CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022221	Salmonella enterica subsp. enterica serovar Gallinarum/pullorum str. CDC1983-67, complete genome	2 crisprs	DEDDh,cas3,DinG,WYL,csa3,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	0	1	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_022221_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022221_1

2931244-2931399

TypeI-E

I-E

Consensus_repeat	Method
AAACCGGTTTATCCCCGCTGGCGCGGGGAACACA	PILER-CR

2 spacers

cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NC_022221_1

>merge|NC_022221|1|2931244-2931399|PILER-CR
AAACGTGTTTATCCCCGCTGGCGCGGGGAACACGGCCGCTGGTCAAATTCCCAATCTGAGCAATCCGGTTTATCCCCGCTGGCGCGGGGAACACATAGCCCCGGCAGCGATAGCTAAACCAGTTCCCGGTTTATCCCCGCTGGCGCGGGGAACACA

>NC_022221|1|1|2931244-2931399|PILER-CR
AAACGTGTTTATCCCCGCTGGCGCGGGGAACACG	GCCGCTGGTCAAATTCCCAATCTGAGC
AATCCGGTTTATCCCCGCTGGCGCGGGGAACACA	TAGCCCCGGCAGCGATAGCTAAACCAG
TTCCCGGTTTATCCCCGCTGGCGCGGGGAACACA

Protein	Signature genes	Signature genes Name	Protein_function
NC_022221.1\|WP_000085115.1\|2933336_2934083_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NC_022221.1\|WP_000144830.1\|2931787_2932708_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NC_022221.1\|WP_000039871.1\|2941425_2942160_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NC_022221.1\|WP_001173665.1\|2926986_2927592_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NC_022221.1\|WP_000368579.1\|2935716_2937273_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NC_022221.1\|WP_000253545.1\|2922493_2923120_-\|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	unknown	unknown	gnl\|CDD\|178974
NC_022221.1\|WP_000029737.1\|2937284_2939948_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_022221.1\|WP_071524068.1\|2942086_2942305_+\|hypothetical-protein	unknown	unknown	unknown
NC_022221.1\|WP_000741653.1\|2925380_2926091_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NC_022221.1\|WP_001221538.1\|2923113_2923875_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NC_022221.1\|WP_001219253.1\|2924901_2925381_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NC_022221.1\|WP_000117945.1\|2935165_2935720_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NC_022221.1\|WP_001092251.1\|2927578_2929018_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NC_022221.1\|WP_000372384.1\|2929027_2929936_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NC_022221.1\|WP_001746886.1\|2940393_2941344_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NC_022221.1\|WP_000134251.1\|2923855_2924905_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NC_022221.1\|WP_020976772.1\|2932704_2933355_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NC_022221.1\|WP_000206417.1\|2934093_2935152_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NC_022221.1\|WP_000517480.1\|2926109_2926421_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NC_022221.1\|WP_020976771.1\|2930186_2931233_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299

Protein	Function_ID	Function_description	E-value
NC_022221.1\|WP_000085115.1\|2933336_2934083_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	5.23137e-48
NC_022221.1\|WP_000144830.1\|2931787_2932708_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.63116e-157
NC_022221.1\|WP_000039871.1\|2941425_2942160_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.31774e-138
NC_022221.1\|WP_001173665.1\|2926986_2927592_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	5.05843e-145
NC_022221.1\|WP_000368579.1\|2935716_2937273_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NC_022221.1\|WP_000253545.1\|2922493_2923120_-\|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	gnl\|CDD\|178974	PRK00312, pcm, protein-L-isoaspartate(D-aspartate) O-methyltransferase.	7.37904e-129
NC_022221.1\|WP_000029737.1\|2937284_2939948_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NC_022221.1\|WP_000741653.1\|2925380_2926091_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	4.09575e-119
NC_022221.1\|WP_001221538.1\|2923113_2923875_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.7078e-146
NC_022221.1\|WP_001219253.1\|2924901_2925381_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	3.84083e-103
NC_022221.1\|WP_000117945.1\|2935165_2935720_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.26497e-33
NC_022221.1\|WP_001092251.1\|2927578_2929018_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NC_022221.1\|WP_000372384.1\|2929027_2929936_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NC_022221.1\|WP_001746886.1\|2940393_2941344_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NC_022221.1\|WP_000134251.1\|2923855_2924905_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NC_022221.1\|WP_020976772.1\|2932704_2933355_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	5.34078e-74
NC_022221.1\|WP_000206417.1\|2934093_2935152_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.28543e-133
NC_022221.1\|WP_000517480.1\|2926109_2926421_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.08865e-64
NC_022221.1\|WP_020976771.1\|2930186_2931233_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0

>NC_022221.1|WP_020976771.1|2930186_2931233_+|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFFPGRMTDSPAEMLSADYLRQQFTQMGYQSDIRTFNSLFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGAGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>NC_022221.1|WP_000372384.1|2929027_2929936_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>NC_022221.1|WP_001092251.1|2927578_2929018_-|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYCEETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>NC_022221.1|WP_001173665.1|2926986_2927592_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRYGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>NC_022221.1|WP_000517480.1|2926109_2926421_-|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>NC_022221.1|WP_000741653.1|2925380_2926091_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLTISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>NC_022221.1|WP_001219253.1|2924901_2925381_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRISYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>NC_022221.1|WP_000134251.1|2923855_2924905_-|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFDGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQEAVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>NC_022221.1|WP_001221538.1|2923113_2923875_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
>NC_022221.1|WP_000253545.1|2922493_2923120_-|protein-L-isoaspartate(D-aspartate)-O-methyltransferase
MVSGRVQALLEQLRAQGIRDEQVLNALAAVPREKFIDEAFEHKAWENIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVHHVCSVERIKGLQWQARRRLKQLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMAQLDEGGILVLPVGDEQQFLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
>NC_022221.1|WP_000144830.1|2931787_2932708_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLNPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALDDDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRATYALLAKQYGVKWHGRNYDPKDWEKGDVVNRCISAATSCLYGISEAAILAAGYAPAIGFIHSGKPLSFVYDIADIIKFESVVPKAFEIAARHPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPESLGDSGHRGHG
>NC_022221.1|WP_020976772.1|2932704_2933355_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTSELSPAQLLHLVERGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQEQPAASTIFDVQTRPFAPMLSAGQTLRFNLRANPTICKNGKRHDLLMEAKRQRKTQGDSQDIWSYQQQAALGWLARQGEQNGFTLREASVDAYRQQQIRREKSRQMIQFSSVDYTGVLVINEPALFLQRLAQGYGKSWAFGCGMMMIKPGDDA
>NC_022221.1|WP_000085115.1|2933336_2934083_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNTFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGNAADVLREAYRWYQDQFNALKLTLPGLQNECWWEGEHDGLTANKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>NC_022221.1|WP_000206417.1|2934093_2935152_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITALHENMNEVYAQETAFKNFNVMNQQGSMKDVLDFICA
>NC_022221.1|WP_000117945.1|2935165_2935720_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHDELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDTDNEQD
>NC_022221.1|WP_000368579.1|2935716_2937273_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIRGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NC_022221.1|WP_000029737.1|2937284_2939948_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>NC_022221.1|WP_001746886.1|2940393_2941344_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILL
>NC_022221.1|WP_000039871.1|2941425_2942160_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLKTLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NC_022221.1|WP_071524068.1|2942086_2942305_+|hypothetical-protein
MVSANASTRSTFGSSFRAFRSSLDISSSRYTLPDGASLIRPTRAVGRIRHLCRHPAIQVIPRNHARDRAPGE

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Crispr_ID: NC_022221_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022221_2

2947545-2947937

TypeI-E

I-E

Consensus_repeat	Method
GTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
GTTTATCCCCGCTGGCGCGGGGAACAC	CRT
GTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

6 spacers

cas3,cas8e,cse2gr11

The CRISPR arrays of NC_022221_2

>merge|NC_022221|2|2947545-2947937|CRISPRCasFinder,CRT,PILER-CR
GGCTATCCTTGTTGGCGCGGGGAACACGGCTACACGCAAAAATTCCAGTCGTTGGCGCACGGTTTATCCCCGCTGGCGCGGGGAACACGTGGCCGGGTTGAGTACCGATCGCATTTTTTTCGGTTTATCCCCGCTGGCGCGGGGAACACTTCCCCTCCGGATGGCGGGGATGCTCTTATGGCGGTTTATCCCCGCTGGCGCGGGGAACACATCAAACATGGAAACCCCTTTAATGAGAGCAACGGTTTATCCCCGCTGGCGCGGGGAACACAATAATCGGCAATTTGTCCTGGACAGGCACGGCAGTTTATCCCCGCTGGCGCGGGGAACACGAATCTGGAGGCCAACAGCGCGGCGAAATCCTCAGTTTATCCCCGCTGGCGCGGGGAACAC

>NC_022221|2|1|2947545-2947937|CRISPRCasFinder
GGCTATCCTTGTTGGCGCGGGGAACAC	GGCTACACGCAAAAATTCCAGTCGTTGGCGCACG
GTTTATCCCCGCTGGCGCGGGGAACAC	GTGGCCGGGTTGAGTACCGATCGCATTTTTTTCG
GTTTATCCCCGCTGGCGCGGGGAACAC	TTCCCCTCCGGATGGCGGGGATGCTCTTATGGCG
GTTTATCCCCGCTGGCGCGGGGAACAC	ATCAAACATGGAAACCCCTTTAATGAGAGCAACG
GTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGGCA
GTTTATCCCCGCTGGCGCGGGGAACAC	GAATCTGGAGGCCAACAGCGCGGCGAAATCCTCA
GTTTATCCCCGCTGGCGCGGGGAACAC

>NC_022221|2|1|2947545-2947937|CRT
GGCTATCCTTGTTGGCGCGGGGAACAC	GGCTACACGCAAAAATTCCAGTCGTTGGCGCACG
GTTTATCCCCGCTGGCGCGGGGAACAC	GTGGCCGGGTTGAGTACCGATCGCATTTTTTTCG
GTTTATCCCCGCTGGCGCGGGGAACAC	TTCCCCTCCGGATGGCGGGGATGCTCTTATGGCG
GTTTATCCCCGCTGGCGCGGGGAACAC	ATCAAACATGGAAACCCCTTTAATGAGAGCAACG
GTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGGCA
GTTTATCCCCGCTGGCGCGGGGAACAC	GAATCTGGAGGCCAACAGCGCGGCGAAATCCTCA
GTTTATCCCCGCTGGCGCGGGGAACAC

>NC_022221|2|2|2947606-2947937|PILER-CR
GTTTATCCCCGCTGGCGCGGGGAACAC	GTGGCCGGGTTGAGTACCGATCGCATTTTTTTCG
GTTTATCCCCGCTGGCGCGGGGAACAC	TTCCCCTCCGGATGGCGGGGATGCTCTTATGGCG
GTTTATCCCCGCTGGCGCGGGGAACAC	ATCAAACATGGAAACCCCTTTAATGAGAGCAACG
GTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGGCA
GTTTATCCCCGCTGGCGCGGGGAACAC	GAATCTGGAGGCCAACAGCGCGGCGAAATCCTCA
GTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022221.1\|WP_000178269.1\|2957864_2958368_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185178
NC_022221.1\|WP_000210451.1\|2952286_2953087_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NC_022221.1\|WP_001199961.1\|2948233_2948905_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NC_022221.1\|WP_000210863.1\|2950421_2952059_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NC_022221.1\|WP_071524068.1\|2942086_2942305_+\|hypothetical-protein	unknown	unknown	unknown
NC_022221.1\|WP_000210929.1\|2943973_2945773_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NC_022221.1\|WP_000117945.1\|2935165_2935720_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NC_022221.1\|WP_000036734.1\|2949040_2950339_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NC_022221.1\|WP_000108313.1\|2946196_2946559_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NC_022221.1\|WP_001044462.1\|2957071_2957845_+\|fimbria/pilus-periplasmic-chaperone	unknown	unknown	gnl\|CDD\|185177
NC_022221.1\|WP_000368579.1\|2935716_2937273_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NC_022221.1\|WP_001072353.1\|2959440_2960472_+\|hypothetical-protein	unknown	unknown	unknown
NC_022221.1\|WP_001746886.1\|2940393_2941344_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NC_022221.1\|WP_000832393.1\|2958382_2958853_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185179
NC_022221.1\|WP_001079646.1\|2958849_2959386_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185168
NC_022221.1\|WP_001207998.1\|2946646_2947444_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158
NC_022221.1\|WP_001290671.1\|2942261_2943974_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NC_022221.1\|WP_000029737.1\|2937284_2939948_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_022221.1\|WP_000039871.1\|2941425_2942160_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NC_022221.1\|WP_000842510.1\|2953696_2954284_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185169

Protein	Function_ID	Function_description	E-value
NC_022221.1\|WP_000178269.1\|2957864_2958368_+\|fimbrial-protein	gnl\|CDD\|185178	PRK15275, PRK15275, putative fimbrial protein SteD; Provisional.	3.31433e-103
NC_022221.1\|WP_000210451.1\|2952286_2953087_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	3.42454e-158
NC_022221.1\|WP_001199961.1\|2948233_2948905_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.43874e-155
NC_022221.1\|WP_000210863.1\|2950421_2952059_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NC_022221.1\|WP_000210929.1\|2943973_2945773_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NC_022221.1\|WP_000117945.1\|2935165_2935720_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.26497e-33
NC_022221.1\|WP_000036734.1\|2949040_2950339_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NC_022221.1\|WP_000108313.1\|2946196_2946559_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
NC_022221.1\|WP_001044462.1\|2957071_2957845_+\|fimbria/pilus-periplasmic-chaperone	gnl\|CDD\|185177	PRK15274, PRK15274, putative periplasmic fimbrial chaperone protein SteC; Provisional.	0
NC_022221.1\|WP_000368579.1\|2935716_2937273_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NC_022221.1\|WP_001746886.1\|2940393_2941344_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NC_022221.1\|WP_000832393.1\|2958382_2958853_+\|fimbrial-protein	gnl\|CDD\|185179	PRK15276, PRK15276, putative fimbrial subunit SteE; Provisional.	2.10162e-98
NC_022221.1\|WP_001079646.1\|2958849_2959386_+\|fimbrial-protein	gnl\|CDD\|185168	PRK15260, PRK15260, fimbrial protein SteF; Provisional.	7.785e-121
NC_022221.1\|WP_001207998.1\|2946646_2947444_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	1.00381e-102
NC_022221.1\|WP_001290671.1\|2942261_2943974_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NC_022221.1\|WP_000029737.1\|2937284_2939948_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NC_022221.1\|WP_000039871.1\|2941425_2942160_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.31774e-138
NC_022221.1\|WP_000842510.1\|2953696_2954284_+\|fimbrial-protein	gnl\|CDD\|185169	PRK15261, PRK15261, fimbrial protein SteA; Provisional.	1.73148e-99

>NC_022221.1|WP_001207998.1|2946646_2947444_-|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNALAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRDPLPIGKNFIWSGEIPVVAPEAYGIFGGHDAEPDSILDEGVLIYQSTKGLVIITGCGHRGIANIVRHCQNITGIKRIYALVGGFHLRCASPFTLWRVRRFLQEQKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>NC_022221.1|WP_000108313.1|2946196_2946559_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>NC_022221.1|WP_000210929.1|2943973_2945773_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGVVAVTPVPERKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLIATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAEALIGLLRPLTPRLYSIASAQAEVESEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRAFMQQRAADGAEGKNLLFFGNPHFTEDFLYQVEWQRYVKEGVLSRIALAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARSMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>NC_022221.1|WP_001290671.1|2942261_2943974_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPLMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NC_022221.1|WP_071524068.1|2942086_2942305_+|hypothetical-protein
MVSANASTRSTFGSSFRAFRSSLDISSSRYTLPDGASLIRPTRAVGRIRHLCRHPAIQVIPRNHARDRAPGE
>NC_022221.1|WP_000039871.1|2941425_2942160_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLKTLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NC_022221.1|WP_001746886.1|2940393_2941344_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILL
>NC_022221.1|WP_000029737.1|2937284_2939948_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>NC_022221.1|WP_000368579.1|2935716_2937273_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIRGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NC_022221.1|WP_000117945.1|2935165_2935720_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHDELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDTDNEQD
>NC_022221.1|WP_001199961.1|2948233_2948905_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMPLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>NC_022221.1|WP_000036734.1|2949040_2950339_-|phosphopyruvate-hydratase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NC_022221.1|WP_000210863.1|2950421_2952059_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
>NC_022221.1|WP_000210451.1|2952286_2953087_-|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>NC_022221.1|WP_000842510.1|2953696_2954284_+|fimbrial-protein
MKSSHFCKLAVTASLVMGIVSGAQAAGSNTAKVTFLGNIVDSPCSVTLDTEDQTVNMGSSIGNGTLSNGKTTINNARTFHIDLEGCTWATEKNMNVVFTTGSGTTAATDATDNLALMKTDGTGAISNVSLAIGDAGKNNIKLGDTYTQAIADLDGDTILDEKQSLNFTAWLVGAATGTVGTGEFSSAANVTISYL
>NC_022221.1|WP_001044462.1|2957071_2957845_+|fimbria/pilus-periplasmic-chaperone
MNKTNHFKRQALIASVLLAAPLVSHSAIVPDRTRVIFNGNENSITVTLKNGNATLPYLAQAWLEDDKFAKDTRYFTALPPLQRIEPKSDGQVKVQPLPTAASLPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAVARQVDKTHPWQTKLTLTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTSPIKGASLGSSPVVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK
>NC_022221.1|WP_000178269.1|2957864_2958368_+|fimbrial-protein
MTMLTRWKMLVLLCGGFVTGTEAAGTKTVQLELHLVVTQPPPCTVGGASVEFGDVLTTKVGDASQTKPVGYSLNCDGRASDYLKLQIQGTTTISGEQVLQTSVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNASATLVVDYQ
>NC_022221.1|WP_000832393.1|2958382_2958853_+|fimbrial-protein
MKRVLILTLLITQFACADNLTFHGKLINPPACTINNGEMLEVSFGSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSAKALTTSVPELGIELQQNGTVFPPGTSLTINESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ
>NC_022221.1|WP_001079646.1|2958849_2959386_+|fimbrial-protein
MNRIFQTAGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNLVVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVLVTFQGVEDSTLPGLLALEPSSEASGFAIGVETAAQQPVSINATVGTAFVLKEGITTINLQARLQKYAGEEVMPGEFSGSATVSFEYQ
>NC_022221.1|WP_001072353.1|2959440_2960472_+|hypothetical-protein
MNQKVLFFLSIIAYPGITQAINQNVMIEPLVIRDSTNYLVLPQAQQAEFSQCKSWPHDSTVIPAKYEATLLNGSLISMFIGGITVNLYTTADVKVNTDAQCTLLNGNFPGYYGITCFVTGYDTDKAVPVRTDNGMSIIESKLYATGTMRYITEIPMDGSGFQGMAIGGAVVINTGAITPTPNTGVISNITMPPLYDPGFIFTVPGCGQYKYHSGTGSVFTNNNSTYTVASPIGFITASLDKNSVLNYNELHYNDKAENIELGKIYLMYKEKNVTWGEGFDYTLENSTINVVCADSRIKTNVDYQCRNGDMGACNNGELGRIIGNWERINVDTNCSVTVILPWQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_022221_1	1.1\|2931278\|27\|NC_022221\|PILER-CR	2931278-2931304	27	MK449011	Streptococcus phage Javan92, complete genome	36161-36187	5	0.815
NC_022221_1	1.1\|2931278\|27\|NC_022221\|PILER-CR	2931278-2931304	27	MK448835	Streptococcus phage Javan93, complete genome	36161-36187	5	0.815
NC_022221_1	1.1\|2931278\|27\|NC_022221\|PILER-CR	2931278-2931304	27	MK448836	Streptococcus phage Javan95, complete genome	37404-37430	5	0.815
NC_022221_1	1.1\|2931278\|27\|NC_022221\|PILER-CR	2931278-2931304	27	MK448825	Streptococcus phage Javan639, complete genome	37404-37430	5	0.815

1. spacer 1.1|2931278|27|NC_022221|PILER-CR matches to MK449011 (Streptococcus phage Javan92, complete genome) position: , mismatch: 5, identity: 0.815

gccgctggtcaaattcccaatctgagc	CRISPR spacer
acatcttgacaaattcccaatctgagc	Protospacer
.*  ** * ******************

2. spacer 1.1|2931278|27|NC_022221|PILER-CR matches to MK448835 (Streptococcus phage Javan93, complete genome) position: , mismatch: 5, identity: 0.815

gccgctggtcaaattcccaatctgagc	CRISPR spacer
acatcttgacaaattcccaatctgagc	Protospacer
.*  ** * ******************

3. spacer 1.1|2931278|27|NC_022221|PILER-CR matches to MK448836 (Streptococcus phage Javan95, complete genome) position: , mismatch: 5, identity: 0.815

gccgctggtcaaattcccaatctgagc	CRISPR spacer
acatcttgacaaattcccaatctgagc	Protospacer
.*  ** * ******************

4. spacer 1.1|2931278|27|NC_022221|PILER-CR matches to MK448825 (Streptococcus phage Javan639, complete genome) position: , mismatch: 5, identity: 0.815

gccgctggtcaaattcccaatctgagc	CRISPR spacer
acatcttgacaaattcccaatctgagc	Protospacer
.*  ** * ******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

781068 : 790239

Enterobacteria_phage(66.67%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569175.1\|781068_782016_+	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	1.6e-10	27.8
WP_000824854.1\|781999_782731_+	ABC transporter permease	NA	NA	NA	NA
WP_001747411.1\|782711_782819_-	protein YohO	NA	NA	NA	NA
WP_001240413.1\|782878_783610_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	1.3e-100	87.9
WP_000272844.1\|783832_785518_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	2.4e-278	90.9
WP_000598636.1\|785514_786234_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_000950414.1\|786280_786748_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	4.3e-73	89.7
WP_001197951.1\|786804_787335_-	YehR family lipoprotein	NA	NA	NA	NA
WP_000703145.1\|787506_787965_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	6.4e-53	72.5
WP_000195354.1\|788205_790239_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	1.0e-54	26.9

DBSCAN-SWA_2

857432 : 867939

Enterobacteria_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001144951.1\|857432_858836_+	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	4.0e-21	26.5
WP_000981469.1\|859013_859907_+	GalU regulator GalF	A0A127AW70	Bacillus_phage	4.8e-44	42.2
WP_000697846.1\|860283_861369_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.6e-102	53.9
WP_001023658.1\|861368_862268_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	5.1e-30	36.0
WP_000857535.1\|862315_863194_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.1e-108	65.5
WP_000973709.1\|863194_863746_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.3e-52	58.0
WP_000018223.1\|863751_864726_+	CDP-6-deoxy-delta-3,4-glucoseen reductase	NA	NA	NA	NA
WP_000648783.1\|864741_865515_+	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_000565913.1\|865519_866599_+	CDP-glucose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	1.7e-16	24.5
WP_000126349.1\|866625_867939_+	lipopolysaccharide biosynthesis protein RfbH	H8ZJ36	Ostreococcus_tauri_virus	7.0e-52	35.1

DBSCAN-SWA_3

1663965 : 1754262

Enterobacteria_phage(27.66%)

lysis,integrase,terminase,tail,tRNA,portal,protease,holin

attL 1730640:1730654|attR 1756031:1756045

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001221017.1\|1663965_1664661_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_000128810.1\|1664718_1666629_-	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	8.5e-91	32.4
WP_000029550.1\|1666759_1667104_+	RidA family protein	NA	NA	NA	NA
WP_000457328.1\|1667109_1667289_-	YoaH family protein	NA	NA	NA	NA
WP_000978451.1\|1667369_1668734_+	aminodeoxychorismate synthase component 1	A0A0B5J984	Pandoravirus	3.6e-43	34.5
WP_000381544.1\|1668737_1669316_+	CoA pyrophosphatase	NA	NA	NA	NA
WP_000624273.1\|1669579_1670944_+	L-serine ammonia-lyase	NA	NA	NA	NA
WP_001192535.1\|1671081_1672683_+	cyclic diguanylate phosphodiesterase	NA	NA	NA	NA
WP_000421815.1\|1672704_1674264_-	CNNM family cation transport protein YoaE	A0A0R6PEZ3	Moraxella_phage	9.5e-40	44.4
WP_000150523.1\|1674736_1675705_+	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_000406920.1\|1675757_1676558_+	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_001518647.1\|1676570_1677422_+	PTS mannose transporter subunit IID	NA	NA	NA	NA
WP_001518359.1\|1678348_1678915_+	manganese efflux pump MntP	NA	NA	NA	NA
WP_000010915.1\|1678911_1679721_-	23S rRNA (guanine(745)-N(1))-methyltransferase	NA	NA	NA	NA
WP_000730310.1\|1679786_1681532_-	peptidoglycan glycosyltransferase FtsI	NA	NA	NA	NA
WP_001062678.1\|1681751_1681961_-	transcription antiterminator/RNA stability regulator CspE	A0A1W6JNX5	Morganella_phage	1.6e-22	78.1
WP_001537930.1\|1681973_1682117_-	YobF family protein	NA	NA	NA	NA
WP_000714548.1\|1683122_1683266_-	PhoP/PhoQ regulator MgrB	NA	NA	NA	NA
WP_001236777.1\|1683423_1683663_+	hypothetical protein	NA	NA	NA	NA
WP_001262195.1\|1683874_1684666_-	DNA-binding transcriptional regulator KdgR	NA	NA	NA	NA
WP_001747327.1\|1684841_1686215_+	MFS transporter	NA	NA	NA	NA
WP_000984498.1\|1686262_1687144_-\|protease	protease HtpX	NA	NA	NA	NA
WP_001091237.1\|1687336_1689385_-	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	8.0e-87	33.5
WP_000431401.1\|1689404_1690091_-	RNA chaperone ProQ	NA	NA	NA	NA
WP_000145732.1\|1690188_1690773_-	GAF domain-containing protein	NA	NA	NA	NA
WP_001207294.1\|1690814_1692098_+	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
WP_077909763.1\|1692060_1694700_+	PqiB family protein	NA	NA	NA	NA
WP_023164993.1\|1694777_1696217_+	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
WP_000978525.1\|1696331_1696571_+	DUF1480 family protein	NA	NA	NA	NA
WP_000457838.1\|1696681_1696873_+	YebW family protein	NA	NA	NA	NA
WP_000986172.1\|1696891_1697542_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	5.5e-58	50.9
WP_001134856.1\|1697765_1697930_-	membrane protein	NA	NA	NA	NA
WP_000182072.1\|1698215_1698938_-	SPI-1 type III secretion system guanine nucleotide exchange factor SopE2	NA	NA	NA	NA
WP_000422882.1\|1699621_1700017_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	9.2e-16	32.8
WP_000030934.1\|1700346_1700823_+	hypothetical protein	NA	NA	NA	NA
WP_001025514.1\|1701195_1701615_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001532329.1\|1701746_1701941_-	hypothetical protein	NA	NA	NA	NA
WP_001576019.1\|1701987_1702257_+	hypothetical protein	B6SCX2	Bacteriophage	3.1e-07	47.9
WP_001576018.1\|1702422_1702563_+	hypothetical protein	NA	NA	NA	NA
WP_001674911.1\|1704884_1705085_-	hypothetical protein	NA	NA	NA	NA
WP_001233445.1\|1705702_1706617_+	DMT family transporter	NA	NA	NA	NA
WP_000480735.1\|1706749_1706908_+	hypothetical protein	NA	NA	NA	NA
WP_000848072.1\|1706917_1707532_+	disulfide bond formation protein B	NA	NA	NA	NA
WP_001668484.1\|1708284_1708551_-	hypothetical protein	NA	NA	NA	NA
WP_000457876.1\|1708679_1708805_-	hypothetical protein	NA	NA	NA	NA
WP_001525008.1\|1709067_1709184_+	hypothetical protein	NA	NA	NA	NA
WP_001576015.1\|1709374_1709575_+	hypothetical protein	NA	NA	NA	NA
WP_000178848.1\|1712698_1712941_-	hypothetical protein	NA	NA	NA	NA
WP_072100756.1\|1712979_1713843_-	DUF1983 domain-containing protein	K7PKJ2	Enterobacteria_phage	9.0e-48	78.9
WP_149022580.1\|1713838_1716331_-	host specificity protein J	A0A0P0ZEQ8	Stx2-converting_phage	0.0e+00	67.5
WP_001576012.1\|1716402_1717107_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.4e-67	63.1
WP_000606352.1\|1717010_1717742_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	1.0e-113	75.6
WP_001152416.1\|1717751_1718447_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.0e-89	66.7
WP_000877926.1\|1718536_1719070_+	superoxide dismutase [Cu-Zn]	Q9MC02	Salmonella_phage	1.8e-46	54.0
WP_000725267.1\|1719186_1719684_-	outer membrane beta-barrel protein	A0A1B0VBR9	Salmonella_phage	1.4e-16	36.6
WP_000978295.1\|1719782_1720115_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	2.6e-35	61.5
WP_077904894.1\|1720111_1723099_-\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	1.1e-265	62.0
WP_010989009.1\|1723178_1723508_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	5.0e-23	50.9
WP_000478857.1\|1723504_1723903_-\|tail	phage minor tail protein G	K7PLV8	Enterobacteria_phage	8.6e-30	56.8
WP_000132760.1\|1723948_1724698_-\|tail	phage tail protein	A0A291AWU6	Escherichia_phage	3.1e-89	68.2
WP_000196704.1\|1724709_1725111_-\|tail	phage tail protein U	K7PHM6	Enterobacterial_phage	3.8e-41	59.4
WP_000453192.1\|1725107_1725674_-\|tail	phage tail protein	Q9G063	Phage_Gifsy-2	2.1e-13	95.7
WP_000774239.1\|1725654_1725954_-	ATP-binding protein	K7PH43	Enterobacteria_phage	4.5e-15	45.1
WP_001107908.1\|1725946_1726270_-	DUF2190 family protein	K7PLV6	Enterobacteria_phage	7.7e-29	61.3
WP_010989008.1\|1726360_1728442_-\|protease	Clp protease ClpP	A0A291AWT6	Escherichia_phage	4.8e-265	69.5
WP_077909778.1\|1728365_1729883_-\|portal	phage portal protein	A0A291AWU2	Escherichia_phage	7.1e-173	64.5
WP_000196190.1\|1729909_1730116_-	hypothetical protein	A0A1W6JT66	Pseudomonas_phage	2.9e-05	53.3
WP_000989241.1\|1730112_1732251_-\|terminase	phage terminase large subunit family protein	A5LH27	Enterobacteria_phage	3.4e-290	72.6
1730640:1730654	attL	NA	NA	NA	NA
WP_000371784.1\|1732207_1732741_-	DUF1441 family protein	A0A291AWV8	Escherichia_phage	1.0e-33	48.1
WP_001541990.1\|1732948_1733428_-\|lysis	lysis protein	Q56118	Enterobacteria_phage	1.4e-55	77.0
WP_000984586.1\|1733445_1733898_-	lysozyme	A0A0M4R365	Salmonella_phage	2.3e-79	97.3
WP_001574216.1\|1733881_1734211_-\|holin	phage holin, lambda family	A0A0M3ULK9	Salmonella_phage	5.8e-56	100.0
WP_001574215.1\|1734486_1735173_+	PipA/GogA/GtgA family type III secretion system effector	Q9MBM0	Phage_Gifsy-2	1.8e-131	99.6
WP_000798708.1\|1735533_1735983_+	hypothetical protein	NA	NA	NA	NA
WP_001574213.1\|1736356_1736881_-	hypothetical protein	NA	NA	NA	NA
WP_001097218.1\|1736977_1737667_-	antitermination protein	I6PDF8	Cronobacter_phage	2.1e-60	54.9
WP_000784710.1\|1737796_1738024_-	DNA breaking-rejoining protein	A0A0M4RU10	Salmonella_phage	2.2e-14	66.7
WP_000940753.1\|1738020_1738620_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	4.7e-96	82.9
WP_000972672.1\|1738683_1738989_-	hypothetical protein	NA	NA	NA	NA
WP_001676972.1\|1739411_1739603_+	hypothetical protein	NA	NA	NA	NA
WP_024143656.1\|1739620_1741600_-	MBL fold metallo-hydrolase	A0A2P0VMX1	Tetraselmis_virus	2.5e-162	46.3
WP_000529511.1\|1741996_1743127_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_000089416.1\|1743413_1743809_-	DUF977 family protein	A0A088CBK9	Shigella_phage	9.8e-18	38.8
WP_000140162.1\|1743821_1744283_-	hypothetical protein	A0A0U2JGJ0	Escherichia_phage	3.5e-67	75.5
WP_000729536.1\|1744275_1745274_-	DUF1376 domain-containing protein	A0A0U2RT81	Escherichia_phage	4.1e-121	67.3
WP_001574210.1\|1745320_1745815_-	hypothetical protein	NA	NA	NA	NA
WP_001033912.1\|1745801_1746056_-	helix-turn-helix transcriptional regulator	K7PKH4	Enterobacteria_phage	5.3e-17	60.9
WP_001574209.1\|1746154_1746553_+	helix-turn-helix domain-containing protein	K7PH19	Enterobacteria_phage	1.2e-18	56.0
WP_000687579.1\|1746955_1747222_+	hypothetical protein	NA	NA	NA	NA
WP_000103933.1\|1747559_1747835_+	hypothetical protein	NA	NA	NA	NA
WP_000682660.1\|1747838_1748045_+	cell division inhibitor protein	I6PBM9	Cronobacter_phage	3.0e-10	45.6
WP_000799627.1\|1748120_1748456_+	hypothetical protein	NA	NA	NA	NA
WP_000023717.1\|1748596_1751287_+	exodeoxyribonuclease VIII	Q9QF34	Lambdoid_phage	4.0e-118	72.8
WP_001126031.1\|1751279_1752110_+	recombination protein RecT	A0A1P8DTF2	Proteus_phage	1.3e-104	72.0
WP_000280163.1\|1752156_1752342_+	DUF1187 family protein	NA	NA	NA	NA
WP_001574207.1\|1752632_1752869_+	hypothetical protein	NA	NA	NA	NA
WP_001575998.1\|1752929_1753208_+	excisionase	A0A2H4J5E1	uncultured_Caudovirales_phage	1.4e-10	37.5
WP_000087636.1\|1753182_1754262_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	3.0e-101	52.5
1756031:1756045	attR	NA	NA	NA	NA

DBSCAN-SWA_4

2057129 : 2064442

Ralstonia_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001746929.1\|2057129_2057507_+	hypothetical protein	A0A077KET4	Ralstonia_phage	1.2e-20	41.0
WP_001117984.1\|2057668_2057866_+	hypothetical protein	NA	NA	NA	NA
WP_000934060.1\|2058078_2060355_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	4.0e-164	42.1
WP_000520789.1\|2060385_2060706_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	4.5e-13	45.7
WP_000447499.1\|2061029_2061251_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	9.3e-18	64.2
WP_000125872.1\|2061380_2063327_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	2.0e-39	43.1
WP_001201751.1\|2063323_2064442_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.4e-08	38.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022221

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection