CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_021884	Burkholderia pseudomallei MSHR305 chromosome 1, complete sequence	2 crisprs	DinG,DEDDh,WYL,cas3,csa3	0	0	9	0
NC_021877	Burkholderia pseudomallei MSHR305 chromosome 2, complete sequence	2 crisprs	csa3,cas3,RT	1	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_021884_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021884_1

906583-906724

Orphan

Consensus_repeat	Method
CGCCGGCGTTCGCCGCATACGCGGCAGACGCCGTTCCTGCGCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021884_1

>merge|NC_021884|1|906583-906724|CRISPRCasFinder
CGCCGGCGTTCGCCGCATACGCGGCAGACGCCGTTCCTGCGCGAGCCGCTGCGAACTTGCGAACGGCATTTCGTCCGCCACCGCTTCAACGCTTGGCACGCCGGCGTTCGCCGCATACGCGGCAGACGCCGTTCCAGCGCGA

>NC_021884|1|1|906583-906724|CRISPRCasFinder
CGCCGGCGTTCGCCGCATACGCGGCAGACGCCGTTCCTGCGCGA	GCCGCTGCGAACTTGCGAACGGCATTTCGTCCGCCACCGCTTCAACGCTTGGCA
CGCCGGCGTTCGCCGCATACGCGGCAGACGCCGTTCCAGCGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_021884.1\|WP_004534949.1\|905403_906336_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NC_021884.1\|WP_004543011.1\|899239_900364_-\|cytochrome-b/b6-domain-containing-protein	unknown	unknown	gnl\|CDD\|226602
NC_021884.1\|WP_004521865.1\|902289_904221_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NC_021884.1\|WP_004193339.1\|901339_901645_-\|pentapeptide-MXKDX-repeat-protein	unknown	unknown	gnl\|CDD\|131998
NC_021884.1\|WP_160974052.1\|897996_898209_-\|hypothetical-protein	unknown	unknown	unknown
NC_021884.1\|WP_004542979.1\|898432_899224_-\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239026
NC_021884.1\|WP_004542975.1\|904908_905133_+\|hypothetical-protein	unknown	unknown	unknown
NC_021884.1\|WP_004543005.1\|909486_912183_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|236783
NC_021884.1\|WP_004193167.1\|923811_923991_-\|hypothetical-protein	unknown	unknown	unknown
NC_021884.1\|WP_004542994.1\|924230_925286_+\|Fe(3+)-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270260
NC_021884.1\|WP_004192878.1\|922097_922289_+\|hypothetical-protein	unknown	unknown	unknown
NC_021884.1\|WP_004195184.1\|900354_901179_-\|DUF1223-domain-containing-protein	unknown	unknown	gnl\|CDD\|369071
NC_021884.1\|WP_004193128.1\|904444_904657_+\|glycine-zipper-2TM-domain-containing-protein	unknown	unknown	gnl\|CDD\|182532
NC_021884.1\|WP_041188564.1\|907400_908684_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NC_021884.1\|WP_004193488.1\|909085_909490_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|181730
NC_021884.1\|WP_004534567.1\|919824_922101_+\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|372320
NC_021884.1\|WP_004521870.1\|915988_919333_-\|exodeoxyribonuclease-V-subunit-gamma	unknown	unknown	gnl\|CDD\|335690
NC_021884.1\|WP_004543008.1\|912179_915992_-\|exodeoxyribonuclease-V-subunit-beta	unknown	unknown	gnl\|CDD\|236784
NC_021884.1\|WP_004192513.1\|922285_923650_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182566
NC_021884.1\|WP_004542991.1\|897057_897993_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|183067

Protein	Function_ID	Function_description	E-value
NC_021884.1\|WP_004534949.1\|905403_906336_+\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.49752e-12
NC_021884.1\|WP_004543011.1\|899239_900364_-\|cytochrome-b/b6-domain-containing-protein	gnl\|CDD\|226602	COG4117, COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion].	1.02141e-55
NC_021884.1\|WP_004521865.1\|902289_904221_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NC_021884.1\|WP_004193339.1\|901339_901645_-\|pentapeptide-MXKDX-repeat-protein	gnl\|CDD\|131998	TIGR02953, conserved_hypothetical_protein, pentapeptide MXKDX repeat protein. Members of this protein family are small bacterial proteins, each with an N-terminal signal sequence followed by up to 11 imperfect repeats of a pentapeptide. The pentapeptide repeat usually follows the form Met-Xaa-Lys-Asp-Xaa.	0.000353246
NC_021884.1\|WP_004542979.1\|898432_899224_-\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239026	cd02108, bact_SO_family_Moco, bacterial subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. This domain is found in a variety of oxidoreductases. Common features of all known members of this family, like sulfite oxidase and nitrite reductase, are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate. The specific function of this subgroup is unknown.	6.54795e-91
NC_021884.1\|WP_004543005.1\|909486_912183_-\|AAA-family-ATPase	gnl\|CDD\|236783	PRK10875, recD, exodeoxyribonuclease V subunit alpha.	2.03735e-72
NC_021884.1\|WP_004542994.1\|924230_925286_+\|Fe(3+)-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270260	cd13542, PBP2_FutA1_ilke, Substrate binding domain of ferric iron-binding protein, a member of the type 2 periplasmic binding fold superfamily. FutA1 is the periplasmic component of an ABC-type iron transporter and serves as the primary receptor in Synerchosystis species. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria and is critical for survival of these pathogens within the host. After binding iron with high affinity, FutA1 interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The iron- and thiamine-binding proteins belong to the PBPI2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.05382e-153
NC_021884.1\|WP_004195184.1\|900354_901179_-\|DUF1223-domain-containing-protein	gnl\|CDD\|369071	pfam06764, DUF1223, Protein of unknown function (DUF1223). This family consists of several hypothetical proteins of around 250 residues in length which are found in both plants and bacteria. The function of this family is unknown. Structurally it lies in the Thioredoxin-like superfamily.	3.14399e-68
NC_021884.1\|WP_004193128.1\|904444_904657_+\|glycine-zipper-2TM-domain-containing-protein	gnl\|CDD\|182532	PRK10540, PRK10540, osmotically-inducible lipoprotein OsmB.	5.81885e-06
NC_021884.1\|WP_041188564.1\|907400_908684_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	3.3191e-53
NC_021884.1\|WP_004193488.1\|909085_909490_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	3.43394e-65
NC_021884.1\|WP_004534567.1\|919824_922101_+\|FUSC-family-protein	gnl\|CDD\|372320	pfam12805, FUSC-like, FUSC-like inner membrane protein yccS. This family has similarities to the fusaric acid resistance protein family. The proteins are lodged in the inner membrane.	5.92051e-82
NC_021884.1\|WP_004521870.1\|915988_919333_-\|exodeoxyribonuclease-V-subunit-gamma	gnl\|CDD\|335690	pfam04257, Exonuc_V_gamma, Exodeoxyribonuclease V, gamma subunit. The Exodeoxyribonuclease V enzyme is a multi-subunit enzyme comprised of the proteins RecB, RecC (this family) and RecD. This enzyme plays an important role in homologous genetic recombination, repair of double strand DNA breaks resistance to UV irradiation and chemical DNA-damage. The enzyme (EC:3.1.11.5) catalyzes ssDNA or dsDNA-dependent ATP hydrolysis, hydrolysis of ssDNA or dsDNA and unwinding of dsDNA. This family consists of two AAA domains.	0
NC_021884.1\|WP_004543008.1\|912179_915992_-\|exodeoxyribonuclease-V-subunit-beta	gnl\|CDD\|236784	PRK10876, recB, exonuclease V subunit beta; Provisional.	0
NC_021884.1\|WP_004192513.1\|922285_923650_+\|amino-acid-permease	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0
NC_021884.1\|WP_004542991.1\|897057_897993_-\|EamA-family-transporter	gnl\|CDD\|183067	PRK11272, PRK11272, putative DMT superfamily transporter inner membrane protein; Provisional.	8.41633e-57

>NC_021884.1|WP_004534949.1|905403_906336_+|DMT-family-transporter
MNLKNALLLIVLAALWGASFLFIRVGVAEFGVAPLMALRVGIGALFLVALMLTRYAPRELIALLRQHAWPLFVVGLLNSAAPFCLFAFAELTLSAGVTSVINATTPLWGALVAYLWLKDSLSLPRALGLVIGFAGVLTLVWDQVFSPHGANPASPATAALAAAAALGATLLYGIAANFTKRKLTGVDPLVSATGSMVGATILLLPFALATWPAAPVSAHAWGSVLALGIACTGVAYFIFFHLIAHIGPARAITVTFVIPVFGILWGALFLGERVSFAMLEGCVIVLLGTALATGAIRRIPGVRPQRNEAA
>NC_021884.1|WP_004542975.1|904908_905133_+|hypothetical-protein
MNKTLVAAALASVALAGCYYPYGYYPASGYYAVPVQTAPVYVAPAYPAYYYPAPSLSLNFGYWSGGGRGYWRHH
>NC_021884.1|WP_004193128.1|904444_904657_+|glycine-zipper-2TM-domain-containing-protein
MKSIRRIGVCAMLIATMASLSACDTMTTRQRNAAIGAGIGGVAGAAIGGNALSTIGGAAAGGLVGSQVGK
>NC_021884.1|WP_004521865.1|902289_904221_+|phosphomethylpyrimidine-synthase-ThiC
MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLAGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ
>NC_021884.1|WP_004193339.1|901339_901645_-|pentapeptide-MXKDX-repeat-protein
MKRNLIAFACVAGFALAAPFAHAQNDAMSKDGMGMSKDAMSKGAMSGDAMSKDAMSKDAMSKDRMGKRHDHMAKGGMKAGPMSKDAMKEPMSSDKMSPMSN
>NC_021884.1|WP_004195184.1|900354_901179_-|DUF1223-domain-containing-protein
MSTDMSISFSVSLRAVAAALSLAAAGAAQAAADGACMARSPDGRQALVELYTSEGCSSCPPADDWLARLAARRAALRVVPLALHVDYWDGLGWADRFAQHRFTERQHALAARGGGRFVYTPEVAVDGRELRDWRDADAFGRRVVATAAEPARVGIALAAKRRAGALDVALSVTPRVGAPRALDAYLALYENGVESQVRAGENRGATLRHERVVRQWIGPLAATADAHASLDVRRALPLPANLRAADAARYGVAAFVEDPATGDVLQALDLPLCG
>NC_021884.1|WP_004543011.1|899239_900364_-|cytochrome-b/b6-domain-containing-protein
MRLNDARAIDQRTRVSPMSATPTTSASTTAMAGARASGAADAPARAPTGADVDAGATAWADATANATANATTDPTIDATADATTDAMANVTTDAATRVTANPPIHETANVPASTAAAATTEAVADARTGTALDAAHPGATQTMSQTMAQTMTQAGTEAASPAGTDAAASGACITRATRARRPIHPLWVRASHWLNALAAVTMALSGWRIYNASPIYAGFVFPRGATLGGWLGGALQWHFAAMWLLFFNGVFYLTMGVATRRFTRKLLPLSASGVARDLRDALRGRLSHDDLSVYNALQRAAYVAAIADLALLVLSGLVIWKSVQFPLLREWFGGYDRARVVHFWAMAFLVAFFVVHVAMAALVPRSLLAMLRGH
>NC_021884.1|WP_004542979.1|898432_899224_-|molybdopterin-dependent-oxidoreductase
MAENDRKKRENDIARIDRASLLIDVRKSLALPSRRLFGKRMLTLGGLAMLTGCTLRDDASADDFLEKVSRANDRVQAWLFGPTRLAPTYAEADITRPFPFNAFYGIDDVPRVDADGFRLAVSGLVTGQRSWSLPALYALPHAEQITRHICVEGWSAIGRWGGTPFREFLRRVGADTSAKYVGFKCADDYYESIDMATALHPQTLLAFEYDGKRLPPEYGFPMKLRMPTKLGYKNPKHIVEIFVTNAYPGGYWVDQGYNWFGGS
>NC_021884.1|WP_160974052.1|897996_898209_-|hypothetical-protein
MLTKCGRHAAHVIIRVRLRVRSSPSVMFAAARSDLSFRTPPFPVIPVFPAPLAGGRIARRSTARRFTRAG
>NC_021884.1|WP_004542991.1|897057_897993_-|EamA-family-transporter
MTPFDRFLAFVARHPPRLPQSRSGRVALALVFIYFAWGSTYLALHVALESFPPLLLSGLRNLLAGVGLFVFAMRRRPVRPTLVEIRNAALVGTMLVTMSSGLIALGMRTVSSGSAAVMVATVPLFATVIASVAGRRVTGGEWGAVALGMVGIVVLNSGGPSSPGSTLGSITVLAGALFWAGGAHLAARLALPHDLFLSTALQIGLGGAASTCIAWVLGERIGHVAWVPGAAFVYLMLAGTMAAYVAYGYLIRHTSPIIASSCMYVNPVVAVALGALLLGEPVTAATVIATIAILGSVGLSFVFDPARWRAQ
>NC_021884.1|WP_041188564.1|907400_908684_+|EAL-domain-containing-protein
MPKTQGFSPESLISQFTRCDAGWCVRYHDVTLASAFQPVISITHKRVVGYEALARATDANGAPISPDTLFARAQARGETILLDRLTRCLHVANFAAQDTGACWLFLNVLPQMFDAGISPGAFIEALCAHFALPPTRVVLEVIEQPSRNEVALARTIDMIQHGDFLIAVDDFGTGFSNFDRIWQIKPDIVKLDRSILERSLAASDAHRIIHHLVTMLHHAGTMVLAEGVENEDALQILMDADVDFVQGFCFGRPAPSLEHARRAAPARIEAAWRRFAERTKARCGDVVHPGFDTIERIMLTGAADYAQTRNLRDAAQRLLTSPIVRRVFVAEANGEQVEPSVAIETPEAPSATARRLAPLLPELHCNWSRRAYFQRAIAAPGRVALMGPHFSLTDGRDCYTAAVAIHLGTTLKVFCVDFDFSSYGDGR
>NC_021884.1|WP_004193488.1|909085_909490_-|aminoacyl-tRNA-hydrolase
MTLRYAFSPDEVELTAVRAQGAGGQNVNKVSSAIHLRFDIRASSLPDDVKARLFARADQRITREGVIVIKAQEYRTQEKNRAAALARLDTLIRSAGVTPRKRVATRPTRASKERRLAEKGRRSEVKSGRGRVVE
>NC_021884.1|WP_004543005.1|909486_912183_-|AAA-family-ATPase
MSVVDERFAWTGGLADRLPEPADFGLALAEGFARRIGMLSRRVGASAAAARWAARAAFAASRATAAGHVCVALRALAQRYDEPYDDVRAALAASGVTAFDGIVRGGECPLVVDRDGRLYLARYFEYETRLANALVERSRCGGAPAGGADALSPDALGERLVRYFGPQKERGVDWQRVAALIALTGRVTIVSGGPGTGKTTTVVGVIACLLDAHPELRIALAAPTGKAAQRMQEALHARAGSLPAELAARLPRTSCTLHRLLGGGPGGRFAHHRDNPLPYDLVVVDEASMIDVALAAHLLDALAPNARLVLLGDKDQLAAVEAGAVFAELSARPAFSPATCATIARALGVGEAEFVAALPDGFVVQAAGAERVADARAAAADMDAAARGTAGAAAAAARATAAAAARMTTAAAAARGAAPESAAQRAPAPHAGRRGGGRASNRTVDDAQGSLFAFDDDAFGVGTSGGEPGAGAQGAGRRDGGAPSLDGPHAGHRDGGASPGVAHSRRDAFDARARSGPADVSDVENAARAYAPAGAAGPADSPADASFVEPAAWIEADELAWLDNAVFSFSEGASANAEADGRRSAAATATDAGARTAPPVAREATAPTPRETARSDGSAVAPLTDCVVWLERNYRFGLDSPIGRLSLAIRRGAVQDALDALSTQDDAAARFSDDGGATLSAATVEQLARGFAGYAAALRDALATPEPDALPLFDVLNRFRVLCATRTGARGAEEVNARMAAEVRRAVRVPLALGAHWFAGRPVMVTRNDYALGLFNGDIGIALPGARGALRVWFRGADGRARAVSPAALPPHDTAFALTVHKSQGSEFDDAALILPASFNRVLSRELVYTAITRARARVQVIGSRAVLALAIATRTARDSGLAARIADALRARQEGAR
>NC_021884.1|WP_004543008.1|912179_915992_-|exodeoxyribonuclease-V-subunit-beta
MSHVAPSGPSASELDVFACPLDGVNQIEASAGTGKTWNICALYVRLLLEKDLGADEILVVTFTKAATAELHERIRARLAQLAHALDTGDDGGDPFIARLFETTLAPERGLDPQTAAKRVRRALRAFDQAAIHTIHAFCQRALQEAPFAAAMPFAFEMEADDGVLRFELAADFWRTRVEPVAAAYPAFAEWLVEYGAGPAALDAQLARRLKKPLARLRWDGLHAADDGAESAARAHFDTAAAIWRDERGVLGTLLADAQPSLNQRSHKPEAVSEALDAWARYFEQASAVAALPRAALKLTQSALEKATKKGGATPRHAFFDVAQALEAAVAALEAAQRARWLSLVEQWLDAAPAELAQRKRTRRVVSFDDLLANLYRALDAHPWLRETLRARYPAALIDEFQDTDPLQFAIFDTIFAPAGPLFLVGDPKQAIYSFRAADLHTYLAARARASARYTLAVNQRSTPAIVGACNRVFGANPRAFVLDGLDYEPVRAGSRVRAPLVDATDPLAGAGDFRIWTLPAGDDVLTKRDAQRHAAHACAAEIARLMRGARERAVTLGGEPLAASGIAVLVQTHRQGSLVKRVLAAWGIGSVELAQASVFATIDAEQLERVLAAIDAPGDLRRLRSALASDWFGLDAAALWRLEQGDAEQDGIDAAARGASGNGGGARAASAGAPAPSPADADAMGWVERFSRYRLLWRERGFAVMWRTLAGELRIAERLMAGADGERRVTDVNHLAELTQARASAQPGIAPTLRWLAAQRLEGGGDDAQLRLESDRNLVQIVTVHKSKGLEYAIVFCPFLNDGGLREPAGSGLPDAREYHDESGCAVLHYGCDDEAAERASREAVREQAAERARLVYVALTRAVYRCYLVAGTYQSSRSTKEARRSVLNWLVAGAGRDFDAWLKEPPEDAELAERWQALAGGPVTLGALPVPAHREPLAAGHDAQATRAARRATRGLRDAWRIASFSSLASAIARDESGIARAADDEMRPDHDALAAALGADALEPPDAAAAIAPAPAAAPRELAEDDILAFPRGAAAGECLHRLLELSNFADASTWPPAALRALHERPVEAELALAERLPAMMTRLVADLAATELVPGMRLAALDPARRLTEMEFLFPAPALDFNALRRLLAAHGYPDVALEAGTLAGFVKGFIDMIVEHDGRFWIVDWKSNHLGTTPEAYGERALDAAMAHHAYHLQALLYMVALHRYLRVRMRGYDYDAHIAGYLYVFVRGVRPDWRNGGASAGVHARRPARALIEALDALMREGDA
>NC_021884.1|WP_004521870.1|915988_919333_-|exodeoxyribonuclease-V-subunit-gamma
MLHLFYSNRHETLADALLDDLAFASDGAGPWAAQQVIVPSAALRRRLELDLAKRHGVCANVRFSYLAQWLWAQIGEVLTVPAHSPFAPDRLVWRCYRLLSDHGAAPWRASPRLAAYLAAADAPMRHELAHRIATVFDHYLTYRPEWLAQWQDGESIFALEGAPRHGGEAARDDEAWQAALWRALLAELSDSGMPPAHRFLREARAFDPDVIARARAKWPDAVSVFALPTMPPLHIALLRELSRWIDVRIYALNPCREFWFDIVTAARAESLDAADRLDYQEVGHPLLAEWGRQTQAQLHMLHELTESAAASDASRYADNPAPTWLARVQNAILDLQPEAALGEPPAERGVEVHVCHSLARQLEVLHDRLLAWFDADPSLAPSDVLVAMPDLATAGPLIDAVFGTPAGADAARIPYRITGLPPSQANPVARVLLDWLALPERDVGAPELVEWLRADAVAARYGIDATALETVQTWLAASGARRGLAPDAAEPPNPAVPAPRHTFADALTRLFLGYAMPDGAAPVSTWLPIAGAEGGEAELLGRLARFTDDLDGFARRIARDLTPQGWGDVFADALARFFDSGPAFADALSGVRDALDAMLAAMAEGAAGAALPAAVVRAGLAAALDDPARGGVPWGGVTFSSLTSLRGLPYRIVCLIGMDDGVLPSLARADEFDLMAVFAKLGDRQRRDDERNLFLDLLLAARERLLIAYTGRSIRDNAPLPPAALVDELLDHLAAASAGPDAPPDAVDAARRAFVIEHPLQPFSAEYFAPGGALFTYDASRATLARLLAEGARAQARPFFAAPLPAEPEQPVAFADFERFWRHPARSLLRARLGIVLLDAQAELVDTEPFELDYAGSDALAERVLPLLIETADAAAFEHALRVADASPEVPGGATGAVRRDHALDALAQLAGNVRRALADGATRVPFAFDVAPAWPAASDARWFGEHDAALAAAATREPLRLHGALARLTAAGQVIYRYARPGARDYLAAWLAHLVYCAIDPGGPRRTLWFGSGDTFEFAPVAAPLEQLAPLAALFRAGRRMPLAFFPRSAWALVSESESKAAGVWINDRVAGEADDASLALAWRGANPSLDEPFGALAHLVFDPLVEHLRRAS
>NC_021884.1|WP_004534567.1|919824_922101_+|FUSC-family-protein
MRYSVEIRKFFYSQYFFGGLRIALGVSLPAVLSLAVLHDRELGFTIATGALGACVVDMPGPLKYKHNEMLACSVIGFFSALATGLATPNIFALWLTIVPLTFALSLIVVYGNRWPQISFATLFMMVMTLEEKFTPLQALVNASWILAGGLWYTYWATIVSRWQARRIEQQALAESLFACASYLLARADFYDLDADLDECYRNLVARQITAVETQETARDIVLRNLPKLRRGKLDPGRTMMFNLFINSVDLHEMFVGAHTDYPLVRSTFGGSDLMIFYRDLIRKAAADLEEIGFAVLENRLPHSRISVKAELRAIEYEIELMRKKQFAATHPEAYAAVLATFRRIWSATRLIDKMRRNLSGSADAQRTELKIDKALTRFLQKRRMSPLLIFSNLNMGSPSLRHALRVTIAVAVGFWLGRLLPLTNAYWIVMTSIIILKPGYSLTKQRNAQRIVGTLIGCAASLALIYTVHEPHVLIAIMFGSMVMSYSLLLFNYAASVVFTSSYVLLLFHLLAPGNMRIIGERAIDTVVGCMIAIAASRLFPYWEYRAIGKLVADALATTRKYFEATWRAGRGKAAPAVPAADGAAAVPAVAAVVDAVAPGLDGDYQYRLARKNVHIAFANLGQAFQRMMLEPKAHQKFVPELNDLLVQTHVLGAQITAAAPLLRHACEQGNPPALERGMAAVREHLEQAEAGVPPPANQAETSKQLTRELDSMVVDAERSDAGADLAHDLKVLAHQCKQMLASSLLIRKDASVIRLPE
>NC_021884.1|WP_004192878.1|922097_922289_+|hypothetical-protein
MSRPPPPFLSTVSRRARTQGFPDYCPRASIGMIYPAPSCLYNFSSASAGPHRPADDTNHSETR
>NC_021884.1|WP_004192513.1|922285_923650_+|amino-acid-permease
MKNLQRHLSARHIRFLALGSAIGTGLFYGSASAIRLAGPAVILAYIVGGAAVYMVMRALGEMAVREPVPGSFGHYATENLGPFAGFVTGWTYTLEMVIVAIADITAFGIYMGFWFPHVPQWIWVLAIVAIICGLNLCHVKVFGELEFWLSIVKVGAIVAMIGGGAAILFTGMRLGSGGAPSLANLWSHGGFLPNGVGGLVASLSVVIFAYGGIEVIGMSAGEAKEPERVIPRAINAVPMRILLFYVLTMIVLMSIFPWTGVGANGSPFVQIFSALGVRSAAEILNLVVISAAISAINSDIFGAGRMMYAMALQGQAPRALAAMSARGVPWVTVLVMAGALLVGVVLNYLMPKDVFLMVAASATFATVWVWLMILLSQVAMRRRLGAAEVAALKFKVPFWPVGPALTIAFMAFVIAMLGYFDDTRVALFVGAAWLAILALVFYTRIRPRLAAVAR
>NC_021884.1|WP_004193167.1|923811_923991_-|hypothetical-protein
MNDPRSKKNPVFGVAILIVVVIALVIGTILYNAISQKHEYDEAHPHAASAASAASAQHG
>NC_021884.1|WP_004542994.1|924230_925286_+|Fe(3+)-ABC-transporter-substrate-binding-protein
MFVKQARPLLRMLLRPLAFAFALAAVAPAAHAANEVNLYTTREPKLIQPLVDAFTKQSGIAVNTVFVKDGLLERVKAEGARSPADVLMTVDIGNLLDLVDGGLTQPVRSASLDGAIPANLRGAGGNWYALSLRDRVLYVDKNMQLDAITYESLADPKWKGKVCVRSGQHPYNTALVAAMIAHDGEAAAEQWLRGVKANLARKATGGDRDVARDILGGICDIGLANAYYAGHMKHAQPGTDARKWGDAIKVVRPTFANAKSGGTHVNVSGAAVAKHAPNRDNAVKLLEYLASPPAQALYAQANYEYPVRAGVALDPVIAGFGPLKVDPLPLVEIAKYRKRASQLVDKVGFDN

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Crispr_ID: NC_021884_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021884_2

2191135-2191214

Orphan

Consensus_repeat	Method
ACGGAATGGGCCCCGGCATGATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021884_2

>merge|NC_021884|2|2191135-2191214|CRISPRCasFinder
ACGGAATGGGCCCCGGCATGATGGGCGGCGGCTACGGGCGCGGAATGACGGGCGGCTACGGAATGGGGCCCGGCATGATG

>NC_021884|2|2|2191135-2191214|CRISPRCasFinder
ACGGAATGGGCCCCGGCATGATG	GGCGGCGGCTACGGGCGCGGAATGACGGGCGGCT
ACGGAATGGGGCCCGGCATGATG

Protein	Signature genes	Signature genes Name	Protein_function
NC_021884.1\|WP_004543109.1\|2196217_2197159_-\|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl\|CDD\|223200
NC_021884.1\|WP_004524603.1\|2200818_2201379_-\|spermidine-N1-acetyltransferase	unknown	unknown	gnl\|CDD\|237916
NC_021884.1\|WP_004189258.1\|2186666_2187542_-\|N-carbamoylputrescine-amidase	unknown	unknown	gnl\|CDD\|274553
NC_021884.1\|WP_004543096.1\|2182199_2183204_+\|SIR2-family-protein	unknown	unknown	gnl\|CDD\|369676
NC_021884.1\|WP_004523118.1\|2194445_2196059_-\|glutamate--cysteine-ligase	unknown	unknown	gnl\|CDD\|235001
NC_021884.1\|WP_004524602.1\|2201540_2201711_+\|hypothetical-protein	unknown	unknown	unknown
NC_021884.1\|WP_020850573.1\|2197155_2198250_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	unknown	unknown	gnl\|CDD\|185333
NC_021884.1\|WP_004197761.1\|2198651_2199068_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319916
NC_021884.1\|WP_004200731.1\|2183740_2184223_+\|DUF2778-domain-containing-protein	unknown	unknown	gnl\|CDD\|378506
NC_021884.1\|WP_004543093.1\|2187552_2188665_-\|class-II-histone-deacetylase	unknown	unknown	gnl\|CDD\|212521
NC_021884.1\|WP_004525837.1\|2192167_2192716_+\|hypothetical-protein	unknown	unknown	unknown
NC_021884.1\|WP_004197759.1\|2199215_2199770_-\|YaeQ-family-protein	unknown	unknown	gnl\|CDD\|377782
NC_021884.1\|WP_161807729.1\|2186000_2186372_-\|hypothetical-protein	unknown	unknown	unknown
NC_021884.1\|WP_004543103.1\|2192978_2194427_+\|RNA-polymerase-sigma-factor-RpoD/SigA	unknown	unknown	gnl\|CDD\|274108
NC_021884.1\|WP_004200732.1\|2180921_2181326_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NC_021884.1\|WP_004201742.1\|2188693_2189788_-\|polyamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270377
NC_021884.1\|WP_004523107.1\|2184219_2184504_+\|hypothetical-protein	unknown	unknown	unknown
NC_021884.1\|WP_004543108.1\|2184576_2185668_-\|phage-portal-protein	unknown	unknown	gnl\|CDD\|222860
NC_021884.1\|WP_004543087.1\|2189930_2190899_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NC_021884.1\|WP_004536432.1\|2199985_2200333_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_021884.1\|WP_004543109.1\|2196217_2197159_-\|DNA-3-methyladenine-glycosylase-2-family-protein	gnl\|CDD\|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	5.53327e-54
NC_021884.1\|WP_004189258.1\|2186666_2187542_-\|N-carbamoylputrescine-amidase	gnl\|CDD\|274553	TIGR03381, putative_carbon-nitrogen_hydrolase, N-carbamoylputrescine amidase. Members of this family are N-carbamoylputrescine amidase (3.5.1.53). Bacterial genes are designated AguB. The AguAB pathway replaces SpeB for conversion of agmatine to putrescine in two steps rather than one. [Central intermediary metabolism, Polyamine biosynthesis].	0
NC_021884.1\|WP_004543096.1\|2182199_2183204_+\|SIR2-family-protein	gnl\|CDD\|369676	pfam08065, K167R, K167R (NUC007) repeat. This family represents the K167/Chmadrin repeat. The function of this repeat is unknown.	0.00506459
NC_021884.1\|WP_020850573.1\|2197155_2198250_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	gnl\|CDD\|185333	PRK15435, PRK15435, bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada.	2.13126e-121
NC_021884.1\|WP_004197761.1\|2198651_2199068_+\|VOC-family-protein	gnl\|CDD\|319916	cd07253, GLOD5, Human glyoxalase domain-containing protein 5 and similar proteins. Uncharacterized subfamily of VOC family contains human glyoxalase domain-containing protein 5 and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.46868e-30
NC_021884.1\|WP_004200731.1\|2183740_2184223_+\|DUF2778-domain-containing-protein	gnl\|CDD\|378506	pfam10908, DUF2778, Protein of unknown function (DUF2778). This is a bacterial family of uncharacterized proteins.	2.57059e-50
NC_021884.1\|WP_004543093.1\|2187552_2188665_-\|class-II-histone-deacetylase	gnl\|CDD\|212521	cd09996, HDAC_classII_1, Histone deacetylases and histone-like deacetylases, classII. This subfamily includes bacterial as well as eukaryotic Class II histone deacetylase (HDAC) and related proteins. Deacetylases of class II are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. Included in this family is a bacterial HDAC-like amidohydrolase (Bordetella/Alcaligenes species FB18817, denoted as FB188 HDAH) shown to be most similar in sequence and function to class II HDAC6 domain 3 or b (HDAC6b). FB188 HDAH is able to remove the acetyl moiety from acetylated histones, and can be inhibited by common HDAC inhibitors such as SAHA (suberoylanilide hydroxamic acid) as well as class II-specific but not class I specific inhibitors.	1.14721e-173
NC_021884.1\|WP_004197759.1\|2199215_2199770_-\|YaeQ-family-protein	gnl\|CDD\|377782	pfam07152, YaeQ, YaeQ protein. This family consists of several hypothetical bacterial proteins of around 180 residues in length which are often known as YaeQ. YaeQ is homologous to RfaH, a specialized transcription elongation protein. YaeQ is known to compensate for loss of RfaH function.	3.23549e-104
NC_021884.1\|WP_004523118.1\|2194445_2196059_-\|glutamate--cysteine-ligase	gnl\|CDD\|235001	PRK02107, PRK02107, glutamate--cysteine ligase; Provisional.	0
NC_021884.1\|WP_004543103.1\|2192978_2194427_+\|RNA-polymerase-sigma-factor-RpoD/SigA	gnl\|CDD\|274108	TIGR02393, RNA_polymerase_sigma_factor_RpoD, RNA polymerase sigma factor RpoD, C-terminal domain. This model represents the well-conserved C-terminal region of the major, essential sigma factor of most bacteria. Members of this clade show considerable variability in domain architecture and molecular weight, as well as in nomenclature: RpoD in E. coli and other Proteobacteria, SigA in Bacillus subtilis and many other Gram-positive bacteria, HrdB in Streptomyces, MysA in Mycobacterium smegmatis, etc. [Transcription, Transcription factors].	2.71742e-88
NC_021884.1\|WP_004200732.1\|2180921_2181326_-\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	4.3525e-28
NC_021884.1\|WP_004201742.1\|2188693_2189788_-\|polyamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	7.3532e-149
NC_021884.1\|WP_004543087.1\|2189930_2190899_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.91549e-71
NC_021884.1\|WP_004543108.1\|2184576_2185668_-\|phage-portal-protein	gnl\|CDD\|222860	PHA02536, Q, portal vertex protein; Provisional.	0
NC_021884.1\|WP_004524603.1\|2200818_2201379_-\|spermidine-N1-acetyltransferase	gnl\|CDD\|237916	PRK15130, PRK15130, spermidine N1-acetyltransferase; Provisional.	7.47948e-86

>NC_021884.1|WP_004543087.1|2189930_2190899_+|LysR-family-transcriptional-regulator
MRRIDLLSALETFVCAVEEGSLSQAARRLAKTPSAVTKAIAGLEATLGVQLLERTTRRLALTESGRLYLATATDVLRRLADGARQLSERDDEPRGLLRVTAAHSFGHAILAPLCAPFAQAFPRVRIELSLSDHYVDIVGEGFDLALRMGNYDLPSQIVKPIGSNRGLLCASPGYLARRGRPTAPADLAQHDCVIYRHPTLANTWTFERGGVRARLEPKGPLVTDDYGLALAAALDGAGVLPCPQWSVVDALEAGRLVPLLVDWRFESASFGEDRICAAYPSSRRGSTKIRRLVERVQARLADSEARVARVLGDALCADLARR
>NC_021884.1|WP_004201742.1|2188693_2189788_-|polyamine-ABC-transporter-substrate-binding-protein
MKRIAWLAAVLASLACAAARAADGNVLNIYNWAEYFAPDTIADFEKETGIKVRLDVYDSNEALQTKLTTGNSGYDLVFPSNDFLARQIQAGLYRKLDKSRLPNLTNLDPAIVARAAEVDPGNQYSVPYMQGTFGLGLNIAKVKQALGGPLPANTLELIFNPAYAAKLERCGIAFNDAGSEVFPLALRYIGRDPNTTDPRDYEAALDMMKKIRPTIRQFIATPVMNDLATGDVCVVTGYSGAVLVAARRAAEAKNGQQIVYSLPSAGAPFWFDSMAIPKGAAHADHALRFIDYILRPDVVAKISNKVMYPNPNRVATPLVDRRLTANPAIYPDAATMRTLWVKRPMPPQAMRMQTRYWTRFKTGY
>NC_021884.1|WP_004543093.1|2187552_2188665_-|class-II-histone-deacetylase
MIPTGLLFDPAFLSHRQGDLVYVVPHGTLNLGEHFDSPLRLAYTKQLLDAVGMTERLTRVAFARATDEQLLRVHRPEYLRQLAEACAVAGEQVVRLGDDAAGSASTEDVARLAAGAACAAVDAVMTGPLRQAYALIRPSGHHAGADFAMGYCYYNNVAIAARHAQAAHGVERVAIVDWDVHHGNGTQQAFYDDPSVLFVSLHEAANFPVDGGEARETGGGAGAGYNVNVPLPSGTGDAGYRHAFDELVLPLVEAFAPQLILVSAGQDANAFDPLGRMRVQRDGFRHMARALRQAAGGACGGRIVMLQEGGYSLPYLPIATLGVLEGLVGWNAPFDDPHQFVQYPLGEGERAAVKAARAALAPYWPTLHRS
>NC_021884.1|WP_004189258.1|2186666_2187542_-|N-carbamoylputrescine-amidase
MRKTTVAVTQMACDWNVDANLSRAERLVRDAAARGAQIVLLQELFETPYFCIDQHPAHLALAQPYEGHPWLMRFASLARELGVVLPVSFFERAGQTQFNSVAIFDADGRALGIYRKTHIPDGPGYTEKYYFTPGDTGFRVWDTAYGRIGVGICWDQWFPECARAMALAGAELLLYPSAIGSEPHDASIDSRAHWRNAQRGHAAANLMPVAASNRVGVERGASGEIVFYGSSFIAGADGEMIVECDRHGEAIATAEFDLDALAYRRRGWGVFRDRRPECYRALSEGAADRVR
>NC_021884.1|WP_161807729.1|2186000_2186372_-|hypothetical-protein
MPPSVRPPRGRHVRAIGAGRRGNASGRFATTFCWGAQARGRAVADRGVAFDCEDAEAAAQLLEHAIALEEVDLMREDAILGDGKPDVVRAAEITFLYRAELHRGGSPRAVGLGMLYFRGSSDH
>NC_021884.1|WP_004543108.1|2184576_2185668_-|phage-portal-protein
MSSWRRRASTTAPSACSNVTSSAATTLRNRPRQIRAPARAEVFTFDDPTPVMNRAEILDYVECWSNGEWFEPPVSFAGLAKSFRASTHHSSALFFKANVLASTFRPHRWLSRHAFERWALDFLTFGNGYLERRRNMVGGTLRLEPALAKYVRRKADFSGFVYVNGWQDRHEFAPDSVFQLVRPDINQEVYGLPEYLSSLHSAWLNESSTLFRRKYYENGSHAGFILYMIDAAQKQDDVDNMRDALKNAKGPGNFRNVFMYAPGGKKDGIQLIPVSEVAAKDEFFNIKNVTRDDLLAAHRVPPQLLGIVPSNSGGFGTPDTAARVFGRNEIRPLQARFAELNDWLGEEVVTFDDYEIPPAPVAA
>NC_021884.1|WP_004523107.1|2184219_2184504_+|hypothetical-protein
MKTIGRILLALVLTWPLLTGISSLPLLTHWFANGGEGWNALSPVFRALGSDGGEQNEEIFVGILLVISFVLALVLSFALFGLVDRLRHSTDRRA
>NC_021884.1|WP_004200731.1|2183740_2184223_+|DUF2778-domain-containing-protein
MPAECTFVLNRSRLSTLTCPGFGSVPAFSGNGRYINDPGSTAVADKGPLPAGVYYIIDRQSGGHLGWFRDTVMDAALNTYRAEWFALYRIDGQIDDWTIVNGIRRGHFRLHPVGRLGESDGCITLTSRGQFDKLRAFLKAQPTTQVPGTSFRAYGKVTVK
>NC_021884.1|WP_004543096.1|2182199_2183204_+|SIR2-family-protein
MAQKKKVVYFLGAGASFGAGAKATVQAGHQLPIPTQATFWPTFLRFCKSQKNCARIESFLFRYFLGYGKTPVRTPAAKRRHLLTSIDVEEVFTFLSERTRAPSTSTQLRTYALQVWGALAEEIGQVFSRFNANSATKAIYKDFLKHHFRRFDTVVSFNYDTIFENSLPARRSARYVGLRDSAGTIPLLKPHGSVNWVQADDGTITVGNPVGPAVIVAPTHLKFISDPDQKEVQHPGYLDQAHEIQKIWAEMEREMRFARSLVFIGYSFPVADLYFASVLRSVLADRDTTPNIVIVNPDAVAISERLLRRFPLVTVSRFFDLAQFIRAGRAVIAQ
>NC_021884.1|WP_004200732.1|2180921_2181326_-|PaaI-family-thioesterase
MDENTVRDLLDRLLAPWVRSLSLTPVSISEESVTLRLPFSGEFRHSGGVICGQVFMAAADTAMVVAISAALGEFRPMTTVALNTHFMRPVRKGDVLVTARVLRMGRNLVFGEIELFDEDGKMAVHATSTYALVS
>NC_021884.1|WP_004525837.1|2192167_2192716_+|hypothetical-protein
MEEAYARRALLLHLGSVLQILSRLEGAPDNQSIEALLAANGMLADVPLVEYVVQDMTVREFSARALRAFCLWPQLLLEDPLDCAALALPVRKHLFAGNDAGWKAYAATLREVSPGFDTARSYAAEPHEAEFDLADERDAETGDGPVERDDEADDDGRLRERAAASVESATPAGAPVRRESYE
>NC_021884.1|WP_004543103.1|2192978_2194427_+|RNA-polymerase-sigma-factor-RpoD/SigA
MKVSARELRYEQGIDRLLELAGARDDTEYADVADEFASAPSSAFAHDLGEPDSLDHQASDESAGAGSFGDKPTRPAHGDTDVDTDWRDDDAPPSGSNDAAPVDTAASTDPLALFVRRMHAVPLLTHAQEIALAAEIEAGREQVLQALAEALDRLDLASLPADPALGRARAALQRARARGDEGARAFARARTAAYAALAAHGWPSAEVDAVRRAMRRLPTSPEKSDAGAQRAFADGEARISAATARMAEANLRLVLSIARKYASRGLDLADLLQEGNLGLLRAIEKFEHRRGFKFSTYATWWIRQAISRAIADRARTIRVPVHVGDEARRVRKAADRIERRSGVSASLAELSEATGLPAERLRAVLTLPREPRSLNAPLGDDDQAEFGDIVEDTSTPSLFDALAHGQMCDVVTSLLKTMSAQEADILRRRFGIGGDEPWSYEQIAARAGVSREQVRRIEKRALQTLRVTAEACNAHDFLDVQP
>NC_021884.1|WP_004523118.1|2194445_2196059_-|glutamate--cysteine-ligase
MPNNMTSRQTDLLQQRLAVLSTSPTREQLPDGLRGIEKESLRVTRDGMIAFTPHPRALGSALTHPSLTTDYSEALVELITPAERDAATTLERLDELHRYVYASLGDEMLWTDSMPGLLPADDEIPIADYGTSNIGRLKTVYRRGLAYRYGRTMQCIAGIHYNYSLSEEVWRRLHAEEGSTASIVDYQSERYLALIRNFRRTSWLLMYLFGASPALDAGFLRGRAHKLDTFDAATLYRPHATSLRMSDLGYSNTTAQAALQADYNTLSGYLDALSKAVSEPYPPYEAIGTHRDGEWIQINTNVLQIENEFYSTIRPKRVTYSGERPLHALASRGVQYIEVRCLDIDPFEPTGIALDTARFLDAYLLVCALDESAPLTCDAYRESNANFGRVTMEGRKPGLELTRDGAAVPMRAWADEIFAQIEAAGRVLDDIRGDDAHARAIAAQRAKLDDPELTSSARVLRAMRENGQSFLEFARAQSAAHAAYFHGRPLDEAATRDARALAERSLAEQAELEGKNAGSFDAFVAAYRAYTLNRFSV
>NC_021884.1|WP_004543109.1|2196217_2197159_-|DNA-3-methyladenine-glycosylase-2-family-protein
MSAAVEPAAVRPDSVVLELPFKSPYDWPRVLRFFAGRAIPGVEAVGDGAYRRTVDHHGAIGTLTVRKHPRKRCLVALVEGDAARHADAAFAARLSTMFDLQADLAAIGAHLARDAWFAPLVGAAPGLRVPGAWSGFELIVRAIVGQQVSVKAATTIVGRLVERAGERLAPHAPGAIGWRFPEPAALAACDLSRIGMPGKRAAALQGVARAVAAGDVPLDAYASDPAGVRAALLALPGIGPWTVEYVAMRAWRDADAWPATDLVLMQAIVARDPALDRPASQRLRADAWRPWRAYAAMHLWNEIADRAGSARGG
>NC_021884.1|WP_020850573.1|2197155_2198250_-|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada
MKQPPYPTDDARWAALVARDVDADGAFCYAVKTTGVFCRPSCASRLPRRENVSFFVDTGAARAAGYRPCKRCRPEGLPRELDIVNRACAVLDAHRQDRFTLAQLSDAVHVSPFHLQRLFKRVVGVSPRQYQAAQRGAALRDALQSGAAVTRAAVDAGFNSPSRLYESVPRELGMSPSAFRRKGAGLKIDYATADTRLGVVLVAATSKGICKIAFGDAAAPLVDELRTGFANAQIAESPERIAPFIAQVDAYLNGTRRRFELPLDLAATEFQQRVWDALRRIPYGETRSYTQIAEALGAPRAVRAVASACASNPVALAIPCHRVVQKGGSLAGYRWGLPRKAALLDAEAQRAAGESVESAVDHAA
>NC_021884.1|WP_004197761.1|2198651_2199068_+|VOC-family-protein
MKFHIHEIDHVVLRAADLAAMTRFYCDVLGCHVEKEQRELGLVQLRAGRSLIDLLAVGAPIDRAGSGAPGKGRNMDHLCLRVEPFDAAALRTHLAAHGARPGDEARRYGADGYGPSLYLFDPEGNMVELKGPPEAVAP
>NC_021884.1|WP_004197759.1|2199215_2199770_-|YaeQ-family-protein
MALKSTIYKAELQIADMDRHYYADHSLTVARHPSETDERMMVRIAAFALFAHERLEFCKGLSDTDEPDLWQKDLTGAIEVWIDVGQPDERRIAKASGRAGRVNVIAYGGRTSDIWWQGARGKVERLRNVQVTTLADGVAAALGGLAERTMRLQCTIQDGAAWLSSATHDPVAIEWTTLKAREDA
>NC_021884.1|WP_004536432.1|2199985_2200333_-|hypothetical-protein
MLKRTGLFLALAGGIVAFSVAQANGDASLKPQQEIQLTKNAWGCLSKDNLDSVLNHERDGKAQAKQQYFDDYRCLSVPEGQRFRVVSVDKGDVQFVSAENSDQQGLWTDARFIKQ
>NC_021884.1|WP_004524603.1|2200818_2201379_-|spermidine-N1-acetyltransferase
MQIQNEQHTLALRPLERQDLRFVHELNNDAKIMRYWFEEPYETFTELSQLYDQHVHDQRERRFVAFDSDGELVGLVELIELDYIHRRGEFQIIIAPNRQGRGFATRATRLAVEYAFKVLNLRKLYLIVDKSNVAAIRVYEKCGFKHEAELIEEFFGNGQYHNALRMCIFQRDYFAAQPGAELHARE
>NC_021884.1|WP_004524602.1|2201540_2201711_+|hypothetical-protein
MIEQVILGVFLVLPLLIVAVLYSDELWQEHRLQHPRDEHTPHIDWRHPWRILRRGH

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1354755 : 1365712

Agrobacterium_phage(16.67%)

protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004196461.1\|1354755_1357056_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.1e-167	42.1
WP_004194131.1\|1357052_1357367_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6
WP_004196460.1\|1357899_1358103_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004541727.1\|1358232_1359843_-	multicopper oxidase family protein	NA	NA	NA	NA
WP_004189626.1\|1359855_1360038_+	hypothetical protein	NA	NA	NA	NA
WP_004189552.1\|1360010_1361270_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_004189780.1\|1361537_1362116_+	pseudouridine synthase	NA	NA	NA	NA
WP_071810810.1\|1362377_1362596_+	hypothetical protein	NA	NA	NA	NA
WP_004530837.1\|1362787_1363297_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.5e-13	41.2
WP_004197486.1\|1363597_1365712_+	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7

DBSCAN-SWA_2

2120502 : 2185668

Streptococcus_phage(12.5%)

transposase,portal,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020850758.1\|2120502_2121966_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	1.2e-79	38.3
WP_004199069.1\|2122070_2123258_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	2.2e-121	60.7
WP_004523078.1\|2123523_2124408_+	lipid A biosynthesis lauroyl acyltransferase	A0A1W6JP29	Morganella_phage	7.3e-29	30.1
WP_004199067.1\|2124448_2125318_+	diaminopimelate epimerase	NA	NA	NA	NA
WP_020850774.1\|2125365_2126079_+	DUF484 family protein	NA	NA	NA	NA
WP_004523080.1\|2126116_2127049_+	tyrosine recombinase XerC	G1JX48	Mycobacterium_phage	2.4e-14	28.0
WP_004542863.1\|2127137_2128415_+	class I SAM-dependent rRNA methyltransferase	NA	NA	NA	NA
WP_009972676.1\|2128592_2129678_+	GTP-binding protein	NA	NA	NA	NA
WP_004198318.1\|2130227_2130644_+	RNA polymerase-binding protein DksA	NA	NA	NA	NA
WP_004203414.1\|2130898_2131435_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_004198316.1\|2131444_2132788_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	3.7e-40	28.8
WP_004198315.1\|2133214_2133757_-	response regulator transcription factor	NA	NA	NA	NA
WP_004198314.1\|2133776_2135057_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_004198312.1\|2135074_2135326_-	cysteine-rich CWC family protein	NA	NA	NA	NA
WP_004200214.1\|2135650_2136550_+	acetylglutamate kinase	NA	NA	NA	NA
WP_004198307.1\|2136546_2137350_+	pyrimidine 5'-nucleotidase	NA	NA	NA	NA
WP_004525865.1\|2137316_2138009_+	nucleoid occlusion factor SlmA	NA	NA	NA	NA
WP_004198305.1\|2138358_2139504_+	homoserine O-acetyltransferase	NA	NA	NA	NA
WP_004543091.1\|2139500_2140115_+	methionine biosynthesis protein MetW	NA	NA	NA	NA
WP_004523086.1\|2140126_2141440_+	AmpG family muropeptide MFS transporter	NA	NA	NA	NA
WP_004535313.1\|2141429_2142482_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_004525862.1\|2142854_2143799_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004523088.1\|2144010_2145075_+	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L339	Tupanvirus	1.3e-80	45.8
WP_004191998.1\|2145349_2146813_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004190029.1\|2146973_2147744_-	exodeoxyribonuclease III	R4TWA8	Phaeocystis_globosa_virus	3.4e-30	33.8
WP_004523089.1\|2147776_2148616_-	polyphosphate kinase	NA	NA	NA	NA
WP_004523090.1\|2148742_2150215_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_004525859.1\|2150217_2151708_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_004189769.1\|2151820_2152120_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_004189550.1\|2152485_2153529_+	rod shape-determining protein	NA	NA	NA	NA
WP_004189331.1\|2153648_2154722_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_004523092.1\|2154718_2155231_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_004543095.1\|2155414_2157826_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_004189171.1\|2157837_2158986_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_004543106.1\|2159279_2160056_-	sel1 repeat family protein	NA	NA	NA	NA
WP_004189570.1\|2160052_2160838_-	2-dehydro-3-deoxyglucarate aldolase	NA	NA	NA	NA
WP_004189793.1\|2161262_2161715_-	6-carboxytetrahydropterin synthase QueD	A0A088FAL2	Vibrio_phage	7.6e-14	30.8
WP_004189241.1\|2161734_2162367_-	7-carboxy-7-deazaguanine synthase	R4TAH8	Halovirus	2.1e-06	30.9
WP_004190026.1\|2162460_2163195_-	7-cyano-7-deazaguanine synthase QueC	A0A1B0Z0B4	Vibrio_phage	1.6e-50	42.5
WP_004189647.1\|2163662_2164346_-	response regulator	NA	NA	NA	NA
WP_004523096.1\|2164346_2166755_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_004543101.1\|2166756_2167347_-	DUF4390 domain-containing protein	NA	NA	NA	NA
WP_020850535.1\|2167343_2168753_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_004189409.1\|2169248_2170106_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_004543107.1\|2170215_2170851_-	LysE family translocator	NA	NA	NA	NA
WP_004543102.1\|2170971_2171955_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.3e-07	38.0
WP_004525852.1\|2171986_2172490_-	peptide deformylase	A0A067XQZ3	Caulobacter_phage	2.1e-12	34.3
WP_020850823.1\|2172718_2173909_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	2.0e-21	39.2
WP_004190199.1\|2173968_2174340_+	thioredoxin family protein	NA	NA	NA	NA
WP_004523103.1\|2174550_2177160_+	DNA topoisomerase III	A0A2P1ELA0	Moumouvirus	7.7e-18	25.7
WP_004189230.1\|2177383_2178439_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004523104.1\|2178877_2179894_+	D-2-hydroxyacid dehydrogenase family protein	NA	NA	NA	NA
WP_004543112.1\|2180014_2180884_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_004200732.1\|2180921_2181326_-	PaaI family thioesterase	NA	NA	NA	NA
WP_004543096.1\|2182199_2183204_+	SIR2 family protein	NA	NA	NA	NA
WP_004200731.1\|2183740_2184223_+	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_004523107.1\|2184219_2184504_+	hypothetical protein	NA	NA	NA	NA
WP_004543108.1\|2184576_2185668_-\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	2.2e-192	91.7

DBSCAN-SWA_3

2400031 : 2411250

Burkholderia_virus(22.22%)

integrase

attL 2397444:2397461|attR 2414030:2414047

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2397444:2397461	attL	NA	NA	NA	NA
WP_004524472.1\|2400031_2402119_+	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	1.9e-99	35.8
WP_004202928.1\|2402441_2403341_-	c-type cytochrome	NA	NA	NA	NA
WP_041188602.1\|2404523_2405111_+\|integrase	site-specific integrase	A0A0S2SYQ7	Pseudomonas_phage	3.1e-44	50.6
WP_009922658.1\|2405490_2405808_+	helix-turn-helix transcriptional regulator	A0A088CD40	Shigella_phage	6.2e-15	57.0
WP_004541800.1\|2405807_2406725_+	DUF4935 domain-containing protein	A4PE40	Ralstonia_virus	8.9e-46	40.6
WP_009922654.1\|2406978_2407521_+	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	3.3e-48	56.4
WP_009932249.1\|2407778_2408231_+	VRR-NUC domain-containing protein	Q8W6S1	Burkholderia_virus	2.3e-31	58.8
WP_004525722.1\|2408230_2409310_+	DUF3396 domain-containing protein	A9YX32	Burkholderia_phage	2.2e-160	99.0
WP_004525721.1\|2409466_2409715_+	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	4.0e-41	97.6
WP_004195754.1\|2410605_2411250_+	lytic polysaccharide monooxygenase	A0A0K1Y848	Apis_mellifera_filamentous_virus	5.7e-07	30.4
2414030:2414047	attR	NA	NA	NA	NA

DBSCAN-SWA_4

2655509 : 2682071

Burkholderia_phage(44.44%)

tail,protease,plate,integrase

attL 2656082:2656128|attR 2671559:2671605

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004527881.1\|2655509_2656031_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.9e-21	51.0
2656082:2656128	attL	NA	NA	NA	NA
WP_004542707.1\|2656224_2657271_+\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	3.9e-53	38.7
WP_004542657.1\|2659033_2659288_+	hypothetical protein	NA	NA	NA	NA
WP_004542680.1\|2659301_2659952_+	hypothetical protein	NA	NA	NA	NA
WP_020850759.1\|2659963_2660356_+	hypothetical protein	NA	NA	NA	NA
WP_004542725.1\|2660348_2661197_+	type IV secretion system protein	NA	NA	NA	NA
WP_143291333.1\|2661256_2661508_+	hypothetical protein	NA	NA	NA	NA
WP_004542660.1\|2661660_2661942_+	hypothetical protein	NA	NA	NA	NA
WP_004542720.1\|2662360_2665336_+	conjugative relaxase	V5UQN3	Mycobacterium_phage	4.5e-06	28.8
WP_020850657.1\|2665361_2665613_-	hypothetical protein	NA	NA	NA	NA
WP_076847806.1\|2666087_2666534_+	hypothetical protein	NA	NA	NA	NA
WP_004542662.1\|2666530_2666800_+	hypothetical protein	NA	NA	NA	NA
WP_020850845.1\|2666816_2667476_+	hypothetical protein	NA	NA	NA	NA
WP_004542700.1\|2667588_2668503_-	three-Cys-motif partner protein TcmP	NA	NA	NA	NA
WP_076847687.1\|2668514_2669357_-	phage Gp37/Gp68 family protein	Q8W6R4	Burkholderia_virus	2.9e-67	43.3
WP_076847807.1\|2669651_2670290_+	DUF4433 domain-containing protein	NA	NA	NA	NA
WP_020850538.1\|2670304_2671366_+	macro domain-containing protein	B3FJ30	Pseudomonas_phage	3.1e-18	36.5
WP_004542696.1\|2672208_2672535_+\|plate	baseplate J-like protein, truncation	K4NZR5	Burkholderia_phage	1.3e-52	100.0
2671559:2671605	attR	NA	NA	NA	NA
WP_004542714.1\|2672527_2672941_+\|tail	phage tail protein I	K4NXA0	Burkholderia_phage	1.5e-69	99.2
WP_020850622.1\|2672958_2673441_+	DNA methylase	K4NZW3	Burkholderia_phage	4.5e-73	87.6
WP_111952238.1\|2673834_2674425_+	hypothetical protein	NA	NA	NA	NA
WP_004542688.1\|2674528_2674894_-	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	5.1e-53	89.3
WP_004521948.1\|2674995_2675781_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004521949.1\|2675777_2677124_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004521950.1\|2677232_2677847_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004531875.1\|2678221_2678893_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004521952.1\|2678929_2679448_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004521953.1\|2679464_2680955_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004527837.1\|2681027_2681531_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004204912.1\|2681588_2682071_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_5

3031530 : 3040775

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004194034.1\|3031530_3033483_+	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2
WP_004533593.1\|3033749_3034880_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	3.8e-22	27.6
WP_004541188.1\|3034913_3036920_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	4.8e-52	34.6
WP_004194137.1\|3037103_3037919_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004532195.1\|3037983_3038667_-	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.0e-05	26.0
WP_004194373.1\|3038663_3039191_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004541275.1\|3039227_3040775_-	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	1.2e-23	30.9

DBSCAN-SWA_6

3378977 : 3387792

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004522358.1\|3378977_3380378_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.9e-79	38.5
WP_009921652.1\|3380409_3381333_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.3e-15	27.1
WP_004190173.1\|3381391_3382384_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_004539941.1\|3382455_3382773_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_004532363.1\|3383096_3383999_+	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	1.9e-53	39.9
WP_004539874.1\|3384225_3385509_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004522362.1\|3385687_3386611_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	2.4e-43	36.2
WP_041188594.1\|3386949_3387792_-	alpha/beta hydrolase	A7XCB7	Tanapox_virus	7.2e-18	27.0

DBSCAN-SWA_7

3462894 : 3542132

Burkholderia_virus(30.3%)

portal,head,terminase,integrase,holin,tail,protease

attL 3469440:3469457|attR 3492230:3492247

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004192020.1\|3462894_3464403_+\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	2.8e-20	27.7
WP_004539792.1\|3464399_3464654_+	glutaredoxin family protein	NA	NA	NA	NA
WP_004193305.1\|3464895_3466689_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	2.1e-22	23.5
WP_004193513.1\|3466704_3467598_+	signal peptidase I	NA	NA	NA	NA
WP_004539775.1\|3467748_3469152_+	ribonuclease III	G8DDA3	Micromonas_pusilla_virus	4.9e-19	30.3
WP_004191678.1\|3469221_3470121_+	GTPase Era	NA	NA	NA	NA
3469440:3469457	attL	NA	NA	NA	NA
WP_004524618.1\|3470140_3470968_+	DNA repair protein RecO	NA	NA	NA	NA
WP_004192885.1\|3470964_3471738_+	pyridoxine 5'-phosphate synthase	NA	NA	NA	NA
WP_004191194.1\|3471743_3472175_+	holo-ACP synthase	NA	NA	NA	NA
WP_004539664.1\|3472202_3473231_+	beta-N-acetylhexosaminidase	NA	NA	NA	NA
WP_004192300.1\|3473344_3474742_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_004193484.1\|3475013_3475571_-	elongation factor P	NA	NA	NA	NA
WP_004540031.1\|3475760_3476981_-	elongation factor P maturation arginine rhamnosyltransferase EarP	NA	NA	NA	NA
WP_004527460.1\|3477204_3479448_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_004192722.1\|3479575_3480169_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_004539938.1\|3480933_3482133_+\|integrase	tyrosine-type recombinase/integrase	A0A1L7DQ84	Ralstonia_phage	7.9e-18	34.7
WP_080002859.1\|3482149_3483097_-	conjugal transfer protein TraN	NA	NA	NA	NA
WP_004539756.1\|3483140_3483467_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_020850651.1\|3483463_3483724_-	hypothetical protein	NA	NA	NA	NA
WP_041188621.1\|3483720_3484065_-	hypothetical protein	X5I2N5	Pseudomonas_phage	6.7e-31	71.0
WP_076847822.1\|3485344_3485683_-	hypothetical protein	NA	NA	NA	NA
WP_004539721.1\|3485784_3487101_-	hypothetical protein	NA	NA	NA	NA
WP_004539952.1\|3487100_3487547_-	hypothetical protein	NA	NA	NA	NA
WP_004539947.1\|3487543_3487903_-	hypothetical protein	NA	NA	NA	NA
WP_020850499.1\|3487907_3488117_-	hypothetical protein	NA	NA	NA	NA
WP_004539642.1\|3488124_3488277_-	hypothetical protein	NA	NA	NA	NA
WP_020850728.1\|3488279_3488495_-	hypothetical protein	NA	NA	NA	NA
WP_020850435.1\|3489061_3489589_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004539980.1\|3489682_3489889_+	hypothetical protein	NA	NA	NA	NA
WP_020850469.1\|3489963_3490488_+	hypothetical protein	C7BGG0	Burkholderia_phage	6.2e-28	45.0
WP_004540057.1\|3490496_3490889_+	hypothetical protein	NA	NA	NA	NA
WP_004539611.1\|3491043_3493782_+	virulence protein E	A0A2D1GN57	Marinobacter_phage	1.1e-91	43.3
3492230:3492247	attR	NA	NA	NA	NA
WP_076847724.1\|3494061_3494859_+	hypothetical protein	NA	NA	NA	NA
WP_004539817.1\|3495077_3495836_+	hypothetical protein	A0A1B0Z000	Pseudomonas_phage	5.0e-34	42.7
WP_020850831.1\|3496017_3496647_+	hypothetical protein	A0A2H4JCL4	uncultured_Caudovirales_phage	1.6e-06	32.3
WP_020850857.1\|3496594_3498664_+\|terminase	phage terminase large subunit family protein	A0A1B2LRQ2	Wolbachia_phage	1.3e-100	34.0
WP_004540003.1\|3498666_3498873_+	hypothetical protein	A0A2H4JA19	uncultured_Caudovirales_phage	6.5e-05	46.8
WP_004539741.1\|3498874_3500398_+\|portal	phage portal protein	B7SYD6	Stenotrophomonas_phage	1.2e-84	38.6
WP_020850433.1\|3500387_3502466_+\|head,protease	caudovirus prohead protease family protein	A0A076G7Y9	Pseudoalteromonas_phage	1.9e-67	29.8
WP_004540064.1\|3502531_3502867_+	DUF2190 family protein	NA	NA	NA	NA
WP_004539750.1\|3502869_3503166_+	hypothetical protein	NA	NA	NA	NA
WP_004539916.1\|3503162_3503588_+	hypothetical protein	NA	NA	NA	NA
WP_020850716.1\|3503618_3504557_+	hypothetical protein	G8CLB2	Synechococcus_phage	9.7e-48	36.8
WP_004540052.1\|3504615_3504954_+	hypothetical protein	F4YCS5	Synechococcus_phage	1.8e-07	29.1
WP_043944506.1\|3505025_3505331_+	DUF1799 domain-containing protein	A0A0H5ARS5	Pseudomonas_phage	7.6e-10	44.3
WP_004539854.1\|3505375_3508156_+\|tail	phage tail length tape measure family protein	C4ML16	Xanthomonas_virus	1.3e-18	26.1
WP_076847725.1\|3508145_3508484_+\|tail	phage tail protein	K7PHL4	Enterobacterial_phage	2.4e-17	42.3
WP_020850804.1\|3508485_3509889_+\|tail	tail fiber domain-containing protein	Q8W6T4	Burkholderia_virus	3.0e-194	75.9
WP_004539780.1\|3509885_3510578_+\|tail	phage minor tail protein L	Q6JIL5	Burkholderia_virus	2.9e-81	65.0
WP_004539701.1\|3510582_3511314_+	C40 family peptidase	Q8W6T2	Burkholderia_virus	1.3e-63	50.4
WP_004539859.1\|3511310_3511892_+\|tail	tail assembly protein	Q3HQU4	Burkholderia_phage	6.9e-52	55.7
WP_004540110.1\|3511888_3515260_+	host specificity protein J	A4JX16	Burkholderia_virus	2.8e-302	48.3
WP_020850420.1\|3515259_3515565_+	hypothetical protein	Q8W6S9	Burkholderia_virus	1.6e-39	73.5
WP_020850642.1\|3515564_3516302_+	hypothetical protein	Q8W6S8	Burkholderia_virus	2.8e-98	68.0
WP_004539903.1\|3516359_3516644_+\|holin	holin	C7BGD7	Burkholderia_phage	4.7e-38	90.4
WP_020850783.1\|3516646_3517141_+	glycoside hydrolase family 104 protein	Q6J1Q5	Burkholderia_virus	6.9e-69	79.9
WP_004540004.1\|3517137_3517632_+	DUF2514 family protein	Q6J1Q4	Burkholderia_virus	6.7e-32	54.5
WP_004539787.1\|3517799_3518588_+	DNA adenine methylase	Q8W6S4	Burkholderia_virus	6.1e-144	90.5
WP_004540087.1\|3518698_3519586_+	hypothetical protein	Q8W6S3	Burkholderia_virus	2.1e-92	64.1
WP_004539830.1\|3519692_3520082_-	hypothetical protein	NA	NA	NA	NA
WP_041188619.1\|3520119_3520380_-	hypothetical protein	C7BGE3	Burkholderia_phage	2.8e-37	83.7
WP_144084165.1\|3520344_3520848_+	SOS response-associated peptidase family protein	A0A1S5NTJ1	Burkholderia_phage	8.3e-70	85.8
WP_004539946.1\|3520888_3521830_-	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_158332260.1\|3521974_3522037_+	hypothetical protein	NA	NA	NA	NA
WP_004193834.1\|3523292_3523805_-	GAF domain-containing protein	NA	NA	NA	NA
WP_004197652.1\|3523969_3524878_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004191946.1\|3525004_3525871_+	pirin family protein	NA	NA	NA	NA
WP_004554230.1\|3526112_3526616_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004191283.1\|3526750_3527623_-	cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_004192175.1\|3527633_3528080_-	copper chaperone PCu(A)C	NA	NA	NA	NA
WP_004539914.1\|3528106_3528805_-	SCO family protein	NA	NA	NA	NA
WP_076847727.1\|3528971_3529193_-	hypothetical protein	NA	NA	NA	NA
WP_004533988.1\|3529125_3529935_+	trehalose-phosphatase	NA	NA	NA	NA
WP_004203013.1\|3529931_3531308_+	alpha,alpha-trehalose-phosphate synthase (UDP-forming)	NA	NA	NA	NA
WP_004539709.1\|3531369_3533241_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.7e-38	27.1
WP_004192961.1\|3533807_3534872_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_004535747.1\|3535138_3536110_+	hypothetical protein	NA	NA	NA	NA
WP_004204640.1\|3536165_3536627_+	DUF2214 family protein	NA	NA	NA	NA
WP_004524631.1\|3536776_3537949_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_004191212.1\|3538047_3539196_-	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004191603.1\|3540029_3542132_-\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA

DBSCAN-SWA_8

3692675 : 3785056

100

uncultured_Caudovirales_phage(22.73%)

capsid,portal,head,lysis,terminase,plate,integrase,tail,tRNA,protease

attL 3701447:3701465|attR 3759628:3759646

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004192783.1\|3692675_3694202_-\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	2.8e-84	35.6
WP_004199566.1\|3694295_3695400_-	peptide chain release factor 2	A0A0S4KWG0	Pseudomonas_phage	2.2e-06	37.1
WP_004191649.1\|3695739_3697434_-	single-stranded-DNA-specific exonuclease RecJ	A0A0K2FM92	Brevibacillus_phage	1.1e-28	27.3
WP_004193226.1\|3697449_3698526_-	hypothetical protein	NA	NA	NA	NA
WP_004540060.1\|3699093_3700347_+	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_004195923.1\|3700339_3701089_+	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	2.2e-34	38.3
WP_004192516.1\|3701093_3701882_+	TatD family hydrolase	NA	NA	NA	NA
3701447:3701465	attL	NA	NA	NA	NA
WP_020850592.1\|3701934_3704463_+	DNA internalization-related competence protein ComEC/Rec2	NA	NA	NA	NA
WP_004540067.1\|3704499_3705327_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004192790.1\|3705583_3707245_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.9e-150	52.0
WP_004539923.1\|3707241_3708096_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	8.9e-48	40.9
WP_004192585.1\|3708199_3709483_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	6.4e-151	62.6
WP_004191789.1\|3709574_3710006_+	cell division protein FtsB	NA	NA	NA	NA
WP_004532146.1\|3710231_3710579_-	hypothetical protein	NA	NA	NA	NA
WP_004191092.1\|3710662_3711613_-	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_004524734.1\|3711651_3712176_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_004191514.1\|3712385_3713204_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_004192762.1\|3713358_3714249_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_004193008.1\|3714516_3715347_+	PHP domain-containing protein	NA	NA	NA	NA
WP_004192132.1\|3715411_3716041_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_004192745.1\|3716139_3716805_+\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_004191887.1\|3716813_3718016_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_004192474.1\|3718012_3718630_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004191516.1\|3718674_3719577_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_004524737.1\|3719687_3720830_+	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_004193059.1\|3720834_3721611_+	MBL fold metallo-hydrolase	U5PVD0	Bacillus_phage	3.3e-09	26.6
WP_004539920.1\|3722337_3723525_-	cupin domain-containing protein	NA	NA	NA	NA
WP_004524740.1\|3723593_3724139_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_004540138.1\|3724118_3725417_-	hypothetical protein	NA	NA	NA	NA
WP_004539925.1\|3725403_3728088_-	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	9.3e-27	24.3
WP_004539636.1\|3728247_3729549_+\|integrase	integrase family protein	C7BGE7	Burkholderia_phage	1.8e-148	58.9
WP_009890227.1\|3729499_3729742_-	AlpA family phage regulatory protein	C7BGF0	Burkholderia_phage	9.3e-19	59.2
WP_004539932.1\|3729750_3730224_-	hypothetical protein	B5TA88	Burkholderia_phage	2.3e-05	71.4
WP_004555250.1\|3730232_3730562_-	hypothetical protein	NA	NA	NA	NA
WP_004540046.1\|3730675_3731992_-	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_004539832.1\|3731991_3732441_-	hypothetical protein	NA	NA	NA	NA
WP_004534172.1\|3732437_3733043_-	hypothetical protein	NA	NA	NA	NA
WP_004539634.1\|3733039_3733375_-	hypothetical protein	NA	NA	NA	NA
WP_128972336.1\|3733426_3733615_-	NlpBDapX lipoprotein	NA	NA	NA	NA
WP_004555253.1\|3733749_3734238_-	hypothetical protein	NA	NA	NA	NA
WP_004555254.1\|3734191_3734692_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_024430958.1\|3734808_3735018_+	hypothetical protein	NA	NA	NA	NA
WP_009944042.1\|3735104_3735635_+	hypothetical protein	C7BGG0	Burkholderia_phage	4.4e-29	46.8
WP_024464805.1\|3735648_3736002_+	hypothetical protein	NA	NA	NA	NA
WP_004539945.1\|3736308_3736779_+	hypothetical protein	NA	NA	NA	NA
WP_004540079.1\|3736898_3739391_+	virulence protein E	A0A2D1GN57	Marinobacter_phage	3.6e-97	41.8
WP_020850498.1\|3739600_3740188_+	hypothetical protein	NA	NA	NA	NA
WP_041188588.1\|3740535_3740910_+	hypothetical protein	NA	NA	NA	NA
WP_020850524.1\|3741276_3741846_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004552756.1\|3741808_3743794_+\|terminase	phage terminase large subunit family protein	A0A2D1GMT1	Marinobacter_phage	2.1e-180	53.4
WP_004533700.1\|3743804_3744011_+	hypothetical protein	NA	NA	NA	NA
WP_020850457.1\|3744007_3745501_+\|portal	phage portal protein	A0A2H4JFL5	uncultured_Caudovirales_phage	4.4e-135	51.2
WP_004540078.1\|3745497_3746577_+\|protease	Clp protease ClpP	A0A2H4JDI2	uncultured_Caudovirales_phage	1.6e-46	37.1
WP_004539732.1\|3746603_3746948_+\|head	head decoration protein	NA	NA	NA	NA
WP_080002857.1\|3746982_3748008_+\|capsid	major capsid protein	A0A2H4J890	uncultured_Caudovirales_phage	8.3e-109	58.8
WP_004539695.1\|3748011_3748302_+	hypothetical protein	NA	NA	NA	NA
WP_004539763.1\|3748303_3748834_+\|tail	phage tail protein	A0A2H4JBV1	uncultured_Caudovirales_phage	9.2e-11	28.0
WP_020850797.1\|3748823_3749357_+	hypothetical protein	Q9JML9	Wolbachia_phage	1.4e-22	39.5
WP_004539840.1\|3749359_3750040_+\|plate	phage baseplate assembly protein V	A0A1B2LRU5	Wolbachia_phage	1.2e-18	34.4
WP_004539700.1\|3750104_3750311_+	hypothetical protein	NA	NA	NA	NA
WP_004539881.1\|3750307_3750652_+	GPW/gp25 family protein	A0A2H4JA09	uncultured_Caudovirales_phage	3.0e-23	50.0
WP_004533630.1\|3750648_3751542_+\|plate	baseplate J/gp47 family protein	D5LGZ3	Escherichia_phage	1.9e-48	40.7
WP_004539949.1\|3751534_3752110_+\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	6.0e-32	47.7
WP_004539647.1\|3752097_3753561_+	hypothetical protein	A4JWL8	Burkholderia_virus	8.0e-214	77.8
WP_004539865.1\|3753576_3754029_+\|tail	tail assembly chaperone	A4JWL9	Burkholderia_virus	1.8e-44	76.8
WP_004539720.1\|3754094_3755264_+\|tail	phage tail sheath family protein	A0A2H4J869	uncultured_Caudovirales_phage	6.9e-160	72.9
WP_004540135.1\|3755274_3755778_+\|tail	phage major tail tube protein	Q7M2A5	Pseudomonas_phage	1.6e-41	50.6
WP_004533642.1\|3755847_3756150_+\|tail	phage tail assembly protein	V5YST8	Pseudomonas_phage	1.5e-05	37.2
WP_004539677.1\|3756237_3758652_+\|tail	phage tail tape measure protein	A0A2H4JG00	uncultured_Caudovirales_phage	6.4e-67	34.3
WP_004539752.1\|3758660_3759542_+\|tail	phage tail protein	A0A2H4J875	uncultured_Caudovirales_phage	3.9e-30	37.4
WP_004540041.1\|3759516_3759723_+\|tail	tail protein X	A0A2H4J9Z9	uncultured_Caudovirales_phage	4.0e-15	61.2
3759628:3759646	attR	NA	NA	NA	NA
WP_004539808.1\|3759732_3760785_+	phage late control protein	A0A2H4JBF6	uncultured_Caudovirales_phage	1.7e-77	44.5
WP_004533694.1\|3760860_3761055_+	hypothetical protein	NA	NA	NA	NA
WP_004539628.1\|3761047_3761545_+	lysozyme	A4JX20	Burkholderia_virus	2.2e-67	78.2
WP_004539940.1\|3761544_3762090_+\|lysis	lysis protein	Q8W6S5	Burkholderia_virus	6.4e-84	96.7
WP_004540080.1\|3762233_3763022_+	DNA adenine methylase	Q8W6S4	Burkholderia_virus	6.1e-152	97.7
WP_004539736.1\|3763062_3763773_-	immunity 52 family protein	A4PE26	Ralstonia_virus	1.4e-38	41.5
WP_012730038.1\|3763784_3764453_-	hypothetical protein	NA	NA	NA	NA
WP_004539924.1\|3764737_3765244_-	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	5.1e-19	39.4
WP_004539640.1\|3765240_3765666_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	4.9e-15	49.4
WP_020850431.1\|3766063_3766444_-	hypothetical protein	NA	NA	NA	NA
WP_004540114.1\|3766903_3767131_-	hypothetical protein	NA	NA	NA	NA
WP_133604798.1\|3767127_3767526_-	hypothetical protein	NA	NA	NA	NA
WP_004540053.1\|3768178_3768640_+	excisionase family DNA-binding protein	K4ICM4	Acidithiobacillus_phage	6.7e-50	67.3
WP_004539802.1\|3768644_3769220_+	PIN domain-containing protein	K4HZX4	Acidithiobacillus_phage	5.4e-73	70.4
WP_004540097.1\|3769405_3771622_+	ATP-binding protein	NA	NA	NA	NA
WP_004191077.1\|3772870_3773050_+	hypothetical protein	NA	NA	NA	NA
WP_004527347.1\|3773233_3773506_+	hypothetical protein	NA	NA	NA	NA
WP_004191664.1\|3773774_3774578_-	inositol monophosphatase	NA	NA	NA	NA
WP_004524745.1\|3774621_3774873_+	hypothetical protein	NA	NA	NA	NA
WP_004539789.1\|3774878_3775790_+	RNA methyltransferase	NA	NA	NA	NA
WP_004539737.1\|3775980_3776766_+	serine O-acetyltransferase	NA	NA	NA	NA
WP_020850718.1\|3777101_3777902_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_004193779.1\|3777926_3778418_-	peptidyl-prolyl cis-trans isomerase	A0A1V0SCU1	Indivirus	4.2e-10	33.3
WP_004191635.1\|3778498_3779074_-	peptidyl-prolyl cis-trans isomerase	A0A1V0SCU1	Indivirus	5.3e-12	39.3
WP_004195907.1\|3779130_3779853_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004192752.1\|3780084_3781482_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	1.8e-42	33.8
WP_004205123.1\|3781529_3782468_+	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004193249.1\|3782571_3783543_+	acetyl-CoA carboxylase carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_004538130.1\|3783586_3785056_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA

DBSCAN-SWA_9

3978101 : 3986294

Burkholderia_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004196630.1\|3978101_3978365_+	hypothetical protein	Q8W6S4	Burkholderia_virus	2.2e-26	85.5
WP_076839978.1\|3978348_3978534_+	hypothetical protein	Q8W6S4	Burkholderia_virus	5.8e-21	83.3
WP_009920998.1\|3978554_3979280_-	immunity 52 family protein	A4PE26	Ralstonia_virus	5.8e-32	44.0
WP_004539879.1\|3980229_3980736_-	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	1.3e-19	40.9
WP_004539795.1\|3980732_3981158_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	3.8e-15	49.4
WP_009937072.1\|3981438_3981834_-	hypothetical protein	NA	NA	NA	NA
WP_009919883.1\|3982085_3982313_+	hypothetical protein	Q8W6S4	Burkholderia_virus	4.2e-21	72.7
WP_004527234.1\|3982348_3982582_-	immunity 52 family protein	A4PE26	Ralstonia_virus	4.3e-13	60.6
WP_004550288.1\|3982657_3983119_-	avidin	NA	NA	NA	NA
WP_004193710.1\|3984057_3984240_+	hypothetical protein	NA	NA	NA	NA
WP_004193371.1\|3984366_3984990_-	phospholipase D family protein	NA	NA	NA	NA
WP_004539691.1\|3985184_3986294_-	class II histone deacetylase	A0A2K9L2T7	Tupanvirus	1.6e-36	31.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_021877

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_021877_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021877_1

2608739-2608901

Orphan

Consensus_repeat	Method
CACGACAGCACGACAGCACGACAGCAC	CRISPRCasFinder

2 spacers

csa3

The CRISPR arrays of NC_021877_1

>merge|NC_021877|1|2608739-2608901|CRISPRCasFinder
CACGAACACACGAACACGCGACCGCACGCCCACGCGCACACCCGACCACGCAATCGAGCAATCGAGCAATCGAGCAATCGAGCAATCGAGCAATCACACGACAGCACGACAGCACGACAGCACGACAGCACGACAGCACGACAGCACGACAGCACGACAGCAC

>NC_021877|1|1|2608739-2608901|CRISPRCasFinder
CACGAACACACGAACACGCGACCGCAC	GCCCACGCGCACACCCGACCACGCAATCGAGCAATCGAGCAATCGAGCAATCGAGCAATCG
AGCAATCACACGACAGCACGACAGCAC	GACAGCACGACAGCACGACAG
CACGACAGCACGACAGCACGACAGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_021877.1\|WP_004190530.1\|2620649_2620940_-\|H-NS-histone-family-protein	unknown	unknown	gnl\|CDD\|376390
NC_021877.1\|WP_004540372.1\|2616744_2619108_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|131764
NC_021877.1\|WP_004200624.1\|2621042_2621222_-\|hypothetical-protein	unknown	unknown	unknown
NC_021877.1\|WP_162473166.1\|2619649_2620543_+\|hypothetical-protein	unknown	unknown	unknown
NC_021877.1\|WP_020850371.1\|2601227_2601533_-\|hypothetical-protein	unknown	unknown	unknown
NC_021877.1\|WP_004190287.1\|2611498_2612347_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NC_021877.1\|WP_004190485.1\|2609210_2610134_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
NC_021877.1\|WP_004524797.1\|2598636_2599974_-\|D-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|235096
NC_021877.1\|WP_004266659.1\|2615597_2616149_+\|hypothetical-protein	unknown	unknown	unknown
NC_021877.1\|WP_004190404.1\|2612885_2613710_+\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NC_021877.1\|WP_004524788.1\|2607235_2608570_+\|MHS-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NC_021877.1\|WP_004540184.1\|2606384_2606783_-\|hypothetical-protein	unknown	unknown	unknown
NC_021877.1\|WP_020850092.1\|2614008_2615412_+\|indoleacetamide-hydrolase	unknown	unknown	gnl\|CDD\|236030
NC_021877.1\|WP_004540546.1\|2604771_2605893_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NC_021877.1\|WP_004540450.1\|2597471_2598386_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
NC_021877.1\|WP_004537427.1\|2603483_2604725_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NC_021877.1\|WP_004537687.1\|2601991_2602666_-\|metalloregulator-ArsR/SmtB-family-transcription-factor	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238089
NC_021877.1\|WP_004533130.1\|2610198_2611341_+\|alpha-hydroxy-acid-oxidizing-protein	unknown	unknown	gnl\|CDD\|376451
NC_021877.1\|WP_004540502.1\|2600070_2601012_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
NC_021877.1\|WP_004540436.1\|2602738_2603479_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293810

Protein	Function_ID	Function_description	E-value
NC_021877.1\|WP_020850092.1\|2614008_2615412_+\|indoleacetamide-hydrolase	gnl\|CDD\|236030	PRK07488, PRK07488, indoleacetamide hydrolase.	0
NC_021877.1\|WP_004190287.1\|2611498_2612347_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.00291e-102
NC_021877.1\|WP_004190485.1\|2609210_2610134_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	6.62225e-57
NC_021877.1\|WP_004524797.1\|2598636_2599974_-\|D-serine-ammonia-lyase	gnl\|CDD\|235096	PRK02991, PRK02991, D-serine dehydratase; Provisional.	0
NC_021877.1\|WP_004190530.1\|2620649_2620940_-\|H-NS-histone-family-protein	gnl\|CDD\|376390	pfam00816, Histone_HNS, H-NS histone family.	5.135e-20
NC_021877.1\|WP_004190404.1\|2612885_2613710_+\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	7.35336e-44
NC_021877.1\|WP_004524788.1\|2607235_2608570_+\|MHS-family-MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.12376e-146
NC_021877.1\|WP_004540372.1\|2616744_2619108_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|131764	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain. Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.	3.2039e-92
NC_021877.1\|WP_004540546.1\|2604771_2605893_+\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	3.12733e-166
NC_021877.1\|WP_004540450.1\|2597471_2598386_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	2.58941e-89
NC_021877.1\|WP_004537427.1\|2603483_2604725_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.56149e-43
NC_021877.1\|WP_004537687.1\|2601991_2602666_-\|metalloregulator-ArsR/SmtB-family-transcription-factor	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	4.56369e-23
NC_021877.1\|WP_004540436.1\|2602738_2603479_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.22709e-63
NC_021877.1\|WP_004540502.1\|2600070_2601012_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	2.40256e-75
NC_021877.1\|WP_004533130.1\|2610198_2611341_+\|alpha-hydroxy-acid-oxidizing-protein	gnl\|CDD\|376451	pfam01070, FMN_dh, FMN-dependent dehydrogenase.	3.69274e-171

>NC_021877.1|WP_004524788.1|2607235_2608570_+|MHS-family-MFS-transporter
MPTPTPGTPRPPRTPQPVRAALAAFIGTTVEFYDYYTYATAAALVLGDVFFPSDNPFVSTMASFATFFVGFVARPLSGAVFGHLGDRIGRKKMLVLTMFLMGAATTGIGLLPGYATIGVWAPVLLVLLRILQGIAVGGEWGGAVLMASEHASAGRRTLFASFPQMGSPAGLILSLLAFRYVTSLDHARFVAWGWRLPFLASFVLLLIGVAVRLGVNESPEFERVRDSHAVARFPVAEVLRTAWYPIVLAAAATTIGSAGFFFTNTFMISYVTTYLGMSKSFILDCLFAVTLIQLLSQPVSALLAQRFGETRFLVCAALLSMLTPYPMFVLVRTHDPVAIVAGIAFAVVALSAVYAVIAGFMSAAFPTRVRYSGISIAYQLCALVAGGTTPLVGTMIAQRYRGEWLPLALFFSLLAFVSLVGIVGLGRYRRNLHAVAPRAWAVNP
>NC_021877.1|WP_004540184.1|2606384_2606783_-|hypothetical-protein
MTPDGCSDGCRRRAVRGGVDGLGVSVLAAMHGMSLSIATFSKNGGAVTVSGGAGDGGDIGMPSSDVAEERAPPNEVFGGVFGVEEMAIDACRLPEMKWRNVERIWMKPVPLRVRSMRDRSAVRLAGGVRCVS
>NC_021877.1|WP_004540546.1|2604771_2605893_+|cysteine-desulfurase
MTHIYLDYNASTPIDPAVADAMRPLLPEAFGNPSSGHWASVPAKVALDRARAQVATLIGAAPDEIVFTSGGSEANNLALKGTVLASSNAGGHVITQSTEHPAILKPLQFLERLGTEVTCVPVDGNGRVDPDAIRRAITPRTTLITVMHANNETGTIQPIEDIGTIAREHGIRFHTDAAQSIGRIPADVDALGVDLLSIAGHKLYAPKGIGALYVRKGVGLEPLIHGAGHENGRRAGTESALLAAGFGEACALARDLAAMDGIRALRDRLWHALQDRFDDRVRLNGHLEYRLPNTVNVSFVGRVGADVLAALDGVAASTGSACHAGRMTLSPVLAAMGIAEQVGMGAIRFSHGRHTTADEIDTVVAKLSAIARG
>NC_021877.1|WP_004537427.1|2603483_2604725_+|MFS-transporter
MSKSTMPAGGVAIRLGLKENWRQFALLVLINAFVGGMVGIERTVVPLIGSETFHIQSTTLITSFIVSFGLVKAVANLISGQLADTWGRKRVLVAGWLLGLPVPFMIIAAPNWEWVIAANVLLGLSQGFAWSMTVIMKVDLVGPKARGLAVGLNEFAGYFAVGLTAFLTGYLASRHGLRPAPIYLGVAYAIAGLTLSILVVRDTRDHVCLEAGKPKEATSLSFHDVFLLASLKDRNLFAASQAGLINNLNDGMSWGIFPLFFTGLGLGVERIGILKAAYPIVWGVFQVVTGPLSDRWGRKGLIVAGMWVQAAGLVLTASMGEFRWWLVASVLLGLGTAMVYPSLIAAVSDASDPRWRARALSVYRFWRDLGYAIGALSAGLIADRFGFADAILSIAAVTFLSGAVVAIVMHARH
>NC_021877.1|WP_004540436.1|2602738_2603479_+|MBL-fold-metallo-hydrolase
MILRQFLHCEPVGISYLLGCGGKSTGVVVDAVAEPGTYLQAAADAGMKIDYVIDTHVHADHLSTGPALADAAGAAYVLSAKADVVLPFKGVEDGDEIRVGNVVIKVLETPGHTPEHISLLVTDRTRAEEPWLALTGHTLMIGDLGRTELAESAEAGARNLFRSVRTLKSLPDYLPLLPGAFAGSACGRGLSATPLSTIGFEKRHNAAFGIDDEAAFVRFMLSDMPPAPPEAARLRAANSGRNPDEI
>NC_021877.1|WP_004537687.1|2601991_2602666_-|metalloregulator-ArsR/SmtB-family-transcription-factor
MSSAGPKQEIYESLAEVAQAVGHPNRLELLEHLAQRERSVEDLTALSGMSFANTSRHLQILRRARLVDTERRGKNVVYRLAGDSEVVGLMKALGRLGERNVAEVNRVLGDYFHARDSMEPVSRNELTARLADGLVTLLDVRPHDEFAQGHLPGALNIPLAALEARLSELPADTEIVAYCRGPYCVLAFEAVAALRARGFKAARLEDGFPEWKAAGFVVETEPAN
>NC_021877.1|WP_020850371.1|2601227_2601533_-|hypothetical-protein
MITIITSFQLPAPLAREEARSLFLRAAPKHQGVVGLCANTMSCRKAEGRVYLWNARAQAETMYTDAWKASAYETFGAFPSITYFESPAVVDNATNAIFSDE
>NC_021877.1|WP_004540502.1|2600070_2601012_+|LysR-family-transcriptional-regulator
MDIKLDTPLLGALRCFEAAGRLGSFTKAADALHLTQSAISQQIRQLEARLGYPLFVRHARGLALTPKGGALHEATVAAFASLGRTLRQLSAPDTPLQVSCLPSFALQWLMPRLTEFHRLHPQTPVRLRAEFHAIDRETMSADDIDIAIRWDPFSYGALHVEPLFDESLVAAAAPAYLDRHPPRATAKWVSSVVPLHDASAWPEAPRYVEWRTWLDAVVPGYAGAPRGPEFNLASLAIAAAVAGQGVVVCRQALVDDEIARGRLVNVFARRVPAPAQYKAICARPEDARVKAFVGWLRAESDSYAARRQTQARP
>NC_021877.1|WP_004524797.1|2598636_2599974_-|D-serine-ammonia-lyase
MPVGRSLSLDPNLLAQLQSHSPTLWLNPHQGMPLPDFAPTAADLADADARLRRCAGLLAELFAELRPSGGLIASPLQPAEPLKRAARAGHAQAGAWYVKRDDALPVAGSIKARGGFHEVLALAESIAERHGLAGADTDRRALASGAARARFARHTVMVGSTGNLGLSIGMLASALGFRTVVHMSADAKAWKKARLRTRGVEVVEHAGDYAKAVDAGRRQAAGMPCCHFVDDEGSRMLFLGYATAAAELAAQLAQAGRPVDARHPLFVHLPCGVGGAPGGIVYGLKALYGEHVHAFVAEPTASPCVLVQLAGDAAHPRSVYDIGLDNRTEADGLAVAQASPLAAALLRAQAAGAFTVDDRQLFAHLLDARERLGIDLEPSAAAAFGGPAWIAGSDAGRAYLRGRGIDPDAATHVIWATGGSLVPAQEHRRFQAHARAQRQVGGAGA
>NC_021877.1|WP_004540450.1|2597471_2598386_+|LysR-family-transcriptional-regulator
MPARKPGRLPPLNALRAFEVSARHLNFRAAADEIGVTQGAVAQQVRHLEDVLGVALFERLPRGLALTADGFAYFADVRRALNLIGDATDRLAKRRANVTISTTPSFASRWLIPRLASFGDEHPGVDLRVIADSQFATFQGDGVDLAIRYGKPPFGKGLVTRLLFPVDIYAVCSPALLATPGALARARDLAGHALLHDAHDLWPEFLAALPERVAIDPAKGPRFNQSSLAIDAAIAGHGVALASDQLVARDIEAGRLRRLFDFALPLSVGYYIVRPSEPRRPGDIAQTEAWLIRQAQLDARRDGA
>NC_021877.1|WP_004190485.1|2609210_2610134_+|LysR-family-transcriptional-regulator
MNPSDLRDLRLPSLDGLLAFVAAARHGTFERAAEELCVTGSAVAKRVAALEQLLGVQLLVRSGKALTLTAAGNEYLHQVHAPLHLLAAVPLHRRNAGKTERLRICAPPTFARQILVARLDAFTLAHPGVELEVMLASPFPDAPPTGADLWIRGGGPIVSGATVLMVDALTPLAAPSLVERFAPLRRPADLAALPLLCTPLEPWTPWFRVAGLDWPEPANGPKLLDLGLLLEAAVSGQGVALGSPALARPWLAAGALVPLFPRIVRPAAPYYLMPYAPRAAAGAFAAWLADVCERAVRDGAEFLSRHG
>NC_021877.1|WP_004533130.1|2610198_2611341_+|alpha-hydroxy-acid-oxidizing-protein
MSVPITCIEDLRVLAKKRIPRMFYDYVDTGSYTESTYRANEADFRKIRLRQRVGVDISNRNLRTTMAGQDVAMPVALAPTGLVGMMRADGEILAARAARHFGVPFTLSTMSICSIEDIVAHVGGPFWFQLYMMRDRAFIERLIERASAAGCPALVLTMDLQIAGQRHKDVKNGLSAPPRITLPNLLDMMRKPGWCLGMARTRRRHFGNIVGHVKGVTDMWSLDSWTREQFDPTIGWRDAEWVRRRWNGKLIVKGVLDADDALRAADAGADAIVVSNHGGRQLDGAMSSVEALPAIVEAAGKRVEVWLDGGVRTGQDVLKAVALGARGTMIGRAFLYGVAALGEQGARRALELIARELDTTMALCGCTDIRSVNADVLARR
>NC_021877.1|WP_004190287.1|2611498_2612347_-|fumarylacetoacetate-hydrolase-family-protein
MKLLRYGPVGQEKPGLLDADGRIRDLSSLIDDVAGGALSDASLARLAAADPASLPLVAGEPRIGACVGRIGKFVCIGLNYADHAAEAGLAVPAEPVVFGKWTSAVSGPHDGIEIPRGSVKTDWEVELGVVIGRACKNVDEADALSHVAGYCVVNDVSEREWQIERGGQWDKGKGFDTFGPIGPWLVTRDEIADPQALDLWLDVDGRRYQSGNTRTMVFTVARLIAYLSRCMSLQPGDVISTGTPPGVGMGVKPSPVYLKPGQTVRCGVAGLGEQQQRTRAAA
>NC_021877.1|WP_004190404.1|2612885_2613710_+|IclR-family-transcriptional-regulator
MKPRKDAPAGAAQAPHDCEEIERYRAPALDKGLDILELLAEQKEGLTRTEITKELGRNASEIYRMLERLVARQYVIRSPGGDRYTLSLKLYSLAHRHPPLKRLIAEALPPMQRFADAAEQSCHLCVYDRGNLLVIAQVDGPGAWGISVRLGSRVGLVDTASGPVLLAFQTPEQRARMLVEHTKVEGEIALDMREFDALLHEIRATGRLRQKSRQAFGVTDIAYPVLGPSGHAIAALTCPYVRRIDTHAAPCAEDVDAQLRATARHLSMLKEAAA
>NC_021877.1|WP_020850092.1|2614008_2615412_+|indoleacetamide-hydrolase
MTSHRDTYVRSASVRAIADAVNGGRVRALEQAEAALERLALVEPLAAMTHVAPEIARRAAANVDAQIASGRRLPLAGVPFVIKDNLFTADMPTRAASPALLGFDATRNATAVQQLLDAGAVPLGKANMHELAFGITSANGYFGAVRNPHDPARIAGGSSGGTACAVAAGIAFGLGTDTGGSVRIPAAFCGVAGLRPTPRRYSTEGVLALSPTRDTVGPIAHGIDDLLLLDAVLTGDAGEPAPVALAGLRVGVPDAPYFDGLDPAVAELTERALAALTDAGARLIPLAAHALHEADEACGFPIAGFEALAYWRRFSAERLDLPFAEFVARLGSDDVRHLFRMLIDAPPSSDAYAAAIDVLQSTVRWYDQAFHRTGVDCIALPTVQCDAPLVTDSGHDLPSDAAYALFTRVIRQTGPATLGGVPSVSIPAGLSKHTGVPVGLMLEGPAGNDRRLLAIAREVERLLARAP
>NC_021877.1|WP_004266659.1|2615597_2616149_+|hypothetical-protein
MDVMAKLLTDLEFQRFSELQQKQASFTITPEEADELRDIVARAQKKRDDRASAMRAIEAYIAQFDITPDELFSPEQIGEAARTYGLIAAGKKERSLPPSLTFNGKPYQWTKTLPDEVRLPLFDAFKAGESIKRFIAMPKDAARCALTVARLERETGAVYADTLLDELAISRKHVEEAAAKLAA
>NC_021877.1|WP_004540372.1|2616744_2619108_-|GNAT-family-N-acetyltransferase
MTVRNLDALFHPTSVAVVGASPRPGSVGAMVWACVLDGRFGGAIWPVNPKYGELNGHKVYPYVDQLPSAPSVALICTPPATWPGIVRKLGGLGVRAAIIIGEARSGADRAALERALAAAKPYLLRVVGPGSLGVVSPALGAHFGAPACIVKAGGVAWVSQSNALTNAVLGWAHARGLGFSHAVALGGEADVDAADVLDYLASDAETRAILLELDTVKSARKFMSAARAAARNKPVLALRAGRGDSGDLLYTAAFQRAGMVRVDALDDLLDEIEALGVGRAAATSGGVTLVTSDRGVAKLAVDALAAAGETLAQWPRAAVDEVGGALPAGIVAGNPLLLGDDARPEYFGAALKALAQHPPTGTVFVVHATSHSAPAVDVARVLIESRKFARRGMLACFFGGVDAATRDALHVHGIPVHTTPQRLARAHARLVDYQLGRELLMQTPEGTPPQPAASISAARHTARAALAQGRDGFEGDAALEWLAGFGIERATDADVDMGDTIVDITVGMYDDPNFGPVFRYSVPPADGVSAPFVVYGLPPFNTVLARAVVARSPYAHRAPPEPLLQALTALSQAVCDVREIVEMSLVLRVRPTRVVALGPHIRLATGRSRLAIVPYPRYLEQQLDWRGERITVRPIRPEDEAAHRELLSAMTPDDLRMRFFGAIRNFDHSQIARMTQIDYDREMALIATLDDADGRAHTLGAVRAVTDPDNEATEFAIAVRPDQKGKGLGRMLMTRIIDYARSRGTAWMIGEALRENTAMISLAKDSGFAVSSTEEPGVVAFRLKLQP
>NC_021877.1|WP_162473166.1|2619649_2620543_+|hypothetical-protein
MLKRPSRNIGPAGSGIENGGPANSMHCPIAGNRRAGQKISVQSSERRGPSLTRFEFNAQCHCAISVKYENNGDARRECRANLRSRPRTEAPLAIPLPPPLRQASKLREPAWQAVEERLFGENSGISFMPAPVRRDSIAARMRKLSRKCRLHGFAVHVRWLFPPPGWPIRTDKWRYHALSARRRFSGIAVEHALAARIECETARRKRRGDTRHAPPKVSVFGSQGEAIRDWVSSFGEIARLPRQNRKRRYKWMRRRETFGSIRQVRIDGRSARHPPERIGFIAESTHNPLRREIAGPP
>NC_021877.1|WP_004190530.1|2620649_2620940_-|H-NS-histone-family-protein
MATYRQLTAQLEKLQQKIDKEREKAITDAIADIKAKIEEYDITPEELGFRSVKAAAKPKRALPPKYLNPKTGETWSGRGRAPAWLGKNRNRFLIKD
>NC_021877.1|WP_004200624.1|2621042_2621222_-|hypothetical-protein
MFTSDGRATTMVQCPEGGPWDTCIQNARGICGGDFDTIKQSVDNGARNLLFACKARNGF

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Crispr_ID: NC_021877_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021877_2

2802757-2802842

Orphan

Consensus_repeat	Method
CGGAATGCCCGATCATCGGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021877_2

>merge|NC_021877|2|2802757-2802842|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGC

>NC_021877|2|2|2802757-2802842|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGC	CTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGC
CGGAATACCCGATCATCGGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_021877.1\|WP_004529498.1\|2814124_2814559_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NC_021877.1\|WP_004187469.1\|2801661_2802057_-\|TraR/DksA-C4-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|224648
NC_021877.1\|WP_004523279.1\|2809178_2810210_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|236122
NC_021877.1\|WP_020850285.1\|2799255_2801529_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NC_021877.1\|WP_004529483.1\|2793311_2793752_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NC_021877.1\|WP_004523291.1\|2795500_2796436_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NC_021877.1\|WP_020850032.1\|2797307_2798966_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NC_021877.1\|WP_004542024.1\|2816172_2817978_-\|fatty-acid--CoA-ligase	unknown	unknown	gnl\|CDD\|235730
NC_021877.1\|WP_004542004.1\|2796451_2797042_+\|hypothetical-protein	unknown	unknown	unknown
NC_021877.1\|WP_004536976.1\|2806814_2808626_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl\|CDD\|225098
NC_021877.1\|WP_004552281.1\|2813403_2814057_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NC_021877.1\|WP_041188423.1\|2789776_2790820_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NC_021877.1\|WP_004541915.1\|2804898_2806740_+\|ribonucleotide-reductase	unknown	unknown	gnl\|CDD\|180772
NC_021877.1\|WP_004541900.1\|2788323_2789775_-\|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl\|CDD\|237001
NC_021877.1\|WP_004523292.1\|2790825_2792058_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	unknown	unknown	gnl\|CDD\|223997
NC_021877.1\|WP_161956516.1\|2814965_2816105_-\|porin	unknown	unknown	gnl\|CDD\|238208
NC_021877.1\|WP_004200700.1\|2794086_2795202_-\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|378454
NC_021877.1\|WP_004542030.1\|2803417_2804683_+\|polyhydroxyalkanoate-depolymerase	unknown	unknown	gnl\|CDD\|130908
NC_021877.1\|WP_004541936.1\|2810206_2812039_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223732
NC_021877.1\|WP_004530663.1\|2812500_2812950_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341411

Protein	Function_ID	Function_description	E-value
NC_021877.1\|WP_004529498.1\|2814124_2814559_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	9.00264e-33
NC_021877.1\|WP_004187469.1\|2801661_2802057_-\|TraR/DksA-C4-type-zinc-finger-protein	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.7869e-14
NC_021877.1\|WP_004523279.1\|2809178_2810210_+\|nitroreductase-family-protein	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	3.7258e-30
NC_021877.1\|WP_020850285.1\|2799255_2801529_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	4.92098e-57
NC_021877.1\|WP_004529483.1\|2793311_2793752_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	1.19676e-25
NC_021877.1\|WP_004523291.1\|2795500_2796436_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.07132e-61
NC_021877.1\|WP_020850032.1\|2797307_2798966_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	5.49793e-37
NC_021877.1\|WP_004542030.1\|2803417_2804683_+\|polyhydroxyalkanoate-depolymerase	gnl\|CDD\|130908	TIGR01849, unnamed_protein_product, polyhydroxyalkanoate depolymerase, intracellular. This model represents an intracellular depolymerase for polyhydroxyalkanoate (PHA), a carbon and energy storing polyester that accumulates in granules in many bacterial species when carbon sources are abundant but other nutrients are limiting. This family is named for PHAs generally, rather than polyhydroxybutyrate (PHB) specificially as in Ralstonia eutropha H16, to avoid overcalling chemical specificity in other species. Note that this family lacks the classic GXSXG lipase motif and instead shows weak similarity to some [Fatty acid and phospholipid metabolism, Degradation].	2.48008e-114
NC_021877.1\|WP_004536976.1\|2806814_2808626_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl\|CDD\|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	2.74988e-74
NC_021877.1\|WP_004552281.1\|2813403_2814057_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	4.23582e-20
NC_021877.1\|WP_041188423.1\|2789776_2790820_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NC_021877.1\|WP_004541915.1\|2804898_2806740_+\|ribonucleotide-reductase	gnl\|CDD\|180772	PRK06948, PRK06948, ribonucleotide reductase-like protein; Provisional.	0
NC_021877.1\|WP_004541900.1\|2788323_2789775_-\|2-oxo-acid-dehydrogenase-subunit-E2	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	2.33754e-132
NC_021877.1\|WP_004523292.1\|2790825_2792058_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	5.32689e-143
NC_021877.1\|WP_161956516.1\|2814965_2816105_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	2.50846e-54
NC_021877.1\|WP_004200700.1\|2794086_2795202_-\|SRPBCC-family-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.16274e-11
NC_021877.1\|WP_004542024.1\|2816172_2817978_-\|fatty-acid--CoA-ligase	gnl\|CDD\|235730	PRK06187, PRK06187, long-chain-fatty-acid--CoA ligase; Validated.	0
NC_021877.1\|WP_004541936.1\|2810206_2812039_+\|STAS-domain-containing-protein	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	2.72698e-107
NC_021877.1\|WP_004530663.1\|2812500_2812950_-\|CBS-domain-containing-protein	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	3.14402e-50

>NC_021877.1|WP_004187469.1|2801661_2802057_-|TraR/DksA-C4-type-zinc-finger-protein
MAAFDEHQLQVLGALLRACRQALQADVRAGERQRADEPYANLAGPAPDEGDEANADLFVDVDHALLGMKLAELRDVDAALQRIARRDYGCCADCGQPIAYERLLARPTALRCAPCQRAHERRFATQPRPSL
>NC_021877.1|WP_020850285.1|2799255_2801529_-|FAD-dependent-oxidoreductase
MREFGYLLVGGGIASVTAARTLRGEDASASIAILCGEPVLPYQRPPLSQEWLMGAVQPASITLHDAAFYAAQRIDIALGVRAEQLDRAKRIVRTSSGATFRYGKLLIATGASAKAPALPGFGLDGVHVLHTFAQAQALKDAAAHARRATVLGGGFLGVEIAATLQALGLQVTLVERAPGVMPSLRAPALGGHFEALCRARGIDVLTRCEVRRVLGAQCVEAVETSDGGTRPCDLFVAAVGVTPNCGWLDGSGLALGDGVEVDAFLQTADPNVFAAGDVAHFDDPIFGVRRRIEHWDNAVRQGRIAARNMLGHRLPYRDVSIFYGSVFGLSYNLLGYPVGATETIERGAFDEASYMQLYLADDVLRAAFTIDRPAVEIAALNDAIRLHVNVAAHKMKLSDPNYPLDKLPVQTILILQGGGALGAFECGAVKALEQHGVCPDVISAVSIGAFNGAIVASHPKGATKALEAFWRELSIALPLPYESQWREAWLSSYVLSFGVPNFLKPQWSQLGFDADRLRAKWTSFFDATAIEQLIARYVDFDSLGMSPTRLLIGAVDVETGEPRIFDSYVDRLSPAHVLASGSLPPGMPWTVVDGRPYWDGGVVSNSPLDLVIARCGQIGGRVFIVDLFSGSKALPTNLVEVMLRREEIAYMDRVRNDLRFEEYASDFRDLVDGILAHVDAPSANEIRQQPLYIRLMGNRAAIDIARITLNREGRLSFIEDYDFSSDAIAQLQQQGYDAALVALANGRSRRRRGRRRA
>NC_021877.1|WP_020850032.1|2797307_2798966_+|GMC-family-oxidoreductase
MKQQSYDYDYVVVGSGFGGSVSALRLSEKGYRVLVIEQGRRWTPENLPESTWNLSRWQWRPALGLRGFFSMRFFRHVVVLHGNAVGGGSITYANTLLVPPDKVWREGTWAGLEDWERVMPAHYATAKRMLGVVTNRRMDAADFRLKDMAKLIGVEKSFYPTEVGVFFGDDADAPGTRYADPYFGGAGPERTSCIGCGGCMVGCRHGAKNTLDRNYLYLAERLGAQVREQTKVVDVRPLDARADGAAGYAVEAVSLAAGARGAKSRLTCRGVVFAASSLGTQDLLMRLKEKGSLPRLSDALGKRVRTNAESLIGVRFPKSRVDLSKGVAIGSGIYIDEHTHIEATRYPSGSDTMGLLTTVLTRGAPGGLRVLVWLGALAKLVLTRPLSAWQMIVPRGFARETMIFLCMQTLEGHLTMRLKRRWFWPFSKQLATSGAKIPAYIPAANDFAQKAARALGGVPMTSLTEILLNVPMTAHCMGGAAMARDARDGVCDGRSRVFGYRNMYVCDGSVLGANLGVNPSLTITALAEHAMSHVPAAREQRWDSTAETPVAA
>NC_021877.1|WP_004542004.1|2796451_2797042_+|hypothetical-protein
MCRARGIGRQARGNATAPSPIAAAAIGARPRSAPRGPRISDAGRLAAARSAFAIHQERRKRNADRHGTHPYDADSRAAPREAPRFEHEPKKQRDAAQHEVDRDRAAREIRERIEHKARPDVRRAERPISQDVAQTPIGAAGAISPSTAHSIFLEIGLALAGRPIQVRRNRAPFTHGTPRRRPARGPTARTASPAPV
>NC_021877.1|WP_004523291.1|2795500_2796436_+|LysR-family-transcriptional-regulator
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCDEHAPA
>NC_021877.1|WP_004200700.1|2794086_2795202_-|SRPBCC-family-protein
MTQDVTVFRARYRASVHPRYNAWLHGGFVLAYGCAAIAFFLKDVARVSAVQWASVPAAFLLFNWLEFTVHRHVGHVKRRFGAMFYRRHTGDHHSFFANEQIAYREARDWRVILFPAWLIVVFSLGLFALHAVLGRFDANVAGLFASTMLGGYLLYECVHACEHLPDAHPLAKWPWIRQMRVLHRVHHRDALMRSCNFDVIWPLMDWLHGTLRWSEAPGADMSTRMRHEIDIACAGADVLAYASDASRWPEWHPSSLRVDGPAGSLAAGSRFDEDVRAAGRVDRLHWDVVRNEPGVMWQARAANTAGSLRILLTYECSGGPRGARFVRTLHYHSPNPLLRLANALVMRGRVERESAYSLTLLKRRLEAARDA
>NC_021877.1|WP_004529483.1|2793311_2793752_+|SRPBCC-family-protein
MKQQRIEIAEEFDAPVHQVFRFFSEHENLKSIFSPAKIRRISDGEPARNGVGSAREMRVPGAPPFVETVTAYQENELIEYRITRGSPLRDHLGVMRFVPIDEHRTYFHYVITFEGKVPFVAPVVRHVLEGSIRRGLGKVATRRLWG
>NC_021877.1|WP_004523292.1|2790825_2792058_-|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha
MSQYGPLRLHVPEPTGRPGCKTDFSYLRLSPAGKVRKPPIDVAPADTSDLAYGLVRVLDEHGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHTLALERGDMCFPTYRQQGILMVREYPLVDMMCQLMSNERDPLKGRQLPVMYSTRDAGFFSISGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVVNNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPTLIEWVTYRAGPHSTSDDPTKYRPGDDWTNFPLGDPLERLKRHMIGIGVWSEQDHEDTKAALEAEVLAAQKEAERYGTLADEHVPNVASIFEDVYKEMPAHLRRQRQQLGV
>NC_021877.1|WP_041188423.1|2789776_2790820_-|alpha-ketoacid-dehydrogenase-subunit-beta
MTTASKEGPAAPPMTMIQALRSAMDVMLERDGNVVVFGQDVGYFGGVFRCTEGLQNKYGKSRVFDAPINEGGIVGAAVGMGAYGLRPVCEIQFADYFYPASDQIVSEAARLRYRSAAEFIAPLTIRMPCGGGIYGGQTHSQSPEAMFTQVCGLRTVMPSNPYDAKGLLISAIENDDPVIFLEPKRLYNGPFDGHHERPVTPWSKHPASLVPDGYYTVPLDSAAIVRAGGDVTVLTYGTTVHVSLAAAEETGIDAEVIDLRSLWPLDLDTIVESVRRTGRCVVVHEATRTCGFGAELIALVQEHCFHWLEAPVERVTGWDTPYPHAQEWAYFPGPNRVGDALRRAMEN
>NC_021877.1|WP_004541900.1|2788323_2789775_-|2-oxo-acid-dehydrogenase-subunit-E2
MGVHVIKMPDIGEGIAEVELGLWHVKVGDRVKEDQAIADVMTDKASVEIPSPVTGVVVALGGKEGDVLAVGSELVRLEVEGDGNHKAEPDGGARVAAAQPERVADTAHAHASAAAKSARGEHGAGHGRDDARAASSGTSSGASHTQHAEREARGHRESSEYREDRSVSRGASQTDVERGPASPPPARRPGERPLASPAVRKRAWDLGVELRYVHGTGEAGRILHEDLDAYLQGRGAAAQRARGGQAAYVERHDEEAVPVIGLRRKIAQRMQDAKRRIPHFSYVEEIDVTELEALRAELNRKYGDTRGRLTVLPLLARAMVIALREFPQINARYDDEAGVVTRHGAVHLGIATQSKAGLMVPVVRHAEARDPWSIAAEVARLADAARAGRAERDELSGSTITITSLGALGGIASTPVINSPEVGIVGVNRIVERPMFRGGAVVARKLMNLSSSFDHRVIDGMDAAEFIQAVRGLLEQPALLFVE
>NC_021877.1|WP_004542030.1|2803417_2804683_+|polyhydroxyalkanoate-depolymerase
MLYAWLEAQREFFRTCQPWAGAAQRAGAGARPAGWPTWGPMARAADAVPAPPSFAIASIEIDGAAVPVDECVVDDTPFCALRKFSRRLRGDAAARPAVFLCTPLAGHHAVMLRETVETILATRDVYVTDWRNARDVPLEAGAFGLDDYVCTLERFVAGAAGDGLHMMAVCQATVPALAAVALLAARDVHVTSVALLGGPVDTRSHPTLIDRFALEHDLDWFRRTAIDIVPPPYAGAGRRVYPGFIQHAAIIVAHPQRRASLESRYWAAWMTGDFAAAARCLREMNEYGAVLDMTERYFLDTIRVIFHERLLAQGRWSIGRRLVAPQRLTRTALCTIEGGRDDIAGAGQTHAAHALCDAVPDAVRERITEPDCDHYDLFLGPRWRRTIHPALDAFWTRAEAARAAAGEPRPTAERAERRIAH
>NC_021877.1|WP_004541915.1|2804898_2806740_+|ribonucleotide-reductase
MRTINKRTRTIAHADSFVRMIGDMDDQPICDAVFADRYALPGEHSRAQACARVARALALAEPMATRSGAARRFYRNLLNGAFGAGRIMARAGAAPDQTMASCFVHPIRAPAALTRFHPNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALPGADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGRERIGATSPCGAQPLPPYGSAMLGAIDLSRFVRNPFGAGGEPRFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYITSDLRHHAYAASAELAAERGAYPLCDRHAHLDALRAGPPLPHAVCHAIERDGLRHSHLTSFAPVIGVSLAFGDHCSPGIEPARAWIEHRPVRAGAAGAPGMRAENHAHRLFRSLRGERAALPDYFATDADVAPGERLAMRVALQPYVDAGIDNTLTLANHYSLEEVNALLFAAWRAKLKSVAIRRADLARDAQPSDDDGV
>NC_021877.1|WP_004536976.1|2806814_2808626_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MTTGAVAARRLPRRGTARGRRAPSRAFTIHGGDEMRRSRPPKPAKPAAVRRRPHGAARAHAIRGNGPQRRAVRERAARRLSRDIDAALRRASTYPHPAGPIVRIETHLSVVYLVGRFAYKRLKPFDFGFANFSELAARRRACEAELALNRPLAAPIYLAAGPLVRRARGLRLFGAGAAVDHVVRMRRFDERMLFSRLLARGALDAADIDAAATRLAAYHLHAPRDIPRRAYGSARELRRQLDDMLAPLARALGAALPASLRAWCVRRCDELAAHLDARRADGYVRACHGDLHLNNVVKRGRDALMFDCIDFDDALRWIDVINDLSFLLMDLHAHDRAALAHRLLNRWLDETGDFAGLAALPLYVAYRALVRALVATMRAGGDAAARAARIERARRYVDVAAHAARARRPCLLLCHGYSGSGKSVASRALADVSGAIRLSSDSERKRARPFAAVDARPLPASAYTPQQIDAQYERLRALARDVLRAGYTALVDATFLSHARRARFFALARELGVPVYVLDFHASRACLERRVDARAAARDDRSDAGAAVLATQRASADPLDADERARTIGFDTDVPLATLRSAGYWRPVLDALDAARVDAQATR
>NC_021877.1|WP_004523279.1|2809178_2810210_+|nitroreductase-family-protein
METSPLKTTTPEAIPPFDPSASVEDKLRLAIHYAILAPSSHNTQPWRFMVGDGSVMLCADRLRALSVVDPYDRELLISCGAALLNLRVALSRFGFAYVIDMFPSPSDPDVIALVRLDPHGYHDESLVPLFDAILERVTTRTPYANEAVPCDVQRALVDAGAAEGAEIACVDAPHALDEIAELIADADRLQFADPRFRRELANWVHPRRHDDGMPAFAAGVPALLDFATPVVASAIRTFDLGGGLAAMHHKLVDGSPLIVGISTASDDRDAWVAAGQALERVLLVAAAAGLTASYLNQPIEIDALRERLRPLLHVDAHPQLLLRIGRGPVVAHAPRRPLMDVVS
>NC_021877.1|WP_004541936.1|2810206_2812039_+|STAS-domain-containing-protein
MTERERAARGHNDARRGGGDSGGDDEAWRRWLPGIATLRTYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGASIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQHDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLVAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRHPGAALTRGLVAFRWDAPLFHANATIFRDHVRDAIAEAGAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>NC_021877.1|WP_004530663.1|2812500_2812950_-|CBS-domain-containing-protein
MNAAEICTREVVACRRTDTVLDAAHLMRDRHVGDLIVVDDAGHAHAPVGMLTDRDIVLSLIAKDVDPAALFVGEIMSAPAAVVHEHDSLWTIAQRMRLTGVRRMPVVNADGALVGMVSVDDLLASVAALFDEIASISRRQIHFEEKARD
>NC_021877.1|WP_004552281.1|2813403_2814057_+|SagB/ThcOx-family-dehydrogenase
MSDPELLTYQPIAVALPGPAEAGAPAVIDLPPPDLGAGLPLMSALSLRASTREFSSAALAPTTLGELLWAADGVNRPTTGGRTAPSAHAFNEIDVYAALPDGVYRYDAALHRLLLKHAVDARNLTGYQDFVGAAPLDLIYVVRMSRLLSMPKPLRETFSAVAAGAIAQNVALYCASTGLGCVVRGWINHRLLAEALSLNEDELPILAQTVGKPAAHP
>NC_021877.1|WP_004529498.1|2814124_2814559_-|Hsp20/alpha-crystallin-family-protein
MSNVTRYDPFSLEPVSDLFQGLFRPLRGIADADDEKLASMKIDVTENDQAYAVKAELPGVDKNDINVQIDGNTVSISAKVERNKELKEGERVIRRERYSGEFARTFSLANELDRDAASAQYQDGVLSLTLPKKASSEKKKLTIG
>NC_021877.1|WP_161956516.1|2814965_2816105_-|porin
MGDVMNAKSIAAAALAVAQAGLAHAQSSVTLYGALDAGVLWQNTSAASFSPTAPNTGAVVRFKDGGVYSSLWGIKGTEDLGGGYRVNFRLQGAFDGGTGKFGLSDAPGAVAAFNQIATLGVSGPFGTFNAGRQIVPMIYAMADTDVRAARFFGSVLTAWLGLNTAAGWPGNSTNAPIGALYDSDALVYQSPAFGGALLALEYAPGGVPGGVQRGARASIVLKYASNALNLAAVYYNGHDTNPAPGASATGLDNNRFVYVGAQYKLKDVAVSASYGNGRNPARGDRVNLDMFAFGLGYRVSPFFRVSSGVYYLKDRNRSANRSTSIVLGADYELSKHTTLYAQGGRVDNRGTMAQMLAYGQPVAPGLATTAAMLGMRHSF
>NC_021877.1|WP_004542024.1|2816172_2817978_-|fatty-acid--CoA-ligase
MHATDQHSALNAAPSAYVYPLLVGQLLTHARGADAGRQIVYRGDVRHSYAQFRERIGRLAGALAALGVGADATVAVMDWDSHRYLESYFAIPMMGATLFTVNVRLSPRQIAHTLRDARASVVVAHADFLPLLEQVRDALGDGTCVIIACDGGAMPATSLPLAGEYERLVAAADPDYPFADFDENARAVLFYTTGTTGDPKGVCYSHRQIVLHALATAAALGAARDGQRLHRDDVYMPITPMFHVMAWGMPYIAVMLGLKIVLPGRYRAHALLDLRQAERVTFSHCVPAVLQMLLDEARLRACDLSGWKMIVGGSALPASLCRAARARRIDVFAGYGMSETGPVVALAQLRGTEGGVDVHADEDAGIDADVGAGIDVDTDVDADINANAGANASDSSVTTAAAHADDETAKRCAAGWPPPLVELRVVDAAMRDVPRDGRTPGEIVLRGPALALGYRGNPQASAALWAGGYLHTQDVAVMHGDGAIRIVDRIKDVIKTGGEWVSSLELEGLLNDIAGIRESAVVGVPDARWGERPAAVVVCERDAPLAAQDVRARLLEHVAANRISRYAVPECERIVFVDALPKTSVGKIDKKSLRRLVERID

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Identity
NC_021877_1	1.2\|2608854\|21\|NC_021877\|CRISPRCasFinder	2608854-2608874	21	NC_021877.1	2608886-2608906	1.0
NC_021877_1	1.2\|2608854\|21\|NC_021877\|CRISPRCasFinder	2608854-2608874	21	NC_021877.1	2608894-2608914	1.0
NC_021877_1	1.2\|2608854\|21\|NC_021877\|CRISPRCasFinder	2608854-2608874	21	NC_021877.1	2608902-2608922	1.0

1. spacer 1.2|2608854|21|NC_021877|CRISPRCasFinder matches to position: 2608886-2608906, mismatch: 0, identity: 1.0

gacagcacgacagcacgacag	CRISPR spacer
gacagcacgacagcacgacag	Protospacer
*********************

2. spacer 1.2|2608854|21|NC_021877|CRISPRCasFinder matches to position: 2608894-2608914, mismatch: 0, identity: 1.0

gacagcacgacagcacgacag	CRISPR spacer
gacagcacgacagcacgacag	Protospacer
*********************

3. spacer 1.2|2608854|21|NC_021877|CRISPRCasFinder matches to position: 2608902-2608922, mismatch: 0, identity: 1.0

gacagcacgacagcacgacag	CRISPR spacer
gacagcacgacagcacgacag	Protospacer
*********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

259712 : 331228

Vibrio_phage(25.0%)

plate,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004525541.1\|259712_260480_-\|holin	phosphocholine cytidylyltransferase family protein	NA	NA	NA	NA
WP_004542630.1\|260518_261520_-	HpnL family protein	NA	NA	NA	NA
WP_004542606.1\|261516_262290_-	hypothetical protein	NA	NA	NA	NA
WP_004188272.1\|262286_262976_-	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_004188420.1\|263341_264856_+	acetyl-CoA hydrolase/transferase family protein	NA	NA	NA	NA
WP_004525545.1\|266565_267504_+	type VI secretion system ImpA family N-terminal domain-containing protein	NA	NA	NA	NA
WP_004202234.1\|267537_268086_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190846.1\|268088_269594_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004530039.1\|269737_270265_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004190879.1\|270344_270776_+	GPW/gp25 family protein	NA	NA	NA	NA
WP_004196180.1\|270789_272652_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004190851.1\|272648_273638_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004525547.1\|273640_276511_+	type VI secretion system ATPase TssH	A0A2I7REQ1	Vibrio_phage	2.4e-60	27.2
WP_004525548.1\|276501_278793_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004190563.1\|278958_281247_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004542632.1\|281250_283467_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004525550.1\|283466_284537_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004530790.1\|284539_285256_+	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004190606.1\|285298_285688_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004202226.1\|285693_286287_+	type VI secretion lipoprotein TssJ	NA	NA	NA	NA
WP_020850152.1\|286283_287645_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004525553.1\|287727_289386_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004525554.1\|289382_292886_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004190863.1\|292944_293304_+	hypothetical protein	NA	NA	NA	NA
WP_004190471.1\|293326_293752_+	hypothetical protein	NA	NA	NA	NA
WP_004536812.1\|294072_294348_+	hypothetical protein	NA	NA	NA	NA
WP_004524288.1\|294898_295798_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004542286.1\|295839_296130_-	hypothetical protein	NA	NA	NA	NA
WP_020850390.1\|296019_297339_+	glycosyltransferase	NA	NA	NA	NA
WP_004542407.1\|297335_298919_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_020850268.1\|299207_300203_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_004528656.1\|300498_302082_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004186853.1\|302574_303828_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004543122.1\|304360_306025_-	glycoside hydrolase family 32 protein	F8WPR5	Bacillus_phage	9.2e-57	31.6
WP_004186967.1\|306157_307642_-	glycoside hydrolase family 68 protein	NA	NA	NA	NA
WP_004530800.1\|307911_308928_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_004523135.1\|309381_310581_+	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	8.4e-12	27.2
WP_004198247.1\|310758_311784_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004543129.1\|312218_313493_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	9.0e-105	54.1
WP_004186989.1\|313565_314537_+	membrane dipeptidase	NA	NA	NA	NA
WP_004186987.1\|314687_315221_+	4-vinyl reductase	NA	NA	NA	NA
WP_004523137.1\|315281_317345_+	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_004186901.1\|317347_319273_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_004202150.1\|319277_320450_+	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_004530055.1\|320446_321232_+	drug:proton antiporter	NA	NA	NA	NA
WP_004543128.1\|321256_322525_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004543120.1\|322545_323691_+	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004186918.1\|323800_324664_+	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004530057.1\|324844_326500_+	APC family permease	NA	NA	NA	NA
WP_004186920.1\|326586_327462_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_021252052.1\|327605_328478_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004543140.1\|328640_330194_+\|holin	choline-sulfatase	NA	NA	NA	NA
WP_041188444.1\|330190_331228_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA

DBSCAN-SWA_2

1065273 : 1072034

Burkholderia_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006027262.1\|1065273_1065570_+	type II toxin-antitoxin system RelE/ParE family toxin	A4JWV2	Burkholderia_virus	5.6e-50	99.0
WP_004202809.1\|1065572_1065929_+	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.9e-42	100.0
WP_004542845.1\|1065972_1066122_-	hypothetical protein	A4JWV0	Burkholderia_virus	9.1e-09	96.3
WP_020850286.1\|1067118_1067601_-	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_041188525.1\|1067670_1068570_-	hypothetical protein	A0JC16	Ralstonia_phage	6.3e-36	39.1
WP_020850011.1\|1069071_1069656_-	hypothetical protein	A0A0K2QQ53	Ralstonia_phage	2.5e-09	53.1
WP_020850148.1\|1069755_1071132_-	type II/III secretion system protein	NA	NA	NA	NA
WP_020850003.1\|1071128_1072034_-	AAA family ATPase	Q6UAZ2	Ralstonia_phage	1.1e-27	37.2

DBSCAN-SWA_3

2049365 : 2131656

Leptospira_phage(18.18%)

portal,transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004540193.1\|2049365_2050343_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_024430891.1\|2050485_2051730_-	alginate lyase family protein	NA	NA	NA	NA
WP_152641030.1\|2051728_2052169_+\|transposase	transposase	NA	NA	NA	NA
WP_085966798.1\|2054009_2055109_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	9.1e-37	37.3
WP_144084137.1\|2058239_2058644_-	hypothetical protein	NA	NA	NA	NA
WP_071898245.1\|2058591_2059101_-	AAA family ATPase	NA	NA	NA	NA
WP_024429309.1\|2060823_2062053_-	DUF3443 family protein	NA	NA	NA	NA
WP_020850102.1\|2062079_2062559_-	DUF2844 domain-containing protein	NA	NA	NA	NA
WP_124518502.1\|2064778_2064880_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_004540565.1\|2064910_2065129_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_004540443.1\|2065576_2066290_-	response regulator transcription factor	NA	NA	NA	NA
WP_071898247.1\|2068481_2068982_-	hypothetical protein	NA	NA	NA	NA
WP_004540369.1\|2070099_2071521_-	Do family serine endopeptidase	A0A1B1IT49	uncultured_Mediterranean_phage	1.5e-20	28.5
WP_004540191.1\|2071860_2072703_-	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_004540242.1\|2072773_2073553_-	SapC family protein	NA	NA	NA	NA
WP_124518497.1\|2073562_2075893_-	hypothetical protein	NA	NA	NA	NA
WP_020849944.1\|2076017_2092313_-	putative bpaA	NA	NA	NA	NA
WP_043944145.1\|2092602_2092959_-	H-NS histone family protein	NA	NA	NA	NA
WP_085966799.1\|2094426_2095525_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.3e-55	43.0
WP_080002865.1\|2095658_2096270_-	MepB family protein	NA	NA	NA	NA
WP_020849899.1\|2097516_2098779_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.1e-33	31.7
WP_004190933.1\|2102900_2104943_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	4.2e-35	32.0
WP_004540553.1\|2105001_2105340_+	hypothetical protein	NA	NA	NA	NA
WP_004190679.1\|2105386_2107261_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.9e-67	36.2
WP_004190948.1\|2107355_2107802_-	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	8.8e-23	48.6
WP_004190342.1\|2107968_2108181_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_004540586.1\|2108260_2109484_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011204325.1\|2109629_2110670_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.7e-93	53.1
WP_004195713.1\|2111066_2111876_-	GTP cyclohydrolase I FolE2	NA	NA	NA	NA
WP_004540286.1\|2112026_2113931_-	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_004525142.1\|2114014_2114899_-	(2E,6E)-farnesyl diphosphate synthase	NA	NA	NA	NA
WP_004190549.1\|2114895_2115189_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_004190814.1\|2115458_2116565_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004190656.1\|2116712_2117582_+	sulfurtransferase	NA	NA	NA	NA
WP_004190499.1\|2117640_2118516_-	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_004529029.1\|2119079_2121029_+	membrane protein	NA	NA	NA	NA
WP_004190401.1\|2121250_2122633_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_004540200.1\|2122951_2125723_-	DNA polymerase I	S5M8J1	Bacillus_phage	6.4e-71	30.0
WP_004530319.1\|2125724_2126474_+	TIGR00730 family Rossman fold protein	A0A1D8KUT5	Synechococcus_phage	5.6e-22	37.8
WP_004529031.1\|2126891_2127176_+	hypothetical protein	NA	NA	NA	NA
WP_004540549.1\|2127835_2128327_+	DUF523 domain-containing protein	NA	NA	NA	NA
WP_004540321.1\|2128763_2129027_-	hypothetical protein	NA	NA	NA	NA
WP_004540326.1\|2129205_2130432_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_004553592.1\|2131368_2131656_+\|portal	phage portal protein	K4NZV0	Burkholderia_phage	1.7e-43	94.4

DBSCAN-SWA_4

2502762 : 2574069

Planktothrix_phage(14.29%)

plate,transposase,integrase

attL 2497390:2497409|attR 2577668:2577687

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2497390:2497409	attL	NA	NA	NA	NA
WP_004540471.1\|2502762_2504448_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_020850088.1\|2504897_2509466_-	RHS domain-containing protein	A0A2H4JFP5	uncultured_Caudovirales_phage	2.4e-22	34.3
WP_004524859.1\|2509479_2510748_-	hypothetical protein	NA	NA	NA	NA
WP_009935223.1\|2512683_2513130_-	hypothetical protein	NA	NA	NA	NA
WP_153260275.1\|2513108_2513699_-	hypothetical protein	NA	NA	NA	NA
WP_004540568.1\|2514283_2514883_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_004524853.1\|2514907_2515318_-	RidA family protein	NA	NA	NA	NA
WP_004524852.1\|2515432_2516542_-	asparaginase	NA	NA	NA	NA
WP_004557904.1\|2516722_2517355_+	PAS domain-containing protein	NA	NA	NA	NA
WP_004524850.1\|2518256_2518694_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_020849981.1\|2519930_2521004_-	porin	NA	NA	NA	NA
WP_004540527.1\|2521421_2522846_-	aldehyde dehydrogenase (NADP(+))	NA	NA	NA	NA
WP_011205727.1\|2523061_2524246_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_020850047.1\|2524256_2525144_-	aldose 1-epimerase	NA	NA	NA	NA
WP_004524844.1\|2525146_2525917_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_020850130.1\|2525931_2526795_-	sugar ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-13	25.4
WP_004524842.1\|2526791_2527760_-	ABC transporter permease	NA	NA	NA	NA
WP_004540209.1\|2527780_2528779_-	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004524840.1\|2528816_2530019_-	mandelate racemase/muconate lactonizing enzyme family protein	Q6A202	Oenococcus_phage	6.9e-46	31.9
WP_004557914.1\|2530029_2530743_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_004540362.1\|2530874_2531765_+	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_004540151.1\|2532205_2532802_-	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	6.0e-27	38.1
WP_020850197.1\|2533855_2535118_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.0e-32	31.5
WP_004540399.1\|2536294_2536642_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.1e-40	72.9
WP_004552577.1\|2536638_2537046_-\|transposase	transposase	A0A0P0ZCV4	Stx2-converting_phage	2.9e-12	37.3
WP_038733539.1\|2537478_2539512_-	hypothetical protein	NA	NA	NA	NA
WP_038733536.1\|2539752_2541924_-	alpha-galactosidase	NA	NA	NA	NA
WP_004524829.1\|2541928_2542780_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_004524828.1\|2542780_2543704_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_004540455.1\|2543765_2545007_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_020849913.1\|2545042_2546287_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	7.1e-22	32.8
WP_041188417.1\|2546329_2546968_-	hypothetical protein	NA	NA	NA	NA
WP_004536893.1\|2548740_2549895_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_004524822.1\|2551238_2551979_+	hypothetical protein	NA	NA	NA	NA
WP_024429920.1\|2552407_2552563_+	recombinase family protein	A0A286S1P7	Klebsiella_phage	1.8e-07	75.7
WP_020850165.1\|2552528_2553035_+	recombinase family protein	A0JC18	Ralstonia_phage	2.2e-17	51.7
WP_076847933.1\|2555321_2555888_-	suppressor of fused domain protein	NA	NA	NA	NA
WP_171820160.1\|2555889_2556372_-	hypothetical protein	NA	NA	NA	NA
WP_085966800.1\|2559025_2560206_-\|transposase	IS3-like element ISBps1 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.2e-60	42.9
WP_004540288.1\|2560832_2561984_+	hypothetical protein	NA	NA	NA	NA
WP_071811398.1\|2561994_2562282_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004540427.1\|2563289_2565221_-\|transposase	transposase	S5WIU1	Leptospira_phage	6.9e-32	50.4
WP_041188419.1\|2565150_2565861_-	hypothetical protein	NA	NA	NA	NA
WP_004203275.1\|2565876_2568081_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_004540478.1\|2568077_2570744_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	1.8e-78	30.7
WP_004540225.1\|2570722_2572201_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004524812.1\|2572197_2574069_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
2577668:2577687	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_021884

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_021877

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection