CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_021658	Sorangium cellulosum So0157-2, complete sequence	65 crisprs	cas3,csb2gr5,csb1gr7,cas1,cas2,csa3,RT,DEDDh,WYL,DinG,PD-DExK,cas6	12	41	3	0

1. NC_021658

CRISPR-Cas detection and classification

Crispr_ID: NC_021658_1

• CRISPR_ID: NC_021658_1
• CRISPR_location: 609428-609705
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 6 spacers
• Cas_protein_info: cas2,cas1,csb1gr7,csb2gr5,cas3,cas8u1

Consensus repeat of NC_021658_1

Consensus_repeat	Method
GGCGAGCGCGCTCGCGGGGG	CRT

spacers of NC_021658_1

>1.1|609448|23|NC_021658|CRT
GACCAGGTCGCGTCGTGGTCGTT
>1.2|609491|23|NC_021658|CRT
ATCGGGACGCGCTGGCGATCGCG
>1.3|609534|23|NC_021658|CRT
GACCAGGTCGCGTCGTGGTCGTT
>1.4|609577|23|NC_021658|CRT
ATCGGGACGCGCTGGCGATCGCG
>1.5|609620|23|NC_021658|CRT
GACCAGGTCGCGTCGTGGTCGTT
>1.6|609663|23|NC_021658|CRT
ACCGGGACGCGCTGGCGATCACG

CRISPR arrays and Neighbor proteins around NC_021658_1

CRISPR arrays

The CRISPR arrays of NC_021658_1

>merge|NC_021658|1|609428-609705|CRT
GGCGAGCGCGCTCGCGGGGGGACCAGGTCGCGTCGTGGTCGTTGGCGAGCGCGCTCGCGGGGGATCGGGACGCGCTGGCGATCGCGGGCGAGCGCGCTCGCGGGGGGACCAGGTCGCGTCGTGGTCGTTGGCGAGCGCGCTCGCGGGGGATCGGGACGCGCTGGCGATCGCGGGCGAGCGCGCTCGCGGGGGGACCAGGTCGCGTCGTGGTCGTTGGCGAGCGCGCTCGCGGGGGACCGGGACGCGCTGGCGATCACGGGCGAGCCCCGCCTCGCAGG

>NC_021658|1|1|609428-609705|CRT
GGCGAGCGCGCTCGCGGGGG	GACCAGGTCGCGTCGTGGTCGTT
GGCGAGCGCGCTCGCGGGGG	ATCGGGACGCGCTGGCGATCGCG
GGCGAGCGCGCTCGCGGGGG	GACCAGGTCGCGTCGTGGTCGTT
GGCGAGCGCGCTCGCGGGGG	ATCGGGACGCGCTGGCGATCGCG
GGCGAGCGCGCTCGCGGGGG	GACCAGGTCGCGTCGTGGTCGTT
GGCGAGCGCGCTCGCGGGGG	ACCGGGACGCGCTGGCGATCACG
GGCGAGCCCCGCCTCGCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020465165.1|619578_620664_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080681936.1|616042_616180_+|DUF3368-domain-containing-protein	unknown	unknown	gnl|CDD|378736
NC_021658.1|WP_020465163.1|614751_615693_-|IS1380-family-transposase	unknown	unknown	gnl|CDD|379340
NC_021658.1|WP_148313247.1|631648_632188_-|hypothetical-protein	unknown	unknown	gnl|CDD|237874
NC_021658.1|WP_020465154.1|598025_598988_-|hypothetical-protein	cas8u1	mkCas0114_cas8u1_CAS-I-U	unknown
NC_021658.1|WP_020465159.1|607554_607845_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
NC_021658.1|WP_020465158.1|605490_607494_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187766
NC_021658.1|WP_020465168.1|628206_629220_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381378
NC_021658.1|WP_020465155.1|598984_601984_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	gnl|CDD|274235
NC_021658.1|WP_148313246.1|616498_618202_+|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|224511
NC_021658.1|WP_044985453.1|618198_619404_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_148314691.1|596141_597131_-|radical-SAM-protein	unknown	unknown	gnl|CDD|234672
NC_021658.1|WP_148313245.1|607885_609076_-|hypothetical-protein	unknown	unknown	gnl|CDD|235562
NC_021658.1|WP_020465161.1|609171_609348_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080681937.1|623232_628152_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_021658.1|WP_020465166.1|620715_622275_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_021658.1|WP_020465157.1|603667_604945_-|type-I-U-CRISPR-associated-protein-Cas7	csb1gr7	pfam09617_csb1gr7_CAS-I-U	gnl|CDD|378223
NC_021658.1|WP_020465170.1|629696_630821_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020465153.1|597214_597961_-|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_021658.1|WP_020465156.1|601976_603668_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	gnl|CDD|274005

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_021658.1|WP_020465155.1|598984_601984_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	2e-136	450.6	5.0
NC_021658.1|WP_020465156.1|601976_603668_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	2.9e-90	298.3	24.7
NC_021658.1|WP_020465154.1|598025_598988_-|hypothetical-protein	cas8u1	mkCas0114_cas8u1_CAS-I-U	3.5e-96	316.9	0.0
NC_021658.1|WP_020465159.1|607554_607845_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	6.6e-21	69.2	0.0
NC_021658.1|WP_020465157.1|603667_604945_-|type-I-U-CRISPR-associated-protein-Cas7	csb1gr7	pfam09617_csb1gr7_CAS-I-U	3.6e-29	96.7	0.0
NC_021658.1|WP_020465158.1|605490_607494_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	3.8e-109	359.2	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_080681936.1|616042_616180_+|DUF3368-domain-containing-protein	gnl|CDD|378736	pfam11848, DUF3368, Domain of unknown function (DUF3368). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is about 50 amino acids in length.	7.22957e-06
NC_021658.1|WP_020465163.1|614751_615693_-|IS1380-family-transposase	gnl|CDD|379340	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	1.80719e-23
NC_021658.1|WP_148313247.1|631648_632188_-|hypothetical-protein	gnl|CDD|237874	PRK14971, PRK14971, DNA polymerase III subunit gamma/tau.	0.00210829
NC_021658.1|WP_020465159.1|607554_607845_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	1.05376e-18
NC_021658.1|WP_020465158.1|605490_607494_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.66928e-115
NC_021658.1|WP_020465168.1|628206_629220_-|aldo/keto-reductase	gnl|CDD|381378	cd19152, AKR_AKR15A, AKR15A family of aldo-keto reductase. The AKR15 family includes Microbacterium luteolum pyridoxal 4-dehydrogenase (PLD), Pseudomonas sp. D-threo-aldose 1-dehydrogenase (FDH), and similar proteins. PLD (EC1.1.1.107) catalyzes irreversible oxidation of pyridoxal. FDH(EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose. FDH (EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose.	1.57712e-142
NC_021658.1|WP_020465155.1|598984_601984_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|274235	TIGR02621, CRISPR-associated_helicase_Cas3, CRISPR-associated helicase Cas3, subtype Dpsyc. This model describes a CRISPR-associated putative DEAH-box helicase, or Cas3, of a subtype found in Actinomyces naeslundii MG1, Geobacter sulfurreducens PCA, Gemmata obscuriglobus UQM 2246, and Desulfotalea psychrophila. This protein includes both DEAH and HD motifs.	4.48593e-119
NC_021658.1|WP_044985453.1|618198_619404_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	4.04276e-07
NC_021658.1|WP_148314691.1|596141_597131_-|radical-SAM-protein	gnl|CDD|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	1.56015e-09
NC_021658.1|WP_148313245.1|607885_609076_-|hypothetical-protein	gnl|CDD|235562	PRK05687, fliH, flagellar assembly protein FliH.	0.00274593
NC_021658.1|WP_148313246.1|616498_618202_+|RNA-polymerase-sigma-factor	gnl|CDD|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	2.70267e-12
NC_021658.1|WP_080681937.1|623232_628152_+|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	2.53521e-153
NC_021658.1|WP_020465166.1|620715_622275_-|sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.04969e-44
NC_021658.1|WP_020465157.1|603667_604945_-|type-I-U-CRISPR-associated-protein-Cas7	gnl|CDD|378223	pfam09617, Cas_GSU0053, CRISPR-associated protein GSU0053 (Cas_GSU0053). This entry is found in CRISPR-associated (cas) proteins in the genomes of Geobacter sulfurreducens PCA and Desulfotalea psychrophila LSv54 (both Desulfobacterales from the Deltaproteobacteria), Gemmata obscuriglobus (a Planctomycete), and Actinomyces naeslundii MG1 (Actinobacteria).	5.49888e-59
NC_021658.1|WP_020465153.1|597214_597961_-|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	1.46818e-10
NC_021658.1|WP_020465156.1|601976_603668_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6	gnl|CDD|274005	TIGR02165, CRISPR-associated_protein_GSU0054_family, CRISPR-associated protein GSU0054/csb2, Dpsyc system. This model represents a CRISPR-associated protein from the Dpsyc subtype (a type I-C variant), named for Desulfotalea psychrophila LSv54. CRISPR systems confer resistance in prokaryotes to invasive DNA or RNA, including phage and plasmids. CRISPR-associated proteins typically are found near CRISPR repeats and other CRISPR-associated proteins, have low levels of sequence identify, have sequence relationships that suggest lateral transfer, and show some sequence similarity to DNA-active proteins such as helicases and repair proteins.	4.49392e-48

Protein sequences

>NC_021658.1|WP_020465161.1|609171_609348_+|hypothetical-protein
MLDFDHDVEVDRDVDVERRQLVHIAELAAFLRARTPVQAPEPGEGSHAGRADVRRHEL
>NC_021658.1|WP_148313245.1|607885_609076_-|hypothetical-protein
MSTRKRAFASAPRIAAKQSGDRNRGGGSPARNAGNTISAQPRRGARNTAAPAPLRTWRPAPSLRKNSTRCAEIGLPTRSTNPMLATASRRGRFDAFGKNVLRETLDLVGGADMQVEVIATSQTMDIWYVPDPARAALRAELGLLGELAAEPCQFEPFHDTPGPAELRDCVRKQLHWHHELERRAGGPVPFPRLCVLSSGRPATVLDAFGFDPVPGRPGLYRAAPGWRIDVVVIAELPRTRDTLLLRLLGARAVLRDAIRELIALPDDAWERGIALPWLLRLRFEVPADPSARTQEEAEEEEIVTEVQQWFEQLKQTLRDEARKEGLTEGRKEGLTEGQLRVLAAQFEKKLGRPLTEAEHPVLAERLDRLGSDRLDDVRLGLSADALTAWLADPAAR
>NC_021658.1|WP_020465159.1|607554_607845_+|CRISPR-associated-endonuclease-Cas2
MRQSYIVSYDVCDPKRLRKIFKAMRGYGDWLQLSVWQCELSRRELVELRRDLGQIIDAKVDQVLIIDIGPANGRGLSAIASLGRAYVPSERVAVVV
>NC_021658.1|WP_020465158.1|605490_607494_+|CRISPR-associated-endonuclease-Cas1
MARAPERVTDESSEPLIRAKPLPRRLPVAGTPPELVPARMINEVLYCERLLYLEWAQGEFEDNVFTVEGRSVHRRADVAGGELPPRPAGAAQGAGAEQAEVAASPAQPRRAPGRRADRDEEGDEPAPYEARSVWLSSERLGITAKIDVVEGDASGRLLPIEYKRGHAPDVPGGAYLPERAQLCAHVLLLREHGYSCDEAAVYFAASRRRVSIAIDDALIAATHAAAARAREVTRAAAIPPPLVDSPKCNGCSLVGICLPDETNLLRRLDGEDLDAAAASEGPPLEAGGSAELEGPLEVDPWGIAGAAAVDERVVEDSDDERGVELRRLHPARDDKVPVYVQEQGARIGLAGERLVIHTRTGGQTEARLSNTSQVALLGNVQISTQAMRALLERGIPLLLMTYGGYYLGRATGLESRNVELRVAQHRAAADEAFCLSFARGVVVSKIKNARTMLRRNHASPEAAVLSELDQLARKAAEAPSLPSLLGIEGTAARVYFGAFAGMLKAAGEVRGEFDLEGRNRRPPRDPVNALLSLAYALLAKELATTLGTVGLDPLLGFYHQPRFGRPALALDLMEEFRPIVADSVVVAAINNGVVAPDDFQRFGDAVALRPAGRKKFLLAYERRMDQLVTHPVFGYRISYRRVLEVQARLLARVLLGEVGAYPSFRTR
>NC_021658.1|WP_020465157.1|603667_604945_-|type-I-U-CRISPR-associated-protein-Cas7
MRSLDLDTLANAVAGGAAAIRAITRLEPAGGPGDKVFPPTYVKERNATTKYATEQRRIDGREVTTVLLDSVASQANRFEEALLDGFRRGELPFPIVQVDFSNEAGLADLEQITALQAPHRIADALLRDSVLGGTPFRHTAVGKEVTDARPTHATAMFKYCPTALIFGVWDSTGPKGGLGAKFQRCLVSEIVGIDIATGVKTASRLDPAGIQTKAGPVFKHKDPSQDWTVDPKEAELAKGGKPVEFSRSGGDGKKGSPSAINHGNIPPSIDAAAGGVTMSHAVQTTVLSLGALRRLRFQTACSGERLPTEQRDAAETAARTALAALGLAAVVYQRDQGYDLRSRSTLVAKEPLVFELVGRDGGEPERFSLSRAEAAALLKGAEQKARKLGLGWDAKPITLTPAPKLAGLIRKSRELAASGEAEDEG
>NC_021658.1|WP_020465156.1|601976_603668_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6
MLAIEVALLTGRYVATAVDDRDRAEWPPHPARLFSALVAAYFDTLDPSADERAALEWLEQQGPPEITAPEAAAREVVTVFVPVNDTSVVGSLDDEALTVREARAELDAARPAGGKPLAAAEKKLVKAEARFLEAVRKAIAPVPAGKEGKDGPVKATSILPERRTRQPRTFPSSAPAEMEPAMPRIVFAWPSATPTPEQRAALDALAARVTRLGHSSSLVTARVRDDRPEATWIPDDTGPGRAGDEAVLRVVGPGQLAALGAAFELQADTPGRVMPASFQRYVRPRAASEASAPAPLFGDGWIVLRRVAGPRLPSIRAVDVARTVRKAMMAAYGPGAPEILSGHRASGGPSERPHLAYVPLPFVGSEHADGALLGVALILPRDVTRDERLAIYRALDAWEQQARGGDEEPPRLPVHLGKAGELMLERLEEQTSATTLRPATWCAEAASWASATPVALDRNPGDLGARDPQKEAAAYAEAEATLAVACERIGLPRPSRVTVMPAAPLAGADKARRFPPFHAGKPPVQRVLVHATLTFDAPVRGPILLGAGRYFGLGLFRPLRANG
>NC_021658.1|WP_020465155.1|598984_601984_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3
MAELSPDDFAAYFEAIHGAAPFPWQARLLADVAREGGWPTLLDLPTGAGKTAAIDVALFHLALDAAAPPAQRTAPRRIVMVVDRRTVVDQAFERAKKIAETLTGAGNGVLRAVADRLRALAGLRGNEAPLALAQLRGGMPRDDAWARRPDQPLVAVSTVDQVGSRLLFRGYGVSDAMRPIHAGLLGNDTLLLLDEVHLSQPFRETLRSLCRYRTWTSRKLPDRWQVVEMSATPGSTAGTAGVTSAASDDGRVFGLNDDDRRDERLARRLQANKPAALAEVKVSGGEGARRAALAEACAEHALRFVAPGRAVGVIVNRVATAREAAEAIRKRSGGSVDPILVTGRMRPLDRDDLDERLGPLVRTGRARDAAADPVVIVATQCIEAGADFDLDAIVTECASIDALRQRFGRLNRIGAIEDARGVVLVRSDALAKDYVDPVYGNALAATWTWLGEATRDFGIQEMAAALPEGARLEAMLSQTSRAPVMLPAHLDAWVQTRPSPEVDPDVSLWLHGTDQEHAPEVQVVWRADVTGTLLAQAKRDEEAREALLKRVEACAPVGLEAISLPIHAVRAWLQGGAAPELADIEGRAMDDDEGDRHDGRLALLWKGDESRVIEPGELCPGSTLVVPGTYGGLAGGTWDPSSQVPVSDLGDRARWQQTGRPTLRLHPDVMRQHAGVTDAALPKIPVPVVDERSDAQDRAEIDAWLSEMSAATAATSWLGQVITALAVKGRRRPALVRLDGMELVGEDGAPRVEEGYFALVGRFRTRVEGAGDVTTEDDGASYTGVEVTLREHLGGVASWARRFAEQCGLPPEVARAVELAARWHDAGKVDPRFQRMLHGGSELRAAVAPEPLAKSALVAADRAARAHAIKRSGYPRGARHELSSVALLQGCERLFDKDVDRDLVLHLTASHHGWCRPFAPVVADDEPVELALEVEGTPVRVSSDHGLARLDAGIAERFWRLVQRYGWFGLAWLEALLRLADHRRSEEEQRGDIGARDDR
>NC_021658.1|WP_020465154.1|598025_598988_-|hypothetical-protein
MTELLLTGLDGKNPLAFLAALGVLNALADRTKDGTPEPRLVWRAGGTYQPAIMGGPDRGALLDVLVQDLASFRGEPAIEWLHYRKDGDGAEAHDLKPPPGFFVDYLSRLLGDCPSRGVSDELRRSLAFAAAFATDVAVDNNGNTKPTALHFTAGQQEFLTMVSELIQGVRVEDLEEALFGPWRYERPLPVLQWDNTSARDYALRASDPSKDKKLGVPGADWLAFRGLPFIRVAPVGDRIVTTGCSGEWKTGTFRWPIWTVPLSRPVIGSVLTSSEVFEVDPGVLRARGIAIVFESAIRRSDQGGYGSFAPARMARPARAG
>NC_021658.1|WP_020465153.1|597214_597961_-|radical-SAM-protein
MPTATRPQNATLTGALPLDRPTAERPHRLYVATTNHCNRACPWCCTCSSPRGRTFLALDRYRASFPPEGPFEVQLEGGEPTIHPHFDEMVRLARAEPRCARVVVVTNGVEIPRDPAALDAWLQKLGEPTTLKLSINHHLLEHDSGLLPLARAIHARLAALGGDRQLVLNVRLRKTEADGDAWVVEAVRDAGLLAIANVFHLQRYGFAQKREDWDEPFLVGTHFTMLNPDGRAFGPDLVARSDAMRGLP
>NC_021658.1|WP_148314691.1|596141_597131_-|radical-SAM-protein
MRFDLWGRPVEIYRNANFSIYSRQPCNAKCHFCVEELRPASRGRSLSLQKTVEDDDARYFDAMAESLDALRPLDPTVSITGGEPSHDPRLPRILALGQARRGRKRTLTTNGSGLLQRRDGKRVIDWIADTGVQHLNISRAHPDHDTNARLMVMKDGLSVDELRSVVSAAAAGGTRVRLSCVLLAGQIDSVDAIVSYLRFARSLGVDNVIFRQLMKTDPTAVVENHVVKYSDRSRVRLEPILDALSADARFSFERQIVGYYYYVEVFRFEDIDVVFEEADLAQLEETKRSGPGIVHELIFHPNARLASTWQPWDGILGPPPAARGSVDPS
>NC_021658.1|WP_020465163.1|614751_615693_-|IS1380-family-transposase
MLVDHGLALVARRKHRFVHIDVDTTVEPLFGMQEGALPGPNPRYHGRPSYHPILARVAEVDAIVGAKLRPGDTSFGEADVPFVEECIDRARAAAPSAVIYVRIDGAGDCSALMHAVAMKGCFFLTKARMSPDLVGMVAHATGWRTIDWDADGRPRRQVAEVPFRCSDWPDSVRVIAVRTRDRENGKQIYLWEGLDYTVQVFLTNEPVEAPEDVAARYDLRAGIEPLIGDLKHGWGCGRVPSHSFNANHAALLLKLLTANLMRRYVLDHVPHLASWRTPWLRRALILVPGRLARSARGTKLHVPERSQLARWLN
>NC_021658.1|WP_080681936.1|616042_616180_+|DUF3368-domain-containing-protein
MGLLVEARRAGVLGSLRAVLDDLANAGFRVSALLVTEALRQVGEE
>NC_021658.1|WP_148313246.1|616498_618202_+|RNA-polymerase-sigma-factor
MSPLSPPPPPPPPALPPPPPDLVQHSTWASMHATAVHVLPGMLRYLGVAQGDIDDLSQEVLLGAYISLPRYDPHYPAGAYGAPFPPPSSASPLHDLVFAAVPVSIAAAAAAAAADPADPSEPAYDPASPPLRFPPALSSRSRPAHLGPRWRSESAWLFGIAWRKVRSHLERAYRRREVPVGLADAACFEGAEVAPSSEQRVVRKERIALAIRLLASIAPERRAVLLMADAYEIPMREVARALEINENTAASRLRLAREDYRAAVKRLRAEEQHALRSRLLMLPLFSLASASSASSAAPARAVLAGASAIAEANAPATLPSPRSDPGRHDPADRPRNPARSARFARVAHLARPLARFVRPALARGTAAIVGAAVVVAALAPAPVSWANRLAPIATQLVAARAAHAGARPETDPGEPPRSKAPPRDALAAIPAKETSAVRTPPPALPPPAPADGSGHLKPAAPRQHASSERRQDPLTEEILLLEAVRQALVQGDRATAMERIAAHERRFPQGRLKLMRERLRAKMDPAQPAPAGNPTQPAPAGNPTQAAPAGNPTHPVPAGNASREMLP
>NC_021658.1|WP_044985453.1|618198_619404_+|hypothetical-protein
MTARTRRARRTPRGQSAITNAIATWFQRAALAAMTAAAIAILGIAPVRAEPRATPTRVRLEFLRGPGAEECPDERFLREQTIRRLAGVDPFDAAAPLTLTASIERQRGELAAALFLRDRSGRGLWADGFSARVDCEVLVSAIALSIAVLLDGDELPAMSGATPDLPAAPGAPPAPPQPTDKAMVPGPPCSPDRPCPPQPAPAPVSPSQKTPPPRKTPPPRKTPPGSSAPPAPSERFRWVAGLDAVAGLGLTPGVSLGSAMSIGARWPAWSAALEVRGLSSLPGKIDAVDMSVSTITANIVPCLNRRTVFACGLAELGVVRTAPSTPFDVASRLRFRAGLGARAGIAWPLAENLSMRAHAEIVHPVIGAALLRHPGVPVRERPMWSALALGAALGIGLQVSL
>NC_021658.1|WP_020465165.1|619578_620664_+|hypothetical-protein
MLLIAGCELEPVIITGPCTQEEIDLGYCDVPDAGTTSTGGDGGDAGAGGQGGAGGDTHSSLCSGQCAPPAPLGWFGPALLWFGPSEAVPDCPADAPTLGYEGFADLQQPPLECATCACDPPDASCSLPTDWAAASSSSCPGDEPGTVTTSFAAPDGWDGACTAANAIPADHLCNGEPCVQSLTIAAPSVVTTGACTPREDVPPPIPRLDPWATRARACLAGAYTACDDATTCVPSAPSGFTTCVFHEGDDADCPDGYAVRHLFFADVIDGRDCTPCGCGDPTGASCTLMASVYRDAACTDLLASNVVSSSVPFCVVTPPGVALGSKSAVIATVEPGRCAPHGGEPVGELRPSAPSTFCCIA
>NC_021658.1|WP_020465166.1|620715_622275_-|sensor-histidine-kinase
MDDAGPPLTSSLAARLRSCKRAVIERWTRRVLDDPRAMAKQHGGPLLADEVPRLFDDLIEALAASRRAELRAGEDGEPASAHERIEDQARLHAAQVRCIAATLRELSHLRAALIEVCAAQGICLGVREAQVLHAVVDASMWTSAREIETATRAALEDSAARLRLATEAGGVGVWDYDTVTGALRWDDRCRQVSGVGPEQDVDYELFVSAIHPDDRARVQEAVLRSQDPASGGEYNIEYRLVGLRDGIERWVCVQGRACFDAAGRSVRMIGTVIDISERKRAEAARREELAFRDRFLGALGHYLRTPLTSVTLATSVLMHHGNLTPGQAKSVERIAASARRMGRTIEDLLDLTRSRFGGSIPIAPSPGDLHLICKGAIDELGAMHAGVPIRLDLHGSGAGQWDPERVAQMVTNLVQNAVDYAAPGSAVRVAIRPRGDDVLIEVHNDGPAIAPELLATLFDPFHQAMVGGRTSSGRGLGLGLFIAHQIARAHGGGIEVESEAERGTTFTARLARGAAEARC
>NC_021658.1|WP_080681937.1|623232_628152_+|AAA-family-ATPase
MTTRRPGVERGTARINGYQITAKMGETAASVTYRARREGDGREVAVRMLHADLSRIADVTRFKHACSAIRRIDSERIVKVHGVEEHADGLLLVTEYFPGAALSELLKDRGELDVGGFLSGAIRMTEAVADIHRRGLLHGDIRPRNILLGEGGQIKLTGFGVESIVTREREAIYGREVLSEVLPYTSPEQTGRMNRSVDYRADLYSLGVVFYEILVGRRPFEAADPLELIHAHIAVKPTPPSELNPKVPPALSAITMKLLGKNAEDRYQSTEGLKDDLEECRRRWEERGAIDDFTPGQHDRTDLFQIHQKLYGREGDIRRLIESFDDVLRGRRAIVLVSGYSGIGKSSLVQEILKPLARERGYYVSGKFDQYNRDTPYSAVVHAFDALVKQLLSESEERVQRWRRAILDALGSNAQVICDVLPSLGHLIGAQPAVPALGPVEAQNRLNLYFKKFVAVFARPAHPLAVFIDDLQWVDSASLSLLKSLLADEGMESLFFCGAYRDNEVSPTHPFLVALEELQAARLGVVDIVLEPLRLAHLSELLSDSLRTGGTDALARAVLKKTGGNPFFVKQFLRHLVEVRALVLDPAAGWRWDLSTIKELEHTDNVLSLMAQTIRRLPEDTQEVLRLAAAIGNSFALEILNTVSAEAPDATYGSLARAIDDGLIVSAGEGYRFAHDKIQEAAYSLIPARDRPGFHHRIGRLLLGKLDPDDGQSVFEVVNHLNSAGDLIQAPEERLTSARLNLRAAARAEESSAFSASLKYLEHGISLLPADAWTSEYELTFAYHTKKGVLESLCERHDDALATLSGCLDKARGRVHETEVRRLKINVQILKNDLPAALDEGLAALRAFGIDLPPYPDDALLTAEIERTMALIGDRPIASLIDLPALADPEIAALQDLLQEMFSPTYQLGTNNFGITVMKMLQNTLTHGISRNSIYAYVNFGTILCARLDVERGYEFGRAAVRLNELNPDKKSEAMLCNMWGAWVQHWRESYATYKASLRKGMHVGLETGQYIWAFYNACNSQLSSLLLGKNLHELVQEAKDSEHICKLDRFNAITWIVAAAADLGEELSTPAEGDGDRPRARRVDLDAIIAEARRINNTASLYFTNIFTVIGGVFKGEHERVAAVWGETDPGADVMLGAWHASPCYYFYGGVASSRASTAAAPALGSAYVERLRAFAGKLDLWAGLNPQIFLHRSLILRAELARIERREGAGALYDQAITAAREARLLHDEALANELCALHYRDMGREFLAHAYIAEAHRLYARWGAARVTERLERDFPQALGREAPRQAGAGDHAGAAQRASLDHAAEADHGKAKLDTLAVIKASQAISGEILFPSLLKKLMQSILESAGARKGLVILRDNDRLVVQAEGHVEAREIKVLSPVPLEACGDVAASVVHYVTRTAESVVLGDAASSDLFASDPYIARTQARSILAAPILRQGRLVGVIYLENDLAAGAFTPDRLEVTRLLAAQVAISMENALLYASLEEKVRTRTAELEVAHERIEIELSEKLALIARQRELIRTLSTPILEVWDGVLTIPVVGGLDDDRASTIMQDLLERVVDTQSRSTIIDLTGVSAIDPGSAERLVRIIRSVQLLGSRSIITGIQPQVARTMISHGLDLSRVTTRAKLRDGLRMCMG
>NC_021658.1|WP_020465168.1|628206_629220_-|aldo/keto-reductase
MKLKDILPGKLGFGTAPLGNMFRDIPEAEARATVDAAWDDGIRYFDNAPFYGAGLAEIRMGEALAGRPRQDYVISTKVGRVVLDQVEDVSARDLGEKGGVFKHGRPNKVVNDYSADATSRSIEGSLERLKTDHIEIVWVHDVAQDFYGDEWLGVFESARKGAFRALDRLRDEGVIKAWGLGVNRVEPIELLLALEEPRPDGFLLAGRYSLLDHERALQRVMPEVAARGLGIVVGGPYSSGALVGGPNFEYAPATPEILDKVARIKTIADRHGVSMKAAGLQFALAHPAVAAVIPGASRPGRIAEDRAALNEVVPADFWRELRRADLVSPAAPLPIAD
>NC_021658.1|WP_020465170.1|629696_630821_+|hypothetical-protein
MGGADDVSTHGAGDNSAAILGGTVDAPVDDDGAPPWARPPTREEAEAILERVVALYQDHAAAANPAGTHEISWRIDWDSDAVSAHVLLNRGEDWTIEVSKGWLTASSMTAEVFALTMCHEMGHFIGGFPFKTSGRGDSTGALGTSVAAEGQADYFATKDCLPRLRANETEANAAAFAELDPSARERCTTAYGDLASQQLCGRILRASLQTGRLYEEQEVLQAPRELVYPRFDTPDTTEVAVTKEGHPTSQCRLDTLVAGAVCSVKATGTEIPGFVPPYGEYSDASEEAARPFACQTGPGARPRCWFQPDTVATDCSELGEQACVVEEGRTGVRYCDTTFGVTYYWCFGDEVCKTSRDGFSDCYAPDVDPDEGSF
>NC_021658.1|WP_148313247.1|631648_632188_-|hypothetical-protein
MAAGAMLEGGATGSACGGRTGAWATGEEDGGPAGESPAASVVIAAGSKPSAMTSAAAPASASHVGAPSARSPAPSGLSVRSVSEKPPSPVRVTCALATSRCLPFVRGFPPRRRSISWSTAALEGHVSGACHESEIGCSCAAAVRTVSATQRKEAAVRTRRQRIMNAKPHTSANRGHLVG

Crispr_ID: NC_021658_2

• CRISPR_ID: NC_021658_2
• CRISPR_location: 610407-614614
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 57 spacers
• Cas_protein_info: cas2,cas1,csb1gr7,csb2gr5,cas3,cas8u1

Consensus repeat of NC_021658_2

Consensus_repeat	Method
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CRISPRCasFinder
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CRT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	PILER-CR

spacers of NC_021658_2

>2.1|610443|36|NC_021658|CRISPRCasFinder,CRT
CCCTCGGGGTCGAGCCTGCCCCAGTGGCTCAGCACG
>2.2|610515|36|NC_021658|CRISPRCasFinder,CRT
ATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCC
>2.3|610587|36|NC_021658|CRISPRCasFinder,CRT
ATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCC
>2.4|610659|36|NC_021658|CRISPRCasFinder,CRT
ATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCC
>2.5|610731|39|NC_021658|CRISPRCasFinder,CRT
GCCAGCACGCCGCCCTGCCCATGACGCCCGAAGCCGTGG
>2.6|610806|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
>2.7|610878|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GCCGTGGCGCTCGCGCTTGCGGCGGCGCCGAACGAG
>2.8|610950|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TCGTCGATTCGCGGTCCAGGTCACGCCCGAGTTCCGGC
>2.9|611024|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
AAGTGCACGTATACTCTTCGCTGACTGGCTCACCCA
>2.10|611096|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
>2.11|611170|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
>2.12|611242|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
>2.13|611314|39|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CAGATCGAGCCATCCGACCAGGAGGCGGGGGGATCCGAT
>2.14|611389|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TAGACCTGGCGAACGTTGCCAGTGGCCTCGACGATCTT
>2.15|611463|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TCGTCGATTCGCGGTCCAGGTCACGCCCGAGTTCCGGC
>2.16|611537|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
>2.17|611611|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
AAGTCTCCGGTGTTAAACATCCGCTCCTCTGCCTCG
>2.18|611683|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GACCACCGCGAGCACGCTTCCGCCGCCCGGAATCAC
>2.19|611755|39|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGCTGTTCCTTGAGCCACCGCTGGACGAGGGCGATCCCG
>2.20|611830|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGCTCTGCGAACAGCACGGTCGGAGAGGTGTGTTTGA
>2.21|611903|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGTACGTCAGGACGTGGGCGGAGGCTCTCTTGCCCGA
>2.22|611976|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ATCAGCTCGCGCCGATGCGCAACGAACAGCGACCGA
>2.23|612048|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
>2.24|612122|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
>2.25|612196|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
>2.26|612270|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
>2.27|612342|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
>2.28|612414|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CTCTAAGGTCGTGTTCGATGCCGGAGCCTTGCTGG
>2.29|612485|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GATGGCATGCGTAGGAGGGACGAAAAATCCCTGCATC
>2.30|612558|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
>2.31|612630|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
>2.32|612702|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GTAGGACGCCCGGATTACGCGGGCGAAGCCTTCGGA
>2.33|612774|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
>2.34|612848|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
>2.35|612922|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
>2.36|612994|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
>2.37|613066|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
>2.38|613140|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGGAGAGGGGAGCGCTGCGTAATGGCCCTGCCGCGCG
>2.39|613213|41|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TGCAAGTTCGGGGAGCTCCCCGTGCGCCCTGTTTCCTTGAG
>2.40|613290|41|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TGCAAGTTCGGGGAGCTCCCCGTGCGCCCTGTTTCCTTGAG
>2.41|613367|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
>2.42|613441|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
>2.43|613515|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
>2.44|613587|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TTCGATCTGCCGGAGAGCGTGTACGACGACGCGGT
>2.45|613658|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TTCGATCTGCCGGAGAGCGTGTACGACGACGCGGT
>2.46|613729|39|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ATACGGTCCGGGTCTTCAAGCTCTACGTTGTAGCAGGGC
>2.47|613804|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
>2.48|613878|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
>2.49|613952|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
>2.50|614026|39|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GCCAGCACGCCGCCCTGCCCATGACGCCCGAAGCCGTGG
>2.51|614101|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
>2.52|614173|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ATCGCGCAGGCCGCGACGGGCGGCGCCGCCACGGCC
>2.53|614245|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
>2.54|614318|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
>2.55|614391|40|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TCCTATGAGGGAAGCGGCAATCGGGCCCGCTACGTGATAG
>2.56|614467|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
>2.57|614541|38|NC_021658|CRT
CGTTGACATGTCGGTCGCGGCCGGCGTCGCCCAGCGAT

CRISPR arrays and Neighbor proteins around NC_021658_2

CRISPR arrays

The CRISPR arrays of NC_021658_2

>merge|NC_021658|2|610407-614614|CRISPRCasFinder,CRT,PILER-CR
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCCCTCGGGGTCGAGCCTGCCCCAGTGGCTCAGCACGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCCCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCCCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCCCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGCCAGCACGCCGCCCTGCCCATGACGCCCGAAGCCGTGGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGCCGTGGCGCTCGCGCTTGCGGCGGCGCCGAACGAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTCGTCGATTCGCGGTCCAGGTCACGCCCGAGTTCCGGCCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCAAGTGCACGTATACTCTTCGCTGACTGGCTCACCCACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCAGATCGAGCCATCCGACCAGGAGGCGGGGGGATCCGATCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTAGACCTGGCGAACGTTGCCAGTGGCCTCGACGATCTTCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTCGTCGATTCGCGGTCCAGGTCACGCCCGAGTTCCGGCCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCAAGTCTCCGGTGTTAAACATCCGCTCCTCTGCCTCGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGACCACCGCGAGCACGCTTCCGCCGCCCGGAATCACCTCTCCGCCGCTGAAAGGTGGCGGCCCCATTGAAGCCGCTGTTCCTTGAGCCACCGCTGGACGAGGGCGATCCCGATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCGCTCTGCGAACAGCACGGTCGGAGAGGTGTGTTTGAATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCGTACGTCAGGACGTGGGCGGAGGCTCTCTTGCCCGACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCATCAGCTCGCGCCGATGCGCAACGAACAGCGACCGACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCTCTAAGGTCGTGTTCGATGCCGGAGCCTTGCTGGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGATGGCATGCGTAGGAGGGACGAAAAATCCCTGCATCCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGTAGGACGCCCGGATTACGCGGGCGAAGCCTTCGGACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCGGAGAGGGGAGCGCTGCGTAATGGCCCTGCCGCGCGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTGCAAGTTCGGGGAGCTCCCCGTGCGCCCTGTTTCCTTGAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTGCAAGTTCGGGGAGCTCCCCGTGCGCCCTGTTTCCTTGAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAGCTCTCCGCCGGTGAAAGGCGGCGGCCCCATTGAAGCACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTTCGATCTGCCGGAGAGCGTGTACGACGACGCGGTCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTTCGATCTGCCGGAGAGCGTGTACGACGACGCGGTCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCATACGGTCCGGGTCTTCAAGCTCTACGTTGTAGCAGGGCCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGCCAGCACGCCGCCCTGCCCATGACGCCCGAAGCCGTGGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCATCGCGCAGGCCGCGACGGGCGGCGCCGCCACGGCCCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCTCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCTCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTCCTATGAGGGAAGCGGCAATCGGGCCCGCTACGTGATAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCGTTGACATGTCGGTCGCGGCCGGCGTCGCCCAGCGATCTCTCCGCCGCTGAACGTACATTTCGCGCCTACGGG

>NC_021658|2|1|610407-614540|CRISPRCasFinder
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CCCTCGGGGTCGAGCCTGCCCCAGTGGCTCAGCACG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCCAGCACGCCGCCCTGCCCATGACGCCCGAAGCCGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCCGTGGCGCTCGCGCTTGCGGCGGCGCCGAACGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCGTCGATTCGCGGTCCAGGTCACGCCCGAGTTCCGGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	AAGTGCACGTATACTCTTCGCTGACTGGCTCACCCA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CAGATCGAGCCATCCGACCAGGAGGCGGGGGGATCCGAT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TAGACCTGGCGAACGTTGCCAGTGGCCTCGACGATCTT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCGTCGATTCGCGGTCCAGGTCACGCCCGAGTTCCGGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	AAGTCTCCGGTGTTAAACATCCGCTCCTCTGCCTCG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GACCACCGCGAGCACGCTTCCGCCGCCCGGAATCAC
CTCTCCGCCGCTGAAAGGTGGCGGCCCCATTGAAGC	CGCTGTTCCTTGAGCCACCGCTGGACGAGGGCGATCCCG
ATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGCTCTGCGAACAGCACGGTCGGAGAGGTGTGTTTGA
ATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGTACGTCAGGACGTGGGCGGAGGCTCTCTTGCCCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATCAGCTCGCGCCGATGCGCAACGAACAGCGACCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CTCTAAGGTCGTGTTCGATGCCGGAGCCTTGCTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GATGGCATGCGTAGGAGGGACGAAAAATCCCTGCATC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTAGGACGCCCGGATTACGCGGGCGAAGCCTTCGGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGAGAGGGGAGCGCTGCGTAATGGCCCTGCCGCGCG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TGCAAGTTCGGGGAGCTCCCCGTGCGCCCTGTTTCCTTGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TGCAAGTTCGGGGAGCTCCCCGTGCGCCCTGTTTCCTTGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGGTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTCGATCTGCCGGAGAGCGTGTACGACGACGCGGT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTCGATCTGCCGGAGAGCGTGTACGACGACGCGGT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATACGGTCCGGGTCTTCAAGCTCTACGTTGTAGCAGGGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCCAGCACGCCGCCCTGCCCATGACGCCCGAAGCCGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATCGCGCAGGCCGCGACGGGCGGCGCCGCCACGGCC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCCTATGAGGGAAGCGGCAATCGGGCCCGCTACGTGATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC

>NC_021658|2|2|610407-614614|CRT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CCCTCGGGGTCGAGCCTGCCCCAGTGGCTCAGCACG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGGCTAGATGACTCGGTCGTTTTCATGGTCCTGCC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCCAGCACGCCGCCCTGCCCATGACGCCCGAAGCCGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCCGTGGCGCTCGCGCTTGCGGCGGCGCCGAACGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCGTCGATTCGCGGTCCAGGTCACGCCCGAGTTCCGGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	AAGTGCACGTATACTCTTCGCTGACTGGCTCACCCA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CAGATCGAGCCATCCGACCAGGAGGCGGGGGGATCCGAT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TAGACCTGGCGAACGTTGCCAGTGGCCTCGACGATCTT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCGTCGATTCGCGGTCCAGGTCACGCCCGAGTTCCGGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	AAGTCTCCGGTGTTAAACATCCGCTCCTCTGCCTCG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GACCACCGCGAGCACGCTTCCGCCGCCCGGAATCAC
CTCTCCGCCGCTGAAAGGTGGCGGCCCCATTGAAGC	CGCTGTTCCTTGAGCCACCGCTGGACGAGGGCGATCCCG
ATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGCTCTGCGAACAGCACGGTCGGAGAGGTGTGTTTGA
ATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGTACGTCAGGACGTGGGCGGAGGCTCTCTTGCCCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATCAGCTCGCGCCGATGCGCAACGAACAGCGACCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CTCTAAGGTCGTGTTCGATGCCGGAGCCTTGCTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GATGGCATGCGTAGGAGGGACGAAAAATCCCTGCATC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTAGGACGCCCGGATTACGCGGGCGAAGCCTTCGGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGAGAGGGGAGCGCTGCGTAATGGCCCTGCCGCGCG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TGCAAGTTCGGGGAGCTCCCCGTGCGCCCTGTTTCCTTGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TGCAAGTTCGGGGAGCTCCCCGTGCGCCCTGTTTCCTTGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGGTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTCGATCTGCCGGAGAGCGTGTACGACGACGCGGT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTCGATCTGCCGGAGAGCGTGTACGACGACGCGGT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATACGGTCCGGGTCTTCAAGCTCTACGTTGTAGCAGGGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCCAGCACGCCGCCCTGCCCATGACGCCCGAAGCCGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATCGCGCAGGCCGCGACGGGCGGCGCCGCCACGGCC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCCTATGAGGGAAGCGGCAATCGGGCCCGCTACGTGATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGTTGACATGTCGGTCGCGGCCGGCGTCGCCCAGCGAT
CTCTCCGCCGCTGAACGTACATTTCGCGCCTACGGG

>NC_021658|2|1|610770-614540|PILER-CR
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCCGTGGCGCTCGCGCTTGCGGCGGCGCCGAACGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCGTCGATTCGCGGTCCAGGTCACGCCCGAGTTCCGGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	AAGTGCACGTATACTCTTCGCTGACTGGCTCACCCA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CAGATCGAGCCATCCGACCAGGAGGCGGGGGGATCCGAT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TAGACCTGGCGAACGTTGCCAGTGGCCTCGACGATCTT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCGTCGATTCGCGGTCCAGGTCACGCCCGAGTTCCGGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	AAGTCTCCGGTGTTAAACATCCGCTCCTCTGCCTCG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GACCACCGCGAGCACGCTTCCGCCGCCCGGAATCAC
CTCTCCGCCGCTGAAAGGTGGCGGCCCCATTGAAGC	CGCTGTTCCTTGAGCCACCGCTGGACGAGGGCGATCCCG
ATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGCTCTGCGAACAGCACGGTCGGAGAGGTGTGTTTGA
ATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGTACGTCAGGACGTGGGCGGAGGCTCTCTTGCCCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATCAGCTCGCGCCGATGCGCAACGAACAGCGACCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CTCTAAGGTCGTGTTCGATGCCGGAGCCTTGCTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GATGGCATGCGTAGGAGGGACGAAAAATCCCTGCATC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTAGGACGCCCGGATTACGCGGGCGAAGCCTTCGGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GAGCCTGACGACCAGGGCAACGGCGCCGGCTTCGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACGAGGTACGCGATCGACCGGTTCGCACAGCGCGTGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGAGAGGGGAGCGCTGCGTAATGGCCCTGCCGCGCG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TGCAAGTTCGGGGAGCTCCCCGTGCGCCCTGTTTCCTTGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TGCAAGTTCGGGGAGCTCCCCGTGCGCCCTGTTTCCTTGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGGTGAAAGGCGGCGGCCCCATTGAAGC	ACCTCGACGAACGCGTCGCGCGCGGACTCGCTGCGCAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GTCTTGCAGATGACCTCCCACGTGTCTGCGAGGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTCGATCTGCCGGAGAGCGTGTACGACGACGCGGT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTCGATCTGCCGGAGAGCGTGTACGACGACGCGGT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATACGGTCCGGGTCTTCAAGCTCTACGTTGTAGCAGGGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCCAGCACGCCGCCCTGCCCATGACGCCCGAAGCCGTGG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TTGAGATCGTCGACGTCGAGTGTAGGGAGCCAATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATCGCGCAGGCCGCGACGGGCGGCGCCGCCACGGCC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCCTATGAGGGAAGCGGCAATCGGGCCCGCTACGTGATAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGTACCTGGGCCCCAAGTTCGTGGAGCGCGTCCTCGA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020465165.1|619578_620664_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080681936.1|616042_616180_+|DUF3368-domain-containing-protein	unknown	unknown	gnl|CDD|378736
NC_021658.1|WP_020465163.1|614751_615693_-|IS1380-family-transposase	unknown	unknown	gnl|CDD|379340
NC_021658.1|WP_148313247.1|631648_632188_-|hypothetical-protein	unknown	unknown	gnl|CDD|237874
NC_021658.1|WP_020465154.1|598025_598988_-|hypothetical-protein	cas8u1	mkCas0114_cas8u1_CAS-I-U	unknown
NC_021658.1|WP_020465159.1|607554_607845_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
NC_021658.1|WP_020465158.1|605490_607494_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187766
NC_021658.1|WP_020465168.1|628206_629220_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381378
NC_021658.1|WP_020465155.1|598984_601984_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	gnl|CDD|274235
NC_021658.1|WP_148313246.1|616498_618202_+|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|224511
NC_021658.1|WP_044985453.1|618198_619404_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_148314691.1|596141_597131_-|radical-SAM-protein	unknown	unknown	gnl|CDD|234672
NC_021658.1|WP_148313245.1|607885_609076_-|hypothetical-protein	unknown	unknown	gnl|CDD|235562
NC_021658.1|WP_020465161.1|609171_609348_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080681937.1|623232_628152_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_021658.1|WP_020465166.1|620715_622275_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_021658.1|WP_020465157.1|603667_604945_-|type-I-U-CRISPR-associated-protein-Cas7	csb1gr7	pfam09617_csb1gr7_CAS-I-U	gnl|CDD|378223
NC_021658.1|WP_020465170.1|629696_630821_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020465153.1|597214_597961_-|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_021658.1|WP_020465156.1|601976_603668_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	gnl|CDD|274005

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_021658.1|WP_020465155.1|598984_601984_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	2e-136	450.6	5.0
NC_021658.1|WP_020465156.1|601976_603668_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	2.9e-90	298.3	24.7
NC_021658.1|WP_020465154.1|598025_598988_-|hypothetical-protein	cas8u1	mkCas0114_cas8u1_CAS-I-U	3.5e-96	316.9	0.0
NC_021658.1|WP_020465159.1|607554_607845_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	6.6e-21	69.2	0.0
NC_021658.1|WP_020465157.1|603667_604945_-|type-I-U-CRISPR-associated-protein-Cas7	csb1gr7	pfam09617_csb1gr7_CAS-I-U	3.6e-29	96.7	0.0
NC_021658.1|WP_020465158.1|605490_607494_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	3.8e-109	359.2	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_080681936.1|616042_616180_+|DUF3368-domain-containing-protein	gnl|CDD|378736	pfam11848, DUF3368, Domain of unknown function (DUF3368). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is about 50 amino acids in length.	7.22957e-06
NC_021658.1|WP_020465163.1|614751_615693_-|IS1380-family-transposase	gnl|CDD|379340	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	1.80719e-23
NC_021658.1|WP_148313247.1|631648_632188_-|hypothetical-protein	gnl|CDD|237874	PRK14971, PRK14971, DNA polymerase III subunit gamma/tau.	0.00210829
NC_021658.1|WP_020465159.1|607554_607845_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	1.05376e-18
NC_021658.1|WP_020465158.1|605490_607494_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.66928e-115
NC_021658.1|WP_020465168.1|628206_629220_-|aldo/keto-reductase	gnl|CDD|381378	cd19152, AKR_AKR15A, AKR15A family of aldo-keto reductase. The AKR15 family includes Microbacterium luteolum pyridoxal 4-dehydrogenase (PLD), Pseudomonas sp. D-threo-aldose 1-dehydrogenase (FDH), and similar proteins. PLD (EC1.1.1.107) catalyzes irreversible oxidation of pyridoxal. FDH(EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose. FDH (EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose.	1.57712e-142
NC_021658.1|WP_020465155.1|598984_601984_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|274235	TIGR02621, CRISPR-associated_helicase_Cas3, CRISPR-associated helicase Cas3, subtype Dpsyc. This model describes a CRISPR-associated putative DEAH-box helicase, or Cas3, of a subtype found in Actinomyces naeslundii MG1, Geobacter sulfurreducens PCA, Gemmata obscuriglobus UQM 2246, and Desulfotalea psychrophila. This protein includes both DEAH and HD motifs.	4.48593e-119
NC_021658.1|WP_044985453.1|618198_619404_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	4.04276e-07
NC_021658.1|WP_148314691.1|596141_597131_-|radical-SAM-protein	gnl|CDD|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	1.56015e-09
NC_021658.1|WP_148313245.1|607885_609076_-|hypothetical-protein	gnl|CDD|235562	PRK05687, fliH, flagellar assembly protein FliH.	0.00274593
NC_021658.1|WP_148313246.1|616498_618202_+|RNA-polymerase-sigma-factor	gnl|CDD|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	2.70267e-12
NC_021658.1|WP_080681937.1|623232_628152_+|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	2.53521e-153
NC_021658.1|WP_020465166.1|620715_622275_-|sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.04969e-44
NC_021658.1|WP_020465157.1|603667_604945_-|type-I-U-CRISPR-associated-protein-Cas7	gnl|CDD|378223	pfam09617, Cas_GSU0053, CRISPR-associated protein GSU0053 (Cas_GSU0053). This entry is found in CRISPR-associated (cas) proteins in the genomes of Geobacter sulfurreducens PCA and Desulfotalea psychrophila LSv54 (both Desulfobacterales from the Deltaproteobacteria), Gemmata obscuriglobus (a Planctomycete), and Actinomyces naeslundii MG1 (Actinobacteria).	5.49888e-59
NC_021658.1|WP_020465153.1|597214_597961_-|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	1.46818e-10
NC_021658.1|WP_020465156.1|601976_603668_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6	gnl|CDD|274005	TIGR02165, CRISPR-associated_protein_GSU0054_family, CRISPR-associated protein GSU0054/csb2, Dpsyc system. This model represents a CRISPR-associated protein from the Dpsyc subtype (a type I-C variant), named for Desulfotalea psychrophila LSv54. CRISPR systems confer resistance in prokaryotes to invasive DNA or RNA, including phage and plasmids. CRISPR-associated proteins typically are found near CRISPR repeats and other CRISPR-associated proteins, have low levels of sequence identify, have sequence relationships that suggest lateral transfer, and show some sequence similarity to DNA-active proteins such as helicases and repair proteins.	4.49392e-48

Protein sequences

>NC_021658.1|WP_020465161.1|609171_609348_+|hypothetical-protein
MLDFDHDVEVDRDVDVERRQLVHIAELAAFLRARTPVQAPEPGEGSHAGRADVRRHEL
>NC_021658.1|WP_148313245.1|607885_609076_-|hypothetical-protein
MSTRKRAFASAPRIAAKQSGDRNRGGGSPARNAGNTISAQPRRGARNTAAPAPLRTWRPAPSLRKNSTRCAEIGLPTRSTNPMLATASRRGRFDAFGKNVLRETLDLVGGADMQVEVIATSQTMDIWYVPDPARAALRAELGLLGELAAEPCQFEPFHDTPGPAELRDCVRKQLHWHHELERRAGGPVPFPRLCVLSSGRPATVLDAFGFDPVPGRPGLYRAAPGWRIDVVVIAELPRTRDTLLLRLLGARAVLRDAIRELIALPDDAWERGIALPWLLRLRFEVPADPSARTQEEAEEEEIVTEVQQWFEQLKQTLRDEARKEGLTEGRKEGLTEGQLRVLAAQFEKKLGRPLTEAEHPVLAERLDRLGSDRLDDVRLGLSADALTAWLADPAAR
>NC_021658.1|WP_020465159.1|607554_607845_+|CRISPR-associated-endonuclease-Cas2
MRQSYIVSYDVCDPKRLRKIFKAMRGYGDWLQLSVWQCELSRRELVELRRDLGQIIDAKVDQVLIIDIGPANGRGLSAIASLGRAYVPSERVAVVV
>NC_021658.1|WP_020465158.1|605490_607494_+|CRISPR-associated-endonuclease-Cas1
MARAPERVTDESSEPLIRAKPLPRRLPVAGTPPELVPARMINEVLYCERLLYLEWAQGEFEDNVFTVEGRSVHRRADVAGGELPPRPAGAAQGAGAEQAEVAASPAQPRRAPGRRADRDEEGDEPAPYEARSVWLSSERLGITAKIDVVEGDASGRLLPIEYKRGHAPDVPGGAYLPERAQLCAHVLLLREHGYSCDEAAVYFAASRRRVSIAIDDALIAATHAAAARAREVTRAAAIPPPLVDSPKCNGCSLVGICLPDETNLLRRLDGEDLDAAAASEGPPLEAGGSAELEGPLEVDPWGIAGAAAVDERVVEDSDDERGVELRRLHPARDDKVPVYVQEQGARIGLAGERLVIHTRTGGQTEARLSNTSQVALLGNVQISTQAMRALLERGIPLLLMTYGGYYLGRATGLESRNVELRVAQHRAAADEAFCLSFARGVVVSKIKNARTMLRRNHASPEAAVLSELDQLARKAAEAPSLPSLLGIEGTAARVYFGAFAGMLKAAGEVRGEFDLEGRNRRPPRDPVNALLSLAYALLAKELATTLGTVGLDPLLGFYHQPRFGRPALALDLMEEFRPIVADSVVVAAINNGVVAPDDFQRFGDAVALRPAGRKKFLLAYERRMDQLVTHPVFGYRISYRRVLEVQARLLARVLLGEVGAYPSFRTR
>NC_021658.1|WP_020465157.1|603667_604945_-|type-I-U-CRISPR-associated-protein-Cas7
MRSLDLDTLANAVAGGAAAIRAITRLEPAGGPGDKVFPPTYVKERNATTKYATEQRRIDGREVTTVLLDSVASQANRFEEALLDGFRRGELPFPIVQVDFSNEAGLADLEQITALQAPHRIADALLRDSVLGGTPFRHTAVGKEVTDARPTHATAMFKYCPTALIFGVWDSTGPKGGLGAKFQRCLVSEIVGIDIATGVKTASRLDPAGIQTKAGPVFKHKDPSQDWTVDPKEAELAKGGKPVEFSRSGGDGKKGSPSAINHGNIPPSIDAAAGGVTMSHAVQTTVLSLGALRRLRFQTACSGERLPTEQRDAAETAARTALAALGLAAVVYQRDQGYDLRSRSTLVAKEPLVFELVGRDGGEPERFSLSRAEAAALLKGAEQKARKLGLGWDAKPITLTPAPKLAGLIRKSRELAASGEAEDEG
>NC_021658.1|WP_020465156.1|601976_603668_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6
MLAIEVALLTGRYVATAVDDRDRAEWPPHPARLFSALVAAYFDTLDPSADERAALEWLEQQGPPEITAPEAAAREVVTVFVPVNDTSVVGSLDDEALTVREARAELDAARPAGGKPLAAAEKKLVKAEARFLEAVRKAIAPVPAGKEGKDGPVKATSILPERRTRQPRTFPSSAPAEMEPAMPRIVFAWPSATPTPEQRAALDALAARVTRLGHSSSLVTARVRDDRPEATWIPDDTGPGRAGDEAVLRVVGPGQLAALGAAFELQADTPGRVMPASFQRYVRPRAASEASAPAPLFGDGWIVLRRVAGPRLPSIRAVDVARTVRKAMMAAYGPGAPEILSGHRASGGPSERPHLAYVPLPFVGSEHADGALLGVALILPRDVTRDERLAIYRALDAWEQQARGGDEEPPRLPVHLGKAGELMLERLEEQTSATTLRPATWCAEAASWASATPVALDRNPGDLGARDPQKEAAAYAEAEATLAVACERIGLPRPSRVTVMPAAPLAGADKARRFPPFHAGKPPVQRVLVHATLTFDAPVRGPILLGAGRYFGLGLFRPLRANG
>NC_021658.1|WP_020465155.1|598984_601984_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3
MAELSPDDFAAYFEAIHGAAPFPWQARLLADVAREGGWPTLLDLPTGAGKTAAIDVALFHLALDAAAPPAQRTAPRRIVMVVDRRTVVDQAFERAKKIAETLTGAGNGVLRAVADRLRALAGLRGNEAPLALAQLRGGMPRDDAWARRPDQPLVAVSTVDQVGSRLLFRGYGVSDAMRPIHAGLLGNDTLLLLDEVHLSQPFRETLRSLCRYRTWTSRKLPDRWQVVEMSATPGSTAGTAGVTSAASDDGRVFGLNDDDRRDERLARRLQANKPAALAEVKVSGGEGARRAALAEACAEHALRFVAPGRAVGVIVNRVATAREAAEAIRKRSGGSVDPILVTGRMRPLDRDDLDERLGPLVRTGRARDAAADPVVIVATQCIEAGADFDLDAIVTECASIDALRQRFGRLNRIGAIEDARGVVLVRSDALAKDYVDPVYGNALAATWTWLGEATRDFGIQEMAAALPEGARLEAMLSQTSRAPVMLPAHLDAWVQTRPSPEVDPDVSLWLHGTDQEHAPEVQVVWRADVTGTLLAQAKRDEEAREALLKRVEACAPVGLEAISLPIHAVRAWLQGGAAPELADIEGRAMDDDEGDRHDGRLALLWKGDESRVIEPGELCPGSTLVVPGTYGGLAGGTWDPSSQVPVSDLGDRARWQQTGRPTLRLHPDVMRQHAGVTDAALPKIPVPVVDERSDAQDRAEIDAWLSEMSAATAATSWLGQVITALAVKGRRRPALVRLDGMELVGEDGAPRVEEGYFALVGRFRTRVEGAGDVTTEDDGASYTGVEVTLREHLGGVASWARRFAEQCGLPPEVARAVELAARWHDAGKVDPRFQRMLHGGSELRAAVAPEPLAKSALVAADRAARAHAIKRSGYPRGARHELSSVALLQGCERLFDKDVDRDLVLHLTASHHGWCRPFAPVVADDEPVELALEVEGTPVRVSSDHGLARLDAGIAERFWRLVQRYGWFGLAWLEALLRLADHRRSEEEQRGDIGARDDR
>NC_021658.1|WP_020465154.1|598025_598988_-|hypothetical-protein
MTELLLTGLDGKNPLAFLAALGVLNALADRTKDGTPEPRLVWRAGGTYQPAIMGGPDRGALLDVLVQDLASFRGEPAIEWLHYRKDGDGAEAHDLKPPPGFFVDYLSRLLGDCPSRGVSDELRRSLAFAAAFATDVAVDNNGNTKPTALHFTAGQQEFLTMVSELIQGVRVEDLEEALFGPWRYERPLPVLQWDNTSARDYALRASDPSKDKKLGVPGADWLAFRGLPFIRVAPVGDRIVTTGCSGEWKTGTFRWPIWTVPLSRPVIGSVLTSSEVFEVDPGVLRARGIAIVFESAIRRSDQGGYGSFAPARMARPARAG
>NC_021658.1|WP_020465153.1|597214_597961_-|radical-SAM-protein
MPTATRPQNATLTGALPLDRPTAERPHRLYVATTNHCNRACPWCCTCSSPRGRTFLALDRYRASFPPEGPFEVQLEGGEPTIHPHFDEMVRLARAEPRCARVVVVTNGVEIPRDPAALDAWLQKLGEPTTLKLSINHHLLEHDSGLLPLARAIHARLAALGGDRQLVLNVRLRKTEADGDAWVVEAVRDAGLLAIANVFHLQRYGFAQKREDWDEPFLVGTHFTMLNPDGRAFGPDLVARSDAMRGLP
>NC_021658.1|WP_148314691.1|596141_597131_-|radical-SAM-protein
MRFDLWGRPVEIYRNANFSIYSRQPCNAKCHFCVEELRPASRGRSLSLQKTVEDDDARYFDAMAESLDALRPLDPTVSITGGEPSHDPRLPRILALGQARRGRKRTLTTNGSGLLQRRDGKRVIDWIADTGVQHLNISRAHPDHDTNARLMVMKDGLSVDELRSVVSAAAAGGTRVRLSCVLLAGQIDSVDAIVSYLRFARSLGVDNVIFRQLMKTDPTAVVENHVVKYSDRSRVRLEPILDALSADARFSFERQIVGYYYYVEVFRFEDIDVVFEEADLAQLEETKRSGPGIVHELIFHPNARLASTWQPWDGILGPPPAARGSVDPS
>NC_021658.1|WP_020465163.1|614751_615693_-|IS1380-family-transposase
MLVDHGLALVARRKHRFVHIDVDTTVEPLFGMQEGALPGPNPRYHGRPSYHPILARVAEVDAIVGAKLRPGDTSFGEADVPFVEECIDRARAAAPSAVIYVRIDGAGDCSALMHAVAMKGCFFLTKARMSPDLVGMVAHATGWRTIDWDADGRPRRQVAEVPFRCSDWPDSVRVIAVRTRDRENGKQIYLWEGLDYTVQVFLTNEPVEAPEDVAARYDLRAGIEPLIGDLKHGWGCGRVPSHSFNANHAALLLKLLTANLMRRYVLDHVPHLASWRTPWLRRALILVPGRLARSARGTKLHVPERSQLARWLN
>NC_021658.1|WP_080681936.1|616042_616180_+|DUF3368-domain-containing-protein
MGLLVEARRAGVLGSLRAVLDDLANAGFRVSALLVTEALRQVGEE
>NC_021658.1|WP_148313246.1|616498_618202_+|RNA-polymerase-sigma-factor
MSPLSPPPPPPPPALPPPPPDLVQHSTWASMHATAVHVLPGMLRYLGVAQGDIDDLSQEVLLGAYISLPRYDPHYPAGAYGAPFPPPSSASPLHDLVFAAVPVSIAAAAAAAAADPADPSEPAYDPASPPLRFPPALSSRSRPAHLGPRWRSESAWLFGIAWRKVRSHLERAYRRREVPVGLADAACFEGAEVAPSSEQRVVRKERIALAIRLLASIAPERRAVLLMADAYEIPMREVARALEINENTAASRLRLAREDYRAAVKRLRAEEQHALRSRLLMLPLFSLASASSASSAAPARAVLAGASAIAEANAPATLPSPRSDPGRHDPADRPRNPARSARFARVAHLARPLARFVRPALARGTAAIVGAAVVVAALAPAPVSWANRLAPIATQLVAARAAHAGARPETDPGEPPRSKAPPRDALAAIPAKETSAVRTPPPALPPPAPADGSGHLKPAAPRQHASSERRQDPLTEEILLLEAVRQALVQGDRATAMERIAAHERRFPQGRLKLMRERLRAKMDPAQPAPAGNPTQPAPAGNPTQAAPAGNPTHPVPAGNASREMLP
>NC_021658.1|WP_044985453.1|618198_619404_+|hypothetical-protein
MTARTRRARRTPRGQSAITNAIATWFQRAALAAMTAAAIAILGIAPVRAEPRATPTRVRLEFLRGPGAEECPDERFLREQTIRRLAGVDPFDAAAPLTLTASIERQRGELAAALFLRDRSGRGLWADGFSARVDCEVLVSAIALSIAVLLDGDELPAMSGATPDLPAAPGAPPAPPQPTDKAMVPGPPCSPDRPCPPQPAPAPVSPSQKTPPPRKTPPPRKTPPGSSAPPAPSERFRWVAGLDAVAGLGLTPGVSLGSAMSIGARWPAWSAALEVRGLSSLPGKIDAVDMSVSTITANIVPCLNRRTVFACGLAELGVVRTAPSTPFDVASRLRFRAGLGARAGIAWPLAENLSMRAHAEIVHPVIGAALLRHPGVPVRERPMWSALALGAALGIGLQVSL
>NC_021658.1|WP_020465165.1|619578_620664_+|hypothetical-protein
MLLIAGCELEPVIITGPCTQEEIDLGYCDVPDAGTTSTGGDGGDAGAGGQGGAGGDTHSSLCSGQCAPPAPLGWFGPALLWFGPSEAVPDCPADAPTLGYEGFADLQQPPLECATCACDPPDASCSLPTDWAAASSSSCPGDEPGTVTTSFAAPDGWDGACTAANAIPADHLCNGEPCVQSLTIAAPSVVTTGACTPREDVPPPIPRLDPWATRARACLAGAYTACDDATTCVPSAPSGFTTCVFHEGDDADCPDGYAVRHLFFADVIDGRDCTPCGCGDPTGASCTLMASVYRDAACTDLLASNVVSSSVPFCVVTPPGVALGSKSAVIATVEPGRCAPHGGEPVGELRPSAPSTFCCIA
>NC_021658.1|WP_020465166.1|620715_622275_-|sensor-histidine-kinase
MDDAGPPLTSSLAARLRSCKRAVIERWTRRVLDDPRAMAKQHGGPLLADEVPRLFDDLIEALAASRRAELRAGEDGEPASAHERIEDQARLHAAQVRCIAATLRELSHLRAALIEVCAAQGICLGVREAQVLHAVVDASMWTSAREIETATRAALEDSAARLRLATEAGGVGVWDYDTVTGALRWDDRCRQVSGVGPEQDVDYELFVSAIHPDDRARVQEAVLRSQDPASGGEYNIEYRLVGLRDGIERWVCVQGRACFDAAGRSVRMIGTVIDISERKRAEAARREELAFRDRFLGALGHYLRTPLTSVTLATSVLMHHGNLTPGQAKSVERIAASARRMGRTIEDLLDLTRSRFGGSIPIAPSPGDLHLICKGAIDELGAMHAGVPIRLDLHGSGAGQWDPERVAQMVTNLVQNAVDYAAPGSAVRVAIRPRGDDVLIEVHNDGPAIAPELLATLFDPFHQAMVGGRTSSGRGLGLGLFIAHQIARAHGGGIEVESEAERGTTFTARLARGAAEARC
>NC_021658.1|WP_080681937.1|623232_628152_+|AAA-family-ATPase
MTTRRPGVERGTARINGYQITAKMGETAASVTYRARREGDGREVAVRMLHADLSRIADVTRFKHACSAIRRIDSERIVKVHGVEEHADGLLLVTEYFPGAALSELLKDRGELDVGGFLSGAIRMTEAVADIHRRGLLHGDIRPRNILLGEGGQIKLTGFGVESIVTREREAIYGREVLSEVLPYTSPEQTGRMNRSVDYRADLYSLGVVFYEILVGRRPFEAADPLELIHAHIAVKPTPPSELNPKVPPALSAITMKLLGKNAEDRYQSTEGLKDDLEECRRRWEERGAIDDFTPGQHDRTDLFQIHQKLYGREGDIRRLIESFDDVLRGRRAIVLVSGYSGIGKSSLVQEILKPLARERGYYVSGKFDQYNRDTPYSAVVHAFDALVKQLLSESEERVQRWRRAILDALGSNAQVICDVLPSLGHLIGAQPAVPALGPVEAQNRLNLYFKKFVAVFARPAHPLAVFIDDLQWVDSASLSLLKSLLADEGMESLFFCGAYRDNEVSPTHPFLVALEELQAARLGVVDIVLEPLRLAHLSELLSDSLRTGGTDALARAVLKKTGGNPFFVKQFLRHLVEVRALVLDPAAGWRWDLSTIKELEHTDNVLSLMAQTIRRLPEDTQEVLRLAAAIGNSFALEILNTVSAEAPDATYGSLARAIDDGLIVSAGEGYRFAHDKIQEAAYSLIPARDRPGFHHRIGRLLLGKLDPDDGQSVFEVVNHLNSAGDLIQAPEERLTSARLNLRAAARAEESSAFSASLKYLEHGISLLPADAWTSEYELTFAYHTKKGVLESLCERHDDALATLSGCLDKARGRVHETEVRRLKINVQILKNDLPAALDEGLAALRAFGIDLPPYPDDALLTAEIERTMALIGDRPIASLIDLPALADPEIAALQDLLQEMFSPTYQLGTNNFGITVMKMLQNTLTHGISRNSIYAYVNFGTILCARLDVERGYEFGRAAVRLNELNPDKKSEAMLCNMWGAWVQHWRESYATYKASLRKGMHVGLETGQYIWAFYNACNSQLSSLLLGKNLHELVQEAKDSEHICKLDRFNAITWIVAAAADLGEELSTPAEGDGDRPRARRVDLDAIIAEARRINNTASLYFTNIFTVIGGVFKGEHERVAAVWGETDPGADVMLGAWHASPCYYFYGGVASSRASTAAAPALGSAYVERLRAFAGKLDLWAGLNPQIFLHRSLILRAELARIERREGAGALYDQAITAAREARLLHDEALANELCALHYRDMGREFLAHAYIAEAHRLYARWGAARVTERLERDFPQALGREAPRQAGAGDHAGAAQRASLDHAAEADHGKAKLDTLAVIKASQAISGEILFPSLLKKLMQSILESAGARKGLVILRDNDRLVVQAEGHVEAREIKVLSPVPLEACGDVAASVVHYVTRTAESVVLGDAASSDLFASDPYIARTQARSILAAPILRQGRLVGVIYLENDLAAGAFTPDRLEVTRLLAAQVAISMENALLYASLEEKVRTRTAELEVAHERIEIELSEKLALIARQRELIRTLSTPILEVWDGVLTIPVVGGLDDDRASTIMQDLLERVVDTQSRSTIIDLTGVSAIDPGSAERLVRIIRSVQLLGSRSIITGIQPQVARTMISHGLDLSRVTTRAKLRDGLRMCMG
>NC_021658.1|WP_020465168.1|628206_629220_-|aldo/keto-reductase
MKLKDILPGKLGFGTAPLGNMFRDIPEAEARATVDAAWDDGIRYFDNAPFYGAGLAEIRMGEALAGRPRQDYVISTKVGRVVLDQVEDVSARDLGEKGGVFKHGRPNKVVNDYSADATSRSIEGSLERLKTDHIEIVWVHDVAQDFYGDEWLGVFESARKGAFRALDRLRDEGVIKAWGLGVNRVEPIELLLALEEPRPDGFLLAGRYSLLDHERALQRVMPEVAARGLGIVVGGPYSSGALVGGPNFEYAPATPEILDKVARIKTIADRHGVSMKAAGLQFALAHPAVAAVIPGASRPGRIAEDRAALNEVVPADFWRELRRADLVSPAAPLPIAD
>NC_021658.1|WP_020465170.1|629696_630821_+|hypothetical-protein
MGGADDVSTHGAGDNSAAILGGTVDAPVDDDGAPPWARPPTREEAEAILERVVALYQDHAAAANPAGTHEISWRIDWDSDAVSAHVLLNRGEDWTIEVSKGWLTASSMTAEVFALTMCHEMGHFIGGFPFKTSGRGDSTGALGTSVAAEGQADYFATKDCLPRLRANETEANAAAFAELDPSARERCTTAYGDLASQQLCGRILRASLQTGRLYEEQEVLQAPRELVYPRFDTPDTTEVAVTKEGHPTSQCRLDTLVAGAVCSVKATGTEIPGFVPPYGEYSDASEEAARPFACQTGPGARPRCWFQPDTVATDCSELGEQACVVEEGRTGVRYCDTTFGVTYYWCFGDEVCKTSRDGFSDCYAPDVDPDEGSF
>NC_021658.1|WP_148313247.1|631648_632188_-|hypothetical-protein
MAAGAMLEGGATGSACGGRTGAWATGEEDGGPAGESPAASVVIAAGSKPSAMTSAAAPASASHVGAPSARSPAPSGLSVRSVSEKPPSPVRVTCALATSRCLPFVRGFPPRRRSISWSTAALEGHVSGACHESEIGCSCAAAVRTVSATQRKEAAVRTRRQRIMNAKPHTSANRGHLVG

Crispr_ID: NC_021658_3

• CRISPR_ID: NC_021658_3
• CRISPR_location: 675300-675412
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_3

Consensus_repeat	Method
CCCTGAGCCCCGCGGGCGGGAGGGCCG	CRISPRCasFinder

spacers of NC_021658_3

>3.1|675327|59|NC_021658|CRISPRCasFinder
AGATGCTCGCGACGATCCCTGAGCCCCGCGGGCGGGAGGGCCGCAATGCTCGCAATGAC

CRISPR arrays and Neighbor proteins around NC_021658_3

CRISPR arrays

The CRISPR arrays of NC_021658_3

>merge|NC_021658|3|675300-675412|CRISPRCasFinder
CCCCGCGACCCGCGGGCGGGAGGGCCGAGATGCTCGCGACGATCCCTGAGCCCCGCGGGCGGGAGGGCCGCAATGCTCGCAATGACCCTTGAGCCCCGCGGGTGAGAGGGCCG

>NC_021658|3|2|675300-675412|CRISPRCasFinder
CCCCGCGACCCGCGGGCGGGAGGGCCG	AGATGCTCGCGACGATCCCTGAGCCCCGCGGGCGGGAGGGCCGCAATGCTCGCAATGAC
CCTTGAGCCCCGCGGGTGAGAGGGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020732503.1|673942_675106_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|366166
NC_021658.1|WP_187345851.1|664262_667283_-|hypothetical-protein	unknown	unknown	gnl|CDD|225750
NC_021658.1|WP_020732504.1|675729_676950_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|234945
NC_021658.1|WP_020732507.1|682277_683171_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020732506.1|681540_682239_-|thioredoxin-family-protein	unknown	unknown	gnl|CDD|239267
NC_021658.1|WP_148314692.1|659028_659313_+|hypothetical-protein	unknown	unknown	gnl|CDD|184918
NC_021658.1|WP_044987418.1|677675_680813_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020732512.1|686460_688782_-|DUF4139-domain-containing-protein	unknown	unknown	gnl|CDD|379285
NC_021658.1|WP_148313256.1|672574_673528_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044985457.1|676963_677488_+|J-domain-containing-protein	unknown	unknown	gnl|CDD|197617
NC_021658.1|WP_020732510.1|684213_684570_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|369571
NC_021658.1|WP_148313257.1|683173_683941_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239488
NC_021658.1|WP_020465197.1|659309_660644_+|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|212030
NC_021658.1|WP_187345852.1|667305_667659_-|hypothetical-protein	unknown	unknown	gnl|CDD|240291
NC_021658.1|WP_020732511.1|684683_686441_-|DUF4139-domain-containing-protein	unknown	unknown	gnl|CDD|379285
NC_021658.1|WP_020732509.1|683921_684179_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020465195.1|658180_658699_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020465198.1|660991_662644_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_021658.1|WP_020465200.1|667804_672562_-|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225114
NC_021658.1|WP_148313255.1|662664_663168_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020732503.1|673942_675106_+|alpha/beta-fold-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	4.14261e-21
NC_021658.1|WP_187345851.1|664262_667283_-|hypothetical-protein	gnl|CDD|225750	COG3209, RhsA, Rhs family protein [Cell envelope biogenesis, outer membrane].	1.32893e-26
NC_021658.1|WP_020732504.1|675729_676950_+|GNAT-family-N-acetyltransferase	gnl|CDD|234945	PRK01346, PRK01346, enhanced intracellular survival protein Eis.	1.66304e-125
NC_021658.1|WP_020732511.1|684683_686441_-|DUF4139-domain-containing-protein	gnl|CDD|379285	pfam13598, DUF4139, Domain of unknown function (DUF4139). This family is usually found at the C-terminus of proteins.	2.4315e-56
NC_021658.1|WP_148314692.1|659028_659313_+|hypothetical-protein	gnl|CDD|184918	PRK14954, PRK14954, DNA polymerase III subunits gamma and tau; Provisional.	0.0049539
NC_021658.1|WP_044987418.1|677675_680813_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.64249e-87
NC_021658.1|WP_044985457.1|676963_677488_+|J-domain-containing-protein	gnl|CDD|197617	smart00271, DnaJ, DnaJ molecular chaperone homology domain.	1.1622e-10
NC_021658.1|WP_148313257.1|683173_683941_-|phosphatase-PAP2-family-protein	gnl|CDD|239488	cd03394, PAP2_like_5, PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	7.38817e-11
NC_021658.1|WP_020465197.1|659309_660644_+|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	2.06316e-09
NC_021658.1|WP_187345852.1|667305_667659_-|hypothetical-protein	gnl|CDD|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.000280378
NC_021658.1|WP_020732512.1|686460_688782_-|DUF4139-domain-containing-protein	gnl|CDD|379285	pfam13598, DUF4139, Domain of unknown function (DUF4139). This family is usually found at the C-terminus of proteins.	8.47222e-34
NC_021658.1|WP_020732506.1|681540_682239_-|thioredoxin-family-protein	gnl|CDD|239267	cd02969, PRX_like1, Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic cysteine found in PRXs, which aligns to the second cysteine in the CXXC motif of TRX. In addition, these proteins do not contain the other two conserved residues of the catalytic triad of PRX. PRXs confer a protective antioxidant role in cells through their peroxidase activity in which hydrogen peroxide, peroxynitrate, and organic hydroperoxides are reduced and detoxified using reducing equivalents derived from either thioredoxin, glutathione, trypanothione and AhpF.	4.80348e-54
NC_021658.1|WP_020465198.1|660991_662644_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	8.04877e-05
NC_021658.1|WP_020465200.1|667804_672562_-|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	6.16501e-121
NC_021658.1|WP_020732510.1|684213_684570_-|cupin-domain-containing-protein	gnl|CDD|369571	pfam07883, Cupin_2, Cupin domain. This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel).	1.31747e-15

Protein sequences

>NC_021658.1|WP_020732503.1|673942_675106_+|alpha/beta-fold-hydrolase
MILHQSQVEQTVDRDERDRFIKELVVVRVRSTAVEVAPASRGIEGARAPGGEDPAVDRETVAHDVPLAMIRKRSARLRSTVASVLLIHGYGQNRYIWHLPSRSFSNYLARAGFDVFNLDLRGHGRSRHLGARRPGHVTDFVREDVPAAIEEVRRISGPRPVYLVGHSLGGLISYATAPTMGDAVGGIITLGSPYLFTHGSRVLELVGRLMLTVDQRVPLGQGALPLSAWGEPFRFVRAFIESPIFPLPIRGFVPGSMETRVLTQHMSLAMDSGSITVLRNMFLDAAASRKSGQHMGSLFGYAKAFEGLDLPLLVVAGTLDDLAPPASVKPAYDFSRSSDKTYREFPRGHLDIVVGRDAPLTVWPLIEAWLKTRVRRAAARERERLSA
>NC_021658.1|WP_148313256.1|672574_673528_-|hypothetical-protein
MYHLKMGRQLAVGVPARAAALAALLGAVCFAGTARAQSKDGGGSAPDDAVAADEQAKDEQAKDEQAKDDKAPAGKDELPEAPPEAADDNSPFEKDGKAHKFIGLRLRNVIVPKFMINLFADGGATVNVFMIGPEFTSRKNGLEIDLALSYADYSMDPFLFKGKNDDQFAWEMVSSDMKLLYFTSDLLFDVPIDDKGRFSLLVGGGVGIGLVFGDLHRAQAYPGAAGSNPSPDDVSAWRKCSGLGGPGGAYCDGSNNHYGDYSEPSWVNGGSKPSVFPWISFPQVSFRYKPIKQLQTRLDAGFSITGFFFGLSAGYGL
>NC_021658.1|WP_020465200.1|667804_672562_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MTSHPLFPPRYEPIGTLGKGGGGEVWAVRDRITGKTVALKTLGEDADEPEVLALVREAAALSGVEGLGVPRVLRFGRLPASGRPFMVRELVEGTSLADLLARKGDLARNLAAIADAADQLTRLHRALLLHGDVKPANIIVGEGGRATLVDLGLATPFRDDGSRPVGLTPRYAAPELFKGDPLTVRAEVFALGATLAEALRQSEGEGARDPKVIGALQEVVDRATAREPNARYPSADELANALRRAARLPCGPSEEPAGPAEPGARPDAGAGAVVWPIVGLDAPSGRLLAQIMALPAGSGLSIAGPPASGRSALLRRIAWSLEVGGYAVAWVEAARVADPREALAIELSAHDPGRVTALVDDADRLGDAEIERLDEVRRAGGKLVLVLGDPRERGAGGADGAPAAGAPSPGRAAAFARGFQRFEMAPLDEQVARELVQRTIPSLSDAVAAHVVARAGRWPGRIREIVARIARAPVASTEDVDRLLEAPPASGAAASGPGGAGAEGAALPPAEIHRLLDRGHFDAAAEALGRLQGDGSPVVVPVVVIARARLAMNRGDTARALAELARAKDQVEASGDRAQAAFWSLQMARALLRTGDYGEAERRAGEAVERLGPLKLEAELPGEPRPELATAAAFGASPEAIVAEAVATRGLAQSFASRHEDAKRTLEHAVRLARLTGEPRILSVALVSLAFALQRDDRLSEAKAVYEEALTAAEQAGDAGTLATTRLNLAALTKLQGDLGAAIRHLEAAVDLGRRSGRVTTIRQALLNLANLDLYLGRLARARVSLDALAAQRADLAQQQHAQLLALEAEHAARSGDLEQAERLCLECAEAYEAMGRRIDGVEARLERVLFAVARAGADPRALGEEIDVAAERLGTTGAHRALLALARGRVAALARDERRARAAYDEALEAARAAGQRDWIWRALEARAQLETERGHLIRARHDREEALITLEEIASKLPRDLREVFWNDARRKEIRAAAMLELMSSRTVPFAQPGAGPAPGAGSTQGAASQAAAAPPPGEDRLARVLEINREIAGEHDLTRLLAKVTDHAIALLQAERGFIILQRPPRGEPPPAAGEGAVDLSIHASRDQAGDDPHARFSSSIAERVISTGEPVVTASARDDARMSDYVSVHQLMLQSVACVPIRQRSGQVIGALYLETRLSAAAKFEAELPTLTALADQVAIAIETARLVGENERRARELERANEELRAARAKLEELLGHRTAQLAATRRDLRSARAVIRGHFGYEGLVGTSEAMRRVYALIDRVKDTDIPILITGESGTGKEVVARTIHNASPRAKKPFVGVNCGAIPEHLLESELFGHVRGAFTGADRDRKGLFREVTGGTILLDEIGEMPQKMQAGLLRVLQEKVVRPVGGAREEPVDARVIAATHRDLADMVSRGTFREDLYYRLHVVEVRVPSLRQRIEDIPLLIDYFLGIFAARYGRDRRSVSRAALKRLSAYSWPGNVRQLENVLLNAWVLSDRPELESDDFELPDAAPRSLRGAEAPPPTRAPLGGGGAPASAGRAPPSSEPLRVETSLDAHKASERERILVALSSCNWNRVKAAQVVGLPRRTFYRRLKEYGIQ
>NC_021658.1|WP_187345852.1|667305_667659_-|hypothetical-protein
MSDRSNLAASIDGAPLPDEEARDLWTRFSRYMDEHRGDMAGFARENGYVSVTPTFDRGRALLVVRTTEAPPEKPAPRGGGGGEPGPRGGGKPGPRGGGRPGPRGGGGKPAPRGRRRR
>NC_021658.1|WP_187345851.1|664262_667283_-|hypothetical-protein
MRCVESRLDPGESARLPCGVLTRYPWGYALAAGGLAYLLAEARGGRWLLSRIVDLHDNLIELSYEDGRLAHVIDSVGRVVRARRHKDGRIAAFEVKNATAQGRWEARRRYAFDARGDLVAAEDAAGHAHRFAYDEDHRLLRREEPGGLVAEFRYKDGRCVEAWCHRDGNDALANRVRVVEPDGAERRIRYDFLGRVVGFTDEAGHETRYAYDACGRLCAVFGPGGAVTRHDFDADGNLAKITDADGRTTTLRWGGFHVVTELVRPDGTRVLYRYDREQDLVRIVNEAGDEHRIQRDGEGRITGERTFDGREIAYRLDLQGRIAQMRCGPATVDFEYDAVGRLVKRATSDGREDVFDYDPLGRLERAASGDVECVYSYDRRGRVLTEVTRRGGEELAAFAWTYDAMGKAIGVRGPGGEVAVQRDVVGRPVAALVGDEREPLRLAYDARGFEVERVLPGGGTIATEVNADRLLARQSVLGKPATPRIRPGEPPWVGPLVAPATWRRTYAWSPAGLLRAAQDRGGATGEMLRDANGRVIERRRAGKAAERFRFTAAGDLERADERRTYAPGGRLTARAAGREIVRYEHGERGDVVRKRVTGSGAAGEQERERVWAYAWSGDGRLMEARTPEGRTIAFAYDAFGRRIEKRVARMGEVESVTRYAWRGGALVHERRERADGAGARIVEERSYVTLPESALPLAQRDGAAGALRYFVHGVNGFPEALVEGDGSVAAELGAGLYGEVPAEHAALTPLRFPGQYADEETGLYYNGHRYYDPETGTYLSPEPIGLEGSLKAYAYVDNWPTELVDPDALAKMHTEVAGTYTGKNGKAGSLTREAHSGQAQRERLHPAVQAALPPTPARPPGSAGNPEDCSEPKALSDYLNRWEEKTGKSCHPDDPNWQNHLQEALGGIESIKSYKGSNKDSLEQACPNCTQTIARLWSLAGLPPPGSKVPGGGTRFAPADPKWNPAWSPGKSDAQSPTTKGTYKDKDGNVVQPGAWHHDGSGWVKL
>NC_021658.1|WP_148313255.1|662664_663168_-|hypothetical-protein
MVFWGSAAGVWTYAYLPERMSFEAGEVLTWLETLAFEEQLEESGQLREEFAFPLRSRRYADALVRQLHLRRMDECSDHRVTSYVGDGLWLRQLSPPFGRSFLVLRSDSVARAVDIINGAKEYIAKPPTISVSNWSPNRESLIEALRTYGIRTATSARLWWSDFRHVK
>NC_021658.1|WP_020465198.1|660991_662644_+|tetratricopeptide-repeat-protein
MRRRAEAQSELKGVDGEPATQRSFESASDRCAPKSGSLSEVLGDGAMRGPRSSGAPPSLAGTAPEARGHALRERGNLLLRRNDYASAARDYDEALALFQAAGDGLGQAQVLMDRGALRLREGVPVQAVRDYDEALALFQAAGDRAGEGEALRARGFARAEEGDLGGAVCDYDLAIQLFLQLGDREPLKPRAGSRAAAPDADGAGPTESPRARPHGAAHARALKSRGDLRVRLRNLPGAARDYSTALALFQGAGDRSGQASVLKARGDMRLGQDNMTGAARDYDWALTLYQATEDHLGHAGVLKARGDLRTRQEDLAGAERDYDQALELFTATRDVLGQAAVLKARGDMRSLQEDLVDAVRDYDRALALFRTGFERRGQAATLKARGDLRRKQFELVAELVGVAAADASDLEDALSDYEQALALFEVLEDGAGQAGVLRARGDLSRIQGDLGAALELYLSAKRLLDVSGNAAELSATLAEIARTHALAGRASEARAAAEQALARADRATSPEVRELAEAVLSGRIAARPEEGAARDSRVPISPGRFERERF
>NC_021658.1|WP_020465197.1|659309_660644_+|LysM-peptidoglycan-binding-domain-containing-protein
MKFHAKATLVPVSLALAAAAPLALAQEQGGEEGAGQGPGVTVVQLPPAQPTVETQVVVPGYPQPGFDPNAHLPSSSRGTTDTSRASDGFDLGRRSEGPASVRGGANGSYVVEGQFVPESHSVRRGDTLWDISGRYYTNPYAWPQVWALNPQLQNPHWIYPGDRIRLRDPNEAPTRGNIGLGLTKGGRGGRVPAKTIFLRDLGWVDDVKKDTWGELVASPDDQMLLSEGDDVYLRLSGDHEVAIGQELTIFREIKKVRSGGDDKGELVTVRGTARVDRYNPKTHMVRARLIESLDVVERGDRVGSVARRFDVVPPASADADLEARIIAAIYPYQLFGQHQVVFIDKGEKDGVKPGQRFFAVRRGDRWVQQLGGAGKLATLRPRVQDERPAQVDAPKFGVDEELLPDETYAELRVLNVRERTAAALVTSAMYEVERDAVLVSRKGL
>NC_021658.1|WP_148314692.1|659028_659313_+|hypothetical-protein
MRADSAVLADRLGSLERARVAPRVAARPDEAEPRAASPEELDRPDLEVVRLAPEDDGARPPALRSTANGVVIDEPPGGSPPPSPPPSTPSRRKR
>NC_021658.1|WP_020465195.1|658180_658699_-|hypothetical-protein
MNVRKFFLIFVIATTGAACGGDDGPGPAETACFDYSKFDGATPEVSFATDVLPVFQRSCSFSSTCHGAEAGSAGFAYLGPAVSEQATPAQIDAIVAQNVGVPSRAPSGMPRIAAGDPANSFLMHKLDDTLSCGDLECTPDQCGAPMPYTGDTLPAAERDAVRRWIQQGAKVN
>NC_021658.1|WP_020732504.1|675729_676950_+|GNAT-family-N-acetyltransferase
MDIELRQMAADQHAEFRQPILTAFGMPTTPERLEGMKRLPELTSRIGAYEGASVVGAAGSFSFSMTSPGGVVPVAGLTMVAVNPTHRRRGILTRLIRRHLDDARAEGRPISSLWATEGGIYGRFGYGIASQACSISIERDRAAFRHEAGAEGRARLLDEAAALEAFAPVWERARAFAPGMLARSKVWWQVRRLADNDYTRQGGGPLQRVVIEVDGRAEAYALYCMHHKWDASSIPVGSIRVIEAIGATPLGTRLVWRYLFDIDLAQRIEASLLPPDHPLGLLLVEPRRLRLTASDGIWVRIVDVEAALAARAYGSAEALTLEIVDRDCPWNAGRFRLDGGERRAARTSAAPDLRLDVAALGSAYLGGVSFRCLADAGQVEQLSEGAVERADRLFRAARAPWCPEIF
>NC_021658.1|WP_044985457.1|676963_677488_+|J-domain-containing-protein
MTLPLRGVYAVTPTRRRRFLWAAWWTAEPAREPFRPPDASQGGARTVEEARAQAERAAGRPLVEIEPAWATAWTRILRGEPPWPKPRGRREAPPPPAAEPSGRAPSRPASARGVSPFAVLGLPEAAGAAEVRRAFRRLALVTHPDRGGDAGEFMRVKWAHDEAMSRLTRPKRRA
>NC_021658.1|WP_044987418.1|677675_680813_-|protein-kinase
MPSRFPIRDWDRYECVSLIGRGGMGTVYKAKDPRLQRYVALKLIRGNDPDLAQRFIWEAQAQARVEHPNVCKVYEVGEAQGQPFIAMQYIDGLPLHRVAQQTSLEQRVKIVADVADGLHAAHRLGLIHRDIKPANILVERTADGAFRPYLLDFGLARDIAADGRATTSGEGTPAYMAPEQVSGGQRQLDRRTDVYALGATLYEILAGRPPFVDPSVTSLVARVANEPPVPVRQIDRRIPLDLETIVMKCLEKEPQRRYDSAKMLALDLGRYLEGEPIDARPASLAYRALKRAQKHKLAVAAAAAALLVLALSGAVALRAKLAAARQAERSAHMASLAQGFGQDVKEMELFMRYAYALPLHEVSREKEVIRARMGEIDRKMQAMRDAGGDLVEGPGHYALGRGHLALHEPEEALSHLEAALASGYAAREAKFAAGLVHGMLYRKGLDRARRLADKGERSAHRLELEERHRLPALKHLRDSARAAAEPSSYTAALIELYEGRFDEALADARRAFARSPWEYEAKMLEGDILLAKGAAARDLGEPEAALAEFRDAVASYEVAAEMAESDPDVHEAAARALSEIMLIEAQRGGGADELFAQIIARCDKALRANPRASGAHAKKAWALVHRARRDLARGADPRPDLVQAIAESEQAVLGDPSDATAHGAMGASIFLLASHESSLGLDVRPSLGRAVESMERSLALDPSSFWAWNDAGIAYGMMAEDSASRGADPLPLFELSASHTARAIEIAPNDAPLHLNQGWFYAQRAQYELDHGTPPDESLELAKDNLEAALRLRPDSRPAHGALALAYLIQGRYERLAGESPEVSLARSLDGYGAAMRLRPGDLEAQQGAGLARLEAARWALDRGEDPAAALRAARGAVERVLSARPASPGALLALGQVDLLAARWFASGGRSPAPPLDAAERALLRALESSDRNARIVGALAEVHRLRATSAAPSLVDARAEVEAGLAMIDRALAIDPALPAASAEQGALLLLKAKAEPDPAQRRELSLRAASALERALRKNPLLGREYAPLLDEAGKVAEAVKR
>NC_021658.1|WP_020732506.1|681540_682239_-|thioredoxin-family-protein
MHKLIPLTFLAAALAACTQPGEPSAPAANGAAAAQPAKPAEAKPAEAKAAQAPATQAKIGQPAPDFTLPDLDGKPVKLADYKGKTVVLEWFNPGCPFVQLAHRKGGLKGVPAQHTQKGVVWLAINSGAPGKQGTTREENVKAKQEFGMSYPLLIDEKGDVGRAYGAQRTPHMYVIDPQGTLVYAGAIDSTKGGEPEPDEQVTNYVDAALAELTAGKPVSTKETEAFGCTVKY
>NC_021658.1|WP_020732507.1|682277_683171_-|hypothetical-protein
MALRRTPAAAAALAALALAPAAARAQDPADLPPPAADAPPVSSGVDLLQKRSYWARSAGARPFVSAVLELGVIYYRPSLALGFGKPHWSWLGIEGYASVSPSGGAEYVGLRAALPGVEIRGGARYAFSTSQYFLEPRASYTRRETELMEGPLSRYVAGEIEVSGSIPLLGGSLFGVATGYAVLGAPEGLYLYEEALHTVMKPPYLYRARLGFMGEMDKFGELRFGAAAEVIGNPGRGSVIVRVGPMLAIALTHHLDAVGTAMVVAATPDRLGLLGADLGQLGLRYRWATGDRWPEFP
>NC_021658.1|WP_148313257.1|683173_683941_-|phosphatase-PAP2-family-protein
MSEYVATGLLAATAFGTLAIPPSEGRWTTVNGFDGSARGALRIRSDRQREMARDASDLLLTLMTNHLAVDALLVTWWGHGRGSVAWEIAMIDIEALAFNAALNGVVAGLTSRERPYRAGCTGPEEQQDHDCRGSKRYRSFFSGHSSTAFTAAGLVCSHHAHLPLYGGGAPDALACAASLGTATAVATLRVVSDQHFATDALTGAAVGALTGFGLPWLLHYRGGAPASTSARAPRGDGVSIGFVPAPLGGYLVGRF
>NC_021658.1|WP_020732509.1|683921_684179_+|hypothetical-protein
MATYSLTRKRGQRGSHATSRRARSGGGAVVHATGAVVHATAAAPGVAGAGSACAAPGAAGAGSACGLRRRRAERRRRGERAGGGP
>NC_021658.1|WP_020732510.1|684213_684570_-|cupin-domain-containing-protein
MRQQIDGAVVLTAADEDATEYLPNRGVFFAQLLGKGLGQAFGFYKGTMDPGCEISRELHAETTETIYILSGKALGIVGDREVPLGPGQMMHVDKNVHHGLRNAGAGPLEFLVIGHPDF
>NC_021658.1|WP_020732511.1|684683_686441_-|DUF4139-domain-containing-protein
MATATSASGSDRAERSAGGGDAGGGDAGGGAEGGASAGGAGAAAGAPHPSAARVVTLFEDRAEVVRAARVEVGAGAQWIAIGGVSVFVDERTVQARVAGAGAEGAVRVTAARVRWRAHREAALGREAIDALSREQREASRRAGAAERARDRASRREAHLDQLLATWSQAMSEVPKDAGEPARLASWRAGVEALHAALAEALGASADARGARAHAEDDARRAAARLREGSIEQPRYEAVVEVEVHAPAPQPVEIELTYRVACAIWRPEHLARLSVAPAGAAAAGAGGAGAQGAGGSVELTTWAAAWQATGEAWENVTARFSTARPSRSAEAPLLADDVLRARRRAEVDRRRVVVEARDQAIATAGLGRGARAVDEMPGVDDGGEPLIFEAAEPVTLPSDGRPTRIEIARRSLPAELALVLYPEAHPAAHLRATVTLDGGGGRPRPLLAGPVKVARGGSLIGRARLDFVGAGEPFELGFGVDDAVRVRRTVDEEQDTSAITGSRKIRRRVKLSLSNLSSDVKRVLVTERIPVSEVADVEIALGEAPGWALDAEDGFLRGRVELPPKGLKTMSFSYELRAAASVVLPF
>NC_021658.1|WP_020732512.1|686460_688782_-|DUF4139-domain-containing-protein
MTAEKIECASRIEAVVVYARGAIVTRRVELAAPLPRGALEISVPGVTPLAEPGSFRALVAAAGGPPEAAAAAPREVVGVRARLVVPPAPVSRGALSAELRALELAIERLSAEHDHLRRWRDQLGAVALHPELARRFRPGDPAARIRDALAVSGLLSGELAALDARLAALDDELERARKALRSAQLDAAQATSGELEERAPARLDVVVRLAPTRDGSGGEPALRLEYAVGAARWWPAYAARFSRGATEVALQLDALVAQASGEDWKGVRVALATADLVQDTRLPELASLRLSRAQRPPRRGYRPAPEGLDAMFEGFDRFVAALPPPAARTTAAPAELPPPAPDDDDEPTLSRAAPGQASDELREAMARTAPPASSAGPRCRRLLAPEPPHRRCGASAPRPRGRPRPRRRPPRRCRSPRRCRPPRRCRPRRASRAGCRSPRSAAATGPPPPPPLQASAPEAPMAAFAHDASGERWAGTADELLDPGGELEGAGGAPAPVEPAQVEGWLDFDALHLPGTGPQRGRLARDEPGPSRRAARRAQMAIDDVGPPPRAVDPRDSRGQFDHLYAGESAADVPSNGRLHRVALSAARAPAAPRFVAVPRDAAEVYREARVENPFDAPLLAGPVEIFVDGALAAQSSLGHVDRGGLLRAGLGVEERIRVARNARVEESSAGLLGGSLSVEHAITIDLSSSLGVGVEVEVLDRIPVTDDKDVEIKLVSSHPRAEPYTQEDLGEPVRGGLRWRVPIAPGGKASVAFTYRVALSSKNEIVGGNRRE

Crispr_ID: NC_021658_4

• CRISPR_ID: NC_021658_4
• CRISPR_location: 2183485-2183586
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_4

Consensus_repeat	Method
GCGGCCGGCCGCCGCGGCTCTCGCTCCGGTGAGCGGCC	CRISPRCasFinder

spacers of NC_021658_4

>4.1|2183523|26|NC_021658|CRISPRCasFinder
GGCCGCCGCGGCCTGGAGCTCGCTGA

CRISPR arrays and Neighbor proteins around NC_021658_4

CRISPR arrays

The CRISPR arrays of NC_021658_4

>merge|NC_021658|4|2183485-2183586|CRISPRCasFinder
GCGGCCGGCCGCCGCGGCTCTCGCTCCGGTGAGCGGCCGGCCGCCGCGGCCTGGAGCTCGCTGAGCGGCCGGCCGCCGCGGCTCTCGCTCCGGTGAGCGGCC

>NC_021658|4|3|2183485-2183586|CRISPRCasFinder
GCGGCCGGCCGCCGCGGCTCTCGCTCCGGTGAGCGGCC	GGCCGCCGCGGCCTGGAGCTCGCTGA
GCGGCCGGCCGCCGCGGCTCTCGCTCCGGTGAGCGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020733539.1|2177693_2181284_+|kelch-like-protein	unknown	unknown	gnl|CDD|276965
NC_021658.1|WP_148313390.1|2195535_2196861_+|hypothetical-protein	unknown	unknown	gnl|CDD|238754
NC_021658.1|WP_020733538.1|2176937_2177294_-|DUF4398-domain-containing-protein	unknown	unknown	unknown
NC_021658.1|WP_044985609.1|2181969_2182911_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949446.1|2185664_2186657_+|DUF362-domain-containing-protein	unknown	unknown	gnl|CDD|377193
NC_021658.1|WP_020733550.1|2197241_2198546_-|guanine-deaminase	unknown	unknown	gnl|CDD|236419
NC_021658.1|WP_044985608.1|2173751_2174723_-|DUF4349-domain-containing-protein	unknown	unknown	gnl|CDD|379526
NC_021658.1|WP_044985612.1|2188621_2189776_+|hypothetical-protein	unknown	unknown	gnl|CDD|227244
NC_021658.1|WP_044987738.1|2173254_2173737_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020733548.1|2193769_2195155_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|237339
NC_021658.1|WP_020733546.1|2189841_2191575_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|226957
NC_021658.1|WP_148313389.1|2172316_2173165_-|hypothetical-protein	unknown	unknown	gnl|CDD|173412
NC_021658.1|WP_020733536.1|2175779_2176214_-|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NC_021658.1|WP_020733535.1|2175043_2175619_-|CDP-alcohol-phosphatidyltransferase-family-protein	unknown	unknown	gnl|CDD|273139
NC_021658.1|WP_020733542.1|2182962_2183202_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020733545.1|2186661_2188569_+|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|319895
NC_021658.1|WP_020733549.1|2197014_2197254_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044985611.1|2183753_2185562_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020733537.1|2176453_2176930_-|DUF4398-domain-containing-protein	unknown	unknown	unknown
NC_021658.1|WP_044987748.1|2192058_2193717_+|protein-kinase	unknown	unknown	gnl|CDD|270916

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020733539.1|2177693_2181284_+|kelch-like-protein	gnl|CDD|276965	sd00038, Kelch, Kelch repeat. Kelch repeats are 44 to 56 amino acids in length and form a four-stranded beta-sheet corresponding to a single blade of five to seven bladed beta propellers. The Kelch superfamily is a large evolutionary conserved protein family whose members are present throughout the cell and extracellularly, and have diverse activities. Kelch repeats are often in combination with other domains, like BTB and BACK or F-box domains.	8.87361e-37
NC_021658.1|WP_148313390.1|2195535_2196861_+|hypothetical-protein	gnl|CDD|238754	cd01477, vWA_F09G8-8_type, VWA F09G8.8 type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. The members of this subgroup lack the MIDAS motif. This subgroup is found only in C. elegans and the members identified thus far are always found fused to a C-Lectin type domain. Biochemical function thus far has not be attributed to any of the members of this subgroup.	0.00135048
NC_021658.1|WP_049949446.1|2185664_2186657_+|DUF362-domain-containing-protein	gnl|CDD|377193	pfam04015, DUF362, Domain of unknown function (DUF362). Domain that is sometimes present in iron-sulphur proteins.	7.6146e-55
NC_021658.1|WP_020733550.1|2197241_2198546_-|guanine-deaminase	gnl|CDD|236419	PRK09228, PRK09228, guanine deaminase; Provisional.	7.78706e-144
NC_021658.1|WP_044985608.1|2173751_2174723_-|DUF4349-domain-containing-protein	gnl|CDD|379526	pfam14257, DUF4349, Domain of unknown function (DUF4349). This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 282 and 353 amino acids in length. There is a single completely conserved residue D that may be functionally important.	9.25759e-47
NC_021658.1|WP_044985612.1|2188621_2189776_+|hypothetical-protein	gnl|CDD|227244	COG4907, COG4907, Predicted membrane protein [Function unknown].	5.29422e-07
NC_021658.1|WP_020733548.1|2193769_2195155_+|HD-domain-containing-protein	gnl|CDD|237339	PRK13299, PRK13299, tRNA CCA-pyrophosphorylase; Provisional.	2.41559e-89
NC_021658.1|WP_020733546.1|2189841_2191575_-|ABC-transporter-permease	gnl|CDD|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	4.27623e-64
NC_021658.1|WP_148313389.1|2172316_2173165_-|hypothetical-protein	gnl|CDD|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	1.22843e-06
NC_021658.1|WP_020733536.1|2175779_2176214_-|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.03467e-31
NC_021658.1|WP_020733535.1|2175043_2175619_-|CDP-alcohol-phosphatidyltransferase-family-protein	gnl|CDD|273139	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. Alternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis].	3.15973e-16
NC_021658.1|WP_020733545.1|2186661_2188569_+|4Fe-4S-binding-protein	gnl|CDD|319895	cd16373, DMSOR_beta_like, uncharacterized subfamily of DMSO Reductase beta subunit family. This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.	3.68547e-60
NC_021658.1|WP_044985611.1|2183753_2185562_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.02216e-38
NC_021658.1|WP_044987748.1|2192058_2193717_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.78197e-111

Protein sequences

>NC_021658.1|WP_020733542.1|2182962_2183202_+|hypothetical-protein
MSSALRAKVQGGRLVVDEPTSFAEGTVLELMVADNDDLDDAERAHLDEALEASLASAREATIDADELLAEIARLEPTRG
>NC_021658.1|WP_044985609.1|2181969_2182911_+|hypothetical-protein
MDARDGGAGRDGRRRSPGEVDMTKKSDIERWSDVVQQMNAAELPASTVPLHVLLGEAVDVAKFFEKYWKTQVDAQKRVTRLGLESAVPKDSKKGDAARLGPKTAEEILSLQRATQEAQTRYLLTVEKNKSPRERGKFLLGEIGATLSFYFDDGVEDERDEMLARIDAAHAGDPDTADALASALHDYATLGEKHRDALDGLGGFKAELLDEARAVAAELRSLPAQAEATSRQAQEALLLRNKLAALLIERMGRVRSAARFVFRSQPEIVREVTSAYERRKRAAARRSKAQPGPAPAAPPPAAPSPAVPAAPLDG
>NC_021658.1|WP_020733539.1|2177693_2181284_+|kelch-like-protein
MAQNVEPILTRSGPKPCAALGWAGGSLRAALLAPTFIGLAWLAGCARASAEGGDPGAPPLGEAPLADTAPSVSLGPWLSAAPMSAERANHTATRLLDGRVLVAGGETTRGALSAWYDSALSSAELYDPATGAWTAAPSMGSARSMHTATLLSNGKVLVAGGGTNGGHTPVPLVAAEIYDPAANVWTAVPPMEVPRLGHTATPLPDGRVLVAGGSSTGRPPEELASCAIYDPALNAWSAGGSMHRARSFYAATLLQDGKVFVSGGIDATAETYDPAADAWTPGTPMLMGLRSHTAMLLPGGEVLSLDTAAWGPHQIYSPATGAWRGLSMSGWEAPYSIDPADKRAVQLADGRALLSGGVTVESAPCGTADCEASAPPPVYFYYDTVGIYDAATDAWSMGPNMSQGRADHAATLLLDGTVLVTGGFAYGDGAWNEYATNTVERLAIAVDPGAPCGSSVDCGGRSCVDGVCCDTACDGACEACSVAAGATQDGVCSPLTGPACDDGDACTEADACQAGACAGAPVGDGAPCDDGDACTQSDACQAGACAGAPASDGTPCDDGDACTQSDACQAGACAGADPVACAAPAEGCQAPFCDPATGRCERALAPWGAPCDDGSACTQGETCAAGACIGGTATVVCEASGPCRASACDAATGACVESVLPDGALCEDGDACTEADTCQAGSCAPGAPKVCPAPSSCHAPAACDPSPGYASCGVPTVRPDGASCPDPTSSVWVEAAPPPEGLLHAGNSSTLLQDGTVLMAGGLTSTPEGSSIAASDAVRYDPEGDAWAPTGAMLHTRAYHTATLLPDGTVLVAGGLAAGGGASTAEAERYDPATGLWTAAAPMNAARNSHTATLLSNGKVLVAGGSVRVSRQSSAELYDPVANTWTPAAPMSTARASFSATLLVDGRVLVIGNKSSGSVGSEVYDPATDTWTEAFIMGWPTDDGHSATRLQDGKVLLVISDAGSWPTYPVMIFDPSTNTWTGVSRSSPRCEAERAALLADGRVLLLSCWATLPLPDRSAVKLYDPASDVWSLAPSFTQELWSHQPIPLPDGRVLTTAYVPARSAYAAWLYVPGAPASGDGVCAGGVCMALGGGGAGGEGGAGGDVSGTGGAGGGTSSGGGGGAAGSPSGAGGGGVGASAQGSSGASTPDSDGGAGGCSTARLPGGASGAPWLLLLSLLGARRQASRRRAPRARLDG
>NC_021658.1|WP_020733538.1|2176937_2177294_-|DUF4398-domain-containing-protein
MLARIALVMVSLELAGCAALRPPAPPPELARAETAIRGAAQEGAGADRRAAMHLALARSELAQARRRLSVGDLEAARWLLRRAEVDAELSTLIVREAGLRDAAGRTLDQASTLAEGAR
>NC_021658.1|WP_020733537.1|2176453_2176930_-|DUF4398-domain-containing-protein
MRAGAPLAMALSLAGCARGAAGPPPELATARAAVVQAQDNPLSPLAVAELKQAEQALAIAEREARERPRSAAARDAAYVARRRAQCSLLASLVRANQSALARARQTWKTWETAEELRARGASGAPEPAARDLPPALPDDVDLEPDVDRARARPQQPAR
>NC_021658.1|WP_020733536.1|2175779_2176214_-|universal-stress-protein
MKESANVILVPVDFEAASMKAVELAKDLGQRLGQKVVLLHVYQLPVYTYPGLEPALMPGFHAEVSAAASRAVQQLSAKTGGLDTALREGDPATEILAAAEEQRAAMIVMGTHGRRGLSHLFLGSVAQQVIRKSSVPVLTVRVPS
>NC_021658.1|WP_020733535.1|2175043_2175619_-|CDP-alcohol-phosphatidyltransferase-family-protein
MSTLSARELALPPNLMSLARLPLAALFPIVATRPALALAVLCCAGLTDVLDGWLARRSGQVTRTGAIVDPIADKVFALAVVATLLQSGALPLWGIPALLARELLELPLALWIAVSRRFRGARLSTASANIPGKLATAVQFGAVFTAIALPGALPAALAAAAGAGAAAGVSYWARQLRRAPGAAKGPPEAGG
>NC_021658.1|WP_044985608.1|2173751_2174723_-|DUF4349-domain-containing-protein
MRRTLPAWALLAVLAGPVACASSSSRAGDAASASMYPGSAPMYAATQASAPPPPDPTTGMEMSAVRISEEQAIDVDTSTSSVALAKAAPPAPVAAPAPGRGAPGPAQPAATSRPAPTSPAPQPGAAPAAAGPQGTQRGAAEASAAPAPLLVYTAQVAMAVFEVGASLGKVEELARDLGGFLARRDDRAITIRVPAARFDEALKRLEGLGDVVQRNVVAEDVTEEFLDLGVRIRNARVVRDRLEKLLEKAAKVEESIQLERELARVTSELERLEGRLKFLRDRVAFSTLTVSFQPRSTETITPSGPRLPIDWLNELGLSRLLNL
>NC_021658.1|WP_044987738.1|2173254_2173737_-|hypothetical-protein
MIHSLRHAFVLIASLAGAAAPLGCGRPFVPATPPGFVDLGDRYGDDEYRATTAEGLVLGVRAFENDPEGDLAFWSRVVEKRLREGGGYALLGKADVKSRSGLPGVQLRFGHDEGKEAHLYYLTVFVDDDHVFLHEAGGKKELVERHQQQIDWSIRNFLPD
>NC_021658.1|WP_148313389.1|2172316_2173165_-|hypothetical-protein
MRSRPMLCDARRRRSSQALLLALAASLGSGEALAHGEGERPLATVPAPPPGDGAKAAQILREIEGSVATAPPPAARDEADGGGKADGGGKADGGGKADGGGKADGGGKADGGGKADGGPARNAAKVVAEPVAQAKRALQRAHGARAAGDATNARRLDAVALEWAETARAVLRAAAVEAAAAEAAKQAREVETKLERARALLEETQARRGRAAAELERIEAEAREATRAATNVEAQRIEAGKKAAARGAAPRAERAPAAQGAGAKGSRDAGKAAAPAGKEGTP
>NC_021658.1|WP_044985611.1|2183753_2185562_+|serine/threonine-protein-kinase
MPPADPSLRTTMVHAFAVTVADPSSLVRTTSRGGTDDPATSSRGPSILPDVGQIVGGLYRLGRLLGQGMFGKVYVAQRIDVPEHQVALKLMPRSLYAMRNVERELVMLATVGHPHVVQLKDHGMNADYVWLTMPVYEGETLAQRLERSPLGMREAHDIFLAVARGLEALHTAGLRHQDVKPDNIFLARFAGRVHPILLDLGVAAEREASFCAGTALYASPEQIRALNGFPGVVPLSEKMDTYGLATTLLYSLVNPRDFPGESAQTRTELAASHDVRADKPLADNALPDLTGRPRQMFQDALRRWLAIDPNERPSMTQLAEELDVLLEPEREAEREAERLRIKQKTSYLRVRIAAGAMTLVGCAVVLLGFSKRETLRLANELEHARQKGAESFDKLDTCVASHQIAEAEKNACRTGRERDRAEFNETLATLQKSGSMTEAEHARQIQSLHATQAVRLKACEDDAAAAQKAAMADRERLAEAEKARAAMAVERDEAKALAEQRAAELAVATQLRAACDAERASCAAERDRLRAEAADPYDAPPSPGRPAAPAASGALPQLPPPPASAGAGAPPAAGASPAAGASPAAGATATPAASTPSNAAPP
>NC_021658.1|WP_049949446.1|2185664_2186657_+|DUF362-domain-containing-protein
MGDISRREVLRRLGAAGLVLGGAGGLAAARWDRGGTAVAAAERQQTRDYRLRDAPAGVPQLVVARAGAEALAGGAPDPAALVRKAVDALGGMRRFISRGDVVVVKPNIGWDRTPIHAANTNPKVVAEVVRLAYDAGAKSVIVTDASCNEPNRCFQRSGIWKAAYDVGAEVVIPAAHRFRGMRLKGEVLDDWPVYTPLVNADKVINVPIAKHHNLSKYTAAMKNWYGALGGRRNRLHQNIDVSIADLATFIQPTLTIVDAVRVLMRNGPQGGNVADAKDMHTVIATTDQVAADAYGCQLIGRKPEEIPYLKMGHERGLGTMHWQNLRLAEV
>NC_021658.1|WP_020733545.1|2186661_2188569_+|4Fe-4S-binding-protein
MADSDPTPAEPAHRPSAAAAAAAPAKASPHGATAPGATAPAAPTRAKPWTALLRKAGAIVRPGAKRRPGSGLPARKAIQVLVWVRRAVQAGCLGVFLYFLFQTGFRGSFASSEARVRLPLPVEGFLLADPFVGAMTLLSTHTVYRGLLWSLGILALTLVFGRVFCGWICPFGTLHHFFGWIFPSRYGKGGKRVEANKTYARQRVKYYLMYAFLAASVAGSVIGGLFDPICVAVRAIGLAVIPAAQYVAAVVTGSAAATGSRPVQAAADQAQDFLAASVWQTKQFYFHQAWFVGILFVAILFMNRFIPRFWCRVLCPLGAFLGVFARFALFGMQKDHAKCTDCNLCLVHCQGADSPQGGVKWRQDECHMCLNCENACPEDVIKFRFLPNRKSALVTPDTGRRTALATAAAGAVIIPTARIADVLDANYDHRVIRPPGSVEEREFLERCIRCAECMKVCPNNAIHPAFFEAGIEGLWTPIVIPRIGYCEHSCVLCGDVCPTGAIQKITEEQKMGIGQKPISIGTAFYDQGRCLPWSMSVPCIVCEEFCPTSPKAIWVEEVDIPKREPVPAEHGKEPPMKMVHVQRPHVDPSLCIGCGACEKVCPVQDKPAVYVTSVGETRSKTNVILLEDTDYNKAS
>NC_021658.1|WP_044985612.1|2188621_2189776_+|hypothetical-protein
MRTLRLFGIFSLAALWGAPGCGEPFTAAEASAASSSSSGGGGGGGDGGGGGGGGGGGAATSSSSSAGGGGEGGCAACKAGEFCTASDTCVRCADRVGALSFVAPTAIEVDGAKPAFPRVREEPGEGEGAATQRLVYVATFGSSDAQIATATGRPWTAGKVVESAAVNSPQSESGPLLLPVDARSPRADFPEGSLLFDRVLAGPGSLPLLFVADRLEASQAETLEALNPDGGSHSVAVAHGLWPYRYWFMNKHQEGGQITSRLLTMLAGDAEARELHIVLPGDCPAQGGDLAPWVTPDGSLLFFQTLYSERGDCAQASVLRSFYVRLGADGLPVPGEKARMLLASLEAEIAVMTPSLSPDECTLYVASDLDMVDRRQRLYAASRR
>NC_021658.1|WP_020733546.1|2189841_2191575_-|ABC-transporter-permease
MSYPLKVALYSAWIALNVVVLLVLAALIYDIATQRYTIRVALQYLGSKKRAFVSVGTTFAILGVALGVAALATVISVTGGFRTEFRDKVLGVNAHVLVIKYSTDFREYRSVMDQVAKVPGVIGAAPFSINPMMLTHGGATATNVLVKGVDPARSLGVGADGAAAPVLDLPRYVLPGGDLSGLRRPGAKPAERAPPPSPSLPDVPLLDKGARGALEPDAGEFDLLKAYEERILEDERKAAARDAGAEPAPSPAELDVPENAGAEEAELAIAEGAPQGAIEPEGGYGSKLPEDDELPPEVDPDPCADKERVAKLPGIVIGAGLAKNLSLDIGECVTVTSPTIGFSFSDGAIKPPVAKQFRVIALFEAGFEQYDTKLAYADLYETQAFYDHGDTVTGVEMKVDDIDNASNIAREITNLLSNGLYYTMDWEELNHGLFTALVVQQLLMSVVLGLIIVVAAFTVIATLIMVVLDKKKEIAVLKAMGSTDSEILRIFLYQGGIIGLAGTTLGLLLGVAVCKGLLVYGFPLDPKVYFISRLPVHATPQAFAITGDVAILICLLATVAPSLYAGRLRPAEGFRAQ
>NC_021658.1|WP_044987748.1|2192058_2193717_+|protein-kinase
MPPSFRAPPPLRQKTPRLGRQSEPDADEMSGRTSAAPISEAEPSLEIPPPDEVEPRERRPPGAKDPYIGTTFDHRYKIERLLGEGGMGFVYLARHKVIDKRVAVKVLRAELARDREIFERFVQEARAASSIGNPHIVDISDFGDLPDGSTYFVMEYLEGVSLAQLIDSPNELPMDRICHIALQLSAGLAAAHDAGIIHRDLKPDNVFVVARGSDPNFVKILDFGIAKVSTSTTTKLTRAGAVFGTPHYMSPEQAAGAPIDHRTDIYSLGVMLYELVSRQLPFNADNFMGILTQHMYKAPVPIRALVGGPDCPPGLEAVILKCLSKKPESRYQSMSDLHDDLERVRSGGVPGAVAEMMARSGGFNVPHDYFKTSKVIVPATPPSPPRSPWPRYVWVAGAAAAVGIVTAIFVIGASGSARDTAPQAQKPPVEAPTVRPAPAPPPAVQKTVVALAAVPETAVGYRNGVELRLPASIDVEQGQTVTIDIRAEGYHPSTVVLDGTEQSKLVKLVEVDEKGVSKVRPGGAPRPPPQTTAKPPKGSDVRDPWANQNQKK
>NC_021658.1|WP_020733548.1|2193769_2195155_+|HD-domain-containing-protein
MTQIAHLIDLVPEDVLGICRRLRERGKRGWIVGGCVRDLLRGEPAKDWDVATDARPEEVMAAFRKVIPTGIQHGTVTVMVRGVPYEVTTLRGDGTYSDGRRPDRVEFVDDITADLARRDFTMNAIALDPVDGHLIDPFGGQRDLEAKVIRAVGDPGERFAEDGLRVLRAARFAATLEGALDPETERAMGTARSHQTFRCVSAERVRDEWLKAMRARRPSVAFEIMRRTELLGITCPEMMESVGCEQNRWHAYDVWGHAMACLDACKPEPILRVAALMHDIGKPRTREFSDKTRDYTFYEHERVGAEMAEPILSRLRFSNDERARIVALIRHHLICYDDSWTDAAVRRWLRRVTPALAPDLYEIGVADALGKGREVTEDIATIGRLRARVEAMLAAGAALSAKDLAVNGSVLMRELGIPPSRLVGEILERLVELVTEEPEANTPERLLAAARELVAAKAADA
>NC_021658.1|WP_148313390.1|2195535_2196861_+|hypothetical-protein
MGLLAAAASIGGCSGGGGEASSGNNGSGSGSGGGGGGGDTTGSGIGDGGGFDFDGGTGDASLNEDTACVATKLQADYEQRPADIIFIIDNSESMTDEINSVQQNINQNFASIIERSGIDYRVIMLSKHGSSALEQSVCVEAPLGSGSCSPVPTAPNTNPPHFYQYSLEVSSLNSLCLAIDTLKGAIPPKGETTSPGWSQWLRPDSLKVFVEITDDGVDCSSISLGADPAKTDEGDIALKDVDDDDMETLAGGTKSAEVFDAALTATAPEYFGTPSARNYMFFSFVGIVENTDPTVPWPPEEPVTWEQCRPGSVDPGTTYQTLSVMTGGLRYPIQQYDTYDAVFQAIADSVISGAKLSCEIDVPKAPGGHSIDLETVQIEFTPSNGGQKQTFSQVKTPEECKPMSFYIEEGIIRLCPDTCAMAVQDNTAGMNLLYGCSVNPN
>NC_021658.1|WP_020733549.1|2197014_2197254_+|hypothetical-protein
MRVDVACRAGHGGSEEPVAFTLGERRVRVTEILDRWPGGDHLYFKVRGDDGARYILRRDFEILVWELEVYEASTDTYGE
>NC_021658.1|WP_020733550.1|2197241_2198546_-|guanine-deaminase
MSARPPESPRAYRGRLLTPLAAATNGAPVRYLDDALLVVGSDGRIVEAAPFAPGAFRGPVLDLRPSVLMPGFIDAHVHFPQTRIIGSASGSLLDWLERSVFPEEARFRDDGYAALVAGEFTARLAASGTTTCVVFSSSCAGATDQLFDALLRAGLRGIAGLTLMDQNCPEALCVRRDDAIAMARDLVQRWHGAGGGLLEFAITPRFALSCSRGLMEAAALLAHDHGLLVQTHVAETPAEGEATLREHPWARDYIDVYDRVGLLTGRALLAHGIHLTPREWDRLAETRSSVVHCPDSNFFLGSGRMRLADARARAVSVGLGSDVGAGRSFDMRRSMSSAFDNALCLGDRLLPSALFVMATQGTADAIGLGRVIGSLETGKEADFIAVRFPEHLLGEAELLNHLVFAPETAAVHRAFVRGRPVPLRRLGAHPHHSP

Crispr_ID: NC_021658_5

• CRISPR_ID: NC_021658_5
• CRISPR_location: 2641533-2641638
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_5

Consensus_repeat	Method
GCTCCTTTGCAATTGCAAGCATCGCGCCGG	CRISPRCasFinder

spacers of NC_021658_5

>5.1|2641563|46|NC_021658|CRISPRCasFinder
ATCGCCCGCCGCCGAATCCCGCGCTGTGCCGGCGCCGCTCAGGCAC

CRISPR arrays and Neighbor proteins around NC_021658_5

CRISPR arrays

The CRISPR arrays of NC_021658_5

>merge|NC_021658|5|2641533-2641638|CRISPRCasFinder
GCTCCTTTGCAATTGCAAGCATCGCGCCGGATCGCCCGCCGCCGAATCCCGCGCTGTGCCGGCGCCGCTCAGGCACGCTCTTTTGCAATTGCAAGCATCGCGCCGG

>NC_021658|5|4|2641533-2641638|CRISPRCasFinder
GCTCCTTTGCAATTGCAAGCATCGCGCCGG	ATCGCCCGCCGCCGAATCCCGCGCTGTGCCGGCGCCGCTCAGGCAC
GCTCTTTTGCAATTGCAAGCATCGCGCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_049949873.1|2642128_2642524_+|GFA-family-protein	unknown	unknown	gnl|CDD|226314
NC_021658.1|WP_020733887.1|2637052_2638297_+|MFS-transporter	unknown	unknown	gnl|CDD|340929
NC_021658.1|WP_020733881.1|2630551_2631136_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274834
NC_021658.1|WP_044985670.1|2644265_2645357_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|378820
NC_021658.1|WP_020733882.1|2631267_2632584_-|Zn-dependent-exopeptidase-M28	unknown	unknown	gnl|CDD|367920
NC_021658.1|WP_020733880.1|2629498_2630341_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|188121
NC_021658.1|WP_020733891.1|2642574_2643738_-|hypothetical-protein	unknown	unknown	gnl|CDD|378123
NC_021658.1|WP_063751970.1|2646673_2647819_-|heparin-lyase-I-family-protein	unknown	unknown	gnl|CDD|372911
NC_021658.1|WP_020733885.1|2635015_2635903_+|phytanoyl-CoA-dioxygenase-family-protein	unknown	unknown	gnl|CDD|368580
NC_021658.1|WP_148313429.1|2634210_2634753_-|cytochrome-c-nitrite-reductase-small-subunit	unknown	unknown	gnl|CDD|274453
NC_021658.1|WP_020733892.1|2643817_2644243_+|VOC-family-protein	unknown	unknown	gnl|CDD|319916
NC_021658.1|WP_187345894.1|2640148_2641276_-|cellulose-binding-domain-containing-protein	unknown	unknown	gnl|CDD|366161
NC_021658.1|WP_020733886.1|2635911_2637039_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044987889.1|2632737_2634180_-|ammonia-forming-cytochrome-c-nitrite-reductase-subunit-c552	unknown	unknown	gnl|CDD|349426
NC_021658.1|WP_020733895.1|2646156_2646522_-|DUF2089-domain-containing-protein	unknown	unknown	gnl|CDD|378280
NC_021658.1|WP_020733898.1|2648840_2649128_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044985669.1|2638680_2639889_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NC_021658.1|WP_148314751.1|2645503_2646160_-|YIP1-family-protein	unknown	unknown	unknown
NC_021658.1|WP_020733897.1|2647939_2648821_-|hypothetical-protein	unknown	unknown	gnl|CDD|185702
NC_021658.1|WP_148314752.1|2649141_2649642_-|LEA-type-2-family-protein	unknown	unknown	gnl|CDD|377000

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_049949873.1|2642128_2642524_+|GFA-family-protein	gnl|CDD|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	1.53212e-23
NC_021658.1|WP_020733887.1|2637052_2638297_+|MFS-transporter	gnl|CDD|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.59421e-52
NC_021658.1|WP_044985669.1|2638680_2639889_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	9.85434e-93
NC_021658.1|WP_044985670.1|2644265_2645357_-|alpha/beta-fold-hydrolase	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	3.81272e-07
NC_021658.1|WP_020733882.1|2631267_2632584_-|Zn-dependent-exopeptidase-M28	gnl|CDD|367920	pfam04389, Peptidase_M28, Peptidase family M28.	5.10157e-39
NC_021658.1|WP_020733880.1|2629498_2630341_-|alpha/beta-fold-hydrolase	gnl|CDD|188121	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily. This model describes a subfamily of the alpha/beta fold family of hydrolases. Characterized members include prolinases (Pro-Xaa dipeptidase, EC 3.4.13.8), prolyl aminopeptidases (EC 3.4.11.5), and a leucyl aminopeptidase.	2.14918e-26
NC_021658.1|WP_020733891.1|2642574_2643738_-|hypothetical-protein	gnl|CDD|378123	pfam09113, N-glycanase_C, Peptide-N-glycosidase F, C terminal. Members of this family adopt an eight-stranded antiparallel beta jelly roll configuration, with the beta strands arranged into two sheets. They are similar in topology to many viral capsid proteins, as well as lectins and several glucanases. The domain allows the protein to bind sugars and catalyzes the complete removal of N-linked oligosaccharide chains from glycoproteins.	2.54255e-16
NC_021658.1|WP_063751970.1|2646673_2647819_-|heparin-lyase-I-family-protein	gnl|CDD|372911	pfam14099, Polysacc_lyase, Polysaccharide lyase. This family includes heparin lyase I, EC:4.2.2.7. Heparin lyase I depolymerizes heparin by cleaving the glycosidic linkage next to an iduronic acid moiety. The structure of heparin lyase I consists of a beta-jelly roll domain with a long, deep substrate-binding groove and an unusual thumb domain containing many basic residues extending from the main body of the enzyme. This family also includes glucuronan lyase, EC:4.2.2.14. The structure glucuronan lyase is a beta-jelly roll.	5.1438e-30
NC_021658.1|WP_020733885.1|2635015_2635903_+|phytanoyl-CoA-dioxygenase-family-protein	gnl|CDD|368580	pfam05721, PhyH, Phytanoyl-CoA dioxygenase (PhyH). This family is made up of several eukaryotic phytanoyl-CoA dioxygenase (PhyH) proteins, ectoine hydroxylases and a number of bacterial deoxygenases. PhyH is a peroxisomal enzyme catalyzing the first step of phytanic acid alpha-oxidation. PhyH deficiency causes Refsum's disease (RD) which is an inherited neurological syndrome biochemically characterized by the accumulation of phytanic acid in plasma and tissues.	2.89246e-11
NC_021658.1|WP_148313429.1|2634210_2634753_-|cytochrome-c-nitrite-reductase-small-subunit	gnl|CDD|274453	TIGR03153, cytochr_NrfH, cytochrome c nitrite reductase, small subunit. Members of this protein family are NrfH, a tetraheme cytochrome c. NrfH is the cytochrome c nitrite reductase small subunit, and forms a heterodimer with NrfA, the catalytic subunit. While NrfA can act as a monomer, NrfH can bind to and anchor NrfA in the membrane and enables electron transfer to NrfA from quinones. [Energy metabolism, Electron transport].	1.41546e-62
NC_021658.1|WP_020733892.1|2643817_2644243_+|VOC-family-protein	gnl|CDD|319916	cd07253, GLOD5, Human glyoxalase domain-containing protein 5 and similar proteins. Uncharacterized subfamily of VOC family contains human glyoxalase domain-containing protein 5 and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.55667e-19
NC_021658.1|WP_187345894.1|2640148_2641276_-|cellulose-binding-domain-containing-protein	gnl|CDD|366161	pfam00553, CBM_2, Cellulose binding domain. Two tryptophan residues are involved in cellulose binding. Cellulose binding domain found in bacteria.	2.79711e-10
NC_021658.1|WP_044987889.1|2632737_2634180_-|ammonia-forming-cytochrome-c-nitrite-reductase-subunit-c552	gnl|CDD|349426	cd00548, NrfA-like, cytochrome c nitrite reductase and similar proteins. This family contains cytochrome c nitrite reductase (also known as cytochrome c552, or NrfA) and similar proteins. The pentaheme enzyme NrfA catalyzes the electron reduction of nitrite to ammonia in the nitrogen cycle. This enzyme can also transform nitrogen monoxide and hydroxylamine, two potential bound reaction intermediates, into ammonia. It is a homodimer, with each monomer containing four classical CXXCH type heme-binding sites along with an alternative CXXCK heme-binding motif, which is important for catalysis. This family also includes octaheme nitrite reductase (TvNiR) from the haloalkaliphilic bacterium Thioalkalivibrio paradoxus which catalyzes the reduction of nitrite and hydroxylamine to ammonia as well as the reduction of sulfite to sulfide.	0
NC_021658.1|WP_020733895.1|2646156_2646522_-|DUF2089-domain-containing-protein	gnl|CDD|378280	pfam09862, DUF2089, Protein of unknown function (DUF2089). This domain, found in various hypothetical prokaryotic proteins, has no known function. This domain is a zinc-ribbon.	8.24117e-43
NC_021658.1|WP_020733881.1|2630551_2631136_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274834	TIGR03885, putative_dehydrogenase_protein, probable non-F420 flavinoid oxidoreductase. This model represents a clade of proteins within the larger subfamily TIGR03557. The parent model includes the F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554) and many other proteins. Excepting the members of this family, all members of TIGR03557 occur in species capable of synthesizing coenzyme F420. All members of the seed alignment for this model are from species that lack F420 biosynthesis. It is suggested that members of this family bind FMN, or FO, or a novel flavinoid cofactor, but not F420 per se. [Unknown function, Enzymes of unknown specificity].	2.35898e-113
NC_021658.1|WP_020733897.1|2647939_2648821_-|hypothetical-protein	gnl|CDD|185702	cd09025, Aldose_epim_Slr1438, Aldose 1-epimerase, similar to Synechocystis Slr1438. Proteins similar to Synechocystis Slr1438 are uncharacterized members of aldose-1-epimerase superfamily. Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism, catalyzing the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family, galactose mutarotase, have shown a glutamate and a histidine residue to be critical for catalysis; the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen.	6.67155e-120
NC_021658.1|WP_148314752.1|2649141_2649642_-|LEA-type-2-family-protein	gnl|CDD|377000	pfam03168, LEA_2, Late embryogenesis abundant protein. Different types of LEA proteins are expressed at different stages of late embryogenesis in higher plant seed embryos and under conditions of dehydration stress. The function of these proteins is unknown. This family represents a group of LEA proteins that appear to be distinct from those in pfam02987. The family DUF1511, pfam07427, has now been merged into this family.	1.14643e-07

Protein sequences

>NC_021658.1|WP_187345894.1|2640148_2641276_-|cellulose-binding-domain-containing-protein
MRTNRLLGYISASLACSLLACGAGSHSDENSGTLGSALVSPDGTMTAEITVPSDWKSGYCASVTIKNTGSSAATSWGMVIGLNGSTLNHAWNTRITPSDGQIRAVNESYNGKLDPGASTMWGFCGSGTGRPTLVSVDGTGGPDVSTSTSVSSSVGSGGATGVGGSGGEGGEGGGTTTTGTGGEGGGTTTTGAGGEGGGTTTTTGAGGEGGAEVTTGTGGEGGAGGEGGAGGATTPAGAGGEGGAGGGSTTAGTGGAPPLDPACGPDTATFADVEPILVKSCANQFCHGNPTSPAGRLDLRASAAVGALVNQDAGSCSSEKALVVPFMPSDSYLMNKLKDVGLCDPDESSMPPGSSLPEAELKTINDWICAGAPDR
>NC_021658.1|WP_044985669.1|2638680_2639889_+|cytochrome-P450
MSPLIDVLAPGLRANPHPYYAEMRRTSPVCQVDPGGMWAVTRYEDVLFVMKNPGLFSSEGFKVAWQPPWVGYNPFANSMLAMDPPAHTRLRGLIHRAFGAATVARLEPRLRAVATELTNRLVEEADFVEAFGHPLPAFAIGEILGLDHALHAKFKRWADDIVSITPELPSPEDAQRVRTTLAELTGYLMEVIAKRRRAPVDDTVSDLVRAELDGQRLTDAEIVEFLVTLLIGGLETTTHLLSNSLLFLADHPDMMERLHADPGLISPFVEEMLRYDGPVQTLPRIATADVVLSGVTVPRGALVLPIVASANRDEARFKDPDRFDLHRGSQGGLHWGHGVHFCIGAALARMEARVALEAVIARFERVERVPHELRYNRTLTVRGPITLPLRFIPARRTGQQVG
>NC_021658.1|WP_020733887.1|2637052_2638297_+|MFS-transporter
MTTAAPQRKTPFTPYQRRLFWFLSVASFFEGYDYLALTQILPNIGAEMGLAARHEGLLVGFINAGTMIAYLLVRKADEWGRRRVLTITILGYTLFSVLTGFAPNVYVFAVFQLLARIFLLGEWAVSMVYAAEEYPSDRRGMVIGVIQAFSSLGSIVCAGVVPLLLSTSYGWRSVYFVGGIPLLIMAVARRGLRETARFEQAAAAREAEGAQPFMRIWSSPYRGRMLQLALIWGLTYVCTQNAVTFWKTFALRERGFTDAEVGASITFAALVSMPLIFVSGKLLDVMGRRAGAVIIYLLAAVGVLGAYSLGSRAGLTVALVFAIFGASGVLPVLNAYNAELFPTHLRGDALAWSNNLLGRIGYILSPVAVGVAAERMGWGPAVSATAIFPVLALALILWLLPETRGKELEETARV
>NC_021658.1|WP_020733886.1|2635911_2637039_+|hypothetical-protein
MSIAIEEAKSAADLADILDLPLRLHAADPGYVPPLRPLVLRRLDPRNPFFREASLRLFRARRGRETVGSISLLVDGRHDRHSGERTAFFGFFECERDPEAARALFGAVSERARALGATSLRGPRNVTRVEDIGLLIEGYGSRPPMLAGHHPPYYRELVEAEGFSKRYDMLAYDTPLFDAAGRRRELPDALRRKAAAVSIPGLEVRRAAVHRISRDMEIVHAVFTEAYRGVPEVVPMSRAEFVNLGRAFALLSNPRLLQIATVRGEPAAFAVCLPDLNEALAAARGRLLPLGWARAAWALRRVRTASFKLIGVVPAFRSTGLYALLVQHVVDGLRAAGYDRLEASLIHEDNAPMRHIVESAGCSIYRRYRVYEGPL
>NC_021658.1|WP_020733885.1|2635015_2635903_+|phytanoyl-CoA-dioxygenase-family-protein
MNTVRAPQPAAVPREPQPAAGLPPANRRIRLPDFTLGGALTAEQRDFLDTHGFIRFRGFAGRDAVRSLVEEVEDIDRRLVGEGRTHINGVPLILGARKDGSRYIQRMVFASLFGERLRAFLRDPRFGAILDAAGPGYRIAERERDGLVINHYRREEGSTYQRLGWHTDSLRDVFYLERPRRYLNVGFYLDDSPLSKGGVRLIPSSHRQGLFEMITRKAYFLDHRPDPDEYALEAEAGDLTIHDGRIWHRVAQASATGDASQRRVMYLPLMCGPLKEKHENSPTPLYFRLKRLAGY
>NC_021658.1|WP_148313429.1|2634210_2634753_-|cytochrome-c-nitrite-reductase-small-subunit
MSDPPEPVAEEQQRGEPPMAPVRGSARRARGILSWGLPLALCVALGAAVGLGGYTFLYAKGASYLQNDPSACANCHIMNEQFDGWQRSSHRAVAGCNDCHAPHTFLGKYATKASNGFWHSFAFTTGRFPDPIRIKPGNLRITEEACRGCHGDVVHAIDSEHRGAPRLSCVRCHESVGHLH
>NC_021658.1|WP_044987889.1|2632737_2634180_-|ammonia-forming-cytochrome-c-nitrite-reductase-subunit-c552
MTEPKDERSTTESAKKPAFQRYLPLITIAAAAASAGTAALLVNIFEHKQEAKSPFYRVVELDDTIEDPAVWGKNFPIQYDGYRRTVDQKRTRYGGSEAVPRTPTEADPRSVVAQSKLEEDGRLKTMWAGYAFARDFREERGHAYMLEDQVYTERQIATKQPGTCIHCHASVYVPYKKLGGGDLMRGWEAMNQMPFPEARKLVTHPVSCIDCHDPESMQLRVTRPGFLEGIRALKASMGEADYDVNTMATRQEMRSYVCGQCHVEYYFKGPEKRLVYPWAKGIKVDEIYAYYEETGHADWTHAESGAKVLKAQHPEFEMWNQGVHARSGVACADCHMPYQRVGAAKVTDHHIQSPLLNINRACQTCHKWPEDELRQRVETIQGRHAETRDRAMDAVTALIGDIRRAKEAGAADEALAEARAAQRKCQFFVDFAEAENSSGFHAPQEAMRILASAIDTCRRGQLALRGGSNPPSGLVEPPAN
>NC_021658.1|WP_020733882.1|2631267_2632584_-|Zn-dependent-exopeptidase-M28
MATRRNRSSAAAAGCAVFALISASCASGDPGAPAAETIHVSHVEKDTVSTFLNRLATETGQVVVTRAAAPGAWQSAPLTHDHESSLHLVEGPLPAAPLPGERARVGGIAVVAVPAGREPHGWLGSHRYHTEPIAETEVVLSGARGRQGAPAPARRSAAFEGDPADVRIDAEFLEARLKELSGAVPVTLGGRTVTLRERGSESGRSLARAWLRQQYEALGFTVQEHPYRSGWSQGVNVTADKPGADPSRVLILSAHYDSVSNAGADDDGSGVVSSLAIARALKDARLSIGLRVVAFDQEEIGLLGSKAYASMLDRNGQLDQVVGVLDLEMTGYDSNDDGRYHAIHCNENTSSELGALVEAAATRGELGLARVDACTNRSDHAAFWRYGTPSVAVSQNFFGDDGNPCYHARCDTVAQLNWDYMRRLTQAVALAAADLLIE
>NC_021658.1|WP_020733881.1|2630551_2631136_-|LLM-class-flavin-dependent-oxidoreductase
MRKLAIGYHASHEQLAPSALLRHVRHAEQAGFAASMCSDHFHPWSENQGESGFAWAWLGAALQATSLSFGTVCAPGYRYHPAVIAQAAATLAEMYPGRFWLSIGSGEALNEHITGEKWPDHAERTARLEECAEILRALWRGETVTHRGRVVVEGAKLYTRPAAPPLLLGAAISPATAARVGRWADGLITVSCTT
>NC_021658.1|WP_020733880.1|2629498_2630341_-|alpha/beta-fold-hydrolase
MRVQAGDVRLFFEVEGAKLVPDGPAMRERPTVILLHGGPGVDHTDFVPFGSALADVAQVVYLDHRGCGRSDRSGPERWNLATWADDVRAFCDALEIQRPVVLGNSFGGMVAQAYAARYPDHPGKLILTSTTAKLRLDRMLPVFERLGGARAADVARRFFADPMPNFHDYIRVCFPLYRQTPADEGALQRAVIHLDVGGYFVGGEMQTYDLRADLARVRCPTLVLSGDLDPFATSADARDLVAALPGELVQARHFPHAGHAVLADAGAEALAAIRGFLGAT
>NC_021658.1|WP_049949873.1|2642128_2642524_+|GFA-family-protein
MLTGSCYCGLVRFEVDDAFDYAFYCHCSRCRRRTGAACSAVGGIAIDKVKISAGREHLLKVDESEEGYRGLCDRCFSPLYDTVRGNTFAHVQLGALSKAPERRPDHHIYVGSKAAWHPITDDLPQFEELPP
>NC_021658.1|WP_020733891.1|2642574_2643738_-|hypothetical-protein
MSGSRCTRRALAGALGFAVVLGGSGCSDDAARAPGEAQPGAGGAGGRGGEEQEPSPAPAYTITAFEEVRITSDASQPNFQQANADIDLRDGPFASVRLVVELESTCYPFETWEDNPPPEGQSWPADCDAFDRNFELSLDDPVDPAADPPGIELVRAITPFGGPLRLEVDITDVANGLPAGKHRLRVVIPTWSDGSGQVSGSNGGWNVSAVVEAVPGPAPRKVLAVVPLFYGSQTTADGPGPLAVEVPEGTVSSRVEYRITGHGGGESGSGCIGPAEEFCRRIHTLFVDGSELARVRPWRTDCEALCTIAHYGPEDGGFDYCLENPCGAIESVRAPRANWCPGSESPPFTWDADALRVPGQHTLAWEISTIAEGGVWRVSATYFAFGE
>NC_021658.1|WP_020733892.1|2643817_2644243_+|VOC-family-protein
MALHVDHVVLWVEDPLRALEFYTRVVGLTSVRAEEFRAGQAPFPSVRLSEASILDLMPNSITEFVRKATGETRPSAAGRPINHVCFAMDRDEFDALAARLSAARVAMHTANDPSFGARGASVHWFYFQDPDGNMLEARYYP
>NC_021658.1|WP_044985670.1|2644265_2645357_-|alpha/beta-fold-hydrolase
MSLRSSLLVPARRAAFVLSCAVALAGSPFGVGCGAGEGESSAGGDGALPDETEPPPAPDTPPCPEAATSVDLTVENAYGTLEGTLEVPAGCGPFPSVVILPGSGPTDRDGNQAAAGVAADTYRLLAEGLRDRGVASIRYDKAGIGGSASAAPRSEQELRFEMGADDAVLWVKALRDDGRFATVTVVGHSEGSLLGMLAAQAIDVDGYASIAGAGRPIGEVLRDQLAGLPDEDRERAYEILGRLEAGELVEDVPQTELFLSLFRPSVQPYIISWMKRDPAVELAAVKAPILLLQGTADIQVGVQEAERLAGARPDARLVLIEGMSHTLKEATLSSASQQAAYADPSLPVVPRVLEEIAALLRAE
>NC_021658.1|WP_148314751.1|2645503_2646160_-|YIP1-family-protein
MMRITPDERVRALVRDHVIEPAEGERLLATMSPRPPQVGWRLALDPFERFGGEIAAVAGLAVAGLSVAITRLGVRFDGFLDLHMAPEVVPITTALVEQVVVWPLPALLFWAYARLLRCRVRFVDFLGVTGLSRAPLALAAVVLGLLAPAPPAAGGPVLTPAVAAFAVLAALCLAWFLTLLTRGFKNASGLRGAPLIAGLIGLVLVAEIVSKVALTRLG
>NC_021658.1|WP_020733895.1|2646156_2646522_-|DUF2089-domain-containing-protein
MARFVVRCPSCDGELRATRLGCQACGTNLDGQFEIPALLQLSPDDLAFVTAFVRSSGSLKAMSQLLQISYPTVRNRLDEIIGRLEALEQGVQRRRHEILDALEHGRLSAKEAEEALRKVGL
>NC_021658.1|WP_063751970.1|2646673_2647819_-|heparin-lyase-I-family-protein
MTSRTHLTAHRSLFLRCRALLGRRPRFLLSALPAAALVATVATGASAAPVWTGDFETGDLSQWNTSLNGEHISVVTSPVLQGTRAGQIQLTNDAVWPGNGIKRVELNHKPAAGRTAEGAQTYFAWSFYLPEALAADPPTQIGYWESDGSYNQVMSFEVVGQNISFATRKPANKVHWQANGAVTPGVWHRIALHVKWSTNPSQGSVDVWFDGEQVVTAGQAQTLADGNPHFTQLGLLRNPSEFTDSPILILDDAVEGDTLEDVRPALPSSGEGGAGGAGGGGTGGGDNTGGAGGAGGATSGSGGAGGGTTIGSATSTSSAATSGAATTGTGAGTGGADEGADEEGDEGGCSCRAAGSPAAPTPLALAGLAVALAFARRRARR
>NC_021658.1|WP_020733897.1|2647939_2648821_-|hypothetical-protein
MFSVKQIEGAIPAVELVDGDASSRAVLAPARGGILTELTLGGRELLYLDRATFEDRSANVRGGNPVLFPSPGKLAGDAWSSSGAQGQMRQHGFARALPWSLDDRGTAAPGGAYARLALRSSEATRAQYPWDFRAELTYTLRGRSLRIDVRVTNETGEGAPPMPFGVGFHPYFAVAQADKPRASIETRATRAFDNTTKQEVPFSGFDLTRPEVDLHLLDHGSTESALSIEGPRAARIAVRGSPEFTHWVVWTLQGKDFVCLEPWTCPGNALNTGERLIHLPARETQALWIEISA
>NC_021658.1|WP_020733898.1|2648840_2649128_-|hypothetical-protein
MSGGLIFHDGGGGPVARCGRCGAEAAGPCARCRAPVCGDCCVLTEGGARVWAICLACEDRGGRSLRRGWAMVLGWIALPIAALALLVGLLEWLRR
>NC_021658.1|WP_148314752.1|2649141_2649642_-|LEA-type-2-family-protein
MSAVRSPLLAAALSLVACSRPEPPTLKPEVAAVTAVTAQGIDLRVQIQAYNPNSVDLSTRSLKATVLLDGKIDVGTVTVPTPLKLRSKQWTRIDAPLSVKWQDLTSIAALAAQGRGVPYQVNGTVAIGGETLNVDVPFRLAGTLTQEQLVTVIGNSLPVLPLPGLR

Crispr_ID: NC_021658_6

• CRISPR_ID: NC_021658_6
• CRISPR_location: 3417681-3418202
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of NC_021658_6

Consensus_repeat	Method
GGAGCTGGTGGAGGCGGCGGAGCCGGAGCT	CRT

spacers of NC_021658_6

>6.1|3417711|78|NC_021658|CRT
GGCGGGCGCGCCGCCTGCTGCCGGCGAGGGTGATGGAGCGGAGGCCGCGAGCGTGGTGGGCGGCGAGGCGGCGGAGCC
>6.2|3417819|66|NC_021658|CRT
GGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCC
>6.3|3417915|42|NC_021658|CRT
GGTGGAGGCGGCGGAGCCGGTCGAGCCGGAGGCGGCGGAGCC
>6.4|3417987|42|NC_021658|CRT
GGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCC
>6.5|3418059|18|NC_021658|CRT
GGTGGAGGCGGCGGAGCC
>6.6|3418107|18|NC_021658|CRT
GCCCGTGGAGGACAGGAG
>6.7|3418155|18|NC_021658|CRT
CGTGGAGGCGGCGGAGCC

CRISPR arrays and Neighbor proteins around NC_021658_6

CRISPR arrays

The CRISPR arrays of NC_021658_6

>merge|NC_021658|6|3417681-3418202|CRT
GGAGCGGGTCGAGGCGGCCGGGGGCGAAGAGGCGGGCGCGCCGCCTGCTGCCGGCGAGGGTGATGGAGCGGAGGCCGCGAGCGTGGTGGGCGGCGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGTCGAGCCGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCTGGTCGAGCCCGTGGAGGACAGGAGCATGCTGGTGGAGGCGGCGGAGCCGGAGCTCGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCT

>NC_021658|6|3|3417681-3418202|CRT
GGAGCGGGTCGAGGCGGCCGGGGGCGAAGA	GGCGGGCGCGCCGCCTGCTGCCGGCGAGGGTGATGGAGCGGAGGCCGCGAGCGTGGTGGGCGGCGAGGCGGCGGAGCC
GGAGCTGGTGGAGGCGGCGGAGCCGGAGCT	GGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCC
GGAGCTGGTGGAGGCGGCGGAGCCGGAGCT	GGTGGAGGCGGCGGAGCCGGTCGAGCCGGAGGCGGCGGAGCC
GGAGCTGGTGGAGGCGGCGGAGCCGGAGCT	GGTGGAGGCGGCGGAGCCGGAGCTGGTGGAGGCGGCGGAGCC
GGAGCTGGTGGAGGCGGCGGAGCCGGAGCT	GGTGGAGGCGGCGGAGCC
GGAGCTGGTGGAGGCGGCGGAGCTGGTCGA	GCCCGTGGAGGACAGGAG
CATGCTGGTGGAGGCGGCGGAGCCGGAGCT	CGTGGAGGCGGCGGAGCC
GGAGCTGGTGGAGGCGGCGGAGCCGGAGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020734444.1|3411567_3412284_-|peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl|CDD|372650
NC_021658.1|WP_020734440.1|3408854_3409460_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227302
NC_021658.1|WP_020734454.1|3426470_3427223_+|nickel-pincer-cofactor-biosynthesis-protein-LarB	unknown	unknown	gnl|CDD|224605
NC_021658.1|WP_020734438.1|3406963_3407560_-|hypothetical-protein	unknown	unknown	gnl|CDD|227070
NC_021658.1|WP_063752129.1|3422995_3423625_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NC_021658.1|WP_020734455.1|3427291_3428668_+|nickel-pincer-cofactor-biosynthesis-protein-LarC	unknown	unknown	gnl|CDD|376691
NC_021658.1|WP_020734446.1|3413340_3414177_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949483.1|3414187_3416542_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020734458.1|3430601_3431741_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_021658.1|WP_020734452.1|3423898_3425239_-|PmbA-protein	unknown	unknown	gnl|CDD|182922
NC_021658.1|WP_020734439.1|3407553_3408858_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227301
NC_021658.1|WP_049949484.1|3428772_3429429_-|thioredoxin	unknown	unknown	gnl|CDD|200072
NC_021658.1|WP_020734450.1|3420774_3421119_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197775
NC_021658.1|WP_063751977.1|3409456_3410185_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227305
NC_021658.1|WP_044985757.1|3410262_3411447_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314776.1|3422300_3422795_+|lamin-tail-domain-containing-protein	unknown	unknown	gnl|CDD|376421
NC_021658.1|WP_020734457.1|3429609_3430605_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_021658.1|WP_020734445.1|3412334_3413183_-|MaoC-family-dehydratase-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|178455
NC_021658.1|WP_044985756.1|3403296_3406947_-|hypothetical-protein	unknown	unknown	gnl|CDD|225953
NC_021658.1|WP_020734453.1|3425437_3426190_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020734444.1|3411567_3412284_-|peptidyl-prolyl-cis-trans-isomerase	gnl|CDD|372650	pfam13616, Rotamase_3, PPIC-type PPIASE domain. Rotamases increase the rate of protein folding by catalyzing the interconversion of cis-proline and trans-proline.	1.10002e-24
NC_021658.1|WP_020734440.1|3408854_3409460_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227302	COG4967, PilV, Tfp pilus assembly protein PilV [Cell motility and secretion / Intracellular trafficking and secretion].	1.42479e-07
NC_021658.1|WP_020734454.1|3426470_3427223_+|nickel-pincer-cofactor-biosynthesis-protein-LarB	gnl|CDD|224605	COG1691, COG1691, NCAIR mutase (PurE)-related proteins [General function prediction only].	2.4589e-79
NC_021658.1|WP_020734438.1|3406963_3407560_-|hypothetical-protein	gnl|CDD|227070	COG4726, PilX, Tfp pilus assembly protein PilX [Cell motility and secretion / Intracellular trafficking and secretion].	0.00335562
NC_021658.1|WP_063752129.1|3422995_3423625_+|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	2.04662e-09
NC_021658.1|WP_020734455.1|3427291_3428668_+|nickel-pincer-cofactor-biosynthesis-protein-LarC	gnl|CDD|376691	pfam01969, DUF111, Protein of unknown function DUF111. This prokaryotic family has no known function.	2.26331e-171
NC_021658.1|WP_049949483.1|3414187_3416542_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	9.57289e-86
NC_021658.1|WP_020734458.1|3430601_3431741_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	4.09299e-48
NC_021658.1|WP_020734452.1|3423898_3425239_-|PmbA-protein	gnl|CDD|182922	PRK11040, PRK11040, peptidase PmbA; Provisional.	5.68855e-107
NC_021658.1|WP_020734439.1|3407553_3408858_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227301	COG4966, PilW, Tfp pilus assembly protein PilW [Cell motility and secretion / Intracellular trafficking and secretion].	7.44418e-05
NC_021658.1|WP_049949484.1|3428772_3429429_-|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	5.65067e-29
NC_021658.1|WP_020734450.1|3420774_3421119_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	8.43713e-05
NC_021658.1|WP_063751977.1|3409456_3410185_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	4.51154e-11
NC_021658.1|WP_148314776.1|3422300_3422795_+|lamin-tail-domain-containing-protein	gnl|CDD|376421	pfam00932, LTD, Lamin Tail Domain. The lamin-tail domain (LTD), which has an immunoglobulin (Ig) fold, is found in Nuclear Lamins, Chlo1887 from Chloroflexus, and several bacterial proteins where it occurs with membrane associated hydrolases of the metallo-beta-lactamase,synaptojanin, and calcineurin-like phosphoesterase superfamilies.	9.0575e-14
NC_021658.1|WP_020734457.1|3429609_3430605_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.04929e-61
NC_021658.1|WP_020734445.1|3412334_3413183_-|MaoC-family-dehydratase-N-terminal-domain-containing-protein	gnl|CDD|178455	PLN02864, PLN02864, enoyl-CoA hydratase.	2.39304e-60
NC_021658.1|WP_044985756.1|3403296_3406947_-|hypothetical-protein	gnl|CDD|225953	COG3419, PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 [Cell motility and secretion / Intracellular trafficking and secretion].	2.32854e-13

Protein sequences

>NC_021658.1|WP_049949483.1|3414187_3416542_-|serine/threonine-protein-kinase
MKPSPAKSCPSCGERYDAGVLYCPRDGTPLASSRKSASLGAAERDPYVGLTLGGQIQVRHLIGIGSMGRVYRAFQAGIERDVAVKVLHRELSSNAELVSRFHREAKIASRLVHPNVVQVLMTGSIPATADARIGGELYLVMEHLDGISLLSALAAAGTAGESEALPLPRALHIILQVCDAVGEAHAQGIVHRDLKPENIMLVRRGEDPDYVKVLDFGIARLDWADKAMTTQAGLIFGTAKYISPEGAEGQRVGPPADVYSIATMLYQCLAGRAPFEGDSPVALLVQHTHAPPADLRSIARSSYVPAPIAEVVMQNLAKKPSDRAPDARALGRDLALAVRASGLDPDEIAAQPGLLRASAVMKLASKSRTKSLDLSPALAAKIGGIAAPTLESARVSDLDPLLPASEAALYGGPASPRHEEDPSSTSDEERSSSPRASGVERYSASSGERYSASGGDRYSASDGERSSSPRASGVERSSASDAERASSRASGVERSSFSSADFGGAPDEPARTAVGLGIDPARDSAPAPSTMQGVASAPPQLPRRAVIARATALLACAGAVGLVAFLGGRHLGAFGGKSAQDSLEGHIDRARDCMGRHAWDTPPGENVKDIIAQALARWPRDARLGALRRESAERIVADALGRKYAGDRPGAIRLAKLAIELHPELTTAQHLVAELSAPPKDAPEEPPPQVSPQSSGLRNAGPDRRPPPRRTAPDGDRGSPPGQPPAPGPRGAPAPPPASGGAGAPAKTGAAPPPGSDAPVLPPSPPPLPAEGSSPLPSSTGPWL
>NC_021658.1|WP_020734446.1|3413340_3414177_-|hypothetical-protein
MNRGGWYPTSRAPPNVRAGEGDRAAPPRRDGARSKRRAAGAAGAAALALLLSAAPGRADESRAARRAAAARERDRPYTMVEMSGGVMTLPGADVCPVLAPEACEQGETSVSFGIHNLYRWGDIGFGAGIFWAASLSTDAAHGASSLERDHSRRYFMLDGVFRYYALRTPKTEWWVGATVGGVVVNDSWSVEADRNPYSDTAYVGPRAATIGTEGVAAGLAIGGDWAFAENWSVGSHLRYSSWFLPEQRKISPTGDRASLSERVDMFNIGVLIAYRVAL
>NC_021658.1|WP_020734445.1|3412334_3413183_-|MaoC-family-dehydratase-N-terminal-domain-containing-protein
MPLNLSTVGHTTKPSAFTFTWKTLATYALGIGARREELEYLYEGVPGGMKVYPTFGVIPSQDAVFSALEAAGAELPLIVHGGQTLRVHRPLPTSGTLFTTATVSGIYDLKKFAQVIVETKTTLDDEPLFDTVWSIIVRGVGGFGGPRPPQSEPAASVPKDREPDWVVEQATAPEQALLYRLSGDENPLHADPEVAAKASFAQGPILHGLCTYGFAARAIIQKAAGGDASRLRAYGAQFRKPVWPGDTLITRGYMLEGGKVALVTSVKERPDPVLTSAWAEIG
>NC_021658.1|WP_020734444.1|3411567_3412284_-|peptidyl-prolyl-cis-trans-isomerase
MSKTTEKDRAKDDEDLDEDESTDEGNDDGEEEEAKATAIRGRGHAHDDDDDADDDGADPEDAYWWAPHAVLSALVLIGLLGFFGMFNKTPLARLAAPVAPEPDDHAHTAAAAPPAPAPTPRPAKSAQPPREMFGAKHLLVMYQGSRRAPATITRTKEEAKARATEAMKKAKADPSKFADIVKEYSDEPGADRRGGDLGKFPKGAMVPEFQAGLEKIKVGEVSDLVETPFGFHVILRTQ
>NC_021658.1|WP_044985757.1|3410262_3411447_+|hypothetical-protein
MRFPPERCSSRVPSAPSAPVACGERPRRFRAGSCALLAGALAAALSAGCSKKEEPMGAPPPPPPAAKPAACADGGGTISDAASAPFFPRTTGGFCLDPNGAAKTFGESAPLPLDSICDMFDGECEIYKGFGVRRVVEARYVSGAGGSATVDVHLSKFGSTEGAYGMFTKRTVGDGDPADEATPRQIDGGGAAAMGVGNAYLWRGQYLAEITYNDEALAEAALKSSSEKVLPGLVKEMGSKLPGEPSLPPAAAALPKDNMIPLGVRYETKDVLGVDGAGPGAFGYYKEVDKRYRVAAIVRADVDQAKDVLSTLAKLPGAVREKGIGDGSVRLMHKEGESPATEWIFARADKTVYGVGDEARVLRSGMTADEHAKLTLTKEEKSARLKKIVTAPAR
>NC_021658.1|WP_063751977.1|3409456_3410185_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MQIHGLARIAEGMRLAFAGHLVRPFPCSRPPLRDPDRPRASSPRERARRRRNGRGFTLPELLAVVVLIGILAAAASPSFVNGMRDRRVNRTAMEISGLYRLARYQAIGRGAAVLVRWTAATGQFEVRQARVQNIGAGSLIATSCRSIANWMDPALTDPVTTLQTEGIELAAVELRDPTAPDGAVRANADICFTPRGRTYVRYATSGDLVPLLGAVRVNVTNTRTGLVRSVFVPPNGVARLGL
>NC_021658.1|WP_020734440.1|3408854_3409460_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MSAARVRRAGRSGYTLIEVMAALGVLAIGATGVLALQKATLISNTNARNIAIANNIAMTWAERLRVDALQWNEPRRVPDLDGDTQWLRLTTASPFPAKVTPTRVDTLGAPSADVFGTDIHLGDSSEPAFCTHVRFRQFTDPATGTRRWESLIRAEIRVIWERNGNPINCAVDPIDVDQQPDRFGAVYLTTGVLRNTSEDRR
>NC_021658.1|WP_020734439.1|3407553_3408858_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MTTDRRISPARARASGQRGFTLVELLVAMAAGLVVSLAAFLLSKNATRFFQHEARASASHLAATVGLNRLAADLQRAAYLSTPNIRADPEVCQVPAEPPGLNVLAGIAIRRQGSVFEGGGELTQSADNDLYPDSIIIGGSLSSNELFEFRRISDATGALIVELNPNSAAVQRTLQRANGSGQGLSQIFAPNRILRVMVRGQTQFLYGVIQGTIVQGDPPNLIAITLKPTPGLPMLSGLGRCGVTPGGATGDGGWVNVVNRVRYNIRSLVGKETPYAPLVAPIAPAQTGDNGRTELVRVELDDQNNEIDETLELVAEYAVDLKFGISVAEESTDLSVTDPFIQRHSITATDNTEVYNVAAPLDQLSTAAPQRVRSVQVRLSTRTRAPDRDVGYPERSDGRRLRFLIPGIVGGATYARMRTLYADIALPNQAYVKW
>NC_021658.1|WP_020734438.1|3406963_3407560_-|hypothetical-protein
MVNASIARSRRRAHERGAAVFIVVLVITMLTAIGLFAANVATLSTIATGHERRMTQTHYLAEYAMQLALAEIEQNGGLDAIAATESSNCSISTEPCWVFYPHTFAAAEDLLELPAPDAPGSLGRANIAWIAKVEITDKIKPAIGNRAGSDQGGPNAVSADYCTVTMNARLIAWPNGAVMEAVGSQESMSVVADILCSK
>NC_021658.1|WP_044985756.1|3403296_3406947_-|hypothetical-protein
MRNLTKVLVTMGSAATVGLVAARARAQAMDVEPPLPNVLLLVDTSGSMEKTVAGGEPDCNPLTPPASEATKSRWTKLVESLTGPIPDFSCYAQPRTQSEFIDEFTIDGEPPYDANYYIPFHRLLSNGCTPTPHPTNNDVVGHRYDDAGIGCTFPYEAPNGLLDVYQDRIRFSLMTFDTLPDARTGLVGGVPNAQSGMRGMWSYFLEFQSGAGYPARGNPPECAVEDMEVGAKNPAAPLWEGPLIPFPTHDAPIDTVREKNLKIQKALLATRPYGATPLAGMLSDARDYILNDASLWEGQPLGPRDDPYISGGCRKTSIVLVSDGEPNLDLRPTCAQGPGPGPEGTGCPYEEPHVIAHSLNTHVNPNRRVRTYAVGFGLTTQARQELSDPTFDCARISSTDFLPAGRCDNATGAVRACCTLSRIAIEGGTDRGYFPDDANELSAVMSQIFARISANSTSRTLPVFAMATSTVNNGSDAAGVAYQFGSSFSPPADGSLWSGNLERKRYVCESVNGVMTTQLEDVDPGKGDDFAANVSSNDLARPRRFLTVIGDLDVAEQRVWSQRTIRPAAAAVDDLSDYTGTVTGSGAPAPAQAFADALSSAPRALGLNPSSGTVPSQCSGGLQAATAEVCAERIIEWETGEPMPANVPSRDGNELGSIYHSTPVVVGAPRDYIPDESYRLFAEQPAQANRPLVLYTATTDGQLHAFQVTAATATDPLKVDRVQNNELWSFLPPYVLPRLLDTFNQQSILLDGAPVVKNVVFERTSAQISEASASWSTVLLAGGGAGGGFYYALDVTNPTAPRFLWQLSTDEAGNPLFGASTPTPAIGMVEMEDRGQIREIAVAILPGGSAPLDASQPACNRKGTTHPLFHPTGSLSVRSSVRCWGSAGSGGPVGPARSLTIVRLETGEVLRTFRGLPSEAPSVLSTRTTEVDFDSPITGVPVPFPAGVGEVAERIYVGDADGTLWRVNLSSTDPDEWSVSLAWDAYSITGMGDAAASSQPIQTTPIVSTDPLGNTVVLFSTGDQESFTPGVETRVWSITERPHETSVRISENWVVPLTNGQRVTGPISLFNGCAYFATFTPVAPGTFACADGFGSIWGVDYLLGQAATPAAYPRGSGCLVEDPLEPPFEKQAPGTVVFGVAVTQKPTCTVTEEYTDVHFGTQTIIRQSTPPEYQLVFHTGAAGQEDAQGGETRTTTRTLQPPRKVVKIDSWATILE
>NC_021658.1|WP_020734450.1|3420774_3421119_-|helix-turn-helix-transcriptional-regulator
MAPEDIKKLRQELGCTARELAGALGIEQETVLAWEHGDLFPTKRFVGMMEELRRKGPEAIPRKKKRQTTASPLQLLSDPELWRLFRKLLAHPELRSAAMKLAETYPDPMDAPPS
>NC_021658.1|WP_148314776.1|3422300_3422795_+|lamin-tail-domain-containing-protein
MTREPMPHVIINEVLANPVGPEPGQEWVELYNDGDVPADLTGYVLADVGGETELPSISLAPGAYALVVNEGFVSDDELDPPAPPEALLLRVPKLGNHGLSNSGEPLKLMDGGGAVLSRSPAMPEPKAGMSLARVGPRAPDGSAGSFVTSWPTPGRVNIMNQEIP
>NC_021658.1|WP_063752129.1|3422995_3423625_+|helix-turn-helix-domain-containing-protein
MAGVREKLLTASDLAALCEVDLKTIHNWVDRGRIAHFRTPGRHLRFKAADVAEFLRAWGYSVPRELAKATSKSMMAIGTKDTMAHVARALGEGVPIRHANHPYDALIYAGADPADVYIIDVRAVSGDVDVTSLFEALHRANSQGTFVALSDEPISLPPFVGRIGRNDAQQLRAFLMPEAAAQPGAPLQASAGAASEEPPRSLAAGGSSR
>NC_021658.1|WP_020734452.1|3423898_3425239_-|PmbA-protein
MELAEQVVTRARKGGADVAEAIARSGSELTTKVRLGEPELVEEAVHKGLGMRIIKKQRVALTSTSDLTPRGLDRFVADALELADISQEDEFAGPADPELIAKGNFPALDLYDPSGGEVTAAQAIDLARRGEQAARDADPRITNSEGATFSRSAGAYALVLSGGFRGGVAGSYAQLVVSPVADDSDEKKRRGFYFTARRHLADLDAPDAVGREAARRTLRKLGARKVPTCEAPVVFDPDVARSMLGLLGSCLMGSAIWRKSSYLIGREGTRVASDLITVVDDPLIPRAPGSRPFDGEGLPSRRNVVVEQGILKTYLCDSYSGRKLKRSSTGSASRGAGGGVGPSTSNFILQPTATPAEEIVRSTPRGLYVTEMMGFGFNAVTGDFSRGAAGFWIENGELTYPVSEVTISLNLDELLQRIDAVGNDLDLRTATSSPTFRVSAMTIAGS
>NC_021658.1|WP_020734453.1|3425437_3426190_-|hypothetical-protein
MPAFVAPLVGFALGALLAWFSAAASHRPGALRAAEPRLASGAPDRPLALVALFAVLVFAPVCAYFLVFAPDWSFAYLVDTRRIPSAVDLVLLLLDAASVPAGFVAAQRFAASAGGRPTAQRSLRALAVFAGAPLAIALIAVLALSRRLALDGTYRQVEGDFGVHPITGGPLGYALLWMHTMLAAGFAVTVSALLRREPPGGAQKGEPPAGPRPRAVPSAPPPAAEPPRPASTRPQRRLGLGKGGRSNRPG
>NC_021658.1|WP_020734454.1|3426470_3427223_+|nickel-pincer-cofactor-biosynthesis-protein-LarB
MEPRLVREMLERVRTGELAVEEALEALRGLPFRDLGVATVDHHRALRQGVPEVIFGEGKTPEQIALIAQEISGAGQNVLVTRVDAAKGAAVASLLPAFRYVPLARTGTVEVAPTPKRAAGPVAVVTAGTSDVPVAEEAIETLRAVGLEAKRLYDVGVAGLHRFLHRVEELRKASAVIVVAGMEGALPSVVGGLVAAPVVAVPTAVGYGAALGGFTALFCMLTSCASGVAVVNIDSGFGAAMVVHRMLPKE
>NC_021658.1|WP_020734455.1|3427291_3428668_+|nickel-pincer-cofactor-biosynthesis-protein-LarC
MGHGHDHDHAHGHGHDHDHAHGHGHDHGHDHDHGHDHGHGHDHAHDHDHDHAHGHDHPRAPLLEEGAGAGKILFFDAFSGIAGDMTIAALLDLGVPLLVIERAVAALPIEGFHLHRGHAHRSGIVATSFDVHVEAPQPERTYGSIDAMLAAAPLDPPVAALARRIFRRLGEAEAAVHRIRLEDVHFHEVGAVDAIVDIVGAAAAIVHIGAEVVGSPLPMGRGFVKARHGILPLPPPAAVACLRGVPTYGVDLDAELVTPTGAAIIAALATRFERWPTFAPDRIGFGAGQRELPDRPNLLRVVLGTRSGGEESLGSASHVIVEANVDDLTGEVAGHAIEALFAAGALDAWAAPITMKKGRPALTIAALAAAPQADAVATALLRETTSIGLRKIPVARTERPRRITTVKTAYGAIRVKISEGPFGPPQVKPEFDDCAAAARTHGVPVREVVSAALAAAKG
>NC_021658.1|WP_049949484.1|3428772_3429429_-|thioredoxin
MNSPAMAVPEISEQEFEREVLRSELPVLIDFTATWCGPCKTVAPEVDAIARELEGKAKVVKIDIDKSKRIATMLRIQAVPTFMVFHRGRPAAAEQGVLNRKQLREMLEPFLPRAEGAIRAVELAQLIQQGQVVPVDTREANAYGRAHIPSAVHLPLEEIEGRLAELHMLPGAPVLYCRSGDKSKEMAAKLAEEGVPVAFLEGGFLSWEAEALPIERPD
>NC_021658.1|WP_020734457.1|3429609_3430605_-|ABC-transporter-permease
MTHAAAFLRRMIGSKRVAAGTVLLGVLALLAIFAELLAAPAPIARLGPDGPEILPAVTDAAELESLTEAELRVRFEVGVALWPPIRYGPEQRTDAGPNASPSLDHPLGTDFESRDLAARLIYGARTALGLSLSAVLVGMFLGVVLGGLAGTLRGFWNDGLVRLVETVDTFPAILVVAIVRAIEREPSALSLVLAVAFVRWAEIARLVRAEVLRASSEEYVMAARALGSTRLRVFYRHILPNALGPTIVSSVLGVASVVLLEAAISFLGMGAPTRVASWGETLGQAARHPSEIRLLVLPGLLLLATVGGSYLIADALRDAVDARTVRSRTPR
>NC_021658.1|WP_020734458.1|3430601_3431741_-|ABC-transporter-permease
MGLPRADEAADPAHAVAFWTRFWDDRGIEFRSPSVRSAVRRLVRYGSESRAAELLELDTFALQPVIAALQPPRDAAALEQARALVDVAAHITEIDDRIAPGEDLAEARACVTRWKSFWNVYRSDFEVFSGPARLAATVLETRYGKWALGAVTHRLGVAATGEPVLDELERRAPVTLTLVFGAIALAYAVAIPLGALSAASRGRRSDSAIAAAVLTLAVLPTAVAAVAAALLAGGAESLLLPTCLIALSLIAAPTRQQRAALVAVLTQDFIRAARARGAGAARAIAVHGLRNAVLPVVTLAMLEPPMALGGAFVVERVFELHGLGELTLLAVQARDVSWLMAISIGAAGIAALGVIVTDLAYVLVDPRLGPAVLSRRSGA

Crispr_ID: NC_021658_7

• CRISPR_ID: NC_021658_7
• CRISPR_location: 3465079-3465174
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_7

Consensus_repeat	Method
CCATCAGGACACGCCACCCGGCCACCAGGACA	CRISPRCasFinder

spacers of NC_021658_7

>7.1|3465111|32|NC_021658|CRISPRCasFinder
CGCCACCCGGCCATTCAGGACACGCCACCCGG

CRISPR arrays and Neighbor proteins around NC_021658_7

CRISPR arrays

The CRISPR arrays of NC_021658_7

>merge|NC_021658|7|3465079-3465174|CRISPRCasFinder
CCATCAGGACACGCCACCCGGCCACCAGGACACGCCACCCGGCCATTCAGGACACGCCACCCGGCCATCGGGACACGCCACCCGGCCATCAGGACA

>NC_021658|7|5|3465079-3465174|CRISPRCasFinder
CCATCAGGACACGCCACCCGGCCACCAGGACA	CGCCACCCGGCCATTCAGGACACGCCACCCGG
CCATCGGGACACGCCACCCGGCCATCAGGACA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020734483.1|3479118_3479535_+|VOC-family-protein	unknown	unknown	gnl|CDD|319942
NC_021658.1|WP_044985766.1|3467839_3469387_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_021658.1|WP_020734482.1|3478050_3478620_-|hypothetical-protein	unknown	unknown	gnl|CDD|225575
NC_021658.1|WP_187345915.1|3475980_3477162_+|hypothetical-protein	unknown	unknown	gnl|CDD|164795
NC_021658.1|WP_020734480.1|3471996_3475602_-|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|223736
NC_021658.1|WP_044985765.1|3459535_3460726_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_148313511.1|3451312_3452458_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734472.1|3453141_3454146_-|PEGA-domain-containing-protein	unknown	unknown	gnl|CDD|276809
NC_021658.1|WP_148314777.1|3452667_3453120_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734476.1|3462481_3463900_+|permease	unknown	unknown	gnl|CDD|341039
NC_021658.1|WP_044985767.1|3470167_3471667_-|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NC_021658.1|WP_044988082.1|3456771_3458163_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020734477.1|3463926_3464889_-|hypothetical-protein	unknown	unknown	gnl|CDD|237372
NC_021658.1|WP_020734478.1|3465345_3466203_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044985764.1|3454142_3456764_-|hypothetical-protein	unknown	unknown	gnl|CDD|368175
NC_021658.1|WP_020734474.1|3458503_3459535_-|hypothetical-protein	unknown	unknown	gnl|CDD|224513
NC_021658.1|WP_020734475.1|3460870_3462139_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734479.1|3469489_3470122_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734481.1|3477158_3477944_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949488.1|3466361_3467843_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_044985766.1|3467839_3469387_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.22418e-72
NC_021658.1|WP_187345915.1|3475980_3477162_+|hypothetical-protein	gnl|CDD|164795	PHA00370, III, attachment protein.	1.75078e-05
NC_021658.1|WP_020734480.1|3471996_3475602_-|HEAT-repeat-domain-containing-protein	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.4543e-23
NC_021658.1|WP_044985765.1|3459535_3460726_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	1.56081e-08
NC_021658.1|WP_020734472.1|3453141_3454146_-|PEGA-domain-containing-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.56732e-05
NC_021658.1|WP_020734482.1|3478050_3478620_-|hypothetical-protein	gnl|CDD|225575	COG3031, PulC, Type II secretory pathway, component PulC [Intracellular trafficking and secretion].	0.000265206
NC_021658.1|WP_020734476.1|3462481_3463900_+|permease	gnl|CDD|341039	cd17486, MFS_AmpG_like, AmpG and similar transporters of the Major Facilitator Superfamily. AmpG acts as an inner membrane permease in the beta-lactamase induction system and in peptidoglycan recycling. It transports meuropeptide from the periplasm into the cytosol in gram-negative bacteria, which is essential for the induction of the ampC encoding beta-lactamase. The AmpG family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.34085e-98
NC_021658.1|WP_044985767.1|3470167_3471667_-|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	8.11752e-11
NC_021658.1|WP_044988082.1|3456771_3458163_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.69576e-88
NC_021658.1|WP_020734477.1|3463926_3464889_-|hypothetical-protein	gnl|CDD|237372	PRK13386, fliH, flagellar assembly protein H; Provisional.	0.00436898
NC_021658.1|WP_020734483.1|3479118_3479535_+|VOC-family-protein	gnl|CDD|319942	cd08354, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.8108e-17
NC_021658.1|WP_044985764.1|3454142_3456764_-|hypothetical-protein	gnl|CDD|368175	pfam04885, Stig1, Stigma-specific protein, Stig1. This family represents the Stig1 cysteine rich plant protein. The STIG1 gene is developmentally regulated and expressed specifically in the stigmatic secretory zone.	4.48296e-14
NC_021658.1|WP_020734474.1|3458503_3459535_-|hypothetical-protein	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	2.81151e-13
NC_021658.1|WP_049949488.1|3466361_3467843_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	8.99239e-85

Protein sequences

>NC_021658.1|WP_020734477.1|3463926_3464889_-|hypothetical-protein
MGQYDIALRHIALRCGDELARGLTLAFAVDSVSWVETQLTALERRIDRVLELRGGGQRRLVQLEFIVAPGNDLALRMFEYAVLLVLSLRAAVDPGRGDGAIPPVESVAVLLSGRAAPWPLEGQFRTNWPESERFCGQSFRIEAVYQRKVAELMARPGVFWLVFTPLAVDATEGSIRQVVEEIRRREPRDEQRAELYAVMQVLAELAPWGHTWHKEIRMRVQELDQQSILASETLREVFEQGIEKGMEQGVEKGIEKGRRQGIEEMLRGVLARRLRRELNAAEQAAVANRASTLGDSQAAAAVFELDTEALLAWLLGPDAE
>NC_021658.1|WP_020734476.1|3462481_3463900_+|permease
MEAAVTSHKSVETAAPARAAPSDQGAEVARRGAPAGAPGAAAAPGAAVAPGAAAERAASRGLWISSTYFAEGLPYAIAHKVAGEFFTAAGASLQIIGLVSLYGLPWNLKFLWSPLVDLHGSARRWLVGAEIALAVILLGLAATAESGALGLVAALFGLVAVAAATHDIAVDGFYLQALDKDAQAAFSGLRVGAYRLALLAGALLVAFAGWASFGASFAVAAAALALLAGAHAAGLPRPAAAPAPGAPAAGAPAASGAAAASGAAAAPGVAAPGAAGLRRYVEPFRAFLRQPRIASSLAFILCYRAGDALMFAMSSPLLKDLGLDTAARGNVAGVGTVASIAGSTLGGVLIKRWGLARTIFPIALLQSLAILLYVALASLRPALPWIVALVTLEQLAAGVGTAVLVVFLMRRCVDGYKSSHFAIGSALMSVSATFAGSVSGYLAAGVGFTAFFAIAFAASIPGVVLSRWVPRE
>NC_021658.1|WP_020734475.1|3460870_3462139_-|hypothetical-protein
MNEYTRREEVRATFIASAILVLCIAVAVLRLVTVEGRLVPDPAARRQAEESEARIAPARACALAGEKLIVEIDLFKKAAKSARMPAPGEEPPAPPPVTKTRAQRNTPLPKPKEPDKQGAWASAQPLYKQVKTLAGCREATEALLGARVSAIPAWDAIVKAAAITPPGTAEAEQFEAAKQLLSLLADIPADKVAQATKDAEAAYKANAERDRERALTAMVREPLPQGVFSRRVAVSVGVGLTVCALLISYLGVRAASMRRLATLLPLRDAVRSGRPGMQAAEILKTAAAHNSGEPGIVIGAAIGGLSAALLAPKDADLFVAGVMAGLLIGLGGQWAFRLALGASRWRARATELAEVEKPAIPIVLVLSGVKPGLEPEFIQFLRSLPPADAAAAVEKLASQAEERILAAADAGAAFPQGKPPPG
>NC_021658.1|WP_044985765.1|3459535_3460726_-|hypothetical-protein
MKTPLQARRPPGRWALVSLLAATWWLAAPPAAAQDPAAANAGAPPEPPPAAQAAPPAVAAQDDGAPQDDGAPQDGAPAADGAGAPPSGGGGAAPESGPRADRSPARRDRPGATSSRATPSKKRRGDINPCMTPDPGWGVYDRWSRAPSIGQMIMPHKGGVTKRGGFDVIIHFHGHEALRKEFVKTADGAVLVGIDLGIGSGAYSSAFSAPYVFENLLDSIERAVAKKTGKKKVYIRKLGLSAWSAGYGAIEQILRQPAGKRVDALVLLDSLHAGYADEHQRKLKVAQIEPFIAFARRAAAGEAFMFMSHSSILPPGYASTAETASFIVQQLRGKPRGSSRRDVLGLDMIRRFDRGDFHLRGYTGDDKPDHCAHLGLMADVMRVHLKPRWKTPRGRR
>NC_021658.1|WP_020734474.1|3458503_3459535_-|hypothetical-protein
MGGIGVIINPRSRQNQSDPRAAVRLARALGDHGVVRTARTREDLARIAEDFRKLSIDVLGISGGDGTNHVTITGFLDVYEDEPLPPIAFLRGGTMNTVANAVGVPRGRPDGLLAGLIARYTDRGRHPLRWVERHVMHIGAHYGFIFGTGCVHGFIAEYNRSEERNAVWAAKVLARASAAVLLKTDTQVAARWEGRVHFDDGSAFPDRDYLAVAAGTVDQIGLGFRPFHRYDERPESFHMLGIHTSALGFVRKLRDIWRAQPMGEAHTFEKIAQRAVLEARSGVVRYVCDGDVHEHVGPLTVRIGPRVKILVEHKTGHRPVASRRTSHEVCARGARGERARRAR
>NC_021658.1|WP_044988082.1|3456771_3458163_-|protein-kinase
MIGGKYRLRYVLGEGGMGMVWLAHNDVLNIDVALKFIRREVTSTEATLRLQQEARAAARIDHPSIVRVLDFGESDHRDPYIVMEVLRGEQLVEAIERRKRFSPAAALRILLPIASALAAAHDRRIVHRDLKPENIFLVKNDRGDVIPKIVDFGIAKVWSETAGGDVTKAGTVLGSPDYMSPEQARGITDVDGQTDVWAFSVVLYETLTGQRPFLGGNYHDLVAAILVKDPVPITELGVGDAALWSIIERGLAKERAGRWRTMRDMGVALARWATENGVEEDVTGTSLAVHWLSDGGQRRLSERPAARPPRSGPDVETLDREEREEIALPPSGRRRSAVLALAAVAAVVAIGLALFTLRGVTARDGGADPPPAATSAAPRDLPSPAAAAAPTTAGQDAGNQAHPAPARSAGAPAAAREPRREPTDGGAGPSASPRNAGARRSAAPRTTSKTPSAALPVPARPNF
>NC_021658.1|WP_044985764.1|3454142_3456764_-|hypothetical-protein
MPMNVRPARAARHREPTLGARWPLLLALAVLTGACSLLADSALSDKPSEGGAGAPSSTSTGGCAPDCPADACCGGACVDLSQDPGHCGACGNACGAGESCCEGECTSVLNDPSNCGACGAACLNTLCVGGHCSSECVFGFDNCDGNIVTNGCEVDLTSDPERCGGCSLRCPSGAICDAGECACAPPLLDCDALSDTGCETDGSSNPAHCGACGVTCGPNMECQAGVCGCQAGYADCNLSPDDGCEASLGTTESCRACGDACSDGMACDLVGGCSCTNGLLDCDGLPGCESIVTDPATCGACGVQCPADTPRCDGTACVVTCAPGLTACGLSCVDTQTSPRHCGACDVVAGPHQHCEAGALACDADFADCDPSAPGCESDLARDPQHCGACGTACKPGAACVAGVCACGGFTPHDCGADCRACCSDADCSDGDGCTTDVCEAGGTACRSTGCAAGEQCCSLVACRQCCTSADCSGGEICSGGACIPPCGSGLVACDGACVSLGSVEHCGACGNACLSGRECRDGECTPPRVAMAAAGAPMPRQMAAAAWIGDALFVWGGRTASRDVNDGALYDPARDAWSPLGTAGAPSARVLAGAAWTGSRVLVWGGGAFGSTAGLATGAAYDPAVRTWRAMSTTGAPAARRSPIAVWTGTRLLIWGGAAGGAPVGGGALYDPVADAWSPVSSVGAAPARDGVAWAWSGAELYLFGGRAGDATTGDGYAYNPTTDAWRALPGAGAPSPRADAFAVWMGGRLLVWGGVDKDDRDLDDGAIYDPAAGTWAAVDDKDAPSRRSRSERRTGWTAWTGTRALIAGGRSDAMSKKDGKLYDPAAGWGASLAVANKQHSYGVGVWTGTELILWSGFDGFSLLADGERFRP
>NC_021658.1|WP_020734472.1|3453141_3454146_-|PEGA-domain-containing-protein
MTPRRTRALAGPLALFIAAAGLLAAPAPAAAQSAADVAVAREIFIEGSEFAKQGRWEEARERYERSLAIKRAPITLYSLGVAQQQTGQLVEALESFRAFLVEPSAPATKEYEKLARQAVQELERHVAGLDLRLSPDDVAGVVVKIDGIEVPAAALDRPRPVNPGNHVVTVSAPGYREARRSVAAAPGSRVVVMLTLERDAPAPGASTPGASAGPRAPSAGALPGGAPPRAAPDAATVRVVPIVLLAGGLTTVAAGVAIGLLGVASASDAPTRDGDAADAARAQALAGDIVAGAGLLAAGAGVLVLVLDRGPAGAPRRQAPPRAAVGPLRLTVRF
>NC_021658.1|WP_148314777.1|3452667_3453120_+|hypothetical-protein
MHGCSLEAYLEEPGLTEGQRRRLRLFQTVEDAVSDRVEQLCTCSELEVTDAAILVVSPAARRLLFRSAAAAGAEPPAASVILGHRARLHAFLHAALPPTDEAPFDPYADLLAPSPPQCVRVLILDEDSLTVLNYGAFVVVTLDRGEMPAA
>NC_021658.1|WP_148313511.1|3451312_3452458_+|hypothetical-protein
MHTRWRGVMASMLAAVALSGLAGCDGDKSKAQVAVDAGALDAGPALPVVGGKLGAELAAAASGGPESRPAPGGAKDAPPENGVFSPQAAAAALPKDVPYKIEVIDAGSEPRAQLAAKVDPKSEQKVAMTLGLRMGGPQGLPNLELGLSIKADKPADKPKEGAPAPAAPTTVTAKITSATLASMSIGGPPKELADALAKLKGSALRYDLSPANVVSNQKPELAKDADPGLQPLLAALGEALTLLTPPLPDKPVGAGAYWMVTDRAVVSGAQLPVLRYRVFKIEKVEGDVVSLSVDTRQYAEGADLKLPGPNGDVTLTIDRLDSAGKGTLTWSPSSYAPGTADASQRLQALLVPPGASGQQAAQQRSVAQVELTAKIAPPAAQ
>NC_021658.1|WP_020734478.1|3465345_3466203_+|hypothetical-protein
MAKKGKDYDRWVKAAAEQARTDNPLSLPYDVAVREAVAAAAFVKKYWEPDGERPGLKRVKSRLPASSSEELLSIVHAVQEAQTRLLLIIDPAVTDLGERARFLVDELESALEFLLDDDVDEPADAQLARLKEFHAQDGQRSSALSQALRDYAGLAESLEDRLVEADEEFDVRLIAEARKLAEDLQRRTLEAIPERATSAAATTIRNQLLHLMLERVGAIRKTAAHVFRRHPEIVREVTSAYERRRRAASRREKARKAAGSKPVENRQGAVPPPAAPASPAGAPPS
>NC_021658.1|WP_049949488.1|3466361_3467843_+|insulinase-family-protein
MQTRARHPPLPRSTGPILAAVAAAFSLSGPKAAPAAPPEAAAPKPAPGAPTAASPPRKLDVPFTKYALENGLTVILHEDHALPMVALNLMVKVGSRFEEPGRTGFAHLFEHLMFMGTRRVPTKQFDAWMEAEGGWNNAWTSEDRTAYHEVAPAHALPLLLWLEADRFASLADSMDTAKLNTQRDVVRNERRQTSENEPYGKVELLLPSLMYPKGHPYHHPVIGSHEDLQAATVDDVTAFFRRWYVPNNVSLVVAGDFDPQKARDTIERYFGGIPGRPVPAATAPPPVKLSGVVRQTIEDDVNLPKVVMAWHSPARFAPGDAELDLLATALEQGKASRLYKALVYDKALAQEVSALQSSGDLGSTFIVEAIARPGVALEKLEGAIDAELARVRDESLSREELDRAKNQYETAFVTALESVAGRASMLNRYETWTGQPGFVEQDLKRYRDATAASLQAVAKSTLDPNARVIVRVVPKGSDEAKKGSGETKKAVTK
>NC_021658.1|WP_044985766.1|3467839_3469387_+|insulinase-family-protein
MRARNAGALIALLAAAVGCEPKAPAQSPARAEAPQKAPPAAAAQPADPLGPKPELPKPQPFTPPAPVVLDGPNGIKVWLLERHTLPIVAVSVAVASGSADDPKGAAGLAHITADMLDEGAGQRSAVELSSAINDLGATLAVGARADGSVATLSVLKKNFDKAFSLLADVVARPRFEAKEWKRVSELWQNDLRKRGDDPTRVSALVSTAALYGPGTPYGHPVEGLLADAKSIGLPAVKAFYKAAWRPDGAVISVVGDITRDEVMQAIARDLGAWSGKGAPAGAAPADKGAPAAPAAAPAWKPPRLVLVDRPGAPQSVIAVVRAGVAASDPRRPLLQLINTALGGSFTSRLNQNLREDHGWSYGAASAFSETKRPGAFVARASVVAEATGPALKEMLSELAKMADSGLTRDELAKVQAQDRADLVSAYETVNRTALRLGTLARLSLPETFDGAASQARQQATLAGLAELARAVDPKGATLVVVGPRQEILPQLQAIGLGEPEAWDVEGQPIQPKKTP
>NC_021658.1|WP_020734479.1|3469489_3470122_-|hypothetical-protein
MTFSADFVKLRSLGLWSFLLVAAPLASSGCIIVDEDGHHGGHQHDDGDGWEDDDDDNEPPPPADEPRLVAIDTDAALSSEPGEGVGIFVEYAAGGTWRLWTTCDTNSSKVVCSFDLYASVDTSSELFDIVGTDLEKSDATRLADDGIAYLHAETGSDIDAMTFTTTEGAIVRLEAYLDGVQEPRYVYWFGDGVLHEGAPTNPIDFEPTSP
>NC_021658.1|WP_044985767.1|3470167_3471667_-|hypothetical-protein
MHPMPLPPSAPPKRPAPAASGITRALRRLAGALPLLAALVAAPSSAAAQGLPQGYTTDEPSAAGETAASRSAETRPVQAEVGVSAEIAVDEYEDTDPSALIEFQEPLAPYGTWIDHASYGRVWVPSAVVVGPGFAPYQTAGRWELADDGEWLWVSDYEWGHIPFHYGRWVWLPVHGWAWIPGRAYAPAWVVWRVGDDGYIGWAPMPPTYTWSSGVAVSLWTVPPAAYVFCPTTYVFHHHVHRHVVRDREVVRRIAAHSHPYRPARPTVSRTGRDDVRPDGRRGAGHAGPSHSIRPGSYRPASPSLAEARVPSSAAPKARGKADPRALAYARKSTAPSARLAPPSSRRISAPPAPPAPAGARRAAPSLRTPRSHDDAPASVARPGLPGRGFSGAGAPHRASRATVAPPSAVPAPAPRVAPSPRVAPSPRVVTAPRVDASPSAPRAVPQRSAPAPTPQLSAPVARPRALPSAPAPRPRIHIPSGPAPGRAAPASPARPRSR
>NC_021658.1|WP_020734480.1|3471996_3475602_-|HEAT-repeat-domain-containing-protein
MDPTDAAPAEPSAKGRAAAPEPQRSGQPSARPDGAPAPGSAPSVRPTSSRPSRLPPSGAPPSTDTAVLGVTLTRVELHRSALLFCLLFLAALIFVVGRSARDALFLTRFPVTWIAPMWIVYGAASAVAALAYDRIARRLPRARLCVAFALFGAITFALLRVLIGQEVRGAILVFYIWSEIIANFTAVLVWAVAQDLHDARSAKRLFGLIGSGRVVGTVACGFGTGLVVTWIGTENLLFVLIAALLAMASLTTALARRHPLERPPSGDDERIQARLPRMEVWRSRYALTIALLTLLLFTVLTVGDYQFKAIALTAYPDRDDLARFMAHLYGAVGVIGLLVQLGATPAVLRRHGVLGGLLAMPAAFTASTAALVATPSLAFASIMKLSDNALQFTIYDATMQLLFFPFPPALRERVRTLVSAIAKPLGYGLGALLLLALAPTAATGPALVEEAARLGLYCLPLCVATIALIPLVRRGYFDAMRRTLMRRQIGPDSVVYGPQTRAILQEALYSRAMTQVLFAVDQLRQLDPALVREAVPALARHGSARVRALAVRLAAELEHEEGAEIARAAIRDRNTAVRVAAVDALAALLREDAHDELLALARESDAPRGASAGAPGDDELRAAAIAALLRYCGLDGMLEGAPRLRALLESPSPRDRVAAARILGMVGHASLQRALARLIGDPDPAVRRAAVRSSSSVADPRLLPLLADALAERALASAAARAIEALGDAAIPELAARLDDDGTPRAARLALPRVLARLSSHGALDALLAQIDHPNEALRQKVLASASRLRLALRAPPAPLRRIRACIDDETVEHVRTREAYIAARPRVAGPLLDQHLLRRLRKGIIRVLRLCELAYPREVVALVRTHVFGPDPALRANAFEVLESLLDRPLRERLVSLVERLLALSAEFPRRPMPPEADAVAWIRRELVRGEPYSAALALDAVARRAISGAAADALAATWDPDPLVREAAAIAIAVTAPPGAAERLAALRADEDPAVARYARYWAVTGGTGIDPEDEMYTTIEKVLFLQRVPLFSRVAGDDLVALARGSLVVSLARGDVIFRQGEPGGALYSIISGEVSLTLDGREIARLGANDVFGEMSLFDSEPRGSTAVVTEDAELLRVSAEDFHEAVRETAEIADAVIRVLNRRLREADRKLADAHARLSLLPKPPQLPSRAPPPLPSRAPPPSDEEAPALDDSDLD
>NC_021658.1|WP_187345915.1|3475980_3477162_+|hypothetical-protein
MDTTRTLVRLRPRGRRHLARMCAAALAAAALAGGARRADATVTISTDVDRTGDRRQDAQNPLWISREDCLTDNDLRFTVTLRDFSTSQTLEVWVSESQDCTLYSNRDTGTRCRKVTAVSPLRETMDIELSSKEIAAALGAEECEGTRSSTGAVSVTMYFMRLESLDEDEPDHAKWESTKLDLQGPKPPTEVEAHPGDGRLLVDFKQNEDEDVEGYYLYCDGGGQSSPGAGGAGAGGGDDGAGAAGGGSGGGATGGGSSGCGASRLVPGEVPATALRCGKVGKANRGEAAKFEDGAAIANGTSYVVGVAAYDLVGNAGPLSELSCATPVEVDGFFEKYREAGGQAGGGFCSVGGPVGAGRWVSAPLGVVVAGAALGLWRRGRRLRARSIKQESQ
>NC_021658.1|WP_020734481.1|3477158_3477944_+|hypothetical-protein
MNRHLRHLAAASLAGGAALLVVSAAGAQTRSDWRQHDRARILREERYASPQSFAFELRFAPYSPEIDEEFSGAGPYEGTFGDGAQFYFGMELDWLPLRIPYVGAIGPGLGWGYTSTSAKAFEAGSATRAEAEETSLTVMPMHVSAVLRGDELMRRTGVPIVPYAKAGLGMGLWFTSSGPGTADVDGVRGEGITWGTHLALGAMLALNWMDRRASSQLDETTGINHTYFFGEWMYANLDGLGSSPQMHVGTSTWVLGLALDM
>NC_021658.1|WP_020734482.1|3478050_3478620_-|hypothetical-protein
MLGAYLSLSALAGCGGQQAAAPAAAPAKQGASAAPAKQAAPAGQLARADVDRALLQGPPWILRRVPVEEVIRAGAFIGWKILALPADWSSIELKPGDVVTQVNGTTLERPDDLFAAYRALASASELKIAYEREGTARELAMPIFGPPSPETVKALESDSPPRRPATTRPRGTTVIEEDDGRTPLDDGAP
>NC_021658.1|WP_020734483.1|3479118_3479535_+|VOC-family-protein
MGETLPSLSVHHLAVVVRDLERAEAFYAGVLGLPVVRRWTDEAGAPRSVWLGLGGGAFLAVERAAAAGPTRSDEAPGWHCVALGIAPSEREAWRRRLAAAGVAVERESAYTMYARDPEGNLVALSHYPEPQVPRLDAG

Crispr_ID: NC_021658_8

• CRISPR_ID: NC_021658_8
• CRISPR_location: 3493308-3493398
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_8

Consensus_repeat	Method
TCGCGCCCGGCCGGCGGCGCCTGGGCGG	CRISPRCasFinder

spacers of NC_021658_8

>8.1|3493336|35|NC_021658|CRISPRCasFinder
GCGGCGCCTCGGCGGACGGCGCGGCCGGCAGCGCA

CRISPR arrays and Neighbor proteins around NC_021658_8

CRISPR arrays

The CRISPR arrays of NC_021658_8

>merge|NC_021658|8|3493308-3493398|CRISPRCasFinder
TCGCGCCCGGCCGGCGGCGCCTGGGCGGGCGGCGCCTCGGCGGACGGCGCGGCCGGCAGCGCATCGCGCCCGGCCGGCGGCGCCTCGGCGG

>NC_021658|8|6|3493308-3493398|CRISPRCasFinder
TCGCGCCCGGCCGGCGGCGCCTGGGCGG	GCGGCGCCTCGGCGGACGGCGCGGCCGGCAGCGCA
TCGCGCCCGGCCGGCGGCGCCTCGGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020734491.1|3490334_3490841_-|dual-specificity-protein-phosphatase-family-protein	unknown	unknown	gnl|CDD|350355
NC_021658.1|WP_044985771.1|3494963_3496472_-|hypothetical-protein	unknown	unknown	gnl|CDD|366506
NC_021658.1|WP_148314780.1|3503293_3504388_-|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|223717
NC_021658.1|WP_020734497.1|3501273_3502680_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239492
NC_021658.1|WP_080682096.1|3483022_3485779_+|N-6-DNA-methylase	unknown	unknown	gnl|CDD|274377
NC_021658.1|WP_020734501.1|3506272_3506644_+|EamA-family-transporter	unknown	unknown	gnl|CDD|224987
NC_021658.1|WP_080682095.1|3480953_3481241_+|addiction-module-protein	unknown	unknown	gnl|CDD|378247
NC_021658.1|WP_148314778.1|3482164_3482638_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044985770.1|3481724_3482066_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734499.1|3504402_3504996_-|isoprenylcysteine-carboxyl-methyltransferase-family-protein	unknown	unknown	gnl|CDD|224669
NC_021658.1|WP_020734489.1|3488826_3489009_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187345916.1|3479735_3480716_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734495.1|3497296_3499900_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|274782
NC_021658.1|WP_020734487.1|3486947_3488048_-|IS1-family-transposase	unknown	unknown	gnl|CDD|236090
NC_021658.1|WP_044988092.1|3491005_3493276_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NC_021658.1|WP_020734500.1|3504989_3506066_-|type-III-polyketide-synthase	unknown	unknown	gnl|CDD|225958
NC_021658.1|WP_148313513.1|3485766_3486861_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|225212
NC_021658.1|WP_044985772.1|3499945_3500992_-|hypothetical-protein	unknown	unknown	gnl|CDD|224279
NC_021658.1|WP_020734493.1|3493715_3494810_-|DUF2252-family-protein	unknown	unknown	gnl|CDD|313268
NC_021658.1|WP_148314779.1|3496832_3497300_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379171

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020734491.1|3490334_3490841_-|dual-specificity-protein-phosphatase-family-protein	gnl|CDD|350355	cd14505, CDKN3-like, cyclin-dependent kinase inhibitor 3 and similar proteins. This family is composed of eukaryotic cyclin-dependent kinase inhibitor 3 (CDKN3) and related archaeal and bacterial proteins. CDKN3 is also known as kinase-associated phosphatase (KAP), CDK2-associated dual-specificity phosphatase, cyclin-dependent kinase interactor 1 (CDI1), or cyclin-dependent kinase-interacting protein 2 (CIP2). It has been characterized as dual-specificity phosphatase, which function as a protein-serine/threonine phosphatase (EC 3.1.3.16) and protein-tyrosine-phosphatase (EC 3.1.3.48). It dephosphorylates CDK2 at a threonine residue in a cyclin-dependent manner, resulting in the inhibition of G1/S cell cycle progression. It also interacts with CDK1 and controls progression through mitosis by dephosphorylating CDC2. CDKN3 may also function as a tumor suppressor; its loss of function was found in a variety of cancers including glioblastoma and hepatocellular carcinoma. However, it has also been found over-expressed in many cancers such as breast, cervical, lung and prostate cancers, and may also have an oncogenic function.	8.73369e-41
NC_021658.1|WP_044985771.1|3494963_3496472_-|hypothetical-protein	gnl|CDD|366506	pfam01186, Lysyl_oxidase, Lysyl oxidase.	3.04481e-50
NC_021658.1|WP_148314780.1|3503293_3504388_-|FAD-dependent-monooxygenase	gnl|CDD|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	6.70127e-38
NC_021658.1|WP_020734497.1|3501273_3502680_-|phosphatase-PAP2-family-protein	gnl|CDD|239492	cd03398, PAP2_haloperoxidase, PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen peroxide forming dioxygen. They are likely to participate in the biosynthesis of halogenated natural products, such as volatile halogenated hydrocarbons, chiral halogenated terpenes, acetogenins and indoles.	5.1398e-64
NC_021658.1|WP_080682096.1|3483022_3485779_+|N-6-DNA-methylase	gnl|CDD|274377	TIGR02987, m6_adenine_and_m5_cytosine_DNA_methyltransferase, type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family. Members of this family are the m6-adenine DNA methyltransferase protein, or domain of a fusion protein that also carries m5 cytosine methyltransferase activity, of type II restriction systems of the Alw26I/Eco31I/Esp3I family. A methyltransferase of this family is alway accompanied by a type II restriction endonuclease from the Alw26I/Eco31I/Esp3I family (TIGR02986) and by an adenine-specific modification methyltransferase. Members of this family are unusual in that regions of similarity to homologs outside this family are circularly permuted. [DNA metabolism, Restriction/modification].	0.0001806
NC_021658.1|WP_020734501.1|3506272_3506644_+|EamA-family-transporter	gnl|CDD|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	1.92396e-07
NC_021658.1|WP_080682095.1|3480953_3481241_+|addiction-module-protein	gnl|CDD|378247	pfam09720, Unstab_antitox, Putative addiction module component. This entry defines several short bacterial proteins, typically about 75 amino acids long, which are always found as part of a pair (at least) of small genes. The other protein in the pair always belongs to a family of plasmid stabilisation proteins (IPR007712). It is likely that this protein and its partner comprise some form of addiction module - a pair of genes consisting of a stable toxin and an unstable antitoxin which mediate programmed cell death - although these gene-pairs are usually found on the bacterial main chromosome.	5.14023e-10
NC_021658.1|WP_020734487.1|3486947_3488048_-|IS1-family-transposase	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000197229
NC_021658.1|WP_020734499.1|3504402_3504996_-|isoprenylcysteine-carboxyl-methyltransferase-family-protein	gnl|CDD|224669	COG1755, COG1755, Uncharacterized protein conserved in bacteria [Function unknown].	1.48933e-56
NC_021658.1|WP_020734500.1|3504989_3506066_-|type-III-polyketide-synthase	gnl|CDD|225958	COG3424, BcsA, Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport, and catabolism].	5.18604e-124
NC_021658.1|WP_020734495.1|3497296_3499900_+|VWA-domain-containing-protein	gnl|CDD|274782	TIGR03788, marine_srt_targ, marine proteobacterial sortase target protein. Members of this protein family are restricted to the Proteobacteria. Each contains a C-terminal sortase-recognition motif, transmembrane domain, and basic residues cluster at the the C-terminus, and is encoded adjacent to a sortase gene. This protein is frequently the only sortase target in its genome, which is as unusual its occurrence in Gram-negative rather than Gram-positive genomes. Many bacteria with this system are marine. In addition to the LPXTG signal, members carry a vault protein inter-alpha-trypsin inhibitor domain (pfam08487) and a von Willebrand factor type A domain (pfam00092).	5.89091e-109
NC_021658.1|WP_044988092.1|3491005_3493276_-|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	1.26275e-20
NC_021658.1|WP_148313513.1|3485766_3486861_+|MBL-fold-metallo-hydrolase	gnl|CDD|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	2.58055e-21
NC_021658.1|WP_044985772.1|3499945_3500992_-|hypothetical-protein	gnl|CDD|224279	COG1360, MotB, Flagellar motor protein [Cell motility and secretion].	2.85035e-08
NC_021658.1|WP_020734493.1|3493715_3494810_-|DUF2252-family-protein	gnl|CDD|313268	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252). This domain, found in various hypothetical bacterial proteins, has no known function.	0.000764107
NC_021658.1|WP_148314779.1|3496832_3497300_+|MerR-family-transcriptional-regulator	gnl|CDD|379171	pfam13411, MerR_1, MerR HTH family regulatory protein.	6.08558e-15

Protein sequences

>NC_021658.1|WP_044988092.1|3491005_3493276_-|TonB-dependent-receptor
MSTEPPRDAPKDALVPPTPLTPLGADYPAGAHGDALVRLVLTVNADGTVRAAVAEEGQEPFASAAVAAATSFRFAPATRNGAPVAAKIRVEVRFTEAAPPDASAPAAAPPPAPGGGPARAPAPPPGAPRSLEVTVHGEQQAPGVSSLSRGEVRIVPGAFGDPFRAIEMLPGVTPLVTGLPFFYVRGSPPGNVGYFLDGVRVPYLYHLGLGPSVVHPGIVDRVDLYPGGYPARHGRYAGGIVAGETTPPLPYWHGEGMLRLVDVGGLVEGPFADGRGVALVGGRYSYTALLLSLAAPEVALDYWDYQARLSYQVAPQGRVSLFAFGAHDFLGEESDGETTTLFDTTFHRIDLRYDHAYGQGSALRGALTLGHDETGIEGGQKALTRSLGARVTLAHRLRDETVIRAGIDAVVDDNVLDLGTDVGDSPGGVGPDGDDDDDVSVGDLLLSRVDFTTGGYIEADIAITPRLRITPGLRLDLYHSDGAVALGVDPRLSARLSLGRGVTFVQAHGLASQLPSFVVPIPGVRPRLDDGLQRSFQSSAGLELALPADIDATVSVFHNAFFNMTDALGAAGFQSVDEAFTLRALGAATGVELSAHRRLTKRIGGFASYTLSRSTRSIGRSREVTSVDRTHVANAALTYDFGRGYRAGGRFVFYSGLPQRVGGVTLPPGSGVPGGLGSAAGAEPRWERLPPFFRLDVRLEKRWSIGKSGWLAVVLDVLNATMSKENMPRMCDGFGPCEPTEFGPVTVPSLGLEGGF
>NC_021658.1|WP_020734491.1|3490334_3490841_-|dual-specificity-protein-phosphatase-family-protein
MRVDYMPPAMTGLAAGIGMMAAPGRGRPLVEDLDELHHLHGVSLLVSLVSEHELELLGIQDLAERATERGIVVLRWPFGDFSVPSDAAALHAPVDRILDTAARGRAAVIHCWAGLGRTGLVAAACLVKRGLTPVDAIAAVRRCRPGAIENSDQEEAIGDFARTLGRST
>NC_021658.1|WP_020734489.1|3488826_3489009_-|hypothetical-protein
MAFELHDAGVALMRQNLRRRLPEASEEDIDERLADWLRERPGAEFGDAEGRPVPWPRRAP
>NC_021658.1|WP_020734487.1|3486947_3488048_-|IS1-family-transposase
MPAPLPLETRVRIASALVEGNSLRATARMVDAARGTVLDFALRLGEGCIRLHGRKVRGLAAHVIQMDEMWSFVQKKQARVTENDPAEHRDAYLYVALDANTKLAISYHVGKRDGENTEAFVKDLRARLTVVPHVTTDGWQPYIEAMFANFRGSADYGQCVKNYRGGAQRSPDHRYEPPRDPFMTKTPIFGAPKDELISTSYVERFNLQTRHTVGRTRRLCLAFSKTLRGHRAAIGLGIAAYNWVRVHGTLGTTPAVAAGLAERPWTLTELVTAALAEEETAPPVAQPLKLEPRTGEAPAPARELPGGRGWLRLVSGRSAPSASATPQPPPLAPVAVPASEPEPPPSEPPPAPKPRRMVQLSLFGDN
>NC_021658.1|WP_148313513.1|3485766_3486861_+|MBL-fold-metallo-hydrolase
MEAVEQLSLHLLDVGKGDAIVIDFPDGSFGLVDTGPSSRGEGVTEWLDQRAQRGKFRFAAITHWDTDHAAGMPGILRRYKPIRFYHPADELPLLEKLASSGDSTNPAALAEEIRRARDKDTIEACLFARDRLDTPEGVDLIALSPDSHVKDELYEAIRCGASWHQVRKLRNRLSVALWLRFAGVKLLLTGEVEAIQYKRMSDLFRAKNEPLHERYGSPQASWIKLSHHGAEGNNPPSLFQYFATQNVIASASAGGANGHPHPVVLHLVASRGGQAMCTRLGQGCGHIQRHQLDPNPMSWIANVSLKQLPNPQQRCYGDVSVKIVRDAAGSTTCQVRGSRTQANCPYGGPSDGEAKLIVTLRPRP
>NC_021658.1|WP_080682096.1|3483022_3485779_+|N-6-DNA-methylase
MLTTDAVRRTQRALSDPSPDRCFQALEALGWSDGDATVVWSPERFGLGQCHLGAYPTGASVTRETAPQPTADSEWWKKPYYGDYRWGLLFDHGRIRWCDLLGQKQCTVLQQDLTAEVLQGLTPESFASQGQLELLGVQASPLPNHRGKRAADYFSSMMESWFEDYLAASGADEDSEAKERFTRIISAFILLRTIEDVNRLDWLMPGALRSAARKGERALRELLGRAAKELNSRVLHGIADLLPATSRVRNLVEAFYQDQEDVRFSTLEADPVGAFYQNLLGTRYDVRPPINLNLFGENNAIVPDRSARKRSGAYFTPREYADLLATRLVLPAARNARTKDELPIVMDLAAGSGQLLCAALRQIFSLPRWRNPEVAIHVLERCIWAVDDDKNAPQFTALNVLRTVVQFVPDILGSGLKFPSLEKNVRKGNALQKTTLEELPDADVVLLNPPFHGAKRWREWMPPEGALEDVESLAGKAHSAFAFCLAGLTKLRAGGDLGILMTSQPILGDQSRAAREAVGRHFRIETVVINEVANVLDREKSYLSVVLGHKAYDVDRPGTQVISVVGGKGADIGALAAGAWSERSNSHAALVMLSDERPWDWTGQEAITSRQSAMVMRAEGHQSQIPRVRLSDLLGEEIHQPVSCAPKPWERELFLFRMTRPDVLRHEATHQEIRGTSASLRRVSIPNLLRSVPPFLEPFAGRSGELRVFFPGDGSPDGILWRGLRRSDPVGYKIAKLISRIVLDTPPKDLNDDALAFQEDVKRGILRFSWNRGYTSDSRALLLLSRSPKLPTGKKHELIWPCWIDPSGSAVPLGGSWVRVSKIEWAIAIGVMLNVPDAVMTILRSAPKRDETTEPTLRDKNAWLVPDLRDARCSRILRDLEQAYAAYQRACKSIQRGEALKCPELAHLLELGGELWRL
>NC_021658.1|WP_148314778.1|3482164_3482638_+|hypothetical-protein
MRATAQVKGFLLQRGVSLGNAQDVALECAFIAYRSVAKGTLALPDDASAYDQKLAAYMRTVAWRLLRNHKRAGDIFVRHDREPGTELLVSRTYDVEPALELASELAAEPPKARRFLLAMLETGEPCVAAVAAGMTKHAGKWTMRSTRARAAKRLAAV
>NC_021658.1|WP_044985770.1|3481724_3482066_+|hypothetical-protein
MLTVVRSPSGEQEGGGAPARRRRPRSPMLRLTDAERMRLRAAIRNLRALYGTWACLAEVMGVSAGTLQQLASGNGGSHAMALRAAKVAGTTLERILGRPAAAERCPHCGRGAS
>NC_021658.1|WP_080682095.1|3480953_3481241_+|addiction-module-protein
MLKDFAGLGGLVRAAALIPDSLPAEELLDQAMKLPESERRVLALRLLESVGDESSEEVDRAWVEEARRRLDDIRAGRSQPVAWEDARRRIFARLR
>NC_021658.1|WP_187345916.1|3479735_3480716_+|hypothetical-protein
MPRSTSDSVSPDGPVSLVLPFGAMGLVGGWLTADSFHLPDRSVHCLLAGVTPVVAGLLGHYMTSRIGGVGSAGAAAPGAAAGWADRPGGASGPGRWTRRGPIAASLLSLWAIVVAGVVNGMTVGLVLGPVGMLVGAPFGAVFSLPFVPALAVVLLAANRVGRARAGSVVAQADRRAVWSATAAVTAAAALAAPALFGRPAVPEVGLAVAAVGLAVVGALFVIDAVALAKVLTLPLPRRLIGAEEAGEGGAGTTGIMGTGERVDFGFGDEVRVEVVQPTHAYRGAPQVARVVRGNRERAVGALRAGLARGGIALAIGAALWGGPWTT
>NC_021658.1|WP_020734493.1|3493715_3494810_-|DUF2252-family-protein
MRPIRDSDLPPVKELTRAFFRAVNPHVEPVEFEEKWQAALRSPMRFMRSFPQAWHVDLLDVPRARVPGGRCLCFGDAHPDNFGLITFTVGPRYVFNDLDDAGPGLAALDALRYFTVLRLLLDDRKALAELMELYEDMLQGNEPLRELPEALYPDVAARDARQLAKWTEGEAFRFDEPSLNLSRAEAGTGDRLLEALGRSGQLSEVEVLALAHRDRDAGGSGGLERYLILGRERGGERRLRLLELKETTHAATSWNNFLHEDEDRLERAKASIWRGLEVPFYREVQVGRSVYLLRDRLGRASVDIEALSKRDLRAVLEAQVSILARQHAEAFAGLDLDKLDDWLRESLDVTARRWLKAYERARRR
>NC_021658.1|WP_044985771.1|3494963_3496472_-|hypothetical-protein
MKLSKFALFGMIALAGCSAGGGGTEAEEDTGQIELNLIGAAASGTVYRLRDGIVMVQGPQDTIFFDTEDDPNRARLSADVPTGSYYTFLQEGWRLERLNLDNTIEPVEAQFLSPNPQWFNVYADQNTLVPLRFRVGGDDVVLDRGSFDIVIEVEEAPSTSTLCTDDSECGPGGTCCLAGFVGTCTQLGEGEACPLPDLTVSADVAQFSLSIDHESFPADSCAIVEGCVGGAGDRRLMRFSTETPNVGEADMILGNPTDVDGFEYSACHGHYHFEGYARYELLDGTGAVVATGHKQAFCLLDSSPVGIPGSPSTSRFHCGFQGIQRGWSDVYTSGLDCQWVDITGVSPGDYFLRITINADRTLPESDYGNNTIEVPVTIPEDGPTEPGDPLSACSDPVGGEWRDCGWSIAPGYEAVACDPNTVITVGCGCPSGTCGDDPIMRVCDGPAACTGAEALSSVDDACGYCPQTQFVCPESGVYTVLVASYDATAAFTCDVSATVATP
>NC_021658.1|WP_148314779.1|3496832_3497300_+|MerR-family-transcriptional-regulator
MTYKLDELAGEAGVAPRTVRYYVQRGLLPAPEFRGKDTSYGREHLVRLRAIKVLQQAHLPLEEIQARLAGAGLDEIERIAAGAPPAAKAGTCAGPAEAAAASTPAAGAPRGARWERVEIADGVELHVRGDAPERSRRIALDIESRYATLAPKGSR
>NC_021658.1|WP_020734495.1|3497296_3499900_+|VWA-domain-containing-protein
MTPSIDPSLPAATPSSCLRSSEGHPVPLLGVSLSGEVFGGAARLVVRQRYRNEERRPIEAIYTFPLPSEASIAGFAMECAGRRLEGEVKEREEAFQAYDEAVATGHGAALLDEERRNVFTASVGNLLPGEETVVEVAFVQRLQADEGALRLMIPTLVAPRYIPGKAGGERTAHGAHEPTDQVPDADRISPEIARVDYGIAVDIVFDLGRDVAIESPSHALAVRREEGSRQRVSLRGDKAALDRDIVLIAAGAPGVSAGLVCDRAAGKEGTFALTIVPDLFDAQRSSARRDVVFVVDVSGSMQGESIDQAKRALRLCLRHLAEGDRFGVIAFSNTFRALEPSLAPFTQRTLEAADAFVEGLVASGGTEMLQPLLAAAGMLGDKERDRVVVLLTDGQVGNEAEIVDRVAEQGQGVRVYTFGIGTNVSDLLVNDLARRTQGAAEFIHPGERIDEKVTAQFARATAMRVTGLEARFEGVDVGELSPAELPALVDGEPWVLYGRYERPGVGRVELRGSLRGERFHLAVPVELEAEASRPGLEALWAGARVRELEASERGLSGKRAEAMRKRIVDLAVRHRVASKHASFVVIERRTGDRRAHGQPEARPVPVSAPAGWGMSRRGPAAPAAAFAAMGGPMIGGPSMRANSFMKARASGPAPMAMSAPAPRAAESSPAPAARGLLSRAKQLFQPSAAAGPASVAAPAGAVARCGPAGQQHGSGPGGPPAPAPGAAPGGAEPEGAGLGRMFEEQLASGLWERGEPTDLGRLTRTARCLAACHEQGVDSAHPIYGAQVAKAIEALCALAGSLLQRGGADGEVAAALAAAYLVASGRRLRARVHDAVAAAAPEAVRAVLGELGDAGALRRRVEALRGA
>NC_021658.1|WP_044985772.1|3499945_3500992_-|hypothetical-protein
MIRRKGACQVQLPALGVAAVSAEGSAGIAPSLPVRAGGVGRRLVALLAPALLVGCGYTEFEMKAQLDRSERLQRELQTSQQRVRQLEQDVARGGVAAPPREDPLSAEGIDLGAGPGAGAQRGEAAGARPAAERDSGVLRAFLPVAAGDVTVAPRDGRVVISIPTRVLFKGNRDALSPAGEKILRDVAAIIRGNEPLKGLDYQVVGHTAGGAPGVAPGVAWRNGWDVTVAQARAVLLFLAQPKEAGLPVARLSLASFADLPPADVGGGAPAQPADPRLEIVVEGTAQIAERPAGEARPVGATPAGATPAGGTAPAGAAPAGAARPGGAARPAGEARPGTGTKGGDDTYP
>NC_021658.1|WP_020734497.1|3501273_3502680_-|phosphatase-PAP2-family-protein
MHRSPASWAPIAFAVTAACLLGGRASAHEPECPGDPPDRDAVLDWNAVALDAVARDYSDPSRRPPEQEGPTRASRALAIVHAAIYDAVNSIVPRYEPYIVYTRAPDASVDAAVATAAYRTLTALYPRQTAALDAALYAYLAEIPASDAKEDGIVLGNEVAEDILAARARDGADAPMPYTPRYAPGDHRVDPLHPDQGFLTPRWGEVTPFAIESGDQFRAPPPPSLRSLSYALSFYELFALGGDGESTPTLRTPEQTVIGIFWSYDEAPRIGVVPRLFDQIARVVAVQEHNSEIENARYFALVNFALADAAIATWDTKYHYNRWRPIIGIRLANIDGNPLTVQDEHWTPLASPGSNGGPLHETPAFPSYVSGHASLGAAMFQVLARYYGTHHVPFCVVSDEYNGRTTDARGDVRPRLRRCYSGFREATQEVAISRIYLGVHWRFDAMNGMRLGRNVGDAVFDGSLQPLD
>NC_021658.1|WP_148314780.1|3503293_3504388_-|FAD-dependent-monooxygenase
MADIAVVGGGPAGLAVAIGCAQRGHDVLVLDQAAWPIDKACGEGVMPEGCRALEELGVLSELDPAERAPIEGIRYLRPDGLRVEAPLPAPGGLGVRRTALSAALSARARAAGARLAAGEPLVAVERTRAGARLVTRRRAVEARYVVGADGLGSRVRRALGWDAPPAGPRRLGLRQHFRCAPWSSFVEVHLGDGVEAYVTPAGPQRVGVAFLWDGDRLEGRASTERLVRRFPALAERVAGAPVDSTARGSGPLERASSRLHDDRFVLVGDAAGYIDAITGEGISLALVGAAALSTALDAALRGGGAAPLAAYARVFRQAFLRYAVATRAVLFIARRPRLRDGLLSALALAPGLFRHAVGAVLRPR
>NC_021658.1|WP_020734499.1|3504402_3504996_-|isoprenylcysteine-carboxyl-methyltransferase-family-protein
MVTSAQLYLAFLGAVAIERLAELVISRRNARRAFAKGGVEVGQAHFRAMALMHTAFLAACALEVDALDRPFPGLVGFAALAAALLAQAMRYWVIATLGEQWNVRIIVVPGAAPVSGGPYRYLRHPNYAAVIVEMVAIPMIHGAWLTALVFSALNAAVLSVRIRAEEAALGPSYAAEMGGLPRLVPGRRAAPERPSAP
>NC_021658.1|WP_020734500.1|3504989_3506066_-|type-III-polyketide-synthase
MPFAPTIAAVGTALPPHYATQDETCAGLRRLWAGKGDALALVERVRRSIEVRGRHLALPIDAYYAPSTFAAQNGRWSACAMELGERACRAALDRAGLRPEDVDHIMFVSVTGISAPSLDARLVNRLGFRRDVKRTPVFGLGCVAGVAGVGRITDTLRAFPGQTSLLLSVELCSLTLQRDDTSAANVIAAQLFADGAAAVVARGAQAARKSGRTGGAAVLDAQAVFYPETEHIMGWDVVDTGFRVVLSAGVPALVREHVRRDVDAFLARHRLSRGDVRHWIVHTGGPKVLEAITETLELPEDALARSWRSLREIGNVSSASVLFVLRDVLEEADARPGDYGVMMAFGPGFCSEIALLRW
>NC_021658.1|WP_020734501.1|3506272_3506644_+|EamA-family-transporter
MAQGYLFLIIALVFNATANILMKLASRRVPPMEGLSLVDKALALATNYHLVLGLVLFASNILFYVLALKRINLSVAYPIMSSGGFLIISVFSVYYLRETLTAVQIGGIVLIAAGIAMVAYNLS

Crispr_ID: NC_021658_9

• CRISPR_ID: NC_021658_9
• CRISPR_location: 3678210-3678313
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_9

Consensus_repeat	Method
GCGAGCTGCTCCAGGACGATCCGCTCCACGGC	CRISPRCasFinder

spacers of NC_021658_9

>9.1|3678242|40|NC_021658|CRISPRCasFinder
CCCGCTCGCCTCGGGCCCCTGGCGCTGCGGCCGGAGCAGG

CRISPR arrays and Neighbor proteins around NC_021658_9

CRISPR arrays

The CRISPR arrays of NC_021658_9

>merge|NC_021658|9|3678210-3678313|CRISPRCasFinder
GCGAGCTGCTCCAGGACGATCCGCTCCACGGCCCCGCTCGCCTCGGGCCCCTGGCGCTGCGGCCGGAGCAGGGCGAGCTGCTCCAGGACGATCCGCTCCACGGC

>NC_021658|9|7|3678210-3678313|CRISPRCasFinder
GCGAGCTGCTCCAGGACGATCCGCTCCACGGC	CCCGCTCGCCTCGGGCCCCTGGCGCTGCGGCCGGAGCAGG
GCGAGCTGCTCCAGGACGATCCGCTCCACGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_044985793.1|3707974_3709237_-|DUF4215-domain-containing-protein	unknown	unknown	gnl|CDD|200169
NC_021658.1|WP_044988124.1|3711777_3712545_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_021658.1|WP_044985790.1|3639727_3640801_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NC_021658.1|WP_020734623.1|3706874_3707747_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|272862
NC_021658.1|WP_020734615.1|3640941_3641997_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274922
NC_021658.1|WP_020734608.1|3635193_3635397_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044988117.1|3638844_3639768_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_021658.1|WP_148313530.1|3688176_3702843_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|225858
NC_021658.1|WP_187345921.1|3633442_3634417_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|225176
NC_021658.1|WP_148313531.1|3705138_3706239_+|3,4-dihydroxy-2-butanone-4-phosphate-synthase	unknown	unknown	gnl|CDD|237587
NC_021658.1|WP_020734625.1|3709466_3710753_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270303
NC_021658.1|WP_187346046.1|3642043_3643021_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|225856
NC_021658.1|WP_020734611.1|3636717_3637377_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_021658.1|WP_020734612.1|3637910_3638495_+|protogloblin-ApPgb	unknown	unknown	gnl|CDD|381264
NC_021658.1|WP_044985792.1|3706352_3706865_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224427
NC_021658.1|WP_080682719.1|3710851_3711661_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_021658.1|WP_049949495.1|3653022_3666846_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|237108
NC_021658.1|WP_020734610.1|3636213_3636468_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044988123.1|3703818_3704625_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|225136
NC_021658.1|WP_020734628.1|3712541_3714896_+|alpha-xylosidase	unknown	unknown	gnl|CDD|236731

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_044985793.1|3707974_3709237_-|DUF4215-domain-containing-protein	gnl|CDD|200169	TIGR02232, myxo_disulf_rpt, Myxococcus cysteine-rich repeat. This model represents a sequence region shared between several proteins of Myxococcus xanthus DK 1622 and some eukaryotic proteins that include human pappalysin-1 (SP|Q13219). The region of about 40 amino acids contains several conserved Cys residues presumed to form disulfide bonds. The region appears in up to 13 repeats in Myxococcus.	7.10386e-07
NC_021658.1|WP_044988124.1|3711777_3712545_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.23018e-62
NC_021658.1|WP_044985790.1|3639727_3640801_+|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	1.66457e-26
NC_021658.1|WP_020734623.1|3706874_3707747_+|SAM-dependent-methyltransferase	gnl|CDD|272862	TIGR00027, Hypothetical_protein_Rv0893c/MT0917/Mb0917c., methyltransferase, TIGR00027 family. This model represents a set of probable methyltransferases, about 300 amino acids long, with essentially full length homology. Members share an N-terminal region described by Pfam model pfam02409. Included are a paralogous family of 12 proteins in Mycobacterium tuberculosis, plus close homologs in related species, a family of 8 in the archaeon Methanosarcina acetivorans, and small numbers of members in other species, including plants. [Unknown function, Enzymes of unknown specificity].	6.68327e-68
NC_021658.1|WP_020734615.1|3640941_3641997_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274922	TIGR04020, non-ribosomal_peptide_synthetase, natural product biosynthesis luciferase-like monooxygenase domain. This model describes a subfamily within the bacterial luciferase-like monooxygenase (LLM) family that regularly occurs within large non-ribosomal protein synthases/polyketide synthases, but also as small proteins. The LLM family includes members that bind either FMN or F420, and FMN is more likely in this case because many members are from species that lack F420 biosynthesis capability. An example member is the MupA protein of mupirocin biosynthesis in Pseudomonas fluorescens NCIMB 10586.	0
NC_021658.1|WP_148313530.1|3688176_3702843_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NC_021658.1|WP_044988117.1|3638844_3639768_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	9.21538e-93
NC_021658.1|WP_044988123.1|3703818_3704625_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	1.772e-25
NC_021658.1|WP_187345921.1|3633442_3634417_-|alpha/beta-fold-hydrolase	gnl|CDD|225176	COG2267, PldB, Lysophospholipase [Lipid metabolism].	1.26041e-10
NC_021658.1|WP_020734611.1|3636717_3637377_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.07729e-15
NC_021658.1|WP_020734625.1|3709466_3710753_+|extracellular-solute-binding-protein	gnl|CDD|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.07678e-44
NC_021658.1|WP_187346046.1|3642043_3643021_-|alpha/beta-fold-hydrolase	gnl|CDD|225856	COG3319, COG3319, Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism].	4.25958e-40
NC_021658.1|WP_148313531.1|3705138_3706239_+|3,4-dihydroxy-2-butanone-4-phosphate-synthase	gnl|CDD|237587	PRK14019, PRK14019, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II.	5.02822e-107
NC_021658.1|WP_020734612.1|3637910_3638495_+|protogloblin-ApPgb	gnl|CDD|381264	cd12124, Pgbs, Protoglobins (Pgbs). Pgbs are single-domain globins of yet unknown biological function. Included in this subfamily are Pgbs from the strictly anaerobic methanogen Methanosarcina acetivorans (MaPgb) and from the obligate aerobic hyperthermophile Aeropyrum pernix (ApPgb). MaPgb is a dimeric globin which in addition to the 3-on-3 helical sandwich contains an N-terminal extension. This extension, along with other Pgb-specific loops buries the heme within the protein; two orthogonal apolar tunnels grant access of small ligand molecules to the heme. Like other globins, MaPgb can bind O2, CO and NO reversibly in vitro, however it has as unusually low O2 dissociation rate, along with a large structural distortion of the heme moiety. CO binding to and dissociation from the heme occurs through biphasic kinetics. ApPgb also contains heme, and can bind O2, CO and NO. This subfamily belongs to a family which includes the globin-coupled-sensors (GCSs) and single-domain sensor globins. It has been demonstrated that Pgbs and other single-domain globins can function as sensors, when coupled to an appropriate regulator domain.	2.20093e-116
NC_021658.1|WP_044985792.1|3706352_3706865_+|MarR-family-transcriptional-regulator	gnl|CDD|224427	COG1510, COG1510, Predicted transcriptional regulators [Transcription].	8.52096e-08
NC_021658.1|WP_080682719.1|3710851_3711661_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.34881e-75
NC_021658.1|WP_049949495.1|3653022_3666846_-|non-ribosomal-peptide-synthetase	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NC_021658.1|WP_020734628.1|3712541_3714896_+|alpha-xylosidase	gnl|CDD|236731	PRK10658, PRK10658, putative alpha-glucosidase; Provisional.	0

Protein sequences

>NC_021658.1|WP_049949495.1|3653022_3666846_-|non-ribosomal-peptide-synthetase
MNLVRYLESLGVEFSLEGEQLRIRAPQRLLSPELRRELSSLKEAICDFLVQRRVSGGRSAPLAPIDKAPRHGEAPLSFAQQRLWFLEQLHPGSPLYNLPMAVRLDGPLDVQALERSVREVVRRHEALRTTFVVEGGQARQVIAPQPCFSLPVLDLGALPACEQEAEVRRQAEAEAQRPFSLAEGPLLRARLLRLTERAHALLLSMHHIVSDGWSLGVLVRELAALYEASSTGRPSPLPELPIQYADYALWQRRWLSGEVLQAQLAYWKHQLTGAPALLDLPTDRPRPADRTYRGAAQPVALSAELCAALRALSRRHGATLFMTLLSAFQLLLSRYARQDDIVVGTPVAGRTQVQTEGLIGFFVNTLVLRTDLSGDPTFVELLGRVRDVALEAHAHQDVPFEKLVEELAPARDLRRSPLFQVMFVLQNAPLPELRLGEATLEAMALKSSMAKFDWTLALEETSQGIEGALEYNTDLFEAASIARMLGHFRALLEAIATDPEQRISALPLLSAAERHEVLVAWNGTSVGFPQEACLHELFEAQVERTPDAVAVVLGEQGLTYRALDRRANQLANHLRALGVGPESRVGLHAERSLDMVVGILGILKAGGAYVPLDPIYPEDRLGFMMADAALSVVLTQERLISSLADSSARVLVLDSGWDQSGAPSDERPRSGAAPENLAYAMYTSGSTGRPKGVLVTHANVVRLLRATQRWFNFSERDVWTMFHSFAFDVSVWEMWGALLHGGRLVVLLSLEETAGGMTGTAEYATDLFDAATVARMMANLRTLLESIVEAPERRTTELSLLTREERHQLLWGWNDTEVDRPHERCVHELFEAQVEATPDAVAALFEQQELSYRELNRRANQLAHHLRSLGVGPDVLVGLCVERSLSMPVGLLAILKAGGAYVPIDPSYPEERIAVMCEDSAARVLLTQASLAPRLPRGGARLLCLDSDGDSFARAPCHNPAPSTTPDDLAYVIYTSGSTGEPKGVAMPHRPLINLLSWQLRNRVRPGGARTLQFASMSFDVSFQEIFSTWSSGGALVLLREDERADPSILLRRLDELGVERAYLPPVVLQQLADAAAREGRVPSALREIIAAGEQLVVTRAIADLLRGLSGCSLQNHYGPTEAHVVTAFLLPEAPELGPAPIGRPIDNVRIHLLDARLEPVPIGVAGELFIGGTCLARGYWRRPELTGQRFIADPHGGEPGARLYRTGDLARYRPDGCIEFLGRTDRQVKLRGFRIELGEIEAVLNRHPDVREVAVVLREDAPGDRRLVAYLVARNAAPPALAELRSYLQSRLPAYMVPAAFVWLPVMPLTPNGKLHREALPAPSPRGPEQDGGFVLPRTPTEELLAGLFAEVLHLDRVGALDDFFELGGHSLLAAQLSSRIRASFAVELPLRALFEAPSVAGLSVQLEAARRRGTPLPPAIEHAGREAALPLSFAQQRLWFLEQLHPGSPLYNLPMAVRLDGPLDVHALERSVREVVRRHEALRTTFVVEGGQARQVIAPQPCFSLPVLDLGALPACEQEAEVRRQAEAEAQRPFSLAEGPLLRARLLRLTERAHALLLSMHHIVSDGWSLGVLVRELAALYEASSAGRPSPLPELPIQYADYALWQRRWLSGEVLQAQLAYWKHQLTGAPALLDLPTDRPRPADRTYRGAAQPVALSAELCAALRALSRRHGATLFMTLLSAFQLLLSRYARQDDIVVGTPVAGRTQVQTEGLIGFFVNTLVLRTDLSGDPTFVELLGRVRDVALEAHAHQDVPFEKLVEELAPARDLRRSPLFQVMFVLQNAPLPELRLGEATLEAMALKSSMAKFDWTLALEETSQGIEGALEYNTDLFEAASIARMLGHFRALLEAIATDPEQRISALPLLSAAERHEVLVAWNGTSVGFPQEACLHELFEAQVERTPDAVAVVLGEQGLTYRALDRRANQLANHLRALGVGPESRVGLHAERSLDMVVGILGILKAGGAYVPLDPIYPEDRLGFMMADAALSVVLTQERLISSLADSSARVLVLDSGWDQSGAPSDERPRSGAAPENLAYAMYTSGSTGRPKGVLVTHANVVRLLRATQRWFNFSERDVWTMFHSFAFDVSVWEMWGALLHGGRLVVVSFEDSRAPDALHRLLRRERVTVLCQTPSAFRQLVEFDASSPASQQLGLRAVILAGEAIDLQSLRPWFKRHGDERPQLVNMYGITETTVHATYRPLRQADVDGASSSPIGRPLPDMQVYVLDPRQQLLPVGVPGELYVGGAGVARGYLNRPELSAERFIANRFVEQPGARLYRTGDVGRWLPDGTLEYLGRLDHQIKLRGYRIEPGEIEAALEQHPDVQQAVVLAWQDAPGDKRLVAYVVTRQGAAPPEGELRGWVRNRVPEYMVPSAFVRLAAIPLSPNGKIDRDALPAPSCARPEQQGVFIAPRTPTEELLAGLFAEVLHLDRVGALDDFFELGGHSLLAAQLSSRIRASFAVELPLRALFEAPSVAGLSVQLEAARRRGTPLPPAIEHAGREAALPLSFAQQRLWFLEQLHPGSPLYNLPMAVRLDGPLDVHALERSVREVVRRHEALRTTFVVEGGQARQVIAPQPCFSLPVLDLGALPACEQEAEVRRQAEAEAQRPFSLAEGPLLRARLLRLTERAHALLLSMHHIVSDGWSLGVLVRELAALYEASSAGRPSPLPELPIQYADYALWQRRWLSGEVLQAQLAYWKHQLTGAPALLDLPTDRPRPADRTYRGAAQPVALSAELCAALRALSRRHGATLFMTLLSAFQLLLSRYARQDDIVVGTPVAGRTQVQTEGLIGFFVNTLVLRTDLSGDPTFVELLGRVRDVALEAHAHQDVPFEKLVEELAPARDLRRSPLFQVMFVLQNAPLPELALGQMTLSPLPVESATAKFDLTLSLQETEAGVQGHLEYATDLFDAATVARMSGHLRTLLEGIVADPHRRLGALPLLTPEERHELLCVWNRTDVEYPKGRCIHELFEAQVEAAPEAVAVVFEGQQVSYQELNRRADRLAHHLRSLGVGPGVLVGLCIERSIEMVLGMLGILKAGGAYVPLDPAYPKARLAFMMVDAAAPVLITRQALLSRLPAQAPSVLLLDALEADRVDGAADHNSNPVATTGPEHPAYVIYTSGSTGQPKGVVVTHASLCNLASWHRRRFEVTAEDRIAQLASFSFDSSVSEVWPCLAAGAHLHIVPDEVRSEPERLARWLCDEEIDIAFAPTPLGEMLLEQPWPSRTKLRALRVGGAPLKRRPSPESPFEVINEYGPTEGTVVATTHRVASDEAGVIPIGRPIANVRVYVLNDALQPQPIGVPGELYLGGLGLSRGYLSRPELSAERFIERPFEEEPGARLYRTGDWCRFKADGVLEYVGRMDQQVKVRGFRIELGEIEAVLGQHPAVQQAVVMAREDTPGDRRLVAYVVAREGTSQLASELRDHLGERLPEHMVPSAFVPLAALPLSPNGKIDERALPAPGGARPEQKNAFVAPSTPAEQVLAGAFGQVLGLSRVSVHDNFFSLGGDSILAIQVVSKARQAGLYVSVRQLFQHQTIAELSAVATLAPSSLAEQGAVAGPVVLTPIQRWFFEQAWPEPHHFNQTILLEVRQALNPVLLERALQHLVSHHDALRMRFVREGEGICQAHAGLAGSVELTTVDLSTVPAEQQARAVEATSAGVQTRLRLDEGPLLSGALMDLGPGRPGRLAIAIHHLVVDGVSWRILLEDLETAYVQLAHGEPARVPLKTTSFQRWAERIAAHALSGPVREELPFWLATPAARRLPVDIEGGEDTVASAATVVVALEADETRALLQDVPEVYRTQINDVLLTALGQAFAPWTREHVLRFDLEGHGREELFPDLVLSRTVGWFTALFPVALSLPPASPAEALKAVKEQLRRIPQHGIGYGLLRYLHPDPAIAAELAAQAPSEVSFNYLGQLDAGVSASSLFGWAEEPSGPAQSPRARRTYRLEIKAWVAGGRLEVGWTYSENLYRRPTIERLAERFLAALRALLSHCLSPEAGGRTPSDYPLARLSQAAVDALAGRGRDVEDIYPLSPLQQGLLYHTLRDPASGVYVEQLTFRIASGLDVEALRASWQQVLERHPILRTSFAWEGLDEPVQVVRTGVTLPWAEHDLRGMSSGDLEAWLENFLAEDRDRGFDLARAPLMRCALLRRTDEAYQLVLSHHHLLLDGWSMPLLFGELFAYYEAACRREAIRLPSPRPYRDYIAWLGQQDLGRAEAFWRKALAGFDEPTPLPAGRRNGAAAPALSQAVERRLSAAVTEALDQVARAGALTLSTLVEGAWAILLSRYCDRDDVVFGATVSGRSAGPERVDAMVGLFINTLPRRVRLSQDAPLGAWLKQLQEQQAEQLSYDYSPLASVQGWSEIPRGQALFQTLLVVENYPVDAAIEQAEHWLPVEDVRVLEQTNYPLTVVVAPGPELVLRLLYAADLFDAGTIARMAGHLQTLLEGLAEGPERRIGELGLLTAAERRQLVSEWNGTGVSYAEEACLHELFEAQVERTPEAVAVVFEGQTLSYRELNRRANRLAHRLRSLGVGPEVLVGLCVERSVEMVVGIVSILKAGGAYVPLDPSHPAERLGIMLEDAGEPTGSRTGSGRWASGPRCWWGCAWSGRWRWWWGS
>NC_021658.1|WP_187346046.1|3642043_3643021_-|alpha/beta-fold-hydrolase
MARIHERFGQAFPLSTLFQGSTVEALAQRLRERARPRPWAPLITIQPAGVGRPFFCVHPGGGNVLCYADLARHLGEDRPFYGFQARGIEDDQQPHHRIEDMAAQYVEALRAVQPEGPYLLGGWSLGGHVAFEMAHQLLRDGQRVDLLAILDSSASGPAASPPEPAEDDVRILVELARGFEVSISDDYLRGLGPDDQVGYLVDCIVRQSLLPPGFSVLEARRIARLVRASVQALERYAPRLYPERITLFRASEQPAPPALEGAQPALLDPTAGWRELSPHPVEVHEVPGTHHTMVREPHVRILASRLRRCLLAVDPLPSGVTQAAA
>NC_021658.1|WP_020734615.1|3640941_3641997_+|LLM-class-flavin-dependent-oxidoreductase
MDFSLLFFSSNEADFADDKYRLFFETSKLADARGFKAIWAPERHFHAFGGLYPCPSLLCGALAMVTRRIRLRAGSVVLPLDHPVRVAEQWSVVDNLSGGRVDVAFATGWNPNDFVLAPESYEDRVALLFSRILTVKALWCGEGVSFPNGKGEMASVRLYPQPKQPDLPVWITCSGGEERFVQAGAFGANVLTALILQSLDDLATKIAAYRRARAEHDHDPAAGKVTLMMHTFIGDRVEEVRQAVQRPFMSYLRSAVELWGAFWKELQALPPAEQEEVIVLAFERYFRTAALFGTPETCARTVERLAAIGVDEIACLIDFGVDLDATMASLHRLSAFKDRFAGAAWAARGTP
>NC_021658.1|WP_044985790.1|3639727_3640801_+|ABC-transporter-permease
MSSSTSPAGSFVSSVQRPALRELVLTRLRSFYREPSQVFWTFFLPILVATVLWIAFRSGPPQPAAVAVAEGPEAEPLRAVLDASSEVTAEALDAGAARAALRAGKVDLVVVPGARPVYEFDPTRPESRLARMLADDVLQRAAGRGDPVEAVEVKTTEPGSRYVDFLVPGIIGVAVMSSGLWGVGFAVVELRTKRLMRRFLATPMRRSDFLLSFLLSRACFLGLEISTLLAFGALVLDVPIRGSLALLMAVAASGALMFAGLGLLLASRAQNMQTAGGIINLVSVPMYLASGTFFSSSRFPDALQPLVRALPLTPLNDALRAVMLEGAGASEVLPQIATLLTWGAVSLAASVKLFRWE
>NC_021658.1|WP_044988117.1|3638844_3639768_+|ABC-transporter-ATP-binding-protein
MSFAIRCRGLTKRYGDVHALRGLDLDVHTGECFGLLGPNGAGKTTMIEILEGLREPTAGDAEVLHRRWTTHERALRERIGITLQQTSLPERLTAREILSLFRSFYAKGREVNELIRAVQLEDKQDAQYEQLSGGQKQRIAVACALVGNPELLFLDEPTTGLDPHSRRNLWDLVLEFRAHGGTVMLTTHYMDEAERLCDRVGVIDGGVLMALGTPRELIAALGGEVMIGFAVEPSEGVDVAALGALPSARMSRRDADGFSLAVEAPHIALPALLDLLARVGARLTRLSMQRATLDDVFVHLTGRQLRE
>NC_021658.1|WP_020734612.1|3637910_3638495_+|protogloblin-ApPgb
MTIHGYTLGTGAVAKSPVSPADFEDMKKSALFGEEDVKYLRLSHDIVKDQVEPILDVWYGFVGANPHLLASFTGKADGKPLGDYLGGVRKRFGQWILDTARAEYDQKWLDYQHEIGLRHHRIKKNKTDGAPSTDLVPFRNLFALIFPVTFTLKPFLATKGHPAEDVERMHAAWVKSCLLQLTLWSYPYVKEGDF
>NC_021658.1|WP_020734611.1|3636717_3637377_+|MarR-family-transcriptional-regulator
MGRSLPLFFEENSEPIDRRIAVGLRKLGLAMKLQAWEQASHEGLSPTQGQILATLSLEGPLSGSELSQRLGVTLATISESVRALVDKGAVVKRPDPRHPRASLIELTPQGRALAEKVTTLPDAIVSAVSALSASEQEAFLAGVVKIIRSLQIGGHIPVSRMCVTCKYFRPNAHQGALPHHCAFVDAPMAGRHLRIDCGEHELAEEQQREDPWRRFVQPE
>NC_021658.1|WP_020734610.1|3636213_3636468_-|hypothetical-protein
MNENLHAAPLDETPRARTNILRALPIALALLCGACSKELGDGPWAGAAGGPTHPTGSTRAGAALQFASAEPGVVQRVQQPSRSR
>NC_021658.1|WP_020734608.1|3635193_3635397_+|hypothetical-protein
MLAPASLKYLLRTRQAERTRKKSQSFRRKPPPVQKNGAGDWHPQKITATAQTRHPKAQARAANTPTR
>NC_021658.1|WP_187345921.1|3633442_3634417_-|alpha/beta-fold-hydrolase
MAHLASVLLPVCTSFRYAVALAPGAPADYEVAAELCVPQDSPRDTVLLTVHGTTYSSVYWDFPYQPERYSFVRYANAAGYATLNFDRIGTGDSDRPPSLQVTPTAQAYVHHQLAEALRSGELGRAWSRVVLVGHSLGSIISVQQAATYHDVDGVVVTGFLHTYGPGLPQLLLNVHPAAIDPSFAGAGLDLGYLTTRPGTRGSLFYYRPNADPAVIALDEATKGLGTSGELAEFALVNTALTSLQVDAPVLTVVGRHDTVFCGIAPCGTLLSGTTLEPAAYAPAAELEIVVVPNAGHDLNLQINAPTAYAAIRGWLDERFPPLGN
>NC_021658.1|WP_148313530.1|3688176_3702843_-|SDR-family-NAD(P)-dependent-oxidoreductase
MSQATDEAARRAAVRTEEEIRTWLIDRLVALGRIPLRLVDTCERFSRYGLDSLSAMHLFADLSQALGRDLPPTLIWEHPTIDALSRHLAGLAGAAAARGADALASPEDVSAAQPSAREPIAVIGMACRLPRAPDIEEFWRLLREGVDAITEAPRARWNADALFDRELAAPGKMNTRWGGFLDHVDQFDPLFFGISPREAVHMDPQQRLMLELAWEALEDAGVVAGELKGSRTGVFFGVVWTDYAALAQQAGAAAVAQHTVTGLHHSIVANRVSYVLGLQGPSLALDTACSSSLVAVHLACESLRRGESTLALAGGVNLNIVPESTMQVSKFGGLSPDGRCFTFDARANGYVRGEGGGVVLLKPLSRALADGDPIVCVIRGSAVNNDGASSGLTAPNPSAQVDVLRSALRQAGVDPAAVDYVEAHGTGTLLGDPIEAAALGSVFGAARPAERPLLVGSVKTNIGHLEAASGIAGLIKVALCIKHRELPPSLHFKTPNPYIPFNELHLSVQRTISAWPDTDRLATAGVSAFGFGGTNCHVVLQEWPAPQAELLPLSAERPDALRTAAQKLLGHLPPAEARSSVQELCRALALRSSDGDHRLAITARSCRELGQKLQRCVDGEPGPEPNGVAGGPGIASGIAEQGRLGKPVFVFSGQGSQWLGMGRSLLAREPLFRAVLRDCDRLIRRCVGWSLLDELTAGSERARMDEIDVSCPAIVSIQVALAALWRSWGVEPALVVGHSIGEVAAAHVAGALSLEDAMLVICTQGRLIRRIRGQGAMGLVALPWDEAGEALAGREGRLCRAIHASPDATVLSGEPEALAEVFATLGQRGVFCRQVNVDVAAHSPQVDPLREDLLEALQRVSARPARVPICSGVTGSTLEGERFDASYWARNLAEPVRFADAMASLIQRGHSVFVELSPHPLLKHAVTSCLDHVGQRGVVLASLRRDDDERAALLDAVGALYASGHPVRWSEICPAAGAGVDALDLMADNPAPASDAAAGSVPEPEPAESWYVLPLSAHSPEALSAHADAYRSLLSRAWPSGARSIRDIAYTAGARRSHHDHRLAAVACSPEGLVASLETFVRGGEMCAGLVHGQAGPRAQRKVVFIFSGQGSQWAGMGRELLAREPVFRAAVERIDALVARRAGFSILRELAAPEDRSRLHGTDVAQPAIFALQAGLSTLWASWGIAPDAVVGHSLGEVAAAHVAGALGLDEAVRLVCARGRVMQQAAGLGKMASVALGAEEAARALRGVEERVCIAAINDPGAVVLSGAAAALEEAVANLKLQGVRCCYLPGSHAFHSPQMAPLAGELREALGAMALDGPKLPLYSTVTGARLSDVELDAAYWARNLREPVRFASAIGAAIDDGYRVFLELGPHPVLSSNVEQCLAARAVEGRAVSTLRRGREERRSLLEALGALYVCGCAVDWERLYPSGGRVVSVPRYPWQRKRYWLDPGPAAHAAPRGAASGHPLLGARLPVATVGAAFEAALSVETAPYLADHRVFDEVVLPGAAVLEMARAAAVSRFGHERVSIEDLLLQAPLLLPETGGVRVQVVLSAEAGQDTTVTVCSQTLEAAPEHAWTVHAKGRVQPWSEEACWTAVDLAAVQARCQAVVPAADMYAACGDAGLAYGPAFQGITALWRGHREAIAQVTLPARELEDAGAYGVHPALLDAALQTLLAALDPWCASAPLAVLPVGVSGFRVWQPGATVAWAHARVHRAGEPDAPVMSGDVALLDALGRPIAEVSGIRLKHADRAALRSADSKAPQERLYRLSWMEAPQASGEQRPPERWLVLTDGSAVGEALVERLRSSGAICAVVARGPWQVTRDRGAAGASRMFPEALDAALADEPAGAPLRGVVVLWDETPSPALAGSPAERGDELAVAGLHLVRTLARRAAPAGARLWWVTRGAQAVEPGDVSDVAQAPLWGLGRVAMQEHPELRCTLVDLDPSARTDDMAAALMRELTSADGETQVALRAGRRRVARLVRADAAAGLACPEAVSYRLEHGRRGLLSELHLAAAERRAPGPGEVEIEVTASGLNFRDVLAALNVYRGEAGPLGNECAGVIAAVGQGVDRLSVGDRVMAIARGTFQRYVTADARLVAPQPAGMTPAQAATVPVAFLTAWHALHDLGQLQAGERVLIHAAAGGVGMAAVQIAAWLGAEVFATASPPKWPVIEAMGVRHRASSRSPEFAALFRAATQGAGMDVVLNSLAGEHVDAGLSLLSPGGRFLEMGKTDVRSSEVIARDYPGVRYCAFDLWEVGPERIQAMLELLLEGFASGKLRPLPVRTFAISDAEAAFQLMAQARHTGKVALLPAPGPRIMADCSALITGGLGALGLYTARWLAEEHRVRHLVLAGRRAPDREGAAAIEALRARGALVTVAQVDVADATAVRSLLASLPRHLPLRIVIHAAGVLDDGMLADQDASRLSAVLSPKVRGAWNLHSETRHMPLDFFVLFSSVASLLGPPGQGSYAAANAFMDALAHLRRAEGLPAQSVNWGPWSGGGMAGKLGEAHKARLARQGIGALPPPEAVALLGRAMSRGETQLGLLSLDARAARLSFAAASDVPPLWRALVAPSPARPRAADAGAYAVRLASLPREARPAAIEAAVRAEVAKVLSLGSPDDISAERPLQEMGLDSLMAVELRNALSARVGQPLPAALVFDCSTVAALARYLLEKALPEPTTGAAPPPPAVRAADNEPIAIVGLGCRFPGGVRDPESFWRLLDEGVDAIREVPKDRWDIDAYYDPDPDAVGKMYTRSGGFLSEVDQFDPGFFRISPREAARMDPQQRLLLETSWEALERAGLPQQCLMGSDTGVFVGLMYRDYGVLTSGAPEQLDGYVGIGCAGSVASGRISYLLGLRGPAMTVDTACSSSLVAVHLACQSLRARECSLALAGGATLVLLPDIFVEFSRLRALAPDGRCKPFDASADGVAWSEGCGIVVLKRLSDAERDGDPVLAVIRGSAVNQDGRSNGLTAPNGPAQEEVIRRALAQAAVAPSAVGYVEAHGTGTPLGDPIELLALGRALSAGRTPDRPVVVSSVKSNIGHTQAAAGVAGVIKAVLALQHQRIPRMVHFTTPSPRVAWQELPLQVAAEAVPWPATGAPRIAGVSSFGISGTNAHVVLEEAPRSAAASPTATRAVALLPISAKSPEALAAMARDYRACLAQATSEAPATLHDVAYTASVRRSHHEHRLALLGSSWEELVTSLDAFLSGEPRASVMQGQAAPGSRQPRVVFVLAGQGSQWAGMGRELLAEEPVFRAVLERCEPLVQRHGGFSLIDELAATEAASRLDETFVAQPALFALQVALAELWSAWGVTPDAVIGHSLGEVAAAHLAGILSLDDAVRLVVSRGRIMQRATGLGRMAAVALPEEEAAHALRGVEDQVSVAAVNDPGSVVLSGDGAALRRVVERLAQRKVHCRMLRVNYAFHSPQMAPFQQELLSAVGALEPRRPERPIYSTVTGARVDGELDLQHWADNIRAPVEFARAVEASIADGHDVFLEVGPHPVLSVHLRACLSSRAEQGLVLASLQRGQEERRSLLRSLGALYAAGRPVAWERLYPAGGRCVALPTYPWQQQRCWFEWGSPGGSAPVRPRSAGSRDEGHPLLGAPLPASEHPETRSWEQTLSAGALPYLSDHRLHGEAVLPGAAYVEMALSAAAGAGRAGTPALEHVRFERMLVIPPKGGRTVQVNLAMERHDHASFQILSREARGAPWQRHAAGRLRWSDGAAGAHPTKEAPHRIQQRCPRPMRGAEHYQRMRALGLDYGTCFQGVQELWVGSGEILGRVRLTDALAGQDGAYQLHPAFLDACLQVLAASLSAEARAPVDGRLIVPVGLRHARVYGRPGQEVWVHARPSAGPAADDGELTGDVDLLEDDGRVVAEVHGLRAQRLARGALPQAAPAGGEAPLFALEWHRKEPLARAPEVRPATGVLLLFTDRGGTGAAVASLLHERGEPCVQVVAGQRYARLAPGSYEIDPAHPGAFHALLRDALGKDLPCRGVVHLWSLDATAAADTTPESLEADLRLGSLSALLLSQALVQRGDRDAPRLFLVTRGAQAVGPDGGAASVSQAPLWGLGRTLALEHPELACTNVDLSPVSSPGEARSLLREIELGDREDQIALRADGRFAARLVRTSLASKAGTAVHPALEPARDRPFRLEIQEPGVLERLSLREIARRRPGQGEVEIEVEAAGVNFLDVLLALGVMPDDAAEASGASPGLGGECAGRVVALGEGVTDLEVGCEVFALAPWSFSSFVTTRRSFVARRPERLSCEQAATIPIAFLTAYYALAYVGRLREGERVLIHAGAGGVGMAAIAWAKHVGAEIFATAGNDEKRDLLRSLGVQHVMSSRSLEFVDEVRRITNGEGIDVVLNSLSGEFIDASFGLLRDHGRFVEIGKRDYYEDRKLGLRPFLRNLSFSLVDLRAMLTQRPELVSSLLEEVVRLFDAGVLGPVPCRSFPIAEAVQAFSTLAQAKHVGKIALTMRDPEARIAPALPADRPRIRADGSYLITGGLGGLGLSLAQWLAAQGARHLALVGRRGASAAARAVIAAIEGAGAQVEVIQADVSQYDDVSAVMRELGRRLPPLRGVVHAAAVLDDRRAADLSTESFRNVMKPKALGAWNLHALTRDIPLDFFVLYSSAASLLGAAGQANYAAANAFLDALSHHRCRTGLPAMSINWGPFSEVGLAAADDSRGERLASRGMRSLTPAEGLEALGRLLARPTAQIGVFELNVRQWLEFYPVAARSPLWAELLKEQDPGAPRSPGALSTRRALEDARPEERVTILEEHLSEQLCRVLCLPASKVDRTTGFSSLGADSLRSLELRNRIEASLGIKLPATLLFMCPNLTSLARHLIEEMGLSVETSDAAAPAGEGDAPCRFTEEVEKLSEDELLALFDDKPAG
>NC_021658.1|WP_044988123.1|3703818_3704625_-|class-I-SAM-dependent-methyltransferase
MTTTIRLTLDTPELAQAYETGSHRQFNHGKLLIAALGVRRGQRVLDVGAGTGRLAAYVAEIVGSEGSVVAIDPLPLRVDIARQKTRDNLATAVGRAEDLSAFATHSFDVVYLNSVLHWLDEGQKERALSEAARVLKPGGKIGFSTGSREKPHQLDPIQRKVLADLGKEAQGTIPHKLTVDEIRELLQRTGFIVDTVEIRTFVDHAADIDEILRQSGSGSFGNHLSHLSFDEKREVRDRLAKELEARRTPQGIRLERNLIFAIAHTADN
>NC_021658.1|WP_148313531.1|3705138_3706239_+|3,4-dihydroxy-2-butanone-4-phosphate-synthase
MRLQASVEQLRSGGMVILVDDEEREDEGDLVVLAEHATPAAINFMATHGRGLICLALTEAQVDRLGLPLMATRAGARRSTAFTVSIEAREGVTTGISARDRARTVAAAIARDASPRDLVSPGHVFPLRARRDGVLEREGHTEGAVDLARLAGANPAAVICEIINDDGTMARRRDLARFGARHGLPIVSIGDVIRHRVQREDVAARVGTTPFRPAGLSGEWRAHTYQLRRDRQLLLLTHGAPALSGDRAVVFTHRAALVSDLLGDADLFGALREIEAAGAGAVIYSPASADPGAEHTAGLDLAVAARELVELGYRRVTLLDSRAPRPAAARREIDLETGDPPAPADGHGALLLRRARAGDGAPILQT
>NC_021658.1|WP_044985792.1|3706352_3706865_+|MarR-family-transcriptional-regulator
MPKQGSRPVNPRPRLERSDLLGWVERVATYLAADGMPPIAGRILGWLMICDPAEQSAAEIADAIGASRASLTTNLRVLAAMGFVSRRTRSGSRTAYYRVDEDAWEKVVRRQVASLRSLGEIVDAGLDLVGRGSARAGRIRAAHEIFLWMTRAFEDAPPLPSGKRWSERIE
>NC_021658.1|WP_020734623.1|3706874_3707747_+|SAM-dependent-methyltransferase
MSNRAAKTAFGPMTIIVADQRYSPEQRLVQDDLAYRFLPAGLRFMMALARWRPLESALMQAAEKTALGIRGSMLCRKRYIDDKILEALRAGNEAVVVLGAGLDTRAYRMPALANVPVFEVDLPENIDYKRATLQRVLGGVPESVRLVSIDFETHDLAAGLAAQGYDIARRTFFVWEGVTQYLTERGVRETFRFLARAAAGSRLAFTYVRRDFLDGENFYGAEGAYERFKVKEKVWRFGMDPATVPAFLAEYGWTELEQMGPREFIERYVQPTGRALLVSEIERSVHAEKR
>NC_021658.1|WP_044985793.1|3707974_3709237_-|DUF4215-domain-containing-protein
MNVRLVAGLFVLALSAAAGCGDDDGQGGAGGNGGSGGAGGDGGADATSTGTGTGGSGGEPTGTGGSGGEPTGTGGAPTGTGGSGGAEPTGTGGSGGAEPTGETDCTNYEDDDGDGSYDCADTDCAATCAPIAEAACASATPIVSTTIHGDTSEGTSGLEGTCFLGNTGHGPEEIHLFTPPTGQSGTLVIELESPTDHSVYARSACADMFSEIDCSDESSPYEGLPDQERIEIYVRDGQAVPIVVDAYEPREAGPYTLNVRFTPIVCGDGTVDAIEECDDGNTTSGDGCSSTCVYELDVLCEDAAELAIGENTGSTTAGASVFEGSCIGWDLPEAIHRFTPPSDGTLTLTLSADADLGFYVREGCADFGSELECADDGGRGDDETLAIDVAGGEPLFVIVDTYMPIGGGPYTLTVAFTPAP
>NC_021658.1|WP_020734625.1|3709466_3710753_+|extracellular-solute-binding-protein
MIGRVKGAALLAVLAAGALTLAACGRSDDGASGGKELRVWHYEAPDSAMGVAWSEAIKEFEATHPGVKVKLEEKGFEQIQKTAPMILNSSSAPDVMEYNKGNATAGLLSKQGLLQDLTPEATKRGWDKVIGPGVQVVAKYDDKGIMGGDRWYGVPNYAEYTLVYYNKDLFKKHDVAVPTTFDELTKAMDAFVAKGVTPLANAGAEYMAQQYVYQLALDKADTPWVSAFQRYTGKTDFTDPAWTHGATTFADWVTKGYIAKSSVSTKAEDAGVGFMSGKFPMMFSGTWWFGRVAKEAKFDWDTFVWPGARMTLGSGGNLWVVPAGAKNKQLAYDFIDITLKKKIQNTLGNAGGVPVAADSAAITEPRAKKLIDGFNTLAQSSGLAYYPDWPVPGFYDQWVSQTQKLMNGDPPQSVLGGLQKSYDSGLPR
>NC_021658.1|WP_080682719.1|3710851_3711661_+|sugar-ABC-transporter-permease
MNLGTSFTEWTGVGTPTWVGLDNYRELATDGEFWASFRHNLLVIVGMAILPTMIGLVLASALTDLIDRHFGPRAASVLRACIYLPQVLPIVIAGIVWSWLLAPENGAVNDLLTAIGLGALAHDWLGDPATALWSVMGVMVWIQIGFPLVIFMSGLQRVDPSLYEAAEIDGASWAQRFWHVTIPQIKPEIFVVLLWTTIAALKAFPHIFVLTRGGPGGATNVPSYYSYVHFFEKTDVGYGSAIATVLTLIILALTIAFLRLQGRELGEEP
>NC_021658.1|WP_044988124.1|3711777_3712545_+|carbohydrate-ABC-transporter-permease
MLIPFAVVVFNALKTPAEYTANGPLAPPEGLHLEGIRTFWERVGFGRVLFNSLLISGSVAVLAVLLSVLNAYALGIGRIKLRMSVLVLLLMANTLPQESLVYPLYTLANELGLYDTRISVVIVFTVIQSAFGTYLLSSVMSAFPRPLLDAARIDGASRWQILWRVVVPVVWPTLTVMLVFFFIWTWNEFLIPLIFLISNDNQTVSVALGVLQGQRLMDATMSSAAALLGLLPTVVFFLIFQRTLSRGLTAGAIKE
>NC_021658.1|WP_020734628.1|3712541_3714896_+|alpha-xylosidase
MKFSDGYWMMRKGVHAAHPAEVLDIDAGPASLVVHAPVQRIRHRGDLLKGPVVTVSCASPMPDVIGVTLTHFAGERPRGPAFALAADPTGEVTVDDDAATLTSGALSVRVGRREGWRLDFLAGGRRLTGSAQKAMAILDTDDGRHYVREQLDLGVGHFVYGLGERFGPLVKNGQVVDIWNADGGTSSEQAYKNVPFFLTNAGYGVFVDHPGRVSFEVASEAMARTQFSVEGQSMRYFLIYGPTPREILRKYTALTGRPARVPAWSYGLWLSTSFTTDYDEATVSSFIDGMAERDLPLSVFHFDCFWMREFRWCDFEWDPRVFPDPRGMLRRLKSRGLRICVWINPYIGQRSPLFEEGRARGYLLRRPNGDVWQWDLWQPGLAVVDFTNPEARAWYAEKLDALLDMGVDCFKTDFGERIPTDVVYHDGSDPERAHNYYAYLYNQTVFELLRARRGEGEAVVFARSATAGGQQFPVHWGGDCESTFEAMGESLRGGLSLGMSGFGFWSHDIGGFEGTPDPALFKRWIAFGLLSSHSRLHGSRSYRVPWVFDEESVEVLRRFSRLKMRLMPYLAGAARQAYGEGLPMMRAMVVEFPDDPACTHLERQYMLGDDLLVAPVFSADGELSYYVPRGVWTHYLTGERVEGGRWVRERHGFDSVPLLVRPGAVIPEGAVEDRPDYDHARGVTLRVYEPADGARVTTVIPGADGDAVTTFTMSRRGPAVRVEAAGAPSAWSVLLVNRRVVGVEGGESAEHPMGALVRAAGGELVITLEEKGSATARGPQGDDR

Crispr_ID: NC_021658_10

• CRISPR_ID: NC_021658_10
• CRISPR_location: 3762660-3762973
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of NC_021658_10

Consensus_repeat	Method
CCGGAGGCAGCCAGCTGCCT	CRT

spacers of NC_021658_10

>10.1|3762680|22|NC_021658|CRT
GCCCGGGATCAGGATCGATGTC
>10.2|3762722|22|NC_021658|CRT
GCCTGGGATCGGAATCGGTGCT
>10.3|3762764|22|NC_021658|CRT
GCCCGGGATCGGGATCGATGTC
>10.4|3762806|22|NC_021658|CRT
GCCTGGGATCGGAATCGGTGCT
>10.5|3762848|22|NC_021658|CRT
GCCCGGGATCAGGATCGATGTC
>10.6|3762890|22|NC_021658|CRT
TCCCGGAACCGGAGCCGGCGCC
>10.7|3762932|22|NC_021658|CRT
CCCGAGGACCGTCATCAATGTC

CRISPR arrays and Neighbor proteins around NC_021658_10

CRISPR arrays

The CRISPR arrays of NC_021658_10

>merge|NC_021658|10|3762660-3762973|CRT
CCGGAGGCAGCCAGCTGCCTGCCCGGGATCAGGATCGATGTCCCGGAGGCAGCCAGCTGCCTGCCTGGGATCGGAATCGGTGCTCCGGTGGCAGCCAGCTGCCTGCCCGGGATCGGGATCGATGTCCCGGAGGCAGCCAGCTGCCTGCCTGGGATCGGAATCGGTGCTCCGGAGGCAGCCAGCTGCCTGCCCGGGATCAGGATCGATGTCCCGGAGGCAGCCAGCTGCCTTCCCGGAACCGGAGCCGGCGCCCGGGAGGCAGCCAGCTGCCTCCCGAGGACCGTCATCAATGTCGCGGAGGCGGCCAGCTGCCC

>NC_021658|10|4|3762660-3762973|CRT
CCGGAGGCAGCCAGCTGCCT	GCCCGGGATCAGGATCGATGTC
CCGGAGGCAGCCAGCTGCCT	GCCTGGGATCGGAATCGGTGCT
CCGGTGGCAGCCAGCTGCCT	GCCCGGGATCGGGATCGATGTC
CCGGAGGCAGCCAGCTGCCT	GCCTGGGATCGGAATCGGTGCT
CCGGAGGCAGCCAGCTGCCT	GCCCGGGATCAGGATCGATGTC
CCGGAGGCAGCCAGCTGCCT	TCCCGGAACCGGAGCCGGCGCC
CGGGAGGCAGCCAGCTGCCT	CCCGAGGACCGTCATCAATGTC
GCGGAGGCGGCCAGCTGCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_187345926.1|3758509_3759688_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_187345927.1|3773947_3774928_+|DUF3396-domain-containing-protein	unknown	unknown	gnl|CDD|371775
NC_021658.1|WP_080682720.1|3745209_3745653_+|transposase	unknown	unknown	gnl|CDD|379252
NC_021658.1|WP_020734671.1|3777054_3777831_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NC_021658.1|WP_020734657.1|3755390_3756992_+|glycoside-hydrolase-family-43-protein	unknown	unknown	gnl|CDD|350114
NC_021658.1|WP_187345925.1|3747031_3747370_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734660.1|3761594_3762479_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734667.1|3771254_3773933_+|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl|CDD|274542
NC_021658.1|WP_020734656.1|3754188_3755115_+|response-regulator	unknown	unknown	gnl|CDD|333815
NC_021658.1|WP_020734670.1|3776651_3776933_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734672.1|3777832_3778108_+|DUF3396-domain-containing-protein	unknown	unknown	gnl|CDD|371775
NC_021658.1|WP_020734666.1|3770476_3771253_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NC_021658.1|WP_049949500.1|3760431_3761370_-|metal-dependent-hydrolase	unknown	unknown	gnl|CDD|378401
NC_021658.1|WP_148313537.1|3742788_3743058_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044985798.1|3767292_3768429_+|PEGA-domain-containing-protein	unknown	unknown	gnl|CDD|285503
NC_021658.1|WP_148314786.1|3768320_3770069_+|hypothetical-protein	unknown	unknown	gnl|CDD|237537
NC_021658.1|WP_020734661.1|3763254_3766287_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020734658.1|3757149_3758391_-|response-regulator	unknown	unknown	gnl|CDD|223715
NC_021658.1|WP_020734665.1|3770073_3770355_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148313539.1|3748639_3751957_-|beta-propeller-domain-containing-protein	unknown	unknown	gnl|CDD|378255

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_187345926.1|3758509_3759688_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.16576e-84
NC_021658.1|WP_187345927.1|3773947_3774928_+|DUF3396-domain-containing-protein	gnl|CDD|371775	pfam11876, DUF3396, Protein of unknown function (DUF3396). This family of proteins are functionally uncharacterized. This protein is found in bacteria and viruses. Proteins in this family are typically between 302 to 382 amino acids in length.	4.38914e-43
NC_021658.1|WP_080682720.1|3745209_3745653_+|transposase	gnl|CDD|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.25414e-20
NC_021658.1|WP_020734671.1|3777054_3777831_+|serine/threonine-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	7.4726e-62
NC_021658.1|WP_020734657.1|3755390_3756992_+|glycoside-hydrolase-family-43-protein	gnl|CDD|350114	cd09000, GH43_SXA-like, Glycosyl hydrolase family 43, such as Selenomonas ruminantium beta-D-xylosidase SXA. This glycosyl hydrolase family 43 (GH43) includes enzymes that have been characterized to mainly have beta-1,4-xylosidase (beta-D-xylosidase;xylan 1,4-beta-xylosidase; EC 3.2.1.37) activity, including Selenomonas ruminantium (Xsa;Sxa;SXA), Bifidobacterium adolescentis ATCC 15703 (XylC;XynB;BAD_0428) and Bacillus sp. KK-1 XylB. They are part of an array of hemicellulases that are involved in the final breakdown of plant cell-wall whereby they degrade xylan. They hydrolyze beta-1,4 glycosidic bonds between two xylose units in short xylooligosaccharides. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. These enzymes possess an additional C-terminal beta-sandwich domain that restricts access for substrates to a portion of the active site to form a pocket. The active-site pockets comprise of two subsites, with binding capacity for two monosaccharide moieties and a single route of access for small molecules such as substrate. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	0
NC_021658.1|WP_020734666.1|3770476_3771253_+|serine/threonine-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	2.74224e-62
NC_021658.1|WP_020734667.1|3771254_3773933_+|type-VI-secretion-system-tip-protein-VgrG	gnl|CDD|274542	TIGR03361, VI_Rhs_Vgr, type VI secretion system Vgr family protein. Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.	2.64044e-167
NC_021658.1|WP_020734656.1|3754188_3755115_+|response-regulator	gnl|CDD|333815	pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.	1.62051e-20
NC_021658.1|WP_020734672.1|3777832_3778108_+|DUF3396-domain-containing-protein	gnl|CDD|371775	pfam11876, DUF3396, Protein of unknown function (DUF3396). This family of proteins are functionally uncharacterized. This protein is found in bacteria and viruses. Proteins in this family are typically between 302 to 382 amino acids in length.	3.13117e-12
NC_021658.1|WP_049949500.1|3760431_3761370_-|metal-dependent-hydrolase	gnl|CDD|378401	pfam10118, Metal_hydrol, Predicted metal-dependent hydrolase. Members of this family of proteins comprise various bacterial transition metal-dependent hydrolases.	2.31787e-77
NC_021658.1|WP_044985798.1|3767292_3768429_+|PEGA-domain-containing-protein	gnl|CDD|285503	pfam08308, PEGA, PEGA domain. This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteristic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	8.55341e-06
NC_021658.1|WP_148314786.1|3768320_3770069_+|hypothetical-protein	gnl|CDD|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	1.90153e-05
NC_021658.1|WP_020734661.1|3763254_3766287_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.43484e-69
NC_021658.1|WP_020734658.1|3757149_3758391_-|response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.98982e-49
NC_021658.1|WP_148313539.1|3748639_3751957_-|beta-propeller-domain-containing-protein	gnl|CDD|378255	pfam09826, Beta_propel, Beta propeller domain. Members of this family comprise secreted bacterial proteins containing C-terminal beta-propeller domain distantly related to WD-40 repeats. Jpred secondary-structure prediction shows family to be a series of 4 short beta-strands, characteristic of beta-propeller families.	1.11653e-31

Protein sequences

>NC_021658.1|WP_020734660.1|3761594_3762479_-|hypothetical-protein
MTKPSAPLKKKPAPRKPAAPPQAAAAFDKAAPEMNALERDALIPINIDIPRAVSQVLGVLPGLLALRPLIAERLPTHDAGLVDRLETYALAAWYAHLAWLSSGGSQSGLKPLLEEAAPLRANLLGDAEALARRGLVDAETVADIRAGNGHMDTASDLVALSALFSGSWSEIAGKTAATEDEVRRAGELGPELLAALGVREHGAAPGPSDAADKRARAFTLFVNAYDQTRRAVAYLRWNEGDVETIAPSLYKGRGGRGASPRDTDATPQEDPPAPPDAAPPGAPAPAPRQAESPG
>NC_021658.1|WP_049949500.1|3760431_3761370_-|metal-dependent-hydrolase
MDTDRHPCPWRAAPRPARAPPAPRPALLGAMARKESSMVTENAPLKPRKPPVSFEQGLTRHWLGGHMVPTHVANAVNLLFPAGERFFIRSVARYADRVEDPALRAQVKAFFGQEGHHAKAHERFFDLLRAQGYEIDRFLRAYERVAYDGIERVSSPELRLSVTAALEHYTAIMAEDALQAGTLDLAHPTARELLLWHAAEEIEHKTVAFDVLKIVNPSYALRLAGFAVATITLSMFWLSALLVLLAQELPRRGERGARAASTTARLPPLSHRSVLKGVFLRGIREYVRRDFHPSQNDNIHLARAYLAGIGAA
>NC_021658.1|WP_187345926.1|3758509_3759688_-|protein-kinase
MGVILLARDEQLQRDVAIKLLRPEQLDNAQMQARLLAEARAMARVHHPNVVEIYAFGEYVNAPYFVMQYVPGVTLDTHVHSKGGRLGLDEALSILDQACLGVSAIHASGIAHRDVKPSNILVGQALRVVVADLGLAKRIPRGDRVELAFSGTPAYLAPEVALGRQLDPALLPRIDVYALGVVAYYLLAGRLPFQSTSTVDLVMQHAYQPPIPPSELCLDLPPSFDAPVLAALAKEPDQRMASADALREALLDARSAMPAYARTTRVMVADDSPSFRTFLVSVLAQALPGAVIETAPDGAAALAAIEANPPSLGVFDLDMPGLDGIALTAAVRKLPRGDFPIIVATGTGGAADWQCLSRLGASAFLVKPFDAGQLITLARALVGVADEQKRKQ
>NC_021658.1|WP_020734658.1|3757149_3758391_-|response-regulator
MNDSEIKILVVDDDEVDHLVTRRLLREVSRTRYDVTWLSTSDEAIEALLAGGYDVCLLDYRLDARTGLDVVHEANRFGCAIPIIMLTGVGDEEIDMAAMSAGAADYLVKGRFDAQILERTIRYAIEHKRSQLKLKQYADTLEESNRQLLQMHEELAAKNAELVRLNEEKNRFVGMAAHDLRNPLGVILGYSDFMLMTHRRGEQASLLREDGVEIIQMIRSSSKFMLSLINDLLDVSMIELGKLNLDRKSTDVVQLVASNVALNMVLAGQKSMKLVVESDESVPRVDVDVHKLEQVLNNLISNAIHYSPPGTTIRVRVEGAPTADGGAAEVLLSVQDEGPGIAPEDIGKLFRPFGRARTVSTGGERSTGLGLAIAQRIVEGHGGRIWVESVVSKGATFFVALPVAPAPDAEAAA
>NC_021658.1|WP_020734657.1|3755390_3756992_+|glycoside-hydrolase-family-43-protein
MTSEPTFIENPVLRGFHPDPSILRVGEDYYLATSTFEWFPGVRLHHSRDLRHWNPIGYALDRRSQLDLLGNPRSGGVWAPCLTHAGGVFYLVYTDVKSWGGFVDAHNYYVTASRIEGPWSEPVALNRGGFDPSLFHDEDGRAWLVNMVWDHRPGNNQFPGIVLQELDLEQRRLVGERRWIFTGSGRGCTEGPHLYRRGDHYYLLVAEGGTSYEHAAVVARSRRIEGPYEVDPSAPLLTSVHDPALELQKAGHGCLVETTTGEWYLAHLVGRPLPGERRCILGRETAIQRVRWTDDGWLALDGAPRPPAPAVRVPAPRLPDHPFEEPPARDHFDRAALGVAYQTLRDVPDERWVSLRERPGYLRVRGRESPHSLHRQSVVGRRIQSLRCRVETCLEFEPASFQQMAGLMCLYDDESFFYALLGHDERAGRSIALLGSEHGRLTWLARPAACAAPRVHLRFELSGKDLQFSSSIDGERFDPLGPVLDASLLSDERTSRGLGFTGAFAALCAHDLTGSGLPADFDYLDYAELPQEP
>NC_021658.1|WP_020734656.1|3754188_3755115_+|response-regulator
MRSTGRVLIIDDDPSFVRLYESRLGEEGYLVETAPDAGAALAKLDQPGWDVVLLDQKLQGREGPDSGLDLLAEIGRRAPSAKTLLVTAYATPSAITRAFQEGVYDYLQKDEFFRILLLPKLRNAIEAVRARQLGELTDEETEATLREAWAAVESEADPNRKGKLLEDLMLLLVKTIPGFRQAQARRRNDVEEIDVLIRNESTDPFWANERTSYILIECKNWTKPAGVNELRSFMWKLERRYGRCRLGLFVAVGGFTSSFRDDLRGERKDDHLVLLLDRDDLRALVLASDRNACLKTFHERAVVELNGH
>NC_021658.1|WP_148313539.1|3748639_3751957_-|beta-propeller-domain-containing-protein
MLSAQARVMAALLLLYGQGCGGDDNKPDPQEQIPPEEEENENPPPEEEEPDPPEEEEPEEEEPEEEEPATPEGPTEFVSADDPFTEGYLGEEEEEEEEEEEEEEEEEETRELEEGDIYRVLGGGQLLNLNPYRGLQVINIQDPSNPKFLGQLQVAGTPVEMYVVGDRAAVLLNDWAGYQLKADGLTVERRTGGTVLFIDIADRTAPKILSQYPVAGRIMTSRLARGTSKTSLYIASNGSELEEFAPGQFHWVNKTLVRSFDVGTDALTERPGLELDDAVTAIHAEADVLLVARNRFSWSEEPSTISVIDISNTDGSMVERGSVTAKSFVRSQFHMDFRDDMLRVFSGPRWASGAPSYLETWNAADRDDITPIDSEDFGAEQSLYGAIFMDDRAFAVTYRRQDPFHAFSIDPAGNVTEESEFIVSGWNDFFRPVLGATRLIGIGVNDENGRRLAASLYDITDLTSADPLVARAEVDSAADGWSWSEANWDHRAFTVLDDAVEAVAPTGEPETGLVLLPFSASRVVDNTRRPFSGVQIFTFSGTTLTRRGLMEHGTPVRRTFRAEDIATANVSDEHLSLYAQGDLDAPTKLGQLELAPDYQKVFAFGSHRVRVKLPYDTYWMPYESRKLKAEVVPSTGVAQLEQPVATFDLPIDAQLYQVGDLLVSLTTTFENWVGKVAHIQVIDLSDPTAPRQAGTLDTGDLPAIGGYYGGGSSFPTVHAGRDALAFLRVIGHTEDLGVGWSCRTSAVQTPTCFGQEGCTYTAGERLCRRIGNDEYCNGGFAECTDHAGADTTCTPIEVDRNDIPGVTSTYCYEYVPRRTWAQIEISVVDLSDPDSPAVRPALSLPDDSETVNVLNDDGELYFNIKRSIGAPDDPRPHTQYFLTHLDLSNPAQPALDPGVNVPGEILAIQGTSIYARDKVWGQQFIETALARLELHEGLAYLQEYQQFPNRRVNAISIDGRGLPVLSHSLIWQPTYGIYYGWDPNQKLTTLSPLAAEEEPPPPPENENENENPTVPEFDQRSTVRLASWASLRHTTDMRALFEVPGGVLVISLEQPEAPKAQAFFQTWGWPEKFVANGEEVLFAAGRFGIHQLDRETVNLVPYLGE
>NC_021658.1|WP_187345925.1|3747031_3747370_-|hypothetical-protein
MPPPPSPAFPKKKKPAITAKEAMKAKVQARAGKKAAKPAPSPAAERATDHATAAAREEPRASAAAKPRDNGAAKPRDAAPKSVRRDQAATPEAPAKKPGLLRRLLNLFRRSG
>NC_021658.1|WP_080682720.1|3745209_3745653_+|transposase
MVAVAGAACGGGDKLFQTGSGAANSSGDGSGGSGNDFGSGGPGAHQYCGQLCKNANCQAIFSFTLAQDEIPVPVGLQLYLPEEWVNDLYRRRRVGVPDNVIFRPKWKAALEEVARVVRTSPAVMHWTSAFQAVLGSMNRREGSSLEM
>NC_021658.1|WP_148313537.1|3742788_3743058_-|hypothetical-protein
METGKKIDADFIRTNAGVRGKTGFSGHIEDAFSGGPLRPWSRVHGRDVTGHALDIGRRKIQTRTSPLRASHLPLVHDVGEGKGKRTGSI
>NC_021658.1|WP_020734661.1|3763254_3766287_+|sigma-70-family-RNA-polymerase-sigma-factor
MVAEGRRGEAPPAAIGRTGPPLLKPGTWFVRRFRVDRLLGQGGMGAVYAVTEKGQSWALKLVRSEFLDDPDQRRRLLREGEVLARMRHPNVVQVHEVGLTDNLTAWYRMELLDGVTFREELRRRRALSLPLACATVRAAALGAGHLHLFGGIHRDIKPENLFIVRGPRDVKLLDFGLARLSGAPDTLDAQTHGSPLYMAPEQIRDEVPTPATDVYALGLIAYEAIAGFHPFGDARAAGRVDALFAKHLNEVPPPLTRVGVPEEISDVIARAINKVPRERHRDGLAFADALWDAFLAMRDAPSTRDTNPGEPEISEVLRWGNEQAAATTGPAASDRPRASVERAAVPAAAAAGSPGGAATRLLPRDPQAGRQAGGEADPGQHGTGWGMTERLPERLRDPSCVAALAQRAPDPPLEQAAAAWVPVEHTVPLPRRAPVAGDARAGARPPAGGSHASTARAAAPAGPVAARPAAASARGATGARPRARITPRTLAIGLSLGVVVSLLLLDVILRLQSAPAAPSPARAIDAPPPTPASGAPLARAAGPAAIEPPAATGTVEGAGAAAPREAPPADGDAGARQSEGSTAPPTARPRRLPYRRRSRRSPGRRPPRRGRGGGRSSETPSSMTSSWSSGLAGSGVRPGTPRCRRPGSMFMSNPRRIAGQLVGEGSGRRVPAPPWTVTREVYDGHEIVRVRSRAGGGGGARAGAVPREAVAGAHRAHARGGARADVDAPVSGRAARVDPAAAAARREPRDRAGRRARQQGGSRARRSPGIRATPREEGMSRDRKGPPRPLTPEQQALVVGAIDLVRARVAELAPYARPEEREELIAWGYWGAVDAASRFSPARGTRFTTYAYAFIAGEILDCLKRERKVRRLMRAASLAARTFVAETSDRFDVIWDDEATNTGKLADYAMKLVATMVLGIVEAGDSLDDVAIDVEDRRWAIGHVRDVYAALGDADRRLYALYYVDQRPMHEVAAELGVSVSTARRRHDALLDRVTAALVERGVTALPPRG
>NC_021658.1|WP_044985798.1|3767292_3768429_+|PEGA-domain-containing-protein
MKARARRARAAGWLVLVVGALAVAPTAARAQGEQGAPAGAQPAPAVAQPAPASAEAAQASREADAAFARGKELYRLGKLDAAYEQYRTAWSLKQSYDIAANLANAELQRGMKVEAAEHLAFCLRSFPATGNAAQHEQVRAQFRAVRKEVGSIVVKANLDGAEVSFNGTAVGRTPFRHEVFVKPGTVAVEARLAGHEPARLTLEIPAGEVNTADLILLPPRAAERPAPPAPAPPRAEAPAPGPREGADTVGPRPEVLIAGGAVAGAGVIAGVILTALAVGRDGDADEQRDALVREGGPAACAVDSPRCAGLRDALEGAADLKNAALWTFVGAGAVGLATGAYALWGGGAPRQGVAAARAVTAAPVVTAGGGALLIRGTW
>NC_021658.1|WP_148314786.1|3768320_3770069_+|hypothetical-protein
MGRRRAAPGRGGGARRDGGAGRDGRRRRALDPGDVVKGEAGREEERRMRHWRGLMGITAVAFGAAMVPGTGCVFGVDYSDCAEFPGAVCGGGTGGSGGEEPPDPCEGDPREDPSVVSEACGVFAQAGAEEGGEGTRQRPYGSLQAAIEKAAAEGKRVYACAEGEAAFEESVKVEAGLEVLGSFDCAGWVLEAGKKSAIRGPADQVALTLGDGAEGARVEGFAIRAADAKQDGGSSIGVVVAAVEAELAEVEVTAGNGKDGARGTTPEEAPVAGASAEAGSASNACVAENAVLGGAAGVTSCEDGETAGGRGGLGGSGETDEGNGQVGEDGGPVPEENPMRKGLGGVGETASQDCERGNDGKSGTAGPAGIGGTGMTLALTGLSGGDGDRGKTGGRGQGGGGGGGAKAGLFCKLGPDTIDGVGASGGGGGAGGCGGKGGGGGQAGGSSVGIVSLGNRLKLTGVTIAVGKGGNGGAGAAGQSGAAGGNGAAGGTASGTAPSKAGCDGGKGGAGGPGGAGGGGRGGYAVGLAYAVTPSEAPAVQFSAGTAGTGGNAGPGGAMENAGAPGSEGSCWDFAKRSPCGG
>NC_021658.1|WP_020734665.1|3770073_3770355_+|hypothetical-protein
MRASKTRTQHEVLLSMLADDADVQRALVQMRGWAEKLAAAEIAAEQEAEAEDHEAWVRAVPAAWEADKHRSLGTAVLVLVILCGVALVALRLR
>NC_021658.1|WP_020734666.1|3770476_3771253_+|serine/threonine-protein-phosphatase
MYPQLAIEAAAQSDVGRRRSRNEDSFAALPYLGLFMVADGLGGNAAGEVASRMAIEVVKSCFEEEGDLEDTWPYGAARPRDRDEVRLVLSVRRANRAIYEASQQKDEMRGMATTFAGVLLGPGMAYIAHVGDSRVYRMREGKLERLTRDHTLLEELLRDGDGALETLEALSDRASAVTRALGCDESVAIESRVEATAPGDVFLVCSDGLWGPVPEERIAGVLREHGELSLAASLLVDLANELGGPDNVTCVLARLGGG
>NC_021658.1|WP_020734667.1|3771254_3773933_+|type-VI-secretion-system-tip-protein-VgrG
MRGGEVLRLSLSLASGEALRVERVAIREGVSSLFTVEVEAVSPEPCVDLEAIAGQPAALRIEAGEGSGLHGERVWSGVCSHVRQVHALEVRGGELGVSTYALTIVPALWRMALRTDYRIYQHQSVPEIGRAMLDAWGLDATWLVDEKEHPRLGYKVQYGETDLDFFHRLLEEAGIAYALLDDGERSRLVLADALHQSAPRRDAPIAYVDQPLDVRAHAWVTRVAVEQHARTGAIVLRDHDFQRPAWALLGPARSAGCTDARTERYRYQPGASMVEGGRDGAASHDDRHAARLAARALEAELTGACSISFQTNTLDLRPGTVFAVEGHPRPELDTRLGLLVTSLWIEGSARGSWSVSGTAVPASEPYRPARRTAKPIVHGMQSGVVVGPSGEEIHTDTHGRVRVQFPWDRLGGHDEHSSCWLRVCQGWAGAGYGLFALPRVGQEVLVAFLEGDPDQPVVVGRLSNALNPVPLKLPEERTQSLWRSASSPGGVGFNELRFEDRKGAELVALRAERQLRTEVGRDEALVVRGSRAKSVGGDESARTEGRAVAYVGKDAHVTVDGELRERVGGTRSLTVDGDRHERVGGVAALEAGGTIHLKAGGAIVIEAGDVTLRGPGGFVRIDASGVSIDGGAVKIQQGGAPGGAPAARPALPLVPAGALMRAEPVRLPLLGFAGGLPPMQAGGLGGGGGPLTPEEGAVCGFICRCMEERLRQQCVTRQIRTLEDASAHTSPLKAEVPYDMSKDPPEPIMSKNDPRRATRSSPKGSRIPDVVVVKDGTKPPTQDNIKEVIEVKFPPDKLKDLQRADYVVIAGRAPFVELGPERCGCPPQNKPQPQEITTGDVAEVAALSLLVLALVLDDAVPGGQADDVAIPPAVARILSKLAPLLRGPVSVP
>NC_021658.1|WP_187345927.1|3773947_3774928_+|DUF3396-domain-containing-protein
MSEEVKEMMEVLDEHLVVRDREGRPVLQVALLATLYFENAYKREVREAVVSCCDDYFRRCDHRLRWALNPDTELMEPFDNGRGSNPRSWLVGLGEDEGFSLIYHGAEYDRGASAFYASALGLPRRPFVELGFFRMAFPLLWFADSSESLSEVMLEVCRKLKPVSGYAGIGVVESPDSSISNLYEPVVYDWAQRFPGLEVDYPICHLSWLRKGRGGGGGIKGVDWLTVLGERWIVEMGGVDKIEADLGALDSRFVIRWFEGGVLIQAGPHPQLGDATRNVWPELYVKLSKYLRPIRITEHRPFHYAGPGLRFDLDRSEAWLRRFDDR
>NC_021658.1|WP_020734670.1|3776651_3776933_+|hypothetical-protein
MRASKTMTQHEVLLSMLADDADIQRAIVQMRGWAEKLAAAEIAVEQEAEAEDHEAWVRAVPAAWEADKHRSLGTAVLVLVILCGVALVALRLR
>NC_021658.1|WP_020734671.1|3777054_3777831_+|serine/threonine-protein-phosphatase
MYPQLAIEAAAQSDVGRRRSRNEDSFAALPYLGLFMVADGLGGNAAGEVASRVAIEVVKSCFEEGDDLEDTWPYGAARPRDRDEVRLVLSVRRANRAIYEASQQKDEMRGMATTFAGVLLGPGMAYIAHVGDSRVYRLREGKLERLTQDHTLLEELLRDGDGALETLEALSDRANAVTRALGCDESVAIESRVEATAPGDVFLVCSDGLWGPVPEERIAGVLRGHGELSLAASLLVDLANEHGGPDNVTCVLARLGGG
>NC_021658.1|WP_020734672.1|3777832_3778108_+|DUF3396-domain-containing-protein
MRGGDMRGGEVGALNSRFVVRRFCRGILIQAGSRPQLGDAERNVWPELYVKLSKYLKPIRITKHRPFQYAGPGLRFDLERSQAWLRRFDER

Crispr_ID: NC_021658_11

• CRISPR_ID: NC_021658_11
• CRISPR_location: 4114756-4114862
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NC_021658_11

Consensus_repeat	Method
GCGCGTGTCCTCGTGCGCCCGCGC	CRISPRCasFinder

spacers of NC_021658_11

>11.1|4114780|59|NC_021658|CRISPRCasFinder
CGCCCGCAGCCAGAGCGCAGCCGCCCCAGCCGCAGCCGCAGCCGCAGCCGACGCGCGGC

CRISPR arrays and Neighbor proteins around NC_021658_11

CRISPR arrays

The CRISPR arrays of NC_021658_11

>merge|NC_021658|11|4114756-4114862|CRISPRCasFinder
GCGCGTGTCCTCGTGCGCCCGCGCCGCCCGCAGCCAGAGCGCAGCCGCCCCAGCCGCAGCCGCAGCCGCAGCCGACGCGCGGCGCGCGTGTCCTCGTGCGCCCGCGC

>NC_021658|11|8|4114756-4114862|CRISPRCasFinder
GCGCGTGTCCTCGTGCGCCCGCGC	CGCCCGCAGCCAGAGCGCAGCCGCCCCAGCCGCAGCCGCAGCCGCAGCCGACGCGCGGC
GCGCGTGTCCTCGTGCGCCCGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_080682134.1|4100349_4102062_+|VCBS-repeat-containing-protein	unknown	unknown	gnl|CDD|379232
NC_021658.1|WP_187345939.1|4098624_4100106_+|IgGFc-binding-protein	unknown	unknown	gnl|CDD|379980
NC_021658.1|WP_020734913.1|4119015_4119501_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187345943.1|4118081_4118783_-|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl|CDD|381594
NC_021658.1|WP_187345941.1|4112498_4113740_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949514.1|4123384_4124116_+|heme-exporter-protein-CcmB	unknown	unknown	gnl|CDD|225260
NC_021658.1|WP_044985836.1|4108309_4109641_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NC_021658.1|WP_187345942.1|4115207_4116404_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
NC_021658.1|WP_020734910.1|4116482_4117868_-|KamA-family-radical-SAM-protein	unknown	unknown	gnl|CDD|224426
NC_021658.1|WP_044988232.1|4096893_4097922_+|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl|CDD|376764
NC_021658.1|WP_020734914.1|4119540_4120569_-|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NC_021658.1|WP_080682135.1|4121444_4123376_+|biosynthetic-arginine-decarboxylase	unknown	unknown	gnl|CDD|235427
NC_021658.1|WP_020734918.1|4125640_4126270_+|hypothetical-protein	unknown	unknown	gnl|CDD|277320
NC_021658.1|WP_187345940.1|4102546_4103941_+|thrombospondin-type-3-repeat-containing-protein	unknown	unknown	gnl|CDD|275365
NC_021658.1|WP_020734915.1|4120841_4121219_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148313573.1|4103838_4104285_+|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NC_021658.1|WP_020734917.1|4124156_4125431_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|273584
NC_021658.1|WP_148313576.1|4109861_4111508_+|hypothetical-protein	unknown	unknown	gnl|CDD|287142
NC_021658.1|WP_020734906.1|4104644_4108298_-|hypothetical-protein	unknown	unknown	gnl|CDD|223686
NC_021658.1|WP_148313578.1|4114345_4114594_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_021658.1|WP_187345942.1|4115207_4116404_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	1.3e-41	137.2	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_080682134.1|4100349_4102062_+|VCBS-repeat-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	5.2463e-07
NC_021658.1|WP_187345939.1|4098624_4100106_+|IgGFc-binding-protein	gnl|CDD|379980	pfam17517, IgGFc_binding, IgGFc binding protein. This domain is found at the N terminal of human IgGFc-binding protein and has been shown to confer IgG Fc binding activity. It may play a role in immune protection and inflammation in the intestines of primates.	1.41112e-91
NC_021658.1|WP_020734914.1|4119540_4120569_-|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.10678e-06
NC_021658.1|WP_187345943.1|4118081_4118783_-|transglycosylase-SLT-domain-containing-protein	gnl|CDD|381594	cd00254, LT-like, lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	1.49525e-46
NC_021658.1|WP_044985836.1|4108309_4109641_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	9.08201e-07
NC_021658.1|WP_187345942.1|4115207_4116404_+|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	4.49443e-37
NC_021658.1|WP_148313573.1|4103838_4104285_+|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	3.24052e-44
NC_021658.1|WP_044988232.1|4096893_4097922_+|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl|CDD|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	7.26489e-61
NC_021658.1|WP_049949514.1|4123384_4124116_+|heme-exporter-protein-CcmB	gnl|CDD|225260	COG2386, CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component [Posttranslational modification, protein turnover, chaperones].	9.87269e-24
NC_021658.1|WP_020734918.1|4125640_4126270_+|hypothetical-protein	gnl|CDD|277320	cd00841, MPP_YfcE, Escherichia coli YfcE and related proteins, metallophosphatase domain. YfcE is a manganase-dependent metallophosphatase, found in bacteria and archaea, that cleaves bis-p-nitrophenyl phosphate, thymidine 5'-monophosphate-p-nitrophenyl ester, and p-nitrophenyl phosphorylcholine, but is unable to hydrolyze 2',3 ' or 3',5' cyclic nucleic phosphodiesters, and various phosphomonoesters, including p-nitrophenyl phosphate. This family also includes the Bacilus subtilis YsnB and Methanococcus jannaschii MJ0936 proteins. This domain family belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	0.00495094
NC_021658.1|WP_187345940.1|4102546_4103941_+|thrombospondin-type-3-repeat-containing-protein	gnl|CDD|275365	sd00001, TSP3, Calcium-binding Thrombospondin type 3 (TSP3) repeat. TSP3 repeats of the vertebrate thrombospondin (TSP)-1,-2,-3,-4 and TSP-5/also known as COMP (cartilage oligomeric matrix protein), and related proteins. These short aspartate-rich repeats are a continuous series of calcium binding sites that can be divided into two sequence motifs: N-type and C-type. N-type and C-type motifs are distinguished by their sequence length, calcium ion binding, and their interactions with water molecules. C-type motifs are higher affinity binding sites compared to N-type motifs.	4.46894e-06
NC_021658.1|WP_020734910.1|4116482_4117868_-|KamA-family-radical-SAM-protein	gnl|CDD|224426	COG1509, KamA, Lysine 2,3-aminomutase [Amino acid transport and metabolism].	1.43542e-116
NC_021658.1|WP_020734917.1|4124156_4125431_-|(2Fe-2S)-binding-protein	gnl|CDD|273584	TIGR01372, sarcosine_oxidase_alpha_subunit, sarcosine oxidase, alpha subunit family, heterotetrameric form. This model describes the alpha subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason.Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines].	8.0851e-24
NC_021658.1|WP_148313576.1|4109861_4111508_+|hypothetical-protein	gnl|CDD|287142	pfam10131, PTPS_related, 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein. This domain is found in various bacterial hypothetical membrane proteins, as well as in tetratricopeptide TPR_2 repeat protein. The exact function of the domain has not, as yet, been established.	0.0003246
NC_021658.1|WP_020734906.1|4104644_4108298_-|hypothetical-protein	gnl|CDD|223686	COG0613, COG0613, Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only].	7.42679e-05
NC_021658.1|WP_080682135.1|4121444_4123376_+|biosynthetic-arginine-decarboxylase	gnl|CDD|235427	PRK05354, PRK05354, biosynthetic arginine decarboxylase.	0

Protein sequences

>NC_021658.1|WP_148313578.1|4114345_4114594_+|hypothetical-protein
MQAWMKSTMASATSSGDGEKIAAALQYVAGKPPPGMGSWGAISKAGAAKAKAGDIDGAKASCKQCHDLYKEQYKKTMRDRPW
>NC_021658.1|WP_187345941.1|4112498_4113740_+|hypothetical-protein
MLPELDACADGIDNDCDGTVDNPPDEDGDGWTICEGDCCDSSLDACGPPSLMNPGAFEVADNGLDDDCDGAVDNASPCDEGLASDSATALDYAKAMDLCATTTTSRRTWGVLSASFRRADGAGAPVAAQRSIRRGFGSGILPLRGARLAVLSTGVAAAQASPNNTRPSFAPFQGGQDMGTSSGMPADWLEANGERLPNTPGCPEPLGGTTAHDPVMLRLRVRVPTNASSFSVSTFFLSSEYPEWVCSRFNDFFLALLDSTFEPFPGEAENPDDKNLAFYDPPPAGGSVYPLGVNLAFGDTGLFTQCVNGPTGCGGGAKAGSTTTCTGVGQLLGTGFDITRPPAQIEGEPGWCGTSERAGGGTGWLIMNGNVVPGEIIELRFVIWDTNDPWNDSVALLDNFRWSAFAATPGTRD
>NC_021658.1|WP_148313576.1|4109861_4111508_+|hypothetical-protein
MEMPGSSPPDSALTPAAAPPRRDAAAEPPASRRWPGWASDRAFVATFALLAVAAIVPIWRVRFLPLLDLPNHLAAVHIWHHFDEPWTRYRDFYELSLRPAPYGAYHILTHLLAYAVDLEVANRIVLSGYVLGIPAAALGWAHRTRRSPWLSLLTFPLAFSLSWACGFLPFLVGIALLLAGVVALDATLERPSPGRAAAVALLSVGCGLSHPLILFGYYVCVAALMLCYLPRWSRIARALPLFAPAAALLAWQLVAFESPMVDLRSGPRFQGAWVPWHEMLRSFPEYTLDSVSGELDTRLFWVLLAAASLLALWSLARRFGLLLPAGDAATPAGSPLGRLHHHRSLVLCAAMVACYFLVPLHLARPFDWWFVSGRFSPLICFFGFLAIQAPLRGRARLLMAPAAAVALVLPLHLSEKYASFDERIEPFARLVARVPPGAEVLFVSLPPRTDEALIIEGTNHFSSWVQVMRGGFSADGWHNVGFPFKLKRRLPAPPSNRGEWFKPDVHGVAYDYVILRNERPERPVFTAAHTSFRRIERDGAFTLYERTR
>NC_021658.1|WP_044985836.1|4108309_4109641_-|hypothetical-protein
MRHLACVAGGAAVLLALSSSRAQEPAAEAPAAEAPAAPAPTEAQAPSGEPAGEPERAAPPAARPTAPVSQPPPREAQAQGSPAPARGDLLSPGFRERMRAALGPLEVAPIALLALQAAPYVGDDALSQAGDSAEQPGFRLRRARVGLRGDVAGLVRFAVSTELAGGDEGTARIHEAWAGVTAERALEVYAGARTVPFSRSAMLGAGDGALTERPLAVRAMAPFTQVGIQAEGHFQDRAFSYHAGVYNAFQRADRFYAGHSESLAPLGNRFEGIAFAGRLATEPRGPLGRTLQDVAHSPLRLGVGADGFFSNGGARTLYGASADVLLHAAGLHALGEVLWTGASPKSVPTQPISQVTSVSSLALVFEAGYMLVARQLGVSGRVEWIDPNIDVDDEGDNLALTGGVSYHAYDDLLKAQIDYTHREELGGLSLANDAVILQLQLSL
>NC_021658.1|WP_020734906.1|4104644_4108298_-|hypothetical-protein
MRRTHRWFTRVALLPLAAAALAAPALPSCGGDRLLRAKQIEHRAELVGGPVAMADVGDFLLENDQIRVAILGGRDSPGPGIFGGAIVDVDRRRGRIGEEGGQGRDRFAEMFSLANLIVPDPTATDVSVLADGSDGAEAGIRVEGDGEFLFEAIGLLRAQEDLLGLFFPNVRSRIRFRTDYLLHPGDRFVTVRTVLLLDDRPPPGCEAPRSCEPCPDGYQQDPGGCLTCACSDVLPLDNATAPVSVLGGVLGDPADQAQEEAARRAGIVAGDFVFFGNQNDVFAPGAGFDEDTAVQDAWNAGRNSFSEPLTFDFVAAAGGDVSYGYFTRAQEGAAPSVVNVPLFASAATAFVSASRSCLYSEGDDAACDAHRAFSYERYLAVGDGDIASVTDVMHRLRGTETGTVHGHVLWESTLEAAPNARVFVFSDPDPSRPFGSLDELVAANREARGDVGLINEIDADVGLDPSEDGDFRGALPPGSYVLVARNAAGTATSAPVRVRLRAGEQVAVSPRLPTPATVRYRVADEAGQRMPAKLAFISLDDAGRRLPGDGRRRVYLGDGRLGNGNRAIEVTATGEGEVEIEPGRYQITVSRGIEYGIYVERDVTLAPGRAFQLDATLVREVDTSGWMSADMHLHSRPSFDSGMPLPRRVATVAAEGVELAVSTDHDVETDYQPTARALELAPHLATAIGAEITTLEQGHFIGFPLKYDELDVPTHGAHDWTCEPGGTILDAIRASGDGTVEPLTIVAHPRDGFFGYIEQLGVDTYTMDRTPTFLEENNPVFRTASCAFDAMELINGKRFDLVRTPSVAEVVDWNRCLARLNAARGAGEIEAACPEAAGWLRAPCAAPGGSAPAAGGASGSPSDAAVAVAVADCKRRARTELAWALMKRILARTPDEQEKNWGFAGASPDSQELCGPAALGDAPVAAEARDEPCTFRAGQVDDYFRYLERGFLPAQIASSDSHDASKEPGFPRTYFRSATDSPAALATPAAVESLRGAHAFTTYGPFVRATIGGRTYGEVAGASAGEPLELLFDVQTASWFGVDRVEIYLNGRMIRLLEPEMPPSALVDVRGKVTFTVPERDSWVVIIAMGLEDRNLMSPVSLDVPFGEIQLSRLASDGFGRIPAISALFAPTPTVPDWSPVPPYAVTNPIYIDVDGNGRYDAPLPRPDFCSRPCDPAVLDPEQCPAEQDCLLEEQVCGFPIPGKCDHRRPALGHHDD
>NC_021658.1|WP_148313573.1|4103838_4104285_+|OmpA-family-protein
MPEEAGQVVVDEPEKNGCPYYIRRITGSAEIEIMKQVEFEFDSSRILPQSYPILDEVVRLLKANPEIKLLSIEGHTDNQGTIDYNDRLAHNRAIAVRVYLVNKGIQGERLTSVGYGSRRPLVANDTPEGRQRNRRVEFHIKSQSIEGR
>NC_021658.1|WP_187345940.1|4102546_4103941_+|thrombospondin-type-3-repeat-containing-protein
MMDRRNLPGGKPRRPSRLRCALTAAALAAPALVALAPSAARAQDRTFYLDRLRMAGAPDDGIGVWRPHMGEKTRLFGQLGLGVSVHPLRNDNYVDNLAVEEQLEGEGPVTSQLITYLSAGVEILGRGALQASFPIVVFQDGNQTCHPDRTLGLDQCVNLKTATPMDLRLDARLVALELDERRFRLGLTAAVFVPVGNVYSFGGDRTVSSAFGLGAEYDFKDFFVTLNTGVAIRPPVRLHELRVGTELTYGVGGYVPLVDDTIRVGAEIFGSFGLREETLGELDASPIEWQLNGRMALTKDKALYAGAGVGTRMSGGYAPDFRGVAVVGYSFSIADSGTRSPGFNYVIEQEKDTDGDGYPDVIDLCPQDPEDGKQPKPADGCPDMPDRDGDGIPDVVDKCPDDPEDKDGIDDRDGCPEEDADQDGIPDAEDKCPKKRGRSSSTSPRRTAARTTSAGSPAPPRSRS
>NC_021658.1|WP_080682134.1|4100349_4102062_+|VCBS-repeat-containing-protein
MVDIMGMRWSTVVFGAEVGWIACIGLLVGCGKILGLNEFVDAPGGTVASSSGVTTSGGGSGLGEPPTVPVLRLPRNDAYLGAQRKTGSNRPRFVWEASTSPSGASIEYELQYSASPDFIDAVSSTTEFTEYQPDEDLAIALLPPVGRRYYWRVRACAQGACSEFSRAWWVNVGRTKCDYNADGYDDVAISAYGRSPTSSAIYFYFGIPGARFGSEDDGIVFSPFGANDGFGISLSCAGDVDGDGYADVLVGAPYRDTAFVYRGSSSNRFGSDYVRIDGNSVEGMLGPYMASAGDVNGDGFADVIVGTSERSVLIASLYLGGPDDLDAPINLELGEPVEDLGNAISFVSSAGDTNGDGFSDVVVVFHTVDRDIVRLYHGNPGRGFDSAPAIELVDPSGHTKFVSSFDAAGDINGDGFGDVIIGARESNRAYIYLGGSRGLEPTPSLTLVGNESFGATVAAVGDVNGDGFDDVAVADRSPKVLLYLGDGELGVEEPSAAIYGDAVEDRTGQRLGTPGDVNGDGYSDFFVAATEENVVHFYYGRSVVMSPLTEDVSIAQPSGDREFGFAVAHR
>NC_021658.1|WP_187345939.1|4098624_4100106_+|IgGFc-binding-protein
MQRTQAEGACFAAFVANTWEKEVHISVERDGTVLPVEKFAFVPRGQGSNVTYEPYVESEGLAAGEVAVLFLSRSRTGGLIRCPKDPAVQDETGIPKNTADTEFTGRGSAFHITTDYPVVAYQIVPYGGGLTSYTSATLLLPTSSWDTNYVAVNAYPVSELTPSGLPALEIVAREDDTNVTILPNADIEGAGPTNAPIVAPASKGMPVTYTLKKGEFLQIGQRAELTGSPILSDKPIGVFGASSCMNVPLDVADCDSAHQQIAPVRATGNEYVAVRYEGRTGGDGQTGDEEAPPWRLVGMVDNTELRWEPSKPDGAPDTLELGEVREFRAAGPFVVRSQGGQNPFYFGGYMTGGENYSEQGDPEWVNVIPPSQFLNYYVLFTDPTYPQTSLNVVRTPSQLDGSFADVTLDCLGTITGWKRIGEYEYTRVQLVSGDFEGNGDCVNGRHVMSSELPFGVTVWGWGTTNVTRLVSYAYPAGAGFQPINQVTIPPVPR
>NC_021658.1|WP_044988232.1|4096893_4097922_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MVVEWLLGGVMVAALVLYALLGGADFGGGVWDLLASGPRKQEQRALIERVMGPIWEANHVWLILVVVLLFTAFPPAFAAISVALHVPLTLFLVGVVFRGSAFSFRSYDSRRDHRQKRWGLLFSLASVIAPVLLGMIVGAVASGRIRVASGVVTSGFFAPWLSLFPFMVGLFALSLFGFLAAVYLTNEATEPALVDDFRLRALVSGCVVAALALACFGASFEGAPLIREGLTDHPITWPLHVTTGIAATAAFFGLWTRRFRLARFAAAAQVTLILLGWAASQYPYLVVPDVTLAGAAANPRTLRLLVWVLGVGFVLLFPSLYVLFRVFGSGRAGAASDSDDAH
>NC_021658.1|WP_187345942.1|4115207_4116404_+|WYL-domain-containing-protein
MRPPPSVRPPAAPARTDAPPPAAASKRPPAPEDDDDEDDEDDAKGGPRRGRPRGPFTQHRRLDSLRSLLQKHPAGLTIYDLARELNVTPRSLRRYLVEVKRELDLVSVATRPGGPRLWRLSPSEAPRRVEVRRTQAYALLAARRLFEPMRGSTLFEEIDLAAQRLLGVARRPGRGPNAGVADARLEERFLYLPFAPKDYAARTEELDDLFQSVADLRPLRCRYRRSRDGREERVLIHPYALVLYKDAIYCVGLHVSRGEVRTFLLDRMRDTECAVTERFELPPDFSIDDYFQGQFGIWRGGEPRRVVIDFDERVTEFVRTRKVHPSQEITQLPGGGVRLTMHIGDMTELATWVLGFGETARVVEPPDLVDRVKRELAGALARYAEPPPAEGSGQAEGP
>NC_021658.1|WP_020734910.1|4116482_4117868_-|KamA-family-radical-SAM-protein
MTTTSSLIELTKRSPDIAPLKQPVDPASLQHAKLLEVPDFRRIPAYADVTDEQFMDHRWQAKKSITRPDKLLDTLRGMVSDDFIRDATEGFAHAPMSVRVSPYMLSLIDWSDPYGDPLRTQFIPLASRFLPDHPKLGLDSLHERADAPVPGLTHRYADKALFLPLDTCPVYCRFCTRSYAVGIDTEEVEKTHFKVDEERWKRAYAYIASRPELEDIVVSGGDAYNLRPEQISAIGEALLGMPNIQRIRLATKGPAVMPQKILTDDEWIDAVTRTVELGRRLHKEVVIHTHFNHPNEITGVTRDAMNKLFERGITVRNQSVLQRGVNDTPETMKLLVKRLGHLHVHPYYVYIHDLVRGVEDLRTTLATGLMIEKHVRGSTAGFNTPTFVVDAPGGGGKRDAHSFEHYDRTTGISVFEAPSVKPGQRYTYFDPIDQLPPEGRARWADPAEHQKMIDEALRASR
>NC_021658.1|WP_187345943.1|4118081_4118783_-|transglycosylase-SLT-domain-containing-protein
MLSREMPVQSTSGSSVRVPLRALVAALGLAALALHPGSALADIFTYTDADGTVHFSNRAAGDARFKVYIKGDGRRPGARPGVAPVAPSDKSLERFSRYDTWIRQAATLYQIPEELVRAVIKCESDYDPRAVSPVGAQGLMQLMPETALRMQVRDPFDARENIFGGTRYLRILANLFNGDLDLTIAGYNAGEGAVMRYGGIPPYEETQAYVTRVRTYYARYRTTRDTTVASIEP
>NC_021658.1|WP_020734913.1|4119015_4119501_+|hypothetical-protein
MEIGWRHVLAGVAALFILFLVIKMRPARRRRDALSAEVQAARERARRASSPRERAEALCDAGVQAMRGGRRVTAAVGFFVRAMRADPASARVIELASGALARRRPRLLETILWRRLAVLPWEGEHRDAARAAAVGLEALYRREIRDRSRAEIMRKLTRTLG
>NC_021658.1|WP_020734914.1|4119540_4120569_-|CPBP-family-intramembrane-metalloprotease
MVQGAPMLNLGSWLVAHVDRLRPLRPPSDASARLAEPSSALASTLLKALFPVAAFIALAPVLWLFFRRTWRELDVEAHEHQRRTLAAGGYDRRPAVLFTITAVVLMLQQYYGGRAVYDEHIRPWLRELELAQTLSPAGVIVPISLRRYDELYSYVWWSFTRVFGYVAIPMVAWKLCFPRDSLLDMGLRVRGLAQHAWIYLLCLAVVVPAVFIVASAPDFGSYYPFYKQSSRSWFDLIAWEAMYFAQFFALEIFFRGFWLAGLRHTLGSGAIFAMVVPYCMIHFGKPYLEAAGAVVAGIALGSLAMRTKSIYSGFLVHVTIALLMDLVALSNRGALPRSFWGM
>NC_021658.1|WP_020734915.1|4120841_4121219_+|hypothetical-protein
MASKNPLAIVKERFGDKAKLVEALKGLANEDLWLGRVSTDRGGSKGLEHVSNAKLLRLHATFSTVKEKFGTRAKLIDETLAVLNRSKDQGYRKRLEAYPVPRLYDLYQSASKRAKAASATPKAQA
>NC_021658.1|WP_080682135.1|4121444_4123376_+|biosynthetic-arginine-decarboxylase
MSSAHETETGVWTTEDAKSLYMIDRWGRGYFDVSPDGNLTVAPLQERGSKIAIRDVVDAALEQGLRTPLLIRFQDLLHHRVRALNEAFNKAIAESKFRGTYRGVFPIKVNQLREVVEEILDAGKTYHYGVEVGSKPEVFAGLSVHHDPESLIVCNGYKDENFIRTALIGRKLGKKVILIAEKLSEVRMITRVAKDMNVEPMIGLRVRLLTEGAGKWKTSGGENAKFGLSTAEILAAIRIMDEAGMSASFKLLHFHIGSQVPDILIIKRAVREATRYYAKLRKMGQRIEYIDVGGGLAIDYDGSRSTFHSSMNYSVEEYARDIVHNIADICDEERVPHPNIVSESGRAIVAHHSVLVVQAFGSIEKTPMSPIDIQTEEHKLIQNLLYIKDNLSGPNLGESWHDLLQIKEEAQKMFELGLLNLDVKARVEILFWEIAEAMEKIASELDPEEVPDDLGELRKQLADQYICNFSVFQSLLDHWALGALFPIVPIHRLNERPAADSTLVDITCDSDGKVSKFIDLNDVKDTLPLHPIVGDQPYYVGIFLTGAYQDIMGDIHNLFGRVNEVHVFLDEDEESGYYIEETIAGNKIHEVLALTQYDNRDLVGKVKAQVDGAIKQDLLKPTEGMRLLADYERGLKDQTYLSL
>NC_021658.1|WP_049949514.1|4123384_4124116_+|heme-exporter-protein-CcmB
MLSETTAPAGPASLSRRRPGWARQAMLVARKDLAIELATGEIVTTSGFFAVLVAVIASLAFYAGQDAAERVAPGVIWVSVAFASVLALSRTWQREREDGALSGLLVLPIARSALFAGKALGLCVFVIAVEAIIIPAAALLFAVDLAKTGAGLALFCLAATPGIAASGTLFGAMTVRTRARDLVLASVLFPLLAPTLLAAVAGTRELFGGATLGELTDYVALMAVFDVVFIAGGIGLFDLIIEG
>NC_021658.1|WP_020734917.1|4124156_4125431_-|(2Fe-2S)-binding-protein
MFRRGRALRDPVTITLDGADVPAERGEPLAVALLASGRVTLARSPKLHRPRAPTCLRGGCDGCLARVDGVPNVMTCLRPAAGGERIEVQNVVGSREADLLRVTDWFFPQGIDHHHLMAGVPGLSGVMQSIARKLAGLGRLPSAPLPPEPAARLELDAAVIGAGPAGVSAASALAARGQRVALIDDGLAPAGSLAGAPRRAAELLARHPLDGVRVLCRHVAAGVYLGELLVAGDAGATVIEAPALVFATGAHDGVAAFPNNDLPGVFSARALCRLLACGVEPTGPVALAGEGFWADELASALGDRIAARIPLAALAAVNGISQVKSVTVRGAPFAQGSPTRDLKVVAVAVDAPAAPSFEVAAQAGARVEVDPRAGYAVRVDARGRAGDGVWAIGECTGAALDLDGLARAAALLADDVVAARGAAA
>NC_021658.1|WP_020734918.1|4125640_4126270_+|hypothetical-protein
MLWPMRLGVLGPAQGDLPALARGAQHLLDEGHAERVIYVAEDDALDRVVEGWAQSLVGVNPTEGALFDRAARCAAATPEQIDAFVASERARLRLKVLMSLPPGQRTIEILDGRVALFVFDKAALDEEDIVAASLLVFGKSSEPLIKKVGPRTFFSPGPIGSEGGRALLDDGQGGVRIEVINASGAVTAREIVGPPAAGPKLRVQGGSHG

Crispr_ID: NC_021658_12

• CRISPR_ID: NC_021658_12
• CRISPR_location: 4496540-4496628
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_12

Consensus_repeat	Method
TGCGCCGGGACCTCGCCGCCGCTGCT	CRISPRCasFinder

spacers of NC_021658_12

>12.1|4496566|37|NC_021658|CRISPRCasFinder
GCTCAGGCGCAGTCCCGCAAACGCCTATTCGTTGGAC

CRISPR arrays and Neighbor proteins around NC_021658_12

CRISPR arrays

The CRISPR arrays of NC_021658_12

>merge|NC_021658|12|4496540-4496628|CRISPRCasFinder
TGCGCCGGGACCTCGCCGCCGCTGCTGCTCAGGCGCAGTCCCGCAAACGCCTATTCGTTGGACTGCGCCGGGACCTCGCCGCCGCTGCT

>NC_021658|12|9|4496540-4496628|CRISPRCasFinder
TGCGCCGGGACCTCGCCGCCGCTGCT	GCTCAGGCGCAGTCCCGCAAACGCCTATTCGTTGGAC
TGCGCCGGGACCTCGCCGCCGCTGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020735170.1|4510565_4512347_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735151.1|4484010_4484994_+|hypothetical-protein	unknown	unknown	gnl|CDD|224662
NC_021658.1|WP_020735152.1|4486574_4488806_+|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl|CDD|223256
NC_021658.1|WP_020735163.1|4502983_4503412_+|hypothetical-protein	unknown	unknown	gnl|CDD|227311
NC_021658.1|WP_044988277.1|4495256_4496123_+|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|187578
NC_021658.1|WP_148313611.1|4485111_4486074_-|hypothetical-protein	unknown	unknown	gnl|CDD|237865
NC_021658.1|WP_187345957.1|4494493_4494652_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735159.1|4496649_4497354_+|iron-containing-redox-enzyme-family-protein	unknown	unknown	gnl|CDD|379634
NC_021658.1|WP_148313612.1|4490003_4490636_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-ligand-binding-domain-containing-protein	unknown	unknown	gnl|CDD|379883
NC_021658.1|WP_020735155.1|4490632_4491805_-|cobalamin-independent-methionine-synthase-II-family-protein	unknown	unknown	gnl|CDD|239427
NC_021658.1|WP_020735162.1|4501038_4502283_-|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl|CDD|182059
NC_021658.1|WP_020735150.1|4483237_4483867_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_021658.1|WP_020735169.1|4508409_4510095_-|family-43-glycosylhydrolase	unknown	unknown	gnl|CDD|350130
NC_021658.1|WP_020735156.1|4492245_4493703_+|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl|CDD|275079
NC_021658.1|WP_148313616.1|4506034_4506517_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314803.1|4512798_4514058_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270242
NC_021658.1|WP_020735160.1|4497754_4498594_+|UbiA-family-prenyltransferase	unknown	unknown	unknown
NC_021658.1|WP_020735165.1|4504326_4505697_+|tyrosinase-family-protein	unknown	unknown	gnl|CDD|365987
NC_021658.1|WP_020735153.1|4488902_4489928_-|hypothetical-protein	unknown	unknown	gnl|CDD|381626
NC_021658.1|WP_187345958.1|4498618_4500781_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366721

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020735151.1|4484010_4484994_+|hypothetical-protein	gnl|CDD|224662	COG1748, LYS9, Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism].	0.000547916
NC_021658.1|WP_020735152.1|4486574_4488806_+|excinuclease-ABC-subunit-UvrA	gnl|CDD|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
NC_021658.1|WP_020735163.1|4502983_4503412_+|hypothetical-protein	gnl|CDD|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	0.00357968
NC_021658.1|WP_044988277.1|4495256_4496123_+|NAD(P)H-binding-protein	gnl|CDD|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.10049e-55
NC_021658.1|WP_148313611.1|4485111_4486074_-|hypothetical-protein	gnl|CDD|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	1.98808e-08
NC_021658.1|WP_020735159.1|4496649_4497354_+|iron-containing-redox-enzyme-family-protein	gnl|CDD|379634	pfam14518, Haem_oxygenas_2, Iron-containing redox enzyme. The CADD, Chlamydia protein associating with death domains, crystal structure reveals a dimer of seven-helical bundles. Each bundle contains a di-iron centre adjacent to an internal cavity that forms an active site similar to that of methane mono-oxygenase hydrolase.	5.20273e-10
NC_021658.1|WP_148313612.1|4490003_4490636_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-ligand-binding-domain-containing-protein	gnl|CDD|379883	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal. This family of bacterial transcriptional repressors is characterized by the short approximately 50 amino acid stretch of residues constituting the helix-turn-helix DNA binding motif, around the YRFhY motif. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. Another target protein is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	1.45623e-16
NC_021658.1|WP_020735155.1|4490632_4491805_-|cobalamin-independent-methionine-synthase-II-family-protein	gnl|CDD|239427	cd03311, CIMS_C_terminal_like, CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme catalyses the last step in the production of methionine by transferring a methyl group from 5-methyltetrahydrofolate to L-homocysteine without using an intermediate methyl carrier. The active enzyme has a dual (beta-alpha)8-barrel structure, and this model covers the C-terminal barrel, and a few single-barrel sequences most similar to the C-terminal barrel. It is assumed that the homologous N-terminal barrel has evolved from the C-terminus via gene duplication and has subsequently lost binding sites, and it seems as if the two barrels forming the active enzyme may sometimes reside on different polypeptides. The C-terminal domain incorporates the Zinc ion, which binds and activates homocysteine. Sidechains from both barrels contribute to the binding of the folate substrate.	1.14346e-64
NC_021658.1|WP_020735162.1|4501038_4502283_-|right-handed-parallel-beta-helix-repeat-containing-protein	gnl|CDD|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	3.94019e-05
NC_021658.1|WP_020735150.1|4483237_4483867_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.41885e-07
NC_021658.1|WP_020735169.1|4508409_4510095_-|family-43-glycosylhydrolase	gnl|CDD|350130	cd18618, GH43_Xsa43E-like, Glycosyl hydrolase family 43, including Butyrivibrio proteoclasticus arabinofuranosidase Xsa43E. This glycosyl hydrolase family 43 (GH43) subgroup belongs to the GH43_AXH-like subgroup which includes enzymes that have been characterized with beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55), alpha-1,2-L-arabinofuranosidase 43A (arabinan-specific; EC 3.2.1.-), endo-alpha-L-arabinanase as well as arabinoxylan arabinofuranohydrolase (AXH) activities. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. AXHs specifically hydrolyze the glycosidic bond between arabinofuranosyl substituents and xylopyranosyl backbone residues of arabinoxylan. This subgroup includes Cellvibrio japonicus arabinan-specific alpha-1,2-arabinofuranosidase, CjAbf43A, which confers its specificity by a surface cleft that is complementary to the helical backbone of the polysaccharide, and Butyrivibrio proteoclasticus GH43 enzyme Xsa43E, also an arabinofuranosidase, which has been shown to cleave arabinose side chains from short segments of xylan. Several of these enzymes also contain carbohydrate binding modules (CBMs) that bind cellulose or xylan. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	3.46233e-172
NC_021658.1|WP_020735156.1|4492245_4493703_+|right-handed-parallel-beta-helix-repeat-containing-protein	gnl|CDD|275079	TIGR04247, nitrous_oxide_maturation_protein_NosD, nitrous oxide reductase family maturation protein NosD. Members of this family include NosD, a repetitive periplasmic protein required for the maturation of the copper-containing enzyme nitrous-oxide reductase. NosD appears to be part of a complex with NosF (an ABC transporter family ATP-binding protein) and NosY (a six-helix transmembrane protein in the ABC-2 permease family). However, NosDFY-like complexes appear to occur also in species whose copper requiring enzymes are something other than nitrous-oxide reductase.	7.87311e-16
NC_021658.1|WP_148314803.1|4512798_4514058_+|extracellular-solute-binding-protein	gnl|CDD|270242	cd13524, PBP2_Thiaminase_I, Thiaminase-I has high structural homology to the type 2 periplasmic binding proteins of active transport systems. Thiaminase-I, a thiamin-(vitamin B1) degrading enzyme, is a monomer in its biologically active form, with two distinct globular domains (N- and C-domains) separated by a deep groove. It has a structural topology similar to the periplasmic substrate-domains of ABC-type transport systems, such as thiamin-binding protein (TbpA), that possess the type 2 periplasmic binding protein fold. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.	3.32163e-79
NC_021658.1|WP_020735165.1|4504326_4505697_+|tyrosinase-family-protein	gnl|CDD|365987	pfam00264, Tyrosinase, Common central domain of tyrosinase. This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.	2.34604e-33
NC_021658.1|WP_020735153.1|4488902_4489928_-|hypothetical-protein	gnl|CDD|381626	cd19608, GH113_mannanase-like, Glycoside hydrolase family 113 beta-1,4-mannanase and similar proteins. Mannan endo-1,4-beta mannosidase (E.C 3.2.1.78) randomly cleaves (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans and is also called beta-1,4-mannanase, endo-1,4-beta-mannanase, endo-beta-1,4-mannase, beta-mannanase B, beta-1, 4-mannan 4-mannanohydrolase, endo-beta-mannanase, beta-D-mannanase, 1,4-beta-D-mannan mannanohydrolase, and 4-beta-D-mannan mannanohydrolase. (1->4)-beta-linked mannans are polysaccharides with a linear polymer backbone of (1->4)-beta-linked mannose units (in plants and fungi) or alternating mannose and glucose/galactose units (glucomannan in plants and fungi, and galactomannan and galactoglucomannan in plants), such as in the hemicellulose fraction of hard- and softwoods. Complete degradation of mannan requires a series of enzymes, including beta-1,4-mannanase. According to the CAZy database beta-1,4-mannanases are grouped into various glycoside hydrolase (GH) families; GH family 113 beta-1,4-mannanases include mostly bacterial and archaeal sequences.	1.48053e-11
NC_021658.1|WP_187345958.1|4498618_4500781_+|FAD-dependent-oxidoreductase	gnl|CDD|366721	pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase. This family consists of various amine oxidases, including maze polyamine oxidase (PAO) and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.	1.79311e-21

Protein sequences

>NC_021658.1|WP_044988277.1|4495256_4496123_+|NAD(P)H-binding-protein
MKILVTGATGTVGREIVKQLAEGGHHVGALSRNPGRAKFPDGVEAVAGDLAAPETFAAAFEGVEALHLINFGGDDCAKLQTGEQLVALARQAGVRRITMLLGGSSTPLDAAVAAGGIGWTFLQPVEFMANHLEWAASIRDEGIVREPFCDRRSAVVHEADIAAVAVAALTQDGHAGKKYTLTGPEVLSVREKIGLIAAAAGREIQLVELTEQQARERWAAAGFSPEAIEFFVEIHGSTPKIGYTVVPTVARVTGRPARTFARWAREHAAAFAGSPGRRSRRGARVSVT
>NC_021658.1|WP_187345957.1|4494493_4494652_+|hypothetical-protein
MKLVAMVTEPRNIARFLSALGEPTDVPARSPNRGPPYWKSTVLRRKALGDAA
>NC_021658.1|WP_020735156.1|4492245_4493703_+|right-handed-parallel-beta-helix-repeat-containing-protein
MNRSERIHAPHAAHRLAPSGILLLAVGLSPACAAPSGPDDAGADALEAGLAAAAGPCGDRSSGKIITVAPSGGDHRTIQAGLDAAAAGDTVLVKAGTYRENVSFGRSGTAAAGCITLQGETGAILDGTGRDGAGIEIASKSYIRVAGMTVQHFKGADTPIGISASGSSSFLEIRDNVVHHIESSEDAHGIAVYGTSATPMTDILIDGNEIRDCKLGSSESLVLNGNVTNFVVSRNEVHDNDNIGIDFIGFEGVGPSGSDQARNGVCVDNVVYNITSAQNPAYDGERSADGIYVDGGRNIVIERNKVDNSDIGIEVASEHRGRTTSNITVRNNFVSRSYQGNIMVGGYSTSVGSAASIAVLNNTLVQATGGEIILQNNSDGVLIQNNILYAKARNAYVSSGRNNRNVRVDNNIFFGASQTSAGAFTDPRARFVDPLLAGPPSDLHLTSGSPAVDAGVDLGGQGGASDIDGEARTRGARVDIGADER
>NC_021658.1|WP_020735155.1|4490632_4491805_-|cobalamin-independent-methionine-synthase-II-family-protein
MIKATKHKPLATTITGSLPRPSWYVAGLAGRRFSTAMADLVFREQYTDTLAVHITDQVRAGLDILTDGDARFDMDVGGRSWFGYLAERMEGMADPGLRPQPWTSPREREAGDILHEVMEARLPFFVRGPVGRGGLEYARVWKAAQRMTSRPMKLGTCCGQLLEAVLLNQHYADRRELLFALADSLNQELHEVADAGCPIVQLEEPMLHYVAGQDKGAELTAELYVDAFNREVAGLRDKTEVWVHTCWGNPAAQRVEVATSGYEGALGLLDRLDVDVITFEAASDGGAALPAIGGAIGKDKKVCIGVVHHRSLEVETPEQVAALVRKALRFIEPERLILSSDCGFGRQGMSRMHAFHKMVSLVRGANIVRRELGLEPSPCLAAEQRYSMLA
>NC_021658.1|WP_148313612.1|4490003_4490636_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-ligand-binding-domain-containing-protein
MTYRRSGDSVAAERRRGAVLELAILRAAAEELAEVGFPGLTMDGVARRAGTNKNAIYRRWPSRAALAVAAYRQLAADSAELPDTGSLRADVLELLRGANRHWSSPLGDVLRGLLAGVGGEPELLRELQEASNDGGSALWLTVLGRAVARGEAPPEALHPRVATAAVVLLRNEFITRGAPNVPESVLVEIVDEVYLPLIRGRGAPGPTQAR
>NC_021658.1|WP_020735153.1|4488902_4489928_-|hypothetical-protein
MRAYGICYDTGFLNKGNSTHEPFDPDRVRRDMRVIRGDLRCTAVRITGGDLDRLKIAATHAAAAGLETWICPFTTDLTGDELLALLAECADHGERLRRAGAEVVIVTGSELSLMNKGFVPGETFLDRSKVFTGRGPELRELLAAIPARLNALLARAVAVVRARFGGKVTYASLSFEGVDWTPFDIVSTDAAYRYAQNADRFPELIRAFVAQGKALGKPVAITEFGCATYAGAAAAGPRGADILVWDEATATPLGLNGAYARDEAEQANYLREVLEVLDAERVDAAFVHAFAGYILPHDPGEPRKDLDLASTGVVKVLKDGTWAPKEAFSMLAGYYDGRRRQ
>NC_021658.1|WP_020735152.1|4486574_4488806_+|excinuclease-ABC-subunit-UvrA
MDRQFIQVRGARENNLRDVSLDIPKQKITVFTGVSGSGKSSLVFDTIAAEAQRQLNETFTAFVQGFLPHYGQPDVDRIEHLNAPIIIDQKRVGGGSRSTAGTYTDIAALLRLLFSRVGQPAAGPAFAFSFNNPQGMCPECEGIGKTVQLDLDRFLDRSKSLNGGAILHPDFKVGKWMWKMYPLSGLFDSDKPIKDYSEEELRALLYGADVKVSFGEFGSKYEGLVERFTRMYLKKDAAAMSDRNRAVFEQFTTSQTCPACRGARLNQAALNCRINGRNIAEASDLEATELIAFLQGLTDPVAVRLAARLIERLQHLVDIGLGYLSLGRETATLSGGESQRVKMIRHLGNSLTEMLYILDEPSVGLHARDVARLNRLLQKLRDKGNTVLVVEHDPDVVAIADHVVDMGPKAGVHGGQVVFQGSYEALKGADTLTGRSLKQHLPIKRKVRQPTGQMLIKNAALHNLKNVTVGIPTGVLTVVTGVAGSGKSTLINDVFLEQHPEAIVIDQSRVTANSRSAPCTYTGIMDDIRQAFAKANKVSASLFSFNSEGSCPNCNGLGVVYTDLAFMEGIVSTCEICEGKRFKAEVLAYSLRGKTISDVLDMTVEEALAFFGEKKIKAVVQAMNDVGLGYLKLGQPLSTMSGGEGQRLKLATEIHKQGSVYVMDEPTTGLHLSDIGLLMGIIDRLVDARNTVVLIEHHLDVIRQADWIIDLGPEGGSAGGEVLFAGPPYELKGCERSITAKFI
>NC_021658.1|WP_148313611.1|4485111_4486074_-|hypothetical-protein
MAAVALAPRVVDERAGEEVEPLVLLDLDVSPDEPRAPNEPPMEPPRGLSPTSGADPGSARAASRGRAPAPPEAPSAQAPSAGPETHETAPPDEYGAPPPAAAPPGLDGSPVWALPGVLPAAPPAGSPAPTRPVPPRSAKNDAEEGGRGPMLVFPAAGTLASAVADEVSSSPAPEVSESSFELTLNAKGQLISARFLRANAGSGEDWRRIAQAVLRRFSGRALPMNGDFAAGSRVTVHVNSRVVVPDGTGHGIPMPMAKHDGGKPIIREDSLDDRFRSPHLAPSPGEAKFVLSFLTDLANLGAQRRRVVSTRVDAVPVALP
>NC_021658.1|WP_020735151.1|4484010_4484994_+|hypothetical-protein
MIGGSGHVGARAARALRRLHPDLRIAIGGRDGRKAAAVAAEVGGPTTAVTVDVQRSDLGLEPAASFSAIVTLVKDESSNALKRAQADGVPYIAFSDFVSEIGPLVAHYVARPTRAPILMLGHTFGGTATLAALHLAQELRSVDAIAIAAVVGADDHGGPASSADFERLRHVGEAALVLDDGKWTWLRGEAATRRVVDAEGAAHVGQALPLSDVVSLAAATDARSIRTDMAARDRAAGGAGPRTELIVEVSGRRRDGSGARLRYDIIDADNLSRLSAYGAAIATERLLGLAGGPPVGPGLYNPESVLDPASVIARLEELGARVRRTLA
>NC_021658.1|WP_020735150.1|4483237_4483867_-|TetR/AcrR-family-transcriptional-regulator
MAKTNAARTPTRPRGEAPGKRLPKAERREQLLETAEQIAREEGTEALTLGHLAERAGVSKPIAYEHFETRSGLLIALARQIDDRQVAALIEALKRTQKRLEDVARVVSAAYMHCCATVGPQWFAILAALKGDEQMDAVERELLDRYVTIYRDALAPCVQLSKRELHLRCVAIIGAAEALAAEMFRGRADEAAAAKALESLIVRWLSKVG
>NC_021658.1|WP_020735159.1|4496649_4497354_+|iron-containing-redox-enzyme-family-protein
MELATNIEPRPGAVVSEVEQRLGHLMMRHHPFFQRADAKDPRFLRTMLQLGFEFSEVLGRYLTLLAHRLWDTNKPVVSILVSQVHDELGRGKFTDDGHPNLYRDMVKGLEAWADGAAMEFMREPQKRLIQELKQCLGSDDVDQSLGAYVGTEIIASDITVHISQVMGRLGLSEEAMRWSQCHAVVELEHVQGIYEVPHHLPQDPERLRQFWGAAEEMMRAMWRYFDALNRFSFA
>NC_021658.1|WP_020735160.1|4497754_4498594_+|UbiA-family-prenyltransferase
MLVSPAPVDAGAAAVALLTLLASSAFMTHVNVLTDAELDASAKPELYRWLSVSRTFTVRAMAAELLASAAGIGWLLARGRALAGLGLGAFLALTVLYSYNYLSPGAAAARRLKAYWWGHLLTCLVSYFALWGAGLGLHTSGDARALAAWGPAFLFVSLSEYAVFLSESAVDAAEERRAGLKTLAALLGRRGSSLAAALLWLAAAAGLSLAGALASPEQRRLLLVCFAPAVLWRGSVVALLAAPLDQHRDRVLRLAVPDVTFFGSRLLTVVSLVVLDAAS
>NC_021658.1|WP_187345958.1|4498618_4500781_+|FAD-dependent-oxidoreductase
MTLFEHENTGPYDVAIIGAGLAGLAAAHALRDRNIIVLEKEPRPGGRVYTKSAGESFYDLGAVFAYDPAAAPIALRTPALHPESERIGLFAQGKVHYGISVRECLRQLDLAPHELDTLDAFETDPEKDASTLLPGAYRHLNSFFRLIHPGDMREYLPQRQHDAFIKFPTRHYETANGSLVEGLARPLEDRLETGVEVLSLTEKGGSVEVVFRRGEETHTLAARAVVCTAPAPVARRLVTTLTNDRCRVFLDSLRYGEGTVVVLGLEGADLADFSYIVTPDLPFNTVIKHRGRDGKPDTLFVYYVGEASEALSGLPHEEIVRRTLEHARALKVGALSEKTLRFADVHRWPMVGPRISPASYAKWTDWEARACERIFLAGDYVFVEPDNVLPFGTTQALQSGKRAAESVRAYLDVPAEVEALRSQTLIETTIYRLAGERPAFVQTKSECNISYYGLLLQANPSRPLTEYLLQSARESLWEYQVGFGVTADDSLLVLEGLVAAGVGRDVLQPKLDRLVELFYSRSQGAFHSLSERRAEIKGCAQGLADYWLGPSVYVSAHAGHLLHRVAPERYAQEVGACTQYVAGLQEPEGYWSSIWFSSKFVTTLHAAKLLGIHGERYRPQLWRATAFILATQGHDGSWGETVLETSAAVLALEALGEAGTAALRKAKSWLRARKKHDGWEGEPMLYYWFETGPAEKMFFHCRDKGAVTSAWATLALANPA
>NC_021658.1|WP_020735162.1|4501038_4502283_-|right-handed-parallel-beta-helix-repeat-containing-protein
MTIAISTPIQVDAETVVDGEGKITLDGGGTSRIFIVTNKLSVRNLSFINGKAPDDSNGGAVKGEWRSNVEVIGCTFEDNTAGTAGGAIGVWTGSSLTVVASQFRRNKSGYGGAIYSLWSPLHIVNSEFTDNSAFVDSNGGAIGTDGALDPAYRNPHDGVDTAGGTVEICGSRFQNNEAYGAGGAAFLWVYPPDKVIIDRCTVEGNTLGKDSGGTGVALGGGMRVSNGEITIKGTSFLSNIGETHGGGLYLDCDPTCTITDSTFYSNKATDGYGGAIFGDKLRVNNVTFAKNFAKGHGGALFGGSDWVFKNTVFADNKAGNPWGQAYSCSATGTGDHVLQWVTDFKGVGSDPCISNPTAADPKLADPADNGGITFTMLPGAGSPVLGAGAGCEPVDQRGQPRDTTACDLGAVEVP
>NC_021658.1|WP_020735163.1|4502983_4503412_+|hypothetical-protein
MGELAVALPQPAVDLLVFADGSLWLAGPETVARTGSLPEPLTGVRLRPGTCASVLGIGADEVSLDGMPLPGFDDPFQAPRQPARSPDRAIPRVIQAMHAAPGAPVAQHAAAVGLSERQLRRRFLVAGRRTPSEPRAGRSGPL
>NC_021658.1|WP_020735165.1|4504326_4505697_+|tyrosinase-family-protein
MPFQGDIGSSTRVRKSAFELTSSEVDKLRQAFAALRKLSVNDPADPRGWLQQANVHCWNCGGGEASVENIHGNYWFLPWHRAYLYFFEKILGKLVGDPDLALPYWDWDTRGRNVMPPPYVIPGNESNPLFDRYRGVAPWQAMPAWATSAEEMKRLLSLRDWASLMGGPAGSRRPGALEFGTHNRVHQWITDPRGRANCGVQDMGIFSTAGQDPIFFAHHANVDRLWEVWRNLGGEQRLPADAEFRQRTWTFYDENKRWVSISMDQILDNAGSLRYEYSRPSLVGRMGHGVAVSHPLTGAVTPAPSKSVAKAPGAAQLLTSEPQTVSAPVLVSAEIALFGAAPPSLEPTVRRLHVDGVALPPGGSTTVRVFVNLPDADERTPPSGPNYIGAFTVIPHHGSGHADVTRQDVAFELSAETEQVVPGAGAILVRLIPLAGEDMRPLGLTLEYQKVYVATE
>NC_021658.1|WP_148313616.1|4506034_4506517_+|hypothetical-protein
MHANHLCFENQVRLSGLIKEVGGHCEPRLLAGKRCPIDYTPRHMHFAPAGMSIWGYSPDLRYLKHITLVFNVRALEERVGERFSTEAASTPLQAVHSRTSIASVRRKSSARFVDRSIAATLAFRSGVIVRLRRLFWLRRARSDALAHGLAEASTPAYLTV
>NC_021658.1|WP_020735169.1|4508409_4510095_-|family-43-glycosylhydrolase
MATVTTSLQHKHLIAALLLCSTTVFPSESMADNPIVQTIYTADPAPLVHDGTLYLYTGHDEDSASTFFGMNEWRVYSTTDMVNWTDRGSPLKYKDFSWSKADAWAGQVAHRNGKFYFYVPTTSRTHNRMVIGVAVSDSPVGPFEDALGGPLINANCGDIDPTVFIDDDGQAYLYWGNPNLCYVKLNEDMISYQGEVVRVPMTAESFGERTGSAERPTLYEEGPWLYKRNGMYYLAYPAGGIPEYIAYSTSSSPTGPWTYRGVIMPTEGGSFTNHPGIIDFKDNSYFFYHNGALPGGGGYHRSVAVERFTYNEDGTIPTITMTEAGPPGVDTLNPYVMTEAETIAWEAGVETEACSEGGMNVTSIEDGDYIKVKDVDFGSGAGSFDARVASATSGGSIELRLDSPTGTLVGTCVVQGTGGPQTWVTESCPVDVVKGIHDLYLKFTGGNGPLFNFNWWKFTPLDATDPTGGGGGPDTGEGGATGTGGSGEGGSVSSAATTGSGTGGAGAAPPDGAGEDEGGCGCRVMSGPISPAGALAALTALGAIVARRRARKDGRSAAAAN
>NC_021658.1|WP_020735170.1|4510565_4512347_-|hypothetical-protein
MVEIDFYKLPRAIQDGVLEAFRGRFAPAPIVSRPGTRPTIVAWLAVSAAAGLLLAALCAAGFGDVDSAVALHPTAAAAAYVLLAATTAIGVLRALAYNADLVSLPFAPGLFVFPANLVDARDHRLRVFSLAELSRVSAGPRGAVVLTFGGTRHAFPLEDPSRSDDVIREIEAAWSRMRANPDPAELRRLDPFQPPAIESPFASPIPLSRVVPGWQSYAWLLAAAVGVALGLALFSLRNRMSDARMYAAARARDDVAAYQRYITRGRGHGGVVSQVLLPRAELRLAVAKGSVEAIDDFIRAYPKTGIQAEVAAARRAALAAALERAREVGTLAALVAFAERYPKHGLDKAFNDERHALYVRALDRYKREMPEGSEQNADFVRRLLAYAERVGPKSTPQGLRGPAVQVRFRRLPSQDLERADELVMKSPMFSGVTSLPTRYVDATRLDPQEKRTATALAEGLARGFAPELVTFEPGPPFEGSAEEQVSVTSPALVVSYRVESSGMAYGSKKPQIIVMGLKFLFKTEFILPGDAEPLLTSHKIARQIPAGLIQQQVGSPPRGTLEAIVYEAMMREAFIDLGERYLSTWFRKRDEPR
>NC_021658.1|WP_148314803.1|4512798_4514058_+|extracellular-solute-binding-protein
MDDGSSAGAGGSGGQGGSGGEDGSGGQGGSAGEKTVLRVPLYPYIPDAAGDKLAAMALRIEAEFEEAHAGIDLVVNPPCFAADVYDPAALAMGLAGEDADCSVDVIETDMILLGELVATGAIRPWSELPPADWHPAGIEASTYDGEIYGVPHWLCGHFTFSRDASVESAGTAAELASALVDLQTDAPDMAGNLLGSWNLPSLYLDAWADTNGPEGVASAISTTMYDAATLDALGIFARTCESEGSNPCLDGTYDREENVDLPAQRFAAGEVDATFGYSERLHTILKNLPPGGDPAEIKLASAPLGDGNRPLLFTDSFVVSARCTDACADAAAAFVAYMSSASTFAWILASEDAPQEARVPRYLMAATFDAYSAPTIGADPFYQAINALTEEGKSFPNGGLLDVRSEMRDDLLATLTSAP

Crispr_ID: NC_021658_13

• CRISPR_ID: NC_021658_13
• CRISPR_location: 4522725-4522810
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_13

Consensus_repeat	Method
CCGGGAGATCGCCGGGCGATCCCC	CRISPRCasFinder

spacers of NC_021658_13

>13.1|4522749|38|NC_021658|CRISPRCasFinder
CCGATCGCAGGAGCGCTCCCGGATCGCCCCCTCGCGGT

CRISPR arrays and Neighbor proteins around NC_021658_13

CRISPR arrays

The CRISPR arrays of NC_021658_13

>merge|NC_021658|13|4522725-4522810|CRISPRCasFinder
CCGGGAGATCGCCGGGCGATCCCCCCGATCGCAGGAGCGCTCCCGGATCGCCCCCTCGCGGTCCACGCGATCGCCGGGAGATCGCC

>NC_021658|13|10|4522725-4522810|CRISPRCasFinder
CCGGGAGATCGCCGGGCGATCCCC	CCGATCGCAGGAGCGCTCCCGGATCGCCCCCTCGCGGT
CCACGCGATCGCCGGGAGATCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_148313619.1|4539270_4540215_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735177.1|4522974_4525560_+|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl|CDD|224006
NC_021658.1|WP_020735186.1|4540317_4544217_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020735170.1|4510565_4512347_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735172.1|4515010_4515475_-|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NC_021658.1|WP_080682149.1|4515670_4516180_-|DUF1304-domain-containing-protein	unknown	unknown	gnl|CDD|377753
NC_021658.1|WP_020735165.1|4504326_4505697_+|tyrosinase-family-protein	unknown	unknown	gnl|CDD|365987
NC_021658.1|WP_049949527.1|4514184_4514724_+|hypothetical-protein	unknown	unknown	gnl|CDD|240291
NC_021658.1|WP_020735175.1|4516363_4520260_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_044988285.1|4532301_4536198_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_044988286.1|4536406_4537501_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020735169.1|4508409_4510095_-|family-43-glycosylhydrolase	unknown	unknown	gnl|CDD|350130
NC_021658.1|WP_187345959.1|4529529_4532283_+|carbohydate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|119337
NC_021658.1|WP_020735178.1|4525635_4527396_+|PTS-transporter-subunit-EIIC	unknown	unknown	gnl|CDD|273920
NC_021658.1|WP_020735179.1|4527395_4528493_+|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl|CDD|238434
NC_021658.1|WP_020735180.1|4528509_4529520_+|SIS-domain-containing-protein	unknown	unknown	gnl|CDD|225132
NC_021658.1|WP_080682729.1|4520968_4522603_-|chitinase	unknown	unknown	gnl|CDD|119365
NC_021658.1|WP_148314803.1|4512798_4514058_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270242
NC_021658.1|WP_080682152.1|4537908_4539087_+|hypothetical-protein	unknown	unknown	gnl|CDD|173848
NC_021658.1|WP_148313616.1|4506034_4506517_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020735177.1|4522974_4525560_+|phosphoenolpyruvate--protein-phosphotransferase	gnl|CDD|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NC_021658.1|WP_020735186.1|4540317_4544217_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.76856e-87
NC_021658.1|WP_080682152.1|4537908_4539087_+|hypothetical-protein	gnl|CDD|173848	cd01159, NcnH, Naphthocyclinone hydroxylase. Naphthocyclinone is an aromatic polyketide and an antibiotic, which is active against Gram-positive bacteria. Polyketides are secondary metabolites, which have important biological functions such as antitumor, immunosupressive or antibiotic activities. NcnH is a hydroxylase involved in the biosynthesis of naphthocyclinone and possibly other polyketides.	4.45707e-105
NC_021658.1|WP_020735172.1|4515010_4515475_-|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.000906962
NC_021658.1|WP_080682149.1|4515670_4516180_-|DUF1304-domain-containing-protein	gnl|CDD|377753	pfam06993, DUF1304, Protein of unknown function (DUF1304). This family consists of several hypothetical bacterial proteins of around 120 residues in length. The function of this family is unknown.	9.68428e-31
NC_021658.1|WP_020735165.1|4504326_4505697_+|tyrosinase-family-protein	gnl|CDD|365987	pfam00264, Tyrosinase, Common central domain of tyrosinase. This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.	2.34604e-33
NC_021658.1|WP_049949527.1|4514184_4514724_+|hypothetical-protein	gnl|CDD|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	3.01434e-06
NC_021658.1|WP_020735175.1|4516363_4520260_+|AAA-family-ATPase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.25773e-81
NC_021658.1|WP_044988285.1|4532301_4536198_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.81451e-88
NC_021658.1|WP_044988286.1|4536406_4537501_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.46676e-95
NC_021658.1|WP_020735169.1|4508409_4510095_-|family-43-glycosylhydrolase	gnl|CDD|350130	cd18618, GH43_Xsa43E-like, Glycosyl hydrolase family 43, including Butyrivibrio proteoclasticus arabinofuranosidase Xsa43E. This glycosyl hydrolase family 43 (GH43) subgroup belongs to the GH43_AXH-like subgroup which includes enzymes that have been characterized with beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55), alpha-1,2-L-arabinofuranosidase 43A (arabinan-specific; EC 3.2.1.-), endo-alpha-L-arabinanase as well as arabinoxylan arabinofuranohydrolase (AXH) activities. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. AXHs specifically hydrolyze the glycosidic bond between arabinofuranosyl substituents and xylopyranosyl backbone residues of arabinoxylan. This subgroup includes Cellvibrio japonicus arabinan-specific alpha-1,2-arabinofuranosidase, CjAbf43A, which confers its specificity by a surface cleft that is complementary to the helical backbone of the polysaccharide, and Butyrivibrio proteoclasticus GH43 enzyme Xsa43E, also an arabinofuranosidase, which has been shown to cleave arabinose side chains from short segments of xylan. Several of these enzymes also contain carbohydrate binding modules (CBMs) that bind cellulose or xylan. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	3.46233e-172
NC_021658.1|WP_187345959.1|4529529_4532283_+|carbohydate-binding-domain-containing-protein	gnl|CDD|119337	cd06569, GH20_Sm-chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NC_021658.1|WP_020735179.1|4527395_4528493_+|N-acetylglucosamine-6-phosphate-deacetylase	gnl|CDD|238434	cd00854, NagA, N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.	3.78636e-136
NC_021658.1|WP_020735180.1|4528509_4529520_+|SIS-domain-containing-protein	gnl|CDD|225132	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane].	2.12907e-94
NC_021658.1|WP_080682729.1|4520968_4522603_-|chitinase	gnl|CDD|119365	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.	7.04547e-140
NC_021658.1|WP_148314803.1|4512798_4514058_+|extracellular-solute-binding-protein	gnl|CDD|270242	cd13524, PBP2_Thiaminase_I, Thiaminase-I has high structural homology to the type 2 periplasmic binding proteins of active transport systems. Thiaminase-I, a thiamin-(vitamin B1) degrading enzyme, is a monomer in its biologically active form, with two distinct globular domains (N- and C-domains) separated by a deep groove. It has a structural topology similar to the periplasmic substrate-domains of ABC-type transport systems, such as thiamin-binding protein (TbpA), that possess the type 2 periplasmic binding protein fold. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.	3.32163e-79
NC_021658.1|WP_020735178.1|4525635_4527396_+|PTS-transporter-subunit-EIIC	gnl|CDD|273920	TIGR01998, N-acetylglucosamine_and_glucose_PTS, PTS system, N-acetylglucosamine-specific IIBC component. This model represents the combined B and C domains of the PTS transport system enzyme II specific for N-acetylglucosamine transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, N-acetylglucosamine-specific IIABC component". This family is most closely related to the glucose-specific PTS enzymes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	4.85287e-175

Protein sequences

>NC_021658.1|WP_080682729.1|4520968_4522603_-|chitinase
MPIAGWTSNDRQPANPRRSVMKLDALTTLPLFAVIALAACGGIDGDDAERFGPDGAELESTEQAAVAAAWAPYTAYAVNAEVTYGGVTYRCIQAHTSLPGWEPPIVPALWQPVSGAGTTTTSSSTTSSSSGGAGGSGGSGGSGGSGGSGGSGGAGGGGSGGGGGGKKVIGYFAEWGVYGRNYHVKNIDTSGSAEKLTHINYAFGNVVGNRCALGDTYADYDKAYSAADSVDGVADTWDAGALRGSFNQLRKLKRKHPHLKVLISLGGWTWSAGFSDAALPANRASFVSSCVDLFIKDPRWAGVFDGIDIDWEYPAACGSTCNQRPEDTQNFTALLSEFRSQLNAVRPGLLLTIAAPAGLDKIEKIQVGQIHRHLDFINLMTYDMHGAWERTTNFHSPLYNSGANPAKALKYSTDEAVAAWLNGGTPASKLVVGVPFYGRGWTGVASANQGVWQSAAGAAPGTYEAGIEDYKVLKAKGHPGFTHPDTKAFYTFNGTEFWSYDNPASLGVKMRYIKDKGLGGAMFWELSGDTANGELVAAVRNGLR
>NC_021658.1|WP_020735175.1|4516363_4520260_+|AAA-family-ATPase
MRAPDVVDGRFEIERLAGSGGMGDVYRARDRLSGQAVALKVLQSATVRDLSRLSREAEALVTLRLPGVVQYVGHGVTDAGRPYLAMQWLDGITLEERLARGPLSIPESVALAARMATTLGAIHQLGIVHRDLKPSNLMLVGGAIERATLFDFGIASGLRLAQGLTSPGAILGTPGYMAPEQARGESAVDARADVFALGCMLFECLAGRPPFLGDSALSLIMKVVLEDPPRLGELRDGIPEPLDRLIARMLSKPAAERPRDGAAVAEELASLVVEGVPAGGSETTEPPASGEGITTAERRVMCVILAADCSAEAAVTLVEADLTLAEADRGARAEALRELAARHGGRLELLQAQWLLITLSGAEAPTDLAARAAHCALALRAELGGVPMAIATGRAEIAGRLPVGALIDRVVQLFAQRAGALGPHTRLDDATAGLLASRFETAQGPDGCWLRGPKEEPDTVPRLLGKPTPCVGRERELSQLATEWRHCVEETTASVVVVVGAPGLGKSRLAWEFLRALRGDGGAAEIWIGRADPVAAGSAFGLLARALRRAMGILDGERLEAQRSKVLARVEQLDGLGDKGLHVAAFLGELVGATFPDDGDVQLQAARQNPALMGDRLREAFEDFVRAECQRRPVVLVLEDLHWGDLPTVTLVDAALQHARDQPFFVLALARPEVHELFPALWSERNGLRIRLAPLPRRASERLVREVLGDDVRAEQVEGLLARSDGNAFVLEEQIRAVAEGRSDGLPESALAMVQARLEALDIEERRVLRAASVFGETFWENGVSALVGGAPVARRLTELARRELILRRHEARIAGEVEYEFRHALVREAAYGMLTERDRRVGHGLAGDWLARAGGADPMALAEHFEQGGQEKRAADAYRRAAEEALRGGDLAAAIERAKRGIACGPTAQALGALRLVEAEAHVWRGELALAEQRGAEAVERLPAGTAPWFSAIKQAALAAGKLGGFERVARWMTTAQAAEAADGALVAKHMCLGNGALLLVFGGRYALADALIWAIEGDGTDLAEREVEVAAWLHQARAIRAHVHGDPGACLVGLEAALAALERIGDRRNACTVRMNVGYIHAELGDFAGAEEVLRSALAGAERMGLHELAATTLSNLGHVLGYRGRIEDAQRTEREAIARLHRLGDPRAEGSARTYLARIALLARDFEAAEREARTAAEILQSAPPLRAAAVAARARALLGLRRFDEGLSAAGEANSMLESFGTLEEGESLVRLTFAESLAANGRHDAAAAAIASARAALLARAERLSDPPWRERFLRDVPDNARTLELARQWLGS
>NC_021658.1|WP_080682149.1|4515670_4516180_-|DUF1304-domain-containing-protein
MPTAARIVVTRIGIHHIYILVMEMFSWRSERTCSAFCTMPGVAAITAPLAANQGLYNRFLAAGLRWGVIRPNKDFAWQIRSLFVLCVAVTGAHGAATVKRSILSVQTVPSHIGLALVRARTAAGRARPPARRGGPRSRRCRRRAARSGQRAPRPAAAAARPRAARSPPA
>NC_021658.1|WP_020735172.1|4515010_4515475_-|hypothetical-protein
MRATLSPASRAASCLATSEPRSRAERTSTPAGSSVSCGCSATPNVRASSAHTSAGSSGSNRSPKRSASSQSICTCRSSRSTVSPPSASAAAGIATSPPSPFVSAVAAAAPVESAPVAPPASAERTQARRMTARACVRSVTPVDAAMLAGRGRRL
>NC_021658.1|WP_049949527.1|4514184_4514724_+|hypothetical-protein
MAGAKRADAFLAMALSGLAAAAAVGCTALAGLDDAYHLVGGSGGGGAAGGAGGAGGSGTGGQAGGSTGGSGTGGEAGGGAGGDVGGWGGGGAGCATCALPPYDAADPAELCEWSAAIYGALMECLCAECGAVEGSPCYGGCGAGEGRSAECNDCLASAAAEIEGACAPEVAECEFDTGE
>NC_021658.1|WP_148314803.1|4512798_4514058_+|extracellular-solute-binding-protein
MDDGSSAGAGGSGGQGGSGGEDGSGGQGGSAGEKTVLRVPLYPYIPDAAGDKLAAMALRIEAEFEEAHAGIDLVVNPPCFAADVYDPAALAMGLAGEDADCSVDVIETDMILLGELVATGAIRPWSELPPADWHPAGIEASTYDGEIYGVPHWLCGHFTFSRDASVESAGTAAELASALVDLQTDAPDMAGNLLGSWNLPSLYLDAWADTNGPEGVASAISTTMYDAATLDALGIFARTCESEGSNPCLDGTYDREENVDLPAQRFAAGEVDATFGYSERLHTILKNLPPGGDPAEIKLASAPLGDGNRPLLFTDSFVVSARCTDACADAAAAFVAYMSSASTFAWILASEDAPQEARVPRYLMAATFDAYSAPTIGADPFYQAINALTEEGKSFPNGGLLDVRSEMRDDLLATLTSAP
>NC_021658.1|WP_020735170.1|4510565_4512347_-|hypothetical-protein
MVEIDFYKLPRAIQDGVLEAFRGRFAPAPIVSRPGTRPTIVAWLAVSAAAGLLLAALCAAGFGDVDSAVALHPTAAAAAYVLLAATTAIGVLRALAYNADLVSLPFAPGLFVFPANLVDARDHRLRVFSLAELSRVSAGPRGAVVLTFGGTRHAFPLEDPSRSDDVIREIEAAWSRMRANPDPAELRRLDPFQPPAIESPFASPIPLSRVVPGWQSYAWLLAAAVGVALGLALFSLRNRMSDARMYAAARARDDVAAYQRYITRGRGHGGVVSQVLLPRAELRLAVAKGSVEAIDDFIRAYPKTGIQAEVAAARRAALAAALERAREVGTLAALVAFAERYPKHGLDKAFNDERHALYVRALDRYKREMPEGSEQNADFVRRLLAYAERVGPKSTPQGLRGPAVQVRFRRLPSQDLERADELVMKSPMFSGVTSLPTRYVDATRLDPQEKRTATALAEGLARGFAPELVTFEPGPPFEGSAEEQVSVTSPALVVSYRVESSGMAYGSKKPQIIVMGLKFLFKTEFILPGDAEPLLTSHKIARQIPAGLIQQQVGSPPRGTLEAIVYEAMMREAFIDLGERYLSTWFRKRDEPR
>NC_021658.1|WP_020735169.1|4508409_4510095_-|family-43-glycosylhydrolase
MATVTTSLQHKHLIAALLLCSTTVFPSESMADNPIVQTIYTADPAPLVHDGTLYLYTGHDEDSASTFFGMNEWRVYSTTDMVNWTDRGSPLKYKDFSWSKADAWAGQVAHRNGKFYFYVPTTSRTHNRMVIGVAVSDSPVGPFEDALGGPLINANCGDIDPTVFIDDDGQAYLYWGNPNLCYVKLNEDMISYQGEVVRVPMTAESFGERTGSAERPTLYEEGPWLYKRNGMYYLAYPAGGIPEYIAYSTSSSPTGPWTYRGVIMPTEGGSFTNHPGIIDFKDNSYFFYHNGALPGGGGYHRSVAVERFTYNEDGTIPTITMTEAGPPGVDTLNPYVMTEAETIAWEAGVETEACSEGGMNVTSIEDGDYIKVKDVDFGSGAGSFDARVASATSGGSIELRLDSPTGTLVGTCVVQGTGGPQTWVTESCPVDVVKGIHDLYLKFTGGNGPLFNFNWWKFTPLDATDPTGGGGGPDTGEGGATGTGGSGEGGSVSSAATTGSGTGGAGAAPPDGAGEDEGGCGCRVMSGPISPAGALAALTALGAIVARRRARKDGRSAAAAN
>NC_021658.1|WP_148313616.1|4506034_4506517_+|hypothetical-protein
MHANHLCFENQVRLSGLIKEVGGHCEPRLLAGKRCPIDYTPRHMHFAPAGMSIWGYSPDLRYLKHITLVFNVRALEERVGERFSTEAASTPLQAVHSRTSIASVRRKSSARFVDRSIAATLAFRSGVIVRLRRLFWLRRARSDALAHGLAEASTPAYLTV
>NC_021658.1|WP_020735165.1|4504326_4505697_+|tyrosinase-family-protein
MPFQGDIGSSTRVRKSAFELTSSEVDKLRQAFAALRKLSVNDPADPRGWLQQANVHCWNCGGGEASVENIHGNYWFLPWHRAYLYFFEKILGKLVGDPDLALPYWDWDTRGRNVMPPPYVIPGNESNPLFDRYRGVAPWQAMPAWATSAEEMKRLLSLRDWASLMGGPAGSRRPGALEFGTHNRVHQWITDPRGRANCGVQDMGIFSTAGQDPIFFAHHANVDRLWEVWRNLGGEQRLPADAEFRQRTWTFYDENKRWVSISMDQILDNAGSLRYEYSRPSLVGRMGHGVAVSHPLTGAVTPAPSKSVAKAPGAAQLLTSEPQTVSAPVLVSAEIALFGAAPPSLEPTVRRLHVDGVALPPGGSTTVRVFVNLPDADERTPPSGPNYIGAFTVIPHHGSGHADVTRQDVAFELSAETEQVVPGAGAILVRLIPLAGEDMRPLGLTLEYQKVYVATE
>NC_021658.1|WP_020735177.1|4522974_4525560_+|phosphoenolpyruvate--protein-phosphotransferase
MHPSESLTLLAPLSGPIVPIESVPDAVFADKIVGDGISIDPISQTLLAPCDATVTQLHAARHAITLSAAGGVEIMIHVGIDTVGLKGEGFTARVSQGDRVSAGQALLEFDADLLLRKAPSLLTQIVVLSGETSAIVERASGVARAGVSRLMTVSPRRRAGGGAPRASSAGEAGASRPPPRATVGVTSAVVVVPNPHGLHARPAAVLASEAKSFAADISVELAGRNANAKSVVALMNLGAGPGAELRIVGSGSEAARAVARLVELVRSGLGEDLSAANAARTAEPERAAAAPSSSTPRAADDARHVHGVSASPGLAIGPICKIDPLAADVDEHASDTEAELARLQKALRHTRLELKQLVAASGKRVEQAQIFSAHLTMLDDPEMITRTEVAIVEGKSAAFAWREAVMASCRELARLSNPLLAARANDLRDVGGRALRHLVGGGEAQAAPAGSVVVAESLTPSEVVRLADQRVAGLVSVLGGTTSHAAILARSLGLPYLVGASASLLAVEAGATAVLDAEGAVVLLRPTEAELDAYRGRLGARKALRERQEAAAGERAVTRDGVRVAVLANIASADDARKAVRLGAEGVGLLRTELMFFDRDAAPTEAEQTAAYQEIADALGERPLVVRTLDVGGDKPLSYMPLPAEDNPLLGIRGLRIGALHPALLRSQLRAILAARAPAGHRILLPMVASLEELREAKQVLEEERRRAGSPPVELGVMVEVPSVAVQADRFAAEVDFFSIGTNDLTQYTLAMDRTHPRLAGRQDALHPAVLRLIDTAVQAAKKRERHVGICGAVASDPEAVAVLVGLGVTELSVSVQAIPEVKARIRELDAARCREIARAALDLGTAAEVRALLAPGARPG
>NC_021658.1|WP_020735178.1|4525635_4527396_+|PTS-transporter-subunit-EIIC
MRGFNELQRVGKALMLPIAVLPVAGLLLRLGQPDVLDIAFVAQAGGAIFDNLALIFAVGIAVGLAREANGVAGLSGMIAYLVITNGVKSIDDKIKMGVLAGILAGVLAGAMYNRFRDTKLPSFLGFFGGSRFVPIVTGGASLALALVLGVVWPTIQAGIDAVGGWIVASGPVGAFFFGLLNRLLIPTGLHHILNNLAWFVVGSFQGAKGAVTGDLNRYFAGDPSAGVFMAGFYPVMMFGLPAACLAIYRTARPENRKATFGVMFSAALTAFLTGITEPIEFAFMFLAPALYAVHAVLTGLSLALLDVLGVKHGFSFSAGFIDYALNYGLSTKGWMIVPIGLAYAVVYYGLFVVCIERFNLATPGREAAAAPSAVASEGGGVEASGGAEAGAGVEAGAGGLAGQLLRALGGHGNIREIDACITRLRLVMVDRDRVKDADLRALGAKGVVRPGTDSLQVILGPMAESIAKEMRELAGRAGAAAVEPKAADAARGGAPAAPAARPEARPEMWIERWLAALGGAANIRSVEGFSSGRVRVELADADPIDEAALEAADVKGVMRLSDRVVHLLVGPEAPRYAAALAQKLKG
>NC_021658.1|WP_020735179.1|4527395_4528493_+|N-acetylglucosamine-6-phosphate-deacetylase
MGVELVGNILTPDGWLRGRVYFGARVQEIAGAPASGPGQGPRIVPGFIDLHVHGGGGRDVMEGGDAPRAMARAHAATGTTSLLATTMTAPLPEIAAALRAIRAAMDARRRGEARVLGVHLEGPFLNPGRLGAQPPCVVGGDLDTALALSSIAPIRVLTLAPELAGHLELVRRLSGLGVRVQIGHTLSSYEEVVAALAAGASGFTHLFNAMNGLHHREPGAVGAALAHGDFAELIPDLVHVHPGAIRAALRCIPRLYAVTDGTAASGMPDGPYQLGAHAVAKCQNSVRLPDGTLAGSCLTMHQAFKNLVDLGLPLAEASRRCSQFPAEHLGLEDRGRIAPGCFADLLVLEEDLALRQVLVEGEPLE
>NC_021658.1|WP_020735180.1|4528509_4529520_+|SIS-domain-containing-protein
MAEEARSAPEIVAQQLAQDEDAYRELGARLRAAPPPSVVTIARGSSDHAAGYLAYLVMTRLGCPVASLPPSVVTLYRAPLRLPGGLAVAVSQSGQSPDVVGALSACGAAGAMTAALVNQLGSPLAQAAATTIPLRAGPERSVAATKSFIASLSAMARVVAIWGEDAALLDALQALPETLAAASESDVGPLVGALSGEERLLVLGRGPGFSIALEAALKFKETCGVHAEAFTVAEVQHGPMALIDERFPLLVFAPRGPAQAGLVRVAEEFRAQGAKVILVGPAGLPGVDLAVPASPHELLDPLCQILAFYLAAAALAEARGLDPDAPRRLKKVTKTL
>NC_021658.1|WP_187345959.1|4529529_4532283_+|carbohydate-binding-domain-containing-protein
MRRPVFRFGLLAGALFVAGCGDDGTSSSTASTTMSTSTGNGGGGGGGGTGGGGGTGGGGGSAQERPSGADFAVTWSVLDNHKNPAVSFGSELTIENRGKVALGNSGWTLYFNFVRLIVPESLPPGVKVTHINGDFFKLEPTEAFQPLEPGQSAVIPFDGSYWAIKETDAPAGYYFVFTDGEGVASAPEAVGSEAVAPFVEKKQTDRFPGDMTPVPTAASRYDENLAVRLLPAGDVDRVVPTPVLLEAGDGELSLSSAVPIYHAAGLEGEAAFLAEALGALLGAAPEVREGAPPAGTAAIALATGAIDVGGQPKQAGDEAYRLTVTPEGVEIVGSDAAGVFYGIQSLRALAPVEAYRTAKPEIAIGAVTVEDAPRFGYRGMHLDVARNFQRKEAVLKLLDVMAFYKLNKFHFHLTDDEGFRFEVSGLPELTEVGARRGHTLDDRDQIVPSFGSGPDPASPSSSGSGHYTRAELVEILRHAKARHIEVIPEIDMPGHARAAVKAMEARYARLAAEGDVEKAEEFLLSDLEDPSQYMSVQMWTDNVVNPCRESTYRFLRKVVDDVVAIYAEAGATLTTIHTGGDEVPDGVWEQSPSCEALLGQAPGGVESVDDLASHFLRELNAIVASHGLVTGGWEEIALKKVQAEGGVDKEANPEFVSSNFRAYVWNNVWGWGDEDNGYKLANAGYPVVLSNATNLYFDLAYDKDPAEPGYYWAGFVDTRKPYEFVPFDVYKSAHADRMGNPIDPAEMFRDHVKLTDAGRANVLGIQGQLWGENAKGQGAMEYLIFPKLIGLAERAWAPDPAWAAEEDGAARAGLLAEAWSRFANSLGQRELPRLDHLSGGVDYRLPLPGARVEDGKLVANVAFPGLQIRYTTDGAEPGADSAVYEGPVAVSGVVKLRTFDTRGRGSRTSVLDPDGSQ
>NC_021658.1|WP_044988285.1|4532301_4536198_-|protein-kinase
MRVGDVLEGRFTLDARAGSGGMGEVFRARDDATGQAVAVKVMLARHTAERARFEREVRVLSELSHPAIVQFVAHGETPDGEPYLAMEWLEGEDLRARLARGMLGVDESVALAARVAAALGTAHARGVVHRDLKPSNLFLPAGDVALVKVLDFGIAHLGDVTRLTRTGAILGTPGYMAPEQAGGAGALDARADVFALGCVLYECLTGTPAFAGERLMAVLAKICCEEPPRVAALRAGVPPALDALVARMLAKQPDRRPRDGASVAAELSALAGDPSGAHADPAGHSTLALAGERRVVSVVMLGRESPLWLDATEPLGPNSTLEPEEDELRDTAASFGGRLDVLADGSAAVTLSGDFVATDLAARAARCALTLHGIHPSRPMAVATGRSEGAGMRPLGDVIDRAARLVARRGPGAQPVVLDDLTAGLLDARFEVAAGEAGYELLREHDVVTGSRTLLGKRTACVGRARELAVMAGLLSECVDEPVARAVLVTAPAGVGKSRLCHEFLRAARARGAPIEVWIGRGDALRGGQAFGALGQALRGTCEIREDDPPEARRDKLRARVARRVTQADRARVTWFLGELAGAAFPDDESAPLRAARAKAELMSEQVRRAWEDFLLAECAAGPVLLALDDLHWADHATVRLVDAALRVAKDLPFLVLASARPEVHERFPRLWAERELQEIRLGALTPKASEQLVRQVLGDAVPAETVRRLVSRSRGHAFYLEELIRAVAEGRDTLPETVAAMVQAWIERFEPEARRLLRTASVFGEVFWPGAVASLLGGEPDAGDVGSGLAARIDQLVQQEALVRRPESRFAGEPELAFRHALLAEGAYAMLTDEDRTLGHRLAGAWLEERGESAPVVLAEHFERGGEPVRAADLYRRAADQAVRLGTMEAAIVYAHRGLACAPSDELRLALLDVLWEAYLWSREHAHPQVTRDAEQMMSLATPGSGLWMRGALLKLFALLAARQPEAFTATLHAVRAVEPLPDAAAAVADTLYMGVAYLLFQGQLRVAEPFLRWLEDIVEPVAESAPRARGFRDMARSFYAMYADEDPWSGVEWAEAALEGFERGGSLVDVAHARTLVAAGLWFLGARARGAQILRDTPPCTDEDVWLAVANRSMFLGEILIDQGAIEEGRLIAEGIIEAGRARRVAPYEGMGRRLLSYALFHRGDLEAAEREALTALGMPSTTPGERAVLKRTLAAVRLAQGRVAEALADAEEAMAGYEALRMFFAKGSLARLIHAEALMAVADQQRALAAIAEARARLLANAAKIGDPELRRSFLEDIRENARTLELARAWLGDA
>NC_021658.1|WP_044988286.1|4536406_4537501_-|protein-kinase
MRVGDVLEGRFTLDARAGSGGMGEVFRARDDATGQAVAVKVMLARHTAERARFEREVRVLSELSHPAIVQFVAHGETPDGEPYLAMEWLEGEDLRARLARGMLGVDESVALAARVAAALGTAHARGVVHRDLKPSNLFLPAGDVALVKVLDFGIAHLGDVTRLTRTGAILGTPGYMAPEQAGGAGALDARADVFALGCVLYECLTGTPAFAGERLMAVLAKICCEEPLRVAALRAGVPPALDALVARMLAKQPDRRPRDGASVAAELSALAGDPSGAHADPAGHSTLALAGERRVVSVVMLGRESPLWLDTTEVEAPPGTPAEHELRDTAALFGPRLDVLADGSAAVTLSGDFVATDLAARAAR
>NC_021658.1|WP_080682152.1|4537908_4539087_+|hypothetical-protein
MTRGAEMTHDDLVARAARLVPRLRERARETETLRRLPDETVGELRASGLLDLFKPRSHGGHQASLRTAFEVGTQLARGCGSTSWIVSQLNLALWMACALPEGVREEILRQPDSSILFALLGRGSAERVAGGYKINGVWPFCSGSHHITWIGLGLPVEDGRGGAAPAFFIVPASALEILDDWHVSGFCGTCSNSTAAHDLFVPDRRVAPVSTVFSGELLSPDLTGSPYRCPIVQGIVVTAASCALGMAQAAIEVFKAQTEGRGISFTLYEKKAEAPVTHLLLSEAAMKVRAADLLLHAAVEDLERRAAGAGATDVELLIRIRTEVAFAIHLCREAVETLFGASGGSALSLSNPIQRIARDARAICQHAAYCLPTNLEAHGRVMLGLSPNLSFV
>NC_021658.1|WP_148313619.1|4539270_4540215_+|hypothetical-protein
MMIGMYALAAGAGCEPGGGEPARAGDPPSLVRPAGFEIIVTNGSSINGPLVNGAARAGTEVYGLGVTGSTADGSAVLGIRLQGSDLTSVRVSDGAVLSGASLVGAVFATQAPGGAPIDLRIDTVSASPSRYHAGSAVSRYTLSYREGVSGLWRRVCGEVMGVPVAVIPLASRWSYGEGTAGGGAKLDEPDWITFACAGHALHKCVELGYEPWTTAAGAPLGDHHQACVRAYRADYCGDGSPHTTSGQLINLFDDLGVQPDTESWLMESEWDADGARCLSQPRMTGGVVPGCAAGLPVCHSTIGWGDTLVVTEAP
>NC_021658.1|WP_020735186.1|4540317_4544217_-|protein-kinase
MRVGDVLEGRFTLDARAGSGGMGEVFRARDDATGQAVAVKVMLARHTAERARFEREVRVLSELSHPAIVQFVAHGETPDGEPYLAMEWLEGEDLRARLARGMLGVDESVALAARVAAALGTAHARGVVHRDLKPSNLFLPAGDVALVKVLDFGIAHLGDVTRLTRTGAILGTPGYMAPEQAGGAGALDARADVFALGCVLYECLTGTPAFAGERLMAVLAKICCEEPLRVAALRAGVPPALDALVARMLAKQPDRRPRDGASVAAELSALDGDPRVARADPTPAGPLALTLAAGEPKVVSVVMLGRESPLWLDTTEVEAPPGTPAEHELRDTAALFGGRLDVLADGSAAVTISGDFVATDLAARAARCALALRAIRSSQPMALATGRSDASGAGLLGDAIDRAARLVARRGPVAQRILLDDVTAGLLDARFEVAAGEAGYELLGEREVIAGARALLGKRTACVGRARELSMLEGLLSECVDEPVARAVLVTAPAGVGKSRLCHEFLRAARARGAPIEVWIGRGDALRGGQAFGALGQALRGACEIREDDPPEARRDKLRARVARRVAQADRARVTWFLGELAGAPFPDDESAPLRAARAKAELMSEQVRRAWEDFLLAECAAGPVLLVLDDLHWADHATVRLVDAALWSARDLPFMVLASARPEVHERFPRLWAERELQEIRLGALTPKASEQLVRQVLGDGVSPDIVERLVSRSRGHAFYLEELIRAVAEGRDTLPETVAAMVQAWIERFEPEARRLLRTASVFGEVFWPGAVASLLGGEPDASDAGVELAARIDQLVQQEALVRQPESRFAGEPELAFRHALLAEGAYAMLPEDERVRGHRLAGAWLEERGESAPAVLADHFERGGERARAADLYRRAVEQAVLWGDTEAAITYARRGLACAPSDEHRLALLNVLWEAHLWGMDLASADVAGDAEQMMVLATPGSGPWARGALLKLFGLMATGQPEAFTATLSAVRAVGPLPDAAAAVAGTLQKGIVHLLTNGQPAVAQHLLRWLEAIVEPVAELDPRGRGLRDLARSFHVIYADEDPWSGLQWAEVALESLEQAGSQVDIARARAHVAMGLWLLGAYARAEQTVRKALLCADEEVWIAVGNHFLILGWILIGKGEIEEARLIAEAMIDAGRVRRVAFYEGMGRTLLAQALFERGDLETAEREALSALGALSSAPPRRLVLLRTLAAIRLAQGRVAEALADAEEALAGYEALRMFYSKGSLARLIHAEALMAAGDQRRALAAIAEARARLLENAAKIGDPELRRSFLEDVRENARTFELARAWLGEA

Crispr_ID: NC_021658_14

• CRISPR_ID: NC_021658_14
• CRISPR_location: 4698117-4698184
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_14

Consensus_repeat	Method
CCCGGAGGCTGCCGAGGGCCTCCCGG	CRISPRCasFinder

spacers of NC_021658_14

>14.1|4698143|16|NC_021658|CRISPRCasFinder
TAGAATTGAAATTCAC

CRISPR arrays and Neighbor proteins around NC_021658_14

CRISPR arrays

The CRISPR arrays of NC_021658_14

>merge|NC_021658|14|4698117-4698184|CRISPRCasFinder
CCCGGAGGCTGCCGAGGGCCTCCCGGTAGAATTGAAATTCACCCCAGAGGTTGCCGCAAGCCTTCGGT

>NC_021658|14|11|4698117-4698184|CRISPRCasFinder
CCCGGAGGCTGCCGAGGGCCTCCCGG	TAGAATTGAAATTCAC
CCCAGAGGTTGCCGCAAGCCTTCGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020735304.1|4701712_4702027_+|RNA-binding-protein	unknown	unknown	gnl|CDD|240845
NC_021658.1|WP_020735295.1|4689189_4689813_-|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl|CDD|366759
NC_021658.1|WP_044985896.1|4699411_4700347_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148313632.1|4684899_4686894_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_021658.1|WP_020735293.1|4687326_4687650_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187346049.1|4696873_4697752_+|glycoside-hydrolase-family-11-protein	unknown	unknown	gnl|CDD|366111
NC_021658.1|WP_020735302.1|4698311_4698986_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148313633.1|4700700_4701078_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735297.1|4691747_4692200_+|VOC-family-protein	unknown	unknown	gnl|CDD|213772
NC_021658.1|WP_020735294.1|4688488_4689193_-|uracil-DNA-glycosylase-family-protein	unknown	unknown	gnl|CDD|381683
NC_021658.1|WP_148313634.1|4705315_4705807_+|carboxypeptidase-regulatory-like-domain-containing-protein	unknown	unknown	gnl|CDD|379297
NC_021658.1|WP_020735299.1|4694842_4695856_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl|CDD|236515
NC_021658.1|WP_044985898.1|4707027_4708128_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735306.1|4702726_4703914_+|DTW-domain-containing-protein	unknown	unknown	gnl|CDD|377168
NC_021658.1|WP_020735305.1|4702334_4702517_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735309.1|4705803_4706943_+|di-heme-enzyme	unknown	unknown	gnl|CDD|188554
NC_021658.1|WP_020735307.1|4704423_4705272_+|metallo-mystery-pair-system-four-Cys-motif-protein	unknown	unknown	gnl|CDD|188567
NC_021658.1|WP_020735298.1|4692192_4694841_+|methylmalonyl-CoA-mutase	unknown	unknown	gnl|CDD|236508
NC_021658.1|WP_080682165.1|4696297_4696726_+|transposase	unknown	unknown	unknown
NC_021658.1|WP_044985895.1|4690147_4691647_+|peptidase	unknown	unknown	gnl|CDD|349460

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020735306.1|4702726_4703914_+|DTW-domain-containing-protein	gnl|CDD|377168	pfam03942, DTW, DTW domain. This presumed domain is found in bacterial and eukaryotic proteins. Its function is unknown. The domain contains multiple conserved motifs including a DTXW motif that this domain has been named after.	1.25366e-53
NC_021658.1|WP_020735295.1|4689189_4689813_-|rhomboid-family-intramembrane-serine-protease	gnl|CDD|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	3.99499e-20
NC_021658.1|WP_148313632.1|4684899_4686894_-|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	2.93712e-10
NC_021658.1|WP_044985895.1|4690147_4691647_+|peptidase	gnl|CDD|349460	cd06241, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavage. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	1.66044e-89
NC_021658.1|WP_020735304.1|4701712_4702027_+|RNA-binding-protein	gnl|CDD|240845	cd12399, RRM_HP0827_like, RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins. This subfamily corresponds to the RRM of H. pylori HP0827, a putative ssDNA-binding protein 12rnp2 precursor, containing one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain). The ssDNA binding may be important in activation of HP0827. .	1.64026e-28
NC_021658.1|WP_020735297.1|4691747_4692200_+|VOC-family-protein	gnl|CDD|213772	TIGR03081, Methylmalonyl-CoA_epimerase_mitochondrial, methylmalonyl-CoA epimerase. Members of this protein family are the enzyme methylmalonyl-CoA epimerase (EC 5.1.99.1), also called methylmalonyl-CoA racemase. This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase (TIGR00642). It is known in bacteria, archaea, and as a mitochondrial protein in animals. It is closely related to lactoylglutathione lyase (TIGR00068), which is also called glyoxylase I, and is also a homodimer.	1.37012e-31
NC_021658.1|WP_020735294.1|4688488_4689193_-|uracil-DNA-glycosylase-family-protein	gnl|CDD|381683	cd10033, UDG_like, uncharacterized family of the uracil-DNA glycosylase superfamily. Uracil-DNA glycosylases (UDGs) initiate repair of uracils in DNA. Uracil may arise from mis-incorporation of dUMP residues by DNA polymerase or via deamination of cytosine. Uracil in DNA mispaired with guanine is one of the major pro-mutagenic events, causing G:C->A:T mutations; thus, UDG is an essential enzyme for maintaining the integrity of genetic information. UDGs have been classified into various families on the basis of their substrate specificity, conserved motifs, and structural similarities. Although these families demonstrate different substrate specificities, often the function of one enzyme can be complemented by the other. UDG family 1 is the most efficient uracil-DNA glycosylase (UDG, also known as UNG) and shows a specificity for uracil in DNA. UDG family 2 includes thymine DNA glycosylase which removes uracil and thymine from G:U and G:T mismatches, and mismatch-specific uracil DNA glycosylase (MUG) which in Escherichia coli is highly specific to G:U mismatches but also repairs G:T mismatches at high enzyme concentration. UDG family 3 includes Human SMUG1 which can remove uracil and its oxidized pyrimidine derivatives from, single-stranded DNA and double-stranded DNA with a preference for single-stranded DNA. Pedobacter heparinus SMUG2, which is UDG family 3 SMUG1-like, displays catalytic activities towards DNA containing uracil or hypoxanthine/xanthine. UDG family 4 includes Thermotoga maritima TTUDGA, a robust UDG which like family 1, acts on double-stranded and single-stranded uracil-containing DNA. UDG family 5 (UDGb) includes Thermus thermophilus HB8 TTUDGB which acts on double-stranded uracil-containing DNA; it is a hypoxanthine DNA glycosylase acting on double-stranded hypoxanthine-containing DNA except for the C/I base pair, as well as a xanthine DNA glycosylase which acts on both double-stranded and single-stranded xanthine-containing DNA. UDG family 6 hypoxanthine-DNA glycosylase lacks any detectable UDG activity; it excises hypoxanthine. Other UDG families include one represented by Bradyrhizobium diazoefficiens Blr0248 which prefers single-stranded DNA and removes uracil, 5-hydroxymethyl-uracil or xanthine from it.	4.89731e-40
NC_021658.1|WP_148313634.1|4705315_4705807_+|carboxypeptidase-regulatory-like-domain-containing-protein	gnl|CDD|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	0.00388966
NC_021658.1|WP_020735299.1|4694842_4695856_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl|CDD|236515	PRK09435, PRK09435, methylmalonyl Co-A mutase-associated GTPase MeaB.	7.12037e-169
NC_021658.1|WP_020735309.1|4705803_4706943_+|di-heme-enzyme	gnl|CDD|188554	TIGR04039, MXAN_0977_Heme2, di-heme enzyme, MXAN_0977 family. This model describes a subfamily of di-heme proteins related to the di-heme cytochrome c peroxidase and to MauG (methylamine utilization G), an enzyme that performs a tryptophan tryptophylquinone modification to the methylamine dehydrogenase light chain.	0
NC_021658.1|WP_020735307.1|4704423_4705272_+|metallo-mystery-pair-system-four-Cys-motif-protein	gnl|CDD|188567	TIGR04052, hypothetical_protein_MettrDRAFT_3899, AZL_007920/MXAN_0976 family protein. Members of this rare protein family regularly occur next to a member of the MXAN_0977 subfamily (TIGR04039) of the di-heme cytochrome c peroxidase/MauG family (pfam03150). MauG itself (TIGR03791) is a protein modification enzyme responsible for the tryptophan tryptophylquinone (TTQ) modification involved in methylamine dehydrogenase activation. All members of this family have a motif of four spaced invariant Cys residues, while additional homologs outside the scope of this family lack the four Cys residues.	9.96321e-71
NC_021658.1|WP_020735298.1|4692192_4694841_+|methylmalonyl-CoA-mutase	gnl|CDD|236508	PRK09426, PRK09426, methylmalonyl-CoA mutase; Reviewed.	0
NC_021658.1|WP_187346049.1|4696873_4697752_+|glycoside-hydrolase-family-11-protein	gnl|CDD|366111	pfam00457, Glyco_hydro_11, Glycosyl hydrolases family 11.	1.253e-45

Protein sequences

>NC_021658.1|WP_187346049.1|4696873_4697752_+|glycoside-hydrolase-family-11-protein
MEPSGGSSSSSSSSSSSSSSSSSSSSSSSSSSSSSASSSSSSASSSGSAGGGDTTGPPLPDFSKYSAYTEQYTEKTVITSNHATGHVGDFFFTHWKDGGSTSLTVDPNGEFSVTWQGGGYNYVGGPGWHYGDENRVIGYRLNNDSGASYIALYGWGYDKTMPTSNPAHLVEYYILQRWSYDPSQGATPGKTFVSDGVEYSTYRSTRQQQPSINGRSTFYQYWSKPARPQALGQDHKIIFADHVKAWADTGWIVPNMNNLDASDDPTYQVMAVEVFNPGSNGTASGRVWDETP
>NC_021658.1|WP_080682165.1|4696297_4696726_+|transposase
MPKLSHLRSVDPTPAPAAQGAAPRPSGAAVESVAKPGKRRKFSAAEKLRIVREAAACTQRGDIDALLRREGIDSSLLAAWRKQLALHGSEALAERKPGHNPHDVPAARRLRRERGAARAAWADQSSRESVAQGTIARGWAKI
>NC_021658.1|WP_020735299.1|4694842_4695856_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MKPDPRQLVDGLVAGDRAALARAITLAESALPRHQELAEEVLELCLAHASHASPRAGGAVRLGVSGVPGVGKSTFVDALGVHLVREREETVAVLAVDPTSPVHGGSILGDKTRMPRLASDPRAFIRPSPSGGSLGGVARATRQAIALCEAAGYRNILVETVGVGQSEVAVADMTDCFLLLMLPGAGDELQGMKRGIMELVDLVIINKADGGSEGRAARARSEYEAALHLFPPPPHGWAPVVGVCSAQENRGVGEAWELVLRHRAHMQESGWLQRRRAAQARRWLVELIEGHLREAFLRSAAVRERMPGLEGLVEAGALSPLRAARQLLEAWEAAGKG
>NC_021658.1|WP_020735298.1|4692192_4694841_+|methylmalonyl-CoA-mutase
MDDRLFSEFAPVALETWRQALARDLKGKTADDLSWASAEGLLVPPIFAPDSPPLPAAEGGPLVESLVAELRGGASELRFTLGCGYFFEIARLRAARLLAERLRPGATLTAVIPSAAVPGDEPHKNLLRGIVAMMAAVAGGADDVVITPPERLLGNARVILREEAHFEAGGSPAAGCWYVEQLTRSLARAALRQIDGAAELPAPAAAPEAAAPLEHLGFTAGIPPFLRGPYTSMYVVRPWTLRQYAGYSTAEESNAFYRRNLAAGQTGLSVAFDLATHRGYDSDHPRVVGDVGKAGVAIDTVEDMKVLFDQIPLDKMSVSMTMNGAVLPVMAFYIVAAEEQGVRPELLSGTIQNDILKEFMVRNTYIYPPAPSMRIVADIFRFAAEKMPRFNSISISGYHMQEAGATAELELAYTLADGLEYLRTGIASGMDIDDFAGRFSFFFGIGMDHFTEIAKLRAARLLWAKIVKGFQPRSPKSMALRTHCQTSGWSLTEQDPFNNITRTAIEALAAVLGGTQSLHTNALDEALALPSDFSAKVARDTQLFLQRETDVCRVIDPWGGSHHVERLTDRLARRAWQFIQEVEALGGMVKAIENGLPKMRIEEAAARKQARIDAGRDIIVGVNAYRLEREAPLELREVDNSAVRERQVARLGAVKAARADAAVGEALAALTRAAATGEGNLLALAVDAARRRATLGEISEALERVFGRYEAPVRAVSGVYGAEIRDAGAGRDVEALVREFAALEGRRPRILVAKMGQDGHDRGMKVIATAFADLGFDVDIGPLFQTPDEVARHAVENDVHVVGVSSLAGGHKTLVPQLLDALGAAGRGDILVVAGGVIPPQDYRYLEERGVAGVFGPGTVIPDAAARIVRTLMDRLSAQEAR
>NC_021658.1|WP_020735297.1|4691747_4692200_+|VOC-family-protein
MKDQIPGFLFIDHVAMAVPAGQLDAQVQAYELLGFREVHREEVRGTDQVREVMLRVGDSDNHIQLLEPLSAESPVQKLIDKNGGRGGFAHVAYRVSDVQVAFDELKARGFRIIDVAPRPGSRGTTIFFMHPKSRDDAPFGHLIEVVEAHG
>NC_021658.1|WP_044985895.1|4690147_4691647_+|peptidase
MLLTRAEATGFRETSLHADVMRFVRALEARDDPRLAVTTFGTSPGGRELPLLVLSKDGVRSPAEARRAGRPVVLMLDGIHPGEVEGKEASLALVRDLLDGRHPDWLDTLVLLVVPLFNPDGNDALDPQNRRLDLKKLTGQPGPVVGTRTQSQGINLNRDYLRQAAPEMRLLQERVCIPWAPDLTIDNHATNGSVHRFHMTVDVPHTAESGRAEPIAMVRDRLVPEVMAAVRKRGFESGWYGNFVEDERALDAGGDADPAAPVGLGWMTYPHHPRFGSNYRGLTGRLDLLLECYSYLSFEERVHTASAWQIETLSWAAAHADAIREVVASSARPPDRVAVRYRLEPTATPIDVLTRSPRAFDGEPVTVRIPHLARFVGTTVVDRPRAYLVPPAIAEALRRHGLRVAPAEGVHDVEVARVASLGAEHGRAILEAAQVGEVAVEWRAEARRAPEGWSRIDTEQPLGAIAVYLCEPESDDGAAENGLVAAPAVGDEHPAWRVR
>NC_021658.1|WP_020735295.1|4689189_4689813_-|rhomboid-family-intramembrane-serine-protease
MSTSETRAITRELKLHSALLGGVVALLWAIEILDVAVFRGSLDALGIRPRTIPGLVGIALAPWLHGGFAHLIANTVPFVALGWLILLRKKSDLALVTLLSALVGGLGVWLIGSSSSVHIGASGVIFGYFGFLLLRGWFERSLLSIALSLVVGFVYGGMIWGVLPTRVGISWEGHLFGFLGGVLAARLLGGRLRAQAAGAAGRSMSTR
>NC_021658.1|WP_020735294.1|4688488_4689193_-|uracil-DNA-glycosylase-family-protein
MRRPALRLPVLSAEERPAAEERLAALHRELEACRACPKMIGPVVHGPPVPSRILLIGQAPGPREGSLGRPFAWTAGRTLFRWFEAALGVPEDELRRRVYMSAVARCFPGKAKGGGDRRPDPEEILRCRTHLAREVGILEPRLILPVGTLAVEQVLGHRGPLAGVIGEARRARFHGVEADVICLPHPSGASTWHKTEPGISLLGRALRLIAEHPEAARAFAGAAPAAAAASDEPP
>NC_021658.1|WP_020735293.1|4687326_4687650_-|hypothetical-protein
MLKILRKLNEGSLLQRTMMHIAVFVAGSASVVGLTSVLLVSTAKAVLPPHDATEAGADSADAEDEKGEKGADAEPGSPEAAARPAGARAGSKALARVANRREGAVAQ
>NC_021658.1|WP_148313632.1|4684899_4686894_-|CHAT-domain-containing-protein
MWLEVELDAGDQGLRVSARGSRGERPPARELLPEEGLDALQAFASKVGRAVRGGKPLDPAALGDAQRLYGELIDGDLRDVLVRLGEAAKESRLLVRLFARERALQVIPWEALCRPGTSEGFWGTDPRLLLARGVDSAEPWEPREVRGAVRMLAIAPGAHEQALAALRAALGASIESGEIEWLDPIAGPDVSPRVLFDRLRRGKTPHIVHFLGHGGVDASGKPMLRMADDEEGEEVWITAEALGRELSASFYEELRLVVLEACEGAKTGAFGSAAEVLGKAGADAVVAHLWPVKADVARVCSTEIYRALTGADRTAGDIGAAVAAARRTLLATSAEAFSPVLYLRGSDSVIFNFAGRRVSKPGAKRGSKRLAPALQGLLEGAFTMIVGDLDDDRAALRKDITSFMQENGDTRVEGLSLSTLTQRCVLRFGQEVLHSLFQQSLTQAQPAELPPLIEALARFVRPGVHVTLLWRPHLERAVAAAHPQRTVYAIQPSMVGSSGKPRVVKRAAGATSWKMEPLLPKRFDLESEIVVLRLYGGYSAEARPIFSPPILTDDDHIHGLLGAEGLRPPTWMQELLGKPRTQSGLFLGLSILDWRHRMFLRWLYDQRPAPKDSLVLLLPDAEPAEVEIWDSGAGLPGAARIAAITEDPAQLAPLLADIDPGEAR
>NC_021658.1|WP_020735302.1|4698311_4698986_-|hypothetical-protein
MSCPSKGSYRLGGAALVASGLLFLVRAVLDLIAGPPPSGGAEILAWTASRAPLLAIANEALFFAGMLMVPAIIALYSSLAGTDKRAAGAACGLMAVAAPVIAVLCIIHGRLVYPVYGIRIGTPDMAALVIALFYGGLHAISILLGAATLVLSLIMRRGIYGRWVAVLGIATSVADVVGAYPYIIGPVPALLCQVLFTAWFVAVGSVLYKMPDGAALERTAAPAL
>NC_021658.1|WP_044985896.1|4699411_4700347_+|hypothetical-protein
MRPLALSLAALALLLPLTAPALAEETVKEEDWAKARGFRLGVEADVLVSTIEASLPRREAASGGGASAGGEASSFAASFAAVAQIPLFAGLHLDAELPFAYGSSQARPPDAAVGDAATVAPELEGFFFGNPSIGLHYVASVFPTLMVIGGLSASIPITQDPSDDTAAAAAAALAVRGYFDAQRTLLEHVPLRARGGVELRPIEAFYVRSDLVAMFAIPTADGETEVFIEHASEAELRSLGGFGVGARLQAAFPLTRTDKVALAAEPFVGVEPPTSGLYFRAGLLVALDEPLGFGLEQGKLATVRVALGGKF
>NC_021658.1|WP_148313633.1|4700700_4701078_+|hypothetical-protein
MQKLGVFVICGFASISTLNGCTADTAPQSDSKQESPLASVPKNKDSQSKRARSQGESTRMTPYVFAAWRKCADEHQRCQFIGTHTVAYGAGDQWFYRTATNGIDCNNETFGDPAFGIFKACYITD
>NC_021658.1|WP_020735304.1|4701712_4702027_+|RNA-binding-protein
MGNRLYVGNLSYNTTRESLESAFSGTGEVREISMPTDRETGQLRGFAFVTMGSAQDANSAISQLNGLMLDGRALKVNEAQERPAGGGGGGRGGFGGGGGGRGRY
>NC_021658.1|WP_020735305.1|4702334_4702517_+|hypothetical-protein
MQRQTALKRQKERARIEKQREKTANRLERRNDKGPSGGLAPGEDPDIAGIVPGPQPPAVD
>NC_021658.1|WP_020735306.1|4702726_4703914_+|DTW-domain-containing-protein
MRDVCWRCRRPRPVCYCALLPSLPTRTRVVLLQHPRERRVGIGTARMTHLSLPNSELHEGVVFEDDPRIAALAADPTTAVLYPGGDARPADGAPVRSLIVVDGTWWQSRKMLALNPRLAAVRRIGVTPRAPGNYRIRREPRPECLATVEAVASALGALEGEPARFDAMLRAFAFMVDRQIEHQARSTAPRKRRAEAPPPLAPLRPHRADPARVVLVDGGANAGWLAADGAVEPGAVEPRSELVHLVACRASGERFEAFLRPRRPLGPSVAHQLDVPEARLRDGEDAGAALARFRAFVGDGVLGTWGVFTVDLLAQEGLRRPPFVDLRDLCMRHLRRRPGGIASGARALQAGEPAPRGAGRCGRTVGWLEVVLARLLELAEDNEAFGGQKRPAGGD
>NC_021658.1|WP_020735307.1|4704423_4705272_+|metallo-mystery-pair-system-four-Cys-motif-protein
MARVTFLSVACLAALSGCGEGDEDVASKTFALSFAAKVGDEPFSCTTTFDGVGTTRSAVKPLDFRMYVYDVRLVRDDGSEEPLSLEQDGSWQRDKVAFLDFEDGTGTCETGSPETRTEIVGTAPAGDYAGVRFNLGLPPEMNHLDAATAPAPLNIPGMWWSWKGGYKFVRLDLISTMNPTYFFHLGGTKCEGTVSEGFSCAADNVADVRLDGVDPGSSTIVFDIASFYAESDLDHQVDGMTDRTSGCMSFEGDPECPPVFKALGMGFDGASPSAPQTAFRVE
>NC_021658.1|WP_148313634.1|4705315_4705807_+|carboxypeptidase-regulatory-like-domain-containing-protein
MICALAGCGASDEEMDEPSDAEVLPGDPRFERDPALDVDNVSAAEEKRSHNMGQNCMGCHQPHGPGKGLFTAAGTVYAPSGTPVAGGTVELRTAAEGEGDLVLSVAIDGNGNFFTTEPLPFPDQALFFLLRAPAGGGTNNMPFPSISGACNLCHNEQRRILVE
>NC_021658.1|WP_020735309.1|4705803_4706943_+|di-heme-enzyme
MTRASTSAALLALAAASCGGETEAIPPADSYELALPVGFPRPWVPPDNPMTEAKVALGRALFFDKRLSGNGTMACASCHEPDRGLADGKVTPIGSTGDAIPRNAMGLANIAYFPLLTWGNPTLSSLEEQALVPMFGESPVELGITGAEDVVLGRLRGDDAYKAAFAAAFPGEREPITLDTVVKAIATFERTLISGRSAYDRSTYGGEADAMSEAALRGMDLFFSERLECYHCHSGINFTTAFRSAETKQAEMDFHNTGLYNLGRDGGYPPGGEGLFEFTGDPADKGKFRVPSLRNVELTAPYMHDGSVATLEEVVDHYAAGGRTIDDGPFAGVGSKNPNKSSLIRGFTITPEEKADVVAFMKSLTDPEFAAVVDGAQAP
>NC_021658.1|WP_044985898.1|4707027_4708128_-|hypothetical-protein
MKERIAGPRSSRAEALARTKTSFYAASALLLSAAMVGCIGSLDEVDVAGASLEEGRAEGALESRDGSGDDAAPGGSTSAPTLACAPLCNGSCTPIDLATVNTNGALQIALTDQYVYYGGGYGSEVGDDEVGRVPKAGGAKSILIDRLTYVTELVGSGPYAYFAGSGPGLGSKLNRVNPDGTITALPIAGGYPSGVAVDSTRIYWIGNNRYDIYARPLSGGTPSVVVPRGGGLRTSLFEDGDSLYYREIASSGIMTAPKSGAAAPTRFIPRLTWYLDFDEANVYYAANGVYRMPKSGGTPVQLATGGTRVVVDNERIYWLDGTALRAMCKDGTGTQVLASTGEHYDLAVDGTGVYWAGEGKIRKIAK

Crispr_ID: NC_021658_15

• CRISPR_ID: NC_021658_15
• CRISPR_location: 4716152-4716246
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_15

Consensus_repeat	Method
CGGGCCTGACTCGACGAGATGCC	CRISPRCasFinder

spacers of NC_021658_15

>15.1|4716175|49|NC_021658|CRISPRCasFinder
CTCTGGAGCACCGGCGGTGTGTTACCGATCGTAACGGGATCTCACCGGC

CRISPR arrays and Neighbor proteins around NC_021658_15

CRISPR arrays

The CRISPR arrays of NC_021658_15

>merge|NC_021658|15|4716152-4716246|CRISPRCasFinder
CGGGCCTGACTCGACGAGATGCCCTCTGGAGCACCGGCGGTGTGTTACCGATCGTAACGGGATCTCACCGGCCGGTCCTGACTCGACGAGATGCC

>NC_021658|15|12|4716152-4716246|CRISPRCasFinder
CGGGCCTGACTCGACGAGATGCC	CTCTGGAGCACCGGCGGTGTGTTACCGATCGTAACGGGATCTCACCGGC
CGGTCCTGACTCGACGAGATGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020735320.1|4725995_4728563_-|polynucleotide-kinase-phosphatase	unknown	unknown	gnl|CDD|274963
NC_021658.1|WP_020735306.1|4702726_4703914_+|DTW-domain-containing-protein	unknown	unknown	gnl|CDD|377168
NC_021658.1|WP_044985898.1|4707027_4708128_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735315.1|4718060_4719059_-|HupE/UreJ-family-protein	unknown	unknown	gnl|CDD|379373
NC_021658.1|WP_049949532.1|4730509_4731787_+|cellulose-binding-domain-containing-protein	unknown	unknown	gnl|CDD|226755
NC_021658.1|WP_080682170.1|4721723_4723391_-|hypothetical-protein	unknown	unknown	gnl|CDD|379155
NC_021658.1|WP_148314810.1|4732201_4733209_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NC_021658.1|WP_020735313.1|4713035_4716071_+|PAS-domain-containing-protein	unknown	unknown	gnl|CDD|236901
NC_021658.1|WP_148313634.1|4705315_4705807_+|carboxypeptidase-regulatory-like-domain-containing-protein	unknown	unknown	gnl|CDD|379297
NC_021658.1|WP_187345967.1|4708717_4711105_+|EF-hand-domain-containing-protein	unknown	unknown	gnl|CDD|163523
NC_021658.1|WP_044988327.1|4711506_4712490_+|macrolide-2'-phosphotransferase	unknown	unknown	gnl|CDD|270701
NC_021658.1|WP_044985899.1|4720059_4721301_-|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|200589
NC_021658.1|WP_020735305.1|4702334_4702517_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735309.1|4705803_4706943_+|di-heme-enzyme	unknown	unknown	gnl|CDD|188554
NC_021658.1|WP_049949531.1|4712586_4713039_+|hypothetical-protein	unknown	unknown	gnl|CDD|237171
NC_021658.1|WP_148313635.1|4719055_4719874_-|hypothetical-protein	unknown	unknown	gnl|CDD|379040
NC_021658.1|WP_020735307.1|4704423_4705272_+|metallo-mystery-pair-system-four-Cys-motif-protein	unknown	unknown	gnl|CDD|188567
NC_021658.1|WP_020735321.1|4728559_4730071_-|3'-terminal-RNA-ribose-2'-O-methyltransferase-Hen1	unknown	unknown	gnl|CDD|274962
NC_021658.1|WP_020735319.1|4723655_4725647_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173798
NC_021658.1|WP_020735314.1|4716510_4717896_+|MHS-family-MFS-transporter	unknown	unknown	gnl|CDD|340927

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020735320.1|4725995_4728563_-|polynucleotide-kinase-phosphatase	gnl|CDD|274963	TIGR04075, Ser/Thr_phosphatase_family_protein, polynucleotide kinase-phosphatase. Members of this protein family are the bacterial polynucleotide kinase-phosphatase (Pnkp) whose genes occur paired with genes for the 3' terminal RNA ribose 2'-O-methyltransferase Hen1. All members of the seed alignment belong to a cassette with the Hen1. The pair acts in bacterial RNA repair. This enzyme performs end-healing reactions on broken RNA, preparing from the RNA ligase to close the break. The working hypothesis is that the combination of Pnkp (RNA repair) and Hen1 (RNA modification) serves to first repair RNA damage from ribotoxins and then perform a modification that prevents the damage from recurring. [Transcription, RNA processing].	0
NC_021658.1|WP_020735306.1|4702726_4703914_+|DTW-domain-containing-protein	gnl|CDD|377168	pfam03942, DTW, DTW domain. This presumed domain is found in bacterial and eukaryotic proteins. Its function is unknown. The domain contains multiple conserved motifs including a DTXW motif that this domain has been named after.	1.25366e-53
NC_021658.1|WP_020735307.1|4704423_4705272_+|metallo-mystery-pair-system-four-Cys-motif-protein	gnl|CDD|188567	TIGR04052, hypothetical_protein_MettrDRAFT_3899, AZL_007920/MXAN_0976 family protein. Members of this rare protein family regularly occur next to a member of the MXAN_0977 subfamily (TIGR04039) of the di-heme cytochrome c peroxidase/MauG family (pfam03150). MauG itself (TIGR03791) is a protein modification enzyme responsible for the tryptophan tryptophylquinone (TTQ) modification involved in methylamine dehydrogenase activation. All members of this family have a motif of four spaced invariant Cys residues, while additional homologs outside the scope of this family lack the four Cys residues.	9.96321e-71
NC_021658.1|WP_049949532.1|4730509_4731787_+|cellulose-binding-domain-containing-protein	gnl|CDD|226755	COG4305, COG4305, Endoglucanase C-terminal domain/subunit and related proteins [Carbohydrate transport and metabolism].	1.33319e-17
NC_021658.1|WP_148314810.1|4732201_4733209_+|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	4.62386e-40
NC_021658.1|WP_020735313.1|4713035_4716071_+|PAS-domain-containing-protein	gnl|CDD|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	1.1048e-59
NC_021658.1|WP_148313634.1|4705315_4705807_+|carboxypeptidase-regulatory-like-domain-containing-protein	gnl|CDD|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	0.00388966
NC_021658.1|WP_187345967.1|4708717_4711105_+|EF-hand-domain-containing-protein	gnl|CDD|163523	TIGR03811, tyrosine_decarboxylase, tyrosine decarboxylase, Enterococcus type. This model represents tyrosine decarboxylases in the family of the Enterococcus faecalis enzyme Tdc. These enzymes often are encoded next to tyrosine/tyramine antiporter, together comprising a system in which tyrosine decarboxylation can protect against exposure to acid conditions. This clade differs from the archaeal tyrosine decarboxylases associated with methanofuran biosynthesis. [Cellular processes, Adaptations to atypical conditions].	1.56547e-117
NC_021658.1|WP_044988327.1|4711506_4712490_+|macrolide-2'-phosphotransferase	gnl|CDD|270701	cd05152, MPH2', Macrolide 2'-Phosphotransferase. MPH2' catalyzes the transfer of the gamma-phosphoryl group from ATP to the 2'-hydroxyl of macrolide antibiotics such as erythromycin, clarithromycin, and azithromycin, among others. Macrolides penetrate the bacterial cell and bind to ribosomes, where it interrupts protein elongation, leading ultimately to the demise of the bacterium. Phosphorylation of macrolides leads to their inactivation. Based on substrate specificity and amino acid sequence, MPH2' is divided into types I and II, encoded by mphA and mphB genes, respectively. MPH2'I inactivates 14-membered ring macrolides while MPH2'II inactivates both 14- and 16-membered ring macrolides. Enzymatic inactivation of macrolides has been reported as a mechanism for bacterial resistance in clinical samples. MPH2' is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	2.2355e-110
NC_021658.1|WP_044985899.1|4720059_4721301_-|polysaccharide-deacetylase-family-protein	gnl|CDD|200589	cd10967, CE4_GLA_like_6s, Putative catalytic NodB homology domain of gellan lyase and similar proteins. This family is represented by the extracellular polysaccharide-degrading enzyme, gellan lyase (gellanase, EC 4.2.2.-), from Bacillus sp. The enzyme acts on gellan exolytically and releases a tetrasaccharide of glucuronyl-glucosyl-rhamnosyl-glucose with unsaturated glucuronic acid at the nonreducing terminus. The family also includes many uncharacterized prokaryotic polysaccharide deacetylases, which show high sequence similarity to Bacillus sp. gellan lyase. Although their biological functions remain unknown, all members of the family contain a conserved domain with a 6-stranded beta/alpha barrel, which is similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, belonging to the larger carbohydrate esterase 4 (CE4) superfamily.	1.44165e-15
NC_021658.1|WP_080682170.1|4721723_4723391_-|hypothetical-protein	gnl|CDD|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	3.14762e-25
NC_021658.1|WP_020735309.1|4705803_4706943_+|di-heme-enzyme	gnl|CDD|188554	TIGR04039, MXAN_0977_Heme2, di-heme enzyme, MXAN_0977 family. This model describes a subfamily of di-heme proteins related to the di-heme cytochrome c peroxidase and to MauG (methylamine utilization G), an enzyme that performs a tryptophan tryptophylquinone modification to the methylamine dehydrogenase light chain.	0
NC_021658.1|WP_049949531.1|4712586_4713039_+|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	1.75713e-06
NC_021658.1|WP_148313635.1|4719055_4719874_-|hypothetical-protein	gnl|CDD|379040	pfam13145, Rotamase_2, PPIC-type PPIASE domain.	0.00134324
NC_021658.1|WP_020735315.1|4718060_4719059_-|HupE/UreJ-family-protein	gnl|CDD|379373	pfam13795, HupE_UreJ_2, HupE / UreJ protein. These proteins contain many conserved histidines that may be involved in nickel binding.	5.70304e-48
NC_021658.1|WP_020735321.1|4728559_4730071_-|3'-terminal-RNA-ribose-2'-O-methyltransferase-Hen1	gnl|CDD|274962	TIGR04074, Methyltransferase_type_12, 3' terminal RNA ribose 2'-O-methyltransferase Hen1. Members of this protein family are bacterial Hen1, a 3' terminal RNA ribose 2'-O-methyltransferase that acts in bacterial RNA repair. All members of the seed alignment belong to a cassette with the RNA repair enzyme polynucleotide kinase-phosphatase (Pnkp). Chemically similar Hen1 in eukaryotes acts instead on small regulatory RNAs. [Transcription, RNA processing, Protein synthesis, tRNA and rRNA base modification].	0
NC_021658.1|WP_020735319.1|4723655_4725647_-|S8-family-serine-peptidase	gnl|CDD|173798	cd05562, Peptidases_S53_like, Peptidase domain in the S53 family. Members of the peptidase S53 (sedolisin) family include endopeptidases and exopeptidases. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of Asn in subtilisin. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values. Characterized sedolisins include Kumamolisin, an extracellular calcium-dependent thermostable endopeptidase from Bacillus. The enzyme is synthesized with a 188 amino acid N-terminal preprotein region which is cleaved after the extraction into the extracellular space with low pH. One kumamolysin paralog, kumamolisin-As, is believed to be a collagenase. TPP1 is a serine protease that functions as a tripeptidyl exopeptidase as well as an endopeptidase. Less is known about PSCP from Pseudomonas which is thought to be an aspartic proteinase.	8.02613e-51
NC_021658.1|WP_020735314.1|4716510_4717896_+|MHS-family-MFS-transporter	gnl|CDD|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.36376e-151

Protein sequences

>NC_021658.1|WP_020735313.1|4713035_4716071_+|PAS-domain-containing-protein
MIDVGVLLFATVAWLAVLAAIALAAQRERIPRALARHPLVLALSLGVYASSWTYYGGVGFAQRHGLVFLAVYLGPTLACMATPLLWSRVLHITREQRLSSLADLLAFRFQSPAAGALVAAFSLVASLPYVAQQFRATEASVRVLSGPGHEEAVGAVFCALLALFTAFFGARPSAERRREDGLAAAVAFESAAKLAVLAAVGLVAVLGAFGGASGLAGWLREHAAEVEALARPVREDRGWTSMLVISFAAAFLLPRQWHMAFASGAGDRALARAAWAFPLFLLALNLPVLPILWAGTRLAPAGPADSYVLLVPQLLDQRWLALAAFIGGISAASAMVMVTAVALANDSATHLLLPLARRTLRRNVYARVLWMRRGLLTAILVGGWLFHRAQANRGLLVESGIVSFVAFAQLLPGLFAVLFWERATRAGFIAGLLAGMASWTALCLAPLLPGMPGLDPAWLGLLLEGADPGVRAARAARALPMDTWSLPTFVSLAVNVGTLALVSLLRPPVKAEREAARLCRRREIGPSVERATVASSVGALEERLARLLGREAAGIEVTRARIELDIPRDETRPTELHALQERLHRNLSPLVGPVLARTVAEEAGAPAAAPGAGGALTEELRWLERRLARGETRLVGAARELDLLRRWLRSVLAQLPLGVCAVGSDGAVSLVNRRLEALVGVEERDLVGAPLDRLPAPFAELFARAVRAASAGEAGAGAEEIEAHVAGRARSLRVHRAALDPLDARAASGGVVLLVEDRTEQRALEAQLAHKDRLAQLGRLAAGVAHEVGNPLTGIACLAQNLRAEADSDEIRARAGLILGEAARIEAILRTLLEHSRTGAVPSPGEGTRARVGRVSLAQVIAEAERLLRLDRAAPHVRVEQACPESLVVVGDRRELVQVFVNLLANARDASGAGATIAVRGRIEAGEIVVEVEDHGSGIPEELLAAVFEPFVTTKRDPSGTGLGLPLSRSIVQDHGGTLTLRSAVGQGTTVVVRLPLAGAPGARRGPEAAP
>NC_021658.1|WP_049949531.1|4712586_4713039_+|hypothetical-protein
MRGGHDAEASAADRALVLALLGAVLLVSPARLLWARGPLAVAAVFAVWVALIALAWLATRADRGDADRGDADRGDADRGDGARGDGARGDADRGDADRGDGARGDGARGDADRGDADRGDGARGDGARGDADRGDADRGDGARGEREPPP
>NC_021658.1|WP_044988327.1|4711506_4712490_+|macrolide-2'-phosphotransferase
MTERTQPPSPSPSSFAPIDSVAALLDAARREGLRLVASQEGFDQSGLDFLAVHARDEEGVPWIVRTPRRAAVVEAARVEARVLALVRGRLPVAVPDWRVHTDQVIAYPRLVDVPAITFDPEAGMRWNRVDPAAPSEAFIASVADALAALQRVDVAAIAAAGVPVKSIDDTRQLHARAMDETRAALSPPDALWARWQRWLANDAIWPRHLALVHGDLHPGHMLLDEGGRLTGILDWTEAHLGDPSVDFALLAGAFSKAAFDACVARFEAAGGATWPGFAAHAQERWAAWPAMAAKWGMDTGNEGVIAHARSMLGQIAAEGGGAVQGAG
>NC_021658.1|WP_187345967.1|4708717_4711105_+|EF-hand-domain-containing-protein
MSGRASNDRSRMKQYLQFGDGPFLKGAGTRAPEAWFLGPKAENADELERLIVEAIRDHSFWRRNFHPQDPTHITEQSKRHPAYLHAMDSLKDNFRSLMSFLKKSVPFFSDRYQGHMNWDTSIPSVLGYFAAMLYNPNNVAFEGSTATTILEMIVGDDLCRMLGYALPDEDAGDKAVRPWGHITCGGTVANIEAIWSARNLKFYPLSLRDALKSEPSLSAARELVVTTCDGRRALLGALDAWSLLNLKVDEILALPARLTQEYGISSDTITAAMAGHSLQHLGIQELYRRCGADLPCSPVLLVPATKHYSFPKAAAVLGIGSANVLDIPVDCDARMSLSALEATLKRCLDERRPVYTVVSVVGSTEESAVDPLKGILELRHRFQKEGLSFTVHADAAWGGYFASMLRPDEGPRAKDAPSGPAAEVGMSRYVTAQLAALGRADSITVDPHKSGYVPYPAGALCYRNSAMRDMVTFKAPYIVHGDAEPTVGIYGLEGSKPGAAVAAVYLSHKVIRPTRSGYGQLHRKALFNCKRFYARLLCLARPEDRFIIVPVPRLPAEIGGGDAESELQFIRERINQPILEELLADPEAMALLPELGPDQNILTYAVNFKHPDGSINTSLDMMNRLNKAIYDLLSIAPGDDIYHYRMIVSTTDFSEEHYGKVFIEDYKRRLGVSASPGSTVTVLRSTMMAPWLLESPEGSILDVLESELRDAIFKAMMRDSMLQVFEEIDTNRDGTLDVAEIMAKFREKGFQDGDIDEFLQVCDVDRNGSVSVSEFLGAFSHFLVKAKLSAREAKV
>NC_021658.1|WP_044985898.1|4707027_4708128_-|hypothetical-protein
MKERIAGPRSSRAEALARTKTSFYAASALLLSAAMVGCIGSLDEVDVAGASLEEGRAEGALESRDGSGDDAAPGGSTSAPTLACAPLCNGSCTPIDLATVNTNGALQIALTDQYVYYGGGYGSEVGDDEVGRVPKAGGAKSILIDRLTYVTELVGSGPYAYFAGSGPGLGSKLNRVNPDGTITALPIAGGYPSGVAVDSTRIYWIGNNRYDIYARPLSGGTPSVVVPRGGGLRTSLFEDGDSLYYREIASSGIMTAPKSGAAAPTRFIPRLTWYLDFDEANVYYAANGVYRMPKSGGTPVQLATGGTRVVVDNERIYWLDGTALRAMCKDGTGTQVLASTGEHYDLAVDGTGVYWAGEGKIRKIAK
>NC_021658.1|WP_020735309.1|4705803_4706943_+|di-heme-enzyme
MTRASTSAALLALAAASCGGETEAIPPADSYELALPVGFPRPWVPPDNPMTEAKVALGRALFFDKRLSGNGTMACASCHEPDRGLADGKVTPIGSTGDAIPRNAMGLANIAYFPLLTWGNPTLSSLEEQALVPMFGESPVELGITGAEDVVLGRLRGDDAYKAAFAAAFPGEREPITLDTVVKAIATFERTLISGRSAYDRSTYGGEADAMSEAALRGMDLFFSERLECYHCHSGINFTTAFRSAETKQAEMDFHNTGLYNLGRDGGYPPGGEGLFEFTGDPADKGKFRVPSLRNVELTAPYMHDGSVATLEEVVDHYAAGGRTIDDGPFAGVGSKNPNKSSLIRGFTITPEEKADVVAFMKSLTDPEFAAVVDGAQAP
>NC_021658.1|WP_148313634.1|4705315_4705807_+|carboxypeptidase-regulatory-like-domain-containing-protein
MICALAGCGASDEEMDEPSDAEVLPGDPRFERDPALDVDNVSAAEEKRSHNMGQNCMGCHQPHGPGKGLFTAAGTVYAPSGTPVAGGTVELRTAAEGEGDLVLSVAIDGNGNFFTTEPLPFPDQALFFLLRAPAGGGTNNMPFPSISGACNLCHNEQRRILVE
>NC_021658.1|WP_020735307.1|4704423_4705272_+|metallo-mystery-pair-system-four-Cys-motif-protein
MARVTFLSVACLAALSGCGEGDEDVASKTFALSFAAKVGDEPFSCTTTFDGVGTTRSAVKPLDFRMYVYDVRLVRDDGSEEPLSLEQDGSWQRDKVAFLDFEDGTGTCETGSPETRTEIVGTAPAGDYAGVRFNLGLPPEMNHLDAATAPAPLNIPGMWWSWKGGYKFVRLDLISTMNPTYFFHLGGTKCEGTVSEGFSCAADNVADVRLDGVDPGSSTIVFDIASFYAESDLDHQVDGMTDRTSGCMSFEGDPECPPVFKALGMGFDGASPSAPQTAFRVE
>NC_021658.1|WP_020735306.1|4702726_4703914_+|DTW-domain-containing-protein
MRDVCWRCRRPRPVCYCALLPSLPTRTRVVLLQHPRERRVGIGTARMTHLSLPNSELHEGVVFEDDPRIAALAADPTTAVLYPGGDARPADGAPVRSLIVVDGTWWQSRKMLALNPRLAAVRRIGVTPRAPGNYRIRREPRPECLATVEAVASALGALEGEPARFDAMLRAFAFMVDRQIEHQARSTAPRKRRAEAPPPLAPLRPHRADPARVVLVDGGANAGWLAADGAVEPGAVEPRSELVHLVACRASGERFEAFLRPRRPLGPSVAHQLDVPEARLRDGEDAGAALARFRAFVGDGVLGTWGVFTVDLLAQEGLRRPPFVDLRDLCMRHLRRRPGGIASGARALQAGEPAPRGAGRCGRTVGWLEVVLARLLELAEDNEAFGGQKRPAGGD
>NC_021658.1|WP_020735305.1|4702334_4702517_+|hypothetical-protein
MQRQTALKRQKERARIEKQREKTANRLERRNDKGPSGGLAPGEDPDIAGIVPGPQPPAVD
>NC_021658.1|WP_020735314.1|4716510_4717896_+|MHS-family-MFS-transporter
MAQTSPEILAVTPPIRAREAGREVVDSGTLWKVIFASAGGTMIEWYDFYIFGSLAAIISTHFFPKDNPTAGFLLTLGTFATGFVVRPFGALVFGRIGDIVGRKYAFLVTLLLMGGATSLIGILPTYESAGLVAPLALVLIRLVQGLALGGEYGGAAVYVAEHAPDEKRGFYTSFIQITATLGLFVSLAVILGSRLIVGEDAFKEWGWRVPFLLSVLLVGVSFYVRVRLKESPIFAKLKAEGKTSAAPIKDSLGNKRNWKVILIALFGATAGQGVVWYTGQFYALYFLQNTLKVPFITSTIVVAAALALGMPFFVFFGALSDRIGRKKIMIAGNLCGAIGFFPVFWAMKQNADSPVVLTLLVFVLVLFVTMVYGPIAAYLVEAFPAKVRYTSLSIPYHVGNGVFGGLLPLIASSVTVATGNIYAGLLYPIGVALITVVVGGIFLKERSDVRLWDELERPRES
>NC_021658.1|WP_020735315.1|4718060_4719059_-|HupE/UreJ-family-protein
MNRLWLLRLAWSLPLLLTVLLAPAPAKGHELNSASLSLTEVEGREGRFLVRWEASSSTLKSELAAPAVFPPPCKLDGEFLDCGPAGLVGTIELPWLEGTETNVMVAIAWRSGSRLLRVLTGSDPSFVVYGIPASAGLLALKPIVVDYTRLGVEHILTGFDHLLFVIALTLLVRGGRKLVGAVTAFTVAHSLTLACAVFGWLTLPAPPVEATIALSIVLVCGECLRPADSLAHRAPWAVTFSFGLLHGLGFASSLLDIGLPEKHVPTALLFFNVGVEIGQLGVIALVLALSLLAARVPVQPATVRRGLVYAMGGMAGYWSVERIVATLTGASL
>NC_021658.1|WP_148313635.1|4719055_4719874_-|hypothetical-protein
MSDTTGRPMGSFARLLREPVVHFLFIGALLFLAHRLIVGDPRVVVVSGGLKADVERRFRDETGRAPTEAELQTALDRWKRDEALYREALREGLDRQDATVRTVLADKLRARAAQQTPAREPTDAELDAWLAAHRSQYETPLRYSFEVVAFPKSDPEAETQRSTYRRALADGADPKTLGRPIAGGNLTRDKLAAKFGPAVSESMCNLPLATWQPLETGDSLLLARVNRIEGGLPSREAIRATLVADWVAARKKQAADDFVESVVARYRFEEAP
>NC_021658.1|WP_044985899.1|4720059_4721301_-|polysaccharide-deacetylase-family-protein
MLKQPFGNFSSSPVLGALLLLGALHIGGCGDDGDGGSGGDGGQAATTTTSGTTGSVTSGGPGGTTSASTGGTGGDASTSTSTTAGTGGAGGEGGSGDGGSGGEAPPIDSGLPAPPGPDNVAKPSGAAGGLKVIDWAGFAGAVTYSFDDVNQTQIQNYDALKALGVPFTFYVWTGKSEANNPVWTQALMDGHELGNHTNRHDSNDTGSDTDIATKFIKDKWGVTPYTMAAPNGSEAYVTVAQSRFLINRGVSNALIGPNDNTNPFRLPTYIPPQNASTAQMDAEVSSARSQKKWRTFCIHGFTGGSDGAYQPIPLNAFLEHVKHVKDFGDVWIGTMEDVGAYWLGQKAVTDGDSNQSGGETTVTWQLPANFPPGKYVRVTVTGGTLKQNGAALPWNPHGFYEVALDPKSLTLSP
>NC_021658.1|WP_080682170.1|4721723_4723391_-|hypothetical-protein
MRTPMHTGSLSVAVALLASLAGCVAPDPLDEAEGEAVDTASGALVADRASLPTPAAYWSFDTCTDGTNARVREDSGRGAFGVMSGRGLCSPGKFLSAGDFNGAGDQVEISSAGRSYLHFQDRITAAAWVNPRSVTGLRTIVNQWYAADSFLLGIAQGKYFFSVAFPNGGAGQHVIVETPAVADAWAHVAGVYDGAALRLYVNGELRASTPASGTLQQSTRPIVIGGHPAWNAYDGLIDEVRLYQQALSSTQVAQLAAGEVYPVRAYYVYPNDQPYHQEYVDAINTTLAELQGWYRQQSNVSFHLVGSVQAVRSSQNYVNMRCGSSPSSACQNDPIEIPNWLNAVSQAVGGFPARQSTLVFSQGGGGYAGANLYGDYTGFAVVGDWVLEPISGVREPLAIHCGYATWQCLDGTPKGTVAHELGHSLGLHHPDSYPGESIMGWHGGYPTTIFFDHEQMILQESPMLSSGVLVRGGLWLDFGNADTMYSNTTVTLTGSGFGPGAQVEFVDATHTAVVSPTTISGTSLTVQVPSGLGPGYIRVRNGSGASNKVAVNFYP
>NC_021658.1|WP_020735319.1|4723655_4725647_-|S8-family-serine-peptidase
MKLWGISACALSMVLIGCVGEPSWEEETDLEQTAQALHEQKRDLMSGPGAKLGPHLRALQRAAEAHPSADEAAFDRKFPTLRVHDGYVAVSAYGDDGAALAAQLAREGMLDARVHDESVSGRVPIARLGAIAAMSDLRYMTPTMATTQAGLVTTQGDRSLRSDVARARFGVDGRGVRVGVLSDSFDCRGEPLLPGQMFTDAAQDIRNDDLPRDTVVLQDVDRTTFPDCIDEGRAMMQIIHDVAPGASLSFHTALFSQEDFAAGIIELADNGAKIIVDDIIYFAEPMFEDGVVADAVDEVFKRGVAYFSAAGNLARQSYQSRFRDSGRAGDSGGRRHDFDPGPRVDDLQRVSAGARSITQLAFNWDQPSLSANGRRGSRSDVDLIFYHENGEPVERCTTAPTQLVCQIPGIANNLGGDAVEVPVLVNGSDEDMVFKIGIELIAGPKPDLMKYVWFNIEGTFSVDEFDTRSSTMYGHMNAAGAEAVGAAAWFQTEEWGPLTPACVPACLESFSSVGGTPILFDDRGRRLPIPDVRLKPGVTGPDGGNTTFFFAPITVEIPGSTEPDQFPNFFGTSASAPHVAAVAALMLDARARDVAAGTSILGAHRLPPSLVYLVLRLTAEDMRLRDLGGEIGPVPVEGARGFDFETGFGFVDAVRALRAVLSL
>NC_021658.1|WP_020735320.1|4725995_4728563_-|polynucleotide-kinase-phosphatase
MSEPKPLVVPSLSLVVLVGASGSGKSTFARAHFKPTEILSSDHYRGVVSDDENDQAASADAFEVLRFIAGKRLAAGRLTVIDATNVQPDARRPLVALAREHHVLPVAIVLDLPEKLCHARNAGRPDRQFGPHVVRGQSRELRRSLRDLRREGFRYVHVLSSPEEVAAATIERQRLWTDRRDDHGPFDIIGDVHGCFDELVELLEALGYRLEGLPDAPRASHPEGRRALFLGDLVDRGPRSPDVLRLAMAMVASGAALCVPGNHDVKLLKKLRGRDVRPTHGLELTLAQLEVETDEFKAKAADFIDGLVSHYVLDDGNLAVAHAGVKEAFQGRGSGAVREFCLYGETTGETDEYGLPVRYNWASEYRGKAMVVYGHTPTTVAEWENRTICIDTGCVFGGALTALRYPERELVEVKARRVYYEPKKPLAPRGAEPKADPRGPADDALDIDDIRGRRAIRTRVHGMVTIREENAAAALEAMSRFAVDPRWLIHLPPTMSPSETSKDGGLLEHPREAFAYFRQNGVGRVVCEEKHMGSRAVLVVCRDEAARRRRFRLDDGPLGVCVTRTGRPFFADEARSRELIDRVRAAMDRADLWAELRTDWVCLDAELLPWSAKAQDLLRGQYAAVGASGRASLDAAVRALELAAARDESARPLLERHAARKAAMDGYVAAYRRYCWPVRSIADLRLAPFHLLASEGAVHASRDHGFHLRQLGRLCEVDPAFFVPTPHRVVDLSDPASEAQAVAFWTEMVERGGEGMVVKSWEWVVRGPRGLVQPAIKCRGPEYLRIIYGPEYLMPQHLARLRHRSVSAKRALALREYALGLEALHRFVEGEPLYRVHECVFGVLALESEPIDPRL
>NC_021658.1|WP_020735321.1|4728559_4730071_-|3'-terminal-RNA-ribose-2'-O-methyltransferase-Hen1
MLLTLTTTHRPATDLGYLLVKNPAHTQSFALSFGKAHVFYPEATEERCTAALLLDVDPVDLVRGRGGGEPGTLAQYVNDRPYVASSFLSVAIAQVFGSALGGKCRDRPELADAPLPLSATIEALPCRGGEGMLRRLFEPLGYEVAAERLPLDEAFPDWGQSAYLRVSLARTCRLRELLAHLYVLVPVLDDKKHYYVGDAEVENLLAKGEGWLAEHPEREAIALRYLKHSRPLFRAALARLVADEEASPEEAEDDKAAPEDRAEARMSLDEERRAAVVAALRRAEARSVLDLGCGEGKLLKRLVDERVFERVAGADVSMRSLEIAKNRLRLDDLPDKQRRRIQLFQASVTYRDARFSGYDAITLIEVIEHVDPPRLGALTRVLFEHARPRVAVVTTPNAEYNVRFEGLPRGALRHGDHRFEWTRAEFHAFCAEVAGAHGYAVEHLPIGPMDPSLGAPTQMAIFTRAAGEDGANGPGNADGHGGADGHGGADGGGAGAQAEEEAP
>NC_021658.1|WP_049949532.1|4730509_4731787_+|cellulose-binding-domain-containing-protein
MAYRTAAAFSLSGLFAVACTAEVPGEEAADDLTSAVVTTDGLGVAALTRSSDWGSGYCANVNVVNEGTTPVTSWTVVIDLRQSTLSNLWEAQSSRSGSLLTVTPASGRGQIPVGGAASFGFCATATGSDYQPVMVSMTQTGATGSGATTSSGGATGSGVTTGAGGSGGSGGGGGSGAGTTSGAGGSGGDGSGGTCAMPLPSYENGNGSATWYTLGSGSVNCSFPVLGSNPDRVAHVATGGGRYFAALNTADYDTAAACGACVEVSRDDGRKVVATVVDQCPTGSNPKCTAGHIDLSKDAFLQIGSAEEGYLGTGNGGARGKISWKFVSCPVEGNLSISLKEQNAWWNELRVQGHRNPIARVQVQLDGAWKEATRRDYNYWRLGDGNMKPGPWRVRVIDVFDEVIETTVQVTTAEQTASAQFSTCE
>NC_021658.1|WP_148314810.1|4732201_4733209_+|STAS-domain-containing-protein
MFVPSSVLGLMSGFQRMAGTERFNLAVESGGRLSVDDDWAFLSGYPTFEEGFRALGIGAATAGWGLWQVVAIDRARNEARFRVVNGWEALYQKELDVCWGSSMMAGKLAGYCTRLFGQECEVEQTSFAARGDPHDEFTVRPATTTLEERLNRLLDEERATKADLAIALHKLKREVEERARIAEELQKTEQELREKLSLIERQQRELRALATPIIQVWDGVLTLPLIGTLDGVRAGVITEELLDAIVRTGARFAILDMTGVDGIDEATADHVIRIVRAVELLGAKGVITGVRPAVAALITSLGLDMAAVATLRNVREGLRMCLRSLAGAPAGGGGR

Crispr_ID: NC_021658_16

• CRISPR_ID: NC_021658_16
• CRISPR_location: 4887622-4887739
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_16

Consensus_repeat	Method
GCATCCCGGGCGCCAGGCATCCCGGGCGCG	CRISPRCasFinder

spacers of NC_021658_16

>16.1|4887652|58|NC_021658|CRISPRCasFinder
CATCCCGGGCGCCAGGCATCCCGGGCGCGTCATCGCGGGCGTCATCAGCACGGGCGCG

CRISPR arrays and Neighbor proteins around NC_021658_16

CRISPR arrays

The CRISPR arrays of NC_021658_16

>merge|NC_021658|16|4887622-4887739|CRISPRCasFinder
GCATCCCGGGCGCCGGCATCCCGGGCGCCGCATCCCGGGCGCCAGGCATCCCGGGCGCGTCATCGCGGGCGTCATCAGCACGGGCGCGGGCATCCCGGGCGCCGGCATCCCGGGCGCG

>NC_021658|16|13|4887622-4887739|CRISPRCasFinder
GCATCCCGGGCGCCGGCATCCCGGGCGCCG	CATCCCGGGCGCCAGGCATCCCGGGCGCGTCATCGCGGGCGTCATCAGCACGGGCGCG
GGCATCCCGGGCGCCGGCATCCCGGGCGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020735410.1|4903140_4903956_+|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|369792
NC_021658.1|WP_044988363.1|4894651_4895383_+|SIR2-family-protein	unknown	unknown	gnl|CDD|379106
NC_021658.1|WP_020735399.1|4885126_4885852_-|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase	unknown	unknown	gnl|CDD|179108
NC_021658.1|WP_020735392.1|4877335_4877725_-|DUF423-domain-containing-protein	unknown	unknown	gnl|CDD|377259
NC_021658.1|WP_044985909.1|4879902_4882176_+|hypothetical-protein	unknown	unknown	gnl|CDD|225768
NC_021658.1|WP_020735393.1|4877828_4878374_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735398.1|4883391_4885089_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_021658.1|WP_020735409.1|4902064_4902949_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NC_021658.1|WP_044985911.1|4896113_4897151_+|aldo/keto-reductase	unknown	unknown	gnl|CDD|381317
NC_021658.1|WP_020735406.1|4895395_4895938_+|non-canonical-purine-NTP-pyrophosphatase	unknown	unknown	gnl|CDD|238285
NC_021658.1|WP_020735391.1|4873999_4877305_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NC_021658.1|WP_148314815.1|4897155_4897881_+|HAD-IB-family-phosphatase	unknown	unknown	gnl|CDD|226802
NC_021658.1|WP_020735397.1|4882745_4883402_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl|CDD|273139
NC_021658.1|WP_020735396.1|4882254_4882701_-|hypothetical-protein	unknown	unknown	gnl|CDD|240291
NC_021658.1|WP_044985912.1|4898709_4901226_+|penicillin-acylase-family-protein	unknown	unknown	gnl|CDD|376618
NC_021658.1|WP_044988360.1|4890353_4892534_+|response-regulator	unknown	unknown	gnl|CDD|236842
NC_021658.1|WP_187345969.1|4888830_4889961_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|335469
NC_021658.1|WP_148313645.1|4885950_4886955_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735394.1|4878370_4879657_-|EF-P-lysine-aminoacylase-GenX	unknown	unknown	gnl|CDD|273090
NC_021658.1|WP_020735404.1|4892829_4894290_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020735410.1|4903140_4903956_+|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.28964e-53
NC_021658.1|WP_044988363.1|4894651_4895383_+|SIR2-family-protein	gnl|CDD|379106	pfam13289, SIR2_2, SIR2-like domain. This family of proteins are related to the sirtuins.	1.40484e-30
NC_021658.1|WP_020735399.1|4885126_4885852_-|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase	gnl|CDD|179108	PRK00748, PRK00748, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Validated.	1.43848e-110
NC_021658.1|WP_044988360.1|4890353_4892534_+|response-regulator	gnl|CDD|236842	PRK11091, PRK11091, aerobic respiration control sensor protein ArcB; Provisional.	2.39079e-57
NC_021658.1|WP_020735392.1|4877335_4877725_-|DUF423-domain-containing-protein	gnl|CDD|377259	pfam04241, DUF423, Protein of unknown function (DUF423). This family of proteins with unknown function is a possible integral membrane protein from Caenorhabditis elegans. This family of proteins has GO references indicating the protein is involved in nematode larval development and is a positive regulator of growth rate.	1.75817e-18
NC_021658.1|WP_044985909.1|4879902_4882176_+|hypothetical-protein	gnl|CDD|225768	COG3227, LasB, Zinc metalloprotease (elastase) [Amino acid transport and metabolism].	1.37784e-11
NC_021658.1|WP_020735398.1|4883391_4885089_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	7.90606e-21
NC_021658.1|WP_020735409.1|4902064_4902949_+|serine/threonine-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.08755e-71
NC_021658.1|WP_044985911.1|4896113_4897151_+|aldo/keto-reductase	gnl|CDD|381317	cd19091, AKR_PsAKR, Polaromonas Sp. aldo-keto reductase and similar proteins. The prototype of this family is an uncharacterized aldo-keto reductase from Polaromonas sp.	0
NC_021658.1|WP_020735406.1|4895395_4895938_+|non-canonical-purine-NTP-pyrophosphatase	gnl|CDD|238285	cd00515, HAM1, NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides such as XTP to XMP and ITP to IMP, but not the standard nucleotides, in the presence of Mg or Mn ions. The enzyme exists as a homodimer. The HAM1 protein may be acting as an NTPase by hydrolyzing the HAP triphosphate.	2.42054e-30
NC_021658.1|WP_020735391.1|4873999_4877305_+|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_021658.1|WP_148314815.1|4897155_4897881_+|HAD-IB-family-phosphatase	gnl|CDD|226802	COG4359, COG4359, Uncharacterized conserved protein [Function unknown].	3.75855e-21
NC_021658.1|WP_020735397.1|4882745_4883402_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl|CDD|273139	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. Alternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis].	7.20935e-38
NC_021658.1|WP_020735396.1|4882254_4882701_-|hypothetical-protein	gnl|CDD|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	2.66449e-07
NC_021658.1|WP_044985912.1|4898709_4901226_+|penicillin-acylase-family-protein	gnl|CDD|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	1.61811e-120
NC_021658.1|WP_187345969.1|4888830_4889961_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	2.21423e-20
NC_021658.1|WP_020735394.1|4878370_4879657_-|EF-P-lysine-aminoacylase-GenX	gnl|CDD|273090	TIGR00462, genX, EF-P lysine aminoacylase GenX. Many Gram-negative bacteria have a protein closely homologous to the C-terminal region of lysyl-tRNA synthetase (LysS). Multiple sequence alignment of these proteins with the homologous regions of collected LysS proteins shows that these proteins form a distinct set rather than just similar truncations of LysS. The protein is termed GenX after its designation in E. coli. Interestingly, genX often is located near a homolog of lysine-2,3-aminomutase. Its function is unknown. [Unknown function, General].	1.1792e-121
NC_021658.1|WP_020735404.1|4892829_4894290_+|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	3.1337e-43

Protein sequences

>NC_021658.1|WP_148313645.1|4885950_4886955_-|hypothetical-protein
MRQTMTRCLRRIAPLALVLCSLAAAAPAAAQDSAAAEALFNQGLADMEAGRYEAGCKAIAESHRIEPKLGALFTLATCESRWGRIAAASAHFGEYLAQYEQLPPEQKSRQGDRPKVARQERDRLAPLVPELSLALPPGAPTGTVVKRDGDVVDGAALGASVPVEPGEHVVSTQAPGGSVWETRIQLAQGEKKRVELQVNGAGAAPAGGASGRRTAVYVAGGVGVAGLVLGGITGALTLGRKSIVEKHCGSGIGSSDETACDQIGLDAAESASATGLVSTIGFGVGLAGLGAAAVLYLTEPKQSDATAGATSSRIRAGVLAAGPEGVVLGARGAW
>NC_021658.1|WP_020735399.1|4885126_4885852_-|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase
MQLIPAIDLLGGQAVRLHQGRYDQVTVYDQDPAALAARLRRSCDRLHVVDLEGARAGRPVQADAVRAVVAAFGVDGGSVQVGGGIRSAAAAESYLALGAERIVLGTAAVNDPALVRDLAGRFPGRVVVAVDAKDGRVAVQGWEQVSSVTALDVARALAGAPIAALLYTDVSRDGTQVGPNLEATRELAGSCGFPVLASGGVGSLSHLRALAQIPGVSGVIVGRALYEGAFTLAEAIEAASA
>NC_021658.1|WP_020735398.1|4883391_4885089_-|tetratricopeptide-repeat-protein
MPERDDPRPSTREVAAEEFLFHLHRGSELLQDNRVHAAKAELERALSLQPSDPKGQDLLGIVYFRLGLYPRAIAIYERLIQAHPEAVEPRINLALSYLKTGQPAQARSELEKALDQNPKHQRAWGYLGLAFQRMGDYERASHAFAAGGHDAMARRLLDMTGGSTGRYPAEPPDTEDQPPVEARAEARAEVQRAAGEAVQALDRAGAGFRHDSDLPRIPSGTWSAIEPGRETMPTIPAPPSLRSLGADGRGGGAAGAAMPSRSPAPRGGAAPTVPSMAAVQAPPGGGAAPAVRRGSMAPEEPSMTGRFTVPVAAAGDAALAGRKAAARSSSSSLPPPTAAPGTPPPSTTPLAVQPPEALLSVARERLLVFPRDVAVARHASGVVLVQAAKGFVARLDALRTMSTLPGTATHVLKRQARGRVFDEPLGGPSTPFVEIGARCELVLGALEGRRLHAVTLGEEPIFLREDVLVGFELPIGYENGRLPAGDGEAVAMVQLRGRGHMVLSVPERAAALEIAPSRPTSMRATAVLGWMGRLLPRTLPATEAPGGLQGFVTFGGEGMVLVDGR
>NC_021658.1|WP_020735397.1|4882745_4883402_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MVASAETSLRGIKAQRRRTLWEDAKNLPNLLTFARVLMIPAVLLLLSRGAPRDCFWAACVYSLAAITDMLDGYLARRQGLVSVLGKFLDPLADKLIVAATLVWLVPMGRIPAWAVVLLISREITITALRSIASTEGLVIAAGDGGKIKTALQMIGIVCLILGYPYRIHLGVDFGEVDVVHVGRLLIYLSLVFSITSAAQYMGLFIDAIDAKNRAAPPP
>NC_021658.1|WP_020735396.1|4882254_4882701_-|hypothetical-protein
MKALKTSRNALRPALLLAALAAAFVASAASCSQQQEGEPCEIANGNDDCASGLECRGIGQQQQQHRCCRPGVVTQVCDPTQNPVTSTTTTTSGTGGAGTGGSGGDGGTAGDGGNGGAGTGGAGGNGGAGGAGGAGTGGSGGAGGDGRR
>NC_021658.1|WP_044985909.1|4879902_4882176_+|hypothetical-protein
MGRQLLLLPLTALATLTFAGAAAASEWHTVPPSSVSADPSLRVAGGARSAAEAYLKRAVSELRLQGVSLRYERELQDGDHRTVRFAQFHAGLPVLGGAAAVHVAPGARVELVVLDVARDLSVPAAPKYREEAARSAVEATYGMSLPERPSAALAVFPEAETGGKLVWVVDVRSELGGERFLVDAHAGKIVHRRSLAVHARGRVYPISSAVTPRLEDRDLVDLDAGDPQTLSGWGGNLRVVNYVDGDLMSGVPLTLEQRVGPNAGEDFLYDPPRSADDARDEFAQVGVYYHLTRMRDYFTTTHQLDMASPSWKLVAIANMLESGRPMDNAFFSPMGSEAPFSAPNLIAIGQGSFFDFSDDSDVFLHEFTHYVTANAVGYSEGQFAVSAYGLSPWAGSIDEGLADYFACTVNGDSTLGEASLEPFGAQRELSEDVKVCPDDLVGEVHDDGELIGSLAWSLHEKFGAELGDKLVWSALTLLTRNASLGDFAKALTRATDKLVGSGELAAEDADTVAALLKSRGLDDCEEVLDLSGGKSRRTHMFGIDSLVYGTGASCVEWRRQLSLQSLFHFKSTPDRTAKGIRFTVELEPRGGSDLDWSIYVRSGRHVGFAMGDVMPEARNYDYSVEGITDTYGEIVIDETSDPPFDPTQTYYMVIGHANCPSTAVSVDSADLGVEPPPVDPVDPVEPEPGSTGGATPEPTDPAEETPAEPPAAGCACRAAAPSAPVAPWTALAGIALAAAAALRRGARRNRLERREPR
>NC_021658.1|WP_020735394.1|4878370_4879657_-|EF-P-lysine-aminoacylase-GenX
MTLLHTDVSTGAPATLAPSDIASAGATLPGRVRVGGRVLEVAEGAFVLGDAFGALRVALEGAPAPPVEIGDLAVVEGAPAGGALASARLVERIAPRRPPRGRSGAAAPPSSETERAIHRGLGLALARRAAALAAVRALFAERGFLEVETPSMVPSPGLDLHLDAFAVEAARPTFLITSPEYQMKRLLSGGVPRCFQLARCFRRGELGDRHNPEFTMLEWYRAFAGVDEVMSDTEAIVQRVAGALGADGAISVSGKAVRLTPPFPRISVGDAFARWAGVPADDAIALASSDEERFFRLLVDAVEPAIAALPHPVFLVDFPAPFASLARLKPGDPRVCERFELYVAGVELCNGFGELTDPVEQRARLLADQAARAARGKPVYPIDERFLGALEEGMPPAAGNALGVDRLVALCLGATSIGDVLAFPHGWL
>NC_021658.1|WP_020735393.1|4877828_4878374_-|hypothetical-protein
MTAVPEGGARLSPDILAQLARKYRTLAALRRARAAGEAIPGKEVFRALAGEFPGALNELDNLPLDEIDRRHDALSRALAGGAEERWMAWMHGYHALMRAALYVKIRVARRQELSEGEAAALAERAARHAGAPVDAAFVLAVKAPPDGRLNRVVLGRLAAMSGASMAEIRGTIFPRRPAQGG
>NC_021658.1|WP_020735392.1|4877335_4877725_-|DUF423-domain-containing-protein
MERLFFLLSGVYGFLGVALGAFGAHGIKAKLDALPDGALRASWWQTGSLYHLVHALALALAAHLAARTGGTAATAAGFCFAAGVLLFSGSLYVMTLTDLRLGAVTPLGGLFFLAGWGAVIVAALGLAKG
>NC_021658.1|WP_020735391.1|4873999_4877305_+|efflux-RND-transporter-permease-subunit
MQALARICIQRPVFAAMLGLALIVVGAVAYFRLGVDRFPAVDLPTVSVRTTLPGGAPEDVEAEITEEIEEAVNTVEGITELRSISSSGSSVVIATFNLDRDVDSAAQDVRDRVQAALRRLPVGTDPPVIAKQDNDSTPVMTIALSADRSIRELTEIADKLVRVQLERSAGVGEVRVVGGQERAIKIWLSADRLAAYGLPITAVREAIVQQNANIPAGNITGKEEERTLRTMGRLEHAGDFNNLVVGNVDGRPIRVRDIGRAEDGTYEQRSLARLDGRPTVVLDVVRQSGANTVAVIEAVKANVAKLSDQLPSDVKLEVIRDQSGYIYTALHEINVHLVLGSFLACAVVLLFMRSWRSTIIAGVAIPTSVVATFGMMWALDFTLNSVTMLALVLMVGIVIDDAIVVLENIFRFVEEKKMDSFEAARAATQEIGLAVLATTLSLVVIFVPVSFMSSISGRFLFQFGITATVAILVSLLVSFSLTPMMSARLLRKEASRAHGSADAGGGGEAATRTGFYGRLEAKYMGALAFAMRHRALVATFAVLVTASAVPLYGLVKQEYIPSGADDAEFEIRVSAPLNASIGAMDDVMRRISDDVRSVRGVRSVLATAGGGFIGGVSSGEAFVRIAPHDERTFSLTRLFRETFSGNPLRAFKDNYAQSEVMQEVRRKLRKYTDLRISVRNVPSFNIGGGNFEIDFAIQGPDIAALERYANELRDRSAQLGGIVDADVTLKIDRPELRVIIDRERAAALGVRTEDIASALRLMVGGDQEVSRFRDEEANENYDVQLRLVEGDRDQLAAVRRLYVPRTARPQAGSAGAAAAPAAGAPLLRGDLVRLDNLVRIEEAKSPSRIDRLDRQRVSSLRAGVAPGYALADRLEALRGAAREMDMPSAYTTSVRGRGAELERTFGEFIWAFLLSIVLMYMILASQFESLVHPVTILLSLPLSVPFALLSLWATGNTLNLYSALGFLVLFGVVKKNSILQVDHMNKLRAEGMPRAEAILHANRDRLRPILMTTLALVAGMLPLWLGTGPGAEERHTIAVVVIGGQSLSLLLTLIVTPVSYSLLDDLAHSERWGRVRARIGAFGERTSARLGRLFARARRST
>NC_021658.1|WP_187345969.1|4888830_4889961_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MSRSAVAMWTASCLAMGGCTAIVGVDEPYHLADGGGGAAGGGGGGGGGGEPCTPHEVRCREDRPQTCDENGRWQDEAECPEEAPLCRDGGCTVPRSCADMDAICGPRGDESCCASLLVPGGTFDRGDAEPRLATVSDLRLDRFEVTVGRFRAFVSEYPAAWPVVGAGAHPKIPDSGWRAEWDDKMPVDRDALMAWTHCEDPYHSWTDEVGDHELLPVTCVSWFVAFAFCAWDGGRLPTAAERHYAAAGGDEQRQYPWSTADSAAEPDESYAVYGCGLDGSCEIADLQPGGSRSPRGDGRWGHADLGGSVWEWVLDSFAEDLPLECEDCTVLTPDANHMIWGGGWRSEEETLLTSAFEERSPGGEFAGTGFRCARAP
>NC_021658.1|WP_044988360.1|4890353_4892534_+|response-regulator
MDVNGPEGARPETLLIVDDVPANLAVILAHLEDQGFEIAIAQDGEEALERAELLRPDLILLDVVLVPGIDGFETCRRLKASASTREIPVIFMTALADTADKVAGFEAGGVDYVTKPFQLDEVVARVRTHLAMHAMRRKIAAQNAQLQREIAMREQFESALRLAHGALEQRVAERTVELAAANATLQEESAERKRALAALSESQRLLRAVIDNSTAVIYVKDAAGRYVLINRHFERLFHVTEASILGRTDDELFPPAQASAFRAHDRRVLDARTPLQAEELVMQDDGPHTYISIKCPLRDAADEPWAVCGISTDITERKRAEEEREALLAREQAAREKAEAADRLKDEFLATLSHELRTPLTSIVGWAQLLCTGTLDAATMRRGLESIARNSLAELQIVEDLLDVSAIVSGKMTLKAQPVCLASVLRAALDTLTLAADAKGVSVSLSLNPEAGKVWGDGGRLQQVVWNLLGNAVKFTPPGGRVAVSLDRVGATAQIRVSDTGEGISAEFLPLVFERFRQADSSIQRRRGGLGLGLSIVRRLVELHGGAVRAESGGPGQGATFTVDLPLLPSVEAPAAPGAALAPRGSGAAPPPVLAGLRVLVIDDAPDMRELMARLLSGAGAEVRVAGLAREGFELVEPWRPDVIVSDIGLPGEDGHALIRRVRALPAERGGATPAIALTAYAGQSARDRTLSEGYQMHLPKPVDPAALVEVIARLAHPGGPELSRT
>NC_021658.1|WP_020735404.1|4892829_4894290_+|STAS-domain-containing-protein
MQDDLSRETEEKPVTVKSVGTTHTLEPDLGRFRWECDRGMLFTHGRPSVLFWLNPSLYRMLEPLVNEVGVPLFRLMVAQHSSMGTAEDYDTMVTALGETFEEGFLAWGSAVGMGGWGRFELPVFDEESRRAVVVVRNPWELEMQRGSTVRWGCPFLQGKIIGILSHALGVNCWADELLSAPDEAQASVEFRVYPSDRTLDAEMTRLRLAHHEEAKRKLEERTLELRQSEAQQRAILASLSEVVFTLDEGGRLTSYHVPKEVGAFHEAPERAIGRHVRDVMPQRIAAVLLDAIADLARDGAPRAVSYAREHGGEERFFSAKLSILRDPVSGRGGVTVVERDVTDRVRAEHALTERLNVIERQQEMIQVLSTPIIQVWDGVLALPLVGVIDGRRAASITESLLREIVSTQARVAILDLTGVDVVDSAIADHFLRIVRAVELLGTTCLISGIRPAVAQTMTQLGTGIEKARTFGTMRAALMSVTRRQRA
>NC_021658.1|WP_044988363.1|4894651_4895383_+|SIR2-family-protein
MWRELMGWMGQALGFEPALFELHGLPPQLAGFFARECDGGLDSFIAEMRARFHAREVNERRRSSRQHKALARRHFRTIYTTNFEHHIEEALRDAGKEAVALSTFDDFARCPAQGACHVIKFHGDLNWPETVVLTEAQYFGRLRLEAAPDQRLRADLLSNTFLFLGYSFGDVDIRYIWYRMEQMRLEGSAPGAKRALNRRGYWATFGAGLVQPALLEDWHIDVIELDPNDKTKSVVDLLDALDG
>NC_021658.1|WP_020735406.1|4895395_4895938_+|non-canonical-purine-NTP-pyrophosphatase
MVYFVSSNEDKLEDMIHAWKDGPTPLRVLRLDVPEVLSSDLDVVVREKALAAYRLALVPLFVEHGGLFIEHLNGFPGPLVKPFWERLQDRICSLIPPGMSRAARVVQKVCYCDGRTLRIYTGSVLGEIACERRGDEGIHWEPMFIPAGHARTLGQMHREERLRCSARTEALRAFRSDIDL
>NC_021658.1|WP_044985911.1|4896113_4897151_+|aldo/keto-reductase
MEFRLLGGSGFKVPVLSLGTGTFGGGNEFFRGWGATDVAEATRLVDVSLEAGMNMFDSADVYSNGLAEEILGQAIKGRRDRVIISTKATFRFGPGPNDVGSSRHHLLRSVEGSLRRLQTDYIDLFQLHAFDALTPIEETLGALDDLVRAGKIRYLGCSNFSGWHLMKSLAVSEKYGLSRYVAHQAYYSLVGRDYEWELMPLALDQKVGAVVWSPLGWGRLTGKIRRGQPLPEVSRLRNKLAAEGGPQVDEEYLYRVVDALDEVAKETGKTVPQIAINWLLQRPSVANVIIGARNEEQLRQNLGAVGWTLAPEQTARLDAASKTPLAYPYFHQTGFAERNPFPVAV
>NC_021658.1|WP_148314815.1|4897155_4897881_+|HAD-IB-family-phosphatase
MRWRPARRRAQSAAVLILSDFDGTITCADLTNEVWDAHLRYDWRKELLTLSASGQITPFELLRRGYADVDRPEDELLALLRPHAGLRPGFDELLALCARRGWVFHVVSHGLPFYIREFLPPGTAFSCFDAVFDGRWRVTVPEAVRLGPGDDFKIRVLDELKAATGEAATVYIGDGRLDYPAARCCDRVFAVRGSALDVLCARDGVPCTPFDSFTEVCAALDLGGERPAGAARAGERAPGRG
>NC_021658.1|WP_044985912.1|4898709_4901226_+|penicillin-acylase-family-protein
MTGVAFLLSAAACSVAQDDQGLAEQTAAKETAVEISGLDVAYIRVDDRGMSHVTAWDEKAGYGGLCYAMARDRLFQMDVLRRSAEGRLAEIYGPGDDDAILGQDLLARAQNLRAFAAARYATAASRTKRALQGCAAGVNKYISEAKASSGGLPLEFQTLGYEPDPWTPEDSVLAYIYVGVTFDTLTWFTKLERAAVASIAGTEVATTLIKEAPSEVSMFDAQGNLNPISTFLVPPGPTTPSATIVNPPPPTCLEGARRLTEQLRQMTPVSGRASNAWAVDGHLTSTGKPLLATDPHFPHATPSAVYLAQLKVNGQYNVAGWMVPGFPGFISGHTESIAWVPTFSLFDSVDLYVETLRPASGGKQEVLINGQWKPVTKRVETLRVKGQPDVQRTFRSTPHGPILNDGLDGLEAFGTLALKSTAGQPEWKVDGYFEMPAAQSFPQFKAAALKQSIGWNFIFADYAGTHGHIGYQNSGLAPQRQSPLNALYPVPGTGGHEWTGYATNAELPSVYDPPSHVLVTANNRMVPRDYAPQGRPVHLANYWDMPWRAQRIMTRLTTATQPLTPQDMASIQLDTQTTIGLPLRDSYLAALGRVGLPAGDPSAVAAVEALQQWDGNAAASSRGAAVYEMLTLILLRNTVTDVIGPDEYALFAPNVFLTNQLNGLIDVLENPRAPYFGISEGVDPGVARDEAVRRALGEADAMLRGALGSDVSAWTWGGIHELTYNHPLAGEDARFDIGTFPATGDVETVNIGGWFAKVGILALPPGEFEAAGGVRGALDQDSLSATRLVWNLAPLDGSLGVMSTGISGDPRTCHYADHAEAWRAGQIFPMPFTSAAIP
>NC_021658.1|WP_020735409.1|4902064_4902949_+|serine/threonine-protein-phosphatase
MTEATLGAGDITVKACGITDLGRVRKNNEDTLLIAHLTSAAKTAPPAHEVTFEASYPVLLAVSDGMGGAAAGEVASALVVEALRRAMASARGNWDDATLQAVQRANREVWQAAQQPGRHGMGATLTAICVHGTEAHVAEVGDSRAYLIRNGQILQITHDQSFVQALIDAGMIQPEEAEQHPMRSMLLQAMGLDPDVKASVARLDLRRDDRLLLCSDGLSNKLSAEDMLAVIERGPSIEAACERLVALANDRGGEDNITAIVAELHGGGLTPPRRGEKPTQTLHTVTEFDPRKKA
>NC_021658.1|WP_020735410.1|4903140_4903956_+|Cof-type-HAD-IIB-family-hydrolase
MVPGSFRGVAFDLDGTLLRSDHSISPEMRSLCSALTGRGLLVTLISSRPPRSVEQIAASLGLSGPWAALNGAFVVGSGGESLGRSPLPEATVEHILARYGRDERISLNLYAGFDWIVQAADRRVRAEADIVGFAPIVDVGFASRPATEKLLMITDEGSRENARLTEELAALDDGIAVARSKDNYIEITRREIDKGRALALIASSRGLSAREMVAAGDGENDIPMLKACGLPIAMGHGPQPLKQAAALIVGSNDDGSLTDAIGRIFGAAPAR

Crispr_ID: NC_021658_17

• CRISPR_ID: NC_021658_17
• CRISPR_location: 5329135-5329478
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of NC_021658_17

Consensus_repeat	Method
CGCGNGAAGGGCAGGGCNTTGTCGGC	CRT

spacers of NC_021658_17

>17.1|5329161|19|NC_021658|CRT
CGGAGGCGAGGAGGCAGGG
>17.2|5329206|19|NC_021658|CRT
CGGGGGCGGAGGGGCAGGG
>17.3|5329251|19|NC_021658|CRT
CGGGGGTGAAGGCGCGGAG
>17.4|5329296|19|NC_021658|CRT
CGGGGGTGAAGGCGCGGAT
>17.5|5329341|22|NC_021658|CRT
GGTCGGAGCGATAGGGCCCGTC
>17.6|5329389|19|NC_021658|CRT
TGGAGGCGGAGGGCTGGGG
>17.7|5329434|19|NC_021658|CRT
CGGAGCGACAGGGGCCGAG

CRISPR arrays and Neighbor proteins around NC_021658_17

CRISPR arrays

The CRISPR arrays of NC_021658_17

>merge|NC_021658|17|5329135-5329478|CRT
CGCGTGAAGGGAAGCGCGCTGTCGGCCGGAGGCGAGGAGGCAGGGCGCGCGAAGGGCAGGGCCTTGTCGGCCGGGGGCGGAGGGGCAGGGCGAGAGAAGGGCAGGGCGTTGTCGGCCGGGGGTGAAGGCGCGGAGCGCGAGAAGGGCAGGGCGTTGTCGGCCGGGGGTGAAGGCGCGGATCGCGAGAAGGGCAGGGGGGCCTTGTCGGTCGGAGCGATAGGGCCCGTCCGCGCGAAGGGCAGGGCGTTGTCGGCTGGAGGCGGAGGGCTGGGGCGCGAGAAGGGCAGGGCCTTGTCGGTCGGAGCGACAGGGGCCGAGCGAGCGAAGGGCAAGGCCTTGTCGGC

>NC_021658|17|5|5329135-5329478|CRT
CGCGTGAAGGGAAGCGCGCTGTCGGC	CGGAGGCGAGGAGGCAGGG
CGCGCGAAGGGCAGGGCCTTGTCGGC	CGGGGGCGGAGGGGCAGGG
CGAGAGAAGGGCAGGGCGTTGTCGGC	CGGGGGTGAAGGCGCGGAG
CGCGAGAAGGGCAGGGCGTTGTCGGC	CGGGGGTGAAGGCGCGGAT
CGCGAGAAGGGCAGGGGGGCCTTGTC	GGTCGGAGCGATAGGGCCCGTC
CGCGCGAAGGGCAGGGCGTTGTCGGC	TGGAGGCGGAGGGCTGGGG
CGCGAGAAGGGCAGGGCCTTGTCGGT	CGGAGCGACAGGGGCCGAG
CGAGCGAAGGGCAAGGCCTTGTCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020735716.1|5348786_5351489_+|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl|CDD|235444
NC_021658.1|WP_020735708.1|5330281_5330716_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735704.1|5321014_5323771_+|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl|CDD|274542
NC_021658.1|WP_148314826.1|5318763_5320998_+|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl|CDD|274542
NC_021658.1|WP_148314827.1|5342016_5342988_-|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|223704
NC_021658.1|WP_148313689.1|5314388_5316041_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734339.1|5328391_5328688_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044985956.1|5340523_5341576_-|hypothetical-protein	unknown	unknown	gnl|CDD|366517
NC_021658.1|WP_020735699.1|5313630_5314128_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020735713.1|5336115_5340243_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020735710.1|5332766_5334326_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NC_021658.1|WP_044985954.1|5316462_5318697_+|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl|CDD|274542
NC_021658.1|WP_020735705.1|5323770_5324358_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NC_021658.1|WP_044985957.1|5345767_5348656_+|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NC_021658.1|WP_187345980.1|5324802_5326116_+|neprosin-family-prolyl-endopeptidase	unknown	unknown	gnl|CDD|367323
NC_021658.1|WP_148313694.1|5344037_5345771_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020734338.1|5327305_5328373_+|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_021658.1|WP_044985953.1|5312611_5313466_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
NC_021658.1|WP_020735709.1|5331513_5332839_+|hypothetical-protein	unknown	unknown	gnl|CDD|131323
NC_021658.1|WP_063751998.1|5335344_5336082_-|OmpH-family-outer-membrane-protein	unknown	unknown	gnl|CDD|214922

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020735704.1|5321014_5323771_+|type-VI-secretion-system-tip-protein-VgrG	gnl|CDD|274542	TIGR03361, VI_Rhs_Vgr, type VI secretion system Vgr family protein. Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.	0
NC_021658.1|WP_148314826.1|5318763_5320998_+|type-VI-secretion-system-tip-protein-VgrG	gnl|CDD|274542	TIGR03361, VI_Rhs_Vgr, type VI secretion system Vgr family protein. Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.	2.02767e-161
NC_021658.1|WP_148314827.1|5342016_5342988_-|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	9.72405e-68
NC_021658.1|WP_020735713.1|5336115_5340243_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.45499e-76
NC_021658.1|WP_044985956.1|5340523_5341576_-|hypothetical-protein	gnl|CDD|366517	pfam01213, CAP_N, Adenylate cyclase associated (CAP) N terminal.	8.15183e-06
NC_021658.1|WP_020735716.1|5348786_5351489_+|DNA-mismatch-repair-protein-MutS	gnl|CDD|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NC_021658.1|WP_020735710.1|5332766_5334326_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000190879
NC_021658.1|WP_044985954.1|5316462_5318697_+|type-VI-secretion-system-tip-protein-VgrG	gnl|CDD|274542	TIGR03361, VI_Rhs_Vgr, type VI secretion system Vgr family protein. Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.	1.31837e-167
NC_021658.1|WP_020735705.1|5323770_5324358_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.00673128
NC_021658.1|WP_044985957.1|5345767_5348656_+|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.000304041
NC_021658.1|WP_187345980.1|5324802_5326116_+|neprosin-family-prolyl-endopeptidase	gnl|CDD|367323	pfam03080, Neprosin, Neprosin. Pitcher plants are insectivorous and secrete a digestive fluid into the pitcher. This fluid contains a mixture of enzymes including peptidases. One of these is neprosin, characterized from the pitcher plant Nepenthes ventrata. This peptidase is of unknown catalytic type and is unaffected by standard peptidase inhibitors. Unusually, activity is directed towards prolyl bonds, but unlike most peptidase that cleave after proline, there is no restriction on sequence length or position of the proline residue. The peptidase is secreted and is presumed to possess an N-terminal activation peptide. The neprosin domain corresponds to the mature peptidase. It is not known if other proteins with this domain are peptidases.	4.38973e-28
NC_021658.1|WP_020734338.1|5327305_5328373_+|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.29718e-21
NC_021658.1|WP_044985953.1|5312611_5313466_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.54169e-20
NC_021658.1|WP_020735709.1|5331513_5332839_+|hypothetical-protein	gnl|CDD|131323	TIGR02270, hypothetical_protein_GSU3180, conserved hypothetical protein. Members are found in Myxococcus xanthus (six members), Geobacter sulfurreducens, and Pseudomonas aeruginosa; a short protein homologous to the N-terminal region is found in Mesorhizobium loti. All sequence are from Proteobacteria. The function is unknown. [Hypothetical proteins, Conserved].	7.62826e-14
NC_021658.1|WP_063751998.1|5335344_5336082_-|OmpH-family-outer-membrane-protein	gnl|CDD|214922	smart00935, OmpH, Outer membrane protein (OmpH-like). This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.	1.36696e-24

Protein sequences

>NC_021658.1|WP_020734339.1|5328391_5328688_+|hypothetical-protein
MAKLHADPVHAEAVASRLSARGFPHLRARKRGELVVIESGPDDDPIPHARLRRDTVQLWRLEIATHTGRWEPTGIRAPLKDILDVLVHDFPWVLTPVV
>NC_021658.1|WP_020734338.1|5327305_5328373_+|IS630-family-transposase
MPPKVRKRLARYARSSKLPHRIVMRAKIALLAEQGLSNAAIAEQVGCDVKTVRKWRDRMAALEDPLALEDDYRKGRPARISLEVHHELIKLACQRPTDDKSPFEQVWTLKTLAEALAGSTGVRMSRTEVWRILEGASLKPHRVRLWLHSPDPDFRPKVAKICSLYVQPPEGATVLCIDEKPGMQAREQRFAPRACGPGRPGRKEFEYRRRGTRTLIASFNIRTGEVLAACGPTRKAHDLLAFMERVAEHYPTGPVYIVWDNLNIHSGPRWAEFNARHGGRFHFVHTPLHASWVNQVEVWFSILTRRVLRHAAFRSVHELTARVLAFVEHWNRVEARPFRWTFRGRFRRTLHPRAA
>NC_021658.1|WP_187345980.1|5324802_5326116_+|neprosin-family-prolyl-endopeptidase
MRADSRVYLPLLIASLLSGCAGTDDDGSAPPEGIGVAELEASSRLPEPAVRRVDPPQLTPEQQRRQAEVDQLLAERYRGYKIVETTQAYSGDIIDWVDSDTIPGARLAPPPPPWSEKDLRPASGAQLARTELEAYPELRGPKGTTPIHRPDFSVYVMGETDAQSLQDYIENYQVSGQPAGQNRLYAGLITTAANKAIAGVINQFQGDVETGTLTLIEAATLCRGWNEPTTLEMVGAVVSRDRANFGNSQTRIQVEFFTHGPTTFGNNVGGWDTFVTGFVPAAGRPYGPNSVVLASTPGLATQQESRFDISQDSSSNWWVAHNGNWLGYYPASLFNLLSISACEAAWYGEVYDPTPTDWTWTDMGSGQFDTAGYAFASYVRNPTYLDLLGVGWYPGVHFAMGPVDAACYTRSALTTGATPWDRFFYLGGPGGNAVGCN
>NC_021658.1|WP_020735705.1|5323770_5324358_+|hypothetical-protein
MAASFDGDPGRSGAPAAVEELEPGGASGAPRVTLDDVLAEPAAEAAAPAEAAAPLPALGAQPLGVAMRTARVAAVAGRQARIVVRGAAGEVEALVAPEVDPDVIADAHARGDAVLVELCEGELPLIVGALTTQRPKALHLKAATITLEGEQELLLRSGRGAVRIREDGDIEVVGSRISAASRGLFRIVGRLLRLN
>NC_021658.1|WP_020735704.1|5321014_5323771_+|type-VI-secretion-system-tip-protein-VgrG
MARETIAHFTIDEVPAARVLRFESIHEAGRPLVVDVEVILHVFQELDAMIGKPAALSFGAPGEPPRVLAGTVEAATSIGTTELGMEAIGARYAVRVVSSLALLARSVDSRIFQDMSAKEIVAQVLEEHGVARVEWRLSGDCPKREYCVQYQESALAFISRLMEHEGIYSFVEVDADRELLVFDDDSTIAAPIPGDPALPFRRRTGLSAADERDAIYALRELERVRSGKFVLRDFDFERPALDLTASAASSEHAELERYDYPGGYVEPSEGQRLAQIRLEEEQVERRTIEIEAVCPRLAVGHTLTLTDAGELDGEYFLFAVTHTFVHDDGEEREGAASRSRARARLVPADVKYRPRRVTPIPVIEGPQTATVVAPAGAQPEAIHTDEHGRCKVKFHWDRSDVTDDKASCWMRVAQLQTSGSMMLPRIGWEMIVEFLEGNPDRPIVTGRLYNGVYMPPYALPEGKTRTAIRTASTPGGGGANEVRFEDKAGAEEIMVHAQHDMKTAAANNAKKNIGNNETTVVGNNASLEVGGNQTTKITKGSSNTVGADQTIGVGGNRTLEVNAVSAVTAKGNATTTVGGNQFEMDGNPLEAMLALAAQAAVQFASVMANNAISAIQGQVDGAINQVMGPINALTQQAQGVAGAMRAVAGGDMGRMPAMIAGASGIPGASQLAASMGGGGGGGGGGGAPGGSGPPNMLASIASNAVHSSLAGRVFVQPEALASALGMDAAGGGGESMANAAGPEGNVDGVDATDREKGPGHSTAKVAGTHKEDVGSMKILGAIQDIDNNVTGKKTIDVGAATVQVAFGSYAESVTGSKSEKATGLVVLSNAGESETITGSRTAMVGGAVVDKLKGSHVVQAVGPATFIGAFHKVEAKGAIVFKCGASEVVIDGGGVTISSPLVALLAPKIQLPKKVSEV
>NC_021658.1|WP_148314826.1|5318763_5320998_+|type-VI-secretion-system-tip-protein-VgrG
MEGKVYRVLRFELSEQLSELTHLECELLDDAAALPRPKEVLGKRAVFTLSRSDDTQTRAFAGTIVLAELLPDPDDVPTLRIQVAPALWNLAQRADCRIFQDKSAVDIVKEVLEGAGVPAGQQEWRVTEPHPARVYTVQYRERDLDFVHRLLAEEGIYFAIHTRGEQDVAVFSDAPNGLEDIEGATSLPFFQDFGVAGSADRVARLSREVSVRSDKVFVRDYNPEKPSLKLEASAESSDPGEHALEIYEYPARTADVGVAERLAKVLLDAVQAERDVVRGETGSLALLPGRRFSVEGHPYDPLNQEYLVVRSRIAGSRPRNFELSGRDAALEGARDVRMACEFWGVPTGTTRYRPPRRAREQVIPGAQTAITTGPSGQEIHTDASGQVKVSFHWDRSGKKDDTSSRWIRTSQVPTGGSMLLPRVGWEVTVRHVEGDADRPFVMGRMYNALTPPPYALPKEAGKSSLQTATTPGGGSSNELRMSDTKGGEEMFMNASKDMSTEVKNNATESIGNNHAKKIGADQTTNVTNSMTSSVGANQKISVAGNQAMKVETFHVDDIGGDHSLSIGGNRDMKIGGDHKRDVAGDSALNVSGNQIDLVVGSVTDQTLAGFDHEVGAALVELALGHRSVTVQGDRSETATGAKVIAVKAGRGVQVGGSMNVKVGGAIVNVANGDRVESSLGTYTELAGGAQLVKANNVVFEATGALTLVMGASIVSLTPASVAILGVSAKLDGDVADTAALVIDN
>NC_021658.1|WP_044985954.1|5316462_5318697_+|type-VI-secretion-system-tip-protein-VgrG
MAPMADTFATFSLEGDKLPADTAVTRFEAVEAISTPYTVEVRFATLDAAFRVEDCLRSRLCLRVTDTSGKERLFDGIVDRAGFARIAGDSRQFDVRLRPALAALAHREGCRIFQEKTIVQVAQTIFEEAGFGDKVEWRTAKEYEPREFIVQYRESHLNFVSRLLEDNGLFYYFRHDAAGHTMIITDDPAAFAVEEGTPVLFRMAQGGIPGSLPLNKLTRTRALRTSSVHLRDYDFEKPDVKPESSLPRKEAFVLPYFEYPAGFTKGSVGARRADARMRELAADADVCEGESRAAGLKVGEPFLVEGAAEPCLNGEFVVTHLVSRGNQTLTGGDTNVDVENHFRGIPKGAPFAAERRARRPRIRGVQTAVVTGSSTQEQAIHVDKYGRIKVRFFWDRQGQQDHTSSCWLRVSQIAMGGSMILPRVGWEVSVAFLDGDPDRPVALGRTYNAEKTPPQALPASKASGSLKSMSSPGAGGHNEIGMSDSSGSQGFGIHAQKDLNVTIGNDKVEEVAVNEEQHISVNGSRSVKVDESISVAGNQSLDVGAVLSHKISGNQSISIGGNDTTNAISNYVEKITGNRSYTVSGNQITISNGIEQSITGDMSRKVGALQLSGSLASINDNVLGGMTETVGAVKAQIINGSHGEQITANKDQTSLAAELHLTKGSLSHVAAGVTNLVGGLHYQKLNGDLVVQAPLITLLGAVGVFKGGGSELKLGGGPIVIKGSKIAVKGALVVKMGASMKLGS
>NC_021658.1|WP_148313689.1|5314388_5316041_+|hypothetical-protein
MGNIIKMHLRAPIFLTLLLVTGCGSNASINTSAQKTLKASPANCEIAVQLLDARAPKKVTFMSEPACMQAKGSALTFPTTMTLHYKERLGPPYDRDLCADEAVGPETTKGDKLYSCQWNGTFRDRHPMTFRIFSAHTPAANDAPLDIGTRIQLIHVFRNGKLVFKWLPPALPVTEVLIHGSAIEGEGIPHLAPLDVRVYPVGADVSADLLALDVSKSREQLKTRLAVATSAAVATGVPRTNDSVKCLVMQIDLLRQTIATEYQLGPVAALSTPADKCDVEGSQDLVVDYQNAKAKGREALERFAGAVSAELGVRRQVLIGQIDSLVAAAPPGLAARKAALAQDLKLLDALITDTATILDGAVNALDVAVKEARALARDPQKAAEVHAKVAEALTREGDFFEPYGTNPEPTGHERMLEMTYRDAFQWYFLQPWNGLPMRTDGEITPSPTIAIPVIDVVGLRYQWAASRFAELRIAPFASMVLTDSAGGNDKDDGPDVIRWAWAPSVSIGNLRMGLAILPFANEQGNAARYVRFVFGADLYKLITGTAIEAL
>NC_021658.1|WP_020735699.1|5313630_5314128_+|hypothetical-protein
MNESSAAPCSPRVAASAAFLCFAPVIVSFAVAPGALWPEYPGLAFHLAVFALVPSLRAPEWARMAGYGWLFLDVTTGVLALNDVPRAVADPVRLGAHIFAGIWIVTASRAASLPVKLVGVPAGALLFAYSFVSPFLPPTVLAPASILMMVWFALIAWQNGSQRRA
>NC_021658.1|WP_044985953.1|5312611_5313466_-|helix-turn-helix-transcriptional-regulator
MPRDAAPVRTELRAYDDVPGVRSLLVDADERLWCAVKETYAVALIHRGRAEFWSRRGGVASAPGDLHFDAPASVHRDLRRDGPARFQIVTFDVALVREQAERRGLRPSLSLRVPLLERRHPDRRPLLALHRAYRGRPDPLTRQVVVAEALDALVRQLDGADARPHASVARGRLGRAVELIHARLGEALSLDDLAAAAGLDRFQLCRAFRAEHGIPPYTYVLRMRVARAYAWLAAGRPVSEVASALGFCDQSQLHGHFRRAFGITPGAFARVARRGHAPLAVVER
>NC_021658.1|WP_020735708.1|5330281_5330716_-|hypothetical-protein
MKDPAQDVEVYATLAARLADPGEDRAALLAEHGLDEAGWEALDDAWQARLSEADEDDGDEVGVPPLVAAFAETFARVQRGRARSELSFERFLEAARAMKRGTDMATVLSRLDLTLEDYLSAQQRWTAAMLEDDELRAQFQRAMR
>NC_021658.1|WP_020735709.1|5331513_5332839_+|hypothetical-protein
MVGMQRAPLLGDPFRGALVLERRMLAAIDVIAAIGAPALEHVPRLVTEAPVKDPSLAFASAMVLGCFAGRDALAAAELALLRSDRDKAFIEALGAALKLVPHELLPLALRGLLREPEPLVRAMAIDVLAYRGLATEDELVAAASDEAAPVAARALTHLGCGASQRLPELIQRALAAEDPALREAAWTAMALSDHPHASIALRGAIEAPEGGDAAALLLAIAGDEADARHLVARAFEAPREGLLAAVGWTGAASAVPPLIDLLERDGAKAVKLAAAFALDRITGAGMWEEVAVEDEEIVVADPPDPDVGEPRELKLAQLVSDPRDLSPAPAPELVELPTVDAARWRAFWMERCQGWDLGARYRRGRPYSPEVVLDELDAGRVTPAERRHLQRELIVRTGVFVRFDPHDFVVAQEEAIEAWRPIAARASGAPGRWTRPRRRAG
>NC_021658.1|WP_020735710.1|5332766_5334326_+|hypothetical-protein
MAADRRARLGRAGALDAAAPARGVSEAVAERLVRRAGHGGRMNSSAEPSRRAGGALRRPCRAARHGGTMARAGPCAREGIMDQGGLRKTGRRILAAAALGAALVAAPPARAQTKEELAAARVLFQEGVALSAANNCAAALAKFQAVAGVRRTPQVLFNIAECEARLGKLVSALGNYRMAAAAAAGDPRANDVTANVGARIEDLEARVPRLAIRRGAGALTATILLDGTALGAAEMSGDIPVDPGPHVVAARIGGREVVRETITLEEGHAKTVEITIAEPPAAAAPTAGAPPPGAPAATAASAAPAAARPSKAPGLVALGAGIALGAVGGVFLGLRAGTLSDLDALCGGDRSCPPSARPTADRGRLYTGVAEAAIGLGVASVAAGIVLLATSGGGAEPRRGARPPRGGPAAGARRRPHGPQRRRQVLRPPGPLRPGRLGARGPAGALRAPQPWLWQQNVLGAAPRAVPVAAPPLGAHAPPVGVADVTLRPTIVGFPSRSSHPPARTSTTGVSHVSSALSA
>NC_021658.1|WP_063751998.1|5335344_5336082_-|OmpH-family-outer-membrane-protein
MQDNAPERPTARCSTPSSSVRSADASRCAAPPARRAAGRRPAARLLPLLAAMALGGAALLSPAPASAQSKIAVVDVRRAMLETEEGLRVQATLKKLFDSRQVELDTKQRALADERDKLDKEAQAGKTPKDALQRRFETWQRQAAELQATMVDYQREMQRKESELTTPILQKVLGLLRRLAAQEGYDLILDKSAAPYYRADLELTDRAIQMYNSGQVGDAAPAKGAPPAKGAAPAAPAKPAAPAKK
>NC_021658.1|WP_020735713.1|5336115_5340243_-|protein-kinase
MLPEFTDPTDRFMIEARSRSGGMGDIFKGTDQTTGAPVAIKVLRAAASPQERARFAREIAILADLRHPNIVQYIAHGTWLDGRLFFAMEWLDGEDLGQRQRRAPLGLRDSVEVVRRSAAAMAAIHARGVVHRDLKLSNIFLVRGKGTAIKLIDFGVVKLATPDDCPTERGTIIGTPHFMAPEQARGEPVDARADVYSLGSVLFRLVTGRNVFETEHAIALLGRLVLEDPPRAQQIRFDVPEALDEVITRAIARDREVRYENGGELARALARVGELNNDPPATDRSASAIRRAAAPEVRSGPASPAGPSDERPQVRLATSERRVVACVLFELGAGPLRPEVDAALRDVLGDDARLEPLLSGKMVAVLGVERSRGDEAMRAARAALTVARSTPGARVSVAVGHAVRGRANLAGEALERAAQQLESAVPGAVRIDGYATAALEGRFVVQEDARGGVLVHEDAAGFDARKLLGPPTPTIGREHELARLQGIYSDIAEDAVPRAALVTGPAGIGKSRVRAELIQRLDMAPHAPVILLCRGDPMSQGSGLSGLGRALRALMGIHDGERLDEQVQKVNAHVAVRLARPLRFLAGFIGELAGVPFPNDGNEPLRAARESPQLMESRTRMAIEAFFRSKSESTPQILVIEDMHWADSTTVELVDWLLGCTDLRFGVFGFARPELASRFPSLWQERNVTRIALSPLSPQAADRLVATALPQADPATRGAIVQRAGGYALFLEELIRHAAEGRDDVPLSVQALVQHRVDRMSSGVREVLRAASVFGPVFWTAGVEALLERAVGAELAELEAGEIIARQLEPRVAGHAQWTFRQSLVRDAAYASILEEDRAALHRAAAAWLESAGDVDPGLVARHAEAGGEKTRAALLYARAARAAVASGAELDAALDLATRGLACGAEGTTRATLLVHRGEVCELLGRAPEGLDAAEEAARLALPGSDLWGEAQLLAVRCMIAAGESAEADARAASALSPQFAAALSPQIRATLLASRVRALVDLSRPAEALGAAEAAVEVARASGSTAALLHTREAHLAALMHVGDLSAAASAGASLVADADAEGDAVIAAKARLNTGSVLNQLGLFEEAQALLERALHGARSRKLRALEGFALHNLGMSYARLGNLEEGIAHERQAGRIADECHVARLRIAGRLYEAIFLVWRGAPGDYGTAHSIARWLCEETARHATALQAMASFALARVQLARRELRAAVDAAREAARHLEGGPIEEWNDAIRLTLVEALLAAGEEREAHAALDAAFTALRARVDALRDPRHREAFLRGSDDVGRLIALARERLGRSVPAASAADASVHRAAAAPSRGRGATKTASAVSRKDRADAPGGDPAGQRGAGPAQGKEAHGDGAAAPAREKGAPRS
>NC_021658.1|WP_044985956.1|5340523_5341576_-|hypothetical-protein
MPRFSLFKIVFASLLLSAPAPAAEPARRTLRMHYSEDPRAASCPGEGALREQVRRRTGYDPFREDAPEAVDVAIAPRGAALVATLKYRDEDGTESVPRDFNVPNGDAACALLTSYVALSIAFTLTPFWLDEQVPATAPPPPELAPPPAPPPAPPRPRAPPARPLPATEPAGRRSAIRGGTGVFAQIGLTDQLVGGASWFCEARWSDRLSVGLEVQDAFLPLSAGPSEGGWSLGASSAGGRSDGQPVHTRMLVTTALVPCLHTNDLLATCTVVQLGVLTLAGQPGGQSGLLLMFVALGLRTGVEFALNDRLSLSTHLELLTAVGLKKRPPVDVLRAPHLSASVGAGVIAAF
>NC_021658.1|WP_148314827.1|5342016_5342988_-|protein-phosphatase-2C-domain-containing-protein
MLQSTIKRPSAPSYGGDDDDDDDDDDEHEREEPSAVPIIYDDEAAVDEPTSSSPLLLISAVGQTDPGQKRKKNEDCYLCLDEHYLFAVADGMGGHAGGDVASRLAVDTIARAFKDPSFLDSDAESPYPDVPRRGSELAVAIQRANQAIYERAHAERSLTGMGTTLVSARFSPNKQRLYIGHVGDSRCYRLRDNELTQLTTDHTMGAAGITGPMANHLSRAIGISPAVKVDLIIARPHPGDVYLLCSDGLSKMATHEAIRDVLLAEPDPEKASQALIEKANAGGGRDNITVILVRVSDPKDLARLASRAGAGAGAGAGAGAGTG
>NC_021658.1|WP_148313694.1|5344037_5345771_+|hypothetical-protein
MKLGRALLQTPRIVGVGLAASILGGLGGAGCFVDSEGLPPPGNGLYFPTGLAASPGGRVLYVANSDFDLQYNGGTVQALDLQRLRKRALALQAALAPAEAGDGVTVSAACGAVGLGTNPAPLLYPGPCAPLDLSSLQGDEAVVRSSAVIGAFASNVLLVHRPLLGDAAGGDADAPKARLFVPVRGDPSVTFFDVADDRLDAPDAQRCSGDSCFQLDCGAAEAGGRCGRDHRIGEDPGQELLRRKLPLEPFGIAAGPDGTSVVVSHQTEDTASVIVNPWERGKRPQLAAVLTDLALGPTELAAVPRPRLVTQLKAADQEIDYEPAFALTFIAAPQLDLLSYREASEGAAALLSQSNATQITALANGTDSRGIAIDAHERQACEAGCGDADYACLARCTEIPLELYVAHRFPNSLLIGEVITTLVENASADPERPEERWASAYETVEIRGAAPLGAYPSRVEVGEVIGKDNQRHRRVFATVFDSGLVFSYDPEARRIEATITTGRGPQALAFDTGYACGDEKERCDCAPGSDGCEPYSLMYIAHFTDSYLGVVDLDLRKNLTPSMILTVGTPVPPRESQ
>NC_021658.1|WP_044985957.1|5345767_5348656_+|hypothetical-protein
MKLRVAVIAPASVLALAGCAEDPEPVAVEALSQSGQSAFVCLAVDRPDPNAPGVVRSLPITDCGDRTAKSPSDFGVDAASGGKATLPHLYALVTQTLRGEIAVIDMTTESAPILDQDTGTPGASFLPIGAQPVDIIATPGGTASFVAVAEPGRAGIFALPSAKVVPRTGCPVPSLTSWPACSLPSAPGEVLLAADPPDADGKLRASCSGAYDVEPASPEEAEAGGDACGGGSGDLSQEGLGRQKLLVSMPELGGFAVIDAQTLLQDERYQEGGFAPCEVERWIPLEVSLPVSPPAPAPDEAPEGPAACVQPATPASPAQAVASPRPAGLALAGDRLFIGDLDAPVIHVVHLPTPCAPTELPPLLPASTLDPARVVTTSRIALSQALPPDFRRYLYAVDAGDGSVMVFDVSDGASSRSPLARPHPEWNPFQPPDRIRLTAPVRDLAIVHRDAPAILPATGVAPEGLRCDPDPDLKQCDINVASCDLETLYRTSPGRDAGAGPLKLRGSFAYLALTNGQVAVVDVDDLDAACRGPERQSARAGCAGAPAGGDPLKTSGEVSCNVVLPHALRSEAYVATNDATGVLEPGVQSLPILYDRSGTVAQLSAESPKMRATLPPEAEAPALALAVGAQREAIASADTGDSALDEQGLVLRSGEPQHALAMNLEDPRVHLVNEAWTVTYEGTLPGFTRTFVHFDEGAAVRSGDARFCRRGVQSRASVREQLRAAGAPEGEVDAQAAELADFVQITSELPGEDAGYWDEVDPAVCSFESCNAKYGSVITSRPGLRVAEAYEDRLALESRDPAVDEVAFAACCFPGEVQLSVRPARQWVVRSNATGFLHHVIADPETGRCRNSCDARLARLNGRVAHTLVDGRVTDGAPGAFVNPMFRFAITGGVPEQDMQFRFTTQGAFNPLFIDLVRNEVELQPQAIRPVPATGEIAVTDGSFEGLILLGGNGAEVVRQFH
>NC_021658.1|WP_020735716.1|5348786_5351489_+|DNA-mismatch-repair-protein-MutS
MQLSEQPAARKKLTPVMRQYEDAKALHPDAILFFRMGDFYEMFNDDAVLVSRALNLTLTSRNKGEPEEVPMAGVPHHAAHGYIARLLALGHKVAICEQCGDPSKIKGLVPRQVVRVVTPGLVTDTEQLDARANHYLAAVDGGGARRGDAGDAGAASGPYGLSLLDLSTGELSATSVPDAATLLAELSRADPREALIARDLPDIRAAATSLSCRAALRDDDELDSADVASILDDAAIEPISAAALAEHPLPAVRAAARALRFARRCSPGARIPVRRIAPHDTSGTLRIDETAQAHLELARAADGGRRGTLLDVVDCTVTPGGARLLRRRLLTPLADVAAIRRRLDEVELFVANPRARGELREALGGVGDLERLSVRALLGEATPRDLGCLRDGLAAAPAAVAAVRSIPDLGDGGAAPLLAEAAAVDVAADVCAELTAALIERPPPNAREGGIFREGYDKELDEARAVEKNATELILALEAKLRSQTGAPSLRVKYTRVFGWYIEVTRAHVAKVPDSFRRKQTVATGERYTSDELDELADKIEHAGARALEREASLFERLRGLVAKSEGRLRALARRLAAWDVAAALADVAHRNDYVRPHVTAGEAIAIRDGRHPVVERYAAAGHFVPNDTRLDLSGERLWLITGPNMAGKSTLMRQVALIVVLAQMGSYVPAREAEIGLVDRILSRVGASDNVARGESTFMVEMRETAEILRDATRRSLVILDEIGRGTSTYDGLAIAWAVAEHLFDAIGCRALFATHYHELTELSARAPGIANYSVAAREHGDDVIFLHKLEPGPASRSYGVAVARLAGVPEGVLARARAILATLESGAALPGGKHASLRGRTRGGAAQLDLFVPAQAAVTPEQAAVLETLRSVDVDRLAPLDALRLVAKLKGLLGGAGK

Crispr_ID: NC_021658_18

• CRISPR_ID: NC_021658_18
• CRISPR_location: 5769470-5769597
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_18

Consensus_repeat	Method
TTAGGTAGTCTAACGATCGGCTTTTCCGCTTCGACGAGGG	CRISPRCasFinder

spacers of NC_021658_18

>18.1|5769510|48|NC_021658|CRISPRCasFinder
TCCTCATGTTCCACCCCGCGGGCGCGTGGCGCCGCGCCACCTGGATCA

CRISPR arrays and Neighbor proteins around NC_021658_18

CRISPR arrays

The CRISPR arrays of NC_021658_18

>merge|NC_021658|18|5769470-5769597|CRISPRCasFinder
TTAGGTAGTCTAACGATCGGCTTTTCCGCTTCGACGAGGGTCCTCATGTTCCACCCCGCGGGCGCGTGGCGCCGCGCCACCTGGATCATTAGGTAGTCTAACGATCGGCTTTTTCGCTTCGACGAGGG

>NC_021658|18|14|5769470-5769597|CRISPRCasFinder
TTAGGTAGTCTAACGATCGGCTTTTCCGCTTCGACGAGGG	TCCTCATGTTCCACCCCGCGGGCGCGTGGCGCCGCGCCACCTGGATCA
TTAGGTAGTCTAACGATCGGCTTTTTCGCTTCGACGAGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020736006.1|5758126_5759716_+|carboxypeptidase-regulatory-like-domain-containing-protein	unknown	unknown	gnl|CDD|379297
NC_021658.1|WP_044988483.1|5777853_5778540_-|queuosine-precursor-transporter	unknown	unknown	gnl|CDD|376842
NC_021658.1|WP_148313728.1|5761544_5762462_+|cyclase-family-protein	unknown	unknown	gnl|CDD|224790
NC_021658.1|WP_020736011.1|5764469_5764913_-|NADAR-family-protein	unknown	unknown	gnl|CDD|271319
NC_021658.1|WP_187345991.1|5759746_5761486_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173874
NC_021658.1|WP_020736026.1|5782562_5783417_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213260
NC_021658.1|WP_148313729.1|5763639_5764398_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044988484.1|5783413_5784259_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
NC_021658.1|WP_020736022.1|5778705_5779689_+|asparaginase	unknown	unknown	gnl|CDD|199208
NC_021658.1|WP_020736019.1|5774170_5776543_-|hypothetical-protein	unknown	unknown	gnl|CDD|371679
NC_021658.1|WP_020736016.1|5769055_5769370_+|cell-division-topological-specificity-factor-MinE	unknown	unknown	gnl|CDD|234718
NC_021658.1|WP_044985996.1|5776853_5777816_+|SMP-30/gluconolactonase/LRE-family-protein	unknown	unknown	gnl|CDD|225921
NC_021658.1|WP_044985998.1|5781516_5782566_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270281
NC_021658.1|WP_063752004.1|5779656_5780901_-|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|368185
NC_021658.1|WP_020736012.1|5764987_5766115_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380537
NC_021658.1|WP_020736009.1|5762522_5763488_-|DUF4423-domain-containing-protein	unknown	unknown	gnl|CDD|373044
NC_021658.1|WP_020736015.1|5768216_5769044_+|septum-site-determining-protein-MinD	unknown	unknown	gnl|CDD|225447
NC_021658.1|WP_020736018.1|5770492_5773684_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223627
NC_021658.1|WP_020736024.1|5781064_5781520_-|nucleoside-deaminase	unknown	unknown	gnl|CDD|223663
NC_021658.1|WP_187345992.1|5766438_5767188_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|214473

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020736006.1|5758126_5759716_+|carboxypeptidase-regulatory-like-domain-containing-protein	gnl|CDD|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	3.07503e-07
NC_021658.1|WP_044988483.1|5777853_5778540_-|queuosine-precursor-transporter	gnl|CDD|376842	pfam02592, Vut_1, Putative vitamin uptake transporter.	2.09742e-35
NC_021658.1|WP_148313728.1|5761544_5762462_+|cyclase-family-protein	gnl|CDD|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	1.23306e-46
NC_021658.1|WP_020736011.1|5764469_5764913_-|NADAR-family-protein	gnl|CDD|271319	cd15457, NADAR, Escherichia coli swarming motility protein YbiA and related proteins. This family of uncharacterized domains was initially classified as Domain of Unknown Function (DUF1768). It contains members such as the E. coli swarming motility protein YbiA. Mutations in YbiA cause defects in Escherichia coli swarming, but not necessarily in motility. More recently, this family has been predicted to be involved in NAD-utilizing pathways, likely to act on ADP-ribose derivatives, and has been named the NADAR (NAD and ADP-ribose) superfamily.	8.76314e-71
NC_021658.1|WP_187345991.1|5759746_5761486_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173874	cd08509, PBP2_TmCBP_oligosaccharides_like, The substrate binding domain of a cellulose-binding protein from Thermotoga maritima contains the type 2 periplasmic binding fold. This family represents the substrate-binding domain of a cellulose-binding protein from the hyperthermophilic bacterium Thermotoga maritima (TmCBP) and its closest related proteins. TmCBP binds a variety of lengths of beta-1,4-linked glucose oligomers, ranging from two sugar rings (cellobiose) to five (cellopentose). TmCBP is structurally homologous to domains I and III of the ATP-binding cassette (ABC)-type oligopeptide-binding proteins and thus belongs to the type 2 periplasmic binding fold protein (PBP2) superfamily. The type 2 periplasmic binding proteins are soluble ligand-binding components of ABC or tripartite ATP-independent transporters and chemotaxis systems. Members of the PBP2 superfamily function in uptake of a variety of metabolites in bacteria such as amino acids, carbohydrate, ions, and polyamines. Ligands are then transported across the cytoplasmic membrane energized by ATP hydrolysis or electrochemical ion gradient. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_021658.1|WP_020736026.1|5782562_5783417_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.53584e-114
NC_021658.1|WP_044988484.1|5783413_5784259_-|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	7.69614e-55
NC_021658.1|WP_020736022.1|5778705_5779689_+|asparaginase	gnl|CDD|199208	cd08964, L-asparaginase_II, Type II (periplasmic) bacterial L-asparaginase. Asparaginases (amidohydrolases, E.C. 3.5.1.1) are enzymes that catalyze the hydrolysis of asparagine to aspartic acid and ammonia. In bacteria, there are two classes of amidohydrolases. This model represents type II L-asparaginases, which tend to be highly specific for asparagine and localized to the periplasm. They are potent antileukemic agents and have been used in the treatment of acute lymphoblastic leukemia (ALL), but not without severe side effects. Tumor cells appear to have a heightened dependence on exogenous L-aspartate, and depleting their surroundings of L-aspartate may starve cancerous ALL cells. Type II L-asparaginase acts as a tetramer, which is actually a dimer of two tightly bound dimers. A conserved threonine residue is thought to supply the nucleophile hydroxy-group that attacks the amide bond. Many bacterial L-asparaginases have both L-asparagine and L-glutamine hydrolysis activities, to a different degree, and some of them are annotated as asparaginase/glutaminase.	9.98788e-127
NC_021658.1|WP_020736019.1|5774170_5776543_-|hypothetical-protein	gnl|CDD|371679	pfam11703, UPF0506, UPF0506. This uncharacterized family is found in Schistosoma genomes. Although uncharacterized it appears to belong to the knottin fold. The sequence is composed of two repeats of a 6 cysteine motif.	0.000113959
NC_021658.1|WP_020736016.1|5769055_5769370_+|cell-division-topological-specificity-factor-MinE	gnl|CDD|234718	PRK00296, minE, cell division topological specificity factor MinE; Reviewed.	2.48655e-36
NC_021658.1|WP_044985996.1|5776853_5777816_+|SMP-30/gluconolactonase/LRE-family-protein	gnl|CDD|225921	COG3386, COG3386, Gluconolactonase [Carbohydrate transport and metabolism].	2.30562e-21
NC_021658.1|WP_044985998.1|5781516_5782566_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270281	cd13563, PBP2_SsuA_like_6, Putative substrate binding domain of sulfonate binding protein-like, a member of the type 2 periplasmic binding protein fold. This subfamily includes the periplasmic component of putative ABC-type sulfonate transport system similar to SsuA. These domains are found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	5.21947e-67
NC_021658.1|WP_063752004.1|5779656_5780901_-|amidohydrolase-family-protein	gnl|CDD|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	0.000747926
NC_021658.1|WP_020736012.1|5764987_5766115_-|substrate-binding-domain-containing-protein	gnl|CDD|380537	cd06314, PBP1_tmGBP, periplasmic sugar-binding domain of Thermotoga maritima glucose-binding protein (tmGBP) and its close homologs. Periplasmic sugar-binding domain of Thermotoga maritima glucose-binding protein (tmGBP) and its close homologs from other bacteria. They are members of the type 1 periplasmic binding protein superfamily which consists of two domains connected by a three-stranded hinge. TmGBP is specific for glucose and its binding pocket is buried at the interface of the two domains. TmGBP also exhibits high thermostability and the highest structural similarity to E. coli glucose binding protein (ecGBP).	5.96753e-37
NC_021658.1|WP_020736009.1|5762522_5763488_-|DUF4423-domain-containing-protein	gnl|CDD|373044	pfam14394, DUF4423, Domain of unknown function (DUF4423). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, and is approximately 170 amino acids in length.	6.27534e-28
NC_021658.1|WP_020736015.1|5768216_5769044_+|septum-site-determining-protein-MinD	gnl|CDD|225447	COG2894, MinD, Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning].	1.78884e-162
NC_021658.1|WP_020736018.1|5770492_5773684_-|DEAD/DEAH-box-helicase	gnl|CDD|223627	COG0553, HepA, Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair].	1.81483e-134
NC_021658.1|WP_020736024.1|5781064_5781520_-|nucleoside-deaminase	gnl|CDD|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	2.65822e-32
NC_021658.1|WP_187345992.1|5766438_5767188_-|trypsin-like-serine-protease	gnl|CDD|214473	smart00020, Tryp_SPc, Trypsin-like serine protease. Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues.	2.27499e-19

Protein sequences

>NC_021658.1|WP_020736016.1|5769055_5769370_+|cell-division-topological-specificity-factor-MinE
MSIMDYFRRSQPKSATVAKERLQIIVARERVRPTGEPDYLPRLKQELLQVISKYERIDLDQVSVNVERSGDCDVLELNVVLSESERAAVRAAASRAGAPAARSF
>NC_021658.1|WP_020736015.1|5768216_5769044_+|septum-site-determining-protein-MinD
MSKVVVVTSGKGGVGKTTTTANLASGIAALGYKTIAIDFDVGLRNLDLVMGCERRVVYDLVNAIRGEATVRQAVIKDKRIETLYVLPASQTRDKDALTMDGVGRILDELRAAGFDYIFCDSPAGIEWGAQMAMYFADEAIVVTNPEVSSVRDSDRVLGLLDAKTRRAELGEEPVKTHLLLTRYAPARVAKGEMLGHKDVLELLGIPLLGVIPESQAVLQASNAGTPVVLDPTSDAAQAYLDVVQRFLGEERPHRFLEPAKKGFFSRIFGGQAATA
>NC_021658.1|WP_187345992.1|5766438_5767188_-|trypsin-like-serine-protease
MVAAILSACTGEVDDLPLAETDEAPAGIIGGTVDEGDPAVAMLRIYPEGEDFGEICTASLIAPKVLLTAAHCVTPEKVDGGTVTAFFGTDSYGEEGFWVNVVETHIDPAYDPTNKQAGHDVAVAILEEPVAIQPLPYNRVPLTADRVGEPGRLIGFGDDHEIWGFGGVKYHVSTTVHTVTPSLVGLGDRDHHTCQGDSGGPALMDVSGVPTIVGVTSFGGVQAPSICTDGWHARVDLSLDFIDPFVNAP
>NC_021658.1|WP_020736012.1|5764987_5766115_-|substrate-binding-domain-containing-protein
MKTMGRCWAAFGLMLAAAACGSGDAGGEGTESDTITRAEIPDNEFLPMELEARIDSLVAELNKTSLEPMQMVVLTKNLSDFFEPISVGANRAIGELEAIGNVLGPTDQSDDDPTTTQDLQNQQIQQAVADGAKGIGVSPFGDVNKATINEAVDAGIHVVTFDSDLVDSKRSLYVGSLGYSAGKKAASTLLEMLPDPPGTVLIQGVTGKDWPDAFDRTQAAQDVIGKAGYTFTVTPAVFVGDENADVDQMKAVLQAANPPVVGMLGLFNISYRLVMAADAAGIEGVPIVAFDYDPKTVEYMREGRIQATHTQRQYYEGYLVPYILYGINTIGLDATKQILAPLVDDKGRVNIGIDVVLSDKIDDYNDFLNTIGAIQ
>NC_021658.1|WP_020736011.1|5764469_5764913_-|NADAR-family-protein
MTVIRFYRAGDAHGFFSNFSRHPFTLKGKVWPTSEHYFQAQKFAGTDHEEEIRNAPGPGEAARMGRQRSRPLRPDWEQVKDDIMREAVLAKFTQHEDLRRALLDTGDAELVEHTANDAYWADGGDGSGRNMLGKILMEIREQLRRPA
>NC_021658.1|WP_148313729.1|5763639_5764398_+|hypothetical-protein
MSVGLWGCVSGDGGGPSDDAAPGGQIGGVHVEEGGCDEERVDIGVDDVSPLGFSAREALSALSGERSAPLAWSKGGSATATVAAGELVAARFVRSTVATVATVDGGVAAGELVAARFVRSTVATVATVAKSGPGGAESTAIAADCADHLQLDVPLAFSTEDGAFDESFAVTLRVPQVGAGRFFHRIDLDALQGSYEVTEVDPTEFREIFVYLSGELTGSAVSGTISGIAESHPIGTGPDSSVSGQPFSVADF
>NC_021658.1|WP_020736009.1|5762522_5763488_-|DUF4423-domain-containing-protein
MNHEFLARELIRALRGRRSQLGFSRRLGFRTNVVYTWESGRRWPTAATFLVAARRAGVDVAGAVGRFFPSTPAWLAHTDPASAEGVAALLSELRSMSPIVDVARRAGRSRYAVARWLSGEAEPRLPDFLRMVEACSLRLLDFVALFADPAALPAASAAWRTLEAQRRAVYEEPLLPAILLALDMPSYRALPRHEPGWIARRLGFPVEDEARCLDRLAEAGQIRKSRGRWIVAPIRTVDTRPDPDAEHRLKCFWAGVGLSRLTRKAEGRFSFNVFTVSEADLAKLSELHVSYYQNMRAVIAESRPPERVVVVNLQLFPLDGG
>NC_021658.1|WP_148313728.1|5761544_5762462_+|cyclase-family-protein
MTAPDAAPAAAPIHDGSPRGPSGRARHPRGHTLSAHVGGCQLAWIARFLDLFAPLRETDGGSATRSRSREAPPRGDPPKEPPVTTPVSRILVDLSHTVEHGMVTYKGVPAPVLCDFLSREQSRAVYAEGVEFHIGRIDMVANTGTYVDSPFHRYADGKDLAALPLESLADLESVVVEARDRSGRAIDEGAFEGLDLAGKAVLVRTGWSDHWRTDRYFEGHPFLTRGAARLLAGAGAAFVGVDTYNIDDTADPTRPVHSILLGADIPICEHMTGLDQLPAAGARFFAVPVKVRAFGTFPVRAFAIV
>NC_021658.1|WP_187345991.1|5759746_5761486_-|ABC-transporter-substrate-binding-protein
MSRAVPRRALLLSALVLSTGAVSGCRSKGGGAESSSVAPERAAKPEPAASASKPAPKGAAMVTIAREQQATWVRNFNPLLAEGNVRFPTVAGIYEPMLIYNTMRNEYTPWLATSYAWSDGNRKLTFKVRSGVKWSDGQPFSAKDVSFTFALLKKHPALDLSGVWRFLGAVTAEDESTVEFVLRRPYVPGLSYIGHQPIVPAHIWKDVADPVTFANENPVATGPFTEVKVFQNQVYELGKNPHYWQEGKPAVDGLRFPAYPSNDQVTMALVNGEVDWAGAFVPDIERVFVAKDPAHHHYWFPLVGGTATLYPNATRKPFDDVRVRKAISMAIDRDQIVKLAADNYTHGADATGLDDSYERFRNEKAVAAGDWVRFDAQRANEILDDAGYPRGADGIRTRNGKPLRFEINVVSGWSDWVRAVQIIAQNLQTVGIDATMRTYDFSAFFAALQKGTFDMSMGWTTVEPTPYNFYRDLMSTELLKPVGEVSARNWHRFGAKHADPLFHQFEAATDPSDQKRILDAIQMIFVEAAPVIPLFKNPSWGEYSTKRFTGFPTTENPYAKLTPNNPPEYLLVLTELRPR
>NC_021658.1|WP_020736006.1|5758126_5759716_+|carboxypeptidase-regulatory-like-domain-containing-protein
MQQHSSRTSFLHRSSGRLLLLALLAIAIAAAVLLLARPRAEETLSAGSEEAGGETRRSPPTYRNRAVLRSPAPSGSREPERPRIVGEVYDTDGNTLAGATVVATTFEVAGNIPSTARAVKSDERGRFELDLADGTYQLKADLPGYGPTNAVAHSGDTVSLVLSRSGVITGRVLDERREPVRRFTIDVLSAVPDDVPAPPPMYSQTFESPDGTFRIDQIPPWDVILKATAEEHAPGFSDMLSVERGQTGTVELALSRGCALSGRVEDAQGTPLPGVFVDAESRLGAGSLSEQAIQSAADVQQTQTGDDGAFRLEHVPTGAIQVRAYDGSHAVTTLAMNLSDCGKVEPVKVVMAPGGSIRGVARREDGSPIPHAKITLLARSVGFVNVMADEEGSYRIDDLPAGMVRVELRDGSRATMVSVNVKEGKVVKRDISLLGEGTGEIRGRVTAGDKPLAGIRLLVTTNRGRKPGFERHTPVTDKDGNFRVPSLAAGNYLITVMATPVGQGAQVDEGGVTTVNLDVTPKPASKDTN
>NC_021658.1|WP_020736018.1|5770492_5773684_-|DEAD/DEAH-box-helicase
MPLVFLPDELRFFLWDDSAPEGLAARSLGATTPAEAVVVTEAGRAVRKTGEAAPLLDGVSALASMTQDDLGRAPPSVAAWSLASKLALDLVVRERVVPRVAPASAAGERAEARWAASLAAPEDAARVAALARAMPPAAHAVPAGAQADVELLAAAAGAAVPAAGAQAAAAPGGRGGRGRPRAGAAPEVWSAEALLRAFLDAVADALARGSATNRPKAPPRPARAPWEHRLVLALTGPQAAFAAEGLAERALVADLDAWVRPALGACDALRACFRLELPEGDRGFALRFLLQATDDPSLLVPAADVWKARGRTLKALGRAFSDPQEALLGALGAAARLFAPIARALGEARPEQVALEPAEAWAFLARAAPALGEAGFGVIVPGELLASGQRRLRLRLRVGGAARTAGVVAGGAGLGLDEALDFAWEAALGDEPLSARELAALARQKSPLVRHRGAWVVVVPEELAEIQRRLEAGGGRLPAREALEVALAGEAEVDGLSVPVVAEGAFAQALARLRSGAERAAAPPAGFAGALRPYQARGVAWLQTMASLGLGACLADDMGLGKTVQLLAFLSGRRAAAPEDARPALLVAPTSVVGNWEREAARFAPALPLVRHYGEGRARSAEELAARAASARGDGSPGGALVVTTYGLLRRDAAALAGVDWAAVVLDEAQNIKNAASRTARAARALRAPHRIALTGTPVENRLAELWSILEFANPGLLGPLEAFRRAYAVPIERYGNREAAERLRRIVGPFLLRRIKTDPAVVPDLPPKIEARVFCALTREQVTLYQAALDEAMRRIEEAEGIARRGLVLALLTMLKQICNHPAQYLGEAGPLAGRSGKLARLAEMLEEALAEGDRALVFTQFREMGERLVRHLATSLDTEVLFLHGGTPRLARDEMVRRFQDDPRGPRVFVLSVKAGGAGLNLTAASHVFHFDRWWNPAVEDQASGRAHRIGQRSAVQVHKLVCAGTVEEKVDRMLEQKRDLAARVVGEGEAWITELDDASLRELFALSRDAVALAGELDDRDEPEPEDGRPEERGAPGERPAEGRRPGLARGVTRRGEART
>NC_021658.1|WP_020736019.1|5774170_5776543_-|hypothetical-protein
MVALSLGVALAACSAQGPGSETSAASGGGVGGGGTATGGGDSSSSGDDFNPTGPGVGGDGGSVPLGFTVQPNDLQTIAVAAGQAAPSVSYTATRMDAPINVGWSVDRGELGAISAGPASTATFTPKGTMGGLVTVRAGLNGETVERNVLIRLTAAQNGADAAVPAQAQQIATDPTQLTLGGGVGGVGGEGLGVAVTSTATLDALEHPASDGGAEQLKFLYPYDGTVWPRGLLAPLLMWQWTPGDADAIKIELRTTSGSFSWTGTFGRPEILSTTGRPFIRHPIPQDVWTMATDSAGGPTPDGSPDRLTVSLTVAREGQAYGPISQTWTVAPARLSGIIYYNSYGTRLAENYDGAVGGNGRFGGAVLSIRAGDTAPQLVAGGNGGNSQCRVCHSVSANGSRLLVQNGLDSYGLSAAYDLTPAGATEHALSTAAPFAAISPDGSIALTQAGELLSLPSSTRRPTSGIDEVAYELGTPAFSPDGTRVVFNAMSGPGANPRRKLFVMKFDAMTGDFADPEVIVDDSGEPAGTRPGWPAFLPDSKSVVFHHQTDPGNEGDTFGDLRTRRGAKAHLAWASIDGSGTAVPLDLLNGRDGPGSTYLPSLSAPVQMTCTADGTSVGDIDSRHKDDINMNYEPTVNPVASGGYAWVVFTSRRLYGNAATIPPFCSDPRGVDLVENITTKKLWVAAIDLDATPGTDPSHPAFYLPAQELLAGNARGFWVLDPCRSEGAPCDTGDQCCGGYCQPGSDGELICSNAPPGGQCSHPQERCETAADCCDPTNRCINGFCAVEGPL
>NC_021658.1|WP_044985996.1|5776853_5777816_+|SMP-30/gluconolactonase/LRE-family-protein
MSSVRGFTLDPARIEHVGQGLVRPECVIAEADGTLWTSDARGIATRIDPDGRQATLGPDVGEPNGMAMDRQGNLIVAALSGGKVYKLHRDGRSEVLLDSIDGMPLGAVNFCFIDSRDRLWISVLTRQLPWWLAVAGNIRDGYIVLVDEKGPRIVADNLSMTNEVRLDADEKFLYAVETIPGRLLRFPVRDDGSLGDPEQFGPDNLGIGGYMDGFAFDAEGNIWVAAVCRNGLSVIFPDGSHQTVFEDPRPEVLEAMTLKQKSGTIEPMDLGACAGDTVQLPTSITFGGPDLRTCYMGSLAMPRLLTFRAPVAGLPLAHLR
>NC_021658.1|WP_044988483.1|5777853_5778540_-|queuosine-precursor-transporter
MPGSPSKRAGRDLASAVGPAAIIVISFYIAAQLISQIASLKIGVVFSLAVDMGTFIYPLTFTLRDMVHKTIGKRGAQTLIFCAGGANLLMALYLLWAARVPSDPSWGLGEQYSAILSPVWRIVLASIVAEIVSELLDTEIFHRVREAYLRKPGPRRQWLAVLASNSVSVPVDNLVFCLGAFAFVLPFDVIWQIFAINLATKFAMTLISLPGIYLVPDKKSNDVPEQQA
>NC_021658.1|WP_020736022.1|5778705_5779689_+|asparaginase
MPRLHLVTTGGTIASRVDPQTGAAVPAVRAEELVAGVPALGRVAEIAVTELCLESSWNLGPDRIAEVARAARALQADPEVAGVVVTHGTDTLEETAFGLDLLLDGDTPVVLTGAMRDASTAGADGPRNLVSAARVAVAPAARGLGVLVAMNDEIHAARWVMKTHTTAFGTFASPGAGPLGAVDGEGVRVFARPARTPQLPLASPEPRVYLVKVASGMDDLLLRALLDARARGVVIEGSGAGNVCGSWEGAIAALVQAGIPVVLSSRCPGGRVTPTYGAPGGGRRLEGLGVIAAGALSGPKARLALMFALGAGLDAAGLRAYFDRFAG
>NC_021658.1|WP_063752004.1|5779656_5780901_-|amidohydrolase-family-protein
MRCAGLGARALQRAARQHGHRPFTGDLGAPLSFSGVFMTDRIARLKASPSEAVKEKLDYPVIDTDIHTNDYSPALEDFVATYGGAKLVDDLRKALSSRRRNAENSSGKDWYTQTPEERQHYRTVRSPWWARVTRNTLDVATYHLPSLLAERLEEQGSDYSVLFPNNTLAPLAVKDRGARQALTRAINHYHADLFRKYSDRLTPVAGIPLNTPEEGIEELEFAVKKLGLKAINISGGVRRPIKSIAEKYPPDQHPEIAKYARQPAPEHRNDFAAAGIEKIEDIRDRWVNNFFFGSESDDRTIAAAFNDKANPLGAKINAIYSSDVGHWDVPDLTEALAESWNLVEEGVISAEDFKAYVFENPYKLYTEANASFFKGTRVEEKLKQRAQAKGDERRGPQPGARSEGSPGKAIEISA
>NC_021658.1|WP_020736024.1|5781064_5781520_-|nucleoside-deaminase
MTRDEGLMGRALELARGAQRAGEPPFGALVVAPDGTIVAEATDEVNGQRDFTYHAEVGAVRRACAAVGADLRGYTLYTTVEPCPMCFTAAWLARIGRVVFGCTMAEVTAATGGAQRELAVPARWMNEHSGAPVDLLGGVRDAECLALFGRA
>NC_021658.1|WP_044985998.1|5781516_5782566_-|ABC-transporter-substrate-binding-protein
MKRRTVLQELGAALACLVLSVGCSNKDAAPSAPGAATGPSAHAGAAAPPAAAPVKLTVGHDLWIGYSGVFLANELELFKKAGLTVELKPFSNPGDTLAALAAGQLDVGLTTLQNLAVLHGNSESDVVAIALVDSSNGADAVVAKESIATMADLKGKTVALTLGEVNHMLFLFGLEKSGVSPGDVKITSMSADDAGAAFVAGKVDAAVTWEPWITKATKNGGHVIFSSASMPDTITNSVAVQRSKLAAGGDAYTRLLGAIDQGVKTLRGEPDKAHPIIGKYLGASPEDVKGMLSGDKIYDLADNKQLFGAADKAGPAYASVTSVVDFTVQSKLVKKAPAPEALLDPRFVR
>NC_021658.1|WP_020736026.1|5782562_5783417_-|ABC-transporter-ATP-binding-protein
MKLSLRGVSKTYSGRRGETDALAPLDMAVREGEFISLVGPSGCGKSTLLHIVAGLEPASSGAVALDGERVLGPGAEIGLMFQQQTLFPWLSVRENVRFPLTLAHHRGRAAGGDRDRGAARVESLLRLVGLWDFRDSYPAELSGGMQQRAALARALVGKPEVLLMDEPFGALDAQTREQMQELVLHLIQHHRITTLFVTHDVDEALLLSDRVAVFSERPGRVLATLDVTFARAARSSALKLDEAFLHQKREILALLRGRDRFETQRDRLLFGLTNTQSNAGEGGP
>NC_021658.1|WP_044988484.1|5783413_5784259_-|ABC-transporter-permease
MLVDPKLRAPSRQCGQAPPRWLALGRALPGRARLALAAASFLAMIALYAWLPDREGASAVVVPTLASIGRATADALAAREFWVDVQHSFLRVTAGFAAAALLAVPLGVLAGAFRSIAALLEPPAEFLRYVPVPALIPLVMIAAGIGEGAKVLLVFLGTFFQLLLMTADEVRRVPAHLLHVSQSLGANRREIVLRVLAPAALPGIWGALRMCNGWAWSYVVVAELVAATEGLGFRVLRFYRFIQTPSIYAYLLVLGLLGLGLDWVFRAASRRLFRWTRGAGA

Crispr_ID: NC_021658_19

• CRISPR_ID: NC_021658_19
• CRISPR_location: 5840911-5841018
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_19

Consensus_repeat	Method
CGGGCCGTACCCCGGCGCCGGGGC	CRISPRCasFinder

spacers of NC_021658_19

>19.1|5840935|60|NC_021658|CRISPRCasFinder
GGGCGCCGGGCCGTACCCCGGCGCCGGGGCATCGGGCGCCGGCGGGGCACCGGGCGCCGG

CRISPR arrays and Neighbor proteins around NC_021658_19

CRISPR arrays

The CRISPR arrays of NC_021658_19

>merge|NC_021658|19|5840911-5841018|CRISPRCasFinder
CGTGCCGAGCCCCTGCGGCGCGGCGGGCGCCGGGCCGTACCCCGGCGCCGGGGCATCGGGCGCCGGCGGGGCACCGGGCGCCGGCGGGCCGTACCCCGGCGCCCGGGC

>NC_021658|19|15|5840911-5841018|CRISPRCasFinder
CGTGCCGAGCCCCTGCGGCGCGGC	GGGCGCCGGGCCGTACCCCGGCGCCGGGGCATCGGGCGCCGGCGGGGCACCGGGCGCCGG
CGGGCCGTACCCCGGCGCCCGGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_148313734.1|5837344_5838415_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|379234
NC_021658.1|WP_020736062.1|5832340_5833666_-|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl|CDD|226350
NC_021658.1|WP_020736072.1|5845962_5847435_-|CHASE3-domain-containing-protein	unknown	unknown	gnl|CDD|214599
NC_021658.1|WP_020736061.1|5831423_5832305_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020736075.1|5849556_5849994_-|chemotaxis-protein-CheW	unknown	unknown	gnl|CDD|238374
NC_021658.1|WP_020736069.1|5841644_5842784_-|response-regulator	unknown	unknown	gnl|CDD|381093
NC_021658.1|WP_187345995.1|5830158_5830704_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|349760
NC_021658.1|WP_020736065.1|5835547_5836291_-|pectate-lyase	unknown	unknown	gnl|CDD|367395
NC_021658.1|WP_148314844.1|5842780_5843842_-|chemotaxis-specific-protein-glutamate-methyltransferase-CheB	unknown	unknown	gnl|CDD|234828
NC_021658.1|WP_044988494.1|5834913_5835498_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|226789
NC_021658.1|WP_148313732.1|5830675_5831434_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044988499.1|5848000_5849560_-|methyltransferase	unknown	unknown	gnl|CDD|224271
NC_021658.1|WP_148313735.1|5838564_5840067_-|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl|CDD|374433
NC_021658.1|WP_020736077.1|5852074_5856352_+|DNA-topoisomerase-3	unknown	unknown	gnl|CDD|236078
NC_021658.1|WP_020736073.1|5847431_5848004_-|chemotaxis-protein-CheW	unknown	unknown	gnl|CDD|366716
NC_021658.1|WP_020736076.1|5850149_5851592_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270277
NC_021658.1|WP_044986005.1|5833798_5834788_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NC_021658.1|WP_044988501.1|5856757_5858398_-|SBBP-repeat-containing-protein	unknown	unknown	gnl|CDD|271320
NC_021658.1|WP_020736071.1|5843883_5845953_-|response-regulator	unknown	unknown	gnl|CDD|223716
NC_021658.1|WP_148313733.1|5836271_5837303_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_148313734.1|5837344_5838415_-|VWA-domain-containing-protein	gnl|CDD|379234	pfam13519, VWA_2, von Willebrand factor type A domain.	1.65964e-11
NC_021658.1|WP_020736062.1|5832340_5833666_-|sigma-54-interacting-transcriptional-regulator	gnl|CDD|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	6.52488e-117
NC_021658.1|WP_020736075.1|5849556_5849994_-|chemotaxis-protein-CheW	gnl|CDD|238374	cd00732, CheW, CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together with CheA and the methyl-accepting chemotaxis proteins (MCPs), which are involved in response modulation.	2.65331e-17
NC_021658.1|WP_187345995.1|5830158_5830704_+|AAA-family-ATPase	gnl|CDD|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	7.41304e-23
NC_021658.1|WP_020736069.1|5841644_5842784_-|response-regulator	gnl|CDD|381093	cd17538, REC_D1_PleD-like, first (D1) phosphoacceptor receiver (REC) domain of response regulator PleD and similar domains. PleD contains a REC domain (D1) with the phosphorylatable aspartate, a REC-like adaptor domain (D2), and the enzymatic diguanylate cyclase (DGC) domain, also called the GGDEF domain according to a conserved sequence motif, as its output domain. The GGDEF-containing PleD response regulators are global regulators of cell metabolism in some important human pathogens. This model describes D1 of PleD and similar domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.63246e-31
NC_021658.1|WP_020736071.1|5843883_5845953_-|response-regulator	gnl|CDD|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	3.78389e-73
NC_021658.1|WP_020736065.1|5835547_5836291_-|pectate-lyase	gnl|CDD|367395	pfam03211, Pectate_lyase, Pectate lyase.	2.72857e-54
NC_021658.1|WP_148314844.1|5842780_5843842_-|chemotaxis-specific-protein-glutamate-methyltransferase-CheB	gnl|CDD|234828	PRK00742, PRK00742, chemotaxis-specific protein-glutamate methyltransferase CheB.	9.96803e-115
NC_021658.1|WP_044988494.1|5834913_5835498_+|HD-domain-containing-protein	gnl|CDD|226789	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown].	1.13607e-33
NC_021658.1|WP_020736072.1|5845962_5847435_-|CHASE3-domain-containing-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	4.27085e-48
NC_021658.1|WP_044988499.1|5848000_5849560_-|methyltransferase	gnl|CDD|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	2.36307e-63
NC_021658.1|WP_148313735.1|5838564_5840067_-|right-handed-parallel-beta-helix-repeat-containing-protein	gnl|CDD|374433	pfam16208, Keratin_2_head, Keratin type II head.	1.40002e-05
NC_021658.1|WP_020736077.1|5852074_5856352_+|DNA-topoisomerase-3	gnl|CDD|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NC_021658.1|WP_020736073.1|5847431_5848004_-|chemotaxis-protein-CheW	gnl|CDD|366716	pfam01584, CheW, CheW-like domain. CheW proteins are part of the chemotaxis signaling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and other related proteins that are involved in chemotaxis. The CheW-like regulatory domain in CheA binds to CheW, suggesting that these domains can interact with each other.	4.26395e-06
NC_021658.1|WP_020736076.1|5850149_5851592_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270277	cd13559, PBP2_SsuA_like_3, Putative substrate binding domain of sulfonate binding protein-like, the type 2 periplasmic binding protein fold. This subfamily includes the periplasmic component of putative ABC-type sulfonate transport system similar to SsuA. These domains are found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.72512e-128
NC_021658.1|WP_044986005.1|5833798_5834788_+|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	3.90862e-14
NC_021658.1|WP_044988501.1|5856757_5858398_-|SBBP-repeat-containing-protein	gnl|CDD|271320	cd05819, NHL, NHL repeat unit of beta-propeller proteins. The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.	4.09651e-07

Protein sequences

>NC_021658.1|WP_148313735.1|5838564_5840067_-|right-handed-parallel-beta-helix-repeat-containing-protein
MKGAVLSLVFLGCAVLVSCSGAASSPGASDEAVGQGGTGAGAPGSASGQGGGATSVGHGGSSSAATGPGGAGGSGGSGGSGDWDGSGGSATIGSGGAGGSIGSGGAGGAGGAGGSGPVEDVGTVIKVTTLDADGPGSLREAIATPGRRIIVFEVGGIIDLDKARLNITEPFVTIAGQTAPSPGITLIRGGMRISTHDVRIQHLRFRMGDAGAAPASGFEPDVTTDGPSAYNIVIDHCSVAWGVDENLSVSGPRFDGPTGTSRRVTLSNNIIAEGLHESVHAKGAHSMGTLVHDYCTDVTVVGNLYAHNYERNPWFKGFATGTIANNIVHNPGKWAMRLGPVVKEWESSGITPEPPRVSIVGNYMQHGVDTLPGLPMVGTNSMGSAYLEDNIVVDASGEPAPLVSPEIVILPEKPVWPDGLVALPAASVVDSVLAHAGARPRDRDEVDLRIVEDFVSGGGMLVNSQDEVGGYPTAEPTTRPLVVPAEDIEGWLERLADELE
>NC_021658.1|WP_148313734.1|5837344_5838415_-|VWA-domain-containing-protein
MLAALYGCASINEGDDSGSGEPSSGEPGPVDPGYGDGTEDPGGVPGDLDPDADPGESVDCGRQNFNVERRPASILLVLDRSASMQDDPSGDEGTPSKWDIVVPALQEVIAATNEAASWGLKVFPQGDRTGTCTEESFPRDILIPIAGNNAPTVNQAISSTTPEGDGTPTGDAINKAVEYLQTIQNDDPKYILLATDGDPSCPKSDSDEFAVQAVTNAAAAGFHTFVVGIASQESKVKALDGLAVAGLEPRQDPDPLAPKFYLAATKDELVTSLLTITGEVSTCLFPLSAPPPNPDHVGVFVGDEAVMQDTTGTNGWNYTGPDMTTIQLYGAACEQVASSGAGAVKVIFGCKDDPIY
>NC_021658.1|WP_148313733.1|5836271_5837303_+|hypothetical-protein
MGVGISIGISSPSGSSPPAPPVPLLVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLADVVLAAVLLELPPPPPPPPPLPVVVLPPLVAALLLELLPPSPSSGVAASSEQPSWEAPAAPSTSSKVKADFNPNLISLPLFQITMDDPRRERSHDGGRRRRRGGNHEPTLHVVERASGSSGLRECKRRSSGRHVASGGRADVGRGLRVNARSTPVDDRG
>NC_021658.1|WP_020736065.1|5835547_5836291_-|pectate-lyase
MEIPTPTNGAGEIRTQTTVLKNAANGGQDVYDFNNQKIGVNNTADCDDGEGQKTVFEVEDGVTVKNLIIAGGLPAGNGIVCKGDCTLDHVYWEDVCEDAATNSKDGATMRINSSIALHSADKIFQHNAKGGSTTIVTNSYIADFGKLWRSCGDCTANGGPRNLIIDNVRVDKVKTTIAGANQNYGDTVTITNLYVKGGYDAEDDKPKICQEYRAVTDHMGESEKLHGGASQWNTATCRVSKSDIKSW
>NC_021658.1|WP_044988494.1|5834913_5835498_+|HD-domain-containing-protein
MPEPLWSAVRAAYGEPGRAYHDLAHVREVLRRVAEVGRDVGWRRPREVVLAALFHDAVYAPGRRDNEERSAELAREAVARWLPGEGLDEDLIARLILLTARHGSLAPADVGEDEALFLDCDMAILGSDAAAFDAYDRAIAAEYGAVPPERYAAGRRAFFERLLAAEHIFLSPYFRERLEARARDNLRRKLGVGS
>NC_021658.1|WP_044986005.1|5833798_5834788_+|GGDEF-domain-containing-protein
MPEFTPAEAKTLSQCVTRFTDAFRRDVADVIRREFRGYEPPEVTELIGQLSLLGRQLELRQPHVPIHETQGPLLKRILIDLRRDSATAIEEPLQKAVNADTIRHLRREVHALEQLMAAPWFAATRALQVPRLTDYMSIRHAEAVLPEAPPLRPREYDEKFHILEAPGLFLPDLAHYRARCALRGAAIAVAFIDIDDFKAFNVQHTETAVDLHVLPPLMESIEAHVFGHGHAYRFGGDEYMITLPNATRAWAVDLLRALQARLARRRYRRVERAPTISAGLCVADVDCFLTDREIQGRANLAKNHAKATEKGRIATYDGELFRPEDLVLA
>NC_021658.1|WP_020736062.1|5832340_5833666_-|sigma-54-interacting-transcriptional-regulator
MHDSTRTITTLRSDAVELPDLRVIVTPQKSPPIEATLGVAPLVLGTSGECDVVIPDSRVSRRHCQLRFTPRGVALTDLGSKNGTFINDVLIVEGFLTPGAIASLGGVPLTVRVAGAPVVVPLSTSASFGEALGSSVPMRALFARLERAAATSETILLLGESGTGKEVLARAIHEASPRSGGPFVVFDCSAVAPNLIEAELFGYMKGAFTGAQAARAGLLEEASGGTLFLDEIGELPLDLQPKLLRALEARQVRRIGAAAYTSFDARVIAATHRDLQGRIGTGSFREDLYYRLAVVEAVVPPLRERKEDIPLLVERFLAAQVPPRSLADLPPNALELLRGHHWPGNVRELRNTVARLVLFPHLAEEAIVKVAPRPADMGVVQFASLPLREARDMVVEQFERTFIAMKLRDSGGNVARAAASMGVSRQLVHRLMERYGIRSKG
>NC_021658.1|WP_020736061.1|5831423_5832305_+|hypothetical-protein
MASKRQRRDSPRERLLAEVGRQVERRLGGSGSELATSQQTLAYLNWLAWHCGGFAAVPAFLNAARADILAILHAGALGVERTAHVHARSLLENLVRHCYFDSRPSLFVARSLLPEEDVRDVWADLLKEIQRLPHFQPALGDTPETAFLFSEIEHAYRQSSRFVHGSTARYRSLYWNIRSIDLDADRARDLDAALRRLGEACLLLLALYHLGPYLLVSQPIRRFMLRDAMDAGGRTRFLRCMESVPVTWAQHQRAAALRARRERRRKPFPTSDGLLLDRKGLALVASPRSSIKP
>NC_021658.1|WP_148313732.1|5830675_5831434_+|hypothetical-protein
MTSPERTGSDGVRAARALLSLVEEHSADDFQAAEAILGGQQELAQVLQLLRDFKRQQSSTDEDHGPVSIELLLEIAKDELLKLAHDNADVEKKLRGVLDTSANVRPDSPINDVIEQGLRNLDNLRLAPTARAFTIAELLRATSETAGAEHEKRIESILRNLAISAIEENVIVLPTLHSIAQLRKMWAPVPLPYKAQESRRHLAERLFKDVERLAPARIGGITTHLLAEGLRGPADRAIAETRRINRKKAHGE
>NC_021658.1|WP_187345995.1|5830158_5830704_+|AAA-family-ATPase
MQEIAAEIVVSRIKKWLPRAGDAYEHVIIDCPPSISSVSLAALKAADKILVPMTADQFSLHGLPLLMKALREYKKVLDIRAKVAGVVLSMFPPSRHAIQGPRHRGTCRRSVLCARRRGLRFAASPRGSPRMKPTETPSRRTNRCRSPTNPSTSRSSPSSTRSRTRWGFLEVRRDEPRANRQ
>NC_021658.1|WP_020736069.1|5841644_5842784_-|response-regulator
MKPHVLIVDDSLTIRMDLRTLLTTGAGFVVTACETKALAQKVLKTRAFSLVILDVLLPDGDGLDLLREIRTSADLAHMPVILLSTEIEVRHRIHGLSMGADEYVGKPYDGSYLVHRAMELVSERSSARRAAEGGGSGLSGKKILVVDDSPTYRASLAHVLRQDGCDVIPAQSGEEALSLLSVEGVDCVIMDLLMPGMGGLEAARRIKQSSGTSHIPVVILTGHDDAATRAEGARIGVDDFVLKAPELTMLRSRLRGLFRNRPAPAAGGGAAARRAGSSPDLPPPSSRAGSRARSVFPGAGSLFDQVVAVSGLSSVIGPSTIVRACRRAGIEPWSMSPEDLHRALPAIRETLRMFLSEEDSERGIAAIGLLARDAASAAS
>NC_021658.1|WP_148314844.1|5842780_5843842_-|chemotaxis-specific-protein-glutamate-methyltransferase-CheB
MRVLVADDSRTVRRRIVGALEADQEIEVVGEAGDGEAAIALCEQLRPDVLTLDMMMPKASGVAVTEHVMAYCPTPILIVSASLERGEALGTFDALAAGAVDVLDKPAAGDEGDAWDLRLVSAVKLVARIKVITHLRRKLRPARPPPAAEAPGGARADDGFCRVIAMGASTGGPSAIVEALSPLPASFPVPILLVLHIGAPFAPAFAEWLAGRLAIPVSIATDGEPLQRAGQPGVRLALPDRHLVVEQGRLRLIDGPERHSCRPSVDVLFESVAVEVGERAIGCLLTGMGRDGAEGMLAMKRAGATTLAQDEPSSVVFGMPREAIARGAAQHILSAGAIGPTLLALSRSTRKSP
>NC_021658.1|WP_020736071.1|5843883_5845953_-|response-regulator
MGSDLYKYFRMEAQELADGLAWRLLDLKEQGGQGEPLDQCFRLAHTLKGAAGAAKQLKIAELAHTVEDVLTPFRRDRQPIPAEHMSELMRLIGLIRDEVSRLAAEEPCDPERGRPARRSAHEEVARVDLAHVGALADEIGEAIVQLESLRSSAEALDRAERLTEALGTVSSPEEAVRHLGELGARRAGGLYRELCAALAAARAELARGIDRLSTELRQAQARTRELQLLPCAGVLEAVELAVREAADALGKRVDFQASGGDIRLDSAVITALRDAALQMARNAVDHGIEPEAARRAAGKPAAGQIQLRVEQRGSRVALICSDDGRGVDVAAVRRAVVRAGLRREEEAYDLTAEDALELIFGPGVSTCEALTSLSGRGVGLDVVRETAAKLSGTASAQSQPGRGTTIELVVPISLSSVTALRIEDGGHAALLPLDAARLALRLDAGAIVRGPERDAIVIEDRLVPFARLAAVLGAAEPEGEPRCAVVVGAGASQAVLGADRLLGAVPVVVKPLPAAAGAPPAALGASLDVRGDPVLVLDPRGLVELVRAAGPGGARRRERRPPPPILVVDDSLTTRMLEQSILESGGYEVDLASSGEEGLRKAAGRRYGLFLVDVEMPGMNGFQFTERVRADPALRETPLVIVTSLSSAADRRRAREAGADDYIVKGEFDQRRLLDTVAGLVARARGAAS
>NC_021658.1|WP_020736072.1|5845962_5847435_-|CHASE3-domain-containing-protein
MKTTWTIPQQIAASLFFPLVVLIALGVVSVHKTASLLEISQELKHTYRVLTELDELHAHFLDAETGQRGFIITGDDAFLEPYEIALHSIDADYEELRRLTEGNLGAQERLDRLRPLMRDKLEEMRLSVEQRRREGAEAAAATVASGRGRRAMDDIRNVAGELRAEEMRALSAREQEAAASEQRLLVTLTAGSALTVLVVAAVGFLIIRGINRRIHSATRRIESSATELQAAATQQAQGSKEQATTSTEVSATMRELLSTSHQIAESTQRVTQIAADTAAAARAGDETVKRAREGIDGVQRQVEQIVLHMLDFGKKSQEIGGILQIINELAEQTNILAINATIEAAGAGDAGRRFGVVADEIRKLADRVGGSTKEIRALIEEIRAAANTTVIATESGSKAVDASARQFGEVATSFRQISELVSSTAEASREIELSTKQQATAVEQVNAALLDVARTARETEASSSVTLKTSSELATLSKDLVRLIQRPAGA
>NC_021658.1|WP_020736073.1|5847431_5848004_-|chemotaxis-protein-CheW
MKRALLAERLAALQAAFDASFAEPARTRAEEPARALAVRAGDRRLLVRIEELAAVEPCRRIVPLAGGPPGLLGLVGLRGRLAAAYDLAALVSGRPRAGVDTAAAGPAPRWLLVCAEHPDIALAIDEIEGHASISPEGARAAAGEREGAGELVTEAVEVDGGPRGLLRVAAVADTVLRRAQRGAERPKEDR
>NC_021658.1|WP_044988499.1|5848000_5849560_-|methyltransferase
MTSAERDLGPLEELLEERLGLSRASLHLGADLEAVLRERARARGCSDLGDYRRALDRPEVAREELHVLAGQLTVGETYFFREWQQIEACVEIALPERFAARQGGEPITVLSAGCASGEEAYTLAIALHTAYPGLLPHRIKVVGVDVNPGAIQKAQRARYSEWTLRAVPDDMRQRFFARAGADVALRQEIVRLVEFQVRNLLDDDPAFWRPGAFDAIFCRNVLMYFAPQKMAEVLDRLHAALAPRGFLFLASSESLRAAGAAFEAAHSHGIFYYRRSSARAHPARGDAPRASRWVARIHEASARVAEVAQRVSPPPRGDAPASPTARRAPPSTRPPSTRPPSTMPPALAELAAIDRALELIGGERFTDAMTALAALPQRAASSARVELLRAVILCQQGDLAGAERACQRAIDAGDAGDGGAAHYVLGLCQEQAGDAAGAAQHYKAAASRDPSFAMPHLRLGLLAKRAGDVAATRDELGRAAALLVSERQERLVLFGGGFPRSALIGLCQAELTARGGRAG
>NC_021658.1|WP_020736075.1|5849556_5849994_-|chemotaxis-protein-CheW
MRALVVRVRSWACALPLTAVVETMRALDVRSVPGAPRFVRGLAVIRGAHVPVIDLATLFGVADGQRGARLVSVRAGARPLSLEVDEVLGIKELDPAALERTPPLVAQALPECVDSLGTLDGQAMALLETARLLPEAAWSALRGTA
>NC_021658.1|WP_020736076.1|5850149_5851592_-|ABC-transporter-substrate-binding-protein
MTKLCPWRWLLCLLIAALGAACTPPEKKAIRVAVGTQNATINCATGGLLLRELDLLKRYLPREGAYEDVRYDIQWRDFSSGPPITAEMIAGGLDFGMMADFPAVLNGIASEQAGKRSIYIATLSGSAAGAGNGIVVPIDSPVHGVPDLKGKRVSVPFGSTAHGMLLRALSDAGLDPERDVTLVSQQPAEAEAALRDDSIDAHAGFVPFVELFPFRGAARKIYDGAATQIPTSHGMLVRAAYAEEHPEVVVGLLRAIVEADRIVERDPERYSEIIEQVTGVDAEVAYMFHGPLGIQTRDVTLKPQFVRGLRVAADTLALLKRTNASLDVDRFVDDRYIRQACAASGVSYEERLSRHAKVPLAQRDARTGAPIAEPKRAAQLWVDGEAKVRSYENTASALAARQAISAEGKRLRTMFVHDRHTGLKLLAEQAWYAETEDGDLDAFLSRDYAETWARERKGNVRQLDDLEIFHPPPEQRPAAP
>NC_021658.1|WP_020736077.1|5852074_5856352_+|DNA-topoisomerase-3
MIAVVAEKPAVARDIAAVLGASRRAEGFLEGGGYVVTWAVGHLVAIAEPHQIDPAWKRWRLDLLPMLPARFPLVVLPGTRAQFEIVRKILGRRDVERVICATDAGREGELIFRYIYEAAGCKKPVDRLWISSLTPDAIRDGLRRLRDARGYDGLADAARGRSRADWLVGMNLSRAYSLVFDQDLSVGRVQTPTLSVVVERELAIRRFVPEPYLEVVATFCPLREGGEGAADASYKGTYFRDQPLASDPRDPRAPAGPAGEGEKAETAPSRRRLPPDGEEARRIIERARRGEARVEAVRSESRRLPPPLLYDLTELQRHANRLYGFSAQRTLEVAQALYERRKLISYPRTDSRHLSTEVAATLGAVVQAIEGAYQGMLAPGTGTRPLGKRFVDDGKIGDHHAIIPTGARASRAELSPDEQKIFDLVCRRLLSAWHEDHVTAITTVITAITTRARGEGAGAPIVDRYHSAGSVVEKVGWKVLDIGFGKPPARPRKKGESDVKGDAKGGEGREADEGEGERETADQLLPPGLARGQVQLVLDAQALAKKTRPPPRFTEATLLTAMETAGSSLDEKELSEAMKDSGLGTPATRAAIIETLLRREYLVRKGKLLHATDKGIGLIEVVHADVKSPAMTGAWEAKLARMARGGGDLASFMAGIESYVRHVVEEVSAGRRPAGGAAPRPEERSSPFPERGERRGLGSGRGAAPAAPEARGDREAPRATPRRAPAGGAAGAPGTASRGAFPAVAAAAASPLPARARAARSSAATRSSAATRAVAAAAAPRPARAAAVESPPARAAAIVESPPRATAGAAPSAARASIPSSPPARRPADLLELLQQCFGFRAFRRYQEAVCRTAAAGSDVLLVMPTGAGKSLCYQLPGIARGGTTLVVSPLIALMEDQTAKLRACGFAAERIHSGRSRPESRKACIDYLDGALDFLFIAPERLRVPGFPELLARRKPVLVAVDEAHCISKWGHDFRPDYRMLGQRLPALRPAPVIALTATATPVVQDDIVEQLGLTSAARFIHGFRRSNLGIELLEVSPGERLARVRALLGQEGRTPAIVYAPTRKEAESLAAGLAEDLPAEAYHAGLAPQVRDRIQAAFLDGSTEVIVATIAFGMGIDKPDVRTVIHAGLPGSLEGYYQEIGRAGRDGLPSRAVLMHSYVDRRMHEFFHERDYPDPAVLQRIEGALSAEPRPREEILGDLGVDPEVADKALEKLWIHGGARVDPDGGVALGEPGWRGPYEAQRRHKLAELAQMARFTESHGCRMLHLVRHFGDQEDTGEPCGLCDVCAPAACAAREFRAPSRDEAQAIARILSALRDGEQPTGRLYREAFAGGSLERRDFEHLLGGLVRAGLVEVREDSFEKAGELITYQRASLTPRGRLGEPPVDVPLAKIPPKVKKRPGAKSSDARRAFFARKAQRKKGRSR
>NC_021658.1|WP_044988501.1|5856757_5858398_-|SBBP-repeat-containing-protein
MRARAQSHVLVSLLGLGLCGSGCALLLGLDEFADRPPDGAGAGGTGGAGGAGGSEGTTPTCTPDASEACYAGPPATRNEGACREGTRTCGADGTWGVCEGEVVPAVERCDAEEDENCDELACIVWAATYEQTGDIHPIGIASDAEGDVFVSAAFYGTITVGNKTFSSADTTDILLLKLSASGDVLWGTKFGDSSADNPWGMAVGPNGNTVLAGQTSSGATDFGDGPIPSGAFVAQLDTQGKHAWSHGMGGGSNGKITAVAIDANDDVIAVGTFNRPIDFGGGPIPPEDGSDIIVAKLDSETGLATAPGCWTRQLGGTGSQGASAVAVDRSNNIFLAGSSSGALDFGGVVKIENSSFVMKLTPSGVTAWVATMGDPASVQAAGITVDAAGRPVVVGYFRDELKVGPHTLTAAGSNDTFIVQFEPDGTVGWVRTFGGDDEQWAGGVALDPAGNILVAGYATSQIDFGDGPFMLNDTQGFLAKLTPDAELVWSRVLGGGVNLEAVATSPEGETLVAGRTKAVDADFGTGPLPWTSDGTLQHLVIAKLGR

Crispr_ID: NC_021658_20

• CRISPR_ID: NC_021658_20
• CRISPR_location: 5884182-5884270
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_20

Consensus_repeat	Method
CTTGCAGCCGCCCTGGCCCTTGCACTCGTTCT	CRISPRCasFinder

spacers of NC_021658_20

>20.1|5884214|25|NC_021658|CRISPRCasFinder
GGCCCGCGCACCCGTGGGTGTCGCT

CRISPR arrays and Neighbor proteins around NC_021658_20

CRISPR arrays

The CRISPR arrays of NC_021658_20

>merge|NC_021658|20|5884182-5884270|CRISPRCasFinder
CTTGCAGCCGCCCTGGCCCTTGCACTCGTTCTGGCCCGCGCACCCGTGGGTGTCGCTCTTGCAGCCGCCCTTGCCCTTGCACTCGTTCT

>NC_021658|20|16|5884182-5884270|CRISPRCasFinder
CTTGCAGCCGCCCTGGCCCTTGCACTCGTTCT	GGCCCGCGCACCCGTGGGTGTCGCT
CTTGCAGCCGCCCTTGCCCTTGCACTCGTTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020736091.1|5876998_5877907_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NC_021658.1|WP_020736090.1|5875490_5876990_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020736100.1|5884700_5885834_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020736102.1|5887528_5888434_-|DMT-family-transporter	unknown	unknown	gnl|CDD|223769
NC_021658.1|WP_080682739.1|5897087_5897936_-|fatty-acid-desaturase	unknown	unknown	gnl|CDD|366126
NC_021658.1|WP_020736104.1|5892322_5892841_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044986008.1|5880961_5881714_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NC_021658.1|WP_020736093.1|5878435_5879821_-|site-2-protease-family-protein	unknown	unknown	gnl|CDD|100082
NC_021658.1|WP_044986009.1|5885814_5886849_+|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NC_021658.1|WP_148314845.1|5882291_5883167_-|putative-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|378264
NC_021658.1|WP_080682219.1|5892935_5895554_-|MMPL-family-transporter	unknown	unknown	gnl|CDD|274598
NC_021658.1|WP_148313740.1|5888430_5889327_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020736096.1|5881850_5882282_-|YjbQ-family-protein	unknown	unknown	gnl|CDD|223509
NC_021658.1|WP_020736107.1|5896213_5897074_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044988504.1|5883216_5884056_-|DUF692-domain-containing-protein	unknown	unknown	gnl|CDD|377459
NC_021658.1|WP_044986010.1|5890431_5892114_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148313739.1|5879963_5880836_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238141
NC_021658.1|WP_020736101.1|5886845_5887532_+|hypothetical-protein	unknown	unknown	gnl|CDD|238013
NC_021658.1|WP_020736092.1|5877929_5878385_-|dUTP-diphosphatase	unknown	unknown	gnl|CDD|234802
NC_021658.1|WP_020736089.1|5872223_5874965_-|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl|CDD|234570

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020736091.1|5876998_5877907_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	8.94204e-28
NC_021658.1|WP_020736090.1|5875490_5876990_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.13269e-53
NC_021658.1|WP_020736102.1|5887528_5888434_-|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	2.05697e-09
NC_021658.1|WP_080682739.1|5897087_5897936_-|fatty-acid-desaturase	gnl|CDD|366126	pfam00487, FA_desaturase, Fatty acid desaturase.	3.12502e-13
NC_021658.1|WP_044986008.1|5880961_5881714_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	5.91413e-55
NC_021658.1|WP_020736093.1|5878435_5879821_-|site-2-protease-family-protein	gnl|CDD|100082	cd06161, S2P-M50_SpoIVFB, SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. SpoIVFB (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) is one of 4 proteins involved in endospore formation; the others are SpoIVFA (sporulation protein, stage IV cell wall formation, F locus, promoter-proximal A), BofA (bypass-of-forespore A), and SpoIVB (sporulation protein, stage IV cell wall formation, B locus). SpoIVFB is negatively regulated by SpoIVFA and BofA and activated by SpoIVB. It is thought that SpoIVFB, SpoIVFA, and BofA are located in the mother-cell membrane that surrounds the forespore and that SpoIVB is secreted from the forespore into the space between the two where it activates SpoIVFB.	1.277e-33
NC_021658.1|WP_044986009.1|5885814_5886849_+|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.000865126
NC_021658.1|WP_148314845.1|5882291_5883167_-|putative-DNA-binding-domain-containing-protein	gnl|CDD|378264	pfam09836, DUF2063, Putative DNA-binding domain. This family represents the N-terminal part of a Neisseria protein, UniProtKB:Q5F5I0, Structure 3dee. It runs from residues 31-117 as a helical bundle with 4 main helices. \From genomic context and the fold of the C-terminal part, it is suggested that this protein is involved in transcriptional regulation.	1.67934e-12
NC_021658.1|WP_080682219.1|5892935_5895554_-|MMPL-family-transporter	gnl|CDD|274598	TIGR03480, HpnN, hopanoid biosynthesis associated RND transporter like protein HpnN. The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.	7.76584e-40
NC_021658.1|WP_020736096.1|5881850_5882282_-|YjbQ-family-protein	gnl|CDD|223509	COG0432, COG0432, Uncharacterized conserved protein [Function unknown].	1.88135e-59
NC_021658.1|WP_044988504.1|5883216_5884056_-|DUF692-domain-containing-protein	gnl|CDD|377459	pfam05114, DUF692, Protein of unknown function (DUF692). This family consists of several uncharacterized bacterial proteins.	3.47893e-153
NC_021658.1|WP_148313739.1|5879963_5880836_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238141	cd00229, SGNH_hydrolase, SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid.	2.63017e-10
NC_021658.1|WP_020736101.1|5886845_5887532_+|hypothetical-protein	gnl|CDD|238013	cd00056, ENDO3c, endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases.	6.16574e-06
NC_021658.1|WP_020736092.1|5877929_5878385_-|dUTP-diphosphatase	gnl|CDD|234802	PRK00601, dut, dUTP diphosphatase.	1.00653e-79
NC_021658.1|WP_020736089.1|5872223_5874965_-|phosphoenolpyruvate-carboxylase	gnl|CDD|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0

Protein sequences

>NC_021658.1|WP_044988504.1|5883216_5884056_-|DUF692-domain-containing-protein
MRLGLPDLGVGVGLRIPHYRHIFEHRPRVDWFEIISENFMVDGGMPIANLERALASYRLVQHGVSLSIGSTDPLDFDHLRRLKALLRKVGSPWVSDHLCWSGAHGVHLHDLLPLPYTDEAVRHVAARARAVQDFLEVRLALENVSSYLTFTSSRMSEWAFLSAVVEEADCGILLDVNNVYVSSHNHGFDPGAYIDGVPHHRIVQIHLAGHTDQGKYILDTHSDHVADPVWALYRRALGHTGDVSTLIEWDDDLPAFEVLAAEAEKARAIREEVARARAA
>NC_021658.1|WP_148314845.1|5882291_5883167_-|putative-DNA-binding-domain-containing-protein
MFTAGAPLPDDPELAARCREHVAGSSRLTPAEQADIYRRQFWLRHRDALREDFPALAHVLGDDGFDAFCRAYLAAHPPASFTLRDLGRRVADFAAAHEGFPPALRDLARDVARYEQALADRFDGASPPPLDPAKVTGMPEDGWSTARIVLHPLLALMQLRYPAHALRGELRQGRSPAPPAPRPVRLAVFRSDADLTMRCEELEPPAFALLEALGRGVPLVAACEEVAAGVDGAAGVDGAAGIDGAAGIDGAAGACEAASAALGARVGAWFQQWTSWGLIVDVAPGSGAERG
>NC_021658.1|WP_020736096.1|5881850_5882282_-|YjbQ-family-protein
MTTIVQRTLEVRTSGRGFVDITREVARVVASAGVDVGLCAVFLQHTSASLVIQENADPAVLRDLERWMSRLAPEGRDYEHDDEGPDDMPGHLRSAVTRSSEVIPISGGRLALGTWQALYVWEHRSSPHVRRVVVTVTGTTAAA
>NC_021658.1|WP_044986008.1|5880961_5881714_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MSLHTTFMGIFDTARICVPTVVDAMMRRVTLERCDERLDWWARKVLEDADVDLVVRGREHAAGTRPFVVMSNHQSLFDIPVVFRAIPGRLRMIAKKELFHVPVFGQAMKAAGFIRINRSDHVQASASLQVGASMLQDGTRVWIAPEGTRSRTGALLPFKSGGFRMAIETNTPILPVAIDGTRHVLRAKDFVVQQHHRVVVTIMPPIDPAPYGAGGRSRLMRDVRAAIAGALGHDPGLVHRGVGVATSSPA
>NC_021658.1|WP_148313739.1|5879963_5880836_+|SGNH/GDSL-hydrolase-family-protein
MGSGIRVRKWAFAGVAAAGMACGAAPPPGPPAPAPPDAPPSGVTPAPARPPEAAAPSAASAAAVAPPPAAPPEFSVPPNTAVLHIGDSFALAGFAQALRPRMEAHRVRYAVKAETSSYTVTWASRMELLVANYQPDLVIISLGANEVENVNPPAHAGAVRRIVKAIGGRPCVWVSPPLWRKDTGIIDVIRTNSAPCRFFDSDALVPGPLPRKKDKIHPNEVGGARWADAFWAWLMAEHLPPGEGEGGEATKRSPWALRPSPPEEHRSRAQPPESALQQSEPAAARQVERL
>NC_021658.1|WP_020736093.1|5878435_5879821_-|site-2-protease-family-protein
MRMSFRLFGVSVDVQLGFWLSAALLGFGILAREQYQQFLVWVLVVFLSVLMHEFGHAFAIKRHRIEPEITLHFMGGTTTWRSLLPLGRLQHVIISLAGPFAGFLVAGVLHLLLLYVPALYALPIMVLSGMEMLITVNVWWGILNLIPVLPFDGGHVLEHALGPRRGRLTAAISGVAAVLLAIFFLRAGFFFFSLILVMSAFQSLQRFRSEPAASSPAMNRRRAALHEEPVPPETAVLLQRARRGVEDERTDEAMALANEVLAQSPAPPKRAIREAHELIGWSHLLLGDTTRAGESLAQARKHGEPDPALVGAVHLALGELRQARKVLEAAREAGDDRKEVAGPLIRVLVEQGEVARAAAVALDIVEQLSEDDARRMAEIAFAHGAFDWSARLYEAIFRRAGQSEDAYGAARASAKDGNLEGALELLRRAVEAGFSDRARAWSDTALEALRGSGLEAVLPRP
>NC_021658.1|WP_020736092.1|5877929_5878385_-|dUTP-diphosphatase
MRIQVPFLRVGSVEVPPPAYQSEGAVGLDLCAAVDAPVTLAPGERKLLPTGYAVALPDGYEGQVRPRSGLALHHGITVLNSPGTIDPDYRGEIKVVLINLGAEPFTVRRGDRIAQLVICPVALADVVQVSALAPTARGAGGYGSTGVRREP
>NC_021658.1|WP_020736091.1|5876998_5877907_+|LysR-family-transcriptional-regulator
MAARSQDLGDARWDDIRIFLALHRHGSLGQAGVRLGLDTSTVSRRLTALEATLGARLFDRTREGLVPTRVAELVLPAAEAMEAAHRRLARDASGAETDAEGVVRLSVAPGFADSFVVPTLVRLRARHPGIRIELDASVRVLDLTRREADLALRSVRPEGADLVATKLASGRWVAAASAELARDAGRVEAWDALPWITWDRDLASFPPALWLARHAPGAEIALRTSFFRSQITAAELGLGAVLVPEPYLRVHALTPLGFAGALEASAAEWPTDHLWLVGHRALRDVPRVSAVWSFLVEELRSR
>NC_021658.1|WP_020736090.1|5875490_5876990_+|serine/threonine-protein-kinase
MADDVFGIVGTTQGAFKVERVVAEGGFGVVYRAYHEAFRAPVALKCLKVPGTLPEQLRAQFLDKFREEAELLFRLSAAIPAVVRPLHHDVISTAGGVFVPFIALEWLEGSTLASHIAARAAERRPPLSPIEVIRLLTPVARALEAAHRFPGPSGPTCVVHRDLKPANIFLAQTHGAEVVKILDFGIARARDAATVMAGQTATTSGGLSTAFTPAYGAPEQWAPKRFGKTGPWTDVWGLAVTAVEALAGREIIAGDHVAMMGTVLDEKRRPTPRSEGVLVPDALEGAFRRALAVDPRDRFRDLGAFWDEVEQALGLPQSAPPIALPGRGPAPRGARRPSASPAAPRSTRALDLPGAGLTLPASFADEATRELDLPERGGRLPAHSLPTEPVVPLALDWSPPAPPPFARPSYAPSRMPPPMMARAPARPSLSAADLMAMFALPVRLAGAAVVITLLDLGAASLLFDGERIGVGPLRLLHLAVGLVVLGIGIAVFRLFASDR
>NC_021658.1|WP_020736089.1|5872223_5874965_-|phosphoenolpyruvate-carboxylase
MPPRRREVDRPLRKEVRLLGRLLGEVLIEQEGEELFALEERIRTLAIRRRRGPSDGRAHAEAELSKLLASLPHDRIEPVIRAFTVYFRLVNLAEQHHRIRRARAYATDPDARPQRGSLEAAMRALKDAGVPAERVRAALRSLDVTLTLTAHPTEAARRTVLEKLYRIARNLEERDRCKLTPDESAKKLAEIREEITALWQTDEVRRDRPTVGDEVKNVAWYIEEILWDMLPELPAAIGRAFEAAYGEPLDAEFVPLRIHSWVGADMDGNPLVVPAVLEDALFAYRIRGLRRLIRAARELGGALSQSLRHATPPPWLLASIEEDAAAMPEVAAHFGPRTEGEPWRRKLRFIEARLTATLEHAEHGRAEARARYGQGPALEGRAFVRPEEPTLAAPYREPAELERDLALVADSLRAARSGHSGERRARALLSQVRALGFALAELEMRAPAEDARAAAAEVAEGRIEPAQMGPEARRVFEALQRIAAAQRDSGESACRTLILSMTQSENDVLAALACAKAAGLWDEARSCARIDVVPLFESLGALNDSARILRALLAHPSYRPHVLARGVQEVMIGYSDSGKEVGLLAASAALRRVQETLPKIAAEAELPLRVFHGRGESVARGGGPAHQALLALPAGSVGGRYKATEQGEALDHKYARPELAMRTLELMLSGVILHTLGAQPRPPAASELRYAAAFDELAETGRRVYRGLVWEEPKFVEFFTAVTPIDEIARLPLGSRPSKRRAGGLESLRAIPWVFAWTQNRAILPGWYGVGSGLEAMGQRPEGAELLKEMMASWPFFRAVIDNVEMVLAKADMNIFAGYAELAPAAARKAVAPRIIAEYRLTRSWLKRLTGNRRLLDGNPTLQRSISLRNPYVDPLSFLQVELLRASRGGDSDRDRSLLLTLNGIAAGMRNTG
>NC_021658.1|WP_020736100.1|5884700_5885834_+|hypothetical-protein
MSSAARTAGQRAAFPVRRSSLRSARARQSVHGGAPRPWGCARVDRPRPALAALAALAFGAAGCSGAARDEAGTPGGAASGREVSLPAAAAELEAMSGAVLEGREATFRDILADTIAKDAYLCLPAPRDVFHGEAPEGERRIAGMMPHYGLFFGPMSYLVRRRGGAWEVEVRIAVDPPAGGAWLELPDCGLAGALGGAIACRGTPYARSGSTDACPGSGEFTARATPAAIRALLSRWSTEVEGYWNRDARAFGLPVRYDFDFVLGDDARGRALRVDLAVPLSPTCGRTPYFSAMRAGWSLPVLAHEVGHVLGLLDEYEALSGIVGCYPKTPFPGAEISRMGFSMREQTRLLPVHHYLVLRRFFCRAPASMDPYAGAIR
>NC_021658.1|WP_044986009.1|5885814_5886849_+|hypothetical-protein
MPARSAERSARPRAARRRLAAAACGRASLAAAALACAALAGCRSEREGGAADAGAGAVDGGAGAADAGGGAVEAAPPLVGAPPGPRAPVAEPRCPPEMVRVARRFCVDRYEAVLLDREMGLEISAFYPPSRQAAASVERAWSKMRLQLGDAEARRMELPLLPGWQKQREFEPRAVSRRGVLPQGYTTGAQAELACRNAGKRLCTLDEWRTACRGERDEQFPYGPTYADGKCNVFREGHPAAVLHRDVSLGHSDPRLNLVRVAGAPLLRRTGETATCASAWEGDAIADMVGNLDEWIDDPEGTFVGGFYARATREGCMARIASHDFTYFDYSTGVRCCADLREAP
>NC_021658.1|WP_020736101.1|5886845_5887532_+|hypothetical-protein
MTSRTPDASHDEPSPRGSHAGSDAVTSCTDTRPQALAAFAGRIPGLLSANVDEEIHAHMGATISEAVLQAGISYETVVKPRVERLRARHPEAVTTTAFLELMRRIEPSILLGFRGRKPHLVRLTAELLREARVETEADLRLWIELDGSQERLKRLSGIGDKTVDYFKMLCGIRTCAIDVHVLRFIEAAGVEVTGYADAKAVVSRAAELLRVDPATFDRGIWDYMKRRG
>NC_021658.1|WP_020736102.1|5887528_5888434_-|DMT-family-transporter
MKTVALSCFLLNTLLWATFYAVSKEALARIDNFVFSFLEVGSLLPAVVLILCLSWRRERAAFTRALVVRGVKLGSVLALAIFTSTLALKHTTATNTAFFPSLNGIMAALIARGLLKRPIAATTWIAGLVASAGALLMIFEAPVNGAHWRGDLIALLAAFFYTCYIFRVDHDIHQDDSSPWPLFGIEVATMIVLTGLGAAVLGDWSAVHPVFPKDLVVILYIGFGTTLLPTAISIFMQKHVSPVTVAFIYVFEPIWSALLARLYLGEALTLRGYLGGALIISGALMHTWHTVRPTAPALAEA
>NC_021658.1|WP_148313740.1|5888430_5889327_-|hypothetical-protein
MLNKGQIRKSNATVMEEMQAWFRDCLGCVAGRREFLLGRYMITVLDDTDTGTGVLDTYRKFRRHALAYEKVACLLVFNNPELYAGSGCTALDAISYLARQIAPLAHEHPDRLIRGGSVHQRHALKCPVTGALTLFDDFDAIAFCPQADDRDDPLYDPLMAAPYPCINISSDVFGFSMFARDRFLHRYNRDIFGAPADDALRRHLTECAALWQKIAARTIRNYIAMTDTTLCPTYLSEDERYWIANHQDPAFAESEKRAYRHEMPVTYTPQIIDRWMCRMEGGSDGRARAVTTRPGEIL
>NC_021658.1|WP_044986010.1|5890431_5892114_-|hypothetical-protein
MAGFWPLHDRTMPLATARQTLAGAGAAAPGRLAALLDLEPEAIALAAALLRRGVEEATIEASARAARDAGATIARLGVERGLLAPAAGVEESRAPPPLLRAFGADAEVRRSRGEQLSKLRVLLLKGDVLAPDEARWFAVVSRTRPSLADAQVPPFPDRALTGLLEAEANVGEVRPSLELQAAKRASRLGVKARILASEGGRGAVADDDEMERRAIRLLIEEASACYREDRYDGALAVARRALDAAEGRRDLELEIKSRTACARALYMLGDKKAALKESASILALAEDPGRRAEMERADVAWDVANAYRMCAEAGRFLTATPIADLFAALDAGEAYVRRIGRPGWRAGFLKVRSDLLAALGRVEEAIGFAEEGLALMQRDGSGPGPTLACHRWSLGGLLRQQQRFEEAAVHYQAALDAPASSPYDRKVAIQGLARCALARGDAAAGLRHAREAVRLAEGMGDDNLAPALEVLVDAHIAAEDWPSARSAADRMLERARRLRNENRLYFALRAAADVVLGAGDTGRARALLDEAAPLAEALDRQRGGTTGFRDEIEARRKRLA
>NC_021658.1|WP_020736104.1|5892322_5892841_-|hypothetical-protein
MARGFSETLTLVNAPVMLQEEPSAHGPGVRFLCDVYRVRIRDIAEADGLIEQADLERLAYFSGGRGRDFVRLIQALMIKGFDEEAPRATAELVDEVIDAARRRMEEGLYREDFELVARIARDPRHELPNDPRTNDLLRYFRLLPYSNGSEWFYPHPLLTLSKVRVSPAGSDR
>NC_021658.1|WP_080682219.1|5892935_5895554_-|MMPL-family-transporter
MPSPQMPPAAPRPPTSPSHASSPHAAPPSSKGGGLAARLAELQVNRPALPLLATGLLTVIALFLATRLTVLTGFESLLPASRPSVQELDRVAAKTAGVSTLFVVLQGGEGTPTVALQRAADALVPELERLGPPWVGSVEDGVHEAFRYLSPRAGLYVDRDRLTKLRDDIEARYAYEVNKATGALLDEDEPPPEVSARSIEQSLGLNGIDAGRYPDGYYQSKDGKTVVVAIRSKVLGSDFAAGSEAIRRVREVVDRVRPASFDPGITYGLAGDLQTGIAEYAAINEDLTDVGVAGAVLIAAVVFLYYLRVRMLVAMLITIGTGVAWTFGVTQLAIGHLNMATGFLFSIVAGNGINFGIIYMARYLEARRGGASLLEGVRVAHRETWLPTLTAGCAAAAAYGSLLVTEFRGFHDFGLIGSAGMVLCWVATFLALPSVLAVMERLSPLDRASPGLFGRLRRRTQGGIAFGEPFARLAARSPVALTVAGLALAAVGLVATVAYVRADPMEYDLRNLRNDESARAEEIRLGALAEEITGYVGTDGMAILVDRPEQVEPLRAALYARRDAAPEGEKPFKEIYALQDLVPKDQEAKIPLLLEIKERVLRAKKRGLIGDEDWSRIQAVIPPDELAPFGIEDLPAGVARAFTETDGTRGRIVYISPITPESVHDAHYLFRWADAYRETRLPDGSVVRGSGRAVIYADMWAAVIDDVPPAVLFSLAATVLVVLIAFRGGRPAFAVLGALLVGVLWMAGLLVLMGVKLNFLNFIALPLTFGIGVDYAVNIVQRYAREGAGGALTAVRETGGAVILCSLTTTLGYLALVRSQNHAVRSLGVSAVLGELACLFAAVLVLPAALLWRDRRRPKGEESFVAVGRPTT
>NC_021658.1|WP_020736107.1|5896213_5897074_-|hypothetical-protein
MLTRELMGALALAILWVNTLLIAAAALKQLAAVAAALRRLGARLDQRGAALIEARVLRGDGRGGALAGHRIEQVGRAGAGGATREEIVFADSGRGGEIYGGAVVAGGREIAIAPAVEGEVWVSRAEVRAASACPSEARFDEAYQHARKARGFSRTVEARIGPGTPVWLLGDVERAVDGADGADRMRPALVSSVDPRALCRRKLALLSLGVAGVLGGLVGCTALALSRPRFGPLSTAGGALCLAFFLLVQPLGTALRDAASLPSAAPARGRWVRRRARGASARAASS
>NC_021658.1|WP_080682739.1|5897087_5897936_-|fatty-acid-desaturase
MFCAPACRNVVVFAAACCLSFLNAVVIHNHLHQGIFQSRRLNMLFRCVLSFGALYPASANVPSHNLVHHHFDDEGQPDWAAPEHVSFRWNLLNLIHFPNVAGPNTFAGVARWNALAGRPEHVRQYRIETVFAFGLTGALLLVDFWTALFFLVLPQLYGARCILRINLIQHDGCDVRSEWNHSRNFVGRAFNWIMCNNGYHTIHHNRAGLHWSVLAEAHRREVAPRIDPGLNEPSMLGYLLRTYVLRFDRPAPRDVARAERSAPPIALSPRELRRAEAEAASV

Crispr_ID: NC_021658_21

• CRISPR_ID: NC_021658_21
• CRISPR_location: 6104618-6105071
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NC_021658_21

Consensus_repeat	Method
CTTCGGCGACGCCTGCGACAATTGC	CRISPRCasFinder

spacers of NC_021658_21

>21.1|6104643|44|NC_021658|CRISPRCasFinder
CCCACCCTGTTTAACAATTATCAGCAGGACAGAGACAACGACGG
>21.2|6104712|44|NC_021658|CRISPRCasFinder
GCATACAACCCGAATACCGATCAACATAACACGGACGGGGATCT
>21.3|6104781|44|NC_021658|CRISPRCasFinder
CCCAACGCGCGCAACAACGACCAGGACGACGAGGACGACGATAA
>21.4|6104850|44|NC_021658|CRISPRCasFinder
TCAGAAGTCGCCAACCCAGACCAGCTAAATCAAGACGGCGACGG
>21.5|6104919|44|NC_021658|CRISPRCasFinder
CCCAACGTCACCAACGTCGATCAATCCGACAGAGACGGCGATCG
>21.6|6104988|59|NC_021658|CRISPRCasFinder
CCTGCGACGCCGAACGGGACCGACGGCACGAGCCATCAAGGCGACGGTGATGGTGACGG

CRISPR arrays and Neighbor proteins around NC_021658_21

CRISPR arrays

The CRISPR arrays of NC_021658_21

>merge|NC_021658|21|6104618-6105071|CRISPRCasFinder
TCACGGCGACGCCTGCGACAACTGCCCCACCCTGTTTAACAATTATCAGCAGGACAGAGACAACGACGGCATCGGCGACGTCTGCGACAACTGTGCATACAACCCGAATACCGATCAACATAACACGGACGGGGATCTCTTCGGCGACGCCTGCGACAATTGCCCCAACGCGCGCAACAACGACCAGGACGACGAGGACGACGATAACTTCGGCGACGCCTGCGACAACTGCTCAGAAGTCGCCAACCCAGACCAGCTAAATCAAGACGGCGACGGCCTCGGCAACGCTTGCGACAACTGTCCCAACGTCACCAACGTCGATCAATCCGACAGAGACGGCGATCGCATCGGCGACGTTTGCGACAATTGCCCTGCGACGCCGAACGGGACCGACGGCACGAGCCATCAAGGCGACGGTGATGGTGACGGGGTCGGCGATGCCTGCGACAATTGT

>NC_021658|21|17|6104618-6105071|CRISPRCasFinder
TCACGGCGACGCCTGCGACAACTGC	CCCACCCTGTTTAACAATTATCAGCAGGACAGAGACAACGACGG
CATCGGCGACGTCTGCGACAACTGT	GCATACAACCCGAATACCGATCAACATAACACGGACGGGGATCT
CTTCGGCGACGCCTGCGACAATTGC	CCCAACGCGCGCAACAACGACCAGGACGACGAGGACGACGATAA
CTTCGGCGACGCCTGCGACAACTGC	TCAGAAGTCGCCAACCCAGACCAGCTAAATCAAGACGGCGACGG
CCTCGGCAACGCTTGCGACAACTGT	CCCAACGTCACCAACGTCGATCAATCCGACAGAGACGGCGATCG
CATCGGCGACGTTTGCGACAATTGC	CCTGCGACGCCGAACGGGACCGACGGCACGAGCCATCAAGGCGACGGTGATGGTGACGG
GGTCGGCGATGCCTGCGACAATTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020736246.1|6089443_6089851_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350220
NC_021658.1|WP_020736248.1|6092949_6093933_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381326
NC_021658.1|WP_020736259.1|6115486_6116719_-|c-type-cytochrome	unknown	unknown	gnl|CDD|368963
NC_021658.1|WP_020736254.1|6108067_6109489_-|IS701-family-transposase	unknown	unknown	gnl|CDD|379252
NC_021658.1|WP_049949571.1|6091592_6092933_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|237057
NC_021658.1|WP_020736260.1|6116892_6117681_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187346002.1|6094706_6095522_+|hypothetical-protein	unknown	unknown	gnl|CDD|253298
NC_021658.1|WP_148313764.1|6089867_6091466_-|metallophosphoesterase	unknown	unknown	gnl|CDD|277347
NC_021658.1|WP_044986039.1|6111904_6113377_+|hypothetical-protein	unknown	unknown	gnl|CDD|277343
NC_021658.1|WP_148313769.1|6109731_6111618_+|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NC_021658.1|WP_044986040.1|6117703_6119254_-|hypothetical-protein	unknown	unknown	gnl|CDD|240291
NC_021658.1|WP_020736262.1|6119496_6119982_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020736250.1|6097775_6099584_+|PEGA-domain-containing-protein	unknown	unknown	gnl|CDD|285503
NC_021658.1|WP_044986036.1|6087961_6088936_-|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|176191
NC_021658.1|WP_020736251.1|6099642_6100368_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020736253.1|6107175_6107907_+|hypothetical-protein	unknown	unknown	gnl|CDD|237537
NC_021658.1|WP_020736249.1|6095917_6097738_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020736245.1|6089207_6089447_+|hypothetical-protein	unknown	unknown	gnl|CDD|226603
NC_021658.1|WP_020736257.1|6113499_6114273_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NC_021658.1|WP_020736258.1|6114318_6115380_-|EfeM/EfeO-family-lipoprotein	unknown	unknown	gnl|CDD|271139

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020736246.1|6089443_6089851_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350220	cd09872, PIN_Sll0205-like, VapC-like PIN domain of Sll0205 protein and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Synechocystis sp. (strain PCC 6803) Sll0205 protein and other uncharacterized homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.76918e-52
NC_021658.1|WP_020736248.1|6092949_6093933_-|aldo/keto-reductase	gnl|CDD|381326	cd19100, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	1.49832e-94
NC_021658.1|WP_020736259.1|6115486_6116719_-|c-type-cytochrome	gnl|CDD|368963	pfam06537, DHOR, Di-haem oxidoreductase, putative peroxidase. DHOR is a family of di-haem oxidoredictases. It carries the two characteristic Cys-X-Y-Cys-His haem-binding motifs. The C-terminal high-potential site functions as an electron transfer centre, and the N-terminal low-potential site corresponds to the peroxidatic centre. Its probable function is as a peroxidase.	7.83689e-64
NC_021658.1|WP_049949571.1|6091592_6092933_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	8.90233e-09
NC_021658.1|WP_020736254.1|6108067_6109489_-|IS701-family-transposase	gnl|CDD|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.54793e-54
NC_021658.1|WP_148313764.1|6089867_6091466_-|metallophosphoesterase	gnl|CDD|277347	cd07402, MPP_GpdQ, Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain. GpdQ (glycerophosphodiesterase Q, also known as Rv0805 in Mycobacterium tuberculosis) is a binuclear metallophosphoesterase from Enterobacter aerogenes that catalyzes the hydrolysis of mono-, di-, and triester substrates, including some organophosphate pesticides and products of the degradation of nerve agents. The GpdQ homolog, Rv0805, has 2',3'-cyclic nucleotide phosphodiesterase activity. GpdQ and Rv0805 belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	5.74208e-13
NC_021658.1|WP_020736245.1|6089207_6089447_+|hypothetical-protein	gnl|CDD|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	9.35149e-11
NC_021658.1|WP_044986039.1|6111904_6113377_+|hypothetical-protein	gnl|CDD|277343	cd07398, MPP_YbbF-LpxH, Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain. YbbF/LpxH is an Escherichia coli UDP-2,3-diacylglucosamine hydrolase thought to catalyze the fourth step of lipid A biosynthesis, in which a precursor UDP-2,3-diacylglucosamine is hydrolyzed to yield 2,3-diacylglucosamine 1-phosphate and UMP. YbbF belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	0.000676043
NC_021658.1|WP_148313769.1|6109731_6111618_+|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	1.41381e-32
NC_021658.1|WP_044986040.1|6117703_6119254_-|hypothetical-protein	gnl|CDD|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	5.26451e-05
NC_021658.1|WP_020736250.1|6097775_6099584_+|PEGA-domain-containing-protein	gnl|CDD|285503	pfam08308, PEGA, PEGA domain. This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteristic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	5.30542e-10
NC_021658.1|WP_044986036.1|6087961_6088936_-|NADP-dependent-oxidoreductase	gnl|CDD|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	3.99569e-83
NC_021658.1|WP_020736253.1|6107175_6107907_+|hypothetical-protein	gnl|CDD|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	4.3102e-07
NC_021658.1|WP_020736249.1|6095917_6097738_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.51655e-94
NC_021658.1|WP_187346002.1|6094706_6095522_+|hypothetical-protein	gnl|CDD|253298	pfam05642, Sporozoite_P67, Sporozoite P67 surface antigen. This family consists of several Theileria P67 surface antigens. A stage specific surface antigen of Theileria parva, p67, is the basis for the development of an anti-sporozoite vaccine for the control of East Coast fever (ECF) in cattle. The antigen has been shown to contain five distinct linear peptide sequences recognized by sporozoite-neutralising murine monoclonal antibodies.	1.06132e-05
NC_021658.1|WP_020736257.1|6113499_6114273_+|serine/threonine-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	7.54052e-66
NC_021658.1|WP_020736258.1|6114318_6115380_-|EfeM/EfeO-family-lipoprotein	gnl|CDD|271139	cd14656, Imelysin-like_EfeO, EfeO is a component of the EfeUOB operon. This family includes the EfeO domain, an essential component of the EfeUOB operon which is highly conserved in bacteria. However, its biochemical function is unknown. EfeO contains an N-terminal cupredoxin (CUP)-like domain and C-terminal imelysin-like domain that may bind iron. Algp7, a member of EfeO family protein from Sphingomonas sp. A1, is found to bind alginate at neutral pH, but does not contain the CUP domain, thus having a role that does not seem to be related to iron uptake. Some members of this family are fused to an N-terminal putative EfeU ion permease domain. The imelysin-like domain of this family also contains the GxHxxE sequence motif and a highly conserved functional site, suggesting a similar role to other imelysin family proteins containing the same motif.	7.87947e-25

Protein sequences

>NC_021658.1|WP_020736251.1|6099642_6100368_-|hypothetical-protein
MVNNVGRCTPVGTDLNHEAPHPNEGGTFRREACPGEGACAGYCGGHSDAMCRFPADGAVARTSVCSCPDEGCAIGPATLTRFFCDGDGREKAPVVERCGGENGGFKCEDESACKTSCASDADCIKDFICSDGVCIDLEEVGPRCDGEHTLRAAGGDTDCTPYRCPPGGGACASPCRSVADCVDGMVCDLANQCVPQLDPSQVPSCSCGVVGASTERAPALASVLLGAAAALAGLRRRQRRP
>NC_021658.1|WP_020736250.1|6097775_6099584_+|PEGA-domain-containing-protein
MDLRARRGGSCPLSLAWRPRPARRLRALSAALAVAVGAGPALAQPAPAAAEGAAPAEEAPVSETTRQVARLHFEKGLALLREEAWGPALAEFLLSRKLYPTRAATNNAAIALRKLQRYDEALEMFETFLRDFTMSAAERAVAQREIAELRALVGTLDITNAEPGASIVVSGEERGQYPPVKPIRVAAGAHVVRVFKEGYEPVEVRVYVAGGQTVTVNAKLRRLVRSGRLRVVERAGKTVDVLVDNVVVGQTPWIGTLSVGDHMVALRGEGKLGTQPTAAPVKPQELTTLSLLAEDLDASLRVDPTPPGASVWINSVNVGNGVWLGRLKAGAHRVEVKADGFVSEARTVTLQKGQRQGLSLALERDEDAEIWRKPPKITLEASASFLVAPTFGGDVASACGSGCSSAIGLGGLGTIHGGYELGSGLGVGIELGGIVAAQQLEERAAELRPIGYRDPLGGAASDALRLGGFLAGATFGYHLGEQYPALLRLGAGVLVGEVRDERTGRFRTTQGAWFNTYPVVDFASATYFYVDPEARLGVRLGERWELSASVKLLLLIGLSKPSWDRTIELAASTDGIGTYGQESLMGDVVLMIAPGASLRYQF
>NC_021658.1|WP_020736249.1|6095917_6097738_+|serine/threonine-protein-kinase
MIGTIIDGKYQIRKLLGEGAMGSVYEAEHTGTGRRCAVKVISSADLTRDPKVVSRFQREARAAGAIDTQHITQVLDAGVDRDSKLPFLAMEYLAGEDVHQLIKRVGPLAPDLALRIVAQSCLGLQKAHEASVVHRDIKPHNLFLSRRDAGEILVKLLDFGIAKVKMDRANETEGADLTRTGNLIGSPLYMSPEQARGQKEIDHRTDIWSLGAVLYQALTGRTPYHHITALGELIIAICSDPPPPVQDFAPWVPPEVAAIVHRCLLQAPGQRYQSAQEMFGAIRPLLPYGWGIHESMLVPLPDAVRRQSAPRLSMNGNAPPANQSGAYAAASPANQSGGYHALAASPANQSGAYAAASPANQSGGYPAVPHEHRGGGYPSFAPPPSPSGPHGAIAPAANHAGAATTGALTQSHRGTQPGASRVPVVAGAALLAAGIAAGVYFVSRGSPEPAAPPAASATPEVLPTAAATPTPTPAPAPPPAATGTSEAAAAEPQPRRVQVVILPPDASVEVEGAGATTRNGILEITGPLGSEHRVRVFKGANETVTDVIVTTSGARPLKIELPPTPVKGAPVLPAKSASAAPPAAPAPAPAPTTYKGIINDTEEFGK
>NC_021658.1|WP_187346002.1|6094706_6095522_+|hypothetical-protein
MLSIHGKVLGLAVVMAALGTGCAVDSVSDVELDEAGLDEVEQVDSTAEALEGDEATRGGFQQAPSKAPLGPSKGGLGQQAPIGLQGPADLGQAPVGVQGPAGPGLQAPIGQVGQAPIGQAPIGQGPMGVPGVGAPGLPGVGLPGVGVPGLGLGMPGLGFGAGGFGALGSRFGGFGGFGCCPINIINNNIFIDDRFRDFCHFPPHCFDRFDHFDGFNGFNNFCGFPHNRFDRFDDCRPGFFPNRFCHCFPHRHCGGGHNNNWGWGGSSGSGC
>NC_021658.1|WP_020736248.1|6092949_6093933_-|aldo/keto-reductase
MSNEPNETEGADASRRGVLRAAATTAAAIATGAAGGAPSAAPEAPRGAAAAPPRTLGRTGAQVEAVSLGGEGILRTTGRHREAVPVILEALRLGVRYCDTAPAYQQSQDYYGEAFRAAGPSAREQVFLASKTHARDRDGALRLLDDSLRRLGTDHLDLWQLHDLRELDELDAIFGKGGAIEAVEQARADGRVRHVGITGHHDPQILVEAMRRYPVDTVLCAINPADPARLPFLTTVVEEARRRGVGVIGMKIMAAGRLLQDRAATPSELIRYAASHADTVIIGCSSIAEVRENLGARSLPFPMPPAERAALEARVAPRAGRYDAFKA
>NC_021658.1|WP_049949571.1|6091592_6092933_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MSCPETPHDPASAPRPPAPSDPPPALSTGPRAAPAPSATARGARGGGSIAALAAAGALGAGSSCPPTAAVGTAAHANAPAARAAAPLIAGALQERALAASAAPPERAAPAGDDEDVEPGTLEEQRLRLFARMRRELALSDEAMREVEAIFAASPVLGQGNPALSRHPMSRSECRRARELAGVAPAREPACGAPGMVPLFDPTRGQTAESAPVCIDQLEFPNIPCEYPVVHVRAREAALLCRAVGKRICDAHEWEGACAGALREPDVEYEWERPRDEASWHHNLLREKVWSYGPEKNHALCGTGSARTPGCPGGGWDRCGSNTYPAGAFPACRSRLGVFDLHGNVAEHMSLPILPDELARRGDRGFTEMKGSWFAFSSMEVHADDCRWRAPDWHGTRIMSKGSHANYHLGLRCCKDVAPTAAPSGSTAAAPGTAEGEGAAVAAVKKR
>NC_021658.1|WP_148313764.1|6089867_6091466_-|metallophosphoesterase
MVRRAALRILYLALLPVLVLSALIVAPAVVVSRIASRGRVWRPETWKKISYGSRYFRSSFRGRLGEVVDVIDVVRDRLILLFLVLAAVCLAGGFLAHLLEIGVPSWLTAWLDGSILSSFGPHLAWFPAGGSVSFGGGAAFVLAGCIALALLALGLSLYAWLAFALGEATRVILRYGGAATLFPDPGDAIPGGRLVLCQLSDLHITAGGREPYEIEEGSAAWPEGVARPDTAELTGRLRRLVAEIAAMKPPLVALTGDMTDLGEEAQWAELEAALSGIPASSQVLMVPGNHDIAINVGTSPDPYLKKRAEREQRFIEVLTRVERGPFQPRLHIPARKRARRRLRAIAGLYPRRLDLEGGIRIFGLNSNRYRSRFVGSNAIGQIGGGQLRRLARALRRGSGPVIVLLHHHVARLAGPISLNDTFMIAMDGPRLLEMLAAYQQKNPKKNSALVLHGHKHLAFFGHYRSKSGGRVSVYAHPSSTLGHETDGHLDGVARFAAIRLTDEGIWRVETHPLRPARAAVEAPPAAAEAAVS
>NC_021658.1|WP_020736246.1|6089443_6089851_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MKILLDTHVFLWFITGDARLSEAMRHGIREPENEAYLSVVSVWETMVKHQLGKLPLPAPPESYIPAQRERHRIESLAVDEASVACLARLPPLHRDPFDRMLICQAIRHDLVLATADAAMRGYTIDVPGTPWQRPR
>NC_021658.1|WP_020736245.1|6089207_6089447_+|hypothetical-protein
MTTISIEEIQQDLRGYLRRVAAGETLIIIESNQPVAEIRPVATPARGSRPFGLCAGEFAVPDDFDAPLPEDLLDSFEGR
>NC_021658.1|WP_044986036.1|6087961_6088936_-|NADP-dependent-oxidoreductase
MEQSTPSTMRAIAIDRFGGPDTLALRTLPVPTLAPDEVLIRVEIAGVGEWDPFEREGGYAEMLGRSPQFPYVLGSEGAGTVVAVGERVRRFRAGDRVYALGFLNPKGGFYAEYAAVRADLVASIPGALTLEQAAVMGGVATTALRGLDDTLRLKQGESVVIFGASGGVGHTAVQLAKRMGARVLAAASGGDGVALVERLGADAAVDGRKGDVLAAARAFAPDGLDAALLVAGGEAAQRALLAVRDGGRAAYPNGVQPAPEARPAVQLASYNGEPDADIIERLNRLVASGPFHVEIARRFPLAEAAEAHLALGRHHLGKLALQVH
>NC_021658.1|WP_020736253.1|6107175_6107907_+|hypothetical-protein
MQASRWFVVWMAVGAFGMAGTAVGCSDTGDNTSASPTSTTTGSGGAGGTGSGGAGGTGSGGAGGTGSGGAGGTGSGGAGGTGSGGAGGTGSGGAGGTGSGGAGGTGSGGAGGTGSGGAGGTGSGGSGTGGAGGAVDQHFTLSVYGAGYVPAYDAGTTVYVDVVAVDETEAILSASDTIAANGTFSVTGQLLGGKAYTMHWYVDLDTNGICRNEDDHVWTQDIPVVTADVKRDVGPSTAFGTCP
>NC_021658.1|WP_020736254.1|6108067_6109489_-|IS701-family-transposase
MSPGASELPAAAAWDALAADFEAFHARFAGLFARSEPREQAIKYVRSLMGPAARRNGWQLAEAIGDPTPDRVQRLLYSADWSADAARDLLMDFTIEQFGDPQGIGVLDETGFLKKGTKSVGVARQYSGTAGKIENCQIGVFLSYTSPRGHVILDRRLYLPESWCSDPARRQEAHVPEDVAFQTKPQLAMQMLHDAWQRGVPMAWVTGDEVYGDDPVLRDGIAAQGHRYVLAVISSAPVWPQRPAVAEPPTEREHPRGPLRTRTRLAPGAPHASTVAKVVAQWSPKQWHRLAVHQGEKGPIEYDWARARVVDSRRRLPTDEIWLLARRSVSNPSEVAYYLSNAGAATPLATLAHVASTRYTIEQCFEEAKDDVGLDHYEVRTWPSWHRYITLGMMALAWLAFVRAKLPAEGAFPYAPAMNPELVPKAARPGPGKNAERVQKAALDTLGKKSPPRSKKATLRRRWRPGAFPKSVA
>NC_021658.1|WP_148313769.1|6109731_6111618_+|OmpA-family-protein
MRMLPPASRPRYRGQPMRSSSIAAAASAAVLVTLASAARGQSSGGFSLDRFEPAPAGDAFFGVPSPAAPGHLAPRVYAMVDYAHRPIHSSGDDSIDLVSSQAFLRLDASLALWDRLLLSIDAPLAIAQGGDDPRIAGVEFTELRAPELGDLRFGARVRLLGEDAGPLQLGLGGYLFAPTGTPAQYTGDAEARGALHASLGGRVDLAHGALGFLWNASGGVELGGGPNRPQQLTFGGAAGLLIGGDLLQLGAEAYGAAPLGEELLLSSAPVRPEEAGVNAELLLGAKLRVLGGLTFGAAVGPGLTNAIGTPPVRAVGVIGWTPLPEPAPERAEAAAALGDKDDDGIDDHIDACPDVKGDPSPDPAKDGCPPADRDGDAVLDIDDACPSTPGARSADATQNGCPDDSDDDGFHDGIDACPSVRGGPSDDPKLVGCPSDADGDGIADASDACPKVKGPASQNPKQNGCPDDPDGDGVRGAADACPNERGLSDPDPRQNGCPRFVRVNADEITTSKPVQFVVYGKTRAQTVDPVSDEILYEVRDAIQQNPDIELVEVQGHTDDSGTEEYNQRLSQERAEAVLSWLVAAGVPREKLVARGYGFEQPLGDNRVKTGRQKNRRVQFVIIKRKGRQ
>NC_021658.1|WP_044986039.1|6111904_6113377_+|hypothetical-protein
MRYRQAPYSPDSEVAAMLDALRDEMKQGTARGAGRHELTLVLNGDVFDLDAPRVIDRKSVFHDLPRSAEHAVPAMKAILADHPVFIEALGRVVADGHTVVFISGNHDVQLTLPEVRDLVRSRVVEAALAALDGAPRPGSSSPTPEAGRARAALGARVVFRAWFHKTPDGIIVEHGNQYDAYCSYRYPMVPFGRKPGEIQPTMGSLVCRLLVSRMGYFNPHVDSSFMLSAFGYLAHWARYYLFSRRSLAGAWALGALRTVVELVRRREPERRARLRECLAAAAQETGAPLRAVARHARLFAPPAEDRLGLVARELWLDRAALALLAVAVALVWLLLAPIWLAPAALVAPVGLVVYERLVPKLPLEATWQRVSRAARQVARAHRARAVVFGHTHTPEGSWEGGLFFGNTGSWSAAFEDIACTKPVFAARPLVWLRSEPGAGSSARLAGGLVTWKNGRFEARTASVPPPAEQLREPHGAPPPLRSPATAALRT
>NC_021658.1|WP_020736257.1|6113499_6114273_+|serine/threonine-protein-phosphatase
MNSPLRIEAAGESHVGRQREHNEDSFAVDLDLGLFVVADGIGGAAGGEIASRMAVDIVQACCKEGEGEITQPTGYDEAAGPLELRLVSSIWRANERIFEVGQRDPRFYGMGTTFAGVYVDATSACIAHVGDSRVYRYRERRLERLTEDHSLWNEHLHSGEQLPDDVDPLLARNVVTRALGMGKTVDVATRIERPEAGDLLLICSDGLSGPVPEPEIAALLALGDDLATTARSLVDRANQHGGPDNVTCVLIRWTPAA
>NC_021658.1|WP_020736258.1|6114318_6115380_-|EfeM/EfeO-family-lipoprotein
MHIPACLRSGLAIAAAALSLPACGSDNETLYTDADYERRAVLEVKAFIQDNLDEFAAATAALQAAAPEPDEDGWSASSDKAAVDAMKAAWKEARQSYERVEGAIAVVFPDLDYSTDARYDAFIEVAADDDLFDDEGVTGVHGVERILWADEIPEPVLAFESALTNYKAAAFPATEAEAAAFKGELCERLKADAEKMKADFEGLALDAPSAYRGVISSILEQVEKTSKAATGEEESRYAQYTLADMRANVAAGEQTYAAFQPWLLTKGAEGAEVDKAVLAGFDRLSSAYDAIEGDALPPLPDEWSEEAPTEEQLATPFGELFSLVERESDDATPGTLAYDMTRSADLLGIPSLP
>NC_021658.1|WP_020736259.1|6115486_6116719_-|c-type-cytochrome
MSRFASVLALPVLFIVGCGGEPAPADPLLGLQLIGDDLSDIPLHGASAEQVARFKEGDALFDFVFRERDGLGPLYIRSACAGCHEGAARGPGAVQKMVLVEADGVTPAVDQAALPYGHTMRPYGVAGATTLARPELEGTIKLSQRLGPPVFGRGYMEAVDDAEIERVAAEQAARGDAIRGRINRVVFHSKKNADESFHTFAEGDENLIGRFGFKARVATLDDFTADAYQGDMGITSPLRPDELPNPDGLTDDAKPGEDVVLDTVNAVADYMRLLEIPRRAPADERGQALFAEVDCAACHVPSLRTRADYPIAQLADIDAPVYTDFLLHDLGPDLADGLADESASSVSWRTAPLIGMRHSTSYLHDGRARTIEQAILLHDGPASEAADSVAAFRALSREDREALIDFVRSL
>NC_021658.1|WP_020736260.1|6116892_6117681_+|hypothetical-protein
MTQRDDERRAASMALRDGLREIAWLDDRRAAHLALNAGWLRYMGPGYGNDVCSMCGALLERGTAYMHCAPCLATRGIDEQALLRACAGAMAGDWPFQDRRPDGRRWAHALIAFWRNHVDPMESRAVPYRNNTLESAFHYMKRRLAEAGVAEIWTLPEESQRGLDPAMVVRARGGALAIGVATQRRIATAEDGAPGGHVALFDEFLRLAGEREGFLVVEKLSRRARRDAPVRESAVTTAEGRRVTQLRCMQEDRSWPAPPAPA
>NC_021658.1|WP_044986040.1|6117703_6119254_-|hypothetical-protein
MGIQFKAHALVLLGFTSAAAATASGCNIGNGDYVTIPIDDGPSDDDCTPSKAEGKIASSCGLWVSRTGHDGNAGTSGAPLKTLSKAIELAFSKGKRIYVCAEEFDEAVLVPSGHRIFGGLDCRDDWRWIGDKKKTTLTAPEGETPLKFHGGSGASTVFVEDLHVIARSILPTHTELAGRSSIAANTSGIPVDFTRCILEAGDGAPGKEGESFASDPAEAGQPGNVGNAACTSASVLGGAPVFNTCGTPDDREDDSRSGSGGVGSVLSGSDGGDGDPRDAENGGRGESSSRACTPGDAGADGADGRPGAGAVGFGDVILDGYTGPLAGNGTPGKPGQGGGGGGGAKGGAGALMCPFESTAGGAAGGSGGAGGCGGLGGNGGGAGGASIAVFAGSATVFFNDVVLRTGRGGDGGDGGRGQEGGEGGEGGPGGILGEATGLNAACSGGPGGRGGRGGHGGGGLGGHSIAVAYAVRAPSLSNTTIELGEAGLGGRGGSARYNGQDGVAAEIYDIEQAFRQ
>NC_021658.1|WP_020736262.1|6119496_6119982_+|hypothetical-protein
MSANLKDLVREVLDAGGGEPLEGGRFLPLVTLESGARVGLDSAGGWVFAPEGGGAAQTFAPERGRVFFEVLESRRDDFDASIEAAAKAAGLPPEEVAFSFPAVDVVRAVLARGLPSMTRLALAWLRLTEARALRADIVAVSRDPTMPVPIRNLAERLTVPE

Crispr_ID: NC_021658_22

• CRISPR_ID: NC_021658_22
• CRISPR_location: 6287268-6287372
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_22

Consensus_repeat	Method
GGCTGTTTCAGGTCAGCCCTCCTTTCGCG	CRISPRCasFinder

spacers of NC_021658_22

>22.1|6287297|47|NC_021658|CRISPRCasFinder
CCGGGCATAGAGCCTCACGGCATCATCGCAGCGGGCCCTGGAAGAGT

CRISPR arrays and Neighbor proteins around NC_021658_22

CRISPR arrays

The CRISPR arrays of NC_021658_22

>merge|NC_021658|22|6287268-6287372|CRISPRCasFinder
GGCTGTTTCAGGTCAGCCCTCCTTTCGCGCCGGGCATAGAGCCTCACGGCATCATCGCAGCGGGCCCTGGAAGAGTGGCTGTTTCAGGTCAGCCATCCTTTCGCG

>NC_021658|22|18|6287268-6287372|CRISPRCasFinder
GGCTGTTTCAGGTCAGCCCTCCTTTCGCG	CCGGGCATAGAGCCTCACGGCATCATCGCAGCGGGCCCTGGAAGAGT
GGCTGTTTCAGGTCAGCCATCCTTTCGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020736380.1|6289966_6291715_+|cation:proton-antiporter	unknown	unknown	gnl|CDD|182633
NC_021658.1|WP_020736375.1|6283835_6284543_+|RtcB-family-protein	unknown	unknown	gnl|CDD|376465
NC_021658.1|WP_020736373.1|6282457_6283162_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044986061.1|6280776_6282150_+|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl|CDD|366662
NC_021658.1|WP_049949580.1|6277979_6279653_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_044986062.1|6294752_6295493_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213228
NC_021658.1|WP_063752011.1|6292978_6293854_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|376777
NC_021658.1|WP_020736370.1|6276111_6276534_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_129576083.1|6275619_6275937_+|PEGA-domain-containing-protein	unknown	unknown	gnl|CDD|285503
NC_021658.1|WP_020736371.1|6276530_6277559_+|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|224511
NC_021658.1|WP_020736386.1|6295654_6296677_+|MCE-family-protein	unknown	unknown	gnl|CDD|224380
NC_021658.1|WP_020736384.1|6293869_6294727_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|376777
NC_021658.1|WP_020736377.1|6287533_6288166_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NC_021658.1|WP_044988573.1|6284523_6287136_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173814
NC_021658.1|WP_044986060.1|6279720_6280704_+|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NC_021658.1|WP_020736374.1|6283455_6283839_+|hypothetical-protein	unknown	unknown	gnl|CDD|234787
NC_021658.1|WP_020736378.1|6288162_6289125_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187545
NC_021658.1|WP_020736387.1|6296795_6297011_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit	unknown	unknown	gnl|CDD|133459
NC_021658.1|WP_020736379.1|6289175_6289850_+|glutathione-S-transferase-family-protein	unknown	unknown	gnl|CDD|198303
NC_021658.1|WP_020736381.1|6291737_6292676_-|DMT-family-transporter	unknown	unknown	gnl|CDD|273359

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020736380.1|6289966_6291715_+|cation:proton-antiporter	gnl|CDD|182633	PRK10669, PRK10669, putative cation:proton antiport protein; Provisional.	7.16503e-154
NC_021658.1|WP_020736375.1|6283835_6284543_+|RtcB-family-protein	gnl|CDD|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	1.01327e-33
NC_021658.1|WP_020736378.1|6288162_6289125_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187545	cd05234, UDP_G4E_2_SDR_e, UDP-glucose 4 epimerase, subgroup 2, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup is comprised of archaeal and bacterial proteins, and has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.73377e-128
NC_021658.1|WP_044986061.1|6280776_6282150_+|3-deoxy-7-phosphoheptulonate-synthase	gnl|CDD|366662	pfam01474, DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyze the first step of the shikimate pathway.	0
NC_021658.1|WP_049949580.1|6277979_6279653_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.17358e-108
NC_021658.1|WP_044986062.1|6294752_6295493_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213228	cd03261, ABC_Org_Solvent_Resistant, ATP-binding cassette transport system involved in resistant to organic solvents. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	3.46053e-104
NC_021658.1|WP_063752011.1|6292978_6293854_+|ABC-transporter-permease	gnl|CDD|376777	pfam02405, MlaE, Permease MlaE. MlaE is a permease which in E. coli is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. In NMB1965 it is involved in L-glutamate import into the cell. In Arabidopsis thaliana TGD1 it is involved in lipid transfer within the cell.	1.88997e-67
NC_021658.1|WP_129576083.1|6275619_6275937_+|PEGA-domain-containing-protein	gnl|CDD|285503	pfam08308, PEGA, PEGA domain. This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteristic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	1.39011e-05
NC_021658.1|WP_020736371.1|6276530_6277559_+|RNA-polymerase-sigma-factor	gnl|CDD|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	5.27995e-18
NC_021658.1|WP_020736386.1|6295654_6296677_+|MCE-family-protein	gnl|CDD|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	1.03903e-23
NC_021658.1|WP_020736384.1|6293869_6294727_+|ABC-transporter-permease	gnl|CDD|376777	pfam02405, MlaE, Permease MlaE. MlaE is a permease which in E. coli is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. In NMB1965 it is involved in L-glutamate import into the cell. In Arabidopsis thaliana TGD1 it is involved in lipid transfer within the cell.	3.08808e-56
NC_021658.1|WP_020736377.1|6287533_6288166_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.31653e-13
NC_021658.1|WP_044988573.1|6284523_6287136_-|S8-family-serine-peptidase	gnl|CDD|173814	cd07489, Peptidases_S8_5, Peptidase S8 family domain, uncharacterized subfamily 5. gap in seq This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.19175e-80
NC_021658.1|WP_044986060.1|6279720_6280704_+|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	3.39722e-05
NC_021658.1|WP_020736374.1|6283455_6283839_+|hypothetical-protein	gnl|CDD|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	4.53132e-06
NC_021658.1|WP_020736387.1|6296795_6297011_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit	gnl|CDD|133459	cd06850, biotinyl_domain, The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, oxaloacetate decarboxylase, methylmalonyl-CoA decarboxylase, transcarboxylase and urea amidolyase. This domain functions in transferring CO2 from one subsite to another, allowing carboxylation, decarboxylation, or transcarboxylation. During this process, biotin is covalently attached to a specific lysine.	3.06731e-22
NC_021658.1|WP_020736379.1|6289175_6289850_+|glutathione-S-transferase-family-protein	gnl|CDD|198303	cd03194, GST_C_3, C-terminal, alpha helical domain of an unknown subfamily 3 of Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, unknown subfamily 3; composed of uncharacterized proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain.	1.90238e-58
NC_021658.1|WP_020736381.1|6291737_6292676_-|DMT-family-transporter	gnl|CDD|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.22674e-11

Protein sequences

>NC_021658.1|WP_044988573.1|6284523_6287136_-|S8-family-serine-peptidase
MKYGVRWFGLACLHIALSACSGELGVEGAGQNNAPPDGAAAGEAAFAPEEPTELWFVELERAPAATSGGRARAKGMADEERALFRRAAEERGLRYALRFSYEELWNGLSVRVARGGSAALAEMPGVKAVYPVVPVELDVARAATAVDPDLAVASDMSGADLVRRDLGVTGEGIRVGVIDSGVDYHHPDLGGCFGQGCRVAFGHDFVGDDFVSGDASKPPAPDGDPDDCLGHGTHVAGIIGANGIVQGVAPDVTFGAYRVFGCRGGSRADIILKAMERAAEDGMHVVNISIGTPFQWPDYPTAAAATALVARGVVVVASIGNSGEKGLWAAGAPGVGEAVIGAASIDGTRVTRLSFTVAPGNAAIGYARAEGGPPPPLSGSAPLARTGTPASARDACDELPAGSLAGKIALVRRGGCPFHEKAARAQAAGAAGVVIYNDRGGVMNPSVASGGPISIPVVAIAQADGELLSARLDAGPLTHSWTDRAVAAQSSTAGLISGFSSHGLSAALSFKPDLAAPGGAIYSTIPVEQGSYDTLSGTSMAAPHVAGAVALLLDARPELSAPRVRDVLQNSAVPAPWSGDPSGQVPEGAHRQGAGVIRVDRAIRATTVISPGKLALGESEAGPAARKLTLENAAAHDVTYDLSHAPAACTTGGDHWRPTSATAGAAAVDFGAPSVTVPSRGRATVTVTIRASGALAEGGLFGGYLVFTPRGGAADGALRVPYAGFKGDYQSVPVLKLSGSGGAPWLGKLSGTRMVPQRSGATYTLASDDVPYVMVHFDHGAERVTLDVVEAATAKPWGRALSLSHVGQSSSATAVTRYGWKGTTKIDGRATVVPDGDYRIKLRALRALGDPGNEAHWDTWTSPVFTLDRP
>NC_021658.1|WP_020736375.1|6283835_6284543_+|RtcB-family-protein
MSARIAAWLPDGAGAALDASLARLARTEDVAHVAVMPDAHVADDVCVGTVTATTRRLLPAAVGGDIGCGMVALRLRADADLLADRDRAARLLSGLCRRVPHVLHPAAGTPPLPDDLAEARLGAPRLEAMKRREGRMELGTLGRGNHFLEVQRDEEGALWLLLHSGSRAMGPAIREHHEALAARDPSGVRFLEADSEAGRAYLADAAWAASYARASRARMAAEAAGLFAPLTDDRA
>NC_021658.1|WP_020736374.1|6283455_6283839_+|hypothetical-protein
MGKDRSRSREDARSVVDAGSLFGGTAAGKAQRKERQLCRQVQEAVSDALAALRDDVLQDVWVVQVEPAPDASRLAVVVQVGPGTPPDVAAARLARMAGYVRAEVAGAITRKRAPTLAFQVLPPEEEP
>NC_021658.1|WP_020736373.1|6282457_6283162_+|hypothetical-protein
MQNISTEQGESRQGEGQATTETSFEGQQRSAACPTLIESFLPVADIVVNEQIVVMATPEATYAALKRVDFARSPSLLLRAFLALRVAEARRARRRLRLAPLPAPARVSLQNVEDYGQIRLAEREGSEIVVGAIARPMNAESMYVRRSAAEFKAFDCPGHVKVAASYVVTPHGQRRTMLSYEVRIRATDTRTRRQLFFWDALTAPLMMAVTRRTLRYAAKFIERQCAAPAYRQAL
>NC_021658.1|WP_044986061.1|6280776_6282150_+|3-deoxy-7-phosphoheptulonate-synthase
MYVPAQPWSPDSWRERPNAAPMPYDDAASVDAAVDKLRALPPLVTSWEVERLKGHLAQAQVGRRFVLQGGDCAETLDDCSPNIVTNKLKILLQMSLVLVHGARRPVVRLGRFAGQYAKPRSSPIETRDGVSLPSYFGDLINRAPFEAAARRPDPGLMVAGYQHAALTLNFIRSLSEGGFADLHHPEYWDLSFLERADLPGELRERYQRMTEQVGEALRFMEALAEVPVGELSRVEFFTSHEGLNLHYESAQTRKVARRPGYYDLTTHLPWIGERTRQPDGAHVEFFSGVANPVGIKLGPKTVPGEVIRLLDRLNPADEPGKIVLIVRMGAGRVREGLPPLIEAVRSAGRKVLWMSDPMHGNTQTTAGGIKTRNFEDILTEIEASFEVHEALGSHLGGVHFELTGDDVTECIGAGLTESDLDRRYASLCDPRLNYRQSLEMAFRIAHRMAESSRRSKG
>NC_021658.1|WP_044986060.1|6279720_6280704_+|hypothetical-protein
MPPQASGTSASQGSPPDRPGSLPGTTTVLTAGGGAPAGRAALLSRAPAAARWLVAGAAAVVAVVLGAALLRDDGSLAQLEAAVSAERAGPAGSAPRRPVAPRPSDAVPADELAAAAAGGVLQLEALAARYPKDPSIFRALMLRHALPPPYHAAALAAAKRLLELDPGATADDDVKRVVSSAAGGPPEAASAALDLMATGMGSHGADLLYELSIGSSALKERAAKRLAEAAVLARATPALRVAHELRAAPSCKARQALLGRATADGDRRAIDALTPLVSSKSKGCGFLGMSRCAAPCASIAKEIKAAIQAIEARVGPSPGAADAPESR
>NC_021658.1|WP_049949580.1|6277979_6279653_+|serine/threonine-protein-kinase
MSDTERQAALAAVRAAQAQAAAAASPSTTAETVRPPPPPGGSEAAHDVAPVTVRPHNVPMGPAAAAHYATADTVRPPAPPASSAPGEPPVEADPLVGTTVAGAYRIVRLLGEGGMGRVYETHHTRIPGKRFALKTLHPELAQQPTILARFQREAEAAASVRNPHIVEIFDVNRLSDGRPCIIAEYLDGQGLGELLAASGGRLPVGAAVRIAREVCDGIAAAHAAGVVHRDIKPENIFLTGDPACPTVKVLDFGISKTSAPSGLTRTGMILGTPAYMAPEQAKGDEIDPRADIYAVGAVLYHALTGQRPFERSDPTAMLLAVMTEEPPAPRTVNPEIPPDLELIVQRAMAKEKEGRYASMGELASALAPFEEAPLPAQPPSASLGRPSVTLGRPYALSHAFGLPGSATSEAYLTRQMVFLSASLGLGWLGAGLVSCLAGLARAARSDSAALSGQGATLLTLGVLCALFGVGLLGGFYVFRHVWRDDTKLSALAPRLTTPVVLALVTYGVASLLVRLLEGVFLQRAVGIAWPVWDALLFLISVGAALAAALFQWRAERR
>NC_021658.1|WP_020736371.1|6276530_6277559_+|RNA-polymerase-sigma-factor
MTSPSPPSPPARPSFETVYAVGLPFLHRALRWLGVETNDVDDMLQEIFLAAHRALPGYEPWRYHGAPSPGLPTDGPPPLRITPEAALQRWLFGIAWRKTSHYHARAHRRREIPSGAGASWPFDGRDPTPSPEQSLASGDRAEIVTALLRKVAPERRVILVMYELLGVAVADIARELELKENTVRSRLRLAREDFRAAVARQSSERRGALRALTASERPLHAAAASLLRAAAVFPTVPAADAGALWLRLQHRIATCEGAADAPAVLTSPHRGERKTSPPRGERNQTERNKCEAGDRTASLTLPHVCVVSAPLAEKVLRSWPILRSGMSVCVTNGSPPRSRRSA
>NC_021658.1|WP_020736370.1|6276111_6276534_+|hypothetical-protein
MPNRTRPKALSRAPSTQNMARRARRRATLEVCGPGSHRPGGRLFHALCDLADRFLQRRGDPRATQLGTVLFYVAFHGARAAEDEDFRLSLRTSLDMLVELEPLERWQRPPPTPDPPGGRPAPRPYPTYAGADFPQMRGAG
>NC_021658.1|WP_129576083.1|6275619_6275937_+|PEGA-domain-containing-protein
MAGGNARRPRAALALLLLGLSSCVARTPATVSLRMKGNVPDASVTIDDQYIGALAYVAARGVALPPGAHRITVEKAGYFAWDRLVEAKSGDPPLHLQVQLTPVPD
>NC_021658.1|WP_020736377.1|6287533_6288166_+|class-I-SAM-dependent-methyltransferase
MTVLARALFSMHHRLVHVPRVGRVARALAAQVGRASSLLDVGAGDGTVALEVARRVGAQRVVGVDVKARPGAALPVVAYDGERLPFPDGAFEAVLLSDVLHHCARPAALLAEALRVAARVVALKDHFRFGPVSEKVLLLMDLVGNAAPGVEVRGTYFTPGELVELVRGAGGRITGLEWPLRIHDMPFRLVTQDRLQFAARVERPAGGGGR
>NC_021658.1|WP_020736378.1|6288162_6289125_+|NAD-dependent-epimerase/dehydratase-family-protein
MTGLRSFVVGGAGFIGSHLTDRLVERGPVTLYDNLSVGRRAFVASHLASGRATLVEADALDLERLTEAMAGHDLVVHLAANPEARWGLARTRLDLEQGTIATYNVLEAMRRTGASRLIFSSSGTVYGDTARRCAEGDLGALPISLYGASKLAGEALISAYVECFGLTAWIYRFGNVVGPRGTHGAALDFLKKLRDRRTELEVLGDGRQSKPYLDVRDCAEGILFGFDRAGERLNIFNLAPEDATSVSRIAELCVAASPYPDAVIRYQGGERGWPGDVPRSRMDPGKLAALGFRVRHTSDEAVRMAVEALASEVFGGEPAG
>NC_021658.1|WP_020736379.1|6289175_6289850_+|glutathione-S-transferase-family-protein
MAELTLYIGNRSYSSWSLRPWLALKHAGAEFDEVVIPLRAPGVRTPEIQRHSPSGKVPALKHGALTIWESLAIAEYVAESFPEAKLWPEARGARAVARAVSAEMASSFAALRTALPMNVRRKIQGVAITEAASQDIARVQALWNDCRSRFGQGGEFLFGRFSVADAMYAPVATRFDTYGVELDAVSQRYVASILALPAMQEWIAKAREEPHIIEAYEAIGVVGK
>NC_021658.1|WP_020736380.1|6289966_6291715_+|cation:proton-antiporter
MPHELDLILTLTGGLTAALAFGFITQRLRLSPIVGYLLAGILVGPFTPGFVADKGLADQLAEIGVILLMFGVGLQFHVRELLAVRKVAVPGALIQIAVATALGGLVGRAAGWSWAASIVFGIAISVASTVVLTRILSDSHVLHTPAGHLAIGWLVLEDVFTVLVLVLLPALLGGDAGAGATGIAVSVGLAVLKLAGLVAFVFIVGQRVIPTLLGYVARTGSRELFTLTVLVVALGVAVGSAKLFGSSMALGAFLGGLVVGQSDFSSRAASEALPMRDAFAVLFFVSVGMLLDPTQLAIGWPVAAATLAVVLIGKPLAALFVVVLLRRPLQTAFAVALSLAQIGEFSFILATLGRQLGIMPDEASQALVVASIASITLNPLLFSLRDRMARSTSALLLRRGAAAEAGAESAPVDESAHRTVVVGYGPVGRTLTRLLRENGIEPTVVELNLDTVRHLQGQGIRAIYGDATQREILERAGVGTADSLLFTSAGPSGDAVIEQAKGLHPGLFVLARAFYMREVAALKKAGADVVVTGEAEVAFSMTERLLVRLGATAEQVERERERVRSELFGTGAPAPHPAAPAG
>NC_021658.1|WP_020736381.1|6291737_6292676_-|DMT-family-transporter
MSHSERAHTLTGELPTGLLDDGRTFAVLSAATFALKAIFVKLAYAAHPIDAVSLLALRMGIALPFFLWLARRERGEAAERMTPRLWGGVLLVGFLGYYLSSLFDFIGLTYISTGLERLILFVYPTLVLLIGAVWLKQPVRAKAWGALAVCYLGLAAAVWHDLEQTGDARVVAIGGAWVFASAVTYALYYIGVGKLASRVGSTRLAAYCGATSCVMVLAHYAATGSPARLSELPAAVWWYAAAMATISTVLPIVLLAAAIRRLGAGRAATFSTLGPVLTIAFSWVILGEPFAWQQVVGLALVVGGVTSLGKSR
>NC_021658.1|WP_063752011.1|6292978_6293854_+|ABC-transporter-permease
MTSPAGPGTAARVPGALAAPGGPPPRRRRAPLAQEPSGVHQVGASFLQIAATVGGMAVLAGQIAARVATLRVDGAEFMRNLYRMGVKSMPIVVVTALFTGAIMVIQAAPLVERFGAHGLLGWGAGFGTLREIAPLLTALMINGRVGANNTAELGTMVVTEQIDALRVLAIDPVSFLIAPRFLAMVLTLLLSVIFADALALLGAAFTGDLLLGVAPAVFYNGLTSGLLGIGDVMSGLVKSVVFGVVLALSSCQYGLGVTGGAPGVGRAVNATVVASAAGIFILDYFVSFTLD
>NC_021658.1|WP_020736384.1|6293869_6294727_+|ABC-transporter-permease
MPPSHPSFPDRASAGPPSSELRDVAPELSGVAALGGAALSLLASARELYSVFVRTLYYCAKGRREPGAVLVQMYEIGNKSLFFLTVVMGFIGMIMVFQAGQQAKRVIPDLTMLGATYLELLVRDLAASIGALMLATRVGAGIAAEIGSMVVTEQVDALRMCAADPIDYLIKPRFIASLLMTTCLIVWSAAVAFTTGMVTAYSMFGVSPETFINVSLVDAGDLATGLAKCVAYGAAIPVVSGHSGLSTFGGSEGVGWATTRAVVNSSLAVIVLNMLISAAAFLIFR
>NC_021658.1|WP_044986062.1|6294752_6295493_-|ATP-binding-cassette-domain-containing-protein
MISFRNVRKSFGPKEVLKDVSFDVEDGEVFFIIGQSGVGKSVLIKHLVGLLYPDGGEIWLDGEEVSRFDEARMYPVRMKCAMVFQHSTLFDSMTCAENVALPLRKHKGLKPKEALAEARRRLEQVHMREFADRFPPELGDGMRKRVAIARALTLDPRYVLFDEPTTSLDPVSARRVDKLIRELSDTLGVTSIVVSHDLVSIFTIADRIVMLYQGLVRLLGDRAVFQGSEDPIVRQFITGSAEGPIE
>NC_021658.1|WP_020736386.1|6295654_6296677_+|MCE-family-protein
MASPRSIEVKVGILILTAIGLLATFILVMGGVNFQPKYSIYVEFDNPGGLQTGAPVKIAGVEVGKLSEIHFRGGQVGKDGRREPLVRIQLRVEERYQQSIHDNATFYVTTQGVLGEQFLAIEPGSTDRPVLPANAVVRGLDPPRLDMLLAEGYELLHATVTAMREHREEVGEAFDGLRKTLKGTGDFMHRNQDRLDRIAENVEQISLDGTDLVKDARQKYVNNPQIDRILANADQVSSTAARDLPPLMADARETLANARRLSTTVGGEPEQAKIKKTLDDIAEIAGRARAATADAQEVLAHVKRGKGTVGALVMDEQLFDDLQELARDLKHNPWKFFWRE
>NC_021658.1|WP_020736387.1|6296795_6297011_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit
MANVIKAHITGTVWKIEVKPGDKVEEGTVVVILESMKMEMPVEAEGEGTVEEILVTEGAAVTEGAPLIKLA

Crispr_ID: NC_021658_23

• CRISPR_ID: NC_021658_23
• CRISPR_location: 6544700-6544812
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_021658_23

Consensus_repeat	Method
GCCGCCTCAGGAAGCGCGGGCGC	CRISPRCasFinder

spacers of NC_021658_23

>23.1|6544723|22|NC_021658|CRISPRCasFinder
GGGCGATGCCGCCTCAGGAAGC
>23.2|6544768|22|NC_021658|CRISPRCasFinder
AGGAAGCGCGGGCGCAGGCGGC

CRISPR arrays and Neighbor proteins around NC_021658_23

CRISPR arrays

The CRISPR arrays of NC_021658_23

>merge|NC_021658|23|6544700-6544812|CRISPRCasFinder
GCGGCGTCAGGCAGCACGGCTTCGGGCGATGCCGCCTCAGGAAGCGCGGGCGCAGGCGGCGCGGCCTCAGGAAGCGCGGGCGCAGGCGGCGCAGCCCCAGGCGGCGCGGCCTC

>NC_021658|23|19|6544700-6544812|CRISPRCasFinder
GCGGCGTCAGGCAGCACGGCTTC	GGGCGATGCCGCCTCAGGAAGC
GCGGGCGCAGGCGGCGCGGCCTC	AGGAAGCGCGGGCGCAGGCGGC
GCAGCCCCAGGCGGCGCGGCCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020736573.1|6554118_6554607_+|SRPBCC-family-protein	unknown	unknown	gnl|CDD|367463
NC_021658.1|WP_044988610.1|6559293_6559860_+|2OG-Fe(II)-oxygenase	unknown	unknown	gnl|CDD|214780
NC_021658.1|WP_049949592.1|6556264_6559162_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|237057
NC_021658.1|WP_020736570.1|6552136_6552601_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_020736558.1|6532265_6534071_-|glycosyltransferase-family-39-protein	unknown	unknown	gnl|CDD|379080
NC_021658.1|WP_044986096.1|6547069_6551287_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|378942
NC_021658.1|WP_187346008.1|6541413_6542724_-|hypothetical-protein	unknown	unknown	gnl|CDD|215598
NC_021658.1|WP_020736563.1|6535697_6536333_+|hypothetical-protein	unknown	unknown	gnl|CDD|376165
NC_021658.1|WP_020736562.1|6535281_6535701_+|RusA-family-crossover-junction-endodeoxyribonuclease	unknown	unknown	gnl|CDD|377564
NC_021658.1|WP_049949591.1|6554739_6556056_-|hypothetical-protein	unknown	unknown	gnl|CDD|275359
NC_021658.1|WP_020736564.1|6536448_6538527_-|hypothetical-protein	unknown	unknown	gnl|CDD|215425
NC_021658.1|WP_020736567.1|6545696_6546584_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044986095.1|6542869_6544123_-|hypothetical-protein	unknown	unknown	gnl|CDD|223065
NC_021658.1|WP_148313811.1|6552688_6553975_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020736569.1|6551441_6552035_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_021658.1|WP_020736565.1|6538690_6540205_-|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl|CDD|277343
NC_021658.1|WP_044988611.1|6559935_6560796_-|NAD-dependent-protein-deacetylase	unknown	unknown	gnl|CDD|238700
NC_021658.1|WP_049949589.1|6530774_6532259_+|hypothetical-protein	unknown	unknown	gnl|CDD|237855
NC_021658.1|WP_020736559.1|6534067_6535057_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148313810.1|6540771_6541278_+|hypothetical-protein	unknown	unknown	gnl|CDD|198062

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020736573.1|6554118_6554607_+|SRPBCC-family-protein	gnl|CDD|367463	pfam03364, Polyketide_cyc, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. The family also includes proteins which are involved in the binding/transport of lipids.	7.04217e-11
NC_021658.1|WP_044988610.1|6559293_6559860_+|2OG-Fe(II)-oxygenase	gnl|CDD|214780	smart00702, P4Hc, Prolyl 4-hydroxylase alpha subunit homologues. Mammalian enzymes catalyse hydroxylation of collagen, for example. Prokaryotic enzymes might catalyse hydroxylation of antibiotic peptides. These are 2-oxoglutarate-dependent dioxygenases, requiring 2-oxoglutarate and dioxygen as cosubstrates and ferrous iron as a cofactor.	2.51917e-16
NC_021658.1|WP_049949592.1|6556264_6559162_-|helix-turn-helix-domain-containing-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	4.15098e-05
NC_021658.1|WP_020736558.1|6532265_6534071_-|glycosyltransferase-family-39-protein	gnl|CDD|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	4.57889e-06
NC_021658.1|WP_044986096.1|6547069_6551287_-|tetratricopeptide-repeat-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	1.476e-14
NC_021658.1|WP_187346008.1|6541413_6542724_-|hypothetical-protein	gnl|CDD|215598	PLN03138, PLN03138, Protein TOC75; Provisional.	0.000119613
NC_021658.1|WP_020736563.1|6535697_6536333_+|hypothetical-protein	gnl|CDD|376165	pfam18743, AHJR-like, REase_AHJR-like. REase Fold fused to HEPN(DUF86) pfam01934.	2.00156e-07
NC_021658.1|WP_020736562.1|6535281_6535701_+|RusA-family-crossover-junction-endodeoxyribonuclease	gnl|CDD|377564	pfam05866, RusA, Endodeoxyribonuclease RusA. This family consists of several bacterial and phage Holliday junction resolvase (RusA) like proteins. The RusA protein of Escherichia coli is an endonuclease that can resolve Holliday intermediates and correct the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.	4.06924e-09
NC_021658.1|WP_044988611.1|6559935_6560796_-|NAD-dependent-protein-deacetylase	gnl|CDD|238700	cd01409, SIRT4, SIRT4: Eukaryotic and prokaryotic group (class2) which includes human sirtuin SIRT4 and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span.	5.2053e-128
NC_021658.1|WP_020736564.1|6536448_6538527_-|hypothetical-protein	gnl|CDD|215425	PLN02791, PLN02791, Nudix hydrolase homolog.	6.69302e-18
NC_021658.1|WP_020736569.1|6551441_6552035_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	7.36898e-40
NC_021658.1|WP_044986095.1|6542869_6544123_-|hypothetical-protein	gnl|CDD|223065	PHA03378, PHA03378, EBNA-3B; Provisional.	3.61177e-07
NC_021658.1|WP_049949591.1|6554739_6556056_-|hypothetical-protein	gnl|CDD|275359	TIGR04566, hypothetical_protein_Q664_47920, outer membrane exchange protein TraA, N-terminal region. In Myxococcus xanthus, the protein pair TraA (MXAN_6895) and TraB (MXAN_6898) are required for contact-dependent exchange of outer membrane proteins. The C-terminal half of TrA consists largely of Cys-rich tandem repeats. This model describes the N-terminal region of TraA, and related protein MXAN_4924. This region is suggested to be similar to the lectin PA14. Members of this family are restricted to a subset of the Myxococcales, and so have a narrower species distribution than the MYXO-CTERM putative protein sorting signal (TIGR03901), which is universal in the Myxococcales. Note that TIGR04201 matches at least seven repeats in the C-terminal region of TraA. T [Protein fate, Protein and peptide secretion and trafficking].	1.48239e-86
NC_021658.1|WP_020736565.1|6538690_6540205_-|UDP-2,3-diacylglucosamine-diphosphatase	gnl|CDD|277343	cd07398, MPP_YbbF-LpxH, Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain. YbbF/LpxH is an Escherichia coli UDP-2,3-diacylglucosamine hydrolase thought to catalyze the fourth step of lipid A biosynthesis, in which a precursor UDP-2,3-diacylglucosamine is hydrolyzed to yield 2,3-diacylglucosamine 1-phosphate and UMP. YbbF belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	4.59046e-30
NC_021658.1|WP_049949589.1|6530774_6532259_+|hypothetical-protein	gnl|CDD|237855	PRK14900, valS, valyl-tRNA synthetase; Provisional.	2.71284e-11
NC_021658.1|WP_020736570.1|6552136_6552601_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	6.45918e-11
NC_021658.1|WP_148313810.1|6540771_6541278_+|hypothetical-protein	gnl|CDD|198062	smart00994, zf-C4_ClpX, ClpX C4-type zinc finger. The ClpX heat shock protein of Escherichia coli is a member of the universally conserved Hsp100 family of proteins, and possesses a putative zinc finger motif of the C4 type. This presumed zinc binding domain is found at the N-terminus of the ClpX protein. ClpX is an ATPase which functions both as a substrate specificity component of the ClpXP protease and as a molecular chaperone. The molecular function of this domain is now known.	3.59925e-05

Protein sequences

>NC_021658.1|WP_044986095.1|6542869_6544123_-|hypothetical-protein
MSRPHDGRARRARPARGASRPRRHVRRAALAGATALGAAYLLSIDAAHAEQAPRPRAARLEYVRGRGAERCPDASFLRAEVARVVGADPFRDDAPLLISATIERQGAELVASLALRDSDGKTRWADGFSTSRACEVLVAGMGLAVAAQLLSMPERGSREALPRGAAQAPHEAPGPMPPAQAPPGPPGPVPSAQGAQAPQGPSGHEQGPQGPPRASPPTQAARTAPAPSGRVAPAMPTSSGAGATAAPSEPLRIEAGLGATVGLGITPGVAAGTTLGIGARWSDWSVAVEARGLVSLATEVEGMPLGTTAFTVATVACLRGRHLFGCGLATLGAVRFVPEDPWNMRVRSKALFGMGARLGSAWRLSDRWSAHVHAEAIGIVEEARLRRQVDHAVTPAPLYWTSPPLGAAFGLGVTASY
>NC_021658.1|WP_187346008.1|6541413_6542724_-|hypothetical-protein
MRIYPLLMAGFLVLPGCAGDPTVYGPCQPSEYGSPACPYPEAGTGDAGDGGDGGGGSGGGGTGGGGTGGGEESACAGDCIPPAPLGWFGPALLWYGPPDQAPGCPAEAPNPGYKGFADLAPAPFACAACLCDPPASASCELPLGWSAHTAAAYQAPGCPAEAPNPGYKGFADLAPAPFACAACLCDPPASASCELPLGWSAHTAAACTAGGPGSVETAFAAPDGWDGACTAASAIPAGQDCGGQPCVQSLSVEAPAVLVTAACTPRVDEPPPPAREDPWQTRALACLPGAYTECPDDRSTCMPSPGEPGAPPPGGFLTCIFHEGDVTCESPYLDRHVFYGGAEDTRGCSACGCGAPEGASCTIMASVYSDGACAETLVSAVVSSTTPFCGVTPPGVALGSKSAEVVAVDPGACAPSGGEPTGELLPAEPSTFCCLA
>NC_021658.1|WP_148313810.1|6540771_6541278_+|hypothetical-protein
MTLDDEITEVEGLAQVARSAATESLERATNDLRLGREALDRYQRLVDAAITSAESTLRHCRKIAADPTDPARAPTTIVQGMLAATRESIGLMHAAVAIIDELAGAGGQLDAARGDRAHERGAAAPRSCSFCGDTGSKVVAGPEANICASCTRLACGVLGIELSASDTE
>NC_021658.1|WP_020736565.1|6538690_6540205_-|UDP-2,3-diacylglucosamine-diphosphatase
MDGAARDIFVISDLHLGDGGVRDNFETGKKTPQLRAFLDHVGSEGGELFVLGDLFELWQMNLSLLLVKRRPLLDQLASLRLTYVPGNHDIDLVHFIDTDFLHHPFFARMRAPFVRELGGKRFRFAHGHETDPFNAGDDPGFGRMLAIFAGVWEDENGSPLLESGGSVEDVLEQFGESMLTIWRRALATMHGRGAKRDVRPTSALTPAQNPDRLGEHVAGVRAALEKGGDHDVAVLGHTHKPGRIGGWYFNSGSWTGPHNPFLRISPDGHVRYLEWKDGREIEREMPVVRPEAGPGRAPAKKNPIAAAHAAARTLFPKPTRPERSRWVLIAQGALALAVGAGALTISVGQGSSAGWRLLVSAFAVYALADGALSLLGASREPPVRRLLSRVRGVASLLLGLLVLRRGYVVEIFVVLVGIWAFVSGALRVAASVVLKGMVESRWLFVVGTGSMLASLALLSLPASAVLLKYALSAYLCYYGAGELLAGIFGQRLPRTGWGPGPSRA
>NC_021658.1|WP_020736564.1|6536448_6538527_-|hypothetical-protein
MKTALPTPASRAPLAALAGLAALAAEAACVQPHAPPPAEPPKAAEPAPPAAQAAPSAPPFGQIPRLDLNRIAVELDLPLFWIGDRNGSGAVEPDEVAALWHHAKAPAWVAAGAFTPEFTSAYAAMLKIKAEGHPRAGLDEAEQRRRDAVLAELAAGRPSLLRSDFRGASAEDRAIVGHLLKVAALIDQIHAKQLGAAGMADKIPADDPASRALFWRNQGPWCEQPKTRNDPNCNALPGKPPRVSGAYPARLQQDKKFCAALEARRDQQALLSPFTVVVEEGGALKAVPYSEAYKPEMEAVSRELKAAAEAIQSPGEAAFKAYLLAASQAFLDNRWELADEPWSKMNAENSAWYLRVGPDETYWEPCSRKAGFHVSFARINQESLAWQKKLDPAKADMEGAFAKLAGAPYKERKVAFHLPDFIDVVLNAGDSRAATGGTAGQSLPNWGRVATEGRGRTVAMVNLDDDDSRAALREAAASLLCKATMESVSLEGPVATLGTVLHEAAHNLGPTQNYKVKGRTDNETFGGPLATMLEELKAQTGAVFFTGWLAQRGVLDPALARMAETLEVFWALRQVGQGMYTADGEPRPYGQLAAIQLGSLLDAGALGFYRGEAAANGADMGCFAIQADKLPAAAEALARTVLGIKARGDKAAAQRLRDDYVEKEGAWKALRGVIEERMQRVPLGSLVYAIEL
>NC_021658.1|WP_020736563.1|6535697_6536333_+|hypothetical-protein
MNAREAHDRAVQKLVDEYASKGFQVQKEAVLPFVLEGGRRLRADILAERDDEHHVVEVKLRGVRGELEARRWDEIARQIRARPGWHFKIVPIEQDPPPLPDPERIEAELTNVEALLDQDRLAAALLLAASAFEASARRRLLAAGALLRSDTPAALAEQLVAQGHIEQENFVPLRDAIELRNAVVHGHLDQLPERDAIQRLVADARRLLHAA
>NC_021658.1|WP_020736562.1|6535281_6535701_+|RusA-family-crossover-junction-endodeoxyribonuclease
MTRLELVVKGIPVSSQAEDRTNLKRWKERVAQAARDAIKEEDELYGECRGILVYFYFGSTDLDVDNIIKPVSDALNGIAYYDDKIVSEWIARKTDLGRTEIVDPPAVLAEHLARWMAAEQPFIYVCVVDEPPNHMELPK
>NC_021658.1|WP_020736559.1|6534067_6535057_-|hypothetical-protein
MTSAQRHETNSPAVSAARARGRLLHRWGLLVLLGLPALGLSELAAHLYSRQRTPDFDAWREVKAPLEAMRQPGDLVVVAPAWADPAARRALGDALMPLRDAARPDESRYAAAVEISVLGQRAEELAGFREEARQEHGRFVLRRLVNPSPARVVYDFVDHVGPASADARLTDPPAACRWNPRARIAAGGLGGHPTFPAARFECPGGPFFNVGVTVIADEEFRPRRCIWSHPPRDGEIVTRFRDVPLGAVIRGHAGMYWIIERERRGAPVTLSVRVNGETVGEATHHDGDGWAAFEFPLAAHAGAAKAEVEFAVRSPDYTHRHYCFEADTR
>NC_021658.1|WP_020736558.1|6532265_6534071_-|glycosyltransferase-family-39-protein
MKRTAPLAPADGLIAIAFAAAYVALLLATAGDLGYARDEGFYFFAANRYGAWFQALLEAPRAALRPEAVDAAWSVNHEHPGLIKSLFALSNLLLQKRLGLFAMEGTSYRFPAMALSGAGVALVYLWGTQARDRLAGASAAVLFAMLPRYFYHAHLACFDAPIVTVWAACAYAYWRSLRDGGALWPVLTGIAFGLALDTKHNSWFLPIVCVAHAAALELRERIVARPEAAEAAPAPPRGARRSVAALAAMATIGPLVFYALWPWIWRDTLARLREYASFHLNHEYYNMEFLGQNYWTPPMPRAYAPLMTAATVPAVTLFLFAAGLCAAARERLVYPLARAAARLAPESGRLAAAARALAARLRPPPPDAGGTALLWFLAIAAVYGAWLSPSTPIFGGTKHWMTAYPFIALFAGAAFSAAVRRARVGLRALLVARRSSGAFAPGAALAAAARGPLVPALLGAAVVAAPIAETLHAHPWALSAYTPLVGGAPGAASLGLNRAFWGYTTGAVVDYLNEHVPPRGTVYIHDTAGQAWDMLLRDGRLRKDIRGVGAVAGADFALYHHEKHMLGQAYQAWVAFGTTSPDHVGGLDGVPVILVYRNRAR
>NC_021658.1|WP_049949589.1|6530774_6532259_+|hypothetical-protein
MNERNLSRRLSTSIVDALKAHGHILVARGGATALARELEDKMAADIAAIAPRLEPWALVDGEVTTTFGTDEIDDQVEELVASLTSTLMDSEHVEDIFTEDNVIKRDVFRVMRDALLGPRPELGLEDDGPVHVRLDTLGYVASTVGKRAPAEVLRESLARAAQSAGGKLTSYDPELREATFSLGSSDPDARLEIEEAVADELSDLVEAKVVTLPMLERRFELQRTIDPGARAGLRQRIDAIASRMLREGGCAASWEIAGDRVLRLKLTPLSEQDALEVDSHMTEFTRDVAALLGEPLGAPGAASRPAAAPQRGEAPASRRREPAPQPVRADDDLEEAGVEEDDDLEDEDLDDEVLEDDDLDDEDLDVEGDAEDLEDEDLDDEGEEIEGDGEEVEDETPSKKLAARGKPRKPAEPASERPAASKPKAAARGAKKAPAKKAAAATKKAPASERAATGKTAATAAKKAAKAPAAKKSSPAPAKKAAKAPAKKAAAKKR
>NC_021658.1|WP_020736567.1|6545696_6546584_-|hypothetical-protein
MAKAKTQQHPTGKSPTATPTAHATYRACYQRFAPLAADLPDRDVEICRADVRIAFANVKRGVQAACADPARIRKALPELPLDDVLALPDLGRALIFAATRVTAKAASSREIDAKLKLVIELREPMLTLAETLAKRGLLPKDVVAEIRAGSGKYDLASDGMALAHLYAEHAGVLRGKHPFTQEELDQLREASEWLLDTLTPEGARRPAAKQRGEAEKMRDRLWTLLVRRYADLRKIAYYFHGDAFEDVTPKLLSRLSSSAGEDDGEEIEAEDGGSEDANGGGSGGAVEQPASPSSP
>NC_021658.1|WP_044986096.1|6547069_6551287_-|tetratricopeptide-repeat-protein
MSRSLSAMVDLRLDPGGALILSWTEAPGPRNKAVRPEEIAHLRRLTDAVSLAESQRESVAIVETRAALSAALVELLDGPERALGQRIARADAERRRLDLVVRARSDDRGALRVHPATWMRWELLPFAETRRRGAPPPLTVVLQLGSQDLGAPRVLEGGGLRIAFMAFSPHDVRPELDFEREEEELLAAIAPMAERRRARLRVVEGGTLEELRDVLLLERFDVVHLSGHGVRTPGGPRLVLEDAFGARRDVEPAELIEVLERAKAMPELVMVSCCNSADVRGSVASFAAELVAAGVPNVVGWTRPVGDGLAMLAASVLYEQIGAGKTPVEAMHLAREQMRREEERTPAPAHAWGTLHLVSGSAAGFRIDDRAEPLSERVDRDEVYRFLGSRMRVLKTGFVGRRRLVQRLLRVIVRGQDLEPKSGARDVAGACVFGMKGVGKSCVVGRAIERAKQHAPELGVVVVHGAIDERSVLDAFQEAVAVGGGDATAERLLARADERVFQRVRRLMAHWRRRPVVVVLDDFEQNLDRGTGGPWLVKPEAAALLEALIPTCATGKPKLLITSTAEFRVPWANERALAFVPVGALDDAAVRKLWARGRASNELANVSLEGWHDLADRLGRNARVLAWARALLAGKTDEELAAVAASASAKLPIWAPGDEASETKHAELAELFLRHMAYEQARAAFGEPALEFVRRARVFEDAVPKEAFAALAEGLAVDLDRDVDVLASWGLLEVGELDGARAYRVSPLVEPRFEADDAARWHEAAAEVWEALAAKGTSGVAWLERTEAAWEHALRGRHVARAERLARRIDAALYNAGLYAHNLRLAERHVEALPESAFGQRWLGSAEVMAGRSPSRAVERIRRSHSLLVRVHGTEEHPEVAASLHALGTVLRAQGDPAGARQALERSLAINTKVHGTEEHPEVAASLHELGGVLMEQGDLAGARRALERSHGLLAKVHGTEEHPDVAASLQALGGVLKAQGDLAGARVAFERSHSILAEVRRTEEHPSVAVSLHELGGVLMEQGDLAGARRALERSRGLVAKVHGMEEHPSVAASLHVLGSVLMAQGDLAGARRALERSRGLVAKVHGMEEHPSVAASLHVLGSVLMAQGDLAGARRALERSRGILAKVHGTEEHPEVAASLHQLGGLLRMQGDLAGARVALERSRAIKAKVHGTEEHPEVAASLHALGTVLMVQGDLAEARVALERSLAIKANVYGTEEHSAVAASLHVLGGVLMAQGDLAGARRALERSRGILAKVHGTEEHPEVAASLHQLGGLLRMQGDLAGARRELERSLAIKAKVHGTEEHPEVAASLQALAGVLEVEGELEQAAKLYRRALAIDKKCFGTLDQYHSAETEVALAMLLFRLGQREEAGGLLRHALQVLAEQVPNHPILQQFRARMPQPG
>NC_021658.1|WP_020736569.1|6551441_6552035_-|Uma2-family-endonuclease
MDEPDGKRLYSYAEYLEQERTSPTKHEFLNGEIFAMAGGTPEHARLCLSVGAELRAHLRGRPCVVYSSDLRVRVQATGLSTYPDVSVVCGRIERDPEDTDAALNPVVLVEVLSDSSEAYDRGQKFAHYRCIPSLREYVLVSQHEPRIEVFHRNEDGSWTLREARAGKGVELQAIGCILSVDDVYRDPLAQAAPAAEG
>NC_021658.1|WP_020736570.1|6552136_6552601_-|hypothetical-protein
MGYRSAFVLVFMAAGMLALGGCNRGYQTAAELESAERGPTHCASSCHSLGMRMSAFVLVDRAVAGCVCEPVQAPAGAYAAPRPAAPPPAAVPPPAAPPPAAVPPPAAVPPPAAAAPAAQPQSRASVAAAAGYAVIEAHRKHEEEQQALRSAQPK
>NC_021658.1|WP_148313811.1|6552688_6553975_+|hypothetical-protein
MGRPARGHAAVLPSRRVWHARYREGRPVDCQKRHRRGPPLALVRGPAGQRALPGEAMKMHDGYLALLASGGKRKLRANSLLAYGDEESRFEAAVLFHEAADIERRALALLEDVEPETRLRAAVERCACLVMGLDVVEAARAFREVEEASAAVPQETANAHRDRLDPLYFAARQDLTELLKRAPVLVSSRFRWEQIAETDRSRARAELDALLQRFPGESTFHLVDARAALDERRFDDLGRAVRRAHRLCPDNPLLRAYMLLVIAQSIAYPGSATTREEAEAELDRTYQELSREPADGVVYLGFMTASLAAFLAAFYAGEDAAEVHGKRARWAAEIAAQRRSIVSADIGKYIEAAGPFIGLLTTQPQMLTAVIENTLREALLNSDIGRASGESLQQPKAASLIRGVISQASRWLTPSAELAELSELALAA
>NC_021658.1|WP_020736573.1|6554118_6554607_+|SRPBCC-family-protein
MPTIQSTAEIDAAPDELFALSQDYDLRLEWDPFLREMRYRDGATAPAVGVRVWVRAKNGLSMEARYITLNPPEQVAITMVDGPRIFRQFSGAWLFKALSPRRTRVTFRYNFAARPRVLAPVLEPVLAAVLRRDIEQRLAGLKQSAETTDILQRLPRRGPAAT
>NC_021658.1|WP_049949591.1|6554739_6556056_-|hypothetical-protein
MSPRPSSLTVSSVIALSLALGASGSASAEPVIITGDPVAPLPAEKGAGLCGAHRISTDPEVDFYVSPATAEGFIEKMTAFFDPGQPETDIESFVVSAPLDFSNNYAVGNEWSFGDFLNAAPECSEGGCDFESNEPNVAFGMRLRGYLAVSPEHVEQPVHFGIFADDAVALVLYDVEQTAYPVLAQPLKLGLTTWRMTNTVTFAKEGLYPVEVLYAGIAEHSALEVSLLVGEFEDFQLGAGESGSVSLEESGFAIIEPASLYQALSGVDASPDEASCTQCGREFIHQVGNNGCAEGSYCNSAALCAPCSLDEFCGPTCRRCDAQTPRCAVVEGTPECVACVSDGDCGDGEVCDLEAHACVEAPDEPGAGGAGGAGGDGAGAAPGPGSDGDDGGCGVSGERRSGGGLAFALAGLGLALAGARRRARAASRSSALTERLSR
>NC_021658.1|WP_049949592.1|6556264_6559162_-|helix-turn-helix-domain-containing-protein
MAQVPRAGRGAEPAVHFNHALLLRARLDLDLTQEQVAASIGVDVRTYRRYESGAVNDPRLGFSVRSPSRRRILERLGAELGLAEADLLVGEAGGAPAAEGTAASGAGEAAAGAGEAAARAEEAPARAEEAPAGAAAAAEAQAPPIAPAAAQGAAPAWRPLHAHTLQRARHFVGRGEILDRLAAWAAASPPSPPVIALLGVGGAGKTSIAERFLQGLGDAPRPGGVLVWSFYDDPRTEAFLDQASAYFAPGPGASGAAAPRAPAAPGEQLARLKEALGQGPPHLLVLDGLETVQAEGGAGRAHGELHDALLRRLLCAIAAGLGGARALVTSRFELADLAAWADGGLATIRPEPLGEGDAASLLRRWGIRGDGDVLRALFEQTGGHALSVAVVGSYVGAFLGGDAARLSAAGAAHLAEAERDDVLARRLSSVLSAYARALPPGERDLLARLSVFPGGAGEAALLQLIRAGGEIAGAMAGWGPAELARGLARLERLGLVFAARQGELGYSTHPFVRQHFKSLLAVPPDRIHAAGSAAPPPRLDEAPRRAPRERRAVDAYEAILAELLGAGRAGEAYEIYAFGLGGFAHLGLKLGDMARGARILRAFAGGDDPRGMPASLPARVRASLAYDAGLYAGALGDLAFACACYAAHNEIAGALADPAPLSTGLRTLAYTERLRGRLTEARRLLERASEVDRRGATSGVRASDSGQAVRIAALLAAVLHDLGEVDAAGEHFARVRELGDAPVARRALWEAEHDLALGRRDRARGATERNIAECRRRGWEGHVAHGHTLLGLALLDGGGGGDEGGGGRVAQAEAHLVEARRWASATGEVEVALRCHELAARLALAAGRPDEGARQALEGLHVAETCGFGPFRARLAVVAARCALARGAGEAASAAALADAAVAWAGEDAWARADALHWAGVARAAAARGGELARGRDLLAEATALRERLRHPEAGASRAALAELG
>NC_021658.1|WP_044988610.1|6559293_6559860_+|2OG-Fe(II)-oxygenase
MHAERPAQRTTYTDDLRIFTVTDLLSPEECDGFIARAEAHGFAQAPIGGGSVINLEVRNNGRVMLDDPALAARLWERLAPWTPPTWGALRAVGLNERFRYYRYAEGEYFNWHGDGSFPRSEIERSLFTAMIYLNDDFEGGTTDFWGGQSIVPRRGMALVFEHRRLHRGAAVTRGRKYVLRTDVMYRRG
>NC_021658.1|WP_044988611.1|6559935_6560796_-|NAD-dependent-protein-deacetylase
MPLSHALLADPVDDLIALLRGKRFVALTGAGCSTESGIPDYRGPETRRRARNPIQGREFSSSAEIRQRYWARAVIGWERFSRAEPNPAHRALARLEQGGLIEGLITQNVDGLHQAAGSRRVIELHGTLAEVACLACGAMEPRAALQQRLLARNPGWLRLAADVAPDGDADLPAEHVAGFQTPPCLRCDGPLKPRVVFFGENVARPVVDAAFALVDAAEALLVVGSSLAVFSGYRFVLRAAQRGIPIAMVNLGSARGEELGALKVEARAGEVLPRLADALAGAPRPE

Crispr_ID: NC_021658_24

• CRISPR_ID: NC_021658_24
• CRISPR_location: 6751541-6751757
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_021658_24

Consensus_repeat	Method
CGGGTCGCCCCAACCTGGGTCGG	CRISPRCasFinder

spacers of NC_021658_24

>24.1|6751564|41|NC_021658|CRISPRCasFinder
CGGCTGCTCCCCCCACCCCGGCCTCAACCTGGGTCCACCCC
>24.2|6751628|40|NC_021658|CRISPRCasFinder
CGGCTCAGGCAGGCCGGCGAGCGCTGCCGGCACGCCTCGG
>24.3|6751691|44|NC_021658|CRISPRCasFinder
CTCGCCCCAACCTGGGTCGGGTCGGCTCCAGCCCTGGGTCGGGT

CRISPR arrays and Neighbor proteins around NC_021658_24

CRISPR arrays

The CRISPR arrays of NC_021658_24

>merge|NC_021658|24|6751541-6751757|CRISPRCasFinder
GCTCGCGCCCCAACCTGGGTCGCCGGCTGCTCCCCCCACCCCGGCCTCAACCTGGGTCCACCCCCGCCCGGCCTCAACCTGGGTCGGCGGCTCAGGCAGGCCGGCGAGCGCTGCCGGCACGCCTCGGCGGGTCGCCCCAACCTGGGTCGGCTCGCCCCAACCTGGGTCGGGTCGGCTCCAGCCCTGGGTCGGGTCGGCTCGCCCCAACCTGGGTCGG

>NC_021658|24|20|6751541-6751757|CRISPRCasFinder
GCTCGCGCCCCAACCTGGGTCGC	CGGCTGCTCCCCCCACCCCGGCCTCAACCTGGGTCCACCCC
CGCCCGGCCTCAACCTGGGTCGG	CGGCTCAGGCAGGCCGGCGAGCGCTGCCGGCACGCCTCGG
CGGGTCGCCCCAACCTGGGTCGG	CTCGCCCCAACCTGGGTCGGGTCGGCTCCAGCCCTGGGTCGGGT
CGGCTCGCCCCAACCTGGGTCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020736735.1|6765059_6765767_+|DUF4336-domain-containing-protein	unknown	unknown	gnl|CDD|372974
NC_021658.1|WP_148314864.1|6743880_6744819_-|AEC-family-transporter	unknown	unknown	gnl|CDD|223751
NC_021658.1|WP_080682255.1|6740562_6741102_-|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|225039
NC_021658.1|WP_044986120.1|6770175_6770523_+|hypothetical-protein	unknown	unknown	gnl|CDD|235082
NC_021658.1|WP_020736731.1|6754501_6760519_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_021658.1|WP_020736723.1|6741753_6743304_+|Hsp70-family-protein	unknown	unknown	gnl|CDD|212667
NC_021658.1|WP_020736722.1|6741157_6741643_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949597.1|6763316_6764951_+|amidase	unknown	unknown	gnl|CDD|223232
NC_021658.1|WP_080682256.1|6765914_6768629_-|RICIN-domain-containing-protein	unknown	unknown	gnl|CDD|379501
NC_021658.1|WP_020736732.1|6760540_6761674_-|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|224871
NC_021658.1|WP_148313832.1|6751835_6752801_+|PD40-domain-containing-protein	unknown	unknown	gnl|CDD|369459
NC_021658.1|WP_020736720.1|6739625_6740561_-|RNA-polymerase-sigma-factor-SigJ	unknown	unknown	gnl|CDD|132002
NC_021658.1|WP_020736728.1|6749753_6751244_-|hypothetical-protein	unknown	unknown	gnl|CDD|271320
NC_021658.1|WP_044986119.1|6762103_6763222_+|hypothetical-protein	unknown	unknown	gnl|CDD|377643
NC_021658.1|WP_020736719.1|6738782_6739616_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
NC_021658.1|WP_020736730.1|6753453_6754440_+|response-regulator	unknown	unknown	gnl|CDD|381147
NC_021658.1|WP_020736727.1|6748043_6749525_-|hypothetical-protein	unknown	unknown	gnl|CDD|271325
NC_021658.1|WP_044986117.1|6737703_6738576_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224995
NC_021658.1|WP_020736736.1|6769618_6769951_-|YnfA-family-protein	unknown	unknown	gnl|CDD|235016
NC_021658.1|WP_020736726.1|6745197_6747186_-|transketolase	unknown	unknown	gnl|CDD|223100

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020736735.1|6765059_6765767_+|DUF4336-domain-containing-protein	gnl|CDD|372974	pfam14234, DUF4336, Domain of unknown function (DUF4336).	6.25099e-15
NC_021658.1|WP_148314864.1|6743880_6744819_-|AEC-family-transporter	gnl|CDD|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	3.28509e-40
NC_021658.1|WP_080682255.1|6740562_6741102_-|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	1.14668e-24
NC_021658.1|WP_044986120.1|6770175_6770523_+|hypothetical-protein	gnl|CDD|235082	PRK02888, PRK02888, nitrous-oxide reductase; Validated.	0.00765341
NC_021658.1|WP_020736731.1|6754501_6760519_+|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	5.65453e-91
NC_021658.1|WP_020736723.1|6741753_6743304_+|Hsp70-family-protein	gnl|CDD|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	3.08871e-77
NC_021658.1|WP_049949597.1|6763316_6764951_+|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	9.65808e-100
NC_021658.1|WP_080682256.1|6765914_6768629_-|RICIN-domain-containing-protein	gnl|CDD|379501	pfam14200, RicinB_lectin_2, Ricin-type beta-trefoil lectin domain-like.	2.92788e-27
NC_021658.1|WP_020736732.1|6760540_6761674_-|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	5.05562e-25
NC_021658.1|WP_148313832.1|6751835_6752801_+|PD40-domain-containing-protein	gnl|CDD|369459	pfam07676, PD40, WD40-like Beta Propeller Repeat. This family appears to be related to the pfam00400 repeat This This repeat corresponds to the RIVW repeat identified in cell surface proteins [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	2.53481e-05
NC_021658.1|WP_020736720.1|6739625_6740561_-|RNA-polymerase-sigma-factor-SigJ	gnl|CDD|132002	TIGR02957, putative_sigma_factor, RNA polymerase sigma-70 factor, TIGR02957 family. This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.	3.91684e-94
NC_021658.1|WP_020736728.1|6749753_6751244_-|hypothetical-protein	gnl|CDD|271320	cd05819, NHL, NHL repeat unit of beta-propeller proteins. The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.	7.91168e-05
NC_021658.1|WP_044986119.1|6762103_6763222_+|hypothetical-protein	gnl|CDD|377643	pfam06283, ThuA, Trehalose utilisation. This family consists of several bacterial ThuA like proteins. ThuA appears to be involved in utilisation of trehalose. The thuA and thuB genes form part of the trehalose/sucrose transport operon thuEFGKAB, which is located on the pSymB megaplasmid. The thuA and thuB genes are induced in vitro by trehalose but not by sucrose and the extent of its induction depends on the concentration of trehalose available in the medium.	0.00266203
NC_021658.1|WP_020736719.1|6738782_6739616_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.3531e-27
NC_021658.1|WP_044986117.1|6737703_6738576_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	3.01444e-35
NC_021658.1|WP_020736727.1|6748043_6749525_-|hypothetical-protein	gnl|CDD|271325	cd14955, NHL_like_4, Uncharacterized NHL-repeat domain in bacterial and archaeal proteins. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	0.000757508
NC_021658.1|WP_020736730.1|6753453_6754440_+|response-regulator	gnl|CDD|381147	cd19920, REC_PA4781-like, phosphoacceptor receiver (REC) domain of cyclic di-GMP phosphodiesterase PA4781 and similar domains. Pseudomonas aeruginosa cyclic di-GMP phosphodiesterase PA4781 contains an N-terminal REC domain and a C-terminal catalytic HD-GYP domain, characteristics of RpfG family response regulators. PA4781 is involved in cyclic di-3',5'-GMP (c-di-GMP) hydrolysis/degradation in a two-step reaction via the linear intermediate pGpG to produce GMP. Its unphosphorylated REC domain prevents accessibility of c-di-GMP to the active site. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.12936e-48
NC_021658.1|WP_020736736.1|6769618_6769951_-|YnfA-family-protein	gnl|CDD|235016	PRK02237, PRK02237, YnfA family protein.	5.78503e-38
NC_021658.1|WP_020736726.1|6745197_6747186_-|transketolase	gnl|CDD|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0

Protein sequences

>NC_021658.1|WP_020736728.1|6749753_6751244_-|hypothetical-protein
MMLAAGCTIQVGGGQGGAGGEPATGSGGAAVCVPGSQLSCYSGLPGTEGVGLCTAGAQTCLPDGSGYGPCTGEVTSSAEDCATDADEDCDGTGQCSPPLWSVALGGDGPASASAVAADAAGNLYVTGWFEGTVDFGAGPLVSARRNDVFLLKLDPSGHAIWSRRFGTMNPGEAGTSIALDASGNIFLGGSYGVDIGLAPPQPPIDFGGGPLPWDDASWLAAFLVKLDPDGNHLFSRGHLFGDELSITVQDLAVGEAGTSAVMVVHSGFFDIGYDVMTYDAAGGYMWGFSRRTFSSEAPTGRVAMDSAGNVLVAMGRGDGQESCPCDYYFHVEKRDPEGTVLWLKLLSGPSEPDFSGDGGQAKDVAVDPDDNVLVAGRSLGNFDLGGGPIPAGTNFVVKMSPLGDYLWHREVPGDAVVADSAGNVIVLGGGALVKLDASGAALWRRTFTDTIWASRKLTTYHDGHLALVGSFEGTVDFGAGPLTAAGRDGFVTVFPP
>NC_021658.1|WP_020736727.1|6748043_6749525_-|hypothetical-protein
MMLAIGCTIQVGGGGGGGGEPATGGGGGGTAVCVPGSQLSCYSGGPGTQGVGLCTAGVQTCLPDGSGYGSCTGEVTPSAEDCATNADEDCDGIGQCSPAPLWSAGLGGAGSDAAYAVATDAAGNLYVTGWFEGTVDFGAGPLVSAGANDVFLLKLDPAGHAIWSRRFGSSDYGESGTKIALDASGNILLGGSYGGALLDGPPPVDFGDGPLPWNYDFSTSAVFLVKLDPDGNHLWSRGHIVPTGALSINLRDIAVDAAGNSAALLAYPSSVDDGMSFLTFNAAGEYMWGFTHRTFVSSPGGVAMDSAGNVLVAMADSSGVGICPCDYAFHVEKRAPAGTVLWRKRVSGPDAWDDGGEAKDIAVDPEDNLLIVGRSLGNLDLGGGPIPAGTHFVVKMSPLGDYIWHREAPSDAVFADSAGNVIVLGEGSLVKLDASGAELWRRTFTGTPATIRGLTTYYDDGLVLVGDFTGTVDFGAGPLTAAGSDGFVTVLAP
>NC_021658.1|WP_020736726.1|6745197_6747186_-|transketolase
MPDFAKLAAACTMARGLAMDAVHACSSGHLGLPLGAAEIGAALYGDLLRHDPSEPHWLNRDRFVLSAGHGSMFLYGWLHLSGYPVSIDDIRRFRQWESKTPGHPEYHYTEGVEATTGPLGQGVGNAVGHAVAAKMLAARYNTQEHTIFDHTVWCLAGDGCLQEGVAAEAAAFAGHFKLDNLILIYDANDVTLDAMAVKTQSEDTAKRFEAYGFEVLHIEQGNDLQAVHRVLGQARASKSGKPKFVVAHTLIGKGIPEVAGTQKAHGEGGAKFVDQARKNLGLPPEHFYVSEEVKQFFAKRKEELGKARAAWESTFQAWRAKNPELAQKLDEGTSRKVPADLDARVPAFAAGTKVATRKAGETVLQAVAEAVPALIGSSADLYGSTFNYIASSTDFDPEHPGGRNIRAGIREHGMGAIMNGIAYHGGLRPSGATFLVFADYLRPSIRLAALSHLPVIYIFTHDSVGVGEDGPTHQPVETVAGLRAIVDLDVIRPADAEETAGAWIAALERTDGPTVLALTRQAVPMLPGDAAAKREGVRRGAYVLVKETAALETILIATGSEVQHAVEAAKRIGPGVRVVSMPCVERFARQDRGYREAVLPAACTRRVSIEAGVTFGWHQWVGSKGLALGIDRYGTSAPGDIVMDRLGMNPQAVVQAVQDLVP
>NC_021658.1|WP_148314864.1|6743880_6744819_-|AEC-family-transporter
MPSGDLISQLLALFAVLGVGVLLRALGRGGQADAAALNRLVIDVTTPALIVSVLRRSGIGQGAWGAVAASTIALFACALAGVAVARALGLPRAAQGAAGLVGSFSNTGFLGVPVVLALYGRAGDAAGTAILVDSIVTMLMLWTFGVALAARMGAGGDVDARSLLRVILHPNVLSIAAGLALYALPIPLPTWVERALDALGSATPTLVFLALGLSLDLRSLRGRVRPLVAVAAVKLLVSPAVALGAAVALGLRRPVSEVAVLQSAMPTSMVSVIVAARYGCDGQFAAAAAVVTTLGALVTLPAVIEALRRLLA
>NC_021658.1|WP_020736723.1|6741753_6743304_+|Hsp70-family-protein
MRLGIDFGTTRTVVACCDRGNYPVISFQDTAGDPVDFYPSVAAERRGELRFGFDALAVASDPEWTVLRSFKRVLSGPRASPDFEVEIGGTKLRVLDLLTLFLSSLRDAVLHRSNRPKKKDDDGRLICVVATPANAHGTQRFVTLDAFRRAGFDVIALLNEPSAAGFEYTHRYRSTITSKREHIVVYDLGGGTFDASLVHMTGRSHDAVATAGLNHLGGDDFDAALGEMALAAAKIEREALPARALAALADQCREAKERLNPNSRRIVIDLEACLGDLAPAHEVTISASDFYDRCVPLVEATITAMQPVIARLDAGAGEALADIAGIYVVGGASSLPVVARTLRERFGRRVHRSPYPSAAIAMGLAIAVDEDAGFELSDRLSRHFGVFRESSGGEEVVFDPIFDREARVPSSHEAPVVSRRVYRAAHNVGRYRFVECAALDRLGVPHGDITAFNEVVFPFDRRLRERAAELAAVPVQRMTSEGPLIEEQYAITSHGIVEVTITDVEAGYQRVYQVGA
>NC_021658.1|WP_020736722.1|6741157_6741643_-|hypothetical-protein
MDPSDPNLPTPPDRGKQSQLLGGVISTSIGVVLLAVGLVQLLFFDLPGKTPRLTIELILIPMGLVFGIPGALELRRSLLNRWVMRHGVPAQAEVLRRDFTKKEYDGNPVSRLRLRVLPRDGAPYEVTIDWIAHTELMMLTPGRVVPVKVHPTKPRAVVIAA
>NC_021658.1|WP_080682255.1|6740562_6741102_-|carboxymuconolactone-decarboxylase-family-protein
MKKNAERAPDRRGVTGGEAGSSSGGGARGPRTRRATVSDRTAVKYEQEIPDVLQALAGVHKAMDRHGFDRKLIHLVQLRASQINQCAFCVKMHTRDARQDGETNERLDRVIVWEHVSDFSERERAALAWTEALTVLDRRTDYAALRTRLREHFSEQEIGVLTSAVAMINLWNRIQVSRH
>NC_021658.1|WP_020736720.1|6739625_6740561_-|RNA-polymerase-sigma-factor-SigJ
MTQEDDVAAFEATRPMLLGLAYRILGSRAEAEDAVQDTFLKWQSADRSAIENPASWLTTLCTRRCIDLLRAARNARVDYVGAWLPEPIHASTEGEPGERLSLAASLQTAFLLVLERLTPKERAAYLLHEVFDVSYPEIAATLGLQETTCRKLVSRARANVAQSKVRHATPLDRQERLLAAFQTAVASGGTEQLSALLSDEVELCADGGGKVPTLREVLRGRAEVLEFVGRALHAYWGDYTWEATDINGGRGVVLWKDGSAVACVSFAYDEQGAATNVYIVRNPDKLARLGEGVARGDGGGGVAPGGAGEAG
>NC_021658.1|WP_020736719.1|6738782_6739616_+|helix-turn-helix-transcriptional-regulator
MRATGTQDHAASAPRPRLGPRVDVLETPGGVVALEPSSNHRLRMLTGPPVRGSCGVHRFLYTRGDTDVLPAGFADVWHEDDPNTSLLLELPASLVRRAAMDMGRDPDTAGLDLRHQLRDPQIEHIAWALDAERMAGHPNGLLYAESLGLALAVHLLGRCAAPSRSQRGLSPQQLRRVTAYIEEHLDKNLSLERLADVAELSASHLKTLFKRSTGLPVHEYVVQRRVERAKALLARGDLPASQVAIEAGFAHQSHMARCMRRVLGVTPTALARRSPRR
>NC_021658.1|WP_044986117.1|6737703_6738576_-|NAD(P)-dependent-oxidoreductase
MSEVSVIGLGRMGIALAGALLRSGARVTVWNRTSAKAEPLVAEGAALASSVAAAVQASSVVVVCVADYQATYGLLEATQVAAALAGKVLVQLSTGTPMDARDGEAWAKARGADYLDGAILAIPSQMGKPESSIIVSGSATAFQKSKALLERMAGNVSYLGGQVGSASALDLAFISFVFGGLIGFYHGARICESEGLRVGDFGSMIADVAPAVGGMIKQDGEAIQVGTYESPESSLEMCARGAEIVLRQAREGRIDAVIPAFTEGLFRKGVAAGYGAESPGALIKVLRVAT
>NC_021658.1|WP_148313832.1|6751835_6752801_+|PD40-domain-containing-protein
MSEQKSARPTPSAGLPECTSSARRSRWLGASWRLSWRLALALGGVACEDQQVVIGVFTPERPRFTAPQKVATLNDDIARDEDPTLTGDLLEIHFMSERGTSQDIWISRRAGLDSPWETPTVDLAENLNTEDDDDTPAISNDGLRMWFFRGSAERSGIWMSERASRDAPWGEPSYVDALNPGHDDGTQAMNPHVDLPELRAVVGLNGPATQSWDLAIASRERPEDEWGEFVPLAELNDAGDQLAPFLFDDGRQILFRSGDDLYWARRPGTNDAFEPPQPLKEVNVPDARENDPYLSPDGSILFFSSERSGGTDIYEARRIAP
>NC_021658.1|WP_020736730.1|6753453_6754440_+|response-regulator
MQAQESRPTGLVLIVDDSADNLNVLSDALISDGLEVAVACDGEEAIELAGLTQPDLILLDALMPGLSGFETCQRIKADPATRSIPVVFMTALAEAKFRIEGFRVGAVDYVTKPFEKTELLARVHTQISLRRATRAIEEQNRRLSEEIRERARAEEALADAVQTLRDTNARLSDQLLQGERAEAARAALQDQIIAAQRERLLELSAPLIPIIDGILVMPLVGTVDVERARQAVETALHGASERGADHLIIDITGVRSVDETVAHMLVQAATGLSLLGTRTVVTGIRAEAAQTLVRLDLHLDHVVTKATLQSGVEHALRTRGRRRREREL
>NC_021658.1|WP_020736731.1|6754501_6760519_+|AAA-family-ATPase
MDLRDYAVGEVLHEGTETRVCRAVHRPSGDRVVLKLPAAPEPSSRVTGRLLHEHHILTQLEAVPGVPRARELLQQGGAVGLALEDPGLRSLDRVLAERGRLPVDAGLRLGALLARVLEAVHAAGVTHKDVKPQNVLVDAAYSQVKLLDFGIASSLPLEATAASIPEGLEGTLAYMSPEQTGRTARAIDARTDLYSLGVTLFEALSGRLPFTDRDPLSLVHAHLAREPPALDEVAPEVPPGVAAIAVRLLAKNPDRRYQTARGAAEDLERALHLWRERGAVERFPLGSRDFSHKLRLPDVLVGRERERELLGACFARAAEGAAELVLIGGPSGIGKTALVRTVYGDIAARGRGLLISGKHDQLARSTPYAAMAQAFGALMQQWLASPKPVLSAWRERIEAEVGENARLIADVVPELDRIMGELAPVPPVQGDQVLARQRLTWLDFVRAVTAPNAPLVMFLDDMQWADSATLEILKTLLTDAERRDLLVIAAYRDNEAPPEHPLWRLVASVEESGARVSRMSVRPLSEAHVQAWAARALDSEATRVEPLSRVLWHKTRGNPFFMEQLLLSLHKQGKVVRDPESGAWRWDQRDLEQAQITDNVVAFLTDKVLEMPEATQQLLGLAACAGHTFHLHDLERLSGWERARVTGALWPALQEELLVPADGAYRTAQALGQSGEGAPDAEYRFLHDRVQQASYERASPEQRVLAHLEIGRRLWARYRAQGGTPQQLLELARHLNLGSARMDAEDERASLARLNLEAARAAKAASSHRLLASLAEAGLALLGDGAWREHPALSAELALERLEAAFLMREFDDVEARSARLLAMPLPALARLSVQELRVRCIQAAGQFARGVELGLAALAEQDIVFPDADEARRAALLEESAELDRWFEGDPEAFDRMPPDPSPAHVLVDALTMHLMVCAAIGGQPILSALVIVRAVLRVRRQGVLTPVSPFIIVCFANVWSLTTGLYRRAASWVGPGVRAAERVASPFLAECLSFEGQYTAYVRPADEMAPIFERTCATGLKVGSFQGASWGLEGDLFYYRVWRGQPLGQIEAHRAARWGLMQRAGTALGTHYFEAVASWCGLLSTADGAGRLRSEEPFSRGSRSLLADGDVMAAELARILEAHLFLAAGAPPMALARAREAEQFRMSIFGFPPVTDVPLWLALAAARCWPEVTDAEERARLREHIEEGLARLRYFAEGSEDNFLHKLRLLEAEHARVQGKTDEAMARYDEAIELARGQRFLHIEALAAQLSAEFHLEAGRRRIGALYLREARDAYLRWGAHALVAHLEARWPALLRAPAQPSAAERRLATGVSTLTTTGVAGGAQLDVNTAVRAARALSSELDPERVVGRLMELVLESAGAQRAALLLAEGEELSVVARLSVHGGRIETGLSEPLSQSAEVARTVVNYVARTSEPVVADDARADARFAADPYLAAHPVLSLLSLPLSHRGRLLGVLYLEHREVPAAFPERRVELLSMLAAQAAIAVENALLYRDLEAKIKERTAELRVAKEAAERASQAKSDFLSSMSHELRTPLNGIIGYAQILERTPELPPAWRDGLSVIQKSSQHLLSLINDLLQLAKIEAGKMDAVVTVVRLPALVQMVVDLCRVRAEAKGIAFTHELRGPALEAVRADEKRLTQVLLNLLGNAIKFTERGGVLFRVDVLDERAPAGRMVRFRVEDTGPGIAAEHLSRIFEPFEQVGEQGARSEGTGLGLAITKKLVEQLGGAIEVQSEVGEGSAFIVTLPLAEPRPAEQAASPGEARRWDAIVGYRGERRTILIVDDNPQNRAVVRGLLGPLGFELCEADGGEAALRVAAERAPALILMDVYMRGMDGCEATRRLRRMPELRGVAILASSASVSEAEQQKCAAAGCDDFLPKPIQASALLDKISRLLGVEWLRRDEAPAQGSPAERAADGDGDGGHLTPPSADDLATLSALASKGLVHRILEEAERLRLHDPRLTPWIEQLTALARGYQTRKLREFVGAYAEGGADRIDGRAAPQGPA
>NC_021658.1|WP_020736732.1|6760540_6761674_-|acyl-CoA-dehydrogenase-family-protein
MSPASPTPPVGADAIALLERARELAARVLAPAANTTDQADSVPREHLRALAGAGLLGIATPARYGGLGAPARVAREVLEILAGACGVTAFVQMQHATAACPLIARGDNEALKERVLPRLASGERLCTVGFSHVRRPGPPMVRIEPDGDDVRLHGTVPWLTGHGIADDAVIAGTLPDGRLMYVLTPLSAGDSIEASPPLRLSAMNASATVSLTLRALRVGPEQVIATATREQQAARDVAGLLTPAALSLGAAGAAAALLASLAERRGEAQLAGAARALEDEREAARAEVNAWADQPEAEGYAEHAVRARASCVELGVRAAHAAVAATGGSANRLDNAAQRLFREAMLYSLTAQTRDLQAATVQRLLGRGAGAMDRARP
>NC_021658.1|WP_044986119.1|6762103_6763222_+|hypothetical-protein
MARLRFVTRFCAAIAAAWLPVIACSASGGGNGNTTGNGEGGQGASGPGAVSSSSGDDFGGEIGLTSSGPGGEPPADAGHQTTCDDEGNCTCINIASIGHEGVWGPCSSDSTTALQNWLNTQSTAQVDNYNMEKPTLTPEFLAKYDVILLQWMVTKGAQNDDGQPWQFSPDEVKALEDWVNGGGGLIALSGYQCNGQGCTIHDITATNQLLSFTDIQFNADGVLDPARTNCANCNCWGGPVPLGGPLPGSVGTWNQDTPIGKDIQSVGAYIARSIKSTTATVDCTDGTNNFAVHKEVGKGHVVAYGDEWVTYSGQWLGTAACLNSQMYTDPNSPCYERSAAQVFQISQFWYNALKYAASSIECFTIEDPAIIK
>NC_021658.1|WP_049949597.1|6763316_6764951_+|amidase
MKKHERPGGAWIAAILLGVVLGSPGDAGAAAGPVCAHHIDVTELTISKIQKAYRNRHYTAEALTQAYLDRIEQYEPSYNAFTFLNPSALDEARAIDRKRRNGEPLGPLAGIPVVVKESMDVVGLPSTAGWAPLSAEAGGVDLFPIENAVVVERLIRAGAIILGKTNIPAFSDDGTRANSSWAGPTYNAVDRDLAPGASSSGTATAVAASFAVLGLAEETGGSIQNPAAAQSLVGVKPTFALVPTAGIVPLAGSTRDVAGPIAKTVLDAALVMDVLAGYSPEDPKTSASDGRLPPHGYTSELSKNALRRKRIGLYGPGFRSSALSPETEDLYARAVLELERQGATVVDDPFAGSGFAELALPGEPYDMRGTESLAHDFQRYLAGLTFDGGVVGSIDELSLIAGISPFQEDGGPLFWYVEKLPVLADSLLHPEAPPDLSSFWALRGQYLSLFDAVMAEHDLDALAFPQTYEVIPELFSADTYAATTESAINIAGLPGVVVPAGQYENGAPFGLIFVGPLWSEPRLLGYAYDYEQATRHRIEPELTP
>NC_021658.1|WP_020736735.1|6765059_6765767_+|DUF4336-domain-containing-protein
MLRTIAEDVWAYEKDFRMPVGYLPARATVVRRADGGIVLHSPLAFDDATAQAIDALGEVRAIVAPSRLHHVFVKAATERWPRASVLGAPGLEKKLSGVPFAPLPRSGAAPELGDELTVRLVEGVPYITEHVFLHARSRTLIVTDLLFNVHEVRSFGMKVFLWLGGAWKKTAQDHVWRVLVRDRAAAARSVADVLAWDFERIVVAHGDVIEGDAKDRARRALAWMGGGAAPLLPAT
>NC_021658.1|WP_080682256.1|6765914_6768629_-|RICIN-domain-containing-protein
MRFASRQLLLAAATGLLAVSCVGLAEDYEDEEGGVLDEGLTIDPSAVYTMVGVQSNKCVEIRGGSTASSAAAQIASCRDGDTSQQFRVESAGSNYYRLRNVKSGLCLGVNGSSTSNGATIVQSSCGNATSQQFSIADVSSTAQRLTNRASNKVLDVMGRSTADGASLHQWNWANGDNQKFSLKAVGGSSSSSSSSTTTTSTTTTSSSSTTGTGGAGGTGGAGGAGGAGGAGGTGGGTGGSGDVGVAPASGCGLGYSQLPNGKGGLNVEPVCIPKEMNFNMAASLEAFKTTVYPLLQANCSGCHSSTGKAQAPLHSDVDPALAHEYALTRVNFKKPADSKLVVRMGIDRHNCFGSSCRDANTQMLSAVTAWANAVSSSLPTTPRPVAAGEQVTEAQVKSWIATDKATIPAADAEFIKYASLHEIHNKGATAEEMNVARVGLSKALNSTARWAPRIVNPVDINGKGIVYRFDTRSYWGYNKGVTKLHFGGSDDDVFFGRTSVNYLGEPVGSDVTFREKYRYTADVQVDPSFARLVWGRVLAGNVEGATDGGVLPPYVDGFKTDYIEASQLVYTLTRPDVYNAIMAIPWYAQDLESELGVIKDQGMKSYEYMLTKQAITVDSRMYWRAKTRRGGYYWKTFDVFTGQLDGGVNTIEQAWETGQIRFPFWAHPIPKFISGTGIGGSANNWSFVATLAQPQGTEPPGCDGQPSYAGGGYVNCRYYTGTDGLQQSAEEVIWDLPNGLQGYSLWGGFNQRRVDAFVNIVRDPRIQRNASDAQINSTVGFATQDRRLNTGSSCIGCHADGMNRGNNDLRDWLDAGGERLPKGEHGVDGWINDAAVVSQVKELYPPSSVMRSRMEDDRRVFLAAMAKIKSEMVLGADKNVYVEPTIWTIEWAQNFYKYAPTRSN
>NC_021658.1|WP_020736736.1|6769618_6769951_-|YnfA-family-protein
MRAALLFLAAGLLEIGGGYLVWLWLRDQRGALLGLAGFAALAAYGVIPTLQAAEHPFGRVYAAYGAVFIALSMLWGWGVDRKLPDRRDWIGAAICLVGAAIMLWPRAPRR
>NC_021658.1|WP_044986120.1|6770175_6770523_+|hypothetical-protein
MKIHLISLVIGALALGGAACSKEAPGAGKGATEQAAGAAQAHANAAHAPKDVKPGSHEDWCGEHGVPESQCSRCNPELIPAFKATGDWCAEHGLPESQCLKCNPGLKIVRPPKES

Crispr_ID: NC_021658_25

• CRISPR_ID: NC_021658_25
• CRISPR_location: 7376707-7376805
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_25

Consensus_repeat	Method
TCTCGTCGGGTCTCTCGTCGGGTC	CRISPRCasFinder

spacers of NC_021658_25

>25.1|7376731|51|NC_021658|CRISPRCasFinder
TCGTCGGGTCGTCGTCGGGTCTCGTCGGGTCTCGTCGGGTTCTCGTCGGGT

CRISPR arrays and Neighbor proteins around NC_021658_25

CRISPR arrays

The CRISPR arrays of NC_021658_25

>merge|NC_021658|25|7376707-7376805|CRISPRCasFinder
TCTCGTCGGGTCTCGTCGGGTCTCTCGTCGGGTCGTCGTCGGGTCTCGTCGGGTCTCGTCGGGTTCTCGTCGGGTTCTCGTCGGGTCCCGCGCAGGCTT

>NC_021658|25|21|7376707-7376805|CRISPRCasFinder
TCTCGTCGGGTCTCGTCGGGTCTC	TCGTCGGGTCGTCGTCGGGTCTCGTCGGGTCTCGTCGGGTTCTCGTCGGGT
TCTCGTCGGGTCCCGCGCAGGCTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020737053.1|7367717_7368944_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226984
NC_021658.1|WP_044986169.1|7379226_7379895_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737055.1|7372936_7373530_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_021658.1|WP_020737054.1|7368979_7372840_-|isoleucine--tRNA-ligase	unknown	unknown	gnl|CDD|235681
NC_021658.1|WP_044986170.1|7382274_7384035_+|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NC_021658.1|WP_020737059.1|7376829_7378068_-|glycosyltransferase	unknown	unknown	gnl|CDD|340831
NC_021658.1|WP_020737066.1|7383976_7385026_-|biotin-synthase-BioB	unknown	unknown	gnl|CDD|215219
NC_021658.1|WP_044986168.1|7375325_7376600_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340828
NC_021658.1|WP_044986167.1|7361910_7364484_-|hypothetical-protein	unknown	unknown	gnl|CDD|237171
NC_021658.1|WP_148313874.1|7374898_7375246_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737050.1|7364617_7365310_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|223620
NC_021658.1|WP_148314876.1|7380846_7382058_+|HRDC-domain-containing-protein	unknown	unknown	gnl|CDD|176654
NC_021658.1|WP_020737051.1|7365317_7366538_-|hypothetical-protein	unknown	unknown	gnl|CDD|226984
NC_021658.1|WP_148314877.1|7379989_7380850_+|matrixin-family-metalloprotease	unknown	unknown	gnl|CDD|334067
NC_021658.1|WP_020737068.1|7386965_7387745_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737056.1|7374256_7374868_-|thiamine-phosphate-synthase	unknown	unknown	gnl|CDD|238317
NC_021658.1|WP_080682290.1|7367098_7367731_-|DUF4276-family-protein	unknown	unknown	gnl|CDD|379470
NC_021658.1|WP_020737060.1|7378323_7379106_-|thiazole-synthase	unknown	unknown	gnl|CDD|234687
NC_021658.1|WP_020737067.1|7385655_7386708_-|PilT/PilU-family-type-4a-pilus-ATPase	unknown	unknown	gnl|CDD|225364
NC_021658.1|WP_020737069.1|7387769_7389167_-|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl|CDD|376689

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020737053.1|7367717_7368944_-|AAA-family-ATPase	gnl|CDD|226984	COG4637, COG4637, Predicted ATPase [General function prediction only].	1.39397e-27
NC_021658.1|WP_020737055.1|7372936_7373530_+|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	1.69799e-35
NC_021658.1|WP_020737054.1|7368979_7372840_-|isoleucine--tRNA-ligase	gnl|CDD|235681	PRK06039, ileS, isoleucyl-tRNA synthetase; Reviewed.	0
NC_021658.1|WP_044986170.1|7382274_7384035_+|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	8.65388e-50
NC_021658.1|WP_020737059.1|7376829_7378068_-|glycosyltransferase	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.40656e-73
NC_021658.1|WP_020737066.1|7383976_7385026_-|biotin-synthase-BioB	gnl|CDD|215219	PLN02389, PLN02389, biotin synthase.	2.21588e-161
NC_021658.1|WP_020737060.1|7378323_7379106_-|thiazole-synthase	gnl|CDD|234687	PRK00208, thiG, thiazole synthase; Reviewed.	3.394e-167
NC_021658.1|WP_044986168.1|7375325_7376600_-|glycosyltransferase-family-4-protein	gnl|CDD|340828	cd03798, GT4_WlbH-like, Bordetella parapertussis WlbH and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.	1.92603e-113
NC_021658.1|WP_044986167.1|7361910_7364484_-|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0.000390958
NC_021658.1|WP_020737050.1|7364617_7365310_+|HAD-family-hydrolase	gnl|CDD|223620	COG0546, Gph, Predicted phosphatases [General function prediction only].	6.54807e-30
NC_021658.1|WP_148314876.1|7380846_7382058_+|HRDC-domain-containing-protein	gnl|CDD|176654	cd06142, RNaseD_exo, DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins. Ribonuclease (RNase) D is a bacterial enzyme involved in the maturation of small stable RNAs and the 3' maturation of tRNA. It contains a DEDDy-type DnaQ-like 3'-5' exonuclease domain possessing three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific YX(3)D pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. In vivo, RNase D only becomes essential upon removal of other ribonucleases. Eukaryotic RNase D homologs include yeast Rrp6p, human PM/Scl-100, and the Drosophila melanogaster egalitarian protein.	1.1271e-45
NC_021658.1|WP_020737051.1|7365317_7366538_-|hypothetical-protein	gnl|CDD|226984	COG4637, COG4637, Predicted ATPase [General function prediction only].	1.22498e-09
NC_021658.1|WP_148314877.1|7379989_7380850_+|matrixin-family-metalloprotease	gnl|CDD|334067	pfam00413, Peptidase_M10, Matrixin. The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis.	2.14702e-18
NC_021658.1|WP_020737056.1|7374256_7374868_-|thiamine-phosphate-synthase	gnl|CDD|238317	cd00564, TMP_TenI, Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5- (beta-hydroxyethyl) thiazole phosphate to yield thiamine phosphate. TenI is a enzymatically inactive regulatory protein involved in the regulation of several extracellular enzymes. This superfamily also contains other enzymatically inactive proteins with unknown functions.	6.28895e-43
NC_021658.1|WP_080682290.1|7367098_7367731_-|DUF4276-family-protein	gnl|CDD|379470	pfam14103, DUF4276, Domain of unknown function (DUF4276). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 224 amino acids in length. There is a single completely conserved residue E that may be functionally important.	3.49045e-10
NC_021658.1|WP_020737067.1|7385655_7386708_-|PilT/PilU-family-type-4a-pilus-ATPase	gnl|CDD|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	2.57478e-124
NC_021658.1|WP_020737069.1|7387769_7389167_-|phosphomethylpyrimidine-synthase-ThiC	gnl|CDD|376689	pfam01964, ThiC_Rad_SAM, Radical SAM ThiC family. ThiC is found within the thiamine biosynthesis operon. ThiC is involved in pyrimidine biosynthesis. ThiC participates in the formation of 4-Amino-5-hydroxymethyl-2-methylpyrimidine from AIR, an intermediate in the de novo pyrimidine biosynthesis. Thic is a member of the radical SAM superfamily.	0

Protein sequences

>NC_021658.1|WP_044986168.1|7375325_7376600_-|glycosyltransferase-family-4-protein
MRVLLITKIFPNAVHPDEAPYNRRQFAALSRYCDVRVLATIPWFPGIERLSKWPVGASAPREEVIDGLPVRHPRYLYVPRVAPALNGPLYAASMLPELVGRGPSPDVIVGAFAYPDGFAAVCLGRLLRVPVVIKVHGSDIDVIPRDARLRRPLSWGLTRATRVVAVSRKLADGVAALGVPRERIDVVMNGVDAKLFQPRSRAESRAALGRSPGSKMFVFVGHLNRDKGVLDLVEAFERIAPAHPDLELTLVGSGAEEEACKAAAARLGGRLTVTGYLPHDQVSLWLGASDALVLPSLHEGTPNVVLEALASGRRVVGTSVGGIPDILHSPELGELIPPGDKGALADALLRAARHEYDPARVAELAGGRDWDDSARALHDTLLRAVRGARRPSAGGQDLGDAPFSVPGPKGGAENGAARTGAPLS
>NC_021658.1|WP_148313874.1|7374898_7375246_-|hypothetical-protein
MTLARVHRRMAPVLPGIRAALGPLVIFAAVARAPYQCASDVDPDHRQYEDPSEALYGLAERFKANGDRRAQADTLRFLVERYPSSRFARMARQDLEALGEPGAPGGARAPGDGDR
>NC_021658.1|WP_020737056.1|7374256_7374868_-|thiamine-phosphate-synthase
MLTPRLTLITQTADVPEPALLARLSAFGALPPEARARVAVQLRDPELSGAALHALGRRLRDATAALGASFVVNDRLDLALLLGADGVHLGRRSVAVADARALLGAGVFVSVACHGVDEVLRAAEAGADAAVLSPIFATPGKGPPLGLASLGEARARLAAASRGVALIALGGVDAGSAPACLAAGADGVAAIRADFSGALPAPR
>NC_021658.1|WP_020737055.1|7372936_7373530_+|Uma2-family-endonuclease
MSAQHPLFPGNAPEVETAFQAVPEEMVAEILDGELHTFPRPARPHTRTASRLNVRLGGPFDLDPGGPGGWVILVEPELHLGPRPDKVVPDLAGWRRERIPDALGPDDAPAHYDLAPDWVCEVISPRTERIDRGKKMRIYRREGVRHAWLINPVAQTLEVYRLDDGRWSLLDTHEGDEAVRAEPFDAIELPLADLWAR
>NC_021658.1|WP_020737054.1|7368979_7372840_-|isoleucine--tRNA-ligase
MSEASSKKPTDGPHEPLFDKVATELNFPADEAKILAFWKQHRIFEKTLRAETRATGPSKGTFVFYEGPPTANGMPHNGHVLTRAVKDVFPRYKTMRGYDVPRKAGWDTHGLPVEVEVEKELRIHGKADIERYGVEPFISRCIDSVFRYTEAWESLTDKIGFWVDLDSAYVTYHRSYVESVWWALSQLHKKGLLYRGHRVCWWWPQGGTALSAAEVGWNYKTVDDPSVFVAFPLVDEPDTALCAWTTTPWTLPSNGYAAVRPEFDYVVVDAGAPAGGAAQVARKLIVAAALREELAKKFKRDLPVLRELKGSELIGKRYRPPFDSYSRSLEGASLRRKDGKEEPLYWVVIGADFVTLDSGTGVVHIAPAFGEDDFNAHKRRVAELAAPGAAGEVPILCAVRPDGTFEPGLTPFSGLWVKDADPLILKDLAARGLLVHDEKYRHDYPFCWRADDDPLIQLARPAWYIRTRENIDKAIANNRAIHWMPPHIQEGRFGDFLANNVDWALSRERYWGTPLNVWICANSEEHQLAPASVAEIEALNPRAFDHFHEAKKADPSLNDHLIVHKPWIDRVTFPCPSCGGEMRRVTEVIDAWFDSGSMPFAQWGYPHAPGSKELFDRAFPADFISEAIDQTRGWFYSLLMVSTLVFDEATQEKLGLSRARSYPHPYKTCVVLGHVCDREGKKESKSKGNYTPPEVILERVRMEFAAVRAAEVKGAQPKDGVALIAREDYEGLDLTGDAAKVRMYRADREAQPITMELRPQKGMPRRIVALSEADLDRLGLTPGQGALSVMPNDVPRLDQAERVTIEDPSTSAPGADAFRWFFYASSPPWTNTRHSLTNVRALQKEFAVKLRNVYSFFTIYANIDGFSPAEGNPGAADTSPAALAASAGYRPAKERSLLDRWILSELALSTREVTAHLDEYRLYEAAQRLVDLVDALSNWYVRRSRARFWAATAADPLDVAPGAVRAAQDKRDAYFTLYEVLVAIAKLSAPFTPFLAEAMYQNLVRRPWSASQPESVHLVAFPEADPAAVDEPLAVEMRAVRELVSLGLQVRTANKLKVRQPLARADVVLSQQGLAAALAEHVPLIAEELNVHEVRFLKPGEEGSAVRYVLKPNFRALGPKLGKKVQLAKQVLAKADASALRAALATEGKIAIALDGEQVELGPEEIEVAVEAGEGFAAAGGRAGVVVLHTALTDALRDEGLGREILSRVQGLRKELDLGFTERIRLALDGSERARKVAGAAREILMQEALAAELVLGAAPAAWGQAERRELSVDGEALAIAVARTA
>NC_021658.1|WP_020737053.1|7367717_7368944_-|AAA-family-ATPase
MITKVFARNYRSIGEVELPLAELTTLVGPNASGKSNIVDAVRFLADCLRAPLSFAMTMHQRQGFGSLLHQGDTASLGLTVGAEVHTHGGLGIWAFTLQPAGGDGGFEVKSERAAWVQGGTPGTWAAEELEKLLRLEEVPDLQAALRSQHGSGFVRFGGLHVSKVGDILGLLSPPTHTALALPQVSDEALRPLADELNRVAMYSLFPNELRPPRAPNPEKPMMANGENWAWTLSSLDKERWGGELLCSLSRIAGDVDDYRVVRAGGYLIPEFRHGVDASGDGRWRGAAQESDGTLRVSAILTALFQEPPLSLIGIEEPELAVHPGALPILFDFLREASRRSQILLTTHSPDLLDLLPVDSLRVVERRGGATIVSRVDERQRELVRKRLMSTSDLLHAEGLHPEGIDDDG
>NC_021658.1|WP_080682290.1|7367098_7367731_-|DUF4276-family-protein
MTMGKAYLIVEGHGEVGAARNLVIRLWADLGLRHAVWGAPKRGKALNTRAGVLQACELLRSERDCSLALLLRDEDDGCPATAGPETAAWVTAASLPFPAAVVLAHREFEAWFLPCIHLMAGREIRPGVRIAEGTTCPENPESIRDVKGWLSERFPPGKTYKPTLDQLRLTQWIDFGVLRASQARSFRTLENALRFLAAPGALGVYPPPRP
>NC_021658.1|WP_020737051.1|7365317_7366538_-|hypothetical-protein
MITHVYVSNYGSIGPGIELTLGALTALVGPPGAGKGCLLDAVRFLAECANGALEQAAASRRGGGALQRPRDSGAVTTLGVAVSRTEGHGFWLVQLAPGDREGEPRVKSETAAWWQRSALTRLVKPGLRDVFDAGSDPPEVSFDRLKGSPKGFSRKDKGRSGTLAYRGVAPIAVSGARLVLPLLSDGPLTPMRDELRRAVLYSLAPRPLRSPQKISASRRLRASGENWGSVLRALEKERWSEQFLASLSQVLGDVDGARALSSGGFLVPELRHGVDDGGRERWRAATDEPDATLRLAAMVTALSQEPPLVLAGFEHPDAGVDRGALPALVEYLRGASAQRHLLLTTESPALLDLLPRESVYSVALRDGSTTASPIGEPERRALREQLVAAEGQRARDARSDRPPRGP
>NC_021658.1|WP_020737050.1|7364617_7365310_+|HAD-family-hydrolase
MASVSAVIFGVDGTVLDAVDLHAAAWQRAFARFGREVAREKLRRHVGEGADRLLPVFLSPEEIGWIGAGIAALHDEIYARELLPGARVFPGVRELFERVARDGRRIVAAASMSRGALDASLARAGVGDLVSWAVSADDAGRWKPHPDVLEAALDRLGSVDPREVVLVVDTPSGAEAAAKLGILAVGLRCGGFPEMELVEAGCAALYRDPEDLLARYDASPLAPERERLAG
>NC_021658.1|WP_044986167.1|7361910_7364484_-|hypothetical-protein
MNGRLPALSVFLGALLGPASSAAQDGPALIVVDRDDDDADGVPDAEQGRVPPSPELLALRAPRGASQAPAAIPDGLRLLVDGSPVQPGSAIPAGARRVELQAVRAGRSEIALFGRTLPISAFEVRAIDGAGTRIDMARSHASLQRTPPDRLGDDPFGNLDDPDAIRLLVIGAAEDLPLTVDVHSAAPSGRAIDRLPSVPLGHVACPPDVPAGLVCGSTRPLRVVADDIDRNHPMIADRSVKGEVGGALVVALPDGPKLQMIRIAGPRASPLGPLGRTRARLRIFMVRPRAGGPPPMGGDDSGALAIARAEVERANALWGACGVSFGPPEELDISFVDPPRPHLLAIGCDHGLPASGGAIRVRVDGREVTAAIRPRMRPDAAARAVAAAIGAAGFSVRLSDNPAIGAGAFGTTDVLVRRPGGAPAAIEPPASGALSTDPTLTACIGAVELEDGLQHFSDTDAIAGTVEERALIKAFDDGDPATIDVVMVPSFAGGGRIGESFIFADGGAIRNTIIEDRAGLRADRASFALSHELGHVLLDEPGHPDDFGVDTPTRLMDADAANSSAYGPRRLTVDECVRAIRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGRQSGASEPRLGKQSGASEPRLGRQSGASEPRLGKQSGASEPRPGGQSRAADPRLGEPPPRGAKVDPAGAAAASPPGAPGFRPSGPVPLLAPWPLAPLGRER
>NC_021658.1|WP_020737059.1|7376829_7378068_-|glycosyltransferase
MSKPNVCMVVNNLEVGGLEKVVLSLLDRLGDQGFDLSLICLDGEGRLFSEVKLPRSKCLVITKDLRPVLPGLKSDPEAILWIRRFFHQRSVDIVHVHNRAPLIFAGLAARLLRNRPLVVYSEHNQINRAKGFDRRKFGYYAYLADEMVAVSHDLKRILVDDVKVRAPVRVIHNGIDGTRFARALTSGQQGRIRAELGIGEQEFVFGCAVVHIEQKGLRYLIEAAPEVLRRAPEARFVVAGDGPLRGELQQRARDAGLGDRMLFPGYRSDVPELVSAFDAYVLPSLWEGLPLALLEALALGKPIVASRVGGVPEIIEHGVDGFLVPPKDPGALVEHLSRVARDPELRERARTRGPAKFAEQFSLEAMVDAHVRLFDELVARRRGGEASPRAQRSGGTSQGPVVNTRLSETDRA
>NC_021658.1|WP_020737060.1|7378323_7379106_-|thiazole-synthase
MTSDALTIGRHTFTSRLFVGTGKYKDLEETRRALEASGAEVVTVALRRVNLKERGEGSMMSLLQQGRVTILPNTAGCYTVEDAVRTCRLARELGLSDLVKLEVIGDERTLFPDNEATLEAAKILVKEGFTVLPYCMDDPIVCRKLEDIGCAAVMPLAAPIGSGLGIRNPYNLMIIRETAKVPVIVDAGVGTASDAAVAMELGCDGVLMNTAIAGARDPILMAQAMRDAVRAGRMAYLAGRMPKKLYATASSPEHGKIAGL
>NC_021658.1|WP_044986169.1|7379226_7379895_+|hypothetical-protein
MSPRALLIALLFALPPAVTLAPGGDADPAAGVSPGALLSGPRAAQAAVAVQLSLDELVAAASYVVVATATEQHSRWEELGGAERIVTYTRLSIDRTVAGQPDADVWVRTLGGIVGDVGQHVAGDAQLRIGAQAMIFVSRASSALVVSGMAQGHYPIVDAEETRRIAGAPRIAVRRLAASPSSGTVLARPGPAISAREQLVGATVDAAIDAVSRAWKAKHAQK
>NC_021658.1|WP_148314877.1|7379989_7380850_+|matrixin-family-metalloprotease
MAYCRTSVCPETQSTAAVCNPQQATDCGIPLAWPSPCVSYSLQEDASDQVTLAEAEAIFEQAFATWTAADCGGGASPRMEVTYLGPISCDAHEYNQRKGNANIITFRDDGWPYGSGGNTLALTTVTYNLKNGEIYDADMEVNSFDVTLSMGDDDVSFDLLSIATHEVGHFLGLSHSAEVTATMYADYRPESTMLRDLDDDDRAGICSVYPPGEPVEACDPTPRHGFSDLCAEDQPDREESGGCAAAPSSPGGGSGGGLLAAAAASLGALARARRGRAARPGRERAR
>NC_021658.1|WP_148314876.1|7380846_7382058_+|HRDC-domain-containing-protein
MSQAPPVLVEREGDLARVVERAARADALAVDVEANGLFAYRARLCTVQLAFREGDGVAVAVVDALRAPVAPLAPLLGAAGPPKVLHDLTFDARMLAEAGAPLAGARDTSVAARMLGRAATGLAALVSAELGVKLDKQLQQHDWGRRPLADAELRYLADDVLHLLPLDARLAEHGRALGIEDEIAEECAYKLATALGPPRDPRPAYARIKGAQALAPEGRAILRRLVLAREAAAEEADLPAFKIVAGEVLLELAQRRPARADDVRAVRGAAAGRAGSLVAAWLRAIEQGRDDGDVPEDERALFAQPRPSRREIAVRRAMETRIAAWRRAEAKARQVDEQVVLPGHCAQDLVEIALAGGRAGGGAVADAIARIPGLGARRLARYGAALAALVTAAMASEPPAAAV
>NC_021658.1|WP_044986170.1|7382274_7384035_+|mechanosensitive-ion-channel-family-protein
MRWNDPPEGSKRRRLLPAAKWWIRAALAFALVFGCVLLGASAGELSPPPPPSAPPAAVSAEAGVDPETIPVAPDSPRASMSAFLELCRAGEYAEAARFLDLPPRADGAAFAQKLKAVLDRHDWLDLERVSPHSQGDTQDNLGAGVEQIAKIPTRTGYQPVRLVRRTTPDGVRWIFSRATVERVDDWYARLEDRWLRDHLPPALLRPGPRELLWWQWLALPVFALAGWLVGAVLSFALRALLRRLVVRTESPLDDALLEGTRGPLTFAAALLAIEIALPWLGLYAPAEAFLDKVVRAGVFVAVFWFALRAIDAVGGRLLAAPATRDNPAARSLVPLMGRIAKVAIVIVGAIAVLSELGYPVASLIAGLGIGGVALALAAQKTVENLFGSVSIGIDRPFQVGDFVKVDALLGTVETIGLRSTRIRTLDRTIVTIPNGKLADLQIESYTARDRMRLACVLGLVHETTPEQLRAIIEGCERALRAHPKIWPDDVVVRFIGVGPSSLDVEVMAWFQTTDFGEFRTMRQEMLFSFLELIASAGSRLAHPTQTLHVATRDGARPRPEAADGGGPANGRREPRPAPSAGAPPSR
>NC_021658.1|WP_020737066.1|7383976_7385026_-|biotin-synthase-BioB
MLDGIERDAAGHNGGRKEPNGSAPAAGGVRHDWTVEQAVALHDLPLFELIDRARSVHRAFHGEHEVQLCTLLSVKTGGCPEDCAYCPQSSHYETEVGPERMLDVGAVLAAAERARAGGSTRFCMGAAWREVKDGPAFERVLDMVRGVKGLGLEACCTLGMLTDDQARRLKEAGLDAYNHNLDTSRKAYKSIISTRTYDERLVTLRNVRRAGITVCSGGIIGMGESIADRCEMLVELARLDPHPESVPINALVRSPGTPLESLPPVDPIEFVRMIAVARLMMPRAMVRLSAGRTELSREAQLLCMYAGANSIFYGDKLLTTPNPGPDEDRALIEKAGLQPMAPAAAPAAR
>NC_021658.1|WP_020737067.1|7385655_7386708_-|PilT/PilU-family-type-4a-pilus-ATPase
MTTPYTSEAFIHQLLGKALAAHASDIHLKVGQPPGARVRGDMVYFRVDRIRPEDSEAAARVLLAGRPSRELLATLQELDTAYVVPGLGRFRVNIYRQRGSLAIVLRSIPLKIPTFEELGVPSAVRAMVEHDHGLILVAGTAGSGKSTTLAAFIAQINATLPRHIVTLEDPIEHVHEDNRSSISQREIGVDTSDFPTALRSALRQDPDVVMLSALRDGESLDLALHAAETGHLVLAAVHTPDVARTLGRLVALGKSPSEVRDRLADCFQGAVAQRLLPRRDGAGEVLASEVLVATAAVREAIRRPEGSSSLRELMEKGVTPYGMQTFEAHLRQLVGQGAIAKETAKAVTAL
>NC_021658.1|WP_020737068.1|7386965_7387745_-|hypothetical-protein
MRRGRGRAGLPRAPAGGRASARPRAGLVASPTPRLGRPVRVAPLSLRLARAVLVASLALVVLGPLACRGERAISTSAASSASSPAASLSAAPRPPSPRLTDPRWRLAAGDDPLERARLAEAEGATGLLAALEDGGDIALTALGALPYADDADLALAPLAERARAASGPSLTPLLEALLGIAGRPPRPREPLDPDGARAAAAALVELSGRRGLPAEQRALAISAARALAEKGLVDPRDIPADLDPAGPDAGSAGAQAPRP
>NC_021658.1|WP_020737069.1|7387769_7389167_-|phosphomethylpyrimidine-synthase-ThiC
MLRTEWVSKRAGSPNQSQMHFARKGIVTEEMEYVARRENLAPELIRSEVARGRMIIPANKNHLNLEPMCIGIASLCKVNANIGNSQTTSDVSGELEKLRYAIKYGADTVMDLSTGGDIDGIRRAIIADSPVPIGTVPIYQALEACKGTEKMTAADLIDMLEHQAKQGVDYFTIHAGVLLEHLPLVKGRITGIVSRGGSIMAQWMIEHHKQNPFYTHWDKVLEVCAKYDVTISAGDGLRPGCLHDASDAAQFAELKTLGELTKRAWEKDVQVMIEGPGHVPFDQIAMNVQKEMELCHEAPFYVLGPLVTDFAPGYDHITSCIGATMAGFAGAAMLCYVTPKEHLGLPNPEDVKQGLIAYKIAAHAADVARKRPGARDRDDALSRARYAFDWKKQFALSLDPETAQAMHDETLPQEYFKTSEFCSMCGPKFCSMHINRVVDEYNARQDRQETENAPTKRSLSLIDQP

Crispr_ID: NC_021658_26

• CRISPR_ID: NC_021658_26
• CRISPR_location: 7538290-7538389
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_26

Consensus_repeat	Method
CGCGGCGCGCGGCGACGACGACGACGCGCCCCG	CRISPRCasFinder

spacers of NC_021658_26

>26.1|7538323|34|NC_021658|CRISPRCasFinder
GCGCCGCGCGCCGTCCCGCAGGTCCTGAGCGCGG

CRISPR arrays and Neighbor proteins around NC_021658_26

CRISPR arrays

The CRISPR arrays of NC_021658_26

>merge|NC_021658|26|7538290-7538389|CRISPRCasFinder
CGCGGCGCGCGGCGACGACGACGACGCGCCCCGGCGCCGCGCGCCGTCCCGCAGGTCCTGAGCGCGGCGCGGGGCGCGGCGACGACGACGACGCGCCCCG

>NC_021658|26|22|7538290-7538389|CRISPRCasFinder
CGCGGCGCGCGGCGACGACGACGACGCGCCCCG	GCGCCGCGCGCCGTCCCGCAGGTCCTGAGCGCGG
CGCGGGGCGCGGCGACGACGACGACGCGCCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_044986187.1|7524657_7525809_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080682753.1|7528066_7528795_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737180.1|7540374_7541100_-|6-phosphogluconolactonase	unknown	unknown	gnl|CDD|376480
NC_021658.1|WP_020737170.1|7525805_7528070_-|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_021658.1|WP_020737174.1|7531997_7533482_-|cation:proton-antiporter	unknown	unknown	gnl|CDD|366411
NC_021658.1|WP_020737183.1|7544262_7544607_+|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|225291
NC_021658.1|WP_148314879.1|7521655_7522735_+|endolytic-transglycosylase-MltG	unknown	unknown	gnl|CDD|376862
NC_021658.1|WP_044988756.1|7531354_7531969_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_021658.1|WP_020737179.1|7539556_7540231_-|cobalamin-B12-binding-domain-containing-protein	unknown	unknown	gnl|CDD|227345
NC_021658.1|WP_044988759.1|7542195_7543773_-|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|235579
NC_021658.1|WP_187345634.1|7551797_7553660_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_148314880.1|7550389_7551097_+|1-acylglycerol-3-phosphate-O-acyltransferase	unknown	unknown	gnl|CDD|153251
NC_021658.1|WP_080682754.1|7533493_7534798_-|cation:proton-antiporter	unknown	unknown	gnl|CDD|223551
NC_021658.1|WP_148313890.1|7541122_7542298_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	unknown	unknown	gnl|CDD|378404
NC_021658.1|WP_187345633.1|7546523_7550294_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020737167.1|7523572_7524643_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737164.1|7519716_7521291_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238742
NC_021658.1|WP_020737172.1|7530588_7531248_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_020737178.1|7538405_7539566_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_021658.1|WP_020737184.1|7544891_7546160_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_044988759.1|7542195_7543773_-|glucose-6-phosphate-dehydrogenase	gnl|CDD|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NC_021658.1|WP_020737180.1|7540374_7541100_-|6-phosphogluconolactonase	gnl|CDD|376480	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.	7.76182e-69
NC_021658.1|WP_020737170.1|7525805_7528070_-|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00885601
NC_021658.1|WP_020737174.1|7531997_7533482_-|cation:proton-antiporter	gnl|CDD|366411	pfam00999, Na_H_Exchanger, Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.	3.78992e-10
NC_021658.1|WP_020737183.1|7544262_7544607_+|DUF433-domain-containing-protein	gnl|CDD|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	5.53251e-12
NC_021658.1|WP_148314879.1|7521655_7522735_+|endolytic-transglycosylase-MltG	gnl|CDD|376862	pfam02618, YceG, YceG-like family. This family of proteins is found in bacteria. Proteins in this family are typically between 332 and 389 amino acids in length. This family was previously incorrectly annotated and names as aminodeoxychorismate lyase. The structure of YceG was solved by X-ray crystallography.	4.16067e-84
NC_021658.1|WP_044988756.1|7531354_7531969_+|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	1.21075e-27
NC_021658.1|WP_187345634.1|7551797_7553660_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.41799e-100
NC_021658.1|WP_080682754.1|7533493_7534798_-|cation:proton-antiporter	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	3.90522e-10
NC_021658.1|WP_148313890.1|7541122_7542298_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	gnl|CDD|378404	pfam10128, OpcA_G6PD_assem, Glucose-6-phosphate dehydrogenase subunit. Members of this family are found in various prokaryotic OpcA and glucose-6-phosphate dehydrogenase proteins. The exact function of the domain is, as yet, unknown.	4.35928e-29
NC_021658.1|WP_187345633.1|7546523_7550294_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.26143e-68
NC_021658.1|WP_020737179.1|7539556_7540231_-|cobalamin-B12-binding-domain-containing-protein	gnl|CDD|227345	COG5012, COG5012, Predicted cobalamin binding protein [General function prediction only].	9.3531e-14
NC_021658.1|WP_020737164.1|7519716_7521291_+|VWA-domain-containing-protein	gnl|CDD|238742	cd01465, vWA_subgroup, VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the VWA domain in these proteins. The members do have a conserved MIDAS motif. The biochemical function however is not known.	2.32137e-39
NC_021658.1|WP_020737172.1|7530588_7531248_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	8.11084e-12
NC_021658.1|WP_020737178.1|7538405_7539566_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.36094e-43
NC_021658.1|WP_148314880.1|7550389_7551097_+|1-acylglycerol-3-phosphate-O-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	6.02783e-55

Protein sequences

>NC_021658.1|WP_080682754.1|7533493_7534798_-|cation:proton-antiporter
MNAIWLLMGLLVLSYLGSSLVGGRVLRGIGLPSGAEYVVLGFVLGPSALGLLEPSSLAAFEPVAGVALGWLAVVVGLDFGFVGNRRVRPSRMALGVLMSLLTGSAVAAAVWFAAARGAPSLESGDRVLLAAGVGAVSAETTRHAVLWVTQRYSASGKLSDLIADIADCDDLGPLLMMGGAFALVPQATGHWPLAFWGWTIVTALIGVVLGLIAVVLLGSDFRLIQSWGVLLGTSLLTMGTSARVGLSPLFATFAMGVTIAALSRHREEIVAMIAPTERPVILPALLLAGAQVNPKAAPFLPWIVAIALAARVLGKLATGLVFRVASPDARDTSPWLGLGLLSSGAVAMSVGLAFALRFPGPVGHTVLVAAAAAAVFGELVGPQALRATLRKAGELAAPERESLFFGRGLGRAARDAAPGDGDVPPPPVAERGEG
>NC_021658.1|WP_020737174.1|7531997_7533482_-|cation:proton-antiporter
MSAAALPDVAPVAPAGPDAPAGPAGPAAAPGPHGAPPSGHHGSAPKGPLNHLTHAVALVILFGVLYATTRAVPHDNGPAGTIASIGFLLLAGTLASELVEPLRLPHLSGYILAGILAGPHVLKLVDHHAVEEISRVNALALALIALAGGAELRLEMVKKSLRSLLLHNLVQTVLVFVAMTGVFFAARSLVPFAADLPIAAAFGVAILWGVIAVTRSPSAVLGILSQTRATGPVAMNTLAFVMTSDIIVIVVTAVALSTVRPLIEPGTTMSMHEIELLGREILGSISIGTTLGLALAAYMRLIGRQLILVFVALGFGATEVLRYLRFDALLVFVVAGFVVANLSKQGEKLVHAVEDAASVVFVLFFATAGAHLDLPLLKLMWPVALLFGASRAFVTWVASRIGNRLADDPPVLRKWAWCGLVSQAGLTLGISLTIERAFPSLGAGFRALVIGCVALNEVVGPILFKYALDRAGETAVEASRGSLPKSLPDLGRPG
>NC_021658.1|WP_044988756.1|7531354_7531969_+|Uma2-family-endonuclease
MTLPARPRRHATAADLLAIPEAERFHEIIDGDLVPKATPSWSHGRAQARMTARVSDPYDRPPGRRGPGGWWFVTEVEIALEPNQIYRPDIAGWRRERLAAPPTELPVRARPDWVCEVLSPSNASNDTVKKLRTYHRSQVPHTWILDPLHETLTILRWTEGGYLLVAAGGRGDRVRGEPFEAIELDVSELFGDEDEAGEPEKDDT
>NC_021658.1|WP_020737172.1|7530588_7531248_+|hypothetical-protein
MRRPAPLFLALSASLALAAAGCSSGATPPAERHAAPQAEALATAPASAAPPPTDPPAIAAASASAATAATPAPAASAPAAPDASASASAASAAAEPAAPASAPADAGPLPKVKVANIGMHIGGGPHDDFTKEPIKRSVAPHFDDFRRCFALAEDPTKGGDFGIDLRIEKDGGKAEVRKPRTALKGEAFTKCVVGVFERIDFLKPRRGPTVVSYSLRFTP
>NC_021658.1|WP_080682753.1|7528066_7528795_-|hypothetical-protein
MLAAAREASRAPNELAAEIMTLSAELQALAVSFDEAIAPHEEVLATHGAVVPDMTSGALRSLSAMLGYAQRRVARSDATATALIGGIALRRQALGVLERDEGAREGIARSRIERASEVFGEGARARVEALSAAPPVSEKLGLPLLAGRRGVLVALVQMRPLCEAAGSSWRETGCAALRGRFDAAEAELRTGLPRKIAAGLAALREKAMPAAALDAVQARLDAGDVKGAAMAYDAAVRGAEGT
>NC_021658.1|WP_020737170.1|7525805_7528070_-|hypothetical-protein
MRGSKEFARRGFCAAVFQKLIALMTALSVLAPSSTWARTRTPYTVLWRSYGDADSCGSTELETEGDAIFEVNRTPLPTYGVPGALQIHGDGSRSNTLEAEFDSVLLLMGRNGFHFGVHTVNGGNWCTHAQEVVHLVSGPLGLNKPLFDIRRDGTGFEGSTAVDLSLAEINPDLARDIAELEVRIARLMTELLRNAARVTDLRARMDLLRQLDTELHDLVSRPLDEISRTDLDAILDRYEDVVDAETRAAMEQLVDDLKKSVSDLESELARLLDEFGAQADEVADLATQDARAEGWDPDDPWNYALGESEVPWVEVPDIAEVEGAFDEGRDPYAAYADAVLAALEAAVSGYAGYADAVIAALEADVSGGVVVARADFVANVRAWRENSAALEIALRDRMGVSLAETNAFLKAQNRITAYVRRFMDASDWFVDTPVPADLRAVVDTVLKPRFDALADQMKDSLNQWTGDGLDLEQTQLYQTISAFAGAMSTVGEGVEAYAGVMQTLVHATTRIGVGFVPVVGPALDLCEAVSGKEFCLPSGRELSDEERIFSGLGFGLGAIGDVWRGVAAAGALPPTTIRIAGKIADVDDVLVKGFQVRRLRAYKTLRGAVTEQPLYPFEKTAAKFLSRDGRTLLGVGDDGVRATLWPKLARDARTKPRAPDFITVSAQNKLILSEVKGGVNIDGKEVIEQLSSGMEGVRQNGLVGDVEEVQLLMERGGKFGGTQFIAQDGYLFDTQKGKRATLKGFNMPIKVIRL
>NC_021658.1|WP_044986187.1|7524657_7525809_-|hypothetical-protein
MSTPGPRFYAWCDEASRVDALAAALSALARPGGFLDAWANFDVRCATKSMEAAVAMIRTQYPCTGTAHATCSTILPGAQRLALPDQRGPDSPAMRSILVDLQCFTEAYEPRWSLRGPHEPQGPLEMYPENCMHFFGFILELAWGRGPRSFEVEAELAWHLLQIDLEDLLLRLCEPDGSGRVRTGACTSAWRWHAPVTTCATYNACAREIARDLAVSWVHLHDKDSVSRIAGIPLSMLHARVDAAPRGARVAIAPPRGSRVARKGGGARACSLSRETVLKALAAPPSVLLDALEASAVPDNAWRAAAPRASEILERTRRLAETGDGPPTWPVDTDKHRHFRFLKKHPPFLVRRLASGGVVLATHPFCSLWPLWADALDALGLMG
>NC_021658.1|WP_020737167.1|7523572_7524643_-|hypothetical-protein
MRPGPYFYAWCDEASRVDALGAALSALVDHPPYTVGVDLCPGPEPHGASVDEAVATIRAHFRHADAEVVLHSTLSSRQFVRCMLRCFTDRSERSTSWGPLHLHPERVQDFAPMYMILDLGSGASSVGAEAVLAWHKVVTDIEDFLLRLCAPDASGRVSTGGCTTAWTWLAPVSMCATYHANARDIARDLALSWISLHDGESVPRIAGLSIDALYARVDAAPAGARVVPTDKSGRSIPLSREAVLKALALPGSALLEALIAAADVPDEVWRAAEPRAEEIHNLTVQAKARGEQLPESLKGPPLWYVEMTGEHVYFLVDHAPFHIRCLPSGGVMMATHFYRTLWPLWADALFRLGLMS
>NC_021658.1|WP_148314879.1|7521655_7522735_+|endolytic-transglycosylase-MltG
MLLGLAGAFAAAGAALLALVIGFGRTRAPDRGRVVEINWPEGLDAGEAASLLAAEGLVESERAMALYLGATGGTEGFVPGPHLLFEGATPRELRQLLTRAEGRPTAKVTIPEGWNRFDVAARLEKLRVAGRKTFLAATADGAFLDALGVERGGAVGAESAEGYLFPATYEFPLDTDARDVAKRLVAEADRRWSALAAESKDGLAALQATLGWGRREVLTLASIVEKEAVVAEERPLIASVFLNRLLDPTFRSRRLQSDATALYGCVAWPEEAPSCAEWGGKPTPAVVRDPRNRYSTYAHPGLPPGPIANPGGPSIAAVLAPAATKYLYFVAAGGGRHRFSESLDDHNDAVRKRREATAQ
>NC_021658.1|WP_020737164.1|7519716_7521291_+|VWA-domain-containing-protein
MKPTHVALFSALGMMFTSLSVYSLVPSGAAVEAAEVTAEPPPVVPEVTGGAVAAVDPSRFATGSRLMLEGRVGHARLPRSAQETFLMFEVRSDDAPARAQAQANLSLVIDRSGSMKGTRLANAVQAATTAVGRMNDGDVVSVVTFDTRTTVVVPPTTVGPDTRGRILAGVRGISLGGDTCISCGIEEGLSLLAQAGGGVSRMLVLSDGDANHGVRDLPGFRAIAQRARDRGVSITTIGVDVDYNEKILSAIALDSNGRHYFVENDAALARIFEAEAEQLTASVANGAELAIALAPGVTLDRVFDRSFRRAGDQVIVPLGAFAAGEVKTVLLKVRLGGLGDDARGASPIADVGLTYRDLVARTDARCEGKLGVAIADRDADASELDALVAGRVQRSETAATLKQANFLFEQGRLDEARSKLDAQQRSLRSAADKAKRAAPAGRAKDVASDFESQIAALERADTGFGAPPSFATPPPAAPAAPAKPGGFAQAPAAAPAPARPAPAQSREGKAAVRRNEADAFDLAR
>NC_021658.1|WP_020737178.1|7538405_7539566_-|HAMP-domain-containing-histidine-kinase
MAVTQPDAAALLGALLASEDDLLLVVQRGEITHASAAVERRLGGAAAGRDVAALFHEESREKLAAALGHEAPATWELQACREGEGQEPVRFLVVPAADGSRLLLGRAPARDEAVRIKEAAITLTTALADIARELATKGAELEAARAGLEELGRHRDELLSIVSHDLKASLHAIRLQGSLIEHAESPPTAAQRATIAGRLLRNVDRMTSLISDILDAALADAGELRIEPRRFSLGDVVAEVVDTVALIAADAGVQLRRAAAGAALVDGDARRLYQVVLNLVENAIRHSPRGAEVLIALEAQGARVRCSVEDGGAGIAPEERAAVFERFQRRGGRAGRAGLGLYIARRIVALHGGSIWVEAGARGGARFVFEIPAPGGAGGAEDAGAR
>NC_021658.1|WP_020737179.1|7539556_7540231_-|cobalamin-B12-binding-domain-containing-protein
MPSGEGRAASREPRIAEGDDAEARLFTAAILTGNYVAARSVLHAAIGNGLGYVYERIVVPAMDEVGRRWYENRISVADEHLATAVAQTAVASIYPLIQWPPGGPRAVVGYVEPERHVFGARMVADLLALDGWRTTFASGGISLARGLEDLRRSEVKLFAVSVTLGEHLPAARALIQRAREDVPGVKVLVGGRAVAALPDAVQLLGADAVAASASRAVEVARAWR
>NC_021658.1|WP_020737180.1|7540374_7541100_-|6-phosphogluconolactonase
MNGGEETLVAADAAELAILAAELMARAIAAAIEARGVARIALSGGGTPSEAYRRLAALSLPWAQTEWFWVDERAVAPDHPRSNHGAARRDLAAARIPEDRFFRMEGEAADLAGAASRYEALLRARFGVASAVAFDLMTLGIGDDAHTASLFPGTGAVGIADRLVAAIPAQPDKGLEARLTLTAPVIREARVKLLLARGASKRAVVEQAKRPGPADEVPARAVRGGAGRLVWLLDAAAAQAG
>NC_021658.1|WP_148313890.1|7541122_7542298_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA
MGPAGGRRPGPAVRGRARGVRRADAAGAGVEAAVSAGRIAEVIKRVESELAEFWSSPDESRPEPAPKTRASTMNFVAVGSRAEVERLKEQAEELAETHAGRTLLITLDDRLDPLSVQADWSATCRRAGEVPICYDRVELTFGVAAAERVASVVSALTISDVAVIVELAPGAPNVLGDALAPICDRLVFDSAETCIERIAEVARGTKAPLADRAFVRTFSFRELVARFFDDMPEASRAIRRVEIARSAGAKPDPAALLLGWMGSRLGWTFESRGPAQPGGAGVVGRARAADGAPIEIALVDGPPAGEQAQRRIDGVRLFTSLRGEPLALGCVRLDKAPATARWTMEGARSADHLHPLGYRDETWVLTKTIDSLEGDRLLREAVLAAAAWSAL
>NC_021658.1|WP_044988759.1|7542195_7543773_-|glucose-6-phosphate-dehydrogenase
MTQAEKNPLREGMPEERTASPAALVIFGASGDLTRRKLLPAVYNLALSRLLTGGFAVVGVARRPKPDFAQEMREAVGKYSRRPLEEASWSELEKGISYVQGSFDEPETYARLAAELERLDAERGTRKNRVFYLAVAPDQFAPIVRGLRAANLVAPPSHEKDAPFQHVVVEKPFGEDLESARALNRDLLAHLAESQIYRIDHYLGKETVQNLLVLRFGNTIFEPLWSRQHVDHVQITVAEEIGVEGRGKFYEKVGITRDIVQNHALQLLTLVAMEPPSSWDADAVRDEKVKVLRTLRPIEGPDALSSTVRGQYAAGIVRGEKVPGYTEEPDVAKDSMTETYVAMKLHLDSWRWGGVPFYLRAGKRLAKRVAEVVLHFKPLPHGLFKGAPGATEEPNALVMRLQPDEGISLRFAAKIPGSGIAIRGVTMDFRYGAAFGSSTPEAYERLLLDALRGDATLFTRADEVEAQWGFVDPIFEGWRTQNAPIARYAAGTWGPPEADALVQPSEGARGACGERTPPERAWRRP
>NC_021658.1|WP_020737183.1|7544262_7544607_+|DUF433-domain-containing-protein
MAAPVLPRIRVPHPHVRCDSQVLAGSPHVAGSRVPVRRLWAWHRGGASVETLLKRYPNLGPARVLDALAFAYDNQDLIEADIAREQALFEKKGGPTVGARPLAQLDLPFDEGDE
>NC_021658.1|WP_020737184.1|7544891_7546160_+|hypothetical-protein
MPLALLGLASPLLVNCGGKGIPGADSLPGPAGDLASAAGGCEELKNGGIANLKFEGGADVEGKIKGFLEAAASLDKLTADLEADLIASCGKLGKDLGMSEAELKAEPSGGKGAEKVCNAVSAKVNAAVKANAEAKLAVQIEPPKCYADIEAMQKCLGDCGSPVQPGKLEASCEGGEISGKCDAECKGKCTVDAGAACSGTCNASCSGKCEAGFKGTCGGKCDGKCDGKDSKGAACAGTCEGKCDAKAEGSCTGTCDGSCSGSCEIKGSAKCSGSCSGGCSAEIKEPKCSGEFKPPSVDPSCQMQCTAKTAGEAKCDAPNVRIVANGKVNADAQKLVAALRASLPAIAKVQLGTGKKLAAAVSGVGKAGVEVKDAALKAGGKAVACVAAAVDASASATASIDVNIKASASVSGSASGSASGGT
>NC_021658.1|WP_187345633.1|7546523_7550294_+|protein-kinase
MVGGPLIERGARIGEYTIDEPLGEGGFGTVFRGHDASGNVAAIKIFKEVSAQNVGQLFAQQNEIEALLRLRHPSLVKLSSYGVLDGIGLYLAMELVQGETLDRYLARMGSLDTIEALRIARRVAEALAHCHALNVLHLDLKPSNIVLTDPYEPRLKILDFGLATLTVSFQPEHARVNAGTIAYLAPECLKRGGLARPSPRMDLYAVGVVLYELLAGRLPFADGTVDSVINQKVYGTLVPLSTVAPETPAPVVALVDELMQRDPARRFSSAARLCARLKELYYVTLHGTSQPPAAEAAERERDAAPPEALDDAPFIGRELELGRLAELLQGAVCGEPRPAVVVGDTGVGKSRLVAELLRTVEQTGTAIVAYGRCRELSGLVPYSAIREALTQIALWLERHNDSRAARIRRLVSLVVADDAALLQGLVPELMRAVGLADAGGAIGPGGTRWIADLLLRLLGAIAEEIPVVLAIEDVHWADEATQDVLLRISDQLGERPILLLGTARPPFPGRGAPGSTLPPPASAGLRGAPGSSPMTPRSAGWLAWKGVERLDLGPLPPEANRALLSALGRGAGDDLVQELVRRVPLLAAGNPLFNIQVVRNMETEGFLQRGRGGALEISRADAHYRAPASVSDVLARSIEALDPTTVQVLGVAALIGRQFLRDDLVELGLFGPAAVDSALRDAAAHHICLSEDGGLTSFSHDAAREQLAARVPPEDRGEVHRRIARRIELRGGDPGTLAHHVERAGELDRAAETYLLAANEADRLQDPHGASRRLKQALALLERLPLDPARIELRARCAHELARVACLLGSTAEPLDLLRRTQGALPDTPLVTAALSSALSRVHYVRGEFADAVAHSRKALQAIGASPELRPYQCLPANILGRALCAAGKVGPATEPLRRGCELAEAAGEYIELCHSRGILCVALSQAGCYAEAEQSAADAARLAERLRDPVRLLGTWFYYAVLAEGRFDWDLGVRSTAQLLSYTEEHGLSGLYLYLGTMYAGRHQFHVGHLARARVLIANACNLSGVLGIGMGRGWAEGYLGDVLFVQGQHREALAAYDRAIEIGSAGTGDAYAVGLGRVGRVHARALLGGDAGELRAYGRETLELIRASGNRTQLVTALERCAEAFDALGDETEARDVRAEREVLVDELGLVEPTFWPRPPVEAAFQGPPRAYWTDAPREVRSSAPSSLGTTQFVGATVAELAAAATLAITEDDLGARTHVAIPRLRHVTLLETLASVEGFVPRFDGPEAPPVAK
>NC_021658.1|WP_148314880.1|7550389_7551097_+|1-acylglycerol-3-phosphate-O-acyltransferase
MLFLVVLLPVGLLCFPFDPRQRMHDRLSVVWAAGALWLVGVRVEAEGAEHVRPGERYVIAANHQSTLDILALLVVLQARAPFRFLAKRALFRVPVLGWGMRLYGHTPVDRGRARGAVADLGAAQRNLMRRWSTVFFPEGTRSATGRLLPFRPGAFRVAAAAGARVLPVTLVGAGALQPKGRYAAAPGVVRVVVHPPLDPPGPSLEELRASMDACRAAVGSALPEALRGAGEPGSG
>NC_021658.1|WP_187345634.1|7551797_7553660_+|protein-kinase
MKEGETLGGQYKLVQRLGKGGMGEVWEAADVLDGRRVALKFIACKTDELRRRLLNEARLCGALRHPNIVEIHEVGETDDKDPFLVMQLLTGETLADMLDRKKRIDPPALVARIGRDIAGALDAAHGAKIIHRDLKPANIFLHREPDAEERSFTVKVLDFGVSKSLNATGVQSTMTGLAVGSPAYMSPEQLSMSKRLDHRTDIWSLGIILYEMLTGMRPFRGATVNDVVHQVLFEPIRPVSHRLRSVPPALDELVARCLERDRNHRFPDATSLARALASIAEGTAVSRVILDMSPSPTPNPEQASMGPMPDAGPASPASPRRAPMDFGLGGGPPGFPRRPTMSSSPATAVTAWQESTLPLPPGTPASPGAAQAATEAAGAPRRAPRLAPTGTQLMSPSAPTASPLPAWRREAQPAAETRHPAVDTRSASLPELSPQDGALAHPPEEALGHGAATGQVPGVTTTTAPIARPAAEGAPASAPVSPRRGRDVGAWLYVAVGAGIISTIAALVIVVMLGASSDEPKPAEAPTPPASPGRAPPATATSAVLEAPPIPDAAPTTTASAAPTPPTEPPPSTTSQPATSGAATLRPPAGAVKPSIKQPLRQPCKRFIKTPGCYEPKAKP

Crispr_ID: NC_021658_27

• CRISPR_ID: NC_021658_27
• CRISPR_location: 7992019-7992095
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_27

Consensus_repeat	Method
CGGGCCGCGCGCGCCTTCCTGGA	CRISPRCasFinder

spacers of NC_021658_27

>27.1|7992042|31|NC_021658|CRISPRCasFinder
CCCGGAGCTCCAGGCCGGCAAGATCACGCCC

CRISPR arrays and Neighbor proteins around NC_021658_27

CRISPR arrays

The CRISPR arrays of NC_021658_27

>merge|NC_021658|27|7992019-7992095|CRISPRCasFinder
CGGGCCGCGCGCGCCTTCCTGGACCCGGAGCTCCAGGCCGGCAAGATCACGCCCGCGGCCGCGCGCGCCTTCCTGGA

>NC_021658|27|23|7992019-7992095|CRISPRCasFinder
CGGGCCGCGCGCGCCTTCCTGGA	CCCGGAGCTCCAGGCCGGCAAGATCACGCCC
GCGGCCGCGCGCGCCTTCCTGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020737497.1|7997317_7998142_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737487.1|7979505_7983456_+|M36-family-metallopeptidase	unknown	unknown	gnl|CDD|341059
NC_021658.1|WP_020737489.1|7984317_7986543_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_049949648.1|7994475_7995261_-|hypothetical-protein	unknown	unknown	gnl|CDD|310597
NC_021658.1|WP_020737484.1|7976271_7977084_+|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NC_021658.1|WP_049949647.1|7974063_7974954_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|335469
NC_021658.1|WP_020737499.1|7999556_8000078_-|DUF2243-domain-containing-protein	unknown	unknown	gnl|CDD|370775
NC_021658.1|WP_044986224.1|7975298_7976159_+|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|223740
NC_021658.1|WP_020737488.1|7983596_7984256_+|carbonic-anhydrase	unknown	unknown	gnl|CDD|239473
NC_021658.1|WP_044988829.1|7996730_7997219_+|Cys-tRNA(Pro)-deacylase	unknown	unknown	gnl|CDD|237976
NC_021658.1|WP_187345645.1|7995406_7996699_-|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl|CDD|270872
NC_021658.1|WP_044988823.1|7977170_7977812_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|182251
NC_021658.1|WP_020737490.1|7986771_7988793_-|hypothetical-protein	unknown	unknown	gnl|CDD|215193
NC_021658.1|WP_044988826.1|7992814_7993297_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314889.1|7977814_7978648_-|hypothetical-protein	unknown	unknown	gnl|CDD|223248
NC_021658.1|WP_020737494.1|7993486_7994413_+|hypothetical-protein	unknown	unknown	gnl|CDD|225256
NC_021658.1|WP_044986225.1|7989440_7990358_+|lytic-polysaccharide-monooxygenase	unknown	unknown	gnl|CDD|180777
NC_021658.1|WP_148313927.1|8000323_8001100_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_020737492.1|7992476_7992719_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949649.1|7998341_7999568_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020737487.1|7979505_7983456_+|M36-family-metallopeptidase	gnl|CDD|341059	cd09596, M36, Peptidase M36 family, also known as fungalysin family. The M36 peptidase family, also known as fungalysin (elastinolytic metalloproteinase) family, includes endopeptidases from pathogenic fungi. Fungalysin can hydrolyze extracellular matrix proteins such as elastin and keratin, with a preference for cleavage on the amino side of hydrophobic residues with bulky side-chains. This family is similar to the M4 (thermolysin) family due to the presence of the HEXXH motif in the active site residues, as well as its fold prediction. Some of these enzymes also contain a protease-associated (PA) domain insert. The eukaryotic M36 and bacterial M4 families of metalloproteases also share a conserved domain in their propeptides called FTP (fungalysin/thermolysin propeptide). Aspergillus fumigatus causes the pulmonary disease aspergillosis by invading the lungs of immuno-compromised animals; it secretes fungalysin that possibly breaks down proteinaceous structural barriers. A solid lesion known as an aspergilloma can grow in a lung cavity, particularly following recovery from tuberculosis. Fungalysins are also found as multiple copies in the human and animal pathogenic fungi such as Microsporum canis, Trichophyton rubrum and T. mentagrophytes, which cause cutaneous infections.	1.66708e-42
NC_021658.1|WP_020737489.1|7984317_7986543_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.21245e-95
NC_021658.1|WP_020737484.1|7976271_7977084_+|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	5.66816e-41
NC_021658.1|WP_049949647.1|7974063_7974954_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	0.0010352
NC_021658.1|WP_020737499.1|7999556_8000078_-|DUF2243-domain-containing-protein	gnl|CDD|370775	pfam10002, DUF2243, Predicted membrane protein (DUF2243). This domain, found in various hypothetical bacterial proteins, has no known function.	2.27394e-51
NC_021658.1|WP_044986224.1|7975298_7976159_+|mechanosensitive-ion-channel-family-protein	gnl|CDD|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	9.56431e-43
NC_021658.1|WP_020737488.1|7983596_7984256_+|carbonic-anhydrase	gnl|CDD|239473	cd03378, beta_CA_cladeC, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	6.50513e-58
NC_021658.1|WP_044988829.1|7996730_7997219_+|Cys-tRNA(Pro)-deacylase	gnl|CDD|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	1.30064e-67
NC_021658.1|WP_187345645.1|7995406_7996699_-|AarF/ABC1/UbiB-kinase-family-protein	gnl|CDD|270872	cd13970, ABC1_ADCK3, Activator of bc1 complex (ABC1) kinases, also called aarF domain containing kinase 3. This subfamily is composed of the atypical yeast protein kinase Abc1p, its human homolog ADCK3 (also called CABC1), and similar proteins. Abc1p (also called Coq8p) is required for the biosynthesis of Coenzyme Q (ubiquinone or Q), which is an essential lipid component in respiratory electron and proton transport. It is necessary for the formation of a multi-subunit Q-biosynthetic complex and may also function in the regulation of Q synthesis. Human ADCK3 is able to rescue defects in Q synthesis and the phosphorylation state of Coq proteins in yeast Abc1 (or Coq8) mutants. Mutations in ADCK3 cause progressive cerebellar ataxia and atrophy due to Q10 deficiency. In algae and higher plants, ABC1 kinases have proliferated to more than 15 subfamilies, most of which are located in plastids or mitochondria. Subfamily 13 (ABC1K13) of plant ABC1 kinases belongs in this subfamily with yeast Abc1p and human ADCK3. ABC1 kinases are not related to the ATP-binding cassette (ABC) membrane transporter family.	1.22116e-79
NC_021658.1|WP_044988823.1|7977170_7977812_+|HD-domain-containing-protein	gnl|CDD|182251	PRK10119, PRK10119, putative hydrolase; Provisional.	4.16373e-71
NC_021658.1|WP_020737490.1|7986771_7988793_-|hypothetical-protein	gnl|CDD|215193	PLN02337, PLN02337, lipoxygenase.	2.25645e-51
NC_021658.1|WP_049949648.1|7994475_7995261_-|hypothetical-protein	gnl|CDD|310597	pfam06112, Herpes_capsid, Gammaherpesvirus capsid protein. This family consists of several Gammaherpesvirus capsid proteins. The exact function of this family is unknown.	0.00446177
NC_021658.1|WP_148314889.1|7977814_7978648_-|hypothetical-protein	gnl|CDD|223248	COG0170, SEC59, Dolichol kinase [Lipid metabolism].	9.75695e-16
NC_021658.1|WP_020737494.1|7993486_7994413_+|hypothetical-protein	gnl|CDD|225256	COG2382, Fes, Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism].	2.108e-12
NC_021658.1|WP_044986225.1|7989440_7990358_+|lytic-polysaccharide-monooxygenase	gnl|CDD|180777	PRK06958, PRK06958, single-stranded DNA-binding protein; Provisional.	0.000165716
NC_021658.1|WP_148313927.1|8000323_8001100_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	2.42972e-06
NC_021658.1|WP_049949649.1|7998341_7999568_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.17926e-90

Protein sequences

>NC_021658.1|WP_044986225.1|7989440_7990358_+|lytic-polysaccharide-monooxygenase
MRLKAPWRAPAAATLAAAALAAIDPAVAHAHFALLEPACYSEQSDLGDPQKSAPCGQADPGNPIEPTGEVTTYVQGQTIQLRIDETIFHPGHYRVSIAENPESLPPDPEVAPGATPCGSTVIEADPQLPLVADGLLVHTSAFTGEQTVEIKLPDDLTCENCTLQVSEFMSNHGINNPGGCFYHHCATVTILPREGEPTGAGGTGGAGGESGEGGAASSSVSSGGSGDGGSAASSGGSAGDGGAGASGDGGSAGADASDASSSGCGCRVGAAEDPTIATVAGLIALGLLRWRRRAVAARAGWRSTL
>NC_021658.1|WP_020737490.1|7986771_7988793_-|hypothetical-protein
MSNPSLPQNDSPAEQQQRKSELARAQQTYVYDHDTRLSPLGVAQSVPNGQGFAPILVGSAALVILDLVGNVVAKASKLVGSDGSLRSPKGAPLDDATSARIQGVLHDLKQRHRELTLVLTPLHGEPERAPAPPPRAPAVALVEGVAQKFVTTAENRAMESVLGATNLSTKNVGDIIKSLLDTLLSAAGKLLLDLVGMYGQATSVYDYVSEFQTFRLPEIASVYQDDAIFAWMRVAGPNPLVLKRVASPGASFPVTDAQYRSVMGEGDSLASAGKEGRLYLADYKALSQLVPGTAPDQQKYVEAPLALFAVPAAGAPSRLLRPVAIQCAQAPGAASPIFTPSDGVAWEVAKLHVQVADGNFHELISHLGQTHLVLEAFAMATPRQLAPEHPVNVLLTPHFQGTLAINNAAEADLIAPGGPVDNLLAGTIASSTQLAVDAVLSYSVNQQFLPVALAQRGVDDPSTLPSYPYRDDATLLWGAIHTWVSRYLAVYYTSDADVLGDYELQHWIAELSSPSGCGLKDIGEDGAIRTVAYLADLLTHVIFTASAQHAAVNFPQSSLMSFTPALPLAAYAPAPSITAGLPPSEIFQHLPPLQQALLQINVMMLLGGVYYSRLGDYDRNIPGAYFTDARVREPLEAFQRELMEIEATIGKRNLQRFPYVVLLPSQIPQSINI
>NC_021658.1|WP_020737489.1|7984317_7986543_-|protein-kinase
MDASIPGVPAPGEILADKYRVERVLGRGGMGVVLAAEHLALRQPVALKLLLPSCMQSASAVERFLREARAAASLQGSHVVRVLDAGLLDAGTPYLVMERLTGHDLREVLRQRDHLPIDEAVDLVLQACEAIAEAHARGIVHRDLKPANLFLARDERGVALIKVLDFGLSKCAADDEAYSLTSPNLIAGSIPYMAPEQALGLKWADARADIWALGVVLYELITGRRPFEAGRTPESLLASHDAPPAAVSAWGIDAPAGLESAILRCLEKDRHLRPQTIAELAQAIAPFGTPAARASVERIRRCSPPRDLCEPSLEPTEPLSPARAGRARPGDEGATALLPHASAAQRTASDAPPRAHRSVSPVVTSAAGAGAPGPRLTADASAFAPARPRRGSSALLAFAVAAAAALAWALSRMAPPEPTPAEIAPERLESFAPLPTGPTQPLDPTAAAQIRLGRMLFQDPRLSGHHDVACTSCHPLDTWGVDRRKLSRGSEGREPPRNTLSIYNIAGYFAFLWDGRQGNLVEQAKEVLLSRNAMASTPEGIEAALRSSEGYARAFALAFPEQRDAVTFHNVAQALAAFEATLFTRSRWDAFLEGEKTALSGEEKAGFNAFVDTGCISCHFGPDIGATMYQKAGLVKPWPNTKDRGRYEITRRGADWMVFRVPSLRNVAQTGPYFHDGSVSSLEEAVRMMARHQLGKELRDREVYLIVRWLGSLTGEIPRADIELDEASRAIVTNATSRAAP
>NC_021658.1|WP_020737488.1|7983596_7984256_+|carbonic-anhydrase
MGITNNPPASPVLSAGQALERLAEGNRRFVDDACGEHVVLGQRARAALVDGQRPFAIILSCSDSRVPSELIFNQGLGDLFVIRVAGNVVAPSLVGSVEFAAAAFGTRLAVVMGHSRCGAIDATLSELLQDESRGDLTDNIRDIVERCRAPVQTVVSVAGRHAPRDLLMREAVRANVRNSCDHLRHGSRLLERLCAEEGMQIVGAEYALETGKVTFLDGA
>NC_021658.1|WP_020737487.1|7979505_7983456_+|M36-family-metallopeptidase
MKVSVRYTALSFALLAGPLAHARERPNHDAYFREPPALPPGVARVAGDDAPGAVVASTDPQRGVPTFVWATSPEQRPPAATHSTAESAARWYVQRYARLYHLPQAALDTAVVRHVHDTGRGGILVTLGQDVDGIPVFRSELKVLMKRDLTLVALGGNLHASAVALPPGAGSLRPGSKRSRAFAGAPAQAVVRAVRDAHRIDIKTADLRDLGEAKGGYGLFDLADTAHARQRAGSLRFAQPARVRKVLFPLPDRLVPGYFVELVSGDAERTSSDATAWVFGASDGRYLYRENLSHAATFDYRVWTEDDDKHTPLGGPLADMSPHPTGRPDGHLPRFIAPSLISIEGFNTNPDGRADPWLPADATSTRGNNVDAYADHNAPDGFSSGDTRAELSGPGAFDYTYDLRAEPLAAPEQIMAAVTQVFYVTNWLHDWYYDSGFTEAAGNAQRDNLGRGGLDGDPFLAEAQDDATGGSRDNANMDATYDGASPRMQMYLWTGPDLRSLSVTPQNANYASNTAMFGPQRYEVTGELALGEDDAAPRGDACGPITSDVAGKVALVDRGGCAFAEKARNAQEAGAVGVIIANNRESDGAPRLAGDDPDVTTPAQSVSLEDGGALKAALAGAQAPLRITMTREPSVERDGTIDNTIVAHEWGHYIHLRLVACGTQMCGAQSEGWGDFIALHMALREGDDLDGAYPLSSYGSAALGDSYFGIRRAPYSVDFAKNGLTFRHIADDERLPDHPLNVSAPQNSEVHNAGEVWAAMMFEAYVALIQHGSGLTPPRAFEQTRRRMSDYVVAGMKLAPANPTYTEQRDAVLAAALASDQGDFRAMAEAFARRGAGTCAVSPRVDAQGLSGVVESFKVQPEIALVRAELDDSAGSCDRDGLLDAEESGTVTIEIVNRGAAPLSGAVASIEGPGGGVTFPDGARVSFGDIAPFATGTATVPVKLDRNMKPAEDLKLDLTLKSAEACTPTRVEALVRRVNYDEVPGSSAVDGVETQSTTWTVEGLSGELVWSRAEGTAPNRVWRGVDLGTLSDAALVSPPLEVSETERFVLTFAHRHQFEASDGTFWDGAVIEISADGGETWVDVAKTADPGYGGRVTSESGNPLARRRAFVGESPSWPELDRVSVDLGTAFAGKTVRVRFRVGTDEAAGDTGWELDDIGFAGVKNKPFATLIEDTASCQRGPAADAGADQAVAVGELVTLDASGSSDPEEDELTFSWTQTAGPAVELLGDGARATFVAPEVAAATTLAFEVKVSDGILEAADQVSVVVDPAREPAPPEEGCGCAIPGGAPRAPLGALGAAAAVAALAARRRRGAGR
>NC_021658.1|WP_148314889.1|7977814_7978648_-|hypothetical-protein
MVLRLRELVVAAERDDAGGALDRLRDRLRALLAAVERATPSGTPSPKAAWIAFQREVQPAYESLLLTLRGVVAAPPSVRPTNHARSLWHVGSGLAVLGLVQLLPERGSLVAVSGAFAAAAWSMEIARRVSERVNDRLMRVFRLVAHPHERYRVNSSTWYMTALLLLALFGSRLSQSLAVVVLAVADPAAALIGRRFGRTRLRDGRSLEGTLAFFAAGALSSLAVMWALGPASLSSRLLLAAVAGLAGAATELFSSRMDDNFTIPVAVAAAVTVAGAG
>NC_021658.1|WP_044988823.1|7977170_7977812_+|HD-domain-containing-protein
MRDWEALFAKKLEQTDLGKDPAHDLAHFTRVVATAKALAADEGARLEVVVPAAWLHDLVNVPKNDPRRSQASRLSADEALRFLRSVAYPEAFLADIAHAIEAHSYSAGIEPRTLEARVVQDADRLDGLGAIGIARCFAVGGLLGVRFYDPQDPFAERRPWNDRENAIDHFHVKLFKTAESLRTAAGRREGARRAEFMRQYLAHLAVEIGAEVP
>NC_021658.1|WP_020737484.1|7976271_7977084_+|mechanosensitive-ion-channel-family-protein
MNIEELTPSLATLRAIATAIVILVAGWLASKWAYRIAVKTLSSSHLDQALARFLASMLRYVVLAATFIASMETVGIHTTSLVAVVASAGLAVGLALQGSLSNFASGVLILFFKHFQLGDKIAIGDHRGIVEDIGLFTTTLVSTDNEKIVIPNASVTNGPIVNFSDRGLLRGAVTVNVEGRLRDLGPAMAAMVRAAKRAGGVAQEPAPTVFLTDMEDGSLDLTLTAWYRAVDEDESMHNLRVAVLEELDAAGIKLMNRTQLILHQRSKMPS
>NC_021658.1|WP_044986224.1|7975298_7976159_+|mechanosensitive-ion-channel-family-protein
MDERVQRYMDMGVALGVSVGTKIVGAILVWVIGRMIIRGVLSVMQRSSALKKLDVTLAHYLESAVSVLLNILLIIAVLSVFGVETTTFASLLAAVGIAIGMAWSGLLSNLAAGVFMILLRPFKTGDVVTAGGVTGAVHSIGLFATALDTGDNVRTIVGNAKIFSDTIQNFSANPFRRVDCTAQLAHGADHEVAIARLKARLPLIPNVVSEPAPVVEILEFNLSGPVLAVRPFCHSGSYGDVFFATNRVIREELGKLGLPVPSQHVQINQLAAAAPRGAGAEAHPTA
>NC_021658.1|WP_049949647.1|7974063_7974954_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MSEPPQSELPPSEPPQSEPPLVASPEIETDGPLDEPTTDEIPAIEAPVTLPGRTEGCPGGMVRVEGEYCPAVVQECLEYHPEWTKRHGEPGVAARCLRFREPSRCVAKKNESLSFCMDRYEYPNVPGELPRTLTSWEQAADLCEAQGKRLCTEAEFNFACEGPEALPYVYGYERNAETCNQDREYRFPDHSQRLLHHEACMQNERCAAELARLDGREPAGSRAECASWAGVFDLNGNVNEWVVRTDQKAPYRSGLKGGWWGPIRSQCRPMTTFHKEDDYGYEVGFRCCADVEPQAT
>NC_021658.1|WP_020737492.1|7992476_7992719_+|hypothetical-protein
MEASEKAAVKRQPEAPEGAAAGPEPTEEEARGERIPETPVDRGGALSPREPEAPVEPEDEASDESFPASDPPAWTPGHSG
>NC_021658.1|WP_044988826.1|7992814_7993297_-|hypothetical-protein
MGQARPVRPEDQDPKLWRGQGWTARVIKNEDDDGWAVEMTCDGQSEPSLVGPWTMGRDKKNPKPLDASAFATLVKTANEVLARHVQQRRAQLHRNVTVAVEGGARVRVDLDVVPDEDDPHAILTVHDAAGEVVSRSRVPADFKLTTESARRWLEGGVPEA
>NC_021658.1|WP_020737494.1|7993486_7994413_+|hypothetical-protein
MLLPRRPFLALCAAALAPRAALADPAGAPSAAPPPPSPSAPPAFDVRDLQVPGDRALGRRFTLVVPRHLAPGERAPLLVLLHGLGETGDERLGAFAWLERYGLGSSYERLRRPPLGRTTRRKDWTDARLAEVNAALAARPFRGLAIACPYTPNVHKAPNPSAALDGYARWLAEVVLPRARAEAPVFDDAARTSLDGCSLGGFVGIEVFLRRPELFGAWGGVQSAISAHRAPAYADRLARAVAATGPRDLHLLTSKGDPFHDANAALAAQLAKRSIPHALRVLPGPHDQPWLREAGTVEMLLFHDRRPR
>NC_021658.1|WP_049949648.1|7994475_7995261_-|hypothetical-protein
MNRLAHRRTIAALALLAAACGGSSDDAPDDGSGGTTVSGAGGGTTASGAGGGTTASGAGGGTTASSGTTAPEGEILALEIVEWHQDESALRVSLILRNQDTLPLPVTPESFSVASTDGFSLGWVPFRWITNPCPAVNLPSSGSLRCEMGFSKSAEQEPARLVFAALDGRQIETPFPAESPITADNICSHFSFEGRCYECATECGLYDSVCTSEEDWINLDRLLFSAGAACTEGAPLLSEACFDGLLTCIRDGCVEDCGFHP
>NC_021658.1|WP_187345645.1|7995406_7996699_-|AarF/ABC1/UbiB-kinase-family-protein
MTTEKKLPEGRLNRFVRLAGLGARAGATHLFARRGDAAADAAAHVAEVLGTMRGLAAKVGQMASYVDGFIPEPQREAYEAALRSLRAAAPASSPAAVRAVVEEDLGARVDELFAAWDDAPFASASIGQVHRAALADGREVAVKVQHPGIDRALASDLENAGMIRAMVGAVAPKALDSRRVLEEVRARFLEELDYTLEAERQRYFAGVHRGDPAIHIPEVIASRSSRRVLTAELARGATLEEAAARDERTRRAHAEALWRFVFKGNLVGGMFNADPHPGNYLFHADGRVTFLDFGCVERLDGARLEHGRGMHLAALRKDEAAFARHAALILGTRGGRFEELSLAYTRRCFEPLFSAPFRVTRAYVTSLVEGVMAIKQQILVKDSGFVQLPPGMVFLNRLQFGFYSVLARLDVEVDYAAVERAFLREAGLLE
>NC_021658.1|WP_044988829.1|7996730_7997219_+|Cys-tRNA(Pro)-deacylase
MKTNAARILDSLGIPYELRTYEVDPSDLTASTVARKIGLPPEQVWKTLVARGDRHGVCFAVVPGNAQLDLKAIARLTGDRKVDTVPLKEVQPLTGYVRGGVTALGAKKAYPVYADETIELFDVVSISAGVRGTQILVAPGDYLRATKAAVGPIVAAPGGDAD
>NC_021658.1|WP_020737497.1|7997317_7998142_+|hypothetical-protein
MTRAACDVRDPSELTTAELRQLCQGSHPWELGLGAVQLVASAAAGGAVLAAAAACIPGLVQCISVGPAFAAGLAVWESLGAARSWLPGAAYREELAFRAWHAGLFPWAQPHALRRWARRAMARRPAPDWLLVLEGIAPAGGGRRWVKVELSLSPSSDGPFRSQASGHALLHPGGGGAAEPRERRLAPEELDDLGRALAELPDGLSLAPLAWPRSPAAFSGHCELLIARRAPFAVVQLTCAFPSREAGAQPPSLSLLHRLAQMAWGEGGPARAER
>NC_021658.1|WP_049949649.1|7998341_7999568_+|serine/threonine-protein-kinase
MIGQTIDRKYKLVRLLGQGGMGSVYEAEHTTTQLRVAIKVLSTRHLLPGSEGVKRLRREARAASAIDSEHIVQVLDAGTDEETDTSYIAMERLHGKDLQQRIDAVGPLPPDVVLRIGAQALAGLQKAHEARIVHRDIKPANLFLARRPDGSLTVKILDFGIAKILADPLAVAHTTGLTHTGSVLGSPLYMSPEQVQNGRDVDHRTDLWSLASALYCALAGHAPYQQVGTLGKLVYTICSTPPLPLHEIAPWVPVEVAAVIHGALALDPSARYPSAAAMLAAMRPLLTGGTALDPSMMRAERGASEPASSAPSLALACPGGELLGSSVEASAPAPGGETTASLDMTSAAEGEAGAAVAQGDPMTTLAVPLPLTAAVPVTEARDVSRDAADRAGDPARRRPSPRRAPSSR
>NC_021658.1|WP_020737499.1|7999556_8000078_-|DUF2243-domain-containing-protein
MSTARPLDLDTPTRTLRAVKTAGLLFGLGAGGLIDGILFHQLLQWHHLICFSCHPGATIDDVRRNIFADGLFSAVAFGLTVAGVSKLWCALRSGGALLPGRILPGAAAVGWGLFNLVEGVIDHHLLQIHHVRPGPGQLGWDLAFLASGGLLVLGGLRLMRAAPRGARAGLSAG
>NC_021658.1|WP_148313927.1|8000323_8001100_+|hypothetical-protein
MNPERAAGTPEPEHQGPKPVPYTYHDGREDYLHVGRQGGTEADQPTALVPPSEGMSPRVETTALPPEASALPPATTVPAEAASPPARASALPPEATALPPEAPRAAAQRPQQGARMSEIVTRGLRTGAALTAATMCTMMAASTLKRGSPWASMNAMATAVGLGGRRASDRFDPVVTPAGVAVLAGGLLAWGIGYEKALDATGKRSSPLTGALSALGGFLFDELILPDRLMKNFRDKMGVLGTLSKYVALGVASAAAPR

Crispr_ID: NC_021658_28

• CRISPR_ID: NC_021658_28
• CRISPR_location: 8011479-8011543
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_28

Consensus_repeat	Method
GCTGAGCGCTCCCGGCCGGCGGCGC	CRISPRCasFinder

spacers of NC_021658_28

>28.1|8011504|15|NC_021658|CRISPRCasFinder
CGGGCTCGGCCGCTG

CRISPR arrays and Neighbor proteins around NC_021658_28

CRISPR arrays

The CRISPR arrays of NC_021658_28

>merge|NC_021658|28|8011479-8011543|CRISPRCasFinder
GCTGAGCGCTCCCGGCCGGCGGCGCCGGGCTCGGCCGCTGGCTGAGCGCTCCGGCGGCGCGCGGG

>NC_021658|28|24|8011479-8011543|CRISPRCasFinder
GCTGAGCGCTCCCGGCCGGCGGCGC	CGGGCTCGGCCGCTG
GCTGAGCGCTCCGGCGGCGCGCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_187345646.1|8016557_8016728_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737497.1|7997317_7998142_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187345647.1|8024163_8024880_+|energy-transducer-TonB	unknown	unknown	gnl|CDD|223880
NC_021658.1|WP_063752029.1|8013939_8015640_-|DUF1592-domain-containing-protein	unknown	unknown	gnl|CDD|377886
NC_021658.1|WP_044988829.1|7996730_7997219_+|Cys-tRNA(Pro)-deacylase	unknown	unknown	gnl|CDD|237976
NC_021658.1|WP_044988833.1|8001745_8002534_-|glucose-1-dehydrogenase	unknown	unknown	gnl|CDD|180440
NC_021658.1|WP_148313929.1|8012598_8013930_-|DUF1552-domain-containing-protein	unknown	unknown	gnl|CDD|377875
NC_021658.1|WP_148313930.1|8025699_8026476_+|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	unknown
NC_021658.1|WP_020737505.1|8006157_8010033_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_080682328.1|8022803_8023247_+|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|379650
NC_021658.1|WP_020737499.1|7999556_8000078_-|DUF2243-domain-containing-protein	unknown	unknown	gnl|CDD|370775
NC_021658.1|WP_020737508.1|8011769_8012450_+|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NC_021658.1|WP_044988832.1|8001151_8001616_-|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NC_021658.1|WP_020737515.1|8023382_8023958_+|energy-transducer-TonB	unknown	unknown	gnl|CDD|273570
NC_021658.1|WP_049949649.1|7998341_7999568_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020737503.1|8003208_8004153_+|hypothetical-protein	unknown	unknown	gnl|CDD|224117
NC_021658.1|WP_080682756.1|8020743_8022807_+|hypothetical-protein	unknown	unknown	gnl|CDD|274730
NC_021658.1|WP_148313927.1|8000323_8001100_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_049949651.1|8026777_8027773_+|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NC_021658.1|WP_020737504.1|8004374_8006105_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_187345647.1|8024163_8024880_+|energy-transducer-TonB	gnl|CDD|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	0.00298848
NC_021658.1|WP_063752029.1|8013939_8015640_-|DUF1592-domain-containing-protein	gnl|CDD|377886	pfam07631, PSD4, Protein of unknown function (DUF1592). A region of similarity shared by several Rhodopirellula baltica cytochrome-like proteins that are predicted to be secreted. These proteins also match pfam07627, pfam07626, and pfam07624.	8.61508e-44
NC_021658.1|WP_044988829.1|7996730_7997219_+|Cys-tRNA(Pro)-deacylase	gnl|CDD|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	1.30064e-67
NC_021658.1|WP_148313929.1|8012598_8013930_-|DUF1552-domain-containing-protein	gnl|CDD|377875	pfam07586, HXXSHH, Protein of unknown function (DUF1552). A family of proteins identified in Rhodopirellula baltica.	1.10355e-65
NC_021658.1|WP_148313927.1|8000323_8001100_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	2.42972e-06
NC_021658.1|WP_020737505.1|8006157_8010033_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.33122e-78
NC_021658.1|WP_080682328.1|8022803_8023247_+|SMI1/KNR4-family-protein	gnl|CDD|379650	pfam14568, SUKH_6, SMI1-KNR4 cell-wall. Members of this family are related to the SMI1/KNR4-like or SUKH superfamily of proteins.	3.68112e-20
NC_021658.1|WP_020737499.1|7999556_8000078_-|DUF2243-domain-containing-protein	gnl|CDD|370775	pfam10002, DUF2243, Predicted membrane protein (DUF2243). This domain, found in various hypothetical bacterial proteins, has no known function.	2.27394e-51
NC_021658.1|WP_020737508.1|8011769_8012450_+|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	1.32105e-26
NC_021658.1|WP_044988832.1|8001151_8001616_-|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.000445665
NC_021658.1|WP_020737515.1|8023382_8023958_+|energy-transducer-TonB	gnl|CDD|273570	TIGR01352, Protein_TonB, TonB family C-terminal domain. This model represents the C-terminal of TonB and is homologs. TonB is an energy-transducer for TonB-dependent receptors of Gram-negative bacteria. Most members are designated as TonB or TonB-related proteins, but a few represent the paralogous TolA protein. Several bacteria have up to four TonB paralogs. In nearly every case, a proline-rich repetive region is found N-terminal to this domain; these low-complexity regions are highly divergent and cannot readily be aligned. The region is suggested to help span the periplasm. [Transport and binding proteins, Cations and iron carrying compounds].	6.7073e-05
NC_021658.1|WP_049949649.1|7998341_7999568_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.17926e-90
NC_021658.1|WP_020737503.1|8003208_8004153_+|hypothetical-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0.000197442
NC_021658.1|WP_080682756.1|8020743_8022807_+|hypothetical-protein	gnl|CDD|274730	TIGR03696, tRNA_nuclease_WapA, RHS repeat-associated core domain. This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.	2.0917e-19
NC_021658.1|WP_044988833.1|8001745_8002534_-|glucose-1-dehydrogenase	gnl|CDD|180440	PRK06172, PRK06172, SDR family oxidoreductase.	7.35895e-83
NC_021658.1|WP_049949651.1|8026777_8027773_+|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	0.00602408

Protein sequences

>NC_021658.1|WP_020737505.1|8006157_8010033_-|protein-kinase
MRVGDVIDRRFRLERLASSGGMGDVYRAIDLAANEPVALKVLQRRGLQEAIRFAREAEALEALTALRHPGIVRYVAHGATDTGQPYLAMEWLSGETLTERLARRSLSVRETLALASRVASTLGVVHRAGIVHRDLKPSNLLLVGGAVEGVTLIDFGVVRFGAIDRHLTMPGTMLGTPGYMAPEQARSEPNIDARADVFSLGCVLFKCLTGRSAFQGTDGLSVLIKVILEDPPRLRELRGDIPEALDDLVARMLAKPPNERPRDGDAVAAELLELDDLGAGAVSSRPSNTLRGSEITTNERKMMCLVLARDVTGDAEETRSQEEDLERSKALIAVAERYQGELEILESRSPLIVLSAGGAPTDLAAQAARCALALNALLGCVPVALVTGRAEISSRLPVGELIDRAVHLLPPAHAPAGADAVRMDEVTAGLLGSRFDITRDKGALRLHGEREALATTPPLLGRPTPCVGRDRELALLEAAFAHCVDESTPSAVLVTAPAGAGKSRLRTELLRRLRDRGEEMEVWIGRGDPMGAGSAFALLASALRRAIGLFDGEPIEARQHKIRARVARYGRGESPRTAAFLGELMGVPFPDGDSVQLMAARRNPVLMSDQIRLAWEELLRAECSARPVLLVLEDLHWGDLPSVMLVDSALRNLGDQRLMVLALGRPEVRELFPKLWAGRGVHEVQLSGLPRRASERLVRQVLGEDVAPELLTMIVDRADGNAFYLEEQLRAVADGKGADLPETVLAMVQARIEALDIEARRVLRAASIFGQTFWQGGVSALVGGAPVAPKLVELEQREVIARRGEGSLPGEVEYSFQHAIVREAAYGMLTEGDRRLGHRLAGEWLSRAGAADAMALGEHFERGGELSRAAAAYCRAAEQALRAQDLAAAVERAERGVACGPTAPTLGALRLVEAEAHVWRGELALAEQRGVEAVDRLPAGSAPWFSAIKQVAVAAGKLGGFERVERWMGVAQAAEAEAEGALVEKHMCLGEGALLLVFGGRYAFADALIEAVEGDGTDLAEREVEVEARLHEVRSIRALVNGDPGACLRGLSSALAAFERAGDRGNACAVRMNVGYMHAELGDFAGAEEVLRSALAAAERMGLHELAAATLSNLGHVLGYRGRIEEAQRTAREAIALSQRLGDPRQEGSARTYLARIALLARDYEAAEREARTAAEILQSAPPLRAAAVAARARALLGLGRYDEGLSAAGEAFSMLEGIGAIEEGESAVRLVYAEALEANGMEADCAAVIAAARERLLERAGKISDPVWRERFLTVPDNQKTLAMAERWVG
>NC_021658.1|WP_020737504.1|8004374_8006105_-|hypothetical-protein
MTNALAKSTRPRHLVAKLLEQPDLVRLVQGLEAPVLTRLIHHIGLEDAGEIVALATTEQLKGIFDEDLWRSERPGKDEAFDADRFALWLEVMLEAGEAFAARKIAELDEDFVTMALCKHVLVIDIEGLAMQMSSSERSDDDDLVDKALESCLYQEFEEFRIIAKDHRSWDPILQVLVELDREHHALLRALLERCCAISTEIIEESGGLYDVLTSEEMLESDVAAEREDRREQEGFVAPSAAVSFLNLARVTPLDEILGSRTYDAVTRAHFRAAAAKARPPAAAARRPDSGVEKGAPAAEDLQSFLEVLREADIVPPAAEARLLTAGAPREGEDLLFTSAIREVMARDAELYGKRLLELSYLVNVLISGCSHDGRAFRPFEAAEAVLCTCSLGLERLLGERAGRKKPGADELASAMTEHDAVKMFMAGWHLLHHEVVLFAAGALRKALAGLVAGQPDAQAAREIERVAAGLAADADAGKPWRSRGKLDRIERALGAEPTATYRALLDELPTLPDGAVEGARGAQRSRFVSSAAQIRALQAMLARPEGSGATAAPRAAGAAAPAKARKRAQPGAGRRK
>NC_021658.1|WP_020737503.1|8003208_8004153_+|hypothetical-protein
MNRPRLVAGALFLAGHLFALGCSAPKPEPEIASSAHQSGYAERYPAELQATATSFSEREDLAKRATGQFQGYPGELKKPDWKVAVEVIEQADAAGKSYDYVERLRVVNGAMEFFNENQEELTRKVSGAAQYVVKQKGCDADVTGATAHALEEGVARQLEEYVRDRNEAHRTIERHRASLGKENAATLERQADAVSFASYTVHIDMVEHKLRLRRMLEEIEAIKASIDEAVAAERAFQASGRRTDEEKKASDERIEELGRSKAMLDSSATQVKEIDATMEERIAAAQKGYREALDRLIATLRKNGGLPEAPPREG
>NC_021658.1|WP_044988833.1|8001745_8002534_-|glucose-1-dehydrogenase
MGALKDKVVIVTGASAGIGRETAVALAAEGAKVVASARREAQGRDLVAAVKDRGGEITWVTADMRVERDIEALVDAAVSTYGRLDGSFNNAGVGFLAPFVEMSNEAYDQFLDTNLRGAFWCMKYQIKAMLAGGGGSIVNCASVAASRSFPGLSAYAASKAGLVALSRGAAVEVAQKGIRINTVSPGIIESEMATAGWRLDDPQGRAFASSLHAMNRVGKPGEVAAAVAFLLSDKASFVTGQDIIVDGGLVPAAWPAGYAGGG
>NC_021658.1|WP_044988832.1|8001151_8001616_-|hypothetical-protein
MSGRGRRAPAPRVHAAGRSARVRGMHGARRWRGTMGRDRDNEERPEPQAQGKGRVDEVDQSKGIFRLDGPHPKDAELRAPGTLGGGPYEESGRGGPAGSLEPRDPSPASAGAAATPEEPSAQGDDAADEARPVAGALPQHEERSAEERRAAGQG
>NC_021658.1|WP_148313927.1|8000323_8001100_+|hypothetical-protein
MNPERAAGTPEPEHQGPKPVPYTYHDGREDYLHVGRQGGTEADQPTALVPPSEGMSPRVETTALPPEASALPPATTVPAEAASPPARASALPPEATALPPEAPRAAAQRPQQGARMSEIVTRGLRTGAALTAATMCTMMAASTLKRGSPWASMNAMATAVGLGGRRASDRFDPVVTPAGVAVLAGGLLAWGIGYEKALDATGKRSSPLTGALSALGGFLFDELILPDRLMKNFRDKMGVLGTLSKYVALGVASAAAPR
>NC_021658.1|WP_020737499.1|7999556_8000078_-|DUF2243-domain-containing-protein
MSTARPLDLDTPTRTLRAVKTAGLLFGLGAGGLIDGILFHQLLQWHHLICFSCHPGATIDDVRRNIFADGLFSAVAFGLTVAGVSKLWCALRSGGALLPGRILPGAAAVGWGLFNLVEGVIDHHLLQIHHVRPGPGQLGWDLAFLASGGLLVLGGLRLMRAAPRGARAGLSAG
>NC_021658.1|WP_049949649.1|7998341_7999568_+|serine/threonine-protein-kinase
MIGQTIDRKYKLVRLLGQGGMGSVYEAEHTTTQLRVAIKVLSTRHLLPGSEGVKRLRREARAASAIDSEHIVQVLDAGTDEETDTSYIAMERLHGKDLQQRIDAVGPLPPDVVLRIGAQALAGLQKAHEARIVHRDIKPANLFLARRPDGSLTVKILDFGIAKILADPLAVAHTTGLTHTGSVLGSPLYMSPEQVQNGRDVDHRTDLWSLASALYCALAGHAPYQQVGTLGKLVYTICSTPPLPLHEIAPWVPVEVAAVIHGALALDPSARYPSAAAMLAAMRPLLTGGTALDPSMMRAERGASEPASSAPSLALACPGGELLGSSVEASAPAPGGETTASLDMTSAAEGEAGAAVAQGDPMTTLAVPLPLTAAVPVTEARDVSRDAADRAGDPARRRPSPRRAPSSR
>NC_021658.1|WP_020737497.1|7997317_7998142_+|hypothetical-protein
MTRAACDVRDPSELTTAELRQLCQGSHPWELGLGAVQLVASAAAGGAVLAAAAACIPGLVQCISVGPAFAAGLAVWESLGAARSWLPGAAYREELAFRAWHAGLFPWAQPHALRRWARRAMARRPAPDWLLVLEGIAPAGGGRRWVKVELSLSPSSDGPFRSQASGHALLHPGGGGAAEPRERRLAPEELDDLGRALAELPDGLSLAPLAWPRSPAAFSGHCELLIARRAPFAVVQLTCAFPSREAGAQPPSLSLLHRLAQMAWGEGGPARAER
>NC_021658.1|WP_044988829.1|7996730_7997219_+|Cys-tRNA(Pro)-deacylase
MKTNAARILDSLGIPYELRTYEVDPSDLTASTVARKIGLPPEQVWKTLVARGDRHGVCFAVVPGNAQLDLKAIARLTGDRKVDTVPLKEVQPLTGYVRGGVTALGAKKAYPVYADETIELFDVVSISAGVRGTQILVAPGDYLRATKAAVGPIVAAPGGDAD
>NC_021658.1|WP_020737508.1|8011769_8012450_+|universal-stress-protein
MESNPSSTSAATRPFNVLAAVDLSPASRGVLLRALWLANAEETGGEVHVVAVADSGREMLGLQGLAKTSSAADAAARLQELATSVANEFAVPPRSPHVERVVTHLLTGDPAREIVWLAAHVDADLIVMGTHGRTGVKRVLLGSVAERVVRTAGCPVCVVRDKHHDDSWRIPEIEPPCPDCLAERNRTGGASLWCARHKGHVHAHVYSGAETTRTVRRAMRPWGFST
>NC_021658.1|WP_148313929.1|8012598_8013930_-|DUF1552-domain-containing-protein
MRNVKFSRRTMLRGLGYGTVFCSGLFDNVYAQTAPRITRVAMFGYANGSQYQSEPTGGEKDFVLKPHMAPLEAVRNDILVFKNLTLARDPGNAHRSASFSVFGLGAPTSIDQEFAKFLKDTTPLASLEIAVGQTSGDGGVIPGLSQVDGRFIPSVKNPLAAYQRVADRISGGAPAPGNGTPMNTPSAAEQALLRRQSVLDFIKEDVQSFRGRLGPEEATKMDFYLESLRTLERDVGGSIPTDMPSNSCSKLAAPLLSKDTMMNDMPEHSRLYLDIMAMAFACNVTRVASMMWGGGENNEAIKFGDIDISAWHSVSHGDPDRAPGQQIIRLQAYFAQEFRYFIEKLKSFSDGQFSLLDNTAAVLSTQNGSSQLGSAQNFAETDHPPQHAPFVVAGSCGGAWKTGRLLDAGGRNHNDVYLSIARAIGMNVTSVGRASWCRGPLIT
>NC_021658.1|WP_063752029.1|8013939_8015640_-|DUF1592-domain-containing-protein
MPVAELIGVLRSFKGRSLRLAAPLAVVVASGCTGVLGGSPLDSTDPATDSAAECGATPALAKPRIWRLTKSQLANTLRDEFGIEPAALSNLPSEARLDGFANQASQLRIAPLLAEVYFALGEELGAHALQNPDKFGIACDAATLAPGSCLEGFIATTGRKLWRRPLSATEVADFSALFAKTAAQGAGPAGGVTSVVQALFMSPSSLHRTELGTVKDTGAVTPLADHEIASALSYMLWDSAPDAELAALADQGKLRDRTVLLDQAKRLFEARDKASPAMSHFFEQWLELENLPNAVKDADLFPMATPELNADLKEELRLFTDSVLFDAGADRRFDSLFTSTYAFVNERTAPLYGLSGVTGDAMVRRELNPAERRGILTSLPFLWGHAHAQDTALVGRGAYVRAEILCHRVPLPPGGVPNPGKFAEPNATGRQRLGIHASPACAVCHKLFDGIGFALESYDPIGRFRTTEHGQEIDASGSLPLPSEGNKEPGIVFSNFVELVDELAQKPDVYGCFAQQFAAYASGYDLPELDACEKERVVDDFARSQNAIDQLVLSVIASPSFIDRKN
>NC_021658.1|WP_187345646.1|8016557_8016728_+|hypothetical-protein
MDVRVARRGAIGRPISVDRQLGSPRVQAYLARRRVSRVMSLAQAGLDPVGDLPIEE
>NC_021658.1|WP_080682756.1|8020743_8022807_+|hypothetical-protein
MQEIAYDARGERVARRSVPVIEGTPDDERLHDVYEHDAVGREVGHITERSYYADKQRLKGVVTRSGATAVQDLGYGYDERLSLTRRTDALQPQHRNERFRYDPLERLTCAYFSDVESDTAPCALRYDHDPNGNLTFAPDAGTLSYDDPLHPHAVTGAGADSFGYDAVGNQIARPGGERVSYTPFDLPRAITQGARTVSFGYDGDQQRIRKTTPDEEMIYFGDLVERVTDAATGRAEHRYYVRSPERVAAIVTRGGQEPGTRYVHVDHLGSVDALTDEDGDVIERRSYDPFGQRRNPVWGEPTPASFASETTRGFTGHEGDDELGLVNMKGRIYDPRLGRFLTTDPIVQAPLSGQSWNPYSYVRNSPLDHVDPSGFQGVSPEAHAPAAQPLAGVLDSEALGLPPIEVEVVAPPDWVVWVDADADADTAGAGVGAMMAPVDVGTTGTSSGFASYLVTASPEHAGAAGPGTLVSQALLGAAEGTRDLGLGIARSLALNALTFGMYGGYELGGAIWAGYEQDGIFGALNAVNPLYHIGLGAADTALEIDGGDYREAGAAGTKAMILAAATVLGMGRGLGALAEESAAAAATKSAVRVTGDALKTARAEFSAAKPKFWQREAAQNTGNYSAENLARMRSGKAPIGSDGYPMELHHRTPLAEGGTNAFDNLTPLTRTEHRLGPNYHKNHPGLP
>NC_021658.1|WP_080682328.1|8022803_8023247_+|SMI1/KNR4-family-protein
MSFEQLAQRIRSNADREVGTGATEEDIAAAEQALGIPLRGGYRDFLRSFGWGGVSHFELYGLGADVPQYLHLVSITQSERRTMTPRLPPHLIPIMNDGGGNLFCLNTTINEPTIVLWDHEHGEDQQPEWEASTFVEWLDRLLDAVRP
>NC_021658.1|WP_020737515.1|8023382_8023958_+|energy-transducer-TonB
MAIRTGALRRVRPRGPAGNLAALGKIRYVPFALYINSMHERIHPVYEEELAAAREAYPELRGEADMAVLLEIAVIHGDGRLARLGVASSSGSVAFDVVALEAVRRAAPFDAPPQLLVSPGGNVYLHWMFHTDPYQACATFNARPFMLASAPAAAATGQQPVSVHQTGRPRSTPPPLAPAPTTRGVHSEQAP
>NC_021658.1|WP_187345647.1|8024163_8024880_+|energy-transducer-TonB
MERPTGVRAALLLLPLLAMTACAATTTAMPGAAQQDAARQTPSTRFRWACPFPDEADNNGIDTASVVLQASVGIDGFARSVTVLHDPGNGFGQAAAECAMRKVYTPGRDRSGAPVVVSTPPLTVHFVRGKATTASIPGAVQLEGAYPPQLSHSKWGCPYPKEADKNAIDRGTAIIRVYVELDGSSRWAQVLHDSGYGFGSAAAQCAMRRRYAPAKDNSGTPVAAWTPPITIRFIRQRP
>NC_021658.1|WP_148313930.1|8025699_8026476_+|phosphoenolpyruvate--protein-phosphotransferase
MANSAFLARRLTPSGCIIAGTKLAAHREALKAKKIKLSAKVDAAVHAVIAATGAIEALGSTDATMTEIDRGADRCIGAFNSVVDSVERAFDHDGILPLSENEAARRSDALLVRSEVLSSGIDFVRLVYSQQWVRMSAMIKALERKDVKAAVERLGLSAEAGRLRRWTDLYGQKLGVTEAKSADPAIKAVEAWHEAYGTLMVHVHAEYDDDRDETHALLRDRLLSPYEDAADEVRRAEQRARTASAKRKAQAEPEPGPI
>NC_021658.1|WP_049949651.1|8026777_8027773_+|hypothetical-protein
MRRNTRLSIAIPLCIALLSAAAEGRAEAPPAEVARLMAQANAAAREDRLADSRDLWMAVFRLQRSQVAACNIGALSLRLGDAPAAVRWLSICKEIMRAPRTPEERALYESRLSDLARARQLSGELHVIAPAGARITIDGAPAGIDGGKPVPVAPGRHLVRAVLNGGVATAEVDVPRGEAREVVLTLPARPAAPPAPSAALPAPPAGPRAAPVSPAPPSPRPRPDLVAGGFGLSATLAAIGGVMLVGAGKKDEAGHAAARAAGPNRCFRLTRPMCQESASAYDDARAYRGVGIAGLITGGAALGATLGYIFYPRGPAEISVTAGGLTLTSTF

Crispr_ID: NC_021658_29

• CRISPR_ID: NC_021658_29
• CRISPR_location: 8210044-8210153
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_29

Consensus_repeat	Method
CCGAGGCCCGCCTTCTCGGTTCCGCA	CRISPRCasFinder

spacers of NC_021658_29

>29.1|8210070|58|NC_021658|CRISPRCasFinder
CCTCTCCGGCCCCCCTCGCGAGGCGGCGCCGCCACGTCGCGACCTCGCCGCCCCCCCT

CRISPR arrays and Neighbor proteins around NC_021658_29

CRISPR arrays

The CRISPR arrays of NC_021658_29

>merge|NC_021658|29|8210044-8210153|CRISPRCasFinder
CCGAGGCCCGCCTTCTCGGTTCCGCACCTCTCCGGCCCCCCTCGCGAGGCGGCGCCGCCACGTCGCGACCTCGCCGCCCCCCCTCCGAGGCCCGCCTTTTCGGTTCCGCA

>NC_021658|29|25|8210044-8210153|CRISPRCasFinder
CCGAGGCCCGCCTTCTCGGTTCCGCA	CCTCTCCGGCCCCCCTCGCGAGGCGGCGCCGCCACGTCGCGACCTCGCCGCCCCCCCT
CCGAGGCCCGCCTTTTCGGTTCCGCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020737671.1|8208789_8209668_-|ethanolamine-ammonia-lyase-light-chain-EutC	unknown	unknown	gnl|CDD|377583
NC_021658.1|WP_020737663.1|8198976_8199708_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_021658.1|WP_020737669.1|8205248_8206691_+|DUF2252-domain-containing-protein	unknown	unknown	gnl|CDD|313268
NC_021658.1|WP_020737677.1|8214887_8218751_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020737680.1|8222427_8223588_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl|CDD|223890
NC_021658.1|WP_080682760.1|8201231_8202455_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379114
NC_021658.1|WP_020737673.1|8211301_8212069_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737667.1|8203391_8203787_+|hypothetical-protein	unknown	unknown	gnl|CDD|225035
NC_021658.1|WP_020737675.1|8213920_8214184_+|zf-TFIIB-domain-containing-protein	unknown	unknown	gnl|CDD|379195
NC_021658.1|WP_148313951.1|8212796_8213864_+|aminoglycoside-phosphotransferase-family-protein	unknown	unknown	gnl|CDD|270703
NC_021658.1|WP_020737672.1|8210407_8211262_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737664.1|8199760_8201113_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|236532
NC_021658.1|WP_020737679.1|8221193_8222345_+|glycosyltransferase	unknown	unknown	gnl|CDD|226988
NC_021658.1|WP_187345656.1|8204445_8205165_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737666.1|8202478_8203276_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737676.1|8214324_8214606_+|pyrimidine/purine-nucleoside-phosphorylase	unknown	unknown	gnl|CDD|377724
NC_021658.1|WP_148313949.1|8197354_8198920_-|TolC-family-protein	unknown	unknown	gnl|CDD|224455
NC_021658.1|WP_063752038.1|8219328_8220228_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_044986244.1|8206890_8208609_-|tannase/feruloyl-esterase-family-alpha/beta-hydrolase	unknown	unknown	gnl|CDD|284851
NC_021658.1|WP_020737681.1|8223688_8225089_+|ATP-grasp-domain-containing-protein	unknown	unknown	gnl|CDD|227111

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020737671.1|8208789_8209668_-|ethanolamine-ammonia-lyase-light-chain-EutC	gnl|CDD|377583	pfam05985, EutC, Ethanolamine ammonia-lyase light chain (EutC). This family consists of several bacterial ethanolamine ammonia-lyase light chain (EutC) EC:4.3.1.7 sequences. Ethanolamine ammonia-lyase is a bacterial enzyme that catalyzes the adenosylcobalamin-dependent conversion of certain vicinal amino alcohols to oxo compounds and ammonia.	8.65253e-55
NC_021658.1|WP_020737663.1|8198976_8199708_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.31157e-80
NC_021658.1|WP_020737669.1|8205248_8206691_+|DUF2252-domain-containing-protein	gnl|CDD|313268	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252). This domain, found in various hypothetical bacterial proteins, has no known function.	2.56549e-174
NC_021658.1|WP_020737677.1|8214887_8218751_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.18131e-79
NC_021658.1|WP_020737680.1|8222427_8223588_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl|CDD|223890	COG0820, COG0820, Predicted Fe-S-cluster redox enzyme [General function prediction only].	2.03935e-134
NC_021658.1|WP_080682760.1|8201231_8202455_+|ATP-binding-protein	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	1.13241e-25
NC_021658.1|WP_020737667.1|8203391_8203787_+|hypothetical-protein	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	6.8505e-12
NC_021658.1|WP_063752038.1|8219328_8220228_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.39723e-52
NC_021658.1|WP_148313951.1|8212796_8213864_+|aminoglycoside-phosphotransferase-family-protein	gnl|CDD|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	3.65583e-05
NC_021658.1|WP_020737664.1|8199760_8201113_+|HAMP-domain-containing-protein	gnl|CDD|236532	PRK09470, cpxA, envelope stress sensor histidine kinase CpxA.	8.6124e-67
NC_021658.1|WP_020737679.1|8221193_8222345_+|glycosyltransferase	gnl|CDD|226988	COG4641, COG4641, Uncharacterized protein conserved in bacteria [Function unknown].	2.33055e-65
NC_021658.1|WP_020737675.1|8213920_8214184_+|zf-TFIIB-domain-containing-protein	gnl|CDD|379195	pfam13453, zf-TFIIB, Transcription factor zinc-finger.	3.3927e-17
NC_021658.1|WP_020737676.1|8214324_8214606_+|pyrimidine/purine-nucleoside-phosphorylase	gnl|CDD|377724	pfam06865, DUF1255, Protein of unknown function (DUF1255). This family consists of several conserved hypothetical bacterial proteins of around 95 residues in length. The function of this family is unknown.	1.53734e-40
NC_021658.1|WP_148313949.1|8197354_8198920_-|TolC-family-protein	gnl|CDD|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	1.22081e-17
NC_021658.1|WP_044986244.1|8206890_8208609_-|tannase/feruloyl-esterase-family-alpha/beta-hydrolase	gnl|CDD|284851	pfam07519, Tannase, Tannase and feruloyl esterase. This family includes fungal tannase and feruloyl esterase. It also includes several bacterial homologs of unknown function.	7.2708e-104
NC_021658.1|WP_020737681.1|8223688_8225089_+|ATP-grasp-domain-containing-protein	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0

Protein sequences

>NC_021658.1|WP_020737671.1|8208789_8209668_-|ethanolamine-ammonia-lyase-light-chain-EutC
MARAADGQGDGHRNGQGEGQAPAGAITRGPRFGDVRQFCPDEAELAALVAATPAAYGFATAGPRPANAVSRRARRDQAIARAALESALREDELARVAAFRVLTTMAGSKDEHLGSADAGARLSPESAARLAPEGAQVQIVVSDGLSAEAVHHNLPGLLPVLLDGLGARGVTVGQPLLARHGRVKLAEGVAAGLGARLVILLLGERPGSGELASRSLSAYLAYRLAPGVDQEAAAAFSGNPAIGFEYTAIANIHAGGLPAAEAGGALAEKAAQVLARRAAGNRLEALLARDAA
>NC_021658.1|WP_044986244.1|8206890_8208609_-|tannase/feruloyl-esterase-family-alpha/beta-hydrolase
MGLEATLISFASKNGSWTATASALAFGCLAACGGDDGGPAPDTAPPLAVRCAQLANMRIPSASIGLPTTGAVVASTQMKAAHGAVGEHCLVSGDIMPVDPTAPNIKFQVALPADWNSKAVMLGGGGFCGIIPDVAGNPLNTTPDAVTPLGRGYAVFASDSGHQSNPLDGSFALNQEAYANWASDALKKTRDAAIAVVEATYGDAPTKAYFLGSSTGGRQALAVAGRWPADWDGGVALYPARNVTTAMVGGLAMIQAFAAPGAYLDPEERGVLYRAAVAACDALDGASDGVISDVQGCNATFDPSTASLDGVPVRCPDGVDTGDTCLSDAQLTALGEANGEVPFDIPLASGEASFPGFNAFISDLGMASGSPLQPHVAATGLGSAPPGFPVTESMSYGAHFVDGFIRYAVARDAAFDYLTFDGSTGGAFGARLTELSALDVADADLTAFAAKGGKLLMLQGTEDLLVSPRAVEAYYSRLRADMGADEVDAFLRYYEVPGFGHSVSAVFTAGWDYLTALESWVEEGADPATDQIVVDTTGVPGRTRPLCTYPTWPQYRGSGDMDSAASFACTAD
>NC_021658.1|WP_020737669.1|8205248_8206691_+|DUF2252-domain-containing-protein
MEMATVDGSSTVTGEWAMPHLSAEERAARGKAERAEIPRAAHATWKAPPHRRDPIALLEEQATTRVPELVPIRYGRMLVSPFTFYRGAACVMASDLAATTRSGLRVQLCGDAHLSNFGVFGSAERRLMFDINDFDETLPGPWDWDVKRLAASVELAGRDNGFSKSSRSDIVQTTVREYREAMRSFAALRDLDVWYASLDVEQVFDRFRSSVGRKRLHVTERNLAKARTKDSIQAYETLTHEVGGRRRIISDPPLIVPVDEFSKGVAREQIEQQMREILRGYRRTLEADRRHLLERYEFADMAHKVVGVGSVGSRAWIILLLGRDDQDPLFLQAKEAQASVLEPFLGKSEYRNSGQRVVAGQRLMQAASDIFLGWQRVEGVDGVERDFYVRQLRDWKFSVDIAALDRVVLTTYGRLCGWTLARAHARSGDRIAIAAYLGKADSFDKAIAAFAIAYADQTERDHQALAAAVKSGRIQAETGL
>NC_021658.1|WP_187345656.1|8204445_8205165_+|hypothetical-protein
MVLLLAVEGGYRLGAYRLRRSKQEHGAHVLTLVSTTMGLLALVLAFTFGLAATRFEARKQMVVDEANAIETTYLRAGLLPGDRGAKVRGLLRDYVESRLAVVRLGNVEQAMRRAEELHRELWKEAEAAGRDQPSSPVVELFIESLNRTIELNAMRVKVAVRGGIPGVMWTALFTVAILNLAAVGYHAGLVKTRRSPTMATLVMSLSIVLMLTADLDRPQEGALTVSQQAMIDLRRTIGD
>NC_021658.1|WP_020737667.1|8203391_8203787_+|hypothetical-protein
MSFETTRAFNHLVSPHLEDPYPLFEELRREAPVVFNPSFGMWFVSRHEDVAAVVKDPVRFSSAQVLAPLQEPSPALLAILGEDRSGVYPLLSSDPPVHTRVRSLVSKALAGPRLASARSSRAWKARSRSRS
>NC_021658.1|WP_020737666.1|8202478_8203276_+|hypothetical-protein
MVVEGPDDARTVPGLVDRVVEGAVPVLKGKLGRARSFCGLDANAPFVMWSAIHQYPVPRRHGHFGGKPGLEDARTAVLALRCFVARNPQPEAVVLVRDSDGKEAERRQGLEQARQDFAWPFEVLLGVAHPMRECWVLAGFVPESKREETSLAALRKELGFDPTARSHELDASSKTAKKSPKRVLDRLTGDDDEREARCWTEPTLGHLRQRGHGNGLAAFLDEVEARLVPIFSDAGTGDDAGAGLGPPQPCAPEGDEASAKVPSRS
>NC_021658.1|WP_080682760.1|8201231_8202455_+|ATP-binding-protein
MIQQVSFTNFKSLRRVDAGLGRFMVIVGPNGSGKTSILDGLHYLAQATRWPLATLMRGIFAPPNLKSRGTPGPIQLVATGSFHDVTAEVRISVECRDDLNGNSSWRGTVARRWGDAVEETSEAEEGWQLVKSSDPQPNPRPVGKRDVLRTHDLPEMAELAKELGFARKLRLDIEALAAASYSDEEMPRLDTDGSGLASVLADAAARTPEVFQSIQEAARQVIPTLERIRTRRAKVQRQERQEITIDGEEAIQRSVDRFYWGQQLVLDFKGAPDVPAPLASEGTLLVIGLLTALWMEPKPRLLLLDDIDKALHPRAQEELVAQIRKILEMTPELQVIATSHSPYLLDHFDAQDVLLTALLPDGSTACARLADHPDFDRWKTTTRSGELWSFVGEDWVARQASASQEHG
>NC_021658.1|WP_020737664.1|8199760_8201113_+|HAMP-domain-containing-protein
MKSLFLRLLVSLWIAMALLVGLFAVIHGWAFSAESSSLRRRLSTRSVELRAESALSCARDGLSGCEQRLAPLEPRDQRVAVYRSGALVSGEPIDGAPLVEERARRSADGIAVEVGERELVAIVLRRDPSFVAVATGPVRSPWMFFIVPETLPLRLLAIVVVTGLVAVVLARYLSRPIHILRGATQRMAAGDLSVGVAQQLAGADGETLALGRDMDRMAERIEELLETQRRLLRDVSHELRSPLARLNISLELVRRRSPPDVAPAFDRIERETERLNGMIGELLTLSRLESARGMERTERVDLTALVEQLVDDAAFEAEQQGCSVELGARDACSLDGNEELLRRAIENVVRNAVRFTEAGTTVRIDLSCSGGVAEVRVRDRGPGVPEGALGDIFKPFYRVDDHRARGAGGTGIGLAITQRAVLLHGGEVEARNAEGGGLEVALRMPVGAGG
>NC_021658.1|WP_020737663.1|8198976_8199708_+|response-regulator-transcription-factor
MADPPQILVIDDDAELCELLAELLGQEGYAVESARDAISGLARAQEKPFTLVVLDVMLPGLNGFEVLTRLRQSSRVPVLMLTARGEDVDRIVGLEMGADDYLPKPFNPRELVARVRALHRRASHVGHAGAAAAGPGAAEAQSVLTVDDLEVFPAARRVRVRGEEVRLTTAEYDLLEVLVRQAGTVVSREDLARRVLGRRLAAYDRGIDMHVSNLRRKIGPGPSGGERIKTVRNAGYILARERP
>NC_021658.1|WP_148313949.1|8197354_8198920_-|TolC-family-protein
MTNLYTNWTPLETLPPSLGRMTLTRSVPLPWLASLAVIATCTLGSAARAETLTAEQAVGRAASQNPALRAALLEATAARQAVAAEQGARKPTLSASVTGQYAEDLGNGGRGLSGTTTVASDVALRYTTDVGTSLEVGASADKSWGGAARSLEGNGVLRPTTTAQAYVSARQPLLRGAGTDAVLAPIAQAEASAIAAEQERDLAASQTALDVLEAYWELWYAEQAIGVQEQALAAAQRQLNDAKARAETLGTGTRVDVLQFSTSAGSIADALSQARATRSARAIALGRALGMAPREASSLSPTGAPPSLGPLPPIDALTRAAAERSQELAALRADLEAQRARVSAAEDADQVRLDVFTTASVRTPWADDGTSGVSLLGGRPAFTVLGGLDLELPFGGGRASADAARARTQLAAAEARYKARAEAIAAELTSLRVTLEASDEQVALAAETARLAGELAEAERQRLLLGTSTSADVVKAEQTLREAELRKLRALVTALTSRFQLEHAAGALLDRFASVLPRRSS
>NC_021658.1|WP_020737672.1|8210407_8211262_+|hypothetical-protein
MLKHLNLDEMVALLSPWVDDPKQRKLFLSIAEIAALHPRVVEAHEAVVAVQPSGGGDAPSKLRALVDEGNEVDRCHDHLARAVSYGIDTRRELCLAEAPADAARAAQCDAVQKKLFPNGLAILNASPLAEAGNTTRIARLLEEEPEIVDFLKSIPARGKASLLDVVKRWLAKGRELQALERARTELEATQATTPVNKTTIQAARSQWFKVVSLVLSNLEMSRAPARDIEIIRGPVLRASDRAGKRYASAAPEEAPPEREEQGPTPGSSEVEPSGAEISGASELR
>NC_021658.1|WP_020737673.1|8211301_8212069_-|hypothetical-protein
MFKPTHHRFSQLALLGALAVPAFACDGPGEDGLEADLPPAELAADVGALAKGEVALADYFIVTHPDYRRCVAPICGGHFVARVNTSVARCADGTWQEECHMFELDLSGLGLDPSTEAKAKEAFGAGTALVRGELKQVELGGGGSSPADVLVASEIWVGATGNTPKGHFSRVDDSGIDCVTYPCPVFSERSLNTNLSGPLDTVDLSASGATPAQVTSGMSELYETGLLVAGQHGVVTGPAGSMNRLDAAEFYLRVK
>NC_021658.1|WP_148313951.1|8212796_8213864_+|aminoglycoside-phosphotransferase-family-protein
MLSGRADGLVVRIGDVVVKAHAHETDPRDLAARLSLAASPQLGAALLSPLRVPPPGAPPSRGPAPSCSAPVEDALAGLALRVSGRLVTAWPAGEPVSPDDPDAAPWEEAARLLARLHAAALADVAPAGGLPRAGAPGRVARAMARLRAAGRTPAGAAVEAAFARLTPRARGDRAEPSGPRAARWRGDWRGERSGVLVHGDFHLGQVVRLTDARALGAEHTGAPGPKEARREVLCGSRGGCFRLIDIDDLGVGDPAWDLARPAAWYAAGLLPPEVWWRFLSAYRASGGCAVPPEGDPWPALDAPARALAVQSAALAVAAASRDGRALDALDELDEVETALVDACRRMACVDSPPDV
>NC_021658.1|WP_020737675.1|8213920_8214184_+|zf-TFIIB-domain-containing-protein
MLQCPKCHAAMRTYNRNGVHIEQCDGCRGIFLDYGELEALTRLETQWAPAPPPAPMHGAPPTPAWGAPHHHYGHVRHKSFAKMLFSS
>NC_021658.1|WP_020737676.1|8214324_8214606_+|pyrimidine/purine-nucleoside-phosphorylase
MLKHNSYFNGSVQSVGFERHGRRQTVGVIDAGEFHFSTEAPERMTVVAGELAVRFDGSQEWRAYPAGTSFEVAGKSGFDVKAAHPTGYLCEFL
>NC_021658.1|WP_020737677.1|8214887_8218751_-|protein-kinase
MRAGNVIDGRFEIVELAGAGGMGHVFRAYDLTTGETVALKVLQNAATQDSSRLAREAQALASLRVPGVVRYIAHGVTELGHPYLAMEWLTGETLSQRLARQAFTLDESLKLARRVATTLGSVHRLGVVHRDLKPSNLLLVGGAIDRVTLIDFGVVRMSGIDQQLTMPGAILGTPGYMAPEQARGEAQVDARADVFALGCLLYKCISGRAPFRGARGLAVLVKVLLEEPPSLRWLREDVPEALDELVTRMLSKSPEGRPSDGNAVAAELAALMDPAAISVRPPASSIRPPELTTGERKVMCLVLARDGRAPAAAEAALPEVDEQARAQALSATAARYQGQLELVEARLPLVVLSGAGATTDLAARAARCALAVQALLGGAPVSVVTGRAEIASRMPIGDLIDRVVQLLPERRAPSRAAAIRIDEVTAGLLGARFEITTNEAGQWLHGAREGPDEVPLLLGKATSCVGRERELSLIRDELARCVEESTPSVVLVTGPAGIGKSRLRHELVRAIREDGEPVEVWLGQVDPMSAGSSFGLLAHALRRAMGLSEADAVEERRRKVRARVERHASLDAARVATFLGELVGAPFPDDDVQLRAARRNPMLMGDQLRLAWEDFLRAECAVHPVLLVLEDLHWGDLPTITMVDAALRNLKDRPFMVMALGRPEVHELFPKLWDERRGHKLRLAGISRRSSERLVRQVLGERESPALVATLVERADGNAFYLEEQIRAAAAGKGADLPETVLSMVQAELDALDVGARRVLRAGAIFGESFSRNGVAALVGRAEVDRLLAELEARELIVRRSVEGAPEVIEHRFRHALVREAAYGMLTDHDRRLGHRLAGEWLERTGAADAMALAEHFERGGEPARAATATLRAAEQALLGSDLGAVIERVERGVARGASKATAGALRLCQAEAHLWRGEFALAERRGMEALERLSPGSAPWFSALTQMILAASKRGNHDQVERLLRVAQTTEPRRSARTARSVCLCAGAGRLLFGGRYQLADELLDAIEQDAEETDLEVEVLARLHEARAYRAMAGGDPGSSFAGFEAALAAFEQAGDRRNACWARNNLGSCYAELGDFEGAEAALRASLADAERMGLSDARLGALLGLGPVLARLDLVEEARRTAEEAIATSQGLGDARREGAARTCLARILLQTGDLGGAEREARAAVAILYGAPPLRAFAYAVLGRALLDGGQVVDALAATTEAFCLLESVGAEVGESLVRLAHAEALSACGHRREAMMAIASARERLLDRARKIRDPAWRARFLGNVPDNAATLEIERRWLGA
>NC_021658.1|WP_063752038.1|8219328_8220228_+|serine/threonine-protein-kinase
MSIVPGTVLLQRYRVVRHLRREGLGEVFSAEDASAGRRVAVKVLGEPPVRLDPGGVLSAPERMPLEEAEARFRREAAACQRLRGPHTLPSIDGGKDPEHGPLLVFELREGELLSDRLARLGPIPFAAVHPLVEQLWLAIAELHEIGIIHRDISSTNVLLDRGPDGERLTLLDLGSCKPPPALSDEAVSLPGRCLGDFRFAPPEQLAKGKTVDHRADLYAAMTVVFQALTGELPYAARNLMMLADLKTRTPPRRLGNLMPPPVDKHVEVFVNRGLAHSPDRRFANIAEVIDGWRGLRPAS
>NC_021658.1|WP_020737679.1|8221193_8222345_+|glycosyltransferase
MTTPTYRYVFLGLSITSSWGNGHATTYRALLRALAARGHHVLFLERNLSIYDQHRDLPNPPYGAIEQYSSITELRDRFSRAVREADLVVVGSFVPEGATVGAWITEEARGKAAFYDLDTPVTLGRLAHGDHAYLTPALIPRYDLYLSATGGPTLERLERSHGAVRARALYCAADTDVYYPQPTPMRWDLGYLGTYSDDRQAAVERLLLEPARRMRRGRFAVAGAQYPASLAWPENVTRTEHLPPDEHRIFYNAQRFTLNLTRRAMVESGWSPSARLFEAAACGTPVLSDTWPGIETFFQPGEEILLVRTPEDVLRKLREMKEDKRLTVGQRARQRVFAEHTAMHRAEALERYTREALEAASRTRARRDRDGQLAAAHVETQSG
>NC_021658.1|WP_020737680.1|8222427_8223588_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MRSTPLHPVARLPEEWSTSLAARGERSFTAKQVFHWIHRRGILDPAAMTNLPARLREHLAAEGLGEVLTPERVHRSEDGTRKLLLRLRDGATIETVLLPSVSGPGSQAQLDADAAAADDDEDDDAEAGAAPRVRVTQCISTQVGCAMGCGFCASGVAGLKRHLGAEEIAGQVLLGRAMLEEGEDLRNVVYMGMGEPLHNYENTARSLRLLTHPEGINLSTRRVTVSTSGLVPEIARLGADFGGQIALAISLHAADDETRSALMPINRKYPLDELLAALRAYPLPRRRRITIEYTLVAGQNDDPAEARRLAKLLRGLPVKINLIPMNPIEASSLGPPAQERVAAFQEVLTQAGYSCFVRRRRGDDVSAACGQLVLLGAKPKVRRALG
>NC_021658.1|WP_020737681.1|8223688_8225089_+|ATP-grasp-domain-containing-protein
MLKKILVANRGEIACRVLRTCKRLGIATVAVYSDADAGAPHVAMADEAVRIGPPPVKDSYLVIHAIVEAARATGADGIHPGYGLLSENEAFAEAVLEAGVTFIGPPPAVLHVFGDKILAREQARGADVFPPPGTGGPVDPADLESAQRAAESIGFPLLVKAAGGGGGIGMQIVAEPGKLARALTACSDRGRAAFGDPRVYMERYIERPRHIEVQVLCDGKGGAVALGERECSAQRRHQKIVEETPSPAAFFEGEAGEARRRSLHESALRVVTSAGYVGAGTVEFVAAESGELFFLEVNARLQVEHCVTEMCTGLDLVEHQIRIASGEPLAPEVREHAYRGHAIEARLYAEDPAKKFAPQPGRIAALRWPAAGDDLRIETGVAEGLEVTPFYDPLLAKIVAHGATRGDAIARLDRALAETTIELAGPAGPAATNLAFLRQILADADFRGGQYDTRFAEALAAGKKAG

Crispr_ID: NC_021658_30

• CRISPR_ID: NC_021658_30
• CRISPR_location: 8246902-8247007
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_30

Consensus_repeat	Method
CCTGCACCGCCGTCGCCCCGGCGTCCTG	CRISPRCasFinder

spacers of NC_021658_30

>30.1|8246930|50|NC_021658|CRISPRCasFinder
CGGTGTCTCCGGCGCACGCGCGTCCTGCGGTGTCTCCGGCGCAGGCGCGT

CRISPR arrays and Neighbor proteins around NC_021658_30

CRISPR arrays

The CRISPR arrays of NC_021658_30

>merge|NC_021658|30|8246902-8247007|CRISPRCasFinder
CCTGCACCGCCGTCGCCCCGGCGTCCTGCGGTGTCTCCGGCGCACGCGCGTCCTGCGGTGTCTCCGGCGCAGGCGCGTCCTGCACCGCCGTCGCCCCGGCGTCCTG

>NC_021658|30|26|8246902-8247007|CRISPRCasFinder
CCTGCACCGCCGTCGCCCCGGCGTCCTG	CGGTGTCTCCGGCGCACGCGCGTCCTGCGGTGTCTCCGGCGCAGGCGCGT
CCTGCACCGCCGTCGCCCCGGCGTCCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020737700.1|8245707_8246700_-|phosphotransferase	unknown	unknown	gnl|CDD|270702
NC_021658.1|WP_020737694.1|8240799_8241558_+|GTP-cyclohydrolase-II	unknown	unknown	gnl|CDD|238348
NC_021658.1|WP_020737698.1|8243392_8243971_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379115
NC_021658.1|WP_148313954.1|8241686_8242178_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737711.1|8259369_8260386_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|223135
NC_021658.1|WP_148313955.1|8252146_8253673_-|sialate-O-acetylesterase	unknown	unknown	gnl|CDD|164795
NC_021658.1|WP_020737690.1|8234994_8236392_-|homoserine-dehydrogenase	unknown	unknown	gnl|CDD|235783
NC_021658.1|WP_020737708.1|8251315_8251891_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NC_021658.1|WP_020737699.1|8244262_8245483_+|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|173848
NC_021658.1|WP_020737697.1|8242504_8243365_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239488
NC_021658.1|WP_020737705.1|8248892_8249375_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|377770
NC_021658.1|WP_148314894.1|8250210_8251140_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|225130
NC_021658.1|WP_020737706.1|8249758_8250148_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737691.1|8236448_8238383_+|type-VI-secretion-system-contractile-sheath-large-subunit	unknown	unknown	gnl|CDD|377573
NC_021658.1|WP_020737688.1|8232768_8233953_-|chorismate-synthase	unknown	unknown	gnl|CDD|235438
NC_021658.1|WP_044986247.1|8254969_8259043_-|DUF4150-domain-containing-protein	unknown	unknown	gnl|CDD|372665
NC_021658.1|WP_020737704.1|8248209_8248881_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_021658.1|WP_020737693.1|8239089_8240538_+|hypothetical-protein	unknown	unknown	gnl|CDD|223727
NC_021658.1|WP_020737710.1|8253885_8254899_-|hypothetical-protein	unknown	unknown	gnl|CDD|171499
NC_021658.1|WP_020737703.1|8247448_8248021_-|glutathione-S-transferase-family-protein	unknown	unknown	gnl|CDD|223698

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020737700.1|8245707_8246700_-|phosphotransferase	gnl|CDD|270702	cd05153, HomoserineK_II, Type II Homoserine Kinase. This subfamily is composed of unusual homoserine kinases, from a subset of bacteria, which have a Protein Kinase fold. These proteins do not bear any similarity to the GHMP family homoserine kinases present in most bacteria and eukaryotes. Homoserine kinase catalyzes the transfer of the gamma-phosphoryl group from ATP to L-homoserine producing L-homoserine phosphate, an intermediate in the production of the amino acids threonine, methionine, and isoleucine. The Type II homoserine kinase subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	1.56255e-26
NC_021658.1|WP_020737694.1|8240799_8241558_+|GTP-cyclohydrolase-II	gnl|CDD|238348	cd00641, GTP_cyclohydro2, GTP cyclohydrolase II (RibA). GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the precursor molecule for the synthesis of the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which are essential to cell metabolism. The enzyme is present in plants and numerous pathogenic bacteria, especially gram negative organisms, who are dependent on endogenous synthesis of the vitamin because they lack an appropriate uptake system. For animals and humans, which lack this biosynthetic pathway, riboflavin is the essential vitamin B2. GTP cyclohydrolase II requires magnesium ions for activity and has a bound catalytic zinc. The functionally active form is thought to be a homodimer. A paralogous protein is encoded in the genome of Streptomyces coelicolor, which converts GTP to 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (FAPy), an activity that has otherwise been reported for unrelated GTP cyclohydrolases III.	6.18667e-112
NC_021658.1|WP_020737698.1|8243392_8243971_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	2.54848e-09
NC_021658.1|WP_020737711.1|8259369_8260386_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl|CDD|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	2.47111e-171
NC_021658.1|WP_148313955.1|8252146_8253673_-|sialate-O-acetylesterase	gnl|CDD|164795	PHA00370, III, attachment protein.	2.41146e-06
NC_021658.1|WP_020737690.1|8234994_8236392_-|homoserine-dehydrogenase	gnl|CDD|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NC_021658.1|WP_020737708.1|8251315_8251891_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	9.2992e-13
NC_021658.1|WP_020737699.1|8244262_8245483_+|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|173848	cd01159, NcnH, Naphthocyclinone hydroxylase. Naphthocyclinone is an aromatic polyketide and an antibiotic, which is active against Gram-positive bacteria. Polyketides are secondary metabolites, which have important biological functions such as antitumor, immunosupressive or antibiotic activities. NcnH is a hydroxylase involved in the biosynthesis of naphthocyclinone and possibly other polyketides.	1.97423e-68
NC_021658.1|WP_020737697.1|8242504_8243365_-|phosphatase-PAP2-family-protein	gnl|CDD|239488	cd03394, PAP2_like_5, PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.72641e-14
NC_021658.1|WP_020737705.1|8248892_8249375_-|nuclear-transport-factor-2-family-protein	gnl|CDD|377770	pfam07080, DUF1348, Protein of unknown function (DUF1348). This family consists of several highly conserved hypothetical proteins of around 150 residues in length. The function of this family is unknown.	1.39862e-91
NC_021658.1|WP_148314894.1|8250210_8251140_-|MBL-fold-metallo-hydrolase	gnl|CDD|225130	COG2220, COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only].	1.11477e-22
NC_021658.1|WP_020737691.1|8236448_8238383_+|type-VI-secretion-system-contractile-sheath-large-subunit	gnl|CDD|377573	pfam05943, VipB, Type VI secretion protein, EvpB/VC_A0108, tail sheath. EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/VipB and TssB/TssC. On contact with another bacterial cell the sheath contracts and pushes the puncturing device and tube through the cell envelope and punches the target bacterial cell.	2.20002e-45
NC_021658.1|WP_020737688.1|8232768_8233953_-|chorismate-synthase	gnl|CDD|235438	PRK05382, PRK05382, chorismate synthase; Validated.	2.57109e-179
NC_021658.1|WP_044986247.1|8254969_8259043_-|DUF4150-domain-containing-protein	gnl|CDD|372665	pfam13665, DUF4150, Domain of unknown function (DUF4150).	8.0395e-28
NC_021658.1|WP_020737704.1|8248209_8248881_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.05969e-26
NC_021658.1|WP_020737693.1|8239089_8240538_+|hypothetical-protein	gnl|CDD|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	3.69166e-09
NC_021658.1|WP_020737710.1|8253885_8254899_-|hypothetical-protein	gnl|CDD|171499	PRK12438, PRK12438, hypothetical protein; Provisional.	0.00954902
NC_021658.1|WP_020737703.1|8247448_8248021_-|glutathione-S-transferase-family-protein	gnl|CDD|223698	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	4.55912e-40

Protein sequences

>NC_021658.1|WP_020737700.1|8245707_8246700_-|phosphotransferase
MAAPGADVTAPVDRAVLARALALYGADPASCRFLGGFESQVFEARYPGGALVLKLGDPEHRSPDAVEAECEWLEFLTARGVRAAPAIRAADGRYAALLGEPGQAVCARAYAKAPGAPLSAGDLTPGVATAWGRLLGRLHAATRAYVPPSSRRRHAWHEDGDFANARELLPEDEREPIGGRIERLVAELRALPTDPDAFGLVHTDAHFGNVLKDGDALTLIDFDDCAYEWFASDLGIVLFYAAIDPLGPGRPIELLRRFRDRFLDGYARENALSARWLAEIDRFMKLRELVLYTAIRRVGRREALDAWCRAYLERHGPRIVGDRPVWPEGG
>NC_021658.1|WP_020737699.1|8244262_8245483_+|acyl-CoA-dehydrogenase-family-protein
MSEPRRSPERERLLAAVERVRGVAVAHAEASERQRTLAPAVVDALRSSGLFAAAAPRAVGGAESDPLTQLEVFEAMARADTSAGWSLMISALLAALAGGSLPDEGARQVFAGPFPTFAGLQVPSGVARRVSGGYVLEGRWAFGSGVRHARWVFTSAIVAPEGGAPPAGPPEMLSLAVPIEQVAIEDTWDVAGLRGTGSDHYRIEGAFVPEALTCAFPGAPRRRGGALYAIPLLALLAAGHVGFALGVGRRALDEIAAVAPRRIKAWPQLALGSHAAFHMDLGRAEAKLAAARAYAFDALGRMWDRARAGEGLAIEDWAEIRLVQTYVTEVAAEVAGFAYRAGGGSALYAASPLQRCFRDMHAATQHIAATDDAYEFAGRARLGIAELHPLLAPREAAGGERDRRGG
>NC_021658.1|WP_020737698.1|8243392_8243971_-|TetR/AcrR-family-transcriptional-regulator
MLEEALALIEEQGNARFTLREVARRIGVSHAAPYRHFADKRALMTELAVQASTELAAQISAALEQAGGALRARFLAAGYAYVRFALEHPAPFHVMYSSEVDAEDPRVAAATSRSLGLLLGFIEEAQRAGAFPPGDPMALAVPIWAMHHGLATLAASGALSKAGPAELRRVVDDAHARLLDGLLLAAPGPSRA
>NC_021658.1|WP_020737697.1|8242504_8243365_-|phosphatase-PAP2-family-protein
MRPAAIALPAFLAALSPAAAAAAEPPPELAYRPEVDLPIVVVGGAAWVASELAKKGLAPEPCRWCAANALDTSVRDALVWRGNPNTAHDLSNVAVVAVAPAAALGLTALAAWYDGRSENTAADLMIVAEATVVAMNLNQVTKYIVGRERPYSHFDNPDVLRAGVGLSGALPNDDNLSFFSGHATATFALAAASGTVASMRGYRAAPWVWANGMAIAALSGYLRIAGDRHYFSDVLTGAVFGSAAGVLIPALFHGPRRGVAGPDTHGFRISLAPARGGVGAGVAGTF
>NC_021658.1|WP_148313954.1|8241686_8242178_-|hypothetical-protein
MHVVHHSSRHRWIAGGLAAAFPVLLAGCSDQALGAPVPGEGPPRAAAPGQLAPRGAGQRGAAPRPAAPPAALLERDELLREAGRLAEVRAALARSPEAPLALLDAHRAEFPDGRLAAERELVAIDALLRSGRAGGARARAEAFLAQFPSSPHAGRVRRLIDAP
>NC_021658.1|WP_020737694.1|8240799_8241558_+|GTP-cyclohydrolase-II
MTEPMNPLLELVTRDREHDCDGYGQASVCVRVVGVAELPTRAGHFRIVAFWNNRDAKEHIAMVHGDVVGASNVPTRLHSECLTGDVMGSLRCDCRDQLLEGLKKIKSMDRGILLYLRQEGRGIGLINKIRAYALQDQGLDTVEANLALGFRDDERDYAVAAHMLHSLNVRSVELITNNPNKVQQLKQYGVSVAGRIPHVIPPNDHNRFYLETKAKRSGHFIDMWGKPHLTEQSDPVVVDGMSPPDSEPTPAS
>NC_021658.1|WP_020737693.1|8239089_8240538_+|hypothetical-protein
MKPRTQQNIRSNHPFAGRRAVVIGGSIAGLVAARVLADHFDEVDVIERDGIPDDLREARKGAPQARHLHGLLARGERILNDLFPGFTEDLIRDGAVAYDFGVGLAWHHLGAWKPRFETGVQTVCMTRPLLEAHVRRRTFALPGVRRLDEREVVELSASPDRSRITGVVVRRRGAPGGVEELRADLVVDASGRGSRAPAWLEALGYGRPDESTIQVRVGYAGRQYRPRDPAELPWTSLYVLGSPSDSRRFGCIAPVEGGRWIVVLAGLFGDHPPADPDGFLEFARGLPNDAVYRALLTAEPLTDVATYKFPAHLRRHYERMARMPEGFAVLGDALASFNPVYGQGMTSACLQALALGAALEEQRRRAGPGAIAGLARRYHAAAAKAVDLPWQMSTGEDLAYPETEGRRPRLQPILRWYTGMLHRAAQVDREVYVRFVRAMHMLDGPEALLDPGLFLRVLRAGRSASAPAVAAAAPARRQPAGA
>NC_021658.1|WP_020737691.1|8236448_8238383_+|type-VI-secretion-system-contractile-sheath-large-subunit
MAETIKGVLGDEFRFHVGEDGGAVERGPLLPLRVLVVADLTPRDPHNAGASPPAGAARVDAGKFDNLFAALRPRIAIEVPSVLAGGRPARVDLSPTGLKSFRPDALCAEVPLLRSLLDGRRVLDRLRDGSATLEQARAELDRLWGGSPLVRDILGLLPAAGAGAPPGRPAAPAAERPAAPAPASDVDALLSMVDLGGGGGDAGAAPAAAAPGGPDPRPAEGGRFAELIATVAASARPRAGQPARPAEALAQLERAIGAQLGAILQHPEVRRLEEAWRGLSLLVDRVKAAEGVRVEVVSARPDEAAGALARVLAQTASTEPPASVAIVDVAIDGSAAALARLEEIARVAEAHALPAVVNGDPRLLGVEGLGGVERLDNKAALFGAPHRAPWRAAAARPSMRWVAIAMNRVLGRMPYDKSTSRIREAAIVEQPGDEGGRVWISPAYVVGALIAASFRETAWPCRIAGAKGGGVLGDLPVHEVKGAYEGDEGVAIPTEAFVSTDTQRDLSKSGVLLLASAPNSDAVYVLTAPTAYVPPEKLTYDGSTAEPEARLDRVSLVDQLFVARVVQFLRALAAKLPADSDPAEVQPVVEGALWTLFENAPPASIELAVKAGRGQGGAEVSVTVRPRRFLGVGLDEVSLEMPLG
>NC_021658.1|WP_020737690.1|8234994_8236392_-|homoserine-dehydrogenase
MKTEGGSPLNLNPEPHAASDRRRLRGGAPIQIGLLGCGTVGGGVLRLLAENSGYLAERAGVPLVVKRVVVRDLEKERVSALDRGLLSTNPAEVVDDPSIDLVVEVMGGETPARELIERAIDRGKGVVTANKLLLAAHGPALLARAAARQVDLAFEGAVGGGIPIIRTLRDAFASDWVERVTAIVNGTCNYILTRMRDTGASFDAALREAQDLGYAEKPDPSLDVDGHDAAHKLIVLAMLAFGAQVDAAQVHTSGIRTIEEADHLYADRFGYTIKHLAIGRDLGDAIELRVHPTLIPKQSVLANVSGVLNAVLLEGRAVGPSLVYGRGAGDLPTAVSVVSDVLDVARSIASGVAGMQGRGMSIKPRRVRPLSEIVSRYYLRFAVEDRPGVMGRIAGALGDAGVSIEQIVQQGPTKRSSGAAAREPAVDVVLITHDAQEGLVRSALDAVAREEFLREPVHLFRIEEP
>NC_021658.1|WP_020737688.1|8232768_8233953_-|chorismate-synthase
MTQLRWLSAGESHGPELVATVEGIPAGMPLLAEDIDEDLARRQRGYGRGGRMKIETDRVRLVAGVRGGETLGGPIAMVIENRDHASWAGRMGPEPFPEPPEALTRPRPGHADLAGGLKYARKDLRDVLERASARETAARVAVGGVCRKLLRSVGVEVFAHVLSIGAVRSTISAASGAGDLPLAELRERARASDLACVDAEAAQAMRDAIREAAHRGDTLGGVFEVIATGLPPGLGSHVQWDRKLDGRLAQALMSIQAIKGVEIGIGFEAARISGSEVHDPIAYDQGAHAFTRPSNRAGGLEGGITNGMPLICRAAMKPIATLKRALPSVDVRTKEQFDAAFERSDVCAVAAASVVGEAMVAITLAAALLEKFGSDSLTELSRNVDTYLQQVRSY
>NC_021658.1|WP_020737703.1|8247448_8248021_-|glutathione-S-transferase-family-protein
MKLYYNPRSRAAITRWMLDECGAAYDLVPIDFEKREHKAPEFLKINPAGKLPALVDGEAKLFENAAICLYLADKFPEARLAPPIGSPQRGRYLSLMVYSTSQLEPAMGDHLMKVETTPQRGWTNFETAMDVVEGELGGGPYLFGDWFTAADVMIGSMFIWKRLWGGPPGRPKLEAYVDRLMARPHMKIFK
>NC_021658.1|WP_020737704.1|8248209_8248881_-|class-I-SAM-dependent-methyltransferase
MSTSPNKPEIATAYDRWSATYDNDPNRTRELSAAVLRERGLALAGRDVIEIGCGTGLNTQWLAERAGSVLALDFSEGMLRQARARVGSPRVRFAQHDIRSPWPAALGSSDVVIAMLVLEHIEHVDAIFAEAARALRPGGELFLCELHPVRQMRGGQANFVNRETGEPERVPAFLHDVSEYVNAGLSSGYELVHLGEWRDAEAARNDPPRLLSVHLRLRAISPS
>NC_021658.1|WP_020737705.1|8248892_8249375_-|nuclear-transport-factor-2-family-protein
MSQEPAASRPPLPPFTAETAARKARLAEDAWNSREPARVAQAYTVDSRWRNRAEFFQGREAIEAFLHRKWQRELDYRLIKEVWAFTGDRIAVRFAYEWHDDSGTWYRSHGNEQWEFDAHGLMRRREASINDVRIAAEDRKFHWPLGRRPDDHPGLTELGL
>NC_021658.1|WP_020737706.1|8249758_8250148_+|hypothetical-protein
MSSDPPGADYLDAIFAAIRGGAAQLTAMKAWLGSAQRAASSSSWRFQFLAAARAAHRRAGAYLDETEERLRRLGPDDQVPAPLDRLPRNVAAMRADLRAEEQHLHRLETEATARREPSSAGARGKRSAS
>NC_021658.1|WP_148314894.1|8250210_8251140_-|MBL-fold-metallo-hydrolase
MLALVLAACAPANRADASAPPAAASAGAGPSAGAPADADASSGRLQWRGGPTAILERDGLRLLTDPVLGPRGPAAFALPKHPSTGVENAPVARYTDPPAEPLGRLDVILLSHNHADHFDAVARETLPKDVTFVLPPDAADAARAAGFTRLTPLDWDGETVIPTRAGRLRILAVPANHSHDAALDATLGKGNGYVLRWEGATPYSIYWTGDSVFTEPMRAVAARFAPIDLWLPHLGAVGVDGARGLRTMDAEEAVAAAALLRPRHVIPIHHTTFGHYREPVTAFVQRAATKRLPAHIHVPTDGAWMPLPR
>NC_021658.1|WP_020737708.1|8251315_8251891_-|TetR/AcrR-family-transcriptional-regulator
MSDARSHILEVAERLFYAEGYRAVGVDRLIAEAGVAKATFYRHFRTKDELLVAVLDARDARFRAWLAGRVEALASDPLDRPLAVFDALSERFAANDFRGCAFLNTMVEVASRSHPAHEASQRHKQRLIDYLEGLLREAGVPDAAALAPQLLLLIDGATVTAVREGGPGAAARARSLAEVLLATARPRRRRR
>NC_021658.1|WP_148313955.1|8252146_8253673_-|sialate-O-acetylesterase
MRKPLVLGLGSSGILVLLLMGLGCASSSDSSSGTGGDGGSGGQSATSSGSGAGGASASTGSGGAADGGGGAGTGGTGGDAAGTGGSGGGATPAPAWDWTGIVGTGQSLSVGAEANPPLGTRQRFGNLKLSLGNATVPPFDPESSALSLVPLVEPIRPFATTYPSAYPKNLYGETPHTAMADQISSLAKAAMIGDHVTVHTVVGESGQPMSVLRKGAAEVVSGDTTMGRAYAATLFEAEAIAKLAGKAGKTFGVGAIIITHGESDAGSPTYEDDLVKLWSDYNQDIPPLTGQTRSIPMLVSQQHSVHLEVGSRSTSTLAQWRVGVSHPGDILCSGPKYQYPYANDHIHLNANGYQQLGEKYGQVYFEKVVLGKDWQPLQPTRVERSGNVVTVHFHVPVPPLVWDTALPPPHQTALTEWAQGRGFELWSGNTRIEITGVEIDGDSVEITARDLPASGVMVGYAATTDGEAHAMPGGTTRWGQLRDSDPFVGSVTGKAQPNYGVAFEMSVP
>NC_021658.1|WP_020737710.1|8253885_8254899_-|hypothetical-protein
MFCAAFALAWERLRARFGPIHMDPQPALADALNAATLGAEVVDPAWSVSGAGFGGEGVVEALRAELFSKFPDAKPHYLPDAVPADALVAYGYLSKVLKFETRFAVREGTFKDSRVRAFGLDGNPFGADPARRSQVVVHDWAAPGDFVIELVADDPDSRVLVAQVAPAETLAATVAGALGRLDRLRGDARQLAADEPLVIPRLKLDLEERFRELEGRPLIGEELSGVRFDEAKQRVQFHLNEGGAGATAEAILGSYGPPPRSFWVTAPFLVLLQRRGASAPYLAAWVESTAWMEVLGPVPPPPPGWGPPTGFGAPPGFGAPPGFGAPPGFGPPPSGAA
>NC_021658.1|WP_044986247.1|8254969_8259043_-|DUF4150-domain-containing-protein
MGKVTALHMDTITEKSGHQMTGMAVSVCLTPAAPSPLPIPYPTMGTVAEGIIDPCMRTKIEGAKILTVGGCMKACHGNEPGTLKEVVSLNTGGPCFPWLGAPNVLIELGMAGITGSMGQMNKSITVGAGASASGAGGGGGGGGGGGGGAGGPGGGGPQGGSNAGGGGGGSNQGAGPPSPPAAPGADGQAAAGHPVDVVTGAMFTPPETDFLLPGPLPVRWIRTYRTSSVLRECGIGRGWSHALGWQAEIQDDRLTLIDETLRSTTLAVPPSDVEVLLPFGRRVFWDGDALVVDLDDGVLRVLRRGPAPGTFRLAELRDRAGNLAEVAWDEREVVQIVDSVGRRAWLVREGQLKSWWVAATGADGVEHTKRLVTYELDTNGDLVRAIDAGGVETRYAYDDEHYLVLEQQPGGLRYHFVYADVSGERRCVETWGDLEGADALQEIGAPEASMAARPKGLFHMRFEYGPGPHETTVIDGLGYRFRYKGNALGLVERYQDPVGQQKDLSYNAVGQVVRSTTSDGTERSTYDARGRLASFTDAMGRSFSLKRREDGAIVEVRDPAGARYAFTVGDHGEVLERADPLGATTRYEHDRRGQVIAIVAPDGTVESLEHDAHGNLAARTLPGGGTARYTHDLFGQLVRVEMPGGAVYELDYDSRGLPVRVRAPGGVVTERAFNDARRPVSTRHPGGGVSSARYVGHLVVEEVQADGARYRFGYDARGRLAWVRNPAGESLTIERDACGRVIRTRTFSGVETTYEHDARGRIVRAEVAGATVRKIAYDACGDVIRREDGDVVTTLDYDDRGFVRRGTRGATEVLLERDAAGRIVREEQRVGGWRYRVERAFDAKGWATAKRYSTGWQVQVGRGPSSDVESITVESAAGVERILREVDALGKETARVREGGYAIRTERDTQGRPVATALEDAAGRPVRARRYVWSKTGPIEQIIDSAAGVRTYELDVFGRPLAVSGLGAQEQIRYDPNGTPLRSGEDRVGPGGRLLRAAGVAFTWDAQGRLASRAPEGGSAGWTYEYDGLDALARATRGDGLVVQYHVDAFNRRLGEVRSDGGSTWFGWDDQTQVEEVSSSGASVRRVFADDEITPLLEGSAAGPWRSVVTDATATPWLTVDPTGAATGQDLGAFGGVTRQEGPFTAIRFAGQRHDELTGLTYHRARYYAQELGTFTTPDPLWIDASMFELAFVPNVTLWVDPLGLVILLLSDDPQCVYGANARAWATGHRIVHYSELGNPRALANDNDLYVYGHGSPGTIHYADRGGNFTGSTMTGQQLASSIRGAGFTGRNIHMTVCHGGTDPPGQPGGSIAQSVANATGATTVGCVGAKMFDHPTIPGVTVAGAGGTMQPFTRRP
>NC_021658.1|WP_020737711.1|8259369_8260386_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MSKRIAINGFGRIGRCIVRALSQRGVSDIELSALNDMASPETLAHLYNYDTVHGRAERRAVAADGRLLIDERPVRVLAEKDPAKLPWRELGVDIVLECTGVFTDRDKAAAHLAAGARKVIIGAPAKGHDATIVLGVNTEEYDGSAHTVLSCGSCTTNCLAPVAKVLLDAFGLERGLMTTTHAYTNDQVLLDVPHRKGDLRRARAAAQNIVPTSSGAAKALSECLPALAGRFDGLSMRVPTMDVSVVDLTFESTRPLTKDAIHAAMKRASEGPLRGILGYTEEPLVSSDYLGDPRSSIFDATLTQVMGDRFAKVFAWYDNEWGFSNRMVELAQLVAAKL

Crispr_ID: NC_021658_31

• CRISPR_ID: NC_021658_31
• CRISPR_location: 8415642-8416722
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 14 spacers

Consensus repeat of NC_021658_31

Consensus_repeat	Method
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	PILER-CR
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CRISPRCasFinder
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CRT

spacers of NC_021658_31

>31.1|8415678|38|NC_021658|PILER-CR,CRISPRCasFinder,CRT
ATCCAGAGTGGCTCCGGTTCCGGCACAGCGAAAACCGC
>31.2|8415752|36|NC_021658|PILER-CR,CRISPRCasFinder,CRT
GACCACCGCGAGCACGCTTCCGCCGCCCGGAATCAC
>31.3|8415824|39|NC_021658|PILER-CR,CRISPRCasFinder,CRT
CGCTGTTCCTTGAGCCACCGCTGGACGAGGGCGATCCCG
>31.4|8415899|37|NC_021658|PILER-CR,CRISPRCasFinder,CRT
CAGGGGGTCCGGCGCGCGCCGCAACGGTCCGCGCCAA
>31.5|8415972|44|NC_021658|PILER-CR,CRISPRCasFinder,CRT
CGGCCGAGGTCGCGCTGCGCGCTGACCACATCGAGCAGGAAGAG
>31.6|8416052|44|NC_021658|PILER-CR,CRISPRCasFinder,CRT
CGGCCGAGGTCGCGCTGCGCGCTGACCACATCGAGCAGGAAGAG
>31.7|8416132|43|NC_021658|PILER-CR,CRISPRCasFinder,CRT
TCCAGGACGATGTACGACCCCTCAGGGGCGGTCTGGAAGGACT
>31.8|8416211|35|NC_021658|PILER-CR,CRISPRCasFinder,CRT
GCACTGCGTTTGCACTGCTCGATCATGCGTCTGAA
>31.9|8416282|38|NC_021658|PILER-CR,CRISPRCasFinder,CRT
TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
>31.10|8416356|38|NC_021658|PILER-CR,CRISPRCasFinder,CRT
TAGACCTGGCGAACGTTGCCAGTGGCCTCGACGATCTT
>31.11|8416430|37|NC_021658|PILER-CR,CRISPRCasFinder,CRT
ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
>31.12|8416503|35|NC_021658|PILER-CR,CRISPRCasFinder,CRT
AATGCCTGGCATGATTCATGACCTCCCGTTGGGTG
>31.13|8416574|37|NC_021658|PILER-CR,CRISPRCasFinder,CRT
CACTTCCACCCGAGGGCCTACGGGCAGCCGCCCCGCA
>31.14|8416647|40|NC_021658|PILER-CR,CRISPRCasFinder,CRT
GATTACGAGAGCGACTCGGACGTGCCCTTGGGAAGCGACG

CRISPR arrays and Neighbor proteins around NC_021658_31

CRISPR arrays

The CRISPR arrays of NC_021658_31

>merge|NC_021658|31|8415642-8416722|PILER-CR,CRISPRCasFinder,CRT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCATCCAGAGTGGCTCCGGTTCCGGCACAGCGAAAACCGCCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGACCACCGCGAGCACGCTTCCGCCGCCCGGAATCACCTCTCCGCCGCTGAAAGGTGGCGGCCCCATTGAAGCCGCTGTTCCTTGAGCCACCGCTGGACGAGGGCGATCCCGATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCAGGGGGTCCGGCGCGCGCCGCAACGGTCCGCGCCAACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCGGCCGAGGTCGCGCTGCGCGCTGACCACATCGAGCAGGAAGAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCGGCCGAGGTCGCGCTGCGCGCTGACCACATCGAGCAGGAAGAGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTCCAGGACGATGTACGACCCCTCAGGGGCGGTCTGGAAGGACTCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCGCACTGCGTTTGCACTGCTCGATCATGCGTCTGAACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTACTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCTAGACCTGGCGAACGTTGCCAGTGGCCTCGACGATCTTCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCTCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCAATGCCTGGCATGATTCATGACCTCCCGTTGGGTGCTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGCCACTTCCACCCGAGGGCCTACGGGCAGCCGCCCCGCACTCTCCGCCGCTGAAAGCTGGCGGCCCCATTGAAGCGATTACGAGAGCGACTCGGACGTGCCCTTGGGAAGCGACGCTCTCCGCCGCTGAAAGGCGGCGGCTCCGTTGAAGC

>NC_021658|31|2|8415642-8416722|PILER-CR
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATCCAGAGTGGCTCCGGTTCCGGCACAGCGAAAACCGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GACCACCGCGAGCACGCTTCCGCCGCCCGGAATCAC
CTCTCCGCCGCTGAAAGGTGGCGGCCCCATTGAAGC	CGCTGTTCCTTGAGCCACCGCTGGACGAGGGCGATCCCG
ATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CAGGGGGTCCGGCGCGCGCCGCAACGGTCCGCGCCAA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGCCGAGGTCGCGCTGCGCGCTGACCACATCGAGCAGGAAGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGCCGAGGTCGCGCTGCGCGCTGACCACATCGAGCAGGAAGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCCAGGACGATGTACGACCCCTCAGGGGCGGTCTGGAAGGACT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCACTGCGTTTGCACTGCTCGATCATGCGTCTGAA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TAGACCTGGCGAACGTTGCCAGTGGCCTCGACGATCTT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	AATGCCTGGCATGATTCATGACCTCCCGTTGGGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CACTTCCACCCGAGGGCCTACGGGCAGCCGCCCCGCA
CTCTCCGCCGCTGAAAGCTGGCGGCCCCATTGAAGC	GATTACGAGAGCGACTCGGACGTGCCCTTGGGAAGCGACG
CTCTCCGCCGCTGAAAGGCGGCGGCTCCGTTGAAGC

>NC_021658|31|27|8415642-8416722|CRISPRCasFinder
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATCCAGAGTGGCTCCGGTTCCGGCACAGCGAAAACCGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GACCACCGCGAGCACGCTTCCGCCGCCCGGAATCAC
CTCTCCGCCGCTGAAAGGTGGCGGCCCCATTGAAGC	CGCTGTTCCTTGAGCCACCGCTGGACGAGGGCGATCCCG
ATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CAGGGGGTCCGGCGCGCGCCGCAACGGTCCGCGCCAA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGCCGAGGTCGCGCTGCGCGCTGACCACATCGAGCAGGAAGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGCCGAGGTCGCGCTGCGCGCTGACCACATCGAGCAGGAAGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCCAGGACGATGTACGACCCCTCAGGGGCGGTCTGGAAGGACT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCACTGCGTTTGCACTGCTCGATCATGCGTCTGAA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TAGACCTGGCGAACGTTGCCAGTGGCCTCGACGATCTT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	AATGCCTGGCATGATTCATGACCTCCCGTTGGGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CACTTCCACCCGAGGGCCTACGGGCAGCCGCCCCGCA
CTCTCCGCCGCTGAAAGCTGGCGGCCCCATTGAAGC	GATTACGAGAGCGACTCGGACGTGCCCTTGGGAAGCGACG
CTCTCCGCCGCTGAAAGGCGGCGGCTCCGTTGAAGC

>NC_021658|31|6|8415642-8416722|CRT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATCCAGAGTGGCTCCGGTTCCGGCACAGCGAAAACCGC
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GACCACCGCGAGCACGCTTCCGCCGCCCGGAATCAC
CTCTCCGCCGCTGAAAGGTGGCGGCCCCATTGAAGC	CGCTGTTCCTTGAGCCACCGCTGGACGAGGGCGATCCCG
ATCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CAGGGGGTCCGGCGCGCGCCGCAACGGTCCGCGCCAA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGCCGAGGTCGCGCTGCGCGCTGACCACATCGAGCAGGAAGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CGGCCGAGGTCGCGCTGCGCGCTGACCACATCGAGCAGGAAGAG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TCCAGGACGATGTACGACCCCTCAGGGGCGGTCTGGAAGGACT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	GCACTGCGTTTGCACTGCTCGATCATGCGTCTGAA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TACGCCGACCACGTGCGAGGGTTCCGGCCCGCCTTCTA
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	TAGACCTGGCGAACGTTGCCAGTGGCCTCGACGATCTT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	ATGCTCATCTCCATCCTCCCGCGCGCCTCGGCGCTCT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	AATGCCTGGCATGATTCATGACCTCCCGTTGGGTG
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	CACTTCCACCCGAGGGCCTACGGGCAGCCGCCCCGCA
CTCTCCGCCGCTGAAAGCTGGCGGCCCCATTGAAGC	GATTACGAGAGCGACTCGGACGTGCCCTTGGGAAGCGACG
CTCTCCGCCGCTGAAAGGCGGCGGCTCCGTTGAAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_044986263.1|8429073_8430021_+|GlxA-family-transcriptional-regulator	unknown	unknown	gnl|CDD|227311
NC_021658.1|WP_020737825.1|8400358_8401939_+|amino-acid-permease	unknown	unknown	gnl|CDD|132469
NC_021658.1|WP_148313981.1|8424265_8425141_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187346077.1|8419861_8420449_+|hypothetical-protein	unknown	unknown	gnl|CDD|237865
NC_021658.1|WP_020737830.1|8411707_8412649_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148313979.1|8417186_8417369_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737834.1|8420568_8421546_-|PEGA-domain-containing-protein	unknown	unknown	gnl|CDD|285503
NC_021658.1|WP_020737819.1|8395159_8396008_+|DUF1989-domain-containing-protein	unknown	unknown	gnl|CDD|163257
NC_021658.1|WP_020737828.1|8410238_8410430_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737820.1|8396004_8396676_+|DUF1989-domain-containing-protein	unknown	unknown	gnl|CDD|132465
NC_021658.1|WP_020737827.1|8403794_8409581_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_021658.1|WP_020737818.1|8394147_8394846_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_021658.1|WP_044986259.1|8412916_8414932_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NC_021658.1|WP_148313980.1|8423264_8424170_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737840.1|8428032_8428809_-|glucose-1-dehydrogenase	unknown	unknown	gnl|CDD|235816
NC_021658.1|WP_020737835.1|8421912_8423184_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020737839.1|8426534_8428010_+|GDL-motif-peptide-associated-radical-SAM/SPASM-maturase	unknown	unknown	gnl|CDD|188428
NC_021658.1|WP_020737829.1|8411029_8411680_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_021658.1|WP_020737838.1|8425888_8426494_+|DUF1842-domain-containing-protein	unknown	unknown	gnl|CDD|370176
NC_021658.1|WP_148313978.1|8401962_8403729_-|response-regulator	unknown	unknown	gnl|CDD|223715

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_044986263.1|8429073_8430021_+|GlxA-family-transcriptional-regulator	gnl|CDD|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	5.95491e-91
NC_021658.1|WP_020737834.1|8420568_8421546_-|PEGA-domain-containing-protein	gnl|CDD|285503	pfam08308, PEGA, PEGA domain. This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteristic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	0.000207604
NC_021658.1|WP_187346077.1|8419861_8420449_+|hypothetical-protein	gnl|CDD|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	0.00527212
NC_021658.1|WP_020737819.1|8395159_8396008_+|DUF1989-domain-containing-protein	gnl|CDD|163257	TIGR03425, urea_degr_2, urea carboxylase-associated protein 2. A number of bacteria degrade urea as a nitrogen source by the urea carboxylase/allophanate hydrolase pathway, which uses biotin and consumes ATP, rather than my means of the nickel-dependent enzyme urease. This model represents one of a pair of homologous, tandem uncharacterized genes found together with the urea carboxylase and allophanate hydrolase genes.	1.31336e-97
NC_021658.1|WP_020737829.1|8411029_8411680_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.74513e-73
NC_021658.1|WP_020737825.1|8400358_8401939_+|amino-acid-permease	gnl|CDD|132469	TIGR03428, ureacarb_perm, permease, urea carboxylase system. A number of bacteria obtain nitrogen by biotin- and ATP-dependent urea degradation system distinct from urease. The two characterized proteins of this system are the enzymes urea carboxylase and allophanate hydrolase, but other, uncharacterized proteins co-occur as genes encoded nearby in multiple organisms. This family includes predicted permeases of the amino acid permease family, likely to transport either urea or a compound from which urea is derived. It is found so far only Actinobacteria, whereas a number of other species with the urea carboxylase have an adjacent ABC transporter operon.	1.29373e-169
NC_021658.1|WP_020737820.1|8396004_8396676_+|DUF1989-domain-containing-protein	gnl|CDD|132465	TIGR03424, urea_degr_1, urea carboxylase-associated protein 1. A number of bacteria degrade urea as a nitrogen source by the urea carboxylase/allophanate hydrolase pathway, which uses biotin and consumes ATP, rather than my means of the nickel-dependent enzyme urease. This model represents one of a pair of homologous, tandem uncharacterized genes found together with the urea carboxylase and allophanate hydrolase genes.	1.26532e-132
NC_021658.1|WP_020737827.1|8403794_8409581_-|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	6.1774e-120
NC_021658.1|WP_020737818.1|8394147_8394846_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.88983e-09
NC_021658.1|WP_044986259.1|8412916_8414932_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000154266
NC_021658.1|WP_020737840.1|8428032_8428809_-|glucose-1-dehydrogenase	gnl|CDD|235816	PRK06500, PRK06500, SDR family oxidoreductase.	6.48631e-90
NC_021658.1|WP_020737839.1|8426534_8428010_+|GDL-motif-peptide-associated-radical-SAM/SPASM-maturase	gnl|CDD|188428	TIGR03913, radical_SAM_domain_protein, Y_X(10)_GDL-associated radical SAM protein. This narrowly distributed protein family contains an N-terminal radical SAM domain. It occurs in Pseudomonas fluorescens Pf0-1, Ralstonia solanacearum, and numerous species and strains of Burkholderia. Members always occur next to a trio of three mutually homologous genes, all of which contain the domain pfam08898 as the whole of the protein (about 60 amino acids) or as the C-terminal domain. The function is unknown, but the fact that all phylogenetically correlated proteins are mutually homologous with prominent invariant motifs (an invariant tyrosine and a GDL motif) and as small as 60 amino acids suggests that post-translational modification of pfam08898 domain-containing proteins may be its function. This view is supported by closer homology to the PqqE radical SAM protein involved in PQQ biosynthesis from the PqqA precursor peptide than to other characterized radical SAM proteins. [Unknown function, Enzymes of unknown specificity].	0
NC_021658.1|WP_020737838.1|8425888_8426494_+|DUF1842-domain-containing-protein	gnl|CDD|370176	pfam08896, DUF1842, Domain of unknown function (DUF1842). This domain is found at the N-terminus of proteins that are functionally uncharacterized.	1.27691e-33
NC_021658.1|WP_148313978.1|8401962_8403729_-|response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.92212e-50

Protein sequences

>NC_021658.1|WP_044986259.1|8412916_8414932_+|hypothetical-protein
MVAPRLSPLTLALLAVSCGPAAGPAPAALAPAVVAIPPAPPAETPARAAGEPAVDPSSPLSLPAAASPPPTWVEPPLAEQDRARAHQNPFREHREVAVGEHVSIAAAKGDVASAAGGPGVFAVHEKLGVVGPLKLPARSTWVGLAAGTAGPQDDALYAATPDGALHRAAGVHDALRPDGFAPRGSVAGATAWDAAGGLVAAAAGARVSVSADEGQTFTEAVVASGKRVRAVLVRPDGVLAAVVEAPSRGQRPGPPDTFLSLDRGRTWKRSAFQPRAIERAGSWIWNGDATCPAVLSRDGQQWTRAASAEALYDRPRLDGALYVSTAIRAGAAGSFRSAVAPPPPEPPARGAAAVGREPPCKRDGASGVGGVVGGVWGAYGPACEGALCLLHADPPEPPPTRTWIAAFGDGLCDPARVPPGGACAAHLARPPTFAVVDQLAGAVTPVAAPEGCPQPVALHSAAGVGVLVCRGAGGGAAIFVRGATGPWHAEGSQAIPAEALGPMAAAPDGTLLLRGPTPPASAQGREPLLALVRSPLPLGAAQAWRRIAAPDGVAALPAPGGAALLAISPAASAGGRLELALDRPGRPVLSLVRDVEVYQDLTRMEVRDDGRVRFRVLPKPAPEVPGRPRLPPPGPRDARWHELTRGGELVVEATATPAGPAEERRSGPAGR
>NC_021658.1|WP_020737830.1|8411707_8412649_-|hypothetical-protein
MGDADITLRHLARRRPEDLVRPFVAESRPVEVLGWVDSQVTNIERRLDKALRPRIGGEPRVLHVEFCFSLRDDVPDRIFEYLGFLFAALRLESPGAPVPPIESVAVVLSGRRRRLPNAGKRRIAWPGRPFSGARFRIDAVYQRTVSELRARGSVLWLVFAPLARNATAAALREVVAEIHAGAKGAEERAELYTALLVMATIDPWGHTLLKELIAMVEDKEEGLLRRTPIIGEMIIEAERRAEQRGEKRGEEKAIVALLGRLFARRIGRRPTDEEERSIVERARAIGPGEVEDALLDLEGEALVRWLAEPMRPS
>NC_021658.1|WP_020737829.1|8411029_8411680_+|response-regulator-transcription-factor
MTKLGVFVVDDHPIVRDGLKALINAQPDMTVVGEAADGLSAVEAVTELGPDIVLMDVTMPKLGGAQATERIKQARPEVQVVALTGYEDKANVQPLLKAGASGYVLKGARGAELVRAIHAVAAGGVYLDPSMTAHVVSSVVGRTFGDHGSASELSEREAEVIRLIAEGHAIKEIAARLDLSARTVETYKVRAMEKLGLTSRADTVRYALQQGWLKSE
>NC_021658.1|WP_020737828.1|8410238_8410430_-|hypothetical-protein
MLKRGAPAFQEHVHWEETIAQLVTQGRLAPGQGGLLEEAGDLRFAQRGALRLVDGAGDAVIGA
>NC_021658.1|WP_020737827.1|8403794_8409581_-|AAA-family-ATPase
MLKVPCGEPAIPRALAKPVLVPEPWGDTSLACVLDQGPLPVEVALRLGAALARSLGEVHRRGLLHRDIKPHNVLVDAERTRTCLLDFGLATRWTPKLAAQMPPEAVSGTLAYMAPEQTGRMNRAPDARADLYALGATLYQMLTGALPFDATDTLELIHAHIAQTPVPPHERAPERDIPEAASAIVLKLLAKSPEDRYQTASGAAWDLERAARAWVETGTVAPFPLAKRDWDDRVRAPSRLFGRERDSAALAALFDQACGGATVLALVTGPSGVGKSALVQALQGQVRAQRGIFAAGKFDQLQRSTPYAALAQALRTVVRRRLADPAEVLDRWRQAFQEAAGPNGQILVELMPELAHVLGYPKPLVELGPMEAKRRFQTTVLRFVRTLATAEHPLLLFIDDLQWADAASLALLGELLKEPAGQHLLVVGAYRDEAVSPEHPLNALLSSSTAPGAVTGRIALPPLGAEAVAAMVADMLDRPKAEVEELSRLIKEKTDGSPFFVGQFLQLLHERKLLVRDAETGRWQWQREAIERAGITDNVVALLTRRLQRLSPELQRALQTAACVGDRFDAELLAHLLGQQAETTSALLAEAVREGLLVREGEQVEEGYAFVHDRVQQAAYEALTAEERLSLHLGIGRALRARYGVACADGELFATLYHRNRATERLTEAEEKRDLSEQNLRAGQRANASAAYAQAVAFLGTAASLLGEEGWTEAPETTFEVHLVMAEAHWLAAQIDEAERLFLRCLERARDPLERARVASVLIVFLHVTDRFAQGIELGLSALAWLGRPLPRTPEEQQALFDALITEIEPALQQMTVEDWKALPMSTDRAHALRCRILEVLGPCAAFWMPSLSRCCWPMLVLETLRYGLTKSSFAGCVCTALLLAYLLGKLPLGRRLNEPMLALLDQYDVARAAARFNSTVAAMYWTPPPKMRELYARAARTGAEERDLVAEAFSEIHGAMFQLIAGDDLDRVTRDLDRMAYRDPMAVDFRNIIARSVAALSQAPTAHAVEQTLAEIARPARDATAMALLTATMAMAGWTGVHFGADAWAVEAVLAVESEWQVSWGTPMLIALTFALCVAGAHALPTATAERRALLEARLAFHGARLALWAQGCPESFEAVRLLMEAGRARAREEHEEAGRLYDQAIEQARDHDLVNTEALGLRLAGEHRLARGHRALARAYLSAAHDAYLRWGARAAAARLAQRYPDSIAASGRPALAADEPPGGAPVPTSTTITDRTLHAYLDIASALRAAQALSGERNLGSLVGHMLRLLAEHSGAERAVLALVQGGELVIAALLTVNPQQVELALDEPVAGSTRLPATLVQYVARGKEPVVLGQAACDSRFDEDPYLLAHRPGSVLAVPLVHQGRLSGVMYLEHPSVEDAFPQARVELVTLLGALAATAVENATFYTELSAYSERLAREVEQRTAELEAAKEAADRASRAKSEFLSSMSHELRTPLNSVLGYAQLLGRLPGLPAKAADSARIIHTAGTHLLSLINDVLDLAKIEAGKLDLHPTAADLPTLLRTVTNLCRVRAEEKGLSFAYERVGPERLGVRADEKRLMQVLLNLLGNAIKFTEHGGVTLRVEVLEPPEDQWRTVRFQIKDTGPGIAPEHLGRIFEAFEQVGDEKRHADGTGLGLTITKNLIERLGGSIEVDSQLGQGTVFTATLRLLEATTAQRSAGLSWEAIIGYEGERRTILVVDDNAENRALLRDLLQPLGFELLEADSGERALALALDRTPDVILMDLAMPGMDGYEATRRLRQRPELARTAIIASSASISEADRHESLSAGCDDFLPKPVQAGALLELLRGTLQLEWQRRAGQGAAVTMPLMADAELCTLTLPPAHELARLVELADRGFVSQVLNELDRLEEADPQLGAWIGQVRAVARSFQIKRLRGLLQAQLRYITAAPPIAQPDQQQRRARRGET
>NC_021658.1|WP_148313978.1|8401962_8403729_-|response-regulator
MNRTSDPGVPSYTILMVDDVPESMAATVAQLEERGFRVAIAQDGEDALERAELISPDLILLDVLMPGMGGFETCRRLKASESTKGIPVVFMTALGETAQKVAGFEAGGVDYVVKPLEIDEVLARIKTHLALSAMRAELEAQNVQLRQEIEKRKRLEAELRCAHDMLERRVAERTSELAAANGLLKQEIGERKRAEETLRESQGLLQAIIDNSTAMVYVKDLQGRYLLSNRRFRQLCHATVESIVGRTDHELFPPEQAESFRSFDRRVLEAQQPLEAEEVVPQDDGMHTYISVKCPLFDAEGMPYAVCAISTDITERKRAEEERERLLASEQAARSKAETADRLKDEFLCTLSHELRTPLTSILGWAHILLRATKSDAATVERGLRVIERNGMAELGLIEALLDVSAILCGKVDLKPQPVSLAEVIQAVLDTVAPAAEAKGVCISLSLSSKTSRVWGDRGRLEQIVNNLLSNAIKFTPSGGRVDVSLEEVGATSQLRISDTGEGISADFLPHVFEKFRQANSSTTRWRRGLGLGLSIVRDLVIMHGGEVRAESAGEGRGAVFIVDLPLMPVVEETAAPRSTDAGEARSV
>NC_021658.1|WP_020737825.1|8400358_8401939_+|amino-acid-permease
MRDPISTGAPDHRGAAGAGAAAQDSSDADDLARLGYRQELRRDLGSLSAFAAGFSYVSILTTVFQLFVIGYAFGGTRFFWTWPVVFLGQLAVALNLAEVGSHYPVAGSVYQWGRRVSPGAPGWLAGWLKLVGDVVSVAAAAIALQAILPSVWGGFQLLGGDPSLTSRDGAANAVLLGAGLVALTTAINMAGVRAMAWVNDVGVMAELGGVVLLIGALFLHAVRGPAVVLEPIYGPSPPLGTGAAGLLAAALMPAYVLYGFDSAGSLAEETQSPRRIIPRAILKAVVASGVGGALLLLAALMAAPSLTDGRLATEGLAYVVVSALGPTLGKVFLVDVALAVCVCTLAIQTGASRLAFSMARDGALPCAPALARVSPRTKTPVVPAIAVGALACGMLVVNYGEAQLFVLITETAVLLVNLSYLLVTAGMLLRRLRGWPGGSGAPAGVFSLGRTGLALNVAAVAWGVALIANIAWPRRGGESTWMEYFPVIGVAGTLAVGLAVFAATQRPSGARVAVSPPRESSASLLS
>NC_021658.1|WP_020737820.1|8396004_8396676_+|DUF1989-domain-containing-protein
MIPAAPGKPVAALRDPALAGLPGALVSDEIVPARAPWAKIVRAGEILRVIDLEGNQAVDFLAYVLADTAERYSAADTIVAQRNIFLTTGAKLRSNRGRVMMTIADDSCGRHDTSGGACSCESNTVRYGHHTKHQHACVENFLMAAAPYGLGKRDLVGNINWFMNVPVEADGTLGIVDGLSAPGKHVDLRAELDLLLLVSNCPQINNPCNGFDPTPIRMAVVRP
>NC_021658.1|WP_020737819.1|8395159_8396008_+|DUF1989-domain-containing-protein
MSETATTYAARAHARAQEGSVVETQPTVPSTSIGDPPPGVEARDVLWDETLGAGGYAARTLPVGSRLRIVDVEGDTCVALMLHRADRPIERLCLADTVKLQWQAYPGPGYLLLSDMGRALASVLEDTAGRHDTFCGTSLPGEIASRYGSDAHGGALRSGRERLLLALAKHGLAERDLPTPINLFKGVRIEADGAITFLPDASRPGAHVLLRAEQDVLVSVAAVPHRLDPRPAYRAGKVRLTAWRGRPAPDDDPVRNATPEARRAFENTAEELAVALRAGGAR
>NC_021658.1|WP_020737818.1|8394147_8394846_-|TetR/AcrR-family-transcriptional-regulator
MGRPRKAPQRSELAPREQILEAAGRLFAERGVVDVSMLEIAQAAGLRQSSLYYWFRRKELIVAEILQQVNRLPLSYARKLEASGGAADVQLWRFVRFDVETVCGFPLEITEIHRFSERDPEAFATYWAERRALTEAVAAMIGRGVGEGAFREVDAYLCALTVLAQDESVQNWYRPGGAGRIHPLAASDPAALGYRPEQIAELVADQTVGGLLARPSRLATLRQMAVAADGEG
>NC_021658.1|WP_148313979.1|8417186_8417369_+|hypothetical-protein
MDIIGERKVVFQPAGAEHEREISLRISRPQQRPDDGWEVQIDISDPANRGNYRRCGEPTG
>NC_021658.1|WP_187346077.1|8419861_8420449_+|hypothetical-protein
MGASSPGSPSPPSPAAITLSRTIARAPRLKIIAIDDLPSRAEASAATARTPKITDVASFSATTASSPPRTRTGIPSGGAMTVDAFGPANDPPYDHSSPPSQRRLPQRSTPEGSVISSANAPPQAYTRRVGASPSPRPLAASPIACCIVFTGALFVPGLSSSPCSLTNTPHSSSAGAVAGSPSQGDFGRERQTRSS
>NC_021658.1|WP_020737834.1|8420568_8421546_-|PEGA-domain-containing-protein
MKDLVGRARNARKLGKWHEAYYAYKAAFDAAEAVPSAIGERAELAGELGLCALALRKYREAAEHLTWSLEQGHALTDEVRLRFEVGQARAAFYLVRVLLSVDPPDAEVLIDGKSIGRTERIYKLFLDPGRHMVRARAPGREDALHVVSASAGSEIEIAMQLPRLPVSGAKEAPAAPEAASASPAARPQASSPWASWPGTLRIAGIGLTVAAGSLGAAFMVRASTTDGDLDERNARLDAAGVSPGVCREPPKPATCSELTRLRRERDLFAGLGTAMVVTSGLVGAATLASFFADLSFLRTEPTKARLALTPTVTPAQLGLVAYGAW
>NC_021658.1|WP_020737835.1|8421912_8423184_+|hypothetical-protein
MPPPPPPAPQPQPPSPPKPPFSLADGAIAALVATGYGVPPVAALLFGATVLAQLGGALILVVALGIAGWLALTVWTYRAIRRRGRRPFQVASEVLALLLLPAWGLAYSHEANHACEVQACDAGTTAFRPLAEPEVYGLLALHALTALAYAISRRRPAALPGPAELAIHAALLLGLALHALLAVHFGPWVVAGLLVPPLFLPCIAPVITVVLYAVELRARLVRRGVEASAPAPLAGADAAYRAGPPQVPLPPPPAIHRPTLWRALAASPVLLGIHAVVHAAWLGHPSAALQVFTRTCGYTLSQLPIVELPGDCHYLCTVAARGHAWLVRPIRLGRRGGTPILVNRQLAIANAFEDLLHERWPRFGRAARRLYDRLGLPVSRYIRAAWAADLVYLAMKPLEWAFYLALLLLDPRAPESRIDRMYR
>NC_021658.1|WP_148313980.1|8423264_8424170_+|hypothetical-protein
MLPSRIAGTPRDDFGYFNVSLALDASPARQSRLDTMDFHRSRSIRAGASSADRSTKIRRRFLHMVCGAAALLGGVLHGCGGDGGDPGGIGLEDFVRVESELHCRLSYDCCSAAALDNPFLATSKETCVQFRYGIQQARLLPTLRASVAAGRLVYHPDRMRACVDRLNGAGCAATDADWLCLFDVFEGQVPLGGECTVEHDCENWHCVKPDPDAEVGTCAPWSPDGAVCETFVECDSGRCDIFGTDTCGPRLPEGSDCVLGPDCETYNCPEDTGTCGPPLDDNGCPVDGLLLDNKTPAGSWY
>NC_021658.1|WP_148313981.1|8424265_8425141_-|hypothetical-protein
MCARTVAVDDDIGSYCVTKADGAYRCWGSSASTDAVDAPPLPDEIYRRVQLTRYGLIGLTEDGRLRAAEFTIPESPSQVVAFRQTNMGGDVGVCSLRSDGVFEMFLYNPREPDGPSTRTHSVEGGPFSRVYCAWEGMYAAVRADGTVLSNFATAPPGDGFAELALSIGIFCGLRTDGTISCHRPPADRVGNLDVGPDLPAFSSGRYRSITATVGVVCAIDEQDALVCKRYDGRDMPVPPARYVFAEGGYNLVCAVRVDGSTACFRHGGAGNLDLEDVSDFAPVEPPLDPGW
>NC_021658.1|WP_020737838.1|8425888_8426494_+|DUF1842-domain-containing-protein
MTNTPSRTGLFLVNYDIGTPAIGSPNLTLSLTVNTVHKVVNGFGQITQTVSPPLDLHTRVDGSFTYMTVMPDVTHILVVATGYPPVQWPPGGGVGPVLQPNFELRMVLDKGWQGGTASYSFVEASGRRVEIEKAVVTSSGQRGGPIHTLYGPAMQEAAASGDLARMKQLAAQAEQHLSQSAEIESALAALKAEIGRSERAR
>NC_021658.1|WP_020737839.1|8426534_8428010_+|GDL-motif-peptide-associated-radical-SAM/SPASM-maturase
MSRAVRDRETDDFRRNVPVHAVWEITLACDLKCRHCGSRAGARRDRELDTAECLEVVAALARLGTRELSLIGGEAYLRSDWIDIIRAARAAGMRCAVQTGGRNLTEARLAAAVGAGLLAVGVSIDGLAPLHDELRGVPGSFSRAIDAVRRARAHGIAASVNTQIGARTMDDLPALLDAIAAAGATHWQIQLTVAMGNAVDNDAVLLQPYQLLELMPLLDRLYREGLDRGLLMVVGNNIGYFGPFEHRLRGVGDESVHWTGCAAGQNVIGLEADGTVKGCPSLRTSGYAGGNVRDLRLEDIWNHAEEIHFGRLATVDALWGFCRTCYYADVCRGGCTWTADSLFGRPGNNPYCHHRALELDRRGLRERVVKKREAPGAPFAIGEFELIVEPVPGREGASPAPPVTAATGGLIQLRRRRDGAAAPRDGRVPPQLAPCRACDRYIYPREATCPHCGADVARAAAAHAEVVQRRRALIERLERALSGAAAAASRG
>NC_021658.1|WP_020737840.1|8428032_8428809_-|glucose-1-dehydrogenase
MRLKGKTAFITGGNSGIGLATARAFIAEGAKVAITGRSQKTLDAAAAELGEDVLAIRADVQDVPSIERAVVRAVEAFGKLDIVFANAGISGATPLGETSLDAFESIVRTNLTGAFFTVQAAAPHLNDRASVILNGSVHAVMGMPGRSAYAATKGAVRSMTRVLAAELAPRGIRVNQVTPGAHRTPIWSDVAPDAAAASALEERLATAIPLRRMGDAREVAAVALFLASDESSNVTGAEIVIDGGMTGAPFGAPVHGAR
>NC_021658.1|WP_044986263.1|8429073_8430021_+|GlxA-family-transcriptional-regulator
MRTIGLVVYPGFSAMSLAVTTVFETANRHVGTLEYKLTLLSERGGPVATSLGVEIQTAPFGRRAFDTLLVAGNSEGSPGPPGVARYLRAAARRTRRIAGMCTGAFVLAEAGLLDGRRATTHWYFARRLQQKHPSVAVDDDRIFIADGPIWTSAGMSAGIDLALALVEADLGVEVARMVARKLVVYHRRAGGQSQFSALLDLDAKSDRVQTALAYAREHLGADLSVERLARAAHLSPRQFSRVFREETGQSPAKAVERLRVEAARLMMESGRFSVDEVARENGFGNRERLRRSFVRAFGQPPQALRRAAGQLDGRS

Crispr_ID: NC_021658_32

• CRISPR_ID: NC_021658_32
• CRISPR_location: 8722041-8722151
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_32

Consensus_repeat	Method
GCAGGCCGAGCGCGTGGGCGACAAGGCCGAGCAGCT	CRISPRCasFinder

spacers of NC_021658_32

>32.1|8722077|39|NC_021658|CRISPRCasFinder
CGCGCGGGAGGGCCAGGAGCTCGGCCGGGAGGCGCGCGA

CRISPR arrays and Neighbor proteins around NC_021658_32

CRISPR arrays

The CRISPR arrays of NC_021658_32

>merge|NC_021658|32|8722041-8722151|CRISPRCasFinder
GCAGGCCGAGCGCGTGGGCGACAAGGCCGAGCAGCTCGCGCGGGAGGGCCAGGAGCTCGGCCGGGAGGCGCGCGAGCAGGCCGAGCGCGTGGGCGAGAAGGCCGAGCAGCT

>NC_021658|32|28|8722041-8722151|CRISPRCasFinder
GCAGGCCGAGCGCGTGGGCGACAAGGCCGAGCAGCT	CGCGCGGGAGGGCCAGGAGCTCGGCCGGGAGGCGCGCGA
GCAGGCCGAGCGCGTGGGCGAGAAGGCCGAGCAGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020738046.1|8718453_8718813_+|phage-holin-family-protein	unknown	unknown	gnl|CDD|377198
NC_021658.1|WP_044986293.1|8718906_8719890_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381312
NC_021658.1|WP_148314014.1|8719955_8721740_-|DNA-mismatch-repair-protein	unknown	unknown	gnl|CDD|213210
NC_021658.1|WP_148314013.1|8713364_8715533_+|anthranilate-synthase-component-I	unknown	unknown	gnl|CDD|237429
NC_021658.1|WP_049949678.1|8723099_8724668_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020738058.1|8734267_8738875_+|glutamate-synthase-large-subunit	unknown	unknown	gnl|CDD|236968
NC_021658.1|WP_020738038.1|8707378_8708230_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_021658.1|WP_020738039.1|8708267_8709200_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_021658.1|WP_044986292.1|8716847_8718200_+|argininosuccinate-synthase	unknown	unknown	gnl|CDD|235434
NC_021658.1|WP_148314016.1|8726600_8727662_-|3-oxoacyl-ACP-synthase	unknown	unknown	gnl|CDD|236475
NC_021658.1|WP_020738053.1|8727934_8728561_-|endonuclease-III	unknown	unknown	gnl|CDD|223255
NC_021658.1|WP_044986296.1|8733189_8734035_-|metallophosphoesterase	unknown	unknown	gnl|CDD|224327
NC_021658.1|WP_020738044.1|8715858_8716686_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738042.1|8711899_8713180_+|isochorismate-synthase	unknown	unknown	gnl|CDD|224091
NC_021658.1|WP_044988940.1|8709322_8710552_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270453
NC_021658.1|WP_020738057.1|8732451_8733189_-|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl|CDD|225002
NC_021658.1|WP_044986295.1|8729312_8730548_-|YncE-family-protein	unknown	unknown	gnl|CDD|225926
NC_021658.1|WP_020738054.1|8728569_8729316_-|c-type-cytochrome	unknown	unknown	gnl|CDD|225797
NC_021658.1|WP_049949679.1|8725619_8726429_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|225136
NC_021658.1|WP_148314017.1|8730816_8732421_+|metallophosphoesterase	unknown	unknown	gnl|CDD|213859

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020738046.1|8718453_8718813_+|phage-holin-family-protein	gnl|CDD|377198	pfam04020, Phage_holin_4_2, Mycobacterial 4 TMS phage holin, superfamily IV. These proteins are predicted transmembrane proteins with probably four transmembrane spans. The 1.E.40 is represented by the mycobacterial 4 phage holin, but it also contains many cyanobacterial. proteobacterial and firmicute proteins. Holins are encoded within the genomes of Gram-positive and Gram-negative bacteria as well as in those of the bacteriophage of these organisms. The primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded the enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some may catalyze export of nucleases.	5.28382e-10
NC_021658.1|WP_044986293.1|8718906_8719890_-|aldo/keto-reductase	gnl|CDD|381312	cd19086, AKR_AKR11C1, AKR11C family of aldo-keto reductase (AKR). Bacillus subtilis uncharacterized oxidoreductase YqkF is a founding member of aldo-keto reductase family 11 member C1 (AKR11C1). It may function as oxidoreductase. This family also includes Bacillus halodurans AKR11C1, an NADPH-dependent 4-hydroxy-2,3-trans-nonenal reductase.	5.52957e-112
NC_021658.1|WP_148314014.1|8719955_8721740_-|DNA-mismatch-repair-protein	gnl|CDD|213210	cd03243, ABC_MutS_homologs, ATP-binding cassette domain of MutS homologs. The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family also possess a conserved ATPase activity that belongs to the ATP binding cassette (ABC) superfamily. MutS homologs (MSH) have been identified in most prokaryotic and all eukaryotic organisms examined. Prokaryotes have two homologs (MutS1 and MutS2), whereas seven MSH proteins (MSH1 to MSH7) have been identified in eukaryotes. The homodimer MutS1 and heterodimers MSH2-MSH3 and MSH2-MSH6 are primarily involved in mitotic mismatch repair, whereas MSH4-MSH5 is involved in resolution of Holliday junctions during meiosis. All members of the MutS family contain the highly conserved Walker A/B ATPase domain, and many share a common mechanism of action. MutS1, MSH2-MSH3, MSH2-MSH6, and MSH4-MSH5 dimerize to form sliding clamps, and recognition of specific DNA structures or lesions results in ADP/ATP exchange.	2.34373e-36
NC_021658.1|WP_148314013.1|8713364_8715533_+|anthranilate-synthase-component-I	gnl|CDD|237429	PRK13566, PRK13566, anthranilate synthase component I.	0
NC_021658.1|WP_049949678.1|8723099_8724668_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.934e-72
NC_021658.1|WP_020738058.1|8734267_8738875_+|glutamate-synthase-large-subunit	gnl|CDD|236968	PRK11750, gltB, glutamate synthase subunit alpha; Provisional.	0
NC_021658.1|WP_020738038.1|8707378_8708230_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	2.30141e-87
NC_021658.1|WP_020738039.1|8708267_8709200_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.38073e-89
NC_021658.1|WP_044986292.1|8716847_8718200_+|argininosuccinate-synthase	gnl|CDD|235434	PRK05370, PRK05370, argininosuccinate synthase; Validated.	0
NC_021658.1|WP_148314016.1|8726600_8727662_-|3-oxoacyl-ACP-synthase	gnl|CDD|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	6.10785e-125
NC_021658.1|WP_020738053.1|8727934_8728561_-|endonuclease-III	gnl|CDD|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	1.06916e-89
NC_021658.1|WP_044986296.1|8733189_8734035_-|metallophosphoesterase	gnl|CDD|224327	COG1409, Icc, Predicted phosphohydrolases [General function prediction only].	1.03579e-17
NC_021658.1|WP_020738054.1|8728569_8729316_-|c-type-cytochrome	gnl|CDD|225797	COG3258, COG3258, Cytochrome c [Energy production and conversion].	8.62354e-06
NC_021658.1|WP_020738042.1|8711899_8713180_+|isochorismate-synthase	gnl|CDD|224091	COG1169, MenF, Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	6.45498e-104
NC_021658.1|WP_044988940.1|8709322_8710552_-|extracellular-solute-binding-protein	gnl|CDD|270453	cd14750, PBP2_TMBP, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose; possesses type 2 periplasmic binding fold. This group represents the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.05741e-137
NC_021658.1|WP_020738057.1|8732451_8733189_-|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl|CDD|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	8.68371e-33
NC_021658.1|WP_044986295.1|8729312_8730548_-|YncE-family-protein	gnl|CDD|225926	COG3391, COG3391, Uncharacterized conserved protein [Function unknown].	1.10064e-08
NC_021658.1|WP_049949679.1|8725619_8726429_-|methyltransferase-domain-containing-protein	gnl|CDD|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	6.61808e-23
NC_021658.1|WP_148314017.1|8730816_8732421_+|metallophosphoesterase	gnl|CDD|213859	TIGR03767, P_acnes_RR, metallophosphoesterase, PPA1498 family. This model describes a small collection of probable metallophosphoresterases, related to pfam00149 but with long inserts separating some of the shared motifs such that the homology is apparent only through multiple sequence alignment. Members of this protein family, in general, have a Sec-independent TAT (twin-arginine translocation) signal sequence, N-terminal to the region represented by this model. Members include YP_056203.1 from Propionibacterium acnes KPA171202.	4.32421e-46

Protein sequences

>NC_021658.1|WP_148314014.1|8719955_8721740_-|DNA-mismatch-repair-protein
MPRPSLATAERRRRTPDERSGPTHRRLEIVSAAPPEPVLPDASPGQRAAPDLLCHRPALRVDARAVKESMTFAFAGGAPAGALDRHVESASLPASTWDPARFAQHVFLQELIVGCLHFTSEGRTRIPSPALLGRALSQPPSDRDTVELRREIFRELTGSEALRRDLARAYAALRRWVSQLETISISRREGSRRRLDILVAAKEAFDALADGFAGARSGLARLPAFGAAVRETEAYRRLADLLAYDEELATLEVRIRVGADGHVRDLRALSIRENSENRFYQSPIGRVVTKLVMLWRGYRFSDEELLARYVNGVFDGIEDDLVALVQLLGDLEFYLAGLALRERARAAGLAVCLPELAWPGAARDEAPGRALKGLFNPLLLATSASIVACDIATEHHDATVIVTGPNSGGKTRLLEALSLAQMLGQAGFFVPAAEARLSSCHGLFVSLIEQAQADQSEGRLGMELLRIRSLFEAMQVGDMVVLDELCSGTNPSEGEEIFQLVISLLAELRPQAFITTHFLELAARLERERPVDRLVFLQVELDAQQWPTYQFVDGVARTSLAHRTAARLGVTREELVALVERSKRAHRRRGVEPA
>NC_021658.1|WP_044986293.1|8718906_8719890_-|aldo/keto-reductase
MEYRPLGRTGLRISSVSFGAWAIGGTWGDVDDKESVAALHRAVDRGVNFFDTADVYGDGRSERLLARLRRERREEIVIATKAGRRLSPHTADSYSEGNLTAFIERSLKNLETDALDLVQLHCPPTDVYYRPEVFDVLDRLVKAGKVRFYGVSVERVEEALKAIEYPGVQSVQIIYNVLRQRPAELFFPEAKRRQVGILARLPLSSGLLTGKMSAATTFAADDHRNFNREGAAFDKGETFSGVDFDLGLEVVEELRPLVPAGVSMGAWTMRWILMQDAVTCVIPGAKRPDQVDQNASAADLPALPPETMAKIRAIYDRRLRAAVHHRW
>NC_021658.1|WP_020738046.1|8718453_8718813_+|phage-holin-family-protein
MKTLIIQAIAAGIAVLIGAKLMPGVRIRRTQTALVVAAVFTLLNLLLGWLVKFLVAVALLPAAILTLGLAYLFFGLVVNSVLLWATDKLIDDFEIRGLGSLFGTAALVSFAGWLLPRIL
>NC_021658.1|WP_044986292.1|8716847_8718200_+|argininosuccinate-synthase
MSRIFRSLPPAGTHLGIAFSGGLDTRCAVAWLSRNGLKVHAYTADLAQPDEDSPGDIPPIALQHGAVSAKLVDCRDALVHEGILAIQCGAFHLSTGGKKYFNTTPLGRAVTTTAIVRAMRDDDVHVFGDGSTHKGNDIQRFYRYGIFVDPSLKIYKPWLDPKFVGELGGRKEMSEYLERHSLPYRMGTEKAYSTDANVLGATHEAKDLEHLNTGIKIVQPIMGVASFRPEVAIEAETVTLGFERGVPTTIDGKRYGSLFELFVECNRIGGRHGLGMSDQIENRVIDAKSRGIYEAPGMALLHAVYERLLSAIHNENTLDVYFTQGRRLGRLLYEGKWYDPEAMMLKDALSRWIAPGVTGEVTLELRRGDDYSILNTRADYMAYAPHKLSMEKVEEAYFTPEDRIGALELQNLSVTDNRQLLIHLIESTQALGPGGAPAIGELLGGDKPKE
>NC_021658.1|WP_020738044.1|8715858_8716686_-|hypothetical-protein
MPKLSYVEIARIEERRLALGTSSVVACAEPIAGGWMAFDGDGSWGNFAAGLGLDGPVSSEDLDRLVAFYAARDMEPQIQVCPFAHESLVRGLAERGFALREFENVLAREIAPDEDLRALAPHGGPAGLEIVRVDPGDEAQVRAFIEVSTSGFRVEDEPLTPALFEITRRVVAQPGCDSYLALVNGEPAGGGSVEIAGDGAALFGASVLPRFRERGIQQLLIVRRLERVRERGRRLACISASPGIPTERNALRLGFFMAYSKGVFVQRKGNQRLPT
>NC_021658.1|WP_148314013.1|8713364_8715533_+|anthranilate-synthase-component-I
MKRESNITRRGVAVRREVEDLAVDGAIQPVVEALDTHLGVVLASSYEVPGRYTRWDIGFVDPPLVLVSRGRDFRFTTLNERGRVLLPAIEEALRGYEPIEAVERRPDEVVGAVRPAGERVPEELRSRQPSIFSVLRRMIELFGVPGDPLFGLYGAFAYDLAFQFEPIRLRLERPADQRDLVLYLPDEIVAVDHRRERATRTRYELKFGDRSTEGLPRDGATRPYVGAHSAPPNEYAPGEYAALVRVARESFKRGDLFEVVPGQTFYEPCPVAPTELFQRLRERNPAPYGFLMNLGEAEYLVGASPEMYVRVEGNRIETCPISGTIPRGSDPIADAAQIARLLASAKDESELTMCTDVDRNDKSRICVPGSVRVIGRRQIEMYSRLIHTVDHVEGRLRDGFDGLDAFLAHTWAVTVTGAPKAWAMQFIEDHERSPRAWYGAAVGLIGFDGSMNTGLTLRTIRIKDGVAQIRAGATLLYDSDPDEEERETHVKASALIDAIRRPRGVPTTAPAAINPVPGGGLKVLLVDHQDSFVHTLANYLRQTGAEVVTLRAGFPHKELDAYAPDLVVLSPGPGTPSDFDLSGTLSALLERRLPVFGVCLGLQGMVEHFGGKLGVLDYPMHGKASKVRVLGGRIFEGLPREFHAGRYHSLHALRDALPASLKITAETEDGVVMAIEHAELPMAAVQFHPESILSQDDDVGLRLVRNAVAELRRGARGEAVKR
>NC_021658.1|WP_020738042.1|8711899_8713180_+|isochorismate-synthase
MTPLTLSSPPDAPRLAARLVARTVRLDADTLARMPGGISSLAGDGARVWMHPSAQLIAHGVAARLELPHGIEGGVAWIQEALSSIAASDAVGRPGCGPVALGALPFDRTEPAALVVPAQVVGVAPDGTAWVTTVGEGAAPAPHLERAESHRRSPDSFTLKSALPHEEWCGRIARAVADIQHGDLSKVVVARAVDVEANRPIVVEEVLRRLTALYPSCAIFHVDGFLGASPELLLSRRGRAVSSHPLAGTYAVSADVDADRRFSEVLRKSAKDQREHRFVVEAVAAALAPECASLDVPSEPSILSLRNVMHLGTPVHGHLKEAAPDALTLAARLHPTPAVCGTPRAAAEAWLSAHEGIRRGLYAGLVGWVDARGDGDWFIGIRSATVDGARARMVAGVGVVAGSSPEAELVETQLKLQAMLAAIIRP
>NC_021658.1|WP_044988940.1|8709322_8710552_-|extracellular-solute-binding-protein
MKAQPPTVPNAAEAKKHAGSKLKYYSEPLGVGAELDKVMVKQFQQDTGIEVTIIPRPKDATETYAVYQRLFQAQSGDVDVMMLDVIWPGAFAQNLVDLNEKLGEAAKQHIESIVRNNTVGGKLVAMPWFTDFGLLYYRTDLLGKYGYEKPPETWDELEQMAKKIQDGERASNPNFLGFVWQGKAYEGLTCNALEWIASHGGGAIIEDGKITVNNPGAQKALARAKGWVGSISSAGVTSYEEEDARNTFQGGNAAFMRNWPYAYAAGNADKSPIKGKFGAGPLPHEPGQKSSGTVGGWQLAVSKFSPNKDAAIEFVRYMTSPEAQKFRATAGSFIPTIPSVQQDPDVVKSLPFLANAKDIALVPRPSNSTGARYNEASIAFFQGVSQVLQGKEPKAVLGQVEQRLTRALR
>NC_021658.1|WP_020738039.1|8708267_8709200_-|sugar-ABC-transporter-permease
MSTPENREATSAAPRADSASFERRRQRRAWLFLLPTLVVVAFVALYPLAQTFYLSFTNARLGTGEPATLVGAQNYVDLVQDSYFHDAVLLTVLFTVVTVLSELALGLGIALLVNSQFKGRSAVRAAMLIPWAIPTVISAQMWKWMYNDVYGVFNDLLVNRLGVLPRNVAFVADPDVSFWAVAIIDIWKTTPFMALLLLAGLQLIPSDLYEAARVDGATPLQQFTRITLPLLKPSMLVALIFRTLDALRVFDVFFVMFGNRPDMQTMATYAQQTLVSVSNIGYGSAISVALFLIIAVFILIYLAVFRTEEA
>NC_021658.1|WP_020738038.1|8707378_8708230_-|carbohydrate-ABC-transporter-permease
MQRSPAQRTLRALFYLLVAAVVVFTVFPFVWAFVSSIKPDDELFTTPVRYWPGRPTLENYRLVLDNGEFQTALLNSVIVAVSVTALSLAVGSLAAYALGRFRFRGRSAVLYVVLAMTIFPQIAVLGALFEMINFFKLYNQLPALVLTYLIFTLPFTVWVLTGFLKAIPREIEEAAYVDGATPWQVFTRIMLPLSVPGMATTGILAFIAAWNEFLFALSFTQTPDKRTVTYAIQAFSTTTSGLYEIPWGQTMAASIVVTVPLVVLTLVFQRRILAGLTAGAVKG
>NC_021658.1|WP_049949678.1|8723099_8724668_-|serine/threonine-protein-kinase
MADVFLAMAHGPASVNKLVVVKRLRSFADEEDRQVLMFMDEAKLSARMNHLNVVQTYEVGSDQEGYFIVMEYLEGQPLKRVMKAAMDRASGTGGLVRGTWIRIVAEVLRGLHYAHELCDFDGKPLGIVHRDVSPHNIFITYDGAVKLVDFGVAKAAVNSSNTESGTFKGKLTYMAPEQVTAGKTVDRRADIFAVGVVFWELLAGRRLFEGDQITVMHQLLLGKIPRLSTVVPGIPIALDQIAAKALERDPSKRFATAQEMCDVLESYLQWSGEDVRGEFLGACMRGIFAESRASIRQQIKAQIERVTSSMMMSEGSGQVTLSGIGLSAGPTSSRSGSRLPFVGEPSNSGVERGSGVERGSGVERAGLGCRAGLGCRAGLGRRAGLGRRAGLGRRAAQDPGERLGQPARDHVGALDALEARLPARSLRARRAGRGGRGRAARREQARARGRASGGRRRCARRGGRGGRREEAGGGPQGERGDRERPARRHGELEGDDARQDAAQDRAARGHAGRGRVAVRQLR
>NC_021658.1|WP_049949679.1|8725619_8726429_-|methyltransferase-domain-containing-protein
MHSANQLVRSVYDRIAERYDDQWGRHMREPQDRLTAGLGLAPGARCADLGCGTGIETVEMLRRVAPGEVVGVDCSEEMLRAARARARAAGLALSTMRAEAELFIRRAEASSFDVVTLRFCLAYLDWRSALPCLGRMVRPGGRAGILTNLSSSTPQAYAVYCRMVDELNLGRVELPVPDSPGQVSEALQRGGLRAVEAWTHRFRLWFGSGAQVASWLQESGFVTHAALREFPPEVLQPLCDEFAARLEAYREPDGIPLDFELAGVIAARR
>NC_021658.1|WP_148314016.1|8726600_8727662_-|3-oxoacyl-ACP-synthase
MAKMGFEIIGTGHYVPGEPVTNDDLARVITTSDEWVYQRSGIHQRHYAPDGVGVSDLACEAAKRAIESARISPSEIDYILFATMTPDYIFPGSGALLGAKLGIPGVPALDIRQQCAAMLFGLQTIDGLIQTGAAKTILFVGAEAHAGFMPWEDWGALDPKNGRSATPEARARADRHRNLAVLFGDGSGALVLRATDRDAGLRGNKICSDGRFAELLYVPGGGFRSRPYWKQSSFEDDAHIPRMDGRELFKFAVTKLPATARELCASQGVTIEQIDVFLAHQANGRINEHIRKDLGVPVEKLPSNIDRFGNTSGATVPILIDEEMRAGRVKKGQLAMVLALGTGVHWGCALWKL
>NC_021658.1|WP_020738053.1|8727934_8728561_-|endonuclease-III
MKRPEKAARIAEILDRLYPQPAIPLVHEDPYSLLVAVMLSAQTTDKMVNAVMPALLARARTPAEMAAVPTEEIAELIRRIGFAPTKARHLKALSERIAVEHGGVVPASFEALEALPGVGHKTASVVMAQAFGHPAFPVDTHIHRLASRWGLSSGKNVVETERDLKRTFPPERWNKLHLQLIYFGREHCPALRHDTAGCPICSWAARRR
>NC_021658.1|WP_020738054.1|8728569_8729316_-|c-type-cytochrome
MRPRALALAALAGAALASGCTGDPETKIVDATAVEHGAALFRDPSVAETRFNRYSCSTCHEAIAGEAGDAMLPGAPLAGAVDRPYYWGGQEVDLLGAINHCLYYFMTKDLPWAADDPAAQAMYAYLESLPSDGDAAEAVPFTPVYGLREPPPGDPGRGALIHDRACASCHGRARSGEGRLVERAPALPDQTLEEHPLGEYTERERRLVFVEKVRHGGFIGYGGQMPPFSLEVLSDEQFGDLLSFYALP
>NC_021658.1|WP_044986295.1|8729312_8730548_-|YncE-family-protein
MVLSRFVGFVLAAVALAGCGEPDPIIETHYGAYEGDAYPDRRPKITVPEGGMGVVSDSRSDTLSLISLATGERFGVYPVGRDPVTVDGPHHVAVDAPGNAVYVALSYPVLAGTIGPHASHGSSAMAGYVQKLALDDMRVLGQVRIEPNPGDIVISEDGGRVVASHYDLKRAIDNPQDIEAARSSLAVIDPDEISRSGSAQPVLIPTCIAAHGIALSRPDGARAYVACEGEDALAVVDLTDPGAEVKRVPVGPSPAVWVPSYAPYAAVMSPDQKTIAVSNTRSRDVRFFDVASESFREPHSIVTLQGAPYFVAWTADGSRLYVPTQAPDAIALIDVANGNAELAYRDLSGDCEKPHVVDYDGGDGLFLVCEGDQTETPGKVLRLDPETLETRSEADVGLFPDAFVRVAAEAP
>NC_021658.1|WP_148314017.1|8730816_8732421_+|metallophosphoesterase
MSQTRAGSTMTAELVRSLGARVRRGGPAAVLCLALVAACAAEESVGPTPAPTPLPALADAPPLTTERTLVPRAAVVDPPDRNPAVPAKIEQMLAEGYGELEIGPGLPLAPATLDGAPPPPRGPRPRLLTRFVHLADTQLADDESPARLAIFDSPAIGSAFRPQEGHECRILNAAVRTINAFHRSTPLDFVLLGGDNADSAQTNEIAWFTAILDGAERVECDSGDDDDPVQGPDNDPKDPFVAEGLLVPWRWVTGNHDVLHQGNFPVDTRAAIATGNIADGGTRSWALPGGPVITGEVVPDPRRALLSRPALLDHLAAAGDGHGIGPDEQAYGKAFYEFDVKDTPVRVVVLDTAAETGGPGGVILQDDVDRFIRPALDRARLDRRWVVLASHHASRLLGDGSFAATGTPAVPGALTVEAWQSLVGGYDNVLLHLAGHTHVHRVTPVTPSGGHAYWELETSALADYPHQVRVIEIWDEDNGSVAIRGVALDYAVDGDAVAAEGRRRAVVDVTSGFGSDGSGEPSWRNVELSIARPD
>NC_021658.1|WP_020738057.1|8732451_8733189_-|4'-phosphopantetheinyl-transferase-superfamily-protein
MLEIGPGIAHLWYVFCEPIRDEALLAAYHRLMAPDEAAQQARFLFAENRHEYLLTRALVRTTLSKYADVAPEAWTFVRNEFGRPQIAGPPGVPPLRFNLSNTRGLIACLVALDRDVGVDVEDTERSSSAVDIADRFFSPAEVRALRALPPERQRARFFEYWTLKESYIKARGMGLAIPLDQFSFHLDDGPSIGVSFDPRLADDRSAWQFALYQPSARHTMAAAIRTGGAPPLSIELRETVPLRDG
>NC_021658.1|WP_044986296.1|8733189_8734035_-|metallophosphoesterase
MKLFALSDLHVGYAENRWALERVTPRPNDWLILAGDLGETEQHLLYVLDTLGPRFKQLVWAPGNHELYTMPSERGGPRGQARYDRLVELCRSRGVITPEDPYVLWEGEGGPHVLAPMFLLYDYSFRPADVAELDAVAWAMESGVLCSDEELLDPAPYASRPEWCRARLAETEARLAAIEAHATVLINHFPLREELVRLRHIPRFSIWCGTRRTHDWHTRFRARVVVSGHLHIPRTDWIDGVRFEEVSFGYPRQRPIGLTADSCLREILPGPAAAAPLPGTA
>NC_021658.1|WP_020738058.1|8734267_8738875_+|glutamate-synthase-large-subunit
MPLPQRQGLYDPAFEHDACGLGFVATLRREATHEVVCQALEILENLTHRGAAGCDPCTGDGAGILLQIPHELYAASLASLGIALPPPGDYAVATAFFSQSPSRRRQCEAILEAAVVHHGQRVLGWRDVPIDDGAIGPVARDSRPAIRQLFIGRVASRQSFEQVLYAIRKRAGRTAHSDDFYLASCSSRTVVYKGLMLAEQVAAFYPDLSDKRTVSRLAMVHSRFSTNTFPTWERAHPYRVIAHNGEINTLRGNTAWMSAREALLKSDVFASAIEDFKPIIRAGGSDSAALDNVVDFLLASGRSLPHVMMMLVPEAWALDPDMSAEKKAFYEYHGCLIEPWDGPAALCFTDGRLIGATLDRNGLRPAKYVVTSDGLVVLASEFGVLDIEPARVIQKGRLQPGKMFLVDTSEGRVVSDDEIKRRVATQKPYAAWVAENKIDLRALEDVPSLYTIPHSDLRTLQQAFGYTDEDQRMILASMATLGEEPVGSMGIDIPLAVLSEKPQLLFRYFKQLFAQVTNPPVDPLREEIVMSLVSCVGGEGNLLEETPRQCRMLELPHPILTQDDLSKLRKNVFPDFRAATLPMYFSVDGDPEDNLRSALAKLCKDASRAIADGASILILSDRGIDETLAPIPSLLAMGAVHHHLINEGTRTRAGIIVETGEAREVGHMALLIGYGAGAVNPYLAFESIAAMCRDKTLGPDLSPSAASSRYVKALKKGILKIMSKMGISALSSYQGAQIFEAIGIDQIVIDAYFTGTASRVRGVGLREIAEEALARHQAAYGERARAHLDVGGHHHFRVFGERHLWTPQSISSLQRAVRLDDAKSYAEYAATINEQQEHPMSLRGLWDLRPAGPPVPIEEVEPAASLVKRFATGAMSFGSISKEAHETLAVAMNRIGARSNTGEGGEDPARFIRLSNGDSKRSSVKQVASGRFGVTAEYLVNADELQIKMAQGAKPGEGGQLPGHKVDAVIAKVRHSTPGVTLISPPPHHDIYSIEDLAQLIFDLKNINSKARISVKLVAEAGVGTIAAGVVKAHADVVLISGDSGGTGASPLTSIHHAGVPWELGLAEAHQVLVMNGLRGRAIVQTDGKLMTGRDVAFAALLGAEEFGFSTAPLVATGCIMMRKCHLNTCPVGIATQDPELRKKFTGAPEHVINFFFYVAEELRQIMASLGFRTLTEMVGRSDCIVQRRTGLHAKARKIDCSEVLYRPKEALTSPNHCVEPQDHKLDRVLDLKLIEQARAAIDGGPPVVIETRVRNSDRTIGAMLSGEIARRHGSAGLPEDSIVVKCAGSAGQSFGAFASQGMTLELEGDANDYVGKGLSGGVVAVRPPSVAPFKPDDQVIVGNVVLYGATSGRAFFNGRAGERFAVRNSGATTVVEGVGDHGCEYMTGGTVIILGTTGRNFGAGMSGGLAYVFDEDALFEARCNKEMVQLETMTAADAESVRALLEEHVRRTGSRKATELLDSWQAVLPKFVKVVPSEYRRALEAAASPATNGADASSGIVSLLSPSTPYVSTGRYIPANAGPASTGERSAAHG

Crispr_ID: NC_021658_33

• CRISPR_ID: NC_021658_33
• CRISPR_location: 8825266-8825396
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_021658_33

Consensus_repeat	Method
AGCGCTCGGCCCGGTCGGAGCGC	CRISPRCasFinder

spacers of NC_021658_33

>33.1|8825289|31|NC_021658|CRISPRCasFinder
TCGACGCGCTCGACGCGCTCCACGCGGTCGA
>33.2|8825343|31|NC_021658|CRISPRCasFinder
TCGGTCCGGTCGGTCCGGTCGGTCCGGTCGG

CRISPR arrays and Neighbor proteins around NC_021658_33

CRISPR arrays

The CRISPR arrays of NC_021658_33

>merge|NC_021658|33|8825266-8825396|CRISPRCasFinder
AGCCCTCGGCGCGCTCGACGCGCTCGACGCGCTCGACGCGCTCCACGCGGTCGAAGCGCTCGGCCCGGTCGGAGCGCTCGGTCCGGTCGGTCCGGTCGGTCCGGTCGGAGCGCTCGGTCCGGTCGGAGCGC

>NC_021658|33|29|8825266-8825396|CRISPRCasFinder
AGCCCTCGGCGCGCTCGACGCGC	TCGACGCGCTCGACGCGCTCCACGCGGTCGA
AGCGCTCGGCCCGGTCGGAGCGC	TCGGTCCGGTCGGTCCGGTCGGTCCGGTCGG
AGCGCTCGGTCCGGTCGGAGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_148314911.1|8830445_8831285_-|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|379311
NC_021658.1|WP_044988948.1|8836505_8837297_+|OmpA-family-protein	unknown	unknown	gnl|CDD|224279
NC_021658.1|WP_020738117.1|8819845_8820850_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738115.1|8817869_8818841_-|DNA-processing-protein-DprA	unknown	unknown	gnl|CDD|376794
NC_021658.1|WP_044986311.1|8811930_8813415_-|DUF2330-domain-containing-protein	unknown	unknown	gnl|CDD|370813
NC_021658.1|WP_020738119.1|8821734_8823231_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020738129.1|8839450_8840014_-|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|224511
NC_021658.1|WP_044988946.1|8827503_8830254_-|alanine--tRNA-ligase	unknown	unknown	gnl|CDD|234701
NC_021658.1|WP_020738120.1|8823394_8824282_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738125.1|8831571_8833794_-|TIGR04551-family-protein	unknown	unknown	gnl|CDD|275344
NC_021658.1|WP_020738128.1|8837836_8839387_+|hypothetical-protein	unknown	unknown	gnl|CDD|379062
NC_021658.1|WP_148314023.1|8818917_8819766_-|hypothetical-protein	unknown	unknown	gnl|CDD|237865
NC_021658.1|WP_020738122.1|8827029_8827422_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080682373.1|8834231_8836367_+|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NC_021658.1|WP_044988950.1|8840184_8840799_+|isoprenylcysteine-carboxylmethyltransferase-family-protein	unknown	unknown	gnl|CDD|224931
NC_021658.1|WP_020738118.1|8820846_8821650_+|hypothetical-protein	unknown	unknown	gnl|CDD|176506
NC_021658.1|WP_080682767.1|8815142_8817740_-|type-I-DNA-topoisomerase	unknown	unknown	gnl|CDD|235840
NC_021658.1|WP_148314024.1|8843309_8844119_+|hypothetical-protein	unknown	unknown	gnl|CDD|376164
NC_021658.1|WP_020738107.1|8811706_8811922_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738109.1|8813693_8815136_-|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	unknown	unknown	gnl|CDD|235416

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_148314911.1|8830445_8831285_-|HEAT-repeat-domain-containing-protein	gnl|CDD|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	4.84746e-11
NC_021658.1|WP_044988948.1|8836505_8837297_+|OmpA-family-protein	gnl|CDD|224279	COG1360, MotB, Flagellar motor protein [Cell motility and secretion].	6.84454e-31
NC_021658.1|WP_020738129.1|8839450_8840014_-|RNA-polymerase-sigma-factor	gnl|CDD|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	1.23569e-16
NC_021658.1|WP_020738115.1|8817869_8818841_-|DNA-processing-protein-DprA	gnl|CDD|376794	pfam02481, DNA_processg_A, DNA recombination-mediator protein A. The SMF family, of DNA processing chain A, dprA, are a group of bacterial proteins. In H. pylori, dprA is required for natural chromosomal and plasmid transformation. It has now been shown that DprA is found to bind cooperatively to single-stranded DNA (ssDNA) and to interact with RecA. In the process, DprA-RecA-ssDNA filaments are produced and these filaments catalyze the homology-dependent formation of joint molecules. While the E.coli SSB protein limits access of RecA to ssDNA, DprA alleviates this barrier. It is proposed that DprA is a new member of the recombination-mediator protein family, dedicated to natural bacterial transformation.	1.21829e-59
NC_021658.1|WP_044986311.1|8811930_8813415_-|DUF2330-domain-containing-protein	gnl|CDD|370813	pfam10092, DUF2330, Uncharacterized protein conserved in bacteria (DUF2330). Members of this family of hypothetical bacterial proteins have no known function.	1.31136e-36
NC_021658.1|WP_020738119.1|8821734_8823231_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.27407e-99
NC_021658.1|WP_044988946.1|8827503_8830254_-|alanine--tRNA-ligase	gnl|CDD|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NC_021658.1|WP_080682373.1|8834231_8836367_+|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	1.84601e-37
NC_021658.1|WP_020738128.1|8837836_8839387_+|hypothetical-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.00484364
NC_021658.1|WP_148314023.1|8818917_8819766_-|hypothetical-protein	gnl|CDD|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	9.06175e-05
NC_021658.1|WP_044988950.1|8840184_8840799_+|isoprenylcysteine-carboxylmethyltransferase-family-protein	gnl|CDD|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	1.93684e-24
NC_021658.1|WP_020738118.1|8820846_8821650_+|hypothetical-protein	gnl|CDD|176506	cd08563, GDPD_TtGDE_like, Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in Thermoanaerobacter tengcongensis glycerophosphodiester phosphodiesterase (TtGDE, EC 3.1.4.46) and its uncharacterized homologs. Members in this family show high sequence similarity to Escherichia coli GP-GDE, which catalyzes the degradation of glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols. Despite the fact that most of GDPD family members exist as the monomer, TtGDE can function as a dimeric unit. Its catalytic mechanism is based on the general base-acid catalysis, which is similar to that of phosphoinositide-specific phospholipases C (PI-PLCs, EC 3.1.4.11). A divalent metal cation is required for the enzyme activity of TtGDE.	5.33158e-53
NC_021658.1|WP_080682767.1|8815142_8817740_-|type-I-DNA-topoisomerase	gnl|CDD|235840	PRK06599, PRK06599, DNA topoisomerase I; Validated.	0
NC_021658.1|WP_148314024.1|8843309_8844119_+|hypothetical-protein	gnl|CDD|376164	pfam18742, DpnII-MboI, REase_DpnII-MboI. REase Fold fused to DpnII/MboI-NTD.	2.50586e-08
NC_021658.1|WP_020738125.1|8831571_8833794_-|TIGR04551-family-protein	gnl|CDD|275344	TIGR04551, hypothetical_protein_CAP_1272, TIGR04551 family protein. Members of this family are proteins of unknown function, about 620 amino acids in length, and universal in but restricted to the Myxococcales, an order within the Deltaproteobacteria with at least 15 sequenced genomes as of 8/2014. The most closely related homologs outside the Myxococcales show localized homology only and display sharply lower scores. Relatively few protein families (roughly 20) could be built to have a comparable restriction to the Myxococcales. The putative protein sorting signal MYXO-CTERM (TIGR03901) appears so far universal in but restricted to the Myxococcales, making the present family a candidate to be involved in recognizing and processing proteins with that signal.	0
NC_021658.1|WP_020738109.1|8813693_8815136_-|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	gnl|CDD|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0

Protein sequences

>NC_021658.1|WP_020738120.1|8823394_8824282_-|hypothetical-protein
MRHRAIAWAAPLAVLVTGCAAVDPPPSRFPTADAALGRMKDTYACVNGVQGTAKIDHFSRQGRIRGDVYILAVNPDRVRFDVVSPFGATLYTLTSNGTLFQMLDVGEKQLLHGPASACNLARLTQVPIPGHALVSLLRGEAPVLAHEPHGASIAWDGDGFYRVLIQSTRDAVEEIHLEPRPDDWRLPWSQQRLRVRQVRVAQRGMDLYHAELSNHGVIRTAPPRVDPEGIDDPIPPSGGACEAEVPRSIRMRVPNTEDDVIFQYKEAKWNPPLLSGAFTQPIPGGVVRRYVDCQD
>NC_021658.1|WP_020738119.1|8821734_8823231_-|serine/threonine-protein-kinase
MDVEPGTIVGEKYRLEKPLSRGGMGSVWAARHVQLGAPVAIKFMDPEHAAAPEFRARFYREARTAANLESPHVVSVQDYGIQGSVPYLVMELLRGEDLSRRLRRVRRIPLADAARVAVQTGKALRRAHESGLVHRDLKPGNLFLARVDDDEEIVKVLDFGIAKQLAGKLLSGETTKTGELLGSPFYMSPEQARGDKDLDARSDLWSLGVILFRAVTGKLPFEGDVLGAVLSRILVEPIPLATQVASDLPAELDGFFLRALSRERSQRFQSAQEMVHAFVAAAGDLGIPLAAPSVPRPPPAASRTGTLLGLSPAGAAELSGPGDVGALSWSEAPEDQGAAPREDALTPLPDPSQPGTLTAAAAGEVRDARRPRASATRRWLLACGALFVLSGTAALTALRPVGPEGAGAVVAPVEPAPVEPAPAITAPPVEVARASAPVADRLIVPESAPAVDAAPPSPAPSGTAEPAASAARKDPPARAAPRRAPHRAREIVDPWQRR
>NC_021658.1|WP_020738118.1|8820846_8821650_+|hypothetical-protein
MTWAEQRFRRSARAAGLVAPRGEDGALGPCAPLLFGHRGVRGEGAPAENTLAAFEEAAAQGADGIELDVRVCGSGELVALHDPELERVTQGADPRAAAALRWDELRQVDLGGERVPLVSEVLAFARGRRLAVNIEMKRDVPDRAAVVLATARLLRAWDPRHAVLVSSFDPVMLASFGVMAPAVPRALLVHRSRYHDTAVRLAPALGALAAHIERTIASPERIALLKRQGRVINVWTVNDPREARDLAALGVDGLITDVPRRLREALA
>NC_021658.1|WP_020738117.1|8819845_8820850_+|hypothetical-protein
MKPRDIVVATHGHCFDGMASAALFTRLMQALRPGEPLALRYRSCGYGPGMTMIPPSWLDGDENAILDFRYTPTKKLTWYFDHHITGFGSDDERDAALAGASRGGAVGDAPHVFYDAAYGSCTKLIADVGRDHFGVEMSGVDELIRWADLIDTARFPSAEAAVSREEPIMQLASVVEHHGDGPFLASVVPRLVERPVSEVARAPDIQELWRPLSLSRQTFVARIERGARKLGRVVLVDLSDAPLEAVGKFMTYAMYPDCVYSVTLSRQKQHYKLSVGYNPWCGVPRDRDIAPICRRYDGGGHPAVGAASFPLSALERAREAARTIAEELNEEPAR
>NC_021658.1|WP_148314023.1|8818917_8819766_-|hypothetical-protein
MRRALVPLALHPFRPARRLAGAPLAALLVALLAASGCGGGSAPRAEVLQPSPPPAPAPAPTREVRNPPPPSDAPEPDPEAARLFLSRVGQQRPAASAPAPRVTALALANTARGEARGMTPLGDVVSLAIGEGESSAIPVRVAPGECAVFIAQGGLGVIEVDLFVTKGAPPSHEIVGQDADSGPIAVIGGRGACFTSPGGAPFAGSLHAQVRRGAGVVLVQGYRGPRLPAPRGAGPPGATPPDTAPPSAAPPSAAPPSAPSFSAAPSSSAAPPGAASLRAPPR
>NC_021658.1|WP_020738115.1|8817869_8818841_-|DNA-processing-protein-DprA
MASIEIQPADPSYPAPLWALVTETEAAPPTLYLRGALPSRPGIAIVGTRAASDDALRFTRALAASLGEAGYSIWSGGARGVDAAAHEGALAARAPTVVVSGGGHARPYPREHAPLFDRIVAAGGALLARVPDDTPPLPGLFLQRNAVLAALTLATVVVEAGIESGARSAAAAARRLGRHLCVVPHAPWSPRGVGCALELVAGARPVTRAADVIDVLGGPAPPPRRRARRSPRNSPPAAGTLPLPDPAVAAPTSAPPEETAQIPAMSAVERAVFDALDACPAHVDEVCERTGLPPRRAVEALLTLTLQAVVVEGPAGLFRRALR
>NC_021658.1|WP_080682767.1|8815142_8817740_-|type-I-DNA-topoisomerase
MAKTLVIVESPAKAKTIKKYLGNGYEVFASKGHVKDLPKKQNAVDVQNDFAETYEVIEGKEKVLEELKSAAKKADEVLLATDPDREGEAIAFHISEEIKNPRLKVARVEFHEITKKGVDHGVHNPRKLDENLYDAQRARRVLDRIVGYDVSALVWSKLAFGLSAGRVQSVALRLIVDREREVEAFVPEEYWNIAVGLTAASPPQRAPFVAKLASADGKKLEVTNGEVAAKVRADLETARYRVAKVARREQKRNPPAPYTTSKLQQDATNYLHFGAKRTMQIAQALYEGIDLKRDGGPVGLITYMRTDSTRVSDDAVAEVRGVVAKRYGKEFVPERPNVFKSKKNAQDAHEAIRPTSVEIHPDSIKKHLKDEQYKLYKLIWNRFVASQMNPAVYDRTTVEIDVAPTVAEPAHRSYLARASGRILKFAGWLQVTEGQQEFAGEEESAGAAADGGGGAAAERRRGGAGGAGAVGRGGLGGAPARHEGGRGARRDAAGRRHRPEVHAAAAPLQRGLAGARAGEARHRPPVDVRRDHQQGAAARVRGEARGRRVPADAAREVRGRRPRPVEPRHHGSELHRADGGGARRGRRRQPEARAAAQALLQEVPGAARQVEEARAVEARGGEDRHRLRRVRVDDAQEVGQERLVLELRALPEVQGHPRPVRRARDRRRPRDRHLVRQVREADDHQDGALRRLPVVHRVPGLQEHAPGAARRRVPELRGRSHRDPAPQEGRAHLLRLLELERRAEVRLQALAEAGAGPVPPVRREVRHPHRRQEGDARLRDKGLRVQAGDRRGRGGGGRRGRVRPPRRRGDRRERRGGAGRSARAAGARAGRPARGRAEGGSRKARAGRARTAHGELRRPRDLPPW
>NC_021658.1|WP_020738109.1|8813693_8815136_-|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO
MNGAESRRDDVVVVGGGLAGCEAAYQLAQRGLRVRLVEMKPHKRTPAQTSDRLAELVCSNSLRGAALSNAVGLLKEELRRVGSLALRCADETSVPAGGALAVDRERFAEAMTRSIESHPRIAVERREVTEIPAERPAILATGPLTSDALAASLAAAVGAEHLAYYDAIAPIVSADSIDWSRVWKQSRYGKGGAVRGERAAPAEGAARPEPTAPPPEDAAERRDDAEAGDEAYVNCPFDEAQYKAFVRALVASEKVEARDFEEVRYFEGCLPCEVMAARGEQTLAFGPMKPVGLTDPRTGRRPYAVLQLRPEDEAATAYNLVGFQTRMKYAEQLRVFRMVPGLEEAEFLRMGSVHRNTFVDAPALLGPAMELRALPGVHLAGQISGVEGYVESAAAGFVCAILLAQRLRNEPLRPPPPTTALGGILTHLGRKQPSSYQPSNITWAHIAPLDPAHGKLRKRARYEAMAERALRDLDAWWAAG
>NC_021658.1|WP_044986311.1|8811930_8813415_-|DUF2330-domain-containing-protein
MKLRLLALLALAVPSATLLSPREALACGGCFAPPTETTVVNAHRMVLSVSPVQSVLWDQIQYSGDPREFAWVLPVKPGATIEVGSDAWFETLDAATSVRITAPNSFCASSGGGCGTLASADSEGGVAGAFGNDQVTVLHRGTVGPYETVTLTTDTPGALNTWLERNGFGVDESTQPVIDAYVEEQFDFIALKLQPGKDVKEMKPVRVVMPGANATLPLRMVAAGTGANVAITLFTISEARLAPEGFAAAAVPVDLLAWDFASQDSNYGELREKALAAHDGGRAFLTPYAQQGSLFSPVSSSAAPFGVQYTTSGSTTPVDTIAAAFAQQGLANRETQDTECAVRFAEIATETRAVASPCPAGVPLSDPSCGEVAAGQIDARELACGPLDDLAVAMIGLHPRDVWLTRLEANLPRAALDTDLVLSPAKQERVDNWMRARLSVHAEVLCGAALPLVDGDRAARTRGQGTLVGMTLGALALAAAIARRGARRFASRPA
>NC_021658.1|WP_020738107.1|8811706_8811922_+|hypothetical-protein
MCHLAKSRSRRDARGGSGATWQLATQGHRATAPPGQTGEATAPGFVYGFLAVAFRVLGKRVVRPRARDVDA
>NC_021658.1|WP_020738122.1|8827029_8827422_+|hypothetical-protein
MELSRLLDELTLAANRVGIAVRMEAFDPHLSDARNPRGGLCTVLGRRVILVDANASLPDRIATVAAALARVDLESVFLPPIVRATIGAHARGARPPAPTPGEPVRLPTRQGKRGRASTLLPLARTKWRNS
>NC_021658.1|WP_044988946.1|8827503_8830254_-|alanine--tRNA-ligase
MATPASSDLIRRTFLEFFAQRGHEVVPSAPLLPQNDPTLMFVNAGMVPFKDVFTGKDKRPYQRAASSQKCIRISGKHNDLENVGVTARHQTFFEMLGNFSFGDYFKEDAIAFAWELLTKVYEVPPSRLVVTIYNGEGGFPADDEAAAIWRKVTGFGDDRILRLGLADNFWTMGDVGPCGPCSEIHFFHGNEPDVSRFGEEPRIDGTGWTEIWNNVFMQYERAEKDGPVVPLPAPSIDTGMGLERIASVLQGVTANYDTDLLRGLVDKAAELSGKPYTGGSADDDVSMRVIADHARTTAFLIAEGVMPERQRREYVLRRVMRRAIRHGHRLGIDRPFLHEVALEVVRRMGETYPELRDRRELIARVTEDEEIRFRSTLKRGMKILDERFDEMRSSGERTLPAAAAADLYTTYGFPLDLTQVICAESNFDVDVQGAEAVIRGAAEADGPIDPNAAVDAAHREARAKLAQPVVFTGYEREEGDSEIAAILRVEVQGEGDRARKVRTLVERAEAGEAVEIVVRETPFYAESGGQVGDGGELTADGARVEVKDAQKPVAGLVVHEGVVREGAIAVGQRVHLEVDHAARSATRRNHSATHVLHWALRKVLGEHAQQKGSRVGPDILRFDFTHNRPLTREEIARIEDLVNEKVLTNAKVTTEILPMDEARRRGAMAIFEEKYGDTVRMLTMTPEVVELCGGTHARALGDIGLFKITSEGGVAAGVRRILASTGLNALAYARGVEAELARARQVAKAQGGDLAEKIGKIVAHERELEKKVADLERRILEGGAGPAQGGGGGGIDAMLEGAREIGGIKVLARRVPDGTNPGALRDLAEKLRDKLGDRAAVLLGAAVGDKAQLAVMVSKPATERLKAGELIKPIARIVGGSGGGRPDMAQAGGTDVAQLDAAIAATYVEVERALAS
>NC_021658.1|WP_148314911.1|8830445_8831285_-|HEAT-repeat-domain-containing-protein
MVRRLFIAMFLATSMVFGATSLSSAQDADTSAFRDIAVGKDYRLRVAAALALGRSKSPGARPALEKALKDPHPAVRASAAAALGALGNPAAVPALKAALTVESTPSQKRPIQAAIERLSKLSAKARFLVSLGKFENRSGVKDAMLGSLLKQQTRNRVMQFADIEIVADGADVAAEGKSRKLPAFTLDGSVTHLSKRHGADGVGYAAKVEFVIREMPSQTLKGSMTGSAQAVAEARRARGRQELAQLQTDAVAGAIESALQRAPLALEAASGSSVVPAGR
>NC_021658.1|WP_020738125.1|8831571_8833794_-|TIGR04551-family-protein
MPISSRSTGTSCSPGTPRRRLRSGLALALVLGASSASAQPARRPAQPPAAPPAGQPGAPAPQPGAAPAQPGAATAAPAQPGAAQPGAAQPGATPAQPGAAPVGGSDVEALEPPAPAREPLMPPAETAAPAAPQPARPAASEGPAAAAEGTERKATQGEIGARPSEVYAEDWWSHARPTFEFHGYYRLRWELFNSFALGRVDPRDKALWPQPADNSYDSSHFVNLCDPSETTSGGSRDFHWCKSDTQAGANMRFRLNPELHISDNLRILSQVDLLDNVVLGSTPEGYTNRPRAGGGYEVARRGGYSPLGAFSSTQWAPSAGVNAPRDSISVKRIWGEYMTPVGLLRFGRMPNHWGLGMVANSGDGHDSDYQSTVDRLMFVTGIKKYDLYFAGAWDWANEGATSASLQELEGQPYDLAQSDDVDQYVFVAVRRKNPELQKLELARGNAVMNGGVYFAYRKQTLANDNTSSPGGEDNTASLGQTIDNVASGYVHRGAEMVIPDVWFQLLYKKFRFELEAAMIYGSLDLRGQDDSDYANALSPEDTGWGVRQFGIATQAELTEMEGRLRIHFGFGYATGDDDVPSLKPSGDGFMDPQNSTDRTYSTFRFHPDYRVDQILFRNILSRVQGAYYFRPGVDWDFARDKNGQRAGLGAAAIWSRASEFVQAPGNARDLGIELNGQLYFQSKDGTLNDDPDKMGGFYTAVQYGVLFPLGGLGQLQGEKNLQPIDLETAQTVRWYLGILF
>NC_021658.1|WP_080682373.1|8834231_8836367_+|OmpA-family-protein
MRTLRALCLLSIVGAGVGLASGAARAQEAVREGEFSVQRFEPAPGSRNYLSVEGARMEASLGITAGLMFDYAREPFVLESCVSTTDCSSPDARDHRELPVISDMLTWNLLASITPTSWLQAGLRFPVAYVSGQGVDAATGAAAAEGLKAFGAGDPTLEAKVRFFGGPRDPLVLGAAADVSFPLGHATSEGSYLGSSSPVTAGLRLIVDGSAGPLSFGLNLRGKLLPEAARIASTEVGPVEFGYGGALGYQITPVLRVLAEGYGATQFSAQGGTNSLEVDGALQIAPRDLGLVFTVGGGAGVVEGIGVPVARGIAGILFVHEPGDGDADGVGDAADQCPALPEDRDGIADADGCPEDDGDGDGIPDESDRCPAKAEVINGLDDKDGCPDEVSDRDKDRVPDAQDRCPDQAGRVLLPEHYGCPDKDEDGVPDRVDKCADAPEDTDGFEDEDGCPDPDNDRDGVLDQQDECIDQPEVKNGFKDEDGCPDELPDSDGDGIPDEKDRCPKQPENLNGVEDLDGCPDRGASLVQVGDDDIKILQRVEFALNNDKIQGAQSFAVLDAVVSALSLHPEIFKVEVAGHTDDAGPADMNRSLSQRRAEAVVAYLTSKGVDRARLVARGYGPDKPIDDNKTAKGRQKNRRVEFVIVHSVKKPQQASGEPGATAPSPAAPTMVPSVPPAAAPTAAPAAPPRAAPPRAAPPAAPLPLAPPPPKP
>NC_021658.1|WP_044988948.1|8836505_8837297_+|OmpA-family-protein
MNRTLIALPLVLSSLFAAGCGHSEQEWKAQLGKYNDLQKRSQKREAELEKELADAKQRVEELEKKLADQGADISKMSSTLEDREKALAEYQARAKQLEAIQARFDLLRKKLEELTKLGLEVRVRRNRMVISLPGDVLFDSGKDTLSKEGQEILKKIADVIRGDKSLVDRDYQVAGHTDSQPYKNGPFFDNWGLSLMRARSVLLFLIGKDGRLPTRHWSAAGFADTDPVADNTTPAGKQKNRRCDLVVVPDVDEMLDLTKLATK
>NC_021658.1|WP_020738128.1|8837836_8839387_+|hypothetical-protein
MPRWFNTGGPCNPDDHYMLPPEERLPGVRDLIDRKACFVLYAPRQIGKTTSLLTLAQALTREGRYVAVRVSMEVGAPFPDDPGAAELAMLSEWRGLAGSQLPAELQPPPFPDAPPGERIGAALGAWAQAAPRPLVVFLDEIDALRDITLLSVLRQLRSGYPGRPHGFPHALALVGLRDVRDYKVASGDSDRLGTSSPFNIKVESLTLRNFTRDEVAALVAQHTAETGQGFQSSAVDRAFELTQGQPWLVNALARQLVDVLVKDRAQPITAADVDRAKEILIERQDTHLDSLVERLREPRIRAVIEPMLAGGTLGDVPEDDRRFAVDLGLVRRAAEGGLVIANPIYREIIVRQLTSGVRDSLPRIPATWLTPDGRLDADRLLDAFLSFWRQHGEPLLGAAPYHEIAPHLVVMAFLHRVVNGGGTIEREYAIGRGRMDLCVRYAGETLAIELKVWRDGRPDPLAEGLAQLDEYLAGLGLQRGWLILFDQRSGQPPIAERTRREHASTPAGREVVVVRA
>NC_021658.1|WP_020738129.1|8839450_8840014_-|RNA-polymerase-sigma-factor
MDPDKLTGAAHAVREALAAQRGALLESVRRRARAGVDAEEVLQRALERALARSDQVRDPARAAAWVGRVVRNVLLDELRKKHDVALPVDELELSSVEEDGVDCGCVLVQADRLKPEYALILKRVIVDGVAVTEVAAELGATPGNAMVRLHRARKALRERLKEHCGTTSARSCSECGCDERGCCPQAP
>NC_021658.1|WP_044988950.1|8840184_8840799_+|isoprenylcysteine-carboxylmethyltransferase-family-protein
MISRPWFALVLYGVYMALAFGWRSLRQRRATGSTGFRGVSGPPGSLPWLGGVLFAVAMLLGLAAPVAELAGWIGPLAEPGSLVVGFGAVAILAGILGTLWSQGAMGASWRIGVSEAERTSLVTRGPFAVVRNPIFSFMMLAALGMALILPNAAALASFAALVTAIELQVRAVEEPYLRRAHGEAYAAYCAKVGRFLPGLGLARR
>NC_021658.1|WP_148314024.1|8843309_8844119_+|hypothetical-protein
MAQAPTDALTTSIGACISRAREVINETWQPLMQATHLGADTEEETRLLQQQLDWQLQTASESLLILLEMLGAPRAAERFTARWDDASGKMSLALDAGDMDYVSCPRFEMLSATFESLVPEATQAVTLRAKQDIVREALECTPKIVKASNKTPNSETDLHTIIHKHMEATFVGYLRKTAIATSPKYYIPDGAFPNLELAIEWKYLRNKDDLKRAIDEIKTDINSYGQSRLYTRFFGVFYQINSSICTPRELKLAFGNPTPSWDMILVTAP

Crispr_ID: NC_021658_34

• CRISPR_ID: NC_021658_34
• CRISPR_location: 8908357-8908465
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NC_021658_34

Consensus_repeat	Method
CGCGCATCGCGGTAGGCGGCGGCCGC	CRISPRCasFinder

spacers of NC_021658_34

>34.1|8908383|57|NC_021658|CRISPRCasFinder
GTAAGCCGGTGAGGTAGGCAGCGGCCGCACAAGCCGCTGAGGTAGGCAGCGGCCGCA

CRISPR arrays and Neighbor proteins around NC_021658_34

CRISPR arrays

The CRISPR arrays of NC_021658_34

>merge|NC_021658|34|8908357-8908465|CRISPRCasFinder
CGCGCATCGCGGTAGGCGGCGGCCGCGTAAGCCGGTGAGGTAGGCAGCGGCCGCACAAGCCGCTGAGGTAGGCAGCGGCCGCACGCGCATCGCGGTAGGCAGCGGCCGC

>NC_021658|34|30|8908357-8908465|CRISPRCasFinder
CGCGCATCGCGGTAGGCGGCGGCCGC	GTAAGCCGGTGAGGTAGGCAGCGGCCGCACAAGCCGCTGAGGTAGGCAGCGGCCGCA
CGCGCATCGCGGTAGGCAGCGGCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_148314029.1|8911323_8912070_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738164.1|8901645_8902173_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|184959
NC_021658.1|WP_020738161.1|8891377_8896930_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_021658.1|WP_020738177.1|8913875_8914730_-|M55-family-metallopeptidase	unknown	unknown	gnl|CDD|377424
NC_021658.1|WP_020738179.1|8916964_8917363_+|hypothetical-protein	unknown	unknown	gnl|CDD|226318
NC_021658.1|WP_020738160.1|8889816_8890449_+|glutathione-S-transferase-family-protein	unknown	unknown	gnl|CDD|223698
NC_021658.1|WP_020738159.1|8889241_8889658_+|VOC-family-protein	unknown	unknown	gnl|CDD|226134
NC_021658.1|WP_020738171.1|8908886_8909390_+|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176868
NC_021658.1|WP_148314912.1|8897495_8901344_-|response-regulator	unknown	unknown	gnl|CDD|274362
NC_021658.1|WP_020738165.1|8902280_8902664_+|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|226769
NC_021658.1|WP_020738166.1|8902705_8904181_-|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225114
NC_021658.1|WP_020738175.1|8912098_8913289_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738180.1|8917359_8918622_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|227277
NC_021658.1|WP_020738167.1|8904177_8905728_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_021658.1|WP_020738162.1|8897018_8897375_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NC_021658.1|WP_020738173.1|8909801_8911202_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379050
NC_021658.1|WP_020738172.1|8909508_8909805_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314030.1|8913353_8913737_-|DUF4180-domain-containing-protein	unknown	unknown	gnl|CDD|379371
NC_021658.1|WP_044986317.1|8915407_8916340_-|DUF2935-domain-containing-protein	unknown	unknown	gnl|CDD|378573
NC_021658.1|WP_187345674.1|8906029_8907721_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|223732

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_021658.1|WP_020738162.1|8897018_8897375_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	1e-20	69.0	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020738180.1|8917359_8918622_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|227277	COG4941, COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain [Transcription].	2.2215e-128
NC_021658.1|WP_020738164.1|8901645_8902173_-|LysR-family-transcriptional-regulator	gnl|CDD|184959	PRK14997, PRK14997, LysR family transcriptional regulator; Provisional.	1.13073e-29
NC_021658.1|WP_020738161.1|8891377_8896930_+|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	1.99443e-150
NC_021658.1|WP_020738177.1|8913875_8914730_-|M55-family-metallopeptidase	gnl|CDD|377424	pfam04951, Peptidase_M55, D-aminopeptidase. Bacillus subtilis DppA is a binuclear zinc-dependent, D-specific aminopeptidase. The structure reveals that DppA is a new example of a 'self-compartmentalising protease', a family of proteolytic complexes. Proteasomes are the most extensively studied representatives of this family. The DppA enzyme is composed of identical 30 kDa subunits organized in a decamer with 52 point-group symmetry. A 20 A wide channel runs through the complex, giving access to a central chamber holding the active sites. The structure shows DppA to be a prototype of a new family of metalloaminopeptidases characterized by the SXDXEG key sequence. The only known substrates are D-ala-D-ala and D-ala-gly-gly.	1.18951e-113
NC_021658.1|WP_020738179.1|8916964_8917363_+|hypothetical-protein	gnl|CDD|226318	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown].	8.69803e-16
NC_021658.1|WP_020738160.1|8889816_8890449_+|glutathione-S-transferase-family-protein	gnl|CDD|223698	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	9.73527e-29
NC_021658.1|WP_020738159.1|8889241_8889658_+|VOC-family-protein	gnl|CDD|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	5.94025e-60
NC_021658.1|WP_020738171.1|8908886_8909390_+|SRPBCC-family-protein	gnl|CDD|176868	cd07826, SRPBCC_CalC_Aha1-like_9, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	1.76747e-71
NC_021658.1|WP_148314912.1|8897495_8901344_-|response-regulator	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	3.19126e-52
NC_021658.1|WP_020738165.1|8902280_8902664_+|DUF4440-domain-containing-protein	gnl|CDD|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	7.00994e-14
NC_021658.1|WP_020738166.1|8902705_8904181_-|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	2.89564e-177
NC_021658.1|WP_020738167.1|8904177_8905728_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.56559e-41
NC_021658.1|WP_020738162.1|8897018_8897375_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	6.66454e-17
NC_021658.1|WP_020738173.1|8909801_8911202_+|AAA-family-ATPase	gnl|CDD|379050	pfam13175, AAA_15, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	3.64954e-18
NC_021658.1|WP_148314030.1|8913353_8913737_-|DUF4180-domain-containing-protein	gnl|CDD|379371	pfam13788, DUF4180, Domain of unknown function (DUF4180).	3.26824e-22
NC_021658.1|WP_044986317.1|8915407_8916340_-|DUF2935-domain-containing-protein	gnl|CDD|378573	pfam11155, DUF2935, Domain of unknown function (DUF2935). This family of proteins with unknown function appears to be restricted to Firmicutes. The structure of this protein has been solved and each domain is composed of four alpha helices. A metal cluster composed of iron and magnesium lies between the two domains.	2.57738e-15
NC_021658.1|WP_187345674.1|8906029_8907721_+|STAS-domain-containing-protein	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.95168e-106

Protein sequences

>NC_021658.1|WP_187345674.1|8906029_8907721_+|STAS-domain-containing-protein
MTSWKEMVAPRSLADNLLSGLTVAFVALPLNLALALACGLPASAGLITGAVTGVIAALFGGSRLQVTGPEVALVPLTFEILQRHGPHGLLCATFLCGVLQVLMGVARVGRLIHMIPVSVIGGFMAAVGLLVFNSQLPRLLGLPAEMRLVSSLPGTGWLAHVDPFAVGIGALVVAATVLLPKLHRRLPGGLIGLGAAVLAVSALGAGTASVGPISASFPAPSLPAFDRLELIAILPEAIALALLASIDSLLSAVAIDAQSNAKRHSSEQELMAQGVANMVSSMIGGMPVAGAIVRSSAALQCGATTRLAALTQSVTLLGLLYLARPFVERLPLAGLAGILLVVGYRLINWQQVRLMWRVSRFEAFVFVATAASIVATDFVGGVLMGLVLSLVHFAHMQRRVDVSLVTATDEPEEMPRLLELPARRSLGPTPPVAVVRVEGPIFFASHTEIRSLAEGGPLPRHLVFDLAGVPLIDCTGIEAFRALLGKLREQGTRALLSRASDRVADRLQEAGLLQAFIGGRVFSTVAEALESLDEPAARASVFEARRQQPPSPLLRPEAPAGAS
>NC_021658.1|WP_020738167.1|8904177_8905728_-|HAMP-domain-containing-histidine-kinase
MRLLTRLVLSHTAPVLVMLVALGVVLGSLAQITSSLQNLLSDETEELRREAALHHAAWAMGLAMRRGQEACSRGAPWDEVAPILRTRIAALKAEVGEPALLPSDPMLPSIDGHLQLAQGALDGGTCGHLTDPDVQHERVRLDEQLTDAWVLRIGELQARVRVKEEDARGASASALSNGLAISIAACVVAALLAHRIARTVTEPLAAIATQAQRLGKGQFDAAAEVRGPAEVRDLAREIETMRRRLAEIETLKQGFLASVSHELRTPLTKIREAISLLEDGVGGGALSERQTRILHIARVACEREIRMVTTLLDLSRLSAGSPIRLQDGSSIDDLIRSAVRDEEAEARERGVSIEVETPGDVPPCSLDVALVERAVANLVRNAASVSKPGQRVLVRRELAEDTRGGRPGRRVTISVTDQGPGVPGEIRQSLFEEFKTQPVANSPKRVGIGLGLALSRKIARAHGGDLELDDHAASADAGAGQDARAAGATFRLWLPLSTERSSEQAPAALHPAPAVP
>NC_021658.1|WP_020738166.1|8902705_8904181_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MSPARKPHVVIVDDEPHLCELLAFRLEHHGYRVTTELTGAGGIAALSREPVDAMIVDLRLDDCDGLDVLSEVQKRSPDVPVVILTAHGTIEIAVEAMRRGAYGFLTKPFHDLDLLQKLAHAVESSSLRREVAGLRRIIGAQSDELRLLGTSDRIAAVREIISRVAPTDATVLLLGESGTGKELAARSLHALSQRRGKPFVAVNCSALPAELLESELFGYVRGAFTGATRDKEGLFASANGGTLLLDEIGDAPPAVQVKLLRVLQERRITRVGSLNEEEVDVRVVAATNRDLLTEVRDGRFREDLFYRLHVVPIVMPPLRERVEDLPLLCEVFLSRAAARHGLSEPKLTPEALRVLLAHPWPGNVRELANVMEGAVLLCRGERLQPQDLSTLLVPPARKLDGWSSGAEPEDAEAPAISDAAGEILSVAFGDPGSALPSLKEARDTFERAYLVEVLRRANGNVSAAAKLSGRNRTDFYDLLRKHGLSSASFKE
>NC_021658.1|WP_020738165.1|8902280_8902664_+|DUF4440-domain-containing-protein
MDVKEPQQMNAIFADAFNAGDLDRIMALYEPGAVLAPAPGQRAAGAPAIREAIGALLALRGRMASKNNYCMQAGDIALLQGEWRLSFVGPDGEEVTETARSAEVVRRQPDGTWRYLIDHPAGDDTPR
>NC_021658.1|WP_020738164.1|8901645_8902173_-|LysR-family-transcriptional-regulator
MIDLNEMVCFAHVVDQGSFAAAARRLRIPPSTMSRTIAALERRLGARLLERTTRKLRLTDAGAQYHERCRRIVAEAEEADRLMEARASRAQGTVRVSVPEAFVERLLAPAVTRLLATYPDVRVECLTDDRYVDLVGERMFAVTPSARAAPAHVRVFLDLLYEHVRQHPRLLDAAA
>NC_021658.1|WP_148314912.1|8897495_8901344_-|response-regulator
MGALIRSIDWSRTALGPVEAWPQSLRTALSILLSSEHPMFLWWGRELIQFYNDGYRPILGSKKHPAAMGQAGRACWKEIWDVIEPMIEKVFAGGATYLRDGLLILDRNGFLEECYFNYGYSPIRDERGAVAGVFVACSESTGHILGQRRLKLLAALGARVADAKNVEDACRVMLDTVAEAGRDLPFALLYVADEGGAQARLAATAGLDPGHAAAPAAVSLDAASAAPWPLHRALCEEAEVDLAELPAGVGPLPGGPWPDAARRAVVLPLPRAGAGGRAAGFLVAGVSPRLVLDDDYRAFLRLVAGHCATAIQSARASEEEQRRQQALAELDRAKTAFFSNVSHEFRTPLTLILGPVEDGLSDAEQPLPPRQRERLAIVHRNGLRLLRLVNTLLDFSRIEAGRVQASYQPTDLGAFTADLASSFRSLLERAGLSLTVDCPPLAEPAYVDRELWEKIVLNLVSNAFKFTFTGGVRVSLEAAGGRAVLSVEDTGTGIPEAELPHVFERFHRVEGARGRSYEGSGIGLALVQELAKLHGGAAAVESRLGEGSRFTVSIPLGTAHLPEDRVARASPPAAGGRDAAPFLDEAAQWLRGEQAPASRPAAEGPARKLPGRVLVADDNADMREYALRLLVAEGWTVEAAVDGRAALERARAHPPDLVLTDVMMPRLDGFGLLRALRADERTRGVAVVMLSARAGEEARVDSLEAGADDFLVKPFSAKELLARVRVHVELARRRREAEGQRQYLNDLFMQAPGPIAILRGPEHVFEVVNPLYQRLVGGRALVGEPIRAALPELEGQGIWELLDAVVRTGEPIVGEELPVRLDRRGDGTTEEVFFNFVYQPLRDRDGAVEGVFVFAFDVTDQVRARRRVEALVAALKVADQRKDEFLAMLAHELRNPMASISLSLTLLDDVDGDGPTSARFREIARRQMGHLVRLVDDLLDVSRITRGTVELRLGDVDLAAVVHDAAAAARPALEARRHALSVSVGPGGFGMRADATRLEQVVTNLLTNAAKYTPPGGSISVRLTREAAGGAPEAAVLRVRDTGRGIPSAMLEKVFDLFTQVDQTIDRRTGGLGLGLTLVRRLLELHGGSVIAASAGPDQGSEFTVRLPLGPGAAPQPAPSAGPLARRDRPPPAPREGPPPAPREGSPPTPAPRAEAPDAAADRRRVLVVEDAEDVRRVMRAYIEALGHEVTVAVDGLEGVTKLLELRPEVAFVDIGLPGIDGYEVARRARAAPGGEALYLVALSGYGGPDDQARSRRAGFDRHLIKPVGGATLQDVLTAPRT
>NC_021658.1|WP_020738162.1|8897018_8897375_-|winged-helix-turn-helix-transcriptional-regulator
MTPSERLDATFAALADPTRRAILARLASGEASVTELAKPFAMSQPAISKHLKVLERAGLISRGRDAQRRPCRIEAKPLADASGWLDNYRRFWEGSYERLDDLLEELKERESKGERSTR
>NC_021658.1|WP_020738161.1|8891377_8896930_+|AAA-family-ATPase
MIVERGYLLREKIEETVDFTLYRAYREGDSVPVLLKILRAERATGAEIARFKHQYERAARLASPRLVALRGVEALAGSLIVVLEDFPGRDLARILAARPSRRMPVGEALDLAAALAEGLAAVHAAGLVHRDLRPQNVLVGARGAVKINGFGVDAEITRAHERLYAPAVIAEVLPYVSPEQTGRMNRGVDYRTDLYALGVILYQMLTGQRPFEALDPMELIHAHLALSPAPPSRVDPTIPEAVSDVVLKLLAKNAEERYQSAEGLLADLERCREALRGTGTIEPFVAGQRDRQDLFRIHQKLYGREHDIETLTAAFERALEGSREIVIVSGYSGIGKSSLVHEILKPLARQKGYFTSGKYDQYNRGAPYSAVIQAFDGLVRQILTESDARILRFRSALLEALGPNAQVVCDVIPSLGHVIGPQSPVPALGPIEAQNRLNRCFLLFVSACARRAHPLVLFLDDLQWIDPASLVLLRALLADDSLDALFFCGAYRDNEVSPGHPFVLAIEELKRAGLVVRNIVLAPLARPHLIEMLSDSLKRSDCGPLADAVQKKTCGNPFFVKEFVRSLHDHGVLAYAAGSGWRWDLAAIDALRYTDNVADLMVRTIARLPPATVKALNLAAAIGNRFDLDVLAAVNECSTEDAYARLDLAVSEGLVIAGRGGYRFAHDKVQEGAYAMIPEVDRPAFHLRIGRLLAGKLDLSESQSLFDVVRHLNSAGDLVSDPAERLHLARMNLEAACRAEDSAAFGAALRYLQLGLLRLPEDAWASQYPLRLEYAKRTALMLSLCGRHDDALAILADGLERAASRLDRTEVLRLKMNVQVLKNDLPAALAEGLEALRPFGIDLPPFPDDVTLDAQVRATMDLVRERTIEALPGLPPLADPEILAMQDVLQELFLPCYFLATNNLGITVAQILESTLRHGLSKNSIFGCMNFGMLLCARGDIALGYRFGRAAVDLADRYTDKKSEAMLRNMWGAFVQHWREGYATCKASLVAGMHAGLETGQYIWSFYNTANGITNSLLRGLPLSDLLAEAQSYQPMRKLDEFNAITWAVGAVGQMAHQLSVETERPATLKGAWVDIDEVIEESRRIDNQASFFFAHFYIVVLCVFQGAFEEAARAALLPNMEIPAVAAWHGTPAFHCYAGVAFTQAADVVSPEERALFLARAEVSAEKLSRWADLCPENLAHRRALLLAELERARGDARAAGDRYDEAIALAQRGGYLHDEALGNELAGLCFRALGKETIAGAYLTKAHRAYGRWGATEAMRRLERAYPDLIPGEDLRGERSPQAGAALDVGSVLKASQAISGEIVLDRLLDALMRIMVENAGARRGVLLLLRDGRLVVEAEHHIRDASVHVLGAAPLEGRKDLPASVVTYVARTRETVLLGDLAMDGPFGRDPCFAGGAPRSSLAAPIVYKGHLAGVIYLENDLTRAAFTPDRVEVIRLLSAQAASSIENARLYADLQQENAERRRAEEVLRHSYSLLEATLESTADGILVVDDEQRVVRQNHRFSAMWRIPDEILSTGSDDTFRTFASDQVLDPEGFLQRIRALYASPEESSVDTIPFADGRVFERYSQPQRLGGRVVGRVWSFRDITARVRAEQRRDQLLLDERRARTAAEEAVRLRDEFLSIASHELRAPLTSLQLAIQSLGQRLARGTDLERVRSAVALSVRQVKRLTDLVDMLLDVSRIQAGRLELCTAPVELRALVDEVVALLGHQITQSGSAVAVRAEQPVIGRWDPHRLEEVVTNLLTNALKFGERQPIDIAVTQEDRVARLSVTDRGIGIPAEVQAQLFERFRRGVSSKHFGGLGLGLYITRTIVEAHGGRIRVSSEVGRGSTFCVELPLSTERAGDLSS
>NC_021658.1|WP_020738160.1|8889816_8890449_+|glutathione-S-transferase-family-protein
MIKVYNFARGARGLRVMWQCEEMGLPYEVEMISYPPSEAYRALHPLANVPFLEDEGGVAIHESVAMMLYLAQKYGPTPLLPDKDDPALARVLQMTVFGEAAIGAGVNALLTAHFGAPEADKRSWSVVTHEANVERALRFTAGLLDDRPFLAGERLTLADISVSTAIGIYRGALGKALPDALAAYQERLAARPALERARARCRGEESPTRA
>NC_021658.1|WP_020738159.1|8889241_8889658_+|VOC-family-protein
MTTNTPRKLFVNLSVRDLKRSMEFFSKLGFEFNPQFTDDKAACMVVSEEAYVMLLAESFFKTFTKKEICSTSTHTEGLFALSCSSRAEVDDMVKKAIAAGGSHALDPQDHGFMYGWSFYDVDGHHWEVMWMDPKAIQP
>NC_021658.1|WP_020738171.1|8908886_8909390_+|SRPBCC-family-protein
MVATSAANKDSFQVTTPSEQEIHMTRLFNAPRHLVFEAMTRPEHVKRWWGCLGEGYGVSVCEIDLRPGGAWRFVNRHPHGEAAFHGEYKEITPPSRLVYTEIFEMYPDTVSLVTSVLTEEGGKTRVTTTTRYPSKEVRDAVIASGMEHGAALSYDRLEDLVAQLQQR
>NC_021658.1|WP_020738172.1|8909508_8909805_+|hypothetical-protein
MLDFLPEASHLPAAARDLSAACGRTIALSSAEHRGRLDVSVVELVERRGFMPRVSFRKRPTPEHRESLARPSRHPRPAPCRKLRCLIDEPLATAASAR
>NC_021658.1|WP_020738173.1|8909801_8911202_+|AAA-family-ATPase
MKITFSNLGTIKKTELDLRPLTVIIGPNNSNKTYVAYSLYGLWQAQIEGTTVSDVSDLVPWKRSAAELYFRIDSRLTARVNEYLQDVAVLFREEMSSFFQDSSGKLFSRSRVEVELTQNDLDAAFEKVIAKVRIGSVSKRGEKVLLSAPPPKGQTGATGRSGFSLEGRAALLLSRALRFLFQKPLLLPAERNAFIMTYKMLASRRYNVLRDAQRSLLGKRHVSKRQLDLLREQGDIRYPKPVEDFLDFLTDIELSEAEDSDDAAAREPFRALAADIEESIQNKNKTRFRRTALGGREIQIDVRKGLSIDLYNASSSIKQLTPLLLYLRYRAKPNDFLIIDEPEMNLHPESQAKLLEILGILVNLGVHVLLTTHSPYFMSHLNNLAAGDTSDPEVLKRQAASLYLGDPRAFVPMDKVSAYEMRDNELRSLKDEDYGIRWDTLSDVSSALQQKYFEISETGRAGRGER
>NC_021658.1|WP_148314029.1|8911323_8912070_+|hypothetical-protein
MKFGISSKIKDEGVCVLFGVDRERDPLMRGRGVARPDYLVLYASRERCLVTIIEMKGTDRHKLEHGIDQIKALRDRLREEIEAHLPGACGGMVKFQGILLTPFNADIPRAKIQREAASGFTILPLQYGQKAELYRYVRTELRSTDRYVHEKLPRDADELNFIEKILVHAALPERIEGALPAAKLGSGIDVHYARPDDGHDEDHAALIADRTGAQIATPARCAGFRRKIEDELRHLGLRYARLQFTSVP
>NC_021658.1|WP_020738175.1|8912098_8913289_-|hypothetical-protein
MPVWPIVPSPPPQQADVDRALDGATAAWLVADSGRRARIPRSGIEALRPLLRLRGEGAPRSEGAGSEEPALAPVTLELERHGRPSATVRVAADLSIQLAWDRPAPVEAPAALRAWLVGRGAALRPPSPERGHAPAASAAAGEIAPPGTTLVAAASSTYRRLCTDGARVFAIQGWTLVRLQKGQRAHEICPVFRPDTPIAIRAGGVLLLDPSGRRRLVTEDGEARPDRRPLFGLPALRLRRALPRFVAARDAALARLVPDDADLLPLDPGHDACDAYEAFGGALPAALRLRSFWGCDVARGLLHEVPARGAPRQIALGGRPAWLGATGTGVLVVVARDGGEVAVLAVDAGAPARSLGAFRGRADGVLAALCVGGEAWLRLAAPPGGVVVALEGAGGA
>NC_021658.1|WP_148314030.1|8913353_8913737_-|DUF4180-domain-containing-protein
MELTLTDEGGVKFVEGVPDEAFLSSDRDVDRVLEACFSDGVRCALLYAANLPAAFFDLSSRQAGEILQKLRNYWVRLAVVCPPGGPGFSSRFGEMLAEERRGAYFGVFETRDAAVEWIRETSDAEQA
>NC_021658.1|WP_020738177.1|8913875_8914730_-|M55-family-metallopeptidase
MFVLISIDLEGCAGVVHVDQTRRGGGDYERARAWMSREANAAALGAFEAGATRVVVNDSHADMRNLLFEELDPRVEVISGALKPLSMVQGMDAGQPAAAFFVGYHGGAGLRASVLDHTYYGAVVGEIRLRPASGAADDPGLWVDEAAINALVLGEAGVPVALVTGDEAVTAHASERFPGVTTVAVKSSITRYSARSIHPDEACRRIRAAASEALRGLARVRPYTLPPPIGVTFSLLTTAYADAAELVPGVVRLDARRVSYVAPTAREVLRAVLAITKIAGTVVV
>NC_021658.1|WP_044986317.1|8915407_8916340_-|DUF2935-domain-containing-protein
MDKRALQGKLGRRQFAGRAAATAGISLLATPGLAIGAGKGADSESVGPISLPEGAAFTPGVYVDQRARKPIYLPGANAGYAAHAVSEVLFWTDQLMEHGMFIALLMPGDRLRGPRSEARQFQMTFAGHFLSARDRGYRDDGLSSLLLSTRADVLQFIEYKRRMQRAQEAGTLKSLVWPLFFDHIAREAERFADRLALLAQGSAALQSDEVAAFWTTIMADHLEFVAHLLDPQERALVADAKARAEQLYQTHAHRVGSGQLATMADEVIDFKTAAEHGIEAGQIKSIIDPSLADHVLREAVRFSDEVRRAG
>NC_021658.1|WP_020738179.1|8916964_8917363_+|hypothetical-protein
MKYIMMMHTPHGGPYQVASWAQQDFQAHIAFMKRFHKQLSASGELVAAEGLAGPGQAKLVRAGKDGKPITDGVFPETKEFLAGYWIVDVDSPERAYELAAQASAAPGPGGAPLNLAIEVREVMSAPPPQELP
>NC_021658.1|WP_020738180.1|8917359_8918622_+|sigma-70-family-RNA-polymerase-sigma-factor
MTSRPRDTGAERLLRDLAPQVLGAVLRRFRDFGAAEDAVQEALVAAATQWPRDGVPDEPRSWLIQVASRRITDHVRSEAARRRREAFVVSLAPPELQIALAADSDEAVEQDDTLTLLFMCCHPALSTSSAIALTLRAVGGLTTAEIARAFLVPEATMAQRISRAKQTIKASGVPFQMPTSEERSARLGAVLHVLYLIFNEGYTTSSGPALHRDDLSSEAIRLTRAVHALLPDDGEVAGLLALMLLTDARRAARTGPEGQLIPLADQDRRLWDQGAIAEGVALVTATLSRGSIGVYQVQAAIAAVHDEAARAEDTDWPQILALYDLLLGMSDNPMVALSHAIATAMVRGPEAGLELLRSLDADPRLQGHHRLDAARAHLLERAGDREAAIAHYRRAAGRTTNLPEQSYLMSQAARLLDARK

Crispr_ID: NC_021658_36

• CRISPR_ID: NC_021658_36
• CRISPR_location: 9128740-9128910
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_021658_36

Consensus_repeat	Method
GGCGGCGCCGGCGGCAACGGCGGC	CRISPRCasFinder

spacers of NC_021658_36

>36.1|9128764|15|NC_021658|CRISPRCasFinder
AACGGCGGCGCAGGC
>36.2|9128803|33|NC_021658|CRISPRCasFinder
GGCGGCAACGGCGGGACGGTGTGCACAAGCGAG
>36.3|9128860|27|NC_021658|CRISPRCasFinder
CGCGGCGGCAACGGCGGCCAGGGTGGG

CRISPR arrays and Neighbor proteins around NC_021658_36

CRISPR arrays

The CRISPR arrays of NC_021658_36

>merge|NC_021658|36|9128740-9128910|CRISPRCasFinder
CAGATCTCCAGCGGCAACGGCGGCAACGGCGGCGCAGGCGGCGTCGGCGGCGCCGGCGGCAACGGCGGCAACGGCGGGACGGTGTGCACAAGCGAGGTCGGCGCCGGCGGCAACGGCGGCCGCGGCGGCAACGGCGGCCAGGGTGGGTACGGCGGCGGCGGCGCGGGCGGC

>NC_021658|36|32|9128740-9128910|CRISPRCasFinder
CAGATCTCCAGCGGCAACGGCGGC	AACGGCGGCGCAGGC
GGCGTCGGCGGCGCCGGCGGCAAC	GGCGGCAACGGCGGGACGGTGTGCACAAGCGAG
GTCGGCGCCGGCGGCAACGGCGGC	CGCGGCGGCAACGGCGGCCAGGGTGGG
TACGGCGGCGGCGGCGCGGGCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_044986336.1|9119507_9120899_-|hypothetical-protein	unknown	unknown	gnl|CDD|366454
NC_021658.1|WP_020738313.1|9115979_9116828_+|DUF1449-family-protein	unknown	unknown	unknown
NC_021658.1|WP_020738325.1|9136184_9136616_+|CBS-domain-containing-protein	unknown	unknown	gnl|CDD|341361
NC_021658.1|WP_020738307.1|9108260_9109571_-|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NC_021658.1|WP_044986337.1|9121307_9122918_-|DUF1552-domain-containing-protein	unknown	unknown	gnl|CDD|377875
NC_021658.1|WP_187345680.1|9116979_9119202_+|hypothetical-protein	unknown	unknown	gnl|CDD|225177
NC_021658.1|WP_020738308.1|9109646_9110090_+|BON-domain-containing-protein	unknown	unknown	gnl|CDD|335963
NC_021658.1|WP_020738306.1|9106951_9107740_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|181382
NC_021658.1|WP_020738324.1|9135066_9135957_+|hypothetical-protein	unknown	unknown	gnl|CDD|238571
NC_021658.1|WP_063752049.1|9137889_9138672_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197666
NC_021658.1|WP_020738311.1|9113442_9114894_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_044986341.1|9136612_9137605_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|226651
NC_021658.1|WP_080682400.1|9139806_9141603_+|hypothetical-protein	unknown	unknown	gnl|CDD|378931
NC_021658.1|WP_148314059.1|9112340_9113456_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738320.1|9129783_9131955_+|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NC_021658.1|WP_187346055.1|9134134_9135070_+|pseudouridine-5'-phosphate-glycosidase	unknown	unknown	gnl|CDD|377251
NC_021658.1|WP_020738309.1|9111001_9112339_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738319.1|9129310_9129589_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314061.1|9132181_9134068_+|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|224490
NC_021658.1|WP_049949696.1|9138712_9139288_-|hypothetical-protein	unknown	unknown	gnl|CDD|275110

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_044986336.1|9119507_9120899_-|hypothetical-protein	gnl|CDD|366454	pfam01082, Cu2_monooxygen, Copper type II ascorbate-dependent monooxygenase, N-terminal domain. The N and C-terminal domains of members of this family adopt the same PNGase F-like fold.	2.09674e-09
NC_021658.1|WP_020738325.1|9136184_9136616_+|CBS-domain-containing-protein	gnl|CDD|341361	cd04584, CBS_pair_AcuB_like, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the ACT domain. The putative Acetoin Utilization Protein (Acub) from Vibrio Cholerae contains a CBS pair domain. The acetoin utilization protein plays a role in growth and sporulation on acetoin or butanediol for use as a carbon source. Acetoin is an important physiological metabolite excreted by many microorganisms. It is used as an external energy store by a number of fermentive bacteria. Acetoin is produced by the decarboxylation of alpha-acetolactate. Once superior carbon sources are exhausted, and the culture enters stationary phase, acetoin can be utilised in order to maintain the culture density. The conversion of acetoin into acetyl-CoA or 2,3-butanediol is catalysed by the acetoin dehydrogenase complex and acetoin reductase/2,3-butanediol dehydrogenase, respectively. Acetoin utilization proteins, acetylpolyamine amidohydrolases, and histone deacetylases are members of an ancient protein superfamily.This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the acetoin utilization proteins in bacteria. Acetoin is a product of fermentative metabolism in many prokaryotic and eukaryotic microorganisms. They produce acetoin as an external carbon storage compound and then later reuse it as a carbon and energy source during their stationary phase and sporulation. In addition these CBS domains are associated with a downstream ACT (aspartate kinase/chorismate mutase/TyrA) domain, which is linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. Pairs of ACT domains bind specifically to a particular amino acid leading to regulation of the linked enzyme. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	5.92812e-44
NC_021658.1|WP_020738307.1|9108260_9109571_-|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	8.21312e-05
NC_021658.1|WP_044986337.1|9121307_9122918_-|DUF1552-domain-containing-protein	gnl|CDD|377875	pfam07586, HXXSHH, Protein of unknown function (DUF1552). A family of proteins identified in Rhodopirellula baltica.	1.14405e-73
NC_021658.1|WP_187345680.1|9116979_9119202_+|hypothetical-protein	gnl|CDD|225177	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown].	3.16434e-44
NC_021658.1|WP_020738308.1|9109646_9110090_+|BON-domain-containing-protein	gnl|CDD|335963	pfam04972, BON, BON domain. This domain is found in a family of osmotic shock protection proteins. It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes.	4.65001e-15
NC_021658.1|WP_020738306.1|9106951_9107740_-|methyltransferase-domain-containing-protein	gnl|CDD|181382	PRK08317, PRK08317, hypothetical protein; Provisional.	3.71565e-25
NC_021658.1|WP_020738324.1|9135066_9135957_+|hypothetical-protein	gnl|CDD|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	1.35205e-46
NC_021658.1|WP_063752049.1|9137889_9138672_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	8.48858e-18
NC_021658.1|WP_020738311.1|9113442_9114894_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.45779e-98
NC_021658.1|WP_080682400.1|9139806_9141603_+|hypothetical-protein	gnl|CDD|378931	pfam12708, Pectate_lyase_3, Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.	4.44349e-14
NC_021658.1|WP_020738320.1|9129783_9131955_+|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	2.67797e-23
NC_021658.1|WP_187346055.1|9134134_9135070_+|pseudouridine-5'-phosphate-glycosidase	gnl|CDD|377251	pfam04227, Indigoidine_A, Indigoidine synthase A like protein. Indigoidine is a blue pigment synthesized by Erwinia chrysanthemi implicated in pathogenicity and protection from oxidative stress. IdgA is involved in indigoidine biosynthesis, but its specific function is unknown. The recommended name for this protein is now pseudouridine-5'-phosphate glycosidase.	1.32873e-175
NC_021658.1|WP_044986341.1|9136612_9137605_-|alpha/beta-fold-hydrolase	gnl|CDD|226651	COG4188, COG4188, Predicted dienelactone hydrolase [General function prediction only].	1.01729e-21
NC_021658.1|WP_148314061.1|9132181_9134068_+|amidohydrolase-family-protein	gnl|CDD|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	4.2029e-129
NC_021658.1|WP_049949696.1|9138712_9139288_-|hypothetical-protein	gnl|CDD|275110	TIGR04292, hypothetical_protein_PF0600, heavy-Cys/CGP-CTERM domain protein. Members of this protein family are restricted to the Pyrococcus and Thermococcus genera of the archaea. Member proteins have a C-terminal, Cys-containing predicted surface anchor domain, where the Cys may be the site of cleavage and lipid attachment (see domain TIGR04288). Members also contain a region crowded with 10 invariant Cys in 60 residues (see domain TIGR04289), possible ligands to some redox cofactor. Note that a sorting motif is CGP. Previously, the motif was named incorrectly as GCP-CTERM in this model due to a typographical error.	0.000140364

Protein sequences

>NC_021658.1|WP_044986337.1|9121307_9122918_-|DUF1552-domain-containing-protein
MNRRLFLRGIGGAALAVPFLNSLVRSARAQEVPSPRRLVIFYTNNGCLTNRWFPTIENGSGSVTAASLEAVQADGKPRTLAPLAPFAAKLLFPRGLAMPLNGFNNKVDGVVHFDPHDQGMGSKLTCAPLDPAGEHWALSHSLDHEIAQRFNQGTNKSPLVLSVGNAFTNVKGIVSYSASKTPYAPVTNARTVYSSLTGLFASGAETEADHRVKRGESIIDLVSADLGAFKARKMSAPDRRKVDDWLSLLRETEQQVVPSACTAEAAAALGVTDAALTEAGYPSRGGGFPNSEKVYTLGSEMMIRLIALTMMCDSNRSIVLQWPGYVTFNWDGIAHTHDHHGLSHRNGSAATGGQCVSGVIEQIHEIDRWYAGRYAKLVKTIDSIEEGDGTMLDNSAVMWLPELADGNAHNNNNLPIVIAGSAGGYLKQGVSVNVAGGNLAVGNSEASCATGAEGEDNSGNTGSSGGTVPLNKLFTTLINALGAGMPDWEPVDRFGVSDAVSAGFGGSAPSFTTDGAGKVIDGPGISNPGELDAIKA
>NC_021658.1|WP_044986336.1|9119507_9120899_-|hypothetical-protein
MRKSMSFVLTPLAFLPALLLGCSGEEAPGSAGTSPTFHRDVEPLLQKHCMSCHSPGNIAPFGLTTYEEARTVAGLMAHATRERTMPPWGAEETDECQPPYGWKDDLRLSEAEIAVLEAWSAAGSPEGDPADAPPPFVPGAGGLSGVELEVAPEEPFVASGDADQFRCFVMDPGLTETRYINGVHIVPGNSKVVHHALVFLDREGASDELADEHGGYDCFGGPGFSGELVAAWAPGSVPLEFEPNIGAELPAGARLVMQVHYHPAGTTADPDTTRLQMRFTKGVPEYSMGVALIGNFETSADEGGGLLPGPNDGDGAEFLIPAGAEDHVETMQFRMPESVSDAEMYLYGAGTHMHYVGTDMKVTLEHTRGDPDNASKQCLVQTPRWDFSWQRGFYYDAPIAELPRIHGGDLLTMRCTYNNSNSNPFLVKALQEQNMPGPVDVHLGESTLDEMCLAALIYVTKRQ
>NC_021658.1|WP_187345680.1|9116979_9119202_+|hypothetical-protein
MPTVTVPLILVLVGVLAFVALGMLVMYAKFYRQVDQGKALIINTRGQDPIVTFTGTLVLPIIHRAEYMDISVKTIEIDRRGKEGLICKDNIRADIKVTFFVQVNKTQDDVRTVARTIGCVRASNPETLEQLFAAKFSEALKTVGKRLNFEDLYKERQKFKDDIIDVIGKDLSGFVLADAAIDYLEQTPIELLDKDNIMDAEGIRKITELTVAQNVLTNELRQKERMEIGSQNLNSDEAIFRFEQRRAEAEAKKAKEIAVAQAREQNEAARITSDERKKTVLLQEKNDEEAFVAREAKERGVQVAQKNKEREVAVETERVAKARELEIVSRERDVSLQQIAREKELELQKKDIADVVRARIAVEKTVAEEEERIKDVRAVAEATRLKDVTRINAEAEAQEQLVKQIKGAEASEEAAKFRAREKLLIADAELEASDKAARAKIRMAEGVQAESAADGLARIRVKEADAQAIEKQGFAEARVALEKMNAAAVGEEKQGLARVLVKEAEAQAIEKQGRAEALVARERLLAEAAGIEQKGLAAARTREAEALALEKTGLAEATAIKQRLLAEAAGTAEKAAAMKALDGVGREHEEFRLRLEKERAVELEALRIRADIARAQAEILRGAFEQAKINIVGGDGAFFDRFVKAVTLGQSVDGMVDQSATVRALVGDYLNGNASLPEDLKQLVAPPSPLARSADGTLSGMLTSLLPSADADGKKKIEALAQKARELGLDQLAQQRTPRT
>NC_021658.1|WP_020738313.1|9115979_9116828_+|DUF1449-family-protein
MAEVLAASLAFPAVIFTVLLALALIYWLFVVLGALDLDLLGGAHGDATPDLGGLEGAAKGALEGAAKGSLEGAAKGSLEGAADGAHGVGALLVALELHRVPATVTLTLIAAFGWFTSALSTMLAAPLWAGAGLPRWALGLAALAGSLVVAVLLTSLAVRPLAPLFVTRHATSKKDLVGRVCVVSTGRVDERFGQAVIDEGGASHILDVRCDTPGALRRGDRALLVSWDPNAEVFSVEPLDGLLGPPPPLAERLASRVEAPPDGAEDDAIPAARARDEQRRGG
>NC_021658.1|WP_020738311.1|9113442_9114894_-|serine/threonine-protein-kinase
MRTVPVQPGDILAGKYRVERLLGTGNMGVVVAAVHVELGQRVAVKFMRSADDGADGARARFLREARAAVRLRSQHVARVFDVGTLDDGAPYIVMEFLEGRDLAALLRERGPLSLDDAVEYVLQTCEAVGEAHAAGIVHRDLKPANLFVTHDVSGSPCIKVLDFGISKISGADLALTDDDQTLGSPYYMSPEQMISSKDVDARSDLWALGVLLYELIAGQTPFHADSLPEFYGRILAARPTPLRERRSDVPPALDAAIQRCLTHDREQRWRDVAAFAGALAPHAPARARGYPERVSRVLDMQRLSLSGSKDEPGARRAEPSPPPASAGAAEGTAPLPPNSVEETAHTLSPPRSTSSSYELLGAKPRRRALLLFAGALFAGAALAALVGGRQEGAPPPAPTGSPAAALGALDAAPPAPDAPQAPPSTIASHGASATAQAAPTSPSATATAKATRKATKPLPRAKPPAEGPRTPKPEPTFSYDERR
>NC_021658.1|WP_148314059.1|9112340_9113456_-|hypothetical-protein
MSGADIGTRAKGADILRAVRGPGPMRVKRSVIAVSALVLSLSLAPRALADQTAEDRAAADVLFREGRALIKQGRYAPGCSKLAASQKLDPMAGTLLALADCYELNGETASAWATFNDAEAMARKASDPRRSKEAARRAGLLEPQLSRLVIEVAPEARIEGLEVRRNTKLLDAALFGSAIPVNPGEHTIEAAAPGKKAWSAKVLIAPKAGQSTVRVPRLEDAPPPEAAAAPAPARPSRARAAASAAPAASSWSAQKTVGLVLGGVSLAGIAVGAVFGVDTLLKVGEARSQHGCTDDDPPRCDAEGIELHRAANTTANISNVAFAAGGAALIAGLVVFLTAPSSDAAPKAALEVRLQPAVGAGTAGMSLRGSF
>NC_021658.1|WP_020738309.1|9111001_9112339_-|hypothetical-protein
MREMRPGKLVIAGGALLVAGCQLVAGVRTDAELDPEGSGGKGCSAPSDCPGGVCQDGVCKPAEATCVRDLDPFDILTSEDLGGHEVDASSLVLASGPGRVFVSVIDKTASRLVMGTVRELRDPAGPKAEFPLPDGAAFVTGRESGGQVTLLGRVGPDLGQLVFLTTTDGISSEGTFQRFPALAPECSSPNVAASMAFARAGDEVFYAATCEAPGGSTRSLVVGGSAAAAPTLVAQGPRTDASLNVRFYTVTSGRHLLLLDDGATGEAFFRTGAAAADLGVAHQIQFSPSPEEVESFFGAFPLPEGDGVTLLIAHIVPPPRLAVSAEVGVVRDFSSLVEVPPPGFTPVFELQNVSQFNPPGPPMSDGENVYVTLVPHPGKAVNLGWFTRTGESLLPQERIFSLPDGSSAQILGSTVAQLGTKLLVAWIEQHDGATSVRGQRLICAL
>NC_021658.1|WP_020738308.1|9109646_9110090_+|BON-domain-containing-protein
MGGDVGGSRGRPPKGYKRSDERIREDICDQISDHPDLDASDVEVKVQNGEVVLTGTVRERRFKHQLETLAERISGVTDVRNEIRLYREQQQQGEAKAGGLSSSERSTSERSTAGATGAAAGTSGGATSIGATSTSETKNNESRRNAS
>NC_021658.1|WP_020738307.1|9108260_9109571_-|hypothetical-protein
MALSAVAGLLALVPAPLAPAALVVGPLPEAAPGSVAFVLAAAEASLTTEAALAATRSTLATESTLAAAVVALAAIAALAAAESGLTAIAALAAAEAALAAAESSLAAEVALTAVTAPASAEVAIAEVALTAVVAMAALAASESALAAAVAAESTLATEAALAATVAALAAAESALAAAVTALAAAALAAVAALAAAEVTLAAVTALAAAEAALAATEAALAAAVATPGAKIVATSSLEVIAVAARRLALASEIFALGPAAILPTLPAALAALAALAALAALAALAALAALAALAALAAEAALTLVTAAAELPLIPSAAEVLLAASRMALIVSLDDLLVIATMPVASIAGGSALASISLIASLSLVSPKPVLVAPPAVVMFLVDPSLTIRHDSSAFLATRATRQRNRVAPFVVQSTLEGTRDNRDRAAPQARLSVAA
>NC_021658.1|WP_020738306.1|9106951_9107740_-|methyltransferase-domain-containing-protein
MSQQHQSSKDVLDRRTLAGDHRRLAELLRPGQSVLDVGCGTGSITAGIAQAVQPGGEVLGLDRDADLLARAAARFAGRAGLSFACGDVLAFDAEARFDVVTAARALQWVPRLDEALARMVRAARPGGLVVVLDYSHERLRWDPEPPASMRRFYAAFLAWRAGLGMDNALADNLAGRFAAHGLEAVRVTDQDERFRRGDPGFGAALDIWLHVIDGCGPAMISAGALTEREQGEARRDYAGFCRDAAEGLVMVLRAVEGTKPGG
>NC_021658.1|WP_020738319.1|9129310_9129589_+|hypothetical-protein
MTMTELTYRFKGDTPEDITVRLFDIRQVRDAEDPAPWGINVTIAWGAEIAFDRLLAGADPLHAVELACQFASKYIRGRAEDEGGTLDPPISP
>NC_021658.1|WP_020738320.1|9129783_9131955_+|OmpA-family-protein
MKHASLAALSLALTACAGPLAKGPSPDLRLRHVVLYQNGLGYFERTGVMSGERLSLRFREREVDDVLKSMVVVEQDLGPNDTPSTVSALLPRSGQASGPEDPAEVELVFSPAAKRPVSIAYAVPTAAWKATYRVILPAKGQKEKRALLQAWALISNIGDEDWSEVNVTLATGAPLSYASNLRAPAMLDRPELKGVYDGEGGALAPVLAESSPGPDADRDGVFDHEDACPREPGSASPQPNHHGCPKAVRAISSEIQILTAVPFDKGSDVIPPRARPLIEEIARTIKGVPHIRAFEVEGHASTDEAGAADLAARRAAAVRAALLQLGVTAELVTRSHAAEMPLAANDTEDNRQRNRRVSLRASDVGPAQAPSPGREAPAVTPEAMAKVPEGAASVDAVAGAFRYAIANPVTLPKKSSALITLINRSVAGEDVLLFRPDPAAPASATHPFRAAQVENRSALGLQPGSVSIFSGGTFVGEGVLTRLSPGQSATIPYAIDSSTEVRATSMTTDVPVRLVSLSRGALRVEDRYRRVTVYEVRPGRDVPETLLIRHARATGFEPLGLPGCTDATPDACLVEKKLAPGAPQKIVVEETRLSQREIPLVQADSDRLSLYLKGSSVPAELRARLDRALALRRALDAANDELDPLRRRRAELIDRAAELRESLRTIERTPQAGKLRQTLLDRLAEVARQSEELGAKITQRVEDAAMARAELDETLRDLVLEGR
>NC_021658.1|WP_148314061.1|9132181_9134068_+|amidohydrolase-family-protein
MGPGALMRNSSRAAGDSRVPPRRRRASGAAWAASHALFAMQVACGASMPQAADTVLRNGFVYTVDGADSVHQAVAVREGKIVYVGADSGVQGYVGPRTEVVDLKGRMLMPGLVDGHLHAMSGGTQRLLCSLEYKTHTIAQLQAKIQACLDGEPAKGPDQWLEVTSWDRQGTVSVDADPTRAALDALRTQRPILVHSTDHHSALTNSRGMALAGITAKTPDPAGGKIGRDAGGQPTGIFEDAGIALVSAAMPPRTPEDDVRSAKAALDAIRRQGVTTFMDASSDERALRAFTAVQRSGELTARALFAILIDPDEVAKGPEKAIAAAKALASSYDQPAAAPAPGVGARHIKVMLDGVLQAPAQTAAMLAPYHVNVGADGAPQWVPGKHSGDVYFPPDTLKSLLLAAVEAGLDPHVHAIGDRAVRQTLDAYEAVRARLPGNDVRAAIAHCETVDPADFGRFKALGVIPVMSFQWAQEAPYSVDAMKHQLGPERYARLEPEGSLHDAGARLAYGSDWPIDPFAEFLALKIGVTRKGDPTHPASFGPSYAGRLNDDPLLPRNVALRAITMNSAYQLRLEKVVGSIEPGKFADMIVLDQNFLQIPEDDLGKIQVLMTMVGGKIVYTAEAVRPKG
>NC_021658.1|WP_187346055.1|9134134_9135070_+|pseudouridine-5'-phosphate-glycosidase
MKDHLSISSEVRKALAAGRPVVALESTIITHGMPHPQNLGMAQRVEAVVRRSGAVPATIAIMDGKLRVGVKADDLERLAEAGGKAAKASRRDVAALLVSGEVAGTTVATTMMAAAWAGIRVFATGGIGGVHRGAETTFDISADLEELSRTQVAVVCAGAKSILDIPKTLETLETKGVPVLGYKTGDFPAFWARQSGQKVDHRIESAKQAARVIALQFELGLGGVLVANPIPESHALDAREIEARIEEAIQGAEAEGVSRKDLTPFLLKRIVELTGGKSLVANIALVENNAAVAAEIAVALSKLKAKTKAKA
>NC_021658.1|WP_020738324.1|9135066_9135957_+|hypothetical-protein
MSDAGRVLVVGDVMTDVIVRPEGPLVRGSDRRAKIQRRPGGSGANQAVWLGAMGARVSFVARVGASDKPQLEAYFKGFHVDATLAADPREPSGVLVVLVDADGERSFLTDRGANLALEPSDMPLWLLDDTRLVLVSGYSLFAEGPRRAVLWLAGEARSRGIPVAIDAASVGFLREVGAGAFLEWTRGMSTLLANADEAEALSGTGDLAGQMIALGAWFERVIIKRGARGAALGGRRGVRLDEPAPLVDVVDTTGAGDAFAAGFIAAELEGAGEAACLRRGIEAGSRAVTQLGGQPG
>NC_021658.1|WP_020738325.1|9136184_9136616_+|CBS-domain-containing-protein
MKPRKHRRVEDYMSTAVITMKEGDTISAANLEMKLAEIRHIPVVDAKGHVVGIVSDRDVLRHASSLNGKPIPIESIMTRRVRTVQSTTPAADAAQMLLDHKIGCLPVVGDEGQLVGIITETDFLSIAQQALRGIDVTHGAEDR
>NC_021658.1|WP_044986341.1|9136612_9137605_-|alpha/beta-fold-hydrolase
MSKPTPAAEIPRAPTPVLSVSPVVLPAPGRAVDLQVRVSAPVTGSELPILLLSHGHGPSNHLSSLNGYAPLANYFAAHGFVVIQPTHLDSKTLPFRDSDHPEAPLYWRSRAEDMKRILDQLDAIEGAVAVLAGRLDRSKVAVVGHSMGGHTASVLLGARLRDPHDGTEVNLAEPRIKAGVLLAAPGRGGDALSELAAKKYPIFSTIDFSTMTAPALVIAGDKDASPHLTVAGADWHADPYFLSPGPKSLVTLFDAGHGLGGVSGYDVAETTDENPERVAAVQRLTWAYLRAELYPGDPAWQEAQNALTGAASPLGRVESKKFWARLPTVL
>NC_021658.1|WP_063752049.1|9137889_9138672_+|helix-turn-helix-transcriptional-regulator
MGSAASTFSLSRFVEEVRAVAPVAGRALDVEWLPNGRTTLVFRVIEEGRRGDVAVAGPRTRALFKNATGVARAVMLQFKPGWSGPLLGVAANALTDQIVPLEDIWGRSGGDLCLDLLAARSLPEVLDRLSHAIALRTRETSEPASARLARRAVLLLEGGEVRVERVAERLGVTARHLRRAFTESVGIGPKDFARTVRLQRAVRRAASSKDGARIAADAGYYDQAHLIADFRELVGLTPGAFLKRAGARGGEAMAGGAPSR
>NC_021658.1|WP_049949696.1|9138712_9139288_-|hypothetical-protein
MNSFTKRHRFAFSVLLLCAPLLAGANDDGCGQAVPELDGVDSAPAELVSAAAGGIKPGRCRPTGCSGQVCADQTVYTTCEWREEYACYGDYGICERDASGQCGWRQTPELTACLDGGGVLEAAPGGGPGPCVVTGCSGQVCADDDVLTTCEWREEYACYGKHGVCERDASGQCGWRDTPELDACLESASGI
>NC_021658.1|WP_080682400.1|9139806_9141603_+|hypothetical-protein
MTPSKFRRVGPGMLRRGWAAGVALLLASAPASGGMSKLWGAAGEAWTPTSRLPDYSHAGYRAGEAPLPEVPVVANVTDFGAVGDGVTDDTDAFAAAIAAAEDGAVLIPAGRYVITDVLRISKSNVVLRGEGSGPDGSVLFIPQSLADVYGPSPSWSWSGAFIDIRPSQEVVATTATAVMTAAPRGDTSLTVASTAGLAEGQLVELHQVDDGSGSLGRHLHNDQAEAGDCPYMVPLTLDSPLRVRSIDGGVVTFTQPLRTDVSLAWSPELQTHEVVEEVGVEHLRIEFIEVPYAGHLKEPGYNAITFTAAADSWVRDVTIVDADSGIFTGPYVKGLTFQDIALEGRQGHHGIALSYSADILVRDFDIANAWTHSLTVSARASGNVFSRGTGAELLVLDHHGDSPFENLFTQLGAYTFAGSGGEECTGPHGGARNTYWNLEAPMYVPLLWGHVQSNVVGEGVVVADALTEDAQWYETVSALEPANLYEAQASRRLCGEFSSACNLGVYEPDTASCSQAPRPRGTACDDGDPDTDGDACSEGVCAGTSSSGCSYRPAAPGRGSSPLVLGLLLAISAAAAFPRLRLDRKHLAHVLKRWSRLQ

Crispr_ID: NC_021658_35

• CRISPR_ID: NC_021658_35
• CRISPR_location: 9128341-9128665
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NC_021658_35

Consensus_repeat	Method
GGCGGCGCCGGCGGCAACGGCGGC	CRISPRCasFinder

spacers of NC_021658_35

>35.1|9128365|27|NC_021658|CRISPRCasFinder
AACGGCGGTCCCGAGGGGGAGCACGCG
>35.2|9128416|60|NC_021658|CRISPRCasFinder
GGCGGGTCGCTCGGCGGGAACGGGGGCGCGCCGGGGAACAACACGAATCGCGCGCAGGCG
>35.3|9128500|18|NC_021658|CRISPRCasFinder
AACGGCGGGGTCGGGCTG
>35.4|9128542|60|NC_021658|CRISPRCasFinder
ACGATCACGGGCAACCTCTGGCGGGCGAGGGCGGGCAACACCGGCGGAGCGGGCCTGCCC
>35.5|9128626|15|NC_021658|CRISPRCasFinder
GGCGGCGGCGGGGCC

CRISPR arrays and Neighbor proteins around NC_021658_35

CRISPR arrays

The CRISPR arrays of NC_021658_35

>merge|NC_021658|35|9128341-9128665|CRISPRCasFinder
AGCCGCACGGGCGGCAACGGGGGCAACGGCGGTCCCGAGGGGGAGCACGCGGGCAGCGGCGGCCAGAACGGCGTGGGCGGGTCGCTCGGCGGGAACGGGGGCGCGCCGGGGAACAACACGAATCGCGCGCAGGCGGGCACCGCCGGCCAGAACGGCGCGAACGGCGGGGTCGGGCTGAACGGCACCGGCGGCAACGGCGGGACGATCACGGGCAACCTCTGGCGGGCGAGGGCGGGCAACACCGGCGGAGCGGGCCTGCCCGGCAACGGGGCCGGCGGCGGCGGCGGCGGCGGCGGGGCCGGGGGCTGCGGCGGCCTCGGAGGCG

>NC_021658|35|31|9128341-9128665|CRISPRCasFinder
AGCCGCACGGGCGGCAACGGGGGC	AACGGCGGTCCCGAGGGGGAGCACGCG
GGCAGCGGCGGCCAGAACGGCGTG	GGCGGGTCGCTCGGCGGGAACGGGGGCGCGCCGGGGAACAACACGAATCGCGCGCAGGCG
GGCACCGCCGGCCAGAACGGCGCG	AACGGCGGGGTCGGGCTG
AACGGCACCGGCGGCAACGGCGGG	ACGATCACGGGCAACCTCTGGCGGGCGAGGGCGGGCAACACCGGCGGAGCGGGCCTGCCC
GGCAACGGGGCCGGCGGCGGCGGC	GGCGGCGGCGGGGCC
GGGGGCTGCGGCGGCCTCGGAGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_044986336.1|9119507_9120899_-|hypothetical-protein	unknown	unknown	gnl|CDD|366454
NC_021658.1|WP_020738313.1|9115979_9116828_+|DUF1449-family-protein	unknown	unknown	unknown
NC_021658.1|WP_020738325.1|9136184_9136616_+|CBS-domain-containing-protein	unknown	unknown	gnl|CDD|341361
NC_021658.1|WP_020738307.1|9108260_9109571_-|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NC_021658.1|WP_044986337.1|9121307_9122918_-|DUF1552-domain-containing-protein	unknown	unknown	gnl|CDD|377875
NC_021658.1|WP_187345680.1|9116979_9119202_+|hypothetical-protein	unknown	unknown	gnl|CDD|225177
NC_021658.1|WP_020738308.1|9109646_9110090_+|BON-domain-containing-protein	unknown	unknown	gnl|CDD|335963
NC_021658.1|WP_020738306.1|9106951_9107740_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|181382
NC_021658.1|WP_020738324.1|9135066_9135957_+|hypothetical-protein	unknown	unknown	gnl|CDD|238571
NC_021658.1|WP_063752049.1|9137889_9138672_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197666
NC_021658.1|WP_020738311.1|9113442_9114894_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_044986341.1|9136612_9137605_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|226651
NC_021658.1|WP_080682400.1|9139806_9141603_+|hypothetical-protein	unknown	unknown	gnl|CDD|378931
NC_021658.1|WP_148314059.1|9112340_9113456_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738320.1|9129783_9131955_+|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NC_021658.1|WP_187346055.1|9134134_9135070_+|pseudouridine-5'-phosphate-glycosidase	unknown	unknown	gnl|CDD|377251
NC_021658.1|WP_020738309.1|9111001_9112339_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738319.1|9129310_9129589_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314061.1|9132181_9134068_+|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|224490
NC_021658.1|WP_049949696.1|9138712_9139288_-|hypothetical-protein	unknown	unknown	gnl|CDD|275110

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_044986336.1|9119507_9120899_-|hypothetical-protein	gnl|CDD|366454	pfam01082, Cu2_monooxygen, Copper type II ascorbate-dependent monooxygenase, N-terminal domain. The N and C-terminal domains of members of this family adopt the same PNGase F-like fold.	2.09674e-09
NC_021658.1|WP_020738325.1|9136184_9136616_+|CBS-domain-containing-protein	gnl|CDD|341361	cd04584, CBS_pair_AcuB_like, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the ACT domain. The putative Acetoin Utilization Protein (Acub) from Vibrio Cholerae contains a CBS pair domain. The acetoin utilization protein plays a role in growth and sporulation on acetoin or butanediol for use as a carbon source. Acetoin is an important physiological metabolite excreted by many microorganisms. It is used as an external energy store by a number of fermentive bacteria. Acetoin is produced by the decarboxylation of alpha-acetolactate. Once superior carbon sources are exhausted, and the culture enters stationary phase, acetoin can be utilised in order to maintain the culture density. The conversion of acetoin into acetyl-CoA or 2,3-butanediol is catalysed by the acetoin dehydrogenase complex and acetoin reductase/2,3-butanediol dehydrogenase, respectively. Acetoin utilization proteins, acetylpolyamine amidohydrolases, and histone deacetylases are members of an ancient protein superfamily.This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the acetoin utilization proteins in bacteria. Acetoin is a product of fermentative metabolism in many prokaryotic and eukaryotic microorganisms. They produce acetoin as an external carbon storage compound and then later reuse it as a carbon and energy source during their stationary phase and sporulation. In addition these CBS domains are associated with a downstream ACT (aspartate kinase/chorismate mutase/TyrA) domain, which is linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. Pairs of ACT domains bind specifically to a particular amino acid leading to regulation of the linked enzyme. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	5.92812e-44
NC_021658.1|WP_020738307.1|9108260_9109571_-|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	8.21312e-05
NC_021658.1|WP_044986337.1|9121307_9122918_-|DUF1552-domain-containing-protein	gnl|CDD|377875	pfam07586, HXXSHH, Protein of unknown function (DUF1552). A family of proteins identified in Rhodopirellula baltica.	1.14405e-73
NC_021658.1|WP_187345680.1|9116979_9119202_+|hypothetical-protein	gnl|CDD|225177	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown].	3.16434e-44
NC_021658.1|WP_020738308.1|9109646_9110090_+|BON-domain-containing-protein	gnl|CDD|335963	pfam04972, BON, BON domain. This domain is found in a family of osmotic shock protection proteins. It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes.	4.65001e-15
NC_021658.1|WP_020738306.1|9106951_9107740_-|methyltransferase-domain-containing-protein	gnl|CDD|181382	PRK08317, PRK08317, hypothetical protein; Provisional.	3.71565e-25
NC_021658.1|WP_020738324.1|9135066_9135957_+|hypothetical-protein	gnl|CDD|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	1.35205e-46
NC_021658.1|WP_063752049.1|9137889_9138672_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	8.48858e-18
NC_021658.1|WP_020738311.1|9113442_9114894_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.45779e-98
NC_021658.1|WP_080682400.1|9139806_9141603_+|hypothetical-protein	gnl|CDD|378931	pfam12708, Pectate_lyase_3, Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.	4.44349e-14
NC_021658.1|WP_020738320.1|9129783_9131955_+|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	2.67797e-23
NC_021658.1|WP_187346055.1|9134134_9135070_+|pseudouridine-5'-phosphate-glycosidase	gnl|CDD|377251	pfam04227, Indigoidine_A, Indigoidine synthase A like protein. Indigoidine is a blue pigment synthesized by Erwinia chrysanthemi implicated in pathogenicity and protection from oxidative stress. IdgA is involved in indigoidine biosynthesis, but its specific function is unknown. The recommended name for this protein is now pseudouridine-5'-phosphate glycosidase.	1.32873e-175
NC_021658.1|WP_044986341.1|9136612_9137605_-|alpha/beta-fold-hydrolase	gnl|CDD|226651	COG4188, COG4188, Predicted dienelactone hydrolase [General function prediction only].	1.01729e-21
NC_021658.1|WP_148314061.1|9132181_9134068_+|amidohydrolase-family-protein	gnl|CDD|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	4.2029e-129
NC_021658.1|WP_049949696.1|9138712_9139288_-|hypothetical-protein	gnl|CDD|275110	TIGR04292, hypothetical_protein_PF0600, heavy-Cys/CGP-CTERM domain protein. Members of this protein family are restricted to the Pyrococcus and Thermococcus genera of the archaea. Member proteins have a C-terminal, Cys-containing predicted surface anchor domain, where the Cys may be the site of cleavage and lipid attachment (see domain TIGR04288). Members also contain a region crowded with 10 invariant Cys in 60 residues (see domain TIGR04289), possible ligands to some redox cofactor. Note that a sorting motif is CGP. Previously, the motif was named incorrectly as GCP-CTERM in this model due to a typographical error.	0.000140364

Protein sequences

>NC_021658.1|WP_044986337.1|9121307_9122918_-|DUF1552-domain-containing-protein
MNRRLFLRGIGGAALAVPFLNSLVRSARAQEVPSPRRLVIFYTNNGCLTNRWFPTIENGSGSVTAASLEAVQADGKPRTLAPLAPFAAKLLFPRGLAMPLNGFNNKVDGVVHFDPHDQGMGSKLTCAPLDPAGEHWALSHSLDHEIAQRFNQGTNKSPLVLSVGNAFTNVKGIVSYSASKTPYAPVTNARTVYSSLTGLFASGAETEADHRVKRGESIIDLVSADLGAFKARKMSAPDRRKVDDWLSLLRETEQQVVPSACTAEAAAALGVTDAALTEAGYPSRGGGFPNSEKVYTLGSEMMIRLIALTMMCDSNRSIVLQWPGYVTFNWDGIAHTHDHHGLSHRNGSAATGGQCVSGVIEQIHEIDRWYAGRYAKLVKTIDSIEEGDGTMLDNSAVMWLPELADGNAHNNNNLPIVIAGSAGGYLKQGVSVNVAGGNLAVGNSEASCATGAEGEDNSGNTGSSGGTVPLNKLFTTLINALGAGMPDWEPVDRFGVSDAVSAGFGGSAPSFTTDGAGKVIDGPGISNPGELDAIKA
>NC_021658.1|WP_044986336.1|9119507_9120899_-|hypothetical-protein
MRKSMSFVLTPLAFLPALLLGCSGEEAPGSAGTSPTFHRDVEPLLQKHCMSCHSPGNIAPFGLTTYEEARTVAGLMAHATRERTMPPWGAEETDECQPPYGWKDDLRLSEAEIAVLEAWSAAGSPEGDPADAPPPFVPGAGGLSGVELEVAPEEPFVASGDADQFRCFVMDPGLTETRYINGVHIVPGNSKVVHHALVFLDREGASDELADEHGGYDCFGGPGFSGELVAAWAPGSVPLEFEPNIGAELPAGARLVMQVHYHPAGTTADPDTTRLQMRFTKGVPEYSMGVALIGNFETSADEGGGLLPGPNDGDGAEFLIPAGAEDHVETMQFRMPESVSDAEMYLYGAGTHMHYVGTDMKVTLEHTRGDPDNASKQCLVQTPRWDFSWQRGFYYDAPIAELPRIHGGDLLTMRCTYNNSNSNPFLVKALQEQNMPGPVDVHLGESTLDEMCLAALIYVTKRQ
>NC_021658.1|WP_187345680.1|9116979_9119202_+|hypothetical-protein
MPTVTVPLILVLVGVLAFVALGMLVMYAKFYRQVDQGKALIINTRGQDPIVTFTGTLVLPIIHRAEYMDISVKTIEIDRRGKEGLICKDNIRADIKVTFFVQVNKTQDDVRTVARTIGCVRASNPETLEQLFAAKFSEALKTVGKRLNFEDLYKERQKFKDDIIDVIGKDLSGFVLADAAIDYLEQTPIELLDKDNIMDAEGIRKITELTVAQNVLTNELRQKERMEIGSQNLNSDEAIFRFEQRRAEAEAKKAKEIAVAQAREQNEAARITSDERKKTVLLQEKNDEEAFVAREAKERGVQVAQKNKEREVAVETERVAKARELEIVSRERDVSLQQIAREKELELQKKDIADVVRARIAVEKTVAEEEERIKDVRAVAEATRLKDVTRINAEAEAQEQLVKQIKGAEASEEAAKFRAREKLLIADAELEASDKAARAKIRMAEGVQAESAADGLARIRVKEADAQAIEKQGFAEARVALEKMNAAAVGEEKQGLARVLVKEAEAQAIEKQGRAEALVARERLLAEAAGIEQKGLAAARTREAEALALEKTGLAEATAIKQRLLAEAAGTAEKAAAMKALDGVGREHEEFRLRLEKERAVELEALRIRADIARAQAEILRGAFEQAKINIVGGDGAFFDRFVKAVTLGQSVDGMVDQSATVRALVGDYLNGNASLPEDLKQLVAPPSPLARSADGTLSGMLTSLLPSADADGKKKIEALAQKARELGLDQLAQQRTPRT
>NC_021658.1|WP_020738313.1|9115979_9116828_+|DUF1449-family-protein
MAEVLAASLAFPAVIFTVLLALALIYWLFVVLGALDLDLLGGAHGDATPDLGGLEGAAKGALEGAAKGSLEGAAKGSLEGAADGAHGVGALLVALELHRVPATVTLTLIAAFGWFTSALSTMLAAPLWAGAGLPRWALGLAALAGSLVVAVLLTSLAVRPLAPLFVTRHATSKKDLVGRVCVVSTGRVDERFGQAVIDEGGASHILDVRCDTPGALRRGDRALLVSWDPNAEVFSVEPLDGLLGPPPPLAERLASRVEAPPDGAEDDAIPAARARDEQRRGG
>NC_021658.1|WP_020738311.1|9113442_9114894_-|serine/threonine-protein-kinase
MRTVPVQPGDILAGKYRVERLLGTGNMGVVVAAVHVELGQRVAVKFMRSADDGADGARARFLREARAAVRLRSQHVARVFDVGTLDDGAPYIVMEFLEGRDLAALLRERGPLSLDDAVEYVLQTCEAVGEAHAAGIVHRDLKPANLFVTHDVSGSPCIKVLDFGISKISGADLALTDDDQTLGSPYYMSPEQMISSKDVDARSDLWALGVLLYELIAGQTPFHADSLPEFYGRILAARPTPLRERRSDVPPALDAAIQRCLTHDREQRWRDVAAFAGALAPHAPARARGYPERVSRVLDMQRLSLSGSKDEPGARRAEPSPPPASAGAAEGTAPLPPNSVEETAHTLSPPRSTSSSYELLGAKPRRRALLLFAGALFAGAALAALVGGRQEGAPPPAPTGSPAAALGALDAAPPAPDAPQAPPSTIASHGASATAQAAPTSPSATATAKATRKATKPLPRAKPPAEGPRTPKPEPTFSYDERR
>NC_021658.1|WP_148314059.1|9112340_9113456_-|hypothetical-protein
MSGADIGTRAKGADILRAVRGPGPMRVKRSVIAVSALVLSLSLAPRALADQTAEDRAAADVLFREGRALIKQGRYAPGCSKLAASQKLDPMAGTLLALADCYELNGETASAWATFNDAEAMARKASDPRRSKEAARRAGLLEPQLSRLVIEVAPEARIEGLEVRRNTKLLDAALFGSAIPVNPGEHTIEAAAPGKKAWSAKVLIAPKAGQSTVRVPRLEDAPPPEAAAAPAPARPSRARAAASAAPAASSWSAQKTVGLVLGGVSLAGIAVGAVFGVDTLLKVGEARSQHGCTDDDPPRCDAEGIELHRAANTTANISNVAFAAGGAALIAGLVVFLTAPSSDAAPKAALEVRLQPAVGAGTAGMSLRGSF
>NC_021658.1|WP_020738309.1|9111001_9112339_-|hypothetical-protein
MREMRPGKLVIAGGALLVAGCQLVAGVRTDAELDPEGSGGKGCSAPSDCPGGVCQDGVCKPAEATCVRDLDPFDILTSEDLGGHEVDASSLVLASGPGRVFVSVIDKTASRLVMGTVRELRDPAGPKAEFPLPDGAAFVTGRESGGQVTLLGRVGPDLGQLVFLTTTDGISSEGTFQRFPALAPECSSPNVAASMAFARAGDEVFYAATCEAPGGSTRSLVVGGSAAAAPTLVAQGPRTDASLNVRFYTVTSGRHLLLLDDGATGEAFFRTGAAAADLGVAHQIQFSPSPEEVESFFGAFPLPEGDGVTLLIAHIVPPPRLAVSAEVGVVRDFSSLVEVPPPGFTPVFELQNVSQFNPPGPPMSDGENVYVTLVPHPGKAVNLGWFTRTGESLLPQERIFSLPDGSSAQILGSTVAQLGTKLLVAWIEQHDGATSVRGQRLICAL
>NC_021658.1|WP_020738308.1|9109646_9110090_+|BON-domain-containing-protein
MGGDVGGSRGRPPKGYKRSDERIREDICDQISDHPDLDASDVEVKVQNGEVVLTGTVRERRFKHQLETLAERISGVTDVRNEIRLYREQQQQGEAKAGGLSSSERSTSERSTAGATGAAAGTSGGATSIGATSTSETKNNESRRNAS
>NC_021658.1|WP_020738307.1|9108260_9109571_-|hypothetical-protein
MALSAVAGLLALVPAPLAPAALVVGPLPEAAPGSVAFVLAAAEASLTTEAALAATRSTLATESTLAAAVVALAAIAALAAAESGLTAIAALAAAEAALAAAESSLAAEVALTAVTAPASAEVAIAEVALTAVVAMAALAASESALAAAVAAESTLATEAALAATVAALAAAESALAAAVTALAAAALAAVAALAAAEVTLAAVTALAAAEAALAATEAALAAAVATPGAKIVATSSLEVIAVAARRLALASEIFALGPAAILPTLPAALAALAALAALAALAALAALAALAALAALAAEAALTLVTAAAELPLIPSAAEVLLAASRMALIVSLDDLLVIATMPVASIAGGSALASISLIASLSLVSPKPVLVAPPAVVMFLVDPSLTIRHDSSAFLATRATRQRNRVAPFVVQSTLEGTRDNRDRAAPQARLSVAA
>NC_021658.1|WP_020738306.1|9106951_9107740_-|methyltransferase-domain-containing-protein
MSQQHQSSKDVLDRRTLAGDHRRLAELLRPGQSVLDVGCGTGSITAGIAQAVQPGGEVLGLDRDADLLARAAARFAGRAGLSFACGDVLAFDAEARFDVVTAARALQWVPRLDEALARMVRAARPGGLVVVLDYSHERLRWDPEPPASMRRFYAAFLAWRAGLGMDNALADNLAGRFAAHGLEAVRVTDQDERFRRGDPGFGAALDIWLHVIDGCGPAMISAGALTEREQGEARRDYAGFCRDAAEGLVMVLRAVEGTKPGG
>NC_021658.1|WP_020738319.1|9129310_9129589_+|hypothetical-protein
MTMTELTYRFKGDTPEDITVRLFDIRQVRDAEDPAPWGINVTIAWGAEIAFDRLLAGADPLHAVELACQFASKYIRGRAEDEGGTLDPPISP
>NC_021658.1|WP_020738320.1|9129783_9131955_+|OmpA-family-protein
MKHASLAALSLALTACAGPLAKGPSPDLRLRHVVLYQNGLGYFERTGVMSGERLSLRFREREVDDVLKSMVVVEQDLGPNDTPSTVSALLPRSGQASGPEDPAEVELVFSPAAKRPVSIAYAVPTAAWKATYRVILPAKGQKEKRALLQAWALISNIGDEDWSEVNVTLATGAPLSYASNLRAPAMLDRPELKGVYDGEGGALAPVLAESSPGPDADRDGVFDHEDACPREPGSASPQPNHHGCPKAVRAISSEIQILTAVPFDKGSDVIPPRARPLIEEIARTIKGVPHIRAFEVEGHASTDEAGAADLAARRAAAVRAALLQLGVTAELVTRSHAAEMPLAANDTEDNRQRNRRVSLRASDVGPAQAPSPGREAPAVTPEAMAKVPEGAASVDAVAGAFRYAIANPVTLPKKSSALITLINRSVAGEDVLLFRPDPAAPASATHPFRAAQVENRSALGLQPGSVSIFSGGTFVGEGVLTRLSPGQSATIPYAIDSSTEVRATSMTTDVPVRLVSLSRGALRVEDRYRRVTVYEVRPGRDVPETLLIRHARATGFEPLGLPGCTDATPDACLVEKKLAPGAPQKIVVEETRLSQREIPLVQADSDRLSLYLKGSSVPAELRARLDRALALRRALDAANDELDPLRRRRAELIDRAAELRESLRTIERTPQAGKLRQTLLDRLAEVARQSEELGAKITQRVEDAAMARAELDETLRDLVLEGR
>NC_021658.1|WP_148314061.1|9132181_9134068_+|amidohydrolase-family-protein
MGPGALMRNSSRAAGDSRVPPRRRRASGAAWAASHALFAMQVACGASMPQAADTVLRNGFVYTVDGADSVHQAVAVREGKIVYVGADSGVQGYVGPRTEVVDLKGRMLMPGLVDGHLHAMSGGTQRLLCSLEYKTHTIAQLQAKIQACLDGEPAKGPDQWLEVTSWDRQGTVSVDADPTRAALDALRTQRPILVHSTDHHSALTNSRGMALAGITAKTPDPAGGKIGRDAGGQPTGIFEDAGIALVSAAMPPRTPEDDVRSAKAALDAIRRQGVTTFMDASSDERALRAFTAVQRSGELTARALFAILIDPDEVAKGPEKAIAAAKALASSYDQPAAAPAPGVGARHIKVMLDGVLQAPAQTAAMLAPYHVNVGADGAPQWVPGKHSGDVYFPPDTLKSLLLAAVEAGLDPHVHAIGDRAVRQTLDAYEAVRARLPGNDVRAAIAHCETVDPADFGRFKALGVIPVMSFQWAQEAPYSVDAMKHQLGPERYARLEPEGSLHDAGARLAYGSDWPIDPFAEFLALKIGVTRKGDPTHPASFGPSYAGRLNDDPLLPRNVALRAITMNSAYQLRLEKVVGSIEPGKFADMIVLDQNFLQIPEDDLGKIQVLMTMVGGKIVYTAEAVRPKG
>NC_021658.1|WP_187346055.1|9134134_9135070_+|pseudouridine-5'-phosphate-glycosidase
MKDHLSISSEVRKALAAGRPVVALESTIITHGMPHPQNLGMAQRVEAVVRRSGAVPATIAIMDGKLRVGVKADDLERLAEAGGKAAKASRRDVAALLVSGEVAGTTVATTMMAAAWAGIRVFATGGIGGVHRGAETTFDISADLEELSRTQVAVVCAGAKSILDIPKTLETLETKGVPVLGYKTGDFPAFWARQSGQKVDHRIESAKQAARVIALQFELGLGGVLVANPIPESHALDAREIEARIEEAIQGAEAEGVSRKDLTPFLLKRIVELTGGKSLVANIALVENNAAVAAEIAVALSKLKAKTKAKA
>NC_021658.1|WP_020738324.1|9135066_9135957_+|hypothetical-protein
MSDAGRVLVVGDVMTDVIVRPEGPLVRGSDRRAKIQRRPGGSGANQAVWLGAMGARVSFVARVGASDKPQLEAYFKGFHVDATLAADPREPSGVLVVLVDADGERSFLTDRGANLALEPSDMPLWLLDDTRLVLVSGYSLFAEGPRRAVLWLAGEARSRGIPVAIDAASVGFLREVGAGAFLEWTRGMSTLLANADEAEALSGTGDLAGQMIALGAWFERVIIKRGARGAALGGRRGVRLDEPAPLVDVVDTTGAGDAFAAGFIAAELEGAGEAACLRRGIEAGSRAVTQLGGQPG
>NC_021658.1|WP_020738325.1|9136184_9136616_+|CBS-domain-containing-protein
MKPRKHRRVEDYMSTAVITMKEGDTISAANLEMKLAEIRHIPVVDAKGHVVGIVSDRDVLRHASSLNGKPIPIESIMTRRVRTVQSTTPAADAAQMLLDHKIGCLPVVGDEGQLVGIITETDFLSIAQQALRGIDVTHGAEDR
>NC_021658.1|WP_044986341.1|9136612_9137605_-|alpha/beta-fold-hydrolase
MSKPTPAAEIPRAPTPVLSVSPVVLPAPGRAVDLQVRVSAPVTGSELPILLLSHGHGPSNHLSSLNGYAPLANYFAAHGFVVIQPTHLDSKTLPFRDSDHPEAPLYWRSRAEDMKRILDQLDAIEGAVAVLAGRLDRSKVAVVGHSMGGHTASVLLGARLRDPHDGTEVNLAEPRIKAGVLLAAPGRGGDALSELAAKKYPIFSTIDFSTMTAPALVIAGDKDASPHLTVAGADWHADPYFLSPGPKSLVTLFDAGHGLGGVSGYDVAETTDENPERVAAVQRLTWAYLRAELYPGDPAWQEAQNALTGAASPLGRVESKKFWARLPTVL
>NC_021658.1|WP_063752049.1|9137889_9138672_+|helix-turn-helix-transcriptional-regulator
MGSAASTFSLSRFVEEVRAVAPVAGRALDVEWLPNGRTTLVFRVIEEGRRGDVAVAGPRTRALFKNATGVARAVMLQFKPGWSGPLLGVAANALTDQIVPLEDIWGRSGGDLCLDLLAARSLPEVLDRLSHAIALRTRETSEPASARLARRAVLLLEGGEVRVERVAERLGVTARHLRRAFTESVGIGPKDFARTVRLQRAVRRAASSKDGARIAADAGYYDQAHLIADFRELVGLTPGAFLKRAGARGGEAMAGGAPSR
>NC_021658.1|WP_049949696.1|9138712_9139288_-|hypothetical-protein
MNSFTKRHRFAFSVLLLCAPLLAGANDDGCGQAVPELDGVDSAPAELVSAAAGGIKPGRCRPTGCSGQVCADQTVYTTCEWREEYACYGDYGICERDASGQCGWRQTPELTACLDGGGVLEAAPGGGPGPCVVTGCSGQVCADDDVLTTCEWREEYACYGKHGVCERDASGQCGWRDTPELDACLESASGI
>NC_021658.1|WP_080682400.1|9139806_9141603_+|hypothetical-protein
MTPSKFRRVGPGMLRRGWAAGVALLLASAPASGGMSKLWGAAGEAWTPTSRLPDYSHAGYRAGEAPLPEVPVVANVTDFGAVGDGVTDDTDAFAAAIAAAEDGAVLIPAGRYVITDVLRISKSNVVLRGEGSGPDGSVLFIPQSLADVYGPSPSWSWSGAFIDIRPSQEVVATTATAVMTAAPRGDTSLTVASTAGLAEGQLVELHQVDDGSGSLGRHLHNDQAEAGDCPYMVPLTLDSPLRVRSIDGGVVTFTQPLRTDVSLAWSPELQTHEVVEEVGVEHLRIEFIEVPYAGHLKEPGYNAITFTAAADSWVRDVTIVDADSGIFTGPYVKGLTFQDIALEGRQGHHGIALSYSADILVRDFDIANAWTHSLTVSARASGNVFSRGTGAELLVLDHHGDSPFENLFTQLGAYTFAGSGGEECTGPHGGARNTYWNLEAPMYVPLLWGHVQSNVVGEGVVVADALTEDAQWYETVSALEPANLYEAQASRRLCGEFSSACNLGVYEPDTASCSQAPRPRGTACDDGDPDTDGDACSEGVCAGTSSSGCSYRPAAPGRGSSPLVLGLLLAISAAAAFPRLRLDRKHLAHVLKRWSRLQ

Crispr_ID: NC_021658_37

• CRISPR_ID: NC_021658_37
• CRISPR_location: 9167757-9170662
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 39 spacers

Consensus repeat of NC_021658_37

Consensus_repeat	Method
TCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	PILER-CR
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CRISPRCasFinder
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CRT
CTCTCCGCCGCTGAAAGGCGGCGGCCCCATTGAAGC	PILER-CR

spacers of NC_021658_37

>37.1|9167792|36|NC_021658|PILER-CR
GCCGGCCTCGTCGCTTCTCATCCCCTCTCGGGTGAG
>37.2|9167863|66|NC_021658|PILER-CR
GTCGGGCAAGAGAGCCTCCGCCCACGTCCTGACGTCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
>37.3|9167964|37|NC_021658|PILER-CR
GGTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
>37.4|9168036|38|NC_021658|PILER-CR
GTGTTGGTGAACACAACCTTAGCCAACTCGCTCATGTT
>37.5|9168109|40|NC_021658|PILER-CR
TCGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
>37.6|9168184|37|NC_021658|PILER-CR
GGTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
>37.7|9167793|35|NC_021658|CRISPRCasFinder,CRT
CCGGCCTCGTCGCTTCTCATCCCCTCTCGGGTGAG
>37.8|9167864|65|NC_021658|CRISPRCasFinder,CRT
TCGGGCAAGAGAGCCTCCGCCCACGTCCTGACGTCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
>37.9|9167965|36|NC_021658|CRISPRCasFinder,CRT
GTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
>37.10|9168037|37|NC_021658|CRISPRCasFinder,CRT
TGTTGGTGAACACAACCTTAGCCAACTCGCTCATGTT
>37.11|9168110|39|NC_021658|CRISPRCasFinder,CRT
CGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
>37.12|9168185|36|NC_021658|CRISPRCasFinder,CRT
GTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
>37.13|9168257|37|NC_021658|CRISPRCasFinder,CRT
TCAAACACACCTCTCCGACCGTGCTGTTCGCAGAGCG
>37.14|9168330|39|NC_021658|CRISPRCasFinder,CRT
CGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
>37.15|9168405|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TTGGCGCGGACCGTTGCGGCGCGCGCCGGACCCCCTG
>37.16|9168478|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGAGGCAGAGGAGCGGATGTTTAACACCGGAGACTT
>37.17|9168550|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
AGAGCGCCGAGGCGCGCGGGAGGATGGAGATGAGCAT
>37.18|9168623|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CTCCGAGGCAACCAGCGCATCGGCCGCGCACGTGAG
>37.19|9168695|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGCGGCGCAGACGGCGCCGGAGCAGACGATCGCGGA
>37.20|9168767|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
AAGATCGTCGAGGCCACTGGCAACGTTCGCCAGGTCTA
>37.21|9168841|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TAGAAGGCGGGCCGGAACCCTCGCACGTGGTCGGCGTA
>37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CACGTTCCTGATCACGACGACGAAGATGCTCATCAG
>37.23|9168987|39|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GCCCTGCTACAACGTAGAGCTTGAAGACCCGGACCGTAT
>37.24|9169062|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GTCTCCCCGACGACCCTCACGCCGGGCGTCTACCT
>37.25|9169133|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ACCGCGTCGTCGTACACGCTCTCCGGCAGATCGAA
>37.26|9169204|40|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGTGCGTGCCGTTCGCACGGACGCGCCGGATTTTGTCCGG
>37.27|9169280|39|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CTCGATGGCGCGCCCCGAGGCGTCGCAGCCCTCCTGGCC
>37.28|9169355|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GCGGGAGTTCGACCGGCTCCGCGGCGACGCGAAGGC
>37.29|9169427|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CCGCCGGTCGTCGTGGTCGGCGGCGCGCGCGTGCCA
>37.30|9169499|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GGCCCAGTGGATGGATAATAGCGGCATGTTCCGCAA
>37.31|9169571|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGCATAGGCACTGCTGCGACGTCAGGAACGTGCACCT
>37.32|9169644|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GATGCAGGGATTTTTCGTCCCTCCTACGCATGCCATC
>37.33|9169717|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CCAGCAAGGCTCCGGCATCGAACACGACCTTAGAG
>37.34|9169788|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGCGTTCGGACGCGATGCCTCGATGTCGCGGCTGTT
>37.35|9169860|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CCACCTCGCAGACACGTGGGAGGTCATCTGCAAGAC
>37.36|9169932|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TCGTGCAGGTCGACTTGACGGTGCGCCCGACGGAGCG
>37.37|9170005|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CTGCGCAGCGAGTCCGCGCGCGACGCGTTCGTCGAGGT
>37.38|9170079|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
ATGGAAGCGAGATGAGCTGTGGTTCACATTTGCGGA
>37.39|9170151|41|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CTCAAGGAAACAGGGCGCACGGGGAGCTCCCCGAACTTGCA
>37.40|9170228|37|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CGCGCGGCAGGGCCATTACGCAGCGCTCCCCTCTCCG
>37.41|9170301|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GTGCTCTCAGCCCAGTCGCGCACGCTCTCCGCGGT
>37.42|9170372|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TCAGCGTCGACGGGACGTCGCCGAGCAGGGCGAGC
>37.43|9170443|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
CACACGCGCTGTGCGAACCGGTCGATCGCGTACCTCGT
>37.44|9170517|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR
TGGGTGAGCCAGTCAGCGAAGAGTATACGTGCACTT
>37.45|9170589|38|NC_021658|CRISPRCasFinder,CRT,PILER-CR
GCGGTTTTCGCTGTGCCGGAACCGGAGCCACTCTGGAT

CRISPR arrays and Neighbor proteins around NC_021658_37

CRISPR arrays

The CRISPR arrays of NC_021658_37

>merge|NC_021658|37|9167757-9170662|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GCTTCCATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCCGGCCTCGTCGCTTCTCATCCCCTCTCGGGTGAGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGTCGGGCAAGAGAGCCTCCGCCCACGTCCTGACGTCCCTCGTCCAGCGGTGGCTCAAGGAACAGCGGCTTCAATGGGGCCGCCACCTTTCAGCGGCGGAGAGGTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTCGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGTGTTGGTGAACACAACCTTAGCCAACTCGCTCATGTTGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGATCGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCGGCTTCAATGGGGCCGCCACCTTTCAGCGGCGGAGAGGTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTCGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGATTCAAACACACCTCTCCGACCGTGCTGTTCGCAGAGCGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGATCGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGTTGGCGCGGACCGTTGCGGCGCGCGCCGGACCCCCTGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCGAGGCAGAGGAGCGGATGTTTAACACCGGAGACTTGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGAGAGCGCCGAGGCGCGCGGGAGGATGGAGATGAGCATGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCTCCGAGGCAACCAGCGCATCGGCCGCGCACGTGAGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCGCGGCGCAGACGGCGCCGGAGCAGACGATCGCGGAGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGAAGATCGTCGAGGCCACTGGCAACGTTCGCCAGGTCTAGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGTAGAAGGCGGGCCGGAACCCTCGCACGTGGTCGGCGTAGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCACGTTCCTGATCACGACGACGAAGATGCTCATCAGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGGCCCTGCTACAACGTAGAGCTTGAAGACCCGGACCGTATGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGGTCTCCCCGACGACCCTCACGCCGGGCGTCTACCTGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGACCGCGTCGTCGTACACGCTCTCCGGCAGATCGAAGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCGTGCGTGCCGTTCGCACGGACGCGCCGGATTTTGTCCGGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCTCGATGGCGCGCCCCGAGGCGTCGCAGCCCTCCTGGCCGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGGCGGGAGTTCGACCGGCTCCGCGGCGACGCGAAGGCGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCCGCCGGTCGTCGTGGTCGGCGGCGCGCGCGTGCCAGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGGGCCCAGTGGATGGATAATAGCGGCATGTTCCGCAAGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCGCATAGGCACTGCTGCGACGTCAGGAACGTGCACCTGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGGATGCAGGGATTTTTCGTCCCTCCTACGCATGCCATCGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCCAGCAAGGCTCCGGCATCGAACACGACCTTAGAGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCGCGTTCGGACGCGATGCCTCGATGTCGCGGCTGTTGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCCACCTCGCAGACACGTGGGAGGTCATCTGCAAGACGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGTCGTGCAGGTCGACTTGACGGTGCGCCCGACGGAGCGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCTGCGCAGCGAGTCCGCGCGCGACGCGTTCGTCGAGGTGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGATGGAAGCGAGATGAGCTGTGGTTCACATTTGCGGAGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCTCAAGGAAACAGGGCGCACGGGGAGCTCCCCGAACTTGCAGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCGCGCGGCAGGGCCATTACGCAGCGCTCCCCTCTCCGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGGTGCTCTCAGCCCAGTCGCGCACGCTCTCCGCGGTGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGTCAGCGTCGACGGGACGTCGCCGAGCAGGGCGAGCGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGCACACGCGCTGTGCGAACCGGTCGATCGCGTACCTCGTGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGTGGGTGAGCCAGTCAGCGAAGAGTATACGTGCACTTGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAGGCGGTTTTCGCTGTGCCGGAACCGGAGCCACTCTGGATGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG

>NC_021658|37|3|9167757-9168255|PILER-CR
GCTTCCATGGGGCCGCCGCCTTTCAGCGGCGGAGA	GCCGGCCTCGTCGCTTCTCATCCCCTCTCGGGTGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGA	GTCGGGCAAGAGAGCCTCCGCCCACGTCCTGACGTCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
GCTTCAATGGGGCCGCCACCTTTCAGCGGCGGAGA	GGTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGA	GTGTTGGTGAACACAACCTTAGCCAACTCGCTCATGTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGA	TCGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
GCTTCAATGGGGCCGCCACCTTTCAGCGGCGGAGA	GGTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGATTCAAACACACCTCTCCGACCGTGCTGTTCGCAGAGCGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGATCGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TTGGCGCGGACCGTTGCGGCGCGCGCCGGACCCCCTG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGAGGCAGAGGAGCGGATGTTTAACACCGGAGACTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	AGAGCGCCGAGGCGCGCGGGAGGATGGAGATGAGCAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCCGAGGCAACCAGCGCATCGGCCGCGCACGTGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGGCGCAGACGGCGCCGGAGCAGACGATCGCGGA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	AAGATCGTCGAGGCCACTGGCAACGTTCGCCAGGTCTA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TAGAAGGCGGGCCGGAACCCTCGCACGTGGTCGGCGTA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CACGTTCCTGATCACGACGACGAAGATGCTCATCAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCCCTGCTACAACGTAGAGCTTGAAGACCCGGACCGTAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GTCTCCCCGACGACCCTCACGCCGGGCGTCTACCT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	ACCGCGTCGTCGTACACGCTCTCCGGCAGATCGAA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGTGCGTGCCGTTCGCACGGACGCGCCGGATTTTGTCCGG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCGATGGCGCGCCCCGAGGCGTCGCAGCCCTCCTGGCC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCGGGAGTTCGACCGGCTCCGCGGCGACGCGAAGGC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCGCCGGTCGTCGTGGTCGGCGGCGCGCGCGTGCCA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GGCCCAGTGGATGGATAATAGCGGCATGTTCCGCAA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCATAGGCACTGCTGCGACGTCAGGAACGTGCACCT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GATGCAGGGATTTTTCGTCCCTCCTACGCATGCCATC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCAGCAAGGCTCCGGCATCGAACACGACCTTAGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGTTCGGACGCGATGCCTCGATGTCGCGGCTGTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCACCTCGCAGACACGTGGGAGGTCATCTGCAAGAC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TCGTGCAGGTCGACTTGACGGTGCGCCCGACGGAGCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTGCGCAGCGAGTCCGCGCGCGACGCGTTCGTCGAGGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	ATGGAAGCGAGATGAGCTGTGGTTCACATTTGCGGA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCAAGGAAACAGGGCGCACGGGGAGCTCCCCGAACTTGCA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGCGGCAGGGCCATTACGCAGCGCTCCCCTCTCCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GTGCTCTCAGCCCAGTCGCGCACGCTCTCCGCGGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TCAGCGTCGACGGGACGTCGCCGAGCAGGGCGAGC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CACACGCGCTGTGCGAACCGGTCGATCGCGTACCTCGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TGGGTGAGCCAGTCAGCGAAGAGTATACGTGCACTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCGGTTTTCGCTGTGCCGGAACCGGAGCCACTCTGGAT


>NC_021658|37|33|9167757-9170662|CRISPRCasFinder
GCTTCCATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCGGCCTCGTCGCTTCTCATCCCCTCTCGGGTGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TCGGGCAAGAGAGCCTCCGCCCACGTCCTGACGTCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
GCTTCAATGGGGCCGCCACCTTTCAGCGGCGGAGAG	GTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TGTTGGTGAACACAACCTTAGCCAACTCGCTCATGTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAT	CGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
GCTTCAATGGGGCCGCCACCTTTCAGCGGCGGAGAG	GTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAT	TCAAACACACCTCTCCGACCGTGCTGTTCGCAGAGCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAT	CGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TTGGCGCGGACCGTTGCGGCGCGCGCCGGACCCCCTG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGAGGCAGAGGAGCGGATGTTTAACACCGGAGACTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	AGAGCGCCGAGGCGCGCGGGAGGATGGAGATGAGCAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCCGAGGCAACCAGCGCATCGGCCGCGCACGTGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGGCGCAGACGGCGCCGGAGCAGACGATCGCGGA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	AAGATCGTCGAGGCCACTGGCAACGTTCGCCAGGTCTA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TAGAAGGCGGGCCGGAACCCTCGCACGTGGTCGGCGTA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CACGTTCCTGATCACGACGACGAAGATGCTCATCAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCCCTGCTACAACGTAGAGCTTGAAGACCCGGACCGTAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GTCTCCCCGACGACCCTCACGCCGGGCGTCTACCT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	ACCGCGTCGTCGTACACGCTCTCCGGCAGATCGAA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGTGCGTGCCGTTCGCACGGACGCGCCGGATTTTGTCCGG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCGATGGCGCGCCCCGAGGCGTCGCAGCCCTCCTGGCC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCGGGAGTTCGACCGGCTCCGCGGCGACGCGAAGGC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCGCCGGTCGTCGTGGTCGGCGGCGCGCGCGTGCCA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GGCCCAGTGGATGGATAATAGCGGCATGTTCCGCAA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCATAGGCACTGCTGCGACGTCAGGAACGTGCACCT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GATGCAGGGATTTTTCGTCCCTCCTACGCATGCCATC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCAGCAAGGCTCCGGCATCGAACACGACCTTAGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGTTCGGACGCGATGCCTCGATGTCGCGGCTGTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCACCTCGCAGACACGTGGGAGGTCATCTGCAAGAC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TCGTGCAGGTCGACTTGACGGTGCGCCCGACGGAGCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTGCGCAGCGAGTCCGCGCGCGACGCGTTCGTCGAGGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	ATGGAAGCGAGATGAGCTGTGGTTCACATTTGCGGA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCAAGGAAACAGGGCGCACGGGGAGCTCCCCGAACTTGCA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGCGGCAGGGCCATTACGCAGCGCTCCCCTCTCCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GTGCTCTCAGCCCAGTCGCGCACGCTCTCCGCGGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TCAGCGTCGACGGGACGTCGCCGAGCAGGGCGAGC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CACACGCGCTGTGCGAACCGGTCGATCGCGTACCTCGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TGGGTGAGCCAGTCAGCGAAGAGTATACGTGCACTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCGGTTTTCGCTGTGCCGGAACCGGAGCCACTCTGGAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG

>NC_021658|37|7|9167757-9170662|CRT
GCTTCCATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCGGCCTCGTCGCTTCTCATCCCCTCTCGGGTGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TCGGGCAAGAGAGCCTCCGCCCACGTCCTGACGTCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
GCTTCAATGGGGCCGCCACCTTTCAGCGGCGGAGAG	GTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TGTTGGTGAACACAACCTTAGCCAACTCGCTCATGTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAT	CGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
GCTTCAATGGGGCCGCCACCTTTCAGCGGCGGAGAG	GTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAT	TCAAACACACCTCTCCGACCGTGCTGTTCGCAGAGCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAT	CGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TTGGCGCGGACCGTTGCGGCGCGCGCCGGACCCCCTG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGAGGCAGAGGAGCGGATGTTTAACACCGGAGACTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	AGAGCGCCGAGGCGCGCGGGAGGATGGAGATGAGCAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCCGAGGCAACCAGCGCATCGGCCGCGCACGTGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGGCGCAGACGGCGCCGGAGCAGACGATCGCGGA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	AAGATCGTCGAGGCCACTGGCAACGTTCGCCAGGTCTA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TAGAAGGCGGGCCGGAACCCTCGCACGTGGTCGGCGTA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CACGTTCCTGATCACGACGACGAAGATGCTCATCAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCCCTGCTACAACGTAGAGCTTGAAGACCCGGACCGTAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GTCTCCCCGACGACCCTCACGCCGGGCGTCTACCT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	ACCGCGTCGTCGTACACGCTCTCCGGCAGATCGAA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGTGCGTGCCGTTCGCACGGACGCGCCGGATTTTGTCCGG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCGATGGCGCGCCCCGAGGCGTCGCAGCCCTCCTGGCC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCGGGAGTTCGACCGGCTCCGCGGCGACGCGAAGGC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCGCCGGTCGTCGTGGTCGGCGGCGCGCGCGTGCCA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GGCCCAGTGGATGGATAATAGCGGCATGTTCCGCAA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCATAGGCACTGCTGCGACGTCAGGAACGTGCACCT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GATGCAGGGATTTTTCGTCCCTCCTACGCATGCCATC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCAGCAAGGCTCCGGCATCGAACACGACCTTAGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGTTCGGACGCGATGCCTCGATGTCGCGGCTGTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCACCTCGCAGACACGTGGGAGGTCATCTGCAAGAC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TCGTGCAGGTCGACTTGACGGTGCGCCCGACGGAGCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTGCGCAGCGAGTCCGCGCGCGACGCGTTCGTCGAGGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	ATGGAAGCGAGATGAGCTGTGGTTCACATTTGCGGA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCAAGGAAACAGGGCGCACGGGGAGCTCCCCGAACTTGCA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGCGGCAGGGCCATTACGCAGCGCTCCCCTCTCCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GTGCTCTCAGCCCAGTCGCGCACGCTCTCCGCGGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TCAGCGTCGACGGGACGTCGCCGAGCAGGGCGAGC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CACACGCGCTGTGCGAACCGGTCGATCGCGTACCTCGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TGGGTGAGCCAGTCAGCGAAGAGTATACGTGCACTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCGGTTTTCGCTGTGCCGGAACCGGAGCCACTCTGGAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG

>NC_021658|37|4|9168369-9170662|PILER-CR
	GCCGGCCTCGTCGCTTCTCATCCCCTCTCGGGTGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGA	GTCGGGCAAGAGAGCCTCCGCCCACGTCCTGACGTCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
GCTTCAATGGGGCCGCCACCTTTCAGCGGCGGAGA	GGTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGA	GTGTTGGTGAACACAACCTTAGCCAACTCGCTCATGTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGA	TCGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCG
GCTTCAATGGGGCCGCCACCTTTCAGCGGCGGAGA	GGTGATTCCGGGCGGCGGAAGCGTGCTCGCGGTGGTC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGATTCAAACACACCTCTCCGACCGTGCTGTTCGCAGAGCGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGATCGGGATCGCCCTCGTCCAGCGGTGGCTCAAGGAACAGCGGCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TTGGCGCGGACCGTTGCGGCGCGCGCCGGACCCCCTG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGAGGCAGAGGAGCGGATGTTTAACACCGGAGACTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	AGAGCGCCGAGGCGCGCGGGAGGATGGAGATGAGCAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCCGAGGCAACCAGCGCATCGGCCGCGCACGTGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGGCGCAGACGGCGCCGGAGCAGACGATCGCGGA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	AAGATCGTCGAGGCCACTGGCAACGTTCGCCAGGTCTA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TAGAAGGCGGGCCGGAACCCTCGCACGTGGTCGGCGTA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CACGTTCCTGATCACGACGACGAAGATGCTCATCAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCCCTGCTACAACGTAGAGCTTGAAGACCCGGACCGTAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GTCTCCCCGACGACCCTCACGCCGGGCGTCTACCT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	ACCGCGTCGTCGTACACGCTCTCCGGCAGATCGAA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGTGCGTGCCGTTCGCACGGACGCGCCGGATTTTGTCCGG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCGATGGCGCGCCCCGAGGCGTCGCAGCCCTCCTGGCC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCGGGAGTTCGACCGGCTCCGCGGCGACGCGAAGGC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCGCCGGTCGTCGTGGTCGGCGGCGCGCGCGTGCCA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GGCCCAGTGGATGGATAATAGCGGCATGTTCCGCAA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCATAGGCACTGCTGCGACGTCAGGAACGTGCACCT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GATGCAGGGATTTTTCGTCCCTCCTACGCATGCCATC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCAGCAAGGCTCCGGCATCGAACACGACCTTAGAG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGTTCGGACGCGATGCCTCGATGTCGCGGCTGTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CCACCTCGCAGACACGTGGGAGGTCATCTGCAAGAC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TCGTGCAGGTCGACTTGACGGTGCGCCCGACGGAGCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTGCGCAGCGAGTCCGCGCGCGACGCGTTCGTCGAGGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	ATGGAAGCGAGATGAGCTGTGGTTCACATTTGCGGA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CTCAAGGAAACAGGGCGCACGGGGAGCTCCCCGAACTTGCA
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CGCGCGGCAGGGCCATTACGCAGCGCTCCCCTCTCCG
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GTGCTCTCAGCCCAGTCGCGCACGCTCTCCGCGGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TCAGCGTCGACGGGACGTCGCCGAGCAGGGCGAGC
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	CACACGCGCTGTGCGAACCGGTCGATCGCGTACCTCGT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	TGGGTGAGCCAGTCAGCGAAGAGTATACGTGCACTT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG	GCGGTTTTCGCTGTGCCGGAACCGGAGCCACTCTGGAT
GCTTCAATGGGGCCGCCGCCTTTCAGCGGCGGAGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020738350.1|9174586_9175615_+|PA0069-family-radical-SAM-protein	unknown	unknown	gnl|CDD|275263
NC_021658.1|WP_044989004.1|9177142_9178585_-|DUF814-domain-containing-protein	unknown	unknown	gnl|CDD|224212
NC_021658.1|WP_020738337.1|9156664_9158833_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173810
NC_021658.1|WP_020738352.1|9176559_9177018_+|TerB-family-tellurite-resistance-protein	unknown	unknown	gnl|CDD|143580
NC_021658.1|WP_148314063.1|9156435_9156651_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314064.1|9166110_9167154_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738346.1|9171278_9172070_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738338.1|9159093_9159417_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738344.1|9165340_9166018_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738348.1|9172672_9173836_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226984
NC_021658.1|WP_044989003.1|9173920_9174343_-|hypothetical-protein	unknown	unknown	gnl|CDD|275159
NC_021658.1|WP_020738342.1|9162970_9163933_-|L-lactate-dehydrogenase	unknown	unknown	gnl|CDD|133428
NC_021658.1|WP_020738343.1|9164083_9165292_-|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370
NC_021658.1|WP_020738351.1|9175754_9176534_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|227333
NC_021658.1|WP_020738355.1|9179539_9180283_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|335469
NC_021658.1|WP_020738340.1|9160367_9161969_-|PAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NC_021658.1|WP_063752050.1|9159707_9160274_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738347.1|9172173_9172620_+|CoA-binding-protein	unknown	unknown	gnl|CDD|224745
NC_021658.1|WP_020738341.1|9162297_9162720_-|DUF1810-domain-containing-protein	unknown	unknown	gnl|CDD|378062
NC_021658.1|WP_148314065.1|9178750_9179422_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020738337.1|9156664_9158833_+|S8-family-serine-peptidase	gnl|CDD|173810	cd07484, Peptidases_S8_Thermitase_like, Peptidase S8 family domain in Thermitase-like proteins. Thermitase is a non-specific, trypsin-related serine protease with a very high specific activity. It contains a subtilisin like domain. The tertiary structure of thermitase is similar to that of subtilisin BPN'. It contains a Asp/His/Ser catalytic triad. Members of the peptidases S8 (subtilisin and kexin) and S53 (sedolisin) clan include endopeptidases and exopeptidases. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. Serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of subtilisin. The serine residue here is the nucleophilic equivalent of the serine residue in the S8 family, while glutamic acid has the same role here as the histidine base. However, the aspartic acid residue that acts as an electrophile is quite different. In S53 the it follows glutamic acid, while in S8 it precedes histidine. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. There is a great diversity in the characteristics of their members: some contain disulfide bonds, some are intracellular while others are extracellular, some function at extreme temperatures, and others at high or low pH values.	3.45268e-67
NC_021658.1|WP_044989004.1|9177142_9178585_-|DUF814-domain-containing-protein	gnl|CDD|224212	COG1293, COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription].	3.13823e-29
NC_021658.1|WP_020738350.1|9174586_9175615_+|PA0069-family-radical-SAM-protein	gnl|CDD|275263	TIGR04470, hypothetical_protein_ALIPUT_00462, radical SAM mobile pair protein B. Members of this family are the downstream member (B) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.	1.65947e-20
NC_021658.1|WP_020738348.1|9172672_9173836_+|AAA-family-ATPase	gnl|CDD|226984	COG4637, COG4637, Predicted ATPase [General function prediction only].	6.24397e-45
NC_021658.1|WP_044989003.1|9173920_9174343_-|hypothetical-protein	gnl|CDD|275159	TIGR04366, hypothetical_protein, cupin fold metalloprotein, WbuC family. Members of this family show sequence similarity to cupin fold proteins (see pfam07883), including conserved His residues likely to serve as metal-binding ligands. Many members occur in bacterial O-antigen biosynthesis regions. Some members have acquired the gene symbol wbuC (e.g. Jarvis, et al, 2011), but publications using this term do not ascribe a function.	0.000613017
NC_021658.1|WP_020738342.1|9162970_9163933_-|L-lactate-dehydrogenase	gnl|CDD|133428	cd05292, LDH_2, A subgroup of L-lactate dehydrogenases. L-lactate dehydrogenases (LDH) are tetrameric enzymes catalyzing the last step of glycolysis in which pyruvate is converted to L-lactate. This subgroup is composed predominantly of bacterial LDHs and a few fungal LDHs. Bacterial LDHs may be non-allosteric or may be activated by an allosteric effector such as fructose-1,6-bisphosphate. LDHs are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	2.26734e-176
NC_021658.1|WP_020738343.1|9164083_9165292_-|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	2.19057e-32
NC_021658.1|WP_020738355.1|9179539_9180283_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	1.4919e-12
NC_021658.1|WP_020738340.1|9160367_9161969_-|PAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	1.52906e-41
NC_021658.1|WP_020738352.1|9176559_9177018_+|TerB-family-tellurite-resistance-protein	gnl|CDD|143580	cd07176, terB, tellurite resistance protein terB. This family contains uncharacterized bacterial proteins involved in tellurium resistance. The prototype of this CD is the Kp-terB protein from Klebsiella pneumoniae, whose 3D structure was recently determined. The biological function of terB and the mechanism responsible for tellurium resistance are unknown.	2.57814e-07
NC_021658.1|WP_020738341.1|9162297_9162720_-|DUF1810-domain-containing-protein	gnl|CDD|378062	pfam08837, DUF1810, Protein of unknown function (DUF1810). This is a family of uncharacterized proteins. The structure of one of the members in this family has been solved and it adopts a mainly alpha helical structure.	9.97635e-90
NC_021658.1|WP_020738347.1|9172173_9172620_+|CoA-binding-protein	gnl|CDD|224745	COG1832, COG1832, Predicted CoA-binding protein [General function prediction only].	4.85337e-40
NC_021658.1|WP_020738351.1|9175754_9176534_+|HAMP-domain-containing-protein	gnl|CDD|227333	COG5000, NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms].	0.000607807

Protein sequences

>NC_021658.1|WP_148314064.1|9166110_9167154_-|hypothetical-protein
MARRSSGVIVVAACAAALWQGCGSPYSYDCRETRSCPCECTSVPPLGFTDPVLLYIGSELSAPECPPLSAPAKVYEGHADLDVPYECPACRCSEPTCGLPSVLRASDAPLCQGPTFTAFGAPTGWDGSCVAATAVPDERLASLVIAPVTATACEPIEPEPVPRRSARDGFISPWKTLARACKGDPIAVDDEDVFGDTDEPVCPAGEKCWPAPEPPPPGFRQCIMYLGGGEPVCPDDYPLMHVFYRDFEDTRECTPCACTPTGESSCSASVSAYADDACTDAFASHAVGTEAGLCVDVMEGVALKSMSATWTTHRPGTCETSGGELLGEATPTHPSTFCCQPLPAPPR
>NC_021658.1|WP_020738344.1|9165340_9166018_-|hypothetical-protein
MNLDQLQAPRADIAHGVSFAALRPQDACRRLAVAIGISAGAAILLWPKAALANIGIPMLIFAWPASWIAFVPVVLVEAAVARRVLRLPTREAIKLSLAANAWSTLAGIPITWALLTVLEMTVAPTLSRARGDLGTAATLLMVPISAPWLGPVKESWRVLAAGAFLCVPFFFASVWIEARSAGRRVPAADALRWAKRANSATYGFFLVALALAALISWTSRAGSAG
>NC_021658.1|WP_020738343.1|9164083_9165292_-|mechanosensitive-ion-channel
MNLDRLPALWADLLRHPTSLPVALGAAIAVLALGFFAYRLLFALLSRAARATQTSLDDLLLRRMRLPARLLVALLALHTFIALRGGELPTLHKGVLLLELALASYLAIEMAETMVIDYWLAERRKVQLPALVRHLLLAILYLVAGLSIVGAVTGVDLVPLLATSTVITVVLGLALQDTLGNLFAGLALHSERSFGVGDWILVDGIEGQVVYVGWRSTRLRTFSGDIVILPNSIIAKARVQNFCAPDRTCARNIEMLVALGAAPEAVERAAQRAYAQVPDILREPPPRLWLAAVTPLFQRYVIKFWIADFERHDLLESELMRAFFRACRDEGVALSPAAAQPGLAVDPRILDPRAPVDPTAAPVVLPAIVAVPAAPAPTVASGKPDAGSPRQQGRSAEPLPER
>NC_021658.1|WP_020738342.1|9162970_9163933_-|L-lactate-dehydrogenase
MPDNQPVSPNKVAVVGAGSVGATIAYACLLRGVAKEVALFDVNRAKVDAEVLDLNHGLQFVPPATLEGSDDVEVCRGAHVVVITAGAKQKPGQSRMDLATANVAICRELLPRLQAVAPDALYLLVTNPVDVITYVTLKLTGLPPARVLGSGTVLDSSRFRFLIARRLNVAVQNVHAYIAGEHGDSEVPLWSSASVANIPLDAWSVPGHGKLAAGDRAEIFSNVKNAAAQVISGKGATNYAIGLATAKILEALLRDENRVLPVSSLLSGYRGIDDVCLSVPCVVNRSGVESQLPIPMSPEEEAGVRASADTIRKAIRSLGF
>NC_021658.1|WP_020738341.1|9162297_9162720_-|DUF1810-domain-containing-protein
MPDPYDLQRFVDAQAPVYDRVVAELRRGQKTGHWMWFIFPQLRGLGHSAMAHRYGIASKAEAEAYLQHPTLGPRLIECARLVNQIEGCSLYDIFDSPDDMKFCSSMTLFARAAPDNETFLAALEKYCGGELDPRTLALLE
>NC_021658.1|WP_020738340.1|9160367_9161969_-|PAS-domain-containing-protein
MPSDAPVDLCSLAFTCSVDPLLLLDETGRILALNPAAERLLSTPGATARGGPVDEALRPQPPLGALLDEVIRDRAPRALPPDFTLHLASERAVLAEGSLSPLVDPAGACAGVLLALRDVTERRRAEQAARDRAARLHAAVEALDVGLVIYDAEERLCFFNTAYKSHYPECAAAIQVGNTFEDVVREGCRNGIHLHSGLSEEEWVAGRLADHRRSGDVYMRRFGERWLTLKSTRLADGSTVGLRIDTTEIKQAELALERERQFIRLVLDTIPIVVTVKDRDGKMKLVSKSYAALYDTTPEAAVGKTVGDLPSSHAELSTIGEMDREVLARMQPVSRVQPVARPNGNVRWMSIVKVPLIEQDGTTHILAIGMDITAQREHEEHMAATIAELERQRQAFADQLAVIQRQQALIRALSTPILQVAEGVVAVPLIGALDDARAADVTSKLLDEVVRTGARFAIIDVTGIESVDAATADHLVRIVRAIRLLGASGVLTGIGPAVAQSMCGLEVDLSGVTTHGNLRAGIEVCLRALPRRR
>NC_021658.1|WP_063752050.1|9159707_9160274_+|hypothetical-protein
MTDEPKVKGVAFRSVYVSLGKLRGEPLQKLSLDEMCEPLRAAMRYGSIVSTGWYPIGWYKDLFQAIRRASGEGKDLVHQIGRQCTRDDMSGIYKVIAALISPSTLFSLGQRVFANYYSVGRVQVLESRRGFTHARWSGCYGFDENMWTEVIGSCEQLLEIGGASHVRQRIIAGGGDADDHLELTAHWS
>NC_021658.1|WP_020738338.1|9159093_9159417_+|hypothetical-protein
MLLDPPATLGRHTVTLYLGPAEDQGPEANESLGEAISFDRRDPRSIRRAQEIIQDRLRLSVAPTLCDEPSPGLGAALGRLLAALVNVLERWHWRVRHRKFVARAPAP
>NC_021658.1|WP_020738337.1|9156664_9158833_+|S8-family-serine-peptidase
MERVLARARRSARRAGAGLLIALSSLPLAAGCSADEGELELDAGASARALQVPSDPLFSLQWHYPAIRLPEAWELTTGTPNVRIAILDTGRGVHPDLNGKWVPGLEYDAVAQDANASNTGWAHANHVAGIAGGSTNNAEGGAGVCWGCQLLNVDVANGDFPDLLNMPRAVRWAVDNGAQVINLSLGENLNVPCSDPRYSALRDALAFAASRNVTVVAAAGNLSRDFATTVPAACPGVISVAAADHNNQLASYSNHGAVTLAAPGGGGVFTTPNGFGAPIGCPEDYLSRFTSDTVGVVSAWTTSNGTPCYRYLSGTSMAAPHVAGVVGLMLSRNPNLTPAQIRQILQSTAQPMPSCGGNCGAGLLDAAAAVAQAAALPVDDAAPVARFTAQCAGLDCWFDGSGSTDDRGIVAYQWMLPGPVVGPSMTPVSHPGQHLRTGAAASFLLPGYGSHLVRLRVTDAAGQSHELTQTVTPQQAPLDPRPGSYINTQRAGNTLDLHQTANGDWVLGWFTFDTSGEPVWYNSAVGPVINSRFQQPLMRYTWANNVATETQVGTIALDFSTSQAVWVSWVLHGVAGGERYQYLRGGDGRSGLWYAPSQPGWGFSVQESFWYFHATVTFYLPDGEPRWMSGWNWAGSNVSLALEYLRGPGLCPSCGGKDATVVHQDWSHPERPSSMNLQISDGASTAGWGSTDISRFIASPTTNWVVPVWTRSPLPIGLLTRP
>NC_021658.1|WP_148314063.1|9156435_9156651_+|hypothetical-protein
MQQNERDDPAIAPIHPALAGPQRWPGRPPLSLTLDRGTGQESPGSAPGLIHHLSSSLATVLGQEVQGNAAV
>NC_021658.1|WP_020738346.1|9171278_9172070_+|hypothetical-protein
MARLTLRQKAERVLKLLLALRTNEIAAALVAHGFTDADLAEGWRLLQGLTRPRLDIDVGTSAPEPDLVAALDGWQKRWFPIAAATLKRRHPEVHAWMFRNLGQTEGAAVVVSVGTFVERWDQLARRKDKGGPERDGREARKLLARRGITREIVDEARELLARAEKVEPAADRSPADPDHDGEQAEADLWAWYLEWSAVVRSAVQDRKLLRELGYRRPSGRPSGGTTPIAQPPRGSIQRRADQSDSPPRPRPTRARASAGRRPR
>NC_021658.1|WP_020738347.1|9172173_9172620_+|CoA-binding-protein
MNDIRDISDDDARVAELVRGARRVAVLGIKTEAQADQPAFYVPSYLHSAGVEVIPVPVYYPDVKTILGQQVYRRVADVPGPIDIVDVFRRGQDVAAHLDDLLAARPRAVWLQSGIRNDQVAERLVEAGILVVQDRCLMVDHRRFAGRG
>NC_021658.1|WP_020738348.1|9172672_9173836_+|AAA-family-ATPase
MLLKSLRLDRFLSFGPGSDPIELSKLNVLIGPNGSGKSNFIEAIGFLRAAPTDLLAPVRQGGGVSAWIWRGEPGAKAEVEAVLAYRPESSWNLRHRVSFTELGARLEIVDERIEDEEPPAEPTGQHVYFGYEHGRPMLNVRNGKRELRREDIDPQQSILSQRKDPDHYPELSFVGDHYSKIRLHRDWGLGRASSPRYPQPSDLPTDHLREDAQNLGLILNRFRRDIPTKRVLIDALQQVFDGAVDFSVQIEGGTVQIFLEEERWTLPATRLSDGTIRWLALLAILLDPAPPPLVCIEEPELGLHPDLMPTLARLLLGASERTQVIVTTHSDVLVDALSDAPETVLVCERHEGRTTLRRLTRDALSTWLEAYTLGELWRKGELGGTRW
>NC_021658.1|WP_044989003.1|9173920_9174343_-|hypothetical-protein
MANPTQPGFDLRSTYLHLADGGDALPIEVRPTFWQELMSGDSEAADIRRITDEGGWLVIRYPLTEDTPQWEMHPAGDEILVLLSGASDVVLEEQGGERVVALLAGAACKVPQGAWHRILVREPGDLLSITYGKGTQHRPL
>NC_021658.1|WP_020738350.1|9174586_9175615_+|PA0069-family-radical-SAM-protein
MPRPVNNPPNPWSSTQVEYLEEAPPATLQVFEEQARSIITANDSPDLPFQYSVNPYRGCIHACAYCYARPSHQYLGWGAGTDFDRKIVVKANAPELLEKELNKPGWQGDTIVFSGNVDCYQPLEASYELTRRCLEICLAFRNPVGLITKGALVRRDAALLGELARRARARVHLSIPFADDAVARKMEPYASRSSLRFEAMRALSDAGVPTGISLSPLIPGLNDSDVPELLERARDAGAQSAFMMPLRLPREVLPVFDERLEEAFPDRAGKVRRGIQEMRGGKMNEAAFGARFQGAGARWAAIQRLFEVHCQRLGLNAAREREAADERSTFRRPSRQGTLFDL
>NC_021658.1|WP_020738351.1|9175754_9176534_+|HAMP-domain-containing-protein
MTSPAQDRATARPAPRRKLLLNPRFQLKYTGLLVSVVLAVMVVLGLVIWQTASVANEQAQYAASQAELALKEAANSAKILRMSTAALGGDGAELGTTLDEELEKTNREYERNLAEVGRRRSEVEALRQRLLNILVGGGVFLLVVLGVLGIFITQRIVGPVHQMKRLCRQVGTTRLTIGEGLRKGDELGDLFDTFVQMTYSLKALQTGRLATLDAAIERAEAEKASAEVLAGLRALRAQLCLGLSESEAVRRRAPKGGES
>NC_021658.1|WP_020738352.1|9176559_9177018_+|TerB-family-tellurite-resistance-protein
MKPPALVHQAAGLLRARFDLNEYNPTPIVDLGALVANADGNVDAEEIDALRQLIEPMLGAELNAELVRYLIEASLKVIAAAGVEPRVRLLAEILMDCDAVEEGVIVALAVAHASEGISDAERAVIASLARAADLPARRLDQLNEQVRAAFTA
>NC_021658.1|WP_044989004.1|9177142_9178585_-|DUF814-domain-containing-protein
MLGAGIGPRVAGVGVLPRLPRLRAGASHPLLSAMRAHLVGRRVLAIEVRGDGVVVVAGDALLAEGDREGESASGAGSSPPAPGLSRGSPAPGLPAPGLGPAAPAPGLSPAPAAAARLELAPGRRGEVRLLDGAGNLILRWPPQGSAPPAETAYPEDPLAAGAALVEASDDAAAGQEKAALARAVKARRAALERRAEAVRGDLGRLGSVARLQKTGQLLLAQGARVPRGAAKALLDDWETGGKLEVALDPARPAKAQAEAFFAKARRYQRGEAVMRARLAETERALEAIAALEADVAAAEARPEALEPLAQRARSLGVARADIAGAGAALAGEPGAAGGARGPRAGRTAPRRPFHAYRSASGAAILVGRGAEDNDALTTKHARPHDLWLHAKGVAGSHVVVPLPKGASCPAEVLVDAATLAAHFSDARGEAVCEVSYVPRRYVRKPRGAAPGAVVFDREKVIAVRIEGARLSRLLATKEEG
>NC_021658.1|WP_148314065.1|9178750_9179422_-|hypothetical-protein
MGMTLLRMRFAALAVLALGSACGGNVVVDGMPGEGSGGAGATSSSASGTSNVGVTSTGGGGGDARSKCLEYCEMFLPTCGAAPGSCGDVCDQQLSTAPACNDRLAPFFDCAIEAFNCDVIPSRCQPLLDEYDACAFGAGSGSGSGAGADCGGLECFGGGDRVCSCKGSCSSVDFAVECRPTMGGADLSCSCFVDGSEVASCGDIGPACDLARLCCEPIFELFR
>NC_021658.1|WP_020738355.1|9179539_9180283_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MLLDLLLAPLLAQADALPRPGAPASCPPDMVLVEGTHRENVQRICTSYRGGHCFSFFPGLFAAEPRFTPVRTCMDRHEWPNRAGALPVVMLRFVEAERECAAAGKRLCTEFEWELACEGPSALPFPYGYAQDPAACNVSKPYRGISERRLASDDPAVRAAETQRLWQGEPSGSYPACVSPYGVVDLVGNVEEWVSTSRPEWPHRSSLKGGYWSKPWAGCRGTNDSHGPMFRFYEIGFRCCKDPGAGT

Crispr_ID: NC_021658_38

• CRISPR_ID: NC_021658_38
• CRISPR_location: 9285648-9285732
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_38

Consensus_repeat	Method
GCTGACGTGGTTCAGAGATTAGGGGGGAGG	CRISPRCasFinder

spacers of NC_021658_38

>38.1|9285678|25|NC_021658|CRISPRCasFinder
CCCGCCTCCTGTGCGGGAGGGCTCG

CRISPR arrays and Neighbor proteins around NC_021658_38

CRISPR arrays

The CRISPR arrays of NC_021658_38

>merge|NC_021658|38|9285648-9285732|CRISPRCasFinder
GCTGACGTGGTTCAGAGATTAGGGGGGAGGCCCGCCTCCTGTGCGGGAGGGCTCGGCTGACGTGGTTCAGAGATTAGGGGGGAGG

>NC_021658|38|34|9285648-9285732|CRISPRCasFinder
GCTGACGTGGTTCAGAGATTAGGGGGGAGG	CCCGCCTCCTGTGCGGGAGGGCTCG
GCTGACGTGGTTCAGAGATTAGGGGGGAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020738423.1|9271530_9271935_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738426.1|9274781_9275603_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738438.1|9299768_9300299_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_148314925.1|9302901_9307416_+|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl|CDD|259906
NC_021658.1|WP_020738431.1|9283991_9285530_+|cysteine--tRNA-ligase	unknown	unknown	gnl|CDD|234705
NC_021658.1|WP_187346056.1|9271873_9272812_-|hypothetical-protein	unknown	unknown	gnl|CDD|197338
NC_021658.1|WP_020738439.1|9301167_9301953_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|100107
NC_021658.1|WP_044989023.1|9282770_9283550_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|227135
NC_021658.1|WP_187345681.1|9297586_9299125_-|PilT/PilU-family-type-4a-pilus-ATPase	unknown	unknown	gnl|CDD|225364
NC_021658.1|WP_020738425.1|9273267_9274410_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226984
NC_021658.1|WP_020738434.1|9289122_9289938_-|arylamine-N-acetyltransferase	unknown	unknown	gnl|CDD|366312
NC_021658.1|WP_020738444.1|9312265_9314092_+|hypothetical-protein	unknown	unknown	gnl|CDD|274824
NC_021658.1|WP_148314924.1|9277095_9280974_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020738429.1|9281152_9282718_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020738440.1|9301999_9302233_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738435.1|9290370_9296325_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_021658.1|WP_148314078.1|9268510_9269158_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044986356.1|9276004_9276922_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738432.1|9286248_9288747_+|LamG-domain-containing-protein	unknown	unknown	gnl|CDD|379155
NC_021658.1|WP_020738436.1|9296514_9297585_-|PilT/PilU-family-type-4a-pilus-ATPase	unknown	unknown	gnl|CDD|225364

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020738438.1|9299768_9300299_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.0022026
NC_021658.1|WP_148314925.1|9302901_9307416_+|multicopper-oxidase-domain-containing-protein	gnl|CDD|259906	cd11020, CuRO_1_CuNIR, Cupredoxin domain 1 of Copper-containing nitrite reductase. Copper-containing nitrite reductase (CuNIR), which catalyzes the reduction of NO2- to NO, is the key enzyme in the denitrification process in denitrifying bacteria. CuNIR contains at least one type 1 copper center and a type 2 copper center, which serves as the active site of the enzyme. A histidine, bound to the Type 2 Cu center, is responsible for binding and reducing nitrite. A Cys-His bridge plays an important role in facilitating rapid electron transfer from the type 1 center to the type 2 center. A reduced type I blue copper protein (pseudoazurin) was found to be a specific electron transfer donor for the copper-containing NIR in bacteria Alcaligenes faecalis.	6.05605e-07
NC_021658.1|WP_020738431.1|9283991_9285530_+|cysteine--tRNA-ligase	gnl|CDD|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
NC_021658.1|WP_187346056.1|9271873_9272812_-|hypothetical-protein	gnl|CDD|197338	cd10283, MnuA_DNase1-like, Mycoplasma pulmonis MnuA nuclease-like. This subfamily includes Mycoplasma pulmonis MnuA, a membrane-associated nuclease related to Deoxyribonuclease 1 (DNase1 or DNase I, EC 3.1.21.1). The in vivo role of MnuA is as yet undetermined. This subfamily belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds.	3.66742e-09
NC_021658.1|WP_020738439.1|9301167_9301953_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|100107	cd02440, AdoMet_MTases, S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).	5.77677e-13
NC_021658.1|WP_044989023.1|9282770_9283550_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|227135	COG4798, COG4798, Predicted methyltransferase [General function prediction only].	2.52406e-54
NC_021658.1|WP_187345681.1|9297586_9299125_-|PilT/PilU-family-type-4a-pilus-ATPase	gnl|CDD|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	1.29099e-138
NC_021658.1|WP_020738425.1|9273267_9274410_-|AAA-family-ATPase	gnl|CDD|226984	COG4637, COG4637, Predicted ATPase [General function prediction only].	2.84272e-35
NC_021658.1|WP_020738434.1|9289122_9289938_-|arylamine-N-acetyltransferase	gnl|CDD|366312	pfam00797, Acetyltransf_2, N-acetyltransferase. Arylamine N-acetyltransferase (NAT) is a cytosolic enzyme of approximately 30kDa. It facilitates the transfer of an acetyl group from Acetyl Coenzyme A on to a wide range of arylamine, N-hydroxyarylamines and hydrazines. Acetylation of these compounds generally results in inactivation. NAT is found in many species from Mycobacteria (M. tuberculosis, M. smegmatis etc) to man. It was the first enzyme to be observed to have polymorphic activity amongst human individuals. NAT is responsible for the inactivation of Isoniazid (a drug used to treat Tuberculosis) in humans. The NAT protein has also been shown to be involved in the breakdown of folic acid.	2.06611e-89
NC_021658.1|WP_020738444.1|9312265_9314092_+|hypothetical-protein	gnl|CDD|274824	TIGR03866, PQQ_ABC_repeats, PQQ-dependent catabolism-associated beta-propeller protein. Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.	5.14901e-20
NC_021658.1|WP_148314924.1|9277095_9280974_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.37364e-75
NC_021658.1|WP_020738429.1|9281152_9282718_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	9.41532e-94
NC_021658.1|WP_020738435.1|9290370_9296325_+|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	1.40559e-152
NC_021658.1|WP_020738432.1|9286248_9288747_+|LamG-domain-containing-protein	gnl|CDD|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	1.51194e-22
NC_021658.1|WP_020738436.1|9296514_9297585_-|PilT/PilU-family-type-4a-pilus-ATPase	gnl|CDD|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	1.04638e-154

Protein sequences

>NC_021658.1|WP_020738431.1|9283991_9285530_+|cysteine--tRNA-ligase
MPLKVHNTLTRKKEPFVSAQPKIVRIYTCGLTVYAPMHIGHARTYCFWDVFRRYLEYRGYHVLSIINYTDIDDRIMQRANEREGAVDVAERNIAAFRRDCRKLHIKDYAVYTRATDFVDEQVDMVKRLIEKGHAYSVNGEVFYEVATCPSYGELSGRKVDEQEVGASGRVEEDFARKRHPADFSLWKPTSPGQPSWQTGEGAWPTGRPGWHIECSAMSTALLGDHFDVHGGGIDNMFPHHENEIAQSEPLCGRPWVRYWLHPEHLDLKEVKMSKSLGNVISVEELLSRHGHDEARWFFVTHHYRCKLPFGWDLLQQSAQGYARIKKLAAVLAEKLRGAGEEPLAPGAYASQRPEEERFPRMRHQYVHGQFKEHTERFIARFVEAMDDDLNTPNAVAAFFDYVSALYSAGIEQCDDRASLLAVYRAVARHLWVFGVEMAEPALYPALVADYAVAPSENAAGRGGDAAVDRLIAMRQAARKAKDFAKADAIRNLLAEAGVVLEDTPQGPRWTSS
>NC_021658.1|WP_044989023.1|9282770_9283550_-|class-I-SAM-dependent-methyltransferase
MKALLAANHPSAGAALRAALKSKHRVPGNAERDAARHPVETLEFFGLKPTSTVVELGAGEGWYTELLAPVLAKKGKLIVTSFDPNGPADSRNTLYGKRLKRALDKSPDLFGKVDVVVIDRDAPKLGIDGKADLVLAIREAHGWHRNGKFDTYVAEAFKALKPGGVFGIVQHRAKPDANPDESAKQGYLPEAWVIQKVESAGFKLATKSEVNANPKDTKDYPEGVWTLPPNFRLGDKDRARYAAIGESDRMTLKFVKPAR
>NC_021658.1|WP_020738429.1|9281152_9282718_+|serine/threonine-protein-kinase
MKTSSRDDEPSLAKPAADAPVAPAAGATAAGMAPTWDQRTLDTRDREGDGPGIPIAAAPRAGEYLLDGVIAEGGFGVVYRAVHATSGAPAAVKIMHAELISRADVVLRFQREVDAIGRIRHPSVVEILDVGQLEDGRPYYAMELLQGRSLEQHLFSRGRLPADEALAILDPLCSALAAVHALGIIHRDVKPSNVILCEQGGELRVVLLDFGIAKLLGTTDLSLTSSRHVVGTPAFMSPEQLLNRPVDMRTDVYALGALLYTMIAGAMPFSASAYPVLRHLHLHQAPPRPSLHAPVDPAFDDIVVRAMSKDPAGRHPDVTAFLEDVRAATARVLRTDAKEAGRVRRLAIGMLVEVLAETRALEAPTDSFLTDFEAVLPEAMTELATAGFSPLAVTSTSVLLSADWPRDERGAEEARCRAIAAALALYEQIAGPDRRDLRVGVRFCLHAGDVVVTEDGSVVGGNVLELSSCLPETAAAGVYASPAMLDGLGFTSHRATGAPGAAIPMRRVAARPPSDGAAAPA
>NC_021658.1|WP_148314924.1|9277095_9280974_-|protein-kinase
MAGAAPAIDGFSLQGPLGRGGFSDVWAAERDDDGAPAAVKVARQAASSVRERFRREAALLERVGVPHVAQLYAQGELADGRPYLAMERLFGRTLAEELAALRAPLDPDRAAGRADAILAVIEAAHARGVVHRDLKPENLFLLRASGRAVLLDFGLAKLAPGDDQPASSVRATRAGDVVGTPEYMAPEQLRGAARIDARADIYAFGVILFELLTLRPPFVGDEDAIEHGHLALRPPRPSDLADVPEGLEELTLACLAKDPGRRPDSAAALRRTLHALRARPAADTLPPPSSPRSGPRSSRPGDGVATAAAEGRQPVALLLAEAGAGPVIAAVGSRRGFVARQRGQRCLAVFSARDVHDPARAALAAARDIAERGGARVALHLASVRLRRVPGGMHAAYGSPVERPETWLPPEPWRGLAMTEEFQRALPEEALAPTPPDDPESLGEPPLLGRDDVLSALAGSATEAFDGACPGLFTLIGDAGLGKSRLTAEAASIAGVPVPDVRVVVVRALHPIHGGAAQAVRALLRVALDAPDDAPDDPRGFCAARLGEPLGGATWEAVAAALGWAEPGGGRLSGAARHGLMLALAEALRQRARRGPLAVILDDADQADDVLLDALEYATLDGEGVLLWAVVTARPRFEQARPSWGQRNQRHTRVTLAPLAEEAAMDLASRLLLPAEFPPAETLRRLADWAGGNPDCLRQIVRSLKHAGVVRRRAGGGFYLATAEVEALPPAPAWQWLAARQLDELPAELAACARVCSALGMSFDRAELEAVLDGLERAGGAGSMVDAGFGLSALVERRILLRDSEVGGGADDRHAFQNAIFQEAVYEMLDPAHRAAIHLSALAYWRAQVAAGSTDGLRALARHAAATGECAEAADAYLALGDLASARHHVVEADQRYGAALQVAAPGDARRRVRALAGRGRSRYRMCRLQEARRDFGEALALAEALGDAHQRASLLLEDATALDWDFDFEASARRVDEARPLVDAARSPELALLLRVAEGRTSWRRGKLEASIAELTDCAERAGASGDYDARVLALIMLSFQLASAGRREEAERAFGDLIALLTAAGDRFHLCAAYINRIALWAWRWSLPGAVDDLRRAVDLAREIGNPWLEKMASYNVAVLLHWSDRQREALALARRARWLEEQASERPVPHTAILLAQIHLVLDEYEQASQLALWIARSCVLEPGDVRDYALLELVLSEVGLRPAGSASLSWDEAIALARDQPIVENTLQLFYWRARMALRRGHTGEAEESLASARALRAASPMWLSRFGELERRLEEASRTDVRPTLPA
>NC_021658.1|WP_044986356.1|9276004_9276922_-|hypothetical-protein
MSSTRIVAVGVLGACVLTAGCIGSSDVEPFETAETAEAPLGRRTVAPIGANGLAPAHFWAAENRAAFRALGGAALAGGGGGVLAATPLLGTEGGRSVLDYTVRCALAEGQVVHAPNGDPYYGSFGFAPAWTGRALNLSEQRWVSACIFQHLNGSGAHVDILLRGDHPALACSPDEAPFLDFFVRDATMFGNAFLPGPIAGFACIDPDLTGELSRISLSCPLDLNLLELDRLCGHVPTCGIAFVGLCNLACTQDTAGNKTCNTLPLLGPLLGPLLGPILGPSYAETIRTQLRDADFLPLYPGCGLL
>NC_021658.1|WP_020738426.1|9274781_9275603_+|hypothetical-protein
MARYGYSFVPDRGFSAFSRDLGEGAWKDVSIKKYDTPDRMPPQLMEAPRPVAWKLRATWSIAALDEVLGIASASELAALDAEWDAAQRALHHFVASAEEGEDAAVREAATRVRAVMLKGNGTEQTRLGYDAEVDFGRSQAAAAKRTMEADLKKIGAGAHLKRIERATEALARGIGRGGGEKRLGTRAKRLRAAISGCVTAFNAIHDEITWLLAHTAPGVQRQQLEALHAPFLALLERYPPPARSGTRDDGEGEEEVATEEPADDEEEPASAPP
>NC_021658.1|WP_020738425.1|9273267_9274410_-|AAA-family-ATPase
MKLTTLRAERYRSLKHVDTSFGGLSVLIGTNASGKSNVLDALRFLSEGVRAKDFADSVADRGGVLHLAWKGEVVGEVSVETHYEDEGKRYAWTVGLRRAGGGFATWERLYQIHDGGPPGHLLEANAGKAWWYSTQAKSNRVNLALAPTACALAVASADESFPARRLGAFVQRWGFFDPSPPLLRRASNVSDADRLDTFGRNLAARLYALKKGPDGGEAFNRIVTATRRVLGVPEQLDLRESDIDGRVYFVQREPGLSYDVHQVGASSGTLRILAMMTALFGEADASLVGVEEPENHVHPSALRAFAEYLRDASERVQILVTTHSPLLLDCLPKAEEVAVVRRTQDGTTIEREQHPEAIDAALDASGFGLGEFYETKGFGA
>NC_021658.1|WP_187346056.1|9271873_9272812_-|hypothetical-protein
MAQVLKSLFGGEGPDLVGLAEIHSDGIVNELVRQLAMPLLVWEPCRNTDYAHTGLAILARKERFASLHLVTKYPDSSFSRPRFIVARCVLGERSEPFFFIVNHWRSRVEVGQSRAAEAETDRVHTAEALSTWLAQNGADTCAIVVGDFNAEPFEKPFGKPGLQAGRYFRPLVYPRLYNTARRFITEPDYCEVAVARGAAYRASRARTTLDYYDKERPVSVVFDQLLVTERAIAGGPVVLQEGTIEYAFNTIGHHLPDGDRRPTRWSFIGRVARGASDHFPLTAKFLVRTEAGHGQGRAEEEGRRAAERRGGG
>NC_021658.1|WP_020738423.1|9271530_9271935_-|hypothetical-protein
MDKDELKKKVAELLKEGAGDDLDRFRQAVGKLRELAEAVEASFTGDTVRVHVEAGHRVNYGQQYNFVVYVDKVKLRDVLFRAYVPPDGFPVTLDLFDIERPECNDVGELENKVLDFLAHKDVRARLLEIRELAA
>NC_021658.1|WP_148314078.1|9268510_9269158_+|hypothetical-protein
MLRAMTSQLRAPRLLAAALSFAALTVGWAEVGEAQMTIKRPGDRPDYKVELEPHLLFAPFEPLGPGVGTGVGAGFRATIDIVPDGFIKRINDSVGLGFGIDGLHYAGNGNYRGDCRRFENGPAGTRICTEVDAYGDASNYVFGSVVMQWNFWLHRRWSVFGEPGLSFYLGDLGRDPYPGVSPVVFIGGRFHFTENVTLTMRLGYPAFSLGVSFLL
>NC_021658.1|WP_020738432.1|9286248_9288747_+|LamG-domain-containing-protein
MRNLSFGFAHPLATKTSSAAVLALLALGAAACGSYGVDEGSLGNTELALDEAEGASIAVSVGAGGSGGSGTGGSGTGGISTGISSSSSSGVGGGTGGGPVDPPPVGPPAVGFWQFDDCSGATTELLDSSGNGTTATRSASAACAPGISGLAISFDQKKDTVSADDNPLFTFGKNLAVAAWVNPTSVSESTLQTIVQERDSGDRGFSLGIRNGEARFAVTLTDGRTVTSRAPIDANVWTHIAGIYDGRFVRLFLNGEQVGQLSAAGTIRDVNAPIHIGGNEQKQQRFTGLIDEVWLSASPTTASEIAQLSCLRRPGTITVTPASSGPVPPNTPAAYQIAVANNDVGACAPGDYALQIFSPSPGINVSGDTTFIPGVPPGSTATFAVTVNGTEDADPGVHEIPFDVLNFSSPEFLVGSGALNFELAAPTGCFVRTSREIFVKHLSVVEDPIRTTFNGPPEDPRTGAWTFARLMEDMAPTPAEAPAMVEQMLTTWLADQVVNGFTVPARPAIQQIVLDEWPRSPDGSLDLTQAPLLLLGIVNRIDVRNLAEGHAGEGRFVFGVVSQGFPQQFTIILEYKLPASTEADVLDWANDWHALGSLPFPSEEYNAALQDITSRFAGRNAAPGRPNGSSLGQLRTNEIALAGPWELREFVLSADTGFLRPETVKLTPDIGFDGSATLADFVNQNEAAIVAEQHTVPDSFQGSPFLGGSSFNNLTAWTAPGILDNEARHKFSLNTCNGCHGAAETGTPFLHVNPRSLGSEATLSGFMTGINMPDPVTGELRFLNDLGRRNQDLKALVCEPAPTFAGAAGRGGTAGAAASRSAFIRRGIGRVH
>NC_021658.1|WP_020738434.1|9289122_9289938_-|arylamine-N-acetyltransferase
MHPPAPDTASLDLDAYLARIGYRGALAATREVLDALHTAHAYSIPFENLDVLLGRPIRIDLAGVQEKLVNARRGGYCFEQNTLFVAALRRIGFKVTTLIARVRFHRSDIGPRTHMLSLIELPEGPFIADVGFGGPGLTQPIRLVEGESQAQAHDVVGLRREGDAWVLESRGREPWQDLYAFTLEEQFPVDYEVANHYTSTHPDSLFVSNVLAAISSPEARVTLRNRQLGVLRGGQVQWFELGDDELLDVLKTRFGLELPAGARLSCAGLNG
>NC_021658.1|WP_020738435.1|9290370_9296325_+|AAA-family-ATPase
MPRPDRYTLTEVLREETRYVVHRGVRNEDGCPVLLKIPRAERLDRRDVARLRHELEIGRRLSEKTAIRPRELTTYRDRPALVLEDFRGRSLDRMLGAPMELGRFLTIAARTSAALADIHAKGVVHKDIKPQNILLDPESGEVKIVSFDLASFLPEEENDGRSPGVIEGTLGYISPEQTGRLDRAVDHRADLYSLGVTLYEMLTGVLPFSAGDALEWVHCHAAVLPRPPSELVPGIPRAVSELVMKLLAKAAEDRYQSARGVTRDLERCLERLTTVAHIDPFPLGEHDFSGLFRIPKKLYGREREASALLAAFARVALRGAPELVLLAGGAGAGKTSLVQELHRTSVRGRGLFAAGKFDQRHRHVPYATLVQALRELLLGVLGASEPVVGEWRRRLSAALGKNAQLVIDVLPEVELILGEQPPAPELPLTEVQRRFEAVFRQLVGVFCRAERPLVLFLDDLQWADPESLSLLEQLVTHPEARHLLAIGAYRDIEVGPLHPLARMSERARGAGAPLREIEIPPLSTRDVQRLVADTVQASCEDSASLARLVHERTAGNPFFATQFLSMLHKEGLLEADLRAGAFRWDIGAIREKGLADNVIDLMITKIKRLSEPAQEALMLAACVGNTVDAGTLAVLRDRPAGAIHEDHRELVREGLLLRSGDTYRFLHDRVQQAAYALIPEEDRAAAHLRIGRLLSARAAADAADPRIFEIAGHLNLGSALVTDRRERDRIARLNLTAGRRAKASSAFAAAARYLAAGMALLADDAWEEEYALALELHGEGARCAFLSGDFAAAERLVGALLGRARSRLDLAEIHRIEIDLHTTRADFERAARSALACARRFGVDLPLHPARDAVERAAREVWGEIRDRRTEALARLPRMADPDAAALMLTLSTALPSAYYTDPDLYGLIACHMVRLSLRAGNSDASPPGYVAFGGTLGRVLGLYSESYRFGELARALLDAGGQAGSRAQILHMISTFIDPWIRPFRDVVGLFREAFDEAIETGALIYASYCCFHIVALRLASGDPLADVAAEAERRLTFTRRARHDAIHDIVAVLHRLVQRLRGHEPGRVGEGAEHEGARPRDAASPLTRFYERLYAAQAALLFGRYGEAVDAADAAGELLSLVTGQIQAADHGYIAALALSCHARALPEAERRALLPALRAREAELRRWAEVEPANQEDRHALVSAEIARIAGDELAAMRRYEQAIRAARANGFVQGEALAQELAAAFYRDRGFDLIADTYLGAARSSYARWGADAKVKQLDQLYPHLAARPLAATSTVTMPAEELDRLAVVKASQSISGEILMPRLEEALLRVVLAHAGAQKGYLLEAGRGAASIRARARIEGGRPFAEALAGEARAPASSAALPLSIVNYVRRTGEPVVLDDAAESRFSADEYVAQARPRSVLCMPIARRSGASAILYLENAAMRGAFAEGTLAVLELLSSQAAISLENASLYAALKKSEEQLQAIVDNSPAIIYVKDLEGRLLLVNRCFERAVQRPRDRIVGRRDHDLFPRETAERFAANDRRALEMETLLDLEEVFPQEDGPHTYLTLKFTLRDAAGAAYAVCGISTDITERKRAALAERFLAEATRRLVADLGYEATLQAIAEIAVPELAQGAALYVLDEAGALELSAVAAGSPESAGWLRALASPEGAPWAPRRALGAERAELGRVDDGVMRRWAAAAARPEALFALAPAAYLNAPLLTRDRCLGVLSLVRTGSAPPYGRADAELVEELARRAAIVLDNARLYREAQRAIQLREEFLSVASHELRTPLTPLKLKLGLLQKKLATEAADPSLERMVAASLGQVERIEVLLDSLVAVDRVARRGLDLELAEVDLAALAREVVVELGEAFSRAGCRVELDARGPVLGRVDRLRVAQVVRSLLNNAIKFGAGRPIEVTVEARGDAARVVVCDHGLGIAPEDLERIFKRFERAVSTRFYGGLGLGLYLANEIVRAHGGTIQVASQRGEGACFTVDLPRRLAA
>NC_021658.1|WP_020738436.1|9296514_9297585_-|PilT/PilU-family-type-4a-pilus-ATPase
MARIDRLFDELLNRKGSDLHLGIGYPPLVRARGELVPVRDTPLDAAEMEALLFEITTPEERRRIVDELDLDFAYSYADKARFRANYFYKITGLAAVFRTIPSKILSLDDLGCPEIIRRLSERQSGLILITGPTGSGKSTTLAAMIDHINRSRACHVLTIEDPVEFVHSPIKAQITHREVGPDAGSFASAIRSAGREDADVILIGELRTNETMKLALQLASFGVLVFGTVHTNSAAATIDRIINAFPADEQLQVRGMLSESLAAIIAQQLLRTKDGTGRVAAHEILVGSSALSAMIREGKTFQITNLMQAGRSAGMQTMDMALERLVKKDTISVQAALEKAIDKDNLQRLFPDAQGA
>NC_021658.1|WP_187345681.1|9297586_9299125_-|PilT/PilU-family-type-4a-pilus-ATPase
MREHLAPEEAQRPPPRDPDAKRPSSSELAFDLRGAPPPPAEPRAGRPSTPRFDPRGDDAPAEPRAGRPSTPRFDPRGDDAPAEPRAGRASAPPAEPRAGARPAAAGPRARPSSADVPAGALDGLLAMARDQGASDLHLVAGRPPLLRVGGELVPHGDPLDPAAVASILLPRVPARLSPVLEAEGSCDFALELAALGRFRVNIARHRRGYKGCFRLIARTIPTLASLGLPDAIGLAAGHHQGLIVITGPTGHGKTTTLTAIVDILNRETSHHIITVEDPVEFVHARGKAMISQREVGTHTRSFENALKASLREDPDVIVVGELRDTATVRMALSASETGHLVLGTMNTPSAAKTIDRLIDLFPPGDQQQVRVTLAGGLRLIVSQRLLPSADGKRMVAAAEVLPGSVALWNLIRDSKTFQIPSLQQRGKSLGIIRLDDSLAELVRAGKTTLEAALTVAEAPDELEAVLTGKRQPALAPDRRPPAPPPEASRPGAPEAGKGLFERAGALFGKKGG
>NC_021658.1|WP_020738438.1|9299768_9300299_-|hypothetical-protein
MKTLGVGLSRYSRSLVAAGAAALLSVTPFTASAEHPGATRPAAPGGAPAAAPGAESAPAAEPAATPGAGEWDSYSVEVYGMLVSRAGKVATLRPLVATSATPVAAGTKAVLFRRIEDPKGASPTKYVEIARVTMKKIEATGNMQLTIDSEQQAPAAEKGKAPGHFVKGARLKLAIQ
>NC_021658.1|WP_020738439.1|9301167_9301953_+|class-I-SAM-dependent-methyltransferase
MPTVTEHYDKLLAEHYSRMFGDHDAKVAEQRALFERLGVRPEGASEAIDLGCGSGFQSLALAQLGFRVTAVDTSDKLLAELASRRGPLPVDVVQSDLLDALERPGPPCALAVCMGDTLPHLGSKGDVEHMFAGCARRLAPGGQLVLTFRDLTRELEGADRFIPVHDSADVIMTCFLEYEPETVKVHDLVHTRGREDGRWRLSASFYRKLRLSPDWVCDRLEAAGFRVLHREIARGLVTLVARSGGGVGRDTNTGSKPCTGG
>NC_021658.1|WP_020738440.1|9301999_9302233_+|hypothetical-protein
MSERAQQTGTKDAGQAAAMSRPSRDEVQDLRRERDEARQLLITLVTALKRATFRHGTYIDGLGAAMVAVDRWSKPRG
>NC_021658.1|WP_148314925.1|9302901_9307416_+|multicopper-oxidase-domain-containing-protein
MIYALKRDVVPIDGRKPLGPGNAMLRPGKRPRPLVLRVNVGDALRVRFTNLLRPADERPDDSTATRSASVHVTGLEIRNIEALGGNIGRGPDSLAEPGETRVYELFADKEGTFLFHSGGALAGGGEGDGEQTVLGLFGAVNVEPAGAVAYRSQVTAAELAAAELPTRNPDGTPRIDYDALDEHGEPILRMLNDRDEVVHGDLNAIIAGYEESQLDSEVPVAPGRFREFTVLFHDELKAVQAFEKLEVDETFHGVRDGFGVNYGSSGFGSILLANRARLGPSKKCVECKYEEFFLSSWPNGDPAMIVERDRRGNATEALFPDDPSNVHHAYLGDPVWIRNLHAGPKETHVFHLHAHQWLKTPKDANGSPLDAQSIGPGAAFTYNVGRGGNRILTPGDSIFHCHLYPHFAQGMWELVRNHDVFEAGTRDRFLPDGEIKKGTPTPAVVPVPEIAMPPMPTYKPTVVELPGGGRKVRPPMPGYPFYIAALEGHRAPQPPLDLVVDGGLPRHVITSVPPGGAEFGRRGKFDVDIEEANIKLLPNAGTPAELAAQAFHAGRFPGATPITTTDGFPAQAYPAFTPEGEPAQFAVNGQPPAPGAPYANPCPPGAPERRYRSAFVQLDGVVNRRGWHDPQMRILVLEDDIDATLSGARPPEPLFIRANSNDCVVSEATNLFPDALEADPFQIFTPTDTVGQHIHLVKFDVTSSDGSANGFNYEDGTFAPQEVVQLINAANNLGGALKADGTVEERGRRVMLTAQRHPRIHDDRKGLQTTVQRWWANPVQNRRAEDITLNASFSHDHFSPSSHQQHGLYMGLIIEPSGSVWRDPVTGVVFGDRADGGPTSFRADIIPPRGSAQPPFREFGLAFADFALLFDECGEPVNPPTVQEAALPLAVEHRDVLAPEAISAADPGGGLINYRNEPIPLRIARRDCRTGRVEQKPGEEGEMHNVFSSRVHSDPFTPLLSAHEGDDVVVRLLQGAQEEQHVFSMHGQRWFNEINDPDSGYSNGQPIGISEHFEFGLTPSASARGDREPGDYLYQSAPTDDLWDGMWGIMRVRPRTDAALLPLPGSRDGEPREVRRFPTCPAGAPETKYVVHAITAKGNLPGDRLVYNKEFDLYDPDALLFVRAEDLPDLRAGRRAPEPLILRAAAGDCIQVTLVNELPFVLPKTPHWNYSPPIIDGFNTNQVRPSNHVSLHPQLVAYDVRTDDGANVGFNEEQTVAPGESREYTWYAGEFAQKDSRWGPVEPRAVEYGAINLRDMADVVNHGMHGAVGALVIEPRGATWRADRGTHAQAEVTFKDHYGYTRSFREFVVVYQDEVGLHSGDPRFQCVDQGLNCGTAIRNYDGEDDAEDTGHEAFNYRTEPFWARLGIPPELARVLLNEKDLSDIFSSRAHGDPATPIFTAGATQKVRVRLVQPSGHRRMHSFGLWGSAWPSNPFAEGERSRRIGENRDVLNLGIENAIGPMTHNNVVPFSAAGGRFFVPGDRLYLDQPSFKVSDGLWGIFRVTR
>NC_021658.1|WP_020738444.1|9312265_9314092_+|hypothetical-protein
MSRVERDGLSIAFELRPIPGAGGRLEARSDATAVFTITDAATGAPARDLSPLAWMTRRAGAPPDDAGCHEKIKSFMAGLISVRPDVDMNASLLWTQNDDNTLSVINSQIAFSRSKLRSLVTLAAGSTSLALHPDGSRLYVTLKNGRGLAVVDTRRSLVDANVPVGADPMRVAVAPDGRTVWVGNDGDGTVSVVDARVAEVLKTLHVGAGHHEIAFSDGGRTAWITSRDARVVTAVDTGALEPVAEIEIGEGAAAVAASDAAGAVYVANEQRGEIAILDAGRRALSSRVAVKPGVSAVQFEPSGRFAFALNPAKGEVSILDASTGALAHTLAGFASPDAIAFTDAYAYVRNLGESRVSLIELPSLQRPGKLAVVEVQVGQQAPRAAKSARSAAPFALLPEGNGAVIASPADKALYYYVEGMMAPMGTLSNYGREPRAAVIEDRTLKEVQPGVYATTVRLGEAGAYDVELLLGDRRVAACLEATVAPSAVPAEDRSPGLTVEALFDGSVELEVSKPVTLRFRATPKAPAPPLEAKEMKVMIFRFPVGFRDVALPRAEPDGAFSVTFTPPEPGQYRFMLEAESRNAPLGALPYVDLHAGSPGAAPAAGGAR

Crispr_ID: NC_021658_39

• CRISPR_ID: NC_021658_39
• CRISPR_location: 9375468-9375594
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_021658_39

Consensus_repeat	Method
CCGCTCCCCCCGAAAGCGCCGCTGCCGC	CRISPRCasFinder

spacers of NC_021658_39

>39.1|9375496|26|NC_021658|CRISPRCasFinder
CCTCGCCCCCGCTCCCCCCGAAAGCG
>39.2|9375550|17|NC_021658|CRISPRCasFinder
TGCCGCCCTCACCGCCG

CRISPR arrays and Neighbor proteins around NC_021658_39

CRISPR arrays

The CRISPR arrays of NC_021658_39

>merge|NC_021658|39|9375468-9375594|CRISPRCasFinder
CCGCCCTCGCCGCCAGCGCCGCTGCCGCCCTCGCCCCCGCTCCCCCCGAAAGCGCCGCTGCCGCCCTCACCGCCAGCGCCGCTGCCGCCCTCACCGCCGCCGCTGCCGCCCTCACCGCCGCTCCCCC

>NC_021658|39|35|9375468-9375594|CRISPRCasFinder
CCGCCCTCGCCGCCAGCGCCGCTGCCGC	CCTCGCCCCCGCTCCCCCCGAAAGCG
CCGCTGCCGCCCTCACCGCCAGCGCCGC	TGCCGCCCTCACCGCCG
CCGCTGCCGCCCTCACCGCCGCTCCCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_187345682.1|9372336_9372771_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738497.1|9380421_9386412_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_021658.1|WP_148314929.1|9364024_9365515_-|hypothetical-protein	unknown	unknown	gnl|CDD|164795
NC_021658.1|WP_020738484.1|9363495_9363951_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044989035.1|9361074_9362277_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NC_021658.1|WP_148314089.1|9387474_9388896_+|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl|CDD|225044
NC_021658.1|WP_080682772.1|9388864_9390169_-|MFS-transporter	unknown	unknown	gnl|CDD|341038
NC_021658.1|WP_020738487.1|9371494_9371992_+|response-regulator	unknown	unknown	gnl|CDD|333815
NC_021658.1|WP_020738496.1|9378892_9379999_+|P1-family-peptidase	unknown	unknown	gnl|CDD|239071
NC_021658.1|WP_020738489.1|9372816_9372972_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314931.1|9373615_9374590_+|DJ-1/PfpI-family-protein	unknown	unknown	gnl|CDD|153235
NC_021658.1|WP_020738493.1|9376165_9376810_+|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl|CDD|223399
NC_021658.1|WP_148314087.1|9375817_9376021_-|hypothetical-protein	unknown	unknown	gnl|CDD|181892
NC_021658.1|WP_187345683.1|9390976_9391570_+|hypothetical-protein	unknown	unknown	gnl|CDD|164795
NC_021658.1|WP_020738486.1|9366071_9371480_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_021658.1|WP_148314930.1|9372952_9373582_+|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl|CDD|223736
NC_021658.1|WP_020738483.1|9362386_9363322_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176114
NC_021658.1|WP_020738495.1|9377002_9378712_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|313108
NC_021658.1|WP_049949701.1|9390168_9390801_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|179115
NC_021658.1|WP_148314088.1|9386557_9387217_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020738497.1|9380421_9386412_+|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	3.19952e-152
NC_021658.1|WP_148314929.1|9364024_9365515_-|hypothetical-protein	gnl|CDD|164795	PHA00370, III, attachment protein.	6.95642e-05
NC_021658.1|WP_187345683.1|9390976_9391570_+|hypothetical-protein	gnl|CDD|164795	PHA00370, III, attachment protein.	0.000256018
NC_021658.1|WP_044989035.1|9361074_9362277_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	3.22222e-88
NC_021658.1|WP_148314089.1|9387474_9388896_+|PQQ-dependent-sugar-dehydrogenase	gnl|CDD|225044	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism].	1.43879e-47
NC_021658.1|WP_080682772.1|9388864_9390169_-|MFS-transporter	gnl|CDD|341038	cd17485, MFS_MFSD3, Major facilitator superfamily domain containing 3 protein. Major facilitator superfamily domain containing 3 protein (MFSD3) is a predicted acetyl-CoA transporter. As an atypical putative membrane-bound solute carrier (SLC), MFSD3 is most likely to be functionally active in the plasma membrane and not in any intracellular organelles. MFSD3 belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.30378e-113
NC_021658.1|WP_020738495.1|9377002_9378712_+|AAA-family-ATPase	gnl|CDD|313108	pfam09820, AAA-ATPase_like, Predicted AAA-ATPase. This family contains many hypothetical bacterial proteins. This family was previously the N-terminal part of the Pfam DUF1703 (pfam08011) family before it was split into two. This region is predicted to be an AAA-ATPase domain.	3.39845e-72
NC_021658.1|WP_020738496.1|9378892_9379999_+|P1-family-peptidase	gnl|CDD|239071	cd02253, DmpA, L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active heterodimeric form. The cleavage results in two polypeptide chains, with one chain containing an N-terminal nucleophile. This group represents one of the rare aminopeptidases that are not metalloenzymes. DmpA shows similarity in catalytic mechanism to N-terminal nucleophile (Ntn) hydrolases, which are enzymes that catalyze the cleavage of amide bonds through the nucleophilic attack of the side chain of an N-terminal serine, threonine, or cysteine.	7.67809e-151
NC_021658.1|WP_020738487.1|9371494_9371992_+|response-regulator	gnl|CDD|333815	pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.	4.84425e-21
NC_021658.1|WP_148314931.1|9373615_9374590_+|DJ-1/PfpI-family-protein	gnl|CDD|153235	cd03141, GATase1_Hsp31_like, Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein. Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein (EcHsp31). This group includes EcHsp31 and Saccharomyces cerevisiae Ydr533c protein. EcHsp31 has chaperone activity. Ydr533c is upregulated in response to various stress conditions along with the heat shock family. EcHsp31 coordinates a metal ion using a 2-His-1-carboxylate motif present in various ions that use iron as a cofactor such as Carboxypeptidase A. The catalytic triad typical of GATase1 domains is not conserved in this GATase1-like domain. However, in common with a typical GATase1 domain, a reactive Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For EcHsp31, this Cys together with a different His and, an Asp (rather than a Glu) residue form a different catalytic triad from the typical GATase1 domain. For Ydr533c a catalytic triad forms from the conserved Cys together with a different His and Glu from that of the typical GATase1domain. Ydr533c protein and EcHsp31 are homodimers.	3.56382e-43
NC_021658.1|WP_020738493.1|9376165_9376810_+|GIY-YIG-nuclease-family-protein	gnl|CDD|223399	COG0322, UvrC, Nuclease subunit of the excinuclease complex [DNA replication, recombination, and repair].	1.48197e-30
NC_021658.1|WP_148314087.1|9375817_9376021_-|hypothetical-protein	gnl|CDD|181892	PRK09478, mglC, galactose/methyl galactoside ABC transporter permease MglC.	6.55775e-10
NC_021658.1|WP_020738486.1|9366071_9371480_+|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	1.36474e-179
NC_021658.1|WP_148314930.1|9372952_9373582_+|cyclic-nucleotide-binding-domain-containing-protein	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	2.44544e-17
NC_021658.1|WP_020738483.1|9362386_9363322_-|LysR-family-transcriptional-regulator	gnl|CDD|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.46716e-65
NC_021658.1|WP_049949701.1|9390168_9390801_-|TetR-family-transcriptional-regulator	gnl|CDD|179115	PRK00767, PRK00767, transcriptional regulator BetI; Validated.	3.24472e-10
NC_021658.1|WP_148314088.1|9386557_9387217_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	2.49708e-60

Protein sequences

>NC_021658.1|WP_148314931.1|9373615_9374590_+|DJ-1/PfpI-family-protein
MTPGMTMQRTTRDGERRAMESTRGPERRGEPRGAARKAALLAGLAVLLGGSALVACAAAPPRLHPVFPERPVAEKPKGKILFVLSAAREQTLDDSSKRATGTFLGEFYEPYLALTGAGHEVVFTTEGGAVPAIDPESLDEKYWEDGALRARAQHFVERAPQVRAPLSLKQARAAADAFDGIVVPGGQGVMVDLLDNADLHALLAHFAAKHQPVGLICHAPAVLTRMRQPNPLSRRTVTSVSSLEELYIETFVMGAEAQVRNIGEQLEDHGYEHEAAFPGSAHALRDCNLVTSQNPFSTGRFSALYLEAVADYRRGARCARRERP
>NC_021658.1|WP_148314930.1|9372952_9373582_+|cyclic-nucleotide-binding-domain-containing-protein
MLGSSFMAQLSRADQVAALARMIAALDTRPAPSFDAFAALFHGKSLRKGEVFVRAGEASDSVALVNSGIARMFYTRGDGKEFNKAFVSAPDFMSVLEALITGEPARLTIQALTPMQLFVAPYARLSEFCERDIYWERVSRRIVERVYVKKVRREASLLMDTAADRYRAFVAEHGAVASRVPDYHIAAYLGITPEALSRLKRAAKRSVSS
>NC_021658.1|WP_020738489.1|9372816_9372972_-|hypothetical-protein
MNEEPSTASPELVAGPRRLVPAATRARRPGPVELLGLLTEPSRIARSRARG
>NC_021658.1|WP_187345682.1|9372336_9372771_+|hypothetical-protein
MIPVSLMALLSGCGDSDAERIEQQRETWNEKHVTSYVVETCATGFSAGCRRVAVEDGQVVAAREKSPNDNSPWSDIDDLTNVDEPIAWMFDRAEGTPDDCELSQLSFDPQFGFIREYYVSCSVEGSGERVTCFAPDTVDLAACE
>NC_021658.1|WP_020738487.1|9371494_9371992_+|response-regulator
MTTAKFSRRFRGASDVTPEEPQKERPIVVVIDDDPRMRSALAFTLRRDYDVRLYANAQEGIAGVTEMTSLVILDIRMPGIDGLTAYLKIKALYPKVPIIFYTAFQDILEKQDLLSTHKAFGYFDKNGDVSGLKAAVEKAVQHHSVVSSMASAQRLVRGIMPPDDH
>NC_021658.1|WP_020738486.1|9366071_9371480_+|AAA-family-ATPase
MLTISGYQAIAKIYESGNSVVYRGRRAGDERQVVLKLLRSDYPSQTELTRYRHEYAVLRNLEAPGVVRALDLCRHEKGLLLVLEDFGGHALAHHLQSGRFDTATFLPLAIAITLALRNVHGSRIIHKDINPSNIVFNRETGTVKIIDFGISTRLSREELSIKSPAVIEGTLAYISPEQTGRMNRSLDHRTDLYALGATFYELLTGAPPFDAKDAMELVHCHIARDPAPPRARCPSVPEALSDIVMKLMAKTAEDRYQSAAGLLHDLEACQNRLDAAGEIAPFPLGRADASGDLRIPQQLYGRTGEVKALLEAFGRVARGGTELMLIAGYSGVGKSALAHELYKPITEVRGYFVAGKYDQLKRSTPYTAITSAFRDLVRQIVAEPEAQFAEWRAKIEAALGVNGQVLVDVIPEIELIVGEQPPVQALGPAESQNRFVRVLQNFVRVFCDAERPLAVFLDDVQWADAASLRVIELLMTDAGLRGLLVIGAYRDNEVGAAHPLSAALASLRREGAIVNEIAPGPLSTEMVCRMLADALRADAAAVMPLAALVARKTGGNPFFVNEFLRTLHQTGCLRYDAGRAAWTWDVEHIESRNITDNVVELMIDKLRGLPADTQRALMSASCLGNRFDLGRLAVILEATRGDAHRRLLPALHEGLIVPLSPMEPAVPDDLAAPLVFPDYRFLHDRVQQAAYAMVDEGERSGLHADIGRLLLRSLGGRAPEEEVFDIVHHLNRGADRLSDAAERRRLAELNLLAGRRALLSAAFDAARGYFAEGLALLPAGAWRSDHALTSALHVGAAEAACMNADFGAMKELVDAALSEIHDVIEKSKLYQLLILYHHTRAEFRKAVDTSVEALAQLGETFPASPGVQDFLDAYTKTTKQVAELGFERLGRLPPMTAAPKQAALVILRRAIHASYFAAPEMLGLFICRALDLTMDHGESPLAPYAFAAFSVLVNAGVGDIATGSRFGELAIEAHRRRDEPLYKASVYNFYYGLSRHFYRPARESQAPLVEGYLSYAENGDAESAAYCLINAFVCGAVSGQNLLELESTFERYIEEVFKFKQEQVINQLSVWRQAIRNLTGRSEHAAKIKGEFFDAEQVLPGLYATGNFNTVNYIHTAQAMLYFVFGDYELAYKHAAETEPTLGASTGKVFTPLHSFYYSLAMIALYPAASPEDKERYRAKVSENQAKLKALSETCASNFLHRVLLVEAELARIDGRVAEALDLYDRAIASASEHDYVNEAAVACELAGRFWLAQGKEKLARVYLADACYHYNLWGAVRKTQDLEERYPQLAPREPLSQRSTEVAPSRTFVTTTSLGASRLDLRTVLKAAQAISGEIVLDRLLIKLMAVAMENAGAQRGCLVLRESDGLRVEAEVDWTDGREDARFPGLPLTQAASDDRPLVSAGIVQYVARTGQSVVLADASADRQFQRDDYVAQRRPRSVLCTPIIHHNDLYGAIYLENNTATGTFTQDRLELLTMLSSQMAISIENAKLYTGVEQKVRERTAELEEAHATIVRLEREAVENQMAGGFAHEMRNALSGAAMVLGTVTQGGETVCAKNAARLGELFDLLKDDIPDGKLKSVMARLGDIEEAEETLDSVLCMVGDCTARALSVTNSILEYSKLGVALAGNEVVSLRRIVESVAARHRDEFARQGVSVELDLRGGSAVVGHESHFDSIVNNIVLNARDALLLVDDGRGRRVRIEMAEEGDFQVLTVSDNADGISPDNLAKIFQPFFSTKPTTGVGLGLSFVSRIVAMYGGTIDVDSDAGRGTTFVVRLPRAVPRGQPQPASAAAGRIELNLAGN
>NC_021658.1|WP_148314929.1|9364024_9365515_-|hypothetical-protein
MGVAWSLMFATLTAGCTGESGSAASGGTGASSASGGGAGASSASGGGGGAGASSASGGGGGGGGGASSASGGGAGGDPGQGACAVTRDRIRVTEVDVGVRVINNEDEAALMPLVISPIPSGGSRLAWMSDDDRVHVVALDADDQAVGPSFGLPANDFSDLYADAEGGVLLLTRDAEGGGTLNCGAPENLCGTPPSPPIPCHDMYMVRFDGARETWATKLTSSSAALPPYSTGPTGPNVYMIWWYAHHGRIAFDGARYAGYFGAAISVSQGGCINIHQGDRMQVVDASGALQRGGFDWGCSHSGYERILWDESARKFVTVCKTDNNNRIAFAPDYKTIYPVDLAYSNLGNLVAASGGGYWLTASNIRPGQPAGSNGLADVRLLHFTGGAPDKDLVVASASGLNHRAPHLAAYGGSRMLAAWETTSRAGDIARNDPERTLYVQTRDRATGEAEGEPLEVDVLGNRYQDFVGFPDGSVAFAAPGSASTKIRVLRVLPCE
>NC_021658.1|WP_020738484.1|9363495_9363951_+|hypothetical-protein
MNTVKRFAPSAARILLGLVFFVFGLNGFLQFLPQPPAPEAAVRFGAALAATGYMFPLIKGTEVVAGALLLSNRYVPLALALLAPIVVNIVAFHTFLTPPNPVAWLVLALEVYLAFAYRAAFRPMLAARVDAGAPASAGVERGKLRPVESAA
>NC_021658.1|WP_020738483.1|9362386_9363322_-|LysR-family-transcriptional-regulator
MPSPRAAARAQSHRAPQLDEIAAFVKVAELGSFTAAAAQLGVPKSTVSRAVTRLEEGLKVRLLHRSPRAVALTDAGRRFFGDVAPHIAGLRDAALALDAYQGQPQGLIRLSAPPDGGESFVGDLLVDFCARYPLLSVEVDLSSRQVDLLREGFDLAIRATRELPDSSLVARKLFDSDVQLFAAPSYLARRGLPRAVDDLMDHERVVFLPSSRRGQWPVGDARSVRDALSTGRIATDNFQLIRSVLRAGGGIGPLPRVLAAPDLASGRLVHVLPEWSQRAGTAYLVYPSARHVARNVAVFRDFALAWVKRLA
>NC_021658.1|WP_044989035.1|9361074_9362277_+|cytochrome-P450
MTESVHTVGLLPTAREPGCPFDPPNELRQAREHGPISRYPFPGGYEGWLITGYDLVRSVLADSRFSSRKELMRHPLIDLGDMKIPPAPPGEFLLMDEPEHGRYRKLLTGKFTVRRMQLLTERVEQVTTEHLDAMEKAGPPVDLVTAFAKPIPTIMICDLLGVPYETRDSFQEHVDAIFSGVSKQDQVAGYVATQQYIAQLVAAKRANPTDDVLSDLTDTDLTDEELMGVGLLLLAAGIDTTANMLALGTFALLSNPAQWATLRARPEIADLAVEELLRYLSVAKTFQRTALEDVELGGQTIKAGTTVILSYNTANRDPERFDNPHALDIRRQAIGHLAFGHGIHVCLGQQLARIEMRVALPALVQRFPTLRLDVAAEDVDLRPETADIFGVNSLPVTWNA
>NC_021658.1|WP_148314087.1|9375817_9376021_-|hypothetical-protein
MSVAIYKLDDHVVRAADHRRERQGQGGAEPGREPESAAHPEYWQRIIKGIIIVTAVSVDLRKYLRKR
>NC_021658.1|WP_020738493.1|9376165_9376810_+|GIY-YIG-nuclease-family-protein
MSRAALLPARKGSGDEERLARLRGLVRAGAENRPGVYQMAAEDGAVLYVGQSKRVRTRLLGYFRCEPEEKGARILRETSHVAWEYCPSEFAALLAELRLIRRLWPRFNVAMKRDLKRYAFIKVTRGPAPKLHVVRGPARDPGALYYGPFTGAGRVREDDRRALARLTADVYGPPEPAAAPVPLSEIDEVQLLSSWFQRYPDELARTQPVPGLTG
>NC_021658.1|WP_020738495.1|9377002_9378712_+|AAA-family-ATPase
MPLRIPLGISDFRELREKGLEYVDKSGLLIEMIDREGTKVLLLPRPRRFGKTLNLSMLRCFFEKRPEDLSHLFQDLAVWKAGDAYRRHFQRYPVIFLTFRDVKASTFEGCWADLTRKVQALYDEHRAVLDGGALSALERRNYEAILDGTAEAALYRQALGDLSRYLHRATGERAMILIDEYDEPIHAGFVHGYAREILEFFRAILTVGLKDNPHLERGVVTGILRIARESIFSGLNNLAVYTLLQKTFSTCFGFTEPEVEALLARAGQHDAMGLVRAWYNGYDFGGTVIYNPWSVLSYLADAEPELKPYWLNTSSNDLIRATLKKHAARLGPMLEALLRGDGFETVLDENVALDRVDQSDAALWSLLVFSGYLKAEKRPRGPMAQAAHHLSVPNREVRLIYSGTFQELLEARLRDHGADLHRLLHGLLGGDAALVERQLGAFVKNVLSYHDLGADAANTPESVYQVFVLGLLAALEPGHRVRSNRESGEGRPDVLVLPNEPGQPGLVLELKVARGKRTLEQALDDGIEQVRGKDYAAELRAAGADPVHVLVIAFDGKQLRVRRADADTA
>NC_021658.1|WP_020738496.1|9378892_9379999_+|P1-family-peptidase
MDPAGGAVRARDLGVAPGIFDPGPLNAITDVGGVRVGHATVVEGDAIRTGVTAVLPHGENLYLDRVPAAIHVGNGFGKLVGATQVRELGELETPLLLTSTLSVFRAADALVEWMLEQPGMEEVRSLNPVVGETNDGVLNAIRRRPITAAHVRAALASARGGPVPEGCVGAGTGTVAFGWKGGIGTASRALPSSLGGASVGVLVQSNFGGVLRVIGAPVGEELGQHAFRAELDPDPGGGSILIVVATDAPLSDRNLGRLAARALFGLARTGSSAASGSGDYAVAFSTSASVRRPSGARRLVTTELANEETSALFQAVIEATEEAIYNSLFTAETTAGNGRTVEAIPLDRVREVLSRYGVPRRDGRSPQA
>NC_021658.1|WP_020738497.1|9380421_9386412_+|AAA-family-ATPase
MPQSSRYLVLEVLHTGADTILYRARRAEDGRPVVLKVLRRDHASPHALGRLHHEHEVARGLDAPVIVKAHGIEAFGDQVALVLEDFGGRSLDLIQRGPMPLERFFPLALRLSAALAELHRHHVVHRDIKPQNLLYNPDTGEVKITDLGIACTSPRGPEDLAHDALIAGTLAYMAPEQTGRMNRSIDERSDLYSLGVTFYELLTGTLPFQASDPVEWVHCHIALTPPPPHALVPSIPPQLSAIVLKLLAKAAEERYQSALGLQHDLDRCFAELRSRGAVEAFPLGQRDASDRFQIPERLYGREREVEALLAVFERVAARGRPELVLVSGYSGVGKSSLVAELHRPVVRERGFFLSGKFEQLKRDVPYHAFLQAFRGLVQEILCVSEEELERWRQRLREALGASGGLLAGVLPELELLLGPQPPAPELPAVEARHRFHATLQRFVAACVHEEPPMVLFLDDLQWADAGSLQLLDQLVTYAEAEHLLLIGAFRDSEVGPAHPLALMLADARRRGALVSDIVLAPLSASDVGALVAGALHAPAEQVEPLAQLVHEKTGGNPFFAIQFLMDLHQGRLIAFDAEAGAFRWDIAAIRDKGFSDNVVDLMVGKLKRLSAPAQDALKLAACLGSSLTLDTLAVVAKRPAAELSEALSEAAREGLLLRRNGAYRFVHDRVQQAAQALIPAAQLAEVHLCIGRLLLEGRSAAEREETLFDIVGHLNRGAALIRSPAERAELAALNLRAGRRAEAAAAHETAASLFAAGTALLPEERWETHYELAYDLGLERARAAYVTGSFDEAERLLAELTERARSRAERAAVVELAVALNATRGRPARAVEIGLSCLRAWDVEVSLPATDAQAEEETEAVWKLLGDRRIEGLLDLPAMTHPEIKVAMGVLRGVIIPAFFVDQNLHYLLVVRMVKLSLRHGNAETSAHAYAAFARVLAPRFGRYEEAYLFGKLAYDLADRSPVLATKASVFTLLAQQVIFWTRHYRETFSYARLGFNAAVECGDWNNACYNCIWAAAFPLLCGEPLEDVLHQTEDRMGFVRKAGYTFVHGSLLGVRYLIQALRGRPVDFPMLDGSKLDQEAFEGWLLSGAAGSARSIYFSLKAQALFVLGIPAEALAASSRLVVDYDWRNDAHALVVESFYVHALALAAVSDEASPREELPRALLDCERQLGEWAESCPPNFLHKHALVCAEIARLRGQEGEAARRYEQAIASAREHGFVHHEAIACELAAGFYRARGLSTPADAYLQKARAAYFRWGAHAKVEQLDQRYPFLVERKPIAPTVTFAVRAEQFDVLSVVKAAQSISGELKLPRLLEMLLRIVVEHAGAEEGYVLLVREDRLSTAAVIAASGGAARLLDAGEAAAALPRSILNYVRRSQERVLLDDAAARHPFSEDAYFARKQPRSVLCLPIVRQARLLGLLYLENKLVAGAFTPARLSVLELLASQSAISLENALLYSQVEQENAERQRAEQALQANQATLQAIVDNSAAAIYLKDREGRYVLVNRQAGHLVRLPRHEILGKTDAALFPGPTVGALQDNDRRVLDVGEPLECEEEVLLADGPRTFLSVKFPLGEGVMSGVLCGISTDITERKRTERAERFLAEASRRLMALGYSATLESVAQLAVPELADRCVVDMRLDPDAPGHTAAAGVPAELLDAVRDAVRPLTTAAPARSEVGDIGAAPLLGRLGVHAFLRVPLLARDRCFGVMLLLLAGPRRDYGPADLWLAEELGARAALALDNARLFAEAQQAIERRDEFLLVASHELKTPLTSLKMQAHLIERLLRRYQRSEVAPERMDAALQVLNRQIARLAHLVNELLDVTRLSAGRLTLARAPVDLAALVREVVERMSQQLADARCGVQLDLDEAVVGRWDPSRMEQVLINLLSNAMKYGAGGPIHVIVRGQPDRALLVVRDHGIGIAEADQARIFERFERAVSVRNFGGLGLGLYIVRWIATAHGGTIRVESEPGAGASFIVELPLNAAEAEPDTDGLGPARPPA
>NC_021658.1|WP_148314088.1|9386557_9387217_-|histidine-phosphatase-family-protein
MHATTKLMLIRHGETDDNRAQVFQGQAGRGLNARGREQAARLAARFAGARLRLAAVYCSDLERAEETAARLASALGLRAVADPALREVSLGAWQGLSRGEVQARFPEEWAAWRSGVDGRRGGGETYAELGDRMMRALDRIAARHAGEAVGVVSHGAAIKTAVGRMLQMDGSGLKALQVPANTGVSLIEHDPKSGYRVVVWNDAAHLGDALVEALSAPPA
>NC_021658.1|WP_148314089.1|9387474_9388896_+|PQQ-dependent-sugar-dehydrogenase
MKRQFAPLLILLLVAACGEEGGVQPADVQAGSGGSGGAPSDQGAQAGGGGQGAGGEGGSGGEGGSGGGGGSGGEGGSGGEGGSGGAGGYSPENDNTFRPEERPFSDELLEKLKTKPGFTISVFARGADNARMMELAPGGGVYVTRPTTGDVLLLRDTDGNGAADESTKVFTGGPGFETLHGIALNAERDTMYLATATSLYSAPIDGDGRLGDASTLITDLPDGGQHGKRTMRLTPDGTSLLFSVGSSCNACAETNPEHAALLLIDPSLGPQTQQDRTVFAKGLRNTIGFDWYPGTDELWGMDHGSDQRGNVVPPEELNRLVEGNNYGWPYVYSSGPGERGLDPIMDDPPDTTKQDYAAATEPAVLIYDAHSAPIDFRFYTGDQFPAEYKNDAFVAMRGSWNRYPPVGYKVVRVLFDDATHTPTGFEDFITGWLIEDGRATFGRPAGLLQMPDGSLLVSDDTSGIIYRVSYTGP
>NC_021658.1|WP_080682772.1|9388864_9390169_-|MFS-transporter
MRSPHLSWRRLGLLASLYMCQGLPFGFFTQALPVLLRKQGISLEGIGLASLLALPWALKFLWAPLVDRFFFPRLGRRRSWILPLQGLTIAALGLLALRDPGEGLSSVLAAVLIVNLLSATQDIATDGLAVDLLAPGERGLANGIQVAGYRAGMIVGGGALLVLFDRLGWGLTFALMALSIALLSIPTLLAREAACGREGARSSSVVAIATSFWKRPHARQVLALIVVYKLGDAFAVGMLRPFLTDLGLSLADIGWLLGAVGFVAGLLGALAGGALVLRLVRRSSLVGFAVLQAASVLGYAYAARAEAGVPLLAALCAFEHFAGGMATAALFTCMMDWTDRESAATDYTLQASAMVIATGVASAASGFSAGRLGYPLHFSLAAVLAALSPVLAYLLFPSARLPAKLALEEASQGQSDKHPAQAPCLTDRCTRRGR
>NC_021658.1|WP_049949701.1|9390168_9390801_-|TetR-family-transcriptional-regulator
MPRPSNTAERRAQIARALLEVMAERGYEGASIGAVAAAAHIAPGLVHYHFESKREILLAAVELLARDHEDRIERRLAAAAGDPEAELRAFIDAHLRVGEGADPRALACWICVSGEALRDADVRKAFAGALEGAVKKLAAIVRRGVRARVFSCARGDVDAAAAAIVAAVQGYFVLAATARELIPPGSAAGATWAMASGLLGLSSAARKASR
>NC_021658.1|WP_187345683.1|9390976_9391570_+|hypothetical-protein
MNSRPLSLMIAGLLSCAGLVSASCAPSSPPGDAGGQGSAGSGAGGQAGGGASGAGGEAGAGGEAGAGGEAGAGGEAGAGGEAGAGGSGPGDGESELLSGRDEASAPFRAVGRLSGGLGSGACTAFLVDPAGRPEAPAHVLTNAHCTHEWAAETAPALAARPALAARPALAGAGRGTGSPSSSRGGTRPARLSGRWAG

Crispr_ID: NC_021658_40

• CRISPR_ID: NC_021658_40
• CRISPR_location: 9436281-9436463
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_021658_40

Consensus_repeat	Method
GTCGAGCGTGCCGTCGCCGTT	PILER-CR

spacers of NC_021658_40

>40.1|9436302|72|NC_021658|PILER-CR
GAAATCACTGGCCACGACCCCCAGCGCCGAGTTGGCGATCGCGCTGGCCCCGGTGGCGGACGGAACGCCGCT
>40.2|9436395|48|NC_021658|PILER-CR
CCCTTTGAAGAAGTAGAGGTACGCGCCGGCCGCGCCGTTCGAGAGGAT

CRISPR arrays and Neighbor proteins around NC_021658_40

CRISPR arrays

The CRISPR arrays of NC_021658_40

>merge|NC_021658|40|9436281-9436463|PILER-CR
GTCGAGCTTGCCGTCGCCGTTGAAATCACTGGCCACGACCCCCAGCGCCGAGTTGGCGATCGCGCTGGCCCCGGTGGCGGACGGAACGCCGCTCGCGACCGTGCCGTCGCCGTTCCCTTTGAAGAAGTAGAGGTACGCGCCGGCCGCGCCGTTCGAGAGGATGTCGAGCGTGCCGTCGCCGTC

>NC_021658|40|5|9436281-9436463|PILER-CR
GTCGAGCTTGCCGTCGCCGTT	GAAATCACTGGCCACGACCCCCAGCGCCGAGTTGGCGATCGCGCTGGCCCCGGTGGCGGACGGAACGCCGCT
CGCGACCGTGCCGTCGCCGTT	CCCTTTGAAGAAGTAGAGGTACGCGCCGGCCGCGCCGTTCGAGAGGAT
GTCGAGCGTGCCGTCGCCGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020738529.1|9432243_9433293_-|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NC_021658.1|WP_044986367.1|9444511_9445486_-|D-2-hydroxyacid-dehydrogenase	unknown	unknown	gnl|CDD|240625
NC_021658.1|WP_080682773.1|9429038_9429308_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949704.1|9447382_9449167_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020738533.1|9443158_9444427_-|hypothetical-protein	unknown	unknown	gnl|CDD|376582
NC_021658.1|WP_020738527.1|9429858_9430980_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738536.1|9446304_9447228_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|173926
NC_021658.1|WP_148314932.1|9449276_9450104_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213260
NC_021658.1|WP_020738535.1|9445497_9446283_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381331
NC_021658.1|WP_020738528.1|9431100_9432213_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187345685.1|9440780_9443147_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379062
NC_021658.1|WP_148314093.1|9433321_9434788_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NC_021658.1|WP_148314095.1|9450677_9453950_+|hypothetical-protein	unknown	unknown	gnl|CDD|369473
NC_021658.1|WP_020738538.1|9450234_9450480_+|hypothetical-protein	unknown	unknown	gnl|CDD|378366
NC_021658.1|WP_044986366.1|9438114_9440139_-|VCBS-repeat-containing-protein	unknown	unknown	gnl|CDD|238011
NC_021658.1|WP_020738531.1|9434980_9435724_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738524.1|9428580_9428952_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_063752054.1|9423916_9425890_+|hypothetical-protein	unknown	unknown	gnl|CDD|187677
NC_021658.1|WP_020738518.1|9420874_9423691_+|cation-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319775
NC_021658.1|WP_020738522.1|9427875_9428142_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020738529.1|9432243_9433293_-|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.51889e-05
NC_021658.1|WP_044986367.1|9444511_9445486_-|D-2-hydroxyacid-dehydrogenase	gnl|CDD|240625	cd05300, 2-Hacid_dh_1, Putative D-isomer specific 2-hydroxyacid dehydrogenase. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomains but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric. Formate dehydrogenase (FDH) catalyzes the NAD+-dependent oxidation of formate ion to carbon dioxide with the concomitant reduction of NAD+ to NADH. FDHs of this family contain no metal ions or prosthetic groups. Catalysis occurs though direct transfer of the hydride ion to NAD+ without the stages of acid-base catalysis typically found in related dehydrogenases. FDHs are found in all methylotrophic microorganisms in energy production and in the stress responses of plants.	4.49877e-100
NC_021658.1|WP_049949704.1|9447382_9449167_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.60941e-108
NC_021658.1|WP_020738533.1|9443158_9444427_-|hypothetical-protein	gnl|CDD|376582	pfam01637, ATPase_2, ATPase domain predominantly from Archaea. This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family.	3.32232e-11
NC_021658.1|WP_020738536.1|9446304_9447228_-|GNAT-family-N-acetyltransferase	gnl|CDD|173926	cd04301, NAT_SF, N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate. NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.	7.96861e-09
NC_021658.1|WP_020738535.1|9445497_9446283_-|aldo/keto-reductase	gnl|CDD|381331	cd19105, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	6.73301e-27
NC_021658.1|WP_187345685.1|9440780_9443147_-|AAA-family-ATPase	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	8.06475e-08
NC_021658.1|WP_148314093.1|9433321_9434788_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	9.20312e-24
NC_021658.1|WP_148314095.1|9450677_9453950_+|hypothetical-protein	gnl|CDD|369473	pfam07705, CARDB, CARDB. Cell adhesion related domain found in bacteria.	0.000306995
NC_021658.1|WP_020738538.1|9450234_9450480_+|hypothetical-protein	gnl|CDD|378366	pfam10047, DUF2281, Protein of unknown function (DUF2281). Members of this family of hypothetical bacterial proteins have no known function.	0.000671066
NC_021658.1|WP_044986366.1|9438114_9440139_-|VCBS-repeat-containing-protein	gnl|CDD|238011	cd00054, EGF_CA, Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.	1.54908e-11
NC_021658.1|WP_148314932.1|9449276_9450104_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	9.86798e-97
NC_021658.1|WP_063752054.1|9423916_9425890_+|hypothetical-protein	gnl|CDD|187677	cd09619, CBM9_like_4, DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other domains.	4.35839e-30
NC_021658.1|WP_020738518.1|9420874_9423691_+|cation-translocating-P-type-ATPase	gnl|CDD|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0

Protein sequences

>NC_021658.1|WP_020738531.1|9434980_9435724_+|hypothetical-protein
MADPYIDPFETKIYGKFAREQMAAVLMGKVPPLDGMVEFAIGKQLVADQAMSDVLDRQPKPAPELDSGAVLDEARDVVVRFGSYLDSLKGRPVDPKVFFRGEMPSVLARRRITKLTAAVGHIADELERQREKVRGADMWLAELREVHERLGIVERQQRATRVERVELGPEVSTARDAWLGVYNANKTLVRGLLAHLGKPELLPLIFDDLAEVHRTSGVSDALPPGQPAAPPGQPAAPAAGTEPAPDA
>NC_021658.1|WP_148314093.1|9433321_9434788_+|sigma-70-family-RNA-polymerase-sigma-factor
MRSRHLGAETTTISAQPSGNFGGIYGMPRLILLGVVQSTRTEHDGPGAPPPGMPFFKCRAGSPRNWDGMGKPSRKTHGAAEGSPLTLEAIMAEHLEDIRRYLERQGFRGADRDDLVQEIFHGAARSLSRFDPQLGTVRAWLLRIAYNLTSNERKRAYRRREALWPEEALDELSSDVPDSETRLIEAQRSAVLAELLLEVPPARREILVAHDLEEAAVQDIADEHAIPRGTVWNHLRLARLSLGAAARRWRARNRGRGALLAPVAVAFGAGEARASSGPLHRGPLQRLLGWARRAFRRSPSRGEAGPAASSRRSSPVPTRGAGRSMARAATGAVAGALVLFTSGGRSDVAAPPADAVALRSPTFMTAVPRGPDRHWARALPPALPAAGAAGGGPRATGRSPSSPRHAHGPLQGGGALSTSEDRLWRQAIATLTSGRSDAARLLLERHRREFPRGVRAADREELLRWLRADVDGNGRGHPPMSSIPPRSR
>NC_021658.1|WP_020738529.1|9432243_9433293_-|hypothetical-protein
MGSTVRLLLAVAAASVVWSLAAAAAGEARPAGPSGAASARSEAEEAFAWGERARRAGRWEEAEASYRAAWQADPRPELAGELGLCELALGRFRDAAEHLRESLRDPEALQQAAKRRFSEGLRRAEREVSPATIAVSRPEAEVFIDGRRIGQGQADYFVYVEPGRHEARGKLEGYVDGVFPFEARRGLESIIGLHLEPKPPPEPAAPRAPAPAPAAAAPAAPSGPAAGTVVRFGGLALALTGVALGTGFTLAAAARGGEAAAQAEAIHRRGGLAACLYDEHAGACAALDDERSARDTLEAAAWASFIGAGVAGAVALSSFWWAPAPGSSAVRAVPLATAQGGGVVVVGAW
>NC_021658.1|WP_020738528.1|9431100_9432213_-|hypothetical-protein
MRSVLRWLAGGALLGVCALAAAGGCGGGGEYDCAEDLVCEIFNDDGTSNGHCWGRCVPDPPKPFFPPELVWTGPDLLAPSCDDLVWAVPGTTDEVVRLAPGPAAFRGWAPPSGELACPTCACTPPSCALPSEVTASAPLYTCGEGPEETRTPFAPPPDWDGACVSPGWVGPEQLGSFAIGPTRQLPCTPVVEEAPVPRDAPAVEVAVACKSSVVASLCKMPRQLCMIYQQQDHLPEGWRHCVRADGKDIPCEAPAAPGSPWPTYSEKLGVFYTAVNDSRECMPCSCKPPEMSQCEAAVSAYRDSACSEWLVGISVPREGVCVDPASDAAIGSLSATWIVNVPGTCTPEGGTPVGEPGEGAATICCLPRER
>NC_021658.1|WP_020738527.1|9429858_9430980_-|hypothetical-protein
MRSRRTWWLLRSLGALALAGLAGTLGAGGCGDDDDWPSCGQLWNPCPVVNPDGTSNGACWGKCVPRLGLASFSDPLLFWIGPEESEPSCEDLVADDRRTGRPESFVPYTFARLRSIEPGQTVCGNCVCDRGACGLPRTVAANSSSSCQQTPEATNTPFNPPRTWDGRCTSPGTVPSSQVGSIWIGPISESACEPRVQDAPPVPEGPSQVAVACLGGVIDNYCPSPIDSCMLNQQEAHVPPGWRYCTVAEEPGVRNCEAPGAPGDPPQFSDRLLFYERDFSDPRNCAPCGCVTTTPGRCEARVSAYADRACSDSALIGTKEVAGGEGDACLYVERGPALGSLSAEWEVSEQPRCTPYGGEPHPRTVCCLAKPEE
>NC_021658.1|WP_080682773.1|9429038_9429308_-|hypothetical-protein
MIELTFRVTPDDGEPRDIPVRIHEPTRNPPEKEWPWAVTVDLDGRPFTTYGMDPLNAVEHGAQHAAIVLRGGHGDALDPPLEPRTKEGD
>NC_021658.1|WP_020738524.1|9428580_9428952_-|hypothetical-protein
MRAYAAGHLLTPEALYQRRFAMDLIERTLAVLQDHYAQTGQARVFEALRGRLTGEVEERPHKEVAAALGMSVEAVKTATSRLYDRYQRTFREEVARTVARVEDVDDELRALRLALRGDPSNDG
>NC_021658.1|WP_020738522.1|9427875_9428142_+|hypothetical-protein
MTHPGVGSGFKDSWSAARYGVWYKLDTCSVLPGRWVEGEFSESGKFGKGGRWHARRVPLVELLDEERIRSLVTDPLRKKHAEVFAAGR
>NC_021658.1|WP_063752054.1|9423916_9425890_+|hypothetical-protein
MRRRTPSRRTPGAPALGSRLAALAPAALAALVALAAAAPSPALAAGAPIAAPLVESKWLKLDGVPKEWPVALTSLGVKVKGKPSKADLAAQVAIAYDDARVYVAADVTDDALRGGADHVKLVLGFPGGKVQEVALYPGQPGKSRGIVKLPGGKEAAGAKVIEAPRAGGYTLEASVPWSAFPEAATTRVGLRAGLFVHDADGAGGVDAIVGSAASEAYASLSPLATEPELAVIDGLLRSKGIRSAPKYDLVADVAGDAMRERVTVYERYLVVLGPGFRKGAQYYFEDLGVDAGEGMVPSLTARDLTGDGQAELILRKRTGSGAKYREVMHVLQFGAGDTPKPIFQHEVAISTDKGSVVNDVELVPDGAKMAIRIEPGKATRYDASNYAEGVEQTYDPLLLPWGPIKSQLYKLTGGVFTKASEQRQAPAAAARPAAARAEEPRAAAKPAGLSPAEMLDKVYALYRRDRGASSSKPRFDLGADVAGGREPERVLLHDRDLVVFGKGFRGGTGYAFMTLAQFAAPGDIRSVRALDLTGDGKAEIIVHGTVRAAAPKDAGGATVDRDVVLIFRLEGEGIQRVFAAEVGRSIGDKKIVGELKFVRANDKVGIELAPGRAVEWTEQTYPFNQDKGPVGGFEPLLLPWGGAQPVRYVWNGSAFAK
>NC_021658.1|WP_020738518.1|9420874_9423691_+|cation-translocating-P-type-ATPase
MSQAATALRRPESNTAPAAPIPVHAEEVNAFLERVGVSSSGGLSEAEAQKRLAEHGKNRLPETKKKSALVRILEQFANPLVLTLLAAATIAVVVGFTADKHESFLHRFGDAIAILLIVILNAFLGYYQERRAEAALEALQKLSAPNARVRRGGKTVVIAAEDVAPGDILELEAGDAVPADARLVQTISLATEEAALTGESAAAVKDALAPVARDAPLGDRVTMIFTGTSVVRGKGRAVVTATGVNTELGRIGEMIRSVGEQKTPLEERLDRFGAIILRVCLALSAVLLGWGFIRGGRPWHELLLEGVSLAVAAIPEGLPAITTITLALGMQRMAKRGAIVRKLPAVETLGAATIIASDKTGTLTQNEMTVRNVYAGGHRYTVSGEGYNPVGAVRDEAGAEVVDLSAPLSYLLATVALCNNASLNEDQATGRWNIVGDPTEGALLTLAAKGGQSRESVAPSHAFVHELPFDSDRKRMTVITRDERGREIAHVKGSVDVLLPLCVKFADDKGVRALSEDDRRAITAEADRMSEAALRVLAICRRVRVSRDADDVERELTFLGLVGMMDPPRQGVKEAVAECRRAGIRAVMITGDHRLTATAIAKEIGLWDEGDEALSGAELAAMSDEELARRIMHLRVFARTTAEQKLRLVRAFKAHGHIVAMTGDGVNDAPALREAHIGVAMGRGGTDVARQAADLVLADDNFATIVEAVREGRAIYRNIQKFIFFLLSSNMGLLVAVFVVSFFGKWPPLTPLMILWINLVTNGLPALALGIDPPDPKLMSEAPRPRDEGLLIKRDYLGILYVGAFMGLAAVALYATSEQTEEALLRTRAVAFSLLALSPLFHAWSCRSPVISLFGSKPLISLPLLLAVAASAAIHLIALLVPALRPVFRTYEMSSNEWMLLLVLSALIVPAVEIAKLVYRRIRPVDAGPARLPASSPR
>NC_021658.1|WP_044986366.1|9438114_9440139_-|VCBS-repeat-containing-protein
MRYRKGSLLGYLAIPAFSTVLVASCTGADPSAADGDDDEAVGEAHGALTPDHCDDFDVHGTILMCHRNGSTTYPYTILKINLLCLPAHLLHLGDYIALGDPTCHGDGCLPEGAPCDAAVPCCDGLTCHHGTCTENDECALGTDDCDANATCADTPTSFTCACNAGYEGDGVTCTNIDECAESPCQNGGTCTDGIDGYTCACPPGFTGADCETDIDECAESPCQNDGTCVDHIDSYSCACLPTYEGTRCEACEGSLADCNGLTSDGCEVNLQSDASHCNACNSACAPGDICANGGCQAAPSGQVPGTPISVPAPHSPLAPAVADVNGDGELDILVANAESGSSQTPAGSLSVFHGNGDTTVQPELYYPGAPLSSNAVVAVDVDGDGWLDAVTVDGQTNLPTSNGSISVYRNLGPSAPGTFGMPTTFTTGTPGSVHLCAGDFDSDGVADIATTSVTSSQVSVILGTGTGSFAAPALIPISGTGGVQSSIACRDLNGDGSSDLVVTSPGTARLSILISQGNGSFAAPVAYTNAASGQTAGIAFGDADGDGTLDILSNGAAGRFLFFFKGNGDGTFASGASSTASPTAIANSALGVVASDFNGDGELDAYILVTTSPGGVRPMTGNGGGGFAAGPVVPTGASPGPNAIAAADLDGDGYDDLVLTNRGSGTLTVIPNGL
>NC_021658.1|WP_187345685.1|9440780_9443147_-|AAA-family-ATPase
MKHNPAFLTPEQLRSSFVVRKRDLDIVLQYIRDSTGPSNQHVLLLGSRGMGKTTLVRMLADTVTRDPELGARWYPLVFGEESYSVSTIGELWLEAIMHLGDQTGDARWQALHDELRAERDDDRLCARALARLVGFAEEQGKRILLVIENLHMLLDEQMPKKDAWSLRHTLQNEPRILLLATATSRFGAILDEEQALYEMFATYALEPLDLAECRALWEAVGGVKASERRVRPMQILTGGNPRLLGILASFAAKTSLRHLMENLTQLVDDNTDYFKSHLESLPATERKVYVTLADLWSPSTAREVADAARMEVNQASALLHRLVSRGAVVEEGQGRRLRYRLSERLYNIYHLLRRRGAGAARVRAVVDFMVHLYEGDGLVGLLGQIAEEAKGLGPEERRDHFDVMEGIVQRVRDPELRRELILLLISRFDVLSWPDISTSLEGTLERLMRTEVERVATERDLLLEASGYAYAERYADAGAVLERLAEAEARWGTDECPSAVIAANAYLKAGRPYDAERCVRKWLAIRSKDPTVAEQLVKVLQRVGPSDQARLLREYEQAAAAGERWAWIAVAAAQYVQKNWSGVLQAYDKAKHRRITNPILTMLAWLSSVDPQSGVDSDRWQDEHQRELEPAYPWTGRVFAASGNEPMTRISGAVLLGELAGLWDETFLVVEQILSSEDDARKVADHLRDLLIAAAAAGQVDRALALLEASPARILFEPLVVALRQIAGKPVHAPPEVLEVASDLVRFVEQQRQKRQEDRSGKARASGNRTRAKARVRRPRNGRAAPEN
>NC_021658.1|WP_020738533.1|9443158_9444427_-|hypothetical-protein
MQVKAKLVREVGNWVSGDRFWNREQEVWDLKELLGEGANVLIAAPRRVGKTSLMRKLCEELEKGDYRCLFLDLQRSQSGEDAVVELGVATRPHQTLWDRAKELVRDKAERIESLGTEEFKLTFREHLKQNWQAKGERLFDALAGDDKPVVVFMDELPILVNRLLKGDEFTITPERRKLTDEFLSFLRAQTIKHRSKIRLVVAGSIGLEPVLRQAGLSATINTFTPFELRPWDDETAIGCLEALANNYSVVLLEGAARSMVDKLGSCIPHHVQMFFNHVYNDVQRRGQQEVSPEDVERVYQQRMLSTRGHAELSHMEERLKLVLGEKDLPLTLDLLTEAAVVGVLTPGASMALARDNAAAAEPGAPGEKLQDVLRRVMDVLKHDGYLVDNDAGAFVFASLLLRDWWKRRFASQFTPAAARGAP
>NC_021658.1|WP_044986367.1|9444511_9445486_-|D-2-hydroxyacid-dehydrogenase
MDRRVIACTMVFPEEAARALAEGVAPHELVLSGARSAENLAEVGRDPAVQGADVVFGQPHPDDVCAAPRLRWVHLSTAGYARYDVAAVRAALAARGAVLTTSSGVYADPCAEHALAFLLAASRRLPECLENQRGPRGWPDAAVRSRSALLRGRRVLLLGFGAIGRRLAALLAPFEVELRVLRARPRGDEPGRAVAREELGEAFAWADHVVSSLPEAEGTRRLVSAALLARMRPGAWFFNVGRGATVDQAALLEALEARRLAGAYLDVTDPEPLPPDHPLWRAPGCFITPHTAGGRREEPVAQVEHFVANLRRFERGEALVDRVI
>NC_021658.1|WP_020738535.1|9445497_9446283_-|aldo/keto-reductase
MDDWLHRAPAAFRGKRLFRLGLAANYGIDEDGVRAAMDRGVNLFLWTMRARGLGNPLREALKRRRDQVAVVGYAQVGWFGWGVRRGAEKLLRELGTDHLDVYLLSWLGVGSAWTSATERELVHLRESGKVGALGVSIHDRPRAGSLAASSPLDLLMIRYNAAHPGAERDIFPHVRDARPSVLAYTATAWRRLLKRPKGWSGPAMTAGDCYRFQLSSPHVDVALTGPRSRAEVEENLDALAKGPLTADEDAWMREFGRAVHG
>NC_021658.1|WP_020738536.1|9446304_9447228_-|GNAT-family-N-acetyltransferase
MRAIHAALVAAGAIAPLAMDDAETRAWMDCELASLVENRFFQRVDPAARGAELRAVWEPRAARDGAQLGTPHAGARYAAPYWLARGGRRVGTVALSTGARGEPLLEVSSLYVLPAHRGRGVASALLRRADGVARAHGVPGLRLTTPWAWQPAVRFYLGLRMWVAGWSDALAFVFRAGLPAHDIEIGAREAAFGVVVDGRTEHLIRASREGDRLGWVESPRMEAYRGDGADVGCLAPGTFAVALATRGYPLVRSEARWRERHRASAGGEPEGLAHKIELFEAVDRSFGFDVRTPRIPGLRYREYDDID
>NC_021658.1|WP_049949704.1|9447382_9449167_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MGQDTSLRCAGCGSPLPENARFCPSCGHPVAALDPGFAATAFPATQLGAGGQSPPPPSLPLPPVRLLPGTEISVYRIEATLGEGGMGVVYRAHDRARERVVAVKCLHSNLSGNPEIRRRFAREARVLRAWSHDNVVAVYDFVERDHLLAIVMEYVEGSTLVRHLERWRGRIPFQEIRALFGGVLDAMDEGHRMGIIHRDLKPDNILVTAGKDGLMPKIVDFGIAKILEGTTYTLSGAFLGTCCYMSPEQVKSPHAADPRSDIYSLGVTLYKLSTGQVPFDSPNHFAVMMAHVADPPAPPSSLRPDIPPALDRLILDALAKDPAGRPASCAEFRARLDEALAEFSPVTSRPSSDGRELAPTVREKTGEQMILVPGGPFLSGQQRRKVHVDAFYMDRTPVTNRQFKAFVDVTGYRPDDADASRFLSHFRRGEIPPGLEEHPVVYVSWDDARAYANWAGKRLPTEAEWEKAARGADGRKYPWGRAEPGPSRANYDNREGGTVPVGSMPAGASPYGILDLAGNVWEWCEDYDDPHFYADGPSHNPRNTRPPDKPLLVMRGGSWMYGAQSLRTWARTSFEAHYRFAGGGFRCVRTASSS
>NC_021658.1|WP_148314932.1|9449276_9450104_+|ATP-binding-cassette-domain-containing-protein
MASGGVRVRLAGIRRVFPVLDDAGRALRGSGSGVVALDGLDLDVAPGAFVALLGPSGCGKSTLLRLVAGLDRADAGTAVVEAEEGPGGPGGARARARAPIAYVFQDAHLLPWRSVLENAALPLELAGAPPEERRAAARAALLQVGLADAGARYPAELSGGMRMRVSLARAMVTRPRLLLLDEPFAALDELTRSRLDDQLRALWAELGMTVLFVTHSITEAAYLAERAVVLSPRPARIVADRTLALPAERTAALRTEPAFAREVRALQEALESGGA
>NC_021658.1|WP_020738538.1|9450234_9450480_+|hypothetical-protein
MANAIRIHTQVTSDTLHIPELSALVGKNVEVIILEEEPAPRRPTPPARKLGALRGLFDVPEDFDAPLPEDMLRGFEGDGER
>NC_021658.1|WP_148314095.1|9450677_9453950_+|hypothetical-protein
MPTCPRRIIPLALPWLLFAAAACSNPEIVNNPGQGGGGGDGGGSTSEGTGFVGTTTGSGGAGGVESGCEGVSCRPDQHCEVEDGQGTCVNNTCEDLSCDPTERCQMTPEGGATCVDISCQSDLECPFNQYCNGTICVDDTCTAGERTCDGESLLVCVSNGSTTRELFTCGGEAYFESTCTDSAAGNASCPCEDDWDCPTFAACEVGSCTGTGDAPTCLLDPVPFERVLPQIEIQWGGQNRANSNAAGSPFPTSAQNVMTPLVANLDDDNGDGLINELDFPEIIFTTFCNSVFQNSGVLRAIHGGGPSKGRNYFAVLGALVWHEGDAIDVPYTCSDATLLPTAQLAVGDLDADGVPEIVAVTESYGLQIFSNTGETRVLANNLWAEADGYNEPAPAIANIDGAGLPEIVVGQHVFTLRYDSATRELSILDRFRGDVKLMKGVQGDATRPTNPNRLGPITCIANLNDDHRLEIVAGSTAYALPRPPTGVTRRTECAPPYADAEATAFCNGQLLVVWDGQTVNGAGDGDTQIPDTRRDGFCAVADILGADQTAAPGPNNPLDQKPEVILFNNGYFFVLNGQDGTIKRRTVMGVGAQYDGGAPNVDDFDGDGFPEVGTAFGGRYVMIDLQEPTAECPAWTNPLDDNGSGAANPPRTPNGKACTTDEECSATGAATCNTQAGTCVCYHNSWLRVIEDDSSRSTGSSVFDFNGDGAAEVIYNDECFFRIYDGVTASVLFKEHSPSRTRTEYPVVADVDNDGNAEIVFATSNESGTCDAFVDSNNGLEVWGDPNDLWVSARRIWNQHSYHVTNVLESGGIPVQEPESWKSYGGRVYNTYRSNPRSYGIAPDLALSGIQISSPDAACGELTDNVEITVRVDNLGDLRVGPGVVINLYGEWDTPDVDEALHDEAGAPLQAVLQTSIEPHSSLLLTVSYSAANNAQGTLPARLRAVVDEGATERECKEDNNEETVVVDDGDALPDLQIEIGRVTDAKCNAQQVDVPTVVRNAGSAPASDVRVRYYAGDPGQGGTALHEEVVPGPIAPGQSVNLVATIDKFPWNLSILIYGVVDPDGAIDECNDGNNKDAASDKVVCERVD

Crispr_ID: NC_021658_41

• CRISPR_ID: NC_021658_41
• CRISPR_location: 9547647-9547787
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_021658_41

Consensus_repeat	Method
CCCTCTCCCGGCGCCCACGTCGCGCTC	CRISPRCasFinder

spacers of NC_021658_41

>41.1|9547674|30|NC_021658|CRISPRCasFinder
ACCGTACCCATCCCCTCCGCGGTCGAGCTC
>41.2|9547731|30|NC_021658|CRISPRCasFinder
TCCCGCGCGACGTCCTCGGTGGCCGAGCTG

CRISPR arrays and Neighbor proteins around NC_021658_41

CRISPR arrays

The CRISPR arrays of NC_021658_41

>merge|NC_021658|41|9547647-9547787|CRISPRCasFinder
GAAAGCCCCGGGGTCCACGTCGCGCTCACCGTACCCATCCCCTCCGCGGTCGAGCTCCCCTCTCCCGGCGCCCACGTCGCGCTCTCCCGCGCGACGTCCTCGGTGGCCGAGCTGCCCTCTCCGGGCGCCCACGTCGCGCTC

>NC_021658|41|36|9547647-9547787|CRISPRCasFinder
GAAAGCCCCGGGGTCCACGTCGCGCTC	ACCGTACCCATCCCCTCCGCGGTCGAGCTC
CCCTCTCCCGGCGCCCACGTCGCGCTC	TCCCGCGCGACGTCCTCGGTGGCCGAGCTG
CCCTCTCCGGGCGCCCACGTCGCGCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020738599.1|9539097_9540573_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738600.1|9540760_9541300_-|hypothetical-protein	unknown	unknown	gnl|CDD|237871
NC_021658.1|WP_020738603.1|9542135_9542363_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314102.1|9545009_9545555_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044986380.1|9556734_9559506_-|hypothetical-protein	unknown	unknown	gnl|CDD|274824
NC_021658.1|WP_020738612.1|9554261_9554837_-|hypothetical-protein	unknown	unknown	gnl|CDD|197548
NC_021658.1|WP_044986381.1|9560693_9561638_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_021658.1|WP_044989062.1|9536219_9536528_-|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|224066
NC_021658.1|WP_148314100.1|9538167_9539094_-|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|225852
NC_021658.1|WP_148314101.1|9543173_9543557_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044989063.1|9536594_9538112_+|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl|CDD|226132
NC_021658.1|WP_148314103.1|9549055_9549814_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738613.1|9555106_9555475_+|VOC-family-protein	unknown	unknown	gnl|CDD|319909
NC_021658.1|WP_020738615.1|9559641_9560694_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NC_021658.1|WP_020738611.1|9552874_9554182_+|diaminopimelate-decarboxylase	unknown	unknown	gnl|CDD|143501
NC_021658.1|WP_148314106.1|9561962_9563732_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020738601.1|9541298_9541841_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_063752150.1|9563737_9565123_+|hypothetical-protein	unknown	unknown	gnl|CDD|276808
NC_021658.1|WP_148314104.1|9550133_9550391_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738606.1|9545736_9546063_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020738600.1|9540760_9541300_-|hypothetical-protein	gnl|CDD|237871	PRK14965, PRK14965, DNA polymerase III subunits gamma and tau; Provisional.	0.00822706
NC_021658.1|WP_020738612.1|9554261_9554837_-|hypothetical-protein	gnl|CDD|197548	smart00157, PRP, Major prion protein. The prion protein is a major component of scrapie-associated fibrils in Creutzfeldt-Jakob disease, kuru, Gerstmann-Straussler syndrome and bovine spongiform encephalopathy.	0.000702487
NC_021658.1|WP_044986380.1|9556734_9559506_-|hypothetical-protein	gnl|CDD|274824	TIGR03866, PQQ_ABC_repeats, PQQ-dependent catabolism-associated beta-propeller protein. Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.	7.93578e-07
NC_021658.1|WP_020738615.1|9559641_9560694_-|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	1.35034e-23
NC_021658.1|WP_148314100.1|9538167_9539094_-|SAM-dependent-methyltransferase	gnl|CDD|225852	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	1.33665e-47
NC_021658.1|WP_020738611.1|9552874_9554182_+|diaminopimelate-decarboxylase	gnl|CDD|143501	cd06828, PLPDE_III_DapDC, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase. Diaminopimelate decarboxylase (DapDC, EC 4.1.1.20) participates in the last step of lysine biosynthesis. It converts meso-2,6-diaminoheptanedioate to L-lysine. It is a fold type III PLP-dependent enzyme that contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain, similar to bacterial alanine racemases. DapDC exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Homodimer formation and the presence of the PLP cofactor are required for catalytic activity.	1.88765e-141
NC_021658.1|WP_044989063.1|9536594_9538112_+|sigma-54-interacting-transcriptional-regulator	gnl|CDD|226132	COG3604, FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms].	8.83534e-125
NC_021658.1|WP_020738613.1|9555106_9555475_+|VOC-family-protein	gnl|CDD|319909	cd07245, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.15442e-23
NC_021658.1|WP_044986381.1|9560693_9561638_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.22631e-97
NC_021658.1|WP_148314106.1|9561962_9563732_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.31359e-88
NC_021658.1|WP_063752150.1|9563737_9565123_+|hypothetical-protein	gnl|CDD|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	3.28156e-05
NC_021658.1|WP_044989062.1|9536219_9536528_-|4Fe-4S-binding-protein	gnl|CDD|224066	COG1143, NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion].	1.50863e-07

Protein sequences

>NC_021658.1|WP_020738606.1|9545736_9546063_-|hypothetical-protein
MVLAATGFGVGAIGLGVGAVAGALTLARSGALAEACPDDRCPPSRRDELGAANTLANVSNAGFAVLAIGAGVGVAGLLMLPAQGSPPRARAALTPVLGPGVIGLRATF
>NC_021658.1|WP_148314102.1|9545009_9545555_+|hypothetical-protein
MRSIFCGATFLMVIAASMTGCAIEQADMLDDAMGEDTEMVDSSAAAVGIDEGPGEAAISAPPSADPGAELGLVAGPGQSYIPQIGQLPPTKFVPPSKCALPSKCAPPTKFVPPTKFVPPTKFVPPSKCAPVFTQHQVTKQFPSCVQFPTYVQFPSLVQLPSPVQFSGPAQFPTAPPLYPQR
>NC_021658.1|WP_148314101.1|9543173_9543557_+|hypothetical-protein
MRSIFCGAAFLMVIAAVTTGCAVEQADTYDSEVSEDAEVVDSSAAAIESEVGGSRVGIDLVAGPGQSYVPQIGQMAPKKELCLSKHGLPTKLVPTITQYPGTTQYPGTTQYPGIWQYPTNPPIYPQL
>NC_021658.1|WP_020738603.1|9542135_9542363_+|hypothetical-protein
MDPLRANADSRAESTAEGGRGLADILGASSAPLARPESANIKTAVRTSRRVADFMFVYLYERVLSGKLSEHLRIM
>NC_021658.1|WP_020738601.1|9541298_9541841_+|hypothetical-protein
MEIDASIVHAGARSLHVKPGMSGYDWRMLSVPAPGPTFWVRLYVRSSVDLGQSDHNAYFQAMTGTGEPNEGDNVEVAEQYCQIVLNLRDDVVLPTGGDFRCGSGGASLPKDQWHCMEAYFDGTKGDVQIYANGTKIIDKTGWKKLDFKTFSFGYLGFHGPARSMWYDDVAVAPERIGCAD
>NC_021658.1|WP_020738600.1|9540760_9541300_-|hypothetical-protein
MFFSASAAWYDGRYVAPAGSPSPSKSAQNVAVAGHAPVGVPVPVLDVVLVALGVPVLLLVVVLLLVVVLLLVVVLLLVVVLLLVVVLLLVVVLLLVVALLLAPPPALLLVAMGLPVPELTLDAPPVPAPEPPAPPASEPPFPSSEHPAAAADRARQETPTQVKRAMSRCKEEVMSMPER
>NC_021658.1|WP_020738599.1|9539097_9540573_+|hypothetical-protein
MPGLAVGRPGSSAAAPQRTCHVAGAPVCPPFGSRSAPGRSLRRARPASARCRCGDPRRGEPRARRRGTGRSSRLGCAEGETPESEAGSYLTDAELAACLPSIKAELGDDIQGYTVTNAARDVGEIIARTRAPGGDVIVSGGSYGSIWGHRYLQLYPDQPTAVSLTALAVNSRLSDMDVWLNDLGQRFMGLCGADPSCSEKLGADPWATMTETLDAFEEGACPEVAALGVDRPVFQALFAQSLYQWAPRPLIPALIYRLDRCSPADVAAFTHLAGILLAPLPEPLSPSLRFYSPVLRNNIMLSELWADPPPPASEMQEYLAEANVALGLTDDAAAVHESWPRYTPDAYAGQWATTSVPLLLLHGGLDFIPSAVPEAVERHFTGPNQTFVMLPRAPHTLESPTSSGTSCDLEILLQFVADPEAPLDTSCTERILPLDFSVDPTLSATYLGTDDAWDGDPGAERRASTASPEHARAITRLREAIARLRAAIAAR
>NC_021658.1|WP_148314100.1|9538167_9539094_-|SAM-dependent-methyltransferase
MRSRRPSLTASLVAALRALYTEMPEPYRVAPDPLAARLVPWPLALPARALPRAAGSPAAARALHRAIGVATFGVGYHVALRTRAIDDALREAVARGTSQLVVLGAGLDSRAMRLPELAGVQVFEVDHPSTQRDKVERLASLARGDGSAAGAPGAARAAPALEARGLARVPVDFERDRLDEALLAAGFRPAEPTFWIWEGVAVYLTREAIEATLRLTAALSAPGSRIALTYGMLPGAELPAWAERAIRGLFRSLGEPVRTPLAREEMRELLAGAGLRVLSDESTVDWAARYWPPHRGVRAIERLAVAER
>NC_021658.1|WP_044989063.1|9536594_9538112_+|sigma-54-interacting-transcriptional-regulator
MPAPRAALSRACAGLVRPWQRPYGAAQRHFGGVAPRPMTAPADRALLLLADLGEAAARAHTEATLVPAVSAVLARHLPLRRLDLRRGAGAPGAPEIRRGAGGEAVAVFALRDAEGAVGCAAMELGEGAALDLSPALLEALGRLLAVALRQVQVLGRVAAIARRAQGEKRALQEELDRVALPREVVARGPAMRAIFLEMVPLVARQDTTVLVRGETGTGKEVIARRIHALSRRAERPFLAVNCGALPEGLVESALFGHERGAFTGAAARHLGTFERASGGTLLLDEIGELPRAAQAKLLRVLQEGEIERVGGEGAVRVSVRVIAATHRPLEAMVASGAFREDLYYRLQVFPIVVPPLRERPEDLEPLTRVIVEKVAASFGRRPPRVSAEAMARLRAHDWPGNVRELENVIERSMVMSTGDELVLSAPLAAAPRAAGRAMTYREAAQRCIEDALRASGGKIYGEDGAAAALGLKPTTLQSKMRKLGIRREDGGNGGNGGNGGNGGNR
>NC_021658.1|WP_044989062.1|9536219_9536528_-|4Fe-4S-binding-protein
MAYVIAEPCIATCDTACVSVCPVECIHGPLPAGEIARIAELPEGERKTRLARLQLYIDPESCISCGACEGECPVDAIFDEDELPAEWQHYREINARFFAQRA
>NC_021658.1|WP_148314103.1|9549055_9549814_-|hypothetical-protein
MRALAVRGALALLVGLPAAGCQLVSGIDAMDVDESAGGVVGDCGPVGERCGGTCEEGIVTPPGTCTDDGTCSAEPSSCGSYDCDLSGTACATSCSIFKGCVDRAVCDTMSATCMACGASPPDPAPCDGCERCEGGKCITRCDTEGECVRDRMLDAKERPARLECNDQCNNIRVVCIGPYPCEVVCGDGGCQGLLMQCSHDGPCYLECSRSGCASNVKFVCGANTCLAACILETTIVDQVCESSCSCMSQVCQ
>NC_021658.1|WP_148314104.1|9550133_9550391_+|hypothetical-protein
MPYFAFRNFPDDTPIPDDCYSCDGSPDWAALLEWICPNLSRDEAERLAAVGETSGDRPDVVGLKRLIEAHARPAPHGAERPDATT
>NC_021658.1|WP_020738611.1|9552874_9554182_+|diaminopimelate-decarboxylase
MQEAEIKIGGISVRDLAEQYGTPLYAYDAERIRENFRRLTRALRSCYPEVSVFYAIKACNNLEIAKLLVEQGSGVDAASPNEIRLAQALGLSGEQIIYTGNSLSDEDLAAGLRAGVIFNVDDHGILRRLFALGRPRCMSFRINPSGEDIATPDLKPFAGPSAKFGIHPRYVEDAYRTALENGVERLGVHMMPHSQANKPESFAHVTAKLLDLIGPVARKLGFDLAFLDIGGGLGIPYRREQPALDVDAVAREIAAVVQKKCAEHGMKAPRLVMEPGRYFVGDAGYVLGRVISIKQGYKTIIGTDISMNTMARPVMYGAYHEVRINGRRGKTAPMAMTGQVCENTDMWISERELPADVAEGDVVVLMDAGAYGHVMSYDYNGRLRPAEVLVDGGKSRLIRRRDTFEDMVSRMCLSDDINERLRTMGVDPAGAAGRG
>NC_021658.1|WP_020738612.1|9554261_9554837_-|hypothetical-protein
MAESRKIMLLAASLSAAIAGCMAATDEGDGREAPSAALAPADVEESVGEASAAQHCHGCPPGTTYVAVVNTCVSEPARFDATPGAYGCRYGAILTGRGNVICLPASEWGPVPPPVVAIGGGLPGPQPGAWPPPGGGLPGAWLPPGGGLPGPQPGAWPPPGGGPPGPQLGEWPPPSTGLVAPVPQDPLAPFP
>NC_021658.1|WP_020738613.1|9555106_9555475_+|VOC-family-protein
MPFTFVCIDHVQLAMPPGQESRAVAFYRDVLGMEHVPKPEPLASRGGAWFRAGAVAVHLGAEHDFRPARKAHPGLVVKGIDDVAAALEAAGHAVRWSDELPEVRRFHTDDPFGNRIEIIDGG
>NC_021658.1|WP_044986380.1|9556734_9559506_-|hypothetical-protein
MPPSRSLRLLLAVSSSVTAMLLVAALPAAAATSFTTFESGQVRPLALSANGKLLFAVNTPDNRLEIFRVQADRLRLEASVPVGLEPVAVAARGDDEVWVVNHLSDSVSVVDVRDAERARVIRTLLVGDEPRDIVFAGPKRSRAFITTAHRGQNVPFDPQITTPGVGRADVWVFDARQLGTSLGGTPLSIVTLFSDTPRALAVTPDGSRVYAAAFHSGNRTTSIDESLVPNGGEAAGGLPWPNTNSEGVPQPEVGLIVKFDGAHWVDELGRPWDDMVRFSLPDKDVFVIDAAANPPRQVDGPGGFFTGVGTVLFNMVVNPVNGKVYVSNTDARNERRFEGPGLFAGHSVRGHLHESRITVLGPDGVVPRHLNKHIDYSSCCAPVPNEESEKSLAQPVEMAVTRDGATLYVAALGSDKIGIFDTASLEDGTFVPSRANQIPVPGGGPTGLVLDERRRRLYVLTRFDNAISVIDTRTRREVAHVPMHNPEPPSVVRGRRFLYDASLSSSHGDSSCASCHIFGDFDSLAWDLGNPDGAVLDNPGPFCTELFGLDPSLHPMKGPMTTQSLRGMANHGPMHWRGDRTGGHDEPTSQPDSGVFDERAAFKKFSGAFVDLLGRDQTISEEDMEDFTDFILQVTYPPNPIRALDDALTPDQLAGRAFFGGPVSSILGASCIGCHVVDPGANPDDLAPGFFGSDGGSANANESQVFKVPHLRNQYQKVGMFGMAESFVFPFGGSNAHMGDQVRGFGFLHDGAVDTLFRFNSFSDFVQTPENPGGFAVGPEGDLLKHQVAAYMLALESNLKPIVGQQITLTSSNAAATGPRVDLLVARADAGDCDLVVKGRSQGAELGFLYLGNGWFDPDRASEPWRSDAELRLLATGRRGELTYTCVPPGSGERIGIDRDGDGFRDGDERDAGSDPADPNRVP
>NC_021658.1|WP_020738615.1|9559641_9560694_-|ABC-transporter-permease
MARGFRSLRGSPLALLIRARVVEFLREPEAIFWMLVFPILLSSALAVAFGGRAEGPLPVSVEAGAGAEARRAALEASGQVAPRVVPREQAQRELRTGKVALVVLDTDPPTYWFDPTRPESRAARLEVDEALQRAAGRADAFRPAALEMTEKGSRYIDFLVPGLLGMNVMSTGMWAIGFSIVQQRIGKLLKLFVAAPMKRWQLLVAHLGARLVFLAIEVVALLLFAVLALGVPIAGSLAALALVIVVGALSFVGLGLLVASRPRTLEGVSGLTNLAMFPMWIFSGVFFSTERFPAAMQPFIQALPLTALNDALRGVMLEAAPLAALAPELALLAGWGVVCFALALKLFRWQ
>NC_021658.1|WP_044986381.1|9560693_9561638_-|ABC-transporter-ATP-binding-protein
MRSVSAPPALVCRGLIKRYGDVVAVNGLDLEVRRGECFGLLGPNGAGKTTTVEILEGLTRADAGDVEVLGERWTGDGIALRRRLGIQLQETRFPDKLRVGEVIALFRSFYPRGLDPEEALRRVSLQEKAGAFVRGLSGGQKQRLSLACALAGDPEVLFLDEPSTGLDPASRREIWDIVEDLKARGRTILLTTHYMEEAARLCDRVAIVDRGRLLSLGTPAALVASLGAEHVVEIEVDGALDEEELRGLPGVEAVRSAQGALRLTVRDVARVLPPLLALCAARGAAPRRLATHHASLEDVFMALAGRKLASEEAA
>NC_021658.1|WP_148314106.1|9561962_9563732_+|protein-kinase
MVSDEEGVVPVHCGEVIADRYRVERLLGIGGMGAVVAARHLSLGELVAIKFMRAEHCGNAALLRRFQREARGMFRLKTEHVPRVYDLGAIAPRAGVALPVPYIVMEHLSGNDLRSIVERRGRLPVDEAAEYVRQACVALMEAHALGMVHRDLKPANLFLTYRTDGTPLVKVLDFGVAKFTCARPEEDGLEMTTARSVMGSRRYMAPEQMLTPKDVDLRADLWALGVVLYQLVSGALPFGAETLEQLVLVVSEQAPRPLRSACAELPEGFEEIVMGCLEKNRARRPASARELAAALSPFALRGPPDATLPTAVHRSQPTYTWLDDGPPTSAVRPPTTAIRPSEAPGSGVRRPRRAWLAAGAFSASAALAATVAPPGWPRSAEVAWSDGGSAQHLAGMPQGLAGMPQGLAAGPLGTTAADGALLAPRAAGDGALHGGDGAACGAPETDVGAVLPDVCGGAGAVAPARGAPHGRAGAGRPPRAAARTALVAGAWVGPAPQGRSERQEPPAASGDAPSAGRDGTSRRSGSTEAPSPAARAVGAAGAAGTAAAEPAAPVPPSGPGTAAGAPIPVAAPGRGAEAPPSAGPQDSPW
>NC_021658.1|WP_063752150.1|9563737_9565123_+|hypothetical-protein
MCRGALRKVSCSRPRELACALAALSLLLSPASGTAAAPGLGHPNPGQPNPGSSGLGHPNPGQPNPGSSGLGHPNPGQPNPGSSGLGHPNPGQPNPGSSGLGHPNPGQPNPGSSGLGHPNPGQPNPGSSGLGHPNPGQPNPGQLGAHKEQVLALYQAARQLLDAGRVAEACAVLEQGRTLDPTAINLLLRLGECLARAGRTAGAWNVFSEAAAVARSAGDPRAARAAAIAAALEPRLSRITIDVPAATAAPGLEIRRDGVLIPPAQWGQALPVDPGTHTVEARAPGRRRWSTVRAVPPDGARELVHVPTLEQEPPPHAPSAALPGPRGQAPRLLASAGRSDGDGGGRAQRVIALASGGAGLVGLGLGAAFGLEAIARRDASNRGHCDARSRCDAAGVALREDAQAAGTASTIAFSAGTAALLAAGLLFWTAPPKAAAPPARRAAAAATAGPGAFSLVVGGSY

Crispr_ID: NC_021658_42

• CRISPR_ID: NC_021658_42
• CRISPR_location: 9815196-9815386
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_42

Consensus_repeat	Method
CTGGCTCGGGCGGCGCGAGCGCAGGGGCAGGCTCCGGCGAGGGCGGG	CRISPRCasFinder

spacers of NC_021658_42

>42.1|9815243|97|NC_021658|CRISPRCasFinder
TCCACCGCCAGCGCCACCGCGACGGCTGGCTCGGGCGGCGCGAGCGCAGGGGCAGGCTCCGGCGAGGGCGGGTCCACCGCCAGCGCCGCCGCGACGT

CRISPR arrays and Neighbor proteins around NC_021658_42

CRISPR arrays

The CRISPR arrays of NC_021658_42

>merge|NC_021658|42|9815196-9815386|CRISPRCasFinder
AAACGTCCTCCGGCGCGAGCGCGGGGGCAGGCTCCGGCGAGGGCGGGTCCACCGCCAGCGCCACCGCGACGGCTGGCTCGGGCGGCGCGAGCGCAGGGGCAGGCTCCGGCGAGGGCGGGTCCACCGCCAGCGCCGCCGCGACGTCTGGCTCGGGCGGCGCGAGCGCAGGGACAGGCTCCGGCGAGGGCGGG

>NC_021658|42|37|9815196-9815386|CRISPRCasFinder
AAACGTCCTCCGGCGCGAGCGCGGGGGCAGGCTCCGGCGAGGGCGGG	TCCACCGCCAGCGCCACCGCGACGGCTGGCTCGGGCGGCGCGAGCGCAGGGGCAGGCTCCGGCGAGGGCGGGTCCACCGCCAGCGCCGCCGCGACGT
CTGGCTCGGGCGGCGCGAGCGCAGGGACAGGCTCCGGCGAGGGCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_080682437.1|9822458_9824240_+|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|226119
NC_021658.1|WP_148314946.1|9815389_9816484_+|pectate-lyase	unknown	unknown	gnl|CDD|312856
NC_021658.1|WP_044989105.1|9797889_9799734_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020738794.1|9810425_9812840_-|hypothetical-protein	unknown	unknown	gnl|CDD|374209
NC_021658.1|WP_148314135.1|9796530_9797673_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080682776.1|9819749_9820346_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NC_021658.1|WP_020738787.1|9793786_9794425_-|hypothetical-protein	unknown	unknown	gnl|CDD|226106
NC_021658.1|WP_020738791.1|9802656_9804186_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044986411.1|9820395_9821175_+|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NC_021658.1|WP_049949893.1|9816581_9818207_+|family-43-glycosylhydrolase	unknown	unknown	gnl|CDD|350116
NC_021658.1|WP_080682436.1|9794440_9796126_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_187345692.1|9819082_9819676_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187345693.1|9824294_9825797_-|hypothetical-protein	unknown	unknown	gnl|CDD|240291
NC_021658.1|WP_020738803.1|9821241_9822135_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738790.1|9799993_9802648_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NC_021658.1|WP_044986410.1|9808058_9809837_-|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl|CDD|379079
NC_021658.1|WP_020738796.1|9813577_9814972_+|hypothetical-protein	unknown	unknown	gnl|CDD|214765
NC_021658.1|WP_148314947.1|9826034_9827396_-|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271177
NC_021658.1|WP_020738792.1|9804313_9807955_+|VCBS-repeat-containing-protein	unknown	unknown	gnl|CDD|173810
NC_021658.1|WP_020738807.1|9827782_9828187_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_080682437.1|9822458_9824240_+|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|226119	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism].	1.28423e-10
NC_021658.1|WP_148314946.1|9815389_9816484_+|pectate-lyase	gnl|CDD|312856	pfam09492, Pec_lyase, Pectic acid lyase. Members of this family are isozymes of pectate lyase (EC:4.2.2.2), also called polygalacturonic transeliminase and alpha-1,4-D-endopolygalacturonic acid lyase.	6.58192e-133
NC_021658.1|WP_044989105.1|9797889_9799734_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.74321e-105
NC_021658.1|WP_020738794.1|9810425_9812840_-|hypothetical-protein	gnl|CDD|374209	pfam15902, Sortilin-Vps10, Sortilin, neurotensin receptor 3,. Sortilin, also known in mammals as neurotensin receptor-3, is the archetypical member of a Vps10-domain (Vps10-D) that binds neurotrophic factors and neuropeptides. This domain constitutes the entire luminal part of Sortilin and is activated in the trans-Golgi network by enzymatic propeptide cleavage. The structure of the domain has been determined as a ten-bladed propeller, with up to 9 BNR or beta-hairpin turns in it. The mature receptor binds various ligands, including its own propeptide (Sort-pro), neurotensin, the pro-forms of nerve growth factor-beta (NGF)6 and brain-derived neurotrophic factor (BDNF)7, lipoprotein lipase (LpL), apo lipoprotein AV14 and the receptor-associated protein (RAP)1.	1.62626e-05
NC_021658.1|WP_080682776.1|9819749_9820346_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	3.08588e-25
NC_021658.1|WP_020738787.1|9793786_9794425_-|hypothetical-protein	gnl|CDD|226106	COG3577, COG3577, Predicted aspartyl protease [General function prediction only].	0.00570165
NC_021658.1|WP_044986411.1|9820395_9821175_+|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	1.98967e-06
NC_021658.1|WP_044986410.1|9808058_9809837_-|right-handed-parallel-beta-helix-repeat-containing-protein	gnl|CDD|379079	pfam13229, Beta_helix, Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.	1.70037e-09
NC_021658.1|WP_080682436.1|9794440_9796126_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.82021e-67
NC_021658.1|WP_148314947.1|9826034_9827396_-|tyrosine-type-recombinase/integrase	gnl|CDD|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.11672e-12
NC_021658.1|WP_187345693.1|9824294_9825797_-|hypothetical-protein	gnl|CDD|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	1.03278e-08
NC_021658.1|WP_020738790.1|9799993_9802648_+|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	9.27808e-49
NC_021658.1|WP_049949893.1|9816581_9818207_+|family-43-glycosylhydrolase	gnl|CDD|350116	cd09002, GH43_XYL-like, Glycosyl hydrolase family 43, beta-D-xylosidase (uncharacterized). This glycosyl hydrolase family 43 (GH43) subgroup includes enzymes that have been annotated as having beta-1,4-xylosidase (beta-D-xylosidase;xylan 1,4-beta-xylosidase; EC 3.2.1.37) activity. They are part of an array of hemicellulases that are involved in the final breakdown of plant cell-wall whereby they degrade xylan. They hydrolyze beta-1,4 glycosidic bonds between two xylose units in short xylooligosaccharides. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	4.30876e-173
NC_021658.1|WP_020738796.1|9813577_9814972_+|hypothetical-protein	gnl|CDD|214765	smart00656, Amb_all, Amb_all domain.	2.14135e-24
NC_021658.1|WP_020738792.1|9804313_9807955_+|VCBS-repeat-containing-protein	gnl|CDD|173810	cd07484, Peptidases_S8_Thermitase_like, Peptidase S8 family domain in Thermitase-like proteins. Thermitase is a non-specific, trypsin-related serine protease with a very high specific activity. It contains a subtilisin like domain. The tertiary structure of thermitase is similar to that of subtilisin BPN'. It contains a Asp/His/Ser catalytic triad. Members of the peptidases S8 (subtilisin and kexin) and S53 (sedolisin) clan include endopeptidases and exopeptidases. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. Serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of subtilisin. The serine residue here is the nucleophilic equivalent of the serine residue in the S8 family, while glutamic acid has the same role here as the histidine base. However, the aspartic acid residue that acts as an electrophile is quite different. In S53 the it follows glutamic acid, while in S8 it precedes histidine. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. There is a great diversity in the characteristics of their members: some contain disulfide bonds, some are intracellular while others are extracellular, some function at extreme temperatures, and others at high or low pH values.	6.08774e-30

Protein sequences

>NC_021658.1|WP_020738796.1|9813577_9814972_+|hypothetical-protein
MTNPDINWRESSLKSDQEIVRCLAETLGRPVGYGEKALGGFDPSGNSRLTVITTRSDVSVEQQIYDAVTSDEHNWVVFDKDDFKSDRDIAMYRLKCGEPAVLAKLGATEQQCVNYQEWCSAKGVPAAACEHQFFNVALNDASLPIRNVVIGSNTTIDGRMSRAAFRFSGFAIGRDSTGTPTQTAESVILTHLSFKGAGHVEDHGLDPDMIRSTGASHDIWIHKNSFSFTGDSAFDVKVGAHDITMSFNRVLDVKRATLHGSSDDHTIDAQITTTMHHNAFITSAPFYDEGRGTARRVPLLRRGSSHMFNNVFMNYYKDFASVRVGGTLLFEDNVFLGGTPVQSEKSDRGAAFDEWTTKRLSNNVVDDGNFTATGSFAWFSDDECVIDPTYEAAVPGGGGAARDLSQDYSEESRALIGMHKLRAGQDLVDYVNATAGKDGAVPFNSPLSEGRDAILALPHEACIR
>NC_021658.1|WP_020738794.1|9810425_9812840_-|hypothetical-protein
MSIEVGAVACIRRMTSLLAVGAGLLAGGCAEVSTGEPAALGSARLASSALGADRTEERRHHGHGSGGARGRWRSRGVGGGGALFSPSINPHDGREIFMASDMRGVYRTRDFGRKWTNLDFRNIQGGVLSQFRFTADPDVLYAVTYKGPENVIFDAATLAKSTDGGATWEAPVTTPGAPGDAHYLFVDPCDTERLLVSDTRQLYASRDGGRSFHLVHTTDWPGGLRVGGVHWDGDDIYAGTSDGLLVSRNGGASFALDTSIGGLPQGEKIVSFAGAGHGRRARFFAVTFSAADSAGNPLVTANTTGGELDAYAGLYRLKLGERRWIPATNGLGPSDKLAFVATSADDPGVAYAAGGDRQTLAPIVLKTVDGGASWRHVFRSDHNANIATGWSGFGGDMGWDFGEYALGLSVSPEDSRRVAITDLGFVHVSDDGGKSFQQAYVDPADDNRRGADTPKSRFYRTSGVEQTSGWWLTFPDKDTIFASLTDIRSAYSEDGGRSWARDGANGLTLNTTYHAVQHPITGALYAATGSVHDIYQSPWMRDARIDGTQARPARGGIMVSHDKGATWSLVADLGRNVIWLALDPNDPDQLYASTVHSQTGGIVHLDLSAPGAAPEPLPAPPRTQGHAFNVHVLKDGSIVATYSGHQPGNTRTFTDRAGVFLLPPGASAWEDRSSPEMHYWTKDVVIDPNDRTESTWYVTVFSHDDRFFGGLYRTRDRGLTWQRISDKVRVESCAIDPRDPDRMYMTTERDGLWITEDLNDDAPRFFRDDGYSFQQPVRVFWNPHDLDEVWTVSFGGGMRVKRER
>NC_021658.1|WP_044986410.1|9808058_9809837_-|right-handed-parallel-beta-helix-repeat-containing-protein
MSLDQRFVKIWIGVLLALVSAPAGATPPPDSAGCDEAGWGGRPDAMESAASRDFCDLDAPYTEPPFAADETTGVACPDAAALSPVCTGPFCPASGGCRGTRTLHEDLNACQGARCCLPGSVDPDGVVDVLPYLARPAEWPFSADASVDHSTNVDDSPGIATAIECAASLRARRRVVAFPAGRYVLRSPLRPHYDALTLEGPELSPHAGPGDPGTATLVAIPCNPEQYPGAIQVTGVAKRDGTTVSAVRGLWIRNLQIALTDGPRRTANSGIHLNTCADCKVENVIVRYAPLVPQLPACKPSNLEGIGFSWGSGGVIRNVIVDGTSKGGIYLSSIAGHHDTPPILVENCEIKNINGPIGASAIKIITANVTVRNCNVHHNLIHPSDGSATGNGGHGLWISAQVPPGPGIPSAVPANIVVQDSYFHHNGGSGVMLASAIEEDRPTGILIDRVVSTYNASHGVHVQAGTGVALRDVASWGNGLYGVLLSSRTTLPVTSVRVGDVTLKRLLVFDNALRLTSGSHPGIKIEASDVTVRGATVGRCDPSRGRQSQSIQQQCWMSGPAGAQALFHPEDNVISGVSAHGVSAPEVLACPY
>NC_021658.1|WP_020738792.1|9804313_9807955_+|VCBS-repeat-containing-protein
MRWFRFPSMACLGALGGAAAGALVPSDASGGWPPPTSASAADMADAENWPNDPDYGPSATQSGQWSFYSFLPAPSGSARPRPEESAAGMAIDLAWRRTQGDPRVRIAVTGSGILWDDGDLLEKVWLNRGELAPDHMPLHADGTPCAGDGELAGFDCNGDGVLSASDYDDTPGLTPAASAGRPKGDRNGNGRLDAGDLILHFSDGKDDDDNGYVDDIAGWDFFKNDNDPFDDTLNGQGTEGAKIAAAQTNNGLGGAGACPLCRVVPLRVGDSRVADAQDLAKAILYAADLRADVVQCPVTAVDSTAFLQAALDYAHGEGTLVVASVGDEGSRHHSAPAMSNHALPVSAVRYDGPSVQTSTTFLDASPCSSFGGNNLLAVSSAGCASDATAELAGVAGLLYSAALERGVALSPAETQGLLIASADDIDVPESREPGSPYRSSQPGFDQRFGHGRVNANRAVEALRDGRVPPAIDLTSPRWFEVLYKDQVQVPVPIEGTISAKRATAYDYAIEWAPGVQPLESDFRVLQREVNVAPTVVIGAGGPLASLDVRTIDTSHARDADSPHGENDRAITVRAWATARYGGAAGDVRSEARRTYYVASDPTLVDGFPLFVGDSGEGSPKLADLDGDGGREIIYPTAGGELRVLKATPKGPKPLPGFPFRTRHADGLLDPEAPDASPAFYRRARAYDEVAWDKLGREPILGAPAIADLDGDGAQEIAISTWPGTVYVIGADGALRDGWPVRLPEIPSCPLDPGAPASAPCMSPDARIARGAFAAPVLADLDGDGLLDVIQAAFDGNVYAFDAAGGALRGWPVEVHYEGPLAREPARSRLLATPAVADFNGDGLPDLLVGSSERLGDDGDAGAVYVLDARGAAAPSGPVLAGWPVTMPSLSLAPLVAEGIAASGVVGRFGGTLAGVVQGNGAPPLVLPASPGAQDGLLSTPAGALPPPRGGSAAGLDPTFGPLSPAAGARTMLPLLSHPALGDVDQDGTPDVIAAGASEAAALALAGERGAERPAHLLAVWSGRSGAMLPRAPFVLEDHTVGSSQAVVDLNGDGYPEVLTGSSGYFLHAFDGCGREPRGFPKFTGQSIATTPAVGDLDGDGTLEVVVGTRDGWLFAWHTEATTGALVAWESFHHDNRNTGNLETPLDQGGGRSAARPLTVDLCEGPQQAQVMLRLGGGCACAAAGDPRGGAGERAALGAALLGAMALWGRRRRA
>NC_021658.1|WP_020738791.1|9802656_9804186_+|hypothetical-protein
MLGSSPRTGLLLLGALLAALPGCEDADVFIPLPDQSGPAGVLDGTVTYSGPRPCTKDGRVVGAAIVLGFDTRLLPPPEGLGTSAASLDVIPGDELFGGLGAALDLTNDGALRCPAPDDPPVTVSATWRLSPLPAGTYQVRGFYDHDGDFDPIFSIANLPTRGDVAGGAIENAAEVLGGAAPRYREIALAAPIPATGARVSGIAVTLGLPLPLERPIFHVAEVLAPPAGVEEGPGEVVMASDFQLETFSPGDPAGTEASLLRLRLAAGVPDEEIASAAKPPISLPVGGEPAPTLTYARQDVNGDGAIDGDDHVPDSALLPALFPIAVFAKQRADDPLVSQAAPAVLLQGLTIYDDLLTTATLGAEPLDEPRDSALVGVRPAALCMRPTEPERGGVLVISHAKDKEGNDIIAEQDMPEVEEALARQFGRPIEIVYGCLPEGRYALNLIYGTGQAWTVPNEAGVCAPSEAAPSPDVCGARPRLASQDMVLRIGPPDDPAYCAEHPTPALCLP
>NC_021658.1|WP_020738790.1|9799993_9802648_+|TonB-dependent-receptor
MSSPDSCSHGRNGAAPAPAPTHDARPPRPSRPRSGAALARRLLACAVALGATTAARGALADARTEARLHFRAGMDLIAQKQFDEGIRQLQKANEILPHPNVVFNIARAHAEAGHIEQAIAAYREYLASDPADRDQVTRIVEQLEQRLAAQRAAAAPEARQPPAPDPQAPAPAQPAPGDAPAQPPAGQPPAGTAAPTGAAAAPAPAPSSKAAHVDAAGIVGAARTEDVYQETVITASRGAQSPLDSPNSTTIVTRQDIRLSGVTRIPELLRRVAGMDVMQITGGDENVSMRGFNSRLANKLLVLVNGRTVKNDVLGSTFWEALSIDVDQIERIEVVRGPGSALYGADAFAGIVNIITIEPGAGKSGFRAGYGDHQQGYGSVWASAREGDFAYRLSAGYTRYPRWTREVAGDRIDLETSDQSQDLGAENVRIDLRASQRLGPRRELAVGAGYSRSELDIYGIGPFNDYNLEVANTDASVAYRGENVNARTYYSYLDGRSLLNAAYLGHTLYAGRPRQHIVNAELEFAKTLRAPAAVAHDFHIGLGYRLKATDWSYLDGDMPIEHHGSVFLQDSMKLGERVTVVASGRLDYVPYLERLIPSPRGSVIVKPTARQAIRVSGSTAFRSPTSLEAYVDLPIQLALPGLELLSTTRPPVRSDVIIDPEQIITAEASYLNQQSDYFEFEVTAYYNRVSDLIVLAEPQRMTLSQRAQGIGGLNPETGRYTSGFGGFENQCDVYHVVGGELGGRVYPVEGLDIFANYALNLSEQQRPAGCNAPKDERTSRHKVNAGVQVRTPIGVDGEVTFHYQSAQAWAEQVPAGTVIATTVYPLPAYTLLNARLGYRFLDNRAEISATVFNALDGLGEAPLQMHPFGNRIGRRFMGFFRYSL
>NC_021658.1|WP_044989105.1|9797889_9799734_+|serine/threonine-protein-kinase
MPEGRQPEVTGSPRGSRAAAPDPLLGRVINGRFKIVSVIARGGMGKVYRAEQAPLGRICALKVLSPKYEGDHDPEFHRRFFLEASIAAKLSHPNTVTVFDYGQSDDDIYYIAMEYIEGKTLHRVLREDGPFPEARAAHIARQICRSLREAHGLGVVHRDLKPGNVLLVDHEDEHDHVKVLDFGLVKDTQSGEDLTQQGLFMGSPKYMAPEQIAGSGVSARTDIYALGVMMYEMLAGQVPFDKGASVGTLMSHVNDPVPPMQAHNPSLSISQTMEGIVYRCLEKDPAQRFSSMNELLAALKFAAGGISTRDTGETAPMLPGAASHRPSAPSYPSLPAYPRPPSYPSSPSRPSSPSYPSASSYPPTPSYSTTGDIPGLSTPNSSPPTSSPVTLTAPIATDSGLRPPTAPLFVAPSITDSMGTDAMGTDAMGTDAMGARPAPHADGLSSTQPGARPARRLAPWAIAAALAAVVGVAAVMTARSPAAGTSAAAREQGEGSTPAAEAPPAASAPAASAPAARPLQVESTPPGAAVREGNKELCAETPCEIIWRGTAAALASEHELVFEKTGYRSAIVRVSGAEERVRARLDPAPIAAPRAPSKPRANVQKADPYKSNPY
>NC_021658.1|WP_148314135.1|9796530_9797673_+|hypothetical-protein
MEQRRARIAAAALCAAAAFTQGCGDDEDGSAGAASGGGADSAGCLDARSHGALFSLIDPAWCAVAVYTTDEEIGFASVTWGRHGGPMFARSDAGGAAEIVRLTPPEGADGELAAARTTIDAGVPDGAFLGAQAVDLPFFGWTAISWTSAFPETLGELILIEDRAVAARYEVNGFFAAAAVEGRLLYTGLSPLGDAAAGANGLYAADRCGAAGPDARLVPEGDASCAAPDAVAAWGDSSGPVAADPRGNVVAVLPSADGTQEARGFAAEAIARGAGPTEGDVLFSLPGSGTSLAALAPEQGAPGLVVFQPSDPATYEALAPVAVATRDDDGHVRAEGAPAPLVELATAGTLLSLFTDDANRLWIGGPLPDGGFLFAVAVRR
>NC_021658.1|WP_080682436.1|9794440_9796126_-|protein-kinase
MTKTPPPPITAGTVINDRYDIRQSLGKGGMGEVFLAFDRSTQQTVALKVVREESRMPGDDEALRQELLLARSVGHPNVCRVHDLAPSPWGPILVMEQIPGQTLHTHIRKRKAQGGYTADEFRKIASEVCNGLAAIHAQGLVHGDLKPGNVMVSEGRAVILDFGFAQERARASARRPGAPPDGGTPNYMSPERLRNGGASPEDDVYAMALTLWEMWTCRVPEPGYKPRLKTMKQQIMFDVPAGLSIDEVRQIFRGLNEDPSMRPQARHMRFFNPSQLTTSPIQLPRERLDPGPPPGGALKLNFTPGAQSLLVTYATNAPEIVGSLLPLHDTKLALGRRSDQSLCVPEATVSGAHAILKWQTGSWLIEDQGSTNGTYADFNYERKSQVSLLHGGEVQVGECRMKLVTFGPDSPQHRRAKQYLAKRDGLTGLLVREHLMKAIDEDGLFADWAEVPMQVARYELRGPNRQVSERPTILEMLALRKAAQRVIDLTEMLLLSLTPAVAGRTGPLKFVVSIVGPSIDEARHVVEQVVAQVQGMLPETLELGATLVKGEPGRPARTLID
>NC_021658.1|WP_020738787.1|9793786_9794425_-|hypothetical-protein
MNSRPPFPSSPPSQPSPYRYLGRGGGERPVRLQIIIALVAGLIVVAVPLYLWRRPKPESIPSADAATADAGAYAWDAGALADAGAAADEGVTLSPFTTIKCENPGPGTTPPERCDHVTFFEDALARAIRDNVQCAPSGKTSITVSYVLEMDFRRKRTNLYAGKSTTVSRTKTKELIRCVKRAMPTPDWGTIPHQYVKYKINVMATYPANESY
>NC_021658.1|WP_148314946.1|9815389_9816484_+|pectate-lyase
MMPDEAVTLDQTGNPIYAELMNYTSWLSTSGDAAAKLAADKALADNMLTWQMPHGGFYKNKKDIYHAPWNGTDARSGWSGEDDVELGTIDNDATVTELLFLADVYRRSGDARYRDGARKALDFLLTMQYRSGGFPQVYPARAGSSSYSNYVTFNDNAMARVMILLDQIAKVADPLGGDLFTDAQRSSAAAAVAQGIDFILKAQILQAGVKTVWCAQHDPVTYEPRGGRSYELASKSGKESAGVIAFLMSQPQAADVKEAVQAAIAWYKSSGVKVEDTAYVKRPSGSTDDSYNPIQAKAGSTMWYRFYDLDQDVGFFSGRLPTDDPPGVGKKYDIMEIEPERRYGYEWGGSYGTKLFAYSDAVGY
>NC_021658.1|WP_049949893.1|9816581_9818207_+|family-43-glycosylhydrolase
MGLSACCGDDLEAPPSEPAANESEAPTWARGIEGQRKADLGDGYYLNPIMPGDHPDPTIIKEGADYYMTFSSFDAIPGLVIWHSQDLVNWEPVGPAVTTPVDSIWAPELTKHGDTFYLYFVTNKTDPVTGAKTKKFYVITADDIRGPWTPPLEIVVKREDGSNGASSDPGHIVGEDGKRYIFMTGGARVQLKDDGLSVADGEAGIPKIVYNGWEYPEEWDVESFSQEGPKMLKRGEYYYMVLAEGGTAGPPTGHMVVSARSRSIHGPWENSPYNPIVRTQSAEEKWWSRGHATLIEGPDQKWYMVYHGYENSFMTLGRQTLLEPIEWTDDGWFTSAGHDVGKPIPKPAGGKAVPHGIAFSDSFTPERFDLIWSFYQAGADEKSRLTFDDGALTLAAKGSSPKDTTPLIMNAGDLAYQVEVQMDWDADAQAGLMLFYSQRLYAGLAFNSTGTVMHRYGLERDGKKIADIQGNRAFMRLVNRRNIVTIYTSPDNETWTKYGVQMEVSGYHQNVGYDFQALRPALYASGEGSVRFSNFKYTALP
>NC_021658.1|WP_187345692.1|9819082_9819676_+|hypothetical-protein
MPPRSPPPTRARARPTGGSVERAALFRIGLGGMSDLGTMQRMSGAIEPWAGVVVGPARIEAGASFWPGRRAESAARPGTGGTIDLVAGSLTACALLPPLERAVRPDVEVDVPCAGVELGRMHAEGYGVSDPGEGSGVWVALRSGAAASWVVAPWMRLRLRLEAVVPLERPRFVLEGVGEVHEPSVAARAALGLELAL
>NC_021658.1|WP_080682776.1|9819749_9820346_+|sigma-70-family-RNA-polymerase-sigma-factor
MSAESAGAEVAPPAEAADCAVALEFDAIYERYFDFVWRNVRRLGVPDCHADDAVQEVFLVVHRKLPAFEPRPTLRAWLSGIVARVAREHRRAYARKSPLARSLAPPLDPDEVESGAAGGDEALAQAQATRLLHALLEGLDDHKRAVFVLAELEQMTAPEIAEATGANLNTVYARLRAARKEFEQGVARLRARDGWRSR
>NC_021658.1|WP_044986411.1|9820395_9821175_+|hypothetical-protein
MSQLGPLSRSIIEAARNGDRSTAADRARVRAKLRKSLAVGTALTAGGAAKAGFAMVSAKAALPWGIVALLAPAAVVTALHTAQGEPRAVPRASAASAAVLERARAAAAAQPAARDDRAPAERPREPAPPIAPAEGKELDPRQAARTRATTPRRAPRPGASGGPEAPPGVPAEDPLIAETRRLREVHEALRRGAPERALSLLDAADAGGQELREERAAARVVALCALGRTAEGRAAMLELLRKSPGSPYSGRVRAACEEK
>NC_021658.1|WP_020738803.1|9821241_9822135_+|hypothetical-protein
MKIQMLIGAAGLTIVAAMFSCTPEIIAIGQDKQQVACSTDAECGPGETCGAGMCQASCVADADCPSGLSCVNGACLDGAPSGLCTTDADCLAGLSCVNGACLDGAPSGLCAVDADCAVGFYCMSGACVHGSVFCKCTTDADCPGDQFCMRGDTCGFGAGLCATDADCPVHGQACSDGVCEGPGQAHCASDAECGEDHVCMGEVCKSTLPAKGTEHCMPLVDPECVADADCPGALLCARNGTCIADGPAPCTIDADCPLRGQICSGDTCEGPWGQLCASDADCPENHVCISEECKSTR
>NC_021658.1|WP_080682437.1|9822458_9824240_+|trypsin-like-peptidase-domain-containing-protein
MRISARVSSALTAASAMMMGCVAAPDLDEQLVGEVAQPSICGTTADFQHVEQYDGTLGVTAGFVGARESPVGQIQWKSDLASRYANPGNVSGTRTCSGTLIAHNLFLTAGHCFDPDGNGWTWPRTASSTPISASQGAVEMRVNFDYQEDPSGNLRTAESFDIVSLREHRLGGLDYAVVQLARSAAASYGFTVVSTTDAAVNDMLAVIGHPSGEPKQVDAGPATSFSGDYIQYGSLDTLGGNSGSGVLHAASGKIVGVHTNGGCTSIGGANSGVRITSILEESPILRDVTQRLVVFAKGSDNAIWHKFYDGGWSSWTSLGGSLTSSPSATLTREGRLTVFAKGSDNAIWHKYYDGGWSGWTSLGGPLASAPAATVTREGRLTVFARGTDNAIWHKYYDGGWSGWTSLGGPLASAPAATVTREGRLTVFARGTDNAIWHKYYDGGWSSWISLGGATTHDPAAVVTAEGRLVVFARSSSGELVHRYYDGGWSSWISLGGAIASGPSAVVTAEGRLTVFARGADNAIWHKYYDGGWSGWISLGGAMVDQPGSAVTPEGRLVVFARGTDNAIWHKYYDGGWSSWISLGGALTSSPAGI
>NC_021658.1|WP_187345693.1|9824294_9825797_-|hypothetical-protein
MRAPSTRVATTNHSSGIGSPPWAHRCASIALSIAVLVSAVACEPSGGGGGAGGEGGGAGGEGGGAGGEGGSGAGGEGGSGGAGGEGSGAGGEGGSGGAGGEGGAGGSSTAPTLAWARVYGGPGVDQGHVIASDAEGNFYVTGSFEGTVDFGAGPLTSGGQDDIFLLKLGPSGELLWSKRFGNDHDERGTRLATDGNGNIFLAGVYNANIVTPGESDNVDFGGGPLPGDDPGEYGFLVKLDRDGNHVWSWDSFDFRVTSLAVDATGHVYTVTSSFQYGAYLARKDGATGGQLWGTWIVNGGGWPFTTSLALDSAGNVVFASGTESGPGVCPCQQRFGVGKLTPAGGLLWRRSFSDGEPSPGAATYGAMAHVVAVNTADEIFVAGHSLGNVDFGGGVLPAGDVLVKLDPSGEHVFSRPSHRIFFMVGDRDGNILVDDGHIVNLDPNGTKLWTLPFWVPLSRVSVSPLGTIAATGSTTTALDFGDGPLPFAGALDISVVALNP
>NC_021658.1|WP_148314947.1|9826034_9827396_-|tyrosine-type-recombinase/integrase
MPTCRTEHDANARLEVLADLSRHLLAAGQIVLGLPLLEQAAAREGSALRDVRLAINHLCRGEARARASGETTFAEFAERVLSGKLAEQYPDHVKAIRTADKYEQRLGHVLDVLGPVPLVRFTLDHADHAMSRLPVHLEPGSRRNIAIVIHRLLALAAYLARIIAHNPLPRGWIPKIENNKAKGYLYPDEDQRLMRSQLVPLCFRIYYGFLTREGMRADEAGTLEWSDVDLDRGAVVLDENKTDDPRAWALSPDVVRALRAYRELWPDNRRVFVGPKCDPLPGCHGAEPFREHLQRAGVDRPDLFETTESRLNIRLHDTRATFITIKLANGRTETWISDRTGHKSSGQIHHYKRAARKIAELGLGDFAPLDEAIPELRGKGGSVGGGQPASAGAGMGSASAEASASGAPPGQTAPPDDVPAPRHGGRWRLHRRFVGPALGHAGRGLGHAAVGTN
>NC_021658.1|WP_020738807.1|9827782_9828187_-|hypothetical-protein
MIGQPATATATATLAIPLDGLTITAPQPEMLSQKNVESVTGIPARVFLDTIRAPGFPLLITKLGKLRVVQRESFVAYLRALASEPASRRTAEADENTRVAAVLASAGLEPVPQRPTGRASARHADARRARLALK

Crispr_ID: NC_021658_43

• CRISPR_ID: NC_021658_43
• CRISPR_location: 9915030-9915102
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_43

Consensus_repeat	Method
CGCGCTCGTCCAGCGCGCGCCGC	CRISPRCasFinder

spacers of NC_021658_43

>43.1|9915053|27|NC_021658|CRISPRCasFinder
GCCAGTGTGACGGCGCGGCGAGCTCGA

CRISPR arrays and Neighbor proteins around NC_021658_43

CRISPR arrays

The CRISPR arrays of NC_021658_43

>merge|NC_021658|43|9915030-9915102|CRISPRCasFinder
CGCGCTCGTCCAGCGCGCGCCGCGCCAGTGTGACGGCGCGGCGAGCTCGACGCGCTCGTCCAGCGCGCGCTCG

>NC_021658|43|38|9915030-9915102|CRISPRCasFinder
CGCGCTCGTCCAGCGCGCGCCGC	GCCAGTGTGACGGCGCGGCGAGCTCGA
CGCGCTCGTCCAGCGCGCGCTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020738863.1|9909752_9911507_-|AMP-binding-protein	unknown	unknown	gnl|CDD|341286
NC_021658.1|WP_148314148.1|9918106_9919063_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|237124
NC_021658.1|WP_020738861.1|9907653_9908499_-|kinase/pyrophosphorylase	unknown	unknown	gnl|CDD|377080
NC_021658.1|WP_020738867.1|9916387_9916693_+|PilZ-domain-containing-protein	unknown	unknown	gnl|CDD|377796
NC_021658.1|WP_044986420.1|9919897_9920749_+|purine-nucleoside-phosphorylase	unknown	unknown	gnl|CDD|350160
NC_021658.1|WP_049949729.1|9908599_9909700_-|molecular-chaperone-DnaJ	unknown	unknown	gnl|CDD|236757
NC_021658.1|WP_044989121.1|9914448_9915012_+|hemerythrin-domain-containing-protein	unknown	unknown	gnl|CDD|213983
NC_021658.1|WP_020738857.1|9905304_9906165_+|ATP-dependent-sacrificial-sulfur-transferase-LarE	unknown	unknown	gnl|CDD|238948
NC_021658.1|WP_044989123.1|9924638_9925808_-|ATP-dependent-6-phosphofructokinase	unknown	unknown	gnl|CDD|274155
NC_021658.1|WP_020738866.1|9915153_9916314_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044986417.1|9912039_9914283_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738858.1|9906313_9906619_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044986419.1|9919409_9919853_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044986422.1|9927369_9928854_-|Do-family-serine-endopeptidase	unknown	unknown	gnl|CDD|273938
NC_021658.1|WP_148314146.1|9907202_9907646_+|hypothetical-protein	unknown	unknown	gnl|CDD|185616
NC_021658.1|WP_044986421.1|9921246_9924435_-|response-regulator	unknown	unknown	gnl|CDD|274008
NC_021658.1|WP_020738864.1|9911555_9911960_+|TIGR02266-family-protein	unknown	unknown	gnl|CDD|274060
NC_021658.1|WP_049949895.1|9920745_9921207_+|cytidine-deaminase	unknown	unknown	gnl|CDD|273572
NC_021658.1|WP_148314147.1|9916745_9918110_-|FecR-domain-containing-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_020738859.1|9906584_9907196_-|hypothetical-protein	unknown	unknown	gnl|CDD|371647

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020738863.1|9909752_9911507_-|AMP-binding-protein	gnl|CDD|341286	cd17631, FACL_FadD13-like, fatty acyl-CoA synthetase, including FadD13. This family contains fatty acyl-CoA synthetases, including Mycobacterium tuberculosis acid-induced operon MymA encoding the fatty acyl-CoA synthetase FadD13 which is essential for virulence and intracellular growth of the pathogen. The fatty acyl-CoA synthetase activates lipids before entering into the metabolic pathways and is also involved in transmembrane lipid transport. However, unlike soluble fatty acyl-CoA synthetases, but like the mammalian integral-membrane very-long-chain acyl-CoA synthetases, FadD13 accepts lipid substrates up to the maximum length of C26, and this is facilitated by an extensive hydrophobic tunnel from the active site to a positively charged patch. Also included is feruloyl-CoA synthetase (Fcs) in Rhodococcus strains where it is involved in biotechnological vanillin production from eugenol and ferulic acid via a non-beta-oxidative pathway.	1.34188e-139
NC_021658.1|WP_020738864.1|9911555_9911960_+|TIGR02266-family-protein	gnl|CDD|274060	TIGR02266, gmx_TIGR02266, Myxococcus xanthus paralogous domain TIGR02266. This domain is related to Type IV pilus assembly protein PilZ (pfam07238). It is found in at least 12 copies in Myxococcus xanthus DK 1622.	6.99909e-22
NC_021658.1|WP_020738861.1|9907653_9908499_-|kinase/pyrophosphorylase	gnl|CDD|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	1.27433e-119
NC_021658.1|WP_148314147.1|9916745_9918110_-|FecR-domain-containing-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	3.79265e-08
NC_021658.1|WP_044986420.1|9919897_9920749_+|purine-nucleoside-phosphorylase	gnl|CDD|350160	cd09009, PNP-EcPNPII_like, purine nucleoside phosphorylases similar to human PNP and Escherichia coli PNP-II (XapA). Human PNP catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. Patients with PNP deficiency typically present with severe immunodeficiency, neurological dysfunction, and autoimmunity. Escherichia coli PNPII, product of the xapA/pndA gene, catalyzes the phosphorolysis of xanthosine, inosine and guanosine with equal efficiency and has been referred to as xanthosine phosphorylase and inosine-guanosine phosphorylase. E. coli PNPII is also capable of converting nicotinamide to nicotinamide riboside, and may be involved in the NAD+ salvage pathway. It is one of two purine nucleoside phosphorylases found in E. coli, which also contains PNPI, which displays a different substrate specificity and belongs to a different subgroup of the nucleoside phosphorylase-I (NP-I) family than PNPII. NP-I family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	2.76695e-151
NC_021658.1|WP_049949729.1|9908599_9909700_-|molecular-chaperone-DnaJ	gnl|CDD|236757	PRK10767, PRK10767, chaperone protein DnaJ; Provisional.	5.65355e-149
NC_021658.1|WP_044989121.1|9914448_9915012_+|hemerythrin-domain-containing-protein	gnl|CDD|213983	cd12108, Hr-like, Hemerythrin-like domain. Hemerythrin (Hr) like domains have the same four alpha helix bundle and a similar, but slightly different active site structure than hemerythrin. They are non-heme diiron binding proteins mainly found in bacteria and eukaryotes. Like Hr, they may be involved in oxygen transport or like human FBXL5 (F-box and leucine-rich repeat protein 5), a member of this group, play a role in cellular iron homeostasis.	4.16842e-12
NC_021658.1|WP_020738857.1|9905304_9906165_+|ATP-dependent-sacrificial-sulfur-transferase-LarE	gnl|CDD|238948	cd01990, Alpha_ANH_like_I, This is a subfamily of Adenine nucleotide alpha hydrolases superfamily. Adenine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily of proteins probably binds ATP. This domain is about 200 amino acids long with a strongly conserved motif SGGKD at the N terminus.	7.85261e-89
NC_021658.1|WP_044989123.1|9924638_9925808_-|ATP-dependent-6-phosphofructokinase	gnl|CDD|274155	TIGR02483, ATP-dependent_6-phosphofructokinase_1, phosphofructokinase. Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis].	7.94818e-145
NC_021658.1|WP_020738867.1|9916387_9916693_+|PilZ-domain-containing-protein	gnl|CDD|377796	pfam07238, PilZ, PilZ domain. PilZ is a c-di-GMP binding domain which is found C terminal to pfam07317. Proteins which contain PilZ are known to interact with the flagellar switch-complex proteins FliG and FliM. This interaction results in a reduction of torque generation and induces CCW motor bias. This domain forms a beta barrel structure.	8.32398e-12
NC_021658.1|WP_044986422.1|9927369_9928854_-|Do-family-serine-endopeptidase	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	7.64669e-146
NC_021658.1|WP_148314146.1|9907202_9907646_+|hypothetical-protein	gnl|CDD|185616	PTZ00436, PTZ00436, 60S ribosomal protein L19-like protein; Provisional.	0.00158611
NC_021658.1|WP_044986421.1|9921246_9924435_-|response-regulator	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	3.24887e-22
NC_021658.1|WP_148314148.1|9918106_9919063_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|237124	PRK12518, PRK12518, RNA polymerase sigma factor; Provisional.	1.4358e-35
NC_021658.1|WP_049949895.1|9920745_9921207_+|cytidine-deaminase	gnl|CDD|273572	TIGR01354, Cytidine_deaminase, cytidine deaminase, homotetrameric. This small, homotetrameric zinc metalloprotein is found in humans and most bacteria. A related, homodimeric form with a much larger subunit is found in E. coli and in Arabidopsis. Both types may act on deoxycytidine as well as cytidine. [Purines, pyrimidines, nucleosides, and nucleotides, Salvage of nucleosides and nucleotides].	9.03198e-46
NC_021658.1|WP_020738859.1|9906584_9907196_-|hypothetical-protein	gnl|CDD|371647	pfam11645, PDDEXK_5, PD-(D/E)XK endonuclease. This family of endonucleases includes a group I intron-encoded endonuclease. This family belongs to the PD-(D/E)XK superfamily.	3.82488e-05

Protein sequences

>NC_021658.1|WP_044989121.1|9914448_9915012_+|hemerythrin-domain-containing-protein
MSDDRNDPLEKLASAHRSLEENLNDLARAARALGDPRGRAAALEGLSSVVAYFERSMSRHHEDEERSLFPRLAVLEAIAPTLERLRQEHKAHQRAINELRAAIERDGGPEALEKLPQLIEDLRAAYHRHVTCEEQEVFPAARRFLQASAMHGIMNEMETRRGRGGHGNPAKGISGRPYRPGGMRRGP
>NC_021658.1|WP_044986417.1|9912039_9914283_+|hypothetical-protein
MSLPTLPPRRRLARGLAALALALSPLACAASGTPGAKGPPGAEGRAAPVEVRDADFSASLYTIVRDGKQSSQRTGLLIGVVRRQLAHAAARFHAGQPSRGVDSVRGALYLVRPGEGHAEMIDAVGERALDGAIERLSPRGDEGRVRALMELRAAALPAGSRARAEVDEHLAALDRWMKDTRTGGPLEQLGMEQRASVSRALLDSRPEAIQRAAAATAAWIDRAIEFNIEYRQGGKRPEREEAVEAARALESGGASMAALFLRYGDAQGALEQIDRTSARRVIPPGLYDRLKAAASDGDAVSWQALAAAFAHHDTQERDAETGMLQDLLDGAIWGTALEAYRRDPQSYDSASLLSQVMIRLGMSEATPLLLAGALGDRPSAGALGSALGLVLGALSEEASNDDFEAARRTYNAAGPLLVLADRAARGGAAVDPSGARVRSLMASLELRAGNLAGALPLLRAATAAEPTVNGLTLLAMAERQSGELQAALEDVRRALGAPDARTAPLEVIQAHLLAFELHREAGTQDRAKESLDAALAAALDARQRARDPGAKARTERLLGRILDGYGDEKGATRAYERAFALVAAEPPQLGATMLDAVGRALVERDLPAARRALKRGLEANLDEEDLVYGGLWVLLLERSLGVATDGTAGRALDSAVNRASWTGKLAAWANGKISDADLGKLAQNAAQRVEAQFYTAMAKKAAGDAGADERLRAVSKSPVIDLLEVHLAREMLAPELRLELPRNASLP
>NC_021658.1|WP_020738864.1|9911555_9911960_+|TIGR02266-family-protein
MTEADRRSAQRAAIELSVEYKRLNTFFADYTRNISKGGTFIRTERPLAIGTEFVFALSIRNLAEPLRLRGRVKWIVMPAEATETAPAGMGIEFQYASEAERGATEAVVEQLMMNELGETLASKLLGRKLGDGAR
>NC_021658.1|WP_020738863.1|9909752_9911507_-|AMP-binding-protein
MELGHVRAALASGRRRASALKDGALVAGRAVTQTGLLAALRWPGLKVLARELAKGKANPSLLFRFYAENSPHRIAVIDPRSLGPRSLGRRAAEGEAAAPAEDRVHSFFALNEAIERLGHALDRRGVGPGATVLLALKNRPEFVMCQIALARVGASVVTASWRSTPAELSYLAGHSGARLLVFDADIAGVIREAAPRLEGIPPEAMIAVGEGAPGFSRFDELLAEPGAAPDRSERAAVVMYTSGTTGKPKGAVRGFGGGVVMSALGAIGATPMRAGDVHLAVCPLYHLTAFGFVNLSLVLGATIVILPEFHPELFLEAIQRYRVTTTAVVPTMLHRVLELGEARLRAYDTSSLTAIFAGGAPLPPALAAEVMGVFGDKLFNFYGATETGIVTIAGPEDLRASPGTIGRPVAGSALLLVGDDGRPCRDGEVGELYVRSPLLVSGYHRDPGATRASTLDGYFSVGDLARRDARGCYHIEGRKRDLIISGGVNVYPAEVEAVLHDHPAVAEAAVVGAPDRAWGERVRAFVALRPGASASEDDIKAHCRAALASPKVPREIVFVDALPRNPTGKVMKRELAGPERKPAG
>NC_021658.1|WP_049949729.1|9908599_9909700_-|molecular-chaperone-DnaJ
MRDPYEVLGVERSSTQDEIKSAFRRLAAQHHPDKNPGDQGAHVRFKELNAAYQILSDPQKRAAFDRFGPAAVGAAAGSGFQGVPFDMQDLNLDAIFGDLLGALGIKVGDRGTLQKEVRISFEEAAFGCAKQITYDRVEPCGDCAGSGSAPGSSTERCAACAGRGRVRMQQGMFPIAIERPCGKCRGTGRIVIDPCKTCRGAGLAAKQKTIEVTIPAGVENGATRLVERGGNAVRPDRGPGDLELTIRVAPHELFRRIGDDVVCAVPISFARAALGGELEIPTLDGKGRLRIPPGTQPGSVLRIKGKGIPRRVVGGRGDQLVEVSVEVPTQLTASQKELIAQLAKELGENVQPQQVTFMDKLKGLFG
>NC_021658.1|WP_020738861.1|9907653_9908499_-|kinase/pyrophosphorylase
MDKPKFIDVLSDSTGETAEKAVRAALLQYPDAGVQIRLHTRVRTPEVARPVLERAAREGALVVFTVVSPELREFVHASTAQLNIEAIDLIGSLIVRLGTFLDREPINLPSAMLPLSEEYFRRIEAVEFAVKSDDGKEPRNFKRADIVLVGVSRTSKTPLSTLLAQRGLKVANLPLVLGVAPPPELMDAPQDRVIGLTIGIDQLCEIRQARLRQLGMPAETNYAVREHVRQELDYANRLFAAHPEWPVVDVTGRAIEETAVIILEHLKERDERAKAARSSLM
>NC_021658.1|WP_148314146.1|9907202_9907646_+|hypothetical-protein
MLDLGMSRHHPWHESLDTHPAHLDTHPAHLDTHPAHLDTHPAHLDTHPAHLDTHPAHLDTHPAHLDTHPAHLDTHPAHLDTHPAHLDTHPAHLDTHPAHLDTHPAHLDTPQPTRTRRSPPGHAAAHPDTPLPWLRAVRQRRASPLAR
>NC_021658.1|WP_020738859.1|9906584_9907196_-|hypothetical-protein
MVSKRTHFGRAGEYYAMSELLLRGWNVAVPVVDVGDDAFVIDDRDKTTRRVQVKTAKAEPVEGHTESSGARRVRATFNLSRQQLRTQQPIELFYMLLVRLPASWKFLVIPRRDLFQMREAYVAVARTSPGRRPRSDGDATTDTLIFAVDVEPETNVAHGWGGALDRYLDRWPDELWVVEGGPGSVGSGSAAEPMPPSAGDPSR
>NC_021658.1|WP_020738858.1|9906313_9906619_+|hypothetical-protein
MSEATAEPIVIYRSINRDGATFALEPRSLDRLRATFGSAVRARDRIFIAHETRADYEEVQGSIAPQIVVLLTGLSEDRLRPLGGVVFRDPVSEKDLPRTAA
>NC_021658.1|WP_020738857.1|9905304_9906165_+|ATP-dependent-sacrificial-sulfur-transferase-LarE
MSAPSLTPEGSPIDTKLARLRVRIRELGSVLVCYSGGVDSAFVLAVAHQELGPKAVGMTAVSPSLAPAEKEEAAAIARLIGADHRLVESSEIDDPRYVANNPDRCFHCKSELYRIAARKRAEWGLAAILNGTNTDDLGDYRPGLEAAREAGVVSPLVELGFSKADVRAGAARVGLPIWDKPAAACLSSRIPYGTSVTRERLAQIGGFEAALRGLGFRQVRVRYHDDLARIELDAGELARAAEPAVRAEVVAAGKRHGFRYVTLDLGGYRTGSHNEVLVGRALKIVS
>NC_021658.1|WP_020738866.1|9915153_9916314_-|hypothetical-protein
MSRAESASVKRREPRSAPSTRGPAGGLPHLLPVPARGVEARAPERRGLRRHLEGWEPGLVAVFIAGSAAILAVPRAVEPAEVPLPLADARALTRVRDADVARAREAEQLGLDAEVRALGSAIRAFGIVDADADHTEAELLAARKRVLEAAGPALAQGDEAVLRLRAYQMSSFVREVRRFEATGEASDELRELGGDFPGLLRRNAWLSAGGAGPRGGGGEARRVAMDGAALGALFKKRWDAIVGLRRAPFGVALDEERALYKFLLSHPLSGRSAQELAAPPAAETAARLEPQAGEPGPRSPAAALRAAEAQRAEEHYRLKKIDELAALDPAYPRHLARGIALYRLGKFVQSADAFRSHLDHHPDGAHTLRAQNYLRAALERASEERF
>NC_021658.1|WP_020738867.1|9916387_9916693_+|PilZ-domain-containing-protein
MRDHRKHPRKPIELSIAFRIGDGPRIDAICRDISLGGMFIETTSPAPFGASIEVLLSLEGLKQAAAIPSVVRWTTPEGMGVQFGVMGARETYALTQLLGSL
>NC_021658.1|WP_148314147.1|9916745_9918110_-|FecR-domain-containing-protein
MSGAKQYERAREHMERLLRAEEPPEPRWDEIERELFARIERPAPVRRAAPPRRSPLGRALAFAAAAAAIAFAVLAAGRSAPPVVATSTPPRARDLADVPRAAGAADDLDFRALRPGDAVETAAHAISFADVGSVRWTLLPNSRAVVRAVGAAGVGHVIALERGAVRADVVTRAPEEGLVEAFAVEVDGTRVAVHGTLFTVTRLADRVEVDVEHGTVAVGPAAYRGATTAHLLVGPSRGTFSLDGGREARLLQRPAPEGNAAPEGNAAPEGSAAPEDGAPAASPTEPARPPAPPRPTAGATAGVRTASGAAAARVVVAQVEETAAASATPAAPAVAEPPSTVADPPPAPAIESAPAAAAPVADAQATPPPPALTPASVQSQLSSCFAREAAGGPSLVRKSIASTLRISVRPDGSVAAMRFDPPLRPALQACAQSLYQGRFAGGPMHLAIPFIIED
>NC_021658.1|WP_148314148.1|9918106_9919063_-|sigma-70-family-RNA-polymerase-sigma-factor
MRGFVHTVEVETGALWAHLSRSFLFPLGWGAPAGRADELPARAAEGARVALDVTSAGDDLSRRPELVASPSSSMSAEGADRLPPVTEPDDVGEWIRRFQSGDPTAFAEIFRRYRRDVARLVFRMLGPSADAEDVIQEVFIQVHRSLGDFRGQSKFTTWLHRVTVNAVLMARRAARSRPVFAGEPSVELEIDRGMLPDEDAARARRIDAFRRVLERLPEKKRVVYVLHELEGIAPTEIAEIVGAPVLTVRTRLFYARREIEAMMRAEPALAQLAAELAEGGADKADGAGPEAARARVSVGGAAVRYPAADGSTVDAEDM
>NC_021658.1|WP_044986419.1|9919409_9919853_-|hypothetical-protein
MHSDIARDRVAALSGQVTTMGTKIEDFLKEKKIDPRRILAASVKIERLQPEDRAIRLTKRLARGSEDAAKKKEAAGAKKPRSGRPVTDRTLSAALQGKPISGPAKTRLLRAVNRILEQKKQEKVALSALFDLPKKGGAAAEGAEAAG
>NC_021658.1|WP_044986420.1|9919897_9920749_+|purine-nucleoside-phosphorylase
MTLLAELDEAARVIRQRISALPSVGVVLGSGLGGWGDELSGLVKVPYAEIPGMPRPAVEGHAGFLCAGRVGDVPVACLQGRAHLYEGHPPAKAVFGVRMLARLGCRAVLLTNAAGGINPGFGAGDLMLLTDHLNLMGTNPLVGPNDDALGKRFPDMTYAHDPRLLDLARAAASDAGVPLREGVYAGLLGPTYETPAEIRMLRTLGADAVGMSTVPEIIALRHMGVPAAAISCITNLAAGLTQRELDHKEVEETARRARARFTALLSAWVRRVGAGAAAGSAAS
>NC_021658.1|WP_049949895.1|9920745_9921207_+|cytidine-deaminase
MSRAPQDAGEAPAAAEAAPAIDWDALDRAALAVRERAHAPYSGYWVGAAILVRSGRVFAGCNVENASYGLAICAERSAIVQMVAAGERDPIALTVATSGPVLGSPCGMCRQTLAEFAADLPIRLIAADGGAPPRLTSLAALLPEAFGAAALSR
>NC_021658.1|WP_044986421.1|9921246_9924435_-|response-regulator
MTKVLVFESDPAFAGELRTELGRLGCTVQVVDDGNVGLQAAAADRPDLILLSIELPRMNGFSVCNKLKKDVQLKDVPLVIMSSESSEETFEQHRKLRTRAEDYIHKPIAFGELLEHIRNYVPLDGDEAEADPIMIDEAEVLEADIDEDSGDPTIITAAVSSNGTPASVAPPPPAAPRPPSAAPPPPAAAAQDRARAPGPTKPPQAPAVRSNSGKSDEDIEEFIGGAFTRLIRDEEEERTDVRPSVAPSTRTPSAAPSTRTPASTSTPLPASAPPPVSSSPVAAYRAPVSERGGAYRAPVSERGRLTPAPPAPRADADAGEIERLRAELDRSKDEIVRLTKEVASARATSLRLEGELSSANDGSQEAARLRRELEELRAKAATGGSPSRPGGVSSREFLDLREALNKKDKEILALRDQMSRKDKELLELRDQALSLEREKADQVDKILELERASEDLDAQVASLRADKELAAKRADDFRARAEKLQAQIAGRDAELSAARQALMDAEAAHTEGLRSAADERAQAIAAVEASARREIEETAQAERERFEQAAAAHRAEVERLSAEHAARVEQQAAEHRAAADRLAGEHAAAIDKLAGEHAAALERAKAEHAAVADGLRAEHAAATDGLRAEHAAAVDRLRVEHAAAMDGVRAEHATALDRQRAEHDAAVATSQREHEAAVEALRREHADETERRDRERAAALDAARAEHAAAVERLSAEHAAAVERTSAEHAAALQGARAEQVAALERQQGEHATAVEALRGEHAAALEALRTEHATAVEALRGEHATALETLRREHADDRERRDREHAAALEALRTEHAAAVEGQANEHARALEAAREDFAARLAARERELVDEREQAVRAAEQAHAARVADLEARAAERQAQIEAAHAQALADLRGTHEAEIAEREAAWAAQKHELDEIARGLSTELGQARNQVAHLEGRAHDLEQQLEQRAGELSARTGERDRLQGELADRARDVEALQGRLAEAEQRESELGAQLSHRTEERDTLRTQGEQLAEQLAVERARLQKARSKWGEDRASLERAREALASALSQIEQNEVLSVE
>NC_021658.1|WP_044989123.1|9924638_9925808_-|ATP-dependent-6-phosphofructokinase
MSIASPRMARNAGRLMAARKIAISTGGGDAPGLNAVIRAATLGALERGWEVWGIRQGYRGLLEDSPDGLIRLDRERVRGIAHLGGTILGTANRGDPFHYPTPGEHGLVPRDRSEDLVKRFRALGFDALISVGGDGSMRIAHELLQRGLPLVIGVPKTIDNDVCCTDLTFGFDTAVSIATEALDRLHTTTEAHERIMVVEVMGRHAGWIALNAGIAGGADVILMPEIPFRYEPIAEKIRLRESRGRRFSIVVAAEGAHSQGGELIIKDAGDAFRRTAVLGGVAERVAKELAARTGKEARSMVLGHLQRGGGPTTADRLLALRFGAAAARCLVEDCGSGMVALRANRIELVPLDEVAGKTKTVPLDSDTVVTAREMGLCFGDEPPGHFAAT
>NC_021658.1|WP_044986422.1|9927369_9928854_-|Do-family-serine-endopeptidase
MIQAVSYRSRASALALLSMAALAFGGCGQQAHATPPSTQAAAAAPSAAPPPVSTVTLPPAPVPATFDVAALSERIRPMVVNITTTHESRGPEGLDPFDFFFGPHGGGRLNPRGGQRPPQTALGTGFIIDPSGYVVTNEHVIREASGVRVRLADEREFEAEVVGRDPKLDLALLRLKGASGLPVAPLGDSEQLRVGEHVLAVGNPFGLGHTVTLGIVSAKARAIGAGPYDDFIQTDASINPGNSGGPLFNWRGEVVGINTAIRAGANGIGFAIPVDALKDVLPQLREKGFVERGKLGLSFQPVTRELAAALQLDAPKGALVAEVEPGGAAARAGIKPGDVIVDVNGTPILHAEELRRNVARNAPGSEIEVTVVRGQKRQELRAKLDVLQDEEGDAQGRARPSQGARPERQQSAEKLGIHISDVAGGGVRVDGFAQGVDTQELQVGDVILEVNGAPIRDVAGLRAAIGKTKEGSTALLKVRRGKVVQFAAVPIPAR

Crispr_ID: NC_021658_44

• CRISPR_ID: NC_021658_44
• CRISPR_location: 9972876-9972953
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_44

Consensus_repeat	Method
CCCGAGCAGCGCCTCGCCGGGCTC	CRISPRCasFinder

spacers of NC_021658_44

>44.1|9972900|30|NC_021658|CRISPRCasFinder
GCCCCGGAGCAGGTGCTGCAGGCGTACGCG

CRISPR arrays and Neighbor proteins around NC_021658_44

CRISPR arrays

The CRISPR arrays of NC_021658_44

>merge|NC_021658|44|9972876-9972953|CRISPRCasFinder
CCCGAGCAGCGCCTCGCCGGGCTCGCCCCGGAGCAGGTGCTGCAGGCGTACGCGCCCGAGCAGCGCCTCGCGGGGCTC

>NC_021658|44|39|9972876-9972953|CRISPRCasFinder
CCCGAGCAGCGCCTCGCCGGGCTC	GCCCCGGAGCAGGTGCTGCAGGCGTACGCG
CCCGAGCAGCGCCTCGCGGGGCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_044986430.1|9978222_9980556_-|xanthine-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|376913
NC_021658.1|WP_020738922.1|9987341_9988211_+|hypothetical-protein	unknown	unknown	gnl|CDD|131694
NC_021658.1|WP_044989129.1|9966301_9966928_-|JAB-domain-containing-protein	unknown	unknown	gnl|CDD|377189
NC_021658.1|WP_148314150.1|9965167_9966226_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738916.1|9976817_9977747_-|FAD-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224238
NC_021658.1|WP_080682778.1|9968358_9968694_-|phage-integrase-N-terminal-SAM-like-domain-containing-protein	unknown	unknown	gnl|CDD|131303
NC_021658.1|WP_020738905.1|9964753_9965083_-|hypothetical-protein	unknown	unknown	gnl|CDD|181700
NC_021658.1|WP_044986428.1|9974455_9975322_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080682449.1|9973439_9974303_+|reverse-transcriptase-like-protein	unknown	unknown	gnl|CDD|260008
NC_021658.1|WP_148314151.1|9969131_9970205_+|hypothetical-protein	unknown	unknown	gnl|CDD|376162
NC_021658.1|WP_020738919.1|9980670_9981309_-|nucleotidyltransferase-family-protein	unknown	unknown	gnl|CDD|378957
NC_021658.1|WP_020738908.1|9966924_9967575_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NC_021658.1|WP_148314152.1|9971253_9971862_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044989132.1|9977743_9978226_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|224991
NC_021658.1|WP_020738920.1|9981305_9982268_-|XdhC-family-protein	unknown	unknown	gnl|CDD|224886
NC_021658.1|WP_020738909.1|9967739_9968021_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NC_021658.1|WP_020738911.1|9970495_9971155_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314951.1|9963843_9964212_+|TerB-family-tellurite-resistance-protein	unknown	unknown	gnl|CDD|143583
NC_021658.1|WP_020738921.1|9982518_9987345_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226459
NC_021658.1|WP_020738915.1|9976613_9976817_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020738922.1|9987341_9988211_+|hypothetical-protein	gnl|CDD|131694	TIGR02646, Hypothetical_protein_SMc04429, TIGR02646 family protein. Members of this uncharacterized protein family are found exclusively in bacteria. Neighboring genes in various genomes are also uncharacterized or may annotated as similar to restriction system proteins. [Hypothetical proteins, Conserved].	0.000525758
NC_021658.1|WP_044989129.1|9966301_9966928_-|JAB-domain-containing-protein	gnl|CDD|377189	pfam04002, RadC, RadC-like JAB domain. A family of proteins present widely across the bacteria. This family was named initially with reference to the E. coli radC102 mutation which suggested that RadC was involved in repair of DNA lesions. However the relevant mutation has subsequently been shown to be in recG, where radC is in fact an allele of recG. In addition, a personal communication from Claverys, J-P, et al, indicates a total failure of all attempts to characterize a radiation-related function for RadC in Streptococcus pneumoniae, suggesting that it is not involved in repair of DNA lesions, in recombination during transformation, in gene conversion, nor in mismatch repair. Computational analysis, however, provides a possible function. The RadC-like family belong to the JAB superfamily of metalloproteins. The domain shows fusions to an N-terminal Helix-hairpin-Helix (HhH) domain in most instances. Other domain combinations include fusions to the anti-restriction module ArdC, the DinG/RAD3-like superfamily II helicases and the DNAG-like primase. In some bacteria, closely related DinG/Rad3- like superfamily II helicases are fused to a 3'-5' exonuclease in the same position as the RadC-like JAB domain. These conserved domain associations lead to the hypothesis that the RadC-like JAB domains might function as a nuclease.	1.6156e-29
NC_021658.1|WP_148314951.1|9963843_9964212_+|TerB-family-tellurite-resistance-protein	gnl|CDD|143583	cd07311, terB_like_1, tellurium resistance terB-like protein, subgroup 1. This family includes several uncharacterized bacterial proteins. The prototype of this CD is tellurite resistance protein from Nostoc punctiforme that belongs to COG3793. Its precise biological function and its mechanism responsible for tellurium resistance still remains rather poorly understood.	1.86446e-09
NC_021658.1|WP_020738916.1|9976817_9977747_-|FAD-binding-domain-containing-protein	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	9.23354e-49
NC_021658.1|WP_080682778.1|9968358_9968694_-|phage-integrase-N-terminal-SAM-like-domain-containing-protein	gnl|CDD|131303	TIGR02249, Integrase/recombinase_E2_protein., integron integrase. Members of this family are integrases associated with integrons (and super-integrons), which are systems for incorporating and expressing cassettes of laterally transferred DNA. Incorporation occurs at an attI site. A super-integron, as in Vibrio sp., may include over 100 cassettes. This family belongs to the phage integrase family (pfam00589) that also includes recombinases XerC (TIGR02224) and XerD (TIGR02225), which are bacterial housekeeping proteins. Within this family of integron integrases, some are designated by class, e.g. IntI4, a class 4 integron integrase from Vibrio cholerae N16961. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Other].	4.10452e-16
NC_021658.1|WP_020738905.1|9964753_9965083_-|hypothetical-protein	gnl|CDD|181700	PRK09209, PRK09209, ribonucleoside-diphosphate reductase subunit alpha.	0.00394398
NC_021658.1|WP_044986430.1|9978222_9980556_-|xanthine-dehydrogenase-family-protein	gnl|CDD|376913	pfam02738, Ald_Xan_dh_C2, Molybdopterin-binding domain of aldehyde dehydrogenase.	2.17122e-164
NC_021658.1|WP_080682449.1|9973439_9974303_+|reverse-transcriptase-like-protein	gnl|CDD|260008	cd09276, Rnase_HI_RT_non_LTR, non-LTR RNase HI domain of reverse transcriptases. Ribonuclease H (RNase H) is classified into two families, type 1 (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). Ribonuclease HI (RNase HI) is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes. RNase HI has also been observed as an adjunct domain to the reverse transcriptase gene in retroviruses, long-term repeat (LTR)-bearing retrotransposons and non-LTR retrotransposons. RNase HI in LTR retrotransposons perform degradation of the original RNA template, generation of a polypurine tract (the primer for plus-strand DNA synthesis), and final removal of RNA primers from newly synthesized minus and plus strands. The catalytic residues for RNase H enzymatic activity, three aspartatic acids and one glutamic acid residue (DEDD), are unvaried across all RNase H domains. The position of the RNase domain of non-LTR and LTR transposons is at the carboxyl terminal of the reverse transcriptase (RT) domain and their RNase domains group together, indicating a common evolutionary origin. Many non-LTR transposons have lost the RNase domain because their activity is at the nucleus and cellular RNase may suffice; however LTR retrotransposons always encode their own RNase domain because it requires RNase activity in RNA-protein particles in the cytoplasm. RNase H inhibitors have been explored as an anti-HIV drug target because RNase H inactivation inhibits reverse transcription.	1.07155e-24
NC_021658.1|WP_148314151.1|9969131_9970205_+|hypothetical-protein	gnl|CDD|376162	pfam18739, HEPN_Apea, Apea-like HEPN. Apea-like HEPN nuclease. In epsilonproteobacteria embedded in R-M operons.	0.000664211
NC_021658.1|WP_020738919.1|9980670_9981309_-|nucleotidyltransferase-family-protein	gnl|CDD|378957	pfam12804, NTP_transf_3, MobA-like NTP transferase domain. This family includes the MobA protein (Molybdopterin-guanine dinucleotide biosynthesis protein A). The family also includes a wide range of other NTP transferase domain.	6.80473e-19
NC_021658.1|WP_020738908.1|9966924_9967575_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	6.30105e-15
NC_021658.1|WP_020738920.1|9981305_9982268_-|XdhC-family-protein	gnl|CDD|224886	COG1975, XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones].	5.08065e-42
NC_021658.1|WP_020738909.1|9967739_9968021_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.8581e-09
NC_021658.1|WP_044989132.1|9977743_9978226_-|(2Fe-2S)-binding-protein	gnl|CDD|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	4.71799e-73
NC_021658.1|WP_020738921.1|9982518_9987345_+|AAA-family-ATPase	gnl|CDD|226459	COG3950, COG3950, Predicted ATP-binding protein involved in virulence [General function prediction only].	5.95133e-17

Protein sequences

>NC_021658.1|WP_148314152.1|9971253_9971862_+|hypothetical-protein
MTFIDVLGWKGIWLRRTGPEVVRHLKHLVGTAEKMVRGADETTVLSISDTIVLLTIGEPKTGLQLHGDVTTQLICDSISYGLPLRGATACGQFFVESPSILVGPAVDEAASWHEATDWIGVIQTPSAFLAYDGIGPWREDHAPVKGGGVRPFKIPCVDWPRVWRKQGRTRQELQRYFSAMGPFDTSVATKYTNTLLFYGDDP
>NC_021658.1|WP_020738911.1|9970495_9971155_+|hypothetical-protein
MQLTDDERALAEDIRQRLTTILTSLQQNAKINPKDIDVMGAQAHRLHMSLKGHGHEPQHHKYMLKNRGVPPTDPEFYKHVHPVEDLLGFLANQNANDNPVDLTIGKSFSFPVYSRRFGNVDSYTVTRTSSGWTFHHVQDVSAGRDARVGGKSGTGLFALLDHDSINYPEELPGYFEWLWEQAADRGLDAAEVQSALTDLADWVSLCEKNSPHGVFESFK
>NC_021658.1|WP_148314151.1|9969131_9970205_+|hypothetical-protein
MKGWSCYPIWGIELADNAIGLEKPIFGDATLVTRAYVQTFAPADPVAASMLSGGGVRQALDKSSFAGSAPIERLIDIPPGAFIAVRRSKPEDAVRYAESVRALLTATSVLTSGQGKGFAMTPLPLHWAAVPSYVRLNQAGQLQIDYHMVVNNFIHLQPIRVTHKQLRDSWNSGSTIQGSWTISREHALSKALIGDWGSLSPLRRRVRGAACTLARAMESTDPTLSTLFTVVALESLLKEGASGFAEMAELAACIFEGPNGPADIARLFGNRHKVAHEAISPAGTADHAKEIFAAWALVFLAAMSAEALTSPAQLLEHLRGRVLARRIAKRLRENGRTDLAAEVENEAKQLPKKGPTS
>NC_021658.1|WP_080682778.1|9968358_9968694_-|phage-integrase-N-terminal-SAM-like-domain-containing-protein
MGAEEVTAFRDELAVARRPAASTQNQALCARLFLYKRVLDLQIPRLEALERARRPEHLPSVLSRLDIRTIQTLLGHNDGRTTMIDTHIIDRGPLGVISPLGRRPPRQRGAP
>NC_021658.1|WP_020738909.1|9967739_9968021_+|helix-turn-helix-transcriptional-regulator
MHDPRLQEVLNFIGANVRRIRLKRGMTQQELADAAAVGLRYLKKVEHAQTNVGMAGLVKLADALGVRPGVLLRPRELPPVKRGRPRKARPREP
>NC_021658.1|WP_020738908.1|9966924_9967575_-|sigma-70-family-RNA-polymerase-sigma-factor
MRTVRPRPEEGQEIDPPSRRRRRTAARGRLGRPPEPRHASSHPAVYLEATALLEHRPLIRSTLRARGVRAADLDDVTQETVLGAFRSMRAGRFRPSLDQPPGDALRAWLAAVASRQASHYRDKAYRRYEVAAVEPHRLAAFAAPSPEPRLVARGLLRAFHRLRAELRDVLALTATGLTMREIAEALAIPRPTVATRLRLARRLFARALTRRRRWPR
>NC_021658.1|WP_044989129.1|9966301_9966928_-|JAB-domain-containing-protein
MTSATVDAPAATAAEIPTATEAGLIEMVLGIPAVGPRILGTAALPSLGRLSPAALAERTQIALLDATRLAAAFELGRRAHAARARRGALLTDAARVARTFGPKLASLVHEELWIASLDSHGRVRETRMLARGVDDAVYAGRATILRAALDMAAVSFVLAHNHPSGDPTPTAEDEAMTQQLRDLSHELNVPLRAHVIVTPSGRYSAVLE
>NC_021658.1|WP_148314150.1|9965167_9966226_-|hypothetical-protein
MVALLRMARGKRAATTRDGRAAQRQRRARVYTAWHPVLVALLEHVVPEGWYQCISEFQLAREPLRVDIVILRRRRRGAPPAPRLLTSVVGELAEHTLVHFKGPTDELERDDARMLLAYALQYLVVAEIDDPAAVALRVVAPRVTQRFLGALRSLGCALATTGPGTHEGRLGVFPLRVVETVPATARAGEHLLYTVTPGMVADPGGIPALSPEEIAVFWALLEHVEQVRHPLPGQRKRHMKDEKRVLESFEQALARIVARLPPEKVLQSYEPEQVLRSYAPEQRLAGLAPEQRLAGLSEAEAVLALPDTTLRALSQEYLATLPRETQAAIQERLLATSKRRPARQRKTRTLPR
>NC_021658.1|WP_020738905.1|9964753_9965083_-|hypothetical-protein
MATGRVFTVPVVDLVLPAPMRLVIARQCSSSAAAIERDVGLGFGWTHALAWEIEERRRGLALWRGDGTREPIPSLEPGQSIRLSPARSIAREDGCYVLRDEHGHLPGAG
>NC_021658.1|WP_148314951.1|9963843_9964212_+|TerB-family-tellurite-resistance-protein
MAIVKSLVSVAWADGEFHDAEREMVEGLIAAFEANEDQAKEIRAYAAERRTLDDVPLGELGGEDRRALLQHAVLLTFVDGEQHEAEKQYIAALREKLEIPEAESEPIIQAAEARARRLLTLL
>NC_021658.1|WP_080682449.1|9973439_9974303_+|reverse-transcriptase-like-protein
MNSQKERAGASRFWVTCYTDASFTPIAAGWGVWLRSTRGRIVRHGACPPYVSSANEAELAAIFAGVYLARKVWGDAVRGLVVYTDSQAAVRFLSDEALKPRIQRNAPAVARLRERIRTFSNEHGIELDLRWVKGHQRTNTVRAYLNARCDQLAGAARAVAQRSEKRTVAEKRGREAGSAVAEKSNGTPNAGKPGVERLPRRSSKQKNRERRHRARERNRAKKVASVSDRARPRAFELPVASGLDIGLGGQCARNRARSKSDDDERAEQAVASGALPNFAPFSRAMRR
>NC_021658.1|WP_044986428.1|9974455_9975322_-|hypothetical-protein
MGIELSQEQLAVLKETRAVATPAEFRTLLDTARPEMDRIVREVMEPSQPISTTLTELRDLYLSVVQYEAPLASKAYGPERRALLRAAIQLLDTANLWFGEGKRTGAYQVRPVDQVIKASRPWRARLKAFADQAFAFEPDVADQFADVNTSGTLTEETSDLAMLLRLAEQHQTRLSPVGLTEEFLREGSALLDEVSGRDLLGILGLRNREEAMVLRNSIVTYATLLGHEARAAGVNACWDIPEGKRRFSAASFRNALRRLRPKRRGTASAPDEPAPPEPPPVEPTGAPV
>NC_021658.1|WP_020738915.1|9976613_9976817_+|hypothetical-protein
MNYDIGMICQACGCVTIFQAGTDTPRRCARCDDVDMDPPPAPPSRERPARSCGRSRRPEAAQLDGME
>NC_021658.1|WP_020738916.1|9976817_9977747_-|FAD-binding-domain-containing-protein
MSIADLGLFEMRRVSGLGALCELVAEQAARGAAVALLAGGTDWVVEQELRPPLGAPAPGGAGPAAPPLVVDVSRLSDLRGISIYAGTHGDTLRVGAATTYLEMRRSDAIEERAPLLARMSRDVGAVQIQARGTLGGNLATASPAADGVAALAAYDATVVVQSVRGERRIPMSALQTGYKRTSRAPDEVIVAVEIALPERGSPWYWRKVGARRAQAISKVALAGVAEVRSGRLARLGLGMASVAPTTALLPTVRALCLSRPLGELTVAEVDAAVAQDIAPIDDVRSTRAYREHCARGVVRELLRQLGAPV
>NC_021658.1|WP_044989132.1|9977743_9978226_-|(2Fe-2S)-binding-protein
MKVSLVVNGSPREVDLPPLSRLLDALRGPLGLTGTKEGCAEGECGACTVLIDGDPVNACLVAIGQCEGRRVTTVEGLGAAGHLSPLQRCFIEEGGAQCGICTPGMLISAEALLARNADPSELEVREALAGNLCRCTGYQRIVESVRAAAALRRGGGGEAP
>NC_021658.1|WP_044986430.1|9978222_9980556_-|xanthine-dehydrogenase-family-protein
MATSPPASASAVGISVPRADGPPKVTGASRYVDDIPAMPGEIFGRTVRSPVPRGILRGVRFDPAFDWSDVTVVLAEDVPVNVVALILDDQPILGTGKVNHAYEPIVLLGCEDRLKLARAVQAVALDIDPLPPVLDMRASLEGKEILWGADNVIKRYLITKGRPDAERERGEAAIDAALARCEVVVTGTYASHHQEQLYIEPQGVIAWWDEAGAHATGSIQCPFYVHKAFLKAFGLSPDRIHITQSVTGGGFGGKEEYPSIIALHAALLAKKSGRPVRMIYDRTEDIEATTKRHPASCEITSGCDRDGTLRALKIRILMDGGAYATLSQVVLSRGALHASGAYRWDDVWIEATAVATNTPPNGAFRGFGAPQTIWAIERHLDRVARELGRDPLDLKAKNVLRPGDSTATGQVLHASVAGEECIAKAIEASGYRQKRAAGPVVRGRVARGVGLSVFMHGAGFTGSGERYYKGKVALDLAPGGRLRIRTASTDIGQGTETVFRQIAADAAGLPLDRVEFAVPCTTTVPDSGPTVASRTVMVVGSILEAAARELSGRVRAEQEAARQRAAEEGRAGAAAPSFEEAADLLLAREGQVTSLKQYEPPGYVRWDDEAYKGDAYPCFGWACDVAEVEVDLDTFEVTVVDFWSAADVGKAIHPVMCKGQIEGGSLQAIGWALSEEIVWQGGKIRNPRMTNYIIPTSLDAPPFHVDLVEAPFPFGPGGGAKGIGEMPMDGGAPAIAAAVEHATGIAAWALPLTPERLFEAARGAAAPRPAAGGGERA
>NC_021658.1|WP_020738919.1|9980670_9981309_-|nucleotidyltransferase-family-protein
MKTVITIVLAAGAGKRLGGPKALLAWPAAEKGGPERPLAIAHAEARLAAESARVLVVVRTSVFHALLAHVRPGIDLVSWTAPDDLGPAGSLAVAAPRIGDADAVVVTPVDVPPASAATVARLLARLDAGAPSAAAPLAVRPRHLGRGGHPVVLRAEALQRYLEADPPPLRDHLRALGDRCVDEEVDDPGVLHDLNVPVDVLRVLGGPPRFLA
>NC_021658.1|WP_020738920.1|9981305_9982268_-|XdhC-family-protein
MPDPSQVIPRTALPHDVLRAALGALEAGRRVVLASVVARHGSAPSTPGQKLCLFEDLTAIGTIGGGAVERAALGIMGRALDELATTPKLETFRLGPSLGMCCGGSVDVLIEPMLPAVHVLVIGAGHVGAFAAPLLASLGFRVTLCDARAAAADPARVLPSAPLAGVSPPHDGAQQGPMPAIAEQVRLVLADHDDPEVTAGLPRDLGEAAALVMTHDHGLDQEAIAWALARGFGYIGGVGSRAKAARTRARLEAKGVAEGDVARVRMPVGLDIGARSPAEIGVALAAELIAWRSGRQRARWSSASSASSGAVAPAGEEQAR
>NC_021658.1|WP_020738921.1|9982518_9987345_+|AAA-family-ATPase
MAPLSARRSKPRPPRPSKSPASAPPPDCLAEWVARAGLGDDVLDALVAWLAKQILSDQFAKLEQGGHREGGIPLRKVFVDLPITARPVHDADPRGSEGSGDRRLFVRMLLRQKAAPLASPAGRLETRRAPGEPGNLPARERRGFLVVGGPGQGKSTLGQLACQVHRAALLAPFLERLQPAQRDVVRAFTETASRKEIGWPLAPLFPVRIVLPEAAAWLARQDGAAEARPAQLLRLLSAQAESRGIRLSPEVLERLLGRASLLLVLDGLDEVGAAEDRARLVAATRDLLAALGGAGARGLVVATTRPQGYTGELEGIGVPLATVYLAPLQRGEALAYGRKLADAKLPGQPDNCARVVRGLESAASEAATARLLTTPLQVTILAALVQRMGRVPSERWGLFERYFETIYDREVERGTYAAPLLRDHRMHIGRIHRRVGLLLQVESESAGGTEARMSRERLEAVADAVLREDDVDEEARAGLVRRVVRAAEERLVFLVEPEPGKFGFEIRSLQEFMAAWALTEEGDAPVPIEERLLRIAKAPTFRAVALFIASKLFTKEPSLRALADRVCRALDEDPDDAAARAVRAGAVLALDILEEGSALNQPKYTRQLMERACGLLDLPPCEEQARLARVATGEAAAKVLRAAVEERLRDPAADSALGAWIALVEAAKLGEAWAAETGKAAWQALEDATDVVAAWGELGEFLPVPEWLADRIEETPDKVPPHAISGQFMPRSWSAGMCWVEAFIGLMRIHSIAEASTMPWLRLAWIEVSAARDPRWAAIAAFQDPPAHWRPWVLAARFMERPTAATLAETLRRLSSEPSAWEQRNELASAVSWPLAACLTSADAPHDLLSYADLAESGRLSDAHEWVAAQDQWPEQLDEKAFLDSMSRTLPWEQTALSVAPPPGGVHFSEGVGTARRGWSSRFRAALEKVRSRSLQAHLTSALAVFPGGAPGDRIDGLSWAEVERWSELHGELLVPAVLEAIRSKRIDSWIDGLDRLGRRRKLHMPWHGLTPVIAASLCRLYVEHPDRYGLLYWLRACLRRGHSQFLDEKTRSAVLHAMTKHPVPEPALRADAALIRIPLGDVSRDQVSALLDTVAAQAAQEPGLWWDVIRRAEQSPLPSATREMLLVDLLRRPELPWRHASFAVRALRSSLQTRRTGLADPAAWTRLRLPLPLPLVHTPAQHGFALPESPVVLSRVQVQHIRGVAGVTLELAPPPAPDQGQWVVLLGPNGAGKTTLLRSVVLALRSLSNPKIWPRGTFATPWRANGAPAGPSAITVHLAGGRTFSATVQKNGSELFAQEPRDQPTPFPIFAYGCRRGSALGGAAREVHLGEDDGPEIATLFDEGAPLVHAETWLKEWDGAAARDPEKNAAVYDAVRRALQELLAVDALVVRDRQVLVSGPSVGTDVPFAALSDGYLTAAGWFLDLVARWIELAHKHLGSLNDGLLRRMTGLVLLDEIDLHLHPRWQLEVIPRVKRLLPKMSFIVTTHNPLTLVGARPEEIWTLSLEDGRVRAERGTEAPMLLTGGQIYGRYFGIQDVYPSEIGEALRRYGFLSGDPLRTDEEQAEMDRLRATLKANGIEPGWEEVPREAPRPARPRPRGQRAKAAPR
>NC_021658.1|WP_020738922.1|9987341_9988211_+|hypothetical-protein
MIRIHRGAEPDELRRVRLERLPELARIARTRPPRSEEIDGYRIAAGPLWRAQNFKCCYCERKIPKLYNDVEHYRPKASATREPGSQDRHGYWWLAFTWTNLLFACPSCNRTGKNDRFPLDAGSVALVAKEAPPGKEKPLLLDPAEHHGIEHIEFVFGVIPARATSAGVPPGWSARKHWWPRARGGSLTGDWTIRVCGLDSSEHIELYDDHVDKEARPAARDLEEALKRRRDVTAAFDQAMRLLQPGKPFMGLSYDALRLLVPGDALAPWNLAWPEPREAGRSPGRTRRR

Crispr_ID: NC_021658_45

• CRISPR_ID: NC_021658_45
• CRISPR_location: 10062088-10062489
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 9 spacers

Consensus repeat of NC_021658_45

Consensus_repeat	Method
TGCCTCGTCCAGACCGTTTCCGGT	CRT

spacers of NC_021658_45

>45.1|10062112|18|NC_021658|CRT
CCGCCGGAGCCTCCCGAC
>45.2|10062154|18|NC_021658|CRT
CCGCTGGAGGCTTCCAGC
>45.3|10062196|18|NC_021658|CRT
CCGCTGGAGGCTCCCAGC
>45.4|10062238|18|NC_021658|CRT
TCACCGACGACAGCCAGC
>45.5|10062280|18|NC_021658|CRT
CCGCTGGAGGCTCCCAGC
>45.6|10062322|18|NC_021658|CRT
TCACCGACGGCAGCCAGC
>45.7|10062364|18|NC_021658|CRT
TACCCCAGGGCAGCCAGC
>45.8|10062406|18|NC_021658|CRT
TACCCCAGGGCAGCCAGC
>45.9|10062448|18|NC_021658|CRT
TACCCCAGGGCAGCCAGC

CRISPR arrays and Neighbor proteins around NC_021658_45

CRISPR arrays

The CRISPR arrays of NC_021658_45

>merge|NC_021658|45|10062088-10062489|CRT
TGCCTCGTCCAGACCGTTTCCGGTCCGCCGGAGCCTCCCGACTGCCTCGTCCAGACCGTTTCCGGTCCGCTGGAGGCTTCCAGCTGCCTCGTCCAGACCGTTTCTGGTCCGCTGGAGGCTCCCAGCTGCCTCGTCCAGACCGTTTCCGGTTCACCGACGACAGCCAGCTGCCTCGTCCAGACCGTTTCCGGTCCGCTGGAGGCTCCCAGCTGCCTCGTCCAGACCGTTTCCGGTTCACCGACGGCAGCCAGCTGCCTCGTCCAGACTGTTTCCGGTTACCCCAGGGCAGCCAGCTGCCTCGTCCAGACTGTTTCCGGTTACCCCAGGGCAGCCAGCTGCCTCGTCCAGACTGTTTCCGGTTACCCCAGGGCAGCCAGCTGCCTCCTCCAGACCGCTTCCGGT

>NC_021658|45|8|10062088-10062489|CRT
TGCCTCGTCCAGACCGTTTCCGGT	CCGCCGGAGCCTCCCGAC
TGCCTCGTCCAGACCGTTTCCGGT	CCGCTGGAGGCTTCCAGC
TGCCTCGTCCAGACCGTTTCTGGT	CCGCTGGAGGCTCCCAGC
TGCCTCGTCCAGACCGTTTCCGGT	TCACCGACGACAGCCAGC
TGCCTCGTCCAGACCGTTTCCGGT	CCGCTGGAGGCTCCCAGC
TGCCTCGTCCAGACCGTTTCCGGT	TCACCGACGGCAGCCAGC
TGCCTCGTCCAGACTGTTTCCGGT	TACCCCAGGGCAGCCAGC
TGCCTCGTCCAGACTGTTTCCGGT	TACCCCAGGGCAGCCAGC
TGCCTCGTCCAGACTGTTTCCGGT	TACCCCAGGGCAGCCAGC
TGCCTCCTCCAGACCGCTTCCGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_044989138.1|10054876_10057264_-|glycosyltransferase-family-39-protein	unknown	unknown	gnl|CDD|224720
NC_021658.1|WP_020738982.1|10068586_10069090_+|phosphohistidine-phosphatase-SixA	unknown	unknown	gnl|CDD|224973
NC_021658.1|WP_080682453.1|10062852_10064076_-|ArsA-family-ATPase	unknown	unknown	gnl|CDD|223082
NC_021658.1|WP_148314155.1|10064247_10064790_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738974.1|10059165_10060947_+|ribosome-biogenesis-GTPase-Der	unknown	unknown	gnl|CDD|234628
NC_021658.1|WP_187346079.1|10061530_10061848_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738985.1|10071601_10072336_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080682779.1|10061844_10062063_+|hypothetical-protein	unknown	unknown	gnl|CDD|234628
NC_021658.1|WP_020738975.1|10061042_10061525_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738984.1|10070441_10071428_+|HDIG-domain-containing-protein	unknown	unknown	gnl|CDD|131739
NC_021658.1|WP_020738981.1|10067390_10068569_+|recombinase-RecA	unknown	unknown	gnl|CDD|236476
NC_021658.1|WP_020738971.1|10054249_10054747_-|TIGR02266-family-protein	unknown	unknown	gnl|CDD|274060
NC_021658.1|WP_044989139.1|10058215_10059169_+|GTPase-Era	unknown	unknown	gnl|CDD|234624
NC_021658.1|WP_020738969.1|10052573_10053191_+|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|183566
NC_021658.1|WP_148314157.1|10072467_10073898_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738970.1|10053210_10054221_+|zf-HC2-domain-containing-protein	unknown	unknown	gnl|CDD|235906
NC_021658.1|WP_020738980.1|10064861_10065596_+|hypothetical-protein	unknown	unknown	gnl|CDD|226870
NC_021658.1|WP_020738983.1|10069494_10070268_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738968.1|10051241_10052024_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_049949732.1|10065647_10067012_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_044989138.1|10054876_10057264_-|glycosyltransferase-family-39-protein	gnl|CDD|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	8.21245e-10
NC_021658.1|WP_080682453.1|10062852_10064076_-|ArsA-family-ATPase	gnl|CDD|223082	COG0003, ArsA, Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning].	1.7263e-32
NC_021658.1|WP_049949732.1|10065647_10067012_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.68736e-74
NC_021658.1|WP_020738974.1|10059165_10060947_+|ribosome-biogenesis-GTPase-Der	gnl|CDD|234628	PRK00093, PRK00093, GTP-binding protein Der; Reviewed.	0
NC_021658.1|WP_080682779.1|10061844_10062063_+|hypothetical-protein	gnl|CDD|234628	PRK00093, PRK00093, GTP-binding protein Der; Reviewed.	1.36405e-28
NC_021658.1|WP_020738981.1|10067390_10068569_+|recombinase-RecA	gnl|CDD|236476	PRK09354, recA, recombinase A; Provisional.	0
NC_021658.1|WP_020738984.1|10070441_10071428_+|HDIG-domain-containing-protein	gnl|CDD|131739	TIGR02692, putative_tRNA_nucleotidyltransferase, tRNA adenylyltransferase. The enzyme tRNA adenylyltransferase, also called tRNA-nucleotidyltransferase and CCA-adding enzyme, can add or repair the required CCA triplet at the 3'-end of tRNA molecules. Genes encoding tRNA include the CCA tail in some but not all bacteria, and this enzyme may be required for viability. Members of this family represent a distinct clade within the larger family pfam01743 (tRNA nucleotidyltransferase/poly(A) polymerase family protein). The example from Streptomyces coelicolor was shown to act as a CCA-adding enzyme and not as a poly(A) polymerase. [Protein synthesis, tRNA and rRNA base modification].	5.79527e-42
NC_021658.1|WP_020738971.1|10054249_10054747_-|TIGR02266-family-protein	gnl|CDD|274060	TIGR02266, gmx_TIGR02266, Myxococcus xanthus paralogous domain TIGR02266. This domain is related to Type IV pilus assembly protein PilZ (pfam07238). It is found in at least 12 copies in Myxococcus xanthus DK 1622.	1.53762e-21
NC_021658.1|WP_044989139.1|10058215_10059169_+|GTPase-Era	gnl|CDD|234624	PRK00089, era, GTPase Era; Reviewed.	2.12787e-137
NC_021658.1|WP_020738969.1|10052573_10053191_+|RNA-polymerase-sigma-factor	gnl|CDD|183566	PRK12513, PRK12513, RNA polymerase sigma factor; Provisional.	8.39458e-91
NC_021658.1|WP_020738970.1|10053210_10054221_+|zf-HC2-domain-containing-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	1.76468e-05
NC_021658.1|WP_020738980.1|10064861_10065596_+|hypothetical-protein	gnl|CDD|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	7.09069e-36
NC_021658.1|WP_020738968.1|10051241_10052024_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	1.54446e-09
NC_021658.1|WP_020738982.1|10068586_10069090_+|phosphohistidine-phosphatase-SixA	gnl|CDD|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	3.5831e-24

Protein sequences

>NC_021658.1|WP_080682779.1|10061844_10062063_+|hypothetical-protein
MTHPPPTHGGRAPRLLLVTQAETSPPLFVVVASDPEKLHFSYRRYVANQFRQTFGLEGVPVRVKYKERRWRG
>NC_021658.1|WP_187346079.1|10061530_10061848_+|hypothetical-protein
MSFRRATIRARAPEAQNLEDRLFQEMRAPSEDPDAQPIIVAEPPDPAPITRLFVIWDEWGALSQQERSEIITNAYLRAHGQADALRLSVAMGVTRAEAVRMGLTS
>NC_021658.1|WP_020738975.1|10061042_10061525_+|hypothetical-protein
MQDLILAAEERYWDAYELAVQGRDFAAIYLAGFTAEMLLKTAGFRFNGIALGQETGPLLGPARAFGQARFPAIDHESYHSLRFWLAYLEHKRADAGRPLDPALLNELRVRVARAYETWWVAMRYRSSATPDVRAVGNLAEVLTLLEDVGWIMNNHTLLWS
>NC_021658.1|WP_020738974.1|10059165_10060947_+|ribosome-biogenesis-GTPase-Der
MSAAKPAPSRGTRRGQGAAGGGRATKTGDGPAKRGGVAPRKGAASGKSAVAPRKSAPASGKSAVAPRKSAPGKAAAASGRAAAAPGKNAVAPGKAAAGGARKGSGSSKGRAAFEQSGHNPAEDRDELAAELADEALEAAEDAAADAPAPPPSAGIVALVGRPNTGKSTLFNRLVGKRIAIVHDEPGVTRDRHYGDVTSRGRRFTLVDTGGFDPESDDPMRQGIKRQIDLAIAEADVIVCVLDAVTPVTPSEHAELGLLRRAGKPVIYVANKADSPRAEAEAAELYRLGMDRLIPISALHGRGISDLEMAIEAALPKEPAAPEASAEGALRIAIIGRPNAGKSSLVNRIAGEERMLVDAQPGTTRDPIDTLAERDGKRFLLIDTAGIRRKAKVAKEDSAVEAVSVMHAIRAMERAEVVLLLCDAAEGVAEQDAKILGLAVDRGCGVVIGLNKIDLLDRKTLAKAEQDARDKLAFVAWAPIVQVSARSGRGVAKLLETVGQVADAYRKRVPTGELNRFFEQILLTHPPPTHGGRAPRLFFVTQAETSPPLFVVVASDPEKLHFSYRRYVSNQLRQAFGLEGVPVRVKYKERRRRG
>NC_021658.1|WP_044989139.1|10058215_10059169_+|GTPase-Era
MPRRSGRVALVGRPNVGKSTLLNAALGHPLAIVSPTPQTTRDAILGVVHHGPAEIALLDTPGLHRPRTELGRVMNQAAREAARSADVIVFVTEAPDPARLPRRAKEGEDGPPFAPHPGDLALLADLGSEAPVVFVLNKVDRVRDKARLLPLLDAFGQIRDFAAIVPISALREDGVQRVLDEVAKLCPERAWGFAPDELTDRPTRFFAAEYVREQILRATKAEVPHASAVQIERYVEPTGDGALHIDATIHVERPGQKKILIGAAAEQLKRIGTEARLRIEELVGRQVNLKLWVRVTPEWRESLQTLEELGYNKGETS
>NC_021658.1|WP_044989138.1|10054876_10057264_-|glycosyltransferase-family-39-protein
MDLADPAGQLPTLTDLGMGELGFTSMALGFRLLGLHDWAGRLPLALWGLAGALVLYEFLARLVDRKAGLYGVAVLVTMPLYVMQARTMLGDIVTMAALTMAFCGLTGALLEGGRGARRGAVLAPAAWSAVGILGLAAGYLSRGLLIGVAVPALGAGLTWIVLRTSGAWPAPERPRPTLGDLVGGAALLLGVAAAAKGLLVLASSSADAPLPRALGVALLKKPPVESTFDLTLRQLGHALFPWSAFLPFAVGRLFRAPAAAQGAAAGLDREAGVRIALVVTSALAYGAFALLAPHAGALPFSGPALLAAIAALAVRDLERGAPSSRALAVGCSVLAFVLYRDLVLSPDRALSVFSVDKPVFPKSFEEEAASAMRFVLIAFAGLVALTWFEEQPREIDRGLRAWARRLDADVRAGAEELARIWGGNLLFLLIVLEAALVGVGAMIFVGKRIGWGTVARMPNHLAAYGMNAWWALPLLLAVGPVVLIAVRDAFRFVVARASVPRALGTPLAGLVAGFALSFWYYPALAAQLSPKEVFESYASLRKPGEPLATLGVRSRAAAYYQGGEVASFNDAPRAFAWLTASAAEGSADSAAAPGARRWLVVKSDELPRLNSLFRKQHGRNLPVLDGRSSQIVLASNELGGRPNESWLSRVVLDEPVAPANPLDAMFDDQLEVLGWELTDDEGQQASSVVPQKSYHLRTFFRVHRPITGNWKMFVHIDGFQRRYNGDHAVIEGRYPMSLWQPGDVIVDDHELKLEPNFTPGDYALYVGFFSGDARFEVTRGPEHENRIRAGVIRVR
>NC_021658.1|WP_020738971.1|10054249_10054747_-|TIGR02266-family-protein
MTGGRGDSNHPPDTPGGSSATPAQNGAYGDAGHTGEDAECEIPPDSLNRRSSERLDVTWLVDCETDDTFLYASITNISEMGIFVRTTQPLSIGTRLTLRFSPPGAEGSYVLEGTVQWVNEVRPLHDNPNPGMGIRFVDLTPDDRERIVDTIRTIAYIRDAPVRSN
>NC_021658.1|WP_020738970.1|10053210_10054221_+|zf-HC2-domain-containing-protein
MDCEKFDQHVMDALYDELDELTHAAMKRHMDSCARCASAFAGLRAARDAGPLPLEEPSEELEARILEAVEVAQKKTPFRRKALRALAWAGSHAMRPQLAMAALFVLVIGSSLLLLRPKTGVAPVRVTEWGQPASDLHEPPSVPAPTALAAPADDGDGRRMAEAKASEPPRPMAEAAKEKSARGAAAPEDGARLALRDAQTLQRTSGCAAAVGKLDEVGAQYPGTPAAHAAMWEAARCHQAAGETEKARELLLALRSAKGYGDRAEQMLAGLEANAARSQAHNAAPVAASPAPASAPRPAAASRPAAKPAAPPRADEQGPAQAAPPDAVPPDAVMAR
>NC_021658.1|WP_020738969.1|10052573_10053191_+|RNA-polymerase-sigma-factor
MVPISREEVTDEALMMRFQGGDRAAFAGLVRRHKTPIYNFILRQVRGPAVAEDLVQDVFVKIVQSASDFKHEARFTTWAYAIARNVCIDHLRKMSLRRHPSLDQGSGDGDGPTLGERTADPAPQAAVDRVAIGAEMGQLIVRAVESLPHEQREVFLLREIGHVPFKDIAQIVGVPENTVKSRMRYALERLQEALSEYEDYARALR
>NC_021658.1|WP_020738968.1|10051241_10052024_-|hypothetical-protein
MAVPAFAQSPGGASGKAAAPAASVAPAASAPANAAQAAPATGAAAASPGTTAAPAASPGATAAPAAGAAAPAMDGPTYAVRLRDLEQRIDELKEQIRRSHTRLSLLSDTILSGGGAGSRASIRFNNELSSAFRVTRVLIVLDGAVQYNKTDQSGALAEQTEIPIFNGSVPPGDHTLQVLVNLQGNGYGVFSYLRGYRFEVRSSHSFTAVEGKTINLQAVAFEKGGVTTPLEERPAVRFVEKIVSGLSDASGQPAAAAGGK
>NC_021658.1|WP_080682453.1|10062852_10064076_-|ArsA-family-ATPase
MPGPLAPPRNTPPAAHAPRRADDAGLAPLLASRRVILCVGCGGVGKTTTTAALGLAAARRGKRVLCLTIDPARRLSQSLGIEEMKTEAQTIEPARFARAGVDVPGSMTVMMLDTKSTFDGLVASLAPSPEQRDRILGNVLYKYISTSLAGTQEYMAMEKLYAVRSDPSYDLVLLDTPPTANALDFLDAPERLVGAIDSAATRWFVQAFQSSGKLSLNLLARSTAAVLRGIGKLTGSGFLEQIAAFISEMNAVFGGWKQRADAVASALRGPDVAYVLVTTPDPLCVREVLFFADRLREQDMRRDAFVVNRVHPVYGALPGAAEIAAALDGSGLALGPGAAARLLQAAEDETRMGKLDHLNLIALEAALEDEQTGGSVRVDVPAFPYDIYDVAGLARIADVLAPLPGAA
>NC_021658.1|WP_148314155.1|10064247_10064790_-|hypothetical-protein
MSLSLSNQQLVPEPGSNGGAGGQRGDQQGGRAERPEGRGALSAEGGAAAAGEAAPASERRRRRSDDPITALHYQLSTTRSEANLDVVVLVDDSGCLVAGAGAWPACEELAAYAPLLANPDAVQSAAVGSRIAALTAEVEVQSLAVAGGEVLLCGRGGTAERGASIARAAAGCLRILRAAA
>NC_021658.1|WP_020738980.1|10064861_10065596_+|hypothetical-protein
MRGFIDLHCHWVAGIDDGARTVEESFALLTALRGAGFDTVVATPHMRPGMFDNTRQSLRAAYDATCDALRRAGDARGLPALDLSSEHFFDDVVFQRLLDGSALPYPGGRAALVEFPTRSFPVRVAERIFDLSRRKLRPVIAHPERYEPVFDDCSSLDPLLDAGAVLLLDVAALTGKYGRTPRRAAEQLLEEGYYYAACSDAHAARDVADVRGGIDALFARVGEEEATFMLIDGPRAILEGTVDV
>NC_021658.1|WP_049949732.1|10065647_10067012_-|serine/threonine-protein-kinase
MGHTFHVGGGGRFFPGFSLGRYEFVLRVAAGETGEVWAGRLRREHGFQKLFAIKVLHPELSPDPDAVRMFLEEAALAARIRHPNVVPVVDLGEEGGTLFYVMEWVSGEPLSAVLRAARRRPAPVLAAARLAYQICAALDAAHELRDEVGNPRELLHYDVSPDNVLITSEGLVRLVDFGIAKFEEERLSERRPSLRGDGGRVFAAAAGGEGGALLFRSSAPYMAPEHIRGQPCDRRADLFGVGVLLYELLSGAHPFQADDSESTMTHIASERPAAPLSSRAVPSRRGFAERLSAAPPPEPIPPALDRLVSEALAKSPTARTATAAQLMRALEEAVPGAAHPGNDALVAGWIGQVLGNASHLRTQQLRAALESLDPGGGAADEAEPLPAWRRWAQAAWAFGAAVLGVALAGTTAVKDSPLPPASFTAPAGPRVDTAASSLGAPPRRRGAATTPHRR
>NC_021658.1|WP_020738981.1|10067390_10068569_+|recombinase-RecA
MSDEKNTKQKSAALELAIASVEKEYGKGAIMRLKDGQTLHDEVAAVPSGSLGLDIALGIGGYPRGRIVEIYGPESSGKTTLTLHAIAAIQRAGGTAAFIDAEHALDVNYAKKLGVKTDELLISQPDYGEQALEIADMLVRSNAVDIIVVDSVAALVPKAEIEGDMGDSHVGLQARLMSQALRKLTGTTSRSQCLLMFINQIRMKIGVMFGSPETTSGGNALKFYASVRLDIRRIGAIKEAAAGGKEPAVVGNRTRVKVVKNKMAPPFREVEFDILYGHGISHSGDVIDLATEASIIEKSGSWFSFQGERIGQGRENARSYLEQHPAVLEKIESMVLAKHGISRAGASAAANGAAAAGPKGGAAAAEPPAQAKGRGEAAPSGQDARRAPGKTN
>NC_021658.1|WP_020738982.1|10068586_10069090_+|phosphohistidine-phosphatase-SixA
MHLYVMRHGPAEDRAASGRDADRRLTPEGRDRVERVAIELHRIRGGAPLSRVLASPLARARETAEIAAPRCGAPEVEVRDELSVDADLPLALVAALARGGADALLVGHQPNVEHLVRTLVDTSGRGSPGLVLRGFTTALIVALEPDPAPRAQDRWRVVRILDPRELA
>NC_021658.1|WP_020738983.1|10069494_10070268_+|hypothetical-protein
MWPRVSRAVVRVPDPRHHPIHIDLPSGQPQIYVHEGARQALVRRLELAQKRPVLLSVTDNYRQMISSSLREGILQARVHHMFLDAPAVVQDALVRYVVNQDRAASLVVGQYIDENGHRIRASRPVSTPLSTQGRTHDLLTLSQKVNHTYFGGVVDALITWGKRTKARKPRRTIKLGSYSAVERLIRIHPVLDRPWVPRYFISYVIYHEMLHHVMPASHGNGRRMLHPPQFLARERLFRDYERSLAWERDHVGRLLRT
>NC_021658.1|WP_020738984.1|10070441_10071428_+|HDIG-domain-containing-protein
MWKDSVQEILTQEASPKRAMEALEWAVQRAERAEPAQPEAAAEPRPSTRVIPGRPADFKAAAAIYLPDVRKLLDRIMMSDDAEAGLDALLESGALAAMLPEVEAMVGFGDGEWRHKDVWKHTKQVVRQAVPRLEVRWAALLHDIGKTRTRTISPTGEVHFFGHAEVGARMFDKIDRRLPLFAKEEALKGSIRFLILHHLRASQYDPSWTDSAVRRFAKEMGGCLNDVLDLSRADITTKRPEKKRKGLKQINDLAERVLHVQAEDAVVPPLPSGIGDAIMRAFGLPPSRRVGEVKRALEQAVEAGEVPSHQEADVYIAFLRENAARFGL
>NC_021658.1|WP_020738985.1|10071601_10072336_-|hypothetical-protein
MAADKPVKRKRKGSGSTGQGGEVLLRQRTDPRSERRFEPKASLELALTLLGMSVAALLAGAGVYGQWFRGEEAGAHPAAPYLLVGALLLGAAAGLFGQWSMKPVRVGDAGVALENGPGEIERIGWSEVTGLLLSESALTVQGGGTVIAVPLRAHLAAASRVLSEARKRIPGRVADIKEDALPAPDDAAGEVRPLEPPQVAGLHCKATDKLIAFEADARLCGRCGELYHKDGVPPRCITCEAPLR
>NC_021658.1|WP_148314157.1|10072467_10073898_+|hypothetical-protein
MRSMPDAATYVLPALSIGLAALVFLGPGAQRMATGVRVWGAPVAGSEALALRIEGVRRLHGADDPAALPAIEVSATSGGTALAGWSGSTGKDGIGEALLRAGGGLKAPVMVRIRRGGDALLEQEVPLSPPLPAEASALPGAAHASALPGAAHGELRLRVTVARGAMAAPFPEPVRVAVETEDGAPVPGARVEASAVGAELGGLGSGPAQITADARGAAELTIRPLAHTVELTLRAARPGSAAPPGARGASGSWEGRLPVIPGAIWLDPAGLAGERPELRLTSPAPKPYAYVSIGGEHGRLLGAIVPLAADGGGFFSGTLALPDGQPPGAAGWAAVASDPYEQGAGTVAWPLSPAASPVAPRRVTLLADGVPAAEARERARASRARRAGLVVLGAAGVAEMLLLALRARTARRRLTAHLAAASGGEGEDGADGAPLSREDRGRLLATVRAEPVLSVLALAALVGLSFAAVAALATFR

Crispr_ID: NC_021658_46

• CRISPR_ID: NC_021658_46
• CRISPR_location: 10090674-10090773
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_46

Consensus_repeat	Method
GGCGCGCCCGGCGCGGCCGTCTCCG	CRISPRCasFinder

spacers of NC_021658_46

>46.1|10090699|49|NC_021658|CRISPRCasFinder
CCACGCAGGCGTCACGCCCTGACACACGAACGTCATAGACAGCCGTGCT

CRISPR arrays and Neighbor proteins around NC_021658_46

CRISPR arrays

The CRISPR arrays of NC_021658_46

>merge|NC_021658|46|10090674-10090773|CRISPRCasFinder
GGATCGATCAGCGCGGCGATCTTCGCCACGCAGGCGTCACGCCCTGACACACGAACGTCATAGACAGCCGTGCTCGCGATCGCGCCGCGGCCGTCGACGG

>NC_021658|46|40|10090674-10090773|CRISPRCasFinder
GGATCGATCAGCGCGGCGATCTTCG	CCACGCAGGCGTCACGCCCTGACACACGAACGTCATAGACAGCCGTGCT
CGCGATCGCGCCGCGGCCGTCGACGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020739001.1|10093846_10094920_-|DUF72-domain-containing-protein	unknown	unknown	gnl|CDD|376655
NC_021658.1|WP_020739009.1|10099500_10100421_-|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl|CDD|234712
NC_021658.1|WP_020739008.1|10099234_10099519_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|369571
NC_021658.1|WP_020739005.1|10097691_10098045_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314159.1|10095322_10095727_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738994.1|10082167_10084594_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380537
NC_021658.1|WP_020739007.1|10098332_10098722_-|RNA-binding-protein	unknown	unknown	gnl|CDD|240845
NC_021658.1|WP_044989145.1|10079084_10080173_-|hypothetical-protein	unknown	unknown	gnl|CDD|379721
NC_021658.1|WP_020738995.1|10084731_10085709_+|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257
NC_021658.1|WP_020739010.1|10100472_10101837_-|hypothetical-protein	unknown	unknown	gnl|CDD|224001
NC_021658.1|WP_020738998.1|10087566_10088727_+|homogentisate-1,2-dioxygenase	unknown	unknown	gnl|CDD|226039
NC_021658.1|WP_148314160.1|10096598_10097525_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738997.1|10086415_10087567_+|VOC-family-protein	unknown	unknown	gnl|CDD|273528
NC_021658.1|WP_020738996.1|10085705_10086377_+|maleylacetoacetate-isomerase	unknown	unknown	gnl|CDD|273527
NC_021658.1|WP_020739000.1|10089299_10090403_-|deoxyhypusine-synthase-family-protein	unknown	unknown	gnl|CDD|376661
NC_021658.1|WP_044986444.1|10102761_10103985_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738992.1|10080325_10081732_+|NAD-dependent-succinate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143418
NC_021658.1|WP_148314158.1|10081750_10082125_+|DUF1801-domain-containing-protein	unknown	unknown	gnl|CDD|378058
NC_021658.1|WP_020739011.1|10102009_10102765_-|ferritin-like-domain-containing-protein	unknown	unknown	gnl|CDD|153097
NC_021658.1|WP_020738999.1|10088739_10089285_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020739001.1|10093846_10094920_-|DUF72-domain-containing-protein	gnl|CDD|376655	pfam01904, DUF72, Protein of unknown function DUF72. The function of this family is unknown.	1.45552e-60
NC_021658.1|WP_020739008.1|10099234_10099519_+|cupin-domain-containing-protein	gnl|CDD|369571	pfam07883, Cupin_2, Cupin domain. This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel).	6.61825e-12
NC_021658.1|WP_020739007.1|10098332_10098722_-|RNA-binding-protein	gnl|CDD|240845	cd12399, RRM_HP0827_like, RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins. This subfamily corresponds to the RRM of H. pylori HP0827, a putative ssDNA-binding protein 12rnp2 precursor, containing one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain). The ssDNA binding may be important in activation of HP0827. .	8.69468e-28
NC_021658.1|WP_020738994.1|10082167_10084594_-|substrate-binding-domain-containing-protein	gnl|CDD|380537	cd06314, PBP1_tmGBP, periplasmic sugar-binding domain of Thermotoga maritima glucose-binding protein (tmGBP) and its close homologs. Periplasmic sugar-binding domain of Thermotoga maritima glucose-binding protein (tmGBP) and its close homologs from other bacteria. They are members of the type 1 periplasmic binding protein superfamily which consists of two domains connected by a three-stranded hinge. TmGBP is specific for glucose and its binding pocket is buried at the interface of the two domains. TmGBP also exhibits high thermostability and the highest structural similarity to E. coli glucose binding protein (ecGBP).	1.8412e-66
NC_021658.1|WP_020739009.1|10099500_10100421_-|undecaprenyl-diphosphate-phosphatase	gnl|CDD|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	4.29316e-98
NC_021658.1|WP_044989145.1|10079084_10080173_-|hypothetical-protein	gnl|CDD|379721	pfam14907, NTP_transf_5, Uncharacterized nucleotidyltransferase. This family is likely to be an uncharacterized group of nucleotidyltransferases.	0.00431653
NC_021658.1|WP_020738995.1|10084731_10085709_+|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.68038e-39
NC_021658.1|WP_020739010.1|10100472_10101837_-|hypothetical-protein	gnl|CDD|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	0.000883122
NC_021658.1|WP_020738998.1|10087566_10088727_+|homogentisate-1,2-dioxygenase	gnl|CDD|226039	COG3508, HmgA, Homogentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	3.39508e-46
NC_021658.1|WP_020738997.1|10086415_10087567_+|VOC-family-protein	gnl|CDD|273528	TIGR01263, 4-hydroxyphenylpyruvate_dioxygenase, 4-hydroxyphenylpyruvate dioxygenase. This protein oxidizes 4-hydroxyphenylpyruvate, a tyrosine and phenylalanine catabolite, to homogentisate. Homogentisate can undergo a further non-enzymatic oxidation and polymerization into brown pigments that protect some bacterial species from light. A similar process occurs spontaneously in blood and is hemolytic (see . In some bacterial species, this enzyme has been studied as a hemolysin. [Energy metabolism, Amino acids and amines].	4.70657e-81
NC_021658.1|WP_020738996.1|10085705_10086377_+|maleylacetoacetate-isomerase	gnl|CDD|273527	TIGR01262, Maleylacetoacetate_isomerase, maleylacetoacetate isomerase. Maleylacetoacetate isomerase is an enzyme of tyrosine and phenylalanine catabolism. It requires glutathione and belongs by homology to the zeta family of glutathione S-transferases. The enzyme (EC 5.2.1.2) is described as active also on maleylpyruvate, and the example from a Ralstonia sp. catabolic plasmid is described as a maleylpyruvate isomerase involved in gentisate catabolism. [Energy metabolism, Amino acids and amines].	1.81527e-83
NC_021658.1|WP_020739000.1|10089299_10090403_-|deoxyhypusine-synthase-family-protein	gnl|CDD|376661	pfam01916, DS, Deoxyhypusine synthase. Eukaryotic initiation factor 5A (eIF-5A) contains an unusual amino acid, hypusine [N epsilon-(4-aminobutyl-2-hydroxy)lysine]. The first step in the post-translational formation of hypusine is catalyzed by the enzyme deoxyhypusine synthase (DS) EC:1.1.1.249. The modified version of eIF-5A, and DS, are required for eukaryotic cell proliferation.	2.37862e-102
NC_021658.1|WP_020738992.1|10080325_10081732_+|NAD-dependent-succinate-semialdehyde-dehydrogenase	gnl|CDD|143418	cd07100, ALDH_SSADH1_GabD1, Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like. Succinate-semialdehyde dehydrogenase 1 (SSADH1, GabD1, EC=1.2.1.16) catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde (SSA) to succinate. SSADH activity in Mycobacterium tuberculosis (Mtb) is encoded by both gabD1 (Rv0234c) and gabD2 (Rv1731). The Mtb GabD1 SSADH1 reportedly is an enzyme of the gamma-aminobutyrate shunt, which forms a functional link between two TCA half-cycles by converting alpha-ketoglutarate to succinate.	0
NC_021658.1|WP_148314158.1|10081750_10082125_+|DUF1801-domain-containing-protein	gnl|CDD|378058	pfam08818, DUF1801, Domain of unknown function (DU1801). This large family of bacterial proteins is uncharacterized. They contain a presumed domain about 110 amino acids in length.	1.15677e-06
NC_021658.1|WP_020739011.1|10102009_10102765_-|ferritin-like-domain-containing-protein	gnl|CDD|153097	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	1.84596e-08

Protein sequences

>NC_021658.1|WP_020739000.1|10089299_10090403_-|deoxyhypusine-synthase-family-protein
MSSSKHSRSSHRHLGDGVEDKLVPLEALDPLKIGSFDDMLRAMSRTAFSGRALGEACDVLETMVRDEDCLVVATFSGAMTVAKMGVVIVRMIEAGMIDCIISTGALMAHGLSEAVGLTHYKANPGISDETYFEKGYNRVYDTLEMEKNLNAIEVFVRKELDKLDSGSPWSSEIICRQLGKALAEMGDSPGVLRSAYLRNVPVYVPAFTDSEMGLDVATWMLRKVKAQHGDKPGFDVWREAVPPSYNPFLDLLSYARLVRTKKRLGIFTIGGGVPRNWAQQVAPFYDIVGDRLDIEVDHPRFQYGVRICPEPVHWGGLSGCTYSEGVSWGKFTAPQEGGRFAEVYADATVAWPLLVRALLERLGKMPK
>NC_021658.1|WP_020738999.1|10088739_10089285_-|hypothetical-protein
MRAAMPRPPRLLEALLSLAAAGGALLAAGCPSQEERVCDLMCDCSGCSEARYRECVDKTDAARQAAVEASCPAILDEYLACLDAEAECKNDVLSYDGCEGQERDLRQCGVFVFRTVCEQANERLMGCGQGAPFGSGPEACPEEVACNAECIVRVSCDGLNGIDFEEAQRFNDCNSSCFLKP
>NC_021658.1|WP_020738998.1|10087566_10088727_+|homogentisate-1,2-dioxygenase
MLDRVVAGSVPPKHHVALRSGAGELRYEECLTRAGFDGPYTIAYHERRPHEHRLARAEHGFAPPVAAPPRPLAKRHYRSQDLPRRGGPAIDCRVPLLFNDDVVIGLAQPDAADPVYFANADADELLFVAQGGGVLRTMLGDLRFEQDDYVVVPKGLFHRFLPDAAPQRWLSIQAADVHLPRQWRNEVGQLRMDAPYSHRDFRRPTFVGPLDEGIRALVVKRGGAFHGFACERSPLDVVGWDGTVYPFAFPIERFQARVGLVHLPPDWHGTFAARGALVCSFVPRPVDFHPEAIPCPYPHSSVDCDELLFYCRGNFTSRRGVGPGSISHHPAGVPHGPHPGAYEASLGSRATSELAVMLDTIRPLAATPAALEVEDPGYQDSFIAGP
>NC_021658.1|WP_020738997.1|10086415_10087567_+|VOC-family-protein
MAKVESIGIKRVEALHYYVRDLERSRRFYTEKLDFQETAASSPELSAAAAQRSVVFQAGECAIVCSQPIGEGGRAWRYLRKHPDGVGTIIFEVEDIDRAFRLLDGRGGTPIDEIHRVTEGGGTFASFSITTPFGDTTFRFVERHGYPALFPGCVAHDAPRGGENRFGIARFDHITSNFQTMAPALLWMEHVLGLEPFWHIAFHTNDVAKDAGHGSGLRSAVMWDPGSGVKFANNEPYRPHFKSSQINVFNEEHRGDGVQHAALAVDDILAAVRAMRARGVEFMPTPAAYYDLLPERLQRLGVGQLDEDVAALRELEVLVDGDGARSYLLQIFLKESSGTHRDPDAGPFFFELIQRKGDRGFGAGNFRALFESIERQQKAEGRG
>NC_021658.1|WP_020738996.1|10085705_10086377_+|maleylacetoacetate-isomerase
MSAALTGLTLYGYWRSSCSWRARIALAHKGIEHAYRPVNLVRDGGEQLHDDYRAKNPMAQVPLLEFEQGGAVRRVSQSVAIIELLEELFPAPPLLPADPYLRAKARQLVEMINSGTQPMQNTATLKYVRDELGGDERAFGRRFIASGLAAFQAAASELCGRFCVGDQVTVADVFLVPQLYNARRYDVDLAPLSTLTRIEAACMALPAFQAAHADRQVDAVAGA
>NC_021658.1|WP_020738995.1|10084731_10085709_+|fumarylacetoacetate-hydrolase-family-protein
MKLASLRGPGRDGTLVVVRRDGLAYAPAGAAFPTLQAALDDWARAEPALRRIADDIERGGAAVAPLVVEELAAPLPRAYEWIDGSAYIHHIELVRRARGAEPPETLTTDPLVYQGGSGVLLGPTDDIVVRDEAWGLDFEAEVCAVLGDTPQGTRRDEAHRHIRLFLLANDVTLRNLVPAELAKGFGFFCSKPATAFSPFAITPDELGDAFRDGRVHLRLRSTYNGALVGDPEAGPEMHFSFFDLIEHIARTRSFTAGTLLGSGTVSNRDPARGVSCLAEKRMLEILAHGAARTPFMKPGDTIMIEMLNRSGESLFGRIAQRVVAG
>NC_021658.1|WP_020738994.1|10082167_10084594_-|substrate-binding-domain-containing-protein
MNTGLDVFSTLHHLVQRAMASLPGAQRGGLLVRAGRRLVYTATVGLDGILPGKLRTPSDGGLLSASAPFGPAAAPEAARGPCLVPAAAWYRAHLPEVAERPGWPPEGAYVQVVPVPLFGGPGAYLALEQPDDAPLSGPYRALVESVAESAGAALERRGLFEEKAQVAQELRLLEEVLSSVAESVDLVELIETLADGIRSVQTGPRWGTIDLAILEDAGRERAADARRTLRLYKAPRRPMTAYWNNVRDGALAAGRDLRVAVGFRSGVGADPASQEALFEEGLRRGVKCIAVAPIDPAALEPLIRRAVAAGVAVVAIDSPTVQGSAAPVYIGTDNRAAGRLAGEVMLRLLPQGGLVVTQAASFAVSNAGERLAGFREAVAGSAIRIGAPLENHFDPARGVELATAALRDDPEIAGAFGVCSENGPSFGAASVTLGRSGDLKLVAFDLITPTVAMLQDGVVHAAIVQREYDMGYRCVQVLYDMATRGVEAALEALPASRFIDTGLDVVTVERTPFSVALSDHLAMSSARRITNRRLGASGRGRPLEFLVIGMAERESLVDDERAPVAEDSLVGRVMSSCSSLVIDTASSEYQHFSDVAEARWNGARTLVGVPLLSREAVLGVLMLSSPRPDACSANDLALIERVASVAAVVLENARLLSRIKERTRELESLSRRQEALLDTIAAMSSPAVPIAPGVLVMPIVGTLDAQRSGRFIEAMLQEISEHKARAVIIDVTGMAVVDASAASHIAQAARAAAMLGSEVVLVGIAPEAARLMVDQGLDLGGIVTRSTLELGFSYALGKTGGRVVYRRS
>NC_021658.1|WP_148314158.1|10081750_10082125_+|DUF1801-domain-containing-protein
MVSEDPAVAALLSEYPPAAQQLTLRVRKLLLRIIPDVHEHVFPGWRIISFRMGDAQKHQICWLAPQRFGVNLGFEHGAELPDPGGLLTGDAKRARNVHIRSAKDVDVAKIAALVAAAVELRRDR
>NC_021658.1|WP_020738992.1|10080325_10081732_+|NAD-dependent-succinate-semialdehyde-dehydrogenase
MNTAIATINPATGETLETFEPLSPAALEQKVARAHATFRSFRQTPVAERAQKLRRAAEILEAEKEQLGRLMTLEMGKTIGSAVAEAQKCATVCRYYADNAERQLAPEEVATDAGKSYVAFHPLGPVLAIMPWNFPFWQVFRFAAPALVAGNVGLLKHASNVPRCALAIEDILRRAGFPEGAFQALLTGTDVVPRLLADPRIAAATLTGSENAGRSVGAHAGKHLKKVVLELGGSDPFIVLPSADLNAAVGTAIKARIINNGQSCIAAKRFIVHESVVPEFEQRFVAAMRRLRVGDPMDPSVDVGPLATAQIAAELEEQVRASVAAGALLLTGGKRLKGPGNYFPPTVLTDVRSPSPAADDELFGPVAAVFRVADLDEAIHMANSTRFGLGASAWTRDPQERERLIDELEAGQVFINGMVVSDPRLPFGGVKMSGHGRELSSYGLREFVNIKTVWIAKDERPRGLPATE
>NC_021658.1|WP_044989145.1|10079084_10080173_-|hypothetical-protein
MPRRRAQGGGGGGSPSHVLFITQSGMARSGSPAVFDAERAGSARATRAGERAALAPPATDDAAGLLSRAGELEVRVRALESLLCAGVPFMVAGAYAFFAYTGIFRDTKDLDVMLEEREVPAAFRALERIGFETALLDPRWIGKAYAGDRFIDLIFSSSNGLAVVDGGWFEHARPATILGHSCLIAPVEEIIFTKAFVDERERYDGADVNHLIYACGDEMDWERLLDRFGPHWEVLFAHVTLYRFVYPGARSRVPEWLVAELCRRTLEQSRAGDAPLRVCRGNLISRRQYAHDYEELGLVAAPAGPAPEPEVALGSPCRKRRRSGAARRRVGNTGAQAREGAPGGADRLGAEAEAARLRKPGS
>NC_021658.1|WP_020739001.1|10093846_10094920_-|DUF72-domain-containing-protein
MHEAALRDPPRSPSEETPHQHEDRLARASALAGCAPVPARWGNVLAGTAGWTDPTLAKSQRFYPKGASSPEQRLKFYASQFPVVEVNSTYYALPATAMVAQWVQRTAPDFVFNMKAFAPLTQHPVEPARLPADVQRALPPALLDRRRLYPGDLPAEARDVLWERFRQAVEPLRQARKLGYALFQFPPWFTATRGNVRVIEDCRARMEGIPLAVELRHASWGEPDRIERVVDFLRDLDAFYVIVDEPQGKENSMPPTPLVADPRLAVVRFHGRRAETWGASVSVNEKFRYVYDPAELDPWAETVARLSQEAERVHAIFNNCVSDYAVLGAKGLMALLARRAESPDRELAPEQAASTVH
>NC_021658.1|WP_148314159.1|10095322_10095727_+|hypothetical-protein
MYSANRRRNIEREERMLLRGKREQAAGKLLHRVPDLTSLNLEIREARPDAAKNDTQYIRRVVVEHAAALFEMPCSYSSCDNGGYDVTQEVLSALASRTARFEGECVCRGSCGSAFCSRVLRYVATATYRSSPQA
>NC_021658.1|WP_148314160.1|10096598_10097525_+|hypothetical-protein
MPAGASSTGAQGGVGGGAMQGSSSGTGGGPLVSSHYTLSEYVGPQIWTQLTRTAAVDAADRLFVTDGQTVFVVEDGVPSIYLSPADLQPANADAGIISMDVGPDDRLYILDRGVPAQILVSRGPHDVSILHGDLSAARTFPALLAVESPDRIFVVSHYDGLFEVTPNGIDLLYGESAIDASGCAAEDLAVSQDGRLFYLPGCNGSPLLSGLTDGSGVGILKHEDALDEYYFWMFGGIARNPPGGVMVNLVGTIYHIGTDGTATELNTTPTLNDVTADWIDFHARPIEVGPTGNVYVISTETIYRAVPD
>NC_021658.1|WP_020739005.1|10097691_10098045_-|hypothetical-protein
MKRAAPSQGALPEPATDRDSAAPPTERQQFIEQSATAVGQAWAERWRQDLHREGRPTAGGWPGTLREARTQVEIALPGELLRRKMPAITGVERELAARTAYASARDEWRRHIEPETP
>NC_021658.1|WP_020739007.1|10098332_10098722_-|RNA-binding-protein
MGNRLYVGNLSFSTTRETLESAFASAGEVREIAMPTDRETGQPRGFAFVTMGSVQAANSAISQLNGALLDGRPLKVNEAQERPARGGGGGFGGGGGYGGGGGGGYGGGGGGYGGGGGGRGGRGGGRDRY
>NC_021658.1|WP_020739008.1|10099234_10099519_+|cupin-domain-containing-protein
MDTTTRDEVLKRWRARGFHGGLWTDPPGRVWEDFVHDDDELLMVLEGELELTLAGKTLVPRIGEEIEIPAGVVHTVRNRGATTARWLYAYGRLG
>NC_021658.1|WP_020739009.1|10099500_10100421_-|undecaprenyl-diphosphate-phosphatase
MFWFDAVLLGVLEGLTEFLPVSSTGHLILLGAWLGHESEAAKTLDIVIQLGAVLAVVVYFRERLAVTVRGIFRRDPDSLRLALALAFAFFPAALVGLLFHKAIKAHLFGPGPVAVALIAGGFLMIGVESARRRRPDQGAPRVEDVTLQRALAIGVAQCFSLWPGASRSMATIVGGQLSGLSTAAAAEFSFLLAIPTLGAATVFDLAKNGRALLDAPGGAAALAVGLAVSFAVALLVIAVFLRYLKRYGLAPFGWYRIALGAVVLWLWLASRTAPVDAGAAAEPAPGGDVAASAGALARAGDHPSRP
>NC_021658.1|WP_020739010.1|10100472_10101837_-|hypothetical-protein
MRRPALGPRDGALGVLFMLEQLRLQLGGRHEEPKVAPEVTDVVVLVPGFLGFDHFGGFFYFADRVCGALRGALEVKLGRPGLVPVIPVTSRPTASLAECQASLIVFLKKVVQQFPSASLHLVGHSTGGVHAQLLTSARPQGKDRWDEEDLDPVSGWRPRIRSVVSLCAPHWGTYLAHSDLARLVGSGVEPGSVTAIPPLFNLLRLTVVESALSAFDLTFATVTELWGFFLDVGDNRKLIDALTPERMAEVRDRDRSAGPRHPARLRSFVTMAKASDDSDPFFVDLHKRAANTASGAPSRIAAEAIRRLEDELRLHAQGGPPRPCRVIKFPDSPAGPISPSSNDGVVNTAHQLVDPGSPEELAAIVVADHADVIGHYDRWELRAARPGEEVRWSRFKRGLFRSGSRFRDEQFFELYAAIADELLPAMTAGAARSSAPPPDRARPAAPSAPPPAEG
>NC_021658.1|WP_020739011.1|10102009_10102765_-|ferritin-like-domain-containing-protein
MKTETTAGMNRTGMDMSPMDSKEVIVGARIMPPSSVGDDSAIANVVAHYARREERVGTMPPPGTLKGAVKSALQMLKGEAPLVLLDKLGERLAFERAGSRLWKGVLAKYDALGSFEGGPTRAEIERIYREEAEHFLLVASVIRMLGADPTAETPLADVHGVASCGLIKVVTDPRTNLADALEAMLIAELTDNDAWDVLIDMCQGMSDEVLSQFQAARAAEARHLTMVRSWVKASVLARAQGDDAPSSRTAS
>NC_021658.1|WP_044986444.1|10102761_10103985_-|hypothetical-protein
MALDLLNEPGTPLDKQQFDWRELVSIPSSKLNDDAFTRVRIILMNGIESEAVRFSHACARMNGALQQELARIRRVEHHQQTMVNWLLPGDLSVIETTIGFEQVAIEVTASVAMNEPDEYLAQVYRFGMLEDFDHLYRYSALMDRVHGKDANNILQCYTDICPGRPTSVEHRHPDDDLRAPYDRRTAAPLSKLHALTIMASEHQTHDYYMNVGPTFADPMARQLYAEIASIEEQHVTQYESIIDPNESWLEKWLLHEATEVYNYYSCAKSESNPRIKAIWERFVDYELGQLHHVRRLFEQIEGRDSAELLPAKLPDPIEFRSHREFVRRVLQGEVHLRAVGKNIVDPTQIPESPQTLEYRERINMSGSPSEAVAAGYVWVPGTELAVQAVPGKEANGNGARVYQVRSA

Crispr_ID: NC_021658_47

• CRISPR_ID: NC_021658_47
• CRISPR_location: 10090890-10091091
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_021658_47

Consensus_repeat	Method
GGCGCGCCCGGCGCGGCCGTCTCCG	CRISPRCasFinder

spacers of NC_021658_47

>47.1|10090915|17|NC_021658|CRISPRCasFinder
GCGCGGCCGTCTCCGGA
>47.2|10090957|29|NC_021658|CRISPRCasFinder
GAGGCGCTCCACGCGCGCCTCGCTGCGCG
>47.3|10091011|56|NC_021658|CRISPRCasFinder
CGGGCGGGATCGGCACCGTGCGGCCGAGGGTCAGGTCGCGGAAGCCGAGCAGCAGC

CRISPR arrays and Neighbor proteins around NC_021658_47

CRISPR arrays

The CRISPR arrays of NC_021658_47

>merge|NC_021658|47|10090890-10091091|CRISPRCasFinder
GGCAGGAGCGGCGGGGCCTTCGCCGGCGCGGCCGTCTCCGGAGGCGCGCCCGGCGCGGCCGTCTCCGGAGGCGCTCCACGCGCGCCTCGCTGCGCGGGCGCGCCCGGCGCGGCCGTCTCCGCGGGCGGGATCGGCACCGTGCGGCCGAGGGTCAGGTCGCGGAAGCCGAGCAGCAGCGGCACGCCGGCGGCGGTCGGCTGCC

>NC_021658|47|41|10090890-10091091|CRISPRCasFinder
GGCAGGAGCGGCGGGGCCTTCGCCG	GCGCGGCCGTCTCCGGA
GGCGCGCCCGGCGCGGCCGTCTCCG	GAGGCGCTCCACGCGCGCCTCGCTGCGCG
GGCGCGCCCGGCGCGGCCGTCTCCG	CGGGCGGGATCGGCACCGTGCGGCCGAGGGTCAGGTCGCGGAAGCCGAGCAGCAGC
GGCACGCCGGCGGCGGTCGGCTGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020739001.1|10093846_10094920_-|DUF72-domain-containing-protein	unknown	unknown	gnl|CDD|376655
NC_021658.1|WP_020739009.1|10099500_10100421_-|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl|CDD|234712
NC_021658.1|WP_020739008.1|10099234_10099519_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|369571
NC_021658.1|WP_020739005.1|10097691_10098045_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314159.1|10095322_10095727_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738994.1|10082167_10084594_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380537
NC_021658.1|WP_020739007.1|10098332_10098722_-|RNA-binding-protein	unknown	unknown	gnl|CDD|240845
NC_021658.1|WP_044989145.1|10079084_10080173_-|hypothetical-protein	unknown	unknown	gnl|CDD|379721
NC_021658.1|WP_020738995.1|10084731_10085709_+|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257
NC_021658.1|WP_020739010.1|10100472_10101837_-|hypothetical-protein	unknown	unknown	gnl|CDD|224001
NC_021658.1|WP_020738998.1|10087566_10088727_+|homogentisate-1,2-dioxygenase	unknown	unknown	gnl|CDD|226039
NC_021658.1|WP_148314160.1|10096598_10097525_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738997.1|10086415_10087567_+|VOC-family-protein	unknown	unknown	gnl|CDD|273528
NC_021658.1|WP_020738996.1|10085705_10086377_+|maleylacetoacetate-isomerase	unknown	unknown	gnl|CDD|273527
NC_021658.1|WP_020739000.1|10089299_10090403_-|deoxyhypusine-synthase-family-protein	unknown	unknown	gnl|CDD|376661
NC_021658.1|WP_044986444.1|10102761_10103985_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020738992.1|10080325_10081732_+|NAD-dependent-succinate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143418
NC_021658.1|WP_148314158.1|10081750_10082125_+|DUF1801-domain-containing-protein	unknown	unknown	gnl|CDD|378058
NC_021658.1|WP_020739011.1|10102009_10102765_-|ferritin-like-domain-containing-protein	unknown	unknown	gnl|CDD|153097
NC_021658.1|WP_020738999.1|10088739_10089285_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020739001.1|10093846_10094920_-|DUF72-domain-containing-protein	gnl|CDD|376655	pfam01904, DUF72, Protein of unknown function DUF72. The function of this family is unknown.	1.45552e-60
NC_021658.1|WP_020739008.1|10099234_10099519_+|cupin-domain-containing-protein	gnl|CDD|369571	pfam07883, Cupin_2, Cupin domain. This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel).	6.61825e-12
NC_021658.1|WP_020739007.1|10098332_10098722_-|RNA-binding-protein	gnl|CDD|240845	cd12399, RRM_HP0827_like, RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins. This subfamily corresponds to the RRM of H. pylori HP0827, a putative ssDNA-binding protein 12rnp2 precursor, containing one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain). The ssDNA binding may be important in activation of HP0827. .	8.69468e-28
NC_021658.1|WP_020738994.1|10082167_10084594_-|substrate-binding-domain-containing-protein	gnl|CDD|380537	cd06314, PBP1_tmGBP, periplasmic sugar-binding domain of Thermotoga maritima glucose-binding protein (tmGBP) and its close homologs. Periplasmic sugar-binding domain of Thermotoga maritima glucose-binding protein (tmGBP) and its close homologs from other bacteria. They are members of the type 1 periplasmic binding protein superfamily which consists of two domains connected by a three-stranded hinge. TmGBP is specific for glucose and its binding pocket is buried at the interface of the two domains. TmGBP also exhibits high thermostability and the highest structural similarity to E. coli glucose binding protein (ecGBP).	1.8412e-66
NC_021658.1|WP_020739009.1|10099500_10100421_-|undecaprenyl-diphosphate-phosphatase	gnl|CDD|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	4.29316e-98
NC_021658.1|WP_044989145.1|10079084_10080173_-|hypothetical-protein	gnl|CDD|379721	pfam14907, NTP_transf_5, Uncharacterized nucleotidyltransferase. This family is likely to be an uncharacterized group of nucleotidyltransferases.	0.00431653
NC_021658.1|WP_020738995.1|10084731_10085709_+|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.68038e-39
NC_021658.1|WP_020739010.1|10100472_10101837_-|hypothetical-protein	gnl|CDD|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	0.000883122
NC_021658.1|WP_020738998.1|10087566_10088727_+|homogentisate-1,2-dioxygenase	gnl|CDD|226039	COG3508, HmgA, Homogentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	3.39508e-46
NC_021658.1|WP_020738997.1|10086415_10087567_+|VOC-family-protein	gnl|CDD|273528	TIGR01263, 4-hydroxyphenylpyruvate_dioxygenase, 4-hydroxyphenylpyruvate dioxygenase. This protein oxidizes 4-hydroxyphenylpyruvate, a tyrosine and phenylalanine catabolite, to homogentisate. Homogentisate can undergo a further non-enzymatic oxidation and polymerization into brown pigments that protect some bacterial species from light. A similar process occurs spontaneously in blood and is hemolytic (see . In some bacterial species, this enzyme has been studied as a hemolysin. [Energy metabolism, Amino acids and amines].	4.70657e-81
NC_021658.1|WP_020738996.1|10085705_10086377_+|maleylacetoacetate-isomerase	gnl|CDD|273527	TIGR01262, Maleylacetoacetate_isomerase, maleylacetoacetate isomerase. Maleylacetoacetate isomerase is an enzyme of tyrosine and phenylalanine catabolism. It requires glutathione and belongs by homology to the zeta family of glutathione S-transferases. The enzyme (EC 5.2.1.2) is described as active also on maleylpyruvate, and the example from a Ralstonia sp. catabolic plasmid is described as a maleylpyruvate isomerase involved in gentisate catabolism. [Energy metabolism, Amino acids and amines].	1.81527e-83
NC_021658.1|WP_020739000.1|10089299_10090403_-|deoxyhypusine-synthase-family-protein	gnl|CDD|376661	pfam01916, DS, Deoxyhypusine synthase. Eukaryotic initiation factor 5A (eIF-5A) contains an unusual amino acid, hypusine [N epsilon-(4-aminobutyl-2-hydroxy)lysine]. The first step in the post-translational formation of hypusine is catalyzed by the enzyme deoxyhypusine synthase (DS) EC:1.1.1.249. The modified version of eIF-5A, and DS, are required for eukaryotic cell proliferation.	2.37862e-102
NC_021658.1|WP_020738992.1|10080325_10081732_+|NAD-dependent-succinate-semialdehyde-dehydrogenase	gnl|CDD|143418	cd07100, ALDH_SSADH1_GabD1, Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like. Succinate-semialdehyde dehydrogenase 1 (SSADH1, GabD1, EC=1.2.1.16) catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde (SSA) to succinate. SSADH activity in Mycobacterium tuberculosis (Mtb) is encoded by both gabD1 (Rv0234c) and gabD2 (Rv1731). The Mtb GabD1 SSADH1 reportedly is an enzyme of the gamma-aminobutyrate shunt, which forms a functional link between two TCA half-cycles by converting alpha-ketoglutarate to succinate.	0
NC_021658.1|WP_148314158.1|10081750_10082125_+|DUF1801-domain-containing-protein	gnl|CDD|378058	pfam08818, DUF1801, Domain of unknown function (DU1801). This large family of bacterial proteins is uncharacterized. They contain a presumed domain about 110 amino acids in length.	1.15677e-06
NC_021658.1|WP_020739011.1|10102009_10102765_-|ferritin-like-domain-containing-protein	gnl|CDD|153097	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	1.84596e-08

Protein sequences

>NC_021658.1|WP_020739000.1|10089299_10090403_-|deoxyhypusine-synthase-family-protein
MSSSKHSRSSHRHLGDGVEDKLVPLEALDPLKIGSFDDMLRAMSRTAFSGRALGEACDVLETMVRDEDCLVVATFSGAMTVAKMGVVIVRMIEAGMIDCIISTGALMAHGLSEAVGLTHYKANPGISDETYFEKGYNRVYDTLEMEKNLNAIEVFVRKELDKLDSGSPWSSEIICRQLGKALAEMGDSPGVLRSAYLRNVPVYVPAFTDSEMGLDVATWMLRKVKAQHGDKPGFDVWREAVPPSYNPFLDLLSYARLVRTKKRLGIFTIGGGVPRNWAQQVAPFYDIVGDRLDIEVDHPRFQYGVRICPEPVHWGGLSGCTYSEGVSWGKFTAPQEGGRFAEVYADATVAWPLLVRALLERLGKMPK
>NC_021658.1|WP_020738999.1|10088739_10089285_-|hypothetical-protein
MRAAMPRPPRLLEALLSLAAAGGALLAAGCPSQEERVCDLMCDCSGCSEARYRECVDKTDAARQAAVEASCPAILDEYLACLDAEAECKNDVLSYDGCEGQERDLRQCGVFVFRTVCEQANERLMGCGQGAPFGSGPEACPEEVACNAECIVRVSCDGLNGIDFEEAQRFNDCNSSCFLKP
>NC_021658.1|WP_020738998.1|10087566_10088727_+|homogentisate-1,2-dioxygenase
MLDRVVAGSVPPKHHVALRSGAGELRYEECLTRAGFDGPYTIAYHERRPHEHRLARAEHGFAPPVAAPPRPLAKRHYRSQDLPRRGGPAIDCRVPLLFNDDVVIGLAQPDAADPVYFANADADELLFVAQGGGVLRTMLGDLRFEQDDYVVVPKGLFHRFLPDAAPQRWLSIQAADVHLPRQWRNEVGQLRMDAPYSHRDFRRPTFVGPLDEGIRALVVKRGGAFHGFACERSPLDVVGWDGTVYPFAFPIERFQARVGLVHLPPDWHGTFAARGALVCSFVPRPVDFHPEAIPCPYPHSSVDCDELLFYCRGNFTSRRGVGPGSISHHPAGVPHGPHPGAYEASLGSRATSELAVMLDTIRPLAATPAALEVEDPGYQDSFIAGP
>NC_021658.1|WP_020738997.1|10086415_10087567_+|VOC-family-protein
MAKVESIGIKRVEALHYYVRDLERSRRFYTEKLDFQETAASSPELSAAAAQRSVVFQAGECAIVCSQPIGEGGRAWRYLRKHPDGVGTIIFEVEDIDRAFRLLDGRGGTPIDEIHRVTEGGGTFASFSITTPFGDTTFRFVERHGYPALFPGCVAHDAPRGGENRFGIARFDHITSNFQTMAPALLWMEHVLGLEPFWHIAFHTNDVAKDAGHGSGLRSAVMWDPGSGVKFANNEPYRPHFKSSQINVFNEEHRGDGVQHAALAVDDILAAVRAMRARGVEFMPTPAAYYDLLPERLQRLGVGQLDEDVAALRELEVLVDGDGARSYLLQIFLKESSGTHRDPDAGPFFFELIQRKGDRGFGAGNFRALFESIERQQKAEGRG
>NC_021658.1|WP_020738996.1|10085705_10086377_+|maleylacetoacetate-isomerase
MSAALTGLTLYGYWRSSCSWRARIALAHKGIEHAYRPVNLVRDGGEQLHDDYRAKNPMAQVPLLEFEQGGAVRRVSQSVAIIELLEELFPAPPLLPADPYLRAKARQLVEMINSGTQPMQNTATLKYVRDELGGDERAFGRRFIASGLAAFQAAASELCGRFCVGDQVTVADVFLVPQLYNARRYDVDLAPLSTLTRIEAACMALPAFQAAHADRQVDAVAGA
>NC_021658.1|WP_020738995.1|10084731_10085709_+|fumarylacetoacetate-hydrolase-family-protein
MKLASLRGPGRDGTLVVVRRDGLAYAPAGAAFPTLQAALDDWARAEPALRRIADDIERGGAAVAPLVVEELAAPLPRAYEWIDGSAYIHHIELVRRARGAEPPETLTTDPLVYQGGSGVLLGPTDDIVVRDEAWGLDFEAEVCAVLGDTPQGTRRDEAHRHIRLFLLANDVTLRNLVPAELAKGFGFFCSKPATAFSPFAITPDELGDAFRDGRVHLRLRSTYNGALVGDPEAGPEMHFSFFDLIEHIARTRSFTAGTLLGSGTVSNRDPARGVSCLAEKRMLEILAHGAARTPFMKPGDTIMIEMLNRSGESLFGRIAQRVVAG
>NC_021658.1|WP_020738994.1|10082167_10084594_-|substrate-binding-domain-containing-protein
MNTGLDVFSTLHHLVQRAMASLPGAQRGGLLVRAGRRLVYTATVGLDGILPGKLRTPSDGGLLSASAPFGPAAAPEAARGPCLVPAAAWYRAHLPEVAERPGWPPEGAYVQVVPVPLFGGPGAYLALEQPDDAPLSGPYRALVESVAESAGAALERRGLFEEKAQVAQELRLLEEVLSSVAESVDLVELIETLADGIRSVQTGPRWGTIDLAILEDAGRERAADARRTLRLYKAPRRPMTAYWNNVRDGALAAGRDLRVAVGFRSGVGADPASQEALFEEGLRRGVKCIAVAPIDPAALEPLIRRAVAAGVAVVAIDSPTVQGSAAPVYIGTDNRAAGRLAGEVMLRLLPQGGLVVTQAASFAVSNAGERLAGFREAVAGSAIRIGAPLENHFDPARGVELATAALRDDPEIAGAFGVCSENGPSFGAASVTLGRSGDLKLVAFDLITPTVAMLQDGVVHAAIVQREYDMGYRCVQVLYDMATRGVEAALEALPASRFIDTGLDVVTVERTPFSVALSDHLAMSSARRITNRRLGASGRGRPLEFLVIGMAERESLVDDERAPVAEDSLVGRVMSSCSSLVIDTASSEYQHFSDVAEARWNGARTLVGVPLLSREAVLGVLMLSSPRPDACSANDLALIERVASVAAVVLENARLLSRIKERTRELESLSRRQEALLDTIAAMSSPAVPIAPGVLVMPIVGTLDAQRSGRFIEAMLQEISEHKARAVIIDVTGMAVVDASAASHIAQAARAAAMLGSEVVLVGIAPEAARLMVDQGLDLGGIVTRSTLELGFSYALGKTGGRVVYRRS
>NC_021658.1|WP_148314158.1|10081750_10082125_+|DUF1801-domain-containing-protein
MVSEDPAVAALLSEYPPAAQQLTLRVRKLLLRIIPDVHEHVFPGWRIISFRMGDAQKHQICWLAPQRFGVNLGFEHGAELPDPGGLLTGDAKRARNVHIRSAKDVDVAKIAALVAAAVELRRDR
>NC_021658.1|WP_020738992.1|10080325_10081732_+|NAD-dependent-succinate-semialdehyde-dehydrogenase
MNTAIATINPATGETLETFEPLSPAALEQKVARAHATFRSFRQTPVAERAQKLRRAAEILEAEKEQLGRLMTLEMGKTIGSAVAEAQKCATVCRYYADNAERQLAPEEVATDAGKSYVAFHPLGPVLAIMPWNFPFWQVFRFAAPALVAGNVGLLKHASNVPRCALAIEDILRRAGFPEGAFQALLTGTDVVPRLLADPRIAAATLTGSENAGRSVGAHAGKHLKKVVLELGGSDPFIVLPSADLNAAVGTAIKARIINNGQSCIAAKRFIVHESVVPEFEQRFVAAMRRLRVGDPMDPSVDVGPLATAQIAAELEEQVRASVAAGALLLTGGKRLKGPGNYFPPTVLTDVRSPSPAADDELFGPVAAVFRVADLDEAIHMANSTRFGLGASAWTRDPQERERLIDELEAGQVFINGMVVSDPRLPFGGVKMSGHGRELSSYGLREFVNIKTVWIAKDERPRGLPATE
>NC_021658.1|WP_044989145.1|10079084_10080173_-|hypothetical-protein
MPRRRAQGGGGGGSPSHVLFITQSGMARSGSPAVFDAERAGSARATRAGERAALAPPATDDAAGLLSRAGELEVRVRALESLLCAGVPFMVAGAYAFFAYTGIFRDTKDLDVMLEEREVPAAFRALERIGFETALLDPRWIGKAYAGDRFIDLIFSSSNGLAVVDGGWFEHARPATILGHSCLIAPVEEIIFTKAFVDERERYDGADVNHLIYACGDEMDWERLLDRFGPHWEVLFAHVTLYRFVYPGARSRVPEWLVAELCRRTLEQSRAGDAPLRVCRGNLISRRQYAHDYEELGLVAAPAGPAPEPEVALGSPCRKRRRSGAARRRVGNTGAQAREGAPGGADRLGAEAEAARLRKPGS
>NC_021658.1|WP_020739001.1|10093846_10094920_-|DUF72-domain-containing-protein
MHEAALRDPPRSPSEETPHQHEDRLARASALAGCAPVPARWGNVLAGTAGWTDPTLAKSQRFYPKGASSPEQRLKFYASQFPVVEVNSTYYALPATAMVAQWVQRTAPDFVFNMKAFAPLTQHPVEPARLPADVQRALPPALLDRRRLYPGDLPAEARDVLWERFRQAVEPLRQARKLGYALFQFPPWFTATRGNVRVIEDCRARMEGIPLAVELRHASWGEPDRIERVVDFLRDLDAFYVIVDEPQGKENSMPPTPLVADPRLAVVRFHGRRAETWGASVSVNEKFRYVYDPAELDPWAETVARLSQEAERVHAIFNNCVSDYAVLGAKGLMALLARRAESPDRELAPEQAASTVH
>NC_021658.1|WP_148314159.1|10095322_10095727_+|hypothetical-protein
MYSANRRRNIEREERMLLRGKREQAAGKLLHRVPDLTSLNLEIREARPDAAKNDTQYIRRVVVEHAAALFEMPCSYSSCDNGGYDVTQEVLSALASRTARFEGECVCRGSCGSAFCSRVLRYVATATYRSSPQA
>NC_021658.1|WP_148314160.1|10096598_10097525_+|hypothetical-protein
MPAGASSTGAQGGVGGGAMQGSSSGTGGGPLVSSHYTLSEYVGPQIWTQLTRTAAVDAADRLFVTDGQTVFVVEDGVPSIYLSPADLQPANADAGIISMDVGPDDRLYILDRGVPAQILVSRGPHDVSILHGDLSAARTFPALLAVESPDRIFVVSHYDGLFEVTPNGIDLLYGESAIDASGCAAEDLAVSQDGRLFYLPGCNGSPLLSGLTDGSGVGILKHEDALDEYYFWMFGGIARNPPGGVMVNLVGTIYHIGTDGTATELNTTPTLNDVTADWIDFHARPIEVGPTGNVYVISTETIYRAVPD
>NC_021658.1|WP_020739005.1|10097691_10098045_-|hypothetical-protein
MKRAAPSQGALPEPATDRDSAAPPTERQQFIEQSATAVGQAWAERWRQDLHREGRPTAGGWPGTLREARTQVEIALPGELLRRKMPAITGVERELAARTAYASARDEWRRHIEPETP
>NC_021658.1|WP_020739007.1|10098332_10098722_-|RNA-binding-protein
MGNRLYVGNLSFSTTRETLESAFASAGEVREIAMPTDRETGQPRGFAFVTMGSVQAANSAISQLNGALLDGRPLKVNEAQERPARGGGGGFGGGGGYGGGGGGGYGGGGGGYGGGGGGRGGRGGGRDRY
>NC_021658.1|WP_020739008.1|10099234_10099519_+|cupin-domain-containing-protein
MDTTTRDEVLKRWRARGFHGGLWTDPPGRVWEDFVHDDDELLMVLEGELELTLAGKTLVPRIGEEIEIPAGVVHTVRNRGATTARWLYAYGRLG
>NC_021658.1|WP_020739009.1|10099500_10100421_-|undecaprenyl-diphosphate-phosphatase
MFWFDAVLLGVLEGLTEFLPVSSTGHLILLGAWLGHESEAAKTLDIVIQLGAVLAVVVYFRERLAVTVRGIFRRDPDSLRLALALAFAFFPAALVGLLFHKAIKAHLFGPGPVAVALIAGGFLMIGVESARRRRPDQGAPRVEDVTLQRALAIGVAQCFSLWPGASRSMATIVGGQLSGLSTAAAAEFSFLLAIPTLGAATVFDLAKNGRALLDAPGGAAALAVGLAVSFAVALLVIAVFLRYLKRYGLAPFGWYRIALGAVVLWLWLASRTAPVDAGAAAEPAPGGDVAASAGALARAGDHPSRP
>NC_021658.1|WP_020739010.1|10100472_10101837_-|hypothetical-protein
MRRPALGPRDGALGVLFMLEQLRLQLGGRHEEPKVAPEVTDVVVLVPGFLGFDHFGGFFYFADRVCGALRGALEVKLGRPGLVPVIPVTSRPTASLAECQASLIVFLKKVVQQFPSASLHLVGHSTGGVHAQLLTSARPQGKDRWDEEDLDPVSGWRPRIRSVVSLCAPHWGTYLAHSDLARLVGSGVEPGSVTAIPPLFNLLRLTVVESALSAFDLTFATVTELWGFFLDVGDNRKLIDALTPERMAEVRDRDRSAGPRHPARLRSFVTMAKASDDSDPFFVDLHKRAANTASGAPSRIAAEAIRRLEDELRLHAQGGPPRPCRVIKFPDSPAGPISPSSNDGVVNTAHQLVDPGSPEELAAIVVADHADVIGHYDRWELRAARPGEEVRWSRFKRGLFRSGSRFRDEQFFELYAAIADELLPAMTAGAARSSAPPPDRARPAAPSAPPPAEG
>NC_021658.1|WP_020739011.1|10102009_10102765_-|ferritin-like-domain-containing-protein
MKTETTAGMNRTGMDMSPMDSKEVIVGARIMPPSSVGDDSAIANVVAHYARREERVGTMPPPGTLKGAVKSALQMLKGEAPLVLLDKLGERLAFERAGSRLWKGVLAKYDALGSFEGGPTRAEIERIYREEAEHFLLVASVIRMLGADPTAETPLADVHGVASCGLIKVVTDPRTNLADALEAMLIAELTDNDAWDVLIDMCQGMSDEVLSQFQAARAAEARHLTMVRSWVKASVLARAQGDDAPSSRTAS
>NC_021658.1|WP_044986444.1|10102761_10103985_-|hypothetical-protein
MALDLLNEPGTPLDKQQFDWRELVSIPSSKLNDDAFTRVRIILMNGIESEAVRFSHACARMNGALQQELARIRRVEHHQQTMVNWLLPGDLSVIETTIGFEQVAIEVTASVAMNEPDEYLAQVYRFGMLEDFDHLYRYSALMDRVHGKDANNILQCYTDICPGRPTSVEHRHPDDDLRAPYDRRTAAPLSKLHALTIMASEHQTHDYYMNVGPTFADPMARQLYAEIASIEEQHVTQYESIIDPNESWLEKWLLHEATEVYNYYSCAKSESNPRIKAIWERFVDYELGQLHHVRRLFEQIEGRDSAELLPAKLPDPIEFRSHREFVRRVLQGEVHLRAVGKNIVDPTQIPESPQTLEYRERINMSGSPSEAVAAGYVWVPGTELAVQAVPGKEANGNGARVYQVRSA

Crispr_ID: NC_021658_48

• CRISPR_ID: NC_021658_48
• CRISPR_location: 10333320-10333398
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_48

Consensus_repeat	Method
GCGCCGTCAGGCGACCCGGAGCCCC	CRISPRCasFinder

spacers of NC_021658_48

>48.1|10333345|29|NC_021658|CRISPRCasFinder
GGATGTCGGCCTGGGTCCTGGGGCGCAGG

CRISPR arrays and Neighbor proteins around NC_021658_48

CRISPR arrays

The CRISPR arrays of NC_021658_48

>merge|NC_021658|48|10333320-10333398|CRISPRCasFinder
GCGCCGTCAGGCGACCCGGAGCCCCGGATGTCGGCCTGGGTCCTGGGGCGCAGGGCGCCGTCGGGCGACCCGGAGCCCC

>NC_021658|48|42|10333320-10333398|CRISPRCasFinder
GCGCCGTCAGGCGACCCGGAGCCCC	GGATGTCGGCCTGGGTCCTGGGGCGCAGG
GCGCCGTCGGGCGACCCGGAGCCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020739197.1|10340816_10342064_+|ferrous-iron-transporter-B	unknown	unknown	gnl|CDD|223447
NC_021658.1|WP_020739183.1|10327652_10329134_+|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPB	unknown	unknown	gnl|CDD|235292
NC_021658.1|WP_148314194.1|10321783_10323052_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739190.1|10334796_10336107_-|nickel-dependent-hydrogenase-large-subunit	unknown	unknown	gnl|CDD|225798
NC_021658.1|WP_020739185.1|10330260_10331370_-|hydrogenase-formation-protein-HypD	unknown	unknown	gnl|CDD|237892
NC_021658.1|WP_020739191.1|10336096_10336873_-|oxidoreductase	unknown	unknown	gnl|CDD|224852
NC_021658.1|WP_020739193.1|10337801_10338278_-|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl|CDD|237999
NC_021658.1|WP_020739189.1|10334347_10334800_-|hydrogenase-maturation-protease	unknown	unknown	gnl|CDD|99872
NC_021658.1|WP_020739195.1|10339826_10340072_+|ferrous-iron-transport-protein-A	unknown	unknown	gnl|CDD|377199
NC_021658.1|WP_020739194.1|10338284_10339499_-|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|379938
NC_021658.1|WP_148314195.1|10326048_10326261_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739180.1|10325331_10325481_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044989181.1|10336878_10337721_-|Ni/Fe-hydrogenase-subunit-gamma	unknown	unknown	gnl|CDD|99817
NC_021658.1|WP_020739188.1|10334001_10334343_-|hydrogenase-maturation-nickel-metallochaperone-HypA	unknown	unknown	gnl|CDD|376468
NC_021658.1|WP_020739182.1|10326288_10327656_+|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPA	unknown	unknown	gnl|CDD|234769
NC_021658.1|WP_020739198.1|10342205_10344536_+|phosphoenolpyruvate-synthase	unknown	unknown	gnl|CDD|235809
NC_021658.1|WP_020739179.1|10324286_10325099_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044986469.1|10331366_10331621_-|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	unknown	unknown	gnl|CDD|376549
NC_021658.1|WP_044989180.1|10329235_10330264_-|hydrogenase-expression/formation-protein-HypE	unknown	unknown	gnl|CDD|100033
NC_021658.1|WP_148314962.1|10323155_10323278_-|ATP-binding-protein	unknown	unknown	gnl|CDD|223679

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020739197.1|10340816_10342064_+|ferrous-iron-transporter-B	gnl|CDD|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	9.76249e-111
NC_021658.1|WP_020739183.1|10327652_10329134_+|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPB	gnl|CDD|235292	PRK04366, PRK04366, aminomethyl-transferring glycine dehydrogenase subunit GcvPB.	0
NC_021658.1|WP_020739193.1|10337801_10338278_-|cyclic-nucleotide-binding-domain-containing-protein	gnl|CDD|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	3.60517e-17
NC_021658.1|WP_044986469.1|10331366_10331621_-|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	gnl|CDD|376549	pfam01455, HupF_HypC, HupF/HypC family.	4.54468e-28
NC_021658.1|WP_044989181.1|10336878_10337721_-|Ni/Fe-hydrogenase-subunit-gamma	gnl|CDD|99817	cd06221, sulfite_reductase_like, Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is linked to ferredoxin and reduces NH2OH and SeO3 at a lesser rate than it's normal substate SO3(2-). Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to orotate coupled with the reduction of NAD+.	1.5417e-127
NC_021658.1|WP_020739191.1|10336096_10336873_-|oxidoreductase	gnl|CDD|224852	COG1941, FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit [Energy production and conversion].	8.15915e-42
NC_021658.1|WP_044989180.1|10329235_10330264_-|hydrogenase-expression/formation-protein-HypE	gnl|CDD|100033	cd02197, HypE, HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis. HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the ATP-binding domains of the AIR synthases, selenophosphate synthetase (SelD), and FGAM synthase and is thought to bind ATP.	8.32184e-165
NC_021658.1|WP_020739195.1|10339826_10340072_+|ferrous-iron-transport-protein-A	gnl|CDD|377199	pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.	1.96456e-13
NC_021658.1|WP_020739194.1|10338284_10339499_-|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|379938	pfam17179, Fer4_22, 4Fe-4S dicluster domain.	1.52972e-47
NC_021658.1|WP_020739189.1|10334347_10334800_-|hydrogenase-maturation-protease	gnl|CDD|99872	cd00518, H2MP, Hydrogenase specific C-terminal endopeptidases, also called Hydrogen Maturation Proteases (H2MP). These enzymes belong to the peptidase family M52. Maturation of [FeNi] hydrogenases includes formation of the nickel metallocenter, proteolytic processing and assembly with other subunits. Hydrogenase maturation endopeptidases are responsible for the proteolytic processing, liberating a short C-terminal peptide by cleaving after a His or an Arg residue, e.g., HycI (E. coli) is involved in processing of HypE, the large subunit of hydrogenase 3. This cleavage is nickel dependent. This CD also includes such hydrogenase-processing proteins as HydD, HupW, and HoxW, as well as, proteins of the F420-reducing hydrogenase of methanogens (e.g., FrcD). Also included, is the Pyrococcus furiosus FrxA protein, a bifunctional endopeptidase/ sulfhydrogenase found in NADP-reducing hyperthermophiles.The Pyrococcus FrxA is not related to those found in Helicobacter pylori.	1.29889e-22
NC_021658.1|WP_020739198.1|10342205_10344536_+|phosphoenolpyruvate-synthase	gnl|CDD|235809	PRK06464, PRK06464, phosphoenolpyruvate synthase; Validated.	0
NC_021658.1|WP_020739188.1|10334001_10334343_-|hydrogenase-maturation-nickel-metallochaperone-HypA	gnl|CDD|376468	pfam01155, HypA, Hydrogenase/urease nickel incorporation, metallochaperone, hypA. HypA is a metallochaperone that binds nickel to bring it safely to its target. The targets for Hypa are the nickel-containing enzymes [Ni,Fe]-hydrogenase and urease. The nickel coordinates with four nitrogens within the protein. The four conserved cysteines towards the C-terminus bind one zinc moiety probably to stabilize the protein fold.	1.68441e-28
NC_021658.1|WP_020739182.1|10326288_10327656_+|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPA	gnl|CDD|234769	PRK00451, PRK00451, aminomethyl-transferring glycine dehydrogenase subunit GcvPA.	0
NC_021658.1|WP_020739190.1|10334796_10336107_-|nickel-dependent-hydrogenase-large-subunit	gnl|CDD|225798	COG3259, FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion].	1.0843e-86
NC_021658.1|WP_020739185.1|10330260_10331370_-|hydrogenase-formation-protein-HypD	gnl|CDD|237892	PRK15062, PRK15062, hydrogenase isoenzymes formation protein HypD; Provisional.	0
NC_021658.1|WP_148314962.1|10323155_10323278_-|ATP-binding-protein	gnl|CDD|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0.00013918

Protein sequences

>NC_021658.1|WP_044986469.1|10331366_10331621_-|HypC/HybG/HupF-family-hydrogenase-formation-chaperone
MCLGVPGKVLGVTGGDLRLGRVAFAGIVKEICLAYVPEAEAGDYVIVHAGFAISRIDEASARRTLSYLDELDELGAARRGKDPR
>NC_021658.1|WP_020739185.1|10330260_10331370_-|hydrogenase-formation-protein-HypD
MRFIDEYRDAQRVGPYVEAIRRVVSRPWSIMEVCGGQTHAIVRFGLDELLPPEISLLHGPGCPVCVTPIELIDRALEIASRREVTFCSFGDMLRVPGSSDDLFAVKSRGGDVRVVYSPLDALALAERLPDREVVFFAVGFETTAPANAMAVFEARRRGIRNLSLLVSHVLVPPAMEVILRAPDRRVDGFLAAGHVCTVMGIDAYRPLAAEHRVPIVVTGFEPMDILQGIFMCVRQLEEGRAEVENQYARSVREAGNEAAQRMIREVFEIVPRTWRGIGPIARSGLGLRAPYADHDAERRWAPSGDPEPRTLNTCKSGLVLQGIIKPPDCPAFGVRCTPETPLGATMVSAEGACAAYYRYRRADPPCGSR
>NC_021658.1|WP_044989180.1|10329235_10330264_-|hydrogenase-expression/formation-protein-HypE
MSCPVPPRERTVQLAHGGGGRLMRELIERVFLPAFDSGPLLARHDGAVVRLGGASLAFTTDTYVVHPRFFPGGDIGALSVYGTVNDLAMTGARPAYLSAGFIVEEGLPIGELQQIALSMRAAADACGVELVTGDTKVVDRGKGDGLFINTAGIGVVPEGVAIAPRRVRPGDAVLVSGDVGRHGIAVLSVREALSFEEPVESDCAPVAELAAALVESAIDVHCLRDPTRGGLAAVLNEIALDAGVQVEVEEAQIPVEPAVLGACELLGLDPLYVACEGRLVAFLPEAHAERALTSLRDHPLGRGAARIGRVVGEGRGSVVLRTRLGTRRTLDLLSGEQLPRIC
>NC_021658.1|WP_020739183.1|10327652_10329134_+|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPB
MKQTIFDLSRPGVSGAGLRDPDFGELDPSRWFDAESLRTEPIGLPEVSEVELVRHYTALGHRAYGVDDGSYPLGSCTMKYNPKRHDHLANLEGFAHVHPRQPESTLPGLWELLFHLAECFAELTGMDHFTLQPAAGAHGELTGLMIIRAWFESRGVKRDVILIQDSAHGTNPASASMAGYRCEMIRTTPEGLTDLDALEAALDDSVAAVMLTNPSTFGLFERNIREIAERVHANGSLLIYDGANMNSLMGIVRPGDMGFDVLQLNTHKTFSTPHLSGGAGSGPCGVKAFLEPFLPVPVIRRDARGYFPDEDRPRSIGRVKSFYGHVGILIRAYCYILTCGPQGLRTASENAVLNANYVQARLSPYLPPVFGGRCMHECLLSTTKLQVSAFDFAKRLIDHGVHPPTLVGAGCVYFPGHLRDAMLVEPTETETLESLDRMIEKFLRVAREALEDPELVRTAPHTRDVGKILPSGSRDGQPAYSGPTGQPMDSERT
>NC_021658.1|WP_020739182.1|10326288_10327656_+|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPA
MESHPEPLICGYNVHREADRQAMLEALGLTSVAELFSPIPQEVRLGRELRLPPPHSEWALGRHLRELASRNASTRSHLSFLGGGVYEHHIPAVVDSLTSSERLMTAYTPYQPEMSQGLLQILFEYQRMLSLLTGLRIVNSSLYDGATAMAEAAWMACAATGRRRVLASSRIWPEWKSVLELYMRGRGVEVAYVATDPVSGRLDLRSLQESFTRPAATFILQTPNSLGILEDIPAAADVCQQHDALFNVSCYPMILALLKPPGELGADIVTCEGQPLGLPLSAGGPSLGVLACAKRLREFMPGRLVGEVTDIHGQPALALIMEWREQHVSREKATSNICSNQAHQAMRAAIYLAALGERGFRELAAQCAAKARYLHEKLLAIPGVEPAAGGPFFNEFALRLPCPVPLFLERMLDRRVFAGLEMEGNLLVAVTEVRARAELDEAAALFAETIGALRQ
>NC_021658.1|WP_148314195.1|10326048_10326261_+|hypothetical-protein
MLFYLVVLFYLVEGPKRPCAPSSLPRARHMGLGGEHADRGEREITGEPPTFFAVLLRGLAVRGGSPHLRA
>NC_021658.1|WP_020739180.1|10325331_10325481_+|hypothetical-protein
MPPRDRVVMLRFGLDLDDPAHAALFVSDVRAADDAIAAQERWERENALR
>NC_021658.1|WP_020739179.1|10324286_10325099_-|hypothetical-protein
MARRRTGSLFRNDAGRLYVRVLVGDKDRESFPLDPKLTAEQAERHEALVVDVAVRLRASRNVTRDAIVALLERAAVGEGRALRDVIAAADVVCRCRTPTSGAARCASRRTRPAARAPGRCRPACRRRCAPGSRLAATGALRALFVNEDGERVSVEHAAERLRAHVQLVGIGRPQLFEDSGERQQVRAHDTRSTFITVALASGRSESRVADRTGRRSSVVSQRYRRAARTFAELGLGELVSLAEGIDPRARGQGKRRGKRHGGGWGGDSET
>NC_021658.1|WP_148314962.1|10323155_10323278_-|ATP-binding-protein
MTAAGRHNVLLMGTPGSGRAGGPRPMPTIMPRRPSPIVET
>NC_021658.1|WP_148314194.1|10321783_10323052_-|hypothetical-protein
MVPFPRLQALFANFSHTYARICDDDGHGLERRRAEMLLDRAAVMDITGVEKIATDSGSLSKFINLLAELRFALLFAHVGGRVEILPDAAFGIGYYTPDLRVTFPDRLVFLVEVIRGSSGSPDLMEDLDAALKREGIPFRVTDLLGVRLSAAAPDGRTRQENEALCKRVVHEATVGLLAAHSKGLTDGVVHVRAVDSDLRHELRGGRPQRLPLEEDVPCRPGETWVASFVFEPSTLATGYAAGGVTSGHFLDENRQRARFLRDLQNKASKRQKLPPEYASIPYLVAVQNDEHELTTISVLSALTGSRQAFPDSAFEPAKRLQEHPIARPEPVISAARSGWGPVLEAWDYDSNVEVRFTDDGAYLDHRWAKELSGVIVAHGGWLLQWLPNPFATAEINDPRILRIGLPLNKLGTMAPEETGWPF
>NC_021658.1|WP_020739188.1|10334001_10334343_-|hydrogenase-maturation-nickel-metallochaperone-HypA
MHESSIARQLLSAALDRAVAEGATRVLSVRGWVAEAEALSPESLSLHFAAHARGTPAEGARLDLRLLRVEARCLSCGGTYAPDHHVLLCPRCGGDQATLLGRLGLGLDALEVE
>NC_021658.1|WP_020739189.1|10334347_10334800_-|hydrogenase-maturation-protease
MTARIIGLGQRAAGDDAAGLAVLEALRRQGPPGDAELVEARDASALVSLLQTPATVVVVDAVLASPPGEVLDLSPSDLAAGAPVPVSTHGLGVGQAIEIARLAAPDRLSPDIRIVGVSIGRPCRQEPDLSPEVAAAVPRAVARVLSFLGG
>NC_021658.1|WP_020739190.1|10334796_10336107_-|nickel-dependent-hydrogenase-large-subunit
MSASERTRTIAVDYLARVEGEGSLTLVIEDGRAKEARLSIFEPPRFFEAFLRGRGYAEAPDITSRICGICPVAYITSACRAMEDALGIELGPELRALRRLFYCGEWIESHALHVFLLHAPDFLGYPDAVAMARDHRDWVAKGLAIKKAGNAIVALLGGREIHPVNTRVGGFYSAPSRAEIERLLPELRAGREHTRACLSWMATLPCPELERPYEFVALRSDDAYAIAEGRLVSSGGLDIEVRAYDAHFVEEQVSWSTALRSRIRGSGSYLCGPLARFNLSFDRLLPEVQGAARAAGLAVPCRNPFRSLLVRLVEILQAFEESIRIIEAYAPPPAPFVAPPAVRAGTGYGGSEAPRGFLFHRYTLDAEGTILDAKIVPPTSQNQLSIEEDLCALSPSLASMPHREATARAEQAVRNHDPCISCATHFLTLRVEEAPR
>NC_021658.1|WP_020739191.1|10336096_10336873_-|oxidoreductase
MARPAKPKLAVWKFASCDGCQLSVLDLEDELLSLAAAIDIAYFKEATSLERAGPFDLSLVEGSITTPADAERIIEVRRLSKALVTIGACATAGGIQALRNFANVREFLSVVYASPAYIETLATSTAIADHVPVDFELRGCPVNKRQLLEVISAFLHGRRPNVASHSVCVECKMRGNVCVMVTGTPCLGPVTHAGCGALCPTYQRGCYGCFGPMEAPNMESLSRAFRAAGVPERDLVRLHRTFNANAPAFRAESERHER
>NC_021658.1|WP_044989181.1|10336878_10337721_-|Ni/Fe-hydrogenase-subunit-gamma
MAAPSAPSPFAPEPARVRRVHRETATTFTATIEVPGRPGGLAFAPGQFNMLYAFGVGEVAISISGDPARPDRLLHTIREAGSVTRALGSLRAGMALGLRGPFGSPWPVGEARGADVLLLAGGLGMAPLRPALCHILRHRAAYGRVALLYGARGPEDLLYRRELERWSRRADLQVLVTVDRAGPGWRGHVGVVPALLRLADFDPGRAVAFVCGPEVMMRFTARELERRGVPGERVYASLERNMKCAVGLCGRCQLGPSFVCKDGPVLRYDRVGPLLAVREL
>NC_021658.1|WP_020739193.1|10337801_10338278_-|cyclic-nucleotide-binding-domain-containing-protein
MQAQELLPVLGAHPFLEGLPAAHLARLAEGASSRSFPEGAFLLREGGEADTLYLLTQGRVALEIHRPGRDPVQVESLSAGDILGLHWLFPPRRWVLDARAVTQVRAVGLDAAHVRSCSAADPALGYAVSLRLLRQLYARLERVRLQRLDVFNLDGAEP
>NC_021658.1|WP_020739194.1|10338284_10339499_-|4Fe-4S-dicluster-domain-containing-protein
MSGAETGFHPGDRAVLGRPGIAALLQGLREEGYRLIGPTLRGGAIVYDEIQGVEELPAGWTEQQEAGRYRLSRRADEALFGYAVGPRSLKHLLFVPRLRLVQLRRRGGAISRTDEAEAPPRLAVLGARACDLAAIDVQDRVFVDGPHPDPDYVARRRSLFVIAVQCGQAGGTCFCVSMRTGPRAERGFDLALTELLDGGHRFFVEVGSDAGASLLARVGAPRAGEDDARAAFDISRRTATQMGRELETDGIKELFYRNLEHPRWDDVAERCLGCTSCTLACPTCFCSTVEDVTDVAVDDGRDAVDVGRDSAYAGPSAVAERFRRWDSCFSLDHSYLHGGSVRASRRARYRQWLTHKLATWIDQFGTSGCVGCGRCITWCPVGIDITEEAAAIRAGDGAVAAGKG
>NC_021658.1|WP_020739195.1|10339826_10340072_+|ferrous-iron-transport-protein-A
MGPLAQVRAGERAVVVEVGLDADLAGWLGAMGLGPGQTLTLIRRAAFGGPLHVRTGSGGELAISAGLARSILVAPLPSQVP
>NC_021658.1|WP_020739197.1|10340816_10342064_+|ferrous-iron-transporter-B
MLLHPAAGPVLFLGLMALLFAAVFLVATPATEALDAAIGQLGGLVSRALGGGLAASFVVDGLLGGAGTVLAFMPQIVILTVAMELLEASGYLARGAFLVDRLLQLMGLSGRAFLPLLMGHACAVPAVHATRILRDPRERLTAILVLPLMACSARIPTYALLLTTFFAAHGPWVQALLFVALYVAGIFSGLVASLVLRRTATRGRSLPMVLEMPAYRSPEVRVVARKAAQAAWRFTREVGTVILAVSAVLWVLLKVPMPGAAPPEPPAAAAEAAATPLESSIAGGVGRALEPVTAPLGFDWRINVGLIGSFGAREVMVGTMGVIFGVEGADDAPAPLAERIREARRPDGTLAYSTRTGLALLAFFVLACQCMSTVAAIRRETKTWRWPAFVLAYSYAAAYVAALVVYQGSGLLGIR
>NC_021658.1|WP_020739198.1|10342205_10344536_+|phosphoenolpyruvate-synthase
MTAHVLWFDSLSRNDVASAGGKGGNLGELTRAGLPVPPGFVITADAYLAAMEAAGVRKQLCELFDAADPNDPAGLRAACAELRRLVRAAPLSAELQAEIVGAYRELGPGAVVAVRSSATSEDSASTSFAGMHETYTDVTGEQALLGRVRDCWASAFGERVVSYRKSQRLAEEPALAVVVQRMVSSERSGVIFTADPATKDTSRLVVEAAFGLGEVVVGGQVEPDTYTVAKRGPRLVEARVGHKAFKLVRAPDGGGEQRVDLPEDEGARRVLKDDEVLELARLALRVEEHYGAPQDIEWAIEDGATYLVQTRPITTLGAPHPGPGEVLVAGLGASPGTASGAVRVLRAPEEGQRLEAGEVLVAPMTSPDWVPTIRRAAALVTDSGGMTCHAAIVSRELRIPCVVGTRSATRTLRDGELVTVDGAHGKVLEGQRAAAEAPGAAPDGAPAAAGVEPAAKAEARVERAPAAVGTHAAPPAVLGTRLYVNMAIAERAEEVAALPVDGVGLLRAEFMLLDALGGVHPKALIASGGRDEFVERMSAALLRITRAFQPRPVIYRTYDFRTNEFRGLKGGEQFEPAEENPMIGYRGCYRYVRDPELFALELDVLARVRGETPNLHVMIPFVRTRWELAACLDLIDRSPLGRQRGLHRWVMAEVPSAAFWIPEYARMGIDGVSIGSNDLTQLMLGVDRDSALCAELFDESDAAVLDAIGRIIEACRAAGITSSFCGQAPSNRPEFAEHLVRLGITSISVNPDAEPAARKVIAAAERRLLLEAARRP

Crispr_ID: NC_021658_49

• CRISPR_ID: NC_021658_49
• CRISPR_location: 10533993-10534088
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_49

Consensus_repeat	Method
CGGCCCCTGCCAGAGCGCCCAGGG	CRISPRCasFinder

spacers of NC_021658_49

>49.1|10534017|48|NC_021658|CRISPRCasFinder
GAAGCGCCGGCCGCCGCCGTCGCGGAGATCGCGGGGGGTCGCGGCCGG

CRISPR arrays and Neighbor proteins around NC_021658_49

CRISPR arrays

The CRISPR arrays of NC_021658_49

>merge|NC_021658|49|10533993-10534088|CRISPRCasFinder
CGGCCCCTGCCAGAGCGCCCAGGGGAAGCGCCGGCCGCCGCCGTCGCGGAGATCGCGGGGGGTCGCGGCCGGCGGGCCCTGCCAGAGCGCCCAGGG

>NC_021658|49|43|10533993-10534088|CRISPRCasFinder
CGGCCCCTGCCAGAGCGCCCAGGG	GAAGCGCCGGCCGCCGCCGTCGCGGAGATCGCGGGGGGTCGCGGCCGG
CGGGCCCTGCCAGAGCGCCCAGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_148314967.1|10530532_10531645_+|DUF882-domain-containing-protein	unknown	unknown	gnl|CDD|225650
NC_021658.1|WP_020739335.1|10522204_10523542_-|hypothetical-protein	unknown	unknown	gnl|CDD|274360
NC_021658.1|WP_044986493.1|10524739_10527115_-|type-IV-pilus-secretin-PilQ	unknown	unknown	gnl|CDD|274173
NC_021658.1|WP_020739352.1|10545344_10546346_-|folate-binding-protein-YgfZ	unknown	unknown	gnl|CDD|223431
NC_021658.1|WP_020739346.1|10537907_10538708_+|phosphatidate-cytidylyltransferase	unknown	unknown	gnl|CDD|366491
NC_021658.1|WP_044986497.1|10540274_10541369_-|tryptophan--tRNA-ligase	unknown	unknown	gnl|CDD|183400
NC_021658.1|WP_020739353.1|10546422_10546974_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739354.1|10547084_10547663_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739338.1|10527203_10527845_-|hypothetical-protein	unknown	unknown	gnl|CDD|377322
NC_021658.1|WP_080682492.1|10538873_10540199_+|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl|CDD|223411
NC_021658.1|WP_044986498.1|10541520_10543254_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_021658.1|WP_049949742.1|10535608_10536991_-|3-keto-5-aminohexanoate-cleavage-protein	unknown	unknown	gnl|CDD|377562
NC_021658.1|WP_020739341.1|10529120_10530182_-|type-IV-pilus-assembly-protein-PilM	unknown	unknown	gnl|CDD|378558
NC_021658.1|WP_020739345.1|10537049_10537883_+|di-trans,poly-cis-decaprenylcistransferase	unknown	unknown	gnl|CDD|259850
NC_021658.1|WP_148314968.1|10531770_10532748_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274153
NC_021658.1|WP_020739351.1|10543307_10545263_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_021658.1|WP_020739340.1|10528479_10529124_-|PilN-domain-containing-protein	unknown	unknown	gnl|CDD|225707
NC_021658.1|WP_020739334.1|10520363_10522193_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223717
NC_021658.1|WP_020739336.1|10523742_10524681_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176109
NC_021658.1|WP_020739339.1|10527841_10528480_-|type-4a-pilus-biogenesis-protein-PilO	unknown	unknown	gnl|CDD|309474

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_148314967.1|10530532_10531645_+|DUF882-domain-containing-protein	gnl|CDD|225650	COG3108, COG3108, Uncharacterized protein conserved in bacteria [Function unknown].	1.47195e-16
NC_021658.1|WP_020739335.1|10522204_10523542_-|hypothetical-protein	gnl|CDD|274360	TIGR02946, Putative_diacyglycerol_O-acyltransferase_Mb3115, acyltransferase, WS/DGAT/MGAT. This bacteria-specific protein family includes a characterized, homodimeric, broad specificity acyltransferase from Acinetobacter sp. strain ADP1, active as wax ester synthase, as acyl coenzyme A:diacylglycerol acyltransferase, and as acyl-CoA:monoacylglycerol acyltransferase. [Unknown function, Enzymes of unknown specificity].	1.26846e-15
NC_021658.1|WP_044986493.1|10524739_10527115_-|type-IV-pilus-secretin-PilQ	gnl|CDD|274173	TIGR02515, Putative_DNA_transport_protein_HofQ, type IV pilus secretin (or competence protein) PilQ. A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. [Cell envelope, Surface structures].	4.39145e-146
NC_021658.1|WP_020739352.1|10545344_10546346_-|folate-binding-protein-YgfZ	gnl|CDD|223431	COG0354, COG0354, Predicted aminomethyltransferase related to GcvT [General function prediction only].	1.24077e-28
NC_021658.1|WP_020739346.1|10537907_10538708_+|phosphatidate-cytidylyltransferase	gnl|CDD|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	1.19833e-45
NC_021658.1|WP_044986497.1|10540274_10541369_-|tryptophan--tRNA-ligase	gnl|CDD|183400	PRK12282, PRK12282, tryptophanyl-tRNA synthetase II; Reviewed.	1.90534e-131
NC_021658.1|WP_020739338.1|10527203_10527845_-|hypothetical-protein	gnl|CDD|377322	pfam04351, PilP, Pilus assembly protein, PilP. The PilP family are periplasmic proteins involved in the biogenesis of type IV pili.	1.08387e-06
NC_021658.1|WP_080682492.1|10538873_10540199_+|Glu/Leu/Phe/Val-dehydrogenase	gnl|CDD|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	7.06691e-166
NC_021658.1|WP_044986498.1|10541520_10543254_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.80358e-161
NC_021658.1|WP_049949742.1|10535608_10536991_-|3-keto-5-aminohexanoate-cleavage-protein	gnl|CDD|377562	pfam05853, BKACE, beta-keto acid cleavage enzyme. BKACE, beta-keto acid cleavage enzyme plays, a role in lysine degradation. In certain instances it catalyzes the conversion of 3-keto-5-aminohexanoate and acetyl-CoA into acetoacetate and 3-aminobutyryl-CoA. The family is found to have at least 14 slightly different potential new enzymatic activities, all of which can therefore be designated as beta-keto acid cleavage enzymes.	1.37469e-117
NC_021658.1|WP_020739341.1|10529120_10530182_-|type-IV-pilus-assembly-protein-PilM	gnl|CDD|378558	pfam11104, PilM_2, Type IV pilus assembly protein PilM;. The type IV pilus assembly protein PilM is required for competency and pilus biogenesis. It binds to PilN and ATP.	1.66552e-71
NC_021658.1|WP_020739345.1|10537049_10537883_+|di-trans,poly-cis-decaprenylcistransferase	gnl|CDD|259850	cd00475, Cis_IPPS, Cis (Z)-Isoprenyl Diphosphate Synthases. Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.	1.80683e-111
NC_021658.1|WP_148314968.1|10531770_10532748_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274153	TIGR02479, RNA_polymerase_sigma_factor_WhiG, RNA polymerase sigma factor, FliA/WhiG family. Most members of this family are the flagellar operon sigma factor FliA, controlling transcription of bacterial flagellar genes by RNA polymerase. An exception is the sigma factor WhiG in the genus Streptomyces, involved in the production of sporulating aerial mycelium.	1.68954e-51
NC_021658.1|WP_020739351.1|10543307_10545263_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	7.82993e-171
NC_021658.1|WP_020739340.1|10528479_10529124_-|PilN-domain-containing-protein	gnl|CDD|225707	COG3166, PilN, Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion].	8.40812e-07
NC_021658.1|WP_020739334.1|10520363_10522193_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	8.41486e-21
NC_021658.1|WP_020739336.1|10523742_10524681_+|LysR-family-transcriptional-regulator	gnl|CDD|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.24253e-56
NC_021658.1|WP_020739339.1|10527841_10528480_-|type-4a-pilus-biogenesis-protein-PilO	gnl|CDD|309474	pfam04350, PilO, Pilus assembly protein, PilO. PilO proteins are involved in the assembly of pilin. However, the precise function of this family of proteins is not known.	1.11758e-27

Protein sequences

>NC_021658.1|WP_148314968.1|10531770_10532748_+|sigma-70-family-RNA-polymerase-sigma-factor
MQREEFAPPRPLLPCCDAEEFVQPVILGETCPVVTCDRALIEAPGALGLDALDDAPDALVQEPGAALALEAWEPAEVTSGCAHDAWDSGEAPSPCTSEEGWQAAEPDTHAGCPPCCTEAACASGPQRRELPCAPLRAEVLKGYFPLVRKLVRQVSRHLPPNVQRDDLLSAGMLGLVDSLRKNGGSDGETFAGYAKLRIRGAIVDELRAQDWLSRRAREAVEAGAAGKVGGTTVFVSLSEVTPAEESVHMAGGDDPIEAISAQATRRALSFAIAQLPERERRVIGMYYFEGAKLKDIGAELGVGEPRVSQLHTRALGMLRGMLSHA
>NC_021658.1|WP_148314967.1|10530532_10531645_+|DUF882-domain-containing-protein
MEPRPRSSRLRSVLAALAAALLLSAAPGEALAEDGQHTVYAGQTLGKIAKRYRITVDALREANGLKPGQRIHPGLVLVIPERGKPGARPPRGAPGRAAALRDEPERSRGASAKERAAEARGKGPSKRDAKADPRSLPPSKRYVQRPKRPGWVRLVRGAERLELRLLTPKGRLVPKSLPKLSRLMRASPTASVPIDPRLATLIGMVSDHFGGRTIRVVSGYRPYSPTQYTPHSNHNFGRAIDFMVEGVPNTVVRDFCRGFRNAGVGYYPNSTFVHLDVRSDKVYWVDYSGPGEPPRYEGARGAVAADEAARDVPVSAEEEVYGSGEPRPTQPQGSNTTGTNSDAGRGGGEPQRGVGAGAPSPAPAASAAGK
>NC_021658.1|WP_020739341.1|10529120_10530182_-|type-IV-pilus-assembly-protein-PilM
MSEGKNLVGVDIGSSAIKIAQIKEGRKGYGLVRLGYAPLAPQAIVDGHVMNAQAIVEALGRAFSEARIRQREIALSISGQAVIIRKITVPLMTAAELDEQIQWEAEQHIPFDIKDVHVDYEVLRRRPEAGQMDLLLVAAKRDEINDYTQIARNAKLKPMVVDIDAFTVQNLFEVNRGIPPDQTFAIINVGASLASINIVSRGASAFTRDIGNGGNYITEQIQRKLGISFEQAEEFKCASVTSGPGGVPAQVIETIEQVCDSIAGEIQRSLDFFLATSGEGDMHRIYLTGGSSNLPALPAAIGRRARVAVELIQPMERITVEAKEVNQELLRLRAAQFCVSLGLAMRKDREKRS
>NC_021658.1|WP_020739340.1|10528479_10529124_-|PilN-domain-containing-protein
MIRVNLLPQRRGTRGAAPQASQRWLLVTLGVVILEIVALFLFHQTKVEELDEQTRKNTVLQSQIQEIRTLVANHEEIKKALEVLRAREDAIAKLQAARSGPTAVLLELAQLLTNGKGPTADPDKLAQLRKENPLAVYNPSWDSRRLWLSSYVESERTVRIEGLARDGTDVYELAQRLKLSSYFYDVQLLPGKKENEKASRLELVSFALQLKVRY
>NC_021658.1|WP_020739339.1|10527841_10528480_-|type-4a-pilus-biogenesis-protein-PilO
MATKPQPVQAGSALDRLPPLAKVGVGALFAALVGILYFVGFYAEVDSQIEGAVQRQQSLQAELTKAQASKAAYQKDLDEKTRREQLSREQKKILPDESETPAFLSAIQGVATVSGVNLTSWSPTEEIPQEFFSKVPMKLTLSGKFHQVAKFFHGVGQLDRIINLEEVQIKEPKVVGTDVEVEVECLATAFRAVRAGETSTSGVKRRGGGGVR
>NC_021658.1|WP_020739338.1|10527203_10527845_-|hypothetical-protein
MNAGRMMLIALGATALAAVSLAGCEDEPDVITSAPKARPPSSASPARAGAPAAASADAGAPELPPLPLREFQEADFSESDRSRDPFRSFESLFATQARGRVTIQRQVLVDRFALDELKLVGVVSRAPARALLTDPTGLGWVVKVGDFVGKAEIVHAGGPTGVDVAVNWRVDRIRDSDVVFIREDPSHPEIPPTTRVIALRPLGDADESAFGSP
>NC_021658.1|WP_044986493.1|10524739_10527115_-|type-IV-pilus-secretin-PilQ
MKSNRDYRPRRGALRRAAALGMMLILAPAGDADAAAPIRVSDVRLTAPSEDRAEIVVATSGAPRFSARVADGGKRILVDLEGAEAAGAPGAITDGNAIVAGVMTQGFGAAAQRTTRVLVQLARPAAYRIRAEQGALVIELAAADATAPMTARAPASREAAAPAREPATITDVRFEHQATVDRVIIELSSIPSYRESTGRAGRRVIELSGARLPDALQRKLDVGAFGGPVRAISAFRRNSDGSKVVVEVEQAEGAAGALAREGNALVLSVAKGALPSTLSGIGADGGAARRTRTVAREDLLGDAAPRVETSFEGADGGVGAEPGFAGRSPHHQESSQESLVEPDQAGAFTPALAGQQRRFTGRRIDLDLKDADIHNVLRLISDVGRVNIVTADNVSGTVTIRMRNVPWDQALETVLQAKGLGVVRQGNMIRVAPIADLNKERELAIARRKSELQLAPIETRLIPINYADAKDLQDRAKDMLSPRGSLAVDERTNVLIARDVAGNLNQIEELVRSLDTQTPQVLIEARVVEATSRYVRDIGIQWGGDGTFSAATGNPTGLVFPSAIGLAGGATDTNTPTGGLSPFSNTVSNPNFAVNLPAVVGAGQGGALGFTLGSINNTVNLGVRLSAAEASGMLRIISSPRILTLDNREARISQGTLIPFSQISAQGVQTTFQEAKLQLLVKPHVTSDGSVAMHVKINRDEPDFNQTSARGDPTILKREAETDLLIMDGHTAVIGGIFTRNTGRNLDQVPFFGDIPVLGLLFQRRRASDTRSELVIFLTPRIVNRAEALGR
>NC_021658.1|WP_020739336.1|10523742_10524681_+|LysR-family-transcriptional-regulator
MNLSAIDVNLVIALDALLQERSVTHAARRVGLSQPAMSHALTRLRELFSDPLLVRVGRQMALTSRAEAMTPQVAALMHDLASLFGGARPAFEPRASERTFRIATTAYVELLLLPQLNEVLAESGPKLALHLLPLDARAVDALRNGEIDLAIGAFPEGALPPDVRRAALFDDRFTGLARSSHPSARGRVDLQAYAALGHAVVPRQAAHDGGADDLIAARGVARREVIAVPHVFLLPHVVTSSDLVATVATRLGRAFSSLMPLRTFDLPFELPPIEIAMAWNGRTEDEPARAWLRGVVTAAVPQMREATRRKRI
>NC_021658.1|WP_020739335.1|10522204_10523542_-|hypothetical-protein
MTSTVLLGGIDHFHLMNDRAMRARGQAGNHCLFVLELDGRLDLGRLAARLERATRALPELRFRLDNSVLGRVGRPRWVVDHHRRAPEPRLHEVAGERERAARIEALLAERISGERPWALDVVRGAGEGDTVVLRHHHALTDGRGADRLVAWLGSGSGDAPDDPPLRQERHDAPERLLGAMGRDERLALARAYKAHVLALGRAPILSLARACPGVRAATSRVARLALSAEETRAFDLRVRQRARLAETSLMLIAAARLADRALVARGFAPPHHVVPLPLSLDPKGGARRLFGNHLTMVLLSLGRDELYDDARAVARVAEQQRAMVRDRLDLAMVAALDLARWLPGPVYRWLGDQPFEGELASLIVSNPGAVTVDRFAGLPVRSAHPLPAVVTPPGFQVIFSRFGGRLSASIVYGDGLLRPDEAAAMPGALRAELLGEPAAPAGGGV
>NC_021658.1|WP_020739334.1|10520363_10522193_-|NAD(P)/FAD-dependent-oxidoreductase
MRTFDIVIIGSGIAGGFLARQLRLARPDLGVLVLEAAGAMEDYKVGESTVEVAANYMVRRLNLGTYLYQHQLPKNGLRFFFDGPGKDLPLPRMSEIGSDHMPFHPSFQLERARLERDLVAMNRAAGAEVELGAKVVDLAIDGGGRHKVVYEQGGERREVACRWVCDASGRRHVLLRKLGVKVHKETRLNTAAAWGRYRGVAGLDAVTDAAWRSRARYTSRHLSTNHFMYDGYWIWFIPLAGDLMSVGVVFDKDRIGEGNAPAGALPGPRTRADFERFLGAHRAVRELLEGAELEDFQAYAHLPYHADRYFSTDRYAVTGEAGAFTDPFYSPGSDFIATANEFITQMILADVGGDRAGFEERVAAYDAYYRFKYDSTLRLYERMYPVFGSFELYRLKYLLDFNNYYNLVVWPFMADRVTDVGWIREELRFTDLVLRALSTMGDHFASLAADLRARGEYFAQNEGRFANGLNGVVQLETRLGPSIDERFRREQVDRAYGSVFAALVERRLAERGLSDRARLVSELKLPQVLTFRDITPDRLARLLDRIGERMTKDLRAEFPDAGVERVELGSGGEVSVTGPAVGTEVHAAVLSRARSLWDASAGSLAHVAL
>NC_021658.1|WP_049949742.1|10535608_10536991_-|3-keto-5-aminohexanoate-cleavage-protein
MSTGVGLTITLRVRMGAHDAHYAGELCDGARILALFGDVATELLIRLDGDEGLFRAYEAVEFLAPVRAGDFIEATGVVTKVGATSRTMAFEARKVVASVREPGVAPSAADALAEPVIVCRALGTCVVPKELQRRPRLVLPALSAPPPDHAQLPEPRPIITPPPRIIVTPPDSALILTAAIVGAETTRAQTPHLPVTARELADEAARCRDAGAAVVHLHVRNPDGTPSQSRALFADAIAAIQEKTDVIVQTSTGGAVGMGVDERAQPLLCRPEMATLNCGTLNFGDGIFDNARPLIRDMAARIREAGSIPELECYEVGHIHEALSLLAEGLLAEPLHFQFVLGVPGGIAAREDVLRFMISQIPRGSSWGVAAVGRHQRPMTELAMQLGGHARVGLEDNIYLEKGVLAEGSAPLVARAAAFARSVGREVVDPDRARQLLGIRPRAAAAQAGAAGGGSALAQG
>NC_021658.1|WP_020739345.1|10537049_10537883_+|di-trans,poly-cis-decaprenylcistransferase
MNLVEARNLPRHVGIIMDGNGRWAELRGEPREAGHKAGSAAVRRIVRVCRRLGVEALTLYAFSEQNWARPRNEVDALMGLLREFLMSERCEILENDIRLVAIGDISRLPEPVRDVLDPLRKASATNRQMTLALALSYGAREEIAAAARELAMEAVAGRLDPEAIDGALLAARLPSLSVGEPDLIIRTGGEQRLSNFLLYGAAYAELSFTERLWPDFTEDDLFDAIAAYQQRVRAAEPADEAEGGGADEPARASGALGAGRPWRAREVASHNGSRTGV
>NC_021658.1|WP_020739346.1|10537907_10538708_+|phosphatidate-cytidylyltransferase
MRVLTAIVAAPILLSLLYLGPSWGWAALVAVASAIGALEFFAMTHADDRAARVAGVALTLGVLGVLWRFGGSPAALLALIFLLPFVAMLVTLVRLGDMRTAALRVLAMTFGPLYVGGGLGALALLRRDAGADGPSFVVLALLLSWFSDTGAYFAGRFLGRRKLYEAVSPKKTVEGALGGLVFAVLGALLAHFWFLRSLPLVDGIALAIVAGGLGQAGDLGESLFKRSFGIKDSGGIVPGHGGILDRVDALLVTGTITYLYVLWSRS
>NC_021658.1|WP_080682492.1|10538873_10540199_+|Glu/Leu/Phe/Val-dehydrogenase
MEDQVSTKNTTPPVSGAAAPGHKHKYEFFKVVQGYLDEAARLIELPGYITTILSQPKNEIIVNFPVRMDDGSIRLFKGYRIQHNNLLGPFKGGIRYHETVSLDDLKALAAMMTWKCALMNLPLGGGKGGIKFNPNEVSRAELQRITRRFFHALGSNIGPETDIPAPDVGTDAKTMAWAMDTYMNTVGQLFKQAVKGVVTGKPVASGGTYGREKATGQGVVHCITEWAEDNDVNLGGATLLVQGFGNVGSNTAVLLSKLGASTVAVGDHTGYLYNPEGFNPHKLQDYVKKHRSIAGYPAGKPISREEFFRLKADIFIPAALENQVGVEEASWLQVRLVAEGANGPCTPEGERVLLERGTDILPDVLANSGGVTVSYYEWVQNKRSETWTLEEVDARLEKAMKRAYREVTEMARQKKCTLRLAAYAVALQRLAAVYGEREIFP
>NC_021658.1|WP_044986497.1|10540274_10541369_-|tryptophan--tRNA-ligase
MSSSTSSPSAQPGRPRILTGDTPTGRLHVGHWVGSIENRVRLQDSYECYFLIANVHAFTTRADRPDDIRRDMLEIVKDWLAAGIDPERSTLVLQSEVPAIAELTWFFAMQLPFNRVMRNPTLKHEIETKGLGDKYSFGFPLYAVGQCADILAFRPALVPVGEDQVAHLEMCREVARRFNHVYCDVDPALDDEAHVTAGGLFPIPAPLVGRVGRLVGTDGVHKMSKSLNNAIFLSDSAKEIKKKVGALYTGRQSMTDPGDITSSLFQYVRAFIKDPARVQVLEERYSRGDNIGDGHIKAEITAAIDELLGPMRARRAEYDRPGGDDLVLDILREHAARANAVAEETLYLAKQRMKMDIGRRTLGL
>NC_021658.1|WP_044986498.1|10541520_10543254_+|ABC-transporter-ATP-binding-protein
MLRQLLRRFLRPQAPLLAIVVALQLVATLASLYLPSLNADIIDHGIAAGDTSRILELGAIMLAITGVQIVCSVAANYAGARAAMSFGRDLRAAVFHRVGEFSARELSRFGAPSLITRTTNDVQQVQMVVMMGCTMLVLSPIMCVGGVVMALREDRSLAWLLAIAVPLLAGAVVAIMSRMVPQFRRMQPLIDAVNRVLREQITGVRVIRAFVRERAEAARFDRANGDLTEAALHIGRLQAMMFPTVMFVFNASSVAVLWFGAHQIADGRLAIGSMTAFLAYLTQILMAVMMVTFMAVMLPRAAACSERILEVLDAEPSVRAPDQPVTLVEPAGVVELRDVEYRYPGAELPVLRGISFVARPGQVTAIIGSTGSGKTTLLDLIARLIDPTRGEVRLDGVDARMLALEAVWSCIGLVPQRPFLFSGTVASNLRYGDPAATDEQLWAALAAAQARDFVEAMPQELDTPIGQGGTNVSGGQRQRLSIARALLRRPRVFLFDDAFSALDVATEARLRAALAERTGAATVIVVAQRVSSIVDADQILVLDGGELVGQGKHGELLASCPTYAEIVASQREAAAAA
>NC_021658.1|WP_020739351.1|10543307_10545263_+|ABC-transporter-ATP-binding-protein
MLQRGPFGMGAAPPQKAKRFAPSARRLLGRLAPERARLAVVIACSLLSVGLGLAGPKLLGRATDIIFSGVIGARLPAAATKAEAVAELQRSGQARLAELVGHMDVVPGRGIQLRELAELLLLVMALYAGASLFAWLQGYLLNEVVQRAVRQLRTDAQDKLARLPLAYFDGRPHGELLSRVTNDIDNIAQGLQQTLTQIMNGALTLVGIVVMLVVISPVLAVITLFTVPLSVLTTAAVAKRAQAKFVAQWAQVGALNGQIEEAFTGHSLVNVLGRRRDVEARFQSTNQELFEASFRAQFMSSTIMPAVNFVGNLTYVAIAVVGGLRVASGAMLLGSVQAFIHYSRQFSQQLGQLASVTNVLQSGVASAERVFELLDEQGQSPEAAPPAALPKVVGEVRFEHVTFRYKPDEPLIEDLDLTIMPGQTVAIVGPTGAGKTTLVNLLMRFYELDGGRILIDGVDIARLPRHELRAKLGMVLQDTWLFSGTIRDNIAFGDAAATEADIQEAARAAHVDRFVRALPAGYDTVIDEASGNLSAGEKQLITIARAFLARPAILILDEATSSVDTRTEVLVQRAMAALRAQRTSFVIAHRLSTIRDADVILVMNAGRIVERGAHAELLAAGGAYHALYKTQLTGSGGSGATLEGQRAAPSA
>NC_021658.1|WP_020739352.1|10545344_10546346_-|folate-binding-protein-YgfZ
MNDAHGLDEQRRALREGALVQPMPELGTLIVTGSDRQTWLNGLVTCDLAPQKPLPAGAKAAPPAGGAYGLNVVKTGKIFAEVWIVIAEDRIYVGALRDRIEALRESFDRYLIMEDAELADATGEHAWVFAHGPRAADLAAAGRAAGADAAIVDWTGLGGALFVAPRQAEGAVLEALRAAGEAGPVLPTTAAAWEVLRVENNVPRFGVDFDDQNFPQEASLEERAVSFNKGCYLGQETVFMLQMRGHAKKRLVQLAVEGEDAVPAGAEIALPDGAAVGAVTSQVKDPGGPRVLALGYVKYKHAAQGTALRVAGRAAEITRAPGAAAASGAAPGR
>NC_021658.1|WP_020739353.1|10546422_10546974_-|hypothetical-protein
MALVGLVGSESPAEDAARLHELNISALAFAEAGPAMQGAARATKTVPSLCLSRVSDRDGALAARYHGADGVCIDALLPLDEWDRLAKGARTMRMLPLALAESPEGAEAAAKVGARAVLVRGASADAVIASVASLPKTLTVVAEVLSADADALRRLVGHVDAAIVPPSVHTSPQFPALVAEVDP
>NC_021658.1|WP_020739354.1|10547084_10547663_-|hypothetical-protein
MTTSAPGAASGAPLPVKLGPFDAEFLADLPYDPSVLFFDELLEVDAERSLVRCRMPTDRPMPLVDAQRAHPLLHPRHVAGAIMVHATGMLGFVHAYHLLGLRHREGWIGYGTNIHRVVFRKLVQPGAPIEATCVATRSRLGQKRHMIRYSFEFRHEGSVCYEGDQTAVWMRVQDVPAMDSRPALEELERSLA

Crispr_ID: NC_021658_50

• CRISPR_ID: NC_021658_50
• CRISPR_location: 10765963-10766259
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NC_021658_50

Consensus_repeat	Method
GCCGCCTTCTCCGGCNCN	CRT

spacers of NC_021658_50

>50.1|10765981|30|NC_021658|CRT
CCGCCGGCTGACTTCTCTGGAACAGCGCGC
>50.2|10766029|18|NC_021658|CRT
GCGCCCGTCGACTTTTCC
>50.3|10766065|33|NC_021658|CRT
GCAGCGCCCGCCGCCTTCTCCGACCCAGCGCCC
>50.4|10766116|30|NC_021658|CRT
CCGCCCGCCGCCTTCTCCGACACCGCGCCC
>50.5|10766164|30|NC_021658|CRT
GCGCCCGCGGCCTTCTCCGACACCGCGCTC
>50.6|10766212|30|NC_021658|CRT
GCGCTCGCCACCGCCGCCGGCGCGGCGCTC

CRISPR arrays and Neighbor proteins around NC_021658_50

CRISPR arrays

The CRISPR arrays of NC_021658_50

>merge|NC_021658|50|10765963-10766259|CRT
GCCGCCTTCTCCGGCGCGCCGCCGGCTGACTTCTCTGGAACAGCGCGCGCCGTCTTCTCCGGCGCGGCGCCCGTCGACTTTTCCGCCGCCTTCTCCGGTCCAGCAGCGCCCGCCGCCTTCTCCGACCCAGCGCCCGCCGCCTTCTCCGGCGCGCCGCCCGCCGCCTTCTCCGACACCGCGCCCGCCGTCTTCTCCGACGCCGCGCCCGCGGCCTTCTCCGACACCGCGCTCGCCGCCTTCTCCAGCACCGCGCTCGCCACCGCCGCCGGCGCGGCGCTCGCCGCCTTCTCCGCCACC

>NC_021658|50|9|10765963-10766259|CRT
GCCGCCTTCTCCGGCGCG	CCGCCGGCTGACTTCTCTGGAACAGCGCGC
GCCGTCTTCTCCGGCGCG	GCGCCCGTCGACTTTTCC
GCCGCCTTCTCCGGTCCA	GCAGCGCCCGCCGCCTTCTCCGACCCAGCGCCC
GCCGCCTTCTCCGGCGCG	CCGCCCGCCGCCTTCTCCGACACCGCGCCC
GCCGTCTTCTCCGACGCC	GCGCCCGCGGCCTTCTCCGACACCGCGCTC
GCCGCCTTCTCCAGCACC	GCGCTCGCCACCGCCGCCGGCGCGGCGCTC
GCCGCCTTCTCCGCCACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_148314974.1|10760383_10760680_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949748.1|10754770_10755703_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|380379
NC_021658.1|WP_148314245.1|10778828_10779986_-|uroporphyrinogen-III-synthase	unknown	unknown	gnl|CDD|119440
NC_021658.1|WP_148314975.1|10762093_10764859_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_063752065.1|10772107_10773049_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_021658.1|WP_020739502.1|10760868_10761336_-|hypothetical-protein	unknown	unknown	gnl|CDD|185628
NC_021658.1|WP_148314244.1|10778022_10778841_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739497.1|10756938_10757955_+|isocitrate/isopropylmalate-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223549
NC_021658.1|WP_020739507.1|10769444_10769894_+|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl|CDD|235383
NC_021658.1|WP_020739499.1|10758864_10759608_-|hypothetical-protein	unknown	unknown	gnl|CDD|366517
NC_021658.1|WP_148314976.1|10771001_10772000_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl|CDD|273137
NC_021658.1|WP_044986538.1|10755788_10756670_-|OmpA-family-protein	unknown	unknown	gnl|CDD|224279
NC_021658.1|WP_020739505.1|10768219_10768975_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739511.1|10773156_10774602_-|protease-TldD	unknown	unknown	gnl|CDD|182685
NC_021658.1|WP_020739508.1|10769964_10770945_+|hypothetical-protein	unknown	unknown	gnl|CDD|224805
NC_021658.1|WP_020739512.1|10775167_10777924_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NC_021658.1|WP_020739500.1|10759604_10760120_-|Smr/MutS-family-protein	unknown	unknown	gnl|CDD|225396
NC_021658.1|WP_020739498.1|10757980_10758817_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739506.1|10768971_10769442_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_063752064.1|10765385_10765934_-|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239516

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_049949748.1|10754770_10755703_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|380379	cd06124, cupin_NimR-like_N, AraC/XylS family transcriptional regulators similar to NimR, N-terminal cupin domain. This family contains mostly bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included in this family is Escherichia coli HTH-type transcriptional regulator NimR (also called YeaM) that negatively regulates expression of the nimT operon and its own expression. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	2.43152e-22
NC_021658.1|WP_148314245.1|10778828_10779986_-|uroporphyrinogen-III-synthase	gnl|CDD|119440	cd06578, HemD, Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in the human uroporphyrinogen-III synthase gene cause congenital erythropoietic porphyria, a recessive inborn error of metabolism also known as Gunther disease.	7.78621e-34
NC_021658.1|WP_063752065.1|10772107_10773049_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	9.88448e-34
NC_021658.1|WP_020739502.1|10760868_10761336_-|hypothetical-protein	gnl|CDD|185628	PTZ00449, PTZ00449, 104 kDa microneme/rhoptry antigen; Provisional.	0.00221947
NC_021658.1|WP_020739497.1|10756938_10757955_+|isocitrate/isopropylmalate-dehydrogenase-family-protein	gnl|CDD|223549	COG0473, LeuB, Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism].	6.004e-152
NC_021658.1|WP_020739507.1|10769444_10769894_+|D-tyrosyl-tRNA(Tyr)-deacylase	gnl|CDD|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	1.02036e-79
NC_021658.1|WP_020739499.1|10758864_10759608_-|hypothetical-protein	gnl|CDD|366517	pfam01213, CAP_N, Adenylate cyclase associated (CAP) N terminal.	0.000225147
NC_021658.1|WP_148314976.1|10771001_10772000_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl|CDD|273137	TIGR00557, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase. This model represents PdxA, an NAD+-dependent 4-hydroxythreonine 4-phosphate dehydrogenase (EC 1.1.1.262) active in pyridoxal phosphate biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	4.38983e-103
NC_021658.1|WP_044986538.1|10755788_10756670_-|OmpA-family-protein	gnl|CDD|224279	COG1360, MotB, Flagellar motor protein [Cell motility and secretion].	1.33602e-27
NC_021658.1|WP_020739511.1|10773156_10774602_-|protease-TldD	gnl|CDD|182685	PRK10735, tldD, protease TldD; Provisional.	5.09237e-154
NC_021658.1|WP_020739508.1|10769964_10770945_+|hypothetical-protein	gnl|CDD|224805	COG1893, ApbA, Ketopantoate reductase [Coenzyme metabolism].	1.04781e-14
NC_021658.1|WP_020739512.1|10775167_10777924_+|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	2.16726e-14
NC_021658.1|WP_020739500.1|10759604_10760120_-|Smr/MutS-family-protein	gnl|CDD|225396	COG2840, COG2840, Uncharacterized protein conserved in bacteria [Function unknown].	8.13714e-24
NC_021658.1|WP_148314975.1|10762093_10764859_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.06358e-85
NC_021658.1|WP_063752064.1|10765385_10765934_-|NUDIX-hydrolase	gnl|CDD|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	4.92253e-41

Protein sequences

>NC_021658.1|WP_063752064.1|10765385_10765934_-|NUDIX-hydrolase
MGITIPRRHASAVAGTFGPLAVHRHEVVAAGAPYPVFTIELADWISVAAVTDAGEFVLVRQFRYGVDAVTIETAGGIVDPGEEPAAAALRELLEETGYAAASIESLGWVHPNPALQANRCSLYLARGARRVGEPEGDEHESTEPVVMSADEVTAAMQDGRISHVIAVVTLLRALAAANPSPR
>NC_021658.1|WP_148314975.1|10762093_10764859_+|protein-kinase
MPQGETFEAGCAAAGAREREVRATTAVVAPPPSLRLQTKPPPSAGTSIGHYELLRELGQGGMGVVFLARDTRLARLVAIKLLTRLSSLGVQRFLVEAQATARCKHEHIVTIYEVNEHDGYPYMVLEYIEGQSLRGWMEQRRPAGAGEEASTAPLPPGLAVDMMVPVVRALASAHASGIVHRDLKPENIVLDASGAIKVVDFGIARLRDDEASLAAEGSFAGDARLTPDGGMIGTLPYMSPEQWRGVEIDPSSDIWAVGIILHELVLGAHPLAPYDRMVLLRVPALDEPMPEVGARHPELGALGAIIDRCLRKRKAERYASAEELLAELLPLLPGRGEIHLDADESPFAGLSSFQEADADRFFGRAQDLAGVVARLRSQPLLAIAGASGVGKSSLVRAGVIPALKRSGEGWEALVLRPGREPLAALAELFTSPAVTLSAELRALVPEGGAEARAALAPRLRAEPGLLGAALRGWAARAQKRLVVFVDQFEELFTLGAPADERAAFLACLEGIADDASSPLRVVLSVRSDFIERLAGHERFMAAMLRGLVFLRPMGREGLREALVRPIEAARHEIEDPAMVEGILDALEATHGALPLLQFTAARLWEMRDRKRRLLTRASYEALGGVAGALASHADTLLAGMSGRQAKLARAVLERLVTPERTCAVASLGELCELPGDPVAIERVVGLLADGRLLAIERGSDRAGGTVEIVHESLIERWPTLKRWLDESEEDAVFLDRLRAAARLWDSSHRAADMLWRGKVAEEARGFRRRYRREMPERERLFLEEVLRLADDKQRRRRRLVTGVIAALLLLMVSGTGFVKATHQNWLIMGQNEDMWRAIASAAEARSAADKARRESEAQLVLAELMLRDAVEDRERAEVEAERAQLAAIEARKAEVKARKVVEEAARRRRMRSGPYEIATER
>NC_021658.1|WP_020739502.1|10760868_10761336_-|hypothetical-protein
MKLVKALGALALPGIALGAAQLAAAEDTVPVQELVIVEETASPTLADARIPPDDSPYRGDLRPYGLFRPYRPFEPYRPFEPYRPLRAEPYRPFEPYRPFEPYRPFRPYGHFVPHRPFRPFRPFEPYDGRLRDRGRSEATPAGGCPMPAVNLQDHR
>NC_021658.1|WP_148314974.1|10760383_10760680_-|hypothetical-protein
MLAAMEEAQRAKVVELARRLIPTLTAEDIRNPHDFPGLDDPDWHFEDGQLAGIESVRFALRGLARDVLGDGEGREARERPESDGQPGAGREGGGTQGE
>NC_021658.1|WP_020739500.1|10759604_10760120_-|Smr/MutS-family-protein
MAGVRVLEDRVNRIPVTASRVERAALPTIASDPDEEARSRMRSLVIEGIKFETTDDSARIEGRRLDVDPRELRRLRRARYAVDGTLDLHGLRLEAAREAVEAFVCKRQRDGDRVVAIVHGKGNHSPGGHAVLRGEIAAWLSNGRVARHVAAFSTAPDAEGGAGAVLVLLAR
>NC_021658.1|WP_020739499.1|10758864_10759608_-|hypothetical-protein
MRPEARAEPAETPGHARRPDARATRGGVLPAARAARRALLSAAALLALLPACAPAPAAPPAPPPRPAPPPPPPSLGDGERGEYRSERFDLLLPLPDARGFRVEDGEGPWLVATHAASSTSLLVRTWREDGRASRAVCEARARLWRDLPRPDQSLTAVERRIDVPEGFDTVVAIGVADAPPGAPIDGFAVAFGGSGRRCFAFVAETRAAGPSAERLVAERLAAVVEISLGGLRLVRETAPAVPREPLP
>NC_021658.1|WP_020739498.1|10757980_10758817_+|hypothetical-protein
MGSAWTWLLERCAEIVGVTDGAAGSAGDAARRRRRLTLALLLSLLVGASCLLGDRWGAKGLLPAVALFVLAVQATRAVLAARASVWRAAALELDDPAQRPSERADPWFSPPTARVLCALASVIDAARRERYAIALERLPHVDRAALRPDEVRLLDAARALLSLGLGDPARAAQQAIVALPTGIDAIDARLGRVVLADAWKSPARLEAIERAWRRELQSGVTSEALERLLSLSRLRFAPRALEALKPAEARELSAEAWSIGEEELAAALEARARGGVYR
>NC_021658.1|WP_020739497.1|10756938_10757955_+|isocitrate/isopropylmalate-dehydrogenase-family-protein
MPYRITLIPGDGIGPEVVKATQDVISAAGVAVDWEIHHAGIEVAKLTGSPLPLPVIDAVRKNRIALKGPVTTPIGGGFRSVNVTLRQTLDLYANVRPIRSLPGVEPRFDVDMVIVRENTEGLYAGLELMILPGVAQSIKLTTERSSTRIAEFAFRYAKRHGRSKVTIVHKANIMKLSDGLALDCARRVAVGHPEVQLGEMIVDAAAMTMVREPNKLGVLVTENLYGDILSDLGAGLVGGLGIVPGANIGDEAAVFEAVHGSAPDIAGKGYANPTALVQSAVMMLRHLGEHEAADRIERALTAVYRAGQVRTRDLGGTASTDDFTRALCAEIEKPRAEA
>NC_021658.1|WP_044986538.1|10755788_10756670_-|OmpA-family-protein
MHPRVLKGRSLAFAAFLPAVIASFSLGCGYSEEEWKAQLDKYGRLQSQQQSTEQRLAETQKALEVEQAKVAELTRQLEAAGVDISKLNENLQATSTQVSQLSSTLEEREKALAEFKARARQLEQIKARFETLRKKLDELTKLGLAVNIRNNRMVISLPGDVLFDSGRETLKKEGKEILFKVATVVRNDPSLLNRYYQVAGHTDNKPLAGGQFRDNWGLSLMRAREVLLYLVSPADVKGGGGALPVAKWSAAGFADTDPVATNDTDEGRQKNRRCDLIVVPSVEEMLDLKAITQ
>NC_021658.1|WP_049949748.1|10754770_10755703_+|helix-turn-helix-transcriptional-regulator
MGLEGGPPPSLRLPATGQRSSPRGHAVQARVMTPTETAEHLARLGLDEVPARAFSYEDELPGAAYAWHTHARHQLLCPLAGTARLDVEDASFLLPPQRAALIPAGEPHATTRRDASIVSIYFEPAAFPSPLAAVRVFEVTALLREMVIYARRWPVARRPDDAAADTFFAAMADLIAPLLDRGATYRLPRGRTPPVQRAIACALGDVASADLARAAAFAGATERTLRRRFREETGVTWRAFVTRARVLRALDLLSGPSASVTQVAVDVGFQSLGAFAAAFRAVTGQTPSEFRRTAPPWPGGDGHSSWPEPT
>NC_021658.1|WP_020739505.1|10768219_10768975_+|hypothetical-protein
MRRIRRDATKVWHNPELHTAYGRGQPNSAGLPRPTQTGEDRRAAKQHRAALEALFSPRKEPEAEDGKGGRAKSGRDAASKAPGRIVLAPPPQSDPKAVERQRLLSKLLCASGRPNISKAANEFLRAGHTFPAEQDVYLQLLEHSDEQRIQEAIDELSGILVAELPKRRAVLESRLRSIEEYAEEPATREAAERLRRQVSGRPEAPGAGAPSAEPGSHARPSSREAALPHAAADGAAQRGDGGISEASVEAE
>NC_021658.1|WP_020739506.1|10768971_10769442_+|hypothetical-protein
MTRAEFEAELRKLIQAFETGTGNERCVACVACERCVDCTFCRGSKALQRCHYCVDSQRCSDSTHCRGCRDLIACSHCVASERCTQSSYLVRSIDCTGCTYCFGCVGLVRKDFHILNQPYDRSSYFKLTAKLMRELGLSTGSGAEPAPAPAARAAQR
>NC_021658.1|WP_020739507.1|10769444_10769894_+|D-tyrosyl-tRNA(Tyr)-deacylase
MRAVVQRALAARVEVDGQVVGAIERGLVAFVGAAKDDDEADADHVANKVAGLRVFSDEAGKMSRALADVRGGVLAISQFTLFGDVRRGLRPSFDGAMEPARAEALYERFVAALRARGLEVATGRFRADMRVFVENDGPVTILIDSKRTF
>NC_021658.1|WP_020739508.1|10769964_10770945_+|hypothetical-protein
MRISIVGAGALGRVYGVRLAAQGDDVTFVVRPERVEDARPFVIEQVNSADRRDTLERPRLAADIPADAEVVLVTVRFDQLAPGGAAPRPAEGRTVADLLLRGPSVPVVVLTPLLPPQRASLEEAARRRITPAMPSISGYLDERGVVRYWIVGFASTLIDDEGGAPAERPLLEELARRLTSADLPARLDPDVGAQNAATTTAFFPLIAAIDAGGGTSALLANEGVLGTALQATRECMALADRVGTVAPWTKLLTRAIRPFTLKPGFALARLVAPEALRFLDAHFGPKLHAQHLAMGAAVLAMGREHGVSLPALERLMGLIEGRTGAR
>NC_021658.1|WP_148314976.1|10771001_10772000_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MSVGCPSGVGPEVAVAGAASVEGVRSVLVGDEAVLRRAARLVRVAARRLVVVDGRAAIERLAPGAIGIWAGSARLSRPSAFGRPEAEDGAAQLAWIDEATDLVRDGVAAALVTGPASKHAIATSGAPGSADFLGHTEHLGRRLRAREVTMAFASGKLVTALVTTHVPLRDVPEAVNPREVARASVWLARLLADLGREKPRVAIAALNPHAGEGGLLGDEEQLRIAPGIRLAARRLARSGSAAELSGPVGAETAFRLAARGALDGVVAMYHDQATIPSKLLGFGEAVNVTLGLPIVRTSVDHGTAYDLAGTGKADPRGMREAIALAAQLASAR
>NC_021658.1|WP_063752065.1|10772107_10773049_-|response-regulator-transcription-factor
MARRSFIAIVGHGPDLEREEGAASVLRSLGADVRTLDLWDDPPRLFHDDESKARAIVVEALDRPDLAAAALRALRREPRLEEVGALVAVSVAQIARIEPSSGFDDFLLVPYVPAELYARVRLVEWRRSEFATEERVKVGAIVIDRAAHDVSVGGMHVPLTAKEFALLSYVCERRGKVVSRTELLRRVWGSQYEGGARTVDIHVRRLRAKLGAALPLVTLRGAGYRLESPLPGSGGPEGGDAARTAPRGAAGAEADGEGRGEPRDEDEDEDEDAEGDEDEAEDEDDDDAARAERRSGSSAHDAATPGRDRRITR
>NC_021658.1|WP_020739511.1|10773156_10774602_-|protease-TldD
MSRSQAYRAPFAPGEENAVDAALCERLLSVALSKGGDYADLFFEYRAGGGFTFDEGILKAASRGVSMGVGVRVQRGDATGYAYTEDLTWDAMRRAAETAAQIATGAGGTERIELRRRELPSRYELPSISLDAPGLAKRALLERASAAALAYDPSIIKAEASFVEEVREVLVATSDGRMAHDVQPLIRFGVRAIAERDGKRQEGSSGGGGRMTTAYFEDRSPEWHAKEAARQAVAMLDAREAPAGEMNVVLAPGDSGILLHEAVGHGLEADFNRKGTSNYAGRVGRDVASPLCTVVDDATLLQSRGTINVDDEGNEPERSTLIENGKLVGYMHDRLSARHYGLTPTGNGRRESFASAPMPRMTNTILLAGPHDPEEIMKSVKRGVFAKKFGGGQVDISNGDFVFSLTESYLIEDGKLTAPLKGVNLIGNGPEVLRRVTMLGHDVATSDGIWTCGKDGQSVPVGVGCPTIKIDRITVGGTRIG
>NC_021658.1|WP_020739512.1|10775167_10777924_+|tetratricopeptide-repeat-protein
MAVDRDKVLQTAQKLVERKRYDKAIAEYQKLVAEDPKDVRTLLKIGDLYLKTEEYVEAITTYERVGQFYSLQGFALKAIAVYKQIREIIHKHVPQYEDRFGHIVPRLAEIYTQLGLTSDALAAYDEVATRLLRAGRDRDAIDIFKRVVDLDPNNPLAYLRLAEALIRVRDYDGAIQRFGTAAELLLKLGRRDDALKVVERLLQHRPDARFARMAAEIYLDRGDPSDGMSALTKLQIAFKENPRDLETLALLARAFDLLGQPAKAIEVQKESARIAKEAGRADQFAALIAALVSRAPNDEGVRQLAAQLVPSSRGTRASIDVELDEDDEDEAEELEVEDVEPSSAAPIPLRAAQPSTAPVTSPRQLVSHAESLRRERQYDKAVALLKGGVARLPAARELREKLCDILIEAGDQDGAIEQMLAFAQQLSGEGAVDDAARLLDEVLLLEPGHAQATEMLNLLGYAVPQEDELSDEEHTGAEISPTANDAYASEVPSQDLYDPDAPLPAYTLDEDGVVEALPRRPELVTHLDDPFANEPPLPSFPIDDVEEVEDVEPLEELEDIDDEEETASVSPSRSPAHPLVIAASQAPPAPSSMPPPPVLAAPPALYSPAPPRPASVRPSSGRSVPPGSGRRADALDEDALEEVEFFAQHGMFEEARNILEEQLARLPNHPLLMERLREVTELASETRGERAATDNESGTRAVPRGSERPDEDRAFDIAESLKMIDELEVAPGSVTGVQDDPRQISVESVFEQFKAGVAAQISEGDASTHYDLGVAYKEMGLYADAIAEFELAARDPGRECVCQSMIGVTYLQMGNIEAGIDALIRGLHASHKTVEQELALTYEIADAYEMRGAPEQALYYFQRVARMSPSYSDPRGSVAERLRRIDVPKPAARAVGAEMIADEFDAAFDDLLPSGKLP
>NC_021658.1|WP_148314244.1|10778022_10778841_+|hypothetical-protein
MNRPLLFAALTSLLAAGCGAGIGTNARAGRPQDAAAKAADQAEREAPARAKGEADASAPAAEEAPARAPGDYVAYRFSGSFRKTPLLLTQRVVAREGDVLVVDVTLEDGKETEALRVRMSDAPSRRGEILGAAWIDGGAERPATLAAYDAMMAKTALAADENEEVLGTEAVNVEVGGGAIACQKTSFRVRIGRTKATMRTLQSDDFAWGDVGGEIPAEDGRVLYRAELVDRGHADARPSAPAAAAGAEPGLAPRPATVARSEDDGDGDDYED
>NC_021658.1|WP_148314245.1|10778828_10779986_-|uroporphyrinogen-III-synthase
MPSSAMPAPMTGSGPTSFSEVARESPLPWTPPASLLIGWLTGGSLANWSTARNPPALDPGYAARVSTPTHPLNDRPSRPASPDFAGRRVITFESRRAAEMASLIQRYGGVPVTAPTLREVSIERNERALDFARRLAGAELDLVILMTGVGTRALVAEAAPALEPGHGGDGAPDADAGAQGVSLMAAALSSVQLVVRGPKPAAALRELGVTRFVTVPEPNTWREILSVVRGLGDLSGKRIAVQEHGAPSHELYAGLEAAGARVTPVPVYRWALPEDTSALRQALRLLADGGAAITLFTSRAQVEHALLVAAEEGLVDRLRAGLARGMVASIGPVCTEALRAEGIEPDVEPEHPKMGHLVRAAAVRSGEVLARKESQGDAPPPAQSS

Crispr_ID: NC_021658_51

• CRISPR_ID: NC_021658_51
• CRISPR_location: 11366810-11366899
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_51

Consensus_repeat	Method
GTGAGCGAGCGCAGCGGCGAGAG	CRISPRCasFinder

spacers of NC_021658_51

>51.1|11366833|43|NC_021658|CRISPRCasFinder
CGTCGAGATGGGGAAATAGCCGAGCTTGAGCGTATGGAGGCGG

CRISPR arrays and Neighbor proteins around NC_021658_51

CRISPR arrays

The CRISPR arrays of NC_021658_51

>merge|NC_021658|51|11366810-11366899|CRISPRCasFinder
TTGAGGTCTGACAGCGGCGAGAGCGTCGAGATGGGGAAATAGCCGAGCTTGAGCGTATGGAGGCGGCTCAGCGAGCGGAGCGGGCTGATG

>NC_021658|51|44|11366810-11366899|CRISPRCasFinder
TTGAGGTCTGACAGCGGCGAGAG	CGTCGAGATGGGGAAATAGCCGAGCTTGAGCGTATGGAGGCGG
CTCAGCGAGCGGAGCGGGCTGATG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_044989315.1|11349744_11350347_-|glycoside-hydrolase-family-11-protein	unknown	unknown	gnl|CDD|366111
NC_021658.1|WP_148314305.1|11352222_11354628_+|glycosyl-hydrolase	unknown	unknown	gnl|CDD|200478
NC_021658.1|WP_044986653.1|11377607_11378582_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314307.1|11373673_11374066_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739939.1|11367971_11370797_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|226418
NC_021658.1|WP_020739930.1|11354695_11355718_-|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|225041
NC_021658.1|WP_044989317.1|11376192_11377554_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_148314306.1|11370881_11371520_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949900.1|11372460_11373519_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739935.1|11361342_11362380_-|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234948
NC_021658.1|WP_020739928.1|11351185_11351893_-|glutathione-S-transferase-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|183298
NC_021658.1|WP_044986651.1|11375276_11375765_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739941.1|11371723_11372398_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739931.1|11355930_11356416_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314308.1|11375752_11376169_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739932.1|11356551_11360625_+|thrombospondin-type-3-repeat-containing-protein	unknown	unknown	gnl|CDD|276965
NC_021658.1|WP_020739936.1|11363268_11364858_+|ATP-dependent-DNA-ligase	unknown	unknown	gnl|CDD|235108
NC_021658.1|WP_020739944.1|11374131_11375307_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080682535.1|11347967_11349167_+|glycoside-hydrolase-family-11-protein	unknown	unknown	gnl|CDD|366111
NC_021658.1|WP_020739937.1|11364873_11366355_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020739935.1|11361342_11362380_-|D-alanine--D-alanine-ligase	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.29049e-145
NC_021658.1|WP_148314305.1|11352222_11354628_+|glycosyl-hydrolase	gnl|CDD|200478	cd11339, AmyAc_bac_CMD_like_2, Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins. Cyclomaltodextrinase (CDase; EC3.2.1.54), neopullulanase (NPase; EC 3.2.1.135), and maltogenic amylase (MA; EC 3.2.1.133) catalyze the hydrolysis of alpha-(1,4) glycosidic linkages on a number of substrates including cyclomaltodextrins (CDs), pullulan, and starch. These enzymes hydrolyze CDs and starch to maltose and pullulan to panose by cleavage of alpha-1,4 glycosidic bonds whereas alpha-amylases essentially lack activity on CDs and pullulan. They also catalyze transglycosylation of oligosaccharides to the C3-, C4- or C6-hydroxyl groups of various acceptor sugar molecules. Since these proteins are nearly indistinguishable from each other, they are referred to as cyclomaltodextrinases (CMDs). This group of CMDs is bacterial. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	1.39476e-49
NC_021658.1|WP_020739928.1|11351185_11351893_-|glutathione-S-transferase-N-terminal-domain-containing-protein	gnl|CDD|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	6.02e-73
NC_021658.1|WP_020739932.1|11356551_11360625_+|thrombospondin-type-3-repeat-containing-protein	gnl|CDD|276965	sd00038, Kelch, Kelch repeat. Kelch repeats are 44 to 56 amino acids in length and form a four-stranded beta-sheet corresponding to a single blade of five to seven bladed beta propellers. The Kelch superfamily is a large evolutionary conserved protein family whose members are present throughout the cell and extracellularly, and have diverse activities. Kelch repeats are often in combination with other domains, like BTB and BACK or F-box domains.	4.808e-46
NC_021658.1|WP_044989315.1|11349744_11350347_-|glycoside-hydrolase-family-11-protein	gnl|CDD|366111	pfam00457, Glyco_hydro_11, Glycosyl hydrolases family 11.	3.56303e-91
NC_021658.1|WP_044989317.1|11376192_11377554_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.67673e-16
NC_021658.1|WP_020739930.1|11354695_11355718_-|NADP-dependent-oxidoreductase	gnl|CDD|225041	COG2130, COG2130, Putative NADP-dependent oxidoreductases [General function prediction only].	0
NC_021658.1|WP_020739936.1|11363268_11364858_+|ATP-dependent-DNA-ligase	gnl|CDD|235108	PRK03180, ligB, ATP-dependent DNA ligase; Reviewed.	0
NC_021658.1|WP_080682535.1|11347967_11349167_+|glycoside-hydrolase-family-11-protein	gnl|CDD|366111	pfam00457, Glyco_hydro_11, Glycosyl hydrolases family 11.	5.2282e-81
NC_021658.1|WP_020739939.1|11367971_11370797_-|tetratricopeptide-repeat-protein	gnl|CDD|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	2.39867e-26

Protein sequences

>NC_021658.1|WP_020739937.1|11364873_11366355_-|hypothetical-protein
MRITTSALLLLASSIILAGCGEIRETEPAASSSGDTSAGSWGSGGGAGGDAVGGGGAGGSGGALPAEEAWHRQISGPEMEDAMALAIDSGANVVLAGSSRGAADFGAGAMPLAGFEDLFIAKYADDGALRWVQRFGGGLVTATGIAVDANDGIAVVGHISSGPLEAGDLALDEPERDDIFVLALDRGGAPRWMHRLGGPGFDFGGRVAVGPGDDVVVAAQSGGRLTLARFAADGAVRFATDLGHLSGYASSFAPIGGVAVDLRGDILVAGNFSGGADLGGGAITGLRGDQAWVAKYSGEDGAHVWSRHFGVPEDHGMGLGDKAQTLLVDERGDVLIAGQFAVGADLGEGPIDDTGGAFLAKVAGEDGAVRWAKALPAAGVVSTGLSFTPDGRVALIASLRAPFDLGGGTVDERGSYIATYEPSTGAFVAQRRIVEVGTMISDTQNGFFGMGASAVDAKGNLAIVTSFYEEAQTGFGALKSEGWGDILLAHLPL
>NC_021658.1|WP_020739936.1|11363268_11364858_+|ATP-dependent-DNA-ligase
MLVSDLVATSDRVATTSSRLEKIGALADLLRRLSPEEVRIGVDWLAGRLRQGRIGLGPAMVTDARRAGPSAVEPALTLGEADAVFTEIARTSGSGSAAQRRAALGGLFARATELERDFFARLLVGELRQGALEAVMIEAVARAAGLPPASLRRAVMLASDAAEVAKAALLEGAPGLQRFSLQLLRPVQPMLAQAADDVASALGELRAAALEWKLDGARVQVHKAGDEVRVFSRSLNSVTKAVPEVVEAVRALPVRSIVLDGEAIAFRADGAPHPFQVTMRRFGRTLDVAGLRAELPLRALFFDVLHLDGEDLLDRSGSERAAALRQALDRSLRVPRIELPTEAEAEAFFADALARGHEGVMAKSLAAPYEAGRRGSSWLKVKRAHTLDLVVLAVEWGSGRRRGLLSNLHLGARDPGAGGFVMLGKTFKGMTDEMLAWQTQRLLELEITRDAYTVVVRPELVVEIAFDGVQASPQYPGGVALRFARVKRYRPDKAAGEASTIDEVRAIHAGALAHEAAERREAGGGGEEA
>NC_021658.1|WP_020739935.1|11361342_11362380_-|D-alanine--D-alanine-ligase
MVERQVRRRVGVVMGGSSGEREVSLRSGAAVAEALEARGYDVVRITLGDRFGTELCATLQRARLDAAFLALHGRLGEDGCVQGVLELAQIPYTGSSVLASALAMDKLKAKEMFRLHNVPTPPYYTVGAHQELDELEAVHGSFGFPVIVKPRGEGSSLGVTKAGSLEELRSALALAFEFDDAAIVERFVSGTEVNVGILDGKVLGAIEIVPKKGLYDYEAKYTPGMTEYHMPARLPPTRYRGVLNLAERAAQALGCTGAVRVDLLVTGGENEYVLEVNTLPGMTQTSLLPKIAAAAGYEFGDLCETILASARLHQPVRRRAPAASELRLSERGQAEKRLRLVKSAI
>NC_021658.1|WP_020739932.1|11356551_11360625_+|thrombospondin-type-3-repeat-containing-protein
MLAVVILVLAAAGWMSALGCAAGHDRAAAAAAQVQQRFPAQAAEVLGSSALDAPSARDGGFALGAAGPAGRGPRLQAELPRDGGGWVRLSGPGGFEVRVRETGASGPGAIVDGAVIYGRAGGASFWRAADGGIEEWLTVEPGAAPAGAPVAVWEVDGAALRQRGEAVEVVDAAGTPRLRVTAPRAFAEGGRPVAVRLEARGGEIALLAEASGELLLVDPLWRPVGAMAERRDGGHTATRLGGDDGRVLVAGGRGGEGYLASAELYDPADDGWAPAQPLSAARYEHAALLLDSGRVLVVGGSNGSSAQASAELYDPAEDRWIPAQSMSDARQGPTATRLDSGLILVVGGWSDGTHLASAELYDPREDTWTAAAPMSTGRYGHTATLLGDGRVLVTGGFDGLEALESAELYDPAANSWTPVQPMSAGRQRHAATLLDDGRVLVTGGAEIYWGEEEEEEEEEEREGEFASAEIYDPVSGSWAQTAPMNFGRSQHTATLLVDGRVLVAGGSAVVVESEWSGYLANAEIYDPTAGSWSDAPAMAVGRSGHTATLLPGGGVLVTGGNQGIDANAEVYDPSGASPWSEAAPMIRSHTRHTATLLADGRVLAAGGYGIDHIPIPSAEIFDPITRIWTEEAPMLAARDEHTATLLDGGQVLVAGGEGSSFIPIASAEVFDPIARTWTAAAPMITARSEHTATLLDDGRVLVAGGYGAGYIPIAGAEIFDPMTHTWTAAEPMTTARNQHTATLLDDGRVLVAGGYGADYLSIASAEIFDPVTRSWTAVEPMIDARYMHTATLLDDGRVLVAGGYGAEYVDLSSAEVYDPATHRWTARAPMSTTRYLHTATRLLDGRVLVAGKVVTNGLSGASAEVYDGATDSWSPAGTMYSERFGHTATLLRQGKILVTGGEGPGGILASAEIYSPVLPGAPCDTDADCAGDSCVDGVCCDAPCAGACMACSAAKKGAGPDGVCGPVQAGADPDDDCAAEAAATCGANGSCDGRGACQLWAQGTPCGAASCNGVSEVVDAPLCDGLGVCAEADTRSCGDYRCVAGACLAGCTFDTQCAEAAYCAEAGGDCLPKKPVGAACALPKECLSGLCLAGVCTRDSDDDGVADHEDNCPEVPNTSQANTDGGLSAGDRLGDACDDDDDADGHPDAADNCPLIANPNQADANGDGIGDACDCASPRKADGSACDDGNACTQTDTCQNGACVGSDPFLCPQPDAAVCRVAVCERATGNCGQRYKLDRAPCPGGECIAGGCLLAEGSGGSGAGGDGGSGGEGGAAASTGAGGSSSGGGGTGGDGGSSGDGGAPPKPARSSGGGTCRTTSPWSWPATSIRRRRATPSSGTSAASRGGRSPRRPRRRR
>NC_021658.1|WP_020739931.1|11355930_11356416_+|hypothetical-protein
MESLNAIQLPEELREPPPRPWAALRHARHQLAGVGYALLVWAGLLGVGSLYRHIDLVAMLVAFSFAVMPFVLLYQVLGSYTACRLALRGAPSAAQIYEGVVVTRFGTVNVWHVVVAGQHVRIRADAPLLKSMVVLVTPETSGGKRRVGVYHPKIGICTSLV
>NC_021658.1|WP_020739930.1|11354695_11355718_-|NADP-dependent-oxidoreductase
MTSQRNRKIVLAARPVGEPTPSDFKLIEEELAEPGEGRALLRTLYLSLDPYMRGRMSAGPSYAPPVEVGDVMVGGAVSEVLRSSVDGLAPGDLVEGRTGWQAYAITDGSGLRKVDPALGPISTALGVLGMPGMTAYTGLLNLGQPKPGETVVVAAASGAVGSVVGQIAKIKGCRAIGVAGGQRKCDYVVRELGFDACLDHRGPDLAARLKEACPGGIDVYFENVGGAVFEAVLPLLNPFARVPVCGLIAHYNDTAPHPGPDRLPGLMKQVLAKRLSLRGFIVGDFAEQRPEFLQETSRWIREGRIKYREDIVDGLEKAPEAFIGLLKGENFGKLLVRVAS
>NC_021658.1|WP_148314305.1|11352222_11354628_+|glycosyl-hydrolase
MSRRRTPFVMSAVYAAMLLAVPLACGDDHELDAGQGKGAGGGEAGSGGGAGGGGGGLGGGGGLGGSGGADGGGGNGGSGGATWQGDVLCPTSFAFNAPPGATDVRVPGEWNGFDLGTAPELREGGAQGQLVATVDLPPGLHAYKITYRYGGELAWVLDPAEGRRKYVDGIENSAVKVPDCRLPALSVASSQVARAAAGEGAFEARLAYRDGIEGAGPDADAFEAMLQDQDGDTRPLTEQEISVDERGDVRIDVRGLDDGKYRITLRGATRSGRVGEPLRLVFWVEAEPFSWEDALIYMVVTDRYRDGDPALNAPATPGADPRGDWAGGDLEGLRRSIEDGTLDALGVRAIWLTPFQENPAGAYPASDGVHQVTGYHGYWPIKAREVDPRLGGAEALRALVAEAHRHGIRVLQDFVVNHVHEAHEYVASHPGWFRTGCVCGTDGCDWTSHALDCMFAGYLPDVNHTVPEANAAFVADAVYWLDEFDLDGLRVDAVKHVEEIATRNLAAEVREAFEPAGTRYFLMGETAMGWNDCAPPCNDENYGTIAKYIGPQGLDGQFDFVLYHGVSYRTFAWGDRGMLHAAYWVEDGQNRWPEGAIMTPYIGSHDTARFATLADYRGQDAAHGRDVPTRQWSDTAEAPASSDVYARVRLAMAWLLGLPGAPLLYYGDEYGEWGGVDPNNRSLWRAEDELTPDERETLDFVRQLGAARQGVPALRRGAYVNLTATEDTLVFGRRLAGGRSAVVALTRAATAQRISVEVADALGLPAGTALTDALGGGAETVSATGMLSMTIPPGGAVILAP
>NC_021658.1|WP_020739928.1|11351185_11351893_-|glutathione-S-transferase-N-terminal-domain-containing-protein
MTDLSSYPITRKWPAQHPDRIQLYSLATPNGVKVSIALEEMGLPYEAHLVSFDTNDQLSPEFLSLNPNNKIPAILDPQGPGGKPLALFESGAILLYLAEKSGKLLPQDAARRYETIQWVMFQMGGIGPMFGQLGFFHKFAGKDYEDKRPRDRYASESKRLLGVLDGHLRGRAWMLGDDYTIADVAIFPWVRNLVGFYGAGEVVGFDDYKEVKRVLDAFAARPAVVRGLGVPSRNG
>NC_021658.1|WP_044989315.1|11349744_11350347_-|glycoside-hydrolase-family-11-protein
MPAACTEPDREVCNNGTNMHCGYTYEYWKDSGSGCLTNTSEGFSVNWSNINNLLGRKGIRPGSKDQIVTYEADYRPNGNSYLCVYGWTKGPLVEYYIVDSWGTWRPPGGEGHMGTVESDGGTYDIYRTQRVNQPSIEGTATFYQFWSVRKEKRSSGTITVANHFNAWQRAGMNMGNLYEVSMTVEGYQSSGEADVKFSME
>NC_021658.1|WP_080682535.1|11347967_11349167_+|glycoside-hydrolase-family-11-protein
MRIATLLGYLSATVACGLLACSVEQIADDEDAALLESAVESSDRSVSATLAIQSDWGNGYCASVKVTNNTRTNPGLTGWSVVVGLNGSTTNNVWNANASGSGGQFTATNVGHNGSVAQGKSTEFGFCANGTGRPSVVSVTGNGGTISGGTTTSSSSSSSVSSTTSSSSTSSSTTGGGGAGGSGGAGGGGGAGGGGGAGGGGSTCTAANSQYCSNQTGTHCGYTFEYWKDNGTGCLTNTADGFNVTWSNINNLLGRKGIRPGTKNTVVNYTADYRPNGNSYMGVYGWTKGPLIEYYIVDSWGNWRPPGGEGFMGTVTSDGGTYDIYRTQRVNQPSIEGNTTFYQYWSVRKDKRSSGTITVANHFNAWASKGMNLGSLYEVSMLVEGYQSSGSANVQFSMR
>NC_021658.1|WP_020739939.1|11367971_11370797_-|tetratricopeptide-repeat-protein
MADAARPRRRHLAVPASRFLGRERELAAIAELFLRGERLVTVWGPAGMGKTRLALELASRWDEARPAEAVWLCELTACRDLRAVCGAVARAIGAQVAAGRREATLVERIGRALATEGPALFVLDNLEHVLEQAAPALDAWVRAAPEVRFLATSRERTRLPGEIGCELGPLELPAEGSAERSAAVALFLDRAAAHRGGAPAGDARLADVAALVRRLEGIPLAIELAAAREGVLGVRGLLARLGSRLDLLAGAARGREARQATMRSAIEWSWDLLDDRERRALACCSVFRGPFSLAAAAAVLAAPDAAAIDRIEALRDKSLLRAAPPGSDGATRFALYEGVRELAAEKLAERGEREAAAERHAAFYLAAGEAAAADFERRGALDALNRIAGDLEELLAVAEGALAAAATPRAGAVAEGGVAAAPTPRAPSSAAAEGTVAAAPRAAAERALRALSAIEPVLSTRGPFGAQLELLDRALAAAEALAADPRVVARALAARGRARRLRGQAEAALEDLERARAQAAALDEAALLSGILADLGVLHHGRRDMERARGHYEQALALHRALGDRRAEGRALGNLGALHHDERREAEAAAYYERAIAIAAEIGDGRQEGIFSTNAGLLEQERGAPALARRRYERAAAILGEVGDLRLLAITLGNLGALHHEEGRLADARACHGRAVALLREVGDRRSEAIALCRLGAALASVGEVGEARRALEPAERLLAQLGDEPDVELARVASGFVDLALAQAARRAGQGDEAAAHVGAARRRIARAREGSPSSASRSDDVRLLLRILERSLAALGDLAEARAGVERELLLTEGARFVRPPGGGWHDLRERHAARRLLLALAEQQRCAPGRGLSLAALKEAGWPGERILPEAAANRIYVAMNQLRKLGMKPWLRRDAEGYSLDPALPVHYAAVEPGARGGGDSRGGTGEGEGRGGGKRR
>NC_021658.1|WP_148314306.1|11370881_11371520_-|hypothetical-protein
MGSVHRSGRIRLCMKTARALALATGMLGALLCAACAADPEPAPPKISVGAVDGTDAVLAVVRGEGAVTLYVCGGASTYATMTRWFEGPEDPSGAFSIESGGWIATADPGGESGRLRAPDGAELAFRARPAARGSIEGLYAADDGGCRTGAVVFTPEGAESPALQGTWCAVGDRFAQVTPLRPLSALDRRGIQVQVELDGARKNLLVTPLGRP
>NC_021658.1|WP_020739941.1|11371723_11372398_+|hypothetical-protein
MNHRCGVLLVMLACGCSIVDPSDRDELRDQIAAMPPEEISRLRILGMNSAALDWLKGRPPGDQMGKIQCRYQAGGQWTNWADQEPPFIVDDMRDCLIRRPFLVTYVMCMEEWEALQRQERKTNLMNSLPIPGGATVECRFVWDFRYEPEKAPAEVTNPEAVDTDDIINTLIALPAPPPGWAFPRLVPLLCPLGAGPGWGCPPKPADPTGGQPTDPTGGQPGDRP
>NC_021658.1|WP_049949900.1|11372460_11373519_+|hypothetical-protein
MFTTKDPELWKWHLENLAQLCAAAWDDDLHDEDRAWAESYRKKFSRWIGDSGPPGGGHRVNAGPRRSPRGRFDGEPTPPWPMLLEAVQSAFFSMMEASKEMRPDTSERAVEDPMSRLHRTYLWRTLTSEDTAEELRAEALRAFRRGYRIGRRGKPGTLTRAIPPMLDAPAIWKLGAPALPGPSAARERALRALPAPDDPTELMEIEQELRALYTSAWRDDVPDEDRIWAARYRETCTLWVNQHRRGALAQSAYEGYLQSSDGRFGGEPAGPWRSVSAFAKEPWCSFVDRVEDAPEGESEPETAAAAAWEYWDAHCREAPPWDSDPDQAHWLAALRAARRKAQDDDGPPEMGR
>NC_021658.1|WP_148314307.1|11373673_11374066_+|hypothetical-protein
MPSITGLRRWPIREAVDIGIGADVGLFGLGGDARWLGVLGGPAAAIRAMPFRAPLSLELTTRLDFGRIPVCNAWGLCLRYLGLFPAVEAGAAYLSTQHVAIVATCGVRFINTLAWSGVSVEPAAAGRIFW
>NC_021658.1|WP_020739944.1|11374131_11375307_+|hypothetical-protein
MPSIANPKPLVRRSLCEASLGQRLFSTRDPETWTAHFEALGTLCADAWLDDLPEADRAWAAAHRERFRRWIDVPGPNGADPRASASALQSDPVPVPGELTLPWPMLLGAVESAFFASVRVFEVTPAGERERAAADAAARLHRSYLWRTLSSDAAAAPHRPEALRAFQRGFELGRGTPSSSRMPVPPMLEPPWYWGAGLPEYPGPMATRERALRTMSISAGRAEWLSRNRELRALYASAWRGDVPEEDREWAQVVRDCCTTHVNRRRRDAIARTAYEGYLQSSGGLFDGEPGRPWPMLSHTTSEPWRAFAERVEDAPEGESELATAEAAARELWETLYAKFPPWDGDPDQAHWLAALRAARAKALAGDAPPENACCPQETPPGYSAPLQSET
>NC_021658.1|WP_044986651.1|11375276_11375765_-|hypothetical-protein
MHDMSEQLVGALSAVLWVAFGSSASGCVSHPEVSGKVIITRDDEELVLDTGGNGTRVVDASGEVAGGCIVRNQTELSVTVQKEGVAFSFFDLVDQAGLPHVSAEIDGKLYQGACEIIVEERQGDPYEADVAAGPCDLVRLFDGAKARLEMAVFHVSDCSGAE
>NC_021658.1|WP_148314308.1|11375752_11376169_-|hypothetical-protein
MLLFIGVSAGLGCAPDLDCPGSGPHEGDPAVWLWDGTQNEAPGCAEATEVLWEGWRKGSSTAPESPTFARACAGVVREDIPDGYTLCVIPTEVEEICWDGYADHAIYVEEDGEEHVMCCTPAGNPPTVLPQGYGGCTT
>NC_021658.1|WP_044989317.1|11376192_11377554_-|protein-kinase
MVRTFLAQQVGDEGATVWLHLREGQSMDRTAFASELQRLQEIARAVPQLEPVLYGDAGGLSAWVACRRSHGISLKDATRGADLGATALQMVIDVARAIQRCHALGWCHGALGPDRVFITSKRDYSINQFGLVRLFRIEPHEAAREPLVAPPELLRGDRVGPRADVYGLGTLLYELVCRRSLDAGLPGTLGAQRDKPVIPVGTPRAVAAAIEMALEEDPRRRYRNVDHFITVLEGLVEAWPTLDLEPSGDEEMAVVTGGAPSTLRSSHLDAPRSPAPVTEEPDARSSEVEPAASLLNDDEPQHPEIPSLDVPSWTAPEPQELVLSPPPSLVRGPGRAPMMAPSKAADTPPRRLAGRIAVSVAAMAVLCAGVLLTRPARIVLRAEKLSAALVQQVSALPEGRRSPPPPVAEPTPPKKADGRPRVALSRRAGVAARAELRRPYCEAGDVSCGPALY
>NC_021658.1|WP_044986653.1|11377607_11378582_-|hypothetical-protein
MLRSALVIGGSKAAAVAMFLLALPLASAASPPRPPPPPPRSPRVAALVREAEAAFDRLEIARARHLWAQIYELERSTVAICQLGQLDRRLERWVDAAGELTRCVQEMRPPATPMERRLHDTRHADLAAARRQVTELRVFAPAGAAPVLVDGRIVDESGRIYVEPGQHEVTAALPDGRKARSTVRVTAGDARAVLLSPEPARLRPAAPPPARPAGAPAQPAAPPAPWLLYAGSAASGAFLVSGIVLHVVASLQDSALQAEMCKPRSTGNPKLLEELHAVEVQQHISTAALVAGTALGAATLVVAMLPSGAQIRAHGAGAEVRFSW

Crispr_ID: NC_021658_52

• CRISPR_ID: NC_021658_52
• CRISPR_location: 11367008-11367144
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_021658_52

Consensus_repeat	Method
GTGAGCGAGCGCAGCGGCGAGAG	CRISPRCasFinder

spacers of NC_021658_52

>52.1|11367031|43|NC_021658|CRISPRCasFinder
ATCGACGATCTGGTGGCCCCCGAGGCCCAGGGAGCGCAGCTCG
>52.2|11367097|25|NC_021658|CRISPRCasFinder
GTTGCTGACCTGGCCGCCCCAGAGG

CRISPR arrays and Neighbor proteins around NC_021658_52

CRISPR arrays

The CRISPR arrays of NC_021658_52

>merge|NC_021658|52|11367008-11367144|CRISPRCasFinder
ATGAGCGAGCGCAGCGGCGCGAGATCGACGATCTGGTGGCCCCCGAGGCCCAGGGAGCGCAGCTCGGTGAGCGAGCGCAGCGGCGAGAGGTTGCTGACCTGGCCGCCCCAGAGGTTTAGGGAGCGCAGCCCCGTGAG

>NC_021658|52|45|11367008-11367144|CRISPRCasFinder
ATGAGCGAGCGCAGCGGCGCGAG	ATCGACGATCTGGTGGCCCCCGAGGCCCAGGGAGCGCAGCTCG
GTGAGCGAGCGCAGCGGCGAGAG	GTTGCTGACCTGGCCGCCCCAGAGG
TTTAGGGAGCGCAGCCCCGTGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_044989315.1|11349744_11350347_-|glycoside-hydrolase-family-11-protein	unknown	unknown	gnl|CDD|366111
NC_021658.1|WP_148314305.1|11352222_11354628_+|glycosyl-hydrolase	unknown	unknown	gnl|CDD|200478
NC_021658.1|WP_044986653.1|11377607_11378582_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314307.1|11373673_11374066_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739939.1|11367971_11370797_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|226418
NC_021658.1|WP_020739930.1|11354695_11355718_-|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|225041
NC_021658.1|WP_044989317.1|11376192_11377554_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_148314306.1|11370881_11371520_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949900.1|11372460_11373519_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739935.1|11361342_11362380_-|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234948
NC_021658.1|WP_020739928.1|11351185_11351893_-|glutathione-S-transferase-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|183298
NC_021658.1|WP_044986651.1|11375276_11375765_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739941.1|11371723_11372398_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739931.1|11355930_11356416_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314308.1|11375752_11376169_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020739932.1|11356551_11360625_+|thrombospondin-type-3-repeat-containing-protein	unknown	unknown	gnl|CDD|276965
NC_021658.1|WP_020739936.1|11363268_11364858_+|ATP-dependent-DNA-ligase	unknown	unknown	gnl|CDD|235108
NC_021658.1|WP_020739944.1|11374131_11375307_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_080682535.1|11347967_11349167_+|glycoside-hydrolase-family-11-protein	unknown	unknown	gnl|CDD|366111
NC_021658.1|WP_020739937.1|11364873_11366355_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020739935.1|11361342_11362380_-|D-alanine--D-alanine-ligase	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.29049e-145
NC_021658.1|WP_148314305.1|11352222_11354628_+|glycosyl-hydrolase	gnl|CDD|200478	cd11339, AmyAc_bac_CMD_like_2, Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins. Cyclomaltodextrinase (CDase; EC3.2.1.54), neopullulanase (NPase; EC 3.2.1.135), and maltogenic amylase (MA; EC 3.2.1.133) catalyze the hydrolysis of alpha-(1,4) glycosidic linkages on a number of substrates including cyclomaltodextrins (CDs), pullulan, and starch. These enzymes hydrolyze CDs and starch to maltose and pullulan to panose by cleavage of alpha-1,4 glycosidic bonds whereas alpha-amylases essentially lack activity on CDs and pullulan. They also catalyze transglycosylation of oligosaccharides to the C3-, C4- or C6-hydroxyl groups of various acceptor sugar molecules. Since these proteins are nearly indistinguishable from each other, they are referred to as cyclomaltodextrinases (CMDs). This group of CMDs is bacterial. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	1.39476e-49
NC_021658.1|WP_020739928.1|11351185_11351893_-|glutathione-S-transferase-N-terminal-domain-containing-protein	gnl|CDD|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	6.02e-73
NC_021658.1|WP_020739932.1|11356551_11360625_+|thrombospondin-type-3-repeat-containing-protein	gnl|CDD|276965	sd00038, Kelch, Kelch repeat. Kelch repeats are 44 to 56 amino acids in length and form a four-stranded beta-sheet corresponding to a single blade of five to seven bladed beta propellers. The Kelch superfamily is a large evolutionary conserved protein family whose members are present throughout the cell and extracellularly, and have diverse activities. Kelch repeats are often in combination with other domains, like BTB and BACK or F-box domains.	4.808e-46
NC_021658.1|WP_044989315.1|11349744_11350347_-|glycoside-hydrolase-family-11-protein	gnl|CDD|366111	pfam00457, Glyco_hydro_11, Glycosyl hydrolases family 11.	3.56303e-91
NC_021658.1|WP_044989317.1|11376192_11377554_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.67673e-16
NC_021658.1|WP_020739930.1|11354695_11355718_-|NADP-dependent-oxidoreductase	gnl|CDD|225041	COG2130, COG2130, Putative NADP-dependent oxidoreductases [General function prediction only].	0
NC_021658.1|WP_020739936.1|11363268_11364858_+|ATP-dependent-DNA-ligase	gnl|CDD|235108	PRK03180, ligB, ATP-dependent DNA ligase; Reviewed.	0
NC_021658.1|WP_080682535.1|11347967_11349167_+|glycoside-hydrolase-family-11-protein	gnl|CDD|366111	pfam00457, Glyco_hydro_11, Glycosyl hydrolases family 11.	5.2282e-81
NC_021658.1|WP_020739939.1|11367971_11370797_-|tetratricopeptide-repeat-protein	gnl|CDD|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	2.39867e-26

Protein sequences

>NC_021658.1|WP_020739937.1|11364873_11366355_-|hypothetical-protein
MRITTSALLLLASSIILAGCGEIRETEPAASSSGDTSAGSWGSGGGAGGDAVGGGGAGGSGGALPAEEAWHRQISGPEMEDAMALAIDSGANVVLAGSSRGAADFGAGAMPLAGFEDLFIAKYADDGALRWVQRFGGGLVTATGIAVDANDGIAVVGHISSGPLEAGDLALDEPERDDIFVLALDRGGAPRWMHRLGGPGFDFGGRVAVGPGDDVVVAAQSGGRLTLARFAADGAVRFATDLGHLSGYASSFAPIGGVAVDLRGDILVAGNFSGGADLGGGAITGLRGDQAWVAKYSGEDGAHVWSRHFGVPEDHGMGLGDKAQTLLVDERGDVLIAGQFAVGADLGEGPIDDTGGAFLAKVAGEDGAVRWAKALPAAGVVSTGLSFTPDGRVALIASLRAPFDLGGGTVDERGSYIATYEPSTGAFVAQRRIVEVGTMISDTQNGFFGMGASAVDAKGNLAIVTSFYEEAQTGFGALKSEGWGDILLAHLPL
>NC_021658.1|WP_020739936.1|11363268_11364858_+|ATP-dependent-DNA-ligase
MLVSDLVATSDRVATTSSRLEKIGALADLLRRLSPEEVRIGVDWLAGRLRQGRIGLGPAMVTDARRAGPSAVEPALTLGEADAVFTEIARTSGSGSAAQRRAALGGLFARATELERDFFARLLVGELRQGALEAVMIEAVARAAGLPPASLRRAVMLASDAAEVAKAALLEGAPGLQRFSLQLLRPVQPMLAQAADDVASALGELRAAALEWKLDGARVQVHKAGDEVRVFSRSLNSVTKAVPEVVEAVRALPVRSIVLDGEAIAFRADGAPHPFQVTMRRFGRTLDVAGLRAELPLRALFFDVLHLDGEDLLDRSGSERAAALRQALDRSLRVPRIELPTEAEAEAFFADALARGHEGVMAKSLAAPYEAGRRGSSWLKVKRAHTLDLVVLAVEWGSGRRRGLLSNLHLGARDPGAGGFVMLGKTFKGMTDEMLAWQTQRLLELEITRDAYTVVVRPELVVEIAFDGVQASPQYPGGVALRFARVKRYRPDKAAGEASTIDEVRAIHAGALAHEAAERREAGGGGEEA
>NC_021658.1|WP_020739935.1|11361342_11362380_-|D-alanine--D-alanine-ligase
MVERQVRRRVGVVMGGSSGEREVSLRSGAAVAEALEARGYDVVRITLGDRFGTELCATLQRARLDAAFLALHGRLGEDGCVQGVLELAQIPYTGSSVLASALAMDKLKAKEMFRLHNVPTPPYYTVGAHQELDELEAVHGSFGFPVIVKPRGEGSSLGVTKAGSLEELRSALALAFEFDDAAIVERFVSGTEVNVGILDGKVLGAIEIVPKKGLYDYEAKYTPGMTEYHMPARLPPTRYRGVLNLAERAAQALGCTGAVRVDLLVTGGENEYVLEVNTLPGMTQTSLLPKIAAAAGYEFGDLCETILASARLHQPVRRRAPAASELRLSERGQAEKRLRLVKSAI
>NC_021658.1|WP_020739932.1|11356551_11360625_+|thrombospondin-type-3-repeat-containing-protein
MLAVVILVLAAAGWMSALGCAAGHDRAAAAAAQVQQRFPAQAAEVLGSSALDAPSARDGGFALGAAGPAGRGPRLQAELPRDGGGWVRLSGPGGFEVRVRETGASGPGAIVDGAVIYGRAGGASFWRAADGGIEEWLTVEPGAAPAGAPVAVWEVDGAALRQRGEAVEVVDAAGTPRLRVTAPRAFAEGGRPVAVRLEARGGEIALLAEASGELLLVDPLWRPVGAMAERRDGGHTATRLGGDDGRVLVAGGRGGEGYLASAELYDPADDGWAPAQPLSAARYEHAALLLDSGRVLVVGGSNGSSAQASAELYDPAEDRWIPAQSMSDARQGPTATRLDSGLILVVGGWSDGTHLASAELYDPREDTWTAAAPMSTGRYGHTATLLGDGRVLVTGGFDGLEALESAELYDPAANSWTPVQPMSAGRQRHAATLLDDGRVLVTGGAEIYWGEEEEEEEEEEREGEFASAEIYDPVSGSWAQTAPMNFGRSQHTATLLVDGRVLVAGGSAVVVESEWSGYLANAEIYDPTAGSWSDAPAMAVGRSGHTATLLPGGGVLVTGGNQGIDANAEVYDPSGASPWSEAAPMIRSHTRHTATLLADGRVLAAGGYGIDHIPIPSAEIFDPITRIWTEEAPMLAARDEHTATLLDGGQVLVAGGEGSSFIPIASAEVFDPIARTWTAAAPMITARSEHTATLLDDGRVLVAGGYGAGYIPIAGAEIFDPMTHTWTAAEPMTTARNQHTATLLDDGRVLVAGGYGADYLSIASAEIFDPVTRSWTAVEPMIDARYMHTATLLDDGRVLVAGGYGAEYVDLSSAEVYDPATHRWTARAPMSTTRYLHTATRLLDGRVLVAGKVVTNGLSGASAEVYDGATDSWSPAGTMYSERFGHTATLLRQGKILVTGGEGPGGILASAEIYSPVLPGAPCDTDADCAGDSCVDGVCCDAPCAGACMACSAAKKGAGPDGVCGPVQAGADPDDDCAAEAAATCGANGSCDGRGACQLWAQGTPCGAASCNGVSEVVDAPLCDGLGVCAEADTRSCGDYRCVAGACLAGCTFDTQCAEAAYCAEAGGDCLPKKPVGAACALPKECLSGLCLAGVCTRDSDDDGVADHEDNCPEVPNTSQANTDGGLSAGDRLGDACDDDDDADGHPDAADNCPLIANPNQADANGDGIGDACDCASPRKADGSACDDGNACTQTDTCQNGACVGSDPFLCPQPDAAVCRVAVCERATGNCGQRYKLDRAPCPGGECIAGGCLLAEGSGGSGAGGDGGSGGEGGAAASTGAGGSSSGGGGTGGDGGSSGDGGAPPKPARSSGGGTCRTTSPWSWPATSIRRRRATPSSGTSAASRGGRSPRRPRRRR
>NC_021658.1|WP_020739931.1|11355930_11356416_+|hypothetical-protein
MESLNAIQLPEELREPPPRPWAALRHARHQLAGVGYALLVWAGLLGVGSLYRHIDLVAMLVAFSFAVMPFVLLYQVLGSYTACRLALRGAPSAAQIYEGVVVTRFGTVNVWHVVVAGQHVRIRADAPLLKSMVVLVTPETSGGKRRVGVYHPKIGICTSLV
>NC_021658.1|WP_020739930.1|11354695_11355718_-|NADP-dependent-oxidoreductase
MTSQRNRKIVLAARPVGEPTPSDFKLIEEELAEPGEGRALLRTLYLSLDPYMRGRMSAGPSYAPPVEVGDVMVGGAVSEVLRSSVDGLAPGDLVEGRTGWQAYAITDGSGLRKVDPALGPISTALGVLGMPGMTAYTGLLNLGQPKPGETVVVAAASGAVGSVVGQIAKIKGCRAIGVAGGQRKCDYVVRELGFDACLDHRGPDLAARLKEACPGGIDVYFENVGGAVFEAVLPLLNPFARVPVCGLIAHYNDTAPHPGPDRLPGLMKQVLAKRLSLRGFIVGDFAEQRPEFLQETSRWIREGRIKYREDIVDGLEKAPEAFIGLLKGENFGKLLVRVAS
>NC_021658.1|WP_148314305.1|11352222_11354628_+|glycosyl-hydrolase
MSRRRTPFVMSAVYAAMLLAVPLACGDDHELDAGQGKGAGGGEAGSGGGAGGGGGGLGGGGGLGGSGGADGGGGNGGSGGATWQGDVLCPTSFAFNAPPGATDVRVPGEWNGFDLGTAPELREGGAQGQLVATVDLPPGLHAYKITYRYGGELAWVLDPAEGRRKYVDGIENSAVKVPDCRLPALSVASSQVARAAAGEGAFEARLAYRDGIEGAGPDADAFEAMLQDQDGDTRPLTEQEISVDERGDVRIDVRGLDDGKYRITLRGATRSGRVGEPLRLVFWVEAEPFSWEDALIYMVVTDRYRDGDPALNAPATPGADPRGDWAGGDLEGLRRSIEDGTLDALGVRAIWLTPFQENPAGAYPASDGVHQVTGYHGYWPIKAREVDPRLGGAEALRALVAEAHRHGIRVLQDFVVNHVHEAHEYVASHPGWFRTGCVCGTDGCDWTSHALDCMFAGYLPDVNHTVPEANAAFVADAVYWLDEFDLDGLRVDAVKHVEEIATRNLAAEVREAFEPAGTRYFLMGETAMGWNDCAPPCNDENYGTIAKYIGPQGLDGQFDFVLYHGVSYRTFAWGDRGMLHAAYWVEDGQNRWPEGAIMTPYIGSHDTARFATLADYRGQDAAHGRDVPTRQWSDTAEAPASSDVYARVRLAMAWLLGLPGAPLLYYGDEYGEWGGVDPNNRSLWRAEDELTPDERETLDFVRQLGAARQGVPALRRGAYVNLTATEDTLVFGRRLAGGRSAVVALTRAATAQRISVEVADALGLPAGTALTDALGGGAETVSATGMLSMTIPPGGAVILAP
>NC_021658.1|WP_020739928.1|11351185_11351893_-|glutathione-S-transferase-N-terminal-domain-containing-protein
MTDLSSYPITRKWPAQHPDRIQLYSLATPNGVKVSIALEEMGLPYEAHLVSFDTNDQLSPEFLSLNPNNKIPAILDPQGPGGKPLALFESGAILLYLAEKSGKLLPQDAARRYETIQWVMFQMGGIGPMFGQLGFFHKFAGKDYEDKRPRDRYASESKRLLGVLDGHLRGRAWMLGDDYTIADVAIFPWVRNLVGFYGAGEVVGFDDYKEVKRVLDAFAARPAVVRGLGVPSRNG
>NC_021658.1|WP_044989315.1|11349744_11350347_-|glycoside-hydrolase-family-11-protein
MPAACTEPDREVCNNGTNMHCGYTYEYWKDSGSGCLTNTSEGFSVNWSNINNLLGRKGIRPGSKDQIVTYEADYRPNGNSYLCVYGWTKGPLVEYYIVDSWGTWRPPGGEGHMGTVESDGGTYDIYRTQRVNQPSIEGTATFYQFWSVRKEKRSSGTITVANHFNAWQRAGMNMGNLYEVSMTVEGYQSSGEADVKFSME
>NC_021658.1|WP_080682535.1|11347967_11349167_+|glycoside-hydrolase-family-11-protein
MRIATLLGYLSATVACGLLACSVEQIADDEDAALLESAVESSDRSVSATLAIQSDWGNGYCASVKVTNNTRTNPGLTGWSVVVGLNGSTTNNVWNANASGSGGQFTATNVGHNGSVAQGKSTEFGFCANGTGRPSVVSVTGNGGTISGGTTTSSSSSSSVSSTTSSSSTSSSTTGGGGAGGSGGAGGGGGAGGGGGAGGGGSTCTAANSQYCSNQTGTHCGYTFEYWKDNGTGCLTNTADGFNVTWSNINNLLGRKGIRPGTKNTVVNYTADYRPNGNSYMGVYGWTKGPLIEYYIVDSWGNWRPPGGEGFMGTVTSDGGTYDIYRTQRVNQPSIEGNTTFYQYWSVRKDKRSSGTITVANHFNAWASKGMNLGSLYEVSMLVEGYQSSGSANVQFSMR
>NC_021658.1|WP_020739939.1|11367971_11370797_-|tetratricopeptide-repeat-protein
MADAARPRRRHLAVPASRFLGRERELAAIAELFLRGERLVTVWGPAGMGKTRLALELASRWDEARPAEAVWLCELTACRDLRAVCGAVARAIGAQVAAGRREATLVERIGRALATEGPALFVLDNLEHVLEQAAPALDAWVRAAPEVRFLATSRERTRLPGEIGCELGPLELPAEGSAERSAAVALFLDRAAAHRGGAPAGDARLADVAALVRRLEGIPLAIELAAAREGVLGVRGLLARLGSRLDLLAGAARGREARQATMRSAIEWSWDLLDDRERRALACCSVFRGPFSLAAAAAVLAAPDAAAIDRIEALRDKSLLRAAPPGSDGATRFALYEGVRELAAEKLAERGEREAAAERHAAFYLAAGEAAAADFERRGALDALNRIAGDLEELLAVAEGALAAAATPRAGAVAEGGVAAAPTPRAPSSAAAEGTVAAAPRAAAERALRALSAIEPVLSTRGPFGAQLELLDRALAAAEALAADPRVVARALAARGRARRLRGQAEAALEDLERARAQAAALDEAALLSGILADLGVLHHGRRDMERARGHYEQALALHRALGDRRAEGRALGNLGALHHDERREAEAAAYYERAIAIAAEIGDGRQEGIFSTNAGLLEQERGAPALARRRYERAAAILGEVGDLRLLAITLGNLGALHHEEGRLADARACHGRAVALLREVGDRRSEAIALCRLGAALASVGEVGEARRALEPAERLLAQLGDEPDVELARVASGFVDLALAQAARRAGQGDEAAAHVGAARRRIARAREGSPSSASRSDDVRLLLRILERSLAALGDLAEARAGVERELLLTEGARFVRPPGGGWHDLRERHAARRLLLALAEQQRCAPGRGLSLAALKEAGWPGERILPEAAANRIYVAMNQLRKLGMKPWLRRDAEGYSLDPALPVHYAAVEPGARGGGDSRGGTGEGEGRGGGKRR
>NC_021658.1|WP_148314306.1|11370881_11371520_-|hypothetical-protein
MGSVHRSGRIRLCMKTARALALATGMLGALLCAACAADPEPAPPKISVGAVDGTDAVLAVVRGEGAVTLYVCGGASTYATMTRWFEGPEDPSGAFSIESGGWIATADPGGESGRLRAPDGAELAFRARPAARGSIEGLYAADDGGCRTGAVVFTPEGAESPALQGTWCAVGDRFAQVTPLRPLSALDRRGIQVQVELDGARKNLLVTPLGRP
>NC_021658.1|WP_020739941.1|11371723_11372398_+|hypothetical-protein
MNHRCGVLLVMLACGCSIVDPSDRDELRDQIAAMPPEEISRLRILGMNSAALDWLKGRPPGDQMGKIQCRYQAGGQWTNWADQEPPFIVDDMRDCLIRRPFLVTYVMCMEEWEALQRQERKTNLMNSLPIPGGATVECRFVWDFRYEPEKAPAEVTNPEAVDTDDIINTLIALPAPPPGWAFPRLVPLLCPLGAGPGWGCPPKPADPTGGQPTDPTGGQPGDRP
>NC_021658.1|WP_049949900.1|11372460_11373519_+|hypothetical-protein
MFTTKDPELWKWHLENLAQLCAAAWDDDLHDEDRAWAESYRKKFSRWIGDSGPPGGGHRVNAGPRRSPRGRFDGEPTPPWPMLLEAVQSAFFSMMEASKEMRPDTSERAVEDPMSRLHRTYLWRTLTSEDTAEELRAEALRAFRRGYRIGRRGKPGTLTRAIPPMLDAPAIWKLGAPALPGPSAARERALRALPAPDDPTELMEIEQELRALYTSAWRDDVPDEDRIWAARYRETCTLWVNQHRRGALAQSAYEGYLQSSDGRFGGEPAGPWRSVSAFAKEPWCSFVDRVEDAPEGESEPETAAAAAWEYWDAHCREAPPWDSDPDQAHWLAALRAARRKAQDDDGPPEMGR
>NC_021658.1|WP_148314307.1|11373673_11374066_+|hypothetical-protein
MPSITGLRRWPIREAVDIGIGADVGLFGLGGDARWLGVLGGPAAAIRAMPFRAPLSLELTTRLDFGRIPVCNAWGLCLRYLGLFPAVEAGAAYLSTQHVAIVATCGVRFINTLAWSGVSVEPAAAGRIFW
>NC_021658.1|WP_020739944.1|11374131_11375307_+|hypothetical-protein
MPSIANPKPLVRRSLCEASLGQRLFSTRDPETWTAHFEALGTLCADAWLDDLPEADRAWAAAHRERFRRWIDVPGPNGADPRASASALQSDPVPVPGELTLPWPMLLGAVESAFFASVRVFEVTPAGERERAAADAAARLHRSYLWRTLSSDAAAAPHRPEALRAFQRGFELGRGTPSSSRMPVPPMLEPPWYWGAGLPEYPGPMATRERALRTMSISAGRAEWLSRNRELRALYASAWRGDVPEEDREWAQVVRDCCTTHVNRRRRDAIARTAYEGYLQSSGGLFDGEPGRPWPMLSHTTSEPWRAFAERVEDAPEGESELATAEAAARELWETLYAKFPPWDGDPDQAHWLAALRAARAKALAGDAPPENACCPQETPPGYSAPLQSET
>NC_021658.1|WP_044986651.1|11375276_11375765_-|hypothetical-protein
MHDMSEQLVGALSAVLWVAFGSSASGCVSHPEVSGKVIITRDDEELVLDTGGNGTRVVDASGEVAGGCIVRNQTELSVTVQKEGVAFSFFDLVDQAGLPHVSAEIDGKLYQGACEIIVEERQGDPYEADVAAGPCDLVRLFDGAKARLEMAVFHVSDCSGAE
>NC_021658.1|WP_148314308.1|11375752_11376169_-|hypothetical-protein
MLLFIGVSAGLGCAPDLDCPGSGPHEGDPAVWLWDGTQNEAPGCAEATEVLWEGWRKGSSTAPESPTFARACAGVVREDIPDGYTLCVIPTEVEEICWDGYADHAIYVEEDGEEHVMCCTPAGNPPTVLPQGYGGCTT
>NC_021658.1|WP_044989317.1|11376192_11377554_-|protein-kinase
MVRTFLAQQVGDEGATVWLHLREGQSMDRTAFASELQRLQEIARAVPQLEPVLYGDAGGLSAWVACRRSHGISLKDATRGADLGATALQMVIDVARAIQRCHALGWCHGALGPDRVFITSKRDYSINQFGLVRLFRIEPHEAAREPLVAPPELLRGDRVGPRADVYGLGTLLYELVCRRSLDAGLPGTLGAQRDKPVIPVGTPRAVAAAIEMALEEDPRRRYRNVDHFITVLEGLVEAWPTLDLEPSGDEEMAVVTGGAPSTLRSSHLDAPRSPAPVTEEPDARSSEVEPAASLLNDDEPQHPEIPSLDVPSWTAPEPQELVLSPPPSLVRGPGRAPMMAPSKAADTPPRRLAGRIAVSVAAMAVLCAGVLLTRPARIVLRAEKLSAALVQQVSALPEGRRSPPPPVAEPTPPKKADGRPRVALSRRAGVAARAELRRPYCEAGDVSCGPALY
>NC_021658.1|WP_044986653.1|11377607_11378582_-|hypothetical-protein
MLRSALVIGGSKAAAVAMFLLALPLASAASPPRPPPPPPRSPRVAALVREAEAAFDRLEIARARHLWAQIYELERSTVAICQLGQLDRRLERWVDAAGELTRCVQEMRPPATPMERRLHDTRHADLAAARRQVTELRVFAPAGAAPVLVDGRIVDESGRIYVEPGQHEVTAALPDGRKARSTVRVTAGDARAVLLSPEPARLRPAAPPPARPAGAPAQPAAPPAPWLLYAGSAASGAFLVSGIVLHVVASLQDSALQAEMCKPRSTGNPKLLEELHAVEVQQHISTAALVAGTALGAATLVVAMLPSGAQIRAHGAGAEVRFSW

Crispr_ID: NC_021658_53

• CRISPR_ID: NC_021658_53
• CRISPR_location: 11465309-11465423
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_53

Consensus_repeat	Method
CCCGAGGGGAAGCGCGGCGGCCCCTCGC	CRISPRCasFinder

spacers of NC_021658_53

>53.1|11465337|59|NC_021658|CRISPRCasFinder
GGGGCGGCTCGCGGGTCGCCGCGACCGCCCGCGCGAGCGCCTCCGCGGTCGGCGCCGCG

CRISPR arrays and Neighbor proteins around NC_021658_53

CRISPR arrays

The CRISPR arrays of NC_021658_53

>merge|NC_021658|53|11465309-11465423|CRISPRCasFinder
CCCGAGGGGAAGCGCGGCGGCCCCTCGCGGGGCGGCTCGCGGGTCGCCGCGACCGCCCGCGCGAGCGCCTCCGCGGTCGGCGCCGCGCCCGAGGGGAAGCGCGGCGGCCCCTCGC

>NC_021658|53|46|11465309-11465423|CRISPRCasFinder
CCCGAGGGGAAGCGCGGCGGCCCCTCGC	GGGGCGGCTCGCGGGTCGCCGCGACCGCCCGCGCGAGCGCCTCCGCGGTCGGCGCCGCG
CCCGAGGGGAAGCGCGGCGGCCCCTCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_049949759.1|11474004_11475507_+|replicative-DNA-helicase	unknown	unknown	gnl|CDD|273206
NC_021658.1|WP_020740015.1|11459734_11460019_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020740011.1|11454514_11456134_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020740022.1|11470417_11471089_+|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|235457
NC_021658.1|WP_012239546.1|11471743_11472064_+|30S-ribosomal-protein-S18	unknown	unknown	gnl|CDD|178997
NC_021658.1|WP_020740017.1|11461286_11462711_+|thioredoxin-family-protein	unknown	unknown	gnl|CDD|234717
NC_021658.1|WP_148315001.1|11475731_11476118_+|hypothetical-protein	unknown	unknown	gnl|CDD|274527
NC_021658.1|WP_148315000.1|11467243_11468179_-|riboflavin-biosynthesis-protein-RibF	unknown	unknown	gnl|CDD|235536
NC_021658.1|WP_020740008.1|11451797_11453492_+|ATP-binding-protein	unknown	unknown	gnl|CDD|223510
NC_021658.1|WP_148314313.1|11458046_11459162_-|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NC_021658.1|WP_020740018.1|11462727_11463660_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020740009.1|11453534_11454131_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_021658.1|WP_044986676.1|11463669_11464677_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_020740024.1|11472074_11472527_+|50S-ribosomal-protein-L9	unknown	unknown	gnl|CDD|234659
NC_021658.1|WP_044989328.1|11468433_11469378_+|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl|CDD|234929
NC_021658.1|WP_020740021.1|11469592_11470279_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl|CDD|235534
NC_021658.1|WP_148314999.1|11456326_11457925_-|DUF2254-domain-containing-protein	unknown	unknown	gnl|CDD|378351
NC_021658.1|WP_061628018.1|11460586_11461222_+|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NC_021658.1|WP_020740023.1|11471201_11471741_+|30S-ribosomal-protein-S6	unknown	unknown	gnl|CDD|275385
NC_021658.1|WP_148314314.1|11472602_11473583_-|sugar-kinase	unknown	unknown	gnl|CDD|238572

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_049949759.1|11474004_11475507_+|replicative-DNA-helicase	gnl|CDD|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_021658.1|WP_148315001.1|11475731_11476118_+|hypothetical-protein	gnl|CDD|274527	TIGR03340, phn_DUF6, phosphonate utilization associated putative membrane protein. This family of hydrophobic proteins has some homology to families of integral membrane proteins such as (pfam00892) and may be a permease. It occurs in the vicinity of various types of operons for the catabolism of phosphonates in Vibrio, Pseudomonas, Polaromonas and Thiomicrospira.	0.00623962
NC_021658.1|WP_020740011.1|11454514_11456134_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.02533e-78
NC_021658.1|WP_020740022.1|11470417_11471089_+|aminoacyl-tRNA-hydrolase	gnl|CDD|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	8.42427e-97
NC_021658.1|WP_012239546.1|11471743_11472064_+|30S-ribosomal-protein-S18	gnl|CDD|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	2.56877e-37
NC_021658.1|WP_020740017.1|11461286_11462711_+|thioredoxin-family-protein	gnl|CDD|234717	PRK00293, dipZ, thiol:disulfide interchange protein precursor; Provisional.	1.80526e-67
NC_021658.1|WP_148315000.1|11467243_11468179_-|riboflavin-biosynthesis-protein-RibF	gnl|CDD|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	1.44491e-109
NC_021658.1|WP_020740008.1|11451797_11453492_+|ATP-binding-protein	gnl|CDD|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	1.57281e-10
NC_021658.1|WP_148314313.1|11458046_11459162_-|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	3.67842e-13
NC_021658.1|WP_020740021.1|11469592_11470279_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl|CDD|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	1.10773e-70
NC_021658.1|WP_020740009.1|11453534_11454131_+|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	3.66137e-29
NC_021658.1|WP_044986676.1|11463669_11464677_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	3.54642e-08
NC_021658.1|WP_020740024.1|11472074_11472527_+|50S-ribosomal-protein-L9	gnl|CDD|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	3.2207e-58
NC_021658.1|WP_044989328.1|11468433_11469378_+|ribose-phosphate-pyrophosphokinase	gnl|CDD|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NC_021658.1|WP_148314999.1|11456326_11457925_-|DUF2254-domain-containing-protein	gnl|CDD|378351	pfam10011, DUF2254, Predicted membrane protein (DUF2254). Members of this family of bacterial proteins comprises various hypothetical and putative membrane proteins. Their exact function, has not, as yet, been defined.	3.12663e-16
NC_021658.1|WP_061628018.1|11460586_11461222_+|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.52305e-06
NC_021658.1|WP_020740023.1|11471201_11471741_+|30S-ribosomal-protein-S6	gnl|CDD|275385	cd00473, bS6, Bacterial ribosomal protein S6. bS6 is one of the components of the small subunit of the prokaryotic ribosome, a ribonucleoprotein organelle that decodes the genetic information in messenger RNA and forms peptide bonds to synthesize the corresponding polypeptides. Ribosomes consist of a large and a small subunit, which assemble during the initiation stage of protein synthesis. Prokaryotic ribosomes consist of three molecules of RNA and more than 50 proteins. The small subunits of bacterial and eukaryotic ribosomes have the same overall shapes (with structural elements described as head, body, platform, beak and shoulder). The bacterial ribosomal protein S6 is important for the assembly of the central domain of the small subunit via heterodimerization with ribosomal protein S18.	9.59982e-28
NC_021658.1|WP_148314314.1|11472602_11473583_-|sugar-kinase	gnl|CDD|238572	cd01167, bac_FRK, Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.	5.35671e-44

Protein sequences

>NC_021658.1|WP_044986676.1|11463669_11464677_-|hypothetical-protein
MQPNHRSLATPVLSLLGALACALSAPEARAELPFDDEPTALDPRVDRLDAAPHELWAPSPGRAQPLWISLQLGLARLEGGERSLSGMLLASIPLERLSDRPGVPPPSAIAEPEAPRLKPAPPSPPRAAPAPGPPRAAPAPDPAEAPPAPPPAPPPAEVEPPLPLPVRVTPAMARAIVEAALRQSRLLDPEARIDAIASRARTSSLLPELRLRVSRLVDEAENLAPTEYDPARRTASGGTSLWLEARATWRLDRVVFADEEIALERLRRERAELQAKLTARVLELLFAWQRAVALSADPGRSPEERRAAALAALEAEASLDLLTGGRMTRWRAARE
>NC_021658.1|WP_020740018.1|11462727_11463660_+|hypothetical-protein
MRPSLLAALALCFLILAGCGGAPRPLTGTVVIGLTSELRAGVELDRLRMVLRAGGEVLRDDVLTHKSGQLFFPRELFFRDLEDGTAVEISLEAFGAEDAERPVLVRAASTRVIGGRELLLRVRLEQECAVAPGDPTCPAPQTCVAGGCSAPDVDPRRLEPYSASWSADAVPDACKPAGGGEPVVVVGEGQADYFALEDLDEVQVEAGPQGGYHIFVAIRLKNLRQSGSITVVNGAVPELGYTVEPLRVIFTLDQDEGGFCKLAGLRFRLDGERTIDELLGKVVDVEVTVTDADGDTGTGRRKVTLSQTIL
>NC_021658.1|WP_020740017.1|11461286_11462711_+|thioredoxin-family-protein
MTASTRFKGSAGAAPAVRRRGAGGAAGALGRALAALAVLAVLASPALALAADQPDLFTRGLQAGPAFAGLAALAGGLLTCLTPCVYPMIAITVSIFGAREAKSRREAMLLSTSFVLGIVVLFTTMLVVAALTGSLFGSVLANRWVIVGIAGVFIAMSLSMFGAFDMALPEPLMQRLSQVGGIGYGGAFLLGLVSGLVAAPCTGPVLTGIILWIGKTQSIGLGALVGATFALGLGLPFWLVGAFAVALPKGGKWMLGVKSFFGIVMLIVALYFLKTTFPALSSLAQPTPQFMAVMAGLVVVGVLLGAVHLSWDDGGVGVKARKGLGIALTVTSGFLLVASLDLPRLASPVPSAVAGEAAPRQLTWLHQEPVAVSKAKAEKRPLLVDFTAEWCGACKQLDKDTFSDPRVMAKAAHFVAVKVDATDDEDPQVDAVKGKYKVVGLPTVVIYDSTGAERKRFNDFVGPDVFLAALEGIE
>NC_021658.1|WP_061628018.1|11460586_11461222_+|hypothetical-protein
MSLRGPLDRTTQAMLLRQLYLAYFETRRFERAAEVAEQVLSLGVLRDVAHQDAARAKQALGDIDGAVGHLRLAARTGPASRRAFHWWTLGSVYHLARRYDEAIGALTRAARWGTRDKPLYQGHLAVVQCESGKTVEGLGALIDRLSEVPAGQGYGRFVLGQMAYFDRRWDEAKKYLEAFVQRSTSGRAAVAIALGGEIEAARQTLASLPKR
>NC_021658.1|WP_020740015.1|11459734_11460019_-|hypothetical-protein
MSCLALVGGASLAAGCGHPASRDECEAIFKRSAEIELRAQNVVDPKVVEERTAAVRDARGKELIDRCVGRRITDAAMACVRQATTPEQVDRCLE
>NC_021658.1|WP_148314313.1|11458046_11459162_-|hypothetical-protein
MKAPSPLLGFNNNVRHKGRLFHIQTEDSGIRHPHIITHLFADGGRILKTTKTSYAEHVGQASLAETVRGMMKEQHKAMFIALRDGHFDYLFDDSAAPPVSAPAAAAPAAVDPSKAARPPAPSSPEVPSAPKPPPPSRPLALPVASPVVPPLAPEAAPRPKPAPAPTPPPRPAAPPARPAPAPAAAPPARAAAPEPAPAPASARPRLELDPVGIQGLGGGGRAASPLTGRAVRPPPEIKKSEPSIDLDLDALERAAAEAQTPFFQQIQDLPPPPASVIGRRSESAASGAGVYSNVHPEHPSPPPAAPVAVEHFSGSPGSGRYAASRPASIFATNRPSDGASIFGDDLISEKSLDEVILSYLAEDLDSPPEKK
>NC_021658.1|WP_148314999.1|11456326_11457925_-|DUF2254-domain-containing-protein
MARIWLRPMSYLLGVSMATLSVVYLLDIARHGNERLPIREALLHMSPSDAEHIMGGIGEVIAAILGIVITVASIIVQLAANRYTPRITEMFFRDRTNMVVMGFFVVSAVFSLWVNFSIRVGEGSTEHAFVPTYGVLVTMGLLTASLLMMAPYFLYVFDFVEPDNVVGRIKRSGIEQALRPADHESDGEVDERRVTALSSLEQLADVALNAIDQKDKGIASKTVDSLSELVVAYLPHKATLDPRWFQIRDRLANDADFVSMNAEALGKLSATRTWLEYKALRQFLMVYREALTAMPDLITRIAIDTRYIGQTAIAAGDRAAVAVVVKFFNTYMRRSLNAKDIAAAYNNLNQYRYLAEELLKAGWGDQVLDIARYFKYYAQTAHAMGLAFLTETVAFDLCVVNERAYDLHAPARDELLQLFLEVDKEAELDQQEPSLRGVRKAQVKLATYYLQKGEEALARRIYRDMRDERPDRLRSIRAELLAVTSNEFWEINDRGAVFEYIEPERRQLIHRFFEWFPSTTMREPIREEHTQE
>NC_021658.1|WP_020740011.1|11454514_11456134_-|serine/threonine-protein-kinase
MPASRPRRKHAESDPPPELFAGKYRLVRMLGKGGMGEVWLAEQEQPPSSRRRVALKRLAPRPELGEAARESFFAEAEVIARLDHPNVVRLIELGDCEGSVYLALDYIDGPAVDRVLRKVGALSPRAVAYLGREMARALEAVHSLREADGRRYAVVHRDVSPSNILIARDGRVCLTDFGVARIPGLAGEQADGAVFKGKLPYMPPELARGEPFDGRADVFSLGLTLLEALLGSRVRKADTQAQLIMRVASTPVPRARELLPDLCAPLADALDAATEFRADKRIASAGELAEALEQVLRGMGHGAEDEARSELKEHVEAYIARAGSLSGAGCHASPSLPPASGPGQSSPDLLGRAQSGVPGAASGDRPSGRPSAPDARRSAPSLRRSGAPRPLGAAVGSLSVQYLDFDGPEDTPPRPRALAASTTPEGELQRSRAAAEAPGGAAAAQKTGRASAAGRASAASVAGKASAPAGASAASAPAGTSSLAGVSAGRGSGEIAPGEPPESGGLTDEQLRRKRRIFLAGLFVLGAIATIRLVVVSSC
>NC_021658.1|WP_020740009.1|11453534_11454131_+|Uma2-family-endonuclease
MSGVAKKLASKPATLEDLLAIPEADRRHEIVDGELLEKGAATGEHGGAQADLVTALNHRFGRRPGGRWPGGWWFATEVEISFAPAQVYRPDVVGWRRERAPQRPTGVPITLLPDWICEILSTNRRNDLVKKKRTYHRCQVPHSWIVDPAEETLAVHRWGPDGYIEILAAQRGEIVRAEPFDAIAFHVGVLFGDDEPEE
>NC_021658.1|WP_020740008.1|11451797_11453492_+|ATP-binding-protein
MPPARLARPAALAYSPPASATSPEPHGGDPLSPILSLCHGYRLDLSDYARTGLRVGIWASSGRGKSFGVGVFCEELLAAGIPVVAIDPEGELHTLRERFRALVLGGAHADLPLSSRERAAELALARVLDEGLGLVVDLSDQPTSRAQQEAALPFLERLWALLSERRAPAAVVVEEVHLFAPQSGASLTSEILHRLAKQGRKRGVLLVVASQRTQAVSKELMSQLNFPAIGGFEIERDYDAVKALVDGHPFEEFRALPSGEFYLPAVGRFERWRARHTAHGGDAPSWTGEAGGAPRIADAALSTLIDELRAALAGEIARPAAPDPSAALRTEIRRLKQQLEQADEARRAAEAEAERLRTALQVAGIVKVVIQNEIVARAGQSDGARPQAAHGPGALAAHVPGAPAPHVPGAPAAHVPGALAAPIPGAPRSHLPASPAAPLAPASGGAAVKVAARPSSPSLRDLAMPPAALLQARGVQRMVSAARSHARRRSPRSGAHVALAAKLLAGGAALTAEELAARGGSRSQVEIRRAARALAALAHAGFASVQGGRHALNEAAVLRALQIG
>NC_021658.1|WP_148315000.1|11467243_11468179_-|riboflavin-biosynthesis-protein-RibF
MVIIGNFDGVHRGHQALLADAALDAERRGLSPVALTFAPHPASVLGRTPPPTLTALPRKIELIRRVQPAIRVEVVTFDRAFAAQTPEEFVRRVLLDRLAARVVLVGANFRFGHGRAGDFTTLGRLGEDLGFETRSHPLVGDAEGAWSSTRVRAAIARGDLEAAEQMLSRPHMLSGVVAQGAKRGRTIGFPTCNLDEIEEALPPFGVYATLVDRVTPSGRAIALARGVANLGVRPTVEPSKQARPNLEVHLFDIDEDLYGAALRVHLVARLREERRFSGLPELKAQIARDAEAARARLAPLAPDPAAEGAFR
>NC_021658.1|WP_044989328.1|11468433_11469378_+|ribose-phosphate-pyrophosphokinase
MFKRVSIFSGNANFALTQEICQVLEQPMGKSRVSRFSDGETFCVIQENVRGVDTYVVQPTCSPVNDSVMELLIMVDALRRASAGSITAVIPYYGYARQDRKVAPRTPITSKLVADLIVAAGVNRIVALDLHAGQIQGFFNIPFDHLYAMPALLDHHLREHYGKDVVIVSPDAGGVERARAYSKRLQGTLAIIDKRRERANESEVMNIIGEVAGKQCLILDDLIDTAGTLVNAANALMKQGARSVAACATHPVLSGPAVERIKDSPLTEVVVTNSIPLSDEARASGKFKVVSVARLLAEAIRRIHHSDSVSSLFV
>NC_021658.1|WP_020740021.1|11469592_11470279_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MEIIKLNATRREESGKSASSRLRRAGQIPAIAYGRELAPLSVAVSPKALLQVLGSDHGKNSVVELAIENGETLTVMVRDYDYHPISRELVHADFIQVKLDQPVDVHIPFRTVGKPKGVVTGGVLQQIFRTIPVRCLPEKIPSFIEIDVTELDMGESFKASGLTLPEGVKALLADDQTIAVVNAPEKAGAEEEAKPAAGAPAAAAAPAGGAAAPAKGGAAPAGDKKDKK
>NC_021658.1|WP_020740022.1|11470417_11471089_+|aminoacyl-tRNA-hydrolase
MLLVVGLGNPGKEYAAHRHNVGFMAIDALADEVRADPFREKFSGVHAKAEIAGQPAILLKPMTYMNESGRSVQPAMAFFKVAPSSLIVLHDELDLPFGTVRLKVGGGHAGHNGLRSIIAHCGTGNFGRVRLGIGRPPPGYRGEVAGYVLSGFDAVERAGLPDCLKQAVQSVLEVAARGFDAAMNVRNTRPKPGKRQKGEGDGPTDPAPAAKGERGPLPPTQKP
>NC_021658.1|WP_020740023.1|11471201_11471741_+|30S-ribosomal-protein-S6
MSRQVTAPGRAKEYETIYILRPDIDADGAERIGTRLAEVVTREAGRLTKVETWGRRRLAYDIAKHRRGVYVYLKYLGGGKVVSEIERNLRLADGVLKYQTVLVRNDVEVQGLTVADEDVKFERLELTPIEDDRDDSRERQLGLIEPERRVDRSSEAAPAGDLDEAEEGEAEGAADEEES
>NC_021658.1|WP_012239546.1|11471743_11472064_+|30S-ribosomal-protein-S18
MNGRNNDMGRNGGADYDDRDFGRTPDLNADAPGRRRTGRKRVCRYCADKALVIDYKDPQALKYFISERGKVVPRRISGNCARHQRKVTLSIKRARNIALLPFTVTA
>NC_021658.1|WP_020740024.1|11472074_11472527_+|50S-ribosomal-protein-L9
MATHIHVVLTEDLHNVGKSGELVKVRPGFARNYLIPRGLAVGATAENVSRIEHEKRVAESRAAKTRSEAEQLAAKLNQVKLTITRPVGEGDKLYGSVTARDIEEALAAQGFSVDRRRIESDTIKTLGAHTVTLRLAPSITASVEVTVAAK
>NC_021658.1|WP_148314314.1|11472602_11473583_-|sugar-kinase
MDHKTRQTRIEPTEVICVGEALWDLYAPEGIPLEQAKLLRRVPGGGAVNTAMALARLGVPSGVCAALGDDALGRGLRDEVAAAGVDVGRLALGAARTGLMLVAIARGEARFAGYRQGELEARELAAALPARWQARVVHFTGIAPVRGAIGAIARAAAAARREGCAVSIDVNARPRMWPRAGRAAAPARVGAGAAAPAGAGAGAGDGVRGCFRLFAQADLVKCSTGDLEVLGTTARALRERLRPEATLVVTDGARATLVLGPEGERAVAPRPVRPLDPTGAGDAFCAGMLASLAWEARARWADPALMLRAVARGHDVARAWVRRKRG
>NC_021658.1|WP_049949759.1|11474004_11475507_+|replicative-DNA-helicase
MMRMMERRGQRPQRIEPPIVAGRVPPHDLDAEAAVLSAILLHRDALDRVLEILKSEHFYSEANSRIYEAAQELASGGTPIDIVSVASWLRDRERLAQVGGAAYLAQLADATPAVAHVGAHARVVYEKWRVRQLIATCQRVAAEGYGDVGVVQQFIDGAEQAVYQLARTPQGTSTQPIAQVLKAAFEQITAAAERGDRITGISTGFEKLDAKTAGLHDGDLSIVAARPGMGKTSFVLNLAVNVASPRTVSSPGPDQAGHGIERHEPGFGAAVFSLEMPREQLATRMVCSEGRVDVGKLRQGFLQPDDWRRLTEAASFLSTLPIWIDDTPAISLLELRAKVRRIQAEYDRPPSDGNSGRRVGLVVIDYLQLMKGRDGVSSREQEISEISRGLKQLAKELKVAVIALSQLNRAVETRTTKDKRPQLSDLRESGAIEQDADNIIFIYRDEYYNPETTNHKGIAELIVAKQRNGPTGKVLTRFTSSCTRFDNLAPGDYPDMVDDE
>NC_021658.1|WP_148315001.1|11475731_11476118_+|hypothetical-protein
MAGHYLMLRAAAGRVGDALGALCIEATAAAGILVFLLLRPGTEAPPTAQGVIWACASGLFISGVTTLVFTALRLGGPVSATGPMVFAGGVALAALFAPLLFGEAFTARRALGVCLGIASLVVLATERS

Crispr_ID: NC_021658_54

• CRISPR_ID: NC_021658_54
• CRISPR_location: 11531270-11531382
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_54

Consensus_repeat	Method
GCGTCTGCTCGTTGTTCGACGCGAAGC	CRISPRCasFinder

spacers of NC_021658_54

>54.1|11531297|59|NC_021658|CRISPRCasFinder
CCGTGCTGCCCAGGTGGTCCGGGTGGTAGTAGATCGTCGGCGGGTCCCGGAACCAGTCC

CRISPR arrays and Neighbor proteins around NC_021658_54

CRISPR arrays

The CRISPR arrays of NC_021658_54

>merge|NC_021658|54|11531270-11531382|CRISPRCasFinder
GCGTCTGCTCGTTGTTCGACGCGAAGCCCGTGCTGCCCAGGTGGTCCGGGTGGTAGTAGATCGTCGGCGGGTCCCGGAACCAGTCCGCGTCTGCTCGTCGTTCGACGCGAAGC

>NC_021658|54|47|11531270-11531382|CRISPRCasFinder
GCGTCTGCTCGTTGTTCGACGCGAAGC	CCGTGCTGCCCAGGTGGTCCGGGTGGTAGTAGATCGTCGGCGGGTCCCGGAACCAGTCC
GCGTCTGCTCGTCGTTCGACGCGAAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020740074.1|11560963_11562670_+|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NC_021658.1|WP_020740064.1|11529786_11530392_-|5-formyltetrahydrofolate-cyclo-ligase	unknown	unknown	gnl|CDD|274270
NC_021658.1|WP_148314317.1|11521183_11523061_+|PEGA-domain-containing-protein	unknown	unknown	gnl|CDD|285503
NC_021658.1|WP_020740072.1|11553883_11555875_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_021658.1|WP_020740059.1|11517295_11518480_+|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|173838
NC_021658.1|WP_187345747.1|11548185_11549586_-|PEGA-domain-containing-protein	unknown	unknown	gnl|CDD|285503
NC_021658.1|WP_020740065.1|11530733_11531183_+|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl|CDD|234795
NC_021658.1|WP_020740058.1|11516650_11517208_+|Fis-family-transcriptional-regulator	unknown	unknown	gnl|CDD|349400
NC_021658.1|WP_020740062.1|11526251_11526428_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020740063.1|11526582_11526912_+|PilZ-domain-containing-protein	unknown	unknown	gnl|CDD|377796
NC_021658.1|WP_020740071.1|11550170_11553887_-|hypothetical-protein	unknown	unknown	gnl|CDD|238121
NC_021658.1|WP_148314320.1|11544811_11548186_-|VCBS-repeat-containing-protein	unknown	unknown	gnl|CDD|379232
NC_021658.1|WP_044986682.1|11527235_11529776_-|hypothetical-protein	unknown	unknown	gnl|CDD|225743
NC_021658.1|WP_148314322.1|11558069_11560490_+|VCBS-repeat-containing-protein	unknown	unknown	gnl|CDD|379232
NC_021658.1|WP_020740060.1|11518631_11520686_+|M3-family-metallopeptidase	unknown	unknown	gnl|CDD|341051
NC_021658.1|WP_148314321.1|11549682_11550114_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187345746.1|11540354_11542775_-|hypothetical-protein	unknown	unknown	gnl|CDD|377060
NC_021658.1|WP_148314318.1|11523198_11525094_-|hypothetical-protein	unknown	unknown	gnl|CDD|275079
NC_021658.1|WP_187345748.1|11556129_11557659_+|PEGA-domain-containing-protein	unknown	unknown	gnl|CDD|285503
NC_021658.1|WP_020740067.1|11543302_11544109_+|hypothetical-protein	unknown	unknown	gnl|CDD|176962

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020740074.1|11560963_11562670_+|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	2.82505e-72
NC_021658.1|WP_020740064.1|11529786_11530392_-|5-formyltetrahydrofolate-cyclo-ligase	gnl|CDD|274270	TIGR02727, Uncharacterized_protein_YqgN, 5,10-methenyltetrahydrofolate synthetase. This enzyme, 5,10-methenyltetrahydrofolate synthetase, is also called 5-formyltetrahydrofolate cycloligase. Function of bacterial proteins in this family was inferred originally from the known activity of eukaryotic homologs. Recently, activity was shown explicitly for the member from Mycoplasma pneumonia. Members of this family from alpha- and gamma-proteobacteria, designated ygfA, are often found in an operon with 6S structural RNA, and show a similar pattern of high expression during stationary phase. The function may be to deplete folate to slow 1-carbon biosynthetic metabolism. [Central intermediary metabolism, One-carbon metabolism].	4.44358e-44
NC_021658.1|WP_148314317.1|11521183_11523061_+|PEGA-domain-containing-protein	gnl|CDD|285503	pfam08308, PEGA, PEGA domain. This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteristic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	7.66135e-05
NC_021658.1|WP_020740059.1|11517295_11518480_+|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	4.76572e-63
NC_021658.1|WP_187345747.1|11548185_11549586_-|PEGA-domain-containing-protein	gnl|CDD|285503	pfam08308, PEGA, PEGA domain. This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteristic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	2.38e-09
NC_021658.1|WP_020740065.1|11530733_11531183_+|large-conductance-mechanosensitive-channel-protein-MscL	gnl|CDD|234795	PRK00567, mscL, large-conductance mechanosensitive channel protein MscL.	7.6144e-52
NC_021658.1|WP_020740058.1|11516650_11517208_+|Fis-family-transcriptional-regulator	gnl|CDD|349400	cd05381, CAP_PR-1, CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain of pathogenesis-related protein 1 (PR-1) family proteins. Members of pathogenesis-related protein 1 (PR-1) family are among the most abundantly produced proteins in plants on pathogen attack. They are considered hallmarks of hypersensitive response/defense pathways and may act as anti-fungal agents or be involved in cell wall loosening.	1.41118e-49
NC_021658.1|WP_020740072.1|11553883_11555875_-|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	4.22863e-08
NC_021658.1|WP_020740063.1|11526582_11526912_+|PilZ-domain-containing-protein	gnl|CDD|377796	pfam07238, PilZ, PilZ domain. PilZ is a c-di-GMP binding domain which is found C terminal to pfam07317. Proteins which contain PilZ are known to interact with the flagellar switch-complex proteins FliG and FliM. This interaction results in a reduction of torque generation and induces CCW motor bias. This domain forms a beta barrel structure.	7.2155e-05
NC_021658.1|WP_020740071.1|11550170_11553887_-|hypothetical-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.82285e-67
NC_021658.1|WP_148314320.1|11544811_11548186_-|VCBS-repeat-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	3.78243e-12
NC_021658.1|WP_044986682.1|11527235_11529776_-|hypothetical-protein	gnl|CDD|225743	COG3202, COG3202, ATP/ADP translocase [Energy production and conversion].	1.07596e-11
NC_021658.1|WP_148314322.1|11558069_11560490_+|VCBS-repeat-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	5.23392e-11
NC_021658.1|WP_020740060.1|11518631_11520686_+|M3-family-metallopeptidase	gnl|CDD|341051	cd06456, M3A_DCP, Peptidase family M3, dipeptidyl carboxypeptidase (DCP). Peptidase family M3 dipeptidyl carboxypeptidase (DCP; Dcp II; peptidyl dipeptidase; EC 3.4.15.5). This metal-binding M3A family also includes oligopeptidase A (OpdA; EC 3.4.24.70). DCP cleaves dipeptides off the C-termini of various peptides and proteins, the smallest substrate being N-blocked tripeptides and unblocked tetrapeptides. DCP from Escherichia coli is inhibited by the anti-hypertensive drug captopril, an inhibitor of the mammalian angiotensin converting enzyme (ACE, also called peptidyl dipeptidase A). OpdA may play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. It can also cleave N-acetyl-L-Ala. This family also includes Arabidopsis thaliana organellar oligopeptidase OOP (At5g65620), which plays a role in targeting peptide degradation in mitochondria and chloroplasts; it degrades peptide substrates that are between 8 to 23 amino acid residues, and shows a weak preference for hydrophobic residues (F/L) at the P1 position.	0
NC_021658.1|WP_187345746.1|11540354_11542775_-|hypothetical-protein	gnl|CDD|377060	pfam03534, SpvB, Salmonella virulence plasmid 65kDa B protein.	5.33133e-10
NC_021658.1|WP_148314318.1|11523198_11525094_-|hypothetical-protein	gnl|CDD|275079	TIGR04247, nitrous_oxide_maturation_protein_NosD, nitrous oxide reductase family maturation protein NosD. Members of this family include NosD, a repetitive periplasmic protein required for the maturation of the copper-containing enzyme nitrous-oxide reductase. NosD appears to be part of a complex with NosF (an ABC transporter family ATP-binding protein) and NosY (a six-helix transmembrane protein in the ABC-2 permease family). However, NosDFY-like complexes appear to occur also in species whose copper requiring enzymes are something other than nitrous-oxide reductase.	1.19341e-06
NC_021658.1|WP_187345748.1|11556129_11557659_+|PEGA-domain-containing-protein	gnl|CDD|285503	pfam08308, PEGA, PEGA domain. This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteristic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	1.12624e-08
NC_021658.1|WP_020740067.1|11543302_11544109_+|hypothetical-protein	gnl|CDD|176962	CHL00019, atpF, ATP synthase CF0 B subunit.	0.00755792

Protein sequences

>NC_021658.1|WP_020740065.1|11530733_11531183_+|large-conductance-mechanosensitive-channel-protein-MscL
MFWDDFKKFAIRGNVVDMAVGVVIGAAFGNIVKSLVDHLIMPPIGLVTGGIDFSRHYIVLKAPSGPGPYATPDEMVKAGAVLLQYGQVINNLVSFFIVALSVFLLMQLMGKLQRKQEEAATTKDCPECAMSIPIKAVRCGHCTAALKAA
>NC_021658.1|WP_020740064.1|11529786_11530392_-|5-formyltetrahydrofolate-cyclo-ligase
MDPDTEAALRYRAKAELRKRARAVRSSIPRDAILERSRRIVRALAELPAVVAARRVALFYPIEDRNEVDLRELDPLLRARGVQVAYPAIDPESRAMTFRFVADPEAMQERGLGFREPDPADEEAAALDVIVVPALQIDARGHRIGYGAGYYDSTLPRFCPPAHAVGVAFDFQLIAEVPATDGDVPLGTLVTDARVLDAEPA
>NC_021658.1|WP_044986682.1|11527235_11529776_-|hypothetical-protein
MPSGPLPENQVEGETDSARPVLIAALASGAMIAQQVAGRATRDALFLSAFGAADVPKVMAAGAVLSFAAVLLLSRALLQLSPARVVPATCAASSALLGLEWALALRAPGAAALVFYLHVAVFGATLISAFWSLVNERFDPHTARHSMGRIAGGGTLGGVIGGVFAWRAGHLVDAPTMLLALAGLSGLAALATYLLGAGLPGATAAGAEGHAEHHAGAAAASSTAASAAASPSGLRALRESPHLRDLALLVGLGAVSGALFDVALSAEAAHAMRDRNELLSFFALFHLSVSLLSFLVQSLAATFSLDRLGLAATIGILPAAVLTSSLSVVVAPRLWSASIVRATEAVLRNSLFRSGYELLYTPLPPDQKRSIKTLIDVGFDRIGTAVGSGLAMVLLALAPDASLPLLIGLGTAAAGVTLLFTPRLHRGYVAALEGSLRSGAVSLDPANVVDATTRRTLSGTVDALSRDKVLAELAALRRGTAARADAGRAHGDGERISYAGPPISARPPVSAGAPGDGPRAPAGERKIAEGPLSARSASAALSSDPVLAAVAALRSGEPERVRRALAPLAREPDPALIPHLLPLLERDGLISEAIRALRAVAPRATGQLLDALLDPAVSLAVRRRIPRVLQACPTQRAADGLMLGLADERFEVRYQCGVALARLLQQRAPIHLRRDDVIAAATREIEIDRRVWDAQPPNASPPAEAPLAERLLVERTSRSLEHVFRVLSLCLEREPLEIAYRALHADDAHLRGTALEYLENVLPAPIRERLWPYLGARPAAPAEPLTAAEPHAGEPGAAAPAAAGPRPAEPRVARLPEQALDELRRSAAKWPRTSISAARRRREPRT
>NC_021658.1|WP_020740063.1|11526582_11526912_+|PilZ-domain-containing-protein
MDRRQGARAQVDFPVSALVDGHRHRCRAIDLSPTGMVVERTPGLAGRALPAVTPFELDLGVGRPIRLRARPVWDRDNLLAVRFVVMSDADRLTIAEHLDERARRREPLH
>NC_021658.1|WP_020740062.1|11526251_11526428_-|hypothetical-protein
MPTCRECDSEVDELKTIKVGTKKKKVCEDCADRAAQEGAIAEESEAVVQQMMGFKGRR
>NC_021658.1|WP_148314318.1|11523198_11525094_-|hypothetical-protein
MHSISQGFGSRSFAAGKFIASLMAMSIVGSGCAPLDEDVSAEDWGAEEQAAGTTFLVGPTRTYKTLNDVAGLLKPGDIVEVDGNVTYPGNIRITRGGTASAKITIRGKRVSGKRPILKGGTNTIELNANHVVLEGFDVTGGTTRCVFHHGHEVTIRDTVVHDCPAHGILGADGDSGSLTLEYVEVYKCGNGTQKHSIYMATDESAYPGAVFRMKHSYVHDTNGGNAVKSRAERNEIYYNWIEGGLYKDLELIGPDGQDPGLAREDSDVVGNVFRKTHTQYVVRVGGDGTGDTKGRYRFVNNTFLLMQGSNAAIHLFDGIESIELHNNVFHRVGGGGVQVFRDTEAKWATGSPVIKGVNNAVPAGSVVPSAFVNTQIVNNPGFTSLDRRDVSLLSSSPLLNKGVSQISGIPGYPFPKPLTSPLFHPPKGAIEAVGTARQRTAVGAMDIGAFEFGSGTTTPSEPTTPTEPTEPEPTTPDPAPSCPTVDAGEWVNTPLTTQWGTFTASWDVTPSAAKIDGVVGLSSGAADQWTELAAIVIFDEQGNVRVRNGSRYEAATVFPYVAGKTYTVRMVVETSSRRYSVYIQPKGGAEVQLAYRYAFRTEQAQIRSLNNWAITQTVGSASLSACNFSMK
>NC_021658.1|WP_148314317.1|11521183_11523061_+|PEGA-domain-containing-protein
MRRLGFMMTTSCALALAACAQGTSTDEPFVDEVGQALVNPASVLGFESTADWTASGGVKSASADHSEGTSALALRNFNFAELQSVPLTTVSGVTSTIAFDLKPPVSPGFGNAQLVVNIPSQGVHSVWLGQVNLAGLPAGTYSPISFNVPASVVSALSNTYSDLTFKIVLNVPQTTTDYVVDNLRFVGGAPAGPSKVELRVSSADDRLVLYVNGLQRRMFDIDDPSIGQRIDVSDWFGSGDNDLRIQTLNTEGSTSYGVEVWVDDQLVVNATCPATLCNGQEVRQGIVADLTYSVDTPNRPAYQPVTVTATSAQPGKVYVNDVYTGRSTPTTLSLPPGNYTIGVGLGTQSPPYDYTGSYREQSVVVGASPMTVDVTANPPLGIQEDTRIGILPIRTSINYSASLGGADPSNVGVLSEDDIERLLTQARATSARWLEPLSYGLAKWTVDVLPPVEDVPIYEPNHDGWDTGRFQSEHPTAHLLSDYDMIVLFIPQHRADGSLVDDESNLAWAWDDRYLAIPTTYTGEGIGVPNAGLLHEVMHNYEGYNRNVLRSYNGIHGLHGSSNHGYYAGSNGEHDFVYFYRHFLRGQVAEFEAMRPDQDWPSIGATSGSLYLGVFPVLRHGFNVR
>NC_021658.1|WP_020740060.1|11518631_11520686_+|M3-family-metallopeptidase
MTEATDNPLLSLGFEIPFDRIRSEHVEPAVRALLADARARLEALIAAPGPRTYESTLAALEAVTERLDRAMNVVSHLESTSTTPELRAAYNAVQPEVSEFLSGIALNEGVYGALKAFAATPEAAALTGPRRRFFKKTLDDFRRSGAELDPPGKKRLSEIDVELATLTLRFSQNVLDATNAFEFVVEDPARLAGLPPSAIEAARQSAQDKGVKGYRFTLQAPSYIPVLTHLDDASIRERFYRAYNTRATEGDHDNRPLIRRILELRREKAKLLGYATFADLVLEDRMAKTGAEARRFVATLRERTEPVFAREKDELAAFRREIEGPGAPPIAPWDVSYYAEKLRRARYDFDDEALRPYFPLDRVVSGLFEIAHRLYGVRIAPWQDAPTWHPTVRAYRLLEADGAQSAAFYLDFAPREQKRDGAWMHGLVTGAPSDGGRAAGEDARHLEVLAGSFTPPVGGRPALLNHREVETLFHEFGHMMHHASSRVPIRSLAGTNVAWDFVELPSQIMENWCWEREALDLFARHHETGAPVPDDLLQRMRAARTFRAGAVTMRQLGFAEIDLALHVDWTPEHGDVVDFAREVLERYSPVPLPEGYAMIAGFSHLFSSPVGYAAGYYSYKWAEVLDADAFSRFQEEGLFSRKVGDAFRSQVLALGDTQDPMDLYKSFRGREPTLDALLQRSGLA
>NC_021658.1|WP_020740059.1|11517295_11518480_+|acyl-CoA-dehydrogenase-family-protein
MDFGWTPAQRAVHDRMRALGAEADAAAPDDRMRVLARGGALGLPIARDLGGEGLDLVTTALAYEGLGATLRDGGVLLAAGAHLFGVALLLARVGTPAQQRAWLPRMATGERMATVAATEAGAGSDVASVEATADRTAAGYRLTGEKRYVTWADRADVYFAIARDGGDGRAGGAPARGLTALLVPRDAAGGADAAGAPAAAEGRGAARVRPGAPLATAGLRGARLAPVSFAGCEVGPDALLGRAGAGLAVFQIAMTYERALILAFRLGALERALGEAVRFARERALGGQSIARHQAVAHRLARMKLRLETSRLLVYRAAWELDQGHRGQAEAALAKWHTADSALQSALDDLQLRGGAGYLEESGLPSAVDDALGGSIHSGTSDVLATIVARWLGV
>NC_021658.1|WP_020740058.1|11516650_11517208_+|Fis-family-transcriptional-regulator
MTTLGPRLPRLSRLSLVLALTAACSGSSDDEATAGQAAGEPPEMAGITAAHNRARATVDPPADDPIPVLTWSPEIAAVAQAYADGCVFGHSKSSYGENLYATSGAAASPEDVVAAWVDEAANYDLSSNSCSSTCGHYTQVVWADSLRLGCGVADCSGDSPFGGGSWQLWVCNYDPPGNFVGERPY
>NC_021658.1|WP_187345746.1|11540354_11542775_-|hypothetical-protein
MVPIAALPADVRAAGAGQGADPWALFDGRADTGLRSETGEVMRVRVSFSQPTALEALALYGRVDGALTVYAEHGAQLQAVSGLVDVPLHDTGERWTRFPMAITAQRLVLEWLPSSERGPQELVFWTAGAPTRSLAEVELADRVLAGKLAGATQFPAMSERAAVTRTGGEQSLTFHMDTDPRALARAFLVYELEGRGHWSSVSRQLNGAAPRGGFRAEALATGGLQVEEIAPAWLKRGDNVVRFRPQADIEHGFTVSALRVVGIPHAGVHEARAAARPDGGERARRDESLRIDFGARVAPHALLFQLTAAGAGEVEITPRAGANGLRFDLKDRSPGWHRLDLPLQSIWPEMASVHIRPAKGSRAEVSDVAVAASLIPSRSPRIALSTPLHGECTDGRAYVRGFLDLPGEGTPRARLFADAAPVELGDDGSFELTLPEPEGARHRSWRAHLEARLEDGTRLGRAVELGPCAESAAASAAPGALVADEGAPYGAVVSPEQGGVLSFAGATIEVPPGALEEATRITIRPLMPVQVQPMGRAMRNVTPEERAFRFGPLGLRFKKPVKLTLPIDGERLPDGAGARDVFGFYFDETAKQWTKLGRADEGRTRELTSLTDHFTDFVNATIAMPDQPGAQSFDPNAMKGIELASPSAGVSFIEPPEANSRGTAQLTYPIEVPPGRHGLEPELAVTYESELSNGWLGVGWDLRLSAIEIDTRFGVPRTTGDELYTLDGQMLRAIPDQPGRYGRPMAGSGCSSIRSGSTTRSTRAAPPPPTTTCSSSWTTARSGETSSARRAPASRCERREGWSAST
>NC_021658.1|WP_020740067.1|11543302_11544109_+|hypothetical-protein
MRNLTIGDLKLALRDLLDERAEELRLSATGRLYEPRLRARQKEIEALPEAAGTQAPLARELSEADVRHDGIGAAIFFLCKAVEAHPSLAPEVKAAAAGAQQAFVPRLDVLRAPYADEASAALDNRPELTRLKAELKAVATPGGGSLHEWVKAFVSAGDEIDKLLRRRATLLATGENAAATGPLRGAVVGLLGRFREALRDEIQEEGSRLPADHEARLFAYVDKLNADRERGARGRAAPTVGGPAAPGEPEAPGEPAPAEPVAVNDSDL
>NC_021658.1|WP_148314320.1|11544811_11548186_-|VCBS-repeat-containing-protein
MGQPKQGGISRGVRVLGAVLVSFVLWACNGVLGIGEFTSAVCQEGARQCKDDRPQICSAGQWRNASESPCVGQTCVAGECTGSCAPGGKRCQGLTPQACDENGRWKSTREPCDSAPGYHCSGGECVQTCTPGDLQCSGTSPQYCDANGSWQNNGDVCDPCVGCDPDTAACKNGEPVACGVGESCGNGTCICRNPGFTLSFLVGNSPASVAAVDLNGDGQPDLAVANSGSDTVSVLRNEDNGTFAPKIDYPTGRSPKTVAAAELNGDGQPDLAVANYGSNTVSVLRNEGNGTFAPKIDYSTGRSPKTVAAAELNGDGQPDLAVANSESNTLSVLVNEGNGTFAPKVDYPTGNSPYSVAAADLNGDGQPDLAVANFHSNTVSVLVNEGNGTFAPKIDYPTGNGPYSVAAADLNGDDRPDLVVANVYSNAVSVLRNEDSGTFAPKVDYPTGNGPYSVAAADLNGDDRPDLVVANVYSNAVSVLRNEDSGTFAPKVDYPTGNGPYSVAAADLNGDGPPDLAVANSDSNTVSVLLNEGSGTFAPKVDYPTGDLPYAVAAADLNRDDRPDLAVANSDSNTVSVLHNEGDGTFAPTRDYPMGNRTTSVAAADLNGDGQPDLAVANVYGNTVSVLRNEGNGGIFASTLDYPTGEYPTSVAAADLNGDGQPDLAVANVYGNTVSVLRNEGNGTFAPKVDYPAGDSPTSVAAADLNGDDRLDLAVANHGSNTVSVLRNEGNGTFAPKVDYPAGDSPTSVAAADLNGDDRLDLAVANHGSNTVSVLRNEGNGTFAPKVDYSTGGSPESVAAADLNGDGQPDLAVANDDSDTVSVRLNNGDGTFAPKVDYPAGDLPYSVAAADLSGDGQLDLAVANYGSGTVSVLRNEGNGTFAPKVDYPTGDYPTSVAAADLNGDGQPDLAVANHGSDTVSVRLNNGDGTLAPKLDFPTGDWSRFIAAADLNGDGHTDLAVANHGSDTVSVRLNNGDGTLAPKLDFPTGDGSRFIAAADLNGDGRPDLAVANHGSDTVSVRLNNGDGTLAPKLDFPTGDGSRFIAAADLNGDGRPDLAVANSGGDSVSVLLNNGNGTFAVKVDYQTGSNPESIAVADLNGDSKPDLAIPNVTSDAVSILPNNCIP
>NC_021658.1|WP_187345747.1|11548185_11549586_-|PEGA-domain-containing-protein
MLLDAGAKAAPPAPPGKAPHAATSSEEAEARAHFEEGVARFDKREYREALEAFRRSLWLKKNRNTMGYVASCLKQLGQYDDALEQYEEMRREYPKLPAKIEAMVSADMAELSGLVGTLAVAGDAPAGASLFVDDRLRGRLPLEMPLRVSAGRRAVRVEKEGVEPIRTTVDVRAGKENVAELVATSRDGWLVVSEKHNWVLHVELDGKHVGVTPWRGLVDVGEHKVRLHGFIWEEALLACDAPTTVAEHGAKVASSVTTASVRLYEETRVVLGAEEQDASLRVESTPTGATVRIDSKAVGKAPWEGRLPLGKHEIEVSAGGFFPAKQTVQLERRKQRELSVSLERQPDLEAEARAARNRKIGVGLAYGVGVAGLGVFAVTGGLALNRLNELNARCPNKQCPSTEAGNQRAAEALGTAATVGLVVAGLGAGAGTAVLLLTRPGDGERRVGPSVSAGVGLGGFEVRGRF
>NC_021658.1|WP_148314321.1|11549682_11550114_-|hypothetical-protein
MCLVACGRPTAGADGGVPGADGGAPAVSSAVSAALPRAAARTGMAVLGPDERRVPLLVVPGDALVEVNGQTAYRRDGAIDLVGKVGDQRWVRVWKGAKAAEKPVLIQENQPSPPFIDLNEAPPPRPAPKAPKRPARFGGFDDG
>NC_021658.1|WP_020740071.1|11550170_11553887_-|hypothetical-protein
MSGSTPPEGAPADEAPADEAPSSLAVPSIGRPSGADAERTGIFTAPNPFPGPQPYRAADRERFHGREELSYRLEASVLANRCVTVYGPSGAGKSSLMQASVIPSLVDTQRIRVVRIDAWPENKEPTEWLADAVYTALSFGERPADLPAEEALLSAAQRAGRKSPRIVLLYLDQIEQLLYPSRSTTEVEAFFAALNRLVDTPLRGLRAVLLLREDYLGRFRDRLREHRRLLSHGFRVGPLTVAELSEAVCKAAAGGQPPQTWELEPMRTLLLQVRMPGQAESDEAEAQAAYAQIVCRALFQQRAQGGDAAKQEAVEAEPILRRYLEATLDDLGALSAAARRLLEDHLVTADGSRTLRTEKELLRLFPAEELGPILKALEGAAILHAEEHQGSRYFEIGHDWLARRVSEARQQRELEEAQRRREEEQVRELARERGEAERRLRKARAQRRFFATVAVVAVVVAAGAVVLVLYAYGQRERAQAAMSEAQAAEANAKNKEIEASDARLLAGFRELKNGGQMAWGIKLLPEVKRPETARGWVALASDALGQNSLFVTLRGHDQPLRAAVWSHDGQWVLSASDDTTARLWNAGGTGDPVVFSGHQGAISAVAFSPDDKRVLTASEDGTARLWGAGGNLIAVLLDAGSGPVRRAAWSPDGGRVVTASADHVARVHSVDGGGVVELKGHTGPLNAAVFFDDGTRVLTASDDGTARVWAADGAGKPVILRGSEAGVLFAVPSPDGTRVLTGCSDGTARIFDASGKGKPVVLEGHQGNVLFAAWSRDGARVATASADKTARIWGADGTGEPVVLAGHGRAVTFVAFRPDGRYVATASLDHTVRLWPSEGGKDLVLAGHDAPVLSAAWSPDGTRVLTAAAPQVGVPSRDSTVRIWRPTMLESLPRERSAFYHSAFVGPGAELVASAYDDRTVRVWRADGTGESVVLAQQDAWIANASLSPDGARVAVAGFDGVTRIVRVDAKGDPVSILGHTAAVRAAAWSPGGTLLVTVSDDRTARVVSVNGAGSARVLSGHTDGLTSAAWSPDAQRIVTTSMDHTARVWLASAAQELVAFKGHGGAVYSAAWSPDGAWIATGSEDGTVQVWDARSGAVAASLDRGVAVLQAIWSPGGDRIAVSLRQGGVLLWSREAWERPGMSEPVQLDTQAAILAMAFLDGGKRLFTVAADNTTRTFTIDADELRRGLLSSNVDCLPASLRVLHLGEAPDRASERYAACEREHSRTPFFGSGQEGQ
>NC_021658.1|WP_020740072.1|11553883_11555875_-|CHAT-domain-containing-protein
MWIEIEVDAVAQGVRVSARGSRGERPPAHTLSPGLGMDALQNLASKVGRAVRGGRALDPAVVEEAQALYGELLKDDLRDVLVRLREASKDSPLLVRLFLRDRALLGIPWEALCRPGTTEGFLGTDPKVLLARGVTSPDPWEPRDVLGAVRVLAIAPGRDERSLVVLKEALASSIEAGEVEWLDPIAGPHIGAQALFDRLRRGKTPHVLHWLGHGGVDLSGKPVLRVADDEDGEEVWITAEALGRELSASFSEELRLVILEACEGAKAGAFGSAAEILASAGADAVVAHLWPVKADVARLCSSEIYRSLTGSERGLGDIGASVAAARRTLLAQSAEAFSPVLFLRGTGSAIFDFSDRRVSKQRARRGSRGLSPALQSLLETPFTMVLGDLEEDRAALRTELLSFMKESGDTAPEALSLSALTQRCALKFGQESLHVLFQQALTTSLEVPAPPLARALARFVGPGVHMTLLWRPHMERAIAETHPERSVFAIQPSLLGASGKPLVVKRAAGAAAWKMEPVLPKRFDLDGDIVILRLYGGYSAGPRPIFSHPVLTEDDHIHGLLGAIGFDPPVWMEELLARPRVQPGLFVGLSALDFRHRMLLRWLYDQRQPPSDSLAILTPDTDPSEPEIWEGGCGLPGGGRIASVIEDPELVPQLEAFAPDEAS
>NC_021658.1|WP_187345748.1|11556129_11557659_+|PEGA-domain-containing-protein
MRRFRARAMAGWILALGLLGAETRAEPADDTAKFDIYTGEPLARAHSDDEAPARAHSDDKAPARAHFERGVARFDRQEYREALEEFRKSLEHKRTRNAMGYVASCLKQLGQYDDALEQYEAMRSEYPELPPRTEATVAADMAELAGLVGTLVLRGDVPAGASLFIDDRFRGRLPLDKPLRLSVGSRAVRVEKEGFAPIATTVEVKAGRENVAELVATSRKGRLRVSERHNWPLEIEIDGKATGAVTPWEGLLDPGEHTVRLRGFLDEEALLSCDVPGAMPGGKWAAARQGAKMESGVKTVNVRLYDVAEVVLGAEDQDASLKIESAPTGARLWIDGKEVGQTPWEGRLPLGEHAIGVRADGYLYARQEVTLERRKQREVTVALDRVPGFWTAEFWTARTVGATAGYGTGVLGLGVFAVSGVLALNTSADLKQACPGGLCPRDRAAQKERAHALGVTALAGLIVGGAGAVAGTVVLVAARPEREEKRVTSAGTAWEVGVGPFGLSLGGSF
>NC_021658.1|WP_148314322.1|11558069_11560490_+|VCBS-repeat-containing-protein
MDQTCKDGECVGDCAPGKRCIGVTPEACSDEGEWEAGEPCDSDAGFHCSGGECVQTCTPGDYQCSGSIPQVCDANGIWQINGPVCDPCVGCDPTTAACRTSDPVVCLVGESCGNGECICAHPGFTGMLFFPAGNGPASVVAADLNGDGQSDLAVANIDSNIVSVLLNNGDGTFAPKVDSPTGGRLTSVAAADLNGDGKPDLAVANGDSNTVGVLLNKGDGTFEPWVDYPTGGAPTAVAAANLSDDSLPDLAVATSTGVSVLLNEGNGTFAPKVDYFISRGISSVAAADLNIDGKPDLAIASKGNPVVSVMLNDGDGTFAPEVDYHTSDRPPNSVAAADLNDDGRPELVVTDEFSGTVSVLLNNGDSTFAPKVDYPVGDAPNSVAAADLNGDGRPDLAVANLDSDIVSVLLNKGDGTFAPKVDYPTSDGPRSITAADLNDDGKPDLAIANLYSNTVGVLLNNGSDTFTAAHDYATSGDPGWVVAADLSGDGKPDLAIANVGSDTVSVLLNNGDGTFAPKVAYPTGGDGISVAAEDLNGDRTPDLAVANVGSDTVSVLLNNGDGTFAPKVDYPTDDGPRSIAAADLNGDGMPDLAIANQSSDTVSVLLNKGDGTCAPKVDYPTGGGAISVAAADLNGDGMLDLAIANPSSATVSVLLNDGDGTFAPKVDYPTGENPVSVAAADLNGDRTPDLVVTNYVSATASVLINNGNGTFALKVDYPTGNNPTSVAAADLNDDRKTDLAVTNYGDTASVLLNNGDGTFAPKVDYPTGRLPRSVAAADLNGDGRPDLAVANVGSNTVSILLNICVP
>NC_021658.1|WP_020740074.1|11560963_11562670_+|adenylate/guanylate-cyclase-domain-containing-protein
MQPFMFRLGTVRAKLTVLVALSSLATLAALPVLSWVMHRQLLAQISERVPQAIRNFRLELRQQQRSISTSARQASRTRELVDGLRLRDDAAVGTALEAVIAAHPNVAIAAFDELGDLVAARGLDAPPASTDEVPGLAEGLSNLDEMEDLRDVLVHGCEGQQGAPPAYMIAQRARSDAGSLLACIPIDHTYFDEAATKLGVEIALVDPSGKRITGTARFPTELLQGASIGDETHPTIVEDASSLWALSRFAPRSLRGKAGDFSIVMALDVSDVRKIVRQNLMLAAGVLTLAALVSLILGARLATTMSRALSRVNVALKQLEQQQYVHVEGVKTGDELEDLAAGFNSMVDGLKERDKLRSTFGKYMTESVLEHLLAGKVQLGGETLTVSILFCDIRSFTTISEKMNAHELVGLLNEYFTEMVAIILDEGGVVDKYIGDAIMAVFGAPVPRPDDAVRAVRAAIRMRAALERFNERLAERGIPALKTGVGIHTGEVVAGNIGSEARMEYTVIGDAVNLASRLESATKELGVSVLLSEDTHRLVSDRFNTRPVSEITVKGRVQPVMTYAVANV

Crispr_ID: NC_021658_55

• CRISPR_ID: NC_021658_55
• CRISPR_location: 11695354-11695462
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_55

Consensus_repeat	Method
GGGCTCCGTCGGGACCGTGGGCTCCGT	CRISPRCasFinder

spacers of NC_021658_55

>55.1|11695381|55|NC_021658|CRISPRCasFinder
CGGGACCGTGGGCTCCGTCGGGACCGTGGGCTCCGTCGGGGTCGGGACCGTGGGC

CRISPR arrays and Neighbor proteins around NC_021658_55

CRISPR arrays

The CRISPR arrays of NC_021658_55

>merge|NC_021658|55|11695354-11695462|CRISPRCasFinder
GCGCTGCGCTTCCGCCGTGGGCTCCGTCGGGACCGTGGGCTCCGTCGGGACCGTGGGCTCCGTCGGGGTCGGGACCGTGGGCGGGCTCCGTCGGGACCGTGGGCCCCGT

>NC_021658|55|48|11695354-11695462|CRISPRCasFinder
GCGCTGCGCTTCCGCCGTGGGCTCCGT	CGGGACCGTGGGCTCCGTCGGGACCGTGGGCTCCGTCGGGGTCGGGACCGTGGGC
GGGCTCCGTCGGGACCGTGGGCCCCGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_063752070.1|11698791_11699670_-|LamG-domain-containing-protein	unknown	unknown	gnl|CDD|379155
NC_021658.1|WP_020740183.1|11711048_11711921_-|endonuclease-VIII	unknown	unknown	gnl|CDD|223344
NC_021658.1|WP_187345753.1|11693014_11695321_-|hypothetical-protein	unknown	unknown	gnl|CDD|226415
NC_021658.1|WP_020740169.1|11689984_11690527_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NC_021658.1|WP_020740182.1|11707404_11710524_-|ATP-binding-protein	unknown	unknown	gnl|CDD|214640
NC_021658.1|WP_148315008.1|11686428_11687679_-|hypothetical-protein	unknown	unknown	gnl|CDD|240291
NC_021658.1|WP_148314338.1|11684897_11685119_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949765.1|11700241_11702200_+|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl|CDD|275079
NC_021658.1|WP_020740179.1|11705873_11706683_-|cyanophycinase	unknown	unknown	gnl|CDD|131124
NC_021658.1|WP_020740166.1|11685136_11685937_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314341.1|11691902_11692745_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187345752.1|11688905_11689913_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NC_021658.1|WP_044986717.1|11711999_11714762_-|hypothetical-protein	unknown	unknown	gnl|CDD|366146
NC_021658.1|WP_044986715.1|11698139_11698547_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020740178.1|11703164_11705849_-|cyanophycin-synthetase	unknown	unknown	gnl|CDD|237586
NC_021658.1|WP_020740171.1|11690926_11691829_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176102
NC_021658.1|WP_187345754.1|11706749_11706923_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020740170.1|11690628_11690946_+|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|224278
NC_021658.1|WP_020740177.1|11702282_11703140_-|cyanophycinase	unknown	unknown	gnl|CDD|131124
NC_021658.1|WP_148314340.1|11688159_11688825_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_063752070.1|11698791_11699670_-|LamG-domain-containing-protein	gnl|CDD|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	8.01134e-27
NC_021658.1|WP_020740183.1|11711048_11711921_-|endonuclease-VIII	gnl|CDD|223344	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair].	6.43645e-44
NC_021658.1|WP_187345753.1|11693014_11695321_-|hypothetical-protein	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	8.87365e-25
NC_021658.1|WP_020740169.1|11689984_11690527_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.22371e-09
NC_021658.1|WP_020740182.1|11707404_11710524_-|ATP-binding-protein	gnl|CDD|214640	smart00382, AAA, ATPases associated with a variety of cellular activities. AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.	0.00251952
NC_021658.1|WP_148315008.1|11686428_11687679_-|hypothetical-protein	gnl|CDD|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.000424145
NC_021658.1|WP_044986717.1|11711999_11714762_-|hypothetical-protein	gnl|CDD|366146	pfam00520, Ion_trans, Ion transport protein. This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.	0.000242059
NC_021658.1|WP_049949765.1|11700241_11702200_+|right-handed-parallel-beta-helix-repeat-containing-protein	gnl|CDD|275079	TIGR04247, nitrous_oxide_maturation_protein_NosD, nitrous oxide reductase family maturation protein NosD. Members of this family include NosD, a repetitive periplasmic protein required for the maturation of the copper-containing enzyme nitrous-oxide reductase. NosD appears to be part of a complex with NosF (an ABC transporter family ATP-binding protein) and NosY (a six-helix transmembrane protein in the ABC-2 permease family). However, NosDFY-like complexes appear to occur also in species whose copper requiring enzymes are something other than nitrous-oxide reductase.	9.06918e-09
NC_021658.1|WP_020740179.1|11705873_11706683_-|cyanophycinase	gnl|CDD|131124	TIGR02069, cyanophycinase, cyanophycinase. This model describes both cytosolic and extracellular cyanophycinases. The former are part of a system in many Cyanobacteria and a few other species of generating and later utilizing a storage polymer for nitrogen, carbon, and energy, called cyanophycin. The latter are found in species such as Pseudomonas anguilliseptica that can use external cyanophycin. The polymer has a backbone of L-aspartic acid, with most Asp side chain carboxyl groups attached to L-arginine. [Energy metabolism, Other].	3.56213e-92
NC_021658.1|WP_020740171.1|11690926_11691829_-|LysR-family-transcriptional-regulator	gnl|CDD|176102	cd05466, PBP2_LTTR_substrate, The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily. This model and hierarchy represent the the substrate-binding domain of the LysR-type transcriptional regulators that form the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, oxidative stress responses, nodule formation of nitrogen-fixing bacteria, synthesis of virulence factors, toxin production, attachment and secretion, to name a few. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.91354e-40
NC_021658.1|WP_187345752.1|11688905_11689913_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	6.70345e-19
NC_021658.1|WP_020740178.1|11703164_11705849_-|cyanophycin-synthetase	gnl|CDD|237586	PRK14016, PRK14016, cyanophycin synthetase; Provisional.	0
NC_021658.1|WP_020740170.1|11690628_11690946_+|antibiotic-biosynthesis-monooxygenase	gnl|CDD|224278	COG1359, COG1359, Uncharacterized conserved protein [Function unknown].	3.84107e-06
NC_021658.1|WP_020740177.1|11702282_11703140_-|cyanophycinase	gnl|CDD|131124	TIGR02069, cyanophycinase, cyanophycinase. This model describes both cytosolic and extracellular cyanophycinases. The former are part of a system in many Cyanobacteria and a few other species of generating and later utilizing a storage polymer for nitrogen, carbon, and energy, called cyanophycin. The latter are found in species such as Pseudomonas anguilliseptica that can use external cyanophycin. The polymer has a backbone of L-aspartic acid, with most Asp side chain carboxyl groups attached to L-arginine. [Energy metabolism, Other].	4.74624e-91

Protein sequences

>NC_021658.1|WP_187345753.1|11693014_11695321_-|hypothetical-protein
MSSGSAFGLLSRALRGVMGIVDGEPLEERRRKVRARVERHPELDVGRVSAFLGELVGAPFPDDDIQVGAARRNRLLMGDQLRLSWEEFIRAECAKQPVVLILEDLQWGDLPTLTMVEAALRSLKDLPFLVLGLGRPEVHEIFPALAKGRFGNQLMLPPLTRRASERLVRAALGDEVGAELVATLVDRADGNPFYLEEQVRAVAAGHGADLPETVLAMVQARIEALDADARRVLRAASVFGQAFWPSGVSALLGGAGVTRWLSELEKREVIHRRGPGRLRGEVEYRFRHALVREAAYGMLTEADRRLGHALAGDWLEGAGEPDAMALAEHFERGAVPARAAAAYLRAAQHALEGNDLGAAIARAERGLACAPEPAVVGALRLVQAEAHVWRGDLALAEERGTAAVEHLTPGSAPWFTAVAQVVAAASKLGGFDRVERWMGAAIGAPALSGAESARSTCLCAGASTLAFAGRPAVVDALIAEVERALSDGAATGAGTGAEVVAGLHQARAFRAMSGGDPGACATGLEAALAAFEQVGDRRNACITRANLGYCYGELGDFGGAEAALRSVMEAAERMGLHEVAAAAQASLGQVLAYVGRLAEARAVEEAALASSQRLGDPRAEVVSRSYLAKIALLAGDFTGAEREARHAEALESASPFRVAATAIRARALIGLGRAAEALAAAGEALAALESLGGLEEGESMIRLVHAEAFSAVGDAARAAVAISSARDRLLGRAESVRDPEWRRRFLSHVPDNARTLELAAQWVGTGRN
>NC_021658.1|WP_148314341.1|11691902_11692745_-|hypothetical-protein
MNIKAVLGCAGILLVANGCVAPELAFEEDGEAEELGSSADAIESGNALSYNALSYNALSYNALSYNALSYNALRPEAASALRDPGVGGELFRTLVKYTVSCAFKESQSFRFSWTDAAGATHNEVYPGHLGLADRWGRRPLDEDGKQMVSACLAAHTNRYGVSVLISMRSPQNPLRREVESDELSAYPHLEGAFWGNLFSDTPYLRACYDEANVEVARAARRDCAAGHPGADGDLEGCGIIEIVGSCQDTCGKVHRPGQYYKHCDDPESGKTRYVITTGLR
>NC_021658.1|WP_020740171.1|11690926_11691829_-|LysR-family-transcriptional-regulator
MEIHQVRYFLAVTETRSFTRAAERCSVSQPALTAAIKKLEEELGGPLLLRERGGAKLTALGQGVLPRFLRLRDDMQAVQVIAENHRRLKQVPLRVGILCTVGPARLAGSLSAFRAEAPGVELEIAVTTQGELLRRLEEAEVDVIVSNLGDAVPDWCVVAPLYEERYVVVLPPGHRLAAREGLRLEDLDGEPYLDRLACEMREQVAGVCAARRVDLYAAYRTDREDWVQSLVHAGLGFAFMPEHSLLLTEASQRPLVDPALRRTIALVRSGDRTPAPVLQLFWDTLLARAARPRPVKPSRR
>NC_021658.1|WP_020740170.1|11690628_11690946_+|antibiotic-biosynthesis-monooxygenase
MTADPTKAVTLSLLARIEAKPGKEAEVEALLRSAVGLAAEEPRTVHWFALRIGPSTFGIFDTFADEAGRKEHLAGRIAAALMAKAEELLAAAPVIEHVDIIAAKV
>NC_021658.1|WP_020740169.1|11689984_11690527_+|sigma-70-family-RNA-polymerase-sigma-factor
MLDIDSIARHTATIDDVLRRWRIPSRDRADIVQEVLLGAWRSMRAGRFQPRPGVPDAVALKRWIVGISWRHASHYATRAHRRYEVLVPSAGRLCQDHAPAPLEQVEARRALDDLRRVDPRFRAVLALTAQGYTIAEIAAEIGHNPNTVWNRLRLGRLWFRRVRRRWRRLARARREHHPRR
>NC_021658.1|WP_187345752.1|11688905_11689913_+|sigma-70-family-RNA-polymerase-sigma-factor
MPAQDVDDVVQQAWLRILENRARIGLARDAAAYADQIVRNEARTSRRRARRREEVTAPLQGAEPSDERPGPEASVIARQRAAVLWQFIDKLDDARRTVFVEHELQGRTLAEIALTHALSENTVKSRLAAAWDSVERERARWQAEQRWRGQATVPCVVPFFSGTWLHEALRGLGRFKLHGAAAAALVLGAGAAWPGPAAGSTEAPLLAASGRAQPAVEIPAGPADARVGPGGPESAIGREAVTASAVSSYQGSSTTARAVSAAVERSSRGGTGAEHARTDPRIERARAMLDLGTTEGQLSACRLLHEHRERRGRGEHAAERDALLRRARCERHGSL
>NC_021658.1|WP_148314340.1|11688159_11688825_+|hypothetical-protein
MSFKAHVGDAHGGNADRVSTQAAPAIAAVPSFAPLTSIPIIVQSMLPAEATREAYATRLACPADPAIAASAGHHRTGIDRDLGAPQHEDPDARAPVAPSLARLSTAAAALSADRDPSGAGCARASPTPLPSATRQQIPPTTERKRIMRPTIPTEPPAQQPRLHAERCALHDKSDATLVMYSTETPSSRHPRVGAPSRTVSSSRRSMGSPLFGPESSGRAWT
>NC_021658.1|WP_148315008.1|11686428_11687679_-|hypothetical-protein
MFLCSRHSGAITLPSGVDLVGSFDCTNDWKRRNPSDDPIISSFPVGVALTIEPARPDDTGAADGVSTLVNVRIGTTKDVGLLVRSGSAVEIVRSERFGSPRYRAADDARTLPDPPEGAPGNGGVQGCSVAPAAGGAPAMSSCHDGAVTIGGKGGDGGATASGDGGDAGDGVPAPGPDASPDDRRWGAGGTGDHGDGRCQDGQPGKDGAPGVDGAPGQGIGRLSENGWIGSRAWEGSRGRPGQGGGGGGGLRGSAALCGVASRSGPSGGSGGGGGCGGNGGKGGSNGIPSIAILALHAKVTVRDSLIGTGPAMPGADGGAPQDGSRGGRGGIGAYSPDAIARACDGGDGGLGGPGGYGGGGRGGDSIGIAHLDDTELVLENVTFELGEPGVGGIGNPADPATWGEDGIAVETLRFPE
>NC_021658.1|WP_020740166.1|11685136_11685937_+|hypothetical-protein
MKPAQPREPRTIRRTSDRDDKEAAAINNAFYVLLEMTSARRLSTLVRRPTRSEVLAALDDFIAYFVLDQPRERARELREAVLTWREDEEIPQAVYDGARRFILSLGVREPACGWANDDGDQVRAIDRDTDDAEPPPAAEAAPWSYSDASRRAAQLAQAVAGVMNIAGALASPSSWARATSRPSREHLVEHIDQLLSAFGTDLEEQKFAAPARTLRALLSAWEPGADVPVDISDAARELLAAMGIQEPPEGWDALEGPSEGPSNDSG
>NC_021658.1|WP_148314338.1|11684897_11685119_+|hypothetical-protein
MNHRCIIDDCGEAKCPTCPDFVNELLQNTVIRSWCSYVCIQIGTSPLEVVAVGAGAMSALGGKFFGPICKPYP
>NC_021658.1|WP_044986715.1|11698139_11698547_+|hypothetical-protein
MSMSMKLMGAVLMSVGIGFAGAAWAAGGAADVPASVAEGKDFGCGAKGQKACPMQGWMKTVMQSATTSGDGAKIASALDYVASKPPPGMPKWVAISKEGAEKAKKGDIDGAKASCKACHDLYKAEYKAKLRDAAF
>NC_021658.1|WP_063752070.1|11698791_11699670_-|LamG-domain-containing-protein
MAYSSRFSPRCLAGMAALLLSVPGCALDARGTRQPERAEPRPEQPVEEPAGDIGEAPAEGPPVDAPAEGPVEVPAEEPAEEPVEEPAEEPAALCDAADPSLIACFAFEGDPGDGSQHRFKPEQAENLSYEPGKGGQALRVTRKSSLRFRHDAAWAAPAMTIDVWINPASLPKSGRYAVIDSGGKPSIFLTAGGEIRCTMGVERNVPYAVVPGEWTHIACLSDGQTQSLYVNGVEIDRSSSGAVLASGEQPIFIGSEEPSGKDEFDGLLDSLRVFGRTLAPEEICAAAGGNAC
>NC_021658.1|WP_049949765.1|11700241_11702200_+|right-handed-parallel-beta-helix-repeat-containing-protein
MPPAEAPDGGGGTAAPGCAPGELATASGCEPAGIPPEACGAGFTPGDRACAPVLPPAPCAAGTMAVPGETACREVAPCGEGAWGDLPVDEQTQFVDAAYAGADADGSAAKPWRTVGDGVLAAAPGGVVAVAAGTYAEDVIVDKPVRLWGRCPAMVEIAGAGPDTSAAITVDPGADAAEIRGLAVRSAGVGIVVSGSSGVVVDEVWVHGTGAQGVKVYNEHGPAQLTVRGALIEEAHSVGAHCAGAELVLESSVVRGTLETAEFRGSGIGASRGEGDAPASVTVRGSIIEQSRGTGVYIIASEAVVEDSVIRDSLGIDADAAGMGVVAFRNSRGQPGEVAIRRSVIEGNEEAGMFVQGSSATVEDTVVRDTRPYPGKLRTGWGIYVVADIAAGLRSEATLERVVVERSRDVGVALFGADGSLDGVIVRDTLPRDMDGNHGIGLAVASGNELHGRVTARGAVIEGSRTAGVFIEGAEATLEGVAIRRTLPRASDERFGRGIAVQGLDAQGAPSRLELRSSLVEDSVETGLSIIGSTATLEATTVRGTRSSSDGLKGNGVTVSKDADDAEVTLTDVRIEENDGAAVASFGAAVSLERTTLECNFIDLNVEAELGTAGKITDSGQNQCGCQGVSIPCQVKSEGLTPPEPLPPALEP
>NC_021658.1|WP_020740177.1|11702282_11703140_-|cyanophycinase
MVGSKGNAEGPDREPPAGGPGGALVLIGGHEDKEGEREILRDVVARAGGRPIVVATVASDVAGELWVEYERVFRALGAAEVAHLDIAERGDAGEARWLSMLEGAGCVFFTGGDQLKITSKLGGSRLADAICAVYRRGGTIAGTSAGASVMSETMLVGGAGEESAKVRGAVRMAPGLGLVRDLLVDQHFAQRGRLGRLLGAVAHNPRLLGIGIDEDTAAAIEPDRRLRALGTGAVYVVDGRNLSHTNIGEEEGDRVLSLFDVRLHVLSAGDAFDLERGRPASGQPR
>NC_021658.1|WP_020740178.1|11703164_11705849_-|cyanophycin-synthetase
MRIITLRTLHGPNVFASWPVLRMTLDLEDLAETSSAEVPGFVDRLLALLPGLGEHHCSRGKPGGFVERLREGTYWGHIIEHVALELSGPAGIGVTYGKTVYAGAPGLYDVVVEFENEAAMRLLLEAAFELVTAVLEGGPFDVDAKVREAARVAEETALGPSTRAVVKAAEKRGIPWSRLNDESLLVFGYGKHRRFVQATTCSTTSFVAVEIAGDKQLTKELLARAGVPAPRGIAVRTAGEAARALGELRAPVVVKPLDGNQGKGVSLNLWTEAQVREAFEIARVHRPRVLIEEMVSGRNYRVLVVNGRVVAASERLPAHVVGDGQRTVAELIALENENPLRADGHNGVLTKIVVDDVVRACLAKRGRSLDEVPARGERFFLRESVNLSTGGIARDVTDEIHPDTARLCERAARAIDLDICGIDLVAEDIAKPLGRGAIIELNAAPGIRMHEHPSEGKPRDVGGAIVEMLYPPGAPSRIPILSITGTNGKTTTTRMVGHILGATGATVGMTTTEGIYVGGRCIEAGDTTGAGSARAILFDPTVDVAVLETARGGIVRRGLGYDWSDVAIMTNLSPDHLGQDGIESVDDLLWIKMVVAERVREGGTLVLNAEDPLLAAVPQHRRMTKLSRAIVFFALDPSNPVLRAHVAQGGTGYTLKNGSIVELKGTRERHIVGAADIPATFAGAALFQVQNAMAAIAACRAQGVPVDAIQSALRTFDACGKNRGRMNLYQLDDNYVLVDYGHNPGAFQATCALAAQWEGRRLTAIVSLPGDRSNALLEACACEIAKGGFHRILAKDDGDRRGRAPGELPALVQRVLAEVRPEQACVVIPDEHEAIEHALATAEPGEVIVLFTEEAPAMEEMLTRMGAVAVNAVPELRSGTRLRARRREDALLAV
>NC_021658.1|WP_020740179.1|11705873_11706683_-|cyanophycinase
MVPATSFPRLLAIGGAEDKEGERAILREFVRLAGGQDACIVIIPSASETPEVVGELYQHIFQQLGASEVTVLTIAARDDARNEAAMRQVERATGTFFTGGDQLRIMNRLGGTGVDTMLHRRCAEGMVVGGTSAGAAVMSSTMIVEGETRSPRAGAVRTGPGLELLPGVIIDQHFAQRGRIGRLLSVIALFPHYLGVGIDEDTAIAVEGHRATVIGSGAVTIVDAGCASFNDAVDTGPGGCITLSGVTLHSLPHGRSFDLLERRPIIAAD
>NC_021658.1|WP_187345754.1|11706749_11706923_-|hypothetical-protein
MLKHPRDEELAALDLLPEDGQAQPAGARRVNADLSHSGEGQSTTLWQFAMVQIEPPH
>NC_021658.1|WP_020740182.1|11707404_11710524_-|ATP-binding-protein
MVATVLFISANPPGTKPLDIEREERTIKEELEIRAKYRDYIRVRNAPAARAMDFREHLIRELPTVVHFSGHGQRCCAMLRETDVGREARDLQPAATADASAGEPAPGRILVRGEGEGTEWVPTGPLVELFASLRGRIPTRCVVLNACFTEAQAKDIAEHIDFVVGTTGSIPDRAAIVFSKAFYWALGEGMSFAEAFELGKGAIGLESAGDPAILRCWCTKDNAEELHLIDLFHPYVELLSTRLADFKAFARSAESDLHGPIRLGEGPEDGLDLTGGDIVFLSGWSGRGKTTALLMLARRATRDDAQARIPIVLRAEAVDVTVPRAIFATLNQVTESFRSEADLIRWMNLRPTLLLIDDWHRAGDAARRTIAEFIATLRPAMMAVVIAGAPTIPPPATPGLQRIELGRYSVEERDAHIRDFFGSIWGTAHWVLEGLPDGLSELLREPVILNKYLRLVRRYAAGTRLPSNVPDLLDTLLEQLLQSRDANARLRLTELSALCTDLAQQGRRFGLAAVAESARRLGLAEGASASHAEDLEASGVLRRDGAGFEFEHEIWRRHFEAKALLEGGRWDSPPGIREWVAVTDRSALFELLPFACGLIRGADTQEALLDALLEKDLELYIRALPLRADIRARERVDIFAERSLRALHRGYVDLVERHFAAFKDSIEPWCFGDCEGQKAVLIGELHPPRLTYSFVLGSERADDVILAHDHRGGLALDAEATVDALLPFPVDPSSDASPMLGVTYNEGDRCVRGLDLARSLMRPGSTRLIAAELLINNIKEILKQKAIVTPWSMREYFGSTLIHADRQGGYDTWLRLTVAEAMRLASLSLEVAPLPQDENEPAFLNESELDAQNLRKIIAFGNCLVSYGLGESTVGDIVLPGPELVDGEWRYTVERRVKRVEAFYQATAETYRLLCDGLSDEVKSQIHFSQWPCRAVVEIEVLDDNESAGWEMYWEACESWGTPPIVHAVEGRSRLLSNYEQLMVHERRSCKRWRRRFMGVRAKGTRGAWALWSEAVTEEVCDMLLDDLIVIQRWLTNAT
>NC_021658.1|WP_020740183.1|11711048_11711921_-|endonuclease-VIII
MPERPDLEYVVPILARELAGAAVAAARADSPVVLRVLLPERLDALLPGAEIRRVTRRAHAVVFELAGARALDLVIAPMLAGRFSITLPGETRVPTDLAFSLALKDGRELRVRDEVEMSKVYVLARGEYDKIPGLERVGLDVLEPRVFTQEAFRAAAHGRRDLVKDFLMDKAALDSLGNAYADEVLFEAQIHPKATVKGLSDEELDRLHAAIARVLGDATRTIARRAPALDEKLRDFLKVRGRPGQPCPRCGDKLRRASVHGHDAIYCPTCQPEEGKGAAADLRRAKRTPG
>NC_021658.1|WP_044986717.1|11711999_11714762_-|hypothetical-protein
MAPRQPLLLRLAGGLETRPVKAALSLLILVSVLPIQGLEDELRPYFLGIFGVELLLRAALLRQRGRERSRLDVVLFAFDVIAWLSFLPLERLLDAHAAHALPVLRLTRLFLLLRFTREIAIDLYAIMTRRELLEQFGLVTLAVWGLAFGASVLLSHLAISHDYDGRGPVPDATFFDRIWWSFRQLESADNLVANLHVHPVVAVLSLGLTMVGVFITSFIIGIGANVVDQVVRAARRRPVGYAGHALVIGPVHEAEMLVQEFVRLYERHRALRSIRLSELWVWLVRRGPPPTRHALPRMALLGTEDDPPAYLYAPRMRWVAYRTGDSAQPEALGLVGAVGAKRALILARPDAGPDADAVTAMALSSFRTQNRRGHVFVEVQESKNRDLLQAVGGPGTYPLDMQRFLGFFLCQHLITPGVEALYTDLMTADGSEFYTHIFLGEEAVRTVAALGEGPGGEISFSRMARAACQSNVILAGVFLGDGVPERRAGELVSTEGLVQWLNPLLDPPEGSPAWALGARAGRVPARRLRGLIGVSATYAPLRRYGRELLMGRGIAPAEAADGAGATGGAGAAANDAGATHGAGAAANDAGATDGAGATRAWAATLSPRQSRLDRVLIVGYSPALPSLLNALAQFVPGIEVTLVLGERGDERMPLADRLASLGVAPAPDGAPPGQAGARFALPRGGSATVYTQHGHDLASLAVRCAARGAPASAAVFLSEPEGLDRDARTAMRLIRFARALESGELAHGARLHVLAEFSSVAKGEHVRSLLDAGKCGFAGPDRLRLSLVSTERIKNYFMVHSAFVPGVTTLYDELLGEGGQDLVRIEAPPPGPGERVNGASAFEELRAALEPRGVIPMALELDDGAVLLNPEPGPALAAARIRAVYALARGRDLAAYGDRRPEEGEGREAARGEQAPRISA

Crispr_ID: NC_021658_56

• CRISPR_ID: NC_021658_56
• CRISPR_location: 12553389-12553489
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_56

Consensus_repeat	Method
CTACCGCGGCACGGCAGAGAGCTACCGCCGGCACGG	CRISPRCasFinder

spacers of NC_021658_56

>56.1|12553425|29|NC_021658|CRISPRCasFinder
CAGAGAGGCTACCGCGGCACGGCAGAGAG

CRISPR arrays and Neighbor proteins around NC_021658_56

CRISPR arrays

The CRISPR arrays of NC_021658_56

>merge|NC_021658|56|12553389-12553489|CRISPRCasFinder
CTACCGCGGCACGGCAGAGAGCTACCGCCGGCACGGCAGAGAGGCTACCGCGGCACGGCAGAGAGCTACCGCGGCACGGCAGAGAGCTACCGCGGCACGGA

>NC_021658|56|49|12553389-12553489|CRISPRCasFinder
CTACCGCGGCACGGCAGAGAGCTACCGCCGGCACGG	CAGAGAGGCTACCGCGGCACGGCAGAGAG
CTACCGCGGCACGGCAGAGAGCTACCGCGGCACGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020740781.1|12565397_12566669_-|cytochrome-c	unknown	unknown	unknown
NC_021658.1|WP_020740758.1|12532864_12533713_+|thioredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|239321
NC_021658.1|WP_020740782.1|12566665_12568033_-|DUF1501-domain-containing-protein	unknown	unknown	gnl|CDD|369346
NC_021658.1|WP_148314422.1|12546301_12546643_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187345773.1|12556892_12557060_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020740766.1|12544290_12544773_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020740770.1|12550927_12553228_-|helicase	unknown	unknown	gnl|CDD|350192
NC_021658.1|WP_020740768.1|12549142_12549520_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_187345774.1|12557074_12557773_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314425.1|12559163_12560573_-|DUF1552-domain-containing-protein	unknown	unknown	gnl|CDD|377875
NC_021658.1|WP_148315039.1|12557956_12558865_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381326
NC_021658.1|WP_044989478.1|12539733_12540360_+|glycoside-hydrolase-family-11-protein	unknown	unknown	gnl|CDD|366111
NC_021658.1|WP_020740780.1|12563576_12565268_-|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|277316
NC_021658.1|WP_080682581.1|12562559_12563471_-|hypothetical-protein	unknown	unknown	gnl|CDD|333766
NC_021658.1|WP_020740763.1|12540508_12541141_-|glutathione-S-transferase-family-protein	unknown	unknown	gnl|CDD|223698
NC_021658.1|WP_080682806.1|12533717_12534635_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187632
NC_021658.1|WP_044986884.1|12535851_12536964_-|hypothetical-protein	unknown	unknown	gnl|CDD|215598
NC_021658.1|WP_020740772.1|12556453_12556612_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314423.1|12549607_12550492_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314426.1|12560569_12562294_-|DUF1592-domain-containing-protein	unknown	unknown	gnl|CDD|377886

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020740758.1|12532864_12533713_+|thioredoxin-domain-containing-protein	gnl|CDD|239321	cd03023, DsbA_Com1_like, DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC motif, assumed to be imbedded in a DsbA-like structure. Its homology to DsbA suggests that the protein is a protein disulfide oxidoreductase. The role of such a protein in pathogenesis is unknown.	2.53962e-34
NC_021658.1|WP_148314426.1|12560569_12562294_-|DUF1592-domain-containing-protein	gnl|CDD|377886	pfam07631, PSD4, Protein of unknown function (DUF1592). A region of similarity shared by several Rhodopirellula baltica cytochrome-like proteins that are predicted to be secreted. These proteins also match pfam07627, pfam07626, and pfam07624.	2.1223e-54
NC_021658.1|WP_148314425.1|12559163_12560573_-|DUF1552-domain-containing-protein	gnl|CDD|377875	pfam07586, HXXSHH, Protein of unknown function (DUF1552). A family of proteins identified in Rhodopirellula baltica.	1.03339e-71
NC_021658.1|WP_148315039.1|12557956_12558865_-|aldo/keto-reductase	gnl|CDD|381326	cd19100, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	2.50873e-104
NC_021658.1|WP_044989478.1|12539733_12540360_+|glycoside-hydrolase-family-11-protein	gnl|CDD|366111	pfam00457, Glyco_hydro_11, Glycosyl hydrolases family 11.	5.26496e-73
NC_021658.1|WP_080682581.1|12562559_12563471_-|hypothetical-protein	gnl|CDD|333766	pfam00014, Kunitz_BPTI, Kunitz/Bovine pancreatic trypsin inhibitor domain. Indicative of a protease inhibitor, usually a serine protease inhibitor. Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure. Certain family members are similar to the tick anticoagulant peptide (TAP). This is a highly selective inhibitor of factor Xa in the blood coagulation pathways. TAP molecules are highly dipolar, and are arranged to form a twisted two- stranded antiparallel beta-sheet followed by an alpha helix.	3.38896e-18
NC_021658.1|WP_020740763.1|12540508_12541141_-|glutathione-S-transferase-family-protein	gnl|CDD|223698	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	1.25518e-31
NC_021658.1|WP_020740770.1|12550927_12553228_-|helicase	gnl|CDD|350192	cd18805, SF2_C_suv3, C-terminal helicase domain of ATP-dependent RNA helicase. The SUV3 (suppressor of Var 3) gene encodes a DNA and RNA helicase, which is localized in mitochondria and is a subunit of the degradosome complex involved in regulation of RNA surveillance and turnover. SUV3 exhibits DNA and RNA-dependent ATPase, DNA and RNA-binding and DNA and RNA unwinding activities. SUV3 is a DEAD-like helicase belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.	2.99961e-34
NC_021658.1|WP_044986884.1|12535851_12536964_-|hypothetical-protein	gnl|CDD|215598	PLN03138, PLN03138, Protein TOC75; Provisional.	0.000158188
NC_021658.1|WP_080682806.1|12533717_12534635_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187632	cd05374, 17beta-HSD-like_SDR_c, 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. 17beta-hydroxysteroid dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.33227e-47
NC_021658.1|WP_020740782.1|12566665_12568033_-|DUF1501-domain-containing-protein	gnl|CDD|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	5.48996e-20
NC_021658.1|WP_020740780.1|12563576_12565268_-|serine/threonine-protein-phosphatase	gnl|CDD|277316	cd00144, MPP_PPP_family, phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain. The PPP (phosphoprotein phosphatase) family is one of two known protein phosphatase families specific for serine and threonine. This family includes: PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6, PP7, Bsu1, RdgC, PrpE, PrpA/PrpB, and ApA4 hydrolase. The PPP catalytic domain is defined by three conserved motifs (-GDXHG-, -GDXVDRG- and -GNHE-). The PPP enzyme family is ancient with members found in all eukaryotes, and in most bacterial and archeal genomes. Dephosphorylation of phosphoserines and phosphothreonines on target proteins plays a central role in the regulation of many cellular processes. PPPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	2.12353e-39

Protein sequences

>NC_021658.1|WP_020740770.1|12550927_12553228_-|helicase
MVDASPITAVLGPTNTGKTHRAIERMLAHDSGMIGLPLRLLAREVYDRVTTRVGEARVALVTGEEKRVPRRPDYWVCTVEAMPIGLEVDFLAIDEIQLAAHDQRGHVFTERLLLSRGRRETWFLGADTMRPLMAELVPTAKLVQHPRLSRLASAGAGKLSRLPPRSAVVAFSTPQVYEIAERLRAQRGGAAVVLGALSPRTRNAQVALFQSGEVDYLVATDAIGMGLNLDVRHVAFAALRKFDGRAVRDLDPAELAQIAGRAGRHLADGTFGTVAPLSLPDGVAAAIEAHRFPPVRRLLWRNSELDWSSIDALLASLRERPRSRSLKLVDDAEDTAALMRLAEDPEVRARARGREAVALLWEVCRIPDFRKLLFESHVALLAEIYGQLSGPGAALDTDWMAARVAEIDDVGGDIDTLITRIASIRTWTYISNHGRWVRDAAAWQDRTRAIEDRLSDALHERLVQRFVERGGGARASSGARAVARGGQRRAEAEPEPVAAGHPFARIAALRALLAPGPAAPAPEDDRARWVEAIVGAPHERFSVDEAGRIAHGERPLGQLARGPTLLLPDVRLAELDDLGAGARSRVLRRLVAFARDLVEELLAPLRSPEVRALPGAARGIVYQLEQGLGTAAARDAEEQIAELAPEDRALLKAHGIEVGERVIYVQQLLRRGALERRLSLCAAWFGRGRVPACPAPGAVSVPAARGVDPKAYAAIGYPVFGTRALRADVAERVHRALASGEPAARLSSWMGCPAREAPRVAASLLG
>NC_021658.1|WP_148314423.1|12549607_12550492_+|hypothetical-protein
MSKRSVLGLVCLVAATSLAGSSSIAAEPSNHVLFYSAGSGAGCTWRPWVGIERCYNNFSTGWTHITGDGTGQLTFYNASNGKGGIGKIAGAGHFTTSWSGDGFGAGWTHLTATGTGLVLFYNAATDQGAIWKPWSGFQWRGSGFGAGWTHLASDGNGEALFYNASTGAGCTWRVWVGIQKCYTNFSTGWTHITGDGTGQLTFYNASNGKGGIGKIDGAGHFTTSWSGDGFDTGWTHLAADGAGLVLFYNAATDQGAIWKPWSGFQWKGAGFGHGLGARWTNVAGPLGLGSDHAG
>NC_021658.1|WP_020740768.1|12549142_12549520_+|hypothetical-protein
MKKLIAVAFALSSLYSASAFADGLNACNQTRETIWVAYASVEAPRLETRRQRVLIGNLQRAGGAPRMRSSDAVLPHRDARAPRRSGGLFHLRADAIAIEQKRAASIAAVDLRRQPRPRPSLPRAS
>NC_021658.1|WP_148314422.1|12546301_12546643_+|hypothetical-protein
MSKYSIVHTWAAVALVATVLLVVGSSSACALASSVEDEPVGEAVEAVVRDYPPGHVFMCVIEGYRGLEWKSMVVTADLRTCRMYPYPAPYPGEVRPAFNCYQMGSRAGCENII
>NC_021658.1|WP_020740766.1|12544290_12544773_+|hypothetical-protein
MKTIQRLAPLLAGASALSMGGGSHALAGTTSDTIEVAARSDAASACAHPRPLFGKVVAVCGDQMIAYVGDETVEILGVKTTSSRFELAYCSNGGGRKPLSLETNSEGFTLASTTYANGEHYTISHMWGTFRMSGIGFSGEKVDVQCVPFEDRRTDVRYLH
>NC_021658.1|WP_020740763.1|12540508_12541141_-|glutathione-S-transferase-family-protein
MAIVLYHHPFSRAANTVWMLEEVGVEYELKFVDIMAGDQKKEDVTKLNPMGKLPLLVDGGTVVTESAAIGLYLADRYAPGRLAPKLDDAARGTYFRWSLFAPSVIEPGSMAKAGNWEFRSGSAGWGNYDDMIATMESAISGRDFVLGKEFSMADVIFGGTIAYMLDFKMLEPRPSFTGYAERVRARPAYAKSEARNKAVMDERGLKMPGA
>NC_021658.1|WP_044989478.1|12539733_12540360_+|glycoside-hydrolase-family-11-protein
MTEAELAADQSALAINTNQTGTDGRWYTFWKDGGSVSMNLNGGGNYAVNWANGNYNFVGGKGWSTGSSSRNIGYNAGVWSTGSSNAYLTLYGWTTNPLVEYYVVDSWGSWRPPGGASAGTVTTDGGTYDLYRMQRVNAPSIIGNATFYQYWSVRRSKRATGTNSAITFSNHVNAWASKGWHLGTHNYQVMATEVFNPSSSGSSNLTVW
>NC_021658.1|WP_044986884.1|12535851_12536964_-|hypothetical-protein
MQDQTFRRLAFCVTLASWAAISCAPAESDSNSDGGGGATATGSVGSASGSGVATSSGSASGSASGSGVATSGGTTAAGTGGDNSGGSGGAEPAGGGGAGTGGWPEGAIPMGNAPVPSAGCGKATTLTTKEYTISSSGQNRVYYVDMPRNYDMNKPYRLFYTSHWIGSRYQDVKNQDFYFLKPQLEADGEQAIFVAPSSDGATWQEKDHALFDDIMAFMNENVCYDTTRVFATGFSFGGMITYSLSTNHQAEIRAAVGIAPANYNIWLPEKTRKPIAWMHTTGMGDTTCPWVNNEGQKRGAKFIALEKAEDNGCTIPDQIPTSNGAYSCYDFKDCDPEHPTRVCTFGGGHTNIDGNPNWIPIESWKFFKQF
>NC_021658.1|WP_080682806.1|12533717_12534635_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTKTILITGSSSGLGRATAKHFKIRRQFDVNVLGVLATTKALLPHFRANRSGVIVNISSGGGRVTLPLGTLYHGTKFAVEGLSESLHFELAPLGVRVKIVEPGAIKTDFMSRSLDFSNDPQLSEYQPLVQKVLAVIGPMMEQGAPPERVAESVYPATTDDSNQLRYEVGVDVVELLESRRSMDDASFLGGMRTQCALFDRRGASVHVLDEGSPKMSAMRCLPGGKPSGEARRGKGSMRFGGYKEHLARDLDHPVIVSCAVTPANRPEEEGAAPMAEDVQRQRPRLVELHIDRAYVNSLWQSYSGR
>NC_021658.1|WP_020740758.1|12532864_12533713_+|thioredoxin-domain-containing-protein
MRTSTRSPLAFPLRAAATALALVLTAACSNAPDGAAPIEEVAPPAAAPRAAAQKPAAAKVAAQKPAAANAAELPAIHGPGGACDPEPGGDCGSCDGAGDHGPEHMIGEEVEQLDIRNAPTRGPANAPVTLVVFSDFQCPFCSKFAGVLDQLEQEYPGKLRLAVKHRPLPFHKQARVAARASLAAHAQGKFWEYQAALFDKAQGALDKAGLEERAADLGLDVARFARDMQSPALEAQVAADFEEGDRLAIEGTPTLFVNGRRVMGAQPIGVLRAAIDRALAGK
>NC_021658.1|WP_020740772.1|12556453_12556612_+|hypothetical-protein
MSWEEFQANAHRDNERGLTIIDGFERGLDDAELRAVYERYVQTGALVVNVPR
>NC_021658.1|WP_187345773.1|12556892_12557060_-|hypothetical-protein
MVSDIALAVVVHGATATPTACSDSVSSRACAARRSAALIRPKCSRRAVRIRPSST
>NC_021658.1|WP_187345774.1|12557074_12557773_+|hypothetical-protein
MAQRVLYDARHQRKDHPMKMNGLRVVTSIACFAVLAALNAVGCAEVDDVAHEEIGQEARNHGISRVVRTTNDLGQTQLDLLDTNGIPMGELRYERSNTLMNLRLSWGGDAYDVTVDGPPGQARTSILVNDVPVVDPQDSTGFDRMPLSIKPALDLAASLVLDAGLEGAPAEEEEIGATPFDGAQDKHPAALECWACVTSTWCWITTRNSQAKIVGHWDPRPICVEEVWGCGC
>NC_021658.1|WP_148315039.1|12557956_12558865_-|aldo/keto-reductase
MPTRPLGRTGVNVSLLGLGGYHMAVPDDEQESLRIVRFAIDHGVTFLDNCWDYHDGKSEERMGKALQDGYRQKVFLMTKLDGRDRASAEAQLEQSLRRLRTDVIDLVQMHEIIRRSDPEKIFGPGGAMEALVAAKKAGKIRFIGFTGHKDPDIHLAMLKMAERQGVPLDTVQMPLNVLDPHYRSFEKNVLPALTQQGIGVLGMKPFASGEIAKTGAVSPMDCLHYPMSLPTSVVITGCDSMGILKQAIKAAYTFQPLSSQRVSEILARTAPLGAKGEHEQFKTTERFDGTTKNPHWMTSAKI
>NC_021658.1|WP_148314425.1|12559163_12560573_-|DUF1552-domain-containing-protein
MNRRTFLRGACGVMLGLPFLESLRARDAKAGPEAAPRRFIAFFMCNGVNMDRFFPSTRYGALTDASFGADRAIAPLASYRDKLLIPRGIHMAPRGFGWDPSAGDDHAKGVGCKLTAQPLVQGSQYAAGISLDQFIANKLNPPGTPALTLMVGARVPNVRGHISYSGSEQPVSGENNPWLAYQDLIGVTNVEDEALERLTKRRQSVLDLVGAEYEGLLKKKLSKADRDKLEMHFQTVRDLEVGMGDAGLIPRELPPARAAEIEAVDPATVSFDAEFKTIGRMQMDILALAIATRATRSATLQWGSGAYGPIFKWDGMNHEYNHHKLSHGNTKDDDSGSVVDGYEEMLFDIDRWFIGEYVYLLDRLAGYDEGGTSVLDNSAVVFMNELSNGKIHDFRDLPYIIAGSCGGYFKTGQYIKVTRQQNTLQDEDAPHNKLLTTLANAVGCTAEGGGPIENFGAFGEPGEFDELKA
>NC_021658.1|WP_148314426.1|12560569_12562294_-|DUF1592-domain-containing-protein
MNRRTPRMLLVALALSSAAACSGPNGDGGTGAGDGGTGAGDGGSGAGDGGSGAGVQCAPGVTAPGPTPRLTRLTHAQYDNSIRDLFGKDMKASASFLADPAFEGFDNNAKGLVVSDRLARDYRRAAEAIAADVVVDQAVLGDILPCAPEGDGAACARQLIRELGKRVYRRPLSAEQEAAYVAAYARGDGLFESGTPFEQGVRHVIEAMLQSPHFLYRVELSEELDGEQIIPLDGYEVATRLSYLLWNSLPDDALLAAAERGALGSPEGIEAEARRMVDDPKAVSALDDFHRQWLHMSRYADLSKDPALYEGFDASVSSAMLAETQAFIRHVVLEMEGDYRTLMTAPVGFVNDKLAPIYGVEGSFTSELVETPLDPASRAGLLTQAGFLASHAFARETSPIHRGVFIQRQILCADLPDPPANIDTQLPPKQGEIRTTRDQVEAHTSPKACSSCHGMINPPGFAFEHYDAVGRYREDEGGEPIDATGTMAVGEAEIRFDGAVDLVKQLAESPVAERCYLTNWYRYGNARQLSREDACTIDDLDAKLGASGYNIKELLVALTQTKTFRYRAVEEVGQ
>NC_021658.1|WP_080682581.1|12562559_12563471_-|hypothetical-protein
MNTLRSIAFSSGGRGRAGCNVSGLRRRFSFGLGLLTSLLLAAGCSGADAGGDGGAGGAGGGGPVTGSGGGGGPVTSSGAGGELPNRCSLPQDPGPCDGAIQRYWHDPSSGVCVPFIYGGGGGGENRFESLQACQEACQGNVPDMAACAAPGDCVLASPRCCAACNPNDAHAFVAVHRDSTTDFWNTLGCGDVACAPCPEVSEAESTGQYFAAACEAGRCVVLDVRESPLTECAQDADCALRDGVGCCEECSGKGIVALNQSADIESIVCPEGFGACPPCAPVYPEGMTAVCLEGRCQPKLSSP
>NC_021658.1|WP_020740780.1|12563576_12565268_-|serine/threonine-protein-phosphatase
MMTFSPDPRVAEQQMHAIIYYLTGFGYIDGELDPTEKSFIRGHIQELVQQRARDALGDEAQANQDVIARWTKHFHEVFSEIDHQIQGLFTESVSDGEDPKDFVLAKIKLRCFELLDGFDDDNREALLATVDGLMLADGVIHPSEEKFRDELSALLALAGEIDDLEIEPIEQGAVVIDPATRKQARELDHPFFKAFEWDYATDPATFAEQAKVDLDLMRRFEEKLAEQRARGAGRLDGAADLASFAGQAPFLDGHVYVASPDPAHEVELLVVGDLHGCYSCLKAALMQADFFAKLQAYREDPAHNPRIMLVFLGDYIDRGRFSYNGILRTVMQLFLAAPDNVFVLRGNHEYYVELNGRVLAPVRPSEAMSSLAAIAPNEVFAAYMRLFEALPNMLVFDRILFVHAGIPRDDTLAARWQSVSSLNDPEIRFQMLWSDPSEVDAIPAELQKSTARFPFGKRQFKSFMQKLGCTTLIRGHERIPEGFRVVYDDPDGVLLTLFSAGGRTNDDLPKASNYREVTPMALTIRYKGGVSQLTPFVIEYERYNDPKYNAFFREQLPSLELSV
>NC_021658.1|WP_020740781.1|12565397_12566669_-|cytochrome-c
MTPLRRAAPLAALAPARLAALAPARLVALARLTALALACLAVLALAGCASQAAPPRPPLAVRPVAWPAPRELGPVRAVADDGDRVVLFHDGAAAVFVNGALARVERAPHRWVGAAVVPAPDGYGTWIVGADAEGRLLRLPSRGAFEPVADHYGLERAAVRAAAGLGLGGGAAFALDGEIAVADGERVTRYATGPLAAFAAGGGRVAFALGGEEVLALDVAPRALRSYPLEADGPAPLLAVTGAGALLAATPAALYAEDGAGVLRLRLRASAALHGLAVSGERVWFADGGELGVLDASGARATRGARLPEAGRLIGSPSGDVWLLAAGALRRFAADDGGAGPAWDDIAPVFDRACARCHRPRGEGGVDLSTRAAWASLREAIARRVVEERTMPPPGHALSEADRARIRGFVERLAPPARPSARP
>NC_021658.1|WP_020740782.1|12566665_12568033_-|DUF1501-domain-containing-protein
MAPGLPRRALLQAAAGAALSGVLGLPARALAAHANAAQDEFFLFIHASGGWDVTLWADPRNESKGLVTPATTDNTDTAPLRLWVDAPAAGGAKSFAPVTPKGSSLTFGPGIGALADLHDRLCIVNGLAMNTVSHPDGTAFATTGRHLSGGRVMASSLDAICASELGASQTFPAVSVQFPSAFVGDRLDRRAVPLTVGDIGTISRSLARARHYDTDEDRAAVTALLSEEARSLAARSRYTDALNGFAIQSEALGRMLNAGLQDVFSRGKLIQAHPELDHKARFARQAAVNAAFAIEAMRRNVVRCVSFACDGFDTHTSNYRQHAATQQELFDLIAALLGSLDKTPHPTRAGKKLSDHTHILVTSDFCRTPQLNTAMGRDHYPNNSAMVISPRFRGGISFGKTDPEQLLPAPAKTFQGGPRPIAPPDLLATFLFAFGIPPLAHLRDGEVVPELLRRS

Crispr_ID: NC_021658_57

• CRISPR_ID: NC_021658_57
• CRISPR_location: 12646297-12646447
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_57

Consensus_repeat	Method
GCCGCACCGCTCGTCGGACCGGCAGTCGGCGCTGCAGCCGTCGCCGTCC	CRISPRCasFinder

spacers of NC_021658_57

>57.1|12646346|53|NC_021658|CRISPRCasFinder
CGCGCGTTGCCGTCGTCGCAGACCTCCTCCAGCGCGGGATCGACGACCCCGTC

CRISPR arrays and Neighbor proteins around NC_021658_57

CRISPR arrays

The CRISPR arrays of NC_021658_57

>merge|NC_021658|57|12646297-12646447|CRISPRCasFinder
GCCGCACCGCTCGTCGGACCGGCAGTCGGCGCTGCAGCCGTCGCCGTCCCGCGCGTTGCCGTCGTCGCAGACCTCCTCCAGCGCGGGATCGACGACCCCGTCGCCGCACTGCTCGTCGGACCGGCAGTCGGCGCTGCAGCCGTCGCCGTCC

>NC_021658|57|50|12646297-12646447|CRISPRCasFinder
GCCGCACCGCTCGTCGGACCGGCAGTCGGCGCTGCAGCCGTCGCCGTCC	CGCGCGTTGCCGTCGTCGCAGACCTCCTCCAGCGCGGGATCGACGACCCCGTC
GCCGCACTGCTCGTCGGACCGGCAGTCGGCGCTGCAGCCGTCGCCGTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020740836.1|12639899_12641285_+|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225114
NC_021658.1|WP_148314436.1|12642252_12643260_-|calcium/sodium-antiporter	unknown	unknown	gnl|CDD|273039
NC_021658.1|WP_044986901.1|12655831_12656272_-|response-regulator	unknown	unknown	gnl|CDD|225114
NC_021658.1|WP_148314435.1|12641485_12642184_+|hypothetical-protein	unknown	unknown	gnl|CDD|308978
NC_021658.1|WP_020740849.1|12666921_12667605_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|222854
NC_021658.1|WP_148314434.1|12637765_12638128_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020740835.1|12638439_12639903_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_021658.1|WP_187345776.1|12668380_12669445_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_021658.1|WP_080682807.1|12633109_12634030_-|transposase	unknown	unknown	gnl|CDD|224854
NC_021658.1|WP_044986903.1|12658201_12658624_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NC_021658.1|WP_049949792.1|12649099_12651289_-|response-regulator	unknown	unknown	gnl|CDD|223715
NC_021658.1|WP_044986905.1|12659047_12662017_+|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|379311
NC_021658.1|WP_063752169.1|12634422_12635379_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020740848.1|12666302_12666971_-|hypothetical-protein	unknown	unknown	gnl|CDD|237865
NC_021658.1|WP_020740847.1|12662832_12665727_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|226702
NC_021658.1|WP_020740846.1|12662132_12662555_-|response-regulator	unknown	unknown	gnl|CDD|381108
NC_021658.1|WP_020740833.1|12636619_12636940_+|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|367760
NC_021658.1|WP_044989497.1|12643354_12644314_-|PEGA-domain-containing-protein	unknown	unknown	gnl|CDD|285503
NC_021658.1|WP_049949790.1|12635534_12636584_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176109
NC_021658.1|WP_020740840.1|12647010_12648252_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|283431

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020740836.1|12639899_12641285_+|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	0
NC_021658.1|WP_148314436.1|12642252_12643260_-|calcium/sodium-antiporter	gnl|CDD|273039	TIGR00367, Uncharacterized_membrane_protein_MJ0091, K+-dependent Na+/Ca+ exchanger related-protein. This model models a family of bacterial and archaeal proteins that is homologous, except for lacking a central region of ~ 250 amino acids and an N-terminal region of > 100 residues, to a functionally proven potassium-dependent sodium-calcium exchanger of the rat. [Unknown function, General].	7.16009e-66
NC_021658.1|WP_044986901.1|12655831_12656272_-|response-regulator	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	7.42399e-36
NC_021658.1|WP_148314435.1|12641485_12642184_+|hypothetical-protein	gnl|CDD|308978	pfam03682, UPF0158, Uncharacterized protein family (UPF0158).	4.99894e-05
NC_021658.1|WP_020740849.1|12666921_12667605_-|AAA-family-ATPase	gnl|CDD|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	2.58956e-40
NC_021658.1|WP_020740835.1|12638439_12639903_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.18449e-50
NC_021658.1|WP_080682807.1|12633109_12634030_-|transposase	gnl|CDD|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000151306
NC_021658.1|WP_044986903.1|12658201_12658624_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	7.92357e-31
NC_021658.1|WP_049949792.1|12649099_12651289_-|response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.12002e-50
NC_021658.1|WP_044986905.1|12659047_12662017_+|HEAT-repeat-domain-containing-protein	gnl|CDD|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	3.81353e-05
NC_021658.1|WP_020740847.1|12662832_12665727_-|PAS-domain-S-box-protein	gnl|CDD|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	1.00149e-52
NC_021658.1|WP_187345776.1|12668380_12669445_+|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	3.39157e-09
NC_021658.1|WP_020740848.1|12666302_12666971_-|hypothetical-protein	gnl|CDD|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	1.03418e-05
NC_021658.1|WP_020740846.1|12662132_12662555_-|response-regulator	gnl|CDD|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	6.75643e-55
NC_021658.1|WP_020740833.1|12636619_12636940_+|antibiotic-biosynthesis-monooxygenase	gnl|CDD|367760	pfam03992, ABM, Antibiotic biosynthesis monooxygenase. This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.	1.22071e-07
NC_021658.1|WP_044989497.1|12643354_12644314_-|PEGA-domain-containing-protein	gnl|CDD|285503	pfam08308, PEGA, PEGA domain. This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteristic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	9.99859e-05
NC_021658.1|WP_049949790.1|12635534_12636584_-|LysR-family-transcriptional-regulator	gnl|CDD|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.3e-66
NC_021658.1|WP_020740840.1|12647010_12648252_+|VWA-domain-containing-protein	gnl|CDD|283431	pfam05762, VWA_CoxE, VWA domain containing CoxE-like protein. This family is annotated by SMART as containing a VWA (von Willebrand factor type A) domain. The exact function of this family is unknown. It is found as part of a CO oxidising (Cox) system operon is several bacteria.	4.15185e-33

Protein sequences

>NC_021658.1|WP_044989497.1|12643354_12644314_-|PEGA-domain-containing-protein
MSLALLAAVAAPARAQAPPALPPWHQGVSEERKQRAYALFQEARDLHRRMMLAEAREKYQEALASWEHPELRLYLARVLRSIGLPLLAHESLRLSLQWGPGALTPEQEQEARSTLRALVQHELAAIEIRCDERGARVLLDGKPWFVGPGAARRMITPGEHVITARKEGYFTVVKPVLVLAGKEASGHVTLSVDAVIAERRWAPWVPWATLGAGAALGVAGAGLWWQADVHYRDADRRLGGGCDPWCTPSARDAYDASVIENRLAIGAFVAGGAAMITGTVLLLMNGPQSHRTDDRGGVRIELLPVLPGDVAGLSARLAL
>NC_021658.1|WP_148314436.1|12642252_12643260_-|calcium/sodium-antiporter
MLLYVAQLVLGGGLLYFGAEWLVKGSAGLALAFGLRPLVVGLTVVAYGTSAPELTVSLAAVLEGRGALALGNAIGSNIANLGLILGVTALISPPRVEGGLIWREIPFLVGTAAVVPLLLLDGTMSRLEGAALCATSVGYSAWVIRSARGGPARVSPPRPSPDERGALLAAREMEADAERAGAPGGGGKLRLAVITVVGLGLLILGGKVFVDGAVGVALGVGMSERLVGLTIVAVGTSLPELATSVIAALRGHSDIAVGNVVGSNIFNVLIILGAAALARPLEGSPGAMAVDLIALGALTALAAIAMRTERVLRRAEGAALLAMYVAFVVALILAG
>NC_021658.1|WP_148314435.1|12641485_12642184_+|hypothetical-protein
MRAAYGPRANMSTTTTESAAAGRRVPVDWSALASAFDNTAQHIRYFLHLETGALIRLVDGLADPDTRVRVEADPACVRVEAIAARDQYRWLQAFIPTVDDIELQVLLLQCLQGPGSFRRFKAVLSGRPDQLRRWRVFRMERIRAAILDWFGARGLVPASFEHAWPGAGAESMRSRAVDSARQQLHAMTSDLAPGDLHALTALAEFLRATRSGSHAPLVSSRRDAERPDGLGP
>NC_021658.1|WP_020740836.1|12639899_12641285_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MTGRVLIVDDERGVCELLDAGLKKRGFRTAWRTSAAEAFELLGVEDFDVVVTDMTMRGMNGLELCERIVQNRPDLPVIVITAFGSLDTATSAIRAGAYDFVTKPFELDALRLTVERALRHRALREEVRRLRRAVADVRGYEQILSSSPVMRSVFDLLDRVADSDTSILITGESGTGKELVARAVHQRSRRSEGAFVAVNCAAVPDALLESELFGHARGAFTDAKGARSGLFARAHGGTLFLDEIGELPIGLQPKLLRALQERVVRPVGADEETPVDVRLIAATNRDLETAIEERRFREDLYYRINVVHVDLPPLRSRGADVLLLAQHFLEHFAAVKARPIEGLSAPAAEKLMAYAWPGNVRELQNCIERAVALARYDHITVDDLPEKIRTYARSHVLVSSDDPTELVPMEEVERRYILRVLEVVGGNKSQAAQILGFDRATLYRKLERYGMRGGRSSDPKP
>NC_021658.1|WP_020740835.1|12638439_12639903_+|HAMP-domain-containing-histidine-kinase
MKLARKLTLALVFGVFLVLALSAYVQIRREARIFENDVQRDHHTMGRVLAAAVTEVWRSEGQARALRLVDDANERERQVDIRWVWLDERASEAHRPRLAPELLVPVSMGQTVVHRIPRKDADVLITCMPVPVPGDRVGALLLSESLAGARRTIRSMILSTTVTTAALALVCGLLTTSLGVGLVGRPMRTLIDQARRIGAGDLSRRLSLHQKDEIGELGREMNAMCDRLAAANQKLESEAAARLAALQQLRHAERLATVGKLASGIAHELGAPLQVVAGRARMLVDGDVSGDEVPTNGQIILEQAQRMTQIIRQLLDFARRRSAEKQETPLGSVLRSTFTMLRPLAEKQGVTIVQEGDTSALMVHADADQLQQALTNVVVNAIQAMPSGGTLTVGVRAERASPPADQGGGVEGDYVALSVRDQGGGMPADILEHIFEPFFTTKPVGEGTGLGLSVTYGIIKEHGGWIHADSRVDSGSCFTMFLPQWKP
>NC_021658.1|WP_148314434.1|12637765_12638128_+|hypothetical-protein
MISTPPEGPNTVRSHRLPSPRQPQRRASPWARRSVAALLALLVASAALAACSRGAGAPKHREAAPERDRACTDPERPRAYFYPAENRTDYAPDDPWKDGCAMLVPDHLFCCPEKAAEKPR
>NC_021658.1|WP_020740833.1|12636619_12636940_+|antibiotic-biosynthesis-monooxygenase
MIIEYIRYVIPADQEQAFLSAYRDAAAELRGSEHCLDYEISRCVEDPASFVVRIRWGSLEGHLQGFRKAASFPSFFAKVKPFYERIQEMRHYASTDIAGAGGGASG
>NC_021658.1|WP_049949790.1|12635534_12636584_-|LysR-family-transcriptional-regulator
MRRRARSGEQGYVAAALPSNRQSARPFIDGVYGLACYPSIMRLQSVDTHLVVALHALLQEKSVTRAARRVGVTQPSMSHALSRLRAHFGDPLLVQVGRRMTLSERARDLLPRAAEAVERLEQVFSPAERFDPGRSGRTFRLVATDNLELLVLPALARLLAAEAPHVDVRCRNIPADFAELLRSGELDGKLGRGGPVPDGCRSMLLAAERLVCVMRRGHPASRKPLTAARYAACEHLMVSPHGEDRGVVDRELAARGLRRRVTLTVSHFLVAPFIISGSDLLLTVSARVAGAVASKLDLVVRPCPVEIAGYALTLVWAERSERDEGHRWLRDAMARAVACEPVEGPGASG
>NC_021658.1|WP_063752169.1|12634422_12635379_-|hypothetical-protein
MPCIRAAALIALLTLTSGCAARSQPASPVPLEIPVAPAQRTTEAQAAGNAAPGGVVLVWGSVGDGAPRTWHLAEGGAVSREEPGIVVATRRGEWRWETREEQVATSACEMGLGGMREPGEGTATRAALVLRGKGERQEVLSPPDGDESNEIHHTAALIGSVGPYLFIEERTYTDLCGAHGFEGAAFVAWDAERRGAVDLLAEVRGVTGLQSAAEALLDDGEDGAEATGQERDAPELVRIAPAYDERGALRLTAQLARSACYACSDGAWSSYSRSAVVPVERTPARLAAWASPPPDVRAFLERTPGVRLGGWSQAGQEE
>NC_021658.1|WP_080682807.1|12633109_12634030_-|transposase
MSQPRQIAPGATYLLTRRVMRRHFLLRPDAAINQLLVYALAVSARRYGIEVHALCAMSTHLHLVVTDVQGVLPRFLQFYHRLIALGTKVLRQWEGPVWDHEATSVVQLVTQAAVVEKIAYVLANPVAAGLVRHAREWPGVKVDVGDLGRGVLHALRPSAYLNPKNPQWVEQATLSLALPPTIEQENAEAFRLQVAAELERQEAQAHAEAEQQGRRFSGAERASEISPYERATSREELGARNPTFAVGRNQGDAWRTAKAAVCAFRISYRTALKQWCAGVRNAVFPVGTWWMRTFHGARVNDATLAA
>NC_021658.1|WP_020740840.1|12647010_12648252_+|VWA-domain-containing-protein
MSARKPGKAPPPPSPAAAPDDLSDADRDALLRWRLALGPEAERVDPRLSLGGLGGAAPALHVDPRRLGDLDKALSFIYDERAGNLGGSRPYVPEWLSAVREFFSHDIVALVQKDAIERKGLTQLLFEPETLPFLEKNVELVATLMSARGLIPDAARETARQIVREVVEEVRRALESEVRTAVLGALRRNTTSPLRVLRNLDWKRTIRKNLKGWDADRRRIVPDKLYFWANQTRRHEWDVAILVDQSGSMGESVVYSSIMAAIFASLDVLRTRLLFFDTEVVDVTPMLVDPVDVLFTAQLGGGTDINRAVAYAQANFIERPEKTLLILITDLFEGGNAEELVARMRQLADSKVKSICLLALSDSGKPSYDHEMAQKLAAVGTPCFGCTPKLLVKVVERLMKGQDLGPLLEAEAR
>NC_021658.1|WP_049949792.1|12649099_12651289_-|response-regulator
MSTAPATTSILLVDDQPENLAALKAILVDESYRLVTAASGRDALLRILSEDFAVILLDVRLPDIDGFEVASLVKQRERSRHTPIIFLTAATDDLSAIYRAYAVGGVDYLLKPLEPEVVQAKVAVFVELHRRGEQIKEQAELLRKAEQRRRDAEVEDLRRAAQARYQNLADAIPQCVFTAKLDGSVDYVSSRWLEYTGLAFEALRGWGWQAAVHPNDLNQFVSKWRRCIESGEPLQGECRLRSRHGAYRWHLCQAVPERDVWKRVVGWLGSFTDIDDSKRHEQERIHLLTRERAARAEAEAAVRRSELLAEASSAFSASLDEASVAAALVRIAAERICTWCVLDLRKEGGACRVAAAHRSRDAARFAERFGPRELPLAEGGVGAVLTSGRPDLRVECAPRDVARALDIDDPGEIQELGASSYLCVPLVTRGNVLGALSMVWVEPGERFEPPDFAVALDVAQRAALCLENARLLRLTREAVQIREDFVAVASHELRTPLSALVLQIQGLTRAIGRADGGLPAEQALAKLAQAEAQIERLTRLIDTLLDVTRINSGQLELSLEDVDLCDVAREVAGRLESELERAGCSLDLDVPESAIGRWDRLRIDQVITNLLTNAIKYGRGKPIQMRISVDGKSAVLQVMDQGIGIAQEYIARIFGRFERAAPTSSYGGLGVGLYIVDQILRAHGGSIQVESAPGMGARFQVALPLPPRAAGSPGPRGERPGSPLTGPAG
>NC_021658.1|WP_044986901.1|12655831_12656272_-|response-regulator
MSSSSPNVLIVEDDDDLGRFVVDIATDHGYQATHVADALSGLRLLPSGKFELLITDIRMPGMDGIELIARAKQHDPSLAVIAITAFGSVETGMRALRVGASDYLSKPFRSDELSSRMRRALERRAREIEHARLQRQVEEVLRRGKS
>NC_021658.1|WP_044986903.1|12658201_12658624_-|helix-turn-helix-transcriptional-regulator
MKRSCQHLCQRFQTAMSVLAKPWNGLIIATLEEGALRFGEIGERLDAISDRMLSSRLKELEALGLVERRVLPGPPVRVEYELTAAGRGFGEVAQAISRWGEMLADSAARAGGAKGGARGAKPGPAAKRARPRAAQPRKGP
>NC_021658.1|WP_044986905.1|12659047_12662017_+|HEAT-repeat-domain-containing-protein
MSAAPGEVQRIGAAELRAFIQDAGELKKGTLLYDGGQLLNLARYENKLFCEARGSGASPYKVTLVYSDAPAPGFKGRCTCPARTFNTAFCKHAAALLVAWARAPESFAVSDAAPPGAPGGETARRSVKKGAANAQALMKSGVEQVSTLVRELGVAGVATIGADRIEQMEKLAEGLRENRLRRLSARTLDLAALLRGQAAGSAPAARGPQAAAGHPAGARRGALPAVAYANLIADLLLTARKLEKHLAGEPLDDRHVEELVGKTWKASDRKPADGLTLVEYAFSTRTTSDDFVIRESRFLDLESGRHFSEKQILPAFMAKRTEPKRSFAGEVLAGARATTYPGYPPLRLDFTDLGDKRSLDAGALDAVLARALPDVGAALAALQEHRKDVFAPDLVPVAVRIDTLFARGARLSAVDDKGEALHLPDDPALEERLAGSLRDARLRALLGDVGIDAALPTLWPLAAVVEGPLGLSLLPVVEQGAAARSGPLEGSAWNAAAREAGASPAAIALGEVREELADALATGLTGLSARVTDPLAERLRDLRLEKQAALLQGLPQRPDPADRLDDFIKLYQVLEMALVRLAGATHVDREGGAIERVPTYESVAVARPDETLPPDEVARRRAAGAMNRYVAAVHHARYYASLPPGELVGSIFPIWADGTATPTIARTFAPLGAEAIAAAEKALTVKAGRVAKLTAVRVLQAVVQHGGPARAEAAAMLGRVAEHAKDAGLRALARDALDVADSTGPGGAAVRARRAARMERVQELAKALGAAPTKEERLEALKALAELGDLAALPALRRAFYADAARGVREEAAYALAQLGDVEMVETFARMLASRGEDDREAKIAAYALGYLGDVRGLSELLSAYAEGYKPGIVADAIRAFGPVALAPLVDLIEARPELAKRAAALDALKKTDDTAVAGCLLERIEARRGDADFAEKAQLYLKLADVHPHSRREVATAIAAALAGAEGKEAQAAIKAAQKALGVVKRSK
>NC_021658.1|WP_020740846.1|12662132_12662555_-|response-regulator
MSVEEKLLNILLVEDDEVDVMNVRRAFKRNNISNPLWVAGNGVEALEMLRSGSIPVERRLILLDLNMPKMNGIEFLRELRADPDLVATSVVVLTTSNDDRDKVGAFNLNVAGYLLKPVTFLSFVELMAALNKYWRLVELP
>NC_021658.1|WP_020740847.1|12662832_12665727_-|PAS-domain-S-box-protein
MTQHVRDEGTTARGLNQKEAQVTSDAGRSVHAMFMEAPTAIAVFRGPDWVIDFTNRLAQRLFRDRTAVGRRLFQCAPELAGSRVAELLERAYGSGQPAAACELLILLDRGAGDGALAEGYFNVTLQPIPAGAGGAHSVVLFAVEVTDQVLARRRIEQLAEQVEHERHKLEQIIQQMPHAVYIADAPSGHLVTGNAQGAAQLGRPFVASEDVEAYSAAYRGFHGDGRPYAPHEWPLARAVLSGELVRAEPVEMLRADGTRAIIEYSAAPIRDASGQIVAGVAVGVDATERIRALREEQRRSEQLKGLAEASLAVNSATSLDRMLAEITERARALIGAHQSVIRMTDDQSWAHAVNAVSLSDKYAAYRGYDARSEGSGIYSLVCETNKPVRMTQAELEAHPAWRGFSGEAARHPPLRGWLAAPLIGRDGRNLGLVQLSDKEEGEFTGDDESILVQLAQLASVAIENTRLREEALAAEKRFRSMVEATAVVVWRTDPRGHVVEDSPSWRGFTGQRYEEWVGYGWLDAVHPDDRARAGAAWRGAVASKTRYEVEYRLRRRDGSWADTVARGVPLIADDGSIYEWVGCNVDVSDIRRAEEAFRVQHRLVRTIAENATLGLFMMDAHQRCTFMNPAAEKITGFTFDEIQALDRPLHELVHHTRPDGSRYPMEECPIDRALPRKSQEQGEDVFVRKDGSFYHVAFTASPILDGDVPVGTVIEIRDITEQKRAEAERERLIAALERSNKELDQFAYVASHDLKAPLRGIANLTQWIEEDLSGTLEGESREHMSLLRGRVRRMEALIDGILDYSRAGRVRHASEPVDVGQILADVVELIAPPSEASVEVAPGLPVLRTERIPLQQVFMNLVSNALKHARRADARVRIGHRDAGLLHEFFVEDNGPGIAPEFHERVWGLFQTLEARDKVEGTGIGLSVVKKIVESRGGRIWIESSPGQGAIFRFTWQKRDPSDP
>NC_021658.1|WP_020740848.1|12666302_12666971_-|hypothetical-protein
MAKKQVAVSLRKPPSPEKVEAFVAGGEGGAPAPDAVTSRPAADRRARDDKDDKTAEAKQERAPEARAPEAPPSAEPPPSVAPPPQASAAAEPQPLATTSEPPAVPPVLVGNDGRARRAVTVYLPDPLADRLLLHCIEHDRDVSNLVGEAVEVHLDKRLGPAPVSAAPAGGGAAAAHEAAPPGPSYRAEPFRAADTRPTGRVGRMVQVGRVLMTLWRQRPRAS
>NC_021658.1|WP_020740849.1|12666921_12667605_-|AAA-family-ATPase
MIIALTGQKGGIGKSTTAVSLAVAALAKGRRVLLVDADPQGTVRTWGDVAAEAGHETPTVMAMGASMHKPGQLPDVAAAYDLTVIDCPPRHGEIARSALMVADVAIYPCGPTAADAWALTAAIEVFREAAALRSALKGCILITRKQGRTALGKSARAVLETSGLPVLATELGYRIAYQESLACGQGVTGYAPRDAAAKEISHLLEELEKLHHGEKASRGLAKKAAVA
>NC_021658.1|WP_187345776.1|12668380_12669445_+|CHAT-domain-containing-protein
MEGELRAVRFRDKIGLKASHAVRPDDLVRLLRQEQPTVVHFSGHGSHDGIILRTDSGYLAVTGESLARLFRDRGVRLVVLNACFSQEQARLLVGAVDAVVGTTAAVGDEAARRFSTAFYRTLGDGYSTRDAFRDGGDAVAVHSLEDVFLAYGDLEAVLARGDVAADAAPAETPTSLVTTADLLREIGRLTHDEKLVFRAILKASPEVHKNVYREFFRASNRIGGNERDGYFFRILEKTRLSRETVTAAVGRLLAVGLVNEQHLTDVLYSPTPPVLAIVNRSPAAILSTLYSKDETDSPEVEVFFGGVYYKDGKPHLYRDNDDVPLEGPFRLNERSDAVTYFSEGRIVTKTPGDG

Crispr_ID: NC_021658_58

• CRISPR_ID: NC_021658_58
• CRISPR_location: 12836833-12836921
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_58

Consensus_repeat	Method
GGACAGGACAGCGCTCCTCCTCGGCAGGC	CRISPRCasFinder

spacers of NC_021658_58

>58.1|12836862|31|NC_021658|CRISPRCasFinder
CGTGGCGTCGTCCGATCCGGCGCTCTCTCCG

CRISPR arrays and Neighbor proteins around NC_021658_58

CRISPR arrays

The CRISPR arrays of NC_021658_58

>merge|NC_021658|58|12836833-12836921|CRISPRCasFinder
GGACAGGACAGCGCTCCTCCTCGGCAGGCCGTGGCGTCGTCCGATCCGGCGCTCTCTCCGGGACAGGACAGCGCTCCTCCTCGGCAGGC

>NC_021658|58|51|12836833-12836921|CRISPRCasFinder
GGACAGGACAGCGCTCCTCCTCGGCAGGC	CGTGGCGTCGTCCGATCCGGCGCTCTCTCCG
GGACAGGACAGCGCTCCTCCTCGGCAGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_148315046.1|12822802_12823927_+|hypothetical-protein	unknown	unknown	gnl|CDD|273935
NC_021658.1|WP_020740965.1|12840177_12840558_-|30S-ribosomal-protein-S13	unknown	unknown	gnl|CDD|235358
NC_021658.1|WP_049949799.1|12826312_12827866_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020740964.1|12839746_12840157_-|30S-ribosomal-protein-S11	unknown	unknown	gnl|CDD|180007
NC_021658.1|WP_044986939.1|12820983_12822687_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020740966.1|12840749_12841001_-|translation-initiation-factor-IF-1	unknown	unknown	gnl|CDD|178954
NC_021658.1|WP_020740969.1|12843022_12843514_-|50S-ribosomal-protein-L15	unknown	unknown	gnl|CDD|235523
NC_021658.1|WP_012240549.1|12840601_12840718_-|50S-ribosomal-protein-L36	unknown	unknown	gnl|CDD|179039
NC_021658.1|WP_044986941.1|12832954_12834202_-|transcription-termination-factor-Rho	unknown	unknown	gnl|CDD|236490
NC_021658.1|WP_020740968.1|12841649_12842978_-|preprotein-translocase-subunit-SecY	unknown	unknown	gnl|CDD|236412
NC_021658.1|WP_020740967.1|12840997_12841639_-|adenylate-kinase	unknown	unknown	gnl|CDD|234711
NC_021658.1|WP_020740957.1|12827924_12829604_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|236901
NC_021658.1|WP_020740963.1|12839105_12839735_-|30S-ribosomal-protein-S4	unknown	unknown	gnl|CDD|235411
NC_021658.1|WP_063752086.1|12830735_12832838_-|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NC_021658.1|WP_020740962.1|12837856_12838897_-|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl|CDD|235359
NC_021658.1|WP_044989545.1|12820496_12820790_+|glutaredoxin-3	unknown	unknown	gnl|CDD|239510
NC_021658.1|WP_020740958.1|12829600_12830686_-|(Fe-S)-binding-protein	unknown	unknown	gnl|CDD|223325
NC_021658.1|WP_012240542.1|12834589_12834868_+|acylphosphatase	unknown	unknown	gnl|CDD|224174
NC_021658.1|WP_049949800.1|12837317_12837836_-|50S-ribosomal-protein-L17	unknown	unknown	gnl|CDD|235522
NC_021658.1|WP_020740956.1|12824092_12826060_+|acetate--CoA-ligase	unknown	unknown	gnl|CDD|234677

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_148315046.1|12822802_12823927_+|hypothetical-protein	gnl|CDD|273935	TIGR02031, Magnesium-chelatase_67_kDa_subunit, magnesium chelatase ATPase subunit D. This model represents one of two ATPase subunits of the trimeric magnesium chelatase responsible for insertion of magnesium ion into protoporphyrin IX. This is an essential step in the biosynthesis of both chlorophyll and bacteriochlorophyll. This subunit is found in green plants, photosynthetic algae, cyanobacteria and other photosynthetic bacteria. Unlike subunit I (TIGR02030), this subunit is not found in archaea. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll].	0.00251046
NC_021658.1|WP_020740965.1|12840177_12840558_-|30S-ribosomal-protein-S13	gnl|CDD|235358	PRK05179, rpsM, 30S ribosomal protein S13; Validated.	2.80884e-74
NC_021658.1|WP_049949799.1|12826312_12827866_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.6965e-81
NC_021658.1|WP_020740964.1|12839746_12840157_-|30S-ribosomal-protein-S11	gnl|CDD|180007	PRK05309, PRK05309, 30S ribosomal protein S11; Validated.	3.09243e-83
NC_021658.1|WP_044986939.1|12820983_12822687_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.92244e-99
NC_021658.1|WP_020740966.1|12840749_12841001_-|translation-initiation-factor-IF-1	gnl|CDD|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.23235e-41
NC_021658.1|WP_020740969.1|12843022_12843514_-|50S-ribosomal-protein-L15	gnl|CDD|235523	PRK05592, rplO, 50S ribosomal protein L15; Reviewed.	2.97166e-64
NC_021658.1|WP_012240549.1|12840601_12840718_-|50S-ribosomal-protein-L36	gnl|CDD|179039	PRK00465, rpmJ, 50S ribosomal protein L36; Reviewed.	5.34238e-12
NC_021658.1|WP_044986941.1|12832954_12834202_-|transcription-termination-factor-Rho	gnl|CDD|236490	PRK09376, rho, transcription termination factor Rho; Provisional.	0
NC_021658.1|WP_020740968.1|12841649_12842978_-|preprotein-translocase-subunit-SecY	gnl|CDD|236412	PRK09204, secY, preprotein translocase subunit SecY; Reviewed.	0
NC_021658.1|WP_020740967.1|12840997_12841639_-|adenylate-kinase	gnl|CDD|234711	PRK00279, adk, adenylate kinase; Reviewed.	1.9382e-95
NC_021658.1|WP_020740957.1|12827924_12829604_-|sensor-histidine-kinase	gnl|CDD|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	2.6814e-56
NC_021658.1|WP_020740963.1|12839105_12839735_-|30S-ribosomal-protein-S4	gnl|CDD|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	1.86082e-108
NC_021658.1|WP_063752086.1|12830735_12832838_-|GAF-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.14776e-44
NC_021658.1|WP_020740962.1|12837856_12838897_-|DNA-directed-RNA-polymerase-subunit-alpha	gnl|CDD|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	0
NC_021658.1|WP_044989545.1|12820496_12820790_+|glutaredoxin-3	gnl|CDD|239510	cd03418, GRX_GRXb_1_3_like, Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide reductase. It contains a redox active CXXC motif in a TRX fold and uses a similar dithiol mechanism employed by TRXs for intramolecular disulfide bond reduction of protein substrates. Unlike TRX, GRX has preference for mixed GSH disulfide substrates, in which it uses a monothiol mechanism where only the N-terminal cysteine is required. The flow of reducing equivalents in the GRX system goes from NADPH -> GSH reductase -> GSH -> GRX -> protein substrates. By altering the redox state of target proteins, GRX is involved in many cellular functions including DNA synthesis, signal transduction and the defense against oxidative stress. Different classes are known including E. coli GRX1 and GRX3, which are members of this subfamily.	4.4069e-34
NC_021658.1|WP_020740958.1|12829600_12830686_-|(Fe-S)-binding-protein	gnl|CDD|223325	COG0247, GlpC, Fe-S oxidoreductase [Energy production and conversion].	8.71656e-32
NC_021658.1|WP_012240542.1|12834589_12834868_+|acylphosphatase	gnl|CDD|224174	COG1254, AcyP, Acylphosphatases [Energy production and conversion].	1.35358e-34
NC_021658.1|WP_049949800.1|12837317_12837836_-|50S-ribosomal-protein-L17	gnl|CDD|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	8.15681e-46
NC_021658.1|WP_020740956.1|12824092_12826060_+|acetate--CoA-ligase	gnl|CDD|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0

Protein sequences

>NC_021658.1|WP_012240542.1|12834589_12834868_+|acylphosphatase
MGLKQVQLFVRGRVQGVFFRASTQREAKRLGLTGWVKNRSDGSVEVLAEGEEDELKELIAWANRGPSAARVERVDVRWRGFSGDFFDFRITD
>NC_021658.1|WP_044986941.1|12832954_12834202_-|transcription-termination-factor-Rho
MHLRELKQKPMAELVQMAKGLNIEGAAGLRKQEVIFALLQAHAAQDQPVYGEGVLECLPDGFGFLRAPDYNYLPGPDDIYVSPSQIRRFNLRTGDSVSGSIRPPKEREAYFALLKVDKINGEPPEVARDKILFDNLTPLYPQQKFNIENGTKSFSTRIIDMLCPIGKGQRCLIVSPPRAGKTVLLQQIANAISSNHPDTTLIVLLIDERPEEVTDMQRTVKGEVISSTFDEPPTRHVQVAEMVIEKAKRLVEHKHDVVILLDSITRLARAYNTVVPPSGKILSGGVDSNALHKPKRFFGAARNVEEGGSLTIVATALVDTGSRMDEVIFEEFKGTGNSEIHLDRKLMEKRIFPCLDINKSATRKEELLLPEWILQRVWLLRQLLHPLNVIDSMEFLLDKVSRTETNQEFLESMNQ
>NC_021658.1|WP_063752086.1|12830735_12832838_-|GAF-domain-containing-protein
MTAKAEQRTKALQARIQELEARLAQADKTVQALRDVGLALGSTLDLDQLLALILNKITELLDADRATLYLLDEQRQRLYSRIVIGEEARAIELPVGAGIAGHVAKIGRTIRVKDAYRDRRFQRDWDEVTGYRTRSILAAPMKNHVGRTIGVIQVLNKHGGAEFSVHDEELLSALATQAAVSIDNSRLFLSVIQKNTQLVETKEQLEHRVSDLKLLFELESAMGRATNMEDLARAVITSAGRACDARAGGMLVDEIEGGLVLYFFELDALEGGTSPPRAPAPDEEPEGVVVAAPPRPAVKRIAMRRGDGLVGRAMVHNEAVFYSSEGGGDELDDMDMTVSHRLAQMLGGELESAIAVPLEGEDAVPIGAMALYNSSKPHGFSKDDRALLRLVSANASTALRLFRSRLEREQSERLTTIGRLLSGVMHDVRTPLTVISGYVQLMASAPDAATREEHARLILKQFDVISAMQREVLEFARGERSILVRKVYLTKFFGDIEKQLEHELAGTGVALSLELEDRGTARFDEAKMTRLLHNLVRNAVEAMRPRGGTVTIRAYRDGGELAISVADTGKGIPKEVQGRLFQSFVTSGKRGGTGLGLAIVKKIVDEHAGTIAVESSDKGAKFTIRLPQGSASRPPAAVEGQPRLPPADGGPAPKAGGPAPKAGVEPSPVVHEGVPRRRPTGSSTPVNERGRRSSSNGSDA
>NC_021658.1|WP_020740958.1|12829600_12830686_-|(Fe-S)-binding-protein
MSQLRLKLLEQHRTSLEKCVYCPKLSRAACPVSNVEANETVTPWGKMSMAYFAARGDVPLDAPHADPAWACSACYACRERCDHKNEVATVLTDARAELFARGLEPEGARRVAARFRAREDGRAGERDGRAQPDPAAVHVLVGCGYERHAPDVARDALEATEALTGAPVRPVRACCGLPLLYAGDRPGFEAAARRLAAEVEAGERFVAVDPGCARAVRVEYARAGVSVKSPELFVDLAQASLDRLQRSTSERRVRYHDPCQLGRGLDRYDAPREILARITGRPPEEFIHRREHADCSGGGGLVPATRPASSAAIADGRIAEHRALGGGLLVTHCAQSLRRFRTRGEPAEDLASLVARAVAPR
>NC_021658.1|WP_020740957.1|12827924_12829604_-|sensor-histidine-kinase
MIAPAPAVDEARGGAAGQEGPARHKRRTVAGRLLASYLVVLAAFALTVGWSVQALRAASRDAQLLRAGYVPLLLRIGEVLAEQNVFNAQLNHITAAKNPGDVREWLETARRTRPLAFSIVKDAARALAGADEVEGGAGAGVGQAAGSSGVRRFSDEIAAEVTAIERIVGASPERFSQLFQALAVGNRELAERTRDELVKREVEGAQRLRAIKSRVEEQMESLTVEARRREERSMHLLLGLGVLTLLVGAVMSLYARRVLAPLTAVTERANAVARGDLTPKQVLATNDEIGELATTFEGMVAAIRRARAELVNAERLAAIGKMAAHVTHEIRNPLSSIGLNLELLEEEVARASAADMPDAELRPVMKESAQLVAAIRAEVDRLSRIAEQYLSVARRPRPQLVPERVDDLVQELVAFVRPELDRAGVAVRVEVEEGPEILLDESQLRQALLNLLRNAREAMPKGGEIVVSVRFSGGAATIAVDDTGPGVPEELRASIFDPFFTTKQRGTGLGLAVTRDIVEAHGGAISCEPREAGGTRFRIVLPAGGAPAQGRAAEAHAAL
>NC_021658.1|WP_049949799.1|12826312_12827866_+|serine/threonine-protein-kinase
MELEAGTVVANRYRIIRQLGRGGMGEVFAAENIRTGRQVAIKLLRADSKAKSSAVERFRREARAAGSINSDHVTEILDVEEDPELGIVLVFELLEGESLIDRLKRTGPIAFEELHPIIEQVWMGLADAHRAGIIHRDLKPSNVYLEARPDGSTRVKILDFGISKLPKEMGGETLTEMGQSLGTFSFMPPEQIGKAKTVDHRADIYACATMIYQSMSGQLPYQARNLLIMVEMKQKTDARKLADAMDGPVDPRLEAFLAKGLAREPADRFQSALEGLTAWRELRPAQSSSQPAVNPRSSRTPGSGASGHAPGTPLPSPHPTYKPPSSGALKLPVPPADPILIRTATDPGAHPPVEAPARKPSDPALAAHHFLGDPAPAPGEGQRPSHAAGGLPAVQPMHQPMPWTGPNGTMVLSNAAMELAPLAASPPVSPRTLPDFSEDSSPGPTSQGPTLVYRPTRPTLGSVGSGLPVPGEPGPLEPPPRAPPARTLRTLFYVLAALVFAVVGFLAMGLILEHLPK
>NC_021658.1|WP_020740956.1|12824092_12826060_+|acetate--CoA-ligase
MSQDAITSLLKETRRFEPPAEFSRRARVGAQEAYEALYRESIEQPDAFWRREAGDLVFRTPWTTTSDWSLPHAKWFLGATLNVTESCLDRHLTTATKNKAAIIWEGEHGATRTLTYAQLHRETLLLANALKKLGIEKGDRVAIYMGMVPEVAVAMLACARLGAVHTVVFGGFAADALRDRIHDSQAKLVITQDGAYRRGQVVPLKATVDKALAQPEAKSATRVIVYQHLGGERCEVQMTEGRDVFWHDLLAQAAPSCEPTIVDAEHPLFILYTSGSTGKPKGVLHTTAGYLVGVHVTTKYVFDLRDDDVYWCTADVGWVTGHSYIVYGPLSSGATCLMYEGAPNFPDWGRFWRLIEKHGVTILYTAPTAIRAFMRQGDEWPAKSDLSSLRLLGSVGEPINPEAWIWYHRTIGGGRCPVVDTWWQTETGAIMMTTLPGASHSKPGSTGLPMFGVVPEVVTKDGKPVPAGEGGLLVLKNPWPSMLRTVWGDDERFRKQYFSDVEGCYFTGDGARRDEDGYYWVVGRIDDVLNVAGHRIGTAEIESALVSHPAVAEAAAVGRPDELKGQALVVFVSLRPGFAAGPELQAKLAEHVAKEIGKFARPDAIRFADALPKTRSGKIMRRLLKDVAAGREMTGDTSTLEDLSVVAKLRQQEDE
>NC_021658.1|WP_148315046.1|12822802_12823927_+|hypothetical-protein
MENGIKLFQDRNYPAAIVEFEAAYGAKPKASPLFNIALAEKALFNYPRAIAALERALAQHRDTMDEGDERTARSAIEEMRALLAHLTIELSPPDARLLIDGEEQPPASSGTRVVELGPGVHRIGARAEGHVNAEQSVTVVSGERDKRVKLTLAPEKPPASATPQPYTPPPPPPPPRPVPLSLAPQGYYVIGAASLLWPLGHPRAFQLPEANSGGAGSIRVGYRVNTPAAFDVMFQYANIATGSDHPSYPNASYTLGSTRVGLNVRLMTPGQTWRFVGSIGGGLTYDDVSFDSIKGPGGDICDGRCKHAWGVNAFVFSEVGVELDLSGVLLGFSLDSYFQSSRGISYKDGDDDIPLYSSVLLQLGGSLHAGYAFW
>NC_021658.1|WP_044986939.1|12820983_12822687_+|serine/threonine-protein-kinase
MPSSTDTTAAATQPVEGALVGKRVQKYEIVRTIGRGGMGTVYEAVNTAIGKRVAMKFVDAELARNKDAVARFHREAQAASAVESAHIVEIFDAGFADDVPFLVMELLRGEDLGHRIRRCGRLELGEALHVTAQILRGLHRAHEAGIVHRDLKPDNIFLVDRDDDRNFAKILDFGISKVRRTDGVPAHTLTRQGTVLGTPFYMSPEQAQALPDVDGRTDLWAVGAILYECLTGHPPHSGSSYEQVIVNICMKDAQDVRMSNPAVPEPIARVIARALTRDRDARFSSARDFLDALVAGAGGLLGARRSSSDELGAHTTSAPGAPGQTPVKLTPGDPNIAMDPTLEVPGTGSKVGWASNGRAGARGPRRLALAGAALVALAGGLAGAAFHARRSPAESAEAAAPAPPAQVSVELRTNAEGARFTVDGVALADRTLRGRTGETKRVRIEASGYTTVDKEVTLQAGRAPIEVLLHPLPAAVAPAPAAEPAPTAALAPTAEPAPTAAPAPKAAPPPAPKAAPSAKKTATLPFAARPRATGAGAKAAAPGPVVAPDVATSKPAGVAAGLQLKVD
>NC_021658.1|WP_044989545.1|12820496_12820790_+|glutaredoxin-3
MQAADVTIYVTEYCGYCTMAKRLLSQKQVQFTQINVEGRDDLRAWLVKASGQRTVPQIFINGVSIGGFSELSALEKQGQLDPRLAEAPSPDAAALPR
>NC_021658.1|WP_049949800.1|12837317_12837836_-|50S-ribosomal-protein-L17
MRHKKAGRQFGRDTSSRRAMLRNLTANLITHERIETTDAKAKELRRVAERLITKATRLGKVAYTAHAELSPGDRARRLHAERLVGSYIPRWGVATDGKKVDIIAKVMIDLSKRFEGRPGGYTRIIKLGPRRGDNAPMSLIEFIDAPAVADAPAQAAEPVAAAEPATPATTAG
>NC_021658.1|WP_020740962.1|12837856_12838897_-|DNA-directed-RNA-polymerase-subunit-alpha
MTMNNPNLTMIARNWRDLIRPKGISIDAESGTQFYAKFTCEPLERGFGITIGNSLRRVLLSSLQGAAATAIRIEGALHEFTTVPDVVEDVSDIILNVKEVVFKAATPKTYSVRIDREGPGPVYARDIQLVDGLSVLNPDHLIAVLDKKGPLSMELTVNVGRGYVPAERNKTPTMPIGTIPIDALFSPIRKVNYTVQNARVGQVTDYDKLTLEVWTNGSVSPADAVAFAAKILKEQLSIWVNFEESEETSYQAVMSDDEPLNENLFRSVEELELSVRSANCLQNANITLIGELVQRTEQDMLKTKNFGRKSLKEIKEILANMGLSLGMKIDNWPQLLERWKAQQAQA
>NC_021658.1|WP_020740963.1|12839105_12839735_-|30S-ribosomal-protein-S4
MARYIGPVCKLCRREGMKLYLKGERCYSEKCAYTRRPYPPGQHGQGRIKLSEYAVRLREKQKVRRIYGVLERQFSGYFQEANRRKGRTGEEMLALLERRLDNVVHRMGFGSSRAEARQLVRHGHVHVNGKRLDIPSYVVRAGDRIELTEGARKFKSVLASVGGADKRPVASWIDVDRAAFTGAIKGAPIREDLNEPEIREQLVVEYYSR
>NC_021658.1|WP_020740964.1|12839746_12840157_-|30S-ribosomal-protein-S11
MAQAKTAATTTKAKQKKKVKKNVAAGIAHIQSTFNNTVVTITDINGNAIAWSSAGARGFKGSRKSTPFAAQLAAEEAARRAQEHGMRSVAVFVKGPGAGRESALRALQTAGFKVTLIRDVTPIPHNGCRPPKRRRV
>NC_021658.1|WP_020740965.1|12840177_12840558_-|30S-ribosomal-protein-S13
MARIAGVDLPRRKHVAFALPYLYGIGRTLALQICEKTNIAPNRRVEELSDAEVKAIRDLLDAEYKVEGDLRREVQLNIKRLMDLGCYRGLRHRRGLPANGQRTHTNARTRKGPRKGMLQRRPAATK
>NC_021658.1|WP_012240549.1|12840601_12840718_-|50S-ribosomal-protein-L36
MKVRPSVKKICDKCKVVRRRGVVRIICENPRHKQRQGN
>NC_021658.1|WP_020740966.1|12840749_12841001_-|translation-initiation-factor-IF-1
MRRSKQARPPKEPKGDKLEFDGVVQEALPNAMFRVKADNGLGVLATISGRMRQYYIKILPGDRVTVEVSPYDPSRGRITYRHK
>NC_021658.1|WP_020740967.1|12840997_12841639_-|adenylate-kinase
MILVLVGPPGAGKGTQAKLLCSRFGIPQISTGDMLREAKRAGTLEKRYLDIMDSGGLLPDEAVIGLIARRTVEPDCGNGFLLDGFPRTVPQATALDELLASQGGRRIDAVLQLDVPRPLLEERLIHRRTDKRSGQIYHLVYNPPPPGAELEHRADDRPEAVSKRLDAYDAMTAALLPFYEEKQLLHRVDGVGKPEEVTHRVLSAVGRSGSGGE
>NC_021658.1|WP_020740968.1|12841649_12842978_-|preprotein-translocase-subunit-SecY
MASLAGITNFHKIPELRRRVIFTLVMLAVYRVGVFVTTPGVDRNAMRQYVAKQSGGLIGFFNMFSGGALENLSIFALGIMPYISASIIMQLMGMVYKPIDELRKEGEQGRRRLDQYTRYGTVALSLFQAFSIAKMLEGLSSSETGAGIVNHPGIGFQLMTVITLTTGTAFLMWIGEQITERGVSNGVSLLIFASIITSIPGEIGNYFAQNAGDLQPLTMAAIVAFIVFVIGVIAFFENGRRQIPIVYSRRQVGRRVYGGQTAHLPLKVNTAGTIPPIFASSLLMFPQTLANMNVPGADTLQAIINRGDWVFNTGYALLIIFFCFFYTNVTFQPVDVAENLKKQQANIPGIRPGKQTADYIHRVIQRITVGGALYVAAVCVVPSIVGNLLRVPFGFGGTSLMIVVGVALDTVNQLEAHLITRSYEGLTGPGATRIRGRRLPEA
>NC_021658.1|WP_020740969.1|12843022_12843514_-|50S-ribosomal-protein-L15
MDILSKLQAPEGAVTKRLRVGRGVGSGVGKTSGRGQKGQKARAGGNINKKHFQGGQTPIQRRLPKRGFRNPLADIVANVNVGALEAFDDGAQVDVAALQASRLVQGRFDVLKILGSGELTKKLTVTAHRFSKGAVEKIEKAGGKVVVLASPASQDNSTDSSSS

Crispr_ID: NC_021658_59

• CRISPR_ID: NC_021658_59
• CRISPR_location: 12863887-12863963
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_59

Consensus_repeat	Method
GATCGCGCCCGCCGGCGCCGTGAGG	CRISPRCasFinder

spacers of NC_021658_59

>59.1|12863912|27|NC_021658|CRISPRCasFinder
CCCCGGCGCGATCGCAGCGATCGCCAC

CRISPR arrays and Neighbor proteins around NC_021658_59

CRISPR arrays

The CRISPR arrays of NC_021658_59

>merge|NC_021658|59|12863887-12863963|CRISPRCasFinder
GATCGCGCCCGCCGGCGCCGTGAGGCCCCGGCGCGATCGCAGCGATCGCCACGATCGCGCCCGCCGGCGCGGTGAGG

>NC_021658|59|52|12863887-12863963|CRISPRCasFinder
GATCGCGCCCGCCGGCGCCGTGAGG	CCCCGGCGCGATCGCAGCGATCGCCAC
GATCGCGCCCGCCGGCGCGGTGAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020740996.1|12870722_12871616_+|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|225088
NC_021658.1|WP_020740990.1|12863636_12863819_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_012240567.1|12849200_12849539_-|50S-ribosomal-protein-L22	unknown	unknown	gnl|CDD|234793
NC_021658.1|WP_063752089.1|12869845_12870676_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|225438
NC_021658.1|WP_148314458.1|12862997_12863294_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020740997.1|12871612_12872614_+|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl|CDD|227278
NC_021658.1|WP_187345784.1|12868618_12868798_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314457.1|12859351_12861058_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_021658.1|WP_020740991.1|12864018_12864519_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044989552.1|12868892_12869825_-|hypothetical-protein	unknown	unknown	gnl|CDD|223301
NC_021658.1|WP_044986947.1|12850197_12850932_+|hypothetical-protein	unknown	unknown	gnl|CDD|240291
NC_021658.1|WP_187345783.1|12867659_12868334_-|hypothetical-protein	unknown	unknown	gnl|CDD|236138
NC_021658.1|WP_020740999.1|12873475_12874099_+|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	unknown	unknown	gnl|CDD|234648
NC_021658.1|WP_044986949.1|12852379_12853804_+|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NC_021658.1|WP_020740985.1|12855908_12856574_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|225136
NC_021658.1|WP_020740988.1|12861236_12862517_+|hypothetical-protein	unknown	unknown	gnl|CDD|223839
NC_021658.1|WP_020740992.1|12864578_12867635_-|PD40-domain-containing-protein	unknown	unknown	gnl|CDD|223893
NC_021658.1|WP_020740998.1|12872705_12873479_+|ribonuclease-PH	unknown	unknown	gnl|CDD|178914
NC_021658.1|WP_148315047.1|12851253_12852150_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|335469
NC_021658.1|WP_020740983.1|12853896_12854421_-|hypothetical-protein	unknown	unknown	gnl|CDD|215641

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_012240567.1|12849200_12849539_-|50S-ribosomal-protein-L22	gnl|CDD|234793	PRK00565, rplV, 50S ribosomal protein L22; Reviewed.	2.19896e-41
NC_021658.1|WP_063752089.1|12869845_12870676_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|225438	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning].	1.14383e-98
NC_021658.1|WP_020740997.1|12871612_12872614_+|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl|CDD|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	1.1921e-27
NC_021658.1|WP_020740988.1|12861236_12862517_+|hypothetical-protein	gnl|CDD|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	1.69648e-39
NC_021658.1|WP_187345783.1|12867659_12868334_-|hypothetical-protein	gnl|CDD|236138	PRK07994, PRK07994, DNA polymerase III subunits gamma and tau; Validated.	4.34713e-12
NC_021658.1|WP_020740996.1|12870722_12871616_+|FtsX-like-permease-family-protein	gnl|CDD|225088	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning].	3.27867e-38
NC_021658.1|WP_020740985.1|12855908_12856574_+|methyltransferase-domain-containing-protein	gnl|CDD|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	1.33822e-26
NC_021658.1|WP_044986947.1|12850197_12850932_+|hypothetical-protein	gnl|CDD|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	2.39692e-06
NC_021658.1|WP_148314457.1|12859351_12861058_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	3.21683e-12
NC_021658.1|WP_020740999.1|12873475_12874099_+|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	gnl|CDD|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	2.68705e-91
NC_021658.1|WP_044989552.1|12868892_12869825_-|hypothetical-protein	gnl|CDD|223301	COG0223, Fmt, Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis].	6.79686e-55
NC_021658.1|WP_044986949.1|12852379_12853804_+|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.000367165
NC_021658.1|WP_020740992.1|12864578_12867635_-|PD40-domain-containing-protein	gnl|CDD|223893	COG0823, TolB, Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion].	5.92448e-25
NC_021658.1|WP_020740998.1|12872705_12873479_+|ribonuclease-PH	gnl|CDD|178914	PRK00173, rph, ribonuclease PH; Reviewed.	1.10875e-117
NC_021658.1|WP_148315047.1|12851253_12852150_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	0.000295681
NC_021658.1|WP_020740983.1|12853896_12854421_-|hypothetical-protein	gnl|CDD|215641	PLN03237, PLN03237, DNA topoisomerase 2; Provisional.	2.91711e-05

Protein sequences

>NC_021658.1|WP_020740990.1|12863636_12863819_+|hypothetical-protein
MGKRDRRQSMKMRRRKAQAAKKERAKRSKLSRATTEVAGKAKKPRAPKSAAAPATPAPAS
>NC_021658.1|WP_148314458.1|12862997_12863294_+|hypothetical-protein
MQLVLGRDLRASISVVQVVLRKLGRGSRAVVGRLVRAPRKGSVIVIEFSDGMHEYVTTPVKRVLRLAGREVFYIETVNSRYRLEVRGREVALDGAVGG
>NC_021658.1|WP_020740988.1|12861236_12862517_+|hypothetical-protein
MREMRQWIAVGAAVGLVAVTLPMLREHDVQLGGLLAKKTTAGGPKITRTVTPPPLTDLDLTRIDDRRSPPTAPAHGGRVAELTIDPMYQRAAIGFLRAGRVPEGAVVMTDIRTGKVLVWASYVHEGALHDVAAEATAPSASVFKIVTGTALVEAGLSPNTKQCYSGGEHSIRPADMIDNKRRDKYCATLTQAMGRSINTVFARLAAKNLDHEKLGAVAAKLGWGQDTPFDVNVATSTIALPEDELGFARTAAGFWNTTLSPFQAANLATTVANGGEMIRLHVVSSVKDEIGEIYQGVSERQVLKRVMDESTASAVTTMMEATVDNGTSYRSFHDRNGRAYLPDIRVAGKTGTLTKPRPEGPFYTWFVGFAPSRKPEVAISVMVANGAKWRVKATNVACDMLRTYFADKGAPGVTDPNNRTGSTARR
>NC_021658.1|WP_148314457.1|12859351_12861058_+|hypothetical-protein
MGPGAVPPAGAVPPAGAVPPAGAVPPAGAAAPAPPPAAAPAPPPEPVPRARRGRPPPPPPGAPAAAAPPPPPPPPEVFAPTAEAAIVKEQQPLAGWHGGFFLRDASDTFRLYPKARLHLDFISSFGSGVSDVEASDGGNALQPRFFARRARLEFDGEFLKRWSFKLDVDFGGQSLGNANGKTESSAAAAGDTPTAETARFAAVQSASVGASLADVWINYSVMPALNFMLGQFNSPFGMEIQSSSNAITFMERNIAMRSFAHPEGKSIGLMAWGDVADKMFFYGIGVVAGDGQNRPGVDAPPDLIGRVFARPFLADKKGLLAKAQIGISAMHGERDQAYVGYDYASIRTGNGYTLWGGGYRDSLGRQIHVIPSGAQNAIGAELRLPIKMVELRAEAVYLANNTREAVEGYQLTNTERLGQVRGLGWYVQLSAWPVGDAFVTGDPGYSPRPAKVDLTKEAEKPKSGLEVAAILAGINATYDGASRENGGVYDANTPGAEGGPGTDLQVMQVGLGANYWHTKNVRLSVNYNAYLTPGSGSDENLLRVPGNTLKRADAHALHELGARVGLSF
>NC_021658.1|WP_020740985.1|12855908_12856574_+|methyltransferase-domain-containing-protein
MSLARVLEPEVMDTDEDARAYDSMDHAAVNTAFCDALLCHDPDLAYALDVGTGTCLLPIELCRRVPTARIKAIDLSASMLDLGRRRVEQAGLTGAIALALADAKALPEPDETFSAVLSNSIVHHIPEPMQVMREMFRVLRPGGLLFIRDLLRPEDEASVAALVATVAANDTPYQRALFDASLRAALALEEVREILRSLGIPPECAQVTSDRHWTVAFRRAS
>NC_021658.1|WP_020740983.1|12853896_12854421_-|hypothetical-protein
MPDEAILALVKNQLGAVTGEAPLVPPPAPRRSRTRARAGAVQSKPSSVAAKRGAAPKRRPGRPRKSPAASAERQETLDAVERVVKASSGVSASEVAKQAGIPQTRAAAALKELKLEKRIFQGGDRRFARYAGDAKTAEQASANARKTAAGPAPAAKKPAAKGRKRVAQAAAPAK
>NC_021658.1|WP_044986949.1|12852379_12853804_+|hypothetical-protein
MLDSGVSAAARRRAVATALAALTALLALGCRKKEKPEPITVPPPGAASQDELTTAIGQARGIASALAPSSTRWRRVFVLDDKRAVVTGEVENEAVALVTETAGRTWRSLRRLREGWSTWSVGADGATVLTAGPRGPAPAKDARGARGAPPAVDPPSLFFAPFEASELSAPSSVALPELGRGARPLANSISAVLSAESAALLVEPRPRRAALVYGGPPGAAPVPPVQLPAQEQALPVPYGRPPAILSVRGRNLLARPVPEPGKPLDAPRIIEGLAMSPAATVALSAPPACDFAGWSIQVVPQPPDKAAVLAVSATQTAVLKLPAKAAPDAVVGCAADRIMVEVIAPTTGERTLATCTLEGACVLAEKPPFRPWLEPHERSIALAPTRQGVAAVLTSRTATRWGLYIAQSPEAGKIYDVPRVIGEDSGERGRIELGALLSFGNRLLMLLQADVTGTSRRGWYVMASEDSGLTWSPP
>NC_021658.1|WP_148315047.1|12851253_12852150_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MVVASAGCAPGSTTAEQITPRVVARASFEGAAAIVVDRPLKAKESALSTVKDSAVIASVMEPETSAAAVSSSTSSARCPAEMALVEDRVCVDRWEGTLVELTPGGERPWSPFDPIDGNERRVRAVSWPGVIPQGYISGLQAKRACAASGKRLCTSDEWVSACRGPEETLFPYGASRQHGVCNDDERPVHPVAEIAALLGIKSEEHWTSAMNNPLINQLSNALLPTGERAGCTNGYGVFDMVGNLHEWVDDPSGTFRGGYFMDTTRNGEGCKYATTAHSFGYHDYSTGFRCCMDPEQAD
>NC_021658.1|WP_044986947.1|12850197_12850932_+|hypothetical-protein
MLARHRHSFFALTLILPAVVGGCVVTSADTDNDPDQTTGPGVTHSSSTGGGDGGEGGQGGDGGEGGQGGDGGEGGQGGEGGEGGGGACVEAGSSTVTVAACERLNIAPAQGATSQCGEGRDEEPIGYRLCKRAFTLFAPSHAADLVDCLGDIGVQYACDIEPAQECLTEMYENACPNQALSTCNEIADDCDESFNPGQCAADLNPFTNAGVDELIECMNDGFEADENLTCRAAYTDCYQTVMSF
>NC_021658.1|WP_012240567.1|12849200_12849539_-|50S-ribosomal-protein-L22
MVSKASAMFSRIAPRKARMIADLVRGRDADEAIQLLSFTQKSGAPVLRKIIESAVANAQQAGADIDALFISKATVDKGPNKFNRRWRPRAMGRATRITKGVSHIVIEVDERK
>NC_021658.1|WP_020740991.1|12864018_12864519_-|hypothetical-protein
MRALLALSLALAGCGIAPSNSQRLTEAALEMNTAARFGRMDVALERVGSRAREDFMRRHADWGARLRVVDVEFGGFEMTQRDEAEVYLEVLWLRHDEATVRTTRIAQRWRDERGHWELVGEERRDGDTGLLGEPPPKEKPAGEAASAIDPGRRPGLSLHTRVIRDE
>NC_021658.1|WP_020740992.1|12864578_12867635_-|PD40-domain-containing-protein
MNRFFSRSGSRASRPLRRAASVLSAVALAALLLLAPRPARATGDPDLAFWTYETDHFRVHHPQGLEPIAARIAVLAETIYGRVEGALGYAPRDRTEIVITDDSEIANGSAGTLPYNAIHLLASGPEDMSTLGDYDDWYLDLLTHEFTHIAHIDNTSGIPAILNAIVGKSFSPNQVQPRWIIEGLAVVSESNHTSGGRMRSTMFDMYLRADVLEDNIAGLDQISSSPFRWPQGTLWYLYGSRFLGWILDVYGPNTMRAVSADYGASLVPWGINRAIRRVTGKTYVELYEGWKDHLRRLYREQMAAVEARGLREGARLTHHGRTVHYPRFVPPVARRTSADEVVYFRDDGRERPGIYRLSLAAPAPGPGTERKETLVARTNTASRPAFTPAGDMIFAALMPWRNQYYRDDLVFLPRGEEAPDGDEPSRRRLTRGLRSSAPDVSPTGDLVAFSLNSKGTRYLEIARLSRDGALSERRDLVPSARFEQAYSPSFSPDGKRLAYSAWTAGGYRDIRVVDVATGSFREVTRDRATDMSPVWSPDGETLYFTSDRTGIHNVYAYALSTGALRQVTNVRLGAFHPAISPDGKTLVYVGYTSRGHDLFVMPLDPARFLPAPPPPTDRPDPPTAPAAVRLERSPYNPLPTLAPRAITLDYAPGSYGSNALTVSVTGSDIVGRHSVFGELTVQPDAPAPTVLVGYTYGRLPIDLGVRAYYAMTPRSGYRINGRNVTYDERSIGVVSGVSYPIRGEFSRQSLAASFSSVAFKGQLPIGSELDPYAPRTILPPQGTLNLAHIGYGFSNAEGSIEASGAPRGISLNAGLDYAGPETGSSYTTYAFSTSLSAYVAMPWPGDHTLAFRVAGAVSGGNFPRGAAYAVGGYDLENLTLVDTLLTGVTNSSFTLRGYAPGVMAGRSYFSQTFEYRVPVVEPDRGLSTLPLYLRRVDASLFLDHGGAFNRFETDDLALFTQGSLLYSPQLHTSIGGEVWLSLTLGYVLSSQLRFGYALGLSPLAIPGGQLYFVATNSF
>NC_021658.1|WP_187345783.1|12867659_12868334_-|hypothetical-protein
MAPAPVAVAPAPVAVAPAPVAVAPAPVPPVAAPAPVAAARAPAPVAAPAPVAEAAPAPVAVAAPPHLQHTLPSPQPPRHAPAPPAYPAAPHPAADARRAPPPQAAQPPVDNRAPAAIVDVELGALTPSNFYKGLAGNDVIEHGGIFVATYKIPPIGSVVTLRVRLPGDYEFTALAAVRWTREAGGSKDSAEPGFGARITQISAEGRQLVSRFTRNREPLFYDDL
>NC_021658.1|WP_187345784.1|12868618_12868798_+|hypothetical-protein
MMPIACAIGSASASTSGDTRPFDWSALSADASSSRALFASCAGSDMNPPKGASYAVARA
>NC_021658.1|WP_044989552.1|12868892_12869825_-|hypothetical-protein
MFGHGKLFGRRPGERPLRVAFFGLPLAALLLHGDGHEIALAAISRADAVGLRRARRLFGERLLLRPDVERPELRSRVEALAPDLLVSWFWTTRLPMSLVRAARLGGIGVHPSLLPRHRGPDPTYWAIASGDAESGVTAHRIEAEYDTGDILDQERLPIDPAWTAWQLARALDRPSLRVLRRTVARFARGDEVAGVAQDPALATQAPAPDDEACAICWSWPTERVLRHIRALAPAPGAWTEIEGACVIVLRAAPAPTFPGALAPGEAVAQGGVVLVRTGDTAVALLEAEIDGEPASAGELAALVASGAPSG
>NC_021658.1|WP_063752089.1|12869845_12870676_+|ATP-binding-cassette-domain-containing-protein
MAAPPPQGSFRPALRPGHRYDASAARRPILVFEDVYKSYRADQPVLRGMSLSIERGEFVFITGPSGSGKSTLLRLVHRTERVDDGRILFLGRDIARLTDTSIPALRRNIGFVFQDFKLVPSWTVFDNVAIALEVLGLPSRLLRTRVGEALERVGLSGRGGDRAQVLSGGEQQRVSIARAIVGEPALILADEPTGNLDPQLAIDLLGLFEDIHETGTTVLFATHDRTLLDVRPRRVVVLDDGKATDVPHGLGSGGELAVDDGDAVEDEMDSGVRGAA
>NC_021658.1|WP_020740996.1|12870722_12871616_+|FtsX-like-permease-family-protein
MQTSERDDRRRWLRTWRAGRSDWRLQALSIFSLAVAFVCLASALLVVTNLMAVRDRWSRAGRATVYLRDSATDAEIAELTRALEGTDGVKKVRLVTSAEARREVVHDDGDKALAALPPSAFPASLEVGFTEEISDEALASMTVKLRALPAVDTVETYQRWTERLSSLLGGGVAASTCLAAIVLCAVVSVIGSTMRLLLHRRKIEVEVLKLVGATDGFVRRPFIVEGATQGAAGAAGALLMLGALFLMVRGRFDHELANLLGVSPSFLPWEVALGMVGLGAALGAATALLTLRKMVAV
>NC_021658.1|WP_020740997.1|12871612_12872614_+|peptidoglycan-DD-metalloendopeptidase-family-protein
MRRRARLAPIALALLTGAATSGAAVPAADAPSSASLAAPAARPSSALAENDLDRLLAKLDAEEKALRAELDAIGPALELTRRRMVARGRAYYRHVRAGFLPVGGGFDALVDHAARVERTRLALERDLAREAELTRRSAELADRLTHLGAERAPLEVHREAMNRARVALAQEEERRAAFARAFETSVRPDYLAIYGADTGPAELDRRAGFRSLLGRLPFPIAGRAEVRKVSRRGAGGPGVELTALSGAPVRSVAAGRVAFADTYADYGLTVIVDHGERHYSVYANLGAADVRAGDQVAGGARVGTVGSGPDGAKLYFELRRGAEVIDPGPWFGM
>NC_021658.1|WP_020740998.1|12872705_12873479_+|ribonuclease-PH
MNRPDGRALDVHRPVEMILGFHRNAEGSVLYRAGRTVVLCTASVEPTVPAWMIGKGAGWLTAEYQMHPRSSPTRREPRDGRGKAPSGRTQEIQRLIGRALRAAVDMKQLGEQTIAIDCDILEADGGTRTASITAGFVALALALDRMRAAGSLKGPALRDQVAAISVGHLPGGLALDLVYTEDSAARVDMNVVATAVGAIVEVQATAEDEAIPRTELDRMIDLALAGVASLASAQHRALSDAGVDLAALFQTDHWRVA
>NC_021658.1|WP_020740999.1|12873475_12874099_+|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase
MSREPLCLLAATSNRGKLAELRSLLADLPIEVRSLAEVLPDAPPVVEDGATFLENALLKVRAGALRSGLVTLAEDSGLEVDALGGRPGVRSARFAGEHATDAENNAALLAALADVPDDQRRARFRCVMVLLDPRSAEPPVVTEGRCEGWIGRQPKGSGGFGYDPLFVVEAYGRTMAELGEAEKNRVSHRGEAAQAMRSALEALIARR

Crispr_ID: NC_021658_60

• CRISPR_ID: NC_021658_60
• CRISPR_location: 12914976-12915078
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_60

Consensus_repeat	Method
CGTCGCAGAGCGGCGGTCACCCGCACAG	CRISPRCasFinder

spacers of NC_021658_60

>60.1|12915004|47|NC_021658|CRISPRCasFinder
TGAACGACTACGCGCTCGCGCGGAGCTGATCCGCGCCCTGCGTACGC

CRISPR arrays and Neighbor proteins around NC_021658_60

CRISPR arrays

The CRISPR arrays of NC_021658_60

>merge|NC_021658|60|12914976-12915078|CRISPRCasFinder
CGTCGCAGAGCGGCGGTCACCCGCACAGTGAACGACTACGCGCTCGCGCGGAGCTGATCCGCGCCCTGCGTACGCCGTCGCAGAGCGGCGGTCACCCGCACAG

>NC_021658|60|53|12914976-12915078|CRISPRCasFinder
CGTCGCAGAGCGGCGGTCACCCGCACAG	TGAACGACTACGCGCTCGCGCGGAGCTGATCCGCGCCCTGCGTACGC
CGTCGCAGAGCGGCGGTCACCCGCACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020741024.1|12905418_12906615_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NC_021658.1|WP_148314466.1|12903728_12905357_+|hypothetical-protein	unknown	unknown	gnl|CDD|237537
NC_021658.1|WP_020741034.1|12918876_12919881_+|hypothetical-protein	unknown	unknown	gnl|CDD|366586
NC_021658.1|WP_020741033.1|12917953_12918709_-|hydroxyacylglutathione-hydrolase	unknown	unknown	gnl|CDD|274569
NC_021658.1|WP_020741030.1|12913887_12914907_+|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NC_021658.1|WP_020741031.1|12915180_12916107_-|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl|CDD|223318
NC_021658.1|WP_148315049.1|12923026_12924112_-|3-methyl-2-oxobutanoate-dehydrogenase	unknown	unknown	gnl|CDD|213783
NC_021658.1|WP_044986960.1|12906972_12907308_+|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|143393
NC_021658.1|WP_020741027.1|12908960_12909308_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_063752173.1|12919985_12921140_+|bifunctional-methionine-sulfoxide-reductase-B/A-protein	unknown	unknown	gnl|CDD|235499
NC_021658.1|WP_020741028.1|12909304_12913204_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_021658.1|WP_020741036.1|12921456_12922863_-|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl|CDD|235798
NC_021658.1|WP_020741026.1|12907567_12908437_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020741039.1|12924708_12925323_-|DUF4149-domain-containing-protein	unknown	unknown	gnl|CDD|372664
NC_021658.1|WP_020741029.1|12913496_12913757_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_049949805.1|12901237_12902380_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|237865
NC_021658.1|WP_020741038.1|12924324_12924600_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020741022.1|12902712_12903699_+|PEGA-domain-containing-protein	unknown	unknown	gnl|CDD|285503
NC_021658.1|WP_020741032.1|12916103_12917888_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153255
NC_021658.1|WP_020741040.1|12925319_12926366_-|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|224331

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020741024.1|12905418_12906615_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	9.05238e-22
NC_021658.1|WP_148314466.1|12903728_12905357_+|hypothetical-protein	gnl|CDD|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	0.000746813
NC_021658.1|WP_020741034.1|12918876_12919881_+|hypothetical-protein	gnl|CDD|366586	pfam01351, RNase_HII, Ribonuclease HII.	0.00487696
NC_021658.1|WP_020741033.1|12917953_12918709_-|hydroxyacylglutathione-hydrolase	gnl|CDD|274569	TIGR03413, GSH_gloB, hydroxyacylglutathione hydrolase. Members of this protein family are hydroxyacylglutathione hydrolase, a detoxification enzyme known as glyoxalase II. It follows lactoylglutathione lyase, or glyoxalase I, and acts to remove the toxic metabolite methylglyoxal and related compounds. This protein belongs to the broader metallo-beta-lactamase family (pfam00753). [Cellular processes, Detoxification].	1.63634e-116
NC_021658.1|WP_020741030.1|12913887_12914907_+|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	8.73356e-25
NC_021658.1|WP_020741031.1|12915180_12916107_-|NAD(P)-binding-domain-containing-protein	gnl|CDD|223318	COG0240, GpsA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	3.86044e-48
NC_021658.1|WP_044986960.1|12906972_12907308_+|nucleotidyltransferase-domain-containing-protein	gnl|CDD|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	1.81393e-12
NC_021658.1|WP_063752173.1|12919985_12921140_+|bifunctional-methionine-sulfoxide-reductase-B/A-protein	gnl|CDD|235499	PRK05550, PRK05550, bifunctional methionine sulfoxide reductase B/A protein; Provisional.	4.24165e-159
NC_021658.1|WP_020741028.1|12909304_12913204_+|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	5.568e-19
NC_021658.1|WP_020741036.1|12921456_12922863_-|dihydrolipoyl-dehydrogenase	gnl|CDD|235798	PRK06416, PRK06416, dihydrolipoamide dehydrogenase; Reviewed.	0
NC_021658.1|WP_020741039.1|12924708_12925323_-|DUF4149-domain-containing-protein	gnl|CDD|372664	pfam13664, DUF4149, Domain of unknown function (DUF4149).	2.31933e-11
NC_021658.1|WP_148315049.1|12923026_12924112_-|3-methyl-2-oxobutanoate-dehydrogenase	gnl|CDD|213783	TIGR03181, PDH_E1_alph_x, pyruvate dehydrogenase E1 component, alpha subunit. Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase].	5.14925e-156
NC_021658.1|WP_049949805.1|12901237_12902380_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	2.33769e-09
NC_021658.1|WP_020741022.1|12902712_12903699_+|PEGA-domain-containing-protein	gnl|CDD|285503	pfam08308, PEGA, PEGA domain. This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteristic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	3.79411e-05
NC_021658.1|WP_020741032.1|12916103_12917888_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153255	cd07993, LPLAT_DHAPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.	3.85707e-31
NC_021658.1|WP_020741040.1|12925319_12926366_-|HEAT-repeat-domain-containing-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	2.998e-11

Protein sequences

>NC_021658.1|WP_020741030.1|12913887_12914907_+|ParA-family-protein
MKTIAFFNSKEGVGKTSLVYHLAWIYHELRKRVVAVDLDPQSNLTTEFLPAERLEQLWLDHDHPHTILGAIQPLLHHLGDLAPPHVEIVDDSPWRSLSLVPGDLGLGLFEDRLAEAWNKCLSDSPGEAADAFRVTSAFHRILERAAAQTEADLILLDLGSNLGAISRAALLAADFIVVPLGADLFSVQALRTLGPTLAAWRRAWEERLDNKARPEEISVPRGEMRPLGYVILQYAAREAYPARAHQRWIPKIPKAYRQVLLGEDGDAPSPAPHHLATLRYYRGLMPMAQEARKPMFLLTPADGAIGSNAAAVQNCRRDLEALARRIAAAAGIPLAPRPT
>NC_021658.1|WP_020741029.1|12913496_12913757_+|hypothetical-protein
MGDDQHRQDGGQQAEASPTPQHADEPSVDPVNRPDPIIELYKKHVDRSLLRENLKLTPEQRLLKMMDLQRFAAELQRAGRAARKRP
>NC_021658.1|WP_020741028.1|12909304_12913204_+|CHAT-domain-containing-protein
MSVLDLAIIVGAPPQGAGPEVLGTIVLTCDALGLSHAAAPLVDPLSEGERKELDWYLEEFWKWPFEGFAARGARIERALPEIGRRLFQSAFGSADAQRVFLQWHREPLEEGQRRQISLRTELPAALRLPWELLHDEQGYLVLRTRNPVSIVRRLPQAQLSDRSAKFEPPLRILLVTARPSGTGFIDPRNVARALLDALDPLAEAGSVEVEILRPPTLSALRTRLRDAKRPVHVLHFDGHGHFEPAAAAHGGPCMDGGTGTLAFEDEDGGHAPVAAPQLAQVLQNSGVPLVVLNACRSARGGDSDAFSSVAAALVRSGIDAVVAMSAKVLVVAAARYVEAFYGAIAEGEPVPAAHERGRQRLHDEPRRHVYRRRRDERGAPVALCDFWLPHFYQQRPLQLSPRAPASRRSPREAPRFTGLPEDPRYGFSGRGRELLDIERALLRGKIVLLHGFGGTGKTALAAEAARWLCRTGMYRGACFVSFEHGGDAARVLGRLAEHLGVSDGGFDADDATAALASLVPALVERPTLLVADNLESVLPGGDAALAAGERAALWQALVQLATVPKGGCGVILTSRDAALGDGRLAPGQRAMHREVRGMDPDDAHALAARLLGDLGIDPRRAPYPELRDLLQKLDHHPLAIQLVLRALGDTTLTLTAIDEEFVKLLPRFADDTETGRSRSLMASLEYSLLRLSPEQRGLLIRLAPFEGGASEDDLLAITEIPEAAWIKLRPALEQAALIRAEQVHEVWATPFLRFHPVLAPYLRMKAGAEDEALRERHAQRYTQLAGHLYRADNPYPVAARALARFEMPNLRRALHLRIAAGALDEATDMADSLARFLTIFGHRRELEQIRRQVEEAMERARPAPDGNFTRAEYLRQTGLAEDALHRGDIGAALQGFTALLQRIQALPEGTERGRGSYEHCLVLSWLGRCLTAGRKPAGAEARHRDALHAIEALIERDCERKDDVRLRAVVLTELGDALLQQGKYGEARSAYEASLEVSKALNDVRSQAVTLGQLGVLAMHEQDYPEAKQRHREAIVFFGNLQEPGAEAVAWHQLGHIFRWEMNWGEAERCLRQSLKLSEEAGDAGRTAATCTELGTVAYLAGHAEEAELWYRKALKTFQALKDATSQSVLLNNLAELIQHEARAGRYPTSRLAEARALAEQCLKIMRTLDASSELWKTLDILASIAEQDGDEETARRYRREARETFAAFAGNRYGIDKHFGGLIHALASAAAQPDLRPEIEPLLSKLEAADWRITTPVRRLWAGERDWHALAEGLDRDDALLMLRVLETLAGTAPPAEP
>NC_021658.1|WP_020741027.1|12908960_12909308_+|hypothetical-protein
MPRPFVITLPEPDDELHDAIARALGEDAEIHEHPPDYGLEDIKLIIEIAAGVSGVIVGIPEVVKVLGKLRDVLRSRAKQKRVRIKVLDGGADVVLTEVSDEELQKLAEESRKDRA
>NC_021658.1|WP_020741026.1|12907567_12908437_+|hypothetical-protein
MATARTKKKSAPAKPSAPDEAAEAFAQIEPELDRIEKVVPINVDIPRAVAVAVGAVPHLKALRARFVDELPRFPIEALDKLMSYALGAWYAHLLALPAGPGQEGLKRLLDEASALRADLLVAAEALAHKGFVDAGRVAEIRSGNGHLDTANDLVALAALFGESWGAVKHKTTVEWPEVERASKLGPELLVALGARNQPGVPAPKAADPADRRARAFTLLVRAYDQCRRGVTYLRWIEGDYDAIAPSLFAGRGGARRAGSVKEEPADEGAEGEAEGESGWGADDGGAPEE
>NC_021658.1|WP_044986960.1|12906972_12907308_+|nucleotidyltransferase-domain-containing-protein
MPMLHPPATEEVPEPLLFRIVEKMRPVEVWLFGSRARGTARPGSDWDLLVVLPDDAIDDDLDLMHAWQMVRDLRIPTDVYPVRQSEFEEARSHAGTLARTVMHEGRRVYAR
>NC_021658.1|WP_020741024.1|12905418_12906615_-|sigma-70-family-RNA-polymerase-sigma-factor
MGSDDALFETIWRTHREMLATYLLRLGVERQDLDDLMQEVLQGAYLGLRRFNPELGTLRTWLISIATHHVSHYRDRAHRRREELWSPEGFEPLVEESPSSESRAIDDDRHRALDALLAELRPQRRCVLVAHDILGMEMDEIAQALAIPVNTAWSRLRLARRDLEAADARRRARWRRRGWDETPVVLPAFVEGGQPASLLRDVLRDRVGGWLLRLGDLGASAPASAGAWGTAALGVAKPLCAAAAAGAVLAAGAALPSAGPAPARAQAGIGLHAALARRALDGAPSATGRHDSGAQRVTLAEAAESTAPPAAATATAATATAATASAAARRDRERPGDGGARLAEERRLVEEAAVALRAGHLAEAAELLTRHARRFPRGKLAERRDALLRELDAGSSTR
>NC_021658.1|WP_148314466.1|12903728_12905357_+|hypothetical-protein
MTWGTRGWHAAVRCALGAAASAAIGCGSAVSVCGCFPYDCAEHVACGASEAPETEVEPDAPGEPGAPADPEDIPCGGDPRDGAPKDGCGVFASSSLGDDANPGTRALPVRTVRRAIELSRQGARRVYACAEIFPEAVEVPAGTQIWGGLDCAHGWAFIGDRAQATLAPAPDLIPLRIEGGAGTSVVADVLARSADAAQPSGSSIAALVLPGATVTFLRSALVAGNGAAGAPGAPGADGGEGAAAPGADGRSGGDACSADVVPGAPSVTTACDDVDSIGGSGGDGAVSSGDDGRDGLPEPISSSMEWGHAGQGQTSGADCTDGMQDLSGAHGAHGRGAVGRGGMITRAGWEGVHGTEGARGISGQGGGGGGGTLGGVMYCGMSTATPKGGASGGSGGGGGCGGNGGQGGGYGGASIALISLSAGVTLHDTKLSSANGGNGGDGGAGQIGGEGGSRGSGGAARNGSLRGCDGGRGGQGGNGGHGGGGLGGPSIGIAYLLDPPELLGTLALRIGEPGKGGAGGRPDMIELAGQDGAVAEVLGFVQ
>NC_021658.1|WP_020741022.1|12902712_12903699_+|PEGA-domain-containing-protein
MDAYRDALEGHLGPALPIAKRAEVLGELGLCELALGAHRDAAEHLHLSLQHRSLLAVEQQRRFEAAQKQAEREVGTLFLAVSPRDAEVLLDGKSLGASRPTHVVFVEPGPHTIRARLAGYADATAALQAARGSSSSVTLTLPARTSSPAPSPEVSGAPAHAPAPAEAPGAPANTLRRIALGTAAAGVVLGVGFWVAAGVLDGVVDERAASLRARGGSGACNGTAFPTECKHQEFLIARRDGVGAAAIAVLVASGALGALAVSSYWWAPDTSPRPAIGLGPATADAPDTSPRVAIGLGPVDADAPGLSPGVTFQTSGPSTRTRRGCLPA
>NC_021658.1|WP_049949805.1|12901237_12902380_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MLAVLAWITACTAPSDGGGSAAAKADAPGQVHVARAAEGTAPAGASAAAPAPATAAALAVAPAPAAPAPAGSAHAGAAIPGGAAAEPASIAAGASAAPVEPPPPGSASAAPSVFPPQPLGIPLSLGSCSADMVLVGGSCIDRYEAHLVTDAGGELAVHPHFKRPEPGVRYVARSAPGVFPQAYISRVEAKAACAAAGKRLCTRREWQRACRGNGVHRYPYGPRGERGRCNTGKAHLLREVFGEHPPGGWSYERHFNSPELNQKPGFLARSGDHAGCASELGVHDMIGNLHEWVSDMVDHELVMRMQTEGVERRDQPWHEGNGVFMGGFFSTTSELGPGCYFTTIAHEPAYHDYSTGFRCCDDAELPAAPEPAGAIQRDGG
>NC_021658.1|WP_020741031.1|12915180_12916107_-|NAD(P)-binding-domain-containing-protein
MSARPAVGVIGGGFWGVALALAASRTGAEVLLYSRREHPQINDGPRIVRDHAEVARARLLVIAVPSNAARTALRALGDHMDGAHLVIHGVRGLEGEALKTVSDLVREETPARRVGALGGPVQEDELREGRPSAMVCGSRFPEVHAAVTAAFQSPALHVYTTPDLQGLEWASALVGCLAVGVGFAEQAGAGPGLLAALISRAVDSAARIAAAAGAEERTMLGLGGYGDLLASIRLAGRPEVILGKALARGRTLDEAVAEARLRVEAIPLIPRIVAFAKARRVDGGVFEALEAVLQGGEPRVVLDRMFAA
>NC_021658.1|WP_020741032.1|12916103_12917888_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MDSRAPIFGFNDARDEIVRTVVDRVIGATRDPLLAMNEAAYQEAKRLEGSRKPQDVRELGEWQRLARSLGRMHDAERRRRLRELAEEYAWDIAGNFDRRVYQLSSRLLPPVVSALLAPRKLVTVVRDPRKLVSLELLADRVLVQGPLAKLRSLVQRGTAVYVPTHLSNMDSIVFGYALERAGLPPATYGAGKNLFTNPVLSFFMHNLGAYRVDRRIRHNLYKDVLKTYSSVLLERGYHSLFFPGGTRSRSGGIERRLKLGLVGSAFEAYTRTLLSGRERRIFFVPATINYLITLEAETLIADFLSEAGKGRFIIEDDESSRIGRIASFLRKLLAMNAAVVIRFSEPLDPFGNRVDELGRSFDARGREVDPASYVKDQDGVPNIDGARDAQYARELGEEICRAYARDTVVMATHVVAAASFARLRSHAPAADLFTVLRQRDVLTVPRDDLAADVMALCDRLRALEQQGCVVLGEDVRLGSGGDIVERALRAFAGYHATPVLDSRPDGIAICDTNLLFYYQNRLAAHGVAWDVIAPPGVPSGLQVQPPLPPLAPSSPPPSFDEQQQQPRGASSARGGAAAARAGSAGSMNGAGGGR
>NC_021658.1|WP_020741033.1|12917953_12918709_-|hydroxyacylglutathione-hydrolase
MRILPVPCLSDNYAYLAAADGRREAIVIDPSEAEPVVAALEREQLRLVAIINTHHHLDHVGGNEALRQRYGDLPVYAHASDVGRVPAQTERVEEGTPVEVAGLTFRPLHVPGHTMGAVSYCVEDAVFTGDTLFIGGCGRMFEGTPEVMHASLSKLGALPVHTRVFCGHEYTVNNLRFAETVEPENEAVRRKLAAARAARERGEPTVGSTIAEELATNPFLRCGEASVRARFPGPTLPDVFAAVRRAKDDYR
>NC_021658.1|WP_020741034.1|12918876_12919881_+|hypothetical-protein
MASAEPSVRYRIGVDENGLGPRLGPMVVTAVLSRVTEAGWETAGRAPRGALAQRLGDSKQLVAHGDVSLGEAWARALVARGCGRGAAAAAPSSVDELIHAVALEDRAALRALCPGHVEAQCWSTEGEGFTAPDKLLRAIGRDLDKLADKGVEIVAVRSVLLCAKRMNDGARAGKNRFVLDLHAMERLILELGGLAGAEIFAVCGKVGGFGKYGSAFGPLAGRLHLALEEGRARSVYRFPGLGEIAFVRDSDASDLCVAMASMVGKYVREALMERVARHYQRAIPGLHGASGYHDPVTTAFIGATRLVRRAREIPDDCFERRAAEGEAPLEGGSP
>NC_021658.1|WP_063752173.1|12919985_12921140_+|bifunctional-methionine-sulfoxide-reductase-B/A-protein
MNWLRAARLFFALLLVASAALVACWRAGAAGEASKAAPGSKEAVTMSDRTYRKPSEEALRKQLTPLAYEVTQRDATEPPFRNAFWNNHEAGLYVDVVTGEPLFSSRDKFDSGTGWPSFTRPVEPSRVVERSDRAHGMVRTEVRSKAGDSHLGHVFEDGPAPRGLRYCINSASLRFIPLDRLEAEGYGAYRAQVEGRSRAPAAQDGANACAVPASGEAPGCKTTLETAILAGGCFWGMEELLRKIPGVLETEVGYTGGRTKDPTYRDVKTGDTGHAESVRIVFDPAKVSYAELLEKWFFRMHDPTTRNRQGNDVGTQYRSAIFVTTPEQRRVAEEVKARVDRSGKWRAPVVTEIVEAGQFTRAEEYHQKYLVKYPDGYTCHYMRD
>NC_021658.1|WP_020741036.1|12921456_12922863_-|dihydrolipoyl-dehydrogenase
MKTYDAIVIGAGPGGYPCAIRLAQLKQTTLCIEKEQPGGVCLNWGCIPSKALISAAHLYEKSQAGASMGIKVSGVELDANAMQDWKEGIVKKLTGGVRSLLKGNGADLMTGTATIVGPKRVDVTLPDGSVEQIEAKKAIVIATGSTTIEIPSFKFDGQSIIGAKEAVSLRQIPKRLMVIGGGVIGLELGMVYQAFGSQLTVVEALPDLLTGVDPDCTKIVERKILKRGGTIHKNAKAIGYEKQKDGSVGVKIQIEGKEQTIVVDTVLVAVGMRPTSKGLGLEKVGVTVDQRGFIPTDKTCRTNVPSIYAIGDVSGPPLLAHKATKEGEIVAEVIAGHKAAKDWVAIPGAIFTDPEIATVGLTEAEAKAKGLEVSVGKFPFSALGKAMALNETEGFVKIVADKKTKQVLGVHIVGPEASTMISEASLSLEMAAFLEDLSLTIHPHPTLGESLMEAAAHAMGAAIHIANR
>NC_021658.1|WP_148315049.1|12923026_12924112_-|3-methyl-2-oxobutanoate-dehydrogenase
MLSVLRDDGTLDPATDPGLADALLLRAYREIKRLRLLDARMLLLQRQGRVGFYGACTGQEATPIAAALALEPTDWIFPALRESVMMLVRGFPLRSYVAQVFGNSGDLLKGRQMPSHMSGRQVNQVSWSSCIGPQIPQAVGVAWAARLRRDRTVVVGFLGDGATSEPDFHSAMNFAGVFKAPCVMICQNNHWAISVPTDRQTASRTIAIKGRAYGVPSVRVDGNDVIAVYRAVSEAVARARAGGGPSFIEALTYRVGAHSSSDDPSRYRSQEEVDRWTARDPLLRLGRHLAARGLLDDAAEAALEAELNAEIAAAVAEVEAMDPPARETLFDDVYAELPWHLRDQRAELLRSPKAPAHGGGR
>NC_021658.1|WP_020741038.1|12924324_12924600_-|hypothetical-protein
MPRDNKLYSGFVNHDYILTFSIADEESRARLVALCAGPWQGDEVTPGTWEVSNTLSPDQMERAILDLMGDADRAAYYYLSDSKRMFRVLLG
>NC_021658.1|WP_020741039.1|12924708_12925323_-|DUF4149-domain-containing-protein
MNDDAQFSEADLAPSPEERAASRRSLIDRVAASVAALAAGAWAGGVVTLGTCAAPFVFRLTPGPFSGDAMSAAFARFDQLALGAAVILLGAEVARTWAAGRRGASRAARVRRVVAMAMAGCAAYVGLALTPRIAALHREGARRGEGERGMELERAHRRAELVSRSEVFLGASLVALHVFTLGARRPEEDEDDEDAAAPLPPGPR
>NC_021658.1|WP_020741040.1|12925319_12926366_-|HEAT-repeat-domain-containing-protein
MFGPAPAKRTLEAALRDVASQKPAVRVEAVTDLVPYAATERERVLRAIEGALRSDAHAAVRAAAAIALADTKAVEALPALLLAVEDEDPNVRQMAITALGEIGDVRATGRLRRALSDERPEVRFQAVIAFPRVCAQAADALEAVMEATHDGDPLVCHIALRMFEELGEPNGELPPPCMARARALLGHASPLVRATAAVVTARFGDPAGHAVLVEIVEGKLRDVDHEDEAAAIELCGELGLAASRGALERRAFGRRLGLGRDPLRWHARVALARMRHERAIREILSELGAWDRHRRTLAVAAAGRARLAAARPAIEAMRGDDRKADQGAVEEALAAIGSDGSDGSEVDA

Crispr_ID: NC_021658_61

• CRISPR_ID: NC_021658_61
• CRISPR_location: 13327224-13327304
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_61

Consensus_repeat	Method
CTTCTCGGCGATCGTGCCCGCGCG	CRISPRCasFinder

spacers of NC_021658_61

>61.1|13327248|33|NC_021658|CRISPRCasFinder
GCCGCCGCGCCAGGCCCCCTCGGGTCACCCGAG

CRISPR arrays and Neighbor proteins around NC_021658_61

CRISPR arrays

The CRISPR arrays of NC_021658_61

>merge|NC_021658|61|13327224-13327304|CRISPRCasFinder
CTTCTCGGCGATCGTGCCCGCGCGGCCGCCGCGCCAGGCCCCCTCGGGTCACCCGAGCTCCTCGGCGATCGTGCCCGCGCG

>NC_021658|61|54|13327224-13327304|CRISPRCasFinder
CTTCTCGGCGATCGTGCCCGCGCG	GCCGCCGCGCCAGGCCCCCTCGGGTCACCCGAG
CTCCTCGGCGATCGTGCCCGCGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020741323.1|13333252_13334059_-|diaminopimelate-epimerase	unknown	unknown	gnl|CDD|234768
NC_021658.1|WP_020741328.1|13337021_13338134_+|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl|CDD|235655
NC_021658.1|WP_020741317.1|13322459_13323146_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044987023.1|13308710_13310912_-|response-regulator	unknown	unknown	gnl|CDD|236901
NC_021658.1|WP_020741311.1|13312354_13315108_-|aconitate-hydratase-AcnA	unknown	unknown	gnl|CDD|236445
NC_021658.1|WP_044987024.1|13329713_13331333_-|DUF4388-domain-containing-protein	unknown	unknown	gnl|CDD|373017
NC_021658.1|WP_080682618.1|13315169_13316045_+|SOS-response-associated-peptidase	unknown	unknown	gnl|CDD|376837
NC_021658.1|WP_020741321.1|13328441_13329554_-|alanine-dehydrogenase	unknown	unknown	gnl|CDD|240630
NC_021658.1|WP_020741324.1|13334055_13334394_-|YggU-family-protein	unknown	unknown	gnl|CDD|376843
NC_021658.1|WP_044987026.1|13335649_13336264_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020741313.1|13316346_13317135_-|hemerythrin-domain-containing-protein	unknown	unknown	gnl|CDD|376622
NC_021658.1|WP_020741315.1|13317563_13319870_-|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl|CDD|293767
NC_021658.1|WP_148314520.1|13327332_13328424_-|isocitrate/isopropylmalate-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223549
NC_021658.1|WP_020741318.1|13323325_13323589_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314518.1|13320093_13321917_+|ATP-binding-protein	unknown	unknown	unknown
NC_021658.1|WP_020741319.1|13323721_13327165_-|response-regulator	unknown	unknown	gnl|CDD|381116
NC_021658.1|WP_020741322.1|13331369_13333256_-|diguanylate-cyclase	unknown	unknown	gnl|CDD|143635
NC_021658.1|WP_044987025.1|13334782_13335568_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020741327.1|13336577_13336907_+|cell-division-protein-ZapA	unknown	unknown	gnl|CDD|377476
NC_021658.1|WP_020741310.1|13310917_13312219_-|serine--tRNA-ligase	unknown	unknown	gnl|CDD|235461

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020741323.1|13333252_13334059_-|diaminopimelate-epimerase	gnl|CDD|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	2.19571e-83
NC_021658.1|WP_020741321.1|13328441_13329554_-|alanine-dehydrogenase	gnl|CDD|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NC_021658.1|WP_044987023.1|13308710_13310912_-|response-regulator	gnl|CDD|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	1.20779e-43
NC_021658.1|WP_020741311.1|13312354_13315108_-|aconitate-hydratase-AcnA	gnl|CDD|236445	PRK09277, PRK09277, aconitate hydratase AcnA.	0
NC_021658.1|WP_044987024.1|13329713_13331333_-|DUF4388-domain-containing-protein	gnl|CDD|373017	pfam14332, DUF4388, Domain of unknown function (DUF4388). This domain family is found in bacteria, and is typically between 102 and 135 amino acids in length.	5.97357e-28
NC_021658.1|WP_080682618.1|13315169_13316045_+|SOS-response-associated-peptidase	gnl|CDD|376837	pfam02586, SRAP, SOS response associated peptidase (SRAP). The SRAP family functions as a DNA-associated autoproteolytic switch that recruits diverse repair enzymes onto DNA damage. We propose that the human protein Q96FZ2:UniProtKB, the eukaryotic member of the SRAP family, which has been recently shown to bind specifically to DNA with 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxycytosine, is a sensor for these oxidized bases generated by the TET (tetrahedral aminopeptidase of the M42 family) enzymes from methylcytosine. Hence, its autoproteolytic activity might help it act as a switch that recruits DNA repair enzymes to remove these oxidized methylcytosine species as part of the DNA demethylation pathway downstream of the TET enzymes.	5.03401e-72
NC_021658.1|WP_020741328.1|13337021_13338134_+|8-amino-7-oxononanoate-synthase	gnl|CDD|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	3.73254e-137
NC_021658.1|WP_020741313.1|13316346_13317135_-|hemerythrin-domain-containing-protein	gnl|CDD|376622	pfam01814, Hemerythrin, Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor hemerythrin binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial NorA is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus the iron-sulfur cluster repair protein ScdA has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.	4.78585e-10
NC_021658.1|WP_020741315.1|13317563_13319870_-|sulfatase-like-hydrolase/transferase	gnl|CDD|293767	cd16148, sulfatase_like, uncharacterized sulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.	7.23152e-21
NC_021658.1|WP_148314520.1|13327332_13328424_-|isocitrate/isopropylmalate-dehydrogenase-family-protein	gnl|CDD|223549	COG0473, LeuB, Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism].	6.91287e-128
NC_021658.1|WP_020741324.1|13334055_13334394_-|YggU-family-protein	gnl|CDD|376843	pfam02594, DUF167, Uncharacterized ACR, YggU family COG1872.	2.96654e-25
NC_021658.1|WP_020741319.1|13323721_13327165_-|response-regulator	gnl|CDD|381116	cd17574, REC_OmpR, phosphoacceptor receiver (REC) domain of OmpR family response regulators. OmpR-like proteins are one of the most widespread transcriptional regulators. OmpR family members contain REC and winged helix-turn-helix (wHTH) DNA-binding output effector domain. They are involved in the control of environmental stress tolerance (such as the oxidative, osmotic and acid stress response), motility, virulence, outer membrane biogenesis and other processes. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	7.09346e-23
NC_021658.1|WP_020741322.1|13331369_13333256_-|diguanylate-cyclase	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	9.36137e-06
NC_021658.1|WP_020741327.1|13336577_13336907_+|cell-division-protein-ZapA	gnl|CDD|377476	pfam05164, ZapA, Cell division protein ZapA. ZapA is a cell division protein which interacts with FtsZ. FtsZ is part of a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the bacterial cell cycle. The interaction of FtsZ with ZapA drives its polymerization and promotes FtsZ filament bundling thereby contributing to the spatio-temporal tuning of the Z-ring.	2.80281e-09
NC_021658.1|WP_020741310.1|13310917_13312219_-|serine--tRNA-ligase	gnl|CDD|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0

Protein sequences

>NC_021658.1|WP_020741319.1|13323721_13327165_-|response-regulator
MEHAGPRSNAAGEARHERLGGARAEFVANLGRRVAELRAVVRRIEADDDAPRLIEDLKRRLHSLGAGARLLRFARVAERLAEGESALVASAGGRLSGETAAVLGKVLEELPALAWGQAAMGETAAAPREQAMASREQVIASREPAAAQNTRAGAAGPAGARSAGAGQEEAAGAGGAKGQGSTWIAGVSNGRALAPAPLTLDDEEDASARPSSPRSAEQARAVEAQEAAPLEAPITVLVVGGAPLAEALDPEGAGAGPSFEVERTDEIDTAIDLARAFAPDVVLLDADLPGARGLAEALAADPLTDLVPVVAVGRFARPEDAAPYVALGAARALAKPASPDALRRAAAEAAASCVRLRQPARAPLGAVSLDDLGARLAEELRRGLCDAAEPRSRGAHVDLGDGAEVLAALWGAVARIRDLVTIRSHGGVRFTPNGPEGALPLAPWMTAPGAPEGERSRLHSEIRARGPARGAASAAAPIDAALDAMDIVVADDDPAVTWFLAGVLRAAGAKVHEAHDGARALDLAYQTTPDLVVSDVLMPRLDGFALCRALKRDVALRDVPVILLSWKEDLLQRLRELGAQADGYLRKEASAAAFVQRVNEVLRGRRRVAERIATGGEVRGRLDGMTTRTLLSLACARRPDALVSVRDAAFLYEVLIKDGRPAAATRTAQDGTFHRGPSVLAALLGVGSGRFAVAPAPEDELRAPPRPGFEGTLAEQLVPAIAAARAAQRLLHGPPLMQVERVILDLEGMGATTDATPEPARALLRALARGSSPRSIITSGEFAASLVEDVLNDVAARGWVRRVIGREAEDLLAPAVVREEETLRGVRRASERAAPAVTLPPELGEGGAASSRAPVELGDDQLTVVPGSVAPVSAAPASGAAASIPVVSVVSAPGSAASIPVVSAAPASWSAASIPVVSAAPASGSAASIPTVSVDGEDEIAAPSARRALASARIPSDLAELQGDVASARATWTTPAEAAALAAGVTPAVPGVAPAPAPRRPEATLPALEVPKPERLLTLGSLPPPPVVEAPAPPPAALRAPAPLAARGAASAPSPTVDESPTPRRVRRPSAYVPTPPPPARDNRMTMWVLFAVAAFVFAVAARLSRDHELQGAPPPAEPPSPPAAEPPAAAAPGAAATPSWTRLLCG
>NC_021658.1|WP_020741318.1|13323325_13323589_-|hypothetical-protein
MLPEDLPLATGHKVPEGHGMLEVIAGSGDTLFVDGRKVGTGSVKLPLAPKDGAYEIRAKLRDEERVRFALVKAGRLTRLRIAPPWRR
>NC_021658.1|WP_020741317.1|13322459_13323146_+|hypothetical-protein
MAINTIHHDDSLDHIWSVLVYEEARLLTDKDASDLAPEAGALVERWAQVNAGQRSAWRAEIVAQAGVDTEDDLLDDTVDELDNELLRAFRDRDAPQRRRYFKKARHEIVRLGLESQLEVVRAWPASLKSEREAALQALGARLEEDIARGDVAVEERLRAAAATADQRVREIVRFVDDINAARRTRYGLLIQRAEERRLPKDWPGRFFKKSSQGSKKAKTAPAVENPPA
>NC_021658.1|WP_148314518.1|13320093_13321917_+|ATP-binding-protein
MPVGRKGVGDDVPGRGQSGSVGARLNRVRPAELELVPEALSCRAPRVTKSSAMADLYDELEFPPRAEYLDQYKNYQVDIAHWQRLAGQFQKAFRQVYARRSAAVLLVHGPQGSGKSMFSARLAQDHERTRGGAFAPDLRNNLWHALVATDQPDERAIEDVTRDTVLRLVDEHKSQNWLEELRGFATSDKSRVRLIVCDDMHKDSMMRPWTEMSPRDFYEARQAGPDAILAYLAERLNDACRHEFQRSIFVMLSNDQAWIEKLHGHLERWYQGLSTVLTLPVPEAPTLERIVRINTNRLNKVSYWYCLDAAQTEQRKEVRRVLMEGSGFTSSFHAVSQSLDAASRRMGRPGNPNVLTLVTLGSEFAEVQTFLNDREIDAEPGHGASPRHLGVWEMRGPWASKIVRKPSRELLRRARMLESEFMLRWVSLDMVGTYALLQPPAAGDLGDELLLLILRRPSIGTLKSTRDAWRSECAALDTRLDNPPFAAVEVEKLFKDFMTLGQRRSTLYEPALRHRAGAARLFSRGFAVYASLKPDMIVEDPGPPKHGQYAVCALTSADSDDPKDIADAIRRAGHSVEFTAFLRNNLVGIEDYLRDKIERYAGMLESV
>NC_021658.1|WP_020741315.1|13317563_13319870_-|sulfatase-like-hydrolase/transferase
MRARVIRPYHPSAALTLLAAAAALLSGCTGCESTRELPAGATAPASASPAATPLPPARDLVHLVDELRNCDIEHRGLLFDTGANALLGRFAWQGTVPTGIDAVEHAGSTWARISERQIKLTFLLPSASPIFVSARAVGLASRYATISLDDQLLGTLRFQRDQIRIASTPTTTLPADPGLHTLTIRFSGRLRDGESFADIDWVRVGIPDEDPATYGPPTLRDVVAPAAALSGVPHRSIALRAPGAVRCTFRPSKVTRLRTAVGVLGAGEGDAEIRVLRDGQEPLALHRVHVEGGDKATWTDVELPLAPFEGSLITLELRATAAARGGRILFGDPVLAGSPEPPPPVRAARAVVIVALNGVERPDLPPWSGRPEPHLATLSELATSATTFDHHRGPSTVVSAVIASLLTGLPPPAHTVTDTGARLPARMTTIGAIASDSSIRTGFFTGVPTTFRAFGFGPGWSRVLEHPPTSGEPATTPIDAAAAWISETVRQDAGNRLLAFVHARGGHPPWEVGPKELNALKPADYAGPIEPRRAAQVLARLRNRRRDVLSPDDRDRIRDLFSIALAGQDRALGNLIGTLKAAGLWDETLFIVTGDLASGRSDGTLYAESLDLQEPVLTLPLYVHFPGDLYAGQRISAPTEIIDITRTAVAALGLSFSREPLGKDLAAVASGLQGVERDPQIAALGARYSTRWGNLVLSGRLGVPPFLCDLNVDPTCAFNRREVMPLATLSLFRRTVTFDLSVRAPAAQREPATIDAETAAVLNVWGAQ
>NC_021658.1|WP_020741313.1|13316346_13317135_-|hemerythrin-domain-containing-protein
MKATDLLKEQHREVDELFDRIAQADTNEIGALRDELVASLVGHAAIEEELFYPATREALGASPLILTSYEEHSLVEIMLQKLLSTEPGDETFHARLGVLKELVRHHVEEEEQELLPQAERAMGADRLEELGARLEARFDQVREGNVEALLSQIVAKSMAAAGVRRTRAAKPAARKAATKRPPAKRASTQRAEPARGAQKGRRGAAATTGRKKAADAAPAKTGRAAPARKTGRATTSRATASRPAKTSRTGRKGGRTSSASAR
>NC_021658.1|WP_080682618.1|13315169_13316045_+|SOS-response-associated-peptidase
MCARFTLAVPDFASLVAMLEAYLGAGAADGGPARAIAVDPKAAALYRPRYNIAPSTVHPVLRAQGGQRELVAATWGFTGRFAGGGAAPSLLANARAESARTKPTFRGAFAARRCVVPADGFYEWSGPKGARRPTWFHPAGGGMLRMAGLYQPAKDPDAGDIDVRFTILTTEASADVAQVHDRMPVLLAPEDVDLWLGAGEESDADRVEALLRPAPRGSLAARAVSTRVNAVGHDDPSLLEEIAAEAAAPKAAAPKASPAKAAAPKAGGTLPLFDLDAGAGPSVPSGRTPRR
>NC_021658.1|WP_020741311.1|13312354_13315108_-|aconitate-hydratase-AcnA
MVDSFGTKSTLTVQADTYTYYKLTALAQGGASLDKLPFSLRILLENLLRHEDGRVVRKDHVEAVLNWDPKARPSQEIAFHPARVLLQDFTGVPAVVDLAAMREALAKLGGDSLKINPLQPVDLVIDHSVQVDKFASSTALKVNAALEFERNQERYAFLRWGAQAFTNFRVVPPDQGICHQINLEYLAGAVMRQGALVYPDTLVGTDSHTTMINGLGVVGWGVGGIEAEAAMLGQPLSMLIPEVVGFKLHGSLPEGATATDLVLTVTQMLRQKKVVGKFVEFYGPGLSALSLPDRATIANMAPEYGATIGFFPVDDETIAYLRFTGRPASLVALVEAYYKEQGLFRTDSTPDPVFSDTLALDLGDVEPSIAGPKRPQDRVRLRDAKRTFRASLQGMLEKEFAAAEPAAVKSFLEEETGAAAARAPALEKVMRPAEIAEGDTRYTLRHGSVVIAAITSCTNTSNPAVMLGAGLLAKKAVERGLTVKPWVKTSLAPGSKVVSDYLQQAGLLPYLEALGFHLVGYGCTTCIGNSGPLPDVIGDTVRHNDLVVASVLSGNRNFEGRINQHVRMNFLASPPLVVAYALRGDVDADLFKEPVGTDRNGEPVYLKDIWPSSAEVNEAIRTAVRPEQFQAQYENVFAGDEEWQKLSVPGGQTFVWDESSTYVRRPPFFEGLSKDPSPLGDIRSARVLALLGDSVTTDHISPAGNIAKNSPAAKYLVEHGVAPADFNSYGARRGNHEVMMRGTFANIRLKNLLRPGEEGGITVHLPDGEKTTIYDAAMRYKAEDVPLLVIAGAEYGTGSSRDWAAKGTKLLGVRAVIAKSFERIHRSNLVGMGVLPLEFAPGEDAGTLGLTGREVFEIAGIADNLTPGKKLNVVATGEGGKTTTFTVTARIDTPNEVDYYQHGGILQFVLRSLGATA
>NC_021658.1|WP_020741310.1|13310917_13312219_-|serine--tRNA-ligase
MLDPRYVADHLDEVRASLARRSPAAAATLGDDFASTVSSRRSRIQELERWQAERNAANDAMARLDKKSPEFAQKRDELKALSAKIKEAEQVASELEKRLTELLAVVPNLPDPSVPDGAGDEDNVVVRTWGEKPSFSFTPKNHWDIGTALGILDFERAAKLSGARFTVLLGAAARLERALISFMLDLHTREQGYLEVLPPFLVKDSALFGTGNLPKFADDLFKTQKSDPERAYDLYLIPTAEVPVTNLHADEILDGASLPIAYAAYTPCFRSEAGSHGRDVRGLIRQHQFDKVELVRFSAPEDSPRQHELLTAHAEEVLKRLGLHYRVSALCTGDLGFGSQKTYDLEVWLPGQGVYREISSCSNFGEFQARRAQIRYRPEPKAKPRLVHTMNGSALAVGRTVIAILEQYQQADGTVVVPEPLRAFMGCEVLRGR
>NC_021658.1|WP_044987023.1|13308710_13310912_-|response-regulator
MGADEEAKRELPEPRGGREPGEGERRSQLPESRRGRELGEGERRSQLPESRGGRELGEGERRPQVHAPSTPIETSMALARRRLLELCKRHKDELIDDWIENVLALPPERGRYTDRPVGEVTENVRSWLAAFTRILEDGSETLLDEFITHLVEQRYATGYSISGPLIAASEFRTAVAGVLDTTHDDGDADGTSSIDVLRAVDALLLQFEHRFAEAYAQRSLFASEERYREIVELSSDVLATIDQEGMLTRLNVRFEVLFGHSRQAWIGRPITALAVAADVPALRALVMSASRAEAPREATIRCGTRAGLTKVMTVRITRLYGEDASLALMRDVTEEVARRAQILHSEKLASIGQVAASVAHELNNPMAWVMANLEQIRSGAHKLVSAARPVASGSYEDLLRAIDLIDRSCHEALAGVERMRDIVTDLNLFSSSSERKPERVDLVDVIELALRMTGPQLSQLCRIERHYGEMPPLVGYPGKLSQVFVNLFINAAQAMPNRPRDENLVRVSARFDDGVHHVEVEDNARGMTPEVVERIFDPFFTTKEESARPGIGLWVSRNIVEEQHGTMTVSSKPGIGTVFTIRLTGLNPADLPALRPPPEPPRLSSRGTILFVDDEPMLLNAFARAFEERHEVLVAKSGHEALDLLRDRGGRIDAIVCDLLMPQMSGMALYDEIGERFPQLQPKMAFMSGGAFTPSAREFVERVDNPKIAKPISLDDLERVIADLLSGGQKRGH
>NC_021658.1|WP_148314520.1|13327332_13328424_-|isocitrate/isopropylmalate-dehydrogenase-family-protein
MAAGKKKKIAIIGGDGIGPSVTAEARLLLELYQARAGLPIDLWDLDLGADRYLRDGTTFPNQIQVAIQRECSAVLLGALGDPRVPNLEHARDILFGMRFGYDLYANVRPVRALSDRLVPLKGRAAKDIDFVVFRENTEGIYVGMGGQFKRGTPDEVAINEDVNTRKGVERIIRAAFDYARATGRTRVTMADKSNAMRHAHELWLRVFHEVRAQYPEIQSNHVYVDALCLYLIQDPSQFQVIVTNNLFGDIVTDLGAALQGGLGMAASANVHASDPARVALFEPVHGSAPPLAGKDVANPFAAMLTAGLLLAHLGWPEEERRIERWVSQALDQGMCTADVGGTLGTRAAGAWVREQIAAELGSP
>NC_021658.1|WP_020741321.1|13328441_13329554_-|alanine-dehydrogenase
MLIGVPREIKTREYRVGMTPAGVRAMVGHGHRVLVESGAGEGSGLSDEAYARAGAVIARSAAEAWSADMVVKVKEPLPSEYGHFRPGLVLYTYLHLAAEPDLTKELARRGVTGVAYETIQLEDGSLPLLRPMSEVAGRMAVQVGASCLEKERGGKGVLLGGVPGTRRGRVAILGGGVVGRNAATIAVGMGAQVTVLDVRAETMSYLEDVFGGAIETLYSNAENIETMCERADLVIGAVLVPGAKAPLLVTEDHIRRMEKGTVVVDVAVDQGGCIATCRPTTHDHPTYEVHGVVHYCVANMPGAVSHTSTWALTNTTIGYAVAIANQGIAAAAKADRAVALGINTHGGHVTYGPVAAAHRLEYVPVERALG
>NC_021658.1|WP_044987024.1|13329713_13331333_-|DUF4388-domain-containing-protein
MVDSDVDALGALASALRARGLTVTNANGAFEAVEQAFKRRPDVVLAARALDEDSALADAFAAVPDLAETPILFVVDGAEGELGPDDVLRGDVDHIVSRITEASPRGSKPTALQEIRGDLQQVPLVDLLQLLAMNRRSGVLGITTPAGAGELRLSAGEVIDAVYRRLEGEKALYRLLGERDGQFAFSPGEPTSARRLIAPTSRLLMEALRQVDEVQRRRVELAPAGEAFLVTEPSSDDLDLTPLPSHELFSAVAISGGAVAADDASAATSVPDITAPAPLAMPAGAARGGRGSMPPPPTLRAAESTAPKPEATRSPTAPPPSLGEPTERALVAEKLTALLQMPHNLDELLDEIGAPDLLILEVLMELTEAGKIRRISLADLTTPFAPPEHFPVLRSLVTRLSRPGFAPPPHLVIAASARRMTMLSHAVRRIADANVPAEPPPHAPLPRPLGVIRLGDGVELALIGLPTEESFAPTWALALHGAAAVVRLGDAREDALAAHCEALELLLLDAEAMMGPLDLASPGQITLLVRAALEAAAGV
>NC_021658.1|WP_020741322.1|13331369_13333256_-|diguanylate-cyclase
MTASVEGVWSPSRAPVHEISLKVLAVIADEATHTLFSRVVTSDELMLASDLAEGIALAETAAPDVAFIDVGLGDGAGLAMVHHLKALAPEATVFALATRAQLEAGAHAVALGGAGLFLLPLGGDEVLNAVGSVRVRFVERALRVQLEQESARSARAAGWIARVAELADARDRNAAAQQVAEVFVEATGAAAAAVYLTVGERSTELTRSALTGPLDRAPAYGSEADILDFARREQLIVVPLALRRLSAGHLLLQKEPGRSSAFPSVRRPDSSVSTSRRAPLLDGLVKLLATQATTALALLGERERSTGGAAMKDPASSAYSFAYYVDVAGREIDKAKRHGRRFTIATIVIEPDATAAPERPDDLSYWRATPPPPANGLNAGQVAEHLLRAVRDTDILARVDENEFHLLMPETAGLEAHACHRRMLSRVAGSEKRAGYLPKGLLVGLATFPHDGQGLAQLLRIARRRAEATKSSILHRVPQDRRSIGEIFSLLVREAPSAEGPSAISAPRALDLSVTDTVLLATSVIRNALRGGAVLILVAHHDGLSLGAQVKALLASPRDDVVVHALDLRSAPGCDDIEALCVLAEHGAYALVGRNQGGFVKGIHAADPLLADFLAERLGRAAGLRVFG
>NC_021658.1|WP_020741323.1|13333252_13334059_-|diaminopimelate-epimerase
MKENVVRFEKWEGLGNDFILVEAVPMTAEAARRLCDRRFGIGADGVLVIDRERRERPTMQVWNADGSRPEMCGNGIRCVAAYLVSRGTPQKALTIATDAGDKRCEVTRAGDRFDVLVGMGRARLGEPLVVSALGAEHRFATVDVGNPHAVTFDPYTEDAIDELGPIVATTPAEGINVEFCRARPTEQAEGACIDVTVWERGVGRTLACGTGACAVAAAACAQGRAPYGAPLRVVLPGGSLRITVAPGSLELLMQGPARRAFSGEVVIA
>NC_021658.1|WP_020741324.1|13334055_13334394_-|YggU-family-protein
MSKPEESDPVAAWSRLAITERAEGVRISVQVRPKSSRSAIVGVREGALDVSLTAPPVDGAANAELVKLLSRALDVRQSDVQIALGASGRSKVVAVRGLNETEARARLAGAKR
>NC_021658.1|WP_044987025.1|13334782_13335568_+|hypothetical-protein
MADEGEGSVAATSGLARRLCALALLAVSGGLLASACADNESSLFVRMRMARTGDCTVTCGADEPFWTEDTVDAAYAGSHSATLLVGNQIVQRGDPDVLRTETSRVHLYEAEVRVDDIEGNAVTEGYVVPVTGMIDPGTSSDAGYNCAEVLLLDGATMDNLRRRAASLGRDVQVVATVVVRGRTLGGQEVETAEWSYPIRVCFACSRCVDVSPATCCVSSASEECEDNDEVVGTCSGQRGPQDCRNLGQTCAAYIESVRRTL
>NC_021658.1|WP_044987026.1|13335649_13336264_-|hypothetical-protein
MPTAGRPAALLAALLGVVLAHGTARAEPQASVGVTLGAAGTGLERRWWDSTAFHAGLRGDVLFGRGANDDFGVGPYAEVLTHGFDELQAGAGVSALAPVLDLFPLIVSTGVYGRWSDDADALEPGIAAAVFWGARSYNFHSPYVMSTGLLAQMRLGLGASKETAIVLAAQLDVALLGLPFVYLFNVLTGPSPEAAPVRRAEAAR
>NC_021658.1|WP_020741327.1|13336577_13336907_+|cell-division-protein-ZapA
MARRTVQLRVGGQTYRVVTSASDEELQRLAAVVDQKLATVVPAGRAVTPQAMLLAAIALAHDLEQERSRTAMIAGRARDAFGRILQRVDAVLGVGPDSPSSGEANGSAP
>NC_021658.1|WP_020741328.1|13337021_13338134_+|8-amino-7-oxononanoate-synthase
MDALRHLQDELSELDRAGLLRTPPATASGAGMLVLCSNDYLGYAALPWLSEGGAASGAGASRLVSGTHEAHLMAERELAAWLGMEAALLFSSGYAANVGTVAALARPGDVIVSDALNHASLIDGCRLSGAAIEVVRHVDAGAVESALVRGRGARRRWVVTESLFSMDGDSPDLRYLRELCDRHDAALVVDEAHALGIHGPRGAGLCSEVGVRPDVLIGTLGKSIGLHGAFVAGSSTLRTYLWNRARSFVFSTGISPMVALASVDRVRRAAADDAGRSRLATVTRQLRAGLHALGAPLLPGSSGPILPWLLKSPGAAVEMSQRLAREGILVQAIRPPTVPAGTSRLRITASASLSEADVERALAGFREALR

Crispr_ID: NC_021658_62

• CRISPR_ID: NC_021658_62
• CRISPR_location: 14280562-14280706
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_62

Consensus_repeat	Method
GACGGGCGACGGGTGCGGCGCGAGCTGCCGGTGGGAGGTCTGCGGCAACGCG	CRISPRCasFinder

spacers of NC_021658_62

>62.1|14280614|41|NC_021658|CRISPRCasFinder
ATCCTCGATCCCGGCGAGGACTGCGACGACGGCGGTGTCGT

CRISPR arrays and Neighbor proteins around NC_021658_62

CRISPR arrays

The CRISPR arrays of NC_021658_62

>merge|NC_021658|62|14280562-14280706|CRISPRCasFinder
GACGGGCGACGGGTGCGGCGCGAGCTGCCGGTGGGAGGTCTGCGGCAACGCGATCCTCGATCCCGGCGAGGACTGCGACGACGGCGGTGTCGTGACGGGCGACGGGTGCGGCGCGAGCTGCCGGCGGGAGGTCTGCGGCAACGCG

>NC_021658|62|55|14280562-14280706|CRISPRCasFinder
GACGGGCGACGGGTGCGGCGCGAGCTGCCGGTGGGAGGTCTGCGGCAACGCG	ATCCTCGATCCCGGCGAGGACTGCGACGACGGCGGTGTCGT
GACGGGCGACGGGTGCGGCGCGAGCTGCCGGCGGGAGGTCTGCGGCAACGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_187346074.1|14285966_14286920_+|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NC_021658.1|WP_148314618.1|14282822_14285882_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_063752111.1|14297963_14298698_-|hypothetical-protein	unknown	unknown	gnl|CDD|177676
NC_021658.1|WP_148314616.1|14276540_14277206_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044987177.1|14273710_14275081_+|phenylacetate--CoA-ligase-family-protein	unknown	unknown	gnl|CDD|224458
NC_021658.1|WP_044989854.1|14290978_14292013_+|hypothetical-protein	unknown	unknown	gnl|CDD|308585
NC_021658.1|WP_044987175.1|14266029_14267112_-|histidinol-phosphate-transaminase	unknown	unknown	gnl|CDD|235064
NC_021658.1|WP_020741999.1|14267154_14267733_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314619.1|14296306_14296879_+|transposase	unknown	unknown	unknown
NC_021658.1|WP_020742000.1|14267729_14268842_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379114
NC_021658.1|WP_148314615.1|14269439_14273399_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_044987179.1|14286954_14288136_-|hypothetical-protein	unknown	unknown	gnl|CDD|275056
NC_021658.1|WP_020742004.1|14275077_14276268_+|glycosyltransferase	unknown	unknown	gnl|CDD|340836
NC_021658.1|WP_020742012.1|14291970_14292912_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176114
NC_021658.1|WP_044987183.1|14297017_14297959_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293841
NC_021658.1|WP_187345819.1|14293934_14294684_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|180440
NC_021658.1|WP_044989848.1|14277130_14278231_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044987181.1|14288393_14290631_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380491
NC_021658.1|WP_148315080.1|14278422_14279775_-|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl|CDD|225114
NC_021658.1|WP_148315079.1|14265189_14265972_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_187346074.1|14285966_14286920_+|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00608484
NC_021658.1|WP_148314618.1|14282822_14285882_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	7.17453e-83
NC_021658.1|WP_063752111.1|14297963_14298698_-|hypothetical-protein	gnl|CDD|177676	PLN00042, PLN00042, photosystem II oxygen-evolving enhancer protein 2; Provisional.	0.00208189
NC_021658.1|WP_044987177.1|14273710_14275081_+|phenylacetate--CoA-ligase-family-protein	gnl|CDD|224458	COG1541, PaaK, Coenzyme F390 synthetase [Coenzyme metabolism].	6.20439e-59
NC_021658.1|WP_044989854.1|14290978_14292013_+|hypothetical-protein	gnl|CDD|308585	pfam03022, MRJP, Major royal jelly protein. Royal jelly is the food of queen bee larvae, and is responsible for the high reproductive ability of the queen. Major royal jelly proteins make up around 90% of larval jelly proteins. This family also the sequence-related yellow protein of drosophila which controls pigmentation of the adult cuticle and larval mouth parts.	7.06453e-14
NC_021658.1|WP_044987175.1|14266029_14267112_-|histidinol-phosphate-transaminase	gnl|CDD|235064	PRK02731, PRK02731, histidinol-phosphate aminotransferase; Validated.	0
NC_021658.1|WP_020742000.1|14267729_14268842_-|AAA-family-ATPase	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	9.77281e-15
NC_021658.1|WP_148314615.1|14269439_14273399_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.59266e-86
NC_021658.1|WP_148315080.1|14278422_14279775_-|sigma-54-interacting-transcriptional-regulator	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	8.81688e-79
NC_021658.1|WP_020742004.1|14275077_14276268_+|glycosyltransferase	gnl|CDD|340836	cd03807, GT4_WbnK-like, Shigella dysenteriae WbnK and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.	7.45347e-123
NC_021658.1|WP_020742012.1|14291970_14292912_-|LysR-family-transcriptional-regulator	gnl|CDD|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.51972e-75
NC_021658.1|WP_044987183.1|14297017_14297959_-|MBL-fold-metallo-hydrolase	gnl|CDD|293841	cd16283, RomA-like_MBL-fold, Enterobacter cloacae RomA and related proteins; MBL-fold metallo hydrolase domain. Derepression of the romA-ramA locus results in a multidrug-resistance phenotype. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	7.68517e-42
NC_021658.1|WP_044987181.1|14288393_14290631_+|substrate-binding-domain-containing-protein	gnl|CDD|380491	cd06267, PBP1_LacI_sugar_binding-like, ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. Ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. In most cases, ligands are monosaccharide including lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. The LacI family of proteins consists of transcriptional regulators related to the lac repressor. In this case, the domain sugar binding changes the DNA binding activity of the repressor domain.	1.1128e-66
NC_021658.1|WP_044987179.1|14286954_14288136_-|hypothetical-protein	gnl|CDD|275056	TIGR04211, hypothetical_protein, SH3 domain protein. Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.	0.000390931
NC_021658.1|WP_187345819.1|14293934_14294684_-|SDR-family-oxidoreductase	gnl|CDD|180440	PRK06172, PRK06172, SDR family oxidoreductase.	2.80986e-84

Protein sequences

>NC_021658.1|WP_148315080.1|14278422_14279775_-|sigma-54-interacting-transcriptional-regulator
MLIFSADSPRCDVLPLEDGEIELGRCEVAGVHLDDQRMSRRHARVRWLGGTWQVEDLDSRNGTWLDGVPLTGARAGADFRIVRTGWSVFLLLADVEPFRAGVSRAGGTIRGATLARTWDAIDRAARLGTTLHIAGESGTGKEHAARAFHALGRRRDGPFVPVNCAAIPAGLAERLLFGARKGAYSGAASDADGYLQAAHGGVLFLDEVAELDLGVQAKLLRALEAKEVLPLGASRPAQVDFALVSATHKDLRAQMAAGMLRDDLYFRIGRPSVRIPRLRERPEDIPWLVDAALRDAAAAGARAGMSAPPRAHASLIEACLLRAWPGNVRELTAEIRAAAQEAHLAGSSVVHERHLSPSAGQLAVRGTPPVVSGGATGRAAKDAERAPQPAAGERPSRRAASWPAEEEIEAALRREQGNVTRAARALGLHRNQLRRWLAQRAAGGGEDAEG
>NC_021658.1|WP_044989848.1|14277130_14278231_+|hypothetical-protein
MPSQTVRLVSYGRRAHGPSWRGSTVKHHLVVHEAGSGSVMFMTKDPREWKSALQELGKVCGAAWRDDLSEEEDRAWAEAHRKEFNRWVDGRAAPPWPMLIAAVKRAFVAGYRMLERKPTTEAEALARLDRTYLWKLLTAEDVAQGHGPEALRAFQRGFRLGRSERPFSTKRNIPRLVDPPYFWRGTLNSLDRPGPSAERNRTLLVQWHDSKGVEESTKIRQALHELYASAWREDVPEEDRAWAEAYRETCAYWVTVRRRDAVAQSAYEAYLGSSDGILDGEPAPPWSKQCHRDSEPWRFVADRVEDAPEGESELATAEAAAREFWDARWREAPPWDGDPAQAHWLAAVRAARITSAAMADHIPKPY
>NC_021658.1|WP_148314616.1|14276540_14277206_+|hypothetical-protein
MRRLCVAALVPLVVGCSIVDPEDREELRRQIASMPSSEANEYKRWYMKWRAQRWLAGKDPNDEVGKVQCRDNEGGLWSGWYDRPNKFLSVEDVVNCLVKKANSTYLFCAEEFASWVVPDAKKEIEKLLPAYTDIECKYVWDFRYEPEKVDPKMVDPDAITPDDLIEALITLPGPPPGWVLPRFAPLLCPLGAGPGWGCPPRPSDSFPTGGEPTDPPGGDQP
>NC_021658.1|WP_020742004.1|14275077_14276268_+|glycosyltransferase
MTGAPEVRPAGGEGPRAAPGQPAKVAHVVLSLNVGGLERVVLRLLERTARDRFAPIVCALEEPGALAEELARLGVPLVVLPRRPGLDPGLPVRLSAWLRREGIRLVHTHNPGPHLYGALAAGLARAASLPGRGGGPCVIHTKHGRNYPKQKRKVLVNRLAAALTDRVVAVSDDARAVALEVERVDPARVVTILNGVDTDVFRPGDAGAARARLGVPASGYHVGCVARLSPEKDHATLLAAFARLREVRPDAHLTLIGDGPLRPALEEQAARLGLGGAVTFTGTRGDVAELLPAFDVFALASLTEGISLTLIEAAAAGLPIVATRVGGNPEIIEEGSTGLLVSPGAPEPLAAALEAVAAREDRAAMGERGRARVIERFGLDQMVRAYEALYAEVLGG
>NC_021658.1|WP_044987177.1|14273710_14275081_+|phenylacetate--CoA-ligase-family-protein
MYSTLFRNVLFPVYETKLRRRATLTYLEELKRSQWRPESELRELNWRKMLATLRFAEQNVPFYRRRFAEYGVRVKDVHAPEDLVRFPVLTKADLRAHGDELIADGWNGKLFRSGTGGSTGEPARFFYDHTTYECRQAAALRADAWAGGRIGDKELYIWGIPTHEPRWKKVKRTLHEAFIRKKTVSAWNLSEARLAGVVDEILRYQPNLVVGYTSPLYYTARYALEAGCRLPTPKGIIATAERLFPHQREVIEKAFQAPVYDRYGCREMMLIGAECERREGKHLNIENIFVEVQCGDRLARPGEPGEVILTDLLCRSMPLIRYKNEDVVIAADKSCSCGRGLPLLASVEGRVLDMIVGPNGQLLSAVFFPYFFKDNPTVERYQVHQDKSRAITIRIVPGAGYQAETSQAIERDLRRFLGERADIRVELVDEIPVTSGGKFRFTVSEVPIEFGREAAA
>NC_021658.1|WP_148314615.1|14269439_14273399_+|protein-kinase
MILAVPMKPGDIVADRFLIERLAGSGGMGSVYRALDRHTGETAALKVMSGRGLEHSERFAREAQVLAELRHPGIVRYIAQGATESGEPWLALEWLEGESLADRLRRRGLTVAESVTLGLRVAEALAEAHRNNVVHRDLKPSNLYLVDKAVEHVKLLDFGIARLTSLAPLTMTGVVMGTPFYMAPEQARGERAVGTPADVFALGCVLFHCLTGRPPFVGDDIHTALLRVVLDEAPRLRDLRADIPESIDAAVAHMLAKDPAQRPANGAAVALELLRVGEIKSTPPAPVSRRASALTTGERRTVCLMLARVGQPEAPAWQGPTMPMTLPMTMPLARTVSEDEVKRVATRFGGTLQTLADGLLLITLEGRGLITDQAARAARCALEVRDLLPGVQMALVAGRGSADDRLPMGPTIDRAVRLLDRADGGSVRLDEVMAGLLDARFDVGGDATGLVLRAERDLVEAARTLLGRTTPFVGRDHELAILDAVLDECLAEPTARAVLITAPAGLGKSRLRYEFLRRVEEREQRVQVWLGHADPMSAGSPFGMLRQMLRREAGLSGGEPQEVREQRLRARVGRTLSGGDLARVTEFLGEVARIHFPDEGRVELRAARSDPMLMGDQIRRAWEDFVLAECRDEPVLLVLEDLQWGDVPTVKLIDAALALRDQPLMVLALARPEVEAVFPKVWVSRGVQEIRLREIGRRGSERLVREVLGDAVTPDLCARLCERAGGNAFYLEELIRAAASGRTEALPETVLSMVQARLESLDGEARRVLRAASVFGQKFWRGGLMALLGGERRAPQVDGWLAVLVDRELIARRGEGKFRGHDEYAFRHALVREAAYATLTDADRALGHLLAGEWLEAAGERDAALLADHFERGGDAERAVIWFRRAAEQALGANDFRAAIQRAEQGAASADVDGELFAALRLVQAEAHKWLGEAAEAERCAVMAMNGFPRKSALWYAAAAEAASMRVRLGMGERLADLVDELRGGRPSGERGGPPELLDEATGASVSALARIAGSLLHGGQYAAAEEIVQELARVAMPLAERDAAVAARLHALRASQALCYGDPAASLEWTEQSIPAYLQTGDIRNACLSRVNAAHCLVQLGAYGRAEAELRDALAEAERMGLYNVAAFAKQNLGLLWIQQGDLGAARAVTAEAVEAFAAQANRRQEARSRAYLAAILTRLGSLGAADNEAGAAVAMLAHVPTLQALALAVRARVLLEQGRAHEALEAARRGLGLLVSVGGTEEGEAQIRLVYAESLRAAGHHDAAREAIAVAMQRLVARAQWIRDPARRQSFCQAVPENAKTFALAALWQQEAEPTLQ
>NC_021658.1|WP_020742000.1|14267729_14268842_-|AAA-family-ATPase
MKISRATIENFKKFAPPGVELDFKNKATGDVADRYLILGDNASGKTTILQAIALTLSLAQRKIPDIRHFGWTGWAPERYFVHGDPIVELTVEFEDDEIAATQEAARRWWDLVSPTSHESFREPGDSRVVTLRLEGARVRTTGSAREIYQFRGRSYVAASVRNDAKVRALFSRLPGVFWYDQFRNIALSGARELSEREASDPAPPNETGVRFETAVARLDTILKIWHRNRERLGPHPERDYLGELESLCRTAFPGRSFAGLETLFDGPTPADDRFVLKDGGRTYTLSEMSAGEQSVFPVLFEVVRQQIHRSVVLIDEIDLNLHPPLAQTLLGLLPRLGEDNQFLFTTHARAVSTLVSPHTIHRLPEGRPCL
>NC_021658.1|WP_020741999.1|14267154_14267733_-|hypothetical-protein
MSVLLCEGEDNGPDVRLLHAILRGTGVQVSRYVAQLERVFDALGHVTAARIALTCCAPRRNRLETQVRLDATKQELAQELQDKADAYTEGTRLDKDKLLQAFERHVPDCLSGGRFRQHALEVFAGKNILAKIQHTPGFHPILKRKPELEERILNALEHDAEPHSWLPEWAALRSAVEAWMPAPETEATSAGA
>NC_021658.1|WP_044987175.1|14266029_14267112_-|histidinol-phosphate-transaminase
MSALVLPTVEMLAPYEAGKPIEELARELGVTDAVKLASNENPLGPSPRAVEAARRELATMNFYPDASAYRLRERLAAVHGVAMEEIVQGNGSNELLDLMVHTFATPGSHIVFGDPAFVVYKLAALAYGVPFTAVPLRDLRHDLEAMAAAVTPKTRLLFVANPNNPTGTHVGRGAVERLLKEVPPEVVIVMDEAYLEYTDAPDYPDSMRLRHLRERLLVVRTFSKIYGLAGLRVGYAVGPAKLIDYMNRTRAPFNVGAIAQAAAIAALDDAEHVEKSRALNLRERDRLTRELTRLGLSVAPSQANFVLVDVRRPARPVYDALLRKGVIVRPFGNLPTSLRVTIGTERENQRFLDSLADALK
>NC_021658.1|WP_148315079.1|14265189_14265972_+|hypothetical-protein
MEESMSEQTSIKVVVPREMTPDEKQILVDELYALRRKIFEGAQRKRSFASHVVEAGAERGAVVLHRGAGGRLVGYFAMEILERESSGATVAIFRGESGALGGRSGGDGALRLVGDVVLRLVLERLIRYMLAHPGRPVHCLCSLAHPSSYALFSRFVDITHTGPVEGQAAGADALMAGLAASFDLRSSEHGSPLVFEAGRADEPTDDCGFLHLYENPSVRCFVSAHPGTAEGRGLVTLVPLSLGGMVRAASRYAGPVSRRG
>NC_021658.1|WP_148314618.1|14282822_14285882_+|protein-kinase
MSPASGISSVPVIDARGSCSDDEEAVTPPPGRRGRPQARQGVGLSTTLITEAPPHTAPAADDAPTDERAAATSAPSRRAPQEPPVAAGAFLGHYELIRELGRGGMGTVFLARDVRLGRLVAIKLVTTLTGSRLDRFLVEARATALCKHENIVTIYDVNEHDGYPYMVLEYIEGQSLRAWMMQRRPAGAARGAAATPLSTSAAVEMMVPVVRALACAHKLGIVHRDLKPENIMLEASGAIKVLDFGIAKLLDGRAAAARDEHAPPGPTELTGALPLTRDGAVMGTLAYMSPEQRAGEEIDHATDIWAVGIMLHELVTGAHPFEEAGAPGSARPAALDAPVRALGGARGDLGPLGPIIERCLRRQRSERFASAQQLLAELTPLLPGRREIVLGAAESPFAGLSAFQEVDADRFFGREDDIAGMVARLKSQPLLAVVGASGVGKSSLVRAGIIPALKRSGAGWASLVMRPGREPMAALADLLGHPALREETEAKTEDDAPAELARDSARGQRIERLRAEPGYLGAALRAWSARHQRRVVLFVDQFEELYTLSCDARDRAAFFSCLEGVADDASSPLRVILSTRSDFIERVAEDRRFMAGVTRGLVFLSPIGREGLRDALVKPIQAARYEIEDPAMVDGILDALETTHGALPLLQFTAARLWDMRDRDRRLLTRASYEAIGGVAGTLASHADAVLAGLGGRQAKLCRAILERLVTPERTRAIASLEELRELPGDGDPDELESVVHLLADARLLAIETGRDDAGSKVEIVHESLIARWPTLLRWLDENQEDAVFLGKLRAAARHWASSGGADDLLWRGKLAEEARRFRERSERRLPEREQRYLDAVIGLAGQAQRRKRNLIVGTIASLALLVVGATAGIVTVVRQNRVISAQLADIRRTEDSLEEALARETASRQAAEQARMSTEEQRKRAELLQKEAEEARDRAEAEAERARAAAGEARTARDEARTSEAEARRAEAQADDERARAGVEARKAKQAADDERRSKEELEQLIQRSVGRIRDRLR
>NC_021658.1|WP_187346074.1|14285966_14286920_+|hypothetical-protein
MAIVASRAAPAWAQAEAALPPWHEGVPEARKQAALELFMQGRDLHRRMVLGDAKKKYEEALALWEHPDLRFYLGRVLKMMGMPLLAYENLRLSLRWGPASLDPEDHEEARALMKELVERELAVVEVRCDEPGAAVLLDGRPWFVGPGSARRFVTPGEHVISARKEGYFPLVEPVVVLAGAQASGALTLSVDGIVTVRRWAAWKPWAVVGAGAGLGLAGAVLRWKADEHLEAAEQRFEETCTSNCAPTTTDTTSRGLTESRVATGLFIAGGATLAAGAVLVFLNLPRTYRSEDRGGVELRIVPAATGAIAGLSARLSF
>NC_021658.1|WP_044987179.1|14286954_14288136_-|hypothetical-protein
MRYRDERDALRGRVDSLEEQLASAKKELEDQRDEGRAARVEQLERQMDEARRVLDQLGRELDDLRGRPRRSLIVPILATIAGVGFCAMVAGYAMMRPESYAINGPPRPIAAPPPEPAPVSPPPAPPPREPAAPAPEKPLGTRTATWKATVARSTGLPLSAGAPCTVEARLTSSGDDLRVPALDVVCGGRAIYRSSDPLNGMSMFRSGVEEDRGAAPDTYVYALSYDDKGTRAGERAEVSLDSLGRTGAVWRDSAPAYRVELTLSPQSAPVGGEPLLDATGKALRRSARVAEATGPSPVKAGAKCALRSSWIPRSDKCRTRIECGGRMLYGAGTTGMSGCAVEEGRVVRVHDGNTTQNGGDPALDLDVAAGRATLRDEGKGGAWTVGITLDPSE
>NC_021658.1|WP_044987181.1|14288393_14290631_+|substrate-binding-domain-containing-protein
MGQGRQRSGVPLPEQWGDLPGTASRQARVTAGAAAGRADVPRGAASPRTIGVVAPFLSGAFWGPVLIGIHEAAQRRGHRTLVLRGTPSEVQAPSLGGEQVDGWIVIIEFDGLAELARAGVPFITLGARPADIVCPAVLPDNHGGVRSAVLHLIEHGHRRIAFVGNFAAYDVRERRDAYKDALVEAGIPVDPDLIIPCDNNMYSGGRAVAPELLARLPGCTAAVFGTDKNALGMMSALKAAGVRLPEDFAIIGFDDVAEAQSADPPLSTVRQRFEMMGSAACELILTMIAGETFPAEGVRTANALIQRSSCGCNVIQNFLDARDEAPEEDAADAVARRMVELLILPRPLPPDTPPTDVWPAVTRVVDMYFSVLRGAAPAPAAELERAYRQAVDITPDLGALLATARLLGQLPERRRAPLDAAARRRVDDFLELARLAIARARLAAETQNVHQLGVLARTNYEVSFALLGGTQQEYRSLSWLETTTVVWGCLALWDDPAARAELVIAGAYSRDGGPVPPDGSRCRLEAFPPETMLPPSATDGTYSVFLLPIRSAQRDWGILALVGPTIVAMTGDEGTVAIWGTLLGAALERDALVASLSAQHADLQKAYAIERALSETVRELGWALIPLLPGVLLVPLIGMIDGGRAQQVLEKVAEGVSRHEALRVLLDLTGVPFVDAQVAHSLGMTSRAAAMLGARVYLVGVRPDIARSLADVDLGALATFSSLSAALRELAPAGGRSLKGRRGAR
>NC_021658.1|WP_044989854.1|14290978_14292013_+|hypothetical-protein
MPDGRVIIGFHPFYEPEVQVALLNADRESTTPYPSAAWQSCKNADGSWKSDFNACLDWVLGLHTDQNGVLWLLDSAKSTDKAAGRPAGLVPKLVGWNTHQNKLERVIPISPEATLTESQHNDFVVDLKHDVIVIADEAIGEGSGGAGDKAALVVVDLSTGGSRRLLQGHPSVMPLKEPIRWDVGRPTSGAVDLYVGVDGIALDTKSEWLYFAPLNAYKMYRIRMSDLLDTSLTAAQLGAKVETYADKPFNGGLAIDRDDNLYLTEVGERAVGVIPSSTRKYERLVSDPDLVWPDGVTYNSDGSMYTGAAQLSLTSALQADGVARNERPYLVYRFKPLAPGTPGF
>NC_021658.1|WP_020742012.1|14291970_14292912_-|LysR-family-transcriptional-regulator
MSIESIEDLRVLVETARRGTLTAAARVLGVTPAAASAMLKRLEAQLGERLFERSTRALRLTPEGQILLDYASRALDLLEEGEAQLASQRRSLVGTVRVAAPSDLARSVLLPWLDEFVAAHPGVRLALSVTDRVQDVMRDVVDLALRYGELSDSRLVARALSTTRRVLCASPAYLARREPPRSPDDLAQHNCLTFHVNHKRHVAWRFEKDGAWTEVRVDGDRDADDAAIAHHWALAGAGLLYKSELDLVHDLREGRLVRLLPGWQGEPYPLNAILPSHRFVPARVRALVDFLAAKLRDLSPQKPGVPGARGLKR
>NC_021658.1|WP_187345819.1|14293934_14294684_-|SDR-family-oxidoreductase
MLSNKVVLITGATSGIGAATAIAAARAGAKVVLAARRQEMGDALVARIKVEGGNALFVRTDVTVEADIQALIERTVEAHGRLDSVFNNAGIATALGPLADVPVADYLALMQVNLHSIYLCMRYQVPVMKKGGGGSIVNCGSIASTVSAPGFGVYAATKHAILGLTKSAAIDYAADKIRVNAILPGPVETEIWDHMQSGEQVLDAFGAATLMKRYAHADEIARPAVFLLSDWSSYMTGTQLTVDGGYTAV
>NC_021658.1|WP_148314619.1|14296306_14296879_+|transposase
MLTFPFSWWRRLAQDGASFGVLTRIFVESVERFYETRAARRGACGAVKSGAVTDVQRTSGDMRLNPHLHVVFLDGAYHEDGTELVWNELGDLRTGEVGQVLEHAVGRMLRTLRRHGHLEIEHDVEEDDEPEAVLCASAVSGREPRHTSSPRNGSAGSRRLLRARSRTTSRCALRSMASPCTQRRAPVRTI
>NC_021658.1|WP_044987183.1|14297017_14297959_-|MBL-fold-metallo-hydrolase
MLRAASSTALMALLAASALSCNSMPGRVLSGNTGALFGGPAPVANKVREPYRKDARLAVLWVGHATALVQIDDKQILTDPVFTSTVGLLAARLVEPGLDPEHVPPLSAVLVSHTHFDHLSLGSLEMIEEKTPVLFVPRGALPYVPDFAFDTIELSTWQRWEHDGLRITAVPVKHGGGRYGVDIALGWGGFTGYVVEYHGITVYFGGDTAYDRKVFTETRARFPAIDLALMPIAPMGPRDFMHSRHVDPAEALEACEELGAKWMVPIHFDTFINSSDEPGQAASELKRVMAARRIAPGKVHILAPGEQRILLGR
>NC_021658.1|WP_063752111.1|14297963_14298698_-|hypothetical-protein
MARASCHRAEENATAPASGNVAPSPSSRCSASACARLRAAAGARLPCIARGGPATALRRSLAGAALAGALAWGSPARAAETQSLAEAGISPDLAWAASQLIPSPTWHLYADDTRFGLRWQLTPLLYSFGRNRRLSPWRSLLAEPLARHAGALEIHVTPEYLFSGAGIEDHVQLTGGVRAYFPLLHRGEYLSCSLGGSAFTLGGEVAAAYEAGLYTLFGVIGVQVAYSPTRALRGTTLTLNLRYF

Crispr_ID: NC_021658_63

• CRISPR_ID: NC_021658_63
• CRISPR_location: 14281905-14282075
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_021658_63

Consensus_repeat	Method
CGAGCATCGCGCATTACGACGGCAGCTCCTGGACAT	PILER-CR

spacers of NC_021658_63

>63.1|14281941|41|NC_021658|PILER-CR
CCATGAATGACCCGCTGGGCGGGCGTCTCTTCGACGTGTGG
>63.2|14282018|52|NC_021658|PILER-CR
GGCCCGAACGACGTCTTCGTCGTCGGAGACACGGGCGTCGTTCACGGAGATA

CRISPR arrays and Neighbor proteins around NC_021658_63

CRISPR arrays

The CRISPR arrays of NC_021658_63

>merge|NC_021658|63|14281905-14282075|PILER-CR
CGAGCATCGTGCATTATGACGGCAGCTCCTGGACATCCATGAATGACCCGCTGGGCGGGCGTCTCTTCGACGTGTGGGGCAGCGGCCCGAACGACGTCTTCGTCGTCGGAGACACGGGCGTCGTTCACGGAGATACGGGCATCGCGCATTACGACGGCAGCTCCTGGACAT

>NC_021658|63|6|14281905-14282075|PILER-CR
CGAGCATCGTGCATTATGACGGCAGCTCCTGGACAT	CCATGAATGACCCGCTGGGCGGGCGTCTCTTCGACGTGTGG
GGCAGCGGCCCGAACGACGTCTTCGTCGTCGGAGAC	ACGGGCGTCGTTCACGGAGATACGGGCATCGCGCATTACGACGGCAGCTCCT
GGACAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_187346074.1|14285966_14286920_+|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NC_021658.1|WP_148314618.1|14282822_14285882_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_063752111.1|14297963_14298698_-|hypothetical-protein	unknown	unknown	gnl|CDD|177676
NC_021658.1|WP_148314616.1|14276540_14277206_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044987177.1|14273710_14275081_+|phenylacetate--CoA-ligase-family-protein	unknown	unknown	gnl|CDD|224458
NC_021658.1|WP_044989854.1|14290978_14292013_+|hypothetical-protein	unknown	unknown	gnl|CDD|308585
NC_021658.1|WP_044987175.1|14266029_14267112_-|histidinol-phosphate-transaminase	unknown	unknown	gnl|CDD|235064
NC_021658.1|WP_020741999.1|14267154_14267733_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314619.1|14296306_14296879_+|transposase	unknown	unknown	unknown
NC_021658.1|WP_020742000.1|14267729_14268842_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379114
NC_021658.1|WP_148314615.1|14269439_14273399_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_044987179.1|14286954_14288136_-|hypothetical-protein	unknown	unknown	gnl|CDD|275056
NC_021658.1|WP_020742004.1|14275077_14276268_+|glycosyltransferase	unknown	unknown	gnl|CDD|340836
NC_021658.1|WP_020742012.1|14291970_14292912_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176114
NC_021658.1|WP_044987183.1|14297017_14297959_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293841
NC_021658.1|WP_187345819.1|14293934_14294684_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|180440
NC_021658.1|WP_044989848.1|14277130_14278231_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_044987181.1|14288393_14290631_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380491
NC_021658.1|WP_148315080.1|14278422_14279775_-|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl|CDD|225114
NC_021658.1|WP_148315079.1|14265189_14265972_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_187346074.1|14285966_14286920_+|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00608484
NC_021658.1|WP_148314618.1|14282822_14285882_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	7.17453e-83
NC_021658.1|WP_063752111.1|14297963_14298698_-|hypothetical-protein	gnl|CDD|177676	PLN00042, PLN00042, photosystem II oxygen-evolving enhancer protein 2; Provisional.	0.00208189
NC_021658.1|WP_044987177.1|14273710_14275081_+|phenylacetate--CoA-ligase-family-protein	gnl|CDD|224458	COG1541, PaaK, Coenzyme F390 synthetase [Coenzyme metabolism].	6.20439e-59
NC_021658.1|WP_044989854.1|14290978_14292013_+|hypothetical-protein	gnl|CDD|308585	pfam03022, MRJP, Major royal jelly protein. Royal jelly is the food of queen bee larvae, and is responsible for the high reproductive ability of the queen. Major royal jelly proteins make up around 90% of larval jelly proteins. This family also the sequence-related yellow protein of drosophila which controls pigmentation of the adult cuticle and larval mouth parts.	7.06453e-14
NC_021658.1|WP_044987175.1|14266029_14267112_-|histidinol-phosphate-transaminase	gnl|CDD|235064	PRK02731, PRK02731, histidinol-phosphate aminotransferase; Validated.	0
NC_021658.1|WP_020742000.1|14267729_14268842_-|AAA-family-ATPase	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	9.77281e-15
NC_021658.1|WP_148314615.1|14269439_14273399_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.59266e-86
NC_021658.1|WP_148315080.1|14278422_14279775_-|sigma-54-interacting-transcriptional-regulator	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	8.81688e-79
NC_021658.1|WP_020742004.1|14275077_14276268_+|glycosyltransferase	gnl|CDD|340836	cd03807, GT4_WbnK-like, Shigella dysenteriae WbnK and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.	7.45347e-123
NC_021658.1|WP_020742012.1|14291970_14292912_-|LysR-family-transcriptional-regulator	gnl|CDD|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.51972e-75
NC_021658.1|WP_044987183.1|14297017_14297959_-|MBL-fold-metallo-hydrolase	gnl|CDD|293841	cd16283, RomA-like_MBL-fold, Enterobacter cloacae RomA and related proteins; MBL-fold metallo hydrolase domain. Derepression of the romA-ramA locus results in a multidrug-resistance phenotype. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	7.68517e-42
NC_021658.1|WP_044987181.1|14288393_14290631_+|substrate-binding-domain-containing-protein	gnl|CDD|380491	cd06267, PBP1_LacI_sugar_binding-like, ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. Ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. In most cases, ligands are monosaccharide including lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. The LacI family of proteins consists of transcriptional regulators related to the lac repressor. In this case, the domain sugar binding changes the DNA binding activity of the repressor domain.	1.1128e-66
NC_021658.1|WP_044987179.1|14286954_14288136_-|hypothetical-protein	gnl|CDD|275056	TIGR04211, hypothetical_protein, SH3 domain protein. Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.	0.000390931
NC_021658.1|WP_187345819.1|14293934_14294684_-|SDR-family-oxidoreductase	gnl|CDD|180440	PRK06172, PRK06172, SDR family oxidoreductase.	2.80986e-84

Protein sequences

>NC_021658.1|WP_148315080.1|14278422_14279775_-|sigma-54-interacting-transcriptional-regulator
MLIFSADSPRCDVLPLEDGEIELGRCEVAGVHLDDQRMSRRHARVRWLGGTWQVEDLDSRNGTWLDGVPLTGARAGADFRIVRTGWSVFLLLADVEPFRAGVSRAGGTIRGATLARTWDAIDRAARLGTTLHIAGESGTGKEHAARAFHALGRRRDGPFVPVNCAAIPAGLAERLLFGARKGAYSGAASDADGYLQAAHGGVLFLDEVAELDLGVQAKLLRALEAKEVLPLGASRPAQVDFALVSATHKDLRAQMAAGMLRDDLYFRIGRPSVRIPRLRERPEDIPWLVDAALRDAAAAGARAGMSAPPRAHASLIEACLLRAWPGNVRELTAEIRAAAQEAHLAGSSVVHERHLSPSAGQLAVRGTPPVVSGGATGRAAKDAERAPQPAAGERPSRRAASWPAEEEIEAALRREQGNVTRAARALGLHRNQLRRWLAQRAAGGGEDAEG
>NC_021658.1|WP_044989848.1|14277130_14278231_+|hypothetical-protein
MPSQTVRLVSYGRRAHGPSWRGSTVKHHLVVHEAGSGSVMFMTKDPREWKSALQELGKVCGAAWRDDLSEEEDRAWAEAHRKEFNRWVDGRAAPPWPMLIAAVKRAFVAGYRMLERKPTTEAEALARLDRTYLWKLLTAEDVAQGHGPEALRAFQRGFRLGRSERPFSTKRNIPRLVDPPYFWRGTLNSLDRPGPSAERNRTLLVQWHDSKGVEESTKIRQALHELYASAWREDVPEEDRAWAEAYRETCAYWVTVRRRDAVAQSAYEAYLGSSDGILDGEPAPPWSKQCHRDSEPWRFVADRVEDAPEGESELATAEAAAREFWDARWREAPPWDGDPAQAHWLAAVRAARITSAAMADHIPKPY
>NC_021658.1|WP_148314616.1|14276540_14277206_+|hypothetical-protein
MRRLCVAALVPLVVGCSIVDPEDREELRRQIASMPSSEANEYKRWYMKWRAQRWLAGKDPNDEVGKVQCRDNEGGLWSGWYDRPNKFLSVEDVVNCLVKKANSTYLFCAEEFASWVVPDAKKEIEKLLPAYTDIECKYVWDFRYEPEKVDPKMVDPDAITPDDLIEALITLPGPPPGWVLPRFAPLLCPLGAGPGWGCPPRPSDSFPTGGEPTDPPGGDQP
>NC_021658.1|WP_020742004.1|14275077_14276268_+|glycosyltransferase
MTGAPEVRPAGGEGPRAAPGQPAKVAHVVLSLNVGGLERVVLRLLERTARDRFAPIVCALEEPGALAEELARLGVPLVVLPRRPGLDPGLPVRLSAWLRREGIRLVHTHNPGPHLYGALAAGLARAASLPGRGGGPCVIHTKHGRNYPKQKRKVLVNRLAAALTDRVVAVSDDARAVALEVERVDPARVVTILNGVDTDVFRPGDAGAARARLGVPASGYHVGCVARLSPEKDHATLLAAFARLREVRPDAHLTLIGDGPLRPALEEQAARLGLGGAVTFTGTRGDVAELLPAFDVFALASLTEGISLTLIEAAAAGLPIVATRVGGNPEIIEEGSTGLLVSPGAPEPLAAALEAVAAREDRAAMGERGRARVIERFGLDQMVRAYEALYAEVLGG
>NC_021658.1|WP_044987177.1|14273710_14275081_+|phenylacetate--CoA-ligase-family-protein
MYSTLFRNVLFPVYETKLRRRATLTYLEELKRSQWRPESELRELNWRKMLATLRFAEQNVPFYRRRFAEYGVRVKDVHAPEDLVRFPVLTKADLRAHGDELIADGWNGKLFRSGTGGSTGEPARFFYDHTTYECRQAAALRADAWAGGRIGDKELYIWGIPTHEPRWKKVKRTLHEAFIRKKTVSAWNLSEARLAGVVDEILRYQPNLVVGYTSPLYYTARYALEAGCRLPTPKGIIATAERLFPHQREVIEKAFQAPVYDRYGCREMMLIGAECERREGKHLNIENIFVEVQCGDRLARPGEPGEVILTDLLCRSMPLIRYKNEDVVIAADKSCSCGRGLPLLASVEGRVLDMIVGPNGQLLSAVFFPYFFKDNPTVERYQVHQDKSRAITIRIVPGAGYQAETSQAIERDLRRFLGERADIRVELVDEIPVTSGGKFRFTVSEVPIEFGREAAA
>NC_021658.1|WP_148314615.1|14269439_14273399_+|protein-kinase
MILAVPMKPGDIVADRFLIERLAGSGGMGSVYRALDRHTGETAALKVMSGRGLEHSERFAREAQVLAELRHPGIVRYIAQGATESGEPWLALEWLEGESLADRLRRRGLTVAESVTLGLRVAEALAEAHRNNVVHRDLKPSNLYLVDKAVEHVKLLDFGIARLTSLAPLTMTGVVMGTPFYMAPEQARGERAVGTPADVFALGCVLFHCLTGRPPFVGDDIHTALLRVVLDEAPRLRDLRADIPESIDAAVAHMLAKDPAQRPANGAAVALELLRVGEIKSTPPAPVSRRASALTTGERRTVCLMLARVGQPEAPAWQGPTMPMTLPMTMPLARTVSEDEVKRVATRFGGTLQTLADGLLLITLEGRGLITDQAARAARCALEVRDLLPGVQMALVAGRGSADDRLPMGPTIDRAVRLLDRADGGSVRLDEVMAGLLDARFDVGGDATGLVLRAERDLVEAARTLLGRTTPFVGRDHELAILDAVLDECLAEPTARAVLITAPAGLGKSRLRYEFLRRVEEREQRVQVWLGHADPMSAGSPFGMLRQMLRREAGLSGGEPQEVREQRLRARVGRTLSGGDLARVTEFLGEVARIHFPDEGRVELRAARSDPMLMGDQIRRAWEDFVLAECRDEPVLLVLEDLQWGDVPTVKLIDAALALRDQPLMVLALARPEVEAVFPKVWVSRGVQEIRLREIGRRGSERLVREVLGDAVTPDLCARLCERAGGNAFYLEELIRAAASGRTEALPETVLSMVQARLESLDGEARRVLRAASVFGQKFWRGGLMALLGGERRAPQVDGWLAVLVDRELIARRGEGKFRGHDEYAFRHALVREAAYATLTDADRALGHLLAGEWLEAAGERDAALLADHFERGGDAERAVIWFRRAAEQALGANDFRAAIQRAEQGAASADVDGELFAALRLVQAEAHKWLGEAAEAERCAVMAMNGFPRKSALWYAAAAEAASMRVRLGMGERLADLVDELRGGRPSGERGGPPELLDEATGASVSALARIAGSLLHGGQYAAAEEIVQELARVAMPLAERDAAVAARLHALRASQALCYGDPAASLEWTEQSIPAYLQTGDIRNACLSRVNAAHCLVQLGAYGRAEAELRDALAEAERMGLYNVAAFAKQNLGLLWIQQGDLGAARAVTAEAVEAFAAQANRRQEARSRAYLAAILTRLGSLGAADNEAGAAVAMLAHVPTLQALALAVRARVLLEQGRAHEALEAARRGLGLLVSVGGTEEGEAQIRLVYAESLRAAGHHDAAREAIAVAMQRLVARAQWIRDPARRQSFCQAVPENAKTFALAALWQQEAEPTLQ
>NC_021658.1|WP_020742000.1|14267729_14268842_-|AAA-family-ATPase
MKISRATIENFKKFAPPGVELDFKNKATGDVADRYLILGDNASGKTTILQAIALTLSLAQRKIPDIRHFGWTGWAPERYFVHGDPIVELTVEFEDDEIAATQEAARRWWDLVSPTSHESFREPGDSRVVTLRLEGARVRTTGSAREIYQFRGRSYVAASVRNDAKVRALFSRLPGVFWYDQFRNIALSGARELSEREASDPAPPNETGVRFETAVARLDTILKIWHRNRERLGPHPERDYLGELESLCRTAFPGRSFAGLETLFDGPTPADDRFVLKDGGRTYTLSEMSAGEQSVFPVLFEVVRQQIHRSVVLIDEIDLNLHPPLAQTLLGLLPRLGEDNQFLFTTHARAVSTLVSPHTIHRLPEGRPCL
>NC_021658.1|WP_020741999.1|14267154_14267733_-|hypothetical-protein
MSVLLCEGEDNGPDVRLLHAILRGTGVQVSRYVAQLERVFDALGHVTAARIALTCCAPRRNRLETQVRLDATKQELAQELQDKADAYTEGTRLDKDKLLQAFERHVPDCLSGGRFRQHALEVFAGKNILAKIQHTPGFHPILKRKPELEERILNALEHDAEPHSWLPEWAALRSAVEAWMPAPETEATSAGA
>NC_021658.1|WP_044987175.1|14266029_14267112_-|histidinol-phosphate-transaminase
MSALVLPTVEMLAPYEAGKPIEELARELGVTDAVKLASNENPLGPSPRAVEAARRELATMNFYPDASAYRLRERLAAVHGVAMEEIVQGNGSNELLDLMVHTFATPGSHIVFGDPAFVVYKLAALAYGVPFTAVPLRDLRHDLEAMAAAVTPKTRLLFVANPNNPTGTHVGRGAVERLLKEVPPEVVIVMDEAYLEYTDAPDYPDSMRLRHLRERLLVVRTFSKIYGLAGLRVGYAVGPAKLIDYMNRTRAPFNVGAIAQAAAIAALDDAEHVEKSRALNLRERDRLTRELTRLGLSVAPSQANFVLVDVRRPARPVYDALLRKGVIVRPFGNLPTSLRVTIGTERENQRFLDSLADALK
>NC_021658.1|WP_148315079.1|14265189_14265972_+|hypothetical-protein
MEESMSEQTSIKVVVPREMTPDEKQILVDELYALRRKIFEGAQRKRSFASHVVEAGAERGAVVLHRGAGGRLVGYFAMEILERESSGATVAIFRGESGALGGRSGGDGALRLVGDVVLRLVLERLIRYMLAHPGRPVHCLCSLAHPSSYALFSRFVDITHTGPVEGQAAGADALMAGLAASFDLRSSEHGSPLVFEAGRADEPTDDCGFLHLYENPSVRCFVSAHPGTAEGRGLVTLVPLSLGGMVRAASRYAGPVSRRG
>NC_021658.1|WP_148314618.1|14282822_14285882_+|protein-kinase
MSPASGISSVPVIDARGSCSDDEEAVTPPPGRRGRPQARQGVGLSTTLITEAPPHTAPAADDAPTDERAAATSAPSRRAPQEPPVAAGAFLGHYELIRELGRGGMGTVFLARDVRLGRLVAIKLVTTLTGSRLDRFLVEARATALCKHENIVTIYDVNEHDGYPYMVLEYIEGQSLRAWMMQRRPAGAARGAAATPLSTSAAVEMMVPVVRALACAHKLGIVHRDLKPENIMLEASGAIKVLDFGIAKLLDGRAAAARDEHAPPGPTELTGALPLTRDGAVMGTLAYMSPEQRAGEEIDHATDIWAVGIMLHELVTGAHPFEEAGAPGSARPAALDAPVRALGGARGDLGPLGPIIERCLRRQRSERFASAQQLLAELTPLLPGRREIVLGAAESPFAGLSAFQEVDADRFFGREDDIAGMVARLKSQPLLAVVGASGVGKSSLVRAGIIPALKRSGAGWASLVMRPGREPMAALADLLGHPALREETEAKTEDDAPAELARDSARGQRIERLRAEPGYLGAALRAWSARHQRRVVLFVDQFEELYTLSCDARDRAAFFSCLEGVADDASSPLRVILSTRSDFIERVAEDRRFMAGVTRGLVFLSPIGREGLRDALVKPIQAARYEIEDPAMVDGILDALETTHGALPLLQFTAARLWDMRDRDRRLLTRASYEAIGGVAGTLASHADAVLAGLGGRQAKLCRAILERLVTPERTRAIASLEELRELPGDGDPDELESVVHLLADARLLAIETGRDDAGSKVEIVHESLIARWPTLLRWLDENQEDAVFLGKLRAAARHWASSGGADDLLWRGKLAEEARRFRERSERRLPEREQRYLDAVIGLAGQAQRRKRNLIVGTIASLALLVVGATAGIVTVVRQNRVISAQLADIRRTEDSLEEALARETASRQAAEQARMSTEEQRKRAELLQKEAEEARDRAEAEAERARAAAGEARTARDEARTSEAEARRAEAQADDERARAGVEARKAKQAADDERRSKEELEQLIQRSVGRIRDRLR
>NC_021658.1|WP_187346074.1|14285966_14286920_+|hypothetical-protein
MAIVASRAAPAWAQAEAALPPWHEGVPEARKQAALELFMQGRDLHRRMVLGDAKKKYEEALALWEHPDLRFYLGRVLKMMGMPLLAYENLRLSLRWGPASLDPEDHEEARALMKELVERELAVVEVRCDEPGAAVLLDGRPWFVGPGSARRFVTPGEHVISARKEGYFPLVEPVVVLAGAQASGALTLSVDGIVTVRRWAAWKPWAVVGAGAGLGLAGAVLRWKADEHLEAAEQRFEETCTSNCAPTTTDTTSRGLTESRVATGLFIAGGATLAAGAVLVFLNLPRTYRSEDRGGVELRIVPAATGAIAGLSARLSF
>NC_021658.1|WP_044987179.1|14286954_14288136_-|hypothetical-protein
MRYRDERDALRGRVDSLEEQLASAKKELEDQRDEGRAARVEQLERQMDEARRVLDQLGRELDDLRGRPRRSLIVPILATIAGVGFCAMVAGYAMMRPESYAINGPPRPIAAPPPEPAPVSPPPAPPPREPAAPAPEKPLGTRTATWKATVARSTGLPLSAGAPCTVEARLTSSGDDLRVPALDVVCGGRAIYRSSDPLNGMSMFRSGVEEDRGAAPDTYVYALSYDDKGTRAGERAEVSLDSLGRTGAVWRDSAPAYRVELTLSPQSAPVGGEPLLDATGKALRRSARVAEATGPSPVKAGAKCALRSSWIPRSDKCRTRIECGGRMLYGAGTTGMSGCAVEEGRVVRVHDGNTTQNGGDPALDLDVAAGRATLRDEGKGGAWTVGITLDPSE
>NC_021658.1|WP_044987181.1|14288393_14290631_+|substrate-binding-domain-containing-protein
MGQGRQRSGVPLPEQWGDLPGTASRQARVTAGAAAGRADVPRGAASPRTIGVVAPFLSGAFWGPVLIGIHEAAQRRGHRTLVLRGTPSEVQAPSLGGEQVDGWIVIIEFDGLAELARAGVPFITLGARPADIVCPAVLPDNHGGVRSAVLHLIEHGHRRIAFVGNFAAYDVRERRDAYKDALVEAGIPVDPDLIIPCDNNMYSGGRAVAPELLARLPGCTAAVFGTDKNALGMMSALKAAGVRLPEDFAIIGFDDVAEAQSADPPLSTVRQRFEMMGSAACELILTMIAGETFPAEGVRTANALIQRSSCGCNVIQNFLDARDEAPEEDAADAVARRMVELLILPRPLPPDTPPTDVWPAVTRVVDMYFSVLRGAAPAPAAELERAYRQAVDITPDLGALLATARLLGQLPERRRAPLDAAARRRVDDFLELARLAIARARLAAETQNVHQLGVLARTNYEVSFALLGGTQQEYRSLSWLETTTVVWGCLALWDDPAARAELVIAGAYSRDGGPVPPDGSRCRLEAFPPETMLPPSATDGTYSVFLLPIRSAQRDWGILALVGPTIVAMTGDEGTVAIWGTLLGAALERDALVASLSAQHADLQKAYAIERALSETVRELGWALIPLLPGVLLVPLIGMIDGGRAQQVLEKVAEGVSRHEALRVLLDLTGVPFVDAQVAHSLGMTSRAAAMLGARVYLVGVRPDIARSLADVDLGALATFSSLSAALRELAPAGGRSLKGRRGAR
>NC_021658.1|WP_044989854.1|14290978_14292013_+|hypothetical-protein
MPDGRVIIGFHPFYEPEVQVALLNADRESTTPYPSAAWQSCKNADGSWKSDFNACLDWVLGLHTDQNGVLWLLDSAKSTDKAAGRPAGLVPKLVGWNTHQNKLERVIPISPEATLTESQHNDFVVDLKHDVIVIADEAIGEGSGGAGDKAALVVVDLSTGGSRRLLQGHPSVMPLKEPIRWDVGRPTSGAVDLYVGVDGIALDTKSEWLYFAPLNAYKMYRIRMSDLLDTSLTAAQLGAKVETYADKPFNGGLAIDRDDNLYLTEVGERAVGVIPSSTRKYERLVSDPDLVWPDGVTYNSDGSMYTGAAQLSLTSALQADGVARNERPYLVYRFKPLAPGTPGF
>NC_021658.1|WP_020742012.1|14291970_14292912_-|LysR-family-transcriptional-regulator
MSIESIEDLRVLVETARRGTLTAAARVLGVTPAAASAMLKRLEAQLGERLFERSTRALRLTPEGQILLDYASRALDLLEEGEAQLASQRRSLVGTVRVAAPSDLARSVLLPWLDEFVAAHPGVRLALSVTDRVQDVMRDVVDLALRYGELSDSRLVARALSTTRRVLCASPAYLARREPPRSPDDLAQHNCLTFHVNHKRHVAWRFEKDGAWTEVRVDGDRDADDAAIAHHWALAGAGLLYKSELDLVHDLREGRLVRLLPGWQGEPYPLNAILPSHRFVPARVRALVDFLAAKLRDLSPQKPGVPGARGLKR
>NC_021658.1|WP_187345819.1|14293934_14294684_-|SDR-family-oxidoreductase
MLSNKVVLITGATSGIGAATAIAAARAGAKVVLAARRQEMGDALVARIKVEGGNALFVRTDVTVEADIQALIERTVEAHGRLDSVFNNAGIATALGPLADVPVADYLALMQVNLHSIYLCMRYQVPVMKKGGGGSIVNCGSIASTVSAPGFGVYAATKHAILGLTKSAAIDYAADKIRVNAILPGPVETEIWDHMQSGEQVLDAFGAATLMKRYAHADEIARPAVFLLSDWSSYMTGTQLTVDGGYTAV
>NC_021658.1|WP_148314619.1|14296306_14296879_+|transposase
MLTFPFSWWRRLAQDGASFGVLTRIFVESVERFYETRAARRGACGAVKSGAVTDVQRTSGDMRLNPHLHVVFLDGAYHEDGTELVWNELGDLRTGEVGQVLEHAVGRMLRTLRRHGHLEIEHDVEEDDEPEAVLCASAVSGREPRHTSSPRNGSAGSRRLLRARSRTTSRCALRSMASPCTQRRAPVRTI
>NC_021658.1|WP_044987183.1|14297017_14297959_-|MBL-fold-metallo-hydrolase
MLRAASSTALMALLAASALSCNSMPGRVLSGNTGALFGGPAPVANKVREPYRKDARLAVLWVGHATALVQIDDKQILTDPVFTSTVGLLAARLVEPGLDPEHVPPLSAVLVSHTHFDHLSLGSLEMIEEKTPVLFVPRGALPYVPDFAFDTIELSTWQRWEHDGLRITAVPVKHGGGRYGVDIALGWGGFTGYVVEYHGITVYFGGDTAYDRKVFTETRARFPAIDLALMPIAPMGPRDFMHSRHVDPAEALEACEELGAKWMVPIHFDTFINSSDEPGQAASELKRVMAARRIAPGKVHILAPGEQRILLGR
>NC_021658.1|WP_063752111.1|14297963_14298698_-|hypothetical-protein
MARASCHRAEENATAPASGNVAPSPSSRCSASACARLRAAAGARLPCIARGGPATALRRSLAGAALAGALAWGSPARAAETQSLAEAGISPDLAWAASQLIPSPTWHLYADDTRFGLRWQLTPLLYSFGRNRRLSPWRSLLAEPLARHAGALEIHVTPEYLFSGAGIEDHVQLTGGVRAYFPLLHRGEYLSCSLGGSAFTLGGEVAAAYEAGLYTLFGVIGVQVAYSPTRALRGTTLTLNLRYF

Crispr_ID: NC_021658_64

• CRISPR_ID: NC_021658_64
• CRISPR_location: 14326570-14326669
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_64

Consensus_repeat	Method
GGCATACTAACTTGCTTGTGGCC	CRISPRCasFinder

spacers of NC_021658_64

>64.1|14326593|54|NC_021658|CRISPRCasFinder
TGTGGCTCTCGGCGGTCCGCCCGTGTCGGCGGCCCGCGCGGGAACAATCCGTTA

CRISPR arrays and Neighbor proteins around NC_021658_64

CRISPR arrays

The CRISPR arrays of NC_021658_64

>merge|NC_021658|64|14326570-14326669|CRISPRCasFinder
GGCATACTAACTTGCTTGTGGCCTGTGGCTCTCGGCGGTCCGCCCGTGTCGGCGGCCCGCGCGGGAACAATCCGTTAGGCATACTAACTTACTTGTGGCC

>NC_021658|64|56|14326570-14326669|CRISPRCasFinder
GGCATACTAACTTGCTTGTGGCC	TGTGGCTCTCGGCGGTCCGCCCGTGTCGGCGGCCCGCGCGGGAACAATCCGTTA
GGCATACTAACTTACTTGTGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_020742033.1|14315583_14316168_-|SgcJ/EcaC-family-oxidoreductase	unknown	unknown	gnl|CDD|274053
NC_021658.1|WP_044989866.1|14326740_14326950_+|TOBE-domain-containing-protein	unknown	unknown	gnl|CDD|273189
NC_021658.1|WP_148314623.1|14323547_14324234_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020742048.1|14335223_14337233_+|hypothetical-protein	unknown	unknown	gnl|CDD|214599
NC_021658.1|WP_044987189.1|14321763_14323086_+|patatin-like-phospholipase-family-protein	unknown	unknown	gnl|CDD|132848
NC_021658.1|WP_020742047.1|14333062_14334967_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|227333
NC_021658.1|WP_020742042.1|14324261_14325587_+|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|238113
NC_021658.1|WP_020742037.1|14319542_14320127_-|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl|CDD|234786
NC_021658.1|WP_020742034.1|14316262_14317288_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381317
NC_021658.1|WP_020742043.1|14325597_14326527_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486
NC_021658.1|WP_148314624.1|14329090_14333017_+|DUF4215-domain-containing-protein	unknown	unknown	gnl|CDD|162730
NC_021658.1|WP_148314622.1|14318234_14319461_+|cellulase-family-glycosylhydrolase	unknown	unknown	gnl|CDD|365907
NC_021658.1|WP_020742051.1|14338833_14339202_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380344
NC_021658.1|WP_020742053.1|14340671_14341583_-|methylenetetrahydrofolate-reductase	unknown	unknown	gnl|CDD|236321
NC_021658.1|WP_020742039.1|14321166_14321535_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_148314625.1|14338354_14338819_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380360
NC_021658.1|WP_020742038.1|14320170_14320842_-|DUF4291-domain-containing-protein	unknown	unknown	gnl|CDD|379483
NC_021658.1|WP_020742049.1|14337267_14338299_+|FHA-domain-containing-protein	unknown	unknown	gnl|CDD|238017
NC_021658.1|WP_020742045.1|14326992_14328513_-|Do-family-serine-endopeptidase	unknown	unknown	gnl|CDD|273938
NC_021658.1|WP_020742052.1|14339456_14340620_+|flavin-reductase	unknown	unknown	gnl|CDD|214900

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_020742033.1|14315583_14316168_-|SgcJ/EcaC-family-oxidoreductase	gnl|CDD|274053	TIGR02246, hypothetical_protein, conserved hypothetical protein. This family consists of uncharacterized proteins found in a number of genera and species, including Streptomyces, Xanthomonas, Oceanobacillus iheyensis, Caulobacter crescentus CB15, and Xylella fastidiosa. The function is unknown.	6.44197e-13
NC_021658.1|WP_044989866.1|14326740_14326950_+|TOBE-domain-containing-protein	gnl|CDD|273189	TIGR00638, Probable_molybdenum-pterin-binding_protein, molybdenum-pterin binding domain. This model describes a multigene family of molybdenum-pterin binding proteins of about 70 amino acids in Clostridium pasteurianum, as a tandemly-repeated domain C-terminal to an unrelated domain in ModE, a molybdate transport gene repressor of E. coli, and in single or tandemly paired domains in several related proteins. [Transport and binding proteins, Anions].	1.77897e-14
NC_021658.1|WP_020742048.1|14335223_14337233_+|hypothetical-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	1.60766e-52
NC_021658.1|WP_044987189.1|14321763_14323086_+|patatin-like-phospholipase-family-protein	gnl|CDD|132848	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli. Patatin-like phospholipase similar to Z1214 protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	3.22862e-27
NC_021658.1|WP_020742047.1|14333062_14334967_-|HAMP-domain-containing-protein	gnl|CDD|227333	COG5000, NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms].	4.61187e-46
NC_021658.1|WP_020742042.1|14324261_14325587_+|trypsin-like-serine-protease	gnl|CDD|238113	cd00190, Tryp_SPc, Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues.	6.19435e-17
NC_021658.1|WP_020742037.1|14319542_14320127_-|50S-ribosomal-protein-L11-methyltransferase	gnl|CDD|234786	PRK00517, prmA, 50S ribosomal protein L11 methyltransferase.	1.578e-47
NC_021658.1|WP_020742034.1|14316262_14317288_-|aldo/keto-reductase	gnl|CDD|381317	cd19091, AKR_PsAKR, Polaromonas Sp. aldo-keto reductase and similar proteins. The prototype of this family is an uncharacterized aldo-keto reductase from Polaromonas sp.	8.19968e-147
NC_021658.1|WP_020742043.1|14325597_14326527_+|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.3836e-40
NC_021658.1|WP_148314624.1|14329090_14333017_+|DUF4215-domain-containing-protein	gnl|CDD|162730	TIGR02148, ORFveg106_random, fibro-slime domain. This model represents a conserved region of about 90 amino acids, shared in at least 4 distinct large putative proteins from the slime mold Dictyostelium discoideum and 10 proteins from the rumen bacterium Fibrobacter succinogenes, and in no other species so far. We propose here the name fibro-slime domain.	8.99879e-17
NC_021658.1|WP_148314622.1|14318234_14319461_+|cellulase-family-glycosylhydrolase	gnl|CDD|365907	pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5).	2.46075e-46
NC_021658.1|WP_020742051.1|14338833_14339202_+|cupin-domain-containing-protein	gnl|CDD|380344	cd02214, cupin_MJ1618, Methanocaldococcus jannaschii MJ1618 and related proteins, cupin domain. This family includes bacterial and archaeal proteins homologous to MJ1618, a Methanocaldococcus jannaschii protein of unknown function with a cupin beta barrel domain. The active site of members of the cupin superfamily is generally located at the center of a conserved barrel and usually includes a metal ion.	2.49973e-11
NC_021658.1|WP_020742053.1|14340671_14341583_-|methylenetetrahydrofolate-reductase	gnl|CDD|236321	PRK08645, PRK08645, bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed.	1.97349e-40
NC_021658.1|WP_148314625.1|14338354_14338819_+|cupin-domain-containing-protein	gnl|CDD|380360	cd02232, cupin_ARD, acireductone dioxygenase (ARD), cupin domain. Acireductone dioxygenase (ARD; also known as 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase) catalyzes the oxidation of 1,2-dihydroxy-3-keto-5-methylthiopentene to yield two different products depending on which active site metal is present (Fe2+ or Ni2+) as part of the methionine salvage pathway. The ARD apo-enzyme, obtained after the metal is removed, is catalytically inactive. The Fe(II)-ARD reaction yields an alpha-keto acid and formic acid, while Ni(II)-ARD instead catalyzes a shunt out of the methionine salvage pathway, yielding methylthiocarboxylic acid, formic acid, and CO. ARD belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.44075e-30
NC_021658.1|WP_020742038.1|14320170_14320842_-|DUF4291-domain-containing-protein	gnl|CDD|379483	pfam14124, DUF4291, Domain of unknown function (DUF4291). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 190 and 214 amino acids in length. There are two conserved sequence motifs: VYQAY and RMTW.	1.67388e-98
NC_021658.1|WP_020742049.1|14337267_14338299_+|FHA-domain-containing-protein	gnl|CDD|238017	cd00060, FHA, Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).	3.74283e-18
NC_021658.1|WP_020742045.1|14326992_14328513_-|Do-family-serine-endopeptidase	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	7.32236e-166
NC_021658.1|WP_020742052.1|14339456_14340620_+|flavin-reductase	gnl|CDD|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	8.92147e-50

Protein sequences

>NC_021658.1|WP_020742043.1|14325597_14326527_+|phosphatase-PAP2-family-protein
MEALDLRADQLASAVGARPVLLLALLLTGTVGVLLGLVAVARLSERHARALWGRAAGAYRAAAEHPITQRLSARFPAIARVLRDLSASEYLVIHLGLGLALTLAALVFVAIAEAVSGDAWIVQVDLALARALHGSSSSAGVTALGAFTHLGSGWALTALAIVVAAALLMRRQRVLAVGWLIALAGGGLLNQALKALFARPRPLFDEPLAVAAGWSFPSGHSMGTFVTFGMLSYLGLLFLRTLRARLALVAFALSWTVAMGFSRMYLGVHYLSDVLAGFAAGSMWLAVCISGIEVARRRPGRAGVQPLPA
>NC_021658.1|WP_020742042.1|14324261_14325587_+|trypsin-like-serine-protease
MTARIARGPLAAALLLLHGAGCAPAGDDAPPSSAEARQEVRNGTPAAEDAAVVGIAVGGEVGCTGVLIRPRVVLTAAHCLVGHRPDTVLVGPSATDGVHVGVAQAWSSPDYRAGAADHDLGALLLREPLDAAPIPLSARPLAEEDAGRSVRFVGFGREDPEERGEGRRMQGTAVLGELAALTFSLTPSPSSACSGDSGGPVVGARDEGEVLLGVISRGDEACAERASAVRVDAHLGGFIEPLLALIEQTAGQPGERCVEADNCASGLCVAPEDAPSFPYCSRACEGPADCPAAMRCERGGPGPPHCRYTGPSPGAIGAACDRDEACEFGMCARFDGGVDGEERPTCSALCFPEDPEPCPHGGVCSPRVDAARAHGCKAEAPARPAAAGGCAAGRALPGAAASPGWRLLLAAGALSVGLRALRRSAARRRGARPRRTGRGAC
>NC_021658.1|WP_148314623.1|14323547_14324234_+|hypothetical-protein
MGRVLLRLVAFAAVGALAFVGCSVESGPESAGEPQAEEGAETLTVELEGSVAHAVRIDASQVRVDIYDRAGVLQFSADYRAIEGQMPSVAWTLFQPAAAGEPAAAAASGALEVEMDELPTLDGAVTGAALIHAQVSRADSSEAYDNWGCDLLPGAYNGIVSCGTKGACCDVHDACFATYGCNAGSWTRPWDYAWQCSAICNAGAVGCFTSLHPGPSECCWLGNCGQPR
>NC_021658.1|WP_044987189.1|14321763_14323086_+|patatin-like-phospholipase-family-protein
MSDHDLSDQEYKAAYWAGCEGVPEGRVALVLTGAGARGAYEAGFVSRLLPELKQSRPKILVGTSAGAINAALLATLGHRTAEDVSREIVERWQRIHKDMVLGSVWVSLLRAGIKYVASLLLGTEGPRSLLDTSPLLFNLKNQTLIDWDIINDNINNINEDEEPCVDVLAVVTTESGSGRTKVFYQTRREDLATVSSDDLRGIDYVRTRLSPEHVLASAAIPVLFPPTFIGSPARGRFFVDGGLRLNAPLTPAMAFHANHIIVVSTDSRRYGSSAAASIRRSPSMQDHILQIMRVITSDRMVEDVRGLLEQNRLLLKIARDKMERGELREQDRVAIIFGGPSGQDDVGSVAARALEDILRGTRKLNHLDLSLLYWLTSVNPYSRPDVLSYVLFEPEFISAAIRAGIQDADELIEDNPTERELWTAMCRRYEKKIERAEGHR
>NC_021658.1|WP_020742039.1|14321166_14321535_+|hypothetical-protein
MAYDEVLDQVTCPECKASFEMTTQITFGYCRGHRLRPGDEILWCDPRGRRAPLLDLDENLGGELLVPGAGDEACPSCRAVLPNAHVLEKRRYIGTSSLNCGTCPGLAELPSMRSDTFLEKRC
>NC_021658.1|WP_020742038.1|14320170_14320842_-|DUF4291-domain-containing-protein
MEKLVLEPYAAQAARWPAAGRHILAQFDAETIVVYQAYRPSIARHAALHQRLGGPEFSFGRMSWIKPNFLWMMYRSGWGTKPDQEAVLAIRLRRAGFDAILAAAVPSSFVPELYPSQEAWNRDLKRSDVRLQWDPDHHPSGAPVARRAIQLGMRGAALRRFAEEWTVGVADISELVAEQREALRGRGTSGLVIPREEVYWPAEAEGARRVGLERWAGGEERGR
>NC_021658.1|WP_020742037.1|14319542_14320127_-|50S-ribosomal-protein-L11-methyltransferase
MSDRPTIVDVPPRFRVVTGPWDAEADERTIVLGPSHAFGDGRHESTRMCLQALAAFAPRGGFRLLDVGSGTGILSIAAAKLGGEAFGVDIDAAAIAIAAESARRSAVEARVRFATTWPDGSFDIVVANILRDVLTELAPLIAARLAPLGTLILSGLVSTDVPEIVARYAPLLAGRRPEIFERGAWRTLVWRLAA
>NC_021658.1|WP_148314622.1|14318234_14319461_+|cellulase-family-glycosylhydrolase
MLVAVGCSSESSTSGNAAGSGGGTDTSGADTGGAGTSGAGTGGAGAGDAGTGGAGTGGAGGSGGSGGSATPVDAAAMVPDMGIGTNIGNTLENTTEWETGWGQPLITQAFINGMASHGIKTVRVPVAWDTYAANGTIDAAKMARVKEVVGWIEAAGMYSIVNIHWDGGWIYNEANANKYKLTDDVKTRFASYWTQIATAFSDVGHKLILEGMNEEGNYWVNGVHDGGTPDYAALNEMNQLFVSTVREQGGYNASRALLISGFVTDIDRTCVSDFKVPTDPAGTKSLFLSIHYYTPYTFCGLDTVESWGSPKTTWGTDAEKAELKGLFDKLGAFSAERSIPVILGEFAVTLGQNYPREPASRRLWMQSVVEAARSRGIVPVLWDTGSEIKRTDGSFSTEWQAVMDAVDP
>NC_021658.1|WP_020742034.1|14316262_14317288_-|aldo/keto-reductase
MEYRSLGTSGLKVPVLCLGAMTFGEADEKSFMHKVGCDEKTSFAIMSRALERGVSFIDTADVYGQDGLSERIVGAWMAEAKSRDRVVLATKFRFRMGEGPNSSGASRYRIVRTVEDSLRRLKTDRIDLYQIHMQDIETPEEETLRALDDLVRAGKVLYLGASNYAAYRLTDSQWIAKTEHLHRFVALQMQYSLLVRDLEREHIPVCKRFGIGVLPWSPLAAGFLSGKYAKDQPPPQGVRLEKWKQRFADYDNDRGWRTLDAVNAIAKEKQTTPAAIALAWLLAKPTVTSVIFGARSLEQLDDNLKAADVKLSAEEVQRLDDASAFEIGYPYNFIGNVQKRW
>NC_021658.1|WP_020742033.1|14315583_14316168_-|SgcJ/EcaC-family-oxidoreductase
MHRALATAALPLLLLACATASPPPSAPAAPAPTAPAPAAAAAAPDARAQQALGEQLVAAFNDTWNRHDMDAFAALHAEDADFVNIFGMWWHGRATIRENHAGIHKTVFRQSRLESVRVETRFVAPDVAVVRWAWVLTGVLTPDGKPAPDMQGILVHVARLQGDRLQFVTTQNTQATADAFRAVRGAEPQGRPAQ
>NC_021658.1|WP_044989866.1|14326740_14326950_+|TOBE-domain-containing-protein
MQISGRNKIPGKITEIVVGDVMAKVVMEGPGGTELVAVITSDAVKELGLSVGKEVQALIKATEIMVIAK
>NC_021658.1|WP_020742045.1|14326992_14328513_-|Do-family-serine-endopeptidase
MHARWAVPLAVITALPLGCLDRAERRVEQIAEATPPPAPGPLDVPPSAREAVSLQEGFAPIVSRVSAAVVNVSSVRFVRPPAPERVPFFSNPFFREFFGMGGDGRDGRDDRSGQEGQAPGPLVQREQSLGSGVIVSREGHVITNAHVVQGATQVRVAVPGRQEMKATVVGVDAKTDVAVLKLEGGELAFAPFGDSDAVRVGDFALAIGNPFGIGQTVTQGIISAVGRGNMGIVDYEDFLQTDAAINPGNSGGALINMAGELIGINTAILARGAQGNQGIGFAVPSKLARAVMEQIVEHGRVIRGALGVAIQDVSPGLAEALGLPPDTRGAVVSDVSEGSAADKAGLRRGDVIVALRGEHLDDGRDLRMRIAETKPGTGVELRVLRDGRSLELTATLDELPEPKAEALTPAPTPTGALGIEVAALSDDLRRRFEIPGDVKGALVVGLSPGSPAARAGLGPGDVLLEVNRKPLTGPEQLKQEVDATDKRPVLLLAWREGRTRFVLVER
>NC_021658.1|WP_148314624.1|14329090_14333017_+|DUF4215-domain-containing-protein
MAVGLRTSYLALALGLLQITAGCGGDVSSPGDATGSGSGAGTGTGGPGSGGAGGEPEFTVGSGPGLGGSGAGEPDPCDVDEPPPECFLPPDPACGDGAKNQEAEACDDGNTLPGDGCSGQCQVEPYWECTTPGQPCRLTIACGDGILHPGEFCDDGNTADDDGCSADCLYVDSSYVCPRPGEPCILLYDCGDGRVNGSEECEDGDDPPASGDGCDAECKREDGYQCSRPGQPCTPLPVCGNGDKETGEGCDDGNATSGDGCSGLCRQEPYYYCPTPGSPCERLIECGDGEVQPGELCDDGNAADGDGCSADCQVRDPNYVCPEPGEPCILLYRCGDGRVNGAEQCDDGEAVPESGDGCTADCRLEEGWVCRPGQPCTVRTFCGDGVVQVGEQCDDGGGASPAGGDGCTAQCKIELGWTCPPAGGACTPPPPPVCGDGVIGGDEVCDDGDDPPASGDGCSADCRTIEEGWDCSRVGFACKTVCGDGIKLGAEQCDDGDLASGDGCDNRCRIEPGRVCDDGEPQDCTGRSVCGDGVREGTEVCDDGDGNWRDGCTPDCKREPDCSGGACTSQCGDGILLPGDAAEQCDDGNTESGDGCSATCRIEAGYVCSVAPTEMRLPMVIRDFIGWCPRDIAASNTECDARLTDRLIGHFDFEITPSGTTLQTDGTVEPTLDGEGKPVNAHGDGYFEAASSNGWTTGQENFQWWYRDNPDFNRTLVTSIQLTETPAGSGRYVYQRNPFWPVDLDPPGADPALDSLVAAGLERTRDSGHNFYFTSEVRYWFQHRSDGNASNNPVLTFYGDDDVWVFIKNTLTADIGGIHGRAEESVTILDNGDAQVTPCPTSSGCPNRAAYTVDLNLEHGKVYEIVVFQAERHVTGSNYQLTLAGFSAGKSACTPQCGVNPPVVTPGEECDDGTKNGTGYGECNDCLLGPYCGDRVKNGPEACDNGVNNSTYANASGACAPGCVAPPRCGDGQVNAPYEACDLGSGNTANGYGGCTTECEIGPSCGDGEVNGPEQCDDGKNDGFYGTCNPNCTRAPECGDGRVDEEWGEECDDPTDANCVGCQLGAHCGDAVVQSNYGEECDDGRNDGGYGECAPMCLYGPRCGDGVVQPDEEDCDLGEGMNTGAYNGCNDSCSYGPYCGDAVVNGAETCDDGVNDGFYGSCFPDCTPAAQCGDSHVDEEWGEQCDPPNEATGCSDNCRLGAQCGDSVVQAHLGEQCDDGKNDGGYGECGPQCKYGPRCGDGVVNGSEQCDDGDGKNTGGYGKCAPGCKYGPYCGDGERQSAYEECDDGNNKSGDGCSSACEYDSQPL
>NC_021658.1|WP_020742047.1|14333062_14334967_-|HAMP-domain-containing-protein
MHGDAAEKDRRGGSARAPVPPGSTLNTAADRGGRPAVLAAGVATRPGRPAMPLAARLLLAFGLVAIIATAFVGLTLREASREIIESGFADRIDAAHAGVRQQLAWEAEALRDLLPPFCQHDTFVDKAHVELERAKGDPDAMDPTSRIALRRLVPSQAKALRLDELSLVAGNGSVLAAEDASRIGARDPRLAEAIKAPGGAPRLRPAKAGGEPSLEVHCALSRHGVTIGLVGARRIGPVLARIGDAYHVRLTAAPEGRPAPRSGEAEVVRVLDFPEIPGLDVVASVSREPLRQALARLDRSIALTGATVLAIALGIAVVLARSLSRPIAALARETREVMSGAPRRVEGRGGREIADLAAAFNATIDELAAMRKRLAATERIAARREVARQIAHEIKNPLAPIRAAVETLRRLRQREDPAFDDYFEEATSTVLNEVHRIANIVTEFTRFARLPAPNPEPVDLVAIARGVVTLHAAPAGEETGGTTGGAASPRVELVAEPIPKVSADRDQLIQVLTNLVQNGLEAAGAVRRDPRVSVTIGPLPNDRVRIVVRDNGPGVAEDMVPRLFEPYATSKEKGTGLGLAIAQRIVFEHGGEIGYRKAQKGGAVFEIWLPVGGPPLLEKPPGDTTVRPRAPDVP
>NC_021658.1|WP_020742048.1|14335223_14337233_+|hypothetical-protein
MNSKQLSIAIAVVLVLVGFGLSFASKPLAEFSGQLFGLFGFAAAVAVLYASLADKGGAPLGGLRDALRAAARGKRPKLPEGAPADVAETYEQIAELAGRQAELVEERHALAEERDKLARERDGLSRERDGVERQRDALERERDSLSRERDGLLKERDGLTKERDTLERECANLTRKVNDLAQRGPDIDVDALVDAVLRATAGERVRVPPGAPPELSRLYSELTGIAERVTQSELRDKQRRSELAQATVLLDELLPKLSDGVSSVMHASEQATVYIRDMTTALANIAQSVESLASSAEESSSSILEMTATNEEVAENVGELGSSVRETVSSIEEMAYSIREVAKNVDALALTAEETSSSMNQMDVSIDQVQSNANETARLSEEVATDAEKGAEAILKTIGEIYRIKESSQEAVAVISNLGFRIEAIGQILAVIDDVAEQTNLLALNAAIIAAQAGEHGKGFAVVADEIKDLAERAGGSTKEIAELIKTIQSESKNAIAAVERGAHNVDRGVEVSNEAERALKKILESSQKSTNMVRAIARATVEQAKGSKQVTDAIGRIAETVQQIAAATAEQARGSELIMKSAEKMRTITQHVERSSQEQARGGRQITSAIEQISNQVHSLNASHRSQTRGGEQLIEAGKRIEEAARQQDQAVRQLVSATERMRRTAAI
>NC_021658.1|WP_020742049.1|14337267_14338299_+|FHA-domain-containing-protein
MALTIVVLSPGGAGNSPGGAGKEGELSLTLDAPRVILGRAEGCEVRLPDTSVSPRHASIRQRGATYLLLDEGSENGTFLGKTRIAPRTAMPLRTGDRIRVGRVWLALRIEPAVPKASPAAAAKELALELVARGLAAQGEDPTPRVVVVDGPDRGRALHVEAPGRPYFVGRAQDADFTLDDPDVSRRHVAITRRGDQFSVQDLGSRSGASLDGVPVPQFDTVWRPGQVLAISADRLVFEHPAAEALAEIERSPCEPLPADAAVELPSADEPSAASSAPSSAPTSTPTPSPASASTLSPLARPAAAAPRVAQGGGWGFTEALIALLALGVLALSIAGLMWLLGRG
>NC_021658.1|WP_148314625.1|14338354_14338819_+|cupin-domain-containing-protein
MRAIRMSAEGEIEFTEAELQAEGIRCGTFDPSAAALALQRVHAERGWTEHDEVRRDTSNPRDEAESAREADEHCHLGDEVRLFLEGQALYDVRCMNDEWMRIWVGAGDLVVVPARRYHRFVASKAAALRYLQPYGGRHLLMQLYRVSDDRTRAF
>NC_021658.1|WP_020742051.1|14338833_14339202_+|cupin-domain-containing-protein
MARPYRLVTSATRIPVPGGKLIEELFGRVNTGTDGFSLAHMVAPPGWSEPAQTPAFGELTLMIRGRMRVEIAGETVDLSAGQAIWTEPDQRVRYSNPFDEESEYFALCIPAFAPDLARRDAG
>NC_021658.1|WP_020742052.1|14339456_14340620_+|flavin-reductase
MLFDPAEFRKVLGQFATGITLVTTVQDGTPQAMTVNSFSAVSLDPPLVLFCADRRSRTSAAIEASGVFAVNILREQQRDISDLFAGKGTDIDRQAVLTEAHVAESGSPILKDVLAFIDCKVEHAYDGGDHIIYVGRALSSGRGEAGAPLLYYRGTYQALDDVWRWRDRYAAKEQATPFHELVDFFDRMQAEGPYATLIDELVTLADPGVEERCLDLGCGTGRLTREMGRRCHEAVGIDATAAMIERAAQRAKALGLDNVTFREALATRLPFPDASFDVVTASNLLLHVPEPGPVLAEAARVLRPGGRLALLEPAPGMNRVAMAGYLRGHRYNPPTAHAMLAWADAAEVTYRHTEDRLNADLSGTGFEIDRRERRMNGLALLWIAHKG
>NC_021658.1|WP_020742053.1|14340671_14341583_-|methylenetetrahydrofolate-reductase
MVSKSKMERLLSERQFLVSAELTPPRHYDLEKLLKHARNMAGCVDVVQINDHLLSQARCANMAVGHFVKQEGLEPVLQFSLRHKNRIALQGDLLGMAALGLSNIIILGGYPCAIGSDPEAKEVSDVDSYAAIELTRRMTREGRLYNGDVISPAPYFHVGTIDFPCGEQAIAGAMDRLSAKIDAGASFIQVQAVFELAPMRRWMAAVVERGLHERAHFIAAIFPFAGVDRLSFLQKVPGLVVPEHLIERVRQSGDAEGESYRITLELVRGLRDVPGLSGIHMRSIGAEDWVPRLVEEAGLRRAA

Crispr_ID: NC_021658_65

• CRISPR_ID: NC_021658_65
• CRISPR_location: 14564502-14564596
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021658_65

Consensus_repeat	Method
GCGGCGTGCGATGATCGGCGCGC	CRISPRCasFinder

spacers of NC_021658_65

>65.1|14564525|49|NC_021658|CRISPRCasFinder
CGATCGGGCCGGGGGGGCTGGCGAGCCCGCGCGGGACAGCGGCGCGGGC

CRISPR arrays and Neighbor proteins around NC_021658_65

CRISPR arrays

The CRISPR arrays of NC_021658_65

>merge|NC_021658|65|14564502-14564596|CRISPRCasFinder
GCGGCGTGCGATGATCGGCGCGCCGATCGGGCCGGGGGGGCTGGCGAGCCCGCGCGGGACAGCGGCGCGGGCGCGGCGTGCGATGATCGACGCGC

>NC_021658|65|57|14564502-14564596|CRISPRCasFinder
GCGGCGTGCGATGATCGGCGCGC	CGATCGGGCCGGGGGGGCTGGCGAGCCCGCGCGGGACAGCGGCGCGGGC
GCGGCGTGCGATGATCGACGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021658.1|WP_044987232.1|14561984_14563070_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_021658.1|WP_020742202.1|14551750_14554456_+|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl|CDD|274542
NC_021658.1|WP_020742217.1|14574879_14575581_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227305
NC_021658.1|WP_044987234.1|14570438_14571953_-|pilus-assembly-protein-PilM	unknown	unknown	gnl|CDD|227306
NC_021658.1|WP_020742216.1|14574202_14574880_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|225076
NC_021658.1|WP_020742212.1|14569839_14570442_-|type-II-secretion-system-protein-M	unknown	unknown	gnl|CDD|377391
NC_021658.1|WP_020742211.1|14566607_14568452_-|response-regulator	unknown	unknown	gnl|CDD|132912
NC_021658.1|WP_044987233.1|14568544_14569843_-|type-II-secretion-system-protein-GspN	unknown	unknown	gnl|CDD|275204
NC_021658.1|WP_020742210.1|14564633_14566565_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|226654
NC_021658.1|WP_020742205.1|14556578_14556908_+|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020742206.1|14556935_14559236_-|DUF2169-domain-containing-protein	unknown	unknown	gnl|CDD|370755
NC_021658.1|WP_148314645.1|14554968_14556567_+|PAAR-domain-containing-protein	unknown	unknown	gnl|CDD|269827
NC_021658.1|WP_020742214.1|14571980_14573483_-|general-secretion-pathway-protein-GspK	unknown	unknown	gnl|CDD|377165
NC_021658.1|WP_148314646.1|14559276_14560512_-|hypothetical-protein	unknown	unknown	unknown
NC_021658.1|WP_020742218.1|14575603_14576008_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|130771
NC_021658.1|WP_020742209.1|14563124_14564468_+|threonine-synthase	unknown	unknown	gnl|CDD|178182
NC_021658.1|WP_148314644.1|14554519_14554954_+|DcrB-related-protein	unknown	unknown	gnl|CDD|370123
NC_021658.1|WP_020742215.1|14573486_14574206_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227132
NC_021658.1|WP_020742208.1|14560569_14561922_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274522
NC_021658.1|WP_020742201.1|14550695_14551706_+|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|376570

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021658.1|WP_044987232.1|14561984_14563070_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.84307e-100
NC_021658.1|WP_020742201.1|14550695_14551706_+|GAF-domain-containing-protein	gnl|CDD|376570	pfam01590, GAF, GAF domain. This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl cyclases, phytochromes, FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP, respectively, these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. Here too, cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum, while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54.	7.02804e-09
NC_021658.1|WP_020742217.1|14574879_14575581_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	1.98848e-05
NC_021658.1|WP_044987234.1|14570438_14571953_-|pilus-assembly-protein-PilM	gnl|CDD|227306	COG4972, PilM, Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion].	6.38452e-13
NC_021658.1|WP_020742212.1|14569839_14570442_-|type-II-secretion-system-protein-M	gnl|CDD|377391	pfam04612, T2SSM, Type II secretion system (T2SS), protein M. This family of membrane proteins consists of Type II secretion system protein M sequences from several Gram-negative (diderm) bacteria. The precise function of these proteins is unknown, though in Vibrio cholerae, the T2SM (EpsM) protein interacts with the T2SL (EpsL) protein, and also forms homodimers.	8.22241e-05
NC_021658.1|WP_020742211.1|14566607_14568452_-|response-regulator	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	3.10048e-42
NC_021658.1|WP_044987233.1|14568544_14569843_-|type-II-secretion-system-protein-GspN	gnl|CDD|275204	TIGR04411, hypothetical_protein, type II secretion system protein N, Leptospira/Geobacter-type. Members of this family are the N (or GspN) protein of type II secretion systems (T2SS) as found in Leptospira, Geobacter, Myxococcus, and several other genera. Sequence similarity to GspN as found in, say, Gammaproteobacteria (see pfam01203) is extremely remote. [Protein fate, Protein and peptide secretion and trafficking].	5.02494e-30
NC_021658.1|WP_020742210.1|14564633_14566565_+|HAMP-domain-containing-protein	gnl|CDD|226654	COG4191, COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms].	4.17565e-26
NC_021658.1|WP_020742202.1|14551750_14554456_+|type-VI-secretion-system-tip-protein-VgrG	gnl|CDD|274542	TIGR03361, VI_Rhs_Vgr, type VI secretion system Vgr family protein. Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.	0
NC_021658.1|WP_020742206.1|14556935_14559236_-|DUF2169-domain-containing-protein	gnl|CDD|370755	pfam09937, DUF2169, Uncharacterized protein conserved in bacteria (DUF2169). This domain, found in various hypothetical prokaryotic proteins, has no known function.	2.26645e-79
NC_021658.1|WP_148314645.1|14554968_14556567_+|PAAR-domain-containing-protein	gnl|CDD|269827	cd14742, PAAR_RHS, proline-alanine-alanine-arginine (PAAR) domain, also containing C-terminal Rearrangement hotspot (Rhs) extensions. This PAAR (proline-alanine-alanine-arginine) repeat subfamily, which forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS), contains C- and N-terminal domain extensions. These include Rearrangement hotspot (Rhs) protein repeats and conserved Rhs repeat-associated unique core sequences at the C-terminal, and various predicted functions at N- and C-terminal extensions. However, these terminal domains are exposed to solution, and do not distort the binding site of VgrG. Rhs and related YD-peptide repeat proteins are widely distributed in bacteria. Rhs shares similar architecture with distantly related WapA proteins of Bacillus and Listeria species, suggesting intercellular growth inhibition as its primary function. Additionally, a plasmid-encoded Rhs protein has been implicated in bacteriocin production in Pseudomonas savastanoi. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes.	1.07972e-14
NC_021658.1|WP_020742214.1|14571980_14573483_-|general-secretion-pathway-protein-GspK	gnl|CDD|377165	pfam03934, T2SSK, Type II secretion system (T2SS), protein K. Members of this family are involved in the Type II protein secretion system. The T2SK family includes proteins such as ExeK, PulK, OutX and XcpX.	3.73806e-16
NC_021658.1|WP_020742215.1|14573486_14574206_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227132	COG4795, PulJ, Type II secretory pathway, component PulJ [Intracellular trafficking and secretion].	1.02304e-05
NC_021658.1|WP_020742218.1|14575603_14576008_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|130771	TIGR01710, Type_II_secretion_system_protein_G, type II secretion system protein G. This model represents GspG, protein G of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	2.75231e-08
NC_021658.1|WP_020742209.1|14563124_14564468_+|threonine-synthase	gnl|CDD|178182	PLN02569, PLN02569, threonine synthase.	0
NC_021658.1|WP_148314644.1|14554519_14554954_+|DcrB-related-protein	gnl|CDD|370123	pfam08786, DcrB, DcrB. DcrB is a bacterial protein required for phages C1 and C6 adsorption. It may be involved in the opening or formation of diffusion channels in the outer membrane. Structurally, it consist of an antiparallel beta sheet with some alpha helical regions.	3.20921e-29
NC_021658.1|WP_020742208.1|14560569_14561922_+|FAD-dependent-oxidoreductase	gnl|CDD|274522	TIGR03329, Phn_aa_oxid, putative aminophosphonate oxidoreductase. This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.	3.01766e-63
NC_021658.1|WP_020742216.1|14574202_14574880_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	4.10644e-06

Protein sequences

>NC_021658.1|WP_020742209.1|14563124_14564468_+|threonine-synthase
MAYSAAFRCLTGCPGSYPLTQPLYRCPTCGGLLDVAHDIDALRDRSPATWMKLFDERYKRTVWPYGSGVWGKREWVAPQVPDEAIVSMDEGGTNLFWADRYGRSLGLDDVWVKLCGNSHTGSFKDLGMTVLVSVVNKAIREGLEVRAIACASTGDTSASLAAYGAAAGLPVVVLLPRGKVSMAQLVQPIASGALVLSLDTDFDGCMAIVQRLSADGVVYLANSMNALRLEGQKTVAIEIVQQFDWTLPDWVVLPSGNLGNAYALYAGFKMLKDLGLTTRFPRLCVAQSARANPLYRAWAEGRSEVVPMKAGETLASAIQIGNPVSAPRAMMALQAMNGVAEEVTEDELCDAAARADRTGMYTCPHTAVALAALEKLVKKGLVEKRQRVVVVSTANGLKFTEFKVKYHERALPDVTSRLANPPVELPPDYDRVLAALDKHAAQTGKKR
>NC_021658.1|WP_044987232.1|14561984_14563070_+|serine/threonine-protein-kinase
MFCARCHREYDAGHRFCPYDGGELAEARRVDLFRYKPTRLRGTILGERYEVRGYLGKGAMARVYLAIEIETGQPVAIKVLEAFAARAERTRERFVREAQSAAKIGHPNIVKVLDAGTRAADGAPYIVMEYLFGESLGDWLRRERRMDADLAIPVLSQAASGLAAAHRVGIIHRDVKPDNLYLVGAQGDPYAVKVLDFGLAKIQDADHITATGTAVGTLEYMAPEQVVSDRPDARTDVYGLGVVMFRTFTGELPFPRSEQSELLARQLVTPPPRPSEKRKSIDLQLEAVILKAIRKRPENRYPSMEAFLEDLERLAGERDGPLSADEPLPEPDDVYVPQGSFARNAAIYFYRRLGMEAPRFD
>NC_021658.1|WP_020742208.1|14560569_14561922_+|FAD-dependent-oxidoreductase
MTQAALVDTRTQIDSARSVWSEAGPVYEPAPPLRGDAVADVAIVGGGFTGVSTAYHLIRRFPSLRVVILEARHLANGASGRNGGMMLNWINGVSYRDPELTRRVYEATRAGIDGIVAMIQEHNLPVRYRRDGCMEVLTDARRAEAAHARAEQLAGWGIPLQFLDGAALAKRLGVRGAAGAVLDATEGQLNGVDLLRGLRPLLLGWGVALHEDTPVLRIQEGRTIELTTPGGVVRASAIVLATNGYTPRLGYFKTGIFPLHSHVIATEPLDAEARAALGWGQVAGFSDDHDRIAYASMTPAGELVFGGGSNAAYAYLYGNRTSYPGSPDSAARAFEAIRRRLVGYFPAAERVRIAHRWTGTLGITMSRICSMGVRGEHRNVYYALGYSGHGVTLGNLAGRVLCDIYAGDDARWRDLPFYMYPLGGVPPEPLRWLGYHVYTKLTGRSPRKAA
>NC_021658.1|WP_148314646.1|14559276_14560512_-|hypothetical-protein
MKRRVRLCMKDLFHQDVVEMIERETRKYQIWSIEDPSDPDFDTAYQILWDCFGPHGEMERKEAIHAFLRDDPFTPEPSGTYMRYFLLVARDADGKVRGVRDGTVLVNPAYAPDLCVIYLAHIFMIPEARGTVLSYWLRIAPVELAMQYLADLHAMGKITLPAPSAPGKYFGMNLDLAAEVEYFTPEERLSWQRILFYGRGGFDAINPRHFPYRQPDFRDPEEIRATGNQPSPFMVLVRRMGRERQAQLPIDEARALLRLLYDDFADHCAPHLLENSLQLVLDRLEERAKRKSFVELLPLPSGPKDLHRLKPLFRYNVFTKYYPESPDIRGYLNSGIREQLAANPRYLDEELARIARELEARPPYVYGSRDKSATWEGTPLAPGSEPPPPEGADAGEITRELPAPPGAATPQ
>NC_021658.1|WP_020742206.1|14556935_14559236_-|DUF2169-domain-containing-protein
MNVFAAAPVPVASILWQPSAGSWVLTVVCKATFLLRPGESPLAPDQEAPTPHDAAWDDAPSRSLQSASDLAPAKPRADVVLVGFAYAPGKAPARSLLARLAVGDLDKSIEVWCDRIFSQDGTLHEGPPFAQMPLVYERAAGGPGSWNPAGLSAGARNAYGQIAVPNLQPPGLLVSDPGKAIEPTGFGPIAPTWPSRVEKLGRHAAGWSHRDWSRKPLPAGLDPGYFNIAPPDQQLPSLREDERLVLENLHPEHPRLVTQLPGLRPTATLEGRRGGARPVPLRCDTLWIDTARGRCSLTWRAQIALEHPEEHGRVVVSLEPPQTARGEAERSVPPSSGHVAPRPPSTSQTQLPGLRSEHAPVLPWKTEERGADSAPHSSPPSGGLPFRAPATQGDLGALLAAPPARWSAPPPPAGPLDQAPAPPPPALAPLGSRGSWGTNDGPPAMVVGQSSWGTNDGPPAMTVGQKFGAAESAARASLPAPTEDDRPSRARVPPPRPAAALADDIVELLWFDPAALPRVRARWSDLILELDFEELDPRYDLPADDAAAAKDRHDVLGVLTDGSPIEPGGVPQALLASIGDRRRFTPPLVLVTGEARFPFDEVEALKATVAVVAPLAGPDKQLKDALDSIGELLKSPYLQSSTGVVDRLNQQLKELLAQSSRSLPAGQIEAHTERLLLEQRRYQTRRVLGDAWIRALLAAGGQGALPLYLPKALEHRLPLMTSLKVRVLAEAHLRQDQLEPSRYALKALALGRVFTADELRPARTSD
>NC_021658.1|WP_020742205.1|14556578_14556908_+|hypothetical-protein
MGKTASTTLAWSFKSELSQDEMLRRLEARWPSVWAISDSHHHGDYVAGKLTPEAAARIYEDGPRFVVHLRFSSAGGDVKRQLLEAQQRLIVEVLPLVGASDVWPTEPLD
>NC_021658.1|WP_148314645.1|14554968_14556567_+|PAAR-domain-containing-protein
MSALEAARMGDEIGHSSAWAGLIAGACVGLAIGGAILFSVVTGGAGAVLIGAAVAGGVGLGAGGALAGAEIGKMFEGSPCGAIATGSPDTRVEGRAAARAELDVLEHGGKKVAQGSATVFVNGKHLGRRTEKAQCGGVVSQAAVYTFIGGETLTLVPVEEEVPSWLITTLQWTALIAGGAALVLTGVGAGVVVAGLGLAGSLAGAFVGAHVGEAVGGLFGERAARVGEILGEFGGSLLGGIGAAKLGERFGWIRPPAAEEVPLGRKGPPSPEEVARARAWTDEQMAAGPAADPAAAAKLDARIAENRAAYERVQRGELEHPNTTPERLKMAVEGDADGQRVPLTYKDRAQFDRLQSDIRNVFESEGITDATVKQLGSATDGFKGNPDKPFGFWSPKSDTDFAIHSDQALVQAQQAGAPYNAKYGIFKNGEAPSALNPEGKPGLSNTSLGSKLNALAERWNVEIYGEPNPSNGGFDFKLNGPREPNGDFPTIYRGPDAVGAAPPAARPAQAGSAGTAGAGGAGVSTDPRNDGR
>NC_021658.1|WP_148314644.1|14554519_14554954_+|DcrB-related-protein
MPRYDHTDVSFDVPRDWEDRSVVVFAAPAKPGQGMISNLVMTRDTLAAGEDIRGYGDRQLVEMAQRLDGFQLYARQEITLGGQPAVEIRFAWRGQSGPIEQRLVFVGGRKPTVLSFTATMPKSEAARLNPVFDRILASVKLGQG
>NC_021658.1|WP_020742202.1|14551750_14554456_+|type-VI-secretion-system-tip-protein-VgrG
MSRLSLSFASKEESLSVRRFSVREQISSLFEVSILAVSEIEDLDLDSLVGKAAAFKAESAVLHSAVPARVWAGLCAQMEQVQVEPTGLSTYRLRIVPLLFRATLRRNSRIFQHMTIPEIVLQVLKEWEIEPEVALGAKYPAHEYRVQYGETDYAFICRLLEEAGISFYFSHRADGGRMGAELTRLVLSDAPERREPRPGAPIAYVDNPNQSSGREYVSELVVSHEVRPGHVTLRDFDFRMRPDYQLFAEARDGLEDELRYEQYHYVPGAFVVEPGKGGDTPVADDRGVARVDIKEAEALAARSLEGERGGRRSVRYRTNALDLCPGVVLSLGGHPRKELAPDQALLVVASTFEGDHSGEWTMTGEAVFAQQPYRPARRTPKPRVVGVQSAIVVGPPGEEIHTDEFGRVRAQFHWDREGRFSDASSCWIRVSQGWAGSRYGLMAIPRVGQEVLVDFFDGDPDRPVIVGRVFNSTTRVPYTLPAEKTKSGWKSDSSPGSGGFNELSFDDAAGRELIHVQAQRDYTEIIKRDQRSTVLSNRSASVTGADAVTVGGSQSVNVVRSQSHTIGEQQINQIGEGRTSIVGTSDAVDAGDSQSVTVGDGVGYTINKDKTVQITNGVASIKITPEGVFIDAQGKLEISAGGLLKLSGAEVQIDGGPNVLINTTSAKAPAVATIGKARAPSAPGRPGGGGETSAPAEVMRGGGAAEAPGGIEDVEVEGAAREVPRLDRALSSPPLTPAAAPASLQIGPAAGAAIQEAVRAPSASLAALVATGRGALELFRLAKGESLASLPSTLDVLGPVLTTPLPALGGLSAGDLGTLVNAGSAAGIFHVGGAGGQVAQFLALRTAAAPRSVNGAAVKTAAQATEASGVPAERAYAGALSAQGVALYRGDLQGGFAKVEP
>NC_021658.1|WP_020742201.1|14550695_14551706_+|GAF-domain-containing-protein
MADLNDPVRLAELHGAMLRTDADAILDACVTRAARLARAPIAFVSLVVRHIQLLRAHHGLPLELAVSCATSRSNSFCQLVVRDEAPLLVEDALRDERVPKELVEHYGIRAYAGVPVRVRGHAIGSLCVLDVVPRRFDPRTIDGLDQLAIEVAGRLSDLVERDAPVGSADLQERLVRIEQATRVLERALLSLAPVIAAAQNAAGVRQQAPVDAMHATPSALVTITSLRAAVGCWRDMGSVAEELCDEAAAVASSAPAASGLVAAARALARGMAEVGPLVRLAEGVLEGTLEETAAERGRSLVLRGAIDAHEAACVAVSEIRAGALRARAATGSGAAP
>NC_021658.1|WP_020742210.1|14564633_14566565_+|HAMP-domain-containing-protein
MDIRHRTLLSFAPLLTVAVALAVFLPLVNAALSRISAQQLALLGDLVDLQDMELAVITQRETVGQALRGFDVSPYTTDDASRRDQTLVHFNRARGERGSPQERLWQHLGAVYAELDAQHAAIFDAMQGGDAARATSVFYGEAQELTFVLLSSARAGQAQHKEALSELEARGRTLKQRALIGLAAGVGGSLLLALTFGWLLSREIVRPIERLAADAARYASGDVSGELSPAGKIKQIKHLRDAFQHLLGVTLARQDRLQQAYADVSDRAAREQQLRETVQALNEDLERAKGELERRVAERTAALRVANERLQVELAERGRAEAALKASEEQLRQLNEALEQRVVERTAELAAAQRQVLDTARRAGMAEIATNVVHNIGNVLNTVNVSAKLIAEELGGLKLEKLERAAQLLSSHREDPGRFLTEDERGRHLIAYLEALSAALEGDRRRILRYVDQLGKSVDHIKDIVRTQQTYAGATAVVEPVQLSELLEDALRMNDAALSRPHLKVVRELACPRPVYVDKHKLLQILMNLISNAKHAMDELPGREHALTLRIEARGAGRDGAVRICVQDTGVGIAKEHLTRIFSHGFTTRSGGHGFGLHSCALAAEEMSGVLSVTSDGVGRGATFTLELPVRLGSAAAERAAGP
>NC_021658.1|WP_020742211.1|14566607_14568452_-|response-regulator
MRDPRWQQNRRILLIDDNEAIHEDFRRILRSDAEASTFDSLESALFREAPGRRPVRFELTTATQGAEGLEKVREARHRGAPYALAFVDVRMPPGWDGIETLSRIWQEDGAIQAVICSAYSDYSWEEITTRFGNTDNLLILAKPFDPNEVRQMAYALTEKWNQRRALSEANHKVSAQYTVTRILVESTTLSEGILALLGALGETLGFRFAALWLGDGESGGLRCEHTWSAAPDDAAALEAATRGAQFALDAGLPGRALAQGEPTWFCDLDAVEDDPRARAARGAGLRFAVELPIAVRADAQVAAVLELMDAEPREPDPGLLDGLLAIAAKAGHFIGSKRVEAALRRSEANNRALLYAIPDTILRLGSDGVCLDFKASRESRPSLRAEDFLHRHVADVFPAGVAEQITELVGRALADEATHVFEYQEQVREGTRDYEVRIAGSDRAEAVVIVRDVTERKRAAAETEARRAREEALRAQNEMLAALSTPLIPISDDIVVMPLVGALDAQRARRVQETLVRGVASRRARVAILDITGVPRIDGQCADELLRAATAVRLLGSEVIITGLSPDVARTLVELGVDLSGIVTHNTLQHGIAEAMTSAGARGRPRRRRARRRR
>NC_021658.1|WP_044987233.1|14568544_14569843_-|type-II-secretion-system-protein-GspN
MKARLVKIAKWAAYPLFYLFCLGLFGYLTFPYDRLKDRLIAEFDRAQQKRGSGPPQRLEIDELDAYWFTGVEMKGVRLILPPNEPGSGRPTGAAAFTSTSGDAAKDSAPKPSVIEIEEAHARVKILPLLIGRMRVSFWASVFGGDVEGVVPMGKAGGDVHVEVSDVELAQVGPLGDILGLPIAGTLSANLDLSAPDGKFNKASGALEVSAKEVSVGDGKTKIQGLIALPEAKLGELVLSAEAKDGVLKVTKMSANGQDLELDGDGKVTMREPWNNSTADLYVRFKFTDAYRSKNDLTKSLLGAPGSSVPGLIEMQQPKMKRSKRSDGFYGWHVHGVLKRPRFDPHAADSPAARGRGKADSPSSAATTRKPGGMNLPLGPSEAPARDSEEQGSPPPAMPPPMPPPPSTEDESPEPRARPTPAPPAEGDPPPPE
>NC_021658.1|WP_020742212.1|14569839_14570442_-|type-II-secretion-system-protein-M
MTLRERLDKLEPRERRLLTLLVGFLGVLVFLAVPIGLASIASGRRAENQEVRDLLQQIDEASGKVSERKAQKDALLARYARPAPALAGFIEDAAKQQGLTAAESQDRPDVPHGKKYTERVTVVKMHRIGMLGLAKMLERIETSGHPVAVTKLNIKPRAGEPDSYEVELGVSAFDRKGDPQPASPAPSAPPAAEEQEEQEP
>NC_021658.1|WP_044987234.1|14570438_14571953_-|pilus-assembly-protein-PilM
MHRLLGIDAGKSVVRTALIRTSYRKVFVEALGEAPITDAVSEAEAIRAAVGLLRPDAAAIAISGEKSFYRRLDLPAAAQKEVENVLGFELEATVPFEMEDAVFDYRLLKRPPSVETLPVFAAIARADDVRERITVVKEALGFEPERVALGAVALANLEAVMPELASPSPAGASVPIALLDLDHLTSEIVILSAGEPVFARTLSRGTAGLPGTAPALARELRQTLAAWRNLGGEPLAGMYLVGGGASAQGAEVFLSTQLGLTILPLPAPRVEGLTPEQAAALPRFAKALGLALGLTPKTRGFNLRKGALEAERSYPFLREKIPILAGLGTVIALSFGFSIVAELRTLSAERELLLASLATASHDVLGEETSDPVRARELLDQGPGAADEDPMPRVDAFDVMVQLSKAVPKEITHDVLELDVNRGHVTLQGVVPSVSDAQIIADHMKEHRCFRDVKVGRTSQFTEGKHKYVLELDLKCEDKKKKKTGADAADSASAGAPEKPEGSR
>NC_021658.1|WP_020742214.1|14571980_14573483_-|general-secretion-pathway-protein-GspK
MIHPESPHAEERAAPTPPGGRARRRLRRRRDRRGVALVMVLGAITVLTVFLTELQEETSTELSAALADRDALRAEYYARSAVNLSRMLIASEPSVSQTIGPMLAIIGLKGNFQVPVWKFTDMFLGPFNAQLTEPGAAPPDEAAAAGSAAAGKNLGLTGGGRFELKIVDEDSKININRAADDVGGIADQIAVGAQLISLMSPPQYNALFEERDGDGQFSDRATICSALVDWADPGDQTFVCDTSTNAPSSTGAEDSFYQTVGLPYVRKNAPFDSFEELRLIRGMGDDFWATFVDPDPNNPDKRVLTVWGNRKQKVNVTSANAQMLLTLTCSADFVDVAATPLCTDVNQQTAFLTVASLVQSMTGGILFPTPKDFVDAMTQKAGNTLGAMLGQQLKAMGVEAVKFKPNATKALGNRSNFLSIYADGVVPGNKRETRVRIHAVIDLTGATKITDTEQNKDPAGGGGNPNPPNGGSTGAPPTPESYEQQVRSNPAGTIIYYRIE
>NC_021658.1|WP_020742215.1|14573486_14574206_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MTAAARTASSPRRRRRRAGGVTLLEVLVSVAILAIIGTLIYGAFDGMSRSRAGISRISDRYHQGRGAIARISRELQAAFLSRHQPADKNITVRLTAFTGEDSSPTDRVDFTAFAHRRLLRNAHESDQCEIGYFGSRDPERDKLDLVRREAKFIDLEPTRGGVVNVLAEDIESFDVRYLDPVTGEWVDSWDSTQPAAQFERLPSQVWVTLVLNGGPGGEPIKFETKVPIAMQVPIAFGAN
>NC_021658.1|WP_020742216.1|14574202_14574880_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MRARGFTLLEIMVAVAILGLGLTAILSAQAGAFSAAAHARNISLANGLARCKMTEIEERLARDGLPMLDEADNGPCCEGDESTSIKCSWRIEKPEMPEPKYGDLDLDTNLEGLGQLTKPAESSGSGAPSGSLDDLAQSLVGAPGGAEGGESAGGIAGLLQPFIDMLAPTLQPIFEASARRVTVRLTWQQGSQEHALELVQWVTVPQMGQPEDTGAGGGTGEGGGQ
>NC_021658.1|WP_020742217.1|14574879_14575581_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MTRRLRTRGVTLVEVLISVTVIALISGSVILGMGAVTSARLKRSAALLAGAVRVAYAHANAKSKPMRLVFDFEERMIVLEESTGELLVERNDRTGGAAAATEAEKAAVAEAEAILKGPRAPRPSFQPAKAFGFDPSSEKPGKELSSGVRFLQVETGHQDEASTEGRAYLYFWPGGQTERAAIQLSLGGEETEDSVMTVLVSPLTGKTEIRRGKVSMPRPRDDSEESEREDTGF
>NC_021658.1|WP_020742218.1|14575603_14576008_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MGRGLSRGVTLVEVLIVVTIMAIIAGGATLVLWPKLEAAKVRSAYTGASVIKTAADQYQNLGAGGEGCPTLQALVSAKQIDANKTDDPWGQPYRIKCEESEIRVYSLGKDKKEGSPDDIRDNMRQSEINKIAEM

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_021658_14	14.1|4698143|16|NC_021658|CRISPRCasFinder	4698143-4698158	16	NC_021658.1	4698184-4698199	0	1.0
NC_021658_39	39.2|9375550|17|NC_021658|CRISPRCasFinder	9375550-9375566	17	NC_021658.1	9387705-9387721	0	1.0
NC_021658_39	39.2|9375550|17|NC_021658|CRISPRCasFinder	9375550-9375566	17	NC_021658.1	9825515-9825531	0	1.0
NC_021658_60	60.1|12915004|47|NC_021658|CRISPRCasFinder	12915004-12915050	47	NC_021658.1	2165138-2165184	0	1.0
NC_021658_6	6.5|3418059|18|NC_021658|CRT	3418059-3418076	18	NC_021658.1	3769593-3769610	1	0.944
NC_021658_6	6.5|3418059|18|NC_021658|CRT	3418059-3418076	18	NC_021658.1	3776171-3776188	1	0.944
NC_021658_6	6.5|3418059|18|NC_021658|CRT	3418059-3418076	18	NC_021658.1	12531504-12531521	1	0.944
NC_021658_6	6.7|3418155|18|NC_021658|CRT	3418155-3418172	18	NC_021658.1	13976249-13976266	1	0.944
NC_021658_17	17.3|5329251|19|NC_021658|CRT	5329251-5329269	19	NC_021658.1	10598482-10598500	1	0.947
NC_021658_23	23.2|6544768|22|NC_021658|CRISPRCasFinder	6544768-6544789	22	NC_021658.1	10607772-10607793	1	0.955
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	NC_021658.1	884978-885007	1	0.967
NC_021658_45	45.1|10062112|18|NC_021658|CRT	10062112-10062129	18	NC_021658.1	10113353-10113370	1	0.944
NC_021658_45	45.1|10062112|18|NC_021658|CRT	10062112-10062129	18	NC_021658.1	13449784-13449801	1	0.944
NC_021658_45	45.4|10062238|18|NC_021658|CRT	10062238-10062255	18	NC_021658.1	3144037-3144054	1	0.944
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_021658.1	3977294-3977324	2	0.935
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_021658.1	3977303-3977333	2	0.935
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_021658.1	3977312-3977342	2	0.935
NC_021658_39	39.1|9375496|26|NC_021658|CRISPRCasFinder	9375496-9375521	26	NC_021658.1	9375577-9375602	2	0.923

1. spacer 14.1|4698143|16|NC_021658|CRISPRCasFinder matches to position: 4698184-4698199, mismatch: 0, identity: 1.0

tagaattgaaattcac	CRISPR spacer
tagaattgaaattcac	Protospacer
****************

2. spacer 39.2|9375550|17|NC_021658|CRISPRCasFinder matches to position: 9387705-9387721, mismatch: 0, identity: 1.0

tgccgccctcaccgccg	CRISPR spacer
tgccgccctcaccgccg	Protospacer
*****************

3. spacer 39.2|9375550|17|NC_021658|CRISPRCasFinder matches to position: 9825515-9825531, mismatch: 0, identity: 1.0

tgccgccctcaccgccg	CRISPR spacer
tgccgccctcaccgccg	Protospacer
*****************

4. spacer 60.1|12915004|47|NC_021658|CRISPRCasFinder matches to position: 2165138-2165184, mismatch: 0, identity: 1.0

tgaacgactacgcgctcgcgcggagctgatccgcgccctgcgtacgc	CRISPR spacer
tgaacgactacgcgctcgcgcggagctgatccgcgccctgcgtacgc	Protospacer
***********************************************

5. spacer 6.5|3418059|18|NC_021658|CRT matches to position: 3769593-3769610, mismatch: 1, identity: 0.944

ggtggaggcggcggagcc	CRISPR spacer
ggcggaggcggcggagcc	Protospacer
**.***************

6. spacer 6.5|3418059|18|NC_021658|CRT matches to position: 3776171-3776188, mismatch: 1, identity: 0.944

ggtggaggcggcggagcc	CRISPR spacer
ggcggaggcggcggagcc	Protospacer
**.***************

7. spacer 6.5|3418059|18|NC_021658|CRT matches to position: 12531504-12531521, mismatch: 1, identity: 0.944

ggtggaggcggcggagcc	CRISPR spacer
ggtggagggggcggagcc	Protospacer
******** *********

8. spacer 6.7|3418155|18|NC_021658|CRT matches to position: 13976249-13976266, mismatch: 1, identity: 0.944

cgtggaggcggcggagcc	CRISPR spacer
cgtggaggcggccgagcc	Protospacer
************ *****

9. spacer 17.3|5329251|19|NC_021658|CRT matches to position: 10598482-10598500, mismatch: 1, identity: 0.947

cgggggtgaaggcgcggag	CRISPR spacer
cgggggtgaagccgcggag	Protospacer
*********** *******

10. spacer 23.2|6544768|22|NC_021658|CRISPRCasFinder matches to position: 10607772-10607793, mismatch: 1, identity: 0.955

aggaagcgcgggcgcaggcggc	CRISPR spacer
aggaagagcgggcgcaggcggc	Protospacer
****** ***************

11. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to position: 884978-885007, mismatch: 1, identity: 0.967

gccccggagcaggtgctgcaggcgtacgcg	CRISPR spacer
gcccccgagcaggtgctgcaggcgtacgcg	Protospacer
***** ************************

12. spacer 45.1|10062112|18|NC_021658|CRT matches to position: 10113353-10113370, mismatch: 1, identity: 0.944

ccgccggagcctcccgac	CRISPR spacer
ccgccggagccgcccgac	Protospacer
*********** ******

13. spacer 45.1|10062112|18|NC_021658|CRT matches to position: 13449784-13449801, mismatch: 1, identity: 0.944

ccgccggagcctcccgac	CRISPR spacer
ccgccggagcctcacgac	Protospacer
************* ****

14. spacer 45.4|10062238|18|NC_021658|CRT matches to position: 3144037-3144054, mismatch: 1, identity: 0.944

tcaccgacgacagccagc	CRISPR spacer
tcaccggcgacagccagc	Protospacer
******.***********

15. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to position: 3977294-3977324, mismatch: 2, identity: 0.935

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcgacgcgctcgacgcgctcgacgcgctcga	Protospacer
******************** ***** ****

16. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to position: 3977303-3977333, mismatch: 2, identity: 0.935

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcgacgcgctcgacgcgctcgacgcgctcga	Protospacer
******************** ***** ****

17. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to position: 3977312-3977342, mismatch: 2, identity: 0.935

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcgacgcgctcgacgcgctcgacgcgctcga	Protospacer
******************** ***** ****

18. spacer 39.1|9375496|26|NC_021658|CRISPRCasFinder matches to position: 9375577-9375602, mismatch: 2, identity: 0.923

cctcgcccccgctccccccgaaagcg	CRISPR spacer
cctcaccgccgctccccccgaaagcg	Protospacer
****.** ******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_021658_17	17.2|5329206|19|NC_021658|CRT	5329206-5329224	19	NZ_CP010826	Thermus aquaticus Y51MC23 plasmid pTA78, complete sequence	5949-5967	0	1.0
NC_021658_23	23.2|6544768|22|NC_021658|CRISPRCasFinder	6544768-6544789	22	NZ_CP054608	Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed9, complete sequence	51478-51499	1	0.955
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	225833-225863	1	0.968
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	225833-225863	1	0.968
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	15214-15244	1	0.968
NC_021658_1	1.2|609491|23|NC_021658|CRT	609491-609513	23	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1816735-1816757	2	0.913
NC_021658_1	1.2|609491|23|NC_021658|CRT	609491-609513	23	AP021850	Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome	27061-27083	2	0.913
NC_021658_1	1.2|609491|23|NC_021658|CRT	609491-609513	23	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	437471-437493	2	0.913
NC_021658_1	1.4|609577|23|NC_021658|CRT	609577-609599	23	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1816735-1816757	2	0.913
NC_021658_1	1.4|609577|23|NC_021658|CRT	609577-609599	23	AP021850	Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome	27061-27083	2	0.913
NC_021658_1	1.4|609577|23|NC_021658|CRT	609577-609599	23	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	437471-437493	2	0.913
NC_021658_1	1.6|609663|23|NC_021658|CRT	609663-609685	23	NC_023498	Mycobacterium phage Validus, complete genome	53433-53455	2	0.913
NC_021658_10	10.6|3762890|22|NC_021658|CRT	3762890-3762911	22	MN234185	Mycobacterium phage Lemuria, complete genome	35802-35823	2	0.909
NC_021658_23	23.2|6544768|22|NC_021658|CRISPRCasFinder	6544768-6544789	22	NZ_CP044991	Deinococcus sp. AJ005 plasmid p115k, complete sequence	45510-45531	2	0.909
NC_021658_23	23.2|6544768|22|NC_021658|CRISPRCasFinder	6544768-6544789	22	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	474460-474481	2	0.909
NC_021658_23	23.2|6544768|22|NC_021658|CRISPRCasFinder	6544768-6544789	22	NZ_CP015530	Rhodococcus sp. WB1 plasmid pWB1, complete sequence	516-537	2	0.909
NC_021658_23	23.2|6544768|22|NC_021658|CRISPRCasFinder	6544768-6544789	22	NZ_CP025552	Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence	237540-237561	2	0.909
NC_021658_23	23.2|6544768|22|NC_021658|CRISPRCasFinder	6544768-6544789	22	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	226131-226152	2	0.909
NC_021658_23	23.2|6544768|22|NC_021658|CRISPRCasFinder	6544768-6544789	22	JN698994	Mycobacterium phage DS6A, complete genome	6220-6241	2	0.909
NC_021658_1	1.1|609448|23|NC_021658|CRT	609448-609470	23	NZ_CP049159	Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence	430521-430543	3	0.87
NC_021658_1	1.1|609448|23|NC_021658|CRT	609448-609470	23	NZ_CP049320	Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence	359988-360010	3	0.87
NC_021658_1	1.1|609448|23|NC_021658|CRT	609448-609470	23	MT521993	Gordonia phage RedWattleHog, complete genome	134133-134155	3	0.87
NC_021658_1	1.1|609448|23|NC_021658|CRT	609448-609470	23	MN586040	Gordonia phage Stormageddon, complete genome	135080-135102	3	0.87
NC_021658_1	1.2|609491|23|NC_021658|CRT	609491-609513	23	NZ_LR594669	Variovorax sp. SRS16 plasmid 4	277875-277897	3	0.87
NC_021658_1	1.3|609534|23|NC_021658|CRT	609534-609556	23	NZ_CP049159	Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence	430521-430543	3	0.87
NC_021658_1	1.3|609534|23|NC_021658|CRT	609534-609556	23	NZ_CP049320	Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence	359988-360010	3	0.87
NC_021658_1	1.3|609534|23|NC_021658|CRT	609534-609556	23	MT521993	Gordonia phage RedWattleHog, complete genome	134133-134155	3	0.87
NC_021658_1	1.3|609534|23|NC_021658|CRT	609534-609556	23	MN586040	Gordonia phage Stormageddon, complete genome	135080-135102	3	0.87
NC_021658_1	1.4|609577|23|NC_021658|CRT	609577-609599	23	NZ_LR594669	Variovorax sp. SRS16 plasmid 4	277875-277897	3	0.87
NC_021658_1	1.5|609620|23|NC_021658|CRT	609620-609642	23	NZ_CP049159	Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence	430521-430543	3	0.87
NC_021658_1	1.5|609620|23|NC_021658|CRT	609620-609642	23	NZ_CP049320	Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence	359988-360010	3	0.87
NC_021658_1	1.5|609620|23|NC_021658|CRT	609620-609642	23	MT521993	Gordonia phage RedWattleHog, complete genome	134133-134155	3	0.87
NC_021658_1	1.5|609620|23|NC_021658|CRT	609620-609642	23	MN586040	Gordonia phage Stormageddon, complete genome	135080-135102	3	0.87
NC_021658_10	10.3|3762764|22|NC_021658|CRT	3762764-3762785	22	NZ_CP016621	Microvirga ossetica strain V5/3m plasmid unnamed5, complete sequence	14795-14816	3	0.864
NC_021658_10	10.6|3762890|22|NC_021658|CRT	3762890-3762911	22	NZ_CP047184	Rathayibacter sp. VKM Ac-2801 plasmid unnamed, complete sequence	36127-36148	3	0.864
NC_021658_10	10.6|3762890|22|NC_021658|CRT	3762890-3762911	22	NZ_CP047181	Rathayibacter festucae strain VKM Ac-2802 plasmid unnamed1, complete sequence	31099-31120	3	0.864
NC_021658_20	20.1|5884214|25|NC_021658|CRISPRCasFinder	5884214-5884238	25	NZ_CP017947	Bosea sp. Tri-49 plasmid unnamed1, complete sequence	436927-436951	3	0.88
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	481717-481743	3	0.889
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP029358	Azospirillum sp. CFH 70021 plasmid unnamed3	256758-256784	3	0.889
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1447763-1447789	3	0.889
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1335646-1335671	4	0.846
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	CP006880	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence	522245-522270	4	0.846
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	477429-477454	4	0.846
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP022370	Bosea sp. AS-1 plasmid unnamed1, complete sequence	11042-11067	4	0.846
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NC_008712	Paenarthrobacter aurescens TC1 plasmid pTC1, complete sequence	21277-21302	4	0.846
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NC_004808	Streptomyces rochei plasmid pSLA2-L DNA, complete sequence	46497-46522	4	0.846
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_005342	Burkholderia phage Bcep43, complete genome	30636-30666	4	0.871
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	EF602154	Burkholderia phage BcepNY3, complete genome	29801-29831	4	0.871
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	AY369265	Burkholderia cenocepacia phage Bcep1, complete genome	31306-31336	4	0.871
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_004333	Burkholderia phage Bcep781, complete genome	30922-30952	4	0.871
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	AY368235	Burkholderia cepacia phage Bcep43, complete genome	30636-30666	4	0.871
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	AF543311	Burkholderia cepacia phage Bcep781, complete genome	30922-30952	4	0.871
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_005263	Burkholderia phage Bcep1, complete genome	31306-31336	4	0.871
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP013855	Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence	221043-221073	4	0.871
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3050147-3050173	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1510498-1510524	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	MH884648	Caulobacter phage Kronos, complete genome	4364-4390	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	MH744418	Streptomyces phage JustBecause, complete genome	32412-32438	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	MT310898	Streptomyces phage Kela, complete genome	32277-32303	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1119409-1119435	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1896326-1896352	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	697910-697936	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	690508-690534	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	593297-593323	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	652097-652123	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	592412-592438	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	591170-591196	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	591160-591186	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	593285-593311	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	593304-593330	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	593282-593308	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	697970-697996	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	697970-697996	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	697958-697984	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	MN234199	Mycobacterium phage Ekdilam, complete genome	24236-24262	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1250387-1250413	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1272359-1272385	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	685467-685493	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	1986385-1986411	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	437013-437039	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1761546-1761572	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1280988-1281014	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	460207-460233	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	1005709-1005735	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1425525-1425551	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	1653499-1653525	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	604470-604496	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP044082	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed4, complete sequence	42623-42649	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP031080	Paracoccus yeei strain CCUG 32053 plasmid pYEE2, complete sequence	207878-207904	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	578597-578623	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	713908-713934	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1520282-1520308	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	569608-569634	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	569608-569634	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1382224-1382250	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1456422-1456448	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1460702-1460728	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1635618-1635644	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1200832-1200858	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1380531-1380557	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1463869-1463895	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1173526-1173552	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1388417-1388443	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1385145-1385171	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1563941-1563967	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	1350633-1350659	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1475350-1475376	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1563908-1563934	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1440905-1440931	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1471257-1471283	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1562702-1562728	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1460684-1460710	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1374504-1374530	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1440905-1440931	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1471257-1471283	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1562738-1562764	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1440905-1440931	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1374526-1374552	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1440108-1440134	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1471257-1471283	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1471257-1471283	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1471257-1471283	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1562738-1562764	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1562727-1562753	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1374526-1374552	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1381468-1381494	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1362121-1362147	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1415377-1415403	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1454255-1454281	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1562727-1562753	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1374526-1374552	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1440904-1440930	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1563728-1563754	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1374526-1374552	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1374526-1374552	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1562738-1562764	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1471260-1471286	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1562749-1562775	4	0.852
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1562550-1562576	4	0.852
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	AP021851	Deinococcus grandis ATCC 43672 plasmid: pDEGR-2 DNA, complete genome	85461-85490	4	0.867
NC_021658_43	43.1|9915053|27|NC_021658|CRISPRCasFinder	9915053-9915079	27	NC_009956	Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI02, complete sequence	6981-7007	4	0.852
NC_021658_47	47.2|10090957|29|NC_021658|CRISPRCasFinder	10090957-10090985	29	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	337328-337356	4	0.862
NC_021658_48	48.1|10333345|29|NC_021658|CRISPRCasFinder	10333345-10333373	29	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	574706-574734	4	0.862
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	182838-182867	4	0.867
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1594859-1594888	4	0.867
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	537529-537558	4	0.867
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	803751-803780	4	0.867
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	109050-109079	4	0.867
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	MN062720	Microbacterium phage FuzzBuster, complete genome	25624-25653	4	0.867
NC_021658_52	52.2|11367097|25|NC_021658|CRISPRCasFinder	11367097-11367121	25	NZ_CP020539	Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence	638227-638251	4	0.84
NC_021658_52	52.2|11367097|25|NC_021658|CRISPRCasFinder	11367097-11367121	25	LN610585	Pseudomonas phage vB_PaeS_PAO1_Ab20, complete genome	18796-18820	4	0.84
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	928431-928457	4	0.852
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_CP009123	Sphingopyxis fribergensis strain Kp5.2 plasmid pSfKp5.2, complete sequence	116343-116369	4	0.852
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	282185-282211	4	0.852
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	314307-314333	4	0.852
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	580165-580191	4	0.852
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_CP035000	Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence	539992-540018	4	0.852
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP021813	Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence	921603-921628	5	0.808
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_LN831789	Streptomyces leeuwenhoekii strain type strain (C34 = DSM 42122 = NRRL B-24963) plasmid pSLE2	85433-85458	5	0.808
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP016084	Streptomyces sp. SAT1 plasmid unnamed4, complete sequence	31951-31976	5	0.808
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	24415-24440	5	0.808
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP025552	Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence	50407-50432	5	0.808
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	164697-164727	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1612651-1612681	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1395709-1395739	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	1001347-1001377	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	940258-940288	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	99957-99987	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	778601-778631	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1596835-1596865	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	9010-9040	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1141697-1141727	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	59946-59976	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	961996-962026	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1141664-1141694	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1140493-1140523	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1140506-1140536	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1140506-1140536	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	936918-936948	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1140495-1140525	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1044774-1044804	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1140495-1140525	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1069251-1069281	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1141663-1141693	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1140506-1140536	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	923143-923173	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1140517-1140547	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1140495-1140525	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	923143-923173	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1025054-1025084	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	1670501-1670531	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1099320-1099350	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1117325-1117355	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1309789-1309819	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1445662-1445692	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1018263-1018293	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1361454-1361484	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1107071-1107101	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	821925-821955	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1030681-1030711	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	932752-932782	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1027382-1027412	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	1025578-1025608	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1107060-1107090	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1112746-1112776	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1140387-1140417	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	990823-990853	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1112746-1112776	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1140387-1140417	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1112746-1112776	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	990846-990876	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1112750-1112780	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1140387-1140417	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1140387-1140417	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1140387-1140417	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	990846-990876	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1029862-1029892	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1010536-1010566	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1058483-1058513	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1104639-1104669	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	990846-990876	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1112745-1112775	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	990846-990876	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	990846-990876	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1140388-1140418	5	0.839
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022999	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence	1482315-1482345	5	0.839
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP022605	Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence	947308-947338	5	0.839
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP024895	Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence	154846-154876	5	0.839
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1430308-1430338	5	0.839
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NC_014159	Tsukamurella paurometabola DSM 20162 plasmid pTpau01, complete sequence	12064-12094	5	0.839
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	876279-876305	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2211217-2211243	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	JN698995	Mycobacterium phage Dori, complete genome	28269-28295	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP049750	Rhodococcus fascians A21d2 plasmid unnamed1	24049-24075	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NC_017966	Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence	685873-685899	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2132896-2132922	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	MN585973	Mycobacterium phage StAnnes, complete genome	24900-24926	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	MG944221	Mycobacterium phage Scowl, complete genome	29099-29125	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	MN813686	Mycobacterium phage BirdsNest, complete genome	21565-21591	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	KT309034	Mycobacterium phage Dante, complete genome	24873-24899	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NC_021538	Mycobacterium phage Job42, complete genome	26541-26567	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NC_026584	Mycobacterium phage Minerva, complete genome	38752-38778	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	813697-813723	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	449643-449669	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	813793-813819	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	469467-469493	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	813544-813570	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	813522-813548	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	LR743530	Xanthomonas phage Suba genome assembly, chromosome: 1	28393-28419	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	AP018486	Mycobacterium phage PP DNA, complete genome	36543-36569	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1697945-1697971	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1615981-1616007	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1615996-1616022	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1374768-1374794	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1615979-1616005	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP046574	Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence	382190-382216	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	527719-527745	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1617207-1617233	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	1521988-1522014	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1360337-1360363	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	1465206-1465232	5	0.815
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	MG925349	Mycobacterium phage Mendokysei, complete genome	13311-13337	5	0.815
NC_021658_43	43.1|9915053|27|NC_021658|CRISPRCasFinder	9915053-9915079	27	NC_008010	Deinococcus geothermalis DSM 11300 plasmid pDGEO01, complete sequence	316795-316821	5	0.815
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	NZ_CP010057	Hymenobacter sp. DG25B plasmid, complete sequence	56979-57008	5	0.833
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	MT121966	Pseudomonas phage SC_8_H2H8_2017 translation initiation factor IF-3, replication protein P, integrase, terminase, terminase A, capsid family protein, tail protein, and minor tail protein L genes, complete cds	29078-29107	5	0.833
NC_021658_47	47.2|10090957|29|NC_021658|CRISPRCasFinder	10090957-10090985	29	MN586020	Microbacterium phage Megan, complete genome	10967-10995	5	0.828
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MN234223	Mycobacterium phage Philly, complete genome	9649-9678	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	KP027207	Mycobacterium phage Chandler, complete genome	10522-10551	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MN096360	Mycobacterium phage Rita1961, complete genome	9760-9789	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MG839014	Mycobacterium phage RagingRooster, complete genome	9760-9789	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	KJ194581	Mycobacterium phage Audrey, complete genome	9759-9788	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	KR080203	Mycobacterium phage OrangeOswald, complete genome	9759-9788	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MH513976	Mycobacterium phage Morty007, complete genome	10549-10578	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MH051265	Mycobacterium phage Yahalom, complete genome	9760-9789	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MH316565	Mycobacterium phage Mortcellus, complete genome	10397-10426	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MT310871	Mycobacterium phage Jackstina, complete genome	9676-9705	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MK359357	Mycobacterium phage RomaT, complete genome	10522-10551	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	JF704095	Mycobacterium phage Daisy, complete sequence	9762-9791	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	EU816589	Mycobacterium phage Phaedrus, complete genome	9676-9705	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MN096359	Mycobacterium phage Obutu, complete genome	9760-9789	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MK061414	Mycobacterium phage Marley1013, complete genome	10549-10578	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MT952851	Mycobacterium phage Gervas, complete genome	9748-9777	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MG925353	Mycobacterium phage Nozo, complete genome	10524-10553	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	KJ194584	Mycobacterium phage Heathcliff, complete genome	9745-9774	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MN444872	Mycobacterium phage SynergyX, complete genome	9760-9789	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MH576977	Mycobacterium phage Tydolla, complete genome	10521-10550	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MG925338	Mycobacterium phage ChaChing, complete genome	9774-9803	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NC_023742	Mycobacterium phage Akoma, complete genome	9759-9788	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MG920059	Mycobacterium phage Baloo, complete genome	9759-9788	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NC_023686	Mycobacterium phage Gadjet, complete genome	9763-9792	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	KR080205	Mycobacterium phage Corofin, complete genome	9784-9813	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NC_041965	Mycobacterium phage Athena, complete genome	10522-10551	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	DQ398049	Mycobacterium phage Pipefish, complete genome	10645-10674	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	KF493879	Mycobacterium phage Bernardo, complete genome	9781-9810	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MT310892	Mycobacterium phage Compostia, complete genome	9767-9796	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	JN699018	Mycobacterium phage Kamiyu, complete genome	9754-9783	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NC_012027	Mycobacterium phage Phlyer, complete genome	10516-10545	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MN444873	Mycobacterium phage Abinghost, complete genome	9759-9788	5	0.833
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP029835	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed5, complete sequence	236760-236789	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	897564-897593	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	338227-338256	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015369	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p2, complete sequence	42490-42519	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP046100	Rhodococcus sp. AQ5-07 plasmid unnamed1, complete sequence	133835-133864	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_013859	Azospirillum sp. B510 plasmid pAB510e, complete sequence	427152-427181	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP054620	Azospirillum oryzae strain KACC 14407 plasmid unnamed5, complete sequence	183677-183706	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP011771	Croceicoccus naphthovorans strain PQ-2 plasmid p1, complete sequence	32619-32648	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP016453	Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence	726380-726409	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_028980	Pseudomonas phage PAE1, complete genome	6788-6817	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP009292	Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence	140685-140714	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP047145	Streptomyces sp. HF10 plasmid plas1, complete sequence	54343-54372	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP017244	Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence	1974115-1974144	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021027	Rhizobium sp. TAL182 plasmid pRetTAL182c, complete sequence	92301-92330	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP014508	Burkholderia sp. PAMC 28687 plasmid 1, complete sequence	2139-2168	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP013561	Rhizobium phaseoli strain N841 plasmid pRphaN841d, complete sequence	104614-104643	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_008761	Polaromonas naphthalenivorans CJ2 plasmid pPNAP05, complete sequence	57798-57827	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021125	Rhizobium sp. Kim5 plasmid pRetKim5a, complete sequence	103208-103237	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP013514	Rhizobium sp. N1314 plasmid pRspN1314c, complete sequence	104613-104642	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	132527-132556	5	0.833
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP010860	Marinovum algicola DG 898 plasmid pMaD5, complete sequence	115211-115240	5	0.833
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_LR134469	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence	60705-60731	5	0.815
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NC_019957	Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence	241399-241425	5	0.815
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_LR134454	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence	19937-19963	5	0.815
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NC_017324	Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence	45638-45663	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP021819	Sinorhizobium meliloti strain M162 plasmid psymA, complete sequence	850985-851010	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	1286544-1286569	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP021805	Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence	1414431-1414456	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	1371214-1371239	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	497387-497412	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP045223	Achromobacter xylosoxidans strain DN002 plasmid unnamed	80722-80747	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	522021-522046	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	444084-444109	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	400013-400038	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	934299-934324	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	900638-900663	6	0.769
NC_021658_4	4.1|2183523|26|NC_021658|CRISPRCasFinder	2183523-2183548	26	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	82304-82329	6	0.769
NC_021658_8	8.1|3493336|35|NC_021658|CRISPRCasFinder	3493336-3493370	35	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	939326-939360	6	0.829
NC_021658_8	8.1|3493336|35|NC_021658|CRISPRCasFinder	3493336-3493370	35	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	873794-873828	6	0.829
NC_021658_8	8.1|3493336|35|NC_021658|CRISPRCasFinder	3493336-3493370	35	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1577607-1577641	6	0.829
NC_021658_26	26.1|7538323|34|NC_021658|CRISPRCasFinder	7538323-7538356	34	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	31948-31981	6	0.824
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1113123-1113153	6	0.806
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NZ_CP010957	Sphingobium sp. YBL2 plasmid 3pYBL2-3, complete sequence	270329-270359	6	0.806
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	982958-982988	6	0.806
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	400471-400501	6	0.806
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP016082	Streptomyces sp. SAT1 plasmid unnamed2, complete sequence	103356-103386	6	0.806
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_LR134467	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence	97649-97679	6	0.806
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_LR594691	Variovorax sp. WDL1 plasmid 3	91190-91220	6	0.806
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1861649-1861679	6	0.806
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP009572	Sphingomonas taxi strain ATCC 55669 plasmid STP1, complete sequence	151784-151814	6	0.806
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP022371	Bosea sp. AS-1 plasmid unnamed2, complete sequence	100363-100393	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP013855	Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence	220899-220929	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1728824-1728854	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	MK494124	Mycobacterium phage Kristoff, complete genome	2455-2485	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	MN586038	Mycobacterium phage WalterMcMickey, complete genome	2289-2319	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	JX411619	Mycobacterium virus Rebeuca, complete genome	2456-2486	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NC_041982	Mycobacterium phage Twister, complete genome	2289-2319	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1007834-1007864	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	609564-609594	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	266820-266850	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1416830-1416860	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1472978-1473008	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1401482-1401512	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1383668-1383698	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1383659-1383689	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1416976-1417006	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1416957-1416987	6	0.806
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1416942-1416972	6	0.806
NC_021658_35	35.1|9128365|27|NC_021658|CRISPRCasFinder	9128365-9128391	27	NZ_CP032928	Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence	419373-419399	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3466909-3466935	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP007144	Hymenobacter swuensis DY53 plasmid pHsw1, complete sequence	211354-211380	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP036456	Streptomonospora sp. M2 plasmid phiM2, complete sequence	66888-66914	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP020443	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed3, complete sequence	17649-17675	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	2089051-2089077	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1017909-1017935	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP044079	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence	342041-342067	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_KJ599675	Micrococcus sp. A7 plasmid pLMA7, complete sequence	10596-10622	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_KR152226	Micrococcus sp. MG-2010-D12 plasmid pJD12, complete sequence	2536-2562	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NC_024972	Micrococcus sp. A1 plasmid pLMA1, complete sequence	8261-8287	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	AF428260	Propionibacterium phage phiB5, complete genome	2504-2530	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NC_003460	Propionibacterium phage B5, complete genome	2504-2530	6	0.778
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NC_023692	Mycobacterium phage BigNuz, complete genome	21026-21052	6	0.778
NC_021658_41	41.1|9547674|30|NC_021658|CRISPRCasFinder	9547674-9547703	30	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	153908-153937	6	0.8
NC_021658_41	41.1|9547674|30|NC_021658|CRISPRCasFinder	9547674-9547703	30	NC_007960	Nitrobacter hamburgensis X14 plasmid 2, complete sequence	58822-58851	6	0.8
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	NC_031255	Gordonia phage Schwabeltier, complete genome	37918-37947	6	0.8
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2243376-2243405	6	0.8
NC_021658_43	43.1|9915053|27|NC_021658|CRISPRCasFinder	9915053-9915079	27	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	401037-401063	6	0.778
NC_021658_47	47.2|10090957|29|NC_021658|CRISPRCasFinder	10090957-10090985	29	NZ_CP017942	Phyllobacterium zundukense strain Tri-48 plasmid unnamed3, complete sequence	357649-357677	6	0.793
NC_021658_47	47.2|10090957|29|NC_021658|CRISPRCasFinder	10090957-10090985	29	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	9234-9262	6	0.793
NC_021658_47	47.2|10090957|29|NC_021658|CRISPRCasFinder	10090957-10090985	29	NZ_LN997849	Magnetospirillum sp. XM-1 isolate XM1 plasmid II, complete sequence	99160-99188	6	0.793
NC_021658_47	47.2|10090957|29|NC_021658|CRISPRCasFinder	10090957-10090985	29	NC_010399	Clavibacter michiganensis subsp. sepedonicus plasmid pCS1, complete sequence	38307-38335	6	0.793
NC_021658_47	47.2|10090957|29|NC_021658|CRISPRCasFinder	10090957-10090985	29	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	360683-360711	6	0.793
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	25726-25755	6	0.8
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NC_013449	Streptomyces sp. W9 plasmid pCQ3, complete sequence	23697-23726	6	0.8
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	JF412299	EBPR siphovirus 4, partial sequence	6500-6529	6	0.8
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	KT021004	Thermobifida phage P1312, complete genome	43510-43539	6	0.8
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	232027-232056	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	972279-972308	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	357514-357543	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1389209-1389238	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LR134455	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 13, complete sequence	107318-107347	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	56792-56821	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1360127-1360156	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	382989-383018	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	172222-172251	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP032704	Pantoea dispersa strain DSM 32899 plasmid unnamed2, complete sequence	37208-37237	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_015223	Nitrosomonas sp. AL212 plasmid pNAL21201, complete sequence	14911-14940	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	453132-453161	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	675829-675858	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	675838-675867	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	746183-746212	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP023551	Rhodobacter sp. CZR27 plasmid unnamed3, complete sequence	37642-37671	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	695137-695166	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	661855-661884	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP031079	Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence	336389-336418	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	1392524-1392553	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP024426	Paracoccus yeei strain TT13 plasmid pTT13-4, complete sequence	131306-131335	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP020445	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed5, complete sequence	71080-71109	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP048283	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248c, complete sequence	148162-148191	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021126	Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence	278950-278979	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1536253-1536282	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP044079	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence	84961-84990	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	38506-38535	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	KT381864	Thiobacimonas phage vB_ThpS-P1, complete genome	11594-11623	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_009806	Kineococcus radiotolerans SRS30216 = ATCC BAA-149 plasmid pKRAD01, complete sequence	144830-144859	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP029777	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence	166477-166506	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_011143	Phenylobacterium zucineum HLK1 plasmid, complete sequence	155109-155138	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_011371	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG204, complete sequence	208248-208277	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	310610-310639	6	0.8
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	836480-836509	6	0.8
NC_021658_58	58.1|12836862|31|NC_021658|CRISPRCasFinder	12836862-12836892	31	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	45649-45679	6	0.806
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	179600-179626	6	0.778
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1242554-1242580	6	0.778
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_CP018080	Sulfitobacter sp. AM1-D1 plasmid unnamed4, complete sequence	94584-94610	6	0.778
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_KY349138	Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_2, complete sequence	156133-156159	6	0.778
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1951420-1951446	6	0.778
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NC_042348	Salinibacter virus M1EM-1, partial genome	12274-12300	6	0.778
NC_021658_7	7.1|3465111|32|NC_021658|CRISPRCasFinder	3465111-3465142	32	NZ_CP017944	Phyllobacterium zundukense strain Tri-48 plasmid unnamed4, complete sequence	107641-107672	7	0.781
NC_021658_8	8.1|3493336|35|NC_021658|CRISPRCasFinder	3493336-3493370	35	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	48787-48821	7	0.8
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1650828-1650858	7	0.774
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NC_008738	Marinobacter hydrocarbonoclasticus VT8 plasmid pMAQU01, complete sequence	37263-37293	7	0.774
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NC_019917	Burkholderia phage BcepMigl, complete genome	32461-32491	7	0.774
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NC_005262	Burkholderia cepacia phage Bcep22, complete genome	33597-33627	7	0.774
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	398380-398410	7	0.774
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	522337-522367	7	0.774
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1466456-1466486	7	0.774
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	346612-346642	7	0.774
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_LR134459	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence	99909-99939	7	0.774
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	138423-138453	7	0.774
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_LR134455	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 13, complete sequence	95645-95675	7	0.774
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1186984-1187014	7	0.774
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP048816	Caulobacter rhizosphaerae strain KCTC 52515 plasmid unnamed	168374-168404	7	0.774
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1088779-1088809	7	0.774
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1221964-1221994	7	0.774
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP024772	Bacillus thuringiensis LM1212 plasmid pLM1, complete sequence	236763-236793	7	0.774
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	485054-485084	7	0.774
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	732234-732264	7	0.774
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NC_018836	Streptomyces phage phiHau3, complete genome	18194-18224	7	0.774
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	161260-161290	7	0.774
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NC_015952	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence	54572-54602	7	0.774
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	781179-781209	7	0.774
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	481558-481584	7	0.741
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	186135-186161	7	0.741
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	CU468217	Azospirillum brasilense bacteriophage Cd, complete genome	10214-10240	7	0.741
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NC_010355	Azospirillum phage Cd, complete genome	10214-10240	7	0.741
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	578720-578746	7	0.741
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP033323	Azospirillum brasilense strain Cd plasmid p5, complete sequence	166511-166537	7	0.741
NC_021658_36	36.3|9128860|27|NC_021658|CRISPRCasFinder	9128860-9128886	27	NZ_CP033317	Azospirillum brasilense strain Sp 7 plasmid p5, complete sequence	173026-173052	7	0.741
NC_021658_37	37.29|9169427|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9169427-9169462	36	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1057543-1057578	7	0.806
NC_021658_41	41.1|9547674|30|NC_021658|CRISPRCasFinder	9547674-9547703	30	MN585986	Microbacterium phage Ariadne, complete genome	22698-22727	7	0.767
NC_021658_41	41.1|9547674|30|NC_021658|CRISPRCasFinder	9547674-9547703	30	MN586007	Microbacterium phage Smarties, complete genome	22698-22727	7	0.767
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	110630-110659	7	0.767
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	335841-335870	7	0.767
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	MT310853	Microbacterium phage AvGardian, complete genome	31609-31638	7	0.767
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	LR134122	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2	341573-341602	7	0.767
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	FJ706172	Propionibacterium phage PAS50, complete genome	13102-13131	7	0.767
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	NC_015453	Propionibacterium phage PAS50 endogenous virus, complete genome	13102-13131	7	0.767
NC_021658_47	47.2|10090957|29|NC_021658|CRISPRCasFinder	10090957-10090985	29	NZ_CP015372	Pandoraea pnomenusa strain MCB032 plasmid unnamed 1, complete sequence	9899-9927	7	0.759
NC_021658_47	47.2|10090957|29|NC_021658|CRISPRCasFinder	10090957-10090985	29	NZ_CP015372	Pandoraea pnomenusa strain MCB032 plasmid unnamed 1, complete sequence	121233-121261	7	0.759
NC_021658_47	47.2|10090957|29|NC_021658|CRISPRCasFinder	10090957-10090985	29	NZ_CP045095	Streptomyces sp. GY16 plasmid unnamed1, complete sequence	19809-19837	7	0.759
NC_021658_48	48.1|10333345|29|NC_021658|CRISPRCasFinder	10333345-10333373	29	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	195034-195062	7	0.759
NC_021658_50	50.1|10765981|30|NC_021658|CRT	10765981-10766010	30	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	398657-398686	7	0.767
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP034352	Streptomyces sp. W1SF4 plasmid p2, complete sequence	6263-6292	7	0.767
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	MK113950	Phage 5P_2, complete genome	57154-57183	7	0.767
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP031754	Rhodobacter sphaeroides strain EBL0706 plasmid p.C, complete sequence	39155-39184	7	0.767
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	GQ919031	Streptomyces phage ZL12, complete genome	33086-33115	7	0.767
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	MN204498	Streptomyces phage Saftant, complete genome	11053-11082	7	0.767
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP021408	Celeribacter manganoxidans strain DY25 plasmid pDY25-D, complete sequence	4339-4368	7	0.767
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	438144-438173	7	0.767
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	816855-816884	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	143420-143449	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	128824-128853	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP034911	Ensifer alkalisoli strain YIC4027 plasmid unnamed, complete sequence	288034-288063	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015737	Shinella sp. HZN7 plasmid pShin-01, complete sequence	76909-76938	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP013426	Burkholderia sp. MSMB0856 plasmid pMSMB0856, complete sequence	75823-75852	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	455962-455991	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	LR134122	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2	203226-203255	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	LR134122	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2	296373-296402	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	455996-456025	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	455996-456025	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	455988-456017	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP013855	Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence	230501-230530	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	334550-334579	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	422541-422570	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1542512-1542541	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	334559-334588	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	410864-410893	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	437873-437902	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	222519-222548	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	422541-422570	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1661737-1661766	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	422553-422582	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	422574-422603	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	422540-422569	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1661683-1661712	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP054618	Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence	393492-393521	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	1653256-1653285	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP050991	Chromobacterium violaceum strain FDAARGOS_635 plasmid unnamed, complete sequence	98-127	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	1592552-1592581	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	881498-881527	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	MH669000	Gordonia phage Ali17, complete genome	5705-5734	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	MN586026	Gordonia phage Leonard, complete genome	6357-6386	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_031112	Gordonia phage Phinally, complete genome	6354-6383	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP013072	Sphingobium indicum B90A plasmid pSRL2, complete sequence	23924-23953	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP018096	Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence	226008-226037	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_AP021845	Azospira sp. I09 plasmid pAZI09, complete sequence	35811-35840	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP024423	Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence	162397-162426	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	358542-358571	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	507597-507626	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	349459-349488	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	21750-21779	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	606755-606784	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	356187-356216	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP044080	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence	141891-141920	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_014035	Rhodobacter capsulatus SB 1003 plasmid pRCB133, complete sequence	61239-61268	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KX518743	Escherichia coli strain HYEC7 plasmid pHYEC7-IncHI2, complete sequence	77232-77261	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KY019259	Escherichia coli strain YJMC8 plasmid pHNYJC8, complete sequence	77051-77080	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	AP018456	Escherichia coli O25b:H4-ST131 plasmid pMRY09-581ECO_1 MRY09-581 DNA, complete sequence	31779-31808	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	151977-152006	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP019604	Croceicoccus marinus strain E4A9 plasmid pCME4A9II, complete sequence	200986-201015	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP026492	Escherichia coli strain HS13-1 plasmid pHS13-1-IncHI2, complete sequence	260469-260498	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP033514	Vibrio cholerae strain E4 plasmid pVCR94, complete sequence	123925-123954	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KT988018	Escherichia coli strain V282 plasmid pEcoV282, complete sequence	102864-102893	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KX421096	Salmonella enterica subsp. enterica serovar Indiana strain A3 plasmid pA3T, complete sequence	79008-79037	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KU341381	Escherichia coli strain SHP45 plasmid pHNSHP45-2, complete sequence	77050-77079	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KY019258	Escherichia coli strain LDHF400 plasmid pHNLDF400, complete sequence	77050-77079	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KT282968	Escherichia coli strain EC012 plasmid pEC012, complete sequence	26269-26298	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KX721511	Salmonella enterica subsp. enterica serovar Typhimurium strain SC523 plasmid pSC523, complete sequence	136761-136790	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KU043115	Escherichia coli strain Y5 plasmid pECY55, complete sequence	57757-57786	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KX254341	Escherichia coli strain JS-B60 plasmid pECJS-B60-267, complete sequence	78421-78450	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1596463-1596492	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015077	Escherichia coli strain Ecol_448 plasmid pEC448_1, complete sequence	50856-50885	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP035548	Salmonella enterica subsp. enterica serovar Typhimurium strain YU07-18 plasmid pYU07-18_IncA/C2, complete sequence	112553-112582	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KP453775	Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence	231726-231755	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KT334335	Salmonella enterica subsp. enterica serovar Typhimurium strain ST06-53 plasmid pHK0653, complete sequence	77038-77067	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_KT990220	Escherichia coli strain 42-2 plasmid p42-2, complete sequence	47542-47571	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP041338	Escherichia coli strain CCUG 73778 plasmid pSUH-1, complete sequence	56224-56253	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP023850	Escherichia coli strain 4/0 plasmid p4_0.1, complete sequence	93000-93029	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP035517	Escherichia coli strain U14A plasmid pU14A_A, complete sequence	75573-75602	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP048368	Escherichia coli strain 163 plasmid pC-F-164_A-OXA140, complete sequence	40808-40837	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	457344-457373	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LR130565	Escherichia coli strain MS14387 isolate MS14387 plasmid 2	31738-31767	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP042337	Escherichia coli strain GZ04-0086 plasmid pCTXM-GZ04, complete sequence	28655-28684	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1662023-1662052	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	479580-479609	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	469986-470015	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP035478	Escherichia coli strain U13A plasmid pU13A_A, complete sequence	119614-119643	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP014493	Escherichia coli strain MVAST0167 plasmid pMVAST0167_1, complete sequence	101063-101092	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	LR606150	Rhizobium sp. Q54 genome assembly, plasmid: 7	122098-122127	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP048331	Escherichia coli strain 10 plasmid p010_A, complete sequence	20615-20644	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	KY075659	Escherichia coli strain GD80 plasmid pGD80-2, complete sequence	78544-78573	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP011136	Escherichia coli VR50 plasmid pVR50B, complete sequence	60724-60753	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	LN850163	Escherichia coli plasmid pI1-34TF, strain I1-34	153211-153240	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021289	Escherichia coli strain PA45B plasmid pPA45B, complete sequence	20269-20298	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP029575	Escherichia coli strain DA33133 plasmid pDA33133-157, complete sequence	67373-67402	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP019282	Escherichia coli strain 13P484A plasmid p13P484A-2, complete sequence	28490-28519	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	MN007141	Escherichia coli strain 91 plasmid p91_NDM5, complete sequence	38962-38991	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LS992181	Escherichia coli isolate Escherichia coli str. TO124 plasmid 2, complete sequence	62554-62583	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LR130556	Escherichia coli strain MS14385 isolate MS14385 plasmid 2	20615-20644	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP014496	Escherichia coli strain SaT040 plasmid pSaT040, complete sequence	20640-20669	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP013836	Escherichia coli strain JJ1897 plasmid pJJ1897_1, complete sequence	90902-90931	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP011515	Mitsuaria sp. 7 plasmid, complete sequence	51514-51543	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP019251	Escherichia coli strain 13KWH46 plasmid p13KWH46-1, complete sequence	43165-43194	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021728	Escherichia coli strain Combat11I9 plasmid pCombat11I9-2, complete sequence	34764-34793	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP006642	Escherichia coli PCN061 plasmid PCN061p6, complete sequence	38735-38764	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	209082-209111	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	1612215-1612244	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	1059634-1059663	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	1476583-1476612	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	MT077880	Escherichia coli plasmid p1, complete sequence	27331-27360	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1697224-1697253	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1711864-1711893	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP041619	Shigella flexneri strain C32 plasmid pC32_1, complete sequence	41498-41527	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP030770	Escherichia coli strain 2017C-4173W12 plasmid p2017C-4173W12, complete sequence	124238-124267	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP019247	Escherichia coli strain Combat13F7 plasmid pCombat13F7-2, complete sequence	28275-28304	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP019268	Escherichia coli strain 13C1079T plasmid p13C1079T-1, complete sequence	34392-34421	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP019262	Escherichia coli strain 13C1065T plasmid p13C1065T-3, complete sequence	134272-134301	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP019244	Escherichia coli strain Combat2C1 plasmid pCombat2C1-1, complete sequence	10209-10238	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP012634	Escherichia coli strain SF-166 plasmid pSF-166-1, complete sequence	19784-19813	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP036244	Escherichia coli strain S65EC plasmid pS65EC, complete sequence	112664-112693	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP024718	Escherichia coli strain LS4 plasmid p1LS4, complete sequence	38755-38784	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP023845	Escherichia coli strain 4/1-1 plasmid p4_1_1.1, complete sequence	56587-56616	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	MN577015	Salmonella enterica plasmid p0085-NDM, complete sequence	152455-152484	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	MN086777	Escherichia coli plasmid p16EC-p0111, complete sequence	52069-52098	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP024721	Escherichia coli isolate NQ3 plasmid p1NQ3, complete sequence	15573-15602	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015160	Escherichia coli strain Eco889 plasmid pECO-fce, complete sequence	32092-32121	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP027130	Escherichia coli strain AR_0372 plasmid unnamed1, complete sequence	21046-21075	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP014523	Escherichia coli strain ZH063 plasmid pZH063_1, complete sequence	103356-103385	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP029580	Escherichia coli strain DA33137 plasmid pDA33137-178, complete sequence	74789-74818	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP014498	Escherichia coli strain ZH193 plasmid pZH193, complete sequence	114182-114211	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	474240-474269	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP032877	Escherichia coli strain WCHEC000837 plasmid pCTXM15_000837, complete sequence	100747-100776	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_008270	Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence	227066-227095	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP053232	Escherichia coli strain SCU-306 plasmid pSCU-306-1, complete sequence	68177-68206	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP053248	Escherichia coli strain SCU-482 plasmid pSCU-482-1, complete sequence	31750-31779	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP053246	Escherichia coli strain SCU-485 plasmid pSCU-485-1, complete sequence	31776-31805	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP027119	Escherichia coli strain 26561 plasmid unnamed1, complete sequence	68806-68835	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015740	Shinella sp. HZN7 plasmid pShin-04, complete sequence	102579-102608	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP038139	Escherichia coli strain G3X16-2 plasmid pG3X16-2-2, complete sequence	158467-158496	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP034820	Salmonella sp. SSDFZ54 plasmid pTB501, complete sequence	140057-140086	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	524327-524356	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP010882	Escherichia coli strain MNCRE44 plasmid pMNCRE44_6, complete sequence	110102-110131	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015131	Klebsiella pneumoniae strain Kpn555 plasmid pKPN-7c3, complete sequence	85339-85368	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP041177	Salmonella enterica subsp. enterica serovar Enteritidis strain SJTUF12367v2 plasmid p12367A, complete sequence	87339-87368	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1662160-1662189	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	334607-334636	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LT985252	Escherichia coli strain 666 plasmid RCS51_p, complete sequence	58779-58808	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP050707	Salmonella enterica subsp. enterica serovar Enteritidis strain SE124 plasmid pSE124-1, complete sequence	25854-25883	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	625457-625486	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	127364-127393	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP035468	Escherichia coli strain U12A plasmid pU12A_A, complete sequence	119614-119643	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP051707	Escherichia coli strain SCU-124 plasmid pSCU-124-1, complete sequence	34177-34206	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LR130563	Escherichia coli strain MS14384 isolate MS14384 plasmid 2	34172-34201	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP051701	Escherichia coli strain SCU-125 plasmid pSCU-125-1, complete sequence	39937-39966	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	841110-841139	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP051712	Escherichia coli strain SCU-123 plasmid pSCU-123-1, complete sequence	34172-34201	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP051695	Escherichia coli strain SCU-313 plasmid pSCU-313-1, complete sequence	20616-20645	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP051726	Escherichia coli strain SCU-112 plasmid pSCU-112-1, complete sequence	30141-30170	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021690	Escherichia coli strain AR_0058 plasmid tig00007555j7554, complete sequence	83157-83186	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP024860	Escherichia coli strain AR_0014 plasmid unitig_1_pilon, complete sequence	72842-72871	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP024816	Escherichia coli strain CREC-629 plasmid pCREC-629_1, complete sequence	18414-18443	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP034832	Salmonella sp. SSDFZ69 plasmid pTB601, complete sequence	76281-76310	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	478053-478082	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP024153	Escherichia coli strain 14EC033 plasmid p14EC033f, complete sequence	64712-64741	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP051736	Escherichia coli strain SCU-108 plasmid pSCU-108-1, complete sequence	34172-34201	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP051715	Escherichia coli strain SCU-122 plasmid pSCU-122-1, complete sequence	34172-34201	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP033353	Salmonella enterica subsp. enterica strain CFSA664 plasmid pCFSA664-1, complete sequence	22433-22462	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	185384-185413	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP029113	Escherichia coli strain AR435 plasmid unnamed1, complete sequence	85038-85067	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_AP022566	Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence	211278-211307	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP042879	Escherichia coli strain NMBU_W05E18 plasmid pNMBU-W05E18_01, complete sequence	50472-50501	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	1470346-1470375	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	CP054458	Escherichia coli strain SCU-103 plasmid pSCU-103-1, complete sequence	17574-17603	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	704123-704152	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	475502-475531	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	734919-734948	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	1705295-1705324	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LT795115	Salmonella enterica subsp. enterica serovar Typhimurium isolate VNB151-sc-2315230 plasmid p1	46831-46860	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP024130	Escherichia coli strain 14EC001 plasmid p14EC001c, complete sequence	37499-37528	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP011429	Salmonella enterica subsp. enterica serovar Typhimurium strain YU39 isolate YUHS 05-78 plasmid pYU39_IncA/C, complete sequence	122735-122764	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP016498	Escherichia coli strain UPEC 26-1 plasmid unnamed1, complete sequence	43951-43980	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	CP054382	Escherichia coli strain SCU-175 plasmid pSCU-175-3, complete sequence	27603-27632	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021355	Rhodococcus sp. S2-17 plasmid pRB98, complete sequence	719006-719035	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP043407	Escherichia coli strain NMBU-W13E19 plasmid pNMBU-W13E19_01, complete sequence	12577-12606	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	CP054450	Escherichia coli strain SCU-488 plasmid pSCU-488-1, complete sequence	92352-92381	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_017630	Escherichia coli UM146 plasmid pUM146, complete sequence	102165-102194	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	486976-487005	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	471410-471439	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	368339-368368	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP048648	Escherichia coli strain GW-AmxH19 plasmid unnamed, complete sequence	34613-34642	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP023550	Rhodobacter sp. CZR27 plasmid unnamed2, complete sequence	7164-7193	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP025677	Escherichia albertii strain ChinaSP140150 plasmid pEA-1, complete sequence	90501-90530	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	AP022368	Escherichia coli E318 plasmid pE318_IMP6 DNA, complete sequence	20615-20644	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	470501-470530	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	MN822124	Escherichia coli strain 14E509 plasmid p14E509-1FII, complete sequence	101904-101933	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_HG941719	Escherichia coli O25b:H4-ST131 strain EC958 plasmid pEC958, complete sequence	78663-78692	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	489255-489284	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP025708	Escherichia coli strain YDC107 plasmid pYDC107_184, complete sequence	20615-20644	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP006369	Aureimonas sp. AU20 plasmid pAU20b, complete sequence	43817-43846	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021871	Escherichia coli strain H105 plasmid pH105, complete sequence	21100-21129	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	AP022363	Escherichia coli E303 plasmid pE303_IMP6 DNA, complete sequence	20615-20644	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015914	Escherichia coli strain 210205630 isolate 210205630 plasmid pSLy2, complete sequence	124699-124728	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	MN823989	Klebsiella pneumoniae strain 283149 plasmid p283149-FII, complete sequence	64294-64323	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052879	Escherichia coli strain C21 plasmid pC21-2, complete sequence	9450-9479	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	AP022361	Escherichia coli E301 plasmid pE301_IMP6 DNA, complete sequence	20615-20644	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	467526-467555	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	554232-554261	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	MF353155	Escherichia coli plasmid pLZ135-CTX, complete sequence	46217-46246	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	471152-471181	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	475519-475548	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP050710	Salmonella enterica subsp. enterica serovar Enteritidis strain SE109 plasmid pSE109-1, complete sequence	28291-28320	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	489255-489284	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	488762-488791	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	471225-471254	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	489255-489284	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	AP023228	Escherichia coli YJ3 plasmid pYJ3-a DNA, complete genome	149315-149344	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP014110	Escherichia coli strain FDAARGOS_144 plasmid unnamed1, complete sequence	79950-79979	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021937	Escherichia coli strain AR_0055 plasmid unitig_3j3rc_linear, complete sequence	115609-115638	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021937	Escherichia coli strain AR_0055 plasmid unitig_3j3rc_linear, complete sequence	35471-35500	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP033632	Escherichia coli isolate ECCNB12-2 plasmid pTB-nb1, complete sequence	99248-99277	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_008703	Mycobacterium sp. KMS plasmid pMKMS01, complete sequence	62325-62354	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP050724	Salmonella enterica subsp. enterica serovar Enteritidis strain SE74 plasmid pSE74-1, complete sequence	53172-53201	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	524365-524394	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	468542-468571	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	488762-488791	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	471225-471254	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP048026	Escherichia coli strain GZEC065 plasmid pTEM1-GZEC065, complete sequence	40024-40053	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP020117	Escherichia coli strain AR_0104 plasmid unitig_5, complete sequence	75426-75455	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	CP054321	Escherichia coli strain SCU-390 plasmid pSCU-390-1, complete sequence	8723-8752	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP027703	Escherichia coli strain 675SK2 plasmid p675SK2_B, complete sequence	34146-34175	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP041629	Escherichia coli strain PE15 plasmid pPE15-IncF, complete sequence	12570-12599	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	LC520285	Escherichia coli HP030 plasmid pHP030 DNA, complete sequence	31779-31808	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	LC520287	Escherichia coli HP129 plasmid pHP129 DNA, complete sequence	31779-31808	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	LC520288	Escherichia coli HP223 plasmid pHP223 DNA, complete sequence	31779-31808	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022581	Gordonia rubripertincta strain CWB2 plasmid pGCWB2, complete sequence	59236-59265	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	489255-489284	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	488762-488791	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_013951	Klebsiella pneumoniae plasmid pKF3-140, complete sequence	26355-26384	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP051224	Escherichia coli strain SCZE5 plasmid pSCZE2	60676-60705	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	LC520269	Escherichia coli A0084 plasmid pA0084 DNA, complete sequence	31769-31798	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	LC520270	Escherichia coli A0086 plasmid pA0086 DNA, complete sequence	31779-31808	7	0.767
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	LC520271	Escherichia coli A0140 plasmid pA0140 DNA, complete sequence	31762-31791	7	0.767
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NC_007412	Trichormus variabilis ATCC 29413 plasmid C, complete sequence	167679-167705	7	0.741
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NC_005241	Cupriavidus necator H16 megaplasmid pHG1, complete sequence	60641-60667	7	0.741
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_CP039289	Cupriavidus necator H16 plasmid pHG1, complete sequence	60641-60667	7	0.741
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_CP047244	Trichormus variabilis 0441 plasmid unnamed2, complete sequence	71843-71869	7	0.741
NC_021658_2	2.7|610878|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	610878-610913	36	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	13873-13908	8	0.778
NC_021658_8	8.1|3493336|35|NC_021658|CRISPRCasFinder	3493336-3493370	35	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	57464-57498	8	0.771
NC_021658_26	26.1|7538323|34|NC_021658|CRISPRCasFinder	7538323-7538356	34	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2981388-2981421	8	0.765
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NZ_CP015737	Shinella sp. HZN7 plasmid pShin-01, complete sequence	69920-69950	8	0.742
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NC_022050	Paracoccus aminophilus JCM 7686 plasmid pAMI8, complete sequence	111526-111556	8	0.742
NC_021658_27	27.1|7992042|31|NC_021658|CRISPRCasFinder	7992042-7992072	31	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1974294-1974324	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	815527-815557	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP016463	Bosea sp. RAC05 plasmid pBSY19_1, complete sequence	320916-320946	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_015314	Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence	26160-26190	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	LT599585	Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid	9847-9877	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_LR134450	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 8, complete sequence	204064-204094	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP027299	Streptomyces sp. SGAir0924 plasmid unnamed_5	328221-328251	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	207811-207841	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	175111-175141	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP021084	Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence	28927-28957	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	131164-131194	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP042333	Bosea sp. F3-2 plasmid pB32-2, complete sequence	25237-25267	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	358895-358925	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_LR026982	Rhodoplanes piscinae isolate Rhod_plasmid plasmid 1, complete sequence	51805-51835	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	KX853513	Uncultured virus isolate Rctr41k, partial genome	31001-31031	8	0.742
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_016767	Erwinia phage PEp14, complete genome	38345-38375	8	0.742
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP017574	Bacillus thuringiensis strain SCG04-02 plasmid PSCG364, complete sequence	265668-265698	8	0.742
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	514098-514128	8	0.742
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	533295-533325	8	0.742
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	503470-503500	8	0.742
NC_021658_37	37.28|9169355|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9169355-9169390	36	NZ_CP034911	Ensifer alkalisoli strain YIC4027 plasmid unnamed, complete sequence	102289-102324	8	0.778
NC_021658_37	37.42|9170372|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9170372-9170406	35	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	493996-494030	8	0.771
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	NZ_CP013744	Streptomyces sp. CdTB01 plasmid unnamed, complete sequence	72278-72307	8	0.733
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	NZ_LR134456	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence	112555-112584	8	0.733
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	NC_022049	Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence	202324-202353	8	0.733
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	MN585986	Microbacterium phage Ariadne, complete genome	29970-29999	8	0.733
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	MN586007	Microbacterium phage Smarties, complete genome	29970-29999	8	0.733
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	MN585980	Microbacterium phage Gina, complete genome	27851-27880	8	0.733
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	MN586059	Microbacterium phage Teamocil, complete genome	27950-27979	8	0.733
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	NC_011961	Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence	210109-210138	8	0.733
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	MF344569	Pseudomonas aeruginosa plasmid p12939-PER, complete sequence	178028-178057	8	0.733
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	95098-95127	8	0.733
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	95098-95127	8	0.733
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	145950-145979	8	0.733
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	NZ_CP021170	Paenibacillus bovis strain BD3526 plasmid unnamed1, complete sequence	85556-85585	8	0.733
NC_021658_44	44.1|9972900|30|NC_021658|CRISPRCasFinder	9972900-9972929	30	NC_022968	Enterobacteria phage 4MG, complete genome	30342-30371	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	1419872-1419901	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	449078-449107	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NC_016654	Rhodococcus phage REQ3, complete genome	28108-28137	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	1636513-1636542	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	115632-115661	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	118355-118384	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP015739	Shinella sp. HZN7 plasmid pShin-03, complete sequence	131920-131949	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	1576703-1576732	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	183169-183198	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	1181722-1181751	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	1561465-1561494	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	1609221-1609250	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	538534-538563	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	208120-208149	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	273046-273075	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	192712-192741	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	1482154-1482183	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	1031772-1031801	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	733118-733147	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	1070457-1070486	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	97832-97861	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	1619598-1619627	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP026653	Streptomyces dengpaensis strain XZHG99 plasmid unnamed1, complete sequence	25876-25905	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	437433-437462	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	325398-325427	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	112994-113023	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	115632-115661	8	0.733
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	GU936714	Synechococcus phage S-CBS2, complete genome	38948-38977	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MT639645	Mycobacterium phage PainterBoy, complete genome	28795-28824	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	MN096376	Mycobacterium phage Lucyedi, complete genome	28859-28888	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1726840-1726869	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1814012-1814041	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1648874-1648903	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1719092-1719121	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1647896-1647925	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1727392-1727421	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1727393-1727422	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1648867-1648896	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1648188-1648217	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1648856-1648885	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1727008-1727037	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1727006-1727035	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1726985-1727014	8	0.733
NC_021658_50	50.5|10766164|30|NC_021658|CRT	10766164-10766193	30	GU321093	Haloarcula hispanica pleomorphic virus 1, complete genome	6525-6554	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1569097-1569126	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	563291-563320	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	283762-283791	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LR134455	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 13, complete sequence	156436-156465	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	619829-619858	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	165479-165508	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	448324-448353	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	165494-165523	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	165493-165522	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	165491-165520	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	171590-171619	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	185948-185977	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LR134452	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence	62081-62110	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_LR134456	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence	310841-310870	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1859131-1859160	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	4310-4339	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	185948-185977	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	175454-175483	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	175455-175484	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	149940-149969	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	185957-185986	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	185975-186004	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	185947-185976	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	149938-149967	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_AP018520	Sphingobium sp. YG1 plasmid pYGP1, complete sequence	56094-56123	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP013554	Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence	312126-312155	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP013560	Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence	294677-294706	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	AP021850	Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome	124057-124086	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1852400-1852429	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP013565	Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence	312126-312155	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	230261-230290	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1831047-1831076	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_022061	Mycobacterium phage KayaCho, complete genome	67029-67058	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1781772-1781801	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	150022-150051	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	933312-933341	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	150026-150055	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	945849-945878	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	849143-849172	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_AP022566	Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence	95537-95566	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	174933-174962	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	937660-937689	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	1259842-1259871	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP048284	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248b, complete sequence	246345-246374	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	201690-201719	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	245217-245246	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP054026	Rhizobium sp. JKLM12A2 plasmid pPR12A205, complete sequence	289493-289522	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	657104-657133	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	763602-763631	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1308945-1308974	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	341372-341401	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_019957	Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence	65180-65209	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	484356-484385	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	901727-901756	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	937649-937678	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1308912-1308941	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1307717-1307746	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	828021-828050	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1307754-1307783	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	310495-310524	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	286573-286602	8	0.733
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP030829	Neorhizobium sp. NCHU2750 plasmid pNCHU2750b, complete sequence	133602-133631	8	0.733
NC_021658_58	58.1|12836862|31|NC_021658|CRISPRCasFinder	12836862-12836892	31	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	212365-212395	8	0.742
NC_021658_7	7.1|3465111|32|NC_021658|CRISPRCasFinder	3465111-3465142	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	902997-903028	9	0.719
NC_021658_8	8.1|3493336|35|NC_021658|CRISPRCasFinder	3493336-3493370	35	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	486482-486516	9	0.743
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	920230-920260	9	0.71
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3260106-3260136	9	0.71
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP024924	Sphingomonas sp. Cra20 plasmid unnamed, complete sequence	145317-145347	9	0.71
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP023152	Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence	122998-123028	9	0.71
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	452858-452888	9	0.71
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP006993	Methylobacterium sp. AMS5 plasmid pAMS5a, complete sequence	100046-100076	9	0.71
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	421684-421714	9	0.71
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	NC_012848	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132501, complete sequence	270617-270647	9	0.71
NC_021658_33	33.2|8825343|31|NC_021658|CRISPRCasFinder	8825343-8825373	31	MF668280	Mycobacterium phage Phabba, complete genome	39115-39145	9	0.71
NC_021658_37	37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9168915-9168950	36	KT919973	Vibrio phage phi-ST2, complete genome	155664-155699	9	0.75
NC_021658_37	37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9168915-9168950	36	NC_023568	Vibrio phage VH7D, complete genome	167981-168016	9	0.75
NC_021658_37	37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9168915-9168950	36	KT919972	Vibrio phage phi-Grn1, complete genome	96684-96719	9	0.75
NC_021658_37	37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9168915-9168950	36	MK568540	Vibrio phage ValB1 HC, complete genome	92494-92529	9	0.75
NC_021658_37	37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9168915-9168950	36	KP671755	Vibrio phage ValKK3, complete genome	145655-145690	9	0.75
NC_021658_37	37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9168915-9168950	36	MT612989	Vibrio phage vB_ValM_R11Z, complete genome	111909-111944	9	0.75
NC_021658_37	37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9168915-9168950	36	MT612988	Vibrio phage vB_ValM_R10Z, complete genome	112453-112488	9	0.75
NC_021658_37	37.29|9169427|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9169427-9169462	36	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	1520262-1520297	9	0.75
NC_021658_37	37.29|9169427|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9169427-9169462	36	MK686071	Streptomyces phage Mischief19, complete genome	36756-36791	9	0.75
NC_021658_37	37.42|9170372|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9170372-9170406	35	NZ_CP031163	Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdI, complete sequence	410431-410465	9	0.743
NC_021658_37	37.42|9170372|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9170372-9170406	35	NZ_CP049837	Gordonia terrae strain RL-JC02 plasmid pPAE01, complete sequence	32656-32690	9	0.743
NC_021658_37	37.42|9170372|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9170372-9170406	35	NZ_CP020372	Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs485, complete sequence	68701-68735	9	0.743
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	787207-787236	9	0.7
NC_021658_41	41.2|9547731|30|NC_021658|CRISPRCasFinder	9547731-9547760	30	NZ_CP009113	Rhodococcus opacus strain 1CP plasmid pR1CP2, complete sequence	27519-27548	9	0.7
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	CP054922	Streptomyces sp. NA03103 plasmid unnamed2, complete sequence	26854-26883	9	0.7
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	CP054922	Streptomyces sp. NA03103 plasmid unnamed2, complete sequence	56976-57005	9	0.7
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP020556	Streptomyces sp. Sge12 plasmid pSGE, complete sequence	74345-74374	9	0.7
NC_021658_50	50.4|10766116|30|NC_021658|CRT	10766116-10766145	30	NZ_CP009572	Sphingomonas taxi strain ATCC 55669 plasmid STP1, complete sequence	117074-117103	9	0.7
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP022549	Sphingorhabdus sp. YGSMI21 plasmid unnamed, complete sequence	55832-55861	9	0.7
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	442364-442393	9	0.7
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	156483-156512	9	0.7
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	259771-259800	9	0.7
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	242371-242400	9	0.7
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP021355	Rhodococcus sp. S2-17 plasmid pRB98, complete sequence	47624-47653	9	0.7
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	359796-359825	9	0.7
NC_021658_58	58.1|12836862|31|NC_021658|CRISPRCasFinder	12836862-12836892	31	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	458619-458649	9	0.71
NC_021658_58	58.1|12836862|31|NC_021658|CRISPRCasFinder	12836862-12836892	31	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	361326-361356	9	0.71
NC_021658_58	58.1|12836862|31|NC_021658|CRISPRCasFinder	12836862-12836892	31	NZ_CP018077	Sulfitobacter sp. AM1-D1 plasmid unnamed1, complete sequence	174262-174292	9	0.71
NC_021658_2	2.52|614173|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	614173-614208	36	NZ_CP023158	Xanthomonas citri pv. malvacearum strain AR81009 plasmid unnamed3, complete sequence	19062-19097	10	0.722
NC_021658_2	2.57|614541|38|NC_021658|CRT	614541-614578	38	NZ_AP014810	Methylorubrum populi strain P-1M plasmid pMPPM01, complete sequence	46897-46934	10	0.737
NC_021658_31	31.8|8416211|35|NC_021658|PILER-CR,CRISPRCasFinder,CRT	8416211-8416245	35	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	680524-680558	10	0.714
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NZ_CP013419	Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence	93613-93643	10	0.677
NC_021658_37	37.29|9169427|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	9169427-9169462	36	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	828941-828976	10	0.722
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	665837-665866	10	0.667
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	200508-200537	10	0.667
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_CP048424	Rhizobium daejeonense strain KACC 13094 plasmid unnamed1, complete sequence	118514-118540	10	0.63
NC_021658_59	59.1|12863912|27|NC_021658|CRISPRCasFinder	12863912-12863938	27	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	1131120-1131146	10	0.63
NC_021658_2	2.52|614173|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	614173-614208	36	NZ_CP018048	Pseudomonas aeruginosa strain DN1 plasmid unnamed1, complete sequence	177325-177360	11	0.694
NC_021658_2	2.52|614173|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR	614173-614208	36	NZ_AP015030	Pseudomonas putida strain KF715 plasmid pKF715A, complete sequence	351509-351544	11	0.694
NC_021658_33	33.1|8825289|31|NC_021658|CRISPRCasFinder	8825289-8825319	31	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	164706-164736	11	0.645
NC_021658_50	50.6|10766212|30|NC_021658|CRT	10766212-10766241	30	NC_020275	Mycobacterium intracellulare subsp. yongonense 05-1390 plasmid pMyong1, complete sequence	118769-118798	11	0.633

1. spacer 17.2|5329206|19|NC_021658|CRT matches to NZ_CP010826 (Thermus aquaticus Y51MC23 plasmid pTA78, complete sequence) position: , mismatch: 0, identity: 1.0

cgggggcggaggggcaggg	CRISPR spacer
cgggggcggaggggcaggg	Protospacer
*******************

2. spacer 23.2|6544768|22|NC_021658|CRISPRCasFinder matches to NZ_CP054608 (Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed9, complete sequence) position: , mismatch: 1, identity: 0.955

aggaagcgcgggcgcaggcggc	CRISPR spacer
aggacgcgcgggcgcaggcggc	Protospacer
**** *****************

3. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 1, identity: 0.968

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcggtccggtcggtccggtcggtccggtccg	Protospacer
***************************** *

4. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 1, identity: 0.968

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcggtccggtcggtccggtcggtccggtccg	Protospacer
***************************** *

5. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 1, identity: 0.968

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcggtccggtcggtccggtcggtccggtccg	Protospacer
***************************** *

6. spacer 1.2|609491|23|NC_021658|CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 2, identity: 0.913

atcgggacgcgctggcgatcgcg	CRISPR spacer
attgggacgcgctggcgatctcg	Protospacer
**.***************** **

7. spacer 1.2|609491|23|NC_021658|CRT matches to AP021850 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome) position: , mismatch: 2, identity: 0.913

atcgggacgcgctggcgatcgcg	CRISPR spacer
agcgggacgcgcgggcgatcgcg	Protospacer
* ********** **********

8. spacer 1.2|609491|23|NC_021658|CRT matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 2, identity: 0.913

atcgggacgcgctggcgatcgcg	CRISPR spacer
atcgcgacgtgctggcgatcgcg	Protospacer
**** ****.*************

9. spacer 1.4|609577|23|NC_021658|CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 2, identity: 0.913

atcgggacgcgctggcgatcgcg	CRISPR spacer
attgggacgcgctggcgatctcg	Protospacer
**.***************** **

10. spacer 1.4|609577|23|NC_021658|CRT matches to AP021850 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome) position: , mismatch: 2, identity: 0.913

atcgggacgcgctggcgatcgcg	CRISPR spacer
agcgggacgcgcgggcgatcgcg	Protospacer
* ********** **********

11. spacer 1.4|609577|23|NC_021658|CRT matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 2, identity: 0.913

atcgggacgcgctggcgatcgcg	CRISPR spacer
atcgcgacgtgctggcgatcgcg	Protospacer
**** ****.*************

12. spacer 1.6|609663|23|NC_021658|CRT matches to NC_023498 (Mycobacterium phage Validus, complete genome) position: , mismatch: 2, identity: 0.913

accgggacgcgctggcgatcacg	CRISPR spacer
accgcgccgcgctggcgatcacg	Protospacer
**** * ****************

13. spacer 10.6|3762890|22|NC_021658|CRT matches to MN234185 (Mycobacterium phage Lemuria, complete genome) position: , mismatch: 2, identity: 0.909

tcccggaaccggagccggcgcc	CRISPR spacer
ccccggaaccggagccgtcgcc	Protospacer
.**************** ****

14. spacer 23.2|6544768|22|NC_021658|CRISPRCasFinder matches to NZ_CP044991 (Deinococcus sp. AJ005 plasmid p115k, complete sequence) position: , mismatch: 2, identity: 0.909

aggaagcgcgggcgcaggcggc	CRISPR spacer
aggaagcgcgggcgcgggcggg	Protospacer
***************.***** 

15. spacer 23.2|6544768|22|NC_021658|CRISPRCasFinder matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 2, identity: 0.909

aggaagcgcgggcgcaggcggc	CRISPR spacer
aggaagcgcgggcgaaggcggt	Protospacer
************** ******.

16. spacer 23.2|6544768|22|NC_021658|CRISPRCasFinder matches to NZ_CP015530 (Rhodococcus sp. WB1 plasmid pWB1, complete sequence) position: , mismatch: 2, identity: 0.909

aggaagcgcgggcgcaggcggc	CRISPR spacer
aggaagcgcgggcgaaggcggt	Protospacer
************** ******.

17. spacer 23.2|6544768|22|NC_021658|CRISPRCasFinder matches to NZ_CP025552 (Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.909

aggaagcgcgggcgcaggcggc	CRISPR spacer
cggaagcgcgggcgctggcggc	Protospacer
 ************** ******

18. spacer 23.2|6544768|22|NC_021658|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 2, identity: 0.909

aggaagcgcgggcgcaggcggc	CRISPR spacer
cggaagcgcgggcgcgggcggc	Protospacer
 **************.******

19. spacer 23.2|6544768|22|NC_021658|CRISPRCasFinder matches to JN698994 (Mycobacterium phage DS6A, complete genome) position: , mismatch: 2, identity: 0.909

aggaagcgcgggcgcaggcggc	CRISPR spacer
tggaagcgcgggcgcaggccgc	Protospacer
 ****************** **

20. spacer 1.1|609448|23|NC_021658|CRT matches to NZ_CP049159 (Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
ctccaggtcgcgccgtggtcgtt	Protospacer
  **********.**********

21. spacer 1.1|609448|23|NC_021658|CRT matches to NZ_CP049320 (Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
ctccaggtcgcgccgtggtcgtt	Protospacer
  **********.**********

22. spacer 1.1|609448|23|NC_021658|CRT matches to MT521993 (Gordonia phage RedWattleHog, complete genome) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
gaccagggcgcgtcgtggtcgca	Protospacer
******* *************. 

23. spacer 1.1|609448|23|NC_021658|CRT matches to MN586040 (Gordonia phage Stormageddon, complete genome) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
gaccagggcgcgtcgtggtcgca	Protospacer
******* *************. 

24. spacer 1.2|609491|23|NC_021658|CRT matches to NZ_LR594669 (Variovorax sp. SRS16 plasmid 4) position: , mismatch: 3, identity: 0.87

atcgggacgcgctggcgatcgcg	CRISPR spacer
acaaggacgcgctggcgatcgcg	Protospacer
*. .*******************

25. spacer 1.3|609534|23|NC_021658|CRT matches to NZ_CP049159 (Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
ctccaggtcgcgccgtggtcgtt	Protospacer
  **********.**********

26. spacer 1.3|609534|23|NC_021658|CRT matches to NZ_CP049320 (Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
ctccaggtcgcgccgtggtcgtt	Protospacer
  **********.**********

27. spacer 1.3|609534|23|NC_021658|CRT matches to MT521993 (Gordonia phage RedWattleHog, complete genome) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
gaccagggcgcgtcgtggtcgca	Protospacer
******* *************. 

28. spacer 1.3|609534|23|NC_021658|CRT matches to MN586040 (Gordonia phage Stormageddon, complete genome) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
gaccagggcgcgtcgtggtcgca	Protospacer
******* *************. 

29. spacer 1.4|609577|23|NC_021658|CRT matches to NZ_LR594669 (Variovorax sp. SRS16 plasmid 4) position: , mismatch: 3, identity: 0.87

atcgggacgcgctggcgatcgcg	CRISPR spacer
acaaggacgcgctggcgatcgcg	Protospacer
*. .*******************

30. spacer 1.5|609620|23|NC_021658|CRT matches to NZ_CP049159 (Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
ctccaggtcgcgccgtggtcgtt	Protospacer
  **********.**********

31. spacer 1.5|609620|23|NC_021658|CRT matches to NZ_CP049320 (Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
ctccaggtcgcgccgtggtcgtt	Protospacer
  **********.**********

32. spacer 1.5|609620|23|NC_021658|CRT matches to MT521993 (Gordonia phage RedWattleHog, complete genome) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
gaccagggcgcgtcgtggtcgca	Protospacer
******* *************. 

33. spacer 1.5|609620|23|NC_021658|CRT matches to MN586040 (Gordonia phage Stormageddon, complete genome) position: , mismatch: 3, identity: 0.87

gaccaggtcgcgtcgtggtcgtt	CRISPR spacer
gaccagggcgcgtcgtggtcgca	Protospacer
******* *************. 

34. spacer 10.3|3762764|22|NC_021658|CRT matches to NZ_CP016621 (Microvirga ossetica strain V5/3m plasmid unnamed5, complete sequence) position: , mismatch: 3, identity: 0.864

gcccgggatcgggatcgatgtc	CRISPR spacer
aggcgggatcgggatcgatgtc	Protospacer
.  *******************

35. spacer 10.6|3762890|22|NC_021658|CRT matches to NZ_CP047184 (Rathayibacter sp. VKM Ac-2801 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.864

tcccggaaccggagccggcgcc	CRISPR spacer
ggacggaaccggagccggcgcc	Protospacer
   *******************

36. spacer 10.6|3762890|22|NC_021658|CRT matches to NZ_CP047181 (Rathayibacter festucae strain VKM Ac-2802 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.864

tcccggaaccggagccggcgcc	CRISPR spacer
ggacggaaccggagccggcgcc	Protospacer
   *******************

37. spacer 20.1|5884214|25|NC_021658|CRISPRCasFinder matches to NZ_CP017947 (Bosea sp. Tri-49 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.88

ggcccgcgcacccgtgggtgtcgct	CRISPR spacer
cgcccgcgcacccgtgggtgccgcc	Protospacer
 *******************.***.

38. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 3, identity: 0.889

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggcggcggcggccagggtggc	Protospacer
*********..*************** 

39. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP029358 (Azospirillum sp. CFH 70021 plasmid unnamed3) position: , mismatch: 3, identity: 0.889

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggcggcggcggccagggtggc	Protospacer
*********..*************** 

40. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 3, identity: 0.889

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccaggctgcg	Protospacer
* ******************** ** *

41. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 4, identity: 0.846

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccgccgcgtcctggagctcgccga	Protospacer
. ******** ************.**

42. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to CP006880 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence) position: , mismatch: 4, identity: 0.846

ggccgccgcggcctggagctcgctga	CRISPR spacer
ggccgccgccgcctcgagctcgctcg	Protospacer
********* **** ********* .

43. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 4, identity: 0.846

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccgccgcgtcctggagctcgccga	Protospacer
. ******** ************.**

44. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP022370 (Bosea sp. AS-1 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

ggccgccgcggcctggagctcgctga	CRISPR spacer
ggccgccgcggcctcgagctcgaagg	Protospacer
************** *******  *.

45. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NC_008712 (Paenarthrobacter aurescens TC1 plasmid pTC1, complete sequence) position: , mismatch: 4, identity: 0.846

ggccgccgcggcctggagctcgctga	CRISPR spacer
ggcggccgcggcctggagctcccggg	Protospacer
*** ***************** * *.

46. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NC_004808 (Streptomyces rochei plasmid pSLA2-L DNA, complete sequence) position: , mismatch: 4, identity: 0.846

ggccgccgcggcctggagctcgctga	CRISPR spacer
ggccgccgcggcctcgcgctcgcgca	Protospacer
************** * ******  *

47. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_005342 (Burkholderia phage Bcep43, complete genome) position: , mismatch: 4, identity: 0.871

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tcgacgcgctcgacgcgttcaac-cagtcgat	Protospacer
*****************.** ** *.***** 

48. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to EF602154 (Burkholderia phage BcepNY3, complete genome) position: , mismatch: 4, identity: 0.871

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tcgacgcgctcgacgcgttcaac-cagtcgat	Protospacer
*****************.** ** *.***** 

49. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to AY369265 (Burkholderia cenocepacia phage Bcep1, complete genome) position: , mismatch: 4, identity: 0.871

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tcgacgcgctcgacgcgttcaac-cagtcgat	Protospacer
*****************.** ** *.***** 

50. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_004333 (Burkholderia phage Bcep781, complete genome) position: , mismatch: 4, identity: 0.871

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tcgacgcgctcgacgcgttcaac-cagtcgat	Protospacer
*****************.** ** *.***** 

51. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to AY368235 (Burkholderia cepacia phage Bcep43, complete genome) position: , mismatch: 4, identity: 0.871

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tcgacgcgctcgacgcgttcaac-cagtcgat	Protospacer
*****************.** ** *.***** 

52. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to AF543311 (Burkholderia cepacia phage Bcep781, complete genome) position: , mismatch: 4, identity: 0.871

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tcgacgcgctcgacgcgttcaac-cagtcgat	Protospacer
*****************.** ** *.***** 

53. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_005263 (Burkholderia phage Bcep1, complete genome) position: , mismatch: 4, identity: 0.871

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tcgacgcgctcgacgcgttcaac-cagtcgat	Protospacer
*****************.** ** *.***** 

54. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP013855 (Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence) position: , mismatch: 4, identity: 0.871

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
ccggtccgggcggtccgggcggtccggtccg	Protospacer
.******** ******** ********** *

55. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gcaggcggcaacggcggccagggcggg	Protospacer
   ********************.***

56. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
atcggcggcaacggcggccagggcggc	Protospacer
  *********************.** 

57. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to MH884648 (Caulobacter phage Kronos, complete genome) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaacggcggccgggttggt	Protospacer
 ******************.** *** 

58. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to MH744418 (Streptomyces phage JustBecause, complete genome) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgtgacggcaacggcggccagggtgcc	Protospacer
**.*.********************  

59. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to MT310898 (Streptomyces phage Kela, complete genome) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgtgacggcaacggcggccagggtgcc	Protospacer
**.*.********************  

60. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaacggcggccggggtaag	Protospacer
 ******************.****..*

61. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

62. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

63. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

64. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

65. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

66. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

67. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

68. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

69. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

70. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

71. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

72. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

73. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

74. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaaaggcggccacggtgcg	Protospacer
 ********** ******** **** *

75. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to MN234199 (Mycobacterium phage Ekdilam, complete genome) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
agcggcggcaacggcgggcagggctgg	Protospacer
 **************** *****. **

76. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

77. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

78. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

79. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

80. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

81. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

82. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

83. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

84. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

85. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

86. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

87. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

88. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP044082 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggccatggcggccagggcgcg	Protospacer
********* *.***********.* *

89. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP031080 (Paracoccus yeei strain CCUG 32053 plasmid pYEE2, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggccatggcggccagggcgcg	Protospacer
********* *.***********.* *

90. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

91. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

92. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

93. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

94. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

95. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

96. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

97. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

98. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

99. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

100. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

101. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

102. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

103. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

104. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

105. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

106. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

107. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

108. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

109. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

110. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

111. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

112. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

113. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

114. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

115. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

116. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

117. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

118. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

119. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

120. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

121. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

122. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

123. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

124. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

125. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

126. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

127. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

128. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

129. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

130. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

131. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

132. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

133. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

134. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

135. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

136. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

137. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

138. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

139. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.852

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cccggcggcaacggcggccagactgcg	Protospacer
* *******************. ** *

140. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to AP021851 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-2 DNA, complete genome) position: , mismatch: 4, identity: 0.867

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
gcctgcgcgacgtcctcggtggccgcgccg	Protospacer
 **.********************* **.*

141. spacer 43.1|9915053|27|NC_021658|CRISPRCasFinder matches to NC_009956 (Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI02, complete sequence) position: , mismatch: 4, identity: 0.852

gccagtgtgacggcgcggcgagctcga	CRISPR spacer
gccagtgtggcggcgcggcgtgctcct	Protospacer
*********.********** ****  

142. spacer 47.2|10090957|29|NC_021658|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 4, identity: 0.862

gaggcgct-ccacgcgcgcctcgctgcgcg	CRISPR spacer
-cggcgccaccacgcgcgcctcggtgcgcg	Protospacer
  *****. ************** ******

143. spacer 48.1|10333345|29|NC_021658|CRISPRCasFinder matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 4, identity: 0.862

-ggatgtcggcctgggtcctggggcgcagg	CRISPR spacer
cggacg-cggcccgggtcctggggcgcggg	Protospacer
 ***.* *****.**************.**

144. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 4, identity: 0.867

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgctcggcaccgccgccggcgcgccgcgc	Protospacer
 ****** **************** *** *

145. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 4, identity: 0.867

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgctcggcaccgccgccggcgcgccgcgc	Protospacer
 ****** **************** *** *

146. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.867

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgctcggcaccgccgccggcgcgccgcgc	Protospacer
 ****** **************** *** *

147. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 4, identity: 0.867

gcgctcg-ccaccgccgccggcgcggcgctc	CRISPR spacer
-cgctcgtccaccgccgccgccgcggcgcca	Protospacer
 ****** ************ ********. 

148. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 4, identity: 0.867

-gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
aacgc-cggcaccgccgccggcgccgcgctc	Protospacer
 .*** ** *************** ******

149. spacer 50.6|10766212|30|NC_021658|CRT matches to MN062720 (Microbacterium phage FuzzBuster, complete genome) position: , mismatch: 4, identity: 0.867

-gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cgcggt-gccaccgccgacggggcggcgctc	Protospacer
 *** * ********** *** *********

150. spacer 52.2|11367097|25|NC_021658|CRISPRCasFinder matches to NZ_CP020539 (Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence) position: , mismatch: 4, identity: 0.84

gttgctgacctggccgccccagagg	CRISPR spacer
cttgctgacctgcccgccccacagc	Protospacer
 *********** ******** ** 

151. spacer 52.2|11367097|25|NC_021658|CRISPRCasFinder matches to LN610585 (Pseudomonas phage vB_PaeS_PAO1_Ab20, complete genome) position: , mismatch: 4, identity: 0.84

gttgctgacctggccgccccagagg	CRISPR spacer
catggtgacctggccgccgcagagg	Protospacer
  ** ************* ******

152. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 4, identity: 0.852

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
gcccggcgcgatcgaagcgatcgcccg	Protospacer
 ************* **********  

153. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_CP009123 (Sphingopyxis fribergensis strain Kp5.2 plasmid pSfKp5.2, complete sequence) position: , mismatch: 4, identity: 0.852

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
tcccggcgcggtcgcagcgatcgtcaa	Protospacer
.*********.************.** 

154. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 4, identity: 0.852

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
cgccgacgcgatcgccgcgatcgccag	Protospacer
* ***.********* ********** 

155. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 4, identity: 0.852

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
catcggcgcgatcgcagcgaccgccgc	Protospacer
* .*****************.****.*

156. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 4, identity: 0.852

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
catcggcgcgatcgcagcgaccgccgc	Protospacer
* .*****************.****.*

157. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_CP035000 (Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence) position: , mismatch: 4, identity: 0.852

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
cgccggcgagatcgaagcgatcgccgc	Protospacer
* ****** ***** **********.*

158. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP021813 (Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence) position: , mismatch: 5, identity: 0.808

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccgccgcggcctggagctcgcgcg	Protospacer
. *********************  .

159. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_LN831789 (Streptomyces leeuwenhoekii strain type strain (C34 = DSM 42122 = NRRL B-24963) plasmid pSLE2) position: , mismatch: 5, identity: 0.808

ggccgccgcggcctggagctcgctga	CRISPR spacer
ggcggccgcggcctggcgctcgcgct	Protospacer
*** ************ ******   

160. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP016084 (Streptomyces sp. SAT1 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.808

ggccgccgcggcctggagctcgctga	CRISPR spacer
ggcggccgcggcctggcgctcgcgtt	Protospacer
*** ************ ******   

161. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 5, identity: 0.808

ggccgccgcggcctggagctcgctga	CRISPR spacer
tctcgccgcgtcctggagctggctga	Protospacer
  .******* ********* *****

162. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP025552 (Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

ggccgccgcggcctggagctcgctga	CRISPR spacer
ggcggccgcggcctggcgctcgcgtt	Protospacer
*** ************ ******   

163. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
gccgcgcgctcgacgcgctcgacgcggtcaa	Protospacer
 * .**************** ********.*

164. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

165. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

166. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

167. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

168. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

169. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

170. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

171. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

172. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

173. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

174. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

175. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

176. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

177. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

178. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

179. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

180. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

181. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

182. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

183. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

184. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

185. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

186. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

187. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

188. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

189. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

190. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

191. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

192. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

193. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

194. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

195. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

196. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

197. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

198. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

199. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

200. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

201. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

202. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

203. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

204. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

205. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

206. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

207. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

208. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

209. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

210. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

211. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

212. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

213. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

214. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

215. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

216. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

217. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

218. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

219. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

220. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

221. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

222. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

223. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

224. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

225. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tgcacgcgctcgacgcgctcaacgc-ctcgat	Protospacer
*  ***************** ****  **** 

226. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022999 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence) position: , mismatch: 5, identity: 0.839

tcgacgcgctcgacgcgctccacgcggtcga-	CRISPR spacer
tcgacgcgctcgccccgctccac-cgatcggg	Protospacer
************ * ******** **.***. 

227. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP022605 (Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
taggtccggtaggtccggtaggtccggaggg	Protospacer
* ******** ******** *******  **

228. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP024895 (Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
cccgtccggtccgtccggtccgtccggtccg	Protospacer
.* ******** ******** ******** *

229. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 5, identity: 0.839

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcgcggcggtccgtcaggtcggtccggtcgg	Protospacer
***   ***** *** ***************

230. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NC_014159 (Tsukamurella paurometabola DSM 20162 plasmid pTpau01, complete sequence) position: , mismatch: 5, identity: 0.839

tcggtccggtcggtccggtcggt-ccggtcgg	CRISPR spacer
acggtgcggtcggtgcggtcggtcccggtct-	Protospacer
 **** ******** ******** ******  

231. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ctcttcggcaacggcggcaagggtggt	Protospacer
* *  ************* ******* 

232. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggcaacggcggcacgggcacg	Protospacer
******************  ***.. *

233. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to JN698995 (Mycobacterium phage Dori, complete genome) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
actggcggcaagggcggccagggtggc	Protospacer
  .******** ************** 

234. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP049750 (Rhodococcus fascians A21d2 plasmid unnamed1) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
accggcggcaacgccggccagggcgga	Protospacer
  *********** *********.**.

235. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NC_017966 (Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
tacggcggcaagggcggcaagggtggc	Protospacer
..********* ****** ******* 

236. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ttcggcggcaacggcggcaaaggtggc	Protospacer
. **************** *.***** 

237. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to MN585973 (Mycobacterium phage StAnnes, complete genome) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
aacggcggcaacggcggcaagggcggc	Protospacer
 .**************** ****.** 

238. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to MG944221 (Mycobacterium phage Scowl, complete genome) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
aacggcggcaacggcggcaagggcggc	Protospacer
 .**************** ****.** 

239. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to MN813686 (Mycobacterium phage BirdsNest, complete genome) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gtcggcggcaagggcggcaagggtggc	Protospacer
  ********* ****** ******* 

240. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to KT309034 (Mycobacterium phage Dante, complete genome) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
aacggcggcaacggcggcaagggcggc	Protospacer
 .**************** ****.** 

241. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NC_021538 (Mycobacterium phage Job42, complete genome) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
aacggcggcaacggcggcaagggcggc	Protospacer
 .**************** ****.** 

242. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NC_026584 (Mycobacterium phage Minerva, complete genome) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
aacggcggcaacggcggcaagggcggc	Protospacer
 .**************** ****.** 

243. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

244. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggcaagggcggccatggagtc	Protospacer
*********** ******** ** *  

245. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

246. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

247. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

248. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

249. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to LR743530 (Xanthomonas phage Suba genome assembly, chromosome: 1) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cagggcggcaacggcggcaatggtggc	Protospacer
*. *************** * ***** 

250. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to AP018486 (Mycobacterium phage PP DNA, complete genome) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgtggcggcaacggcggccagcggcgc	Protospacer
**.****************** *  * 

251. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

252. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

253. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

254. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

255. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

256. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP046574 (Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggccacggcgaccagggagaa	Protospacer
********* ******.****** *..

257. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cagggcggcaacggcggccaggccggc	Protospacer
*. ******************* .** 

258. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

259. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

260. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

261. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gggggcggcaacggcggccaacgtgga	Protospacer
 * *****************. ****.

262. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to MG925349 (Mycobacterium phage Mendokysei, complete genome) position: , mismatch: 5, identity: 0.815

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ccgggcggcaagggcggcaagggtggc	Protospacer
*  ******** ****** ******* 

263. spacer 43.1|9915053|27|NC_021658|CRISPRCasFinder matches to NC_008010 (Deinococcus geothermalis DSM 11300 plasmid pDGEO01, complete sequence) position: , mismatch: 5, identity: 0.815

gccagtgtgacggcgcggcgagctcga	CRISPR spacer
gccagtgtgacggcgcggggagagagg	Protospacer
****************** ***   *.

264. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to NZ_CP010057 (Hymenobacter sp. DG25B plasmid, complete sequence) position: , mismatch: 5, identity: 0.833

gccccggagcaggtgctgcaggcgtacgcg	CRISPR spacer
gccccggagcaggtgcagcaggcggcggcc	Protospacer
**************** *******   ** 

265. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to MT121966 (Pseudomonas phage SC_8_H2H8_2017 translation initiation factor IF-3, replication protein P, integrase, terminase, terminase A, capsid family protein, tail protein, and minor tail protein L genes, complete cds) position: , mismatch: 5, identity: 0.833

gccccggagcaggtgctgcaggcgtacgcg---	CRISPR spacer
gctccggagcagatgctgcaggc---cgcgatt	Protospacer
**.*********.**********   ****   

266. spacer 47.2|10090957|29|NC_021658|CRISPRCasFinder matches to MN586020 (Microbacterium phage Megan, complete genome) position: , mismatch: 5, identity: 0.828

gaggcgctccacgcgcgcctcgctgcgcg	CRISPR spacer
cacgcgctccacgcgcgcctccatgcgag	Protospacer
 * ******************  **** *

267. spacer 50.5|10766164|30|NC_021658|CRT matches to MN234223 (Mycobacterium phage Philly, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

268. spacer 50.5|10766164|30|NC_021658|CRT matches to KP027207 (Mycobacterium phage Chandler, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

269. spacer 50.5|10766164|30|NC_021658|CRT matches to MN096360 (Mycobacterium phage Rita1961, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

270. spacer 50.5|10766164|30|NC_021658|CRT matches to MG839014 (Mycobacterium phage RagingRooster, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

271. spacer 50.5|10766164|30|NC_021658|CRT matches to KJ194581 (Mycobacterium phage Audrey, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

272. spacer 50.5|10766164|30|NC_021658|CRT matches to KR080203 (Mycobacterium phage OrangeOswald, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

273. spacer 50.5|10766164|30|NC_021658|CRT matches to MH513976 (Mycobacterium phage Morty007, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

274. spacer 50.5|10766164|30|NC_021658|CRT matches to MH051265 (Mycobacterium phage Yahalom, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

275. spacer 50.5|10766164|30|NC_021658|CRT matches to MH316565 (Mycobacterium phage Mortcellus, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

276. spacer 50.5|10766164|30|NC_021658|CRT matches to MT310871 (Mycobacterium phage Jackstina, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

277. spacer 50.5|10766164|30|NC_021658|CRT matches to MK359357 (Mycobacterium phage RomaT, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

278. spacer 50.5|10766164|30|NC_021658|CRT matches to JF704095 (Mycobacterium phage Daisy, complete sequence) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

279. spacer 50.5|10766164|30|NC_021658|CRT matches to EU816589 (Mycobacterium phage Phaedrus, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

280. spacer 50.5|10766164|30|NC_021658|CRT matches to MN096359 (Mycobacterium phage Obutu, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

281. spacer 50.5|10766164|30|NC_021658|CRT matches to MK061414 (Mycobacterium phage Marley1013, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

282. spacer 50.5|10766164|30|NC_021658|CRT matches to MT952851 (Mycobacterium phage Gervas, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

283. spacer 50.5|10766164|30|NC_021658|CRT matches to MG925353 (Mycobacterium phage Nozo, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

284. spacer 50.5|10766164|30|NC_021658|CRT matches to KJ194584 (Mycobacterium phage Heathcliff, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

285. spacer 50.5|10766164|30|NC_021658|CRT matches to MN444872 (Mycobacterium phage SynergyX, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

286. spacer 50.5|10766164|30|NC_021658|CRT matches to MH576977 (Mycobacterium phage Tydolla, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

287. spacer 50.5|10766164|30|NC_021658|CRT matches to MG925338 (Mycobacterium phage ChaChing, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

288. spacer 50.5|10766164|30|NC_021658|CRT matches to NC_023742 (Mycobacterium phage Akoma, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

289. spacer 50.5|10766164|30|NC_021658|CRT matches to MG920059 (Mycobacterium phage Baloo, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

290. spacer 50.5|10766164|30|NC_021658|CRT matches to NC_023686 (Mycobacterium phage Gadjet, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

291. spacer 50.5|10766164|30|NC_021658|CRT matches to KR080205 (Mycobacterium phage Corofin, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

292. spacer 50.5|10766164|30|NC_021658|CRT matches to NC_041965 (Mycobacterium phage Athena, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

293. spacer 50.5|10766164|30|NC_021658|CRT matches to DQ398049 (Mycobacterium phage Pipefish, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

294. spacer 50.5|10766164|30|NC_021658|CRT matches to KF493879 (Mycobacterium phage Bernardo, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

295. spacer 50.5|10766164|30|NC_021658|CRT matches to MT310892 (Mycobacterium phage Compostia, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

296. spacer 50.5|10766164|30|NC_021658|CRT matches to JN699018 (Mycobacterium phage Kamiyu, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

297. spacer 50.5|10766164|30|NC_021658|CRT matches to NC_012027 (Mycobacterium phage Phlyer, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

298. spacer 50.5|10766164|30|NC_021658|CRT matches to MN444873 (Mycobacterium phage Abinghost, complete genome) position: , mismatch: 5, identity: 0.833

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gccatcgcggccttcggcgacaccgcgctc	Protospacer
**  .**********  *************

299. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP029835 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed5, complete sequence) position: , mismatch: 5, identity: 0.833

-gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
cacgacc-cggcattctccggcaccgcgctc	Protospacer
 .** ** **** *******.**********

300. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc---	CRISPR spacer
gcgctcgcgaccgccgccgtc---gcgctcgga	Protospacer
******** ********** *   ******   

301. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcgg-cgctc	CRISPR spacer
gtgctcgccaccgcggccggcgtggacgcg-	Protospacer
*.************ *******.** ***  

302. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015369 (Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p2, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cccttcgccaacgccgccggcgcgacgctc	Protospacer
 * .****** *************.*****

303. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP046100 (Rhodococcus sp. AQ5-07 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gacctcgccaccgccgccggcccggcgatg	Protospacer
*  ****************** ***** * 

304. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_013859 (Azospirillum sp. B510 plasmid pAB510e, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgatcgccaccgccgccgtcgcggccggc	Protospacer
*** *************** ******   *

305. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP054620 (Azospirillum oryzae strain KACC 14407 plasmid unnamed5, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgatcgccaccgccgccgtcgcggccggc	Protospacer
*** *************** ******   *

306. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP011771 (Croceicoccus naphthovorans strain PQ-2 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgctcgccacggccgcctgcgcggcggac	Protospacer
 ********** ****** ********  *

307. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP016453 (Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc-	CRISPR spacer
ccgctcgccatcgccaccggcgcgg-gcgcg	Protospacer
 *********.****.********* ** * 

308. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_028980 (Pseudomonas phage PAE1, complete genome) position: , mismatch: 5, identity: 0.833

-gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
aacgc-cgccaccgccgccgtcgcggagctg	Protospacer
 .*** ************** ***** *** 

309. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP009292 (Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctctccaccgccaccggcgcgacccgc	Protospacer
****** ********.********.* * *

310. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP047145 (Streptomyces sp. HF10 plasmid plas1, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcg-cggcgctc	CRISPR spacer
gcgctcgccaccgccgccgacgacctcgcc-	Protospacer
*******************.** *  ***. 

311. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP017244 (Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc---	CRISPR spacer
gcactcgccagcgccgccggc---gcgctcgcg	Protospacer
**.******* **********   ******   

312. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021027 (Rhizobium sp. TAL182 plasmid pRetTAL182c, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc-	CRISPR spacer
gcgatcgccgccgccgccggcgccg-gttcg	Protospacer
*** *****.************* * *.** 

313. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP014508 (Burkholderia sp. PAMC 28687 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgcc---accgccgccggcgcggcgctc	CRISPR spacer
---ctcggcctgaccgcggccggcgcggcgctc	Protospacer
   **** *   ***** ***************

314. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP013561 (Rhizobium phaseoli strain N841 plasmid pRphaN841d, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc-	CRISPR spacer
gcgatcgccgccgccgccggcgccg-gttcg	Protospacer
*** *****.************* * *.** 

315. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_008761 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP05, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgc-ggcgctc	CRISPR spacer
atgctcgccgccgcccccggcgcgggcgct-	Protospacer
..*******.***** ******* ****** 

316. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021125 (Rhizobium sp. Kim5 plasmid pRetKim5a, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc-	CRISPR spacer
gcgatcgccgccgccgccggcgccg-gttcg	Protospacer
*** *****.************* * *.** 

317. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP013514 (Rhizobium sp. N1314 plasmid pRspN1314c, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcgcggcgctc-	CRISPR spacer
gcgatcgccgccgccgccggcgccg-gttcg	Protospacer
*** *****.************* * *.** 

318. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 5, identity: 0.833

gcgctcgccaccgccgccggcg-cggcgctc	CRISPR spacer
gcgctcgcctacgccgccggcgccggcggc-	Protospacer
*********  *********** ***** . 

319. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP010860 (Marinovum algicola DG 898 plasmid pMaD5, complete sequence) position: , mismatch: 5, identity: 0.833

gcgct-cgccaccgccgccggcgcggcgctc	CRISPR spacer
-cgccgcgccgccgcccccggcgcggcgccc	Protospacer
 ***. ****.***** ************.*

320. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_LR134469 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence) position: , mismatch: 5, identity: 0.815

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
agcgagcgcgatcgcagcgatcggcac	Protospacer
  * .****************** ***

321. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NC_019957 (Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence) position: , mismatch: 5, identity: 0.815

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
gcagcgcgcgatcgccgcgatcgccac	Protospacer
 *   ********** ***********

322. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_LR134454 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence) position: , mismatch: 5, identity: 0.815

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
gtccgtcgcgatcgcggcgatcgccgc	Protospacer
 .*** *********.*********.*

323. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NC_017324 (Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccgtcgcggcctggagctcgcgcg	Protospacer
. ***.*****************  .

324. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP021819 (Sinorhizobium meliloti strain M162 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccgccgcggcctggagctagcgcg	Protospacer
. ****************** **  .

325. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccgtcgcggcctggagctcgcgcg	Protospacer
. ***.*****************  .

326. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP021805 (Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccggcgcggcctggagctcgcgcg	Protospacer
. *** *****************  .

327. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccgtcgcggcctggagctcgcgcg	Protospacer
. ***.*****************  .

328. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccggcgcggcctggagctcgcgcg	Protospacer
. *** *****************  .

329. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP045223 (Achromobacter xylosoxidans strain DN002 plasmid unnamed) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
cgccgccgctgcctggagctcgtccc	Protospacer
 ******** ************..  

330. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccggcgcggcctggagctcgcgcg	Protospacer
. *** *****************  .

331. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccgtcgcggcctggagctcgcgcg	Protospacer
. ***.*****************  .

332. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccggcgcggcctggagctcgcgcg	Protospacer
. *** *****************  .

333. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccgtcgcggcctggagctcgcgcg	Protospacer
. ***.*****************  .

334. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccgtcgcggcctggagctcgcgcg	Protospacer
. ***.*****************  .

335. spacer 4.1|2183523|26|NC_021658|CRISPRCasFinder matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 6, identity: 0.769

ggccgccgcggcctggagctcgctga	CRISPR spacer
acccggcgcggcctggagctcgcgcg	Protospacer
. *** *****************  .

336. spacer 8.1|3493336|35|NC_021658|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 6, identity: 0.829

gcggcgcctcggcggacggcgcggc--cggcagcgca	CRISPR spacer
gcggtgccttggcggacggcgcggcgtaggcggcg--	Protospacer
****.****.***************   ***.***  

337. spacer 8.1|3493336|35|NC_021658|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 6, identity: 0.829

gcggcgcctcggcggacggcgcggc--cggcagcgca	CRISPR spacer
gcggtgccttggcggacggcgcggcgtaggcggcg--	Protospacer
****.****.***************   ***.***  

338. spacer 8.1|3493336|35|NC_021658|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.829

gcggcgcctcggcggacggcgcggccg-gcagcgca	CRISPR spacer
gcggcggctcggcggacgccgcggcgacgctgcgc-	Protospacer
****** *********** ****** . ** **** 

339. spacer 26.1|7538323|34|NC_021658|CRISPRCasFinder matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 6, identity: 0.824

gcgccgcgcgccgtcccgcaggtcc---tgagcgcgg	CRISPR spacer
gcgcagcgcgccgtccagcaggtccaggcgagcg---	Protospacer
**** *********** ********   .*****   

340. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 6, identity: 0.806

cccggagctccaggccggcaagatc-acgccc	CRISPR spacer
cccggagcgccagcccggcaagacctacagc-	Protospacer
******** **** *********.* **. * 

341. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NZ_CP010957 (Sphingobium sp. YBL2 plasmid 3pYBL2-3, complete sequence) position: , mismatch: 6, identity: 0.806

cccggagctccaggccggcaagatcacgccc	CRISPR spacer
cgctgcgctccaggccggcaagagcgcgcgc	Protospacer
* * * ***************** *.*** *

342. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

cccggagctccaggccggcaagatc-acgccc	CRISPR spacer
cccggagcgccagcccggcaagacctacagc-	Protospacer
******** **** *********.* **. * 

343. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.806

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcggcgcgctcgccgcgctccacgcgcgctt	Protospacer
***.******** *************  *  

344. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP016082 (Streptomyces sp. SAT1 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.806

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
acgcagtgctcgacgcgctcgacgcgttcga	Protospacer
 **  *.************* ***** ****

345. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_LR134467 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence) position: , mismatch: 6, identity: 0.806

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcgacgcgctcgccgcgctcgacggtgccgg	Protospacer
************ ******* ***  *.**.

346. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_LR594691 (Variovorax sp. WDL1 plasmid 3) position: , mismatch: 6, identity: 0.806

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcgacgcgctcgacgagctcgacgtagtagt	Protospacer
*************** **** ***..** * 

347. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.806

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
ccgtcatgctcgacgcgctccacgacgtcga	Protospacer
.** *..*****************  *****

348. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP009572 (Sphingomonas taxi strain ATCC 55669 plasmid STP1, complete sequence) position: , mismatch: 6, identity: 0.806

tcgacgcgctcgacgcgctccacgcg-gtcga	CRISPR spacer
aggaggcgctcgacgcgttccacgcgcggcg-	Protospacer
  ** ************.******** * ** 

349. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP022371 (Bosea sp. AS-1 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.806

tcgacgcgctcgacgcgct---ccacgcggtcga	CRISPR spacer
tcgacacgctcgacgcgctacaccgcgcgtt---	Protospacer
*****.*************   **.**** *   

350. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP013855 (Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
gcggtccgggcggtccgggcggtccgggccc	Protospacer
 ******** ******** ******** *  

351. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
gttgcccggtcggtccggtcggtccgggcgt	Protospacer
 . *.********************** ** 

352. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to MK494124 (Mycobacterium phage Kristoff, complete genome) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
aaggcccggtcggtccggtcggaccggcagg	Protospacer
  **.***************** ****. **

353. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to MN586038 (Mycobacterium phage WalterMcMickey, complete genome) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
aaggcccggtcggtccggtcggaccggcagg	Protospacer
  **.***************** ****. **

354. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to JX411619 (Mycobacterium virus Rebeuca, complete genome) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
aaggcccggtcggtccggtcggaccggcagg	Protospacer
  **.***************** ****. **

355. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NC_041982 (Mycobacterium phage Twister, complete genome) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
aaggcccggtcggtccggtcggaccggcagg	Protospacer
  **.***************** ****. **

356. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
ccgcgcaggtcggtccggccggtccggtccg	Protospacer
.**  * ***********.********** *

357. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
ccgcgcaggtcggtccggccggtccggtccg	Protospacer
.**  * ***********.********** *

358. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
ccgcgcaggtcggtccggccggtccggtccg	Protospacer
.**  * ***********.********** *

359. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcgcggcggtccgtcaggtcggtccggtccg	Protospacer
***   ***** *** ************* *

360. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcgcggcggtccgtcaggtcggtccggtccg	Protospacer
***   ***** *** ************* *

361. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcgcggcggtccgtcaggtcggtccggtccg	Protospacer
***   ***** *** ************* *

362. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcgcggcggtccgtcaggtcggtccggtccg	Protospacer
***   ***** *** ************* *

363. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcgcggcggtccgtcaggtcggtccggtccg	Protospacer
***   ***** *** ************* *

364. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcgcggcggtccgtcaggtcggtccggtccg	Protospacer
***   ***** *** ************* *

365. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcgcggcggtccgtcaggtcggtccggtccg	Protospacer
***   ***** *** ************* *

366. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcgcggcggtccgtcaggtcggtccggtccg	Protospacer
***   ***** *** ************* *

367. spacer 35.1|9128365|27|NC_021658|CRISPRCasFinder matches to NZ_CP032928 (Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence) position: , mismatch: 6, identity: 0.778

aacggcggtcccgagggggagcacgcg	CRISPR spacer
gttggcggtcccgaggggaagaacgcc	Protospacer
. .***************.** **** 

368. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gcgggcggcaacggcggcaatggtggt	Protospacer
   *************** * ***** 

369. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP007144 (Hymenobacter swuensis DY53 plasmid pHsw1, complete sequence) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgtggcggcatcggcggccagggcctc	Protospacer
**.******* ************.   

370. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP036456 (Streptomonospora sp. M2 plasmid phiM2, complete sequence) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
ggcggcggcaacggcggacaggaagaa	Protospacer
 **************** ****. *..

371. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP020443 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gcgggcggccacggcgtccagggtggt	Protospacer
   ****** ****** ********* 

372. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgccgcggcaacggcggccagccgcgt	Protospacer
*** *****************    * 

373. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgccgcggcaacggcggccagccgcgt	Protospacer
*** *****************    * 

374. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP044079 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
gcgggcggccacggcgtccagggtggc	Protospacer
   ****** ****** ********* 

375. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_KJ599675 (Micrococcus sp. A7 plasmid pLMA7, complete sequence) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
acgggcggcaccggcggccagggcggc	Protospacer
   ******* ************.** 

376. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_KR152226 (Micrococcus sp. MG-2010-D12 plasmid pJD12, complete sequence) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
acgggcggcaccggcggccagggcggc	Protospacer
   ******* ************.** 

377. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NC_024972 (Micrococcus sp. A1 plasmid pLMA1, complete sequence) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
acgggcggcaccggcggccagggcggc	Protospacer
   ******* ************.** 

378. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to AF428260 (Propionibacterium phage phiB5, complete genome) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
aagggcggcgacggcggccagggcggc	Protospacer
 . ******.*************.** 

379. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NC_003460 (Propionibacterium phage B5, complete genome) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
aagggcggcgacggcggccagggcggc	Protospacer
 . ******.*************.** 

380. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NC_023692 (Mycobacterium phage BigNuz, complete genome) position: , mismatch: 6, identity: 0.778

cgcggcggcaacggcggccagggtggg	CRISPR spacer
tcgggcggcaacggcggcgcgggtgga	Protospacer
.  ***************  ******.

381. spacer 41.1|9547674|30|NC_021658|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 6, identity: 0.8

accgtacccatcccctccgcggtcgagctc	CRISPR spacer
atcgataccatccgctccgcggtcgagctt	Protospacer
*.**   ****** ***************.

382. spacer 41.1|9547674|30|NC_021658|CRISPRCasFinder matches to NC_007960 (Nitrobacter hamburgensis X14 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.8

accgtacccatcccctccgcggtcgagctc	CRISPR spacer
acaggtgccatccgctccgcggtcgaggtc	Protospacer
** *   ****** ************* **

383. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to NC_031255 (Gordonia phage Schwabeltier, complete genome) position: , mismatch: 6, identity: 0.8

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
tcccgcgcgacgaccgcggtggccttcttg	Protospacer
************ ** ********   .**

384. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.8

tcccgcgcgacgtcctcggtggccg--agctg	CRISPR spacer
gcccgcgcgacgtcctcggccgccgccagt--	Protospacer
 ******************. ****  **.  

385. spacer 43.1|9915053|27|NC_021658|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 6, identity: 0.778

gccagtgtgacggcgcggcgagctcga	CRISPR spacer
gccagaatgacggcgcggcgagcgtcg	Protospacer
***** .**************** . .

386. spacer 47.2|10090957|29|NC_021658|CRISPRCasFinder matches to NZ_CP017942 (Phyllobacterium zundukense strain Tri-48 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.793

gaggcgctccacgcgcgcctcgctgcgcg	CRISPR spacer
catgcgctacatgcgcgcctcgctgctgg	Protospacer
 * ***** **.**************  *

387. spacer 47.2|10090957|29|NC_021658|CRISPRCasFinder matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.793

gaggcgctccacgcgcgcctcgctgcgcg	CRISPR spacer
gaagcgctccacccgcgcctcgcggtcgg	Protospacer
**.********* ********** *.  *

388. spacer 47.2|10090957|29|NC_021658|CRISPRCasFinder matches to NZ_LN997849 (Magnetospirillum sp. XM-1 isolate XM1 plasmid II, complete sequence) position: , mismatch: 6, identity: 0.793

gaggcgctccacgcgcgcctcgctgcgcg	CRISPR spacer
gagacgctccacgcgcgcctccaagccag	Protospacer
***.*****************   **  *

389. spacer 47.2|10090957|29|NC_021658|CRISPRCasFinder matches to NC_010399 (Clavibacter michiganensis subsp. sepedonicus plasmid pCS1, complete sequence) position: , mismatch: 6, identity: 0.793

gaggcgctccacgcgcgcctcgctgcgcg	CRISPR spacer
gaggcgctccacgcgagcatcgcagatca	Protospacer
*************** ** **** *  *.

390. spacer 47.2|10090957|29|NC_021658|CRISPRCasFinder matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 6, identity: 0.793

gaggcgctccacgcgcgcctcgctgcgcg	CRISPR spacer
gaagcgctccacccgcgcctcgcggtcgg	Protospacer
**.********* ********** *.  *

391. spacer 50.4|10766116|30|NC_021658|CRT matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 6, identity: 0.8

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
tcgaccgccgacttctccgacaccgacgcc	Protospacer
.** ****** **************   **

392. spacer 50.4|10766116|30|NC_021658|CRT matches to NC_013449 (Streptomyces sp. W9 plasmid pCQ3, complete sequence) position: , mismatch: 6, identity: 0.8

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
caggccgccgccctctacgacaccgcggcg	Protospacer
* * ********.*** ********** * 

393. spacer 50.4|10766116|30|NC_021658|CRT matches to JF412299 (EBPR siphovirus 4, partial sequence) position: , mismatch: 6, identity: 0.8

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
cagccggccgccttcgccgacaccggccgc	Protospacer
* *** ********* *********  * *

394. spacer 50.5|10766164|30|NC_021658|CRT matches to KT021004 (Thermobifida phage P1312, complete genome) position: , mismatch: 6, identity: 0.8

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gggtgcgcggcctgctccgacatcgcgcac	Protospacer
* *. ******** ********.***** *

395. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 6, identity: 0.8

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gcgaggccggccttctgcgacaccccgctc	Protospacer
***    ********* ******* *****

396. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.8

gcgc-tcgccaccgccgccggcgcggcgctc	CRISPR spacer
-cgcagcgccaccgccgcgagcgcggcgccg	Protospacer
 ***  ************ .*********. 

397. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgcacgccaccgccgccgacgcggccgcg	Protospacer
**** **************.******  . 

398. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctcgccaccgccgacgccgcgcacctg	Protospacer
**************** ** ****   ** 

399. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LR134455 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 13, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gacgtcgccgccgccggcggcgcggcgctg	Protospacer
*   *****.****** ************ 

400. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ctgatagccgccggcgccggcgcggcgctc	Protospacer
 .* * ***.*** ****************

401. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctggccaccgccgccgtcgcggggtgg	Protospacer
***** ************* ***** *.  

402. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ctgatcggcgccgccgccggcgcggcgctg	Protospacer
 .* *** *.******************* 

403. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcg-cggcgctc	CRISPR spacer
gtgctcgccacggccgccggcgcctacgcc-	Protospacer
*.********* ********** * .***. 

404. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP032704 (Pantoea dispersa strain DSM 32899 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cagatggcctccgccgccggcgcggcgctg	Protospacer
  * * *** ******************* 

405. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_015223 (Nitrosomonas sp. AL212 plasmid pNAL21201, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctcgccaccggcaccggcgcggaagta	Protospacer
************* *.********* . * 

406. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctggccaccgccgccgtcgcggggtgg	Protospacer
***** ************* ***** *.  

407. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tcgggcggcaccgccgccggcgcggcgacc	Protospacer
 **  ** ******************* .*

408. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tcgggcggcaccgccgccggcgcggcgacc	Protospacer
 **  ** ******************* .*

409. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctcgccaaggccgccggcgccctgttc	Protospacer
**********  ***********  .*.**

410. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP023551 (Rhodobacter sp. CZR27 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gaggccgccacccgcgccggcgcggcgctg	Protospacer
* * .*******  *************** 

411. spacer 50.6|10766212|30|NC_021658|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tcgggcggcaccgccgccggcgcggcgacc	Protospacer
 **  ** ******************* .*

412. spacer 50.6|10766212|30|NC_021658|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tcgggcggcaccgccgccggcgcggcgacc	Protospacer
 **  ** ******************* .*

413. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP031079 (Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccccttgccaccgccgccggcgcgggcctt	Protospacer
 * **.*******************  **.

414. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtggtcgccaccgccgccggtgcggccgtg	Protospacer
*.* ****************.*****  * 

415. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP024426 (Paracoccus yeei strain TT13 plasmid pTT13-4, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccccttgccaccgccgccggcgcgggcctt	Protospacer
 * **.*******************  **.

416. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP020445 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed5, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccccttgccaccgccgccggcgcgggcctt	Protospacer
 * **.*******************  **.

417. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP048283 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248c, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgctcgccatcgccgacggcgcggggtcc	Protospacer
 *********.***** ******** *..*

418. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021126 (Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
acgctcggcatcgccgccggcgcggaactg	Protospacer
.****** **.************** .** 

419. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cctttcgcccccgccgctggcgcggcgcgc	Protospacer
 * .***** *******.********** *

420. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP044079 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccccttgccaccgccgccggcgcgggcctt	Protospacer
 * **.*******************  **.

421. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtgatcgccaccgcggccggcgcggccagc	Protospacer
*.* ********** ***********   *

422. spacer 50.6|10766212|30|NC_021658|CRT matches to KT381864 (Thiobacimonas phage vB_ThpS-P1, complete genome) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtgggcgccatcgccgccggcgcggcggta	Protospacer
*.*  *****.**************** * 

423. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_009806 (Kineococcus radiotolerans SRS30216 = ATCC BAA-149 plasmid pKRAD01, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctcgccatcgccgtcggcgccttgatc	Protospacer
**********.*****.******  .* **

424. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP029777 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
acgctcgccacggccgacggcgcgaccccc	Protospacer
.********** **** *******.* *.*

425. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_011143 (Phenylobacterium zucineum HLK1 plasmid, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgc---caccgccgccggcgcggcgctc	CRISPR spacer
---ctcgtttgcaccgccgccgccgcggcgctg	Protospacer
   ****.   *********** ********* 

426. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_011371 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG204, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgatcgccaccgccgccggcacgaggatc	Protospacer
 ** *****************.**. * **

427. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtggtccccaccgccgccggcgcgacggcc	Protospacer
*.* ** *****************.** .*

428. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 6, identity: 0.8

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ggtctgaccaccgccgcctacgcggcgctc	Protospacer
*  ** .*********** .**********

429. spacer 58.1|12836862|31|NC_021658|CRISPRCasFinder matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 6, identity: 0.806

cgtggcgtcgtccgatccggcgctctctccg	CRISPR spacer
cgtggcgtcgtccgcgccggcgctcttcgtg	Protospacer
**************  **********.. .*

430. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 6, identity: 0.778

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
ggccggcgccatcgcggcgatcgcctt	Protospacer
  ******* *****.********* .

431. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 6, identity: 0.778

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
ggccggcacgatcgcagcgctcgccgg	Protospacer
  *****.*********** *****. 

432. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_CP018080 (Sulfitobacter sp. AM1-D1 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.778

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
ccccggcgcgatcgcagcagtcggtcg	Protospacer
******************..*** .  

433. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_KY349138 (Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_2, complete sequence) position: , mismatch: 6, identity: 0.778

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
gccgggcccgatcgcagcgatcgctgt	Protospacer
 ** *** ****************...

434. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.778

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
atcgatcgtgatcgcagcgatcgccac	Protospacer
 .* . **.******************

435. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NC_042348 (Salinibacter virus M1EM-1, partial genome) position: , mismatch: 6, identity: 0.778

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
gatccccgcgatcgcagcgatcgccgc	Protospacer
  .*  *******************.*

436. spacer 7.1|3465111|32|NC_021658|CRISPRCasFinder matches to NZ_CP017944 (Phyllobacterium zundukense strain Tri-48 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.781

cgccacccggccattcaggacacgccacccgg	CRISPR spacer
agccagccggccattcaggccacgctatcgcg	Protospacer
 **** ************* *****.*.*  *

437. spacer 8.1|3493336|35|NC_021658|CRISPRCasFinder matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.8

-gcggcgcctcggcggacggcgcggccggcagcgca	CRISPR spacer
cgctgtg-cgcggcggacggcgcggcctgcggcgcc	Protospacer
 ** *.* * ***************** **.**** 

438. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.774

cccggagctccaggccggcaagatcacgccc	CRISPR spacer
tcctgtgctccaggccggcaagatcatcgac	Protospacer
.** * ********************.   *

439. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NC_008738 (Marinobacter hydrocarbonoclasticus VT8 plasmid pMAQU01, complete sequence) position: , mismatch: 7, identity: 0.774

cccggagctccaggccggcaagatcacgccc	CRISPR spacer
cccggcgctgcaggccggcaagataccgttt	Protospacer
***** *** **************  **...

440. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NC_019917 (Burkholderia phage BcepMigl, complete genome) position: , mismatch: 7, identity: 0.774

cccggagctccaggccggcaagatcacgccc	CRISPR spacer
cgacgagctcgaggccggcgagatcacgatc	Protospacer
*   ****** ********.******** .*

441. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NC_005262 (Burkholderia cepacia phage Bcep22, complete genome) position: , mismatch: 7, identity: 0.774

cccggagctccaggccggcaagatcacgccc	CRISPR spacer
cgacgagctcgaggccggcgagatcacgatc	Protospacer
*   ****** ********.******** .*

442. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.774

cccggagctccaggccggcaagatcacgccc	CRISPR spacer
gtcgaacgtccaggccgggaacatcacgccc	Protospacer
 .**.*  ********** ** *********

443. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.774

tcgac-gcgctcgacgcgctccacgcggtcga	CRISPR spacer
-cgccggcgctctacgcgctgcacgcggtgct	Protospacer
 ** * ****** ******* ********   

444. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.774

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
gggaagcgctcgacgcgctcgacgcggtgct	Protospacer
  ** *************** *******   

445. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.774

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
gggaagcgctcgacgcgctcgacgcggtgct	Protospacer
  ** *************** *******   

446. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_LR134459 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence) position: , mismatch: 7, identity: 0.774

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
aggcggcgctcgacgtgctcgacgcggtcgg	Protospacer
  *  **********.**** *********.

447. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
ccaccgcgctcgacgcgctccgcgcggacac	Protospacer
.*. *****************.***** *. 

448. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_LR134455 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 13, complete sequence) position: , mismatch: 7, identity: 0.774

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
cggagcggctcgacgcgctccaggcggtcgg	Protospacer
. **   *************** *******.

449. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.774

tcgac--gcgctcgacgcgctccacgcggtcga	CRISPR spacer
--ggctggagctcgacgcgatcctcgcggtcgt	Protospacer
  *.*  * ********** *** ******** 

450. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP048816 (Caulobacter rhizosphaerae strain KCTC 52515 plasmid unnamed) position: , mismatch: 7, identity: 0.774

tcgacgcg--ctcgacgcgctccacgcggtcga	CRISPR spacer
--gacacgatctcgacgcgctccacgcgcgtgt	Protospacer
  ***.**  ******************  .* 

451. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 7, identity: 0.774

tcgac--gcgctcgacgcgctccacgcggtcga	CRISPR spacer
--ggctagagctcgacgcgatcctcgcggtcgt	Protospacer
  *.*  * ********** *** ******** 

452. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.774

tcgac--gcgctcgacgcgctccacgcggtcga	CRISPR spacer
--ggctggagctcgacgcgatcctcgcggtcgt	Protospacer
  *.*  * ********** *** ******** 

453. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP024772 (Bacillus thuringiensis LM1212 plasmid pLM1, complete sequence) position: , mismatch: 7, identity: 0.774

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcggtccagtcggtccagtcggtcctggttc	Protospacer
*******.********.******** * .  

454. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.774

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
ctgccccggtcggaccggtcgggccggtcgc	Protospacer
..* .******** ******** ******* 

455. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.774

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
ggggaaccgtcggaccggtcggtcccgtcgg	Protospacer
  **  * ***** *********** *****

456. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NC_018836 (Streptomyces phage phiHau3, complete genome) position: , mismatch: 7, identity: 0.774

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcgggccggtcggaccggtcggtcctgcgat	Protospacer
**** ******** *********** *. . 

457. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.774

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
ccagtccggtcggtcctgccggtccgtcggg	Protospacer
.*.************* *.******* . **

458. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NC_015952 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence) position: , mismatch: 7, identity: 0.774

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
gtgccccggtcgctccggtcgctccggtcgc	Protospacer
 .* .******* ******** ******** 

459. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
gttgcccggtcggtccgggcggtccgggcgt	Protospacer
 . *.************* ******** ** 

460. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.741

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggccacggcggccagcacctc	Protospacer
********* *********** ..   

461. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.741

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggcgacggcggccagttcttc	Protospacer
*********.***********  .   

462. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to CU468217 (Azospirillum brasilense bacteriophage Cd, complete genome) position: , mismatch: 7, identity: 0.741

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggcgacggcggccagttcttc	Protospacer
*********.***********  .   

463. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NC_010355 (Azospirillum phage Cd, complete genome) position: , mismatch: 7, identity: 0.741

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggcgacggcggccagttcttc	Protospacer
*********.***********  .   

464. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.741

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggcgacggcggccagttcttc	Protospacer
*********.***********  .   

465. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP033323 (Azospirillum brasilense strain Cd plasmid p5, complete sequence) position: , mismatch: 7, identity: 0.741

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggcgacggcggccagttcttc	Protospacer
*********.***********  .   

466. spacer 36.3|9128860|27|NC_021658|CRISPRCasFinder matches to NZ_CP033317 (Azospirillum brasilense strain Sp 7 plasmid p5, complete sequence) position: , mismatch: 7, identity: 0.741

cgcggcggcaacggcggccagggtggg	CRISPR spacer
cgcggcggcgacggcggccagttcttc	Protospacer
*********.***********  .   

467. spacer 37.29|9169427|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.806

ccgccggtcgtcgtggtcggcggcgcgcgcgtgcca-	CRISPR spacer
gcgctggtcgtcgtggtcgtcggcgcg-gtgttcctc	Protospacer
 ***.************** ******* *.** **  

468. spacer 41.1|9547674|30|NC_021658|CRISPRCasFinder matches to MN585986 (Microbacterium phage Ariadne, complete genome) position: , mismatch: 7, identity: 0.767

--accgtacccatcccctccgcggtcgagctc	CRISPR spacer
cggtcgt--ccatcgcctccgcggtcgagccg	Protospacer
  ..***  ***** ***************. 

469. spacer 41.1|9547674|30|NC_021658|CRISPRCasFinder matches to MN586007 (Microbacterium phage Smarties, complete genome) position: , mismatch: 7, identity: 0.767

--accgtacccatcccctccgcggtcgagctc	CRISPR spacer
cggtcgt--ccatcgcctccgcggtcgagccg	Protospacer
  ..***  ***** ***************. 

470. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
cgccgcgccacgtcctcggtggccgggtac	Protospacer
. ****** ****************.*.  

471. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 7, identity: 0.767

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
ccccgcgggacgtcctcggtgcccagtccg	Protospacer
.****** ************* **.. *.*

472. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to MT310853 (Microbacterium phage AvGardian, complete genome) position: , mismatch: 7, identity: 0.767

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
gcccgcgcgacgtcctcggcgtcctcggtc	Protospacer
 ******************.* **  * * 

473. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to LR134122 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2) position: , mismatch: 7, identity: 0.767

gccccggagcaggtgctgcaggcgtacgcg	CRISPR spacer
gcgccggagcaggtgctgcagctggtcgaa	Protospacer
** ****************** .*  ** .

474. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to FJ706172 (Propionibacterium phage PAS50, complete genome) position: , mismatch: 7, identity: 0.767

gccccggagcaggtgctgcaggcgtacgcg	CRISPR spacer
gaggcggagcaggtgctgcaggagtctggg	Protospacer
*   ****************** ** .* *

475. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to NC_015453 (Propionibacterium phage PAS50 endogenous virus, complete genome) position: , mismatch: 7, identity: 0.767

gccccggagcaggtgctgcaggcgtacgcg	CRISPR spacer
gaggcggagcaggtgctgcaggagtctggg	Protospacer
*   ****************** ** .* *

476. spacer 47.2|10090957|29|NC_021658|CRISPRCasFinder matches to NZ_CP015372 (Pandoraea pnomenusa strain MCB032 plasmid unnamed 1, complete sequence) position: , mismatch: 7, identity: 0.759

gaggcgctccacgcgcgcctcgctgcgcg	CRISPR spacer
cggcgactccccgcgcgcctcgctgggcg	Protospacer
 .*  .**** ************** ***

477. spacer 47.2|10090957|29|NC_021658|CRISPRCasFinder matches to NZ_CP015372 (Pandoraea pnomenusa strain MCB032 plasmid unnamed 1, complete sequence) position: , mismatch: 7, identity: 0.759

gaggcgctccacgcgcgcctcgctgcgcg	CRISPR spacer
cggcgactccccgcgcgcctcgctgggcg	Protospacer
 .*  .**** ************** ***

478. spacer 47.2|10090957|29|NC_021658|CRISPRCasFinder matches to NZ_CP045095 (Streptomyces sp. GY16 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

gaggcgctccacgcgcgcctcgctgcgcg	CRISPR spacer
caggcgctcgacgcgcgcctcggcctccg	Protospacer
 ******** ************ . . **

479. spacer 48.1|10333345|29|NC_021658|CRISPRCasFinder matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 7, identity: 0.759

ggatgtcggcctgggtcctggggcgcagg	CRISPR spacer
gatcatgggcctgggtcctggggctcagc	Protospacer
*. ..* ***************** *** 

480. spacer 50.1|10765981|30|NC_021658|CRT matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 7, identity: 0.767

ccgccggctgacttctctggaacagcgcgc	CRISPR spacer
gggccggctgcgttctctggaacaggcggc	Protospacer
  ********  *************   **

481. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP034352 (Streptomyces sp. W1SF4 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.767

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggctcggccggcttctccgacaccgcggcc	Protospacer
   .* **** **************** **

482. spacer 50.4|10766116|30|NC_021658|CRT matches to MK113950 (Phage 5P_2, complete genome) position: , mismatch: 7, identity: 0.767

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ttgtccgccgccagctccgacaccgcgcat	Protospacer
..*.********  ************** .

483. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP031754 (Rhodobacter sphaeroides strain EBL0706 plasmid p.C, complete sequence) position: , mismatch: 7, identity: 0.767

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
gagtgcaccgccttcttcgagaccgcgccc	Protospacer
  *. *.*********.*** *********

484. spacer 50.4|10766116|30|NC_021658|CRT matches to GQ919031 (Streptomyces phage ZL12, complete genome) position: , mismatch: 7, identity: 0.767

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
tggcacgccgccttctccgaccccgacctc	Protospacer
. ** **************** ***  *.*

485. spacer 50.4|10766116|30|NC_021658|CRT matches to MN204498 (Streptomyces phage Saftant, complete genome) position: , mismatch: 7, identity: 0.767

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ttgtccgccgccttctccgactcagcgacg	Protospacer
..*.***************** * *** * 

486. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP021408 (Celeribacter manganoxidans strain DY25 plasmid pDY25-D, complete sequence) position: , mismatch: 7, identity: 0.767

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgcccgcggccttctcggtcaccgcaggc	Protospacer
 .*************** * ******.  *

487. spacer 50.5|10766164|30|NC_021658|CRT matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 7, identity: 0.767

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
gaggtcgaggccttctccgaaaccgcgcag	Protospacer
* * .** ************ *******  

488. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgcccgcggccttctccgacaccgcgctc---	CRISPR spacer
acgcccgcgccctcctccgacacc---ttcgag	Protospacer
.******** ***.**********   .**   

489. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctcgccaccgccgacgccgcccacctg	Protospacer
**************** ** ***    ** 

490. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cgtctcgcgaccgccgccggcgccgcccgc	Protospacer
   ***** ************** ** * *

491. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP034911 (Ensifer alkalisoli strain YIC4027 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
agttacgccaccgcctccggcgctgcgctc	Protospacer
.  . ********** ******* ******

492. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015737 (Shinella sp. HZN7 plasmid pShin-01, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
aagctcgccacccccgccggcgcggtcgcc	Protospacer
. ********** ************.  .*

493. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP013426 (Burkholderia sp. MSMB0856 plasmid pMSMB0856, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cgagccgccgccgccgccgccgcggcgctc	Protospacer
  . .****.********* **********

494. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

495. spacer 50.6|10766212|30|NC_021658|CRT matches to LR134122 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tccaacgccagcgccgccggcgcggcgcca	Protospacer
 *   ***** *****************. 

496. spacer 50.6|10766212|30|NC_021658|CRT matches to LR134122 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcccccgccaccgccgccggcgctgaacgg	Protospacer
** *.****************** * .*  

497. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

498. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

499. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

500. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP013855 (Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctcgccacggccgccgccgcgacctgg	Protospacer
*********** ******* ****.* .  

501. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

502. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

503. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

504. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

505. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

506. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctcgccgccgccgccgccgcgcagggt	Protospacer
*********.********* ****  *  .

507. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gacctcgccaccgccgcccgcgcggtggag	Protospacer
*  *************** ******.*   

508. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

509. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

510. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

511. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

512. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

513. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

514. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP054618 (Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gacctcgccaccgccgcccgcgcggtggag	Protospacer
*  *************** ******.*   

515. spacer 50.6|10766212|30|NC_021658|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

516. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP050991 (Chromobacterium violaceum strain FDAARGOS_635 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gacgccgcctccgccgccggcgcggcgggc	Protospacer
*   .**** *****************  *

517. spacer 50.6|10766212|30|NC_021658|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

518. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gacctcgccaccgccgcccgcgcggtggag	Protospacer
*  *************** ******.*   

519. spacer 50.6|10766212|30|NC_021658|CRT matches to MH669000 (Gordonia phage Ali17, complete genome) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tcgctcgccatcgccgtcggcgcgggcacc	Protospacer
 *********.*****.********   .*

520. spacer 50.6|10766212|30|NC_021658|CRT matches to MN586026 (Gordonia phage Leonard, complete genome) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tcgctcgccatcgccgtcggcgcgggcacc	Protospacer
 *********.*****.********   .*

521. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_031112 (Gordonia phage Phinally, complete genome) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tcgctcgccatcgccgtcggcgcgggcacc	Protospacer
 *********.*****.********   .*

522. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP013072 (Sphingobium indicum B90A plasmid pSRL2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ttgctcgccgccgccgccagcgcggccgac	Protospacer
 .*******.********.*******   *

523. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP018096 (Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
agcctcgccatcgcggccggcgcggcggcc	Protospacer
.  *******.*** ************ .*

524. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_AP021845 (Azospira sp. I09 plasmid pAZI09, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgctcgccaccgccggcggcgaggttaac	Protospacer
 *************** ***** **.   *

525. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP024423 (Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
accgccgccagcgccgccggcgcggcgtgc	Protospacer
.*  .***** ****************. *

526. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

527. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gccctcgccaccgcccccggcgcctcccag	Protospacer
** ************ *******  * *  

528. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgctcgccaccgcccccagcgcgcagagc	Protospacer
 ************** **.*****  *  *

529. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtgggtgccatcgccgccggcgcggcgcag	Protospacer
*.*  .****.*****************  

530. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

531. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

532. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP044080 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
accgccgccagcgccgccggcgcggcgtgc	Protospacer
.*  .***** ****************. *

533. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_014035 (Rhodobacter capsulatus SB 1003 plasmid pRCB133, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ctgggcgccaccgcgggcggcgcggcgctg	Protospacer
 .*  ********* * ************ 

534. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KX518743 (Escherichia coli strain HYEC7 plasmid pHYEC7-IncHI2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

535. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KY019259 (Escherichia coli strain YJMC8 plasmid pHNYJC8, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

536. spacer 50.6|10766212|30|NC_021658|CRT matches to AP018456 (Escherichia coli O25b:H4-ST131 plasmid pMRY09-581ECO_1 MRY09-581 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

537. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

538. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP019604 (Croceicoccus marinus strain E4A9 plasmid pCME4A9II, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tcgctcgtccccgccgccggcgcgaacttc	Protospacer
 ******.* **************.  .**

539. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP026492 (Escherichia coli strain HS13-1 plasmid pHS13-1-IncHI2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

540. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP033514 (Vibrio cholerae strain E4 plasmid pVCR94, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

541. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KT988018 (Escherichia coli strain V282 plasmid pEcoV282, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

542. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KX421096 (Salmonella enterica subsp. enterica serovar Indiana strain A3 plasmid pA3T, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

543. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KU341381 (Escherichia coli strain SHP45 plasmid pHNSHP45-2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

544. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KY019258 (Escherichia coli strain LDHF400 plasmid pHNLDF400, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

545. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KT282968 (Escherichia coli strain EC012 plasmid pEC012, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

546. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KX721511 (Salmonella enterica subsp. enterica serovar Typhimurium strain SC523 plasmid pSC523, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

547. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KU043115 (Escherichia coli strain Y5 plasmid pECY55, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

548. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KX254341 (Escherichia coli strain JS-B60 plasmid pECJS-B60-267, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

549. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

550. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015077 (Escherichia coli strain Ecol_448 plasmid pEC448_1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

551. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP035548 (Salmonella enterica subsp. enterica serovar Typhimurium strain YU07-18 plasmid pYU07-18_IncA/C2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

552. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KP453775 (Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

553. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KT334335 (Salmonella enterica subsp. enterica serovar Typhimurium strain ST06-53 plasmid pHK0653, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

554. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_KT990220 (Escherichia coli strain 42-2 plasmid p42-2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

555. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP041338 (Escherichia coli strain CCUG 73778 plasmid pSUH-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

556. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP023850 (Escherichia coli strain 4/0 plasmid p4_0.1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

557. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP035517 (Escherichia coli strain U14A plasmid pU14A_A, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

558. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP048368 (Escherichia coli strain 163 plasmid pC-F-164_A-OXA140, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

559. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
accctcgccaccgccgccggcccgcagtcc	Protospacer
.* ****************** **  *..*

560. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LR130565 (Escherichia coli strain MS14387 isolate MS14387 plasmid 2) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

561. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP042337 (Escherichia coli strain GZ04-0086 plasmid pCTXM-GZ04, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

562. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gttttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

563. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gttttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

564. spacer 50.6|10766212|30|NC_021658|CRT matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

565. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP035478 (Escherichia coli strain U13A plasmid pU13A_A, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

566. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP014493 (Escherichia coli strain MVAST0167 plasmid pMVAST0167_1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

567. spacer 50.6|10766212|30|NC_021658|CRT matches to LR606150 (Rhizobium sp. Q54 genome assembly, plasmid: 7) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tggatcgccaccgccgcctgcacggcgatt	Protospacer
  * ************** **.***** *.

568. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP048331 (Escherichia coli strain 10 plasmid p010_A, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

569. spacer 50.6|10766212|30|NC_021658|CRT matches to KY075659 (Escherichia coli strain GD80 plasmid pGD80-2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

570. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP011136 (Escherichia coli VR50 plasmid pVR50B, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

571. spacer 50.6|10766212|30|NC_021658|CRT matches to LN850163 (Escherichia coli plasmid pI1-34TF, strain I1-34) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

572. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021289 (Escherichia coli strain PA45B plasmid pPA45B, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

573. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP029575 (Escherichia coli strain DA33133 plasmid pDA33133-157, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

574. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP019282 (Escherichia coli strain 13P484A plasmid p13P484A-2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

575. spacer 50.6|10766212|30|NC_021658|CRT matches to MN007141 (Escherichia coli strain 91 plasmid p91_NDM5, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

576. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LS992181 (Escherichia coli isolate Escherichia coli str. TO124 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

577. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LR130556 (Escherichia coli strain MS14385 isolate MS14385 plasmid 2) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

578. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP014496 (Escherichia coli strain SaT040 plasmid pSaT040, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

579. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP013836 (Escherichia coli strain JJ1897 plasmid pJJ1897_1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

580. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP011515 (Mitsuaria sp. 7 plasmid, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gacggctccaccgacggcggcgcggcgctc	Protospacer
*    * ****** ** *************

581. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP019251 (Escherichia coli strain 13KWH46 plasmid p13KWH46-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

582. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021728 (Escherichia coli strain Combat11I9 plasmid pCombat11I9-2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

583. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP006642 (Escherichia coli PCN061 plasmid PCN061p6, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

584. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcggctccaccgccgcctgagcggcgctc	Protospacer
*.   * *********** * *********

585. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

586. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

587. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

588. spacer 50.6|10766212|30|NC_021658|CRT matches to MT077880 (Escherichia coli plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

589. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gacatcgccaccgccgggggcgcggcggcc	Protospacer
*   ************  ********* .*

590. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gacatcgccaccgccgggggcgcggcggcc	Protospacer
*   ************  ********* .*

591. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP041619 (Shigella flexneri strain C32 plasmid pC32_1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

592. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP030770 (Escherichia coli strain 2017C-4173W12 plasmid p2017C-4173W12, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

593. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP019247 (Escherichia coli strain Combat13F7 plasmid pCombat13F7-2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

594. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP019268 (Escherichia coli strain 13C1079T plasmid p13C1079T-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

595. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP019262 (Escherichia coli strain 13C1065T plasmid p13C1065T-3, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

596. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP019244 (Escherichia coli strain Combat2C1 plasmid pCombat2C1-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

597. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP012634 (Escherichia coli strain SF-166 plasmid pSF-166-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

598. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP036244 (Escherichia coli strain S65EC plasmid pS65EC, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

599. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP024718 (Escherichia coli strain LS4 plasmid p1LS4, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

600. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP023845 (Escherichia coli strain 4/1-1 plasmid p4_1_1.1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

601. spacer 50.6|10766212|30|NC_021658|CRT matches to MN577015 (Salmonella enterica plasmid p0085-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

602. spacer 50.6|10766212|30|NC_021658|CRT matches to MN086777 (Escherichia coli plasmid p16EC-p0111, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

603. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP024721 (Escherichia coli isolate NQ3 plasmid p1NQ3, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

604. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015160 (Escherichia coli strain Eco889 plasmid pECO-fce, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

605. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP027130 (Escherichia coli strain AR_0372 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

606. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP014523 (Escherichia coli strain ZH063 plasmid pZH063_1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

607. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP029580 (Escherichia coli strain DA33137 plasmid pDA33137-178, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

608. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP014498 (Escherichia coli strain ZH193 plasmid pZH193, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

609. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

610. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP032877 (Escherichia coli strain WCHEC000837 plasmid pCTXM15_000837, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

611. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_008270 (Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gaactcgtcaccgccgccgtcgcggccggc	Protospacer
* .****.*********** ******   *

612. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP053232 (Escherichia coli strain SCU-306 plasmid pSCU-306-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

613. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP053248 (Escherichia coli strain SCU-482 plasmid pSCU-482-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

614. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP053246 (Escherichia coli strain SCU-485 plasmid pSCU-485-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

615. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP027119 (Escherichia coli strain 26561 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

616. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015740 (Shinella sp. HZN7 plasmid pShin-04, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctcgccgccgccaccggcgcaatgccg	Protospacer
*********.*****.*******...**. 

617. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP038139 (Escherichia coli strain G3X16-2 plasmid pG3X16-2-2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

618. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP034820 (Salmonella sp. SSDFZ54 plasmid pTB501, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

619. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

620. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP010882 (Escherichia coli strain MNCRE44 plasmid pMNCRE44_6, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

621. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015131 (Klebsiella pneumoniae strain Kpn555 plasmid pKPN-7c3, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

622. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP041177 (Salmonella enterica subsp. enterica serovar Enteritidis strain SJTUF12367v2 plasmid p12367A, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

623. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gttttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

624. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gttttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

625. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LT985252 (Escherichia coli strain 666 plasmid RCS51_p, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

626. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP050707 (Salmonella enterica subsp. enterica serovar Enteritidis strain SE124 plasmid pSE124-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

627. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

628. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

629. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP035468 (Escherichia coli strain U12A plasmid pU12A_A, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

630. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP051707 (Escherichia coli strain SCU-124 plasmid pSCU-124-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

631. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LR130563 (Escherichia coli strain MS14384 isolate MS14384 plasmid 2) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

632. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP051701 (Escherichia coli strain SCU-125 plasmid pSCU-125-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

633. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

634. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP051712 (Escherichia coli strain SCU-123 plasmid pSCU-123-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

635. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP051695 (Escherichia coli strain SCU-313 plasmid pSCU-313-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

636. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP051726 (Escherichia coli strain SCU-112 plasmid pSCU-112-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

637. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021690 (Escherichia coli strain AR_0058 plasmid tig00007555j7554, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

638. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP024860 (Escherichia coli strain AR_0014 plasmid unitig_1_pilon, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

639. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP024816 (Escherichia coli strain CREC-629 plasmid pCREC-629_1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

640. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP034832 (Salmonella sp. SSDFZ69 plasmid pTB601, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

641. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

642. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP024153 (Escherichia coli strain 14EC033 plasmid p14EC033f, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

643. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP051736 (Escherichia coli strain SCU-108 plasmid pSCU-108-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

644. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP051715 (Escherichia coli strain SCU-122 plasmid pSCU-122-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

645. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP033353 (Salmonella enterica subsp. enterica strain CFSA664 plasmid pCFSA664-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

646. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

647. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP029113 (Escherichia coli strain AR435 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

648. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_AP022566 (Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gccaccgccaccgccaccggcgcggcctac	Protospacer
**  .**********.********** . *

649. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP042879 (Escherichia coli strain NMBU_W05E18 plasmid pNMBU-W05E18_01, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

650. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

651. spacer 50.6|10766212|30|NC_021658|CRT matches to CP054458 (Escherichia coli strain SCU-103 plasmid pSCU-103-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

652. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

653. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

654. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gaactcgtcaccgccgccgtcgcggccggc	Protospacer
* .****.*********** ******   *

655. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

656. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LT795115 (Salmonella enterica subsp. enterica serovar Typhimurium isolate VNB151-sc-2315230 plasmid p1) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

657. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP024130 (Escherichia coli strain 14EC001 plasmid p14EC001c, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

658. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP011429 (Salmonella enterica subsp. enterica serovar Typhimurium strain YU39 isolate YUHS 05-78 plasmid pYU39_IncA/C, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

659. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP016498 (Escherichia coli strain UPEC 26-1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

660. spacer 50.6|10766212|30|NC_021658|CRT matches to CP054382 (Escherichia coli strain SCU-175 plasmid pSCU-175-3, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

661. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021355 (Rhodococcus sp. S2-17 plasmid pRB98, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccgg-cgcggcgctc	CRISPR spacer
gccctcgccaccgccgccggccgcaaagac-	Protospacer
** ***************** ***.. * . 

662. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP043407 (Escherichia coli strain NMBU-W13E19 plasmid pNMBU-W13E19_01, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

663. spacer 50.6|10766212|30|NC_021658|CRT matches to CP054450 (Escherichia coli strain SCU-488 plasmid pSCU-488-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

664. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_017630 (Escherichia coli UM146 plasmid pUM146, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

665. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

666. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

667. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

668. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP048648 (Escherichia coli strain GW-AmxH19 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

669. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP023550 (Rhodobacter sp. CZR27 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcagccgccacccccgccgccgcggcgccg	Protospacer
**. .******* ****** ********. 

670. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP025677 (Escherichia albertii strain ChinaSP140150 plasmid pEA-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

671. spacer 50.6|10766212|30|NC_021658|CRT matches to AP022368 (Escherichia coli E318 plasmid pE318_IMP6 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

672. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

673. spacer 50.6|10766212|30|NC_021658|CRT matches to MN822124 (Escherichia coli strain 14E509 plasmid p14E509-1FII, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

674. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_HG941719 (Escherichia coli O25b:H4-ST131 strain EC958 plasmid pEC958, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

675. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

676. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP025708 (Escherichia coli strain YDC107 plasmid pYDC107_184, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

677. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP006369 (Aureimonas sp. AU20 plasmid pAU20b, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
accctactcatcgccgccggcgcggcgctt	Protospacer
.* **  .**.******************.

678. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021871 (Escherichia coli strain H105 plasmid pH105, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

679. spacer 50.6|10766212|30|NC_021658|CRT matches to AP022363 (Escherichia coli E303 plasmid pE303_IMP6 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

680. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015914 (Escherichia coli strain 210205630 isolate 210205630 plasmid pSLy2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

681. spacer 50.6|10766212|30|NC_021658|CRT matches to MN823989 (Klebsiella pneumoniae strain 283149 plasmid p283149-FII, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

682. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052879 (Escherichia coli strain C21 plasmid pC21-2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

683. spacer 50.6|10766212|30|NC_021658|CRT matches to AP022361 (Escherichia coli E301 plasmid pE301_IMP6 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

684. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

685. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gggctcgccaccgccaccgacgcggacggc	Protospacer
* *************.***.*****    *

686. spacer 50.6|10766212|30|NC_021658|CRT matches to MF353155 (Escherichia coli plasmid pLZ135-CTX, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

687. spacer 50.6|10766212|30|NC_021658|CRT matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

688. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

689. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP050710 (Salmonella enterica subsp. enterica serovar Enteritidis strain SE109 plasmid pSE109-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

690. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

691. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

692. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

693. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

694. spacer 50.6|10766212|30|NC_021658|CRT matches to AP023228 (Escherichia coli YJ3 plasmid pYJ3-a DNA, complete genome) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

695. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP014110 (Escherichia coli strain FDAARGOS_144 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

696. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021937 (Escherichia coli strain AR_0055 plasmid unitig_3j3rc_linear, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

697. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021937 (Escherichia coli strain AR_0055 plasmid unitig_3j3rc_linear, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

698. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP033632 (Escherichia coli isolate ECCNB12-2 plasmid pTB-nb1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

699. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_008703 (Mycobacterium sp. KMS plasmid pMKMS01, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ctgctcaccaccgccgccggcgagggcatc	Protospacer
 .****.*************** **   **

700. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP050724 (Salmonella enterica subsp. enterica serovar Enteritidis strain SE74 plasmid pSE74-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

701. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gttttcggcaccgccgccggcgccgcgatg	Protospacer
*. .*** *************** *** * 

702. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

703. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

704. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

705. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP048026 (Escherichia coli strain GZEC065 plasmid pTEM1-GZEC065, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

706. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP020117 (Escherichia coli strain AR_0104 plasmid unitig_5, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

707. spacer 50.6|10766212|30|NC_021658|CRT matches to CP054321 (Escherichia coli strain SCU-390 plasmid pSCU-390-1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

708. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP027703 (Escherichia coli strain 675SK2 plasmid p675SK2_B, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

709. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP041629 (Escherichia coli strain PE15 plasmid pPE15-IncF, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

710. spacer 50.6|10766212|30|NC_021658|CRT matches to LC520285 (Escherichia coli HP030 plasmid pHP030 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

711. spacer 50.6|10766212|30|NC_021658|CRT matches to LC520287 (Escherichia coli HP129 plasmid pHP129 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

712. spacer 50.6|10766212|30|NC_021658|CRT matches to LC520288 (Escherichia coli HP223 plasmid pHP223 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

713. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022581 (Gordonia rubripertincta strain CWB2 plasmid pGCWB2, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ggcctcgacaccgccgccggtgcggccaac	Protospacer
*  **** ************.*****   *

714. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

715. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcttcggcaccgcggccggcgcggcgatg	Protospacer
*. .*** ****** ************ * 

716. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_013951 (Klebsiella pneumoniae plasmid pKF3-140, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

717. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP051224 (Escherichia coli strain SCZE5 plasmid pSCZE2) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggcatccaccgccgcctgcgcggcgcga	Protospacer
*** .  *********** *********  

718. spacer 50.6|10766212|30|NC_021658|CRT matches to LC520269 (Escherichia coli A0084 plasmid pA0084 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

719. spacer 50.6|10766212|30|NC_021658|CRT matches to LC520270 (Escherichia coli A0086 plasmid pA0086 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

720. spacer 50.6|10766212|30|NC_021658|CRT matches to LC520271 (Escherichia coli A0140 plasmid pA0140 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ccgcacgccaccgccgccagcgcgatgatg	Protospacer
 *** *************.*****..* * 

721. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NC_007412 (Trichormus variabilis ATCC 29413 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.741

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
cggaggcgcgatcgcagcgatcgatgt	Protospacer
*   ******************* ...

722. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NC_005241 (Cupriavidus necator H16 megaplasmid pHG1, complete sequence) position: , mismatch: 7, identity: 0.741

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
agccggcgcgatcgcagccatcgtgca	Protospacer
  **************** ****.   

723. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_CP039289 (Cupriavidus necator H16 plasmid pHG1, complete sequence) position: , mismatch: 7, identity: 0.741

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
agccggcgcgatcgcagccatcgtgca	Protospacer
  **************** ****.   

724. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_CP047244 (Trichormus variabilis 0441 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.741

ccccggcgcgatcgcagcgatcgccac	CRISPR spacer
cggaggcgcgatcgcagcgatcgatgt	Protospacer
*   ******************* ...

725. spacer 2.7|610878|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 8, identity: 0.778

gccgtggcgctcgcgcttgcggcggcgccgaacgag	CRISPR spacer
ggcgtggcgctcgcgcttgcgacggagctgccggtg	Protospacer
* *******************.*** **.*   * *

726. spacer 8.1|3493336|35|NC_021658|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.771

gcggcgcctcggcggacggcgcggcc--ggcagcgca	CRISPR spacer
gcgcctcctcggcggacggcgcggccctgctggag--	Protospacer
*** * ********************  * ..* *  

727. spacer 26.1|7538323|34|NC_021658|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.765

gcgccgcgcgccgtcccgcaggtcctgagcgcgg	CRISPR spacer
gcgccgcgcggcgtcccgcagatcgaggtcacgt	Protospacer
********** **********.**  *. *.** 

728. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NZ_CP015737 (Shinella sp. HZN7 plasmid pShin-01, complete sequence) position: , mismatch: 8, identity: 0.742

cccggagctccaggccggcaagatcacgccc	CRISPR spacer
accggcgctccaggccggcaagttcgatatc	Protospacer
 **** **************** **.   .*

729. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NC_022050 (Paracoccus aminophilus JCM 7686 plasmid pAMI8, complete sequence) position: , mismatch: 8, identity: 0.742

cccggagctccaggccggcaagatcacgccc	CRISPR spacer
ctcgaagctcgaggccggcaagatcatcgat	Protospacer
*.**.***** ***************.   .

730. spacer 27.1|7992042|31|NC_021658|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.742

cccggagctccaggccggcaagatcacgccc	CRISPR spacer
gttgaacgtccaggccgggaacatcacgccc	Protospacer
 ..*.*  ********** ** *********

731. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
ccaccccgctcgaggcgctccacgcgatcac	Protospacer
.*. * ******* ************.**. 

732. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP016463 (Bosea sp. RAC05 plasmid pBSY19_1, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcgaggcgctcgatgcgctccacgatgctct	Protospacer
**** ********.**********  *..  

733. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_015314 (Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
accgccagctcgacgcgctcaacgcggccgg	Protospacer
 * .*  ************* ******.**.

734. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to LT599585 (Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcccagcgctcgaagcgctccacgccgttcg	Protospacer
**   ******** *********** **. .

735. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_LR134450 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 8, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
ccgacgcgctcgtcgcgctcctcggccgcgg	Protospacer
.*********** ******** **    **.

736. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP027299 (Streptomyces sp. SGAir0924 plasmid unnamed_5) position: , mismatch: 8, identity: 0.742

----tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
agtctc----cgctcgacgcgatccgcgcggtcct	Protospacer
    **    *********** ***.*******  

737. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
cggtcgcgctcgacccgctccactcgggccc	Protospacer
. * ********** ******** *** *  

738. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
acgatgcgctcggcgcgctccacggtggcct	Protospacer
 ***.*******.***********  * *  

739. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP021084 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
ccgaggcgctcggcgcgctccacggcttcct	Protospacer
.*** *******.***********   **  

740. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
cggtcgcgctcgacccgctccactcgggccc	Protospacer
. * ********** ******** *** *  

741. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP042333 (Bosea sp. F3-2 plasmid pB32-2, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcgccgcgctcgacgcgctctaccgtggaaa	Protospacer
*** ****************.**   *  .*

742. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
aaggcgcgcacgacgcgcttcacgcggaagc	Protospacer
  *.***** *********.*******  * 

743. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_LR026982 (Rhodoplanes piscinae isolate Rhod_plasmid plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
agggcgcgctcggcgcgctccaggcggccat	Protospacer
  *.********.********* ****.*. 

744. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to KX853513 (Uncultured virus isolate Rctr41k, partial genome) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
ccgacgcgcccggcgcgctccacgaatacgc	Protospacer
.********.**.*********** .  ** 

745. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_016767 (Erwinia phage PEp14, complete genome) position: , mismatch: 8, identity: 0.742

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
atcaggtgcgcgatgcgctccacgcggtcgt	Protospacer
 . * *.** ***.**************** 

746. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP017574 (Bacillus thuringiensis strain SCG04-02 plasmid PSCG364, complete sequence) position: , mismatch: 8, identity: 0.742

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
tcggtccagtcggtccagtcggtaatgtaaa	Protospacer
*******.********.******   ** ..

747. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 8, identity: 0.742

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
ccggtccggtcggtccggcaggtcgaccccg	Protospacer
.*****************. **** . .* *

748. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 8, identity: 0.742

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
ccggtccggtcggtccggcaggtcgaccccg	Protospacer
.*****************. **** . .* *

749. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
cgggcatcgtcggtccggccggtccggtggg	Protospacer
. **. . **********.********* **

750. spacer 37.28|9169355|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034911 (Ensifer alkalisoli strain YIC4027 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.778

gcgggagttcgaccggctccgcggcgacgcgaaggc-	CRISPR spacer
acgggtgttcgaccggctccgcgacga-gtgcgggtt	Protospacer
.**** *****************.*** *.* .**. 

751. spacer 37.42|9170372|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 8, identity: 0.771

tcagcgtcgacgggacgtcgccgagcagggcgagc	CRISPR spacer
tcatgccctccgggatgtcgccgagctgggcgagc	Protospacer
***   .*  *****.********** ********

752. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to NZ_CP013744 (Streptomyces sp. CdTB01 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
atcggcgcggcgtcctcggtggccgacagc	Protospacer
 .* *****.****************    

753. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to NZ_LR134456 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence) position: , mismatch: 8, identity: 0.733

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
agccgcgcgacgtcctcggtgaccttcgcg	Protospacer
  *******************.**    .*

754. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to NC_022049 (Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence) position: , mismatch: 8, identity: 0.733

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
agcaccgcgacgacctcggcggccgagcgc	Protospacer
  *  ******* ******.********  

755. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to MN585986 (Microbacterium phage Ariadne, complete genome) position: , mismatch: 8, identity: 0.733

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
atcatctcgaagtcctcggtggccgagcgc	Protospacer
 .*  * *** *****************  

756. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to MN586007 (Microbacterium phage Smarties, complete genome) position: , mismatch: 8, identity: 0.733

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
atcatctcgaagtcctcggtggccgagcgc	Protospacer
 .*  * *** *****************  

757. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to MN585980 (Microbacterium phage Gina, complete genome) position: , mismatch: 8, identity: 0.733

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
atcatctcgaagtcctcggtggccgagcgc	Protospacer
 .*  * *** *****************  

758. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to MN586059 (Microbacterium phage Teamocil, complete genome) position: , mismatch: 8, identity: 0.733

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
atcatctcgaagtcctcggtggccgagcgc	Protospacer
 .*  * *** *****************  

759. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to NC_011961 (Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
acggtggaaacggcctcggtggccgagctg	Protospacer
 *    * .*** *****************

760. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to MF344569 (Pseudomonas aeruginosa plasmid p12939-PER, complete sequence) position: , mismatch: 8, identity: 0.733

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
gcacgcgcgacttcctcggtggccaggtac	Protospacer
 * ******** ************..*.  

761. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.733

gccccggagcaggtgctgcaggcgtacgcg	CRISPR spacer
ctcttcgagcaggtgctgccggcgtacggc	Protospacer
 .*.. ************* ********  

762. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.733

gccccggagcaggtgctgcaggcgtacgcg	CRISPR spacer
ctcttcgagcaggtgctgccggcgtacggc	Protospacer
 .*.. ************* ********  

763. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.733

gccccggagcaggtgctgcaggcgtacgcg	CRISPR spacer
ctcttcgagcaggtgctgccggcgtacggc	Protospacer
 .*.. ************* ********  

764. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to NZ_CP021170 (Paenibacillus bovis strain BD3526 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

gccccggagcaggtgctgcaggcgtacgcg	CRISPR spacer
ctaccggagcaggtgctgcagccgctgccg	Protospacer
 . ****************** **.   **

765. spacer 44.1|9972900|30|NC_021658|CRISPRCasFinder matches to NC_022968 (Enterobacteria phage 4MG, complete genome) position: , mismatch: 8, identity: 0.733

gccccggagcaggtgctgcaggcgtacgcg	CRISPR spacer
tcccaggagcaggtgctggaggcgctgacc	Protospacer
 *** ************* *****.  .* 

766. spacer 50.4|10766116|30|NC_021658|CRT matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
agcgccgccgccttcgctgacaccgcgcga	Protospacer
    *********** *.**********  

767. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
acccccgccgtcttctccggcaccgccggg	Protospacer
 * *******.********.******    

768. spacer 50.4|10766116|30|NC_021658|CRT matches to NC_016654 (Rhodococcus phage REQ3, complete genome) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
atcggcgccgccgtctccgacaccgcgacg	Protospacer
 .   ******* ************** * 

769. spacer 50.4|10766116|30|NC_021658|CRT matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

770. spacer 50.4|10766116|30|NC_021658|CRT matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

771. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

772. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP015739 (Shinella sp. HZN7 plasmid pShin-03, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
aactccgccgccttctccgcccccgcgggc	Protospacer
   .*************** * *****  *

773. spacer 50.4|10766116|30|NC_021658|CRT matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

774. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

775. spacer 50.4|10766116|30|NC_021658|CRT matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

776. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

777. spacer 50.4|10766116|30|NC_021658|CRT matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

778. spacer 50.4|10766116|30|NC_021658|CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
tccgccgccgccttctccgccgccgcgagg	Protospacer
.*  *************** *.*****   

779. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

780. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

781. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

782. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

783. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

784. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

785. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

786. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

787. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

788. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP026653 (Streptomyces dengpaensis strain XZHG99 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
agctacaccgccgtcgccgacaccgcgccc	Protospacer
   . *.***** ** **************

789. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
acccccgccgtcttctccggcaccgccggg	Protospacer
 * *******.********.******    

790. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

791. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

792. spacer 50.4|10766116|30|NC_021658|CRT matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggcgccgccgccttctccaacacctcggcg	Protospacer
    **************.***** ** * 

793. spacer 50.4|10766116|30|NC_021658|CRT matches to GU936714 (Synechococcus phage S-CBS2, complete genome) position: , mismatch: 8, identity: 0.733

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
ggtcccgccgcctcctccgccaccgctcag	Protospacer
   **********.***** ****** *  

794. spacer 50.5|10766164|30|NC_021658|CRT matches to MT639645 (Mycobacterium phage PainterBoy, complete genome) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
tggaccgcggtcttctccgacaccgatacc	Protospacer
  * ******.**************   .*

795. spacer 50.5|10766164|30|NC_021658|CRT matches to MN096376 (Mycobacterium phage Lucyedi, complete genome) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
tggaccgcggtcttctccgacaccgatacc	Protospacer
  * ******.**************   .*

796. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

797. spacer 50.5|10766164|30|NC_021658|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

798. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

799. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

800. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

801. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

802. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

803. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

804. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

805. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

806. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

807. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

808. spacer 50.5|10766164|30|NC_021658|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ctgctgccgaccttctccgacaccgcgcag	Protospacer
 .**.  **.******************  

809. spacer 50.5|10766164|30|NC_021658|CRT matches to GU321093 (Haloarcula hispanica pleomorphic virus 1, complete genome) position: , mismatch: 8, identity: 0.733

gcgcccgcggccttctccgacaccgcgctc	CRISPR spacer
ttagctgcgaccttcgccgacaccgcgctg	Protospacer
 .. *.***.***** ************* 

810. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atggcggccagcgccgccgccgcggcgctg	Protospacer
..* . **** ******** ********* 

811. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atggcggccagcgccgccgccgcggcgctg	Protospacer
..* . **** ******** ********* 

812. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cggctcaccaccgccggcggcgcggacggc	Protospacer
  ****.********* ********    *

813. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LR134455 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 13, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ggagtcgacaccgccgccggcgccgcgacg	Protospacer
* . *** *************** *** . 

814. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ctgatcgtcacctccgccggcgcggcggag	Protospacer
 .* ***.**** **************   

815. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccctgccaatgccgccggcgcggcgctg	Protospacer
   *..**** .***************** 

816. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gatgccgccaccgcggccggcgcgccgccg	Protospacer
*   .********* ********* ***. 

817. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccctgccaatgccgccggcgcggcgctg	Protospacer
   *..**** .***************** 

818. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccctgccaatgccgccggcgcggcgctg	Protospacer
   *..**** .***************** 

819. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccctgccaatgccgccggcgcggcgctg	Protospacer
   *..**** .***************** 

820. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccatgccaatgccgccggcgcggcgctg	Protospacer
   * .**** .***************** 

821. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccatgccaatgccgccggcgcggcgctg	Protospacer
   * .**** .***************** 

822. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LR134452 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ctcaccgccaccgccgccggcgccgcggcc	Protospacer
 .  .****************** *** .*

823. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_LR134456 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
accgacgcccccgccgccggcgcggagccg	Protospacer
.*   **** *************** **. 

824. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcggcactgccgccggcgcggtattg	Protospacer
..***** ***.*************...* 

825. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
accgacgccaccgccgccgtcgcggcggcg	Protospacer
.*   ************** ******* . 

826. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccatgccaatgccgccggcgcggcgctg	Protospacer
   * .**** .***************** 

827. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccatgccaatgccgccggcgcggcgctg	Protospacer
   * .**** .***************** 

828. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccatgccaatgccgccggcgcggcgctg	Protospacer
   * .**** .***************** 

829. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcggcactgccgccggcgcggtattg	Protospacer
..***** ***.*************...* 

830. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccatgccaatgccgccggcgcggcgctg	Protospacer
   * .**** .***************** 

831. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccatgccaatgccgccggcgcggcgctg	Protospacer
   * .**** .***************** 

832. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
taccatgccaatgccgccggcgcggcgctg	Protospacer
   * .**** .***************** 

833. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcggcactgccgccggcgcggtattg	Protospacer
..***** ***.*************...* 

834. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_AP018520 (Sphingobium sp. YG1 plasmid pYGP1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tccagcgtcaccgccgccggcgcggcgggg	Protospacer
 *   **.*******************   

835. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP013554 (Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atcttcgccagcgccgccggcgcggagcct	Protospacer
.. .****** ************** **..

836. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP013560 (Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atcttcgccagcgccgccggcgcggagcct	Protospacer
.. .****** ************** **..

837. spacer 50.6|10766212|30|NC_021658|CRT matches to AP021850 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cagctcgccagcgcctccggcgcggccgga	Protospacer
  ******** **** **********    

838. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcggcactgccgccggcgcggtattg	Protospacer
..***** ***.*************...* 

839. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP013565 (Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atcttcgccagcgccgccggcgcggagcct	Protospacer
.. .****** ************** **..

840. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
accgccgccaccgccgccgccgcggcatgc	Protospacer
.*  .************** ******.. *

841. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcggcactgccgccggcgcggtattg	Protospacer
..***** ***.*************...* 

842. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_022061 (Mycobacterium phage KayaCho, complete genome) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ctgctcaccaccgccgcctgcgcggccact	Protospacer
 .****.*********** *******  ..

843. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

844. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcggcactgccgccggcgcggtattg	Protospacer
..***** ***.*************...* 

845. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

846. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcggcactgccgccggcgcggtattg	Protospacer
..***** ***.*************...* 

847. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

848. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

849. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_AP022566 (Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gacgcgaccaccgccgcggccgcggcgctc	Protospacer
*   . .********** * **********

850. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

851. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

852. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

853. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP048284 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248b, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc----	CRISPR spacer
gcgcccgccaccgccgccggc----tgccttgat	Protospacer
****.****************    .**..    

854. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ctgatcgccacctccgccagcgcggcggag	Protospacer
 .* ******** *****.********   

855. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
agccccgccaccgccgccggcatggcgccg	Protospacer
.  *.****************..*****. 

856. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP054026 (Rhizobium sp. JKLM12A2 plasmid pPR12A205, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc----	CRISPR spacer
gcgcccgccaccgccgccggc----tgccttgat	Protospacer
****.****************    .**..    

857. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

858. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

859. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

860. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cggatcgccaccgccgccggggcggttccg	Protospacer
  * **************** ****. *. 

861. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_019957 (Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gtcatggccgccgccgccggcgcggcggca	Protospacer
*.  * ***.***************** . 

862. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cagctcgctaccgccgccggcgccagcgtc	Protospacer
  ******.************** .   **

863. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcggtcgccaccgccggcggcgccgattcg	Protospacer
*** ************ ****** *  .. 

864. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

865. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

866. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

867. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

868. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcgccacggccgccgacgcggtccaa	Protospacer
..********* *******.*****. *  

869. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cggatcgccaccgccgccggggcggttccg	Protospacer
  * **************** ****. *. 

870. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atggcggccagcgccgccgccgcggcgctg	Protospacer
..* . **** ******** ********* 

871. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP030829 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750b, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
tcagtctccaccgccgccggcgcgacggcg	Protospacer
 *. ** *****************.** . 

872. spacer 58.1|12836862|31|NC_021658|CRISPRCasFinder matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.742

cgtggcgtcgtccgatccggcgctctctccg	CRISPR spacer
gctggcggcggccgatccggcgctcgccaag	Protospacer
  ***** ** ************** *.  *

873. spacer 7.1|3465111|32|NC_021658|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 9, identity: 0.719

cgccacccggccattcaggacacgccacccgg	CRISPR spacer
cgccacccggccattcagagcaccatcgtcga	Protospacer
******************..***  .  .**.

874. spacer 8.1|3493336|35|NC_021658|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.743

gcggcgcctcggcggacggcgcggccggcagcgca	CRISPR spacer
ccctcgcctcggtggacggcccggccggcggaccg	Protospacer
 *  ********.******* ********.*  *.

875. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.71

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcgtcgcgcgcgacgcgctccacctccaccg	Protospacer
*** ***** ************* .   * .

876. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.71

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
ccagtcgtctcgatccgctccacgcggtcga	Protospacer
.*...   *****. ****************

877. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP024924 (Sphingomonas sp. Cra20 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcgacgagctcggcgcgctccacaaactacc	Protospacer
****** *****.**********. . *   

878. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP023152 (Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence) position: , mismatch: 9, identity: 0.71

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
ccaacgcgctcaacgcgctctacgcgtggtg	Protospacer
.*.********.********.*****    .

879. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 9, identity: 0.71

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
tcgccgcgctcgacgcgctcgacttccacat	Protospacer
*** **************** ** .   *. 

880. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP006993 (Methylobacterium sp. AMS5 plasmid pAMS5a, complete sequence) position: , mismatch: 9, identity: 0.71

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
agcgcttcctccatgcgctccacgcggtcga	Protospacer
   .* . *** *.*****************

881. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 9, identity: 0.71

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
aagggacgctcggcgcgctccacgaggtctc	Protospacer
  *. .******.*********** ****  

882. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to NC_012848 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132501, complete sequence) position: , mismatch: 9, identity: 0.71

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
gcacagcggtcgggccgatcggtccggtcct	Protospacer
 *.   ******* ***.***********  

883. spacer 33.2|8825343|31|NC_021658|CRISPRCasFinder matches to MF668280 (Mycobacterium phage Phabba, complete genome) position: , mismatch: 9, identity: 0.71

tcggtccggtcggtccggtcggtccggtcgg	CRISPR spacer
agggtcccgccggtccggtcggtcccgagct	Protospacer
  ***** *.*************** *    

884. spacer 37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to KT919973 (Vibrio phage phi-ST2, complete genome) position: , mismatch: 9, identity: 0.75

cacgttcctgatcacgacgacgaagatgctcatcag	CRISPR spacer
cgttagcttgaacacgacgacgaagacgctcatcat	Protospacer
*..   *.*** **************.******** 

885. spacer 37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NC_023568 (Vibrio phage VH7D, complete genome) position: , mismatch: 9, identity: 0.75

cacgttcctgatcacgacgacgaagatgctcatcag	CRISPR spacer
cgttagcttgaacacgacgacgaagacgctcatcat	Protospacer
*..   *.*** **************.******** 

886. spacer 37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to KT919972 (Vibrio phage phi-Grn1, complete genome) position: , mismatch: 9, identity: 0.75

cacgttcctgatcacgacgacgaagatgctcatcag	CRISPR spacer
cgttagcttgaacacgacgacgaagacgctcatcat	Protospacer
*..   *.*** **************.******** 

887. spacer 37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to MK568540 (Vibrio phage ValB1 HC, complete genome) position: , mismatch: 9, identity: 0.75

cacgttcctgatcacgacgacgaagatgctcatcag	CRISPR spacer
cgttagcttgaacacgacgacgaagacgctcatcat	Protospacer
*..   *.*** **************.******** 

888. spacer 37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to KP671755 (Vibrio phage ValKK3, complete genome) position: , mismatch: 9, identity: 0.75

cacgttcctgatcacgacgacgaagatgctcatcag	CRISPR spacer
cgttagcttgaacacgacgacgaagacgctcatcat	Protospacer
*..   *.*** **************.******** 

889. spacer 37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to MT612989 (Vibrio phage vB_ValM_R11Z, complete genome) position: , mismatch: 9, identity: 0.75

cacgttcctgatcacgacgacgaagatgctcatcag	CRISPR spacer
cgttagcttgaacacgacgacgaagacgctcatcat	Protospacer
*..   *.*** **************.******** 

890. spacer 37.22|9168915|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to MT612988 (Vibrio phage vB_ValM_R10Z, complete genome) position: , mismatch: 9, identity: 0.75

cacgttcctgatcacgacgacgaagatgctcatcag	CRISPR spacer
cgttagcttgaacacgacgacgaagacgctcatcat	Protospacer
*..   *.*** **************.******** 

891. spacer 37.29|9169427|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

ccgccggtcgtcgtggtcggcggcgcgcgcgtgcca	CRISPR spacer
gcactcgtcatcgtcgtcggcggcgcgcgcgtcctc	Protospacer
 *.*. ***.**** ***************** *. 

892. spacer 37.29|9169427|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to MK686071 (Streptomyces phage Mischief19, complete genome) position: , mismatch: 9, identity: 0.75

ccgccggtcgtcgtggtcggcggcgcgcgcgtgcca	CRISPR spacer
gcgccggtcgacgtgttcggcggcgcgtggaaggct	Protospacer
 ********* **** ***********.* . * * 

893. spacer 37.42|9170372|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031163 (Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdI, complete sequence) position: , mismatch: 9, identity: 0.743

tcagcgtcgacgggacgtcgccgagcagggcgagc	CRISPR spacer
gcctggggaacggggcgtccccgagcagggcgagc	Protospacer
 *   *  .*****.**** ***************

894. spacer 37.42|9170372|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049837 (Gordonia terrae strain RL-JC02 plasmid pPAE01, complete sequence) position: , mismatch: 9, identity: 0.743

tcagcgtcgacgggacgtcgccgagcagggcgagc	CRISPR spacer
cctccaggggcgggacgtcgcggagctgggcgagc	Protospacer
.*  *.  *.*********** **** ********

895. spacer 37.42|9170372|35|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020372 (Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs485, complete sequence) position: , mismatch: 9, identity: 0.743

tcagcgtcgacgggacgtcgccgagcagggcgagc	CRISPR spacer
tggtcatgatcgggatgtcgtcgagcagggcgagc	Protospacer
* . *.* . *****.****.**************

896. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 9, identity: 0.7

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
gggcgcgcgacggcgtcggtggccgatact	Protospacer
   ********* * ***********  . 

897. spacer 41.2|9547731|30|NC_021658|CRISPRCasFinder matches to NZ_CP009113 (Rhodococcus opacus strain 1CP plasmid pR1CP2, complete sequence) position: , mismatch: 9, identity: 0.7

tcccgcgcgacgtcctcggtggccgagctg	CRISPR spacer
atctccgcgacgtcctcggtcgccgacgac	Protospacer
 .*. *************** *****    

898. spacer 50.4|10766116|30|NC_021658|CRT matches to CP054922 (Streptomyces sp. NA03103 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
agtaccgccgccttctgcgacagcgcggga	Protospacer
    ************ ***** ****   

899. spacer 50.4|10766116|30|NC_021658|CRT matches to CP054922 (Streptomyces sp. NA03103 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
agtaccgccgccttctgcgacagcgcggga	Protospacer
    ************ ***** ****   

900. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP020556 (Streptomyces sp. Sge12 plasmid pSGE, complete sequence) position: , mismatch: 9, identity: 0.7

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
gtcgacgccgcgttcaccgacaccgcgcat	Protospacer
 .   ****** *** ************ .

901. spacer 50.4|10766116|30|NC_021658|CRT matches to NZ_CP009572 (Sphingomonas taxi strain ATCC 55669 plasmid STP1, complete sequence) position: , mismatch: 9, identity: 0.7

ccgcccgccgccttctccgacaccgcgccc	CRISPR spacer
agcttcgccgccttcgccgacgccgcgcag	Protospacer
   ..********** *****.******  

902. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP022549 (Sphingorhabdus sp. YGSMI21 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
cagctcgccaccgccgccggtgcgagcaag	Protospacer
  ******************.***.     

903. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 9, identity: 0.7

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atcggagccatcgccgccggcgcggcgcct	Protospacer
..    ****.*****************..

904. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 9, identity: 0.7

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
atgctcaccaccgccgccggcacggtcaag	Protospacer
..****.**************.***.    

905. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 9, identity: 0.7

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ctggccgccaccgccgccggcgccgccgct	Protospacer
 .* .****************** **  ..

906. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 9, identity: 0.7

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
attgacaccaccgccgccgtcgcggcgcgg	Protospacer
..   *.************ ********  

907. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP021355 (Rhodococcus sp. S2-17 plasmid pRB98, complete sequence) position: , mismatch: 9, identity: 0.7

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
attgacaccaccgccgccgtcgcggcgcgg	Protospacer
..   *.************ ********  

908. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.7

gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
gcgctcgtcaccgccgcccgcgccatcaag	Protospacer
*******.********** **** ..    

909. spacer 58.1|12836862|31|NC_021658|CRISPRCasFinder matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.71

cgtggcgtcgtccgatccggcgctctctccg	CRISPR spacer
gctggcgtcgtcctttccggcgctctgcggc	Protospacer
  ***********  *********** .   

910. spacer 58.1|12836862|31|NC_021658|CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 9, identity: 0.71

cgtggcgtcgtccgatccggcgctctctccg	CRISPR spacer
gctggcggcggccgatccggcgctcgccaga	Protospacer
  ***** ** ************** *.  .

911. spacer 58.1|12836862|31|NC_021658|CRISPRCasFinder matches to NZ_CP018077 (Sulfitobacter sp. AM1-D1 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

cgtggcgtcgtccgatccggcgctctctccg	CRISPR spacer
agtggcggcgtcccatccggcgctggagatg	Protospacer
 ****** ***** **********     .*

912. spacer 2.52|614173|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023158 (Xanthomonas citri pv. malvacearum strain AR81009 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.722

atcgcgcaggccgcgacgggcggcgccgccacggcc	CRISPR spacer
gctgcgcaggccgagacgggcggcgcagcaatgcag	Protospacer
...********** ************ ** *.*   

913. spacer 2.57|614541|38|NC_021658|CRT matches to NZ_AP014810 (Methylorubrum populi strain P-1M plasmid pMPPM01, complete sequence) position: , mismatch: 10, identity: 0.737

cgttgacatgtcggtcgcggccggcgtcgcccagcgat	CRISPR spacer
aaaggcgatgtcggtcgcggccgggatcgcccagccgt	Protospacer
 .  *  ***************** .********* .*

914. spacer 31.8|8416211|35|NC_021658|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.714

gcactgcgtttgcactgctcgatcatgcgtctgaa	CRISPR spacer
gcgacctcgttgtactgctcgatcgtgcgtctgac	Protospacer
**. . .  ***.***********.********* 

915. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NZ_CP013419 (Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence) position: , mismatch: 10, identity: 0.677

tcgacgcgctcgacgcgctccacgcggtcga	CRISPR spacer
cgtgcgcgcgcgacgcgctccgcgcggcttg	Protospacer
.  .***** ***********.*****.. .

916. spacer 37.29|9169427|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.722

ccgccggtcgtcgtggtcggcggcgcgcgcgtgcca	CRISPR spacer
cgcgaggtcgtcgtgcgcggcggcgcgcgcggcacg	Protospacer
*    **********  **************   *.

917. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 10, identity: 0.667

gcgctcgccaccgccgccggcgcggcgctc---	CRISPR spacer
---cccgccgccaccgccgccgccgcgccgccg	Protospacer
   *.****.**.****** *** ****.    

918. spacer 50.6|10766212|30|NC_021658|CRT matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 10, identity: 0.667

---gcgctcgccaccgccgccggcgcggcgctc	CRISPR spacer
ctatcggccaccgccgccggcgccgcggcg---	Protospacer
    ** .*.**.****** ** *******   

919. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_CP048424 (Rhizobium daejeonense strain KACC 13094 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.63

ccccggcgcgatcgcagcgatcgccac----	CRISPR spacer
----gcggcgatcgccgcgatcgtgccggtc	Protospacer
    *  ******** *******.  *    

920. spacer 59.1|12863912|27|NC_021658|CRISPRCasFinder matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 10, identity: 0.63

ccccggcgcgatcgcagcgatcgccac----	CRISPR spacer
----gcggcgatcgccgcgatcgtgccggtc	Protospacer
    *  ******** *******.  *    

921. spacer 2.52|614173|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018048 (Pseudomonas aeruginosa strain DN1 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.694

atcgcgcaggccgcgacgggcggcgccgccacggcc	CRISPR spacer
caatagcaggccgcgactggcgccgccgccaatacg	Protospacer
     ************ **** ********  .* 

922. spacer 2.52|614173|36|NC_021658|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP015030 (Pseudomonas putida strain KF715 plasmid pKF715A, complete sequence) position: , mismatch: 11, identity: 0.694

atcgcgcaggccgcgacgggcggcgccgccacggcc	CRISPR spacer
caatagcaggccgcgactggcgccgccgccaatacg	Protospacer
     ************ **** ********  .* 

923. spacer 33.1|8825289|31|NC_021658|CRISPRCasFinder matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 11, identity: 0.645

tcgacgcgctcgacgcgctccacgcggtcga---------	CRISPR spacer
---------tcgacgcgctcgacgcggtcaacagtgagat	Protospacer
         *********** ********.*         

924. spacer 50.6|10766212|30|NC_021658|CRT matches to NC_020275 (Mycobacterium intracellulare subsp. yongonense 05-1390 plasmid pMyong1, complete sequence) position: , mismatch: 11, identity: 0.633

gcgctcgccaccgccgccggcgcggcgctc---	CRISPR spacer
---ctcatcgccaccgccggcggcgcggccggc	Protospacer
   ***..*.**.*********  *** .*   

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	3821356 : 3869024	34	Virus_Rctr16k(20.0%)	protease,integrase,plate,tail	attL 3821938:3821955|attR 3868187:3868204
DBSCAN-SWA_2	7627900 : 7712487	55	Salicola_phage(12.5%)	protease,plate,tail	NA
DBSCAN-SWA_3	11179203 : 11248868	53	Tupanvirus(33.33%)	transposase,tail	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_021658|3821356:3869024|DBSCAN-SWA
CTCAGTTGCCCGGATCCACGCAAGCGACCGCGCCGGTCCCGTCTTGCCCGCAGGCTTGGTCGAGCAGACTGCAGTCGGTCTTCGTCACCCGGCGCGGCCCCTCGTCGAGCGCCGTGCAGCGCTTGGCGGTACGACCCTCGCAAACGCCGTCGATCTTCGTGTCGCCGCAGGGATCGGACCAGGTGCTCGCCTTCTTCGCGAACGCGAGCACCTCGGGGCCGAGCGTCGCGTAAACGGCCCCGTAATCGCAGGCGAGCTGGTTCGTCGAAATCACGCCGGAGGCCACGCCGTAGACGCGCAGCCTACCGCCCTCGATACGCACGAGCGGGCCACCCGAGTCGCCATGACAAGGCTGCGCGTCGCCTTCGCCGGCGCCCACGAGAGCCTCGTACCCGGCGAGCAGGATCGCCTCGTCGTACTTGCGGAGCAAGCAATCGATATCGCACGCCGCCTCGCCTTCGTTGCCCTCCTCCTCGGTTTCGGCCGAAAGATGGGCGAGGAGCTCGCTGCGGTCGCGCGTCGTGGCCCATTGCTTGAATGCCTCGAAGCTGCCGAATATCAGCTCGAAGACCTTACCTTCCCGCGCGCGCAGGGTCACGCTGCCCGCCTTGCGCGTGCCGAATGTTTTTTTGTTGTCCTGCACGCCATAACCGATGGCCGCGAAGCGCGTGTCGATGTCGGCGTCCGAGAGATCAGCCATCGCGGCCGGCTCGATGTCGGTGATCTCCTCGTCGAGGTGGACGACGCCCACGTCCCGACCGAAGCCCACGGAGCCCCCTTCATGGCCGGGCGCCCGGCCGAGCTCTACGATATCGACCGTACGGTCGGGGTGGGTTCCGTCGAAACCCACGCCGAAATACACGCGGCCCCCCGCGGCCATCTTGCGCGCGGCGTCGACGCAATGTTTCGCGGTGAGGACGGTCGACTTGCCGATCAGGGCGCCGGAGCAAAAGGGGCGGTATTGCACGTCGAGGGCGCCGGTCTCCTCGCTCGCCGCCTCGACGGCGACGCCGAGGCTGCCGATGGCGCCGAGGGCGTCGCTCTTGGCGTCGACGCCGCCGATGATCGCCTGAGAATCGGCGGCGTCGCTCTCGTCGCCGCCCTCCACCGGCGCCGCGCTGCAAGCAGGCAGGAGGCTCGAGGCTGGGAGTCCAGCGAGGAGGAGGCCGAGACGAAGTCTCGAGATGGTAGGCATGAACACTGGATTCCTTTTCGAGAAGATGGTTTGCGCCGCGACGGCGTGCCCGCGCGATGAGCACTCGTCGTGCCAGTCGTCTCCTCGGGCGGCCCGCGGATCTCTCGCCTCGTATTTCCCCGGCGGCCGAGCCTTCGAGCCGACCCTTGCGTGGTCGAGCAACGGACTGCTCGACGGCCATCCGGAGCGCCCCGCGAAGGATCTCTTGCGCACGGCGCTCCGCGCACTCCGGCAGCTCCGCGCCCGCCCCGAGCGCCGCCTCGCCCGCCCGAGCGCGTGCGCCTCGCTGATCGCCTCGCACGTAGAAAGAGATCTCGCCCGCGCGCGCAGCGCTCGGCGCCGCGCCCCCTCGCGTGCGGGAGTCTGGATGGACTGCGATGCTGGGAACGTCAAGCGCGACGACGGCCGCTCGTCCGGCTCGCGAAGCCGCGCTCGGCTCTCCGCTCCCCGGGGCCGACGCCGAGGCGGCTCCGGGGTTGTCGCGCGGGCGCTGCGGATTACGCTCTCACGGCGGACACCGGGACATCGGATCGTGCTGCTCGCGAGCTACAACCACCTGGATCCCGTGATGTCGTCGCTCTTGGTGGATGTCGTCGCGACGGCCGGCCTCCTCGCCCTCGCCGTCCTCGCGCTCCGGCTGTCGCTCCGGCTGCGCCGCGCCACCGCGCTGGCCGACGCCTCGTTCAGGGCCAACGTCGCGCTCGGGCCCGGCGAGGGCGTCGTCCTGGGTACCGTCGAGCGGGAGCAGGGCGCCGACGTCGCCGTGCGCGTCGAGGTCGAGCAGAAGGGGGTCGAGCTCGCGAGCTCCGTCAGCTGGAGGCACGGGGGGGCCGTCAGCTGGAGGCACGCGTGGACCGAGACCGGCCGCAAGGTCCGCGCCCACCCCTTCTACCTCCGCCACGCCTCCGGCGCTCGCGTCCGTGTGGAGCCGGGCGAGGACGTGATGCTCGTCGACGCGCTGGACGGCATGATCCTTGTCGATCGCACGAAGCGCGTCCGCGTGGCCGAGCTCGTGCCCGGCGAGGAGGCCTTCGCGTTCGGCGAGCTCCGGCGCGCGCCGGATCCCGAGGCGCCTCCCCTGGGGTACCGCGAGAGGGCGCAGGGATACGTGCTCGTGCGTCCGCGCAGGCGGCGCATGCTCCTCTCGTCCGAGCCGTTCGGAGAGCAGTTCGCGCGCAAGGCAGCGTTCCGCCTGCGGTGGGCCATCATCGCGGGCGTCGCGTCGCTCGCGTTCAACGCCGCGTTCGCGCCCTTCCACGCGCGCCGCTGGCTGGGGGAGACGGTGGAGGTCCGCGTGACGCAGCTGCGGGAGAGCGATGACGACCGCGGCAGCTTCGACGTCACGATGCTGGGCCCTCACGGTGTCGCCTTCTCGGACGAGGTTCCTATACCGACGTCGACCGGGTCCGCGGGGGCGGGCGACTGTTGGAGGCGCGCTACGTCCCGTCGTGGCCGTCAGCCAGCACGATCGGCCCCGACGTGACGGCCCATTCCTTCGCCTACGTGGCCTTGCCGCTCTTCGGCGTCATCGCGATCGCCTACTTCTTCCGCGCGCACGCCGCGCTACCCTGGTACGAGAAGAAGCTGATCGAGCACGGGAGCGGCCGGCTGGCCGAGAGCGAGTCGACCGCGTGGGGGGACCAGGAGCGCCCGGAAGGGGACCCGCGGGAACCCGCCTCCGGATGATTCATGATCCGGGAGCTTGGGCCCATCGGTCGCGAGCGACCGCCGGGCCCTCGGCGCGCGGTGCCTGTGGCTCGGCTTGTTCGCCGAGCTTTCTGGCGACCGCTCCGCTCCGACCGAGAGTTCCTGGCGGTATTTCCGTGCGGATGCGGGGCGAGCAGAAGAAAAATCAACCATTTCAATCGGTTCCGGCTGCTCTGCTGCCGCGGTAGGCGCCGGTGTGGCCCAACGCGGGCCCAACGCGGCCCCGTCGGCCGCCGCTTCGTCTTCTGCCGCCGAGGCAGCCGGTACGTCGGCCGATGCCGGCGTCTGGCCCGGAGGCGCGGCTCCCAGGAAGCGGCCTTCGCCCGCCGCCCCAGCCTCCGCTCCTTCCGACAGGCGAGCGCCTCCGACCGCTCGGCCCTTGCCGCGCAGCTCGGGGATCGCTTCATTAAGGGGCGCGAAGTCTCCCAGGCCGAGCTCCGCGACCTTACGTGCGGCGCGCTTGTAGTTATGGATCTGGTTGCTCGACCTGTGCCCGGTCCGATCGGAGATCCACGTCTCGGTGCGCCCGTTCGCTAGCTTGATGGTGATGAAGGTCGCGCGAGTGTCGTGCAAGCGAATGTTCAACCTAGATTCCGTGGTCTCGAACAGTTCAGGCCTTTCGATACCGGCGCAACGCAGGTGATCTCGAAAGCTCTTCGCCCCATCACGACCGGGTAAGGGTAGCCCGCTTGGCCTGGAGAAGACACGCTGCTTTGGGGGACACATCGCAAAGTAGACGCGCAGCGCGCGCACGACATCGGGCGAGAGCGCCCAGGCGCGCGGGTCATCGGTCTTGTTCTCGTCAAGAACTACGGCGCCTCGATCGAGATCCAGATCAGACGGCTCCAGCCTGCCAGCCTCGTCTGCACGCATCCCCTCACGGATCAGAAACCCATAATATATCCGATAAGACAGTGGAATATCCACCGCAGCCATGAGGCGCCCATCCTCGTCGGGATAAAGTGAGCTTTTGGCCTTGTTGTTGTCCGCCTTGGGAACCCATCCACGTGGCAAGGGATTGTTGGCGATGATACGCGCCGGATAGGTCGCGAGCGCGAGTATCCGGTGAATAACTTTTGCGATGCCTTGACGCGAAGAAGCCTCAAGATGTCCCGGCGGCATGGAGACTGCGCTATCCGCGTGATCGACCGTGACGCGAGGAAGAGGGACGGGGCCGAGCACTCCCAGAACATGATTCAGCTTATGTCGGTACTGTTCCGGATGTCGAAGTGCTTTCACATGCAGCGGGTACTGCTCGGCAAGCTGGCCAGATAGCACCCGCTCAGCGAACTCGGCGAAGGTGGTGTCCCCGGATGAGCGGGGACGCGCCTCGCCCTTGCACAGGTGGTCAATCGCGAGCCGGACATCGCGGAGCGCGGTCCCCTCGCGCGCGGCGGCCTGCTCCAGCAGCGGCACGCCGATCACGATCTGCCCGGCGGCGAGCAGGCGCCCGGCGAGCTCGGACAGCACCTCCAGCCGTCCGTTGGCTTCTTGCTCAGTCCGGCACGTCGGCAGGCTGAACGTACGTCGCCCGGCATCGCCGAGGCTGAGGCGTGCGGTCCACGTCCTCCCGCGCAGCCGCACGGAGCCGGAGCCGTTGGCGCGCTTCTCTCCTGCTGCGCGGGCTGTCGGCTTCGGACGTTGCGTCGGGCTCGCCAAGTCTCGCGGGCCCGCGTCGGATGCAGCTGCCTCCGCGGGGAGCGAGGGGCGCCCGGCAGAGCGGCTCCGCCGCGTGCGCCGGTCGGTCGATGCGGGAAGGGATGCTGAAGGGATGGCAGGCGAGCGCTTGGCACCCGCCCGCCTCTGCGGTACGTCGGTCATGGATCGGTCTCCGGTGATGCGGGGGTCGATCAAGGGCTCGCCCGGCGTTCGAGCGCCGAGCGGGCCCGCTCTACTTCTGCGGCAACCTACCACGGCTCGCGGCATCGCGAGGAGCGCTCGCTCGGCCAGTGCGCGGACACGGGACTGGTTCGAGGCCGGCGGTGGCGAGGACTGCGGCAACCCGCGTACGCTCCTCGGCCTCTGCATCGCGGCGCGACGCCGGCTCCTCGGCCAGCGCCCGCAAGTAGGCAACGAACGCCTCGCGCGGGACCAGGCGCAGCTTGCCGAGCTTGGTGACCGGCAGCGGGAAGCCCGGCGCGCGGATCGTATCGAGGAAGACGCGTGCCGGGATCCCGGTGACCGACTCGACGTTCTTCTGCGAGAGCATCTCGGGCGGCGGCGCCGTGATCGTGAGCCCGTCCAGCGGGATCGCAAGCGTCGCGGAGGCTGTCGCCGTCGCGGGCTGGTCGGTCACCTTGCGGCCGAACCGTCCGCGGGCAGGTGTCTCGAGGACCTGAGCCTGGACGGCGAGCATGCCGCTGTCCGCCTGACGCAGAGCAAGCTGTGTCGATGCACGCGCGAGCGCTGCTCGTGCCATGCCTTACCTCCATGCGTTGTGGGTTCCTGAGCAACCGTGACCGACGCCGCCGGAGGAGGCCCGAAAAGGTAGTTCTGCGCCAAAGGTAGTTCGACGCGAGATACCCTTGTAGGCTCGTCGGGCAAACCGTTGGCGAGTCGGGGGGTTAGGTGTTCTGGCAAGCGCCTCCGAGGGGCCGAAAAGCGGGGTAAACGAAGGGGTCAATTGGGTAATTCTGAGCGCCCCCTCGGCGCCCCCGCGATCGGCGCGTCGGGCAGACCGTTACCCGCGCGCCCGCATCGAGACGCGCCATGACGAGCAGGATCTCGTCGCGACGCGTCCGCCGCGTCGGTGTAGGACGCCCAACCACCTCAGTACGGAAGATCGTCAACCGGCCGACCCGCGGCGCGCTCTCAACGGTCGTCGGCTCGTCCTCGGCAGCCGTCGCGGTCGTCCCGTCGGCGGCCGACATCCCGCCTGCGGGCGCCGCCTTGACGGCCCGCGGCCGCGGTACTTCCCGCGATGACGTTGGTGACCGGGACCTCGATGGCGAGCGGAAGAGCCTCGTTCGCCTGCGCCTCTTCGAGGGCGACGACGAGATCGGATTTGGATGCGCTCGACAGGCCAGCATCCGTCGGGAGCGAAAGACTACCAGCCATAGACGGCCTCCTTCGGTGATGTCCGGTGTCCGAACATCCGTGGCCGAAGTCTAGCGCGCCCGCGGAGCCCGCTTTTACTTTGTACTCTATGGATGCTGTACTCTACCGTAGAGTACACGTCCGGGGCCGCGTCGGTTTCCCGTGGAGAGTCGCGGTGCTATACTTGGCTCTGCCTATGCCGAGGCGTCGCGACAAAATGTACTCCACAGCGGTTGCCTGGGTACGGTCGGATCCGCGCGTACGGGCGCCGCTCAGCCGCTCCCTCAGGAGCGACGAGCGTCGGATTGCTGCGCTCGGGGACACCTGGGGGGCGCCCTCGATGCGCTCGGCGCGCCGTACTACCTGGTCCGATGGGTCGCCGGCCCTAAGCTGAGGGACGTTGAGGAGCGTGAGCGCCGCTACCGCGCGTGCGAGGCACTCCGGCGCGAGGTGCCGTGGACCCTGGCCGCTTGGCGCGCGCTGACGGCCACCGAGCGACCGATTCGGCCGGCGGCTCCGAGGCACCGGCTGCGGTCGCTGTCGGTTTCTGTCGAGCCGGCACCGCCGGCCTACTCCGATCCCGGAGCGTCCTGAGAGAGCCGCTACGACGTTGATCGAGCAGGCGCGGCTGGCCGCTAGGGACGACGGGACGAGCCGGTCTCCTGCTCAGGGAACCGAAGCGTCTCGGCCTGCGTGCCGTCCTCCCCCGTTATCGTGCCGTGATCGTGATTCCAGCTGATGCCGCCCTTCCCGGCGGACCGAGCTCGCCATCGGCCCAGGGCGCGCGTTCGAAGAATCGGCGAGGAGGCGAGTGCGCCGCCTCTACTCAGGGAAGCGCTGCGTCTCGACGGCGATGCCGTCCTCGCCCGTGATCACCTCGCCAGACCACTCCCAGCTCGTGCCACCTGGGCCCGGCAGCCCCAGCTCGAAGGTGACCCCCTCCAGCGTGAGCTGATCCTCGTCGAGGTGGGCGATGCCGATCGAGTCGCCGCCGCGCCCGGGGCCGCCGTCGCCTCCGGGGCCGCCGCTGCCACCCTGGCAGGACCACATGCCGTCCCCCAAGGCGCCTCCTGGAGCGCCTCGGCCGGCCTTGCCGCCTTCCTCCGGCAGCCCGCCGTCGCCTCCTGGGCCCCCGTTGTCGCTGGTGATGATGCTGTCGCGCACCGTCACCTCGGCGTGGAGCGCCAGGATCGCGATGCTCGGCTGGCCGTTCTCGCCCCCTCGGCCGCCTCGCCCCCCGCAACCGCCCGCGCCTCCGGAGCCGCCGCCGGCACCCCCCTTGGTGGTCACGCCGCACACCGCGAGCCCACCGCGACGCCCGCCGCCCCCGCCACCGCCTTGGCCCGGCATCCCCCGGGCGCCGTCGCCGGCCCCGTCGCCGTGCCATCCGGTCTCATCAATCCGCCCGCGGCCCTTTCCCGCTGCGCCGGCGGCGCCCCACATGCCGCTTTTTCCGGTGGCGCCGCTGTCGCAACCACCGTCTGCCCGGTTGCCACGTCCTCCATCCCCCGCGAGGTTGGGGGTCGGCTCGGGTACGGGCTCGCCGTCCTCCCCATCTCCAGCGCCGTCGGCGAGCCCGTCACCTCCCTTGCCACCTACGCTCGGAATCCCTCCCTCGCAGGAGTTCACCGCCCGAGCCCCACCCACGACCATCGCTGCGGAGCACGCGTCTCCCCCATACTGCCCGTCCGGCCCCGACGCTGCCCGGCCCGGCCATTTCTCCCCATCGCGGCCCCCCCTCCGTAGTCGGCTTCGATCCAGCTTCCGGTGATCTCCACCGCGGCGCCCGACTGAACGATGATCCCGACATGCGTTGAACTGCGGAGGCGCACGTGATCGATGATCGAGACCCCGTCCGCTGCCCCCGTGTCGCCGGCGCGGGCTGGCTCGACGATCAGCGCGATCTGCCCGACCGAGGGGGGATCGACCTTGGCCATGCCCTGCACCGGGAGTGGAGTCTCCTCCAGGCGTTCCCATCCGACGACATCGAAGCCTCCATAGATATCCACCCCGGAGGGCAGCGTGATGGACTCCTCAAAGCCATCGTTCGTGACGAACACGCGACCGCGCCCGGTGCGCGTAAGCTCGATGCCGCGCTGGATGGAACGAACCGGCCTGTCCTTTGTGCCGGGGTTCGCGTCGTCACCGCCGAAAAATGGATGGTTGACGAACACGCCGCAGCCGTTGATCACCTGACCCCTCGCAAGCTGCTCCAGGCAGACGGACTCGGGGATCGGATCGTCTGCGCACGTCGATGGATCGTCGCACGGCGGCGCACCGTTCGGGTCGTCTACCCCCGGTGCGGTTCCGCAGCCGGCCGACGCGAGCGGCAGAGCAAAGACGAGGAGGATCGTATGATTTAGGTTCATGGGCATCCCTCGAGGGCAGCGTGTCGCGAGGCGCGATTCAATGGATCGGCTCGCTTGCCGCAGGGAAGGCATACAGAGCAGCTTGTGGGCCGGTTTTCCCTTTACCCACCTCGTCCTCCGGTCCGGCGTTCCCCGCGGGGCCGCCTGCACCGGCGTCTCCGGGAACAATCGTGGTCCCAGGCCTGATGGCGAAGTTAGGCACCACGTAGGCGATGCCAACGGACGCGCCTCCGAGCCCGCCGCCGGCATCACCGCCGCGGCCGCCGTTGCCCCCGTCGCCGCCCTTGCACGCATCCCACATGCCATCCACAAGAGTTATACCGCCTGGAGCGCCATGATGACCTGCGCCCCCCGGCTGGCCCGTCCCGCCCACCCCACCCTGGCCGCCTTTGCCCGTGAACACGTCCGTATCCGTGACGGTTAGGTCAGTGCCCTCCAGCGCGACGATACCAATGCTCGCGCCGCCATAGCCGCCGCCCCTGCCTCCCTTGCCGCCGCAACCCCCGCTTCCCCCCGAGCCGCCGGCCGCACCACTTTGTAGGCCGCTTGTCGGACACGCAAACATCGGCCCGCGCGACTTGCTGCCGCCGCCGCCACCACCGCCCTGGCCGACGCCGCCCTTCTTCCCGTCCTCACCACGGACACCGATCCATCCATCCTCGCTGAGGAAGCCTGGACCAAACGCGCCATCCGCGCGACCACCATCAGCGCCGTCTGCGCCATCGCCTCCGTCCTCGCATCGCGTGCGGTCCGCGCCGAGCCCCGCGTGGCCGTCGCGCTCCGAATTTCCCCCGAGCGCCGGCTGTCCCGGTGCGCCATCGCCGCCGACGTCGAGCCCGCCGTCACCGCCGTAGCCGCCCGTCGACTCGATGCCGTCGCCGCACACAGTGACCACCGGAAGGGCGCCCACGGTGGCGTCCGCGGTACATGCGTTCGCGCCGTTGATACCTACGACGCCAGCCATCGCCCGGACGCTGAACGCGTCCCCGCCCGGCTCCCCGTCCTTGCCGTCGCCCGCGATGATCTTGCTGTCCGACACGATCGCCCTGGCCCCGGCGCTCAAAATCATCGCGATCGACGACTTGTCATCGGGCGTCGAGGCGTTCGCCGCGACAATTTGCACGCCGGCGATCACCGATGTCGCGTTGTCTCCCGCGAGCGCCGTACCCTCCGCCCCGAGGACCCGCAGCGGGATCCCCCCTGGCGGAGCGATGATCGTCGGGTGATCCGGCCCGCCGAATGATCCCTGATACGACCAGTCCCCGTCGTCACACCGACGCCCGCCCCAGAGGTCGACCCCCGAGGGCAGGGTGATCTCCTCCTCGAGCAAGCCGCCGCACGCAAACACGCGCCCGGTCCGCTTCTCGCCGTCGCCTCGTCCGTGTGCCGCGAGCCCGATCGCGTGTTGCAGGGTCTTCACCGGCGCGTCCTTCGTGCCAGGGCTGCTGTCGTCACCCGACAACGGGCTGACGAACACCCCGCACATGTCGAGCGCCGGAGCCGCAGCGGGGTGTCCCTCGCACGGGTCGGGCGGAGGCTCCGGATCGGGAGGACACTCCAGCCTTTCCCAGCAATCGTCGGAGTAGGAGCTGCATGATGTCAGCATGCTGGCTCCCCACACGCAGACTGCGACAGCAGCGACCGACTTAACCGCACATCGGCGCGACAGCGACCCCATGCCCTTGGCCTCCTGCACGTTCACCACAGCGCCTCGATTTGCGCACCGATTTCGTTCCTCGTGGCCACGGGCGAGACATGGATGCGATCCCGAGCCGGCGAGAATCCTAGGAAGGAGAAGTCCGTGAAGAAGGACGCGGCGGTCACCGCGCCGACGACCCCGCCCGCGATGACCGTGGCTACCCCCGCGCGGCCGGACAGGTTGCGCGCGTCTTGCAGGCGCGCCAGTTCGGCACAGGGCGAGTTCAGCGGAGCCTTCCAGCACGTCGACGAGCTCGAAGACGGCTCGCCCAGAAGCCGGTTACGCCGGGCGGTCAGGTCGTCGTCGAGCCTGCCCGCACGAATCATGAGGATGGTGCCGATCGACATGCCGGCCGTCGCGGCGGCGATCCCTGTGACGCGCAGCGTCCCCGGCCAGGAAGCCCACGGGTCGGGCTCTTTCGCGCGTGCCGTGGGCATAGCGCGCGCGGTCTTCGGCACCGCCGGGGCCTCCTTGGCGCGGCTGACCGCCGGGCCCGGAAGCTTCATCGAGATCTCCTGCTTATCACCCGGCTCGCCGTTGAACGCGTGAAAGCCATCCTCGCGACCCGGCGCCCGGGCCCGCACCATGTGTCGTCCGGGCTCGAGGAACAGCTCGTAGGTCCGCGCGGTCCGACCGATCTTCTGGCCGTCGATAAGGATCTCGGCGTCAGGCGGGTCAACGGAGAGCACGAGCTCAACGACGTAAAACGCGGCCTTCCGCTGGCCGGTCAGGAATCGTTCCTGAAGCTGACTCGGCAGCGCCCAATCCCGCTCAAGACTCCAGGGCAGGTGCTCCGCCGCGTCACGGTACTTACGCAGCTCGAGCTCGCAGAGGCCGAGTTCGCCGGCGATCTCGGCGGGATCGAACGCCCCGCGGTCGACTTCCGCGCGGTCGAGCTTCATGCCGGGCGGCACGTTTGCGGCATCAAGGGCCGCCTTGTAGGCTTCGTAGGCCTGCGTCCGGCTTCCGCGGTCGCGCGCTTTCCGAGCACGGCGAACAAGGTCCTTCACCGTCAACCCGTCGCTTCTCCCCGAGGCCGGAGACCGCTGTTGAGCATCGGCCGAGCTGACCAAGCCCGTTGAAGCGCCAAGCGTAAGCAAAATGAACAACAGGTGCGCACCGCAACGCATGCAACGACGGTGCTTACGCCACGCGCGCGACGTCAACCGGGAAAGAATGCTGGGAAGCAGCGCTTTAGACGAGAATTTTCAGGAGGATGGCGGAATCAAGTCATCCGTCCCGTGTGTCGGCGATCTTCGAGCCGACCCAGATAAAATGTAGCGCCTTGTACTACATTGTCCTGCCAAAGTGATCGCGGCCGTGCATTTTGCTGACCCCGAGGGGGTCGCTCAGACGTGCTACCAGCGTGGGCAACCCGTCGAGCATCTCGAGCAGCTTCGAGCTCTTCCGGCGCCTCGCGAGGCGTCGCGGCGTTCCGGCACGCGACGCCGAGGACGTGGCGCAAGACGCGCTCCTGCGCGGGCTGGAAGCGGACCAGCGGATCGCTCCGGGCGGAGACGCGGCGGCGTACCGCGTCACGATCGCCATCAACCAGGCGCGCGACCATATTCGGACCGCGCGCCGTCGCGGAGAGGTCCTGACATCGTTCGACGAGAGCGAGCTCCGAGCCCAGTGCCCGAATCCAGAGGAGCTGGTACGCGGGAGCCAGCGGAACGCGCTCGCGCGCCGCCTGATCAACCGGGTCGACCCGAAATACCGGCACCTCCTGATCAAGCATGACCTCGAGGAGGTCCCGCTCGCCACGATCGCCGGCGAGCTCGGCCTCACGACGGAGGCGGTGAAGACGCAGCACCGGCGGGCGCTCGAGCAGCTCGCCGAGGAGAAGCGCCGCTATACGGCCGAGCAGCATGCACGGGGACGGGACGCAGAGGCGTGCGTCCCGGTGGCGCTCGGCCTCTACCGTCGCGAGTCGTGGCTGGCCACGCTGCGGCGCCTGGTCTTCAGGATCCTGGCACAGGGCGCTCTCGTCGTCGTGACGGGCGCGCTGATCTCCGGGCTGTCGCACAGCCTGGAACCCTGGCTGTTGCCCGCGGCGGCTCGCGCGCCCGGCTCCGCGCCCGCCGCGCAGGAGGTCACCGCGTCTGCCCGAGAGGGCGGCTCGAGCGCCGCCGCCGAGATCAGTGCGCCGGCCGCGCGCAAGGTGGAGCCGTCCGCGCAGCAAGGCGACGCTAACGCGCTGGCCGCCGTGGATAGGCCCGCTGCGTCGGCCGAGGCTCCCCCCCCGTAGCGAGGTGCCCGGGAGTGTCGTGCGCCGAAGCACGGCGCCCAGGAGCGCCGTGCGCCGCGCCGTCAGCGAGCGCGAGCGGCGGCTGATCCGCGACGCTCGCCGCGCGCTGGACGCCCACACCGCCCTCGACGACCTGGAGGCGCGCCAGCTGCTCGAGATGCACAAGCAGGAGTTCCCGCAAGGGTGGCTCGCCTTGGAGCGCGAAGCGCTGCTCAAGCAGATTCGCTGATTCATCGGCTGTCGCTCGACAGCTATAGGGCGTCCAGGCTTTCTAGGGCAAAGCAGTCCTGCCCGCCCTCCTGCGCAGTCCTGCCCGCCCTCCTGCGCAATCCTGCCCGCCCTCCTGCGCAGCCCCGCCGCGGCCGAGACGCCCGGGCCCGCGACGATCACGACGTTGCCGTTCCGGCAGGTGACCTCGAGATCTCGAGCCTCGGATCGCGCGCCATGCGCGCATTTCAGGCGAGGTCACGCCGAATGCGGCGTGCGGCGTCGAGCGCGCCTTCGAGGTAGCCGGCCGCATAGCTGGCCGTCTCGGCGGCGCCGAAGAACACCTGCCCGCGAGCGTACGGCTGCCGCAACAGGGGGTGCCCTGACCCGATGTGCTCGGGGCGCTCCTCGCGGTCGCGGGCGCTACAGGTGAACCGGTCGGTCGCCCAGTCCTTGTAATGCTGCTCCACACGCGACAGATGCTCGCCGAACACCTGCGCGATCTGCTTGTCGATGAGGAGGGGGAGCTCGGCCGCAAACCGCGCGCGCGCTCCGGCCGGGAGGGCCAGAAACGCGCCCAGCGCGCTGAGCCCATGGAGCGGATCCGACGCGTCGAAGATCTCGCCGAACACCGCCTGACCGTGGGTCACGAAGGCGTTGCCGGACAACCCGTCTTCGCGCCAGCTCGGCTGCCGGTAGGTGAGCACCGCCTTGGCTTGCGCCGCCATCCAGGTGGGCGTCGCCGTCATGGCTTGCCGCAGCGGCGCCGGCAGCTCCGGCGTGAACCGGACGTTCTCGGCGAGCAGGCGCGGAGGGAGCGCGAGCACGACGCGACGGGCTTCCACCGTGAGCCCGCCGTCGCCGCGCGCAAAGCGGAGCAGCACCTTGGCGTCGTCGAGCTCGACCGCCTCGAGCACGTGACCGAGATGCACGCGCTCTCGCGGCACCGCCCCCGCAAGGGCATCGACCAGGCTGCCCATTCCTCCCACGAGCCTTAGCCCGCCCCCGTGCAGGCCCGTGTCGCCCCTGTAACGCTCTGGTGTCTTGTTGGGATGCGACAAGACCATGATCGGTCCGTCGTCGTGCTGCGCGAAGGACGCGAGTTCGAGCTCGTCGACGAGGCGGCTCATGAGCGGCTGGGTGACGGGCCAGAACCAGGTGGGCCCCAGGTCCACCCGCGTTGGGCCGGCAGGAACAGAGAGCACGCGACCCCCGAGCCGATCCCGAGCCTCGAAGAGCTGGTAGTCCGCACCCACCGCGGACAGGCTCCGCGACAACGACAGGCCGCACACTCCACCACCGATGATCGCCGTGTCGAGCATAGCATCTGACCTTTACACGATTCTACAAATCCGTTCAACAGGCCGCGGGGGCGTCGTCCAGCGCAGGGCGGGTGCATCCGCAGCGGATCCTGGGGCCGGTCGAGCGAATGCGGGCCCTCGGCCGGGGGCGAGGGCGTGCGTGAGGCCGGCGTCCGGCAGCGCAGCGCAGCCCCTCCAGGGGACCTGGTGCCGGCGCAGCGGCGCCCCGATTGAGGACGACGCACGGCCTGCCGGGCGACGTCACGTCCAGGCGGGCGCATCGAATGGGTACGTGTCGTTGGAGCGCGACACGTCGTCGTGCCTGCACAACGCAGGGATGTCTCCCGTTCCGTGCCGCAGCGCGACCGCGCTCTGCTGCTCCGGCTCGGCCTCGACTTGGACAACCCCGCCCACGCGGAGCTCTTCGTCGAGGGCGTACGTGCCGCGGACGATGACATCGCGGACCAGGTGCGGTGGGAGCGGGAGCGGGAGCGGCTGGGCTGAGGGCCGCCCGTGTCGTTGGACCAAGCCGCTTCGCGGCGGCTCCAGACTCCAGGAGACCCTGGGAGCCATGGACCTGGCGGCGGCGCTCGAGGCCGCGAGCGAGCGCGATGCTGACGAGGTGCAGGCGCTCGGCGTGATGCTCAAGAAGATGCTGCGGGTCCTGCTCCGTTAAGCGTTCCGGTCACCGAGTCGCCAATTCCTGCCGCCGCTCGGGTCCTTGTCTTCGCTGCGGTTGTCACGGCAGTGATCGCTGCCGCCGCGCGGCTTTTGCCGGTATTCACTGCGAAAAAAAGCGCCCGGCTCAGCGTAGAATGCGTATTCCGACGGACGTGACGGCTCGTTCCGGAGCGACGCGACGGCCCAGTCCGGCGTGACGTGGACCGGAGCGCAGTCAGGTCTTCGTCTCGGTCACCTCCGGAGCCACCGCCTTCTTCTGCCGCATCGACCCGCCGCGGAGCGTCACCAGGCGCGCGTTGTGGACGACGCGGTTGCAGATCGCGTCGGCGATACTCGCCTCTCCGATGGCTTGATGCCAACTCTTCGTCGGGATCTGCGAAGTGGTCACCGTTGACGACCTGTCATATCTATCCTCGAGGACCTCGAGCAGGTCGCGCCTCTCGACGTCGGTCATGGGCGCGAGCAGGAAGTCGTCGAGGACCAGCACGGCGACCTTGGCGAGGCCCGCGAGGGCGTTCGCGTAGGTCCCGTCGGCACGCGCGACCGCGAGCTGCTGGAGCGCCCCCCGGGGCGGCGGCTCGACCAGCGGCGCGCGGTCGAGGCCGTTCCTCAGGATCGCGGTCACGCTCTTGGCGGTGGGGCTGCCGATGCGGAGCGCACGCGCGCACGCAGCGTCGACGCGCTCGCGACCGTACTTGTCCGCGAGCCGGATCACGCCCAGGCACGTCCGGTAGCCCGTCTCCGGGTGGGTGCGGTGGCGCATGACCGCACGCGCGAGCTCGCCGACGTTCGGGCCGATCGTCTCGGCCCATGCCACCACGCGCTCCGGCGGCCACTTGCCGTAGTCGCGATGGGCTCTGGGGCGATGCTCGTCGACGATCACGGCCGACCCCTTCCGGCCGTAGCTGCGCGCGTGCGACGCGACGCGCACGCTGTCATGGAACAGCTCCACGACCGAGGCCGTCGCTCGAATCTCGACGCGCGCACCGACCAGCGTGTACGGCACGCTGTAGAGCCGGTCGTCGTAGCAGACGCAGTAGTCGATGTTGACCTTGGCGTGCTTCCAGTCGGCGAGCTCGTACCGCCGCGCCGGCAGCGGCCGCATCACGGGCTTGTCGATGGTCTCGAACGCCGTGCGCCGGCAGCTGACCGATCGCCTCGTGCACGACCCGGGCTGCCTCCTCATCGCCGAGGGCGACGGCACGGCTTAGGGGGCCGGCGAGCGACGCAACCACGGCGGCCCGAGGCGACGGCTCGACCATCGCGAGCTCTCCGGACCCGAGTCCCCTCGGTTGGGCCAGGGTTGGGGCCATGCCGTCCGAGGGTCTGCGATCGGTCGTCGCTCCCCCCCGAAACCCCGCAAGAAGTGACGGATCGCGACCGTTCGCCACCGCGGCGGAATCCTGGCGGGATCTCCGACGCGCCGCCCTAGCCTGGTGCAGCGCTGGCCGAGCCGCCGATCGCCTCGGCCGTGAGCAGCCGCGTCCGCCGGCCCGAAGCGAGCGTGAGGTGCTGCCCCCAGCTCGTCTGGTGCGGGACCTCCCCGTCCACGATCTCGCTCGTCCGGATCTCGAACCCCGCGGCGCGGTAGGCGGGGCGCAGCGCGTCGTCGAGCCACGCGTCCGAGAGCTCGGGGAGGCCGAGCCGCGCCGCGTAGGGCCGGTCGTCGAAGACGCTCTGGTTGAGCAGCGCGATGAGCTCCCCGCCCGGCCGGACGAGCCGGCGCAGCGCCTCGAGCACGGGCGCCTCGGGGAGCACCAGGGCCGAGAGCAGCGACGCCCAGGGGAAGTTCAGCGTCAGGGTGTGGGCGAGCCCGGCGAGCTCCTCGGGCAGCGCCTGCACCGACGCGACCACGAAGAGCGCGTTCGGCCGGCCGCCGCGGGCGGGCTTGCGGCTGGCGCGCCACGACACCTCGCGCATCCGCTCGCCCGCGGGGTCCACGCCGATGCAGTACGTGTCCGGGTGGGCGCCGGCCGAGCGGTACACGAAGCGCCCGTCGCCCGTGCCGACGTCGATGAGCACGCGCGCGTGACCGGCGAGCTTCGCCTCGAGGTCCGCGCGCGTCCACGTGACGGACGCCTTGCCGAGCTGCACGATCATCGCCGCCTCGAGGACGCCGTCCCGGCCGCCCGCTCAGCGCGGGGCGCCGCCGCTCCCCGCGCGGGCGCTCTGGGGCGCGCTCGCCGCCGCGAGCTCCCGGCAGCCGATCGCCCGCGCGAGGTCGTCGATGGACTCGCGCAGCATCCGCACCAGCATCGGCAGCCGCGGCGCCGCGCCGTCCGGGGCCCGCTGGAGCGCCGCGAGCCGCGCCTCGGCGGCGGCGAGGAGGTCCCGATCGACGCGGTACGACGGGAACAGGTGGGTGAAATACGCGGACGCGAGCTCGTGCGTCCGCGTCTCGAAGACCTGCTGCACCCGCTCGAAGAACCCCTGCACGTACGGCTCGAGCAGCGCGCGCTGGAACGACCAGTTGAAGCCCGACATGGCCGCGCTCGTCAGGTGCAGCGAGCCGTACCCGCCCTCGTGGAAGCGCTCCCACGCCGCGGCCTTCGCCGCCGGATCCGGGCGCGCCGTCTCGGCGCGCAGCGCCGCGCGCTGGCCGCGATCGGACGGGTCGCGCTCGCGCTCGGCCGCGAGCCGCGCGTCCGCGCCGGCCATGCCGCGCGCGATCCACTTCACGGCCACCGTCCAGCGCATCTCCTGGTCGATCTCGAGCCCCTCCACCGCGATCTCGCCGTCCACGAGGCGCGCGGCCAGGGCGAGATCCGGCGCGGCGTAGGCCGCGTTGAGGAGCGCCCGCGCCCACACGATCTGCGCGTCGCCGCGGGGGGCCGCCCGGAGCGCCGCGAGGGCGAGGGCGGTGAACGCGCTCGCCTCGACCTCGCGCATCGGGTCGGGCACGTAGCGCGCGAGGGCCGTCACCGCGTTCGAGAGCACGGGCTCGACGAGCGAGAGGTCGGGCTCGACGGGCAGCTTGTCCCTCACCAGCGCGAGGTACGCGGGGGAGGCGAGCTTCTGGTCGCGCACCATGCTCCAGAGCGACGACCAGAGCAGCTGGCGCAGCAGCGGATCCTCGACGCGGCCCATGTGCTCGCGCACGAACGCGAGCGAGCCCGGGTCGAGCGCGATCTTGGCGAACGTGAGGTCGTTGTGGTTCGGGAACACGAAGAGCGGCGCGCGCTGCCCCCGCGCCGCGGCGACCTCGGTGGCCGCGCCGTCGATCTCGGCGGGCACCGCGTCGACGACGAGCGCGCCGCCCTCCTCGCGCGCGAGCGCCACGTCGATGCGGTGCGGCCGGAGGGTCGGATAGTCCTCGGGGGCCGTCTGCAGCACGCGGAGCCGGCCGATGCGGTCGCCGTCGGGCTCCCACTCGGCGGTCAGCGTGTTGAGCGACGCCTGCTCCAGCCAGACGCGCGACCAGGCGCCGAGGTCGCGGGCGGAGCCCTCCTCGAGCGCGGACAGGAACTCGCGCAGGGTCGCGTTGCCGTACTGGTAGCGCTTGAAGTACCGGCGCATCCCGTCGCGGAAGGCGGGCAGGCCGATCGCCGCGACGAGCTGCTTCATCGCGGCCGCGCCCTTGCCGTAGGTGATGCCGTCGAAGTTCAGGAAGGTGTGCTCGGTGTCGGCGAGCTCCCCGGCGATGGGGTGCGTCGTCACGAGCTGGTCTTGCCGGTAGGCCCAGCTCTTCATGACGTTGAACGCCTTCCACACGGCCGGCTGGAACCGGGTCGCCTGCTCCATGGCGAGGAAGGCCATGTACGTGGCGAAGCTCTCGTTGAGCCAGAGATCGTTCCACCACCGCATGGTCACGAGGTTGCCGAACCACATGTGGGCCATCTCGTGGAGGAAGACCTCCGCGCGCGTGAGGCGCTGGTGGTCGGTCGGCGGGTCGCGGAAGATCATCCGCTCGCTGTGGGTCACGGCGCCGGCGTTCTCCATGGCGCCGGCGTTGAACTCCGGGACGAAGACCTGGTCGTACTTGGTGAAGGGGTACGGGTAGTCGAAGAACTCGGGGTAGAAGTCGAAGCCCTGCTTGGTGATCGTGAAGAGCTCGTCCGGGTCGAGGTGCTTCTCGAGCGATCTGCGGCAGTAGAGCCCGAGCGGGATGCCGCGGTGCTCGTCGCGGACGCCGCTGTAGGGGCCGGCGATCAGCGCGAAGATGTAGGTGCTGAACCGGGTCGTCTCCTCGAACACGCGCGTCGAGCGCCCGAGGCCGGCGCCGATGGTGCGGCGGATGCGGGCGTTGCCGATGACCTCCCAGTCCTCGGGCGCGGTGACGGAGAGCCGGTAGCTCGCCTTGATGTCCGGCTGGTCGAAGCAGGGGAACAGGCGGTGGGCGCTGAACGGCTCGAGGTCCGAGTAGAGGTAGTCCTCGCCGTCCTCCGGGTCGCGGAAGTGGTGGAAGCCGTCGCCGGTGTGGTCGTAGTCGTTCTCGTAGACGACGCGCACGCGCGTCTCCGGGTCGAGCAGCTTCCCCGGGAGGCGGATGCGGCAGTCGGACCACTCGGGCTCGACGGGGACGCCGTTGATCTCGAGCCGCTCGATGCGCCGGCCGCGGAAGTCGATGAAGGTGTCGCCGCTGCCGCGGACGTCGAAGTAGGCGATCGCCTCGCCGCGGTAGCCGCCGTCGCCGCGCGACAGGTCGAGGGAGAGCTCGTAGCGCGCGTTGCCGATGCGCGCGGCGCGCTCCTCGGCCTCCTTCTGGGTGAGCACGTCCCGTCCAGGGCCGCCGGTCTTTTCCGTCATGACGTGCACACCCTAGGACGAACCCCCGGAGGGTGGCCAGCGATCTGGCGCGGTCGCGCGCGCCGCCCTGCCGCGAGGGGCGGGAGGGAGGCCGCCGCCGGGCGGCCGGTGGAGGGGCGAGGGGGCGGACGGCGGGGCGAGGGAGCCGAGGGAGCCGTCCCAGGTTGGGGAGCCAGCCAGCCGACCCAGGTTGGGGAGCCGTCCCGGGTTGGGGAGCAGCCGACCCAGGTTGGGGGAGCCGACCCAGGTTGGGGTACCGACCCAGGTTGGGGTACCGACGCCGCGGGCGGCCTCCGGACGGAGCAGCGCGCTCTGGGTCTGTGCCAGAACGGCGTTGTTCTGTGCCAGGGGAGGGGGGTCCGGCACCGGCACAAACGCAATGCATTGCGACACACCGGGGTCCGGACCCCTCGAGAACGCTCGGCGGAGCAGTTTTTAGTGCAAGATTGTGTCAGAAAACGCGTTCTTCGAGGAACTTCTGCGCCAACGACCCCGCGTCCCCCCTCCTTTCTGTGCCAGAAGGGGGGTCCGGACCCCTTCGGACCGCAATGCAGAGCGCTGGCGGGGGTGCCCGACCCCTCCCGGGACGCAGTGCAGAGCACGCGCGGAGGTGCCGGACTCCCTCCGGGGGCAAGGCCGCGCGAGTGGGGGAGCGCGACGCTTGCTCGGCGCGGACCTGGAACGCCCCGTCGGGCCGAGCCCGAGCGCCTACCAGGCGGGGCGCGTGCCGTGGTGGCGCGTGCGCGGGCTCGCTATGATTCGGACCATGCAGCGCGCGCCGACGTCCTGGGAGATCGACCCCGACGATCCTCGGGCTCCTCCGCAGGAGCTCTGGGATCGCATGACGCCGGAGGAGCGGCAGCGCGTCCTCGACACGCTCCCGTCGGAGTTCGAGGTCTCGGAGGCGAGCCCTCCCGAAGGCGACTTCCACTTCAATCCGAAGGTGGCGGCCCGGGACACGCTGGGCGGGTATTTCCAGCGCATCGGGCGGCGCGTGTACCTCGCGTGCGAGCTGCCGGTCTATTACCCGGCAGAGCGGATGTTCGCGCCGGATCTCATCGCCGTGCTCGACGTGGAGGTGCAGGAGCGGGCCCACTGGTCCGTGAGCGCCGAGGGCAAGGGCGTCGACCTGGCGCTGGAGATCCTCTGGAGCGGGAGGAGCAAGAAGGATCTCGCGGACAACGTCGCCCGCTACGCGTCGCTGGGCATCTCCGAGTACTTCGTCTTCGACCGGCGCCGTCGCCAGCTCCGCGGCTTCCGGCTCGTCCAGAGCAGCGGGCGCTACCAGCCGATCGTCCCGCAGGAGGGGCGGCTCACGAGCGCGGTGCTCGCCCTGGACCTCGGCCTGGACGGCGATCGGCTGCGCTTCTTTCACGGGCAAGATGCGCTGCCGGAGACGCGCGAGCTGCTCGACAGGCTCGGCACGATGGTGGGCGACCTCGAGGCGCGCATCGAGCGGACCGAGCTGCGCCTCGATGAGGAGAGACGGCGGCTCGACGAGGAGCGGCAGCGCGCCGACGAGGCGCAGCAGCAGCTCAACGAGGAGCGCCAGCGCGCCGACGAAGCCGAGCGCAGGCTGGCCGAGGCCCTCGCCGAGCTCACGCGCCTCAAGGGCGAGCGCCGCTGAGCGCCCCGCCCGCGGCGCGCGACCTCCCTGGCCCCACCCGAGCTCGGCTCACCGCCGCGGCGGGCTGCGCCGCCACGCCAGCGCGGCGGCGATCCCCGCGAGCGCGAACGCCGCCTGGAGCAGGTGCACGAGCAGCGAGACCGCGATGGCGGAGCTCGCGGTGAGCCCGAGCAGCGGGGCGGCGAGCGTGAAGGCGCCGTCGGTGGCGCCGATCTGACCCGGGATGAGGTCGCCGGCCGCCGTGCCCGCCGCGCCCACGCCGTACGCGGCGAGCGCGCGCAGGAGGCCGCTCTCGGCGCCGACGGCGGCGAGGAGCACGGCGTACTGCGCCGCCTGGAGCGCGCGGCCCGCGACGCAGGCGGCGAACGGCCACGCCGGGACGGGTGGGCGCTCGCGGACCGCCTCCTGGAAGGCGACGGTGAGCTGGCCCGCGCGGGCGAACCGCCGGGTGAGCCACGCCGAGGCGGCGCGCTGCCGCGCCGCGAAGGCGACGCCGAGGCCGCTCGCGACGAGGAGCGCGGCGTGCGCGAGCACGCCGAGGGCGAACGGGGAGGCGCCGCCGCCGATCCGGAAGAGCGCCGCGGCCGCGAGGAGCGACAGCGGCGCCGCGCAGAGGAGCGCGAGCGACTGGTTCGCCGCGGCGATCGCCGCCGCGCGCGGGGCGCCGACGTAGGGGGAGAGCAGCGCGGCCTTGACCGCCTCGCCCGCGGCCCTGCCGGCCGGCATCAGCGCCATGACGGGGTAGGAGACCGCGTGGATGCGAAGGAGCTCGGCGGTCGGGACGCGCCGCGGGGCGCAGAGCAGGCCGGTCGCGAGCGCCTCGCAGCCGACGCGCGCCGCCTCCAGGGCGACCAGGAACGGCAAGAACGGCGCGGCGCGGATCACCGCGTCGAGCATCTCCGCCGCGCCGACGTGGCGGATGAGCGCGGCCAGGGCGGCCAGGCCGAAGGCCGCGAGCGCCGCGTGGAGCAGCGCCTTCCACCGCGCGCGGCGGGCGGCGGGCCCGTTCAGGGCGGCGGGCGGAGCGGCCGGGACGAGCGCCCCGCCGACCGGCGCGGGCCCGGGATCGCCGCCGGAGCATTCCTCTGCCGCTCGGGCCGGAGGCAAGGGAGCCATGGGGAAGAGGGCTGCGAGGCGTATGCCGGCGCCGTGTGGGCGCGGCGTGCGCACGCGGCGGTGAGCTGCCTCGCGGAGCAGGCACCCTGGGCAGGCAGCGCGCGCGCGGTCGTGACGCGGTGGTGAGCTGCCTCGCGGAGCGCAGGCGCCCCGAGCGAGCAGCGCGCGCACGCGGCGGGCCCGCGTGCGCGCGACCGCTCACGCAGGCGCGAGCGGGGCGTGGAGGCGCGCGCCCGGCACCACGATGCCCCCGCGGTCGCCGGGGGTGAGCGAGCCGAAGCGCTCGCGGAACACCGGCGGCAGCGGCCGCGCCCCGGGCGGAGCGAGCCACAGGCGCAGCAGGTGCCGCTTGCGATCCGGCTCCGGCCAGTCCTCGAACGCCGTGCGGTCGTGCAGCAGCGTGTGGTTGTGCACCAGCTGGATGTCGCCCGGGCGGAGCTCCATGGTCATGTGGAGCGCAGGGTCGTCGGCGAGCGCGTCGAACAGGTCGAGCGCCTCGACCTGACGCGCCGTGAGCGGCGGGACATCGGGAAAGCGGCGCGCCGACTCGATGTACTGTCGCTGGTAGATCGCGGACAGGAGCCCAGCGTGCCAGTTGAGCACGGGGATGCGGAAATACGGCCTCTCGCCCGCCGGCACCTCGCCGCGGCGATCGGTCTCGATCGGCGCGAACAGCGCCTCCGCGAGGTCCGGGCGCGCGCGCCGCATCTCGTTGTACAGCGTGACCGAGCTGACCAGCGCCGAGAGCCCGCCCGCCCGCGCGGTCCGCAGGCAGAGCAGCGCGACGACGTCGCACGAGTCGGTGTGGAACGTCTGCCGCTCGCGCGTCTGGTAGATGCGCACGCTCGGGTCCTGGCTCGACAGGCCGAGGTCCTTGACGTGACCGAGGACGTGCCCGCGCGCGTTCTGCGAGCGCGCGCTCCCGAGGTGGCTGCCGATGCCGAGGAACGCGATCGCGGCCGCGCGCAGGTCGTCGCGGCCGCCGCGGTCGAGCCAGCGGCCGCGCAGCCCGCGGAGCAGGGCGAAGCCGCGGCCGTCGAGCACCTCGGCGAGGACGCGGCGGAGGCGCGCGGCGAGCGTCGGCAGCGGGAAGCCCTCGGCGCGGATCTGCGCCGGATCGGCGCCCGTCTCGCCGAAGCGGCGGACGGCGGCCTCGACCTCCTCGACCTCCGCGGGCGTGAGGTGCTCGATCCAGCCGTCGCCCCGCGCCATCGCGGGGCCGTACCAGGCCGCGGGGCCGGCGATGTGCGCCGGGATCCGAGAGAGGTCGGCGATCGGTAGGGGCTCTTCGGTGCTCATGGGTCGCTACATGCCGAGCGAGGTGCGCGCGGCGGTGGAGGCCCGCGCGCGCAGCGCGGCGTCGGCGCTGAACACGGCGAGCCCGGTCCAGATGCAGGCGAAGCTCACGGCCTGGGTGGCCGTGAACGGCTCGCCGTAGACCAGCACGGCCAGCAGGAACTGGCCGCTGGGCGCGAGGTACTGGAGGAAGCCGAGCGTGGTGAGCGACAGGCGGCGCGCCGCGTTCGTGAACCAGACGAGCGGCAGCGCGGTGATGACGCCGGTGGCGGCGAGGAGGAGGTCGGTGCGGAGATCCACGCGGCCCATGGCGCCGGCGCCCTGGGCGTGGAGGGTGGCCAGGTAAGCCGCGCCGAGCGGGGCGACGAACAGGGTCTCCAGGGTGGAGCCCGGGAGCGCGTTGACGGCGACGACCTTCCGCAGCAGGCCGTAGACACCGAACGTCCCGGCCAGGGCGAGCGCGATCCAGGGCACCGCGCCGGCGCGCACGGCGAGGTGCACGACGCCCGCGGCGGCGAGGCCGAGCGCGAGCCACTGCGCCGGGCGCAGCCGCTCGCGCAGGAAGACCATGCCGAGCAGCACGCTGAGCAGCGGGTTGATGAAGTAGCCGAGGCTCGCGTCGAGCACGCGCCCCACGGCGACGGCGTAGATGAACAGCACCCAGTTCGCCGAGACGAGCGCCCCGGTCGCCGCCATGGCCCCGACGACGCGCCGGTCGCGCAGCGCCGCGCCGAGCGCGCGGAGCTGCCCCGTGGCCAGCGTGAGGACCGCGAACGCGAGCAGGCTCCACACGGTGCGGTGGGCCAGGATCTCGACCGCGCCGACGTGGCGGAGCTGCTTCCAGAAGACGGGGACGACGCCCCAGGCGCTGTAGGCCGCGACGCCGTAGGCGACGCCGAGGGCGGCCTCTCGGCGGCTGTCGCGGGGGTCTTCGGGCGTGGCCATCGGCGATCGCGTCTGCGGAGTGCGGGCTCAGGGCGCGACGCGATGGGCAGCGGGGGACGGCTCGCGTTCGACCACAGCGGCAACATGGCGAAGCTGCCCCCACGTTTCAAGCAGCTTCTGCGAGCCGATTCACCTCTCGCCGTGAGGCCTGACGTCCTGAGAGGGGCGCCCGACGCCGTTCGCCGTCGCGTCGGCTGGCTTGCCGCCGCGCTCGGGGGGCGGGGTCATCCCGATCATTCCTGATCGAGCAACCCTTGGCGCAGGTCCTTGAGCGTCTCCTCGAGGCGCTTGACCTCGTCCTTCGACAGGCTGGAGCCGACATGCACCGGATCGAACACTGCCACGCCGTGACTCTCCGGGGCGCCGCCTGATATGCCCAGCTTCTTGAACATCACGTCGAGCGGCGAGGGATCCTTCTCTTTTTTCTTCTCGAGATTCCACTCGATTTTGATCTTGCTCACACGGTGCTTCGCTGGACCGTGCTGGCCCTCGACCGAAAATGTCACCTTCAGCGGCTCGTAGATGCCCTTGTCAGCTGCCAGCCTGGCGAGGGTCGCGACGTGTGACTCGAAGGGTATCATGTGTGTATTCGCATCCCTGGTGCCCACGACGAGGTTCGTGCTGTCCGTGACGCCGCCCAGGGACGCAGCGCGGACGTGGAGCCACTCCCATCGGGAGCTCTTCCATCCGCTGATGCCCGCCAGCCAGGCGTAACCCGTGGCGTTGGTGTTGCCCATGGCTTTTGCTTGCGTCTCATCTCGTTCCTTCCGGCGGGGCGAGCCGGAGTACTGCGTCTCCTGCGGGCTCTTCACACGCGCGAGGCCTTCCTCCAGGCTCTTGAGCTCGCCCTCGGGTGGGGGCTGCTCGCTGTCCATCGGCTTGCCCCTGACAGTGACGCTTTTGCCGGCGGCAGCATCGCTCGCGCGCTCCTCCCCTGTCTTCTTGAAGACCTTGAACCGCTCGCTGAGCAGGGTACCGCCCAGCGTGGTGCCACGGGTGAAGTCAGTATTCTCGGTGTAACCTTCGGGCGCTGGCTCGCTCCGGTCCTGGATCTTTACGTCTAACTCGGATGCTCGCCCCAGCGCGCTGAAGCCGCCTTCTGTGGTTGAAAATGTTCGTTTGATGTTGCTGAGCAATTGGTTCAGTTTGCGTGTGATTCCGTTCAGCTGCTTGGCGAGCGGCACGCGCGACTTCCTGTTGTTCGCTTCTTCGTACGCTGTTTCCAGCTCTCGGCTTTCCTCTCTCAGCTTGTTTGCATCATCTTCCCACTGGTCTGCTAGATCGATGTCGTCGTCGTCCTCCAGCGTCGGGCGCACTCGTTTCAGGTGCTCGATGATGCTGTCGTAGACCGTGCGTCGAAGGTCGACGCCCTCAGGGGCGGGCCGCGCCCCGGAGCGCCCGGTCGAGCTCTCGGCATCGTCATCGGCGTCGCTCCGCCGTTCCTTCGACTTGGTGCGTTGCACCAGCATCCCGTCGGAGGCGCGCACCCGATGCGCTGGCGACCGGGCGGCCGCGCCGAGGGCCTGCTCGCCGTCGTCGCGTGACGGCTGTCCTCGGCGCGACGCTCGAGCGGCCATCGCGTCCGCTTCCGCCTCCAGCGCCGGCTCGTCGTTGAGCGCCACGCCCTTCATCTGGGCCGTCGCCCGCACCCTTCCTTCCCGCTGCTGCACCACGTGCGCGAGCTCGTGCCCGAGGAGCTCCTGCCCTCGCGCCGTCTGAGGCGTCCAGTGCCCCGGCGCCACATGGACGTCGCTGCCCTGCGTGTACGCCTGCGCCCCCAGCGCCGTCGCGCGCGCCGAGCCCGGGTGGATCCGCACGTCCGAAAAATCGGCGGAAAACGCGCTCTCCATCCTCCGCTGCACCGCCGCCGGCATCCGCTGCCCCGGGGTCGGCGCGGGCACACCTGTCCCGGCCCGTAGCCCCGGTTCGCACAGGTCGTGCACTGCACCGGCGCGGCCGGACGGGAACGCCGCGCGCCGCTGCAGCGCCACCCCCGCGGCCTCCTTCGCCGTCGTCCGCTCCGGCGCGCGGGAAGCCGCCTCCTTGGCGGTCATCCGTCCGCCCGGAGCTCCCGCTCCCCAGCCCTCCAGGACAGCGGAGCCCGCGCTCCTCGCCGGCCCGAGCGCGCCGCCCTCGCCGGACTCGCGGCGTCCTCCACGCGATTCCAGGTTGGGTCCCCTGCGGAGCTCCAAGGCCATGCGAATCCCTCCGTCACGAGCCCATTCAAGAAGCAGACCTCCTGTCCCCTCGCGCCTGGCAGCGCCGGCCCACGCCCGTCGATGCGCCGTGCAACACCCGACGTTGCACATCGCCACGCCACGGCGGCGCGCATCCCGACGTCGCGCGCGTTTCGCGCCTCATCCCCCGGCACGGGTCGTGATGGCTACGCCGCCGAGGGTGAGCTCGCGGACGCGGGCCGGAGGTGAGCTGTGGCCGAGAAGTCGATGGAACGCGCGGGGACCACGAACAGACAAGATTACGCCAAGCTGGCGCGAGAGGCGGAAGAGCGGCTCAACAAGGCAGAGACACAGCGAGAAGAGGCGCAGATGCGAGCAGACACGGACGAGCTGAAGGCGCGGATCGAGCAGCTCGAGGCCGAGATCAACAAGGCGGAGGCCGAGGAGATCAAGCGGCGTCAGGCCGCCGAGAAATCGCTGGAGGACGCCAGGAAGCCCTTCGACGAGGCGAAGAAGAAGTGGGACGCGGCGAAGCGGCCCCGCGAAGAGGCCGAGATCAAGGAGCGCGAGGCGCAGAGCGCCTATCGCATCGCCGCGGCGGAGTTCGAGCGGGTGAACGCGCGGATCCACCGCGAGATGACCGAGGCCGAGCTCGCCAGGGCGAAGGCCGTCGCCGAGGCGAGGAAGGAACAGCAGCGCCTCGCCGAGGAGATCGACGAGCGCGAGTCCAGGGGGTCGGGCCCTCCGGGGAGCTGCGCCCCCCAGCGCTCGCAGCACTGAGCGCGGCCGGCGCAAGGCGGCGCCCGGGCGCGGACCGCGCAGCGCCCGAGGACGCGCGCCCGGCGCCGCGCGCGCAGCTGCCAGCGCGATCGTGCTGGTCGACACCGCATCCACAGGCGCTGCTCTCGCGAGCAGGGCCGCGAGCGAGCGCCTGGCCACCTGGCCGACGCGCGCCGACACCGAAGCTCGGCTCACGCATTCTGTGGGAAGCGCCGGTCTGTCGGCGACAACGCGTCTGTGAAGATCCTCTCTTATCGCCGTTTGGACTTCACAGCTGGCGTCGCTTGCGATTCCAGGTCGAGCGATGTAGATTCGGCGCTCGCGGTCGGTGAGTCGTGGGTCGAAGGGGGAAAGCCACGATGCCCGCTATCAGAGGTGGATCTGCGCGCCCGGACGGCGCGCCCGGGCAGCCCGCGCCTCGCGCTGCCCCGCGAGGAGCGCCGGTGTCGAGCATCCTTGTCGTCATCCCGGGGGAGCTCGGCCGGACCGTGGCGCGCGCGCTGCGCGCGCTGCGCTCGCTCGAGGACGGACTGCCGCCGCTCGACGTCGCCCTGATCGAGCCCGGCGATCTCGCGGCGTCGCCGCCCGCCGCGGACCTCGTCATCGTCGACGGCCCGCTGCCGGCCGGGGCGCAAGGCGCGCTCGGGGAGGGGACGCCGGTGCTGGCGCTCGGCCGCGAGGCGAAGGAGCCGTTCGCCCCCGGGCCGCTGCGCGACGCCGTGCTGGCCGCGGTGGAGCGCGCGGAGTTCGGGGGGATCGTCGCCGTCGATCCGCCCCTGCGCGCGGCGCTGCGGGTGATCGAGATCGCCGCGCCCCGCCGCGCCGGCGTGCTCGTCACCGGTCCGACCGGCGTCGGCAAGGAGCTGCTCGCGCAGCGGCTGCACCGGCGCTCCGGGCGCCCGGGCGCGTTCGTGGCGATCAACTGCGCCGCGCTCACGGACGGCCTCGTCGAGAGCACGCTCTTCGGGCACGTGCGTGGCGCCTTCACCGGCGCGGTGTCGACCGTGCCAGGCGCGTTCGTGGAGGCGCAGCAGGGCACGTTGTTCCTCGACGAGTTCGGCGATCTGGCCCCCGCGATCCAGGCGAAGCTCCTGCGCGCGCTGGAGTACGGCGAGGTGCGGCCCGTGGGCGGCGCGCGAACGACGTCCGTCGACGTGCGGGTCGTGGCGGCCACGAACCGGGACCTGATGCGCGAGGTGGAGCGATCGCGCTTCCGGGCCGATCTCTACTATCGCCTGGCCACGTTCGTGATCGACATCCCGCCGCTGTGCGATCGGCCGCGGGACCTGGCCGCGCTCGCGCGCAAGCTGTCGGCCGAGCACGAGCGCAGCGGCGCCGTGACGCTCTCGGGGGAGGCGGAGCATCTGCTCCTCGCCTACCCGTGGCCGGGGAACGTGCGCGAGCTGCGCAACGTGATCGAGCGGGTGCTGTCGCTGGCCCGCGACGGGGCGGTCGGGGTCGAGGAGCTCCTGCGGCTCGCGCCGGAGCTGTCCGCGGTGCGCCAGCGCGACGCGGCCGGCGGGACGCTGGCCGACGTCGAGCGCCGGCGGATCCTCGAGGTGCTGCGGGACGGGGGAGCGCGCGGGCAGGTGGCCGACGCCCTCGGCATCCACCGCACCACGCTGTGGCGGCGGCTGAAGCGGATGAGCGCGCCCGGCGACAGCGCGCCGCCGCCTTCTGGAGAGCAGGCCCGCGGCGACGGCGCGCCGGACACGCCCCCGCCGCGGAGCCGGCGGCGGCTCACCTGAGGCGCCTGCCGCCGGGCGCGTCGGCGGCGAGGAGCGCGTCGAGGTCGGCGCGCGGGCAGAGCCGATCGAGCTTCGTGTACTCGGCGAGGAGCGCCGCGGCGAGGTGCGTCCGCCGGATCGGCGCGCCCTCGGCCGCGGCCCGGTAGGCCGCGGACAGCGCGGCGTTCCGGATCGCGCCCCCGGGCAGCTCGAACCGGCGGGCGAGCGCCCCGAGGTCCACGCCCGCGTCGACCGGCGCGCGCGGCGGGATCGACAGCCGCCAGATCCGCTCCCGCGCGGCGGCGTCCGGCTCCGGGAGCTCGATGACGTGGTGGAGCCGGCGCGCGAACGCCTCGTCCATGTTGCCCTTCAGGTTGGTGGCGAGGAGCACGACGCCCTCGTGCTCCTCGATGCGCTGGAGGAGGTAGTTGGTCTCCAGGTTGGCGTACCGGTCCGTGGCGGTGCCGACGGTGGTGCGCCGGCCGAACAGGCCGTCCGCCTCGTCGAAGAACAGGACGGCGTGGGCGCGGTCCGCCTCGTCGAACAGGCGCGCGAGGTGCTGCTCCGTCTCGCCGATCCACTTGGAGAGGATCCGGGACGCGTCGATCCGGAAGAGCGGCATGGCGAGCTCGCCGGCGAGCACCTCGGCCGCGAGCGTCTTGCCGGTGCCGGGCCTGCCGAACAGCAGCGCCTTGACGCCCCGCCCGAGCGCGTGGTGCTGCGCGAAGCCCCACGCCTCGTCGACGAGCGCGCGGTGCGCGACGTGGGCCGCGACGGCGCGCAGCGCGTCGAGCGCGGGCGCCGGCAGGACCAGCCGGTCCCAGCCCGGCCGCGCCGGGCGCAGGGCGGCGAGGTCGCGCAGGCGGCTCTGGGTCGCGAGGCGGCACGCCGCCTCGACCCCGAGGGAGCGGGCCTGCGCGGCGGCGCGGTGGATGCGGCCGGGCGTGAAGGCGTAGCGCTCGGCGGCCCGCTGGATCTCGGCGTCCGGCAGCGCGCCGCCCGACGCCGCGCGCCAGAGGGCCGCGCGCTCGGCGGCGGGGGGCGTGCCGAGCTCCAGCAGGGCGAGGGGCCGCGCGCACAGGGGCTCGGGGACCAGGGCGCCCGCGTCGAGGAGCAGGGCGAGGGGCACGTCGCCGGCGGCGGCGAGCTCCTCGGCGGCGGCGTCGCCGAGCGGGCCGCGGACCGCGAGCCGCGCCCCGAGGATGCGCGCCTCGCGGAGCGCGATCGTCAGGAGGGGCGCCGCGCCGCCGGGGCGCGCGGCTGCGTCGCCGGCGCGGATCGCCGCGTCGCCGGCGCGCATCTCGAGCAGGAGCAGGGGGCGCCGCTCGCGCGCGGCGAGCGCGAGCGCGGCCGTCCGGCGGCCCGAGCCGGCGGGGCCGCTGGCGACGAGGGTCGCGTCGGGGGCGACCCCCTCGACGCGCGCGGCGAGGGCGGGCGGCGCCTCGCCGGGCGGCACGAGGGCGCACGCGCCGGCGGGGGTCGCGAGCGGCGACCAGCGCGCGGCGGCGGCGAACGTCGCGACGCGCGGATCGAGCGAGAGCGCGCCGTCGGGCCCGGCGCCGTCGACGTCGACGACGAGGCCGCGGCGGAGGGGGCGCGACGCGTCGAGCGCGAGGGCGACGCCGGTCGGGTCGTTGAGGAGCTCGGCGGCGGCGGCGTGGGTCGGGCGCGTGCGCTGGAGCGCGTCGTGGACGTGGCCGACGAGCGCGCCGACGCGCGGCTCGATCGCCCAGGCGACGAGGAGGCGCAGGAGGTCGCGCTCGGCGCGGCCGAGGCCGAGGCCGCGCTCGACGCGGCCGAGCGGCTCGTCGGGCTGGTCGTCGAGGAGGCGGTCGAGGGCGGCGCGGGCGCGCGCGGCGGCGCCTCCGGGGTCGAGGCCCGCGGGCGGGGGGCACGGCGCGGCGAGCTCCGCGAGCTGGGCGACGGTGCGGGCGACCTCCTCCGCGGGCGCGTAGGGGGCGTCGCTGGCGATGCCGGCGCGGCGGCGGGCGAGGGCCTCCGCGATCGCGTGCGCGGTGAAGCCGACGGCGAGGGCGAGCGCGGGGCGCGCGAGCGGGGGGGTGGGCGCGTCGGGGGACGGCGGCGCGAGGGCGGTGGGGTCGGCGCGGTGCGGGGCAGGGGGCATGGCGGGGGTCTCCTCCTCGGTCCTGCGCTCACTCCTGCTCGCCGAACGCGAAGCGGAGCGGGCCCTCGTCGAGCCATGGGACCTGCGCGATGTCGAAGGACAGTCCAGCGCGCAGGAGCGCCTCGTAGCCCCGCGTGAACGGCAGGCGCACCTCGAGCGCTGCCTCGGTGCGCCGGAGGACGCCGGGGATGGCGATGACGTCCTGGGCGAGGTCCTCGGCGCCTGCAGGGAAGCCCGCGAGCCGGAGGCGCGCCTGCGCGACGGCCGCGCGCGCCCAGGCGGCGCACGCGGCGTCGTGGGTCGACGCGGCGTCGAGAGGCGCGGCGCCATCGAGGGCGGCGCGGGCGAGGGCGGCGCAGCGGTCCGGGGTCCACGAGGCGGCCTCGGCCTCGCGTTCCTCGGGGGCGGGAGCGTCGAGGAGGCCGGCGAGCATCCAGGCGGCCGGGTCGTCGGCCCATTCCTCGCCGAGCTCCGCGGCGAGGATGCGGCGGAGGACCGCGCAAAGGGCGAGGGTGGGCTCCGGCTGGATGGCCTCGACGGCGTGGGCCCACCCGAGGTCGAGCAGCGGGCGGACGAGGAACGCGAGGCCGGCGGCTCGGGAGAAGATCGCCGTCTCCTCGGGCGGGAGGTCCGGAAGCACGAGCGAGACGTCGGGGCGGGCCGCGAACGGCGACGGCGCGAGCGGGTCGGTCGCCGCCGAGACGGGTGCGGCGGCTGCCGACGGGCGCGCTGGCCGAGGCGTCGCGCCTGCGGGAGGGACAGATGGGGGGCCTGAGGCGGGCTGCGAGGGCGTCGGAGCGGCCTGCGAGGGCGTCGGAGCGGCCTGCGAAGGCGTCGAGGCGGCGGCGCCGACGAGCTGCTCGATCGTGGCGAGCGCGTGCCCGCGAAGGGATGGCGCACCGAGCAGGGCTGCGGGCGTGCTGCGGCACAGCTCGGCGAAGGCGAGCACCAGCTTCACGGCCGGTGGAAGATGCGCGGGATCGATGCGTGGCCCCGGCGGGCCGGCATCGGACGTGAGGAGGGCGTTCAGGGCGGGGGCGTCGCTCGCGTCGACCCAGCCGGCCGCGGTCAGATCGCGCAGTGCCCGCGACTCCGCAGCTCGAAGCGCGCCGGCAGCTTGCGGCTGCGCCGCGAGGCGCGGACCCGCCTCGAGCAGCTCCGCGTGAACGCAGGCGAGCAACGCGCGCGCGGTGGGCTCGTCGAGCTGTCCGACCAGCTCGGACAGGCAACGGCGGCGGGCTAGGCGGCCGAGCTCGGCGAGAGGGCGGGCAGCCATGAGCATCGTGCTGCGCCTCGGGTCGTCGGCCGCCACGGCGAGCGTCCGCGGCTCGGTGCGCAGCACCGGCGGCTCGACGCTCCGTGCCGGGGGTGGTTGCGGCGCCACGCGCCTCTCGGGCCTCGCCCTGTCGGCGCGGGAGACGGCCGCGCCCCGAGCGCCCCGCGCAGGAGGGGGCTCCGCCGTGATGGCGCCTCCCGCATCCCTGTCCCGGCGCGCGTCCACCCGATCCTCGTCGACCCCGTGCGCCGCAGGGGGCGACCCGCCCAGCGCGGACTCCGTTGGCGCGGCGCTTCGATCCGGCGGAGCCTGCTGGCGAGGCTCGGCAGGCGCGAGGCGCCCGGCAGGTCCCCCGGCGGCGTCTTCCGCGTCGGGCGCCTCTGGCAGGGCGCCGGGATCGCCCGCGGCATCGATGGCGCCAGGATCCGCGAGATCGATCGCGTCGAGCCCATGGCGCGCGATGACGGCGAGCACGGCAGCGCGCCATGCGCGCGATCGGGCGAGCGCGCCCCGGCCCGTCCGGCTCATCTCGGCCAGGGCGAGCACGAGCTGCACCGGCGCGGCGAGGGCCTCGCCGGCCCACGCGATCGCGCGGAGGGCGCGCGCCCTGGCCGACTCGATCCGCGCCATGGCGGCCTCACGAAGCGACGGGGCGCCCGCGAGCGCGCCGTCGCCGCAGTCGGCGAGCTCCTCGACCACGCGTTCGAGCAGGGACAGGGCCGCTGCGGCACCCGGGGCACGTGAGCCGCGGGGCGAGGGGCGCGCCGCGCCGCCGGTGGGCCGCCCGGCGCCGTCGGCCAGCCCCGCGGCGTCGGCGCCGCCCGCGGCGTCGGCGCCGCCCGTGGCATCGGCATCGGCACCGCCTGCGGCGCCGACGCCCATCGCCAGCGCGAGCGCCTCCGCCAGACAGCCGAGGAGGCGCGCCCGGGCCAGGCGGCCTAGCAGCGCCAGCGGGCGAGGCGCGCGGAGCGCCGCGGCGATGAGCGCGCCGGGGGAGGTGTGCGCGCCCTCCGGCGAAGTCCGCCTGAGCGCGGCCCACCGCGGCTCACGCCCCCCCGCTTCGCTGGGAACCAGGGCCGTGCTCGGCGCCGCCGCGTCGAGCTCCGGCCGGCGATCCCGGCCCTCGAGCGGCGCCGCCGGCCGCCCGAGCAGCGCGGCGACCGCGGCGGCGGGCTGGCCGGCGCGCGCGGCCTGCGCGGCAGCGTGGAGCAGACGCGCGCGGCTCGCGGGGACGCGCGCCGGCACGGGAGGGCGATCGACCGCTTCGCGCGGCGAGGTCGGGTCGCGGGCGCAGAACGCCGCCTGCGCGATCGCGTCCGCCAGCGCGCGGGCGACCGCGTCGGCGGGCGACTCGCCCGCCAGGACGGCGACGCGGAGGTGGATCGACAGGCGCGGGAGGACCATCGCCTCCGGGAGATCGGGCAAGGCGTCGAGCAGGCGCTCCAGCGCCGCGAGCACGGCCCCGACGAACGCATCCGCGGCGGCGACCGGCGCGGGCACGCCGCGGACGTGCAGCCGGAGCCGGGCGATCGCGACCTCGGCCGTCATGTCCGCGCTCCGCAGCCCATCCGGCCGGCGGGGGGCTTCCCTCCGCCGGCCGCTCCGCCGCGGCGACCCTCGTCTTCCGGCGCCATCGCCCCGTTCCCCGTCAGCCGAGGCACACCAGCACGCGGATCTCTCCGCCCCCCTCGACGGCCTCGAGCGCCTTCGCCACCAGCGTGCCGGTCCGCGGCTCCTCGGCGCGCGACAGCGCGCCCTCTTCCTCGCCGATCGTGAGCCAGTCCCCCGGCCGGACCGCGCCCGTGACCCGCGCCCGCGCCGCGCCGGAGACGACCACCCTGGCCCTGGTTCCCTCGGCGCTCGCCACCACCCCGAGCACCCTGGCCTGCTCCTTCCTGCTGGCCGGCCGCACGCCCGTCTCGCCCCACGTCACCGCCCGGCGCGGCAGCGAGGCGGCGTCCCCCTCGGCCTGCAGCTCGCAGGCGAGCCCCTCCTGCGCGACGAGCCCGCCGGTGAAGAAGGCCTGGGCGTGGTGCACCGCCTCGTGGTGGAAGTGCACGCCGCGCACCGGGTCGAGCTCGATCGCGACCGCGAGCTCGCCGCCTTGCGCCGCCCTCCACGCGCGCGGGTGCGCGAGCGCCGCGCCGACCAGGCCGGCGTGCTGCACGCCCGCCGCCGGCTCGGGCGCCGCGCGCGCCGCGGGCTCGGCGCGGGCCCCGGGCTCCGCTGCCGGCGCCGCGCGGTGCGGCGGTCGCGCCGCGGCGCGCACGCTGGCCCGGCCCTCGCCGTCGAAATCCACGTAGCCGAGGCGCACCCGGCCCTGACCGGGGCCGCGCTGCTCCCCGAGCGCCGCGTGCGGCGAGAGGCGCGGCCCCTCGCGGCGACCCGCGGGCTCCGGCGGCCTGGGCTCCGCCTCGAGGTCGATCCGGTGCCCCTCGACGATCCAGCGCTCGGACGGCCGATCGCCGAACACGCCGCGGAGCTCCGCCTCCTCGCGCTCCGCGTACGCGAGGTACACCGCGTAGCTCGCGTCGCGCGCGCTCCGGCCGGGGAGCAGCGCGGAGAGGTCCTCCGGGCTCCGGACCACGATCGCCCGGCCGTCGCCGCCGAAGGCCACCCCGGGCTCGACGCGGACGATCTCGCCCCGCGCCTCGGTGCGCACCACCCCGAGCTCCAGGCCGAACGCGACGCCGAACATGTCGCGGGCGAGCGAGCGCCGCTCGAGCGCCGCGCGGAAGTAGTCCTGATCGGCCGACAGCTGCTCGGCGCCGAGCACCTGCCCGTTCTCGTAGGCGACGCGGATGCGATCGGCCATGGCTCAGCACCCCCCCCGCGACCGCAGCGCCGCCTCGAGCTCGTTCACGCGCCGCCTCAGCGCCTCGAGCTCGTCGCCGCCCGCGCCCGGCGCGCCGCCGCGCCCGCCGTCCCGGCCGACCTCCGGGGCGGCGCACGGCGCGGACGCGGCCGGCGGCGCCTGCTCCAGCTCCGCGCGCGCGTCCGCGGGCGCGCCCCGGAGGAGGCGCTCGAGCATCCACGCGACGAGGTACGTCAGGTCGGCGTTCGACAGCACCGGCCGCCGCAGCGGCCGGACCTCGACGATCGATCGGCCGGCGACCTGCGCGAACCGCACCTCCCCGAGCGCGACGAGCGCCTCGCCGCGGGCCGGCGGGAACGCCACGCCGGCGATCACGTCGAGGATCGCCCCCACCCCGGCGTCGGGCGGGCCGTGCTCCGCCGGCGCCGCGCCGATGCCCGCGATCGCCGCCGCGTTGCGCGGCAGGTTCCAGCGCCGCGCCAGCCAGTCGGCGTACGTCTGCGCCCCGGCCCCGCCCCGCACGCCGACGGGCGGGGTGCAGACGTCGGAAGAGCGTCGTGGCGCCGGGACGGCGCAGCGCCGCAGGCGTCGTGGGGCGCCCCTGCCTCGGGCGCCCGCGCCTCGTGGGCCCGCGCCTCGTGCGCCTCGGCGCACGGGTCGGGGAGGCAGCCGGACACCCAGTATTCGTCGGGCAGGCGGGCGAGCCACACGAACCGCACCCGCTCCTCGACGCGCGCATGGTCGCCGCCCGGCTCCGCGCCCGGCGCGCACCCCGCGCTGTACCTCGGCTGGAGCGCCGCGAGGTGGTCGTCGTAGACCGCCGCCAGCACGAAGGTCTCGTCGTCCGGCGAGCCCGAGGGCTCGGCGCCCGAGGCGCGGCGCGCATCCCCGACGTGCGCGCGCTCCGGCCGGACGAGGCGCGCGGTGCCGCCGTGGACCAGCGCGCGGCCCCGCGCGTCGAGCGCGACCCCGGGGCCGACGCGGACGGCGCACGCGTCGGCGTCGGGCGACAGCGCGTAGCCGCCGTAGACACCCCACCCCGCGGTGACCGTGGCCGCGAGGCGCTGGGCGAGGCGGGCATGGTCGACGATCGCGCGCAGGTCGGCGTCGGTCACGAGCTGCCCTGGAAAGAAGCGGGGCCGCGGGGGCAGGCAGGGCGCGGCCGGGGGGCCCGGGCGACGCGTCGCCTCCTCGGTGCCCGACCGGCACGCGGCGCCGGGGAGCGCGCAGCGCGAGCAACCCTCGCAGCCGCAGCCGCAGGCGCGCCGGGACCAGGGGGAGCGCTCCTCGGCGACCGCGCCGGCGCAGCCGCAGGGGCGGGAGAGCAGCGGCGCGGTCATCGCCCCCTCCGCGCGAGGTGGAGCGCGTGCCGCGCGAGCCCGGCGATCAGCGCCGTGGGCAGGAGCAGGGGGCGGATCGCGCAGTTGTCGACGTCGAGCACCTCGCCGCCGGGCACCACGCGGACGCGGGCCAGACCCGCGCAGCCGTGGCGCTCGCGGCAGCCCCCCGCGGCGTGCGCCGGCGCCTCGTCGAGGATGAAGTCGCAGAGGAGCGTGTCGAGCCGCTCCCGCTCGCACCGGTGCAGGCGGTCGAGGAGCCGGCCCACCGCCCCCGGCTCAGGATCGGGCGGATCCGCGGAGACGTCGATCCGGAACCCGTGCCGCACGCGCGACGGTGCGCACGCCGGCGCGCACCCGCCCTCGGGCGCCCCGAGCGCCTGGATGGGCCGCTCCGGCGCCTCGTCGTAGCAGAGCGACAGGTAGACCTCGACCGGCTCGGGATCGCAGCGCCCCGCGCGCGACGGCGCCCGCGCGTCCTCCCGCCCGAGCCGCTCCCCGCGCCGCGAGAGCGCCCTCGCCGCGGCGTCGCGCAGCGAGACGCGCACGTCCTTCTCCACCCGGATCTCCCGGCCCAGGCAGTCGATCGCGACCCCGCGGCGCACGAGCACCGCCTCGCAGCCCTCGGCCGCGTCGACCCGGAGGCCGGCGGCGGTGCCGCAGCCGTGCAGCTCGGCGAGGTGGCGGCGGGCGTTCCCGAGGTGGAGCTGCTGCTCCTCGGTCATGTCCTGCGCCTCGAGGAGCATGCCGTAGAAGTACCGGTTGCGGGTGACGGCGCTCGGGTGGAACGCGGGCCCGGGAGGCTCGTGTTCGTGCGGGCGAGGCCGGTCGGTAGGGTCGTGCGTGGGCATGCGCTCTCCTTGCGTTGCGTGACTTGCGAGACCTTCGTGGTTCTCGTGACCTGCGTTGCGATCAGAGCTTCGCGTCCGTCCCGAGCCGCGGACCGAGGCCGAGCGCGAGCTCGCCGGACCCGCGCGCGAGCAGCGGGGGGCCAGGCGCCGCGGGCTCCCCGGCGCCCGGCAGGCGGAAGGGCGGACGGCGGCCGAGCGCCGCGTCCAGGCCGAGCCGACCCTGGCCGAGCGCGGCGCGCGCGGCCGCGCCGAGGACGTGCACCCGCGTCCCGGCCGGCGCCTCCCGCTCCGCCGCGCGCCGCACGCGGGCGATCCGCTCGGGCGAGGCGCCCGCGGACGGCGGCAAGTAGACGAGGATCTCGCCGCGCCCCGGCAGCAGCGGCTCCACCGCCGCGCCGTCGCCCCGCTCGAGGCGCGCCGCGCCGAGCATCGGCTCGCGGCCGAGCACGGCCCGCGGCGGGCGGCCGGCGTGGGGCAGCACCGTGGCGCAGCCGAGGGGCAGCGCGCCGCCGAGCAGGAGCGCCGCGCCGCGCTGCCCCGCCTCGACCACGCGGACGCCCGGGCCCGCGTACCACCCGAGCACCTCCTCCAGCGCGGCGCGCGTGCCGCGCCGGCGGTGGACGTGGATCGCCGCCGCGAGCACCGCCCGCTGCTGCGGGACCGGCCACGCGGGGTCGAGCTCCACGCCGAGGCGCTCGGCCAGCCACGGCAGCCAGCCGGGATCGGCCGAGAGCGGCGCGAACAGCCGCCCGAGGCGCGCGATCGACGCGCCGAGATCCACCTCCGCGGCCTCGAACAGCGACAGGAGCCGCGCGGTCAGGTCCCGGCCGGCCGGATCCTCGCTGTAGATCGCGGGCAGGTAGCGCAGGTACGACGCGCGCGGGTGCTCGACGCGGACCCACCGGACGAAGGGCGTCTGCCGCCCGTCGCCGTGGAGCGTCAGCCGCACCCAGGCGCACCGGCCCAGCGCGCCCCGCAGCGCGACCTCGGCCGGCCGCCCCGGCGCGGGCGCGACGAGCTCCGCGGCCGGCGTCCAGCGCGGGTCGTCCTCCGCCGCCTCCGCGGCGATCGGATCCCAGCCCTCGCGCTCGTCGGGCTCGTCGACGGCGAGGACCTCCACCCGCACGCCGGACGCGGCCGACGGCGTCGGATCCACGAGCGCCGTCACCCGGTGCCACTCGGTGTCGGGCAGCCCGGCGTCGAGCGGACCGAGCACCACCCGGCCCTCGCGCGCGTGAAACCCCTCGGCCTCGAGCGTCACCGGGCGCACCGCGCAGCCCGCGCCGAGCCCGAAGAGCGCGCCGCCGCGGTACGCGAGCGCGCTCCACGCGTCGGCGGCGGCGCTCCAGCCCGTGGGCACGGCCTCGCCCCCGCGCACGCGCCACCGCACGACGCGGCCGGAGCGCTGGTCGCCGATGAACAGGAACACCTCGTCCGCGGCCGTCGGAGAGGCCCGATCGAAGGCGATGGCGGGCAGCGCCGGGCGGCCCAGGTCGATCTCGGCGAGCGGCGCGCCGCCGCGGCCGAGCCGGAGCCGCGCGTCGCCGGCCCGGACGACGGCGACGAGGCCGTCGCCCGCGGCGGCGATCGCGTCGCCCTCCGCGCCGCGCACCGCGACGACCTCGACGCCGGCGCTGTTCCCCGCGCGCGCGGGGCCGTCCGCGAGGTCGAGCACGAACACCCTGCTCCGCGCGTCGAGGGCGATGCCGCCGGGCCGGCCCACGGGGATCCGCGCGACCTCGCCCGGCGGGGACAGGCGCACGACCCGCACCTCGCCCTCGTCCTGCAGCGCCAGGAACATCCGCCCCCGGGCGTCGACGGCGATCCCGCCGATCCGGCGCTGCGCGCCGTCCGGCAGCCCCCAGCACGAAGGCGGCGGCTCCGCGCGCCCGGCGACGAGGCACAGGCCCCGCCCGCCCTCCGCCGCGGCGAACGGCGCCCCGGCCGCGTCGAAGGCGAGCCCCCGCGCCTCGGCGCGCCCCGGCCGGACCAGCTGCCCGGGCGGCAGCCCCGCGGGCGGCAGGTGCAGGCCGCGGCGATCGAACACGACCCCCCGGGGGGGCACGCTGCGGGCGAAGCGCCACCCGTTCCAGCCGTCGAGGTGGAAGAAGCGCGCCGCGGCGACGCCGGACGGACGCATGGCCTACCTCCGGTGCTCCGGCGCGCGGACGCGCACCGCGTGCTCGCCCGACGCCGCCACGTCGAGCTCCGATCCCAGGGGGATGTCCTCGCACGGCGGCTGCGGGACGCCGTCGAGCGCCACGGAGAGGCACCGGATCGCGGCGACCCCCGGCGCGCCGTGGACGATCTCGCGCAGCTCGCCCTGCGCGATCGGGGCGCCGAGGGGCCAGCCCGTGCCCTCGTACCCGCCGGTGAGCGGGTCGAGGTAGCGCCGCAGCCCCGCCGCCACCGCCTCGCGGGCCGGCGCCGCGTCCGCCTCGCGCGCCACCTCGATCTCCACCGTGACGTCGACGCGGCGGTAGCGCGGCCCGACCACGAACAGCTCGGTGGTGAGCACGCGGTAGGGCTCGAGCGCGGCCGCGACCCGGTCGAGGAGCTCCTGGGTCGGCGCGGGCGCGGCGTCGTCGCCCGCGCGGGGCGGCACGACCACCAGCGTGAGCGCCCCCGTGACCGGCGCGCGCGGGTACAGCGGGTGGCGGCGGCTCAGCGCGACGGCCCGGGCCACGCCCGCGCGATCCACGGCGAGCGTCTCGAAGTCGGCCGGCGTGACCGCGCGCTCCAGGGCGTGGAGGCGCGCCGGCGCCCGCTCGCGCGCCTCGTCCGCCGGCTCCTCGTCCGCCCCGCCCGAGGCGGGCTCGCGCTGCTCCGGCTCGGGCGCCGCGAGCCCCGGCAGATCCACGCCCGGCGCGAGCCGCAGCCGCGCCCCGTTGCCGGCCGCGCCGCCGCCCGACCGGTAGGTGATGCGCAGGTTGTTCTGCCCGCGCGGCGGGATGAGGCCGTCGATCCCGTCGCCGAACGCGACGCCCGTGCGGTCCTCGAGCGCGCGGAAGACCCGCAGCGGGTGGCCGTCCGGCGCGACGCCGCCGCCGCCCTCCGGTCGGCGCGTCGCCAGGTCGTCCACGAGGTGCCAGGGCTGGAACGCGCGCGCGTCGCCCTCGGCGCCGCCGCCGGTGGGCTCCTCCACCTCGACCTCGGGCGGCCGCTCCGGGTCGAGCAGGATCGGCGGGTTGTGCACGAAGCGGACCTGGTTCGGCGTCCCGTCGCTCCCCGGCTGGAGCAGCTCGCGGACGACCGTGCGCCACTGCCGGACGCGCAGCGCGTTGATCGCGAGCCAGCGGATCCGCCGCGGCGCTGGGGCGCCCGGCGCCGCCGGGACCGCGCGGATCCAGATCCGCGCGCGGCCCTCGAGGTCGCCCACCTCGACGCCGGCCGCGAGCCGGCGGGTCAGCGCGACGCGCACGAGCCCGCTGCGGCGCAGGCCGCGCGTCTCGTCGCCGGCCACCTCGAGCCGCTCCCACGCCCCCGGGCCGACCCGGCCCTCCCACGCGACGCCGCCCTCGAGCAGCTCGGGGCGCCCGCCGCCCCGCGGCGCCGAGGCCGCCGACCCCGGCGACGTCGTGCCGAGGAGGCGCCCGGCCTCCTCCTCGACGCGGACGAACAGGTGCAGCTCCGCCTCCTCGAACCGCCCGGTGATCTCCGGCGCGCGCCCCGGGGCGGCCGCGTCGAGCCCGAGGTAGAGCGCGCGCCCCGCGCCGCCGGCCTCCCCGAACGGCGCATAGGGCGCGTCGCCCCGCCGGTTCGCCTCGGTCGCGTCGGCCGGCGCCGGGCTCATGCCGTCGTCGACGAGCACCGCGCCGAGCGCCGCGCCGATCAGCGACACGTCGGCCTCGGCTTCGAAGCGGACGTCCTCGTCGCCGTCCTGGGCGCCCTCCGCGACGAAGCCCACCTCGTGGGCCGCGCGCGCGACCGGCGGGGCGCCGGGGCGCATCTGCAGGGCCACGATCGCCTCGGCCGAGCGCGCCGGCGCGGGGCCGAGGCCGACGAGGTTGAGGAACGCGGCGTACATCCGCTCGTCGGGCGCCTGGTTCAGCCGGAAGATCGCCGTCTCCATGAGCCAGGCGAAGAGCTGGAGCAGGGTGATGCCCGGGTCGCTCTCGTTGTGGTCGGTCCACTCCGGCAGGTACGCGGGGATCCGGCGGCGGAGCTCGGCGAAGAGCTCCTCGTACGAGCGGTCGTCGAGGTTCTTGAGGGCGAAGGGCATATCAGGGCTCCTCCGGGCCTTCTCGCAGGTAGAGCGGATAGACCATGTTCATCACGGCGTTGACCTCGCGGAGCCGGTACGACAGCGACGCGATGAGCCGCGTCTCCACCTCCGGGTCGGGCTCCACGGCGACGTCCAGCACATCGATGCGCGGCTCCCAGCGGGCGAGCGCGCCCCGGATGGCCGATTGGATGCGCGCCGCGGTCGCCGCGGTGCTCGGCTCGAAGAGCAGCGACGGCACCTCGGCGCCGAACGGCGCGAGCATGACGCGCTCGCCGAGCCTCGTGCCCAGGATGATGCGGATCGCCTCCTCCACGTCTTCTTGCCCGTCGACCATCGCGAACCGCCCCCGCCGATCCAGCCGGATCGGGAAGGCCCAGCCGCGCCCGAGCTCCCTGCGCAGCATCCGCGTCACCTCTCGATCTTCACGATCTGGGAGAGGAGCGACGCGAGCCCGCTTATTTGCCCCGTGAAGGCAACAGCGTTCACCGGCGGCGACGTCGGACCCGCGGCGGATCCGTGGGTGTGCAAGGCGAGCTGATTCAAGAGCTGCGTCAAGAGCCGATTCAGCGCGTTGCCGAGCACCGCGGGCTGCAGCGCGTTCGCGCCCCCGAGGCGGACATCGCCGCTCTCGAGCGTGATCTTCCCGCCCGGCGGCGTGTCGGCCAGGGTGATCCGGTGCCCTCCGGGGGACTGGAGCACGCGCACGTCGATATCCCGTCGCATGGGCGGCGGGTTCCTCTCCGAATAGGTCGATCCGAGGATGAGCGGCAGCTTCGGGTCGCCCTCGATGAAGCCGACGATCACCTCGTCCCCCTCCTCCGGGATCGCCTTGAACCCGTGCGCGCTGCCCCCGACGGCGGCCCTGGCGCCGCCCCTTCGACCCCTGGGGGCGCCGCCATCGGCGCCCCCGGGGGCGCCCTGCTGGTCGGCCCCGGACGCGCCCCCGTAGGGCACCAGCACGCGCGCCCAGCCGCTCTCGATACCGAGCGTCGGATACCGGACCCGCACGCGGCCGAGGTTCTGCGGATCCCGTCGATCGATGACGACGCCGATCATCGTCCCAAACTGCTTGCCGGCCTGCATCACACGTATGCCTTTCTCACGTGGATCGTGGTCTGATAGCCGCCCTCGTCGATCGTGTGGGTCGATTCGGTGATGTAGTACTTGCCGTCGAAGATCTTCCCGAGCCCCGTGAGCTCCACGTTCCTGCCGGCGCGGAGCAGCGGGACGCCGACGGTCTGCGCGGTCCCGGTCACGAACGGATCGCTCGATCGCTCGAGCACGGAGTGCGCCAGCGCCTTCGCGTCGGCCGCGGTGAGCACGCCCTCGGACGTGATGATCTCCCGCTTGTCCCGCCGGAAGAGCTCCCGGACCAGATCGTCCGCCGGCCGCCGGCCGGGAGGCACCTCTTCCGCGTCGAGCCGCCGCTCGGTGACCTCGATGAGCTCACCCGAGTACGGGTGCCACGCGCGCACGGTCACCTCGGAGACCTGCTTGGCGAACGTGAGCGTGGGCGAGAACGACACGAGCGACGTGCCCCACTCGAGCCGCAGCGCCACCGGGTCCTGCCCCTCGCGCGACTGGACGAAGCAGAGCTCGTCGCAGCACGCGTAGACCTCGAAGTTGATGCGCCTGGCGCGCTCGACCAAGAACGCGAGATCATCCATGTTCTGCTGCGGGACGACCCCGTCGGGCGTCGGCAACCGCTCGCCGGTGTCGAGCGTCCTGTCCACCCGCGCCCTCATGCCGTAGCTCGCGGCGATCGCGGTCGCGATGTCGGCGTCGTTGTCCTTCCAGGACACGCTCTTCGGCTGGTTGCGCATCTCGTGCAGCCGATCGAGCCCGCGGACGGTGATGGTGGGGGCGCCCGACGCCGGGAAGCTCGGGTCGAGCGCGGTGATCACCCCCGTGATCATGAGCTCCATCGGGGGCCCGTCCTCATACCCCATCTCGATCTCGACGCGGCTCCCGGGGCGGATCGCGGCGAAATCCTCCGTGTACTTGAAGCCGGGCCGCCGCCGCCCCCCGCCGTCGTCCCAGTTGTTGAGCACGAGCGTGAAGCCGGAGAGCTCCGAGATGCTGTCGGACACCTCGACGCTCAGGAAGTCCGAGCCGGCCGCGTGCAGCTCCCGGCCGTCGATCAGCACCCGGTAGCGCGGCACGTAGAACGAGGTGTCCGGCCACCTCTCCGGCGCGAGCTCGGGGACGGTCGGCGCCCTGCCTCCCGGCCTCGGCCGCGGCTCCCTCCGGCACGCCCGGCCCGGCGCAGGCCGGCCCGGCCGGACAGGCGGCGGGCGACGGTTCGGCGGCGGCACGTCAGCCTCCCCCCGGGCCGGCCGGCCGCGCCGCGGGCGGCTCGATGGGGGGCACCGTGAGGATCCGGCCCGGCGCGAGCCGCGCGGGATCGGCGATGCGGTTGTGCTCCGCGATCGGCCGCCACTGCGTCGGGTCGCCGTAGGCGCGGGCCGCGATCCCCGGCAGCGTGTCGCCCTCGCGCACGAGCACCGTCCGCGTCCGATCGGGCGACCGCCGGCTCATGTCGCCGATCTGCTCCGCGAGCGTCCGGTAGCGCTTCACGCCGAGCGTGACCCGGATCCGGCGCGGCGTGCCGTCCGGATCGAAGAGGACGAACTGCCGGCTCGCCGACGCCACCACCCCCCTCAGGATCTCACCGCCCCACGAGAACGTGCACACCGGCGGCGCGTGCAGCTCCGGGGCGACGCGCGCGAGCTCCATGAGCTGGTCCGCGGGCCTGCGCGCGTCGCGCGGCCCCCGCCCGTCGGTCGTGTCGACGAGCAGCTCCAGCGAGAGATCCTCGCTGTTGCCCCGCACGAACTGGAGGATCGGCGCCTCGAGCCCGGGGACGCCGATCTCGGCGAGCTGGTTCGACTGCGCGATCGTGTACTCCGTCGGGTTGAAGAGCACGTTGATCGGCCGAAACGACGTGTTCGTCGTGATGCGCATCTTCGCGAGGGTCTGCGGGGCCGGCATCACTCCCCCCCGAGGCGGCGCGGGTCGCGCTGGTTGATCTTCCGCTCGCGCGCGAAGCGCTCCGCCGCGAGCCGCCGGATCCGGGCGGCGTCGTCCTCGGCGGTGGGCGTCGCGTGGCCGGGCCGGTGCGGAGCTCCGGCCTCGCTGTCGAGCTCGATGCGCGCGTCGATGTCCCCGATGATGAGCGGCACGGTTCCCCCCTCCCTCGTCGCGCGTCAGCCCGCGCGCAGCCCCTCGTGGGCGATGGTGAGCGACTCCATGGCCACCGCGCTCTGGGTCGCGGACAGCGCGGGCCCCGACCAGCGGACCGGGATCCCGCGCTCGAAGCGCCACGCCTGCGATCTCCTCCCGTCGGCCGAGTACACCCGGATCTCCCCGCCGCGGCGCTGGTAGTTGCCGGCGCCGATCGCCTCGATCCAGGCCCAGAGCTCGCTCGGGACCGGCACGAGGCCCCGGCGCAGGACGAGGTCGGCGGGGCGCAGGCGCGTGGGCAGCTTGTGCACGAAGCGGTTCTGGCCGCCCTCGGCGAACTCGAAGAGCTCGTGCTCCACCTCGAGGCCCGAGCACTCGGCGAAGCCGGCGGCGGCGCGCGCGCCCTCGAGCACGACCCGGTAACGGAACGCGGTGAGCAGCTCAGGCATCGCGGCCTCCAGGCGCCCCGACGTCGTCGAGGATCTCCGTCGCGTCGCGCGAGAGCGCGATGCGGATGGTCAAGAACTCGAGCGGCACGGCCAGCGCCACGTCCACCTCGGCGATGAGCCGCCCCGCCGCGACCGACGCGGGCGGGTTGAGCGCCGCGTCGCAGCGCACCGCGTAGGCCTCGGCCGGCGTCGCGCCCGCGAAGGCGCCCTGCGCGAGGAGCTCGCGCAGCGCCGCGTGGATCGCGACCCGCGCGCGCGCCTGGAGCAGCTCGTCGTTGGGCTCGAACGCGAGCTGCTCGCCCACGACCCGGAGCACGCGCCGGAGGTACGCGAGCACGCGCGCCCCGGGGACGTAGCGGTCGGGGCCGGGGCTCCTCCGCACCGTCCGCTCGCCGAAGACCACGACCCCGCGGCCGGCGATGACCCGGATCGCGGTGACCCCGAGGTCGTTGAGATCGGCCCGGTGGCCCTCGAGGAGCGGCCGCTGGACCGCGATCGCGCCCTCGAGGCGCTCGTCGGCGAAGCGGGCCGCCGGGCCGCCCTGGCGCGTCCTCCGCGCGAGCAGCCCGGCGACGTGCCCCGACGGCGGCACGAGCGCGCTGCGCTGCCCCGGCGCGCGCGGATCGAGGATGCGGATCCACGGGTAGAGCAAGGTCCCGAGCCCGCCGGTGCGCGCCCCCGGCTCGGCCTCGAGGAGCGTGCGCTCGAGCGCCTCGGCCCGGTCGATCGCGTCGAACACCGCCATGCCGGGCTCCGGATCGAGCAGGGCGATGCGCTCGCGGCCGTCGGCGGTGCCGGCCAGCGCGGCCACGAGCGCCCGCTGGAGCGCGCCCACGGCGGCGCCGTAGCCGGGCAGCCCGGAGGCGGGCGCCGACGCGCCGGAGCTGCCGGAGCCGCCGGGGCCCGCGCCTCCGGCGTTGCCTCCGGCGTCGAAAGCGCCCTGGCCGGCCGCCGGCCCGGGCCGCCGCCGCGGCGGGGCAGGGGGCGGGGCGCAGGGAGGGGGCGGCGGCGGCTCGGGCTCGAGCCGCACGTCGGGCCGGTCGTCGGGGCACGCCGGCTCGTCCGGCGCGAGCGGCAGCATCAGCTCGGGCGCGCAGACGATGCTCGGCGCCGGGTGGAGCGCGAGCGCCTCGAACGCCGCGAGGAACGCGGGCGCGTCGACGCCGCCGAGGTCGTCGAGCCCCCCGGAGAGCTCCGCCACGAGCTCGTCGCGCCCTGCGCCGCCCGGCGGCGCCTCGGCCGGGTCCTCCACGAAGGGAAGCTCGTCCGGGGCCGCGAGCTCGCTGCGGACGAGCGCCGACGCCGCGGGGCCCTGGAAGGCGAGCGCCCGCGCGAGCGCCGGCGCGACCGGCCGCCAGGTCGGCGGGACGGCCGGCGTCCACCAGAAGGACAGCGGCCGGCGCACGGCGAGGAAGCGCCAGAGGTAGCGCGGGTGCGACGGCAGGAGCGAGAGGTTCCGGAAGCGCTCGCGCGCGCCCGCGCCCTCGATGGTGACGTCGACCAGGGGATCGAGGCGCTCGACGAGGAGCGGCGGCCGCGGCAGGCGCGCGTCCGGGAGGGTGAGGCCCCGCCCGTACGGCGCCTCGGCGAGCAGGCCCATCGCGGCGCGCCCGCCGACCCCGGTGATGCGGACGAGGTCCCCCGCCTGGAAGCCGCTCGACGGGGGCAGCGGCAGCCCTCCGAGCACGCGGGCGCGCCGCCGCACCGCGAGCGGCGCGCGCAGGGTCACGCCGTTGGCCCAGGCGCCGGGAGACGAGGCCCCGAGGTCGATCCGGCGGCCGGTGGCCGGGTGCGCGGCGGTCGCCGCCCGCATCCGCGGGGAGGCGAGGCGGAACAGCACGCACGGCCCGCCGCCGTTCTGGAAGAAGCCGTGGAGGGCCAGCGGCGAGAGGGCCTGGCGCCCCGGGGCGCCGGGGATCGGGACGAACCCGCCGTACATCGCGCGGTACTCCCCCCAGTCCTCGACGCGGACCGGGACGAGCGCCGGGCCGCGCTCGAAGATCCCGGCGAAGCCGGCGATGTCGGCCCGCAGCGCGAGCGAGAGGTCGGGCGCTCGCGCCGGTCCAACGAACTCGATCCCCGGGGCGCGCATACGTCAACCGGGCTGGATCTCTTCGTAGGCGATCTCGAGCGACTCGACCGCCGTCTCGCTGCGGTTCGCCGCCAGCGTCGGCCCGGACCATTTCACCGGCCACGCCCGCATGAGCTTCCAGGTCGTCACGGGGGCGCTCCCCTTCTCGTCCATGAGCTGGATCGTCACGGACGCCCCGGTGCGGTCGCCGTCGGCGAGGCCCTCGATCACGCGCCTGCGCCAGTTGAAGAGATCGGAGGCCCCCGCCTTGAGCACCCCGCGCCGCAGCACGAGGTTCGGCTTCTTGGAGAGCCCCGGGATCTTCTGCGTCTCGTCGGGCTTCATCTCCCCGCTCCGGTACTCGACGACGTCCTGCTCGGTCTCGAGCCCGCTCACCTCCGAGAACCCTCCGGTGATGGACGCGCCGCCACCCTGGATCTCGACCTTGAAATTGAATGCGTTGTAAGGAGCCCTCGGCAT

Protein sequences of DBSCAN-SWA_1

>NC_021658|3821356:3869024|3826148_3826553_-|WP_148314787.1|DBSCAN-SWA
MTDQPATATASATLAIPLDGLTITAPPPEMLSQKNVESVTGIPARVFLDTIRAPGFPLPVTKLGKLRLVPREAFVAYLRALAEEPASRRDAEAEERTRVAAVLATAGLEPVPCPRTGRASAPRDAASRGRLPQK
>NC_021658|3821356:3869024|3837226_3837898_-|WP_020734714.1|DBSCAN-SWA
MIVQLGKASVTWTRADLEAKLAGHARVLIDVGTGDGRFVYRSAGAHPDTYCIGVDPAGERMREVSWRASRKPARGGRPNALFVVASVQALPEELAGLAHTLTLNFPWASLLSALVLPEAPVLEALRRLVRPGGELIALLNQSVFDDRPYAARLGLPELSDAWLDDALRPAYRAAGFEIRTSEIVDGEVPHQTSWGQHLTLASGRRTRLLTAEAIGGSASAAPG
>NC_021658|3821356:3869024|3863923_3865156_-|WP_044985807.1|DBSCAN-SWA
MPPPNRRPPPVRPGRPAPGRACRREPRPRPGGRAPTVPELAPERWPDTSFYVPRYRVLIDGRELHAAGSDFLSVEVSDSISELSGFTLVLNNWDDGGGRRRPGFKYTEDFAAIRPGSRVEIEMGYEDGPPMELMITGVITALDPSFPASGAPTITVRGLDRLHEMRNQPKSVSWKDNDADIATAIAASYGMRARVDRTLDTGERLPTPDGVVPQQNMDDLAFLVERARRINFEVYACCDELCFVQSREGQDPVALRLEWGTSLVSFSPTLTFAKQVSEVTVRAWHPYSGELIEVTERRLDAEEVPPGRRPADDLVRELFRRDKREIITSEGVLTAADAKALAHSVLERSSDPFVTGTAQTVGVPLLRAGRNVELTGLGKIFDGKYYITESTHTIDEGGYQTTIHVRKAYV
>NC_021658|3821356:3869024|3856431_3856821_-|WP_187345930.1|DBSCAN-SWA
MGAILDVIAGVAFPPARGEALVALGEVRFAQVAGRSIVEVRPLRRPVLSNADLTYLVAWMLERLLRGAPADARAELEQAPPAASAPCAAPEVGRDGGRGGAPGAGGDELEALRRRVNELEAALRSRGGC
>NC_021658|3821356:3869024|3843485_3844586_-|WP_020734718.1|DBSCAN-SWA
MSTEEPLPIADLSRIPAHIAGPAAWYGPAMARGDGWIEHLTPAEVEEVEAAVRRFGETGADPAQIRAEGFPLPTLAARLRRVLAEVLDGRGFALLRGLRGRWLDRGGRDDLRAAAIAFLGIGSHLGSARSQNARGHVLGHVKDLGLSSQDPSVRIYQTRERQTFHTDSCDVVALLCLRTARAGGLSALVSSVTLYNEMRRARPDLAEALFAPIETDRRGEVPAGERPYFRIPVLNWHAGLLSAIYQRQYIESARRFPDVPPLTARQVEALDLFDALADDPALHMTMELRPGDIQLVHNHTLLHDRTAFEDWPEPDRKRHLLRLWLAPPGARPLPPVFRERFGSLTPGDRGGIVVPGARLHAPLAPA
>NC_021658|3821356:3869024|3848928_3850233_+|WP_020734722.1|DBSCAN-SWA
MSSILVVIPGELGRTVARALRALRSLEDGLPPLDVALIEPGDLAASPPAADLVIVDGPLPAGAQGALGEGTPVLALGREAKEPFAPGPLRDAVLAAVERAEFGGIVAVDPPLRAALRVIEIAAPRRAGVLVTGPTGVGKELLAQRLHRRSGRPGAFVAINCAALTDGLVESTLFGHVRGAFTGAVSTVPGAFVEAQQGTLFLDEFGDLAPAIQAKLLRALEYGEVRPVGGARTTSVDVRVVAATNRDLMREVERSRFRADLYYRLATFVIDIPPLCDRPRDLAALARKLSAEHERSGAVTLSGEAEHLLLAYPWPGNVRELRNVIERVLSLARDGAVGVEELLRLAPELSAVRQRDAAGGTLADVERRRILEVLRDGGARGQVADALGIHRTTLWRRLKRMSAPGDSAPPPSGEQARGDGAPDTPPPRSRRRLT
>NC_021658|3821356:3869024|3852365_3855161_-|WP_044985805.1|DBSCAN-SWA
MTAEVAIARLRLHVRGVPAPVAAADAFVGAVLAALERLLDALPDLPEAMVLPRLSIHLRVAVLAGESPADAVARALADAIAQAAFCARDPTSPREAVDRPPVPARVPASRARLLHAAAQAARAGQPAAAVAALLGRPAAPLEGRDRRPELDAAAPSTALVPSEAGGREPRWAALRRTSPEGAHTSPGALIAAALRAPRPLALLGRLARARLLGCLAEALALAMGVGAAGGADADATGGADAAGGADAAGLADGAGRPTGGAARPSPRGSRAPGAAAALSLLERVVEELADCGDGALAGAPSLREAAMARIESARARALRAIAWAGEALAAPVQLVLALAEMSRTGRGALARSRAWRAAVLAVIARHGLDAIDLADPGAIDAAGDPGALPEAPDAEDAAGGPAGRLAPAEPRQQAPPDRSAAPTESALGGSPPAAHGVDEDRVDARRDRDAGGAITAEPPPARGARGAAVSRADRARPERRVAPQPPPARSVEPPVLRTEPRTLAVAADDPRRSTMLMAARPLAELGRLARRRCLSELVGQLDEPTARALLACVHAELLEAGPRLAAQPQAAGALRAAESRALRDLTAAGWVDASDAPALNALLTSDAGPPGPRIDPAHLPPAVKLVLAFAELCRSTPAALLGAPSLRGHALATIEQLVGAAASTPSQAAPTPSQAAPTPSQPASGPPSVPPAGATPRPARPSAAAAPVSAATDPLAPSPFAARPDVSLVLPDLPPEETAIFSRAAGLAFLVRPLLDLGWAHAVEAIQPEPTLALCAVLRRILAAELGEEWADDPAAWMLAGLLDAPAPEEREAEAASWTPDRCAALARAALDGAAPLDAASTHDAACAAWARAAVAQARLRLAGFPAGAEDLAQDVIAIPGVLRRTEAALEVRLPFTRGYEALLRAGLSFDIAQVPWLDEGPLRFAFGEQE
>NC_021658|3821356:3869024|3823082_3824033_+|WP_020734703.1|DBSCAN-SWA
MLLASYNHLDPVMSSLLVDVVATAGLLALAVLALRLSLRLRRATALADASFRANVALGPGEGVVLGTVEREQGADVAVRVEVEQKGVELASSVSWRHGGAVSWRHAWTETGRKVRAHPFYLRHASGARVRVEPGEDVMLVDALDGMILVDRTKRVRVAELVPGEEAFAFGELRRAPDPEAPPLGYRERAQGYVLVRPRRRRMLLSSEPFGEQFARKAAFRLRWAIIAGVASLAFNAAFAPFHARRWLGETVEVRVTQLRESDDDRGSFDVTMLGPHGVAFSDEVPIPTSTGSAGAGDCWRRATSRRGRQPARSAPT
>NC_021658|3821356:3869024|3829699_3831340_-|WP_044988147.1|DBSCAN-SWA
MGSLSRRCAVKSVAAVAVCVWGASMLTSCSSYSDDCWERLECPPDPEPPPDPCEGHPAAAPALDMCGVFVSPLSGDDSSPGTKDAPVKTLQHAIGLAAHGRGDGEKRTGRVFACGGLLEEEITLPSGVDLWGGRRCDDGDWSYQGSFGGPDHPTIIAPPGGIPLRVLGAEGTALAGDNATSVIAGVQIVAANASTPDDKSSIAMILSAGARAIVSDSKIIAGDGKDGEPGGDAFSVRAMAGVVGINGANACTADATVGALPVVTVCGDGIESTGGYGGDGGLDVGGDGAPGQPALGGNSERDGHAGLGADRTRCEDGGDGADGADGGRADGAFGPGFLSEDGWIGVRGEDGKKGGVGQGGGGGGGSKSRGPMFACPTSGLQSGAAGGSGGSGGCGGKGGRGGGYGGASIGIVALEGTDLTVTDTDVFTGKGGQGGVGGTGQPGGAGHHGAPGGITLVDGMWDACKGGDGGNGGRGGDAGGGLGGASVGIAYVVPNFAIRPGTTIVPGDAGAGGPAGNAGPEDEVGKGKTGPQAALYAFPAASEPIH
>NC_021658|3821356:3869024|3841310_3842171_+|WP_044988150.1|DBSCAN-SWA
MQRAPTSWEIDPDDPRAPPQELWDRMTPEERQRVLDTLPSEFEVSEASPPEGDFHFNPKVAARDTLGGYFQRIGRRVYLACELPVYYPAERMFAPDLIAVLDVEVQERAHWSVSAEGKGVDLALEILWSGRSKKDLADNVARYASLGISEYFVFDRRRRQLRGFRLVQSSGRYQPIVPQEGRLTSAVLALDLGLDGDRLRFFHGQDALPETRELLDRLGTMVGDLEARIERTELRLDEERRRLDEERQRADEAQQQLNEERQRADEAERRLAEALAELTRLKGERR
>NC_021658|3821356:3869024|3844592_3845528_-|WP_020734719.1|DBSCAN-SWA
MATPEDPRDSRREAALGVAYGVAAYSAWGVVPVFWKQLRHVGAVEILAHRTVWSLLAFAVLTLATGQLRALGAALRDRRVVGAMAATGALVSANWVLFIYAVAVGRVLDASLGYFINPLLSVLLGMVFLRERLRPAQWLALGLAAAGVVHLAVRAGAVPWIALALAGTFGVYGLLRKVVAVNALPGSTLETLFVAPLGAAYLATLHAQGAGAMGRVDLRTDLLLAATGVITALPLVWFTNAARRLSLTTLGFLQYLAPSGQFLLAVLVYGEPFTATQAVSFACIWTGLAVFSADAALRARASTAARTSLGM
>NC_021658|3821356:3869024|3824113_3826183_-|WP_148313545.1|integrase|DBSCAN-SWA
MPRAVVGCRRSRAGPLGARTPGEPLIDPRITGDRSMTDVPQRRAGAKRSPAIPSASLPASTDRRTRRSRSAGRPSLPAEAAASDAGPRDLASPTQRPKPTARAAGEKRANGSGSVRLRGRTWTARLSLGDAGRRTFSLPTCRTEQEANGRLEVLSELAGRLLAAGQIVIGVPLLEQAAAREGTALRDVRLAIDHLCKGEARPRSSGDTTFAEFAERVLSGQLAEQYPLHVKALRHPEQYRHKLNHVLGVLGPVPLPRVTVDHADSAVSMPPGHLEASSRQGIAKVIHRILALATYPARIIANNPLPRGWVPKADNNKAKSSLYPDEDGRLMAAVDIPLSYRIYYGFLIREGMRADEAGRLEPSDLDLDRGAVVLDENKTDDPRAWALSPDVVRALRVYFAMCPPKQRVFSRPSGLPLPGRDGAKSFRDHLRCAGIERPELFETTESRLNIRLHDTRATFITIKLANGRTETWISDRTGHRSSNQIHNYKRAARKVAELGLGDFAPLNEAIPELRGKGRAVGGARLSEGAEAGAAGEGRFLGAAPPGQTPASADVPAASAAEDEAAADGAALGPRWATPAPTAAAEQPEPIEMVDFSSARPASARKYRQELSVGAERSPESSANKPSHRHRAPRARRSLATDGPKLPDHESSGGGFPRVPFRALLVPPRGRLALGQPAAPVLDQLLLVPG
>NC_021658|3821356:3869024|3866465_3868565_-|WP_020734736.1|tail|DBSCAN-SWA
MRAPGIEFVGPARAPDLSLALRADIAGFAGIFERGPALVPVRVEDWGEYRAMYGGFVPIPGAPGRQALSPLALHGFFQNGGGPCVLFRLASPRMRAATAAHPATGRRIDLGASSPGAWANGVTLRAPLAVRRRARVLGGLPLPPSSGFQAGDLVRITGVGGRAAMGLLAEAPYGRGLTLPDARLPRPPLLVERLDPLVDVTIEGAGARERFRNLSLLPSHPRYLWRFLAVRRPLSFWWTPAVPPTWRPVAPALARALAFQGPAASALVRSELAAPDELPFVEDPAEAPPGGAGRDELVAELSGGLDDLGGVDAPAFLAAFEALALHPAPSIVCAPELMLPLAPDEPACPDDRPDVRLEPEPPPPPPCAPPPAPPRRRPGPAAGQGAFDAGGNAGGAGPGGSGSSGASAPASGLPGYGAAVGALQRALVAALAGTADGRERIALLDPEPGMAVFDAIDRAEALERTLLEAEPGARTGGLGTLLYPWIRILDPRAPGQRSALVPPSGHVAGLLARRTRQGGPAARFADERLEGAIAVQRPLLEGHRADLNDLGVTAIRVIAGRGVVVFGERTVRRSPGPDRYVPGARVLAYLRRVLRVVGEQLAFEPNDELLQARARVAIHAALRELLAQGAFAGATPAEAYAVRCDAALNPPASVAAGRLIAEVDVALAVPLEFLTIRIALSRDATEILDDVGAPGGRDA
>NC_021658|3821356:3869024|3866047_3866473_-|WP_020734735.1|tail|DBSCAN-SWA
MPELLTAFRYRVVLEGARAAAGFAECSGLEVEHELFEFAEGGQNRFVHKLPTRLRPADLVLRRGLVPVPSELWAWIEAIGAGNYQRRGGEIRVYSADGRRSQAWRFERGIPVRWSGPALSATQSAVAMESLTIAHEGLRAG
>NC_021658|3821356:3869024|3857764_3858616_-|WP_020734727.1|DBSCAN-SWA
MPTHDPTDRPRPHEHEPPGPAFHPSAVTRNRYFYGMLLEAQDMTEEQQLHLGNARRHLAELHGCGTAAGLRVDAAEGCEAVLVRRGVAIDCLGREIRVEKDVRVSLRDAAARALSRRGERLGREDARAPSRAGRCDPEPVEVYLSLCYDEAPERPIQALGAPEGGCAPACAPSRVRHGFRIDVSADPPDPEPGAVGRLLDRLHRCERERLDTLLCDFILDEAPAHAAGGCRERHGCAGLARVRVVPGGEVLDVDNCAIRPLLLPTALIAGLARHALHLARRGR
>NC_021658|3821356:3869024|3858677_3860756_-|WP_020734728.1|DBSCAN-SWA
MRPSGVAAARFFHLDGWNGWRFARSVPPRGVVFDRRGLHLPPAGLPPGQLVRPGRAEARGLAFDAAGAPFAAAEGGRGLCLVAGRAEPPPSCWGLPDGAQRRIGGIAVDARGRMFLALQDEGEVRVVRLSPPGEVARIPVGRPGGIALDARSRVFVLDLADGPARAGNSAGVEVVAVRGAEGDAIAAAGDGLVAVVRAGDARLRLGRGGAPLAEIDLGRPALPAIAFDRASPTAADEVFLFIGDQRSGRVVRWRVRGGEAVPTGWSAAADAWSALAYRGGALFGLGAGCAVRPVTLEAEGFHAREGRVVLGPLDAGLPDTEWHRVTALVDPTPSAASGVRVEVLAVDEPDEREGWDPIAAEAAEDDPRWTPAAELVAPAPGRPAEVALRGALGRCAWVRLTLHGDGRQTPFVRWVRVEHPRASYLRYLPAIYSEDPAGRDLTARLLSLFEAAEVDLGASIARLGRLFAPLSADPGWLPWLAERLGVELDPAWPVPQQRAVLAAAIHVHRRRGTRAALEEVLGWYAGPGVRVVEAGQRGAALLLGGALPLGCATVLPHAGRPPRAVLGREPMLGAARLERGDGAAVEPLLPGRGEILVYLPPSAGASPERIARVRRAAEREAPAGTRVHVLGAAARAALGQGRLGLDAALGRRPPFRLPGAGEPAAPGPPLLARGSGELALGLGPRLGTDAKL
>NC_021658|3821356:3869024|3837931_3840544_-|WP_044988149.1|DBSCAN-SWA
MTEKTGGPGRDVLTQKEAEERAARIGNARYELSLDLSRGDGGYRGEAIAYFDVRGSGDTFIDFRGRRIERLEINGVPVEPEWSDCRIRLPGKLLDPETRVRVVYENDYDHTGDGFHHFRDPEDGEDYLYSDLEPFSAHRLFPCFDQPDIKASYRLSVTAPEDWEVIGNARIRRTIGAGLGRSTRVFEETTRFSTYIFALIAGPYSGVRDEHRGIPLGLYCRRSLEKHLDPDELFTITKQGFDFYPEFFDYPYPFTKYDQVFVPEFNAGAMENAGAVTHSERMIFRDPPTDHQRLTRAEVFLHEMAHMWFGNLVTMRWWNDLWLNESFATYMAFLAMEQATRFQPAVWKAFNVMKSWAYRQDQLVTTHPIAGELADTEHTFLNFDGITYGKGAAAMKQLVAAIGLPAFRDGMRRYFKRYQYGNATLREFLSALEEGSARDLGAWSRVWLEQASLNTLTAEWEPDGDRIGRLRVLQTAPEDYPTLRPHRIDVALAREEGGALVVDAVPAEIDGAATEVAAARGQRAPLFVFPNHNDLTFAKIALDPGSLAFVREHMGRVEDPLLRQLLWSSLWSMVRDQKLASPAYLALVRDKLPVEPDLSLVEPVLSNAVTALARYVPDPMREVEASAFTALALAALRAAPRGDAQIVWARALLNAAYAAPDLALAARLVDGEIAVEGLEIDQEMRWTVAVKWIARGMAGADARLAAERERDPSDRGQRAALRAETARPDPAAKAAAWERFHEGGYGSLHLTSAAMSGFNWSFQRALLEPYVQGFFERVQQVFETRTHELASAYFTHLFPSYRVDRDLLAAAEARLAALQRAPDGAAPRLPMLVRMLRESIDDLARAIGCRELAAASAPQSARAGSGGAPR
>NC_021658|3821356:3869024|3860759_3862838_-|WP_020734729.1|plate|DBSCAN-SWA
MPFALKNLDDRSYEELFAELRRRIPAYLPEWTDHNESDPGITLLQLFAWLMETAIFRLNQAPDERMYAAFLNLVGLGPAPARSAEAIVALQMRPGAPPVARAAHEVGFVAEGAQDGDEDVRFEAEADVSLIGAALGAVLVDDGMSPAPADATEANRRGDAPYAPFGEAGGAGRALYLGLDAAAPGRAPEITGRFEEAELHLFVRVEEEAGRLLGTTSPGSAASAPRGGGRPELLEGGVAWEGRVGPGAWERLEVAGDETRGLRRSGLVRVALTRRLAAGVEVGDLEGRARIWIRAVPAAPGAPAPRRIRWLAINALRVRQWRTVVRELLQPGSDGTPNQVRFVHNPPILLDPERPPEVEVEEPTGGGAEGDARAFQPWHLVDDLATRRPEGGGGVAPDGHPLRVFRALEDRTGVAFGDGIDGLIPPRGQNNLRITYRSGGGAAGNGARLRLAPGVDLPGLAAPEPEQREPASGGADEEPADEARERAPARLHALERAVTPADFETLAVDRAGVARAVALSRRHPLYPRAPVTGALTLVVVPPRAGDDAAPAPTQELLDRVAAALEPYRVLTTELFVVGPRYRRVDVTVEIEVAREADAAPAREAVAAGLRRYLDPLTGGYEGTGWPLGAPIAQGELREIVHGAPGVAAIRCLSVALDGVPQPPCEDIPLGSELDVAASGEHAVRVRAPEHRR
>NC_021658|3821356:3869024|3834064_3835138_-|WP_020734709.1|DBSCAN-SWA
MLDTAIIGGGVCGLSLSRSLSAVGADYQLFEARDRLGGRVLSVPAGPTRVDLGPTWFWPVTQPLMSRLVDELELASFAQHDDGPIMVLSHPNKTPERYRGDTGLHGGGLRLVGGMGSLVDALAGAVPRERVHLGHVLEAVELDDAKVLLRFARGDGGLTVEARRVVLALPPRLLAENVRFTPELPAPLRQAMTATPTWMAAQAKAVLTYRQPSWREDGLSGNAFVTHGQAVFGEIFDASDPLHGLSALGAFLALPAGARARFAAELPLLIDKQIAQVFGEHLSRVEQHYKDWATDRFTCSARDREERPEHIGSGHPLLRQPYARGQVFFGAAETASYAAGYLEGALDAARRIRRDLA
>NC_021658|3821356:3869024|3868568_3869024_-|WP_020734737.1|tail|DBSCAN-SWA
MPRAPYNAFNFKVEIQGGGASITGGFSEVSGLETEQDVVEYRSGEMKPDETQKIPGLSKKPNLVLRRGVLKAGASDLFNWRRRVIEGLADGDRTGASVTIQLMDEKGSAPVTTWKLMRAWPVKWSGPTLAANRSETAVESLEIAYEEIQPG
>NC_021658|3821356:3869024|3831360_3832491_-|WP_044985803.1|DBSCAN-SWA
MRCGAHLLFILLTLGASTGLVSSADAQQRSPASGRSDGLTVKDLVRRARKARDRGSRTQAYEAYKAALDAANVPPGMKLDRAEVDRGAFDPAEIAGELGLCELELRKYRDAAEHLPWSLERDWALPSQLQERFLTGQRKAAFYVVELVLSVDPPDAEILIDGQKIGRTARTYELFLEPGRHMVRARAPGREDGFHAFNGEPGDKQEISMKLPGPAVSRAKEAPAVPKTARAMPTARAKEPDPWASWPGTLRVTGIAAATAGMSIGTILMIRAGRLDDDLTARRNRLLGEPSSSSSTCWKAPLNSPCAELARLQDARNLSGRAGVATVIAGGVVGAVTAASFFTDFSFLGFSPARDRIHVSPVATRNEIGAQIEALW
>NC_021658|3821356:3869024|3863249_3863897_-|WP_148313548.1|DBSCAN-SWA
MIGVVIDRRDPQNLGRVRVRYPTLGIESGWARVLVPYGGASGADQQGAPGGADGGAPRGRRGGARAAVGGSAHGFKAIPEEGDEVIVGFIEGDPKLPLILGSTYSERNPPPMRRDIDVRVLQSPGGHRITLADTPPGGKITLESGDVRLGGANALQPAVLGNALNRLLTQLLNQLALHTHGSAAGPTSPPVNAVAFTGQISGLASLLSQIVKIER
>NC_021658|3821356:3869024|3865831_3866023_-|WP_020734734.1|DBSCAN-SWA
MPLIIGDIDARIELDSEAGAPHRPGHATPTAEDDAARIRRLAAERFARERKINQRDPRRLGGE
>NC_021658|3821356:3869024|3850225_3852337_-|WP_020734723.1|DBSCAN-SWA
MPPAPHRADPTALAPPSPDAPTPPLARPALALAVGFTAHAIAEALARRRAGIASDAPYAPAEEVARTVAQLAELAAPCPPPAGLDPGGAAARARAALDRLLDDQPDEPLGRVERGLGLGRAERDLLRLLVAWAIEPRVGALVGHVHDALQRTRPTHAAAAELLNDPTGVALALDASRPLRRGLVVDVDGAGPDGALSLDPRVATFAAAARWSPLATPAGACALVPPGEAPPALAARVEGVAPDATLVASGPAGSGRRTAALALAARERRPLLLLEMRAGDAAIRAGDAAARPGGAAPLLTIALREARILGARLAVRGPLGDAAAEELAAAGDVPLALLLDAGALVPEPLCARPLALLELGTPPAAERAALWRAASGGALPDAEIQRAAERYAFTPGRIHRAAAQARSLGVEAACRLATQSRLRDLAALRPARPGWDRLVLPAPALDALRAVAAHVAHRALVDEAWGFAQHHALGRGVKALLFGRPGTGKTLAAEVLAGELAMPLFRIDASRILSKWIGETEQHLARLFDEADRAHAVLFFDEADGLFGRRTTVGTATDRYANLETNYLLQRIEEHEGVVLLATNLKGNMDEAFARRLHHVIELPEPDAAARERIWRLSIPPRAPVDAGVDLGALARRFELPGGAIRNAALSAAYRAAAEGAPIRRTHLAAALLAEYTKLDRLCPRADLDALLAADAPGGRRLR
>NC_021658|3821356:3869024|3856799_3857768_-|WP_020734726.1|DBSCAN-SWA
MTAPLLSRPCGCAGAVAEERSPWSRRACGCGCEGCSRCALPGAACRSGTEEATRRPGPPAAPCLPPRPRFFPGQLVTDADLRAIVDHARLAQRLAATVTAGWGVYGGYALSPDADACAVRVGPGVALDARGRALVHGGTARLVRPERAHVGDARRASGAEPSGSPDDETFVLAAVYDDHLAALQPRYSAGCAPGAEPGGDHARVEERVRFVWLARLPDEYWVSGCLPDPCAEAHEARAHEARAPEAGAPHDACGAAPSRRHDALPTSAPRPSACGAGPGRRRTPTGWRGAGTCRATRRRSRASARRRRSTARPTPGWGRSST
>NC_021658|3821356:3869024|3848074_3848485_+|WP_148313546.1|DBSCAN-SWA
MRADTDELKARIEQLEAEINKAEAEEIKRRQAAEKSLEDARKPFDEAKKKWDAAKRPREEAEIKEREAQSAYRIAAAEFERVNARIHREMTEAELARAKAVAEARKEQQRLAEEIDERESRGSGPPGSCAPQRSQH
>NC_021658|3821356:3869024|3842219_3843368_-|WP_063752130.1|DBSCAN-SWA
MLREAAHRRVRTPRPHGAGIRLAALFPMAPLPPARAAEECSGGDPGPAPVGGALVPAAPPAALNGPAARRARWKALLHAALAAFGLAALAALIRHVGAAEMLDAVIRAAPFLPFLVALEAARVGCEALATGLLCAPRRVPTAELLRIHAVSYPVMALMPAGRAAGEAVKAALLSPYVGAPRAAAIAAANQSLALLCAAPLSLLAAAALFRIGGGASPFALGVLAHAALLVASGLGVAFAARQRAASAWLTRRFARAGQLTVAFQEAVRERPPVPAWPFAACVAGRALQAAQYAVLLAAVGAESGLLRALAAYGVGAAGTAAGDLIPGQIGATDGAFTLAAPLLGLTASSAIAVSLLVHLLQAAFALAGIAAALAWRRSPPRR
>NC_021658|3821356:3869024|3821356_3822550_-|WP_148313544.1|protease|DBSCAN-SWA
MPTISRLRLGLLLAGLPASSLLPACSAAPVEGGDESDAADSQAIIGGVDAKSDALGAIGSLGVAVEAASEETGALDVQYRPFCSGALIGKSTVLTAKHCVDAARKMAAGGRVYFGVGFDGTHPDRTVDIVELGRAPGHEGGSVGFGRDVGVVHLDEEITDIEPAAMADLSDADIDTRFAAIGYGVQDNKKTFGTRKAGSVTLRAREGKVFELIFGSFEAFKQWATTRDRSELLAHLSAETEEEGNEGEAACDIDCLLRKYDEAILLAGYEALVGAGEGDAQPCHGDSGGPLVRIEGGRLRVYGVASGVISTNQLACDYGAVYATLGPEVLAFAKKASTWSDPCGDTKIDGVCEGRTAKRCTALDEGPRRVTKTDCSLLDQACGQDGTGAVACVDPGN
>NC_021658|3821356:3869024|3845761_3847582_-|WP_020734720.1|DBSCAN-SWA
MTAKEAASRAPERTTAKEAAGVALQRRAAFPSGRAGAVHDLCEPGLRAGTGVPAPTPGQRMPAAVQRRMESAFSADFSDVRIHPGSARATALGAQAYTQGSDVHVAPGHWTPQTARGQELLGHELAHVVQQREGRVRATAQMKGVALNDEPALEAEADAMAARASRRGQPSRDDGEQALGAAARSPAHRVRASDGMLVQRTKSKERRSDADDDAESSTGRSGARPAPEGVDLRRTVYDSIIEHLKRVRPTLEDDDDIDLADQWEDDANKLREESRELETAYEEANNRKSRVPLAKQLNGITRKLNQLLSNIKRTFSTTEGGFSALGRASELDVKIQDRSEPAPEGYTENTDFTRGTTLGGTLLSERFKVFKKTGEERASDAAAGKSVTVRGKPMDSEQPPPEGELKSLEEGLARVKSPQETQYSGSPRRKERDETQAKAMGNTNATGYAWLAGISGWKSSRWEWLHVRAASLGGVTDSTNLVVGTRDANTHMIPFESHVATLARLAADKGIYEPLKVTFSVEGQHGPAKHRVSKIKIEWNLEKKKEKDPSPLDVMFKKLGISGGAPESHGVAVFDPVHVGSSLSKDEVKRLEETLKDLRQGLLDQE
>NC_021658|3821356:3869024|3855261_3856428_-|WP_020734724.1|DBSCAN-SWA
MADRIRVAYENGQVLGAEQLSADQDYFRAALERRSLARDMFGVAFGLELGVVRTEARGEIVRVEPGVAFGGDGRAIVVRSPEDLSALLPGRSARDASYAVYLAYAEREEAELRGVFGDRPSERWIVEGHRIDLEAEPRPPEPAGRREGPRLSPHAALGEQRGPGQGRVRLGYVDFDGEGRASVRAAARPPHRAAPAAEPGARAEPAARAAPEPAAGVQHAGLVGAALAHPRAWRAAQGGELAVAIELDPVRGVHFHHEAVHHAQAFFTGGLVAQEGLACELQAEGDAASLPRRAVTWGETGVRPASRKEQARVLGVVASAEGTRARVVVSGAARARVTGAVRPGDWLTIGEEEGALSRAEEPRTGTLVAKALEAVEGGGEIRVLVCLG
>NC_021658|3821356:3869024|3865157_3865832_-|WP_044988159.1|DBSCAN-SWA
MPAPQTLAKMRITTNTSFRPINVLFNPTEYTIAQSNQLAEIGVPGLEAPILQFVRGNSEDLSLELLVDTTDGRGPRDARRPADQLMELARVAPELHAPPVCTFSWGGEILRGVVASASRQFVLFDPDGTPRRIRVTLGVKRYRTLAEQIGDMSRRSPDRTRTVLVREGDTLPGIAARAYGDPTQWRPIAEHNRIADPARLAPGRILTVPPIEPPAARPAGPGGG
>NC_021658|3821356:3869024|3835468_3835621_+|WP_020734710.1|DBSCAN-SWA
MPQRDRALLLRLGLDLDNPAHAELFVEGVRAADDDIADQVRWERERERLG
>NC_021658|3821356:3869024|3836012_3836903_-|WP_020734712.1|DBSCAN-SWA
MRPLPARRYELADWKHAKVNIDYCVCYDDRLYSVPYTLVGARVEIRATASVVELFHDSVRVASHARSYGRKGSAVIVDEHRPRAHRDYGKWPPERVVAWAETIGPNVGELARAVMRHRTHPETGYRTCLGVIRLADKYGRERVDAACARALRIGSPTAKSVTAILRNGLDRAPLVEPPPRGALQQLAVARADGTYANALAGLAKVAVLVLDDFLLAPMTDVERRDLLEVLEDRYDRSSTVTTSQIPTKSWHQAIGEASIADAICNRVVHNARLVTLRGGSMRQKKAVAPEVTETKT
>NC_021658|3821356:3869024|3862839_3863244_-|WP_044985806.1|DBSCAN-SWA
MLRRELGRGWAFPIRLDRRGRFAMVDGQEDVEEAIRIILGTRLGERVMLAPFGAEVPSLLFEPSTAATAARIQSAIRGALARWEPRIDVLDVAVEPDPEVETRLIASLSYRLREVNAVMNMVYPLYLREGPEEP

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148313544.1|3821356_3822550_-|protease	trypsin-like serine protease	NA	NA	NA	NA
3821938:3821955	attL	NA	NA	NA	NA
WP_020734703.1|3823082_3824033_+	hypothetical protein	NA	NA	NA	NA
WP_148313545.1|3824113_3826183_-|integrase	tyrosine-type recombinase/integrase	A0A1P8DJP8	Virus_Rctr16k	1.3e-71	39.5
WP_148314787.1|3826148_3826553_-	hypothetical protein	NA	NA	NA	NA
WP_044988147.1|3829699_3831340_-	hypothetical protein	NA	NA	NA	NA
WP_044985803.1|3831360_3832491_-	PEGA domain-containing protein	NA	NA	NA	NA
WP_020734709.1|3834064_3835138_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_020734710.1|3835468_3835621_+	hypothetical protein	NA	NA	NA	NA
WP_020734712.1|3836012_3836903_-	ATP-binding protein	K4I413	Acidithiobacillus_phage	1.6e-44	47.1
WP_020734714.1|3837226_3837898_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_044988149.1|3837931_3840544_-	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	9.0e-43	26.7
WP_044988150.1|3841310_3842171_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_063752130.1|3842219_3843368_-	flippase-like domain-containing protein	NA	NA	NA	NA
WP_020734718.1|3843485_3844586_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_020734719.1|3844592_3845528_-	EamA family transporter RarD	NA	NA	NA	NA
WP_020734720.1|3845761_3847582_-	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_148313546.1|3848074_3848485_+	hypothetical protein	NA	NA	NA	NA
WP_020734722.1|3848928_3850233_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_020734723.1|3850225_3852337_-	ATP-binding protein	A0A1C9EGA6	Acidianus_two-tailed_virus	2.6e-08	33.8
WP_044985805.1|3852365_3855161_-	hypothetical protein	NA	NA	NA	NA
WP_020734724.1|3855261_3856428_-	hypothetical protein	NA	NA	NA	NA
WP_187345930.1|3856431_3856821_-	hypothetical protein	NA	NA	NA	NA
WP_020734726.1|3856799_3857768_-	hypothetical protein	NA	NA	NA	NA
WP_020734727.1|3857764_3858616_-	hypothetical protein	NA	NA	NA	NA
WP_020734728.1|3858677_3860756_-	hypothetical protein	NA	NA	NA	NA
WP_020734729.1|3860759_3862838_-|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_044985806.1|3862839_3863244_-	GPW/gp25 family protein	NA	NA	NA	NA
WP_148313548.1|3863249_3863897_-	hypothetical protein	NA	NA	NA	NA
WP_044985807.1|3863923_3865156_-	phage late control D family protein	NA	NA	NA	NA
WP_044988159.1|3865157_3865832_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_020734734.1|3865831_3866023_-	hypothetical protein	NA	NA	NA	NA
WP_020734735.1|3866047_3866473_-|tail	phage tail protein	A0A059XP77	uncultured_phage	3.5e-05	27.7
WP_020734736.1|3866465_3868565_-|tail	phage tail sheath family protein	NA	NA	NA	NA
3868187:3868204	attR	NA	NA	NA	NA
WP_020734737.1|3868568_3869024_-|tail	phage tail protein	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_021658|7627900:7712487|DBSCAN-SWA
CTCAGACCTCGAGCGCGCTCTCGACGACGCGGTGCACGAGGCCGTACTCCTGGGCCTCGCGCGCGGTCATCCACAGGTTGCGCTCGGTCTCCTTGGCGATCTTCGCGGGATCCTGCCCGGTCGCCTCGGCGAAGATGCGGTTGAGCCGCTCGCGCGCGGCCATGATCTGGGCCGCCTCGATCTCGATGTCCGACGCGGGGCCGCGCACGCCGCCGAGCGGCTGGTGCAGGAGGAAGCGCGTGTTCGGGAGCGCGAACCGGTTCTCCCGCCGCGCGGCGACGAAGATCAGCGCGCCCGCGCTGGCGACCCACCCGGTGCCGATCACCTTGACCTCGGGCCGGATGAAGCGAATCACGTCGTAGATCGTATCTCCCGACTCCACGTGTCCTCCCGGCGAGTGGATCAGGACCCGGATCGGCGCCTCGCTCTGGTTCGCGAGGGCGAGGAGCTGCGCCGTGGTGGCCTGCGCCAGCTCGCTGGTGATCTCCCCGAAGATGAGGACGGTCCGGCTCCGGAGGAGGCTGCTCTGGACCTCCTCGGACAGCGCGCGGTGGGGCAGCTGTTCTTCGTTCGGCGTCGCATCGAAGCGCATCATGGCCCCGAGCATCCGGCCGCCCCCGCCCGCGCGCCATGACCGCGACGCGCGGAGTCATGCTCGCGCGTCTCGATCCGCGAGGGAGCGCTGGACGAGCGGCCTCGGCGCGGGCAACCATGGGGCATGGCGGACGAGACGGAGCGGCAGCTTCCCCGCGGCGTGGCGGTCTCCCGGCATCACGGCCCTCCTGGCGTGGTCTGGCGCGCGAGCGCTGGGGATCCTCCGAGCCTGCACGTCGTCGTGCAGGGCGCGTTTCGCCTCGCGCAGGACGGGGCGTGCACCCTGGACGGGGCGTGCGCCCTGGAGCTCGACGCCGGCGACCTCGTGCTCCTCGGGTTCGGCGCGCGCGGCGCCGGGCCCGGCGAGCAGCGCCTGTGCTGCGTCGCGCCGCCGACCGGCGCCGCTCCCGCGGCGGCGGAGGTGATCTCGGCGACCTACGCCGCTGCGCCCGGCGGGGCGCTCGCCTCGCTCGCGCCGCTGGTCCACCTCCCTGCCGGCGAGGTTCGGCGGGCGCCGGGGCTCTCGGCCGTGGTGGGGCTGCTGCGCGCCGCGCTCGCGGATCCATCCCCGGGACAGGCCGCGCTGGCGCGCTCGCTGCTCGAGCCGCTGCTCGCTTACGCGCTGCACTGCCACGAGCGGGCGGGCGAGGCGGGCGCGGCGCGCGCGCGGGGCCGCTGCGTCGCGCGCGCGTTCGACCGGCGCGTCGCGCGCGCGCTCCGGCTCATGCAGGAGAGGCCGGCGGAGCGCTGGACCCTCGAGGCGCTCGCGAAGGCGGCGGGCCTCTCCCGCGCCGCGCTGGCGCGGCGGTTCCTGGCCGAGCTGGGGGTCCCGCCGCTCCGCTACCTCGCCGAGCTGCGGATGCAGCGGGCGGCCGAGCTGCTCGCCGAGGGCGACGGCTCGCTGGCGTCGGTCGCGGCCGAGGTCGGCTACGACTCGGAGTTCGCGTTCAGCCGCGCATTCAAGCGGCACACGGGCGAGGCGCCGGGCGCGTTCCGCCGGCGCAGCCGCTCCGAGGGGGCAGCGTTCCGGCTGCCGCCGGTGCGCGCGGCGGCGTGAGGGCCTCGCCGGGGCGGAGCGGGAGCCGTTGCCGACGTGGCGCGCGACCGAGGGCGGCGCGCTTGGGGCGGGATCCTGACCGGCGTCACTCGCGGAGCGGGTCGAAGCACTTCTCCGGGCGGGTCGGCGCGCCGTCGCGCACCGCCTTCTCGTGCGCCTGAAAGCAGCGGAGGCGGGCCTCGATGAGCGGATTCTCCACTCCCTCCGGCAGCAGGTCGCGTGCGCGCGACGCTGCGGTGATGGCCTCCGTAACTCGACCTTGCAGGAGGAGCAGCATGCCGTAGGTGTCGTAGCAGCGTACGCAGCTCGGGTCCGTCTTGAGGGCGCGCTGCACGAACGCCTGCGCTTCGTCGAGATCCCGGAGCTGGATGCGGTATCGGGCGACGAAAGTGAGCTGTTCGGCGGTGGCGGCAGTGCGGCTCAGGCGGTCGATGAGCGGAGCGGTGCGTACGATTGCCTGGAGCGGCGTGATGATGCGACGGCTCGACATCGCGCGAATCAGTTTTGCCATCGCCAGGAGATACCGAGGATCCGTCGGCTTCGCCGCGAGCGCCGCCGTGAGCTCCTGCTCCGCCTCCCTGAGGCGGGACTCGGCGGTCCGGAAGAGCCCGCGCCAGAAGCGCACGTCGGGGTTGTTCGGCTCATGCGCGACCGCCTCGTCGAGCTGCGCCGCCGCCCATGCCCTCCCATCGCCCTGCCACCGCCTCAAACGGGCCCAGAGCACGTGCACCTCGGCGTCGCTCATCGCCCGCTCGACCAGCGGCGGCGGGGGCGGCGGGGCCGTGTAGGGGCCGATCTTCCTGATGGGCCGCGTTCCGACGAGGTAGCTCCGGTAATCCCGCTCGAGCTGCTCGGGCGAGATATCGCCGAACGCATCTTGGAAGGCCTGCCGCACCGGAGCGCCCCGCGAAGCCGCTTCGAGGAAGCTGGCAAAGCGCTGCACGTACGGATCGGGGCCGTTGAGCAGCATGTGAACGAGCCCCCAAGAGCTCAGGTCGTTGAGCGCCACCCGGCGCCGCTCGGCCTCCGACGGATCGTCGGCGAGACTGTAGAAGTCCTCTCGCCTGGCACGGATGAGCTCCGCGGCGGACGCCGCCTCGCTGGCGGGGACCAGCTGGAGCGTGAACGCGCCATTGCGCACGGTGCGCCCGGAGGCCCCCTTCAGGAAGTCGTGATAGGGCAGCGCTGAGCCCACGTATGCATAACCACCCCGCACGCGAAACGTCGAGTAAAACTGGGCGAGGCCCTGTTTGAGCCACGGCGGCGCGGGCCCGATGCTCTGCGCGATGAAGTGGTACGCGAGCCCGCGCTGGAACGTGATGCGCGCCGGCTCCCCGAGCGAGCCATACATGACCATCGTCGGCGCCCGCTCGATGTCGTTTGGCAGCGCGTGAAAGAAGACGCCGCTGGACGGCGCTGGACTGAACCGACGGAAGTCCTGCTCGCGCGCGAACAGGACGATCTGCATGCGAAACGGCTCCGGAGCATCGCTCGGGAAGCAGACGTCTTCGAGGGCATTGTACGATCTCTCGAGCTCCGCGAGGACCCCGCGCGCCTCGGAGCGGTCGAGATCTGTCCGCAACACGACGTGCTGCGAGGAGAGCTCTACCCACGGGGCGCCGCCCTGGGACGCGCAGGTGAGAGGTGGCTTCGGCGGAGCACAACCGAGCCCGCTGGCGGCGCAGAGCGCGAGCGCGGCAGCGCTGAGGGACCGCGCGATGAACGAAGTCGACATGCGATTTCCCCGATGCCCGTCGCCGTGAGGGCGCGAGCTGTGGCGGGGCGTACACCAGCGCCGCGCATGCGTCCAGGTGTCATCGACCCAAGGCTTGCCTGCAGGCAGAGCTCACCGGAACGCAGACCTCATTCCGGTGAGCATCGACGGATTACCACATCACGTAGGGAGCTCGCGCCAGGCGCATCATCATTGCGGAACGTGCATATCGCGTCTACAATACCGAGCCGTGCGTAACCGTTCAGCGCAGTAAAGTTTGCGCCCAACTGAACAGGGCTAGTCAACAGCCGATTGGATGCTCACTCCCCGTGACACCGGATCGAAGCCGTCAGGCCACCGTGTGAGCGTGTCCGCTCTCGCCCCTGCGAGTTCGGCTCGCTCAAGCCCCTCGCAACGAAGGTCGGCTCCGAGAAGGATCGCTCTGGCGAAAGTTGCCCCCTCGACCTTTGCACCGCGAAGGTCCGCGCCGGAGAAATCAGCTTCTTCGAACCCTCCGCTCCGCATCATCGCATCTCTTAGGTCCGCCCTAACAAAGCTTGCACGTGAGGCGTTGCATGCTGCGAGCCTCGCTCGCGTGAGCTTCGCATTCTCGAGGCAGGCATCTTCCAGCCATGCCGATCGCAGCTCAGATTCCGACAGATCGGCACCTCGGAGAACCTGTCCCTCGAGAAGCGCTCGATGGAGATTCATCCGGGATAGATTGATTCCTACGAGGCTGTCGGCGTCTACCTTCACGTCGTCACCTGTCTCGCAACGGATCACAATCATCACCAACTCTCCGGGTTGATTGGAAGATTCTCCCAAGGAACAAGGCGTTCCGGACGCCCTCCTGCCCATGGCTGTATCGCCGGTTCCTGCCCGAACACCCTACCGGCGATGTACCGGTGGTTGCCGTCCACGATCATCCTGCCATCAACCTTGATGGCCGGCGCGACCTCCCTGGCGATCAATTTGTCTACATATTGCTGAACTAGCGGCAAGGACACGCCTCGCGCTTGCTGCGATGCCAGAGGAGCGTCTTTCATCGCTTCTCGGATCACCTGCTCGGTGACCTGAGATCCACTCGTGATGGTGGCTCTTCCTCCCGTTGCCACCTCCGGTACGACCGCCCCACCCCCCAGCTTCGGCAGCACGGCGCCGAGCACCATCGCCGGCCCGATGCCGCTCTCGACGGCGACCGTGACGCCCAGCGCCGCGACATCCATCGCCGCCCGGAGGTCCTGCATGAACGCCTCCGCGTCGTTGCCCGCGTGCCACGCCAGCGCCCCGAGCTCGAGCGCCTCGTGGAAGTCCCGCGCCACGGCCGCCGACCAGCTGAAACTCGGCAAGATGACCAGGTCCCCCATCACCGACCCGCTCACCAGCCCGGGCGTCGACTTCTCGCCGGTCAGGTCCGACAGCCGCACCCCGCGCTCCAGCACCGCCGCCAGCGTCTCCCCGGCGCCCGAGTACTCGTCGCCCACCGACGAGCCGCCGCGCTGCTCGAAGTACTCGTCTCCGGCATGGATGAACGACGCCCAGTCGCTCTCGAACTCCGGATTCCCTCGCTCCTCCGCCCCACCGGGAGGCTGTGGCGGCCCCACCTCGCCGGATGGCGGCGTAGGCGCACCAGGCGCCGTGACGACTTCTTCCGTGGCGTCCCAGATCCCCTTCAGCTCTCCGGTGGTGTCGTCATACTCGGCGTATCCCCAACCGCCGTTGTCGAACGACACCCGCTCCCAGTAGAACCCCGTCGGATCCACGAGGTTCACCGGGTCGTTCATCACATAGCTGTACCGGTTGTAGCTCTGCCCCCACAGCGGGTCGGTCACCAGCGGATCCGGCGTCAAGAACCGCCGCAGGCTCGGGTCGTACACCCGCCCGCGCATGTCGATCAGCCCCAGCTCATCGTCGTGCCGGTGCCCCGTGAACCCGTGCTTCACCTCGCTCTTCGCCACCCCCGGCGCCTTGCCGTCGGCGTCGATCCGCCTCCCGAACGGCTCGTAGTGCAGCCGCTCCACCTCCTCGCCCGCCTCGTCCGTCAACAGCCCCACGCTCCCCAGCGGGTCCGCGTGCACGTACAGCGTCTGCTCCTTCCTAGGACCCGCGAACACCACCTGCGCCACCTCCCCCTCGGGCGACGCCACCCGGAACACGTGCCGTGTCCCGCCCGCGTCCGTGCGCCGCTCGTACACGCCGCCCACGTAGACCGTCTCCTCCCCCTCGTGCTTCTTCTTCACCCGCGCACCGAACGCGTCGTACAGAAACGCCCAGCTCTTTCCCTCCTTCTCCACCCGCCTCGGCAGGTCGAACGCCGTGTACGCGATCCACAACCCCGCGCTCGACCTCTCCAGCCGCCCCGCCGCGTCGTGGCTGAACGTCACCGCATCGCGCCCCGCCACGATCCGCGGCCTTCCCCCCGGCTCGTACCGGTTCTCCTCCGCCACCACCCCGTCGACCGCGACCGTGCGCAGGTTGCCGAGCTCGTCGTAACCGTACGTCGTCCCCCGCGCCCCGCCCGGCGCCGCGAGCTCCCACCGCTCCAGCCGGCCCGCCTCGTCGTACCCGAACGTCTCCACCCGCAGCGCCACCCCGTCGCGCCGCTCCCGCACCCGACCATCGTCGTGATAGCCGTACGTCAGCGCCTGCAGCGACGCGTTCGTCTTCGCCTCCACCGTCGCCAGCCGACCTGTCATCGGCTCGTACGTCCGCTCCGCGCGCACCCCGTTGCCGAACGTCGCTTCCAGCAGCGCCCCGTCCGCGTTCCGCGCGTTCACCTTCCAGAGCGACCGCGTCGTCCCGTCCTCCTGGCTCGCGCGCAGCTCCGACAGCGACCCGTCCTCGTACACGTGCTTCACACGGAACCGATCCCGCCCCGGCACCTTCGGATACAAGAGCTCATCGCGCAGCCCGTCGGGCGTGTACGTCACCCCCACCGAGAACGCCTCGCCCTCGATCGCCGTCCACACCTCCGAGACGCGCCCCTGCGCGTCGTACGTAGTGAGCACCTCCGTCCCATCCGGGCTCAGCGCCGACGCAAGCTGCCCCACCCCGTGCTCCGCCTTGTCCCACGTGAACGTCGTCGCCCCGTCGGCGCTCGTCACCACGCGCCTTCGCCCCATCGCGTCCCGCTCCACCACCGTCCTCTGCCCCAGCGCGTTCACCTCCTCCCGCGTCTCCCCAAACCCGTTGTACCGCGTCCGCCGCACCCCGGCGTCCGGGTCGCGCACCTCGATGCGCCGACCGCGGATGTCGTACGCCATCTCCGTCGTGTTCCCCTTCGGGTCGATCACCTTCCAGAGCTTGCCGTGCAGGCCATACGCGAACTGCGTCGGCTGCCACGCCCCGTCCACCTCCACCGCCGTCTCGCTCGGCCGCCCCTCCACGTCCACGATCGTCCGGCTCCGCCGCCCTTCCGGATCGATCCCGATCGTCTGCAACAGCTCGTGCTCGTACCACTGCTGCGTCCCGTCCGGCCCCGTCTCCGACAGCACGCGGCCCAGGCTGTCGTACGTCCGCTCGGCCCGCTCCTCCGCCGCCACGTCGAACCCTGGCCGGCTCGCCGACAGCGGCCGGCCGAAGACGTCATACGACCTCCCGCGCACCTTCATCCGCCCGTCGAACGCTCGCTCCGCCTCTTTCACCGCGAGGCCACGCTCGTCCAGCGTCACGACCGCGCTGCCGCCGCTCGCCAGCGTCGTCTCCACCACGAGTCCCGCCGTCTCGCCCGCCTCCACCCAGGCGGCCATCGTCGTCTCGCTCGACGCGCCGGCGCCGGACCTCGCCTGCTTCAGCCGCCCGAGGTCGTCGTGCACCCGCGTCGACCACGCGCCGTTCGCGTCGATCTCGCCCATCAGCACGCCATACGCCGGGTGCGTGTACGTCCAGTGCGACACCCCGAGCCCGTTCCACACCTGGCTGACGAAGATCCCTTCGCCCGACACATCGTCGTGCGCGTAGCTCCAGATCCGCGGCGACTCCCCGGCCGCTTCGCGCTTCTCCTCGATGAGCCGCCCGGCCTCGTCGAGCTGGAACGAGATCGTCTCCCGGACGTCGGGATCGGTGCTGTCCGGCTCGATCTTCACCTCGTCGAGCAGCCCGCGCTCGTCGTGGTGGTAGTCGACATGCAGCTTCCCCGGCACGGTCGCGCCGGCCTCGTACACGCGCTCCGTGTGTGTATCGATCAGCCCGACGAGCCACTCGTCGGGCCGCACGTCGAACGTCCTCGTCACCTCGCGGCGCACGCCCCGCGCCGTCTCGACGATCGATCTCCGCACGTTGCCGTGATCATCCACCTCGTACGTCGCGCTCTGCCGGATCGGCGCGGCATCCCCCGGATCGTCCACGTCCGGGCAGTGCAGGCGCACCCCCTCGGCCCAGTCGATGTCCACCTCGGGATCCTCGTACTCGCGCCGCAACGTCCCCTGCACCGAGACGAGGTAGCTGCGACCCTCGTTGAGCCCGACGACCCGGTAGTCGATCTCCTGCTCGACCACCCGCGCCCTCGCGCTCGCGGGGCCCTCCTCGATCGTGCACGATCCGTCGGTCAGCGGGTCGCAGTCGCGCGCGCCCAGCGGGCCGTGGGGCACGATCGGCGTGACCTCCCGGATCCACCGCGGCCGACCCGCGAACGGATACGCCGTCCCCACGCGCGTCTCGTTGTCGAACGCCGTGATCCGCTCCACGGGCCACGCGCCGCTCCACTCGATCATCCGCTCGAATCCGAGCGAGCCGCGCCCGAGCAGGTCCGCCCGCGGGTCCTCGAACCGGTAGCTCGTCCCGCCGGGCCGCTCCAGCCCGCCCACCCAGGCCACCACCGGCGCCCCACGGTACACGCACCGCAGCGGATACGTACACACGTCCCGAGGCGACGATGAAGGGTTCGTCCGGCCATACCGGACGTGCGCGCGGTAGGCCCTCGGCTCGTCGCCGTCGGACACGCCGCTCAGGAGCTCCACATCCTTTCCGATCGCGCGCGTGACCTCGAGGACGTTCGCTCGCCGCGTGAGCACGTCGGCGCGGCCATCCGCGTCGAAGTCGCCGTGCCACATCGCGCCCCCCGCAGGGAGCGGCGAATAGTGTGTCCCCGTCTCCGGCTCCTCCCAGCCGATCTCCTGGCGCAGGAACGTGCCGTCGCCGCGCGAGAGGAAGGCGAGGATCAGGTCCGTGAAGCGGCCCGCGGGCGGCACGGGGTTGAGCCAGTCGGAGATCGACACGAGGAGATCGTCGCGCCCGTCGCGGTTCAGGTCGAACGGCTCGACCACGAGGCCTCCTGCCTCCAGCGCCAGCGCCTCCGCGACCCCGGGATCCGGGAGCGTCACGACAGGCCGGAGCCCGTTGCCCGTGTTCATGCTGAGCCACACCGAGCCCGCGTCCACGTCGACCCAGAGCGCGTCGCTCAGCCCGTCGCCGTTGATGTCGGCGAGCGTCGCCGGCACGCCCCCGCGCTTCAGCGGAAACGCGGGCCCGGTCGTCACTTCCCCGGCGTCGTCGAGCCCGATCGCCACCCCCGCCTCGCAGCTCTCGTCCTCGCCGACGATCAGCTCGCCGCGACCGTCGCCGTCGAGATCGCCGCCAACCGCCTCACACGGCCTGGGCGCGGCGCGTACGCCGGTCACGATGCGGTCGCCGAACCGGCCGCCCTCGTTCATCAGGATGCTCCAGGACGATTCGTCGACCGACTGCGCGAACTCGACGAGCACATCGAGCAACGCATCGCCGTTCAGGTCGACCAGCTCGAGCGCGGGCGCGGACGCGGAGAACTTGCCCGAGCAGACGCGCGCCTTGCCCCCCGAAATCGTGGCGCCCGTGGCGACGAACGCTTCGCTCTCATCGCTCCAAGCGACCAGCCTGTAGCGACATGCCCCGGTGTCGTAGGCGAGCAGGTCCACCTTGCCGTCCCCGTCGGCGTCCACGGGACGGCTGTGCTTCAGGTTGACCTCCTCGAGCGGAGAGCCCGCCGGGTTGACGTGCAGGGTCCGGAACGAGACCTCGCTGCCGGGCTCGGAGAGGCTCAGGAACAGCTGATCCGGCGGCTCCGGCGGGACGGGGGGATGGGGGTGCCCCGGCAGCGGGGGCGGGGACCACGGCGTCGGCACGTCAACCGCGTGGAGGATGTCGTCCCTCCCATCCCCGTTGGCGTCGAACACGCGCACCGAGGTGATATCCCCGGAGATGGGAAGCACCGGACCGCCGGCGAACAGCAAAGGATCCTCGTGGATCCAGTGCAGCCGCTTCGGCCAGAGGCAGGTCCCCTGATGTCCGCACTTCTGCACCGAGGAGAGCAGGCTCCGGCCGAGCTGCCCCATCTCGTAGTCGAGCGTGTACTCCCAGACCTTCTGCGTGGACACCGGGTTCGGGGCCCACATCGCGATCGTCTTGAGCCGCTTCGTCGATCGCCACCCGATCCCGCCCCCGTAGGAGATGCTCGGGTCGGGGCGATCCTCGTACTCGAACACGATCTTCCGGCGCGGAGATGACCCCGGCCCGTAGGCGATCGTCTCGATCAGGAACTCGTGCGAGTAGGGTGGCTTGGTGGACCCGTGCTTCTCGTAGAGGTACTCGATCTCGTTCCCCGAGCGATCGCGCTCGCGCGCGAGCAGCCAGAGCGGCCTCACCACGCCCGCCGGCTCCTCGACCTTGCCGCGGGTCACGACGCGCGTGGCGTAGGTCTCCTCGTAGATGCGGATCCTACCGTCCTTGGTGCGCACCTCGAAGGCCCCCGGCCCGCTCCGGCTCGACCCGCCGAGCGCGCGGATCATCGACATCTCGTCGTCCTCGGTGCGGTATTCGGCTCGACCATCGAACCCCTTCACCGCGACGAGCTTCTTGCCGTCGAGGCAATAGCGGTCGGTCGCGTCGTAGTCCGGGCCGTCGGCGTGCCCCTCCGTGGCGATCGTCGTGTCGCAACGCGCGATCGCCGACGAGCTGCCGGCGACGCTCCACCCGCGTCCCACCGGACCGTTGCCGCCACGGCTCGAATAGCGGAGCGCGAGCTCCGGCGTCACCCCGAGCCCCGGCGGGACGTCGAGCGGAATCGTATAAATGTAGGCTCCGTCCGCGGTGACTTGCCCCGCGCCGGGCAGGTATCCGACCTCGTCGCCGCTGAGGATCGGGGACTGCGGGAGGTCCAGGGGCTCTGGCAGCGTGGGCCGCTCACCGCCCGTCGACGCGGAGGCGGCCAGGCCGAGCCGCTCGGCCGCCGGCCGCTCGTGCGTGCCGCAGGCGACGAGGGCGAGCACGAGAAGGGATAGAAACCAGCCTAGAGACGACGCCCGTGAGGACGCCGCCATCGATGCATGCACCGAGGACCGCCGAGGACGCTGCGAGGCCGCCTGCGCAGCCTCGCGCCGAGGTTCATTCTTCATATCGTCCACCTGTGGAGCGGGGCTTCCCCCCGACACACTCCCGCCGACTCAGGTTCAATCCGCTGCCATGAAGAGCAGCTCGCCGGGGAGCATGGCAAACACCATGGTCATGATGGCGAGTCAATCCGGTTCTTGGGCTCGACTCTCCGTCGAGATCGATCCCGGTCTCCCGGCGAGACCTCACCCTTCCTGCGAGACCACCTCCGGTCTCGGCGCGAAGGGTCCCGTCTCCCTCCGCGACCACCTCCCCTCTCCCGGCGAGACCCTGCTCTCCCTCCGCGACCACCTCAGGTCTCGGGGAGAGGGGTTTCGTCTTTTTCCGCGACCGCCTCCCCTCTCCCGGCGAGACCCTACCCTCCCTTCGAGGTCGCTCCCCGGATTGCCTTCATAGTGGAACCTTCTTCCCCCGCCTATCCTCCCCACCGTCGAAAACATGCCTCCTCCCTCCCGGGCGCGGATTCCCAATGACACACACGCGCGCCGTGCATAGGTTGCGACAATGGCCATGACCAAGACCCGATCGACATCGAAGAACTCCAAGCCGTCTGTGTCAGCACGCCAGATCTTCACCACCTCGGACGCGAACGAGGCCTATCGCCACTTCCTGCCGCGGGTGCAGGCGGAGGTCCCGGCCGAGCGCGCCGAGGTCTGCCGGCTCTCGATCGAGCTCGTCCGCGCCAACGTGGACCGCGGCGTCCAGGCGGTGCTCCCTCATCTCGGCCGCGTCCGGGAGAAGCTGCCGCTCTGCCCGATCGACGACGTGCTCGAGCTCCCGAGCCTCGCGCTCGGGCTCGTCGCGGCCGCGGGGCGCGTCGCGACGGCCGCGAGCGAGCGCGAGATCGAGGCGCGCCTCGAGAAATTCCGCCCGATGCGCGATCTCACGCTACGGCAACTCGAGATCTTCGCGGATCTGAAGCTCGTCCCCAAGCAACGCGTCGCCGCGATCCGGCGCGGATCGGGGCCGGTCGACAGCGCCCGCGACGGTGTCGATATCGCCGGGATGTTCGACGAGCTCGCGGACGCGCTCGACGGCAAACACCCGTTCTCGCGCGACTACCTCGCCGAGATGGCCGAGCACGCGAGCTGGCTCCTCGTCCAGCTCAAGCCTCGGGGCGCCCAGCAGAAGCCCTCCGAGCGCTCGCCGGAGGCCATCGTCCGCGATCAGTTCTGGACCGTCATCCACCAGCGCTACGAGCACCTGCGGGAGGCCGGCGTCGCCGTGTTCGGGTTGCGCCAGCTCGACGCCCACGTGCCCCCGATCGGCGCCCGCACCCCGGCGCCCTCGACCGCGCAGACGAGCGGGACGGCGAAGCCGGGCAGCGCCGGGCCCGTCCCGCCCGCCGCAGCGCCGGACCCCACCGCGGAGCCCTGACGCGCGCCGCGCCGCGCGCCCCCCACGCGCGCCGCGCCCCGCGCCCCCCCACGCGCGCTGCGCCTCACCGCCCCTCCACGCAGCCCCCCGGCCGGCCGCGCGCCCGCCTAGTTCCGCGGATCAGAACTCCCGCCAGGGTTCTGCCTCACGAGCGATAGAGAAATAAACGCAAAGGCGCAAAGGCGCAAAACTACAAGTCTTTTTTTTGCGTCTTTGCGTCTTTGCGTCTTTGCGTTGAACTCTCGCTCCGGATCCCTGGCCGGACTTCTGGCAGACGGAACTAGCGCGCCGCGCTCCCGCCCTACCGCTCGGAGGCCTTCCCCTTCGCGCCGGGCGCGGCCGTCCCCGCCCCGCCCTCCCCGGGGAGGCACATCTTCCGCCCCGCGCTGTCGGCGATCTCCTCGCACGTCTTCAGACCCGCCGGGCAATCGCCGGCGCTCTCGCAGTACGCCGAGCAGTGCCCCGGCTGATCCAGGGCGCCGGCCCGGTGCAGGCATCGCCCGTGCTGGCACTCGACCGCCGTCATGCACGCCTCGCCGGGCGCCCGGCCCTGCGGCTTGCTGCACACGCCGTCAGGACCGTCGTCGCGGGAGCGGCACACGTACCCCGCGCCGCACTCCCGGTCGACCCGGCAGCCCTTCGAGCAGACGCCCCCGATCGCCGCGCACACCGACGACGCGCACTCCGCGCCGTCCGCGCACGCCTCGCCGAACCCCTTCTTCGCCGCCGGGCTCACCCCCGCGCGCTCCTCGCAGCCCGCCCCCGCGCCGAGCGCTCCCATCACCCCGGCGAGCGCCAGCACCCAGCCGCGCGCCAGCACCCACCCGCGCGCCAGCACCCACCCGCGCGCCAGCGCCCCGCCGCGCGCCAGCGCCCCGCCGCCCCCCGCTCCGCCTCGCATCGCCCGCCCTCCGTGGATCATCCGCCGACCTCCCGAGGCTCCGACGGGCGACGCTCCCCTGGCGCACCAGGTCGCCGGGCCGCCTGCGCTCCTAGCACACCGGCGGCCTGGTGCGATCGCCAACCTCCCGACCCACGGAACCTCACCCGAGCACGTCGCGCAGCCCACCAGCTTGGGCCAGATCCGTCTAAAGTGCGCCGCCATGTCCAACCCGATCGACGTCGATCCCAACCGCCAGAGAGAAACCCCCGCCCAGCGAGAGCCCTCCCAGCGAGACACCCCCGCGGCTTTTTTCCGCGGAAACACGGCGCCCGACGCGCGCACCGGCATGCACCCGGTCGCCCTCCGCCGCGCCTTCGCGGACCACCTCCACTACTCGCGCGCCCGGGAATCCCTGTCCGCCACGCCGTTCGACCGGTACGTCGCCCTCGCCCTCTCCGTGCGCGATCGCCTCGTCGACCGGTGGACCAAGACCCAGCACACCTACTACGAGCAGGACGTCAAGCGCGGCTACTACCTCTCCGCCGAGTTCCTCCTCGGCCGCGCGCTCGTCAACAACCTGCAGGCCCTCGACATCTACGACAGCTACAAGACCGTCCTCGCCGAGCTCGGCCTCAACCTCGACGACCTCGTCGAGCAGGAGCCCGACGCCGGGCTCGGCAACGGCGGCCTCGGCCGGCTCGCCGCCTGCTTCCTCGACTCCATGGCCACCATCGGCCTGCCCACCTACGGCTACGGCATCCGCTACGAGTTCGGCATCTTCGAGCAGGCCATCCGCGACGGCTACCAGGTCGAGCGCGCCGACGAGTGGCTCCGCTTCGGCAACCCCTGGGAGGTCGAGCGCCCCGAGCACGCCGTCCCGGTCTCGTTCGGCGGCTACACCGAGCGCGTCCCCGACAAGCGCGGCGGCTTCCGCGTCATCTGGCGCCCCGCCGAGCAGGTCGTCGGCGTCCCCTTCGACACGCCCATCGCCGGCTTCCAGTCGAACACCGTGAACACCCTCCGGCTGTGGTCCGCCCGCGCCGGCGAGGAGTTCGACTTCGAGCTCTTCAACGCAGGCGACTACGTGCACGCCGTCCACGAGAAGAACCAGTCGGAGGTCATCTCCAAGGTCCTCTACCCGAACGACAACTTCGACAAGGGCAAGGAGCTGCGCCTCCGCCAGGAGTACTTCTTCGTCGCCTGCTCCATCGCCGACATCGTGAACCGCTACAACCGGGTCCACCCGGACTTCTCGCGCTTCGCCGAGAAGAACGCGATCCAGCTGAACGACACGCACCCCGCCATCGCCATCGCCGAGCTGATGCGCGTGCTCATCGACGAGCACCTCGTCACCTGGGAGGACGCGTGGAAGCAGACCGTCGCCTCGTTCGGGTACACGAACCACACGCTCCTCCCCGAGGCGCTCGAGCGCTGGCCCGTCGCGCTCTTCGAGCGGCTCCTGCCGAGGCACCTCGAGATCATCTACGAGATCAACCGGCGCTTCCTGCGCGAGGTCATGGACGCCCACCCGCAGGACCACGACCGCGTCGCGCGGATGTCGCTCATCGAGGAGGGGCACGAGCGCCACGTGCGCATGGCCTACCTCGCCGTCGTCGGCTCGCACTCGGTGAACGGCGTGGCCAAGCTCCACTCCGAGCTCGTCAAGCGCGACCTGCTCCGCGACTTCTACGACCTCTGGCCCGAGCGGTTCAACAACAAGACGAACGGCGTCACGTTCCGGCGGTGGCTGCTCGCCTGCAACCCCGCGCTCGCCGCGCTCGTCACCGAGAAGGTCGGCCCGCGCTGGGTGACGGAGTTCGAGCGGCTGCGCGAGCTCGAGCGCCACCTCGACGACCCGGAGTTCATCGAGCGGATCGCCAGCGTCAAGCGCGCGAACAAGGCGGCGCTCGCCAAGTTCATCGGGCAGGAGCTCGACATCTCCGTCGACCCCGCCTCGATCTTCGACGTCCAGATCAAGCGCCTCCACGAGTACAAGCGCCAGCTGCTCAACGCGCTCCACATCGTCGCGCTCTACCTGCGCCAGAAGCGCGGCGAGCACGTCACGCCGCGGACCTTCATCTTCGGCGCCAAGGCGGCCCCCGGCTACCGGCAGGCGAAGCTCATCATCAAGTTCATCCACGCCGTCGCCTACGTCGTGAACGGCGACCGGCGCCAGAGCGCGCTCCGCGTCGTGTTCATGCCGAACTACCGCGTCTCGCTGGCCGAGCGCATCATCCCGGCCGCCGACGTCTCCGAGCAGATCTCGACCGCCGGCATGGAGGCGTCGGGCACCGGCAACATGAAGCTCGCGCTGAACGGCGCGCTCACCGTCGGCACGCTCGACGGCGCGAACATCGAGATCCGCGACGCCGTGGGCCCGGAGAACTTCTTCCTGTTCGGCCTCACCGCCGACGAGGTGATCGCCCGCCGCTGCGAGCACTTCGAGGGGCGCGACGCGGTCGCGGCCGACCCGGAGCTCCGCGAGGTGGTCGACCTCATCTCGTCGGGCTTCTTCTCGCCGGAGTACCGCGAGCTCTTCCAGCCCCTGCTCGACCGGCTGCTCGGCCGCGACGAGTACATGATGCTCGCCGACTTCAAGGCCTACTCCGCCTGCCAGCGCGAGGTGGAGGCGGCCTACGCCGACCGGAAGAGCTGGCTGCGCAAGTCCGCGCTCAACATCGCCCGCGTGGGCGAGTTCTCCTCCGACCGCACGGTGCGCGAGTACGCGCGCGACATCTGGGGCCTCACGCCCGTCGAGATCGACGTCGGCGCCGCCAAGTCGCTCCTGTGACCGCGTGACCCCGCCGCCCCGGCAGGCGCGCCCGCGCCCGCCGGGCGACGGCGACGCGCGCTCGCCCGCGGCGGTGCCGCACCGGGCGGACCCGACGGGCGCCCCCGGGCAGGCCCGACCCCTCTTCAGCTCGCTTCCAGGACGCGGACGCCGCGACGGACGGAAAAATCCCGGTGCGCGCGTGGCGGACCACGCCCCGCCGGAGCATGCTTCCGAAGCGTGAGCTTCCTCCGTCGGCCGCTCGCCGGGGCGGGGCTCTTGCTATCCTTCCCGACGGATTTATGCCGAACGATCCTGAGGAGAGAGAAGACAGGCAGGGCGACCTCGCGACGGAGCGGGAACGGAAGGTCGAGAAGGCCCGCCGCTACAAGGTCGTGTTCCACAACGACGACTACACGACGATGGAGTTCGTCGTCCTTGTCCTGATGAAGTTCTTCCACCGCACCGAGACGGAGGCCACGCACATCATGCTGAGCGTGCACCACCGCGGCCACGGGGTCGCGGGCGTGTACACCAAGGATGTCGCGGAGACCAAGGTCGCCCAAGTCCAGGACTTCGCCAAGGAGCACGGAATGCCCCTTCGGTTGACCGCCGAGCCGGAATGACCATGCGCATCAGCCCCGAAGTTGAGATCGCCTTTTCGCTCGCCACCCGGGAGGCCTCGCGCCGCCGGCACGAGTTCGTGACCATCGAGCACCTGCTCTACGCGCTGCTCTTCGACGAGGAGACGGCCGAGGTCCTCCGGCACGCCGGGGGCGACACCCCGCTCTTGAAGAAGAAGCTGGAGCGCTTCCTCGACGAGGAGATCGAGGCGCTGCCGGACGACGCGGACACGAGCCCGACGCTCTCGCTCGGGTTCCAGCGCGTGGTCGGCCGCGCCGCCATGCACGTGCAGTCCTCGGGCAAGAAGGAGCTCAAGGGGGCGAACGTGCTGGTCGCGATGTTCGCCGAGCGCGACTGCCCGGCCGTGACCCTCCTCGGGGAGCAGGGCATCAGCCGCTTCGACGTCGTGAACTACATCTCCCACGGCATCTCGAAGACGGGCCAGGACGACAGCCTCCGCGAGGAGTCGTCGTCCGACGAGGGCGGCGAGCCCGGCGGCGCGCAGCCGGTCAAGGATCCGCTCGCCGCGTTCACGATGAACCTCAACAAGGAGGCGGCCGAGGGGCGCATCGACCCGCTGGTCGGCCGCGAGAACGAGGTCGCCCGGACGATCCAGGTGCTCGCGCGGCGGCGCAAGAACAACCCGCTGCTCATCGGCGACGCCGGGGTCGGCAAGACCGCGATCGTGGAGGGGCTGGCGCAGCGGATCGAGAAGAACGACGTGCCCGCGCCGCTCAAGGACGCGACCGTCTACGCGCTCGACATGGGCGCGCTCCTCGCCGGCACGAAGTACCGCGGCGACTTCGAGAACCGCCTCAAGGCGGTGCTGCGCGCGCTGGAGAAGCAGCCGGGCTCGGTCCTGTTCATCGACGAGATCCACACGATCATCGGCGCGGGGGCCGCGAGCGGCGGGACGATGGACGCCTCGAACCTGCTCAAGCCCGCGCTGGCGTCGGGCCGGCTGCGCTGCATCGGCGCGACCACGTTCCAGGAGTACCGCGGCCACCTCGAGCGCGACAGCGCGCTCGCGCGGCGGTTCCAGCGCATCGAGGTGACCGAGCCGTCGGTCGACGACACGACGCAGATCCTGAAGGGCCTGCAGAAGCGCTACGAGGAGTTCCACAAGATCACGTACACGCCCGAGGCGCTCGACGCCGCGGCGAAGCTGTCGGCGCGCTACCTCCAGGACCGCCGGCTGCCCGACAAGGCGATCGACCTGCTCGACGAGGCGGGCGCGGCGGCGCGGCTGAAGCACGGCGACGGGTACACGGTCGACACCGCGGACATCGAGCTCGTCATCGCGAAGATGGCGCAGATCCCGCCGCGGCAGGTGTCGACGTCGGACAAGGCGCAGCTCAAGGATCTCGAGCAGTCGCTGCGCTCGGTGATCTTCGGCCAGGACGAGGCGGTGAAGCAGCTCTCGTCCGCGATCAAGCTGTCGCGCGCCGGGCTGCGCGCGCCGGAGAAGCCGATCGGCTCGTTCCTGTTCTCGGGCCCGACCGGCGTCGGCAAGACCGAGCTCGCGAAGCAGCTCGCCAAGGCGCTCGGCATCGGCTTTTTGCGGTTCGACATGAGCGAGTACCAGGAGCGGCACACGGTCTCGCGGCTCATCGGCGCGCCGCCCGGCTACGTCGGGTTCGATCGCGGCGGCCTGCTGACCGAGGCGGCGGCGAAGACGCCGCACGCGGTGCTCTTGCTCGACGAGATCGAGAAGGCGCACCCGGACGTGTTCCAGGTGCTGCTCCAGGTGATGGATCACGGCACGCTGACCGACAACAACGGCAAGAAGAGCGACTTCCGCCACATGGTGCTGATCATGACGAGCAACGTGGGCGCGCGGGAGCTCGCGCAGGCGCGGGTCGGCTTCGGCGAGCGGGGGTCGGCGGGCGACGACGACAAGGCGTACAAGAACACGTTCAGCCCGGAGTTCAGGAACCGGCTGGACGCGCGCATCATGTTCCGGTCGCTGGATCCGTCGGTGATGGGGAGCATCGTCGACAAGTTCATCGGCGAGCTCGCGGCGATGCTCGCGGACCGGTCGGTCACCATCGACGTGACCGAGCGGGCGAGGGCGGAGCTCTCGACGCGCGGGTACGATCCGGCGAACGGGGCGCGGCCGCTCGGGCGCGTCATCGAGAACGAGATCAAGCGGCGGCTCGGGGACGAGCTGCTCTTCGGGGCCCTCGAGAACGGGGGGAACGTCACCGTCGACTTCGAGGGGGGCGACTTCACGTTCAAGTTCGCGGCGGCGAACGGGAGCGGGAGCGGGAGCGGGGGGGACGCGGAGAAGGCGAAGGCGAACGGGGCGAAGGTGGAGCCGGCGGCCGTCGGCTAGCACCCCTCTCGGGGTGCAACGGAGCCAGCGGGGAGGGGGTGCCCGTGCGCGCGGGCGGCGGGGGCCCCTCCCGCGAACTCGCGCCTTGTAGAAGGCAATTGCCATGAGTACGGGGAGAGCCGGTCCGGGAGCGACCCGCTTCGATGCGGGCCGGCGCTCGGATTCGCGGGGCCCTACCCCGCCGCCCGCGCGCACGGGCACCCCCTCCCCGCTGGCTCTTCGCGGCTGGCCGGCAGACCGACCCGCGTGCGCTACCTCATCAGGTCGGACGGGCGGCGTTGCGGATCGCTGGCTTGGTGGATCAGTTCAGCGAGTGCGGCATCGCGAGGGTGAAGGGCGCGATCTCGGCGTCGAAGACGCGGCCGTCCGGGCGGTGCATCTGGTAGGTGCCGCGCATCGAGCCGCGCGGGGTCTCGAGCACGCAGCCGCTCGTGTACTCGAAGTGCTCGCCAGGCTTCAGCGAGGGCTGCTGGCCGACCACGCCAGGGCCGCGCACCTCCTCCACCTTCCCGCTGCCGTGCGTGATGATCCAGTGCCTCGTCCTCAGCTGGGCAGGCTCGGCGCCTTCGTTCGCAATCCGCACCGTGTAGGCGAAGACGTAGCGGTGCTCCGTCGGGGATGACTGCGTGGGGACGTACACCGTCGAGACGGTGACCCGGATGCCCTGCGTGATGGCCGTCGACACAACCACGCACTGCCACCGCTGCGCCGCGCGCACAAGGGCCCGGTCCCGCAAGAGGCACCAGGACAACACCAGGACAACGCCAGGAGAGCGCCAGGAGACCGGCAGGGGACGCCGGGACGGAGACGGCCGGGCTCCCCGAGAGGCGGCGTTGACAGCCTCCAGGCTCATCCGCAGGTTTCGTCGAACCTGGGGTCAACGAGCCGTGGAGGAACCCGCCGTGGGCGAACATGACTGTACCGGTGCTCGATGTGCTGAAGGCGAACGGTTCGTCCCGATCGCGATCCTGCCGCCGGCGCGCGGCGAGAGGGCGGCGATGGTCCAGAACAGCGATGCCCCTGGAGGCGTGGGAGAAGGGCCCGGGCCCGGGTTCACGGCCATCGGGCCCGTGATGCCGGAACGCAAGGTCCGCGAATGGGCCCTCGTGCTGCAGTCGAGCGAGCTTTGGCACGCCGTGCGGTACACCCCGGCAGGCTGGGTGCTCCTCGTGCGCGACGAGGACTACGACTTCGCCGCGACCTCGATCGATCGGTACGAAGCGGAGAACCGCGACTGGCCCCCGCGCCGCGCGCGCGAGCGCCCGCGCCACCCGCCGTCCATCGCCGCCGGCGTCGCGTTCGCCGCCCTCGCCCTCTTCTTCTTCCTCGTCACCGGCCCCGCGAGCGGCGGCGGGCGGCTGTTCCAGCGCGGCGCCTCGGTCGCCGACCTCGTCGTCGGGCCCGAGCCGTGGCGCGCCATCACCGCGCTCACGCTGCACGCCGACTCGGCCCACGTGATCGGCAACGTCATCTCGGGGACGGTCTTCGCGTCCGCCGTGCAACGCCGCCTCGGGCCCGGCGGCGCCGCGCTCGCCGTGGTCGCCTCGGGCGCGATCGGGAACTTCGCGAACGCGCTCTGGCACCACGGCCTGGGCCACCACCACGCCTCGATCGGCGCCTCCACCGCGGTGTTCGGCGCGATCGGGCTGCTCGCCACCACCCAGCTCATGCTCGACCGCGCCCACGACAAGGACAGCGGCGAGAAGCGGCACCTCCTCCAGCTCGTGGCGCCGCTCGTGGGCGGCCTCTCGCTCCTCGGCGCCCTCGGCGCGAGCCCGCGCGCCGACCTCGGCGCCCACGCCTTCGGCCTGCTCAGCGGCGCCGCGATCGGCCTCGTCGCCGGCCTGTCCCTGCGCAACCGGCCCGCGCCGCGCCGCCCCCTCGTCCAGGTCGCCCTCGGCGCGACCGCGACGGGGCTCGTCCTCGGCGCGTGGCAGCTCGCGCTCCGCGCCTGACGCGCGCGCTCAGCCGACCGGCCAGATCCCCACCGTCCCGCCCACCCAGGTCAGATCGCGGTTCTGATCGACCCCGAGCATCTTCCCGCGCGACAGCCGCGCCAGGTTGAGCGCGAGCGAGAGCTCGGGCTCGCCCGGCGCGCGCAGGAACATCATCCGGACCTCGGCCTTCACCCCGCCCCCGTCCGGCATCAGGAGCGCCGGCTCGTACGCGACCTTCTCCTGGAGCAGCCACCTCGAGCGCTCGCCCTCCGGGATCGCGGCGATGTCCTCGCGCGTGACGTCGACCTTCACCCCCGAGCCCGCGAAGGAGAACAGCGGCTTGAGCACGTAGCGCTCGAGATCCGGCGGCGCCTCGTCGAGCGCGCTGAGGAGCCGCGCCCGCGGGACCGCCGGGTGATCGAGGTAAGGGAGCGTGTACTTCGACCAGGTCCAGTACCAGTTCGGGTGCGAGCACCACGTGACGTCGAGCGGCTCGTCGTACCGGAACGGGAGCTCGACCCGCTTCGCCTCGAGCTCGTCGAACACGACGCGGTTGTACAGCCGGCGGACGGGGACGAGCCGCCCGCCCACGCGGCGGAACAGCCGGTCCTTCTCCCGGACGAGCGCCGTCGGGCAGACCGCGTCGACGCCGACGAGGAGCTTCGTCGCCATGAAGTCCGGGTAGGTCTTCTGCTTCTCCGGCGAGAGGTCGAGGAGCACCACCGACTCCTCGGGCTCGCCCGCGAGGATCGCGCGGCGCAGGTGCGCGACGACATCGTCGCGGCTCCGGCCCCCGAAGCAGCACGTCCAGCGCCGGTCGAGCCCCGGCATGCCGGCCAGCACCTCGGCCACGATCTCGGTCTGCACGAGCATGAGCGCGTAGAGCGACGGGAACGCCTGCAGCTCGACCACCTTGACGTCGAGCTCGCCGTCCGGGCCGCGCACGATCGCGAAGTCCACCTGCGCGCAGTTCGGGAGCGCGTCCATGCCGGGGGCGTCGAGGTGCGCGGGGATGGCGCGCTTCATCTGCGCGATGAGCGCGGGGCTCGAGATCTGCTGCACGATCTCCGTCGCGGAGCGCTCGAGGCGCTCGCGCAGCCGAGCCGGCAGGAACAGCGGCGTCTCGGCGACGCGGAACGGGATCGCGCAGCCGAGCCGCCGCTCGAGGCGGCTCAGGATCTCCGCGTAGGTCGACGGGCCGAAGGCCGCGTTGAAGGCGCGCCGGAAGGTGGGCTCCATGAATTTTGGTGGTATCACGGCGGCGCGCGCGGCTGCACGACGGACGGCGCCGCCGGCTCGAGCGCGGGAAGCGTCCGCGTCGATCCGATCCGGCTTGAGGCTCCGGGCGCGGCGACTACAGTCGCGGCGAACCCACGCCGAGGCCCCCACGATGATCAAGCTCCGCTCCGCCATGGTCCTGCCGCTGGTCGCCGCGCTCGCCGCGGCGTGCTCGAAGACGCCCGAGCCGACGGCCACGTCGGCGCCCGAGCCGCCCGCGGCGAACACGGGCGCCGCCCCCGCCCCGACGACCCAGGCCCCGAAGCCGGCGCACCCCGGCGGCCAGCAGGCGGCCGGGGCGGAGCTCGCCTGGGACGCGCCCGCGAGCTTCGAGAGCGCGCCGAACCCCAACGCGATGCGCAAGGCGACCTACAAGATCAAGCGCGCCGCGGGCGACACCGAGGACGCCGAGCTCAGCGTGATGCCGGCCGGCGGCAGCGTGGACGCGAACATCACGCGCTGGGTCGGCCAGTTCTCCCAGAAGAGCGACGACTCCCCGAAGCGCACCGATCTCAAGGTCAACGACATCAAGGTCGCGGTCGTCGAGATCAAGGGGACGTTCGCCGGCTCCGGGATGCCCGGCATGCCCGCCGGGGAGCCGAAGTCGAGCTACGCCATGCTCGGCGCGATCGCCGAGACGCCCTCCGGCGACCTCTGGTTCTTCAAGATGACCGGCCCCGAGAAGACGGTCACCGGGGCGCGCGCCGACTTCGACAAGCTCCTGAACAGCCTGCGGCTGAAGTGATCGACCGCGCGGCCGCCGCGCGCCGAGCCTCCGCGGAGAGCGCTCGGCCGCGCGCGCCGCGCCCTCCCGCGAGCGGGCTCGGCCGCGCGCCGCGCCTCAGCACGCGACGTCGCCCTCGAAGAACCGCGCGAACGCGGGCGGAAGCGCCGCGGCGCCGCCCTCGGCGAGCGGCGGGCGCGCGCTCGAGAGCGTCTGCCAGAGGAGGATCGTCTCCCCCGGGTGATCCCGCCCGATCTCGCGCAGCGCGACGAGCGCCTTGGCGCTGTACGTGATCTCCCCCGGGACGCCGATCAGCCGCTCCACCTCGGGGATCGCGGCGATCGACGCGGGGGTCGGCGCGCCGTAGCCGGGGCCGATCGCGCGGTGATCGATCGCGAAGCGGACGGGCGGGAGCCGCCGCCGGGTGAAGCGCGGGGCGCGCCGGGCGAGGAGGCGCTCCATGCTGCCGACCTCGTAGCGGACGACGGCGCGGTTCGAGGCGACGCGCTCGGTGATGCGCACGCCGACGATCGTGGTCGGCCACCCGAGCATCGCCGCGCCGAGCGCGAGCCCCGCCAGCGTCCCGCCCGTCCCCGAGGGGACGACGATGCGATCGGGGCGCGGCGCCTCGCCGCGCCGGACCTGCTCGGCGAGCTCGAGCATCGCGTCGACGTAGCCGAGGCACGGCAGCGCGGCCGAGGCGCCGGGCAGGATGAAGTAGGGCCGATCGGCCCGGCGCAGCGCCCGGATCGCCCGCACCGCGGTGGTCGCGTACCCGCCGCCGTGGACGAGCTCGGCGCCGCTGGCCGCGCCGGCGAGGAGCGCGTCGCGGCCGAAGCGGGTGATCGGCTGGTCGAACAGGACCGCGGTGACGGCGAAGCCGAGCGCCCGGCCGAAGAGGGCCGTGGCCGTGACCTGCGTCGACGCCAGCCCGCCGACCGTGACGAGCGTCCTCGCCCCGCGCCGCTCCGCGTCCGCGAGCAGGAACTCGAAGCGCCGCACCTTGTTGCCGCCGTAGAGCGGCGAGATCCGGTCGTCGCGCTTGACCCAGACGCCGCCGCGGCCGAGGTAGCCCTCGATCGCCGCGCAGGGGACGACCGGCGTCGGCGCGTGCGCGAGCGGGCGCCAGGGGATCTGCCCCGCGAGCTCGGGCAGCTCGGCGAAGAGCGGCAGCTCGCGCGACGCGGGCAGGAAGCCCGGGGTCGCGCCGGCGACGCCCGCCGCGCCGTCGATGCCCGCCGCGCCGGTTGCCCCGGCGCGGTCGGCCCGCCCCTCCTCGTCGCTCGCCACCCCTCGCCCCTCGCCCCTCGCCCCTCGCCCCTCGCGCTCAGGCGCGCGCCGCCGCGCCGTGCCCCGCCGACGGGCCGCCCGGCCCCGCCTGCTCGCCGGCGTCGCCGGGATCGTCCTCCGCCCCGGCGCCGAGCCGGCCGCCGCGCACGACCAGCGGATCGCGGAGGTACGTGTCGGTCAGCCGCTTCGGGCCCGCGAGGCCGAGCAGCCGGAGCGGCAAGAGGAGCACCGAGAGCACCCACGACGCGAGGCCGAGCGCGAGCTTGCCCGCGTACGCCTCCGCCACGAGCGCGAGCTTGCGGGCGGCCGACATCGACGAGATCGGCGCGTCGGTCAGGCCGATGCGCATCAGCCGGAGCTCCGCGATCCGCACGGAGTGGCGCACCAGGTCGGGCAGGCGCCGGAGCGCCGGGTGGTCCATCGGCAGGCGCTTCTTCATGAACGCCTCGAGCCGCGACACGCCCCAGAGCGACACGAGCGCGAGGCCGAGCAGCCGCCGCCGGAGCGCGGGCCGCCCCGCGATCGCCTTCCTCGTCTGCTGCTCGCCGAAGTCGACGTGGCGCTCCTCCTGCCGCACGCCCCGCTTCAGGATCGCGACGATCTCCGGCTCGTCCACGGTGTCGATCATCGCGTAGAACGCCTGGAGGACGAGGCCCTCGCCGAGGGCCATCTCGAGGGCGACGTGCTCGGACCAGTCGCCGCCCATGAGGCCGGTGGCGAGGAAGCGCACGCTCCAGGCGGCCTTCTCCGGCGGCGCGCCGAGGATCTCGAGGATGCGGAGGAAGTTGCCGACGTGCTGGAACTCCTCGACGGCCTGGCGCGCGAGGAAGCGCGCGGACTCGAGATCCGGCGCGTTGTAGAGCCAGTGGCCGATCTGGACGCCGGTGATCTCGCCGTAGAGGAACTGCTGGACGGCCCAGACGATGACGTCCTTGTCCTTGACGGGATCGAGCTTGGCGCCCTGGAAATCGAACGCCATCTCTTCGCGGGTCACCAGCATCGATCGGCCTCCAGAGCGATGAATTTAGCCCAGATCGCGGCCCCGGGCAGGCCCGAGGCGCGCGGGCCCGGCGACCGAGCCCACCGAGCCTACCGCCCGAGCGCCCGCCGCGCCCGGGCTCCGGCTCGGCCCGCCCGGGCGGAGCCGGCGTCCGCCGTGGTATACGGCCGCGGCGGCGGCATCAGGAGCCGCCGACTCGAACCTCAGGAGAAGCACCATGGCGCGCGTCCACAACTTCAACGCCGGCCCAGCCGGGCTCCCCCTCCCCGCCCTCGAGCGCGCTCAGCGCGAGCTCATCGACTTCGAGGGGACGGGCATGTCGATCATGGAGCACAGCCACCGCGGCAAGGCGTTCGATGCGGTGCACAACGAGGCGATCGCGCTGCTCCGGCAGCTGCTCGGCCTCTCGGACGACTACCACGTGCTGTTCATGCAGGGCGGCGCGGCCATGCAGTTCGCCGTCGTGCCGATGAACCTCCTGCCGCCCGGCAGGAGCGCCGACTACATCCTCACGGGCGGCTGGTCCGAGAAGGCCCTGGAGGAGGCGAAGCGCGTCGGCGCCGTCCGCGTCGCCGCGAGCACCGCGGTCGACAAGCGCTACACCCGCATCCCCCACCAGAGCGAGCTCTCGCTCGACCCGAACGCCGCGTATGTCCACATGACGACGAACAACACGCTGTTCGGGACGCAATGGCACTGGCTGCCCGAGACCGGCAACGTGCCGCTCGTCGCCGACATGTCGTCCGACATCCTGTGGCGAAAAATGGATATGTCCAGGTTTGCCCTGATTTACGCGGGCGCCCAGAAGAACATCGGGCCGAGCGGGATCACGGTCGTGATCGCCCGCAAGGACATCGTTGACAGCGGGCGAAAAGACATTCCCGTCATTTTCCGTTATGCCACTTACGCTGCCAACAACTCGCTCTACAACACACCTCCGACATTCGCAATCTACCTCATGCGCAACGTGCTCGCGTATACGCTTGAGATCGGTGGGCTCGAGGAGGTCGAGCGACGGAATCGCAAGAAGGGTGAGCTGCTGTACGAAACCCTCGACGCGCACCCGGATGTGTTCCGGGCCCCGGTCGAGAAGGAGAGCCGCTCGTTCATGAACGTGGTGTTCCGGCTGGCCAGCGAGGAGATGGAAAAACGCTTCGTCGCGGAGGCGGCAAAGGAGGGTATGGTGGGGCTCGCCGGACACAGGTCGACCGGGGGTATCCGGGTTTCGATCTACAACGCAGTATCCGTTGAATCGGTGGAGCGCCTTACGGCGTTCATGCGGGACTTCGCCAAGAGGGCCTGATCGCGCTGGGAACACGACATTCTCTGTATTTCCAGGTTCGCCCAGGTTTCCACCTGCGTCTCCGGCGAACCTCCCCTCAATTCGTCGCGTCCCAACCTTCAGCCCGCTTGACGTTGTTCCGCCCGGTACAACAGGCCCCCGCGGAAAGGGCCTGTCGGCCTTTCCGCAGCTGGGAGGGAGGCGGTGAACGCCGCTTCCCGCTCGGCGCCGGGAGGGGATGGCGAACGCTGAATCCCCGACCGGAACCCGGGAGGGGACGGCCATGCCGGCCTCGGACCCGCCCGGGAGGGGACGGCGAGCGCCGCCCCCTCCCGGCTCAGAGGCCCCGTTCGGAGACCTGAATCGAGCGAGCCAACCGTAAGGAGAGGATGATGGCGAGCATGGATGATCGTGGGATGATTTCCAGGAGTGAGGAGGACCAGGAGGAGAGAGGGGCCTCGCCGAGCGAGCCCCCGCCTTCGTCAGCCGCGCAGAAGCAGGCAAATGAGCGGCAGCAGCGTGGGTTTGCCGCCATGGATGAGGAGCGTCAGCGCAAGATCGCCAGCAAGGGCGGGAAGGCAGCCCACGAGAAAGGCACGGCCCACGAGTTCACGCGCGACGAGGCCCGTGCCGCCGGCAAGAAGGGCGGTGAGGTCGTCAGCCAGAACCGCAAGCACATGGCCGAGATCGGTCGCCGGGGCGGCGAGCGCGTGAGCCAGGACCGGGCTCACATGGCCGAGATCGGCCGCAAGGGCGGCGAGGCCGTGAGCGGCGACCGCCAGCACATGGCCGAGATCGGTCGCCGGGGTGGCGAGTCGCGGGGAGATCAGCCGCGGGAGAATCAGCCGCGTTGATCGAGGGGGGCGAGCGGCCCGGCGCCGAGGCGCCGGGCCAGCCGTCTGCACGCTTGCGCGGTCCACGGCCCGGGGCTCCCGGCCGTGGCCGCAAGGTGCGTCTCCGTCAGCTCGGCGCGATCGCGCCCAGCGAGACGTCGCTCGGCGTCTCCTTCGGGCCGGGGATCCACTCCTCGTCCGGCTCTTCCTGCGGGAGCACGACCGGGGCGCCGTCGTAGCGCAGGCGCTTGCCGGGCCAGACGAAGGTGCGGAACAGGTAGGCGAGGAGCGAGGGCTGGTCGAGGTTCGGGTGGATGAACGGCGCCACGCGCCTCGCGTGCTCGGCCGGCAAGAGGCTCCAGTGGAGGCCGGGCTCCATGTGGTGGATGGAGTGGTAGCCGTTGTTGTACGTCCACCAGTTGACCAGCCGGCCGACGAAGTTGCGCGAGTGGTCGTACTCGCTGTCCTCGTCGCAGCCGTCGTGCTGGAGGTAGTTCATCGTGACGATCCCCCACGCGGCGTACTGGTGCGGGATCAGCACGTAGATGATGAATTTCTTCCAGTCGAGCGCGAGCAGGGCGCCCATCGCGCCGAGGAACACCGCCGACTCGAGGAGCATCTGCCGGAACCACGGCGGGTTGCGCCGGTACATCGCCTTGAAGTAGCGCATGTCGGCGGGCAGGATGTCCCGGACCACGCGGCTCATGAAGAGGAGCCCGTTCAAGAGGTTCCAGCGATAGCGCACCTTCGTCGTGCGCATCACGTCGCGCCGCGACTGCGTGTACTTGTGATGGCTGAGGTTGTGGCCGGGCACGTAGGCGCTGACCGGGTGCCCGTACGTGAGCGTGAGCGCGACCTGGAACGCGCGGTTCATCCACCGCCGCCGGAAGACCGGGCAATGGACCGAGTTGTGGGTCGCGACGGCGCCGAGGAACGAGAACACGCACGTCATCGCGAGGAGCGGAATCGCGAGCCAGAGCGCGCGCGGCGCGTAGACCCATTGCACCGCCACGAGGGCGAAATAGGTCGCGACGAAGAGGAGCGTCTTGATGTCGGCGCGGTAGCGGAGCATGGCTGTTCTTCACGGGTGCGAGGGCCCCGCGCGCCGGACAGACCGGCAGCGCGGCGGGCGCTGGCCAGTCCGAACGGGCGCGGCGGCCCGTCATCCATCGTCTCGGCCCCCTTCGTACCGCATTTCGTCACAGCCGGAAGCCCCGAAGTTGTATTCCGACGGGCGCTGCGCGCCGTCGCGCGCGACACGCGTGTTTCACGCCGATGTCCCGCGCGCGGTGCGATCGACGCTACGCACCTCGCGCCGGAGATCGCCCCGGGCGCGGACGTGGTTCCGCGGGCGCTCTGCGGAGCGCGGCGGCGCGCTCCGGCGCGCTCCGGCGCGCTCCGGCGCGGGTTCGGCGGGCATGGCTCGCGCTTGACGATCCCTGCGCGAACCGCCAACGTGGCCGCGTGAGCTCATCCCCTCTCGGTTTCGATCCGAACGGCCCCGCGGTCGGCCACGGGATCTACGGGCTGCCGCACACCGCCGAGGACGCTCGGGTGGTCCTCATCCCGGTGCCCTGGGAGCCGACGGTGTCCTACCGCCGCGGCGCCGCCAAGGGGCCGGCGGCGATCCTGCGGGCCAGCCGGCAGATCGACCTCTTCGACCTGCACACGGGCCGGCCGTACGAGCAGGGCATCGCGATGCTCGACGTCGACCCGGACATCGTCCGCTGGAACGCGGAGGCGTGCGCGGCCGCCGAGCCGGTGATCGCGGCGCAGGGCGAGGTCGCCGGCGACCGGGACCTGGAGGCGCGGCTCGCGGCGGTGAACGCGCTGTCGCGCCGGCTGAACGAGCGCGTCGCCGAGATCGCGAAGCGGTGGATGGAGCGGGGCAAGCTGGTCGGGCTGGTGGGCGGCGACCACTCCGCGCCCTACGGCACGATCGCGGCGCACGCCGAGCGCTACCCCGGGATGGGGATCCTCCACGTCGACGCGCACGCCGACCTGCGCGATGCGTACGAGGGGTTCACCGACTCCCACGCTTCGATCATGCGCAACGTCGCGACCCGGCACCCGAAGATCTCGCGGATCGTCCAGGTCGGGCTGCGCGACATGAGCGAGGACGAGCTCCGGTTCATCCGCGAGTCGAACGGCCGCGTGGTCGCGCACGTCGACGCCGCGATCGCCGATCGGCTCTTCGAGGGCGAGCCGTTCCACCTGATCGCCGACGCGATCGTGGAGGACCTCCCGGACGACGTCTACGTGACCTTCGACATCGACGGGCTCGATCCGACGCTGTGCCCGAGCACCGGCACGCCCGTGCCCGGGGGCCTGTCGTTCCAGCAGGCCGTCGCGCTGATCGGCCGCATCCACAGGAGCGGCCGCCGCATCGTCGGCTTCGACCTGAACGAGGTCGCCCCCAAGGACGACCACGACGAGTGGGACGGCAACGTCGGCGCCCGCCTGCTCTACAAGCTGATCGGCTTCACGCTGCTCTCGCAGGACAACGCCCAGAACAATCGTTAGGGCGGCGCTGGGAGGCGGCGTGGCGCCGATCTGGAATGATCAGGTCAGGGCGCGGCGGTAGGTCTCTATCGCGAGGTGCACGTCGAGGGTGCCGGCCATCTCGCGGCAGGAGTGCATGCTCAGCATCGGCGCGCCGACGTCGACCGTGGCCATGCCGAGCGCGGCCGCGGTGATCGGGCCGATCGTGCTGCCGCACGGGAGGTCGCTGCGCACGACGAAGCGCTGCGGGGCGTAGCCCGCGTCGTGGCAGTGCGCCTCGAGCTCCGCCGCCGTCGCGCCGTCGGTCGCGTAGGACTGGTTCGCGTTCGACTTGATCACGAGCCCGCGGTTGACCTGCGGGGCGTGGCGCGGCTCGTGCTGGTCCGCGTAGTTCGGGTGCACCGCGTGGGCCATGTCCGCCGAGACGAGCAGCGAGCCCGCCATCGCCCGGGCGAACGCCTGCGGCTCGCGCGCCGGGAACGTGTCGACGATCCGCGCGAGCACGTCGCGCAGCACGCTGCCCGCCGCGCCCACCGCGCTCCGGCTGCCGCACTCCTCGTGGTCGTAGAGCGCGATGACCCGCGTCGCCGCGCCGGGAGCGCCCGCGCCGATCAGCGCGGCCGTCGCGGCGTGGCAGCTCGCGAGGTTGTCCAGGCGGGACGCGAAGATGAACTCGTCGGCGAGCCCGCCGATCGACGCCCTGAGCGTGTCGTACAGGCAGAGATCGAAGCCGAGGACGGCGTCGCGCGGCGCGTCGACCGCGCGCGCGAGCAGGGCGCTCAGGTCCGCCTCGCGGCCGAGGCCGATCACGGGGGCGAGGTGCTTCTGCGCGTTCAGCACGAGCCCCTCGGAGTTGACCCCGCGGTTCAGGTGGATCGCGAGGTTCGGGACGCGCGCGACGGGGCGGCCGAGGTCGACGAGGTGGCGCTCGACCCGGCCGTCCCTGCGGATGTGGACGCGGCCGGCCACGCTGAGGTCGCGATCGAGCCAGGTCGAGTACAGCACGCCGCCGTAGACCTCGACCCCGAGCTGCTGGTAGCCGCTCCGCGAGAGCTCGGCGCTCGGCTTCACCCGGAGGTTCGGCGAGTCGGTGTGCGCGCCGATGACACGGAAGCCGCCGACCGCCGGGTGCTCGGCCCCGGCGACGAACGCGACGATCGTCGACCCGCCCCGGATGACGTAGCGGCGATCGCCCGGCGCGATCGCCCACGCGTCGCGCTCCCCGAGCTCCGAGAAGCCCGCCGCCGCGAGCCGCGAGGCGACCTCTCGGACGGCGTGGTACGGCGTCGGCGAGCGATCGATGAAGGCGCAGAGGTCGCGCGCGGCCAGGGCGCCGCGCTCGCGCAGCGCCGACATCTCGTCGGCGCTCTTCGCGAAGCGCTCGCCAAGGTCGGTCGAGGGCTTGGGATCGCCTGGGCGATCGAGGATCTCGGGGGTCGTCATGAGGTGGGGGCGCCGAGTCTAGCAGAGCCTCCGCGCGCCCCGCGCGACGCGCGACGCGCGCTCGCCTTGCCGCGCCCGCGCTCGACGCGCGCTCGGTCCGCGCCCGCGCGCGGCCAGGCGAGCCCGTCGCGCGCGCTCGCGCCGACATGGCGGCCCACGCGGCCTTTGCGCCATGGTATCGCCCACCGCCGCGCCGCGCCGGACCCTCCGGCCCCGCGCCGCAACGGAGACGCGCCCCGATGTACCGCCTCGTCCGACCGCTCCTCTTCGCGCTGCCGCCCCGCCTGGCGCACGAGCTCGGCATGCTCGCGCTCGCCCCGCTCGAGCACGCCGCCCCGCTCCGCGCCCTCGTGCGCGCCCGCCTCGCGCCCCGGGACGGGCGCATCGCGGTGCGCGCCATGGGGCTCGATTTCCCCTCCCCGCTCGGCGTGGCCGGCGGCTTCGACAAGGACGCGCGCCGGGCCCGCGCGCTCGCCGCCCTGGGCTTCGGCTTCGTCGAGCTCGGGACCGTCACGGCGCAGCCCCAGGCCGAGAACCCGCCGCCGAACCTCTTCCGCCTGCCCGCCGACCGGGCGCTCATCAACCGGCTCGGCTTCCCGAACCAGGGCGCGGCGCGCGTCACCGAGCGGCTCCTCGACCGGGGCGGCGCCGCGGCGGTCGGCGTGCCCGTCGGCATGTCGATCGGCAAGTCCCGCGTCGCCCCGCTCGATCCGATCGAGCCCGCGATCGAGGACTACCTCGCGAGCTTCCGGGAGGTGCGGCGCGCGGCCGACTTCGTCGTGATCAACGTCTCGTCGCCGAACACGAAGGACCTCCGGGCCATGCAGGGGCCGGCGATCGCGCGGGCGCTCCTCTCGGCGATCATGCGGGAGAACCGCGGCGCGGGGAGGCCGCTGCCGCTGCTCGTCAAGGTCGCCCCGGACCTCGGCGACGAGGAGCTCGAGGCGCTGCTCGCCGTCGTGGAGGAGGTCGGCCTCGCCGGCGTCATCGCGACGAACACGACCGTGCGGCGCGACGGGCTCGCGACGAGCCCGTCCGCCGTCGAGGCGATGGGCGCCGGCGGGCTCAGCGGCCCGCCGCTCAGGCAGCGCTCGCTCGCGATGGTGCGGCGGATCCGCGCGCGCCTCGGCGGCGGCGTCACGGTGATCGGCGCCGGCGGCGTCGAGTCGGCGGAGCACGCGATGGACCAGATCGAGGCGGGCGCCGACCTCGTGCAGCTCTACACGGGCTTCGTCTACGGCGGCCCCCTCCTCCCCGCCGCGATCGCGCGCGGGCTGTCGGAGCTCGTGGCGCGCGCCGGCGCGCGGTCGATCCACGATCTCGTCGGAGGCCGGACGGGCAGCGCTGCGCGCGCTGCTATGATCGGCCATGGAGCTTGAAGCGCACGTCCACGACACCATCCGCGAGATCCCGGAGAGCGAGTGGAACGCGCTCCACGGCGCGAGCGAAGCGCCGTTCCTCTCGTGGGCGTGGTTCGACGCGCTCGAGCGGACGGGGTGCGTGGGCGAGGAGGCGGGCTGGTTGCCGCACCACATCACGCTCCGGGTCGAGGGGGTCCTGCTCGCCGCCGCGCCCGCGTATCTGAAGGACAACAGCGAGGGGGAGTTCGTCTTCGATCACGGCTGGGCGTCGGCGTCCCACCAGCTCGGCGCGCCGTACTACCCGAAGCTCGTCGTGGCGGTGCCGTTCACGCCCGCCACGTCGCCGCGCCTGCTCGTGCGCCGGCCCGAGGATCGCCCGGCGCTCCTCGCGGTGTTCGCCGAGACGCTCCGCGAGCTGGTGGCGCGGAGCCGCATCTCGGGCGCCCACGTCCTGTTCCCGACCGAGGACGAGGCCGCCGCCCTGTCGGGGGCGGCGATGGCCCACCGCTGCGGTATCCAGTTCCAGTTCGAGAACGAGGGGTACGGGTCGCTCGACGACTTCCTCGCGCGCTTCAACGCGAAGCGGCGGCACCAGATCCGGCGCGAGATGCGCGAGGTCACGCAGCAGGGCCTGTCGATCGAGACGCTGCGCGGCGCGGACATCACGCCCGAGATCGTGGACGTGATGTTCGGCTACTACGTCTCCACGGTGGAGAAGTTCGCCTGGGGCCGGCAGTACCTGAACCGCGCCTTCTTCGAGGAGATAACGGCCCGGCTCCGCTCGTCCGGGGAGCGCGCCGGGGGCGAGGGCGGCGTCGAGGTCGTCCTCGCGCGCGACGGCAAACGGCCCATCGCGGGCGCGTTCAACCTCGCCGGGCCGACGACCCTCTACGGCCGTTACTGGGGCGCCTCGGAGGAGCGCCCCTTCCTGCATTTCAACGTCTGCTACTACCACCCGGTCGAGGACTGCATCGCCCGCGGACTGCGCCGCTTCGAGCCGGGCGCGGGCGGGTCGCACAAGCTCGTACGCGGATTCGCTCCGAGGATCACCCACAGCGCCCACCACCTCGCGCACCCGCGCCTCGACGCGGCCGTGCGCGATTTCCTGGTGCGCGAGCGCGCCGTCGTGCGCGCGAAGACGGCGGACGCGAGCGTGGCATTCCGCTGAGCGCGCCTCTCGACGCGCGGTGTTGACGTGACGCGCTCCCGGGAGAGATGCTGTCGGGCATGCGTGCCTTTCTTGCCCTCCTCACCTCCTCCATCGTCGTCGGGCTCGCCGCGAGCGGCGGCTGCTCGAGCAGCCCGGCGGCCGACGCGACCTCGACGGCCGCGGCGGCGACGGTCGCCGGCGCCGGCGGCTCGCTCGGCTTCGGCTGCTTCGGCGGCAGCCCGGACGGCCGGTGCACGATCCTCGCCCAGGTCTCCGAGGACTGCGGTTGCCCCGATTGCGCGGATTCGGCGAGCTGCCTCGGCTTCTGCAAGGACGACGGCGCCTGCGATCTGCGGCCCGACGCGCCGGACGGCGAGGATTGCACCTGCCAGGACTGCGCCAACAGCGTCGCCGAGTGCAGCCCGTCGCGCGGGTGCAACAGCAACATGGGGTGCAACGCCAACGAGGATTGCACCTGCCCCGATTGCACGGACACGCCGCGGTGCACGGACCATTGCACGGACAACGGCTCGTGCGCGCCGTACTTCGAGGGTTGCTCCTGCGCCGATTGCCGCTCCGCGGAGCGCTGCGGCGGCGGCGGCCCGGCCACGACCACCGCGGCCACCACCGGCGGCGGCGAGGGCGGCGGCGGCGGCGGCGCGGGCGGCGCCCCGGCCGGCACCGGCGGCAGCGGCGAGGCCGGCGGCCCGGCCGGCACCGGCGGGGCCGGCGGCGGCGGCGGGGCCCCCGGGACGGGCGGCGCGGGCGGGGCCTAGAAGGGCAGTCGTCCAGGAGAGAAGAAAGACGAACCACAGAGGCACAGAGGGCACAGAGGGGAGAAAAGAATTCTTACCTCTGTGCCCTCTGTGCCTCCGTGGTTCAAATTCTCTGGCCTCTGCGGCTCGAATTCTCTGTCAGCGTTTCACGAGGACGTGCCCGTGATGCCTGGAGGCGAGCGGCCGCAGCCGGAAGACGTGTGCCGTCTCACGGCTTCGCGGTCAGCCCGTGCTTCCTCAAGAACATCCGCACGTGGTGGCGCTCCATGCCGGCGCGGCGCGCCATCTCGCTGACGTTGCCGCCCGTGGCGCGGATCAGCTCGCTGAAGTAGCGCTGCTCGAACGCCGCCACGGCGCTCCGCTTCGCCTCGCCGAAGGCCGACGTCGGCGCGACGACGTCGCCGCCGCCCTCGAGCGGGAGGATCGCCGCGATCGCCTCGGCCCCCGGCGGCAGGCTCGCGGCCACGCTGGTGACGTTCATGAGCTCGCGGACGTTGCCCGGGAAATCGTGCTGGCCGAGCGTCGTGGTGATGAGATTGACCATCTCCACCGAGCGCTCCGGACAGCCGAGGCGCGCGCAGACGCTCTCGACCAGCAGCGGGATGTCCTCGCGCCGCTCCCGCAGCGGCGGCAGCTCGATGCGCATCTGGGCGATCCGGAAGAAGAGATCGCTCCGGAAGCGCCCGGTGTTCATGCTGCGGCCGAGATCGCGCCGCGTCGCCGCGATGATCCGCACGTCGACAGGCTCGTAGACCCGCGACCCGACGCGCTTGAGCTTCCGCTCGGACAGCACGCGGAGCAGCTTCGGCTGGAGCTCGGGCGGCAGCTCGCCGAGCTCATCGAGGAAGATCGTCCCGCCGTTCGCCTCGTGGAAGGCGCCGCCCTTGCGCTCGGTCGCCCCGGGGAAGGCGTCCCGCTCGTGCCCGAACAGGAAGCTCTCCGCCAGCGCGCCGGGCAGCGAGGCGCAGTCGACGACGACGAACGGACCGCCGCGCCGGCTCGAGCTGTCGTGGATCGCCTGCGCCGCGAGCTCCTTGCCCGTGCCGGTCTCGCCGGTGATGAGCAGCGACAGCTCCGTCGCGGCCACCTCGCGCAGCAGGCGGAACAGGTGGCGCATCCGCGGCGAGGCGCCGATCAGCGGGCCGAAGCTCTCGTCGAAGCCGACGTCGACGCGCTCCTTGTCGAGCGGCTCGAAGCCCAGCACCGAGCCGCCGACCTGGATGGCGCACGCGGCCGTCAGGATCGCCTCGCGGATGCGCACCGTCGACACGAACGTCCCATTCTTGCTGCCGAGGTCGCGGACGAGGACGCCGGGCCCCTCGGCCCGCAGCTCGCAATGCGTCGAGCTGACCTCCGGATCGTCGACGACCACATCGCAGCTGGGATCGCGCCCCACCACGACCGGCGCGATGCCGATCTTGACCGGATCCCGGCCAGCCGCCCGCAGCGTGCCGCCGCGAACGAACCACTGCACCGCGCGAGCGCGGGTCGCATCCCTCGTCGAGCTCATATCCAACGGTTATTCGATTTCCCCGGACTTGACCACATCCACGTACGACCCCGCCACCACATGGCCGCGCCTACCTGGGCGCACCGGGTACGCGCATTCCGGAGGAGCCGCAGCGTCGCGTCAAAAAACTTCACAATCACGATAGATATCAGGAAAAAATTCACATCAAGCGATGTACGGAGCGCATGGCGGGAGAACCCCTAGAGAGGTTAGACTACGGGGCTACGCAGGAGATGAAGCGGGCGATTGTCCAGTCCGCTCCATCGGGCGTCGTTGAACGACAGCCCACCTTGGCTGCTTCGACGGGTTGTCGATCAACGAGGTCCCGGGGGTCCGCACCCCTGGTCCCTTCAACGCGGGGGCGCGCGCAGGCGCCCCCGGCGAGGATGCTTATGCCGAGAACAGGATGGTACCTCCGGAAGCGCGCCGCGACGGCCCTGGGGCTCCTCGGGCTCACCGCGGGCGCGGGCGCGCTCGCGGCCGGGTCGAGCGGCTGCACCGGCGACGCGGGCGGCCCGTGCATCTCCGACGAGCAGTTCTTCGCCGAGAAGGTGTGGGTCCCCATCCTCTCGACGAAGTGCATCGGCTGCCATAACCCGCAGGGGCAGGCCGCGAAATCGAAGCTGATCCTCGCCGGGAGCAGCGAGGCGGGCTTCCTCGACAAGAACCTCGCGACGTTCAAATCGCTCGCGGGGCTCGAGCTGAGCGGCGAGTCGTACGTGCTCCTCAAGCCGACGAAGAAGGTCGACCACGGCGGCGGCCACGTCATCGACGCGGACAGCGCCGACTACGAGGCGCTCCGGGAGATGGTCGACCGCACGAAGGAGCCGTCGTCCTGCGAGACGGACGTCAACGCGTCCTTCGCCGGCGTGGTGATGAGCGGGCCCGAGGACACGCTCCGCGCCGCGGCCCTCGAGATCGCCGGCCGCCTGCCCACCGAGGCCGAGGCGCAGGCCGTCGCGCAGAGCGGCATGGACGCGCTCGACCCGATCCTGGACCAGATGCTCACGGAGGAGGCATTTTACGTGAGGCTGAAGGAGATCTACAACGATCTCTTCCTCACCGACCGCTACCTGAACGGCGAGGCGGCCGTCGATCTGCTGAAGAGCGACGCGTACGACGCCAAGTGGTACAACAGCCTCCCGCAGGATCCCGCGCTGGTCGAGAAATACGGCGCGCGCGACCTGGAGGACGCCATCAACAAGGTGAAGAGCTGGACGAACCGGGGCGTCGGGCGGGAGCCGCTCGAGCTCATCGCCTACATCGTGCGCAACGACCGGTCGTTCAAGGAGGTCCTCACGGCCGATTACACGGTCGTGAACCCGTTCTCCGCGAAGGCGTACGGCGTGACGGCCGAGTTCCAGAACGACGCGGATCCGGAGGAGTTCGTCCCGGTGAAGCGCGACCCGATCCCGCTCGCGGGCGTGCTCACCTCGCCGGTCTTCCTCAACAGGCACCCGACGACGAGCACCAACAGGAACCGCCACCGGGCGAGGGTGGTCTATCAGTACTTCCTCGGCACCGACATCCTGAAGACCGCCGAGCAGCCGCTCGATCAGACGAAGATCACCGATTTCAACCCGACGATGAACAACGCGGCGTGCACCGTCTGCCACGCCGCCCTGGACCCGCTGTCCGGCGGGTTCCACAGCTTCGACTCCGCGGGCCGCTACGAGGCGGACGACACCTGGTACGAGGACATGCGGCCGCCGGGCTTCGGCGCCGAGTCGGTGCCGTTCAGCGAGTTCCCGAGCGCGCTCTCGTGGGTCGCGCAGCGCGTCGCCGACGACCCGCGCTTCGCGCTCGCGGCCGTCTACACGATGTACACGGGCCTCACCGGGCAAAAGCCGCTCGTCGCGCCGACGAACGACGATCCGGAGTTCAGCGCCAAGTTCCGGGCGTACCTCGCCCAGTACCACGCGTTCAACGCGATGGCGCATGACTTCGCCGACAGCGATTACAACCTGAAGACGGTCGTCAAGGCCATCGTCAAGAGCCCCTATTTCCGCGCGCGCAACGTCGCGCAGGCGTCGTCCCAGGGCGATCCGCTCGCGCAGCTCGGCGGCACGCGGTTCCTCGGGCCCGAGCAGCTGCACCGGAAGATCTGGGCGGTGACCGGGTATCCGTGGCGGCCGAGGGCGTTCGAGGACGACGGCAACCGCTATGACTACCTGCTCCGGCGCGACGCCTACCGCCTGCTGTACGGCGGCATCGACTCGGAGGAGGTGATCCAGCGGATCACCGAGCCGAACGGGATCATGGCCAACGTCGCCGACCGGATGGCGAACGAGATGGCGTGCATCTCGGTGCCGCGCGATCTCTGGCTCCCGCAGGAGGAGCGGCTCCTCTTCCCGTTCGTCGAGACGACGTTCGAGCCGCGGGACACGAACGATTTCGACGTGCTGCCGGCGGTCGAGGCGATCAAGAAGAACATCCAGTACCTGCACGAGCGGGTGCTGGGCGAGTCGCTCGAGATCGGGGATCCGGAGATCGAGCGGACCTACAAGCTCTTCGTCGAGACGTGGGAGGAGGGCAAGGCGGGCATGAAGAAGCCGGAGGGCGAGGAGGGCCGGATCTCGACGTGGCTGCCGGGCCCCTGCGAGGTGGAGAACGACTACTGGACCCGCGACGCGCTGCCCAACGAGGAGAAGCTCCAGCGGGACGAGAACTACACGATCCGCGCGTGGATGAGCGTCATGACCTATCTCCTGTCGGACTTCAGGTTTCTTTACCAGTAGGAGCAGCCATGGAACGTCGAGATTTCCTCAAACTGGCATCTATGGCGGGCCTGGGCGTCGTCGCGGCGGGCGCGCTGTCGCGGGACGCCGCGGCGGCCGGCCCCTACGAGGGCCCCCTCTGGATCAACATCCACGCGAGCGGCGGCTGGGACCCGACGAGCCTCTGCGATCCGAAGGGCGCGATGAGCGTCGAGGAGCAGAAGACGCGGGACGCGATGAACCGCAGCTACCTGCGCGAAGAGATCGGGACCGCCGGCAACATCAAGTTCGCGCCGGTCGGCGGCAACGCCGAGTTCTTCAAGAAGCATTACAGCCGGCTGCTCATCGTCAACGGCATCGACACGTCGACGAACAGCCATGACGCGGGCGTGCGCAACACGTGGTCCGGGACGCTCCGCGAGGGCAAGCCGGGCTTCGCGGCGCTCGTGGCCGGCGTCCACGGCGGCGCGCTGCCGATGGGGTTCATCAGCAACGGCGGCTACGACACGACGGCGAACGTCGTGGCCGTGACCCGCGTGCCCGACACCGGCCTCCTGCAGCGGCTCGCCTACCCGAACAGGACCGATCCGTCGAACAGCGAGAACCGCGAGCAGTACCACACCGACGCCACGATGACGCGGATCCTCGAGGCGCGGCAGGCGCGGCACATGGCGAAGCTCGATCAGCAGCGCCTGCCCCACGTGAAGCAGGCGATGAGCACGCTCTTCACCTCGCGCGTCGGGCAGAACGAGCTCAAGCAGCTCATCCAGTTCCTGCCCGCGGAGTTCGAGCGGGCGTCGCTGCGGCGGCAGGCGCAGGTCGCGCTCGCGGCCTACCAGGCCGGCATCTGCGTCAGCGCGAACCTGTCGATCGGCGGGTTCGACACCCACGGCAACCACGACGACAACCACATCCCGCGGCTCACCGACATCTGCGACGGGGTCGACTTCCTCCTGACCGCCGCGGAGGAGCAGGGCATCGCCGACCGGATCGTCATCGTCGTGGGCTCGGACTTCGGTCGGACGCCGGGCTACAACGAGGGCAACGGCAAGGACCACTGGAACATCACGAGCATGATGATGGTCGGCGCGGGCATCCCGGGGAACCGGGTGATCGGCGCGACGGACGATCGGCACAACCCGCTCGAGGTGGATCCGGTGACGCTCGAGCCCAGGGAGGGCGGCGTGCGGATCAAGCCGGGGCACATCCACAAGGCGCTGCGCAAGCTCGCGAAGGTCGCGGACGACCCGCTCGCGCAGCGATTCCCGCTCTCCGAGGAAGAGGACCTGCCGATCTTCGGCTGACGCGCGCCGCGGGCGGAGGGCGGCGGCGCGCTCGCCGGCCGCCGCCCGGCGAGGCCACGCTCACACGGAGGGGGCCTCCCCGCCGTTGCGGTAGTCGCGCAGGAACACCAGCACCTCCCGCGCGTCCTCGATCAGATCGTCGTAGGTCATCAAGGTGATGCCCGCCATGAAGCTGTTGTCGAGGGCCAAGCGGTCCCGCTCCCTTTGGCTTCCGGTCCTGCCGATGACCACGAAGCCGCGCGGCCGGTGCAACGACACGCGCACGTTCTTGCGGACCTCGTAGCTCACCTGCCCTCCGGTCTGCTTCTCGGCGAGGTCGATGTACTCCATGACCTGCCCGACGGCCCGCGCGCACTCCTCGCTGTGGTGCAGCCGGTCGCCGTACTCCTTGAAGACCTGCTGATCCGGGCGCTTCAGCTCCCAGATGTCGGGGAAGCCGTCGTGCCGGACGAAGAGCAGATCCACCTTGACGCCGCGATCGACCTCGTACGGGGAGTGGCATTCCCGGTAGCGAGGTCCGAGGAGGACGCGCCAGCTCTTTCGGAGAAAGATCCGGATCTCCTCCTCCCGGGGGTTCCGCGCGATCAGCTCCTCGAAGGCTCGCACGGTGCTGTGCGCGACGTAGGCAGGGCTCTCCAGCGCCACCGCGACGGCGCGGAGCACCGCCGCGCGGAGGTCCTGGTCATCCTTGAACAGGAAGTGACCGCCGCGGTTGCGCTGCATCGCCTGACGCATGAGCTCGCGGTTCCGGCTGTGGGCGGTCGCGACCACGACCGGTCGGAACGGCTCGGCACGGAGGAGCGCGTCCAGCATGCGGAAGCCGTTGTCGGTGTGCTCGTCCGCCCGTCCCGGTCGTGAGGGGATCTGCAGGTCGAGCATGACGACGTCGGGCTGGAAGCGCTCGGCGACGGCGAGGCCGTCCTCCAGGGCCGAAGCTCGCTCGACTTGGTAGTGCTGCTCCCGCAGCCACTCGACCGCCGCCTCGGCGTTCGTCTCGTCGTCCTCCACGATGAGGACCCGCTTGGCTTGCCTGCCGCTCATGCGCCCTCCGTCCATGCCACGAGGTCCACATAGAAGCACGTCTCGGACGCCGTCTCATCGAGCCCCACGTGCCCGTGCATGTGCTCGGCGTAACGCCGGGCGATGGGCAGCCCGAGGCCGGTGCCGCGCGGCTTCCCTGCCCCGCCCTTCTTCGTCGTGACGAGCGGCTCGAAGATGCGCTGCCGATCCTCGGGAGGGACGCCGCATCCCGTGTCGCGGATCTCGATGCGGATCACCGCGCCGATCGGGCGCGTGACTGCCGTGACGCACGACGCTCGGTCCTCGGTGCCCATGACGGTAGCGTGGAAGGCGTTCTCCATCAGGCACTGCATCACCTCGCGGAGCGCGTCGCGCATCGCGCGAACGCGGACCGACGACTCGACGTCGATGACGAGCGTCACAGCCGGGTGGCGCGCGTTGAGCTCCCTTCCGAGCTCCTCGATCACAGGCCGCACGGCGACCTCCTCGATGGGTTCGTCGGGCGCGGTCTCCCAGAGTCGAGTGCGCTCCGCGAGGCTCTGGATGAAGCGCAGCTCCTCCTCGATCTGCTCGAAGGACCGGGCCAGGGCGGTCGCCCGCTCCCTGTCGATGCCATCGCGGATCTCGCGGAGGCGCGCGCGAACCATGCCGACCGGGCGGTTGAGGAGGTGCGCGAAGGTCAGCTGCAGCTTCCGCTCCACCTCGCTCCGGACCTTCTCGTCGAGCTGGGCGACCCGGCCCTGAGTGACCTGCGCGGAGACCTCGGGGGCGATGAGCGCGAGGAACAGGAACACGAACGGCGGGAGCTGATATCGAAGCAGGATCTCGGAGTTGCCGGCGCTCACCTCGCGAGCGATCTTCCGAGCGATGTAGTAGTCGCGCAGCAAGTGGTTCTTATGCTCGACCTTGCCGAAATCAAACCATGTCAGCAGCGAGTCCAGCGCACCTCTCGTCCTCTCGAACCTCCGGGGCACCGAGAACTCAGCCGCTCGACGCAGCCCCATGGCGAACTGCGCGAGAGCAATGTCTTCGAGGTACCGCGACAGCGCATCCTCCCCTTCCATCCCCGAAGGCGGGAGCGCTCGTTCCTCAAGCTTCATGGCATCCACATAGGCAACGACGACGGAGGCTATCCATGCGTCGATCGACGCAGGTCGGTCCGCAAGTTCGATGCTCTTGACGGCGGACACGATGCGCCCCAGGTTTGGCAATGCGCCCGACAAGGAGCGAAAGCTATCGTTTTCAGCGCGGGCGCGCAGAAGCCGACCGGTGAGCTCCTGTGAGCCCAAGCATGCACGGTACCACGAGGTAATTTCCTCGGATGACGGCGGCACGAGCACGATGCGGACGACGCCTATCCCCGGTGGAGGCGGACCGAGCGTGTCAGCCATGCGCGCCGTCAGCAGACATCGCCAGGCCTGCTCTTGCATCGGCGCGGCTCTCAAGAGCGAGGATCGCGTGATCACCGGCACGACTGCGCCCGTGTCGAGCGCGATCTGCATGACGGAGGCGAGGTACATGTTAGCGATATCGACGAGCAGGGTGGCCTGCTCCGGGTCGTGTGAGAAGCGAACGGCCGCGCGATCGATCGCATGCTTCAACGCGGCTTGCTTTCCGGAGCCCGGTGGTCCCTCGATGACGAGCATCGGTCGGTCCGGCCGATCCATCCATGCCTCGATGAAGGGCTCCAGCGGCACCACCGCGCCGTCGGCGAGCCGCCCGCGTCTGGGCAGGTACGTCTGTCCCCGCCGCTCCTGCTCGCTGGGCTGCGCCCGCTGCCTGGCATCCTCGGCGATTCCCGAGATTTCCAGCAGCCAGCGCCGGAAGGTCAGCACGTTGCTGGTTCGCCCCACGAGATCCGGGGCGTAACCACCGGGCAGTCGTTCGCTCATCACGATCGCGACCGCGCGATCGGCCTTCCGTGCCACGCGAGCCGACTCGAGCTCGGCGAGCGTCTCGTTTAGGTCTTCGGGAGAGCGAGGGAGCACTCGGAAGTAGGTGCGAGGGCGGATGAAGCTGCTGCGAGGCGTGGCAAACCAGTCGATCACCCCCTGCTCGAGCCCGACCGCTTGCTGGACTTCGTAATCACAAGCCTCGAGGACCTCGGTGACCCGCGCCTCCAGGGAAGGCGGCGTGCGCCTCTCATCTTCCATCGACCGATCCCTTCCGCTCGTAGAGCTAGCGAAGCGCAGAACCAGCGTCCAGCGACCCCACGGAGACCTCACTCCTCACGGAAGGGAACGAGAACCTCTACCCCAGGCAGCGCCCGGCAGCGCACGTTCCAGCTCGTGGAGGAGGAGCACCGCGAGCTCGGCTGGACCCCGACCCACGCCATCGCTCCCCCCTCGCCCGCCGCTCACTCCACCGAGAACGCGATCTCCTCGCCGGCGGACGCGCCGTCCGCCTCGACGCGGAGCCGGTGCGCGCCGGCGACGAGCGGCCAGTCGAGCGAGAACGGCGGGCCGACCTCGATCGGGCGGCCGTCGAGCACGAAGCGCGCGCGGCGCACGCCCGGCGGGACGTCGGCGCGGAGCCGGATGGCCTGCTGCGAGTTGACCGAGGGGTCGAGGACGAACCGGGCGCCGTCGGGCGGGTACGCGACGCGGACGCGCGCGCCGGCCGGCGGGACGCCGTCGCCGCCGGGGAGCGGGCCGCAGAGGGGTGAGGCCTCCTCGGGCGCGACGGGGCGGCCGGCGGCGCGCGCCCAGGCGGTGAGCTCCGCGTCGTAGCGCTCGAAGACGCGCTCCTCGACCGCGGCGTCCGGGCAGGCGCCGGCGCGCAGGCCGTTCCGGCGATCGACGCGCACGGCCTCGTGCATGTCGCACGGCGCGAGCGCCGCGGCGTCGGCGCGCGGGAGGAGCTCCCGCCGGCGGTGCGGGCAGACGGCGGTCGGCTTCATGCCGGACAGGCCGCACACCTCGACCTCGGCGAGGTGATCGGGATCGGGCGGATCGAAGGGGCGCGGCGGCCGGACGCGCGCGGCGGCGAGCATGGCGTCGCGGAAGAGCGGGCCAGCGCCGGTGATGCCGCTGACGCCGCCCATGGGCGAGCCGTCGAAGTTGCCGACCCAGACCGCGACCGTGACGTCGGGCGTGAAGCCGACCGCGAGGTTGTCGCGGAACCCCTTGGAGGTGCCCGTCTTCGCGGCCACGGGGAACGGCAGGTCGAGCGCGCTGCCCTCGCCGAACGAGGCGATGCGCGCCTTGTCGTCGGCGAGGATGTCGACGATCACCCGCGCGCGCGCGGCGTCGAGGACGCGCGCGCCGCGGCCGGGCGGGTCGATGGCGGCGTCCTCCGGGCCGCCCGCGGGCGACGCGAGCGAGAGCGCGCGCACGGCGCGCACCGGCAGGTAGACGCCGCCGCGCGCGAGCGTGGCGTAGGCGTTCGCGAGATCGAGGAGGCGGACCTCGCCGTCGCCGAGCGCGATCGCGACGCCGTAGCGCGACGGCTCGCGATCGAGCGAAGCGAGGCCGAGCTCGCGGAGCCGCGCGAGGACGCGCTCGGGGCCGAGCGCGGCCGCCGTCCAGACCGCCGGGACGTTGTACGAGCTGGCGAGCGCGTCCCGCAGGCGGACGGGGCCGTGGAAGCGCCCGTCGTAGTTGCGCGGCGCGTAGCTGCCGTCCGCCGTCGGGAACGAGAGCTCGACGTCGGGCAGGACGGTCGCGGCCGTGAACCCGAGCTGCTCCATGGCGAGCTCGTAGACGAACGGCTTGAGGGCGGAGCCGGGCTGGCGCAGCGCGAGGACGCCGTCGTTGTGGCCGAGCCCGGCGGCGTCCTCGATGTCGTGCGAGCCGACGTACGCGAGGATCTCGCCGGTCGCGTTCTCGAGCACGACCACGGCCGCGGCGCCGACGTCGCGGTCCGAGAGGCCGCGGACGGTCTGCTGCGCGAGGACCTCGATCTCGCGCTGGAGGCCGCGGTCGATCGTCAAGGTGATCGAGCTCGCCCGGCCGCGCAGCGGCGCCGCGCCGGAGCCGCCCGCCTCCGGACCAAGCGCGCCGCCGAGCACGGCGCGGACCAGGTGCGGCGCGCCGAGGCCGCTGCCCTTCGGGGCGAGCGCGATCGGCTCGGCGCGGGCGCGAGCGACCTCGGCCTCGCCGGCGAGGCCGGCCGCGAGCATGCGGTCGAGGACGCGGTTCCGGCGGCGCTCGAGCGGGCCGGCGCCGCGGCGCGGATCGTAGAGCGCGGGGCCGCGCGGCATGCTGGCGAGCGCGGCGGCCTCGGCGAGCGACAGGTCCGCGGTGGGCTTGTCGAAGTAGAAGCGGCTCGCGGCCTCGACGCCGCGCAGGCCCGGGCCGAACGCGACGCGGTTGAGGTACTGCTCGAGGATCTCGCGCTTCGAGAGCGACGCCTCGATGCGCAGCGCGAGCGCCATCTCGCGGAGCTTGCCGCGCACGGTGCGGGGGCGCGGCACGAGCGCGCGCGCGAGCTGCTGCGTGATCGTGGACGCGCCCGAGACGACGCGCCGCTCCGCCGCGAGCTGGCCGAGCGCGCGCGCGATCGCGATCGGATCGACGCCTGGGTGAACCGCGAACCGCCGGTCCTCCGCGGCGAGGAGCGCGCGCTGGATGCGGTCGCCGGCCTCGGCGAGCGGGGGCCAGCGCGCGCGGGCGCCGTCGCCGGCGCGGAGCTCGCGGAGCACCGTGCCGTGGCGGTCGAGCAGCACCGTGGAGACGGCGCGCTCCTCGGGAGCGGCGAGCTCCGGCGGGAGCTTCGTGAGGGCCGCGGCGACGGCGAGCAGGAGCCACGGCGCGACGGCGAGGGCGAGCGCGATCCGCGCCGCGCGGCGCAGGAGGAGCGGCAGGCGCGGGCGGGCGGCCGCGAGCCAGCGCCGCGCGCCGCCGGACCCGGGCGGGGAGAGCGCGCCCACGGCTCAGCGCGGGCGCGGCGCCGCGTCCCGGCTGCCGACCTTGACCGCGAGGGCGCCCGTTCGGCCGAAGACCTCGGGGCTGTACATCTCCTCGGCGCGCGCGGGCGGGACCACGAACGCGCCGAGCGTCGTGGCGCGCGCGAGGTACCGGTACCGGTACATCCCGGCGGCCATGTGGTCGACGAAGAACAGGACCCGGTCGTCGCGGACCTCGCGGACGAACCGGCTCGGCTCGTACGCGCGGCCGGTCGCGCGCAGGTCGTCCTGGTCGACGTCGGCGTCGGCGTCGGTGTCCGCCTGGGCCTCCGCCGCGTCGACGTCGAGCGAGCGCGCGGACGTCGCGAGGCGGGCGTCGATCGCCTCGAGGCCGGCCGGCAGCGGGTCGTCGATGACCACGAAGTCGCGCGGCGAGGGCGCCACCACGAGGATCTCGCCGAGCACGAGGTCGCCGCCGGCGAAGGCGAGCGACGAGGGCGCCGCGCCCGACCCGGCGGCGGGCGGCGCGCCGCCGAGCGCCGCGGCGAGGTCCTCGGGCGCGAGCGCGCGCAGCGATTTCTCGATATAGAAGCCGCGGTCGAGCCCCGCCGTCGGGAGCTGCTTGCGCGCGTAACGGAGCCGCGCCTCGTAGAAGAGCCGGCCGCGCCCGTCGACGGTGAACGCGAGCGGCGCGCCGCCGGCGCTCGCGAGCCGCGCCGCGGGGATCGACGTCTTGACCTGCTCGGTCGTGGGGCCGTGGAACGGCGCCGAGAACAGCTCGGCCTGGCCAAGGAACACCCGCGCCTCGAAGTCGGGCGCCGCCTTCTCCTGCGCCCTCCGGTACTGGTCGAGCGCGATCAGCGCCCACGCCGTCTCCTGCGTGCTGCGCCACGTGCCGCCGCGGCGATCCGCGAGCAGGCCGGCCGCGAGCCGCGCGGCGAGCGGGTGCGCGGGGCGGGCCGCGAGCAGCGCGCGCAGCACGAGCGCCGAGGTGCGGGCCTCGGAGTCCATGAGGACCGCGTACGCGTCGCCGTGGTTGTGGACGGCCCGCGCGATCGGGCCGTCGAGGCGCAGCGCGCCCTCGAGCTCGCCCACGAGCTGATCGACGGCCGCCCGGTCGCTCTTGCCGATCACCATCGCGTGCGCGAGCAGCGCCTTCGAGAAGAGCGGCAGCTCCTCGCGCTCGTCGAACAGCCGGCTCGCGCGCCCCGGATCCGGGGCGCCGATCTCCGCGAGCACGTCGAGGATGAACGGCGACGTCGCCCGGAGCAGCGGATCGTCGTCGGCCTCGTTGAGCCGCGCCCGCACGAACGAGGTCGCGCGCTCCACCGCGTCGGCAGGCACCGCGACCCCGTGGCGCTTCGCCTCGCCGAGGCCCCACAGCGCGTACGCGGTGGTCCACAGGTCGGCCCTGTCCGACTCGGCGAAGAAGCCGAAGCCCCCGTCCCCGCGCTGGTGCGAGAGGATCTCCCGCACCGTCTTGCCGATCACGGCGGTGAGGTCCTTCGGCAGCGCGATCCCGTACGCCTTCGCGAGATCGCGCAGCGACAGGAGCGGCACCATGCGGCTCGTCAGCTGCTCGGTGCACCCGTACGGGTACTCGAGGAGCTGCTCGACGCCGCCGCCGAGGCCCACGAGCGCCGTCGGCGCGAGGCTCACCGTGAGCCCGCCGGTGTCGTCGCGGATCGCCGACAGATCCCCGAGCTTCTCCGCGCTCGCGGTGGTCGTGTCGCCGTAGAGCGCGACGGCCTCCGGCGACATGGGCGCCCTGATCTCGCGGGTCACCTCGACGACGTCCGACGCGCCGCCGCCGCTCGCGCGGAAGCGCAGCGTCGCCGGGCCCGCCCGGGGCGCCGAGAGCGCGAAGCGGACCTCGGCCGACGCGCCCGGGGCGAGATCCACGGCGCGCTTCGCGGCGCCCTGGAGCGTGAGCCCCGACGCGGCGACCTCCACCTCGACCGTCGCCGGCTTGCCGAGCCCCTTCGACGTGACGACCACGCCCGCGTCGATCGCGTCGCCGGCGCGGAGGAAGCGGGGCAGCGCCGGCCGCGCCATGAGCGGCTGGCTCGCCGTCACGCGCGACTCGCCGTAGCCGAAGCGATCGTCCTCGGCGGCGACGACCGCCATCACCCGGTAGGTCGTGAGCGAGTCCGGCAGCTTGAAGCTCGCGCTCACCTTCCCGGCGGCGTCGGTGACGATCGCGGGGTGGTAGTACGCGCTCTGCCGGAAGTCGCGGCGCACGCCCGTGCCGCCCTGCGCGCCGCCGCCGCCCGCGCGCCCCTTGTCGGCGCCGAGGTCGGCGAACGGGTTGCGCACGCGGGCGAGCGCCTCGCGCGTCTCGACGGTCGCCACCCGCAGGCTGCGCGGCGCGCCGAAGACGGGGACCGGATCCGGCGTCTCGTAGCCGGTCAGCGACAGCACGCCCTCGTCCACGGCGTAGAGCGCGACCTCCGCGCGGGCGGGCCGGCCGGCGCGATCGCGGACGTCGACGTCCACGCGGATCGGATCGCCGGGGCGCGCGTCCACCTTGTCCGGGACGACGCGCACCGCGAGCCGCTGCGCCTCCGGGTTCACGCGGAGCGGCGCGTAGCCGAGGCGGAACGCAGGCGCGCCGACGTCGGGCCCCGGCGCCCCGCCCTTCCCGGGCGCGGGCGGCGGCTTCGTGCGCCCGCGCAGGAGCAGCACCGAGACGAACGCGTTCGGCCGGAGGTCGTCCGTGATCGGCACGTCGATCACCGGCATGGCGCCCGACAGCCTCACCCGCCGGTGCGAGGCGATCCCGGCGCGCTCGACCGTGACCAGCGCGTCGGCGGAGGCGAACGGCGACTTCACGATCACGCGCGCCGTCTGCCCGACCTCGTAGCTGTCGCGGTCGGGCACGAGCTCGACCTGGAGCTGGTCGCTGTCGCCGAAGCCGCCGCCGCCCTCGCCGAGCGCGTAGACCCCGGCGGCGGCGCCGACGGGGTTGCCGCGGCGGTCCTTGGCCGTCGCGTGCATGAGGTAGTAGCCGCCGGACGGCACCGTGAGCTCGCAGCTCCGCGGCGCCGCCGCCGTCGTGACGCCGCAGCGCGCGACGACCTTGTCGACCGGCGCGCTCACGCTGCGGTACGCGCTGCCGCTCTCCTCGCGGGCGAGGGTCCACGTGCGCTGCACGAGCTCGACCCGGACGGCGACCTGCGCGACGCGCGCCCCCTTCGGATCGACGGCGAGGATCTCCGGCCGGAGCACGTCGCCCGCCTTCGCGAAGCGATCGGGCTCCTTGAGGGCGACGTAGAACTCGGCCGGGTGCACGAGCGCCGTCGAGCTCCCGGCGATCGCCTGCCGCGACACGTCCGTGATCTCCGCCTCGCACGTCACGGACTCGGTGCCGCGCTGCCCCGGCAGGGCGAGCGCCGCGCCGATCGCCGCCTGCCCGGCCGCGTCGAGCTTCTCGCGCCCGCTCTGCACCTCGAACTCGCGCGGCGCCCGGTCCGGCAGCGCGTCGGTGAGCTCGTCCTCGCGGACCGTGAACCCCTCGATCCCCGGCGGCGAGAACGCGGCCGGCGCGCGTGTCACCGAGAGCCGGGCCTCCGCGTTCGTCATCGGCGCCCCGAACAGGTAGTCGCCGCGCGCGATCCAGCGCGCCTTGTCGCCGCGCACGTAGCTCGGCCGGTCGCTCTCGACGCTCACCTTGAACTCGGCCGGGCGGTACTCGGCGACCTCGACGCTGCCGGTCACGTCCGGCCACCCCGCGTCGCCCCCCTGGACCGTGGCGGCGAGGCTGTACGTGCCGAGCCGCGCGGTCTCCGGGATCTTCACGTCGGCCGAGAAGGTGCCGAAGGCGCTGAGCGACGGCGACAGCGTGACGAGCGCCTCGCCGTCGGGCCCCTCGACCTTGAACGCGACGCGCCTGCCCGCCGGCGTCCTCGTCCCGCGCGCCGCCTCCTCGCGGAAGATCCCCTTCACGCGCACGGTGTCGCCCGGCCGGTAGATGCCGCGATCCGAGAACACCATCCCGAACGGGCGCGCCTCGCCGAAGTCGGACGGCGCGCCGAAGCGCCACCCGCTGAGCGCGTCGGCCACGCGGCGGTACGTCCAGTCGTCGCCCGAGCGCGCGAAGATCACGCCGCGCTCCGGCCCCGACGCGGTCGAGGGGCGGTACGCCGCCGCGGGGACGACCGCGAACCCGTCGGCGTCGGTGACCACCGCCGCGGGCGACCGCGCGTCCGGCGTCCGGATCCACACGCTGGCGCCGGGCACCGGCGCGCCCGTCGACAGGCGCGTCACCCACACGAGCGAGCCGTTCGGCGACACCTTCGCGCTGATCCCGAGGTCGGTCACCTGCGCGATCACCGCCTCGGACGCGGTGCGCGCGTGCCGCGTGCCGGGCCGGGCGGTGTAGCTGATCCCGATCGCGAGCGGCCCGCGCTTGCCCTCGCCGCCCAGCACCTCGCCGGCCCGCACGAGGTGCGTCGACGGCGTGTTCGTCGCGGCGGCCGGGCGCAGGACCGACCGCTTGCCGGCGGGCAGCGCCGCGATCTCGTCCATCTTGGGGCTGCGCCCCGGGCTGTGCGGATCGGCCTCCAGCGCGAGCACCGCCTCCTCGGTCATGGCGCCGACCGCGAGCGACAGCTCGCGCACGTTCACGGACACGACGGGGATCTCGCGGCGCTGCGCCGGCTCGAACACGCTCCCGGTGAGGCCGATCTGCGCCTCGGGCCAGCGGTCGCCGAACGCGACCTCCCGGGTGGCGGCGCCGGCGAGCGCCTGGCCGTGCTGGTCGCGCAGGCCGGCGGCGACGCGCACCTGGTAGCTGCGCCCCGGCGCGAAGGCGCCGCCGAGGTGGATGTGGCTCGTGAACGACTCGTCCTCCAGCCACCCGGGCCACCTCAGCTTGACGGCGGGCTCCACCGAGATCGCCCGCTTGGCGTCGGCGAGGCGGACGGGGTTCGAGAAGGCGAGCGAGAAGCCGCCTTCGGTCGCGCACGCCCCCTGCGGCGTGTCGCGATCGCAGTCGGTGCGCACCACCCGGAGCGGCCCGTAGGTGCGGTACGAGAACCGCTGCTCCTCGCCGGCCGGCAGCGGCCCTTCGCGGCCGCGGAGGCTCGCGGCCACGGCGAGCTCGACCTCGCTGTCGCGCGGCAGCGGCGCGCGCGGGACGATCTCGGCGAGCAGCTCGTTCTTCGGGTCGGGGCGCCGGACGTCGAACGCCACCTTGGCCGCGCGGCCGCCGGCCGTGAGGGACACGCTCCGCGCGACCTCGGCGGTGTCGACCGGCTGGTTGAACCGGAGCTCGAACCGCGCGTCCGGCCGGAGGTCGTCCTTGCCCGACCACGGCTCGACGCGCGCGACCTTGGGCAGCGCGGTGCGAAAAGAGAGCACGTACGGCTTCTCGAGCGCGCTGCCGTCGAGCGCGCGGGTGCCGGCCGGGACCTCGACGGTGAACGCGGTGCCGCGCGGCAGGTGCCCGTCGGGGGCGAACGTGAGGCCGCTCGTGCCGACCCAGCGCCAGCGCCCCGGCGCGGGCGGCTTGAGGATCGCGGGCGCGGCGGCCTCGCCGCCGGCGAGGTCGAGCGGCCGCATCGGCCGGTTGAAGACGAGGCTGATCTCGGCGGGGCTCGTCGTCTGCCCGCGGGGCGCGCCGAACACCACCGCGAAGGGGCCCTCCGCGGGCCTTCCGCCGGGGTCGAGCGCGCCGGGGGCGAGGGTCCCGCGGGGCGGGACGTTGGGGGCGCGCGCGCCCTGAACGCACGCCAGGCTGAGGGCGATGGCCGCCAGGGCGGCGGGCGCGAACCGGAGGCGCGAAACGGCGGACATGGCCCGCGACTCAGCAATGGTGGTGCCGCGGGCGCAAGGGGCATGTCGGCAGCGGAAGCCGGAGCGCGATGTGGCAGGCGAGACACACCCGACGAGCGGCGGTGACGCGCGGCCCCCCGCCCCGGCGTCCTCGACCGTGCCCTTCATCCGGGCTGCGCGGCCAGGCGGCGGTAGAGGTCGAGGCGCGCATTGGCCAGCTCGGCGCATGTCGTCTGCGCGCCTCGGTAACCCCCTTTGGACATGATGAGAACGCCGAAACAGCCGTGATAGGTTCATCTCTCTTGTTGACGACACCAGCGCGAAGAAGGGATCGGGAGCGATCTGCGGCTCCGTCGAGGCATCCCCTGAATTCTCGTTCGGCGCTCGTGCTCCTATTCGCGACCTTCGCGATCGCCTTCGGCGCGCCCGCCCCGGCGCTGGCGGACGAAGTGCCGGCGCAGGTCCTGGTCTTCCAGTCGGATGACCCGACCGCGCCGGCGATGTCCTCGATCACCGGCGAGCTCCGGGAATCGGTGCGGGTCGGGTGGGGCGGGCCGGTCACCTTCAAGCTCGAGTTCCTCGACCTGTCGTGGTTCGACACCCCCGATTACGCGCGCGAGCTCCGCCGCTTCTATCGGGCGAAATACAGCGGCTATCACCCCGGCGTGATCGTCGCGCTCCGGCTCGACGTGCTCCGGGTCGTGCTCGATCTGCGGCGCGAGCTGTGGTCCGGCGTGCCCGTGCTCTTCCTGAGCGAGGACCGGAGCGCCGCCCTCGCGGCGCCCGCCGCGCCGGACGTCACCGGGATCTGGCTCGATTACGCGTGGCTCCGGACGGCGGAGGGCGCGCTGCGCCTCCTCCCCGACACGCGAGAGGTCGCGCTCGTCATGGGCGCGAGCCCCTGGGAACGCGCGCGCCACGACGGGATCGCCCGCGATCTCGGCCCACTCACCGGCCGCGTCGCGCTCCTGGACCTCGCGAGCCTGCCGCTCGCCGAGCTCGATCGGCGCCTCGCCGCGCTCCCGGAGAACGCCATCGTCCTGTTCGACACGTTCTACATGGATGGCGCCGGGAACCGCTTCGTCGGGCTACAGGCCTTCGAGCGGATCCGAGCGCAGACCCAGCGCCCGTTCTTCTCCGTCCACGGGGTCGGGCTCGGCAAAGGGATCGTCGGCGGGGAGATCGTCGACTACGGGCGGGTCGGGCGCGACCTGGGCGGGATCACGCTGCGGCTCCTCGGCGGCGCGTCCGCGGCGTCGATCCCGATCCGCGCCGCGGACGCGAACGCGCTCGCCTTCGACGCGCGCGAGCTCGCCCTCTTCCGGATCCCCGAGGAACGCTTGCCGCCCGGCGCCGAGGTCCACTTCCGGGTGCCGTCCTTCTGGGATCTTTACCGCCGGTGGGCGGTGGGCGCCGCGGTCGCGGTCACGCTCCAGACCACCCTGATCGCCGCGCTCGTCATCGAGCGGCGGCGGCGCGGGCGCGCTCAGGCGATGAGCGACGCCGTGCTCGCCTCGATGGTCGGCTTCGTGGCGGTCGTGGACAGGACCGGGGTGATGCTCCGCACGAACCGGACGTGGGCGCGCGCGCCGCGCGAGGGCGCGCCGGGCCCGCTCGACCGTGTCGCCGAGGGGGAGAGCTACCTCGGCGCGTTCCAGCGGGCCGCGGCGGCGGGCGACGCCGACGCCGGGCGGGTCGTGGAGCTCGTGGAGGGGGTGCTCGCCGGGCGCGACGTCGAGGGCACGGCCGAGTACCGTCACGATGGCGCCGAGCGCTGGACCGAGGTGCGGGCGCGGCGGCTCTCGTGGAAGGACGGCGGGGCGGTCGTCTCCCACTTCGACGTGACCGGCCGGAAGCGCGCCGAGCGCCAGGCGCGCGAGTCGCTCAGCGCGCTCTCGCACCTCAACCGCGTGGCGGCGATGGGCGAGCTCGCGTCCTCGATCGCGCACGAGATCAACCAGCCGCTCTCCGCGGTGCTCACGAGCGCGCAGGCGGCGGAGATCCTGCTGCGCCGCGCGGCGCCGGACGTCGCGGAGGTGGGCGCTGCCCTCGAGGAGATCGTCGCCGGCGCCCGGCGGGCCGGCCAGGTGATCCGGCGGATGCGCGTGCTGCTGAAGAAGGGCGAGGCGCAGAGGGAACGGTGCGACCTCAACGAGGCGGCGCGCGAGGTGGCGCGGCTCGTGGGCAACGACGCGCTCCTGCGCGGGGCGACGATCGCGCTGGAGCTCGCGCCCGACCTGCCCGCGGTGCGGGGCGATGCGGTGCAGCTCCAGCAGGTGGTGCTGAACCTGATCTCGAACGCGCTCGACGCCGTCTCCGGGCGGCCGTACGGCGACCGCCGGGTGATCGTGAGGACGGCGCGCGCCGACGGGCGCGTGGCGCTCGCGGTGGAGGACTCGGGCGAGGGGGGCGCGATGGACGATCTCGAGCGGTTCTTCGAGCCGTTCTTCACGACGAAGTCGGAGGGCCTCGGCCTCGGGCTCTGCATCAGCCGGTCGATCGCGGACGCGCACGGCGGTCGGCTGTGGGCCGAGCGCGCGCCTGCGGGCGGCGTGGCTGCGCGCCTCGAGCTGCCGGGCGAGGCGGCGCAGGAGGAACGATGACGGGCGTGACGGCGAGGGTCGTGGTGATCGACGACGACGGCGCGGTGCTGCGGAGCGTGGGCCGGCTGCTCGGCGCCTCGGGCTACGAGGTGGAGCTGTTCGAGGGGGCGCGCGCGTTCCTCGCGTCCGCGGCGGCGGCGCCGGACGCGCGGGCCGGCTGCGTGATCGTGGACCTGGCGATGCCGGAGCTCGGCGGGCTCGACCTGCAGGCGGCGCTCAGGGCGTCCGGGTGCCGGCTGCCGCTCATCTTCATCACCGGACACGGGGACGTGCGCGCGTCGGTGCAGGCGATGAAGGAGGGCGCGGTCGACTTCCTGCTGAAGCCGCTCGAGGCGGACGAGGTCCTCGCGGCCGTGAGGCGCGCGATGGACCTCGACGCGCGGGCGCGGGCGGCGCGGGAGGAACAGGCGGCGCTCGCGGCGCGGCTCGACGCGCTCACGCCGCGCGAGCGGCAGGTGTGCGCCCGGATCGCGCGCGGGCAGCTGAACAAGCAGATCGCGGCGGAGCTGGGGCTCGCCGAGTCGACGGTGAAGCAGCACCGGGCGAGCGCGACGGCGAAGCTCGGGGTGGCGTCGGCGGCGGAGCTCGCGGCGCTGCTGGAGCGGAGCCGCGGGCCAGGCGGGTGAGCGCCGCGACGGGGAGGGTCTCTTGACCTGCGAGGTCTGGGCGAGGACCGAACGCCTGGAGAGCGGATGCGGCCTCGGGATCGACGATGTCGGCGGGCGCTGGATCCGGGCGTGACGAACAGCCCGCTTTCCTGAGCCCAAACGCAGGGCGACATCATGGGTGCCGTCGCGCGTCAAGTTGTCCGAAGGGACGATGGCGCGCACGCCTGCGCCGGCGTTAGGTACGTGGCCGCACGCTGCGGAGCGGTGATGACCCGCCTCGGCAAGAGCGCTCCAGACACCAGAGAGACCTCATGTACTTCGCGTCTCATGGCGCCGGGGCAGCTGCGTCGCGCCGGCTCGTGTGGTTCGCACACGTTCTTGACGTGCAGATGCCGGCGAACGCTGCCTGATCGATGATGTGGGTTGCACGACCCCGCGGGGCGCCCTCACCGCCCGAGTCGCTCGCGGCCGCCCGCGCGATAGGCGTCGACCCAGCTCCACAACGTCTCCAGCGGCACCCTCGCGCGCGCCGCGATCGCGCGCGGCGCCTCGTCTCCGCGGATCATCGCCAGCACGGCCGCCTCCCGCGCCTGCGCCCCGGGCGCAGCGCCTCCGGCCGGCGCCTCCGGCGGGGTACACCCCACCTCGGCAGGCGCGGGCGCCTCGGCGCGCAGCGCGAGCTGCTGGAGCGGCAGCCGCGCCGCCGGATCGCCGAGCAGCACGTAGCCGCGGAGATCGTTGCGCAGCATCCACAGGTGAGCGCGATCGGCGCGATCCGTGGGATCGGCGCGGCCCGCCGCGCGCGCGTCGGCCTCGCGCTGGTAGCTCTGCGCGAGATCGTCGTTCGCGCCGCGGTAGAACTCCATCAGCGCCTCCAGCGCGATCCCCGCGCGACTGCCGCGGACCAGCACCTCGAGCGGGCGATAGATACGGGACTTCTTGCTCTCCGACAGGCTCTTCGTCCCCGAGAAGCCGTACGTCCACGCGAGGTCGACGTGACCGATGACGGCGAGCGGCCCCGCCGGGTTGGCCAGCGCGGCCTGCGGCAGGGCCGCGACGAAGGGGCGGTTGCCGGATGCGGGGAGGCTGTGCAGCACGGCCCTCAGGCTGCCACCATAACGATCCTCCTGCGCGAGCTGCGAGAGCCATGCGTGGTAGACGCTCTCCGCCGGCGTGCCCGCGCCGAGGCAGGCCAGGTAGAACCACATGCCTCCCGGCAAGAACGCCTGGCCCCGCAGCCGCTCGGCGTCGAGGATCTCGTCGTGGGCGATCACGAGCGCCCCCTGGCGCCGCCAGGCGTCTTCCTCTCTGCGCCAGCCGCGCCGGGGCGCGCCCAGGCCGTGGCTCACCGAGAGCAACACCGAGGGACGCGCGCCGCCGCCCCCGGCGAGCAGATCGTCCACGCTGCCGGCGGAGATCTCGCGCACCGAGGCCGCGGGGAGCTTGCCCCTGGCGTGCGCTTCCATCGACGTGGCCAGGCTCGGGTCGACGAGCCTGAGCTTGCCCGCGACCGTGGCCGCCGAGCCGTCGGGCGCGGCGTAGAAGAGCAGCTCCGGCGAGGTCTCGGGCGTGCCGCGCCGCGCGTAGCGAACGACCTTCTCGGCGTAGGCGGCATAGCCGGCGAGATCCGTCTCTCCCGCGCCGTCCGCGAAGTGGACGCGCCCAACGAGCGCGTCATTGGCGAGCGCGTGCTGGAGCTCCACCGAGGTGTGATGGAGATCGCCGAGCATCATCAGGTAAAGGGGCCTGTCCTCCTCCGCCACCTCCTCGGACCAGTAGATATCTCTCCGGAAGTCCGCAGAGCGCTTGGCGTCCATCCCGTGCGGCACGCGAACCACGCGCGCGGGAGAGCCCTGCTCGGCCTCGCGCAGCGCGACGAGCGGCTGGACGGCCTCGAGCATCCGGTCGCCCTCCCGGCCCTCCGGCGCGATCACCGCCCATCGCTGGAGGGTGAGGTCGTTGCGATCGGCGTCGGTGCGGCGCCAGTGGTTGGCGTCGCGGGCCTTCCTGGGCCTCGGCGCGCGCTGGGCGGTGTCGTCGGGCAGCCCCTCGTCGAGCACGGGGCGGCGCTCGTCGGCGTCGGCGAGCAGGAGGTCCAGCCGGTCCTCGCGGAGGATCATGGTCAATGGATCCTCGGGTGTGTCACGAGGCGTCCTCCAGCGCGAAGGCGTCGAGCTGCTCCGCGAGCTCCACCAGATCTCCGGTGGTGGCCGCGATGTGGCCCGTGCCGGGCAGCCCGCCGCCGTTGCCCCAGATCTCGATCTCGCTCCCTTCGACCCCAGGCGCGAGGACGGCCAGGCTGTCCGGGGGCGCCGGGCGTTGATCGTAGAGCCAGCGCAGCAGCATGCGGTGGCGGAAGTCGAGGCTCGAGAGCGCGACGAAGAGGCCGGGCTGGACGCGCGGCCGCGCCAGGAGCTCCTCCATCCATAGCGGCGGCCGGGCGCCGTCAGCGCCGAGGGGGCCGTGGATGTGATCGTCCTCGGTGAGCAGCGGCGGCGAGAAGATGGGGCGCGGCTCGGCCGAGTAGCCGCCGTACAGGCGGAGCACGACGATCTCGCTGTCGAGATCGAAGCGCCTGGGCATGACGGCATCCATCTTCCACGTAGCCGTCCCCGCGGCGCGCTTGACGACGCGCGGCTTGCCGGAAGCGCCCAGGAGGGACGGCTGGATGGCGTACACGGTCCGCTGCGGCAGCTTCTGCGCGATCGCGTGCTCGAGGCAGGGCCGCCAGAGCAGCGTGACGTGGACCCCCGGCCGGACGAAGCGCGCGAGCGCCTCGACGAGCGGCGGGGCCGTCGCCGCGGGAGAAGCGGTCAGCGCCTGCTGGAAGAGCGAGTGCAGCACCTCCTGCCCGAACCGGAGCACGCAGCGCTGGGTGAGCGCGCTCAGCGACATCCCCTGCGCCGCCGGCTCGCCGCTCTCCTGCATGAACTGCTCGAGCTCCCGCTGGAGCGCCGCGCGATCGTCCTCGAGATCGCCGAGCACCATCGTGAACGGCCGCTCGAGCAGGCTCTGGAGCGCGGGCGCGAGCGCCCTCGATCGGCCCTTCTTCCCCGGCCTCGCCACGCGGCGGCCCTGGAAGTTGAAGACCACCGAGTCCGAGCCGCGGAGGTACAGGATCGGCGAGAACGCCTCGGCGCTCTGGGACAGCAGCGTCCGCCGCGCCGCCGCCACGCTCGCGCCGATGTCGCCCTGGCCCAGCGAGGCGCCCGTGAGCGCGCGGTAGAGCTCGGTCGAGCACGCGCGCGCCACGTCGGCCTTCACCGGCCAGAGGTGCGCCACCACGGCGTCCGCGCCCGCCCTGACCAGGATCTCCGCCGCGCTGCCGAGCGCGCCGGCCCGGGCGCCCTCGCAGGCCTCGAGGATCACGAGGCGCAGCTCCTCGCAGAAGGCGGCGGAGAGCTCGCGGCCCAGCGCCTCCGCGGTGATCCAGGCCTCCTCGCCGTCCTCGTCGTCCGAGACGCGCAGGACGGGCTTGCCCGAGAGATCCACGCCGCCGTGGCCGAGCCAGTGCACGACGTGCGGGCTCTTGCCGCGACGGAGCCGATCGAAGAGGGCCCGCGCGCCGATGTCCGGCCCGGCGATCGGATCGAGCCACTCCACCTCGCCGGCGTCGATCGACGGAGCGAGCGCCTCGCGCAGCACGTCGAGGGCCCGCTCGCCGGTGCCCGGCGCGATCCCGAGCACCCGGACCGCGCCCTTGACCTCGCGCGGCTCCCACGGCTCCGACGAGGTGACGCCGCGCGCGAAGAGCACCCGGGGGTCGGTCCCCAAAAACCCTTCGGAGGTCCCCGGCCTGCAGAGCGCCTCCCAGGGGATGGCCTGGAGCGCGTGATCGCGGGCGAAGAGCCGCAAGAGGAGCGGACCGCCCTTCGACGCCTCGCCGAGCCGCACGAGGACGTCGCGCAGCTCCCCTTTGAAGACCTCCTCGTGGAGCGCCTGCGAGTCGCTCACCGCCGCTGGATCGAGCGATTTGCCGCCGCGGACCGCCCTCCCGATCTTGTTGGCGAAGGTCTGCAGGGCTCCGAGGCCCTGCTCGGCGGCTATCGCGTGCCCCGCGGGGCGCTCTCCCCGGCTGCCACGCGCGTTGACGCGCACCTCATCACCGCTGATGTCGAGCTCGATCTCCAACCACATCGAAAGACAAGCCTCGCTACGTTGTGCTGCCTGCCATGTCTGACTCCGTGGCTTTGTAGACCGCAGCAGGAGGAATTCTCACCTTAAAAACGATTAAGATCGCATCGGCGGGAACGTCCTTGGGACGTGATTAATGATGTGTGCCGGCAGGCGTGCGCGACTGAGGAACGGACACCATCATGGAACTCACGGACGATTCTCGCTCACGATGGCTCGGCAGATATGAGGCCCTGCGCGCCATCCGCCGTCGCGACGGCTTCCACGTCGTCGCGGCGACGCGCGCCGGGGACGCGGAGCCCTGCGTGGTCATCGTGCCCGGCCCGGCCGTCAGCGCGGCGCGGGCGAAGACGGTATTCGCCGAGATCGAGCGCGTCCACGCGCTCCTCGATCACCCGCTCATCCCGAAGGTCGCGGCGCGCGGCGTCGCCGACGGCATGCCGTACATCGAGCTCGCCTGTGACGCCGTGATCGACGGCGTCGACCTCACGAGCCTCCTGAACGACGCCGGCTGGAGGTTGCCGCCCGGGAGCGCGGCCGGCCTCGTCGCGAGCCTCCGCAAGGCGATGCGGGCGGCCCACGCGGTGATCGATCCGAAGCACGGGCGGCCCGTCTGCATCGGTCGCGTCTCGTGTGCTGACGTCCTCTTCTCCCGCGAAGGGCGCTTCTATCTCGTCGGCTACGGCAGGGATGCCCCGCTCGAGAGGGCCGGAGGACAAGAGATCGACAGGGTCCTGGAGTTCCAGGCGCCCGAGGTGGCGGCCGGCGGCGACCCGACCCCGGCGGGCGACGAGCTCGCGCTGTCGCTCCTCGCGCGGTCGCTCCGCCATGCGGTCCAGGGCAGCGCGGCGAGCGCGCGCGGCGCCGACCGGAACATCCGCTCGATGGACCTCGAGCCGCCCGAGCCGCTGGAGCGGCGCGCCCCTTTCGCGCCGGCGCACGCGCGAAGGTGCGCCGAGGAGATGGACCTCCGCCACCACCTCGCGCCCTGCAGCGAGGCGCCGGATCCCGAGGGGTTCGCGTCGCTCGTGGCCAGCTTGCTCGCCGGGCGGCCGCTGCCGCTCGCCGCGGAGGCGGCGCCGACCTGCCCGCCCACGCTGGTCCTCGGCTGCGAGGTGCGCTGGATCACGGCGGAGGACGGCGTGAAGCACACGCTCGGGCACGCGCTCAGCCGCATCGTGACCGCCCTCGTCGACCGGCACGACGAGGCGCCGGACGCCGCGCTCTCGCTCCAGGACCTGTTCGAGGCCGGCTGGCCCGGCGAGCGGCCGGTGGCGAACGCGGGGGCCAACCGCGTCTACGTGGCCCTGACCCAGCTCCGCCGCATGGGGCTCAGGGACGTTATCGAGCGCAACGAGCACGGCTATCGCCTCGCGCCGCGCGCCGTGGTCCGGTTCGTCTCGCCTCGGACGGAGCACGCGCGACCTCAGGACACGCGCTCTGCCCCGTGACGGGCGCGGCGCGCCCGCCGCCGCCGCTACCTCGCCCTCTGCTCCCCGGCGAACGTCTCCGCCACCTTGAGCACGAGCCGCTCGCTGAAGCCAGCGATGAACGCGATCGCGAAGGCCTTGCTGTTGTCGGCGTCCCCGAGGTTCAGCACCCTCGACTGGAGGAACGCGTAGGCGGCGAGCCCCGGCAGCGCCCCGAGGACGGCGCGCGAGAGGGTGACCCGCGCGTCCGACACCCGCGCGTGAGCCCTGGCCCGGCGGGAAGAGCCCTTGAGCGATCGAGCGGCGCTGAAGGTGGCTCCCAGGGCGCCAAAGGAGAAGACGCCGAGGAGGGTCCGAGTTCCCCAGGCAGGCCATTGTTGGACGGGAGCTCGCGCCGTGGCCGTGAGCGCCACGAGGAGCAGCAGGACGAGGAGGGCGAGCAGCGCGAGCGTCCAGAGCTGCTCCCGGAGGAGCCGGCTGCTGGTGTCGACGCCGGCGACGCGATCGCGCCGGCGCGACCGCAGGGCGAGGCGCCGCCGGGCCCTGCGTGGCGGCGCCTCGCCCGCGGCCTCGGCGGGGGGGCGGGCCGGCGGGGCGTCGGGCTCCTCTTCGGGCGTGCGCACCGCTACGGCAGCTCGCCCAGCGCCGCGAGCCCGGCCTCGCAATAGGCGTCGTACCAGCGCTGGAGCTCTTCGCGCGTGATACCGTATCTCTCGGCGATCTTCCTGTCGCCCTCCTCCCCGAGGATCTTCTCGTGGACGGCGCGCTGCATGCGCGCCGCGTCCCGCGCGCGCCCCGCCGCCGGGGCCGGCGGCGCGGCGGGCAGCTGCGGGACGGGCGAGCGCACCTCCGCCGGCGCGGGCGTAGCCTTGACGGCTCTAATGTCGCGGTCGATCGCGAGCCGCGCCGCCGGATCCCCCAGGAGGACGTACCCCGCGAGATCCTCGCGCAGCATCCACAGGTTCGCCCGCCGCTTCGCGCGGCCCTGGTCGGGGGCGAGCGGCTTGCCCGCCGTCTCGGCCCTCGCCTCCTGGTTGTACATCGCGGCGAGCTCGTGGTTGGCGTTCCCCAGATAGCGGAGGAGCTCGTTGTACGAGTTGCCCACGCGGGCGCCCTTGACCAGCGAGCTGAAGACGCCCTCGAACCGCGACGCCCTGTCCTTGCCGTCGGGCCCCATGTCCTGGAAGCTGTAGGTCCAGGCCAGATCGATGTGGGCCATGACCGCGAGCGGGCCGCGCGGGCTCGCCAGCGCGGCCTGCGGCAGCGCGGCGATGAAGGGCCGATCGCCCGGCCTGGGGAGGCCGGCGAGCACGCCGTCGACCCGCCCGCCGAAGCCGCCCGCGTCGCGCAGGCGGGCGAGCCAGTGGTGATAGGCGCTCGCCGCCGGCGTCCCGCCGCCATAACACGCGAGGAAGAACCAGATCCCGCCGGGCAGAAAGGGCCTGTCGCCGAGGTCCTCGGCCGCGATGCGCACGCCGGAGCCCAGGCTCATCGCCCCTTGCACGGCGCGCTGCTCGTCCGCCGACGTCCATCCCCTGCGGGGCGCGCCCAGGCCGTGGCTCATGGTGAACAGCATCGACGGCTCCGGCCGCCCGAGCTGCTCGAGGAGCGCGCTCCTCGCCGCCTCGGCGCCGTCAAACCCGATCTCCTCGATGTCCCTCGCCTTGAAGCCGCCCCTCTGCCGGGTGTCGCGGCACCGCGCCACGCTGGGCGCGACGAGCGCCCTGTGGCCGATGGTGGTCGCCGCGGTGCCGTCCTGCGCGGTGAAGAAGAGCGCCCGCGCCCGCGCCTCCCTCGGAGGGGCGCGCTCCGAGGAGAGGAGCTTGTCCACGTACGCCGCGTAGCCCGCGGCGGACCGGGACACCAGGCGACCGACGAGCGCCTCGCTCGCCATGGCCTGCTGGAGCTCGAGCGAGACCTCGTCGAGGTCGCCCAGCACGAGCAGATACCGCGGCAGGTCCTCGAGCGCGACCGACTCGTCATGATAGACGCTCTTGCTCCACCGGATCGCCGCGTCCGCGTCCATGCCGGCGGGGACGCGATAGGGCACGACGGGCGCGCCCTGGTCCTGCTCCCGCTTCCGGATCAGAGGCTCGACGAGCGCGAGGAGGGCGTCGCCCGCCGGCCCCTCGGGCGCGATGACGGACCAGCGCTGGAGCGAGAGGTCGTTGGGATCGTCGGAGAAGTCGGCGAAATCGTGGATCAGCTCCTCTCCGCCGGGCTGCGGCTCGTCCGCGGCGGACTCGAGCGGCAACCCCTCTTCGAGGACGGGTCGATGATCGTCGGCGTGGCACAGGAGCAGCTCGATGTCGGACATCACGCCTCCCTCCCAGGCGCCGCGCCCCCCGGGGGCACGCGCGCGGCCTCCAGGGAGCGGAGCTCTCCATCGTCCCATTGAACGAGCCGCATCGTCGCGCCGCCGTCCGGGTGCGGGTCGACGAGCACGGCGGTGAGGCGCCGGACGGTCTTCGCCGCCCGCTGCCGCTCGGGCAGGAGCCTCGGGTTGTTGCGCAGCTCTTCGAGGAACTCGGCCCACGCCTCGTCTCCGGCGTCCGAGCGCGGCAGCTGCATCAGCCAGATCCACGTGCCCGTGTTGGCGAAGGCGATGCCGTCGGCCACCTTCCAGCGGGCCGCGTGGGTGTGGCCGAGCACCACCGCGCCGGCGTCGAACTTCTTCGCCAGGCGCCGGGCGTCGGCCCACTCGGCCTCATCGGGCTCGAGGCGGAAGTACTCGTCGCCGAGGGTGCCTGCGAGCCTCTTCTGCATGCCCGCGTAGAGCTTCAGCCCGGCGCGCGCGAGCTTGAGGCTCGCGGTCGACATCGTCTCTTCATCGGCGAACGCCGCGGGCCCGTCGCCGAGCGCGGCCTCGATCGCCGCCGCCTCCTCGGCCTCGAGGCCCGCGTCGGCGAACCGCTCGGCGAGCCCGAGATCCTCGTCCTCCTCGGCGAAGGAGGCCGCCGACCCCGCCTTCTTGAAGAGCTGCCAGGCGATGTCGAGCGAGGCCGCGCTGAAGAGCTGCTTCACGATCCCTGGCGCGACCGCGAGCGCGGCGAGCGCCGCGCCCTGGAAATCGGGCTTGAGCAGGCTCACGAAGCGCATGCCGTGCCGGCGCGCGATGGGGTTCATGAGCTGCTTCACGAGGACCGAGCCGGCCGCGTACCTGAACCGATCGAGCCGGGCCAGGCGCCCATAGTCGACCTTGTTCCAGTTGTCGTTGTGCTCGCCGTGGGTGACGAGGATCCGGGCGCCGCCGACGTCGAGGATCGCGGGGGCGTCGCCGAGCTGGAACGTGAGGCGCGCCGCGACCTCGGGCGGCTGATCCATCGCCGCGCGCAGGATCTCCTGCACCTCCGGGACGGCGAGCTCCACGTCGTGGTTGCCGAGGCGGACGATGACCTCGCCGCCGCGCGCGAGGACGCGCCCGAACGCCTCCAGCACGGCGGCGCTCGCGGGCGCGGCGGCGATCGCGCGGGCCTGCGCGGCGGCGCGCGCCGGATCGAGCTCCAGCGGGTCTTCGTTCATGAGGAAGTCGACGCCATCGCCGTTGACCACGACCCGCGCGGGCTCTCCCGCGATCCGGTCGAGGAGCGCGGGCAGCGCCTCTCCCCCGGCGAAGACGTCGTAGTCACCCCCGTTGCCGAGGTGCAGATCACTGATGATGAGGGTACGCATGAGGGTTGTCTCCCGGGTTGCTGGGGCGCCCGCCGCCGCGGCTCAGCGGAGCGCCGCGGGCGCCGCCCAGATCGCCTGGTGAGGGCGGTTGTGCAGGCCCTGGGCCGGGCTCCACGACATCTTCGCGTTGCCCTTTGCATCGCAGAAGACGTCGAGCAGCGGCCGGTTGTCCGGGGCGAGCTTGGTCGGCGCGTCGGACTTCGAGTTGACGCACCACGTGGGCTCGATGCGGTCGTGGAAGGGCGCGCCGCGCAGCGAACGGAGCAGCCAGGAGATGGGGAGGCCCTCGTCCTCCATCGACATCCACTCCGAGCGATAGAGCAGCGCGCCGTCGCCGCGGCGCCGGAGGAGCAGGCGGGCGCGCCCGCGCGGCTTCAGATCGCTCTTGATCTCTCCGAGGCCGTCGATCCGGGCGATCCCGCGGAACGACCACCGACCGCCGCAGAGCGCCGGCGGGATGAACGGCCACCAGTGCGACTCCCAGAGCATGCGCGCGCCCCTTCCGGCGGCGGCGTGCACCGCGGGGTCGTTGAACGACGTGGTGGTGTCCCAGAGCTGCCATTTGCGCTCGACCGGGTGCTTGCGGATCACCATCGCCACGTGGCCGCTCCCGGCGCCCGCGGCTCCGGACGCCGACCAGAAGAGGCACGAGCCGACCGTGACCTTCTCCCAGAGGTCGTCGGGCCAGTCGGCGAGCACCTTCGGGACGGAGGTCCAGCCGTCGCCCAGCCTGGCTGCAGCCGGCAGCGCGTCGGTCCCGCAGCCGATGTCGCCGTACGGGCCGCCGTCCCAGCCGCCGATGCAGAGCGCGGTCGTCACCGACTGCTGGCACTGCCCCACGATCGGGTACCGCCCGCTGCCCGAGATCGCCTTCGCGACCCCTCTTTGCCCGCCGTAGAAGAAGGCTGGCATCGTGTACGGAATGCCGGTCTGGTGCTCGGCGATGGCCCGCGCCCAGTCCTCGCGGTCGCCGGAGGCGGTGTCGTAATCGGGGTGCGAGAAGACGTCGCCGATCCCTTCCCTGGCGCGGGACAGGAGGAACGCGGCGAGGCCCTCGGCGTCCTCGGGCCCGCGCAGGCCGTGCTCGGGCGGGTCCAGCAGGTTCACGGTGCGGACGAGCTGCGGTGGCGGCTCGTCGTCGGCGAACGCGACCGGGCGCGCCAGCCACTCCTCGGGCGGCTCGGCGGGCGCCGGGTCCATGTCCACCCACGCGGGGACGCCCGCCAGCGGCGGGGCTCCGTCATCGCTCTTCTCTGCGGTCATCGGTGCTCCTCCTCTTCTCTTCGATTCGATGTCTCCGCGGCTGCCGCCCGGGTCGCCGCGCTCGCGGCGAGGGCCGCGTCGAGGGCCGCGAGCGTCGCCGCGCCGATCACGCCGTCTGCGGCGAGGCCGCGCTCGGCCTGAAACTGCTTGACGGCCGCCTCGAGGCCCGGGCCGAACGCGCCGTCGGCGCCGCCAGGCACGCTCTCGCCCAGCGCGATCAACGCCTCCTGCAGCGCCTTCACCCCTGATCCCCTCGCCCCTCTCCGGAGCGCGCCTCGACCCGAGGCGACGCTCTCCAGATCGGGTTGCCCGGCGAGGGCGGCGCGCGTGAGGCGCGGATCCTTCGGCGGGCTCGGCGCCTCCGGCGGGGGCGCCGCCGCGGGCGCGCCCATCGCGGCGGCGAACGGGTCATCCCCCGGAGGCCCCGCGGCCTGGAGGAAGGGCTCGTCCAGGCAATCGAGCCCGTCGTCCTTCATGTGCCGGAAGTAGAGCCGGAACTGCCTGAAGTCCGGGATCCACCTGTGCTTGCGCGCCTTGCCGTAGAAGTAGCGGCCCACGAGCGCGGCGAGGCGCCGGTCGCGCTCCTCCGAGGGCGACCCGGGGCCGAGCTGCGGTACGGCCCACTCGAGACACCCGATCACGTACCCGGGCGCCCAGTGCTTGAGGTGCGCGATCAGGTTGAACAGCGCCTGCGTCGCGATCGCGTCGGCGCCGCAGATGTTGCCCGAGCCATCCATGAACGTGCGGAGCTGGGCCTCGGTCACCGCGTCGCGCGTGGCTGGGTTCCTGGCCAGGTCGATCAGCAGGTGGAGGAGCGGGACGGAGCGGCGCAGGATCTCGAGCGCTTCCTCGCCTCCGGTGACGACCGTGCCGGCGTCGAGATCGACGACGTCGTACACGTTGCTGCCGCGGTAGCGGACGCCGGCGGCGCCCAGCGCCTCGCGCACGGCGTCGTTCGCGGTCGCCCGCTCCATCACCTTGCCCAGCCAGCCGCGGCCGCCCCAGCCCGTCCCCCAGGTGACGATCTGGTCATCGTAGGTGTTGATGGCGGCGGTGCTGCCCTCGCGCGCCTGGAGCGCGCGAAAGGCCATGATCTTCCGCCGATCGGCGGCGCTCGCCCTCGCCGCCCGGGCGTCGATATACCCGTGCAGGTAGGCGAGGTGAGCCTTGTCCGCGCTGCCTGTGTAGACGTGCCCTGCGCCCCAGGGCTTGAGCCCCGGCTCGACCGGCACGGCGGCGCGGCGCTGCGCGATCTCGGCGGTGAGCTCCTCGGGCAGCGCGCTCCCCGCCTCCGCCGCGCCCGAGCCGCGCGCGTGATCCTCCCAGACCGGGAGATCGCCGTCCGCGAACGAGAGGGCCCCGCCCGGACCTCCCCTGGCCCGGGCGGGCTCGGGGCCGGGCGCGGGGAGCGTCAGGTCAGCGTACGCGGCGGAGGATCGGAGCTCGGCCACGCCCGCGAGCGACGTCTGGATCTGCTCGAGCAGCGCGGCGTGGAGCTCCGCGCGCCGGGCCTCCTCGATCTCGTCGAGGCCGATCTCCCACGTGTACGACGCGCCCTTCCCGCGCAGGATCCGGTGCGCGAAGAGCGCCGGATCGAGCGTGGGAAAGGCTCCTAGCGCGAAGGCCGAGGCGCGCGAGAGCAGGGCTCGCTCGACCTCCTCCGCGTCGCCGCGCGTGACGGCGAGCTCGAACAGGAAGACGTTCCGTGACATGGCAGGTCCCTTTCGGCGGTGACGTCTCCGTATGAAACCGACGAGACCTGGCGTCGTCATCTTAAGAGAAATTAAACGGGGTGTTCCTTCATGCTCCGTCAGCCCGGCGAGGCCGCCGCGCGGCGCGCGTCGAGGAGCGCGGCGCGGTGCTTCACCGAGCCGGCGACAGCGAAGGTCGGCTCCCAGGCGAGCGACTTGTCCCACGCGTTCGCCCGCGCCCGTTCGAGCTGGTAGGAGGTGGTCACGCGGTCCTCCCGCTGCTTCACGAGCTCCTCCTTCATCCTGCCGCTCTCGTCCTTCGGAATCGAAAGCTGCCCCGTCTCCGGGTCGATCTCGCCCTTGCGGAAGTAGATGACCATCCGGATCTCGTCGACCACGGGGCCGTCCTGCTTCTTGCCGACCTTCTCGCGCACCTCCTGGGCCTTGAGCACCAGGAGCAGCGCCAGGCTCTCCACCGAGTAAAAGATGCTCGGGCTCCGGACGCCGTACAGCGTGTGGACGCGGACCGTCCCCCGGGCGTTTCCGGCAAAGGCGCGCGACAGCTCGTTCCACAGCTTGTCCGCCTCGGGCGCATAGTCGATCCCGTTCCCCGAGAAATTGATGCTGTCGAGGAGCTCCCCGGCGATGGTCATCTCCACCGAAGCCGCGTCCAGATTGCCAGCCTGACTCTCGGCCTCGGCGGCCCGCCGGGCGGCGGCCTGAGCGGCCTTGTAATCGACCCCGCCCGTCCACAGGTGGGTGCCCGCGCCGCCCGAGATCCCCTTCTGCGGGGCCCCGCTCCCGGCCCGCAGCTGCGGGTTCGTGGCGTCGATCCTCGCCGCGAGCTCCTTGGCCATCTGCTCGAGGCGATCGTCGAAGACGCCCTTGTCCGCGGGCGTGGCGTCCGCCTTGGCGACCACCTGCTCGATGAACCGGCGCGCCCAGTCGATGACCCAGCGGAGCTCCAGGCCGGGATAGCGCTCCTCCAGGGCGGCGACCCGCTCCGAGAGGCGAAGGTGGGCCGGGTGGGTCTCCCAGTCGAGCTTCGGCGGCGCAGCCTTCCCGGCGGAGGCTGGCAGCGCGGCCGCGAGGGCGGAGGCCGCCTCGAGCAGCCGCTCGGCCCCCTCCGCCGGCTTTTGCGCCAGCGCCTCGGACGCGGCCGTGTCGACCCTCTGCGCTCCGGCCGGCGGCGCGGTCGAGCGCGGCGCCGGCGCGGCGCCCGCCCGAGCCGCGAACAGATCGGCCCCGAACGCCCGCTCCAGAGAGGCGCGCACCGGCTCGGCCGGCGGTCGGGTCGGCGGCGGCGCCCTCCGCGGCAGGTGCATCGGCGCCGGAGGGCGCGCCCGCGACGTGCGGGCGGCGTTCCCCGAGGCCTTCGGAGCGGACCGGTCAACGACGATTTGCATGAGACTCTCCTCGGCGCGGGCGGAGAAACGAGGCGGCCCCGCGCGTCACCGCCCATCCTGCGATCAACGAAGCCGCGGTCGCGCCTCTGCGAATCGAGAACGAGCGCTCGGAGCGCAGCCGGATGCTGGTCGAGCCGTCGTGCATGAGGGAGAGCGGCGAACGGCTGCGGCGTCGTCCCTTCACGTCAGGTTGTAACGGCGGTACGCTTCGACCTCATTGACGATAGCATAAAAGCACTCGTCAAAATTCTGTGTCTTCAGTTCAGTCACGATCTTCAGCGCAGCCGCATAGGAATCGGCTTTCAGCTGATCGGCCGCGGCCGCCCCCACGGTCGGGTACTGCTGCGACTTGACTTGGAGATCAATCTCCAAATCCGTCAAGAACTTTGCGAGGTTTGCTTGTATGAAGTTATGATCCAGCGCTGCCCCAGCGTTCAGATCCCTGATCATATCGTTCTTGAAACTTGTCATCTGGCGGTCGATGATCTTGTCCGAGGTGACGTTAGCAATCTGGAACTGGGGCGTCGTCGCTGCAGTGGCACGATACAAGTCGTCGAGATTTTCCTGGTCTCTCGGCGTCAATGGCAAGCCACTGAACAACGACTTTACAAGCGTGACGTTCGTCAAATGCGCGGCGTCGTATTTGCCTTCACCCGGCGATGCTGTGGCAGCGTTCTTGATTCGGAATCCGATGCCCGCCTGAGCCGCGGCGTTATTGGTGAAAAGATTAGGGAGGGCACCCTGCGACGCACACTTCCGCCACAGAAGAACGGCTTTCAGAAATACGGTAAAAAAGTGTGTCACCCGCAGGGCAACATGGCTCTTGTAGTTGTCCATGCTCGGGCGCACGGTGGCGACGTCACCAGGATCGATCTGATCGCGCTTCATCCGTTGGACCACAGCGCTCGATCCACGCAGCGGCTCCGAAGGCGTCTCGGGCGCCCTCGCCATCGCTCGAGGCAAGCCGGCGCTCGTATGGGCCGCCCGCGCCCCCATCGCGTCCGCCTCCGCCTCCAGCGCCGGCGCGTCGTTGAGCTTGATCCCCTTGTACTGCGCCGTCGCCTGCACGCGCCCCGCCCGCTGCTGCACCACGTGCGCGAGCTCGTGCCCGAGCAGCTCCTGGCCCCGCGTCGTCTCCGGCGCCCACTGGCCCGGCGCCACGTGGATCTCGCTCCCCTGCGTGTACGCGAGCGCTCCCAGCGCCGCCGCGCGCGAGGAGCTCGGGTGCACCCGCACGCCGGAGAAGTCGGTCCCGAACGCCGCCTCCATCTTGGCCTTCACCGGCGACGGGATCCCCGTGAGGTTGACGGCGCGGTCCGGTCCGCTCCCGCCCCCCACGCTGGGCCCAGCGGCCGCGCCCGCAAAGAGCTCAGCCCCGAACGCGCGCTCCAGCGCCGCGCGCCCCGGCGCGGCCGGCGGTCGCGCCGGCGTCATCGTCCTACTCTGCGCGAGCAGCGGCGCCGGGCGGCGGGCCCGCGACGCGCGCGCGGCGCTCCGCGAGGTCTTCGGAGTGGACCGGTGAACAGCGATTTGCATGAGACTCTCCTAGGCGCGGGAGAAGGGCGAGGCGGCCCCGCGCGTCACCGCCAATCCTGCGATCAACGAAGCCGCGGTCACCACTCCACAGAGAGCGGCGCCTCCATCCAGGGCTGCTTCACCCAGCTCATCCCCCAGGGAAACCGATCCAGCACCACGTCGTACGAGGCACGCTCCACGCGGAGGTGCCACGCGCCGTCACGGGCAGAGAGCGCGCCCTTGCGAACCAAGAACGAGCCACGGAATCCGGCGATCGACATCTCCCCCAGGATCGGCGCGCTCGCGATCGCCGCCGTGAGCATGCGGACGCACTCCTCGGCCTCTGCCTCGGTGACCGGAGGACCGAAGTCGAAGACCTCTGTCATTCGCATGCCAGAGAGCACGCGGGCCAGGGGAAGCTGGTACTCGGCCGGCTCGAGCTCCCCGGTGCAGAGGTGCTGGAGCAGGCCGGCCGCGCGGTGGAGGGCGCGTCGATCCTTGAACTGCGTGTCGGCAAAGAGGCCCAGGCGCTCGAACAGGTGCCCGAGAAAGGGCCAGAGCACCACCAGCCCGGCGTTGTCCACGTAGACCTCGTCGGCGTCGCCGTGCGCTGGATCGACGGACAGCGCCTCGTCCGCGGCCGTGGCCCCCGGATCGCTCGACGGATCCCCTCCCCGCGCCTCCCGGACCGACCTCTCCGCGACCGCGCCAGGGCGCTGCCCGACCGCGCTTGAGACGGCTGCGCCAGGGCTCTGCACGACCTCCGCGAGCGCGCCCGGCCAGGCCGATGGATTCGGCCCCAGCGGCGCGTGCAGCCCCGCGAGGAGAGACCCGAGGGACACGCCGGCCTCCAGCGCGATCCGGGCCAGCGCGTCGCGAAAGAAGCCCACCCGCCCGTCGCTGGGGCTCTCCTCGAGGCACGCAGTCCGCAGCGCGCCCGTCCAGACGCACGCCCGGAAGCCGTCCGGCGTGGCCCCAGCGACCGCCCGGTGCGCGCGCAGCAGGGCGACGAGCTCCACCGGCACCGAAGGGAGGTCGGCTCGCGAGGACGCCACGAGAGCGTCGAACAGCGCCCAGAGCTGCGCGTCGCGGCTATGGCGGACGATCCTCGCCAGCGCGCCGCCTTCGCGCGCGAGCGCCCTGATCAACGCCACGAGCGGGCGCGCCGCGCGCTCGAGGAGCAGCCCCAGGGTCTCGTCCAGGAGCCGCGGTCGCGTGCTGTCCGCCCACCAGGGGAGGTTGCCGGTGCGGGCGAAGGACGCCACGAGCTCCAGCCGCGAGATCACCTCGGGATCTCCGCCCCGGAGCGCGGTCTCCTCGTCCTCCTCGCGGAGCCGCGCGGCCAGCCCCTCGCGCAGCAGCGGGCCGAGCTTGTCGACCAGATCGCGCTCCAGGTGGTCGGGATCGATCTGCCCGAGATCCACCTCGACCCGCGCGACCCGCTGGAGGCGGTCTGGAGCGCCGAGCTCGGTGCAACACCGATCGATGACCGCCTCGAGGCGCTGGGTGTGGATGCGGCCCAGCTCGGTTTGCAGCCGCCACGCCGCCTCGCGATCCTGGACCGTCACCTCCAGGATCTGCCGACGGATCTGGTGGCGCGGCGCGCTCACGGCTCTGTCGCCGCGGGTTCGGGGGCAGCGCCCTGCTCGCTGGGCGAGCTCCCATCGGTGACCTGGGTGATCGCCACCGATCGCTTGGCGACCCACCCGATCCCGGTGCGGGCCTTGATGGCCATCACGTCGACCGCGCCGCCGAGGGGCAGCGGCGCGATGTCCACCAGGGGATCGAGCGGGCGCACGTGCGCCGGATCCAGGGCCGCAGGCGCCGGCGGATCGCGCGTCACCACGAGATCCATCTCGACCCGGAGCCCCCGGCGCGGCACCTGGTCTGCCGCTTCCGGCTCGGTCGCCGCGACGCCCTTGTTCATCGACGGGTCCCGCTCGTCGCGCCGGTGGAAATACGCCGGCAGGCCGAGCGCGCCGGCCTCGTTGCTCGGGTAGAAGTGGTAGAAGACCCCGGGCTGGCCGCCCGAGACGAGCAGCGTGCCGCTCGCGTTGTCAGCGTTCGGCGCGATTTGCAGCACGAGCGGGGGCGCCGGCTCCGGCCTCACCAGGACGACCGCCGCCTGCTCGAGCTGCACCGCAGACTCGAGCGGCGCGCCGGCCGCCGTGTGGATCTTGCGCGCCTGCACCACGACGATGCTGTCGTCCAGGAGCGGCCCCACGCCGAGCTCGAGGACGCCGCCGTTGCCCGGCGCCGCGTCCCCGTGCTGCGCGGAGCCGGCCGGCGCCTGCCAGAGCGCGGGAGGCCGCGGGGTGTACACCTCGACGCCGGAGGTACCGGGGACGGCGATCACCCTCTCGGTGGGCCCCGCGCCGGGCACGAAATCCACCGTGGAGAGCGCGCGGACGTGGGCGCTGTAAAGCGCGCTCGTCTGGCTCGCGGCGATGGTGATGGTGGCGCTGCCCTGCGGCAGGACCGGCGATCCGACGGCCGACACCGCGAGATCCCGAGCGGCGCGGACCGCGATCGGCAGCTCCGCGGCGAGCACCGCGTGGAGCGGGGCGCGCCCTTCGCCCTCGTCGAACGTCCTCTGGACGTCGACGCGGATCACCGTGTCTTCGGTCACCCGGCTGGCCGTCAGCGTGATGGCGCCGTCCTTGTTCCCGCTCACGCGCCCGGGGGGCGTCATGGGGATCGGGCGCCCCGCGCCGTCGATCAGCCCATACGTCGCGCCCGCCTGGCTGCCCGAGACGCTCACCACCACGCGGCTCCCGTGGTCGACGAGGCGAGGCACCTCGGCGATCTCGGGCGTCGAGACAGGGAGATCCGTGGCCAGCCCGACCTTCACCGTCGCGGTCTGGATCAGGAAGGTCTCGCGCGTCAGGGGATCGAGCTTTCTCGCGAAGATCCGGAAGGTCTTGTCCGCCTTGTCGATGATCGGCCCCTCGAGGATCGCCTTCTCGCCGGTACCGTCCACGGAGCAGGCGGGCACCACCGCCGCGTCTCCGTCGAACAGCTCGTACCTGACGCCCAGCTGGGCGGGATCGATGGTGATCTCGCAAGGGGCGCCGACGTTCACGGTAAGCTGCGCTTCTTGAACGTTCACGTCCCGGATCGGGGTGGTCTCCCCGAGCCCGAGGAGATCGATGAGCCGGTCCCGGGCGCAGCGCACGTCGATAGGTCTCGCGGTGGACATGGTTCTACGAGCTCCGCTCCTCCAGGTGTACGCCCAACGTCGCGGCGAGGACCGCTCGCCGCTTCTGCAACCACTGCTCGTGAGCCGTCCGGAACGCCGCCCAGGCGTCAGCCGCCATCCAGAGCACATACGGTGTCAGGTGCGCCGGCGTCTCCGCGCGGAGGGTGTTCTCGACGAGCTGCTTGAACGCTGGATCGCTGAATCGCCCCACCCCGTCGGGGAGGACGAACGTCAATCGCAGCGAGTAGGGGTCCTTCTCCCGCGCGGCCGAGAGCAGCGCGGGCGGCCTGTCCGTGGGCGCGTCCGTCGGCCCGGGGCGCCCCTGCGCCTCGTCGCCCGGCATCGGTCGGAGCAGGATGTGCTCGACGACGGCGATCTCCTCGCCTCCGTCGAGCCCGAGCGTGACGCGGAGCCGCTCCTCCAGCCCCGACATGTTGGCGGCGCCGGCGGGCGCGAGGCCATCGAACCCCGTCCCCCGCGCGCTGCTGATCCGGGGGTATCGCTGCAGGAGGCGCTGCTTGCGCCGCACGCGCTCCGCCGGAGGGATCGGCGCGGAGGCCGCGTCGTGGCCGGCGATCGGCTCCGCGAAGCGGGCGAGGAGGTGATTCAAGAAGCGGTTCTTCCGCTCCAGGGAGTCGACCTCGTCCGCGGTCTCCACGAGGTCGCCGAGCCGGGTCCGGTGCGCATCGTCGAGCGCGCGGATCTCCTCGAGCCGGAGGCCGGGCTGATCCAGCGCCTGCGTGAAGTACGTCCGCGTGCCGCCGCCGTGGGAGAACAGATCCTTGGCGTGGGCGAGCTGCGCGAACGCGTTGGCGAGGAGCTGATCGAAGAACATCAGGTATGCCGCGAGCTGCCGCGCCTGCGCCTTGCGCGCGGGCGTCGCCGAGTCCGGTAGCCCCGCCTCGCCGACCCCGTAGAGCATCGGGAGGTGCTGCCGTACCGAGGTGTACGCGCCGACGTTCCGGTTGCGCCCCACGGGCACCGCGAGCGCGCTGTCGCCCGCGCCCCAGGGCGCGTCCGGCGCCCGCTCCGGCTTCGCCTGAGCGATCACCCTGCCGGCGCTCATCAGGGTGATGACGGATGCATCGAAGTTCATCCTCGGGACCCGATCCGGGTCGACCCGTAGGGACCACTCCTCCTTGGCGCCGCCCGTGGAGACGCGGATCCGGCTCACCGCCCGCACCGCCGCGATGTCCGTGATCGCGCGCATCAGATCGGAGGTGTGGATCACGGTCCTCCGCGTCGCCCTCGCCAGCACCTCGTCGGAGAGGAACCCGCGATCGAGCCGGGGCCCCTCGAACATCGCCTCGACGCTGGCGCCGGCGCCGAGCCGCTGCGAGAGCGTCGCGAACCGGACGGGCGGCGCGATCTCGTCGGCGATCGCGCGGCCGATCTCGTTCAGCAGCGCCGCGGGGTCGTCCACCGGCGTGATCTCCACGGTGGCCTCGACCTGGATGAGCTGCGGCTCCAGCACCGTGATCTCGGCGAAGTCCTCGCACAGGGGGCGGTTCTTGTGGAGCCTCCGCGCGACCTTGGCCCTGACCTGGGTGCCCCGGCTGTGCTCCGACGCCTCGATGAGGACGCGGTGGAGGCCGCGCAGGTGGACCGGCTCGGAGGCGACGTCCTTGGGCGCGACGCGGAGCTCCTGCTCCACCGGGAGATAGTAGAGCTGGGGCGCGCCCGCCGTGGCCGGCTCGACCCAGGCGTTCTTGACGCCTTCCACGTCGAGGACGAGCCGGCGGAGGTCGGCCAGCGTCACCGGGTGAGAGGTGAGGATCTCCGCCGGCAGGTGGAGGCTCCGGTACGGATCGTCCCCGCCGTCGGCGAGCAGATCCGGGATCTCGTATCCGGCGCGGTAGCCGAGATCCGAGAGGGCATAGCAGAGCTGCTCCAGGAGGGTGATCCCCGGATCGTGAGCGTTGAAGTCCGTCCATTGCCCGCCTGTGATCCGCTCGAGCTGGCGGATCCCCTCCTGGCGCAAGAATTCATAGTCCATCGTACGACTCCCGTCCTCTCTGCGCGTTCACCCCGCGCCCGCCCGGCGGGCGACCTCGTGTCGCCTCACAGCTTCATGATGTAGAAGAGCGCGTGATAAGGAGGTCTGTTCTCGTGTGCCTTCGATCCACCGGTGGCGCGGGTCTTCTCCTCGTTTGCGTTCGGGGTGTCCGACATGGCGAAGGGGATCCGCTCGCCGCTGGACGCGGTATTGCCGCCGAAGTTCTGGTCATCTTTGCCCATGCCTGCCAGCGCGGTGTGGTGGTGGCTCGGCATCTCGTCGATGGTCAGCACGTGGGTCGCCTCGCCGCCCTTGGCGCCGAGGGAATAGGCGTTGCCGGCCCCGACGATGAAGCGGTCCCTCAGATCAGGGGTGCCGTTGGCGCCGTCGCAGATCGCCCAGCCATCCGGGATGGTCGCGGCGGCCCCGGACCACATGACGATCGTCCCGGTCGGGACCAGGGCGCCCTTGAAGATGGCGCTCTTCGCGGCGAGGATCTCTCCCGTCCCCAGCTTCACGGTGTTGTCCTCGGCGTTGACGGTCGCCACCAGGATCCAGTTGCTCGGCGCCTTGAACTTGTTGCCGTACTTCACGATCCGGAACGTCACCGCGACGCTGTCCCCCCCGGGCCGGTGGACCGCGTACAGGGCTTCCCAGTCGTTCAAGACAACACCGTCCGCGTCGCAGGCGCGAACCGCGTCGTCCCAGTCCTGGACGATGGACGGGCTGGCGGACGACGCACTGATGGCCACGTGCCCGTCGCTGAACGTCTCTCCTTGCTCAGCGCACATGGCGATGAACCGCTTGGTCCATTTCAGCTTCTGACCGCGGCCGCCCCAGGTCACGGTGCCGCCCCCGCTCAGCGTGTACTGGGCCTTGGCGTAGTCGTTCGGCACCCCGCTCAGCACGCCGGAGATCGTGGCCCCGCCCGTGACGGTCAGGGCGCCGTTGATGCCGATGTCTCCGGTCGCGCCCTCGATGAAGAGGCGATTTTTGCCGTCACCGTCGCCGATGCAGAAGCCCTTCTTGCCGCCGGCTTGCAGGCTCAGCACCCAGGCGGGCTTGGTGTCCGTCGCGAAGCTCTCATAGAGGTGGATCGCCGGCTTGTCGCCGGCCGTCGACGCCGCGATCTGCACCGGCTGATCGGCCGACTTGACGAGGCCGTCGTCCTTCTGGTTCAGCCCCGCGTCGATGAGATCCCTGAAGTTGCCCTCCGTCGGCAGGGCGTTCTTGACGAAGTACGCCTTCAGCTCAGCACGACTCTTCTTGTTGATTTCCATGATGTGCGATTGCCTTTCTCACCGAGTGGTCGACACGTCGCCTCGGGCGCCCGAGCACGATCCCGGGCTTTCAGTGGCTGAAGAAATCGAGCTCGAGCTTCATGAAGTTGATGCCCGTCATTCGCGTTTCTTCGTACAAACCTTCGCGGAGGATATCGATCTCGTGCTCTCGGGCCGAGGTGAGGACCTCGTCGGGCCTCATCGTCCCAACGAAGGCTCCGCTCCCGTCGACCGGGGGCCCCACCAGTTGGAACCTCTCACCATCGTCGCTGCGAAAGAGCTTGATGCCCGCGACGAAGTCCACATAAGGGCGGCGCTCGACGAAATCGACGATGCTGTTGGCGTAGATCCTCCCGCCGATGGCGAGGTCGGCGCCCTCGGCGTAGGCCCAGGGGGCGAGGAATCGATTGAGATCGTCGTTGAGCCGCTGGGTGTAGTAAGCGTCATCGCCGTCGGCCCGGAAGCGCACGCCGAGGCGGACACGGACGTCCACGTAGTGGGCGTTCACGACCGCGATCGAGGCGGCGCCGGGGGCCCGCGCCGCGAGGTGCTCCCGGATGTCCGCGAGCAGGTTCGTCGGCGCCTTCGGCTTGTAAGGATCAGCCGGCAGCCTGTTCCGGACATCGGGGATGACGACGACCTTCACCGTACCGGGCTCGCCGAGCGTCGCCGGGACGCACTTGACCCGGTAGATCGACGGAAACCGATCGAGGACCAGCCGCTCGTAGTCCCACACCGTGAGCGCGCGCTGCTTGTGGCGGAGGCGCTCGCTGACGCGCGTGGCCCAGGTGGCCGCGCCCTCCGCCGTCCGGCCTCCGTAGGACGCGTAGGGCTGGCGCACGCCCGCGATCTCCGGGATCGCCGAGCTGAGCTTGGTGATGGTCCCGGCGGGGAGCGGCGCGCCAAAGTGATCCGGCGCGTTGTCGTCGTCGACGAAGGTGGCCGTCACCGCCTGGGTGTGGACCGCGACGGTGTCACAGAGGCTCCGGGTGTTTCGCTCCACGGCGGCGCGGATCCAGGTGAGATCGCCGCGCAGGCGGGTGCTGGGCTCCACCGGGTCGAGGGCGAGCTCGACGATCCCGGAGTTGATCAGGCCGCGCGTCGTGTCCGAGATCCGATGGTGCTCCAGCGGGATCCAGCGATCGCCGCTCAGGCAGCTCCAGCGGACGGGCTGCGGCGGCAGATCCGGGTTGGCGCTGCCCTCCGCCATCTCGAAGAGGAGGGAGACGGTCTGGGGCGGGGCGAGGTCGCGCAGGCCGAGGTAGAGCTCGCCGTCATTCTCGTACCTGGGCAGGAAGGGAAGGCCGGCGCTCGATCGCGCTCTCTCCGCGTCACAGGCGCCGAAGGGATGAACGTGGAACACCCGATCCACGCCCGCGGCGCGCGGCGCGCCGTCGAAGCGGAGCTCCAGCGAAGACGCGTAGTCGATCGCCAGGCTCTTCAGCTTCGGCGTGTACGGCGGGCTCACCTGGTACTGCGCGGCGTCGACCGTCGACGGGTTGCCGGCGACGGCGACCGAGAGGGCGAGCGCCTTGCTCGACGCCACCACGGGGTAGCTACCGTGCTGGAAGTCCGGGGCGTTCAGCTCCCATTGCAGGGTGCGCCCCGAGGCTGACAGGTCCTCGTCGATCGAGCCCTCGACGAGCGCCTGGGGGTCGGCCGCGGCGGCCGCGGCGAGGGCCGTGGTGATGGTGATCGATGTCGGATCGGAGCTCCTGGCGCCGAAGAGCGGCGCCGCCTTGGCGAGCTCCGTCTCCCCGCGCCGATCGATCAAGCTGACCCTGGCGGTGAAGGCGAAGGGGGCAGACGGATAGTTGGCGTAATGAGCTGCGAGGTCCGCCGGCGCCCCCATCCACTGGAAGCTCATGGCCAGGCTGTCGAGCTTCTTGCCGGCGATCTCGGGGTGTCCGATGAGGAGGCGCGATCCGACGGCCGGCGCGCTGCCGAACGGCTCGAAGGGCTTCGTGGCGTCCAGCGTCGTCTCGTCGTTCTGAAGCTTGATCGCCCTGAGCCCTCGGGCCTCCACCTTGACGTGCGCGGACACCATCAGCAGGTCGCCGAGCTCCCGGTAGCGGACCACGTATCTCTGGTCTGCCCCCCTCCACATCGGCCGGAGCATCAGCCGCAAGATGGGCCACGGGCTGTCCATCCCGGCGAGCCCCGCAGGCGGCGCCGCGATCGGGTCGGCGCCGGGCGGGAGGGTCAATGTGAATCGAGCTCCGAGGGGGTCGCCTTCGGACGTCGTGCCGGTCAGATCCTTGTACGGACCGATCTGCACCCCGACGGAGGCGCACTCGATCCAGCCCTTGGCGGTGCTGAGCTGGAAGAGCAGCGGGAGCTCTCCGCCCTTGAGGAAGAGGTCCTCGAGGGGGGCGCGCGCCGCGCTGAGCCCCAGGGTGAGGGTGATGACGCGCTGGCCTTCGCCGAGCACCAGCAGCGGAGAGCAGAGGGCCCAACCGAGGACGGGCCGCGGAGCGGGGCCCGCGCTCGACGAGGGCCGCGCCGCCCCGAAGGTGGCCCACGCGGGACCGCCCCCCGCGGTGACCGCCGGGCGGATGGACACCGCGGTGGCGTCCTCCGCCGGGAACAGGTTGAACCATTCCTCCTTCTCCGCCGGCGGCTCGCCGAGCCGATTGCGCTCGGCGATCTCCAGGAGGACATAGATCTCCTTCCAGTCGCTCGCCGCCTCGGACGCCCGGAGCTTTTGGAGATCCGGCTTGCCGAGGTAGGGCTCGAGGCGGTCCATCGCGGCGGGGTCCTCGTCCGGGCTCCGGGCCTCGCCCAGCACGTATCGGATCAGGTCCACGAGCCGCGCCGGCGGCGTGGCCTCGTGGAGCCGCCGGAGCTCGTCTCTGCGGTCCTTGCGGAGCTTCTGCCGGTGGGCCTCTTCGAGGATCGAAAATACCTGGTTCCAGTCGTTCTGCGGCGTGTCGAGGACCTCGCCCATGGCGATGCCGAAGCGCTCCGCCGGCACGTAGAAGTACCCCTCGAGCGCGAGGACCTGTCCCCAGTACGCCTCGATGCCGTCCGTGCCGACAGCCGCCTTCGCGTTGTCGGCGAAGGCCGTGACGTCGGCGGGCGACAGCCGGTAGTCGGGGTCATTCCGCCTCTTCTGCCCGGCGCTCTCGAGGATGCGGTTGATCTCGCCCCACGCGGCGTCGAACCGCCGCTTCAGCTGCATCATCCGCTCGAAGTCGGCGAGCGCGAAGCACAGCGTCCCCTCGATGAACGCCTGCACGTCGCCGCGCGCCCGGTGCTCGTAGAGATCATCGACGGTGCTCACCTGGGCGAGCGTGCCGTAGCTGAAAGGCCCCACGGCCTCCTGGAGGTTCGCCTCCAGGTCCCGCGAGCTCCGGGCGAGCGTGAACGGCGCGCCCCGCTTCTTCGCGCCGGCGAGCTCCAGCGCCGCGTAGATCTCGCCCCACTCGGAGGGCGTCTCCGCGCGCAGCTTCCGCCGGTCCATCAGGTCGCGCAGCGTGGGGGGTGACATGAAGAAGTCGCTGTCCGAGCGCCTCACGAGGTCGCGGAGGTTCGTCAGCTCGGCGAAGTCGACCGGCCGCGCCAAGCCGGGATAGGGCGGGAGCGGGTCTCCGATCGCGAGCGCGAACATCGCCTCGCACGCCCGCTGCTTGTCGTTCGCGTGGCGGCCCGAGATCTCGCGGAGCCCGACGCGCCGTCGATCGATGAAGAGGGAGCTGATCGCTTCGATCCGCGTCCGGTTGACGACGAGATCCCGATCGGTCGCATAGATCCGGGCTCGTCCAAGGCTGTCCGGGCCCGCGTCGAGGCGCGTCCCAGCCGGCAGCAGGACCTCCCGGCCGCGGAAGGCGAGATCGACGATCAGGCTCACCCGATCCGGGACGGGCGGCCTCCGAGCCATCCGCAGGACCTCGCGATAGTAGAAGTCGAGGTGTCGTCCTGTCAGCGTGTTGAGCTCGGCCCGCGATTTCTCGAGGAGCTGCAGGAACGCGAGGAAGAGGACGAAATGCGGCCGGTAGAGCTCGGGCGCGGCCTCGGGCGTGAACTTCCCGGGATCCCGGAGGAACGCCGCGACGTCCTCGGGCCGGAGCTTCGCGCCGACGAACCCGCTCCAGTCGCCCTCCGGCTTACCGCCGGCGCCGTAGTACGTGAGCTCCTTGCCGTAGGCGCGCGCGAACGAAAGGAGCTCCGCGGACGTCCGCTCGTCCACCGAGACGTGGCCGGGATCGAGCGCGGCGAGCGCGCGCCCCGCCTGGCTCGTACCGTCGCGCTCCGCGCCCGCAGGCTCTCTCGACGTGCTCGACATGGATGGCTCTGCCTTTCAGGTTCCCTTGAAGATCTTGTTGGTCGTCTTGAACATGCCCTTGCCTGTGTACGTCGGGGTCGAGTCCAGGATCGGCGGCCCTGGCCCCTTCGGCGGCTGCTTCGCCGGGTTCTGGACCTCGAACGTCGCGGTGAACGTGGTCCCTTTCAGCAGGACCGCCTTGTCGCCGGTCTTCGTCTTCTTCGCCTTCTGATCGTCCCCGAGGGCGGCGATCTTCAGCGTCCCCTTGCCCGGGATGGAGTACCCAGGAATTACGTAAGAGCAGTTGGCGACCGAGACCTTGCCCTCGTCGCCTTCGACGCAGAGCTTCTTCCCGTTCAGCGTCGCTGGGCCGCTCCCCTTCAGCTCTCCAGGCCTGGGCAGGACGAGCGCGGGCGTGAAGCTGGGCAGGAAGATCGCCTTGTCGCCCTCGATGAGAATCAGTCTACTCATGGCGCTCTCACCACCCGGGGAGGGTCGCCTCCGTGAGATAGAACGGGAAGACCATGTTGAAGCGCGAGTTCGTATCCCTGATGGTGTAGTTGACCCCGATGAGCACGCAGCCCGGCTGGGTGTCGCTCGCCGCCACGTCGATCCGATCGACCTGGATCCGGGGCTCGTGCTCGAGGATCGCGTCCGTCAGGAGCCGCTCGATCGTGTTGATCAGGCCCTGATCCAGCTCCTCGAACACCAGGCTCGCGAGGTCGCAGCCGAACGTCTCCGCGAGGACCCGCTCGCCCGGCGAGGTCCCCACCAGGATCTGCAGGCTCTGCTGGATGTCGGCGGGGCCGGAGACCATCTCCACGTCGGCCCCGCCGCGGCTGAACGAGGGCGGGAAGGCCCAGCCTCGACCGAGGAAAGAGCTCTCAGGTCGCATCCGGCTCCTCCTGGGCGGGCTTGCCGCCGAGCTGCTGGCTCGCCTGCTGCTGCACCTTGGCGACCAGCGCGTAGACCCTGGCGAACGGGAGCAGCCCCACCCCCTCCAGGATCAGGTTCACCTCGTCCACCGTCACCGAGAGGTGGAGCTCCCTCACCTCCTGTCCTGATCGGCTCATTGGATGTCGACCCCCTTGCCGCTGATCGTGACCTTGCCCTTCTCGCTCTTGATCTCGATGCCGTCCTTACCCATGGTGATCGAATTCTCGTGCTGGTCGGAGAGGACGATCGATTTTGCGCCGTCGTCGATGAGCAGCTTGTTCTTATTGGCCGTCTCGATGGACACCGACGCCTTGTCCTCGTCGGGGTCGAGGAGCTGTATCTTCGTCCCGAACTTGGTGACGATCCCGCTCTTGTCGTTCTTTTTGCTGGGCTTTCCCATCGCCTCCGGGGGCGCGTTCTTCGACCCGAAGAGGGCCCCCAGGATCACCGGGCGGCGCGGATCGTCGTTGAAGAAGCCCACCACCACCTCGTCCTTGGGCTCCGGCCGGAAGAAGTACCCGCGGGCCTTGCCTGCGCCGGGCGCGGCGAGCCGGGCCCAGACCGCCTTGTCCTGCTTCGCGTCGACCCCGGGGAGGATGACCTTGACCCGGAGCTCCTCGTCGGGATCGTCCTCGAACTCTGCGACGACGCCGACGTGCAGCCCGCTCACCGCGGGCAGGAGCCCGGCCGCCGGCGCCTCGCGGAGCTCCTCCTTGCGGGAGAGCTCCTCGGGCGAGAGCCCGAACTGCACGTCGGTGCGCCAGCCGGACGCGTCGACCCGGTGGCGAAACCCCGTCACCAGCGTCGTGCCGTTGAATCGCTCGCCGACCCCCGCGACCTCCATCACGTCGAGCGGCCTGATGCCGGCGAAGCCAGGCACCGCGATGCGCCCGCGGAGCAGCGCCATCCGGCTCCTCGCCATGCGGGCATCGGCCCAGGCCTGGAGCTCCTCCGCGGCGACGGGGACCGGGTGGGAGAGCGTGCAGGTGCCGTTGCCGACCGCGTCGCCGAGCATGCCTCCGTCGAGGTTCCCCTGGGTGGCGCGGAGGCTCTTCGCCTTGCTGGCCGCGGTGGGCTTCTGCTCCTTCACGTCCCAGGCGACGCTCTCCACGGCGCGGTACTGGTGCTCGGCGTCAACCTCGATCTCGACGTCGAAGATCTCGGTGATGCCATAAGCGAAGCGGTGCCTGGGCGCGCCTTCGACGGCCATCTTCCGGAGCGAGATCTTGCCGTCCTCGACGACCACGAGGAGGCCGAGCGCGCCGGCCCGTGAGAGGATGAAGTCCCACGGCGCGGCGTGGTATTGCACCATCTCCGCGTGCTCCGGCCTGGTCTCGGCGATGGTGCCGACCTCGAGCCCCGCCGCCTCGATCAGCTGTTTCACGATCGCGCCGTCGGTCATCTTCCGGAAGACGGCGCTCCGCCGCGCGCCGGTCAGCTTGACGGCGGCGTCCTTGAGCCCGATCACCAGGACGGAGCCGTCGTGGCCAGCCTCCACCCCGTGCCGAACCACCACCCCCTTGAAGACGCACCGGTCCTCTTCCCCCTCGTATCGGAGCTTGATCTCGATCTTCGCCCCCGGCGCGAAGAAGCCCGTATCACTGACGGCGAACGCCTGCTGCGCGGCGTCGCCGTCGAGCACGCGCAGCTCCGCTCGGGGGATCCGGTCGACCTCTCTCCGGATGTCGATGGAGAGGAGCTCGTAGGCCGGGTCCATCGGCTTGCCGTCGCTGAGGATGGTGGGAGTCACCGCGGGCATGGCGTCTACCCTTCCCCGGAGGTGCCGGCGCCCAGGTTGGCGAGCGGCGGAAAGAAGATCTCCTGGCCGGGGATCAGCCGCCTGAAGTCGTCCAGGCGGTTCCACCGCGCGACGTCCAGGTAGCGGGCGGACGAGCCGTAAATGTCCCTGGTCAGCAGCGGCAGCGTGTCCCCGCTGCGCACGATCCGGCTGTGGGTCAGATCCGGCGACGTCTTGCCCTCCTCCCTGGCGCGCGCCTTGGCGGCCTTGTCGGAGATCAGCGTCACCTCGATCTCTGCCCGGAGCGGGGTGCCGTCGCGCTCGAACGCGGTGTGCTTGATGTCGACCGCGGAGAGGCGACAGGAGAAGATCAGCGATCCCCACTCCACGAGGAGATAATTGGGCTCGTGGATGACCCCGTTGTAACGGAAGGTGACGTCGAGGAACGCCTTCACGCGATCCTTCACGCTCTTCCGCACCGGCGCGACGACCCCCATCGACTCCACGCCGGTGCCGTCGACCACCAGGGTCAGCGTGAGCTCGCTCGGCTTGCTCCGGCTGTACGAGAGCTGCGGCCCGCTGGAGCCCACCCCCTGCTTGGCCCCCCAGGCGATCGCGTAGCGCTGCGAGAACGAGGCCGGGTTGAACATCGCCTCGAACGGCGCCCCGATCGGCTGCCGGCGCCCGACGTCCTTGAACGCCTTGATCTTGAGCTTCTCGAGCTTGAAGAGGTTCAGTCCCACGATCATCTCTCCTTCGACGCCTTGAGGACGCGGAGGACCTCCTTGACCGCCGCCTCGACCACGGCCTCCAGCCCGGCGGCGTCGGGCGCGGCGGCGCGCGCGCGCGGCGCCCCCTCCGGGGGCGCGACGACGGCGCGGATCACCAGCTCTTTGATCTCCACAGGCATGATCACACCTTGATGGTTTGCATGCGGGCGTAGGCGAGCTCGAGCGACTCGATGAGCGGCTTCTTCGGCTCCGCGTCGAGGTCGGCGGTCGACCACTTGACCGGAAAGGCCCTCGTGAAGAACCACGCCGACACCGGGGTGTAGGCCTCGTTGAAGAGGGTCACGATGACGTTCGAGGGGGCGAATTTGAAGAGGGACATGGCGGCGTGGAAGTCGAGGTGCAGCGGCGAAGCCGCGACCACGCCGCGCTCCAGCACCAGGTTGCCGTGCTCGACCCTCGAGGGCAGCGCGTGGGTGTAGAGGTTCTGGCCCCCCTCCTCGAGCGGCGTCGTCCTCACCGTCGCCGAGAGCCCAGTCACCTTCTTGAAGCGGATGTCGAGCGGGTTCGGCGCCACGCCGCCGGCGAAGAAGAAGACGCCGAAGCGGAAGCTCGTGAACAGCTCGCCCAGCGGGACGAGCTCCGGGATGGCAGCGCTCAT

Protein sequences of DBSCAN-SWA_2

>NC_021658|7627900:7712487|7708902_7709319_-|WP_020737288.1|DBSCAN-SWA
MRPESSFLGRGWAFPPSFSRGGADVEMVSGPADIQQSLQILVGTSPGERVLAETFGCDLASLVFEELDQGLINTIERLLTDAILEHEPRIQVDRIDVAASDTQPGCVLIGVNYTIRDTNSRFNMVFPFYLTEATLPGW
>NC_021658|7627900:7712487|7711124_7711847_-|WP_020737291.1|DBSCAN-SWA
MIVGLNLFKLEKLKIKAFKDVGRRQPIGAPFEAMFNPASFSQRYAIAWGAKQGVGSSGPQLSYSRSKPSELTLTLVVDGTGVESMGVVAPVRKSVKDRVKAFLDVTFRYNGVIHEPNYLLVEWGSLIFSCRLSAVDIKHTAFERDGTPLRAEIEVTLISDKAAKARAREEGKTSPDLTHSRIVRSGDTLPLLTRDIYGSSARYLDVARWNRLDDFRRLIPGQEIFFPPLANLGAGTSGEG
>NC_021658|7627900:7712487|7657521_7658817_-|WP_044988781.1|DBSCAN-SWA
MSALRERGALAARDLCAFIDRSPTPYHAVREVASRLAAAGFSELGERDAWAIAPGDRRYVIRGGSTIVAFVAGAEHPAVGGFRVIGAHTDSPNLRVKPSAELSRSGYQQLGVEVYGGVLYSTWLDRDLSVAGRVHIRRDGRVERHLVDLGRPVARVPNLAIHLNRGVNSEGLVLNAQKHLAPVIGLGREADLSALLARAVDAPRDAVLGFDLCLYDTLRASIGGLADEFIFASRLDNLASCHAATAALIGAGAPGAATRVIALYDHEECGSRSAVGAAGSVLRDVLARIVDTFPAREPQAFARAMAGSLLVSADMAHAVHPNYADQHEPRHAPQVNRGLVIKSNANQSYATDGATAAELEAHCHDAGYAPQRFVVRSDLPCGSTIGPITAAALGMATVDVGAPMLSMHSCREMAGTLDVHLAIETYRRALT
>NC_021658|7627900:7712487|7650671_7651844_-|WP_020737256.1|DBSCAN-SWA
MASDEEGRADRAGATGAAGIDGAAGVAGATPGFLPASRELPLFAELPELAGQIPWRPLAHAPTPVVPCAAIEGYLGRGGVWVKRDDRISPLYGGNKVRRFEFLLADAERRGARTLVTVGGLASTQVTATALFGRALGFAVTAVLFDQPITRFGRDALLAGAASGAELVHGGGYATTAVRAIRALRRADRPYFILPGASAALPCLGYVDAMLELAEQVRRGEAPRPDRIVVPSGTGGTLAGLALGAAMLGWPTTIVGVRITERVASNRAVVRYEVGSMERLLARRAPRFTRRRLPPVRFAIDHRAIGPGYGAPTPASIAAIPEVERLIGVPGEITYSAKALVALREIGRDHPGETILLWQTLSSARPPLAEGGAAALPPAFARFFEGDVAC
>NC_021658|7627900:7712487|7700888_7702880_-|WP_020737284.1|DBSCAN-SWA
MDYEFLRQEGIRQLERITGGQWTDFNAHDPGITLLEQLCYALSDLGYRAGYEIPDLLADGGDDPYRSLHLPAEILTSHPVTLADLRRLVLDVEGVKNAWVEPATAGAPQLYYLPVEQELRVAPKDVASEPVHLRGLHRVLIEASEHSRGTQVRAKVARRLHKNRPLCEDFAEITVLEPQLIQVEATVEITPVDDPAALLNEIGRAIADEIAPPVRFATLSQRLGAGASVEAMFEGPRLDRGFLSDEVLARATRRTVIHTSDLMRAITDIAAVRAVSRIRVSTGGAKEEWSLRVDPDRVPRMNFDASVITLMSAGRVIAQAKPERAPDAPWGAGDSALAVPVGRNRNVGAYTSVRQHLPMLYGVGEAGLPDSATPARKAQARQLAAYLMFFDQLLANAFAQLAHAKDLFSHGGGTRTYFTQALDQPGLRLEEIRALDDAHRTRLGDLVETADEVDSLERKNRFLNHLLARFAEPIAGHDAASAPIPPAERVRRKQRLLQRYPRISSARGTGFDGLAPAGAANMSGLEERLRVTLGLDGGEEIAVVEHILLRPMPGDEAQGRPGPTDAPTDRPPALLSAAREKDPYSLRLTFVLPDGVGRFSDPAFKQLVENTLRAETPAHLTPYVLWMAADAWAAFRTAHEQWLQKRRAVLAATLGVHLEERSS
>NC_021658|7627900:7712487|7629635_7631285_-|WP_020737246.1|DBSCAN-SWA
MSTSFIARSLSAAALALCAASGLGCAPPKPPLTCASQGGAPWVELSSQHVVLRTDLDRSEARGVLAELERSYNALEDVCFPSDAPEPFRMQIVLFAREQDFRRFSPAPSSGVFFHALPNDIERAPTMVMYGSLGEPARITFQRGLAYHFIAQSIGPAPPWLKQGLAQFYSTFRVRGGYAYVGSALPYHDFLKGASGRTVRNGAFTLQLVPASEAASAAELIRARREDFYSLADDPSEAERRRVALNDLSSWGLVHMLLNGPDPYVQRFASFLEAASRGAPVRQAFQDAFGDISPEQLERDYRSYLVGTRPIRKIGPYTAPPPPPPLVERAMSDAEVHVLWARLRRWQGDGRAWAAAQLDEAVAHEPNNPDVRFWRGLFRTAESRLREAEQELTAALAAKPTDPRYLLAMAKLIRAMSSRRIITPLQAIVRTAPLIDRLSRTAATAEQLTFVARYRIQLRDLDEAQAFVQRALKTDPSCVRCYDTYGMLLLLQGRVTEAITAASRARDLLPEGVENPLIEARLRCFQAHEKAVRDGAPTRPEKCFDPLRE
>NC_021658|7627900:7712487|7667782_7668763_-|WP_187345639.1|DBSCAN-SWA
MSGRQAKRVLIVEDDETNAEAAVEWLREQHYQVERASALEDGLAVAERFQPDVVMLDLQIPSRPGRADEHTDNGFRMLDALLRAEPFRPVVVATAHSRNRELMRQAMQRNRGGHFLFKDDQDLRAAVLRAVAVALESPAYVAHSTVRAFEELIARNPREEEIRIFLRKSWRVLLGPRYRECHSPYEVDRGVKVDLLFVRHDGFPDIWELKRPDQQVFKEYGDRLHHSEECARAVGQVMEYIDLAEKQTGGQVSYEVRKNVRVSLHRPRGFVVIGRTGSQRERDRLALDNSFMAGITLMTYDDLIEDAREVLVFLRDYRNGGEAPSV
>NC_021658|7627900:7712487|7688763_7690455_-|WP_020737277.1|DBSCAN-SWA
MSDIELLLCHADDHRPVLEEGLPLESAADEPQPGGEELIHDFADFSDDPNDLSLQRWSVIAPEGPAGDALLALVEPLIRKREQDQGAPVVPYRVPAGMDADAAIRWSKSVYHDESVALEDLPRYLLVLGDLDEVSLELQQAMASEALVGRLVSRSAAGYAAYVDKLLSSERAPPREARARALFFTAQDGTAATTIGHRALVAPSVARCRDTRQRGGFKARDIEEIGFDGAEAARSALLEQLGRPEPSMLFTMSHGLGAPRRGWTSADEQRAVQGAMSLGSGVRIAAEDLGDRPFLPGGIWFFLACYGGGTPAASAYHHWLARLRDAGGFGGRVDGVLAGLPRPGDRPFIAALPQAALASPRGPLAVMAHIDLAWTYSFQDMGPDGKDRASRFEGVFSSLVKGARVGNSYNELLRYLGNANHELAAMYNQEARAETAGKPLAPDQGRAKRRANLWMLREDLAGYVLLGDPAARLAIDRDIRAVKATPAPAEVRSPVPQLPAAPPAPAAGRARDAARMQRAVHEKILGEEGDRKIAERYGITREELQRWYDAYCEAGLAALGELP
>NC_021658|7627900:7712487|7668759_7670895_-|WP_020737269.1|DBSCAN-SWA
MEDERRTPPSLEARVTEVLEACDYEVQQAVGLEQGVIDWFATPRSSFIRPRTYFRVLPRSPEDLNETLAELESARVARKADRAVAIVMSERLPGGYAPDLVGRTSNVLTFRRWLLEISGIAEDARQRAQPSEQERRGQTYLPRRGRLADGAVVPLEPFIEAWMDRPDRPMLVIEGPPGSGKQAALKHAIDRAAVRFSHDPEQATLLVDIANMYLASVMQIALDTGAVVPVITRSSLLRAAPMQEQAWRCLLTARMADTLGPPPPGIGVVRIVLVPPSSEEITSWYRACLGSQELTGRLLRARAENDSFRSLSGALPNLGRIVSAVKSIELADRPASIDAWIASVVVAYVDAMKLEERALPPSGMEGEDALSRYLEDIALAQFAMGLRRAAEFSVPRRFERTRGALDSLLTWFDFGKVEHKNHLLRDYYIARKIAREVSAGNSEILLRYQLPPFVFLFLALIAPEVSAQVTQGRVAQLDEKVRSEVERKLQLTFAHLLNRPVGMVRARLREIRDGIDRERATALARSFEQIEEELRFIQSLAERTRLWETAPDEPIEEVAVRPVIEELGRELNARHPAVTLVIDVESSVRVRAMRDALREVMQCLMENAFHATVMGTEDRASCVTAVTRPIGAVIRIEIRDTGCGVPPEDRQRIFEPLVTTKKGGAGKPRGTGLGLPIARRYAEHMHGHVGLDETASETCFYVDLVAWTEGA
>NC_021658|7627900:7712487|7702945_7704160_-|WP_020737285.1|DBSCAN-SWA
MEINKKSRAELKAYFVKNALPTEGNFRDLIDAGLNQKDDGLVKSADQPVQIAASTAGDKPAIHLYESFATDTKPAWVLSLQAGGKKGFCIGDGDGKNRLFIEGATGDIGINGALTVTGGATISGVLSGVPNDYAKAQYTLSGGGTVTWGGRGQKLKWTKRFIAMCAEQGETFSDGHVAISASSASPSIVQDWDDAVRACDADGVVLNDWEALYAVHRPGGDSVAVTFRIVKYGNKFKAPSNWILVATVNAEDNTVKLGTGEILAAKSAIFKGALVPTGTIVMWSGAAATIPDGWAICDGANGTPDLRDRFIVGAGNAYSLGAKGGEATHVLTIDEMPSHHHTALAGMGKDDQNFGGNTASSGERIPFAMSDTPNANEEKTRATGGSKAHENRPPYHALFYIMKL
>NC_021658|7627900:7712487|7647751_7648570_+|WP_044988780.1|protease|DBSCAN-SWA
MRYTPAGWVLLVRDEDYDFAATSIDRYEAENRDWPPRRARERPRHPPSIAAGVAFAALALFFFLVTGPASGGGRLFQRGASVADLVVGPEPWRAITALTLHADSAHVIGNVISGTVFASAVQRRLGPGGAALAVVASGAIGNFANALWHHGLGHHHASIGASTAVFGAIGLLATTQLMLDRAHDKDSGEKRHLLQLVAPLVGGLSLLGALGASPRADLGAHAFGLLSGAAIGLVAGLSLRNRPAPRRPLVQVALGATATGLVLGAWQLALRA
>NC_021658|7627900:7712487|7696350_7697706_-|WP_080682310.1|DBSCAN-SWA
MQIAVHRSTPKTSRSAARASRARRPAPLLAQSRTMTPARPPAAPGRAALERAFGAELFAGAAAGPSVGGGSGPDRAVNLTGIPSPVKAKMEAAFGTDFSGVRVHPSSSRAAALGALAYTQGSEIHVAPGQWAPETTRGQELLGHELAHVVQQRAGRVQATAQYKGIKLNDAPALEAEADAMGARAAHTSAGLPRAMARAPETPSEPLRGSSAVVQRMKRDQIDPGDVATVRPSMDNYKSHVALRVTHFFTVFLKAVLLWRKCASQGALPNLFTNNAAAQAGIGFRIKNAATASPGEGKYDAAHLTNVTLVKSLFSGLPLTPRDQENLDDLYRATAATTPQFQIANVTSDKIIDRQMTSFKNDMIRDLNAGAALDHNFIQANLAKFLTDLEIDLQVKSQQYPTVGAAAADQLKADSYAAALKIVTELKTQNFDECFYAIVNEVEAYRRYNLT
>NC_021658|7627900:7712487|7693069_7694785_-|WP_049949635.1|DBSCAN-SWA
MSRNVFLFELAVTRGDAEEVERALLSRASAFALGAFPTLDPALFAHRILRGKGASYTWEIGLDEIEEARRAELHAALLEQIQTSLAGVAELRSSAAYADLTLPAPGPEPARARGGPGGALSFADGDLPVWEDHARGSGAAEAGSALPEELTAEIAQRRAAVPVEPGLKPWGAGHVYTGSADKAHLAYLHGYIDARAARASAADRRKIMAFRALQAREGSTAAINTYDDQIVTWGTGWGGRGWLGKVMERATANDAVREALGAAGVRYRGSNVYDVVDLDAGTVVTGGEEALEILRRSVPLLHLLIDLARNPATRDAVTEAQLRTFMDGSGNICGADAIATQALFNLIAHLKHWAPGYVIGCLEWAVPQLGPGSPSEERDRRLAALVGRYFYGKARKHRWIPDFRQFRLYFRHMKDDGLDCLDEPFLQAAGPPGDDPFAAAMGAPAAAPPPEAPSPPKDPRLTRAALAGQPDLESVASGRGALRRGARGSGVKALQEALIALGESVPGGADGAFGPGLEAAVKQFQAERGLAADGVIGAATLAALDAALAASAATRAAAAETSNRREEEEHR
>NC_021658|7627900:7712487|7666447_7667722_+|WP_044986200.1|DBSCAN-SWA
MERRDFLKLASMAGLGVVAAGALSRDAAAAGPYEGPLWINIHASGGWDPTSLCDPKGAMSVEEQKTRDAMNRSYLREEIGTAGNIKFAPVGGNAEFFKKHYSRLLIVNGIDTSTNSHDAGVRNTWSGTLREGKPGFAALVAGVHGGALPMGFISNGGYDTTANVVAVTRVPDTGLLQRLAYPNRTDPSNSENREQYHTDATMTRILEARQARHMAKLDQQRLPHVKQAMSTLFTSRVGQNELKQLIQFLPAEFERASLRRQAQVALAAYQAGICVSANLSIGGFDTHGNHDDNHIPRLTDICDGVDFLLTAAEEQGIADRIVIVVGSDFGRTPGYNEGNGKDHWNITSMMMVGAGIPGNRVIGATDDRHNPLEVDPVTLEPREGGVRIKPGHIHKALRKLAKVADDPLAQRFPLSEEEDLPIFG
>NC_021658|7627900:7712487|7653061_7654147_+|WP_020737258.1|DBSCAN-SWA
MARVHNFNAGPAGLPLPALERAQRELIDFEGTGMSIMEHSHRGKAFDAVHNEAIALLRQLLGLSDDYHVLFMQGGAAMQFAVVPMNLLPPGRSADYILTGGWSEKALEEAKRVGAVRVAASTAVDKRYTRIPHQSELSLDPNAAYVHMTTNNTLFGTQWHWLPETGNVPLVADMSSDILWRKMDMSRFALIYAGAQKNIGPSGITVVIARKDIVDSGRKDIPVIFRYATYAANNSLYNTPPTFAIYLMRNVLAYTLEIGGLEEVERRNRKKGELLYETLDAHPDVFRAPVEKESRSFMNVVFRLASEEMEKRFVAEAAKEGMVGLAGHRSTGGIRVSIYNAVSVESVERLTAFMRDFAKRA
>NC_021658|7627900:7712487|7679749_7681966_+|WP_049949634.1|DBSCAN-SWA
MLLFATFAIAFGAPAPALADEVPAQVLVFQSDDPTAPAMSSITGELRESVRVGWGGPVTFKLEFLDLSWFDTPDYARELRRFYRAKYSGYHPGVIVALRLDVLRVVLDLRRELWSGVPVLFLSEDRSAALAAPAAPDVTGIWLDYAWLRTAEGALRLLPDTREVALVMGASPWERARHDGIARDLGPLTGRVALLDLASLPLAELDRRLAALPENAIVLFDTFYMDGAGNRFVGLQAFERIRAQTQRPFFSVHGVGLGKGIVGGEIVDYGRVGRDLGGITLRLLGGASAASIPIRAADANALAFDARELALFRIPEERLPPGAEVHFRVPSFWDLYRRWAVGAAVAVTLQTTLIAALVIERRRRGRAQAMSDAVLASMVGFVAVVDRTGVMLRTNRTWARAPREGAPGPLDRVAEGESYLGAFQRAAAAGDADAGRVVELVEGVLAGRDVEGTAEYRHDGAERWTEVRARRLSWKDGGAVVSHFDVTGRKRAERQARESLSALSHLNRVAAMGELASSIAHEINQPLSAVLTSAQAAEILLRRAAPDVAEVGAALEEIVAGARRAGQVIRRMRVLLKKGEAQRERCDLNEAAREVARLVGNDALLRGATIALELAPDLPAVRGDAVQLQQVVLNLISNALDAVSGRPYGDRRVIVRTARADGRVALAVEDSGEGGAMDDLERFFEPFFTTKSEGLGLGLCISRSIADAHGGRLWAERAPAGGVAARLELPGEAAQEER
>NC_021658|7627900:7712487|7644278_7646615_+|WP_020737251.1|protease|DBSCAN-SWA
MTMRISPEVEIAFSLATREASRRRHEFVTIEHLLYALLFDEETAEVLRHAGGDTPLLKKKLERFLDEEIEALPDDADTSPTLSLGFQRVVGRAAMHVQSSGKKELKGANVLVAMFAERDCPAVTLLGEQGISRFDVVNYISHGISKTGQDDSLREESSSDEGGEPGGAQPVKDPLAAFTMNLNKEAAEGRIDPLVGRENEVARTIQVLARRRKNNPLLIGDAGVGKTAIVEGLAQRIEKNDVPAPLKDATVYALDMGALLAGTKYRGDFENRLKAVLRALEKQPGSVLFIDEIHTIIGAGAASGGTMDASNLLKPALASGRLRCIGATTFQEYRGHLERDSALARRFQRIEVTEPSVDDTTQILKGLQKRYEEFHKITYTPEALDAAAKLSARYLQDRRLPDKAIDLLDEAGAAARLKHGDGYTVDTADIELVIAKMAQIPPRQVSTSDKAQLKDLEQSLRSVIFGQDEAVKQLSSAIKLSRAGLRAPEKPIGSFLFSGPTGVGKTELAKQLAKALGIGFLRFDMSEYQERHTVSRLIGAPPGYVGFDRGGLLTEAAAKTPHAVLLLDEIEKAHPDVFQVLLQVMDHGTLTDNNGKKSDFRHMVLIMTSNVGARELAQARVGFGERGSAGDDDKAYKNTFSPEFRNRLDARIMFRSLDPSVMGSIVDKFIGELAAMLADRSVTIDVTERARAELSTRGYDPANGARPLGRVIENEIKRRLGDELLFGALENGGNVTVDFEGGDFTFKFAAANGSGSGSGGDAEKAKANGAKVEPAAVG
>NC_021658|7627900:7712487|7660272_7661433_+|WP_020737264.1|DBSCAN-SWA
MELEAHVHDTIREIPESEWNALHGASEAPFLSWAWFDALERTGCVGEEAGWLPHHITLRVEGVLLAAAPAYLKDNSEGEFVFDHGWASASHQLGAPYYPKLVVAVPFTPATSPRLLVRRPEDRPALLAVFAETLRELVARSRISGAHVLFPTEDEAAALSGAAMAHRCGIQFQFENEGYGSLDDFLARFNAKRRHQIRREMREVTQQGLSIETLRGADITPEIVDVMFGYYVSTVEKFAWGRQYLNRAFFEEITARLRSSGERAGGEGGVEVVLARDGKRPIAGAFNLAGPTTLYGRYWGASEERPFLHFNVCYYHPVEDCIARGLRRFEPGAGGSHKLVRGFAPRITHSAHHLAHPRLDAAVRDFLVRERAVVRAKTADASVAFR
>NC_021658|7627900:7712487|7697783_7699295_-|WP_020737282.1|DBSCAN-SWA
MSAPRHQIRRQILEVTVQDREAAWRLQTELGRIHTQRLEAVIDRCCTELGAPDRLQRVARVEVDLGQIDPDHLERDLVDKLGPLLREGLAARLREEDEETALRGGDPEVISRLELVASFARTGNLPWWADSTRPRLLDETLGLLLERAARPLVALIRALAREGGALARIVRHSRDAQLWALFDALVASSRADLPSVPVELVALLRAHRAVAGATPDGFRACVWTGALRTACLEESPSDGRVGFFRDALARIALEAGVSLGSLLAGLHAPLGPNPSAWPGALAEVVQSPGAAVSSAVGQRPGAVAERSVREARGGDPSSDPGATAADEALSVDPAHGDADEVYVDNAGLVVLWPFLGHLFERLGLFADTQFKDRRALHRAAGLLQHLCTGELEPAEYQLPLARVLSGMRMTEVFDFGPPVTEAEAEECVRMLTAAIASAPILGEMSIAGFRGSFLVRKGALSARDGAWHLRVERASYDVVLDRFPWGMSWVKQPWMEAPLSVEW
>NC_021658|7627900:7712487|7671098_7673612_-|WP_020737270.1|DBSCAN-SWA
MGALSPPGSGGARRWLAAARPRLPLLLRRAARIALALAVAPWLLLAVAAALTKLPPELAAPEERAVSTVLLDRHGTVLRELRAGDGARARWPPLAEAGDRIQRALLAAEDRRFAVHPGVDPIAIARALGQLAAERRVVSGASTITQQLARALVPRPRTVRGKLREMALALRIEASLSKREILEQYLNRVAFGPGLRGVEAASRFYFDKPTADLSLAEAAALASMPRGPALYDPRRGAGPLERRRNRVLDRMLAAGLAGEAEVARARAEPIALAPKGSGLGAPHLVRAVLGGALGPEAGGSGAAPLRGRASSITLTIDRGLQREIEVLAQQTVRGLSDRDVGAAAVVVLENATGEILAYVGSHDIEDAAGLGHNDGVLALRQPGSALKPFVYELAMEQLGFTAATVLPDVELSFPTADGSYAPRNYDGRFHGPVRLRDALASSYNVPAVWTAAALGPERVLARLRELGLASLDREPSRYGVAIALGDGEVRLLDLANAYATLARGGVYLPVRAVRALSLASPAGGPEDAAIDPPGRGARVLDAARARVIVDILADDKARIASFGEGSALDLPFPVAAKTGTSKGFRDNLAVGFTPDVTVAVWVGNFDGSPMGGVSGITGAGPLFRDAMLAAARVRPPRPFDPPDPDHLAEVEVCGLSGMKPTAVCPHRRRELLPRADAAALAPCDMHEAVRVDRRNGLRAGACPDAAVEERVFERYDAELTAWARAAGRPVAPEEASPLCGPLPGGDGVPPAGARVRVAYPPDGARFVLDPSVNSQQAIRLRADVPPGVRRARFVLDGRPIEVGPPFSLDWPLVAGAHRLRVEADGASAGEEIAFSVE
>NC_021658|7627900:7712487|7683020_7684694_-|WP_020737274.1|DBSCAN-SWA
MILREDRLDLLLADADERRPVLDEGLPDDTAQRAPRPRKARDANHWRRTDADRNDLTLQRWAVIAPEGREGDRMLEAVQPLVALREAEQGSPARVVRVPHGMDAKRSADFRRDIYWSEEVAEEDRPLYLMMLGDLHHTSVELQHALANDALVGRVHFADGAGETDLAGYAAYAEKVVRYARRGTPETSPELLFYAAPDGSAATVAGKLRLVDPSLATSMEAHARGKLPAASVREISAGSVDDLLAGGGGARPSVLLSVSHGLGAPRRGWRREEDAWRRQGALVIAHDEILDAERLRGQAFLPGGMWFYLACLGAGTPAESVYHAWLSQLAQEDRYGGSLRAVLHSLPASGNRPFVAALPQAALANPAGPLAVIGHVDLAWTYGFSGTKSLSESKKSRIYRPLEVLVRGSRAGIALEALMEFYRGANDDLAQSYQREADARAAGRADPTDRADRAHLWMLRNDLRGYVLLGDPAARLPLQQLALRAEAPAPAEVGCTPPEAPAGGAAPGAQAREAAVLAMIRGDEAPRAIAARARVPLETLWSWVDAYRAGGRERLGR
>NC_021658|7627900:7712487|7659143_7660283_+|WP_020737263.1|DBSCAN-SWA
MYRLVRPLLFALPPRLAHELGMLALAPLEHAAPLRALVRARLAPRDGRIAVRAMGLDFPSPLGVAGGFDKDARRARALAALGFGFVELGTVTAQPQAENPPPNLFRLPADRALINRLGFPNQGAARVTERLLDRGGAAAVGVPVGMSIGKSRVAPLDPIEPAIEDYLASFREVRRAADFVVINVSSPNTKDLRAMQGPAIARALLSAIMRENRGAGRPLPLLVKVAPDLGDEELEALLAVVEEVGLAGVIATNTTVRRDGLATSPSAVEAMGAGGLSGPPLRQRSLAMVRRIRARLGGGVTVIGAGGVESAEHAMDQIEAGADLVQLYTGFVYGGPLLPAAIARGLSELVARAGARSIHDLVGGRTGSAARAAMIGHGA
>NC_021658|7627900:7712487|7712010_7712487_-|WP_044988787.1|tail|DBSCAN-SWA
MSAAIPELVPLGELFTSFRFGVFFFAGGVAPNPLDIRFKKVTGLSATVRTTPLEEGGQNLYTHALPSRVEHGNLVLERGVVAASPLHLDFHAAMSLFKFAPSNVIVTLFNEAYTPVSAWFFTRAFPVKWSTADLDAEPKKPLIESLELAYARMQTIKV
>NC_021658|7627900:7712487|7640304_7640904_-|WP_044986197.1|DBSCAN-SWA
MRGGAGGGGALARGGALARGWVLARGWVLARGWVLALAGVMGALGAGAGCEERAGVSPAAKKGFGEACADGAECASSVCAAIGGVCSKGCRVDRECGAGYVCRSRDDGPDGVCSKPQGRAPGEACMTAVECQHGRCLHRAGALDQPGHCSAYCESAGDCPAGLKTCEEIADSAGRKMCLPGEGGAGTAAPGAKGKASER
>NC_021658|7627900:7712487|7694883_7696170_-|WP_044986203.1|DBSCAN-SWA
MQIVVDRSAPKASGNAARTSRARPPAPMHLPRRAPPPTRPPAEPVRASLERAFGADLFAARAGAAPAPRSTAPPAGAQRVDTAASEALAQKPAEGAERLLEAASALAAALPASAGKAAPPKLDWETHPAHLRLSERVAALEERYPGLELRWVIDWARRFIEQVVAKADATPADKGVFDDRLEQMAKELAARIDATNPQLRAGSGAPQKGISGGAGTHLWTGGVDYKAAQAAARRAAEAESQAGNLDAASVEMTIAGELLDSINFSGNGIDYAPEADKLWNELSRAFAGNARGTVRVHTLYGVRSPSIFYSVESLALLLVLKAQEVREKVGKKQDGPVVDEIRMVIYFRKGEIDPETGQLSIPKDESGRMKEELVKQREDRVTTSYQLERARANAWDKSLAWEPTFAVAGSVKHRAALLDARRAAASPG
>NC_021658|7627900:7712487|7704230_7708445_-|WP_020737286.1|plate|DBSCAN-SWA
MSSTSREPAGAERDGTSQAGRALAALDPGHVSVDERTSAELLSFARAYGKELTYYGAGGKPEGDWSGFVGAKLRPEDVAAFLRDPGKFTPEAAPELYRPHFVLFLAFLQLLEKSRAELNTLTGRHLDFYYREVLRMARRPPVPDRVSLIVDLAFRGREVLLPAGTRLDAGPDSLGRARIYATDRDLVVNRTRIEAISSLFIDRRRVGLREISGRHANDKQRACEAMFALAIGDPLPPYPGLARPVDFAELTNLRDLVRRSDSDFFMSPPTLRDLMDRRKLRAETPSEWGEIYAALELAGAKKRGAPFTLARSSRDLEANLQEAVGPFSYGTLAQVSTVDDLYEHRARGDVQAFIEGTLCFALADFERMMQLKRRFDAAWGEINRILESAGQKRRNDPDYRLSPADVTAFADNAKAAVGTDGIEAYWGQVLALEGYFYVPAERFGIAMGEVLDTPQNDWNQVFSILEEAHRQKLRKDRRDELRRLHEATPPARLVDLIRYVLGEARSPDEDPAAMDRLEPYLGKPDLQKLRASEAASDWKEIYVLLEIAERNRLGEPPAEKEEWFNLFPAEDATAVSIRPAVTAGGGPAWATFGAARPSSSAGPAPRPVLGWALCSPLLVLGEGQRVITLTLGLSAARAPLEDLFLKGGELPLLFQLSTAKGWIECASVGVQIGPYKDLTGTTSEGDPLGARFTLTLPPGADPIAAPPAGLAGMDSPWPILRLMLRPMWRGADQRYVVRYRELGDLLMVSAHVKVEARGLRAIKLQNDETTLDATKPFEPFGSAPAVGSRLLIGHPEIAGKKLDSLAMSFQWMGAPADLAAHYANYPSAPFAFTARVSLIDRRGETELAKAAPLFGARSSDPTSITITTALAAAAAADPQALVEGSIDEDLSASGRTLQWELNAPDFQHGSYPVVASSKALALSVAVAGNPSTVDAAQYQVSPPYTPKLKSLAIDYASSLELRFDGAPRAAGVDRVFHVHPFGACDAERARSSAGLPFLPRYENDGELYLGLRDLAPPQTVSLLFEMAEGSANPDLPPQPVRWSCLSGDRWIPLEHHRISDTTRGLINSGIVELALDPVEPSTRLRGDLTWIRAAVERNTRSLCDTVAVHTQAVTATFVDDDNAPDHFGAPLPAGTITKLSSAIPEIAGVRQPYASYGGRTAEGAATWATRVSERLRHKQRALTVWDYERLVLDRFPSIYRVKCVPATLGEPGTVKVVVIPDVRNRLPADPYKPKAPTNLLADIREHLAARAPGAASIAVVNAHYVDVRVRLGVRFRADGDDAYYTQRLNDDLNRFLAPWAYAEGADLAIGGRIYANSIVDFVERRPYVDFVAGIKLFRSDDGERFQLVGPPVDGSGAFVGTMRPDEVLTSAREHEIDILREGLYEETRMTGINFMKLELDFFSH
>NC_021658|7627900:7712487|7655086_7656031_-|WP_020737260.1|DBSCAN-SWA
MLRYRADIKTLLFVATYFALVAVQWVYAPRALWLAIPLLAMTCVFSFLGAVATHNSVHCPVFRRRWMNRAFQVALTLTYGHPVSAYVPGHNLSHHKYTQSRRDVMRTTKVRYRWNLLNGLLFMSRVVRDILPADMRYFKAMYRRNPPWFRQMLLESAVFLGAMGALLALDWKKFIIYVLIPHQYAAWGIVTMNYLQHDGCDEDSEYDHSRNFVGRLVNWWTYNNGYHSIHHMEPGLHWSLLPAEHARRVAPFIHPNLDQPSLLAYLFRTFVWPGKRLRYDGAPVVLPQEEPDEEWIPGPKETPSDVSLGAIAPS
>NC_021658|7627900:7712487|7646916_7647300_-|WP_044988779.1|DBSCAN-SWA
MSTAITQGIRVTVSTVYVPTQSSPTEHRYVFAYTVRIANEGAEPAQLRTRHWIITHGSGKVEEVRGPGVVGQQPSLKPGEHFEYTSGCVLETPRGSMRGTYQMHRPDGRVFDAEIAPFTLAMPHSLN
>NC_021658|7627900:7712487|7708460_7708895_-|WP_020737287.1|DBSCAN-SWA
MSRLILIEGDKAIFLPSFTPALVLPRPGELKGSGPATLNGKKLCVEGDEGKVSVANCSYVIPGYSIPGKGTLKIAALGDDQKAKKTKTGDKAVLLKGTTFTATFEVQNPAKQPPKGPGPPILDSTPTYTGKGMFKTTNKIFKGT
>NC_021658|7627900:7712487|7643883_7644282_+|WP_148313905.1|protease|DBSCAN-SWA
MLPKRELPPSAARRGGALAILPDGFMPNDPEEREDRQGDLATERERKVEKARRYKVVFHNDDYTTMEFVVLVLMKFFHRTETEATHIMLSVHHRGHGVAGVYTKDVAETKVAQVQDFAKEHGMPLRLTAEPE
>NC_021658|7627900:7712487|7681962_7682592_+|WP_020737272.1|DBSCAN-SWA
MTGVTARVVVIDDDGAVLRSVGRLLGASGYEVELFEGARAFLASAAAAPDARAGCVIVDLAMPELGGLDLQAALRASGCRLPLIFITGHGDVRASVQAMKEGAVDFLLKPLEADEVLAAVRRAMDLDARARAAREEQAALAARLDALTPRERQVCARIARGQLNKQIAAELGLAESTVKQHRASATAKLGVASAAELAALLERSRGPGG
>NC_021658|7627900:7712487|7639136_7640003_+|WP_020737248.1|DBSCAN-SWA
MTKTRSTSKNSKPSVSARQIFTTSDANEAYRHFLPRVQAEVPAERAEVCRLSIELVRANVDRGVQAVLPHLGRVREKLPLCPIDDVLELPSLALGLVAAAGRVATAASEREIEARLEKFRPMRDLTLRQLEIFADLKLVPKQRVAAIRRGSGPVDSARDGVDIAGMFDELADALDGKHPFSRDYLAEMAEHASWLLVQLKPRGAQQKPSERSPEAIVRDQFWTVIHQRYEHLREAGVAVFGLRQLDAHVPPIGARTPAPSTAQTSGTAKPGSAGPVPPAAAPDPTAEP
>NC_021658|7627900:7712487|7641106_7643677_+|WP_020737249.1|DBSCAN-SWA
MSNPIDVDPNRQRETPAQREPSQRDTPAAFFRGNTAPDARTGMHPVALRRAFADHLHYSRARESLSATPFDRYVALALSVRDRLVDRWTKTQHTYYEQDVKRGYYLSAEFLLGRALVNNLQALDIYDSYKTVLAELGLNLDDLVEQEPDAGLGNGGLGRLAACFLDSMATIGLPTYGYGIRYEFGIFEQAIRDGYQVERADEWLRFGNPWEVERPEHAVPVSFGGYTERVPDKRGGFRVIWRPAEQVVGVPFDTPIAGFQSNTVNTLRLWSARAGEEFDFELFNAGDYVHAVHEKNQSEVISKVLYPNDNFDKGKELRLRQEYFFVACSIADIVNRYNRVHPDFSRFAEKNAIQLNDTHPAIAIAELMRVLIDEHLVTWEDAWKQTVASFGYTNHTLLPEALERWPVALFERLLPRHLEIIYEINRRFLREVMDAHPQDHDRVARMSLIEEGHERHVRMAYLAVVGSHSVNGVAKLHSELVKRDLLRDFYDLWPERFNNKTNGVTFRRWLLACNPALAALVTEKVGPRWVTEFERLRELERHLDDPEFIERIASVKRANKAALAKFIGQELDISVDPASIFDVQIKRLHEYKRQLLNALHIVALYLRQKRGEHVTPRTFIFGAKAAPGYRQAKLIIKFIHAVAYVVNGDRRQSALRVVFMPNYRVSLAERIIPAADVSEQISTAGMEASGTGNMKLALNGALTVGTLDGANIEIRDAVGPENFFLFGLTADEVIARRCEHFEGRDAVAADPELREVVDLISSGFFSPEYRELFQPLLDRLLGRDEYMMLADFKAYSACQREVEAAYADRKSWLRKSALNIARVGEFSSDRTVREYARDIWGLTPVEIDVGAAKSLL
>NC_021658|7627900:7712487|7631561_7632053_-|WP_187345638.1|DBSCAN-SWA
MIVIRCETGDDVKVDADSLVGINLSRMNLHRALLEGQVLRGADLSESELRSAWLEDACLENAKLTRARLAACNASRASFVRADLRDAMMRSGGFEEADFSGADLRGAKVEGATFARAILLGADLRCEGLERAELAGARADTLTRWPDGFDPVSRGVSIQSAVD
>NC_021658|7627900:7712487|7632052_7638505_-|WP_020737247.1|DBSCAN-SWA
MLALVACGTHERPAAERLGLAASASTGGERPTLPEPLDLPQSPILSGDEVGYLPGAGQVTADGAYIYTIPLDVPPGLGVTPELALRYSSRGGNGPVGRGWSVAGSSSAIARCDTTIATEGHADGPDYDATDRYCLDGKKLVAVKGFDGRAEYRTEDDEMSMIRALGGSSRSGPGAFEVRTKDGRIRIYEETYATRVVTRGKVEEPAGVVRPLWLLARERDRSGNEIEYLYEKHGSTKPPYSHEFLIETIAYGPGSSPRRKIVFEYEDRPDPSISYGGGIGWRSTKRLKTIAMWAPNPVSTQKVWEYTLDYEMGQLGRSLLSSVQKCGHQGTCLWPKRLHWIHEDPLLFAGGPVLPISGDITSVRVFDANGDGRDDILHAVDVPTPWSPPPLPGHPHPPVPPEPPDQLFLSLSEPGSEVSFRTLHVNPAGSPLEEVNLKHSRPVDADGDGKVDLLAYDTGACRYRLVAWSDESEAFVATGATISGGKARVCSGKFSASAPALELVDLNGDALLDVLVEFAQSVDESSWSILMNEGGRFGDRIVTGVRAAPRPCEAVGGDLDGDGRGELIVGEDESCEAGVAIGLDDAGEVTTGPAFPLKRGGVPATLADINGDGLSDALWVDVDAGSVWLSMNTGNGLRPVVTLPDPGVAEALALEAGGLVVEPFDLNRDGRDDLLVSISDWLNPVPPAGRFTDLILAFLSRGDGTFLRQEIGWEEPETGTHYSPLPAGGAMWHGDFDADGRADVLTRRANVLEVTRAIGKDVELLSGVSDGDEPRAYRAHVRYGRTNPSSSPRDVCTYPLRCVYRGAPVVAWVGGLERPGGTSYRFEDPRADLLGRGSLGFERMIEWSGAWPVERITAFDNETRVGTAYPFAGRPRWIREVTPIVPHGPLGARDCDPLTDGSCTIEEGPASARARVVEQEIDYRVVGLNEGRSYLVSVQGTLRREYEDPEVDIDWAEGVRLHCPDVDDPGDAAPIRQSATYEVDDHGNVRRSIVETARGVRREVTRTFDVRPDEWLVGLIDTHTERVYEAGATVPGKLHVDYHHDERGLLDEVKIEPDSTDPDVRETISFQLDEAGRLIEEKREAAGESPRIWSYAHDDVSGEGIFVSQVWNGLGVSHWTYTHPAYGVLMGEIDANGAWSTRVHDDLGRLKQARSGAGASSETTMAAWVEAGETAGLVVETTLASGGSAVVTLDERGLAVKEAERAFDGRMKVRGRSYDVFGRPLSASRPGFDVAAEERAERTYDSLGRVLSETGPDGTQQWYEHELLQTIGIDPEGRRSRTIVDVEGRPSETAVEVDGAWQPTQFAYGLHGKLWKVIDPKGNTTEMAYDIRGRRIEVRDPDAGVRRTRYNGFGETREEVNALGQRTVVERDAMGRRRVVTSADGATTFTWDKAEHGVGQLASALSPDGTEVLTTYDAQGRVSEVWTAIEGEAFSVGVTYTPDGLRDELLYPKVPGRDRFRVKHVYEDGSLSELRASQEDGTTRSLWKVNARNADGALLEATFGNGVRAERTYEPMTGRLATVEAKTNASLQALTYGYHDDGRVRERRDGVALRVETFGYDEAGRLERWELAAPGGARGTTYGYDELGNLRTVAVDGVVAEENRYEPGGRPRIVAGRDAVTFSHDAAGRLERSSAGLWIAYTAFDLPRRVEKEGKSWAFLYDAFGARVKKKHEGEETVYVGGVYERRTDAGGTRHVFRVASPEGEVAQVVFAGPRKEQTLYVHADPLGSVGLLTDEAGEEVERLHYEPFGRRIDADGKAPGVAKSEVKHGFTGHRHDDELGLIDMRGRVYDPSLRRFLTPDPLVTDPLWGQSYNRYSYVMNDPVNLVDPTGFYWERVSFDNGGWGYAEYDDTTGELKGIWDATEEVVTAPGAPTPPSGEVGPPQPPGGAEERGNPEFESDWASFIHAGDEYFEQRGGSSVGDEYSGAGETLAAVLERGVRLSDLTGEKSTPGLVSGSVMGDLVILPSFSWSAAVARDFHEALELGALAWHAGNDAEAFMQDLRAAMDVAALGVTVAVESGIGPAMVLGAVLPKLGGGAVVPEVATGGRATITSGSQVTEQVIREAMKDAPLASQQARGVSLPLVQQYVDKLIAREVAPAIKVDGRMIVDGNHRYIAGRVFGQEPAIQPWAGGRPERLVPWENLPINPESW
>NC_021658|7627900:7712487|7648579_7649809_-|WP_148313906.1|DBSCAN-SWA
MIPPKFMEPTFRRAFNAAFGPSTYAEILSRLERRLGCAIPFRVAETPLFLPARLRERLERSATEIVQQISSPALIAQMKRAIPAHLDAPGMDALPNCAQVDFAIVRGPDGELDVKVVELQAFPSLYALMLVQTEIVAEVLAGMPGLDRRWTCCFGGRSRDDVVAHLRRAILAGEPEESVVLLDLSPEKQKTYPDFMATKLLVGVDAVCPTALVREKDRLFRRVGGRLVPVRRLYNRVVFDELEAKRVELPFRYDEPLDVTWCSHPNWYWTWSKYTLPYLDHPAVPRARLLSALDEAPPDLERYVLKPLFSFAGSGVKVDVTREDIAAIPEGERSRWLLQEKVAYEPALLMPDGGGVKAEVRMMFLRAPGEPELSLALNLARLSRGKMLGVDQNRDLTWVGGTVGIWPVG
>NC_021658|7627900:7712487|7709308_7709497_-|WP_148313908.1|DBSCAN-SWA
MSRSGQEVRELHLSVTVDEVNLILEGVGLLPFARVYALVAKVQQQASQQLGGKPAQEEPDAT
>NC_021658|7627900:7712487|7711843_7712008_-|WP_187345640.1|DBSCAN-SWA
MPVEIKELVIRAVVAPPEGAPRARAAAPDAAGLEAVVEAAVKEVLRVLKASKER
>NC_021658|7627900:7712487|7673615_7679384_-|WP_020737271.1|DBSCAN-SWA
MSAVSRLRFAPAALAAIALSLACVQGARAPNVPPRGTLAPGALDPGGRPAEGPFAVVFGAPRGQTTSPAEISLVFNRPMRPLDLAGGEAAAPAILKPPAPGRWRWVGTSGLTFAPDGHLPRGTAFTVEVPAGTRALDGSALEKPYVLSFRTALPKVARVEPWSGKDDLRPDARFELRFNQPVDTAEVARSVSLTAGGRAAKVAFDVRRPDPKNELLAEIVPRAPLPRDSEVELAVAASLRGREGPLPAGEEQRFSYRTYGPLRVVRTDCDRDTPQGACATEGGFSLAFSNPVRLADAKRAISVEPAVKLRWPGWLEDESFTSHIHLGGAFAPGRSYQVRVAAGLRDQHGQALAGAATREVAFGDRWPEAQIGLTGSVFEPAQRREIPVVSVNVRELSLAVGAMTEEAVLALEADPHSPGRSPKMDEIAALPAGKRSVLRPAAATNTPSTHLVRAGEVLGGEGKRGPLAIGISYTARPGTRHARTASEAVIAQVTDLGISAKVSPNGSLVWVTRLSTGAPVPGASVWIRTPDARSPAAVVTDADGFAVVPAAAYRPSTASGPERGVIFARSGDDWTYRRVADALSGWRFGAPSDFGEARPFGMVFSDRGIYRPGDTVRVKGIFREEAARGTRTPAGRRVAFKVEGPDGEALVTLSPSLSAFGTFSADVKIPETARLGTYSLAATVQGGDAGWPDVTGSVEVAEYRPAEFKVSVESDRPSYVRGDKARWIARGDYLFGAPMTNAEARLSVTRAPAAFSPPGIEGFTVREDELTDALPDRAPREFEVQSGREKLDAAGQAAIGAALALPGQRGTESVTCEAEITDVSRQAIAGSSTALVHPAEFYVALKEPDRFAKAGDVLRPEILAVDPKGARVAQVAVRVELVQRTWTLAREESGSAYRSVSAPVDKVVARCGVTTAAAPRSCELTVPSGGYYLMHATAKDRRGNPVGAAAGVYALGEGGGGFGDSDQLQVELVPDRDSYEVGQTARVIVKSPFASADALVTVERAGIASHRRVRLSGAMPVIDVPITDDLRPNAFVSVLLLRGRTKPPPAPGKGGAPGPDVGAPAFRLGYAPLRVNPEAQRLAVRVVPDKVDARPGDPIRVDVDVRDRAGRPARAEVALYAVDEGVLSLTGYETPDPVPVFGAPRSLRVATVETREALARVRNPFADLGADKGRAGGGGAQGGTGVRRDFRQSAYYHPAIVTDAAGKVSASFKLPDSLTTYRVMAVVAAEDDRFGYGESRVTASQPLMARPALPRFLRAGDAIDAGVVVTSKGLGKPATVEVEVAASGLTLQGAAKRAVDLAPGASAEVRFALSAPRAGPATLRFRASGGGASDVVEVTREIRAPMSPEAVALYGDTTTASAEKLGDLSAIRDDTGGLTVSLAPTALVGLGGGVEQLLEYPYGCTEQLTSRMVPLLSLRDLAKAYGIALPKDLTAVIGKTVREILSHQRGDGGFGFFAESDRADLWTTAYALWGLGEAKRHGVAVPADAVERATSFVRARLNEADDDPLLRATSPFILDVLAEIGAPDPGRASRLFDEREELPLFSKALLAHAMVIGKSDRAAVDQLVGELEGALRLDGPIARAVHNHGDAYAVLMDSEARTSALVLRALLAARPAHPLAARLAAGLLADRRGGTWRSTQETAWALIALDQYRRAQEKAAPDFEARVFLGQAELFSAPFHGPTTEQVKTSIPAARLASAGGAPLAFTVDGRGRLFYEARLRYARKQLPTAGLDRGFYIEKSLRALAPEDLAAALGGAPPAAGSGAAPSSLAFAGGDLVLGEILVVAPSPRDFVVIDDPLPAGLEAIDARLATSARSLDVDAAEAQADTDADADVDQDDLRATGRAYEPSRFVREVRDDRVLFFVDHMAAGMYRYRYLARATTLGAFVVPPARAEEMYSPEVFGRTGALAVKVGSRDAAPRPR
>NC_021658|7627900:7712487|7662399_7663701_-|WP_020737266.1|DBSCAN-SWA
MSSTRDATRARAVQWFVRGGTLRAAGRDPVKIGIAPVVVGRDPSCDVVVDDPEVSSTHCELRAEGPGVLVRDLGSKNGTFVSTVRIREAILTAACAIQVGGSVLGFEPLDKERVDVGFDESFGPLIGASPRMRHLFRLLREVAATELSLLITGETGTGKELAAQAIHDSSSRRGGPFVVVDCASLPGALAESFLFGHERDAFPGATERKGGAFHEANGGTIFLDELGELPPELQPKLLRVLSERKLKRVGSRVYEPVDVRIIAATRRDLGRSMNTGRFRSDLFFRIAQMRIELPPLRERREDIPLLVESVCARLGCPERSVEMVNLITTTLGQHDFPGNVRELMNVTSVAASLPPGAEAIAAILPLEGGGDVVAPTSAFGEAKRSAVAAFEQRYFSELIRATGGNVSEMARRAGMERHHVRMFLRKHGLTAKP
>NC_021658|7627900:7712487|7627900_7628491_-|WP_044988776.1|protease|DBSCAN-SWA
MRFDATPNEEQLPHRALSEEVQSSLLRSRTVLIFGEITSELAQATTAQLLALANQSEAPIRVLIHSPGGHVESGDTIYDVIRFIRPEVKVIGTGWVASAGALIFVAARRENRFALPNTRFLLHQPLGGVRGPASDIEIEAAQIMAARERLNRIFAEATGQDPAKIAKETERNLWMTAREAQEYGLVHRVVESALEV
>NC_021658|7627900:7712487|7651881_7652844_-|WP_020737257.1|DBSCAN-SWA
MLVTREEMAFDFQGAKLDPVKDKDVIVWAVQQFLYGEITGVQIGHWLYNAPDLESARFLARQAVEEFQHVGNFLRILEILGAPPEKAAWSVRFLATGLMGGDWSEHVALEMALGEGLVLQAFYAMIDTVDEPEIVAILKRGVRQEERHVDFGEQQTRKAIAGRPALRRRLLGLALVSLWGVSRLEAFMKKRLPMDHPALRRLPDLVRHSVRIAELRLMRIGLTDAPISSMSAARKLALVAEAYAGKLALGLASWVLSVLLLPLRLLGLAGPKRLTDTYLRDPLVVRGGRLGAGAEDDPGDAGEQAGPGGPSAGHGAAARA
>NC_021658|7627900:7712487|7656423_7657482_+|WP_044986198.1|DBSCAN-SWA
MSSSPLGFDPNGPAVGHGIYGLPHTAEDARVVLIPVPWEPTVSYRRGAAKGPAAILRASRQIDLFDLHTGRPYEQGIAMLDVDPDIVRWNAEACAAAEPVIAAQGEVAGDRDLEARLAAVNALSRRLNERVAEIAKRWMERGKLVGLVGGDHSAPYGTIAAHAERYPGMGILHVDAHADLRDAYEGFTDSHASIMRNVATRHPKISRIVQVGLRDMSEDELRFIRESNGRVVAHVDAAIADRLFEGEPFHLIADAIVEDLPDDVYVTFDIDGLDPTLCPSTGTPVPGGLSFQQAVALIGRIHRSGRRIVGFDLNEVAPKDDHDEWDGNVGARLLYKLIGFTLLSQDNAQNNR
>NC_021658|7627900:7712487|7690454_7691810_-|WP_020737278.1|DBSCAN-SWA
MRTLIISDLHLGNGGDYDVFAGGEALPALLDRIAGEPARVVVNGDGVDFLMNEDPLELDPARAAAQARAIAAAPASAAVLEAFGRVLARGGEVIVRLGNHDVELAVPEVQEILRAAMDQPPEVAARLTFQLGDAPAILDVGGARILVTHGEHNDNWNKVDYGRLARLDRFRYAAGSVLVKQLMNPIARRHGMRFVSLLKPDFQGAALAALAVAPGIVKQLFSAASLDIAWQLFKKAGSAASFAEEDEDLGLAERFADAGLEAEEAAAIEAALGDGPAAFADEETMSTASLKLARAGLKLYAGMQKRLAGTLGDEYFRLEPDEAEWADARRLAKKFDAGAVVLGHTHAARWKVADGIAFANTGTWIWLMQLPRSDAGDEAWAEFLEELRNNPRLLPERQRAAKTVRRLTAVLVDPHPDGGATMRLVQWDDGELRSLEAARVPPGGAAPGREA
>NC_021658|7627900:7712487|7686890_7688159_+|WP_044986202.1|DBSCAN-SWA
MELTDDSRSRWLGRYEALRAIRRRDGFHVVAATRAGDAEPCVVIVPGPAVSAARAKTVFAEIERVHALLDHPLIPKVAARGVADGMPYIELACDAVIDGVDLTSLLNDAGWRLPPGSAAGLVASLRKAMRAAHAVIDPKHGRPVCIGRVSCADVLFSREGRFYLVGYGRDAPLERAGGQEIDRVLEFQAPEVAAGGDPTPAGDELALSLLARSLRHAVQGSAASARGADRNIRSMDLEPPEPLERRAPFAPAHARRCAEEMDLRHHLAPCSEAPDPEGFASLVASLLAGRPLPLAAEAAPTCPPTLVLGCEVRWITAEDGVKHTLGHALSRIVTALVDRHDEAPDAALSLQDLFEAGWPGERPVANAGANRVYVALTQLRRMGLRDVIERNEHGYRLAPRAVVRFVSPRTEHARPQDTRSAP
>NC_021658|7627900:7712487|7691852_7693073_-|WP_020737279.1|DBSCAN-SWA
MTAEKSDDGAPPLAGVPAWVDMDPAPAEPPEEWLARPVAFADDEPPPQLVRTVNLLDPPEHGLRGPEDAEGLAAFLLSRAREGIGDVFSHPDYDTASGDREDWARAIAEHQTGIPYTMPAFFYGGQRGVAKAISGSGRYPIVGQCQQSVTTALCIGGWDGGPYGDIGCGTDALPAAARLGDGWTSVPKVLADWPDDLWEKVTVGSCLFWSASGAAGAGSGHVAMVIRKHPVERKWQLWDTTTSFNDPAVHAAAGRGARMLWESHWWPFIPPALCGGRWSFRGIARIDGLGEIKSDLKPRGRARLLLRRRGDGALLYRSEWMSMEDEGLPISWLLRSLRGAPFHDRIEPTWCVNSKSDAPTKLAPDNRPLLDVFCDAKGNAKMSWSPAQGLHNRPHQAIWAAPAALR
>NC_021658|7627900:7712487|7664093_7666439_+|WP_044986199.1|DBSCAN-SWA
MPRTGWYLRKRAATALGLLGLTAGAGALAAGSSGCTGDAGGPCISDEQFFAEKVWVPILSTKCIGCHNPQGQAAKSKLILAGSSEAGFLDKNLATFKSLAGLELSGESYVLLKPTKKVDHGGGHVIDADSADYEALREMVDRTKEPSSCETDVNASFAGVVMSGPEDTLRAAALEIAGRLPTEAEAQAVAQSGMDALDPILDQMLTEEAFYVRLKEIYNDLFLTDRYLNGEAAVDLLKSDAYDAKWYNSLPQDPALVEKYGARDLEDAINKVKSWTNRGVGREPLELIAYIVRNDRSFKEVLTADYTVVNPFSAKAYGVTAEFQNDADPEEFVPVKRDPIPLAGVLTSPVFLNRHPTTSTNRNRHRARVVYQYFLGTDILKTAEQPLDQTKITDFNPTMNNAACTVCHAALDPLSGGFHSFDSAGRYEADDTWYEDMRPPGFGAESVPFSEFPSALSWVAQRVADDPRFALAAVYTMYTGLTGQKPLVAPTNDDPEFSAKFRAYLAQYHAFNAMAHDFADSDYNLKTVVKAIVKSPYFRARNVAQASSQGDPLAQLGGTRFLGPEQLHRKIWAVTGYPWRPRAFEDDGNRYDYLLRRDAYRLLYGGIDSEEVIQRITEPNGIMANVADRMANEMACISVPRDLWLPQEERLLFPFVETTFEPRDTNDFDVLPAVEAIKKNIQYLHERVLGESLEIGDPEIERTYKLFVETWEEGKAGMKKPEGEEGRISTWLPGPCEVENDYWTRDALPNEEKLQRDENYTIRAWMSVMTYLLSDFRFLYQ
>NC_021658|7627900:7712487|7661492_7662191_+|WP_148313907.1|DBSCAN-SWA
MRAFLALLTSSIVVGLAASGGCSSSPAADATSTAAAATVAGAGGSLGFGCFGGSPDGRCTILAQVSEDCGCPDCADSASCLGFCKDDGACDLRPDAPDGEDCTCQDCANSVAECSPSRGCNSNMGCNANEDCTCPDCTDTPRCTDHCTDNGSCAPYFEGCSCADCRSAERCGGGGPATTTAATTGGGEGGGGGGAGGAPAGTGGSGEAGGPAGTGGAGGGGGAPGTGGAGGA
>NC_021658|7627900:7712487|7699291_7700884_-|WP_020737283.1|DBSCAN-SWA
MSTARPIDVRCARDRLIDLLGLGETTPIRDVNVQEAQLTVNVGAPCEITIDPAQLGVRYELFDGDAAVVPACSVDGTGEKAILEGPIIDKADKTFRIFARKLDPLTRETFLIQTATVKVGLATDLPVSTPEIAEVPRLVDHGSRVVVSVSGSQAGATYGLIDGAGRPIPMTPPGRVSGNKDGAITLTASRVTEDTVIRVDVQRTFDEGEGRAPLHAVLAAELPIAVRAARDLAVSAVGSPVLPQGSATITIAASQTSALYSAHVRALSTVDFVPGAGPTERVIAVPGTSGVEVYTPRPPALWQAPAGSAQHGDAAPGNGGVLELGVGPLLDDSIVVVQARKIHTAAGAPLESAVQLEQAAVVLVRPEPAPPLVLQIAPNADNASGTLLVSGGQPGVFYHFYPSNEAGALGLPAYFHRRDERDPSMNKGVAATEPEAADQVPRRGLRVEMDLVVTRDPPAPAALDPAHVRPLDPLVDIAPLPLGGAVDVMAIKARTGIGWVAKRSVAITQVTDGSSPSEQGAAPEPAATEP
>NC_021658|7627900:7712487|7684716_7686711_-|WP_020737275.1|DBSCAN-SWA
MWLEIELDISGDEVRVNARGSRGERPAGHAIAAEQGLGALQTFANKIGRAVRGGKSLDPAAVSDSQALHEEVFKGELRDVLVRLGEASKGGPLLLRLFARDHALQAIPWEALCRPGTSEGFLGTDPRVLFARGVTSSEPWEPREVKGAVRVLGIAPGTGERALDVLREALAPSIDAGEVEWLDPIAGPDIGARALFDRLRRGKSPHVVHWLGHGGVDLSGKPVLRVSDDEDGEEAWITAEALGRELSAAFCEELRLVILEACEGARAGALGSAAEILVRAGADAVVAHLWPVKADVARACSTELYRALTGASLGQGDIGASVAAARRTLLSQSAEAFSPILYLRGSDSVVFNFQGRRVARPGKKGRSRALAPALQSLLERPFTMVLGDLEDDRAALQRELEQFMQESGEPAAQGMSLSALTQRCVLRFGQEVLHSLFQQALTASPAATAPPLVEALARFVRPGVHVTLLWRPCLEHAIAQKLPQRTVYAIQPSLLGASGKPRVVKRAAGTATWKMDAVMPRRFDLDSEIVVLRLYGGYSAEPRPIFSPPLLTEDDHIHGPLGADGARPPLWMEELLARPRVQPGLFVALSSLDFRHRMLLRWLYDQRPAPPDSLAVLAPGVEGSEIEIWGNGGGLPGTGHIAATTGDLVELAEQLDAFALEDAS
>NC_021658|7627900:7712487|7649942_7650575_+|WP_020737255.1|DBSCAN-SWA
MIKLRSAMVLPLVAALAAACSKTPEPTATSAPEPPAANTGAAPAPTTQAPKPAHPGGQQAAGAELAWDAPASFESAPNPNAMRKATYKIKRAAGDTEDAELSVMPAGGSVDANITRWVGQFSQKSDDSPKRTDLKVNDIKVAVVEIKGTFAGSGMPGMPAGEPKSSYAMLGAIAETPSGDLWFFKMTGPEKTVTGARADFDKLLNSLRLK
>NC_021658|7627900:7712487|7688185_7688761_-|WP_020737276.1|DBSCAN-SWA
MRTPEEEPDAPPARPPAEAAGEAPPRRARRRLALRSRRRDRVAGVDTSSRLLREQLWTLALLALLVLLLLVALTATARAPVQQWPAWGTRTLLGVFSFGALGATFSAARSLKGSSRRARAHARVSDARVTLSRAVLGALPGLAAYAFLQSRVLNLGDADNSKAFAIAFIAGFSERLVLKVAETFAGEQRAR
>NC_021658|7627900:7712487|7709493_7711119_-|WP_020737290.1|DBSCAN-SWA
MPAVTPTILSDGKPMDPAYELLSIDIRREVDRIPRAELRVLDGDAAQQAFAVSDTGFFAPGAKIEIKLRYEGEEDRCVFKGVVVRHGVEAGHDGSVLVIGLKDAAVKLTGARRSAVFRKMTDGAIVKQLIEAAGLEVGTIAETRPEHAEMVQYHAAPWDFILSRAGALGLLVVVEDGKISLRKMAVEGAPRHRFAYGITEIFDVEIEVDAEHQYRAVESVAWDVKEQKPTAASKAKSLRATQGNLDGGMLGDAVGNGTCTLSHPVPVAAEELQAWADARMARSRMALLRGRIAVPGFAGIRPLDVMEVAGVGERFNGTTLVTGFRHRVDASGWRTDVQFGLSPEELSRKEELREAPAAGLLPAVSGLHVGVVAEFEDDPDEELRVKVILPGVDAKQDKAVWARLAAPGAGKARGYFFRPEPKDEVVVGFFNDDPRRPVILGALFGSKNAPPEAMGKPSKKNDKSGIVTKFGTKIQLLDPDEDKASVSIETANKNKLLIDDGAKSIVLSDQHENSITMGKDGIEIKSEKGKVTISGKGVDIQ
>NC_021658|7627900:7712487|7628617_7629550_+|WP_020737245.1|DBSCAN-SWA
MADETERQLPRGVAVSRHHGPPGVVWRASAGDPPSLHVVVQGAFRLAQDGACTLDGACALELDAGDLVLLGFGARGAGPGEQRLCCVAPPTGAAPAAAEVISATYAAAPGGALASLAPLVHLPAGEVRRAPGLSAVVGLLRAALADPSPGQAALARSLLEPLLAYALHCHERAGEAGAARARGRCVARAFDRRVARALRLMQERPAERWTLEALAKAAGLSRAALARRFLAELGVPPLRYLAELRMQRAAELLAEGDGSLASVAAEVGYDSEFAFSRAFKRHTGEAPGAFRRRSRSEGAAFRLPPVRAAA
>NC_021658|7627900:7712487|7654659_7654980_+|WP_020737259.1|DBSCAN-SWA
MDEERQRKIASKGGKAAHEKGTAHEFTRDEARAAGKKGGEVVSQNRKHMAEIGRRGGERVSQDRAHMAEIGRKGGEAVSGDRQHMAEIGRRGGESRGDQPRENQPR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044988776.1|7627900_7628491_-|protease	ATP-dependent Clp protease proteolytic subunit	A0A248SJ97	Salicola_phage	5.4e-28	40.6
WP_020737245.1|7628617_7629550_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_020737246.1|7629635_7631285_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_187345638.1|7631561_7632053_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_020737247.1|7632052_7638505_-	VCBS repeat-containing protein	S5W9C6	Leptospira_phage	8.6e-10	35.6
WP_020737248.1|7639136_7640003_+	hypothetical protein	NA	NA	NA	NA
WP_044986197.1|7640304_7640904_-	hypothetical protein	NA	NA	NA	NA
WP_020737249.1|7641106_7643677_+	glycogen/starch/alpha-glucan phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	9.3e-16	50.0
WP_148313905.1|7643883_7644282_+|protease	ATP-dependent Clp protease adapter ClpS	NA	NA	NA	NA
WP_020737251.1|7644278_7646615_+|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	2.9e-165	42.4
WP_044988779.1|7646916_7647300_-	Co2+/Mg2+ efflux protein ApaG	NA	NA	NA	NA
WP_044988780.1|7647751_7648570_+|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_148313906.1|7648579_7649809_-	hypothetical protein	NA	NA	NA	NA
WP_020737255.1|7649942_7650575_+	hypothetical protein	NA	NA	NA	NA
WP_020737256.1|7650671_7651844_-	pyridoxal-phosphate dependent enzyme	NA	NA	NA	NA
WP_020737257.1|7651881_7652844_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_020737258.1|7653061_7654147_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	2.8e-83	44.4
WP_020737259.1|7654659_7654980_+	hypothetical protein	NA	NA	NA	NA
WP_020737260.1|7655086_7656031_-	fatty acid desaturase	NA	NA	NA	NA
WP_044986198.1|7656423_7657482_+	agmatinase family protein	NA	NA	NA	NA
WP_044988781.1|7657521_7658817_-	M18 family aminopeptidase	NA	NA	NA	NA
WP_020737263.1|7659143_7660283_+	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_020737264.1|7660272_7661433_+	N-acetyltransferase	NA	NA	NA	NA
WP_148313907.1|7661492_7662191_+	hypothetical protein	NA	NA	NA	NA
WP_020737266.1|7662399_7663701_-	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_044986199.1|7664093_7666439_+	DUF1588 domain-containing protein	NA	NA	NA	NA
WP_044986200.1|7666447_7667722_+	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_187345639.1|7667782_7668763_-	DUF4263 domain-containing protein	NA	NA	NA	NA
WP_020737269.1|7668759_7670895_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_020737270.1|7671098_7673612_-	penicillin-binding protein 1C	NA	NA	NA	NA
WP_020737271.1|7673615_7679384_-	hypothetical protein	NA	NA	NA	NA
WP_049949634.1|7679749_7681966_+	two-component sensor histidine kinase	NA	NA	NA	NA
WP_020737272.1|7681962_7682592_+	response regulator transcription factor	NA	NA	NA	NA
WP_020737274.1|7683020_7684694_-	hypothetical protein	NA	NA	NA	NA
WP_020737275.1|7684716_7686711_-	CHAT domain-containing protein	NA	NA	NA	NA
WP_044986202.1|7686890_7688159_+	hypothetical protein	NA	NA	NA	NA
WP_020737276.1|7688185_7688761_-	hypothetical protein	NA	NA	NA	NA
WP_020737277.1|7688763_7690455_-	hypothetical protein	NA	NA	NA	NA
WP_020737278.1|7690454_7691810_-	metallophosphoesterase family protein	NA	NA	NA	NA
WP_020737279.1|7691852_7693073_-	hypothetical protein	NA	NA	NA	NA
WP_049949635.1|7693069_7694785_-	peptidoglycan-binding protein	F8TUT3	EBPR_podovirus	9.9e-06	51.5
WP_044986203.1|7694883_7696170_-	hypothetical protein	NA	NA	NA	NA
WP_080682310.1|7696350_7697706_-	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_020737282.1|7697783_7699295_-	hypothetical protein	NA	NA	NA	NA
WP_020737283.1|7699291_7700884_-	hypothetical protein	NA	NA	NA	NA
WP_020737284.1|7700888_7702880_-	hypothetical protein	NA	NA	NA	NA
WP_020737285.1|7702945_7704160_-	hypothetical protein	F2Y385	Organic_Lake_phycodnavirus	3.1e-22	38.1
WP_020737286.1|7704230_7708445_-|plate	baseplate J/gp47 family protein	NA	NA	NA	NA
WP_020737287.1|7708460_7708895_-	hypothetical protein	NA	NA	NA	NA
WP_020737288.1|7708902_7709319_-	GPW/gp25 family protein	A0A060AMS0	Cronobacter_phage	7.0e-06	27.1
WP_148313908.1|7709308_7709497_-	hypothetical protein	NA	NA	NA	NA
WP_020737290.1|7709493_7711119_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_020737291.1|7711124_7711847_-	hypothetical protein	NA	NA	NA	NA
WP_187345640.1|7711843_7712008_-	hypothetical protein	NA	NA	NA	NA
WP_044988787.1|7712010_7712487_-|tail	phage tail protein	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_021658|11179203:11248868|DBSCAN-SWA
TATGCGATCGATGTCTTCGATGCTGGCGCGGTTCGTGCGGGTTCGGGTGCCTTTGCTCGTGTGGGCGCTGGCCGCGGCCGCGTGCGCGGCCGAGCCGCCGCTCGACGGGGAGGTAGGCCCGGAGGCGGCCCTCCTGGGCGAGCACGGCGACGCGCTCTCGACGCGCGTCCGGCTCATGGCCGCGAACCTCACGAGCGGCACGAACCAGAGCTACGATCCGGGGCACGGCCAGCGCATCCTGCAGGGGGTCGAGCCCGATATCGTCCTGCTGCAAGAGTTCAACTACGGCAACAACTCCACGTCCGCCATTCGCGGCTTCGTGGACGCCACGTTCGGCACCGGGTTCAGTTATTACCGCGAGACCGGGGCGCAGATCCCGAACGGGATCGTGAGCCGGTGGCCGATCGTCGCGTCTGGCGAGTGGGACGACGCGTCGGTCGGCAACCGGGATTTCGCCTGGGCGCGGATCGACATCCCCGGCCCCGCCGACCTCTGGGCGGTCAGCGTCCATTTCCTGACGTCGGGCTCGGGGGCGCGCAACACGGAGGCGCAGCAGCTCGTCTCGTTCATCCAGGCGCACGTCGACCCTGACGATTACCTGGTGATCGGCGGCGACTTCAACACCGGGGGCCGGGACGAGGCGTGCGTCACGACCCTCTCGAGCGTCGTCGTCAAGCCCGGGAGCTATCCCGCCGACAAGAACGGGAACGACAAGACCAACGCCAGCCGGTCCAAGCCCTACGACTGGGTGCTCGTCGACAGCGATCTGGAGCCGCTCGAGACCGCCGTCGTCCTCGGCGGGAGCAGCTTCGCGAACGGCCTCGTGGTGGACACGCGGGTCTATTCTCCGCTCTCGGAGATCAGCCCCGCGCTCTCGTCGGACAGCGGCGCCCCGAGCATGCAGCACATGGGGGTCGTGCGCGATTTCGTGATCCCCGACGGCAGCGGCGGCAGCGTCAGCAGCAGCAGCAGCGGCGGCAGCGGCGGCAGCGGCGGCGCCGGCGGCGGCACGGCCAACGTGATCATCAATGAGGTCCTCGCAAACGAGCCGGGCAGCGATCCTGACGGCGAGTTCGTCGAGATCATCAATGTCGGCACGGCGACCGCCTCGATCGGCGGGTGGAAGCTCGCCGACAGCACGGGGACGCGGCACACCTTCCCCGCCGGAGCGTCGCTCGCGCCCTCCACCGCCGTCGTGGTGTACGGCCACGCCTCGGCGGTGCCCGCCGGCGTGATCGGAGCCGTGGGCGCCTCCACGGGAGCCCTGGGCCTCAACAACGGCAGCGATACGGTCACGCTGCGAAACGCCGCGGGTGCGGCCGTGAGCAGCGTCTCGTACACGTCCGCGCTCTCGAATCAGGACGGTGTCTCGATGAACCGGAGCATCGATCTCGACGGGAGCACATCGTTCGTCCTCCACACCACGTTCGGCGGAAACTCTTCGCCGGGCACGCGCGCGGACGGCACGTCGTTCTAGCCCAGGACACCGAACGAGTTGAAACGTCGGCGCGTTCGCCGCCGGGGCCCGCGCGAATGACGCCCGCGGAAACCGCGGCGCTGCTCGGATCACTGCGGGGCCTCTCGGGCATATAGTCTGACGACGATCGGCCGTGTGCTTCGGGCACCGCCGCGGGTCTGCACCCAGGAGCGAGAATTCTAGTGATGAACAGGGCACGAGGTTCGACCACCGCCATCTTGCTGGCATTTTTCTTCATGGCTTGCGGTCCTTCGACCAGCGCGACGGAGCCCGAGGGCTCGGGCGGCTCGGGGTCGGGGGCGGGCGGCCCGGGGTCGGTGGCGGGGAGCTCGACGAGCACGGGCGGCTCGACCGGGTCGGGGGGAACAGACGCGAGCGCCTCGACCGGGTCGGGGGGCGCCGGCGGCGAGCCGCCCGGAGACGGCGGCGCTGGCGGCTCGTCCACCGGCGGCGGGCCCCCCGTCGTCGAGCCCACGTTGATCACGTCCGGTCCGAACGATTACTGGAAGACAGGAACGCCGACGGAGGTGACGAGCGGCAATGCCGATGTGACCGTCGACGAGGCGACGACGCACCAGCGATGGGACGGGTTCGGCGGCACCTTCAACGAGGTGGGCTGGAACGTCCTCTCGATGCTCGGCGAGGCGGAGAGGGCGCGAGCCATTGAGCTCCTCTTCGACAAGCACGAGGGCGCGGCGTTCGCCTACGGGCGCATCCCGATCGGGGCCAGCGACTACGCGATGGACCGCTACACCCTCGACGAGACGCCGAACGACACCGCGATGGCGAGCTTCTCCATCGATCGGGACAAGGAGAGGCTGATTCCGTACATCAAGGCGGCGCTCGTCGTGAGGCCCGGCCTCCACCTCTGGGCCAGCCCCTGGACGCCGCCCACCTGGATGAAGAGCAACGGCGCCTTCGACGGCGGCCGCATGAAGGACGACGCGAGCACCTTGCAGGCGTATGCCCTGTACCTCGCGAAGTTCGTGGAGGCGTACGCCGGAGAGGGCATCACCATCGAGGCGGTTCACCCCCAGAACGAGCCGAACTACGAGACGAGGTACCCGAGCTGCACCTGGACGGGGGCGCTCATGGCCAAGTTCATCGGCACGTATCTGGGGCCGACGTTCGCCGACCGGGGGCTCACGGCGCAGATCTATCTCGGCACGATGTCCAACAACGAAAGCGGGAAAGACGGGGCGATCATCAGCGCCGTGACCGGCGACGCCACCGCGATGGGGTACGTCAAGGGATTCGGGCTGCAGTGGAACATGATGAGCAGCGCGTCCGGCTTGAGATCGCGCAATCTGCCGATCGTGCAGACGGAGCACAAGTGCGGCAACTACCCCTGGAACCCCACGGGCTCACCGCCGTTCGACGCGCAGAAGGCGCCGAACGATCACGCGTACGCCGAGGAGAGCTGGGGGCTCATCCGCGACTGGATCAAGGCAGGGGTGACCTCGTACAGCGCCTGGAACATGGTGCTGGACACGGCGGGGAAGAACCTGGACTCAGAGCGGCCGTGGCCCCAGAACGCGCTGCTCACCGTGGACACGGCGGCGAAGACGCTGAACGTGACCCCCGTCTACCACGTCTTCCGCCATGTCTCCGAGTACGTCGATCCCGGGGCGACGCGCGTCGCCACGACCGGCGGCGATGCGCTGGCCTTCAAGAACCCCGACGGGAGCATCGTCACGATCCTGTACAACTCCGGCAATGCGGCGAAGATGACCGTCCTCGATGTGGCCGGGAAGAAGCTCCAGTTCAGCGTCCCTGCCCACGGGTGGGCGACCGTCAACTGGACGTGAGGCCGGCGCGCCCGCGCTCGGGCCGGGTCACCGCGCCGGCTCGTCGAGCAGCGCGCGGACGCGCCCTTCGACGGTCGCGAACTCGGGGGTATCGGGCGCAAGCTGGCCCCCGAGGTGCACGTGCCGCACCAGCCCCGCGCGATCGAGGAGGAAGCTGACGCTCGTGTACTGGCGCTTCGGATGGCCGTCGATCCACCAGCGCTTGAGCGTGCGCCAGTCCGGGTCGATCGCGACCGGGAAGCTGTACCCGAAGTGCGACAGATAGCCTTTGACCGCCGCCGGATCGAGCGGCTCGTCGTCCTTGTGGTGATACATCCCGACGACGACAAGCCCTCGTGACCGATAGCGCTCGTCCAGCGCCTTGAGCGCCGGGGCGGTGGCGCTGCACAACGGGCAGCTCGGCGACATGAACCAGCGGACGAGCACGACCTTGCCGCGCAGGTCCGCCGGCGTGAGCGGTGGCGAGTTGTACCAGGGCCCCACGTCCCAGGCCGGCGGAGGCGCCCCGACGACGCCCGATACATCGTGGTCGAAGCCCGGATCGCCGCCCGACGTGGGCGGGGCGCTCTCCGGAGACGGCGCAGGCGCGGCGGGCTCCGCGGGCGCGGGCCCCGTGGGCGCGGACGCGGGCACGGGCTCCGGGGAGGCGCACGCGAGGGCGAGCCCGGCGAGCGGCAGCGAAAGCAAGCGCACGAGCATGGCGATACCCCCGCGCGCGACGATGGCAGCCCGGCGCGGGCGCGTCAATCCAGGCCGGACGGCGCCCGCCGCCTTCTCCCACCGTGGAATACGCTGCGAACGCCGCCGCCGGAGCCGGGTCCTCCCCGCTTCATGGCCATTGAGCTCCACCGTCGCGCGGGCGCATCCTGCCGAGCCATGCGAGCAGGGGAGCTTGTCGACGACCGATTCGCGCTCGAGGCGCAGGTCGGCGCTGGCGGGATGGGCACCGTGTGGCGGGCGCTGGACCGCGCGACGGGCGAGGCCGTGGCGCTGAAGTTCCTGCGCGATCCGGTGGGCGGCAACGCCGCGCGCTTCGCGCAGGAGGCGCGCATCCTCGCGGCGATCGAGCACCGTCATGTGGTGCGCTACCTGGGGCACGGCCTCGCGCCGACGAGGGAGCCCTACCTCGCGATGGAGTGGCTAGAGGGCGAGGACCTCGCCGCGCGCCTCTCGCGCGGAGGCCTCACGCTGGAGGACAGCTTGAGTCTCGTCGAGCGAGCCGCTTTCGCGCTCGGCGCGGCGCACGCGCGGGGGATCGTCCACCGCGACGTGAAGCCGAGCAATCTGTTCCTCGTGGGCGGCGAGGTGACGCGCGTGAAGCTGCTCGATTTCGGGATCGCGCGGCAACCGGGCGCGCTGGCGACCTTGACGCAGACAGGCGCGATCCTGGGGACGCCCGGATACCTGGCGCCGGAGCAGGCGCAGGGCGAGCGTGAGGTGGGGCCGCAGGCGGACGTCTTCGCGCTCGGCGCGGTGCTGTTCGAGTGTGTGACGGGGAGCGCTGCGTTCCGAGGAATGCAGGTGATGGCGCTCCTCGCCAAGCTTCTCCTGGAAGAGCCGCCGCGGCTCATCGAGGTCTGCGCAGACGTGCCGCGCGAGCTATCGGAGCTCTGCCATCGGATGCTCGCGAAGGATCCCGGGGCGCGGCCTGCCCACGGCGCCGCCGTGGCGGAGGCGCTCGCCCGGATCCCGAGGGGGGCTGCTTTGCGCGCGGCTCCTCGGCACGACGCGGCTCGCGCTCCGATCGGCACCACGGAGCGGCGGCTGGTCTCGATCCTGGCGATCGCTCCCCCGCAGGACGAGCCGGCGGGCCAGGACGACGCGACGGCGCCCGTGGCAGGGGCCTCGTGGAAGATCGTGCGGGACGCGGTGCAGCCGCTCGGGGCCACCGTCGACGTGCTCGCGGACGGGACGATGCTCGTCGTGCTGGCGGGCGCGGGCGACGCGACGGATCAGGCGGCGCGCGCGGCCCGTTGCGCGCTCCGTGTCCACGCGGGCCTGCCGCGCGCGGGGATGGCCCTCGTGACCGGGCGCGGGGATACGACGGAGCGGCAGCAGGTGGGCGAGATCGTCGAGCGAGCCGCGACGCTGCTCGGGCGCATGCGCGCGCACGGGAGCGCCAGCGGGCCGGTCATGGTCCTCGACGAGGTCACGCGGGCGCTCCTCGATACGCGCTTCGAGGTGACGGAGAGCGGAGAGCTCTCGGTGCTCGTTCGCGAGCGCATGCTGGGTGAGCATCCGCGGCTGCTGCTCGGCAGACCCAGCCCGTTCGTGGGTCGGGACCGGGAGATGCAGCGCCTGCTGGGCTTCCTGGAGGATGCGTTCGAGGATCGGAGGGCGGTCGCGGCCACGGTGACCGCGCCGGCGGGAATGGGCAAGTCGCGGCTGCGGCTGGAGCTCATGGGGCGGTTGAGCGACCGCGTACCGAATCTGGCCATCGTCATCGGGAGAGGCGATTCGCTGGGCGCCAAAGGCGGGCTCGGGCTGCTCGGCTCCGGGCTCCGAGGGGCGCTGGGCCTCGAGGCAGGCGAGCGGCCCTCCGCGCAGCAGGAGAAGATCCTCTCGGCGGTGAAGAGGTACGTTGCCGGCGACGCGGCCGAGCGCGTGGCGGAGTTCCTCGGAGAGCTCGTGGGAGCGCCGTTCCCGGACGAGAAGAGCCCGCGGCTCCGGGCGGCGCGCCACAACGCGCAGCTCATGGCCGAGCAGGTGGAGTCCGCGTGCCTGGAGTTCATGCGGGCGGTGACGCGGAGGGGGCCGCTGCTCTGGGTGCTGGAGGATCTGCACTGGGGTGATCCGGCCAGCGTGAAGCTCTGCGACGTGGCGCTGCGCGAGCTCGAGGACGAGCCGTTCGGTGTGCTCGCGTTCGCGCGGCCCGAGCTGCACGAGATCTTTCCCCGGCTGTGGGCGGAGCGGCACGCGCAGGAGGTCCGCCTGGGTCCGCTGTCGAAGCGGGCGGCGGACGCGATGGTATCGGCCGCGCTGCGCGATCCGGCCGCCGCTCGACAGGTCGCGGCGCTCGTGGAGCGGGCGGAGGGAAATGCGTTCTTCATCGAGGAGCTGATCCGGGCGGCGGTGGACGGACGCAGCGATACGCTGCCGGAGACGGTGCTGGGGATGGTGGAGGCAAGGCTGTCGGCGCTCCCGCTGGAAGCTCGGCGCCTCCTGCGCGCGGCGAGCGTCTTCGGGGATCGCTTCTGCAAGAGGGAAACAAATTCTACACGCAAAAATAATATTGAGCAGTTCCAAGCACTTAGAGGCTACGCCCGGCCCGGGCGGCGGTCAGCGGGCGGAGACGGGGGACGCTGTGTGCGGGCCATCGGGGGCGCCCGTGCGGTTCTGGTCGCGGATCATCGGGGGCGCGGTTTCGGAACGCGCTGCGCCTGGGGCAGGAGCTACGGCGGCGCCGAGCCCGACGTCGGGAGCTTCCACCGCGCGCCGCTGCGTCTCCAGAAGGCAGGGCCCCCGAGTCAAGTGCGCCGGACCCGTCCGTCGCTTGTTGCGAGCGCAGGCGTCCAGGCCGCGCGTGGACGCGGCACGGCAGGATTGTGAGCCGCGCGGCGCGGCCCGCCCTTGCCGCGCTGGCCCCGTCGATCGAACACGCGCGGGTGGTCAGCGACGCGATCGAGCTCTTGCTCCCTGTGCTCTTCCGCTCCGCTCGCCGGAGTACCGCACACGGTGATCGAAGTGGCGGCGCTCCTGCGCGATCTGCATCGCCTGCGCGAGGCGATCGGATTAGACGCGGCTCTGCAGCTCGACGACCCCGAGACGCCCGCCGGGGCAACCGCGGCCACGCCCGCGAGCAGCGGCGGGGGCTGCGGGCTCATCCGGGCTGCGGGGGCCTGCGGAACCCCACCGAGGCCGTCCGTTGCCGGTCTCGTAGCTGCCCGCCGACGGCGCCGCCACGTGCGGTGCTCGCGGGCGGCACGGACGCGCGAGCGACGTCGTGCGGCTCCAGCCGCGTGAGCGCTAGCGCGTCGTCGTCGCTGATCGCGCAGGCCACCGCCAGGCGCCGCGCTCGCGGGCGCGTGGCCGCGCGAGCGACGGCGTGCAGCTTGGCTGGCGCACGCTCTGGACGGTACGATCCCAGCCCAGTGTGGTGTTCTCGTCTAGATTCCGTTTGACGCCGATCCTGTGATCGGAAGAATGGCTCGTGTGTCCCTGGGAGCAAGAGGCCATGATGGCAATACGTCTTCGTTCGAAGATAGTCCGCCCCTGTCTCGTTCATATCCTTTCCGCTACGGCAATATCTCAAACTGGTTGCACCATCCTAGATGAAAAGCAAGCGCCGACATGCATGGACCCATCTCCTCAGTGTCAAGCGTTGTGTGGGCAAGAAGACGTGTTCCCTCAGACAGTTGGCTGTGGGAGAACGACGCCGCTTCAGAACCAATTCGTAAAAGCATTAACCACAAAGACATGCAATCAATGGCGCGAAGCACTACCCACCGATGGCAGCAGCTATCTGACCATTACTCCTCAAATGATCGGGATAACACCCGTCGCAAAGAATCCGTGCCTGTACTAATCCACGTCTCTCCTGGAGACAGTCCTGGATAGTTGCTTTTTCATAGCAAATAACAGCGAGACAAGGTGCAATCACCATCAACCCATCCAATCGTCATGGAACTCTTATCGAAGCCGACGAAGCGAATTGGATTCGGACTCATCGCCGTTGTCGCATTGGTAGGAGCATATACCTTGGGGCGAACTTCGGTAGAGGTTCCTGAAAAATTTCAAACTCACCAGGACACGGCCAGCACAAGTGGCACCGATCTTCAATCAATCATAAGTGCTACTCAGGAAAGGCTTATTAGCTGCGAAAACGCTCTCTATCGCCGCGAACAACCACTTCACAAAAAGGAAGAGCAGCCTCACATCAAACAAGACGAGCCTACCGCATCATCCCACTCGGAGGGCTCGACAGAATGTGGCACCATATCGCAAAAGAAAGAACTGCAAATGATGGCCAAAGACTGTAGAGAATTCAGGAAATCGTTTGATGCGTATAAGGCAATACTAGAGAACGACAAGATCGACTGCGAGACGATCTTAGCAATTCGAGATTTGGCCCAAAGCCAACATTCGACTTGCGTCGCGATCATAACAGCCAACGAAGACGCCTCGTATCAAAACCTAATGAGAGACCCTAACATCAGCGAGTTGGTAGAAGACGCGTACACTTTCAGAGATGATGAATATAGCGGACTTAGCGTCAATGGCCTAGTGAAAAACAAGAGGTGTCTAGTTGAGCAGTAATGAGATCACGCATCACTCGGGGAGAACTTGGTGCGTTGCCGGCGTTCATGTTAGATCAACTAGCTTTGCGCATTTTGTTGGGGCTTGGGGTCATTACTGTTAGTGAACTGGCATCGGCGCAAGAGAAAGAGTCTCAAGGAGCATTCTATTGGGACGGGTTCCATATTAATGGAATCTTTCAAGCAAAGCTTCCTCTTCTCTTGAGGTTAGGAGTTTCATACAGCGGAGGAACAGCTCCGGGGGCTGTCCATGTAGCCATGCTGAACTTTGGTCAGACCTTGAGTTTGGCGAAGGAGCTCAACGTTGGCTACCTTCTGGGTGTGGGATTAAGCAAGGAAAGGATGTCGACCGTAGAAGACAAGGTATTGGGGATACATGCCACGTTCGAAACCGGACCATTTCGGGCAAGCGCGGCCACGAACCTTCAATTCTATGCATTGGGCGAGGCTATTATTCCGATGTTCACTACGGTCTTGAGAGGACAAGGAGCGATTTTCCGGACCACGCATGTCGACGCTTTCGTTGGCGGAGATCTTTTTCTTCGCAATCTGAACGTCCAGTTCGGCGCCACAACCGGATTTCGATTCAGGGACGTCGTACTCTTTGACCGAAACATAAGCGGACTCTTGTCGGCGACGGTGATGAATACGTGGGCCAGTGTCCCTGCACATGGATTAAGCTGGGCGGCCTACGTGGAGCCCCGTCTTGGGGTTGTTGTCGATCTAGAGACCAAGGAAGAAGAAAAGCGTGATCAGATTTACGAGTATGGGCAATACTGATCTTGAGCGTTCGCGGAGCAGGGCGCGATGTCAATCTCGATGACCGATGCAGCGGACATCGGAGCAGCAACGAGAGCGCGGCCTTTGCTGTCTCCTCAAGCCGTGCGGTCGCTTCGATCGGCTCCTGTGCCGATTCGATTTGTACACGTGACGTCGTCCCACACTGGGACGGAGGCCTCTCGACCCAGCGAGCGTGCCGGGGCGCGCCGGGCTGGGCAAGGGTGCGCTCGCTGCGCGAATCACGCCCGCGCGGCCGCCCTTGCTCCGCCCGGCGCGCCCCGGCGGCTGAGCCCTCGCCAGACCACCGCCACGGTGTGCCTGGGGCCCGAGACCAGCACTGGTCGCGACCTTCCATTAAGCCATCACAAATGCCCGTTTACCGATCGCAGCACACGACGTGTATGTCCCCTGGCTCAAGTGTACCGCTTTCAATCTTGGAGACTGAAGGAATGCATGTGCCGGGCTCATTCTCCGTGAACGCGGACCGCATCGCCGCGAGTGGCGCGTTGTCAGCCCTGCTGCAAAGCGGAGAGTCGCTGCTGGAAATGACCGTGTTGCCAAGCTCGTCGAAGCAGCGAACGTCCTGGTAGAGCGTGGTCTGCACCGTGCACCTTCCGCCGGTCGGTGCGCCACAGGAGCAGGGCGAGCAGGTACGGGCGTCAATGACGGTGGAAAATTCATGCCGGAACGGGTAGCCCTTCCAGCATTCTCCGTTGTCCTGCGGAGGATAGCAAAGGCGGGCTGCGGCAGGGGCCCAGTTTGGAGTCTTGGGTTTACAAGCCCTTACGTCGGCCAGGCTGCGGCGCGATGGTTCCGATGCGGGTGCCACGGGGGCGCAAGGGGCCAGCACCGGCGGCTCAAAGGTCACCGACGCGAAGGCGTCGCTCTGGATGGGCGTGGCAGCCGGCGCGCAAGAGCCATCCCAGGATCCGCTGGCCTCCACGGCCCCTACGTCGTCCTCGCCGGGGCACACCGAGGCGTGTGCGGTTACCTTCGACGGCAGCATGCAAGCGGCTGGGCCGCACTGGCATGGCTCACATTCGTCGGGCGCATCCGTCCCGACCAATCCCTCCCACAACACCTCGTCTCCGAAAAGGCAGTCAGTATCGCCGCCATGGTTCGCAAAGCGAACGTAGATTTGGTCGCGATCGTCTGGAGGCGGCAAATCATAAGATTCCGACGAGCAGCCGATGGGGGCCAAAGCGACCAACGTGAACAACACAGCCGAGCGCATCGTGATCACCAACCCTTCACTGCAACGGTTTCCTGGTGCAGCAGAACACGCGCGTCTCGCCGCGCTCTACGAGACCCTGAACTAGCGAGAGGTTCGTTGTTGGCGTGCAGGTGCCCGGTTGGTTCTGCGTGAGGATCGCGCGAACCGCAGCAAGGGGCAGCGGCGCTGGAGTGTCGTGACATGTTGTGTCGTTAAGTGCAATCCCGAACCCCGTGTCGAGCTGATTCTCACACGTGGCATCGCCGTACAAGAGCACGTCGACTCTGCAATTGCCTCCTGAAGGGGGGCTGCACGCGCACGGCGTACACGTGCGATTGTCGCGGATCCTAGGCGTGTATTCCAATCTCGTAGAGAATCCCGGTCGGCACAGTCCGTCAGCCTCGGGTGTGATGCACACTAGAAATTCATCCGGAGCAATCTGTTCCGCTTCGTAGGGACAGACCCTAGAACGCCGAACGGTTTGAAAATTATCTAATTTCAATCAGTTACGCAGCCTCCGGGATCAGCCGCTGGGCCGCCTCAAGATTCTGGATCGCTGCGGCGCGCCGGAGGTCGAACAGGTTTCTCCTGGCGCCGATGTAGCGTGCGCTGTGTCCTTTGCGTGCCGCGATGTGGGCAAGCGCATGCTCCACAGCTGTCCGCTGCCGGAGCACGGCGCGTCCTGGCCCGGTCTGCTGCAACTTCCGGAACTTGCCCTGCAGAGCTTCGTCCTCGGCGATGGACACAGTCCGCCCTCGCCCCGAGGCAGCTTGCGTGCACTTGGCTCGAAGCGGGCACGCGCCGCACTCCTCGGGATCGAACTCGACCGTGTCGCCCGGCTCGAACACCTCGACCTGTCCCGCTGGACACGTGATCGTCTTGGCGCGCAGGTCGATCTTGAAATCGCGCTTGCTGAACAAATCGGGGCTTCGAGCCCGCTGGCCCCAAGGCTTCGAGAACACCTGGCCACCCGCGCGGATCACGTCGTCAACGACGGGACTGTTTACGTAGGCGCGATCAATGTGGAGCTCGACGAGGCGCAGCCGCTGACGCTGGACGTCCTCGGCGATCGGTGCGGCACCCTCTTCTTCGGGCCGATTTGCAGGCGTGACCGCGCAGGCGACAATGACGGGAAGGTCAAGATCGCGTGCGATGTGCTCCTTGTAGCCGTCGAACCGCTTCGAGCGGCTCTTGCGGCCGTGGCGCATCTCGGCGTCTTCGATGGAGACACGGCGGTCAGGTGCAACGCCCTGCCGGATGCGAACCGTCCCGTCCTCGGCTGTCTCCAGGTCCTGGTCTCGAACCTGGGTGACCGCATCCAGATAGGTGCGAAGCGGCTGCTCGACGACGTCGTCAAGATGGCGGTCGACCCACTGCTGCAACGACGAGACCTGCCGCTCCAGGATCTGAATCGCCGCCGCCTTCTGCTTCGGGTCGCTCCAGTCGAGGTCGAGCCCGGCCTTGATGCTGGGCGCCAGAAGCAGCGGGATGCCCGCCTTGCGGCAGATCTCCTCGGGCGGACGCTCCGTGATCTTTGACACGACGCGGACGATGCTGCGTGCAGCATGGCCGAGCAGGTTGATCGTGTCCTCAACCCGCCCGGCCCCCGCTAAAGGGCGGCTATCGATGGCCACCCGCAGCGCTTTCGACACCGCACGCCTTTCGCCCTCCGTCATCGCGCCGGACCGAACCAGCGCCACGGTCCGCTCCAGCAGCACCCGGTCCATCTCGTGCGCGACCATCCGCTCTCGGAACGCCTGCAGCGCGCCCTGCGAGAACGGAGGTGTGTCCGCACCCAGGCAGCCGAGCACCATCTGCCAGCGCAGGTCAACGACGGCCAGTTCCACCGCCTCGGCATCCGATGCGCCGACGTAGCCTTGGAGCAGCGTGACCATGCACATCAGCGCCGGCGGATGCGGCGGCTCACCTGCCCCCGTCGTCCGGTACATGCCCTCCAGCTGTTCCTGGAACGTCTCGTCGAACAGCTCGTGCCGGTGCAGCCTGAGAAAGCCGAACAGTGCTCTCACGCGTGTCAGCCGCTTCATCAGCGCCTGCTCCTGCCGCGACAGCTCCACCGGCGGCGACCATCGTTCCATCCGTGAACCTCCGGACGCGGACGAGATCATGACCCGGGCGAGACGGTCGAGCCTTCCATCGAAACGCCCGAGATTATCACAAAATCAACCTGATCGGTCCTCTAGCAAAGTCTCCTGAGATGTGCGGTGGCGCTAGTTGCGAAGGAACACACGCCCGCTCCAGGGCCGGCGGCTCGTAGGTGACCGAAGCGAAGTCATCGCGCGCGACAGGCGAATCAACTGGAGTGCATACGCCGATCAGGCTCGCTCCAGCGTTGAACGTCACCGGAGTTCCGGCACCGGGATTGGAGCAGAGTGACACATGGGCCGTTACCGTGGACGGCAAGACGCAGGCGGCGAGGCCGCATGTACAAGCGCCGCACGCCTCTGGAGCCCTCTCATCAGCCCAACCCTCCCATTCGACCAGGCGATCGCCGGGACAGGGAGGCGCCTTCGCTTCGGTACCCACCCAGAGCCACACAGGATCATCGTCTATCCGTGGGCCGTAGATGTCCAGTTCATCCCCACAGCCAAGCAGCACCGCCAAGCTGAGAGCAAGACAAGAGCCTGATCGCACGGTGAATCCTCCCCTTGACTCAGTACTTGTGCTGCCCGCAAGCAACCAGCCCGTAGCAGATGTCGTCGTCCTTTGACGGCGTCCTCACGGCTTGCTGCGTGAAAACGGCCCGGCGACCCGTGACGGCGCGAGGCTCGACAGGCGGTGGTGCTTGGCGCGCATCGGACGGCTGCGGGGGAGGTTCTGTGCTGGCTCGGAGCGCTGCTACCTGGACATGCTGGACGAGCCGCGCCAGGCGCGGCGCGGCTCTGCGGGGGGACTGCCACCACAAGAGGAGGAGCGCTCCCGCGCTCCCGAGCACGATAGCGAGGGTGAACACGGCGCCGAGGAGGCGCACCGGGGAGCTGCGCCGTGTGCTGCCGCTCGAGCGCGGAGAGATCGAGAGCGCCGGTGGGACGGGCAGCACCGGGGAACGCGGAGGAGTCGAGGGGGGCGGCAGTACGGGCAGCATCGGATCGAGGTCCGGTAGCTCGGCCGAACGCAACCGCGACACGACCGGAGGCGCGTGGGAGACGGTGTCCCGCGCGTTCCGCGGCGGCATCGCGCTCTTGAGCGTGTCGGGCGCTCCGGAAGGCCGCGGCGTGGCGACCGGAGGCGCATGGGCGATGTCATCCCGCGGTGGCACCACGCTCTTGACCGCATCGGGCGCATCGGAAGCGCGCGGCGTGGGGAACTCGCTGGCTCGTCTCCCCTGTTCACCCGAGACCGACCGCTCCGCCTCGTCCTCGACAGAGATCGGCGCTTCCTCGTGCGGCGCGCGCCGAGAGCCGGATGGTTCCGCGAAGATGTGCGCGTGGGGAAGCTCCGGCGGTCCGCCAAGCCCCTCCCACTCGCGGGCAAAGGGAGTCAGAACAGAGAGCATCTTCTCGATGCTCGGCTGTCGTCGCTTGGGGTCTTCGTAAAGGGCGGTTTTTATCATCACCTGAAGCACGGGAGGAATTCCCGCGGGGAAACTCCGGTGAGGGGCCCACGGCGAGAGCGCGCGTTTGCACAGGAGCTCGTACATGAGGGTGCCGAAGCCGTAGACGTCCGCGCGAGGTCCCAGCCGACCACCCGAGATGAGCTCCGGCGGTGCATACCCGTACGGATCTTGGCGAGCTTCCTCCGCACCGAGCTGAAAGAGACGCGCGAACCCGAAGTGCGTTATCGCGTAGCGGCCATCGCCGACGATGAAGACCCGATCGGGACTGAGGGCGCCATGGATGATGGAAAGCGCATGCGCACGCATGAGACAGCGGCCGATGTCGATCAGCACCTTGAGATCCGCCGGCCCGAGGTCGTTCTCGCGCGTCGCGTCGACCAGCGGGATCGCATCGCTGAGCACGGGGGTCGCTGCCCACGCAACGGAGCCGCTCACCCCGCCGTAGAGCACGCGGACGATCTCCGGGACCTCGTCCGAGAGGTGCTGAAGGCGCGCGATGTCTTCAGCGAACACGGTCTCATCGAGGGGCGTACCGTCGCGGACGTGCAACCAGACGAGATCCCTCTTGTCGCCGATCTGCCGCGCGAGGAAGTGACGGACCATGCCGCGCTCCTCGTTCAGGATCTCGTGGCCTTCCCAGACATGGCCGATGGCTACCATACGAGCTTGACCTCCGCGCCTCCGGCTCGCGTCCGGATCTCGGCCTTGCCCCGGGGAAAGACCACATAGACGACGGTCGCGACGCCGAGCGCTGCGCCTGTGATGAGGGCAGCTGTGCCCAAGCCTTGGAACACGTTGGCTCGTGTGTTGGCAGCGTTCGCTTCATCGTAGACCTTGCTGAACCGTGCACTGCTCGGGAGCATCGAGCCGTCATACAAGCGAGACACCTTGGCGGCCGTTTCACGCTCGGCGGCGTCGCTGGCCAGGCGAAGACCGACGCCTGCACCGAGCAGCGCGACCGAGCCGGCCGCGCCGGTGCCGATGATCCAGGGGTTGCGCCGGGAGCGCCCCGACGCTGGAGCGACCCGAGCCGGCGCACGGGATTTCGCAGAGGAGGACTTCGGAACCTCGAAGGAGAGGGAGACGTGCCGCGAGTCCCCCGCCGCCACCTTGACGAGCGCATGGGCCACCTGCCCCTGCTTTCCCGTCGCCGTGACCTCGTGCTGTCCAGGGGCGACGAAGACACGACGGCCCCCGCTCACCTCGCGACCGTCCACGAGGATCCGCGCCGTGTCCGGCGGCGCGCTCACCTGGAGCTCGGCCACGCGCTGCCGGACCGCCGCGAGATCGGCGTGTCGCACCTCGTAGCGGCGGCGCTCGAGGTCGTTCGTCGGCGCGGGCATCTGCTCGACGCACTTGGAGAGCTCCTCCGCAGCCTGCTCGAGGCGGTCGAGGCGCAGATCGTATTGCCCGAGCTGGCAGATGGCCATCGGCGTGGGATCGAGCGCGTAGATCTGCGCCCAGTACTCGCGAGCGCGAGCGATCTCAAGCCGCTTCGCGGCCTTCTCCGCCTCTTGCATCAGCTCTTGAACTTGTCGGGCCGGCGCTGATGGCTCAGCGGCGCCAACGGAAGGCAGCAAGAGGATCGCGGCGAAGGTCGCGGCGCGTGATGGGCGCTTAAGGAGGGCAGCACGACGCACGGTTCACCTCGTTGGGAGCTGATGCACGCTTCCGTGGTTTGGCTCGCCAGACTGGATGGGATCCGATCCGGCGCGGCGTCGCTATCTACATCATCCAGTTGCCGGCGGGGAGCGTTCCAGGCGTCGCTGTCTCCCCGAGCGATCCGGGGCAGGTGCATTGCGTGTTCGGGTGTGAAATTCCCGGTAGGTGTCAAAAAAAATGCATGTGGTGAGCGCGACAGAGGCCCAGCACCCGGGCAGGGCGTGCGTTCAGGGGGGAACCACAGCGCCGCGCCGCTGTCGACGCGACGGCGGCTGGTTGCCGCCCACGGGGGCGCCGAGGAGGACGCGATGCGCGAGCGGGGCGCGACGGACCGGCACCGTGTGGGTCTTACGCACACAACAATGGGTCCGCAATGGATTCCGTTCGCACAGTTGCGGCCGAGCGGACGCGAGGGAGCTCGGCGAGCCTGCGACGTCGGCCGGCGCCGCGATGGGCTCGCGCTCGATCAACGTGTGGAGGGCCTCATCGTCGAGCCCCCGTTCAGCGTGGCCGTGCGCCGCGGGCAGCGTGGGCGGCATCACGGCGGCGCGCCCACCGCCCTGAAACGGGCCCGTTGGTGTGGTGACATCCGCGGGCTGCGCACCTGGAACTGCATGACGCCGCCGTGGGTCACCGTTGCGCGCGGTGGCGGCGCGTCGGGGCTCCTCGAGCGCGCCCTGGCCGATGGGCGCGACCGTTCCGTGCGCGGGCGGTTCGTCGGAGCGCGTTCTGCGGCAGATCGCGATCACCGCGGGCTGACGGCCGAGCGCCCAGAGCTGCGCACCATGCCGCCCGTGCAGCAGCGCCGCCCGCCAGCGCGGCCCCACGACCGCGCGTCTCGAGCCGCCGACGGCGCAACGGTGGCTGCTCCTGCCATATAGAACCTCCAATGTCGTGGTGTTTCGAGTTCGGAACGGAGCCTGAACGAGAGCCCGTGAGGAGGCCCGAAATGGTAATTCTGAAGATCCGGTAACTCGTCGCGAGTTACCGGGATCTGGTCAGCCGGGGAAGCCGCTCTGGTGACGCGCAGTTAGGCCGTTTCGAGAGAGCGCCAGAGGGCCCGGTTTTGGGGGGTCGCGAAGGGGTCGATTTGGTAATTCTGCGCGGGGTCGGCTGAGGATCTCCGGCGAGCCGCCTCGGCTTTGTCGCATACGTATGCGACAGGGCGGCGCGCGGCAGACACGGCCGCCGCGGGGCGGGCCGAGCGGCGCGGCGCGAGCTGGTCCCGGCGGACGCCGGGGCGGCCTGGGCCCAGAGCTGAGCACGTATCGGGGCGCGTGTTCGGCGCACGGGGCCGCTGCGCCCGTCCAGGCGGGAGGCTGACGCAAGGCGGAGCTCGCCCAGGTGGACGCCAGCGCGGCCCGCGGCCGCGCCGCCGGGCGAGCTGGCCCCGCTCGACGGCCCGGCCGTGGGATCGCCGGAGGGGCCACGCCGCACACCGAGGTCACGTGATCGGGTTCCAGCGAACGCCAGTCAGGTCACGGTGTCACGTGAGACCCGGCGTCCTGTTGGTCGCGCGCTACATCACAATTTAATGCCGTCGCCCTCGCCTGGTGCCGACTCTTGTACTCTGCTTTAACGCTCTTTAAGGTTGAACGAAAAATGAAGGCTTCGTTGTGGCGGGTCTGTGGCTCCGTGCTTTTGTAGGCGCATGAGCTCGCGGCGCTGGTACGAGCTCGCGTGCGGAGTTGTCCGCGCGCCGAGCCACGTCCTCGAAGAGTGTTTTCAGATGAACAAGCAGACCCGGTGCCACCTGCGCGCGATTGCACGGCTGCACCCCGACATCGGCAACCTGTGCGATCAGCTTGAGGCGCCCTGGAACGCTGTGCGAAGGATCGCGCACGCGCCGGGGGCGGCGGCGCAGTGGGAGCGCGCGGCGCAGGTGCTCGGTGAGCTCGTGGAGAAGCGCCGGGCAACGGCGCCGCGTCGGTCGAGGCTGGAGGCGGCGCGCCTGGAGGCGCTGAAGCGAATGGGACCACCGATGGAGGGGCCAGGAGAGGTTGCAAGCAGCCTGCGAGCCGCGTGGGAGGCGGCGGAGCGCGGGACGACCGCGGTTCCAAGCGCACGTCCGGGCGATCGGCGTGCTCGTCTGCGGTGCAGCGCTGCCCGGCGGGAAGCGCGCCAGTAGAGCACATGAAGCGGCCTCGCGATGCACTTCCGCCCCGTCGCGCTCCCGCGCGTGCCTATCGCGCCCGCTCGCCGATCCTATTCAGGGAAACGGAGCGGCTCGACCTGGCCCCCGTCCTGCCCCGTTACCATCTCGCCCGAACAATCCCACGAGTGCCGCCTTTGCCCGGCGGTCCCACCTCGTACGTGAGTACCCGTTCGGCGACCAGCATGCTGTCCTGGAGCTCCTGCGCTGCGTAGAGATCCGCGCCGGAGGTGTGGATGGACGAGAGCGCACGCATCTGGCGCGACCGGGTGGCGCGCTGGCACAAGAGCGGGCAATCCGCCCGGGTGTTCGCGGAGCAGGAGGGGGTCAACGCCGGGACGCTGTACTCCTGGGGCCGCCGACTGGGGATGAAGCGGAGCGCGTACCGGCAGAGCGCGGAGAAGGCGACGCTGCCCACGTTGCTGTACGTGACGCCTTCCAGCATAAGCTGGTCCTCGTCGAGGTACGCGACTTCGATCGCGTCACCGCCACGCCCGGGGCCGCATAGCCGCCGTCCTCCCTTGGCGCGGTTCGCGTCAGGCTCGCCGCGGACCCATGCACACCTCGCCGGGAACGCTGGAGCACCGCCGCCGTCGTGCGCCTCCTGGCATGCGACTGTCAGCGCACCGTGATCGCCGGCGGCCTGCCCCACGGACCGCGACAGGCCGCGCTCGGGAGGACGGTGGCGCACGACCCTGCTTGCGCACGGCCGTCAGCGTGCGGGCATCGTCGGGTCTGTCCCGTGATGCCGCGACGGGCTGCGCTCGGGCGGGACGGTCGCGCACGGGTCCGCTCGCGCAGCACCTCGCGCGCGGCCGTCAGCGCGCGGTCATCGGCGGCCGCTTGCCCCACGGCGCCGCGTCGGGCCGTGCTCTCTCAGGACGGCGGAGCTGTCGTGGACCGCCCCATCGGATCGCGCCCGAACCGGCCAAGCGGATCGTGGGCAAGCCCGCTCGGACCCCGCGAGGCAGGGGGCGCGGTGCCCGCTCACGTCAAGGCGCCGCTCCGCGGAAATTCTAACAAATTTGAGCCATTGACGTGAGCTGCGCGTCGCGCCGTGGAGGGGCAGGTACGGGGTTGGACCGGGGAATCTTGACCGATGCAGTCGTGCTCCGTTCTGCCGATCGGGTCGCGCTCCATGAGCCGGTCTTCGACAGATCGCATCGGCATGGCTGCTCGGAGCACGTCGAAGTACGAATCGACGATGCGCGATGGCGTCCGTCAGGTCGTTACTAAGGCTGAGGTTCTCCAGAATCGCGATCCAGGCGTCACCGACCCGGCCGAAGGGACACCGGGCCGGCCGCTGAGGTCGCCACCTCCGGCAACATCGCCGCCATCAGCAACTCGACGCAAAAATATCGCGATCGGGTCGCCTGGTCGCCCGTACAGAAGGCTTGACATGTCGGGTTGGCTATCGGCTACGCTACCTCCCCACGATGAGCAAGGAGGGGGCATGCGGGGTGAGAGCTGGTGCATCGGCGGTCCAGGCGGGAGCAGCAGCCCCTGCACCCGAAGGCCGATGACGTCGAGCTGGACGCGAACGAGCAAGGCCGTGACCGAATCCTCCAGCGCGCGCGCCCGCTGTGCTGACAGGTCGCGGACGCCGCGGCCTATCTCCGGGAACACGGAAACCTATCGCTTCCAAAGTCGTTCCCACGGCGACAGACTTGCACCAGTTTCCGAAGAGGGGGAAGTTCCTCAGGAGCAGCGCCGACCGCTCTCCGGCCTTTCGGCCCCCCGGAAGACGGTCGGGAGCCGGCAAGAGCACCGTCTGAATAACCACATTCGTTCCAACAATGTCAACGGCAGGAGGCAGCGATGATTGAGCGATTGGGCGACTTGGGCGACCTCTTTCGGCAGTTCCGCGAGATGAAGAAGCTGACGCAGGAGGGCCTTGCAGAACGCTGCGGGGCGACTGTAAACCGCACGCAGATCGCGCTGCTGGAACAGGGACGACGTCTGCCCAAGCCCGAAAGTCTTCGAGCGATTGCCGAACAACTTGGGATCCCCGGGGAAACATGGGCACCGTTCGCGAGGGATGAGTCCCATCTTCGTCAGCAGTTCGAGGCATCCGTCGGGGAGTTGGTGGGTCGGGTGGTTGGGCTCCGGTCAATGGATATCGAGTCAGTTCACGCCGCCGAGGCGACTACTAAAACGCTATTCTCGGGAATGCTCACCGCAACACAGTCTTTTGACACGCTTAACAGCATACTTCTATTTTACGCTGTCCCCCGCATGAGTCGAGCTTTCTTCGATCGGTACCTTGGGGGCACCGCCTTTCAGTCGATTGAACTCTTCGACGCTGCTATTCGGCGGTTTCACGAAGAGGCCATTCGCCTTTTTAGCACTTTTGCCGAAGCTTATCGCAAGATGAACGCTTCGAATAATCTATCGACGATCTTGGAGCCTCTCGCAGCGAGAGACCTCAGCGCCTACACAGATCGTACGGTGTGGGACGCTCCAGATCCTGCAAGCCTTGAGGGTAACAGGATCCTTCCGATTCCGGAGCACAAGCTTGAGTTCCTGGGCTACATCTCGGCCGCAAAATACAAGGCACAAAAGAGAAAACGCGAAACGCTCGCCAAGTACCTTCGTGAGCTTGCGAAAGAGGTGCGGGCAAAAGGTCCTCATGCCTTGGATGAATTCGGCGAAAAGCGGCGCCGTAAGATCGACTCATTGATGCGTGAGTTGGGGTCTACGATGGCGCACACTCCCATCTCGCCCCTCTTTGTGTCTAACGCCGCGAATCTTGAGAACGAAGCAAATAGAATTCTCCGCGACGAAAAGGATGAAGCGGAGATGGAGCGCATCCAGGCACAGGCACTGTCGAATTTGTCCCATTACATCAGCGCCGATCACATGGACGTCTATGTGGCGACCTCCATGCGAAGCACGTCAGACTTCGTCTCCGTCAACCGTTTTGTAGCTCGCTTGTTCCGCCACGACCAGATCGCCCCGCTGCGCCTTCGCTATTTCAATCCAACACAGTCATGGATTGAGGATCGCGTGGCCAAAGGCTTGGTCGAAGCGTTGATGCTCAGACGCGCGAGTGTTACTCTTTACATGGCGCAGAAGGCTGACTCATTCGGCAAGGATTCGGAGGCGTCGGTGGCACTGGGCCAGGGCAAGCCCGTCATCGTTTATGTTCCGAAGCTTGTCTTGCCGTCTGCCGGTTTGGACTCTGAGTCGTTGATGGCGGAGACCGACCTTCGACTGCGTGAGATGTTGCTCGCACAAGGGCGCACTGCAGAAGATCTTGATGACCTCGACCACGACGGTCTGTTCACCGAGGCGCTAACGGCGAGAATCATAGCTCTGTCGGATAAGCAGATTACCGAAATCGTGCACCTGCATTGGGCTGACTTTGCTCTGCTAGACGAGTCCGAGCGGATTCGTGGAAAAGATGTCAAAGAGAAGGAGGCTAAAGACCAGGATACCGATCAAAAGAAAGACGAAGACCAGATGAGACGCGCCACGCGGCTTCGCGAAGAATACACAAAGTTCGTTAGTGCGATCACTCGTGGTGAGCTTCCGGAGCTCACATCGGAATTGCGCGTTGAGGTCGAGCGCATACTGGTTGCGACGACTGTAGGGTTTGAGATTAGACGAGCAAGGCTCTTCAAGGAGGTCCATCCGCTCGCGCTTCAGATCATTCTTAGCACGGGTGTTCTAAACGGAATTCTGGTAAGCAGATCGGTTGACTCGTGCGCATATCTTTTGCGTGGATTGCTCGAGAATAAGCTTCAGCTTGAACTCGAGCCTGATGATACCAATTACCGATTGCTTGAGAAGACGACCAGATCAACGGTCAGGGTCATCGCTCGGAACACGCTCCTCAACAATGCGTTGGACGGGCTATATGATCGCCTGTGACCGAACCGCGGTTCCTTGATTGAGCACATCATAACGACCTGCGATGACTAGTACACGTCCAACTGCTGCCGGGCGCGCTTCGTGCAAGGGCAGAGCCGCGAGCCGTTGAACACACTGAAGCTATGAATCGGAGCTGTCTAACGGAATAAATCCATGCATGCGTACAGGCTGCCTGTGTGAGTTGGCGTTCAGGGAGATAAGAAACAGGTGCGTTCATGTCAATGAAACAGCTTCCGCTTCCGACCGACCTGCAACATCAGCCGCTCCGAGCCGTCCCCTACGTCGCGCACGATGGCAAGCGGGCGGGCAACACCGACGCCCAGCACCTTTCGGTGGGACGTGCACAGTGGGAAGTAGAAGATCTCTCGGTTAAGGTCTTCCGACACGTCGACTCGGGTTGGAGCCGACAAAGCGAGGAATTGCCTGTTAGCCGTGCAATCGACCTCGTTATATTCGCCGCGTTGGCCCTATTTTGTGATAGCGATGAGTTGCCGGATGGTACATTCGAGAACCAACCGCACCCCCTCAAGATGCAACCTTCGCCACCTCAACCATGTGAAAGTATTGAGGAGGAGTACGCAGAGGATGTCGGTCGGGCTCGAGGGCGGCTCCGCAAGCTGCGAGAGGTTCTCAATGAACTGCATCGGGACGGAAGGATCTGACAGCGATGATGTCCCTCTCACTTCGAGTCTGGCGCTGAACGGCGCACGCCCGGGGGTGTTAACGCTCACGATGGTTGCTGCTCGGTTGCGCAAGCTGGTTGCTGGCCATCGCGAGGGTGACCGGTCCGATACACCGGTCGACGAACGGCCAGTCGCCAGCGCCCGACGTGGCCTCGACCTGCGCGGGCGCTCGGCGCCGGCCAGGGCCTCGACGGCCCCCGAGCTCCCCGGCGTCCTCGCCGACGCCGCGGCCGCTCCGCGCTCGATCAGGCCGCGGCACCGACCCGCGGAAGCCGCGGAAGGGGGCTCGCGGGCTCGCCGCCCGCCTGCCGCACGACATCCCAGGAAGAAGATTTTTACTGACGCTCTACAGTGCGAGATCGTCGGCATCCTCGCGCAGGTAGGCGTCTGCCTCGCCCCGCTCGGGATGAGGCTCGACGCTGATCACGCAGCGCTCGCGATCCGCCAAGACGACCGAGCCCACGGCCGGGGCTTCGACGAGGTGGACGCGCTACGTCAGGGCGTGACAGCCCTTCTCCAGGATGAGCCGCACGCGCATGCAGCGACGCTACCACCGGCACCGCCCCGGCGACGACGAGGGCAACGTGACCGGACGGACTGGGCGCGGATGACAGCCCTAACGCCCATCGCGATCCCCGGCCTCTGGCTCGCGCCTGCGCGTCCGGGGAACGCGCCGAGGAGGTGGGCTCGCGCGTCGCGAGTCGGGGCGGGCTTGAGGCACGCGGACGCACGAGGGATCGCCGACCCGGACCCGCGTCGCCCTCCCCGCTTGCCCCGCCCGGGCCCTTACTGTACACCTGTACACGTCATGAGCGACGGCAGCGCCATCGAGTGGACGGACGCCACCTGGAACCCCCTCCGCGGCTGCACGAAGGTGAGCCCCGGCTGCAAGCACTGTTACGCGGAGACCTTCGCGGAACGCTTCCGAGGCGTGCCTGGCCATCCGTACGAGCAGGGCTTCGACCTCCTGCTGGTGCCAGACAAGCTCTTCGAACCGTTCCGATGGAGCCGCTCGCGGAGGGTCTTCGTCAACTCCATGAGCGACCTCTTCCAGGACAAAGTCCCAGAGGAGTACGTCCGCCAGGTCTTCGAGGTCATGGCCTCCGCCGATTGGCACATCTACCAGATGCTCACCAAGCGTGCGGCGCGCCTCTTAACGCTCACCTCGCGGATGCCGCCTGAGATCGTTCACCGCAGGCATATCTGGCTCGGGGTGAGCGTGGAGGACCGAGCTTACGGGCTCCCGAGGATCGACGAGCTCCGCCGGACTCCGGCCAAGGTGCGCTTCCTCTCCATCGAGCCACTGCTTGAAGACCTCGGCCGGATCGATCTCCAGGGTATCGACTGGGTGATCGTGGGCGGTGAGAGCGGCCCGAGGGCCCGTCCGATGGAGGAGCGCTGGGTGCTCTCGATCCGCGACCAGTGCAGGGAGGCAGGGATCCCGTTCTTCTTCAAGCAGTGGGGAGGGGTCCAGAAGTCTCGCGCCGGAAGACACCTAGGAAAGCGAACGTACGACGAGTACCCGACCATCGAACCGGCCGCGCCGCCGCCCGCGGCCGTACGCGCCCAGCGGCTGGCGGTGATAAGGGACCAGTTCCTGCGGGGGGGGATGGCGGCGGAGTAGGAGCGCACCATGGCGAAGTACGATTGGTCCGACGGACCAGCGACGCTGGGCCCCCACAGCTTGGCAAAGCACGCGATCTTGAGGGAGTATATAGAGCGGTACATCCCGATCTTGACGCGCGGCGGCACCGTCCCACTAAAATTGATGCTCATCGACGGGTTCGCCGGAGGGGGCGAGTACGTCGTCGAGGGCCACGGTAGTACGCTCCATCCCGGGTCGCCGCTCATCCTGATCAACGCCGTCCGGGCCGCGGAGGCGCGGATGAACGCCGTTGCTGGCCGGAAAAAGCCGTTCTCCGTCGAGGCGAGCTACGTCTTCATCGAGAAGAACCCCACGACCTACGCGTACCTGGATGCGACGTTGAAGCGGCACGTCGGCGAGAGCTTCGTCCGGGACAAAGTCGACCTGCGGCGTGGGGCTTTCGAGGAGGAACTCGGTGGCATCCTGGATCAAATTAAGGGCACCAGCCCCAGGCGCCCGCGTCCGATCTTCGTGCTCGACCAGTACGGCTATCGTGCCATCCCCGTCGACTTGATCAGGCGAATCATGACGGAAATCCCCACGGCGGAGGTGTTTTTAACACTCGCGGTGGACCACATCTCGGCGCATGCACGGACGGCCGGAGAGGCGCTCGGCAGGCTGAAGGACGCGCGCCTGGTCGAGCCCGAGTTGGAGGCGTTCCTCTCCGGTCGCCGGGACATGGACGAAGCAGCGACGCTGTCCAGCGAGGACCGCGGCCGGCTGATGCGCTTGATCCAGTTCATCCTGCATGAGACGTTCGCGAAGCGCGCGCACGCCGAGTGCTACACCCCCTTCTTCATCACCTCGAAGCGCAGCCACCGATCGTACTGGTTCCTGCACCTTGCCAACAGTTCCAAAGCCAACGACGTTGTAAAGGCCCTGCACTGGTCGGTGAGCAACCACTTCGAGCACTTCGGCCGCGAAGGCACGATGATGCTCGGCTTCGACCCGGCCAAGAACAAATACCAGGCCGTCTTGCCGTTCCCGTTCGAGTTCGACGACTCGGCGAAGGCTCGAACAGTTAGGGCGCTCGTCGAGGAACTGCCGGTTATCTTCCAGGCCAGGCACCACGATGGCGTCTCTCTCAAAGCTCTCTATAAGGCCCTATGTAACGAGACCCCGGCGGATCTCGAGACGCTCGGCGACGCCGTCAATCGGCTGTGCGCGGACCTTGAGTTTGAGAAGCGCGGAGCGAATGGTGAGGAGCGCGAGGTGTCGACGAAGGTGAAGGATTCGGACATCATCCGCCCTGCCAGACAGGGCCGTCTGTTCCGCAAGTGAGTTGGACGAGGAGTAAAGGAAACGCTGTAGCTATCGCCCAAATGGCGTACACGCCGGCAGGCGTCGGACGTCGGACGAACCTTGTCTACCGGGCATCGGCGTCGGAGTCCATTCGCCTTCGACGCAGTGAGCGCAGGTGACCACCCGGCCTCCATGCAGAACCGGATCAGCAACACGCCGGGCTAGATTTACCGACCCCGGACCGGAGCGGGGGCACTTTCCGACGAACCGAGGTAGTCACGCGCGGACATCGATGGAGCAGGGAGCGCTGCGACATTCGTGGACAAAGACGTGACGGTCGAAGGGACCGGGAGCGCAACGGCGATCGGCGCAGGGCGGAGCGCTGGCAGCTCCTGTGCACCATGCGCCGCTGATATCTGCGATGGATCGCGCCATGTGATCCTGATCTGCTTGTCCTTTGTCGCCTCGACTTTCGAGGAGAACGCGCGGATCAGCGCTCGCTGGACGTCTACCTGCAAGATGCTCCACTCATCGGCTATCTGCTGGACATAGGCGTGCGCGTGCTTTCGAGTCTCGATGGTGTCGTTGCCCACCGTTTCTTTGAACTCGGCTTCCTTCGCCTCGATTGCTGCAAGCGAGTCATCGAGGCGATTCAGTTCTACCTTCACGTCCTCGACCGTGAAGAGCCTCTTTGCAACAAATTCCACCACGCGCTGTCGCGCGATCTTGATCTCCCGCCGCTGGGCGGCGAAATCTGGCTTCTCGATCTGGCGCGGCGGCCTGGTAAGCGAGGTGAGTAGCGAGCTAGTAAACGCCATGAATTGCTCTCCCGCAGCGGCGTCCGCGTCCGGCTGACGGAGCCATGCGGAAGACTTGCACCGCACGCCCTTCTCTTTCTGCTCCACATGGCCGCGGCAGACGTAGTAGCCTACCTTGTGTCGGCTGCTGCGGGGGACCGGAATCGCAGCAACGCTGCCGCCGCATTCCGCGCAGCGGCAGATGCCTCGCAGCAAGTGGTTGGCCGTCGCAGACTCGGCTTGTGGCTTCCTCCCCCGGCGTCGATCTCTCAGCGCGAGCTGGACGTTGTTGAACGTCTCATCGTCGACGATCGCCTCATGCGCGGGCACCCATTCGGCCGGAAGCTGCACGGCGCCGCGTGTCGCCTTCGGCCGCACGGCGGTCTTTGCAATGCGGCCCGTGTAGACGCGGTTACGCAGCGCGATGAGCACCCAGGCGCGTCCGAACGCTTTGACGTTGCCGTATTCCTGGCGAAGCCGCTTCGCGATCTCGAACACGCTACGACCTTCGAGCGAGAGAGCAAACATGCGGCGCACCACCACGGCGTGCTCCGGAACCACGCGGAGTGGCAGCGGCATCTTCGTTCCTTTGGGCTTCGGCTGGCGTTCGTAGCCGAATGGCGGCCGTCCCTCGACGAAGTAGCCTTGGACGCGCAGGTGCTTGCGCCCCCCTTCGGTCCGCTCCTTGATCCGACGGCGCTCCTGTTCCGCGCCGACCGCCCAGTTGGCCAGCGTGTCCTCTGCCATCGGCGAGCGTGAATCGAACCCCTTGTCAATGGCGACGAACACGGCGCCCTTGCGCATGATCTGCCGGACGTTCTTCACGATGAAGACCACGTCGCGGCCGAAGCGGTCGATGTCCGTCACGATCACCATGTCGCCGCGGCGGACGTCGGCCAGGAGCGCGGCGACCTTCTTCCTGTTCGCTTCGTTCTCCTCGCCGCCGCTCTCGACTTCCGGAAACAAGATCGGCTCCGGCAGCGAGTGGAGCCGGCAGTAGTTGCCGATCTTCTCGGCCTGGGCGTCCAGGGACACGCCCGCGATTTCCTGCTCCCTCGTTGACACGCGCGGGTAGCCAAGCGTCCGACGGATCGCGGTGTTGGGGGTTGCGTCTTTCATTTGTTGCACCTGTCCCAAAGGATGATCCTACTCCGGCCGGCCAAACTGAGCAAATCGCCGGTTTCAGCCGGAATTTCCGCCTCTCTTGCGTCTAACAAAAGCTCCGCAGCTCTGGAAGAGCGGCGTCCTGGCCCTGCTGGGCGAGGAGGCGGCGCGTTCGGACGAGCTGCTCGCGGATCTCATCGAGCGCGAGATCGTGGCGCGGCGGGGCGAGCATCGCTTCGCAGGGGAGGAGGAATACGCGTTTCAGCACGCGCTGGTCCGGCAGGCAGCCTACGCGATGCTCCTGGATCGCGACCGTCAGGTCGGCCACGGGCTCGCGGGGGCCTGGCTCGAACGCGCGGGCGAGCCGGATCCTGTCGTGCTCGCCGAGCATTTCGAGCGAGGAGCGGTCCGAGGGAAGGCGGCTCTCTGGCACGCGAGGGCGGCGGAGCGCGCGCTGCGGAGCCTGGATCTGGCGCCGGCGCTCTCTTCTGCGCGGCGCGGGCTCGCGATGGAGCCGGAGGGGGAGCTCTTGCCGGAGCTGTGGGTGCACGTGACGGAAGCCGCCGCGTACACGGGGGATCACGCGGAGGCGATGAAGGCGGCGGAAGAGGTGATGGCGCGGGCGAGCGTCGGCTCGTCGACGTATTGCCGAGCGCTGGGGCTCGCCCTCCTCCTGGCGCTGATGCTGCGTCGCCCCGAGGCGCTCTCCACCCTCATGGATCGGCTGCTCAGGACCCAGCCGGCGGCCGACGCCATCATGTCGCTGGCGCACGCGCTCTCCACGGCGGTGTTCGTGCTGCTGATCGGGGGGCAACGGGACGCGGCCGCGCTCTTCCTGGGGCGGCTGCGCGCGATCGCTGCGCCCGTCGTGGAAGAGGACCCCTCCGTCAAGGCCTACGTCGACGAGGCGTCGGCCTTCTGGGAGTCCTATGTGGAGCGGAACCCGTGGGCTGCGATGCGGCTGCACGCCGCCGCCGGGCAGCGGCTCGCGATCGCCGAGGACCTGCTGAGCATGCCCCACTCCATCGCCTTCATGGGATGGGACTGCGCGACGCTCGGGGCGTTCGAGGAAGCGGAGGGCTGCGTGGAGCGCGCGCTGTCGCTCTCTCGATCCGCGCGCGCCAACGTGCCGCTCGCGCGGCTGGTCATGGCGAACGTCCGCCTCGGCGAACGCCGGCTGGACGAGGCGGTCGCGGCCGCGACGGCCGCGCTGGGAGAGGCGCTGTCGCAGAGCGAAGGGGTGATCATCATGGCGGCGCAGCTCGCGCTCGCCGAGGCGCGGCTCCTGCGCGGGGAGTTCGACGCCGCCATGGAGGTGCTCGGCGGCTCCAGCGCGGGGACATCGGGGCTCGTGACGGTCGACGCCATGGCGCGTGGGCTCCGGGCGAAGATCCTCCTCGCCCGCGGTCGCGCCGGGGAGGCGGCGCGGGAGGCGGAGCAGGTGGTCGCGCTCGTCCGCGGCGCAGGCGTCTACGACGCGCGCCACGCGTCCCTCCTGCTCACGCGCGCGGAGGCGCTCGACGCCGCTGGCGAGGCCGAGGCGGCGCGCGCGGCCATCCGCGAGGCGCGCGAGGACCTGCTCGCCCGGGCCGCGCGGATCGAGGATCCCGCCTACCGGCGGAGCTTCCTCGAGCGCGTCCCCGAGCACGCCCGCACGCTCCTCGTGGCGCGCGCGTGGCTGGGGGAGGAGGATTGACTTTCGGATCGCGTTTGGATTTCCTGGCCCCTTCACGGTTTGGCTGCGCTGATTCTCGGCCCATCGCCATGCCAGTCGATTCCTCGCCGCGGCAGAGGTAGTTCCCATGCTCATCGTCGTGCTCTTTCATGACGCCGACCGCGAAGTCTTGGAAAGGCTCGAAACGCATCTACAGGCCGCTCTTCGGAGCGGAGAAGCACGGCTGTGGCACCGTGACAAGATCTTACCAGGTCAAGACCAGGACCTCGCGCTCAAAGAGTCGCTCAAGGAAGCATCGGTCTTCATACTTCTATTGAGCGCCGACTTCAATGCGTCATGGAACAAACATTCCTATGAGACCGTGCTCGTGCGGGGCACGTCGGCTCGCCAATTGCCCCTGGTGGTGCCAGTCCTCGCGAAGCCTTGCATACTGAGCGGACTGCCCTATGCCAGGCTGCGTTGTGTGCCACAGAACGGGCAACCGCTATGGCGCGATGGGCGCCTTGACGAGCATCGCCTGTATCTCGCGGCCACAGAAATTCTCAACAGTGTGGAGGAGGCATACGAACGGTTGTTCTCCGAGCACGCCGAGACAAAGACCGATATACCTAACCCCGATCTGTATGAGCTCATCATAACGTCTGAGCGTGAGCGATTCCGACTCGAGAAAGCGCTGGATAGCCAAAAAGCCACCAGCGCGACCGCGCAGATTGACGCGACCGGGTCATCGATATTGAGTGATGAGACGAAGGACGAGCGCAATGACGCGTACAGGCGCGGCATCGCCGAGGGTGAGCTCATGGGTAGGCGCACGACGCTGCTGCGCCTCGTGGCGCGCGCTGGGATTCCCCTCACGACGAGCGATCTCTCTCGTATTCAGGGGTGCGGTGACGTGGCGACCCTCGATCGGTGGATCGACAATAGTCTCAGTGCGAAGACCGCGGCCGATGTCCTCTCGTTACGTCGGCTCGCGTGATGGCTCCCGCAGAGCGGGCCGGCTCCGAAGCTGCGCGCGGCCAGCGCCGCGCGCGCCGCGGCCACGTCGGGCGGCGAGCAGAGCAGGAGCGGATCGAGGTTGCCCTGGATCGCCCGATCGCAGCCCGAGCTCAGCGCGGCGCTCGCTTCGTGGCCTCCCACCGCTCCAGCGTGACGACGAGTCGAGCCGCCCCGAGGATGCCGGCCGGGAGCACGATGAGCAGCGAGCAAGGCAGGAACGAGAGCAGCGCGAGTCCAAATCCGAAGCCCATCACCGCGGCGAGGTTCCGGCGCACGAACTCGATCCGCGCCGCCACGGGCACGCCGCGGATCGACAGCGGGCAATCGCAGAGGTCCCAGGCCCCCGCGAGCGCCGCCACCGCGAGCTGAAGCGGGACGACGACGACGCTCGCCGGCGCGAAGAGGAGACCCACGACGCCGAGGACGATGAGGATCGGGAGCGTGAAGGCGAGCGCCACGAGCGACGACTGCAGCGCGCGCCACATGTCCGCGAAGAAGCCGACCTCCGGCCACGCGGGCGCCCCGAGATCGGCCTCGGCCCTGCGCACCATCCGCTCCAGCGCGGGCCCCGAGAGCGGCTTCGCGAGCCCGAACGAGAGGGCGAGGGCGGCCACGAGCACCACCGCGAGCGAGAGGACCCGCAGCGCGGCCATGAGCACGGTCCAGAGCCACCCCGTCCCCGGCTCCTTCACGATCAGCTCGACGAGCGAGGGCGCGACCTTCACGCCGGCGATGGCGAGCACGACCGTGAGCACGAGCGCGAGGCTCGTAGGGACGAGCGCGAGCGGCCAGAGGTCCGGCGTGCGAAAGAGGTAACCGTAGCCGCCCAGCATGGCCTTGAGGCCCGCGCCGAAGCCGGGGCGCTCGAGCGGCGCGAGCCCCGCGGGCGGGCGCTGCGCGGGCGCGGTGGGAGAGCCGAGGGGAGCGTCGGGGGTGATCATCCGGCGACGAACGTCTCAGCGGTCGGGCATCCGGTCAACGCCTCCCGCGCGCTAGACCCGCTCCTCCCCGCCCCGGGGACACGCCCCCAGCGCGGCGGCGGGCTCGCCCGGCGCGCCGCGGCGCCGCGCCGGAGGGCGCCAGAGCGACTCGGCGACGCCGAGCAGGACGTAAGCGCCGATCAGCCAGACAAGGACGTACCCCGGCGCCCAGCGGGTCGAGATGAGCGCGCTCGAGCCGATGACGAGCGCGATCGACAGCGCGGCGCGGGCGTCGAGGCGGACATCCTTGAACGAGCGGAATCGCAGGGTCGACACCATCAGGAGCGAGAGGAGCAGCGTCGTCGCGAGGACCGCCGGCGCGACGCCGACCCCGGCGAGCTGCCCGTCCTCGAAGCCGTGGGTCATGACGATCGCGACGAGGATCCCGGCCGCGCCGGTGACGGGGAGGCCGACGACGTACCGCGGCGGCGCCGACGAACCGCCCGCCTCGGCGAGGGAGAGGACGTTGAAGCGAGCGAGCCGGATCGCGCCGCACGCCGCGAACACGAACCCGCCGAGCACGCCGGCGAGGCCGAGGCGGTGCAGCGCCCACTGGTGCACGAGCACGGCCGGGGCCACGCCGAACGAGACGAGATCGGCCAGCGCGTCGAGCTCCCGCCCGAACGCGCTGTCGGTCCTGGTCATCCGCGCGACGCGGCCGTCGAGCGCGTCGAGGAGCATCGCGAAGAGGATGAGGCTCGCGGCGCGCCGGAAATCGTCGTCCGACCGCGCGGCGGCCGCGCGCCGTACCGCGTCCAGGCCGCAGAAGATGGATGACAGCGTGATCAGGTTCGGGAGGAGAAACAGCGCCTTTCCCGGGGTCCGCGGCGGCCGCCCCCGCGCCGCCTCGACGCGCGGCCGCTCGGGCCCCGCGCCTCGGCCTGGCCGTGGGCCCGGGGGGCGAAAGCGCGCGACGCCGCCGTCCCGTCTTCCTGGAGTGAGTGCTGACATGATGGGGCGAGGTCTTCCAGGCGCCGCCTGGCCGCGCGGCCCCTGGCCCGCGGCCCGACGGGCCCGCTCGCCCGGCCTCGTAGTACACGAGGCCACGCGCCTTCAAGCCGGGAGCGCGACGCCTTGCGCGCACGGCGCCCGCGCGCGCGCACGGCGCCCCCGGCCCGCGGCGAGGATCGCTAGCCCTGCAGATCGGTGCTGAGGAACACCTCGTGGATATCGAGCTTGCTCGGGCCCGCGAACATCTCCTTCGGCGCGCGGTTCCGGTGCGCCTCCGCGAACGCGGGGCTCCTCGTCCAGGCGATGAAGTCGTCCATCGACCGCCACCAGGTCTTGACCTCGTAGAACCCCTGCGCGTCCGGATCCGGGCTCCACGCGCCCGTCGCGTGGTCCAGCTTCATCGGCTTCGGCCTGTGCACCTCGTTCCGGAGGAAGCCGGGCGCGCGGTCGACCAGGTGCACCCGGTTCTTGAAGCGGTCCTCGAACTCGGCCTCGTGGCCCTCGGCGACGGGAATGCGGTTGGTGACGACGATCATGGCTCCTCCTTGCTGGTGCCCCGGGACCCGCCCCGGCGCGGGCGATGGCGAGCTTAGCAGCGCGCCCGCCCGGCCGGGACCGCGCCGCGCACGTTGCCCCCGTTCGCTGCAGATAATCTTAGAATTTCTCAGAGCTCATCGTAACGCAGTCAATGACACGCGACCGGTCACGTCCAGGCGGCAGCTCCGACGAAAACGGATTGACAAGTCCGCCTTTAGGAGCCCTCATCCCAGGAGGTCCGTTCATGAACGATTCCGAGACGGCTCGCGGCGCCCGATCAGCAGCGGGGCTCGATCGCTCCGAGATGGAGGGCGTGGTGCGCCGGAACATCCAGGCGCTCCTGCAGGTCCGGAAGGAGAGCGAGCGCAACAAGGGCTTCCAGGAGGCCCTCGCTGACGCGATCACCAAGTTCACGGGGAGCATGACGTTCGTCTTCCTCCACGCCACCGTCTTCGGGGGCTGGATCGTGGTGAACACGGGCGTCATCCCCGGCCTCAAGCCGTTCGACCCGTTTCCGTTCGTGATGCTCGCGATGATCGCGTCGGTCGAGGCGATCTTCCTCTCGACCTTCGTGCTCATCAGCCAGAACCGCATGCAGGCGCTCGCCGACAAACGCGCCGATCTCGACCTCCAGATCAACCTCCTGGCAGAGCACGAGGTCACCCGGCTCATCGAGCTCGTCGACGGCATCTCCAGGCACCTCAAGGTGCCCCGGACCAGCGACCCGCACCTCGAGGAGCTCAAGAAAGATGTCCACCCCGAGGTGGTGCTGGAGGAGATCGAGCGCGCGCAGCGGGATATAACGGAGTAGTCAATACGGACTCTCCCTAGAGGAGCACCGGCTTCGCCTGATCCCACGGTGAGGTGGCGTATCGCATGCTCCGTCGTCCGCAGACGGCGCGCCCACGCGCCGGAACGCCTCGGATCGAGCCCGAGGATTGTCCGGGAAATCACGGAGGTTTTTGGCGGGATTCAGCGCTCGCCAGCGCGACTCGAAGATCGTACTGCGGGTGATATTGTCAAATCTCTCACGAACCACTCTTGCAGGGTCGTGAGTTACATGTTACTCGGATGGCGTCCCGGGCGTCGATTGTACGATGTCCGCGCTGAACAGAACCGGGCACGGTGGCGCAGTGAGCCGTCCCGAGCGCGGCGCCGCCGCAAGGGCGTCCTCTTCTATAGCCTAGCCTCATCCGCGCAGGCTCGTGGCGTTTTGCCACGCATTCACCATCGACCCAGAGGAATATGGCCAGTCACGTCCTCATCACCGGTGGAGCGGGCTTCATCGGCTCGCACGTCGCCGACGAGCTCCTGCGCCAAGGGCATCGCGTCCGGGCGCTCGACAACCTCATCCCGCAGGTGCACGGGCCCGAGCGCCGGCGCCCGGCGTACCTCGACCCGGAAGTCGAGCTCATCGTGGGTGACGTCCGGGACCGGGACGCGGTGAAGTCGGCATTACGCGGCGTGGACGTCGTTTACCACTTCGCGGCCATGGTCGGGGTCGGACAGAGCATGTACAAGATCGCGGAGTACACCTCGGTCAACAACCTCGGCACCGCCGTGCTCCTGGAAGAGCTCGCCGAGAGGCCGGTCTCGAGGCTGATCGTCGCGTCCAGCATGAGCGTGTACGGCGAGGGGCTCTACCGGACCGCCTCGGGCGCCGTGGTCCCCGGCGCGGGCCGCCCGCTCGATCAGCTGAAGCGCGGCGACTGGGAGGTCCGGAGCGAGGCGGGCGAGGCGCTCGCGCCGATCCCGACCCCCGAGTCCAAGACGCCGGCGCTCGAGTCGGTCTATGCGCTCTCCAAGTACGATCAGGAGCGGCTCTGCCTGACGATCGGACGCGCCTACAACATCCCGACCGTCGCCCTCCGCTTCTTCAACGTGTACGGCCGCCGCCAGGCCCTCTCCAACCCGTACACCGGCGTCCTCGCCATCTTCGCCTCCCGGCTCCTCAACGATCGTCCGCCCCTCATCTTCGAGGACGGCCTGCAGCGGCGCGACTTCGTGAGCGTCGCCGACATCTCCCGCGCCTGCGTCCGGGTCCTCAGCGCCGACGCCGCGGTGGGCCAGGTGCTCAACATCGGCAGCGGGCGGTCGTACACCGTGCGCGAGGTCGCCGATCACGTCCGCAAGGTGATGGGGAAGGACCGGATCGAGCCCGAGATCACCGGGAAATCGCGGCTGGGCGACATCCGGCACTGCTTCGCGGACATCGGCGCGGCGCAGCGCAAGATCGGGTATGAGCCCCAGGTCACCCTCGAGGAGGGGCTCCGCGATCTCGCCGGCTGGCTCGAGGGCCAGGTGGCGAAGGACGCTGTCGCCCAGGCCCGCGCCGAGCTGGAGTCCCGGGGGCTGACGGTATGAGCGCCGCGGATCTCGATCCCCGCGGCGCGGCCGGGGAGCCGGGGCGACCGGCGCTGATCACCGGCGGCGCCGGCTTCATCGGGTCCAACGTTGCCCACCGCCTGCTCCAGGCGGGAGAGTCGGTGATCCTCTTCGACAACCTCTCGCGGCCCTCCGTGGCGCGCAACGTGGACTGGCTGAAGCGCGTCCACGGCGACCGCGTCACGCTGGTCGCCGGCGACGTGCGGGACGCCGTCGCGGTCGCCGAGGTGGTCCGGCGCGCCTCCAGCGTCTTTCATTTCGCCGCCCAGGTCGCGGTGACCACCAGCCTGGTCCGGCCGGCGGAAGACTTCGAGATCAACGCCCGGGGGACGCTCAACGTCCTCGAGGCGATCCGCGCCCAGAGCGCCCCGCCGCCGCTCCTCTTCACGTCCACCAACAAGGTGTACGGCGGCCTCCCCGACGTCCCGCTCCAGCGCAGGGATCGGCAGTACGCGCCCGAGGATCCGAAGCTCCGCGCCGCCGGCATCTCGGAGGCCCGGCCGCTCGACTTCCACAGCCCCTACGGGTGCTCGAAGGGCGCGGCGGATCAGTACGTGATCGATTATGCCCGCACCTTCGGGCTCCCCGCGGCGGTGTTCCGGATGAGCTGTATCTACGGGCCTCGCCAGTTCGGGACCGAGGACCAGGGGTGGGTGGCTCATTTCCTCCTCCAGGCGCTCCGGCGCGAGCCGATCACCCTCTACGGCGACGGGATGCAGGTCCGGGACGTGCTGTTCATCGACGATCTCGTCGACGCCTTCCTCCTCGCCCGCAAGAACATCCGGCAGGTCTCCGCGACGGCGTTCAACATCGGCGGCGGCCCGGAGAACACTGTCAGCCTGCTCGAGCTGCTCGACCTCATCGAGGAGCTCGACGGCAAGCGCCCCGCGACCGGCTTCGAGGCGTGGCGCCCCGGCGATCAGCGCTACTACGTCTCCGATTGCCGCCGGTTCAACGCGGCGACGGGGTGGTGGCCGCGCGTCCGGTTCCGCGACGGCGTGCGCAAGCTGCACGGCTGGCTGCGCGAGATGACCGGCGCCGGCAAGGCCGCCGGGCAGGCGGCCGAGGAGCTCTGCATGGAGGGCGCCGAGTGAGGTTCGCGCTCGTCAACCCGCCCTGGAGCTTCGAGGGGAGCATCTATTTCGGCTGCCGCGAGCCCCACCTGCCGCTCGAGTACGGCTACGCCAGGGCGCTGCTCGAGGCCGCGGGGCACGAGGCGGCGCTCGTCGACGCCCAGGCCCGGGGGCTCTCCCAGGCGGCGCTCCGCGACGAGGTGGCCGCGCTCCGCCCCGACGCCATCGTGGTGACCACCGCGCCGAGCTACCTCTTCTGGCGCTGCGCCCCGCCCGAGCTCCGGGTCCCGCAGCAGACGCTCCACGCCCTGCGCGACGTGCCGGGCCTCCGGTTCGCGGTCGGCCCCCACGCCTCCACCACCCCCCGCGCCACCCTGCGCAAGCTCGGGGTCGACGCGGTGGTGATGGGCGAATGCGAGGAGGTCCTTGTCCAGCTCGCGGATCTGCCGCGCGCGCGCTGGGGCGAGATCGCCTCGATCGCCTATGTCGAAGGCGAGGAGGCGCGCGTCCAGGGCGGGCCGCGCGCGTCCGACATGGCGCGGCTCCCGGCCCTCCGCTGGGACGACGCGACGGTCGCGCGCCACGCCCACCACCACCACCGCTTCGACGCCGCGCCCGTCGGGCCGGGCGCCGAGATCGAGGCGTCCCGCGGGTGCCCGTACCACTGCACCTTCTGCGCGAAGGACAACTTCCGCGATCGCTACCGCAAGCGGCCGCTCGCCGTGCTCCTCGACGAGCTCGACGGGCTCGTCGCGCAGGGCGTCCGCTACGTCTACTTCATCGACGAGATCTTCCTCCCGGACCGCCCGCTGCTCGAGGCGCTCGTGGATCGGCCGGTGTCGTTCGGCATCCAGATGCGCATCGACAACTGGAGCCGCGAGATGCTCGACCTGCTCGGGAAGGCGGGGTGCGTCTCGATCGAGGCCGGCGTGGAGAGCATCACGAAGGAGGGCAGGAGCCTCCTGGCCAAGCACTGCAGGCTCTCGACCGAGCAGCTCAGCGACCTCCTGATCCACGCCAAGAAGAGCGTCCCCTTCGTCCAGGCGAACCTGATCCAGTCGCAGACCGACGATCCCGCGGACGTCGCCGCCTTCCGGGAGCGGCTCCGGCAGCACGGCGTGTGGGCGAACGAGCCGGTGCCGATATTTCCCTACCCCGGGTCGCCCGATTACACGACGCGCTGGGGCCTGCCGGACGATCAGGCGTGGGAGCGCTCGGTCGCGCACTACCTCGGCCAGTTCGATCACTTCAGCGACCTCCAGGAGAGCCGCCCGCTCCCGCTCTCCGAGCTCGAGGTCGCGGCGCCCGGCCATGGTTGACGCCCTGCCCTCCCCCGGCTCCGTCCTGATGACCGCCGACACGGTGGGCGGCGTCTTCTCCTACGCGATCGAGCTCGCGCGCGCGCTCGCGGAGCGCGGGGTCCGGACGTCGCTCGCCACCATGGGCGGGCCGCTCTCGGCGCCCCAGCGCGAGGCCGCGGGCCGCGTGCCCGGGCTCGCCGTCTTCGAGAGCTCCTTCCGGCTCGAGTGGATGGACGACCCCTGGGACGACGTCGCGCGCGCCGGGGACTGGCTCCTCGAGCTCGAGGAGCGCGTCCGCCCGGACGTTGTCCACCTGAACGGCTACGCGCACGGCGCCCTCGGCTTCCGCGCCCCGAAGCTCGTGGTGGCCCACTCGTGCGTGCTCTCCTGGTGGACCGCCGTCCTCGGCGGGGAGGCGCCGCCGCGGTACGATCGCTACCGGCGCGAGGTGGCCCGCGGGCTCGCCGCCGCCGCCGCGGTCGTGGCGCCGACCCAGGCGATGCTCGACGCCCTCGTGCGCCACCACGGCGCGCTCGCGCCCTTCCGGGGCGCCCGGGCGGCGGTGATCCCCAACGCGGCCGACCCGGACCGGTTCGCCCCGGGCCCGAAGGACGAGGTCATCGTCGCGGTCGGACGGCTCTGGGACCAGGCCAAGAACATCGCGGCCCTCGGCGAGGTGGCCCCTCGCCTGCCCTGGCCGATCCAGGTGGCCGGGAGCGACGTCCACCCCGGCGGGGGCAGCCGGCCCCTCCCGTCGCTCGAGCACCTCGGCGTGCTCTCGCCGTCCGGCGTCGCCGCCGCGCTCGCCCGCGCCTCGATCTGCGCGCACCCCGCCCGCTACGAGCCGTTCGGCCTGTCGGTCCTGGAGGCCGCGCTCTCCGGCTGCGCCCTCGTCCTCGGCGACATCCCCAGCCTGCGCGAGGTCTGGGGGGACGCGGCCCTCTACGTCGATCCCGGCGACACCGAGGCGCTCCGGCGCGCGCTCGCGGCGCTCGTCGACGATCCCGTAAGGCGGCAGGACATGGCGTCGCGCGCCCGCGCCCGCGCCGCCGCGTTCTCGCCGCGGCGGATGGCCCGGGGCTACCTGCACCTCTACGGCGAGCTCCTCGGGGGCAGCTCGCGAACGAGGCGCTCGCCGGCGCGCGAGGCGCCGCGCGCCGCCGCCGTGGGAGGCGAGTGAGCCATGCGCATCGTCCTGTTCTGCCACTCGCTCCTGTCCGACTGGAACCACGGCAACGCGCACTTCCTCCGGGGCGTGGTCACCGAGCTCACCGAACGCGGGCACGAGGTCCGCGTCTTCGAGCCGCGCGACGCGTGGAGCCTCCAGAACCTCGTCGCCGACCACGGCGAGGCCCCGCTGCGCGAGGTGCGCGACGTCTACCCGCACGTCGACCCGATCCGCTACGACCTCGCCTCGCTCGACCTGGACGAGGCGCTCGAGGGCGCCGCGCTGGTCATCGTCCACGAGTGGAGCGAGCCGGAGCTGGTCGCCCGCGTCGGCGCCCACCGGGCCGGCGCGTCGTACCGGCTGCTCTTCCACGACACGCACCACCGGTCGGTCACCGATCCCGGCGCCATGGCCCGCTACGACCTCACCCACTACGACGGCGTCCTCGCCTTCGGCCGGGTGATCCGCGACCTCTACCTCGAGCGCCGCTGGGCCCGCCGGGCGTTCGTCTGGCACGAGGCCGCCGACGCGCGGGTCTTCCGCCCGCGCCGCGAGATCCAGCCCGAGCGCGATCTCGTGTGGGTCGGCAACTGGGGCGACGAGGAGCGCACGCGCGAGCTCGACGAGTTCCTCATCGGCCCGGCGCGCGACCTCGGCCTCTCCGCCCGCGTGCACGGGGTGCGCTACCCCGAGCACGCCCGCGCCGCGCTCGAGGCGGCCGGGGTCGAGTACCGCGGCTGGCTCCCCAACCACCGCGCGCCCGACGCGTTCGCGCGGGCGCGGGTGACCGTCCACGTGCCGAGGCGGCCCTACGTCGCGTCGCTCCCGGGCATCCCGACCATCCGGCCGTTCGAGGCCATGGCCTGCGCCATCCCGCTCGTCTGCTCGCCGTGGAGCGACGCGGAGGCGCTGTTCTCGCCCGGGCTCGACTACCTCGTCGCCCGCGACGGCGAGGAGATGAAGAAGCACCTCCGCGCGCTCCTCGCCGAGCCCGCCATGGCCGCCGAGCTGGCGGAGCGGGGGCGCACGACGGTCCTCGCCCGCCACACCTGCGCCCACCGCGTCAACGAGCTCCTCTGCATCTCGGCCGACCTCGGCATCGAGGTCGACCGCCCGGCGCCCGCCGCCACCACCCAGCGAGCCACCGCATGAACCGACGCCCGACCTCGAGCCGACCGCTCGACATCGCCTTCTTCGGATCGAGCCTCGTCTCCGCCTACTGGAACGGAGCGGCCACCTACTACCGCGGCATCATCCGCGCCCTCGCCGCGCGCGGGCACCGCGTCACCTTCTACGAGCCGGACGCGTACGACCGGCAGAAGCACCGCGACATCGACGATCCGCCGTGGGCCCGCGTCGTCGTCTACTCCGGCACCGACGCCGACGAGCCGAGGCGGCTCGTCCAGCAGGCGCGGAGCGCCGACGTCGTGGTCAAGGCGAGCGGCGTCGGCGTCTTCGACGAGCTCCTCGAGGCCGAGGTCGCCGCGCTCGATCGGCCGGGGCTCACCACCGTCTTCTGGGACGTCGACGCCCCGGCCACGCTCGAGCGGGTCCGGGCCAGCGCGTCGGACCCGTTCCGCGCGCAGATCCCACGCTACGGCCTGGTCTTCACCTACGGCGGCGGCGACCCCGTGGTGCGCGGCTACGAGGCGCTCGGCGCCCGGCGCTGCGTGCCGATCTACAACGCGCTCGACGCCGAGACCCACTTCGAGGTCGCGCCGGATCCACGGTTCGACTGCGATTTCGCGCTCCTCGCCAACCGCCTCCCGGACCGGGAGCGGCGCGTGGAGGAGTTCTTCCTGCGGCCCGCGGCCGCGCTCCCCGAGCTCCGGTTCCTGCTCGGCGGCAATGGCTGGCAGGACAAGGCGATGCCCCCGAACGTCCGGTACGTCGGGCACGTCTACACCGCGGATCACAACGCCTTCAACGCGAGCGCCCGCGCGGTGCTGAACGTGGCCCGCGACAGCATGGCGTCGGTCGGCTTCTCCCCGGCGACGCGGGTCTTCGAGGCCGCGGGCGCGGCCGCGTGCCTCGTCACCGACGCGTGGGAGGGGATCGAGCTCTTCCTCGAGCCCGAGCGCGAGGTGCTCGTCGCGAGGGACGGCGACGAGGTCGCGGCGATCCTCCGGGCGCTCACGCCCGAGCGGGCCCGCGCCATCGGCGAGGCGGCGAAGCAGCGCGTGCTCGCCGGGCACACCTACGCGGAGCGGGCGAAGCAGGTCGAGGCGCTGCTCGGCCGCCCCGACGGCGCCGCCGACGCCGCCGACGCAACCCTCACCGCGATCGCGCCGTGAAGACCCTCTCCTTCGTTTTCCTGGGCCTGTCGATCACCTCGTCGTGGGGCAACGGCCACGCGACCACGTACCGCGGGCTCCTCAAGCGGCTCGCCCAGCGCGGGCACCGCGTGCTGTTCCTCGAGCGGGACCTCTGGTTCTACGCGGAGAACCGCGATCTGCCGGACCCGCCGTACGGCCGGACCGAGCTCTACCAGGGGCTCGACGACCTCCGCGCGCGCTTCGGGGACGCGGTGCGCGACGCGGACATGGTGGTCGTCGGGTCCTACGTGCCCGACGGGGTCGAGGTCGGCGCCTGGGTGACGGAGACGGCGCGCGGGAAGACCGCGTTTTACGACATCGACACGCCGGTCACGCTCAAGAAGCTCGAGCGCGGAGACACCGAGTACCTGTCGGCGGCGCTGATCCCGCGCTACGACCTCTACCTCTCGTTCACCGGCGGCCCCACGCTCGACCTGCTCGAGCGCCGCTACGGGGCGAAGCGGGCGCGCCCGCTCTACTGCTCGGTGGATCCGGACGCGTATTTCCCGGAGCGCCGCTCGCCCCGCTGGGATCTCGGCTACCTCGGCACCTACAGCCCCGATCGCCAGCCCACCTTGGATCGCCTCCTCGTCGAGCCGGCGCGCCGCTGGGCGCAGGGGCGCTTCGCGGTCGCGGGGCCGCAGTACCCGGCGGACATCGACTGGCCGTCGAACGTCGACCGGACGGATCACATCCCGCCCGGCGAGCACCGCGCCTTTTACGGCGCGCAGCGCTTCACGCTCAACGTCACCCGGCGGGACATGATCGAGGCGGGGTACTCGCCGAGCGTGCGCCTGTTCGAGGCGGCGGCCTGCGGCGTGCCGGTGATCAGCGACGACTGGCCGGGGCTCGACGAGCTCTTCGAGCCGGGCAAGGAGATCCTCCTGGCCCGCTCCTCGGAGGAGGCGCTCCGCCTGCTCCGCGAGTTCCCCGAGCGGGAGCGGGTCGCGATCGGGCAGCGGGCGCGCGAGCGCGTGCTCGCCCGGCACACCGCAGCGCACCGCGCCGAGGCGCTGGAGAGATACGCCCGGGAGCTGCTCCACGAGCAGGACGAGCGGGAGCTCCCAGGGGACCGGGGTTCGTGAACGTGTGGTGTCGGCTCGAAACAGCGTGCTGCAAATGAAGGATGACGAAGCGACCGTGGCGCGGAGGAACCCCATCGCGCCCACCCGCGCCGGGGCGGTCGTCCGGTCGTCGTCGCGTGGAGAGGAGGTCAGAGAGACATGAGCGCTGCGCTGCGCATCCTGGTGACCGGAGGCGCCGGCTTCGTCGGCTCCCACCTGTGTGATCGGCTGATCCGCGACGGCCACGAGGTCATCGCGCTCGACGATTTCTCGACCGGCGCCCGGGGCAACGTCGCCCACCTCCTCCTCCATCGTCGCTTCCGGCTTGTGGAGCACGACGTCACCCAGCCGTACGATCTCCAGGTCGACCGCATCTACAACCTCGCCTCGCCGGCGAGCCCGCCGCATTACCAGCGCGATCCGGTGCGGACCACGCTGATCAACGTGGTCGGCGCGTTCCACGCGCTGAAGCTCGCCGAGGGCTGCGGGGCGCGGGTGTTCCAGGCGTCGACGAGCGAGGTCTACGGCGATCCCGAGGTCCACCCGCAGCCGGAGGGCTACCGGGGCTCGGTGAACCCGATCGGGATCCGCTCCTGTTACGACGAGGGGAAGCGCTGCGCCGAGTCGCTGGTGATGGACTTCCACCGTCGCCGCGGCGTCGAGGTCCGGATGGCGCGGATCTTCAACACCTACGGTCCGCGGATGGCGCTCGACGACGGGCGCGTGGTGTCGAACTTCATCGTCCAGGCGCTAAAGGGCGAGGATCTGACGGTCTACGGCGCCGGCTCGCAGACGCGGAGCTTCTGCTACGTGGACGATCTCGTCGAGGGGATCGTGCGGCTGATGGAGCACCCCACCGAGACGGGCCCGGTGAACCTGGGCAATCCGGAGGAGTTCACGGTGCTGGAGCTCGCCGAGGAGGTGATTCGCCTGACCGGGAGCCGGAGCCGGATCGCGTTCCGCCCGCTGCCGCAGGACGATCCGCGGCAGCGGCAGCCGGTCATCGATCATGCGAAGCGGGTGCTCGGCTTCGAGCCGAAGGTGCCGCTGCGGGCGGGGCTGCGCCGGACGATCGAGGGTTTCCGGAGCGTGCTCGGGCTGGGCCGGCACGCCCCTGCGCTGGCGGCGTCGGAGGGCGACGCGGCGCTGCCTCAGGCCGCGAACGGCTGAGCGGCGCCGCGCGCGCCGGGCGTTCGTCGAGACGAGCCGTGAGCGGCCGAGCTGGCCGCGTGTGAGGAGAGATCGGATGAAGCAGCCGCAGAAGCTGGCGAAGCCCGAGGGGAAGCTGGCCGTGCTCCTCCCGGGGCTCGGGGCGGTGTCGACGACGACGATCGCGGGCGTGATGCTCGCGCGGCGGGGCGTCGCCGCGCCGGTGGGGGCCTTGACGCAGCTCGGGACGATCCGGCTGGGGAAGCGGACGGACAACCGCTCTCCGAGGATCAAGGACTTCGTCCCGCTGGCGTCGCTCGATGATCTGGAGTTCGGCGGCTGGGACATCTTCCCCGACAACGCGCACGAGGCGGCGGTGGAGGCGAAGGTGCTCGAGGCGGCGCACCTCGATGCCGTCCGCGAGGAGCTCGCGGCCGTCACGCCGATGAAGGCGGTGTTCTACCCGGACTACGTGCGCCGGCTGCACGGCCCGCACGTGAAGACCGGCCGCAGCAAGGCCGACATGGTGGAGCAGGTGCGGGACGACATCCGCGGCTTCGTGCGCTCGCGCGGGGCGAGCCGGGCCGTGGCCGTGTGGTGCGGCTCGACGGAGATCTTCATCGCGCCGTCGGAGGTGCACCGGTCGGCGGCCGCGTTCGAGGCGGGGCTGCTCTCGAACCACCCGGCCATCTCGAACTCGCAGATCTACGCCTGGGCGTGCATCAAGGAGGGTGTCCCGTTCGCCAACGGGGCGCCGAACCTGACCGTGGATTTCCCCGCCGCGTGGGAGCTCGCGCGCAGCCACGGCGTGCCGATCGCGGGCAAGGACTTCAAGACGGGGCAGACCCTGATGAAGACCGTGATCGCGCCGGCGCTCAAGGCGCGGATGCTCGGCATCTCGGGGTGGTTCTCGACGAACATCCTCGGCAACCGCGACGGCGTGGTGCTGGACGACCCGGACTCGTTCAAGACGAAGGAGGCGTCGAAGCTCAGCGTGCTCGAGCAGATCCTCCAGCCGGAGCTCTACAGGGAGCTGTACTCGAAGCTCTACCACAAGGTGCGGATCGAGCATTATCCGCCGCGCGGGGACGCGAAGGAGGGGTGGGACAACATCGACCTGTTCGGGTGGCTCGGCTATCCGATGCAGATGAAGGTGAACTTCCTCTGCCGTGACTCGATCCTCGCGGCGCCGATCGTGCTCGATCTGGCGCTGCTCCTCGACCTCGCGGCGAGGGCGGGGTTCAGCGGGACGCAGGAGTGGCTGAGCTTCTACTTCAAGAGCCCGATGACGGCGCCGGAGCTCTACCCGGAGCACGACCTGTTCATCCAGTCGATGAAGCTCAAGAACACGCTGCGCTGGATGATGGGGGAAGAGCTGATCACGCACCTCGGGAACGAGTATTACGACTGAGGCGGCGATGCTGCGATGCCGAGCTCTCAGCGCGCGGGCGCCGGCTCGCGAGGCTTCGAGAGCTGATGATTGAGGTGACTGCGCACCGTGGGCCATTCCGGGGCGATGATGCTGTATACGCACGTGTCGCGCAGCGTGCCGTCGGACGCGCGACGATGGCTGCGCAAGACGCCGTCGAGCTTCGCGCCCAGGCGCTCGATGGCGCGCCGGCTCTGGTGGTTGAAGAAATGCGTTCGGAACTCCACCGCGATGCACTCCAGCGCCTCGAACGCGTGTTGCAACAGCAGCAGCTTGCATTCGGTGTTGATCGCGGTGCGCTGCACGCTCTTGCGGTACCACGTCGAGCCGATCTCCACGCGCCGATTGGCCGCGTCGATGTCCATGTACGTGGTCATGCCGATCGCGCGTCCGCTGCGCGCGTCGATCACGACGAAGGGCAGCATCGAGCCCGAGCGCTGAAGGGACAACCGACGCTCGATCTCGTCGCGCACGCCTTCGGGGCGCGGGATGTAGGTGTACCAGAGATCCCACAGCTCGCCGTCGCGCACCGCGTCGACGAGATCATCCTGGTAAGCGTGGGTCAGCGGCTCGAGCGCGGCATGGCGCCCGCGCAAGGTGACGGGTTCCGGCCAGGGCATGCGAATTCCTTATTGGGTGGGGAAACTACATTTCACGCAATGGGGTTGCTTGTCAATCGGTTCCGGCCGAGGCTCGGCCGCGCGCGCTTGCGGCGTGGCGCAACACGGGCCCGGCCGGCCGCCTCCGGCAGCTTCGCGGTCCGCCTCAACGGGGCTTCTCGGGGGGCCGGATCGCCTTCGGCTCTTTGCGTCGTTCCGGCACGATGGTCTCCCCGCGCGCCAGCATCGCCACCAGATCGGCGATCTTCTTTGCGCGGCCGGCGGGCGTCTTCATGTTGCTCATGCGGAACGCCAGCGCGAACAGGTTCTGACGCCCCAGCGTCTGGAGCGCCTCGCGCGCCCGCGGGTTCGCCTCGATCGCGGCGCGAAGGTCGTCCGGCAGGGTGGCCGCGGTCGCGCTGCGCATCGGCGCGTACGCCGCATCCCAGCGGCCGTCGGCCTTGGCCGCGTCCACCTGCCGCTGCCCGTGGGGCGTCATGCGCCCCGCGGCGGTCAAGCGGGCGATGTGGTCGCGGTTGATCTGACTCCAGACGCTCCTCGACTTGCGCGGCGTGTACCGCTGCAAGAACGAGCTTTCATCCAGGGATTTTCGGATGCCGTCGATCCATCCCCAGCAGAGCGCCACGTCGAGCGCTTGCGCCTGGGTCACCGTCGGCACGCCGGAGCCCTTCTTGTAGATCCTCAGCCACAGCTCCGTCTCCTGCGCGTGGTTCGCGGCCATCCACGCCTCGAGCTCGGCTTCGGTGGGGAAGCTCTTGATCTTCTTCTTATCGGGGGTGATCGATGCCATGCAGTCTGCCTCGCAGCGTGTTCATCTTACGGCGAACCTGCAGAGGCCGATAGCGCCGCGCAGCGGCCAGGACGACGGCGGCGAGGACGACGCTCCCGGCGCTCGTGGCGCTGGAGGCCGCCTTTAGCCTCGAGGCCGCGCTGCGTCAACGCAGCCCGGCGGCGAGCTCCGCGGGTCATCCAGCGGCCGGCCCCACCGCCGCGCATCCGCTGCGCGTCGTCGTCGAGCGGAGCGAGCCCGGGCCGTCGTTCGTTGCGGGCCTGGGCGATCCCGCCGAGGAGCGCGCTGGCCGTCCGATCGTCCTGTTGATTCTTCACTCTCGCCTCGGTAACAGACGAGGAGCATGAGGGAACGATCCGCGCGATGGCTGTGGGCGGCGTTGTGCCTGCCGGGCGTCGGCTGCACGACGGTCGTCGGGCTGGACAAGCCCTATCATCCGATAGAGGACCAGGGCGGCGGTGGCGGCGGTGGCGTGGAGACTGGCCGCCGCTGCGCCGGGCTGCCTGCGACGTGCGGGCCCAAGGAAGACGAGAGCTGCTGCGCGAGCGAGCTGGTCGTGGGGGGTACGTTCAACCGGAGCAACGACCCGGCCTTCTCGGCCACGGTGAGCGACTTCCAGCTGGACCGGTTCGAGGTCACGCTGGGGCGGTTCCGGGCGTTCGTGGACGCGTATCCCGGGAGCCGGCCGGCGCCGGGCGCCGGCGAGCACCCGCTCGTCGCGGGGAGCGGGTGGGATGCGGAGTGGGAAGATCGGCTGCCGCCGGACCGCGCGGAGCTCCTGAAAGGGCTGTTCTGCGATTCGGAGGAGACGGCGTGGGCGTGGACGGATGAGCCCGGCGCCAACGAGCGCCTGCCGATGAACTGCGTGAGCTGGTACATGGCGTTTGCGTTCTGCGCGTGGGACGGCGGCCGGCTGCCGACCGAGGCGGAGCTGGGGTACGCGGCGGCCGGCGGCGCCGAGCAGCGTCCGTATCCGTGGTCCACCTCGACGGACGATGAGACGCTCGATCGGGACCACGCGGTGTATGCATGCAATGGCAGCGACGCGGCGGGGTGCGTGATCGAGGACCTCCTGCCGGTCGGGTCCAAGTCACCGCAGGGAGACGGGCTGTTCAAGCAAGCGGATCTGGCGGGGGGCATGTGGGAGTGGACGCTGGATTATCACGGAGATTACCCGCCCGAGTGCGTGGACTGCGCCGTCACGACGGGCGGCACGGAGCGGGCGATGCGCGGCGGCGGCTGGCGCAGCGCCGCGGAGGCGCTGCACCTCGCCACCCGCGACCACCGCACCCCGACGACCCGCGCGGCCGGCATCGGGGCCCGGTGCGCGCGCGAGCCGTGAGCGAGGCCCGCCTCGCCCGTGGTGGATCCTGGCAGGCCTCCGACGGAGGCGGCGCGGCGCGCCCTGGCGCGACGCGCGCGCCCCGTCGGCGGCTCTACCGCTTCGCGAAGCGGAAGCGGGCCCGCACCGTGGCTGTCACCTCGATCTCTCCGGGCTCGATCGGGAACGTGGTCGAACGCGGGCCGATGCGACTGGCCGCCATCTGCCAGGCGCGCCCGCCGTCGTCCTCGCCCGCGCTCGACACGGATCGCCACCCGACGAGCTTGATCTTGGCCGCCTCGGCGATCGCGCCGGCGTTGCGCTCGGCGTCCACGATCGAGGCCTTGAGCGCCGCTCGGTAGGCCTCCTGCGGCGCGCTCAGGAAAAAGCGGATCCCGCTGGTCTGGTTGGCGCCCGCGGACAGCGCCGCTTCGAGGATCCTCGAGCTCTCGACGCGGAGCACGTCGAGCGGCGCCCCCTCGAGGATCACCGAGACCGTGCTCGTCGCTTCGTATCCGATGATCCGCGGCGGAGCGAGGCGGTCCCGCTCCGTTTCGCCCTCCGGGATCGGGCTCACCGAGACACCCACGTTCCTGACCTGGAGCGACGGAATCTGGAGCCCCTCCAGCGCGCTCACGATCGCTCGTGTCCTGGCCGCGGCCTCCTCGCGCGCGGCCTCCAGGCTCTCGCCGCGGATCTCCACGGACACGTTCGTGCGGAGCGAGTCGGGCGGAAGCGACACGGTGCCGGACCCCTCGACCTCCACGACCTGCAGATCCGTAGACTTTACCATGCTGTTCATCCCGCCCCCTCCGTGAGGAGAACCTAAGGCCGGGAGGCGCGCTCAGGGAGGCTCGACGCGCCGCCGCGGCGACGAGGCAGGCGGGACAAAGGGACACGCGTGGAATCCGGGACGAGGGCGCGGCGCGCGGGTGCGCGCACTCCGGCGTCGCCCGATGACGTCACATCCACATCCGCGCCACGACGCCGTAGGTGCCGGGCCCCGGGGACATGCCCACGTCGCCGCCGCCGAGGAGGACCTGGTCGTCGGAGACGACCTCCACGGTGTGCAGCTGCCCGAACTCGCCGAGATCGACCGGGAGCACGCCGCCCTCGCCGAACGCCGGATCGAGCGCGCCGTCGCACGTGTACCGCACGAGCAGCGGCGTTGTCGTGCCGCCCTCGCCGCGCTCGCCGCCGTTGCCCGCGACGAGGACGGCGCCGCCCGGGAGCAGGGCCATGTCCTCGGCCACGTCGTCGCCGCCGGTCGTCGGCCACGCGGCCACGCCCCCGTCGCCGAACGCGAGGTCGGGCGCGCCGTTCGGGTGGAAGCGGCGGACCTGGAAGTCGCGCGCCCCCTCGGCCCCCGCGTCGCCGGCCACCACGATGCCGCCGCCCGGCGACAGCGCGAGCGCGACCGCGCGCTCGTCGATCCCGGGATCGCCGGCGACGATCGCGCCCCCGCGGCCGAAGGAGCGATCGAGCGCGCCGTCGCCGCGCAGGCGGATCACGATCATGTCGCGCTGGCCGCCCCGCTCGACCGCGCCGGCCACGACGACGCGGCCGCGGTCATCGAGCGCGACCGCCTCGGCCACCGACGCGGCGCCCAGCGAGACGGTCCTGTAGCCGCGCGGGCTCGCGAACGAGGTGTCGCGGGCGCCGTCCGCGGTGGCGCGCGCGATCAGCAGGCGCCCGTCGCGCTGGCCCACGGCCACGATGCCGTCGTCCGGAGCGACGAGGCCGCCCCGGATCTCCTCGTCCCCGCCGAGGTCGAGCAGGCTCTTGCCGCCGTCGCCGAAGCCGGGGTCGAGCGAGCCGTCCTCCGCGTAGCGCGCCAGCGCCACGTCCGCCGAGGCGTCCCGGAACCGGTCGCGCCAGCCGATGGCGACGATCTCGCCGCCCTGCTGGCGGCCGGTGGCGGCCAGATAGGCCATATCGCCGGTCGAGTTGGCCCAGCCCGTGGTCACCATGCCGTCGCCGAAGGTGGAATCCGGCGCGCCGGCCCCGGTCAGCCGGACGACGCGGAACCTGATCCCGCCGAGACCGCCCTGGCCCCAGCCGGCCGCGATGATCCGATCGTCGGCGACGTCGACATCGAAGAAGCCGCCGTCGTCGTCGGCGCCGAAGCGCACCCGCGCGATCCCGGTCCCCGCCTCCCCGAACGCGGGATCGAGCTGCCCTGCGAGCGGGCCAGGCTCGTCGCCCGCGCAGCCGCAGCGTTCGCCGCCGCGCGCGGGCGCCGCCCTGTCGGGCGGGGCGCTGTCGGCGGGGGCTCCGGCGAGGAGGTGGCTCGGGACGAGCAACGTGAGCAGTGCATAGAGCGTCTTCATGAGAGGAACTGTTGGGCGCGCGAAGGGGGGTGTCAAAGGGGCAGCCATGCTGACGTCGCGGCGTCGTCGCGGGCGCCGGAGATCTCGTCTCCAACGCCTCGGACACATCCCGCGCGGTCCGCCGCGCCCGCCTCCTCCGGCGGGGCGGGCCGAGGCGCGCCCCGCGAGGCGGCCCTGCGGCGGGGGTGAGATCCACGCCCTGGGATCACTCCGCCGACAGCTTGGCTCGTGCGACCCTCTGCACGTACGGGTCCACGTCCTCGCTGGCATCGCGCCAGTGTCGCAAGGAGCTTCCCGGGTCGAGCGTGGCCAGCGCCGTGAACGCCTCCGCGCGGATCCTGGCGTCGGAGTGCCCTTGCGCCAATTTCTCCAGGACGTTGATGGTCGCCCCGTCGCCCACCATGGAGGCGAGCCTGCACAGGAAGACGAAAGGGCTGTAGTCGAGCCGCTCGACCGACGAGGAGATCACCCCTCGCTCCACGTCGAACCAGTACTGCTTGGTCGACTGCACGGCCTCCGGATCGGCGACGAGCAGGTTGATCGATATCGAAAAATCGTCCGGCGGCAGCTGCGTGTGGATATCGCGGTTCGCCCGGTAGAACATCACCTTCCCGTTGGTCAGCCGCGTCCTCTCCAGGAACCGTATGTCCACCTGCTCACCCTCGAACCCGACGGTCCGCTCCGGATCGTACTCGTAGATGTCTGTCTCGTATCCAGGGCCCCAGTAACCAACGGTGAGAAAATCGGCGTTGTGGTCGTGCGGCATCTGGTACGCGAAGAGGCTCCTCTCCCAGTCGGCGGGCGCGTCGGCGACGCAGCGCGGCCACATGTTGGCCCGGAGCCGGAACCCGGGGCCGCCGCCCAGATCGACGATCTGCTGCGAGAAATTGCTCGACTGCTGATAGGCGTCGAGCGGCTGCGCCTCGCAGATCTGGCGGTTCACGAGCTCGATGAGGAAAGATTTGTTGTTCGACAACATCCTGAGGTAGCGGGCCGCGTCGTCCATGCGTTCCCGGCGCGAGATGCCCTTGATCCCGCTCAGGAGGCGGACGCACTCGGGCAGGTCGATCACATCATTCGTATTCGCGTCGATGGTCAAGGTCATGGCGTGCTCCAGATGTCATCCCAGGCGAGCGAGGGCCTTCTTCGCTGCTCCTCGGATTCGCGGGTGCGGGTCGTCGACGGCCCCGGCCAGGCGCGCTCGACCGGCCTCGGCGTCGACGGCGAAGAGGGCCTGCAGCGCGGACCAGCGGACGAAATGACTCTTGTACTCGGAGATCCGAAGGAGGCTCTCGATGTTCCCCCGCCCCGTGACCTCCCCGAGGAGCTTGGTGGTGTAAAAGAGCCTGTAGGCCGAGCTGTTCGGGCAGATCGCCTGCATGGGCATGAGGGTGCCCGGGTCGTACTGCCACGCGAAATCGAGGAACGGCTTGGACTGGAGCAGGACCAGCGGGATCGGCCTGTCGACGGACCGCAGCCGGAAGACCTCCCACCCGGCCGAGACCTCCGAGACGTCCATCGATCGAAGCACCTGGTCCGGCTGCTTCTCGAGCATGGCCCGACCATCGAAGACGTCGTTCCGATACGGCTCGACGTGCCTGTATCGCTCCAGCACCAAGCGGGCGTCGTCGGACGCGGACGCGAAGCCCATCAACACGTGGGATGGATAGCTGAGCAGCTTGTCGTCATCGACGGTGGGATCGAGCAGCAGAATGTCGATCTGCACCCCGCTCGGCAGCATGACGCGGGCGGAGGAGCCGGTCGCGGCCTGGATCACCTCCCCCTGCCCTGAGAGGCAGTATCCGAGCTGAGTGCTCAGCAGGTCCGCGAGGAAACCCGAACCGAGGAGCCGCTCGAAATGAGGTCGGCACGTCCAGAAGGTCGACGGTTCCTCGATGTTGTACGTCTCTGAGATCGCAGCGGAGAAGCTGCTCAACTGGGCCGTGATCATGGTGCTCCTGCTCCCTCTTGGTCGAAGCGCGCGCCGCTGCCCACGTCGTCGTCGACGCGAGCAACGGCGCGGCGGACTCAGGATCCTCCGATCACTGCGGATCCGGGGACTTGCGATAGCTGGTGTCGACGGCGCCGGGGACCATGGCCAGCACGATCACCACGAGCAGGACGCCGCCTGCGACGCTGGTGACGGGGGTGGCCGGGGCGATGGGCTCATCGAGGTCCTCCAAGACGAACTGCTGGGCGCGGACGGGGGACGAGGACACGGCTTCGCTGGTGTGCATGATATAGGCTCCTTGTCTCAAACGAGAAAGCGTGAATGATTCTCAACCGCTCGCAGACCACCCCCGCGGTTCAGGGGAGCACTTCTATCGATGCGAGCCCGTGCTTGCGCGCGTCGAGGAGCAGCTCCTCGTCGGTCATCTGGACGCCGTGAAAATCGTGATATTCCTTGGCCAGCTTGATGAACGCGTGATTCGCCGACGGAGACGCGCCCGCCGCGGCGTTCCTCGCCCCGCTGGAGGCGTGGCGGACGTTCGGGCTCAGCGTCGGATCGGCGCTCGCGAGCTCGGCCAGCCGCTGGTTCAGGTTGTTCATGGCCTCGATATAGACAGCGGCGAGCCTGAGGACCTCGGCGTCCTTCACGGCACGCTCGGACACGAATTTGTACCACTCTCGCGAACGCTGAAGAGGGTGAACGATGGTCATGTACATGCCTCCTTGATGGTTCAGTCAGAGCCAATGGCCCTTCTACGTCACGAGCGCGCCAACGGCGATGTCGGCAAACCGGCCGACATGAATCGTGGAATTGGAATCGACGTCGCTTGCGATGCCGCCGTTCGCTGCCGCTCCATGGCGGGCAGCACGAGCTCGCAAGCGCCGGGCCAGCCCGGCCGAGAGGAGCACGTCGGGATCGGGGGAGCCGATCGTGGCGGGGTCTCTTCGCCGGCGGGCAGCAGGGAACGGCGAAGCGATGACGGAGCTCGAGCCGGCGCGCCCAGCGCGGCGATGCCGCGGGCGACCCGGACCCGCTGAGCCGGCAACAACTTGCCGGCAAGGTGTTGCCCGCGCCGGGCGGCAACGGCTTGCCGGCGAGGCGGCGCCCTCGCGGAGGCGGACGCTGGAGGGCCGGGAGGTGCGCCCCGCTGGAGGCTTCCGCCGAGCGAGATGTGGTCGGGCGCCGTGGCCCCGCGCCCTGCTCGGCGTCGACGGTGCAGGCGAAGGCCCTGGGCACGCGACCGCCCGAAATCACGCCGCTGCCCACCAGGCTGGCGGCCAGGACTTCGCCGATAGGTCCTCGGGCGGTCCGGTCGCGCGCGCTGCACCGCCGCGGCGGGCCGCGGCTGCCGTCCGATGGCCGTCCGGACGCCCGCGACCACGGCGCGGGCGGCGAGTTCATCGGTCTCCGCTGGTCGAGGTCTTCCTCCGAGACGGAGAGCAAGGAGCCCCGGCGCACGGAGGGCCTCTCCGTCAAGGCGTGGACAATTCGACTTGTCCTGCCCTGACCCTGCGGTACGCTGCCCGCCATGATCCGCGAGATCATGTTCCACCCCGAGTTCACGACGCCGTTCGGGCTCCAGCCATCGGGCCCGATCGGGGACCTGGGACGGATCGTCATCCTCGTCGGCCAGAACGGCGCAGGGAAGAGCCGCTATTTGCAGCTCGTCAAGGATCTGTTGGAGACCGCGCCGCGGGCCACCCAGGAGCATGCCACGTTGACGGAAGACCTCCTCCGGCTCAAGGCACAGCTCGCCGCGACCGGCGCTGATGCGCTGCCACCGGAGCGACACGTTCAAGCGACGCGGGAGGTGGAAACGAAGACGCAGCGGCTCGCCTTCGTGACTCGGCTGTTGGCGTCAGGAGGGGTCCTCGTCGATGGCCCCGGCGGCCTCGTCCCGCCGACGGCGCAGGATATCGGTATCGACCTGACGATTCGCCCCTTCGGCCTGAGCGAGGCAGGCGCATCGCGTCGCGACCCGCTCCGTGAGGCATACAGGTCTGCGCCGGACATCCTCGAGAGGGCAGCGCGCGCCCTGTTCAATGCAGAGCACCCCGCGCTCGCGAAGACGCCGGAGGTCGTGGAGTCTGCCCGCGAAGCCGCGCGCCTCAATGATATCCTCGCGGCGTTGCTCGACAAACAAATTCAACCCGATGTGGACATGACGAGCGGAGCAGTTCATGCTCGGCTCGGAGAGCGCCGCTTCGACACCGTCGAGCTCTCCTCCGGTGAGCGGGTCCTGTTGACCTGGGCCGTGACGCTGCACCGGGAGGCGTCGCAGCTCCGCGACGCCGTTCTGTTCATCGACGAGCCCGAGGTACACCTCCATCCTGCGGTGAGCATACGGCTCCTATCTCGCCTCTTCGACGATAAGGTCCTCGGTCCGCGCGGACAGGTATGGATAGCAACGCACTCACCGGTCGTGCTCCTGGCCGCGGACGCGGCGCGAGTGCTGCTGGTGGAGCAGGGAGCCCTGCGCTGGAGTGACGTGTCCTCCCCGCAGGTCCTGGACGGCTTTTTCCCCGGGACTCCTCCGCAAGTGCGCTTCGCCCCCCGGCTCCCCGTGGGGGGCTCCGATTTTCGGAAGCTCCGCAGGGACCATCTGCGCTACGTGGACAAGACGGCGTTCATCGCCGAGGTACTCCAGAATCCGGCCGAGGTGCTGCTCTTCTCACGCCCGCGGCGCTTCGGCAAGACCTTGAACCAGTCGATGCTACGCTACTTCCTCGAGAAGACGGGCGAGGAGAGGAGCGACCTATTCAAAGGTCTTTCAATCTGGGATGACAAGGAGTCTCGACAGCACTTTCAGGGATATCCGGTCGTCGCTTTGACGTTCAAGGACGTGAAAGCGAGCACCTGGACGGAGTGCCGAAACACCATGGCGTTGACCATCGCCAATGCTTTCGAAGAGCATGGCTACGCGGTCAAGACGGGTGCGCTCTCGGAGCGGGAGGCTGAGCGCTTCGACGCGATCATGAGGAATACAGCAGACAACGCCCAGCTCCGAGACGCCCTGCGGCTCCTCTCGGAAGCTCTCTCGCGCCAGCACCACCAACGCGTCGTCATCCTGATAGACGAATACGACACGCCGATCCACAGCGCCTACCTTCACGGATATTACGACGAGGCCATCGAGTTCTTTCGTAACTTCCTCTCCGGGGGACTCAAGGACAACCCGAACCTGTTCAAGGGGGTGCTGACCGGCGTGCTGCGGGTGGCCAAGGAAAGCCTGTTCTCCGGGCTGAATAACGTCGTGAGCTACTCCCTGCTGAGGCCGGAGTTCGCCAGTCACTTCGGCTTCACCGAAGAGGAGGTGATGCAGCTCTTGAGAGAGAGCGGGGAGGATAATCGGCAGGAGGAGCTACGAGCCTGGTACGACGGCTACCGCTTCGGTGACGATACGATCTATAACCCGTGGTCCGTCGCGAATTATTTGAACCAGCGGGACCGCATGCCGCGGCCGTACTGGACAGATACGAGCGACAACGAGCTCCTCAAGCGGCTCCTCTTCCACGAAGGAGCCGGTCTCCACGGCGAGTTGCAAGCGCTCCTGCGGGGCGAGCCGATTCACACGATTATCGCTGAGGACGTGGTCCTCCGGAATATCGGAGACAGGCATGACGCAGTCTGGAGCCTCCTGCTCTTCTCGGGATACTTGACGCCCTCTTCCAAGCCCAGCGCCGACGCCGAACAAAGGCTCGACGTGAAGATCCCCAACAAGGAGATCCTCCATGCGTTCGAGAGACTGGCGCGGGAGAACCTGGCGGAGCGCATGGGCGGCGAGGAGGAGGTCAGGAAGCTGACCCAGGCGCTCATGGACGGGGACGCGCGGACATTCGAAGGCCTTTTGGAACGATACCTGCTCAACTGCATGTCGTCGCAGAGCGCGGCGGGAAGAGCTCCGGAGATGTTTTACGAGGGCTTCCTCTTGGGGCTCCTCGTGCGTCTGCGCGCGGACCACCACGTGGAATCCCAGCCAAACGCAGGGCTGGGGAGGGCCGACATCCTGATTACCCCCAGGAGCTCGGGGCGACCGGGCGTGGTGCTGGAGCTGAAGACCCTCAAGGATGGGGGCGACGTCGAGCCGGCGCTCGACGCGGGTCTGCAGCAAATCGAGGACCGGCGATATACCGCGAAGCTGGAGGAGCGCGGGGCCCATCCTATCCACGCATACAGCGCGGTCTTCGATCGCCAGCGCGTCTGGGTGCGGAAGCGAACCATGTGATGGTCGTGAGGCGCTCGTCGTGGTAGCCCGTGTCGAGCGGCGAGCGCGGCGAGCTACGGCTCACCGGGCGAAGCGGCGGATCGCGTGCCGGATCTGCTCGGCCGTCATCGGATCCGTGGACAGCGCGCTGTGCAGCACCAGGCCTTCGATCAGCGCGTCGAGCTCCCGCGCGGTCACCGGATCGAAGTGGAGCTCCAGCGCGCGTCGGCTCCGCAGCATCCAGGCCTGGGTGACGGCGCGCAGCGCGGGCCGCCGGGCGGCGGCGACGTAGAGCTCGACGCTGAGCACGAGGTCGCGCGGCGAGCCGAGCAGGTCCGCCGTGAGGTGCTCGACGAGGAGCTCGACCGCGGCCTCGCGGCCGCAGGCGGCGCGCATCCGCGCCTCGAAGCGGGACGCCGCGGCCTCCGCGTGCCGGGTGAACGCCGCGGCGAGGAGCTCGTCGATCGACGCGAAATGGTACGTGGTCGAGCCGAGCGGCACGTCCGCGGCCCGCGCGATGGAGCGATGCGAGGCGCCCGCGACCCCTTGCTCGGCGATGACGTCGAGCGCCGTCGCCACCAGCCGATCCCTGCGCCCCGGGTCGTGGCGGCGCGCCCTCCGGGCCGGCGCGGCGCGCCTCGCGCTGGCTCTGGCCATCGCGCCCCCGTCACCCTCGCGCGTCGCCCGCCGCCGGCGCGGCCCCGGCCGAGGCGCCGTCGAGCGTGCGGATCACGCGCGCGGGGTTGCCCACCGCGACGACGTTGGCCGGCAGATCGCGCGTCACGACGGCGCCGGCGCCCACCACGGTGTTGTCCCCGATCGTCACCCCGGGCAGCACGATCGCGCCGCCGCCGAGCCACACGTTGTTCCCGATCGCGATCGGCTTGGCGGCCTCCCACTTCTGACGCCGCGGCTCGGGGTCCAGCGGGTGGGTCGGCGTGAGCAGCTGCACGTTGGGCCCGATCTGCACGTCGTCGCCGATGGTGATCGGCGCGACGTCGAGCGCCACCAGCCCGAAGTTCGCGAAGCAGCGCGCCCCGATGGTGATGTGCGCGCCGTAATCCACATAGAACGGCGGGCGGATCTCCGTGCCCTCGCCGATCGCGCCGAGCAGCTGCTCCAGCAGCCGGCGGCGCAGCGGGCGCTGGCGCGCCGAGGTCGCGTTGTAGGCCGCCATCAGATCCAGCGCCGCGGCGCTCAGCTCCGCGAGCTCGGGATCGCCCATGTAGAGGTCGCCCGCGAGCATCCGCTCGCGCATGGATCGCGTGTCGACGGGGGTCGTCATATGGACGAGTGTACGCATCATCGGAACGAGTGTCCACATCGCCGGCCGGAAGAGCTACGCCGGCGCCTCGAGCGCCGCCGAGCCACCGTGGCCCGCGCCCTCGGACCTGTTCCGCATGTCAGACATCCCGCCAGAGAAAACGGCCGATGGCGAGCGGTCGCCGGAAACAGCAGCGATTCACATGGTTTCCGTCTGCTTCGCCGCCGAGGGCGGCTCCGGTGTGGCCCAACGGGGCGCCCTGCGCCGCCGCATCGCCCGCGGTGAAGGGTTCGTGGCATCACCGGTCCCACCGTACGGTCACGCTGCACGCGCTGGTTGACATAGAGAACCTTACATGACCGCCTCGGTCGGCGGGATCGCACCGGCGCAGGACGGACGGACGCGCGCGGCCGAGGCGCGGGCCATGGGCAGCTTTGGCCACGGCGGGATCCGCTCGGAGAAGACGGCGAGAGCCCGCGGAGCCATTGCGGGGCGACGACGTGTGGCGCGGCTCCCGTCCCGAGAGGGCGGAGGCACAGAGCGCTGCCTCGGGCTCGTCGTCCTCCTCGACGTCGTGCTCGATCTCGAGATGCTCGTGCCGCCGGAGGTAACGGAGCATCCGCCCGACGGCGTGCTCTATGACCTGACCGACCTCGCGCGTTCGCAGGTGAGCGAGTTCGTTCCACACGAGCTCGGTGCCGTCTTCGCTCTCCCAGGAGGGCGACTTGAACCTGGACAAGAAGATGCTGGACGCCTTGGCCGCGGCGGCGCTGAACGCGGACGACCCGCTCGACGTCTGCGAGGCCGTCAAGGAGGAGATGCGGGAGCGCGTGCTGCGCGCAGCCCTCGAGGCGGAGGGCTGGAACCTGAACGCGGCCGCACGGCGGCTGAAGCGCTCGACGAGCACCGTGCAGTACGCGCTCGAACACACCTACACGGTCCTGAACGTGGAGCGCCTGGGCCGGCTCGCCAGCGCCAACGAGCAGGCCTCGCCGGCTGCGGCAGCGGCGCCCAAGGCGGACGCCTCGCGCCGGACGGTCCTTCGCGGCAAACGCGAGATGAACAACACCGGCGGCTTCGAGCGTAGCCGAGCGCCCGGCTCGACTCGCTACCGAACGCGACCAAGGGATCAGGAGAAAAAGCAAGCGCTATCGACTTGTGCGGTTCTCCGCGGACACCATCCATACGGCCATAGAGCGCGGTGGCGGACCGGCCAAATCCAAAGACATTGTGAGCTTGGACTCGCACATAATCACTCATGATGATGGGTCTGAGTGGTCGTACGATAACCTGGACGAGTTTTTTTTGCTGACTACCGGCGGTACTCCTGGGACTCACGTCTGGTTATCAGGTGTGAGCGATGCGAGCTCATTGTTCAGGTAGTCGGCGGTTCGTCTTCGCTGGTAGAGGTGACCGCTGATGCTAGGCCGCAGATCGAGCAGGTTTCCGATGTGTTCGAGCGAGGTCTGGCAACTGCTCACACATACAAATCCGAGGAACTGGACCCGGAGCTCGTTGTTTTTTGTTGGACATGGCCGCAGTGGACAGTGGCGGGACCTGAAAGATCATCTCGTCGACAAGCACGACATTAAGGTGAGGGCCTATGAGACCGGGCCAGAGCGGGCCACGTCATAAGGGACATTCTTGAAGAGATGGTTCAAGAGGCTTCGTTTGCTCTTCTCGTGCTCACCGCAGAAGACGAGACAGCGGATGGCACGTTCAGAGCTCAACAGAACGTCGTTCACGAGACCGGCCTTTTCCAGGGTCGGCTCGGCTTCAGTAGGGCGATAGTTCTGGTGGAAGACAGTGTCGAGGTTTTCTCGAATCTCGACGGTGTTCAGCAAATCAGGTACTCCAAAGGTAACATCGGAGAGACCTTTGGAGATGTTCTAGCAACGACCCGTCGTGAGTTCAGATAGGCGAGGGAGCCGCGCCGGCGTCACATCAGCAGCGCGCGCGCCTGGTCGTCGATAACGGCGATGCCGACCTCGCGGCGCTGGCGCCCATCGGTGGCGTCGACCTCCGCGCGAGCCGGGGCGGCGGGGGCCGAACGTGCGGCACGCAGGGGCTCGTCGGCGCGGTGGACCCAGTCGCGGATCGCCGTCGCGAAGGCCCATGGCCGTCCGGTGCCGACGCCTTGGACCGGTAGCGGGTCGTCGGCGTCCCGGGCGAGCCGGCGGGCCGTCGTGGGGTCGCAGCCCTCGAGGCGCGCGCAGATGGCCTCCCAGCCCTCGAGGCGCTCGCCGATGCCGCGGCGGCGGTCCTGCCAGTCGTCGAGGTAGCCCGACCAGGCCCAGCGGAGCGTGGTGCCGCGCCGGCGACGGACCGGGAGCGGATCGACCCGCAGCGCCGCCCAGGTCTGCGCCGTGGGGGTGGAGACGCCGAGGTGCGCCGCGATGGCCGCCCAGCCCCAGAGGCGTTCGCCGCGGCCGCGGGGCGGGGGTGGCGCGGGGCGGCGCCGCCGCTCCAGGCCGGCGAGGAGGTAGCGCCGCCGGCGCCGGCCCGACCTTCAAACGTCAACGGGAAGCCGCGTCGTTGCACGCAAGCGGGCGGAGCTCGGCGGACGCCGCGCCTCCGGAAGAACATTTCGTGGGTCCCGAGGTAAGGATCGGCGCCGTCATCGCGTCGTAACCTGTGAGCCTGGAGCAACCCGCTCCTCCTAGCCACGACGAAGACATGAATGACACAAACATCACCGTCGCCCACGGATCGCCGCGTATCTCCGACCGCATCGACAACGTCCTCCGCGAGCACGGATCGAAGTCGTCCGGGAGCCTCCACGCCATTGCCTCGGCGGCCGGCCGGTGCGGGCTCGTCGCCATTCTGCTCGGCTTCGGCTTCTACAAATTCACCGCCGTCGAGGCGGAGGCCATCGCTCCTCTTGTGTCGAACAGCCCCTTCATGGGCTGGCTCTACGCCGTCGGCTCCGTACGGACGGTGTCGGCCGGGGTCGGGGTCACGGAGATCCTGGTCGCCGCGCTCCTCGCGGTGCACCGCTGGTGGCCGAAGGCGGCGCTGCTCGGCGGCCTCGCCGGCATGCTCATGTTCCTGACGACCCTGAGCTTCGCCTTCACGACGCCGGCCGCGACGAGCGATCCGGAGCTGCTCGGGTTCCTCGTGAAGGACCTCTTCCTGTTCGCGGCGAGCGCCCACGCGGCGAGCGCTTCGCTCCGCGCCGCCGCGTACCGGGCTCGCACGGGCGTGACCAAGTGACCCTTACCGGAGCGCGAGCGCGAGCAATCAGGTTTTGCGGAAGACGAGCGACCAGGCGGGGAGACATTCAAGCTGGAGGTTATCGCATGAGGAAAATGACCTTTATCTCGAGCATCACGGGGCTTGGCATGGTTCTCGCGGGATGCGTCTCGCACAAGGAAGCATCCTCGGACAGGATCAAGGCTGAGCGGGAAGCGGCGCAGGTCGTCTTCGACGAGCAAGGTGAGGCGTTGCTTCCCAAGGGCTATCGCTCATGGGTGCACGTGTCGACGTCGTGGTTACCGATCACCACGTCACTCCTTGACGGCATGATCACGAAGACGCCTGAGCTCTTTAATACCTACGTCGAGCCGATCGCCTTCAAGACCTATGTGAAAACTGGCGAATGGCCGGATGGGACTCTTTTTGCCAAAGAATTCACGACGACCCGCGTGGACGCCGAGTGCGATGGCCCGCCCGCATATGTCTGCAAGCGATGGTACGGCAAGGCAATCTTCCAGAGCGCTTACACCGGTGTCGCCATCATGCTCAAAGACAAGAAGCGATTTCCGAACGAGCCGGGCAACTGGGCCTATTTCAGCTTCGGGCACCAGCCTCCGCCCTATCAACCCGCTTCGCCGCCGCGGGCTCGCGAGCGATGCGCCCAGTGCCACATCGACAGAGCGGGGCCCAAGCTCGACTATGTGTTCTCCGTCGAGCGCATCGGGCTGGATCGTGCAGGAGACTCCAGGAGAGACATTCTAGAAGCTTCGCTTCCGGATTGATCGGAACGACGACGCGGCGCCAGTCGGCGCATCCCGCGGGGTTTGGCAGCCGAGGGCCTGACGCGGTCGCTCGTGGTTGTAGAAGGCATCATGGTGAGCTCAGGGCCGCCGCTCAACCTGCTCCGCGTCGATGTTGCTCGATCGACATAGTCCTCGACACCTCGCTGCCTGGTGCCGCTATGCTACGCCGGTGGACTCCGGTACCCCCACGACGGTCTCGGTGGACGGCGCAGAGCCCGCGCCAACACCCACTGACGGAACGACGCTCTCTGCCGCGGCGGCGGAGGCGCTCGCCGAGCACCCGGCTCGCGCTCGATATGTCGGCGCGCGAGAACGCAGAGCGCGAGCGCGCAGCGTTGCAGGAGGAGATCATCCGGGTGCAGCACAGCCGGCTAGCGGAGCTGTCCACGCCGATGATCTCGACCACCGAGCAGGTGATGGTCATGTCTCTCATCGGGACCATGGATGAGCAGCGTGCCAGGCACGTGCTTGAATCTGCGCTCTCTGGCGCCGAGGCGCATGGTGCGCGTGCCGCCTCCGTGCCAGCATGCAGGAGCCTCTTCGCCGCTCGTTTTCCCACCGCTCCCCGCGGCGTCCGCAGTTCCGCCATGGCGTCGCCATGCAGCATCGCGGCGAGAGGGTCGTCGCCTGCGCACGCCGCCGCGCTTGCCTCCCGGCACAGGCCTGCTGCTTGCCGGCATCACTTTCCGGATGCCTCCGGGGCGCTTCGGCACGCAACCACCGCGCGCGGGCGGTCCCAGTAGAGCCTGCGGGCACTGGCGAGCGGCAAGGCTCCGGCAGCGAGTCGACGCGAGCGGCGGGCTCGACGTTCGGCCCAAGCTTGCTCACCCCTCCGGTGCCACCGGCAGCCCGAGCAGCTGACCGATCGCCTCGTGCACGACCCGGGCTGCCTCCGCGTCCCCGAGGGCGACGGCTCGGCTCAGGGTGGCGGCGAGCGACGCAATCACGGCGGCTCGAGGCGTGGGATCGACCATCGCGAGCTCTCCGGGCCCAGGGCTCGGCGATTGGGCCCGGGTTGGGTCCATGCCTGCCGGCGCGAGCACACCGTGGTAGCGCACCAGCGGATGGCGCGGCGGCGGCACAAGCGCGGCGAGCCTCGCGAAAAACACAATCGGCGTCATCACCCGATGCGTTCCTTTTCGCCGCGGGTATTTCACCTGATAGGCCACCCGACCGTCGCGGAGGATGCTGAGCCGCTCCAAAGCGAAGCAGGGACGCGCGCAATACCGGACGAGCCGCTCGCGCCCCTCGTCGTCGTAGCCCTCGATGCGCACCGCCGCCTCGACGTTGAAACCATCGAGCTCCACCGTGAGCGGATAGGACAAGCAAACGCGTTCCGCAAAGTCAAGATTCTCGGAGCCGTTCCTGGCTCGTGCAGTCCGACTGTACGAGCTTATCGACAGAACGGGCCTTATGCGATCAGACAGGCCTTCCACTCGTGAAACGCCTGCGATTACCGCGACGTCGCACCAAGCGGAAGGCATCCTACCGTATAGCTGTACACTACTGAGCTCGTCCAAACGGCCGCCGTCGCGGTTCGCGGCGCGTCGTGATGGCCGGCGCACGCACCTCAGGGCAGACCTCCCCCCGGCCACGTCGTCGAGCAGCGTCCCTCCCCTTTCAGTTTCGTCACGCGGGGTCCGCCGGGTACCGCGCGCGGCACTCCAGCGGCTCGGCGAACAGACCGAGGTGGCTCAAGATCTTCCTCGCCGTCGCCTTGTCCGTGATCGCGGCCATGAGTCGCATCCGCCCGCTGCATCGCGGGCACGCGAGAACATCTACTGCGTAAGTCCGCCGCAAAAGCTTCGCCCATTCGACGCGAGGCGACGTCGCCAGAAGGAGCCCATCCAGCAGCCGATCAAGATGCCGGACCGAGATCCCCTCCGACACGAATCCAACATCAGCCCACGGCAGTACAGCGCCCAGCGCAGTCGACACCCGCTCGCGCTCGACCGCGCCATGCACCATCGTCAGCAGCGCCCCAACCGCCACGTCCCGAGCGCCTCGCTCCGACACTGCCGACGGCGCCGCCTCGCTTCGCTCGTCTCGTCTGCGCGACGGCGTCTCCATGCCTCTCGCCGGCCCCTTCGGCGCCTGCCTCGCCGGCAAGGGCGTGATCGTCGTCGTCTTCTTCTTGTCATCGCTGCCCGCGCTATCAGCTCCGGCGCGCTGCTCGCCCTTACGCGCCTTCCCCGTCGCCTTCGGCACCGCGAGGCTGCGTTGCTTCGCATGCGGCGCGAGCACACCGTGGTAGCGCACCAGCGGATGGCGCGGAGGCGGCACGCGCACCATGCGCCTCGGCGCCAGAGCGCAGATTCAAGCACGAGCCTGACACGGCTCATCCATGGTCCCGATGAGAGGCATGACCATCACCTGCTTGGTGATCGGGAACATCGGCGTAGACAGCTCCGCTAGCCGGCTCTGCTGCACCCGGATGATCTCCTCCTGCAACGCTGCGCGCTCGCGCTCTCGCGTTCTCGCGCGCCGACATATCGAGCGCGAGGCGGGTGCTCGGCGAGCGCCTCCGCCGCCGCGGCAGCGAGCGTCGCGGCCCGCCGCCCCCCGGCCCGCCGCTCCGCCATGGCGCCGCCATGGGCGATAGCCCGGCGGGTTGTCGAAATTCGCGGCGAAAACGCGCCCTCACCGCGTGGCGTGCGGCGTGCGGTGTCGGCGCCGTGTGGCCAGCGCGGCTCGCACCACGGGCGTCGTCTACGAGCGCCGTCGCCCCGAGAAGACGACGCTCTACGAGATCGTGCGCGACAACGTGGAGACGCTGTACGGGGCCATCGACGACGGCGCCATCGCCGTCCGGATGCCCAAGCACGCGAAGAAGGAGCTCGAAGCCTGCCTCGACTTCGGGCTGCTCTGCCGCGGGTTCGCGCGGCTCCGGTGCGAGCGCTGCGAAGAGAGTCGGCTGGTGGCCTTCAGCTGCAAAGGACGCGGTTTCTGCCCGTCGTGTCTGGGCCGACGCATGTGTTCCACGGCGGCGAACCTGATCGAGGACATCCTGCCCGAGGTGGCGCACCGTCCGTGGGTGTTGACGTTTCCGTTTCCGTGGCGGCGCAGGCTCGCCCAGGACGGGGCGTTGTTCGGCGTGCTGACCCGCATCTTCGTCGAGAGCGTGGAGCGGTTCTACGAAGAGCGCGGTGCGCGCCGAGGCGCGTGCGGCGCGGTCAAGAGCGGCGCGGTGACCGTCGTGCAACGCACGTCCGGCGACATGCGGCTCAACCCGCGTCTGCATGTGGTCTTCCTCGACGGGGCTTATCACGAAGACGGCACCGAGCTCGTGTGGAACGAACTCGGTCACCTGCGAACGCGCGAGGTCGGTCAGGTCCTGGAGCACGCCGTCGGGCGGACGCTCCGAACCCTTCGGCGGCACGGGCATCTCGAGATCGAGCACGAGGTCGAGGAGGACGGCGAGCCCGAGGCAGCGCTCTGTGCCTCCGCCGTCTCGGGACGAGAGCCGCGCCACACGTCGTCGCCCCGCAATGGCTCCGGGGGCTCTCGCCGTCTTCGCCGAGCGCGCTCGCGTACGATAAGCCGCTGTGCGCTGCGCTCGATGGCTTCACCTTGCACGCAGCGACGCGCGCCGGTGCGCGCCATGCCGCGGCGAGGGAGGCGCTGCTGCGTTACGTGCTGCGACCCCCGATCGCAAAGGAGCGCGTCGAGCCGCAGCAGGACGGCCTGGTGCGGCTGTCGCTCAAGCGCGCCTTCGCTGACGGGACTGTCGCGGTGGACATGGATCCGCTCTCGCTCCTGTGCCGCCTCGCGGCCAGCGTCCCGCCGCCGCGCTTTCACACCGTCAAGTACGCTGGCGTGCTCGCCTCGGCAAGTCGCCCACGTTGGCGCGCAAGCGCATCGGACCGCGCCCTGCGAAGCCAGAAGAGCCTACGAAGGCGGACGAAGACGCCGCTTCGAAACGCAAGCGTGGCGGCTATCGGGCGGTCGACAAACCGCGCCGAGCTCTTGCGCCGCACATGTGCGATCGACGTCCTCGAGTGCCCAGCTTGCAAGGGGCGGATGAAGCTCGTCGCCATGGTGACCGAGCCAAGGAACATCGCCCGCTTCCTCTCCGCGCTCGGCGAGCCGACCGATGTTCCAGCACGCTCTCCCAACGCCCACGTTGCGCCCGCCGTACTGGGGGTTCGGGGCGCAGGGCGCCGCAGGCGACCCGGAGCCCCGAGCGTTGAAGAGCACCGTTCTGCGCCGCAAGGCGCCCGGTGACGCCGCATAGCGTCTCGCGACGCGCCTCCCGGGCCAGACCAACGCCCGGACGGACACGTGTGCCCACGGCACGCCGATGCGCCCCTAGCGCGCTCGGCGCCGCCCGGACCACGCTCTTTCGGCCCAGGACCGAGCCATCACGACGCTCGCGGTCCCACCCTTTCGGGTTGCTGCGCACCACTTCTTCGCGCTGCGATCCGGCTTCTTTTACCTACGCGCTCTTCTGCTTGGAAGCTTCGCGCCTGGCCCGCAATGGACGCGACTGGGCAACGTCGCGCTACGTCGAGTGGGTCGTGCTCATGAAGCGTTCGTTCGGCTTCGATGCGCTCCGCTGCCCGAGATGCGAACGGAGGATGCGCGTGCTTTCCACGATCACCGACTCAGCGGTGGTGCGCCGCATCCTCGATCATCTGAACTTGCCCTCGCAGCCCCGAACGGCAGCACCCGCGCGCGATCCAACGTGGGAACCGATGGCGTTCGGGTTCGACGCGGCGTAGGTGGGCACCCGGCCCGAGCCCGTCATGGCGAACGCACGTCGCGGTCGTCGAGCCAGAGCTGCACCCAATGCACGGCGCGCGGGCCCTGCGACGGGGCGAGCGGGTGTTTGATGCGCGATAGACGGCTCGCCCGGCGTCGTTCCCGCGGGGCTCGACACGGGCGAGAGCTCTATGGTTTCCTATCCGCCGCTCGGCGACGGCGAGCCCGCCTCCAGTCCCGCCTGGCGCACGCCTATTGTGAGGATCCATGCACCGAATTCGTGATCTCGAGGAGCGACCGCACGAGCGGGTCCTTGTCGTCCATGGCGCGCCACACCGAGCGGCCAAGGATGACGACGTTGAGGTCCCGAACCCGCTTGAACACCACTCCGGCAAGGAGCGTCGACGCGGCGCTCTCGGGACACAAGCTGAGACCTTCGCCGCTCGCCACCAGCATGAGGATCACATCGCTGCTGGCCTCCTCGTGGGCGAGCTCGAGCGTGAGATCATGCGCCCGGAAGGCGGCGATGATGTCGTCGTGGAGGCGCGGGCCCTCCTTGCGCGGAGGCCAGAGAAAGCGCTCCTGCTTCAGGTCCGCGACCCTCAGCGTGCGCCGTGCAGCGAGGCGATGGCTCTTCGACATCACGACGCCGACGCGCTCGCGATACAGCACGCGGAAGCGGAAGAGCGGGTTGTCTTCCGGCGAATGGTAGCCGTACCCGACCGAGATCTTGCCATCGCGCAGCGCGGCGACCTGCTCCTCGCTCGGCAGCGGCCGAAGGCGTACCTCGACGCGCGGATGACGCGCGCGGAACGTCTGCACGATCCTCGGCAGCAGGAGGGTGTCAGCCAGGGCCCCGTCGAATCCGACCACGACCGTCCCGATACGGCCTTGCGCCGTCGCGCGGGCGTCCTCGACCGCGAGCGCGGCGCGAGCCAGGGTCGCGCGCGCACCTTCGAGGAAGCTCCGGCCGGCGGCGGACAGCTTCACCCCGCGTCCCGAGGGCACGAAGAGCTCGACGCCGATCTCAGCTTCGAGCTGAGCGATTTGCCGGCTCAAGGGCGACTGCGAGACGTGAAGCCGCTCGGCCGCCCTTCCGAAGTGCTCCGCTTCCGCGACGGCGATGAAGTACCGCAGGTGACGTAGCTCCATGATTCAGACCTATAGGGTCTGAAACCGTTGCGATCAATGTCCTGGTGGTCTTGAGCGCGACGGTGCAGGCTGTTCAACATGAGGCGACACGAGACGCTCGAGAAGCTGTCGCCCGGCTTTCTTGGGCCGGCTGAGCTGGCGCGCGGCTGGGCGTCGCGCGTCGACTGCTCGAGCGCCGACGCAAAGCACACGCTGGGGCTTCTGTTTCGCTGAGCCTCGCGACCGACAACCGAGAGAACCCGAACATGACCGAGAACAACCCCACCTCCAGCTCGGAACCAAAGGAGCGCGCGAGGCCCGCACCCGAGGCGAACCAGATGATGCAACGTCGCCCCGCCGGCGCGCTGCTCGTCGCCGGGGCAGTGATCTTCTTCCTCGCCGAGTTCATCGCCGCCGCGGCATGGACGGATCCTCCCTACAGCTACACGCATCACTACATCAGCAACCTGGGAGTCCGTGGCCCCCTCGAGGCTCTTGGCCAGTTCATGAAATCGCCACTCGCGTGGGTCATGAACACCGGGTTCTTTCTCTTCGGGATCATGTTTTTCATCGGTGTCGCCGCGCTCAAGGGCCTGCGAAGCTGGCGCCGCTGGGCAGCGCTCATCCTGGGAGCTCTCGTCGCGCTTGGCGGCGTCTTGCTGGCGTTCAACCCCGGTTCCGGAGAGCCGCCCGACGGCGCAGTCGACTATCACGCCCTGGGCGCCTTCGCGTCTATCGTCGGAGGCAACGTGCTCGCGATGCTCCTTGGACGCCAGCGTCAACAAGTCGGAGTCACTCCCAAAGCCGGGAGGGCCATGGTCGTCCTCGGCGTGTTCGGGCTCGCCTCGATGGTGGCCTTCCTCGTGGTCGCCAGCTCGGGGGCCAACGTCCTCATCGGCCTCGTCGAACGCTGCGCCGTCTATCCCATCATGGTCGGCTTCATCTGTGCGGGGGCGTCGATCTGGAATCGCCGGACCGTTGCACGCTCGAGCGGCGAGGGCGAGACTTCCCGACCACAGATGCTGAAGCAGCAGCCAGCCTACATCAACATCATCAAGATGCGCGCCAAGGCGGGAGCGAGCGCCAAGCTGTTCTAGCTAGCCGCGGCCGGCCTACGAAGCAGCAGCTCATGCAGCTTCGCGACCTCCGCCTTCGACCACGCTCGTGCTCCGCGACCTCGACAGCGGCATGAAAACCTGTAACATATCCACAGAACAGGCGCTCTTCTGCACACGGATTGACATGCGATTGGAATCCATGAACACCAACGCCGCCTATCGCTCGCTTGTCCGTCTGTCCTTCCTCATGCTCCTCGCGGTCGTCTTCTCCATCGGGTGCAAGCGGCTCAAGACCGGCGCGCGGGAGGAGTTCGGGAGAAAGCACAGCTGTCCCGAGGACCGCATCACGGTCCGCTCACGCGACGACGTGAAATGGGGCGCGATCGTGCTCGCGAAAAGACCCGCTGAGGCGCCGCCCGACGAGGTGAAGAACGACCCCGGCCGGCTGGCGAAATGGCAGAAGGACCGGGCCGAAGAGGACGCAGCGACGCGGGAGAGTCTGGACGAGCTCGACGTCTTCGAGGTGAAGGGCTGCGGCCACGAGGTGTTCATGGCCTGCGCGCACCCCGGCGGCGGTGCCGGCGAGGGGGTCGCGACCGACGAGGTCGTGTGCTGGGAGCAGCCCACCACGAAGCGCTGACGCGGTCGCTGGCCAGGCGCGTCAGTCACGGCGGCGCTGCTGCAGCGGCCGCAGAGGAGAGCTCGCTCGCGAACAGCACGGCGCGTCCGGGCCGCGCCGCTCGGGCTCGTTCCCGATCATGAGATGAGGGCTCCGCTCGCGCGCCGGACGAGCGAGGCAACGCGCAGGAAAAGGAGAACCATGCTGAAGCGGATCTGGGATCGTCATCGCGCCGCCGGGCTCGACGAGGCTGCGGCCGCCGCCGCGGCGCCGTCGCCGGAGGAGCTCTGCTACCTCGCGATGCTGGCGTTCGCCGACGAGCGCACCGCGGACGCCGCGGCCTTCGCCGCCCGCGCCGCGGAGGCCTCGCCGGGAGACCCGCTGTTCCGCGCGGCCGCGGCGCACCTCGCGCGGGTCGACCGGGAGGGGAAGCGCAACGTCTACGTGTCCGCGGAGGGGTTCGCCGCCTTCATCCGCGGCGGCGGCAATGTGCCGCTCTACCGGGAGACCAGCGCGGCGCTTGCCGGCCAGTACCCGGAGGCGCCCTTCGATCTGCTCGACATAGGCGCTGGCGACGGCATGGCCCTGCTGCCCGCGCTGACGCCGGCGGTGCGGCGGGTGACCGTGGTGGAGCCGGCGGCGCCGCTGCTCGAGCGGTGCGCCGCGGCGCTCTCGGCGCGGGGCGTCGGCTTCGAGGCCTTCAGCGGGCGATTCCAGGACCTCGCCGCGGATCCCGCCATGGCGTCGCGGAGCTGGGCGGTCGCGCAGGCGACCTTCTGCCTGCACGCGATCGCCCCGGCCGAGCGGCCGGCGCTGCTCCGCTGGGCGCGCGCGCGCTGCGATCTGCTGCTGATCGCCGAGTTCGACGCGCCGCGCATGGACGAGCCTTCGCTGACGGGACTGTCGCGGTGGACATGGATCCGCTCTCGCTGCTGTGCCGGCTCGCCGCCAGCGTCCCGCCGCCGCGCTTTCACACCGTCAAGTACGCGGGCGTGCTCGCCTCGGCAAGTCGCCCACGTCGGCGCGCAAGCGCATCGGACCGCGCCCTGCGGAGCCACAAGAGCCTACGAAGGCGGACGAAGACGCCGCTTCGAAACGCAAGCGTGGCGGCTATCGGGCGGTCGACAAACCGCGCCGAGCTCTTGCGCCGCACATGTGCGATCGACGTCCTCGAGTGCCCAGCTTGCAAGGGGCGGATGAAGCGCGTCGCCATGGTGACCGAGCCAAGGAACATCGCCCGCTTCCTCTCCGCGCTCGGCGAGCCGACCGATGTTCCAGCACGCTCTCCCGACGTCGCACCAAGCGGAAGCGGTCGACAAACCGCGCCGAGCTCTTGCGCCGCACATGTGCGATCGACGTCCTCGAGTGCCCAGCTTGCAAGGGGCGGATGA

Protein sequences of DBSCAN-SWA_3

>NC_021658|11179203:11248868|11240792_11241293_-|WP_020739847.1|transposase|DBSCAN-SWA
MSYPLTVELDGFNVEAAVRIEGYDDEGRERLVRYCARPCFALERLSILRDGRVAYQVKYPRRKGTHRVMTPIVFFARLAALVPPPRHPLVRYHGVLAPAGMDPTRAQSPSPGPGELAMVDPTPRAAVIASLAATLSRAVALGDAEAARVVHEAIGQLLGLPVAPEG
>NC_021658|11179203:11248868|11208269_11209118_+|WP_020739816.1|DBSCAN-SWA
MLIVVLFHDADREVLERLETHLQAALRSGEARLWHRDKILPGQDQDLALKESLKEASVFILLLSADFNASWNKHSYETVLVRGTSARQLPLVVPVLAKPCILSGLPYARLRCVPQNGQPLWRDGRLDEHRLYLAATEILNSVEEAYERLFSEHAETKTDIPNPDLYELIITSERERFRLEKALDSQKATSATAQIDATGSSILSDETKDERNDAYRRGIAEGELMGRRTTLLRLVARAGIPLTTSDLSRIQGCGDVATLDRWIDNSLSAKTAADVLSLRRLA
>NC_021658|11179203:11248868|11187107_11187743_+|WP_148314286.1|DBSCAN-SWA
MELLSKPTKRIGFGLIAVVALVGAYTLGRTSVEVPEKFQTHQDTASTSGTDLQSIISATQERLISCENALYRREQPLHKKEEQPHIKQDEPTASSHSEGSTECGTISQKKELQMMAKDCREFRKSFDAYKAILENDKIDCETILAIRDLAQSQHSTCVAIITANEDASYQNLMRDPNISELVEDAYTFRDDEYSGLSVNGLVKNKRCLVEQ
>NC_021658|11179203:11248868|11195198_11195798_-|WP_148314288.1|DBSCAN-SWA
MGPRWRAALLHGRHGAQLWALGRQPAVIAICRRTRSDEPPAHGTVAPIGQGALEEPRRAATARNGDPRRRHAVPGAQPADVTTPTGPFQGGGRAAVMPPTLPAAHGHAERGLDDEALHTLIEREPIAAPADVAGSPSSLASARPQLCERNPLRTHCCVRKTHTVPVRRAPLAHRVLLGAPVGGNQPPSRRQRRGAVVPP
>NC_021658|11179203:11248868|11232030_11234727_+|WP_020739839.1|DBSCAN-SWA
MIREIMFHPEFTTPFGLQPSGPIGDLGRIVILVGQNGAGKSRYLQLVKDLLETAPRATQEHATLTEDLLRLKAQLAATGADALPPERHVQATREVETKTQRLAFVTRLLASGGVLVDGPGGLVPPTAQDIGIDLTIRPFGLSEAGASRRDPLREAYRSAPDILERAARALFNAEHPALAKTPEVVESAREAARLNDILAALLDKQIQPDVDMTSGAVHARLGERRFDTVELSSGERVLLTWAVTLHREASQLRDAVLFIDEPEVHLHPAVSIRLLSRLFDDKVLGPRGQVWIATHSPVVLLAADAARVLLVEQGALRWSDVSSPQVLDGFFPGTPPQVRFAPRLPVGGSDFRKLRRDHLRYVDKTAFIAEVLQNPAEVLLFSRPRRFGKTLNQSMLRYFLEKTGEERSDLFKGLSIWDDKESRQHFQGYPVVALTFKDVKASTWTECRNTMALTIANAFEEHGYAVKTGALSEREAERFDAIMRNTADNAQLRDALRLLSEALSRQHHQRVVILIDEYDTPIHSAYLHGYYDEAIEFFRNFLSGGLKDNPNLFKGVLTGVLRVAKESLFSGLNNVVSYSLLRPEFASHFGFTEEEVMQLLRESGEDNRQEELRAWYDGYRFGDDTIYNPWSVANYLNQRDRMPRPYWTDTSDNELLKRLLFHEGAGLHGELQALLRGEPIHTIIAEDVVLRNIGDRHDAVWSLLLFSGYLTPSSKPSADAEQRLDVKIPNKEILHAFERLARENLAERMGGEEEVRKLTQALMDGDARTFEGLLERYLLNCMSSQSAAGRAPEMFYEGFLLGLLVRLRADHHVESQPNAGLGRADILITPRSSGRPGVVLELKTLKDGGDVEPALDAGLQQIEDRRYTAKLEERGAHPIHAYSAVFDRQRVWVRKRTM
>NC_021658|11179203:11248868|11246066_11246897_+|WP_148314292.1|DBSCAN-SWA
MTENNPTSSSEPKERARPAPEANQMMQRRPAGALLVAGAVIFFLAEFIAAAAWTDPPYSYTHHYISNLGVRGPLEALGQFMKSPLAWVMNTGFFLFGIMFFIGVAALKGLRSWRRWAALILGALVALGGVLLAFNPGSGEPPDGAVDYHALGAFASIVGGNVLAMLLGRQRQQVGVTPKAGRAMVVLGVFGLASMVAFLVVASSGANVLIGLVERCAVYPIMVGFICAGASIWNRRTVARSSGEGETSRPQMLKQQPAYINIIKMRAKAGASAKLF
>NC_021658|11179203:11248868|11192406_11193969_-|WP_020739803.1|DBSCAN-SWA
MVAIGHVWEGHEILNEERGMVRHFLARQIGDKRDLVWLHVRDGTPLDETVFAEDIARLQHLSDEVPEIVRVLYGGVSGSVAWAATPVLSDAIPLVDATRENDLGPADLKVLIDIGRCLMRAHALSIIHGALSPDRVFIVGDGRYAITHFGFARLFQLGAEEARQDPYGYAPPELISGGRLGPRADVYGFGTLMYELLCKRALSPWAPHRSFPAGIPPVLQVMIKTALYEDPKRRQPSIEKMLSVLTPFAREWEGLGGPPELPHAHIFAEPSGSRRAPHEEAPISVEDEAERSVSGEQGRRASEFPTPRASDAPDAVKSVVPPRDDIAHAPPVATPRPSGAPDTLKSAMPPRNARDTVSHAPPVVSRLRSAELPDLDPMLPVLPPPSTPPRSPVLPVPPALSISPRSSGSTRRSSPVRLLGAVFTLAIVLGSAGALLLLWWQSPRRAAPRLARLVQHVQVAALRASTEPPPQPSDARQAPPPVEPRAVTGRRAVFTQQAVRTPSKDDDICYGLVACGQHKY
>NC_021658|11179203:11248868|11206567_11208163_+|WP_020739815.1|DBSCAN-SWA
MRLTKAPQLWKSGVLALLGEEAARSDELLADLIEREIVARRGEHRFAGEEEYAFQHALVRQAAYAMLLDRDRQVGHGLAGAWLERAGEPDPVVLAEHFERGAVRGKAALWHARAAERALRSLDLAPALSSARRGLAMEPEGELLPELWVHVTEAAAYTGDHAEAMKAAEEVMARASVGSSTYCRALGLALLLALMLRRPEALSTLMDRLLRTQPAADAIMSLAHALSTAVFVLLIGGQRDAAALFLGRLRAIAAPVVEEDPSVKAYVDEASAFWESYVERNPWAAMRLHAAAGQRLAIAEDLLSMPHSIAFMGWDCATLGAFEEAEGCVERALSLSRSARANVPLARLVMANVRLGERRLDEAVAAATAALGEALSQSEGVIIMAAQLALAEARLLRGEFDAAMEVLGGSSAGTSGLVTVDAMARGLRAKILLARGRAGEAAREAEQVVALVRGAGVYDARHASLLLTRAEALDAAGEAEAARAAIREAREDLLARAARIEDPAYRRSFLERVPEHARTLLVARAWLGEED
>NC_021658|11179203:11248868|11204793_11206482_-|WP_020739814.1|DBSCAN-SWA
MKDATPNTAIRRTLGYPRVSTREQEIAGVSLDAQAEKIGNYCRLHSLPEPILFPEVESGGEENEANRKKVAALLADVRRGDMVIVTDIDRFGRDVVFIVKNVRQIMRKGAVFVAIDKGFDSRSPMAEDTLANWAVGAEQERRRIKERTEGGRKHLRVQGYFVEGRPPFGYERQPKPKGTKMPLPLRVVPEHAVVVRRMFALSLEGRSVFEIAKRLRQEYGNVKAFGRAWVLIALRNRVYTGRIAKTAVRPKATRGAVQLPAEWVPAHEAIVDDETFNNVQLALRDRRRGRKPQAESATANHLLRGICRCAECGGSVAAIPVPRSSRHKVGYYVCRGHVEQKEKGVRCKSSAWLRQPDADAAAGEQFMAFTSSLLTSLTRPPRQIEKPDFAAQRREIKIARQRVVEFVAKRLFTVEDVKVELNRLDDSLAAIEAKEAEFKETVGNDTIETRKHAHAYVQQIADEWSILQVDVQRALIRAFSSKVEATKDKQIRITWRDPSQISAAHGAQELPALRPAPIAVALPVPSTVTSLSTNVAALPAPSMSARDYLGSSESAPAPVRGR
>NC_021658|11179203:11248868|11236695_11237232_+|WP_148314291.1|DBSCAN-SWA
MNLDKKMLDALAAAALNADDPLDVCEAVKEEMRERVLRAALEAEGWNLNAAARRLKRSTSTVQYALEHTYTVLNVERLGRLASANEQASPAAAAAPKADASRRTVLRGKREMNNTGGFERSRAPGSTRYRTRPRDQEKKQALSTCAVLRGHHPYGHRARWRTGQIQRHCELGLAHNHS
>NC_021658|11179203:11248868|11242645_11243992_+|WP_080682530.1|transposase|DBSCAN-SWA
MASAARTTGVVYERRRPEKTTLYEIVRDNVETLYGAIDDGAIAVRMPKHAKKELEACLDFGLLCRGFARLRCERCEESRLVAFSCKGRGFCPSCLGRRMCSTAANLIEDILPEVAHRPWVLTFPFPWRRRLAQDGALFGVLTRIFVESVERFYEERGARRGACGAVKSGAVTVVQRTSGDMRLNPRLHVVFLDGAYHEDGTELVWNELGHLRTREVGQVLEHAVGRTLRTLRRHGHLEIEHEVEEDGEPEAALCASAVSGREPRHTSSPRNGSGGSRRLRRARSRTISRCALRSMASPCTQRRAPVRAMPRRGRRCCVTCCDPRSQRSASSRSRTAWCGCRSSAPSLTGLSRWTWIRSRSCAASRPASRRRAFTPSSTLACSPRQVAHVGAQAHRTAPCEARRAYEGGRRRRFETQAWRLSGGRQTAPSSCAAHVRSTSSSAQLARGG
>NC_021658|11179203:11248868|11241597_11242212_-|WP_080682793.1|transposase|DBSCAN-SWA
MLAPHAKQRSLAVPKATGKARKGEQRAGADSAGSDDKKKTTTITPLPARQAPKGPARGMETPSRRRDERSEAAPSAVSERGARDVAVGALLTMVHGAVERERVSTALGAVLPWADVGFVSEGISVRHLDRLLDGLLLATSPRVEWAKLLRRTYAVDVLACPRCSGRMRLMAAITDKATARKILSHLGLFAEPLECRARYPADPA
>NC_021658|11179203:11248868|11223498_11224110_-|WP_044986612.1|DBSCAN-SWA
MPWPEPVTLRGRHAALEPLTHAYQDDLVDAVRDGELWDLWYTYIPRPEGVRDEIERRLSLQRSGSMLPFVVIDARSGRAIGMTTYMDIDAANRRVEIGSTWYRKSVQRTAINTECKLLLLQHAFEALECIAVEFRTHFFNHQSRRAIERLGAKLDGVLRSHRRASDGTLRDTCVYSIIAPEWPTVRSHLNHQLSKPREPAPAR
>NC_021658|11179203:11248868|11226336_11227023_-|WP_080682525.1|DBSCAN-SWA
MNSMVKSTDLQVVEVEGSGTVSLPPDSLRTNVSVEIRGESLEAAREEAAARTRAIVSALEGLQIPSLQVRNVGVSVSPIPEGETERDRLAPPRIIGYEATSTVSVILEGAPLDVLRVESSRILEAALSAGANQTSGIRFFLSAPQEAYRAALKASIVDAERNAGAIAEAAKIKLVGWRSVSSAGEDDGGRAWQMAASRIGPRSTTFPIEPGEIEVTATVRARFRFAKR
>NC_021658|11179203:11248868|11190241_11191831_-|WP_044986604.1|transposase|DBSCAN-SWA
MERWSPPVELSRQEQALMKRLTRVRALFGFLRLHRHELFDETFQEQLEGMYRTTGAGEPPHPPALMCMVTLLQGYVGASDAEAVELAVVDLRWQMVLGCLGADTPPFSQGALQAFRERMVAHEMDRVLLERTVALVRSGAMTEGERRAVSKALRVAIDSRPLAGAGRVEDTINLLGHAARSIVRVVSKITERPPEEICRKAGIPLLLAPSIKAGLDLDWSDPKQKAAAIQILERQVSSLQQWVDRHLDDVVEQPLRTYLDAVTQVRDQDLETAEDGTVRIRQGVAPDRRVSIEDAEMRHGRKSRSKRFDGYKEHIARDLDLPVIVACAVTPANRPEEEGAAPIAEDVQRQRLRLVELHIDRAYVNSPVVDDVIRAGGQVFSKPWGQRARSPDLFSKRDFKIDLRAKTITCPAGQVEVFEPGDTVEFDPEECGACPLRAKCTQAASGRGRTVSIAEDEALQGKFRKLQQTGPGRAVLRQRTAVEHALAHIAARKGHSARYIGARRNLFDLRRAAAIQNLEAAQRLIPEAA
>NC_021658|11179203:11248868|11198941_11200996_+|WP_020739808.1|DBSCAN-SWA
MIERLGDLGDLFRQFREMKKLTQEGLAERCGATVNRTQIALLEQGRRLPKPESLRAIAEQLGIPGETWAPFARDESHLRQQFEASVGELVGRVVGLRSMDIESVHAAEATTKTLFSGMLTATQSFDTLNSILLFYAVPRMSRAFFDRYLGGTAFQSIELFDAAIRRFHEEAIRLFSTFAEAYRKMNASNNLSTILEPLAARDLSAYTDRTVWDAPDPASLEGNRILPIPEHKLEFLGYISAAKYKAQKRKRETLAKYLRELAKEVRAKGPHALDEFGEKRRRKIDSLMRELGSTMAHTPISPLFVSNAANLENEANRILRDEKDEAEMERIQAQALSNLSHYISADHMDVYVATSMRSTSDFVSVNRFVARLFRHDQIAPLRLRYFNPTQSWIEDRVAKGLVEALMLRRASVTLYMAQKADSFGKDSEASVALGQGKPVIVYVPKLVLPSAGLDSESLMAETDLRLREMLLAQGRTAEDLDDLDHDGLFTEALTARIIALSDKQITEIVHLHWADFALLDESERIRGKDVKEKEAKDQDTDQKKDEDQMRRATRLREEYTKFVSAITRGELPELTSELRVEVERILVATTVGFEIRRARLFKEVHPLALQIILSTGVLNGILVSRSVDSCAYLLRGLLENKLQLELEPDDTNYRLLEKTTRSTVRVIARNTLLNNALDGLYDRL
>NC_021658|11179203:11248868|11225243_11226242_+|WP_044986614.1|DBSCAN-SWA
MRERSARWLWAALCLPGVGCTTVVGLDKPYHPIEDQGGGGGGGVETGRRCAGLPATCGPKEDESCCASELVVGGTFNRSNDPAFSATVSDFQLDRFEVTLGRFRAFVDAYPGSRPAPGAGEHPLVAGSGWDAEWEDRLPPDRAELLKGLFCDSEETAWAWTDEPGANERLPMNCVSWYMAFAFCAWDGGRLPTEAELGYAAAGGAEQRPYPWSTSTDDETLDRDHAVYACNGSDAAGCVIEDLLPVGSKSPQGDGLFKQADLAGGMWEWTLDYHGDYPPECVDCAVTTGGTERAMRGGGWRSAAEALHLATRDHRTPTTRAAGIGARCAREP
>NC_021658|11179203:11248868|11213966_11215085_+|WP_020739822.1|DBSCAN-SWA
MSAADLDPRGAAGEPGRPALITGGAGFIGSNVAHRLLQAGESVILFDNLSRPSVARNVDWLKRVHGDRVTLVAGDVRDAVAVAEVVRRASSVFHFAAQVAVTTSLVRPAEDFEINARGTLNVLEAIRAQSAPPPLLFTSTNKVYGGLPDVPLQRRDRQYAPEDPKLRAAGISEARPLDFHSPYGCSKGAADQYVIDYARTFGLPAAVFRMSCIYGPRQFGTEDQGWVAHFLLQALRREPITLYGDGMQVRDVLFIDDLVDAFLLARKNIRQVSATAFNIGGGPENTVSLLELLDLIEELDGKRPATGFEAWRPGDQRYYVSDCRRFNAATGWWPRVRFRDGVRKLHGWLREMTGAGKAAGQAAEELCMEGAE
>NC_021658|11179203:11248868|11211248_11211605_-|WP_020739819.1|DBSCAN-SWA
MIVVTNRIPVAEGHEAEFEDRFKNRVHLVDRAPGFLRNEVHRPKPMKLDHATGAWSPDPDAQGFYEVKTWWRSMDDFIAWTRSPAFAEAHRNRAPKEMFAGPSKLDIHEVFLSTDLQG
>NC_021658|11179203:11248868|11212851_11213970_+|WP_020739821.1|DBSCAN-SWA
MASHVLITGGAGFIGSHVADELLRQGHRVRALDNLIPQVHGPERRRPAYLDPEVELIVGDVRDRDAVKSALRGVDVVYHFAAMVGVGQSMYKIAEYTSVNNLGTAVLLEELAERPVSRLIVASSMSVYGEGLYRTASGAVVPGAGRPLDQLKRGDWEVRSEAGEALAPIPTPESKTPALESVYALSKYDQERLCLTIGRAYNIPTVALRFFNVYGRRQALSNPYTGVLAIFASRLLNDRPPLIFEDGLQRRDFVSVADISRACVRVLSADAAVGQVLNIGSGRSYTVREVADHVRKVMGKDRIEPEITGKSRLGDIRHCFADIGAAQRKIGYEPQVTLEEGLRDLAGWLEGQVAKDAVAQARAELESRGLTV
>NC_021658|11179203:11248868|11215081_11216383_+|WP_020739823.1|DBSCAN-SWA
MRFALVNPPWSFEGSIYFGCREPHLPLEYGYARALLEAAGHEAALVDAQARGLSQAALRDEVAALRPDAIVVTTAPSYLFWRCAPPELRVPQQTLHALRDVPGLRFAVGPHASTTPRATLRKLGVDAVVMGECEEVLVQLADLPRARWGEIASIAYVEGEEARVQGGPRASDMARLPALRWDDATVARHAHHHHRFDAAPVGPGAEIEASRGCPYHCTFCAKDNFRDRYRKRPLAVLLDELDGLVAQGVRYVYFIDEIFLPDRPLLEALVDRPVSFGIQMRIDNWSREMLDLLGKAGCVSIEAGVESITKEGRSLLAKHCRLSTEQLSDLLIHAKKSVPFVQANLIQSQTDDPADVAAFRERLRQHGVWANEPVPIFPYPGSPDYTTRWGLPDDQAWERSVAHYLGQFDHFSDLQESRPLPLSELEVAAPGHG
>NC_021658|11179203:11248868|11221071_11222082_+|WP_020739828.1|DBSCAN-SWA
MSAALRILVTGGAGFVGSHLCDRLIRDGHEVIALDDFSTGARGNVAHLLLHRRFRLVEHDVTQPYDLQVDRIYNLASPASPPHYQRDPVRTTLINVVGAFHALKLAEGCGARVFQASTSEVYGDPEVHPQPEGYRGSVNPIGIRSCYDEGKRCAESLVMDFHRRRGVEVRMARIFNTYGPRMALDDGRVVSNFIVQALKGEDLTVYGAGSQTRSFCYVDDLVEGIVRLMEHPTETGPVNLGNPEEFTVLELAEEVIRLTGSRSRIAFRPLPQDDPRQRQPVIDHAKRVLGFEPKVPLRAGLRRTIEGFRSVLGLGRHAPALAASEGDAALPQAANG
>NC_021658|11179203:11248868|11238646_11239183_+|WP_020739844.1|DBSCAN-SWA
MNDTNITVAHGSPRISDRIDNVLREHGSKSSGSLHAIASAAGRCGLVAILLGFGFYKFTAVEAEAIAPLVSNSPFMGWLYAVGSVRTVSAGVGVTEILVAALLAVHRWWPKAALLGGLAGMLMFLTTLSFAFTTPAATSDPELLGFLVKDLFLFAASAHAASASLRAAAYRARTGVTK
>NC_021658|11179203:11248868|11239269_11239947_+|WP_020739845.1|DBSCAN-SWA
MRKMTFISSITGLGMVLAGCVSHKEASSDRIKAEREAAQVVFDEQGEALLPKGYRSWVHVSTSWLPITTSLLDGMITKTPELFNTYVEPIAFKTYVKTGEWPDGTLFAKEFTTTRVDAECDGPPAYVCKRWYGKAIFQSAYTGVAIMLKDKKRFPNEPGNWAYFSFGHQPPPYQPASPPRARERCAQCHIDRAGPKLDYVFSVERIGLDRAGDSRRDILEASLPD
>NC_021658|11179203:11248868|11230858_11231164_-|WP_148314289.1|DBSCAN-SWA
MSERAVKDAEVLRLAAVYIEAMNNLNQRLAELASADPTLSPNVRHASSGARNAAAGASPSANHAFIKLAKEYHDFHGVQMTDEELLLDARKHGLASIEVLP
>NC_021658|11179203:11248868|11222158_11223472_+|WP_020739829.1|DBSCAN-SWA
MKQPQKLAKPEGKLAVLLPGLGAVSTTTIAGVMLARRGVAAPVGALTQLGTIRLGKRTDNRSPRIKDFVPLASLDDLEFGGWDIFPDNAHEAAVEAKVLEAAHLDAVREELAAVTPMKAVFYPDYVRRLHGPHVKTGRSKADMVEQVRDDIRGFVRSRGASRAVAVWCGSTEIFIAPSEVHRSAAAFEAGLLSNHPAISNSQIYAWACIKEGVPFANGAPNLTVDFPAAWELARSHGVPIAGKDFKTGQTLMKTVIAPALKARMLGISGWFSTNILGNRDGVVLDDPDSFKTKEASKLSVLEQILQPELYRELYSKLYHKVRIEHYPPRGDAKEGWDNIDLFGWLGYPMQMKVNFLCRDSILAAPIVLDLALLLDLAARAGFSGTQEWLSFYFKSPMTAPELYPEHDLFIQSMKLKNTLRWMMGEELITHLGNEYYD
>NC_021658|11179203:11248868|11227183_11228551_-|WP_020739834.1|DBSCAN-SWA
MKTLYALLTLLVPSHLLAGAPADSAPPDRAAPARGGERCGCAGDEPGPLAGQLDPAFGEAGTGIARVRFGADDDGGFFDVDVADDRIIAAGWGQGGLGGIRFRVVRLTGAGAPDSTFGDGMVTTGWANSTGDMAYLAATGRQQGGEIVAIGWRDRFRDASADVALARYAEDGSLDPGFGDGGKSLLDLGGDEEIRGGLVAPDDGIVAVGQRDGRLLIARATADGARDTSFASPRGYRTVSLGAASVAEAVALDDRGRVVVAGAVERGGQRDMIVIRLRGDGALDRSFGRGGAIVAGDPGIDERAVALALSPGGGIVVAGDAGAEGARDFQVRRFHPNGAPDLAFGDGGVAAWPTTGGDDVAEDMALLPGGAVLVAGNGGERGEGGTTTPLLVRYTCDGALDPAFGEGGVLPVDLGEFGQLHTVEVVSDDQVLLGGGDVGMSPGPGTYGVVARMWM
>NC_021658|11179203:11248868|11183363_11186036_+|WP_020739801.1|DBSCAN-SWA
MRAGELVDDRFALEAQVGAGGMGTVWRALDRATGEAVALKFLRDPVGGNAARFAQEARILAAIEHRHVVRYLGHGLAPTREPYLAMEWLEGEDLAARLSRGGLTLEDSLSLVERAAFALGAAHARGIVHRDVKPSNLFLVGGEVTRVKLLDFGIARQPGALATLTQTGAILGTPGYLAPEQAQGEREVGPQADVFALGAVLFECVTGSAAFRGMQVMALLAKLLLEEPPRLIEVCADVPRELSELCHRMLAKDPGARPAHGAAVAEALARIPRGAALRAAPRHDAARAPIGTTERRLVSILAIAPPQDEPAGQDDATAPVAGASWKIVRDAVQPLGATVDVLADGTMLVVLAGAGDATDQAARAARCALRVHAGLPRAGMALVTGRGDTTERQQVGEIVERAATLLGRMRAHGSASGPVMVLDEVTRALLDTRFEVTESGELSVLVRERMLGEHPRLLLGRPSPFVGRDREMQRLLGFLEDAFEDRRAVAATVTAPAGMGKSRLRLELMGRLSDRVPNLAIVIGRGDSLGAKGGLGLLGSGLRGALGLEAGERPSAQQEKILSAVKRYVAGDAAERVAEFLGELVGAPFPDEKSPRLRAARHNAQLMAEQVESACLEFMRAVTRRGPLLWVLEDLHWGDPASVKLCDVALRELEDEPFGVLAFARPELHEIFPRLWAERHAQEVRLGPLSKRAADAMVSAALRDPAAARQVAALVERAEGNAFFIEELIRAAVDGRSDTLPETVLGMVEARLSALPLEARRLLRAASVFGDRFCKRETNSTRKNNIEQFQALRGYARPGRRSAGGDGGRCVRAIGGARAVLVADHRGRGFGTRCAWGRSYGGAEPDVGSFHRAPLRLQKAGPPSQVRRTRPSLVASAGVQAARGRGTAGL
>NC_021658|11179203:11248868|11202487_11203303_+|WP_020739812.1|DBSCAN-SWA
MSDGSAIEWTDATWNPLRGCTKVSPGCKHCYAETFAERFRGVPGHPYEQGFDLLLVPDKLFEPFRWSRSRRVFVNSMSDLFQDKVPEEYVRQVFEVMASADWHIYQMLTKRAARLLTLTSRMPPEIVHRRHIWLGVSVEDRAYGLPRIDELRRTPAKVRFLSIEPLLEDLGRIDLQGIDWVIVGGESGPRARPMEERWVLSIRDQCREAGIPFFFKQWGGVQKSRAGRHLGKRTYDEYPTIEPAAPPPAAVRAQRLAVIRDQFLRGGMAAE
>NC_021658|11179203:11248868|11235373_11235991_-|WP_020739841.1|DBSCAN-SWA
MTTPVDTRSMRERMLAGDLYMGDPELAELSAAALDLMAAYNATSARQRPLRRRLLEQLLGAIGEGTEIRPPFYVDYGAHITIGARCFANFGLVALDVAPITIGDDVQIGPNVQLLTPTHPLDPEPRRQKWEAAKPIAIGNNVWLGGGAIVLPGVTIGDNTVVGAGAVVTRDLPANVVAVGNPARVIRTLDGASAGAAPAAGDARG
>NC_021658|11179203:11248868|11247042_11247498_+|WP_148314293.1|DBSCAN-SWA
MRLESMNTNAAYRSLVRLSFLMLLAVVFSIGCKRLKTGAREEFGRKHSCPEDRITVRSRDDVKWGAIVLAKRPAEAPPDEVKNDPGRLAKWQKDRAEEDAATRESLDELDVFEVKGCGHEVFMACAHPGGGAGEGVATDEVVCWEQPTTKR
>NC_021658|11179203:11248868|11210130_11211069_-|WP_020739818.1|DBSCAN-SWA
MSALTPGRRDGGVARFRPPGPRPGRGAGPERPRVEAARGRPPRTPGKALFLLPNLITLSSIFCGLDAVRRAAAARSDDDFRRAASLILFAMLLDALDGRVARMTRTDSAFGRELDALADLVSFGVAPAVLVHQWALHRLGLAGVLGGFVFAACGAIRLARFNVLSLAEAGGSSAPPRYVVGLPVTGAAGILVAIVMTHGFEDGQLAGVGVAPAVLATTLLLSLLMVSTLRFRSFKDVRLDARAALSIALVIGSSALISTRWAPGYVLVWLIGAYVLLGVAESLWRPPARRRGAPGEPAAALGACPRGGEERV
>NC_021658|11179203:11248868|11180864_11182487_+|WP_044986602.1|DBSCAN-SWA
MNRARGSTTAILLAFFFMACGPSTSATEPEGSGGSGSGAGGPGSVAGSSTSTGGSTGSGGTDASASTGSGGAGGEPPGDGGAGGSSTGGGPPVVEPTLITSGPNDYWKTGTPTEVTSGNADVTVDEATTHQRWDGFGGTFNEVGWNVLSMLGEAERARAIELLFDKHEGAAFAYGRIPIGASDYAMDRYTLDETPNDTAMASFSIDRDKERLIPYIKAALVVRPGLHLWASPWTPPTWMKSNGAFDGGRMKDDASTLQAYALYLAKFVEAYAGEGITIEAVHPQNEPNYETRYPSCTWTGALMAKFIGTYLGPTFADRGLTAQIYLGTMSNNESGKDGAIISAVTGDATAMGYVKGFGLQWNMMSSASGLRSRNLPIVQTEHKCGNYPWNPTGSPPFDAQKAPNDHAYAEESWGLIRDWIKAGVTSYSAWNMVLDTAGKNLDSERPWPQNALLTVDTAAKTLNVTPVYHVFRHVSEYVDPGATRVATTGGDALAFKNPDGSIVTILYNSGNAAKMTVLDVAGKKLQFSVPAHGWATVNWT
>NC_021658|11179203:11248868|11228756_11229656_-|WP_020739835.1|DBSCAN-SWA
MTLTIDANTNDVIDLPECVRLLSGIKGISRRERMDDAARYLRMLSNNKSFLIELVNRQICEAQPLDAYQQSSNFSQQIVDLGGGPGFRLRANMWPRCVADAPADWERSLFAYQMPHDHNADFLTVGYWGPGYETDIYEYDPERTVGFEGEQVDIRFLERTRLTNGKVMFYRANRDIHTQLPPDDFSISINLLVADPEAVQSTKQYWFDVERGVISSSVERLDYSPFVFLCRLASMVGDGATINVLEKLAQGHSDARIRAEAFTALATLDPGSSLRHWRDASEDVDPYVQRVARAKLSAE
>NC_021658|11179203:11248868|11234787_11235363_-|WP_020739840.1|DBSCAN-SWA
MARASARRAAPARRARRHDPGRRDRLVATALDVIAEQGVAGASHRSIARAADVPLGSTTYHFASIDELLAAAFTRHAEAAASRFEARMRAACGREAAVELLVEHLTADLLGSPRDLVLSVELYVAAARRPALRAVTQAWMLRSRRALELHFDPVTARELDALIEGLVLHSALSTDPMTAEQIRHAIRRFAR
>NC_021658|11179203:11248868|11230593_11230788_-|WP_020739837.1|DBSCAN-SWA
MHTSEAVSSSPVRAQQFVLEDLDEPIAPATPVTSVAGGVLLVVIVLAMVPGAVDTSYRKSPDPQ
>NC_021658|11179203:11248868|11229671_11230502_-|WP_020739836.1|DBSCAN-SWA
MITAQLSSFSAAISETYNIEEPSTFWTCRPHFERLLGSGFLADLLSTQLGYCLSGQGEVIQAATGSSARVMLPSGVQIDILLLDPTVDDDKLLSYPSHVLMGFASASDDARLVLERYRHVEPYRNDVFDGRAMLEKQPDQVLRSMDVSEVSAGWEVFRLRSVDRPIPLVLLQSKPFLDFAWQYDPGTLMPMQAICPNSSAYRLFYTTKLLGEVTGRGNIESLLRISEYKSHFVRWSALQALFAVDAEAGRARLAGAVDDPHPRIRGAAKKALARLG
>NC_021658|11179203:11248868|11187742_11188522_+|WP_148314287.1|DBSCAN-SWA
MRSRITRGELGALPAFMLDQLALRILLGLGVITVSELASAQEKESQGAFYWDGFHINGIFQAKLPLLLRLGVSYSGGTAPGAVHVAMLNFGQTLSLAKELNVGYLLGVGLSKERMSTVEDKVLGIHATFETGPFRASAATNLQFYALGEAIIPMFTTVLRGQGAIFRTTHVDAFVGGDLFLRNLNVQFGATTGFRFRDVVLFDRNISGLLSATVMNTWASVPAHGLSWAAYVEPRLGVVVDLETKEEEKRDQIYEYGQY
>NC_021658|11179203:11248868|11193962_11194829_-|WP_020739804.1|DBSCAN-SWA
MQEAEKAAKRLEIARAREYWAQIYALDPTPMAICQLGQYDLRLDRLEQAAEELSKCVEQMPAPTNDLERRRYEVRHADLAAVRQRVAELQVSAPPDTARILVDGREVSGGRRVFVAPGQHEVTATGKQGQVAHALVKVAAGDSRHVSLSFEVPKSSSAKSRAPARVAPASGRSRRNPWIIGTGAAGSVALLGAGVGLRLASDAAERETAAKVSRLYDGSMLPSSARFSKVYDEANAANTRANVFQGLGTAALITGAALGVATVVYVVFPRGKAEIRTRAGGAEVKLVW
>NC_021658|11179203:11248868|11197223_11197568_-|WP_020739806.1|DBSCAN-SWA
MLEGVTYSNVGSVAFSALCRYALRFIPSRRPQEYSVPALTPSCSANTRADCPLLCQRATRSRQMRALSSIHTSGADLYAAQELQDSMLVAERVLTYEVGPPGKGGTRGIVRARW
>NC_021658|11179203:11248868|11218681_11219827_+|WP_020739826.1|DBSCAN-SWA
MNRRPTSSRPLDIAFFGSSLVSAYWNGAATYYRGIIRALAARGHRVTFYEPDAYDRQKHRDIDDPPWARVVVYSGTDADEPRRLVQQARSADVVVKASGVGVFDELLEAEVAALDRPGLTTVFWDVDAPATLERVRASASDPFRAQIPRYGLVFTYGGGDPVVRGYEALGARRCVPIYNALDAETHFEVAPDPRFDCDFALLANRLPDRERRVEEFFLRPAAALPELRFLLGGNGWQDKAMPPNVRYVGHVYTADHNAFNASARAVLNVARDSMASVGFSPATRVFEAAGAAACLVTDAWEGIELFLEPEREVLVARDGDEVAAILRALTPERARAIGEAAKQRVLAGHTYAERAKQVEALLGRPDGAADAADATLTAIAP
>NC_021658|11179203:11248868|11211850_11212417_+|WP_020739820.1|DBSCAN-SWA
MNDSETARGARSAAGLDRSEMEGVVRRNIQALLQVRKESERNKGFQEALADAITKFTGSMTFVFLHATVFGGWIVVNTGVIPGLKPFDPFPFVMLAMIASVEAIFLSTFVLISQNRMQALADKRADLDLQINLLAEHEVTRLIELVDGISRHLKVPRTSDPHLEELKKDVHPEVVLEEIERAQRDITE
>NC_021658|11179203:11248868|11203312_11204605_+|WP_020739813.1|DBSCAN-SWA
MAKYDWSDGPATLGPHSLAKHAILREYIERYIPILTRGGTVPLKLMLIDGFAGGGEYVVEGHGSTLHPGSPLILINAVRAAEARMNAVAGRKKPFSVEASYVFIEKNPTTYAYLDATLKRHVGESFVRDKVDLRRGAFEEELGGILDQIKGTSPRRPRPIFVLDQYGYRAIPVDLIRRIMTEIPTAEVFLTLAVDHISAHARTAGEALGRLKDARLVEPELEAFLSGRRDMDEAATLSSEDRGRLMRLIQFILHETFAKRAHAECYTPFFITSKRSHRSYWFLHLANSSKANDVVKALHWSVSNHFEHFGREGTMMLGFDPAKNKYQAVLPFPFEFDDSAKARTVRALVEELPVIFQARHHDGVSLKALYKALCNETPADLETLGDAVNRLCADLEFEKRGANGEEREVSTKVKDSDIIRPARQGRLFRK
>NC_021658|11179203:11248868|11224255_11224900_-|WP_020739831.1|DBSCAN-SWA
MASITPDKKKIKSFPTEAELEAWMAANHAQETELWLRIYKKGSGVPTVTQAQALDVALCWGWIDGIRKSLDESSFLQRYTPRKSRSVWSQINRDHIARLTAAGRMTPHGQRQVDAAKADGRWDAAYAPMRSATAATLPDDLRAAIEANPRAREALQTLGRQNLFALAFRMSNMKTPAGRAKKIADLVAMLARGETIVPERRKEPKAIRPPEKPR
>NC_021658|11179203:11248868|11217548_11218685_+|WP_020739825.1|DBSCAN-SWA
MRIVLFCHSLLSDWNHGNAHFLRGVVTELTERGHEVRVFEPRDAWSLQNLVADHGEAPLREVRDVYPHVDPIRYDLASLDLDEALEGAALVIVHEWSEPELVARVGAHRAGASYRLLFHDTHHRSVTDPGAMARYDLTHYDGVLAFGRVIRDLYLERRWARRAFVWHEAADARVFRPRREIQPERDLVWVGNWGDEERTRELDEFLIGPARDLGLSARVHGVRYPEHARAALEAAGVEYRGWLPNHRAPDAFARARVTVHVPRRPYVASLPGIPTIRPFEAMACAIPLVCSPWSDAEALFSPGLDYLVARDGEEMKKHLRALLAEPAMAAELAERGRTTVLARHTCAHRVNELLCISADLGIEVDRPAPAATTQRATA
>NC_021658|11179203:11248868|11244921_11245821_-|WP_020739852.1|DBSCAN-SWA
MELRHLRYFIAVAEAEHFGRAAERLHVSQSPLSRQIAQLEAEIGVELFVPSGRGVKLSAAGRSFLEGARATLARAALAVEDARATAQGRIGTVVVGFDGALADTLLLPRIVQTFRARHPRVEVRLRPLPSEEQVAALRDGKISVGYGYHSPEDNPLFRFRVLYRERVGVVMSKSHRLAARRTLRVADLKQERFLWPPRKEGPRLHDDIIAAFRAHDLTLELAHEEASSDVILMLVASGEGLSLCPESAASTLLAGVVFKRVRDLNVVILGRSVWRAMDDKDPLVRSLLEITNSVHGSSQ
>NC_021658|11179203:11248868|11182514_11183186_-|WP_020739800.1|DBSCAN-SWA
MLVRLLSLPLAGLALACASPEPVPASAPTGPAPAEPAAPAPSPESAPPTSGGDPGFDHDVSGVVGAPPPAWDVGPWYNSPPLTPADLRGKVVLVRWFMSPSCPLCSATAPALKALDERYRSRGLVVVGMYHHKDDEPLDPAAVKGYLSHFGYSFPVAIDPDWRTLKRWWIDGHPKRQYTSVSFLLDRAGLVRHVHLGGQLAPDTPEFATVEGRVRALLDEPAR
>NC_021658|11179203:11248868|11219823_11220933_+|WP_020739827.1|DBSCAN-SWA
MKTLSFVFLGLSITSSWGNGHATTYRGLLKRLAQRGHRVLFLERDLWFYAENRDLPDPPYGRTELYQGLDDLRARFGDAVRDADMVVVGSYVPDGVEVGAWVTETARGKTAFYDIDTPVTLKKLERGDTEYLSAALIPRYDLYLSFTGGPTLDLLERRYGAKRARPLYCSVDPDAYFPERRSPRWDLGYLGTYSPDRQPTLDRLLVEPARRWAQGRFAVAGPQYPADIDWPSNVDRTDHIPPGEHRAFYGAQRFTLNVTRRDMIEAGYSPSVRLFEAAACGVPVISDDWPGLDELFEPGKEILLARSSEEALRLLREFPERERVAIGQRARERVLARHTAAHRAEALERYARELLHEQDERELPGDRGS
>NC_021658|11179203:11248868|11216375_11217545_+|WP_020739824.1|DBSCAN-SWA
MVDALPSPGSVLMTADTVGGVFSYAIELARALAERGVRTSLATMGGPLSAPQREAAGRVPGLAVFESSFRLEWMDDPWDDVARAGDWLLELEERVRPDVVHLNGYAHGALGFRAPKLVVAHSCVLSWWTAVLGGEAPPRYDRYRREVARGLAAAAAVVAPTQAMLDALVRHHGALAPFRGARAAVIPNAADPDRFAPGPKDEVIVAVGRLWDQAKNIAALGEVAPRLPWPIQVAGSDVHPGGGSRPLPSLEHLGVLSPSGVAAALARASICAHPARYEPFGLSVLEAALSGCALVLGDIPSLREVWGDAALYVDPGDTEALRRALAALVDDPVRRQDMASRARARAAAFSPRRMARGYLHLYGELLGGSSRTRRSPAREAPRAAAVGGE
>NC_021658|11179203:11248868|11237622_11237889_+|WP_080682528.1|DBSCAN-SWA
MVQEASFALLVLTAEDETADGTFRAQQNVVHETGLFQGRLGFSRAIVLVEDSVEVFSNLDGVQQIRYSKGNIGETFGDVLATTRREFR
>NC_021658|11179203:11248868|11248133_11248868_+|WP_187345740.1|transposase|DBSCAN-SWA
MRRGALGAGRRLRGLQRAIPGPRRGSRHGVAELGGRAGDLLPARDRPGRAAGAAPLGARALRSAADRRVRRAAHGRAFADGTVAVDMDPLSLLCRLAASVPPPRFHTVKYAGVLASASRPRRRASASDRALRSHKSLRRRTKTPLRNASVAAIGRSTNRAELLRRTCAIDVLECPACKGRMKRVAMVTEPRNIARFLSALGEPTDVPARSPDVAPSGSGRQTAPSSCAAHVRSTSSSAQLARGG
>NC_021658|11179203:11248868|11179203_11180679_+|WP_049949754.1|tail|DBSCAN-SWA
MRSMSSMLARFVRVRVPLLVWALAAAACAAEPPLDGEVGPEAALLGEHGDALSTRVRLMAANLTSGTNQSYDPGHGQRILQGVEPDIVLLQEFNYGNNSTSAIRGFVDATFGTGFSYYRETGAQIPNGIVSRWPIVASGEWDDASVGNRDFAWARIDIPGPADLWAVSVHFLTSGSGARNTEAQQLVSFIQAHVDPDDYLVIGGDFNTGGRDEACVTTLSSVVVKPGSYPADKNGNDKTNASRSKPYDWVLVDSDLEPLETAVVLGGSSFANGLVVDTRVYSPLSEISPALSSDSGAPSMQHMGVVRDFVIPDGSGGSVSSSSSGGSGGSGGAGGGTANVIINEVLANEPGSDPDGEFVEIINVGTATASIGGWKLADSTGTRHTFPAGASLAPSTAVVVYGHASAVPAGVIGAVGASTGALGLNNGSDTVTLRNAAGAAVSSVSYTSALSNQDGVSMNRSIDLDGSTSFVLHTTFGGNSSPGTRADGTSF
>NC_021658|11179203:11248868|11209248_11210079_-|WP_020739817.1|DBSCAN-SWA
MITPDAPLGSPTAPAQRPPAGLAPLERPGFGAGLKAMLGGYGYLFRTPDLWPLALVPTSLALVLTVVLAIAGVKVAPSLVELIVKEPGTGWLWTVLMAALRVLSLAVVLVAALALSFGLAKPLSGPALERMVRRAEADLGAPAWPEVGFFADMWRALQSSLVALAFTLPILIVLGVVGLLFAPASVVVVPLQLAVAALAGAWDLCDCPLSIRGVPVAARIEFVRRNLAAVMGFGFGLALLSFLPCSLLIVLPAGILGAARLVVTLERWEATKRAPR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049949754.1|11179203_11180679_+|tail	lamin tail domain-containing protein	NA	NA	NA	NA
WP_044986602.1|11180864_11182487_+	glucosylceramidase	NA	NA	NA	NA
WP_020739800.1|11182514_11183186_-	redoxin family protein	NA	NA	NA	NA
WP_020739801.1|11183363_11186036_+	protein kinase	M1HC50	Acanthocystis_turfacea_Chlorella_virus	8.2e-15	29.9
WP_148314286.1|11187107_11187743_+	hypothetical protein	NA	NA	NA	NA
WP_148314287.1|11187742_11188522_+	hypothetical protein	NA	NA	NA	NA
WP_044986604.1|11190241_11191831_-|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_020739803.1|11192406_11193969_-	protein kinase	NA	NA	NA	NA
WP_020739804.1|11193962_11194829_-	hypothetical protein	NA	NA	NA	NA
WP_148314288.1|11195198_11195798_-	hypothetical protein	NA	NA	NA	NA
WP_020739806.1|11197223_11197568_-	hypothetical protein	NA	NA	NA	NA
WP_020739808.1|11198941_11200996_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_020739812.1|11202487_11203303_+	phage Gp37/Gp68 family protein	A0A2P1A0W3	Gordonia_phage	7.1e-71	50.3
WP_020739813.1|11203312_11204605_+	three-Cys-motif partner protein TcmP	NA	NA	NA	NA
WP_020739814.1|11204793_11206482_-	recombinase family protein	A0A1X9I6J1	Streptococcus_phage	6.1e-08	24.4
WP_020739815.1|11206567_11208163_+	hypothetical protein	NA	NA	NA	NA
WP_020739816.1|11208269_11209118_+	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_020739817.1|11209248_11210079_-	EI24 domain-containing protein	NA	NA	NA	NA
WP_020739818.1|11210130_11211069_-	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_020739819.1|11211248_11211605_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_020739820.1|11211850_11212417_+	DUF1003 domain-containing protein	NA	NA	NA	NA
WP_020739821.1|11212851_11213970_+	NAD-dependent epimerase/dehydratase family protein	M4QPK0	Synechococcus_phage	1.4e-37	32.0
WP_020739822.1|11213966_11215085_+	SDR family NAD(P)-dependent oxidoreductase	A0A2K9L4U8	Tupanvirus	1.5e-23	27.9
WP_020739823.1|11215081_11216383_+	TIGR04295 family B12-binding domain-containing radical SAM protein	NA	NA	NA	NA
WP_020739824.1|11216375_11217545_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_020739825.1|11217548_11218685_+	glycosyltransferase	NA	NA	NA	NA
WP_020739826.1|11218681_11219827_+	glycosyltransferase	NA	NA	NA	NA
WP_020739827.1|11219823_11220933_+	glycosyltransferase	NA	NA	NA	NA
WP_020739828.1|11221071_11222082_+	SDR family oxidoreductase	A0A2K9KZK0	Tupanvirus	5.7e-70	43.3
WP_020739829.1|11222158_11223472_+	inositol-3-phosphate synthase	NA	NA	NA	NA
WP_044986612.1|11223498_11224110_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_020739831.1|11224255_11224900_-	YdeI/OmpD-associated family protein	NA	NA	NA	NA
WP_044986614.1|11225243_11226242_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	NA	NA	NA	NA
WP_080682525.1|11226336_11227023_-	SIMPL domain-containing protein	NA	NA	NA	NA
WP_020739834.1|11227183_11228551_-	delta-60 repeat domain-containing protein	NA	NA	NA	NA
WP_020739835.1|11228756_11229656_-	hypothetical protein	NA	NA	NA	NA
WP_020739836.1|11229671_11230502_-	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_020739837.1|11230593_11230788_-	hypothetical protein	NA	NA	NA	NA
WP_148314289.1|11230858_11231164_-	hypothetical protein	NA	NA	NA	NA
WP_020739839.1|11232030_11234727_+	AAA family ATPase	NA	NA	NA	NA
WP_020739840.1|11234787_11235363_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_020739841.1|11235373_11235991_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_148314291.1|11236695_11237232_+	hypothetical protein	NA	NA	NA	NA
WP_080682528.1|11237622_11237889_+	nucleotide-binding protein	NA	NA	NA	NA
WP_020739844.1|11238646_11239183_+	DUF417 family protein	NA	NA	NA	NA
WP_020739845.1|11239269_11239947_+	cytochrome P460 family protein	NA	NA	NA	NA
WP_020739847.1|11240792_11241293_-|transposase	transposase	NA	NA	NA	NA
WP_080682793.1|11241597_11242212_-|transposase	transposase	NA	NA	NA	NA
WP_080682530.1|11242645_11243992_+|transposase	transposase zinc-binding domain-containing protein	NA	NA	NA	NA
WP_020739852.1|11244921_11245821_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_148314292.1|11246066_11246897_+	DUF998 domain-containing protein	NA	NA	NA	NA
WP_148314293.1|11247042_11247498_+	hypothetical protein	NA	NA	NA	NA
WP_187345740.1|11248133_11248868_+|transposase	transposase	NA	NA	NA	NA