CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_021807	Streptococcus pyogenes HSC5, complete sequence	2 crisprs	DinG,csm6,cas3,DEDDh,csa3	0	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_021807_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021807_1

954161-954262

Orphan

Consensus_repeat	Method
AATAATTGGTATAGTCTAATTATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021807_1

>merge|NC_021807|1|954161-954262|CRISPRCasFinder
AATAATTGGTATAGTCTAATTATACCGATAAAAACAGTATGTTTACAGTATATAATATCCACAATGTCTTGTCAAACATAAAATTGGTATAGTCTAATTATA

>NC_021807|1|1|954161-954262|CRISPRCasFinder
AATAATTGGTATAGTCTAATTATA	CCGATAAAAACAGTATGTTTACAGTATATAATATCCACAATGTCTTGTCAAACA
TAAAATTGGTATAGTCTAATTATA

Protein	Signature genes	Signature genes Name	Protein_function
NC_021807.1\|WP_002984449.1\|954285_954843_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NC_021807.1\|WP_002984447.1\|955060_956563_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NC_021807.1\|WP_020833516.1\|964516_965305_-\|streptococcal-pyrogenic-exotoxin-SpeL	unknown	unknown	gnl\|CDD\|280949
NC_021807.1\|WP_002984433.1\|962092_962878_+\|hypothetical-protein	unknown	unknown	unknown
NC_021807.1\|WP_020833513.1\|946777_948013_+\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NC_021807.1\|WP_009880829.1\|948382_949156_-\|CAMP-factor-pore-forming-toxin-Cfa	unknown	unknown	gnl\|CDD\|369335
NC_021807.1\|WP_002984469.1\|941876_942125_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NC_021807.1\|WP_002989648.1\|942487_944806_-\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NC_021807.1\|WP_042361506.1\|961013_961385_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NC_021807.1\|WP_002992417.1\|951016_951658_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NC_021807.1\|WP_002989626.1\|951764_952100_-\|alkylphosphonate-utilization-protein	unknown	unknown	gnl\|CDD\|225380
NC_021807.1\|WP_011054546.1\|964213_964402_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|269889
NC_021807.1\|WP_020833512.1\|945335_946658_+\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040
NC_021807.1\|WP_002984451.1\|952295_954110_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NC_021807.1\|WP_014635494.1\|949525_950362_-\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217
NC_021807.1\|WP_002984444.1\|956625_957639_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NC_021807.1\|WP_002992415.1\|950377_951007_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NC_021807.1\|WP_002989607.1\|963008_963623_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NC_021807.1\|WP_002992425.1\|961384_962083_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NC_021807.1\|WP_020833514.1\|957718_960829_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|180917

Protein	Function_ID	Function_description	E-value
NC_021807.1\|WP_002984449.1\|954285_954843_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.3728e-38
NC_021807.1\|WP_002984447.1\|955060_956563_-\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NC_021807.1\|WP_020833516.1\|964516_965305_-\|streptococcal-pyrogenic-exotoxin-SpeL	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	2.95713e-08
NC_021807.1\|WP_011054546.1\|964213_964402_-\|hypothetical-protein	gnl\|CDD\|269889	cd06603, GH31_GANC_GANAB_alpha, neutral alpha-glucosidase C, neutral alpha-glucosidase AB. This subgroup includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae.	0.00788697
NC_021807.1\|WP_020833513.1\|946777_948013_+\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	7.19968e-96
NC_021807.1\|WP_009880829.1\|948382_949156_-\|CAMP-factor-pore-forming-toxin-Cfa	gnl\|CDD\|369335	pfam07373, CAMP_factor, CAMP factor (Cfa). This family consists of several bacterial CAMP factor (Cfa) proteins which seem to be specific to Streptococcus species. The CAMP reaction is a synergistic lysis of erythrocytes by the interaction of an extracellular protein (CAMP factor) produced by some streptococcal species with the Staphylococcus aureus sphingomyelinase C (beta-toxin).	2.06073e-97
NC_021807.1\|WP_002984469.1\|941876_942125_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.43969e-13
NC_021807.1\|WP_002989648.1\|942487_944806_-\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_021807.1\|WP_042361506.1\|961013_961385_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	4.94991e-49
NC_021807.1\|WP_002992417.1\|951016_951658_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.99371e-71
NC_021807.1\|WP_002989626.1\|951764_952100_-\|alkylphosphonate-utilization-protein	gnl\|CDD\|225380	COG2824, PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism].	2.02984e-64
NC_021807.1\|WP_020833512.1\|945335_946658_+\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
NC_021807.1\|WP_002984451.1\|952295_954110_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_021807.1\|WP_014635494.1\|949525_950362_-\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.58337e-109
NC_021807.1\|WP_002984444.1\|956625_957639_-\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NC_021807.1\|WP_002992415.1\|950377_951007_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	5.61041e-111
NC_021807.1\|WP_002989607.1\|963008_963623_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.14841e-31
NC_021807.1\|WP_002992425.1\|961384_962083_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.0817e-63
NC_021807.1\|WP_020833514.1\|957718_960829_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|180917	PRK07279, dnaE, DNA polymerase III DnaE; Reviewed.	0

>NC_021807.1|WP_002984451.1|952295_954110_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSRESTYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKDLVAEKVQALLTTTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>NC_021807.1|WP_002989626.1|951764_952100_-|alkylphosphonate-utilization-protein
MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVVLDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMKLKSEFVKKI
>NC_021807.1|WP_002992417.1|951016_951658_-|amino-acid-ABC-transporter-permease
MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPFKPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEIFRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVYVLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ
>NC_021807.1|WP_002992415.1|950377_951007_-|amino-acid-ABC-transporter-ATP-binding-protein
MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLLRMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTITMGKQKSDAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEPTSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK
>NC_021807.1|WP_014635494.1|949525_950362_-|amino-acid-ABC-transporter-substrate-binding-protein
MIIKKRTVAILAIASSFFLVACQATKGLKSGDAWGVYQKQKSITVGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKIDVIWNGYSITKDRQEKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYDSLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLENYRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANIKS
>NC_021807.1|WP_009880829.1|948382_949156_-|CAMP-factor-pore-forming-toxin-Cfa
MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQANLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKAQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNRLNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS
>NC_021807.1|WP_020833513.1|946777_948013_+|cation-diffusion-facilitator-family-transporter
MTQDPIANLKLARKGPIVSIIVYLLLSVAKLLAGYLLNASSLIADGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLIHTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLADAVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLKKYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQFSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQTVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQRTSIWRRHESWSLLFHQITPIAKKQLHHTHYRIVKM
>NC_021807.1|WP_020833512.1|945335_946658_+|sodium:alanine-symporter-family-protein
MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAFKLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGMATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIGTFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYILSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESGLGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLTQSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILMVGLGGFLKLELIWVLADIVNGLMAIPNLIALLALSPVVILETKHYFIK
>NC_021807.1|WP_002989648.1|942487_944806_-|DNA-helicase-PcrA
MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHIGYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQAADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVDEYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVLLEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVASTISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIAYLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKGKAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIEEFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAKGLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLFGKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQARKAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLEVSGSGKTMELKIKFPEVGLKKLLASVAPIEKK
>NC_021807.1|WP_002984469.1|941876_942125_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN
>NC_021807.1|WP_002984449.1|954285_954843_-|signal-peptidase-I
MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKSGDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYLEKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLINASQIKGLVTFRVLPLSDFGFVEVE
>NC_021807.1|WP_002984447.1|955060_956563_-|pyruvate-kinase
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKVIDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK
>NC_021807.1|WP_002984444.1|956625_957639_-|6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
>NC_021807.1|WP_020833514.1|957718_960829_-|DNA-polymerase-III-subunit-alpha
MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKLHMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMEILHMLHAIRDNLSLAETPVVESDQELTDCQQLTTFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLIKIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDAKDYSATEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
>NC_021807.1|WP_042361506.1|961013_961385_+|GntR-family-transcriptional-regulator
MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIAGVNPNTMQRAFTELEREGMVYSQRTAGRFVTNDQKLIARKRRELAISELESFITNMTKMGFSHTEIIPVLTSFLKEDSQ
>NC_021807.1|WP_002992425.1|961384_962083_+|ABC-transporter-ATP-binding-protein
MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKTTLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFYSDFDNSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDPAARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEYQQSIDSLFRETYKV
>NC_021807.1|WP_002984433.1|962092_962878_+|hypothetical-protein
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNINTSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ
>NC_021807.1|WP_002989607.1|963008_963623_-|TVP38/TMEM64-family-protein
MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSNALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIIIGSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVMITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH
>NC_021807.1|WP_011054546.1|964213_964402_-|hypothetical-protein
MLTYDEFKQAIDDGYIVGDTVMIVRKNGQIFDYVLPHEEARNGEVVTEEKVEEVMVELDYIK
>NC_021807.1|WP_020833516.1|964516_965305_-|streptococcal-pyrogenic-exotoxin-SpeL
MRIFLHQNCRLVNMSTTFFIVVLSLMVFSVRMVSAEGTINIKDIYPPRWDVDKTLSPTTLREIYNRDTIKKVNKPITGKRGTQVIMDAQHKTKVWEFDDYNFIISSNLHPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIYMNVFIDGHKKDDTSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYDSKVLSGNWEFHGSGEKEEGADLFKYPDYRYNNLIDIDKKSHIDVYLFTNKEN

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Crispr_ID: NC_021807_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021807_2

1666345-1666444

Orphan

Consensus_repeat	Method
TTCGCAATTTTATCTTTTACTGTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021807_2

>merge|NC_021807|2|1666345-1666444|CRISPRCasFinder
TTCGCAATTTTATCTTTTACTGTCTCATCCAAGATTTTTTTAAGGGTACCAATGGTTTCTTTATTTTCTTGCTCCTTAGCAATTTTATCTTTTACTGTCT

>NC_021807|2|2|1666345-1666444|CRISPRCasFinder
TTCGCAATTTTATCTTTTACTGTCT	CATCCAAGATTTTTTTAAGGGTACCAATGGTTTCTTTATTTTCTTGCTCC
TTAGCAATTTTATCTTTTACTGTCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021807.1\|WP_042361535.1\|1651237_1652866_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173883
NC_021807.1\|WP_020837811.1\|1656280_1656481_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NC_021807.1\|WP_003059481.1\|1654785_1655589_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NC_021807.1\|WP_002982458.1\|1674944_1675619_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NC_021807.1\|WP_002987954.1\|1659133_1660054_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	unknown	unknown	gnl\|CDD\|238499
NC_021807.1\|WP_002991237.1\|1672967_1673621_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_021807.1\|WP_020837816.1\|1667218_1668850_-\|transcriptional-regulator-Mga	unknown	unknown	gnl\|CDD\|285470
NC_021807.1\|WP_020837817.1\|1669853_1671482_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NC_021807.1\|WP_020837810.1\|1655572_1656199_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049
NC_021807.1\|WP_020837814.1\|1664238_1665339_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|274008
NC_021807.1\|WP_002982472.1\|1669524_1669776_-\|hypothetical-protein	unknown	unknown	unknown
NC_021807.1\|WP_020837812.1\|1656649_1659121_-\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|273578
NC_021807.1\|WP_002982439.1\|1677729_1678026_-\|DUF4298-domain-containing-protein	unknown	unknown	gnl\|CDD\|372919
NC_021807.1\|WP_011285226.1\|1675605_1676874_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|223914
NC_021807.1\|WP_002982520.1\|1653952_1654774_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NC_021807.1\|WP_002993552.1\|1673714_1674932_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NC_021807.1\|WP_020837809.1\|1652978_1653956_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NC_021807.1\|WP_020837819.1\|1677297_1677582_-\|hypothetical-protein	unknown	unknown	unknown
NC_021807.1\|WP_020837818.1\|1671582_1672971_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_021807.1\|WP_020837813.1\|1660316_1663871_-\|C5a-peptidase-ScpA/B	unknown	unknown	gnl\|CDD\|173801

Protein	Function_ID	Function_description	E-value
NC_021807.1\|WP_042361535.1\|1651237_1652866_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173883	cd08518, PBP2_NikA_DppA_OppA_like_19, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_021807.1\|WP_020837811.1\|1656280_1656481_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	4.12165e-05
NC_021807.1\|WP_003059481.1\|1654785_1655589_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.85753e-80
NC_021807.1\|WP_002982458.1\|1674944_1675619_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	8.84255e-116
NC_021807.1\|WP_002987954.1\|1659133_1660054_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	1.92404e-123
NC_021807.1\|WP_002991237.1\|1672967_1673621_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.27645e-69
NC_021807.1\|WP_020837816.1\|1667218_1668850_-\|transcriptional-regulator-Mga	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	5.49748e-74
NC_021807.1\|WP_020837817.1\|1669853_1671482_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	6.06461e-59
NC_021807.1\|WP_020837810.1\|1655572_1656199_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.22702e-91
NC_021807.1\|WP_020837814.1\|1664238_1665339_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	4.12262e-11
NC_021807.1\|WP_020837812.1\|1656649_1659121_-\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|273578	TIGR01363, pneumococcal_histidine_triad_A_protein, streptococcal histidine triad protein. This model represents the N-terminal half of a family of Streptococcal proteins that contain a signal peptide and then up to five repeats of a region that includes a His-X-X-His-X-His (histidine triad) motif. Three repeats are found in the seed alignment. Additional copies in more poorly conserved regions may be detected. Members of this family from Streptococcus pneumoniae are suggested to cleave human C3, and the member PhpA has been shown in vaccine studies to be a protective antigen in mice. [Cellular processes, Pathogenesis].	0
NC_021807.1\|WP_002982439.1\|1677729_1678026_-\|DUF4298-domain-containing-protein	gnl\|CDD\|372919	pfam14131, DUF4298, Domain of unknown function (DUF4298). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 94 and 105 amino acids in length. There are two completely conserved residues (Y and D) that may be functionally important.	2.929e-24
NC_021807.1\|WP_011285226.1\|1675605_1676874_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|223914	COG0845, AcrA, Membrane-fusion protein [Cell envelope biogenesis, outer membrane].	3.9346e-22
NC_021807.1\|WP_002982520.1\|1653952_1654774_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.11383e-69
NC_021807.1\|WP_002993552.1\|1673714_1674932_-\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	5.49497e-52
NC_021807.1\|WP_020837809.1\|1652978_1653956_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.84167e-108
NC_021807.1\|WP_020837818.1\|1671582_1672971_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.41647e-30
NC_021807.1\|WP_020837813.1\|1660316_1663871_-\|C5a-peptidase-ScpA/B	gnl\|CDD\|173801	cd07475, Peptidases_S8_C5a_Peptidase, Peptidase S8 family domain in Streptococcal C5a peptidases. Streptococcal C5a peptidase (SCP), is a highly specific protease and adhesin/invasin. The subtilisin-like protease domain is located at the N-terminus and contains a protease-associated domain inserted into a loop. There are three fibronectin type III (Fn) domains at the C-terminus. SCP binds to integrins with the help of Arg-Gly-Asp motifs which are thought to stabilize conformational changes required for substrate binding. Peptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	8.18746e-76

>NC_021807.1|WP_020837814.1|1664238_1665339_-|YSIRK-type-signal-peptide-containing-protein
MTRQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTTVKAEVEPRPLATTGGEKSRKLDELYNELHDENSQLVEEKAALLDKLEELEKEKEKKAEKAEDVERHYLRKLDQEHKEQEERQKNLEELERQGKREIDKRYQEQLQKQQQLETEKQKLTEANQVSEASRKGLSNDLEASRAAKKELEAKHQKLEADHQALEAKHQKLEADHQVSETSRKGLSRDLEASREANKKVTSELTQAKAQLSALEESNKLTEKEKAELQVKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDTKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGEATNPFFTAAALTVMATAGVAAVVKRKEEN
>NC_021807.1|WP_020837813.1|1660316_1663871_-|C5a-peptidase-ScpA/B
MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQAVETPQPTAVSEEAPSSKETKTPQTPDDAEETVADKANDLAPQAPAKTTDTPATSKATIRDLNDPSQVKTLQEKAGKGSGTVVAVIDAGFDKNHEAWRLTDKAKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGTKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKENPQKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKILMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYYQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMKNGYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQVPDKKPETKPEQDGSDQTPDKKPETKPEQDGSGQAPDKKPEAKPEQDGSGQTPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTRDQLPTTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRQKETKK
>NC_021807.1|WP_002987954.1|1659133_1660054_-|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb
MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKNAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
>NC_021807.1|WP_020837812.1|1656649_1659121_-|pneumococcal-type-histidine-triad-protein
MKKTYGYIGSVAAILLATHIGSYQLGKHHMGLATKDNQIAYIDDSKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAIISEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVAKGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVPHGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPGRRKAPIPDVTPNPGQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSEHSKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVGYMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATVKYVMQHPEVRPDVWSKPGHEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQPEGVQFYNKNGELVTYDIKTLQQINP
>NC_021807.1|WP_020837811.1|1656280_1656481_-|CsbD-family-protein
MSEEKLKSKIEQASGGLKKGAGKLTGDKELEAKGFVEKTIAKGKELADDAKEAVEGAVDAVKEKLK
>NC_021807.1|WP_020837810.1|1655572_1656199_+|ABC-transporter-ATP-binding-protein
MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTSLSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTVNPLWPMKKSLEEAYYPSQDLRDAFGIQEKWLNRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQASVWKSLLEIVKDRNLGLIVISHDFDMLEKLCDACYMIEENRTQLFKHT
>NC_021807.1|WP_003059481.1|1654785_1655589_+|ABC-transporter-ATP-binding-protein
MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLAIIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVNYLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTCISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITIFKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG
>NC_021807.1|WP_002982520.1|1653952_1654774_+|ABC-transporter-permease
MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKNKAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF
>NC_021807.1|WP_020837809.1|1652978_1653956_+|ABC-transporter-permease
MKRTTIIIIWKIIRCITLIFGVSVLTFVLLKQSPVDPVMASVNYDTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGDLGTSLVYRQPVSDIIRSRAGASFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIFSVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVLSSEYVLFARARGETQWQIFKNHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGLGSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV
>NC_021807.1|WP_042361535.1|1651237_1652866_+|ABC-transporter-substrate-binding-protein
MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELVVSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSFDLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQINIHLTEAHSTFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFKKWTWVLLDENTALAALESGDVDMIYATPELASKKVKGTRLIDIPSNDVRGLSLPYVKEGVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWNPKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVAEQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNITFYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIGDKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK
>NC_021807.1|WP_020837816.1|1667218_1668850_-|transcriptional-regulator-Mga
MYVSKLFTSQQWRELKLISYVTENADAIGVKDKELSKALNISMLTLQTCLTNMQFMKEVGGITYKNGYITIWYHQHCGLQEVYQKALRHSQSFKLLETLFFRDFNSLEELAEELFVSLSTLKRLIKKTNAYLTHTFGITILTSPVQVSGDEHQIRLFYLKYFSEAYKISEWPFGEMLNLKNCERLISLMIKEVDVRVNFTLFQHLKILSSVNLIRYYKGHSAVYDNKKTSHRFSQLIQSSLEIQDLSRLFHLKFGLYLDETTIAEMFSNHVNDQLEIGYAFDSIKQDSPTGCRKVTNWVHLLDELEIRLNLSVTNKYEVAVILHNTTVLKEEDITANYLFFDYKKSYLNFYKQEHPHLYKAFVAGVEKLMRSEKEPISTELTNQLIYAFFITWENSFLKVNQKDEKIRLLVIERSFNSVGNFLKKYIGEFFSITNFNELDALTIDLEEIEKQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDKLNAFLNISFADSLPLDKPIKNPLDFHRKEVILPTPPNKLHAPLHNLDSLTAATQKQIHH
>NC_021807.1|WP_002982472.1|1669524_1669776_-|hypothetical-protein
MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQPSMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD
>NC_021807.1|WP_020837817.1|1669853_1671482_-|CHAP-domain-containing-protein
MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTADTDTDDESETPKKDKKSKETASQHDTQKDHKPSHTHPTPPSNDTKQTDQASSEATDKPNKDKNDTNQPESSDQSTPSPKDQSSQKESQNKDGRSTPSPDQQKDQTPDKTPEKSADKTPEKGPEKAAEKTPEPNRDAPKPIQPPLAAAAPVFIPWRESDKDLSKLKPSSRSSAAYVRHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP
>NC_021807.1|WP_020837818.1|1671582_1672971_-|HAMP-domain-containing-histidine-kinase
MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKREFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDSQNVNIVTTFDNSYSNVKVMSQKVTLHDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLMFSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRLYASLSTSIKSLQKEYERASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFADRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSELKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEAETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWMVFTIDFPSHHDD
>NC_021807.1|WP_002991237.1|1672967_1673621_-|response-regulator-transcription-factor
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLAKRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE
>NC_021807.1|WP_002993552.1|1673714_1674932_-|ABC-transporter-permease
MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTENTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVKNALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYLEKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNINGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLNKSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEAVILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIKASKLDPIEALRFE
>NC_021807.1|WP_002982458.1|1674944_1675619_-|ABC-transporter-ATP-binding-protein
MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNPSFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNIEHSDIE
>NC_021807.1|WP_011285226.1|1675605_1676874_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVNKVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQPLFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVIDRKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLIGSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVEVTSGLTMQDKIAQPLPGMKDGMEVGSIVKP
>NC_021807.1|WP_020837819.1|1677297_1677582_-|hypothetical-protein
MKFKKVLVIPVLALAATCFLTACGTKKDSKKEEVKEIKMSDIKDDAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN
>NC_021807.1|WP_002982439.1|1677729_1678026_-|DUF4298-domain-containing-protein
MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLRNFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36870 : 49183

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042361455.1\|36870_40596_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.6e-40	26.9
WP_042361456.1\|40756_42211_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	9.2e-53	32.3
WP_020833183.1\|42238_43261_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	3.1e-63	41.4
WP_002986700.1\|43428_43983_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_020833184.1\|44166_45714_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	4.4e-45	52.4
WP_020833185.1\|45771_46896_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_042361457.1\|47148_48414_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002987716.1\|48691_49183_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.2e-18	42.3

DBSCAN-SWA_2

339600 : 425089

Bacillus_phage(16.67%)

bacteriocin,protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020833293.1\|339600_344544_+\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_020833294.1\|345316_346024_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_020833295.1\|346263_348264_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	4.6e-87	35.1
WP_010921941.1\|348758_349772_+	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	2.5e-97	53.7
WP_020833297.1\|349775_350264_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.3e-11	37.5
WP_020833298.1\|350230_352411_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	7.3e-171	43.2
WP_042361476.1\|352615_353368_-	ADP-ribosyltransferase	NA	NA	NA	NA
WP_042361547.1\|353825_354248_+	hypothetical protein	NA	NA	NA	NA
WP_002995935.1\|354437_354689_+	hypothetical protein	NA	NA	NA	NA
WP_020833302.1\|354782_355289_-	hypothetical protein	NA	NA	NA	NA
WP_002990844.1\|355649_355886_+	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_020833303.1\|355878_356577_+	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	1.6e-10	25.2
WP_042361477.1\|356652_357612_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_002993065.1\|357944_359282_+	MFS transporter	NA	NA	NA	NA
WP_020833305.1\|359455_360838_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	6.5e-32	36.0
WP_002985793.1\|360871_361426_+	NUDIX hydrolase	NA	NA	NA	NA
WP_002985791.1\|361425_361677_+	hypothetical protein	NA	NA	NA	NA
WP_020833307.1\|361696_362392_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_020833308.1\|362542_362884_+	hypothetical protein	NA	NA	NA	NA
WP_014635325.1\|362982_363630_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_004218965.1\|363775_364708_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002985780.1\|364771_365497_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
WP_011017448.1\|365497_366352_+	metal ABC transporter permease	NA	NA	NA	NA
WP_002990808.1\|366499_367306_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_020833309.1\|367522_369928_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
WP_010921962.1\|369997_370351_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_042361478.1\|370573_371707_+\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_002990800.1\|371920_372346_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_002985768.1\|372451_373141_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_002985765.1\|373462_374191_+	UMP kinase	NA	NA	NA	NA
WP_002985763.1\|374219_374777_+	ribosome recycling factor	NA	NA	NA	NA
WP_020833311.1\|374885_375743_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002990794.1\|375815_376325_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_002985757.1\|376321_376537_+	YozE family protein	NA	NA	NA	NA
WP_020833312.1\|376692_377862_+	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	5.5e-16	40.5
WP_014635330.1\|378175_379948_+	oleate hydratase	NA	NA	NA	NA
WP_010921967.1\|380106_381159_+	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_009880369.1\|381204_381780_+	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_002985748.1\|381938_382436_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_002985746.1\|382416_382824_+	diacylglycerol kinase	NA	NA	NA	NA
WP_020833313.1\|382943_383840_+	GTPase Era	NA	NA	NA	NA
WP_042361479.1\|383859_384336_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_014635333.1\|385497_385944_-	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	4.1e-12	36.0
WP_011528336.1\|386166_386877_-\|bacteriocin	bacteriocin ABC transporter	NA	NA	NA	NA
WP_002994577.1\|386981_387218_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_020833315.1\|387515_387740_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002994581.1\|387717_387894_+	hypothetical protein	NA	NA	NA	NA
WP_072135613.1\|388137_388500_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_028797129.1\|389110_389338_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002994587.1\|389386_389704_+	hypothetical protein	NA	NA	NA	NA
WP_020833317.1\|389769_390051_+\|transposase	transposase	NA	NA	NA	NA
WP_020833318.1\|390083_390437_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.7e-06	35.2
WP_011284470.1\|390482_390653_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.1e-07	46.3
WP_075340231.1\|390692_390908_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.2e-09	43.9
WP_002992578.1\|392850_393600_+	response regulator transcription factor	A0A1V0E029	Clostridioides_phage	2.1e-21	28.0
WP_014635339.1\|393600_394935_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_011017462.1\|395082_395208_-\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_014635340.1\|395284_396649_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_020833322.1\|396659_398813_-	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	5.7e-43	28.3
WP_042361549.1\|399100_399328_+\|bacteriocin	bacteriocin BlpM	NA	NA	NA	NA
WP_003060803.1\|399340_399541_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_020833325.1\|400433_401504_+	hypothetical protein	NA	NA	NA	NA
WP_009880375.1\|401596_401995_+	hypothetical protein	NA	NA	NA	NA
WP_020833327.1\|402342_402612_-	quorum-sensing system protein StcA	NA	NA	NA	NA
WP_142353550.1\|403525_403594_-	peptide pheromone SHP2	NA	NA	NA	NA
WP_002990747.1\|403682_404549_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_020833329.1\|404720_405548_+	DNA-formamidopyrimidine glycosylase	A0A127AWE5	Bacillus_phage	5.1e-16	27.5
WP_002994141.1\|405544_406138_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_020833330.1\|406327_407830_+	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	2.1e-76	42.1
WP_020833331.1\|407951_409145_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_002990729.1\|409141_409288_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_002985700.1\|409333_409570_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_020833332.1\|409663_411997_+	ribonuclease R	Q0GXV6	Lactococcus_phage	6.7e-90	39.6
WP_002994152.1\|411999_412467_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	5.7e-41	57.0
WP_010921981.1\|412472_413192_+	glutaminyl-peptide cyclotransferase	NA	NA	NA	NA
WP_002994169.1\|413308_413956_-	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_002985692.1\|414005_414932_-	DUF979 domain-containing protein	NA	NA	NA	NA
WP_002994173.1\|414931_415615_-	DUF969 domain-containing protein	NA	NA	NA	NA
WP_002994177.1\|415825_416752_-	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	2.6e-77	47.5
WP_002985686.1\|416896_417274_-	VOC family protein	NA	NA	NA	NA
WP_002985684.1\|417284_417950_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_011054264.1\|417998_419084_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_002985680.1\|419257_420259_+	catabolite control protein A	C6ZCU4	Enterobacteria_phage	6.1e-24	28.5
WP_002994184.1\|420389_421388_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_002994187.1\|421389_422724_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_002985672.1\|423145_425089_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.0e-120	38.7

DBSCAN-SWA_3

624711 : 632111

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042361490.1\|624711_626922_-	LTA synthase family protein	W6LM83	Streptococcus_phage	3.2e-267	68.8
WP_002985142.1\|627029_628193_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_002985140.1\|628189_628876_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002992640.1\|628969_630136_+	chorismate synthase	A0A291AU41	Pandoravirus	5.8e-34	32.8
WP_002992643.1\|630196_630538_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	41.1
WP_020833404.1\|630758_632111_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	7.8e-30	23.8

DBSCAN-SWA_4

930686 : 1022274

103

Streptococcus_phage(33.82%)

capsid,holin,portal,head,transposase,tail,tRNA,terminase,integrase

attL 964044:964103|attR 1011017:1011112

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002989678.1\|930686_931571_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_010922363.1\|931686_933027_-	DUF2130 domain-containing protein	NA	NA	NA	NA
WP_002989673.1\|933123_934080_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_002993908.1\|934090_934687_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_020833508.1\|934778_937415_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_020833509.1\|937429_938131_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-36	39.8
WP_002984482.1\|938248_938791_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002984480.1\|938933_939575_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002994467.1\|939737_940226_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984476.1\|940236_940437_-	CsbD family protein	J7KJ36	Streptococcus_phage	1.8e-07	50.0
WP_002984475.1\|940477_941017_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_020833511.1\|941029_941218_-	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_002989652.1\|941228_941840_-	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_002984469.1\|941876_942125_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_002989648.1\|942487_944806_-	DNA helicase PcrA	A7KV33	Bacillus_phage	3.5e-131	41.2
WP_020833512.1\|945335_946658_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_020833513.1\|946777_948013_+	cation diffusion facilitator family transporter	NA	NA	NA	NA
WP_009880829.1\|948382_949156_-	CAMP factor pore-forming toxin Cfa	NA	NA	NA	NA
WP_014635494.1\|949525_950362_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002992415.1\|950377_951007_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.8e-28	35.5
WP_002992417.1\|951016_951658_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002989626.1\|951764_952100_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_002984451.1\|952295_954110_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	5.2e-98	38.9
WP_002984449.1\|954285_954843_-	signal peptidase I	NA	NA	NA	NA
WP_002984447.1\|955060_956563_-	pyruvate kinase	NA	NA	NA	NA
WP_002984444.1\|956625_957639_-	6-phosphofructokinase	NA	NA	NA	NA
WP_020833514.1\|957718_960829_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	2.4e-119	29.8
WP_042361506.1\|961013_961385_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002992425.1\|961384_962083_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
WP_002984433.1\|962092_962878_+	hypothetical protein	NA	NA	NA	NA
WP_002989607.1\|963008_963623_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
964044:964103	attL	NA	NA	NA	NA
WP_011054546.1\|964213_964402_-	hypothetical protein	A3F673	Streptococcus_phage	1.2e-21	84.7
WP_020833516.1\|964516_965305_-	streptococcal pyrogenic exotoxin SpeL	Q938J1	Temperate_phage	1.2e-46	41.4
WP_014635497.1\|965586_966300_-	streptococcal pyrogenic exotoxin SpeM	Q938J1	Temperate_phage	9.0e-78	59.5
WP_014635498.1\|966603_967470_-	DUF334 domain-containing protein	Q938J2	Temperate_phage	4.5e-132	99.0
WP_011017840.1\|967457_967982_-	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_020833517.1\|968121_969327_-	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	4.7e-212	86.3
WP_003058873.1\|969442_969670_-\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_002987582.1\|969666_969942_-	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_020833519.1\|969951_970569_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.5e-76	88.3
WP_002987513.1\|970571_971003_-	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-73	100.0
WP_020833520.1\|971014_972901_-	gp58-like family protein	Q938J9	Temperate_phage	8.1e-219	84.7
WP_010922091.1\|972915_973929_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	2.0e-184	99.7
WP_020833521.1\|973925_975977_-\|tail	phage tail protein	A3F656	Streptococcus_phage	0.0e+00	83.4
WP_011284845.1\|975973_976753_-\|tail	phage tail family protein	A3F655	Streptococcus_phage	1.9e-65	54.0
WP_020833522.1\|976784_980408_-	tape measure protein	U6E979	Streptococcus_phage	3.0e-04	44.4
WP_020833523.1\|980422_980752_-	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	2.2e-10	39.6
WP_020833524.1\|981212_981812_-\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	5.4e-44	57.3
WP_020833525.1\|981821_982211_-	hypothetical protein	B5SP36	Lactococcus_phage	8.4e-46	69.0
WP_002984399.1\|982207_982573_-	HK97 gp10 family phage protein	A0A097BY98	Enterococcus_phage	7.7e-17	46.3
WP_002984393.1\|982553_982862_-	hypothetical protein	A0A2P1JTW8	Anoxybacillus_phage	5.7e-13	40.2
WP_010922219.1\|982858_983212_-\|head,tail	phage head-tail connector protein	A0A2H4J002	uncultured_Caudovirales_phage	7.4e-25	49.6
WP_002990031.1\|983223_983490_-	hypothetical protein	NA	NA	NA	NA
WP_020833526.1\|983501_984551_-\|capsid	major capsid protein	O34062	Streptococcus_phage	1.7e-104	56.3
WP_020833527.1\|984553_984934_-	hypothetical protein	A0A0K2CNR0	Brevibacillus_phage	3.2e-05	33.3
WP_020833528.1\|984943_985477_-	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	2.8e-15	80.3
WP_011284859.1\|985882_986197_-	hypothetical protein	M1PLI3	Streptococcus_phage	6.8e-38	72.8
WP_002988389.1\|986266_986452_-	hypothetical protein	NA	NA	NA	NA
WP_020833529.1\|986455_988018_-\|head	phage head morphogenesis protein	O80166	Streptococcus_virus	1.4e-46	42.9
WP_002984369.1\|987998_989501_-\|portal	phage portal protein	C9W9H5	Streptococcus_virus	1.9e-141	54.5
WP_020833530.1\|989512_990820_-\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	2.0e-184	75.7
WP_042361558.1\|990797_991265_-\|terminase	terminase small subunit	A0A141E1Y3	Streptococcus_phage	2.1e-51	70.1
WP_001132273.1\|991327_991513_+	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
WP_002987543.1\|991564_991942_+	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
WP_002990048.1\|992257_992470_+	hypothetical protein	NA	NA	NA	NA
WP_020833532.1\|992559_993474_-	hypothetical protein	NA	NA	NA	NA
WP_020833533.1\|994051_994486_-	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	1.8e-73	97.2
WP_020833534.1\|994759_995395_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	3.8e-88	68.9
WP_020833535.1\|995396_995681_-	hypothetical protein	A3F628	Streptococcus_phage	1.4e-37	88.3
WP_020833536.1\|995677_996058_-	hypothetical protein	A3F627	Streptococcus_phage	2.6e-36	63.5
WP_020833537.1\|996067_996337_-	hypothetical protein	Q938M2	Temperate_phage	1.8e-39	88.8
WP_020833538.1\|996333_996609_-	DUF1599 domain-containing protein	J7KDH9	Streptococcus_phage	2.9e-32	73.6
WP_020833539.1\|996833_997190_-	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	1.4e-55	91.5
WP_002984338.1\|997173_997524_-	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	2.6e-46	89.4
WP_020833541.1\|997477_998347_-	bifunctional DNA primase/polymerase	A0A1P8BME8	Lactococcus_phage	9.8e-103	65.2
WP_020833542.1\|998613_1000167_-	hypothetical protein	A0A1P8BM51	Lactococcus_phage	1.3e-209	70.4
WP_002984328.1\|1000184_1000667_-	DUF669 domain-containing protein	A0A1P8BM40	Lactococcus_phage	9.7e-60	70.7
WP_075340263.1\|1000671_1002075_-	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	2.3e-194	72.3
WP_002984321.1\|1002110_1002794_-	AAA family ATPase	J7KC09	Streptococcus_phage	9.4e-125	99.1
WP_002984318.1\|1002790_1003075_-	hypothetical protein	NA	NA	NA	NA
WP_002984315.1\|1003071_1003266_-	hypothetical protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
WP_020833543.1\|1003265_1003595_-	hypothetical protein	A1EAC2	Streptococcus_phage	4.6e-13	42.5
WP_002984309.1\|1003675_1003813_-	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	4.9e-17	97.8
WP_011017882.1\|1003809_1004106_-	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	3.1e-48	98.0
WP_011054585.1\|1004184_1004370_-	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011284879.1\|1004536_1004776_+	hypothetical protein	NA	NA	NA	NA
WP_002984292.1\|1004925_1005135_+	hypothetical protein	NA	NA	NA	NA
WP_011017884.1\|1005393_1005903_+	hypothetical protein	NA	NA	NA	NA
WP_002984281.1\|1006010_1006238_-	hypothetical protein	A0A141E1R7	Streptococcus_phage	2.9e-14	57.3
WP_011054589.1\|1006311_1006698_+	hypothetical protein	A0A097PAT1	Streptococcus_pyogenes_phage	1.2e-65	100.0
WP_011284881.1\|1006686_1006896_-	hypothetical protein	A0A097PAQ9	Streptococcus_pyogenes_phage	1.7e-32	100.0
WP_011284882.1\|1006949_1007549_+	hypothetical protein	A0A097PAT4	Streptococcus_pyogenes_phage	3.1e-108	100.0
WP_011285583.1\|1007578_1007737_-	hypothetical protein	A0A097PAP2	Streptococcus_pyogenes_phage	4.8e-24	100.0
WP_020837244.1\|1008096_1008840_+	helix-turn-helix domain-containing protein	A0A097PBE5	Streptococcus_pyogenes_phage	2.0e-80	64.0
WP_011285585.1\|1008875_1009769_+	P63C domain-containing protein	A0A1I9LJQ0	Stx_converting_phage	1.2e-68	47.5
WP_020837246.1\|1009885_1010974_+\|integrase	site-specific integrase	A0A097PAS9	Streptococcus_pyogenes_phage	9.5e-204	99.2
WP_002992581.1\|1012218_1014483_-	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7
1011017:1011112	attR	NA	NA	NA	NA
WP_020837248.1\|1014517_1016011_-	4-alpha-glucanotransferase	NA	NA	NA	NA
WP_002992583.1\|1016124_1017144_-	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	5.7e-17	27.8
WP_020837249.1\|1017388_1018636_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_020837251.1\|1018909_1020271_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_002984240.1\|1020270_1021107_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_168391419.1\|1021293_1022274_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	3.4e-35	32.3

DBSCAN-SWA_5

1044076 : 1093793

Enterococcus_phage(27.27%)

integrase,tRNA,protease,transposase

attL 1048104:1048123|attR 1089059:1089078

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_180372398.1\|1044076_1045424_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.8e-58	47.5
WP_042361509.1\|1045687_1046560_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_020837283.1\|1046783_1048094_+	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
1048104:1048123	attL	NA	NA	NA	NA
WP_002987505.1\|1048171_1048465_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_009880536.1\|1048559_1048745_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_080147668.1\|1048820_1049018_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	U5P429	Shigella_phage	3.7e-10	49.2
WP_115353187.1\|1049058_1049172_+\|transposase	transposase	NA	NA	NA	NA
WP_042361510.1\|1049188_1049920_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_020837290.1\|1050034_1050400_+	thioesterase family protein	NA	NA	NA	NA
WP_020837291.1\|1050519_1051740_-	MFS transporter	NA	NA	NA	NA
WP_011888813.1\|1052113_1053598_+	DUF1846 domain-containing protein	NA	NA	NA	NA
WP_002984115.1\|1053704_1054106_-	PaaI family thioesterase	NA	NA	NA	NA
WP_020837293.1\|1055007_1056396_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	D0R096	Streptococcus_phage	3.5e-259	98.3
WP_002984109.1\|1056444_1057896_-	LCP family protein	NA	NA	NA	NA
WP_002989310.1\|1058103_1058595_-	shikimate kinase	NA	NA	NA	NA
WP_020837296.1\|1058587_1059871_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_014407653.1\|1059981_1060947_-	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_011054629.1\|1060948_1061809_-	methionyl aminopeptidase	NA	NA	NA	NA
WP_002989302.1\|1061824_1063108_-	CBS domain-containing protein	NA	NA	NA	NA
WP_002984095.1\|1063116_1063659_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_020837299.1\|1064992_1066252_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_011054632.1\|1066425_1067622_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	9.9e-138	65.4
WP_020837301.1\|1068157_1070536_-	leucine-rich repeat domain-containing protein	NA	NA	NA	NA
WP_020837303.1\|1070739_1071681_+	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor	NA	NA	NA	NA
WP_002992607.1\|1071655_1071859_-	DUF3272 domain-containing protein	NA	NA	NA	NA
WP_020837305.1\|1071953_1073624_-	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	6.6e-47	41.1
WP_020837307.1\|1073623_1074121_-	GAF domain-containing protein	NA	NA	NA	NA
WP_020837309.1\|1074265_1075075_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_002989257.1\|1075127_1075391_-	DUF1294 domain-containing protein	NA	NA	NA	NA
WP_042361511.1\|1075470_1076097_-	uridine kinase	A0A1V0SAA3	Catovirus	1.7e-35	39.7
WP_042361512.1\|1076194_1077280_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.7e-33	31.9
WP_020837316.1\|1077389_1078664_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_020837318.1\|1078758_1080186_-	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_020837320.1\|1080370_1082104_-	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
WP_002984031.1\|1082108_1082372_-	phosphocarrier protein HPr	NA	NA	NA	NA
WP_002989242.1\|1082764_1082983_+	redoxin NrdH	A0A249XUR7	Enterococcus_phage	1.1e-13	49.3
WP_020837330.1\|1083002_1085162_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	6.1e-263	63.6
WP_020837332.1\|1085494_1086454_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	3.7e-127	70.5
WP_020837334.1\|1086428_1087742_+	chloride channel protein	NA	NA	NA	NA
WP_002995750.1\|1089126_1089822_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
1089059:1089078	attR	NA	NA	NA	NA
WP_002995753.1\|1089840_1090602_-	DUF3169 family protein	NA	NA	NA	NA
WP_002989220.1\|1090598_1090814_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002995756.1\|1091174_1093793_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.1e-61	34.1

DBSCAN-SWA_6

1102458 : 1169129

Streptococcus_phage(66.67%)

capsid,holin,portal,tail,tRNA,terminase,integrase

attL 1130218:1130237|attR 1166502:1166521

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002995782.1\|1102458_1103487_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_002983986.1\|1103493_1104714_+	DUF3114 domain-containing protein	NA	NA	NA	NA
WP_002995785.1\|1104827_1105418_-	serine hydrolase	NA	NA	NA	NA
WP_002983979.1\|1105642_1105876_-	hypothetical protein	NA	NA	NA	NA
WP_002983977.1\|1106042_1106648_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.8e-58	53.2
WP_020837352.1\|1106744_1107785_-	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_020837354.1\|1107855_1110099_-	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	1.8e-55	59.2
WP_020837356.1\|1110079_1110742_-	ComEA family DNA-binding protein	NA	NA	NA	NA
WP_012560804.1\|1110941_1111682_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_011054662.1\|1111721_1112576_+\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_002989164.1\|1112565_1112844_+	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	1.8e-05	36.0
WP_002994363.1\|1112867_1114868_-	potassium transporter Kup	M1IBC2	Acanthocystis_turfacea_Chlorella_virus	1.3e-65	34.0
WP_002989158.1\|1114994_1116614_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.9e-59	36.5
WP_020837360.1\|1116920_1118465_-	peptide chain release factor 3	A0A1B0RXH7	Streptococcus_phage	1.1e-35	29.1
WP_002994365.1\|1118712_1119408_-	TIGR02206 family membrane protein	NA	NA	NA	NA
WP_002994368.1\|1119511_1120879_-	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_002994369.1\|1121077_1122124_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_002983939.1\|1122224_1122821_-	recombination protein RecR	NA	NA	NA	NA
WP_002989140.1\|1124513_1125056_-	hypothetical protein	NA	NA	NA	NA
WP_002983930.1\|1125216_1125738_-	transcription repressor NadR	NA	NA	NA	NA
WP_002983928.1\|1125844_1126540_-	phosphoglycerate mutase	NA	NA	NA	NA
WP_042361513.1\|1126778_1127714_+	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	1.3e-65	44.8
WP_002989134.1\|1127768_1127942_-	hypothetical protein	NA	NA	NA	NA
WP_020837373.1\|1128013_1129876_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.4e-90	33.8
1130218:1130237	attL	NA	NA	NA	NA
WP_011017964.1\|1130406_1130589_-	hypothetical protein	A3F673	Streptococcus_phage	1.4e-19	76.7
WP_011285611.1\|1130826_1131627_+	streptodornase Sda3	NA	NA	NA	NA
WP_011017966.1\|1131897_1132332_+	hypothetical protein	NA	NA	NA	NA
WP_010922446.1\|1132401_1133607_-	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	5.9e-207	84.3
WP_003058873.1\|1133722_1133950_-\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_002987582.1\|1133946_1134222_-	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_020833519.1\|1134231_1134849_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.5e-76	88.3
WP_020837375.1\|1134851_1135283_-	DUF1617 family protein	Q938J8	Temperate_phage	1.6e-66	92.3
WP_020837377.1\|1135294_1137079_-	hypothetical protein	Q938J9	Temperate_phage	9.7e-97	47.9
WP_020837379.1\|1137093_1138092_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	1.1e-126	70.9
WP_010922451.1\|1138091_1140050_-\|tail	phage tail protein	M1PKG3	Streptococcus_phage	5.3e-96	49.2
WP_010922452.1\|1140046_1140742_-	hypothetical protein	A0A1B1P761	Bacillus_phage	7.6e-05	29.6
WP_010922453.1\|1140738_1143096_-	hypothetical protein	M1NRG5	Streptococcus_phage	6.5e-141	50.6
WP_010922454.1\|1143095_1143467_-	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	2.9e-35	62.4
WP_010922455.1\|1143481_1143745_-	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	1.0e-18	55.8
WP_010922456.1\|1143755_1144349_-\|tail	tail protein	M1PKG8	Streptococcus_phage	3.5e-59	62.5
WP_000573598.1\|1144360_1144696_-	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_010922457.1\|1144696_1144933_-	hypothetical protein	A0A0B5A7G2	Streptococcus_phage	2.5e-21	71.4
WP_011285617.1\|1144925_1145264_-	hypothetical protein	M1PFF8	Streptococcus_phage	2.2e-42	70.3
WP_010922459.1\|1145223_1145646_-	phage Gp19/Gp15/Gp42 family protein	A0A0B5A2F6	Streptococcus_phage	3.7e-47	70.8
WP_010922460.1\|1145655_1145856_-	hypothetical protein	NA	NA	NA	NA
WP_010922461.1\|1145855_1146767_-\|capsid	phage major capsid protein	M1PFL0	Streptococcus_phage	9.9e-114	67.3
WP_010922462.1\|1146791_1147253_-	DUF4355 domain-containing protein	M1Q1L0	Streptococcus_phage	4.5e-38	53.2
WP_011285619.1\|1147333_1148749_-\|terminase	terminase	A0A0B5A091	Streptococcus_phage	2.9e-213	74.2
WP_010922464.1\|1148858_1149125_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	7.3e-33	86.4
WP_015055972.1\|1149117_1149297_-	hypothetical protein	NA	NA	NA	NA
WP_010922466.1\|1149346_1149571_-	hypothetical protein	NA	NA	NA	NA
WP_010922467.1\|1149576_1151070_-	hypothetical protein	M1Q184	Streptococcus_phage	2.0e-87	55.0
WP_020837398.1\|1151062_1152331_-\|portal	phage portal protein	M1PFL4	Streptococcus_phage	8.5e-188	75.4
WP_002994106.1\|1152327_1152684_-	hypothetical protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
WP_010922469.1\|1152832_1153177_-	HNH endonuclease	M1Q0W7	Streptococcus_phage	5.5e-41	68.5
WP_010922470.1\|1153285_1153705_-	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	8.7e-57	79.9
WP_010922070.1\|1153972_1154608_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.0e-89	69.4
WP_002988369.1\|1154609_1154879_-	hypothetical protein	A7J287	Streptococcus_phage	9.6e-25	71.9
WP_002988366.1\|1154962_1155475_-	hypothetical protein	Q708P9	Streptococcus_phage	2.3e-67	78.0
WP_020837403.1\|1155471_1155813_-	hypothetical protein	M1NS23	Streptococcus_phage	1.1e-12	38.7
WP_011285624.1\|1155990_1156158_-	hypothetical protein	A0A1S5SEF3	Streptococcus_phage	3.3e-07	51.9
WP_020837407.1\|1156167_1156965_-	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	4.3e-129	84.2
WP_011285626.1\|1156961_1157891_-	recombinase RecT	M1NRN6	Streptococcus_phage	1.1e-91	72.2
WP_002988359.1\|1157893_1158223_-	hypothetical protein	J7KGX3	Streptococcus_phage	2.1e-45	83.5
WP_011017565.1\|1158278_1158485_-	hypothetical protein	NA	NA	NA	NA
WP_011017992.1\|1158493_1158634_-	hypothetical protein	NA	NA	NA	NA
WP_002985387.1\|1158630_1158864_-	hypothetical protein	Q938N1	Temperate_phage	6.1e-36	94.8
WP_011285627.1\|1158844_1159234_-	DnaD domain protein	Q938N2	Temperate_phage	9.3e-45	81.4
WP_011285628.1\|1159717_1159903_-	hypothetical protein	Q938N3	Temperate_phage	5.8e-21	88.5
WP_002990080.1\|1159904_1160216_-	hypothetical protein	A0A1S5SA25	Streptococcus_phage	4.1e-43	78.4
WP_011054585.1\|1160293_1160479_-	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011284879.1\|1160645_1160885_+	hypothetical protein	NA	NA	NA	NA
WP_011285629.1\|1161026_1161833_+	TIGR02391 family protein	A0A1S5SBU1	Streptococcus_phage	7.9e-123	82.1
WP_010922204.1\|1161767_1162034_-	hypothetical protein	A0A1S5SC19	Streptococcus_phage	1.1e-23	66.3
WP_011285630.1\|1162065_1162782_-	phage antirepressor KilAC domain-containing protein	C9WB91	Streptococcus_virus	6.8e-118	87.7
WP_002993390.1\|1162793_1162985_-	hypothetical protein	A7J270	Streptococcus_phage	4.0e-25	92.1
WP_020837421.1\|1163620_1163716_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_011285631.1\|1164138_1164486_+	helix-turn-helix transcriptional regulator	A0A1S5SEQ8	Streptococcus_phage	3.6e-40	71.8
WP_020837423.1\|1164489_1164870_+	ImmA/IrrE family metallo-endopeptidase	A0A1S5SFH2	Streptococcus_phage	2.3e-40	60.3
WP_011285632.1\|1164881_1165148_+	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_020837425.1\|1165271_1166414_+\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	5.3e-173	77.1
WP_002983920.1\|1166503_1166779_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.6e-25	73.0
1166502:1166521	attR	NA	NA	NA	NA
WP_002989129.1\|1166877_1167465_-	YpmS family protein	NA	NA	NA	NA
WP_002992620.1\|1167442_1168285_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_002983913.1\|1168277_1169129_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	5.4e-13	35.7

DBSCAN-SWA_7

1403394 : 1499041

102

Temperate_phage(48.53%)

capsid,holin,portal,tail,tRNA,terminase,integrase

attL 1454565:1454582|attR 1496118:1496135

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011054945.1\|1403394_1404834_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_020837615.1\|1404833_1406300_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_012560907.1\|1406299_1406602_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_002988559.1\|1407595_1408150_-	cysteine hydrolase	G3MA16	Bacillus_virus	2.6e-24	38.5
WP_002992569.1\|1408296_1409079_-	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_020837616.1\|1409295_1410510_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_002992571.1\|1410740_1411193_+	universal stress protein	NA	NA	NA	NA
WP_002992572.1\|1411315_1412704_-	Cof-type HAD-IIB family hydrolase	A0A0H3UZF4	Geobacillus_virus	2.1e-22	37.1
WP_002992573.1\|1412775_1413741_+	asparaginase	NA	NA	NA	NA
WP_002988556.1\|1414089_1414794_-	ABC transporter permease	NA	NA	NA	NA
WP_002991995.1\|1414806_1415709_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.9e-38	44.2
WP_020837617.1\|1416000_1418016_-	ATP-dependent DNA helicase RecG	NA	NA	NA	NA
WP_020837618.1\|1418390_1419845_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-11	30.5
WP_020837619.1\|1419781_1420462_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_002983234.1\|1420458_1421052_-	MptD family putative ECF transporter S component	NA	NA	NA	NA
WP_042361520.1\|1421048_1422719_-	ABC transporter ATP-binding protein	F2Y165	Organic_Lake_phycodnavirus	7.6e-19	29.6
WP_020837621.1\|1422711_1424475_-	ABC transporter ATP-binding protein/permease	F2Y1V5	Organic_Lake_phycodnavirus	1.3e-21	31.1
WP_002983221.1\|1424471_1425308_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	7.9e-17	27.2
WP_002983218.1\|1425304_1426327_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	2.0e-14	26.2
WP_020837623.1\|1426328_1428071_-	heme ABC transporter substrate-binding protein IsdE	NA	NA	NA	NA
WP_042361521.1\|1428267_1432095_-	heme-binding protein Shr	NA	NA	NA	NA
WP_020837625.1\|1432584_1434096_-	CHAP domain-containing protein	W5R8Q8	Staphylococcus_phage	2.5e-05	41.7
WP_002983202.1\|1434182_1435283_-	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	3.3e-31	31.0
WP_002983199.1\|1435279_1435636_-	holo-ACP synthase	NA	NA	NA	NA
WP_002988523.1\|1435751_1438271_-	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_020837626.1\|1438404_1439358_-	mannose-6-phosphate isomerase, class I	NA	NA	NA	NA
WP_011184899.1\|1439452_1440337_-	ROK family protein	NA	NA	NA	NA
WP_042361522.1\|1440600_1443573_-	endo-beta-N-acetylglucosaminidase	NA	NA	NA	NA
WP_002995059.1\|1443804_1445688_-	PTS beta-glucoside transporter subunit IIBCA	NA	NA	NA	NA
WP_002995062.1\|1445929_1447369_+	glycoside hydrolase family 32 protein	NA	NA	NA	NA
WP_020837630.1\|1447373_1448339_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	1.0e-20	27.7
WP_002988501.1\|1448479_1448932_-	transcription antitermination factor NusB	NA	NA	NA	NA
WP_002993228.1\|1448924_1449314_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002988496.1\|1449359_1449917_-	elongation factor P	NA	NA	NA	NA
WP_020837633.1\|1450012_1450474_-	hypothetical protein	F8WPT6	Bacillus_phage	4.3e-33	54.3
WP_042361523.1\|1450508_1451582_-	aminopeptidase P family protein	A0A0P0I8D7	Acinetobacter_phage	4.6e-17	32.8
WP_002993235.1\|1451697_1454526_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	5.9e-306	55.7
1454565:1454582	attL	NA	NA	NA	NA
WP_011184907.1\|1454752_1454935_-	hypothetical protein	A3F673	Streptococcus_phage	4.4e-21	83.3
WP_011285611.1\|1455172_1455973_+	streptodornase Sda3	NA	NA	NA	NA
WP_011017966.1\|1456244_1456679_+	hypothetical protein	NA	NA	NA	NA
WP_011888701.1\|1456728_1457595_-	DUF334 domain-containing protein	Q938J2	Temperate_phage	1.1e-133	99.7
WP_011017840.1\|1457582_1458107_-	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_020837640.1\|1458246_1459449_-	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	1.1e-237	98.0
WP_003058873.1\|1459564_1459792_-\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_011017397.1\|1459788_1460061_-	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_020837644.1\|1460072_1460690_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	2.9e-77	87.8
WP_011018112.1\|1460692_1461121_-	DUF1617 family protein	Q938J8	Temperate_phage	1.9e-54	78.6
WP_020837647.1\|1461132_1463016_-	gp58-like family protein	Q938J9	Temperate_phage	1.9e-215	87.3
WP_020837648.1\|1463028_1464051_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	3.2e-169	91.7
WP_011054737.1\|1466189_1466906_-\|tail	phage tail family protein	Q938K2	Temperate_phage	2.9e-137	100.0
WP_020837651.1\|1466902_1470163_-	tape measure protein	Q938K3	Temperate_phage	0.0e+00	99.7
WP_020837652.1\|1470152_1470731_-	bacteriophage Gp15 family protein	Q938K4	Temperate_phage	6.5e-103	97.4
WP_010922086.1\|1470734_1471169_-	hypothetical protein	Q938K5	Temperate_phage	2.9e-71	99.3
WP_011054741.1\|1471207_1471693_-	hypothetical protein	Q938K6	Temperate_phage	1.6e-86	100.0
WP_010922084.1\|1471692_1472091_-\|capsid	minor capsid protein	Q79S87	Temperate_phage	3.5e-71	100.0
WP_010922083.1\|1472087_1472444_-\|capsid	minor capsid protein	Q79S88	Temperate_phage	4.5e-62	100.0
WP_010922082.1\|1472443_1472776_-\|capsid	minor capsid protein	Q79S86	Temperate_phage	9.6e-59	100.0
WP_010922081.1\|1472765_1473182_-	hypothetical protein	Q938K7	Temperate_phage	4.3e-56	99.1
WP_010922080.1\|1473235_1474054_-\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	4.0e-146	100.0
WP_011106689.1\|1474057_1474672_-	hypothetical protein	Q938K8	Temperate_phage	1.3e-96	100.0
WP_011054745.1\|1474797_1475064_-	hypothetical protein	Q938K9	Temperate_phage	1.5e-38	100.0
WP_002986829.1\|1475125_1475365_-	hypothetical protein	Q938L0	Temperate_phage	2.8e-36	100.0
WP_011054746.1\|1475336_1476815_-\|capsid	phage minor capsid protein	Q938L1	Temperate_phage	8.2e-275	100.0
WP_002986832.1\|1476819_1478322_-\|portal	phage portal protein	Q938L2	Temperate_phage	5.4e-282	100.0
WP_042361524.1\|1478335_1479547_-\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	1.8e-224	99.5
WP_010922073.1\|1479629_1480106_-	hypothetical protein	Q938L4	Temperate_phage	4.9e-48	68.4
WP_020837660.1\|1480448_1481615_-	ParB N-terminal domain-containing protein	Q708N6	Streptococcus_phage	2.3e-123	53.9
WP_011017574.1\|1481776_1482214_-	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	6.7e-76	97.9
WP_002987493.1\|1482489_1482660_-	hypothetical protein	A0A097PAS8	Streptococcus_pyogenes_phage	2.9e-27	100.0
WP_020837664.1\|1482716_1483073_-	hypothetical protein	A0A141E1Y8	Streptococcus_phage	2.6e-09	47.8
WP_021299463.1\|1483120_1483885_-	site-specific DNA-methyltransferase	A0A1S5SE41	Streptococcus_phage	4.2e-134	92.3
WP_011017571.1\|1483874_1484357_-	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	9.6e-92	98.8
WP_011017570.1\|1484360_1484645_-	hypothetical protein	A3F628	Streptococcus_phage	4.6e-33	79.8
WP_020837669.1\|1484641_1485055_-	hypothetical protein	Q938M1	Temperate_phage	4.9e-36	65.2
WP_002990061.1\|1485051_1485246_-	hypothetical protein	A3F626	Streptococcus_phage	9.7e-11	86.5
WP_010922210.1\|1485232_1485745_-	hypothetical protein	Q708P9	Streptococcus_phage	3.4e-63	73.8
WP_002990067.1\|1485741_1486080_-	hypothetical protein	M1PKX3	Streptococcus_phage	4.0e-12	37.5
WP_020837672.1\|1486255_1487053_-	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	3.4e-126	82.3
WP_010922473.1\|1487045_1487246_-	hypothetical protein	NA	NA	NA	NA
WP_020837674.1\|1487242_1488232_-	recombinase RecT	A0A286QQF5	Streptococcus_phage	7.6e-59	44.4
WP_010922475.1\|1488231_1488564_-	hypothetical protein	J7KGX3	Streptococcus_phage	2.2e-42	78.7
WP_011017565.1\|1488619_1488826_-	hypothetical protein	NA	NA	NA	NA
WP_011017992.1\|1488834_1488975_-	hypothetical protein	NA	NA	NA	NA
WP_002985387.1\|1488971_1489205_-	hypothetical protein	Q938N1	Temperate_phage	6.1e-36	94.8
WP_002988346.1\|1489185_1489599_-	DnaD domain protein	Q938N2	Temperate_phage	2.4e-59	84.7
WP_019418742.1\|1489720_1489978_-	hypothetical protein	A0A141E1D1	Streptococcus_phage	8.9e-12	40.5
WP_002986881.1\|1490071_1490257_-	hypothetical protein	Q938N3	Temperate_phage	1.2e-23	95.1
WP_002988339.1\|1490285_1490543_-	hypothetical protein	NA	NA	NA	NA
WP_011054766.1\|1490788_1491043_-	hypothetical protein	NA	NA	NA	NA
WP_002986887.1\|1491031_1491232_+	KTSC domain-containing protein	A0A1S5S8T9	Streptococcus_phage	6.3e-21	72.3
WP_002986888.1\|1491228_1491378_-	hypothetical protein	Q938N4	Temperate_phage	1.8e-20	100.0
WP_020837677.1\|1491410_1492127_-	phage antirepressor KilAC domain-containing protein	C9WB91	Streptococcus_virus	4.0e-118	87.7
WP_020837679.1\|1492138_1492330_-	hypothetical protein	A7J270	Streptococcus_phage	1.2e-24	90.5
WP_020837683.1\|1492965_1493061_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_011054768.1\|1493479_1493839_+	helix-turn-helix transcriptional regulator	Q938N6	Temperate_phage	1.1e-60	100.0
WP_002986894.1\|1493852_1494233_+	hypothetical protein	Q938N7	Temperate_phage	5.3e-69	100.0
WP_020837688.1\|1494243_1494765_+	hypothetical protein	Q938N8	Temperate_phage	4.0e-67	99.2
WP_020837690.1\|1494883_1496038_+\|integrase	site-specific integrase	Q938N9	Temperate_phage	2.3e-200	96.7
WP_002983147.1\|1496281_1497226_+	magnesium transporter CorA family protein	NA	NA	NA	NA
1496118:1496135	attR	NA	NA	NA	NA
WP_020837692.1\|1497358_1498015_+	DUF1129 domain-containing protein	NA	NA	NA	NA
WP_002983142.1\|1498145_1498385_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_002993238.1\|1498549_1499041_-	single-stranded DNA-binding protein	A0A286QNX2	Streptococcus_phage	1.3e-59	74.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_021807

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection