CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP011992	Klebsiella pneumoniae UHKPC33 plasmid pUHKPC33-43.380kb, complete sequence	0 crisprs	NA	0	1
NZ_CP011989	Klebsiella pneumoniae UHKPC33 chromosome, complete genome	2 crisprs	csa3,cas3,DEDDh,RT,DinG,WYL	1	11
NZ_CP011993	Klebsiella pneumoniae UHKPC33 plasmid pUHKPC33-13.841kb, complete sequence	0 crisprs	NA	0	0
NZ_CP011991	Klebsiella pneumoniae UHKPC33 plasmid pUHKPC33-113.638kb, complete sequence	0 crisprs	NA	0	6
NZ_CP011990	Klebsiella pneumoniae UHKPC33 plasmid pUHKPC33-162.533kb, complete sequence	0 crisprs	cas3,RT	0	4

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

3248 : 13546

Escherichia_phage(50.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000516402.1\|3248_3911_-	peptidyl-arginine deiminase	E5FFJ3	Burkholderia_phage	2.6e-07	25.2
WP_001549893.1\|4291_4954_+	recombinase family protein	M9Q1K0	Clostridium_phage	9.7e-10	29.1
WP_001549892.1\|5040_5280_+	hypothetical protein	I6PD82	Cronobacter_phage	4.4e-21	55.1
WP_001067855.1\|5672_6377_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_002904004.1\|6513_7374_+	class A extended-spectrum beta-lactamase SHV-12	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_002210513.1\|7394_8156_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_002903955.1\|8417_9320_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
WP_004199413.1\|10528_13546_-\|transposase	Tn3-like element IS3000 family transposase	A0A125RQ78	Bacillus_phage	5.5e-52	24.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP011989

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011989_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011989_1

3998469-3998564

Orphan

Consensus_repeat	Method
TGGCACTTTGTTGGCATTCTGTTGGCACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011989_1

>merge|NZ_CP011989|1|3998469-3998564|CRISPRCasFinder
TGGCACTTTGTTGGCATTCTGTTGGCACAACCTCGCCGGTACGCAGCGTGGTTACTGGGTTTGCGTTGGCACTTTGTTGGCATTCTGTTGGCACAA

>NZ_CP011989|1|1|3998469-3998564|CRISPRCasFinder
TGGCACTTTGTTGGCATTCTGTTGGCACAA	CCTCGCCGGTACGCAGCGTGGTTACTGGGTTTGCGT
TGGCACTTTGTTGGCATTCTGTTGGCACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011989.1\|WP_004151300.1\|3999805_4000495_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NZ_CP011989.1\|WP_004151291.1\|3994073_3994721_-\|DUF551-domain-containing-protein	unknown	unknown	gnl\|CDD\|367946
NZ_CP011989.1\|WP_004151293.1\|3994893_3995736_-\|ead/Ea22-like-family-protein	unknown	unknown	gnl\|CDD\|379401
NZ_CP011989.1\|WP_001548453.1\|3999182_3999404_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|336083
NZ_CP011989.1\|WP_004151299.1\|3999444_3999678_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|374243
NZ_CP011989.1\|WP_004151301.1\|4000845_4001061_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011989.1\|WP_004151285.1\|3992185_3992323_-\|YlcG-family-protein	unknown	unknown	unknown
NZ_CP011989.1\|WP_004151306.1\|4002585_4003266_+\|YqaJ-viral-recombinase-family-protein	unknown	unknown	gnl\|CDD\|378216
NZ_CP011989.1\|WP_004151286.1\|3992319_3992955_-\|recombination-protein-NinG	unknown	unknown	gnl\|CDD\|368603
NZ_CP011989.1\|WP_004151295.1\|3996345_3996639_-\|protein-ren	unknown	unknown	gnl\|CDD\|238042
NZ_CP011989.1\|WP_004151303.1\|4001160_4001355_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011989.1\|WP_004151304.1\|4001443_4001728_+\|host-nuclease-inhibitor-GamL	unknown	unknown	unknown
NZ_CP011989.1\|WP_004151305.1\|4001743_4002589_+\|phage-recombination-protein-Bet	unknown	unknown	gnl\|CDD\|273871
NZ_CP011989.1\|WP_004151292.1\|3994717_3994894_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011989.1\|WP_004151287.1\|3992947_3993118_-\|NinE-family-protein	unknown	unknown	gnl\|CDD\|182029
NZ_CP011989.1\|WP_004151302.1\|4001057_4001168_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011989.1\|WP_004151294.1\|3995842_3996349_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011989.1\|WP_004151298.1\|3998950_3999097_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011989.1\|WP_004151288.1\|3993117_3993573_-\|YbcN-family-protein	unknown	unknown	gnl\|CDD\|182057
NZ_CP011989.1\|WP_004230547.1\|3996638_3998054_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274672

Protein	Function_ID	Function_description	E-value
NZ_CP011989.1\|WP_004151300.1\|3999805_4000495_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	1.58097e-27
NZ_CP011989.1\|WP_004151291.1\|3994073_3994721_-\|DUF551-domain-containing-protein	gnl\|CDD\|367946	pfam04448, DUF551, Protein of unknown function (DUF551). This family represents the carboxy terminus of a protein of unknown function, found in dsDNA viruses with no RNA stage, including bacteriophages lambda and P22, and also in some Escherichia coli prophages.	8.71432e-11
NZ_CP011989.1\|WP_004151293.1\|3994893_3995736_-\|ead/Ea22-like-family-protein	gnl\|CDD\|379401	pfam13935, Ead_Ea22, Ead/Ea22-like protein. This family contains phage proteins and bacterial proteins that are likely to represent integrated phage proteins. This family includes the Lambda phage Ea22 early protein as well as the Bacteriophage P22 Ead protein.	0.000117969
NZ_CP011989.1\|WP_001548453.1\|3999182_3999404_-\|hypothetical-protein	gnl\|CDD\|336083	pfam05269, Phage_CII, Bacteriophage CII protein. This family consists of several phage CII regulatory proteins. CII plays a key role in the lysis-lysogeny decision in bacteriophage lambda and related phages.	1.55058e-09
NZ_CP011989.1\|WP_004151287.1\|3992947_3993118_-\|NinE-family-protein	gnl\|CDD\|182029	PRK09689, PRK09689, prophage protein NinE; Provisional.	1.47696e-19
NZ_CP011989.1\|WP_004151306.1\|4002585_4003266_+\|YqaJ-viral-recombinase-family-protein	gnl\|CDD\|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	1.68114e-32
NZ_CP011989.1\|WP_004151295.1\|3996345_3996639_-\|protein-ren	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	0.000668668
NZ_CP011989.1\|WP_004151305.1\|4001743_4002589_+\|phage-recombination-protein-Bet	gnl\|CDD\|273871	TIGR01913, Uncharacterized_protein_UU154, phage recombination protein Bet. This model represents the phage recombination protein Bet from a number of phage, including phage lambda. All members of this family are found in phage genomes or in putative prophage regions of bacterial genomes. [Mobile and extrachromosomal element functions, Prophage functions].	3.75286e-34
NZ_CP011989.1\|WP_004151299.1\|3999444_3999678_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	9.32854e-22
NZ_CP011989.1\|WP_004151288.1\|3993117_3993573_-\|YbcN-family-protein	gnl\|CDD\|182057	PRK09741, PRK09741, hypothetical protein; Provisional.	1.50704e-78
NZ_CP011989.1\|WP_004151286.1\|3992319_3992955_-\|recombination-protein-NinG	gnl\|CDD\|368603	pfam05766, NinG, Bacteriophage Lambda NinG protein. NinG or Rap is involved in recombination. Rap (recombination adept with plasmid) increases lambda-by-plasmid recombination catalyzed by Escherichia coli's RecBCD pathway.	9.44908e-60
NZ_CP011989.1\|WP_004230547.1\|3996638_3998054_-\|AAA-family-ATPase	gnl\|CDD\|274672	TIGR03600, phage_DnaB, phage replicative helicase, DnaB family, HK022 subfamily. Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions].	9.32956e-159

>NZ_CP011989.1|WP_004230547.1|3996638_3998054_-|AAA-family-ATPase
MTPPHSIEAEQSVLGGLLLDDDNSERTQKVLSILKPESFYARPHQVIFAEMRQMYRDHKPVDLLTLFDALESKGLTETVGGFAYLAEMSKNTPSAANIVAYAMRVRETAMERYGIEKTTKAIELLYARNGMTAEQKFDAIQGLFTEITEHVKTGRRTGLRTFYDAVTDWSAEFDERLKPDGRSRGLSTGIRSLDELLGVKRIVRGSLFVIGARPKMGKTTLYTQMGINCATVENEPALMFSLEMPEGQMVEKITAQKGRISPNLFYPDMTKDDYGYRGDWNSDLQKATGVMGALIETNNLLIDDTPGISLAHVMAESRRIKRERGKVGMILVDYLTLMTADKAERNDLAYGLITKGLKILAKELDCVVVLLTQLNRDLEKRTNKRPLPSDSRDTGQIEQDCDYWLAIYREGAYDENANQSDTELLLRLNRHGETGVVYCEQRHGAIYDCDQEAASQRRREKEQKPTKRGGF
>NZ_CP011989.1|WP_004151295.1|3996345_3996639_-|protein-ren
MTGKDAILNYLKTHKTCSSPDVAAASGMTHTCINQAANILAKQGVLVAEARVWRTVYYRLATEEEIAGRKSTNQIFNECRQSPAMKRVLAVYGRTSA
>NZ_CP011989.1|WP_004151294.1|3995842_3996349_-|hypothetical-protein
MTITLQAVNKLIASMESAGELSIREQKFLKLAKEFRICSASLDAAIKTGNMLADQNAQLAAENVALKDINAWCKTDAFKNMYREFKTAEALGCSDADCMHDAMLVAIMHAPATPATDRIVAGIKADGVEEFAAKLRIPGDDQFFDALAKGIALAADDFAKQLREGADK
>NZ_CP011989.1|WP_004151293.1|3994893_3995736_-|ead/Ea22-like-family-protein
MTDITELAQSLKAAAEKASNGDWVKESGDGWEACCSANDQANGGFIIAHFVGPDAAENCEFVQAANPANVLALVEALEYYKSREERVTSLVRDNSKSWDELYRQVEAKGKRNVELVEALESEKRICATWRKTAESTSEKLEKAQAAERRWHRVASRVHEQACESDVKIDELEAIRAAAEKLVRCKGRYHSEQNYRALAALFGVNTPDLPPLEHENVHYADAAEMEIEALRQRIAELESRTVKLPPRVDSSNVPFAGNAWNCCLDEVEKRLTAAGIKMEAE
>NZ_CP011989.1|WP_004151292.1|3994717_3994894_-|hypothetical-protein
MAERWKIYLTIAFIGLGATPISMVAAKIDVPVWALIAGHCGATIAGFICAELGRGANQ
>NZ_CP011989.1|WP_004151291.1|3994073_3994721_-|DUF551-domain-containing-protein
MTNNQLAENSVIQLLNSVKLARDNAELADNRVDHSFYYALTIALEELQERRKAAMDSEPVLWAWHHLDMWHVTSHDGRARDLWLSGFKVIPLYRHAQPVLVIPDEMTAEQAYEIGYYYGDPVDVFARGANWMRQHIIDSTLAAAPQSPGSDPATVPGKWISVSERMPENDGAYLCWDNRYVTTYAFIFGAWQANQFIAKNITHWMPLPAGPQEVR
>NZ_CP011989.1|WP_004151288.1|3993117_3993573_-|YbcN-family-protein
MNIPQCGIKLHNGNFSAIGKILQEQLSDGKCLRLQVKEWREKRSLSQNALSHMWYAEISEYLINSGRTDATPEWVKRNLKKTYLGCEEVTYTDFITGEKTTTWEPRHTSDLDTGEMHIFLTKVEAWCAQFGLALTIPHGCEYQQLQQKQEA
>NZ_CP011989.1|WP_004151287.1|3992947_3993118_-|NinE-family-protein
MSSLLAKVIERGIFRVPARRKRKVEDKPSDIPTLKDYTARLVDKKWLRLRARRPHA
>NZ_CP011989.1|WP_004151286.1|3992319_3992955_-|recombination-protein-NinG
MRKPARRKCAHCREWFHPAREGQVVCSFECASAIGKKQTAKAREAAKARAVKRQRESEKEGRQRRKARLAELRPNGYYKAQAQKAFNAYIRARDAALPCISCGETNPPDLHGGQWDCGHFKTVGAYPELRFEERNAHKQCKSCNAGAGKYTAKELTVAQQYEAGLVARYGQEYVDWLNGPHEMTNYRREDFIRIRDEYRAKLKALKQREAA
>NZ_CP011989.1|WP_004151285.1|3992185_3992323_-|YlcG-family-protein
MNHDIIERIRDRWKKLRLLRSRGTVLVDYLILRNFIASLSRGSYE
>NZ_CP011989.1|WP_004151298.1|3998950_3999097_-|hypothetical-protein
MPKSNRFYQAQTHKNVTRDRFIRSVNPVVGMKMRAILEELKRKEEGRE
>NZ_CP011989.1|WP_001548453.1|3999182_3999404_-|hypothetical-protein
MESSTTRNKVEARRIESWLHSQIAELGTTNIAKVAGVNKSTVSRWRESLLPNMSLLLAILISNRPGEKGDFEA
>NZ_CP011989.1|WP_004151299.1|3999444_3999678_-|helix-turn-helix-domain-containing-protein
MKNPAVEKAISIAGSQKELAKRCGKAQSTICDWLNGKKRISPVHVPDLVAAVNGEIKAYEFRPDLPSIFPPPNNSAA
>NZ_CP011989.1|WP_004151300.1|3999805_4000495_+|helix-turn-helix-transcriptional-regulator
MDFSERLARAMSLAGYTQGRLAKEVGMAQSSVNKLLNGANGSRKTVEIASVLGVRPEWLSTGAGEMLADSIQITQMQTPVTPQNGIYRVDVLDVKASAGPGALITNDFIETIRAIEYTSEQARSLFGNRPAHHIKVITVTGDSMDTTISPGDEIFVDISSTHFDSDGVYVFVFGKTLHVKRLQMQRDRLAVISDNPIYEKWYVEPGDEDQFYVMARVLLRQSIEYKRFA
>NZ_CP011989.1|WP_004151301.1|4000845_4001061_+|hypothetical-protein
MSKENNGGPAYPTQGYEGLTVRDYFAAKAMQGWLAGYPAGINHPARSEEGFTVAELSYLMADAMLKAREEV
>NZ_CP011989.1|WP_004151302.1|4001057_4001168_+|hypothetical-protein
MSKQGIRSLIYCLLICGVIWSAVVIKILHATGVFNG
>NZ_CP011989.1|WP_004151303.1|4001160_4001355_+|hypothetical-protein
MANSIPNNGRAVMMRNRRTGAAWLVSFDYRDGSYWHEPQGNLRHIRRPYASRSIEPNLVPAGTH
>NZ_CP011989.1|WP_004151304.1|4001443_4001728_+|host-nuclease-inhibitor-GamL
MNAYRAYDVIEERKWAEQTLTEEKQKWIEDRAKEVFDSLPEDPYAALRQSVSSKSFPYEGLRSDKAGEVYNDLRTAIAYAQAEYDWDHRTGCPF
>NZ_CP011989.1|WP_004151305.1|4001743_4002589_+|phage-recombination-protein-Bet
MANELVITASSLAERGIDGATWSALKNSIYPGAKDESVMMALDYCRARNLDPLLKPVHLVPMSVKDSKSGKSEWRDVVMPGIGLYRIQADRSGDYAGAKEPEFGPDVTLTLTGIEVTVPQWCKYTVSKRMPSGEIVEFSAKEYWVENYATAGRDTTAPNAMWKKRPYGQLAKCAEAQALRKAWPEIGQQPTAEEMEGKTLEVDARDVTPRSTPEAPPLVASEETLQAITDLLTSLNKDWEQDFLPLCSNIFKRDIFQASQLTEEEAQKGFSFLQKKAQVAA
>NZ_CP011989.1|WP_004151306.1|4002585_4003266_+|YqaJ-viral-recombinase-family-protein
MTPEIILERTGIDVTRVEQGDESWHRLRLGVITASEVHNVISKPKSGKKWTDMKMSYFLTLLAEVCTGVAPEVNAKALAWGKQYEADARTLFEFTTDVKVTESPILFRDEGMRTACSPDGLCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQFSMWVTGKDAWYFANYDPRMKREGIHHVVVERDDKYMSDFNEMVPEFISKMDESLAEIGFTFGEQWK

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Crispr_ID: NZ_CP011989_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011989_2

4482439-4482533

Orphan

Consensus_repeat	Method
ACTATGGTTTTTATGGTTTTTATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011989_2

>merge|NZ_CP011989|2|4482439-4482533|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATGGTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATGACTGTGGTTTTTATGGTTTTTATT

>NZ_CP011989|2|2|4482439-4482533|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATG	GTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATG
ACTGTGGTTTTTATGGTTTTTATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011989.1\|WP_002888357.1\|4471557_4473060_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP011989.1\|WP_002888345.1\|4480985_4482350_-\|2-hydroxycarboxylate-transporter-family-protein	unknown	unknown	gnl\|CDD\|377030
NZ_CP011989.1\|WP_004147026.1\|4486091_4488440_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP011989.1\|WP_004151368.1\|4476613_4479520_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP011989.1\|WP_002888332.1\|4485020_4485848_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP011989.1\|WP_002888340.1\|4482674_4484300_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP011989.1\|WP_002888320.1\|4493082_4493562_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP011989.1\|WP_002888370.1\|4468654_4469500_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP011989.1\|WP_002888349.1\|4474068_4476426_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP011989.1\|WP_002888329.1\|4488494_4489781_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP011989.1\|WP_002888373.1\|4467758_4468526_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP011989.1\|WP_002888348.1\|4479532_4480192_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP011989.1\|WP_002888321.1\|4491978_4492827_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)-ApaH	unknown	unknown	gnl\|CDD\|273208
NZ_CP011989.1\|WP_002888353.1\|4473197_4473893_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP011989.1\|WP_002888337.1\|4484289_4484988_+\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP011989.1\|WP_002888327.1\|4489786_4490776_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP011989.1\|WP_002888324.1\|4490772_4491594_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP011989.1\|WP_002888347.1\|4480266_4480806_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|163145
NZ_CP011989.1\|WP_002888323.1\|4491596_4491974_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP011989.1\|WP_002888368.1\|4469837_4471547_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221

Protein	Function_ID	Function_description	E-value
NZ_CP011989.1\|WP_002888357.1\|4471557_4473060_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP011989.1\|WP_002888345.1\|4480985_4482350_-\|2-hydroxycarboxylate-transporter-family-protein	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	4.87969e-169
NZ_CP011989.1\|WP_004147026.1\|4486091_4488440_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP011989.1\|WP_004151368.1\|4476613_4479520_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP011989.1\|WP_002888332.1\|4485020_4485848_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.63694e-164
NZ_CP011989.1\|WP_002888340.1\|4482674_4484300_+\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	6.55037e-173
NZ_CP011989.1\|WP_002888320.1\|4493082_4493562_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.71656e-127
NZ_CP011989.1\|WP_002888370.1\|4468654_4469500_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP011989.1\|WP_002888349.1\|4474068_4476426_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP011989.1\|WP_002888329.1\|4488494_4489781_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP011989.1\|WP_002888373.1\|4467758_4468526_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.35562e-48
NZ_CP011989.1\|WP_002888348.1\|4479532_4480192_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	2.4454e-161
NZ_CP011989.1\|WP_002888321.1\|4491978_4492827_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)-ApaH	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP011989.1\|WP_002888353.1\|4473197_4473893_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	0
NZ_CP011989.1\|WP_002888337.1\|4484289_4484988_+\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	5.03078e-66
NZ_CP011989.1\|WP_002888327.1\|4489786_4490776_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP011989.1\|WP_002888324.1\|4490772_4491594_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.65731e-147
NZ_CP011989.1\|WP_002888347.1\|4480266_4480806_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|163145	TIGR03124, citrate_citX, holo-ACP synthase CitX. Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair].	5.54697e-86
NZ_CP011989.1\|WP_002888323.1\|4491596_4491974_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	7.84855e-74
NZ_CP011989.1\|WP_002888368.1\|4469837_4471547_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0

>NZ_CP011989.1|WP_002888345.1|4480985_4482350_-|2-hydroxycarboxylate-transporter-family-protein
MSTTDNAFSATLEPIDTPKTTLKQRWWHIMDNWKVGIVPLPLFLLAGGLIALDCLGGKLPSDIVVMVATLAFFGFACGEFGKRLPVLGKLGAAAICATFIPSALVHYGLLPDVVIESTTKFYKSTNILYLYICCIIVGSIMSMNRTTLIQGFLKIFFPMLCGEVVGMLVGIGVGTLLGMEPFQVFFFIVLPIMAGGVGEGAIPLSMGYAALMHMEQGVALGRVLPMVMLGSLTAIVISGCLNQLGKRFPHLTGEGQLMPNRSHETRSLSESEGVSGKTDVGTLASGALLAVLLYMMGMLGHKLIGLPAPVGMLFLAVLLKLANVVSPRLQEGSQMVYKFFRTAVTYPILFAVGVAITPWQELVNAFTLTNLLVIVSTVSALVATGFLVGKKIGMHPIDVAIVSCCQSGQGGTGDVAILTAGNRMSLMPFAQIATRIGGAINVSLGLLFLSHYLA
>NZ_CP011989.1|WP_002888347.1|4480266_4480806_-|citrate-lyase-holo-[acyl-carrier-protein]-synthase
MSVDTPAQAGVSIDALLAAKEQRAARQADWLAHYQQPVISLTLVTPGAVKDSIRYRNMMGVALQACDQLLWKHRWQTLDRQVLWLPTGPEALWCVAHPASEIKAMCSTLEQSHPLGRLWDIDVICPQNGLVGRQSLGESQRRCLLCDEPAHACARSRRHDTDLVVARVEQMIDAWFARD
>NZ_CP011989.1|WP_002888348.1|4479532_4480192_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MAMENYNPPQDPWLVILYQDEHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDFPQAESVHRLDMATSGVIVVALNKAAERELKRQFREREPKKQYVARVWGHPQPAEGLVDLPLICDWPNRPKQKVCYETGKAAQTEYEVLEYAEDNTARVRLKPITGRSHQLRVHMLALGHPILGDRFYATPEALAMAPRLLLHAETLTITHPAYGNAMTFRAPIDF
>NZ_CP011989.1|WP_004151368.1|4476613_4479520_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESIDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAGIESNRQQVMDALAQAGWRLDALRLIVVTHQ
>NZ_CP011989.1|WP_002888349.1|4474068_4476426_+|DNA-polymerase-II
MTQPRAGFLLTRHWRDTPQGTELSFWLATDDGPLQVTLPPQESVAFIPEAQRAQAERLLQGEKGLRFAPLALKDFHRQPIVGLYCRAHRQLMRLEKMLRDSGVTVYEGDIRPPERYLMERFITAPVWVEGETRGSQLVNARMKPNPDYRPPLKWVSLDIETSRHGELYCIGLEGCGQRVVYMLGPEPETPPDVDFELVFIASRPLLLEKLNAWFAEHDPDVLIGWNVVQFDLRVLQKHAERYRIPLRLGRGNSELEWREHGFKNGVFFAQANGRLIIDGIDALKSAFWNFSSFSLEAVARELLGEGKAIDNPWDRMDEIDRRFHEDKPALAIYNLQDCELVTRIFHKTEIMPFLLERATVNGLPADRHGGSVAAFSHLYFPRMHRLGYVAPNLGDVPPQASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLIEGLAQPDDQHSIEGFLGARFSRDKHCLPGIVSQIWHGRDEAKRQHNKPLSQALKIIMNAFYGVLGTSACRFFDPRLASSITMRGHAIMRQTKALIEAKGYDVIYGDTDSTFVWLKRPHSEAQAAEIGRELVSHVNAWWAQELSKSQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGMIQEGDAQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNQPYQDYVRETIARLMNGELDEQLVYRKRLRRPLAEYQRNVPPHVRAARLADEHNLKLGRAQQYQQRGTIKYVWTTSGPEPVDYQQSPLDYDHYLTKQLQPVAEGILPFVNDDFATIVTGQLGLF
>NZ_CP011989.1|WP_002888353.1|4473197_4473893_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDREKGVFVIKPSGVDYRVMTADDMVVVSLESGEVVEGNKKPSSDTPTHRLLYQAFPTLGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGPVPCTRLMTDAEINGDYEWETGNVIVETFRQQGIDPAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEIAYMGIFCRQLAPQLPAMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP011989.1|WP_002888357.1|4471557_4473060_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPEALRQVTKHAEHVVNSLNAEAKLPCKLVLKPLGTTPDEITHICRDANYDDKCAGLVVWLHTFSPAKMWINGLTILNKPLLQFHTQYNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHQRIGGWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDISALVDEYESSYRLTPAAQVHGEKRQNVLDAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFDNGNDLVLGSHMLEVCPTIATVEKPILDVQPLGIGGKADPARLIFNTQTGPAIVASLIDLGDRFRLLVNTIETVPTPHDLPKLPVANALWKAQPDLRTASEAWIIAGGAHHTVFSHALNLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
>NZ_CP011989.1|WP_002888368.1|4469837_4471547_+|ribulokinase
MAIAIGLDFGSDSVRALAVECASGAELATSVEWYPRWREGQYCDGANNRFRHHPRDYIESMEAALKSVLASLSAEQRADVVGIGVDSTGSTPAPVDAEGNVLALREEFADNPNAMFVLWKDHTAVEEAEAITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTREDSAVAQAAASWVELCDWVPALLSGTTRPQDLRRGRCSAGHKSLWHESWGGLPPASFFDELDPIINQHLAWPLFTDTWTADVPVGTLSAEWAQRLGLSQSVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKESVGERTVKGICGQVDGSVVPHFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQQQPALREQIKASQKQLLPALTEAWANNPSLEHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAGVYDDIPAAQQRMASQVETTLQPRPAQAQRFEQLYQRYQQWSVSAEQHYLPSAAKAEKAPQSKAALTH
>NZ_CP011989.1|WP_002888370.1|4468654_4469500_-|arabinose-operon-transcriptional-regulator-AraC
MAETQNDPLLPGYSFNAHLVTGLTPIEAQGYLDFFIDRPLGMKGYILNLTIRGEGVINNHGEQFVCRPGDMLLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWHEWLNWPTIFAQTGFFRPDEQWQARFGELFGQIVDAGQGAGRYSELLAINLLEQLLLRRMEAINESLHPPLDNRVREACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQLGVSVLGWREDQRISQAKLLLSTTRMPIATVGRNVGFEDQLYFSRVFKKCTGASPSEFRAGCE
>NZ_CP011989.1|WP_002888373.1|4467758_4468526_-|DedA-family-protein
MQALLEHFITQSTVYSLLAVMLVAFLESLALVGLILPGTVMMAGLGALIGGGEVNFWQAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFMKKNRALLEKTEHALHQHSMITILIGRFVGPTRPLVPMVAGMLDLPVAKFVLPNIIGCLLWPPLYFLPGILAGAAIDIPADENSASFKWLLLGAALLAWLAGWLCWRLWRSAKTSGDRLTRWLPRGRLLWLSPLMVALAATALTFVFRHPLMPVYLAILHKVIAR
>NZ_CP011989.1|WP_002888340.1|4482674_4484300_+|sensor-histidine-kinase
MKLSFQYKLFISLVAFFSVLFIALGIYYYFDASRQLYQEMSARAKIQAEEIALMPNLRQQVSRHDPQAIQAFMQQIAAHSDASFIVIGDRQGVHLFHSVHPEWVGTRLVGGDNQAVLEGKSITTIRKGGLGVSLRSKTPIVDDAGRVIGIVSVGYLTSYLDSITLTKVINIFIAAVLLLIALFIFSWYFTRSIKKQIFSLEPREIGLLVRQQKAMMESIFEGVIVIDRQRRIEVINHAARSLLGLSQPARQLRGQSIDSVISPQPFFASGDMLERDTHDELCRFNQLTVLASRVRIMLENTLQGWVITFRDRNEINALTAQLSQVKRYVDNLRIMRHEQLNRMTTLSGLLHMGHYDEAIRYIQAQSEHAQELLDFISSHFHSPTLCGLLLGKATRAREKGVALSFDPACRIDRPLPSLMESELISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTRGDHGIGLYLIEHYVTQAGGTIEVADNAPRGTIFTLFIPADAHACPQPEAHDAS
>NZ_CP011989.1|WP_002888337.1|4484289_4484988_+|response-regulator
MHHDLVDVLIIEDESELARLHAELVQKHPRLRLAGMAASLAQARQLLHATPPQLVLLDNYLPDGKGVTLMTDPALATSQCSVIFITAASDMETCSQAIRNGAFDYILKPVSWKRLSQSLERFIQFYDQQREWKIVDQQNVDSLYQLQAKNYRVDSGSKGIEEKTLALVQGLFSDREAHCFSVDEVVSAAGLSKTTARRYLEHGVETGFLEVEMLYGKIGHPRRLYRRAKVKS
>NZ_CP011989.1|WP_002888332.1|4485020_4485848_-|co-chaperone-DjlA
MQYLGKVIGVAVALLMGGGFWGVVLGFLVGHMFDRARSRRLNLFANQQERQSLFFSTTFEVMGHLTKSKGRVTEADIHVANVLMDRMNLHGASRTAAQQAFRDGKADNYPLREKMRQLRSVCFGRFDLIRMFLEIQLQAAFADGELHPNEREVLFVIADELGISRAQFDQFLRMMQGGAQFGGGSQQRSYGQHGGNAGWQQAQRGPTLEDACNVLGVKPTDDAATVKRAYRKLMNEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAWELIKEQRGF
>NZ_CP011989.1|WP_004147026.1|4486091_4488440_+|LPS-assembly-protein-LptD
MKKRIPSLLATMIASALYSQQGLAADLATQCMLGVPSYDRPLVEGRPGDLPVTINADHAKGNYPDNAVFTGNVDINQGNSRLRADEVQLHQQQAAGQAQPVRTVDALGNVHYDDNQVILKGPKAWSNLNTKDTNVWQGDYQMVGRQGRGTADLMKQRGENRYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKLGSVPIFYSPYLQLPVGDKRRSGFLIPNAKYSTKNGVEFSLPYYWNIAPNFDATITPHYMNKRGGVMWENEFRYLTQLGSGLTEFDYLPSDKVYEDDHSSDSNSRRWLFYWNHSGVIDQVWRLNADYTKVSDPDYFNDFSSKYGSSTDGYATQKFSAGYVNQNFDATVSTKQFQVFDRESSNSYSAEPQLDVNYYQNDVGPFDTHLYGQVAHFVNSNNNMPEATRVHFEPTINLPLSNGWGSLNTEAKLLATHYQQSNLDKYNAANGTDYKESVSRVMPQFKVDGKMVFERDLQEGFTQTLEPRVQYLYVPYRDQSEIGNYDSTLLQSDYTGLFRDRTYSGLDRIASANQVTTGLTSRVYDAAAVERFNISVGQIYYFTESRTGDDNINWENNDTTGSLVWAGDTYWRIADEWGLRGGIQYDTRLDNVATGNGTIEYRRDENRLVQLNYRYASPEYIQATLPSYSTAAQYKQGISQVGMTASWPIVDRWSVVGAYYYDTNTRKAANQMLGVQYNSCCYAIRLGYERKVNGWNSNDNGGESKYDNTFGINIELRGLSSNYGLGTQQMLRSNILPYQSSL
>NZ_CP011989.1|WP_002888329.1|4488494_4489781_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIVLQMGQKMGVKISDDQLDQAIANIAKQNNMTLDQMRSRLAYEGINYNTYRNQIRKEMLISEVRNNEVRRRITVLPQEVEALAKQIGDQNDASTELNLSHILIPLPENPTSDEVAAAQEQANSIVEQARNGANFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGGTQNISVTEVHARHILLKPSPIMNDAQAQAKLEQIAAEIKSGKITFAQAAKTYSEDPGSANQGGDLGWATPDIFDPAFRDALMRLNKGQTSGPVHSSFGWHLIELLDSRQVDRTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
>NZ_CP011989.1|WP_002888327.1|4489786_4490776_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MPETRKVVITPGEPAGIGPDLVVQLAQRDWPVELVICADGALLTDRAKRLGLPLSLLPYDPAQPPVPQRAGTLTLLNVPLNVPAEPGVLNVQNGAYVVETLARACDGCLSGEFAALVTGPVHKGNINDAGIAFTGHTEFFEERAKASKVVMMLATEELRVALVTTHLPLKAISEAITPELLREIITILDHDLRTKFGIAQPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLEEMRAKGMNLSGPLPADTLFQPKYLDHADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGQGKADVGSFITALNLAIKMIVNTQ
>NZ_CP011989.1|WP_002888324.1|4490772_4491594_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHSTMPYPVKEIRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGIDPAMRAENISVAQYCLMANWLSDNLPTKES
>NZ_CP011989.1|WP_002888323.1|4491596_4491974_+|Co2+/Mg2+-efflux-protein-ApaG
MIHSPRVCVQVQSVYIESQSSPEEERYVFAYTVTIRNLGRSQVQLLGRYWLITNGHGRETEVQGEGVVGEQPHIPAGGEYQYTSGAVIETPLGTMQGHYEMIDIDGAPFRIEIPVFRLAVPTLIH
>NZ_CP011989.1|WP_002888321.1|4491978_4492827_+|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)-ApaH
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>NZ_CP011989.1|WP_002888320.1|4493082_4493562_-|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_CP011989_1	1.1\|3998499\|36\|NZ_CP011989\|CRISPRCasFinder	3998499-3998534	36	MK448233	Klebsiella phage ST11-VIM1phi8.1, complete genome	8447-8482	1.0
NZ_CP011989_1	1.1\|3998499\|36\|NZ_CP011989\|CRISPRCasFinder	3998499-3998534	36	MK448235	Klebsiella phage ST512-KPC3phi13.1, complete genome	8447-8482	1.0
NZ_CP011989_1	1.1\|3998499\|36\|NZ_CP011989\|CRISPRCasFinder	3998499-3998534	36	MK448231	Klebsiella phage ST101-KPC2phi6.1, complete genome	11383-11418	1.0

1. spacer 1.1|3998499|36|NZ_CP011989|CRISPRCasFinder matches to MK448233 (Klebsiella phage ST11-VIM1phi8.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

2. spacer 1.1|3998499|36|NZ_CP011989|CRISPRCasFinder matches to MK448235 (Klebsiella phage ST512-KPC3phi13.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

3. spacer 1.1|3998499|36|NZ_CP011989|CRISPRCasFinder matches to MK448231 (Klebsiella phage ST101-KPC2phi6.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

446291 : 479546

uncultured_Caudovirales_phage(73.33%)

tail,tRNA,head,protease,terminase,portal,integrase,capsid

attL 463897:463914|attR 479891:479908

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002919147.1\|446291_447239_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	2.2e-07	37.2
WP_002919144.1\|447253_447763_-	peptide deformylase	E3SLL2	Synechococcus_phage	2.6e-18	40.3
WP_002919139.1\|447891_449016_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_002919137.1\|448987_449461_+	DUF494 domain-containing protein	NA	NA	NA	NA
WP_004145330.1\|449486_450029_+	topoisomerase DNA-binding C4 zinc finger domain-containing protein	NA	NA	NA	NA
WP_002919132.1\|450033_450606_+	L-threonylcarbamoyladenylate synthase type 1 TsaC	NA	NA	NA	NA
WP_002919126.1\|450609_451428_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_002919125.1\|451424_451682_+	DUF1488 domain-containing protein	NA	NA	NA	NA
WP_002919123.1\|451657_452212_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_002919103.1\|458005_458227_-	membrane protein	NA	NA	NA	NA
WP_002919102.1\|458520_461631_-	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_002919101.1\|461643_462783_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004150972.1\|463161_463812_+	acrEF/envCD operon transcriptional regulator	NA	NA	NA	NA
463897:463914	attL	NA	NA	NA	NA
WP_004150971.1\|464087_465314_+\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	1.8e-150	62.2
WP_004150970.1\|465406_466348_+	hypothetical protein	NA	NA	NA	NA
WP_001547839.1\|466529_466814_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_004150969.1\|466824_467604_+	phage antirepressor KilAC domain-containing protein	Q8HA02	Enterobacteria_phage	6.2e-40	51.5
WP_106918304.1\|468055_468325_+	host cell division inhibitor Icd-like protein	A0A2H4JGW3	uncultured_Caudovirales_phage	2.4e-44	94.4
WP_001549752.1\|468317_468506_+	hypothetical protein	NA	NA	NA	NA
WP_004150967.1\|468498_468813_+	hypothetical protein	NA	NA	NA	NA
WP_001549749.1\|469173_469539_+	hypothetical protein	NA	NA	NA	NA
WP_004150965.1\|469538_471674_+	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	3.4e-205	62.4
WP_004150964.1\|472016_472352_+	hypothetical protein	NA	NA	NA	NA
WP_004150963.1\|472400_472913_-	hypothetical protein	NA	NA	NA	NA
WP_001549743.1\|473176_474343_+\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	9.8e-207	95.9
WP_001547826.1\|474394_474955_+\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	1.2e-98	95.7
WP_004150962.1\|474956_476198_+\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	1.0e-230	96.5
WP_004150961.1\|476194_476530_+\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	3.7e-26	57.8
WP_001547824.1\|476526_476826_+\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JD08	uncultured_Caudovirales_phage	3.4e-39	80.8
WP_004150959.1\|476825_477269_+	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	2.8e-77	91.8
WP_004150957.1\|477261_477414_+	hypothetical protein	A0A2H4JCY9	uncultured_Caudovirales_phage	2.4e-17	88.0
WP_000113647.1\|477544_477901_+\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	5.5e-60	99.2
WP_004150955.1\|477884_479546_+\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	0.0e+00	98.0
479891:479908	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1685453 : 1692360

Planktothrix_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004175147.1\|1685453_1686317_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.7e-10	27.5
WP_002912638.1\|1686327_1687101_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-25	36.3
WP_004151134.1\|1687343_1688240_-	lipid kinase YegS	A0A1V0SBJ0	Catovirus	6.1e-15	29.8
WP_002912635.1\|1688482_1689844_-\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	2.5e-206	94.5
WP_002912634.1\|1690162_1690885_-	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	6.4e-31	33.2
WP_004151135.1\|1690881_1692360_-	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	1.1e-29	28.3

DBSCAN-SWA_3

1972703 : 2029188

Staphylococcus_phage(16.67%)

transposase,plate,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002910830.1\|1972703_1973450_+\|protease	proteasome-type protease	NA	NA	NA	NA
WP_002910809.1\|1973888_1974875_+	fatty acid desaturase	NA	NA	NA	NA
WP_004151439.1\|1974867_1975668_+	PhnD/SsuA/transferrin family substrate-binding protein	NA	NA	NA	NA
WP_002910767.1\|1975654_1975828_-	hypothetical protein	NA	NA	NA	NA
WP_004219597.1\|1976125_1976269_-	hypothetical protein	NA	NA	NA	NA
WP_002910764.1\|1976445_1977387_+	transcriptional regulator TdcA	NA	NA	NA	NA
WP_002910762.1\|1977480_1978470_+	bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA	NA	NA	NA
WP_004145486.1\|1978495_1979827_+	threonine/serine transporter TdcC	NA	NA	NA	NA
WP_002910759.1\|1979854_1981063_+	propionate kinase	NA	NA	NA	NA
WP_004152312.1\|1981091_1983386_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	2.3e-159	41.8
WP_004225356.1\|1983437_1983584_-	hypothetical protein	NA	NA	NA	NA
WP_002910729.1\|1983873_1984932_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002910727.1\|1985041_1985956_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_002910725.1\|1985965_1987243_+	high-affinity branched-chain amino acid ABC transporter permease LivM	NA	NA	NA	NA
WP_002910722.1\|1987239_1988115_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	9.5e-05	41.5
WP_002910721.1\|1988111_1988831_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.5e-11	26.0
WP_002910720.1\|1988836_1989730_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002910719.1\|1990013_1991657_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	9.8e-136	50.4
WP_002910717.1\|1991706_1992183_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002910715.1\|1992281_1993208_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004152313.1\|1993511_1994807_+	MFS transporter	Q6JIH2	Burkholderia_virus	1.3e-61	36.8
WP_004899032.1\|1994818_1995628_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_004152315.1\|1995602_1996502_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002910657.1\|1996611_1997094_-	cold shock domain-containing protein	NA	NA	NA	NA
WP_002910654.1\|1997284_1997983_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	2.6e-05	27.2
WP_002910652.1\|1998008_1998548_-	DUF2058 domain-containing protein	NA	NA	NA	NA
WP_002910650.1\|1998662_1998992_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_002910645.1\|1999560_2000901_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004152316.1\|2000897_2001551_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004152317.1\|2001554_2003252_+	OmpA family protein	NA	NA	NA	NA
WP_004152319.1\|2006215_2007571_+	S-type pyocin domain-containing protein	NA	NA	NA	NA
WP_002910593.1\|2007571_2008081_+	hypothetical protein	NA	NA	NA	NA
WP_002910591.1\|2008077_2008584_+	hypothetical protein	NA	NA	NA	NA
WP_002910589.1\|2008678_2008831_+	hypothetical protein	NA	NA	NA	NA
WP_002910586.1\|2008820_2009330_+	hypothetical protein	NA	NA	NA	NA
WP_022644641.1\|2010935_2011904_+\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	6.5e-180	96.3
WP_004199326.1\|2012045_2012228_+	hypothetical protein	NA	NA	NA	NA
WP_004153085.1\|2012224_2012554_+	hypothetical protein	NA	NA	NA	NA
WP_002910551.1\|2012550_2013057_+	hypothetical protein	NA	NA	NA	NA
WP_072093244.1\|2013516_2014548_+	hypothetical protein	NA	NA	NA	NA
WP_002910547.1\|2014571_2014877_+	hypothetical protein	NA	NA	NA	NA
WP_002910544.1\|2014898_2015792_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A7H6	Microcystis_virus	6.7e-14	30.5
WP_004217423.1\|2015837_2015954_+	hypothetical protein	NA	NA	NA	NA
WP_004152633.1\|2015975_2016869_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	1.7e-12	27.3
WP_038435084.1\|2016894_2017023_+	hypothetical protein	NA	NA	NA	NA
WP_002910539.1\|2017044_2017938_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	2.8e-12	27.1
WP_004152632.1\|2018113_2019004_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A7H6	Microcystis_virus	4.1e-11	29.8
WP_000019473.1\|2019340_2020321_+\|transposase	IS5-like element ISKpn26 family transposase	Q38213	Escherichia_phage	8.9e-185	99.1
WP_072093174.1\|2020940_2021126_+	hypothetical protein	NA	NA	NA	NA
WP_002910497.1\|2021423_2021690_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_004198077.1\|2021693_2022851_+	hypothetical protein	NA	NA	NA	NA
WP_004198071.1\|2022834_2026245_+	intracellular multiplication and macrophage-killing family protein	NA	NA	NA	NA
WP_002910495.1\|2026378_2028142_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004152910.1\|2028171_2029188_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_4

2692363 : 2703250

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004151613.1\|2692363_2695471_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6
WP_004151612.1\|2695525_2696791_+	MFS transporter	NA	NA	NA	NA
WP_001620097.1\|2696821_2697910_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
WP_002904006.1\|2697996_2698257_-	hypothetical protein	A0A077SK33	Escherichia_phage	3.5e-40	97.7
WP_004176269.1\|2698554_2699415_+	class A broad-spectrum beta-lactamase SHV-11	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_002210513.1\|2699435_2700197_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_004151610.1\|2700457_2701360_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	7.7e-159	99.3
WP_004151609.1\|2701371_2702637_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	6.6e-233	99.5
WP_002210516.1\|2702629_2703250_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0

DBSCAN-SWA_5

2897712 : 2970513

uncultured_Caudovirales_phage(35.29%)

holin,transposase,plate,terminase,integrase

attL 2961626:2961640|attR 2967635:2967649

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002902268.1\|2897712_2898798_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004151598.1\|2898761_2900516_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004151599.1\|2902187_2905613_-	type VI secretion protein VasK	NA	NA	NA	NA
WP_002902254.1\|2905596_2906736_-	hypothetical protein	NA	NA	NA	NA
WP_002902252.1\|2906732_2906990_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_004151601.1\|2907034_2909452_-	DUF2235 domain-containing protein	NA	NA	NA	NA
WP_002902178.1\|2910036_2910567_-	T6SS immunity phospholipase A1-binding lipoprotein Tli1-KP	NA	NA	NA	NA
WP_002902176.1\|2910635_2911166_-	T6SS immunity phospholipase A1-binding lipoprotein Tli1-KP	NA	NA	NA	NA
WP_002902174.1\|2911233_2911764_-	T6SS immunity phospholipase A1-binding lipoprotein Tli1-KP	NA	NA	NA	NA
WP_002902172.1\|2911832_2912363_-	T6SS immunity phospholipase A1-binding lipoprotein Tli1-KP	NA	NA	NA	NA
WP_002902169.1\|2912426_2913206_-	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_004228410.1\|2913206_2915576_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	9.1e-18	33.8
WP_002902163.1\|2915577_2918232_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	2.5e-96	33.4
WP_002902160.1\|2918496_2918988_-	type VI secretion system effector Hcp	NA	NA	NA	NA
WP_004151602.1\|2918992_2920699_-	OmpA family protein	NA	NA	NA	NA
WP_004151603.1\|2920695_2921385_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004218490.1\|2921381_2922725_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002902148.1\|2922734_2924279_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002902144.1\|2924321_2924813_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002902136.1\|2925658_2925907_+	DinI-like family protein	S5MQI1	Escherichia_phage	1.4e-25	70.4
WP_002902133.1\|2926129_2926414_-	hypothetical protein	NA	NA	NA	NA
WP_002902131.1\|2926518_2926728_-	hypothetical protein	NA	NA	NA	NA
WP_002902128.1\|2926724_2927456_-	hypothetical protein	NA	NA	NA	NA
WP_004218487.1\|2927466_2928195_-	hypothetical protein	NA	NA	NA	NA
WP_004152577.1\|2930545_2930743_-	hypothetical protein	NA	NA	NA	NA
WP_004152576.1\|2930742_2931609_-	hypothetical protein	A0A2H4IYR0	uncultured_Caudovirales_phage	1.9e-34	64.5
WP_004152575.1\|2931608_2932382_-	DUF2612 domain-containing protein	A0A2H4J1A9	uncultured_Caudovirales_phage	2.8e-77	54.4
WP_004152574.1\|2932378_2933575_-\|plate	baseplate J/gp47 family protein	A0A0M4RD32	Salmonella_phage	3.9e-158	72.9
WP_004152573.1\|2933574_2933928_-	hypothetical protein	A0A2H4J629	uncultured_Caudovirales_phage	2.3e-50	80.3
WP_004152572.1\|2933929_2934583_-	hypothetical protein	A0A2H4J8H6	uncultured_Caudovirales_phage	1.0e-59	63.5
WP_004152571.1\|2934636_2935203_-	hypothetical protein	NA	NA	NA	NA
WP_004199301.1\|2935245_2935428_-	hypothetical protein	NA	NA	NA	NA
WP_004152570.1\|2935477_2935819_-	hypothetical protein	A0A2H4J1A5	uncultured_Caudovirales_phage	1.8e-23	46.6
WP_004152569.1\|2935818_2936841_-	hypothetical protein	A0A2H4J1B2	uncultured_Caudovirales_phage	9.2e-100	54.2
WP_004217362.1\|2936843_2937071_-	hypothetical protein	A0A2H4J495	uncultured_Caudovirales_phage	4.6e-20	56.0
WP_004152567.1\|2937146_2937746_-	hypothetical protein	A0A2H4J1B3	uncultured_Caudovirales_phage	9.9e-54	57.6
WP_004152566.1\|2937745_2939749_-	lytic transglycosylase domain-containing protein	A0A2H4J9N7	uncultured_Caudovirales_phage	1.2e-247	63.6
WP_004152565.1\|2939738_2939891_-	hypothetical protein	A0A2H4J1A2	uncultured_Caudovirales_phage	7.6e-19	88.0
WP_004152564.1\|2939926_2940352_-	hypothetical protein	A0A2H4J2V6	uncultured_Caudovirales_phage	2.6e-40	63.4
WP_085955245.1\|2940678_2941870_+\|transposase	IS3-like element ISKpn18 family transposase	U5P429	Shigella_phage	3.5e-50	43.5
WP_004152178.1\|2941811_2942102_-	DUF3277 family protein	A0A2H4J619	uncultured_Caudovirales_phage	2.6e-23	85.5
WP_004152177.1\|2942112_2943258_-	DUF3383 domain-containing protein	A0A2H4J8G4	uncultured_Caudovirales_phage	6.3e-166	76.9
WP_004152176.1\|2943261_2943702_-	hypothetical protein	A0A2H4J1A0	uncultured_Caudovirales_phage	1.6e-40	51.7
WP_001116156.1\|2943796_2944183_-	hypothetical protein	A0A2H4J1A4	uncultured_Caudovirales_phage	1.1e-48	78.2
WP_000834982.1\|2944182_2944689_-	hypothetical protein	NA	NA	NA	NA
WP_000113538.1\|2944685_2945105_-	DUF4054 domain-containing protein	A0A0M5M3S2	Salmonella_phage	3.3e-40	60.7
WP_000725700.1\|2945073_2945355_-	hypothetical protein	NA	NA	NA	NA
WP_001132269.1\|2945394_2946336_-	DUF2184 domain-containing protein	A0A2H4J191	uncultured_Caudovirales_phage	1.7e-137	77.1
WP_000528476.1\|2946347_2946842_-	hypothetical protein	A0A2H4JHM9	uncultured_Caudovirales_phage	4.2e-50	62.7
WP_004199270.1\|2946845_2948048_-	DUF2213 domain-containing protein	A0A0M4R5A6	Salmonella_phage	2.6e-106	54.1
WP_004152174.1\|2948099_2948648_-	hypothetical protein	A0A0M4REK0	Salmonella_phage	3.0e-49	56.3
WP_004152173.1\|2948703_2950155_-	DUF1073 domain-containing protein	A0A0M4S6U1	Salmonella_phage	3.8e-192	68.8
WP_004152172.1\|2950392_2951793_-\|terminase	PBSX family phage terminase large subunit	A0A077KAW0	Edwardsiella_phage	9.4e-188	69.0
WP_004218030.1\|2951743_2952232_-	hypothetical protein	NA	NA	NA	NA
WP_004152170.1\|2952597_2952918_-	hypothetical protein	NA	NA	NA	NA
WP_004153952.1\|2953152_2953542_-	lipase chaperone	A0A192Y6H8	Salmonella_phage	9.4e-21	49.2
WP_004152169.1\|2953538_2954069_-	lysozyme	K7PLY1	Enterobacteria_phage	2.7e-79	77.1
WP_004146526.1\|2954071_2954320_-\|holin	class II holin family protein	NA	NA	NA	NA
WP_004152167.1\|2954725_2955508_-	antitermination protein	F1C595	Cronobacter_phage	7.2e-113	76.8
WP_004198239.1\|2955504_2955981_-	hypothetical protein	A0A286N2Q1	Klebsiella_phage	1.8e-90	100.0
WP_004198233.1\|2955977_2956940_-	toprim domain-containing protein	A0A286N2Q0	Klebsiella_phage	4.8e-183	99.4
WP_004198228.1\|2956941_2958600_-	DEAD/DEAH box helicase	A0A286N2P9	Klebsiella_phage	0.0e+00	96.0
WP_004152162.1\|2959175_2959397_-	helix-turn-helix transcriptional regulator	A0A286S2C1	Klebsiella_phage	3.0e-32	100.0
WP_004152161.1\|2959494_2960163_+	LexA family transcriptional regulator	A0A286S2B2	Klebsiella_phage	2.4e-125	99.5
WP_004152160.1\|2960333_2960648_+	hypothetical protein	A0A286S1T9	Klebsiella_phage	1.0e-49	100.0
WP_004152159.1\|2960640_2960829_+	hypothetical protein	A0A286S1P8	Klebsiella_phage	4.6e-26	100.0
WP_004152158.1\|2960998_2961364_+	hypothetical protein	A0A286S1Q6	Klebsiella_phage	6.9e-58	99.2
WP_004152157.1\|2961356_2961611_+	hypothetical protein	A0A286SGR4	Klebsiella_phage	3.1e-41	97.6
WP_004177208.1\|2961582_2961801_+	hypothetical protein	A0A286S1P6	Klebsiella_phage	6.6e-32	98.6
2961626:2961640	attL	NA	NA	NA	NA
WP_004152156.1\|2961797_2962223_+	hypothetical protein	A0A286S1S2	Klebsiella_phage	3.5e-53	77.9
WP_004152155.1\|2962219_2962414_+	hypothetical protein	NA	NA	NA	NA
WP_004152154.1\|2962410_2963238_+	hypothetical protein	Q8W654	Enterobacteria_phage	5.5e-111	84.0
WP_004152153.1\|2963342_2963861_+	hypothetical protein	A0A286S1S7	Klebsiella_phage	1.7e-94	98.8
WP_004154298.1\|2963866_2964577_+	Rha family transcriptional regulator	A0A286S260	Klebsiella_phage	2.1e-111	88.3
WP_004152151.1\|2964566_2964791_+	hypothetical protein	A0A286S2B3	Klebsiella_phage	3.1e-29	89.2
WP_004152150.1\|2964787_2965000_+	hypothetical protein	A0A286S2B6	Klebsiella_phage	3.4e-33	98.6
WP_014343018.1\|2965242_2965476_+	hypothetical protein	NA	NA	NA	NA
WP_004198245.1\|2965548_2965695_+	hypothetical protein	A0A1B5FPC2	Escherichia_phage	2.9e-15	70.8
WP_004152148.1\|2965654_2965897_+	hypothetical protein	A0A0M4RTZ2	Salmonella_phage	2.2e-20	73.8
WP_004152147.1\|2965877_2967059_-\|integrase	site-specific integrase	A0A0M4QX09	Salmonella_phage	5.6e-202	84.2
WP_016197745.1\|2967255_2967804_+	DJ-1/PfpI family protein	NA	NA	NA	NA
2967635:2967649	attR	NA	NA	NA	NA
WP_004152145.1\|2968002_2969535_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	1.1e-21	30.0
WP_004152144.1\|2969751_2970513_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.4e-20	32.5

DBSCAN-SWA_6

3294884 : 3309937

Enterobacteria_phage(33.33%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004199491.1\|3294884_3295160_+	hypothetical protein	A0A0M3ULK3	Salmonella_phage	1.9e-23	60.9
WP_004199521.1\|3295133_3295703_-	recombinase family protein	A0A286S1P7	Klebsiella_phage	3.9e-84	86.8
WP_016197598.1\|3295793_3297305_+	hypothetical protein	H6X4Y6	Enterobacteria_phage	9.8e-58	33.7
WP_004199475.1\|3297315_3297510_+	hypothetical protein	NA	NA	NA	NA
WP_020803012.1\|3297708_3300144_-	hypothetical protein	A0A0A8J9V7	Klebsiella_phage	5.2e-69	35.2
WP_004199504.1\|3300235_3300388_-	DUF1378 family protein	NA	NA	NA	NA
WP_004199533.1\|3300384_3300915_-	hypothetical protein	K7P6W1	Enterobacteria_phage	3.7e-36	48.9
WP_004199518.1\|3300911_3301451_-	lysozyme	H6WRZ4	Salmonella_phage	4.5e-82	78.7
WP_004199490.1\|3301452_3301668_-\|holin	class II holin family protein	A5LH82	Enterobacteria_phage	1.1e-12	61.0
WP_123600138.1\|3302175_3302580_-	hypothetical protein	NA	NA	NA	NA
WP_004199484.1\|3302608_3305533_-	hypothetical protein	W6MWW8	Pseudomonas_phage	1.8e-196	41.3
WP_016197574.1\|3305532_3306915_-	hypothetical protein	NA	NA	NA	NA
WP_004199529.1\|3307222_3309937_-	lytic transglycosylase domain-containing protein	K4NWI2	Pseudomonas_phage	2.2e-31	26.8

DBSCAN-SWA_7

3314496 : 3340262

Pectobacterium_phage(28.0%)

tail,protease,head,integrase

attL 3324196:3324210|attR 3340747:3340761

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191050.1\|3314496_3314970_-	hypothetical protein	K4NYY6	Pseudomonas_phage	1.8e-26	46.3
WP_004199478.1\|3315008_3316004_-	bbp17	W6MW28	Pseudomonas_phage	2.1e-104	60.2
WP_004199538.1\|3316014_3316752_-	hypothetical protein	NA	NA	NA	NA
WP_004199528.1\|3316738_3317062_-	hypothetical protein	NA	NA	NA	NA
WP_004141558.1\|3317064_3318729_-\|head,tail	head-tail connector protein	A0A221SAN2	Ralstonia_phage	3.1e-105	39.4
WP_004199513.1\|3318728_3320123_-	hypothetical protein	A0A0E3JIA1	Rhodoferax_phage	2.4e-58	36.4
WP_004199526.1\|3320207_3320660_-	DNA-packaging protein	A3EYX3	Salmonella_phage	1.1e-49	66.4
WP_004199477.1\|3320666_3320927_-	hypothetical protein	NA	NA	NA	NA
WP_004199520.1\|3320910_3321144_-	hypothetical protein	NA	NA	NA	NA
WP_004199492.1\|3321205_3321730_-	DUF2829 domain-containing protein	A0A1B0VMG3	Pseudomonas_phage	2.5e-45	54.1
WP_004199525.1\|3321770_3322211_-	phage family protein	R9TRJ4	Aeromonas_phage	4.3e-14	43.8
WP_004199527.1\|3322216_3322564_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_071570746.1\|3322551_3322875_-	DUF968 domain-containing protein	A0A1I9KFA7	Aeromonas_phage	6.8e-25	55.8
WP_004199500.1\|3322864_3323458_-	DUF1367 family protein	H9C173	Pectobacterium_phage	7.2e-81	72.1
WP_025712904.1\|3323526_3323718_-	hypothetical protein	NA	NA	NA	NA
WP_004199485.1\|3323898_3324237_-	hypothetical protein	A0A193GYX4	Enterobacter_phage	1.5e-46	81.1
3324196:3324210	attL	NA	NA	NA	NA
WP_004199511.1\|3324229_3324433_-	hypothetical protein	NA	NA	NA	NA
WP_004199524.1\|3324432_3324648_-	hypothetical protein	K7PKY3	Enterobacterial_phage	1.8e-21	65.7
WP_004199508.1\|3324640_3325585_-	DUF551 domain-containing protein	R9TQX3	Aeromonas_phage	2.1e-37	68.0
WP_004199474.1\|3325581_3325971_-	hypothetical protein	R9TME7	Aeromonas_phage	8.8e-11	36.8
WP_004199493.1\|3326098_3326884_-	hypothetical protein	C7BGF1	Burkholderia_phage	4.8e-64	52.9
WP_004191074.1\|3326923_3327157_-	hypothetical protein	NA	NA	NA	NA
WP_016197575.1\|3327160_3327811_-	hypothetical protein	NA	NA	NA	NA
WP_004199519.1\|3327849_3329238_-	AAA family ATPase	Q8HA30	Enterobacteria_phage	1.5e-105	47.3
WP_004199531.1\|3329234_3330218_-	helix-turn-helix domain-containing protein	H9C164	Pectobacterium_phage	1.3e-39	73.8
WP_016197573.1\|3330220_3330379_-	hypothetical protein	NA	NA	NA	NA
WP_004199487.1\|3330462_3330909_-	hypothetical protein	H9C162	Pectobacterium_phage	7.4e-30	56.1
WP_029499131.1\|3330969_3331203_-	helix-turn-helix transcriptional regulator	A0A0U2S629	Escherichia_phage	5.8e-10	44.4
WP_004199482.1\|3331309_3331765_+	helix-turn-helix domain-containing protein	A0A0U2QW76	Escherichia_phage	6.2e-32	50.0
WP_020313637.1\|3332775_3333009_+	hypothetical protein	NA	NA	NA	NA
WP_004199499.1\|3333053_3335186_+	hypothetical protein	H9C157	Pectobacterium_phage	1.7e-95	34.6
WP_004199473.1\|3335185_3335752_+	siphovirus Gp157 family protein	H9C156	Pectobacterium_phage	2.5e-51	61.5
WP_004141609.1\|3335753_3335939_+	hypothetical protein	H9C155	Pectobacterium_phage	8.1e-07	44.3
WP_004199480.1\|3336148_3336373_+	DUF4224 domain-containing protein	H9C153	Pectobacterium_phage	4.5e-20	68.1
WP_016197576.1\|3336376_3337405_+\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	4.4e-94	54.1
WP_004150834.1\|3337680_3339333_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002898458.1\|3339602_3340262_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	3.2e-37	46.6
3340747:3340761	attR	NA	NA	NA	NA

DBSCAN-SWA_8

3425054 : 3519207

Salmonella_phage(57.63%)

tail,transposase,tRNA,head,lysis,plate,protease,terminase,portal,integrase,capsid

attL 3480582:3480600|attR 3519282:3519300

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002898139.1\|3425054_3426347_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	7.3e-94	44.7
WP_002898137.1\|3426437_3427781_-	replication-associated recombination protein RarA	G3MBE0	Bacillus_virus	7.3e-81	40.8
WP_002898132.1\|3427789_3428401_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_004150846.1\|3428523_3432777_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	5.2e-88	49.2
WP_000228469.1\|3432912_3433407_-	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_002898019.1\|3433939_3434908_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	3.2e-62	44.0
WP_002898017.1\|3435022_3436789_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	2.3e-21	25.9
WP_004150847.1\|3436789_3438511_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3
WP_002898014.1\|3438555_3439257_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|3439610_3439829_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_002896522.1\|3439949_3442229_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
WP_002896520.1\|3442259_3442577_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896516.1\|3442902_3443124_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_004150848.1\|3443200_3445141_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.9e-37	40.5
WP_002896440.1\|3445137_3446253_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7
WP_002896437.1\|3446399_3448058_-	ATP-dependent endonuclease	NA	NA	NA	NA
WP_002896434.1\|3448477_3449173_+	aquaporin Z	NA	NA	NA	NA
WP_004147773.1\|3449288_3450188_+	lysine exporter LysO family protein	NA	NA	NA	NA
WP_002896412.1\|3450331_3451984_+	hydroxylamine reductase	NA	NA	NA	NA
WP_002896410.1\|3451994_3452963_+	NADH oxidoreductase	NA	NA	NA	NA
WP_002896408.1\|3453174_3453609_-	DoxX family protein	NA	NA	NA	NA
WP_002896406.1\|3453760_3455479_+	ubiquinone-dependent pyruvate dehydrogenase	NA	NA	NA	NA
WP_002896404.1\|3455517_3456519_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_002896401.1\|3456529_3457972_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002896399.1\|3458059_3459073_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_002896397.1\|3459069_3459900_-	N-acetylmuramoyl-L-alanine amidase	A0A1B0UZW5	Roseobacter_phage	4.1e-05	31.6
WP_004150851.1\|3459931_3461071_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_002896394.1\|3461948_3462464_+	lipoprotein	NA	NA	NA	NA
WP_002896392.1\|3462690_3463419_+	arginine ABC transporter ATP-binding protein ArtP	G9BWD6	Planktothrix_phage	1.2e-29	37.1
WP_002896390.1\|3463439_3464171_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002896386.1\|3464177_3464894_+	arginine ABC transporter permease ArtQ	NA	NA	NA	NA
WP_004150852.1\|3464893_3465562_+	arginine ABC transporter permease ArtM	NA	NA	NA	NA
WP_002896384.1\|3465745_3466477_+	ABC transporter substrate-binding protein ArtJ	NA	NA	NA	NA
WP_002896382.1\|3466519_3467992_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	7.9e-28	31.8
WP_002896380.1\|3467988_3468705_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.1e-34	36.9
WP_002896378.1\|3468783_3469911_-	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	A0A2K5B251	Erysipelothrix_phage	1.3e-19	25.6
WP_002896372.1\|3470500_3471346_-	putrescine ABC transporter permease PotI	NA	NA	NA	NA
WP_002896371.1\|3471342_3472296_-	putrescine ABC transporter permease PotH	NA	NA	NA	NA
WP_002896370.1\|3472306_3473440_-	putrescine ABC transporter ATP-binding subunit PotG	G3M9Y6	Bacillus_virus	2.2e-30	34.9
WP_002896368.1\|3473603_3474716_-	spermidine/putrescine ABC transporter substrate-binding protein PotF	NA	NA	NA	NA
WP_002896365.1\|3475064_3475544_-	YbjN domain-containing protein	NA	NA	NA	NA
WP_002896363.1\|3475632_3476535_-	30S ribosomal protein S6--L-glutamate ligase	A0A1D7SR78	Cyanophage	2.0e-34	35.3
WP_002896354.1\|3477356_3477644_-	YbjC family protein	NA	NA	NA	NA
WP_002896352.1\|3477846_3478110_+	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	1.6e-27	73.1
WP_002896351.1\|3478116_3478500_-	inner membrane protein YbjM	NA	NA	NA	NA
WP_004179131.1\|3478766_3480452_+	aspartate:alanine antiporter	NA	NA	NA	NA
3480582:3480600	attL	NA	NA	NA	NA
WP_000972391.1\|3480671_3480890_-	ogr/Delta-like zinc finger family protein	Q53ZE7	Salmonella_virus	7.5e-20	69.0
WP_002896225.1\|3480981_3482082_-	phage late control D family protein	A0A1S6KZZ5	Salmonella_phage	4.9e-176	87.4
WP_002896224.1\|3482078_3482564_-\|tail	phage tail protein	E5G6Q2	Salmonella_phage	7.2e-63	75.6
WP_002896222.1\|3482560_3485188_-\|tail	phage tail tape measure protein	E5FFG5	Burkholderia_phage	5.6e-117	42.0
WP_002896220.1\|3485180_3485300_-\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.2e-13	87.2
WP_002896204.1\|3485314_3485614_-\|tail	phage tail assembly protein	E5G6P9	Salmonella_phage	3.7e-33	79.0
WP_002896201.1\|3485666_3486182_-\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	1.3e-81	85.4
WP_002896193.1\|3486191_3487364_-\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	1.9e-210	93.3
WP_002896191.1\|3487502_3488579_-\|tail	phage tail protein	Q37842	Escherichia_phage	1.2e-25	44.8
WP_002896188.1\|3488608_3488812_-	hypothetical protein	NA	NA	NA	NA
WP_002896186.1\|3488808_3489540_-	hypothetical protein	NA	NA	NA	NA
WP_019724930.1\|3489543_3490278_-	hypothetical protein	NA	NA	NA	NA
WP_004150856.1\|3492496_3493096_-\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	1.3e-58	60.5
WP_002896182.1\|3493088_3493997_-\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	7.6e-106	66.9
WP_002896179.1\|3493983_3494346_-	GPW/gp25 family protein	A0A1S6KZZ4	Salmonella_phage	5.8e-49	84.7
WP_002896177.1\|3494342_3494915_-\|plate	phage baseplate assembly protein V	E5G6N6	Salmonella_phage	4.7e-77	72.3
WP_004150857.1\|3495009_3495702_+	hypothetical protein	NA	NA	NA	NA
WP_002896175.1\|3495698_3496145_-	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	2.2e-50	71.2
WP_002896172.1\|3496137_3496569_-\|tail	phage tail protein	A0A1S6KZY0	Salmonella_phage	9.9e-64	82.5
WP_002896170.1\|3496531_3496678_-	hypothetical protein	A0A1S6KZX6	Salmonella_phage	6.0e-13	76.1
WP_002896168.1\|3496664_3497093_-\|lysis	LysB family phage lysis regulatory protein	A0A1S6KZX8	Salmonella_phage	9.6e-51	77.9
WP_002896163.1\|3497089_3497473_-	hypothetical protein	A0A1S6KZZ2	Salmonella_phage	2.1e-17	42.0
WP_002896161.1\|3497477_3497987_-	lysozyme	E5G6N1	Salmonella_phage	2.1e-81	83.4
WP_002896158.1\|3497967_3498183_-	hypothetical protein	E5G6N0	Salmonella_phage	3.6e-30	90.1
WP_002896155.1\|3498186_3498390_-\|tail	tail protein X	A0A1S6KZY4	Salmonella_phage	1.3e-29	88.1
WP_002896151.1\|3498389_3498854_-\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	8.4e-77	89.0
WP_000059191.1\|3498949_3499600_-\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	8.7e-112	96.3
WP_002895972.1\|3499603_3500662_-\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	1.1e-180	93.1
WP_002895967.1\|3500678_3501512_-\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	6.3e-123	88.8
WP_004150858.1\|3501654_3503421_+\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.0
WP_002895959.1\|3503420_3504446_+\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	7.6e-171	86.7
WP_000019473.1\|3504654_3505635_-\|transposase	IS5-like element ISKpn26 family transposase	Q38213	Escherichia_phage	8.9e-185	99.1
WP_004199124.1\|3505707_3507450_-	AIPR family protein	NA	NA	NA	NA
WP_000700647.1\|3507725_3508403_-	hypothetical protein	NA	NA	NA	NA
WP_001217575.1\|3508517_3508751_-	DinI family protein	E5G6M1	Salmonella_phage	4.7e-36	100.0
WP_001154434.1\|3508761_3508950_-	hypothetical protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
WP_004150862.1\|3509103_3511518_-	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	97.5
WP_004150863.1\|3511514_3512372_-	DNA adenine methylase	E5G6L8	Salmonella_phage	2.0e-156	95.4
WP_000752622.1\|3512368_3512596_-	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	6.0e-36	98.7
WP_004150864.1\|3512595_3512829_-	DUF2732 family protein	E5G6L6	Salmonella_phage	4.1e-32	96.1
WP_000963473.1\|3512896_3513238_-	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	4.6e-56	99.1
WP_000956179.1\|3513201_3513402_-	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	1.6e-32	97.0
WP_000460893.1\|3513409_3513919_-	phage regulatory CII family protein	E5G6L3	Salmonella_phage	5.8e-87	98.8
WP_000188448.1\|3513951_3514173_-	hypothetical protein	NA	NA	NA	NA
WP_004152885.1\|3514318_3515197_+	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	1.7e-30	39.9
WP_004150866.1\|3515208_3516153_+	hypothetical protein	NA	NA	NA	NA
WP_004178082.1\|3516251_3517739_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_014342959.1\|3518226_3519207_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	1.4e-97	57.2
3519282:3519300	attR	NA	NA	NA	NA

DBSCAN-SWA_9

3964314 : 4009589

Cronobacter_phage(25.0%)

holin,tRNA,head,lysis

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004151249.1\|3964314_3966792_-	MoaD/ThiS family protein	F1C5A7	Cronobacter_phage	2.7e-198	45.6
WP_004151250.1\|3966778_3967174_-	C40 family peptidase	F1C5F2	Cronobacter_phage	8.0e-36	54.0
WP_004199076.1\|3967170_3967641_-	hypothetical protein	R9TPR6	Aeromonas_phage	2.5e-28	41.0
WP_004151252.1\|3967640_3968117_-	hypothetical protein	A0A2P1MXB5	Escherichia_phage	3.0e-37	49.7
WP_004151253.1\|3968159_3971606_-	tape measure protein	Q5G8W8	Enterobacteria_phage	1.4e-163	48.6
WP_004151254.1\|3971698_3972202_-	hypothetical protein	NA	NA	NA	NA
WP_004151255.1\|3972329_3973115_-	phage repressor protein	A0A2L1IV39	Escherichia_phage	1.9e-84	59.7
WP_004151256.1\|3973180_3973894_-	hypothetical protein	H6WRU8	Salmonella_phage	3.9e-49	50.2
WP_004151257.1\|3973883_3974054_-	Arc family DNA-binding protein	I6R9A8	Salmonella_phage	6.1e-17	87.0
WP_004151258.1\|3974153_3974513_+	Arc family DNA-binding protein	A0A0P0ZBD1	Stx2-converting_phage	3.8e-16	47.5
WP_004151259.1\|3974529_3975000_-	hypothetical protein	NA	NA	NA	NA
WP_004151260.1\|3975293_3975548_-	hypothetical protein	K7PM89	Enterobacteria_phage	6.7e-20	73.0
WP_004151261.1\|3975550_3976306_-	KilA-N domain-containing protein	K7PGT4	Enterobacteria_phage	2.4e-60	51.0
WP_004151262.1\|3976481_3977159_-	hypothetical protein	F1C5E8	Cronobacter_phage	4.8e-73	57.9
WP_004151263.1\|3977211_3977964_-	Ig domain-containing protein	G0ZNE6	Cronobacter_phage	5.8e-43	42.1
WP_004151264.1\|3978032_3978425_-	hypothetical protein	G0ZNE4	Cronobacter_phage	5.1e-35	52.7
WP_004151265.1\|3978421_3978847_-	hypothetical protein	R9TPP7	Aeromonas_phage	5.1e-28	47.9
WP_004151266.1\|3978849_3979212_-	hypothetical protein	A0A173GCE0	Salmonella_phage	1.8e-18	45.0
WP_004151267.1\|3979211_3979385_-	hypothetical protein	I6R0P9	Salmonella_phage	1.4e-13	56.1
WP_004151268.1\|3979384_3979765_-	hypothetical protein	F1C5E2	Cronobacter_phage	5.3e-29	55.3
WP_004151269.1\|3979767_3980007_-	hypothetical protein	NA	NA	NA	NA
WP_004151270.1\|3980017_3981112_-	hypothetical protein	F1C5E1	Cronobacter_phage	1.7e-123	62.8
WP_004151271.1\|3981123_3981552_-	hypothetical protein	F1C5E0	Cronobacter_phage	1.6e-42	60.8
WP_004151272.1\|3981555_3982941_-	DUF2213 domain-containing protein	F1C5D9	Cronobacter_phage	2.3e-154	60.0
WP_004151273.1\|3983013_3983490_-	hypothetical protein	NA	NA	NA	NA
WP_004151274.1\|3983531_3984536_-\|head	phage head morphogenesis protein	F1C5D8	Cronobacter_phage	9.0e-116	69.7
WP_004151275.1\|3984510_3985932_-	DUF1073 domain-containing protein	F1C5D7	Cronobacter_phage	9.6e-148	57.1
WP_004151276.1\|3985944_3987417_-	hypothetical protein	A0A1W6JNY3	Morganella_phage	1.3e-248	82.5
WP_004151277.1\|3987416_3988019_-	hypothetical protein	G8C7P2	Escherichia_phage	5.4e-76	80.9
WP_004151279.1\|3988389_3988719_+	hypothetical protein	NA	NA	NA	NA
WP_004151280.1\|3988824_3989289_-\|lysis	lysis protein	Q76H63	Enterobacteria_phage	2.4e-55	73.2
WP_004151281.1\|3989285_3989816_-	lysozyme	G9L6J6	Escherichia_phage	6.0e-79	78.5
WP_004151282.1\|3989818_3990067_-\|holin	class II holin family protein	NA	NA	NA	NA
WP_004151283.1\|3990976_3991666_-	antitermination protein	I6PDF8	Cronobacter_phage	1.4e-56	54.5
WP_004151284.1\|3991662_3992193_-	HNH endonuclease	A0A193GYW9	Enterobacter_phage	5.2e-30	43.1
WP_004151285.1\|3992185_3992323_-	YlcG family protein	NA	NA	NA	NA
WP_004151286.1\|3992319_3992955_-	recombination protein NinG	M9NYX8	Enterobacteria_phage	2.7e-81	77.9
WP_004151287.1\|3992947_3993118_-	NinE family protein	G8C7V4	Escherichia_phage	1.3e-14	73.2
WP_004151288.1\|3993117_3993573_-	YbcN family protein	K7P7B8	Enterobacteria_phage	8.0e-56	69.5
WP_004151291.1\|3994073_3994721_-	DUF551 domain-containing protein	A5LH60	Enterobacteria_phage	4.5e-12	32.6
WP_004151292.1\|3994717_3994894_-	hypothetical protein	NA	NA	NA	NA
WP_004151293.1\|3994893_3995736_-	ead/Ea22-like family protein	A0A2H4FRZ0	Salmonella_phage	1.8e-29	60.8
WP_004151294.1\|3995842_3996349_-	hypothetical protein	A0A0A6Z565	Enterobacter_phage	3.0e-27	59.6
WP_004151295.1\|3996345_3996639_-	protein ren	O48423	Enterobacteria_phage	3.3e-26	65.6
WP_004230547.1\|3996638_3998054_-	AAA family ATPase	Q9MCT4	Escherichia_phage	1.8e-183	67.1
WP_004230546.1\|3998058_3998910_-	hypothetical protein	F1C5C3	Cronobacter_phage	5.3e-85	56.3
WP_004151298.1\|3998950_3999097_-	hypothetical protein	NA	NA	NA	NA
WP_001548453.1\|3999182_3999404_-	hypothetical protein	G8EYH8	Enterobacteria_phage	6.9e-05	41.7
WP_004151299.1\|3999444_3999678_-	helix-turn-helix domain-containing protein	G8C7U2	Escherichia_phage	4.3e-13	50.7
WP_004151300.1\|3999805_4000495_+	helix-turn-helix transcriptional regulator	G8C7U1	Escherichia_phage	4.3e-61	52.2
WP_004151301.1\|4000845_4001061_+	hypothetical protein	B5WZV1	Pseudomonas_phage	1.6e-09	48.6
WP_004151302.1\|4001057_4001168_+	hypothetical protein	NA	NA	NA	NA
WP_004151303.1\|4001160_4001355_+	hypothetical protein	NA	NA	NA	NA
WP_004151304.1\|4001443_4001728_+	host nuclease inhibitor GamL	G8C7T1	Escherichia_phage	8.0e-30	62.8
WP_004151305.1\|4001743_4002589_+	phage recombination protein Bet	A0A1I9KF88	Aeromonas_phage	6.9e-69	59.2
WP_004151306.1\|4002585_4003266_+	YqaJ viral recombinase family protein	A0A0M3ULE0	Salmonella_phage	7.9e-124	93.4
WP_004151308.1\|4003262_4003421_+	DUF1317 family protein	A0A0N7CHV0	Escherichia_phage	3.0e-10	60.8
WP_004151310.1\|4003417_4004074_+	DNA methyltransferase	G8C7S6	Escherichia_phage	2.7e-113	87.5
WP_004151312.1\|4004070_4004838_+	hypothetical protein	D5LH17	Escherichia_phage	1.7e-66	53.4
WP_004151314.1\|4004834_4005053_+	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	1.2e-09	47.2
WP_004151316.1\|4005054_4005270_+	TraR/DksA family transcriptional regulator	A0A0K2FI84	Escherichia_phage	4.0e-13	52.9
WP_004151317.1\|4005271_4005607_+	excisionase family DNA-binding protein	NA	NA	NA	NA
WP_004143017.1\|4007077_4007944_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.3e-30	34.8
WP_004143016.1\|4007945_4008158_+	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_004143010.1\|4008203_4009589_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.5e-46	35.4

DBSCAN-SWA_10

4219142 : 4230796

Enterobacteria_phage(70.0%)

integrase

attL 4219592:4219606|attR 4242649:4242663

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004144574.1\|4219142_4220246_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.8e-62	40.5
4219592:4219606	attL	NA	NA	NA	NA
WP_002889940.1\|4220256_4221510_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	8.9e-89	44.9
WP_002889938.1\|4221862_4223053_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	6.4e-145	62.7
WP_004152029.1\|4223040_4223991_+	AAA family ATPase	A0A1X9IGI7	Lactococcus_phage	1.2e-13	27.1
WP_004152979.1\|4223990_4224416_+	hypothetical protein	NA	NA	NA	NA
WP_002889930.1\|4224984_4225551_-	phage polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.5e-59	64.3
WP_002889919.1\|4225568_4225814_-	ogr/Delta-like zinc finger family protein	Q7M294	Enterobacteria_phage	1.9e-19	58.0
WP_002889917.1\|4225810_4226548_-	hypothetical protein	Q7M2A2	Enterobacteria_phage	9.0e-73	60.7
WP_002889915.1\|4227089_4227356_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	2.6e-30	71.6
WP_024940872.1\|4227352_4227910_+	ash family protein	Q7M2A7	Enterobacteria_phage	1.8e-33	70.4
WP_002889911.1\|4227906_4228134_+	hypothetical protein	NA	NA	NA	NA
WP_002889897.1\|4228130_4228451_+	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_002889890.1\|4228462_4230796_+	toprim domain-containing protein	Q7M2A8	Enterobacteria_phage	0.0e+00	82.2
4242649:4242663	attR	NA	NA	NA	NA

DBSCAN-SWA_11

4699037 : 4704862

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152207.1\|4699037_4701371_-	toprim domain-containing protein	Q7M2A8	Enterobacteria_phage	0.0e+00	83.9
WP_004152206.1\|4701385_4701706_-	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_004152205.1\|4701702_4701930_-	hypothetical protein	NA	NA	NA	NA
WP_004153681.1\|4701926_4702475_-	host cell division inhibitor Icd-like protein	Q7M2A7	Enterobacteria_phage	1.1e-30	69.4
WP_000556592.1\|4702471_4702738_-	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	2.0e-30	71.6
WP_004152204.1\|4703298_4704036_+	hypothetical protein	Q7M2A2	Enterobacteria_phage	1.1e-70	59.4
WP_004152203.1\|4704032_4704278_+	ogr/Delta-like zinc finger family protein	Q7M294	Enterobacteria_phage	5.5e-19	56.8
WP_004152202.1\|4704295_4704862_+	phage polarity suppression protein	Q7M2A1	Enterobacteria_phage	9.7e-59	63.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP011990

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 3336

Shigella_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152718.1\|150_363_+	hypothetical protein	NA	NA	NA	NA
WP_004152719.1\|373_598_+	hypothetical protein	NA	NA	NA	NA
WP_004152720.1\|678_999_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	6.8e-09	39.5
WP_004152721.1\|988_1267_+	helix-turn-helix transcriptional regulator	O64356	Escherichia_phage	2.5e-07	39.4
WP_004152722.1\|1267_1681_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004178064.1\|2514_3336_+	DUF945 domain-containing protein	K4F5L3	Cronobacter_phage	2.6e-44	40.4

DBSCAN-SWA_2

37489 : 38215

Xanthomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152303.1\|37489_38215_+	type-F conjugative transfer system pilin acetylase TraX	A0A1D6ZIU7	Xanthomonas_phage	5.5e-06	29.4

DBSCAN-SWA_3

42774 : 102062

Stx2-converting_phage(16.67%)

bacteriocin,transposase,integrase

attL 45494:45510|attR 104512:104528

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152296.1\|42774_43053_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_009485932.1\|43393_43873_+	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	9.8e-20	35.2
WP_004199332.1\|44193_44472_+	replication regulatory protein RepA	NA	NA	NA	NA
WP_004171457.1\|44688_44766_+	RepA leader peptide Tap	NA	NA	NA	NA
WP_004152292.1\|44758_45616_+	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
45494:45510	attL	NA	NA	NA	NA
WP_000093087.1\|47062_49258_-	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_004152291.1\|49254_50571_-	ATP-binding protein	NA	NA	NA	NA
WP_004152290.1\|50574_52884_-	TerB N-terminal domain-containing protein	NA	NA	NA	NA
WP_003846917.1\|54589_55843_-	lactose permease	NA	NA	NA	NA
WP_004152287.1\|55894_58969_-	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	96.7
WP_004152286.1\|59090_60173_-	DNA-binding transcriptional repressor LacI	C6ZCU4	Enterobacteria_phage	6.8e-186	96.4
WP_004152284.1\|60633_61644_+	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_165765869.1\|61977_62265_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004118251.1\|62595_62889_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.7e-49	96.9
WP_004152282.1\|62987_63755_-	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	9.8e-14	25.2
WP_004152281.1\|63755_64712_-	Fe(3+) dicitrate ABC transporter permease subunit FecD	NA	NA	NA	NA
WP_004118243.1\|64708_65707_-	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
WP_004118241.1\|65703_66606_-	Fe(3+) dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
WP_004152280.1\|66650_68975_-	Fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
WP_004118237.1\|69060_70014_-	fec operon regulator FecR	NA	NA	NA	NA
WP_004118235.1\|70010_70532_-	RNA polymerase sigma factor FecI	NA	NA	NA	NA
WP_161989521.1\|71493_71706_-	hypothetical protein	NA	NA	NA	NA
WP_004118231.1\|71634_71802_+\|integrase	integrase	NA	NA	NA	NA
WP_004118840.1\|72086_73214_+	transporter substrate-binding protein	NA	NA	NA	NA
WP_004118229.1\|73210_73804_+	ANTAR domain-containing protein	NA	NA	NA	NA
WP_004152279.1\|73800_74649_+	ABC transporter permease	NA	NA	NA	NA
WP_004118227.1\|74648_75569_+	ABC transporter permease	NA	NA	NA	NA
WP_004152278.1\|75581_77186_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004118225.1\|77230_78178_+	acetamidase/formamidase family protein	A0A1V0S8X7	Catovirus	9.6e-11	22.7
WP_004118832.1\|78185_79919_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.9e-15	29.6
WP_004152557.1\|83741_84089_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.0e-59	95.7
WP_020956879.1\|84085_84472_-\|transposase	transposase	B6DZU5	Stx2-converting_phage	1.1e-58	90.7
WP_004118217.1\|85019_85655_-	His-Xaa-Ser repeat protein HxsA	NA	NA	NA	NA
WP_000005560.1\|85651_86764_-	His-Xaa-Ser system radical SAM maturase HxsC	S5WIP3	Leptospira_phage	1.5e-47	33.8
WP_004118216.1\|86756_88145_-	His-Xaa-Ser system radical SAM maturase HxsB	S5VT21	Leptospira_phage	6.3e-51	29.0
WP_176716597.1\|88144_88384_-	His-Xaa-Ser system protein HxsD	NA	NA	NA	NA
WP_000412211.1\|89352_90012_+	type A-1 chloramphenicol O-acetyltransferase	G3CFL0	Escherichia_phage	8.4e-131	100.0
WP_000656305.1\|90212_90590_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001138064.1\|90656_93623_-\|transposase	Tn3-like element TnAs3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.6
WP_000147567.1\|93625_94186_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	4.0e-49	86.2
WP_000454193.1\|94311_94662_-	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_000845048.1\|94864_95878_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001083725.1\|96022_96520_+	trimethoprim-resistant dihydrofolate reductase DfrA12	A0A0A0PL85	Bacillus_phage	7.5e-23	40.9
WP_001336345.1\|96631_96922_+	DUF1010 domain-containing protein	NA	NA	NA	NA
WP_001206356.1\|96927_97719_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_000679427.1\|97882_98230_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|98223_99063_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000376616.1\|99190_99394_+	hypothetical protein	NA	NA	NA	NA
WP_000184001.1\|99549_100755_+	chromate efflux transporter	NA	NA	NA	NA
WP_000130000.1\|100765_101071_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001389365.1\|101297_102062_+\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
104512:104528	attR	NA	NA	NA	NA

DBSCAN-SWA_4

105400 : 160079

Escherichia_phage(33.33%)

integrase,transposase,protease

attL 107394:107453|attR 138040:138775

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004217321.1\|105400_106105_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
107394:107453	attL	NA	NA	NA	NA
WP_044117068.1\|107408_108077_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.9e-130	99.5
WP_004153729.1\|108932_109760_+	phosphonate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-20	37.6
WP_004152695.1\|109756_110620_+	phosphate/phosphite/phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004152694.1\|110628_111456_+	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_004152693.1\|111464_112475_+	phosphonate dehydrogenase PtxD	A0A1V0SBV6	Catovirus	1.4e-15	25.1
WP_004152692.1\|112468_113338_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000019473.1\|114546_115527_-\|transposase	IS5-like element ISKpn26 family transposase	Q38213	Escherichia_phage	8.9e-185	99.1
WP_004118209.1\|116728_116992_-\|transposase	transposase	NA	NA	NA	NA
WP_004118208.1\|117006_117270_+	hypothetical protein	NA	NA	NA	NA
WP_004152118.1\|117513_117795_+	helix-turn-helix domain-containing protein	A0A1B1IUF9	uncultured_Mediterranean_phage	5.2e-05	38.2
WP_004152117.1\|117829_118399_+	small heat shock protein sHSP20	NA	NA	NA	NA
WP_004152116.1\|118513_121309_+	heat shock survival AAA family ATPase ClpK	K4FB40	Cronobacter_phage	5.2e-129	41.0
WP_004152115.1\|121308_121506_+	hypothetical protein	NA	NA	NA	NA
WP_009483782.1\|121743_122493_+	phosphate-starvation-inducible PsiE family protein	NA	NA	NA	NA
WP_004152113.1\|122479_123442_+\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_020314316.1\|125284_126631_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_003026803.1\|126842_127325_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003026799.1\|127312_127579_-	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_004152108.1\|127754_128009_-	hypothetical protein	NA	NA	NA	NA
WP_004152107.1\|128084_128342_-	hypothetical protein	NA	NA	NA	NA
WP_004152106.1\|128390_128594_-	hemolysin expression modulator Hha	NA	NA	NA	NA
WP_004152105.1\|128627_128996_-	hypothetical protein	NA	NA	NA	NA
WP_004152104.1\|129039_129534_-	DNA-binding protein	NA	NA	NA	NA
WP_004152103.1\|129564_130140_-	hypothetical protein	NA	NA	NA	NA
WP_004152102.1\|130127_130397_-	hypothetical protein	NA	NA	NA	NA
WP_000493378.1\|130966_131317_+	hypothetical protein	NA	NA	NA	NA
WP_000129823.1\|131367_132111_+	hypothetical protein	NA	NA	NA	NA
WP_000015958.1\|132107_132884_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	6.4e-53	92.9
WP_001143775.1\|133155_136161_-\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	99.3
WP_001217881.1\|136322_136880_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	2.0e-93	98.4
WP_063840280.1\|137113_137668_+	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	NA	NA	NA	NA
WP_001067855.1\|138018_138723_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_032409716.1\|139305_139410_-	hypothetical protein	NA	NA	NA	NA
138040:138775	attR	NA	NA	NA	NA
WP_004118283.1\|139939_140806_+	replication initiation protein	A0A222YYK1	Escherichia_phage	1.5e-23	31.1
WP_000339857.1\|140982_141252_-	hypothetical protein	NA	NA	NA	NA
WP_000368714.1\|141666_142872_+	AAA family ATPase	A0A077SL49	Escherichia_phage	2.4e-163	69.6
WP_000064119.1\|142871_143846_+	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	5.0e-87	54.1
WP_001754953.1\|143927_145199_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	5.4e-150	63.7
WP_000776034.1\|145198_145630_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.6e-29	53.3
WP_004178082.1\|146035_147523_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004152753.1\|147756_147987_+	hypothetical protein	NA	NA	NA	NA
WP_004118478.1\|148507_148933_+	antirestriction protein	NA	NA	NA	NA
WP_004152754.1\|149169_149424_+	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	1.2e-11	50.0
WP_004118473.1\|149458_149776_+	hypothetical protein	NA	NA	NA	NA
WP_004178072.1\|150557_150785_+	hypothetical protein	NA	NA	NA	NA
WP_004198570.1\|150876_151107_+	hypothetical protein	NA	NA	NA	NA
WP_004178068.1\|151158_152514_+	DUF3560 domain-containing protein	NA	NA	NA	NA
WP_004152645.1\|152561_153125_+	methyltransferase	A8HNV9	Thalassomonas_phage	1.3e-18	34.1
WP_004152644.1\|153900_154443_+	single-stranded DNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	6.0e-50	76.7
WP_004152643.1\|154491_154740_+	DUF905 domain-containing protein	NA	NA	NA	NA
WP_004178066.1\|154809_156846_+	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	9.0e-22	26.0
WP_004152641.1\|156912_157344_+	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_004152640.1\|157340_158069_+	plasmid SOS inhibition protein A	NA	NA	NA	NA
WP_004199358.1\|158065_158392_+	hypothetical protein	NA	NA	NA	NA
WP_004152638.1\|158447_158822_+	hypothetical protein	NA	NA	NA	NA
WP_004220208.1\|158999_160079_-\|transposase	IS481-like element ISKpn28 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP011991

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 14720

Enterobacteria_phage(22.22%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004227314.1\|963_1179_-	hypothetical protein	NA	NA	NA	NA
WP_004152347.1\|1403_1736_-	hypothetical protein	NA	NA	NA	NA
WP_004152348.1\|2112_3087_-	ParB/RepB/Spo0J family partition protein	Q1MVJ4	Enterobacteria_phage	1.4e-105	62.3
WP_004152349.1\|3083_4289_-	AAA family ATPase	Q1MVJ3	Enterobacteria_phage	7.3e-205	89.0
WP_004152350.1\|4610_5507_-	replication initiation protein	Q71TL8	Escherichia_phage	3.3e-69	53.8
WP_004152351.1\|5907_7179_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	3.6e-154	63.7
WP_004152352.1\|7178_7610_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.0e-28	52.5
WP_004152353.1\|7841_8813_+	mediator of plasmid stability	A0A222YXF2	Escherichia_phage	1.1e-73	46.8
WP_004152354.1\|8815_9487_+	plasmid partitioning/stability family protein	NA	NA	NA	NA
WP_001568040.1\|9547_9778_+	hypothetical protein	NA	NA	NA	NA
WP_004152355.1\|10214_10916_+	DNA methylase	A0A2I7RE86	Vibrio_phage	7.1e-27	36.7
WP_001568042.1\|10915_11137_+	hypothetical protein	NA	NA	NA	NA
WP_001568043.1\|11146_11566_+	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_001568044.1\|11619_12387_+	hypothetical protein	NA	NA	NA	NA
WP_004152356.1\|13066_13495_+	antirestriction protein	NA	NA	NA	NA
WP_001568046.1\|13537_14044_+	antirestriction protein ArdA	G9FHQ1	Rhodococcus_virus	4.1e-08	31.4
WP_001568047.1\|14086_14278_+	hypothetical protein	NA	NA	NA	NA
WP_004152357.1\|14465_14720_+	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	4.0e-12	50.0

DBSCAN-SWA_2

17859 : 28947

Vibrio_phage(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152756.1\|17859_18423_+	methyltransferase	M4M9L8	Vibrio_phage	1.7e-18	42.0
WP_004152654.1\|19253_19766_+	single-stranded DNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	8.5e-54	84.7
WP_004152655.1\|19813_20056_+	DUF905 domain-containing protein	NA	NA	NA	NA
WP_004152656.1\|20124_22134_+	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	1.5e-24	27.4
WP_004152657.1\|22179_22611_+	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_004152658.1\|22607_23330_+	plasmid SOS inhibition protein A	NA	NA	NA	NA
WP_004199367.1\|23333_23657_+	hypothetical protein	I3UM57	Rhodobacter_phage	2.3e-09	34.2
WP_004152660.1\|23767_24127_+	hypothetical protein	NA	NA	NA	NA
WP_004152661.1\|24174_24447_+	hypothetical protein	NA	NA	NA	NA
WP_004153414.1\|24443_24794_+	hypothetical protein	NA	NA	NA	NA
WP_004152748.1\|25423_25777_+	hypothetical protein	A0A248SL90	Klebsiella_phage	5.0e-29	64.2
WP_004152749.1\|25833_26181_+	hypothetical protein	NA	NA	NA	NA
WP_004152750.1\|26275_26422_+	hypothetical protein	NA	NA	NA	NA
WP_004152751.1\|26472_27306_+	N-6 DNA methylase	A0A2K9V411	Faecalibacterium_phage	1.8e-21	33.5
WP_004152492.1\|28125_28947_+	DUF945 domain-containing protein	K4F5L3	Cronobacter_phage	1.2e-44	40.1

DBSCAN-SWA_3

63679 : 68193

Xanthomonas_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152379.1\|63679_64405_+	type-F conjugative transfer system pilin acetylase TraX	A0A1D6ZIU7	Xanthomonas_phage	7.1e-06	28.8
WP_004152380.1\|64476_65070_+	fertility inhibition protein FinO	NA	NA	NA	NA
WP_015060010.1\|65230_65833_+	hypothetical protein	NA	NA	NA	NA
WP_004153014.1\|65882_66527_+	hypothetical protein	NA	NA	NA	NA
WP_004152382.1\|66582_67233_+	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_004152383.1\|67229_67538_+	hypothetical protein	K7PKY8	Enterobacterial_phage	1.1e-08	31.7
WP_014343478.1\|67713_68193_+	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	2.7e-17	31.7

DBSCAN-SWA_4

75828 : 93981

Escherichia_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152392.1\|75828_78858_+\|transposase	Tn3-like element Tn4401 family transposase	NA	NA	NA	NA
WP_004199214.1\|78964_79990_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.4e-87	50.3
WP_004152394.1\|79986_80766_+	IS21-like element ISKpn7 family helper ATPase IstB	A0A2L1IVB6	Escherichia_phage	2.5e-89	61.8
WP_004199234.1\|81053_81935_+	carbapenem-hydrolyzing class A beta-lactamase KPC-2	A0A1B0VBP7	Salmonella_phage	2.2e-73	52.2
WP_004152397.1\|82184_83504_-\|transposase	IS1182-like element ISKpn6 family transposase	Q9MBP7	Staphylococcus_prophage	1.9e-12	24.2
WP_004152398.1\|83780_84965_-\|transposase	ISAs1-like element ISKpn31 family transposase	NA	NA	NA	NA
WP_004152400.1\|85468_85828_+	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	3.6e-19	62.0
WP_004152401.1\|86484_86895_-	hypothetical protein	NA	NA	NA	NA
WP_004152402.1\|86993_87614_-	recombinase family protein	A0A219Y912	Aeromonas_phage	2.0e-09	31.5
WP_004152403.1\|87702_90600_-\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	2.7e-181	37.7
WP_001067855.1\|90672_91377_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000027057.1\|93120_93981_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0

DBSCAN-SWA_5

97208 : 98903

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000105636.1\|97208_98903_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	8.8e-39	27.6

DBSCAN-SWA_6

104029 : 107887

Macacine_betaherpesvirus(50.0%)

integrase,transposase

attL 100982:100995|attR 106029:106042

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
100982:100995	attL	NA	NA	NA	NA
WP_004152340.1\|104029_104812_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	4.6e-51	90.2
WP_004152341.1\|106025_106499_-	YkgJ family cysteine cluster protein	NA	NA	NA	NA
106029:106042	attR	NA	NA	NA	NA
WP_004152342.1\|106618_107887_-\|transposase	ISL3-like element ISKpn25 family transposase	Q6V7R1	Burkholderia_virus	5.2e-60	34.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP011992

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP011989

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP011990

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. NZ_CP011991

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection