CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022238	Streptococcus constellatus subsp. pharyngis C1050, complete sequence	0 crisprs	cas3,csa3,DinG,RT,csm6,DEDDh	0	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

64407 : 87404

Streptococcus_phage(81.82%)

integrase

attL 63046:63062|attR 81808:81824

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
63046:63062	attL	NA	NA	NA	NA
WP_001291561.1\|64407_65625_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|65706_65910_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_000857133.1\|66370_66601_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000804885.1\|66597_67020_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_001227347.1\|67524_67878_+	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000336323.1\|67937_68105_-	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_000691727.1\|68223_70143_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	100.0
WP_001791010.1\|70158_70275_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224319.1\|70519_71452_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-171	100.0
WP_000769868.1\|71448_72450_-	bifunctional lysozyme/C40 family peptidase	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_000804748.1\|72446_74624_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000331160.1\|74626_77074_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000506270.1\|77057_77564_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|77538_78036_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|78152_78374_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000398284.1\|78416_79622_-	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_000879507.1\|79644_79797_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|79799_81185_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|81213_81600_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_020999306.1\|81615_81930_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	2.6e-53	99.0
81808:81824	attR	NA	NA	NA	NA
WP_006269197.1\|82750_83533_-	AAC(3) family N-acetyltransferase	O64018	Bacillus_phage	1.5e-49	45.0
WP_020997525.1\|83593_84031_-	GNAT family N-acetyltransferase	E3T5G3	Cafeteria_roenbergensis_virus	1.6e-05	32.0
WP_037592430.1\|84030_84471_-	hypothetical protein	NA	NA	NA	NA
WP_020997527.1\|84583_85234_-	ABC-2 transporter permease	NA	NA	NA	NA
WP_006269178.1\|85233_85977_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-21	31.3
WP_006269106.1\|85969_86185_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_020997528.1\|86405_87404_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.5e-06	30.8

DBSCAN-SWA_2

394807 : 402305

environmental_halophage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020997620.1\|394807_396040_+	cysteine desulfurase	Q2XUY6	environmental_halophage	5.3e-102	44.1
WP_006267344.1\|396026_396476_+	SUF system NifU family Fe-S cluster assembly protein	A0A218MKD1	uncultured_virus	1.4e-07	29.9
WP_006267406.1\|396565_397807_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	4.0e-17	24.3
WP_020997621.1\|397961_399305_+	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.2e-45	30.2
WP_003070284.1\|399464_400274_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_006267627.1\|400273_401017_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.4e-27	38.7
WP_003070280.1\|401106_401331_+	DUF4059 family protein	NA	NA	NA	NA
WP_006267441.1\|401393_402305_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	5.5e-88	52.8

DBSCAN-SWA_3

516296 : 579623

Streptococcus_phage(30.0%)

tRNA,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020997660.1\|516296_517061_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.6e-16	26.5
WP_006267199.1\|517060_517771_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.2e-15	26.2
WP_006267402.1\|517918_518575_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	7.2e-82	71.3
WP_006267641.1\|518632_519496_-	YitT family protein	M1Q1P6	Streptococcus_phage	1.3e-91	56.8
WP_006267120.1\|519648_520287_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.4e-74	66.7
WP_020997662.1\|520283_521177_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.8e-83	56.1
WP_003025601.1\|521210_521528_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	8.1e-31	62.9
WP_006267267.1\|521530_522394_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	4.8e-110	71.5
WP_003034287.1\|522405_522915_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	3.2e-53	62.8
WP_003034329.1\|522932_523286_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.0e-37	65.0
WP_003034261.1\|523421_524045_+	endonuclease III	NA	NA	NA	NA
WP_006267616.1\|524070_524898_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.4e-119	75.1
WP_020997663.1\|525013_525247_+	hypothetical protein	NA	NA	NA	NA
WP_020997664.1\|525615_526515_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003070009.1\|526501_526780_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_006267080.1\|526769_527405_+	SdpI family protein	NA	NA	NA	NA
WP_006267603.1\|527661_528117_+	DUF3290 family protein	NA	NA	NA	NA
WP_006267384.1\|528113_528746_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_006267469.1\|529109_529370_-	membrane protein	NA	NA	NA	NA
WP_006267251.1\|529616_531614_+\|tRNA	methionine--tRNA ligase	A0A1V0SEZ7	Hokovirus	2.7e-87	31.7
WP_003069999.1\|532975_533662_+	response regulator transcription factor	A0A220YL79	Alteromonas_virus	5.7e-05	24.1
WP_020997667.1\|533645_534626_+	sensor histidine kinase	A0A2K9L0Z8	Tupanvirus	4.3e-06	27.4
WP_006267137.1\|534749_535508_+	beta-carotene 15,15'-monooxygenase	NA	NA	NA	NA
WP_006267387.1\|535761_536529_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.5e-25	33.8
WP_006267657.1\|536521_538510_+	ABC transporter permease	NA	NA	NA	NA
WP_006267214.1\|538656_540045_+	amino acid permease	NA	NA	NA	NA
WP_020997668.1\|540113_540542_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_006267324.1\|540554_541016_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_006267437.1\|541012_541666_+	RpiB/LacA/LacB family sugar-phosphate isomerase	NA	NA	NA	NA
WP_003032129.1\|541782_541986_-	cold-shock protein	Q9AZD3	Lactococcus_phage	3.3e-25	83.1
WP_003025500.1\|542177_542414_+	DUF2829 domain-containing protein	G3MBC9	Bacillus_virus	1.1e-05	38.6
WP_020997669.1\|542406_543105_+	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	3.2e-11	25.2
WP_020997670.1\|543125_543863_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_006267613.1\|544279_544720_+	ASCH domain-containing protein	NA	NA	NA	NA
WP_003069958.1\|544813_546193_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	5.5e-31	36.0
WP_006267518.1\|546201_546753_+	NUDIX hydrolase	NA	NA	NA	NA
WP_003025491.1\|546763_547072_+	hypothetical protein	NA	NA	NA	NA
WP_006267211.1\|547123_547816_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_006267245.1\|548253_549795_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.0e-54	28.5
WP_006270123.1\|549981_550782_-	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	4.2e-15	38.1
WP_158460125.1\|551218_551404_+	hypothetical protein	NA	NA	NA	NA
WP_003032121.1\|551489_551699_+	PspC domain-containing protein	NA	NA	NA	NA
WP_006267482.1\|551785_554083_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	4.2e-84	50.1
WP_020997672.1\|554335_556714_+	cation-translocating P-type ATPase	A0A218MNH6	uncultured_virus	5.9e-17	21.9
WP_020997673.1\|556730_557084_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_003069940.1\|557245_557671_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_003069939.1\|557760_558450_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_003034339.1\|558735_559476_+	UMP kinase	NA	NA	NA	NA
WP_006267182.1\|559479_560037_+	ribosome recycling factor	NA	NA	NA	NA
WP_006267155.1\|560149_561004_+	RNA-binding virulence regulatory protein CvfB	NA	NA	NA	NA
WP_020997674.1\|561084_562662_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	3.6e-111	43.6
WP_006267249.1\|562651_563647_+	virulence RhuM family protein	Q9JMN3	Wolbachia_phage	2.3e-63	42.2
WP_006267102.1\|563646_564801_+	restriction endonuclease subunit S	A0A1V0SLK8	Klosneuvirus	1.3e-06	25.5
WP_006267598.1\|564860_565379_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_020997675.1\|565436_568481_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	3.3e-28	23.6
WP_006267208.1\|568534_569572_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_006267096.1\|569642_570248_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	5.9e-62	56.2
WP_022525583.1\|570320_570695_-	hypothetical protein	NA	NA	NA	NA
WP_006267089.1\|571178_573329_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	3.2e-38	28.0
WP_020999319.1\|573339_574701_+\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_003037249.1\|574797_574947_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_020997678.1\|574991_576299_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_020997679.1\|576303_577056_-	response regulator transcription factor	A0A1V0E029	Clostridioides_phage	2.5e-14	25.0
WP_020997680.1\|577218_577932_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_006267535.1\|578163_578385_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_006267159.1\|579061_579382_+	hypothetical protein	NA	NA	NA	NA
WP_003025420.1\|579389_579623_+\|bacteriocin	garvicin Q family class II bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_4

1067411 : 1076364

Bacillus_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006267937.1\|1067411_1069148_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	8.4e-45	28.0
WP_020997828.1\|1069361_1070159_-	formate/nitrite transporter family protein	NA	NA	NA	NA
WP_020997829.1\|1070333_1071041_-	glucosaminidase domain-containing protein	Q9ZXE4	Bacillus_phage	7.4e-16	41.6
WP_020997830.1\|1071365_1071953_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_006267807.1\|1071965_1073198_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	5.4e-131	57.7
WP_003024903.1\|1073251_1073425_-	hypothetical protein	NA	NA	NA	NA
WP_006267777.1\|1073424_1073937_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	9.1e-24	38.5
WP_006267886.1\|1074221_1075061_-	thymidylate synthase	U5J9N5	Bacillus_phage	6.2e-86	56.4
WP_006267929.1\|1075146_1076364_-	chloride channel protein	A0A1X9I5Z9	Streptococcus_phage	2.1e-95	51.7

DBSCAN-SWA_5

1130608 : 1191397

Streptococcus_phage(94.74%)

holin,tail,protease,head,capsid,terminase,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006267901.1\|1130608_1131313_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_020997850.1\|1132345_1134007_-	ribonuclease J	NA	NA	NA	NA
WP_006267751.1\|1134704_1135991_-	U32 family peptidase	Q6DW11	Phage_TP	3.3e-38	30.9
WP_006267951.1\|1136119_1137049_-	U32 family peptidase	NA	NA	NA	NA
WP_020997851.1\|1137187_1137475_+	DUF3270 domain-containing protein	NA	NA	NA	NA
WP_020997852.1\|1137564_1138038_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_020997853.1\|1138053_1138437_-	DUF948 domain-containing protein	NA	NA	NA	NA
WP_006270687.1\|1138454_1139228_-	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_003068730.1\|1139220_1140153_-	HPr kinase/phosphorylase	NA	NA	NA	NA
WP_020997854.1\|1140263_1140785_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_037591159.1\|1140834_1141107_-	PspC domain-containing protein	NA	NA	NA	NA
WP_020997855.1\|1141207_1141645_-	SprT family protein	NA	NA	NA	NA
WP_006268717.1\|1141631_1143761_-	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_003072333.1\|1143879_1144020_+	hypothetical protein	NA	NA	NA	NA
WP_006268704.1\|1144016_1144922_+	permease	NA	NA	NA	NA
WP_006268763.1\|1144918_1145734_+	TIGR03943 family protein	NA	NA	NA	NA
WP_006268693.1\|1145848_1147213_+	MFS transporter	NA	NA	NA	NA
WP_006268592.1\|1147260_1148748_+	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	3.4e-71	35.0
WP_020997856.1\|1148800_1150303_-	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
WP_020997857.1\|1150315_1151128_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_006268771.1\|1151127_1151919_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_020997858.1\|1153619_1154828_-	recombinase family protein	M1NSJ1	Streptococcus_phage	5.5e-104	49.1
WP_006268681.1\|1154884_1155046_-	hypothetical protein	Q6DMS7	Streptococcus_phage	8.3e-08	56.9
WP_006268639.1\|1155042_1155444_-	sigma-70 region 4 domain-containing protein	NA	NA	NA	NA
WP_006268683.1\|1155553_1157023_-	N-acetylmuramoyl-L-alanine amidase	A0A1X9I678	Streptococcus_phage	4.4e-228	79.1
WP_020997859.1\|1157024_1157429_-\|holin	phage holin family protein	D0R0E9	Streptococcus_phage	3.0e-46	75.6
WP_006268669.1\|1157446_1159303_-	hypothetical protein	Q6DMS9	Streptococcus_phage	1.8e-258	73.4
WP_020999392.1\|1159315_1162231_-\|tail	phage tail protein	Q6DMT0	Streptococcus_phage	0.0e+00	64.9
WP_020997861.1\|1162230_1162956_-	hypothetical protein	Q6DMT1	Streptococcus_phage	3.0e-81	58.3
WP_006268614.1\|1162952_1166072_-\|tail	phage tail tape measure protein	Q6DMT2	Streptococcus_phage	8.0e-256	71.3
WP_001249612.1\|1166254_1166674_-	hypothetical protein	A0A1X9I691	Streptococcus_phage	1.3e-57	78.4
WP_006268577.1\|1166685_1167255_-	hypothetical protein	A0A1B0RXE2	Streptococcus_phage	3.6e-98	94.7
WP_006268732.1\|1167257_1167584_-	hypothetical protein	M1Q1Z4	Streptococcus_phage	1.4e-38	68.5
WP_006268594.1\|1167592_1167961_-	hypothetical protein	A0A1X9I688	Streptococcus_phage	1.0e-32	57.4
WP_006268724.1\|1167953_1168292_-\|head,tail	head-tail adaptor protein	A0A1B0RXE4	Streptococcus_phage	4.0e-36	67.9
WP_006268626.1\|1168291_1168549_-\|head,tail	phage gp6-like head-tail connector protein	D0R0D7	Streptococcus_phage	1.0e-31	82.4
WP_020997862.1\|1168545_1169754_-\|capsid	phage major capsid protein	M1Q1R5	Streptococcus_phage	2.0e-210	90.8
WP_006268741.1\|1169767_1170466_-\|protease	Clp protease ClpP	A0A1B0RXE1	Streptococcus_phage	8.4e-105	82.8
WP_020997863.1\|1170440_1171748_-\|portal	phage portal protein	A0A1B0RXD8	Streptococcus_phage	9.2e-230	90.7
WP_006268711.1\|1172126_1173719_-\|terminase	terminase large subunit	A0A1B0RXJ8	Streptococcus_phage	4.6e-308	95.8
WP_020997864.1\|1173715_1174189_-\|terminase	phage terminase small subunit P27 family	A0A1X9I6K0	Streptococcus_phage	6.6e-85	97.5
WP_041786238.1\|1174237_1174447_-	DUF4314 domain-containing protein	A0A1X9I6A3	Streptococcus_phage	5.0e-21	69.6
WP_006268742.1\|1174448_1174703_-	hypothetical protein	M1NSE3	Streptococcus_phage	5.2e-20	54.9
WP_020997865.1\|1174764_1176045_-	DNA (cytosine-5-)-methyltransferase	M1NSK8	Streptococcus_phage	1.5e-229	91.1
WP_006268630.1\|1176041_1177298_-	DNA modification methylase	A0A1B0RXE5	Streptococcus_phage	2.3e-225	91.8
WP_020997866.1\|1177269_1177725_-	hypothetical protein	A0A1X9I6V0	Streptococcus_phage	7.5e-46	53.6
WP_020997867.1\|1178044_1178410_-	HNH endonuclease	E4ZFL2	Streptococcus_phage	7.8e-62	86.8
WP_006268720.1\|1179500_1179683_-	hypothetical protein	A0A1B0RXC3	Streptococcus_phage	3.7e-20	86.7
WP_006268755.1\|1179876_1180353_-	hypothetical protein	A0A1B0RXB9	Streptococcus_phage	4.6e-70	82.3
WP_006268649.1\|1180345_1181722_-	DEAD/DEAH box helicase	A0A1X9I6B0	Streptococcus_phage	5.3e-228	85.2
WP_020997868.1\|1181702_1181984_-	VRR-NUC domain-containing protein	M1PFY8	Streptococcus_phage	1.6e-38	80.6
WP_006268625.1\|1182265_1184554_-	hypothetical protein	Q6DMV9	Streptococcus_phage	0.0e+00	87.0
WP_006268776.1\|1184913_1185237_+	hypothetical protein	D0R0B4	Streptococcus_phage	1.5e-32	72.9
WP_020997869.1\|1185229_1186351_+	DUF2800 domain-containing protein	A0A1B0RXB8	Streptococcus_phage	1.2e-196	88.4
WP_006268572.1\|1186355_1186919_+	DUF2815 family protein	A0A1B0RXA9	Streptococcus_phage	2.1e-90	91.7
WP_006268608.1\|1186937_1187105_+	hypothetical protein	E4ZFK2	Streptococcus_phage	5.1e-08	58.8
WP_037592464.1\|1187159_1190036_+	DNA polymerase	D0R0B0	Streptococcus_phage	4.0e-302	58.0
WP_006268767.1\|1190084_1190594_-	type III toxin-antitoxin system ToxN/AbiQ family toxin	NA	NA	NA	NA
WP_006268654.1\|1190800_1191397_-	hypothetical protein	M1Q222	Streptococcus_phage	2.5e-12	28.9

DBSCAN-SWA_6

1213441 : 1280751

Erysipelothrix_phage(38.46%)

holin,portal,tail,protease,head,capsid,terminase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003068684.1\|1213441_1214446_-	catabolite control protein A	C6ZCU4	Enterobacteria_phage	3.4e-22	27.5
WP_020997877.1\|1214710_1215793_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_006268725.1\|1216315_1216897_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_020997878.1\|1217215_1218235_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	6.6e-90	48.5
WP_020997879.1\|1218269_1219316_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	3.5e-70	44.2
WP_020997880.1\|1219347_1219941_-	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	H9NC63	Sphingomonas_phage	5.1e-10	33.1
WP_006268635.1\|1219944_1220814_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	1.9e-101	64.2
WP_020997881.1\|1220956_1221427_-	8-oxo-dGTP diphosphatase	A0A1W6DX89	Sphingobium_phage	1.6e-06	31.8
WP_006268591.1\|1221427_1222525_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_006268575.1\|1223320_1224010_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_080654537.1\|1224353_1225082_-	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_006268606.1\|1225072_1225462_-	hypothetical protein	NA	NA	NA	NA
WP_020997883.1\|1225506_1227249_-	rhamnan synthesis protein F	NA	NA	NA	NA
WP_006268768.1\|1227250_1228660_-	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	2.7e-09	36.8
WP_020997884.1\|1228672_1229896_-	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.6e-12	24.9
WP_006268576.1\|1229895_1230705_-	ABC transporter permease	NA	NA	NA	NA
WP_006268676.1\|1230707_1231643_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_020997885.1\|1231639_1232788_-	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_003068630.1\|1232890_1233742_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.1e-25	35.0
WP_020997886.1\|1233816_1234743_-	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	6.6e-73	47.2
WP_020997887.1\|1236197_1237715_-	DUF2142 domain-containing protein	NA	NA	NA	NA
WP_020997888.1\|1237721_1238867_-	glycosyltransferase	NA	NA	NA	NA
WP_020997889.1\|1238859_1240140_-	hypothetical protein	NA	NA	NA	NA
WP_020997890.1\|1240123_1240465_-	DUF2304 domain-containing protein	NA	NA	NA	NA
WP_006268708.1\|1240472_1241168_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_006268613.1\|1241495_1241981_-	thioesterase	NA	NA	NA	NA
WP_020997891.1\|1242453_1242777_-	hypothetical protein	NA	NA	NA	NA
WP_006268583.1\|1243273_1243891_-	RpiB/LacA/LacB family sugar-phosphate isomerase	NA	NA	NA	NA
WP_006268714.1\|1243917_1244238_-	TfoX/Sxy family protein	NA	NA	NA	NA
WP_020997892.1\|1244259_1244688_-	VOC family protein	NA	NA	NA	NA
WP_006268677.1\|1244714_1245332_-	DNA alkylation repair protein	NA	NA	NA	NA
WP_006268628.1\|1245514_1245715_-	DNA-binding protein	NA	NA	NA	NA
WP_020997894.1\|1245843_1247415_-	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	4.2e-152	52.6
WP_006268605.1\|1247407_1247824_-	hypothetical protein	A0A2K5B2B3	Erysipelothrix_phage	1.1e-24	45.3
WP_006268700.1\|1247820_1249386_-	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	8.7e-134	47.4
WP_020997896.1\|1249445_1249661_-	hypothetical protein	NA	NA	NA	NA
WP_020997897.1\|1249647_1250058_-	helix-turn-helix domain-containing protein	A0A1B0RXC6	Streptococcus_phage	4.0e-22	40.0
WP_006268703.1\|1250241_1251228_-	N-acetylmuramoyl-L-alanine amidase	A0A2K9V338	Faecalibacterium_phage	5.1e-47	50.8
WP_006268587.1\|1251220_1251640_-\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	2.4e-46	69.5
WP_006268727.1\|1251641_1252154_-	hypothetical protein	NA	NA	NA	NA
WP_020997898.1\|1252163_1252757_-	hypothetical protein	NA	NA	NA	NA
WP_006268695.1\|1252771_1252984_-	hypothetical protein	NA	NA	NA	NA
WP_006268751.1\|1252983_1253280_-	hypothetical protein	NA	NA	NA	NA
WP_006268680.1\|1253291_1253573_-	hypothetical protein	NA	NA	NA	NA
WP_006268740.1\|1253553_1253736_-	hypothetical protein	NA	NA	NA	NA
WP_020997899.1\|1253745_1256571_-\|tail	phage tail protein	H7BV46	unidentified_phage	3.2e-110	29.9
WP_020997900.1\|1256571_1257246_-	hypothetical protein	A0A2K9V3E8	Faecalibacterium_phage	6.4e-17	32.0
WP_006268627.1\|1257248_1260062_-\|tail	phage tail tape measure protein	Q6DMT2	Streptococcus_phage	1.4e-60	28.7
WP_020997901.1\|1260164_1260581_-	YjdF family protein	NA	NA	NA	NA
WP_006268664.1\|1260788_1260953_-	hypothetical protein	NA	NA	NA	NA
WP_020997902.1\|1260960_1261314_-	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	2.4e-07	34.2
WP_006268675.1\|1261325_1261916_-\|tail	tail protein	A0A0U4JWV5	Exiguobacterium_phage	6.6e-42	49.5
WP_006268602.1\|1261905_1262238_-	hypothetical protein	Q6DMT6	Streptococcus_phage	6.8e-20	46.8
WP_006268735.1\|1262230_1262611_-	HK97 gp10 family phage protein	A0A2H4JAN0	uncultured_Caudovirales_phage	1.3e-14	35.2
WP_006268585.1\|1262607_1262940_-\|head	phage head closure protein	NA	NA	NA	NA
WP_006268774.1\|1262939_1263218_-\|head,tail	phage gp6-like head-tail connector protein	A0A1B0RXK2	Streptococcus_phage	5.7e-12	41.5
WP_006268656.1\|1263240_1264416_-\|capsid	phage major capsid protein	M1Q1R5	Streptococcus_phage	3.0e-102	50.6
WP_051146972.1\|1264422_1265130_-\|protease	Clp protease ClpP	Q6DMU1	Streptococcus_phage	5.6e-64	62.2
WP_020997904.1\|1265080_1266427_-\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	1.4e-169	70.3
WP_020997905.1\|1266528_1267254_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_022525563.1\|1267340_1268933_-\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	1.6e-263	82.0
WP_006268702.1\|1269102_1269381_-	hypothetical protein	NA	NA	NA	NA
WP_006268586.1\|1269468_1269642_-	DUF5049 domain-containing protein	NA	NA	NA	NA
WP_006268604.1\|1269631_1269862_-	DUF4314 domain-containing protein	A0A2K5B281	Erysipelothrix_phage	2.6e-18	61.4
WP_006268633.1\|1269845_1270496_-	hypothetical protein	A0A2K5B280	Erysipelothrix_phage	2.4e-45	45.0
WP_006268599.1\|1270531_1272049_-	DNA (cytosine-5-)-methyltransferase	A0A1P8DJM9	Virus_Rctr41k	1.6e-36	30.1
WP_022525564.1\|1272041_1273277_-	site-specific DNA-methyltransferase	A0A2I4R670	Erysipelothrix_phage	1.1e-139	59.9
WP_006268739.1\|1273289_1274072_-	methionine adenosyltransferase	NA	NA	NA	NA
WP_020997908.1\|1274075_1274720_-	hypothetical protein	A0A2K5B277	Erysipelothrix_phage	1.0e-40	45.3
WP_020997909.1\|1274762_1275128_-	HNH endonuclease	A0A2K5B276	Erysipelothrix_phage	8.2e-35	54.6
WP_022525566.1\|1275240_1275711_-	hypothetical protein	A0A2K5B275	Erysipelothrix_phage	4.8e-19	39.4
WP_020997911.1\|1275758_1277102_-	DEAD/DEAH box helicase	A0A2K5B273	Erysipelothrix_phage	6.9e-172	74.6
WP_020997912.1\|1277082_1277364_-	VRR-NUC domain-containing protein	A0A1B0RXC4	Streptococcus_phage	8.8e-21	57.8
WP_022525568.1\|1279712_1280084_-	hypothetical protein	A0A2K5B270	Erysipelothrix_phage	7.5e-28	50.0
WP_006268684.1\|1280076_1280751_-	Rha family transcriptional regulator	A0A2K5B268	Erysipelothrix_phage	1.3e-86	67.1

DBSCAN-SWA_7

1490114 : 1500542

Streptococcus_phage(90.0%)

terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006268376.1\|1490114_1490390_-\|terminase	terminase small subunit	A0A1P8VVN7	Streptococcus_phage	4.9e-32	88.8
WP_022525741.1\|1490469_1490700_-	hypothetical protein	NA	NA	NA	NA
WP_006268286.1\|1490938_1491349_-	hypothetical protein	K4JTJ9	Streptococcus_phage	1.7e-36	59.7
WP_006268241.1\|1491329_1491812_-	hypothetical protein	A0A1S5SEB0	Streptococcus_phage	2.9e-27	47.3
WP_006268172.1\|1491830_1492211_-	hypothetical protein	NA	NA	NA	NA
WP_006268092.1\|1492235_1492445_-	hypothetical protein	NA	NA	NA	NA
WP_006267997.1\|1492524_1492701_-	hypothetical protein	NA	NA	NA	NA
WP_006268458.1\|1493020_1493512_-	hypothetical protein	A7J274	Streptococcus_phage	1.2e-09	33.3
WP_006268118.1\|1493830_1494685_-	ATP-binding protein	M1PFI4	Streptococcus_phage	1.4e-72	49.6
WP_006268372.1\|1494696_1495518_-	DnaD domain protein	A0A2I6QQV2	Streptococcus_phage	8.7e-85	69.3
WP_006268001.1\|1495510_1495705_-	hypothetical protein	NA	NA	NA	NA
WP_006268135.1\|1495716_1495983_-	HTH domain-containing protein	A0A1X9I6M4	Streptococcus_phage	4.9e-29	75.9
WP_037592809.1\|1495993_1496185_-	hypothetical protein	NA	NA	NA	NA
WP_006268000.1\|1496393_1496582_-	hypothetical protein	A0A1X9I5U7	Streptococcus_phage	1.7e-20	82.3
WP_020997978.1\|1496752_1497340_+	helix-turn-helix transcriptional regulator	O34051	Streptococcus_phage	1.1e-12	55.2
WP_003036126.1\|1498806_1499499_-	phosphoglycerate mutase	NA	NA	NA	NA
WP_003035860.1\|1499636_1500098_-	transcriptional repressor	NA	NA	NA	NA
WP_003036014.1\|1500266_1500542_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	1.3e-24	69.7

DBSCAN-SWA_8

1968836 : 1977683

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006268841.1\|1968836_1969676_-	energy-coupling factor transporter ATPase	A0A2K9L3Z8	Tupanvirus	1.5e-15	32.1
WP_006270357.1\|1969660_1970488_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	1.8e-21	31.8
WP_006270330.1\|1970489_1971029_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_020998125.1\|1971039_1971861_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_006268797.1\|1971919_1973215_-	insulinase family protein	A0A1E1EST3	Acanthamoeba_castellanii_mimivirus	3.1e-20	26.0
WP_020998126.1\|1973214_1974462_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	4.2e-115	51.4
WP_020998127.1\|1974636_1975017_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	1.1e-18	61.3
WP_020998128.1\|1975019_1976117_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_003071643.1\|1976201_1977683_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	8.1e-97	40.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage