CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022442	Staphylococcus aureus subsp. aureus SA957, complete sequence	10 crisprs	cas3,DEDDh,DinG,csa3,WYL	4	2	11	1

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_022442_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022442_1

769583-769668

Orphan

Consensus_repeat	Method
CAATGCGAGTTGGGGTGGGGCCCCAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022442_1

>merge|NC_022442|1|769583-769668|CRISPRCasFinder
CAATGCGAGTTGGGGTGGGGCCCCAACACAGAGAAATTGGAACGCCAATTTCTACAGGCAATGCGAGTTGGGGTGGGCCCCAACAT

>NC_022442|1|1|769583-769668|CRISPRCasFinder
CAATGCGAGTTGGGGTGGGGCCCCAACA	CAGAGAAATTGGAACGCCAATTTCTACAGG
CAATGCGAGTTGGGGTGGGCCCCAACAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_022442.1\|WP_000663039.1\|767734_768793_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
NC_022442.1\|WP_014363392.1\|756426_756633_+\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000022323.1\|757423_758428_+\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224895
NC_022442.1\|WP_000692521.1\|775321_775720_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|224694
NC_022442.1\|WP_000876317.1\|779570_780542_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226965
NC_022442.1\|WP_000197262.1\|768951_769494_+\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
NC_022442.1\|WP_000525113.1\|761112_762996_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NC_022442.1\|WP_000589262.1\|765010_765988_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NC_022442.1\|WP_000180997.1\|765980_767495_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NC_022442.1\|WP_031760357.1\|771111_771213_+\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000983680.1\|763007_764789_+\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
NC_022442.1\|WP_000193751.1\|771290_772796_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NC_022442.1\|WP_000855509.1\|775682_777788_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
NC_022442.1\|WP_001068497.1\|773655_774522_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NC_022442.1\|WP_000098285.1\|758901_760842_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	unknown	unknown	gnl\|CDD\|224287
NC_022442.1\|WP_000429011.1\|770101_771019_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NC_022442.1\|WP_000708692.1\|756729_757440_+\|allophanate-hydrolase-subunit-1	unknown	unknown	gnl\|CDD\|224960
NC_022442.1\|WP_000499195.1\|779376_779532_+\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000562498.1\|777905_778877_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NC_022442.1\|WP_000930014.1\|773135_773636_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|223851

Protein	Function_ID	Function_description	E-value
NC_022442.1\|WP_000663039.1\|767734_768793_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
NC_022442.1\|WP_000022323.1\|757423_758428_+\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.25641e-144
NC_022442.1\|WP_000692521.1\|775321_775720_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
NC_022442.1\|WP_000876317.1\|779570_780542_+\|ABC-transporter-permease	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	6.82559e-150
NC_022442.1\|WP_000197262.1\|768951_769494_+\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	3.14113e-108
NC_022442.1\|WP_000525113.1\|761112_762996_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_022442.1\|WP_000589262.1\|765010_765988_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	3.31335e-155
NC_022442.1\|WP_000180997.1\|765980_767495_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.75128e-152
NC_022442.1\|WP_000983680.1\|763007_764789_+\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_022442.1\|WP_000193751.1\|771290_772796_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
NC_022442.1\|WP_000855509.1\|775682_777788_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NC_022442.1\|WP_001068497.1\|773655_774522_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.8323e-10
NC_022442.1\|WP_000098285.1\|758901_760842_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NC_022442.1\|WP_000429011.1\|770101_771019_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	1.47588e-77
NC_022442.1\|WP_000708692.1\|756729_757440_+\|allophanate-hydrolase-subunit-1	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.29969e-94
NC_022442.1\|WP_000562498.1\|777905_778877_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
NC_022442.1\|WP_000930014.1\|773135_773636_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79

>NC_022442.1|WP_000197262.1|768951_769494_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>NC_022442.1|WP_000663039.1|767734_768793_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISSHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEHFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NC_022442.1|WP_000180997.1|765980_767495_+|ABC-transporter-permease/substrate-binding-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRLMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>NC_022442.1|WP_000589262.1|765010_765988_+|ABC-transporter-ATP-binding-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLEMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTTMSAYPIVYDNQQIEVLYQHLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>NC_022442.1|WP_000983680.1|763007_764789_+|DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFVLDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>NC_022442.1|WP_000525113.1|761112_762996_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MGMEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMMDAQEAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNVLSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREESEIAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSSTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>NC_022442.1|WP_000098285.1|758901_760842_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>NC_022442.1|WP_000022323.1|757423_758428_+|biotin-dependent-carboxyltransferase-family-protein
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>NC_022442.1|WP_000708692.1|756729_757440_+|allophanate-hydrolase-subunit-1
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDLESLLKHYKIKLETFIELHSKAQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>NC_022442.1|WP_014363392.1|756426_756633_+|hypothetical-protein
MIIVYIALLLILVYVNYRLVNRLLSENRIYVVRLIATITTVISFILVYALIHELMPFVVRAMDLMYHQ
>NC_022442.1|WP_000429011.1|770101_771019_-|diacylglycerol-kinase-family-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMTHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILSANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NC_022442.1|WP_031760357.1|771111_771213_+|hypothetical-protein
MVITDIDVYRVGRENIVIAVYNEHIKLLFILIS
>NC_022442.1|WP_000193751.1|771290_772796_-|peptide-MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NC_022442.1|WP_000930014.1|773135_773636_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>NC_022442.1|WP_001068497.1|773655_774522_-|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFIYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSTREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFILFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>NC_022442.1|WP_000692521.1|775321_775720_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>NC_022442.1|WP_000855509.1|775682_777788_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYSVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NC_022442.1|WP_000562498.1|777905_778877_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>NC_022442.1|WP_000499195.1|779376_779532_+|hypothetical-protein
MFYFTLSKQNTHSEKLNFSLIANINKIDTKLFERLLKLWSKNATINEKYYQ
>NC_022442.1|WP_000876317.1|779570_780542_+|ABC-transporter-permease
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMEGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_022442_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022442_2

946690-946847

Orphan

Consensus_repeat	Method
CCAACTTGCATTGCTTGTAGAATCTCTTTTCGAAATTCT	PILER-CR
TCTTTTCGAAATTCTCTGTGTTGGGGCCC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_022442_2

>merge|NC_022442|2|946690-946847|PILER-CR,CRISPRCasFinder
AACTTGTATTGCTTGTAGAAATTGGAAATCCAATTGGGGCTCCGCGTCCAACTTGCATTGCTTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCACTCCCCAACTCGCATTGCTTGTAGAATCTCTTTTCGAAATTCTCTGTGTTGGGGCCC

>NC_022442|2|1|946690-946834|PILER-CR
AACTTGTATTGCTTGTAGAAATTGGAAATCCAATTGGGGC	TCCGCGTCCAACTTGCATTGCTTGTAG
AATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCACTCCCC	AACTCGCATTGCTTGTAGA
ATCTCTTTTCGAAATTCTC

>NC_022442|2|2|946761-946847|CRISPRCasFinder
TCTTTTCGAAATTCTCTGTGTTGGGGCCC	ACTCCCCAACTCGCATTGCTTGTAGAATC
TCTTTTCGAAATTCTCTGTGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022442.1\|WP_001047064.1\|952023_952893_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_022442.1\|WP_000404422.1\|954131_954773_+\|L-threonylcarbamoyladenylate-synthase	unknown	unknown	gnl\|CDD\|223088
NC_022442.1\|WP_001124491.1\|944070_945387_-\|CoA-disulfide-reductase	unknown	unknown	gnl\|CDD\|184103
NC_022442.1\|WP_000682089.1\|957384_957570_-\|YjzD-family-protein	unknown	unknown	gnl\|CDD\|371396
NC_022442.1\|WP_000670755.1\|942279_943182_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NC_022442.1\|WP_000902813.1\|943509_943899_+\|YisL-family-protein	unknown	unknown	gnl\|CDD\|237465
NC_022442.1\|WP_001182436.1\|945438_946263_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NC_022442.1\|WP_000007965.1\|933128_933704_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NC_022442.1\|WP_000619354.1\|953002_954148_+\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|223197
NC_022442.1\|WP_001044212.1\|947338_949153_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748
NC_022442.1\|WP_000154915.1\|938460_942114_+\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NC_022442.1\|WP_000758211.1\|933708_934233_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NC_022442.1\|WP_000711897.1\|934248_934824_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NC_022442.1\|WP_001100526.1\|957864_958806_+\|ketoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|236475
NC_022442.1\|WP_000390575.1\|946376_946685_+\|metal-sulfur-cluster-assembly-factor	unknown	unknown	gnl\|CDD\|225062
NC_022442.1\|WP_000695347.1\|955867_956383_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|224793
NC_022442.1\|WP_000769690.1\|956693_957128_+\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
NC_022442.1\|WP_000353962.1\|949355_951965_+\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NC_022442.1\|WP_000081240.1\|958817_960062_+\|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl\|CDD\|274452
NC_022442.1\|WP_000172334.1\|934983_938460_+\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736

Protein	Function_ID	Function_description	E-value
NC_022442.1\|WP_001047064.1\|952023_952893_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.73485e-36
NC_022442.1\|WP_000404422.1\|954131_954773_+\|L-threonylcarbamoyladenylate-synthase	gnl\|CDD\|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	2.09833e-60
NC_022442.1\|WP_001124491.1\|944070_945387_-\|CoA-disulfide-reductase	gnl\|CDD\|184103	PRK13512, PRK13512, coenzyme A disulfide reductase; Provisional.	0
NC_022442.1\|WP_000682089.1\|957384_957570_-\|YjzD-family-protein	gnl\|CDD\|371396	pfam11151, DUF2929, Protein of unknown function (DUF2929). This family of proteins with unknown function appears to be restricted to Firmicutes.	3.19261e-11
NC_022442.1\|WP_000670755.1\|942279_943182_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.74159e-87
NC_022442.1\|WP_000902813.1\|943509_943899_+\|YisL-family-protein	gnl\|CDD\|237465	PRK13673, PRK13673, hypothetical protein; Provisional.	7.45228e-34
NC_022442.1\|WP_001182436.1\|945438_946263_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.66336e-85
NC_022442.1\|WP_000007965.1\|933128_933704_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	2.15479e-40
NC_022442.1\|WP_000619354.1\|953002_954148_+\|2-isopropylmalate-synthase	gnl\|CDD\|223197	COG0119, LeuA, Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism].	1.14533e-101
NC_022442.1\|WP_001044212.1\|947338_949153_+\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	4.03079e-81
NC_022442.1\|WP_000154915.1\|938460_942114_+\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_022442.1\|WP_000758211.1\|933708_934233_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.31712e-49
NC_022442.1\|WP_000711897.1\|934248_934824_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.63465e-53
NC_022442.1\|WP_001100526.1\|957864_958806_+\|ketoacyl-ACP-synthase-III	gnl\|CDD\|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	0
NC_022442.1\|WP_000390575.1\|946376_946685_+\|metal-sulfur-cluster-assembly-factor	gnl\|CDD\|225062	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only].	1.55915e-41
NC_022442.1\|WP_000695347.1\|955867_956383_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	1.3728e-41
NC_022442.1\|WP_000769690.1\|956693_957128_+\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	4.89876e-36
NC_022442.1\|WP_000353962.1\|949355_951965_+\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NC_022442.1\|WP_000081240.1\|958817_960062_+\|beta-ketoacyl-ACP-synthase-II	gnl\|CDD\|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
NC_022442.1\|WP_000172334.1\|934983_938460_+\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0

>NC_022442.1|WP_000390575.1|946376_946685_+|metal-sulfur-cluster-assembly-factor
MEEALKDSILGALEMVIDPELGIDIVNLGLVYKVNVDDEGVCTVDMTLTSMGCPMGPQIIDQVKTVLAEIPEIQDTEVNIVWSPPWTKDMMSRYAKIALGVS
>NC_022442.1|WP_001182436.1|945438_946263_-|Cof-type-HAD-IIB-family-hydrolase
MQPHLICLDLDGTLLNDNKEISSYTKQVLNELQQRGHQIMIATGRPYRASQMYYHELNLTTPIVNFNGAYVHHPKDKNFKTCHEILDLGIAQNIIQGLQQYQVSNIIAEVKDYVFINNHDPRLFEGFSMGNPRIQTGNLLVHLKESPTSILIEAEESKIPEIKNMLTHFYADHIEHRRWGAPFPVIEIVKLGINKARGIEQVRQFLNIDRNNIIAFGDEDNDIEMIEYARHGVAMENGLQELKDVANNITFNNNEDGIGRYLNDFFNLNIRYYC
>NC_022442.1|WP_001124491.1|944070_945387_-|CoA-disulfide-reductase
MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRKYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVSVLNRKTNEQFEESYDKLILSPGASAHSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEIVAINGNEITFKSGRVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK
>NC_022442.1|WP_000902813.1|943509_943899_+|YisL-family-protein
MLHLHILSWVLAIILFIATYLNISKNQGGTPYFKPLHMVLRLFMLLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHTMFWITIALIIITMVLGVILPLGPISKLFGIG
>NC_022442.1|WP_000670755.1|942279_943182_+|fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVERLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
>NC_022442.1|WP_000154915.1|938460_942114_+|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTDWLDQLVTPYEEEAQQAELIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMRRVLEGGFIDIPYLTGHEFGARLPNITAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIHSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQVEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISKVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>NC_022442.1|WP_000172334.1|934983_938460_+|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSMKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDSELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLESFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDALQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFKQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYKDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAATVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGNVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNINIDDEFGGEQ
>NC_022442.1|WP_000711897.1|934248_934824_+|signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKYNFNPENTKN
>NC_022442.1|WP_000758211.1|933708_934233_+|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLVDKKDIIGNISLRYYPFSKWTIQFKS
>NC_022442.1|WP_000007965.1|933128_933704_+|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLIVFWIVGKKLEQHFMGSKKE
>NC_022442.1|WP_001044212.1|947338_949153_+|acetyltransferase
MNKTKGFTKYKKMIYMPGLDGLRAIAVLGIIIYHLNKQWLTGGFLGVDTFFVISGYLITSLLLKEYDDTGIIKLKSFWIRRLKRLLPAVIVLLMVVGTATLLLKSENIIRVKHDIIAAIFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQYYIFFPVILVTLLLTIKKRYKIGFIFWGVSIISLGLMMFIYSINGDHSRVYFGTDTRLQTLLLGVILAFLWPPFKLKNDPPKVVKYIIDSIGSLSFIVLILLFFIINDETNWIYDGGFYLISILTLFIIASVVHPSTWIAKIFSNPVLVFIGKRSYSLYLWHFAVISFVHSYYVDGQIPVYVYFIDISLTIIFAELSYRFIETPFRKEGIKALNWRPSYIPQFIRMAIVVTLLIPFMLILVGAFNKYGKDIIGEKANSFDTTIEDNYLMRIAPIDNIHIDGLVSEKKKESSDVYNNIKPLLIGDSVMVDIGESFKSSVPKSRIDGKVGRQLYQTLPLVKANYSQYKKSSDQVVLELGTNGDFTVKQLDDLLNQFGKAKIYLVNTRVPRIYEANVNRLLADAAKRKSNVTLIDWYKRSQGHSEYFAPDGVHLEYKGVLALKDEILKALKKK
>NC_022442.1|WP_000353962.1|949355_951965_+|ATP-dependent-chaperone-ClpB
MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQYGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEALAKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELDLSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYREYIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATIRTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQGKRAQLDESRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETEREKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSEYMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIMTSNIGSQVLLENVKETGEITEPTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIEVSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE
>NC_022442.1|WP_001047064.1|952023_952893_-|LysR-family-transcriptional-regulator
MNLDWYYTFVILAKTLNYRLASEEINLTIPSIHKQIKNLEQHLNVKLFETYKNQIILTEDGHTFLPIAQSFIEQYESGIKHIQLKKTMFQSKLNVVVSSYIATFIMPKFLKSFFNEHPFIDVSLHVKNENIEKDINNHTYDIGISRNQPKLREVHSEKVCEGKIVLIAPNKENNHLLTEASLFEKYKIISDNHPEYWSSLKNNILNIYEKAQFLSINDVHTSIKLIEMNQGISFLPLYITTNSDYNISVINTKILQAPISFTYIYSKKEIPEILVFIKSFKKYIANEQL
>NC_022442.1|WP_000619354.1|953002_954148_+|2-isopropylmalate-synthase
MIRIQDNTIRDGMQQSNVRKSLFIKKEVLKQINKLNINSVEVGMCTTIEDEFNIHQFRDILSPEKELVVLTRLNEKEIKKIVKLKIHNLVVKILLPISDLHIKEKLNFSNKYYIQKIKDCLEILKKDKKGVDICFEDATRTSREKLKEYMEIISKYQVRTVTFADTVGCSTPLEYGDIFNYFVKKYSNIIFSAHCHNDLGLATANTLAAILNGAKQIETTFLGIGERAGNAPIEEIITILTKKQIESTEFTLPDVYKTSINISKILDFQISENKPIIGENIFKHESGIHQDGTKKNINMYQYLVPSDLGLKNSQVVQFPISNISSKKILHNKFKSIVNTEEIDENISFYKLVNKFSPEVAPEDTVDLLQIIKRRSKDGNFK
>NC_022442.1|WP_000404422.1|954131_954773_+|L-threonylcarbamoyladenylate-synthase
MEILNDSVKSFEKLYLQLQDGFPVIVPTDTNYNLCSLPNNDLCIDKIFEYKKRSKDKPLSLFIDKPEDWKLYGDNQNTEIVDKLVEIFWPGPLNIILKNKTSYNYMLNNSDSIAIGCVQNKTMRRFISYINSPIAITSANISGTADDILITENEAIKHMGENVRYMLRSQNKTNYKTSSTIIKVTDNKIELLREGDIKFEEIKERLGTGIIYE
>NC_022442.1|WP_000695347.1|955867_956383_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MKIKTEFKGNNIPYEYAAGADVSDSINGNPIKSFPFEVTELPEGTKYLAWSLIDYDAIPVCGFAWIHWSVANVSVSGNSISIKADLSRTKGDYVQGKNSFTSGLLAEDFSEIENHYVGPTPPDKDHQYELTVYALGHSLNLKNGFYLNEFLKEVNQHKIDQTSINLIGRKI
>NC_022442.1|WP_000769690.1|956693_957128_+|MAP-domain-containing-protein
MKLKSFITVTLALGMIATTGATVASNEVSAAEKDKLPATQKAKEMQNVPYTIAVDGIMAFNQSYLNLPKDSQLSYLDLGNKVKALLYDERGVTPEKIRNAKSAVYTITWKDGSKKEVDLKKDSYTANLFDSNSIKQIDINVKTK
>NC_022442.1|WP_000682089.1|957384_957570_-|YjzD-family-protein
MKHLVTFFWALLLMQMVNFVLNSLVGGDSLNVVNPIIMAVLFTIFTAIFAAVIKPPKDSSQ
>NC_022442.1|WP_001100526.1|957864_958806_+|ketoacyl-ACP-synthase-III
MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKLKDDDTIVLVGFGGGLTWGAMTIKWGK
>NC_022442.1|WP_000081240.1|958817_960062_+|beta-ketoacyl-ACP-synthase-II
MSQNKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELKNFNIEDHIDKKEARRMDRFTQYAIVAAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGATVTACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSALSIKDSKVAPTIHAVTPDPECDLDIVPNEAQDLDITYAMSNSLGFGGHNAVLVFKKFEA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_022442_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022442_3

1065218-1065310

Orphan

Consensus_repeat	Method
AAAAGCCCCTAACAACTAAAGGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022442_3

>merge|NC_022442|3|1065218-1065310|CRISPRCasFinder
AAAAGCCCCTAACAACTAAAGGTTGTAAGGTAAAAGAGGGATACTTGCGTCGAGCGCAAGCATAAAAGCCCCTAACAACTAAAAGTTGTAAGG

>NC_022442|3|3|1065218-1065310|CRISPRCasFinder
AAAAGCCCCTAACAACTAAAGGTTGTAAGG	TAAAAGAGGGATACTTGCGTCGAGCGCAAGCAT
AAAAGCCCCTAACAACTAAAAGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_022442.1\|WP_000033477.1\|1064160_1064736_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227065
NC_022442.1\|WP_000238670.1\|1058352_1058919_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
NC_022442.1\|WP_000064214.1\|1065319_1065454_-\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000040057.1\|1069516_1071235_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NC_022442.1\|WP_000921971.1\|1062745_1064146_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NC_022442.1\|WP_000483727.1\|1055844_1057329_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
NC_022442.1\|WP_001289624.1\|1071471_1071705_-\|glutaredoxin-like-protein-NrdH	unknown	unknown	gnl\|CDD\|239274
NC_022442.1\|WP_000638454.1\|1073260_1074280_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
NC_022442.1\|WP_000030810.1\|1057321_1058350_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NC_022442.1\|WP_000437472.1\|1069247_1069514_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
NC_022442.1\|WP_000709285.1\|1058933_1060412_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NC_022442.1\|WP_000032747.1\|1053676_1055866_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NC_022442.1\|WP_001101926.1\|1060433_1061681_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
NC_022442.1\|WP_000009075.1\|1065605_1066901_+\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000685063.1\|1067325_1068498_+\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NC_022442.1\|WP_000505962.1\|1068551_1069094_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368297
NC_022442.1\|WP_000514290.1\|1074412_1075075_+\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NC_022442.1\|WP_000381849.1\|1071902_1073264_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NC_022442.1\|WP_000273256.1\|1061946_1062753_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NC_022442.1\|WP_000666799.1\|1053012_1053684_+\|phosphoribosylformylglycinamidine-synthase-I	unknown	unknown	gnl\|CDD\|235140

Protein	Function_ID	Function_description	E-value
NC_022442.1\|WP_000033477.1\|1064160_1064736_-\|ECF-transporter-S-component	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
NC_022442.1\|WP_000238670.1\|1058352_1058919_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	1.52687e-91
NC_022442.1\|WP_000040057.1\|1069516_1071235_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NC_022442.1\|WP_000921971.1\|1062745_1064146_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.91329e-64
NC_022442.1\|WP_000483727.1\|1055844_1057329_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
NC_022442.1\|WP_001289624.1\|1071471_1071705_-\|glutaredoxin-like-protein-NrdH	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	4.9181e-16
NC_022442.1\|WP_000638454.1\|1073260_1074280_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	4.77009e-76
NC_022442.1\|WP_000030810.1\|1057321_1058350_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NC_022442.1\|WP_000437472.1\|1069247_1069514_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
NC_022442.1\|WP_000709285.1\|1058933_1060412_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NC_022442.1\|WP_000032747.1\|1053676_1055866_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NC_022442.1\|WP_001101926.1\|1060433_1061681_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
NC_022442.1\|WP_000685063.1\|1067325_1068498_+\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	2.1836e-146
NC_022442.1\|WP_000505962.1\|1068551_1069094_+\|hypothetical-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00760449
NC_022442.1\|WP_000514290.1\|1074412_1075075_+\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	4.35421e-66
NC_022442.1\|WP_000381849.1\|1071902_1073264_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	2.48829e-165
NC_022442.1\|WP_000273256.1\|1061946_1062753_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	5.49952e-29
NC_022442.1\|WP_000666799.1\|1053012_1053684_+\|phosphoribosylformylglycinamidine-synthase-I	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	1.77638e-140

>NC_022442.1|WP_000033477.1|1064160_1064736_-|ECF-transporter-S-component
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>NC_022442.1|WP_000921971.1|1062745_1064146_-|ABC-transporter-ATP-binding-protein
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQVPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLENVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>NC_022442.1|WP_000273256.1|1061946_1062753_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDVIFIIVLIAIITLAYYCSITLPITGIDDVRLGRVG
>NC_022442.1|WP_001101926.1|1060433_1061681_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSSLVKQVFVIPGNEAMTPIAEVHTEISESDHQGILDFAKQQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGNRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVHDAQRDAYEKVSQIQSDHLFYRHDIANKALQLK
>NC_022442.1|WP_000709285.1|1058933_1060412_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPAAVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTGEALDILKQKKNVRLLEIDMIIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>NC_022442.1|WP_000238670.1|1058352_1058919_+|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNKDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>NC_022442.1|WP_000030810.1|1057321_1058350_+|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDLFLEPTKLYVKPVLTLKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGDIDTNEMYNIFNMGIGYTVIVDEKDASRALKILAEQNVEAYQIGHIVKNESTAIELLGV
>NC_022442.1|WP_000483727.1|1055844_1057329_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSNQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>NC_022442.1|WP_000032747.1|1053676_1055866_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKNYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGVLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>NC_022442.1|WP_000666799.1|1053012_1053684_+|phosphoribosylformylglycinamidine-synthase-I
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
>NC_022442.1|WP_000064214.1|1065319_1065454_-|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>NC_022442.1|WP_000009075.1|1065605_1066901_+|hypothetical-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHYMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>NC_022442.1|WP_000685063.1|1067325_1068498_+|class-I-SAM-dependent-rRNA-methyltransferase
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQEINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSVIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>NC_022442.1|WP_000505962.1|1068551_1069094_+|hypothetical-protein
MGFKNNLTSNLTNKIGNSVFKIENINEKGAMPTTIKELNERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERVMSAAAIQGSQFIGKRISSAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>NC_022442.1|WP_000437472.1|1069247_1069514_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>NC_022442.1|WP_000040057.1|1069516_1071235_+|phosphoenolpyruvate--protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMNGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>NC_022442.1|WP_001289624.1|1071471_1071705_-|glutaredoxin-like-protein-NrdH
MSEIIVYTQNDCPPCTFVKNYLTEHQIVFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>NC_022442.1|WP_000381849.1|1071902_1073264_+|cytochrome-ubiquinol-oxidase-subunit-I
MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>NC_022442.1|WP_000638454.1|1073260_1074280_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFAISFLFFTLASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>NC_022442.1|WP_000514290.1|1074412_1075075_+|TrkA-family-potassium-uptake-protein
MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIATR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_022442_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022442_4

1224107-1224199

Unclear

Consensus_repeat	Method
TAAGAAACAGTAATCAATAAATTGATAACT	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NC_022442_4

>merge|NC_022442|4|1224107-1224199|CRISPRCasFinder
TAAGAAACAGTAATCAATAAATTGATAACTAATAAGCGGAACGCCTGAGCTAAAGCTCATGCATAAGAAACAGTAATCAATAAATTGATAACT

>NC_022442|4|4|1224107-1224199|CRISPRCasFinder
TAAGAAACAGTAATCAATAAATTGATAACT	AATAAGCGGAACGCCTGAGCTAAAGCTCATGCA
TAAGAAACAGTAATCAATAAATTGATAACT

Protein	Signature genes	Signature genes Name	Protein_function
NC_022442.1\|WP_000167269.1\|1223248_1223983_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|235500
NC_022442.1\|WP_000164340.1\|1213981_1214626_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NC_022442.1\|WP_001043838.1\|1222329_1223256_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|223408
NC_022442.1\|WP_000007686.1\|1229081_1230332_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NC_022442.1\|WP_000547905.1\|1214632_1215274_+\|thiamine-diphosphokinase	unknown	unknown	gnl\|CDD\|224480
NC_022442.1\|WP_001261990.1\|1232852_1233356_+\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
NC_022442.1\|WP_000863474.1\|1230676_1232044_+\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NC_022442.1\|WP_000043237.1\|1224637_1225369_+\|ribonuclease-III	unknown	unknown	gnl\|CDD\|234633
NC_022442.1\|WP_000531320.1\|1230318_1230651_+\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
NC_022442.1\|WP_001151491.1\|1218511_1220572_+\|ATP-dependent-DNA-helicase-RecG	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236794
NC_022442.1\|WP_000517908.1\|1215655_1215844_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NC_022442.1\|WP_000268754.1\|1232389_1232665_+\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
NC_022442.1\|WP_000262685.1\|1225515_1229082_+\|chromosome-segregation-protein-SMC	unknown	unknown	gnl\|CDD\|224117
NC_022442.1\|WP_000171418.1\|1216286_1216661_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
NC_022442.1\|WP_000181404.1\|1234195_1234546_+\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NC_022442.1\|WP_000239738.1\|1221350_1222337_+\|phosphate-acyltransferase-PlsX	unknown	unknown	gnl\|CDD\|235414
NC_022442.1\|WP_000687320.1\|1233355_1234093_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
NC_022442.1\|WP_000426914.1\|1224288_1224522_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NC_022442.1\|WP_001548538.1\|1220773_1221346_+\|transcription-factor-FapR	unknown	unknown	gnl\|CDD\|179847
NC_022442.1\|WP_000623917.1\|1216675_1218322_+\|DAK2-domain-containing-protein	unknown	unknown	gnl\|CDD\|224378

Protein	Function_ID	Function_description	E-value
NC_022442.1\|WP_000167269.1\|1223248_1223983_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	3.68137e-140
NC_022442.1\|WP_000164340.1\|1213981_1214626_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	4.67332e-114
NC_022442.1\|WP_001043838.1\|1222329_1223256_+\|ACP-S-malonyltransferase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	9.10665e-134
NC_022442.1\|WP_000007686.1\|1229081_1230332_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
NC_022442.1\|WP_000547905.1\|1214632_1215274_+\|thiamine-diphosphokinase	gnl\|CDD\|224480	COG1564, THI80, Thiamine pyrophosphokinase [Coenzyme metabolism].	1.16343e-81
NC_022442.1\|WP_001261990.1\|1232852_1233356_+\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	7.15666e-69
NC_022442.1\|WP_000863474.1\|1230676_1232044_+\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NC_022442.1\|WP_000043237.1\|1224637_1225369_+\|ribonuclease-III	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	4.78039e-115
NC_022442.1\|WP_000531320.1\|1230318_1230651_+\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	5.84113e-47
NC_022442.1\|WP_001151491.1\|1218511_1220572_+\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NC_022442.1\|WP_000517908.1\|1215655_1215844_-\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	1.3072e-18
NC_022442.1\|WP_000268754.1\|1232389_1232665_+\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	3.01687e-41
NC_022442.1\|WP_000262685.1\|1225515_1229082_+\|chromosome-segregation-protein-SMC	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0
NC_022442.1\|WP_000171418.1\|1216286_1216661_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	4.1554e-37
NC_022442.1\|WP_000181404.1\|1234195_1234546_+\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.77895e-70
NC_022442.1\|WP_000239738.1\|1221350_1222337_+\|phosphate-acyltransferase-PlsX	gnl\|CDD\|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	6.04516e-178
NC_022442.1\|WP_000687320.1\|1233355_1234093_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.74382e-164
NC_022442.1\|WP_000426914.1\|1224288_1224522_+\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
NC_022442.1\|WP_001548538.1\|1220773_1221346_+\|transcription-factor-FapR	gnl\|CDD\|179847	PRK04424, PRK04424, transcription factor FapR.	2.37773e-98
NC_022442.1\|WP_000623917.1\|1216675_1218322_+\|DAK2-domain-containing-protein	gnl\|CDD\|224378	COG1461, COG1461, Predicted kinase related to dihydroxyacetone kinase [General function prediction only].	0

>NC_022442.1|WP_000167269.1|1223248_1223983_+|3-oxoacyl-[acyl-carrier-protein]-reductase
MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>NC_022442.1|WP_001043838.1|1222329_1223256_+|ACP-S-malonyltransferase
MNKTAIIFPGQGAQKVGMAQDLYNNNDQATEILTSAANTLDFDILETMFTDEDGKLGETENTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANINCPGQIVVSGHKALIDELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEVIKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND
>NC_022442.1|WP_000239738.1|1221350_1222337_+|phosphate-acyltransferase-PlsX
MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYKLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNQDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
>NC_022442.1|WP_001548538.1|1220773_1221346_+|transcription-factor-FapR
MRGETLKLKKDKRREAIRQQIDSNPFITDHELSDLFQVSIQTIRLDRTYLNIPELRKRIKLVAEKNYDQISSIEEQEFIGDLIQVNPNVKAQSILDITSDSVFHKTGIARGHVLFAQANSLCVALIKQPTVLTHESSIQFIEKVKLNDTVRAEARVVNQTAKHYYVEVKSYVKHTLVFKGNFKMFYDKRG
>NC_022442.1|WP_001151491.1|1218511_1220572_+|ATP-dependent-DNA-helicase-RecG
MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNKSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQNQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKSSDEAIEIDYDLDQVKSFIDCLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDNVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEIDVLVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD
>NC_022442.1|WP_000623917.1|1216675_1218322_+|DAK2-domain-containing-protein
MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESESEINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAVEKANNTEDCIELMEYIIVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKVEAKVAKLDKDEFVHDEHDFHGVINTEDIIYGYCTEMMVRFGKNKKAFDEQEFRQDMSQFGDSLLVINDEEIVKVHVHTEYPGKVFNYGQQYGELIKLKVENMREQHREVIRKEQHTAKPKMETVETAIITISMGEGISEIFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNILMASEQAASIVDAEAVVIPTKSIPQGISALFQYDVDATLEENKAQMADSVNNVKSGSLTYAVRDTKIDGVEIKKDAFMGLIEDKIVSSQSDQLTTVTELLIEMLAEDSEILTVIIGQDAEQAVTDNMINWIEEQYPDVEVEVHEGGQPIYQYFFSVE
>NC_022442.1|WP_000171418.1|1216286_1216661_+|Asp23/Gls24-family-envelope-stress-response-protein
MTLEISNDYGKIDISNEVIASVVGGKAVECYGIVGMASRQQVRDGIAEILGHENYAKGIKVTENNGVVDIDMYIIVSYGVKISEVANNVQSTVKYTLEKSLNVSVNSINIYVQGVRVNNTGKKA
>NC_022442.1|WP_000517908.1|1215655_1215844_-|50S-ribosomal-protein-L28
MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
>NC_022442.1|WP_000547905.1|1214632_1215274_+|thiamine-diphosphokinase
MHINLLCSDRHLPQDIWAKSNEGKWGGVDRGALILLKHQIIPFFSVGDFDSVSKEERQLLTEQLQIKPVQAEKADTDLALAVDKAVALGFDSITIYGATGGRLDHFFGAIQLLLKKAYYKHDVHIEVIDQQNKIELLPKGQHTVEKDKSYPYISFIPMTDDVELSLAGFKYNLARQMLNIGSTLTISNEIESLQAKVTVHDGLILQIRSTDLN
>NC_022442.1|WP_000164340.1|1213981_1214626_+|ribulose-phosphate-3-epimerase
MTKLYPSLLSVDFLVLQHELKRLEEAGVDGVHFDVMDGQFVPNISIGLPILDAVRKGTTLPIDVHLMIENPEKYIASFAEHGADMISIHVESTPHIHRAIQMIKHLDKKAGVVINPGTPISQIEPILDIVDYVLVMTVNPGFGGQSFIDQCVEKIAGLNAIKMERQLNFDIEVDGGVNTDTAKVCVENGATMLVTGSFFFKQEDYKKVTQALKG
>NC_022442.1|WP_000426914.1|1224288_1224522_+|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
>NC_022442.1|WP_000043237.1|1224637_1225369_+|ribonuclease-III
MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
>NC_022442.1|WP_000262685.1|1225515_1229082_+|chromosome-segregation-protein-SMC
MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVTRRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQIIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLIELLENISNEISEAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSAVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGVKHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFLKERNLGRATFLPLNVIKSRVVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLGNTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTTMRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLTTQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKSSLKRLEDEIERYTKLSKEGKESVTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQSQQTKHQLNDVKEKIAFFNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEATLQVCHQDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKKVKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVTERFKETFHAIQGHFTAVFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLLSGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVITHRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ
>NC_022442.1|WP_000007686.1|1229081_1230332_+|signal-recognition-particle-docking-protein-FtsY
MSFFKRLKDKFATNKENEEVKSLTEEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEEKDDNHGAK
>NC_022442.1|WP_000531320.1|1230318_1230651_+|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE
>NC_022442.1|WP_000863474.1|1230676_1232044_+|signal-recognition-particle-protein
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTKLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIMLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>NC_022442.1|WP_000268754.1|1232389_1232665_+|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
>NC_022442.1|WP_001261990.1|1232852_1233356_+|ribosome-maturation-factor-RimM
MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNNDLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEYYYSDIIGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDVENKKIIITPMEGLLD
>NC_022442.1|WP_000687320.1|1233355_1234093_+|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKIDYLTLFPEMFAGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
>NC_022442.1|WP_000181404.1|1234195_1234546_+|50S-ribosomal-protein-L19
MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_022442_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022442_5

1432165-1432244

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022442_5

>merge|NC_022442|5|1432165-1432244|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGGCTTTCCGCAGCTACTATGTTGGGGACCCGCCAACTTGCACTTTATTGTAAGCTG

>NC_022442|5|5|1432165-1432244|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTG	GCTTTCCGCAGCTACTATGTTGGGGACCCG
CCAACTTGCACTTTATTGTAAGCTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_022442.1\|WP_000166795.1\|1429635_1430991_-\|sensor-histidine-kinase-ArlS	unknown	unknown	gnl\|CDD\|223715
NC_022442.1\|WP_000138424.1\|1417995_1419132_+\|toxic-anion-resistance-protein	unknown	unknown	gnl\|CDD\|377557
NC_022442.1\|WP_000334509.1\|1423877_1424687_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319934
NC_022442.1\|WP_000620194.1\|1434501_1435011_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_022442.1\|WP_000180678.1\|1426548_1429347_-\|2-oxoglutarate-dehydrogenase-E1-component	unknown	unknown	gnl\|CDD\|236499
NC_022442.1\|WP_000160908.1\|1433419_1434490_-\|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	unknown	unknown	gnl\|CDD\|171505
NC_022442.1\|WP_001185421.1\|1422673_1423465_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NC_022442.1\|WP_001283670.1\|1420773_1422660_-\|nitric-oxide-reductase-activation-protein-NorD	unknown	unknown	gnl\|CDD\|226921
NC_022442.1\|WP_000913315.1\|1437825_1438254_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NC_022442.1\|WP_000192137.1\|1430987_1431647_-\|response-regulator-transcription-factor-ArlR	unknown	unknown	gnl\|CDD\|223816
NC_022442.1\|WP_000342123.1\|1435410_1436901_-\|S41-family-peptidase	unknown	unknown	gnl\|CDD\|223864
NC_022442.1\|WP_000801007.1\|1437092_1437314_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226885
NC_022442.1\|WP_000175746.1\|1439723_1440203_-\|dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|365932
NC_022442.1\|WP_000166052.1\|1438869_1439709_-\|fatty-acid-kinase-FakB2	unknown	unknown	gnl\|CDD\|273257
NC_022442.1\|WP_001115452.1\|1425266_1426535_-\|dihydrolipoyllysine-residue-succinyltransferase	unknown	unknown	gnl\|CDD\|235571
NC_022442.1\|WP_001039275.1\|1419205_1420549_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl\|CDD\|224039
NC_022442.1\|WP_000473654.1\|1437313_1437814_-\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225101
NC_022442.1\|WP_000159902.1\|1438246_1438780_-\|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|237269
NC_022442.1\|WP_000902174.1\|1423645_1423849_-\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000084773.1\|1432788_1433403_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486

Protein	Function_ID	Function_description	E-value
NC_022442.1\|WP_000166795.1\|1429635_1430991_-\|sensor-histidine-kinase-ArlS	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.27236e-48
NC_022442.1\|WP_000138424.1\|1417995_1419132_+\|toxic-anion-resistance-protein	gnl\|CDD\|377557	pfam05816, TelA, Toxic anion resistance protein (TelA). This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition.	2.13715e-131
NC_022442.1\|WP_000334509.1\|1423877_1424687_-\|hypothetical-protein	gnl\|CDD\|319934	cd08346, PcpA_N_like, N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. The N-terminal domain of Sphingobium chlorophenolicum (formerly Sphingomonas chlorophenolica) 2,6-dichloro-p-hydroquinone1,2-dioxygenase (PcpA), and similar proteins. PcpA is a key enzyme in the pentachlorophenol (PCP) degradation pathway, catalyzing the conversion of 2,6-dichloro-p-hydroquinone to 2-chloromaleylacetate. This domain belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases.	8.74417e-08
NC_022442.1\|WP_000180678.1\|1426548_1429347_-\|2-oxoglutarate-dehydrogenase-E1-component	gnl\|CDD\|236499	PRK09404, sucA, 2-oxoglutarate dehydrogenase E1 component; Reviewed.	0
NC_022442.1\|WP_000160908.1\|1433419_1434490_-\|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	gnl\|CDD\|171505	PRK12446, PRK12446, undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed.	3.82367e-132
NC_022442.1\|WP_001185421.1\|1422673_1423465_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	4.42262e-45
NC_022442.1\|WP_001283670.1\|1420773_1422660_-\|nitric-oxide-reductase-activation-protein-NorD	gnl\|CDD\|226921	COG4548, NorD, Nitric oxide reductase activation protein [Inorganic ion transport and metabolism].	0
NC_022442.1\|WP_000913315.1\|1437825_1438254_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	9.76591e-81
NC_022442.1\|WP_000192137.1\|1430987_1431647_-\|response-regulator-transcription-factor-ArlR	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.42624e-89
NC_022442.1\|WP_000342123.1\|1435410_1436901_-\|S41-family-peptidase	gnl\|CDD\|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	7.13135e-124
NC_022442.1\|WP_000801007.1\|1437092_1437314_-\|hypothetical-protein	gnl\|CDD\|226885	COG4479, COG4479, Uncharacterized protein conserved in bacteria [Function unknown].	1.53726e-28
NC_022442.1\|WP_000175746.1\|1439723_1440203_-\|dihydrofolate-reductase	gnl\|CDD\|365932	pfam00186, DHFR_1, Dihydrofolate reductase.	8.71869e-81
NC_022442.1\|WP_000166052.1\|1438869_1439709_-\|fatty-acid-kinase-FakB2	gnl\|CDD\|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	8.59745e-119
NC_022442.1\|WP_001115452.1\|1425266_1426535_-\|dihydrolipoyllysine-residue-succinyltransferase	gnl\|CDD\|235571	PRK05704, PRK05704, 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase.	0
NC_022442.1\|WP_001039275.1\|1419205_1420549_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl\|CDD\|224039	COG1114, BrnQ, Branched-chain amino acid permeases [Amino acid transport and metabolism].	1.47543e-160
NC_022442.1\|WP_000473654.1\|1437313_1437814_-\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	9.03019e-68
NC_022442.1\|WP_000159902.1\|1438246_1438780_-\|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl\|CDD\|237269	PRK13014, PRK13014, methionine sulfoxide reductase A; Provisional.	4.15064e-107
NC_022442.1\|WP_000620194.1\|1434501_1435011_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.78214e-09
NC_022442.1\|WP_000084773.1\|1432788_1433403_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	6.60547e-49

>NC_022442.1|WP_000192137.1|1430987_1431647_-|response-regulator-transcription-factor-ArlR
MTQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSHYYDLIILDLMLPSINGLEICRKIRQQQSTPIIIITAKSDTYDKVAGLDYGADDYIVKPFDIEELLARIRAILRRQPQKDIIDVNGITIDKNAFKVTVNGAEIELTKTEYDLLYLLAENKNHVMQREQILNHVWGYNSEVETNVVDVYIRYLRNKLKPYDRDKMIETVRGVGYVIR
>NC_022442.1|WP_000166795.1|1429635_1430991_-|sensor-histidine-kinase-ArlS
MTKRKLRNNWIIVTTMITFVTIFLFCLIIIFFLKDTLHNSELDDAERSSSDINNLFHSKPVKDISALDLNASLGNFQEIIIYDEHNNKLFETSNDNTVRVEPGYEHRYFDRVIKKRYKGIDYLIIKEPITTQDFKGYSLLIHSLENYDNIVKSLYIIALAFGVIATIITATISYVFSTQITKPLVSLSNKMIEIRRDGFQNKLQLNTNYEEIDNLANTFNEMMSQIEESFNQQRQFVEDASHELRTPLQIIQGHLNLIQRWGKKDPAVLEESLNISIEEMNRIIKLVEELLELTKGDVNDISSEAQTVHINDEIRSRIHSLKQLHPDYQFDTDLTSKNLEIKMKPHQFEQLFLIFIDNAIKYDVKNKKIKVKTRLKNKQKIIEITDNGIGIPEEDQDFIFDRFYRVDKSRSRSQGGNGLGLSIAQKIIQLNGGSIKIKSEINKGTTFKIIF
>NC_022442.1|WP_000180678.1|1426548_1429347_-|2-oxoglutarate-dehydrogenase-E1-component
MTNERKEVSEAPVNFGANLGLMLDLYDDFLQDPSSVPEDLQVLFSTIKNDDSIVPALKSTSSQNSDGTIKRVMRLIDNIRQYGHLKADIYPVNPPKRKHVPKLEIEDFDLDQQTLEGISAGIVSDHFADIYDNAYEAILRMEKRYKGPIAFEYTHINNNTERGWLKRRIETPYKVTLNNNEKRALFKQLAYVEGFEKYLHKNFVGAKRFSIEGVDALVPMLQRTITIAAKEGIKNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTDPMKFLPEDGSLQLTAGWTGDVKYHLGGIKTTDSYGTMQRIALANNPSHLEIVAPVVEGRTRAAQDDTQRAGAPTTDHHKAMPIIIHGDAAYPGQGINFETMNLGNLKGYSTGGSLHIITNNRIGFTTEPIDARSTTYSTDVAKGYDVPIFHVNADDVEATIEAIDIAMEFRKEFHKDVVIDLVGYRRFGHNEMDEPSITNPVPYQNIRKHDSVEYVFGKKLVNEGVISEDEMNSFIEQVQKELRQAHDKINKADKMDNPDMEKPADLALPLQADEQSFTFDHLKEINDALLTYPDGFNILKKLNKVLEKRHEPFNKEDGLVDWAQAEQLAFATILQDGTPIRLTGQDSERGTFSHRHAVLHDEQTGETYTPLHHVPDQKATFDIHNSPLSEAAVVGFEYGYNVENKKSFNIWEAQYGDFANMSQMIFDNFLFSSRSKWGERSGLTLFLPHAYEGQGPEHSSARLERFLQLAAENNCTVVNLSSSSNYFHLLRAQAASLDSEQMRPLVVMSPKSLLRNKTVAKPIDEFTSGGFEPILTESYQADKVTKVILATGKMFIDLKEALAKNPDESVLLVAIERLYPFPEEEIEALLAQLPNLEEVSWVQEEPKNQGAWLYVYPYVKVLVADKYDLSYHGRIQRAAPAEGDGEIHKLVQNKIIENALKNN
>NC_022442.1|WP_001115452.1|1425266_1426535_-|dihydrolipoyllysine-residue-succinyltransferase
MPEVKVPELAESITEGTIAEWLKNVGDSVEKGEAILELETDKVNVEVVSEEAGVLSEQLASEGDTVEVGQAIAVIGEGSGNASKENSNDNTPQQNEETNNKKEETTNKSADKAEVNQTTDDNQQRVNATPSARRYARENGVNLAEVSPKTNDLVRKEDIDKKQQAPASTQTTQQAPAKEEKKYNQYPTKPVIREKMSRRKKTAAKKLLEVSNNTAMLTTFNEVDMTNVMELRKRKKDQFMKDHDGTKLGFMSFFTKASVAALKKYPEVNAEIDGDDMITKQYYDIGVAVSTDDGLLVPFVRDCDKKNFAEIEAEIANLAVKAREKKLGLDDMVNGSFTITNGGIFGSMMSTPIINGNQAAILGMHSIITRPIAIDQDTIENRPMMYIALSYDHRIIDGKEAVGFLKTIKELIENPEDLLLES
>NC_022442.1|WP_000334509.1|1423877_1424687_-|hypothetical-protein
MCGLRSITLGTTNIEQTKHFMVDILGLNCEELLENSIRFGDADISPGTRLQFIQVPSEQLEESHFVGIGLRTPTDSGLEEYAEILSSKEIPFTTTKELNGNKYFSFEDNNGHIFSIYSNENNYGVGLGMPSFESAVNPLHQVQGLGPVILKVNHVDITGQILTNIFGLEVFAEYQPFDNADYHVQVFKIGTGGLGGEIHLMPVETEMTMPEYGAVDQVEFETKDADFFNQAKSRLDEVEIPYQTLEQDDIESIRITENSGLSFIFTLQK
>NC_022442.1|WP_000902174.1|1423645_1423849_-|hypothetical-protein
MLHETWKERTPIKKVEVINTDAKKFTVSDMLTVGKQYDVINETEEYYQIIDNSGLIGGYYKTYFKEV
>NC_022442.1|WP_001185421.1|1422673_1423465_-|MoxR-family-ATPase
MALKHYKNSDSTVFNDAKALFDLNKNILLKGPTGSGKTKLAETLSEVVDTPMHQVNCSVDLDTESLLGFKTIKTNAEGQQEIVFVDGPVIKAMKEGHILYIDEINMAKPETLPVLNGVLDYRRQITNPYTGEVIKAVPGFNVIAAINEGYVGTLPMNEALKNRFVVIHVDYIDGDILKNVIKEQSLLQDDKQIEQIIKFNEDLRTMSKQGQISEEAASIRALLDLCDLITVMPVERAIKRTIIDKLEDEREQQAIYNAVELNF
>NC_022442.1|WP_001283670.1|1420773_1422660_-|nitric-oxide-reductase-activation-protein-NorD
MSDRFIKFNDEQLDAKQVMMLQDLARLLLKNEQTQVKIQKFPYYNPVQNVLITSWFWSHRPSHIEMAGLKTDVMLAAYGYHMMDVQIVNEVVQDKTFKHPKFYQQLFKLLEDMRVLNSIKVERPSTAKLIDLRLDTRISYTESQIKVYRTKTQYTDLLFLYLEHAFLSQDFFDIPSIHSDLDDILVNMFLYLPNFFQNQNSEDNMYLAQRIMYQVDDILKEDMLNEYYYLPKTLYNTLASPEFEDLKRTDASQVDGQDDTSEDDDNQSEKADSKSADSESKGGAYLEMELHEGQNSETLGNDEAREGDATDDMTDMMTKKGKGSNDTLNREEGDAVGQSQAFQLDGVNKNVEIKWQIPEIEPQYVLEYQESKQDVQYEIKDLIQIIKKTIEREQRDARFNLTKGRLQKDLINWFIDDQYKLFYKKQDLSKSFDATFTLLIDASASMHDKMAETKKGVVLFHETLKALNIKHEILSFSEDAFDSDEHAQPNIINEIINYDYSTFEKDGPRIMALEPQDDNRDGVAIRVASERLMRRNQHQRFLIVFSDGEPSAFNYSQDGIIDTYEAVEMSRKFGIEVFNVFLSQDPITEDVEQTIHNIYGQYAIFVEGVAHLPGHLSPLLKKLLLKSL
>NC_022442.1|WP_001039275.1|1419205_1420549_-|branched-chain-amino-acid-transport-system-II-carrier-protein
MNKNTWVIGFTLFAMFFGAGNLIFPPNLGLDSGQFFWPAILAFVLTGIGLPLLGVIVGALDKEGYIGALNKISPKFSILFLIIIYLTIGPLFAIPRTASTSFEMTITPIIHSNSSIALFIFTIIYFIVVLYICLNPSKLIDRIGSLLTPLLLITILAMIIKGYLDFSGNSAGKGNEALYHSNFSSFAEGFTQGYLTMDAIAAIAFSMIVVNAVKLTGITKTNQIFKQTLTAGLIAAVALIFIYISLGYIGNHMPVSDMTLDQLKSKDRNIGTYLLTTMASTGFGSFGKYLLGIIVALACLTTACGLIVAVSEYFHRIVPKVSYKAFVLVFILMSFIIANQGLNAVISMSIPVLSIVYPVAITVVLLILIAKFIPTKRISQQIPVIIVFILSIFSVISKLGWLKINFIESLPLRAYSLEWFPVAIIATILGYLVGIFVKQDPIKYQQE
>NC_022442.1|WP_000138424.1|1417995_1419132_+|toxic-anion-resistance-protein
MTENKSFKESHPLDDFISDKELSNTTIQKEKLTIEQQKQVDTISKQINPLDNEGLLAFGSGLQKQMSQFSHQMLDEVQSKDVGPIGDTLSDLMSKLKSVNPNELNTDKPSMLKRIFSRAKSSINEIFSRMQSVSAQVDRITIQLQKHQTHLTRDIELLDTLYDKNKQYFDDLSLHIIAAQQKKLQLENEKLPQLQQQAQQSTNQMDIQQVADMQQFIDRLDKRIYDLQLSRQIALQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMAIALTLMRQRNAVAAQRAVTDTTNDLLTANAEMLKQNAIETATENERGIVDLDTLKRTQRNIIETIEETLIIQQHGREERQLAEKELQQLEQDLKSHLVNIKGPNKQS
>NC_022442.1|WP_000084773.1|1432788_1433403_-|phosphatase-PAP2-family-protein
MSQWKRISLLIVFTLVFGIIAFFHESRLGKWIDNEVYEFIYSSESFITTSIMLGATKVGEVWAMLCISLLLVAYLMLKRHKIEALFFALTMALSGILNPALKNIFDRERPTLLRLIDITGFSFPSGHAMGSTAYFGSGIYLLNRLNQGNSKGILIGLCAAMILLISISRVYLGVHYPTDIIAGIIGGVFCIILSTLLLRNKLIN
>NC_022442.1|WP_000160908.1|1433419_1434490_-|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase
MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFIGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDDQVKKSGYIQYEFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKAIDEEQLTAQILLQELNEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
>NC_022442.1|WP_000620194.1|1434501_1435011_-|GNAT-family-N-acetyltransferase
MIRLGKMSDLDQILNLVEEAKELMKEHDNEQWDDQYPLLEHFEEDIAKDYLYVLEENDKIYGFIVVDQDQAEWYDDIDWPVNREGAFVIHRLTGSKEYKGAATELFNYVIDVVKARGAEVILTDTFALNKPAQGLFAKFGFHKVGEQLMEYPPYDKGEPFYAYYKNLKE
>NC_022442.1|WP_000342123.1|1435410_1436901_-|S41-family-peptidase
MDDKQHKSSSDDERAEIATSNQDQQTNSSKRVHLKRWQFISILIGTILITAVITVVAYIFINQKISGLNKTDQANLNKIENVYKILNSDYFKKQNSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGIITINKFQNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYHKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEKANKHDDVLDKLINILK
>NC_022442.1|WP_000801007.1|1437092_1437314_-|hypothetical-protein
MKNYSFYQFVMTVRGRHDDKGRLAEEIFDDLAFPKHDDDFNILSDYIETHGDFTLPMSVFDDLYEEYTEWLKF
>NC_022442.1|WP_000473654.1|1437313_1437814_-|PTS-glucose-transporter-subunit-IIA
MFKKLFGKGKEVQKDIAIYAPLTGEYVKIEDIPDPVFAQKMMGEGFGINPTEGEVVSPIAGRVDNVFPTKHAIGLKADNGLELLVHIGLDTVQLDGEGFEVLVSSGDEVNVGDPLVRFNLEYINNNAKSVISPIIITNTDQAASINIYDENAVIKGETKVIDVTMN
>NC_022442.1|WP_000913315.1|1437825_1438254_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMLRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK
>NC_022442.1|WP_000159902.1|1438246_1438780_-|peptide-methionine-(S)-S-oxide-reductase-MsrA
MTKEYATLAGGCFWCMVKPFTSYPGIKSVVSGYSGGHVDNPTYEQVCTNQTGHVEAVQITFDPEVTSFENILDIYFKTFDPTDDQGQFFDRGESYQPVIFYHDEHQKKAAEFKKQQLNEQGIFKKPVITPIKPYKNFYPAEDYHQDYYKKNPVHYYQYQRGSGRKAFIESHWGNQNA
>NC_022442.1|WP_000166052.1|1438869_1439709_-|fatty-acid-kinase-FakB2
MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVKTSQPAIGEFISAYEELGKDGAEIISIHLSSGLSGTFNTAYQASQMVDANVTVIDSKSISFGLGYQIQHLVELVKEGVSTSEIVNKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGNLMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSVGVAHANVIEYVDKLKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVVLKK
>NC_022442.1|WP_000175746.1|1439723_1440203_-|dihydrofolate-reductase
MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_022442_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022442_6

1978791-1978872

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACCTGCATT	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NC_022442_6

>merge|NC_022442|6|1978791-1978872|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCATTACCTGTAGAATTTCTTTTTTCGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCATT

>NC_022442|6|6|1978791-1978872|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCATT	ACCTGTAGAATTTCTTTTTTCGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_022442.1\|WP_000949467.1\|1983531_1984032_+\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445
NC_022442.1\|WP_001790257.1\|1980997_1981108_-\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000636142.1\|1977849_1978608_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NC_022442.1\|WP_001790679.1\|1984113_1984206_-\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000613738.1\|1984422_1984977_+\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NC_022442.1\|WP_001017131.1\|1975490_1976534_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NC_022442.1\|WP_000548782.1\|1986360_1986891_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
NC_022442.1\|WP_000180460.1\|1972170_1972371_-\|DUF1128-family-protein	unknown	unknown	gnl\|CDD\|227177
NC_022442.1\|WP_000544973.1\|1981193_1981925_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NC_022442.1\|WP_025174552.1\|1980555_1980969_-\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000228666.1\|1972517_1972982_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NC_022442.1\|WP_000149064.1\|1976530_1977232_-\|cell-wall-active-antibiotics-response-protein	unknown	unknown	gnl\|CDD\|227100
NC_022442.1\|WP_000037087.1\|1973541_1974759_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NC_022442.1\|WP_000153526.1\|1974871_1975501_-\|two-component-system-response-regulator-VraR	unknown	unknown	gnl\|CDD\|225107
NC_022442.1\|WP_078065149.1\|1970911_1972168_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NC_022442.1\|WP_000140176.1\|1985043_1986114_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NC_022442.1\|WP_001110179.1\|1977246_1977633_-\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_001250333.1\|1981926_1983240_-\|lipid-II-isoglutaminyl-synthase-subunit-MurT	unknown	unknown	gnl\|CDD\|223840
NC_022442.1\|WP_000428172.1\|1972988_1973264_+\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000999708.1\|1979136_1980123_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614

Protein	Function_ID	Function_description	E-value
NC_022442.1\|WP_000949467.1\|1983531_1984032_+\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
NC_022442.1\|WP_000613738.1\|1984422_1984977_+\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
NC_022442.1\|WP_000636142.1\|1977849_1978608_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
NC_022442.1\|WP_001017131.1\|1975490_1976534_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
NC_022442.1\|WP_000548782.1\|1986360_1986891_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.50924e-11
NC_022442.1\|WP_000180460.1\|1972170_1972371_-\|DUF1128-family-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.24488e-25
NC_022442.1\|WP_000544973.1\|1981193_1981925_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.79354e-120
NC_022442.1\|WP_000228666.1\|1972517_1972982_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
NC_022442.1\|WP_000149064.1\|1976530_1977232_-\|cell-wall-active-antibiotics-response-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
NC_022442.1\|WP_000037087.1\|1973541_1974759_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	7.61989e-85
NC_022442.1\|WP_078065149.1\|1970911_1972168_-\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NC_022442.1\|WP_000140176.1\|1985043_1986114_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NC_022442.1\|WP_001250333.1\|1981926_1983240_-\|lipid-II-isoglutaminyl-synthase-subunit-MurT	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	2.56502e-98
NC_022442.1\|WP_000153526.1\|1974871_1975501_-\|two-component-system-response-regulator-VraR	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	8.44874e-79
NC_022442.1\|WP_000999708.1\|1979136_1980123_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.82639e-75

>NC_022442.1|WP_000636142.1|1977849_1978608_-|type-I-methionyl-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>NC_022442.1|WP_001110179.1|1977246_1977633_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>NC_022442.1|WP_000149064.1|1976530_1977232_-|cell-wall-active-antibiotics-response-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>NC_022442.1|WP_001017131.1|1975490_1976534_-|sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>NC_022442.1|WP_000153526.1|1974871_1975501_-|two-component-system-response-regulator-VraR
MTIKVLFVDDHEMVRIGISSYLSTQRDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>NC_022442.1|WP_000037087.1|1973541_1974759_+|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKEDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIVFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYAEDTNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>NC_022442.1|WP_000428172.1|1972988_1973264_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>NC_022442.1|WP_000228666.1|1972517_1972982_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>NC_022442.1|WP_000180460.1|1972170_1972371_-|DUF1128-family-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>NC_022442.1|WP_078065149.1|1970911_1972168_-|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIEGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>NC_022442.1|WP_000999708.1|1979136_1980123_+|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYDRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKAHEISGENQIKSHILYEVLMIYRLLDSRYA
>NC_022442.1|WP_025174552.1|1980555_1980969_-|hypothetical-protein
MKPTKVILRDASYVHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEIKFEFALFDSDMDNLKHMEYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVTKSDFNKFINELASLH
>NC_022442.1|WP_001790257.1|1980997_1981108_-|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>NC_022442.1|WP_000544973.1|1981193_1981925_-|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHNFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEKQAKQVLIDRANRQKKSR
>NC_022442.1|WP_001250333.1|1981926_1983240_-|lipid-II-isoglutaminyl-synthase-subunit-MurT
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQAIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>NC_022442.1|WP_000949467.1|1983531_1984032_+|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>NC_022442.1|WP_001790679.1|1984113_1984206_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NC_022442.1|WP_000613738.1|1984422_1984977_+|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NC_022442.1|WP_000140176.1|1985043_1986114_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NC_022442.1|WP_000548782.1|1986360_1986891_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADAYFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_022442_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022442_7

2038562-2038647

Orphan

Consensus_repeat	Method
TGTTGAGGCCCCACCCCAACTTACATTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022442_7

>merge|NC_022442|7|2038562-2038647|CRISPRCasFinder
TGTTGAGGCCCCACCCCAACTTACATTGTTTGTAGAATTTCTTTTCGAAATTCTCTATGTTGGGGCCCCACCCCAACTTACATTGT

>NC_022442|7|7|2038562-2038647|CRISPRCasFinder
TGTTGAGGCCCCACCCCAACTTACATTGT	TTGTAGAATTTCTTTTCGAAATTCTCTA
TGTTGGGGCCCCACCCCAACTTACATTGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_022442.1\|WP_001105712.1\|2047691_2048261_+\|accessory-gene-regulator-AgrB	unknown	unknown	gnl\|CDD\|214819
NC_022442.1\|WP_000206634.1\|2037123_2038347_+\|ArgE/DapE-family-deacylase	unknown	unknown	gnl\|CDD\|181490
NC_022442.1\|WP_000791403.1\|2035632_2036688_-\|bi-component-leukocidin-LukGH-subunit-H	unknown	unknown	gnl\|CDD\|369625
NC_022442.1\|WP_000917289.1\|2042327_2042612_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NC_022442.1\|WP_001068527.1\|2029418_2030705_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181512
NC_022442.1\|WP_001045084.1\|2038787_2040095_+\|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223246
NC_022442.1\|WP_000522383.1\|2044950_2045577_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NC_022442.1\|WP_000681969.1\|2028702_2028879_-\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000239607.1\|2033109_2034102_+\|sphingomyelin-phosphodiesterase	unknown	unknown	gnl\|CDD\|132436
NC_022442.1\|WP_000120338.1\|2043554_2044754_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236768
NC_022442.1\|WP_000595398.1\|2034594_2035611_-\|bi-component-leukocidin-LukGH-subunit-G	unknown	unknown	gnl\|CDD\|369625
NC_022442.1\|WP_025175271.1\|2031284_2032721_-\|extracellular-adherence-protein-Eap/Map	unknown	unknown	gnl\|CDD\|367591
NC_022442.1\|WP_000691584.1\|2027781_2028162_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NC_022442.1\|WP_001093929.1\|2048257_2048398_+\|cyclic-lactone-autoinducer-peptide	unknown	unknown	gnl\|CDD\|368676
NC_022442.1\|WP_001823225.1\|2047321_2047456_-\|delta-lysin-family-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|173213
NC_022442.1\|WP_000197629.1\|2042786_2043530_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NC_022442.1\|WP_000990056.1\|2029120_2029219_-\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_001823710.1\|2030983_2031274_-\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
NC_022442.1\|WP_000240638.1\|2040635_2042252_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NC_022442.1\|WP_000867953.1\|2045937_2046723_+\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607

Protein	Function_ID	Function_description	E-value
NC_022442.1\|WP_001105712.1\|2047691_2048261_+\|accessory-gene-regulator-AgrB	gnl\|CDD\|214819	smart00793, AgrB, Accessory gene regulator B. The accessory gene regulator (agr) of Staphylococcus aureus is the central regulatory system that controls the gene expression for a large set of virulence factors. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. At low cell density, the agr genes are continuously expressed at basal levels. A signal molecule, autoinducing peptide (AIP), produced and secreted by the bacteria, accumulates outside of the cells. When the cell density increases and the AIP concentration reaches a threshold, it activates the agr response, i.e. activation of secreted protein gene expression and subsequent repression of cell wall-associated protein genes. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein. AgrB is involved in the proteolytic processing of AgrD and may have both proteolytic enzyme activity and a transporter facilitating the export of the processed AgrD peptide.	1.73876e-47
NC_022442.1\|WP_000206634.1\|2037123_2038347_+\|ArgE/DapE-family-deacylase	gnl\|CDD\|181490	PRK08588, PRK08588, succinyl-diaminopimelate desuccinylase; Reviewed.	0
NC_022442.1\|WP_000791403.1\|2035632_2036688_-\|bi-component-leukocidin-LukGH-subunit-H	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.0236e-77
NC_022442.1\|WP_000917289.1\|2042327_2042612_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
NC_022442.1\|WP_001068527.1\|2029418_2030705_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181512	PRK08637, PRK08637, hypothetical protein; Provisional.	0
NC_022442.1\|WP_001045084.1\|2038787_2040095_+\|TrkH-family-potassium-uptake-protein	gnl\|CDD\|223246	COG0168, TrkG, Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.39244e-80
NC_022442.1\|WP_000522383.1\|2044950_2045577_+\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	4.41942e-115
NC_022442.1\|WP_000120338.1\|2043554_2044754_-\|hypothetical-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	1.18035e-10
NC_022442.1\|WP_000239607.1\|2033109_2034102_+\|sphingomyelin-phosphodiesterase	gnl\|CDD\|132436	TIGR03395, Sphingomyelinase_C, sphingomyelin phosphodiesterase. Members of this family are bacterial proteins that act as sphingomyelin phosphodiesterase (EC 3.1.4.12), also called sphingomyelinase. Some members of this family have been shown to act as hemolysins. [Cellular processes, Pathogenesis].	2.38027e-136
NC_022442.1\|WP_000595398.1\|2034594_2035611_-\|bi-component-leukocidin-LukGH-subunit-G	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	2.97231e-99
NC_022442.1\|WP_025175271.1\|2031284_2032721_-\|extracellular-adherence-protein-Eap/Map	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	1.9425e-33
NC_022442.1\|WP_000691584.1\|2027781_2028162_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	7.00479e-47
NC_022442.1\|WP_001093929.1\|2048257_2048398_+\|cyclic-lactone-autoinducer-peptide	gnl\|CDD\|368676	pfam05931, AgrD, Staphylococcal AgrD protein. This family consists of several AgrD proteins from many Staphylococcus species. The agr locus was initially described in Staphylococcus aureus as an element controlling the production of exoproteins implicated in virulence. Its pattern of action has been shown to be complex, upregulating certain extracellular toxins and enzymes expressed post-exponentially and repressing some exponential-phase surface components. AgrD encodes the precursor of the autoinducing peptide (AIP).The AIP derived from AgrD by the action of AgrB interacts with AgrC in the membrane to activate AgrA, which upregulates transcription both from promoter P2, amplifying the response, and from P3, initiating the production of a novel effector: RNAIII. In S. aureus, delta-hemolysin is the only translation product of RNA III and is not involved in the regulatory functions of the transcript, which is therefore the primary agent for modulating the expression of other operons controlled by agr.	4.80574e-21
NC_022442.1\|WP_001823225.1\|2047321_2047456_-\|delta-lysin-family-phenol-soluble-modulin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	4.75617e-14
NC_022442.1\|WP_000197629.1\|2042786_2043530_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	2.12966e-11
NC_022442.1\|WP_001823710.1\|2030983_2031274_-\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	3.03704e-31
NC_022442.1\|WP_000240638.1\|2040635_2042252_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NC_022442.1\|WP_000867953.1\|2045937_2046723_+\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	2.11308e-126

>NC_022442.1|WP_000206634.1|2037123_2038347_+|ArgE/DapE-family-deacylase
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKNGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLEDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINNVDSNKLSLDIPSNHRPVTSDKNNKLITTIKDVASSYVDKDDIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK
>NC_022442.1|WP_000791403.1|2035632_2036688_-|bi-component-leukocidin-LukGH-subunit-H
MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSPVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
>NC_022442.1|WP_000595398.1|2034594_2035611_-|bi-component-leukocidin-LukGH-subunit-G
MIKQLYKNITICSLAISTVLTVFPATSYAKINSEIKAVSEKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGGLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDEGKSKFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHDVKFVKVLNDNEKK
>NC_022442.1|WP_000239607.1|2033109_2034102_+|sphingomyelin-phosphodiesterase
MVKKTKSNSLKKVATLALANLLLVGALTDNSAKAESKKDDTDLKLVSHNVYMLSTVLYPNWGQYKRADLIGQSSYIKNNDVVIFNEAFDNGASDKLLSNVKKEYPYQTPVLGRSQSGWDKTEGSYSSTVAEDGGVAIVSKYPIKEKIQHVFKSGCGFDNDSNKGFVYTKIEKNGKNVHVIGTHTQSEDSRCGAGHDRKIRAEQMKEISDFVKKKNIPKDETVYIGGDLNVNKGTPEFKDMLKNLNVNDVLYAGHNSTWDPQSNSIAKYNYPNGKPEHLDYIFTDKDHKQPKQLVNEVVTEKPKPWDVYAFPYYYVYNDFSDHYPIKAYSK
>NC_022442.1|WP_025175271.1|2031284_2032721_-|extracellular-adherence-protein-Eap/Map
MKFKSLITTTLALGVLASTGANFNNNEASAGAKPLDKSSSSLHHGYSKVHVPYAITVNGTSQNILSSLTFNKNQNISYKDLEDRVKSVLKSDRGISDIDLRLSKQAEYTVYFKNGAKRVIDLKAGIYTADLINTSEIKAININVDTKKHIEDKKKDKANYQVPYTITVNGTSQNILSNLTFNKNQNISYKDLEDKVKSVLESNRGITDVDLRLSKQAKYTVNFKNGTKKVIDLKAGIYTANLINSSDIKSININVDTKKHVENKAKRNYQVPYSINLNGTSTNILSNLSFSNKPWKNYKDLTRQIKSVLKHDRGISEQDLKYAKKAYYTVYFKNGGKRILQLNSKNYTANLVHAKDVKRIEITVKTGPKAKADRYVPYTIAVNGTSTPILSKLKFSGDPRVGYSDITKKVKSVLKYDRGISDRELKFAKKATYTLHFKNGKKQVVNLNSNIFTPNLFSAKDIKKIDINVKQHTKSKKK
>NC_022442.1|WP_001823710.1|2030983_2031274_-|MAP-domain-containing-protein
MKFPVTINKFENIVSNEFVFYNASKITINDLSIKLKSAMANDQGITKHDIGLAERAVYKVYFKNGSSKYVDLKTEYKDGKVFKATDIKKVDIELKF
>NC_022442.1|WP_001068527.1|2029418_2030705_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MNPLAQSLNEQLQQSNATAFAMLSDLGQNMFYPKGILSQSAEAKSTTYNATIGMATNKDGKMFASSLDAMFNDLTPDEIFPYAPPQGIEELRDLWQQKMLRDNPELSIDNMSRPIVTNALTHGLSLVGDLFVNQDDTILLPEHNWGNYKLVFNTRNGANLQTYPIFDKDGHYTTDSLVEALQSYNKDKVIMILNYPNNPTGYTPTHEEVTTIVNAIKALADKGTKVIAVVDDAYYGLFYEDVYTQSLFTALSNLNSNAILPVRLDGATKEFFAWGFRVGFMTFGTSDQTTKEVLEAKVKGLIRSNISSGPLPTQSAVKHVLKNNKQFDKEIEQNIQTLKERYEVTKEVVYADQYHSHWQAYDFNSGYFMAIKVHDVDPEELRKHLIEKYSIGVIALNATDIRIAFSCVEKEDIPHVFDSIAKAIDDLR
>NC_022442.1|WP_000990056.1|2029120_2029219_-|hypothetical-protein
MMWWQEGMMTLITGGLLIIFRLWLELKWKNKK
>NC_022442.1|WP_000681969.1|2028702_2028879_-|hypothetical-protein
MKHLTKIFVVLAIILFIVGYYLQATNHESQGIKLLLAAIMFMICAFISRSNDRRKNNK
>NC_022442.1|WP_000691584.1|2027781_2028162_-|GntR-family-transcriptional-regulator
MKIILKNNSDFPIYEQIKQQVKQNILKGHVAPGEHLPSMRELAKDLQVSLITTKRAYEDLEKDGFVTTIRGKGTFVKEQDSSILKEKQFFTIENLVKELVNEAQAIEMSLEELQDILTFIYEEESS
>NC_022442.1|WP_001045084.1|2038787_2040095_+|TrkH-family-potassium-uptake-protein
MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNRFLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSSDPIVIITTSILIIFGGIGHFVVIDFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQNMGLVEKIGNSFFQSVTTRTAGFNSIDIAIINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKENNVSVFNKEISDKHIKLSIVTINISFLFISIITFILSIINPNISLIKLLFEVVSAFGTVGLSMNLTTEYHGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRYTKGQIYL
>NC_022442.1|WP_000240638.1|2040635_2042252_-|chaperonin-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNIYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>NC_022442.1|WP_000917289.1|2042327_2042612_-|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NC_022442.1|WP_000197629.1|2042786_2043530_+|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEHKKYIIPWALLGFALVMIYQMVVSIVYTQIFGTQQTSPNTERLIVIARKIPLFIFFVSIVGPLLEEYVFRKVIFGELFNAIKGNRIVAFAIATTVSSLIFALAHNDYKFIPIYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>NC_022442.1|WP_000120338.1|2043554_2044754_-|hypothetical-protein
MSYHWFTKMLLSTSILILSSSSLGLATDTVEAKDNLNGEKPTTNLNHNVTSPSVNSEINNNETGTPPESNQTGNEGTDSNSRDANPDSNNVKPDSNNQNPSPDSKPDPNNPNPVPNPKPDPDKPKPNPEPKPDPDNPKPKPDPKPDPKPDPDNPKPKPDPKPDPDKPKPNPNPSPDPNQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>NC_022442.1|WP_000522383.1|2044950_2045577_+|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKSFNPVEDRFVIKK
>NC_022442.1|WP_000867953.1|2045937_2046723_+|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNETQITQWFEKNMNDEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNNQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>NC_022442.1|WP_001823225.1|2047321_2047456_-|delta-lysin-family-phenol-soluble-modulin
MSCLILRIFILIKEGVISMAQDIISTISDLVKWIIDTVNKFTKK
>NC_022442.1|WP_001105712.1|2047691_2048261_+|accessory-gene-regulator-AgrB
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTLAYILNIFLFTLITNLTFYLIRRHAHGAHAPSSFWCYVESILLFILLPLVILNFHINPLIMIILTVISLGVISVYAPAATKKKPIPVRLIKRKKYYAIIVSLTFFIITLIIKEPFAQFIQLGIIIEAITLLPIFFIKEDLK
>NC_022442.1|WP_001093929.1|2048257_2048398_+|cyclic-lactone-autoinducer-peptide
MNTLFNLFFDFITGILKNIGNIAAYSTCDFIMDEVEVPKELTQLHE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_022442_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022442_8

2286145-2286229

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTATGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022442_8

>merge|NC_022442|8|2286145-2286229|CRISPRCasFinder
CCAACTTGCACATTATTGTATGCTGACTTTTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NC_022442|8|8|2286145-2286229|CRISPRCasFinder
CCAACTTGCACATTATTGTATGCTGACTTT	TGTCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_022442.1\|WP_001161085.1\|2277061_2277379_+\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000503820.1\|2291053_2291560_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NC_022442.1\|WP_000808500.1\|2288293_2288740_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NC_022442.1\|WP_000643988.1\|2287448_2288048_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NC_022442.1\|WP_031844963.1\|2282503_2282755_+\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_031844964.1\|2285895_2286066_+\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000592328.1\|2277565_2280733_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NC_022442.1\|WP_000184418.1\|2284106_2285318_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NC_022442.1\|WP_000866974.1\|2288054_2288288_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NC_022442.1\|WP_000259720.1\|2289235_2290495_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NC_022442.1\|WP_000413855.1\|2280849_2282115_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NC_022442.1\|WP_001824308.1\|2286406_2287429_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NC_022442.1\|WP_000066900.1\|2285419_2285770_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NC_022442.1\|WP_000051210.1\|2276652_2276817_+\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000951066.1\|2283673_2284114_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NC_022442.1\|WP_000600972.1\|2282746_2283511_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NC_022442.1\|WP_000076924.1\|2291590_2292595_-\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
NC_022442.1\|WP_000913006.1\|2292763_2293369_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NC_022442.1\|WP_000602934.1\|2288753_2289239_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NC_022442.1\|WP_000134534.1\|2290557_2291052_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483

Protein	Function_ID	Function_description	E-value
NC_022442.1\|WP_000503820.1\|2291053_2291560_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	9.7838e-65
NC_022442.1\|WP_000808500.1\|2288293_2288740_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NC_022442.1\|WP_000643988.1\|2287448_2288048_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NC_022442.1\|WP_000866974.1\|2288054_2288288_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	1.33137e-25
NC_022442.1\|WP_000592328.1\|2277565_2280733_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_022442.1\|WP_000184418.1\|2284106_2285318_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.58324e-72
NC_022442.1\|WP_000913006.1\|2292763_2293369_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.03488e-114
NC_022442.1\|WP_000259720.1\|2289235_2290495_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	6.25944e-158
NC_022442.1\|WP_000600972.1\|2282746_2283511_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	2.21672e-37
NC_022442.1\|WP_001824308.1\|2286406_2287429_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.93513e-164
NC_022442.1\|WP_000066900.1\|2285419_2285770_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NC_022442.1\|WP_000951066.1\|2283673_2284114_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.06862e-14
NC_022442.1\|WP_000413855.1\|2280849_2282115_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	8.95714e-143
NC_022442.1\|WP_000076924.1\|2291590_2292595_-\|ThiF-family-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	1.97231e-131
NC_022442.1\|WP_000602934.1\|2288753_2289239_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	1.17898e-50
NC_022442.1\|WP_000134534.1\|2290557_2291052_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	2.70933e-97

>NC_022442.1|WP_031844964.1|2285895_2286066_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNDMECDINVKEPLKIYYVVILKSGIEMIFS
>NC_022442.1|WP_000066900.1|2285419_2285770_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NC_022442.1|WP_000184418.1|2284106_2285318_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDRSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAINLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NC_022442.1|WP_000951066.1|2283673_2284114_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKYQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NC_022442.1|WP_000600972.1|2282746_2283511_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIETVKNKLQSEQVEVVGPIQMERDTHKDGKAKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NC_022442.1|WP_031844963.1|2282503_2282755_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNTLTILSIVLAIIHMGILAHSTYVYLY
>NC_022442.1|WP_000413855.1|2280849_2282115_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NC_022442.1|WP_000592328.1|2277565_2280733_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSVQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLMPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASASNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGGNLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQYQEGLGVVSTTYKKALHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATMVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NC_022442.1|WP_001161085.1|2277061_2277379_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NC_022442.1|WP_000051210.1|2276652_2276817_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NC_022442.1|WP_001824308.1|2286406_2287429_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLNVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEEHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NC_022442.1|WP_000643988.1|2287448_2288048_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NC_022442.1|WP_000866974.1|2288054_2288288_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQGLTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NC_022442.1|WP_000808500.1|2288293_2288740_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NC_022442.1|WP_000602934.1|2288753_2289239_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRDEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NC_022442.1|WP_000259720.1|2289235_2290495_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKTVKAKVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NC_022442.1|WP_000134534.1|2290557_2291052_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
>NC_022442.1|WP_000503820.1|2291053_2291560_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NC_022442.1|WP_000076924.1|2291590_2292595_-|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSACTTCGDIPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NC_022442.1|WP_000913006.1|2292763_2293369_-|ATP-binding-cassette-domain-containing-protein
MLKINLKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_022442_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022442_9

2440711-2440803

Orphan

Consensus_repeat	Method
TTCTTCAAATTTATTTGTTAGAAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022442_9

>merge|NC_022442|9|2440711-2440803|CRISPRCasFinder
TTCTTCAAATTTATTTGTTAGAAAGGCTTATGCAGTTGACGTTTTACGTCCTACTACGTTCCTTTGTCTTCTTCAAATTTATTTGTTAGAAAG

>NC_022442|9|9|2440711-2440803|CRISPRCasFinder
TTCTTCAAATTTATTTGTTAGAAAG	GCTTATGCAGTTGACGTTTTACGTCCTACTACGTTCCTTTGTC
TTCTTCAAATTTATTTGTTAGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_022442.1\|WP_001046638.1\|2448748_2449756_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NC_022442.1\|WP_001125208.1\|2438622_2439309_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|184518
NC_022442.1\|WP_000819839.1\|2432459_2432822_-\|DUF4467-domain-containing-protein	unknown	unknown	gnl\|CDD\|291399
NC_022442.1\|WP_000783428.1\|2445445_2446423_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	unknown	unknown	gnl\|CDD\|273388
NC_022442.1\|WP_000594519.1\|2442999_2443929_+\|bi-component-gamma-hemolysin-HlgAB-subunit-A	unknown	unknown	gnl\|CDD\|369625
NC_022442.1\|WP_014532694.1\|2441007_2441103_-\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000971541.1\|2447655_2448771_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223234
NC_022442.1\|WP_000916705.1\|2444496_2445444_+\|bi-component-gamma-hemolysin-HlgCB-subunit-C	unknown	unknown	gnl\|CDD\|369625
NC_022442.1\|WP_000162810.1\|2431841_2432441_-\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|224565
NC_022442.1\|WP_000762708.1\|2438364_2438469_+\|putative-metal-homeostasis-protein	unknown	unknown	unknown
NC_022442.1\|WP_000825921.1\|2435851_2436631_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270429
NC_022442.1\|WP_000286874.1\|2446952_2447645_-\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
NC_022442.1\|WP_001012236.1\|2433076_2434327_+\|FemA/FemB-family-glycyltransferase-FmhA	unknown	unknown	gnl\|CDD\|367067
NC_022442.1\|WP_000038954.1\|2436751_2438191_-\|multidrug-efflux-MFS-transporter-MdeA	unknown	unknown	gnl\|CDD\|129794
NC_022442.1\|WP_001110080.1\|2449757_2451116_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
NC_022442.1\|WP_000200957.1\|2446474_2446942_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377623
NC_022442.1\|WP_000792557.1\|2441197_2442508_+\|B-domain-containing-protein	unknown	unknown	gnl\|CDD\|288473
NC_022442.1\|WP_000479576.1\|2435151_2435871_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NC_022442.1\|WP_000615464.1\|2434423_2435155_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NC_022442.1\|WP_000019124.1\|2439634_2440501_-\|cation-transporter	unknown	unknown	gnl\|CDD\|223131

Protein	Function_ID	Function_description	E-value
NC_022442.1\|WP_001125208.1\|2438622_2439309_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|184518	PRK14119, gpmA, phosphoglyceromutase; Provisional.	3.52864e-167
NC_022442.1\|WP_000792557.1\|2441197_2442508_+\|B-domain-containing-protein	gnl\|CDD\|288473	pfam11621, Sbi-IV, C3 binding domain 4 of IgG-bind protein SBI. This family of proteins represents Sbi domain IV which binds the central complement protein C3. Sbi-IV interacts with Sbi-III to induce a consumption of complement via alternative pathway activation. When not interacting with Sbi-III, Sbi-IV inhibits the alternative pathway without complement consumption. The structure of Sbi-IV consists of a three-helix bundle fold.	1.40953e-27
NC_022442.1\|WP_000783428.1\|2445445_2446423_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	5.50766e-128
NC_022442.1\|WP_000162810.1\|2431841_2432441_-\|DsbA-family-protein	gnl\|CDD\|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	1.74649e-30
NC_022442.1\|WP_000819839.1\|2432459_2432822_-\|DUF4467-domain-containing-protein	gnl\|CDD\|291399	pfam14729, DUF4467, Domain of unknown function with cystatin-like fold (DUF4467). Large family of predicted lipoproteins from Gram-positive bacteria Experimentally determined structure shows a cystatitin-like fold, allowing us to classify this family in the NFT2 clan, despite lack of any detectable sequence similarity between members of this family and other families in this clan.	2.57351e-31
NC_022442.1\|WP_000971541.1\|2447655_2448771_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	8.76662e-139
NC_022442.1\|WP_000916705.1\|2444496_2445444_+\|bi-component-gamma-hemolysin-HlgCB-subunit-C	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	8.96448e-91
NC_022442.1\|WP_000594519.1\|2442999_2443929_+\|bi-component-gamma-hemolysin-HlgAB-subunit-A	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	4.31899e-97
NC_022442.1\|WP_001046638.1\|2448748_2449756_-\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NC_022442.1\|WP_000825921.1\|2435851_2436631_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270429	cd13711, PBP2_Ngo0372_TcyA, Substrate binding domain of ABC transporters involved in cystine import; the type 2 periplasmic binding protein fold. This subgroup includes cystine-binding domain of periplasmic receptor-dependent ATP-binding cassette transporters from Neisseria gonorrhoeae and Bacillus subtilis and their related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.11829e-100
NC_022442.1\|WP_000286874.1\|2446952_2447645_-\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	3.38132e-130
NC_022442.1\|WP_001012236.1\|2433076_2434327_+\|FemA/FemB-family-glycyltransferase-FmhA	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
NC_022442.1\|WP_000038954.1\|2436751_2438191_-\|multidrug-efflux-MFS-transporter-MdeA	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.87495e-92
NC_022442.1\|WP_001110080.1\|2449757_2451116_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
NC_022442.1\|WP_000200957.1\|2446474_2446942_-\|hypothetical-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00179425
NC_022442.1\|WP_000479576.1\|2435151_2435871_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.98247e-78
NC_022442.1\|WP_000615464.1\|2434423_2435155_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.36888e-142
NC_022442.1\|WP_000019124.1\|2439634_2440501_-\|cation-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	6.59628e-89

>NC_022442.1|WP_000019124.1|2439634_2440501_-|cation-transporter
MSHNENLKLAQRGAYLSLIVYIILSIVKYVTGFVFNSAAVRADALNNMTDIIVSLAVIIGLKISIKPADRNHPYGHLKSENISSLLVSFVIMFVGIQVVIQNAPRLFKEDDVVPNAITIIVSLISGLIMLIVFAVNQSLAKRTKSSSLNSAAKDNLSDSLVSIGTAIGLIFTQIGFPIVDIILATLLGLLIVYTGFGIFKEAIFMLSDGFNETELEAYRNDILEVDEVQKVKSIKGRYHGSSVFIDVTIVVDANLSLVEAHQICDNVEHHLHKKGISSVYVHPEPDHL
>NC_022442.1|WP_001125208.1|2438622_2439309_-|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
>NC_022442.1|WP_000762708.1|2438364_2438469_+|putative-metal-homeostasis-protein
MKLDLQTARRNLNSPNIKTRKRALKIIKQHKRAK
>NC_022442.1|WP_000038954.1|2436751_2438191_-|multidrug-efflux-MFS-transporter-MdeA
MSKKQKLTMIITMLMGGFFGLLNETLLVTALPSIMKDFEISYTQVQWLTTAFLLTNGIVIPLSALVIQRYTTRQVFLVGISIFFLGTLLGGLSPHFATLLVARIIQALGAGIMMPLMMTTILDVFQPHERGKYMGIFGLVIGLAPAIGPTLSGYLVEYFNWRSLFHVVAPIAAVTFLIGFKTIKNVGTTIKVPIDFISVIFSVLGFGGLLYGTSSISEKGFDNPIVLVSMIGGIVLVALFVLRQYRLSTPLLNFAVFKNKQFTVGIIIMGVTMVSMIGSETILPIFVQNLLHRSALDSGLTLLPGAIVMAFMSMTSGALYEKFGPRKLALVGMAIVVITTAYFVVMDEQTSTIMLATVYAIRMVGIALGLIPVMTHTMNQLKPEMNAHGSSMTNTVQQIAGSIGTAALITILAHASKNFSPTMSDYNGMNKIDMMNQIKVDTMLHGYHAGFLFALLITVVSFFCSFMLQGKKKEVDSRQ
>NC_022442.1|WP_000825921.1|2435851_2436631_-|transporter-substrate-binding-domain-containing-protein
MKRLLFVMIAFVFILAACGNNSSKDKEANKDSKTINVGTEGTYAPFSFHDKDGKLTGYDIDVIKAVAKEEGLKLKFNETSWDSMFAGLDAGRFDVIANQVGINPDREKKYKFSKPYTFSSAVLVIRENEKDIKDFDDVKGKKLAQTFTSNYGKLAKDKGADITKVDGFNQSMDLLLSKRVDGTFNDSLSYLDYKKQKPNAKIKAIKGNAEQSRSAFAFSKKADDETVQKFNDGLKKIEENGELAKIGKKWFGQDVSKSK
>NC_022442.1|WP_000479576.1|2435151_2435871_-|amino-acid-ABC-transporter-permease
MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
>NC_022442.1|WP_000615464.1|2434423_2435155_-|amino-acid-ABC-transporter-ATP-binding-protein
MIQLNNIHKSFNDVEVIKGIDLSVEQGEVVTLIGRSGSGKTTLLRMINALEIPTEGTVYVNGKTYTSKDKKSQIEVRKQSGMVFQSYNLFPHKTALENVMEGLITVKKLKKDEARGKSLELLEKVGLTLVKDQRPHALSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVNDVLKVIKDLANEGMTMVIVTHEMRFAKEVSNNIVFIHEGMIGEQGAPEEMFNRPKTEELRRFLNVINEE
>NC_022442.1|WP_001012236.1|2433076_2434327_+|FemA/FemB-family-glycyltransferase-FmhA
MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKQNCLYVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDTLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALEENPNSKKNKTKRTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRYNFYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYKVQTYLNHKRR
>NC_022442.1|WP_000819839.1|2432459_2432822_-|DUF4467-domain-containing-protein
MKRFVAMVLLLLVFISGCGNDKYVKEIDEAVKIQNQKQEQLAKKGNGDRVDHFERKDANIYVYDKDKIIILAYKPLSNDDEVHYYAYDFSDKRVSYKQDFDSRRYYQQHDADYHEENMTN
>NC_022442.1|WP_000162810.1|2431841_2432441_-|DsbA-family-protein
MTKKLLTLFIVSMLILTACGKKESATTSSKNGKPLVVIYGDYKCPYCKELDEKVMPKLRKNYIDNHKVEYQFVNLAFLGKDSIVGSRASHAVLMYAPKSFLDFQKQLFAAQQDENKEWLTKELLDKHIKQLHLDKETENKIIKDYKTKDSKSWKAAEKDKKIAKDNHIKTTPTAFINGEKVEDPYDYESYEKLLKDKIK
>NC_022442.1|WP_014532694.1|2441007_2441103_-|hypothetical-protein
MLTNRLTSVNYVKKRLIQNIQRILSKEVLYG
>NC_022442.1|WP_000792557.1|2441197_2442508_+|B-domain-containing-protein
MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAISKLNEKDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYTDKYFKYKGTIDKTVLSVFGNGYKSYIQPLKVEDQKNYVSKSYAQVRNYVTETLNTGKVLYAFYQNPNVVKAAITTAETAASIKNIFSSFTSFFK
>NC_022442.1|WP_000594519.1|2442999_2443929_+|bi-component-gamma-hemolysin-HlgAB-subunit-A
MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK
>NC_022442.1|WP_000916705.1|2444496_2445444_+|bi-component-gamma-hemolysin-HlgCB-subunit-C
MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKNTNHIKSMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSDLPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRIHNAFVNRNYTVKYEVNWKTHEIKVKGQN
>NC_022442.1|WP_000783428.1|2445445_2446423_+|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
>NC_022442.1|WP_000200957.1|2446474_2446942_-|hypothetical-protein
MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPVALLILAFFGIKKYFLGGLLSSVLLLIFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLILASVLGSLISRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR
>NC_022442.1|WP_000286874.1|2446952_2447645_-|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYIKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFLESTPKQVVYETV
>NC_022442.1|WP_000971541.1|2447655_2448771_-|pyridoxal-phosphate-dependent-aminotransferase-family-protein
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLAECPNQNIQKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGVDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDVDRLFEILHQED
>NC_022442.1|WP_001046638.1|2448748_2449756_-|biotin-synthase-BioB
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKEKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
>NC_022442.1|WP_001110080.1|2449757_2451116_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEEAIVIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEMMAAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYDAFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKRKLLSQIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRNCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDRKC

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_022442_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022442_10

2783260-2783345

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022442_10

>merge|NC_022442|10|2783260-2783345|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NC_022442|10|10|2783260-2783345|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_022442.1\|WP_000742837.1\|2783645_2784485_-\|nucleoid-occlusion-protein	unknown	unknown	gnl\|CDD\|275105
NC_022442.1\|WP_000249657.1\|2785246_2787124_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NC_022442.1\|WP_000410770.1\|2775214_2775727_-\|HdeD-family-acid-resistance-protein	unknown	unknown	gnl\|CDD\|225786
NC_022442.1\|WP_000362507.1\|2787190_2788570_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NC_022442.1\|WP_000672036.1\|2780489_2780681_+\|peptide-resistance-ABC-transporter-activity-modulator-VraH	unknown	unknown	unknown
NC_022442.1\|WP_000215588.1\|2784527_2785247_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|234637
NC_022442.1\|WP_000672028.1\|2778737_2778929_+\|peptide-resistance-ABC-transporter-activity-modulator-VraH	unknown	unknown	unknown
NC_022442.1\|WP_000143679.1\|2776764_2778645_+\|peptide-resistance-ABC-transporter-permease-subunit-VraE	unknown	unknown	gnl\|CDD\|376899
NC_022442.1\|WP_000154165.1\|2776016_2776775_+\|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD	unknown	unknown	gnl\|CDD\|224059
NC_022442.1\|WP_001059079.1\|2781072_2781273_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_022442.1\|WP_000779135.1\|2782219_2782615_-\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|288237
NC_022442.1\|WP_000586238.1\|2779535_2780033_-\|hypothetical-protein	unknown	unknown	unknown
NC_022442.1\|WP_000491384.1\|2782682_2783036_-\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|288237
NC_022442.1\|WP_000240855.1\|2789187_2789325_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
NC_022442.1\|WP_001054123.1\|2781399_2781969_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_022442.1\|WP_001789343.1\|2788713_2789067_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782

Protein	Function_ID	Function_description	E-value
NC_022442.1\|WP_000742837.1\|2783645_2784485_-\|nucleoid-occlusion-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.327e-113
NC_022442.1\|WP_000249657.1\|2785246_2787124_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NC_022442.1\|WP_000215588.1\|2784527_2785247_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	3.12556e-96
NC_022442.1\|WP_000410770.1\|2775214_2775727_-\|HdeD-family-acid-resistance-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	3.26175e-22
NC_022442.1\|WP_000362507.1\|2787190_2788570_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NC_022442.1\|WP_000143679.1\|2776764_2778645_+\|peptide-resistance-ABC-transporter-permease-subunit-VraE	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.10596e-06
NC_022442.1\|WP_000154165.1\|2776016_2776775_+\|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.25186e-109
NC_022442.1\|WP_001059079.1\|2781072_2781273_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.4289e-30
NC_022442.1\|WP_000779135.1\|2782219_2782615_-\|DUF3147-family-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	6.39285e-39
NC_022442.1\|WP_000491384.1\|2782682_2783036_-\|DUF3147-family-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	1.88155e-38
NC_022442.1\|WP_000240855.1\|2789187_2789325_-\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	8.39798e-10
NC_022442.1\|WP_001054123.1\|2781399_2781969_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.69728e-16
NC_022442.1\|WP_001789343.1\|2788713_2789067_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	3.11548e-51

>NC_022442.1|WP_000491384.1|2782682_2783036_-|DUF3147-family-protein
MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFLAAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLTSLYINHKGYRKGAIFTVVCWFVISLAIFSIRHL
>NC_022442.1|WP_000779135.1|2782219_2782615_-|DUF3147-family-protein
MKLTLMKFFVGGFAVLLSYIVSVTLPWKEFGGIFATFPAVFLVSMFITGMQYGDKVAVHVSRGAVFGMTGVLVCILVTWMMLHMTHMWLISIIVGLLSWFISAVCIFEAVEFIAQKRLEKHSWKAGKTNSK
>NC_022442.1|WP_001054123.1|2781399_2781969_-|helix-turn-helix-transcriptional-regulator
MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDIHNLLMMCELFNVTLDDLVKGTIPFVPDIKVQRSLNLWAYVMIIFMTLAAILTGPLIVYWNWAWGITVMVIYGIGYYASMKIEDFKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNIKTSVLSFIAFVGAIILVALISMYLANKFL
>NC_022442.1|WP_001059079.1|2781072_2781273_+|cold-shock-protein
MNNGTVKWFNAEKGFGFIEQENGGDVFVHFSGIASDGYKTLEEGQKVTFEITEGQRGDQAVNVQTV
>NC_022442.1|WP_000672036.1|2780489_2780681_+|peptide-resistance-ABC-transporter-activity-modulator-VraH
MKFRELVKQSYEDLKNLTVTWYNVIALAMIVIVLSVVTTPIIGIPVGLLGGAYYLKRREEKGK
>NC_022442.1|WP_000586238.1|2779535_2780033_-|hypothetical-protein
MIINLETQQIHFDLEHETPYFQSPEKNRIRLDIDVLNKKQISNIINVIFNNQSKTKCTFLSEYLYPVKFREKTRIGRFFNITNWYEEIHSTDEKYVIATIKNIKNKDLIDYSLYIKKGLVEPFIVFYNQENIFYISNTVIDIISVSKDTLGYIKSEFNDHCASPY
>NC_022442.1|WP_000672028.1|2778737_2778929_+|peptide-resistance-ABC-transporter-activity-modulator-VraH
MKFRELVKQSYEDLKNLTVTWYNVIALAMIVIVLSSVTTPIIGIPAGLLGGAYYLKRREEKGK
>NC_022442.1|WP_000143679.1|2776764_2778645_+|peptide-resistance-ABC-transporter-permease-subunit-VraE
MTFNHIVLKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGVNNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRRTREFALFQLIGLTRQNILKMLALEQMIVFLITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTILMLIIAYILILFQSSLFLKRRSILSMMKDSIKTDVTTAKVTTAEVISGVLGIAMIALGYYMATEMFGTFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVVFTSSIMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLISMAPNEFNVVASQDAQQFESKLSQQHITFTKNYYETITVNNVKDQVITLENGSDSGRTNSILSANTKLTGNNAIITNTKSLPNIINIHLNKDLVVKGTKNETFRVTQEDKGKVYPLNLSFNSPVVEVSPEKYQQLKTQNNVHTFYGYDIKQTSQKEKAQAIAKQFGDKVITYDDMKKEVDATNGILIFVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNFGLPLLIAILHAVFAAIAFMKLMGNISFMPVIIVIIVYTLIYIVFALIAFVHSNKLIKKTI
>NC_022442.1|WP_000154165.1|2776016_2776775_+|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD
MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSGKTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAKFRKESLGFIFQDYSILPTLTVKENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYTSELSGGQQQRTAAARAFVHKPQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDGQIHTQLYQEGRSKQAFYEDIVHLQSVLGGVSNDI
>NC_022442.1|WP_000410770.1|2775214_2775727_-|HdeD-family-acid-resistance-protein
MEKGNQGIKWSSLIMGVLLLMLAVVIFTFPIENFYAITWLIGLFVLINGVIQIVYRRKAKALVGGNQNWILFMGIVDILFGLIVIFNVGASSAFFIYMFAFWFIFSSIAGLFTFSGSGSLKLISVIFNLLGIVFGVILLFNPLMGIVFISTMIAIAFVFVGVIYVVDALA
>NC_022442.1|WP_000742837.1|2783645_2784485_-|nucleoid-occlusion-protein
MKKPFSKLFGLKNKDDIIGHIEEDRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLRFAQDVTQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRIYKR
>NC_022442.1|WP_000215588.1|2784527_2785247_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNHLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
>NC_022442.1|WP_000249657.1|2785246_2787124_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
>NC_022442.1|WP_000362507.1|2787190_2788570_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINHLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
>NC_022442.1|WP_001789343.1|2788713_2789067_-|ribonuclease-P-protein-component
MLLEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
>NC_022442.1|WP_000240855.1|2789187_2789325_-|50S-ribosomal-protein-L34
MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	616645-616670	0	1.0
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	1149522-1149547	0	1.0
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	1149692-1149717	0	1.0
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	1286749-1286774	0	1.0
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	815997-816015	1	0.947
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	825166-825184	1	0.947
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	1286816-1286834	1	0.947
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	1286874-1286892	1	0.947
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	1980244-1980262	1	0.947
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	2320449-2320467	1	0.947
NC_022442_8	8.1\|2286175\|25\|NC_022442\|CRISPRCasFinder	2286175-2286199	25	NC_022442.1	1149578-1149602	1	0.96
NC_022442_8	8.1\|2286175\|25\|NC_022442\|CRISPRCasFinder	2286175-2286199	25	NC_022442.1	1874495-1874519	1	0.96
NC_022442_8	8.1\|2286175\|25\|NC_022442\|CRISPRCasFinder	2286175-2286199	25	NC_022442.1	2286231-2286255	1	0.96
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	779043-779068	1	0.962
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	779099-779124	1	0.962
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	825042-825067	1	0.962
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	1845649-1845674	1	0.962
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	2028516-2028541	1	0.962
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	2203769-2203794	1	0.962
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	2320507-2320532	1	0.962
NC_022442_1	1.1\|769611\|30\|NC_022442\|CRISPRCasFinder	769611-769640	30	NC_022442.1	810652-810681	2	0.933
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	183803-183821	2	0.895
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	616586-616604	2	0.895
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	926506-926524	2	0.895
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	1145441-1145459	2	0.895
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	1361452-1361470	2	0.895
NC_022442_2	2.2\|946797\|19\|NC_022442\|PILER-CR	946797-946815	19	NC_022442.1	1700238-1700256	2	0.895
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	2124431-2124456	2	0.923
NC_022442_10	10.1\|2783290\|26\|NC_022442\|CRISPRCasFinder	2783290-2783315	26	NC_022442.1	2124769-2124794	2	0.923

1. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 616645-616670, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

2. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 1149522-1149547, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

3. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 1149692-1149717, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

4. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 1286749-1286774, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

5. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 815997-816015, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacacc	Protospacer
**************** **

6. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 825166-825184, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacccc	Protospacer
****************.**

7. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 1286816-1286834, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacacc	Protospacer
**************** **

8. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 1286874-1286892, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacacc	Protospacer
**************** **

9. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 1980244-1980262, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacacc	Protospacer
**************** **

10. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 2320449-2320467, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacacc	Protospacer
**************** **

11. spacer 8.1|2286175|25|NC_022442|CRISPRCasFinder matches to position: 1149578-1149602, mismatch: 1, identity: 0.96

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgccagcttctgtgttggggccccg	Protospacer
**.**********************

12. spacer 8.1|2286175|25|NC_022442|CRISPRCasFinder matches to position: 1874495-1874519, mismatch: 1, identity: 0.96

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgtcagcttctatgttggggccccg	Protospacer
***********.*************

13. spacer 8.1|2286175|25|NC_022442|CRISPRCasFinder matches to position: 2286231-2286255, mismatch: 1, identity: 0.96

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgtcagcttctatgttggggccccg	Protospacer
***********.*************

14. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 779043-779068, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

15. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 779099-779124, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

16. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 825042-825067, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

17. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 1845649-1845674, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagctactatgttggggccccg	Protospacer
********* ****************

18. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 2028516-2028541, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgacagcttctatgttggggccccg	Protospacer
*** **********************

19. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 2203769-2203794, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

20. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 2320507-2320532, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

21. spacer 1.1|769611|30|NC_022442|CRISPRCasFinder matches to position: 810652-810681, mismatch: 2, identity: 0.933

cagagaaattggaacgccaatttctacagg	CRISPR spacer
caaagaaattggaacaccaatttctacagg	Protospacer
**.************.**************

22. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 183803-183821, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccccacc	Protospacer
************** * **

23. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 616586-616604, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctatgttggggcccacacc	Protospacer
**.************* **

24. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 926506-926524, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccgcccc	Protospacer
**************.*.**

25. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 1145441-1145459, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctatgttggggcccacccc	Protospacer
**.*************.**

26. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 1361452-1361470, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggagcccacccc	Protospacer
*********.******.**

27. spacer 2.2|946797|19|NC_022442|PILER-CR matches to position: 1700238-1700256, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggccccatcc	Protospacer
**************  ***

28. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 2124431-2124456, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtcttggggccccg	Protospacer
************.* ***********

29. spacer 10.1|2783290|26|NC_022442|CRISPRCasFinder matches to position: 2124769-2124794, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttttgtgttggggccccg	Protospacer
**********.*.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_022442_1	1.1\|769611\|30\|NC_022442\|CRISPRCasFinder	769611-769640	30	KC139649	Salmonella phage FSL SP-069 hypothetical proteins, RdgC exonuclease, hypothetical proteins, TerL, hypothetical proteins, deoxyuridine 5'-triphosphate nucleotidohydrolase, hypothetical proteins, NinH, head morphogenesis protein, hypothetical proteins, capsid related protein, hypothetical proteins, enolase-like protein, hypothetical proteins, tail fiber, hypothetical protein, putative endolysin, hypothetical proteins, and DNA polymerase genes, complete cds	9669-9698	9	0.7
NC_022442_1	1.1\|769611\|30\|NC_022442\|CRISPRCasFinder	769611-769640	30	KC139636	Salmonella phage FSL SP-062 hypothetical proteins, RdgC exonuclease, hypothetical proteins, TerL, and hypothetical proteins genes, complete cds	9669-9698	9	0.7
NC_022442_1	1.1\|769611\|30\|NC_022442\|CRISPRCasFinder	769611-769640	30	NC_025443	Salmonella phage 9NA, complete genome	7835-7864	9	0.7
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NZ_CP024776	Bacillus thuringiensis LM1212 plasmid pLM8, complete sequence	3826-3857	9	0.719
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NZ_CP009062	Borreliella afzelii K78 plasmid lp28-1, complete sequence	16532-16563	10	0.688
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NZ_CP018749	Borreliella garinii strain CIP 103362 isolate 20047 plasmid lp28-7	15178-15209	10	0.688
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NZ_CP028869	Borreliella garinii strain 20047 plasmid lp28-7, complete sequence	11910-11941	10	0.688
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NZ_CP028878	Borreliella bavariensis PBi plasmid lp28-7, complete sequence	4741-4772	10	0.688
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NZ_CP028879	Borreliella bavariensis PBi plasmid lp28-9, complete sequence	11876-11907	10	0.688
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NZ_CP017215	Borreliella burgdorferi strain B331 plasmid B331_lp28_6, complete sequence	11994-12025	10	0.688
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NC_018987	Borrelia burgdorferi 297 plasmid 297_lp28-6, complete sequence	12713-12744	15	0.531
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NC_017412	Borreliella burgdorferi JD1 plasmid JD1 lp28-7, complete sequence	17252-17283	15	0.531
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NC_017419	Borreliella burgdorferi N40 plasmid N40_lp28-2, complete sequence	17030-17061	15	0.531
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NC_017408	Borreliella burgdorferi JD1 plasmid JD1 lp28-6, complete sequence	14812-14843	15	0.531
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NC_015920	Borreliella bissettii DN127 plasmid lp56, complete sequence	16601-16632	15	0.531
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NC_011779	Borreliella burgdorferi ZS7 plasmid ZS7_lp28-2, complete sequence	16934-16965	15	0.531
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NC_001852	Borreliella burgdorferi B31 plasmid lp28-2, complete sequence	16891-16922	15	0.531
NC_022442_6	6.1\|1978816\|32\|NC_022442\|CRISPRCasFinder	1978816-1978847	32	NZ_CP017219	Borreliella burgdorferi strain B331 plasmid B331_lp56, complete sequence	14876-14907	15	0.531

1. spacer 1.1|769611|30|NC_022442|CRISPRCasFinder matches to KC139649 (Salmonella phage FSL SP-069 hypothetical proteins, RdgC exonuclease, hypothetical proteins, TerL, hypothetical proteins, deoxyuridine 5'-triphosphate nucleotidohydrolase, hypothetical proteins, NinH, head morphogenesis protein, hypothetical proteins, capsid related protein, hypothetical proteins, enolase-like protein, hypothetical proteins, tail fiber, hypothetical protein, putative endolysin, hypothetical proteins, and DNA polymerase genes, complete cds) position: , mismatch: 9, identity: 0.7

cagagaaattggaacgccaatttctacagg	CRISPR spacer
agctttaattggtacgccaatttctacatc	Protospacer
 .    ****** ***************

2. spacer 1.1|769611|30|NC_022442|CRISPRCasFinder matches to KC139636 (Salmonella phage FSL SP-062 hypothetical proteins, RdgC exonuclease, hypothetical proteins, TerL, and hypothetical proteins genes, complete cds) position: , mismatch: 9, identity: 0.7

cagagaaattggaacgccaatttctacagg	CRISPR spacer
agctttaattggtacgccaatttctacatc	Protospacer
 .    ****** ***************

3. spacer 1.1|769611|30|NC_022442|CRISPRCasFinder matches to NC_025443 (Salmonella phage 9NA, complete genome) position: , mismatch: 9, identity: 0.7

cagagaaattggaacgccaatttctacagg	CRISPR spacer
agctttaattggtacgccaatttctacatc	Protospacer
 .    ****** ***************

4. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NZ_CP024776 (Bacillus thuringiensis LM1212 plasmid pLM8, complete sequence) position: , mismatch: 9, identity: 0.719

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
caaattaggatttcttttttcgaaatccttga	Protospacer
     ***.*****************.**. *

5. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NZ_CP009062 (Borreliella afzelii K78 plasmid lp28-1, complete sequence) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggaaatagaatttgttttttagaaattcttgt	Protospacer
.   .******** ****** ********.

6. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NZ_CP018749 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid lp28-7) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggaaatagaatttgttttttagaaattcttgt	Protospacer
.   .******** ****** ********.

7. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NZ_CP028869 (Borreliella garinii strain 20047 plasmid lp28-7, complete sequence) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggaaatagaatttgttttttagaaattcttgt	Protospacer
.   .******** ****** ********.

8. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NZ_CP028878 (Borreliella bavariensis PBi plasmid lp28-7, complete sequence) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggaaatagaatttgttttttagaaattcttgt	Protospacer
.   .******** ****** ********.

9. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NZ_CP028879 (Borreliella bavariensis PBi plasmid lp28-9, complete sequence) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggaaatagaatttgttttttagaaattcttgt	Protospacer
.   .******** ****** ********.

10. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NZ_CP017215 (Borreliella burgdorferi strain B331 plasmid B331_lp28_6, complete sequence) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggcaacagaatttgttttttagaaattcttgt	Protospacer
. * ..******* ****** ********.

11. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NC_018987 (Borrelia burgdorferi 297 plasmid 297_lp28-6, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

12. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NC_017412 (Borreliella burgdorferi JD1 plasmid JD1 lp28-7, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

13. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NC_017419 (Borreliella burgdorferi N40 plasmid N40_lp28-2, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

14. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NC_017408 (Borreliella burgdorferi JD1 plasmid JD1 lp28-6, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

15. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NC_015920 (Borreliella bissettii DN127 plasmid lp56, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

16. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NC_011779 (Borreliella burgdorferi ZS7 plasmid ZS7_lp28-2, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

17. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NC_001852 (Borreliella burgdorferi B31 plasmid lp28-2, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

18. spacer 6.1|1978816|32|NC_022442|CRISPRCasFinder matches to NZ_CP017219 (Borreliella burgdorferi strain B331 plasmid B331_lp56, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

747933 : 755753

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|747933_748989_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|748988_749675_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|749649_750123_-	DoxX family protein	NA	NA	NA	NA
WP_001093553.1\|750464_750905_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637683.1\|751184_751769_-	hypothetical protein	NA	NA	NA	NA
WP_001062976.1\|751867_752581_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|752584_753004_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|753005_753674_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604508.1\|754024_754618_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	6.8e-39	44.0
WP_001217800.1\|754601_755753_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	6.0e-23	36.1

DBSCAN-SWA_2

767734 : 782243

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663039.1\|767734_768793_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.4e-21	26.4
WP_000197262.1\|768951_769494_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429011.1\|770101_771019_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	6.2e-07	22.0
WP_031760357.1\|771111_771213_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|771290_772796_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|773135_773636_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|773655_774522_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|775321_775720_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855509.1\|775682_777788_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.6
WP_000562498.1\|777905_778877_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|779376_779532_+	hypothetical protein	NA	NA	NA	NA
WP_000876317.1\|779570_780542_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	3.6e-138	78.6
WP_001245572.1\|780528_781485_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616873.1\|781481_782243_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_3

862738 : 884239

Staphylococcus_phage(77.78%)

terminase,coat,integrase

attL 861045:861066|attR 881707:881728

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
861045:861066	attL	NA	NA	NA	NA
WP_000571213.1\|862738_863764_+	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.4e-28	36.8
WP_000520233.1\|863756_864452_+	ABC transporter permease	NA	NA	NA	NA
WP_000732334.1\|864469_865291_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000266157.1\|865433_866654_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	6.4e-100	47.5
WP_000733774.1\|866741_867470_-	staphylococcal enterotoxin type K	A0EX09	Staphylococcus_phage	5.5e-22	31.8
WP_001033318.1\|867493_868222_-	staphylococcal enterotoxin type Q	A0EX09	Staphylococcus_phage	1.0e-28	35.4
WP_001228759.1\|868291_868723_-	hypothetical protein	Q4ZCB6	Staphylococcus_virus	5.1e-36	56.0
WP_000281657.1\|868739_869198_-	ImmA/IrrE family metallo-endopeptidase	A0A0H4J322	Staphylococcus_phage	5.1e-66	83.0
WP_001260004.1\|869209_869542_-	helix-turn-helix transcriptional regulator	A0A1J0MFC1	Staphylococcus_phage	1.6e-37	74.5
WP_000243851.1\|869734_869998_+	helix-turn-helix transcriptional regulator	A0A2H4J9X2	uncultured_Caudovirales_phage	3.1e-36	94.8
WP_000091731.1\|869990_870263_+	winged helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	9.7e-41	90.0
WP_000784875.1\|870274_870421_+	hypothetical protein	NA	NA	NA	NA
WP_001058486.1\|870413_870623_+	hypothetical protein	Q4ZE76	Staphylococcus_phage	1.7e-29	94.2
WP_001103942.1\|870625_870946_+	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	1.3e-20	51.9
WP_001002732.1\|871009_871879_+	primase alpha helix C-terminal domain-containing protein	A0A1W6JQL5	Staphylococcus_phage	3.4e-156	92.7
WP_000390454.1\|871895_873365_+	hypothetical protein	A0A1W6JQD6	Staphylococcus_phage	2.9e-288	99.0
WP_001039168.1\|873650_874013_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	8.9e-66	99.2
WP_000998181.1\|874014_874299_+	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	1.9e-47	95.7
WP_001019764.1\|874295_874937_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	1.5e-108	91.5
WP_001190615.1\|875453_875795_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	1.4e-57	99.1
WP_000846285.1\|875806_876385_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.4e-28	38.4
WP_000448773.1\|876402_876621_+	hypothetical protein	NA	NA	NA	NA
WP_000771368.1\|876671_877199_+\|coat	spore coat protein	A0A1W6JQH7	Staphylococcus_phage	3.5e-87	97.1
WP_045181470.1\|877330_877543_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	1.1e-31	98.6
WP_001293067.1\|877539_878109_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.0e-100	97.9
WP_000278085.1\|878416_879217_+	staphylococcal enterotoxin type B	A0A097PAT7	Streptococcus_pyogenes_phage	1.0e-53	49.4
WP_001035631.1\|879294_879852_-	DUF4888 domain-containing protein	A0A1W6JQE5	Staphylococcus_phage	1.4e-70	73.8
WP_001795626.1\|880225_880378_+	hypothetical protein	A0A0F6N3H2	Staphylococcus_phage	7.6e-19	98.0
WP_000139423.1\|880448_880559_+	hypothetical protein	W5R8J7	Staphylococcus_phage	1.7e-12	100.0
WP_001286805.1\|880560_880746_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.7e-26	100.0
WP_000752917.1\|881869_882064_+	CsbD family protein	NA	NA	NA	NA
881707:881728	attR	NA	NA	NA	NA
WP_001183851.1\|882297_883149_-	DUF368 domain-containing protein	NA	NA	NA	NA
WP_000168845.1\|883477_884239_+	Fe-S cluster assembly ATPase SufC	A0A1V0SE00	Indivirus	4.4e-06	23.3

DBSCAN-SWA_4

974186 : 1018240

Streptococcus_phage(40.0%)

tRNA,bacteriocin,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000448937.1\|974186_975176_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_000258003.1\|975470_975866_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_001217728.1\|976236_976956_+	adaptor protein MecA	NA	NA	NA	NA
WP_000959298.1\|977076_978063_+	competence protein CoiA	NA	NA	NA	NA
WP_000082725.1\|978110_979919_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5
WP_000896697.1\|980378_981185_-\|protease	protease adaptor protein YjbH	NA	NA	NA	NA
WP_000214067.1\|981207_981573_-	truncated hemoglobin	NA	NA	NA	NA
WP_000224622.1\|981676_982270_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_001242107.1\|982455_982803_+	hypothetical protein	NA	NA	NA	NA
WP_001077683.1\|982819_983455_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_001270834.1\|983471_984281_+	NAD kinase	NA	NA	NA	NA
WP_000669925.1\|984277_985132_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000062407.1\|985152_986538_+	magnesium transporter	NA	NA	NA	NA
WP_000395162.1\|986547_988392_+	monovalent cation:proton antiporter family protein	NA	NA	NA	NA
WP_000933195.1\|988670_989441_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_000933105.1\|989637_990723_-	AI-2E family transporter	NA	NA	NA	NA
WP_000570701.1\|991064_992633_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_000889183.1\|992775_993534_+	esterase family protein	NA	NA	NA	NA
WP_001060547.1\|993699_994425_+	hypothetical protein	NA	NA	NA	NA
WP_000355328.1\|994426_995278_+	hypothetical protein	NA	NA	NA	NA
WP_000600387.1\|996012_996522_+	2'-5' RNA ligase family protein	NA	NA	NA	NA
WP_001154228.1\|996634_997825_-	MFS transporter	NA	NA	NA	NA
WP_000258650.1\|997802_998978_-	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_000340127.1\|999410_1000895_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_001798480.1\|1000875_1001136_+	YueH family protein	NA	NA	NA	NA
WP_001049958.1\|1001135_1002698_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	3.2e-35	28.0
WP_000928413.1\|1002999_1003803_+	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_078064575.1\|1004018_1006343_+\|protease	serine protease	W5SAB9	Pithovirus	2.1e-11	27.4
WP_000021872.1\|1006359_1007718_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000414178.1\|1007856_1009368_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000287265.1\|1009856_1010426_-	competence protein ComK	NA	NA	NA	NA
WP_000876826.1\|1010635_1010854_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000668820.1\|1010934_1011921_-	lipoate--protein ligase	NA	NA	NA	NA
WP_000214898.1\|1012119_1012296_+	YkvS family protein	NA	NA	NA	NA
WP_001033867.1\|1012310_1012913_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_014363402.1\|1013308_1014955_+\|transposase	IS1182 family transposase	A0A146ICT8	Staphylococcus_phage	3.7e-292	99.3
WP_029656376.1\|1015965_1016232_+\|bacteriocin	bacteriocin transporter	NA	NA	NA	NA
WP_000870825.1\|1016275_1018240_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA

DBSCAN-SWA_5

1050446 : 1058919

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861570.1\|1050446_1050929_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.0e-22	44.7
WP_001010401.1\|1050915_1052040_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174047.1\|1052043_1052748_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	1.4e-46	41.2
WP_000848350.1\|1052747_1053011_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1053012_1053684_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032747.1\|1053676_1055866_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.8e-140	39.7
WP_000483727.1\|1055844_1057329_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.6e-44	31.5
WP_000030810.1\|1057321_1058350_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000238670.1\|1058352_1058919_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-29	40.1

DBSCAN-SWA_6

1316911 : 1321860

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001659797.1\|1316911_1317109_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	48.4
WP_078065144.1\|1317797_1318022_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	4.3e-18	71.0
WP_001002343.1\|1318317_1318524_+	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.9e-12	56.7
WP_001788716.1\|1319219_1319330_+	hypothetical protein	NA	NA	NA	NA
WP_000006110.1\|1319758_1319944_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
WP_000477491.1\|1320455_1320560_+	hypothetical protein	NA	NA	NA	NA
WP_000956747.1\|1320686_1320938_+	hypothetical protein	NA	NA	NA	NA
WP_001813273.1\|1321411_1321666_+	hypothetical protein	A0A1J0MF61	Staphylococcus_phage	1.4e-25	62.7
WP_000780597.1\|1321665_1321860_+	hypothetical protein	A0A1J0MG79	Staphylococcus_phage	2.8e-18	71.4

DBSCAN-SWA_7

1498712 : 1575708

107

Staphylococcus_phage(84.15%)

tRNA,tail,protease,portal,terminase,integrase,capsid,holin,head

attL 1558530:1558544|attR 1576512:1576526

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000858801.1\|1498712_1500005_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.5e-54	30.0
WP_000525064.1\|1500326_1503020_-	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	1.1e-46	34.6
WP_000049916.1\|1503043_1504015_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_000361537.1\|1504001_1505204_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	5.4e-35	43.3
WP_000690024.1\|1505208_1506351_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000839926.1\|1506608_1506926_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_001827022.1\|1507261_1507942_-	zinc metallopeptidase	NA	NA	NA	NA
WP_000154692.1\|1508013_1508601_-	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_000005216.1\|1508590_1509166_-	YpiB family protein	G3MAV7	Bacillus_virus	2.7e-08	27.2
WP_000389518.1\|1509179_1510424_-	hypothetical protein	NA	NA	NA	NA
WP_000245912.1\|1510430_1511729_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000776330.1\|1511738_1512803_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_001269940.1\|1512828_1513995_-	chorismate synthase	A0A291AU41	Pandoravirus	2.6e-34	32.3
WP_000789522.1\|1514381_1514582_-	hypothetical protein	NA	NA	NA	NA
WP_000442477.1\|1514791_1515241_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_001096478.1\|1515332_1516292_-	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000774684.1\|1516293_1517019_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_000450555.1\|1517021_1517594_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_001043863.1\|1518024_1518297_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000161742.1\|1518467_1519466_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000165530.1\|1519482_1520793_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_000133960.1\|1521009_1522185_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_031844924.1\|1522440_1522632_-	hypothetical protein	NA	NA	NA	NA
WP_031844926.1\|1522748_1522853_-	hypothetical protein	NA	NA	NA	NA
WP_000644394.1\|1522895_1523555_-	(d)CMP kinase	NA	NA	NA	NA
WP_000681761.1\|1523631_1524600_+	asparaginase	NA	NA	NA	NA
WP_001174260.1\|1524714_1525701_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_001824277.1\|1525861_1525978_-	hypothetical protein	NA	NA	NA	NA
WP_000069308.1\|1526102_1527563_-	elastin-binding protein EbpS	NA	NA	NA	NA
WP_000902114.1\|1527715_1529095_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.2e-56	33.6
WP_001163813.1\|1529084_1530038_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001151997.1\|1530145_1530394_+	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001186908.1\|1530499_1531045_-	ECF transporter S component	NA	NA	NA	NA
WP_000476869.1\|1531447_1532392_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000476889.1\|1532449_1533355_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000470325.1\|1533445_1533631_-	hypothetical protein	A0ZS61	Staphylococcus_virus	1.9e-24	96.7
WP_024937002.1\|1533879_1534863_-	Panton-Valentine bi-component leukocidin subunit F	A0A2I6PEU3	Staphylococcus_phage	4.0e-185	100.0
WP_000239544.1\|1534858_1535797_-	beta-channel forming cytolysin	A0A2I6PF61	Staphylococcus_phage	1.7e-180	100.0
WP_000909204.1\|1536186_1537641_-	N-acetylmuramoyl-L-alanine amidase	A0A2I6PF47	Staphylococcus_phage	7.5e-289	100.0
WP_000339141.1\|1537651_1537954_-\|holin	phage holin	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
WP_000340977.1\|1538079_1538454_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_001040259.1\|1538509_1538797_-	hypothetical protein	G4KNR2	Staphylococcus_phage	9.9e-44	100.0
WP_001153681.1\|1538843_1538996_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
WP_000582126.1\|1538985_1542771_-	hypothetical protein	G4KNR1	Staphylococcus_phage	0.0e+00	100.0
WP_000567420.1\|1542786_1544271_-\|tail	phage tail family protein	G4KNR0	Staphylococcus_phage	1.6e-299	100.0
WP_000504558.1\|1544270_1548812_-\|tail	phage tail tape measure protein	A0A2I6PE03	Staphylococcus_phage	0.0e+00	100.0
WP_001096355.1\|1549056_1549407_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_071621395.1\|1549456_1549681_-	Ig-like domain-containing protein	A0A075LYE8	Staphylococcus_phage	3.0e-32	100.0
WP_000268740.1\|1549722_1550367_-\|tail	phage tail protein	G4KNQ7	Staphylococcus_phage	6.5e-120	100.0
WP_000565498.1\|1550367_1550775_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000114226.1\|1550771_1551176_-	HK97 gp10 family phage protein	G4KNQ5	Staphylococcus_phage	4.3e-69	100.0
WP_000755150.1\|1551172_1551535_-\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
WP_000150936.1\|1551518_1551803_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000238236.1\|1551792_1552077_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
WP_000154559.1\|1552096_1553242_-\|capsid	phage major capsid protein	G4KNQ3	Staphylococcus_phage	9.6e-215	100.0
WP_000642728.1\|1553265_1554003_-\|protease	Clp protease ClpP	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
WP_000025272.1\|1553986_1555174_-\|portal	phage portal protein	G4KNQ1	Staphylococcus_phage	4.6e-220	100.0
WP_000625097.1\|1555189_1556851_-\|terminase	terminase large subunit	G4KNQ0	Staphylococcus_phage	0.0e+00	100.0
WP_000402904.1\|1556847_1557192_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000988330.1\|1557322_1557622_-	HNH endonuclease	G4KNP8	Staphylococcus_phage	4.6e-52	100.0
WP_000590122.1\|1557853_1558270_-	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
WP_000265043.1\|1558297_1558498_-	DUF1514 family protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
WP_001005262.1\|1558497_1559148_-	hypothetical protein	D2JLD8	Staphylococcus_phage	8.9e-117	100.0
1558530:1558544	attL	NA	NA	NA	NA
WP_000237868.1\|1559306_1559456_-	transcriptional activator RinB	A0A2I6PDY4	Staphylococcus_phage	1.1e-17	98.0
WP_001125015.1\|1559458_1559659_-	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_000195782.1\|1559633_1559822_-	DUF1381 domain-containing protein	A0A2I6PDV0	Staphylococcus_phage	2.1e-26	100.0
WP_001282074.1\|1559818_1560064_-	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
WP_001061834.1\|1560100_1560607_-	dUTP diphosphatase	G4KNP5	Staphylococcus_phage	1.0e-91	100.0
WP_000889683.1\|1560621_1560783_-	hypothetical protein	A0A2I6PDW5	Staphylococcus_phage	2.4e-23	100.0
WP_000454994.1\|1560783_1561065_-	hypothetical protein	A0A2I6PDX3	Staphylococcus_phage	8.5e-48	100.0
WP_000028424.1\|1561065_1561239_-	hypothetical protein	A0A2H4PQJ2	Staphylococcus_phage	1.8e-24	100.0
WP_001065099.1\|1561228_1561480_-	DUF1024 family protein	G4KNP4	Staphylococcus_phage	6.4e-39	100.0
WP_000131388.1\|1561494_1561737_-	hypothetical protein	A0A2I6PDU1	Staphylococcus_phage	3.9e-41	100.0
WP_000029366.1\|1561740_1562097_-	hypothetical protein	G4KNP3	Staphylococcus_phage	1.1e-60	100.0
WP_001187236.1\|1562097_1562283_-	DUF3113 family protein	A0A068A236	Staphylococcus_phage	7.8e-26	95.1
WP_021758092.1\|1562287_1562692_-	DUF1064 domain-containing protein	A0A059T5A5	Staphylococcus_phage	8.4e-73	98.5
WP_001123669.1\|1562701_1562923_-	DUF3269 family protein	A0A2I6PDV8	Staphylococcus_phage	1.7e-35	100.0
WP_000256594.1\|1562935_1563094_-	hypothetical protein	A0A2I6PDX0	Staphylococcus_phage	4.5e-22	98.1
WP_021758094.1\|1563087_1563867_-	ATP-binding protein	G4KNP1	Staphylococcus_phage	2.4e-145	99.2
WP_021758096.1\|1563876_1564647_-	phage protein	G4KNP0	Staphylococcus_phage	1.9e-121	99.6
WP_000414755.1\|1564712_1564994_+	hypothetical protein	A0A1W6JPU7	Staphylococcus_phage	2.6e-49	100.0
WP_001081076.1\|1564986_1565136_-	hypothetical protein	A7TWN0	Staphylococcus_phage	2.4e-17	100.0
WP_000057262.1\|1565132_1565807_-	hypothetical protein	G4KNN9	Staphylococcus_phage	8.6e-131	100.0
WP_001099007.1\|1565818_1566262_-	single-stranded DNA-binding protein	G4KNN8	Staphylococcus_phage	1.4e-76	100.0
WP_000840496.1\|1566258_1566909_-	ERF family protein	A0A0F6N3I5	Staphylococcus_phage	1.1e-119	100.0
WP_001004336.1\|1566909_1567446_-	host-nuclease inhibitor Gam family protein	A0A0F6N4M6	Staphylococcus_phage	1.4e-80	100.0
WP_001556704.1\|1567458_1567719_-	DUF1108 family protein	G4KNN5	Staphylococcus_phage	2.0e-43	100.0
WP_000829613.1\|1567723_1568041_-	hypothetical protein	Q4ZAS8	Staphylococcus_virus	3.9e-33	100.0
WP_001285954.1\|1568129_1568291_-	DUF1270 domain-containing protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
WP_001124198.1\|1568302_1568566_-	helix-turn-helix domain-containing protein	A0A2I6PEL8	Staphylococcus_phage	2.5e-46	100.0
WP_001037095.1\|1568595_1568814_-	hypothetical protein	A0A2I6PDV4	Staphylococcus_phage	5.0e-32	100.0
WP_001662405.1\|1569212_1569350_-	hypothetical protein	A0ZS11	Staphylococcus_virus	3.7e-17	97.8
WP_000435343.1\|1569369_1569630_-	hypothetical protein	A0A2I6PDT7	Staphylococcus_phage	3.5e-40	100.0
WP_001148617.1\|1569642_1570395_-	phage antirepressor KilAC domain-containing protein	G4KNN1	Staphylococcus_phage	1.1e-139	100.0
WP_000801108.1\|1570455_1570683_+	hypothetical protein	A7TWL9	Staphylococcus_phage	1.7e-38	100.0
WP_000502678.1\|1570684_1570876_-	hypothetical protein	A0A2I6PDT1	Staphylococcus_phage	9.5e-27	100.0
WP_000772137.1\|1570932_1571142_+	hypothetical protein	A0A2I6PDR8	Staphylococcus_phage	9.1e-31	100.0
WP_000939495.1\|1571134_1571275_-	hypothetical protein	A0A2I6PDT8	Staphylococcus_phage	1.9e-16	100.0
WP_000435346.1\|1571289_1571733_-	hypothetical protein	G4KNN0	Staphylococcus_phage	2.0e-75	100.0
WP_021758098.1\|1571745_1571985_-	helix-turn-helix transcriptional regulator	G4KNM9	Staphylococcus_phage	2.0e-37	98.7
WP_000094093.1\|1572155_1572863_+	helix-turn-helix transcriptional regulator	G4KNM8	Staphylococcus_phage	7.7e-130	100.0
WP_001049399.1\|1572874_1573030_+	hypothetical protein	A0A2I6PDR9	Staphylococcus_phage	6.3e-21	100.0
WP_001089804.1\|1573016_1573202_+	hypothetical protein	A0A2I6PDS4	Staphylococcus_phage	2.3e-25	100.0
WP_000705240.1\|1573401_1573584_+	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
WP_001013104.1\|1573619_1573766_+	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.1e-14	89.6
WP_000191466.1\|1573762_1574377_-	hypothetical protein	A0A2I6PEZ0	Staphylococcus_phage	6.7e-106	100.0
WP_000264751.1\|1574502_1575708_+\|integrase	site-specific integrase	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
1576512:1576526	attR	NA	NA	NA	NA

DBSCAN-SWA_8

1636523 : 1644835

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1636523_1637309_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924210.1\|1637434_1638325_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	33.1
WP_001062177.1\|1638334_1639681_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683914.1\|1639794_1640895_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	1.0e-08	30.6
WP_000624567.1\|1640897_1641575_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1641705_1642812_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217251.1\|1643035_1644835_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0

DBSCAN-SWA_9

1715480 : 1724523

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364543.1\|1715480_1715999_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.1e-28	45.8
WP_000594983.1\|1716020_1718294_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	2.1e-64	29.5
WP_000749798.1\|1718496_1720776_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1721050_1721311_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1721329_1722469_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019166.1\|1722491_1723517_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|1723518_1724523_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_10

1850364 : 1896291

Staphylococcus_phage(94.29%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001050576.1\|1850364_1856922_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.2e-290	93.2
WP_000836467.1\|1857247_1857559_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	5.3e-51	98.1
WP_001557386.1\|1857580_1859998_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
WP_001025062.1\|1860286_1861468_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	1.2e-217	99.5
WP_000526539.1\|1861577_1862531_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764429.1\|1862527_1863091_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	9.2e-102	98.9
WP_000757543.1\|1863210_1863612_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266100.1\|1864183_1865011_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014937042.1\|1865013_1865133_-	hypothetical protein	NA	NA	NA	NA
WP_001196343.1\|1865244_1866246_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	1.7e-183	98.8
WP_001008551.1\|1866367_1866832_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159028.1\|1866844_1868026_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.6e-225	99.2
WP_000493883.1\|1868036_1868669_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.4e-111	98.6
WP_000077340.1\|1868675_1869719_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.2e-195	98.5
WP_001261664.1\|1870199_1871702_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.1e-29	98.6
WP_000221186.1\|1872223_1872538_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	1.4e-51	95.2
WP_000989100.1\|1872537_1873830_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	2.2e-223	97.4
WP_000163239.1\|1873847_1874240_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	6.9e-72	99.2
WP_001032836.1\|1874644_1875499_-	N-acetylglucosaminidase	Q4ZCC7	Staphylococcus_virus	4.9e-38	38.1
WP_000384172.1\|1875774_1875999_-	hypothetical protein	NA	NA	NA	NA
WP_001153740.1\|1876776_1877220_+	competence protein ComK	NA	NA	NA	NA
WP_001030460.1\|1877206_1877650_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	5.4e-57	98.0
WP_025175276.1\|1877947_1878583_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_000492902.1\|1878749_1879370_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001096492.1\|1879838_1880552_-	transaldolase	M1PR54	Cyanophage	1.2e-18	34.5
WP_000091445.1\|1880809_1881112_+	hypothetical protein	NA	NA	NA	NA
WP_001200550.1\|1881367_1881733_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	6.2e-59	98.3
WP_000623471.1\|1881729_1882083_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_000453310.1\|1882332_1883166_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.3e-157	99.3
WP_000366163.1\|1883377_1884286_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000933822.1\|1884410_1885604_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109912.1\|1885975_1887568_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_078065176.1\|1887861_1888608_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	7.8e-141	98.0
WP_000672009.1\|1888612_1889086_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	3.6e-83	98.1
WP_000718107.1\|1889151_1889409_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778518.1\|1889405_1890407_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.9
WP_000348384.1\|1890411_1891890_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.4e-281	96.7
WP_078065177.1\|1892049_1892505_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	4.0e-79	97.9
WP_078065147.1\|1892807_1893458_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	1.2e-31	68.1
WP_000070638.1\|1893538_1894534_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	1.7e-66	92.7
WP_000669039.1\|1894609_1895236_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	5.8e-81	84.6
WP_000627534.1\|1895276_1895618_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	2.8e-53	93.8
WP_000414219.1\|1895718_1896291_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8

DBSCAN-SWA_11

1901845 : 1910160

Staphylococcus_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001044434.1\|1901845_1902700_-	M23 family metallopeptidase	E5G070	Clostridium_phage	6.4e-06	37.9
WP_051335094.1\|1902950_1903496_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	1.8e-09	32.5
WP_000669789.1\|1903912_1904092_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_001791826.1\|1904402_1904663_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702263.1\|1904715_1905066_-	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_000727649.1\|1905750_1906200_+	chemotaxis-inhibiting protein CHIPS	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
WP_001066124.1\|1906931_1907693_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.1e-54	44.2
WP_000777467.1\|1907685_1908978_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	2.6e-14	30.8
WP_000206347.1\|1909371_1910160_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	7.0e-140	95.4

Anti-CRISPR protein detection

Acr_ID: NC_022442.1|WP_000384172.1|1875774_1875999_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_022442.1|WP_000384172.1|1875774_1875999_-|hypothetical-protein

1875774_1875999_-

74 aa aa

1850364-1896291

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_022442_8	Orphan	8.1\|2286175\|25\|NC_022442\|CRISPRCasFinder	2286175-2286199	25	1874495-1874519	1

1. spacer 8.1|2286175|25|NC_022442|CRISPRCasFinder matches to NC_022442 position: 1874495-1874519, mismatch: 1

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgtcagcttctatgttggggccccg	Protospacer
***********.*************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022442

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information