CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022234	Variovorax paradoxus B4 chromosome 2, complete sequence	0 crisprs	RT,csa3,Cas9_archaeal,PD-DExK,PrimPol	0	0	0	0
NC_022247	Variovorax paradoxus B4 chromosome 1, complete sequence	2 crisprs	RT,DEDDh,WYL,csa3,DinG,cas3	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_022247_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022247_1

408692-408830

Orphan

Consensus_repeat	Method
CACCGCGGAACCGGCTTTGCCGGGCCGCTGGTGTTGCCCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022247_1

>merge|NC_022247|1|408692-408830|CRISPRCasFinder
CACCGCGGAACCGGCTTTGCCGGGCCGCTGGTGTTGCCCCCGGTAGGGGGTTGGCGAAGCGACACGAAGTGCGCGAAGACTGGGGGCGAGCCAAGTGCCACCGCGGAACCGGCTTTGCCGGGCCGCTGGTGTTGCCCCC

>NC_022247|1|1|408692-408830|CRISPRCasFinder
CACCGCGGAACCGGCTTTGCCGGGCCGCTGGTGTTGCCCCC	GGTAGGGGGTTGGCGAAGCGACACGAAGTGCGCGAAGACTGGGGGCGAGCCAAGTGC
CACCGCGGAACCGGCTTTGCCGGGCCGCTGGTGTTGCCCCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022247.1\|WP_021005081.1\|412353_413625_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|236722
NC_022247.1\|WP_021005078.1\|411085_411499_-\|RNA-binding-protein	unknown	unknown	gnl\|CDD\|240845
NC_022247.1\|WP_021005084.1\|415686_416847_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173847
NC_022247.1\|WP_021005071.1\|402878_404120_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|235596
NC_022247.1\|WP_021005075.1\|407308_408655_+\|chromate-efflux-transporter	unknown	unknown	gnl\|CDD\|273350
NC_022247.1\|WP_021005080.1\|411919_412294_-\|translation-initiation-factor-Sui1	unknown	unknown	gnl\|CDD\|168689
NC_022247.1\|WP_021005069.1\|400340_401879_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143448
NC_022247.1\|WP_021005070.1\|401976_402882_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270406
NC_022247.1\|WP_021005066.1\|397190_398042_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224097
NC_022247.1\|WP_021005072.1\|404139_405813_+\|thiamine-pyrophosphate-binding-protein	unknown	unknown	gnl\|CDD\|181285
NC_022247.1\|WP_021005077.1\|410402_410891_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	unknown	unknown	gnl\|CDD\|377815
NC_022247.1\|WP_021005083.1\|414517_415681_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173849
NC_022247.1\|WP_021005074.1\|406527_407286_+\|TSUP-family-transporter	unknown	unknown	gnl\|CDD\|182593
NC_022247.1\|WP_021005085.1\|416861_417776_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187627
NC_022247.1\|WP_021005076.1\|408877_410389_-\|tripartite-tricarboxylate-transporter-permease	unknown	unknown	gnl\|CDD\|225870
NC_022247.1\|WP_021005079.1\|411679_411913_-\|DUF3820-family-protein	unknown	unknown	gnl\|CDD\|378970
NC_022247.1\|WP_021005082.1\|413666_414419_-\|slipin-family-protein	unknown	unknown	gnl\|CDD\|259808
NC_022247.1\|WP_021005067.1\|398038_399109_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NC_022247.1\|WP_021005068.1\|399312_400173_+\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NC_022247.1\|WP_051255292.1\|405819_406131_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_022247.1\|WP_021005081.1\|412353_413625_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|236722	PRK10590, PRK10590, ATP-dependent RNA helicase RhlE; Provisional.	5.66299e-144
NC_022247.1\|WP_021005078.1\|411085_411499_-\|RNA-binding-protein	gnl\|CDD\|240845	cd12399, RRM_HP0827_like, RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins. This subfamily corresponds to the RRM of H. pylori HP0827, a putative ssDNA-binding protein 12rnp2 precursor, containing one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain). The ssDNA binding may be important in activation of HP0827. .	6.48519e-35
NC_022247.1\|WP_021005084.1\|415686_416847_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	6.93515e-111
NC_022247.1\|WP_021005071.1\|402878_404120_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
NC_022247.1\|WP_021005075.1\|407308_408655_+\|chromate-efflux-transporter	gnl\|CDD\|273350	TIGR00937, Chromate_transport_protein, chromate transporter, chromate ion transporter (CHR) family. Members of this family probably act as chromate transporters, and are found in Pseudomonas aeruginosa, Alcaligenes eutrophus, Vibrio cholerae, Bacillus subtilis, Ochrobactrum tritici, cyanobacteria and archaea. The protein reduces chromate accumulation and is essential for chromate resistance. [Transport and binding proteins, Anions].	3.83947e-60
NC_022247.1\|WP_021005080.1\|411919_412294_-\|translation-initiation-factor-Sui1	gnl\|CDD\|168689	PRK06824, PRK06824, translation initiation factor Sui1; Validated.	1.55196e-50
NC_022247.1\|WP_021005069.1\|400340_401879_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143448	cd07130, ALDH_F7_AASADH, NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B. Alpha-aminoadipic semialdehyde dehydrogenase (AASADH, EC=1.2.1.31), also known as ALDH7A1, Antiquitin-1, ALDH7B, or delta-1-piperideine-6-carboxylate dehydrogenase (P6CDH), is a NAD+-dependent ALDH. Human ALDH7A1 is involved in the pipecolic acid pathway of lysine catabolism, catalyzing the oxidation of alpha-aminoadipic semialdehyde to alpha-aminoadipate. Arabidopsis thaliana ALDH7B4 appears to be an osmotic-stress-inducible ALDH gene encoding a turgor-responsive or stress-inducible ALDH. The Streptomyces clavuligerus P6CDH appears to be involved in cephamycin biosynthesis, catalyzing the second stage of the two-step conversion of lysine to alpha-aminoadipic acid. The ALDH7A1 enzyme and others in this group have been observed as tetramers, yet the bacterial P6CDH enzyme has been reported as a monomer.	0
NC_022247.1\|WP_021005070.1\|401976_402882_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270406	cd13688, PBP2_GltI_DEBP, Substrate-binding domain of ABC aspartate-glutamate transporter; the type 2 periplasmic binding protein fold. This subfamily represents the periplasmic-binding protein component of ABC transporter specific for carboxylic amino acids, including GtlI from Escherichia coli. The aspartate-glutamate binding domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.15576e-82
NC_022247.1\|WP_021005066.1\|397190_398042_-\|ABC-transporter-permease	gnl\|CDD\|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	3.20471e-75
NC_022247.1\|WP_021005072.1\|404139_405813_+\|thiamine-pyrophosphate-binding-protein	gnl\|CDD\|181285	PRK08199, PRK08199, thiamine pyrophosphate protein; Validated.	0
NC_022247.1\|WP_021005077.1\|410402_410891_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	gnl\|CDD\|377815	pfam07331, TctB, Tripartite tricarboxylate transporter TctB family. This family consists of several hypothetical bacterial proteins of around 150 residues in length. This family was formerly known as DUF1468.	0.001717
NC_022247.1\|WP_021005083.1\|414517_415681_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173849	cd01160, LCAD, Long chain acyl-CoA dehydrogenase. LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer.	2.13858e-137
NC_022247.1\|WP_021005074.1\|406527_407286_+\|TSUP-family-transporter	gnl\|CDD\|182593	PRK10621, PRK10621, hypothetical protein; Provisional.	1.72343e-47
NC_022247.1\|WP_021005085.1\|416861_417776_-\|SDR-family-oxidoreductase	gnl\|CDD\|187627	cd05369, TER_DECR_SDR_a, Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR. TTER is a peroxisomal protein with a proposed role in fatty acid elongation. Fatty acid synthesis is known to occur in the both endoplasmic reticulum and mitochondria; peroxisomal TER has been proposed as an additional fatty acid elongation system, it reduces the double bond at C-2 as the last step of elongation. This system resembles the mitochondrial system in that acetyl-CoA is used as a carbon donor. TER may also function in phytol metabolism, reducting phytenoyl-CoA to phytanoyl-CoA in peroxisomes. DECR processes double bonds in fatty acids to increase their utility in fatty acid metabolism; it reduces 2,4-dienoyl-CoA to an enoyl-CoA. DECR is active in mitochondria and peroxisomes. This subgroup has the Gly-rich NAD-binding motif of the classical SDR family, but does not display strong identity to the canonical active site tetrad, and lacks the characteristic Tyr at the usual position. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	3.77023e-88
NC_022247.1\|WP_021005076.1\|408877_410389_-\|tripartite-tricarboxylate-transporter-permease	gnl\|CDD\|225870	COG3333, COG3333, Uncharacterized protein conserved in bacteria [Function unknown].	0
NC_022247.1\|WP_021005079.1\|411679_411913_-\|DUF3820-family-protein	gnl\|CDD\|378970	pfam12843, QSregVF_b, Putative quorum-sensing-regulated virulence factor. QSregVF_b is a family of short Pseudomonas proteins that are potential virulence factors. The structure of UniProtKB:Q9HY15 a secreted protein has been solved and deposited as Structure 3npd, from pfam13652. It is predicted that these two adjacent proteins form a single transcriptional unit based on the prediction that together they interact with their adjacent protein PotD, which is the putrescine-binding periplasmic protein in the polyamine uptake system comprising PotABCD. These two adjacent proteins are predicted to be quroum-sensing-regulated virulence factors.	2.32305e-37
NC_022247.1\|WP_021005082.1\|413666_414419_-\|slipin-family-protein	gnl\|CDD\|259808	cd08826, SPFH_eoslipins_u1, Uncharacterized prokaryotic subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes a subgroup of the stomatin-like protein family (SLPs or slipins) that is found in bacteria and archaebacteria. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Bacterial and archaebacterial SLPs remain uncharacterized. This subgroup contains PH1511 from the hyperthermophilic archaeon Pyrococcus horikoshi.	3.55377e-102
NC_022247.1\|WP_021005067.1\|398038_399109_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.14259e-151
NC_022247.1\|WP_021005068.1\|399312_400173_+\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	6.86256e-49

>NC_022247.1|WP_021005075.1|407308_408655_+|chromate-efflux-transporter
MRPPEPVEPPAPVSFWQAFAYWLKLGFISFGGPAGQIALMHQELVERRRWISEKRFLHALNYCMLLPGPEAQQLATYIGWLMHRTWGGIAAGVLFVLPSLFILIGLSWAYMAYGQVPAVAGLLYGVKPAVTAIVLFAAWRIGSRVLKNAWLWAIAVAAFVAIFALRLPFPLIVLSAGAIGYFGSRFAPAYFAPGGGHGAAAASAGPALIDDDTPTPAHARFGWGRFARVLAVFLLLWLGALGTLAALYGWNGALAQMGWFFTKAALLTFGGAYAVLPYVFQGAVDHYHWLSATQMIDGLALGETTPGPLIMVVSFVGFVGGWGQALFGPQALFAAGAAAAAVVTFFTFLPSFLFILLGGPFIESTHGNLKFTAPLTAITAAVVGVIVNLAVFFAYHVLWPAGLSGRFEIPSALIGAIAAIALFRFKAGVIPVVLGSALAGMAWQLLVR
>NC_022247.1|WP_021005074.1|406527_407286_+|TSUP-family-transporter
MEMLVVTGASLLAGFVDSIVGGGGLILVPALFAVFPGAPPATLLGTNKSASIWGTAAAAAQFSQRVQMRWGALWPAALLGFMGSMLGAWGVTVFPGDFLRRALPVVLLGVLLYTLARKDLGRNHVPRFSGRAETLAACAIGLSIGFYDGFFGPGAGSFLVFLFVRWMGYDFLNASASAKIINTLTNAAALLLLALKGHVWWHYGLVMAVANVAGSLLGTRVALKHGAGFVRVVFIVVVSALILKTAYDAFLK
>NC_022247.1|WP_051255292.1|405819_406131_-|hypothetical-protein
METVMSMSESERIALAARLHVALRRKHGRVTDTEWMATNAEYAAEIVRMTRAHAVETKDEDLYLLATRLEQAMEPLARAARLAARTPDGNSPNPLPRYADGLR
>NC_022247.1|WP_021005072.1|404139_405813_+|thiamine-pyrophosphate-binding-protein
MTSSRTGGQILVDQLITHGVKQLFCVPGESFLAVLDALHDASIDVTVCRQEGGATMMAEAQGKLTGKPGVCFVTRGPGATNAAAGVHIAHQDSTPLLLFVGQVAREALGREAFQELDYGAVFGTMAKWVVQIDDPARVPELVSRAFHVATSGRPGPVVIALPEDMLTEAATVADAQPCAVVETHPGAAQIAELQQRLSQAERPVVILGGSRWSEAATQQFAAFAEAFSLPVYCSFRRQMLLSAEHPCYAGDLGLGANPRMLERIRNADLVLLVGGRLSEVPSQGYELLAIPQPKQALVHVHADADELGKLYRPTQGIHATPQAFAEAVSALRPASPPVWQAETKAAREDFLRWSDPAPIRIPGPLQMGEVMQHLREVLPADTIFCNGAGNFATWVHRFWPFRAFASQLAPTSGSMGYGLPAGVGAKRLWPQREVVVFAGDGDFMMHGQEFATAVQYGLPILVVLLDNAMYGTIRMHQEKHYPGRVSATQLRNPDFRGYAEVFGGHGERVASTAEFGPALARARASGKPAILHCLLDPEAITPGSTLQSIRKAALAAG
>NC_022247.1|WP_021005071.1|402878_404120_+|pyridoxal-phosphate-dependent-aminotransferase
MTSAVLDPALSTSAFEPAQRVRAIGVSEILRITDHANALKRAGRPVIVLGAGEPDFDTPEHIRAAAARAMERGDTRYTVLDGSPAMKAAVQLKFRRDNALDFALDEISVGAGAKQVIFNALMASLDPGDEVILPAPYWTSYADIVQICGGVPVSVPCSEANGFRLDAAQLESAITPRTRWLFLNSPSNPSGAAYSAAQLAPLCEVLLRHPSVWVLADDIYEHILYDGLAFATPAAVEPRLRDRTLTVNGVSKAYAMTGWRVGYGAGPRALIAAMAVVQSQSTSCPSSVSQAAAIEALTGPQDIVAERRDDFQARRDFVVAALNRAPGLHCRMPEGAFYTFASCAGLLGRRTRGGTLLQTDSDFCSYLLQDYEVAVVPGSVFGLAPYFRISYATSMAQLEEACARIASACEALT
>NC_022247.1|WP_021005070.1|401976_402882_+|amino-acid-ABC-transporter-substrate-binding-protein
MKMQLKTLVTAAALLALALGAAAQQAPAGGTLDKIRSSGRAVLGVREASPPMAYMLGANDKYVGYHVELCERVLKDIAPSARLEYMAVTAQNTIPLVQNGTLDIGCGPTTNNTARQQQVAFALTTYVSEVRMATRVDSGISSLDQLAGRTVSASTGTTAVQLLRKRERAQNTTITTMLGKDHLESFLLMESGRADAFVLDDNLLAGIIANAKNPSAYRIVGDALGSEPIALLFRKDDPAFKAAVDDALRRLMKSGELEKIYTRWFVAPIPPKNTSLNLPMSAALKQLIAEPNDKPLEAYAK
>NC_022247.1|WP_021005069.1|400340_401879_+|aldehyde-dehydrogenase-family-protein
MPEAQAPLSVAAEIEPLLQRLGVPSSAHTGGELAVRSPVTGEVIAQVPQTTAAEAAAAIGHAHEAFKAWRSVPAPRRGELVRLLGEELRTAKADLGRLVTLEAGKIPSEGAGEVQEMIDICDFAVGLSRQLYGLTLATERAEHRMMETWHPLGVCGVISAFNFPVAVWSWNAALALVCGDSVVWKPSEKTPLTALAVHAIAQRALARFGDAPEGLLGLLLGQRDIGEVLVDDHRVPILSATGSTAMGRQVGPKLAARFARAILELGGNNAAIVTPSADLDLTLRAIAFSAMGTAGQRCTTLRRLFVHDSVYDALVPKLAKVYGNVQVGDPREAGTLVGPLIDRAAFDGMQKALGESREIGATVHGGQRVEGIGTQDAFYVRPALVELKSHGGPVLRETFAPILYVVRYTSLDDAIEWHNAVGAGLSSSIFTLNVREAERFLSSAGSDCGIANVNIGPSGAEIGGAFGGEKETGGGREAGSDSWKAYMRRATNTINYSTALPLAQGVTFEIND
>NC_022247.1|WP_021005068.1|399312_400173_+|IclR-family-transcriptional-regulator
METPSAASGGVPRVFSVIRALGAVQAEGGRVTQIARSVGLTQATTHRLLQSLMAEGMVEQDERSKLYRLSIDFFALAASAGNPGDLRSICRPVLLRLCASLGDSIFLLARSGFDAICLDRSEGPFPIRSFTGDIGGRIALGVGQGALAILAFLPEAEREEVIRFNLSRVREYGVYDEVYLRTEIERVRQAGYAGRNTGLLEGMAGVAVPILDREGRAVAALSVGTIADRLNADRMPTVVELLKREAAAIGPKINPFDATLRRPAQSLAGSPAGQRISLPEPPGPAT
>NC_022247.1|WP_021005067.1|398038_399109_-|ABC-transporter-ATP-binding-protein
MSFLRLTDVTKFYGATRAVSAMNLTVEKGEFVSLLGPSGCGKTTTLQMIAGFEAVSSGRIELAGKDITHAKANTRGLGIVFQTYALFPHMTVADNVSFGLEMRKMPKSERAERVKQALALVHLEAHATRYPRELSGGQRQRVALARALVIEPPVLLLDEPLSNLDAKLREEMQFELRQIQRKVGTTTVMVTHDQSEAMSISDRVVVMEGGCATQIDHPHRVYEHPSTRFISTFVGKANLLNGRVTASGARSCHVAVGALAVEVDDTAYMPGDAVLMSVRPEKLQLVEAGRGRLDGQVLERFFLGSQWLYRLGTPAGDLMVLSPNDGRDALDEGHAAGIDWPAHCTRLLPADEAVVA
>NC_022247.1|WP_021005066.1|397190_398042_-|ABC-transporter-permease
MKNKATPWWLSGPALLLFVALLVVPLALTAVLSFNVYDPATGPKAGEFTLEHYAQVFTDSYYHGIFWRTFWISGLVTLICVLVGAPEAYVLSRMRNPWRSVLLLVVLAPLLVSVVVRAFGWSMLLGPEGAVNGLLRLAGIGPVKMLYTETAVIVALVHVMLPFMVIPVWTSLQKLDAGVENAALSLKASHVTTLRRIVLPQVMPGILSGSLIVFGLAASSFAIPGLLGGRRLKMVATVVYDEYLHELNWPLGAAVALTLLAANLIVMLSYNRLVEGRYKKALG
>NC_022247.1|WP_021005076.1|408877_410389_-|tripartite-tricarboxylate-transporter-permease
MELFHNLATGFGVAFTFTNLLYCLVGCILGTLIGVLPGIGPVATIAMLLPATYALPPVSALIMLAGIYYGAQYGGSTTAILVNLPGESSSVVTCIDGYQMARQGRAGPALAAAGLGSFFAGCVGTLILAAFAPPLTELAFKFGPAEYFSLMTLGLIGAVVLASGSLLKAVAMIVLGLLLGIVGTDVNSGVARFSFDIPELTDGIGFVVIAMGVFGYGEIIGNLSQPDDEREVFTHKVKGLWPTKDDFKRMTPAVLRGTALGSALGILPGGGALLAAFAAYALEKKIKMRPGEVPFGKGNIRGVASPESANNAGAQTSFIPLLTLGIPPNAVMALMVGAMTIHNIQPGPQVMTSNPELFWGLIASMWIGNAMLIVLNLPLIGMWIKLLTVPYKFLFPAIVLFCAIGVYSTNNNTFDVWMVAIFGFIGYLFLKLRTEPAPLLLGFILGPMMEENLRRALLLSRGAWSVFVTRPLSAGLLVAAALLLGIVLLPSIKAKREEAFVEE
>NC_022247.1|WP_021005077.1|410402_410891_-|tripartite-tricarboxylate-transporter-TctB-family-protein
MRIKSQADFFSGVMFTAVGGAFAIGATTYNIGDGARMGPGYFPLMLGILLAILGAFIMFQAMVVETAGGDKIGKWAWKPLAFVLGANLAFGVLLGGLPSIGLPAMGMIVAIYALTIISSMAGQHFKLRDVLVLSTILAAGSYVAFIWALKLQIQVWPTFISG
>NC_022247.1|WP_021005078.1|411085_411499_-|RNA-binding-protein
MGKKLYVGNLAYSVRDNDLEQAFGEFGSIVSAKVMMERDTGRSKGFGFVEMGTDAEALAAVEAMNGHSLQGRALTVNEARPMEARPPRTGGGGGYGGGAGGGGYGGGGGGGGYGGGGGGRSGGGGGYGGGGGGRGGY
>NC_022247.1|WP_021005079.1|411679_411913_-|DUF3820-family-protein
MKPEDLQRLVTLEMPFGKHKGTLIADLPGNYLNWFAREGFPAGEIGRLLHLMHEIDHNGLSGLLQPLRNRPSGRDVS
>NC_022247.1|WP_021005080.1|411919_412294_-|translation-initiation-factor-Sui1
MATMKCNQVSALVYSTEAGGRMCPDCRAPMAQCRCKETSARIPATDGIVRVSHETKGRKGKGVTVVKGLALDAAALAALGKQLKTACGSGGTVKDGIIEIQGDHRGPVIAALSKQGHTVKRAGG
>NC_022247.1|WP_021005081.1|412353_413625_+|DEAD/DEAH-box-helicase
MPFDSLGLAPALVQAAAESGYAAPTAIQAAAIPAILQGRDVRGSAQTGSGKTAAFSLPLLQRLAAEPAQAPRRVRALVLVPTRELAAQVGETMRSLAQHLPERLKIAIAFGGVSINPQMMSLRGGADIVVATPGRLLDLVDHNALKLGAVSMLVLDEADRLFDLGFAEELGRILALLPAQRQNLLFSATFPPAIQALADGTLRDPAVIDVQGEPGTEPAIVQRVIEVDANRRTQLLRHLLKENDWDRVLVFVATQHAAQTVAEKLYKNGVYAVPFHGDIAQGTRTGILAQFKESRWDVVIATDLAARGIDIAQLPVVINYDLPRSPTDYIHRIGRTGRAGESGLAISFVSAATEAHFRLIEKRQGLHLPRERIEGFEPTEAPVPMVDASGTGGIKGKRPSKKDKLRAAAALAAAQHDAGEKND
>NC_022247.1|WP_021005082.1|413666_414419_-|slipin-family-protein
MFTFGIGTVLLVLLGVLLFSAIWIFREYERGIVFTLGRFSRVAGPGLVIVIPAIQQVVRVDLRTVVLEVPTQDVISRDNVSVKVSAVVYFRIVDAEKAIIEVKDFFNATSQLAQTTLRSVLGKHQLDDMLAEREKLNLDVRESLDVQTASWGIKVSNVEIKQIDLTESMIRAIARQAEAERERRAKVIHAEGELQASEKLFQAARVLAQEPQAIQLRYLETLTVIGADKNTTIIFPLPVDLLASFLHKPA
>NC_022247.1|WP_021005083.1|414517_415681_-|acyl-CoA-dehydrogenase
MDAELRADRAALADTVRRFAESEIAPHVQAWDDLGEFPRALYTRAAELGLLGLGYPEALGGTPASHALKLPAWIALARHGRSGGVLASLFSHNIGLPPVVLHASDAVRSEVVPPVLRGEKIAALAITEPGGGSDVAALRTTARRDGEHYVVNGEKTFITSGMRADWITVAVRTGEERGAGGISMLLVPGDAAGLTRTRLAKMGWWCSDTAQLHFDNVRVPARYLLGEEGAGFRMVMGNFNGERIGLAAGALGFAQACLDEALAWSRERKTFGAALIEHQAVRHKLVDMQMRIASTEAWLEAVSAEGDAHEAAGRFNAPEWVAQVCMLKNHATQTMQFCADQAVQILGGMGFMRGTVSERIYREVKVMMIGGGAEEIMKELAARQMGW
>NC_022247.1|WP_021005084.1|415686_416847_-|acyl-CoA-dehydrogenase
MQYTHEHLEIQKTLRRFIDDEINPHVDEWEEAEIFPAHEVFRKLGSLGMLGLNKPEAFGGAGLDYSYAMAMAEALGHVSCGGVPMAIGVQTDMCTPALARFGSDELRREFLAPAIAGDTVGCIGVSEPGAGSDVAGLKSHARKDGGDYLISGQKMWITNSLQADWMCMLVNTGDGPVHRNKSLVMVPMDSPGIEKAKKIRKIGMHSSDTGLIYFDNVRVPQRYRIGEEGQGFVYQMQQFQEERLWAAASSLEPMEDCIAQTIEWAQQRQMFGATLADQQWVQFKLAELKTEVEALRALAYRACELHVQGQDVLELASMAKLKTGRLTRQVADTCLQFWGGMGFTLENRVSRLYRDGRLGSIGGGADEVMLGILAKTMGIAKRPPRG
>NC_022247.1|WP_021005085.1|416861_417776_-|SDR-family-oxidoreductase
MNASSRYRSVFSPGLFAGQVIVVTGGGSGIGRCTAHELASLGAQVVLVGRKAEKLQQVQAEIAGAGGKASIQAFDIRQEEAVRAAIADIVATHGRIDGLVNNAGGQYITPLAAISAKGWEAVIHTNLTGGFLVARECFVQSMQARGGAIVNIVADMWGSMPHMGHSGAARAGMVSFTETAALEWAASGVRVNAVAPGYIASSGMDHYPTEAGDMLRAMRDTVPAGRFGNEAETSAAIAFLLSPAASFISGSVLRVDGARPQVRMGWPMALPDAQVRQRTAVRPFDGFHLARTPRVFQDGGEPND

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Crispr_ID: NC_022247_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022247_2

4706465-4706562

Orphan

Consensus_repeat	Method
TACCATGAAGGCCGGCAGCGGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022247_2

>merge|NC_022247|2|4706465-4706562|CRISPRCasFinder
TACCATGAAGGCCGGCAGCGGGACCGAGCCGCCTGCCGTCGCATAGGGCGGCATCGTGACCACCGCAGCGCCGGACACCATGAAGGCCGGCAGCGGGA

>NC_022247|2|2|4706465-4706562|CRISPRCasFinder
TACCATGAAGGCCGGCAGCGGGA	CCGAGCCGCCTGCCGTCGCATAGGGCGGCATCGTGACCACCGCAGCGCCGGA
CACCATGAAGGCCGGCAGCGGGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_022247.1\|WP_021008963.1\|4704545_4704779_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008961.1\|4703775_4704168_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_080666819.1\|4713674_4716467_-\|phage-tail-tape-measure-protein	unknown	unknown	gnl\|CDD\|273790
NC_022247.1\|WP_041946558.1\|4713276_4713621_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008974.1\|4718041_4719055_-\|major-capsid-protein	unknown	unknown	gnl\|CDD\|377147
NC_022247.1\|WP_021008971.1\|4716509_4717298_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275042
NC_022247.1\|WP_021008967.1\|4708480_4709665_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008953.1\|4699037_4700063_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008958.1\|4702578_4702848_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008957.1\|4702229_4702541_+\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008962.1\|4704157_4704526_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008966.1\|4707064_4708477_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_155248087.1\|4701762_4702143_+\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008968.1\|4709689_4713274_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008972.1\|4717318_4717729_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008955.1\|4700625_4701642_-\|DUF3578-domain-containing-protein	unknown	unknown	gnl\|CDD\|371900
NC_022247.1\|WP_021008959.1\|4702844_4703198_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008960.1\|4703194_4703779_-\|glycoside-hydrolase-family-19	unknown	unknown	gnl\|CDD\|225720
NC_022247.1\|WP_021008965.1\|4706663_4707068_-\|hypothetical-protein	unknown	unknown	unknown
NC_022247.1\|WP_021008973.1\|4717731_4718028_-\|pro-phage-ATP-binding-sugar-transporter	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_022247.1\|WP_080666819.1\|4713674_4716467_-\|phage-tail-tape-measure-protein	gnl\|CDD\|273790	TIGR01760, COG5283:_Phage-related_tail_protein, phage tail tape measure protein, TP901 family, core region. This model represents a reasonably well conserved core region of a family of phage tail proteins. The member from phage TP901-1 was characterized as a tail length tape measure protein in that a shortened form of the protein leads to phage with proportionately shorter tails. [Mobile and extrachromosomal element functions, Prophage functions].	5.88038e-32
NC_022247.1\|WP_021008955.1\|4700625_4701642_-\|DUF3578-domain-containing-protein	gnl\|CDD\|371900	pfam12102, DUF3578, Domain of unknown function (DUF3578). This presumed domain is functionally uncharacterized. This domain is found in bacteria and archaea. This domain is typically between 177 to 191 amino acids in length.	1.89378e-40
NC_022247.1\|WP_021008974.1\|4718041_4719055_-\|major-capsid-protein	gnl\|CDD\|377147	pfam03864, Phage_cap_E, Phage major capsid protein E. Major capsid protein E is involved with the stabilisation of the condensed form of the DNA molecule in phage heads.	5.0925e-72
NC_022247.1\|WP_021008960.1\|4703194_4703779_-\|glycoside-hydrolase-family-19	gnl\|CDD\|225720	COG3179, COG3179, Predicted chitinase [General function prediction only].	3.4949e-24
NC_022247.1\|WP_021008971.1\|4716509_4717298_-\|hypothetical-protein	gnl\|CDD\|275042	TIGR04189, gliding_motility-related_protein, cell surface protein SprA. SprA is a cell surface protein widely distributed in the Bacteroidetes lineage. In Flavobacterium johnsoniae, a species that shows gliding motility, mutation disrupts gliding.	0.00079072

>NC_022247.1|WP_021008963.1|4704545_4704779_-|hypothetical-protein
MSRNPYSVFLELLPATPLQIATVTAVDGDIARLVLPGGGVLTARGVGDRAIGAEVFVRDGVIEGDAPAGMPLVQFEI
>NC_022247.1|WP_021008962.1|4704157_4704526_-|hypothetical-protein
MDMGDIAGNPIAQLAFLILSAAGGYQVWRKQQPTDAKERADSEGQIAALGTWKELLEGERAARLKAEERADKFAAERNEALKELWEMKGQLRAMNETLAAQTAELSSLRDQVRQLKEQLHAQ
>NC_022247.1|WP_021008961.1|4703775_4704168_-|hypothetical-protein
MHSDSHIDSDRAALEDLPRVRPPRQWRRFFETVGVVGSLFLGGFGSGYFWAARNAEAQITRQREDHLAEIARLREAFGDRLSSLTGRVNRAADTAASAAQTAGEAASTAQTAAQAANQAAKTAAKELKKP
>NC_022247.1|WP_021008960.1|4703194_4703779_-|glycoside-hydrolase-family-19
MIDTQTLIDCTGAARADAERYTLHLADGMNRFGIHSVNAMAAFLGQLAVESDALQKVEENLNYTTPARLREIFPSLFVKGGYRAEEYVRNPRGLSMLRYKGFHGRGLIQLTWEDAYVAAGHALGADFRRHPELLLQPQYAAQSACWFFAVFKDCLPAAERGDVYDVTGRVNGPARLKLAERKAITARAYKVLSK
>NC_022247.1|WP_021008959.1|4702844_4703198_-|hypothetical-protein
MSLLQTLLLALGLSVAGNAALGWAWVGAREKAATTVVERDSARSAASACSDATEDLRDLADKRGAEAKKAQAAARNAATGRQQAAHTILSTPPAVPGDACASARVRVDTWLKGRAQP
>NC_022247.1|WP_021008958.1|4702578_4702848_-|hypothetical-protein
MKRCALIGLAASVAACGVTPMQTVKVPIPIECDVKVPARPAMPTEALSLGVDLDRFSASVLAEIEVREGYEGELRAALIECVKPIRLQR
>NC_022247.1|WP_021008957.1|4702229_4702541_+|hypothetical-protein
MTWLFIQMIDRPKTVMFWGRLFVNVGGLACIAGLWGQLAVKATSELSHPGPASPPTRTLAELYPSLPIWWIPESAFGYALAIGVAALGIWLVTATKRMNRSFR
>NC_022247.1|WP_155248087.1|4701762_4702143_+|hypothetical-protein
MAQSPKLSKTKTPRTTPEEAVARYALMDRAIRQTGFHIDELESALGMYMVGFHFGWRVLYLVHSKRTIKKYESILGLKISEVFPEYGPDADRTNAYKLIQSVSNFWKLVSGDEKPTLQIDKRSLAE
>NC_022247.1|WP_021008955.1|4700625_4701642_-|DUF3578-domain-containing-protein
MGFGDHLREIAQGFQRARTEPLANHPLAALIRQSWPSSLRDSLGGRDAERYQFVGSPGQGQWSAAPWLAVLLHTVTKSAMGGFYPVYLFEPGFQTVCLVMGQGAQQLTDAVGRKRAGVELALRAQQMRANGGRWREQGFNEGPFTTLKFVTTANQRDYAADPWSNTAAFGKRYAVSALPEDAELVADLRAMLQLYDAMAEQRILKFSEEDEELSTLSAAGELPSGSLDGAKKVIVHKQIERRHRDRKLIERVKKQLGVECQACHFDFASAYGSLMEKFIEAHHNVPISTLPDTGAILKPTEADFMVLCSNCHRAIHRAGCPDLMEFKKHHVKGHFYKS
>NC_022247.1|WP_021008953.1|4699037_4700063_-|hypothetical-protein
MREEARVTLLKLKACGYFRWGVNHAPEFGDVVETLRDLNRWGQGKQLGLTKTFDGDESKLPAYLVNVHERRGDWLLTLWNEIESTDGAVASIDGYGQVGDADVTMNEFEAGAIPGFATYFWFMPNEGLVATVRFQHSSAGHYQMNKYLHGFMSQFSPHVVVGEELGDDGEVQVLGYRENDAAALTRFRPRFKSELLRKAGPIDFLLERTDRIRKITKRANLLLEERPKRALWEKMLDQLHLTAPNARPHEVKVNYSVEVDGLSPLALRGIVAEWAQEEQEDNNYGFDLRGESNNTYWLDHAFVKDALWVDIDRKDAEIIEPNSLLSALQGHRRYMLGRANE
>NC_022247.1|WP_021008965.1|4706663_4707068_-|hypothetical-protein
MNVLAINVMLQALVGYLAEGARFMVYGGVQPGEGGAPTTLLAAAVLALPAGAVADGTLALAQADSAGDLALATGVATWGRVELADGTWVADFSMSGPSGAGQVKLVVQNPPEGDPEAKLYQGGTFFLGEVLIGG
>NC_022247.1|WP_021008966.1|4707064_4708477_-|hypothetical-protein
MAASRYWRAINVETYGTGGLEISELQLYYNGVRVDVGATISASMAPASGTLSALQDGSAAETVAWDGATVKSPGFAIYFDLGAAGTSEADAVRVGGGSAQASMISSLVLQNSTDGVTYEGAVPVGRFPWPGANAMTPAPAQTLQLIGAETFATGIPAGFGSVLVDSATLSPVWDAASQAVDLDSSGFNAAWMFGLYAAVNGLRLEFDVEILTANYGNNPMIGAVFKGGPQLLQNFFQHAAAPQAISSARSASATTLGISAIDFNATAPGTLPTSGLHTYVLSSAPNSSGTRDYLMSVDGLGTAFSHGQTPSSAMLTGGIFVRSCKIRLHAVRVYEVIAGGSLLPMLKPATLLGLDVLPPVQPVDAFRVRSTYADIGRKDLEWGGKGRVRGFTLDYVNPVNKPYPCRVRLVRDLDGMVIREAWSGADGGYDFQHIDESQSYSVIAYYLAHGKRAVISDGLTLANGKVELMA
>NC_022247.1|WP_021008967.1|4708480_4709665_-|hypothetical-protein
MASVVDTSVKHFGSFMGAAVPVINGVAGSVIAAIDAFAVNGFDLKSATSLVVSGGVATLAFTGSHSAKVDTVILVAGSSVAALNGEQKVTAVEAGVVRFATAAPDGAASGATTFKMAPLGFLKTFAGVNVATYKPSAPQASGFTLRVDDTLANYAQVRGYEQMTDVNTGIKQFPSTALVGAQNWGKSEVATAAARNWWAFGDARGFYLCIAPGNTYPLNSQCFYFGDLNAYKSGDAFACVLNAFNGTNPHLIASLVNGCVGATSRGVIAGGVARASTGVGGSQYNYAIGAAGFGSDQYSGASNYGLGNYPNQADNALMTHKLLSYQTVNSTWRGAYPGLLHTQQTGAGPAFLPGDIVDGSGALAGRRLLAVRVGPPGGSSYGVIFFDITGGWRD
>NC_022247.1|WP_021008968.1|4709689_4713274_-|hypothetical-protein
MPIFESDIKLVATQVMDDVPEGGGAPTSTVIPDGKSNAIFKDISEVDRAQGDVSIMKVAATVQTLNTDTALGGTVIIARPPLDPNVSAALFVTNDFFDRRAAIQNRLEAYTTPGEEFTGYLLANHVQGQRSMLIFQRPGATPPTVNSTLQLSGGGNTEAVRLTEVKVESRTYSYSTSGGFVDYEAQVCVCELQNGLKHDYAGTPANRLFERTQTAAAINRMLVADAARFYGVSRLVVNASTGDLSVKVDRIDTQIAPTSTTEISITDTSAAGSSIALVRSGAGVVTLNTGALFGPNATLTLGNPFYAGTLSIATSAGTITDDGGRLKLGALTIGTASYVGGTLTFASDAPQIGGTKAITFGPAAAPIELADSASIAVNAENRRVNYPLTILPPPAPGTLRVAYRAGANWYELADDGAGRLRGADSSIGSGTVDYTTGTVAPTLGVLPDVGSEVLYFWGAKANYRDRSGVLPSAVLIRLALDNQAAQASTIAVDWNDGADRHASDNGSGVLTGDATGPVSYATSTIDLRPNTLPASSVAFTVAYSHGSPETKAFPAPARDVDGAITLNLGKTNIAPRSLALSWNLVLMSTGGVPADMWVPQNFASTKTITDDGAGKLVDGLGVEFGTITYATGVAKLYPEAVVTVPVPQWAVNQLGILGTVLSPALPGAFRNTLTGYTYVPLNATLPADASALVTADFRVAGAGTAKSQTFNQPKLSIQLLPNASEVGVPGSVNFTVGGKTYFDRAGALYTDLDPATGAATQAGSYDYATNTASLDVWPASASSTVTVNSLLTALSGQPVEYVVFRTPVAPISPGTLQLLATKLNGGTINVTADMTGFISGANVRGTVDASTGVVKVRFGDWVTAAGNESEPWFHADAVGSDGKIWKPVPVFASTVRYNAVATTSLPVDATLLGLDPVRFPADCRVPIFWKGGLVVIGNTKRLPAAVVSNGQTLSAGRERLSRTRLIGADGLAIETGYTRNLDAGELTVTDASAFAQPVVYEHTIEDMLTLTDVSIDGRLSFASRLSHDYTAGDTYVSSAVRMGDVKARVSLLFDQQSWTGQWSDSLIGNAADPTFNDIDYPITVTNKGAVTERWRIQINGSGTAYNLIGEHVGQIVTGQSLTADCEPVGPSGVPYMRIPAAGFGSGGWPAGSVIRFNTVAATFPFVVIRTVQMGAEAVNDDSFELLVRIGVDRP
>NC_022247.1|WP_041946558.1|4713276_4713621_-|hypothetical-protein
MVWSDEFGWSRVEKSLEYSLTGAALIDAGVRLAGRPITLQGEVDAGWIQRGALSALQALAEANAIGTHALVLADGRTFNVQFAPGLPVEGKPLARPELPVEDYPYIATVRLITV
>NC_022247.1|WP_080666819.1|4713674_4716467_-|phage-tail-tape-measure-protein
MALRWRRHTSPHRPSSQHSPKGFHLAFKPIQILINAKDDASKVFDKLQARLAAFAAVVLGYFGIQAFAGWVKGGADFEQALSRVQAATGATAAEMRALRKAAQEAAADARYGFTELEAAGALENLAKAGLSVRDAIATLPSAMQLARAGDVELATSAEYLTKIVNGLGLSFADAGRVADVLALGANATNTSVAGLAQALSYAAPLANTLGLSLESTVAIVGKFADAGIDASRAGTALNSIFAQFSDPASKFRTELAAAGITSTNFEKALHELAAAGPAGQRAIAAVGQEAGPALRALLNQGVVSLDALTKKLENAKGSAAETAAIMQSNLNGALNALRTAWDSTLNALTTPILPVLKQGVEQLSGALRAAVADGTVAKFGAALALAFQNGIKWVQAFVASVDVPALVAKAQAIADRAGALLDSFGQKAQTTGNIVQTVWGVMVAGANVVLAAIYKQAEGMAMVVSAVQAGIATIIAGLAKITFGGLSAAFKAAAEEVRLSAEATGAVADAFGEKAGQAFDRATEGAEQARAGWAGLTGSAETTTAAATSGAAAFADMAAEMKAAGDSAQEAGQKAASAAEEQRANAEEARASVARLRGEYDQAIATGNLELAAQKLGELKKANLAAADAAGVNKKAQTEAAAEIAAAFQRAGVETKEQLEIAAKTALRDFELIRDSGQATAIGLGEAWKRAAEAAIAAGNGVAPGWVEAQAAMRGFEVVLDSAGRSTLKLRDAQTDAMQAAHGLAGALREVTNARERDIETREKANALKERENALENKRLGRDAKGFSTDKDGKTVNAGSDLGTLTGIAAFLKAAGVSDEKRARAIAMEFADSKGDIPFFNNPGQKKYADGGTLSQALLKAAEKETFFGKGNTPTAIPVPESNRTVNLHLNLNGRDYGTVQTNAAGADAIEDLLAQLGAAAGTSSNRPSR
>NC_022247.1|WP_021008971.1|4716509_4717298_-|hypothetical-protein
MANIYEKSQYIIPRGRVFFDVLDAADQLTGERHLGNCPTVTLNIATEKAPHYSAEAGPGVKDANRVVRIDRTGKITCDNMSADNRAMFISGEKSTVTQATGAVAAEEITVTPGRFYQLGRTDANPAGARKVSDVVVTPDAGGEPYELGVDYTVDAALGRLQILASGGIPAGKIKVAYAKPATTWLRIKSGDKAELRGALRVLSNVAEGEQIDTYCPLVTLAPTGDMSLITSDDAYVQMEFDIEVLTPPNGVAIFEDGRPIEI
>NC_022247.1|WP_021008972.1|4717318_4717729_-|hypothetical-protein
MLALEPVIVSRLRETLDAAWTVKGYTSDKGERPGHALASVMFAAGAVSDVKAGAVALQPGWQVLLSAKQGADAALLLDAAFAEVIASLHNWEPGSAGGRRWGALSLVRFAPPQYPLEGFVGIELLFSTTGRYHGQA
>NC_022247.1|WP_021008973.1|4717731_4718028_-|pro-phage-ATP-binding-sugar-transporter
MEAPFAQIERMVDAGVLGHLANAIATVAGRDVPVIFDDPASHLFDGQVDARAPECSGAMADLGAVVRGDSIVVRGVAYEVMRTDPDGAGFVRLTLGSL
>NC_022247.1|WP_021008974.1|4718041_4719055_-|major-capsid-protein
MDIFSTGVLARVIAELPAPAPFILNSFFRDLQTETSEDIHFDVANGRRRLAPFVAPIVAGKVVQSKGFKTGTFKPAYVKDKRVFDSSRPFKRAIGERIGGELSPAQRQQALLAGDLQDQLEMLARRQEVMAVEALRTGKVTVVGEEYPAVVVDFGRHADLTKALAAGARWGEAGVDPLEDVNEWSMLVTQHSGAAANTLVMDVKAWQLFSAAPSVQKLLDRFRGNDKLNATVVGEGGRYMGNIGDFDIWVYAGWYEDPATETLVPYLPDYTVLITSPDLEGARAYGAIRDEEAGFQAVPYFSKSWVEKDPAVRILLLQSAPLPVPYRVNASFSAKVR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

240432 : 272283

Agrobacterium_phage(25.0%)

transposase,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021004933.1\|240432_240960_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_021004934.1\|240960_242832_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_021004935.1\|242828_243980_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_021004936.1\|243976_246733_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	3.3e-75	28.1
WP_021004938.1\|249137_249611_+	hypothetical protein	NA	NA	NA	NA
WP_021004939.1\|249654_252207_+	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_021004940.1\|252203_253253_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_021004941.1\|253311_253974_+	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_021004942.1\|253986_254367_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_021004943.1\|254422_255241_-	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_021004944.1\|255233_257159_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_021004945.1\|257202_257607_-	hypothetical protein	NA	NA	NA	NA
WP_021004946.1\|257737_258253_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_041945967.1\|258412_259792_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_021004948.1\|259800_261177_+	DotU family type VI secretion system protein	NA	NA	NA	NA
WP_021004949.1\|261176_264812_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_021003967.1\|264825_266049_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.3e-47	29.5
WP_021004950.1\|266287_267013_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_021004951.1\|267038_269192_+	serine/threonine protein kinase	M1HW73	Paramecium_bursaria_Chlorella_virus	4.6e-08	26.0
WP_021004952.1\|270144_270663_-	hypothetical protein	NA	NA	NA	NA
WP_021004953.1\|270714_272283_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	2.5e-133	52.2

DBSCAN-SWA_2

792194 : 800698

Acinetobacter_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021005410.1\|792194_793697_+	anthranilate synthase component I	S4VT78	Pandoravirus	1.1e-35	28.4
WP_021005411.1\|793693_794086_+	GxxExxY protein	A9YW17	Ostreococcus_tauri_virus	1.0e-06	33.0
WP_021005412.1\|794082_794667_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	5.5e-57	55.8
WP_021005413.1\|794673_795732_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_021005414.1\|795748_796408_+	LysE family translocator	NA	NA	NA	NA
WP_021005415.1\|796428_797451_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	5.4e-76	47.2
WP_021005416.1\|797480_798281_+	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	5.2e-58	50.6
WP_021005417.1\|798277_798985_+	uracil-DNA glycosylase	A0A0B5IW78	Pandoravirus	1.5e-48	46.1
WP_021005418.1\|799504_800698_+	elongation factor Tu	A0A1V0SLW6	Klosneuvirus	4.5e-13	28.8

DBSCAN-SWA_3

3749129 : 3756497

Erwinia_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021008098.1\|3749129_3749576_-	dUTP diphosphatase	G0YQD9	Erwinia_phage	4.8e-45	68.7
WP_021008099.1\|3749578_3750028_-	hypothetical protein	NA	NA	NA	NA
WP_021008100.1\|3750027_3751251_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	2.1e-34	31.3
WP_021008101.1\|3751374_3753054_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	5.5e-150	50.8
WP_021008102.1\|3753109_3753967_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	5.8e-47	41.3
WP_021008103.1\|3753963_3754254_+	DUF1330 domain-containing protein	NA	NA	NA	NA
WP_018905898.1\|3754289_3755573_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	7.3e-155	65.0
WP_021008104.1\|3755590_3755869_+	cell division protein FtsB	NA	NA	NA	NA
WP_021008105.1\|3755873_3756497_+	nicotinamide mononucleotide transporter	A0A0F6YPU8	Sinorhizobium_phage	2.9e-08	25.7

DBSCAN-SWA_4

4713674 : 4740727

Pseudomonas_phage(18.18%)

portal,tail,head,capsid,terminase,integrase

attL 4712791:4712807|attR 4749768:4749784

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4712791:4712807	attL	NA	NA	NA	NA
WP_080666819.1\|4713674_4716467_-\|tail	phage tail tape measure protein	Q9G097	Lactococcus_phage	1.0e-28	30.3
WP_021008971.1\|4716509_4717298_-	hypothetical protein	G8DCS4	Silicibacter_phage	2.9e-37	36.5
WP_021008972.1\|4717318_4717729_-	hypothetical protein	NA	NA	NA	NA
WP_021008973.1\|4717731_4718028_-	pro-phage ATP-binding sugar transporter	NA	NA	NA	NA
WP_021008974.1\|4718041_4719055_-\|capsid	major capsid protein	V5Q8G6	Xylella_phage	4.6e-59	38.8
WP_021008975.1\|4719093_4719471_-\|head	head decoration protein	NA	NA	NA	NA
WP_021008976.1\|4719506_4720859_-	S49 family peptidase	K4HZZ6	Acidithiobacillus_phage	1.2e-49	43.8
WP_021008977.1\|4720855_4722484_-\|portal	phage portal protein	A0A2D1GMT8	Marinobacter_phage	4.1e-70	35.2
WP_021008978.1\|4722485_4722713_-	hypothetical protein	NA	NA	NA	NA
WP_021008979.1\|4722837_4726407_-	SIR2 family protein	NA	NA	NA	NA
WP_021008980.1\|4726532_4726862_-	Mor transcription activator family protein	NA	NA	NA	NA
WP_021008981.1\|4726864_4728925_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	4.0e-102	36.8
WP_041946563.1\|4728921_4729440_-	hypothetical protein	NA	NA	NA	NA
WP_021008983.1\|4729624_4730410_-	hypothetical protein	NA	NA	NA	NA
WP_021008984.1\|4730400_4731324_-	helix-turn-helix domain-containing protein	Q6JIG0	Burkholderia_virus	3.7e-23	57.3
WP_021008985.1\|4731364_4731895_-	putative phage regulatory protein	NA	NA	NA	NA
WP_021008986.1\|4731893_4732178_+	hypothetical protein	NA	NA	NA	NA
WP_021008987.1\|4732274_4732487_+	hypothetical protein	NA	NA	NA	NA
WP_021008989.1\|4732848_4733157_+	hypothetical protein	NA	NA	NA	NA
WP_080666869.1\|4733269_4733524_-	helix-turn-helix domain-containing protein	J7I423	Pseudomonas_phage	8.5e-07	54.1
WP_080666820.1\|4733606_4734278_+	LexA family transcriptional regulator	A0A0P0J076	Acinetobacter_phage	1.9e-21	38.3
WP_021008992.1\|4734397_4734652_+	hypothetical protein	NA	NA	NA	NA
WP_021008993.1\|4734656_4735007_+	hypothetical protein	NA	NA	NA	NA
WP_041946194.1\|4735003_4735198_+	hypothetical protein	NA	NA	NA	NA
WP_041946195.1\|4735194_4735701_+	hypothetical protein	NA	NA	NA	NA
WP_021008995.1\|4735697_4735970_+	hypothetical protein	NA	NA	NA	NA
WP_021008997.1\|4736137_4736305_+	hypothetical protein	NA	NA	NA	NA
WP_021008998.1\|4736301_4736643_+	hypothetical protein	NA	NA	NA	NA
WP_021008999.1\|4736674_4736872_+	hypothetical protein	NA	NA	NA	NA
WP_021009000.1\|4736868_4737585_+	HD domain-containing protein	A0A192Y8M4	Salmonella_phage	1.1e-06	29.9
WP_021009001.1\|4737671_4737848_+	phage transcriptional regulator AlpA	NA	NA	NA	NA
WP_080666821.1\|4737844_4739485_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_021009003.1\|4739578_4740727_-\|integrase	tyrosine-type recombinase/integrase	A0A1B0VMI6	Pseudomonas_phage	3.6e-60	38.5
4749768:4749784	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022247

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection