CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022047	Listeria monocytogenes plasmid unnamed, complete sequence	0 crisprs	csa3	0	0	3	0
NC_021827	Listeria monocytogenes, complete sequence	1 crisprs	DinG,csa3,WYL,cas3,DEDDh,RT	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 5128

uncultured_virus(100.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002307659.1\|563_770_+	hypothetical protein	NA	NA	NA	NA
WP_023558846.1\|790_1387_+	YdhK family protein	NA	NA	NA	NA
WP_023558753.1\|3166_5128_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	4.6e-92	36.1

DBSCAN-SWA_2

8561 : 47733

Streptococcus_phage(22.73%)

transposase,integrase

attL 8507:8524|attR 46980:46997

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
8507:8524	attL	NA	NA	NA	NA
WP_003759224.1\|8561_9242_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.5e-93	69.9
WP_023558764.1\|9301_9805_+\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	6.6e-19	35.9
WP_003726382.1\|9836_10217_+	hypothetical protein	NA	NA	NA	NA
WP_003726381.1\|10449_12567_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.3e-235	62.6
WP_003726380.1\|12563_12923_-	winged helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	5.4e-23	48.2
WP_003725299.1\|13196_13796_-	recombinase family protein	I1ZBD6	Salisaeta_icosahedral_phage	1.8e-15	31.8
WP_003725298.1\|13954_15391_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2H4JGQ6	uncultured_Caudovirales_phage	9.4e-18	24.8
WP_023558766.1\|15383_15764_+	AAA family ATPase	NA	NA	NA	NA
WP_023558770.1\|16867_17791_+	EamA family transporter	NA	NA	NA	NA
WP_023558772.1\|18310_19459_+	alcohol dehydrogenase catalytic domain-containing protein	E3SJ82	Synechococcus_phage	3.1e-11	24.6
WP_106490519.1\|19771_20659_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	1.9e-69	51.6
WP_023558776.1\|20655_20910_-\|transposase	transposase	Q6J1X3	Lactobacillus_phage	9.4e-14	47.6
WP_023558780.1\|21103_21517_+	hypothetical protein	NA	NA	NA	NA
WP_023558782.1\|21560_22127_-	hypothetical protein	NA	NA	NA	NA
WP_023558784.1\|22395_22740_+	hypothetical protein	NA	NA	NA	NA
WP_023558786.1\|22727_24008_+	Y-family DNA polymerase	O64031	Bacillus_phage	1.8e-92	45.1
WP_003728502.1\|24058_24355_-	hypothetical protein	NA	NA	NA	NA
WP_003728501.1\|24332_25307_-	AAA family ATPase	F0PIG8	Enterococcus_phage	2.4e-33	35.0
WP_003728500.1\|26046_27681_+	primase C-terminal domain-containing protein	NA	NA	NA	NA
WP_023558788.1\|27781_27946_+	hypothetical protein	NA	NA	NA	NA
WP_023558793.1\|28397_28985_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.9e-33	41.7
WP_031642142.1\|29076_29832_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.0e-80	62.8
WP_003755396.1\|29842_31069_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	6.2e-135	60.6
WP_171878362.1\|31577_32003_+	hypothetical protein	NA	NA	NA	NA
WP_023558800.1\|32005_32923_+	hypothetical protein	NA	NA	NA	NA
WP_003728492.1\|33287_33527_+	hypothetical protein	NA	NA	NA	NA
WP_012952171.1\|33538_33979_+	hypothetical protein	NA	NA	NA	NA
WP_023558802.1\|33971_35312_+	hypothetical protein	NA	NA	NA	NA
WP_023558804.1\|35322_35685_+	hypothetical protein	NA	NA	NA	NA
WP_023558806.1\|35704_36469_+	Fic family protein	A0A0G3Y4Q5	Ostreid_herpesvirus	2.6e-06	29.4
WP_003728487.1\|36582_37113_+	hypothetical protein	NA	NA	NA	NA
WP_023558808.1\|37149_37485_-	helix-turn-helix transcriptional regulator	A0A139ZPK3	Marinitoga_camini_virus	2.8e-05	35.0
WP_011011011.1\|37658_38057_+	hypothetical protein	NA	NA	NA	NA
WP_012952173.1\|38769_39114_+	TnpV protein	NA	NA	NA	NA
WP_072235488.1\|39155_39563_+	hypothetical protein	H2DE57	Erwinia_phage	1.4e-11	46.0
WP_013315180.1\|40882_41638_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.4e-81	63.2
WP_011011055.1\|41715_42009_-	DUF3116 family protein	NA	NA	NA	NA
WP_011011054.1\|42025_43180_-	cation:proton antiporter	NA	NA	NA	NA
WP_023558820.1\|43326_44565_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	2.3e-121	55.5
WP_031642122.1\|44586_44946_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	1.7e-08	31.7
WP_023558824.1\|44945_45332_-	CrcB family protein	A0A2H4PQR0	Staphylococcus_phage	6.2e-09	34.4
WP_023558827.1\|45343_45979_-	DUF190 domain-containing protein	NA	NA	NA	NA
WP_176723416.1\|46834_47005_+	hypothetical protein	NA	NA	NA	NA
46980:46997	attR	NA	NA	NA	NA
WP_011011045.1\|47052_47733_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	5.5e-93	69.5

DBSCAN-SWA_3

54278 : 54959

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023558842.1\|54278_54959_+	response regulator transcription factor	W8CYM9	Bacillus_phage	4.0e-35	36.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_021827

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CRISPR-Cas detection and classification

Crispr_ID: NC_021827_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021827_1

27522-27676

Unclear

Consensus_repeat	Method
GTCTCTGGCAAAGCAAGTCTTAACTCTTCATCCGTAGGTGGTGGTGGAAA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NC_021827_1

>merge|NC_021827|1|27522-27676|CRISPRCasFinder
GTCTCTGGCAAAGCAAGTCTTAACTCTTCATCCGTAGGTGGTGGTGGAAATTCGAATGAGCTCGGTTCTGATGTAGCAGGAGCATTAAAACCAAGAAGCATCGGTGTCTCTGGCAAAGCAAGTCTTAACTCTTCATCCGTAGGCGGTGGTGGAAA

>NC_021827|1|1|27522-27676|CRISPRCasFinder
GTCTCTGGCAAAGCAAGTCTTAACTCTTCATCCGTAGGTGGTGGTGGAAA	TTCGAATGAGCTCGGTTCTGATGTAGCAGGAGCATTAAAACCAAGAAGCATCGGT
GTCTCTGGCAAAGCAAGTCTTAACTCTTCATCCGTAGGCGGTGGTGGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_021827.1\|WP_003722740.1\|21592_22216_-\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NC_021827.1\|WP_003725737.1\|20918_21503_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NC_021827.1\|WP_003734712.1\|25643_26513_-\|phosphatidylcholine-phospholipase-C	unknown	unknown	gnl\|CDD\|214813
NC_021827.1\|WP_003725738.1\|20251_20812_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NC_021827.1\|WP_003725507.1\|38535_39744_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NC_021827.1\|WP_003725733.1\|25248_25572_-\|DUF5502-family-protein	unknown	unknown	gnl\|CDD\|340321
NC_021827.1\|WP_003722739.1\|22509_23451_+\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|178836
NC_021827.1\|WP_003725735.1\|24269_24602_+\|putative-heavy-metal-binding-protein	unknown	unknown	gnl\|CDD\|179228
NC_021827.1\|WP_003740378.1\|16598_20138_-\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118
NC_021827.1\|WP_003740376.1\|30534_32124_-\|cholesterol-dependent-cytolysin-listeriolysin-O	unknown	unknown	gnl\|CDD\|366559
NC_021827.1\|WP_003722729.1\|33592_34306_+\|listeriolysin-O-transcriptional-regulator-PrfA	unknown	unknown	gnl\|CDD\|223736
NC_021827.1\|WP_003740377.1\|23483_24203_+\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|378033
NC_021827.1\|WP_003740375.1\|32366_33320_+\|phosphatidylinositol-specific-phospholipase-C	unknown	unknown	gnl\|CDD\|176497
NC_021827.1\|WP_003740374.1\|35356_36730_-\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl\|CDD\|184643
NC_021827.1\|WP_003722728.1\|34349_35306_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NC_021827.1\|WP_003725734.1\|24654_25116_-\|YehR-family-lipoprotein	unknown	unknown	gnl\|CDD\|227145
NC_021827.1\|WP_003725730.1\|28667_30200_-\|zinc-metalloproteinase-Mpl	unknown	unknown	gnl\|CDD\|225768
NC_021827.1\|WP_003722726.1\|37116_37425_-\|septation-regulator-SpoVG	unknown	unknown	gnl\|CDD\|237321
NC_021827.1\|WP_003722725.1\|37543_37852_-\|septation-regulator-SpoVG	unknown	unknown	gnl\|CDD\|237321
NC_021827.1\|WP_003722723.1\|39740_40433_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222

Protein	Function_ID	Function_description	E-value
NC_021827.1\|WP_003722740.1\|21592_22216_-\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	2.38585e-63
NC_021827.1\|WP_003725737.1\|20918_21503_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.9401e-09
NC_021827.1\|WP_003734712.1\|25643_26513_-\|phosphatidylcholine-phospholipase-C	gnl\|CDD\|214813	smart00770, Zn_dep_PLPC, Zinc dependent phospholipase C (alpha toxin). This domain conveys a zinc dependent phospholipase C activity (EC 3.1.4.3). It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridium bifermentans, which is involved in haemolysis and cell rupture. It is also found in a lecithinase of Listeria monocytogenes, which is involved in breaking the 2-membrane vacuoles that surround the bacterium. Structure information: PDB 1ca1.	6.38793e-86
NC_021827.1\|WP_003725738.1\|20251_20812_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	1.72721e-108
NC_021827.1\|WP_003725507.1\|38535_39744_-\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	5.06393e-62
NC_021827.1\|WP_003725733.1\|25248_25572_-\|DUF5502-family-protein	gnl\|CDD\|340321	pfam17606, DUF5502, Family of unknown function (DUF5502). This is a family of unknown function found in Listeria.	2.43993e-44
NC_021827.1\|WP_003722739.1\|22509_23451_+\|L-lactate-dehydrogenase	gnl\|CDD\|178836	PRK00066, ldh, L-lactate dehydrogenase; Reviewed.	0
NC_021827.1\|WP_003725735.1\|24269_24602_+\|putative-heavy-metal-binding-protein	gnl\|CDD\|179228	PRK01119, PRK01119, putative heavy metal-binding protein.	8.98192e-61
NC_021827.1\|WP_003740378.1\|16598_20138_-\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NC_021827.1\|WP_003740376.1\|30534_32124_-\|cholesterol-dependent-cytolysin-listeriolysin-O	gnl\|CDD\|366559	pfam01289, Thiol_cytolysin, Thiol-activated cytolysin.	3.16652e-179
NC_021827.1\|WP_003722729.1\|33592_34306_+\|listeriolysin-O-transcriptional-regulator-PrfA	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	9.59942e-12
NC_021827.1\|WP_003740377.1\|23483_24203_+\|DNA-alkylation-repair-protein	gnl\|CDD\|378033	pfam08713, DNA_alkylation, DNA alkylation repair enzyme. Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alpha helical structure.	9.75553e-22
NC_021827.1\|WP_003740375.1\|32366_33320_+\|phosphatidylinositol-specific-phospholipase-C	gnl\|CDD\|176497	cd00137, PI-PLCc, Catalytic domain of prokaryotic and eukaryotic phosphoinositide-specific phospholipase C. This subfamily corresponds to the catalytic domain present in prokaryotic and eukaryotic phosphoinositide-specific phospholipase C (PI-PLC), which is a ubiquitous enzyme catalyzing the cleavage of the sn3-phosphodiester bond in the membrane phosphoinositides (phosphatidylinositol, PI; Phosphatidylinositol-4-phosphate, PIP; phosphatidylinositol 4,5-bisphosphate, PIP2) to yield inositol phosphates (inositol monosphosphate, InsP; inositol diphosphate, InsP2; inositol trisphosphate, InsP3) and diacylglycerol (DAG). The higher eukaryotic PI-PLCs (EC 3.1.4.11) have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains. They play a critical role in most signal transduction pathways, controlling numerous cellular events, such as cell growth, proliferation, excitation and secretion. These PI-PLCs strictly require Ca2+ for their catalytic activity. They display a clear preference towards the hydrolysis of the more highly phosphorylated PI-analogues, PIP2 and PIP, to generate two important second messengers, InsP3 and DAG. InsP3 triggers inflow of calcium from intracellular stores, while DAG, together with calcium, activates protein kinase C, which then phosphorylates other molecules, leading to altered cellular activity. In contrast, bacterial PI-PLCs contain a single catalytic domain. Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. They participate in Ca2+-independent PI metabolism. They are characterized as phosphatidylinositol-specific phospholipase C (EC 4.6.1.13) that selectively hydrolyze PI, not PIP or PIP2. The TIM-barrel type catalytic domain in bacterial PI-PLCs is very similar to the one in eukaryotic PI-PLCs, in which the catalytic domain is assembled from two highly conserved X- and Y-regions split by a divergent linker sequence. The catalytic mechanism of both prokaryotic and eukaryotic PI-PLCs is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This superfamily also includes a distinctly different type of eukaryotic PLC, glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC), an integral membrane protein characterized in the protozoan parasite Trypanosoma brucei. T. brucei GPI-PLC hydrolyzes the GPI-anchor on the variant specific glycoprotein (VSG), releasing dimyristyl glycerol (DMG), which may facilitate the evasion of the protozoan to the host#s immune system. It does not require Ca2+ for its activity and is more closely related to bacterial PI-PLCs, but not mammalian PI-PLCs.	6.72035e-112
NC_021827.1\|WP_003740374.1\|35356_36730_-\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl\|CDD\|184643	PRK14354, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NC_021827.1\|WP_003722728.1\|34349_35306_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NC_021827.1\|WP_003725734.1\|24654_25116_-\|YehR-family-lipoprotein	gnl\|CDD\|227145	COG4808, COG4808, Uncharacterized protein conserved in bacteria [Function unknown].	1.52192e-59
NC_021827.1\|WP_003725730.1\|28667_30200_-\|zinc-metalloproteinase-Mpl	gnl\|CDD\|225768	COG3227, LasB, Zinc metalloprotease (elastase) [Amino acid transport and metabolism].	3.62455e-140
NC_021827.1\|WP_003722726.1\|37116_37425_-\|septation-regulator-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	5.03804e-54
NC_021827.1\|WP_003722725.1\|37543_37852_-\|septation-regulator-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	2.92652e-53
NC_021827.1\|WP_003722723.1\|39740_40433_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	7.27113e-121

>NC_021827.1|WP_003734712.1|25643_26513_-|phosphatidylcholine-phospholipase-C
MKFKKVVLGMCLTASVLVFPVTIKASACCDEYLKPPAAPHDIDSKLPHKLSWSADNPTNTDVNTHYWLFKQAEKILAKDVDHMRANLMNELKNFDKQIAQGIYDADHKNPYYDTSTFLSHFYNPDKDNTYLPGFANAKITGAKYFNQSVADYREGKFDTAFYKLGLAIHYYTDISQPMHANNFTAISYPPGYHCAYENYVDTIKHNYQATEDMVVKRFCSNDVKEWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKKDTVEPTGARLRDSQQTLAGFLEFWSKKTNE
>NC_021827.1|WP_003725733.1|25248_25572_-|DUF5502-family-protein
MYIKGRLIFFFVMFVIALCSVLILLIIKMSVWKEEPFNLSDAKEIECLGSCKIKNTNQKIHFFSIKKNLFEEKGNMAGILNEHERKGADKSIFIVILDDEKGIANEE
>NC_021827.1|WP_003725734.1|24654_25116_-|YehR-family-lipoprotein
MKMLKKGTTVLFVMIMAVMLVACGDKEETKTYSLSQNGVDSKLTYTYKGDKVTKQTAENTMSYASLGVASKEDAEKMLKATSDKFQGIDGLKEKIEYKDDKAIETLEVDYTKISSEDMNKIPGMSSNGDTSKGISMEESAKMLESQGYKEVSK
>NC_021827.1|WP_003725735.1|24269_24602_+|putative-heavy-metal-binding-protein
MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMEQRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEAQDY
>NC_021827.1|WP_003740377.1|23483_24203_+|DNA-alkylation-repair-protein
MLFLLYLIYSRGVTRTITFDQLNTELQALENPNTIKIFRNHGCPDSLDLYGLKIGDLKKIIRREKLTKNHELAVELIESNNSDLIYLGLLAINPDKITTEQIEKWNIIFRETWSQLTFGLASIVSKRDDALLFAKTWIESDYDLTKSMGWQIYSEHINNLPEAEALLQRAKETLQTETNRTRYSMNGFIITCGIYKDDLHEKAMEAAKSVGKVHVNLGNTACKVPDAISYIEKARNRTK
>NC_021827.1|WP_003722739.1|22509_23451_+|L-lactate-dehydrogenase
MKDHQKIILVGDGAVGSSYAFACVNLSIGQEFGIIDIDKDRTIGDAMDLSHAVPFSTPKKIYSANYSDCHDADLVVVTAGTAQKPGETRLDLVNRNIKIMKGIVDEVMASGFDGIFLIASNPVDILTYATWKFSGLPKERVIGSGTSLDTARFRMSIADYLKVDARNVHGYILGEHGDTEFPAWSHTTVGGLPITEWISEDEQGAMDTIFVSVRDAAYEIINKKGATFYGVAAALARITKAILNNENAILPLSVYLDGHYGMNDIYIGAPAVVNRQGVRHIVEMNLNDKEKEQMKNSADTLKKVLDDAMKQID
>NC_021827.1|WP_003722740.1|21592_22216_-|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MATTLEVQKRETTQHSEVTRLRSEGKVPGIIYGYKSENVPVSVDSLELIKAVRDNGRNAVFSVTVDGKKLNVLLHEYQVDPLKDVLVHVDLLAVDMNEEVETDVRVVLVGDAPGVKAGGVLQQIIHDVKVSATPEKLPETIELDISSLEIGDVLTTNDLPENKDYVVQAEEEETVVTVSAPRAEEEPTTTEAPEPEAVHGKDEEPVE
>NC_021827.1|WP_003725737.1|20918_21503_-|GNAT-family-N-acetyltransferase
MLDKSVPHISAIMVNHDATNYPEFHLPEGYSFCFYKDGLEEDWCRLQLETGQVLSMDSIRARFETEFGNEKEKLAKRCVFVEAPNGEIIGTAMLWDGNTFGEMASRIHWVAVLDSHGGKGIAKALLSKILGLNKSSFVYLTTQTGSYQAIYLYQKFGFEKYVGKTPENWKTVNFQEEKEAAWQIIENKIAEHQA
>NC_021827.1|WP_003725738.1|20251_20812_-|aminoacyl-tRNA-hydrolase
MKLIAGLGNPGKKYERTRHNVGFMVVDELSFRHQTPWKKSKFNGMTSEIIVGGEKMILVKPLTFMNASGECIRPLMDYYNIPIEDVVIVYDDLDLPVGKIRLRQKGSAGGHNGMKSIIQHVKTQEFNRIRVGVSRPLKGEVIHYVLGDFPKAEQPDIIAAIQKSADAIEDFAQTPFIEVMNKYNQK
>NC_021827.1|WP_003740378.1|16598_20138_-|transcription-repair-coupling-factor
MKGLQQLIYEQKDIRAVLNALDEKEKAQLVTGLTGSSRALFASVVEGASKRPVVFVTHNLYHAQKLYDDLLSLMDVDRLFLYPADELISSELSISSPELRGQRVEALDFLLSGKPGIVIVPVAGLRKMLPPVSLWKHFNISIVEGEEIDPDVLRQKLVTMGYTMSGMVNTPGEFSVRGGIIDIYPITEEFPIRIELFDTEVDSLRFFDVETQRSTTRVEEFRLLPATEIILDQSYYPDIVKRLEKKMTHTLNELKENEDKQALVENLEEDLEMLRSGVKPDMFFKYIGLAYPDPASLFDYFPKNTAILLDEFGRILETEESLEREEAEWQTETLSRMETVRDVQVSHSFKKLLEANHSPKIYLSLFQKQMASMRVSKTTNIVYKQMQQFHGQMNVLKTELESWHKNNYAVVILAPNLERAEKMQQTLTDYDMESTILKKESDVPKYGMVQFVIGTFQNGFELPLAKVAIISETELFNKKIKKVKKRQKLSNAERIQSYSELKVGDYVVHVNHGIARYVGMETLDINGVHKDYLLLVYQGEDKLFIPVDQLDLVQKYVGAEGKSPRLNKLGGAEWKRVKKKVQASVQDIADDLIKLYAEREAEKGYAFSADDEMQREFEEAFPYQETEDQLRSISEIKKDMERPRPMDRLLVGDVGYGKTEVALRAAFKAIMDGKQVAFLVPTTILAQQHFETMKERFQGFPIEIGLLSRFRTKKQQTETLKGMKNGTVDVVVGTHRLLSKDVEYQDLGLLIVDEEQRFGVTHKEKIKQMRSKIDVLTLTATPIPRTLHMSMLGVRDLSVIETPPANRFPVQTYVAEQNNVLVREAIERELARDGQVYYLYNRVESITQKADEISAMVPDARVATAHGQMGESELESVILSFLEGEFDVLVTTTIIETGVDIPNVNTLFVQDADRMGLSQLYQLRGRVGRWNRIAYAYFMYQKDKILREEAEKRLSAIKEFTELGSGFKIAMRDLSIRGAGNILGAQQHGFIDSVGFDLYSQMLKEAIEAKKPKEEQKQIVPVEIDIQADAYIPEYYITDGRQKIEMYKRFRNIETLSELEDLQSDMIDRFGEYPEEVEYLFTMTELKVHALEVSIESVKQEQNKITMLFSESGTAGIRGDIVMQIIGEFGRMVGVGMEGTQLKITINVQNKPLKEWLYQVKSLAEKLRGAMKERASAEN
>NC_021827.1|WP_003725730.1|28667_30200_-|zinc-metalloproteinase-Mpl
MKSKLICIIMVIAFQAHFNMAVKADSVGEERLRNNIQAKRNPADLKALPDSCEAKDFYKNFKILDMTKDKLGVTHYTLALSSDGYLTDNDEIKVHVTPDNKIAFINGDLQQGQLRITNQIKITEKNAIEKAFEAIGQSEAHVKSYIGNPVKEKEIIINSRTKRLVYNIKLIFAEPEVASWIIQVDAETGAILKKQNMLSEVERADTHKDFQALGKGANRLLQRPLHVMKINDLFYLVDRTHKGLIRTFDLNHKTDASFGKVVSNKTNMFTDPEFSSAVDAHFYASEVYDYYKNVHQLESLDGKGGEIDSFVHYGLNCNNAFWDGREILYGDGDKKNFKPFSCAKTIVGHELTHAVIQYSAGLEYEGQSGALNESFADVFGYFIAPNHWLIGEDVCVRGLRDGRIRSIKDPDKYNQAAHMKDYESLPITEEGDWGGVHFNSGIPNKAAYNTITKLGKEKTEQLYFRALKYYLTKKAQFTDAKKALQQAAKDLYGEDASKKVAEAWEAVGVN
>NC_021827.1|WP_003740376.1|30534_32124_-|cholesterol-dependent-cytolysin-listeriolysin-O
MKKIMLVFITLILVSLPIAQQTEAKDASAFHKENLISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEINYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNSVDNPIE
>NC_021827.1|WP_003740375.1|32366_33320_+|phosphatidylinositol-specific-phospholipase-C
MYKNYLQRTLVLVLCFILCFFTFPLGGKAYSLNNWNKPIKNSVTTKQWMSALPDTTSLAALSIPGTHDTMSYNGDMTWTLTKPLAQTQTMSLYQQLEAGIRYIDIRAKDNLKIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKILLLSENHTKKPLVINSHKYGMQFGASNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLTFTPRQYAAALNNKVEQFVLNLTSEKVRGLGILIMDFPEKQTIKNIIKNNKFN
>NC_021827.1|WP_003722729.1|33592_34306_+|listeriolysin-O-transcriptional-regulator-PrfA
MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDGIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN
>NC_021827.1|WP_003722728.1|34349_35306_-|ribose-phosphate-diphosphokinase
MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNAVRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEESPIEKLVVTNSIALPEEKWIDKMEQLSVAALLGEAIVRVHENASVSSLFE
>NC_021827.1|WP_003740374.1|35356_36730_-|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MSKRYAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDQISTLNVDKVVTIVGHGAEKVQEHLAGKSEFVKQEEQLGTAHAVLQAKAELAGKDGVTLVVCGDTPLIEASTMEALLKYHHEKRAKATILTTVIEDPTGYGRIIRDDLGIVEKIVEHKDATEKEQRISEINTGTYCFDNKALFEALENVSNDNVQGEYYLPDVIKILKDSDEVVAAYRMESFEESLGVNDRIALAEASRLMQRRINENHMRNGVTLVNPENTYIDIDVKIGQDTVIEPGVMLHGETVIGDDCVVTSGSEIVNSVIGERVHVRTSSIFESKVGDDVQIGPYAHLRPESDIHDHVKIGNYVETKKAVVGEGTKLPHFIYMGDAEIGKNVNVGCGSIAVNYDGKNKAKTIIGDNVFVGCNSNLIAPVKVGDRAFIAAGSTITKDVPDDALGIARAKQDNKLGYAKHLNHGK
>NC_021827.1|WP_003722726.1|37116_37425_-|septation-regulator-SpoVG
MQVTDVRLRRVETDGRMRAIASITLDEEFVVHDIRVIDGNNGLFVAMPSKRGVDGEFRDIAHPINSDTRAKIQEVVLAEYERVGEEEATAVTEEESESVSAE
>NC_021827.1|WP_003722725.1|37543_37852_-|septation-regulator-SpoVG
MEITDVRLRRVETDGRMKAISSITIDGEFVIHDIRVIDGNEGLFVAMPSKRTPDGEFRDIAHPINSGTRAKIQEAVLAAYEVADEPAVNEESSADESIVEEN
>NC_021827.1|WP_003725507.1|38535_39744_-|ABC-transporter-permease
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNLITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYKAARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGDPIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGDEKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGIIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
>NC_021827.1|WP_003722723.1|39740_40433_-|ABC-transporter-ATP-binding-protein
MPKPLIDMKNLTKTYTLGGETFKALDDVTFTVEQGEFLSIVGPSGSGKSTLMNMIGCLDVPDEGSYHLDDVDVFKLSDNKLSEIRNKKIGFIFQQFNLLPKLSAFENVELPLIYAGLSVSAREKAAIECLEKVGLLEKRRNLPTQLSGGQQQRVAIARALAGKPQILLADEPTGALDSKTGKEVMGILQELNRAGNTIVMITHDPTIASYGTRSIRIQDGKLFHEEATQA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

104720 : 111247

uncultured_Caudovirales_phage(33.33%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003724951.1\|104720_105539_-\|tail	phage tail family protein	A0A2H4JAE4	uncultured_Caudovirales_phage	1.7e-40	34.9
WP_003731178.1\|105535_107404_-	membrane protein	A0A097PAU2	Streptococcus_pyogenes_phage	3.5e-20	45.8
WP_003740367.1\|107390_107795_-	hypothetical protein	NA	NA	NA	NA
WP_003721745.1\|107836_108139_-	hypothetical protein	NA	NA	NA	NA
WP_003721744.1\|108186_108699_-\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_003728212.1\|108711_109101_-	DUF5072 family protein	NA	NA	NA	NA
WP_003724947.1\|109380_109797_-	hypothetical protein	A8ASQ1	Listeria_phage	1.3e-20	38.6
WP_003724946.1\|109808_110237_-	hypothetical protein	NA	NA	NA	NA
WP_003721740.1\|110453_110789_+	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_003728215.1\|110794_111247_+	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9

DBSCAN-SWA_2

633673 : 641518

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722610.1\|633673_634633_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7
WP_003725411.1\|634752_635736_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	4.0e-52	38.1
WP_003741152.1\|635752_636814_+	galactose mutarotase	NA	NA	NA	NA
WP_003725409.1\|636855_638586_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	9.5e-174	53.1
WP_003722606.1\|638693_639569_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	29.7
WP_003725408.1\|639570_640539_+	YvcK family protein	A1IMD5	Streptococcus_phage	3.9e-68	43.3
WP_003725407.1\|640546_641518_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4

DBSCAN-SWA_3

784577 : 825062

Listeria_phage(91.38%)

tail,plate,terminase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003739618.1\|784577_784925_+	helix-turn-helix transcriptional regulator	A0A0A7RTK4	Clostridium_phage	9.9e-06	40.7
WP_003741076.1\|784979_785456_-	competence protein ComK	NA	NA	NA	NA
WP_020830684.1\|785446_786805_-	recombinase family protein	Q9T193	Listeria_phage	1.8e-252	97.1
WP_003725102.1\|786869_787577_-	hypothetical protein	A0A0B5CTT6	Listeria_phage	4.8e-116	93.6
WP_020830685.1\|787638_788244_-	hypothetical protein	NA	NA	NA	NA
WP_003725101.1\|788258_788477_-	zinc ribbon domain-containing protein	A0A059T6E3	Listeria_phage	2.3e-32	95.8
WP_003725100.1\|788499_788991_-	hypothetical protein	A8ATX4	Listeria_phage	7.0e-90	98.2
WP_003725099.1\|789021_789330_-	helix-turn-helix transcriptional regulator	A8ATX5	Listeria_phage	1.6e-47	99.0
WP_003725098.1\|789478_789748_+	helix-turn-helix transcriptional regulator	A8ATX6	Listeria_phage	3.9e-34	86.5
WP_003725144.1\|789752_789938_+	hypothetical protein	NA	NA	NA	NA
WP_020830686.1\|789897_790161_-	hypothetical protein	NA	NA	NA	NA
WP_003725140.1\|790175_790409_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003741072.1\|790555_790774_+	helix-turn-helix transcriptional regulator	A0A1U9WQN6	Geobacillus_phage	1.2e-06	44.0
WP_003725096.1\|790777_790954_+	hypothetical protein	Q9T184	Listeria_phage	3.7e-09	98.3
WP_003725143.1\|790970_791273_+	hypothetical protein	NA	NA	NA	NA
WP_003733687.1\|791446_791641_+	hypothetical protein	A0A059T6E5	Listeria_phage	1.4e-25	95.3
WP_003733634.1\|791652_791889_+	hypothetical protein	A0A059T5E9	Listeria_phage	3.3e-37	100.0
WP_003727747.1\|791885_792167_+	hypothetical protein	A0A0B5CTX3	Listeria_phage	1.0e-40	100.0
WP_003727748.1\|792198_792360_+	hypothetical protein	A0A059T7X7	Listeria_phage	1.2e-19	98.1
WP_003727749.1\|792352_792595_-	hypothetical protein	A0A059T7Q3	Listeria_phage	1.8e-38	100.0
WP_020830688.1\|792658_793435_+	phage antirepressor KilAC domain-containing protein	A0A0B5D0I2	Listeria_phage	1.1e-142	100.0
WP_020830689.1\|793556_794087_+	hypothetical protein	A8ATY1	Listeria_phage	1.9e-77	86.7
WP_020830690.1\|794076_794283_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003727753.1\|794385_794574_+	hypothetical protein	A0A0B5CU43	Listeria_phage	1.0e-28	98.4
WP_003740962.1\|794806_795766_+	YqaJ viral recombinase family protein	A8ATY5	Listeria_phage	1.3e-177	98.7
WP_003740960.1\|795765_796581_+	recombinase RecT	A0A0B5CTU3	Listeria_phage	1.3e-149	98.9
WP_003740958.1\|796610_797525_+	hypothetical protein	I1W658	Staphylococcus_phage	5.1e-17	39.3
WP_003725084.1\|797521_797794_+	hypothetical protein	A0A059T6G3	Listeria_phage	3.6e-35	91.6
WP_003725083.1\|797790_798351_+	DUF1642 domain-containing protein	A8ATD8	Listeria_phage	9.2e-70	72.0
WP_003725137.1\|798347_798554_+	hypothetical protein	NA	NA	NA	NA
WP_003725082.1\|798540_798924_+	hypothetical protein	D2IZL0	Enterococcus_phage	2.3e-19	66.7
WP_003725081.1\|798927_799116_+	SAM--benzoic acid carboxyl methyltransferase	D7RWG4	Brochothrix_phage	4.4e-08	49.1
WP_020830692.1\|799333_799735_+	hypothetical protein	A0A059T6C9	Listeria_phage	1.9e-53	76.7
WP_020830693.1\|799731_800010_+	hypothetical protein	NA	NA	NA	NA
WP_020830694.1\|800009_800492_+	single-stranded DNA-binding protein	A8ATZ7	Listeria_phage	1.1e-76	92.5
WP_003727772.1\|800511_800694_+	hypothetical protein	A8ASP6	Listeria_phage	8.5e-17	79.4
WP_041197789.1\|800638_801043_+	DUF1064 domain-containing protein	A8ASP7	Listeria_phage	9.9e-58	85.8
WP_020830696.1\|801046_801460_+	DUF2481 family protein	A8ASP8	Listeria_phage	1.6e-18	44.2
WP_003722548.1\|801478_801634_+	hypothetical protein	A0A0B5D186	Listeria_phage	3.3e-22	96.1
WP_020830697.1\|801721_802294_+	sigma-70 family RNA polymerase sigma factor	A0A0B5D145	Listeria_phage	1.3e-90	88.4
WP_003740921.1\|802564_802792_+	hypothetical protein	A8AU06	Listeria_phage	6.8e-32	93.3
WP_003740918.1\|802831_803572_+	hypothetical protein	A0A0B5CTX0	Listeria_phage	1.2e-133	98.8
WP_043993229.1\|803537_804884_+\|terminase	PBSX family phage terminase large subunit	A0A0B5CYJ6	Listeria_phage	2.9e-263	99.1
WP_003740896.1\|804898_806455_+	hypothetical protein	A8ATU7	Listeria_phage	4.8e-294	96.7
WP_003725070.1\|806459_807503_+	hypothetical protein	A0A0B5D111	Listeria_phage	4.8e-197	98.0
WP_003740894.1\|807597_808152_+	hypothetical protein	A8ATU9	Listeria_phage	1.7e-84	89.1
WP_003740892.1\|808174_809047_+	hypothetical protein	A0A0B5CTX8	Listeria_phage	7.4e-159	97.2
WP_003723786.1\|809060_809216_+	hypothetical protein	A0A0B5CYK6	Listeria_phage	1.0e-18	98.0
WP_003740890.1\|809216_809570_+	hypothetical protein	A8ATV2	Listeria_phage	2.4e-60	98.3
WP_003740888.1\|809569_809935_+	hypothetical protein	A8ATV3	Listeria_phage	2.7e-62	95.0
WP_003740887.1\|809924_810242_+	HK97 gp10 family phage protein	A8ATV4	Listeria_phage	1.6e-47	91.4
WP_003740885.1\|810238_810643_+	hypothetical protein	A8ATV5	Listeria_phage	1.2e-63	99.2
WP_003723782.1\|810614_811046_+	Ig domain-containing protein	A0A0B5CYK8	Listeria_phage	8.1e-58	82.9
WP_041197790.1\|811068_811308_+	Ig-like domain-containing protein	A8ASK3	Listeria_phage	4.0e-30	88.6
WP_020830700.1\|811356_811788_+	hypothetical protein	A8ATV7	Listeria_phage	7.8e-69	94.4
WP_041197791.1\|811820_812096_+	hypothetical protein	A0A0B5D116	Listeria_phage	2.2e-40	94.5
WP_023558327.1\|812100_816903_+\|tail	phage tail tape measure protein	A0A0B5CTS6	Listeria_phage	0.0e+00	87.0
WP_003740856.1\|816906_817731_+\|tail	phage tail family protein	A0A0B5CTY7	Listeria_phage	8.6e-157	98.9
WP_003740854.1\|817743_818757_+\|tail	phage tail protein	A0A0B5CYL4	Listeria_phage	1.2e-187	100.0
WP_010991151.1\|818753_819782_+	hypothetical protein	A0A0B5D0C2	Listeria_phage	2.2e-194	100.0
WP_003740845.1\|819778_820852_+\|plate	BppU family phage baseplate upper protein	A0A0B5D119	Listeria_phage	2.5e-196	100.0
WP_003725055.1\|820848_821190_+	hypothetical protein	A8ASL1	Listeria_phage	4.2e-57	100.0
WP_003740843.1\|821190_821337_+	XkdX family protein	A0A0B5CYN8	Listeria_phage	1.5e-19	100.0
WP_003733957.1\|821377_821683_+	hypothetical protein	A0A059T5E6	Listeria_phage	1.8e-43	100.0
WP_020830702.1\|821682_821964_+\|holin	phage holin	A0A059T664	Listeria_phage	5.1e-45	98.9
WP_003740832.1\|821963_822833_+	N-acetylmuramoyl-L-alanine amidase family protein	A8ASL5	Listeria_phage	7.1e-170	98.3
WP_003725050.1\|822956_823757_+	hypothetical protein	NA	NA	NA	NA
WP_003725049.1\|823758_824583_+	DUF3037 domain-containing protein	NA	NA	NA	NA
WP_003725136.1\|824828_825062_+	hypothetical protein	A8ATC5	Listeria_phage	1.2e-34	92.2

DBSCAN-SWA_4

1357100 : 1365386

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003726215.1\|1357100_1358393_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0
WP_003726214.1\|1358473_1359187_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	2.0e-40	38.3
WP_003726213.1\|1359198_1359444_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003726212.1\|1359447_1360131_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003726211.1\|1360123_1362343_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.5e-158	40.7
WP_003722245.1\|1362327_1363755_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_003726210.1\|1363773_1364823_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.2e-63	44.4
WP_003726209.1\|1364819_1365386_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	8.3e-26	36.4

DBSCAN-SWA_5

1854744 : 1913344

Streptococcus_phage(16.67%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003726416.1\|1854744_1856451_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_003726415.1\|1856491_1857754_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_003726414.1\|1857767_1858910_-	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_003727496.1\|1858924_1859713_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_031642179.1\|1859726_1860485_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	3.3e-22	42.1
WP_003723450.1\|1860715_1861273_-	ribosome recycling factor	NA	NA	NA	NA
WP_003723449.1\|1861272_1862001_-	UMP kinase	NA	NA	NA	NA
WP_003726672.1\|1862293_1862668_+	hypothetical protein	NA	NA	NA	NA
WP_012681273.1\|1862645_1863851_+	helicase SNF2	L0P6E9	Lactobacillus_phage	7.0e-91	46.6
WP_003726670.1\|1863840_1865145_+	DUF3440 domain-containing protein	A0A220GKF8	Streptococcus_phage	4.7e-133	51.9
WP_003726669.1\|1865154_1865661_+	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	1.4e-56	66.7
WP_003726668.1\|1865682_1866414_+	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	2.3e-81	58.0
WP_003726667.1\|1866462_1866702_-	YneF family protein	NA	NA	NA	NA
WP_003734516.1\|1866922_1868917_-	transketolase	NA	NA	NA	NA
WP_003726567.1\|1869063_1869291_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003726566.1\|1869384_1869714_-	cell division suppressor protein YneA	NA	NA	NA	NA
WP_003723438.1\|1869870_1870485_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	9.3e-15	62.1
WP_003726565.1\|1870515_1871040_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003726564.1\|1871073_1872369_-	arsenic transporter	A0A2H4PQU3	Staphylococcus_phage	2.5e-147	62.6
WP_003723435.1\|1872512_1873847_-	type I glutamate--ammonia ligase	A0A1V0SJ53	Klosneuvirus	2.0e-06	26.4
WP_003719570.1\|1873917_1874286_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003727505.1\|1874487_1875714_-	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_012681271.1\|1875706_1876930_-	GTPase HflX	NA	NA	NA	NA
WP_003719566.1\|1877040_1877274_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_003726658.1\|1877395_1878313_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003723738.1\|1878439_1880116_-	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_003726657.1\|1880348_1881047_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	6.4e-12	31.9
WP_003734520.1\|1881259_1883146_+	peptidoglycan O-acetyltransferase OatA	B5WZU0	Pseudomonas_phage	2.9e-43	32.2
WP_020830742.1\|1883178_1884999_-	class 1 internalin InlK	NA	NA	NA	NA
WP_003726814.1\|1885625_1886093_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_020830743.1\|1886176_1888636_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	8.1e-102	31.6
WP_003727510.1\|1888632_1890600_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.1e-123	42.5
WP_003726699.1\|1890780_1891188_-	CoA-binding protein	NA	NA	NA	NA
WP_003726698.1\|1891345_1891942_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003726697.1\|1891983_1892856_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_003724130.1\|1892858_1893170_-	hypothetical protein	NA	NA	NA	NA
WP_003726696.1\|1893192_1893612_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003726695.1\|1893715_1894495_-	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_003727514.1\|1894515_1895925_-\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	7.5e-44	27.8
WP_003724001.1\|1895938_1896478_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_003731303.1\|1896498_1897401_-	tyrosine recombinase XerC	A0A142K7N4	Mycobacterium_phage	1.8e-14	29.5
WP_003726401.1\|1897683_1898988_-\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_003727517.1\|1899050_1901129_-	type I DNA topoisomerase	A0A1V0SB35	Catovirus	5.4e-107	37.5
WP_003727518.1\|1901401_1902262_-	DNA-protecting protein DprA	NA	NA	NA	NA
WP_003727519.1\|1902395_1903181_-	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	6.7e-26	37.6
WP_003726396.1\|1903177_1904041_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003727520.1\|1904050_1904593_-	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003726394.1\|1904694_1905264_-	type I signal peptidase SipY	NA	NA	NA	NA
WP_003726393.1\|1905298_1905865_-	type I signal peptidase SipX	NA	NA	NA	NA
WP_003723886.1\|1905983_1907243_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_003723884.1\|1907427_1908711_-	trigger factor	NA	NA	NA	NA
WP_003727521.1\|1908825_1909764_-	hypothetical protein	NA	NA	NA	NA
WP_003731300.1\|1910025_1910691_-	hypothetical protein	NA	NA	NA	NA
WP_003727523.1\|1910706_1911240_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003727524.1\|1911363_1911579_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003723563.1\|1911729_1912125_+	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003734523.1\|1912204_1913344_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_6

2064367 : 2071293

Clostridium_phage(33.33%)

integrase

attL 2060568:2060581|attR 2065754:2065767

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2060568:2060581	attL	NA	NA	NA	NA
WP_003740555.1\|2064367_2065441_-\|integrase	site-specific integrase	A0A0A8WF08	Clostridium_phage	5.5e-87	46.5
WP_003724638.1\|2065443_2065641_-	LysR family transcriptional regulator	Q8SBM7	Clostridium_phage	1.5e-06	46.3
WP_003724637.1\|2065818_2066298_+	helix-turn-helix transcriptional regulator	A0A2H4JDE4	uncultured_Caudovirales_phage	7.3e-07	34.3
2065754:2065767	attR	NA	NA	NA	NA
WP_012681222.1\|2066496_2068053_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	2.3e-17	28.1
WP_003724635.1\|2068181_2068586_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_003724634.1\|2068645_2068954_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_003727000.1\|2068966_2069791_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	9.7e-68	52.6
WP_003724632.1\|2069802_2071293_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	2.8e-113	49.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022047

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_021827

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection