CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_021289	Burkholderia insecticola plasmid p1, complete sequence	1 crisprs	PD-DExK,csa3	1	0
NC_021294	Burkholderia insecticola chromosome 2, complete sequence	0 crisprs	csa3,cas3,DinG,DEDDh	0	1
NC_021295	Burkholderia insecticola plasmid p2, complete sequence	0 crisprs	csa3	0	0
NC_021288	Burkholderia insecticola chromosome 3, complete sequence	1 crisprs	NA	0	0
NC_021287	Burkholderia insecticola chromosome 1, complete sequence	1 crisprs	cas3,PD-DExK,DEDDh,DinG,csa3,WYL	8	2

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_021289_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021289_1

319666-319822

Orphan

Consensus_repeat	Method
GCCCCCCGTGCCTGTCCCCGAACCTCCGCCTCCCGTCCCGGCGTTCG	PILER-CR

2 spacers

The CRISPR arrays of NC_021289_1

>merge|NC_021289|1|319666-319822|PILER-CR
GTCCCCGAACCCCCGCCAGAACCGCCGCCCGTGCCCGTGCCCGACCCGCCGCCCGTGCCTGTCCCCGAACCTCCGCCTCCGGTCCCGGCGTTCGTTCCGCCGCCGCCGGTGCCCCCTGTGCCTGTCCCCGAACCTCCGCCTCCCGTTCCTGCGTTCG

>NC_021289|1|1|319666-319822|PILER-CR
GTCCCCGAACCCCCGCCAGAACCGCCGCCCGTGCCCGTGCCCGACCCG	CCGCCCGTGCCTGTCCCCGAACCTCCGCCT
CCGGTCCCGGCGTTCGTTCCGCCGCCGCCGGTGCCCCCTGTGCCTGTC	CCCGAACCTCCGCCT
CCCGTTCCTGCGTTCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_021289.1\|WP_016347944.1\|315792_316092_+\|DUF4148-domain-containing-protein	unknown	unknown	unknown
NC_021289.1\|WP_016347950.1\|321041_321545_+\|prepilin-peptidase	unknown	unknown	gnl\|CDD\|227295
NC_021289.1\|WP_016347945.1\|316164_317871_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NC_021289.1\|WP_016347940.1\|309376_311446_+\|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl\|CDD\|236645
NC_021289.1\|WP_016347952.1\|322048_322987_+\|Flp-pilus-assembly-protein-CpaB	unknown	unknown	gnl\|CDD\|274472
NC_021289.1\|WP_016347956.1\|327061_328015_+\|type-II-secretion-system-F-family-protein	unknown	unknown	gnl\|CDD\|227300
NC_021289.1\|WP_016347943.1\|315206_315650_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_021289.1\|WP_069915732.1\|328017_328971_+\|type-II-secretion-system-F-family-protein	unknown	unknown	gnl\|CDD\|224975
NC_021289.1\|WP_016347949.1\|320698_320875_+\|Flp-family-type-IVb-pilin	unknown	unknown	gnl\|CDD\|226366
NC_021289.1\|WP_016347938.1\|307134_307902_+\|DUF4410-domain-containing-protein	unknown	unknown	gnl\|CDD\|379584
NC_021289.1\|WP_016347937.1\|305990_306779_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NC_021289.1\|WP_016347939.1\|307965_309237_+\|cardiolipin-synthase	unknown	unknown	gnl\|CDD\|234967
NC_021289.1\|WP_016347936.1\|304544_305963_+\|UdgX-family-uracil-DNA-binding-protein	unknown	unknown	gnl\|CDD\|274850
NC_021289.1\|WP_162472051.1\|323110_324427_+\|pilus-assembly-protein-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|227299
NC_021289.1\|WP_016347941.1\|311520_313461_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NC_021289.1\|WP_144063545.1\|328981_329716_+\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|227343
NC_021289.1\|WP_016347951.1\|321541_322015_+\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|227296
NC_021289.1\|WP_144063575.1\|324429_325683_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|349765
NC_021289.1\|WP_016347955.1\|325686_327069_+\|CpaF-family-protein	unknown	unknown	gnl\|CDD\|227297
NC_021289.1\|WP_044043305.1\|313518_315060_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794

Protein	Function_ID	Function_description	E-value
NC_021289.1\|WP_016347950.1\|321041_321545_+\|prepilin-peptidase	gnl\|CDD\|227295	COG4960, CpaA, Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	4.04363e-13
NC_021289.1\|WP_016347945.1\|316164_317871_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	4.602e-69
NC_021289.1\|WP_016347940.1\|309376_311446_+\|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	1.46089e-107
NC_021289.1\|WP_016347952.1\|322048_322987_+\|Flp-pilus-assembly-protein-CpaB	gnl\|CDD\|274472	TIGR03177, pilus_cpaB, Flp pilus assembly protein CpaB. Members of this protein family are the CpaB protein of Flp-type pilus assembly. Similar proteins include the FlgA protein of bacterial flagellum biosynthesis.	1.26419e-42
NC_021289.1\|WP_016347956.1\|327061_328015_+\|type-II-secretion-system-F-family-protein	gnl\|CDD\|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	2.86651e-38
NC_021289.1\|WP_016347943.1\|315206_315650_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.63797e-17
NC_021289.1\|WP_069915732.1\|328017_328971_+\|type-II-secretion-system-F-family-protein	gnl\|CDD\|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	9.64921e-16
NC_021289.1\|WP_016347949.1\|320698_320875_+\|Flp-family-type-IVb-pilin	gnl\|CDD\|226366	COG3847, Flp, Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion].	1.42006e-09
NC_021289.1\|WP_016347938.1\|307134_307902_+\|DUF4410-domain-containing-protein	gnl\|CDD\|379584	pfam14366, DUF4410, Domain of unknown function (DUF4410). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 187 and 238 amino acids in length.	2.3374e-20
NC_021289.1\|WP_016347937.1\|305990_306779_-\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.27187e-67
NC_021289.1\|WP_016347939.1\|307965_309237_+\|cardiolipin-synthase	gnl\|CDD\|234967	PRK01642, cls, cardiolipin synthetase; Reviewed.	6.30858e-107
NC_021289.1\|WP_016347936.1\|304544_305963_+\|UdgX-family-uracil-DNA-binding-protein	gnl\|CDD\|274850	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain. This model represents a clade within the uracil-DNA glycosylase superfamily. Among characterized proteins, it most closely resembles the Thermus thermophilus uracil-DNA glycosylase TTUDGA, which acts uracil (deamidated cytosine) in both single-stranded DNA and U/G pairs of double-stranded DNA. This domain may occur either as a stand-alone protein or as the C-terminal domain of a fusion with another domain that always pairs with a particular radical-SAM family protein.	1.79156e-76
NC_021289.1\|WP_162472051.1\|323110_324427_+\|pilus-assembly-protein-N-terminal-domain-containing-protein	gnl\|CDD\|227299	COG4964, CpaC, Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion].	9.64448e-97
NC_021289.1\|WP_016347941.1\|311520_313461_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	1.10252e-20
NC_021289.1\|WP_144063545.1\|328981_329716_+\|pilus-assembly-protein	gnl\|CDD\|227343	COG5010, TadD, Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking and secretion].	2.40256e-15
NC_021289.1\|WP_016347951.1\|321541_322015_+\|pilus-assembly-protein	gnl\|CDD\|227296	COG4961, TadG, Flp pilus assembly protein TadG [Intracellular trafficking and secretion].	5.48331e-11
NC_021289.1\|WP_144063575.1\|324429_325683_+\|fimbrial-protein	gnl\|CDD\|349765	cd03111, CpaE-like, pilus assembly ATPase CpaE. This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains 7 genes: pilA, cpaA, cpaB, cpaC, cpaD, cpaE and cpaF. These genes are clustered together on chromosome.	4.69317e-57
NC_021289.1\|WP_016347955.1\|325686_327069_+\|CpaF-family-protein	gnl\|CDD\|227297	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion].	1.89113e-158
NC_021289.1\|WP_044043305.1\|313518_315060_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	9.17121e-111

>NC_021289.1|WP_016347945.1|316164_317871_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MKIREWTRAFMLAALAAPISSPHAFAQTTPRASVGGNPLDALPQVNAPPKPPVAVSVAPPAPTLDALLARHVTPAKIEIEGVKALPFDEVAARFTPFVGRDVTIGELIEAANGVTALYKQRGYALSFAFVPAQTFEDGVVRVTVVEGYIAQVVVKGQAGAAEKRIRAVAERLQADRPLTQANFERYINVLGMIPGVKTKANVAPPQNTDGATALELDVERKPFNFSTGIDFNHPGVQGILSATENGMLGLGESLTAAALLPKGRDDQTYYALNGTLPVGTDGFTTKVDASHYHGHPVDNPGLPSYIERTVVNDKLAFSAVYPFLLSNARSVVGTASVYASHDEDRLKNTIVAGNPYLSQRSQVRVAQLQLDYTGIGTGVVRRASFNVAKAFDVLGASKSAETNIAGYAPVNPVSLTFVRTGATHTQSNEWPFKIGTVVSATGQYSPDTLPTSEQISFGAQRFALGYQPGEASGDSGWGASFEVNRPLDVGMTYLKSFTPYVTIDAARVFLHGGTANPRRLSSVGIGFRVSDAKHYSIDLSVAKAIGDAPVESASRSPRINATLSYQLD
>NC_021289.1|WP_016347944.1|315792_316092_+|DUF4148-domain-containing-protein
MNKRTAPLAVIALSVAAWLAVPVAQAQDTAAAAAASTPKQIKKAQRKEARAKKNAELKQLEQNGYNPAGDQTNYPQNLQNAQAKINAQKAGKPAPASAP
>NC_021289.1|WP_016347943.1|315206_315650_+|MarR-family-transcriptional-regulator
METQLDKRFGFLVADVDRLCGNRFDELAKSSLNLTRAQCRVLAYLSHYGEVNQARLAGLLEVAPISAGRLLDRMEEGGWIERRLNPDDRRERQVRMTAKAEKALDRARRVGDEITSEALAGFSRQESEQLIGLLQRVRGNLSRIVDR
>NC_021289.1|WP_044043305.1|313518_315060_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MSTEAPTARAAAPLNRGMLTISIMLATLIQTLDSTIANVALPHMQGTLSASQDEITWVLTSYIVAAAIATPLTGWLSDQLSVKRLLCFSIAGFTVASAFCGLSETLGQIVASRLLQGVFGASLVPLSQSILLDINPREKQGQAMAVWGMGVMVGPILGPTLGGWLTDSYNWRWVFFINVPIGAFALFGVLTFLPAQAARRAVKFDAFGFATLGLAIGAFQAMLDRGEQLDWFGSMEIRIEALLAALAFVFFIAHTATAGARSFFKYQLLKDRNFATGTCFIFVIGAVMYATRALLPPMLQNLMNYPVATTGLVTAPSGAGTMVAMLFAGRLLKHVDARLMLLSGFLISALALWQMMHYTIVLSASDIVWPGVIQGFGLGLVFVPLSALTFSTLTPELRADGTATYSLMRNIGSSIGISIVQTLMTRNTQVAHADLAAQVTPFNPAMQSMLAGGSMQDMAMLNQTITQQASMIAYLNDFKLMFVATLLVVPLLLLIRPARQSAADEPVAHAAMD
>NC_021289.1|WP_016347941.1|311520_313461_+|tetratricopeptide-repeat-protein
MSLFERTLDAYLAGRTQEAESGCRDVLAANARHIDALHLLGLIRRDSGAFDEAESLIRQAIAEDEQARFAGSLGSVLLDQGRKTEAEASFRRAIELDARDPAAHYNLAILLLDVARADEAEAALRRVVALDTHFPGAHRNLGRAMFMLARHDDAQAFFRHAIEVDPADARAYTGRAAALTLADRLDDAKAACDEAIRIDPASCDAYVNLGAVLLRLERLEEAEAASRAALRLDAQRVHAHYNLGTTLLEADRLAEAEASLRQALEHDSSCVEAWLNLGRVLERLRRLDEAESAYRSGLKLRPSDPDLEGNLALVLLAQGQFAEGWPLYESRVPALRAEAHLWDAGLACPQWKGESLRGKSIVVVSEQGLGDTLQFCRYLPLLKAKGVKRLTVVCDAALARLVEGIEEVDACIRSSALLDAPKHDFWCLMMSLPLRFNTTLESIPAPMPYLRALNGLAENWKTRLPATTPKIGLVWAGEPRPDMKAAAPIDKRRSIHARQFMPLLQIPGATFVSLQLGATTRPQIGELPDALRPFDPMNDVTDFADTAAIIENLDLVIAVDTSTAHLAGALNKPVWMLSRFDQCWRWLIERDDTPWYPSMRLFRQTQPGDWDSVIARVADELKAFVAPAAKSKTAEAAKRPARKKRK
>NC_021289.1|WP_016347940.1|309376_311446_+|bifunctional-diguanylate-cyclase/phosphodiesterase
MHGTYNFWLVAASLVVATLASFTALDISGRIALLPQSRVRHAWLAGGAASMGIGIWSMHFIGVLAFELPIPLGYDLKITAGSLVIAVLVSFFALHVITSKRLTAKRLVASSVLMGAGIAAMHYTGDAAMRMRPAIQYDPSLFAASIVIAVVASGAALWIAHTLSAANLKNVMAKRVVSALVMGIAITGMHYTGNAAANFLPGSICGAANDVDARWLATTVALFTFAILIITLVLSRFDARTALLAGSVSRLNGQIVRMATFDTLTDLPNRRTMNERVERAIRHARHGGSRFAILFMDLDGFKTINDSLGHTVGDEVLKAFARRLQECVRGGDTVARLGGDEFIVMLENLNVPSDAEKMAERILDAMRRGLLAAGHPLQVMPSIGIALYPQDGDSVESMLKHADVAMYEAKRSGRSTYRFFEASMNEAAVRTLQIQQALHEALNSGHFYLLFQPKFRGASGELAGAEALIRLDHPQIGTLTPLEFIPIAERSGQIVQIGYWVVHETCRHLTQWRAQGRPPVKVAINLSPRQMYEADLVENIIKIVRDQGVPSEQIMFEITETVAMQDAPRTIEMIRAFQDNGFEIAIDDFGTGYSSLAYLQRFRAKQLKIDRFFTNGLDENGQEGRAIVSAIIALAHSLDMDVVAEGVETGSQLDRLQDMKCDEMQGFLLAMPLSADVFGGMLEKGAVSV
>NC_021289.1|WP_016347939.1|307965_309237_+|cardiolipin-synthase
MLTIALIVLTVVVTLVVVLVIANMSSGEKKIEHKIERLYASDDPQFIRSMGLLLGPPVGDGNRFEVLVNGDEIFPSMLDGIRSARETITFETFIYWSGAIGEEFAHALSDKARAGIPVHVLLDWVGSSKMDKRYLQMLRDSGAEVIQYHKPHWTGLGRMNDRTHRKLLVIDGRIGFTGGVGIAEEWTGHAQDEKHWRDTHFRVEGPVVGHMQAVFMDNWIKVTGNVLHGPRYFPEIAAAGDGLAHMFSSSPSGGSDDMQLMYLMAITAATHSIHLSSAYFVPDKLTINAIVEAAKRGVRVRIITPGKRIDTHTVREASRACWGDLLAAGVEIYEYQPTMFHCKLIVVDEYLVSVGSTNFDSRSFKLNDEANLNIYDRDFARRQTAIFDADVARSKRITLDEWRHRPLSEKMLERVVALLDSQL
>NC_021289.1|WP_016347938.1|307134_307902_+|DUF4410-domain-containing-protein
MSKSIKSFSFNAIVKKARGAALAAFVVGTAFLAGCASNPAQAASPYSQYAQSATPTLRADTIYVYAFASDASEVKLDDHGMISKIGSAISGDSQADKQTQDAAAAREEVANEIVAKLQSMGLRAVRADVAPPDDQSVLVVEGSFNTIDAGNRRRRMLIGLGAGESKVGATVQLVFKPAHGVPQVLEQFDAKADSGHAPGVAEMAGVGAAAGHVASSLAVSGGLHTVSETKHAGVSSDEKRLADSIAKQIAKLAQS
>NC_021289.1|WP_016347937.1|305990_306779_-|SDR-family-oxidoreductase
MDLKIANKLALVSGSTKGIGHAIAVALAREGARVILNGRSQSSVDEALGRLRELVPNAQAEGFAGDVSDAAQVNELVKRFPSVDILVNNMGIFDPKPFEEIPDEEWLRFFNANVMSGVRLSRAYLPKMKANNWGRVVFISSESGIQIPVEMIHYGMTKSAQISLARGLAETCTGTGVTVNSVLPGPTSSEGVTEFVEKLSGGKSFHDFEEQFFTEARPSSILKRFITPEEIASMVAYVCSELSSATNGAALRADGGVIRAAF
>NC_021289.1|WP_016347936.1|304544_305963_+|UdgX-family-uracil-DNA-binding-protein
MRTITIDDDFDAWRTAALDALAQQLTPESIDWRTTQAEPALFAAEAPALQQPSEAPQIRVSREFATLLKDAAHFRDERRWSFLYRVLWRWTQGDRSVASPADEDGARLYKMAKAVRRAQHDMIAYVRFRQRDAALGAPEYVAWYEPDHDVLVWGADHFAARMGRSTWLIATPHGAAMFDGEHLQIERRRALAAEHAVDTPDAAETLWMTYYRSIFNPARLNETALEQHMPVRFWKGLPEGALIPQLVSAARGGARRVAQAQGVGARGGKAVQVEAQEAQPERDAPTSLDTCRRCDLWRNATQAVHGAGPSDARIMLLGEQPGDQEDLKGEPFVGPAGQLLDDAMRRAGVPREQVYLTNAVKHFKWEPRGKRRLHKTPAQQEVDACAYWLEQELRDVGAQVIVTLGATALAALFGRRATLSAHLGRVVTYGDKSVVATYHPSYALRQNDEAARERTVAAIVEALERARTLIAR
>NC_021289.1|WP_016347949.1|320698_320875_+|Flp-family-type-IVb-pilin
MRATFKQFIRDRRGITAIEYGLIAGVLALGIMTAVGDVATQLKSTFQAITAELAKVGN
>NC_021289.1|WP_016347950.1|321041_321545_+|prepilin-peptidase
MIPIESAIFIGWALAVGLSDWRRRLIPNALVLAGGVGALTLAAARLSPFDISTGTALVGLAAGFVALLPFYLFGMMGAADVKVFAVLGAWCGPRALLGIWVAASLAAGVHALVLLARRRAVFALRDFPQEASLAERRRNSTPYGLLLAAAGIGHLALHALHALGARA
>NC_021289.1|WP_016347951.1|321541_322015_+|pilus-assembly-protein
MKHAHRTGQSGRRTQRGNMAIEFAIVFPLFFVVFYAIVTYSLIFVAQQSLTLAAEEGARAALRFQANATSIDDALARRADAACAAANGLTNWLAGLAHCSAAPAPCDYDGTLRCIAVTLDYGYAARPLVPTLPLFGLALPDSLVARAMVQLDPDNVL
>NC_021289.1|WP_016347952.1|322048_322987_+|Flp-pilus-assembly-protein-CpaB
MANLTRTLAILLFSVAAVLGIFAVMLARQPVPSPERDHAPPQSAVLAPSHRVPVVVAARDLPAGKTLDADALTVRMQAEPAPGTFGEPAAIVGRVPLAAVPKGAPLTADALSSGLADVVEPGERAVAVRIDETNAVGNFVRPGDFVDVFFTLKREGGAANGDAEISATQARLLLSKVRVLGVGDASVAQGVNKEAKDAALRQGSARTAVLAIRTGDIDALTLAESAGRLVLALRNSADAEVPPPHAFAPLVASARPDSDAARAAAGLSLGTLAGARTAARQADTPRAPRTPRMVTGDEIEVIRGGRAERIAY
>NC_021289.1|WP_162472051.1|323110_324427_+|pilus-assembly-protein-N-terminal-domain-containing-protein
MTMALAINTYAATRVETPMATDANVIALATGGQRSLAPGRTITRVALGDPSVADVNVLKGGGVLLVGKSAGTTNLMLWERGRNAPLSYTIEVASGASMALADVDAPKVRVLGKTAVLSGTAPTMDKHQRAVAAARASVGKDGALVDTSTVATKSVVQVDVKVVEFSKTVLKEAGFNLFSQNHAGFAFGTFAPSSLSSVTGGATNPLSVTATSPIGSAFNLLLNSTSRGLFANLSLLEGNNLARVLAQPTLVALSGQSASFLAGGEIPVPVPQSLGTTTIVYKPYGIGLSLTPTVLGPERIALKVAPEASQLDFAHAITIDGVSVPALTTRRAETAVELGDGESFVIGGLVDRETASNVNKVPLLGDLPIIGAFFKTLQYSQSDRELVIIVTPHLVAPIAKNAALPATPGQQSEQRDGPVWRSFVGGALSSDAAPGFSR
>NC_021289.1|WP_144063575.1|324429_325683_+|fimbrial-protein
MNTAAMPPPRFLCASPDAARRDWLQRALANAGAMETAPCDPAGLVARIGEVAPAIVFVDFGAGDASAAHASALAQTARDAFPSLPIVALGTLATPAPALAALRAGVRDFADMSGPPADVFAIAQRLLDERPPARSEAASRQGKVTVLLGARVGMGVSTLAANLAVSLHKRGAAAGRATALLDLGLPAADSALLLDTRSELHFVEAVRNLRRFDDTFVNTAFARHASGLALTTLPADLAEMRSISFASAMSMLNRLRAYFDQQIVDLGGFSNLDFVAQAVQAADETWLVCDPNVASAVSAIALLDALRTDDGTEAPKPGLVVNKFDAALNFGADQLAGRLNLPLIAVLPERAQALGRAVNQGRLLAECAERDPYVRALAPLVARLQGELREADAARDTKASRTALNVGHLLPNFLKRS
>NC_021289.1|WP_016347955.1|325686_327069_+|CpaF-family-protein
MAQDFSKDIAFANDLAEDAVAFAQSQQFQDVATAAHEHLLSRIEELGAEFGRWSRQAIHQFVDLEMDSFVRLRRIPLNESEVRLVAAALTKELAGFGPIEDLLADAAVEDILINGYSDVYVSRHGMLEKIPVRFADNAHLLRIVRRILAPIGRRLDESNPMVDARLPDGGRVNVVIEPLSIDGPVVSIRKFRRDPLRPDDLLANGTFNQDIASLLEAAVEARCNVLVSGGTSSGKTSLLNALAFFIPKHERVVTIEDTAELSLNHPHVVRLESRPGGFDGAGVVSIRDLLRNTLRMRPDRIIVGEVRGGEVLEMLQAMNTGHDGSMGTVHASSPRECLYRLEMLAGFAGFQGTEASLRRQIANAIDFIVQIGRLSNGRRRILSVTEVTGLSDNIIAMQELYRYDPAVDANGEETDRWNWLGIHPSSPKLAKYRQALGVAHAESFGQAGRFGGGFGGGFNV
>NC_021289.1|WP_016347956.1|327061_328015_+|type-II-secretion-system-F-family-protein
MYRAGALIAMLALLCAAAALMLWRRGTTGRERALAERFVERQVRGTQAAPSTHTPRPQQSVRPATTQTHLARARAAFANLMNRAGIARPRALACTTLAAAVIGALCAGMRAGPALGAGVAALVLAAVHAWLTWRAQKRYQRIVRQLPPFLDGIVRMIVIGHSVPAAFQAALTNAEAPLSECLDRALPMLRTGMEIDHALGTVARIYRVRELELVGSVLRVSVKYGGRSDVMLDRMAALMRDLEQADRELIALSTETRLSSWVLGLLPILLGAMVIVTNPAYFDAMWSDALGKRLVYVALALQLLGAWLLYRLARIRT
>NC_021289.1|WP_069915732.1|328017_328971_+|type-II-secretion-system-F-family-protein
MTPALLGALALAAAALAAGLFGMLAFGRYARMQRSARTLDHALKERTSAPAPASLDPAPSPRGLLAAIGRAGAAWLDTPFGRVAVANEDRRLLERCGYVDAQARGRFFAARVAGAVIAPLIVMTTGHGTAHGARFMMLLFMALSIGFMAPKWFVKRRAQARQRAVSNELPLFVDLLRLLQGVGLSLDQSLQVMVHDFRNVLPVLAKELALAQAQFATGRTREQSMKRLATSYDNEDLAAIVRLVIQVEQHGGAVQEPLKQFGDRLRETRRALLRERIGKLTVKMTGVMVITLLPALLIITAGPGFIAVVHALSGLHR
>NC_021289.1|WP_144063545.1|328981_329716_+|pilus-assembly-protein
MIRSTSLRALFATLICAALAACATKQENGYGVGIQAERQAALDQALQKESPPDTPGMYLALIDRMQAQGLWYASLAHIDAYEQQYGQSPDTILLRADALRQTGQSDASAVAYGRLANTPLAARGLRGLGLLAGEAADFSRAADLFASASRRAPTDALMLSDLGYARLRLGDVAGARVPLMKAAELAPNNPKILSNVALYLLASGEAANAQGLMTQQKFSADVQQAIRVDAKRVADAARASVASR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	319683-319712	0	1.0
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1249391-1249420	5	0.833
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP036456	Streptomonospora sp. M2 plasmid phiM2, complete sequence	6422-6451	6	0.8
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	109064-109093	6	0.8
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	MK977698	Microbacterium phage Busephilis, complete genome	8746-8775	6	0.8
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	MN096355	Mycobacterium phage Purky, complete genome	21928-21957	6	0.8
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NC_004683	Mycobacterium phage Che9c, complete genome	21811-21840	6	0.8
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	AY129333	Mycobacterium virus Che9c, complete genome	21811-21840	6	0.8
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	KM083128	Mycobacterium phage Sparky, complete genome	22689-22718	6	0.8
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP010957	Sphingobium sp. YBL2 plasmid 3pYBL2-3, complete sequence	23173-23202	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	38307-38336	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	MH155873	Microbacterium phage Paschalis, complete genome	8766-8795	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	MH590600	Microbacterium phage KaiHaiDragon, complete genome	8676-8705	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	MK875798	Microbacterium phage Piperis, complete genome	8773-8802	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	MT818415	Microbacterium phage Scumberland, complete genome	8991-9020	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NC_047993	Microbacterium phage Quhwah, complete genome	9121-9150	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	MN062719	Microbacterium phage PiperSansNom, complete genome	9070-9099	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	341564-341593	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP040824	Paraoceanicella profunda strain D4M1 plasmid pD4M1F, complete sequence	61787-61816	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	904009-904038	7	0.767
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP011383	Calothrix sp. 336/3 plasmid unnamed1	96156-96185	8	0.733
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	122127-122156	8	0.733
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NC_008271	Rhodococcus jostii RHA1 plasmid pRHL3, complete sequence	199217-199246	8	0.733
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	226076-226105	8	0.733
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP052758	Cellulosimicrobium sp. BI34T plasmid pCPRO01, complete sequence	44076-44105	8	0.733
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NZ_CP023524	Burkholderia gladioli pv. gladioli strain FDAARGOS_389 plasmid unnamed, complete sequence	87378-87407	8	0.733
NC_021289_1	1.1\|319714\|30\|NC_021289\|PILER-CR	319714-319743	30	NC_016655	Rhodococcus phage REQ1, complete genome	45331-45360	9	0.7

1. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
agaaccgccgcccgtgcccgtgcccgaccc	Protospacer
******************************

2. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.833

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
ggcatcgccgcccgtgcccgtgcccgtgcc	Protospacer
.* *.*********************  **

3. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP036456 (Streptomonospora sp. M2 plasmid phiM2, complete sequence) position: , mismatch: 6, identity: 0.8

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgtgccgcaccccgtgcccgtgcccgacca	Protospacer
 * .****  *******************

4. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.8

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
ctactcgccgcccgagcccgagcccgaccc	Protospacer
  * .********* ***** *********

5. spacer 1.1|319714|30|NC_021289|PILER-CR matches to MK977698 (Microbacterium phage Busephilis, complete genome) position: , mismatch: 6, identity: 0.8

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgacgacccgcccgtgcccgtgaccgaccc	Protospacer
 **    *************** *******

6. spacer 1.1|319714|30|NC_021289|PILER-CR matches to MN096355 (Mycobacterium phage Purky, complete genome) position: , mismatch: 6, identity: 0.8

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
accaacgccgcccgtggccgtacccgacca	Protospacer
*  * *********** ****.*******

7. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NC_004683 (Mycobacterium phage Che9c, complete genome) position: , mismatch: 6, identity: 0.8

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
accaacgccgcccgtggccgtacccgacca	Protospacer
*  * *********** ****.*******

8. spacer 1.1|319714|30|NC_021289|PILER-CR matches to AY129333 (Mycobacterium virus Che9c, complete genome) position: , mismatch: 6, identity: 0.8

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
accaacgccgcccgtggccgtacccgacca	Protospacer
*  * *********** ****.*******

9. spacer 1.1|319714|30|NC_021289|PILER-CR matches to KM083128 (Mycobacterium phage Sparky, complete genome) position: , mismatch: 6, identity: 0.8

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
accaacgccgcccgtggccgtacccgacca	Protospacer
*  * *********** ****.*******

10. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP010957 (Sphingobium sp. YBL2 plasmid 3pYBL2-3, complete sequence) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
gccttcgccgcccgtgcccgtgcccgtgcc	Protospacer
.   .*********************  **

11. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgccgcgccgcccgtgcccgtgcgcggcct	Protospacer
 *   ****************** **.**.

12. spacer 1.1|319714|30|NC_021289|PILER-CR matches to MH155873 (Microbacterium phage Paschalis, complete genome) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgacgacccgcccgtgcccgtggacgaccc	Protospacer
 **    ***************  ******

13. spacer 1.1|319714|30|NC_021289|PILER-CR matches to MH590600 (Microbacterium phage KaiHaiDragon, complete genome) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgacgacccgcccgtgcccgtgactgaccc	Protospacer
 **    *************** *.*****

14. spacer 1.1|319714|30|NC_021289|PILER-CR matches to MK875798 (Microbacterium phage Piperis, complete genome) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgacgacccgcccgtgcccgtggacgaccc	Protospacer
 **    ***************  ******

15. spacer 1.1|319714|30|NC_021289|PILER-CR matches to MT818415 (Microbacterium phage Scumberland, complete genome) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgacgacccgcccgtgcccgtggacgaccc	Protospacer
 **    ***************  ******

16. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NC_047993 (Microbacterium phage Quhwah, complete genome) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgacgacccgcccgtgcccgtggacgaccc	Protospacer
 **    ***************  ******

17. spacer 1.1|319714|30|NC_021289|PILER-CR matches to MN062719 (Microbacterium phage PiperSansNom, complete genome) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgacgacccgcccgtgcccgtggacgaccc	Protospacer
 **    ***************  ******

18. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgtcccgccgtccgtgccggtgcccgaggc	Protospacer
 *  ******.******* ********  *

19. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP040824 (Paraoceanicella profunda strain D4M1 plasmid pD4M1F, complete sequence) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
ggtaagcccgcccgagcccgtgccggaccc	Protospacer
.* *   ******* ********* *****

20. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
accttcgccgcccgagcccgtgcccgtgcc	Protospacer
*   .********* ***********  **

21. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP011383 (Calothrix sp. 336/3 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
ttagccgccgcccgtgcccgtgggcgatta	Protospacer
  *.******************  ***..

22. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cgtgccgccggccgtgcccgtgcccatctg	Protospacer
 * .****** **************. *.

23. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NC_008271 (Rhodococcus jostii RHA1 plasmid pRHL3, complete sequence) position: , mismatch: 8, identity: 0.733

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cggttcgccgcccgtgcacgggcccgacga	Protospacer
 *. .************ ** *******

24. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 8, identity: 0.733

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
gcgggcgctgcccgtgcccgtgcccgggcc	Protospacer
. .. ***.*****************. **

25. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP052758 (Cellulosimicrobium sp. BI34T plasmid pCPRO01, complete sequence) position: , mismatch: 8, identity: 0.733

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
atgaccgccgccggcgcccgtgcccgggtg	Protospacer
* .********* *.***********. .

26. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NZ_CP023524 (Burkholderia gladioli pv. gladioli strain FDAARGOS_389 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
gcgccggccgcccgtgcccgtgcctcaccg	Protospacer
. . * ******************. ***

27. spacer 1.1|319714|30|NC_021289|PILER-CR matches to NC_016655 (Rhodococcus phage REQ1, complete genome) position: , mismatch: 9, identity: 0.7

agaaccgccgcccgtgcccgtgcccgaccc	CRISPR spacer
cagcgagccgcccgtgatcgtgcccgacca	Protospacer
 ..   ********** .***********

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1395355 : 1445216

Tupanvirus(50.0%)

holin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044042808.1\|1395355_1396324_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_016355447.1\|1396642_1397896_+	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_016355448.1\|1398223_1401292_+	acetoacetate--CoA ligase	NA	NA	NA	NA
WP_044042611.1\|1401419_1402397_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_016355450.1\|1402393_1403566_-	porin	NA	NA	NA	NA
WP_016355452.1\|1403837_1404785_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_044042612.1\|1404827_1406363_-\|holin	choline-sulfatase	A0A2K9L727	Tupanvirus	1.7e-25	27.3
WP_016355454.1\|1406490_1407402_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_016355455.1\|1407521_1408397_+	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_016355456.1\|1408418_1409459_-	lipase chaperone	NA	NA	NA	NA
WP_016355457.1\|1409462_1410542_-	triacylglycerol lipase	NA	NA	NA	NA
WP_044042613.1\|1410873_1411728_-	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_144063487.1\|1411862_1413077_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_016355460.1\|1413101_1414400_-	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_016355461.1\|1414495_1415254_-	electron transfer flavoprotein beta-subunit	NA	NA	NA	NA
WP_016355462.1\|1415250_1416414_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_016355463.1\|1416418_1418335_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_016355464.1\|1418350_1420414_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_016355465.1\|1420455_1420986_-	4-vinyl reductase 4VR	NA	NA	NA	NA
WP_016355466.1\|1421015_1421987_-	membrane dipeptidase	NA	NA	NA	NA
WP_016355467.1\|1422006_1423281_-	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	3.9e-108	55.5
WP_016355469.1\|1423738_1424734_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_016355470.1\|1424737_1425268_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_044042614.1\|1425307_1426504_-	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	4.2e-11	26.6
WP_044042615.1\|1426746_1427334_+	transcriptional regulator BetI	NA	NA	NA	NA
WP_016355473.1\|1427360_1428830_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_016355474.1\|1428841_1430563_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	2.3e-50	28.9
WP_044042812.1\|1430629_1432057_-	MFS transporter	NA	NA	NA	NA
WP_044042616.1\|1432183_1432459_-	hypothetical protein	NA	NA	NA	NA
WP_016355477.1\|1432458_1432893_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_016355478.1\|1432889_1433543_-	sarcosine oxidase subunit gamma	NA	NA	NA	NA
WP_016355479.1\|1433532_1436535_-	sarcosine oxidase subunit alpha family protein	NA	NA	NA	NA
WP_016355480.1\|1436531_1436843_-	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_016355481.1\|1436864_1438109_-	sarcosine oxidase subunit beta family protein	NA	NA	NA	NA
WP_016355482.1\|1438146_1439541_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_016355483.1\|1439866_1440178_+	hypothetical protein	NA	NA	NA	NA
WP_044042617.1\|1440324_1441416_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_016355485.1\|1441465_1442233_+	class II aldolase/adducin family protein	NA	NA	NA	NA
WP_016355486.1\|1442261_1443218_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_016355487.1\|1443313_1444306_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_016355488.1\|1444313_1445216_-\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_021288

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CRISPR-Cas detection and classification

Crispr_ID: NC_021288_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021288_1

545713-545955

Orphan

Consensus_repeat	Method
GCGCTGGGCGGCGGCGCGGGCACGGCG	CRISPRCasFinder

3 spacers

The CRISPR arrays of NC_021288_1

>merge|NC_021288|1|545713-545955|CRISPRCasFinder
GCACTCGGCGGCGTGGCCGGAGCGGCACTCGGCGGCGCGGTCGGCGGAAGCACGGGCGCGGTGCTCGGCGGGGCGGTGGGCGGCGGCGCAGGCGGCGCGGTCACGTCGAACCGTCGCGAGCGCACGGGCGCGATCGTCGGCGGCGCGCTGGGCGGCGGCGCGGGCACGGCGGCAGGCAATGCAATGGGCGGCAGCGGCGGCGGCCTGATCGGCGCGGCGCTGGGCGGCGGCGCGGGCGCGGCG

>NC_021288|1|1|545713-545955|CRISPRCasFinder
GCACTCGGCGGCGTGGCCGGAGCGGCA	CTCGGCGGCGCGGTCGGCGGAAGCACGGGCGCGGTGCTCGGCGGG
GCGGTGGGCGGCGGCGCAGGCGGCGCG	GTCACGTCGAACCGTCGCGAGCGCACGGGCGCGATCGTCGGCGGC
GCGCTGGGCGGCGGCGCGGGCACGGCG	GCAGGCAATGCAATGGGCGGCAGCGGCGGCGGCCTGATCGGCGCG
GCGCTGGGCGGCGGCGCGGGCGCGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_021288.1\|WP_051180541.1\|546081_546627_-\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NC_021288.1\|WP_044042898.1\|543816_545169_-\|oxalate/formate-MFS-antiporter	unknown	unknown	gnl\|CDD\|275086
NC_021288.1\|WP_016347334.1\|547213_547909_-\|two-component-system-response-regulator-KdpE	unknown	unknown	gnl\|CDD\|182522
NC_021288.1\|WP_044042900.1\|550743_551319_-\|potassium-transporting-ATPase-subunit-KdpC	unknown	unknown	gnl\|CDD\|234724
NC_021288.1\|WP_016347319.1\|535733_535946_+\|hypothetical-protein	unknown	unknown	unknown
NC_021288.1\|WP_016347326.1\|540532_541786_-\|formyl-CoA-transferase	unknown	unknown	gnl\|CDD\|180055
NC_021288.1\|WP_016347338.1\|553506_555315_-\|potassium-transporting-ATPase-subunit-KdpA	unknown	unknown	gnl\|CDD\|235494
NC_021288.1\|WP_044042901.1\|555311_555407_-\|K(+)-transporting-ATPase-subunit-F	unknown	unknown	unknown
NC_021288.1\|WP_084675841.1\|533465_534638_-\|sorbosone-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|225044
NC_021288.1\|WP_044042902.1\|557433_558438_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NC_021288.1\|WP_016347327.1\|541814_543557_-\|oxalyl-CoA-decarboxylase	unknown	unknown	gnl\|CDD\|236433
NC_021288.1\|WP_016347335.1\|547905_550710_-\|sensor-histidine-kinase-KdpD	unknown	unknown	gnl\|CDD\|225115
NC_021288.1\|WP_016347325.1\|539979_540411_-\|PAS-sensor-domain-containing-protein	unknown	unknown	gnl\|CDD\|366402
NC_021288.1\|WP_044042896.1\|536038_536506_-\|ribonuclease	unknown	unknown	gnl\|CDD\|238340
NC_021288.1\|WP_016347340.1\|555844_557437_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_021288.1\|WP_044042897.1\|538105_539665_-\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|236507
NC_021288.1\|WP_016347318.1\|534780_535230_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226695
NC_021288.1\|WP_084675806.1\|546807_547257_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|133412
NC_021288.1\|WP_016347322.1\|536697_538095_-\|NAD(P)(+)-transhydrogenase-(Re/Si-specific)-subunit-beta	unknown	unknown	gnl\|CDD\|376743
NC_021288.1\|WP_044043109.1\|551362_553420_-\|potassium-transporting-ATPase-subunit-KdpB	unknown	unknown	gnl\|CDD\|234905

Protein	Function_ID	Function_description	E-value
NC_021288.1\|WP_051180541.1\|546081_546627_-\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	7.18516e-32
NC_021288.1\|WP_044042898.1\|543816_545169_-\|oxalate/formate-MFS-antiporter	gnl\|CDD\|275086	TIGR04259, oxalate:formate_antiport_protein, oxalate/formate antiporter. This model represents a subgroup of the more broadly defined model TIGR00890, which in turn belongs to the Major Facilitator transporter family. Seed members for this family include the known oxalate/formate antiporter of Oxalobacter formigenes, as well as transporter subunits co-clustered with the two genes of a system that decarboxylates oxalate into formate. In many of these cassettes, two subunits are found rather than one, suggesting the antiporter is sometimes homodimeric, sometimes heterodimeric.	0
NC_021288.1\|WP_016347334.1\|547213_547909_-\|two-component-system-response-regulator-KdpE	gnl\|CDD\|182522	PRK10529, PRK10529, DNA-binding transcriptional activator KdpE; Provisional.	2.07855e-107
NC_021288.1\|WP_044042900.1\|550743_551319_-\|potassium-transporting-ATPase-subunit-KdpC	gnl\|CDD\|234724	PRK00315, PRK00315, potassium-transporting ATPase subunit KdpC.	1.14764e-108
NC_021288.1\|WP_044042902.1\|557433_558438_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	5.47562e-86
NC_021288.1\|WP_016347326.1\|540532_541786_-\|formyl-CoA-transferase	gnl\|CDD\|180055	PRK05398, PRK05398, formyl-coenzyme A transferase; Provisional.	0
NC_021288.1\|WP_016347338.1\|553506_555315_-\|potassium-transporting-ATPase-subunit-KdpA	gnl\|CDD\|235494	PRK05482, PRK05482, potassium-transporting ATPase subunit A; Provisional.	0
NC_021288.1\|WP_084675841.1\|533465_534638_-\|sorbosone-dehydrogenase-family-protein	gnl\|CDD\|225044	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism].	3.95859e-99
NC_021288.1\|WP_016347327.1\|541814_543557_-\|oxalyl-CoA-decarboxylase	gnl\|CDD\|236433	PRK09259, PRK09259, putative oxalyl-CoA decarboxylase; Validated.	0
NC_021288.1\|WP_016347335.1\|547905_550710_-\|sensor-histidine-kinase-KdpD	gnl\|CDD\|225115	COG2205, KdpD, Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms].	0
NC_021288.1\|WP_016347325.1\|539979_540411_-\|PAS-sensor-domain-containing-protein	gnl\|CDD\|366402	pfam00989, PAS, PAS fold. The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.	1.75827e-17
NC_021288.1\|WP_044042896.1\|536038_536506_-\|ribonuclease	gnl\|CDD\|238340	cd00607, RNase_Sa, RNase_Sa. Ribonucleases first isolated from Streptomyces aureofaciens. In general, ribonucleases cleave phosphodiester bonds in RNA and are essential for both non-specific RNA degradation and for numerous forms of RNA processing. RNAse Sa is a guanylate specific endoribonuclease which belongs to the superfamily of microbial ribonucleases. Typical of this sub-family, the enzyme hydrolyses the phosphodiester bonds of RNA at the 3' oxygen end of guanosine residues to yield oligonucleotides with the guanosine-2',3'-cyclophosphate at the 3' end and the hydroxyl group at the 5' end. The terminal guanosine-2,3'-cyclophosphate is hydrolysed by guanyl RNAses to give guanosine-3'-phosphate.	2.63802e-49
NC_021288.1\|WP_016347340.1\|555844_557437_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NC_021288.1\|WP_044042897.1\|538105_539665_-\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	gnl\|CDD\|236507	PRK09424, pntA, Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha.	0
NC_021288.1\|WP_016347318.1\|534780_535230_-\|hypothetical-protein	gnl\|CDD\|226695	COG4244, COG4244, Predicted membrane protein [Function unknown].	2.76881e-10
NC_021288.1\|WP_084675806.1\|546807_547257_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|133412	cd04785, HTH_CadR-PbrR-like, Helix-Turn-Helix DNA binding domain of the CadR- and PbrR-like transcription regulators. Helix-turn-helix (HTH) CadR- and PbrR-like transcription regulators. CadR and PbrR regulate expression of the cadmium and lead resistance operons, respectively. These proteins are comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains have three conserved cysteines which comprise a putative metal binding site. Some members in this group have a histidine-rich C-terminal extension. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	1.55665e-52
NC_021288.1\|WP_016347322.1\|536697_538095_-\|NAD(P)(+)-transhydrogenase-(Re/Si-specific)-subunit-beta	gnl\|CDD\|376743	pfam02233, PNTB, NAD(P) transhydrogenase beta subunit. This family corresponds to the beta subunit of NADP transhydrogenase in prokaryotes, and either the protein N- or C terminal in eukaryotes. The domain is often found in conjunction with pfam01262. Pyridine nucleotide transhydrogenase catalyzes the reduction of NAD+ to NADPH. A complete loss of activity occurs upon mutation of Gly314 in E. coli.	0
NC_021288.1\|WP_044043109.1\|551362_553420_-\|potassium-transporting-ATPase-subunit-KdpB	gnl\|CDD\|234905	PRK01122, PRK01122, potassium-transporting ATPase subunit KdpB.	0

>NC_021288.1|WP_044042898.1|543816_545169_-|oxalate/formate-MFS-antiporter
MAIADTVGSGQSYGRRQNRWMQLAIGIVCMGLVANFQYAWTLFVMPMDAKHHWGQAAIQTAFTIFIVTETWLVPVEGWLVDKFGPRPVVMGGAICAAIGWVIDAHATTLMHLYIAAVVAGIGAGCVYGTCVGTALKWFPDKRGLAAGLTAAGFGAGAAVTVIPISNMIQRSGYEHAFMFFGIFQGVCIFLLALMLVRPNPPKGIVPAKRIVSTKIDYTTGQMVRAPIFWVLYLMFVCVAAGGVIATAQFGPIAKEYGFASMPVNILGVTLPLLAMTLSIDNLCNGFTRPLCGFISDKIGRENTMFIIFLGEGVALLGLMQFGQSPYMFMLFAALTFLCWGEIFSIFPATCADTFGSKYAAANAGTLYTAKGTASMLVPIASVLASLGSWNTVFIATAITSIAAGVCAKFVLAPMRRRWIENTIAETASPPGIGMAFQSDWTDAPSKSSAR
>NC_021288.1|WP_016347327.1|541814_543557_-|oxalyl-CoA-decarboxylase
MADVLEERAQAAAEEKAQQTTDGFHLVIDALKLNDIDTIFGLVGIPITDLARLAQAEGMRFIGFRHEQHAGNAAAIAGYMTQKPGICLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLNAAKPYAKAAYRVLHAEDIGIGVARAIRAAVSGRPGGVYLDLPAKLLAQTMDALKGQQSLIKVVDAAPRQLPSPDSVKRALDVIKGAKRPLILLGKGAAYAQADAQIRDLVEKSGIPYLPMSMAKGLLPDTHAQSASAARSFVLQEADCVVLIGARLNWLLAHGKGKTWGAAPKQFVQIDISPTEIDSNVAIAAPVIGDIGSCVSALVAGIDANFPKPSSEWTGAINERKNKNLEKMAATLAKNPSPMNFHSALRAIRDVLKTRPDINVVNEGANTLDYARSIIDMYEPRKRFDSGTWGIMGIGMGFAIGAAVTSGKQVVAIEGDSAFGFSGMELETICRYDLPVCTIVFNNNGVYRGTDVNPTGGKDVAPTVFVKNARYDKMIEAFGGIGFNATTPEELTHALEEAIKSGKPTLINAVIDEAAGTESGRLTNLNPQSAAMKK
>NC_021288.1|WP_016347326.1|540532_541786_-|formyl-CoA-transferase
MSDKPLKGIKIIDFTHVQAGPACTQMLAWFGADVIKVERPGSGDVTRNQLRDIPDADALYFTMLNSNKRSLTLDTKTDEGKEVLTKLIRESDVLVENFGPGALDRMGFSWENIHELNKKLIVASVKGFSDGHHYDDLKVYENVAQCAGGAASTTGFWDGPPTISAAALGDSNTGMHLAIGILTAIIGRQQTGKGQKVAVSMQDSVLNLCRVKLRDQQRLDRVGYLEEYPQYPHGTFSDVVPRGGNAGGGGQPGWVLKCKGWETDPNAYIYFTIQGHAWAPICRAIGKPEWIEDPNYMTAEARQPHIFDIFNTIEGWLADKTKFEAVDILRKFDIPCAPVLTMKELANDESLRASGSIVEVDHKVRGKYLTVGSPIKFSDLKPEITGSPLLGEHTEEVLLELGYSPEQVARMQEIRAV
>NC_021288.1|WP_016347325.1|539979_540411_-|PAS-sensor-domain-containing-protein
MTQTIDYEQLVNAIGDAVIISDASGAITLWNPAAERMFGFTQSEAMGQSLDLIIPERLRGRHWDGYHKTMATGETRYGHDLLKVPAVDKDGRSMSIAFTVALLHSPQGEVTSIVAIIRDETARFQEDRALRKRIAELEAKAAA
>NC_021288.1|WP_044042897.1|538105_539665_-|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha
MPMMIAVPRERYPGERRVALTPEVVGHLLKLGFEITVETGAGELAAFADEAYRAAGAHIAKDAPSLYAGADIVVKVRAPSIEPAADEVVWLREGSTLISFIWPAQNDALLTRLNARNITVLAMDCVPRISRAQKLDALSSMANMAGYRAVIEAAHQFGRGFMGQITAAGKIAPAKVMVIGAGVAGLAAIGAARSLGAIVRAFDTRPEVRQQVESMGAEFLELDYAEDGSGSGSGGYAKEMSPEFIAAEMALFAAQAKEVDVIVTTALIPGKPAPKLITADMVRSMRQGSVIVDMAAEQGGNCQLTQPGEAAFVEGVTIVGYTDLPSRMATQSSQLYGTNLRHLLTDLTPQKNGEIVIDIDDEVIGGVTVVLRGQVRWPLPKRPAAVAPTVEKPAATIAVTVEQKRRAGWIGIAGLVLAAVLLAALGAVAPPAFVAHFTVFVLAIFVGYQVVWNVTPALHTPLMSVTNAVSGIIVTGALLQVGTPDGLVAILSGLAILIATINIAGGFLVTQRMLNMFQR
>NC_021288.1|WP_016347322.1|536697_538095_-|NAD(P)(+)-transhydrogenase-(Re/Si-specific)-subunit-beta
MQNGIGSIAYLAASVLFILSLRGLSHPSTARRGNLYGVVGMVIAIVTTLWLNGGAALPVVAVLMAIGIAGGALLARRVEMTQMPQLVAALHSFVGLAAVLVAVASYLSPSSGAEDGGVAQSVHDVEIYLGVFIGAVTFTGSIAAFLKLQGIVGGKPLLLPMRHTLNLVGVFACLALGYVFLTAPDADVGISALLTMTAIAALIGVHLVMAIGGADMPVVVSMLNSYSGWAAAATGFMLSNDLLIVTGALVGSSGAILSYIMCRAMNRKFLSVILGGFGTVASSSTKAIEGEVAPVTVDEVGALLRDASEVVIVPGYGMAVAQAQATISEITKNLRNKGVKVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFSSTDVVLVIGANDIVNPGALEDPGSPIAGMPVLEVWKARTVIVSKRSMAAGYAGVDNPLFYKENTRMLFGDAKGSVDALLSHLAA
>NC_021288.1|WP_044042896.1|536038_536506_-|ribonuclease
MKRANAFSCILALSAILCGCGKGGSSNTTPESGASASSAPVQASAAASDTLAASGAQRGAPVSIAKAKLPGEAAETLRLIKAGGPFPFSEDGVLFRNSSALLPEHPRGYYHAYTVRTPGAADRGLRRIVCGGPRRQATDCYYTDDYYASFKRIAD
>NC_021288.1|WP_016347319.1|535733_535946_+|hypothetical-protein
MKRILVIADIPHDPFAQSEEATLTHAQMKRIVGGRSVLATVDGGPGMTTVNDFDINNAIWEGRIKGPMIN
>NC_021288.1|WP_016347318.1|534780_535230_-|hypothetical-protein
MSATTSSLRYRSRTATALFDLLDPIPYGLFVGTLIFDIIFAITANVFWAKGAAWLVTTGLILAIIPRFINLGHVWFGSRHVVTRAEKVDFWLNLLGIVAAVVNAFVHSRDGYAIVPSGVILSVITVVLLSVGHIALAFDKFGFQEARRD
>NC_021288.1|WP_084675841.1|533465_534638_-|sorbosone-dehydrogenase-family-protein
MQVPKFVGWKDNEAPKVADGLKIEKIASGLEHPRQVYALPNGDILVAESGSPNAEPVTTPKQLIAGMVQSRSGKESKGANRITLLRKRSDGSGEWEKHVFIDHLHSPFGMQLIGDTLYVADTDALLKFPYKTGETSVAEPGVELADLPDRINHHWTKALLASRDGKKLYVGVGSNSNVGENGLDVEYRRANVLEVDVASGASRIFAAGIRNPTGLQWEPKTGQLWTVANERDEIGADLVPDYLTSVKDGAFYGWPYSYYGQHVDTRVKEQRPDLVAKAIPPDFAIGSHVAPLGLMFYTGSNLPAQYKGGVFIGEHGSWDRSPLSGYAVAFVAFENGKPVGTPQPVVTGFVSADEKELHGAPVGLTQDKDGALVFADDAGNTVWRVTGAGG
>NC_021288.1|WP_051180541.1|546081_546627_-|cation-transporter
MFGVEVSSGFRGGSVSLLADSLDFLGDAANYGISLFVLGLSLSARARAARLKAVTMFAFGVGILGWAAWHFFIDRVPSVPTMGIVGTCALLANGAVAALLYRYRDGDSNMRSVWLCTRNDVLGNMAVLLAALGVFGTGSAWPDLAVATVMATLALTSAFQIFRQANAELREHPSGREVTSR
>NC_021288.1|WP_084675806.1|546807_547257_+|helix-turn-helix-domain-containing-protein
MTAMYSIGMLSRFSGVNIETIRYYEKIDLLRAPGRASNGYRQYDSASLQRLAFIRRGRELGFSIDEMRELLSLADHPERPCADADGMTRAHLDDIDGKIRDLQRMRRALRQVADCRGRTAEHCELLQALAMPDASSTSRPSADTPRPFR
>NC_021288.1|WP_016347334.1|547213_547909_-|two-component-system-response-regulator-KdpE
MIDMRHTVLIVEDDPQIRRFVRSTLQSNDVEVVEADTGRAGLREIATRQPDLVVLDLGLPDTDGIDVIRELRGWTQVPVIVLSARSSEAMKVSALDAGADDYLTKPFGVSELLARVRAQLRRTTRALEEAPAVSFGEIVVDLARREVTRAGQPVRLTPTEYRLLSVLMRHAGRVLTHRQLLRDVWGPAQVDNAHYLRVYMGHLRQKLEKDPAQPEHIITETAVGYRLMGVR
>NC_021288.1|WP_016347335.1|547905_550710_-|sensor-histidine-kinase-KdpD
MTRPNPDELLDKLQREEEKLQRGRLKVFFGASAGVGKTFAMLQAARRRQEEGVDVVVGVVETHGRKETLALLDGLDTLPAARIDYRGRLLAEFDLDAALARKPQLVLVDELAHSNVQGSRHLKRWQDVQELLDAGIDVYTTVNVQHLESLNDIVGRITGIRVWETVPDRVFDLADEVTLVDLPPEELLDRLRDGKVYLPTQAENAVRNFFRKGNLIALRELALRRTADRVDAQMREYRADQSIERIWRARERLIACVGPGPESAALVRAAARLAAALKADWLAVYVETPKLQRLSDDQRRRTLDALKLASELGAETVTLDGADAAATLIDYARMRNVSKLVASASAAQGWQRYFDRPVSERIIRQAADIDVTLVSTGTRDTQPHSTLTFGALRDGMHSPPRAYAYALAIGAGITLVASALAAQRFAVTNLVMLYLLGVIFAAVRLGRGPGVMLSFLSVAAFDYFFVAPVMSFSVGDTQYLLTFAVMLLTSLTISHLTSSLRREARIASQRERRTGAMYAMTKELAAALMTEQIIEIGTRHIAEVFQAKAAILLPDSGEKVQQKVAEASPETTLGRTELDLDIAQWVYDQQKPAGRSTDTLPAAQALYLPLKAPMRTRGVLAFAAQRTADLAVPEQRRMIETFAAQIALALERVHYVEIAQDALVNMESERMRNSLLSAISHDLRTPLTSIVGFASLLDEQVKAGEERTARSQELVHAIHDEALRMSGLVTNLLDMARLQAGAIRLNRQWSMLEETVGAALNGLRRTLMGRRVQTRIPADLPLLQLDAVLMDRLFANLLENAAKYTPEGTDIDISARLEQEDGKRFVRVRVDDRGPGIQAGMQKRLFEKFTRGEKESAQSGVGLGLAICRAIVEAHGGEIGAENRLENGSVAGASFWFTLPAEGTPPAVEMSPDEEAALDEASARRSDKAGESKS
>NC_021288.1|WP_044042900.1|550743_551319_-|potassium-transporting-ATPase-subunit-KdpC
MKNVLRPALVLFVALTVVTGLIYPAVVTAIGQAAFHHQANGSLTERNGKVIGSDIIGQQFDAPQYFWGRLSATTPNPYNAGSSSGSNLGPTNPALADEVKGRIDALHAADPANQMAIPVDLVTSSGSGLDPEISPAAAAYQVARVAKARGMTVEQVQALVGQATMGRQFGVLGEPRVNVLRLNLALDAAKG
>NC_021288.1|WP_044043109.1|551362_553420_-|potassium-transporting-ATPase-subunit-KdpB
MFDPTLLKPAIVDSFRKLAPRTQLRNPVMFCVYVGSILTTVLWIAALAGQAEAPAGFILAIALWLWFTVLFANFAEALAEGRSKAQAASLRQAKHNVMAKKLNEPHPKSPIRITTSTDLVKGDVVLVETGDVIPADGEVIEGVASVDESAITGESAPVIRESGGDFSSVTGGTRVLSDWIVVRVSVNPGEAFLDRMIAMVEGAKRQKTPNEIALTILLVALTLVLLFATATLLPFSMFSVEAAKQGHVVTITALVALLVCLIPTTIGGLLSAIGVAGMSRMMQANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASAFTAAPGVQERDLADAAQLASLADETPEGRSIVVLAKQRFNIRERDMASLHATFLAFSAQTRMSGVDLPGREIRKGSADALKRYIEERGGRFPQEVQTAVDDVARRGSTPLVVAETSHGTTRALGVIELKDIVKGGIKERFAELRKMGIKTVMVTGDNRLTAAAIAAEAGVDDFLAEATPEAKLATIRSHQSEGRLVAMTGDGTNDAPALAQADVAVAMNTGTQAAKEAGNMVDLDSNPTKLIEIVEIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFATTYPQLRVLDVMHLASPSSAILSAVIFNALIIVFLIPLALKGVKYRALGAASLLRRNLLIYGLGGLLLPFPFIKLIDMVITALGWS
>NC_021288.1|WP_016347338.1|553506_555315_-|potassium-transporting-ATPase-subunit-KdpA
MNANTLMQTALFIVVLIALAIPLGRYIASVLDGSSVVVRRIGRPLENLLYRLAGVDPEAEMSWKHYALAVMLFNVLGALVLYAILRLQGMLPANPQGMAGMTPDAAFNTAISFVTNTNWQDYGGESTLGYLAQMLGLTVQNFVSAATGIAVVIALIRGFKRHTAQTIGNFWVDLTRTTLYILAPLAVIFALVFVSQGAIQNFKAYEDVSTLQVTTYQAPKTDAQGNAVKDAKGNPVMQDVKADKQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPFENPTPFSNFMQTLAMLIIPAALCVVFGRTVGDKRQGYAVLAAMTIAFAVACWGEIASEQAGNPLYASLKVDASASALQAGGNMEGKETRFGIAQSGIFTVATTAASCGAVANTHDSLTPLGGLVPMLLIQLGEVIFGGVGSGLYGILAFALLAVFVAGLMIGRTPEYVGKKIESFEMKMVSIVILLTPLLVLAGTSIAVLTASGTAGIANPGAHGFSEVLYAFSSAANNNGSAFGGLSVNTPFYNVMLAIAMWFGRFGSLIPILAIAGSLAAKKRLAVTAGTLPTHGPLFVVLLLGTLVLVGALTYIPALALGPIVEHITMVTGH
>NC_021288.1|WP_044042901.1|555311_555407_-|K(+)-transporting-ATPase-subunit-F
MSAWMVWLAAASTLLLFVYLVYALLRAEDLE
>NC_021288.1|WP_016347340.1|555844_557437_+|sugar-ABC-transporter-ATP-binding-protein
MSEPVAGAAASSARAPLIRVAGVTKRFGGVQALRGVNFEVLPGEVHALLGENGAGKSTLIKILSGVHTYDEGSIEIVGQKVAFESPAKSREAGVAVVYQDLSLVESLSVGANLMLGREPRTRLGFVKQRELMAQVSAFLREHNIPLDPRVPVDSLPFAYRQMTEICKALMGDVRVLILDEPTSALTGGEEQILFDAIRTVTARGVGVIYVTHRLNEVFRISQRVTILRDGANAGHFATAETDMKQLVAAIVGPRHAAMQAKQETTTGTSAAHAQRDIAQIKGTPALTLSNVSNARLRNVNFAVHKGEVHGLAGLIGSGRTEILQTIFGLLPLESGSIDLDGQPFAARRPADAIERGIALVPEDRHVQGLVLDHSIERNLTLPRLPQFSRGGWLRAKAAALQAQIAMKQLSVKAPDASTQVKFLSGGNQQKVVFAKWNHPRPKVLLLDEPTVGVDVGAREEIYGVVHDAARAGTGVVVVSSDLDELLRLCDRISIVVDGSIQRTVARGEIRHAEELHHLIQTLRTTEEPAT
>NC_021288.1|WP_044042902.1|557433_558438_+|ABC-transporter-permease
MNESVSPTPLPAEQQSAQRRSRAWRIARTLLQGDRPYMLYIAFAILLVVFSFASPWFLSIDNFLNIGRQTALVSIIAIGMTFVIIARQIDLSVGSSLALSGMAAALAMSHINDSWIVGAIAGIGTGAIVGAINGFVTTRLSIPSFLVTLGSLSAARGLALMVTTTRPEIITNDTFISIFGEGSIAGVPAPILWTLLAVVGGILLLHYSVFGRQIYAAGGNPTAALYSGINIRRVTTLAFVLTGVLAGLAALVLSARSHAARPDVVQGMELDVIASVTLGGCSLFGGRGFILGTLLGSLIIGTLNNGLVLLGVSSSLQLVIKGVIIVAAVAFTRK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NC_021287

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CRISPR-Cas detection and classification

Crispr_ID: NC_021287_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021287_1

507941-508823

Orphan

Consensus_repeat	Method
GTTTCCTCCGCGTGCGCGGAGATAGACCC	CRISPRCasFinder
GNTTNCTCCGCGTGCGCGGAGATNGACC	CRT
TTCCTCCGCGTGCGCGGAGATAGACC	PILER-CR

14 spacers

The CRISPR arrays of NC_021287_1

>merge|NC_021287|1|507941-508823|CRISPRCasFinder,CRT,PILER-CR
GTTTCCTCCGCGTGCGCGGAGATAGACCCCAATGATTGCACCGCCTGATGCGGGTCAGGATGTTTCCTCCGCGTGCGCGGAGATAGACCCGGGGCTTGGCTCCAAGGTTGCCAGTTCGTGCCGTTTCCTCCGCGTGCGCGGAGATAGACCCTCGACCGGAATTTCTATTTGATCGACGCAGTGGTTTCCTCCGCGTGCGCGGAGATAGACCCGCGTCGTCCGACTCCTTCAGTGCGGGCGTCGGGGTTGCTCCGCGTGCGCGGAGATAGACCCAAGAAGGCCGCCGCCCATGACGGCGTACAGGTGGTTGCTCCGCGTGCGCGGAGATAGACCTGATGGCGATTTGATGAGGGTGCGAGCGCGTTGGGTTGCTCTGCGTGCGCGGAGATGGACCTTCAGAATAGTCGTGTATGCGCTGCGCGACTCGGGTTGCTCCGCGTGCGCGGAGATAGGCCCTCGATCACGGCAGGTTGCATGATTTTCTTACCGGTTGCTCCGCGTGCGCGGAGATGGACCCGAGGTCACGAAAGGAGAGTTCGCCACTCCTACGTTTCCTCCGCGTGCGCGGAGATGGACCCCTGCGCGACTTCCAGTTCATGCCGCTGAACGTGTTTCCTCCGCGTGCGCGGAGATGGACCGGCCGTGCGCTTGAATATCAGCCTGCCCGAGCAGTTTCCTCCGCGTACGCGGTGATGGGCCTCGCTCGGAGACGCGGGAATCTTGTCGCCTGCCGGTTGCTCCGCGTGTGCGGAGATGGACCTCAGTTGAGCTTGTAGCCGCGCATGTAGACGCGGTTTTCTTTGCGTGTGCGGAGATGGGCCCGGTCAACACGCTTCGATGATGGGTTTCAATGAGTTTCCTCCGCCTGCACGCAGATAGACCC

>NC_021287|1|1|507941-508823|CRISPRCasFinder
GTTTCCTCCGCGTGCGCGGAGATAGACCC	CAATGATTGCACCGCCTGATGCGGGTCAGGAT
GTTTCCTCCGCGTGCGCGGAGATAGACCC	GGGGCTTGGCTCCAAGGTTGCCAGTTCGTGCC
GTTTCCTCCGCGTGCGCGGAGATAGACCC	TCGACCGGAATTTCTATTTGATCGACGCAGTG
GTTTCCTCCGCGTGCGCGGAGATAGACCC	GCGTCGTCCGACTCCTTCAGTGCGGGCGTCGG
GGTTGCTCCGCGTGCGCGGAGATAGACCC	AAGAAGGCCGCCGCCCATGACGGCGTACAGGT
GGTTGCTCCGCGTGCGCGGAGATAGACCT	GATGGCGATTTGATGAGGGTGCGAGCGCGTTG
GGTTGCTCTGCGTGCGCGGAGATGGACCT	TCAGAATAGTCGTGTATGCGCTGCGCGACTCG
GGTTGCTCCGCGTGCGCGGAGATAGGCCC	TCGATCACGGCAGGTTGCATGATTTTCTTACC
GGTTGCTCCGCGTGCGCGGAGATGGACCC	GAGGTCACGAAAGGAGAGTTCGCCACTCCTAC
GTTTCCTCCGCGTGCGCGGAGATGGACCC	CTGCGCGACTTCCAGTTCATGCCGCTGAACGT
GTTTCCTCCGCGTGCGCGGAGATGGACCG	GCCGTGCGCTTGAATATCAGCCTGCCCGAGCA
GTTTCCTCCGCGTACGCGGTGATGGGCCT	CGCTCGGAGACGCGGGAATCTTGTCGCCTGCC
GGTTGCTCCGCGTGTGCGGAGATGGACCT	CAGTTGAGCTTGTAGCCGCGCATGTAGACGCG
GTTTTCTTTGCGTGTGCGGAGATGGGCCC	GGTCAACACGCTTCGATGATGGGTTTCAATGA
GTTTCCTCCGCCTGCACGCAGATAGACCC

>NC_021287|1|1|507941-508761|CRT
GTTTCCTCCGCGTGCGCGGAGATAGACC	CCAATGATTGCACCGCCTGATGCGGGTCAGGAT
GTTTCCTCCGCGTGCGCGGAGATAGACC	CGGGGCTTGGCTCCAAGGTTGCCAGTTCGTGCC
GTTTCCTCCGCGTGCGCGGAGATAGACC	CTCGACCGGAATTTCTATTTGATCGACGCAGTG
GTTTCCTCCGCGTGCGCGGAGATAGACC	CGCGTCGTCCGACTCCTTCAGTGCGGGCGTCGG
GGTTGCTCCGCGTGCGCGGAGATAGACC	CAAGAAGGCCGCCGCCCATGACGGCGTACAGGT
GGTTGCTCCGCGTGCGCGGAGATAGACC	TGATGGCGATTTGATGAGGGTGCGAGCGCGTTG
GGTTGCTCTGCGTGCGCGGAGATGGACC	TTCAGAATAGTCGTGTATGCGCTGCGCGACTCG
GGTTGCTCCGCGTGCGCGGAGATAGGCC	CTCGATCACGGCAGGTTGCATGATTTTCTTACC
GGTTGCTCCGCGTGCGCGGAGATGGACC	CGAGGTCACGAAAGGAGAGTTCGCCACTCCTAC
GTTTCCTCCGCGTGCGCGGAGATGGACC	CCTGCGCGACTTCCAGTTCATGCCGCTGAACGT
GTTTCCTCCGCGTGCGCGGAGATGGACC	GGCCGTGCGCTTGAATATCAGCCTGCCCGAGCA
GTTTCCTCCGCGTACGCGGTGATGGGCC	TCGCTCGGAGACGCGGGAATCTTGTCGCCTGCC
GGTTGCTCCGCGTGTGCGGAGATGGACC	TCAGTTGAGCTTGTAGCCGCGCATGTAGACGCG
GTTTTCTTTGCGTGTGCGGAGATGGGCC

>NC_021287|1|1|507943-508517|PILER-CR
TTCCTCCGCGTGCGCGGAGATAGACC	CCAATGATTGCACCGCCTGATGCGGGTCAGGATGT
TTCCTCCGCGTGCGCGGAGATAGACC	CGGGGCTTGGCTCCAAGGTTGCCAGTTCGTGCCGT
TTCCTCCGCGTGCGCGGAGATAGACC	CTCGACCGGAATTTCTATTTGATCGACGCAGTGGT
TTCCTCCGCGTGCGCGGAGATAGACC	CGCGTCGTCCGACTCCTTCAGTGCGGGCGTCGGGG
TTGCTCCGCGTGCGCGGAGATAGACC	CAAGAAGGCCGCCGCCCATGACGGCGTACAGGTGG
TTGCTCCGCGTGCGCGGAGATAGACC	TGATGGCGATTTGATGAGGGTGCGAGCGCGTTGGG
TTGCTCTGCGTGCGCGGAGATGGACC	TTCAGAATAGTCGTGTATGCGCTGCGCGACTCGGG
TTGCTCCGCGTGCGCGGAGATAGGCC	CTCGATCACGGCAGGTTGCATGATTTTCTTACCGG
TTGCTCCGCGTGCGCGGAGATGGACC	CGAGGTCACGAAAGGAGAGTTCGCCACTCCTACGT
TTCCTCCGCGTGCGCGGAGATGGACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_021287.1\|WP_016344405.1\|498838_499162_+\|AzlD-domain-containing-protein	unknown	unknown	gnl\|CDD\|377512
NC_021287.1\|WP_016344422.1\|519401_519779_+\|DUF427-domain-containing-protein	unknown	unknown	gnl\|CDD\|377265
NC_021287.1\|WP_016344418.1\|512777_514079_+\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|182388
NC_021287.1\|WP_016344410.1\|504057_504948_+\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl\|CDD\|237571
NC_021287.1\|WP_016344417.1\|512115_512778_+\|response-regulator	unknown	unknown	gnl\|CDD\|182612
NC_021287.1\|WP_016344420.1\|517089_518598_+\|DegQ-family-serine-endoprotease	unknown	unknown	gnl\|CDD\|273938
NC_021287.1\|WP_044041150.1\|496805_497726_-\|branched-chain-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|235841
NC_021287.1\|WP_016344421.1\|518753_519239_+\|hypothetical-protein	unknown	unknown	unknown
NC_021287.1\|WP_016344414.1\|508900_510007_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238883
NC_021287.1\|WP_016344419.1\|515945_516752_+\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|236764
NC_021287.1\|WP_173405448.1\|520743_521403_+\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238496
NC_021287.1\|WP_044041152.1\|505611_506799_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NC_021287.1\|WP_044041151.1\|502866_503931_+\|fructose-bisphosphate-aldolase-class-II	unknown	unknown	gnl\|CDD\|181691
NC_021287.1\|WP_044041893.1\|501127_502564_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NC_021287.1\|WP_051180370.1\|498062_498842_+\|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224215
NC_021287.1\|WP_016344416.1\|510278_511886_-\|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase	unknown	unknown	gnl\|CDD\|224938
NC_021287.1\|WP_016344407.1\|499590_500787_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NC_021287.1\|WP_016344413.1\|506833_507865_+\|threonylcarbamoyl-AMP-synthase	unknown	unknown	gnl\|CDD\|223088
NC_021287.1\|WP_016344411.1\|505001_505523_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|376377
NC_021287.1\|WP_016344423.1\|519854_520652_+\|carbon-monoxide-dehydrogenase-subunit-G	unknown	unknown	gnl\|CDD\|176853

Protein	Function_ID	Function_description	E-value
NC_021287.1\|WP_016344405.1\|498838_499162_+\|AzlD-domain-containing-protein	gnl\|CDD\|377512	pfam05437, AzlD, Branched-chain amino acid transport protein (AzlD). This family consists of a number of bacterial and archaeal branched-chain amino acid transport proteins. AzlD is known to be involved in conferring resistance to 4-azaleucine although its exact role is uncertain.	6.24891e-18
NC_021287.1\|WP_016344422.1\|519401_519779_+\|DUF427-domain-containing-protein	gnl\|CDD\|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	2.38698e-40
NC_021287.1\|WP_016344418.1\|512777_514079_+\|two-component-sensor-histidine-kinase	gnl\|CDD\|182388	PRK10337, PRK10337, sensor protein QseC; Provisional.	2.80037e-72
NC_021287.1\|WP_016344410.1\|504057_504948_+\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl\|CDD\|237571	PRK13961, PRK13961, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	0
NC_021287.1\|WP_016344417.1\|512115_512778_+\|response-regulator	gnl\|CDD\|182612	PRK10643, PRK10643, two-component system response regulator PmrA.	2.24165e-83
NC_021287.1\|WP_016344420.1\|517089_518598_+\|DegQ-family-serine-endoprotease	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	4.02018e-177
NC_021287.1\|WP_044041150.1\|496805_497726_-\|branched-chain-amino-acid-transaminase	gnl\|CDD\|235841	PRK06606, PRK06606, branched-chain amino acid transaminase.	0
NC_021287.1\|WP_016344414.1\|508900_510007_-\|hypothetical-protein	gnl\|CDD\|238883	cd01847, Triacylglycerol_lipase_like, Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Members of this subfamily might hydrolyze triacylglycerol into diacylglycerol and fatty acid anions.	4.57405e-56
NC_021287.1\|WP_016344419.1\|515945_516752_+\|OmpA-family-protein	gnl\|CDD\|236764	PRK10808, PRK10808, outer membrane protein A; Reviewed.	1.37023e-28
NC_021287.1\|WP_173405448.1\|520743_521403_+\|cysteine-hydrolase	gnl\|CDD\|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	1.27914e-54
NC_021287.1\|WP_044041152.1\|505611_506799_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	0
NC_021287.1\|WP_044041151.1\|502866_503931_+\|fructose-bisphosphate-aldolase-class-II	gnl\|CDD\|181691	PRK09196, PRK09196, fructose-bisphosphate aldolase class II.	0
NC_021287.1\|WP_044041893.1\|501127_502564_+\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NC_021287.1\|WP_051180370.1\|498062_498842_+\|AzlC-family-ABC-transporter-permease	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	3.20285e-44
NC_021287.1\|WP_016344416.1\|510278_511886_-\|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase	gnl\|CDD\|224938	COG2027, DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane].	1.13948e-106
NC_021287.1\|WP_016344407.1\|499590_500787_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NC_021287.1\|WP_016344413.1\|506833_507865_+\|threonylcarbamoyl-AMP-synthase	gnl\|CDD\|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	2.16053e-67
NC_021287.1\|WP_016344411.1\|505001_505523_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|376377	pfam00731, AIRC, AIR carboxylase. Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.	6.71942e-80
NC_021287.1\|WP_016344423.1\|519854_520652_+\|carbon-monoxide-dehydrogenase-subunit-G	gnl\|CDD\|176853	cd05018, CoxG, Carbon monoxide dehydrogenase subunit G (CoxG). CoxG has been shown, in Oligotropha carboxidovorans, to anchor the carbon monoxide (CO) dehydrogenase to the cytoplasmic membrane. The gene encoding CoxG is part of the Cox cluster (coxBCMSLDEFGHIK) located on a low-copy-number, circular, megaplasmid pHCG3. This cluster includes genes encoding subunits of CO dehydrogenase and several accessory components involved in the utilization of CO. This family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	1.65288e-16

>NC_021287.1|WP_016344413.1|506833_507865_+|threonylcarbamoyl-AMP-synthase
MTIHFPSDAQIDEAAALLDAGELVAFPTETVYGLGGDAENPDAIARIYAAKGRPANHPVIVHLAPEADPGYWVRELPADAQKLIDAFWPGPLTLILKRGAHIPAAVSGGQDSVGIRCPSHPVAQQMLSAFHARRHGTGKQGGVAGPSANRFGHVSPTTAQHVRDEFGNGVHVLDGGAADVGIESTILDLSRGFPALLRPGHVGPKQIADVIGVAPRLPDGSDATAPRASGTLKAHYAPRTPLALLPFATIAPLIAAQDRASGRKIALVARASSAGEWAHAANVHFVAAPEDPQSYARDLYGLLRALDRANVERILIEKLPESVEWIAVNDRLGRAAAAFEREE
>NC_021287.1|WP_044041152.1|505611_506799_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MNPHNSPISPILPGAWLGMVGGGQLGRMFCFAAQSMGYRVAVLDPDETSPAGAVADRHIRAAYDDRAALTELGRLCAAISTEFENVPSASLEFLASCTFVSPAASCVAIAQDRVAEKRFIAESGVPVAPHVVIESPQALAALPDEKIAAVLPGILKTARLGYDGKGQVSVRNVQEVRTAYASLSGVPCVLEKRMPLKYEVSVLIARGGDGKSAVFPLAQNVHVNGILAKTVVPAPDAQASLVAQAQDAALTIAAKLGYVGVLCVEFFVLEDGSLIANEMAPRPHNSGHYTVDACATSQFEQQVRAMTGMPLGDTRQHSPAAMLNLLGDIWFDGDKARSPAWAEVAAMPAARLHLYGKEDARRGRKMGHINFTAATLEQARTAARDCARMLHIPLD
>NC_021287.1|WP_016344411.1|505001_505523_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MSEVQTGAHTHDAPLVGVLMGSSSDWDVMKHAVAILQEFGVPYEAKVVSAHRMPDEMFAYAESARARGVRAIIAGAGGAAHLPGMLAAKTTLPVLGVPVASKHLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSLLSVTESRYADALAAFRVRQNQAARDMALPPL
>NC_021287.1|WP_016344410.1|504057_504948_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MSTLYESTIKSLPLLGRGKVRDNYAVGQDKLLIVTTDRLSAFDVVMGEPIPNKGRVLNTMADFWFEKLGHIVPNHNTGIDAASVVAPDEVEQVKGRAVVVKRLEPILVEAVVRGYLAGSGWKDYQATGSVCGVELPPGLQNAQKLPEPIFTPAAKAEMGHHDENITYDEMERRIGTELSATIKRISIQLYKEAAEYAATRGIIIADTKFEFGLDNKGELYLMDEVLTADSSRFWPADGYQVGTNPPSFDKQFVRDWLETQPWKKEPPAPKLPEDVIAKTSEKYQEALQRLTGKTLS
>NC_021287.1|WP_044041151.1|502866_503931_+|fructose-bisphosphate-aldolase-class-II
MPLVSMRQLLDHAAEHGYALPAFNVNNLEQVQAIMSAADEVNAPVIMQASAGARKYAGEAFLRHLIEAAVESYPHIPVVMHQDHGQSPAVCMAAIRSGFTSVMMDGSLEADGKSVASYEYNVAVSKQVVEFSHAIGVTVEAELGVLGSLETMKGDKEDGHGAEGTMTREQLLTDVEQAADFVRQTQCDALAIAIGTSHGAYKFSKKPTGDILAIDRIREIHQRIPNTHLVMHGSSSVPQELLAEIREFGGDMKETYGVPVEEIQEGIRHGVRKVNIDTDLRLAISGAIRRYLFENPSKFDPRDYLKPAREAAKEICRQRYMQFGCEGMAGKIKPVSLEKIAAKYKSGELAQIVK
>NC_021287.1|WP_044041893.1|501127_502564_+|pyruvate-kinase
MHRATKIVATIGPASTSPDILLQMLQAGLDVVRFNFSHGTADDHRQRAEIVREAARQVGREVAIMADLQGPKIRVGKFENNKTMLVAGNPFILDANCPLGNNERCGLDYKDLPRDLRAGDVLLLNDGLIVLDVTRVIGEEIHTIVKVGGELSNNKGINRQGGGLTAPALTEKDMEDIKTAMSLGADFVAVSFPKNATDMEMARQLANIAGAPYGIKPKMIAKIERAEAIPALQGILDASDGIMVARGDLAVEVGNAAVPALQKRMIRMARESNKLVITATQMMESMIHAPVPTRAEVSDVANAVLDGTDAVMLSAETAAGKYPVTTIETMAAICVEAEKSEESQLDRDFLDRTFTRIDQSIAMGALFTAFHLGAKAVVALTESGSTALWMSRHWTHVPIFALTPRVGSERTMALYRNVTPLHVDTNMDRDAALNQALEVVVAKGYAARGDMVVLTVGEPMGQAGGTNTLKIVRVGDHF
>NC_021287.1|WP_016344407.1|499590_500787_+|phosphoglycerate-kinase
MTKVLRFTDLIAEGKVSGKRVFIRADLNVPQDDAGNITEDTRVRASVPAIRAALDAGAAVMVTSHLGRPTEGQFKPEDSLAPVAKRLSELLGRDVPLVANWVDGVNVQPGNVVLLENCRCNKGEKKNDDGLAQKLAKLCDIYVNDAFGTAHRAEATTHGIAKYAPVACAGPLLAAELDALGKALGNPKRPLVAIVAGSKVSTKLTILKSLAEKVDQLIVGGGIANTFMLASGLKIGKSLAEADLVGEAKEIIEQARTRGASVPIPSDVVTAKEFAPTAKAETKPVADVADDDLILDIGPDTARALAAQLETAGTIVWNGPVGVFEFDQFGNGTKTLAQAIAGSSAFSIAGGGDTLAAIAKYDIADKVSYISTGGGAFLEFLEGKTLPAVEVLESRAGA
>NC_021287.1|WP_016344405.1|498838_499162_+|AzlD-domain-containing-protein
MSAWQIWLALIGMGLVTAVTRALFLIGGERMVLPPRVQRVLRYAPAAALAAVVVPDLLETPAGVSLALSNHALWASAAGLAYYLWRRGMMGTIAVGMIVFTLLRLAT
>NC_021287.1|WP_051180370.1|498062_498842_+|AzlC-family-ABC-transporter-permease
MLDRLSDTNRRAFFEGVRTFSPAVLATFSWGLVTGIAMTKSVLTVPQALGMSFLVYAGSSQLAVLPLFAAKLPLWTILLTAAMVNLRFVIFSAGLAPHFSYLPLKRRLLLGYFNGDIIYLMFSKQNFATGWQPGKEAFFWGLAVSSWSSWQASSVIGILLASLIPDNWGLELAGTLALIPLIVSAVATRSTLAAVAVASVVALMAFDLPYRFGLPLAVFAALVAGTLADVIAERARPQPAAPEEEPGTKSKSDATRSVR
>NC_021287.1|WP_044041150.1|496805_497726_-|branched-chain-amino-acid-transaminase
MSMADRDGKIWMDGKLIDWRDAKIHVLTHTLHYGMGVFEGVRAYKTAQGTAIFRLKEHTKRLFNSAKIFQMEVPFDHATLEAAQLEVVRENKLESCYIRPIIWVGSEKLGVSAKGNTIHVAIAAWPWGAYLGEDGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQEAVADGYDEALLLDVDGYVSEGSGENFFLVNNGKIYTPDLASCLDGITRDTVITLARDFGIPVIEKRITRDEVYTCDEAFFTGTAAEVTPIRELDNRTIGEGKRGPITEKLQSAFFDVVGGKNEKYASWLAKV
>NC_021287.1|WP_016344414.1|508900_510007_-|hypothetical-protein
MMKQRSTRATLVRLAQFATASAAFALLAACGGGGDDNNSTPAGGVKLQVVSFGDSLSDVGTYAPVAASNFGGGRFTTNPGQVWTQNVAQYYGDTLKPAMTGGFGTAPAVQSGLGYAQGGSRVTNPIGIGHATTDPNNFTGTLTVPVAQQLTNYLASHGSFNAGQLVIVNGGANDILFNLQAVQAGQMTPAAATAAIGQAAIDLAGVIGKVVQNGATHVLVSNVPDIGTTPQGMMSSPTSRALLSQASLGFNQALAAALTQTGLMSKVIYLDIVPPLANITANAAQFGFTVSNTGTACNLQAMAAAAQKFGEPNPQAFATSLFCSPDTLTVAGADQTYMYADTVHPTTHLHALYAQTAEQTIAKSGLGK
>NC_021287.1|WP_016344416.1|510278_511886_-|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase
MPLAFQSVSRRLSSFTLCALLACAALGHAPDTQARGGTKAESQAQAPERAARGGSKAKHAAKSAKAERAAKASVPVGPLPASVMTALARAHVPLSSMSVVVQRVGGPVPLVAINADTPMLPASTMKLVTTYAGLSILGPDYRWKTTAYADGQIDPQGVLHGNLYIQGTGDPKLVPEELIDLVDQIRKSGITGIDGALVLDKRYFDASTRDLPAFDNDDSAPYNVGPDPLLYAFKSLSFTLTPSPDGQVAIDVLPQLAQLQIDNELRVTRGACVGSLSAASPSVAQTQGGFVQASFIGDYPLRCGSRTINVAALDHSTFFAGGFLALWKQAGGTFEGTTREGPTPSGARLVGTHRSPVLSDVVRDINKFSNNVMARNLFLTIGAAQLKPPATTAKSAQAIQAFLRRSALPMDGLSLDNGSGLSRDESISALSLAELLVAANASPVAQVFVESLPIAGVDGTMRNRLTNAGALGNAHIKTGTLRDVRAIAGYVGAANGESYVVVSFINDPRAEAARAAHDALLEWVYEGARKPGVEE
>NC_021287.1|WP_016344417.1|512115_512778_+|response-regulator
MRILLVEDDRMIAEGVRKALRADGFAVDWVQDGEAALTAVTGESYDLMLLDLGLPKRDGLDVLKTLRARANALPVLIVTARDAIADRVKGLDAGADDYLVKPFDLDELGARMRALIRRHAGRGESLVRHGELTLDPVGHQVTLAGAPVSLSAREFALLEALMARPGAVLSKSQLEEKIYGWGEEIGSNTVEVYIHSLRKKLGADLIRNVRGLGYMVAKDA
>NC_021287.1|WP_016344418.1|512777_514079_+|two-component-sensor-histidine-kinase
MRSIRRQLLIWLLALVIVGVGFAGWLIYRQALAEANELFDYQLQQIAAALPSEPFSSVLTSRSESDEGVVIQIWNRNGVLMYYSHPRVPLAPHAELGFSTEMTPRGEWRVYSAIVGDNVVQLAQPLSIRNRVAAGVAWRTLWPLVLLLPLLGLAIWVIVGLGLAPLQRVTRALDTRHPEALDPLSDQRLPQEVQPVVRALNALLSRLSAALDTQKAFVADAAHELRTPLAAVQIQAQLVARAQDDASRREALADLHEGVARATRLAEQLLALARSEPDGKGVTTTVDLRALLETCVRGYVLVAQERGVDLGIEASEPASVTGDPDALRVMFNNLIDNATKYTPKGGRVDVVLTIQNGRPTVEIADNGPGIPQEEREKVFDRFYRVGEGAGRARTDIAGSGLGLAIVRRVADQHAATVSLTQSQAGGLSASIRF
>NC_021287.1|WP_016344419.1|515945_516752_+|OmpA-family-protein
MQQSNAYTNQQISIVRKQMSSVYNDAAARALNNGRHFIDGSVPFKPIYGEKQWPSQQARPKWVQALQQIDVTNQRAAKSSCRGEDAGRLSALTDEAWKEQDETHGTHWVHGWDAIERAQKLAQKVNAELDQCVPPAAVAPAAPTILEKPVTLAADALFGFDSAKLSPDGEHMADSISKDIIESGAKVNVLRVDGYTDRFGSVEHNRKLSLQRAQTVEKALRARGVIADRFDVSGHGAADPVKSCPGTKATQAVIACLAPNRRVTISAK
>NC_021287.1|WP_016344420.1|517089_518598_+|DegQ-family-serine-endoprotease
MKAKILTRSAVAAAVAVALSAGYVAGHNNVPAPQVIAPAQAAPLMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKQTSARRGQNQVPMDPDDPFYQFFKRFGGMPGFGGGGDGGPGADRPSEGLGSGFIVSSDGYILTNAHVVDNANVVTVKLTDKREYRAKVIGADKQSDVAVLKIDAKDLPVVKIGDPNGSKVGQWVVAIGSPYGFDNTVTSGIISAKSRSLPNENYTPFIQTDVPVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDALIKTGHVDRGRLGVTVQGMNQTLANSFGMKSPQGALVSSVEAGGPAAKGGLQPGDVITALNGVPVSDSTSLPSQVAGLAPGTSAKVTVWRDKGAKDLSVTIGALKDAKTASAKAGADDGASAQDARLGVAVRPLTPDEKQSDSLSRGLLVQQSNGAAASAGIQAGDVILAVNGQPVTSVQQLKSMVSHAGDSIALLIQRDDAQIFVPVDLS
>NC_021287.1|WP_016344421.1|518753_519239_+|hypothetical-protein
MTSKTTGKLAAALLMAALGAGAAGGAWAQASGGTTNDTSSAGNTNGGGLPQIQQQGDVSYTSGGVGLDESRALLREQANWPLSLRFTGPTADYLAGVHVRIVGGAGGAEVLNVESMGPYMLVKLPPGNYTVYAKYKDQEKKQAVSVAGPGKAKAAFHWSIQ
>NC_021287.1|WP_016344422.1|519401_519779_+|DUF427-domain-containing-protein
MGTDLNDGHEAAHRIEIALNGRRCRVIHQGVTYADTHASFTVIESGAENAHYFPRADVNMARLERSTHTSHCPHKGEATHYHLLTEDGPVENAAWSYESPLDAAAKIRGYLAFYPTRVDRIDETS
>NC_021287.1|WP_016344423.1|519854_520652_+|carbon-monoxide-dehydrogenase-subunit-G
MEVTDAFRVPLDPAHVREALGDLALVRASPDNCETFTRSPLGEYALTLILPLGALRARYEIRAHSAGRTRRAAHTEGEDDAGSADAEPAYARTLSFKARGEGVGSLRGQIAVSLNPDDEGNGSWIEYTVWATVSGPLAGLPSRQIENALREGADDFFAEFCEVVRAKHGLPSLRAAGDSAARRHVFLRPGSMSAAFSRRPNATRGPADAHASGVLRHRLHGHGFVHHERDHSHDSHPLGLPAWAWAAMLVCVALFAYFAQHVGLQ
>NC_021287.1|WP_173405448.1|520743_521403_+|cysteine-hydrolase
MTMPRRALIVIDVQNEYITGNLPIEYPDVNVSLANIGRAMDAAQKHGVPVVVVQNFAPATAPIFARGSALAELHETVTSRPRAHYVEKALPSAFAGTDLADWLTAHDIDTIVIAGYMTHNCDDSTVRHAVHAGLSVEFLVDATGAVPYENSAGRASAEEIHRVFTVVMQSRFAAVLGTDEWIAALESGEAPARDNIYASNQRARASSSSESASASGGNR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_021287_1	1.11\|508580\|32\|NC_021287\|CRISPRCasFinder	508580-508611	32	NC_011366	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence	442431-442462	6	0.812
NC_021287_1	1.11\|508580\|32\|NC_021287\|CRISPRCasFinder	508580-508611	32	NZ_CP035001	Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence	615674-615705	6	0.812
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_MF133496	Klebsiella pneumoniae strain 675920 plasmid p675920-2, complete sequence	64558-64589	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP031261	Klebsiella quasipneumoniae strain L22 plasmid pL22-4, complete sequence	27920-27951	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP033957	Klebsiella pneumoniae strain L39_2 plasmid p4_L39, complete sequence	59364-59395	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP041095	Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed3, complete sequence	19771-19802	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP041376	Klebsiella pneumoniae strain KP58 plasmid pKP58-3, complete sequence	82935-82966	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP032243	Klebsiella pneumoniae strain XJ-K2 plasmid unnamed3, complete sequence	31075-31106	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP047195	Klebsiella pneumoniae strain Kp36 plasmid unnamed3, complete sequence	47556-47587	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP024461	Klebsiella pneumoniae strain QS17-0161 plasmid pMR0617tem, complete sequence	2932-2963	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP029382	Klebsiella pneumoniae subsp. pneumoniae strain SCKP020079 plasmid pQnrS1_020079, complete sequence	34013-34044	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	AP022370	Klebsiella pneumoniae E328 plasmid pE328_IMP6 DNA, complete sequence	37387-37418	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP028480	Klebsiella pneumoniae strain 2e plasmid unnamed2	22449-22480	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP034126	Klebsiella pneumoniae strain BJCFK909 plasmid p3s1, complete sequence	31677-31708	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP035208	Klebsiella quasipneumoniae strain TH114 plasmid pTH114-3, complete sequence	36547-36578	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP035213	Klebsiella pneumoniae strain TH164 plasmid pTH164-3, complete sequence	36676-36707	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP018341	Klebsiella pneumoniae isolate Kp_Goe_154414 plasmid pKp_Goe_414-4, complete sequence	76619-76650	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	CP050283	Klebsiella pneumoniae strain 9949 plasmid unnamed3, complete sequence	57128-57159	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP054765	Klebsiella pneumoniae strain KP20194b2 plasmid pKP20194b2-p3, complete sequence	31915-31946	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP054747	Klebsiella pneumoniae strain KP20194c4 plasmid pKP20194c4-p3, complete sequence	23289-23320	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP054735	Klebsiella pneumoniae strain KP20194d plasmid pKP20194d-p3, complete sequence	72370-72401	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP054723	Klebsiella pneumoniae strain KP20194f plasmid pKP20194f-p3, complete sequence	12724-12755	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	CP050279	Klebsiella pneumoniae strain 10553 plasmid unnamed4, complete sequence	43147-43178	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP023985	Klebsiella variicola strain X39 plasmid pX39-8, complete sequence	37343-37374	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	CP050288	Klebsiella pneumoniae strain 9630 plasmid unnamed3, complete sequence	12491-12522	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	CP050288	Klebsiella pneumoniae strain 9630 plasmid unnamed3, complete sequence	89961-89992	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_MH341574	Klebsiella pneumoniae strain MYKLB95 plasmid MYKLB95-1, complete sequence	16619-16650	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_MF190368	Klebsiella pneumoniae strain 205880 plasmid p205880-qnrS, complete sequence	50298-50329	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_MG288684	Klebsiella aerogenes strain E20 plasmid pE20-qnrS, complete sequence	60663-60694	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP035205	Klebsiella pneumoniae strain LH94 plasmid pLH94-3, complete sequence	16789-16820	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	MT035876	Klebsiella pneumoniae strain KP18-3-8 plasmid pKP18-3-8-IncFII, complete sequence	33854-33885	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	MT090960	Klebsiella pneumoniae strain KP18-2079 plasmid pKP18-2079_tetA, complete sequence	83760-83791	7	0.781
NC_021287_1	1.6\|508275\|32\|NC_021287\|CRISPRCasFinder	508275-508306	32	NZ_CP033775	Klebsiella pneumoniae strain FDAARGOS_531 plasmid unnamed2, complete sequence	20202-20233	7	0.781
NC_021287_1	1.10\|508519\|32\|NC_021287\|CRISPRCasFinder	508519-508550	32	NZ_CP021031	Rhizobium sp. NXC14 plasmid pRspNXC14a, complete sequence	385821-385852	7	0.781
NC_021287_1	1.5\|508214\|32\|NC_021287\|CRISPRCasFinder	508214-508245	32	NZ_CP019037	Massilia putida strain 6NM-7 plasmid unnamed2, complete sequence	405689-405720	8	0.75
NC_021287_1	1.5\|508214\|32\|NC_021287\|CRISPRCasFinder	508214-508245	32	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	943938-943969	8	0.75
NC_021287_1	1.5\|508214\|32\|NC_021287\|CRISPRCasFinder	508214-508245	32	NC_029005	Streptomyces phage phiSAJS1, complete genome	29864-29895	8	0.75
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	600030-600061	8	0.75
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	213235-213266	8	0.75
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	410365-410396	8	0.75
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	514964-514995	8	0.75
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	KX961385	Bordetella virus LK3, complete genome	478-509	8	0.75
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	KY000220	Bordetella phage FP1, complete genome	36141-36172	8	0.75
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	KY000221	Bordetella phage CN1, complete genome	35647-35678	8	0.75
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	NC_047877	Bordetella phage CN2, complete genome	37243-37274	8	0.75
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	NC_047879	Bordetella phage MW2, complete genome	35952-35983	8	0.75
NC_021287_1	1.1\|507970\|32\|NC_021287\|CRISPRCasFinder	507970-508001	32	NZ_CP041205	Rhizobium sp. NIBRBAC000502774 plasmid pMK-2, complete sequence	375094-375125	9	0.719
NC_021287_1	1.1\|507970\|32\|NC_021287\|CRISPRCasFinder	507970-508001	32	NC_015184	Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence	227622-227653	9	0.719
NC_021287_1	1.4\|508153\|32\|NC_021287\|CRISPRCasFinder	508153-508184	32	NZ_CP013369	Burkholderia ubonensis strain RF23-BP41 plasmid pRF23, complete sequence	209124-209155	9	0.719
NC_021287_1	1.4\|508153\|32\|NC_021287\|CRISPRCasFinder	508153-508184	32	NZ_CP013415	Burkholderia ubonensis strain MSMB2035 plasmid pMSMB2035, complete sequence	250289-250320	9	0.719
NC_021287_1	1.4\|508153\|32\|NC_021287\|CRISPRCasFinder	508153-508184	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1050727-1050758	9	0.719
NC_021287_1	1.5\|508214\|32\|NC_021287\|CRISPRCasFinder	508214-508245	32	NZ_CP047174	Rathayibacter sp. VKM Ac-2760 plasmid unnamed1, complete sequence	85042-85073	9	0.719
NC_021287_1	1.5\|508214\|32\|NC_021287\|CRISPRCasFinder	508214-508245	32	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1662557-1662588	9	0.719
NC_021287_1	1.10\|508519\|32\|NC_021287\|CRISPRCasFinder	508519-508550	32	NC_009339	Mycolicibacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence	302637-302668	9	0.719
NC_021287_1	1.10\|508519\|32\|NC_021287\|CRISPRCasFinder	508519-508550	32	NZ_CP020813	Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed4, complete sequence	26068-26099	9	0.719
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	NZ_LN831789	Streptomyces leeuwenhoekii strain type strain (C34 = DSM 42122 = NRRL B-24963) plasmid pSLE2	106250-106281	9	0.719
NC_021287_1	1.13\|508702\|32\|NC_021287\|CRISPRCasFinder	508702-508733	32	MH153807	Rhodococcus phage Peregrin, complete genome	43549-43580	9	0.719
NC_021287_1	1.19\|508213\|33\|NC_021287\|CRT	508213-508245	33	NZ_CP019037	Massilia putida strain 6NM-7 plasmid unnamed2, complete sequence	405688-405720	9	0.727
NC_021287_1	1.5\|508214\|32\|NC_021287\|CRISPRCasFinder	508214-508245	32	NC_025427	Rhizobium phage vB_RleM_PPF1, complete genome	48277-48308	10	0.688
NC_021287_1	1.5\|508214\|32\|NC_021287\|CRISPRCasFinder	508214-508245	32	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	378958-378989	10	0.688
NC_021287_1	1.5\|508214\|32\|NC_021287\|CRISPRCasFinder	508214-508245	32	MN586033	Corynebacterium phage EmiRose, complete genome	21836-21867	10	0.688
NC_021287_1	1.19\|508213\|33\|NC_021287\|CRT	508213-508245	33	NC_025427	Rhizobium phage vB_RleM_PPF1, complete genome	48277-48309	10	0.697

1. spacer 1.11|508580|32|NC_021287|CRISPRCasFinder matches to NC_011366 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence) position: , mismatch: 6, identity: 0.812

-gccgtgcgcttgaatatcagcctgcccgagca	CRISPR spacer
ggccgc-cgctcgaatagcagcctgcccgacct	Protospacer
 ****. ****.***** ************ *

2. spacer 1.11|508580|32|NC_021287|CRISPRCasFinder matches to NZ_CP035001 (Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence) position: , mismatch: 6, identity: 0.812

-gccgtgcgcttgaatatcagcctgcccgagca	CRISPR spacer
ggccgc-cgctcgaatagcagcctgcccgacct	Protospacer
 ****. ****.***** ************ *

3. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_MF133496 (Klebsiella pneumoniae strain 675920 plasmid p675920-2, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

4. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP031261 (Klebsiella quasipneumoniae strain L22 plasmid pL22-4, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

5. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP033957 (Klebsiella pneumoniae strain L39_2 plasmid p4_L39, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

6. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP041095 (Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

7. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP041376 (Klebsiella pneumoniae strain KP58 plasmid pKP58-3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

8. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP032243 (Klebsiella pneumoniae strain XJ-K2 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

9. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP047195 (Klebsiella pneumoniae strain Kp36 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

10. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP024461 (Klebsiella pneumoniae strain QS17-0161 plasmid pMR0617tem, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

11. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP029382 (Klebsiella pneumoniae subsp. pneumoniae strain SCKP020079 plasmid pQnrS1_020079, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

12. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to AP022370 (Klebsiella pneumoniae E328 plasmid pE328_IMP6 DNA, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

13. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP028480 (Klebsiella pneumoniae strain 2e plasmid unnamed2) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

14. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP034126 (Klebsiella pneumoniae strain BJCFK909 plasmid p3s1, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

15. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP035208 (Klebsiella quasipneumoniae strain TH114 plasmid pTH114-3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

16. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP035213 (Klebsiella pneumoniae strain TH164 plasmid pTH164-3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

17. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP018341 (Klebsiella pneumoniae isolate Kp_Goe_154414 plasmid pKp_Goe_414-4, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

18. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to CP050283 (Klebsiella pneumoniae strain 9949 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

19. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP054765 (Klebsiella pneumoniae strain KP20194b2 plasmid pKP20194b2-p3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

20. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP054747 (Klebsiella pneumoniae strain KP20194c4 plasmid pKP20194c4-p3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

21. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP054735 (Klebsiella pneumoniae strain KP20194d plasmid pKP20194d-p3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

22. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP054723 (Klebsiella pneumoniae strain KP20194f plasmid pKP20194f-p3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

23. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to CP050279 (Klebsiella pneumoniae strain 10553 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

24. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP023985 (Klebsiella variicola strain X39 plasmid pX39-8, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

25. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to CP050288 (Klebsiella pneumoniae strain 9630 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

26. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to CP050288 (Klebsiella pneumoniae strain 9630 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

27. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_MH341574 (Klebsiella pneumoniae strain MYKLB95 plasmid MYKLB95-1, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

28. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_MF190368 (Klebsiella pneumoniae strain 205880 plasmid p205880-qnrS, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

29. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_MG288684 (Klebsiella aerogenes strain E20 plasmid pE20-qnrS, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

30. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP035205 (Klebsiella pneumoniae strain LH94 plasmid pLH94-3, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

31. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to MT035876 (Klebsiella pneumoniae strain KP18-3-8 plasmid pKP18-3-8-IncFII, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

32. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to MT090960 (Klebsiella pneumoniae strain KP18-2079 plasmid pKP18-2079_tetA, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

33. spacer 1.6|508275|32|NC_021287|CRISPRCasFinder matches to NZ_CP033775 (Klebsiella pneumoniae strain FDAARGOS_531 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

----gatggcgatttgatgagggtgcgagcgcgttg	CRISPR spacer
ccgacatgg----ttgatgagggtgcgagcgggatg	Protospacer
     ****    ****************** * **

34. spacer 1.10|508519|32|NC_021287|CRISPRCasFinder matches to NZ_CP021031 (Rhizobium sp. NXC14 plasmid pRspNXC14a, complete sequence) position: , mismatch: 7, identity: 0.781

ctgcg-cgacttccagttcatgccgctgaacgt	CRISPR spacer
-tacacctgctcccagttcatgccgctgaacga	Protospacer
 *.*. * .**.********************

35. spacer 1.5|508214|32|NC_021287|CRISPRCasFinder matches to NZ_CP019037 (Massilia putida strain 6NM-7 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

aagaaggccgccgcccatgacggcgtacaggt	CRISPR spacer
gcgcccggcgccgcgcatgacggcgtccaggt	Protospacer
. *   * ****** *********** *****

36. spacer 1.5|508214|32|NC_021287|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

aagaaggccgccgcccatgacggcgtacaggt	CRISPR spacer
aggtaggccaccgcccatgccggcgtaggcga	Protospacer
*.* *****.********* ******* . *

37. spacer 1.5|508214|32|NC_021287|CRISPRCasFinder matches to NC_029005 (Streptomyces phage phiSAJS1, complete genome) position: , mismatch: 8, identity: 0.75

aagaaggccgccgcccatgacggcgtacaggt	CRISPR spacer
cacctggccgccgtccatgacggtgtacccgt	Protospacer
 *   ********.*********.****  **

38. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 8, identity: 0.75

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
ttggcgaagttgtagccgcgcaggtcgacgcg	Protospacer
. * .**. ************* ** ******

39. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 8, identity: 0.75

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
ttggcgaagttgtagccgcgcaggtcgacgcg	Protospacer
. * .**. ************* ** ******

40. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 8, identity: 0.75

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
ttggcgaaattgtagccgcgcaggtcgacgcg	Protospacer
. * .**. ************* ** ******

41. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 8, identity: 0.75

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
ttggcgaagttgtagccgcgcaggtcgacgcg	Protospacer
. * .**. ************* ** ******

42. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to KX961385 (Bordetella virus LK3, complete genome) position: , mismatch: 8, identity: 0.75

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
aactcaggcttgtaggcgcgcatgtaggcgag	Protospacer
 * *...******** ***********.** *

43. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to KY000220 (Bordetella phage FP1, complete genome) position: , mismatch: 8, identity: 0.75

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
aactccggcttgtaggcgcgcatgtaggcgag	Protospacer
 * *. .******** ***********.** *

44. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to KY000221 (Bordetella phage CN1, complete genome) position: , mismatch: 8, identity: 0.75

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
aactcaggcttgtaggcgcgcatgtaggcgag	Protospacer
 * *...******** ***********.** *

45. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to NC_047877 (Bordetella phage CN2, complete genome) position: , mismatch: 8, identity: 0.75

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
aactcaggcttgtaggcgcgcatgtaggcgag	Protospacer
 * *...******** ***********.** *

46. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to NC_047879 (Bordetella phage MW2, complete genome) position: , mismatch: 8, identity: 0.75

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
aactcaggcttgtaggcgcgcatgtaggcgag	Protospacer
 * *...******** ***********.** *

47. spacer 1.1|507970|32|NC_021287|CRISPRCasFinder matches to NZ_CP041205 (Rhizobium sp. NIBRBAC000502774 plasmid pMK-2, complete sequence) position: , mismatch: 9, identity: 0.719

caatgattgcaccgcctgatgcg---ggtcaggat	CRISPR spacer
caatgacttcaccgcctgatgcgcgaagccga---	Protospacer
******.* **************   .*.*..

48. spacer 1.1|507970|32|NC_021287|CRISPRCasFinder matches to NC_015184 (Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence) position: , mismatch: 9, identity: 0.719

caatgattgcaccgcctgatgcg---ggtcaggat	CRISPR spacer
caatgacttcaccgcctgatgcgcgaagccga---	Protospacer
******.* **************   .*.*..

49. spacer 1.4|508153|32|NC_021287|CRISPRCasFinder matches to NZ_CP013369 (Burkholderia ubonensis strain RF23-BP41 plasmid pRF23, complete sequence) position: , mismatch: 9, identity: 0.719

gcgtcgtccgactccttcagtgcgggcgtcgg	CRISPR spacer
gtgtcgtccgactcctgcagggcggcgatttc	Protospacer
*.************** *** ****  .*.

50. spacer 1.4|508153|32|NC_021287|CRISPRCasFinder matches to NZ_CP013415 (Burkholderia ubonensis strain MSMB2035 plasmid pMSMB2035, complete sequence) position: , mismatch: 9, identity: 0.719

gcgtcgtccgactccttcagtgcgggcgtcgg	CRISPR spacer
gtgtcgtccgactcctgcagggcggcgatttc	Protospacer
*.************** *** ****  .*.

51. spacer 1.4|508153|32|NC_021287|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.719

gcgtcgtccgactccttcagtgcgggcgtcgg--	CRISPR spacer
tcgtcgtccggctccttcagggc--gcactgatc	Protospacer
 *********.********* **  **...*.

52. spacer 1.5|508214|32|NC_021287|CRISPRCasFinder matches to NZ_CP047174 (Rathayibacter sp. VKM Ac-2760 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

aagaaggccgccgcccatgacggc-----gtacaggt	CRISPR spacer
cagaaggccgccgccgattacggccgcctcta-----	Protospacer
 ************** ** *****      **

53. spacer 1.5|508214|32|NC_021287|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 9, identity: 0.719

aagaaggccgccgcccatgacggcgtacaggt	CRISPR spacer
ttgaaagccgccgcccatgacgccgaagcaga	Protospacer
  ***.**************** ** *  .*

54. spacer 1.10|508519|32|NC_021287|CRISPRCasFinder matches to NC_009339 (Mycolicibacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence) position: , mismatch: 9, identity: 0.719

ctgcgcgacttccagttcatgccgctgaacgt	CRISPR spacer
acgcgcgacttccagttcattcagcacagtga	Protospacer
 .****************** * **  *..*

55. spacer 1.10|508519|32|NC_021287|CRISPRCasFinder matches to NZ_CP020813 (Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.719

ctgcgcgacttccagttcatgccgctgaacgt	CRISPR spacer
acgcgcgacttccagttcattcagcacagtga	Protospacer
 .****************** * **  *..*

56. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to NZ_LN831789 (Streptomyces leeuwenhoekii strain type strain (C34 = DSM 42122 = NRRL B-24963) plasmid pSLE2) position: , mismatch: 9, identity: 0.719

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
tcgttgaggttgtagccgcgcaggtcgtggat	Protospacer
. ****** ************* ** *  *

57. spacer 1.13|508702|32|NC_021287|CRISPRCasFinder matches to MH153807 (Rhodococcus phage Peregrin, complete genome) position: , mismatch: 9, identity: 0.719

cagttgagcttgtagccgcgcatgtagacgcg	CRISPR spacer
gcctagagcttgtaaacgcgcatgtagatatg	Protospacer
   * *********. ************...*

58. spacer 1.19|508213|33|NC_021287|CRT matches to NZ_CP019037 (Massilia putida strain 6NM-7 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.727

caagaaggccgccgcccatgacggcgtacaggt	CRISPR spacer
tgcgcccggcgccgcgcatgacggcgtccaggt	Protospacer
.. *   * ****** *********** *****

59. spacer 1.5|508214|32|NC_021287|CRISPRCasFinder matches to NC_025427 (Rhizobium phage vB_RleM_PPF1, complete genome) position: , mismatch: 10, identity: 0.688

aagaaggccgccgcccatgacggcgtacaggt	CRISPR spacer
gtcgcagccgccgcccatgccggcgaacagaa	Protospacer
.  . .************* ***** ****.

60. spacer 1.5|508214|32|NC_021287|CRISPRCasFinder matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 10, identity: 0.688

aagaaggccgccgcccatgacggcgtacaggt	CRISPR spacer
ctcaagcccgccgcccatgtcggcgttgcttt	Protospacer
   *** ************ ******     *

61. spacer 1.5|508214|32|NC_021287|CRISPRCasFinder matches to MN586033 (Corynebacterium phage EmiRose, complete genome) position: , mismatch: 10, identity: 0.688

aagaaggccgccgcccatgacggcgtacaggt	CRISPR spacer
agcggcctggccgcccatgacggcgtgcatgt	Protospacer
*. ..  . *****************.** **

62. spacer 1.19|508213|33|NC_021287|CRT matches to NC_025427 (Rhizobium phage vB_RleM_PPF1, complete genome) position: , mismatch: 10, identity: 0.697

caagaaggccgccgcccatgacggcgtacaggt	CRISPR spacer
cgtcgcagccgccgcccatgccggcgaacagaa	Protospacer
*.  . .************* ***** ****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

591632 : 600906

Streptococcus_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016344481.1\|591632_593738_-	elongation factor G	E4ZFJ7	Streptococcus_phage	7.5e-56	26.5
WP_144063308.1\|593976_594492_-	DUF192 domain-containing protein	A0A222YVT9	Synechococcus_phage	3.0e-14	42.2
WP_016344483.1\|594690_594906_-	hypothetical protein	NA	NA	NA	NA
WP_016344484.1\|595297_595873_-	pseudouridine synthase	NA	NA	NA	NA
WP_016344486.1\|596122_597379_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	7.5e-11	61.1
WP_016344487.1\|597561_597768_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	2.0e-22	77.3
WP_016344488.1\|598291_598606_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	5.8e-13	43.4
WP_016344489.1\|598602_600906_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-168	42.2

DBSCAN-SWA_2

2136459 : 2144861

Yaba-like_disease_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044041472.1\|2136459_2137353_+	alpha/beta hydrolase	Q9DHU9	Yaba-like_disease_virus	2.3e-22	28.9
WP_016345959.1\|2137349_2138273_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	1.4e-43	37.9
WP_016345961.1\|2138616_2139789_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_016345962.1\|2139872_2140775_-	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	5.3e-51	39.9
WP_016345963.1\|2141047_2141443_-	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_016345964.1\|2141517_2142510_-	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	2.6e-30	33.3
WP_051180333.1\|2142517_2143492_-	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.4e-12	25.7
WP_016345966.1\|2143457_2144861_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A1B1IU65	uncultured_Mediterranean_phage	1.3e-16	26.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_021289

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_021294

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_021288

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. NC_021287

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection