_021251|CRT	3934661-3934690	30	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	1166919-1166948	7	0.767
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	1386736-1386768	8	0.758
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	35126-35158	8	0.758
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1241611-1241643	8	0.758
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	CP007644	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence	275839-275871	8	0.758
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	310597-310629	8	0.758
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP045074	Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence	437642-437671	8	0.733
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP015269	Mycobacterium chimaera strain ZUERICH-2 plasmid unnamed 2, complete sequence	9052-9081	8	0.733
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	349053-349083	8	0.742
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP039899	Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence	336247-336277	8	0.742
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP039913	Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625b, complete sequence	262996-263026	8	0.742
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP039890	Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence	336247-336277	8	0.742
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP018001	Rhizobium sp. Y9 plasmid pY9, complete sequence	264529-264559	8	0.742
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NC_022536	Rhizobium sp. IRBG74 plasmid IRBL74_p, complete sequence	458177-458207	8	0.742
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP053858	Rhizobium pusense strain 76 plasmid pR76, complete sequence	311056-311086	8	0.742
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	88587-88617	8	0.742
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	CP036360	Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence	284157-284187	8	0.742
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP021914	Sagittula sp. P11 plasmid unnamed1, complete sequence	300067-300097	8	0.742
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1510497-1510527	8	0.742
NC_021251_6	6.3|2073692|30|NC_021251|CRT	2073692-2073721	30	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	9194-9223	8	0.733
NC_021251_6	6.3|2073692|30|NC_021251|CRT	2073692-2073721	30	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	983284-983313	8	0.733
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	CP033373	Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence	12237-12267	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1260343-1260373	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1009358-1009388	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1260501-1260531	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1009351-1009381	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	756669-756699	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1137767-1137797	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1009365-1009395	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1260057-1260087	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1260001-1260031	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	981946-981976	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	938267-938297	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	748414-748444	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	896022-896052	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NZ_CP027299	Streptomyces sp. SGAir0924 plasmid unnamed_5	215713-215743	8	0.742
NC_021251_10	10.7|3739443|31|NC_021251|CRT	3739443-3739473	31	NC_014213	Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence	111748-111778	8	0.742
NC_021251_12	12.9|3934430|39|NC_021251|CRT	3934430-3934468	39	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	770469-770507	8	0.795
NC_021251_12	12.12|3934661|30|NC_021251|CRT	3934661-3934690	30	NZ_CP048385	Citrobacter freundii strain 62 plasmid p6_C, complete sequence	53917-53946	8	0.733
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	91175-91207	9	0.727
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	668963-668995	9	0.727
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	789706-789738	9	0.727
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP048281	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence	625853-625885	9	0.727
NC_021251_2	2.2|629731|30|NC_021251|CRT	629731-629760	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1695112-1695141	9	0.7
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	NZ_CP014964	Geobacter anodireducens strain SD-1 plasmid pSD, complete sequence	13698-13728	9	0.71
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	NC_015974	Sphingobium sp. SYK-6 plasmid pSLPG, complete sequence	20960-20990	9	0.71
NC_021251_3	3.1|690438|31|NC_021251|CRISPRCasFinder	690438-690468	31	NZ_CP005085	Sphingobium sp. TKS plasmid pTK1, complete sequence	15390-15420	9	0.71
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	345043-345073	9	0.71
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	245050-245080	9	0.71
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NC_022049	Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence	194387-194417	9	0.71
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	MN234199	Mycobacterium phage Ekdilam, complete genome	24235-24265	9	0.71
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP023000	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence	1145162-1145192	9	0.71
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP015737	Shinella sp. HZN7 plasmid pShin-01, complete sequence	453136-453166	9	0.71
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP013740	Streptomyces globisporus C-1027 plasmid pSGL1, complete sequence	2806-2836	9	0.71
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1908459-1908489	9	0.71
NC_021251_10	10.5|3739302|34|NC_021251|CRT	3739302-3739335	34	NZ_CP021805	Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence	922290-922323	9	0.735
NC_021251_10	10.5|3739302|34|NC_021251|CRT	3739302-3739335	34	MG812496	Gordonia phage SallySpecial, complete genome	7675-7708	9	0.735
NC_021251_10	10.9|3739575|37|NC_021251|CRT	3739575-3739611	37	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	975062-975098	9	0.757
NC_021251_12	12.9|3934430|39|NC_021251|CRT	3934430-3934468	39	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	414874-414912	9	0.769
NC_021251_12	12.9|3934430|39|NC_021251|CRT	3934430-3934468	39	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1604227-1604265	9	0.769
NC_021251_12	12.9|3934430|39|NC_021251|CRT	3934430-3934468	39	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	68975-69013	9	0.769
NC_021251_12	12.12|3934661|30|NC_021251|CRT	3934661-3934690	30	NC_012725	Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence	105939-105968	9	0.7
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	91179-91211	10	0.697
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	90245-90277	10	0.697
NC_021251_1	1.6|365237|33|NC_021251|CRISPRCasFinder	365237-365269	33	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	99166-99198	10	0.697
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	425898-425928	10	0.677
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	344090-344120	10	0.677
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	68383-68413	10	0.677
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NC_017590	Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence	16322-16352	10	0.677
NC_021251_4	4.10|1574404|31|NC_021251|CRISPRCasFinder	1574404-1574434	31	NZ_AP014581	Burkholderia sp. RPE67 plasmid p3, complete sequence	131907-131937	10	0.677
NC_021251_4	4.13|1574653|34|NC_021251|CRISPRCasFinder	1574653-1574686	34	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	1081518-1081551	10	0.706
NC_021251_8	8.9|3114598|35|NC_021251|PILER-CR,CRISPRCasFinder,CRT	3114598-3114632	35	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	414652-414686	10	0.714
NC_021251_10	10.5|3739302|34|NC_021251|CRT	3739302-3739335	34	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	470079-470112	10	0.706
NC_021251_10	10.5|3739302|34|NC_021251|CRT	3739302-3739335	34	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	68774-68807	10	0.706
NC_021251_10	10.5|3739302|34|NC_021251|CRT	3739302-3739335	34	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	172270-172303	10	0.706
NC_021251_10	10.5|3739302|34|NC_021251|CRT	3739302-3739335	34	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	172270-172303	10	0.706
NC_021251_10	10.5|3739302|34|NC_021251|CRT	3739302-3739335	34	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	326578-326611	11	0.676
NC_021251_10	10.9|3739575|37|NC_021251|CRT	3739575-3739611	37	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	232224-232260	11	0.703

1. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 1, identity: 0.955

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccggcggcc	Protospacer
********************* 

2. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.955

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccggcggcc	Protospacer
********************* 

3. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP016457 (Sphingobium sp. RAC03 plasmid pBSY17_2, complete sequence) position: , mismatch: 1, identity: 0.955

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcgggccggcggca	Protospacer
**********.***********

4. spacer 4.15|1574776|22|NC_021251|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.955

caatccggcggcgccgccggca	CRISPR spacer
caattcggcggcgccgccggca	Protospacer
****.*****************

5. spacer 4.15|1574776|22|NC_021251|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.955

caatccggcggcgccgccggca	CRISPR spacer
caattcggcggcgccgccggca	Protospacer
****.*****************

6. spacer 4.15|1574776|22|NC_021251|CRISPRCasFinder matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 1, identity: 0.955

caatccggcggcgccgccggca	CRISPR spacer
caattcggcggcgccgccggca	Protospacer
****.*****************

7. spacer 4.15|1574776|22|NC_021251|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 1, identity: 0.955

caatccggcggcgccgccggca	CRISPR spacer
caattcggcggcgccgccggca	Protospacer
****.*****************

8. spacer 4.2|1573849|22|NC_021251|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 2, identity: 0.909

gttgccgattaggacggcggcc	CRISPR spacer
cttgccgatcaggacggcggcc	Protospacer
 ********.************

9. spacer 4.2|1573849|22|NC_021251|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 2, identity: 0.909

gttgccgattaggacggcggcc	CRISPR spacer
cttgccgatcaggacggcggcc	Protospacer
 ********.************

10. spacer 4.2|1573849|22|NC_021251|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 2, identity: 0.909

gttgccgattaggacggcggcc	CRISPR spacer
cttgccgatcaggacggcggcc	Protospacer
 ********.************

11. spacer 4.2|1573849|22|NC_021251|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 2, identity: 0.909

gttgccgattaggacggcggcc	CRISPR spacer
cttgccgatcaggacggcggcc	Protospacer
 ********.************

12. spacer 4.2|1573849|22|NC_021251|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 2, identity: 0.909

gttgccgattaggacggcggcc	CRISPR spacer
cttgccgatcaggacggcggcc	Protospacer
 ********.************

13. spacer 4.3|1573903|22|NC_021251|CRISPRCasFinder matches to NZ_CP025510 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence) position: , mismatch: 2, identity: 0.909

ggtaccgtcctcgccggcggtg	CRISPR spacer
ggcaccgtcctcgccggcggtt	Protospacer
**.****************** 

14. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP021032 (Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcc	Protospacer
.******************** 

15. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NC_007765 (Rhizobium etli CFN 42 plasmid p42e, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

16. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP021028 (Rhizobium sp. TAL182 plasmid pRetTAL182d, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

17. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP013634 (Rhizobium sp. N324 plasmid pRspN324d, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcc	Protospacer
.******************** 

18. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP013503 (Rhizobium esperanzae strain N561 plasmid pRspN561c, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

19. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP013509 (Rhizobium sp. N1341 plasmid pRspN1341d, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

20. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP013520 (Rhizobium sp. N113 plasmid pRspN113c, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

21. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP013493 (Rhizobium sp. N6212 plasmid pRspN6212c, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

22. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP013516 (Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

23. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccggcgggg	Protospacer
******************** .

24. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP012698 (Microbacterium sp. No. 7 plasmid A, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
accgccgatcaggccggcggca	Protospacer
..********************

25. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
ctcggcgatcaggccggcggca	Protospacer
 *** *****************

26. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatccggccggcggct	Protospacer
********** ********** 

27. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccgggggcc	Protospacer
***************** *** 

28. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccgggggcc	Protospacer
***************** *** 

29. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatccggccggcggct	Protospacer
********** ********** 

30. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccgggggcg	Protospacer
***************** ***.

31. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
ggcgccgatcaggccggcggcc	Protospacer
* ******************* 

32. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP054029 (Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggcctgcggcg	Protospacer
*************** *****.

33. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatccggccggcggct	Protospacer
********** ********** 

34. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP024312 (Rhizobium sp. NXC24 plasmid pRspNXC24a, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccggcgccg	Protospacer
******************* *.

35. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to CP042595 (Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgagcaggccggcggcc	Protospacer
******** ************ 

36. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccgggggcc	Protospacer
***************** *** 

37. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.92

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cttgccgaacccgccgaacccgtcg	Protospacer
********** ******* ******

38. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.92

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cttgccgaacccgccgaacccgtcg	Protospacer
********** ******* ******

39. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.92

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cttgccgaacccgccgaacccgtcg	Protospacer
********** ******* ******

40. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_KY349138 (Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_2, complete sequence) position: , mismatch: 3, identity: 0.864

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccggcgcgg	Protospacer
*******************  .

41. spacer 4.4|1573957|22|NC_021251|CRISPRCasFinder matches to NZ_CP021649 (Acidovorax sp. T1 plasmid p1-T1, complete sequence) position: , mismatch: 3, identity: 0.864

gtcgccgatcaggccggcggca	CRISPR spacer
ttcgccgatcaggccggcggtg	Protospacer
 *******************..

42. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
ctcgccgaacacgcggaagccgtct	Protospacer
**.*********** ********* 

43. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_CP022999 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
attgtcgaacacgcggaagccgtcg	Protospacer
 ***.********* **********

44. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to MN586053 (Arthrobacter phage BeatusComedenti, complete genome) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gttgccgaactcgccgaagccgttg	Protospacer
 ********* ************.*

45. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NC_031254 (Arthrobacter phage Kitkat, complete genome) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gttgccgaactcgccgaagccgttg	Protospacer
 ********* ************.*

46. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NC_031231 (Arthrobacter phage KellEzio, complete genome) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gttgccgaactcgccgaagccgttg	Protospacer
 ********* ************.*

47. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
catgcggaacacgccgaatccgtcg	Protospacer
* *** ************ ******

48. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_CP030129 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cttgccgatcacgccgtagccgttg	Protospacer
******** ******* ******.*

49. spacer 4.15|1574776|22|NC_021251|CRISPRCasFinder matches to NC_008270 (Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence) position: , mismatch: 3, identity: 0.864

caatccggcggcgccgccggca	CRISPR spacer
gaatccggcggcgccgccgggc	Protospacer
 *******************  

50. spacer 6.5|2073782|24|NC_021251|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 3, identity: 0.875

atcgaagaagctgaacccgccgtt	CRISPR spacer
cgcgaagaagctgaagccgccgtt	Protospacer
  ************* ********

51. spacer 6.5|2073782|24|NC_021251|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 3, identity: 0.875

atcgaagaagctgaacccgccgtt	CRISPR spacer
cgcgaagaagctgaagccgccgtt	Protospacer
  ************* ********

52. spacer 1.1|364907|27|NC_021251|CRISPRCasFinder matches to NC_023591 (Mycobacterium phage Adler, complete genome) position: , mismatch: 4, identity: 0.852

-aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
cagtgc-ccggtgtccccatcgcccgtg	Protospacer
 *..** ********* ***********

53. spacer 1.1|364907|27|NC_021251|CRISPRCasFinder matches to KF981876 (UNVERIFIED: Mycobacterium phage ADLER F1725, complete genome) position: , mismatch: 4, identity: 0.852

-aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
cagtgc-ccggtgtccccatcgcccgtg	Protospacer
 *..** ********* ***********

54. spacer 1.7|365303|27|NC_021251|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 4, identity: 0.852

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
ccgaagccgatgtcgtagcggccggcg	Protospacer
 ************.***** *****.*

55. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.852

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgaaggtgaggtcgccgggg	Protospacer
.* ********* ***********.**

56. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NC_016652 (Rhodococcus phage REQ2, complete genome) position: , mismatch: 4, identity: 0.852

accccgccgaagttgaggtcgccgagg	CRISPR spacer
acggcgccgaagttgaggccgccgacg	Protospacer
**  **************.****** *

57. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 4, identity: 0.867

accacgccggtgaccacgccg-ccaacgacg	CRISPR spacer
accacgccggtggccacgccgaccagcggc-	Protospacer
************.******** ***.**.* 

58. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 4, identity: 0.857

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gccgccgggggtgccctcgttgccgggc	Protospacer
*..************ ********** *

59. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 4, identity: 0.857

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gccgccgggggtgccctcgttgccgggc	Protospacer
*..************ ********** *

60. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 4, identity: 0.857

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gccgccgggggtgccctcgttgccgggc	Protospacer
*..************ ********** *

61. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_CP021372 (Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
tccgccgaacgcgccgaagccgtcg	Protospacer
...*******.**************

62. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to LR134127 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 7) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gctgccgaacacgccgatgccgacg	Protospacer
 .*************** **** **

63. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to LR134127 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 7) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gctgccgaacacgccgatgccgacg	Protospacer
 .*************** **** **

64. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to MT553342 (Microbacterium phage Kelcole, complete genome) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gatgctgatcacgccgaagccgtcg	Protospacer
  ***.** ****************

65. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NC_048068 (Microbacterium phage OneinaGillian, complete genome) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gatgctgatcacgccgaagccgtcg	Protospacer
  ***.** ****************

66. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to MT310894 (Microbacterium phage Tempo, complete genome) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gatgctgatcacgccgaagccgtcg	Protospacer
  ***.** ****************

67. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_CP047175 (Rathayibacter sp. VKM Ac-2760 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cttgccgaacacgccgatgccctgc	Protospacer
***************** *** *  

68. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_CP013631 (Rhizobium sp. N324 plasmid pRspN324a, complete sequence) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
aatgccgaattcgccgaagccgtcg	Protospacer
  *******. **************

69. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to MN034284 (Leviviridae sp. isolate H2_Rhizo_Litter_49_scaffold_25938 sequence) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cccgtagaacacgccgaagccgtcg	Protospacer
*..*. *******************

70. spacer 4.14|1574719|25|NC_021251|CRISPRCasFinder matches to MN582064 (Podoviridae sp. ctka020, complete genome) position: , mismatch: 4, identity: 0.84

cttgccgccaccgacccccccttgc	CRISPR spacer
ttttccgacaccgacccccccttga	Protospacer
.** *** **************** 

71. spacer 6.5|2073782|24|NC_021251|CRT matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 4, identity: 0.833

atcgaagaagctgaacccgccgtt	CRISPR spacer
atcgaagaagctgaacacgcccgc	Protospacer
**************** ****  .

72. spacer 6.5|2073782|24|NC_021251|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 4, identity: 0.833

atcgaagaagctgaacccgccgtt	CRISPR spacer
gtcgatgaagctgaacccgccgaa	Protospacer
.**** ****************  

73. spacer 6.5|2073782|24|NC_021251|CRT matches to NZ_CP015007 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence) position: , mismatch: 4, identity: 0.833

atcgaagaagctgaacccgccgtt	CRISPR spacer
atcggagaagctgaacccgcccgg	Protospacer
****.****************   

74. spacer 1.1|364907|27|NC_021251|CRISPRCasFinder matches to LR794124 (Vibrio phage vB_Vc_SrVc9 genome assembly, chromosome: 1) position: , mismatch: 5, identity: 0.815

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
aacgcaccgttgtccacatcaccaatc	Protospacer
********* **********.** .* 

75. spacer 1.1|364907|27|NC_021251|CRISPRCasFinder matches to NC_012662 (Vibrio phage VP93, complete genome) position: , mismatch: 5, identity: 0.815

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
aacgcaccgttgtccacatcaccaatc	Protospacer
********* **********.** .* 

76. spacer 1.7|365303|27|NC_021251|CRISPRCasFinder matches to NZ_CP016084 (Streptomyces sp. SAT1 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.815

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
gcgaagccgaagttgtagctgcgctcg	Protospacer
********** ***********   .*

77. spacer 1.7|365303|27|NC_021251|CRISPRCasFinder matches to MN693945 (Marine virus AFVG_250M952, complete genome) position: , mismatch: 5, identity: 0.815

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
atgaagccgatgttgtcgctaccgggg	Protospacer
..************** ***.**** *

78. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

79. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013525 (Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

80. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013554 (Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

81. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP015368 (Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tccccgcggaagttgaggtcgcgggtg	Protospacer
 ****** ************** *. *

82. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013588 (Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

83. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013560 (Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

84. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013577 (Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

85. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013549 (Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

86. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013529 (Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

87. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013534 (Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

88. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

89. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013545 (Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

90. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP020444 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ****** 

91. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013565 (Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

92. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013582 (Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

93. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP013571 (Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

94. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP044078 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ****** 

95. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP031081 (Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ****** 

96. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to MN586031 (Gordonia phage Gambino, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

97. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to KU998236 (Gordonia phage Blueberry, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

98. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to MN062704 (Gordonia phage JuJu, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

99. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to MK501729 (Gordonia phage Walrus, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

100. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NC_031226 (Gordonia phage BaxterFox, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

101. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to MK967393 (Rhodococcus phage Whack, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tccttaccgaagttgaggtcgacgagg	Protospacer
 **...*************** *****

102. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to MT723935 (Gordonia phage Azula, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

103. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to KU963249 (Gordonia phage Yeezy, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

104. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to MH153808 (Gordonia phage Petra, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

105. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to MT639650 (Gordonia phage Ohgeesy, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

106. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to MH536818 (Gordonia phage Frokostdame, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

107. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to KX557275 (Gordonia phage CarolAnn, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

108. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to NZ_LN907828 (Erwinia gerundensis isolate E_g_EM595 plasmid pEM01, complete sequence) position: , mismatch: 5, identity: 0.821

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gctgccgtgggtgccatcgttgccgagt	Protospacer
*.***** *****************. .

109. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to KU728633 (Mycobacterium phage Bipper, complete genome) position: , mismatch: 5, identity: 0.821

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gcgtccgggggtgccgtcgttgccgtcc	Protospacer
*.  ***********.********* **

110. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to MK977701 (Mycobacterium phage Cracklewink, complete genome) position: , mismatch: 5, identity: 0.821

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gcgtccgggggtgccgtcgttgccgtcc	Protospacer
*.  ***********.********* **

111. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to NZ_CP016354 (Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence) position: , mismatch: 5, identity: 0.821

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gttgccgcgggtgccctcgttgcggacg	Protospacer
******* ******* ******* *.* 

112. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_CP025013 (Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence) position: , mismatch: 5, identity: 0.8

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gccgccgaacacgccgaagccgttt	Protospacer
 ..********************. 

113. spacer 4.5|1574011|25|NC_021251|CRISPRCasFinder matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 5, identity: 0.8

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gttgccgaacacgccgacgccgcgc	Protospacer
 **************** ****.  

114. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NC_018746 (Pseudomonas putida ND6 plasmid pND6-2, complete sequence) position: , mismatch: 5, identity: 0.839

aattg--cgccttgcccgccgttgccgccggca	CRISPR spacer
--ttggccaccttgcacgcccttgccgccggca	Protospacer
  ***  *.****** **** ************

115. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to MN961671 (Pseudomonas aeruginosa strain 201330 plasmid p201330-IMP, complete sequence) position: , mismatch: 5, identity: 0.839

aattg--cgccttgcccgccgttgccgccggca	CRISPR spacer
--ttggccaccttgcacgcccttgccgccggca	Protospacer
  ***  *.****** **** ************

116. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to MN961672 (Pseudomonas aeruginosa strain PA15W plasmid pPA15W-NR, complete sequence) position: , mismatch: 5, identity: 0.839

aattg--cgccttgcccgccgttgccgccggca	CRISPR spacer
--ttggccaccttgcacgcccttgccgccggca	Protospacer
  ***  *.****** **** ************

117. spacer 4.13|1574653|34|NC_021251|CRISPRCasFinder matches to NC_006362 (Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence) position: , mismatch: 5, identity: 0.853

gtcgccgtgcagccagccaccaccgcca-ccggcg	CRISPR spacer
ttcgccgtgcagccggccaccacctccagcctgc-	Protospacer
 *************.********* *** ** ** 

118. spacer 10.7|3739443|31|NC_021251|CRT matches to NC_010850 (Rhodococcus sp. NS1 plasmid pNSL1, complete sequence) position: , mismatch: 5, identity: 0.839

aacgccc-acttcaccgccgttgccgccgtca	CRISPR spacer
-acacccgacttcaccgccgctgccgccgaga	Protospacer
 **.*** ************.********  *

119. spacer 1.1|364907|27|NC_021251|CRISPRCasFinder matches to NZ_CP045917 (Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence) position: , mismatch: 6, identity: 0.778

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
agttcactggtgtccacatcgcccgaa	Protospacer
*.. ***.***************** .

120. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.818

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agcaggtcgatcacgatctggccgttgccggcg	Protospacer
**   *.***** ******************.*

121. spacer 1.7|365303|27|NC_021251|CRISPRCasFinder matches to NZ_CP022542 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence) position: , mismatch: 6, identity: 0.778

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
ggataggcgatgttgtagctgccggaa	Protospacer
* . ** ****************** .

122. spacer 1.9|365453|27|NC_021251|CRISPRCasFinder matches to NC_009959 (Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI05, complete sequence) position: , mismatch: 6, identity: 0.778

gccaagccgatatcgaagatcccggtg	CRISPR spacer
accatgccgatatcgacgatcccgtcc	Protospacer
.*** *********** ******* . 

123. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tagacgccgaagtcgaggtcggcgagg	Protospacer
    *********.******* *****

124. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
ctcccgccgaagttgagggtgccgaac	Protospacer
 .**************** .*****. 

125. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
aagaagccgaagttgaggtcgccgtag	Protospacer
*    ******************* .*

126. spacer 1.10|365513|27|NC_021251|CRISPRCasFinder matches to MK494099 (Mycobacterium phage Typha, complete genome) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
cggtcgccgaggtcgaggtcgccgagg	Protospacer
   .******.**.*************

127. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
gcgccgccggtgactacgccgccagcgaca	Protospacer
.*  **********.*********.****.

128. spacer 2.2|629731|30|NC_021251|CRT matches to KX620751 (Propionibacterium phage Doucette, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
gagactccggtgaccacgccgccatcgatg	Protospacer
.  ** ****************** ***.*

129. spacer 2.2|629731|30|NC_021251|CRT matches to NC_041891 (Propionibacterium phage B22, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
gagactccggtgaccacgccgccatcgatg	Protospacer
.  ** ****************** ***.*

130. spacer 2.2|629731|30|NC_021251|CRT matches to NC_041894 (Propionibacterium phage E6, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
gagactccggtgaccacgccgccatcgatg	Protospacer
.  ** ****************** ***.*

131. spacer 2.2|629731|30|NC_021251|CRT matches to KX620754 (Propionibacterium phage G4, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
gagactccggtgaccacgccgccatcgatg	Protospacer
.  ** ****************** ***.*

132. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP030127 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
tccacgccggtgaccacgccgaccaccttg	Protospacer
 ******************** * **  .*

133. spacer 2.2|629731|30|NC_021251|CRT matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
aagaggccggcgagcacgccgccaacgaag	Protospacer
*  * *****.** ************** *

134. spacer 2.2|629731|30|NC_021251|CRT matches to MT818419 (Mycobacterium phage Lolalove, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
atcgaggcggtgaccacgccgccgccgacg	Protospacer
*.*. * ****************. *****

135. spacer 2.2|629731|30|NC_021251|CRT matches to MN428050 (Mycobacterium phage Apex, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
atcgaggcggtgaccacgccgccgccgacg	Protospacer
*.*. * ****************. *****

136. spacer 2.2|629731|30|NC_021251|CRT matches to MN234171 (Mycobacterium phage Magpie, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
atcgaggcggtgaccacgccgccgccgacg	Protospacer
*.*. * ****************. *****

137. spacer 2.2|629731|30|NC_021251|CRT matches to KX589269 (Mycobacterium phage Fortunato, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
atcgaggcggtgaccacgccgccgccgacg	Protospacer
*.*. * ****************. *****

138. spacer 2.2|629731|30|NC_021251|CRT matches to NC_042035 (Mycobacterium phage Zemanar, complete sequence) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
atcgaggcggtgaccacgccgccgccgacg	Protospacer
*.*. * ****************. *****

139. spacer 2.2|629731|30|NC_021251|CRT matches to NC_022331 (Mycobacterium phage Bane1, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
atcgaggcggtgaccacgccgccgccgacg	Protospacer
*.*. * ****************. *****

140. spacer 2.2|629731|30|NC_021251|CRT matches to KF279413 (Mycobacterium phage Bane2, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
atcgaggcggtgaccacgccgccgccgacg	Protospacer
*.*. * ****************. *****

141. spacer 2.2|629731|30|NC_021251|CRT matches to MT310870 (Mycobacterium phage RawrgerThat, complete genome) position: , mismatch: 6, identity: 0.8

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
atcgaggcggtgaccacgccgccgccgacg	Protospacer
*.*. * ****************. *****

142. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to GQ141189 (Bifidobacterium phage Bbif-1, complete sequence) position: , mismatch: 6, identity: 0.806

agcgcgaacggcaagccgaac----cgttggaccc	CRISPR spacer
agcgcgaacggccagccgaaccatgcgctgg----	Protospacer
************ ********    **.***    

143. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to NZ_AP022571 (Mycolicibacterium poriferae strain JCM 12603 plasmid pJCM12603, complete sequence) position: , mismatch: 6, identity: 0.786

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
ggtgccgggggtggcaccgttgccgcgg	Protospacer
* *********** **.********   

144. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to NC_008703 (Mycobacterium sp. KMS plasmid pMKMS01, complete sequence) position: , mismatch: 6, identity: 0.786

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
ggtgccgggggtggcaccgttgccgcgg	Protospacer
* *********** **.********   

145. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to NZ_LR594663 (Variovorax sp. RA8 plasmid 2) position: , mismatch: 6, identity: 0.786

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
ggtgccggcggtgccatcggtgccgagg	Protospacer
* ****** ********** *****.  

146. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_LR594669 (Variovorax sp. SRS16 plasmid 4) position: , mismatch: 6, identity: 0.806

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ccttgcgccttgcccgccgctgccgcagggc	Protospacer
  *****************.****** **  

147. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 6, identity: 0.806

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ccttgcgccttgcccgccgctgccgcagggc	Protospacer
  *****************.****** **  

148. spacer 4.13|1574653|34|NC_021251|CRISPRCasFinder matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 6, identity: 0.824

--gtcgccgtgcagccagccaccaccgccaccggcg	CRISPR spacer
ctgtcgtc--gcagcgcgccaccaccgccaccggca	Protospacer
  ****.*  *****  ******************.

149. spacer 10.7|3739443|31|NC_021251|CRT matches to NC_009478 (Clavibacter michiganensis subsp. michiganensis NCPPB 382 plasmid pCM1, complete sequence) position: , mismatch: 6, identity: 0.806

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgaccacttcaccgccgtcgccgccggcg	Protospacer
. ** ***************.******* *.

150. spacer 12.12|3934661|30|NC_021251|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.8

gcggtgggcagcgtcggtaacgccgggatc	CRISPR spacer
ccggtgggcatcgtcggtgacgccggacgc	Protospacer
 ********* *******.*******.  *

151. spacer 1.4|365102|27|NC_021251|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.741

aagccgcccgagttcgcgagaccgaag	CRISPR spacer
tgaccgcccgagttcgcgagacgttgg	Protospacer
 ..*******************   .*

152. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
taggcgccggtgaccccgccgccgacgatg	Protospacer
   .*********** *******.****.*

153. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
tgcgtggcggtgaccacgccgccaatggcg	Protospacer
  *..* ******************.*.**

154. spacer 2.2|629731|30|NC_021251|CRT matches to LR134127 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 7) position: , mismatch: 7, identity: 0.767

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
atagcgccggtcaccgcgccgccaacgata	Protospacer
*. .******* ***.************..

155. spacer 2.2|629731|30|NC_021251|CRT matches to NC_005241 (Cupriavidus necator H16 megaplasmid pHG1, complete sequence) position: , mismatch: 7, identity: 0.767

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
acctcgtcggtgaccacgccgccgtgcagg	Protospacer
*** **.****************.   * *

156. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
accacgccggtgacctcaccgcccgctgtg	Protospacer
*************** *.***** .* ..*

157. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP012478 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
accacgccggtgacctcaccgcccgctgtg	Protospacer
*************** *.***** .* ..*

158. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP039289 (Cupriavidus necator H16 plasmid pHG1, complete sequence) position: , mismatch: 7, identity: 0.767

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
acctcgtcggtgaccacgccgccgtgcagg	Protospacer
*** **.****************.   * *

159. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP014600 (Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
ccggcgccggtgaccgcgccgccaaggcag	Protospacer
 * .***********.********* *  *

160. spacer 2.2|629731|30|NC_021251|CRT matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 7, identity: 0.767

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
ggcccgccgatggccacgccgccaacggca	Protospacer
. * *****.**.**************.*.

161. spacer 2.2|629731|30|NC_021251|CRT matches to NC_042034 (Mycobacterium phage ChrisnMich, complete sequence) position: , mismatch: 7, identity: 0.767

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
gtcgaggcggtgaccacgccgccgccgacg	Protospacer
..*. * ****************. *****

162. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MK977708 (Mycobacterium phage Fulbright, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

163. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MG099948 (Mycobacterium phage Philonius, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

164. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MH926055 (Mycobacterium phage Chewbacca, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

165. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MT723932 (Mycobacterium phage Schnauzer, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

166. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to KU935726 (Mycobacterium phage Xerxes, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

167. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to KU935730 (Mycobacterium phage Pipsqueaks, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

168. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MH316570 (Mycobacterium phage Silvafighter, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

169. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MK524518 (Mycobacterium phage Smurph, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

170. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MK524515 (Mycobacterium phage Parmesanjohn, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

171. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MH697585 (Mycobacterium phage Gex, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

172. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to KM588359 (Mycobacterium phage Carcharodon, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

173. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MH697576 (Mycobacterium phage Aggie, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

174. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MH697593 (Mycobacterium phage Tapioca, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

175. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to MG099936 (Mycobacterium phage Andies, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

176. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to NC_031243 (Mycobacterium phage Xeno, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

177. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to JN256079 (Mycobacterium phage Charlie, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

178. spacer 4.1|1573789|28|NC_021251|CRISPRCasFinder matches to NC_010553 (Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence) position: , mismatch: 7, identity: 0.75

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
agcacccggggtgccgtcgttgccggcg	Protospacer
. ..** ********.*********** 

179. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP041045 (Paracoccus sp. AK26 plasmid pAK1, complete sequence) position: , mismatch: 7, identity: 0.774

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gttgccgccatgcccgccgctgccgccggcc	Protospacer
. *  **** *********.********** 

180. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to CP017041 (Propionibacterium sp. oral taxon 193 strain F0672 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
aacggcgtcttgcccgccgtggccgccaccg	Protospacer
**. ***.************ ******. *.

181. spacer 6.3|2073692|30|NC_021251|CRT matches to NZ_CP015065 (Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence) position: , mismatch: 7, identity: 0.767

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ttcggtaaagccgtcggtgtgcacgctgac	Protospacer
*. *. ************ ********* .

182. spacer 6.3|2073692|30|NC_021251|CRT matches to NZ_CP015063 (Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence) position: , mismatch: 7, identity: 0.767

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ttcggtaaagccgtcggtgtgcacgctgac	Protospacer
*. *. ************ ********* .

183. spacer 6.3|2073692|30|NC_021251|CRT matches to NC_014918 (Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence) position: , mismatch: 7, identity: 0.767

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ttcggtaaagccgtcggtgtgcacgctgac	Protospacer
*. *. ************ ********* .

184. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cccacccacttcaccgacgtcgccgccgacg	Protospacer
  *.************ ***.******* *.

185. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP012186 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cccacccacttcaccgacgtcgccgccgacg	Protospacer
  *.************ ***.******* *.

186. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP042263 (Litoreibacter sp. LN3S51 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
atccgccatttcaccgccgttgccgacgccg	Protospacer
* *  ***.**************** **.*.

187. spacer 12.12|3934661|30|NC_021251|CRT matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 7, identity: 0.767

gcggtgggcagcgtcggtaacgccgggatc	CRISPR spacer
gatcagagaagcgacggtaacgccgggatc	Protospacer
*    *.* **** ****************

188. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttggtgtcgatctcgatctggccgttgcccgca	Protospacer
  * **.*****.**************** *..

189. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agctggttgatgccgatctggccgctgccggtc	Protospacer
** . *..*** ************.******* 

190. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
atgctgccgaccccgatctggtcgttttcgact	Protospacer
* ********.**********.**** .**.. 

191. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to CP007644 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtcgaccttc	Protospacer
 ***************** ** ***.* *  * 

192. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agctggttgatgccgatctggccgctgccggtc	Protospacer
** . *..*** ************.******* 

193. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP045074 (Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
cagacctcggtgaccacgccggcaacgatc	Protospacer
   ** .************** ******. 

194. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP015269 (Mycobacterium chimaera strain ZUERICH-2 plasmid unnamed 2, complete sequence) position: , mismatch: 8, identity: 0.733

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
ggttggccggtgaccactccgccagcgatg	Protospacer
. .  ************ ******.***.*

195. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gcgggcgccttgtccgccgctgccgccgggc	Protospacer
.   ********.******.*********  

196. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP039899 (Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

197. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP039913 (Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625b, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

198. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP039890 (Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

199. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP018001 (Rhizobium sp. Y9 plasmid pY9, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

200. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NC_022536 (Rhizobium sp. IRBG74 plasmid IRBL74_p, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

201. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP053858 (Rhizobium pusense strain 76 plasmid pR76, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

202. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gcgagcgccttgcccgccgtggtcgccgccc	Protospacer
.   **************** *.***** * 

203. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to CP036360 (Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

204. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP021914 (Sagittula sp. P11 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

aattgc--gccttgcccgccgttgccgccggca	CRISPR spacer
--ccgctggccttgcccggggttgccgccgggg	Protospacer
  ..**  **********  *********** .

205. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
attgccgccctggccgccgttgccgccgatc	Protospacer
* *  ****.** ***************.. 

206. spacer 6.3|2073692|30|NC_021251|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.733

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ccgcgagcagccgtcggtttgcgcgctgtc	Protospacer
.** ... **************.******.

207. spacer 6.3|2073692|30|NC_021251|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.733

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ccgcgagcagccgtcggtttgcgcgctgtc	Protospacer
.** ... **************.******.

208. spacer 10.7|3739443|31|NC_021251|CRT matches to CP033373 (Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
ttagcccacttcacggccgttgccgacgcgg	Protospacer
   *********** ********** **. .

209. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

210. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

211. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

212. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

213. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

214. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

215. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

216. spacer 10.7|3739443|31|NC_021251|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

217. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

218. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cgcaactccttcaccgccgctgccgccgtct	Protospacer
 .*. *. ***********.********** 

219. spacer 10.7|3739443|31|NC_021251|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

220. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

221. spacer 10.7|3739443|31|NC_021251|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

222. spacer 10.7|3739443|31|NC_021251|CRT matches to NZ_CP027299 (Streptomyces sp. SGAir0924 plasmid unnamed_5) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
ctcggtggcttcgccgccgtcgccgccgtca	Protospacer
  ** . .****.*******.**********

223. spacer 10.7|3739443|31|NC_021251|CRT matches to NC_014213 (Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
atcgcccacttcaccggcgtttccgaccctt	Protospacer
* ************** **** *** * .. 

224. spacer 12.9|3934430|39|NC_021251|CRT matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.795

gccggt-ggcgccggcggggccggcgggcagggcggtagc	CRISPR spacer
-ctgatcggcgccggcggggccgccggccagggcgatgcc	Protospacer
 *.*.* **************** *** *******.*. *

225. spacer 12.12|3934661|30|NC_021251|CRT matches to NZ_CP048385 (Citrobacter freundii strain 62 plasmid p6_C, complete sequence) position: , mismatch: 8, identity: 0.733

gcggtgggcagcgtcggtaacgccgggatc	CRISPR spacer
gcggtgagcagcgtcggtagcgcgccaacg	Protospacer
******.************.***   .*. 

226. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtattcgatcccgatctggccgtcgccggcc	Protospacer
  *.  .******************.*****. 

227. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  * 

228. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  * 

229. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP048281 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  * 

230. spacer 2.2|629731|30|NC_021251|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

accacgccggtgaccacgccgccaacgacg	CRISPR spacer
cccacgccggtcaccacgccgctgcccggc	Protospacer
 ********** **********.. * .  

231. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to NZ_CP014964 (Geobacter anodireducens strain SD-1 plasmid pSD, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
ggaacgaacggcaagccgaaatgttggtgga	Protospacer
.* .**************** .*****    

232. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to NC_015974 (Sphingobium sp. SYK-6 plasmid pSLPG, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
taagcgaacggtaagccgaaccgctgaggcg	Protospacer
 . ********.***********.**.. * 

233. spacer 3.1|690438|31|NC_021251|CRISPRCasFinder matches to NZ_CP005085 (Sphingobium sp. TKS plasmid pTK1, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
taagcgaacggtaagccgaaccgctgaggcg	Protospacer
 . ********.***********.**.. * 

234. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcctcgccctgcccgccgttgccgcccacg	Protospacer
.... ****.***************** .*.

235. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
tggcccgccttgccctccattgccgccggac	Protospacer
 . . ********** **.**********  

236. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NC_022049 (Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
atccttgccttgaccgccgttgccgccgctg	Protospacer
* .. .****** *************** ..

237. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to MN234199 (Mycobacterium phage Ekdilam, complete genome) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
accccagccctgcccgccgttgccgccgctc	Protospacer
* ..  ***.****************** . 

238. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP023000 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gcttgcgcctggcccgccgtagccggacacc	Protospacer
. ******** ********* ****   .* 

239. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP015737 (Shinella sp. HZN7 plasmid pShin-01, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
accggcaccttgcccgccattgccgccatgt	Protospacer
* . **.***********.********.   

240. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP013740 (Streptomyces globisporus C-1027 plasmid pSGL1, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
cgggccgccttgtccgccgtggccgccgacc	Protospacer
 .   *******.******* *******.* 

241. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
agcgtggccttggccgccgttgccggcggtc	Protospacer
*..   ****** ************ ***. 

242. spacer 10.5|3739302|34|NC_021251|CRT matches to NZ_CP021805 (Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.735

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
attgagatccgcgacgatgggtgtggcgccggcg	Protospacer
.**    .********.**** ***********.

243. spacer 10.5|3739302|34|NC_021251|CRT matches to MG812496 (Gordonia phage SallySpecial, complete genome) position: , mismatch: 9, identity: 0.735

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gcgcaccaccgcggcggtgcgggtggcgccggcg	Protospacer
*. . *. *****.***** *************.

244. spacer 10.9|3739575|37|NC_021251|CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.757

cttgccggcggtgccggcgaccgcggtgccgccggcg	CRISPR spacer
ggagacggcggtgccggagaccgcggtgtcgctgccc	Protospacer
   * ************ **********.***.* * 

245. spacer 12.9|3934430|39|NC_021251|CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 9, identity: 0.769

gccggt-ggcgccggcggggccggcgggcagggcggtagc	CRISPR spacer
-ctgatcggcgccggcggggccgccggccagggcgacgcc	Protospacer
 *.*.* **************** *** *******... *

246. spacer 12.9|3934430|39|NC_021251|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 9, identity: 0.769

gccggt-ggcgccggcggggccggcgggcagggcggtagc	CRISPR spacer
-ctgatcggcgccggcggggccgccggccagggcgacgcc	Protospacer
 *.*.* **************** *** *******... *

247. spacer 12.9|3934430|39|NC_021251|CRT matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.769

gccggtggcgccggcggggccggcgggcagggcggtagc	CRISPR spacer
ggcccgggcgacggcggggccgtcgggcagggcgctccc	Protospacer
* *   **** *********** *********** *  *

248. spacer 12.12|3934661|30|NC_021251|CRT matches to NC_012725 (Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence) position: , mismatch: 9, identity: 0.7

gcggtgggcagcgtcggtaacgccgggatc	CRISPR spacer
gatttgggcagagtcggtaacgccgaatgg	Protospacer
*   ******* *************..   

249. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtactcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****. 

250. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtactcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****. 

251. spacer 1.6|365237|33|NC_021251|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtattcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****. 

252. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 10, identity: 0.677

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gggctcgcctcgcccgccgttcccgccgctc	Protospacer
.. . *****.********** ****** . 

253. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.677

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ttcctcgccttccccgccgctgccgccgcgg	Protospacer
  .. ****** *******.********  .

254. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 10, identity: 0.677

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggccagaacttccccgctgttgccgccggca	Protospacer
..... . *** *****.*************

255. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NC_017590 (Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence) position: , mismatch: 10, identity: 0.677

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gggctcgcctcgcccgccgttcccgccgctc	Protospacer
.. . *****.********** ****** . 

256. spacer 4.10|1574404|31|NC_021251|CRISPRCasFinder matches to NZ_AP014581 (Burkholderia sp. RPE67 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.677

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcgtggccttggccgccgttgccggcggtc	Protospacer
...   ****** ************ ***. 

257. spacer 4.13|1574653|34|NC_021251|CRISPRCasFinder matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 10, identity: 0.706

gtcgccgtgcagccagccaccaccgccaccggcg	CRISPR spacer
ccgatgatgcagccggccaccaccgccaccagca	Protospacer
 . .. .*******.***************.**.

258. spacer 8.9|3114598|35|NC_021251|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 10, identity: 0.714

acttgcgcgcacaacgcatccgccatccacggggc	CRISPR spacer
gtcaccgcgcacaacacattcgccatccacacggt	Protospacer
...  **********.***.**********. **.

259. spacer 10.5|3739302|34|NC_021251|CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
cagcgcggccgcgtcggtgggggtggcgcccgcc	Protospacer
   . *  ***** **************** ** 

260. spacer 10.5|3739302|34|NC_021251|CRT matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.  

261. spacer 10.5|3739302|34|NC_021251|CRT matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.  

262. spacer 10.5|3739302|34|NC_021251|CRT matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.  

263. spacer 10.5|3739302|34|NC_021251|CRT matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 11, identity: 0.676

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
cgcccccggcgtgacggtggaggtggcgccggcc	Protospacer
  ...*.  **.********.************ 

264. spacer 10.9|3739575|37|NC_021251|CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.703

cttgccggcggtgccggcgaccgcggtgccgccggcg	CRISPR spacer
gccgtgcacggcgccggcggccgcggtgccgccgctg	Protospacer
 ..*.  .***.*******.************** .*

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2935721 : 2973994	47	Mycobacterium_phage(30.0%)	head,terminase,integrase,protease,tRNA,capsid	attL 2964523:2964550|attR 2974147:2974174
DBSCAN-SWA_2	3706703 : 3796139	57	Burkholderia_virus(28.57%)	tRNA,transposase	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_021251|2935721:2973994|DBSCAN-SWA
GTCACTCACGACCGGCCACTTTCACCAGTTCCGCTGTAGGAACCGCATTTTCGCGGTCAGCGATCCAGGCGACAATGGCCGCCACCGCATCGTCACGGGCCACACCGTTGATTTGGGTGCGGTCACCGAACCGGAAACTCACCGCGCCGGCGGCGACGTCACGATCACCCGCCAACACCATGAACGGCACCTTGTGGTTGGTGTGGTGCACGATCTTCTTGGCCATCCGATCGTCGCTGGCGTCCACCTCGGCCCGCACCCCGTGCGACTTCAGTTGCGTGGCAACCTCTTCCAGATAGGCGACGTGCTCATCGGCGACCGGGATGCCGACCACCTGCACGGGCGCCAACCAGGCCGGGAACGCCCCCGCGTAGTGCTCGGTGAGAATGCCGAAGAACCGCTCGATCGACCCAAATAGCGCGCGGTGGATCATCACCGGGCGGTGGCGGGTTCCGTCGGCGGCGGTGTACTCCAGGCCGAAACGTTCCGGAAAGTTGAAGTCCAGCTGGATGGTCGACATCTGCCAGGTGCGGCCCAGCGCGTCTTTGACCTGCACTGAAATCTTGGGCCCGTAGAACGCCGCGCCGCCTGGATCGGGCACCAGCTCCAGCCCGGATTCGGCGCCCACCTCGGCCAGCACGGTGGTGGCTTCCTCCCAGACCTCCTCGGCGCCGACGAACTTCTCCGGGTCCTTGGTGGACAGTTCGAGGTAGAAGTCGGTGAGGCCGTAGTCGGCGAGCAGGTCGAGCACAAACCGCAGCAGCGACCGCAGCTCGTCGCGCATCTGGTCGCGGGTGCAGAAGATGTGCGCGTCGTCCATGGTCAGCCCACGCACCCGGGTCAACCCGTGCACCACACCGGACTTCTCGTAGCGATACACCGTGCCGAACTCGAAGAGCCGCAACGGCAGTTCCCGATAGGATCGCCCGCGCGCGCGGAAGATCAGGCAGTGCATCGGGCAGTTCATCGGCTTGAGGTAGTAGTCCTGGCCGGGTTTGCGCAGCGAGCCGTCGGCGTTGTACTCCGCGTCGATGTGCATCGGGGGGAACATGCCGTCGGCGTACCAGTCCAGATGTCCCGAGGTGTGGAACAACTGGGCCTTGGTGATGTGCGGGCTGTTGACGAACTGGTAGCCCGCCTCGGTGTGCTTGCGCCGCGAGTAGTCCTCCAGTTCGCGACGCACGATGCCGCCCTTGGGGTGGAAAACCGCTAGGCCGGAACCGATTTCGTCGGGGAAGCTGAACAGGTCCAGCTCGACACCCAGCTTGCGGTGGTCGCGGCGCTGCGCCTCTTCGATGAACTCCAGGTGCCTGTCGAGCGCCTCCTGGGATTCCCACGCGGTGCCGTAGATCCGTTGCAGGCTGGCGTTTTTCTGATCGCCCCGCCAGTAGGCGGCCGAGCTGCGGGTGAGCTTGAACGCCGGGATGTGTTTGGTGGTCGGGATGTGCGGTCCGCGGCACAGGTCGCCCCAGACGCGCTCGCGGGTGCGGGGGTTGAGGTTGTCGTAGGCGGTGAGCTCGTCACCGCCGACCTCCATGATCTCGGCGTCACCCGATTTGTCGTCGACGAGTTCCAGCTTGTAGGGCTCGTTGGCCAGCTCGGCGCGGGCCTGTTCGGTGGATTCGTAGACCCGCCGGTCGAACAGCTGGCCTTCCTTGACGATCTGGCGCATCCGCTTTTCCAGCGCCGCCAAGTCCTCGGGCGTGAACGGCTCGGGCACGTCGAAGTCGTAGTAGAAGCCGTCGGTGATGGGTGGTCCGATGCCGAGCTTGGCCTGCGGAAACAGCTCTTGGACGGCTTGGGCCAACACGTGCGCGGTCGAATGGCGGATCACGCTGCGACCGTCGTCGGTGTTGGCGGCCACCGGCGTGATATCGGTGTCGACGTCGGGCACCCAGCTCAGGTCGCGCAGGTTGCCGTCGGCGTCGCGCACGACGACGATCGCATCGGGCGTACCGCGCCGCGGTAAACCCGCTTCGCCGACGGCGGTGGCCGCGGTGGTCCCGGCAGGAACCCGAATTCGGGCTTGCGACGGGTCGCCGCCATCGACTCCCGGGGCAGGTTGTGCGGGGGCGCTCATCGGGTCGGTCTCCAAGGCTTGGACGTGTCGAAACGATCGCGACCATGCTATCGGGGCGCACGTCGACGACCGTAAGCCGAGTGACCGGATGGGTTTTCGATCACCGGTGTGGGCGATCGGTACCGGGCAGGTGACCGGGTGCTCTACGGCGGCTCGATGAGCCCAAAGGATGTTGACGACCTGGCTACCCAGCAGGACGTCGACGACGGACAGTCGATAGAGCGTCGCTGGACGGGGAGCGGTCAGCGACGCTGGCGGCGGTCGCCGCCGACGGGCCGCTACCGTAGCAACTCGCAAATCCAGGTCTGGATTTCCGGCGCCGGCCGGCTCCGTTAGCCGTCGGCTCCGTTGGTGCCGGCCAGGCCGGGTGGCCCCAACAGTGATGCACCGCCGCTGCCGCCGGGCCCGCCGAAGCCTGGAGCGCCATTGAAGAGGCTCCCGGCGCCGCCGTTTCCGCCGTTTCCACCGTTGCCGATCAGTCCGACGCTGCCGCCGTTCCCGCCTTTCCCGCCGTCACCGCCGGACCCGCCAGCAGTGCCGGCGCTCGCTCCGTTCCCGCCGGCCCCGGCGCTCCCACCGGCCCCCGCGTTGCCGATGAGGGCATTGCCGCCGTTTCCACCGCTGCCGCCGCTACCGCCATTCCCTCCGAAGGCCGTAACAGACCCGGGCGACCCGGCGGCACCGCCGTTTCCGCCGGCCCCGCCGTTACCGTAGAGTAGCCCGCCGGCGCCGCCGTTACCGCCTTGCCCGCCAAACCCAACGCCCCCGAAATCGGCGGACACATCACCACCGGCTCCGCCGGCTCCGCCATTGCCGCCGTTGCCGATCAGTCCGGTGGTTCCGGCGTGACCACCGTTACCCCCGAATCCGGACGCTGGACCGTTCTGAGAAATGCCTGCCCCGTTTCCGGCGGCCCCGCCGTCCCCGCTGTTGCCGATCAGTAGGCCGCCGTTCCCGCCGTTCCCGCCGTTGCCGCCGCTAGCCCCCGCGGAGGGCTCGCCGCCGCCGGTGCCCCCGGCCCCGCCGGTCCCGCCGGCGCCGATCAGCCCGGCGTTGCCGCCGTTCCCACCATGCCCGCCGATAGCGAGGTTGGTGCCGGCCCCACCGATCCCGCCGTTCCCGCCGGCCCCGCCGTTGCCGAACAGCCATCCACCGGCGCCGCCGGCTCCGCCGTTCGCGCCGGCCTCAAAGGGTAGGCCCTGGCCGCCAGCTCCGCCGGCCCCACCGTTGCCGATCAACCCGGCCGCCCCGCCGGCGCCGCCGGCCTGCCCGGGTGCCCCCGACCCGCCGTTGCCGCCGTTGCCCCACAGCCACCCGCCGTTACCGCCGGCTTGCCCGGTCCCGTCGATCCCGTTCGCGCCGTCGCCGATCAATGGGCGCCCGGTCAGCGACTGAACGGGTGCGTTGATCGCATCGAGCACGTTCTGCAGCGGTGTTGCGCTGGCCGCTTCGGCGACCGCGTAGGTGCTGCCAGCTTGGCTTAAGGCCAGCACGAACCGTTCCTGGTAGGCCGCGACCTGCGCGCTGATCGCTTGATAGTGCTGGCCGTGGCTGCCGAACAGCGCGGCGATCGCCGTTGACACCTCGTCTTGGGCGGCGGCCAACACCTGGGTGGTCGCCGCCGCCGCGGTGTTGGCGGTGTTGATCGCCGAGCCGATCCGCGCTGCATCGGCCGCGGCTGTGGACACTAACTGTGGGGCCACGTTGACAAACGACATCGAAATCCTCCTGACCGCCACGATGTTGAGATGCGGGCGGCCCACCGCCTGTTACCGCCGCGGTGGGTAACCGTTTATTCGGACGATCCCTGCCGTTCCACGCCTGGGCGCAGGCACAAACCGCACCAACATTGGTGGAACGTGGTGCACACTGCACCTGGGGTTCTGCCCTCATCGTGTGGCAGCAGGCGAAACCCGCGCGGACGAGAACTCTTCCGCCAAGCAGCACAAATCGCCCTACACCCCAGTGAATCTCCGGACGCCACTACGACAGCGCGCAACGGTCGCCTCATCGACTGTGTGCACGCGCGCTTCGCGATGCGCTGCCGTGGCAAGCTGGCCAGGTGGACCTCAATGCGCTGGCCGATCTGCCGCTGACCTATCCGGAGGTGGGCGCGACAGCGACCGGACGACTGCCCGCGGGCTACAACCACCTTGACGTGTCGACGCAGATCGGCACCGGCCGCCAGCGTTTTGAGCAGGCCGCCGACGCCGTCATGCATTGGGGCATGCAGCGCAACGCCGGCCTGCGGGTGCGGGCCAGCTCCGAAACCGCCGTCGTGTCCGCGGTGGTGTTGGTGGGAATCGCTTTCCTGCGTGCGCCGTGCCGAGTGGTGTATGTCATCGACGAACCCGACGTGCGCGGATTCGGTTACGGCACTTTGCCGGGCCATCCGGTGTCCGGCGAGGAACGGTTCGCGGTTCGCTGCGACCCGATGACCTCCGTGGTGTTTGCCGAGGTGTTGTCGTTCTCCCGTCCGGCGACCTGGGCGAGCAAAGCCGCCGGGCCGCTGGGCGCGGTGACCCAGCGCTTCATCGCCCAGCGCTACCTGCGCGCGGTGTGAGGCGCCGGCGCCCTGGTTAAGGCCGCCCGATGCCTCCGCTGTGCACGCCCTGCGCCAGCCGGGCGAGCGCGATGGCGCCAACCAGCAAACCGAAGTCGCGCAGCGCGATGTCGTAGAAACCGGGTCCGGTGACCAGGTTGAGAATGATCCCGGCCAGCCAGGCCGCGACTACCCAGGCGCCGATGCGCGGTGCGACCGCAACCAATACGCCGGCCACAATCTCGATTGCCCCGACCAAGTACATGCATTGGTCGGCGGTGCCGGGCACGAGATCGTTGATCCAGCCGGCCAGATACATGTTCCAGTGCTGCGGATGGGTCAGCAGATTGAAGAACTTGTCCAGCCCGAACAGGATGGGCGCGACCGTGAACAGCGTGCGAAGCAATACGTATGCAGAGTATGCCGGATCCTTCAGCTGGTCTGCGAGAGCAGGGCTGGTCGTTGGTCTGATGCTCATAGCTGCCTCCCGACTTCTAACAGACAACAATTTGAACGTTAGATCCTATAGACTGTATCGTCAAGTGTTTTGTCTGTTAGAGATGGCTTGCTGAAGTGGACGGCCGAGCTTCCTTCGAACGCGACGTCGCCGGGATCGGGGCACTCGTGGATCCGGTGCGTCGCCAGCTCTACCAATTCGTGTGCTCACAATCGATGCCGGTGAGCCGAGACCAGGCGGCCGACGCCGTCGGCATCCCGCGCCACCAGGCGAAATTCCATTTGGACCGGCTCACTGCCGAAGGCCTGCTGGATACCGAGTACGCGCGCCTGACCGGCCGGTCCGGCCCCGGCGCCGGGCGGACCGCCAAGCTGTATCGCCGGGCCGGCCGCGACATCGCCCTCAGCCTTCCACAGCGGGAGTACGAGCTTGCTGGGCGGCTGATGGCCGCAGCCATCGTGCTGTCGGCCACCACCGGGGAGCCGACCGTGGAAGTGCTCAACCGGATCGCCCATGACTACGGCCAAGCCATGGGCGCCGCCGCCACCACCCGGCCGCCCGCAGACCCCGCGGCGGCGCTGGAGCTGACGCTGGATGTGCTGCGCAAGTACGGTTATGAACCCCGCCGCCCGGCTGGCCCTGGCGACGATGAGGTCGAGCTGGTGAACTGCCCGTTCCACGCACTGGCCCGGGAGCAGACCGAGCTGGCCTGCAATATGAACCACGCCTTGATCACAGGCGTGGCCGACGCGCTGGCACCGCACAGCCCGGCCGTTCGGTTGGCACCCGGACCGGCCCGGTGTTGTGTAGTACTCAAGCGATGTTCGGCTCACGACCCCGAGTGAGCATCGGGCAGGGATTTCAGCACGGTCAGCATGATCACCGAATCCTCGACGGCGTGCAGCGCATGCCGTGTCGGCGGAATCGCGACGTAGTCGCCGGCCCTGCCGTTCCACGCGTCCTCACCGGCGGTAAGGCACACATGGCCCTGCAGCACTTGCAGCGTCGCCTCGCCCGGGCTGTCATGCTCGGACAGGTCGTGGCCGGCAAGCAATGCCAGCACCGTCTGCCGAAGCTCGTGGGTGTGACCACCGTGGATGGTGTGGGCAGCCCGTCCGCTGTGTGTCTGTTGCGCCTCGGCCAGCTTTTCGGCGGCCAGGCTGGTCAGCGAAATGGATTCCATCGGCGCGTCCTTTCAGCCGTTCAGTAGCAGTATCCCCGCGACGAGCAACGCAACCACCTTGACTATCTCCAAACCGACATAGATGTGGTGACCGCGGGAGCGGGGAGCCTGCAGCCCGGCCAATACCTGATTGGACCGTCGAGTCAATCGAGGACGCACCGCAATCAACTGGACGGCCAACGCAGCCAACGCGACCGAAAACGCCGCGGCGATCCGCGCCGGCGTCGAGCCGACCACCACGATCGCGAGGATGACAAGGGCGAAACCGACCTCAACGGTATTGAGCGCACGGAAGACCAACCGGCCGATGCCGAGCCCGATCTGCAGCGTCACTCCTGCCGCCCGGAACTTCAGCGGAGCTTCCAGAAACGAGATCGCCACCACCATTCCCAGCCAGACGAACGCGACGGCGACCTCGATCGCCGGTCCGGCGCTCACCGAATGGCTCCTTCCAGCGGCGTGAAGTGGGCCAGGCACAGGTCGGGTTCGACGAACGCGTCGAGCCGGTCGACGGTGACTGGCGCCCCCCATGTTTGCAAGGCTCCCCGCATGATCCCTAAGTGGACGGGGCAGACGACACCGGCTTGAGTTTCGGCGAGTTCCAGAAACGGACAGTGCCGCAGACCGACCTGTTGCCTGCCGTTGGATGCCCGGCGCTCGGGAGCGAAGCCAAGGTCGTCAAGCACCGCGACCAAGTGGTCGATCGTCTCCTCGGTGTCGGCACCGGCCGGCGGCGCTTCGAGCTGGCGCCCCCACGCCCGGCCCGCGGACAACGCCATGACCCGCGAATCCCGTTCGGCGGCAAGGCCACTGGCGAGGATCTCGGCAAGCAGCCGGTAACGCCGCGTCCCAGTGCTATCCGTCCGCCGGACCGCCCGAAACATCAGCGGCGGGCGCCCCGGTCGGCCGCGGCCGGGCTCGACCCGCTCCACCTGGCCATCAGCGACCAGGTTATCGAGGTGGAAGCGGACGGTGTTGGGATGCACGCCCAACTTGCCGGCGATCGCGGCGATGCTCATCGGAACCCGCGACGCACACAATGCCCGCAGCACCGCACGACGGCGCCCCACCGGCTCTTGCAGTGACCTGATGATGACACTCACCCCCATAAGGCTCGTCGGCTGCGCCTGAGCAATGCAGTAAGTTTACACAAACGGACTTGTAAAAACCTGCGGAGGTGGGGTCTATGGCCAACAAACGTGGCAATGCCGGGCAGCCTCTGCCCTTGTCGGATCGAGACGACGACCACATGCAGGGGCACTGGCTGCTGGCCCGGCTGGGCAAGCGGGTGCTGCGTCCCGGCGGCGTCGAACTCACCCGGACACTGCTGGCCCGCGCCGAGGTGACCGACGCCGACGTGCTCGAGCTGGCACCGGGCCTGGGCCGCACCGCAGCCGAAATCTTGGCCCGCAACCCGCGGTCGTACGTGGGGGCGGAGAGCGATCCCAACGCGGCCAACCTGGTCCGACACGTTCTCGCCGGCCGCGGCGACGTCCGGGTCACCGACGCGGCCGATACCGGATTATCCGACGCCAGCGCCGATGTCGTCATCGGCGAGGCGATGCTGACCATGCAAGGCAACGCGGCTAAACACACGATCGTCGCCGAGGCGGCGCGGGTGCTGAGGCCGGGTGGCCGCTACGCGATTCACGAACTAGCGCTGGTGCCGGACGACGTCGCAGAGCAGGTCCGCACCGACCTGCGGCAGTCGCTGGCCCGCGCGCTCAAGGTCAATGCGCGTCCGCTGACCGTTGCGGAATGGTCGCACCTCTTAGCGGGCCATGGACTGGTCGTCGAACACGTTGTCACCGCTTCCATGGCGTTGTTACAACCGCGACGGGTGATCGCTGACGAAGGCCTCCTGGGTGCGCTGCGGTTCGCCGGAAACCTGCTCATCCATCGTGCCGCGCGTCGGCGAGTCCTGTTGATGCGCCACACATTCCGCAGGCATCGTGAACGCTTGACAGCCGTCGCCATTGTCGCGCACAAACCGCACGTCGATTCGTGATCCATTGAGGACCTAAGCCCGTTGGGCTAGTGACAAACGCCTCCTGAGCAAAACCCTCCTCCCCCGTTACCGTCGTGCGGTAGGGACAAGCCACATCGGCCGAGCGGGCGATCAGCCAACGACAGGAGGACCGCGATGTCATCGGGCAATTCATCTCTGGGAATTATCGTCGGGATCGACGATTCACCGGCCGCACAGGTTGCGGTGCGGTGGGCAGCTCGGGATGCGGAGTTGCGAAAAATCCCTCTGACGCTCGTGCACGCGGTGTCGCCGGAAGTAGCCACCTGGCTGGAGGTGCCACTGCCGCCGGGCGTGCTGCGATGGCAGCAGGATCACGGGCGCCACCTGATCGACGACGCACTCAAGGTGGTTGAACAGGCTTCGCTGCGCGCTGGTCCCCCCACGGTCCACAGTGAAATCGTTCCGGCGGCAGCCGTTCCCACATTGGTCGACATGTCCAAAGACGCAGTGCTGATGGTCGTGGGTTGTCTCGGAAGTGGGCGGTGGCCGGGCCGGCTGCTCGGTTCGGTCAGTTCCGGCCTGCTCCGCCACGCGCACTGTCCGGTCGTGATCATCCACGACGAAGATTCGGTGATGCCGCATCCCCAGCAAGCGCCGGTGCTAGTTGGCGTTGACGGCTCGTCGGCCTCCGAGCTGGCGACCGCAATCGCATTCGACGAAGCGTCGCGGCGAAACGTGGACCTGGTGGCGCTGCACGCATGGAGCGACGTCGATGTGTCGGAGTGGCCCGGAATCGATTGGCCGGCAACTCAGTCGATGGCCGAGCAGGTGCTGGCCGAGCGGTTGGCGGGTTGGCAGGAGCGGTATCCCAACGTAGCCATAACCCGCGTGGTGGTGCGCGATCAGCCGGCCCGCCAGCTCGTCCAACGCTCCGAGGAAGCCCAGCTGGTCGTGGTCGGCAGCCGGGGCCGCGGCGGCTACGCCGGAATGCTGGTGGGGTCGGTAGGCGAAACCGTTGCTCAGCTGGCGCGGACGCCGGTCATCGTGGCACGCGAGTCGCTGACTTAGGTTCAGCGGCGAACGACAAGCACCGAACACTCGGCGTGACGGAACACCGGATGTCCGGATGGCCCGACCAGCCGCGCTAGCTGACCGGCCTCACCACCGCCGATCACTGCCAGCTGTACGCGCTCGTCGTGGTCGGCCAGGAACCGGGCAATACCCGTGTGAGTGGTGATCGGGTAGACGCGCACATCGGGATGACGGTGGTGCCAATCCTGCACGCGACGTTCGAATTCGCCGTCCGGAATCTCCCGGAGCTCCTCCGGTCGCCCGCCGAGTGCCAGTATGGGCGCTTGCCGCAACTTCGCTTCCCGGGCAGCGTATTCCAGCACGGCCTCGTTATCCGGTGCGTCGGTCATGCGCACCACGATCCAGTTGATGTCAGACGCTGGCTGGTCCACTTTTGAGCGCATGACGGCGACCGGGCAATGCGCCTTTTCGGCCAGCTCGGTTGCCGTCGAACCCAAGATCGAGCTGGCGTAGCGCCCGATTCCCACGGAGCCGACGCAGATCATCTCGGCGTCGCGCGATGCCTCCACAAGCACCGGGCCGGCTGGCCCGCGGGGGATGTCGGTTTCGATCTTGACGAGCTTGCCCGCGGCCTCAACAGCGGACTGCGCTTCCCGAAGCGATCTTTCAGCATGCGCAAGGTCGCGGTCGTAGTCGTCCGGGGACGGATGTGTCGGCTTGATCACTGAGACCAGTCGCAGCGGCACCGCTCGGCTGATGGCCTCGTCAACCCCCCACAATGCGGCCGTAATCGCCGCGTGCGAACCATCGATACCAACAATGATTGTTTTCATCGTCGGCTCTCCTCTCCCAGACATTTCCCGATGCTCGATCACCCCGCATCGGAAAACCTGTCCGCATCTTGGGGACTCGTGGTAAAGGTCGGTTCCGGCTGGGCCAACCGGTAGACGTCAATCAGCCGCGCGACATCGCTGGGAGTGACGATGCCGACCACCGCGCTCCCTTCGGTGACCAGCGCACGGCTGCGCGGGCCGAGCGGTGCCATCCGCTCTAGGAGCGCGGTCAGCGGCTCTTGTGGTCGGGCGGTCGGCACGCTGTGCAGCGGCAGCGCAATGTCACCTACGCTGGTAGTGCTGCGCCGGCTAGGCGCAACATCGCGCAGCTGCCGCAATGCCACCAGGCCCGTGATCGATCCGTCCCGATCGGCAACCGGATATGCCGAGTGCCGTTCACCAAGCACGTAACGCTGGATGAAATCCTCGACATTGATCCATCCGGGAGCCGTATGCGGTTGGGCGGTCATCGCATCGGCCACACGCACCCCGGCAAACAGCTGCTGGGTCGAAATCCGGGTCTCCTCCTCGCGAGCGGCAGCGAAGATAAACCAGCCAATGAAGGCTAACCAGACCCCACCGACGAGGCCACCAGCCACAAACTCGGCCAATCCCAACGCGATCAAGACCAGCGCAACCACCCGTCCGGCCCGCGCCGCACCGATCCCGGCGCGCACACTATCGCCGTGGCGGCGCCACAGATAGGCCCGGACCAACCGCCCACCGTCCAACGGCGCGCCAGGCAGCAGATTGAACAGCCCCAGCAGCAGGTTGACAGTAGCCAACCACCAAGCAACGCTGATCACGATGGCCGGGGTCCGCACGCCGGCGAGCGTGATGGCCAACGCACCGAATGTCGCCGACAGCGCCAGGCTGGTAGCCGGACCCGCGAACGCGATCCGGAAAGCGGCTTTGGGCGTCTTTGCCTCGCCGCCAAGCGCGGTCACCCCGCCGAACAGCCACAACGTCACGCTCTCAACGGATACCCCGGCGCGACGAGCGACGACGGCGTGCGCGAGCTCATGAGCCAACAGCGACGCCAGCAACATGACCGCGCCACCTGCGCCGAGAAGCCAATAGACCACGGCCGGGTAGCCTCCGACGGTACCCGGCAACATGGTCGCCAGACTCCAGGTGAACAACCACAGGATCACCAACACGCTCCAGTGGACGTTCACCACAAACCCGGCGATCCGCCCAAGCGGGATCGCATCACGCATTGGGTACCTCCGATGCTGGCGGATAAAGCCTTTCGTGCCGGCGGATGATCCGAGGTCGCTAGCTGGCGAGGGCCATGGGCGAGCAGATTGCCTTGACGAACTGCACAATGGCGTGCTCGGGCAGGTGTCGGGCGATGTCGGCTTCGGTGACGATTCCGACCAAGCGGTGCTCTGAGATGACCGGAACACGGCGGACCTGATGTTCTTCCATGACGTTGAGCATCTCCTGGATGCTTGCGTTCGCATCGACGTAGTAGATGCTGTCCCGGGCCAACTCGCCAGCCGTGGCGGTATTCGGGTCTAGGCCCGCAGCCAGGCCTTTGATCACAATGTCGCGGTCGGTGAGCATGCCGTGCAGCCGGTCGTCGTCCCCGCAGATCGGCAACGCGCCGATGTCGTGCTCACGCATGTATTGAGCGGCAGCGGTTAGCGTCTCGTGTTCGCCAACACAGGTCACACCTGCGTTCATGATGTCGCGTGCGGTGGTCATCGGGATCCTCCTCGAGTCGGGGTGCTATTGCTGATCTGCTGCCGAAGGTACGACCACGTCGTAGCGAACACTAGGGTCGTTTGACCCGTGGGCCGCGGGTCGATGGACCCGTACTGGCGCGCGTTGAGGCAGCTGGCTTGCCTGGCTTGTCCTCGCCGTAGGCCACCTCAAAGTCGAAGGTTGTCAATTGATTTCACCAGCCGGATATAGCGCTATGGGCGGCCGCAGGACCGATAGTGATGCCGATCGGCCCCGATCGGGGTAACCGGCAATGGAACAACTGACAACCATGAAGGCTCGTTTCGACGGAAGCGGAAGACGCCGACAGGCACATGAGCCTCGCGACGGGGCCAATCCGTTGGCTTTGCGACCGTGGTCGTAGGTCCTGGCGGAGCCGGGTTGCCACATCCGTCACAAGCTGACACGCCGAACGTGCAACCAGGGCGGCATCGCCTGGGTGTGTCTCCGCCACCAGTGCACATTCGGCGCAGCCAGCCCACGCTCGGCGCGGAGTTAGGCGGAACGGTCGCGCTGTGTCCGTGGCGCGTCCAACAGGCCCGACTGCTCCAGCGCAGCCTGGACAAACCGTCGTACCGGCCGCGACTGGAAGAAGCCAGTGTGACCGCCTGGATACCACACGATTTCGGGTTTGCCCCAGTGCTCCCAGAGGCGAGTCACCTGTTCGCGTGGATGCACGAGTCGGTCGGCAATGCCCGCGTAGATAAAGCGGCCCGGCATGGGCACCAGTGGCGTAAGTGAGAGCGGCGAGATCATTCGGCCGATCGGTTCGGCCATCTTGACGGTGTGGCGGCGGGGGTCTTTGTGCCGAAGACCGCAGTGGCGGCCCAACAACTCGATCAGATCAGCCACTGGGACACCGAGAATCGCGCAGGCGAGACCTTCTTCGAGGCTGGCGACCAATGACGCGATGTAGCCGCCCAGCGAGAGACCGTTCAACCCGATCAGCGACTCCTCCTCCTGCGATCGTATCCAGGACAACAGCCGCCGGATATCCCACACCGCTTGAGCCGTCCCATGCACATCGTCGAGAACATCTTCTCCGGGAAAAACGGCGCCCTTCGGCAGACCTTGCCCGCGGGGACCATGCATCGGAAGAACCGGCATGACAATGTTCAGGCCGAGTTCGTCATGCAGCTTCCAGGCGCGGAACACCGCGAGATCCAACGGGGCCCTGCCCATCTCGGTGCCGTGTACACAAACCAGCCAGGGACGCGGCTCTGGGTGCCGCAGTAACAGGGCGTACTCGCGATTGTTCGCAGTGTATGAGAGCCACCGTTGGCTGCCCGGTTCACCCGGATGCGGCGTAAACCCACTGTCGAAGAAGATGCGATAAAAGGAGCGTCTGCGGTCCTTGACCTTTCGGACCGCGACCTCGGTGAGCGGTGGGGGCTGGGCAAAAAATCCGCTAGGCTTCTCCAGCCATCCGCGATTCCCATAGAACTCCAGTCCAGCGGCCACTTCTTGGCTGATGCGCTCGAACACTCGATGATTGCTGACCGGACGTCGTGCCTTGAGGCCCAGCAGGACGATTTCGTCTCGAAAGGCTTGCGCCGCTAAGGCAATAGTGGGCCGTGCGATCGGCAGTTTATCGGGCTGTTGACCCAGATAGTCGCGCCACGATTGAGCGACGTACAGACCGGTGTGCATGAACGGTCCCATGGCGCCGCTCAAGACCGGTGGACTCAGGCGAAAAGCCGAGCGTTCGTGGGTGCCGTCGCTCGCAGAACTTGCCATGGCAGCAAAGCTAACCGCGTGCGGAACGACGCGTTAGGGACTTACGTCCCGCCGGAAGTCACCTGTGTGGTGGTGGCCACTGTCGAGACCGGCGGCCCGTTGTGGTGGCCCAAGTGCCCTAAGGTGATCAGGTGCCGCAGCCCGGCCAGCACGCCGTCAGAGTTTCACGGGGCTTGGTCGCGGCCGATGGCGTCCTCATCGTGGGGTCGATGACCGAGGTGGACGCGGCGCGACCGGGCACATCGACGGTCCCCGGGGCTTTGTGGGCCAGTGAAGTGACGAAAGACCCCAGTGGACACGGACTTCGGCATGTCCACGCAACGACCGAGGCACTCCGGTATTCGGGCTGTTGGCCCCTACGCATGGGCCGGCCGATGTGGTCGGATAGGCAGGTGGGGGGTGCACCAGGAGGCGATGATGAATCTAGCGATATGGCACCCGCGCAAGGTGCAATCCGCCACCATCTATCAGGTGACCGATCGCTCGCACGACGGGCGCACAGCACGGGTGCCTGGTGACGAGATCACTAGCACCGTGTCCGGTTGGTTGTCGGAGTTGGGCACCCAAAGCCCGTTGGCCGATGAGCTTGCGCGTGCGGTGCGGATCGGCGACTGGCCCGCTGCGTACGCAATCGGTGAGCACCTGTCCGTTGAGATTGCCGTTGCGGTCTAAGCACCACCTAACGGTGTCGTCCCGAAGGGACGATTGCCGATCCGGTGGATGACTTTGGTCCCTATGCCTTCCCGCTGGACCGCACAACGATCGAAGGTGCCACGACGCATAGAAGACATGGCCATGCCACACCCTGATAGCATTGCAGCAAGCTACATGTACTGCTCTACCAGGATCCTTATGGGCAACAGTGGGTTTGAGTTATGAAACCCGTGGGCACATACCCTTCCGCGTCGTACTGGTCAGTCTCGACAGCGAAGAGATCACCGGTTGATCCACCAAGCATGCATTGGCGGGCATCTGCATAAACGGTGACGTATCAGCACAAAACAGCGGAGAGAACAACATGCGATCAGAACGTCTCCGGTGGCTGGTAGCCGCAGAAGGTCCGTTCGCCTCGGTGTATTTCGACGACTCGCACGACACTCTTGATGCCGTCGAGCGCCGGGAAGCGACGTGGCGCGATGTCCGGAAGCATCTCGAAAGCCGCGACGCGAAGCAGGAGCTCATCGACAGCCTCGAAGAGGCGGTGCGGGCTTCTCGACCGGCCGTCGGCCAGCGTGGCCGCGCGCTGATCGCGACCGGCGAGCAAGTACTGGTCAACGAGCATCTGATCGGCCCACCACCGGCTACGGTGATTCGGCTGTCGGATTATCCGTACGTCGTGCCATTGATAGACCTTGAGATGCGGCGACCGACGTATGTATTTGCCGCGGTTGATCACACCGGCGCCGACGTCAAGCTGTATCAGGGGGCCACCATCAGTTCCACGAAAATCGATGGGGTCGGCTACCCGGTGCACAAGCCGGTCACCGCCGGCTGGAACGGCTACGGCGACTTCCAGCACACCACCGAAGAAGCCATCCGAATGAACTGCCGCGCGGTCGCCGACCATCTCACCCGACTGGTAGACGCTGCCGACCCCGAGGTGGTGTTCGTGTCCGGCGAGGTGCGGTCACGCACAGACCTGCTTTCCACATTGCCGCAGCGGGTGGCGGTCCGGGTGTCGCAGCTGCATGCCGGACCGCGCAAAAGCGCCTTAGACGAGGAAGAGATCTGGGACCTGACATCCGCGGAGTTCACCCGGCGGCGGTACGCCGAAATCACCAATGTCGCACAACAATTTGAGGCGGAGATCGGACGCGGATCGGGGCTGGCGGCCCAAGGGTTGGCGGAGGTGTGTGCGGCTCTGCGTGACGGCGACGTCGACACGCTGATCGTCGGAGAGCTAGGCGAGGCCACCGTGGTCACCGGTAAAGCGCGTACTACGGTCGCGCGGGATGCCGACATGTTGTCCGAACTCGGCGAACCGGTAGATCGCGTGGCAAGGGCCGATGAGGCGTTGCCATTCGCCGCGATCGCGGTAGGTGCCGCATTGGTCCGTGACGACAACCGGATCGCGCCACTAGATGGGGTGGGCGCATTGCTGCGTTATGCCGCCACCAACCGACTCGGCAGCCATAGATCCTAGGATGCTGCACCGCGACGATCACATCAATCCGCCGCGGCCCCGCGGGTTGGATGTTCCTTGCGCCCGCCTACGAGCGACAAATCCCCTGCGCGCCTTGGCGCGTTGCGTTCAGGCGGGCAAGCCGGGCACCAGTTCAGGGCATCGGTCCGTGCCGCATACGGCGGACTTGCGAATCGAAGCCTGGGCACCGACCCGTGACGGCTGTATCCGGCAGGCGGTGCTGGGTACCGTCGAGAGCTTCCTCGACCTGGAATCCGCGCACGCGGTCCATACCCGGCTGCGCCGGCTGACCGCGGATCGCGACGACGATCTACTGGTCGCGGTGCTCGAGGAGGTCATTTATTTGCTGGACACCGTCGGTGAAACGCCTGTCGATCTCAGGCTGCGCGACGTTGACGGGGGTGTCGACGTCACATTCGCAACGACCGATGCGAGTACGCTAGTTCAGGTGGGTGCCGTGCCGAAGGCGGTGTCACTCAACGAACTTCGGTTCTCGCAGGGTCGCCACGGCTGGCGATGTGCGGTAACGCTCGATGTGTGAATTGAGACCTGATTCATGAAAATCGTCGAGGAGACCCCATACCGGTTCCGGATCGAACAAGAGGGCGCGATGCGGGTGCCCGGGATCGTGTTCGCGTCCAGGTCGTTGCTGCCTCGTGACGAAGGCGACATGGCCCTTGATGCAAGTGGTCAACGTGGCTACGCTGCCGGGGATTGTCCGGGCCTCGTATGCGATGCCCGATGTGCACTGGGGATATGGTTTCCCAATCGGCGGCGTGGCCGCAACCGACGTCGACAATGATGGAGTCGTTTCCCCAGGCGGTGTCGGCTTCGATATTTCGTGCGGCGTAAGACTCTTGGTCGGCGAAGGGCTGGACCGCGAGGAGCTGCAACCACGGTTGCCGGCGGTCATGGACCGGCTTGATCGCGCGATACCGCGCGGAGTGGGCACGGCGGGTGTGTGGCGACTACCCGACCGGAACACGCTGCAGGAGGTGCTCACCGGTGGTGCCCGGTTTGCGGTGGAACAGGGGCATGGCGTCGCGCTAGACCTCGAGCGGTGCGAAGACGGCGGTGTGATGACAGGAGCGGACGCGGCCAAAATCAGTGACCGGGCCCTCCAACGCGGGCTTGGGCAGATCGGCAGCCTTGGCTCGGGCAACCACTTCCTGGAAGTCCAGGCCGTGGACCGCGTCTACGATCCGGTTGCGGCCGCGCCGATGGGTCTGGCGGAAGGGACCGTCTGCGTGATGATCCACACCGGCTCACGGGGCCTGGGCCATCAGATCTGCACGGATCACGTCCGCCAGATGGAACAAGCCATGGGCCGATACGGAATCGCGGTGCCCGATCGCCAATTGGCTTGTGTGCCGGTGCACTCCCCCGATGGGCAGGCCTATCTCGCCGCGATGGCGGCGGCGGCCAACTACGGACGCGCCAACCGCCAACTGCTGACCGAGGCGACGCGTCGTGTGTTCGCTGATGCAACCGGAACACCTCTGGACCTGCTCTACGACGTGTCGCACAACCTGGCCAAGATCGAGACGCATCCGATCGACGGTCAGCTGCGCTCGGTGTGCGTGCACCGCAAGGGCGCCACCCGCTCGCTGCCGCCGCACCATCACGAGCTGCCGGCCGAACTGGCAGCGGTCGGCCAACCCGTGCTGATACCCGGGACGATGGGTACGGCGTCATATGTGCTTGCCGGGGTCACCGGCAACCCGGCGTTCTTTTCCACCGCGCATGGTGCTGGGCGGGTACTGAGCCGTCACCAGGCCGCCCGCCACACCAGCGGTGAAGCGATACGCGCCAGCCTCGCAAAACGTGGCATCATCGTCCGCGGTACCTCTCGTAGGGGTATCGCCGAGGAAAAGCCGGAGGCCTACAAAGACGTCGACGAGGTCATCGAAGCCAGCCATCAGAGTGGCCTCGCGCGCAAAGTGGCTCGCCTTGTTCCCTTGGGCTGTGTCAAAGGATGAATCAACGGCGAACATTCCAGCCGTCGCGACCGCCTTCTTCAGTGGTGCAGACCCGTGACCGGCTGATGGGTACTGGCTTCGATATCCGACGACGTCAAAGCGAATAGCTGATTCGCCAAATCCGACAAGGCCCGGGCGATCGCAAGTTCGTCGCCGATCTGGGCCACCGGCTCATCGGCCGGATCGAGTCGCGCCAAACCAACACCCACCATCTGCCTGCCTGCCCAGGACAGCCGCGCCTTCGCCCGGGTGCGCTCGTCGTGTTCCTCAATCAGCACATCAATTTGGCAGGTTTTTCCAACGTGCTCGCTGTCTGTCATCGCGGCCTCCCTGTCGGATTTGCGCTTACGCCCGCCGATCTGCCCCGCTAGCTGAACGCGGTATCTATCCAATCACCACAATCGGTCGTGGAGTAGGCCAGAATTCTTTTCGCCCGACCCGGGCCCGCCTAGCACTGACAACCGCTAGATGGCCTTCAGGAGGTCTGCTTTGCCCTTGGTACGGAGTGTGTACAGAGGTGAGCCGCGCAACTGCTCAATGCGAGCCGCCATCTTGTCACCGAGCTCCTCGAGCTCGGCATCGGTGATGTGCACCGGTGTAGGAGCGGGGATCATGTCGCGTTCCTCTACGTCGGCGTGCGCCTCCAACACGGTCCGGAACACGTTCCACTCTTCTTCATACCCGGGCGCGCGCTGCGGAGTGCGCAGCAGCGTCGCGAGCTGATCAACCACCTGACGGTGCTCGGCGTGGGTACCCGTGATTGGTTTGCCGGCCGCGGAAAGGGCAGGGTAGTACAGGTCATCCTCGATGCGGAAGTGAATGTCCAGCTCGATGAGCATCTCGTCGAAAAGGACATGGCGCTCTTCGCTATTCACCGGCGCCTCGCCGACTTTGCGGCCCAGTCCTTTAAGCACGGTGTGGTGGCGCTTTAATACGTCGTAGGCATTCACTTCGTTGCTCTATTCCGTATTCGGGATCAACGAGACAACCGTAACCTCGCGCCGCGGCCCATTAATGTGAGGTAGCTGTGAATCAGCACAAAGAAGCCTGTGCAGTAGCGCGACGCTCGGCGTACCGGCACGAGTCCGACGGCCCGCATGTCCATGCGGCCGCCGGCACCAGCGCCGAGGCCCCCGCAGGATACCGGGATCTGCAGCTCCTCGTGCGGAAACAGTTGCCGCAGTTCGGGTTCGGGCAGTTCGGCGAGCGTGATGTTCGCGCCTAACGGCAACAACTATCCGTCGGCGCCCTGGGTGCCGGGCGGGCCCATATTGCCCTGGATGCCGGAGCTGCCACCCGGTGACCCACCCGCGCCGCCGGCGCCCCCGTTGCCGCCCAGCGCGAAATCGCCGCCCTGACCGCCGGTCGCGCCGGTCCCGCCGTTGCCGCCGTTGCCGCCCTGGCCGCCGAGGCCACCTTGCCCACCCGTGCCGCCTGCGCCGGTGCCGCCGGCAGCTCCTGCCCACCCGATCAGCCCGCCGGCTCCGCCGCTGCCGCCGGTGGTCCCGCCGGCGCCGCCGGTACCGCCAGTGCCACCAGCGCCCCCCACGCCGCCTGTACCGCCGCCACCGCCAATTGTCGCTCCCCCGCCGGTGGTGGTACCCGCGCCGCCGGCGCCACCGTTGCCGCCGGCACCACCGATGCCGCCGATGCCACCGGTGCCGCCGACACCGCCGGCACCCCCGCCACCACCAAGCCCGATGAGCGACCCAGCCGCCCCGCCGTTGCCGCCGACACCGCCGCTGCCACCCATACCGCCGGTACCGCCGACACCGCCGAGGCCCCCCAGACCGCCGGTGCCGCCTTCCGCGGTACCCGCACCGTCGGTGAGACCCTCTCCGCCCGCGCCGCCGACACCGCCCGCGAAGCCGGCGGCGCCACCACCACCGGTGCCGCCCGTCCCGCCGGCCCCACCGGCGCCGCCGTTGCCGATTAACATCCCGCCACGTCCACCGTTTCCACCGGCACCACCGGTGCCGCCGTTACCGCCCGCCGCGCCTAGTGCCCCGTTACCGTCACCGCCGATTCCGCCGTCACCGCCGAAAGCGTCACCTACACCCGTGTTGTGCCCCTGCCCCCCCCTTGCCGCCAGCACCACCCACGCCACCGTCGACCCCTCCGGTGGCACCGTCACCCCCCTCACCCCCGGTAGCCACGCCGCCGGCGCTGCCGTCGGTCTCACCTATGCCGCCAGCGCCGCCAGCGCCGCCGGCACCGCCATCGGTACCGGCAGTACCCCCGGCTCCACCCTTACCGCCGGTGCCGTCGTTGCCGTCGAGCGACTCCCCCAGCCCGCCCTGCCCGCCGACGCCGCCAGCCTCGCCGACGCCACCGGCGGGGCCGGGACCCCCGTTCCCGCCAGTTTGATTCCCGTTGCCGCTGTTGTCGGTACCGTTCGCACCGGTGTTGGGGTTCGCAATCGAGCCGGGGTTGACCCCGTTTGTCCCGGCCAGACCGGTGCCACCCTGCCCGCCGGCACCACCGGACCCGAACCAGTTGGCATTACCGCCGTTGCCGCCCGCGCCGGGCATCCCGCCCAGGACACCCGCCACGGCCGGCCCACCCTGTCCGCCGGCACCGCCATCGCCCAACAACATCCCGCCGGCACCGCCATTACCACCGGCCGCCCCGGCCCCACCCAGACCCCCAACACCGCCATTGCCGATCAATAGCGGACCCGCACCGCCGTCACCACCGGGCGCACCGTCCCCACCAACGCCGCCACCGCCCCCGGTCCCGAAGTAGCTGGCCGCCCCTCCGACGCCGCCGGCGGCGCCAAGGCCACCGGCCCCGCCGAATCCACCATTGCCGAACACGCCGCCAACGCCACCGCTCCCGCCCACGCCGCCGGTGGTGCCCACCCCCGCCGCGGCCCCGCCAGCACCGCCGAAGCCCCCGCTGCCGATCAACCCCGTCGCCCCACCGACACCGCCAGTACTGCCGACCAAAGTGGCCCCTGCAGCCCCACCAGCCCCACCGGTCCCGCCATTACCCAGCAACCATCCACCGCGACCACCGACACCCCCGGCAGCACCGGACCCGACCAGCCCGTCCCCACCTTTACCGCCAGTCCCGCCGTTACCGATCAACCCCGCATCCCCGCCAGCACCACCTGGCTGACCCGGCGCACCCGATCCGCCATTCCCGCCGTTGCCAAGCAACAGCCCGCCCGGCCCACCGGGAGCCCCCGTCCCGTCGGCCCCGTTAGCGCCATTGCCGATCAACGGGCGCCCCAACAACGCCTGGGCGGGGGCATTTACCACGCCCAACAAATCCTGCAACGGCGCAGCACTGGTGGCCTCGGCAACTACGTATGAGCGCGCGCCGTTCGTAAGGGACTGCACGAACTGGGCGTGAAACGCCGACAGCTGCGCACCAAAAGCCTGATAGCTCTGCGCGTACGACCCGAACAAGGCCGCAACTGCCGCCGAAACCTCATCCGCGGCAGCCGCCACCACCCCCGTGGTCGGCAATGCCGCCGCCGCATTCGCCGCGTTGATCGTCGACCCAATGTTGGCCAGATCCGAAGCCGCCATCGTCAATGCTTCCGGCACCGCAATCACAAATGACATCTGCGACCTCCTGGACCGGACAACCCGCATGGTCGCCGCGGATCATCGAGCACTCGGCAGCAACAAATCCTATCCCGCCTCGCAGACGGCGGAGGCCATTTGGCCGCCGGCGCGTACTCTTCGCTACGACCGCCAGAGCCCTTGGTTAGCGACCGGATTCGACCGCCGCATGAGCCAAACTGTTACCGGTGTGGGTGTGCAGAACTGCGCAGTTAGCAAACGCCGATGCAGCGCGGTGGACCACAGCAGCCGCACACCGTACCGGCGCTGAGTGATAAACCCGACCCGGGCCCGGCGGATGCGATATCGTCTTGCGGCTATGGCGGGTATGCCAGAGGGCAAACTCATCCTCCTCAACGGCGGATCCAGCGCGGGAAAGACGTCGCTCGCCTTGGCGTTTCAGGATCTTGCCGCCGAGTGTTGGATGCACATTGGGATAGATCTGTTCTGGTTTGCGCTGCCGCCAGAGCAGCTTGACCTTGCGCGGGTGCGGCCCGAGTACTACACATGGGACAGCGCGGTCGAGGCCGACGGGCTGGAGTGGTTCACCGTGCACCCGGGCCCCATCTTGGACCTGGCCATGCATTCCCGCTACCGCGCCATCAGGGCATACCTGGACAACGGAATGAACGTCATCGCCGACGACGTGATCTGGACACGTGAGTGGCTGGTAGACGCTCTGCGGGTTTTTGAGGGCTGCCGAGTCTGGATGGTCGGGGTCCACGTATCCGACGAGGAGGGTGCCCGCCGGGAATTAGAACGCGGCGATCGCCACCCCGGGTGGAACCGAGGCAGTGCGCGCGCTGCCCACGCCGACGCCGAGTACGACTTCGAGCTGGATACCACCGCGACCCCGGTCCACGAGCTGGCCAGGGAGCTGCATGAGAGCTATCAAGCCTGCCCGTACCCCATGGCTTTCAACCGGTTACGCAAACGCTTCCTATCTTGAAATGGAGCCAAAAGTCGTGCGCAACTGGAACTTTCACTCCTGGCAAACGCTGGGGCGACCCGTCACCGCGCGCTTGGGTTCGGGTCGAATCGTCGGCCGCGCGGGTCGTGCGGAACATTGCACCCGACGCGGCGGAATCGGAGTTGAGAAGTACATGGCGGGACGCACCCGGCACCGGTCAGGCATTCTTTACCCATGGATGTGGAGGCCCTGCTGCAGTCGATCCCGCCGCTCATGGTCTACCTGGTGGTCGGCGCGGTGGTAGGGATCGAGAGCCTGGGCATCCCCCTTCCCGGCGAGATCGTGCTGGTCAGTGCCGCGGTGTTGTCGTCGCACCCCGAGCTGGCCGTCAACCCGATCGGCGTCGGCGGCGCTGCGGTGATCGGCGCCGTGGTCGGCGATTCGATCGGCTACTCGATCGGCCGCCGCTTCGGCTTACCGCTATTCGACCGGCTGGGCCGGAGGTTCCCAAAACACTTCGGCCCCGGTCATGTCGCGCTTGCTGAACGGTTGTTCAACCGATGGGGAGTCCGAGCCGTGTTCCTCGGTCGCTTCATCGCGCTGCTGCGGATATTCGCCGGACCGCTCGCTGGCGCCCTGAAGATGCCCTACCCGCGCTTCCTGGCCGCCAACGTCACAGGCGGCATCTGCTGGGCCGGCGGCACCACTGCACTGGTCTACTTCGCCGGGATGGCCGCCCAGCACTGGTTGGAACGGTTCTCCTGGATCGCGCTGGTCATCGCGGTCATCGCCGGCATTACGGCCGCGATCTTGCTGCGCGAACGCACTTCGCGCGCGATCGCCGAACTCGAGGCCGAGCACTGCCGCAAAGCCGGTACCACCGCGGCGTGACCGACCGGCTTGAATCCGGTACCCACGCTCACAGGAGCTGCAATCTAGACAGATCTCCAGTCATGTCATAAAAATGAGATCTGAAATTACTTGACAAGCTTGTCTTCGGACAGTGCGGGGCATCCGCCGCGGTGGCTGTACGCCGTCGATTAGGAGCGCACCATGGGCCTGATCACTACAGAACCACGCTCTAGTCCCCACCCGCTCAGCCCACGGCTCGTCCACGAGCTAGGCGACCCACACAGCACGCTGCGGGCAACCACTGACGGCAGCGGGGCAGCGTTGTTGATCCACGCGGGCGGCGAGATCGATGGCCGCAACGAGCATCTCTGGCGTCAATTGGTCACCGAGGCCGCCGCCGGCGTCACGGCGCCCGGACCGCTCATCGTCGACGTCACCGGGCTCGATTTCATGGGCTGCTGCGCTTTCGCCGCACTGGCCGACGAGGCACAACGATGTCGGTGCCGCGGCATCGACCTGCGTCTGGTGAGCCACCAGCCGATCGTCGCCCGGATCGCCGAAGCGGGTGGGCTGAGCCGAGTGCTGCCCATCTACCCGACCGTCGATACTGCGCTCGGCAAGGGCACGGCCGGTCCAGCCCGTTGCTGATCCCGGCCGTAAGAGCACCGAGCCGACCGCCGGTGGCCCCACCGCTAGGGCCGATCGCACCGCCGCGCGACGATGTTCGCGTCAGGCGCGCATGCGGTATCGCTTGCCTTGCAAGGTAATCCACTTCGGACATCCACGATGCAGGTCGCGATCAAGTCGGGCGCGCCGCAGCAGTCAGTGGCCGCGAGGGGCGTACATGATCACGGCTACCCCGGCCATGCAGCCAAGGGCACCGATGACATCCCACCGGTCGGGCCGGAACCCGTCCAGGGCCATGCCCCAGGCGAGCGAACCGGCGACAAACACACCACCGTAGGCGGCCAAGACCCGACCGAAATGGGCGTCCGGCTGCAATGTGGCGAAGAACCCATAGACCCCAAGCGCAATAACTCCGAGTCCCGCCCAAAGCCAACCCCGTTGCTCGCGGACGCCCTGCCATACCAGCCACGCGCCACCGATCTCCGCAACCGCCGCCAGGACGAATAGCAGGATTGACCGCACCACCATGGTTGCGAGCCTACGAGATCCGCTGCCCTGCCGCCCCCCAACCAATCGCGCACCCCAAATGCTTCCCGTCACCCGCGCTCAGCCAGACACCGGTGTTGGCTACAACTATGGTTCCCGGATCAGGCGCAGCAGTTCGGGTTGAGCACGGTACACAGCGCTTGCAGGGCTTCAGGATGTACCCGATGGAAGACGTGCATGCCCCGGCGATCGGAAATGACCAGGCCGGCCTTGCGCAGCTGGGCCAAGTGGTGGCTGACGGTGCCATCGCTGAGGCTGAGCGCCGCCGCTAGTTGGCCGCTGACCTGCTCGCCGGCCGGCGAGCTGAACAGGTAGGACATGATCTTGACTCGTGCCGGGTCGGCCAGGGCCTTCAGCCGCAGCGCCACCGCCAAGGCGTCGCCGTCGCTCATCGGCCCCGCCGCCACCGGGGCGCAGCACACGGGAGCGGAGATGTCAATCACCGGCAGCGACTTGGGCATAGGCCCACCCTGCCAGATACCTTGACATATATCAAAGAGATGTTGCACACTGGGTTCGGCGCCATTTTGATATAAGTCAAACAACTGGGAGGTGTCTACCAATGTCCCGCGTTCAGCTAGCCCTCAACGTCGACGACCTGGAGGCCGCAATCACGTTCTACTCCAGGCTGTTCAACGCCGAGCCCGCCAAACGCAAGCCCGGATACGCCAACTTCGCGATCGCCGATCCGCCGCTTAAGTTGGTGCTGCTGGAGAACCCCGGCACCGGCGGTACCCTCAACCATCTCGGTGTGGAAGTCGGCTCGAGCAACACCGTGCATGCCGAAATCGCCCGGTTGACCGAAGCCGGACTGGTCACCGAGAAGGAGATCGGCACCACGTGTTGCTTTGCCACCCAGGACAAGGTGTGGGTGACCGGCCCGGGTGGGGAACGCTGGGAGGTTTATACCGTGCTGGCCGACTCCGAGACCTTCGGCAGCGGTCCTCGGCACAACGACACCAGCGACGGCGAAGCAAGCATGTGCTGCGACGGCCAAGTCGCCGTTGGCGCAAGCGGCTAACTGTAGGCCTGACCCCGGGGTGCGTCTCCAAGCCGCGGAGCCCACCCCGGGCCACTCAATGCCCCCTAACCCGCGTAGCGCCGTTCACCGCGTGGCCGCTTGCGGACCTGATTCGATATTTGTCAATATTGATGTATGTCGAATCTGCATCCGTTACCAGAGGTGGCGAGCTGCGTAGTCGCGCCGCTGGTGCGCGAACCGCTGAATCCTCCGGCCGCGGCCGAAATGGCGGCCCGGTTCAAAGCCCTGGCCGATCCGGTGCGATTGCAGCTGCTGAGCTCGGTTGCCAGTCGCGCCGGCGGCGAGGCCTGCGTCTGCGACATTTCCGCGGGAGTCGAGGTGAGCCAGCCCACGATTTCGCATCATCTCAAGGTGCTGCGCGACGCGGGTTTGCTGACCTCGCGGCGTCGGGCCTCGTGGGTGTACTACGCCGTGGTCCCCGAGGCGCTGACCGTGTTGTCGAACCTGCTCAGCGTGCATGCCGATGCCGCACCCGCCCTGGGGGCACCGGCATGACGGAGACGGTCACCCGCACCGCCGCCCCGGCGGTGGTGGGCAAACTCTCGACGCTGGACCGCTTCTTGCCGGTGTGGATCGGGTCGGCAATGGCCGCCGGGCTACTACTGGGCCGGTGGATTCCCGGCCTGCACACCGCCCTAGAAGGGGTTCAGCTCGACGGGATTTCGCTGCCGATCGCGCTAGGCCTGCTGATCATGATGTATCCGGTGCTGGCCAAGGTGCGCTACGACCGCCTCGACACCGTCACCGGTGACCGCAAGCTGCTACTCAGCTCGCTGCTGCTGAACTGGGTACTGGGCCCGGCGTTGATGTTCGCGCTGGCTTGGCTGCTACTGGCGGATCTGCCCGAGTACCGCACCGGGCTGATCATCGTGGGCCTGGCTCGCTGCATCGCCATGGTGATCATCTGGAACGACCTGGCCTGCGGGGATCGCGAAGCCGCCGCCGTGCTCGTCGCGTTGAACTCGATCTTTCAGGTGGCCATGTTCGCCGCGCTCGGCTGGTTCTACCTGTCGGTGCTACCGGGTTGGCTGGGCCTCGAGCAGACCACCATCGCCACATCCCCGTGGCAGATCGCCAAGTCGGTGCTGATCTTCCTCGGCATCCCGCTGCTGGCCGGCTACCTGTCGCGGCGGATCGGCGAAAAGACCAAGGGCCGCAACTGGTATGAATCCCGCTTCCTGCCCAAGGTGGGACCGTGGGCGCTCTACGGTTTGCTGTTCACCATCGTGATTCTCTTTGCGCTGCAAGGAGATCAGATCACCGGCCGACCGCTGGACGTCGCACGCATTGCGCTGCCGCTGCTGGCCTACTTCGCCATCATGTGGGTAGGCGGCTACCTACTGGGGGCGGCGCTGCGGCTAGGGTATCGGCGCACCACCACGCTGGCGTTCACCGCCGCGAGCAACAACTTCGAGCTGGCCATCGCGGTGGCCATCGCCACCTACGGCGCCACCTCCGGGCAAGCCCTGGCCGGAGTCGTCGGGCCCCTGATCGAGGTACCCGTCCTGGTGGGGTTGGTCTATGTGTCCCTGGCGCTGCGCAACCGCCTCGCCGGTCCCAACGCGACCCACGATGCCGACAAACCCAGCGTCCTATTCGTCTGTGTGCACAACGCCGGACGTTCCCAGATGGCCGCCGGGCTATTGACCCACTTGGCCGGTGACCGCATCGAAGTCCGTTCGGCCGGAACCGAGCCCGCCGGTCAGGTCAATCCGACGGCTGTGGCCGCGATGGCCGAAATGGGCATCGATATCACCGCCAATGCCCCCACATTGCTCACCGGCGGGCAGGTCCAGTCCAGCGACGTCGTCATCACGATGGGCTGCGGCGATGCCTGCCCTTACTTCCCGGGTGTCTCCTACCGCAACTGGAAACTACCCGATCCCGCCGGCCAGCCCCTCGACGTTGTGCGCATGATCCGCGACGACATCGCAGACCGCGTCCAAGCCCTGATCGCCGAGCTGCTGGCCACCGCCAAGACCAGATAGCGTGTGCCACGCTCGGTGCTGCGCCGATACGTGAGGTCCCGGCTGGGATCGGATTTTCCGCGTGTACGGCGGCTAGGCACCAGCGGATCGCATTTGTACTGGTTAGAGACTTGCCGAGTGGCCGCATTAGCCTGCGTGGAGCGCTTGGTCAAAAAGCTCGGCCCTGTTCGGCCCTATGGGTTCCTGTTGATCTGCCCTGTTCGTAGTCTCGACAAAGCGGCTGCCCGAGATCGCGTGCGACGATATCGGGAGCGGCTGCGGCAACGAGGTCTGCGGCCGATACAGATCTGGGTTCCCGATGTGAACGCACCCGAATTTGTCGGCGAAGCACACCGTCCGTCGGCGCTCGTCGCGGCCCGCGAATACGAGGACGACGATCAAGCCTTCGTCGATGCGGTATCGGTCGACTGGGACGACGCCACCTGACGTGCGGCGCGGCGACATCCACACCGCGGCGGCGCGTGGTGCCTACACCGGCAAGCCACGCCGGTCGCGGTCATCCAGAATGACCGGTTCGATTCGACGGCCTCGGTTACCGTCGTGCCGTTTACCACGCGTGATGTCCAGGCATCCCTGATGCGAATCCCGGCCCCAGCGTCCAACACCACCGGGCTGACCGAGACCAGTCGCCTGACGGTCGACAAGGTGACAACATCCCCCGCACCAGCCTGACGCGGCAGGTTGGTCGGTTATCGGCCAAAAACATGGTCAGGCTCGACCGTGCATTGCTGGTTTTCCTGGCCGGCTGACAATTGCGCCACCTGGTCATCAGAACTGATCGGGCGGGGAAGCGAAACGGGGCTCCCAGCGGAGGTCATGAGTTGGCGCGCCGGTTTCGCCGCGATCTCTCCGAACTTGACCGCTAAACCTCGGGGCAGAAGTCATGAACAAGCCCGTTAGGAGGCGTTTGAGGCCGTAAATGTTGATGAGGGCGGGGAAAGTGTCGTCATGGCCGTCGCGCTGAATTCACCACGCCCCCACGACGGAGCTCGTGGGCACCCAGCATTCACTGCTTACCACTACGATCTCGCTCACGAGGTTCGAGCAGCCACTGTCGCCTGCCGCCAACGAATAATGCTCCCTGACCTAGTGGTCCCGGCTGGGATCGAACCAGCGACCTTCCGCGTGTGAAGCGGACGCTCTCCCACTGAGCCACGGGACCGGCGCCGAGGAGATGAACGAGGTCGAAGATTAGCACGTGCAAGACATCGTCAGCAGCAGTCTACGTGCGCTTCACATAGGGGCTGCGATAGCCTAGAGCCGCAACGTACCAAGAGATTTGTGTGGGCCCGCTCACCTCGACTATCGTCGTGCTTCGCACCGGGCGACGATCTCGTTCGTTGCGCGCGGATGTAGCGCAGTTGGTAGCGCATCACCTTGCCAAGGTGAGGGTCGCGGGTTCGAATCCCGTCATCCGCTCGAAGGTGCTAGTGGCATCAAATCCCAGCGGTGGAGTGGCCGAGTGGTGAGGCAACGGCCTGCAAAGCCGTGCACACGGGTTCGATTCCCGTCTCCACCTCCAGGTTCAACCCCCAGCGCGATTAGCTCAGCGGGAGAGCGCTTCCCTGACACGGAAGAGGTCACTGGTTCAATCCCAGTATCGCGCACCAGTGTTCGAGCAGGTCAGGCCTGGTTTTTACCGGGCCTTCGCCGTTTCCGCGCAATAAACGCGCAATAGTGCCGCCGCTGGGTGCGCCCCACGGAGGAGTTTGCTAAATGACCACCACGCCCCGACAACCCCTGTTCTGCGCCCACGCCGACACCAACGGCGACCCGGGCCGCTGCGCCTGCGGCCAGCAGCTCGCCGACGTCGGCCCGGCCACCCCGCCACCGCCCTGGTGCGAACCGGGCACCGAACCCATCTGGGAGCAGCTCACCGAACGATACGGCGGCGTCACAATCTGCCAGTGGACACGATATTTTCCGGCCGGCGACCCGGTGGCTGCCGACGTGTGGATCGCCGCCGACGATCGTGTCGTTGACGGCCGGGTGCTGCGCACCCAACCGGCGATTCACTACACGGAACCGCCCGTGTTGGGGATCGGCCCGGCGGCGGCCCGCCGGCTGGCCGCTGAGCTGCTCAACGCCGCCGACACCCTCGACGACGGCCGCCGGCAGCTAGACGACCTCGGCGAACACCGGCGGTGAACACCGCGACCCGGGTCCGGCTGGCCCGCAAACGCGCCGACCGGCTCAATCTGAAACTAATCAAGAACGGCCACCACTTCAGGTTGCGTGACGCCGACGAGATCACGCTGGCGGTCGGGCACCTAGGGGTGGTGGAAGCCTTCCTGGCGGCGGCCAAGTCGCAAAACAAGCCGCCCGGTCCGCCGCCGAGCCTCCACGCCCCGCCATCCTGGCGGCGCGACATCGACGACTACCTGCTCAACCTGAACGCCGCCGGTCAACGCCCAGCGACGATCCGGCTACGCAAGACGGTGCTGTGCGCAGCCGCCCACGGCCTCGGCCGCCCACCCGCCGACGTCACCGCCGAACACCTCCTGGACTGGCTAGGCAAACAGCAGCACCTCTCCCCAGAGGGCCGCAAAACCTATCGCAGCACGTTGCGGGGCTTCTTCGTGTGGGCCTACGAAATGGACCGGGTGCGCGACTATGTCGCAGACTCCCTGCCTAAGGTGCGCTGCCCGAAACAGCCGCCCCGCCCGGCCGGCGACGACGTCTGGCAAGCGGCGCTGGCCAAGGCCGACCGTCGAATCGAGCTGATGATCCGCCTAGCCGGTGAGGCCGGGCTGCGACGCGCCGAAGCCGCCCAGGCGCACACCGGCGACTTGATGGACGGCGGGCTTCTCCTCGTTCACGGCAAAGGTGGTAAACGCCGTATTGTGCCGATCAGCGACTACTTGGCCGCGCTCATCCGCGACACCCCGCACGGCTACCTGTTCCCCAACGGCACCGGCGGCCACCTCACCGCCGAACACGTGGGAAAACTCGTCTCCCGGGCATTACCCGGTGACGCGACCATGCACACCCTGCGGCACCGATACGCCACCCGCGCCTACCGCGGCTCCCACAACTTGCGAGCTGTACAACAACTTCTCGGTCACGCCTCGATCGTGACAACAGAACGCTACACAGCGCTGTGCGACGACGAGGTGCGCGCCGCAGCAGCAGCCGCATGGTGAGTCGCCCTGGCGTTTGCTGCAGCCGATCGGCGTCACCCCCGACAGGCGGCTCGTATTCGGCCAGCGGCGGCTCGAGGCTGCACGGCTGCTCGGATGGGAGCGCATCCCGGTGCACGTGTGCCACACGATCGCCGACGTGGTCGACCGGGCCAAAGCCGAACGCTCCGAAAACACGCTTCGCAAGGATTTCACCCCCTCGGAGCTGCTCGCCGCTGGTCGCCGGATCGCCGAGCTGGAACGGCCGAAAGCCAAACAGCGGCAACGCGAAGGCGGCGACCATGGCCGCCAGGCTCGATATTCTGGCTTAGGCTCCATGGAGCCTAAGCCAGAATCAGAGCGCGATGCCCACAAAGCCGACACTGCCATCAGCGAAGCCCTCGGCATCTCCCGCGGCCACTACCAGCGGCTCAAACGAATCGACAACGCAACCCGCAGCGAAGCTGGCTACCGGGATGGTTTAAACGGTTGGAGCGGCTGACCGCCGGTGCCCGGGATGGGCCCCGGCGGCAACTTGTCCAACGGGCGACGCTCACGTCCACGCTTGCGCAGCTCATCTTCGGCGGCCTTGCGTGCCTGCTCAGCCTGGCGGCGCCAAGCCTCATAGCGACGCCGAATCTCCCTCTCAATCGCGCGCTGCACACCCATCCGGAACTGATCCTGGACACGCTGCTGCTGCCGAACCCAACGCTCAAGCTCACGCCGGTAGTCGTTGACTGATCTCGCCACCCAAAATCACCCCTCTTGACCCTCTTGGTTCTCTTTTTGGCGGCGTGGGCGACCCGGCACCCCTAAGTCTCCGGGCCGTGCGGGCCGCTGGGAGCCGAAAGGTTGCTAAAGTTCTCCCTTTTTGCCCGCACGACCCGAAAAGGGCCGCCCACGCCTGGCACCTACGCGGTGGTCTGCACCTTCAGCACGCGGAACGCATTGTCCACCAGCACATCAGAACCGACTCGGAACCAGCAGAAGAATCCGCGCTGTCCGGTCGGTCGGCGGTTGCCGCCGAACACGTGCGGCACCAGCTCCACCGTCGACCCGACCCGGTCGGTGATGATGAACTGCTTCCAGTCGCCAAGCACCAGCGGGTAATTGGTGGCGGTCACCGCCGCGTCCACGGTGTCCATGTTCGACACCTCCCAGATGTGTTTCCCGGCCAGCATCGGCGGGCTGGCGTGCAGCGATGGGAATTTCAGCGCCCCATTCGCGGTTTCCGCCTGGCGCAGCACGTTGATGGTGGACAAGTTCGCCGCGAACGCGCTGTTGGATTGAAAGCGCGGCGGCAACGCCGACTGCAGCGCGTAAACGTCGGCGGCTACAACGGCTTCCGTCCCCGCGCCGGTGACGGTGTAGTCCGCGGTGCCGGTCAGTGCGGAGACGAATCCGGTGGGCTCGCCGTTGCCGGAGCCGCTGACGAACGCCGCCGCCTGCAGCTGCTCAACCGAATCCGCTAGGACGCGGCCCACCTCTGCGACGAATCCGGCGGCGTCACCCTCAATCTCGAGACTGAACGGAATCCAGCAGGAGCCACGGTAGCTCGGCACCGCCGGCTGGGCCAGCGTTGGCGAATCGTCGGACACCTCCTGGGCTTCGGAGTACCAATGAGCCTCGGCGCCTTCGGAGGTCACGCCCCGCCAAACCTCGGAGGTCGTTTGCACCACCCTCGCCACCTGCCGGATCGGATTCGTTGAACCATCACCCGACAGCAGAATCGCCGGATCCAGCGCCGCCGGGATCAAAAACCCGCCGGCGGTGTCCACCAAGCCCATTGCTCGCTGCTCGGCGGCCACCGCGGCCGCCTCACGCCACGCGGCCGCTTCCCGGTCGGTCCAGGTCGTGTGCCCCGCAACAGGGTTCGAAACCCTCTTGACGAACGCCCCCAGGTAGTCGCGGTTGCCGGTGGCCGCCAGCCAGCGCTGCGCCCACGACGTCGACTGCGGCGGCCCGGTGCGGCACAAGGTTTCCGCGGCTTCCGCCGCCCGCGACGACATCAGGCCATCGCGCACACAAACGTCCAGTGTGCGAAACGCGGTGTCGCGCAACGAGTTGCCCGGCGGCGCGTCGCCGTCGTCGCCGCCGGTGGGAGCACCGGGCACCACCCTCAGCTCACCGGCCCGGCAGCGGCGCAGCGCCTCCTCGGCTTCGCGGCCGCGGCGGCGCTGCTCCGCCCGCAGTTCCTCGGCGTGGCGTGTCAGCGCCTGAAAACGTTGCGCCACATCACCGGTCAGGTCGCCCTCGACGGAGTCGAGGAGCTGTTTTGCCGCGGAACGGGTTTCGTCGAGGCTGAGCTGTTTGATGTCGCCATCGTCAGCGAAATGTTGTTCAGTAGTCATGAGAGAGTTACCAATCCATCAGGGCTAACCTGGCTTCGGCTAGCGAACGGGAAACGACTGCAAGCGATTCCGCGCGCACACCGGCGATCTGCGCGCCCAGATAGGCCGGAACGCCGGTCAAGGAGACCTCCAACAGCGCCGCCTCGACCCGCACGATCACATCCCCTTCCCGGCGGTCCCGGATCGGCCGGAAACCCACCGAAAACGCGTCCACCACACCAGCTTTCACATTCGCCAGGGCCTCGTCGCCGTCCGGGGTGTTCGCAAGCTCGAACGCCCCGAACAAGCCGTGAGGCTCCTCACGCAGCTCGACGGCCCGGCCAACCGGGTAGCGGGTTCGAGCGTCGTGGGAGACCAGCAGCTTCACCTTGTGGCCGCGCTCAGCGATGGAGCGCCGAAAAGCGCCAGGAGCGAACATTTCCCGGAACTCGCCGTCGAGGTCGCGGACGGTGGTCACCTCGCCATAAGGCACGATGACGCCGTACACGGTGCGGCCCTCACCAGGCCGCAGCTCGGCCGTGCGGAAAAGGATGCTACTCAAAATTCGGCCACCGCCTAGCAGACGCAAGAAACGCGCGGAATCGCTTGTGGCGCATGGCGGCCGCTATCCGGGTTCCAGCCGCCCCGCGGCGACTGCCCGGCGTCGGCGGATGCCGAGATGCCAAACTCGATTGTATCACACACAAAAGGTCATCACCGGTCTGGGGCGAACGGGTTGAACTCGTCGTCGTCGGGGTCCCCCGCCGCCGCCAGCACAGCAGCCAAATTCGCCTCAGCGCTTGGCGTGCACCCCAATTCGCGCGCGAGCACCAAAACGTCCCTCGTCGCGGCCCGGGCCGCGGCCACGGCAGGATGCACCGTCACCCGTCGGCTGCGGGCGTTCGTCGCGATGAAACCCTGTTCACGGTAGGCTGTTACAGCCTGCATGAGCTGATCCCAGGCGACGCAGAAGGAGGTCAGCACCCCAAGGTCGGACTCCTTCAGCAGGTTTAATGCCGCAAGCTCGGGAACGACGCGCCCCCACATGTCTTTAGCGCCTGGCGGCAACCAATCCGGGCATTCCGGCGCAACACGCTCGAACGCCGCCGGTGGTGTAACCCGCCGGCCGCCAGAATCACGGCCCGGCGAGCGGCCGCCGAGGAGTTTCAACTGCGCCGGCGCCGGCGCGGGACCACGCCTACCCATTTTCAACACCACCCTCCTCTTTCCGGGTTTCGGGTCGCGAATGCCATGATGCCAAAAAACGCCCCATAAAACTTGAGCGCGCACACGCTCTCCCACCGTGGCGGTGTCCGGTCGGGCGGTTGCTGGCGATGGCAACCCACCCCCCCTACCTGCGGGTTTCGGGTTTTCACTGTTTGCTGTCGGGTTCGTCGGGGAAGTGATACGGATGCCAGCCGAGCTTCATCCCCGCCTCAAGCCGGCGCTGCTCATCGTCGAGATGCATCGACAACAGCGCCAGTTCGGCTGTGTCGTCGTCGATTTCGTGTGATGTCGCCACCATCTCGGCGTACGCTCGGCGGATAGCCTCGAGGTCGCGCTGCCGTTGGGCGCGGCGCTGCTCGGCGGACGGAACGTCGGCCGGCCAACCATGTTGCCGCCCAACGCGATTCCGACGCGGGGCGTTGAGCCCTGCGGCGATGGCTGGCTGGCGTTTAGTGCGCTTGTGGGTCAATGATGGGCTCCTTTCTCCCTGGAAAATGATGTGATCGACGGTGTTCCGGGTGTCCGACAGTCGGGTTCTCTCGGCGGGCTCACGGCGGATCACCCCGGTCGACGGCCGCCGCCGCGGCGGCCGTCGCGGCGAACAAAACGGCCGCGACGCCGTGCGACTCCGCCACAGCGCGGACCAACGCTCGCGCAAGCTCGACGGCCGCGGTCCGCCATGCGCCCGCGGCGTCGCCGGCCAGCGCGGCGGCCGAAGCCTCGACTGGCGGGCCGCCGACAAGCTCGTCCGCGGCGGCCAGCAACGTCCGAGCAGCCAACGCGTGGCCGCTCATCGGGCGCCGTCCCGAGCGCTAGCCGCCGCTCGACCTCGGCAGGGCCGGCATTTGCCGGCGGCCTTGGCCTCAGTACTGAGGAGCTTGTTGGGGCATCCCGGCCCGGAGCACAGCGGCGCGTCGCCGTTGGGGTGCCCGTTGGGCGCCGGCGGCTCGTACGGCAAGTCGCCCGCCTCCGGGAGATCGGTTGCATCGGTTGCGCCGGTTGCATCACCGGGATCGCCAACCGGCGGTGAAACCGCGGAAACCGCGGAAACCGATAAATCTCGTTCCTCGGGGGTTTCGTCGTCGGCAGAGAGATACCGGGACCACGCATCCTCGAACTGGGTCCGCGAATACCCTTTGTAGGGTGGTTCGCCACCACTGTGCTGGAACTTCGGCCCGATGCCGTATCTGCCGAGCCGGGTCGCGAGGCCGCGCGCGTCGAGCGGGTCGCCGCGGCGGATGGAGCCCCACGGTCCCTCCTCCATCCGGTTCAGTCCGGTCAGGATGTCGCTGGTGCGCATCCGGTCCCGGTCGCTGAAGACTCGACGGATATCCCGCAGCAGCAGCACGCCTATGCTGGGCTTGGCTCCTCGATTTGCGGTTGCATCCGTTTCTGCGGTTGCACGGGCGGTTTTGGGCCAGTGCCCGCCCGCGGTGTCAGCAACCGCAACCAGGGACTCCCAGACGTCGGCGCGCCGGTCGGTCACCCCGTCCGGCATCGCCGGCCAACCGCTTTCCAGCGGGTTAATGGCGGCCGCCCAGTTCGCCAACCGGTCGTGCAGCTTCTCGGCCTCGGGGCCGTTGACGCGGGGGCGCCACGGCTCCACGGGTTCGGTTGGTGCCCTCCTGCGCATCCTCACCACGATCGACCGAGACATGATGGTGTCGGGCAGGTCGTCGAGGCCGGCCAAGGCGACCGCACAGTACGCTGGCAGTTCCTCGGTCTCAACGATCTTGCCGCGGATGACGCAGCGGCCCGCGACGGCTCCCTTGCGGTGGCCGGCGTTGATCACGCCGCGAATTTCCTCGTGTTCTTTAGCTTTCGGGCCAAACAGGGTGTCACACTCGTCGTACAGGACGGTCGGCCGCCCGACCGGATCGGCCACCCGACGGAACAGGTAGGCCGGTGTGCAGTTGATGGCATGCACCGGCCGGGGCACTAGCGGTTCCGTGACTTCGAGTGCGCGGCTCTTGCCAGAGCCGGGTTCCGGTGACAAAAAAGCGATTCGGGGCGTTGAGTCCCACGCCTCCATAAACCAGCAATGCGCAATCCAGAGGGTGTGCGCGATCAGTTCATGGTCGCTTGGATAGACTACGAACCGCCGCAAGAATGCCCTAATGTCGTCGAGCAATTCGGCGCCGACCGGCGGCATCGGCTGGCCGTCCTCGTCACACCAGATCGGGTCGGGATAGTCACGGCCGTAGGGGATGTCAGCCATCTCAGACCACCACCCGCCGAATGTAGGCGTCACGCCGACGCTGGATCTCCCGAGAGACCGCCGGCCAGTCGGCGGCGGCGGATACGTCACGTGATGCCTCGGCCGACGCGGCCTGGCACGTCTCCACCCGGAGTGCCCAATGCCGAGCAGCGTCGCAGATCGCGGCCCATTTGACCGGGTCGGTGTCGTCGAGGTCGCACCACGCCGGGGTGCCGGCCATCGGCCATTCCACGGCGGCGGCCAGGGTCGGTGCGACATACTCGTGCACCGACCACCACGACACGGCGCGGGACGCGGTAGGATCGGTGCTAGACGGTGTGGCGACTGTCGCGGGTGCCCGGTCCTCTGTGGCCGGGCATCGTCGCGTCGGCGGCGACCCGCCGACGGCGGTCATGCGGCACCACCGAACGGGTGCATGGCGCCGTCGACCTCATCGCGGCGCAGACGGACGAGGCGGGTGCCGGAGCGGTATCCGCGTAGGCGGCCGTCGGCGATCATCTGGCGGACCGTGCGGTCGGTGACCGCTAGATATTCGGCGGCCTCACTGATCGTGATGTACCGCCGTGACAACGGGGGAGCGTCTGCCATGCCGGGCCTTTCGGTCTCGTGAGAGACCGTCCACCCGAGACTCGGCGACGGGAACGCGCACATGCGCGCACCGGAAAATTTACCCGCCTAGCTGGCTCAAGCGCAAGCATAATGCGCTGAACGGAATTACGTGTCGCGCCTCTGCTATTGATGGATCGTCAGCGTCGGGGATGGTCGACGTTCTCAGCTCGTGAAGCTTCGCCCCGAAACCGTCGAGGATCGCCGCGGCGGTCATCTCGGATATCGGCGCATACTTTCGGCATGCCCGGCATTCGAGTTTCCACTCGATATGGCGGCCCCACTGTGTTTCGGTGAAGCGGGTGTTCGACCGCATCTGTATGTGCCCGCCGGCGGGTCGTTCGTCGTCGATCCAGGCGATGATGAGCGCTCCCGGTTCGTCGTCGCAGTTGCACATAACTACGTACTTAACCGCATCGGCCATCATCACATCTCCTGGTTCTCGGCCAGTTTGCTTAACAGTGCGGCGATTTCGCGGTCCCGGCCCTTGGCGGCGTGCTGGTAGCGGAGTGCGGCGCCGGCTGTGCTGTGTCCTAGCCGCTGCATCAGTTCGGCCAGTGTGGCGCCGGTGGATGCAGCCAACACGGCGCCGGAGTGTCGAAGGTCGTGCACCCGTAAGTCTGGTCGGCCGGCGGCTTTTCGGGCCTTGTAGAACATGCGGTACAGCGCCGAGGGTGCTAGGTGACGGTTGGGGTCGTTGACCGATGGGAACAGCAGGGACTCCCGGCCGGGGTTGACGTGTTTGTGAAGGTGGTCTTCGATGGCGGGTATCAGATGTGGCGGGATACTTATGTCGCGCACTCCCGCATCGCTTTTCGGTGTCGTCACCTTGAAGCCTTCGCCCACCCGAACGACAGCCCGCCGCACCCGCGCAACCTCGCCGTGCAGGTCGATGTCTTTGCGGCGTAATTCGGTCAGCTCGCCGTAGCGCATGGCCAGCCATGCCGCCATCAGCACGAACGCCTGGTAGGGGTCGGGCATGGCTTTGGTGATGGTTTCCAGCTCGTCGAGGGTGGCGGGCCTGATCTTGTGGACGCGGCGGGCGGTGGACGCGCCTGAGATGCGGCAGGGGTTGGAGTCGATCAGGTCGTCGGCCAAGGCGGTCTGCATGATTGCGCGCAGCAAGCTGTAGGAGTGTGCCCGCATGGTCGGTGTGCCCACGGCGGTGGTGGCGTACCAGCGGCGCACGGCGGCCGGGGTGATGTCGCGTAGGTCGGTGTCAGCGAAGGTGGCCAGGATGTGGTTGTCCAGCAGTTTGCGATAGTGGGCGCGGGTGCGGTCCTTGATTCCACGCTGCTTCAGCCATCCTTCGGCGTACTCACCGAATGGGGCTCCGGGGCGGTCTTCCTGACCCGATGCCGGGGACCATAGTTGTCGGTCGATTTCGCGGCGGCGGTCGGTGAGCCATGCTTCGGCGTCGATCTTGGCGTTGAAGGTTTTGGGGGCGATGTACACGCGGCCGTCGGGGCCGGTGTAGCTGGCTTGCCAGCGGCCGGAGTTGAACTGTCGGATGCGACCGAATTTGCGTCTCTGACGCTTGCCGGTTTGCGTCAC

Protein sequences of DBSCAN-SWA_1

>NC_021251|2935721:2973994|2937908_2938136_+|WP_003413487.1|DBSCAN-SWA
MGDRYRAGDRVLYGGSMSPKDVDDLATQQDVDDGQSIERRWTGSGQRRWRRSPPTGRYRSNSQIQVWISGAGRLR
>NC_021251|2935721:2973994|2953441_2953723_-|WP_003413619.1|DBSCAN-SWA
MTDSEHVGKTCQIDVLIEEHDERTRAKARLSWAGRQMVGVGLARLDPADEPVAQIGDELAIARALSDLANQLFALTSSDIEASTHQPVTGLHH
>NC_021251|2935721:2973994|2940379_2940820_-|WP_003413574.1|DBSCAN-SWA
MSIRPTTSPALADQLKDPAYSAYVLLRTLFTVAPILFGLDKFFNLLTHPQHWNMYLAGWINDLVPGTADQCMYLVGAIEIVAGVLVAVAPRIGAWVVAAWLAGIILNLVTGPGFYDIALRDFGLLVGAIALARLAQGVHSGGIGRP
>NC_021251|2935721:2973994|2949590_2949953_+|WP_003899403.1|DBSCAN-SWA
MSTQRPRHSGIRAVGPYAWAGRCGRIGRWGVHQEAMMNLAIWHPRKVQSATIYQVTDRSHDGRTARVPGDEITSTVSGWLSELGTQSPLADELARAVRIGDWPAAYAIGEHLSVEIAVAV
>NC_021251|2935721:2973994|2969761_2970085_-|WP_003899414.1|DBSCAN-SWA
MTHKRTKRQPAIAAGLNAPRRNRVGRQHGWPADVPSAEQRRAQRQRDLEAIRRAYAEMVATSHEIDDDTAELALLSMHLDDEQRRLEAGMKLGWHPYHFPDEPDSKQ
>NC_021251|2935721:2973994|2943168_2943990_+|WP_003413589.1|DBSCAN-SWA
MANKRGNAGQPLPLSDRDDDHMQGHWLLARLGKRVLRPGGVELTRTLLARAEVTDADVLELAPGLGRTAAEILARNPRSYVGAESDPNAANLVRHVLAGRGDVRVTDAADTGLSDASADVVIGEAMLTMQGNAAKHTIVAEAARVLRPGGRYAIHELALVPDDVAEQVRTDLRQSLARALKVNARPLTVAEWSHLLAGHGLVVEHVVTASMALLQPRRVIADEGLLGALRFAGNLLIHRAARRRVLLMRHTFRRHRERLTAVAIVAHKPHVDS
>NC_021251|2935721:2973994|2952104_2953403_+|WP_003413616.1|DBSCAN-SWA
MQVVNVATLPGIVRASYAMPDVHWGYGFPIGGVAATDVDNDGVVSPGGVGFDISCGVRLLVGEGLDREELQPRLPAVMDRLDRAIPRGVGTAGVWRLPDRNTLQEVLTGGARFAVEQGHGVALDLERCEDGGVMTGADAAKISDRALQRGLGQIGSLGSGNHFLEVQAVDRVYDPVAAAPMGLAEGTVCVMIHTGSRGLGHQICTDHVRQMEQAMGRYGIAVPDRQLACVPVHSPDGQAYLAAMAAAANYGRANRQLLTEATRRVFADATGTPLDLLYDVSHNLAKIETHPIDGQLRSVCVHRKGATRSLPPHHHELPAELAAVGQPVLIPGTMGTASYVLAGVTGNPAFFSTAHGAGRVLSRHQAARHTSGEAIRASLAKRGIIVRGTSRRGIAEEKPEAYKDVDEVIEASHQSGLARKVARLVPLGCVKG
>NC_021251|2935721:2973994|2970406_2971834_-|WP_003899416.1|DBSCAN-SWA
MADIPYGRDYPDPIWCDEDGQPMPPVGAELLDDIRAFLRRFVVYPSDHELIAHTLWIAHCWFMEAWDSTPRIAFLSPEPGSGKSRALEVTEPLVPRPVHAINCTPAYLFRRVADPVGRPTVLYDECDTLFGPKAKEHEEIRGVINAGHRKGAVAGRCVIRGKIVETEELPAYCAVALAGLDDLPDTIMSRSIVVRMRRRAPTEPVEPWRPRVNGPEAEKLHDRLANWAAAINPLESGWPAMPDGVTDRRADVWESLVAVADTAGGHWPKTARATAETDATANRGAKPSIGVLLLRDIRRVFSDRDRMRTSDILTGLNRMEEGPWGSIRRGDPLDARGLATRLGRYGIGPKFQHSGGEPPYKGYSRTQFEDAWSRYLSADDETPEERDLSVSAVSAVSPPVGDPGDATGATDATDLPEAGDLPYEPPAPNGHPNGDAPLCSGPGCPNKLLSTEAKAAGKCRPCRGRAAASARDGAR
>NC_021251|2935721:2973994|2969103_2969730_-|WP_003899413.1|terminase|DBSCAN-SWA
MPSPATARPDTATVGERVRAQVLWGVFWHHGIRDPKPGKRRVVLKMGRRGPAPAPAQLKLLGGRSPGRDSGGRRVTPPAAFERVAPECPDWLPPGAKDMWGRVVPELAALNLLKESDLGVLTSFCVAWDQLMQAVTAYREQGFIATNARSRRVTVHPAVAAARAATRDVLVLARELGCTPSAEANLAAVLAAAGDPDDDEFNPFAPDR
>NC_021251|2935721:2973994|2941628_2941982_-|WP_003413583.1|DBSCAN-SWA
MESISLTSLAAEKLAEAQQTHSGRAAHTIHGGHTHELRQTVLALLAGHDLSEHDSPGEATLQVLQGHVCLTAGEDAWNGRAGDYVAIPPTRHALHAVEDSVIMLTVLKSLPDAHSGS
>NC_021251|2935721:2973994|2947094_2947526_-|WP_003413598.1|DBSCAN-SWA
MTTARDIMNAGVTCVGEHETLTAAAQYMREHDIGALPICGDDDRLHGMLTDRDIVIKGLAAGLDPNTATAGELARDSIYYVDANASIQEMLNVMEEHQVRRVPVISEHRLVGIVTEADIARHLPEHAIVQFVKAICSPMALAS
>NC_021251|2935721:2973994|2957003_2957246_+|WP_003899405.1|DBSCAN-SWA
MVAADHRALGSNKSYPASQTAEAIWPPARTLRYDRQSPWLATGFDRRMSQTVTGVGVQNCAVSKRRCSAVDHSSRTPYRR
>NC_021251|2935721:2973994|2945854_2947036_-|WP_003899401.1|protease|DBSCAN-SWA
MRDAIPLGRIAGFVVNVHWSVLVILWLFTWSLATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHAVVARRAGVSVESVTLWLFGGVTALGGEAKTPKAAFRIAFAGPATSLALSATFGALAITLAGVRTPAIVISVAWWLATVNLLLGLFNLLPGAPLDGGRLVRAYLWRRHGDSVRAGIGAARAGRVVALVLIALGLAEFVAGGLVGGVWLAFIGWFIFAAAREEETRISTQQLFAGVRVADAMTAQPHTAPGWINVEDFIQRYVLGERHSAYPVADRDGSITGLVALRQLRDVAPSRRSTTSVGDIALPLHSVPTARPQEPLTALLERMAPLGPRSRALVTEGSAVVGIVTPSDVARLIDVYRLAQPEPTFTTSPQDADRFSDAG
>NC_021251|2935721:2973994|2938132_2939518_-|WP_009940032.1|DBSCAN-SWA
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQERFVLALSQAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGNGGIGGAGTNLAIGGHGGNGGNAGLIGAGGTGGAGGTGGGEPSAGASGGNGGNGGNGGLLIGNSGDGGAAGNGAGISQNGPASGFGGNGGHAGTTGLIGNGGNGGAGGAGGDVSADFGGVGFGGQGGNGGAGGLLYGNGGAGGNGGAAGSPGSVTAFGGNGGSGGSGGNGGNALIGNAGAGGSAGAGGNGASAGTAGGSGGDGGKGGNGGSVGLIGNGGNGGNGGAGSLFNGAPGFGGPGGSGGASLLGPPGLAGTNGADG
>NC_021251|2935721:2973994|2945021_2945840_-|WP_003413594.1|DBSCAN-SWA
MSGRGEPTMKTIIVGIDGSHAAITAALWGVDEAISRAVPLRLVSVIKPTHPSPDDYDRDLAHAERSLREAQSAVEAAGKLVKIETDIPRGPAGPVLVEASRDAEMICVGSVGIGRYASSILGSTATELAEKAHCPVAVMRSKVDQPASDINWIVVRMTDAPDNEAVLEYAAREAKLRQAPILALGGRPEELREIPDGEFERRVQDWHHRHPDVRVYPITTHTGIARFLADHDERVQLAVIGGGEAGQLARLVGPSGHPVFRHAECSVLVVRR
>NC_021251|2935721:2973994|2950299_2951424_+|WP_003902322.1|DBSCAN-SWA
MRSERLRWLVAAEGPFASVYFDDSHDTLDAVERREATWRDVRKHLESRDAKQELIDSLEEAVRASRPAVGQRGRALIATGEQVLVNEHLIGPPPATVIRLSDYPYVVPLIDLEMRRPTYVFAAVDHTGADVKLYQGATISSTKIDGVGYPVHKPVTAGWNGYGDFQHTTEEAIRMNCRAVADHLTRLVDAADPEVVFVSGEVRSRTDLLSTLPQRVAVRVSQLHAGPRKSALDEEEIWDLTSAEFTRRRYAEITNVAQQFEAEIGRGSGLAAQGLAEVCAALRDGDVDTLIVGELGEATVVTGKARTTVARDADMLSELGEPVDRVARADEALPFAAIAVGAALVRDDNRIAPLDGVGALLRYAATNRLGSHRS
>NC_021251|2935721:2973994|2964656_2965088_+|WP_003899409.1|DBSCAN-SWA
MTTTPRQPLFCAHADTNGDPGRCACGQQLADVGPATPPPPWCEPGTEPIWEQLTERYGGVTICQWTRYFPAGDPVAADVWIAADDRVVDGRVLRTQPAIHYTEPPVLGIGPAAARRLAAELLNAADTLDDGRRQLDDLGEHRR
>NC_021251|2935721:2973994|2948039_2949281_-|WP_003899402.1|DBSCAN-SWA
MASSASDGTHERSAFRLSPPVLSGAMGPFMHTGLYVAQSWRDYLGQQPDKLPIARPTIALAAQAFRDEIVLLGLKARRPVSNHRVFERISQEVAAGLEFYGNRGWLEKPSGFFAQPPPLTEVAVRKVKDRRRSFYRIFFDSGFTPHPGEPGSQRWLSYTANNREYALLLRHPEPRPWLVCVHGTEMGRAPLDLAVFRAWKLHDELGLNIVMPVLPMHGPRGQGLPKGAVFPGEDVLDDVHGTAQAVWDIRRLLSWIRSQEEESLIGLNGLSLGGYIASLVASLEEGLACAILGVPVADLIELLGRHCGLRHKDPRRHTVKMAEPIGRMISPLSLTPLVPMPGRFIYAGIADRLVHPREQVTRLWEHWGKPEIVWYPGGHTGFFQSRPVRRFVQAALEQSGLLDAPRTQRDRSA
>NC_021251|2935721:2973994|2972866_2973994_-|WP_003899420.1|integrase|DBSCAN-SWA
MTQTGKRQRRKFGRIRQFNSGRWQASYTGPDGRVYIAPKTFNAKIDAEAWLTDRRREIDRQLWSPASGQEDRPGAPFGEYAEGWLKQRGIKDRTRAHYRKLLDNHILATFADTDLRDITPAAVRRWYATTAVGTPTMRAHSYSLLRAIMQTALADDLIDSNPCRISGASTARRVHKIRPATLDELETITKAMPDPYQAFVLMAAWLAMRYGELTELRRKDIDLHGEVARVRRAVVRVGEGFKVTTPKSDAGVRDISIPPHLIPAIEDHLHKHVNPGRESLLFPSVNDPNRHLAPSALYRMFYKARKAAGRPDLRVHDLRHSGAVLAASTGATLAELMQRLGHSTAGAALRYQHAAKGRDREIAALLSKLAENQEM
>NC_021251|2935721:2973994|2972501_2972864_-|WP_003900543.1|DBSCAN-SWA
MADAVKYVVMCNCDDEPGALIIAWIDDERPAGGHIQMRSNTRFTETQWGRHIEWKLECRACRKYAPISEMTAAAILDGFGAKLHELRTSTIPDADDPSIAEARHVIPFSALCLRLSQLGG
>NC_021251|2935721:2973994|2961066_2961447_+|WP_003899407.1|DBSCAN-SWA
MSNLHPLPEVASCVVAPLVREPLNPPAAAEMAARFKALADPVRLQLLSSVASRAGGEACVCDISAGVEVSQPTISHHLKVLRDAGLLTSRRRASWVYYAVVPEALTVLSNLLSVHADAAPALGAPA
>NC_021251|2935721:2973994|2970164_2970410_-|WP_003899415.1|DBSCAN-SWA
MSGHALAARTLLAAADELVGGPPVEASAAALAGDAAGAWRTAAVELARALVRAVAESHGVAAVLFAATAAAAAAVDRGDPP
>NC_021251|2935721:2973994|2944125_2945019_+|WP_003413592.1|DBSCAN-SWA
MSSGNSSLGIIVGIDDSPAAQVAVRWAARDAELRKIPLTLVHAVSPEVATWLEVPLPPGVLRWQQDHGRHLIDDALKVVEQASLRAGPPTVHSEIVPAAAVPTLVDMSKDAVLMVVGCLGSGRWPGRLLGSVSSGLLRHAHCPVVIIHDEDSVMPHPQQAPVLVGVDGSSASELATAIAFDEASRRNVDLVALHAWSDVDVSEWPGIDWPATQSMAEQVLAERLAGWQERYPNVAITRVVVRDQPARQLVQRSEEAQLVVVGSRGRGGYAGMLVGSVGETVAQLARTPVIVARESLT
>NC_021251|2935721:2973994|2958119_2958776_+|WP_003413654.1|DBSCAN-SWA
MDVEALLQSIPPLMVYLVVGAVVGIESLGIPLPGEIVLVSAAVLSSHPELAVNPIGVGGAAVIGAVVGDSIGYSIGRRFGLPLFDRLGRRFPKHFGPGHVALAERLFNRWGVRAVFLGRFIALLRIFAGPLAGALKMPYPRFLAANVTGGICWAGGTTALVYFAGMAAQHWLERFSWIALVIAVIAGITAAILLRERTSRAIAELEAEHCRKAGTTAA
>NC_021251|2935721:2973994|2959559_2959892_-|WP_003413663.1|DBSCAN-SWA
MVVRSILLFVLAAVAEIGGAWLVWQGVREQRGWLWAGLGVIALGVYGFFATLQPDAHFGRVLAAYGGVFVAGSLAWGMALDGFRPDRWDVIGALGCMAGVAVIMYAPRGH
>NC_021251|2935721:2973994|2953867_2954353_-|WP_003413625.1|DBSCAN-SWA
MNAYDVLKRHHTVLKGLGRKVGEAPVNSEERHVLFDEMLIELDIHFRIEDDLYYPALSAAGKPITGTHAEHRQVVDQLATLLRTPQRAPGYEEEWNVFRTVLEAHADVEERDMIPAPTPVHITDAELEELGDKMAARIEQLRGSPLYTLRTKGKADLLKAI
>NC_021251|2935721:2973994|2935721_2937800_-|WP_003413486.1|tRNA|DBSCAN-SWA
MSAPAQPAPGVDGGDPSQARIRVPAGTTAATAVGEAGLPRRGTPDAIVVVRDADGNLRDLSWVPDVDTDITPVAANTDDGRSVIRHSTAHVLAQAVQELFPQAKLGIGPPITDGFYYDFDVPEPFTPEDLAALEKRMRQIVKEGQLFDRRVYESTEQARAELANEPYKLELVDDKSGDAEIMEVGGDELTAYDNLNPRTRERVWGDLCRGPHIPTTKHIPAFKLTRSSAAYWRGDQKNASLQRIYGTAWESQEALDRHLEFIEEAQRRDHRKLGVELDLFSFPDEIGSGLAVFHPKGGIVRRELEDYSRRKHTEAGYQFVNSPHITKAQLFHTSGHLDWYADGMFPPMHIDAEYNADGSLRKPGQDYYLKPMNCPMHCLIFRARGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRVRGLTMDDAHIFCTRDQMRDELRSLLRFVLDLLADYGLTDFYLELSTKDPEKFVGAEEVWEEATTVLAEVGAESGLELVPDPGGAAFYGPKISVQVKDALGRTWQMSTIQLDFNFPERFGLEYTAADGTRHRPVMIHRALFGSIERFFGILTEHYAGAFPAWLAPVQVVGIPVADEHVAYLEEVATQLKSHGVRAEVDASDDRMAKKIVHHTNHKVPFMVLAGDRDVAAGAVSFRFGDRTQINGVARDDAVAAIVAWIADRENAVPTAELVKVAGRE
>NC_021251|2935721:2973994|2940966_2941644_+|WP_003901437.1|DBSCAN-SWA
MDPVRRQLYQFVCSQSMPVSRDQAADAVGIPRHQAKFHLDRLTAEGLLDTEYARLTGRSGPGAGRTAKLYRRAGRDIALSLPQREYELAGRLMAAAIVLSATTGEPTVEVLNRIAHDYGQAMGAAATTRPPADPAAALELTLDVLRKYGYEPRRPAGPGDDEVELVNCPFHALAREQTELACNMNHALITGVADALAPHSPAVRLAPGPARCCVVLKRCSAHDPE
>NC_021251|2935721:2973994|2968417_2968951_-|WP_003899412.1|head,protease|DBSCAN-SWA
MSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW
>NC_021251|2935721:2973994|2966970_2968410_-|WP_003901443.1|capsid|DBSCAN-SWA
MTTEQHFADDGDIKQLSLDETRSAAKQLLDSVEGDLTGDVAQRFQALTRHAEELRAEQRRRGREAEEALRRCRAGELRVVPGAPTGGDDGDAPPGNSLRDTAFRTLDVCVRDGLMSSRAAEAAETLCRTGPPQSTSWAQRWLAATGNRDYLGAFVKRVSNPVAGHTTWTDREAAAWREAAAVAAEQRAMGLVDTAGGFLIPAALDPAILLSGDGSTNPIRQVARVVQTTSEVWRGVTSEGAEAHWYSEAQEVSDDSPTLAQPAVPSYRGSCWIPFSLEIEGDAAGFVAEVGRVLADSVEQLQAAAFVSGSGNGEPTGFVSALTGTADYTVTGAGTEAVVAADVYALQSALPPRFQSNSAFAANLSTINVLRQAETANGALKFPSLHASPPMLAGKHIWEVSNMDTVDAAVTATNYPLVLGDWKQFIITDRVGSTVELVPHVFGGNRRPTGQRGFFCWFRVGSDVLVDNAFRVLKVQTTA
>NC_021251|2935721:2973994|2960472_2960931_+|WP_003413675.1|DBSCAN-SWA
MSRVQLALNVDDLEAAITFYSRLFNAEPAKRKPGYANFAIADPPLKLVLLENPGTGGTLNHLGVEVGSSNTVHAEIARLTEAGLVTEKEIGTTCCFATQDKVWVTGPGGERWEVYTVLADSETFGSGPRHNDTSDGEASMCCDGQVAVGASG
>NC_021251|2935721:2973994|2971835_2972228_-|WP_003899417.1|DBSCAN-SWA
MTAVGGSPPTRRCPATEDRAPATVATPSSTDPTASRAVSWWSVHEYVAPTLAAAVEWPMAGTPAWCDLDDTDPVKWAAICDAARHWALRVETCQAASAEASRDVSAAADWPAVSREIQRRRDAYIRRVVV
>NC_021251|2935721:2973994|2942416_2943091_-|WP_003901438.1|DBSCAN-SWA
MGVSVIIRSLQEPVGRRRAVLRALCASRVPMSIAAIAGKLGVHPNTVRFHLDNLVADGQVERVEPGRGRPGRPPLMFRAVRRTDSTGTRRYRLLAEILASGLAAERDSRVMALSAGRAWGRQLEAPPAGADTEETIDHLVAVLDDLGFAPERRASNGRQQVGLRHCPFLELAETQAGVVCPVHLGIMRGALQTWGAPVTVDRLDAFVEPDLCLAHFTPLEGAIR
>NC_021251|2935721:2973994|2941994_2942420_-|WP_003413586.1|DBSCAN-SWA
MSAGPAIEVAVAFVWLGMVVAISFLEAPLKFRAAGVTLQIGLGIGRLVFRALNTVEVGFALVILAIVVVGSTPARIAAAFSVALAALAVQLIAVRPRLTRRSNQVLAGLQAPRSRGHHIYVGLEIVKVVALLVAGILLLNG
>NC_021251|2935721:2973994|2957246_2957924_+|WP_003899406.1|DBSCAN-SWA
MINPTRARRMRYRLAAMAGMPEGKLILLNGGSSAGKTSLALAFQDLAAECWMHIGIDLFWFALPPEQLDLARVRPEYYTWDSAVEADGLEWFTVHPGPILDLAMHSRYRAIRAYLDNGMNVIADDVIWTREWLVDALRVFEGCRVWMVGVHVSDEEGARRELERGDRHPGWNRGSARAAHADAEYDFELDTTATPVHELARELHESYQACPYPMAFNRLRKRFLS
>NC_021251|2935721:2973994|2939862_2940363_+|WP_003413569.1|DBSCAN-SWA
MDLNALADLPLTYPEVGATATGRLPAGYNHLDVSTQIGTGRQRFEQAADAVMHWGMQRNAGLRVRASSETAVVSAVVLVGIAFLRAPCRVVYVIDEPDVRGFGYGTLPGHPVSGEERFAVRCDPMTSVVFAEVLSFSRPATWASKAAGPLGAVTQRFIAQRYLRAV
>NC_021251|2935721:2973994|2958938_2959385_+|WP_003413657.1|DBSCAN-SWA
MGLITTEPRSSPHPLSPRLVHELGDPHSTLRATTDGSGAALLIHAGGEIDGRNEHLWRQLVTEAAAGVTAPGPLIVDVTGLDFMGCCAFAALADEAQRCRCRGIDLRLVSHQPIVARIAEAGGLSRVLPIYPTVDTALGKGTAGPARC
>NC_021251|2935721:2973994|2954379_2954637_-|WP_003902325.1|DBSCAN-SWA
MLPLGANITLAELPEPELRQLFPHEELQIPVSCGGLGAGAGGRMDMRAVGLVPVRRASRYCTGFFVLIHSYLTLMGRGARLRLSR
>NC_021251|2935721:2973994|2961443_2962940_+|WP_003413686.1|DBSCAN-SWA
MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALEGVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWVLGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAAAVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLIFLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFALQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAFTAASNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALRNRLAGPNATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRSAGTEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGDACPYFPGVSYRNWKLPDPAGQPLDVVRMIRDDIADRVQALIAELLATAKTR
>NC_021251|2935721:2973994|2960011_2960371_-|WP_003413665.1|DBSCAN-SWA
MPKSLPVIDISAPVCCAPVAAGPMSDGDALAVALRLKALADPARVKIMSYLFSSPAGEQVSGQLAAALSLSDGTVSHHLAQLRKAGLVISDRRGMHVFHRVHPEALQALCTVLNPNCCA
>NC_021251|2935721:2973994|2966096_2966561_+|WP_003900539.1|DBSCAN-SWA
MLQPIGVTPDRRLVFGQRRLEAARLLGWERIPVHVCHTIADVVDRAKAERSENTLRKDFTPSELLAAGRRIAELERPKAKQRQREGGDHGRQARYSGLGSMEPKPESERDAHKADTAISEALGISRGHYQRLKRIDNATRSEAGYRDGLNGWSG
>NC_021251|2935721:2973994|2966548_2966800_+|WP_003908028.1|DBSCAN-SWA
MERLTAGARDGPRRQLVQRATLTSTLAQLIFGGLACLLSLAAPSLIATPNLPLNRALHTHPELILDTLLLPNPTLKLTPVVVD
>NC_021251|2935721:2973994|2963174_2963366_+|WP_003912823.1|DBSCAN-SWA
MRRYRERLRQRGLRPIQIWVPDVNAPEFVGEAHRPSALVAAREYEDDDQAFVDAVSVDWDDAT
>NC_021251|2935721:2973994|2963438_2963612_+|WP_077365235.1|DBSCAN-SWA
MQNDRFDSTASVTVVPFTTRDVQASLMRIPAPASNTTGLTETSRLTVDKVTTSPAPA
>NC_021251|2935721:2973994|2965084_2966083_+|WP_003900538.1|integrase|DBSCAN-SWA
MNTATRVRLARKRADRLNLKLIKNGHHFRLRDADEITLAVGHLGVVEAFLAAAKSQNKPPGPPPSLHAPPSWRRDIDDYLLNLNAAGQRPATIRLRKTVLCAAAHGLGRPPADVTAEHLLDWLGKQQHLSPEGRKTYRSTLRGFFVWAYEMDRVRDYVADSLPKVRCPKQPPRPAGDDVWQAALAKADRRIELMIRLAGEAGLRRAEAAQAHTGDLMDGGLLLVHGKGGKRRIVPISDYLAALIRDTPHGYLFPNGTGGHLTAEHVGKLVSRALPGDATMHTLRHRYATRAYRGSHNLRAVQQLLGHASIVTTERYTALCDDEVRAAAAAAW
>NC_021251|2935721:2973994|2972224_2972485_-|WP_003899418.1|DBSCAN-SWA
MCAFPSPSLGWTVSHETERPGMADAPPLSRRYITISEAAEYLAVTDRTVRQMIADGRLRGYRSGTRLVRLRRDEVDGAMHPFGGAA
>NC_021251|2935721:2973994|2951425_2951965_+|WP_003413614.1|DBSCAN-SWA
MLHRDDHINPPRPRGLDVPCARLRATNPLRALARCVQAGKPGTSSGHRSVPHTADLRIEAWAPTRDGCIRQAVLGTVESFLDLESAHAVHTRLRRLTADRDDDLLVAVLEEVIYLLDTVGETPVDLRLRDVDGGVDVTFATTDASTLVQVGAVPKAVSLNELRFSQGRHGWRCAVTLDV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003413486.1|2935721_2937800_-|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	2.5e-104	34.9
WP_003413487.1|2937908_2938136_+	hypothetical protein	NA	NA	NA	NA
WP_009940032.1|2938132_2939518_-	PE family protein	NA	NA	NA	NA
WP_003413569.1|2939862_2940363_+	DUF1990 family protein	NA	NA	NA	NA
WP_003413574.1|2940379_2940820_-	DoxX family membrane protein	NA	NA	NA	NA
WP_003901437.1|2940966_2941644_+	transcriptional regulator	NA	NA	NA	NA
WP_003413583.1|2941628_2941982_-	cupin domain-containing protein	NA	NA	NA	NA
WP_003413586.1|2941994_2942420_-	hypothetical protein	NA	NA	NA	NA
WP_003901438.1|2942416_2943091_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003413589.1|2943168_2943990_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_003413592.1|2944125_2945019_+	universal stress protein	NA	NA	NA	NA
WP_003413594.1|2945021_2945840_-	universal stress protein	NA	NA	NA	NA
WP_003899401.1|2945854_2947036_-|protease	site-2 protease family protein	NA	NA	NA	NA
WP_003413598.1|2947094_2947526_-	hypoxic response protein Hrp1	A0A2I6B2H4	Macacine_betaherpesvirus	1.9e-75	100.0
WP_003899402.1|2948039_2949281_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003899403.1|2949590_2949953_+	hypothetical protein	NA	NA	NA	NA
WP_003902322.1|2950299_2951424_+	hypothetical protein	NA	NA	NA	NA
WP_003413614.1|2951425_2951965_+	hypothetical protein	NA	NA	NA	NA
WP_003413616.1|2952104_2953403_+	RtcB family protein	A2RQD0	Archaeal_BJ1_virus	3.8e-90	43.3
WP_003413619.1|2953441_2953723_-	DUF1876 domain-containing protein	NA	NA	NA	NA
WP_003413625.1|2953867_2954353_-	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_003902325.1|2954379_2954637_-	hypothetical protein	NA	NA	NA	NA
WP_003899405.1|2957003_2957246_+	hypothetical protein	NA	NA	NA	NA
WP_003899406.1|2957246_2957924_+	membrane protein	NA	NA	NA	NA
WP_003413654.1|2958119_2958776_+	DedA family protein	NA	NA	NA	NA
WP_003413657.1|2958938_2959385_+	anti-sigma factor antagonist	NA	NA	NA	NA
WP_003413663.1|2959559_2959892_-	YnfA family protein	NA	NA	NA	NA
WP_003413665.1|2960011_2960371_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003413675.1|2960472_2960931_+	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_003899407.1|2961066_2961447_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003413686.1|2961443_2962940_+	ACR3 family arsenite efflux transporter	A0A2H4PQT9	Staphylococcus_phage	5.1e-14	39.7
WP_003912823.1|2963174_2963366_+	antitoxin MazE family protein	NA	NA	NA	NA
WP_077365235.1|2963438_2963612_+	hypothetical protein	NA	NA	NA	NA
2964523:2964550	attL	NA	NA	NA	NA
WP_003899409.1|2964656_2965088_+	hypothetical protein	NA	NA	NA	NA
WP_003900538.1|2965084_2966083_+|integrase	tyrosine-type recombinase/integrase	A0A2D1G8E2	Mycobacterium_phage	7.4e-62	47.8
WP_003900539.1|2966096_2966561_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_003908028.1|2966548_2966800_+	hypothetical protein	NA	NA	NA	NA
WP_003901443.1|2966970_2968410_-|capsid	phage major capsid protein	A0A1B3AYS4	Gordonia_phage	1.4e-66	40.6
WP_003899412.1|2968417_2968951_-|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	3.1e-06	32.9
WP_003899413.1|2969103_2969730_-|terminase	phage terminase small subunit P27 family	V9H0V4	Actinophage	1.6e-17	47.2
WP_003899414.1|2969761_2970085_-	type II toxin-antitoxin system toxin	NA	NA	NA	NA
WP_003899415.1|2970164_2970410_-	type II toxin-antitoxin system antitoxin	NA	NA	NA	NA
WP_003899416.1|2970406_2971834_-	DUF3631 domain-containing protein	NA	NA	NA	NA
WP_003899417.1|2971835_2972228_-	DUF2742 domain-containing protein	NA	NA	NA	NA
WP_003899418.1|2972224_2972485_-	helix-turn-helix domain-containing protein	A0A2P1CHK7	Mycobacterium_phage	3.0e-15	64.6
WP_003900543.1|2972501_2972864_-	hypothetical protein	NA	NA	NA	NA
WP_003899420.1|2972866_2973994_-|integrase	site-specific integrase	A0A1X9SFC1	Mycobacterium_phage	1.5e-66	40.4
2974147:2974174	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_021251|3706703:3796139|DBSCAN-SWA
CTCAGCCGGCGGCTGGTCTCTGGCGTTGAGCGTAGTAGGCAGCCTCGAGTTCGACCGGCGGGACGTCGCCGCAGTACTGGTAGAGGCGGCGATGGTTGAACCAGTCGACCCAGCGCGCGGTGGCCAACTCGACATCCTCGATGGACCGCCAGGGCTTGCCGGGTTTGATCAGCTCGGTCTTGTATAGGCCGTTGATCGTCTCGGCTAGTGCATTGTCATAGGAGCTTCCGACCGCTCCGACCGACGGTTGGATGCCTGCCTCGGCGAGCCGCTCGCTGAACCGGATCGATGTGTACAGAGATCCCCTATCCGTATGGTGGATAACGTCTTTCAGGTCGAGTACGCCTTCTTGTTGGCGGGTCCAGATGGCTTGCTCGATCGCGTCGAGGACCATGGAGGTGGCCATCGTGGAAGCGACCCGCCAGCCCAGGATCCTGCGAGCGTAGGCGTCGGTGACAAAGGCCACGTAGGCGAACCCTGCCCAGGTCGACACATAGGTGAGGTCTGCTACCCACAGCCGGTTAGGTGCTGGTGGTCCGAAGCGGCGCTGGACGAGATCGGCGGGACGGGCTGTGGCCGGATCAGCGATCGTGGTCCTGCGGGCTTTGCCGCGGGTGGTCCCGGACAGGCCGAGTTTGGTCATCAGCCGTTCGACGGTGCATCTGGCCACCTCGATGCCCTCACGGTTCAGGGTTAGCCACACTTTGCGGGCACCGTAAACACCGTAGTTGGCGGCGTGGACGCGGCTGATGTGCTCCTTGAGTTCGCCATCGCGCAGCTCGCGGCGGCTGGGCTCCCGGTTGATGTGGTCGTAGTAGGTCGATGGGGCGATCGGCACACCCAGCTCGGTCAGCTGTGTGCAGATCGACTCGACACCCCACCGCAAACCATCGGGGCCCTCGCGGTGGCCCTGATGATCGGCGATGAACCGGGTAATTAGCGTGCTGGCCGGTCGAGCTCGGCCGCGAAGAAAGCCGACGCGGTCTTTAAAATCGCGTTCGCCCTTCGCAATTCGGCGTTGTCCCGCCGCAAGCGCTTCAGCTCAGCGGATTCTTCGGTCGTGGTCCCGGGCCGTGCGCCGGCATCGACCTGCGCCTGGCGCACCCACTTACGCACCGTCTCCGCGCAGCCAACACCAAGTAGACGGGCGACCTCACTGATCGCTGCCCACTCCGAATCGTGCTGACCGCGGATCTCTGCGACCATCCGCACCGCCCGCTCACGCAGCTCCGGCGGGTACCTCCTCGATGAACCACCTGACATGACCCCATCCTTTCCAAGAACTGGAGTCTCCGGACATGCCGGGGCGGTTCACCGCGAGGTGGGTGTGTCGGTGTGACAGACGCCGTGTCGCGGTGGTTTGTTCCGGATCACCTGGTGTCTGGCTCACTTTGCGTCTGCCGTCCTCTTGGGGTTGGCGTTGAGCAGTATTGCCGGCACTAGGTGAGAAGGACCGGCCGGCGTGACTTGATAGGAGCGTGGCTTTCGCCCCGACTGAGATGTGTCCGCCGACCGGCCCAACCTCAACACCCCCTCAAGTGAAGGAGGCAACCACCATGGTTGTTGTTGGAACCGATGCGCACAAGTACAGCCACACCTTTGTGGCCACCGACGAAGTGGGTCGCCAACTCGGTGAGAAGACCGTCAAGGCCACCACGGCCGGGCACGCCACAGCCATCATGTGGGCCCGTGAACAGTTCGGCCTCGAGCTGATCTGAGGCATCGAGGACTGCCGCAACATGTCGGCGCGTCTGGAGCGTGACCTACTGGCGGCCGGCCAGCAGGTGGTGCGGGTACCCACCAAGCTGATGGCCCAGACCCGCAAGTCGGCGCGCAGTCGGGGCAAGTCGGATCCGATCGATGCGCTGGCGGTGGCGCGGGCGGTGCTGCGTGAAACCGACCTACCCCTGGCCACCCACGACGAGACGTCGCGGGAGTTGAAGTTGTTGACTGACCGTCGAGATGTCCTTGTGGCCCAACGCACGTCGGCGATCAACCGGTTGCGCTGGCTCGTCCATGAACTCGATCCCGAGCGGGCACCGGCAGCACGCTCGCTCGATGCCGCCAAGCACCAGCAGGCCCTGCGGACCTGGCTGGACACCCAGCCAGGATTGGTCGCCGAACTCGCGCGCGCCGAGCTGACCGACATCATCCGGCTCACCGGCGAGATCAACACCCTGGCCCAGCGCATCAGCGCCCGAGTCCACCAGGTCGCCCCCGCACTGCTGGAAATCCCTGGCTGCGCGGAGCTGACTGCAGCCAAAATCGTCGGCGAAGCCGCCGGAGTGACCCGGTTCAAAAGCGAAGCCGCCTTCGCCTGCCATGCCGCAGTGGCTCCCATCCCGGTGTGGTCGGGCAACACCGCCGGCCAGATGCGGCTCAGCCGCTCGGGCAACCGCCAGCTCAACGCCGCCCTACACCGCATCGCACTGACCCAAATCCGGATGACCGACAGCCGGGGCCAGGCCTACTACCAAAGGCTGCAAGACGCCGGGAAAACCAAACGCGCAGCACTACGCTGCCTCAAACGCCGCCTAGCCCGCACCGTCTTCCAGGCCCTGCGCACCGTCCACCAGCCCAGCTCCGAACACACCCAACCCGCGGCCGCTTGCCATAGGAGCTATTGCTCGTCACACCTCGGCGAGCCACCTCGTCTAACGGATATGACACAGAAAACCCGCATCCAGCCCCTACCTCCCAAGCGAGCCGGCCTGTTGATCCGCGCACTGTATCGGATCGCCAAGCGGCGCTTCGGCGAAGTTCCCGAGCCGTTCACGGTCACCGCACATCATCGGCGGCTGCTGATCGCCAATGTGGTGCACGAAGCCCTGCTGCAGCGAGCGTCGCGGAAGCTACCGCCCAGCGTCCGTGAGCTGGCGGTGTTTTGGACCGCCCGCAGCATCGGCTGCTCGTGGTGCGTGGACTTCGGAGCCATGCTGCAGCGCCTGGACGGGCTGGACGTGGACAGGCTCACGGACATCGACAATTACGCCACCTCATCGAAATTCAGCGACGACGAACGCGCCGCCATCGCCTACGCCGAGGCGATGACCGCAGACCCGCATTCGGTGACCGACGAGCAGGTGGCCGACCTGCGGGCCCGCTTCGGCGAGGCCGGCGTGATCGAGCTGACTTACCAGATCGGCGTGGAGAACATGCGAGCCCGGATGAATTCGGCGCTGGGCATCACCGAGCAAGGCTTCAATTCCGGTGATGCCTGCCGCGTCCCGTGGGCTGCGCCCGACGTTCCTTCAGCGGAGAGCCGGTGAACTTGTCGGGATTGGCGATATCCCACAGCGCGCACACCTTTCCGTCGCGCACGGTTATCGCGGTGATCCGCGGCGCCATCGCCCGATACCCGTCGACCCCGGGTAAGCCCGCCGTGTAGGCGCCGAGCTCTCCGTTGACCAGCGCCAGCTGATTCGCGCCGAAGAGCCCCGGGCCGTAACGCTGGACCAGCCCGAGTATGAACCGGACCACCTTGTCGGATCCGCGGACGGCCCGTACCGCTGTGGGCGCCTTGCCATTCGAATCGCCGGTAAACGTCACGTCGGGATGCAGCAGCGACACCACCGTGTCCAGGTCACCAGCGGCCATGGCGGCCATCAGCCGGCCGACCACCTCGTTGTGGGCCGGATCCGGATCCCCCGATATCAGGGCGGGCTGCGCCGTGACGGCCTTGCGGGCCCGCGACGCCAGCTGGCGCGCGGCGGCCTCGCTGGTTCCCAGCACCTCGGCCACTTCGGCAAACGGCACGGCGAACCCGTCGTGCAGCACGAACGCGACCCGCTGATCGGGGCGCAGCCGCTCCAGCACCACCATGGCCGCGAACCTGGCGTCCTCGGCGGCCACCACGGCGGCCAACGGATCGGTCGCGTCCAAGCCGGTGACCACCGGTTCGGGCAGCCAGGTGCCGGTGTAGGTCTCCCGCCGGTGCGCCGCCGACCTCAACTTGTCCAGACCCAGCCGGCTCACCACGGTGGTCAGCCAGGCCCGCGGGTCGGCGATCACGGTGTCCTGTGAGTCCCAGCGCAGCCAGGCCTCCTGCACGATGTCCTCAGCATCGGCGACCGTGCCGGTCAGCCTGTAGGCGACCGACATGAGATGCTGTCGCAGTGCCTCGAATTCGGAAACCTCCATCGAGGTCATTGCCCGAGCCTAGCGCTGCGCTCGCCAACACGACGACACGAAACCTTTGGTTGCACTTCGCCCGGCACGGTGCCGGCATCCAACACCCGGTCATCGTCCGCGGCGACGGCGTCACCATCTTCGACGACCGCGGCAAGAGCTATCTGGACGCCTTGTCCGGGCTGTTCGTGGTGCAGGTCGGTTACGGCCGGGCCGAACTCGCCGAGGCGGCCGCGCGGCAAGCCGGCACGCTGGGGTATTTCCCGCTCTGGGGGTATGCCACCCCGCCGGCGATCGAGCTCGCCGAGCGCCTGGCCCGCTACGCGCCCGGGGACCTAAACCGGGTGTTTTTCACCAGCGGCGGCACCGAGGCCGTCGAAACCGCCTGGAAGGTGGCCAAGCAGTACTTCAAGCTCACCGGCAAACCGGGCAAACACAAGGTCATTTCACGCTCGATCGCCTACCACGGCACCACCCAGGGCGCGCTGGCGATCACCGGCCTGCCATTGTTCAAGGCGCCATTCGAACCGCTGACGCCGGGCGGCTTCCGGGTGCCCAACACCAATTTCTACCGAGCACCGTTGCACACCGACCTCAAAGAGTTCGGGCGATGGGCTGCTGACCGGATCGCCGAGGCCATCGAGTTCGAAGGCCCCGACACCGTGGCCGCGGTGTTTTTGGAGCCGGTGCAGAACGCGGGCGGCTGCATCCCGGCGCCGCCGGGTTATTTCGAACGGGTCCGCGAGATCTGTGACCGCTACGACGTGCTGCTGGTCTCCGACGAGGTGATCTGTGCGTTCGGCCGGATCGGGTCGATGTTCGCCTGTGAAGACCTCGGCTACGTGCCCGACATGATCACCTGCGCCAAGGGCCTGACGTCGGGCTACTCGCCGCTGGGCGCGATGATCGCCAGCGACCGGTTGTTCGAACCGTTCAACGACGGCGAGACGATGTTCGCACACGGCTACACGTTTGGCGGTCATCCGGTGTCGGCGGCCGTCGGCCTGGCCAACCTCGACATCTTCGAGCGCGAGGGTCTCAGCGATCACGTCAAGCGGAATTCCCCCGCGCTGCGGGCCACCCTGGAGAAACTGTACGACCTGCCCATCGTCGGCGACATCCGCGGCGAGGGGTATTTCTTCGGCATCGAACTGGTCAAAGACCAGGCGACCAAGCAAACCTTCACCGATGACGAACGCGCACGACTGCTAGGCCAGGTATCCGCGGCGCTCTTTGAGGCCGGGCTGTACTGCCGCACCGACGACCGCGGGGACCCCGTCGTCCAGGTGGCTCCCCCGCTGATTAGCGGACAGCCCGAGTTCGACACCATCGAAACCATCCTGCGCAGCGTGCTCACCGACACCGGACGCAAATATCTTCATCTGTAACTTTCGTCCCGCCAGTCACAGCGCGGCTCCTCGCGGTCGGGCCGCCGATCACCTACTCTGCACAGACGATGGCCTTCTTACGTTCGGTATCGTGCCTGGCAGCAGCCGTGTTTGCGGTAGGCACCGGAATTGGTCTACCTACCGCGGCCGGCGAACCCAATGCCGCACCGGCGGCGTGCCCGTACAAGGTGTCCACCCCACCCGCCGTGGACTCGTCGGAGGTTCCCGCGGCCGGTGAACCCCCACTGCCGCTGGTGGTACCCCCCACCCCGGTCGGCGGCAACGCGCTGGGCGGCTGCGGCATCATCACCGCCCCTGGCAGCGCGCCAGCGCCCGGCGACGTCTCAGCCGAGGCCTGGCTGGTGGCGGACCTGGACAGCGGCGCGGTGATCGCCGCCCGGGATCCGCACGGCCGGCACCGCCCGGCCAGCGTCATCAAGGTGCTGGTGGCGATGGCGTCCATCAACACGCTCACCCTCAACAAGTCGGTCGCCGGAACCGCCGACGACGCGGCGGTCGAGGGCACCAAAGTCGGGGTGAACACCGGTGGCACCTACACCGTCAACCAGCTGCTGCACGGGCTGCTGATGCACTCCGGCAACGACGCTGCGTACGCGCTGGCCAGGCAGCTCGGCGGCATGCCGGCCGCGCTGGAGAAAATCAATCTGCTGGCCGCCAAGCTGGGCGGCCGGGACACCCGAGTGGCCACGCCGTCCGGACTGGACGGGCCCGGCATGAGCACGTCGGCCTATGACATCGGCCTGTTCTACCGGTACGCGTGGCAGAACCCGGTCTTCGCCGACATCGTCGCGACCCGCACCTTCGACTTCCCGGGGCACGGCGACCATCCAGGCTACGAGTTGGAGAACGACAACCAGCTGCTCTACAACTATCCGGGCGCGCTCGGCGGCAAGACCGGCTATACCGACGACGCGGGGCAGACCTTCGTGGGCGCGGCCAACCGCGACGGCCGGCGGCTGATGACGGTGCTGCTGCACGGGACCCGGCAGCCGATCCCGCCGTGGGAGCAGGCGGCGCACCTGCTCGACTACGGGTTCAACACCCCGGCAGGCACCCAGATCGGGACACTGATCGAACCCGACCCGTCGCTGATGTCCACCGACCGCAATCCCGCCGACCGGCAACGAGTCGACCCCCAGGCCGCGGCGCGGATATCGGCCGCCGACGCCCTTCCGGTGCGGGTTGGCGTGGCCGTCATCGGCGCCCTGATCGTGTTCGGGTTGATCATGGTCGCGCGGGCGATGAACCGCCGGCCGCAGCACTAGCTGCTTACCCCGATACCTTCGGCGTCGTTTGCGGGCGGGCATCCTAGCCGGCCTTGGTCGGCACCGAAATCGGGGCTTGACCAGCGGTTGACCGCGTGACGACGCTGTGGCAGCCTCATCGAAATGACTACAGCCCTATACCAGGACGCGGGGTTCACGCCCGCCGGGGCGCCCGACGACCCCGACCGCGTGGTGGACGTGCTGAGCGCCCCGGTACCGGTCAACTGACCAGATCGGGGCGCCGGGCGCTCCTCGTCGGGCTCACCGCCGCCAGCGTCGGCGTCCTCTACGGGTACGACCTTTCCGCCATCGCGGGTGCGTTGCTGTCTCTCAGCGAGGAATTCGAACTCACCACTCGAGAACAGGAGTTGCTGACCACCACGGCGGTGCTCGGCCAGATCGCCGGGGCGCTTGGCGGCGGCATCCTCGCCAACGCGATCGGACGCAAGAAATCGGTGGTGCTCATCGTCGCCGGCTACGCAGTGTTCGCCCTGCTCGGCGCGACCTCGGTGTCCGTACCGATGCTGGTGGTGGCGCGTCTGCTGCTGGGTGTGACAATCGGCCTGTCGGTGGTGGTGGTGCCGGTGTATGTGGCCGAGTCGGCGCCGGCGGCGGTGCGTGGGTCGTTGGTGACCGCGTATCAGCTGGCGACGCTTAGCGGCATCGTCGTCGGTTACCTGGTCGGCTACCTGTTGGCCGGATCGCACGGCTGGCGCGCGATGTTCGGGCTGGCCGCCGCGCCGGCCACGCTGCTGTTGCCGTTGTTGTGGCGCATGCCCGATACCGCCCGCTGGTATCTGCTCAAGGGCCGGATCGCCGACGCGCGTAGCGCGCTGCGGCGGATCCAGCCGGAGGCCGACATCGATGCCGAGCTGGCCGATATGGCGGCCGCGGTCGACGAACGCGGCGGCGGTATCGGCGAAATGGTGCGGCGGCCGTATCTGCGGGCCACGCTGTTCGTCATCGCGCTCGGCTTCCTCGTCCAGATCACCGGGATCAACGCGATCATCTACTACAGTCCGCGACTTTTCGCCGCCATGGGCTTCGCGGGCTATTTCGCGATGCTTGCCCTGCCCGCGATGGTGCAAGTCGCCGGCTTGGCGGCGGTGTGTGCCTCGCTGTTTCTGGTCGATCGGCTGGGCCGTCGCCCGATCCTGTTGTCCGGCATCGCGACGATGATCACCGCAGATGCCGTGCTGATCACCGTATTCGCCAACGACTCCGATGGTGGCACGGGGCTGGTGTTGGGGTTCGCCGGCGTGCTGCTGTTCATCATCGGGTTCAACTTCGGATTCGGCTCGCTGGTCTGGGTGTACGCCGCGGAGAGCTTCCCGTCCCGGCTGCGGTCGATGGGATCGAGCCTGATGCTCACCTCGACACTGACGGCCAACGCGATCGTTGCCGCCTTCTCGCTCACCATGCTGCGTGTGCTCGGCGGCGCAGGCGTTTTCGCGGTCTTCGGCACGTTCGCCGTCGTCGCGTTCGTGGTCGTGTACCGCTTTGCGCCGGAGACCAAGGGCCGCAAACTCGAGGAGATCCGGCACTTCTGGGAGAACGGCGGCCGCTGGCCCGCCGAGCGGTCACCGGCGGCGGACGAACCGTGACCGTGCTCGGCGCCGACGCCGTCGTCATCGACGGCCGGATATGCCGGCCAGGGTGGGTGCACACCGCCGATGGTCGGATTCTCTCCGGTGGCGCTGGGGCACCGCCCATGCCGGCCGACGCGGAATTCCCCGATGCGATCGTGGTGCCCGGCTTTGTCGATATGCATGTGCACGGCGGGGGCGGCGCGTCGTTCGCCGACGGCAACGCCGCAGACATCGCCCGTGCGGCCGAGTTTCACCTGCGGCACGGCACCACTACCACGCTGGCCAGTCTGGTCACCGCGGGCCCCGCCGAGTTGCTCTCCGCCGTGGGCGCTTTGGCCGAGGCAACTCGGGACGGCGTCGTCGCGGGCATCCATCTGGAGGGGCCGTGGCTGAGCCCAGCGCGGTGCGGAGCGCACGACCACACCCGGATGCGTGCCCCGGATCCCGCCGAGATCGAGTCGGTGCTCGCCGCCGCCGACGGCGCCGTCCGGATGGTCACGTTGGCACCCGAGTTGCCCGGAAGCGATGCGGCGATCCGGCGCTTCCGTGACGCCGAAGTGGTTGTCGCCGTGGGGCATACGGATGCGACCTACACACAGACCCGACACGCCATCGACCTGGGCGCGACAGTCGGCACCCACCTGTTCAACGCGATGCCGCCGCTGGACCATCGGGCGCCCGGACCCGTGCTGGCGTTGCTGTGCGACCCGCGGGTGACCGTCGAAATCATCGCCGACGGCGTGCACGTGCACCCCGCGGTGGTGCACGCGGTGATCGAAGCCGTCGGTCCCGATCGGGTCGCCGTGGTCACCGACGCGATCGCCGCGGCCGGATGCGGCGATGGCGCGTTCCGGCTCGGCACAATGCCGATCGAGGTCGAGTCGAGCGTGGCACGGGTGGCTGGTGCGTCGACGCTGGCGGGCAGCACCACCACCATGGATCAGCTCTTCCGGACGGTGGCTGGGCTCGGCTCGAAGTCGGACTCAGCCGGCGATGTGGCGCTGGCCGCCGCGGTGCAGGTGACCTCGGCGACGCCGGCCCGCGCTCTCGGGCTCACCGGGGTGGGCCGGCTGGCGGCGGGCTATGCCGCCAATCTTGTTGTGCTGGACCGTGATCTGCGGGTGACGGCCGTCATGGTCAACGATGACTGGCGGGTGGGCTGAGCGTCCGTGGAGGCCCGTCACAATGCCCAGGCTCGCACCGTGAGTACTCGGTCAACGTTGACGGTTGCCCCGGCGACCCGGTCACTCTGGCGAGGGCTACCGGCGCCGCGCGGCTTGTACCGCAATCATCCGATCGCCGCGAAGCGCTCGGCAGCCGGCTTGGGCGGTAGCCGACGACACGGGTACGGTCTCACGGCGCGAGCCTGATAAAGCCCGGCGGCATGGGTCGTGCAGGCGACGGCTCTACCGGTCCGTCACCACCGCCGCCACCACCGCTGCCGGCGCCGCCACTGCCGGCAGCGCCCCCGGACTGCGGAACACCAGCAGGCGGCTCAACCTCTGGCGGCGGGGGCGGCGGCTGTTGCGGCGGCGCTGGTCGCGGTGGCGGCGGTGCCACGATCGGCGGGGGTGGAATCAGGGTCTGCGCCGCCGGCGGCGGTACCGGAATCGGCGGCGGATTCGGTATCAGGGGATCCCCCGCGCGAACCGCTCCGAGCACCGAGGCAAGCATCGCACCCGTCGGTTCCCGCCATCCCGGCGACATGATGGTCATGTCCGACACCGACGCCCGCAGGTCGCTTCCCGAGTTGACCGCGCTGCGCGTGGACGCCGCAACGCGATGCGTCGGTTCATTCGATCCCGGCTCGAAATTGGCCATGGCGAACGCCATCTTGCTGTGATGGTTCGGGCAGTAGATCTCCACTGCCGCACTGATAAATCGGGTCATGGTCGTCGTGAGGCGGACAGGGTAGAGGCGCATGACCGGGTCTATGTTGTAGGCATCGTTGCGTAACCCGTCCACAATGTCGTTCACCGGCATGCCGCCATCGAGTTTGCGACACACTTTGTGGGCCGCGTCGATGACGCGAGGCACATTCGCGACGGCGGGGATTTCCTTTTTCTCGAGCAGCGCCAGAAACCGATCGTCTTGGTTTGGGTCGGCCGCTGCTGGGCCGTCGTGCAGAATTGCGGCGCCGATCAGCACCACTAAGGCGGCACCCAGGGCGCCGGCATGGCTAGCGATGCCGGTGAACATGATGGGGTTTCCGTTCTGCTAAAAGCCGTTACCTGGCGGGCTTTGGATCGCGATCCACGCCATAGGTGTGGCTGTCTGGTCAGGTTTGACCGGCGCCATGATGTCGTTTCACAGCGCCGATGCAGTCTGGGAGGGGACCAGGGCATGGGTGCATTGAGGAGCCAGATCCAGAGAACCACACCGGAGCCGCTGGCCGAGGCTCATCCACAAGCCTTCGATCCCGCTCCCGTTGTCGGCATGGGCGCCTGCCGACGGAATCAGCGGATGGTCATAGTGGCGTCGGGCGCCAGGCCTGCGCGGGCACACGCGGTGCGGTGTCGATGGTTGTTCTCATCTGGTAACTCCTTTCCGCAGGCCGCAATTCAGCGGTATGGGCTCACCGAGATCAGGCTCGTCACGATCGCCCGCACTGCTGGCGGCTCACATGTACCCAGTGTTAACCTTCTAGTGCACTAGAAGGTCAAGGGGAGTCGCATGAAGATCAGCGAGGTAGCCGCGCTCACCAACACCAGCACCAAGACCCTCCGCTTCTACGAGAACTCGGGGCTGCTGCCGCCGCCTGCACGCACAGCATCGGGGTATCGCAACTATGGACCCGAGATCGTGGATCGGCTGCGGTTTATCCATCGGGGCCAAGCGGCCGGGCTGGCATTACAGGAAGTACGCCAAATCCTGGCCATCCACGACCGCGGCGAGGCGCCGTGCGCACACGTCCGCCAACTACTGAGCACCCGCATCGACGAAGTCCGCGCGCAGATCGCCGAACTGATTGCCCTCGAAGGCCACTTGCAGACCCTGCTTGACCACGCTTCATATGGCCCGCCCACCGAACACGACCACTCCACGGTGTGTTGGATCCTGGAAAGCGACCTCGATGAGCCCACCGCCATCGAGGTCAGCGACATTCACGCCTAGAGGTCGCTGGGTACGCGGGCTGGCCCACGGGTTTTACGCCGAAGCCGTCGCCGCCCACGCGGTGGCGAACAGGATCAGCCACGCGGTGACGAACGCGAACACCATCAACCCCAGCACCGGCCCGAACACCGCGCCCGCCGGGCTGCGCAACACTATCTGCAGGTAGATCGCCCCCACCTGCTTGAACAGCTCGAAGCCGACCGCCGCCATCAACCCGGCCCGCGCCGCGGTGACCAAACCGACCGGCTCCCGCGGCAGCCGGCCAATCATCCAGGTGAACAGCACCCACGACACCAGCACCGATACCAGCACCGAGATGCCCCGAAAGATCTCGTCGAACACTGAAAACTGGGGTATTTCAAGCCATCTCAGTACCGCAGCCATCGGCCTGGCATGGCCGAGCACGGTGAGCGCGATGGTGGCCACGATCACCACGAACGTCCCCACCATGGCCGCTAGATCCGACAGTTTGGTGCGCAAGTAGCCCGCCGGAGCGACTGGATGTGCCCACATCTGGCTCAACGCTTCCCGCAGGTGCCACATCCAGCCCAGGCCCACCCAGGCCGCGGTCGCCAGACCGATCACCCCGACCGACGCGCGTGCATCGATCGCCGAATTCATCAGGTCGACCAGCTGCTGTCCCACCGCACCGGAGACCGAGGTGCGGATGCGCTCCTCGAGCGTGGTCAGCAGCTCCGGACGACGCGACAACGCGAATCCACCCACCCCGAAACCGACCATCAGCAAAGGAAATATCGCAAAGATCGTGTAGTAGGTGAGTCCGGCCGCAAAAAGACTGCCGTTGCGATCGTTAAAGCGCGTGAACGCACGCACGACATGGTCCAACCACCCGAACCGGGCCCGCAGCCGGTCAAGCACCCCTGGCTCGGCGAGCTCGCCCATGATCGACTGCCCTACCCCCGTTATAGAAGGAACCCGAGCCGATCGTAGACTCGCTGAACCGTTTTGCTGGCCACATCGTGGGCGCGCTGCGCCCCGGCGGCGAGCACGGCCTCCAGCTCCGCGGGATCTGCGGTCAATTCGTCAACTCTGGCTTGGATCGGGTTGACGAATTCGACGACGGCCTCGGCGGTGTCTTTCTTCAAATCGCCGTAGCCGTGTCCGGCATAGCCGTCGACGAGAACGTCGATGTCGGTCCCGGTGACCGCCGACTGGATGTTCAACAGGTTAGACACCCCTGGCTTGACGTCCGGGTCATAGCGGATGTCACGTTCGCTGTCGGTCACGGCGGAGCGAATCTTCTTGGCGGACAATGCCGGATCGTCGAGCAGGTTGATCAAACCGGCATCGGTGCCCGCCGATTTGCTCATCTTTGACGTCGGGTCTTGTAGATCGTAGATTTTGGCGGTCATCTTGGGGATGAGCACGTCGGGAACCACCAGGGTGCCGGGGAATCGGCTGTTGAACCGTTGCGCGACGTCGCGGGCCAGCTCGAGGTGCTGCCGCTGATCCTCCCCGACGGGCACCAGCTCGGTGTCGTAGGCCAACACGTCCGCGGCCTGCAGTACCGGGTAGGTGAACAGGCCGACGGTGGTGGCCTCGCTGCCCTGACGCGCCGACTTGTCTTTGAACTGGGTCATCCGCGACGCCTGGCCAAAGCCGGTGAAACAACCCAGCACCCACGCCAGCTGGGTGTGAGCCGGCACCTGACTTTGCACGAAGATGGTGGCGCGGCCGGGATCGATTCCCAACGCCAGGTATTGCGCGGCGGTAATCAGGGTCCGGCGCCGCAGTGCCTCGGGATCCTGAGGGATGGTGATCGCATGCAGGTCGACCACGCAGAAGAACGCATCGTGGTCATCCTGCAAGCCAACCCATTGGGCGACGGCGCCCAAGGCATTACCGAGGTGAAGCGAGTCAGACGTGGGCTGCACGCCGGAGAAGATCCGGCGGGACCCGGTAGGGGTGCTCATGATGCCCCGATCCTTTCACGCGGGGTGCCCTCCCCGTCGACCACCGGTCACCACGCTGCTTGCGGTACCGGCGGTACCGGCTTTAGTGTCGGCTCTATGCGCAGTCCGATACGCGTGGGTTCGGGAGAGCCGGTCCTACTGCTACACCCGTTCTTGATGTCCCAAACGGTGTGGGAGAAGGTCGCCCAGCAGCTGGCCGACACCGGCCGCTTCGAGGTATTTGCCCCCACGATGGCCGGCCACAACGGCGGACCGGCCTCGGGCACCCGGTTTTGTCCTCGGCGGTGCTGGCCGACCACGTCGAACGCCAGCTCGACGAACTGGGCTGGGAAACCAGCCATATCGTCGGCAACTCGTTGGGCGGCTGGGTCGCGTTCGAACTCGAACGACGTGGCCGGGCACGCAGCGTGACCGGTATCGCCCCGGCGGGCGGTTGGACCCGCTGGAGTCCGGTCAAGTTCGAAGTGATCGCTAAGTTCATCGCAGGGGCGCCGATCTTGGCCGTCGCCCACATTCTTGGCCAACGGGCGCTTCGGCTGCCGTTCAGCCGCCTGCTGGCCACCCTGCCGATCAGCGCCACACCGGACGGCGTGAGCGAGCGCGAGCTGTCCGGCATCATCGACGACGCCGCGCACTGCCCGGCCTATTTTCAGCTGCTGGTCAAGGCGCTGGTGCTGCCCGGGCTGCAGGAGTTGGAACACACCGCCGTGCCCTCGCACGTGGTGCTGTGCGAGCAGGACCGGGTGGTCCCTCCCAGCAGGTTCAGCCGTCATTTCACCGACTCACTGCCGGCGGGCCACCGGCTCACCGTGCTCGACGGCGTCGGTCACGTTCCGATGTTCGAGGCTCCGGGGCGCATCACTGAGCTGATCACCAGCTTCATCGAAGAGTGCTGCCCGCATGTCCGGGCCAGTTAGCGGGCGCGAGCAGACGCAAAATCGCCCATTTCGGCACGAAATTGGGCGATTTTGCGTCTGCTCGCCCTAATTGGCCAGCTCCTTTTCCAGGTTGTCGGCGATCGCATCGAGGAATTCCTCGCTATTCAGCCAGTCCTGCTCCGGACCGATGAGGATCGCGAGGTCCTTGGTCATCTTCCCGCTCTCCACCGTGGCGATGACGACGGACTCCAGCTTGTGGGCGAAGTCGATGACTTCGGGAGTGCCATCCAGCTTGCCGCGATGCTGTAATCCGCGGGTCCAGGCAAAGATCGACGCGATCGGGTTTGTTGAGGTCGGTTTACCGGCCTGATACTGCCGGTAATGCCGGGTGACGGTGCCGTGGGCGGCTTCGGCCTCGACTGTCTTGCCGTCGGCCGTCATCAGCACCGACGTCATCAGGCCCAGCGAGCCGTAGCCCTGTGCGACGGTGTCCGACTGCACGTCGCCGTCGTAGTTCTTGCACGCCCAGACGTAACCGCCTTCCCATTTCAGGCAGGCGGCGACCATGTCGTCGATCAACCGATGCTCGTAGGTCAGCCCCGCCGCTTCGAACTGCGCCTTGAATTCCTCTTCGTAGACGCGCTCGAACTCGTCTTTGAACATCCCGTCGTAGGCCTTGAGGATGGTGTTCTTGGTGGACAGATATACCGGCCATTTCGCGTTGAGGCCGTAGGAGAACGACGCGCGCGCGAAATCCCGGATGGATTCCTTGAAGTTGTACATCCCCAGCACGACGCCGCCGTCCTCGGGGATGGACACCATTTCGTGCACGATCGGCGCGCTGCCGTCGGCGGGCGTGAAAGTCAGTGTGACGGTGCCCGGTTGGTCGACCTTGAAGTTCGTCGCCCGATATTGGTCACCAAAAGCGTGCCGGCCGATGACGATCGGCTTGGTCCACCCCGGAACCAGTCGCGGCACATTAGAAATCACGATAGGTTCGCGAAAGATTGTGCCGCCCAAGATGTTCCGGATTGTCCCATTGGGCGACAGCCACATCTTCTTCAGGTTGAATTCCTCGACACGGGCCTCGTCGGGGGTGATCGTCGCGCACTTTACGCCCACACCGTGTTTCTTGATCGCATACGCCGCGTCGATCGTCACCTGGTCGTCGGTGGCGTCGCGGTGCTCGATGCCCAAGTCGTAATAGTCCAAGCGGATGTCGAGATAGGGAAGGATAAGCATGTCCTTGATGAGCTTCCAGATGACACGGGTCATCTCGTCACCGTCGAGCTCTACGACCGGACCGCTGACTTTTATCTTGGGTGCGTTGGACATGGGAGTCCACATCAGATTACTAGCAGCCCGCGCGGGCCCCTAGCGGCCGGTAAAGGGCCAGTTGAGACCGCCGGAGTTGTGCTTTGAGTTGGCACTGAGTAGCTGCCATGCGCTAGGCTTCGAGTCGGTCATGAGCGCCAGCGTCAAGCCCCGGCTTGCTGGCCGGCAACCCTCCAACCGCGGTGGGGTGCCCCGGGTGATGACCAGGTTGAGTAGCCATCGCCGGCTGCGCGGCAAGCGCGGGTCCGCCATGACGGGCCCCTGACCAGACGGGGAAAGCTCATGAGCGCCGACAGCAATAGCACCGACGCCGATCCGACCGCGCATTGGTCGTTCGAAACCAAACAGATACACGCTGGTCAGCACCCTGATCCGACCACCAACGCCCGGGCTCTGCCGATCTATGCGACCACGTCGTACACCTTCGACGACACCGCGCACGCCGCCGCCCTGTTCGGACTGGAAATTCCGGGCAATATCTACACCCGGATCGGCAACCCCACCACCGACGTCGTCGAGCAGCGCATCGCCGCGCTCGAGGGCGGTGTGGCCGCGCTGTTCCTGTCGTCGGGGCAGGCCGCGGAGACGTTCGCCATCTTGAACCTGGCCGGCGCGGGCGATCACATCGTGTCCAGCCCGCGCCTGTACGGCGGCACCTACAACCTGTTCCACTATTCGCTGGCCAAGCTCGGCATCGAGGTCAGCTTCGTCGACGATCCGGACGATCTGGACACCTGGCAGGCGGCGGTACGGCCCAACACCAAGGCGTTCTTCGCCGAGACCATCTCCAACCCGCAGATCGACCTGCTGGACACCCCGGCGGTTTCCGAGGTCGCCCATCGCAACGGGGTGCCGTTGATCGTCGACAACACCATCGCCACGCCATACCTGATCCAACCGTTGGCCCAGGGCGCCGACATCGTCGTGCATTCGGCCACCAAGTACCTGGGCGGGCACGGTGCCGCCATCGCGGGTGTGATCGTCGACGGCGGCAACTTCGATTGGACCCAGGGCCGCTTCCCCGGCTTCACCACCCCCGACCCCAGCTACCACGGCGTGGTGTTCGCCGAGCTGGGTCCACCGGCGTTTGCGCTCAAAGCTCGAGTGCAGCTGCTCCGTGACTACGGCTCGGCGGCTTCGCCGTTCAACGCGTTCTTGGTGGCGCAGGGTCTGGAAACGCTGAGCCTGCGGATCGAGCGGCACGTCGCCAACGCGCAGCGCGTCGCCGAGTTCCTGGCCGCCCGCGACGACGTGCTTTCGGTCAACTATGCGGGGCTGCCCTCCTCGCCCTGGCATGAGCGGGCCAAGAGGCTGGCGCCCAAGGGAACCGGGGCCGTGCTGTCCTTCGAGTTGGCCGGCGGCATCGAGGCCGGCAAGGCATTCGTGAACGCGTTGAAGCTGCACAGCCACGTCGCCAACATCGGTGACGTGCGCTCGCTGGTGATCCACCCGGCATCGACCACTCATGCCCAGCTGAGCCCGGCCGAGCAGCTGGCGACCGGGGTCAGCCCGGGCCTGGTGCGTTTGGCTGTGGGCATCGAAGGTATCGACGATATCCTGGCCGACCTGGAGCTTGGCTTTGCCGCGGCCCGCAGATTCAGCGCCGACCCGCAGTCCGTGGCGGCGTTCTGAGGAATTCTGACATGACGATCTCCGATGTACCCACCCAGACGCTGCCCGCCGAAGGCGAAATCGGCCTGATAGACGTCGGCTCGCTGCAACTGGAAAGCGGGGCGGTGATCGACGATGTCTGTATCGCCGTGCAACGCTGGGGCAAATTGTCGCCCGCACGGGACAACGTGGTGGTGGTCTTGCACGCGCTCACCGGCGACTCGCACATCACTGGACCCGCCGGACCCGGCCACCCCACCCCCGGCTGGTGGGACGGGGTGGCCGGGCCGGGTGCGCCGATTGACACCACCCGCTGGTGCGCGGTAGCTACCAATGTGCTCGGCGGCTGCCGCGGCTCCACCGGGCCCAGCTCGCTTGCCCGCGACGGAAAGCCTTGGGGCTCAAGATTTCCGCTGATCTCGATACGTGACCAGGTGCAGGCGGACGTCGCGGCGCTGGCCGCGCTGGGCATCACCGAGGTCGCCGCCGTCGTCGGCGGCTCCATGGGCGGCGCCCGGGCCCTGGAATGGGTGGTCGGCTACCCGGATCGGGTCCGAGCCGGATTGCTGCTGGCGGTCGGTGCGCGTGCCACCGCAGACCAGATCGGCACGCAGACAACGCAAATCGCGGCCATCAAAGCCGACCCGGACTGGCAGAGCGGCGACTACCACGAGACGGGGAGGGCACCAGACGCCGGGCTGCGACTCGCCCGCCGCTTCGCGCACCTCACCTACCGCGGCGAGATCGAGCTCGACACCCGGTTCGCCAACCACAACCAGGGCAACGAGGATCCGACGGCCGGCGGGCGCTACGCGGTGCAAAGTTATCTGGAACACCAAGGAGACAAACTGTTATCCCGGTTCGACGCCGGCAGCTACGTGATTCTCACCGAGGCGCTCAACAGCCACGACGTCGGCCGCGGCCGCGGCGGGGTCTCCGCGGCTCTGCGCGCCTGCCCGGTGCCGGTGGTGGTGGGCGGCATCACCTCCGACCGGCTCTACCCGCTGCGCCTGCAGCAGGAGCTGGCCGACCTGCTGCCGGGCTGCGCCGGGCTGCGAGTCGTCGAGTCGGTCTACGGACACGACGGCTTCCTGGTGGAAACCGAGGCCGTGGGCGAATTGATCCGCCAGACACTGGGATTGGCTGATCGTGAAGGCGCGTGTCGGCGGTGACGTGCTCCCGACGCGACATGTCCCTGTCGTTTGGCTCCGCGGTCGGCGCCTACGAGCGCGGGCGCCCCTCGTATCCACCGGAAGCCATCGACTGGCTGCTGCCGGCCGCCGCCCGCCGCGTGCTCGACCTGGGAGCGGGCACCGGCAAGCTGACCACCCGGCTAGTCGAGCGCGGCCTGGACGTGGTTGCCGTCGACCCGATCCCGGAGATGCTGGACGTGCTGCGTGCTGCGCTGCCGCAAACCGTCGCGCTGCTGGGCACCGCCGAAGAGATTCCGTTGGACGACAACAGCGTTGACGCGGTGTTGGTGGCTCAGGCGTGGCACTGGGTGGATCCCGCCCGGGCGATTCCGGAGGTCGCCCGGGTGTTGCGTCCGGGCGGGCGGCTCGGCCTGGTGTGGAACACCCGCGACGAACGGCTGGGCTGGGTGCGCGAGCTGGGTGAGATCATCGGTCGCGACGGCGATCCGGTGCGCGACAGGGTGACGCTGCCCGAGCCGTTCACTACGGTGCAGCGCCATCAGGTCGAGTGGACGAATTACCTGACACCACAAGCCCTTATCGACCTGGTGGCTTCGCGCAGCTATTGCATCACCTCACCGGCGCAGGTCCGCACCAAAACGCTCGACCGGGTGCGGCAGTTGCTGGCCACCCATCCGGCGCTGGCGAATAGCAACGGCCTGGCGCTGCCCTACGTCACGGTCTGTGTGCGGGCGACTCTGGCCTGACGCCGCCTTTAGGGCCCGGTGCCGGTGTAAATCAGGCCCGCCAGTTGCTGGCCGACGTTGCCGAAGCCGGAGACCAGGGCCGAGGTGATCAGGCCCAGCGCGCCGGTGTTGTACACACCCGAGATGTCCGCGCCGCGGTTGAGGATGCCGGAGAGTTGGGTGCCGAAGTTGGCGAAGCCCGACGCCGATCCGAGCAGCGGATCCGAGATCGCGTTGAGCACGCCCGACATGCCCGCGCCGAGGTTGTGGAAGCCCGACAACCCGCCGCCACCGCCGATGTTGAAGAACCCCGACGACGGGACCGCGGTGGTGTTGCCGAATCCCGGGACGGGCGGGATGACCAACCCGGCGTTGATGGGGCCGAGCAGCGCGTTGACGTCGAGAACCACTGGGATTCGGTCGATGGTGATCTCCAGAGGGAAGGCGAAGGCGGGGGTGGCGCCGGACAACGCGAGGCCCAGCGGGAGTTGGGGAATGGTGATTTCCGGGCTCACGAAGGGTCCGATGGTGACGGACAGGGGCAGCTCGACATGGATTGGATCGACGGGTATGTGGAATCCCGGGATGGTGATTTCCGGTGTTAGATGGGTCACGCCAAGCGAACTCAGCAGCACGGTGAATGGCAGAATCTCGCTGGGCGCCGTTTGGATGGCGGGGACATTAACGTTGATGAACCCCAGCAGCGTAAGGCTGAATGGATCGATGATGGAGCCTGAGCTGAATATCGGGCCCACGGTGACACCGGTTGCGGGGTCGAGTCCCAGGGCGGGAATCGTGATGTCCTGGACGGTGATGGGGCCGAGGTCGAAGACTGGGTCGATGCGAACCGTGATCGGGGAAATGGACACCGGCGGGATGGTGAAGCCGCCGATGTGGCCGGTTGCGCTGAGGTCCAAGGGAATTGCCGGAAATTGGATCGACGGAACGATGATGGGTCCGGCGCCGCCGGACGCGTGGATGTTCGCGACAGTGAATTCGGGAATGATGGTGCTGGTGTAGGAGAAGCCGAGCAGGCCCTGGTAGTCGCCCCGCCAGAAGGCGCCGTTGCTGTAGTTGCCGGAGATGAAGGCGCCGGTGTTGACGTCGCCGGAGTTGGCCACCCCGGTGTTGGTGTCACCGGTGTTCAACCAACCCGTGTTGACACTGCCCGGGTTGAAACCGCCGGTATTGGCCTGCCCCGCGTTGAAACTGCCGGTGTTGTAGCTACCCGCATTGACCACACCCGTGTTGAACCCACCCGCGTTGAACAACCCCGTGCTGACAATCCCCGAATTACCGATCCCGGTATTATAACTCCCCGAATTGAACACCCCCCAGTTCCCGGTGCCAGAGTTAAAGAACCCCACATTACCGGTCCCCGAATTAAACAACCCCACATTCCCGCTGCCGGTATTGAAACCACCGAACCCGGTCAGATTATCACCGGTCAACCCAATACCGAAATTCCCACTGCCGGTGTTAGCGAACCCAATATTGCCCACACCCATATTCGCCAAACCGAAATTGTAGCTGCCGGCATTACCAAACCCGATATTACCCAAACCCATCAGACCCGGCGTTAACCCCGAATTCCCGAGCCCAAAGTTGCCCCACCCGACATTGCCCAACCCGACATTGTTGCCGCCGATATTGCCGCCGCCCACATTGAACCCACCGACGTTGCCCGCACCCAGGTTAAAGTCCCCGACATTGCCCAACCCGACATTGCCCAACCCCACATCGGCCAACCCGAAATTGAGGACCAGACCCTGATGCAGCGCCGTCCCGCTCGCCAACAATCCCGACAACTGCTGACCGACACTACCCAAACCCGACACCAACGCCGGCGCACCCAACCCCAACACGCTGGTGTTGAACAGCCCCGACATGCCAGAGCCGAAATTCAGCACACCCGAATGCAGCGTGCCGGCGTTGAAAACACCCGAACCCCCACCCAGCAACGCCGACGGAGCCTGATTCCAGCCACCCGACACCATCGCGCCGACATTCCCAAACCCCGACACCCCACCCGCACCGGAGTTGAAGAAACCCGACGACGGAGCACCGGTCGTATTCCCGAACCCCGGCACGGCGGGAAGGTCGATGAGGATGTGAACGGGGCCGAGCGTGCTGTGGGCCACGAGGTCAAAGGGGATTTCGCCGATGGTGATTGCCGGAATGGTGACGGCGCCGGTGCCACCGGACAGGTTGATGCTCAGCGGGTTCATCGCGGGGATCGTGAGGCCGCCCGGGAAGATGTCGACGGGCTCGCTGTGGCCGGTAATGCTGGCCAGCAGCGGGATCTCGTCAATGGTGACGACGGGGGTGCTGAACGGCAGGTTGGCCAGGAAAGCCGTGATGGTCCCTTGCGACGAGCTAGCACCGATGACTATCTGGCTTAACGCCAGGGGGGTAAGGCCGATGGGGGTGTTGAAGAGTCCCGTAATCGGACCGATTTTCAGGGGCCCGCCGGGTTGTGAGCCAAACAAGTAATTCAGCGTGACGGGCACCCGTGGAATATCGAGGTGCGGGACGGTGATGGGGCCGAGGCCGACGCTGACCGTGGTGGCGGCCAGGTCGATCTGGGGAATCGGGATGCTCGGCACAGTGAAGCTGTCGATGGCGACGTTGGCGCTGAACTCGGGGCGGATCGCGGGAATGTCGATGGCGGGGATAACGACGGAGCCCAGTCCGCCGGTGAGGGTGAGGTCCAGGAACGGCGTTTGGGGAAGCACGGCGGGGCGGTAGGAGAAGCCGAGCAGGCCCTGGTAGTCGCCCCGCCAGAAGGCGCCGTTGCTGTAGTTACCGGAGATGAAGGCGCCGGTGTTGACGTCGCCGGAGTTGGCCACCCCGGTGTTGATGTCACCGGTGTTCAACCAACCCGTGTTGACACTGCCCGGGTTGAAACCGCCCGTATTGGCCTGCCCCGCGTTGAAACTGCCGGTGTTGTAGCTACCCGCATTGACCACACCCGTGTTGAACCCACCCGCGTTGAACAACCCCGTGCTGACAATCCCCGAATTACCGATCCCGGTATTATAACTCCCCGAATTGAACACCCCCCAGTTCCCGGTGCCAGAGTTAAAGAACCCCACATTACCGGTCCCCGAATTAAACAACCCCACATTCCCGCTGCCGGTATTGAAACCACCGAACCCGGTCAGATTATCACCGGTCAACCCAATACCGAAATTCCCACTGCCGGTGTTAGCGAACCCAATATTGCCCACACCCATATTCGCCAAACCGAAATTGTAGCTGCCGGCATTACCAAACCCGATATTACCCAAACCCATCAGACCCGGCGTTAACCCCGAATTCCCGAGCCCAAAGTTGCCCCACCCGACATTGCCCAACCCGACATTGTTGCCGCCGATATTGCCGCCACCCACATTGAACCCACCGACGTTGCCCGCACCCAGGTTAAAGTCCCCGACATTGCCCAACCCGACATTGCCCAACCCCACATCGGCCAACCCGAAATTGAGGACCAGACCCTGATGCAGCGCCGTCCCGCTCGCCAACAATCCCGACAACTGCTGACCGACACTACCCAAACCCGACACCAACGCCGGCGCACCCAACCCCAACACGCTGGTGTTGAACAGCCCCGACATGCCAGAGCCGAAATTCAGCACACCCGAATGCAGCGTGCCGGCGTTGAAAACACCCGAACCCCCACCCAGCAACGCCGACGGAGCCTGATTCCAGCCACCCGACACCATCGCGCCGACATTCCCAAACCCCGACACCCCACCCGCACCGGAGTTGAAGAAACCCGACGACGGAGCACCGGTCGTATTCCCGAACCCCGGCACGGCGGGAAGGTCGATGAGGATGTGAACGGGGCCGAGGGTGAGGTCGAGGTTGAGCTGCAGCGGAATTGGGTCGATCGTGTAGCCGTTCGGGAAGATGGTGAAGTCCGGGATGCCGGCGAAGGCATCGACATGCACCGGGATTTTCGGGAAGGTGAGGCCGTCCGGGAAGAGGGTGAAACCCGGGATGCCGCCGTCCACATCGATGCGCAGGGGCACCGATGGAATGGTCAGCCCCGGAATGTGGATGGGCGGGATGCTCAGGTTGAGCACCGAAAATGATGGGCCAGAGGCGCCCAGCTGGATGGTGGTCGGGGCGAGCGCGCCCGAAAATGGGCCGATTACGTTGTTACCGGTCGCGAAGTCGACGGTGGAGATAAACACATTGGACGTTGCCGGAATGACGAACGGCGGTGGTGCGGGGCCACCGGGGGCTGTGGAGAACGACTCGATGACCGTGGCGGGAATGTTCATCGGCGGGAAGATGACGAGGGGGCCCAGGTCGAAGGTTTCGTGGTAATCCAAGGCGATCGGCGCAACGGTAATCGGTGCCACGGTAAATGAGCCCAGGTCGATGGTTTGGTCAATGTCCAGCAGCGGGGGGATGTGAACGTGAATCGGATCGATGTGGATGGGGCCCAGGTTCACGGTTTCGCGGAGATGCACGAGGTGGGTTTGCGGAATCAGCGGGCCGACCGGGAAGCTGAAGTCGAGCAGGCCCTGGTAGTCGCCCCGCCAGAAGGCGCCGTTGCTGTAGTTACCGGAGATGAAGGCGCCGGTGTTGACGTCGCCGGAGTTGGCCACCCCGGTGTTGATGTCACCGGTGTTCAACCAACCCGTGTTGACACTGCCCGGGTTGAAACCGCCCGTATTGGCCTGCCCCGCGTTGAAACTGCCGGTGTTGTAGCTACCCGCATTGACCACACCCGTATTGAACCCACCCGCGTTGAACAACCCCGTGCTGACAATCCCCGAATTACCGATCCCGGTATTATAACTCCCCGAATTGAACACCCCCCAGTTCCCGGTGCCAGAGTTAAAGAACCCCACATTACCGGTCCCCGAATTAAACAACCCCACATTCCCGCTGCCGGTATTGAAACCACCGAACCCGGTCAGATTATCACCGGTCAACCCGATACCGATATTCCCACTGCCGGTGTTAGCGAACCCGATATTGCCCACACCCATATTCGCCAAACCGAAATTGTAGCTGCCGGCATTACCAAACCCGATATTACCCAGACCCATCAGACCCGGCGTTAACCCCGAATTCGCCAACCCGACATTGCCAAACCCGACATTGCCCAACCCGACATTGTTGCCGCCGATATTGCCGCCACCCACATTGAACCCACCGACGTTGCCCGCACCCAGGTTAAAGTCCCCGACATTGCCCAACCCGACATTGCCGCCACCGAGGTTGCTCAACCCCACGTTCGGGCCGACGATCCCGACCGCGGAATTGAAGCCCGAGATCAGGTTGTTGGCGATGCTCCCGTCGAACAGGCCCAACAGTCCCACACCCAGGCCCGGGACAGCCAAACCGCTGAAGGGATCCGACGTGGTGGTGGTGGAGTTCCCTGAGCCCGGCTCGGTGATGATCGGGATGTTGATGGGGCCCACCGGGATTGTGACGTCCACGTTCAGCGGAATTGCGGGCAGCACGGTGGCCGGGATGAAGACGGCGTCCTCGAGGTTGATGGACACGTCGATAGGCAGGATTTCGTGCAGAATCATTGACTTTACGGTGGATGCCGGGGAACCGAAAGAGAAGTTGAGCGGTATGGATTCACTGACAGTGGGCAACGGGATACTGAGTCCCGCCATGGTGATGGGAATAGAACTTCCCGGAATTACAATCGGATTCAGTTCGATGCCGTCTCTGAAGTCAAACAAGAAAAGAGTCTGACCGACCGACATGAACAGCTGGGCGGGCTGGGTCTGTATATTCGTGATTTGGATTCCGGAGATATCGATGCTTCCCGTGATGCCCAGGCCGGACAGCAGGGTAGTGGCCGGGGCGTTAAAACTCACATTGACGTTTCCGTCGAGGCCAAAATTGATGGCGGGGATGGGGATGTCCGGGACGGTAAAGGGGCCGACCTCGAGGTTTCCCGTGACGGTCAGGAGGGGATTTAGCGCATCCACAACGGTGGTGGTCGGGATGCTGATGGGGCCGATGCCGCCGTTGAGGGTGAAGTGAAATGGAAACAGCCCGCTGGTGAGGCCAAAGCCGCCTGGGACCGCCGGAATGGGGCCGTTGGCCGGGGTTGGCGGGATGTAGTCCCACCGGAACGGGAAAGGGCCAATAGAAAGGGTGGTGTGCAGGTCCACCGGGATGCGGTCAACCGTGAAACCCTGCGGGAACACGGTGAATCCACCGGTGCCGACGGAGAAGTTGGTGAGGCTGACCACGGGGTTTTCCGGGAACGCCAGGCCGCCCGGGAATAGCGTGATGCTGTCCAGGCCGCCGGTCAGGTTGACGGTCACCGGTGTTTGGTCGGGAACGGTGAGGCCGGCCGGGAACAAGGCCAAGGACGATGTGGACAGATTGAAAGTCGCGCCGAACGGGCCGGGGATCGTGCCCGGGCCGCCGTAGCTGCCGATGATGGGTCCATTGATCTGCAGGTCGCTGATGCTGAGGTAGAACGACCCGGAGGGGAATTTCGCGCCGGGTGGGCCTAGCGGCGGGCCGTAGTGGTCGATCGTGATGAACGGGTCCGGCAAGACGACCGGGTCCGCGGTGATTTCTGCCATGGCGGTTTGCCCGAAAAGAACAAACGCGGGATTCACGTGAAAACCCTCGAGGCCGACGGTTCCGGTCACGTGGATCGGGATCGCGGGAATGGTGATCTCCGGGAGAGTGAATTCGCGGATCCCGATGAATCCCCCGGTGATTTGTATGTCGAATGCCGGAATATCGATGGGCTGGACGTGGATGGGACCGATCCCGCCAATCACCTGCAGGTCAATGGGGATTTCGGAAATGGTGAAAAGGGTGCCGGGGGTGAAGGGGGCCAGGACGTTGATGTTGTTGCCCGTTAAGAAGAAACCGGTGTTGTGGCTTCCCGAATTGAATACGCCCAAATTCCCGGTGCCGGAGTTGAAGAACCCGACATTGCCGGTACCCGAATTGAACAATCCCACATTCTCGCTGCCCGAATTGAAACCACCGAACCCAGTCAGATTGTCCCCGCTGAGCCCGATACCGATATTCCCGTTGCCGGTATTGGCCAACCCGATGTTGCCGATGCCCATGTTCGCCAGGCCGAAATTGCTGCTGCCGGCATTGCCGAACCCGACGTTGTCGAACCCGATATTGCCCAATCCGAAGTTGTTGCCGCCCAGCGCGCCGCCCGACAACATCCCCGACAACTGAGTACCTACATTGCCGATACCCGACATCAACGTGCCGGAGTTGAAATAGCCCGAAACCGTTCCCGGCAACACCTGCATGGCCTGGGTGGACTGGTTAAACCAGCCCGAGGTGTGCGCGCCGACGTTCCCGAATCCCGACACCCCGCCGGCGCCGGTGTTAAAGAAGCCCGAGGACGGGGCGGTGGTCGAATTCCCGAACCCCGGCGACGCCGGAACGTTGCCGCCCACGATGTCGACGGGCCCGACGCCGCCGATGGCGTGCAGGTTCAGGGGGATGTTGTCGATGGTGATTGCCGGGGTGCTCAGGGCGTTGATGTGGCCAATCACGTTGATCGCCAGCGGAAGTGGTTGCTCGGGAATCGAGAATCCCGGAATGGTGAAGGCCTCGGTGCCTGCCGTTACGCCAAGAGTCAGGGTGAGCGGCCCCCCGGTGGGAATGCTGAGGCCAACCGGGAAAAGGGTGAGGGCTGGGGTGGAATAACTGAAGGTTACTGGGATGGAAAACCCGGTATTGATATGTATTGGGCCGATCAAGGTTGTGGGAATGGGGGAAGGGCTGAGGGCGACCTGTTGGATTTGGGGAATTGTTATGGACGAGACGGGCCAGGCCAGCGTGATGGTTTGGTTGAAGTTTTGTGCCGGCCACAGGGTGATGGGATTGATTTTGATGGGGCCGATCGAAATATTGGGTATGCCGACGCCGAGCGAGATTGCCGGGACGTTGATGGGCGGGACGACCAAGGGTCCGAGGTAGAGGGTTTCGTTGATGTTGATCGGGATGTCGGGAAGTATGTGGATGGGCTCGATAGTGATGGCGCCGACACCACCGTTTATGTCCAGGCTGAGGGGAATGACAGGAAGAACGTTCGCTCCCGAGGAGAAGCCGAGCAGGCCCTGGTAGTCGCCCCGCCACAAGACGCCGTTGCTGTAGTTACCGGAGATGAAGGCACCGGTGTTGACGTCGCCGGAGTTGGCCACCCCGGTGTTGATGTCACCGGTGTTCAACCAACCCGTGTTGACACTGCCCGGGTTGAAACCGCCGGTATTGGCCTCCCCCGCGTTGAAACTGCCGGTGTTGTAGCTACCCGCATTGACCACACCCGTATTGAACCCACCCGCGTTGAACAACCCCGTGCTGGCAATCCCCGAATTACCGATCCCGGTGTTATAGCTCCCCGAATTGAACACCCCCCAGTTCCCGGTGCCGGAGTTAAAGAACCCCACATTACCGGTCCCCGAATTAAACAACCCCACATTCCCGCTGCCGGTATTGAAACCACCGAACCCGGTCAGATTATCACCGGTCAACCCAATACCGAAATTCCCACTGCCGGTGTTAGCGAACCCAATATTGCCCACACCCATATTCGCCAAACCGAAATTGTAGCTGCCGGCATTACCAAACCCGATATTACCCAGACCCATCAGACCCGGCGTTAACCCCGAATTCCCGAGCCCAAAGTTGCCCCACCCGACATTGCCCAACCCGACATTGTTGCCACCGATATTGCCGCCGCCCACGTTGTAGCTCCCGACGTTGCCGGCCCCCACGTTGTAGCTGCCGACGTTGCCGCTTCCCGCGTTGAAGAGGCCAACGTTGGCCAAACCCAGATTGACGGCGAGCGACTTGGCCGGCTCGGCGGCGGCCGCCAGGCTTGCCAGCGGCGAGCCAAACGGCGCCAACGCCTCGGCCGCCGCCGAGGCGCCGGTGTGGTACCCCAGCATCGCGGCCACGTCCTGGGCCCACATCAGCTCGTAGTCGAACTCCGCGGCCGCGATCGCCGGCGTGTTCTGGCCGAACAGATTCGATAACGCCAGCGACACTAACCTCGACCGATTGGCCGCGATGACGAAGGGGTCCACCGTCGCGGCCAACGCCGCCTCGAACACACCCACCACCGCCCGGGCCTGCCCGGCCGCCGACTCGGCGGAGGCCGCCGCCGCGCTCAACCACCCCGCATACGGGGCGGCCGCCGCCGCCATCGCGACCGAGGACGGCCCCTGCCAGATACCACCGACCAGCCCCGAGGTCACCGACCCGAAAGCCGCCGCCGCCGAGCCCAGCTCGGCGGCCAGCTCATCCCAGGCCGCGGCCGCCGCCAACAGGGGGCCCGGACCCGCCCCGGTATATATCAGCAGGGAGTTGATCTCTGGCGGCATTACGACAAAACTCATGCCGCCAGCCCTTTCCCGTGCGTTCCCAACATCGCTGTCAACCGGTGATCAGGGTGTTGCGCCGGCGCCGCCGAGGCCGCCGTCGCCGCCGAACCCTGGCTCCGTGCCTGAGTTGGGCTGGCCGGCCTGCCCTTTGCCGCCGGCGCCGCCGGCCTTGGCGCCGCTGTTGCCGCCGTTGCCGCCGTCACCGCCGTCACCGCCGTCACCGCCGAGGCCGGTCGCGCTCTGAGTGCCGCCGCCAATGCCGCCCTGGCCACCCTTACCGCCGTTGCCACCGAAGCCGCCGTCCGGGGCGTTGCCTCCGCCACCGCCCGCGCCGCCAAGGCCGCCGTTGCCGCCGGTGGAGCCGCCGCCATTGCCGCCCTGCCCACCGAGGCCGCCCTGGCCGCCGGCACCGGCAAAGACGCCGTCGCCGCCCCGGCCGCCGACACCGCCGTTGCCGCCGCCACCGGCCACGGTGCCGACGGTACCGCCGCCGTTGGGGCCGCCCTGACCGCCGTCGCCGCCGAAGCCGCCCTTGCCGCCGAAAAAGCCGCTGCCGCCTTGGGTGACGGAGCTGTTGCCGCCGACGCCGTCACCGCCGTGGCCACCGTCGCCGCCCTTGCCGCCCTCGCCGGAGCTAAGGCTGCCGTTTCCGCCGGCGCCGCCAGCGCCACCGGCCCCACCGGAACCGCCGACGATGCCGCTGTTGGCGCCGATCGAGCCCCCGTTGCCGCCGGCACCGCCGTTGCCGCCCTTGCCGCCGTCGCCACCTGAGCCGTTGGGGTTGCTGCCACCGGCGCCGCCCTTGCCGCCGTTGCCGCCGGGGGCGCCCGTGACCCCGATGGAGGCGGGGCCGCTGGTAGCGCCGAAGCTCCCATCACCGCCATTGCCACCGGCGCCGCCCTTGCCGCCTGAGCCGGTGGCGTTACCCCCGGCGCCACCGTTGCCGCCGGAGCCGCCGGCGCCGCCGCGGCTGCCGCTGCCCGGGTTGGTGGCAGGCCCACCGTGGTCACCGTTGCCCCCGTCGCCGCCCTTGCCGCCAAGCACGACGCCGGTGCCGCCGGCGCCGCCGTTGCCGCCGTTGCCGCCGGCGCCGCCGCCAATGCCGCTGCCGCTGCCCCCGGTGCCACCGAACCCACCCTGGCCACCTGCGCCGCCGGCGCCGCCCGTGTCGCCGCTGCCGCCGGCGCCGCCGTGGCCGCCGTTACCGGCGTTGCCACCGCGAGCGTTGCCGTTGCTGGAACCGCCGTTGGCGCCAGCGCCGCCCTTGCCGCCCGCGCCGCCGGTGGAGCCAGGGCCGACACCGTCGCCGCCCTTGCCGCCATTGCCGCCTGAGCCGGCGTTGCCGGCATCGCCACCGCCACCGTTGCCGCCGGCACCGCCGTTGCCACCGGCACCACCGGCGCCGCCGTTGCCGGCCGAGCCAGCGCCGCCGTTGCCACCGGCACCACCGCTGCCGCCGTGGCCGCCGGACTGGCCTGTGCTCAGGCTGCCCCCGCCAGCACCGGCGCCGCCGTTGCCGCCGGCCGCGCCGGCGCCGCCCGTGGTGCCGCTGCCACCGCTGCCACCGCTGCCGCCGCTGCCGCCGTTGCCGCCGCTGCCGCCGTGGCCGGCGGCGCTGGAAGTGCCGCCGCCGTTGCCGCCGGCGCCGGCGGCACCACCGGCCAAGCCCGCGACGCCGGTGCTGTTGCCGGAGTTGCCGCCGTTGCCGCCGTTGCCGCCGTCGCCGCCGGTGGCACCGCCGCCGTGGCCGCCGTTGCCGGCGCTGCCGCCGGCACCGCCCTGGCCGCCGGCGCCCGCGGAGCCGTTGCCGCCGTTGCCGCCATTGCCGCCGTTGCCGCCGTGGCCGGCGGTGACGTTGACGACGCCTGAGCCGCTGGCGGCACCGCTGCTGCCGTTGCCGCCCTTGCCGCCGGCGCCGCCCGTCGTGCCGTCGCCGCCGTGGCCGCCGTTGCCGCCGTTGCCGCCGTCGCCGCCCACAGCGTTGCCGAAGGACACGCCGGCGACACCCGCGTTGCCGCCGGCCCCGCCAGCACCGCCCGCGCCGTTGAGGCCAGTGCCCCCATTACCGCCGGCACCACCGGAGCCGGCGTTGCCGGTGGTCGTGCTTTTGCTGCTACCGCCGTTACCGCCAGCGCCACCGGCCCCTCCGGCACCGCCCGCGTCGGTGCCGATACCGCCATTGCCGCCCGCGCCGCCGGAGCCGGCGTCACCGCCCAAACCGACGTTCCCGCCGTCGCCGCCGTTGCCGCCCTTGCCGCCGGCGCCGCCGTCGCCGCCCGTGGTGCTGACGCCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCGAGGCCGCCATTGCCTTCGGGGCCTCCCGGACCGCCGTAGCCGCCGTTGCCGCCGGCGCCGCCAAACCCAGTCTCGGAGACGCCGCCGTTGCCGCCGAGGCCGCCGTTGCCGCCTAAGGAAATGCCGCCACCGCCGTCGCCGCCGCTACCGCCGTTGCCGCCTGTGCGCCCTTCCCCGCCGATGCCGCCCTGGCCGCCGAAGCCGCCGACCCCGCCGGCACCGCCGTCCCCGCCGGCGCCGCCGACACCGCCAACACCGCTAGCAAAGTCGCCCGCGCCGCCGGGACCGCCGGCGCCGCCTGGGCCACCCAACCCGGTGCTAGCGAAGCCGCCGGCACCGCCATTGCCGCCAGCGCCGCCCGTTGTCGCGGCGACGTCAACGGCGCCGCCACCGCCGGCGCCGCCGAAGCCGCCGAGGCCGCCGTTGATCATGCCGGCACCGCCATTGCCGCCGTTACCGCCTTTGCCGCCCGTGCCGAAGAAGCCGGCCTGGTTCAGCGCCCCACCGCCGTTGCCGCCGTTGCCGGCGTCACCGCCGTTGAGGCCGGAGCCGCCGTTGCCGCCGTTGCCGCCGGCCGCGCCGCTCCCGTTGCCGGCGGTGCCGCCCTTGCCGCCGTTGCCGCCATTGCCGCCGTTACCGCCGTTGGGGGTGATGCCGTCGGTGCCGTCCAAGCCCGTCAAGGAGCCGGTGCCGGCCTTGCCTCCGGTGCCGCCGACGCCGGCGTTGCCGCCGTTGCCGCCGTTGCCGCCGGTACCGGGGTTTCCTACGGTGCCGCCGCCCGGCAGCATGGCCCCGCTGTTTAGGCCGTTTTCGCCGGCCCCGCCGTCACCGGCTTTGCCGCCATCGCCGCCGTTGCCGCCGTCGCCGCCGGTGCCCGTGGCGCCGTCGGTGTACCCGGCCGCCTGCGCCTTGCCGCCCGCGCCGCCATTGCCGCCGGCGCCGCCGTCGCCACCGTTACCACCGCTACCGCCGTTCTCGCCGTTTGCGCCGTTAGCATTGGGGCCGGCGCCGTCGGCGCCTCTCTCGCCGGCGCCGCCGATGCCACCCTGGCCGCCGTTACCACCCTTACCACCGTTGCCGCCGTGGCCGGCCAGTGTTCCGCCGGCGCCGCCCGCCCCGCCGTTGCCGCCAGCCCCACCGTCGGTGCCCGAGGTGCCGGAATCACCGCTGGTAGGGCCCGGCGTACCGGCTTGGCCGGCCGCGCCGTTGCCGCCGGCCCCGCCATTGCCGCCATTGCCGACATTCCCGCCGCTGCCGCCCTTGCCGCCGTCACCGCCGTTGCCGCCCGCGACGGTGGGGCTGGCGCCGTTGCCGCCGTTGCCGCCGTCACCGCCGCTGGTGGGTGCGGTGCCATCGGCGCCGGTCGCACCCTTCATGGCTGGAATGGCGCCCTTGCCGCCGGCCCCACCCTGGCCGGCAACGCCCACATTGCCGCCGTTGCCGCCGGCACCGCCGTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATGCCGCCGTTGCCGCCGTTGCCGCCCTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCGCCCCCGTTGCCGCCCTTGCCGCCGTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATGCCGCCGTTGCCGCCGTTGCCGCCGTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGGCCGCCGTTACCACCGGCGCCGCCGTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCACCTCCGTTGCCACCGTTGCCGCCGCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACACCGCCGGCCCCACCCTTGCCGCCAACGCCCACTTCACCGCCGTTGCCGCCGTCACCGCCGGCACCCTGGTTGACGGCCAAGGTCACATCACCGGCGGCACCGGCTCCGCCATCACCGGCCTTGCCGCCGTCACCGCCGGCGCCGCCGTCCCCGGCCTTGCCGGCGGTGCCGGCGACCGCGGTGCCGCCGGCGCCGCCACCACCGCCGTCACCGCCCTTGCCGCCGTTGCCGCCCATACCGCCATCGGCACCGGGCGAACCCAAGGTGGCGGCGTCGAATCCGTTTCCGCCGGCGCCGCCGCTACCGCCGGCACCGCCCTTGCCGCCGACGCCGCCGTCGCCGTGCTGGGCGCCGCCATTTCCGCCATTACCGCCGTGGCCCCCGGCGCCGCCATTGGTGCCGTTACCGCCCGTCGGTTGTAAGGCGGTACCGGTAGCGCCGGTGGAACCCGCATGACCGGCACCGCCGGCGCCGCCGGTGCCGCCGTTGCCGACCAACCCACCATGACCGCCATTACCGCCGGCCCCGCCGGCTTGTAGGGGTGAGTTGGCGGTGGCGCCGATGCCGCCATCGCCGCCGTTGCCGCCGCTGGTGGGGGTGGCGCCGGCGGCACCGTGCGCACCCGCCAGCAGGCCGCCGGCCCCACCGGCCCCGCCCACGCCGGGGTTGCCGCCGTGACCGCCGTTACCGCCGGCACCGTTGTTGACGGCGAAACTCGGATCGCCAGCGCCGCCCTTACCACCGTCGCCGCCGACGCCGCCGGCCCCGCCGGCCCCGCCGTTGCCAACCAATAACCCGCCGCGCCCGCCGTTGCCGCCGGTTCCGCCGTTGCCGCCGTCGCTGCCGTCGCCGCCGTTGAGGCCGGCGGCACCCGGCAGGCCCGCGGCCCCGGCCCCCCCGGCGCCGCCGTTCCCGAACAGCCCGGCGTCGCCACCGTTGCCGCCTATACCTCCGATGCCGCCGATCCCGCCGGCGCCGCCGTTGCCGTAGACAAATCCGCCGGACCCGCCGACGCCACCATTGGTGCCGGCGCCGCCGGACCCGCCGGCCCCGAACAACCAGGCGTTGCCGCCGGCACCACCGTTAGCGCCGGTCCCGCCGGCCCCGCCGGCCCCGCCGTTGCCGTTCAACCACCCGCCGGATCCGCCGACACCGCCGGCAGCGCCGGCCCCGCCGGACCCGCCGGACCCGCCGTTGCCGAACAACCCGGCCGCGCCGCCGGGCCCACCGACTTGACCGGCCGCCCCCGAACCGCCGTTACCGCCATTACCCCACAACAACCCCCCGGCCCCACCGGGCTGCCCGGTCCCCGGCGCCCCGTGAACGCCATCACCGATCAGCGGGCGCCCCAACCACAGCTGTGTGGGCGCGTTGATCGCACCCAACACTTGCTGCTCCAGCGCCTGCAGCGGTGATGCATTCGCCGCCTCGGCAGTCGCATACGCGCTGCCAGCCGCGGTCAGCGAGCGCACAAACTGCTCATGAAACGTCGCCACCCGGGCGCTCAACGCCTGGTACTCCTGCGCGTGGGTACCAAACAACGCCGCGATCGCCGCCGACACCTCATCACCGGCGGCCGCCAACACCTGCGTCGTCGGGCCCGCTGCCGCCGCATTCGCCGCGCTGATGGCCTGCCCAATCCCGGTCAAGTCCGCCGCGGCCGCCGCCACCAGCTCCGGCGCCACCATCAGCGACATGACCATTCCTCCAACACCAATGGCGCGTACAGCCGGCTCGCGCGAGCCTTGACCGCCGGCGGCAACCCGAGCGATCCCATGGCCCTAGGCGGTTCTCGGGCGAACGCCACGTTTAGCGGATCGATTCACCCGGTCGTTGCGTTGCGGCGCAGCAATAGACATCTCGAAGCACTCCGGCTGCCAATCTCGTCGCGTTTATTCTGCTCGTGACCAGCGCAGGAAAGGGGGGGATTACGAAAGTCTTCGGGATCTCAGTGCACAGTGCACACATGTTTAACCAATCACCGTGGCATAACGCACACCAAAGGCCGAGAGCGCGGAAAACGCAGAACATCAATTGGATCGGTTGCTAGCTTTGCCGCACCGTGGTCAGCCGCGCCAGGATCGGTCGGCAATGGCACCACCGGAGCAGGCGAAAGGTACCCGGTTCTAGCCCGTCCCCAACGGGTCAATGGTGGATGCGATATAGACCATGGCCGCCGCGACCGTCACGGTCGTCACGAAATCGATCCCCTTGCTGCGCACCACCAACAGGCCGGCCCGTTCCTCGGACAACACCAACCGCAGCACCGCCGCCACCCCAACGCCGATACCGATCAGCAGCGCACCACGGCGCCAGAAGTTGACCCCCGCCAGGATCGGCCACTGGGCGCCAACAGTGCGCCGCAAAACGGCCCTCACGGTCATCGCCGCTCAGCCAGCTCCACGACACTTGTCAGCAAGGACGCCCGGGGCGAAGGGCGTTCGCCAAGTCTGTAGATGAGCTGCGGGAGATGGCCGACGGCGAGGGTTGAGAAGCGTCAACTTCGATCGTGATGCCTGGGAGGACTTCTTATTTCATACGCGATCGGTGATGCCGCCCTGAAGCCGAGGTCGACGGCAGCGCGAAGACGTTCGAGAAGACGTCGCGGTGAGGTCAATCCCGGTGTGACCAACGGCCGGTTACGGCCCGGTGCCCGCGAACAGCAGGCCCGACAGCTGCTGGCCGACGTTCATAAAGCCCGAGACGAAGGCCGATGTGACCAGGCCAAGCGTGCCCGTGTTGTACACGCCCGAGATGCCCGCGCCACGGTTGAGGATGCCGGAGAGCTGGGTGCCGAAATTGGCGAAGCCCGACGCCGACCCGAGCAACGGATCCGAGATCGCGTTGAGCACCCCCGACATGCCCGACCCGGAGTTGGAGAAGCCGGACCCGCCACCACCGCCGGTGTTGAAGAAGCCCGACGACGGCGCGGTGGTGTCGTTGCCAAAGCCCGGTGCTCCGCCGAACCCGAAAATCGGGAGGCTGACGGGGCCGATGGTGGTGCTGGCGTGTAACTCCACCGGGATCCGGTCGATAACGACCGTCGGGAGATCAAAGGGTGGGGTGCCGCCGGACAAACCGAGGCCCAGCGGGAGTTGGGGAATCAGGGTGCCGCCCGGGATGGTGAAGCCCGGAATGGTCAGCGACAGCGGCAGGCCGATGTGGATGGGTCCGGTGGGAATGGTGAATCCGGGGAAGTGCAGTGTCGTCGGGTTCAAGTTGATGGGTGCCACGGTGAATGGTTGAAGTATGGAGACCTCGCCCCCGGGCATGCCGTCGGGTCCGACCGCGAAGAATGAAAAGCTGGGTCTGACCTTGAATCCGGAGCTGCTTCCGGACGTCATCCTGATCTCCGAGACGGCAGCATCCAAACTTAGGCCAGGGATGGTGAGGGTGATGGGGTCCACGGTGATAGGGCCGACGTCGAAGGTGGGATCGATGCCCAGGTGGATCGAGGGGATGGCGATGTTCGGGATGCTGATCGGCCCGATGTGGCCGATCGCGGCGAAGCCCAACGGGATGGACGGGATGTGGATGGGCGGAATGATGGTGGCGGGGCCGATGTCGCCGGTGACGTCGGCGCCCACCGCGGGGAACAGCGGAATGGGGTACCCGAAGGAGAAGCCGGCCAAGCCCTCGTAATTGCCCCGCCATAAGATGCCGTTGCTAAAGTTGCCCGTGATGAGGGCGCCGGTGTTGACATTGCCCGCGTTGGCGACGCCGGTGTTGGCGTTACCGGTGTTGAACCAGCCGGTGTTGGTGCTGCCTGGGTTGAAGCCACCGGTGTTGGTGTCACCAGCATTGAAGCTGCCCGTGTTGTACGACCCGGCGTTTGCCACACCGGTGTTGAAGCCGCCGGCGTTGACCAACCCGGTGCTGGCCACCCCGGAGTTGCCGATACCGGTGTTGTAGCTGCCGGAGTTGAACAACCCGAAGTTGGCAGTCCCGGAGTTGAAGAAGCCGATATTGCCTGTGCCGGAGTTGAACAGGCCAATGTTGCCAGTGCCGGAGTTCAAGCCGCCGATGCCGGACTGGTTGTCGCCGGTGAGCCCGATCCCGAGGTTGTTGGTGCCGGTGTTGCCAAACCCGATGTTGCCCAGGCCCATGTTGGCCCAGCCGACGTTGCCGCTGCCGGCGTTGCCCAGCCCGATATTGCCCATGCCGGCCAGGCCCGCCGCCAGACCCGAATTCCCGAACCCGAAGTTGGCATCGCCGATATTGCCGAACCCGACGTTGCCGCCGCCGATGTTGCCGAAGCCCAGGTTCACGTCGCCAATGTTGCCGAATCCCAGGTTCACGTCGCCAATGTTGGCCGCACCCAGGTTGAGGTTGCCGATGTTGCCGAGGCCGACGTTGCCGTTGCCGACGTTAGCCAACCCGATGTTGACGATGGTGATGGGGTTTTGCCCCACGTTGGAGGCCAACAAGCCCGACAGGTGATCACCGACGTTGCCCAGGCCCGACACCAACGCCGGCGTCCCAAGCGGCAGCGTGCTGGTGTTGTAGATCCCCGACAGCCCCGAACCGAGGTTGAGCACGCCGGAGTGCAGTGTGCCGACGTTGGCAATACCCGAACCCGCGCCTGCCAAAGCGGTGTGCGCCTGGTTCCACCACCCCGACATGTTCGCGCCGAAGTTGCCGAAACCCGAGCCCCCGCCCGCCCCGGTGTTGAAGAAGCCCGACGACGGAACGGTGGTGGTGTTCCCAATGCCCGGGGTGGGCGGGATGTTGATCAGCGGGATGTCGCCGGCGATGACGTAGAGTTCGCCGTCGGCGTTCGCCGGGATCTCCGGGAACGTGATCGCCGGAATGGTGGCGCCGGGGGTGCCGACGAACACATCCAGGTTCAGCAGCGAGTTCGCCGGGAACGTCAGACCACCGGGGAACAGGGTGATCGCGTCGATGCTGCCCGGCACCTGGAAACCCAACGGGATCTGGTGAATATTGAGCGCCGGGGTGTTGAACGCCTGAGATGCCGCATTGAAGACGGCATGCACCGGGCCGGTCGTGCTGAGCGTCGGGATTCCCGAGATGATATTGCCGCCGACGAACAGGTCACCGGCGTTGTAGATTCTGCCGACCGAGTACCACGTTGGGCCGATCGCACCGGATGACGTCCAGACGATAAACGGCTCTATTTCGCTGGTCGCCCCGACCGACGCGGCCATATCGAGGACCGCTCGTGCGGCGGTCAGGGCGGGAATGGTGACCGAGGGGACCGCGATGGGGCCGAAGCCGACGCTTCCGGTGACGTTCGGATTGAGGGCGGGAATATCGATTTGCGGGATGGTGAAGGCGCCCATCGCCGCGTTGCCGGTCAGGTGCGCGTTGATCGCCGGAACCGGGATGGGCGGGACGACCACCGGGCCGAAGGCCCCGGTGAAATGCGCGTCCAGGATGGTGATCCGGGGAACGTCGAGGCTGTAGGAATAGCTGAATAGGCCTTCGTAGTTGCCCCGCCACAGGATGCCGTTGCTGAAGTTGCCCGACATGAGGGCGCCGGTGTCGACATTGCCCGAGTTCGCGATGCCGGTGTTGGCGTTACCGGTGTTGAACCAGCCGGTGTTGATGCTGCCCGGGTTGAAGCCACCGGTGTTGGTGTCACCGACATTGAAGCTGCCCGTGTTGTACGACCCGGCGTTGGCCAGACCCGTAGTGAAACCACCGGCATTGAAAAGCCCAGTACTGCCCGTTCCGCTATTACCGATGCCGGTGTTGAAGCTGCCCGAGTTGAACAACCCCCAGTTTCCGGTCCCGGAGTTGAAGAACCCGATGTTGCCGGTGCCGGAGTTGAACAGGCCAATGTTGCCGGCACCGGAGTTCAAGCCGCCGATGCCGGTCTGGTTGTCGCCGGTCAGCCCAATCCCGAGGTTGTTGGTGCCGGTGTTGGCGAACCCGATGTTGCCCACACCCATGTTGGCCAGGCCAACGTTGGTGCTGCCCGCATTGCCCAACCCGATATTGCCGATGCCGAGCGCCGCCCCCAGGCCCGAATTGCCAAACCCGACGTTGCCGTGGCCGATATTGCCGAAGCCGACGTTGGCGTTCCCGATATTGCCCAACCCTAGGTTGAGGTCGCCGAGGTTGGCCGCGCCCAGGTTGAAGTCCCCAACGTTGCCCAACCCGAGGTTGTAGTTGCCGACATCGGCCAACCCGAGGTTGATGATGGGGCTTTGGGTCAACGCCGTCCCGGCCGCCAACACCCCCGACAGCTGCTGGCCCACGTTGCCGGCACCCGACACCAGCGCCGGCGTCCCCAAACCCACGATAGCGGTGTTGTACAGCCCCGATATCCCCGAGCCGACGTTCAGCACACCCGAGTTCAGCGTGCCAACGTTGAGAACGCCCGAGCCCGCGCCCGCCAACGCGGCATGCGCCTGGTTCCACCAGCCTGAGCTGCCGGCCCCGAAGTTGCCGAAACCCGACACCCCGCCCGCGCCGGAGTTGAAGAAACCCGACGACGGGGTGGCGGTCGCGTTCCCGAAGCCGGGCGTCGGCGGAACGATGATGATCGGAACGCTGCTGTCCGGCACGCTGATGTTGAGGGCCAGGCTCAGTGGCAGCGGATCGATCGTGAAACCACCCGGGAATATCGTGATCGGATCCAGCACGCCGGACGCATCGATGGTCAACGGGATCGCATTTTGCGGGATGTTGAGGCCACCGGGGAACAGCGTGAAGGCCGGAAGACCGCCCGACACATCGATCTTGAGCGGGATAGGCGATGTCGTGATCGTTGGGATGGTGACGGTTGGGAGGGTTAGTGCGAGGCTACCGGTGGTTGCGCTGCTGGGACCGGTATGGATCAGGATGCCCTGAGTGGGTGCGGTGACAAAGCCACCACTCATTCCGGTTGAGTTGGACGCCCCAACGATCCAGTTGTCGCCGAGCGCATTCACGAACAGCAACGGAAGTCTGAAGGGCGGCGGGGCGGGGGCCGGGGGCGTGTCGAGCGGAATCGTGTAGGTCTGACCGCCGATCGTCATGCTCGGCAGGAAGACGATGGGCGGGATGACCATCGTTTCGTGGATGTCCAGCACCACTGCGGGGACATCGATGGGCTCGATCCTGAAGGGCCCGATGTTGACGAGTTCGTGGATGTCGAACAGCGACATGCCGGGAATATCGATCTGATCGATGTGGACGGGACCGAGGTTGAGGGTTTCGTTGATGTCCACCAGGGTGCTGCCGGTGATTTCGATGCTGTAGGAGAAGCCGACCAGCCCGTGGTGATCACCGGTCCACAGCGCGCCGTTGTTGAAGCTGCCGGAGTTGAACGCGCCGGTGTTGACATTGCCCGTGTTGAAGCCGCCGGTGTTGGTGTGGCCGGCGTTGAACCAGCCGGTGTTGACATTGCCAGGGTTGAAGCCGCCGGTGTTGGTGTTGCCCGCGTTGAGGCTGCCGGTGTTGTAACTACCGGCATTGGCCAGACCCGTGTTGAAACTCCCGGCATTGAAAAGCCCGGTACTGCCCGTTCCGCTGTTACCGATGCCGGTGTTGTAGCTGCCCGAGTTGAACAACCCCCAGTTTCCGGTCCCGGTGTTGAAGAACCCGATGTTGCCGGTGCCGGAGTTGAACAACCCCAGGTTGCCGGCACCGGAGTTCAGGCCGCCGAACCCGGTCTGGTTGTCGCCGGTCAGCCCGATCCCGAGGTTGTTGGTGCCGGTATTGCCGAACCCGATGTTGCCCAGGCCCATGTTGCCGAAGCCGACGTTGTTGCTGCCGGCGTTGCCCAACCCGATGTTGCCGATCCCCGGCAGCGCCCCCAGGCCCGAGTTGCCGAACCCGACATTGCCGTGGCCGAGGTTGCCGAACCCGACGTTGCCGTCCCCGAGGTTGCCCAACCCCAGGTTCTGCCCGCCGAGGTTGCCACCGCCGAGGTTGAGGTTGCCGAGGTTGCCCGCGCCCAGGTTGACGTCGCCGACGTTGGCGAAGCCGAGGTTGTAGCTGCCGACGTTGCCCAGGTTGACGATGTTCAGCGGATTCAGGTGCCGCAGCTCGGCGATCGCCGCGTCGATGATGCTCGGCTGCCCGGAGCCGCCCGACCCGCCGCTGGTCAGCATCGCCAGCAGGCCATCGATGGACACCCCCGACACGTGGTTGCCCAGGTTGCCGAAACCCGAGATCACCGCCGGCGCGGAGCCCAGCGTGCTCACGTTGAACATGCCCGAGATGTCGACGCCGGAGTTCAGCACACCGGATGCCAGGCTGCCGGCATTGCCCAGGCCGGAGAGCGTCCCCACCATCGGACTCGAGGCCTGGTTCAGCAAGCCGGACACCCCCGCGCCGAAGTTGGCGATGCCCGAGCCGCCACCGCCGCCGGTGTTGAAGAAGCCCGACGACGGCAGCTCGGTCGAGTTGCCAAAGCCCGGCAGCGCCGGAATGTCGATGATCGAGATGTTGATGGGTCCGGCGCTGCTGAGAACGTCGAAGTTCAGCGGAATCGGGTCGATCCTGGTGCCGGTGATGGTGACCGCCGGAATGTCGACGGACACATCGATCGGCACGACCTCCGACATCGAAATTCCGTTGATAGTGGAGGCCGGGATGTCGATCGGCGGAATGTCGATGGGTATGGATTGGCTGAACGAGATTGCCGGCAATTCGATGGCGTCGATGGTCTGCTGCAGCGGCAGGGCCAATCCGCCCAGCGTTGCCGAAGTAAGGGGTATGGCGACCTGTATCTGAACCGAGATTGTGGGATCGGGAAATTCATTTGGGAACGCGTCGTGGAGGAACTGAAGCTTGAGGTTAACGTTGAACGGATTGAGCTGGACGTTTGAGACGGTGATCGGGCCGAACCTGAATTGTCCGGTAATGCCCAGCGCAGAAAGCAGGGTGGTGGCCGGGGCGGTGAAGCCGGCGTCGGCGGCACCGTCGAAGTCGATGTGGATTGCCGGAATGGGGATGTCCGGCACGGCGAAGCCGTAGTTCGCTTGTCCCGTGAGGCCCAGGTGGATGGGGGGAAGGATCGTGGTGTCCGGGATGATAATGGGGCCGATGCCGCCGGTTGAAGTCCAGTGGATCGGGAATTCGGGAATCGTGATGCCGACGTTCAGGCCGAACAGGCCCTCGAAGTTGCCTCGCCACAAGATGCCGTTGCTGTCGTTGCCGGTGATGAAGGCGCCGGTGTTGACGGTGCCCGAATTGGCGACGCCGGTGTTGGCGTTGCCGGTGTTGAACCAGCCGGTGTTGATGCTGCCCGGGTTGAAACCACCGGTGTTGGTGTCACCCACATTGAAGCTGCCCGTGTTGTACGACCCAGGGTTGGCCACACCGGTATTGAAATTACCGGCATTGAAAAGCCCAGTACTGCCCGTTCCGCCATTGCCGATCCCGGTGTTGTAGCCGCCCGAGTTGAACAACCCGAAGTTCCCGGTCCCGGAGTTGAACAACCCGACGTTGCCGGTGCCGGAGTTGAACAACCCGATGTTGCCGGCACCGGAGTTCAAGCCGCCGATCCCAGTCTGGTTGTCCCCGGTCAGCCCAATCCCGAGGTTGTTGGTGCCGGTGTTACCGAACCCGATGTTGCCCACACCCATGTTGCCGAAGCCGACGTTGCCGCTGCCGGCATTGCCCAACCCGATGTTGCCCACCCCGGCCAGGCCCGCCGCCAGACCCGCATTGCCCAACCCGAAGTTGGCATCGCCGATATTGCCGAACCCGACGTTGCCGCCGCCGACATTGCCCAAACCCACGTTCAAGTCGCCGATATTGGCCGCACCCAGGTTGAAGTCCCCGACGTTGCCGAAACCGACGTTTACGCTGCCCACATCGGCCAACCCGAGATTGATGATGAGGCTCTGGTTGAGTGCCGTCCCCGCCGAGGACAACCCCGACAGCTGCTCACCAACATTGCCGATGCCCGAGACCACCGCCGGGGTCCCCGGCGGCAACCCGCCGGTGTTGTACAGCCCCGACACACCCGAGCCGAAGTTCAGCACACCCGATCCCAGCGAACCGAAATTGGCGAAACCCGAACCCGCCCCAGCCACCTCGGTCTGCGCCTGGTTCCACCAACCCGAGCTGCCCGCACCGAAATTCCCGAAGCCCGACACCCCACCGTCGCCGGAGTTGAAGAAACCCGACGACGGAGCGGTGGTCGTGTTGCCAAAGCCCGGGGTCGCCGGGATATTAACGCCGTTGATCAGGATAGGGCCGACAGTGACGCTGGCGCCGAGGTTCAGCGGGATGCGGTCGATCGTGATCGGCGGGGTGCTGAAGCCGTCAATCTGGCCGTCTATGTCGATCGTCAGCGGCAGCGGCGCAGCGGGAATGGTGAAGCCCGGGATCGTGAATCCCAGCGTGCCGATCGACGCGCTGGCCAGCAGCGCCAGTGGATTGTTGGGAATACTGATGCCATTCGGGAAGATCGTTACTGCCGGGGTACTCCAGTTGACGGTCACCGGGAATGACTGGTTAATTCTGGTGTCGATATTAAGGTTACCTAATTGGAGGGTGACGTTGCCGGCAAGATCTTTGATTTCGATTCCTGAAATGTTGACGACCCCCAAGCCAAAGAAGGGGCCGACGGGGAAAGTCGTGTTGAAGTTCTGAGCCGGGAACAGGGTGATGGGCGAGATGGTGATGGGGCCGACGCTGATAGGTATGGCCGTACCGCCACCAAAAGCGGGGATCACGATGTCCGGAACGACCAGCGGGCCGAGGCTGAAGGTTTGGTGAATGTTGAGCGGGATGGTGGGCAAAATCTGGATCGGCAACACGGTGATGGGGCCGACGCCGCCGTTGAGCTCGAGACCAATGGGGATCGCCGGAATGGTCGATCCACCGGAGAGCCCCCACAGGCCCTCGTAGTCACCCCGCCACAGCACACCGTTGCTGAAGTTGCCCGAGATGAACGCGCCGGTGTTGACATTGCCCGAGTTGGCGATGCCGGTGTTGGTGTTGCCGGTGTTCAGCCAGCCGGTGTTGACGTTGCCCGGGTTGAAGCCACCCGTATTGGTGTTGCCCGCGTTGAAGCTGCCCGTGTTATAGCTACCCACGTTGGCCACACCCGTGTTGAACCCACCAACGTTGAACAACCCGGTACTGGCCGTCCCCGCATTACCGACACCGGTGTTGTAGCTGCCCGAGTTGAATACCCCGAAGTTGCCGGTCCCCGAATTGAAGAACCCGATGTTGCCGGTGCCGGAGTTGAACAACCCCAGATTACCGGTTCCTGAATTCAGGCCCCCAATGCCAGTCAGGTTGTCCCCGGTCAACCCGATCCCGATGTTGTTGCTACCCGTGTTGGCAAAACCGATGTTGCCCACACCCAGGTTTGCGAGGCCGTAGTTGCTGCTGCCCGCATTGCCCAACCCAATATTGCCCATGCCCGGCGGCAACCCAAGACCCGAGTTGCCGAACCCGAAGTTGGCGTTGCCGATATTGCCGAAACCGAAATTCCCGCTACCGGCGTTGGCAGCACCCAAATTCTGCGCACCGACATTGGCTGCGCCCAGGTTGAATATCCCGACATTGCCCAACCCGACGTTGTAATTACCGACATTGCCCAAGCCCGCGTTAAGCCTCAACATCTTCGCGGGTCCGGCAAATAGAGCATTGAGGAACGCGCCGACACCACCCCCCAACGCCTGCGCCGGTGGGCTGAACGCCGGCAACGCCGCGGCAGCAGCCGACGCGCCGGAATGGTAGCCGGCCATCGCCGCCACATCGGCGGCCCACATCAACTCGTACTCGGCCTCGACGGCCGCGATCGCTGCGGCGTTCTGCCCCAGCAGGTTCGACATCGCCAACGCCCGCATCGCCATCCGGTTGACCGCCACCGCCGCCGGATCCACCGTCGCCGCCAACGCCGCCTCAAACGCCGCCACCGCGGCCCGCGCCTGCCCGGCCACCGCCACGGCCTGCGCCGCCACCGAACCCAACCACCCCGCATACGGGGCCGCCGCGGCCGCCATCGCCGCCGCCGCCGCACCCTGCCACACCCCCGCCGTCAGGCCCGACGTCACCTGCCCAAACGACACCGCCGCCGACCCCAACTCCTCAGCCAGCCCATCCCACGCCGCGGCCGCCGCCAGCAATGGGCTCGACCCCGCACCCGAATACATCAGCACGGAGTTGATTTCCGGGGGCAGAACTGGAAAATTCAACCGCCCCTACCTCTGCCGCTCACGATGCGTTCACACCTCATCGTCTCACCACGACGTGGTGAGCGCGGGCACTTCGACAAACTAATCTGCAATATCCCGATCGCGTACAAACGTGCCGACATTTGCGGCGCATTAATGCCCATATCGGCTTGTATCTCTTGTAGTGCCGCTTTGACGGGGTGGTGGTCAGGTACGGTGGCCTCGGGAGAGGCTGGAGGGCTCGACGTTTTCGGCTGAGTGTCTGGGCCCGTGAAAGAGATCGTCTGCTCCAGCTTTGTCTCCTGAACTGACCCGGTTTAGGGAATTGGTGGCCAGGTTGCGGAAGTGCGCAGCATCGACGTGTACCTGGGTGAGGCATCGAATCATCGACAAGCACCGGAGCCGCGCGTGAACTCCCGCCGCGTTGTGGTCGGGGATGATGTGGGAGACCGGCCGGCAGTGCTGTGTACGAAGGTTCTCCCACCGCAACGAGTTCACGCACGACGGTCGGCTGGGTGGGCCCTGGAATACGTGAACTCTTCATCAACACAACATGATTGACGATGAAGGGGAGAACCTCCATGCACAACAACGCTAACCCGTGACTGCCGAGAATCCAGGACGGAGCAGGCGGACGCTGGTCGGAATCGACGCGGCGATCACGGCCTGTCACCACATCGCGATCCGCGATGATGTCGGTGCGAGGTCGATTCGATTCAGTGTCGAACCCACGCTGGCCGGACTGCGCACCCTCACCGACAAGCTCAGCGGTTACGACGATATCGACGCCACCGTGGAACCGACCTCGATGACGTGGCTGCCGCTCACGATCGCTGTCGAGAATGCCGGTGACACCATGCACATGGCCGGCGCGCGGCATTGCGCCCGGCTGCGGGGTGCGATCGTGGGCAAGAGCAAGTCCGACGTCATCGACGCCGAGGTTCTCACCCGCGCCAGCGAGGTGTTCGACCTGACGCCGCTGACACTGCCGACGCCCGCGCAGTTGGCGTTACGTCGATCGGTGATCCGACGTGCCGGCGCAGTGATTGACGCGAACCGGTCCTGGCGTCGGTTGATGTCGTTGGCGCGGTAGGCGTTCCCCGATGTGTGGACCGCGTTCGCCGGGTCGTTACCGACCGCGACAGCGGTGCTGGGGCGTTGGCCCGACATCCGCTTGCTGGCCGGCGCACCGACCCGCCACGTTGACCGCCGTCATCGCCGCGCACACCCGCGGTGTCGCCGACACCCCGGCCCGGCCGAGGCCATCAAGACCGCCGCAACCGGCTGGGCCGCGTTCTGGGACGGGCACCTCGACCTGGACGCACTGGCCGTCGATGTCACCGACCATCTCAGCGACCTCACCGACGACCGATGCGCGCGTTGGTGATGCCGGTGACCAAGAAGGTGTTGATCTTGGGTGACTAGTCAATGGTGGTGGCCAGGGTGAGCAGTTCGGGGATCTGCGAGTCGATGCGCCAGGCAGGAAGCGGTGTAGGTGATGGCGCGCCAGGTGGGGGTCCCCGCCGGTGCGCACGGTCGACAGCAGGGTGCGCAGCTCCTCTTTGGCGATCCAGGCCGAGAGAATCTGCGCGCGGGGGTCGACGGCGTTGATCCGATTCCGCATTTTGGCGAAGCTTTTGTCCGACAAGCGTTCCCGGGCGGTCAGCAAGCGACGTCGGTTGGCCCACTGCGGGTCGATCTTGCGGCCGCGCCGGTCGTGGAACGCCCAGGTCACCCGGCGGCGCACCGCGGTCAGCGCGTCGTTGGCCAGCGTGGTCACATGGAAGTGGTCGACGACGAGCTTGGCGTTGGGCAGCAGCCCGGGCGTGCGGATCGCCGAGGCGTAGGCAGCGGCGGGGTCGATGGCCACCGTACTGGATGCTCTCCCGGAACTGCGGTGTGCGCGCTTGCAGCCATGCCAGCACCGCCGCGCCGCCGCGGCCTTCATGCTGCCCCATAAACCCCTGATCACCGGCCAGGTCGACGAACCCGGTATCCCACGGGTCGACCCGTACCCACCGGCCAGTCTTGGCGCAGCGCTCCCATCTGGGTTTTCCTCGCCGTGTCTGGTCAACGCCCAGCACCGGGGTGGGCAACGGCTCGGTCAATACCCGTCTCGGCGTAGGCAACAAACGCCCGATGTGCCGTCGGCCACGACACGGCGTCAGCCTGGGCGACCTCGGCCCACCGAGCGGGCCGCATCCCCGATCGCCTTGGCCATCTGCCGACGCAGCCGCAGCGTGCTGCGGACGCGGGCAGGTACCTGGGTGATGGCCTCGGTGAACGGCCCCAGCTTGCAGTAGTCTTCTCGGCATCGCCAGCGAATTTTGTTCCAGCGCACCATGATGCGGTCTTCGCCATAAGGTAGATCTTTCGGTGAGGTAACCGCGTATTCCTTCACTGATATCGAGACCACCCCCGCACGACGGGCACGCCGCCGCCGTCGGCTCATCGGTGATCACATCGACCACCCGGGTCCCGTCACTGCGGCGCTCGACACGCTCAACCCGTGCTCCTGGCAGCCCGAACAACACTGTCGTAGCGTCAGACACAGCCCTTGGCTCCTTCCTCGGCCTGAATGCTTCGCAACACTTAGACTTCAGAAGGCCAAGGGCCCTCAGCCGCTAAACACGCCGACCAAGATCAACGAGCTACCTGCCCGGTCAAGGTTGAAGAGCCCCCATATCAGCAAGGGCCCGGTGTCGGCGCAAAATTTAGCGTCGTTGCGCCCACACCAGAGTTACCGCCGCACACACGGCGTGACCACCGGCGTGCATTTAAGAATCCGTTAGGGCCCGACGCCGGTGAAGAGCAAGCCCGACAGTTGCTGGCCGACGTTGCCGAAACCCGAGACGACGGCCGCGGTGACAACACCCAGCGCGCCGGTGTTGTACACGCCCGAGATGCCGGCGCCGCGGTTGAGGATGCCGGAGAGCTGGGTGCCGAAGTTGGCGAAGCCCGACGCCGACCCGAGCAGCGGATCCGACATCGCGTTGAGCAATCCCGACATGCCCGCGCCGGTGTTGCTAAAGCCCGAACCGCCGCCAGCTCCGGTGTTGAAGAAGCCCGACGACGGCAGCGTGGTCGAGTTCCCGAAACCCGGCGCCCCGCCGAACCCGGCGATCGGGACGTTGATCGGGCCGATAGTGGTGTCGGCGTGCAGGTCCAGCAAGATCCGGTCGAGAACGATGGCCGGGATGTCGACGGGCGGGATGCCATTGGACAACGCGAGGCCCAGCGGGAGGGTGGGGATCAGGGTGCCGCCCGGGATGGTGAACCCCGGGATGGTCAGCGACACCGGCAGGCCGATGTCGATCGGGTCGAGGGGGATGGTGAATCCCGGGAAGGTCACCGTGCCGGAGGGGATGGAGATGGGCCCCACAAAGTATGCCCCTTGCGTGGACGTTGCACCCCCGCCGCTAGAGGGCGCGATCCGGATTCCGGGGAAGAAGCTGGGCTTGACCCAAATCTCTGAGGTTGGTCCGGACGTGCTGGTGACGGCTCCTTGGGAGTAACTGACGAGCACGGGCGGGGTCCTGACGGTAATGGGGTTGACGGTGATGGAGCCGACATGGACGGCGGGGTCGAGGCCCAAGTGAATGGATGGAACAGAGATGTCCGGGATGGCGATCGGGCCGATGCCACCGACCGCGGCGAAGCCGACCGGAATGGGCGGGATGTGGATGGGCGGCAGCACGGTAATCGGGCCGATCCCGCCGCTGACGTCGGCGCCCACCGCGGGGAACAGCGGGAGGGTGTAGCCCACGGCGAAGCCGGCCAGGCCCTGGTAGTCGCCGCGCCACAGGATGCCGTTGCTGAAGTTGCCGGTGACGAAGGCGCCGGTGTTGACATTGCCCGCGTTGGCCACCCCGGTGTTGGCGTTGCCGGCGTTGAGCCAGCCGGTGTTGATGCTGCCCGGGTTGAAGCCCCCGGTGTTGGTGTCACCGACATTGAAGCTGCCCGTGTTGTAGCTGCCGGCGTTGGCCACACCGGTGTTGAAACTGCCGGCATTGAAGAGCCCAGTGCTGCCCGTTCCGCTATTGCCGACGCCGGTGTTGAAGCTGCCGGAGTTGAACAACCCGAAGTTGCCGGTCCCGGTGTTGAAGAACCCGACGTTGCCGGCGCCGGAGTTGAACAACCCCAGGTTGCCGGCACCGGAATTTAGGCCGCCGATGCCGGTCTGGTAGTCGCCGGTCAGCCCGATCCCAATGTTGCCGGTGCCGGTGTTGGCCAACCCGATATTGCCCACGCCCACGTTGGCCAACCCCCAGTTGTTGCCGCCGGCATTGCCCAACCCCACATTGCCCAGGCCCGGCACGCCCGCGGTCAGACCCGAGTTGCCGACTCCGACATTGCCGTGGCCAATATTGCCGAACCCCAGGTTGCCGGCGCCGATATTTCCGAAGCCCAGGTTGTGCGCGCCGAGGTTGGCCGCGCCCAGGTTGACCTCCCCGACATTGCCGAAACCGGCGTTGTGGCTGCCGACGTTGGCCAACCCGATATTCAGAACGGTCACCGGGTTCACCGCGGACCCGCCGGAAAGCAGCCCCGACAGTTGGTGGCCGACGTTGCCCAGGCCTGAGACCAGCGCCGGGGTCCCCACCCCCAGCGTGCTGGTGTTGTAGATCCCCGAGACACCCGAGCCCAGGTTGAGCACACCGGAATGCAGCGTGCCAACGTTGGCAAAACCCGAGCCCGCCCCCGCCAGCGCGGTGTGCGCCTGGTTCCACCAGCCCGAGGTGCCCGCGCCGAAGTTGCCGAAGCCCGATCCCCCGCCCGCGCCGGCGTTGAAGAAGCCCGACGACGGGGTGATGGTGCTGTTCCCAATGCCCGGGGTGGGCGGGATGTTGATCAGCGGGATGCTGCTGGCGAGGACATACACCGAGCCGTCGGCGCTCGCCGCGATCTCGGGCCAGGTGATGGCCGGGATGTCCACGCCGCCGGCGCCGGCGGTCACGTCCAGGTTCAGCAGCGAGGTCGCCGGGAACGTCAAACCACCGGGGAAGAGGGTGATCGCGTTGACGCTGCCGGGCACCTGGAAGCCCAACGTGATCGGGCCAGTTTCGAGCTGCGGAGTGGTAAACGCCCCGCTGGACGCGGAAATGGTGAGATGGCTTCCGTCGCTCGTGCCGGCGCCGAAAACGAGTGGGCCGGTGGCGTAGGGCGAACCGTCGGCCGATCCGAATGAATAGAAGGTTATACCAAGGCCATTAGTGCCTTGAGTCCACATTTCGAAGGGATCTATCCTCATCTCCGCCCCAACCGAGGCGTTGATTATTTGCTCCACAATGACACTCACCGGCGGAATGCGCACGGACCCCACAACGATGCGGAAGGCGGCGCTTCCGGTGATGTTTGGGGTGAGTGCGGGGATGTCGATCTGCGGAATGGTGAATGCGCCCATCGCGACGTTTCCGGTCAGGTGCGCATTAACGGCCGGCACCGGGATGGGCGGGAGGACCACGGGTCCGAAGCCGCCGTCGAGGTGGGCGTCCACGATGGTGATCCGGGGCACGTCGAGGCTGTAGAACAGGCTGAACAGGCCCTCGTGATCACCCCGCCACAACAGGCCGTTGCTGAAGTTGCCCGACATGAACGCGCCGGTGCCGACGTTGCCCGAGTTGGCGATGCCGGTATTGGTGTGGCCGGTGTTGAACCAGCCGGTGTTGATGGTGCCCGGGTTGAACCCCCCGGTGTTGGTGTCGCCGGCATTGAAGCTGCCGGTGTTGTAGCTGCCGGCGTTGGCCACGCCGGTGTTGAAGCTGCCGGCATTGAAGAGCCCAGTGCTGCCCGTTCCGCTATTGCCGATGCCGGTGTTGAAGCTGCCCGAGTTACCGATGCCGAAGTTGCCGGTCCCGGAGTTGAAGAACCCGATGTTGCCGGTGCCGGAGTTGAACAAGCCGATATTGCCGGCACCGGAGTTCAGGCCCCCGATGCCGGTGAGGTTGTCCCCCACCAGCCCGATCCCGATGTTGCCGGTGCCGGTGTTGGCCAACCCGATGTTGCGCACGCCCTGGTTGGCGAAACCATAGTTGGCGCTGCCGGCATTGCCGAACCCCGTGTTGCCCAGGCCGGCCGCGCCGGCGGTCAGACCCGAATTGCCGAAACCGATATTGCCGTGGCCGACGTTGGCGAAGCCGAGGTTGCCGGTGCCGACGTTGCCCAGCCCCAGGTTTTGCGCACCGAGGTTGGCCGCGCCCAGGTTAACGTCCCCGACGTTGCCGAACCCGACGTTGAAGTTGCCCACATCCGCCAACCCGATGTTGAGGATGGGGATCTGGTTCAACGCGGTCCCGGCCGCAGACACGCCCGACAGCTGATGGCCGACGTTGCCGAGGCCCGACAGCACCGCCGGCGTCCCGAGCGGCAACACGCTGGTGTTGTAGATCCCCGAGACACCCGAGCCGACGTTGAGCACACCCGAGCCCAGCGTGCCGACATTCAACACCCCCGATCCCGACCCCGCCAGCGCGCTCGCCGCCTGGTTCCACCAGCCCGACAGGTTCGACCCGACGTTTCCGAACCCCGACACCCCACCGGCGCCGGAGTTGAAGAACCCCGACGACGGGGTCGCCGTGGTGTTGCCGAACCCTGGCGTCGGCGGGACATCGATGATCGGGATGCTGCTGTCGGGCACGGTGAGATTCAGCGCCAGGTGCAGCGGCAGCGGGTCGATCGTGTACCCACCCGGGAAAATCGTGATCGGATCCAGCGCGCCGGACGCATCGATCGTTAACGGGATGGCGTTCGTGGGGATCGTCAGGCCACCCGCGAACAAGGTGAAGGCCGGCAGACCACCGCTGATGTTCACGTCCAACAGGAATCTCGTGGTAGCGATTTGCGGAATCTCGAAACCCGGAATAGATATCTTGAGCTCGCCGGTCGTTCCGGGGCCAGGGCCGGTGTGAATGGTGATGCCCTGGGTGGGCGCCGGGAAGGGGTCTCCGAAATTGGGAATCGCCGCGGTCGACCCGAGGATCCAGTCCTCGCCTTCGAAGCGCATGCTGATGAGCGGAAGCGTCATGGTTGACCCGGGTGAGGCGGGGATGTCCAGCGGAATGGTTCTCGTCTGTGCGGGAATTGTGGTGGCGGGCACCAGGACGATGGGATCCATGTGGATCGATTCGTGGATCTCTAGCGGTATCGCGGGAACATCGACCTGCGGGATGGTGAAGGGTCCGATCTCGACGATTTCGTGGACGTCGAACAGCGACATGCCGGGGATGTCGATCTGCTCGATGTGGATGGGGCCCAGGTTGAGGGTTTCGTTGAGGTCCAGCAGGGTGCTGCCGGCGATGTCGATGCTGAAGGAGAAGCCGACCAGCCCGTGGTAGTCACCGGTCCACAGCGCCCCGTTGTTGAAGCTGCCGGAGTTGAACGCGCCGGTGTTGACGTTGCCGGTGTTGAACAGGCCGGTGTTGGTGTGGCCGGTGTTGAACCAGCCGGTGTTGACGGTGCCCGGGTTGACGCCGCCGGTGTTGAAGCTGCCCACGTTGAGGCTGCCGGTGTTGTAGGAGCCGGCATTGGCCAGACCGGTGTTGAAGTTCCCCGCGTTGAACAACCCGGTGCTGGCCGTGCCCGCATTCCCCACACCGGTGCTGTAACTGCCCGAGTTGAACAGCCCGAAGTTCCCGGTCCCGGTGTTGAAGAACCCGATGTTGCCGGTGCCCGAGTTGAACAACCCGAGGTTCCCGGTGCCCGAGTTCAGGCCGCCGATCCCGGTCCGATAGTCCCCGGTCAGCCCGATCCCGATGTTGCCGGTGCCGGTGTTGGCCAACCCGATATTGCCCACACCCACGTTGGCCAACCCCCAGCTGCCGCTGCCGGCGTTACCCAACCCCACATTGCCCAGGCCCCCGCGCCCGCGGTCAGGCCCGCGTTGCCGAATCCGAAATTGCCGGCACCGATGTTGCCGAACCCGAGGTTGCCGGTCCCGACGTTGCCCAACCCCAAGTTGCTGCCGCCGAGGTTGCCGGCGCCGACGTTGATGTTGCCGACGTTGCCCGCACCCAGGTTGAACTCACCGGCGTTAGCCAAACCGAGGTTCACCCCGCCGACATTGCCCAAGGCCAAAGCGTTGCCGATGTCGAGGTGCTGCAGCTCGGCGATGGCCGCGTCGATGATCTGATCGAACACGGACTCGGCAGGTGGGAAGGTGAGGATCGCGATCAGGCCATCGATGGACACCCCCGACATATGGTCGCCGAGGTTGCTGAACCCCGAGATCACCGCCGGGGTGGTGGCGTCCAGCGTGCTCACGTTGAACAGCCCGGAGATGGCGGTGCCGGAGTTCAGCACACCCGAGGCCAGGGTGCCGGCATTGCCCAGCCCCGAGAGTGTCCCCACCAGTGACCCCGCGCCGGCCTGGTTGAGCAGGCCCGACACGCCCGCACCCAAGTTGCCGATGCCCGATCCGCCGCCGGCACCGGTGTTGAAGAACCCCGACGACGGCATCTGGGTCGAGTTCCCGAAGCCCGGCGCCGCCGGGATGTCGATGATCGGGATGTTGAGGGGTCCGGCACTGGTGCGAATGTCGAAGCCCAGCGGGATCGCGGAAATGGTGGTGCCTGTGATCGTGACCGCCGGGATGTCCACGGACGCATCGATCGGCACCACTTCCGACATTGAAATCCCATCGATGACCGAGGCCGGAATATCAACAGGTATGCGGATAGGAATCGACTCACTCAACGAAATCGCATCCAGGGGGATGGGCTCGATCTCCAGGGGCACACCGATCCCGGCCACCACGATTGGCTCAAGATGAATTGGTCCGAGTTGGCCCGTGATAGGACCAAGAACGGGCAGGCCTAACGTGAAATCCATGGGCGGAATATCGATATTCGAGCGCGTGATGGGGCCGAAGCTGATGAAGCTACCGTTATTCTTCAGGGCGGACAGCAGGGTGGCTTCCGGGGCGGTGAAGCCGACGGTGACGACGCCATTGATGCCGATGTGGATGGCGGGGATGGGGATGTCGGGCACGGTGAAGCTGTAGTCCGCGTCGCCGGTGATCTGCAGGTGCAGCGGCGGAAGGATCGTGGTGTCCGGGATGACGATGGGGCCGATACCGCCAGTCGTGGTGATGCGGATCGGGAATTGCGGGATCGTGATGCCATAGGACAGGCCGAACAGGCCCTCGTGGTCGCCGCGCCACAGCATGCCGTTGCTGTCGGTCCCCGACATGAGGGCGCCGGTGTTGCGGGTGCCCGTATTCATAATGCCGGTGTTGAACCAGCCGGTGTTGATGTCGCCCGGGTTGAAACCACCGGTGTTGGTATCACCGACATTGAAGCTGCCCGTGTTGTACGACCCGGGGTTGGCGATGCCGGTGTTGAAATTGCCGGCATTGAAGAGCCCAGTACTGCCGGTTCCGCTATTACCGATGCCGGTGTTGAAACTACCGGAGTTGAACAGTCCGAAGTTGCCGGTGCCGGTGTTGAAGAACCCGACATTGCCGGTGCCGGAATTGAACAATCCGATATTGCCACTACCCGAGTTGAGGCCGCCGATGCCGGTCTGGTAGTCGCCGACCAGCCCGATCCCGATGTTGCCCGTGCCGGTGTTGGCCAACCCGATGTTGCCCACACCCAGGTTGGCCAGCCCCCAGTTGTTGCTGCCGGCATTGCTCAACCCCACGTTGCCCAGGCCGGCCAGGCCCACCGCCGGACCCGAGTTGGCGAACCCGACGTTGCCGGCACCGATGTTGCCGAACCCGACGTTCCCGCTGCCGAGATTGCCCAGGCCCAGGTTCTGCGCGCCGATGTTGGCCGCACCCCAGTTGAGGTCCCCCACATTGCCCAACCCGGTGTTGAACGCGCCCACATCGGCCCACCCGATATTGACAATGGGGCTCCGGTTGAGCACGGTCCCATTTGCCAAGAACCCCGACAGCTGCTGGCCGAGGTTGCCGATGCCCGAGACCACCGCCGGGGTGCCCGCTCCCAGGGTGCTGGTGTTGTACCACCCGGAGATCCCCGAGCCGACGTTCAGCACGCCCGAGCTCAGCGTGCCGGCATTGGCAACTCCCGAGCCCGCCCCTGCTAACACGTCGTGCCCCTGGTTCCACCAGCCCGACGTGCCCGCGCCGACGTTGGCGAACCCCGATCCACCGCCGCCGCCGGTGTTGAAGAACCCCGACGATGGGGCCGTGGTGGTGTTGCCGAACCCCGGCACCGCCGGCACATCGATGATCGGGATCGGGATATCGCCGATGAGGATGGTGCCGTCGAAGGTCGCCGGCACGGTGTCGAGGGTGAACCCGTCGGGCAACAGCGTGAACGCGTCCAGCCCCACGGACAGTCCGGTGACCCCGGCGGAGGCCCGCGGAAAGGTCAGCCCACCCGGGAAGAAGGTGAACCCGTCGTTGGCGACCTCCATACCCACCGTCACGGGGGTTTGCGCGGGAATGGTGAAACCATTCGGGAAAAGCGTCCACGGGGTGGTGTCCAAGTTGAGGGTTAGGGGAATTGGTGTCGGGGTGACCAATATCTGACCGCTAACCGTGAGGCCGGGCACAATGATGTTCTCTAGGAACAAGACACCGGCAACAACTTGGAACGCATCAATGGTGATAAATGGGTCACTGAGGCGGAACGGCTCGAGAAAAAGCCCTATCGAACCGGCGAGCGGGTCAAGAGCGCGAATCGGCGAGATGGTGTTTGCGGCCAGGTCCACGCTTCCGGTGATGCTGGCGATGGGAAGTGAGGGAATGCTGATCGGTGGGACGGTGAACGGACCCAGGCCGACGGTGGCGTCGGTGATCTCGACGTGCACGGCGGGTACCGGGACGGGCGCCACATGCAGCGGGCCCACCCCGCCGATCGCGTGCACGGTGACCGGGAATTGGGAGATCGTGGGCCCGACGCGGACGCCGACCAGGCCCTCGTAGCCGCCCCGCCACAACAGGCCGTTGCTGTAGTCGCCCGTCATGAAGGCGCCGGTGCCGAAGGTGCCCGCGTTGGCCAACCCGGTGTTGGCATGCCCGGTGTTGAACCAGCCGGTGTTGATGCCGCCCGGGTTGAAGCCACCGGTGTTGGTGTCGCCGGCGTTGAAGCTGCCCGTGTTGTAGTCACCAGTGTTGGCGATGCCGGTGCTGAAGCTGCCGGCATTGAAGAGCCCGGTGCTGGCCGTTCCGCTATTACCGATCCCGGTGTTGAAGCGGCCGGAGTTCCCGATGCCGAAGTTGCCGGTCCCGGAATTGAAGAACCCGACGTTGCCGGTGCCGGAGTTGAACAACCCGATATTGCCGATGCCGGAGTTCAAGCCCCCGATCCCGGTCCGATGGTCCCCGACCAGCCCGATCCCGATGTTGCCCGTGCCGGTGTTGGCAAACCCAATATTGCCCACACCCATGTTCGCCAAGCCATAGTTGTTGATGCCGGCATTGCCAAAACCAACATTGCCCACCCCCGCCGCGCCGGCGGTCAGGCCCAAGTTGGCAAACCCCAGGTTGCCATGGCCGATGTTGCCCAACCCCAGGTTGCCGTCCCCGACATTGCCCAGGCCCAGGTTGTGCCCACCGATGTTGGCCGCACCCAGGTTGACGTCCCCGACATTTCCGAACCCGGTGTTGAAGTTGCCCACATTGGCCAACCCGAGGTTGCCGGCGAGCATCGAGCGCAGCGTGGTTCCCGCCGCCGACACCCCCGACAGCTGCTGGCCCAGGTTGCCGATGCCCGACACCGCCGCCGGTGTCCCGAAAGGCAACACGCTGGTGTTGTAGAACCCCGAGATCCCTGAGCCCAGGTTGAGCACACCCGAGCCCAGGGTGCCCACGTTGCCAACACCCGAACCGGCCCCCAACAGCGCGCTCGGCGCCTGGTTCCACCAGCCCGAGCTGCCCGCGCCGACGTTGCCGAAACCCGACACCCCACCCGCACCGGAGTTGAAGAATCCCGACGACGGGGCCGTGGTGGTGTTCCCCACTCCCGGCGCCGCCGGGATATGAAGGCCCTGGATCGTGATGGGGCCGATCGTGACCCCGCCCCCCACGGTCAGGGGGATGCGATCGATCGTGATCGGCGGGGTGCTGAACCCGTCGATCTGGCCCTCGATATCGATCGACAACGGCAACGGCTGCGCGGGAACACTAAATCCCGGGATGGTAAAGCCCGGGTTACTGATCGACACACTCACCAGCAACCCCAAAGGATTATCGGGAGCACTGATGCCATTCGGGAACAGCGTGATCGGAGGGGTATCCCATCTGATCGTTAAATCAATCTGTGGATTGGTGGGTCCGGGAATGGTGGTGTCGATAACGATAGGGCCGATAAAGCTGACAAGCTGACCGTTAGAATCAAAGGTTTGGATTTGTGGAATTGTGATTTTCCCTAAACTGAAGGTGGGAAAGGGCAATTGGTTGACAAATGTCTGTTGGGCAAACAGGGTGATGGGTGTGATGGTCAGCGGGCCGATGTTGATGGGTATGCCGATACCGCCGCCGAAGGCGGGGATCACGATGTCGGGAACCACCAGCGGGCCCAAGTTGACGGTTTGGTGAATGCTGAGCGGGATGGTGGGCAGGATCGGGATGGGCTGGATGGTGATCGGGCCGATGTCGCCGTTGAGCACCAGGCCGATGGGAATTGCGGGGATCGACGAGCCGGCGGAGACGCCGAACAGGCCCTGGTAGTCACCCACCCACAGCACGCCGTTGTTGAAGTTGCCCGAGATGAACGCGCCGGTGTTGACGTTGCCCGAGTTGGCGATGCCGGTGTTGGTGTTGCCGGTGTTCAGCCAGCCGGTGTTCACACCGCCGGGGTTGAAGCCACCGGTGTTGGTGTCGCCGGCGTTGAAACTGCCGGTGTTGTAACTGCCCACGTTCACCACGCCGGTGTTGAAATTGCCGGCATTGAACAACCCCGTGCTGGCCGTCCCCGCATTACCGACACCGGTGTTGTAATTACCCGAGTTGAACACCCCGAAGTTCCCGGTCCCCGAATTGAAGAACCCCACATTCCCGGTGCCGGAGTTGAACAACCCGATATTCCCGGTGCCCGAATTCAGGCCCCCGATACCCGTCAGGTGGTTGCCGGTGAGCCCGACGCCGACGTTGTTGGTGCCGGTGTTGCCGAAACCGATGTTGCCCACACCCAGGTTTGCGAAACCATAGTTGCTGCTGCCCGCATTGCCCAACCCGATATTGCCCAAGCCGGCCAGGCCCGCCCCCAGACCGGAGTTGCCGAACCCGACATTCCCGTTACCGAGGTTGCCGAACCCGACATTGGTGCCACCGGCATTCCCGAAACCCAGATTCTGCCCACCCACATTGCCCGCGCCCAGGTTGAACACCCCGACATTGCCCAACCCGACGTTGTAATTGCCGACATTGCCCAAACCCGCATTCAGGCTCAGCGCCTTCGCAGGGCTGGCGAACAGGGCGGTAAGGAACGCGCCGACACCTCCCCCCAGCGCCTGCGCCGGTGGGCTGAACGCCGGCAACGCCGCGGCAGCAGCCGACGCGCCGGAATGGTAGCCGGCCATCGCCGCCACATCGGCGGCCCACATCAGCTCGTACTCGGCCTCGGCGGCCGCGATCGCCGGCGTGTTCTGCCCCAACAGATTCGACACCGCCAACGCCACCAGCCGCGCCCGGTTGGCCGCCACCAGCGCCGGATCCACCGTCGCCGCCAACGCCGCCTCAAAGACCCCCACCACCACCCGCGCCTGCCCGGCCACCGCCTCGGCCGCGGCCGCCACCGAACCCAACCACCCCGCATACGGCGCCGCCGCGGCCGCCATCGCCGCCGCCGCCGCACCCTGCCACACCCCCGCCGTCAGGCCCGACGTCACCTGCCCAAACGACACCGCCGCCGACCCCAACTCCTCAGCCAGCCCATCCCACGCCGCGGCCGCCGCCAGCAACGGGCTCGACCCCGCACCCGAATACATCAGCACGGAGTTGATTTCCGGTGGCAACACCGGAAACTCCATCACCCATTCCCCTTCCCAGCCCGACACCAATCCCCACCGACACCCCCCACATGACGTGTCGACGCCCCGATAATTTTGCTCGCATTGCCAACGGCCCAAGAACGATTCCCCGATAATCGCGGGTACTGGGTGCACTTTGCACAGACGCCGCAGCAAAATGCACATATGCCCTGTCCAGACCGGCGAGCGGCAGGGCGTCATCTGCCCTGACACTTCGACTGCTGGCGGAGTCCGCGAGCATGCTCACCGCCGCGGCGTGCGCCGAACCGGCAGCGCCGGCAAATCCATGACCCCAGCCTGTTCTTGGGTCACTGCGACGTTCACTTTTAAGCGCGACCACGTAAGGTTGGGCAAAGTTCCCAAGCGTTTCACAGTGTCAGTGCACAGTGCGCACCTGATTACCAAAACCCCGAACCTCACTCGAAAGCCGAGAGCGGGTAAAAGTCGTTCAGCGACCTGTCTGGTAGAGAAATCCAGACCCGAGTACATGATCCGGTCGGGATCGTACTTGCGCCGCACTGTGGTCAGCCGCGACAGGTTCGCGCCGAAGTATTGTGACGCCGCGGCGTTGGCCTCCAGGTAGTTGACATAGCCGCCGACCGAAAAGTGTTGCACCGCGTGGTGTGCGTCGCTCAGCCATTTGTTGGCCGTCGCCACCTGGCCGTCGCTGGGGGTGTTGACATACCACTGCACCACAGCGGACTGGCGGCACCAGGGAAATGCCGAGCCCTCCGGGTCCATGTCGCCCACCGCGCCGCCCAGCGAATCGATCAGAGCCGACGCGCGGCCCGCAGCGGGTGGCCATGTTCCGATGGCGGCGACGATGGCTTGGGCCGCGGCCGGATTCGTCGTCCCGATGACATCGGATCCAGCCACGAAGCCCTCCGGCGGATAGGTCGTATGGCCGCCGGCCAGATACCTCACCAGGTCCATACGGCGCAGCGTCTTGTGCTCAACTCCACTGGGTTGCACTCCAACCGCGGACTTGATCGCATCCGCGACAGCCGCGCCGGACCGCGCCGGGCAGCTCGCCAGCACATGACAATTGCCTCCGGATGAGCTGACCGCGGGGTCAACCAGACCCCACGTGGTGCGGTCGGCCCCGGCCAGCCACGTCTGTCAGCCGACCAGCACCTGCGCGGCCGCAGACGGCGCGAAATCGACACGGACGACATCGCAGTCCGCGGTGGGGAACCTCGCGAACGTCATCGATGTCGTCACCCCGAAGTTGCCGCCCCCGCCGCCACGAAGCGCCCAGAACAGCTCCGCGTGGTCGTCGGCAGACGCGCTCACCGCATCACCGCCGGGCAACACCACCGTCGCCGACTTGAGCGCATCGCAGGTCAACCCCGCATGGCGAGAATCGGCGCCTAACCCGCCGCCCAGGGTCAAACCCGCCACACCCACGGTCGGGCAGCTGCCGGTCGGAATCGCCCGGCTCTCACCGGCCAACGCTTGATGGACCGCATAGAGATCGGTCGCGGCCGACACCGTACGTTTCTCGTGGCGCTGTCGAAATGCACCCCGCCCGGTAGGCCCAGCAGATCGAGCACCATGGCGCCATTGGCCGACGAGGCGCCGATGTAGGAATGTCCGCCGCCGCGCACAGCGATCTTGAGCTTGCTGGCCGCCGCTACGAAACCGCCTTCCGGACGTCTGCCTGCGAGGCGACCGTCACCACCGCGGCCGGATTCAAGCCGCTGTAGTTCGAATTGAAGATCTGCTTTCCGCTCGTGAACGCCCTGCCGTTGGCCGGCAGCAGCACCTGCCCGCCTATCGATGAGGCCAGACTGGCCCACCCATCACCCGGTGTTGCGCGCGCCAATATCGTCGGGAAGACCGCCGACGTCGCCGGCGCTCCGACGGCGCCGCGAAGAAACGTCTGGCGAGACATCACGACCGCGATCGTGTCGTATCGAGAACCCCGGCCGGTATCAGAACGCGCCAGAGCGCAAACCTTTATAACTTCGTGTCCCAAATGTGACGACCATGGACCAAGGTTCCTGAGATGAACCTACGGCGCCATCAGACCCTGACGCTGCGACTGCTGGCGGCATCCGCGGGCATTCTCAGCGCCGCGGCCTTCGCCGCGCCAGCACAGGCAAACCCCGTCGACGACGCGTTCATCGCCGCGCTGAACAATGCCGGCGTCAACTACGGCGATCCGGTCGACGCCAAAGCGCTGGGTCAGTCCGTCTGCCCGATCCTGGCCGAGCCCGGCGGGTCGTTTAACACCGCGGTAGCCAGCGTTGTGGCGCGCGCCCAAGGCATGTCCCAGGACATGGCGCAAACCTTCACCAGTATCGCGATTTCGATGTACTGCCCCTCGGTGATGGCAGACGTCGCCAGCGGCAACCTGCCGGCCCTGCCAGACATGCCGGGGCTGCCCGGGTCCTAGGCGTGCGCGGCTCCTAGCCGGTCCCTAACGGATCGATCGTGGATGCGATGTAGACCATGGCCGCCGCGACCGTCACGGTCGTCACGAAATCGATCCCCTTGCTGCGCACCACCAACAGGCCGGCCCGTTCCTCGGACAACACCAACCGCAGCACCGCCGCCACCCCAACGCCGATACCGATCAGCAGCGCACCACGGCGCCAGAAGTTAGCCCCCGCCAGCACGAACCCCACCGCGAAGATCGACCCAACCAGCAGGATCGGCCACTGGGCGCCAACAGTGCGCCGGAAAACGGCCCTCACGGTCATCGCCGCTCAGCCAGCTCCACGACATTGGTCAACAAGAACGCCCGGGTCAACGGGCCCACGCCGCCCGGATTGGGTGACACGTGGCCGGCGAGCTCCCACACATCGGGATGCACGTCGCCGACCAGTCCGTCATCAGTGCGGCTGACGCCGACGTCGATTACCGCGGCACCCGGGCGCACCATGTCAGCCGTCAACAGGTGCGCCACCCCGACCGCGGCCACGACGATGTCGGCCTGCCGGGTCAACGCGGGCAGGTCGCGGGTACCGGTGTGGCACAACGTCACCGTGGCATTCTCCGAGCGCCGGGTCAGCAACAGCCCCAGCGGCCGGCCCACCGTCACACCACGACCGATAACGACCACATGCGCGCCGGCGATCGAGATGTCGTAGCGCCGCAGCAGGTGCACAATGCCGCGCGGAGTACACGGCAGCGGCGCCGGGGTGCCCAGCACCAGCCGGCCCAGGTTGGTCGGGTGCAACCCATCGGCGTCCTTGGCCGGGTCGACGCGCTCCAACGCCGCGTTCTCGTCGAGATGCTTGGGCAACGGCAACTGCACGATGTAGCCGGTGCAGTCGGGGTTGGCGTTCAGTTCGTCGATGGTCTCATTCAGCGTGGCGGTGCTGATGTCGGCGGGCAGGTCGCGGCGAATCGACGTGATGCCCACCTTGGCGCAATCAGCGTGCTTACCGCGCACGTAGGCCTGCGACCCCGGGTCGTCACCGACCAGGATGGTGCCCAAGCCGGGCGTGCGGCCCGCCGCGTCCAATGCGGCCACCCGCTGCTTGAGGTCACCGAAGATCTCGTCGCGGGTAGCCTTGCCGTCCAGCATGATCGCGCCCACGCCAGCCAGTCTGGCATGCGTGTCCGCGGTGCCGATGGCGACGACCCGCTCACGCGCCCACCGTACGGACAACTTGTACCATTGTGGTACAGATTATCCGTACATCTTTCTAAGAGAGGACGCATGAGCATCAGTGCGAGCGAGGCGAGGCAGCGCCTGTTTCCACTCATCGAACAGGTCAATACCGATCACCAGCCGGTGCGGATCACCTCCCGGGCCGGCGATGCGGTGCTGATGTCCGCCGACGACTACGACGCGTGGCAGGAAACGGTCTATCTGCTGCGCTCACCGGAGAACGCCAGGCGGTTGATGGAAGCGGTTGCCCGGGATAAGGCTGGGCACTCGGCTTTCACCAAGTCTGTAGATGAGCTGCGGGAGATGGCCGGCGGCGAGGAGTGAGAAGCGTCAACTTCGATCCCGATGCCTGGGAGGACTTCTTGTTCTGGCTGGCCGCTGATCGCAAAACGGCCCGTCGGATCACCCGGTTGATCGGAGAAATTCAGCGTGATCCGTTCAGCGGGATCGGCAAACCCGAGCCGCTCCAAGGTGAGTTGTCGGGATACTGGTCGCGCCGGATCGACGACGAACACCGGCTGGTGTATCGAGCGGGCGACGACGAAGTCACGATGCTGAAGGCCCGATACCACTACTGATTTGGGGGCTGGTGGTATTCCGGCGGGCTTAAGCTCCCCATGTGGCTCCCGGCAGCTGCGAAGCCCCGGACGTGTTCAACCCGGCCAAACTCGGTCCGCTCACGCTGCGTAACCGGGTCATCAAGGCCGCCACCTTCGAGGCCCGCACACCTGACGCGTTGGTGACCGATGACCTGATCGAGTACCACCGGCTGCCGGCCGCGGGCGGGGTCGCCATGACCACCGTCGCCTATTGCGCGGTCTCCCCCGGCGGACGCACCGGCGGCAACCAGATCTGGATGCGCCCGCATGCGGTGCCGGGACTGCGCCGGCTCACCGAGGCGATACACGCCGAGGGGGCGGCGATCAGCGCCCAGATCGGCCACGCCGGCCCGGTGGCCGACGCCCGCTCCAACCAGGCGACCGCGCTGGCTCCGGTGCGGTTCTTCAATCCGATCGCTATGCGGTTCGCCCAGAAGGCGACCCGCGAGGACATCGACGATGTGCTGGCCGCGCACGCCCATGCCGCCCGGCTGGCCGTCGACGCCGGCTTCGACGCCGTCGAAATCCATTTGGGGCATAACTATCTGGCGAGCGCGTTTCTGTCTCCGCTGCTCAACCGGCGTGATGACGAGTTCGGCGGTTCGTTGCAGAACCGGGCGAAGGTAGCTCGCGGATTGGTGATGGCCGTGCGCCGCGCCGTCCGGCAGCAGGTCGCGGTGACCGCCAAGCTCAACATGACCGATGGCATCCGCGGCGGCATCACAGTCGACGAGGCACTGACCACCGCCAGGTGGCTGCAGGACGACGGCGGGCTAGACGCGATCGAGCTCACCGCGGGCAGCTCGCTGGTCAACCCGATGTATTTGTTCCGCGGCGACGCGCCGGTTAAGGAGTTCGCCGCCGCGTTCAAACCACCGCTGCGCTGGGGCATCCGGATGACCGGCCATAGGTTTTTCCGCGAATACCCCTACCGCGATGCCTATCTGTTACGCGAGGCTCGGTTGTTTCGCGCCGAGCTGACAATCCCGCTGATTCTGCTGGGCGGCATCACCAACCGAACGACCATGGACCTGGCGATGGCCGAAGGGTTCGAGTTCGTCGCGATGGCTCGGGCGCTGCTCGCCGAGCCCGACCTGGTCAATCGGATCGCGGCCGAAGGCAGCCAGGTGCGGTCGGCGTGCACACACTGTAATCAGTGCATGGCCACGATTTATCGCCGCACTCACTGTGTGGTCACCGGGGCTCCATAGCGTCCAGATTGACGCCACCGTGAAGAAGTGCAACCCATTGTGCCGGAAATCCGGTTGACTTCCCCGCGCGAATCCGGCTCAGGCACTATTGACCGCGCGCAGCATAATTTGAACCGATGAGTCGACCCCATCCACCGGTGCTGACAGTTCGGTCCGATCGGTCGCAGCAATGCTTCGCCGCGGGCCGCGACGTGGTTGTCGGGAGTGATCTTCGTGCCGACATGCGCGTGGCGCACCCACTGATCGCCCGTGCGCACCTGTTGCTGCGCTTCGATCGGGGCAATTGGATCGCGATCGACAACGATTCGCAGAGCGGGATGTTCGTCGACGGCCAGCGGGTGTCGGAAGTCGACATTTATGACGGCCTGACTATCAACATCGGGAAGCCCACCGGGCCGTGGATCACCTTCGAGGTCGGCCATCACCAGGGCATCATCGGACGGCTGTCACGCACCCCGTCGTCGCGTCCCGGCTCACCGATCTAGCCCCCTGCCAAGCACAGCCCGTGCGCCGCCGCAAAGGCCACGGCTTGGTCGACGTCGACACGCGCACCCACCAACGACGCGGTCCGCCACAATACCGGGTCCACGGTCGCGCCCCGCAAGTCGGCGTCATCCAGCCGGGCGCCCGTGGTACGGGCACCACTGAGGTCGGCGCCGCGCAGCACGCACTTGCGCAAGTCGGTATCCACCAGGCTGGTCTCTCGCAACCGGCAGCCGGTCAAGTTGAGACCACGCAGATCATTTCCGCCGAGCACGGCGAGCGTGAAATCCACGTCGTCCAACGTCAGCGGCCGCAGCCGGCAAGCCACGAAGACCGAGCCCAACATGCTGCACTGGGCAAATGTGCTGTGCCACAGTGTCGTCCGTTCGAAGGTGCAATTACGAAACGCCGACCCTCGGTGTTGTGACTCGGCCAGATTCACGCCGCTGAAATCGCATTCGCTGAACATCGCCCGTTCGGTGTGCAGGCGGCTAAGGTCCTCGTCGCGGAAGTCTCGACCGGTGAATTCGCAATCAACCCACTGCTGCAACGCTTTTCAACCGCCCGCAGGAGACAGGGTGGCCAGCGCGTATTCGCTCACCGCGATCAGTGCATCGGTCGCCGACCTGCGATTGCGGGCGTCAACATTGATCACCGGAATGTGTGCGGGCAGCGTCAACGCGTCGCGCACCGCGCTAACCGGATACCTTGGCGCGCTGTCGAACTCGTTGATGGCGATCAAGAACGGCAGGTTGCGGTGTTCGAAGAAGTCGACCGCCGCAAAGCTGTCCTGCAGACGCCGGCAGTCGACCAAGACGATCGCCCCGATGGCACCACGCACCAGGTCGTCCCACATGAACCAGAACCGGCGCTGGCCCGGGGTACCGAATAGATAAAGCACCAGATCCTCGCCCAAGGTGATGCGGCCGAAGTCCATCGCCACCGTGGTGCTCCGCTTGTCGGGAGTGGCCTCCAGCATGTCGACGCCGGCGGAGGCATCGGTGACCATCGCTTCGGTGCGCAACGGCATGATCTCCGAAACAGCGCCGACGAATGTGGTCTTGCCGGACCCGAATCCGCCCGCGATGACGATCTTCGTCGACGCGGTGCCGGATGCCTCAGAGTGCTTTAAGGCCACGCAGGGTCCTTCCTATGAGTTCGTGGCGTTCGTCGCGGGTCGATCGGTCGGTCAAGGTCGCGTGCACCCGAAGGTAACCGGACGTGACCAGATCACCGACCAGCACACGCGCCACACCCACCGGCAAATCCAGCCGAGCCGAGATTTCCGCGACCGACGGACTGCCAATGCACAATTGCAAGATCCTGCGTCGCATGTCGTAGGCCGGCCAGCGGCCAGCCGGTCCCGCCGGCAGGGTCTGCACCGGCGCCTGAAGCGGAAGGTCGACGTCGGTACCGGTACGTCCGGCGGTCAGCGTGTAGGGGCGGACCAGGCCCGCCTTCGGTCTATCGCCGGCAGGATTGAACAACGCCGCCCACCCGCTCGACAAGGATGGCCATCTCATAACCGATCTGGCCGATATCGCATCCGGTCGCGGCCAGCGCCGCCAGCGCCGACCCGTCTCCCACCTGCATCAACAGCAGGTAGCCGTTCTGCATCTCAACCACCGACTGCAGCACCTGCCCGCCGTCGAACAGTTGCGCGGCGCCGCCGGCCAGGCTGGCCAGCCCGGACGTCACCGCGGCCAACTGATCGGCGCGTTCGCGTGGTAGATGTTCGCTGGCCGCCACGGGAAGCCCGTCGACCGACACCAGCAATGCATGGGCCACCCCGGGAACCTCGCGGGCGAACTTCGACACCAGCCAGTCAAGCGGGCTGTCCGGCAAGCGGGCTTTCATTGCTGATTGGGTCCCTGACTGCTCTCGCGGGCATGCGACCGCCCGGTGCGCACGCCGCCGAAATGGCTGCTGATGGAGGCACGAACCGCGTCGGGGTCGCGTACCGCAGCCGCGTGCCGCGGCGCTCGGCCGGGATGAAGTCCGCCGTTGGATGCTAGCGCTGCACCCGGATGCTCCCGATCGGGTCCCTCAGGCACCGCCGCCCCCGGCACTAACCGGGCCCCGGGTTCGCGCACCGGCAGGCCGTAGTCCGTGCGGGACTGCACGGGCTTGTCCGCGGCCTCGGCGGCCGCCGACCAGCCGTGGTCCCACACCGACTTCCAGTCCAGATCGGGGCTGTGGGCCAGCTCGTGCGGGTCACCCACCATCTCGGAGAGCATCCGCCGGTAGATGACGTCGTCATCAACCGGGCCCGCCGGTGGCGCGGGTTTGGCGGGCGGCGGCGCCGGTCGCGGTTCTGGTGCGGGCGGTTGTTTGGGCTCCTGTTGAAACCTATCCTCCCACCAGGGTGTTTTCAGCTCGCGCCGCCGCTGCCGCATCGGCTGGGCCGGGACGTCGGCGATGCCCCTGGACCCCGGGGTACGGCGCGGGAGCAACGTGACCGGTGGTAGCGGCCCGATGGCGGCGGGAACGTCCGTCGGATCGGCCGCCGCGGGTTCAGGACACGGCGGCTTGATCGCAAATACCCGCGGCTTTGGCGGCTGCGCTGGGGCCGTCCCCTCGAGCACGGCTAGCGGCAGGTAGACCTCGGCGGTGGTGCCGGTGCCCTGTTCACCGGTCACCGGACCGCGCAGCCCGACTCGGATGCCGTGCCGACCGGCCAGCCGGCCGACTACGAACAGACCCATGTGCCGGGCACTATCCGGGGTGACCTCACCGCCGGCCCGCAGCCGCATATTGGCCATCCGCCGATCGGCATCGGTCATGCCCAGGCCGGAATCCGAGATTCGCAGCAGAACACTGCCTTCGCTGCCGATTGCGGCGGCAACCCGAACGGGTGTGGTCGGTGACGAGTAGCGCAACGCGTTGTCGATCAGCTCGGCAAGCAGATGAATGACGCCACCAGCCGCTGCGCCGACTACCGCACAGTCGGGTACCCTCGCGATGTCGACGCGGCGATAGTCCTCGACCTCTGACACGGCGGCGCTGATCACGGTTGACAGCGGCACCGGCTCGCGGTGGTCACGGGTAATCTGCGCACCGGCCAGCACCAGCAGGTTGGCGCTGTTGCGGCGCAGCCGGGCGGCCAGGTGATCGAGCCGGAAAAGGCTGTCGAGTCGGGCGGGATCCTCCTCGTTGCGCTCCAGTTGGTCGATGACCGACAGCTGCTGGTCGACCAGGGAACGGCTACGCCGCGACATGGTCTCAAACATCTCGTTGACCAGCAGTCGCAACCGCGTTTCCTCGCCGGCCAGCAACAGGGCCCGGGTGTGCAGCTCGTCGACCGCATGCGCGACCTGACCGATTTCCTCGGTGGTGTACACCGCCAGTGGCTCGGGGATCGGCTCGTCGCCGGCGCGGACCGCCGCGATCTCGCCGTCGAGATCGGTATGAGCAACCTTGAGCGCCCCATCACGCAGTACCCGCATCGGCCCGACCAGCGTGCGCGCCACCACCAACACGACGACGATCGCGGTCGCGATGGCGGCCAACACCAGCACGGCGTCGCGAATCGCGGCATCCCGCCGGTCGGTGGCCTGGCTTTGCACCGACTTCGTCACCGCCTCGGTGGTGTCGGTGATCACCTGCTCGGCAATGTCGCGGGTGATCTGTATCGAGTGCAGCAGCTCTGGGTTGTTGACCAGTGCAACGGCCGGATCGGACATGATCGCCATCCTGGTCACCATTTGCTGCTGCAGGTTCTTGGTGTCCGGCGAGCCTGCACCGAGCGCCGCGCTCATCCCGAACAGCGTCGAGGGTTCGGTGCCGGCCAGGGTAACCATCGCGCTGCGCAGTTGCGGCTCGGCAAGGTCGGCGCCGCGAGTCACCAGGATCTCCTGCATCGTCATCTGCCCGCGGGCGCCAACGGCTCGGCTCAAACCCTGCACCTGGGTTCGGATTTGCTCGCTGTCAACCCGCACCGACGCGTCAATCACGTTCTGGGCCGTCAACAGCAGCGGCGCGTAGGCGGTGACCCGATCCCGCAAGCCGATGCTGTCGGCCAGCACCTTATCCAGCAGCGCCTGACCGCCGTTGAGCAGCGTGTTCACTCCCGACCGCACGTCTGCGATGACGTCGGTGTCGGCCAGTCGCGTCTGCAGCTCGTACTTGCGGGCGGTGAAGTTTTTCTGCGCCCCCTCCACATCGTGTCCGGTCGAGCTGGCCAGCACGGCGACGTCCAGCGCCGACATGTATTTCGTGATCGCGGGTATCATTTCGGCGCGCGCGGCGACCAGCCGCAGGCCGCTGGTGCTGGCCATCGCAGCCTCGACCCGCAATCCTGCTAACACCATCGCCACTACCAGCGGCAGAAGCGCGATCGTGAACACTTTCCATCGGACCGGCCAGTTGCGCGGCGACCAGGACGGCGGGCGTTGCTGAGGTTTGCCGCGGGCCGGTTGAGCCGGGGCGGAAATATCAGAAGCGGCCGCCGCGACCGGGATGGTCGGGCGGGCGAACATGGTCACGTGGCCGCGGCCGTGCCACCGGCCGCACCCTTATGCAGCGCTCGAAAAACGGAGAGACTCATAGACTTCCTGCTCATGCCTTGATGCCGTCCGCCCCAGCCGGCCGGGCGCGGACGTAAACAACTGGCAATCCGACGAGTATGACAGCCCACGGCCGAGGTCTCCACCGCTGTCACCGAGCATGTCACCGGACAGGCCGGCAAACGGGCACCGGGCGCTTTGCCATGATCGGCGGATGTTCCGGCTGCTGTTCGTATCTCCGCGTATCGCCCCCAACACCGGCAACGCCATCCGGACGTGCGCCGCAACCGGCTGTGAACTGCATCTGGTCGAGCCGCTCGGCTTCGACCTGTCCGAACCCAAGCTGCGACGGGCCGGGCTGGACTACCACGACCTGGCCTCGGTCACCGTTCATGCCTCGCTCGCGCACGCCTGGGAGGCGCTGTCGCCAGCGCGGGTGTTCGCCTTCACGGCGCAGGCGACGACGTTGTTCACCAACGTCGGCTACCATGCCGGTGACGTGTTGATGTTCGGGCCCGAACCCACCGGCCTGGACGAGGCCACCCTGGCTGATACGCACATCACCGGGCAGGTGCGCATTCCGATGCTGGCGGGCCGGCGCTCGTTGAACCTGTCCAACGCCGCAGCCGTCGCGGTCTACGAGGCCTGGCGTCAGCACGGCTTTGCCGGGGCGGTCTAGTCGCGACCAAGGTGACACCGAACCAGCCGGTATGCGCACAACGAAGCTCATCGGCGTCGGGCGCCGGACAGGAGCACCCAACCGGTGACAGCACACCGAACGCAACCCGGGCGATCACATCGGACCACGACATCCCGGGAAAATCGATGCCGGTGAGCTTGCGCGTCCAGCTACCACCACCGTCAGCGGTGACATCTTCACCGGCAACAACGGCAGCGCAGGCGCAGCTGTCAGCGGCGGCGCGCAGCGAAGGCGTTGCGGTCAATGAATCTGCCGCAAACCCCACGCCCGTTGGCCCATATTGCGCTAGCATCCGGGTGTTGTGATCTCGCAGGTTGCGTGCTGGCAGCCTGGGGGTGGGTTGTGATGTCGTTTGTCGTAGCAGTCCCGGAGGCATTGGCGGCGGCCGCGTCGGATGTGGCGAACATCGGTTCTGCGCTAAGTGCCGCGAATGCAGCGGCAGCCGCCGGCACAACGGGGCTACTGGCAGCCGGTGCCGACGAGGTCTCGGCCGCCCTGGCGTCGCTGTTTTCCGGGCACGCTGTGAGCTACCAACAGGTCGCGGCCCAGGCGACGGCGTTACACGATCAGTTTGTCCAGGCCTTGACCGGTGCCGGCGGATCGTACGCCCTCACCGAGGCCGCCAACGTCCAGCAGAATCTGCTGAACGCAATTAACGCGCCCACTCAGGCGCTGTTGGGGCGCCCGTTAATTGGCGACGGGGCTGTCGGCACCGCCAGCAGCCCCGACGGGCAAGATGGCGGTCTGCTGTTCGGCAACGGGGGCGCCGGCTACAACAGCGCCGCCACGCCCGGAATGGCCGGCGGCAACGGCGGCAACGCCGGATTGATCGGCAACGGCGGTACTGGCGGGTCGGGCGGTGCCGGCGCGGCCGGTGGCGCCGGCGGCAGCGGCGGCTGGTTGTACGGCAACGGCGGAAACGGCGGCATCGGCGGGAATGCGATCGTCGCGGGCGGTGCCGGCGGCAATGGGGGCGCTGGCGGCGCCGCCGGATTGTGGGGCAGTGGCGGCAGCGGCGGCCAAGGCGGCAACGGTCTGACCGGCAACGACGGCGTGAATCCGGCCCCCGTCACAAACCCCGCGCTAAATGGCGCCGCCGGCGACAGCAATATCGAGCCGCAAACCAGCGTCCTGATCGGCACCCAAGGCGGTGACGGCACGCCCGGGGGTGCTGGCGTCAACGGCGGCAACGGTGGCGCGGGCGGAGACGCCAATGGCAACCCCGCAAACACCTCGATCGCCAACGCAGGCGCCGGCGGGAACGGCGCCGCCGGCGGTGACGGCGGTGCCAATGGCGGTGCGGGCGGCGCCGGCGGGCAGGCCGCGTCCGCCGGTAGTTCCGTCGGCGGTGACGGCGGCAACGGCGGTGCCGGCGGTACGGGCACGAACGGGCACGCCGGCGGTGCGGGCGGCGCCGGCGGTGCCGGTGGTCGCGGCGGGTGGCTGGTCGGCAACGGTGGCAACGGTGGCAACGGTGGCAACGGTGCCGCCGGCGGCAACGGCGCCATCGGCGGTACCGGTGGTGCCGGCGGCGTCCCCGCCAACCAGGGCGGTAACAGCGCCCTAGGCACCCAGCCGGTCGGCGGCGACGGCGGCGACGGCGGCAACGGGGGCACCGGAGGCACCGGCGGGCGTGGCGGCGACGGCGGATCCGGCGGCGCGGGCGGCGCGAGCGGTTGGTTGATGGGCAACGGCGGCAACGGCGGCAACGGCGGCACCGGCGGCTCAGGCGGTGTCGGCGGCAATGGCGGCATCGGCGGTGACGGCGCCGGCGGCGGAAACGCCACGAGCACGTCGAGCATCCCCTTCGACGCCCACGGGGGTAACGGCGGCGCTGGTGGCGACGCTGGTCACGGCGGAACGGGCGGCGACGGCGGTGACGGGGGGCATGCCGGCACCGGTGGACGTGGCGGGTTACTGGCCGGCCAGCACGCCAACTCCGGCAATGGCGGTGGCGGCGGTACCGGCGGTGCCGGGGGCACCCATGGCACCCCCGGCAGCGGCAACGCAGGCGGCACCGGCACCGGTAACGCTGACAGCACAAACGGCGGGCCAGGCAGCGACGGCCTCGGCGGGGACGCGTTTAACGGCAGTCGCGGCACCGACGGCAACCCCGGCTAATTACCAGCCGTTCCAGTGCGTCACGCTCTCGGCCGGCAGCCGCTTGGCCGGCCGGAAGTCGATGCCTTGTGTGTAGGCGATCGGAAGCAGCCCGCCTTGGCTGTATTCGTCGTAGGGAATGCCGAGCACGTCGGCCACCTTGTGCTCGCCGTTGTCGAGCAGGTGCAGCGTCGTCCAGCACGAACCCAGCCCGCGGGAGCGCAGCGCCAGGCAGAAGCTCCACACCGCCGGGAACAGTGAGGCCCAAAACGACACGCCACCCACCGCCGACTCGTCTTCCCGGCCTTTCAGGCAGGGGATCAGCAGCACCGGCGCCCGGTGCATGTGTTCGGCGAGATAGGTCGCCGAATCGCGGACCCGCCCCATCCGCTCGCCGCGGGTGTCGCCGTCGGGGTACTCGGGCGCCGGCCCGCTGAGGTAGCCCCGGGCGTTGGCCAGGTAGACGTCGGCGATCGCCTTTTTCTTGGCGGCGTCCTCGACGAACACCCACTGCCAGCCTTGGGAATTGGAACCGGTGGGCGCCTGCAGCGCCAGCTCGAGGCATTCCATCAGCACGTCGCGTGGCACCGGCTTGTCGAAATCGAGACGCTTGCGCACCGAGCGGGTAGTGGTCAGGACCTCGTCGACGGACAGGTTGAGGGTCATGTGGGCAGGCTACCGTTGGGCCATGAGCGTCGAACTGACACAAGAGGTTTCTGCCAGGCTCACGTCCGACCTTTACGGGTGGTTGACCACCGTCGCCCGATCGGGGCAGCCGGTTCCGCGGCTGGTGTGGTTCTACTTCGACGGGACCGACCTGACGGTGTACTCCATGCCTCAGGCGGCCAAGGTCGCCCACATCACCGCCCATCCGCAGGTCAGCCTGAACCTGGACTCCGACGGCAACGGCGCCGGGATCATCGTGGTGGGCGGGACGGCGGCGGTGGTGGCCACCGATGTCGACTGCCGCGACGACGCGCCGTATTGGGCCAAGTACCGCGAGGATGCCGCGAAGTTCGGGCTGACCGAGGCGATCGCCGCCTACAGCACCCGGCTGAAGATCACCCCGACCCGGGTGTGGACGACGCCCACGGGCTGAGCGGGCTGGCCCCCGCTCGCCGCCAGAGTGAAATCCACGACGCGTTTGCGGCGTGTCGCGTCGCCCGTTTCACTGTCGGCGCAGAGGTTCACCGGAAGTCGCGCGAGCGCGCGCCGACCGCCAGGGTGAGGCGGCCCATCCGTTCGGCGACGACGGTGATTGCGCCGCTGGCGTTTTGGACCTGGCCGCGGATCAGCAGCGCCGGCGCCGTGTGCGCGAGCTTGCGGTGTCGCGCCCACACCCCGGGCGTGCAGAGCACGTTGACCATCCCGGTCTCGTCTTCGAGGTTGATGAACGTCACCCCCTGGGCCGTGGCGGGTCGCTGCCGATGAGTCACCGCGCCGGCGATCAGCACGCGGTCGCCGTCGGACACCGATCCCAGCCTCTCGGCGGGCAGCACCCCCATCGCGTCCAGGTCCGCCCGCAGGAACTGGGTCGGATAGCTGTCCGGGGAGACGCCGGTGGCCCACACGTCGGCGGCGGCCAGCTCCAGCTCGCTCATCCCCGGCAGCGCCGGGATGTGCGACGACGAGCCCACCCCGGGTAACCGGTCCGGCCGGCCCGTGGCCGCGGCCCCGGCCGCCCACAGCGCCTCCCGCCGAGACATGCCGAAGCAGCCCAGCGCCCCGGCCGTCGCCAGCGCTTCGACCTGCGGCACGGAAAGCTGCACCCGCGACGTCAAGTCCGGCAGGGAGGTGAACGGGCCGTTGGCTGTTCGCTCCGCGACCAGCTTCTCGGCCAGCTCGGCGCCGAGGTAGCGGACGGCGCCCAAGCCCAAACGCACCTCCGTTCCGGCGTTCTCACACGTGGCGTGCGCCAGGCTGGCATTGACACACGGGCCGTGCACCGCCACGCCGTGCCGGCGGGCGTCGGCCACCAGCGACTGCGGCGAATAGAAACCCATCGGCTGGGCGCGCAGCAGCGCCGCACAGAACGCCGCCGGGTGGTGCAGCTTGAACCACGCCGAGTAGAACACCAGCGACGCGAAACTCAGTGCGTGGCTCTCGGGGAAGCCGAAATTGGCAAACGCCTCCAGCTTTTCGTAGATCCGGTCGATCACCTCGTCGGGGGCGCCGTGCAGCGCGCGCATGCCGTCGTAGAACCGGCCGCGCAGCCGGCGCATGCGTTCGGTGGAGCGTTTGGACCCCATGGCGCGGCGCAGCTGGTCGGCCTCGGCGGCGGAAAAGCCGGCGCAGTCGACCGCCAACTGCATCAGCTGCTCCTGAAACAGCGGCACTCCCAGCGTCTTTCGCAATGCCGGCGCCATCGACGGGTGCTCGTAGATGACCGGGTCGACGCCGTTGCGCCGCCGGATGTAGGGGTGCACCGATCCGCCCTGGATGGGCCCGGGGCGGATCAGCGCCACCTCCACCACCAGGTCGTAGAACACTCGCGGCTTAAGGCGCGGCAGGGTGGCCATCTGCGCACGTGACTCCACCTGGAACACGCCGACGGAATCGGCGCGGGCCAGCATCTCATACACCGCCGGCTCGGAGAGGTCGAGGCGGGCCAGGTCCACCTCGATGCCCTTGTGCTCGGCCACCAGGTCTTTCGCATAGTGCAGCGCCGAGAGCATGCCCAGCCCGAGTAGGTCGAATTTCACCAAGCCGATTGCCGCGCAGTCGTCTTTGTCCCATTGCAGGACGCTGCGGTTGGCCATGCGCGCCCATTCCACCGGGCACACGTCGGCGATCGGGCGGTCGCAGATGACCATGCCGCCGGAGTGGATGCCTAGGTGCCGCGGCAGGTTGCGGATCTGGGTGGCCAGGTCGATCACCTGCTCGGGGATGCCGTCAACGTCGTCGGCCTGCCCGGTCCAGTGGCTGACCTGCTTGCTCCACGCGTCCTGCTGGCCCGGCGAGAAGCCCAGGGCGCGGGCCATGTCACGCACCGCGCTGCGCCCCCGGTAGGTGATGACGTTGGCGACCTGGGCGGCGTAGTCGCGGCCGTATTTGTGGTAGACGTACTGGATGACCTTTTCGCGCTGATCCGACTCGATGTCGATGTCGATGTCGGGTGGCCCGTCGCGGGCGGGCGATAAGAAGCGCTCGAACAACAGCTCGTTGGCCACCGGGTCGACGGCGGTGACGCCCAGGGCATAGCAGACCGCGGAGTTGGCCGCCGATCCCCTGCCCTGACACAGGATGTCGTTGTCCCGGCAAAACCGGGTGATGTCGTGCACCACCAGGAAGTAGCCCGGAAATCTCAGTTGGGCAATGACTTTCAGCTCATGCTCGATCTGGGAGTACGCCCGGGGCGCGCTCTTGGGCGGCCCGTAACGCTCGCGGGCGCCCGCCATGACCAACGACCGCAGCCAGCTGTCCTCGGTGTGCCCGTCGGGAACATCGAACGGCGGCAGCCGCGGCGCGATGAGCTGTAGGCCAAAGGCGCACCGCTCGCCGAGCTCGGCGGCCGCGGTCACCGCCTCGGGGCACCACGCGAACAACCGGGCCATCTCCTCCCCGGACCGCAGGTGCGCCCCACCCAGCGGAGCCAGCCACCCGGCCGCGGAGTCCAGCGACCGCCGGGCCCGGATGGCCGCCATCGCCATCGCCAGCCGCCCACGTGACGGATCCGCGAAGTGCGCCCCGGTGGTGGCGACGATGCCGACACCGAAGCGCGGCGCCAGTCCGGCCAGCGCGGCGTTGCGTTCGTCGTCGAGCGGGTGACCATGATGGGTCAGCTCGATGCTGACCCGGCTGGGGGTGAACCGGTCCACCAGATCGGCCAGCGCCCGCTGCGCCGCGGCCGGGCCACCCTGGGAAAGCGCTTGGCGCACATGGCCTTTGCGGCAGCCAGTCAGGATGTGCCAGTGCCCGCCGGCGGCCTCGGTTAGCGCGTCGAAGTCGTAGCGCGGCTTACCCTTTTCGCCGCCGGCCAGATGCGCCGCCGCCAGTTGCCGCGACAACCGCCGGTAGCCTTCCGGGCCGCGGGCCAACACCAGCAGGTGCGGGCCGGGCGGATCCGGCCGCTCGGTGCGAGCCGTGGCGCCCAGTGACAGCTCGGCGCCGAAGACCGTGCGCACGTCGAGTTCCGCGGCCGCTTCGGCGAACCGCACCGCCCCGTACAGGCCGTCGTGGTCGGTCAGCGCCAGGGCACACAGGCCCAGCCGGGCGGCCTCCTCGACCAACTCCTCGGGCGTGCTGGCCCCGTCGAGGAAGCTGTACGCCGAATGCGCATGCAGCTCGGCATACGCGACGGACGATCCGACCCGTTCCCGGCCCGGCGGCTGGTACGCCCCGCGCTTGCGGGACCGTGGGACGTCCCCATCCGCGTCGAACGCCGGCACCCCGGCATGGCGCGGCTTGCCGTTAAGCACCCGTTCCATTTCCGCCCAGCTCGGCGGCCCGTTGCTCCACCCCACATTCCACAGTATATCGAACAATTGTTCGATACAGCGCAGTTGTTCAGCACATCTTCACCTGCGAAACATGTTCTTAACCGTTTGGGCCTTCTGCTTCCGGTGCGGTCCGGCGGACACTTATACCTGGGGTCGCAAAACGACGGTGGGGACTTGTCATGGCACAACTGACGGCACTGGATGCGGGTTTTCTCAAGTCCCGCGATCCGGAGCGGCACCCGGGCCTGGCGATCGGCGCAGTTGCCGTCGTCAACGGTGCCGCCCCCAGCTACGACCAGCTCAAAACGGTTCTCACAGAACGGATTAAGTCGATACCTCGATGTACCCAGGTGTTGGCGACCGAGTGGATCGACTATCCGGGATTCGACCTCACCCAGCACGTGCGACGGGTGGCGCTTCCCCGGCCCGGCGACGAAGCCGAGCTGTTCCGGGCCATCGCGCTGGCACTGGAGCGTCCCCTCGACCCGGACCGCCCGCTGTGGGAATGCTGGATCATCGAAGGCCTCAACGGCAACCGCTGGGCGATCTTGATAAAAATCCACCATTGCATGGCCGGCGCCATGTCGGCGGCCCACCTGCTGGCCAGGCTCTGCGACGATGCCGACGGCAGTGCCTTCGCTAACAATGTTGATATCAAACAGATTCCGCCGTATGGCGATGCGCGGAGCTGGGCCGAAACGCTGTGGCGAATGTCCGTCAGCATCGCTGGCGCCGTCTGCACGGCCGCGGCACGCGCCGTCAGCTGGCCGGCAGTGACGTCACCGGCCGGCCCGGTCACCACCAGGCGGCGGTACCAAGCGGTGCGCGTTCCCCGCGACGCCGTCGACGCCGTGTGCCACAAGTTCGGGGTGACCGCCAACGACGTCGCGCTCGCGGCCATCACCGAGGGCTTCCGAACGGTTCTGCTGCACCGCGGCCAGCAACCGCGCGCCGACTCACTGCGTACCCTGGAGAAAACCGATGGCAGCTCGGCCATGCTGCCCTATCTCCCCGTCGAGTACGACGACCCGGTGCGGCGATTGCGCACCGTGCACAACCGGTCACAGCAGAGCGGCCGTCGTCAACCCGACAGTCTGTCGGACTATACGCCTCTCATGTTGTGCGCCAAGATGATTCACGCGCTAGCTCGGTTACCGCAACAAGGCATCGTCACCCTGGCGACCAGTGCACCCAGGCCACGCCACCAGTTACGGCTGATGGGCCAGAAGATGGACCAGGTGCTGCCCATCCCGCCCACCGCACTGCAGCTGAGCACCGGGATCGCGGTCCTCAGCTACGGCGATGAGCTGGTGTTCGGCATCACCGCTGACTATGACGCCGCGTCCGAAATGCAGCAGCTGGTCAACGGTATCGAACTGGGTGTGGCGCGTCTGGTGGCGCTCAGCGACGATTCCGTGCTGCTGTTTACCAAGGATCGGCGTAAGCGTTCATCCCGCGCACTCCCCAGCGCCGCGCGGCGGGGGCGGCCCTCTGTGCCGACCGCCCGAGCGCGTCACTGACGCCATCTCCGTCGGCGTTGACCCCCGTGAGAGGGTGGGTCGTGCGCAAGTTGGGCCCGGTCACCATCGATCCGCGCCGCCATGACGCGGTGCTGTTCGACACCACGTTGGACGCCACCCAGGAACTGGTCCGGCAACTCCAGGAAGTCGGTGTGGGCACCGGCGTCTTCGGTAGTGGCCTAGACGTTCCGATCGTAGCGGCCGGCCGTCTGGCGGTGCGGCCGGGCCGGTGCGTGGTCGTCTCGGCCCACTCGGCGGGCGTCACGGCCGCACGCGAAAGCGGATTTGCGCTGATCATCGGTGTCGACCGCACCGGGTGTCGGGACGCATTGCGTCGCGACGGCGCCGACACGGTGGTCACCGACCTAAGCGAGGTCAGCGTGCGCACCGGGGACCGACGCATGTCGCAGCTGCCCGACGCGTTACAGGCACTCGGCCTGGCCGACGGCCTGGTCGCCCGGCAGCCCGCGGTGTTCTTCGACTTCGACGGCACGCTGTCCGACATTGTCGAGGATCCCGACGCGGCCTGGCTCGCCCCCGGTGCCTTGGAGGCACTGCAGAAGTTGGCCGCGCGCTGTCCGATCGCGGTGCTCAGTGGCCGCGACCTGGCCGACGTGACACAGCGGGTGGGTCTGCCCGGCATCTGGTATGCCGGCAGCCATGGTTTCGAATTGACCGCACCCGACGGAACGCACCACCAGAACGACGCCGCGGCGGCAGCCATACCGGTGCTGAAACAGGCGGCTGCCGAGCTGCGCCAGCAACTTGGACCCTTCCCGGGTGTTGTGGTGGAGCACAAGCGGTTTGGCGTCGCCGTGCACTACCGCAACGCGGCCCGGGACCGGGTCGGCGAAGTCGCCGCGGCGGTGCGCACGGCCGAGCAGCGTCATGCGCTGCGGGTGACGACGGGCCGCGAAGTCATCGAGTTGCGTCCCGATGTCGACTGGGACAAGGGGAAAACGCTGCTGTGGGTTCTTGACCATCTGCCGCATTCGGGCTCGGCTCCCCTGGTGCCGATCTACCTCGGCGACGACATCACCGACGAGGACGCTTTCGATGTGGTCGGCCCCCATGGTGTTCCAATTGTGGTGCGCCACACCGACGACGGTGACCGCGCCACCGCCGCACTGTTTGCGCTGGACAGTCCCGCACGGGTCGCGGAGTTCACCGATCGGCTGGCGCGTCAGCTCCGTGAGGCTCCCCTGCGGGCAACGTGAGACGCGGTGCCGCCGCGGGCGATACGCTCCGACCGTCAACGAGGAGGACGGCCATGTGGTTTGCATTGGTGAACCCGGAGATGCTGGCCGCGGCGGCGACAGACTTGGGCGGCATCAGGTCAGGGATCAGCGCCGCCTATGCGCGTCCTCTGCGGTGACCTGGCTGGTAGCTTAGGCACGTCTTTATCGACACCGGGTGCTGCCAGAGAACTCGAGACGCGGCACAGGTCGGCACCATGAGGCGGCGTGCAATGACGAAGATGGACGAGGCTAGCAATCCGTGCGGCGGGGACATCGAAGCTGAGATGTGCCAGTTGATGCGCGAGCAACCACCCGCCGAAGGCGTCGTCGATCGTGTCGCGCTGCAACGCCATCGAAACGTTGCGTTGATCACGCTGAGCCATCCGCAGGCGCAGAACGCACTCAACCTGGCGAGCTGGCGTCGGCTGAAGCGGCTGCTGGACGATCTCGCCGGCGAATCGGGGCTGCGGGCGGTGGTGCTGCGGGGCGCCGGTGACAAGGCGTTCGCCGCGGGTGCCGACATCAAGGAGTTTCCGAACACCCGCATGAGCGCCGCGGACGCCGCGGAGTACAACGAGAGCCTGGCCGTCTGCCTGAGGGCGTTGACCACGATGCCGATCCCAGTCATCGCGGCGGTCCGGGGGCTCGCCGTCGGTGGCGGCTGTGAGCTGGCGACGGCCTGCGATGTGTGCATCGCGACCGACGACGCGCGCTTCGGCATCCCGCTGGGCAAGCTCGGCGTCACGACGGGCTTCACCGAGGCGGACACCGTCGCGCGCCTCATCGGTCCGGCGGCGCTGAAGTATCTGTTGTTCAGCGGAGAACTGATCGGCATTGAGGAAGCCGCCCGCTGGTGATTGGTGCAAAAGGTCGTCGCACCACAGGATTTGGCGGCCGCGACGGCCAAACTGGTCGGCCAGGTCTGTCGGCAATCCGCGGTGACCATGCGTGCGGCGAAGGTGGTCGCCAACATGCACGGCCGAGCGCTGACCGGCGCCGACACCGATGCGCTGATCCGGTTCGGTGTCGAAGCCTACGAGGGGGCGGACCTACGCGAAGGGGTGGCGGCCTTCAGCCAGGGACGCCCACCCAAATTTGATGATTAGCGCCATGACCGATGCTGACAGTGCGGTCCCTCCCCGACTCGACGAGGACGCGATCTCGAAACTCGAGCTGACCGAGGTCGCCGACCTGATCCGCACCCGGCAACTGACGTCGGCAGAAGTGACCGAGTCGACGCTGCGGCGTATCGAAAGGCTTGACCCCCAGCTGAAGAGCTACGCCTTCGTCATGCCGGAAACTGCGCTAGCGGCGGCACGTGCCGCCGACGCCGACATCGCGCGCGGCCACTACGAGGGTGTCCTGCACGGCGTACCGATCGGCGTGAAGGATCTCTGCTACACGGTCGACGCCCCGACCGCGGCCGGCACCACCATCTTTCGTGACTTTCGCCCGGCATACGACGCGACGGTTGTCGCGAGGTTGCGCGCGGCCGGCGCGGTGATCATCGGCAAGCTGGCCATGACGGAGGGGGCCTATCTCGGCTATCACCCCAGTCTGCCGACCCCGGTCAATCCCTGGGACCCGACAGCGTGGGCGGGCGTGTCCTCGAGCGGCTGCGGCGTGGCCACCGCGGCGGGATTGTGCTTCGGCTCGATCGGGTCGGACACCGGGGGGTCGATTCGCTTTCCGACGAGCATGTGCGGCGTCACCGGGATCAAACCGACGTGGGGCCGGGTCAGCCGTCACGGCGTCGTCGAACTTGCGGCAAGCTACGACCACGTCGGGCCGATCACCCGTAGCGCTCACGATGCGGCGGTATTGCTCAGTGTCATAGCGGGATCCGATATCCACGATCCCTCGTGCTCGGCGGAGCCCGTTCCGGACTATGCCGCCGACCTCGCCTTGACACGGATTCCGCGTGTCGGGGTGGACTGGTCGCAGACGACGTCGTTTGACGAGGACACCACGGCGATGCTGGCCGATGTCGTCAAAACGCTCGACGACATCGGATGGCCCGTCATCGACGTCAAGCTGCCCGCGCTTGCGCCGATGGTGGCAGCGTTCGGAAAAATGCGCGCGGTCGAAACGGCGATCGCGCATGCCGACACCTACCCGGCGCGCGCCGACGAGTACGGGCCGATCATGCGCGCAATGATCGACGCCGGACACAGGCTGGCTGCGGTGGAATATCAGACGCTGACCGAGCGGCGTCTGGAATTCACGCGATCGCTGCGTCGCGTGTTCCACGACGTGGACATCCTGCTGATGCCCAGCGCCGGAATTGCCTCGCCCACACTGGAAACCATGCGCGGGCTCGGACAAGACCCGGAGCTGACCGCCAGACTGGCGATGCCGACAGCACCGTTCAACGTCAGCGGTAATCCCGCGATATGCCTACCGGCGGGAACGACGGCGCGCGGAACGCCGCTCGGCGTCCAGTTCATCGGCCGTGAATTCGACGAGCACGTGCTCGTCCGAGCCGGCCACGCATTTCAGCAAGTCACCGGGTATCATCGCCGACGCCCGCCGGTGTGAAAAACCCTCGGCCGCAAAAGGCTTGCGAATGTCGCACCGAAGGTCGCGGCGAATCGCCTTACTGGTATGTTTACGAACACAATCTGTGGCCATCAAGGGAGGACGCGTTGAGCATTAGCGCGGTTGTTTTCGACCGTGACGGTGTGCTCACCAGCTTTGACTGGACACGTGCCGAGGAGGATGTGCGGCGAATCACGGGCCTACCATTGGAGGAGATCGAACGCCGCTGGGGTGGGTGGCTCAACGGATTGACTATCGACGACGCGTTCGTTGAAACCCAGCCAATTAGCGAGTTCCTCTCGAGCCTGGCGCGCGAGCTCGAGCTCGGTTCGAAGGCAAGAGACGAGCTAGTGCGCCTCGACTACATGGCGTTCGCCCAGGGATATCCAGACGCGCGTCCAGCCCTTGAAGAAGCCCGGCGCCGTGGCCTCAAGGTCGGTGTTCTCACAAACAACAGCCTGTTGGTCAGCGCCCGCAGCCTCCTTCAGTGCGCCGCTCTGCACGACCTCGTCGACGTCGTGCTGAGTTCGCAGATGATCGGAGCTGCCAAGCCTGACCCGCGGGCCTATCAAGCGATCGCGGAAGCCCTCGGCGTCTCGACAACGTCATGCCTGTTCTTCGACGACATCGCCGACTGGGTTGAGGGCGCACGGTGCGCGGGCATGCGCGCGTACCTCGTGGACCGTTCCGGACAAACTCGCGACGGCGTCGTTCGCGATTTGTCCAGCCTTGGAGCGATCCTGGACGGCGCGGGACCATGACCGAACGTGACGAGCCGGACATCGCCGACAGGGACGCCTCATTGGTTACTCTCATCGACCAGCCGCAGTGCACTTAGGATGGCAGCCTTAACTACCGTCGCCGAGCAGTAAAGTGTCTTGGCAATCCACAACGGCGCGTATGGCGGTTCGCAGTGTTGCGATAGCCACCCACCCGCGCGACTGATCTGCGCCGACAAGGATGTGCCGCTGTGCCTCTGCCAATGCGCCAGAGCTTGAATGCAATATGCTGTCTCTTCCGCAGTCGCTTGGCCGTCGAAAAATCCCCACGAGCCATCGGGCCTCTGCGTATTAAGAATCCACCCAATCGCATCTGAGCATAGGGCATCATCATAGTTACTGGCAGCACATATCAGATGCGCAGTCGTATAATATGCCGATCGGTGCCACTTATCCCGCCAGCAGAACCGTCCAGGCTCCTTGCTTGATCGGATGAATTCCAGAACCTTTCGTACTCGTGGATGACATTTGTCGTAGCCCGCCTGCTTCAACGCACCGAGCACGTGGACGTTCGTCGATATCGAGGGGCCGACTTCGTGAAAGTAGGTACGGAACCAATCGGCGTCTTCGAATTGTAATACGGCTCCGATATCCGGCGACCGTCCAAACTTCGACAAAACATCGTAGGCCACACTTGTGGTGTCACAATCTTCCAAGGTGGAATTTCCTGTCCACCCCACACCTCGACCACGGACCCAATGTTGTTCGACATGGTCAAGATAGGGTAGGTACGTACGAACGATCTCAGGATCGGACAAATCAATATCCGTACGCGAGAGATTCCATAGAGACCAAACAATTTCAAAAATCTCGGCTTGATAGAAGGCCGGCGCACCGCCATCGCCGGCTTGAATTATCGATGAGATGTACGCCAAGGCCCGCTTGTCTCCTGGTTTAACATGTAACGCGAAGTAGGCTGACGCTGATGGCGAATACTTGACCGATCCATTTGTCTCCTGCAAGTTATCGACATCCAACATACCGACACCGTCTTGGCCGGCCAGTTCTACGGAGAAAGCTGCGGTGATATGTTTATTGATTTTGCTTCCGCCGAGTTTTCTCAACTTCTGCTCACGCACTCCGACAAGCTCGCCGAGGATGGATTCCTCGTGGCAAATGGCAAGGCCAAGTCGCGCCGCCTCAGCCATCAGCGTAGGTGCGATTAACTCAAACCCGACGGTTGCGTCTTTTATATCAAGTTGAGGGCCTTCGAAAGCACCCGAGGTAAGGTTCTTCAGGGCTAGCAAGCCTTTTTCAACTTGCGCTGCGCGCCTCCGACGATGCTTATTCGACGTGAGGCTGATCATGGCCGCCAAAGTGGAGAGCAGTCGATCTTCGTAGCAGAAAGGGAACTCGGCTCCCCATGAGCCGTCAGGAAGCTGGCGCTCGCAAAGCCAGTTGAGGGCGAGGTCGCTTAGCTCATCATCGAGCTGGCCCAGCTTCGCGACCCACGCGGTGTCATAGGCTGTGCTCGAGATGCCGTTGCCTAGTGCCGCTTTCGCTAGCAGAGTCCTGAAAGTCTCCATACCATCAGCCCTCCGCGAACCAGATTCCATCATGAACACAACCCACACCGAAAACTCTGTCAGGCTGGGCTCGATATCTGTTGCGCAGTACATTGAGCTGATCGGCCGACATCGCTGAATAGTCAGGTTTGGGCCGGAAATGACGGAGATAGATATGATCGTACAAGATCCTCCGGAGCGTTGTTTCGGTCATATAGTATGAGGGAGCAACGGTGAAGTATAGACTCGTTTTTCCTGAGCTGAGCAGCGGAAAATCGAAAGTGCTGAAACGCCCAAATCCGATGAACATGTCAGCCTTGTCAACATACTCGCCGTAATAACCTTCGATAATCTCTCTCCGCGTGGGAGGTTTACCATGCGTTTCGTTCCACGAGATAGAAAACTGCGCAACAGACTCAGCCGCATCGTTGCCAAAAACACCGAAGCATAGTCTGTGTTCAGTGTTGGATGACGTAGAGATTGTTAGGTCATCGAATGACTTGACAACGGCTGCCCCTTGCGCGGTCGAAGGCAATCTTTTCTTATAATCACCATAAAAAAGAACGTGGACCTCGTGTTCTTTATAGAACGACAGAATTTCCTCGTCGTTGGCAAGCAAGGCCATCCCTTCGAGCGCCTGTACGATATATCGATCACCACGATCCAGAAGATCGTCGCTAAAGATTGGCGAGATTACTGTTTCGATGCCGTGCTCGAAGAGCATGTTCAGAATACGAATTGATTGACGCAAGGCGGCCTGCTGATAATCGTCGTACTGCGGATTACATTCGAGGTGAAACCAGCGGCGTGTGCCATCGAAGGGAAAGACGGATACCTTCGGTCCACGGCAACGTACAATCTCTGCTACGGATACTAGAGGAAGATCCAAGAATTCTTTTTCGCTAACCAAGTTCATGCTTCCTCTTAATAACTATCGCCGGAATCAGGATGGTCTTCGGGTCCAGGGACTTCATGTAGTGCGTTAAGTAGTGATTTGCATCTTATGCGGATTGCGGGGCCGGTGAGTCCGTGGCTGGAAAGGATGTGGTCGCGGCTGGCGTGGGGAATGTAGGCCGGTGGCAGTCCCAGTGTGTAGGTGCGCGTCCGCGGGTGTGTCCGCCCGATGTGGTGGCTAAGGTGCGCGCCGATTCCCACGTCGGCAATCGCATCTTCGACACACACGGTGATCCGATGGCGGCCAGCCAGCTCGGTCAGTGCCGGGCTGATTGGCCAGACCCATTGTGGATCAACGACTGTCACCCCGATCTGCTCCTCGCTGAGGCACCGGGCGGCGTCCATGCATGGTCGACTCATGGCACCCACTGCGACCAAGAGCACGTCGGGTCGCCAATGCGGTGGTGGTGTATGCAAGACGTCGAGGCCACCGATGGTGTGTTCGGCCGTGATCGGTTCGCCCGGCGCCCCTTTGGGGAAACGCACGGCGGTGGGAGCCGCGGTCGCGATCGCGGTACGCAACTGTTGTCGTAGCCGAGGCGCGTCGCGCGGACAGGCGATCTGAAACCCGGGCACGCAGGCCAGCAGCGCCAGATCCCACAAACCGTGATGGCTGGGTCCGTCGGGCCCGGTTACCCCAGCCCGGTCCAGCACCAGCGTCACGGGTAACCGGTGCAGCCCGATGTCGAACAGAAGTTGGTCAAAGGCGCGGTGCAGAAACGTCGAGTACACCGCGACAACGGGATGGGTTCCCGCGGCAGCTAGCCCGGCCGCGCTGGCCAACAGGTGTTGTTCGGCGATGCCCGAATCGAACACCCGATGCGGGTATCGCCTCGACAGCGCGCCTAGACCAGTGGGCAGACGCATCGCCGCGGTCAGCCCGACGACGTCGGATCGGTCGTCAGCAATGCGCGCGATTTCGTCCTCGAACACGTCGGTCCAGCTCCGCTGACTGGGTGTGCTAGCGAGGCCGGTGGCAATGTCGACCACCCCGCAGGCGTGCATATGGTCCCTCTCGTCAGCTTCGGCTGGAGGATAACCCCGGCCCTTACTAGTCACTGCGTGAACAACAACGGGCCTAGCTGCCGCGGCCGCTTTTCGTAGAACCGCGCACGTGTCGGGGATGTTGTGCCCATCGACCGGACCGATGTAGGTAAATCCCATGTTCTCAAAGAGGTTCGGCCCTCGGGGTGTGCCGACGCGAAGTTCTTCTAGGTGTGCCGCAAGAGCCCCAGCGGTGGGGTCGTAGGAGCGGCCATTGTCATTGAGCACGACGATCACGGGCCGGGTAGCGGCACCGAGGTTGTTCAGGCCCTCCCATGCCACGCCCCCGGTGAGGGCGCCATCACCGATCACCGCGATGACACGTCGGTCGCATTGCCCCTGCAGGGCCAATGCTTTGGCGATGCCGTCCACCCAGGCGAGGCTGACCGAGGCATGGGAGTTCTCGACCCAGTCATGTGGCGATTCATGGCGGTTGGGATACCCCGATAGACCATCGGCCTGGCGCAGCGTGGCGAAGTCTTTACCGCGGCCGGTGAGCAGCTTGTGCGGATAGGTTTGGTGCCCGGTGTCGAACACCACGATGTCGTGTGGCGAGGTGAACACCCGATGCAATGCGATGGTCAGCTCTACCATGCCAAGTCCCGCGCCGAGATGGCCACCGGTAGCCGTCACTGTTTCTATGAGCCGCCGACGCATCTGCACGGCCAGCTCTGGCAGCTGGCTTTCGGGCAATGCCTGCACATCGCAAGGTCCGCCGATCGCGGTAATCAAGTCCCCGCGTCCGTTGCGAATCGTGGTTGTCATTGCGCGCGAACCTGTTTGGGAAGGCCGAATCGCACCGTCTCGGTCGCTATCGAGCGTTCCACCACGGTGATCGAGGCGTATCCGCGAAGTGCATCAATCACCTGCCCCACCAGTCGTGGCGGCGCGGAGGCTCCCGCGGTGACACCGATCGTCGAGACCGACGACAGCCATTCGGGCTCAATGTCATCAGGCCCGTCAATCAAGTAGGCCGGCGTCCCACTTCGCTGCGCCAACTCGACCAGACGCCGCGAATTCGACGAATTGCACGAGCCAATCACCAACACAACGTCACATTCACCGACCATCGATTGCAGCGCACGCTGTCTGTTCGTGGTGGCATAGCAGATGTCTTCAGAGGGGGGTTGGCCCAACGTCGGAAACCTCGCGCGCAGCGCATCAATGACATCGGCAGTTTCATCAAGTGCCAGGGTTGTCTGGGTCAGATACGATAGCTGGGTACCCTCGGGCAGGTTCAACGCTGCCACATCAGCGGGTGTCTGCACCAATAATGTTGACCGCGGAGCGACGCCAAGCGTGCCTTCGGTCTCCTCATGTCCGGCGTGCCCGATGAAGACCACCGTGTCACCGCGCGCGGCAAACCGTGCGGCTTCAGCGTGGACTTTCGCCACCAGTGGGCAGGTCGCGTCGACGACCTGCAGTCCCCGCTCATCAGCGCCCGCGCGCACCGCCGGGGAAACCCCATGCGCGGAGAACACCACGACCGCCCCCGGCGGCGGCGGATCGGGAATCTCGTCGAGATCCTCGACGAACACTGCTCCCCGGTCCCGCAACTCGGCAACCACAACAGTGTTGTGCACGATTTGCTTGCGCACATACACCGGGCCTTCGGCCACGTCAAGCACTCGCTTGACCGTCTCGATAGCACGCTCTACACCGGCGCAAAACGACCGCGGCGACGCCAACAGCACCGTGACTTCACCCGAAGCGTATCCCTGTGCGACCGGTCCCACGAACACCTCAGCCATCAGCACTCCCGGCGACATATCAGTTGCGACAACGCGATCAGGTCTGGGGATCGCACCGCATCGGGCAGTGCCGCAATAGCAGCCTGGATGCGTTCATCGGCGCATCGCTGCGCCACATGACCACCCCCGGCCACCTTGACAAGCGCGGTAGCCCGCTCGACATCGCTTGCTGTCATTGCGGCAGGTGCTTGATAGAGGGCCGCCAATTCGGTCGCCGCTTCGGATCGCGAGTTCAGGGCGGCAACAACTGGCAGTGTCGCCTTACGTCGGGCAAGGTCGTTGCCGACCGGCTTTCCCGTCACACCAGGGTCACCCCAGATGCCGATCAGATCGTCGACGCATTGAAACGCAAGACCCAACTCATGGCCAAAACGCTCCAACGCAGCAATCTGAACCGCCCCGGCATGTCCGGAGACTCCAGTTCTTGGAAAGGATGGGGTCATGTCAGGTGGTTCATCGAGGAGGTACCCGCCGGAGCTGCGTGAGCGGGCGGTGCGGATGGTCGCAGAGATCCGCGGTCAGCACGATTCGGAGTGGGCAGCGATCAGTGAGGTCGCCCGTCTACTTGGTGTTGGCTGCGCGGAGACGGTGCGTAAGTGGGTGCGCCAGGCGCAGGTCGATGCCGGCGCACGGCCCGGGACCACGACCGAAGAATCCGCTGAGCTGAAGCGCTTGCGGCGGGACAACGCCGAATTGCGAAGGGCGAACGCGATTTTAAAGACCGCGTCGGCTTTCTTCGCGGCCGAGCTCGACCGGCCAGCACGCTAATTACCCGGTTCATCGCCGATCATCAGGGCCACCGCGAGGGCCCCGATGGTTTGCGGTGGGGTGTCGAGTCGATCTGCACACAGCTGACCGAGCTGGGTGTGCCGATCGCCCCATCGACCTACTACGACCACATCAACCGGGAGCCCAGCCGCCGCGAGCTGCGCGATGGCGAACTCAAGGAGCACATCAGCCGCGTCCACGCCGCCAACTACGGTGTTTACGGTGCCCGCAAAGTGTGGCTAACCCTGAACCGTGAGGGCATCGAGGTGGCCAGATGCACCGTCGAACGGCTGATGACCAAACTCGGCCTGTCCGGGACCACCCGCGGCAAAGCCCGCAGGACCACGATCGCTGATCCGGCCACAGCCCGTCCCGCCGATCTCGTCCAGCGCCGCTTCGGACCACCAGCACCTAACCGGCTGTGGGTAGCAGACCTCACCTATGTGTCGACCTGGGCAGGGTTCGCCTACGTGGCCTTTGTCACCGACGCCTACGCTCGCAGGATCCTGGGCTGGCGGGTCGCTTCCACGATGGCCACCTCCATGGTCCTCGACGCGATCGAGCAAGCCATCTGGACCCGCCAACAAGAAGGCGTACTCGACCTGAAAGACGTTATCCACCATACGGATAGGGGATCTCAGTACACATCGATCCGGTTCAGCGAGCGGCTCGCCGAGGCAGGCATCCAACCGTCGGTCGGAGCGGTCGGAAGCTCCTATGACAATGCACTAGCCGAGACGATCAACGGCCTATACAAGACCGAGCTGATCAAACCCGGCAAGCCCTGGCGGTCCATCGAGGATGTCGAGTTGGCCACCGCGCGCTGGGTCGACTGGTTCAACCATCGCCGCCTCTACCAGTACTGCGGCGACGTCCCGCCGGTCGAACTCGAGGCTGCCTACTACGCTCAACGCCAGAGACCAGCCGCCGGCTG

Protein sequences of DBSCAN-SWA_2

>NC_021251|3706703:3796139|3784669_3785845_+|WP_003417892.1|DBSCAN-SWA
MRKLGPVTIDPRRHDAVLFDTTLDATQELVRQLQEVGVGTGVFGSGLDVPIVAAGRLAVRPGRCVVVSAHSAGVTAARESGFALIIGVDRTGCRDALRRDGADTVVTDLSEVSVRTGDRRMSQLPDALQALGLADGLVARQPAVFFDFDGTLSDIVEDPDAAWLAPGALEALQKLAARCPIAVLSGRDLADVTQRVGLPGIWYAGSHGFELTAPDGTHHQNDAAAAAIPVLKQAAAELRQQLGPFPGVVVEHKRFGVAVHYRNAARDRVGEVAAAVRTAEQRHALRVTTGREVIELRPDVDWDKGKTLLWVLDHLPHSGSAPLVPIYLGDDITDEDAFDVVGPHGVPIVVRHTDDGDRATAALFALDSPARVAEFTDRLARQLREAPLRAT
>NC_021251|3706703:3796139|3778690_3779335_-|WP_003417881.1|DBSCAN-SWA
MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNSQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRGERMGRVRDSATYLAEHMHRAPVLLIPCLKGREDESAVGGVSFWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLPIAYTQGIDFRPAKRLPAESVTHWNGW
>NC_021251|3706703:3796139|3786081_3786723_+|WP_003900037.1|DBSCAN-SWA
MRRRAMTKMDEASNPCGGDIEAEMCQLMREQPPAEGVVDRVALQRHRNVALITLSHPQAQNALNLASWRRLKRLLDDLAGESGLRAVVLRGAGDKAFAAGADIKEFPNTRMSAADAAEYNESLAVCLRALTTMPIPVIAAVRGLAVGGGCELATACDVCIATDDARFGIPLGKLGVTTGFTEADTVARLIGPAALKYLLFSGELIGIEEAARW
>NC_021251|3706703:3796139|3720425_3721058_+|WP_009940431.1|DBSCAN-SWA
MLADHVERQLDELGWETSHIVGNSLGGWVAFELERRGRARSVTGIAPAGGWTRWSPVKFEVIAKFIAGAPILAVAHILGQRALRLPFSRLLATLPISATPDGVSERELSGIIDDAAHCPAYFQLLVKALVLPGLQELEHTAVPSHVVLCEQDRVVPPSRFSRHFTDSLPAGHRLTVLDGVGHVPMFEAPGRITELITSFIEECCPHVRAS
>NC_021251|3706703:3796139|3710850_3712218_+|WP_003902446.1|DBSCAN-SWA
MPEPSAALANTTTRNLWLHFARHGAGIQHPVIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIELAERLARYAPGDLNRVFFTSGGTEAVETAWKVAKQYFKLTGKPGKHKVISRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPNTNFYRAPLHTDLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERVREICDRYDVLLVSDEVICAFGRIGSMFACEDLGYVPDMITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFEREGLSDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTDDERARLLGQVSAALFEAGLYCRTDDRGDPVVQVAPPLISGQPEFDTIETILRSVLTDTGRKYLHL
>NC_021251|3706703:3796139|3779856_3783096_-|WP_003908228.1|DBSCAN-SWA
MERVLNGKPRHAGVPAFDADGDVPRSRKRGAYQPPGRERVGSSVAYAELHAHSAYSFLDGASTPEELVEEAARLGLCALALTDHDGLYGAVRFAEAAAELDVRTVFGAELSLGATARTERPDPPGPHLLVLARGPEGYRRLSRQLAAAHLAGGEKGKPRYDFDALTEAAGGHWHILTGCRKGHVRQALSQGGPAAAQRALADLVDRFTPSRVSIELTHHGHPLDDERNAALAGLAPRFGVGIVATTGAHFADPSRGRLAMAMAAIRARRSLDSAAGWLAPLGGAHLRSGEEMARLFAWCPEAVTAAAELGERCAFGLQLIAPRLPPFDVPDGHTEDSWLRSLVMAGARERYGPPKSAPRAYSQIEHELKVIAQLRFPGYFLVVHDITRFCRDNDILCQGRGSAANSAVCYALGVTAVDPVANELLFERFLSPARDGPPDIDIDIESDQREKVIQYVYHKYGRDYAAQVANVITYRGRSAVRDMARALGFSPGQQDAWSKQVSHWTGQADDVDGIPEQVIDLATQIRNLPRHLGIHSGGMVICDRPIADVCPVEWARMANRSVLQWDKDDCAAIGLVKFDLLGLGMLSALHYAKDLVAEHKGIEVDLARLDLSEPAVYEMLARADSVGVFQVESRAQMATLPRLKPRVFYDLVVEVALIRPGPIQGGSVHPYIRRRNGVDPVIYEHPSMAPALRKTLGVPLFQEQLMQLAVDCAGFSAAEADQLRRAMGSKRSTERMRRLRGRFYDGMRALHGAPDEVIDRIYEKLEAFANFGFPESHALSFASLVFYSAWFKLHHPAAFCAALLRAQPMGFYSPQSLVADARRHGVAVHGPCVNASLAHATCENAGTEVRLGLGAVRYLGAELAEKLVAERTANGPFTSLPDLTSRVQLSVPQVEALATAGALGCFGMSRREALWAAGAAATGRPDRLPGVGSSSHIPALPGMSELELAAADVWATGVSPDSYPTQFLRADLDAMGVLPAERLGSVSDGDRVLIAGAVTHRQRPATAQGVTFINLEDETGMVNVLCTPGVWARHRKLAHTAPALLIRGQVQNASGAITVVAERMGRLTLAVGARSRDFR
>NC_021251|3706703:3796139|3741545_3741803_-|WP_003417619.1|DBSCAN-SWA
MTVRAVLRRTVGAQWPILAGVNFWRRGALLIGIGVGVAAVLRLVLSEERAGLLVVRSKGIDFVTTVTVAAAMVYIASTIDPLGTG
>NC_021251|3706703:3796139|3786723_3786972_+|WP_003417897.1|DBSCAN-SWA
MVQKVVAPQDLAAATAKLVGQVCRQSAVTMRAAKVVANMHGRALTGADTDALIRFGVEAYEGADLREGVAAFSQGRPPKFDD
>NC_021251|3706703:3796139|3708441_3709971_+|WP_003902445.1|transposase|DBSCAN-SWA
MSARLERDLLAAGQQVVRVPTKLMAQTRKSARSRGKSDPIDALAVARAVLRETDLPLATHDETSRELKLLTDRRDVLVAQRTSAINRLRWLVHELDPERAPAARSLDAAKHQQALRTWLDTQPGLVAELARAELTDIIRLTGEINTLAQRISARVHQVAPALLEIPGCAELTAAKIVGEAAGVTRFKSEAAFACHAAVAPIPVWSGNTAGQMRLSRSGNRQLNAALHRIALTQIRMTDSRGQAYYQRLQDAGKTKRAALRCLKRRLARTVFQALRTVHQPSSEHTQPAAACHRSYCSSHLGEPPRLTDMTQKTRIQPLPPKRAGLLIRALYRIAKRRFGEVPEPFTVTAHHRRLLIANVVHEALLQRASRKLPPSVRELAVFWTARSIGCSWCVDFGAMLQRLDGLDVDRLTDIDNYATSSKFSDDERAAIAYAEAMTADPHSVTDEQVADLRARFGEAGVIELTYQIGVENMRARMNSALGITEQGFNSGDACRVPWAAPDVPSAESR
>NC_021251|3706703:3796139|3718240_3719110_-|WP_003417435.1|DBSCAN-SWA
MGELAEPGVLDRLRARFGWLDHVVRAFTRFNDRNGSLFAAGLTYYTIFAIFPLLMVGFGVGGFALSRRPELLTTLEERIRTSVSGAVGQQLVDLMNSAIDARASVGVIGLATAAWVGLGWMWHLREALSQMWAHPVAPAGYLRTKLSDLAAMVGTFVVIVATIALTVLGHARPMAAVLRWLEIPQFSVFDEIFRGISVLVSVLVSWVLFTWMIGRLPREPVGLVTAARAGLMAAVGFELFKQVGAIYLQIVLRSPAGAVFGPVLGLMVFAFVTAWLILFATAWAATASA
>NC_021251|3706703:3796139|3779333_3779768_+|WP_003417882.1|DBSCAN-SWA
MWAGYRWAMSVELTQEVSARLTSDLYGWLTTVARSGQPVPRLVWFYFDGTDLTVYSMPQAAKVAHITAHPQVSLNLDSDGNGAGIIVVGGTAAVVATDVDCRDDAPYWAKYREDAAKFGLTEAIAAYSTRLKITPTRVWTTPTG
>NC_021251|3706703:3796139|3725133_3725865_+|WP_003417461.1|DBSCAN-SWA
MTCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAALPQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRVTLPEPFTTVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRATLA
>NC_021251|3706703:3796139|3765692_3766487_-|WP_003417738.1|DBSCAN-SWA
MLASCPARSGAAVADAIKSAVGVQPSGVEHKTLRRMDLVRYLAGGHTTYPPEGFVAGSDVIGTTNPAAAQAIVAAIGTWPPAAGRASALIDSLGGAVGDMDPEGSAFPWCRQSAVVQWYVNTPSDGQVATANKWLSDAHHAVQHFSVGGYVNYLEANAAASQYFGANLSRLTTVRRKYDPDRIMYSGLDFSTRQVAERLLPALGFRVRFGVLVIRCALCTDTVKRLGTLPNLTWSRLKVNVAVTQEQAGVMDLPALPVRRTPRR
>NC_021251|3706703:3796139|3716446_3717292_-|WP_003417421.1|DBSCAN-SWA
MFTGIASHAGALGAALVVLIGAAILHDGPAAADPNQDDRFLALLEKKEIPAVANVPRVIDAAHKVCRKLDGGMPVNDIVDGLRNDAYNIDPVMRLYPVRLTTTMTRFISAAVEIYCPNHHSKMAFAMANFEPGSNEPTHRVAASTRSAVNSGSDLRASVSDMTIMSPGWREPTGAMLASVLGAVRAGDPLIPNPPPIPVPPPAAQTLIPPPPIVAPPPPRPAPPQQPPPPPPEVEPPAGVPQSGGAAGSGGAGSGGGGGGDGPVEPSPARPMPPGFIRLAP
>NC_021251|3706703:3796139|3715104_3716256_+|WP_003417418.1|DBSCAN-SWA
MTVLGADAVVIDGRICRPGWVHTADGRILSGGAGAPPMPADAEFPDAIVVPGFVDMHVHGGGGASFADGNAADIARAAEFHLRHGTTTTLASLVTAGPAELLSAVGALAEATRDGVVAGIHLEGPWLSPARCGAHDHTRMRAPDPAEIESVLAAADGAVRMVTLAPELPGSDAAIRRFRDAEVVVAVGHTDATYTQTRHAIDLGATVGTHLFNAMPPLDHRAPGPVLALLCDPRVTVEIIADGVHVHPAVVHAVIEAVGPDRVAVVTDAIAAAGCGDGAFRLGTMPIEVESSVARVAGASTLAGSTTTMDQLFRTVAGLGSKSDSAGDVALAAAVQVTSATPARALGLTGVGRLAAGYAANLVVLDRDLRVTAVMVNDDWRVG
>NC_021251|3706703:3796139|3753675_3753963_-|WP_009938650.1|DBSCAN-SWA
MSRRRRRARRAGVVSISVKEYAVTSPKDLPYGEDRIMVRWNKIRWRCREDYCKLGPFTEAITQVPARVRSTLRLRRQMAKAIGDAARSVGRGRPG
>NC_021251|3706703:3796139|3794878_3796139_+|WP_087902221.1|transposase|DBSCAN-SWA
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_021251|3706703:3796139|3786976_3788404_+|WP_014585402.1|DBSCAN-SWA
MTDADSAVPPRLDEDAISKLELTEVADLIRTRQLTSAEVTESTLRRIERLDPQLKSYAFVMPETALAAARAADADIARGHYEGVLHGVPIGVKDLCYTVDAPTAAGTTIFRDFRPAYDATVVARLRAAGAVIIGKLAMTEGAYLGYHPSLPTPVNPWDPTAWAGVSSSGCGVATAAGLCFGSIGSDTGGSIRFPTSMCGVTGIKPTWGRVSRHGVVELAASYDHVGPITRSAHDAAVLLSVIAGSDIHDPSCSAEPVPDYAADLALTRIPRVGVDWSQTTSFDEDTTAMLADVVKTLDDIGWPVIDVKLPALAPMVAAFGKMRAVETAIAHADTYPARADEYGPIMRAMIDAGHRLAAVEYQTLTERRLEFTRSLRRVFHDVDILLMPSAGIASPTLETMRGLGQDPELTARLAMPTAPFNVSGNPAICLPAGTTARGTPLGVQFIGREFDEHVLVRAGHAFQQVTGYHRRRPPV
>NC_021251|3706703:3796139|3719130_3720141_-|WP_003417440.1|tRNA|DBSCAN-SWA
MSTPTGSRRIFSGVQPTSDSLHLGNALGAVAQWVGLQDDHDAFFCVVDLHAITIPQDPEALRRRTLITAAQYLALGIDPGRATIFVQSQVPAHTQLAWVLGCFTGFGQASRMTQFKDKSARQGSEATTVGLFTYPVLQAADVLAYDTELVPVGEDQRQHLELARDVAQRFNSRFPGTLVVPDVLIPKMTAKIYDLQDPTSKMSKSAGTDAGLINLLDDPALSAKKIRSAVTDSERDIRYDPDVKPGVSNLLNIQSAVTGTDIDVLVDGYAGHGYGDLKKDTAEAVVEFVNPIQARVDELTADPAELEAVLAAGAQRAHDVASKTVQRVYDRLGFLL
>NC_021251|3706703:3796139|3769119_3769395_+|WP_003417757.1|DBSCAN-SWA
MSISASEARQRLFPLIEQVNTDHQPVRITSRAGDAVLMSADDYDAWQETVYLLRSPENARRLMEAVARDKAGHSAFTKSVDELREMAGGEE
>NC_021251|3706703:3796139|3772482_3772851_-|WP_003417772.1|DBSCAN-SWA
MFNPAGDRPKAGLVRPYTLTAGRTGTDVDLPLQAPVQTLPAGPAGRWPAYDMRRRILQLCIGSPSVAEISARLDLPVGVARVLVGDLVTSGYLRVHATLTDRSTRDERHELIGRTLRGLKAL
>NC_021251|3706703:3796139|3771920_3772502_-|WP_003417769.1|DBSCAN-SWA
MALKHSEASGTASTKIVIAGGFGSGKTTFVGAVSEIMPLRTEAMVTDASAGVDMLEATPDKRSTTVAMDFGRITLGEDLVLYLFGTPGQRRFWFMWDDLVRGAIGAIVLVDCRRLQDSFAAVDFFEHRNLPFLIAINEFDSAPRYPVSAVRDALTLPAHIPVINVDARNRRSATDALIAVSEYALATLSPAGG
>NC_021251|3706703:3796139|3770997_3771366_+|WP_003417765.1|DBSCAN-SWA
MSRPHPPVLTVRSDRSQQCFAAGRDVVVGSDLRADMRVAHPLIARAHLLLRFDRGNWIAIDNDSQSGMFVDGQRVSEVDIYDGLTINIGKPTGPWITFEVGHHQGIIGRLSRTPSSRPGSPI
>NC_021251|3706703:3796139|3776914_3778690_+|WP_009938654.1|DBSCAN-SWA
MSFVVAVPEALAAAASDVANIGSALSAANAAAAAGTTGLLAAGADEVSAALASLFSGHAVSYQQVAAQATALHDQFVQALTGAGGSYALTEAANVQQNLLNAINAPTQALLGRPLIGDGAVGTASSPDGQDGGLLFGNGGAGYNSAATPGMAGGNGGNAGLIGNGGTGGSGGAGAAGGAGGSGGWLYGNGGNGGIGGNAIVAGGAGGNGGAGGAAGLWGSGGSGGQGGNGLTGNDGVNPAPVTNPALNGAAGDSNIEPQTSVLIGTQGGDGTPGGAGVNGGNGGAGGDANGNPANTSIANAGAGGNGAAGGDGGANGGAGGAGGQAASAGSSVGGDGGNGGAGGTGTNGHAGGAGGAGGAGGRGGWLVGNGGNGGNGGNGAAGGNGAIGGTGGAGGVPANQGGNSALGTQPVGGDGGDGGNGGTGGTGGRGGDGGSGGAGGASGWLMGNGGNGGNGGTGGSGGVGGNGGIGGDGAGGGNATSTSSIPFDAHGGNGGAGGDAGHGGTGGDGGDGGHAGTGGRGGLLAGQHANSGNGGGGGTGGAGGTHGTPGSGNAGGTGTGNADSTNGGPGSDGLGGDAFNGSRGTDGNPG
>NC_021251|3706703:3796139|3768150_3768996_-|WP_003417751.1|DBSCAN-SWA
MGAIMLDGKATRDEIFGDLKQRVAALDAAGRTPGLGTILVGDDPGSQAYVRGKHADCAKVGITSIRRDLPADISTATLNETIDELNANPDCTGYIVQLPLPKHLDENAALERVDPAKDADGLHPTNLGRLVLGTPAPLPCTPRGIVHLLRRYDISIAGAHVVVIGRGVTVGRPLGLLLTRRSENATVTLCHTGTRDLPALTRQADIVVAAVGVAHLLTADMVRPGAAVIDVGVSRTDDGLVGDVHPDVWELAGHVSPNPGGVGPLTRAFLLTNVVELAERR
>NC_021251|3706703:3796139|3712286_3713504_+|WP_003417415.1|DBSCAN-SWA
MAFLRSVSCLAAAVFAVGTGIGLPTAAGEPNAAPAACPYKVSTPPAVDSSEVPAAGEPPLPLVVPPTPVGGNALGGCGIITAPGSAPAPGDVSAEAWLVADLDSGAVIAARDPHGRHRPASVIKVLVAMASINTLTLNKSVAGTADDAAVEGTKVGVNTGGTYTVNQLLHGLLMHSGNDAAYALARQLGGMPAALEKINLLAAKLGGRDTRVATPSGLDGPGMSTSAYDIGLFYRYAWQNPVFADIVATRTFDFPGHGDHPGYELENDNQLLYNYPGALGGKTGYTDDAGQTFVGAANRDGRRLMTVLLHGTRQPIPPWEQAAHLLDYGFNTPAGTQIGTLIEPDPSLMSTDRNPADRQRVDPQAAARISAADALPVRVGVAVIGALIVFGLIMVARAMNRRPQH
>NC_021251|3706703:3796139|3769391_3769649_+|WP_003417760.1|DBSCAN-SWA
MRSVNFDPDAWEDFLFWLAADRKTARRITRLIGEIQRDPFSGIGKPEPLQGELSGYWSRRIDDEHRLVYRAGDDEVTMLKARYHY
>NC_021251|3706703:3796139|3767082_3767343_-|WP_003417741.1|DBSCAN-SWA
MSRQTFLRGAVGAPATSAVFPTILARATPGDGWASLASSIGGQVLLPANGRAFTSGKQIFNSNYSGLNPAAVVTVASQADVRKAVS
>NC_021251|3706703:3796139|3772828_3773221_-|WP_003417776.1|DBSCAN-SWA
MKARLPDSPLDWLVSKFAREVPGVAHALLVSVDGLPVAASEHLPRERADQLAAVTSGLASLAGGAAQLFDGGQVLQSVVEMQNGYLLLMQVGDGSALAALAATGCDIGQIGYEMAILVERVGGVVQSCRR
>NC_021251|3706703:3796139|3790713_3791604_-|WP_016330438.1|DBSCAN-SWA
MNLVSEKEFLDLPLVSVAEIVRCRGPKVSVFPFDGTRRWFHLECNPQYDDYQQAALRQSIRILNMLFEHGIETVISPIFSDDLLDRGDRYIVQALEGMALLANDEEILSFYKEHEVHVLFYGDYKKRLPSTAQGAAVVKSFDDLTISTSSNTEHRLCFGVFGNDAAESVAQFSISWNETHGKPPTRREIIEGYYGEYVDKADMFIGFGRFSTFDFPLLSSGKTSLYFTVAPSYYMTETTLRRILYDHIYLRHFRPKPDYSAMSADQLNVLRNRYRAQPDRVFGVGCVHDGIWFAEG
>NC_021251|3706703:3796139|3791612_3793451_-|WP_003918607.1|DBSCAN-SWA
MTTTIRNGRGDLITAIGGPCDVQALPESQLPELAVQMRRRLIETVTATGGHLGAGLGMVELTIALHRVFTSPHDIVVFDTGHQTYPHKLLTGRGKDFATLRQADGLSGYPNRHESPHDWVENSHASVSLAWVDGIAKALALQGQCDRRVIAVIGDGALTGGVAWEGLNNLGAATRPVIVVLNDNGRSYDPTAGALAAHLEELRVGTPRGPNLFENMGFTYIGPVDGHNIPDTCAVLRKAAAAARPVVVHAVTSKGRGYPPAEADERDHMHACGVVDIATGLASTPSQRSWTDVFEDEIARIADDRSDVVGLTAAMRLPTGLGALSRRYPHRVFDSGIAEQHLLASAAGLAAAGTHPVVAVYSTFLHRAFDQLLFDIGLHRLPVTLVLDRAGVTGPDGPSHHGLWDLALLACVPGFQIACPRDAPRLRQQLRTAIATAAPTAVRFPKGAPGEPITAEHTIGGLDVLHTPPPHWRPDVLLVAVGAMSRPCMDAARCLSEEQIGVTVVDPQWVWPISPALTELAGRHRITVCVEDAIADVGIGAHLSHHIGRTHPRTRTYTLGLPPAYIPHASRDHILSSHGLTGPAIRIRCKSLLNALHEVPGPEDHPDSGDSY
>NC_021251|3706703:3796139|3717766_3718207_+|WP_003900026.1|DBSCAN-SWA
MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHDRGEAPCAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWILESDLDEPTAIEVSDIHA
>NC_021251|3706703:3796139|3773217_3775848_-|WP_003901616.1|DBSCAN-SWA
MTMFARPTIPVAAAASDISAPAQPARGKPQQRPPSWSPRNWPVRWKVFTIALLPLVVAMVLAGLRVEAAMASTSGLRLVAARAEMIPAITKYMSALDVAVLASSTGHDVEGAQKNFTARKYELQTRLADTDVIADVRSGVNTLLNGGQALLDKVLADSIGLRDRVTAYAPLLLTAQNVIDASVRVDSEQIRTQVQGLSRAVGARGQMTMQEILVTRGADLAEPQLRSAMVTLAGTEPSTLFGMSAALGAGSPDTKNLQQQMVTRMAIMSDPAVALVNNPELLHSIQITRDIAEQVITDTTEAVTKSVQSQATDRRDAAIRDAVLVLAAIATAIVVVLVVARTLVGPMRVLRDGALKVAHTDLDGEIAAVRAGDEPIPEPLAVYTTEEIGQVAHAVDELHTRALLLAGEETRLRLLVNEMFETMSRRSRSLVDQQLSVIDQLERNEEDPARLDSLFRLDHLAARLRRNSANLLVLAGAQITRDHREPVPLSTVISAAVSEVEDYRRVDIARVPDCAVVGAAAGGVIHLLAELIDNALRYSSPTTPVRVAAAIGSEGSVLLRISDSGLGMTDADRRMANMRLRAGGEVTPDSARHMGLFVVGRLAGRHGIRVGLRGPVTGEQGTGTTAEVYLPLAVLEGTAPAQPPKPRVFAIKPPCPEPAAADPTDVPAAIGPLPPVTLLPRRTPGSRGIADVPAQPMRQRRRELKTPWWEDRFQQEPKQPPAPEPRPAPPPAKPAPPAGPVDDDVIYRRMLSEMVGDPHELAHSPDLDWKSVWDHGWSAAAEAADKPVQSRTDYGLPVREPGARLVPGAAVPEGPDREHPGAALASNGGLHPGRAPRHAAAVRDPDAVRASISSHFGGVRTGRSHARESSQGPNQQ
>NC_021251|3706703:3796139|3776083_3776548_+|WP_003901617.1|tRNA|DBSCAN-SWA
MFRLLFVSPRIAPNTGNAIRTCAATGCELHLVEPLGFDLSEPKLRRAGLDYHDLASVTVHASLAHAWEALSPARVFAFTAQATTLFTNVGYHAGDVLMFGPEPTGLDEATLADTHITGQVRIPMLAGRRSLNLSNAAAVAVYEAWRQHGFAGAV
>NC_021251|3706703:3796139|3752157_3752604_+|WP_049961743.1|transposase|DBSCAN-SWA
MDAAITACHHIAIRDDVGARSIRFSVEPTLAGLRTLTDKLSGYDDIDATVEPTSMTWLPLTIAVENAGDTMHMAGARHCARLRGAIVGKSKSDVIDAEVLTRASEVFDLTPLTLPTPAQLALRRSVIRRAGAVIDANRSWRRLMSLAR
>NC_021251|3706703:3796139|3723997_3725137_+|WP_003417458.1|DBSCAN-SWA
MTISDVPTQTLPAEGEIGLIDVGSLQLESGAVIDDVCIAVQRWGKLSPARDNVVVVLHALTGDSHITGPAGPGHPTPGWWDGVAGPGAPIDTTRWCAVATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVQADVAALAALGITEVAAVVGGSMGGARALEWVVGYPDRVRAGLLLAVGARATADQIGTQTTQIAAIKADPDWQSGDYHETGRAPDAGLRLARRFAHLTYRGEIELDTRFANHNQGNEDPTAGGRYAVQSYLEHQGDKLLSRFDAGSYVILTEALNSHDVGRGRGGVSAALRACPVPVVVGGITSDRLYPLRLQQELADLLPGCAGLRVVESVYGHDGFLVETEAVGELIRQTLGLADREGACRR
>NC_021251|3706703:3796139|3793447_3794437_-|WP_003417912.1|DBSCAN-SWA
MAEVFVGPVAQGYASGEVTVLLASPRSFCAGVERAIETVKRVLDVAEGPVYVRKQIVHNTVVVAELRDRGAVFVEDLDEIPDPPPPGAVVVFSAHGVSPAVRAGADERGLQVVDATCPLVAKVHAEAARFAARGDTVVFIGHAGHEETEGTLGVAPRSTLLVQTPADVAALNLPEGTQLSYLTQTTLALDETADVIDALRARFPTLGQPPSEDICYATTNRQRALQSMVGECDVVLVIGSCNSSNSRRLVELAQRSGTPAYLIDGPDDIEPEWLSSVSTIGVTAGASAPPRLVGQVIDALRGYASITVVERSIATETVRFGLPKQVRAQ
>NC_021251|3706703:3796139|3742058_3751532_-|WP_003901612.1|DBSCAN-SWA
MNFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPYAGWLGSVAAQAVAVAGQARAAVAAFEAALAATVDPAAVAVNRMAMRALAMSNLLGQNAAAIAAVEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLNALFAGPAKMLRLNAGLGNVGNYNVGLGNVGIFNLGAANVGAQNLGAANAGSGNFGFGNIGNANFGFGNSGLGLPPGMGNIGLGNAGSSNYGLANLGVGNIGFANTGSNNIGIGLTGDNLTGIGGLNSGTGNLGLFNSGTGNIGFFNSGTGNFGVFNSGSYNTGVGNAGTASTGLFNVGGFNTGVANVGSYNTGSFNAGNTNTGGFNPGNVNTGWLNTGNTNTGIANSGNVNTGAFISGNFSNGVLWRGDYEGLWGLSGGSTIPAIPIGLELNGGVGPITVLPIQILPTIPLNIHQTFSLGPLVVPDIVIPAFGGGTAIPISVGPITISPITLFPAQNFNTTFPVGPFFGLGVVNISGIEIKDLAGNVTLQLGNLNIDTRINQSFPVTVNWSTPAVTIFPNGISIPNNPLALLASASIGTLGFTIPGFTIPAAPLPLTIDIDGQIDGFSTPPITIDRIPLNLGASVTVGPILINGVNIPATPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGSSGWWNQAQTEVAGAGSGFANFGSLGSGVLNFGSGVSGLYNTGGLPPGTPAVVSGIGNVGEQLSGLSSAGTALNQSLIINLGLADVGSVNVGFGNVGDFNLGAANIGDLNVGLGNVGGGNVGFGNIGDANFGLGNAGLAAGLAGVGNIGLGNAGSGNVGFGNMGVGNIGFGNTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNVGLFNSGTGNFGLFNSGGYNTGIGNGGTGSTGLFNAGNFNTGVANPGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGVANSGTVNTGAFITGNDSNGILWRGNFEGLFGLNVGITIPEFPIHWTSTGGIGPIIIPDTTILPPIHLGLTGQANYGFAVPDIPIPAIHIDFDGAADAGFTAPATTLLSALGITGQFRFGPITVSNVQLNPFNVNLKLQFLHDAFPNEFPDPTISVQIQVAIPLTSATLGGLALPLQQTIDAIELPAISFSQSIPIDIPPIDIPASTINGISMSEVVPIDVSVDIPAVTITGTRIDPIPLNFDVLSSAGPINISIIDIPALPGFGNSTELPSSGFFNTGGGGGSGIANFGAGVSGLLNQASSPMVGTLSGLGNAGSLASGVLNSGVDISGMFNVSTLGSAPAVISGFGNLGNHVSGVSIDGLLAMLTSGGSGGSGQPSIIDAAIAELRHLNPLNIVNLGNVGSYNLGFANVGDVNLGAGNLGNLNLGGGNLGGQNLGLGNLGDGNVGFGNLGHGNVGFGNSGLGALPGIGNIGLGNAGSNNVGFGNMGLGNIGFGNTGTNNLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTGNIGFFNTGTGNWGLFNSGSYNTGIGNSGTGSTGLFNAGSFNTGLANAGSYNTGSLNAGNTNTGGFNPGNVNTGWFNAGHTNTGGFNTGNVNTGAFNSGSFNNGALWTGDHHGLVGFSYSIEITGSTLVDINETLNLGPVHIDQIDIPGMSLFDIHELVNIGPFRIEPIDVPAVVLDIHETMVIPPIVFLPSMTIGGQTYTIPLDTPPAPAPPPFRLPLLFVNALGDNWIVGASNSTGMSGGFVTAPTQGILIHTGPSSATTGSLALTLPTVTIPTITTSPIPLKIDVSGGLPAFTLFPGGLNIPQNAIPLTIDASGVLDPITIFPGGFTIDPLPLSLALNISVPDSSVPIIIVPPTPGFGNATATPSSGFFNSGAGGVSGFGNFGAGSSGWWNQAHAALAGAGSGVLNVGTLNSGVLNVGSGISGLYNTAIVGLGTPALVSGAGNVGQQLSGVLAAGTALTQSPIINLGLADVGNYNLGLGNVGDFNLGAANLGDLNLGLGNIGNANVGFGNIGHGNVGFGNSGLGAALGIGNIGLGNAGSTNVGLANMGVGNIGFANTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNIGFFNSGTGNWGLFNSGSFNTGIGNSGTGSTGLFNAGGFTTGLANAGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGIANSGNVDTGALMSGNFSNGILWRGNYEGLFSYSYSLDVPRITILDAHFTGAFGPVVVPPIPVPAINAHLTGNAAMGAFTIPQIDIPALNPNVTGSVGFGPIAVPSVTIPALTAARAVLDMAASVGATSEIEPFIVWTSSGAIGPTWYSVGRIYNAGDLFVGGNIISGIPTLSTTGPVHAVFNAASQAFNTPALNIHQIPLGFQVPGSIDAITLFPGGLTFPANSLLNLDVFVGTPGATIPAITFPEIPANADGELYVIAGDIPLINIPPTPGIGNTTTVPSSGFFNTGAGGGSGFGNFGANMSGWWNQAHTALAGAGSGIANVGTLHSGVLNLGSGLSGIYNTSTLPLGTPALVSGLGNVGDHLSGLLASNVGQNPITIVNIGLANVGNGNVGLGNIGNLNLGAANIGDVNLGFGNIGDVNLGFGNIGGGNVGFGNIGDANFGFGNSGLAAGLAGMGNIGLGNAGSGNVGWANMGLGNIGFGNTGTNNLGIGLTGDNQSGIGGLNSGTGNIGLFNSGTGNIGFFNSGTANFGLFNSGSYNTGIGNSGVASTGLVNAGGFNTGVANAGSYNTGSFNAGDTNTGGFNPGSTNTGWFNTGNANTGVANAGNVNTGALITGNFSNGILWRGNYEGLAGFSFGYPIPLFPAVGADVTGDIGPATIIPPIHIPSIPLGFAAIGHIGPISIPNIAIPSIHLGIDPTFDVGPITVDPITLTIPGLSLDAAVSEIRMTSGSSSGFKVRPSFSFFAVGPDGMPGGEVSILQPFTVAPINLNPTTLHFPGFTIPTGPIHIGLPLSLTIPGFTIPGGTLIPQLPLGLGLSGGTPPFDLPTVVIDRIPVELHASTTIGPVSLPIFGFGGAPGFGNDTTAPSSGFFNTGGGGGSGFSNSGSGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGTLGLVTSAFVSGFMNVGQQLSGLLFAGTGP
>NC_021251|3706703:3796139|3722636_3723986_+|WP_003900028.1|DBSCAN-SWA
MSADSNSTDADPTAHWSFETKQIHAGQHPDPTTNARALPIYATTSYTFDDTAHAAALFGLEIPGNIYTRIGNPTTDVVEQRIAALEGGVAALFLSSGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYSLAKLGIEVSFVDDPDDLDTWQAAVRPNTKAFFAETISNPQIDLLDTPAVSEVAHRNGVPLIVDNTIATPYLIQPLAQGADIVVHSATKYLGGHGAAIAGVIVDGGNFDWTQGRFPGFTTPDPSYHGVVFAELGPPAFALKARVQLLRDYGSAASPFNAFLVAQGLETLSLRIERHVANAQRVAEFLAARDDVLSVNYAGLPSSPWHERAKRLAPKGTGAVLSFELAGGIEAGKAFVNALKLHSHVANIGDVRSLVIHPASTTHAQLSPAEQLATGVSPGLVRLAVGIEGIDDILADLELGFAAARRFSADPQSVAAF
>NC_021251|3706703:3796139|3725873_3735215_-|WP_038438875.1|DBSCAN-SWA
MSFVVMPPEINSLLIYTGAGPGPLLAAAAAWDELAAELGSAAAAFGSVTSGLVGGIWQGPSSVAMAAAAAPYAGWLSAAAASAESAAGQARAVVGVFEAALAATVDPFVIAANRSRLVSLALSNLFGQNTPAIAAAEFDYELMWAQDVAAMLGYHTGASAAAEALAPFGSPLASLAAAAEPAKSLAVNLGLANVGLFNAGSGNVGSYNVGAGNVGSYNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGEANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGVLWRGDYQGLLGFSSGANVLPVIPLSLDINGGVGAITIEPIHILPDIPININETLYLGPLVVPPINVPAISLGVGIPNISIGPIKINPITLWPAQNFNQTITLAWPVSSITIPQIQQVALSPSPIPTTLIGPIHINTGFSIPVTFSYSTPALTLFPVGLSIPTGGPLTLTLGVTAGTEAFTIPGFSIPEQPLPLAINVIGHINALSTPAITIDNIPLNLHAIGGVGPVDIVGGNVPASPGFGNSTTAPSSGFFNTGAGGVSGFGNVGAHTSGWFNQSTQAMQVLPGTVSGYFNSGTLMSGIGNVGTQLSGMLSGGALGGNNFGLGNIGFDNVGFGNAGSSNFGLANMGIGNIGLANTGNGNIGIGLSGDNLTGFGGFNSGSENVGLFNSGTGNVGFFNSGTGNLGVFNSGSHNTGFFLTGNNINVLAPFTPGTLFTISEIPIDLQVIGGIGPIHVQPIDIPAFDIQITGGFIGIREFTLPEITIPAIPIHVTGTVGLEGFHVNPAFVLFGQTAMAEITADPVVLPDPFITIDHYGPPLGPPGAKFPSGSFYLSISDLQINGPIIGSYGGPGTIPGPFGATFNLSTSSLALFPAGLTVPDQTPVTVNLTGGLDSITLFPGGLAFPENPVVSLTNFSVGTGGFTVFPQGFTVDRIPVDLHTTLSIGPFPFRWDYIPPTPANGPIPAVPGGFGLTSGLFPFHFTLNGGIGPISIPTTTVVDALNPLLTVTGNLEVGPFTVPDIPIPAINFGLDGNVNVSFNAPATTLLSGLGITGSIDISGIQITNIQTQPAQLFMSVGQTLFLFDFRDGIELNPIVIPGSSIPITMAGLSIPLPTVSESIPLNFSFGSPASTVKSMILHEILPIDVSINLEDAVFIPATVLPAIPLNVDVTIPVGPINIPIITEPGSGNSTTTTSDPFSGLAVPGLGVGLLGLFDGSIANNLISGFNSAVGIVGPNVGLSNLGGGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGFGNVGLANSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNIGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIVSTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLDFSFPVGPLIPQTHLVHLRETVNLGPIHIDPIHVHIPPLLDIDQTIDLGSFTVAPITVAPIALDYHETFDLGPLVIFPPMNIPATVIESFSTAPGGPAPPPFVIPATSNVFISTVDFATGNNVIGPFSGALAPTTIQLGASGPSFSVLNLSIPPIHIPGLTIPSVPLRIDVDGGIPGFTLFPDGLTFPKIPVHVDAFAGIPDFTIFPNGYTIDPIPLQLNLDLTLGPVHILIDLPAVPGFGNTTGAPSSGFFNSGAGGVSGFGNVGAMVSGGWNQAPSALLGGGSGVFNAGTLHSGVLNFGSGMSGLFNTSVLGLGAPALVSGLGSVGQQLSGLLASGTALHQGLVLNFGLADVGLGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIVSTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYRPAVLPQTPFLDLTLTGGLGSVVIPAIDIPAIRPEFSANVAIDSFTVPSIPIPQIDLAATTVSVGLGPITVPHLDIPRVPVTLNYLFGSQPGGPLKIGPITGLFNTPIGLTPLALSQIVIGASSSQGTITAFLANLPFSTPVVTIDEIPLLASITGHSEPVDIFPGGLTIPAMNPLSINLSGGTGAVTIPAITIGEIPFDLVAHSTLGPVHILIDLPAVPGFGNTTGAPSSGFFNSGAGGVSGFGNVGAMVSGGWNQAPSALLGGGSGVFNAGTLHSGVLNFGSGMSGLFNTSVLGLGAPALVSGLGSVGQQLSGLLASGTALHQGLVLNFGLADVGLGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIVSTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDTNTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYTSTIIPEFTVANIHASGGAGPIIVPSIQFPAIPLDLSATGHIGGFTIPPVSISPITVRIDPVFDLGPITVQDITIPALGLDPATGVTVGPIFSSGSIIDPFSLTLLGFINVNVPAIQTAPSEILPFTVLLSSLGVTHLTPEITIPGFHIPVDPIHVELPLSVTIGPFVSPEITIPQLPLGLALSGATPAFAFPLEITIDRIPVVLDVNALLGPINAGLVIPPVPGFGNTTAVPSSGFFNIGGGGGLSGFHNLGAGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGADISGVYNTGALGLITSALVSGFGNVGQQLAGLIYTGTGP
>NC_021251|3706703:3796139|3752640_3753381_-|WP_003911006.1|transposase|DBSCAN-SWA
MAIDPAAAYASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVTWAFHDRRGRKIDPQWANRRRLLTARERLSDKSFAKMRNRINAVDPRAQILSAWIAKEELRTLLSTVRTGGDPHLARHHLHRFLPGASTRRSPNCSPWPPPLTSHPRSTPSWSPASPTRASVVGEVAEMVGDIDGQCVQVEVPVPERGPAGCGGLDGLGRAGVSATPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR
>NC_021251|3706703:3796139|3767860_3768154_-|WP_003417749.1|DBSCAN-SWA
MTVRAVFRRTVGAQWPILLVGSIFAVGFVLAGANFWRRGALLIGIGVGVAAVLRLVLSEERAGLLVVRSKGIDFVTTVTVAAAMVYIASTIDPLGTG
>NC_021251|3706703:3796139|3785898_3786003_+|WP_003417895.1|DBSCAN-SWA
MWFALVNPEMLAAAATDLGGIRSGISAAYARPLR
>NC_021251|3706703:3796139|3735263_3736244_-|WP_031654342.1|DBSCAN-SWA
MLGGKGGDGGNGDHGGPATNPGSGSRGGAGGSGGNGGAGGNATGSGGKGGAGGNGGDGSFGATSGPASIGVTGAPGGNGGKGGAGGSNPNGSGGDGGKGGNGGAGGNGGSIGANSGIVGGSGGAGGAGGAGGNGSLSSGEGGKGGDGGHGGDGVGGNSSVTQGGSGFFGGKGGFGGDGGQGGPNGGGTVGTVAGGGGNGGVGGRGGDGVFAGAGGQGGLGGQGGNGGGSTGGNGGLGGAGGGGGNAPDGGFGGNGGKGGQGGIGGGTQSATGLGGDGGDGGDGGNGGNSGAKAGGAGGKGQAGQPNSGTEPGFGGDGGLGGAGATP
>NC_021251|3706703:3796139|3708258_3708420_+|WP_009937401.1|transposase|DBSCAN-SWA
MVVVGTDAHKYSHTFVATDEVGRQLGEKTVKATTAGHATAIMWAREQFGLELI
>NC_021251|3706703:3796139|3706703_3707965_-|WP_148286797.1|transposase|DBSCAN-SWA
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSLYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_021251|3706703:3796139|3766568_3766940_-|WP_003417739.1|DBSCAN-SWA
MSAATDLYAVHQALAGESRAIPTGSCPTVGVAGLTLGGGLGADSRHAGLTCDALKSATVVLPGGDAVSASADDHAELFWALRGGGGGNFGVTTSMTFARFPTADCDVVRVDFAPSAAAQVLVG
>NC_021251|3706703:3796139|3721124_3722354_-|WP_003417452.1|DBSCAN-SWA
MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN
>NC_021251|3706703:3796139|3713599_3715108_+|WP_003417416.1|DBSCAN-SWA
MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRRALLVGLTAASVGVLYGYDLSAIAGALLSLSEEFELTTREQELLTTTAVLGQIAGALGGGILANAIGRKKSVVLIVAGYAVFALLGATSVSVPMLVVARLLLGVTIGLSVVVVPVYVAESAPAAVRGSLVTAYQLATLSGIVVGYLVGYLLAGSHGWRAMFGLAAAPATLLLPLLWRMPDTARWYLLKGRIADARSALRRIQPEADIDAELADMAAAVDERGGGIGEMVRRPYLRATLFVIALGFLVQITGINAIIYYSPRLFAAMGFAGYFAMLALPAMVQVAGLAAVCASLFLVDRLGRRPILLSGIATMITADAVLITVFANDSDGGTGLVLGFAGVLLFIIGFNFGFGSLVWVYAAESFPSRLRSMGSSLMLTSTLTANAIVAAFSLTMLRVLGGAGVFAVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAERSPAADEP
>NC_021251|3706703:3796139|3766837_3767056_-|WP_157132559.1|DBSCAN-SWA
MRGGGHSYIGASSANGAMVLDLLGLPGGVHFDSATRNVRCRPRPISMRSIKRWPVRAGRFRPAAARPWVWRV
>NC_021251|3706703:3796139|3771362_3771914_-|WP_003417767.1|DBSCAN-SWA
MQQWVDCEFTGRDFRDEDLSRLHTERAMFSECDFSGVNLAESQHRGSAFRNCTFERTTLWHSTFAQCSMLGSVFVACRLRPLTLDDVDFTLAVLGGNDLRGLNLTGCRLRETSLVDTDLRKCVLRGADLSGARTTGARLDDADLRGATVDPVLWRTASLVGARVDVDQAVAFAAAHGLCLAGG
>NC_021251|3706703:3796139|3709903_3710842_-|WP_003417413.1|DBSCAN-SWA
MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRWDSQDTVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPEPVVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDPDPAHNEVVGRLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILGLVQRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
>NC_021251|3706703:3796139|3769690_3770881_+|WP_003900033.1|DBSCAN-SWA
MAPGSCEAPDVFNPAKLGPLTLRNRVIKAATFEARTPDALVTDDLIEYHRLPAAGGVAMTTVAYCAVSPGGRTGGNQIWMRPHAVPGLRRLTEAIHAEGAAISAQIGHAGPVADARSNQATALAPVRFFNPIAMRFAQKATREDIDDVLAAHAHAARLAVDAGFDAVEIHLGHNYLASAFLSPLLNRRDDEFGGSLQNRAKVARGLVMAVRRAVRQQVAVTAKLNMTDGIRGGITVDEALTTARWLQDDGGLDAIELTAGSSLVNPMYLFRGDAPVKEFAAAFKPPLRWGIRMTGHRFFREYPYRDAYLLREARLFRAELTIPLILLGGITNRTTMDLAMAEGFEFVAMARALLAEPDLVNRIAAEGSQVRSACTHCNQCMATIYRRTHCVVTGAP
>NC_021251|3706703:3796139|3789203_3790709_-|WP_003417905.1|DBSCAN-SWA
METFRTLLAKAALGNGISSTAYDTAWVAKLGQLDDELSDLALNWLCERQLPDGSWGAEFPFCYEDRLLSTLAAMISLTSNKHRRRRAAQVEKGLLALKNLTSGAFEGPQLDIKDATVGFELIAPTLMAEAARLGLAICHEESILGELVGVREQKLRKLGGSKINKHITAAFSVELAGQDGVGMLDVDNLQETNGSVKYSPSASAYFALHVKPGDKRALAYISSIIQAGDGGAPAFYQAEIFEIVWSLWNLSRTDIDLSDPEIVRTYLPYLDHVEQHWVRGRGVGWTGNSTLEDCDTTSVAYDVLSKFGRSPDIGAVLQFEDADWFRTYFHEVGPSISTNVHVLGALKQAGYDKCHPRVRKVLEFIRSSKEPGRFCWRDKWHRSAYYTTAHLICAASNYDDALCSDAIGWILNTQRPDGSWGFFDGQATAEETAYCIQALAHWQRHSGTSLSAQISRAGGWLSQHCEPPYAPLWIAKTLYCSATVVKAAILSALRLVDESNQ
>NC_021251|3706703:3796139|3783287_3784628_+|WP_003900036.1|DBSCAN-SWA
MAQLTALDAGFLKSRDPERHPGLAIGAVAVVNGAAPSYDQLKTVLTERIKSIPRCTQVLATEWIDYPGFDLTQHVRRVALPRPGDEAELFRAIALALERPLDPDRPLWECWIIEGLNGNRWAILIKIHHCMAGAMSAAHLLARLCDDADGSAFANNVDIKQIPPYGDARSWAETLWRMSVSIAGAVCTAAARAVSWPAVTSPAGPVTTRRRYQAVRVPRDAVDAVCHKFGVTANDVALAAITEGFRTVLLHRGQQPRADSLRTLEKTDGSSAMLPYLPVEYDDPVRRLRTVHNRSQQSGRRQPDSLSDYTPLMLCAKMIHALARLPQQGIVTLATSAPRPRHQLRLMGQKMDQVLPIPPTALQLSTGIAVLSYGDELVFGITADYDAASEMQQLVNGIELGVARLVALSDDSVLLFTKDRRKRSSRALPSAARRGRPSVPTARARH
>NC_021251|3706703:3796139|3767457_3767847_+|WP_003417745.1|DBSCAN-SWA
MNLRRHQTLTLRLLAASAGILSAAAFAAPAQANPVDDAFIAALNNAGVNYGDPVDAKALGQSVCPILAEPGGSFNTAVASVVARAQGMSQDMAQTFTSIAISMYCPSVMADVASGNLPALPDMPGLPGS
>NC_021251|3706703:3796139|3788511_3789165_+|WP_003417903.1|DBSCAN-SWA
MSISAVVFDRDGVLTSFDWTRAEEDVRRITGLPLEEIERRWGGWLNGLTIDDAFVETQPISEFLSSLARELELGSKARDELVRLDYMAFAQGYPDARPALEEARRRGLKVGVLTNNSLLVSARSLLQCAALHDLVDVVLSSQMIGAAKPDPRAYQAIAEALGVSTTSCLFFDDIADWVEGARCAGMRAYLVDRSGQTRDGVVRDLSSLGAILDGAGP

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148286797.1|3706703_3707965_-|transposase	IS3-like element IS987 family transposase	Q8W6R2	Burkholderia_virus	4.8e-82	58.7
WP_009937401.1|3708258_3708420_+|transposase	transposase	NA	NA	NA	NA
WP_003902445.1|3708441_3709971_+|transposase	IS110 family transposase	NA	NA	NA	NA
WP_003417413.1|3709903_3710842_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_003902446.1|3710850_3712218_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	9.0e-18	25.8
WP_003417415.1|3712286_3713504_+	D-alanyl-D-alanine carboxypeptidase DacB1	A0A1P8VVG5	Erythrobacter_phage	8.0e-10	27.3
WP_003417416.1|3713599_3715108_+	sugar porter family MFS transporter	NA	NA	NA	NA
WP_003417418.1|3715104_3716256_+	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_003417421.1|3716446_3717292_-	DUF732 domain-containing protein	NA	NA	NA	NA
WP_003900026.1|3717766_3718207_+	heavy metal-responsive transcriptional regulator	NA	NA	NA	NA
WP_003417435.1|3718240_3719110_-	inner membrane protein YhjD	NA	NA	NA	NA
WP_003417440.1|3719130_3720141_-|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_009940431.1|3720425_3721058_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_003417452.1|3721124_3722354_-	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_003900028.1|3722636_3723986_+	bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase	A0A0B5JD48	Pandoravirus	2.5e-12	26.5
WP_003417458.1|3723997_3725137_+	homoserine O-acetyltransferase	NA	NA	NA	NA
WP_003417461.1|3725133_3725865_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_038438875.1|3725873_3735215_-	PPE family protein	NA	NA	NA	NA
WP_031654342.1|3735263_3736244_-	hypothetical protein	NA	NA	NA	NA
WP_003417619.1|3741545_3741803_-	DUF3017 domain-containing protein	NA	NA	NA	NA
WP_003901612.1|3742058_3751532_-	PPE family protein	NA	NA	NA	NA
WP_049961743.1|3752157_3752604_+|transposase	transposase	NA	NA	NA	NA
WP_003911006.1|3752640_3753381_-|transposase	transposase	NA	NA	NA	NA
WP_009938650.1|3753675_3753963_-	hypothetical protein	NA	NA	NA	NA
WP_003417738.1|3765692_3766487_-	hypothetical protein	NA	NA	NA	NA
WP_003417739.1|3766568_3766940_-	FAD-binding oxidoreductase	A0A0B5JBT9	Pandoravirus	3.3e-15	56.4
WP_157132559.1|3766837_3767056_-	hypothetical protein	NA	NA	NA	NA
WP_003417741.1|3767082_3767343_-	hypothetical protein	NA	NA	NA	NA
WP_003417745.1|3767457_3767847_+	DUF732 domain-containing protein	NA	NA	NA	NA
WP_003417749.1|3767860_3768154_-	DUF3017 domain-containing protein	NA	NA	NA	NA
WP_003417751.1|3768150_3768996_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	NA	NA	NA	NA
WP_003417757.1|3769119_3769395_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_003417760.1|3769391_3769649_+	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_003900033.1|3769690_3770881_+	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_003417765.1|3770997_3771366_+	FHA domain-containing protein	NA	NA	NA	NA
WP_003417767.1|3771362_3771914_-	pentapeptide repeat protein MfpA	NA	NA	NA	NA
WP_003417769.1|3771920_3772502_-	ATP/GTP-binding protein	NA	NA	NA	NA
WP_003417772.1|3772482_3772851_-	DUF742 domain-containing protein	NA	NA	NA	NA
WP_003417776.1|3772828_3773221_-	hypothetical protein	NA	NA	NA	NA
WP_003901616.1|3773217_3775848_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_003901617.1|3776083_3776548_+|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_009938654.1|3776914_3778690_+	PE family protein	NA	NA	NA	NA
WP_003417881.1|3778690_3779335_-	nitroreductase family protein	NA	NA	NA	NA
WP_003417882.1|3779333_3779768_+	TIGR03667 family PPOX class F420-dependent oxidoreductase	NA	NA	NA	NA
WP_003908228.1|3779856_3783096_-	error-prone DNA polymerase DnaE2	A0A1C9LWS4	Streptomyces_phage	1.6e-118	32.4
WP_003900036.1|3783287_3784628_+	wax ester/triacylglycerol synthase family O-acyltransferase	NA	NA	NA	NA
WP_003417892.1|3784669_3785845_+	trehalose-phosphatase	NA	NA	NA	NA
WP_003417895.1|3785898_3786003_+	PE family protein	NA	NA	NA	NA
WP_003900037.1|3786081_3786723_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_003417897.1|3786723_3786972_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_014585402.1|3786976_3788404_+	amidase	NA	NA	NA	NA
WP_003417903.1|3788511_3789165_+	HAD family phosphatase	NA	NA	NA	NA
WP_003417905.1|3789203_3790709_-	type B diterpene cyclase	NA	NA	NA	NA
WP_016330438.1|3790713_3791604_-	diterpene synthase	NA	NA	NA	NA
WP_003918607.1|3791612_3793451_-	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_003417912.1|3793447_3794437_-	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_087902221.1|3794878_3796139_+|transposase	IS3-like element IS987 family transposase	Q8W6R2	Burkholderia_virus	9.6e-83	59.1