CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP013216	Streptococcus salivarius strain HSISS4 chromosome, complete genome	4 crisprs	RT,DEDDh,csa3,cas3,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas2,DinG,WYL	1	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP013216_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013216_1

944352-944453

Orphan

Consensus_repeat	Method
GTAGTTGAAGTTCCTGGTAAACCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP013216_1

>merge|NZ_CP013216|1|944352-944453|CRISPRCasFinder
GTAGTTGAAGTTCCTGGTAAACCACAAGAACCAACACCACCAACAGGTCCAACGGCACCAACGCCACCAACACCAAAAGTAGTTGAAGTTCCTGCTAAACCA

>NZ_CP013216|1|1|944352-944453|CRISPRCasFinder
GTAGTTGAAGTTCCTGGTAAACCA	CAAGAACCAACACCACCAACAGGTCCAACGGCACCAACGCCACCAACACCAAAA
GTAGTTGAAGTTCCTGCTAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013216.1\|WP_002885119.1\|931297_931978_+\|(d)CMP-kinase	unknown	unknown	gnl\|CDD\|234579
NZ_CP013216.1\|WP_037620311.1\|949549_950263_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|181323
NZ_CP013216.1\|WP_002884979.1\|950566_951277_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP013216.1\|WP_021144230.1\|944915_945596_+\|ribose-5-phosphate-isomerase-RpiA	unknown	unknown	gnl\|CDD\|234816
NZ_CP013216.1\|WP_037620309.1\|951617_953078_+\|LCP-family-protein	unknown	unknown	gnl\|CDD\|367673
NZ_CP013216.1\|WP_021144228.1\|946928_947474_+\|DUF1697-domain-containing-protein	unknown	unknown	gnl\|CDD\|226319
NZ_CP013216.1\|WP_021144235.1\|935065_936472_+\|dipeptidase-PepV	unknown	unknown	gnl\|CDD\|235988
NZ_CP013216.1\|WP_059749155.1\|948305_949553_+\|voltage-gated-chloride-channel	unknown	unknown	gnl\|CDD\|238505
NZ_CP013216.1\|WP_021144222.1\|953818_954511_+\|Tyrosine-protein-kinase-modulator-EpsC	unknown	unknown	gnl\|CDD\|130079
NZ_CP013216.1\|WP_002885090.1\|932963_933323_+\|50S-ribosomal-protein-L20	unknown	unknown	gnl\|CDD\|179959
NZ_CP013216.1\|WP_002890887.1\|953078_953810_+\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP013216.1\|WP_002885093.1\|932706_932907_+\|50S-ribosomal-protein-L35	unknown	unknown	gnl\|CDD\|234676
NZ_CP013216.1\|WP_021144229.1\|945715_946927_+\|phosphopentomutase	unknown	unknown	gnl\|CDD\|235430
NZ_CP013216.1\|WP_002885057.1\|934518_934704_-\|4-oxalocrotonate-tautomerase	unknown	unknown	gnl\|CDD\|179406
NZ_CP013216.1\|WP_037620533.1\|934231_934447_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013216.1\|WP_004182449.1\|947492_948302_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|236183
NZ_CP013216.1\|WP_002885108.1\|932137_932668_+\|translation-initiation-factor-IF-3	unknown	unknown	gnl\|CDD\|234582
NZ_CP013216.1\|WP_021144234.1\|936512_937097_+\|uracil-DNA-glycosylase-family-protein	unknown	unknown	gnl\|CDD\|381683
NZ_CP013216.1\|WP_021144238.1\|933366_933840_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP013216.1\|WP_021144233.1\|937470_941259_+\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	unknown	unknown	gnl\|CDD\|369832

Protein	Function_ID	Function_description	E-value
NZ_CP013216.1\|WP_002885119.1\|931297_931978_+\|(d)CMP-kinase	gnl\|CDD\|234579	PRK00023, cmk, (d)CMP kinase.	2.52494e-122
NZ_CP013216.1\|WP_037620311.1\|949549_950263_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|181323	PRK08250, PRK08250, glutamine amidotransferase; Provisional.	3.17004e-153
NZ_CP013216.1\|WP_002884979.1\|950566_951277_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	3.53772e-153
NZ_CP013216.1\|WP_021144230.1\|944915_945596_+\|ribose-5-phosphate-isomerase-RpiA	gnl\|CDD\|234816	PRK00702, PRK00702, ribose-5-phosphate isomerase RpiA.	1.32813e-116
NZ_CP013216.1\|WP_037620309.1\|951617_953078_+\|LCP-family-protein	gnl\|CDD\|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	4.71746e-57
NZ_CP013216.1\|WP_021144228.1\|946928_947474_+\|DUF1697-domain-containing-protein	gnl\|CDD\|226319	COG3797, COG3797, Uncharacterized protein conserved in bacteria [Function unknown].	1.70874e-42
NZ_CP013216.1\|WP_021144235.1\|935065_936472_+\|dipeptidase-PepV	gnl\|CDD\|235988	PRK07318, PRK07318, dipeptidase PepV; Reviewed.	0
NZ_CP013216.1\|WP_059749155.1\|948305_949553_+\|voltage-gated-chloride-channel	gnl\|CDD\|238505	cd01033, ClC_like, Putative ClC chloride channel. Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent gating mechanism. This superfamily lacks any structural or sequence similarity to other known ion channels and exhibit unique properties of ion permeation and gating. The voltage-dependent gating is conferred by the permeating anion itself, acting as the gating charge.	2.91941e-95
NZ_CP013216.1\|WP_021144222.1\|953818_954511_+\|Tyrosine-protein-kinase-modulator-EpsC	gnl\|CDD\|130079	TIGR01006, Capsular_polysaccharide_biosynthesis_protein_CapA, polysaccharide export protein, MPA1 family, Gram-positive type. This family contains members from Low GC Gram-positive bacteria; they are proposed to have a function in the export of complex polysaccharides. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.57068e-108
NZ_CP013216.1\|WP_002885090.1\|932963_933323_+\|50S-ribosomal-protein-L20	gnl\|CDD\|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	9.73934e-67
NZ_CP013216.1\|WP_002890887.1\|953078_953810_+\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.76857e-83
NZ_CP013216.1\|WP_002885093.1\|932706_932907_+\|50S-ribosomal-protein-L35	gnl\|CDD\|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	1.57471e-18
NZ_CP013216.1\|WP_021144229.1\|945715_946927_+\|phosphopentomutase	gnl\|CDD\|235430	PRK05362, PRK05362, phosphopentomutase; Provisional.	0
NZ_CP013216.1\|WP_002885057.1\|934518_934704_-\|4-oxalocrotonate-tautomerase	gnl\|CDD\|179406	PRK02289, PRK02289, 4-oxalocrotonate tautomerase; Provisional.	1.39222e-34
NZ_CP013216.1\|WP_004182449.1\|947492_948302_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|236183	PRK08202, PRK08202, purine nucleoside phosphorylase; Provisional.	1.11461e-166
NZ_CP013216.1\|WP_002885108.1\|932137_932668_+\|translation-initiation-factor-IF-3	gnl\|CDD\|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	7.00167e-87
NZ_CP013216.1\|WP_021144234.1\|936512_937097_+\|uracil-DNA-glycosylase-family-protein	gnl\|CDD\|381683	cd10033, UDG_like, uncharacterized family of the uracil-DNA glycosylase superfamily. Uracil-DNA glycosylases (UDGs) initiate repair of uracils in DNA. Uracil may arise from mis-incorporation of dUMP residues by DNA polymerase or via deamination of cytosine. Uracil in DNA mispaired with guanine is one of the major pro-mutagenic events, causing G:C->A:T mutations; thus, UDG is an essential enzyme for maintaining the integrity of genetic information. UDGs have been classified into various families on the basis of their substrate specificity, conserved motifs, and structural similarities. Although these families demonstrate different substrate specificities, often the function of one enzyme can be complemented by the other. UDG family 1 is the most efficient uracil-DNA glycosylase (UDG, also known as UNG) and shows a specificity for uracil in DNA. UDG family 2 includes thymine DNA glycosylase which removes uracil and thymine from G:U and G:T mismatches, and mismatch-specific uracil DNA glycosylase (MUG) which in Escherichia coli is highly specific to G:U mismatches but also repairs G:T mismatches at high enzyme concentration. UDG family 3 includes Human SMUG1 which can remove uracil and its oxidized pyrimidine derivatives from, single-stranded DNA and double-stranded DNA with a preference for single-stranded DNA. Pedobacter heparinus SMUG2, which is UDG family 3 SMUG1-like, displays catalytic activities towards DNA containing uracil or hypoxanthine/xanthine. UDG family 4 includes Thermotoga maritima TTUDGA, a robust UDG which like family 1, acts on double-stranded and single-stranded uracil-containing DNA. UDG family 5 (UDGb) includes Thermus thermophilus HB8 TTUDGB which acts on double-stranded uracil-containing DNA; it is a hypoxanthine DNA glycosylase acting on double-stranded hypoxanthine-containing DNA except for the C/I base pair, as well as a xanthine DNA glycosylase which acts on both double-stranded and single-stranded xanthine-containing DNA. UDG family 6 hypoxanthine-DNA glycosylase lacks any detectable UDG activity; it excises hypoxanthine. Other UDG families include one represented by Bradyrhizobium diazoefficiens Blr0248 which prefers single-stranded DNA and removes uracil, 5-hydroxymethyl-uracil or xanthine from it.	5.06927e-103
NZ_CP013216.1\|WP_021144238.1\|933366_933840_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.65499e-15
NZ_CP013216.1\|WP_021144233.1\|937470_941259_+\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	gnl\|CDD\|369832	pfam08363, GbpC, Glucan-binding protein C. This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.	6.53812e-22

>NZ_CP013216.1|WP_021144233.1|937470_941259_+|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein
MGRKDSQRFSIRKYSFGAASVLLGTTILAMGATGVHADEVSTSAATDTPLSASVLTDTAADPATTVDHSEKQVVSVKEEGNTTVTTSVVTTDSLEDAKTSAVKEGVEVEETAPQTHTSLEGAIADNQAQSKEINTVVSDYQKAKENHKKDVAEYDKAKAEYDAKVAEKAAADKANAASKAQYDTDQAAYEKGLAKYQADNKAYDVALKEYNAQKLTYDSKVAEKAAADAANAKSEADYKVQLAVYETAKKNYEAAMAQYTKDKAKYDAEKEAYDAKVAEKVRTEIENKAAQEQYEKDLATYNAAYEKYQTDLAAYKTAKAAYDAKVAEKAAADAANAEAKAKYDAEMVTYEAALSEYKTNKASYDAAIAEYNTKKAAYDAKVAEKTQAEITDKAAQEQYEKDLAAYNTAYEKYQTDLAAYKTAKAAYDAKVAEKATADKANAEAKAKYDAEMAVYNTAKAQYDKDLQEYQAKKAQYDKDKAAYDQLVAIKAEEDAAKAKYEVELAKYNVDLEQYGKDFATYQTKLAEYQTALAQYKDAKAAYDKYMNDNGFQDLKDVETVQDLTFQREGGAIHTINGISAYLTRDAQARLNTSNVHQYDSNKLEASDIVATSPWANNETEFIQIKEGDKFVVTYDNLNQSSMRENTDMHPIKRVIYRYEILSLPSNDGKGIAAVSSDPTVTLTVGASTDQNKPVKVAVDVEFYDGNGNKFDLTQHNAIVALNSLNHWTGASYVDSGDKPRALTVEAKDKDGNTVRGTWNPYADGSSMSIENNAVVVKNGTVDFGTADVTISAENPIKIVAQKATWNGSEFTVSEETVIDATSVNVSGAGNGHSIGTDEFTLDGKDDVIGSYTIDPTSGRIIFTPKKKFENVEHQESVNVGNNKYIPIPNSSVSYDSATKEVTSFKDNQYIEHGSIFNGESSATLEGWDNPSSPYLYYGGAGLKMADGHLVFTANGANAAGQPTVYWFAINSNVGIPKNPGEAPKEPTAPEEPKAPTPPTITLEVLPAVPTEPTPPTAPTAPTEPNYTVVTVDAEEPKAPTEPKAPTPPTPAVVEVPAEPSKPEEPKAPTPPTEPNYTVVTVDAEEPKAPTEPKAPTPPTPALVEVPVEPRKITAPVEPKAPTPPTPVVVEVPGEPTKPTPPTEPTAPTPPTMVTVNVPNKPVSPKELVAPKVKWHKNYLVERVTRPVPTTPPTPQKPKTPGTPTGPSVTPTSSVVDKQETARTNSAVLPETGDSNQKLASVTGLGLLSMALTGLWSARKRKH
>NZ_CP013216.1|WP_021144234.1|936512_937097_+|uracil-DNA-glycosylase-family-protein
METLEELTQAIMSDEQNKAFTEKGIKPLFTIPKTARINIVGQAPGIRAQESGLYWNDPSGDNLRDWMGVSREEFYESGMFAIVPMDFYFPGHGKSGDLPPRKGFADKWHEKVLALAPDIQLTILVGNYAQRYYLHQKSSAKLTDTVKHYKDYLPEFFPLVHPSPRNNIWQAKNPWFMEEVVPDLKALVKKILSQ
>NZ_CP013216.1|WP_021144235.1|935065_936472_+|dipeptidase-PepV
MTIDFRAEVDKRKDALMEDLFGLLRINSERDDSKVDDKHPFGPGPVKALEHFLALAERDGYKTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWDTAPYEPVIKDGKLYARGSSDDKGPTMACYYALKIIKELELPVSKRVRFIVGTDEESGWGDMEYYFAHNGLKDPDFGFSPDAEFPIINGEKGNITAYLHFEGQNDGDFSLVSFNGGLRENMVPESASADFTGPITLKELEAKLADFVSEQEVTGQVTEEAGVFHVTIHGKSAHGMMPQNGINGATYLALFLSQFDFQGNAKTYLDIIAETLHKDFFAEKTGLAYTDPKMGELTMNAGVFNFSKESEENTIALNFRYPQGVDTDSIKADLEKLEGPKAVSLSEHGHVPHYVPVDDPMVETLLSVYEKQTGLKGHEQIIGGGTFGRLLKRGVAYGAMFPGYVNTMHQANEFTEVEDLYRAAAIYAEAIYELIK
>NZ_CP013216.1|WP_002885057.1|934518_934704_-|4-oxalocrotonate-tautomerase
MPFVKIDLFEGRTEEQKIELAREVTEVVSRVAKAPKEAIHVFINDMPEGTYYPHGEMKKKN
>NZ_CP013216.1|WP_037620533.1|934231_934447_+|hypothetical-protein
MSLYGLVYNGQSVTFSSYGRAWLTNVIMALPLNFLVVGPISRFILGKLQKPLPGEEVVENFEDDDELPTII
>NZ_CP013216.1|WP_021144238.1|933366_933840_+|GNAT-family-N-acetyltransferase
MIRLARAEDIPRLQELLGQILLVHHYARPDVFKSEGSKYTDGELEAVINDPTKPIFVYEDEEGRILSHLFLMIKEVSDNNGPLKAVKTLFVDDLCVDKEARGQKLGEKLYQFALDYAKELGCYNLTLHVWNDNEGAVRFYERLGMKPRYTEMETILK
>NZ_CP013216.1|WP_002885090.1|932963_933323_+|50S-ribosomal-protein-L20
MARVKGGVVSRKRRKRVLKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARLNGLSYSQLMHGLKLAEIEVNRKMLADLAVNDAAAFTALADAAKAKLGK
>NZ_CP013216.1|WP_002885093.1|932706_932907_+|50S-ribosomal-protein-L35
MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHLRKASMVHSGDFKRIKSMLSQMR
>NZ_CP013216.1|WP_002885108.1|932137_932668_+|translation-initiation-factor-IF-3
MKIIAKKDLFINDEIRVREVRLVGLDGEQLGIKPLSEAQAIADDANVDLVLIQPQATPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEKTQDIAIIEQRAKMDGRQMFMQLAPIPDKK
>NZ_CP013216.1|WP_002885119.1|931297_931978_+|(d)CMP-kinase
MKDIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYLALQNGLTEENVPEILEQLSQHPISFGKAADGSQQVYVGDVDITHPIRDNQVTNNVSWVAAIPEVRQELVAQQQRIAQDGAIIMDGRDIGTVVLPDAELKIFLIASVDERAERRYKENIEKGIPADLETLKKEIAERDYKDSHRKVSPLKPAEDAITFDTTGVSIDGVVEFIQEKAKKIIDKG
>NZ_CP013216.1|WP_021144230.1|944915_945596_+|ribose-5-phosphate-isomerase-RpiA
MEELKKIAGVTAAKYVEDGMVVGLGTGSTAYFFVEEIGRRIKEEGLSVVGVTTSSQTTKQAEGLGIPLKAVDDIDSIDVTVDGADEVDPQLNGIKGGGGALLMEKIVATPTKEYIWVVDESKMVDQLGAFKLPVEVVQYGADRLYRVFESKGYKPSFRLTEQGDRFVTDMKNYIIDLDLGKIENPVVLGEELKAMTGVVDHGLFNGMVNKVIVAGKDGVKVVEVKA
>NZ_CP013216.1|WP_021144229.1|945715_946927_+|phosphopentomutase
MSKFNRMHLVVLDSVGIGAAPDANDFVNAGVPDGASDTLGHISKSVGLNVPNMAKLGLGNIPRETPLKTVPTESNPTGYATKLQEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIEDFGPRQMETGELIIYTSADPVLQIAAHEDVIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRTSNRRDLAVSPFEPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDNLIKAMTSEDFKHGFSFTNLVDFDALYGHRRDPHGYRDCLHEFDQRLPEIIAAMREDDLLMITADHGNDPTYAGTDHTREYIPFLAYSPSFKGNGLIPVGHFSDISATVAENFGVDKAMIGESFLDKLV
>NZ_CP013216.1|WP_021144228.1|946928_947474_+|DUF1697-domain-containing-protein
MKRYAFLVRGINVGGRHKVVMEEFCRELEELGMSHVSSYINSGNLFFDSTLMKEELLLVLERFLNKAYPFIKVFSLFTLEDYQNEVASLPKWWEDDFYRKDVLLFTERLDKNEMKKIINSLELKDEILHFGQLGVYWVKYDKSTYSQTAYHKKLLKTPFYPDITIRNARTFSKIGHFLRMK
>NZ_CP013216.1|WP_004182449.1|947492_948302_+|purine-nucleoside-phosphorylase
MSLLEKIRVTQAFLESKGIEKPEFGLILGSGLGELAEEVEDAVVIDYADIPNWGQSTVVGHAGKLVYGTLSGRKVLALQGRFHFYEGNPLEVVTFPVRVMKALGCEGVVVTNAAGGIGFGPGTLMAITDHINMTGQNPLIGENLDDFGPRFPDMSKAYTPEYRETAHKVADKLGIKLDDGVYIGVTGPTYETPAEIRAYKTLGADAVGMSTVPEVIVAAHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL
>NZ_CP013216.1|WP_059749155.1|948305_949553_+|voltage-gated-chloride-channel
MIARGIKPITSLPKSTRLSLAVFGTGIASGLVGILCHYLLEFIQILVFDNDKSNLLSQFNSVSPFRRFAVLLVVGVLASLFWYFLQRRVSLLSISKAKQLVGKKSPNFLGQSLHALMQVTIVGAGSSIGKEGAPRELGALFGGNLSKALHLDIVDRQLLIACGAGAGLAAVYQVPFASTLFVLETLGVAWKSKNIIIILVTTYLSAYCARPIVGKEAMYQVGKVSSDPASLIQVIVLVLVITPLAMMFSFLAKKASKSRITDKRILCTMPLSYVVLGGIAAFYPLIMGNGQVLAQWLFSGGVSAYLPLILVVKGLMVCLLLWAGSYGGTLTPSFTLGAGSGFLLTSCLEIFGLSLNPTLGMLLGATVFLGTTLDAPLTGIALVLGFTGQGGLVAVPLILASLLSRIIKNRWKKKQ
>NZ_CP013216.1|WP_037620311.1|949549_950263_+|type-1-glutamine-amidotransferase
MNIHFILHETFEVPGAYLKWAQDRGHNITSTKVYEEEVLPETVEGIDFLIVMGGPQSPDEDRQAFPYYDPEAEIAFMQKAIAADIYIVGVCLGAQLLSVAYGGEYEHSPEREIGVFPVTLTEAGLADEHIKGFGKTLNTGHWHGDMPGLTDNAVVLATSQGCPRQIVRFSPKHYAFQAHLEFDPEAIDLLIAADGEEHLRKQNKELLFVQTPEQLRANDYSEMNKKLYDFLDSLTQA
>NZ_CP013216.1|WP_002884979.1|950566_951277_+|purine-nucleoside-phosphorylase
MSIHIAAKQGEIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGERVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEDVHVRELVLAQAAATNSNIIRNDWPQYDFPQIASFDLLDKAYHIAKDLGMTTHVGNVLSSDVFYSNYFEKNIELGKWGVKAVEMEAAALYYLAAQHQVDALAIMTISDSLVNPDEDTTAEERQNTFTDMMKVGLETLIAD
>NZ_CP013216.1|WP_037620309.1|951617_953078_+|LCP-family-protein
MSSRTNRKQKRTSNRSWGMVNIGLTILYAILALVLLFTMFNYNFLSFRFLNIIITIGLLVVLAISIFLQKTKKSPLVTTVVLVIFSLVSLVGIFGFKQMIDITNRMNQTAAFSEVEMSIVVPKESDIKDVSQLTSVQAPTKVDKNNIETLMSALKKDKKVDVKVEDVASYQEAYDNLKSGKSKAMVLSGSYASLLESVDSNYASNLKTIYTYKIKKKNSNSAKQVDSKVFNIYISGIDTYGSISTVSRSDVNIIMTVNMNTHKILLTTTPRDAYVKIPGGGADQYDKLTHAGIYGVETSEQTLENLYGIKIDYYARINFTSFLKLIDQLGGVTVHNDQAFTSLHGKFDFPVGDIQMNSEQALGFVRERYSLDGGDNDRGKNQEKVISAIVNKLASLKSVSNFTSIVNNLQDSVQTNMSLDTINALANTQLDSGSKFTVTSQAVTGTGSTGQLTSYAMPNSSLYMMKLDDSSVASASQAIKNLMEEK
>NZ_CP013216.1|WP_002890887.1|953078_953810_+|tyrosine-protein-phosphatase
MIDVHSHIVFDVDDGPKTLEESLDLIGESYAQGVRTIVSTSHRRKGMFETPEDKIFANFSKVKEEAEALYPDLTICYGGELYYTSDIVEKLEKNLIPRMHNTQFALIEFSARTSWKEIHSGLSNVLRAGVTPIVAHIERYDALEENADRVREIINMGCYTQVNSSHVLKPKLFGDKDKVRKKRVRYFLEKNLVHMVASDMHNLGPRPPFMKDAYAIIEKTYGTRRARNLFIENPQTLLENQYI
>NZ_CP013216.1|WP_021144222.1|953818_954511_+|Tyrosine-protein-kinase-modulator-EpsC
MTQENTKRVEIDVLALLHKLWTKKVFILFTAFYVAVFAFLGTYFLIQPTYTSSTRIYVVNQANDGKNLSAQDLQAGTFLTKDYKEIITSNDVLSEVIKDEKLNMSEGELAKMISVNIPTDTRLISISVNAKTGQDAQTLANKVREVASEKIKNVTKVEDVTTLEEAKLPESPSSPNIKRNVLLGAVLGGFLAVVGVLVREILDDRIRRPEDVEDALGMTLLGIVPDTDKI

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Crispr_ID: NZ_CP013216_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013216_2

1063751-1064291

TypeIII

Consensus_repeat	Method
AGTTTTCGTCCCCTCTCGAGGTA	CRISPRCasFinder

7 spacers

cas6,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,csm6,cas2

The CRISPR arrays of NZ_CP013216_2

>merge|NZ_CP013216|2|1063751-1064291|CRISPRCasFinder
AGTTTCCGTCCCCTCGCGAGGCAGATAGGTTTATATCCCCAAGTTGCAGGAAAAATCACAGTGACACCAATTCAGCAGTTTCCGTCCCCTCTCGAGGTTATAGGTTTATATCAAAAAACGGTTAGAACAGTAAAAGCACATGTGAAAAAGTTTCCGTCCCCTCTCGAGGAACATAAGTTTATATCAATCGTTACCATCTTCAATCCGTAGCCTCGGCTCGCCGGTTTCCGTCCCCTTGCGAGGTATATAGGTTTATATCAAACTGTAAGATCGCTGGAGCTATCTAGTTTGATGGGAATTTCCGTCCCCTCCCGAGGTAAATAGGTTTATATCTTGAAGGTGGTATCCCTGGCATTCCAGAAGTACGTGAGTTGTTTCCGTCCCCTTGCGAGGTAGATAAGTTTATATCTAAATGCTAGAAAAATACACTAAAGTTTGGTTGACTGAGTTTTCGTCCCCTCTCGAGGTATATAGGGTTATATCCGAACCATCTAAACCAGAAGAACCAGAACCATCTAAGTTTCCGTCCCCTCTCGAGGTA

>NZ_CP013216|2|2|1063751-1064291|CRISPRCasFinder
AGTTTCCGTCCCCTCGCGAGGCA	GATAGGTTTATATCCCCAAGTTGCAGGAAAAATCACAGTGACACCAATTCAGC
AGTTTCCGTCCCCTCTCGAGGTT	ATAGGTTTATATCAAAAAACGGTTAGAACAGTAAAAGCACATGTGAAAA
AGTTTCCGTCCCCTCTCGAGGAA	CATAAGTTTATATCAATCGTTACCATCTTCAATCCGTAGCCTCGGCTCGCC
GGTTTCCGTCCCCTTGCGAGGTA	TATAGGTTTATATCAAACTGTAAGATCGCTGGAGCTATCTAGTTTGATGGG
AATTTCCGTCCCCTCCCGAGGTA	AATAGGTTTATATCTTGAAGGTGGTATCCCTGGCATTCCAGAAGTACGTGAGT
TGTTTCCGTCCCCTTGCGAGGTA	GATAAGTTTATATCTAAATGCTAGAAAAATACACTAAAGTTTGGTTGACTG
AGTTTTCGTCCCCTCTCGAGGTA	TATAGGGTTATATCCGAACCATCTAAACCAGAAGAACCAGAACCATCTA
AGTTTCCGTCCCCTCTCGAGGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013216.1\|WP_021144150.1\|1054727_1056014_-\|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|187830
NZ_CP013216.1\|WP_021144146.1\|1059162_1059825_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP013216.1\|WP_021144143.1\|1062459_1063191_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_CP013216.1\|WP_021144142.1\|1064405_1064735_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP013216.1\|WP_021144148.1\|1057185_1058259_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	gnl\|CDD\|187793
NZ_CP013216.1\|WP_004182503.1\|1053114_1053744_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771
NZ_CP013216.1\|WP_021144132.1\|1075206_1076547_+\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240543
NZ_CP013216.1\|WP_021146844.1\|1066844_1067648_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	unknown	unknown	gnl\|CDD\|234601
NZ_CP013216.1\|WP_021144137.1\|1067958_1068507_-\|DJ-1/PfpI-family-protein	unknown	unknown	gnl\|CDD\|153229
NZ_CP013216.1\|WP_021144134.1\|1071792_1073337_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274774
NZ_CP013216.1\|WP_021144144.1\|1060208_1062479_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP013216.1\|WP_002891007.1\|1074426_1075125_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP013216.1\|WP_021144139.1\|1065878_1066835_-\|dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235982
NZ_CP013216.1\|WP_021144135.1\|1069959_1071618_+\|fibronectin/fibrinogen-binding-protein	unknown	unknown	gnl\|CDD\|336217
NZ_CP013216.1\|WP_021144149.1\|1056028_1057189_-\|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|187830
NZ_CP013216.1\|WP_021144145.1\|1059824_1060205_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NZ_CP013216.1\|WP_021144133.1\|1073606_1074434_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP013216.1\|WP_021144147.1\|1058261_1059161_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|380071
NZ_CP013216.1\|WP_021144151.1\|1053831_1054527_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NZ_CP013216.1\|WP_021144136.1\|1068640_1069441_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368639

Protein	Function_ID	Function_description	E-value
NZ_CP013216.1\|WP_021144150.1\|1054727_1056014_-\|type-III-A-CRISPR-associated-protein-Csm6	gnl\|CDD\|187830	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems.	2.91813e-118
NZ_CP013216.1\|WP_021144146.1\|1059162_1059825_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.00975e-84
NZ_CP013216.1\|WP_021144143.1\|1062459_1063191_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.19593e-21
NZ_CP013216.1\|WP_021144142.1\|1064405_1064735_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.74319e-20
NZ_CP013216.1\|WP_021144148.1\|1057185_1058259_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	6.16053e-22
NZ_CP013216.1\|WP_004182503.1\|1053114_1053744_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	1.90168e-79
NZ_CP013216.1\|WP_021144132.1\|1075206_1076547_+\|MATE-family-efflux-transporter	gnl\|CDD\|240543	cd13138, MATE_yoeA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	3.73598e-114
NZ_CP013216.1\|WP_021146844.1\|1066844_1067648_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	gnl\|CDD\|234601	PRK00054, PRK00054, dihydroorotate dehydrogenase electron transfer subunit; Reviewed.	9.25447e-122
NZ_CP013216.1\|WP_021144137.1\|1067958_1068507_-\|DJ-1/PfpI-family-protein	gnl\|CDD\|153229	cd03135, GATase1_DJ-1, Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. DJ-1 is involved in multiple physiological processes including cancer, Parkinson's disease and male fertility. It is unclear how DJ-1 functions in these. DJ-1 has been shown to possess chaperone activity. DJ-1 is preferentially expressed in the testis and moderately in other tissues; it is induced together with genes involved in oxidative stress response. The Drosophila homologue (DJ-1A) plays an essential role in oxidative stress response and neuronal maintenance. Inhibition of DJ-1A function through RNAi, results in the cellular accumulation of reactive oxygen species, organismal hypersensitivity to oxidative stress, and dysfunction and degeneration of dopaminergic and photoreceptor neurons. DJ-1 has lacks enzymatic activity and the catalytic triad of typical GATase1 domains, however it does contain the highly conserved cysteine located at the nucelophile elbow region typical of these domains. This cysteine been proposed to be a site of regulation of DJ-1 activity by oxidation. DJ-1 is a dimeric enzyme.	8.50757e-70
NZ_CP013216.1\|WP_021144134.1\|1071792_1073337_+\|hypothetical-protein	gnl\|CDD\|274774	TIGR03766, hypothetical_protein_lp_2141, conserved hypothetical integral membrane protein. Models TIGR03110, TIGR03111, and TIGR03112 describe a three-gene system found in several Gram-positive bacteria, where TIGR03110 (XrtG) is distantly related to a putative transpeptidase, exosortase (TIGR02602). This model describes a small clade that correlates by both gene clustering and phyletic pattern, although imperfectly, to the three gene system. Both this narrow clade, and the larger set of full-length homologous integral membrane proteins, have an especially well-conserved region near the C-terminus with an invariant tyrosine. The function is unknown.	7.47418e-15
NZ_CP013216.1\|WP_021144144.1\|1060208_1062479_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NZ_CP013216.1\|WP_002891007.1\|1074426_1075125_+\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	0.000611738
NZ_CP013216.1\|WP_021144139.1\|1065878_1066835_-\|dihydroorotate-dehydrogenase	gnl\|CDD\|235982	PRK07259, PRK07259, dihydroorotate dehydrogenase.	4.04129e-171
NZ_CP013216.1\|WP_021144135.1\|1069959_1071618_+\|fibronectin/fibrinogen-binding-protein	gnl\|CDD\|336217	pfam05833, FbpA, Fibronectin-binding protein A N-terminus (FbpA). This family consists of the N-terminal region of the prokaryotic fibronectin-binding protein. Fibronectin binding is considered to be an important virulence factor in streptococcal infections. Fibronectin is a dimeric glycoprotein that is present in a soluble form in plasma and extracellular fluids; it is also present in a fibrillar form on cell surfaces. Both the soluble and cellular forms of fibronectin may be incorporated into the extracellular tissue matrix. While fibronectin has critical roles in eukaryotic cellular processes, such as adhesion, migration and differentiation, it is also a substrate for the attachment of bacteria. The binding of pathogenic Streptococcus pyogenes and Staphylococcus aureus to epithelial cells via fibronectin facilitates their internalisation and systemic spread within the host.	0
NZ_CP013216.1\|WP_021144149.1\|1056028_1057189_-\|type-III-A-CRISPR-associated-protein-Csm6	gnl\|CDD\|187830	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems.	2.73352e-85
NZ_CP013216.1\|WP_021144145.1\|1059824_1060205_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	4.37566e-21
NZ_CP013216.1\|WP_021144133.1\|1073606_1074434_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.2621e-84
NZ_CP013216.1\|WP_021144147.1\|1058261_1059161_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	6.76518e-38
NZ_CP013216.1\|WP_021144151.1\|1053831_1054527_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	1.04246e-139
NZ_CP013216.1\|WP_021144136.1\|1068640_1069441_-\|hypothetical-protein	gnl\|CDD\|368639	pfam05857, TraX, TraX protein. This family consists of several bacterial TraX proteins. TraX is responsible for the amino-terminal acetylation of F-pilin subunits.	1.45815e-12

>NZ_CP013216.1|WP_021144143.1|1062459_1063191_-|CRISPR-associated-endoribonuclease-Cas6
MKKLVFTFKRIDHPAQDLAVKFHGFLMEQLDSDYVDYLHQQQTNPYATKIIQGKENTQWVVHLLTDDLEAKAFMTLLQIKEVSLNDLPKLSVEKVEIQELGADKLLEIFNSEDNQTYFSIIFETPTGFKSQGSYVIFPTMRLIFQSLMQKYGRLVENQPEIEEDTLDYLSEHSTITNYRLETSYFRVHGQRIPAFRGRLTFKVQGAQTLKAYVRMLLTFGEYSGLGMKTSLGMGGIKLEERKD
>NZ_CP013216.1|WP_021144144.1|1060208_1062479_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MKKEKIDLFYGALLHDIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLGNDHLAYITYIADNIASGVDRRQSNEESDEEASAKIWDTYTNQADIFNVFGAQTDKRYFKPTVLNLKSEPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQAQIDSLLNLFEATLSFVPSSTNTKEIADISLAEHSRLTAAFALAIYDFLEDKGRHNYKEDLFTKASAFYEEEAFLLASFDLSGIQDFIYNIATSGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANLLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLFVAFGWGSFAAKDIMSELNSPESYRQVYQKASRMISEKKISRYDYQTLMLLNRGGKSSEKECDICHSVENLVSYHDQKVCDICRSLYQFSKEIAHDHFIITENEGLPIGPNAFLKGIAFEKLSQEDFSRVYVKNDYKAGTVKATHVFVGDYQYTTIDEYADLSKNENKLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRQNFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDQFIANVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKDDKDRKEAELALLLYIYEIRKD
>NZ_CP013216.1|WP_021144145.1|1059824_1060205_-|type-III-A-CRISPR-associated-protein-Csm2
MTILTDENYVDIAEKAILKLERNTRNRKNPDAFFLTTSKLRNLLSLTSTLFDESKVKEYDALLDRIAYLRVQFVYQAGREIAVKDLVEKAQILEALKEIKDRETLQRFCRYMEALVAYFKFYGGKD
>NZ_CP013216.1|WP_021144146.1|1059162_1059825_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MTFAKIKFSAQIRLETGLHIGGSDAFAAIGAIDSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKIGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTAEV
>NZ_CP013216.1|WP_021144147.1|1058261_1059161_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MTYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDDFTLTDAFPFQFGPFLPKPIGYPKHDQIDQSVDVKEVRRQAKLSKKLQFLALENLDDYLNGDLFENEEHAVIDTVTKNQPHKDGNLYQVATTRFSNDTSLYVIANESDLLNELMTSLQYSGLGGKRSSGYGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKLEV
>NZ_CP013216.1|WP_021144148.1|1057185_1058259_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MKNDYRTFRLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNQMIEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESDRNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAILVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGVLQKRYSRMKTKMVKKGVLKLTKAPLKTVKIPSGNHSLIKNHESFYEMGKANFMIKEIDK
>NZ_CP013216.1|WP_021144149.1|1056028_1057189_-|type-III-A-CRISPR-associated-protein-Csm6
MRVLISAVGDTDPFRNFHDGALIHIARKYRPEKVILIFSEHTAKKQGNIEKALFSIAPNYEPELIIHDSIICDNEVHIFDVMFQRFSDILQEYYTKEDEFILNLSSATPQIKSALFVINRLSGINVKAVQVSSPEHASNENIGHDNDENIDELIEVNEDNKVNFIDRTIEDNAEKFNQALLKKTARDFIEKYDYKAALDILDQLSDFPNLKSVRKEIRDIVGCLSKQDVPQGLRHKKFNEEEQKILSAYLTIELQRERGNVSESFIRIKNLTEFILEDYIEKRNPGLIDDYCESIQKYYLSLFDYSKLLKATREFKLRKTIAPIIEMNSSRNTVAHSLSPLDSDAVKQLGIAMKTLKTLVREQYHFSQSDFNFYQDLNKKLLNKLN
>NZ_CP013216.1|WP_021144150.1|1054727_1056014_-|type-III-A-CRISPR-associated-protein-Csm6
MKILISAVGTTDPISNDHDAALLHIARNYRPDKIVLVYSQEMLVKQDLINKVLLSIEGYNPIIEIDSTILNNEEVFLFDKMYEVMGLIVQKYTNDDDEIILNLSSGTPQIISALFALNRINDYNTQAIQVATPKKGANREYKPLTDSEIDALIVENQDNSLDFVDRSIKDKSEKFTQALVKRHLRSLIASFDYQAAEAIINRKEYNKLLSKKRIAYIREKLNDFSRVFKNQSILSDILSFPLEDSQKKALNYYLMIDVLKEREHIADVLIKAKSLAEFVIEETIKKDHEGLIVFDGNLPKLNPDFPDCEAILDDIDKKMKKSRGIEDTEERIFSVQSTLNLLSYLNILEFYEYDSQLQTAINGILSLNGERNKVAHGLSEIDTRLLSRKKLKQLSENLRLLLVDCLGIDSSYFNYYDKQNEELIKMLE
>NZ_CP013216.1|WP_021144151.1|1053831_1054527_-|orotidine-5'-phosphate-decarboxylase
MRENRPVIALDFPTFEDVKAFLAKFPADEKLYVKIGMELYYAAGPEIVRYVKELGHSVFLDLKLHDIPNTVKSAMRVLSSLGVDMTNVHAAGGVEMMKAAREGLGDGPILIAVTQLTSTSEEQMRDFQNIQTTLQESVVHYAKKTAEAGLDGVVCSAHEVAKIKEATNEDFVCLTPGIRPAGAAVGDQKRVMTPADARQIGSDYIVVGRPITQADDPVAAYRDIKAQWNGQ
>NZ_CP013216.1|WP_004182503.1|1053114_1053744_-|orotate-phosphoribosyltransferase
MTLASQIASDLLDIKAVYLKPEEPFTWASGIKSPIYTDNRITLSYPETRTLIENGFVEKIKEEFPEVEVIAGTATAGIPHGAIIADKMNLPFAYIRSKPKDHGAGNQIEGRVVKGEKMVVVEDLISTGGSVLDAVAAAEREGADVIGVVAIFTYELPKAEKNFADAGVKLVTLSNYTELIKVAKVQGYITADGLQLLKKFKENQETWQD
>NZ_CP013216.1|WP_021144142.1|1064405_1064735_-|CRISPR-associated-endonuclease-Cas2
MGLYFNLSEEEREFAKQKTMFCLIIYDIRSNKRRLKLSKLLEGYGVRVQKSCFEVDLSRNDYQSLLKDIESFYKADEEDSIIVYVTTKEEVTSFSPYHSAEKIDDILFF
>NZ_CP013216.1|WP_021144139.1|1065878_1066835_-|dihydroorotate-dehydrogenase
MSEIKSENRLAISLPGLDLKNPIIPASGCFGFGQEYAKYYDLDKLGSIMIKATTANPRFGNPTPRVAETPSGMLNAIGLQNPGVDAVLSEKLPWLQEHYPELPIIANVAGFSNEEYAEVSHKISQASNVKAIELNISCPNVDHGNNGLLIGQVPELAYAAVKASVSHSDVPVYVKLTPSVADITSVAKAVEDAGATGFTMINTLVGTRYDLATRKPIIANGQGGMSGPAVFPVALKLIRQVALASDLPIIGMGGVDSAEAAIEMFIAGASAIGVGTANFADPYACPKIIDRLPEVMDKYGITTLEDLREEVRTDLLGK
>NZ_CP013216.1|WP_021146844.1|1066844_1067648_-|dihydroorotate-dehydrogenase-electron-transfer-subunit
MTFCSLERVVMILVEDLTIVSQREIAPHIFEMVLKGEMVADMKVGQFVHLKVPDPSKLLRRPISISEIDYDKKEATIVYRVEREGTAILSKMVAGQTIDTMGPQGNGFDISVIEAGQKALLVGGGIGVPPLVETAKQLKAKGVEVVSVIGFANKDAVILEDKLKACGDVYVTTDDGSYGIMGYVSMVIDSFDWTPDAVYSCGAPGMLKYVDSKFENHPHAYVSMEARMACGMGACYACVVHVKGESDAKNLRVCEEGPVFPTGKVIV
>NZ_CP013216.1|WP_021144137.1|1067958_1068507_-|DJ-1/PfpI-family-protein
MTKVAVVFAEGFEEIEALSPVDVFRRAGFDCNMLGLESASVTGSHGIQVAMDGVFDGNFADYDLVVLPGGMPGSTNLRDNQALIVSLQDAAKAGKYVAAICAAPIVLERAGLLEGRKFTCFPGVEKQIASGEHQTDLVVVDGNIVTSRGAGTALAFAYALVDLLGGDGQQLAHTMVYDRLFK
>NZ_CP013216.1|WP_021144136.1|1068640_1069441_-|hypothetical-protein
MNDIKKICNATNLKYLAVALMFLDQIYQMFGSMGAPIWLTMLGRLSFPIFLFLAADSFYYTHDRMAFLRRLLYMSWFMIIGNAIIGSIFHNGSIGLTNNAFSTFFITGIYICSWDLLAKGLRDKSNKELIQGIGVFLLPILSSIPVVILSGIFETPHANPIVVQIVAFILSLVPSIIMVEGGFVMVILGLLFYIFRTNRMAQIIVLAVISVIAHLFDPTGVQWMMVFAAIPMYFYNGERGSGNKNFFYIFYPAHIYLLWILASLIR
>NZ_CP013216.1|WP_021144135.1|1069959_1071618_+|fibronectin/fibrinogen-binding-protein
MSFDGFFLHHMTTELREQVLYGRIQKVNQPFERELVLTIRNNRQNYKLLLSAHPVFGRIQTTKADLPNPQNPNTYTMIMRKYLQGAVIEDIQQLENDRVLEISVSNKNEIGDSVKVTLVMEIMGKHSNIILIDKNESKIIESIKHVGFSQNSYRTILPGSTYIAPPKTDAKNPFDIPDEKLFEILQTEELSARNLQKLFQGLGRDTANELSALLETDKLKNFRAFFNREVKPNLTAKAFSAVRFSDSQDQPEFETLSALLDYYYLDKAARDRVAQQASDLIHRVQNELEKNKKKLVKQEKELAATENAEEFRQKGELLTTYLSMVPNDKDSVELDNYYTGEKITIPLNVALTPNQNAQRYFKKYQKLKEAVKHLTSLIEETKQTIDYLESVEFSLSQANMDEIEDIREELVQAGFMKRRSTDKRHKRKKPEQYLASDGKTIIMVGRNNLQNEELTFKMAKKGELWFHAKDIPGSHVVIKDNLNPTDEVKTDAAELAAYYSKARLSNLVQVDMIDVKKLNKPTAGKPGFVTYTGQKTLRVTPTEEKIDSMRMK
>NZ_CP013216.1|WP_021144134.1|1071792_1073337_+|hypothetical-protein
MKALMSYTSSFLEWLGRYVGLLVFGLLFVTTLFIRTTMMTGYFEWAEISSVPWYVYVSGGAILLLTLLWPKILKELTTKQIFIFFSVCFVSFGLLLIFLTSFAGRDDAGTVFKGAVQFNAGDFSLIKPGAYFYRYPHQLGLLSFERLVLYLIPLPVISVFYILNLGMVIGMNYATWKITDELFSRPLVSRLAVIMSFGFLPLVFNIMFAYGLMYGLFFSSFAILFFLRYLRRGKARNAILSVVMLSLAYWVRSNNIILIIALSGILILMTLREKRYRYLLLVLAFFAFPMSLHKATTSYYEITTHQKIPGTPQVAWLAMGLQDKPDSKRMPGWYTGYVRDIYAKKKGNIEKIEKSANHLFDKRVQYLLAHPDEASWFFSTKFISSWTEGSFQSIWNGPSKDKFQPLWNRFATSIYHDGTLHLFFVTYMQGYLLVLYLGGVFYYAFTYKRMGDGATLGLYAFLYLFGGILFHLISETKSQYTLPYIYLQIPMIAAGYNHVTQILSRYLKNSRKSS
>NZ_CP013216.1|WP_021144133.1|1073606_1074434_+|ABC-transporter-ATP-binding-protein
MIKVDNLSKRFGNQVALDNISFEIKEGEIFGFLGPSGAGKTTTINILTGQLSQDSGKAYILNKESNQLLPSDFLNIGIMSDTVGFYGKMTVYKNLQFFAKYHNVSLDKLDVLLKELELFEDKDKKAEKLSTGMKQRMLLIRSILHHPKILFLDEPTSGLDPALSNKVHDILLNLKNEGTTIFLTTHDMSEATKICDRISLLNSGHILEYGSPQEIIDKYSQQDKAIIRFKNGDSIMVSQVEAAKYLGGSDVASVHTLENTLEDIFIKISEDSKNA
>NZ_CP013216.1|WP_002891007.1|1074426_1075125_+|ABC-transporter-permease
MHRLMALLWLRWEYLISNKVLLFVCVVTPFVDFAILQAIPMIHGEMYFLNMGLSLIYSMTAGTFTSMMISEEKEKKNLRTLILSGVTKYNYIISVISFPFIFSVLSALFMPVIFGIAIPSWLTYFVVVVLTTLAFILLNLSIGLFSKTQTHTTLFSMIVLIIATFLPMLSSDMSNKIMSYITRFSFIGANTEYFIKLEKFQIFESSVFALICWVVILIFISNFAFKWNAREH
>NZ_CP013216.1|WP_021144132.1|1075206_1076547_+|MATE-family-efflux-transporter
MKNASVDLLRGPILRSLLIFALPILISNIFQQLYNTADVMIVGRFLGPDALAAVGASSAIFDLVIGFALGVGNGMGVVIARYYGAKDFRKLRQSVAATVVIGLGLSALVMILGHFGLYPLLTFLGTPNSIIGQSYQYISMIVSCVGVTLGYNLCAGLLRAVGDSLTALYFLIFSALVNIVLDLFFITQLHLGVQSAGLATIISQGLSAILCLYYIKKKVTFLLPSNSDFVLDSSLYLDLFGQGMAMGLMNSIVSIGTVTLQYAINGFGPLIISAQVAARRIMSFAVLPLTSLAAGVTTFTSQNFGAKQFKRIVAGLKQSCLVSITWSVIACVLLYVASPFLADLISGSDNTVIIDNASRYLRISSLFYPILGMLFIFRNSLQGLGKKLTPLTSSFIELFGKILFVLLVIPSMGYLGVILCEPLIWIPMTIQLYFALRKHIKRLFVS

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Crispr_ID: NZ_CP013216_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013216_3

1494539-1494651

Orphan

Consensus_repeat	Method
GATTCTTGTGTACCCTTGGCTTCCAGTTTGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP013216_3

>merge|NZ_CP013216|3|1494539-1494651|CRISPRCasFinder
GATTCTTGTGTACCCTTGGCTTCCAGTTTGCCTGTGTACTCTGGATTTGTAGGTTGAACAAGGGCTTCGCCTTCATGACCGGATTCTTGTGTACCCTTAGCTTCCAGTTTGCC

>NZ_CP013216|3|3|1494539-1494651|CRISPRCasFinder
GATTCTTGTGTACCCTTGGCTTCCAGTTTGCC	TGTGTACTCTGGATTTGTAGGTTGAACAAGGGCTTCGCCTTCATGACCG
GATTCTTGTGTACCCTTAGCTTCCAGTTTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013216.1\|WP_021143829.1\|1522959_1525365_-\|glycogen/starch/alpha-glucan-phosphorylase	unknown	unknown	gnl\|CDD\|340853
NZ_CP013216.1\|WP_021143848.1\|1474261_1475800_-\|accessory-Sec-system-protein-Asp2	unknown	unknown	gnl\|CDD\|274739
NZ_CP013216.1\|WP_021147312.1\|1471444_1473820_-\|accessory-Sec-system-translocase-SecA2	unknown	unknown	gnl\|CDD\|236408
NZ_CP013216.1\|WP_021143832.1\|1519973_1520570_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013216.1\|WP_021143830.1\|1522187_1522748_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP013216.1\|WP_042762414.1\|1517647_1519912_+\|bifunctional-glutamate--cysteine-ligase-GshA/glutathione-synthetase-GshB	unknown	unknown	gnl\|CDD\|179427
NZ_CP013216.1\|WP_021143849.1\|1473812_1474259_-\|accessory-Sec-system-protein-Asp3	unknown	unknown	gnl\|CDD\|163423
NZ_CP013216.1\|WP_059749231.1\|1496541_1509507_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|375475
NZ_CP013216.1\|WP_021152305.1\|1469923_1471432_-\|accessory-Sec-system-glycosyltransferase-GtfA	unknown	unknown	gnl\|CDD\|131964
NZ_CP013216.1\|WP_021143836.1\|1513180_1515049_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP013216.1\|WP_021143846.1\|1477458_1478685_-\|accessory-Sec-system-protein-translocase-subunit-SecY2	unknown	unknown	gnl\|CDD\|237095
NZ_CP013216.1\|WP_101799703.1\|1510035_1511307_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013216.1\|WP_021143843.1\|1484433_1485642_-\|exonuclease-SbcCD-subunit-D	unknown	unknown	gnl\|CDD\|223497
NZ_CP013216.1\|WP_021143837.1\|1511561_1513085_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP013216.1\|WP_021143844.1\|1481257_1484437_-\|SMC-family-ATPase	unknown	unknown	gnl\|CDD\|223496
NZ_CP013216.1\|WP_021143842.1\|1485825_1489470_-\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	unknown	unknown	gnl\|CDD\|375450
NZ_CP013216.1\|WP_021143847.1\|1475786_1477358_-\|accessory-Sec-system-protein-Asp1	unknown	unknown	gnl\|CDD\|293598
NZ_CP013216.1\|WP_021143845.1\|1478779_1480873_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133037
NZ_CP013216.1\|WP_021143831.1\|1520550_1522080_-\|DUF1310-family-protein	unknown	unknown	gnl\|CDD\|337977
NZ_CP013216.1\|WP_021143835.1\|1515038_1516784_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055

Protein	Function_ID	Function_description	E-value
NZ_CP013216.1\|WP_021143829.1\|1522959_1525365_-\|glycogen/starch/alpha-glucan-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
NZ_CP013216.1\|WP_021143848.1\|1474261_1475800_-\|accessory-Sec-system-protein-Asp2	gnl\|CDD\|274739	TIGR03712, acc_sec_asp2, accessory Sec system protein Asp2. This protein is designated Asp2 because, along with SecY2, SecA2, and other proteins it is part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_CP013216.1\|WP_021147312.1\|1471444_1473820_-\|accessory-Sec-system-translocase-SecA2	gnl\|CDD\|236408	PRK09200, PRK09200, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP013216.1\|WP_021143830.1\|1522187_1522748_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.96525e-08
NZ_CP013216.1\|WP_042762414.1\|1517647_1519912_+\|bifunctional-glutamate--cysteine-ligase-GshA/glutathione-synthetase-GshB	gnl\|CDD\|179427	PRK02471, PRK02471, bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB.	0
NZ_CP013216.1\|WP_021143849.1\|1473812_1474259_-\|accessory-Sec-system-protein-Asp3	gnl\|CDD\|163423	TIGR03711, acc_sec_asp3, accessory Sec system protein Asp3. This protein is designated Asp3 because, along with SecY2, SecA2, and other proteins it is part of the accessory Sec system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	3.90043e-49
NZ_CP013216.1\|WP_059749231.1\|1496541_1509507_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|375475	pfam17998, AgI_II_C2, Cell surface antigen I/II C2 terminal domain. This is the second domain (C2) located in the C-terminal region found in antigen I/II type adhesin protein AspA from S. pyogenes. Together with C3, these two domains form an elongated structure, each domain adopts the DEv-IgG fold. Similar to the classical IgG folds, it is comprised of two major antiparallel beta-sheets, designated ABED and CFG. For the C2-domain, there are two additional strands on the CFG sheet. Furthermore, sheets ABED and CFG are interconnected by several cross-connecting loops and one alpha-helix (DH1). The side chains of D982 and N996 in the C2-domain are involved in hydrogen bonding with the side chains of R1264 and N1295 in the C3 domain. Main chain hydrogen bonding can also be observed between S992 in C2 and N1189/G1191 in C3, furthermore stabilizing the interaction between the domains. The C2 domain contains one bound metal ion, modeled as Ca2+, and both the C2- and C3-domains are stabilized by conserved isopeptide bonds, which connect the beta-sheets of the central DEv-IgG motifs.Other members of this family include Major cell-surface adhesin PAc from Streptococcus mutans and SspB from Streptococcus gordonii.	2.61092e-36
NZ_CP013216.1\|WP_021152305.1\|1469923_1471432_-\|accessory-Sec-system-glycosyltransferase-GtfA	gnl\|CDD\|131964	TIGR02918, lipopolysaccharide_biosynthesis_protein, accessory Sec system glycosylation protein GtfA. Members of this protein family are found only in Gram-positive bacteria of the Firmicutes lineage, including several species of Staphylococcus, Streptococcus, and Lactobacillus. Members are associated with glycosylation of serine-rich glycoproteins exported by the accessory Sec system. [Protein fate, Protein modification and repair].	0
NZ_CP013216.1\|WP_021143836.1\|1513180_1515049_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.38084e-169
NZ_CP013216.1\|WP_021143846.1\|1477458_1478685_-\|accessory-Sec-system-protein-translocase-subunit-SecY2	gnl\|CDD\|237095	PRK12417, secY, preprotein translocase subunit SecY; Reviewed.	1.82672e-140
NZ_CP013216.1\|WP_021143843.1\|1484433_1485642_-\|exonuclease-SbcCD-subunit-D	gnl\|CDD\|223497	COG0420, SbcD, DNA repair exonuclease [DNA replication, recombination, and repair].	1.91556e-52
NZ_CP013216.1\|WP_021143837.1\|1511561_1513085_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	6.23586e-93
NZ_CP013216.1\|WP_021143844.1\|1481257_1484437_-\|SMC-family-ATPase	gnl\|CDD\|223496	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair].	6.32561e-63
NZ_CP013216.1\|WP_021143842.1\|1485825_1489470_-\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	gnl\|CDD\|375450	pfam17965, MucBP_2, Mucin binding domain. This domain is found in bacterial cell surface proteins that interact with mucins. The archetypal member of this family is the Mub-R5 B1 domain. This domain has a beta-grasp fold.	1.99497e-18
NZ_CP013216.1\|WP_021143847.1\|1475786_1477358_-\|accessory-Sec-system-protein-Asp1	gnl\|CDD\|293598	pfam16993, Asp1, Accessory Sec system protein Asp1. Asp1, along with SecY2, SecA2, and other proteins forms part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. Asp1 is predicted to be cytosolic.	1.42331e-174
NZ_CP013216.1\|WP_021143845.1\|1478779_1480873_-\|glycosyltransferase	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	2.46929e-58
NZ_CP013216.1\|WP_021143831.1\|1520550_1522080_-\|DUF1310-family-protein	gnl\|CDD\|337977	pfam11311, DUF3114, Protein of unknown function (DUF3114). Some members in this family of proteins with unknown function are annotated as cytosolic proteins. This cannot be confirmed.	2.50972e-14
NZ_CP013216.1\|WP_021143835.1\|1515038_1516784_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.14238e-162

>NZ_CP013216.1|WP_021143842.1|1485825_1489470_-|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein
MRDMFNKRQRFSLRKYSFGVASVLLGVSIFSNAQGAQADETVAPTTAGMETTAEPDVVVEQSTPTTASVAPATTENAPSSVSTVALASEQPQSAAQESQATSTTSQTAASSEAASQAASQASSESVAATASSVATSAQSLSSTAVAEAPVAGQVSAQTSAAASVATAAETASAESTTNAVNSVLKVATSELAVTSSELTAAEASLNSENLINAMGLAVSNRSLRTADAVAVLTNAGASSTNPDLTNLGYKLAYLPERQQYFVNIDYINHLKVGRDNRGVMRPYDYITNGSYMVVVNYANLGIIDYVDEAGNKIPGSSTYRINNSTETITANGKTYNKIYDAGVTELPPVPAGYRIKYASADKSKANAYVDVLKSERQYDYNNGIATIRSERAWDRNQSRVVDLVQFANGSQGLDASIDANGGGQYLAPGYRYHIIVEKDTKDVTKATSQTVTYTGADTKTPAANTQNDFSFNGKEDPTTNTTTWTETTHTYGTVKTPVVTGYYADKAVAGGKTVTPDAPNVTDTVTYKAFGKFIAVDENGNPIPGVSTTAYTNDPNDATKMIAIDKTLPSIPGYTVKVIPASPSNPGEDTRVVYVAIVNDVTKATKQTVTFQGAGDKTPAADVKSDYTFAGKDNQATGKVTWNETSHTYGTVKVPVVNGYFADKAVAGGKTVTTDAPEATDTVTYKAFGKFVIVDENGNPIAGVSDTAYINDPNDPTKMIAVDKNLPTIPGYTAKVVPATPGDLSSDTKVVYVKNDQKASVVYRDETSGSTLETVALAGKSGEAVNYSTAERIKHYQDLGYVLVTDGYPAGASFDLDSTVDQAWTVSFKRVALDFNPDNAHEPGTPIYPNQPNGPKWPAKDAYLKDVTYTVHYASKDSDAKLPADSVQKAQWKRSLTLDSVTGDILTTGEWKADKTKFDLVITPMVNGYFADKGRVASQDVTMDSKVETVTYTKFGKIIAVDEKGNPIPGVEAVTYTNDPNDPTKAAMTLVPEVKGYKADKTGVTPSNPGEDTKVVYKVVNAEPAKPTVNKEVGTIVVIYRDEYGNQIKMPLVITNSVGSEVNVHGDRYIYRNGVKYELIRQEGKSTDKMTEGQTVVTYIYRKVEDGSTPSNGNGGQSGSSTSKAVKATSNGSKGSKGSGSGSAADGASDGKGSDKKKSGNKDGKKADGSDKAKEGDEQLPVTGESDNNLAAMGVVVMGLMSGLAAMNRRKNQD
>NZ_CP013216.1|WP_021143843.1|1484433_1485642_-|exonuclease-SbcCD-subunit-D
MKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEKVDGVIIAGDLYDRAVPPVDAIKLFNKTLARLVLEEQIPVYAISGNHDGAERLHFGRDFFQHQGLHLSTRLEEAFEPIELEACQIFLLPFIDPIDARIYYKDDENKEIQGIGDALAYILEDMEKAFDPDKAHVLVAHFAVSKKDDSDGQSLRELMLSETSNTVGGLTNVTSDLFKAFDYVALGHIHTRFASPSQRVQYSGSPVTFNVKEAKRREEKGVYILDLDATGDLSQTFHPLEVKRPILALQEPFETLMSPEFYKEQPCQKAWFAFDIQLFSRKELEGINVRARLEEIYGTDIVEITFSRLGDVREESLTVDQHLKDLEMQSPQEIVSDFYQTVTGGDVLSERQTALVESIFEEIGRSRQ
>NZ_CP013216.1|WP_021143844.1|1481257_1484437_-|SMC-family-ATPase
MRPVQLELTNFGPYRKEVINFTQFDHAPLFLIGGDTGAGKSTLFDAMTVALFATTSGDRNVEEMRSTFASPEDDLTKVTFYFQQGKHLYRIERVLQQERAKRGGGTTMQKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFSRFLKEDSKTKTQILKKIFGTGIFDRFQKSLEERLRQSNKDMDKRQAQLDGHFASQVWSEEELAVLTQTPASEKLARLEELLVQRQDNLEEQKSILKDAHEDLAKLQKSLQTAQDLAKIFQELKQAKERYCLEIEEGAQEQAEAKAHLDELQFAQGLQETISSLKQYQKQLLQLEQDLEIAQEELSEKQQAFEGVKAQKEALAAQSKDSLQKEEELETWKEDIIYAQSLVREQEKIKRSRTNYKQLEETYQQASKKIELLNQSLSELEANRLSVDSLHEAEKLLQSVGYSVDKQLAQDLKEIEGLNQELAKTEKRQQGLSLDIDQAQESLKELEDQLATTLASRRQLMIAQLQAELEDGQPCMVCGSFDHPKVDGTQADEAALKELMDQVEALQAQKERQVATLSNRQATLSEVESKRQDLLDQVAKVKLTLEKHYLELQEQVKGQFDFDFAEDYEADCGQTLLRKVEQYYQELHKRFDKEEADCLHYQDELAKVQEKSIDLAKAYQEAKAALDQAKERLKELQEAHQELESVEVYQERISLAKQELDLYNKQVKENSEAYNQLHADIQGIRGQLESLTKSKENASQETKRLSAELNQSLMAEGALTNDLEQIQLWLLEVNKQAIPELQAQLTSYQTLKQELQAQIVKGQELIEDQEKPDLGNLTQAVEDCQESYDKQLAQVSVMEQGLKDATATYQAAKTLQDSNQEAFKAHQELSDLVKVVKGENTALTGRLNLEVYVIRQYFQQILDYANANYIGLLMDNRYSFVLSEEGRRARDHFGLDINVYDQLTGSERSVKSLSGGETFIAALAIALSLSEVVQNTSKGAVVEALFIDEGFGSLDKEALTKAIAVLEQIGENRVVGVISHVDDMKEGIAQQLAIIKSHDGSSSIKIVDKG
>NZ_CP013216.1|WP_021143845.1|1478779_1480873_-|glycosyltransferase
MTEKISVIIPVYNVENQLQTCLDSVLGQTYQNLEIILINYGSIDNSDAICRSYAARDSRILYFKKDNGGLSDARHIGIRQAKGAYVTYVDAEDWVESTYLEELYKTLQAHKADIAVANYSVYKESEDLFYFYIKDEDYYEQVYSPAQIIDGLFEETNNINIALISATGKLYKRSLFNDLLFPKEHAGEDGFFNLKAYLMSERTVYLNKGLYVYRESPEMPSATWMQDWMMTLVYAMEERLAIVASHGFPLEKYMVTYRQMLEACLKNVEEQGLTDSDAYRSIQEKFQVLSLAPQRYETKKRAIVLAANYTYVDQVLTTIKSIVFHHRNIRFYLINDDFSQEWFRGLNRHLAAFGSEVINCRVDSSHIKQYKTNSNYASYLRYFVADFVSEERALYLDSDMVVTGSLEDLFTLDLQGRPLAAVRDYAIQVQDRQAMFDAGFMVIDTAYWKQYNMRRHFIDMTSEWHDKVPFAEQSILNMVFRNNWLPLSFDNNYAVTKSSLAGFHLPNGQDYPKVVHYASHRKPWLPLACQAYREVWWFYAQMDWSGVAENAALLPLSEDMIYPKGRPFTCLVYTNISEIPHLTDLISALPKVQFKIASRQHVADKLAQLITYPNVTVYSAIAGLNGLDLELLRTSDLLLDINPGRKVVEILDAFRFENKPILGFEDLKSTKHNQQTYSRDRWKEMAETIRQMRKKSL
>NZ_CP013216.1|WP_021143846.1|1477458_1478685_-|accessory-Sec-system-protein-translocase-subunit-SecY2
MKKISQSIITKRVLWTLFFLFIYCLGNQLVLPFVDLKNANIFGGAIGSLAFSSAMMGGNLRSMSLFSVGLSPWMSAMILWQMFSFSKKMGLKNLPIEIQDRRRMYLALGIAIVQSLAVSLNLPIVSGVNASLAIFMNTILLIAGTFFLVWLSDLNSLFGIGGSIVILMASMMANLPYQIMDSIEKLGIGWDVLLPLILFSLVFLYISGVVQRARYRISINKINIHNRFKQYSYLDIMLNPAGGMPFMYAMSLVSIPQYVFMLIQFIHPENKWTSGAIKALTVGQPLWLVVYLVMLFVLGLAFAFVNVSGEQISERMRKSGEYIYGVYPGQETSAYINHLVLRLGFIGALYMLFMAGAPMLIILVNPDYLQLSMIPGTFLIFSGMIYNVNEEMKALKLNTSYTPLFENV
>NZ_CP013216.1|WP_021143847.1|1475786_1477358_-|accessory-Sec-system-protein-Asp1
MYYFIPAWYGQTDEFWKTVIDPWYRIRQKIEFDDSLHQVRIFQDEDLAPQLLLLAYQPHLRYFLHRHDVLEVGYTAIFDLIQGITDEDMKNLQVTDLEWPEGATFVHTPFAIVVQCQHKRYAEIEFGSEGFIGMIRYYKDEQIIREDIYDDRGFISSSLYYEGGQPSYRNYLNAKGVWQLCHFFDGRGIVANPRTEGRFNKSYYSNLSEVIWEFLTKFLDEKVEAEDRFVIASDLRHNKHLFEHLPADNTKILTWFAERNQDDSIDTYEVFLPQVDLLIADRYDYLEQLQVAYPEEAKKLKHMASFDTRLALGTSQRVKESKIFYQVDFDQLDLEAIYQVLAFVAKYPKTQVEFGAFNANPEQLGSLQNQVEKMIEERLSPDAFEEVVESSGAENKLEENNEIVSRFSFQDLRDETALIKALQFTRLIVDLSKEPNRYTQIAGISAGIPQINRVASEYVTHQENGYILKHLSDFEKGAYYYLGQLNNWNRSLIYSIEKIKENTGDRLVQKWENWLKEEQNDQG
>NZ_CP013216.1|WP_021143848.1|1474261_1475800_-|accessory-Sec-system-protein-Asp2
MTKDNRLKILQVGSSNWSENQEIPENMKWYYCNLGQLETLQETIEEDEIKTFTAVIVDSLAGLEELMTIKEHLIPHTIFFDQTIEVPDESLLQFLKEVCAVPTDFSNQGQLLFTLSKALFSGQYGDKMFPFTTQVNPNFTGQVTYHGYENVILKGEYGQDFSPVLDWTYNVRASKENPIELWLEFEKEETCECRLILNLLPEGSVAGIFKTYIVSEEEMRKGAIVLDEDTTFLLSASLEMKGQGQITIGGLHQRLTRFQFGKFVLGGGILHDSKRQEINYFFYPGDFKPPLSVYFSGFRPAEGFEGFGMMKGMGTPFLLFSDPRLQGGAFYMGTEELENSIKDTIQHYLDYLGFDNSQLILSGMSMGTFPSMYYGADFEPHAIIMSKPLANVGTIGNRARLLAPEVFPTGIDVLHLQTGRLDNEGVEALNQKFWDKFEKADFSDTTFGLSYMKDEDMDPTAYEDITKSLYYSGAKILSKGTSGRHNDDSYTATTWFVNFYRMILENDFGRKE
>NZ_CP013216.1|WP_021143849.1|1473812_1474259_-|accessory-Sec-system-protein-Asp3
MFRNKKSEILWGLNHKAYMYGSKIVKRQDGSVQFYNPLVPSGTEIQSWVAIQNYQAGRTQPALPLLKKGHSYDLTANLEAVPTGSVFLKVSFLDRYGNEIKQLIEKSTHMTFIYPHEAYTYRISLLSAGVKELDFYSLKLEETGEEHV
>NZ_CP013216.1|WP_021147312.1|1471444_1473820_-|accessory-Sec-system-translocase-SecA2
MFKQLNPILPVKEILKEINGLADEIAGLSNLELKNKTQEFKERLAQGESLDDLLPEAFAVVREADKRVLGMFPYDVQVMGGIVMHQGHIAEMNTGEGKTLTATMPVYLNALSGEGAILVTTNEYLAIRDAEEMGQVYEFLGLTIGVPCVEGSNEMEPAEKRAIYQSDIVYTTNASLGFDYLIDNLASNQDGKYMRPFNYAIVDEVDSVLLDSAQTPLIISGAPRVQSNYYGMMDTLMTTLVEGEDYIFKEEKGEVWLTTKGAKAAENYLGIGNLYDEENSTFARHLLFSLRAHLLYKKDKDYIIRDGKKGPEVVLLDKSTGRLLELTKLQGGLHQAIEAKELVALSQETRAMASITYQSLFKKFKKISGMTGTGKVAEKEFLDTYGMKVIQIPTNRKKQRIDYPDKIYATLPEKVFASLEYVKHYHEKGNPILIFVGSVEMSELYSSLLLREGIAHNLLNANNAPREAEMIAESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLVVIGTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKYGPSWVHRTYKEYAISDHIEPKELTGRKYRKLVQKAQEASESSGRTSRRQTLEFAESMNIQREMIYAQRDRLIFHNQGLDTVIDEVLDDFIDQAVADEDFSKAENLYHFILRNISFRINEIPKDLDLNNREEVLELIYQFAYRELEAKKQELKTKELNEYFQRLAMLKAVDDNWVEQVDYLQQLQMAIGSQQLSQKNPIVEYYQEAYKGFEAMKRQIRKDMVRNLLLSQVQVTKKGDIISHFP
>NZ_CP013216.1|WP_021152305.1|1469923_1471432_-|accessory-Sec-system-glycosyltransferase-GtfA
MTVYNINLGIGWASSGVEYAQAYRAKIFQEMGQEAKFVFMDLILGDNIEHMTSKIGFSDDQIIWLYNYFTDVKIAPSTIKLAEIEAILPANPKRKEVSGSVIRYHYPQDDLVVACHLRATDGVSVETVSYFVNDKLLRKDFYSYTRYCSEYYAPKDNQAKVYQRRFYNEDGSNAYDMIVGDNNQDIYRFPDQVLYGKQEFLRYFFKRLALTKDDVVILDRETGIGQLVFEEAQAARLGVVVHAEHFSVNQTDDDYILWNNYYEYQFTNADKVDFFIVATDRQKEILERQFRHYTNHDPKIYTIPVGSLPELVGQDKARKPFSMITASRLAQEKHIDWLVRAVIEVHKTLPDITFDIYGSGGMDAKLREIIAEGQAGDYIRLMGHADLTDIYSQYEVYLTASTSEGFGLTLMEAVGSGLPMIGFDVPYGNQTFIEDGSNGYLLPVAENHVVDVITKSYKDAIVRLYEEGNIEAMRQKSYDLAQGFLTSQVKAAWKQLLEEVRS
>NZ_CP013216.1|WP_059749231.1|1496541_1509507_-|YSIRK-type-signal-peptide-containing-protein
MKDIFNRRQRFSLRKYSFGVASVLLGTALFAAHTAQADEVTAPDASSSNPGSSVEGESSSDLVETSTASTAQADPTAAVSSTDATASTFNLTPEASTDKAAAETTEKTATETAKPEAAKPASETAKPTEKATSEAAKPAAAASTNAASNNVETTASATTAAATPAATAANRPSATAAPVAEETAAAETAAAATSVKPNVTARAYSVRAAAEDRSAVLDRAATDMTNGGALAMSRSRRNRRAATDHNNEPVAVATFLKDGEVATPDMTDPNGASVASQTVPAGYQAKEGDFYTYAIWDLTEFNKRYNTKYYARAYKRFDDSTDTTVELLDKNTGSVVETRTVTASSGVQKFTTTTAASNSQLTFQVDYKAGTAPSGKKAEPFIQNGYEVGKSITDLVAAGHKLTEAERALYTAVYNARTTTDIINVVEPAYNGRTITDSNAKIPVTINKTTYYKVVDKNNPTFNANKTDKTVQDYKENGNEVELARYTLKAEEGQRFTASGERQFDGYKLYQTADANDQSGTVSRPYTVGTKFMDADRYGIKRIKEVVGEDGSVVIRVYLLDPRQQSKRSDGSLSTDGYMLLAETKPIKPGEWNSQDLVVKKSPLYTIAHTVTDEKTGAKTNYPNGKEVPFDFQKASGYAPYHSVFVPFLGDGIGHGSANSQLERGVGGIGTNVDLLNTLTPYKQPIYYYVKQEPVTVTPEVEKQLEGRVLVDGEFSFKIKEVNENKSLPSYEETVTNKNGKATFSKLSFNKVGTYKYTISEIAGSDANVDYDAMTVTMTVTVTENSKGDLQASVKYSGTGGFASSADDKVFNNYVVAPVKTKFDFSKALAGRELKAGEFSFVLKDSTGKVLQTKTNTKAGVVAFDDLTFDNTQVGTHKYTVEEVIPAAKEAGMTYDTMKAEVTITVTKEGHVLKATNTLPTDTEFNNTFTPAATQAQFRFTKRLEGKTLEANAFTFELLENGNVIQTKQNAADGSIQFDPISYATVGTHTYTVREKAGTDTNIDYDSMNAVVTVNVTKDAQTGLLNAAVTMPADTEFNNFAVAPVKTKFDFSKALAGRELKAGEFSFVLKDSTGKVLQTKTNTKEGVVAFDDLTFDNTQVGTHKYTVEEVIPENKEAGMTYDTMKAEVTITVTKEGHVLKATNTLPSDTEFNNTFTPAATQAQFKFTKKLEGKELTKDAFTFELLENGKVIQTKKNAADGTIQFDAISYDKEGSHTYTVREVAGTDTNIDYDDMNAVVTVNVTKDAASGILTANVTMPEDTEFNNFAVAPVKTRFDFSKALAGRELKAGEFSFVLKDSTGKVLQTKTNTKEGVVAFDDLTFDNTQVGTHKYTVEEVQGSEAGMQYDTMKAEVTITVTKEGHVLKATNTLPADTEFNNTFTSAPTQAQFKFTKRLEGKVLEADAFTFELLENGNVIQTKKNAADGSITFDAIEYSAEGEHTYTVREKAGNDTNIDYDTMNAVVKVKVTKDAATGLLSTAVTMPEDTEFNNYVVAPVVTKFDFTKKLAGRELKAGEFSFVLKDSTGAVVETVKNDAAGNVTFSELSFDNTKVGTHTYTVEEVIPENKEFGMTYDQMKATVTVEVAKNGHTLTTVTNVTSTGGVDANGNATDGTADKEFNNKVTPPNTPEFQPEKFVVSKEKYDITGDKLMDDDDDVPGNEYTATNANPYVDGVANNEPENLNTKTVERGSKLVYQVWLDTTKFTEANNIQYVGVSDKYDAEKLDVNAADIKAYDSVTGADVTAKFDIKVENGTITATSKDEFIKDKVNNPVIDTTKFAFGRYYKFDIPATVKESVKAGADIENTANQTVHVYNPVSKTVEKPEKPTQKRVNSVPVPVEMNFTKRLEGRELQANEFEFVLKKDGVEVERVKNDAAGKIVFETLKFGRDDLGKTYNYTVEETPGTDTTVKYDTMVATVKVVVSHDGTAKAIVANVTDAADKEFNNRVTPPEEPKFQPEKYVVSKAKFDITGTKLVDDDSELTDKYGETNTNPYVDNTNNNEEENLNTKSVERGSKLYYQVWLDTTKFDAANKDNIQTVGITDNYDKDKLTVNASEIKVYDSVTGADVTNKFDIADNNGVLTANLKAGFTKSLGDAENTQIIDTTKFEFGRYYKFDIPATVKDDVVAGADIENKAAQVVNYYNPVSKTVEKPNKPTEKRVNSVPISVEFNFTKKLEGRDLKAGEFTFELKDSDNVVIATATNDAAGKIKFSPVEYTNKAGETVTALKYKKGQEGTYKYTVTEVKGTDATVTYDEMAAVVTVTVSHDGTAKALITNVTDPADKEFNNRVTPPEEPKFQPEKYVVSEEKFDITGDKLVDDDKELADKYADTNANPYADDASNNEKQNLNTKTVKRGDKLVYQVWLDTTKFDANNKDNIQSVGISDDYDEAKLDLDATKIKAYDSVTGDDVTAKFDITVNNGVITATLKDGFTKSLGDAENTQVIDTTKFAFGRYYKFDIPTTVKADVKGGVDIENTAAQVVNYYNPTTKKVEKPSKPTEKRVNNVPVEVEFNFTKRLEGRELKANEFSFVLKDSEGKTLETVSNDASGNVKFSAMSFKKGQEGVHNYTVEEVKGSDATVTYDTMKANVTVTVKHDGTAKVLIATVGDIADKEFNNRVTPPDEPKFQPEKYVLSDGNGKFDITGTKLLDDDKELADKYAETNANPYADKADNNEAENINTKAVKRGDTINYQVWLDTNQFDANNKDNIQTVGITDDYDEAKLEVKQSDIKAYDGKTGADVTDKFDISIANGVITANLKAGFTKSLGDAENTQIIDTTKFEFGRYYKFVIPAKVTDGAYDGAEIENTAAQVVNYYNPTTKTVEKPNKPTEKRVNNVPTAIELIFGKTLNGRKLQDKEFTFELKDEKGNVLETVKNDAEGKVKFSTINYAKADLGKTFNYTVEEVKGTDTTVTYDNMKVNVTVQVIQPSVGDQLSTVISYATVGGDAYGGDDRVFDNNVTPNFKPEKYVVSEPSFDIIGNKLADDDDSADKVEIQNLNGKTLKRGQKIYYQVWLDTRDFTAESNLQTVGITDNYEEAKLDIDASEIKVYDGITGKDVTDKFDIKVENGVLYGTSKASLTKAISATDATPVIDTTKFEFGRYYKFDIPAVVKDIDANDGVDIENTANQTIHQYNPFNKKVTTPEKPTQTRENNVPVPLEFNFTKRLEGRELTAGEFSFVLKDKDNKVLQTVTNDKDGHIKFEKLLFSKADLGKTFTYTVEEVAGKDTSITYDAMKATVTVEVTKEGKVLTTVVNHASAGGFASSANDKEFNNKVRPPETPKFQPEKYVVSEAKFDITGTKLVDDDKELANKVADTNANPYADDASNNELENMNTKSVKRGDKLVYQVWLDTTKFDANNKDYIQTVGISDDYDETKLELDATKIKAYDSVTGEDVTAKFDITVENGVITANLKDGFTKSLGDAANTQIIDTTKFAFGRYYKFDIPTTVKDTVPGGVDIENTAGQVVHYYNPTTKKVETPKVPTEKRVNSVPVEVGFNFTKRLEGRELKANEFTFELKDAAGKVVETVKNDAAGNVKFSKLEFKKGQEGVHKYTVEEVKGTDATVTYDTMKANVTITVSHDGTAKALVATVGEIADKEFNNTVRPPEKPKFQPEKYVVSEAKFDVTGTKLVDDDKELANKVADTNTNPYADDASNNELENLNTKSVKPGQKLYYQVWLDTTQFDANNKDHIQTVGITDDYDETKLDVDASAIKAYDSVSGADVTSKFDIKVENGVVTANLKDGFTKSLGDAENTQVIDTTKFEFGRYYKFDIPATVKADVAGGVDIENTAAQVVNYYNPTTKKVEKPNVPTEKRVNSVPISVEFNFTKRLEGRELKANEFSFVLKDSEGKTLETVSNDAKGNVKFSPIEYKKGQEGTYKYTVEEVKGTDGTVQYDGMKALVTVEVSHDGKAKALITKVTDPADKEFNNTVRPPEKPKFQPEKYVVSKEKFDITGMKLVDDDAELKDKVGDTNKDPYADSTANNEAENINTKTLKKGDKFVYQVWLDTTNFTDAHNIQSVGVTDKYDSENLNINVADIKAYDSVTGEDVTAKFDIKVENGVITATSKSDLTKSLGDAENTQVIDTAKLAFGRYYKFDIPATIKGTAKDGVDIENTASQIVHQYDPTKKSVEKPEKPTEKRVVNIPTKVEFEFTKKLEGRELKAGEFSFVLKDSKGNVIETVSNDANGKIKFSALEYKRGEEGTHVYTVEEVQGNDATVTYDKMVATVVVSVTKDGKVLTVTSQLPEDTEFNNIVTPPTPPTPPTPPTPPTPPTPPTPPTPPTPVVPPVTPPTTPEAPKGPALPETGDDASMAAMALGGILAAAGLGLAGKRKKED
>NZ_CP013216.1|WP_101799703.1|1510035_1511307_-|hypothetical-protein
MNRLSCSCLHLPPNVTCLDCTLSERFCQMKIKNPTLLDRRCTLSIVSTYAILKAILKMEIVMENKFVKKPTPKGDKSTRIVFIGLLVALLFIIAGTAIFFAVNSSSKATKGLAASSKSSTTVYSGSNAEDPLFKITLKTFGDNKEFLLVTPNPGHDRNMFNIVGVAGQYLVTQEYKGGESGKKNAKGETLYKYDYFNIYMYDTEKPNQKPKQIDLLKLAKKAGDEDYLNQASLRLFMLNEQAYLQMPFGASSADFASNKKYLNLKTQKIEEMNIPANSNTLDSELDYANVDMRKTLEPFGLEMWPDATNGKDLDYPRETPIASLPALYYISEKDRSLNMDSTNFAKEHKDAYESIKTKHARIYTIPSKVNNETWFNTLLHWVAPEGQDAYELPVRAFRPTQEEGKVKSYQELQTWNDNHIRKK
>NZ_CP013216.1|WP_021143837.1|1511561_1513085_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MIQIQHLTITHTKDLRELVHDLNLTIATGEKVAIIGEEGNGKSSLLALLVNPKAHFDHLSYEGTINKPDSPQVYIPQQISDDLQSLTLNDYFFADTYDLDYATLYRLADELHFDSERFASSQLVSSLSGGEKLKIQLIRELARPHDIIFLDEPSNDMDLTTMTWLKNFIKHSDQTIIYISHDEDLLSQTADTIIHLELLKRRRQARTSVEHLDYDNYSQQRTDAFQQQMQQAKTEKKAYDKAMAKHRRIKQNVQTTLRNTHDSTQGRLVAKKMKAVLSQEKRYDRLAQDMTQIPDKEDSIELFFSHITPLPQGKYLLNLDKKQINIAPHLTIDHLKLSLKGQEKIGIVGDNGCGKSTLLHFLYQELSKKTDLTIGYMPQHYDTILQNDLSPIAFLSKTGDKTEREIISSHLANLNFSHDEMNHAIDDLSGGQKGKLLLLHLVLESPQLLILDEPTRNFSPTSQPQVRQLFENYPGAILTVSHDVNYLRQVCQKIYRLDSHGLKEVEI
>NZ_CP013216.1|WP_021143836.1|1513180_1515049_-|ABC-transporter-ATP-binding-protein
MQNKKKANWGSLARLLRFLWQDYKLSLSIAFVLIVVASLATVNLTASIQSLVDVYVQPLLKSGSHDFGPLLRFLTSVAVFCLIGVIANYVSSLLMATISQDSLRSLRNQLFARMQKLPVRYFDTHQHGDIMSIYTNDIDALRQAVEQSIPQLLQTTITIIGVTVTMLTVSPLLFIVVLIMVGIMFMVIKNVSAKSGRYFGEQQKNLGIENGFIEEMMSGQKVVKAFVHEEESMADFDKINKQLFESSYLANRYANVLMPILGNLGNVSFVLTALVGGLFALNGVGGLTIGGLMAFLQLNRSFNGPITQVSQQLNFVLMALAGADRIFDLLDEAEEVDQGKVTLVNYELVDGQMVATDKKTNHWAWKHPRPNGDYELVELVGNVVFQDVDFSYDGKKQILHDVNLYADKGQKVAFVGATGAGKTTITNLINRFYDIQSGVITYDGIDVKLIEKNSLRRSLGIVLQDTHLFTGTIAENIAYGRADATREEILEAARIANVDSFVQHLDNGYDTVLTDDGAGLSNGQRQLIAIARAALANAPVLILDEATSSIDSRTEKMVQEGMDRLMEGRTVFVIAHRLSTIVNSDVIMVMDHGRIIERGDHDSLMEQGGTYYRLYTGGLEID
>NZ_CP013216.1|WP_021143835.1|1515038_1516784_-|ABC-transporter-ATP-binding-protein
MFQTLIPQIKEYKKPSILASLFMTLEVMFEISIPFVMANLLDKGVQQSNMSNIWLYGGLMLVCAFLSLFCGMQSARYAAFASAGFAKNLRQAIFKKVQTFSFENIDKFSAGGLVTRMMTDVTNVQNSYQMIIRVCVRAPLNLIFAIAASFLINAEMAWIFVGVTIFLGVVLAIITKIVYPLFTQVFEAYDNLNNSIKENITNMRVVKSYVKEQEETDKFKKASRRIYKMFMRAIRVVIMSNPAMMLSMYASFLMISWFGAHLIVGGSLTTGELTSMFSYTMTILMSLMMFMMIFVMLSISTASVERIDEVLSTEATIVSPENGLTEVSDGSISFDHVDFSYTDENGDKTHVLKDITLDIKSGEVIGILGGTGSGKSSLVQLIPRLYDVEEGQVRVAGHDVKDYDLDSLRKQVAMVLQTNVLFSGTIKENMRWGNKQATDEEIIEACKIAQADEFIQEFKDGYDTKIERGGANVSGGQRQRLCIARALLMNPKILILDDSTSAVDTKTDSLIRRGFASSLKETTKIIIGQRISSIQDADRIIVMNDGRIDAIGTHDDLIANNAIYREVYKMQTQGKGVADAE
>NZ_CP013216.1|WP_042762414.1|1517647_1519912_+|bifunctional-glutamate--cysteine-ligase-GshA/glutathione-synthetase-GshB
MTINQLLQKLEPTSPILQANFGIERESLRVDRQGKLAHTPHPSCLGARSFHPYIQTDFCEFQMELITPVAKSTTEARRFLGAITDVAGRSISKDELLWPLSMPPRINAQEIQVAQLENEFERHYRNYLAEKYGTKLQAISGIHYNMELGKDLVEALFQESDQIDIIAFKNALYLKLAQNYLRYRWVITYLFGAAPVAEQGFFDQEVPEPVRSFRNSDHGYVNKEKIQVSFASLEDYVSVIENYIEQGDLIAEKEFYSAVRFRGQKVNRSFLDKGITYLEFRNFDLNPFERIGISQNTMDTVHLLLLAFLWLDAPENVDQALAQGHALNEKIALSHPLEPLPSEAETQNIMTALDQLVQHFGLGDYHQSLVKQVKDAFADPSQTLAAQLLPHIKDKSLADFALDKALAYHDYDWTAHYALKGYEEMELSTQMLLFDAIQKGLHFEILDEQDQFLKLWHQDHVEYVKNGNMTSKDNYVVPLAMANKTVTKKILSNAGFPVPAGDEFTSLEQGLAYYPLIKGKQIVVKPKSTNFGLGISIFQEPASLDNYKKALEIAFAEDTAVLVEEFIPGTEYRFFILDGRCEAVLLRVAANVVGDGKHTIRELVAQKNANPLRGRDHRSPLEIIELGDIEQLMLTQQGYAPDDILPEGKKVNLRRNSNISTGGDSIDVTETMDSSYQELAAAMATSMGAWACGVDLIIPDKTQPASKEKPHCTCIELNFNPSMYMHTYCAEGPGQAITPKILDKLFPEVATSQT
>NZ_CP013216.1|WP_021143832.1|1519973_1520570_-|hypothetical-protein
METKKTETLDSVLVAKNFYRVRDAYAIKLYGQDEGMSFDVAGQRLFGSNIAIKDGLLYGSSLGDLTIEAYFQGEASYLLEATQKLPVDKNRIKSNHYSQDIVLNKVWTSLENQEFSNSIITQFQDKTLLKLRISYNKDFLPTKIQGFYNSQTFNGWQDLFYIDYPYSDQEAFNQAQDAYIQHIQYMETHPEEEAGEFG
>NZ_CP013216.1|WP_021143831.1|1520550_1522080_-|DUF1310-family-protein
MKKVILQYLASALAVILILGLVVFNRQRNHSLVKKVKDPEISYIYKDSLENLDRLALSQAGIIQSYQLDSLSVRKEDGKIHLVLHINHSYDMQVNLVLKSDIYGDLSVVQATPSKALKLALEDESYQKRLTLISQKADAIISRDHWDQGIKPAYVAQVRSKMKKTSLNQLEKVLQEIDQESKEVGSDTYTSFFQASQLPNHDKLNLVMEHMQVYVDKYQFLQLGKSGYKFSKKLEPTSPFYSYFREAIMETYQTDLGLGVDELGIKLHLFRSWIDKQSMDYIKTNYKGKTDLDKLLAYSKDKKIKLDYTTGASYHNRSLGDFTYPENMKIQLPQTSVMGPYGVSNSRFIEFIVNMDTGKFVSEWNVYKKRKDGSIDSNPKHYKIEDGADIADTDSANYGLSKGLNADLPAYLNNSHTYLDVRHPADNAIRRKMVRKWKNAKNVLNGGRYADIVKKGGLKDLETWKQVKAEDRLQVYNAYLDYIRSHLVLNGFDSFYQETYNTQGGDKKD
>NZ_CP013216.1|WP_021143830.1|1522187_1522748_-|GNAT-family-N-acetyltransferase
MALRSQLITKEFPELDRVERLNNEAFPEEERIPLIDFLKLDGRDDYHFFAFYDEDDFVGFASVLYNAKVFYVSFFAIVPQMRSHGYGSEIIDKLVDFYGPSRSMVLEVERLDEPNDNPEQRVARWDFYKRNGFKTSNAFLEYEGLSFEILYRGNHFDEKAYRDIFHKLQENAYFDFSIKHRRLSDL
>NZ_CP013216.1|WP_021143829.1|1522959_1525365_-|glycogen/starch/alpha-glucan-phosphorylase
MQLENLTKEQFIRDFKDTLHQEQLIKVAKATPTEIFTALAGLIRKYYTNTWIERNHALSDNQEKIAYYFSIEFLPGRMLETNLLNLGILDLVKEGFAELDIDFREVVEAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVDGYQVELPDGWFGSTGNVWETRKDHDIVYVKLFGDVVLESNEDGRFVPTYKNAQVLRAVPYDVPQIGYQNGVINNLRLWDVEIPEEYELDYPTLEARRRVKDITAILYPDDSTIEGKELRLVQEYFMTSAGLQTIIKSYLKMGLPLKDIHEKVSVHINDTHPAVAPAEFMRLLLDEYGLSWEDAWNATVKTMSYTNHTILQEALEKWDQQLFKRVLPRVYQIILEIDNRYIAEMAGRGIAADVIERTRIVKDNQVHMANLAIIGGHSVNGVAKLHTELLKEDTLHDFYTIYPEKFNNKTNGIVQRRWTQIAAPELSAAIDDVIGDGWRNDIHELENLTTYLDDKEVLNQFYQVKKTAKQRLADYIKETTGVEVSTDAIFDVQVKRLHAYKRQLLNLLHIIKLYWDLKDNPDKDMVPRVFIFGAKAAPGYHFAKSVIKLINEVANLVNNDESLQGKLKVVFLENYRVSLAELIIPAADVSEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGDENVVIFGMDKDEVYEHYARHDYYSRAVYENNPVIRRVVDTFVNGTIPNAQSEGTEIYEALITHNDEYFLLEDFAAYVEAQEKIDALYRDHDKWARMSLANIAKSHKFTSDDTITEYAKEIWELKK

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Crispr_ID: NZ_CP013216_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013216_4

1496671-1496778

Orphan

Consensus_repeat	Method
TGGAGTTGGAGGAGTCGGTGGTGT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP013216_4

>merge|NZ_CP013216|4|1496671-1496778|CRISPRCasFinder
TGTAGTTGGTGGTGTCACTGGTGGAACCACTGGAGTTGGAGGAGTCGGTGGTGTTGGAGGAGTTGGTGGTGTTGGTGGAGTCGGTGGAGTCGGTGGTGTTGGAGGAGT

>NZ_CP013216|4|4|1496671-1496778|CRISPRCasFinder
TGTAGTTGGTGGTGTCACTGGTGG	AACCACTGGAGTTGG
AGGAGTCGGTGGTGTTGGAGGAGT	TGGTGGTGTTGGTGGAGTCGG
TGGAGTCGGTGGTGTTGGAGGAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013216.1\|WP_021143829.1\|1522959_1525365_-\|glycogen/starch/alpha-glucan-phosphorylase	unknown	unknown	gnl\|CDD\|340853
NZ_CP013216.1\|WP_021143848.1\|1474261_1475800_-\|accessory-Sec-system-protein-Asp2	unknown	unknown	gnl\|CDD\|274739
NZ_CP013216.1\|WP_021147312.1\|1471444_1473820_-\|accessory-Sec-system-translocase-SecA2	unknown	unknown	gnl\|CDD\|236408
NZ_CP013216.1\|WP_021143832.1\|1519973_1520570_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013216.1\|WP_021143830.1\|1522187_1522748_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP013216.1\|WP_042762414.1\|1517647_1519912_+\|bifunctional-glutamate--cysteine-ligase-GshA/glutathione-synthetase-GshB	unknown	unknown	gnl\|CDD\|179427
NZ_CP013216.1\|WP_021143828.1\|1525690_1527121_-\|glycogen-synthase-GlgA	unknown	unknown	gnl\|CDD\|234809
NZ_CP013216.1\|WP_021143849.1\|1473812_1474259_-\|accessory-Sec-system-protein-Asp3	unknown	unknown	gnl\|CDD\|163423
NZ_CP013216.1\|WP_021143843.1\|1484433_1485642_-\|exonuclease-SbcCD-subunit-D	unknown	unknown	gnl\|CDD\|223497
NZ_CP013216.1\|WP_021143836.1\|1513180_1515049_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP013216.1\|WP_021143846.1\|1477458_1478685_-\|accessory-Sec-system-protein-translocase-subunit-SecY2	unknown	unknown	gnl\|CDD\|237095
NZ_CP013216.1\|WP_021143841.1\|1489929_1496085_-\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	unknown	unknown	gnl\|CDD\|369436
NZ_CP013216.1\|WP_021143835.1\|1515038_1516784_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP013216.1\|WP_021143837.1\|1511561_1513085_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP013216.1\|WP_021143844.1\|1481257_1484437_-\|SMC-family-ATPase	unknown	unknown	gnl\|CDD\|223496
NZ_CP013216.1\|WP_021143842.1\|1485825_1489470_-\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	unknown	unknown	gnl\|CDD\|375450
NZ_CP013216.1\|WP_101799703.1\|1510035_1511307_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013216.1\|WP_021143845.1\|1478779_1480873_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133037
NZ_CP013216.1\|WP_021143831.1\|1520550_1522080_-\|DUF1310-family-protein	unknown	unknown	gnl\|CDD\|337977
NZ_CP013216.1\|WP_021143847.1\|1475786_1477358_-\|accessory-Sec-system-protein-Asp1	unknown	unknown	gnl\|CDD\|293598

Protein	Function_ID	Function_description	E-value
NZ_CP013216.1\|WP_021143829.1\|1522959_1525365_-\|glycogen/starch/alpha-glucan-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
NZ_CP013216.1\|WP_021143848.1\|1474261_1475800_-\|accessory-Sec-system-protein-Asp2	gnl\|CDD\|274739	TIGR03712, acc_sec_asp2, accessory Sec system protein Asp2. This protein is designated Asp2 because, along with SecY2, SecA2, and other proteins it is part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_CP013216.1\|WP_021147312.1\|1471444_1473820_-\|accessory-Sec-system-translocase-SecA2	gnl\|CDD\|236408	PRK09200, PRK09200, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP013216.1\|WP_021143830.1\|1522187_1522748_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.96525e-08
NZ_CP013216.1\|WP_021143828.1\|1525690_1527121_-\|glycogen-synthase-GlgA	gnl\|CDD\|234809	PRK00654, glgA, glycogen synthase GlgA.	0
NZ_CP013216.1\|WP_021143849.1\|1473812_1474259_-\|accessory-Sec-system-protein-Asp3	gnl\|CDD\|163423	TIGR03711, acc_sec_asp3, accessory Sec system protein Asp3. This protein is designated Asp3 because, along with SecY2, SecA2, and other proteins it is part of the accessory Sec system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	3.90043e-49
NZ_CP013216.1\|WP_021143843.1\|1484433_1485642_-\|exonuclease-SbcCD-subunit-D	gnl\|CDD\|223497	COG0420, SbcD, DNA repair exonuclease [DNA replication, recombination, and repair].	1.91556e-52
NZ_CP013216.1\|WP_021143836.1\|1513180_1515049_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.38084e-169
NZ_CP013216.1\|WP_021143846.1\|1477458_1478685_-\|accessory-Sec-system-protein-translocase-subunit-SecY2	gnl\|CDD\|237095	PRK12417, secY, preprotein translocase subunit SecY; Reviewed.	1.82672e-140
NZ_CP013216.1\|WP_021143841.1\|1489929_1496085_-\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	gnl\|CDD\|369436	pfam07580, Peptidase_M26_C, M26 IgA1-specific Metallo-endopeptidase C-terminal region. These peptidases, which cleave mammalian IgA, are found in Gram-positive bacteria. Often found associated with pfam00746, they may be attached to the cell wall.	0
NZ_CP013216.1\|WP_021143835.1\|1515038_1516784_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.14238e-162
NZ_CP013216.1\|WP_021143842.1\|1485825_1489470_-\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	gnl\|CDD\|375450	pfam17965, MucBP_2, Mucin binding domain. This domain is found in bacterial cell surface proteins that interact with mucins. The archetypal member of this family is the Mub-R5 B1 domain. This domain has a beta-grasp fold.	1.99497e-18
NZ_CP013216.1\|WP_021143844.1\|1481257_1484437_-\|SMC-family-ATPase	gnl\|CDD\|223496	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair].	6.32561e-63
NZ_CP013216.1\|WP_021143837.1\|1511561_1513085_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	6.23586e-93
NZ_CP013216.1\|WP_021143847.1\|1475786_1477358_-\|accessory-Sec-system-protein-Asp1	gnl\|CDD\|293598	pfam16993, Asp1, Accessory Sec system protein Asp1. Asp1, along with SecY2, SecA2, and other proteins forms part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. Asp1 is predicted to be cytosolic.	1.42331e-174
NZ_CP013216.1\|WP_021143845.1\|1478779_1480873_-\|glycosyltransferase	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	2.46929e-58
NZ_CP013216.1\|WP_021143831.1\|1520550_1522080_-\|DUF1310-family-protein	gnl\|CDD\|337977	pfam11311, DUF3114, Protein of unknown function (DUF3114). Some members in this family of proteins with unknown function are annotated as cytosolic proteins. This cannot be confirmed.	2.50972e-14
NZ_CP013216.1\|WP_042762414.1\|1517647_1519912_+\|bifunctional-glutamate--cysteine-ligase-GshA/glutathione-synthetase-GshB	gnl\|CDD\|179427	PRK02471, PRK02471, bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB.	0

>NZ_CP013216.1|WP_021143841.1|1489929_1496085_-|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein
MKQANHVFEKVTKYAIRKLSVGVGPVAIGTFLLAGGLFVSKPVSADQVTSDASVHMAYVTENELTAEEQKQVVHAIPKEYQNEDTFYLVYKRKGDSQATLPQTGSSDWAATGLGLATATMAVLLFSKKHRKKIIGLVLIGAAGQSLLVPIEVLALQNKELQAYNQTLAVSNKEDLAKGVIAIDGYEYVGYLRYSAKPELEQPLENTLQGLESSIKEDNTVSQGTADRDSKGISWKKGTQEPGHEGEAAVQPANPEYTGPISAKGTQESGHEGEAAVQPANPEYTGPISAKGTQESGHEGEALVQPANPEYTGVISANGTQEVGHEGEALVQPANPEYTGPISANGTQEVGHEGEAAVQPVAPEYTGSISSDTTSANGTQEVGHEGEAWVQPANPEYTGPISANGTQEVGHEGEAVVQPANPEYTGPISANGTQEVGHEGEAVVQPANPEYTGPISANGTQEVGHEGEAAVHPANPDYTGKLEAKGTQESGHEGEALVQPTNPEYTGKLEAKGTQESGHEGEAAVQPENPVHTPVVGSVTETEMQAIDYPIEVITDDSKYVDEEVVEQEGQKGSQEIQKIYQTIDGVKVGEPTIVSGKVIEVPQPRKLRRGSKPLDGTTTEESIVELPFKEIVQEDDTLEKGTLQVVQDGQKGQNKITKVYKTYKGNKTSEAPTVTETVLVPVQDRIVHKGTKVSEKPVLTLTQIDKDDLGRSAKLSYNLTNPGSAAITTIKAVLKQNGQVVQTLDIPSTTLTADLTNLDYYKPYTLTTTMTYDRGNGEENQVLADQTLQLDLKKVELKDFARTDLIKYDNQTEVDETRLAAVPQDLTNYYLKMTSADQKTTYLAVKTIEETTVDGKAVYKVTAAADNLVQRDAQNHFAQTYSYYIEKPKASQANVYYDFAELVNAIQANPSGEFRLGQSMSARHVVPNGKSYITTEFTGKLLSDGDKRYAIYDLEHPLFNVINGGTIKNINFENVDINRPDQNQIATVGFNLKNKGLIEDVKVVGSVTGNNDVAGIVNKIDEDGKVENVAFIGKINSVGNNSTVGGIAGSNYMGFVNRAYVDATITANNANASMLVPFVTYMLNSWKSGTKAKVTNSVAKGVLDVKNTRNVGGIVAKTWPYGAVQDNVTYAKVIKGQEIFASNDVNDEDGGPYIKDLFGVVGYSSAEDGTGKDTKSPNKLKHLTKEEADKRVEGYKITADTFVSEPYALNTLNNVSSQADFANIQDYKPEYKQAYKNIEKFQPFYNKDFIVYQANKLAKDHNLNTKDVLSVTPMKDSNFVTDLSDANKIIVHYADGSKDYFKLSESSEGLSNVKEYTVTDLGIKYTPNIVQKDHSSLINGIVDILKPIELQSDPIYQKLGRTGPNKVNAIKNLFLEESFDAVKAKLTNLVTKLVQNEDHQLNQSPAAQQMILDKVEKNKAALLLGLTYLNRYYGVKFDDVNIKEIMLFKPDFYGKNVDVLDRLIEIGSKENNISGSRTYDAFGEVLAKNTLSSDLTDFLNYNRKLFTTIDNMNDWFIDAAKDKVYVVEKASQNEGVGEHKYRVYDNLSRGLHRKMILPLLNLDKTEMFLISTYDTMSYGTANKYNTTLEKLKPEIDLAAQRQINYLDFWQRLAADNVKNKLFKDIVNPVWEGFYVWGHGWPGWPERYGQFKNSTEVYAPIREIYGPVGEYYGDNGAMAGAYAAIYDNPYDNRAKVTYVMSNMISEYGASAFTHETTHINDRIAYFGGFGRREGTDVEAYAQGMLQSPATQGHQGEYGALGLNMAFERENDGNQWYNTNPNKLNSREAIDRYMKGYNDTLMLLDSLEGEAVLSQGKQELNNAWFKKVDKQLRGNSKNQYDKVRALSDSEKAISLTSIDDLVDNNFMTNRGPGNGVYKPEDFSSAYVNVPMMSAIYGGNTSEGSPGAMSFKHNTFRLWGYYGYEKGFLGYATNKYKQEAKAAGKNTLGDDFIINKISDGQFNSLEDFKKAYFKEVKEKASHGLTTVTIDGTSVSSYDDLLALFKAAVAKDAASLKTDNSGNKSVSTSHTTKLKEAVYKKLLQETDSFTSSIFK
>NZ_CP013216.1|WP_021143842.1|1485825_1489470_-|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein
MRDMFNKRQRFSLRKYSFGVASVLLGVSIFSNAQGAQADETVAPTTAGMETTAEPDVVVEQSTPTTASVAPATTENAPSSVSTVALASEQPQSAAQESQATSTTSQTAASSEAASQAASQASSESVAATASSVATSAQSLSSTAVAEAPVAGQVSAQTSAAASVATAAETASAESTTNAVNSVLKVATSELAVTSSELTAAEASLNSENLINAMGLAVSNRSLRTADAVAVLTNAGASSTNPDLTNLGYKLAYLPERQQYFVNIDYINHLKVGRDNRGVMRPYDYITNGSYMVVVNYANLGIIDYVDEAGNKIPGSSTYRINNSTETITANGKTYNKIYDAGVTELPPVPAGYRIKYASADKSKANAYVDVLKSERQYDYNNGIATIRSERAWDRNQSRVVDLVQFANGSQGLDASIDANGGGQYLAPGYRYHIIVEKDTKDVTKATSQTVTYTGADTKTPAANTQNDFSFNGKEDPTTNTTTWTETTHTYGTVKTPVVTGYYADKAVAGGKTVTPDAPNVTDTVTYKAFGKFIAVDENGNPIPGVSTTAYTNDPNDATKMIAIDKTLPSIPGYTVKVIPASPSNPGEDTRVVYVAIVNDVTKATKQTVTFQGAGDKTPAADVKSDYTFAGKDNQATGKVTWNETSHTYGTVKVPVVNGYFADKAVAGGKTVTTDAPEATDTVTYKAFGKFVIVDENGNPIAGVSDTAYINDPNDPTKMIAVDKNLPTIPGYTAKVVPATPGDLSSDTKVVYVKNDQKASVVYRDETSGSTLETVALAGKSGEAVNYSTAERIKHYQDLGYVLVTDGYPAGASFDLDSTVDQAWTVSFKRVALDFNPDNAHEPGTPIYPNQPNGPKWPAKDAYLKDVTYTVHYASKDSDAKLPADSVQKAQWKRSLTLDSVTGDILTTGEWKADKTKFDLVITPMVNGYFADKGRVASQDVTMDSKVETVTYTKFGKIIAVDEKGNPIPGVEAVTYTNDPNDPTKAAMTLVPEVKGYKADKTGVTPSNPGEDTKVVYKVVNAEPAKPTVNKEVGTIVVIYRDEYGNQIKMPLVITNSVGSEVNVHGDRYIYRNGVKYELIRQEGKSTDKMTEGQTVVTYIYRKVEDGSTPSNGNGGQSGSSTSKAVKATSNGSKGSKGSGSGSAADGASDGKGSDKKKSGNKDGKKADGSDKAKEGDEQLPVTGESDNNLAAMGVVVMGLMSGLAAMNRRKNQD
>NZ_CP013216.1|WP_021143843.1|1484433_1485642_-|exonuclease-SbcCD-subunit-D
MKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEKVDGVIIAGDLYDRAVPPVDAIKLFNKTLARLVLEEQIPVYAISGNHDGAERLHFGRDFFQHQGLHLSTRLEEAFEPIELEACQIFLLPFIDPIDARIYYKDDENKEIQGIGDALAYILEDMEKAFDPDKAHVLVAHFAVSKKDDSDGQSLRELMLSETSNTVGGLTNVTSDLFKAFDYVALGHIHTRFASPSQRVQYSGSPVTFNVKEAKRREEKGVYILDLDATGDLSQTFHPLEVKRPILALQEPFETLMSPEFYKEQPCQKAWFAFDIQLFSRKELEGINVRARLEEIYGTDIVEITFSRLGDVREESLTVDQHLKDLEMQSPQEIVSDFYQTVTGGDVLSERQTALVESIFEEIGRSRQ
>NZ_CP013216.1|WP_021143844.1|1481257_1484437_-|SMC-family-ATPase
MRPVQLELTNFGPYRKEVINFTQFDHAPLFLIGGDTGAGKSTLFDAMTVALFATTSGDRNVEEMRSTFASPEDDLTKVTFYFQQGKHLYRIERVLQQERAKRGGGTTMQKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFSRFLKEDSKTKTQILKKIFGTGIFDRFQKSLEERLRQSNKDMDKRQAQLDGHFASQVWSEEELAVLTQTPASEKLARLEELLVQRQDNLEEQKSILKDAHEDLAKLQKSLQTAQDLAKIFQELKQAKERYCLEIEEGAQEQAEAKAHLDELQFAQGLQETISSLKQYQKQLLQLEQDLEIAQEELSEKQQAFEGVKAQKEALAAQSKDSLQKEEELETWKEDIIYAQSLVREQEKIKRSRTNYKQLEETYQQASKKIELLNQSLSELEANRLSVDSLHEAEKLLQSVGYSVDKQLAQDLKEIEGLNQELAKTEKRQQGLSLDIDQAQESLKELEDQLATTLASRRQLMIAQLQAELEDGQPCMVCGSFDHPKVDGTQADEAALKELMDQVEALQAQKERQVATLSNRQATLSEVESKRQDLLDQVAKVKLTLEKHYLELQEQVKGQFDFDFAEDYEADCGQTLLRKVEQYYQELHKRFDKEEADCLHYQDELAKVQEKSIDLAKAYQEAKAALDQAKERLKELQEAHQELESVEVYQERISLAKQELDLYNKQVKENSEAYNQLHADIQGIRGQLESLTKSKENASQETKRLSAELNQSLMAEGALTNDLEQIQLWLLEVNKQAIPELQAQLTSYQTLKQELQAQIVKGQELIEDQEKPDLGNLTQAVEDCQESYDKQLAQVSVMEQGLKDATATYQAAKTLQDSNQEAFKAHQELSDLVKVVKGENTALTGRLNLEVYVIRQYFQQILDYANANYIGLLMDNRYSFVLSEEGRRARDHFGLDINVYDQLTGSERSVKSLSGGETFIAALAIALSLSEVVQNTSKGAVVEALFIDEGFGSLDKEALTKAIAVLEQIGENRVVGVISHVDDMKEGIAQQLAIIKSHDGSSSIKIVDKG
>NZ_CP013216.1|WP_021143845.1|1478779_1480873_-|glycosyltransferase
MTEKISVIIPVYNVENQLQTCLDSVLGQTYQNLEIILINYGSIDNSDAICRSYAARDSRILYFKKDNGGLSDARHIGIRQAKGAYVTYVDAEDWVESTYLEELYKTLQAHKADIAVANYSVYKESEDLFYFYIKDEDYYEQVYSPAQIIDGLFEETNNINIALISATGKLYKRSLFNDLLFPKEHAGEDGFFNLKAYLMSERTVYLNKGLYVYRESPEMPSATWMQDWMMTLVYAMEERLAIVASHGFPLEKYMVTYRQMLEACLKNVEEQGLTDSDAYRSIQEKFQVLSLAPQRYETKKRAIVLAANYTYVDQVLTTIKSIVFHHRNIRFYLINDDFSQEWFRGLNRHLAAFGSEVINCRVDSSHIKQYKTNSNYASYLRYFVADFVSEERALYLDSDMVVTGSLEDLFTLDLQGRPLAAVRDYAIQVQDRQAMFDAGFMVIDTAYWKQYNMRRHFIDMTSEWHDKVPFAEQSILNMVFRNNWLPLSFDNNYAVTKSSLAGFHLPNGQDYPKVVHYASHRKPWLPLACQAYREVWWFYAQMDWSGVAENAALLPLSEDMIYPKGRPFTCLVYTNISEIPHLTDLISALPKVQFKIASRQHVADKLAQLITYPNVTVYSAIAGLNGLDLELLRTSDLLLDINPGRKVVEILDAFRFENKPILGFEDLKSTKHNQQTYSRDRWKEMAETIRQMRKKSL
>NZ_CP013216.1|WP_021143846.1|1477458_1478685_-|accessory-Sec-system-protein-translocase-subunit-SecY2
MKKISQSIITKRVLWTLFFLFIYCLGNQLVLPFVDLKNANIFGGAIGSLAFSSAMMGGNLRSMSLFSVGLSPWMSAMILWQMFSFSKKMGLKNLPIEIQDRRRMYLALGIAIVQSLAVSLNLPIVSGVNASLAIFMNTILLIAGTFFLVWLSDLNSLFGIGGSIVILMASMMANLPYQIMDSIEKLGIGWDVLLPLILFSLVFLYISGVVQRARYRISINKINIHNRFKQYSYLDIMLNPAGGMPFMYAMSLVSIPQYVFMLIQFIHPENKWTSGAIKALTVGQPLWLVVYLVMLFVLGLAFAFVNVSGEQISERMRKSGEYIYGVYPGQETSAYINHLVLRLGFIGALYMLFMAGAPMLIILVNPDYLQLSMIPGTFLIFSGMIYNVNEEMKALKLNTSYTPLFENV
>NZ_CP013216.1|WP_021143847.1|1475786_1477358_-|accessory-Sec-system-protein-Asp1
MYYFIPAWYGQTDEFWKTVIDPWYRIRQKIEFDDSLHQVRIFQDEDLAPQLLLLAYQPHLRYFLHRHDVLEVGYTAIFDLIQGITDEDMKNLQVTDLEWPEGATFVHTPFAIVVQCQHKRYAEIEFGSEGFIGMIRYYKDEQIIREDIYDDRGFISSSLYYEGGQPSYRNYLNAKGVWQLCHFFDGRGIVANPRTEGRFNKSYYSNLSEVIWEFLTKFLDEKVEAEDRFVIASDLRHNKHLFEHLPADNTKILTWFAERNQDDSIDTYEVFLPQVDLLIADRYDYLEQLQVAYPEEAKKLKHMASFDTRLALGTSQRVKESKIFYQVDFDQLDLEAIYQVLAFVAKYPKTQVEFGAFNANPEQLGSLQNQVEKMIEERLSPDAFEEVVESSGAENKLEENNEIVSRFSFQDLRDETALIKALQFTRLIVDLSKEPNRYTQIAGISAGIPQINRVASEYVTHQENGYILKHLSDFEKGAYYYLGQLNNWNRSLIYSIEKIKENTGDRLVQKWENWLKEEQNDQG
>NZ_CP013216.1|WP_021143848.1|1474261_1475800_-|accessory-Sec-system-protein-Asp2
MTKDNRLKILQVGSSNWSENQEIPENMKWYYCNLGQLETLQETIEEDEIKTFTAVIVDSLAGLEELMTIKEHLIPHTIFFDQTIEVPDESLLQFLKEVCAVPTDFSNQGQLLFTLSKALFSGQYGDKMFPFTTQVNPNFTGQVTYHGYENVILKGEYGQDFSPVLDWTYNVRASKENPIELWLEFEKEETCECRLILNLLPEGSVAGIFKTYIVSEEEMRKGAIVLDEDTTFLLSASLEMKGQGQITIGGLHQRLTRFQFGKFVLGGGILHDSKRQEINYFFYPGDFKPPLSVYFSGFRPAEGFEGFGMMKGMGTPFLLFSDPRLQGGAFYMGTEELENSIKDTIQHYLDYLGFDNSQLILSGMSMGTFPSMYYGADFEPHAIIMSKPLANVGTIGNRARLLAPEVFPTGIDVLHLQTGRLDNEGVEALNQKFWDKFEKADFSDTTFGLSYMKDEDMDPTAYEDITKSLYYSGAKILSKGTSGRHNDDSYTATTWFVNFYRMILENDFGRKE
>NZ_CP013216.1|WP_021143849.1|1473812_1474259_-|accessory-Sec-system-protein-Asp3
MFRNKKSEILWGLNHKAYMYGSKIVKRQDGSVQFYNPLVPSGTEIQSWVAIQNYQAGRTQPALPLLKKGHSYDLTANLEAVPTGSVFLKVSFLDRYGNEIKQLIEKSTHMTFIYPHEAYTYRISLLSAGVKELDFYSLKLEETGEEHV
>NZ_CP013216.1|WP_021147312.1|1471444_1473820_-|accessory-Sec-system-translocase-SecA2
MFKQLNPILPVKEILKEINGLADEIAGLSNLELKNKTQEFKERLAQGESLDDLLPEAFAVVREADKRVLGMFPYDVQVMGGIVMHQGHIAEMNTGEGKTLTATMPVYLNALSGEGAILVTTNEYLAIRDAEEMGQVYEFLGLTIGVPCVEGSNEMEPAEKRAIYQSDIVYTTNASLGFDYLIDNLASNQDGKYMRPFNYAIVDEVDSVLLDSAQTPLIISGAPRVQSNYYGMMDTLMTTLVEGEDYIFKEEKGEVWLTTKGAKAAENYLGIGNLYDEENSTFARHLLFSLRAHLLYKKDKDYIIRDGKKGPEVVLLDKSTGRLLELTKLQGGLHQAIEAKELVALSQETRAMASITYQSLFKKFKKISGMTGTGKVAEKEFLDTYGMKVIQIPTNRKKQRIDYPDKIYATLPEKVFASLEYVKHYHEKGNPILIFVGSVEMSELYSSLLLREGIAHNLLNANNAPREAEMIAESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLVVIGTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKYGPSWVHRTYKEYAISDHIEPKELTGRKYRKLVQKAQEASESSGRTSRRQTLEFAESMNIQREMIYAQRDRLIFHNQGLDTVIDEVLDDFIDQAVADEDFSKAENLYHFILRNISFRINEIPKDLDLNNREEVLELIYQFAYRELEAKKQELKTKELNEYFQRLAMLKAVDDNWVEQVDYLQQLQMAIGSQQLSQKNPIVEYYQEAYKGFEAMKRQIRKDMVRNLLLSQVQVTKKGDIISHFP
>NZ_CP013216.1|WP_101799703.1|1510035_1511307_-|hypothetical-protein
MNRLSCSCLHLPPNVTCLDCTLSERFCQMKIKNPTLLDRRCTLSIVSTYAILKAILKMEIVMENKFVKKPTPKGDKSTRIVFIGLLVALLFIIAGTAIFFAVNSSSKATKGLAASSKSSTTVYSGSNAEDPLFKITLKTFGDNKEFLLVTPNPGHDRNMFNIVGVAGQYLVTQEYKGGESGKKNAKGETLYKYDYFNIYMYDTEKPNQKPKQIDLLKLAKKAGDEDYLNQASLRLFMLNEQAYLQMPFGASSADFASNKKYLNLKTQKIEEMNIPANSNTLDSELDYANVDMRKTLEPFGLEMWPDATNGKDLDYPRETPIASLPALYYISEKDRSLNMDSTNFAKEHKDAYESIKTKHARIYTIPSKVNNETWFNTLLHWVAPEGQDAYELPVRAFRPTQEEGKVKSYQELQTWNDNHIRKK
>NZ_CP013216.1|WP_021143837.1|1511561_1513085_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MIQIQHLTITHTKDLRELVHDLNLTIATGEKVAIIGEEGNGKSSLLALLVNPKAHFDHLSYEGTINKPDSPQVYIPQQISDDLQSLTLNDYFFADTYDLDYATLYRLADELHFDSERFASSQLVSSLSGGEKLKIQLIRELARPHDIIFLDEPSNDMDLTTMTWLKNFIKHSDQTIIYISHDEDLLSQTADTIIHLELLKRRRQARTSVEHLDYDNYSQQRTDAFQQQMQQAKTEKKAYDKAMAKHRRIKQNVQTTLRNTHDSTQGRLVAKKMKAVLSQEKRYDRLAQDMTQIPDKEDSIELFFSHITPLPQGKYLLNLDKKQINIAPHLTIDHLKLSLKGQEKIGIVGDNGCGKSTLLHFLYQELSKKTDLTIGYMPQHYDTILQNDLSPIAFLSKTGDKTEREIISSHLANLNFSHDEMNHAIDDLSGGQKGKLLLLHLVLESPQLLILDEPTRNFSPTSQPQVRQLFENYPGAILTVSHDVNYLRQVCQKIYRLDSHGLKEVEI
>NZ_CP013216.1|WP_021143836.1|1513180_1515049_-|ABC-transporter-ATP-binding-protein
MQNKKKANWGSLARLLRFLWQDYKLSLSIAFVLIVVASLATVNLTASIQSLVDVYVQPLLKSGSHDFGPLLRFLTSVAVFCLIGVIANYVSSLLMATISQDSLRSLRNQLFARMQKLPVRYFDTHQHGDIMSIYTNDIDALRQAVEQSIPQLLQTTITIIGVTVTMLTVSPLLFIVVLIMVGIMFMVIKNVSAKSGRYFGEQQKNLGIENGFIEEMMSGQKVVKAFVHEEESMADFDKINKQLFESSYLANRYANVLMPILGNLGNVSFVLTALVGGLFALNGVGGLTIGGLMAFLQLNRSFNGPITQVSQQLNFVLMALAGADRIFDLLDEAEEVDQGKVTLVNYELVDGQMVATDKKTNHWAWKHPRPNGDYELVELVGNVVFQDVDFSYDGKKQILHDVNLYADKGQKVAFVGATGAGKTTITNLINRFYDIQSGVITYDGIDVKLIEKNSLRRSLGIVLQDTHLFTGTIAENIAYGRADATREEILEAARIANVDSFVQHLDNGYDTVLTDDGAGLSNGQRQLIAIARAALANAPVLILDEATSSIDSRTEKMVQEGMDRLMEGRTVFVIAHRLSTIVNSDVIMVMDHGRIIERGDHDSLMEQGGTYYRLYTGGLEID
>NZ_CP013216.1|WP_021143835.1|1515038_1516784_-|ABC-transporter-ATP-binding-protein
MFQTLIPQIKEYKKPSILASLFMTLEVMFEISIPFVMANLLDKGVQQSNMSNIWLYGGLMLVCAFLSLFCGMQSARYAAFASAGFAKNLRQAIFKKVQTFSFENIDKFSAGGLVTRMMTDVTNVQNSYQMIIRVCVRAPLNLIFAIAASFLINAEMAWIFVGVTIFLGVVLAIITKIVYPLFTQVFEAYDNLNNSIKENITNMRVVKSYVKEQEETDKFKKASRRIYKMFMRAIRVVIMSNPAMMLSMYASFLMISWFGAHLIVGGSLTTGELTSMFSYTMTILMSLMMFMMIFVMLSISTASVERIDEVLSTEATIVSPENGLTEVSDGSISFDHVDFSYTDENGDKTHVLKDITLDIKSGEVIGILGGTGSGKSSLVQLIPRLYDVEEGQVRVAGHDVKDYDLDSLRKQVAMVLQTNVLFSGTIKENMRWGNKQATDEEIIEACKIAQADEFIQEFKDGYDTKIERGGANVSGGQRQRLCIARALLMNPKILILDDSTSAVDTKTDSLIRRGFASSLKETTKIIIGQRISSIQDADRIIVMNDGRIDAIGTHDDLIANNAIYREVYKMQTQGKGVADAE
>NZ_CP013216.1|WP_042762414.1|1517647_1519912_+|bifunctional-glutamate--cysteine-ligase-GshA/glutathione-synthetase-GshB
MTINQLLQKLEPTSPILQANFGIERESLRVDRQGKLAHTPHPSCLGARSFHPYIQTDFCEFQMELITPVAKSTTEARRFLGAITDVAGRSISKDELLWPLSMPPRINAQEIQVAQLENEFERHYRNYLAEKYGTKLQAISGIHYNMELGKDLVEALFQESDQIDIIAFKNALYLKLAQNYLRYRWVITYLFGAAPVAEQGFFDQEVPEPVRSFRNSDHGYVNKEKIQVSFASLEDYVSVIENYIEQGDLIAEKEFYSAVRFRGQKVNRSFLDKGITYLEFRNFDLNPFERIGISQNTMDTVHLLLLAFLWLDAPENVDQALAQGHALNEKIALSHPLEPLPSEAETQNIMTALDQLVQHFGLGDYHQSLVKQVKDAFADPSQTLAAQLLPHIKDKSLADFALDKALAYHDYDWTAHYALKGYEEMELSTQMLLFDAIQKGLHFEILDEQDQFLKLWHQDHVEYVKNGNMTSKDNYVVPLAMANKTVTKKILSNAGFPVPAGDEFTSLEQGLAYYPLIKGKQIVVKPKSTNFGLGISIFQEPASLDNYKKALEIAFAEDTAVLVEEFIPGTEYRFFILDGRCEAVLLRVAANVVGDGKHTIRELVAQKNANPLRGRDHRSPLEIIELGDIEQLMLTQQGYAPDDILPEGKKVNLRRNSNISTGGDSIDVTETMDSSYQELAAAMATSMGAWACGVDLIIPDKTQPASKEKPHCTCIELNFNPSMYMHTYCAEGPGQAITPKILDKLFPEVATSQT
>NZ_CP013216.1|WP_021143832.1|1519973_1520570_-|hypothetical-protein
METKKTETLDSVLVAKNFYRVRDAYAIKLYGQDEGMSFDVAGQRLFGSNIAIKDGLLYGSSLGDLTIEAYFQGEASYLLEATQKLPVDKNRIKSNHYSQDIVLNKVWTSLENQEFSNSIITQFQDKTLLKLRISYNKDFLPTKIQGFYNSQTFNGWQDLFYIDYPYSDQEAFNQAQDAYIQHIQYMETHPEEEAGEFG
>NZ_CP013216.1|WP_021143831.1|1520550_1522080_-|DUF1310-family-protein
MKKVILQYLASALAVILILGLVVFNRQRNHSLVKKVKDPEISYIYKDSLENLDRLALSQAGIIQSYQLDSLSVRKEDGKIHLVLHINHSYDMQVNLVLKSDIYGDLSVVQATPSKALKLALEDESYQKRLTLISQKADAIISRDHWDQGIKPAYVAQVRSKMKKTSLNQLEKVLQEIDQESKEVGSDTYTSFFQASQLPNHDKLNLVMEHMQVYVDKYQFLQLGKSGYKFSKKLEPTSPFYSYFREAIMETYQTDLGLGVDELGIKLHLFRSWIDKQSMDYIKTNYKGKTDLDKLLAYSKDKKIKLDYTTGASYHNRSLGDFTYPENMKIQLPQTSVMGPYGVSNSRFIEFIVNMDTGKFVSEWNVYKKRKDGSIDSNPKHYKIEDGADIADTDSANYGLSKGLNADLPAYLNNSHTYLDVRHPADNAIRRKMVRKWKNAKNVLNGGRYADIVKKGGLKDLETWKQVKAEDRLQVYNAYLDYIRSHLVLNGFDSFYQETYNTQGGDKKD
>NZ_CP013216.1|WP_021143830.1|1522187_1522748_-|GNAT-family-N-acetyltransferase
MALRSQLITKEFPELDRVERLNNEAFPEEERIPLIDFLKLDGRDDYHFFAFYDEDDFVGFASVLYNAKVFYVSFFAIVPQMRSHGYGSEIIDKLVDFYGPSRSMVLEVERLDEPNDNPEQRVARWDFYKRNGFKTSNAFLEYEGLSFEILYRGNHFDEKAYRDIFHKLQENAYFDFSIKHRRLSDL
>NZ_CP013216.1|WP_021143829.1|1522959_1525365_-|glycogen/starch/alpha-glucan-phosphorylase
MQLENLTKEQFIRDFKDTLHQEQLIKVAKATPTEIFTALAGLIRKYYTNTWIERNHALSDNQEKIAYYFSIEFLPGRMLETNLLNLGILDLVKEGFAELDIDFREVVEAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVDGYQVELPDGWFGSTGNVWETRKDHDIVYVKLFGDVVLESNEDGRFVPTYKNAQVLRAVPYDVPQIGYQNGVINNLRLWDVEIPEEYELDYPTLEARRRVKDITAILYPDDSTIEGKELRLVQEYFMTSAGLQTIIKSYLKMGLPLKDIHEKVSVHINDTHPAVAPAEFMRLLLDEYGLSWEDAWNATVKTMSYTNHTILQEALEKWDQQLFKRVLPRVYQIILEIDNRYIAEMAGRGIAADVIERTRIVKDNQVHMANLAIIGGHSVNGVAKLHTELLKEDTLHDFYTIYPEKFNNKTNGIVQRRWTQIAAPELSAAIDDVIGDGWRNDIHELENLTTYLDDKEVLNQFYQVKKTAKQRLADYIKETTGVEVSTDAIFDVQVKRLHAYKRQLLNLLHIIKLYWDLKDNPDKDMVPRVFIFGAKAAPGYHFAKSVIKLINEVANLVNNDESLQGKLKVVFLENYRVSLAELIIPAADVSEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGDENVVIFGMDKDEVYEHYARHDYYSRAVYENNPVIRRVVDTFVNGTIPNAQSEGTEIYEALITHNDEYFLLEDFAAYVEAQEKIDALYRDHDKWARMSLANIAKSHKFTSDDTITEYAKEIWELKK
>NZ_CP013216.1|WP_021143828.1|1525690_1527121_-|glycogen-synthase-GlgA
MKILFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVAVILPYYDVVSAKFGDQVEDLGFFYTNVGWRRQYVGIKKIVRDGVTFFFIDNEQYFNRGTVYGEWDDGERFGFFQMAALELMEKVDFIPDVLHVHDYHTAMIPFLLKEKYHWIQAYQGIKTVFTIHNIEFQGQFDSGMLWEIFGVGYERYADGTLRWNDCLNWMKAAVLYADRVTTVSPSYAGEIQTPEFGKGLDQIMRMESGKLSGIVNGIDTDLLDPETDTHIPYHFSVDDLSGKAKDKAALQERVGLPVREDVPLIGIVSRLTDQKGFDLVVNELHNILQHDVQIVLLGTGYSDYENSFSWFAHAYPEKMSANITFNLELAQQIYAGCDIFLMPSAFEPCGLSQMMSMRYGTLPVVSEVGGLRDTVEPYNPVTGSGTGFSFGNFSGYWMVQTLEKALDVYENNADAWKQLQHNAMTRDFSWDTASLAYVDLYKQLV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP013216_4	4.2\|1496734\|21\|NZ_CP013216\|CRISPRCasFinder	1496734-1496754	21	NZ_CP013216.1	542567-542587	2	0.905
NZ_CP013216_4	4.2\|1496734\|21\|NZ_CP013216\|CRISPRCasFinder	1496734-1496754	21	NZ_CP013216.1	944295-944315	2	0.905

1. spacer 4.2|1496734|21|NZ_CP013216|CRISPRCasFinder matches to position: 542567-542587, mismatch: 2, identity: 0.905

tggtggtgttggtggagtcgg	CRISPR spacer
tggtggtgttggcggagttgg	Protospacer
************.*****.**

2. spacer 4.2|1496734|21|NZ_CP013216|CRISPRCasFinder matches to position: 944295-944315, mismatch: 2, identity: 0.905

tggtggtgttggtggagtcgg	CRISPR spacer
tggtggtgttggtggtgttgg	Protospacer
*************** **.**

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

324650 : 330096

Streptococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021143582.1\|324650_325415_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.9e-15	24.8
WP_002883761.1\|325414_326125_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.3e-15	26.9
WP_002890017.1\|326259_326919_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	1.5e-66	59.2
WP_002883742.1\|327067_327994_-	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	9.4e-144	81.8
WP_021143583.1\|328095_328722_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	5.1e-69	61.4
WP_021143584.1\|328776_330096_+	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	3.4e-123	52.5

DBSCAN-SWA_2

605540 : 616441

Streptococcus_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021144480.1\|605540_606656_+	glycerate kinase	W6LM47	Streptococcus_phage	9.2e-138	86.6
WP_021144479.1\|606686_607142_-	YueI family protein	W6LLD2	Streptococcus_phage	2.3e-66	83.4
WP_002886048.1\|607347_608652_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	1.4e-246	99.5
WP_014634140.1\|608801_608987_-	hypothetical protein	W6LMT3	Streptococcus_phage	4.3e-24	91.8
WP_037620394.1\|609161_611348_-	LTA synthase family protein	W6LM83	Streptococcus_phage	0.0e+00	95.0
WP_037620392.1\|611509_612673_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	4.2e-210	94.3
WP_021144476.1\|612669_613347_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	1.1e-114	93.3
WP_021144475.1\|613336_614194_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_013990891.1\|614206_615274_+	3-dehydroquinate synthase	NA	NA	NA	NA
WP_021144474.1\|615274_616441_+	chorismate synthase	A0A291AU41	Pandoravirus	3.5e-39	34.7

DBSCAN-SWA_3

625896 : 636519

Streptococcus_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021144466.1\|625896_627252_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	D0R096	Streptococcus_phage	4.5e-203	78.7
WP_000873143.1\|627641_627812_+	hypothetical protein	A0A1X9I6E4	Streptococcus_phage	3.7e-22	98.2
WP_000417519.1\|628197_629415_+	macrolide efflux MFS transporter Mef(A)	A0A2K5B2B5	Erysipelothrix_phage	5.1e-198	90.6
WP_000420313.1\|629534_630998_+	ABC-F type ribosomal protection protein Msr(D)	A0A1B0RXA0	Streptococcus_phage	3.7e-251	97.3
WP_001072467.1\|631115_631415_-	hypothetical protein	A0A1B0RX98	Streptococcus_phage	1.8e-48	96.0
WP_000567222.1\|631401_631770_-	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	1.1e-58	97.5
WP_000806926.1\|631782_632118_-	hypothetical protein	NA	NA	NA	NA
WP_001813542.1\|632114_632360_-	hypothetical protein	A0A1B0RXA7	Streptococcus_phage	2.6e-37	98.8
WP_021144464.1\|633270_633723_+	ZIP family metal transporter	NA	NA	NA	NA
WP_008534149.1\|633723_634071_+	ZIP family metal transporter	NA	NA	NA	NA
WP_002890511.1\|634085_634448_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002890512.1\|634431_636519_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.2e-114	36.1

DBSCAN-SWA_4

1140658 : 1151322

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021144069.1\|1140658_1142221_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.4e-19	30.3
WP_021144068.1\|1142507_1143092_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_021146799.1\|1143376_1144396_-	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	6.0e-27	25.5
WP_002891080.1\|1144557_1144839_-	hypothetical protein	M1PG86	Streptococcus_phage	4.2e-23	58.4
WP_037603164.1\|1144816_1145194_-	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	7.7e-20	45.0
WP_021144065.1\|1145190_1146606_-	Y-family DNA polymerase	M1Q231	Streptococcus_phage	3.6e-195	70.9
WP_021144064.1\|1146719_1147571_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_021146796.1\|1147583_1148213_-	amino acid ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.5e-31	39.7
WP_014634576.1\|1148221_1148863_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002891088.1\|1149063_1149396_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_021144061.1\|1149513_1151322_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	5.6e-100	39.2

DBSCAN-SWA_5

1200025 : 1214104

Bacillus_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021144023.1\|1200025_1202662_+	calcium-translocating P-type ATPase, PMCA-type	A0A1J0FA34	Only_Syngen_Nebraska_virus	1.8e-83	29.4
WP_021144022.1\|1202810_1204079_-	D-alanyl-lipoteichoic acid biosynthesis protein DltD	NA	NA	NA	NA
WP_002891149.1\|1204071_1204311_-	D-alanine--poly(phosphoribitol) ligase subunit DltC	NA	NA	NA	NA
WP_021144021.1\|1204328_1205576_-	D-alanyl-lipoteichoic acid biosynthesis protein DltB	A0A125RNP0	Pseudomonas_phage	7.9e-21	29.0
WP_004182015.1\|1205572_1207123_-	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9KZV5	Tupanvirus	1.7e-41	28.9
WP_002885174.1\|1207131_1207263_-	teichoic acid D-Ala incorporation-associated protein DltX	NA	NA	NA	NA
WP_002890057.1\|1207524_1208490_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	1.2e-45	45.0
WP_059749084.1\|1208486_1209164_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_048790626.1\|1209347_1209821_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	7.6e-17	33.3
WP_021144020.1\|1209984_1211733_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.0e-54	31.3
WP_021144019.1\|1211722_1213462_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.7e-45	27.5
WP_037620261.1\|1213492_1214104_-	lysozyme family protein	A0A223LKM8	Bacillus_phage	7.1e-23	42.0

DBSCAN-SWA_6

1354744 : 1435597

Paenibacillus_phage(50.0%)

transposase,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002890057.1\|1354744_1355710_+\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	1.2e-45	45.0
WP_021143909.1\|1356323_1357628_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.8e-08	24.4
WP_021143908.1\|1357624_1358278_-	response regulator transcription factor	NA	NA	NA	NA
WP_037620241.1\|1358349_1359726_-	ABC transporter permease	NA	NA	NA	NA
WP_021143906.1\|1359739_1360372_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.6e-20	31.8
WP_021143905.1\|1360387_1361647_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_059749213.1\|1361953_1363438_+	DUF1846 domain-containing protein	NA	NA	NA	NA
WP_002885337.1\|1363659_1364004_-	hypothetical protein	NA	NA	NA	NA
WP_021143902.1\|1364306_1365398_-	glycerol dehydrogenase	NA	NA	NA	NA
WP_021143901.1\|1365541_1366525_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_021143900.1\|1366539_1366914_-	PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM	NA	NA	NA	NA
WP_021143899.1\|1366917_1367493_-	dihydroxyacetone kinase subunit L	NA	NA	NA	NA
WP_021143898.1\|1367524_1368514_-	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_021143897.1\|1368840_1370106_+	threonine/serine exporter family protein	NA	NA	NA	NA
WP_021143896.1\|1370208_1371042_-	metallophosphoesterase family protein	NA	NA	NA	NA
WP_037620239.1\|1371092_1371416_-	hypothetical protein	NA	NA	NA	NA
WP_021143894.1\|1371405_1372011_-	DUF1648 domain-containing protein	NA	NA	NA	NA
WP_002891308.1\|1372000_1372276_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_021143893.1\|1372253_1373000_-\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_021143892.1\|1373201_1373528_-	hypothetical protein	NA	NA	NA	NA
WP_021143891.1\|1373800_1378540_-	glucosyltransferase	NA	NA	NA	NA
WP_021143890.1\|1379404_1381390_-	hypothetical protein	NA	NA	NA	NA
WP_021143889.1\|1381871_1386557_-	hypothetical protein	NA	NA	NA	NA
WP_002890057.1\|1386805_1387771_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	1.2e-45	45.0
WP_059749084.1\|1387767_1388445_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002891962.1\|1388628_1389102_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	2.0e-17	33.3
WP_021143887.1\|1389633_1390965_+\|holin	choline-binding protein A	NA	NA	NA	NA
WP_021143886.1\|1391165_1394348_+	hypothetical protein	NA	NA	NA	NA
WP_059749215.1\|1395079_1397935_+	glucosyl transferase	NA	NA	NA	NA
WP_059749217.1\|1397992_1401556_+	glucosyl transferase	NA	NA	NA	NA
WP_059749219.1\|1401610_1404142_+	glucosyl transferase	NA	NA	NA	NA
WP_021143879.1\|1407560_1408154_-	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	NA	NA	NA	NA
WP_021143878.1\|1408154_1409027_-	pyridoxal 5'-phosphate synthase lyase subunit PdxS	NA	NA	NA	NA
WP_021147282.1\|1409357_1412156_+	hypothetical protein	NA	NA	NA	NA
WP_021143875.1\|1412470_1414414_+	hypothetical protein	NA	NA	NA	NA
WP_021143874.1\|1414693_1417786_+	hypothetical protein	NA	NA	NA	NA
WP_021147287.1\|1418089_1420330_+	hypothetical protein	NA	NA	NA	NA
WP_021147288.1\|1420596_1423458_+	hypothetical protein	NA	NA	NA	NA
WP_059749221.1\|1423843_1426369_+	glucosyl transferase	NA	NA	NA	NA
WP_059749223.1\|1426478_1427492_-	hypothetical protein	NA	NA	NA	NA
WP_059749225.1\|1427731_1430257_-	bifunctional lysylphosphatidylglycerol flippase/synthetase MprF	NA	NA	NA	NA
WP_021147294.1\|1430275_1431223_-	malate permease	NA	NA	NA	NA
WP_021147295.1\|1431306_1432932_-	NAD-dependent malic enzyme	NA	NA	NA	NA
WP_021147296.1\|1433106_1433457_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_021147297.1\|1433597_1434473_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002890057.1\|1434631_1435597_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	1.2e-45	45.0

DBSCAN-SWA_7

1615274 : 1625517

Streptococcus_phage(71.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014634864.1\|1615274_1617227_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	4.4e-143	45.4
WP_014634865.1\|1617227_1617788_-	HAD-IA family hydrolase	NA	NA	NA	NA
WP_002886784.1\|1617873_1618569_-	LrgB family protein	NA	NA	NA	NA
WP_002884266.1\|1618561_1618936_-	CidA/LrgA family protein	NA	NA	NA	NA
WP_021143768.1\|1619216_1619570_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	3.1e-39	65.8
WP_014634869.1\|1619604_1620099_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.5e-36	46.3
WP_021143767.1\|1620154_1621333_-	D-3-phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	5.1e-179	79.8
WP_021143766.1\|1621350_1621908_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	2.0e-56	59.6
WP_014634872.1\|1621920_1623015_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.6e-171	81.3
WP_021143765.1\|1623169_1624063_-	ROK family protein	NA	NA	NA	NA
WP_002884456.1\|1624178_1624574_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_004183097.1\|1624617_1625517_-	SPFH domain-containing protein	A0A1V0SL90	Klosneuvirus	1.8e-35	32.8

DBSCAN-SWA_8

2077173 : 2088598

Staphylococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021144751.1\|2077173_2077872_-	lytic transglycosylase domain-containing protein	Q4Z8Z7	Staphylococcus_phage	2.1e-26	70.7
WP_021144752.1\|2078055_2078628_-	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	1.7e-18	50.8
WP_021144753.1\|2078928_2079723_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_021144754.1\|2079715_2080558_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	6.3e-14	27.9
WP_021144755.1\|2080533_2081364_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	1.5e-20	32.3
WP_021144756.1\|2081376_2081919_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_048790842.1\|2081931_2082789_-	DUF4115 domain-containing protein	NA	NA	NA	NA
WP_021144759.1\|2082847_2084125_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	5.6e-06	28.6
WP_021144760.1\|2084126_2085377_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	2.3e-92	40.1
WP_021144761.1\|2085454_2085832_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	8.8e-24	71.1
WP_021144762.1\|2085834_2086935_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_021144763.1\|2087116_2088598_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.8e-95	40.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP013216

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection