CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022525	Salmonella enterica subsp. enterica serovar Thompson str. RM6836, complete sequence	3 crisprs	WYL,DinG,cas3,DEDDh,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	0	24	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_022525_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022525_1

2931638-2933316

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

27 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NC_022525_1

>merge|NC_022525|1|2931638-2933316|CRISPRCasFinder,CRT,PILER-CR
GTGTTTATCCCCGTTGGCGCGGGGAACATTTTTCAGCCCTTGCCGACTGCGGAACGCCCCTCGGTTTATCCCCGCTGGCGCGGGGAACACATGGATGGCTCATATCCGGTTTCTGTTTCTGCCGGTTTATCCCCGCTGGCGCGGGGAACACTTCGGTAACGTCTGGATTATTTTCTGAGGGTTCGGTTTATCCCCGCTGGCGCGGGGAACACGTGCTGCTGCTGATCAGTTTACCCGCTGGGTGCGGTTTATCCCCGCTGGCGCGGGGAACACGTTTATTACTGCTTAGTTAATTAATGGGTTGCCGGTTTATCCCCGCTGGCGCGGGGAACACAGGCGAATAATCTCTAATAGTCTCAATTCGTTCGGTTTATCCCCGCTGGCGCGGGGAACACGCCGATCGATGGCAAAGTTACCGATCCCTATCCCGGTTTATCCCCGCTGGCGCGGGGAACACTGATATTCCGGAACCTGACCCGCAACTACAGTCGGTTTATCCCCGCTGGCGCGGGGAACACACGTCGCTGTTAATCTCCTCGTTAAGAAGCTGCGGTTTATCCCCGCTGGCGCGGGGAACACCCCGACAGTTGCTCAGGTGGCTGCCGCCAAGGCGGTTTATCCCCGCTGGCGCGGGGAACACGACGACAAAATTAATATTGTTGGCTGGCGTGTCGGTTTATCCCCGCTGACGCGGGGAACACCGTAAATTTTGCTGTAATCAACTGTGCTGTCCCGGTTTATCCCCGCTGGCGCGGGGAACACTTCAGAGAATTGCCGCCAATAGAACAGCGCAACGGTTTATCCCCGCTGGCGCGGGGAACACGTCTCCGCAAAGGAAGCAGAGCTGTTCTGCGACGGTTTATCCCCGCTGGCGCGGGGAACACGCTGTCGTATATCCGTTACGCAACCCGCGTGCGCGGTTTATCCCCGCTGGCGCGGGGAACACGCTTGCCAGTGGATTTTTGGTTATCTATGTAGTCGGTTTATCCCCGCTGGCGCGGGGAACACGCGAATGCAGCCCCTCTAAAATTGTTGCCCGCCGGTTTATCCCCGCTGGCGCGGGGAACACACTGGAGGAGAATTTGATGCAGGTGAAGCGTCCGGTTTATCCCCGCTGGCGCGGGGAACACCAGTGGTGTTTAAGCCCGACGTCGGCAACAGCCGGTTTATCCCCGCTGGCGCGGGGAACACGTGAGTTCGGCAAGAAAAATGTGGTCCGGCTTCGGTTTATCCCCGCTGGCGCGGGGAACACTAATACTGATTATCTGCTAACACACGGCTCTACGGTTTATCCCCGCTGGCGCGGGGAACACTACAGTAAACCAATGCCATGCCAACATCGCTCCGGTTTATCCCCGCTGGCGCGGGGAACACTGCTACAAATGGCACTCCATTTATTATTCCGCCGGTTTATCCCCGCTGGCGCGGGGAACACCAAAGTTAGCGAGGTTTGACGCATCAACCAAACGGTTTATCCCCGCTGGCGCGGGGAACACGCCACGACGTTTGCCTGTGTCCCGATAGCCTCCGGTTTATCCCCGCTGGCGCGGGGAACACATCAGTCCGGGCGCGCAGTTTACGTCGTACCGCGGTTTATCCCCGCTGGCGCGGGGAACACGCGACGACTGAAAAATGGCGGGGTAATAAACTCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NC_022525|1|1|2931638-2933316|CRISPRCasFinder
GTGTTTATCCCCGTTGGCGCGGGGAACAT	TTTTCAGCCCTTGCCGACTGCGGAACGCCCCT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATGGATGGCTCATATCCGGTTTCTGTTTCTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCGGTAACGTCTGGATTATTTTCTGAGGGTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTGCTGCTGCTGATCAGTTTACCCGCTGGGTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTTATTACTGCTTAGTTAATTAATGGGTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGCGAATAATCTCTAATAGTCTCAATTCGTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCCGATCGATGGCAAAGTTACCGATCCCTATCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATATTCCGGAACCTGACCCGCAACTACAGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACGTCGCTGTTAATCTCCTCGTTAAGAAGCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCGACAGTTGCTCAGGTGGCTGCCGCCAAGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GACGACAAAATTAATATTGTTGGCTGGCGTGT
CGGTTTATCCCCGCTGACGCGGGGAACAC	CGTAAATTTTGCTGTAATCAACTGTGCTGTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCAGAGAATTGCCGCCAATAGAACAGCGCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTCCGCAAAGGAAGCAGAGCTGTTCTGCGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTGTCGTATATCCGTTACGCAACCCGCGTGCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTTGCCAGTGGATTTTTGGTTATCTATGTAGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGAATGCAGCCCCTCTAAAATTGTTGCCCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACTGGAGGAGAATTTGATGCAGGTGAAGCGTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAGTGGTGTTTAAGCCCGACGTCGGCAACAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTGAGTTCGGCAAGAAAAATGTGGTCCGGCTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAATACTGATTATCTGCTAACACACGGCTCTA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TACAGTAAACCAATGCCATGCCAACATCGCTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGCTACAAATGGCACTCCATTTATTATTCCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAGTTAGCGAGGTTTGACGCATCAACCAAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCCACGACGTTTGCCTGTGTCCCGATAGCCTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCAGTCCGGGCGCGCAGTTTACGTCGTACCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGACGACTGAAAAATGGCGGGGTAATAAACT
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NC_022525|1|1|2931638-2933316|CRT
GTGTTTATCCCCGTTGGCGCGGGGAACAT	TTTTCAGCCCTTGCCGACTGCGGAACGCCCCT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATGGATGGCTCATATCCGGTTTCTGTTTCTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCGGTAACGTCTGGATTATTTTCTGAGGGTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTGCTGCTGCTGATCAGTTTACCCGCTGGGTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTTATTACTGCTTAGTTAATTAATGGGTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGCGAATAATCTCTAATAGTCTCAATTCGTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCCGATCGATGGCAAAGTTACCGATCCCTATCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATATTCCGGAACCTGACCCGCAACTACAGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACGTCGCTGTTAATCTCCTCGTTAAGAAGCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCGACAGTTGCTCAGGTGGCTGCCGCCAAGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GACGACAAAATTAATATTGTTGGCTGGCGTGT
CGGTTTATCCCCGCTGACGCGGGGAACAC	CGTAAATTTTGCTGTAATCAACTGTGCTGTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCAGAGAATTGCCGCCAATAGAACAGCGCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTCCGCAAAGGAAGCAGAGCTGTTCTGCGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTGTCGTATATCCGTTACGCAACCCGCGTGCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTTGCCAGTGGATTTTTGGTTATCTATGTAGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGAATGCAGCCCCTCTAAAATTGTTGCCCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACTGGAGGAGAATTTGATGCAGGTGAAGCGTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAGTGGTGTTTAAGCCCGACGTCGGCAACAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTGAGTTCGGCAAGAAAAATGTGGTCCGGCTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAATACTGATTATCTGCTAACACACGGCTCTA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TACAGTAAACCAATGCCATGCCAACATCGCTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGCTACAAATGGCACTCCATTTATTATTCCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAGTTAGCGAGGTTTGACGCATCAACCAAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCCACGACGTTTGCCTGTGTCCCGATAGCCTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCAGTCCGGGCGCGCAGTTTACGTCGTACCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGACGACTGAAAAATGGCGGGGTAATAAACT
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NC_022525|1|1|2931699-2933316|PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATGGATGGCTCATATCCGGTTTCTGTTTCTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCGGTAACGTCTGGATTATTTTCTGAGGGTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTGCTGCTGCTGATCAGTTTACCCGCTGGGTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTTATTACTGCTTAGTTAATTAATGGGTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGCGAATAATCTCTAATAGTCTCAATTCGTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCCGATCGATGGCAAAGTTACCGATCCCTATCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATATTCCGGAACCTGACCCGCAACTACAGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACGTCGCTGTTAATCTCCTCGTTAAGAAGCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCGACAGTTGCTCAGGTGGCTGCCGCCAAGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GACGACAAAATTAATATTGTTGGCTGGCGTGT
CGGTTTATCCCCGCTGACGCGGGGAACAC	CGTAAATTTTGCTGTAATCAACTGTGCTGTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCAGAGAATTGCCGCCAATAGAACAGCGCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTCCGCAAAGGAAGCAGAGCTGTTCTGCGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTGTCGTATATCCGTTACGCAACCCGCGTGCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTTGCCAGTGGATTTTTGGTTATCTATGTAGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGAATGCAGCCCCTCTAAAATTGTTGCCCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACTGGAGGAGAATTTGATGCAGGTGAAGCGTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAGTGGTGTTTAAGCCCGACGTCGGCAACAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTGAGTTCGGCAAGAAAAATGTGGTCCGGCTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAATACTGATTATCTGCTAACACACGGCTCTA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TACAGTAAACCAATGCCATGCCAACATCGCTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGCTACAAATGGCACTCCATTTATTATTCCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAGTTAGCGAGGTTTGACGCATCAACCAAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCCACGACGTTTGCCTGTGTCCCGATAGCCTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCAGTCCGGGCGCGCAGTTTACGTCGTACCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGACGACTGAAAAATGGCGGGGTAATAAACT
CGGTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022525.1\|WP_000134246.1\|2924246_2925296_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NC_022525.1\|WP_017466176.1\|2935254_2936001_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NC_022525.1\|WP_000741649.1\|2925771_2926482_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NC_022525.1\|WP_000039870.1\|2943357_2944092_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NC_022525.1\|WP_000372384.1\|2929417_2930326_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NC_022525.1\|WP_024143962.1\|2942316_2943270_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NC_022525.1\|WP_000029738.1\|2939208_2941872_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_022525.1\|WP_000517480.1\|2926500_2926812_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NC_022525.1\|WP_001522893.1\|2927968_2929408_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NC_022525.1\|WP_000368584.1\|2937640_2939197_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NC_022525.1\|WP_000281486.1\|2934622_2935273_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NC_022525.1\|WP_001173663.1\|2927376_2927982_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NC_022525.1\|WP_000490481.1\|2930576_2931623_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NC_022525.1\|WP_001518648.1\|2933412_2933706_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NC_022525.1\|WP_017466175.1\|2933705_2934626_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NC_022525.1\|WP_001221537.1\|2923504_2924266_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NC_022525.1\|WP_017465864.1\|2927002_2927326_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NC_022525.1\|WP_000117946.1\|2937083_2937644_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NC_022525.1\|WP_001219245.1\|2925292_2925772_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NC_022525.1\|WP_000206416.1\|2936011_2937070_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843

Protein	Function_ID	Function_description	E-value
NC_022525.1\|WP_000134246.1\|2924246_2925296_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NC_022525.1\|WP_017466176.1\|2935254_2936001_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.2413e-48
NC_022525.1\|WP_000741649.1\|2925771_2926482_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	2.24126e-119
NC_022525.1\|WP_000039870.1\|2943357_2944092_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.73232e-139
NC_022525.1\|WP_000372384.1\|2929417_2930326_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NC_022525.1\|WP_024143962.1\|2942316_2943270_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NC_022525.1\|WP_000029738.1\|2939208_2941872_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NC_022525.1\|WP_000517480.1\|2926500_2926812_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.08865e-64
NC_022525.1\|WP_001522893.1\|2927968_2929408_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NC_022525.1\|WP_000368584.1\|2937640_2939197_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NC_022525.1\|WP_000281486.1\|2934622_2935273_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.11215e-74
NC_022525.1\|WP_001173663.1\|2927376_2927982_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	4.61291e-146
NC_022525.1\|WP_000490481.1\|2930576_2931623_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NC_022525.1\|WP_001518648.1\|2933412_2933706_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.1867e-62
NC_022525.1\|WP_017466175.1\|2933705_2934626_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.05302e-156
NC_022525.1\|WP_001221537.1\|2923504_2924266_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	7.64916e-147
NC_022525.1\|WP_017465864.1\|2927002_2927326_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	6.60724e-48
NC_022525.1\|WP_000117946.1\|2937083_2937644_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	8.53741e-34
NC_022525.1\|WP_001219245.1\|2925292_2925772_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	3.20925e-104
NC_022525.1\|WP_000206416.1\|2936011_2937070_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	2.35073e-131

>NC_022525.1|WP_000490481.1|2930576_2931623_+|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>NC_022525.1|WP_000372384.1|2929417_2930326_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>NC_022525.1|WP_001522893.1|2927968_2929408_-|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFNGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>NC_022525.1|WP_001173663.1|2927376_2927982_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>NC_022525.1|WP_017465864.1|2927002_2927326_-|DUF3561-family-protein
MRNSHNITFTRSDAFMVDDDATSAFPGAVVGFVSWLLALGIPFLLYGPNTLFFFLYTWPFFLALMPVSVIIGIVLHLLVKGKILFSIMFTLLAVGALFGALFIWLLG
>NC_022525.1|WP_000517480.1|2926500_2926812_-|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>NC_022525.1|WP_000741649.1|2925771_2926482_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLAISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>NC_022525.1|WP_001219245.1|2925292_2925772_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDEVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>NC_022525.1|WP_000134246.1|2924246_2925296_-|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>NC_022525.1|WP_001221537.1|2923504_2924266_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQIKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
>NC_022525.1|WP_001518648.1|2933412_2933706_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAVWLLEVRAGVYVGDTSKRIREMIWQQITQLGGVGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVENQ
>NC_022525.1|WP_017466175.1|2933705_2934626_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLNPIPLKDRTSMIFLQYGQIDVLDGAFVLINKTGVRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALDDDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRATYALLAKQYGVKWHGRNYDPKDWEMGDVVNRCISAATSCLYGISEAAILAAGYAPAIGFIHSGKPLSFVYDIADIIKFESVVPKAFEIAARHPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPESESLGDSGHRGHG
>NC_022525.1|WP_000281486.1|2934622_2935273_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTSELSPAQLLHLVERGEYVMHQWLWDLFPGSKERQFLYRREELQGAFRFFVLSQEQPAASAIFDVQTRPFAPTLSAGQTLRFNLRANPTVCKNGKRHDLLMEAKRQRKTQGDSQDIWSYQQQAALTWLARQGEQNGFTLREASVDAYRQQQIRRGKDRQMIQFSSVDYTGVLVINEPALFLQRLAQGFGKSRAFGCGMMMIKPGDDA
>NC_022525.1|WP_017466176.1|2935254_2936001_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHDLPSRSALLGLLAAALGIRRDEEERLNAFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYSLAQLQASLQHPVFPLYLGRKSHPLALPLAPQLLDGRAPDVLREAYRWYQDQFNTLKLTLPGLQNECWWEGEHDGLTANKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>NC_022525.1|WP_000206416.1|2936011_2937070_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNDNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITSLHKNMNKVYGQRTDTASFDVMNQQGSMKDVLDFICA
>NC_022525.1|WP_000117946.1|2937083_2937644_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHEELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDGDTDNEQD
>NC_022525.1|WP_000368584.1|2937640_2939197_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAETPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPLWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIWGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFADAKGARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRHYFDDHVFTNPYESSDLERIMTARKKYFTTSAEKQSAKAAKAKKQEAAE
>NC_022525.1|WP_000029738.1|2939208_2941872_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVVTENLLLFHSRFAFYDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>NC_022525.1|WP_024143962.1|2942316_2943270_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWNKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKLDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>NC_022525.1|WP_000039870.1|2943357_2944092_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG

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Crispr_ID: NC_022525_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022525_2

2949486-2950673

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

19 spacers

cas3,cas8e,cse2gr11,cas7,cas5

The CRISPR arrays of NC_022525_2

>merge|NC_022525|2|2949486-2950673|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
ACGGCTATCCTTGTTGGCGCGGGGAACACTAACTCATCACATCCGCGTCAGACCTCGTGACCGGTTTATCCCCGCTGGCGCGGGGAACACGACAACGCATCAAGACCGATATACACCACGCCCGGTTTATCCCCGCTGGCGCGGGGAACACCCGGACAACAGTGACACCTGTAAATTCTGCGCCGGTTTATCCCCGCTGGCGCGGGGAACACAGCAAACTCAGTGGCAGCGGCGGTGCAGTTTTCGGTTTATCCCCGCTGGCGCGGGGAACACAGCAAACTCAGTGGCAGCGGCGGTGCAGTTTTCGGTTTATCCCCGCTGGCGCGGGGAACACTCTACCCTATCTAACCCATTAGAATAAAAGGACGGTTTATCCCCGCTGGCGCGGGGAACACTTCTCGGCGCGGCGCAATATCCCGGCGCACGCCGGTTTATCCCCGCTGGCGCGGGGAACACCGCACCACTATGATTCGAATAGATCGTAGCGGCGGTTTATCCCCGCTGGCGCGGGAAACACAGTGCCATCATCCCACTCGCAAAGATTCAGCACGGTTTATCCCCGCTGGCGCGGGGAACACGGATATCTCTAATAAAGGTCATCTTCGTTTCCCGGTTTATCCCCGCTGGCGCGGGGAACACGTCTATAGTTCCCCGCATACTATCACCGCGGACGGTTTATCCCCGCTGGCGCGGGGAACACTAGTCGATCGGTCTGGAGCAGATAAACCGGCACGGTTTATCCCCGCTGGCGCGGGGAACACTTTGTCCAGTTCGGCGATGCGGCGTTCTGCGGCGGTTTATCCCCGCTGGCGCGGGGAACACGCTCGGGGAAGTATCAACCAGCAGATAACGGTCGGTTTATCCCCGCTGGCGCGGGGAACACTGCGAAATAGTCACGTGAGCAACGCCGACAAGCGGTTTATCCCCGCTGGCGCGGGGAACACTTACGTACTCCGGGGAAGTCGTTAGAGAGCTGCGGTTTATCCCCGCTGGCGCGGGGAACACAACTCTGACCATTGAAACGCGTGTATCCAGCACGGTTTATCCCCGCTGGCGCGGGGAACACGAATTTGTAATCTGGACTCCCATGCGTTATCACGGTTTATCCCCGCTGGCGCGGGGAACACAGTAACGTGGTAGCGCATTGCAGGATAGTATTCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NC_022525|2|2|2949486-2950673|CRISPRCasFinder
ACGGCTATCCTTGTTGGCGCGGGGAACAC	TAACTCATCACATCCGCGTCAGACCTCGTGAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GACAACGCATCAAGACCGATATACACCACGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCGGACAACAGTGACACCTGTAAATTCTGCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGCAAACTCAGTGGCAGCGGCGGTGCAGTTTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGCAAACTCAGTGGCAGCGGCGGTGCAGTTTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTACCCTATCTAACCCATTAGAATAAAAGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCTCGGCGCGGCGCAATATCCCGGCGCACGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCACCACTATGATTCGAATAGATCGTAGCGG
CGGTTTATCCCCGCTGGCGCGGGAAACAC	AGTGCCATCATCCCACTCGCAAAGATTCAGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGATATCTCTAATAAAGGTCATCTTCGTTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTATAGTTCCCCGCATACTATCACCGCGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAGTCGATCGGTCTGGAGCAGATAAACCGGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTTGTCCAGTTCGGCGATGCGGCGTTCTGCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTCGGGGAAGTATCAACCAGCAGATAACGGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGCGAAATAGTCACGTGAGCAACGCCGACAAG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTACGTACTCCGGGGAAGTCGTTAGAGAGCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACTCTGACCATTGAAACGCGTGTATCCAGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAATTTGTAATCTGGACTCCCATGCGTTATCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGTAACGTGGTAGCGCATTGCAGGATAGTATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NC_022525|2|2|2949486-2950673|CRT
ACGGCTATCCTTGTTGGCGCGGGGAACAC	TAACTCATCACATCCGCGTCAGACCTCGTGAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GACAACGCATCAAGACCGATATACACCACGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCGGACAACAGTGACACCTGTAAATTCTGCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGCAAACTCAGTGGCAGCGGCGGTGCAGTTTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGCAAACTCAGTGGCAGCGGCGGTGCAGTTTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTACCCTATCTAACCCATTAGAATAAAAGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCTCGGCGCGGCGCAATATCCCGGCGCACGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCACCACTATGATTCGAATAGATCGTAGCGG
CGGTTTATCCCCGCTGGCGCGGGAAACAC	AGTGCCATCATCCCACTCGCAAAGATTCAGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGATATCTCTAATAAAGGTCATCTTCGTTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTATAGTTCCCCGCATACTATCACCGCGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAGTCGATCGGTCTGGAGCAGATAAACCGGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTTGTCCAGTTCGGCGATGCGGCGTTCTGCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTCGGGGAAGTATCAACCAGCAGATAACGGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGCGAAATAGTCACGTGAGCAACGCCGACAAG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTACGTACTCCGGGGAAGTCGTTAGAGAGCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACTCTGACCATTGAAACGCGTGTATCCAGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAATTTGTAATCTGGACTCCCATGCGTTATCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGTAACGTGGTAGCGCATTGCAGGATAGTATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NC_022525|2|2|2949491-2949636|PILER-CR
TATCCTTGTTGGCGCGGGGAACACTAACTC	ATCACATCCGCGTCAGACCTCGTGACCGGTT
TATCCCCGCTGGCGCGGGGAACACGACAAC	GCATCAAGACCGATATACACCACGCCCGGTT
TATCCCCGCTGGCGCGGGGAACACCCGGACAACAGTGACACCTGTAAATTCTGCGCCGGTTTATCCCCGCTGGCGCGGGGAACACAGCAAACTCAGTGGCAGCGGCGGTGCAGTTTTCGGTTTATCCCCGCTGGCGCGGGGAACACAGCAAACTCAGTGGCAGCGGCGGTGCAGTTTTCGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTACCCTATCTAACCCATTAGAATAAAAGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCTCGGCGCGGCGCAATATCCCGGCGCACGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCACCACTATGATTCGAATAGATCGTAGCGG
CGGTTTATCCCCGCTGGCGCGGGAAACAC	AGTGCCATCATCCCACTCGCAAAGATTCAGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGATATCTCTAATAAAGGTCATCTTCGTTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTATAGTTCCCCGCATACTATCACCGCGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAGTCGATCGGTCTGGAGCAGATAAACCGGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTTGTCCAGTTCGGCGATGCGGCGTTCTGCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTCGGGGAAGTATCAACCAGCAGATAACGGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGCGAAATAGTCACGTGAGCAACGCCGACAAG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTACGTACTCCGGGGAAGTCGTTAGAGAGCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACTCTGACCATTGAAACGCGTGTATCCAGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAATTTGTAATCTGGACTCCCATGCGTTATCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGTAACGTGGTAGCGCATTGCAGGATAGTATT


>NC_022525|2|3|2949791-2950673|PILER-CR
	ATCACATCCGCGTCAGACCTCGTGACCGGTT
TATCCCCGCTGGCGCGGGGAACACGACAAC	GCATCAAGACCGATATACACCACGCCCGGTT
TATCCCCGCTGGCGCGGGGAACACCCGGACAACAGTGACACCTGTAAATTCTGCGCCGGTTTATCCCCGCTGGCGCGGGGAACACAGCAAACTCAGTGGCAGCGGCGGTGCAGTTTTCGGTTTATCCCCGCTGGCGCGGGGAACACAGCAAACTCAGTGGCAGCGGCGGTGCAGTTTTCGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTACCCTATCTAACCCATTAGAATAAAAGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCTCGGCGCGGCGCAATATCCCGGCGCACGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCACCACTATGATTCGAATAGATCGTAGCGG
CGGTTTATCCCCGCTGGCGCGGGAAACAC	AGTGCCATCATCCCACTCGCAAAGATTCAGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGATATCTCTAATAAAGGTCATCTTCGTTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTATAGTTCCCCGCATACTATCACCGCGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAGTCGATCGGTCTGGAGCAGATAAACCGGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTTGTCCAGTTCGGCGATGCGGCGTTCTGCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTCGGGGAAGTATCAACCAGCAGATAACGGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGCGAAATAGTCACGTGAGCAACGCCGACAAG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTACGTACTCCGGGGAAGTCGTTAGAGAGCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACTCTGACCATTGAAACGCGTGTATCCAGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAATTTGTAATCTGGACTCCCATGCGTTATCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGTAACGTGGTAGCGCATTGCAGGATAGTATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022525.1\|WP_017466176.1\|2935254_2936001_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NC_022525.1\|WP_017466162.1\|2956428_2957016_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185169
NC_022525.1\|WP_000039870.1\|2943357_2944092_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NC_022525.1\|WP_000036734.1\|2951776_2953075_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NC_022525.1\|WP_024143962.1\|2942316_2943270_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NC_022525.1\|WP_000210863.1\|2953157_2954795_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NC_022525.1\|WP_000210449.1\|2955022_2955823_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NC_022525.1\|WP_000108313.1\|2948139_2948502_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NC_022525.1\|WP_000832396.1\|2961121_2961592_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185179
NC_022525.1\|WP_017466163.1\|2945905_2947705_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NC_022525.1\|WP_000178258.1\|2960600_2961107_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185178
NC_022525.1\|WP_000368584.1\|2937640_2939197_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NC_022525.1\|WP_000206416.1\|2936011_2937070_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NC_022525.1\|WP_017466196.1\|2959807_2960581_+\|fimbria/pilus-periplasmic-chaperone	unknown	unknown	gnl\|CDD\|185177
NC_022525.1\|WP_077908752.1\|2957095_2959795_+\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|185176
NC_022525.1\|WP_001199961.1\|2950969_2951641_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NC_022525.1\|WP_017466195.1\|2961588_2962125_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185168
NC_022525.1\|WP_001290662.1\|2944193_2945906_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NC_022525.1\|WP_000029738.1\|2939208_2941872_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_022525.1\|WP_000117946.1\|2937083_2937644_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862

Protein	Function_ID	Function_description	E-value
NC_022525.1\|WP_017466176.1\|2935254_2936001_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.2413e-48
NC_022525.1\|WP_017466162.1\|2956428_2957016_+\|fimbrial-protein	gnl\|CDD\|185169	PRK15261, PRK15261, fimbrial protein SteA; Provisional.	5.39196e-99
NC_022525.1\|WP_000039870.1\|2943357_2944092_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.73232e-139
NC_022525.1\|WP_000036734.1\|2951776_2953075_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NC_022525.1\|WP_024143962.1\|2942316_2943270_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NC_022525.1\|WP_000210863.1\|2953157_2954795_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NC_022525.1\|WP_000210449.1\|2955022_2955823_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.52469e-158
NC_022525.1\|WP_000108313.1\|2948139_2948502_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
NC_022525.1\|WP_000832396.1\|2961121_2961592_+\|fimbrial-protein	gnl\|CDD\|185179	PRK15276, PRK15276, putative fimbrial subunit SteE; Provisional.	1.41178e-100
NC_022525.1\|WP_017466163.1\|2945905_2947705_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NC_022525.1\|WP_000178258.1\|2960600_2961107_+\|fimbrial-protein	gnl\|CDD\|185178	PRK15275, PRK15275, putative fimbrial protein SteD; Provisional.	1.6337e-105
NC_022525.1\|WP_000368584.1\|2937640_2939197_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NC_022525.1\|WP_000206416.1\|2936011_2937070_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	2.35073e-131
NC_022525.1\|WP_017466196.1\|2959807_2960581_+\|fimbria/pilus-periplasmic-chaperone	gnl\|CDD\|185177	PRK15274, PRK15274, putative periplasmic fimbrial chaperone protein SteC; Provisional.	0
NC_022525.1\|WP_077908752.1\|2957095_2959795_+\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|185176	PRK15273, PRK15273, fimbrial biogenesis outer membrane usher protein.	0
NC_022525.1\|WP_001199961.1\|2950969_2951641_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.43874e-155
NC_022525.1\|WP_017466195.1\|2961588_2962125_+\|fimbrial-protein	gnl\|CDD\|185168	PRK15260, PRK15260, fimbrial protein SteF; Provisional.	2.30226e-121
NC_022525.1\|WP_001290662.1\|2944193_2945906_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NC_022525.1\|WP_000029738.1\|2939208_2941872_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NC_022525.1\|WP_000117946.1\|2937083_2937644_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	8.53741e-34

>NC_022525.1|WP_000108313.1|2948139_2948502_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>NC_022525.1|WP_017466163.1|2945905_2947705_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGAVAVTPAPEGKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQATASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLIATLSVNQNITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAEALIGLLRPLTPRLYSIASAQAEVESEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRAFMQQRAADGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLNRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>NC_022525.1|WP_001290662.1|2944193_2945906_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIEKLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAELGLVGKAPGRYNVHLGGNRMGTRIPRMYRENITESEILDSVDELVGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NC_022525.1|WP_000039870.1|2943357_2944092_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NC_022525.1|WP_024143962.1|2942316_2943270_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWNKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKLDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>NC_022525.1|WP_000029738.1|2939208_2941872_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVVTENLLLFHSRFAFYDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>NC_022525.1|WP_000368584.1|2937640_2939197_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAETPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPLWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIWGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFADAKGARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRHYFDDHVFTNPYESSDLERIMTARKKYFTTSAEKQSAKAAKAKKQEAAE
>NC_022525.1|WP_000117946.1|2937083_2937644_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHEELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDGDTDNEQD
>NC_022525.1|WP_000206416.1|2936011_2937070_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNDNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITSLHKNMNKVYGQRTDTASFDVMNQQGSMKDVLDFICA
>NC_022525.1|WP_017466176.1|2935254_2936001_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHDLPSRSALLGLLAAALGIRRDEEERLNAFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYSLAQLQASLQHPVFPLYLGRKSHPLALPLAPQLLDGRAPDVLREAYRWYQDQFNTLKLTLPGLQNECWWEGEHDGLTANKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>NC_022525.1|WP_001199961.1|2950969_2951641_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMPLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>NC_022525.1|WP_000036734.1|2951776_2953075_-|phosphopyruvate-hydratase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NC_022525.1|WP_000210863.1|2953157_2954795_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
>NC_022525.1|WP_000210449.1|2955022_2955823_-|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSFPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>NC_022525.1|WP_017466162.1|2956428_2957016_+|fimbrial-protein
MKSSHFCKLAVTASLVMGIVSGAQAAGSNTAKVTFLGNIVDSPCSVTLDTEDQTVNMGSSIGNGTLSNGKTTINNARTFHIDLEGCTWATEKNMNVVFTTGSGTTAATGATDNLALMKTDGTGAISNVSLAISDAGKNNIKLGDTYTQAFADLDGDTILDEKQSLNFTAWLVGAATGTVGTGEFSSAANVTISYL
>NC_022525.1|WP_077908752.1|2957095_2959795_+|fimbrial-biogenesis-outer-membrane-usher-protein
MMNNTWKSVLCPIACGVGMLLSVSPYSASGKDIEFNTDFLDVKNRDNVNIAQFSRKGFILPGVYLLQIKINGQTLPQEFPVNWVIPEHDPQGSEVCAEPELVTQLGIKPELAEKLVWITHGERQCLAPDSLKGMDFQADLGHSTLLVNLPQAYMEYSDVDWDPPARWDNGIPGIILDYNINNQLRHDQESGSEEQSISGNGTLGANLGAWRLRADWQASYDHRDDDENTSTLHDQSWSRYYAYRALPTLGAKLTLGESYLQSDVFDSFNYIGASVISDDQMLPPKLRGYAPEIVGIARSNAKVKVSWQGRVLYETQVPAGPFRIQDLNQSVSGTLHVTVEEQNGQTQEFDVNTASVPFLTRPGMVRYKMALGRPQDWDHHPITGTFASAEASWGVTNGWSLYGGAIGESNYQAVALGSGKDLGVVGAVAVDITHSIAHMPQDDGFDGETLQGNSYRISYSRDFDEIDSRLTFAGYRFSEKNFMSMSDYLDAKTYHHLNAGHEKERYTVTYNQNFREQGMSAYFSYSRSTFWDSPDQSNYNLSLSWYFDLGSIKNLSASLNGYRSEYNGDKDDGVYISLSVPWGNDSISYNGTFNGSQHRNQLGYSGHSQNGDNWQLHVGQDEQGAQADGYYSHQGALTDIDLSADYEEGSYRSLGMSLRGGMTLTTQGGALHRGSLAGSTRLLVDTDGIADVPVSGNGSPTSTNIFGKAVIADVGSYSRSLARIDLNKLPEKAEATKSVVQITLTEGAIGYRHFDVVSGEKMMAVFRLADGDFPPFGAEVKNERQQQLGLVADDGNAWLAGVKAGETLKVFWDGAAQCEASLPPTFTPELLANALLLPCKILEGQPPTAPQKSSPLPAQPLIQEHTQTDGQPAAPVATTTQTPPIPLADNHAVNRKDME
>NC_022525.1|WP_017466196.1|2959807_2960581_+|fimbria/pilus-periplasmic-chaperone
MNKTNHFKRQALIASVLLAAPLVSHSAIVPDRTRVIFNGNENSITVTLKNGNATLPYLAQAWLEDDKFAKDTRYFTALPPLQRIEPKSDGQVKVQPLPAAASLPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAVARQVDKTHPWQTKLTLTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTAPIKGASLGSSPVVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK
>NC_022525.1|WP_000178258.1|2960600_2961107_+|fimbrial-protein
MTMLTRWKILVLLCGGFVTGTEAAGTKTVQLELHLVVTQPPPCTIGGASVEFGDVLTTKVGDASQTKPVGYSLNCDGRASDYLKLQIQGTTTTISGEQVLQTSVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNASATLVVDYQ
>NC_022525.1|WP_000832396.1|2961121_2961592_+|fimbrial-protein
MKRVLILTLLITQFACADNLTFHGKLINPPACTINNGETLEVSFGSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSANALTTNVPELGIELQQNGTVFPPGTSLTIDESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ
>NC_022525.1|WP_017466195.1|2961588_2962125_+|fimbrial-protein
MNRIFQTAGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNLVVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVLVTFQGVEDSTLPGLLALEPSSEASGFAIGVETAAQQPVSINATVGTAFVLKEGITTINLQARLQKYAGEEVMPGEFKGSATVSFEYQ

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Crispr_ID: NC_022525_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022525_3

3812770-3812872

Unclear

Consensus_repeat	Method
ATTATTCCCGATCCGGTGGACCCTG	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NC_022525_3

>merge|NC_022525|3|3812770-3812872|CRISPRCasFinder
ATTATTCCCGATCCGGTGGACCCTGTTATTCCCGATCCGGTAGACCCTGATCCAGTAGACCCGGTTATCCCTGACCCTATTATTCCCGATCCGGTGGACCCTG

>NC_022525|3|3|3812770-3812872|CRISPRCasFinder
ATTATTCCCGATCCGGTGGACCCTG	TTATTCCCGATCCGGTAGACCCTGATCCAGTAGACCCGGTTATCCCTGACCCT
ATTATTCCCGATCCGGTGGACCCTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_022525.1\|WP_000131288.1\|3817846_3820573_-\|magnesium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|237914
NC_022525.1\|WP_000106461.1\|3816143_3816824_+\|isochorismatase-family-protein	unknown	unknown	gnl\|CDD\|238494
NC_022525.1\|WP_017466070.1\|3802859_3804569_+\|AsmA-family-protein	unknown	unknown	gnl\|CDD\|282957
NC_022525.1\|WP_017466071.1\|3797797_3799879_+\|ATP-dependent-DNA-helicase-RecG	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236794
NC_022525.1\|WP_001068436.1\|3797102_3797792_+\|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH	unknown	unknown	gnl\|CDD\|236837
NC_022525.1\|WP_000280481.1\|3794986_3797098_+\|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis-pyrophosphate-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236843
NC_022525.1\|WP_000135058.1\|3794692_3794968_+\|DNA-directed-RNA-polymerase-subunit-omega	unknown	unknown	gnl\|CDD\|188073
NC_022525.1\|WP_001278062.1\|3814502_3815360_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|226233
NC_022525.1\|WP_000462250.1\|3799914_3801120_-\|sodium/glutamate-symporter	unknown	unknown	gnl\|CDD\|129314
NC_022525.1\|WP_001065324.1\|3817052_3817532_-\|membrane-protein	unknown	unknown	unknown
NC_022525.1\|WP_000749540.1\|3822938_3823880_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|182167
NC_022525.1\|WP_001521985.1\|3814027_3814492_-\|hypothetical-protein	unknown	unknown	unknown
NC_022525.1\|WP_001541135.1\|3815412_3815526_-\|hypothetical-protein	unknown	unknown	unknown
NC_022525.1\|WP_000115428.1\|3801347_3802739_+\|xanthine/proton-symporter-XanP	unknown	unknown	gnl\|CDD\|273276
NC_022525.1\|WP_017466068.1\|3807001_3808384_-\|glycoside-pentoside-hexuronide-family-transporter	unknown	unknown	gnl\|CDD\|183145
NC_022525.1\|WP_000535970.1\|3821993_3822896_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NC_022525.1\|WP_001082117.1\|3817732_3817825_-\|protein-MgtR	unknown	unknown	unknown
NC_022525.1\|WP_000392694.1\|3820792_3821488_-\|MgtC-family-protein	unknown	unknown	gnl\|CDD\|185283
NC_022525.1\|WP_017466069.1\|3804671_3806990_-\|alpha-xylosidase	unknown	unknown	gnl\|CDD\|236731
NC_022525.1\|WP_017465918.1\|3810388_3811006_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225360

Protein	Function_ID	Function_description	E-value
NC_022525.1\|WP_000131288.1\|3817846_3820573_-\|magnesium-translocating-P-type-ATPase	gnl\|CDD\|237914	PRK15122, PRK15122, magnesium-transporting ATPase; Provisional.	0
NC_022525.1\|WP_000106461.1\|3816143_3816824_+\|isochorismatase-family-protein	gnl\|CDD\|238494	cd01012, YcaC_related, YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. Multimerisation interface seems not to be conserved in all members.	3.05871e-58
NC_022525.1\|WP_017466070.1\|3802859_3804569_+\|AsmA-family-protein	gnl\|CDD\|282957	pfam05170, AsmA, AsmA family. The AsmA gene, whose product is involved in the assembly of outer membrane proteins in Escherichia coli. AsmA mutations were isolated as extragenic suppressors of an OmpF assembly mutant. AsmA may have a role in LPS biogenesis.	9.11295e-22
NC_022525.1\|WP_017466071.1\|3797797_3799879_+\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NC_022525.1\|WP_001068436.1\|3797102_3797792_+\|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH	gnl\|CDD\|236837	PRK11081, PRK11081, tRNA guanosine-2'-O-methyltransferase; Provisional.	2.80076e-177
NC_022525.1\|WP_000280481.1\|3794986_3797098_+\|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis-pyrophosphate-3'-pyrophosphohydrolase	gnl\|CDD\|236843	PRK11092, PRK11092, bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase.	0
NC_022525.1\|WP_000135058.1\|3794692_3794968_+\|DNA-directed-RNA-polymerase-subunit-omega	gnl\|CDD\|188073	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit. This small component of highly purified E. coli RNA polymerase is not required for transcription, but acts in assembly and is present in stochiometric amounts. The trusted cutoff excludes archaeal homologs but captures some organellar sequences. [Transcription, DNA-dependent RNA polymerase].	4.81124e-23
NC_022525.1\|WP_001278062.1\|3814502_3815360_-\|transcriptional-regulator	gnl\|CDD\|226233	COG3710, CadC, DNA-binding winged-HTH domains [Transcription].	6.25098e-40
NC_022525.1\|WP_000462250.1\|3799914_3801120_-\|sodium/glutamate-symporter	gnl\|CDD\|129314	TIGR00210, Sodium/glutamate_symport_carrier_protein, sodium--glutamate symport carrier (gltS). [Transport and binding proteins, Amino acids, peptides and amines].	0
NC_022525.1\|WP_000749540.1\|3822938_3823880_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|182167	PRK09956, PRK09956, ISNCY family transposase.	1.67877e-146
NC_022525.1\|WP_017466069.1\|3804671_3806990_-\|alpha-xylosidase	gnl\|CDD\|236731	PRK10658, PRK10658, putative alpha-glucosidase; Provisional.	0
NC_022525.1\|WP_000115428.1\|3801347_3802739_+\|xanthine/proton-symporter-XanP	gnl\|CDD\|273276	TIGR00801, Uric_acid_permease, uracil-xanthine permease. The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40) Most of the functionally characterized members of the NCS2 family are transporters specific for nucleobases including both purines and pyrimidines. However, two closely related rat members of the family, SVCT1 and SVCT2, localized to different tissues of the body, cotransport L-ascorbate and Na+ with a high degree of specificity and high affinity for the vitamin. The NCS2 family appears to be distantly related to the NCS1 family (TC #2.A.39). [Transport and binding proteins, Nucleosides, purines and pyrimidines].	2.19228e-145
NC_022525.1\|WP_017466068.1\|3807001_3808384_-\|glycoside-pentoside-hexuronide-family-transporter	gnl\|CDD\|183145	PRK11462, PRK11462, putative transporter; Provisional.	0
NC_022525.1\|WP_000535970.1\|3821993_3822896_+\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.62239e-50
NC_022525.1\|WP_000392694.1\|3820792_3821488_-\|MgtC-family-protein	gnl\|CDD\|185283	PRK15385, PRK15385, MgtC family protein.	6.81515e-155
NC_022525.1\|WP_017465918.1\|3810388_3811006_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225360	COG2771, CsgD, DNA-binding HTH domain-containing proteins [Transcription].	0.00142104

>NC_022525.1|WP_017465918.1|3810388_3811006_+|helix-turn-helix-transcriptional-regulator
MMRKPSQIVHCISCDLSCQLFPDSAVRVQYCHNAAFSIWPDGNAFLKKGFIEKLLLDRHNHLSNGFIFVDFSFPNLRRFTDLQWADSLADSGMHIVLISDRSLTPLANYWILKSNKIQGIIYSDDDDIVQQQKMHRLFTGRLANSKRGRTLNYTEFILLKRFVSGISIQQIVNIDNIDIKKLYVHKLRLENKLGHSIHKIISNIL
>NC_022525.1|WP_017466068.1|3807001_3808384_-|glycoside-pentoside-hexuronide-family-transporter
MKSEILSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDIFGIPAGFVGTMFLLARALDAISDPCMGLLADRTRSRWGKFRPWVLFGALPFGIVCVLAYSTPDLSLNGKMIYAAITYTLLTLLYTVVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGMLSTVLMMPLVKLIGGENKALGFQGGIAALSVVAFLMLAFCFFTTKERVEAPATHTSMREDLRDIWHNDQWRIVGLLTILNILAVCVRGGAMMYYVTWILGKPGVFVAFLTTYCVGNLIGSALAKPLTDWKCKVSVFWWTNALLAVISVAMFFVPMHATIAMFIFIFVIGVLHQLVTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLALGGALIGWMLAGGGYDAAAKTQNSATISIIIALFTIVPAICYLLSAAIAKRYYTLKSPFLKTILEQLAQGAHRNEQEFTHKELQN
>NC_022525.1|WP_017466069.1|3804671_3806990_-|alpha-xylosidase
MKISDGNWLIQPGLNLIHPVQVFDVEQHGNEMVVYAAPRDVRERTWQLDTPLFTLRFFSPQEGVIGVRMEHFQGALDNGPHYPLNVLQDINVEMQNNAEFAELKSGSLSVRVTKGELWSLDFLRNGVRITGSQLKNNGYVQDTNSGRNYMFERLDLGVGETVYGLGERFTALVRNGQTVETWNRDGGTSTEQSYKNIPFYITNRGYGVLVNHPQCVSFEIGSEKVSKVQFSVESEYLEYFVIDGPTPKDVLNRYTQFTGRPALPPAWSFGLWLTTSFTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPVTFPDPKGMIRRLKAKGLKVCVWINPYIGQKSPVFQELKEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNPQACEWYADKLKGLVEMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWNVLKETVGVEEAVLFARSASVGAQQFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFWSHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTEQKCRMMPYLYREAARANEAGTPMMRAMMLEFPDDPACDYLDRQYMLGDAVMVAPVFSEAGDVEFYLPEGRWTHLWRNDEVQGSRWHKQQHDFLSLPVYVRDNTLLALGNNSQKPDYAWHEGTAFQLFHLDDGCEAVCEVPATDGSTIFTLQAKRTGSTITVSGEGEARNWTLCLRNITQISGTKCGSYAESELGVVITPQGNEVVITL
>NC_022525.1|WP_017466070.1|3802859_3804569_+|AsmA-family-protein
MKLIGRLLLYVLIACLVVIFGFYFLLQTRWGADHISNWVSENSGYHLTFDVMDHRFSAPSHLLLENVTFGRDGQPATLVAKTVDIGLSIRQLTAPLHVDTILLQDGTLNISVQTAPFPFEADRLQLRNMALNSPGSEWRLSAQRVNGGVMPWRPEAGRVLGNKAQIQLSAGSLTLNDVPATNVLIEGSIDHNQVMLNTVGADMARGALTGVARRNADGSWVVENLRLNDIRLQSDKSLSEFFAPLTTVPSLQIGRLEVTDSSLQGPGWAVTDLDLSLRNLTLRKEDWQSQEGKLSMNASEFIYGSLHLLDPILNAEFSPQGVALRQFTTRWEGGMVRTSGAWLREGKALILDDTAIAGLEYTLPENWKQLWMKPLPDWLNSLTLKKFSASRNLVIDIDPAFPWQITALDGYGANLELVQHHQWGVWSGNATLNAAAATFNRVDVRRPSLSLTANASTVNISDLSAFTGKGILEATASVSQLPQRQTQISLNGRGVPMDVLQQWGWPALPIAGDGNIQLTASGNIQADAPLKPTVNGQLHAVNAQKQQITQTMQAGVVSGGEVTSTEPAL
>NC_022525.1|WP_000115428.1|3801347_3802739_+|xanthine/proton-symporter-XanP
MSVNAIEPADAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQGTSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVLSRILHLARRIITPLVSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLAIIILLNRQRNPYLRVASLVIAMAAGYLLAWFMGMLPENNAPVSQDILMVPTPLYYGLGIDWNLLLPLMLVFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIAASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPQILQFAPEWVKNLLSSGIAAGGITAIVLNLILPPEKP
>NC_022525.1|WP_000462250.1|3799914_3801120_-|sodium/glutamate-symporter
MFELDTLSTLVAATLVLLLGRKLVQSVSLLKKYTIPEPVAGGLLVAVALLVLKKSVGWEVNFDMTLRDPLMLAFFATIGLNANLASLRKGGRVVGVFLVVVVGLLLMQNAIGIGMASLLGLDPLMGLIAGSITLSGGHGTGAAWSKLFVERYGFANATEVAMACATFGLVLGGLIGGPVARYLVKHSTTPDGMPDDQAVPTAFEKPDVGRMITSLVLIETIALIAICLTVGKIVAQLLAGTVLELPVFVCVLFVGVILSNGLALVGFYRVFERAVSVLGNVSLSLFLAMALMSLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYDAAVLAAGHCGFGLGATPTAIANMQAITDRFGPSHMAFLVVPMVGAFFIDIVNALVIKLYLMLPIFAQ
>NC_022525.1|WP_017466071.1|3797797_3799879_+|ATP-dependent-DNA-helicase-RecG
MSGRLLDAVPLNSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIGELLPGIYATVEGEVLNCNITFGGRRMMTCQISDGSGILTMRFFNFNAAMKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRLQGDLSTPELQETLTPVYPTTEGVKQATLRKLTDQALELLDTCAIAELLPPELAQGMMSLPEALRTLHRPPPTLQLADLETGKHPAQRRLILEELLAHNLSMLALRAGAQRYHAQPLSTNNILKDKLLASLPFKPTSAQARVVAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHANNFRNWFEPLGVEVGWLAGKQKGKARQAQQEAIASGQVQMIVGTHAIFQEQVQFNGLALVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRHEIIDRVRNACTTEGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFKQGELQLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKSPLSKTAQKRLQILRDSNDGFVIAQKDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEIQRIARHIHERYPQQAQALIERWMPETERYSNA
>NC_022525.1|WP_001068436.1|3797102_3797792_+|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH
MNPKRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAIWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGRGMQILATHLSDKAVDFREIDYTRPTCILMGQEKTGITQEALDLADRDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEDEQQRLLFEGGYPVLAKVAKRKGLPYPRVNQQGEIDADADWWATMQAAG
>NC_022525.1|WP_000280481.1|3794986_3797098_+|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis-pyrophosphate-3'-pyrophosphohydrolase
MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEPYITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSKLDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIARETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILSEIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVHDSDTCYRVLGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMGVAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLSSGQTVEIITAPGARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLAEIPQENIQRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQQGEAVVPTVAQSNHGHLPIKGADGVLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETEQEFITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSTFIRLTARDRVHLANIMRKIRVMPDVIKVTRNRN
>NC_022525.1|WP_000135058.1|3794692_3794968_+|DNA-directed-RNA-polymerase-subunit-omega
MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
>NC_022525.1|WP_001521985.1|3814027_3814492_-|hypothetical-protein
MLACLTLLFLGVGLGHLFHLYTEKNRDPEKCTAPVIVFYNNTQANLTLDFMYSLKKRTGVVSISGTYYVDNKMSGVIRRDVSYVWSENKDSTHFISTDINKVTRDETLSDAVIETVLPDFYVYPGKSISYTILTQGHRGFMFTIGKRPIFFCTH
>NC_022525.1|WP_001278062.1|3814502_3815360_-|transcriptional-regulator
MSCYAATASDYTQWCLLTLSNYVMFWHGNNAMLWIINDNIEFNPEMNRLASLSRPDLNIILTTPASRCLRLLLENAPSVVSQQTFFQKVWEEDGMVVSANTLYQNISIIRRGLRTVGENEDTLIITVPRRGFQIEPGVSLMTIRKDFAQAIEKKGETPPRMSGRWFKHYVPVLWMTGTFAVGILLGTISWQTVPDKDFYDRYTLVETTQGCHFFSRNEDIESGSRFASYKSMILKTGMDCQKYPWVYFPSSSRTPAVTALICQQPYKTRGDTGCVTLFFRGVTHG
>NC_022525.1|WP_001541135.1|3815412_3815526_-|hypothetical-protein
MIFSPQYKTGDLTNKKTKRTFTPESAIMRKAVSTLTC
>NC_022525.1|WP_000106461.1|3816143_3816824_+|isochorismatase-family-protein
MSTPANFNGQRPAIDANDAVMLLIDHQSGLFQTVGDMPMPELRARAAALAKIATLCNMPVITTASVPQGPNGPLIPEIHANAPHAQYVARKGEINAWDNADFVQAVKATGRKTLIIAGTITSVCMAFPAISAVAEGYKVFAVIDASGTYSKMAQEITMARVVQAGVVPMDTAAVASELQRTWNREDAAEWADVYTKIFPAYQLLIESYTKAQEVVKNNELLDSQRA
>NC_022525.1|WP_001065324.1|3817052_3817532_-|membrane-protein
MNNRRGLTAVLATLITFSLSATPVLANPGNGNGGGHGNNAANQGNNGNGHKGNAGQKTEHRKNGGKPDHVESDISYAVARQLAVNLGLTGYQSLPPGIAKNLARGKPLPPGIAKKTVPASMLGQLPYYPGYEWKIVGDNLVLIALSTAVVTAIINGVFD
>NC_022525.1|WP_001082117.1|3817732_3817825_-|protein-MgtR
MNRSPDKIIALIFLLISLLVLCLALWQIVF
>NC_022525.1|WP_000131288.1|3817846_3820573_-|magnesium-translocating-P-type-ATPase
MTDMNIENRKLNRPASENDKQHKKVFPIEAEAFHSPEETLARLNSHRQGLTIEEASERLKVYGRNEVAHEQVPPALIQLLQAFNNPFIYVLMALAGVSFITDYWLPLRRGEETDLTGVLIILTMVSLSGLLRFWQEFRTNRAAQALKKMVRTTATVLRRGPGNIGAVQEEIPIEELVPGDVVFLAAGDLVPADVRLLASRDLFISQSILSGESLPVEKYDVMADVAGKDSEQLPDKDKSLLDLGNICLMGTNVTSGRAQAVVVATGSRTWFGSLAKSIVGTRTQTAFDRGVNSVSWLLIRFMLIMVPVVLLINGFSKGDWVEASLFALAVAVGLTPEMLPMIVSSNLAKGAIAMSRRKVIVKRLNAIQNFGAMDVLCTDKTGTLTQDNIFLEHHLDVSGVKSSRVLMLAWLNSSSQSGARNVMDRAILRFGEGRIAPSTKARFIKRDELPFDFVRRRVSVLVEDAQHGDRCLICKGAVEEMMMVATHLREGDRVVALTETRRELLLAKTEDYNAQGFRVLLIATRKLDGSGNNPTLSVEDETELTIEGMLTFLDPPKESAGKAIAALRDNGVAVKVLTGDNPVVTARICLEVGIDTHDILTGTQVEAMSDAELASEVEKRAVFARLTPLQKTRILQALQKNGHTVGFLGDGINDAPALRDADVGISVDSAADIAKESSDIILLEKDLMVLEEGVIKGRETFGNIIKYLNMTASSNFGNVFSVLVASAFIPFLPMLAIHLLIQNLMYDISQLSLPWDKMDKEFLRKPRKWDAKNIGRFMLWIGPTSSIFDITTFALMWYVFAANNVEAQALFQSGWFIEGLLSQTLVVHMLRTQKIPFIQSRATLPVLLTTGLIMAIGIYIPFSPLGAMVGLEPLPLSYFPWLVATLLSYCLVAQGMKRFYIKRFGQWF
>NC_022525.1|WP_000392694.1|3820792_3821488_-|MgtC-family-protein
MEERMLMFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGVIMREGMNVRGLNTAATLWCSAGIGVLCGLGQFKNALAATIIILCANILLREAAQRINQLPISAEGEKRYILKVTCNKEDESAVRQWLLNIVKEAAICLQGLGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ
>NC_022525.1|WP_000535970.1|3821993_3822896_+|EamA-family-transporter
MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSRMSSQFLTMIRLLFAGLILVTFSFMHGDKIFSILKNRKDALSLLIFSVVGALTVQLTFLLTIEKSNAATATVLQFLSPTIIVAWFALARRTRPGILVLTAILTSLIGTFLLVTHGNPTSLSISSGALFWGIASAFAAAFYTTWPSRLIAQYGTLPVVGWSMSFGGLILLPFYAKEGTHFAVSGSLILAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGISFTLPDWLGTLLILSSVILISLDSRRRARAA
>NC_022525.1|WP_000749540.1|3822938_3823880_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MKKSPTSTPHDAVFKTFLRHPDTARDFLNIHLPHSLRIRCDLTTLKLAPDSFIEKNLRAFYSDVLWSLKTCEGDGYIYVVIEHQSTPDAHMAFRLMRYATAAMQRHLDAGHKTLPLVIPMLFYHGAKSPYPFSLCWLDEFDDPALARQLYATAFPLVDITVVPDNEIMQHRRIAMLELVQKHIRQRDLMGLVERLAVLLITGNANDSQLKALFNYLLIQHGSTPRFGKFIREVARRVPQHKERLMTIVDRIRESGRRKGKREGVQQGIQQGIHQGKQEEALRIAHTMLEQGIEREMVLMITGLSDEEIKAKRH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_022525_1	1.24\|2933073\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2933073-2933104	32	NZ_KU963390	Escherichia coli strain ECO37 plasmid ECO37P2, complete sequence	11380-11411	0	1.0
NC_022525_1	1.24\|2933073\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2933073-2933104	32	NZ_KU963390	Escherichia coli strain ECO37 plasmid ECO37P2, complete sequence	51216-51247	0	1.0
NC_022525_1	1.24\|2933073\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2933073-2933104	32	NZ_CP010193	Escherichia coli strain M8 plasmid B, complete genome	13579-13610	0	1.0
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_CP010173	Escherichia coli strain H8 plasmid A, complete sequence	43964-43995	2	0.938
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_CP021729	Escherichia coli strain Combat11I9 plasmid pCombat11I9-3, complete sequence	74371-74402	2	0.938
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_CP046005	Escherichia coli strain 1919D3 plasmid p1919D3-2, complete sequence	16994-17025	2	0.938
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	MG592476	Vibrio phage 1.104.O._10N.286.49.A12, partial genome	53386-53417	2	0.938
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	MG592538	Vibrio phage 1.171.O._10N.261.52.F12, partial genome	52140-52171	2	0.938
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	MG592428	Vibrio phage 1.046.O._10N.286.52.E3, partial genome	57590-57621	2	0.938
NC_022525_1	1.22\|2932951\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932951-2932982	32	NZ_CP041251	Raoultella electrica strain DSM 102253 plasmid unnamed4, complete sequence	4814-4845	4	0.875
NC_022525_1	1.24\|2933073\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2933073-2933104	32	NC_011148	Salmonella enterica subsp. enterica serovar Agona str. SL483 plasmid, complete sequence	16491-16522	4	0.875
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	CP054337	Escherichia coli strain SCU-120 plasmid pSCU-120-2, complete sequence	29797-29828	4	0.875
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_CP021537	Escherichia coli strain AR_0119 plasmid unitig_3, complete sequence	42949-42980	4	0.875
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_CP026938	Escherichia coli strain CFS3292 plasmid pCFS3292-3, complete sequence	78817-78848	4	0.875
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_MH844525	Escherichia coli strain SCEC128 plasmid pSCEC128, complete sequence	28593-28624	4	0.875
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_MH580301	Escherichia coli strain 1107 plasmid p1107-99K, complete sequence	9058-9089	4	0.875
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_CP042508	Leclercia adecarboxylata strain E1 plasmid pE1_003, complete sequence	12322-12353	4	0.875
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_CP040893	Leclercia adecarboxylata strain Z96-1 plasmid pZ96-1_2, complete sequence	56847-56878	4	0.875
NC_022525_1	1.2\|2931728\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2931728-2931759	32	NZ_CP022304	Thalassococcus sp. S3 plasmid pS3A, complete sequence	1984-2015	5	0.844
NC_022525_1	1.18\|2932707\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932707-2932738	32	NC_021559	Prochlorococcus phage P-SSM3 genomic sequence	102367-102398	5	0.844
NC_022525_1	1.2\|2931728\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2931728-2931759	32	NZ_CP023072	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666a, complete sequence	328890-328921	6	0.812
NC_022525_1	1.18\|2932707\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932707-2932738	32	MN694803	Marine virus AFVG_250M814, complete genome	36099-36130	6	0.812
NC_022525_1	1.24\|2933073\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2933073-2933104	32	NC_017903	Escherichia coli Xuzhou21 plasmid pO157_Sal, complete sequence	7494-7525	6	0.812
NC_022525_1	1.10\|2932217\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932217-2932248	32	MH651182	Gordonia phage Neville, complete genome	14047-14078	7	0.781
NC_022525_2	2.2\|2949576\|32\|NC_022525\|CRISPRCasFinder,CRT	2949576-2949607	32	MF495478	Aeromonas salmonicida plasmid pS121-1b, complete sequence	117450-117481	7	0.781
NC_022525_2	2.2\|2949576\|32\|NC_022525\|CRISPRCasFinder,CRT	2949576-2949607	32	NZ_CP038450	Aeromonas media strain R50-22 plasmid pAeme6, complete sequence	31198-31229	7	0.781
NC_022525_2	2.2\|2949576\|32\|NC_022525\|CRISPRCasFinder,CRT	2949576-2949607	32	NZ_CP022170	Aeromonas salmonicida strain S121 plasmid pS121-1a, complete sequence	125043-125074	7	0.781
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NC_017385	Ketogulonicigenium vulgare WSH-001 plasmid 2, complete sequence	198251-198282	7	0.781
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_CP012910	Ketogulonicigenium vulgare strain Hbe602 plasmid 2, complete sequence	46733-46764	7	0.781
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NC_014626	Ketogulonicigenium vulgare Y25 plasmid pYP12, complete sequence	6403-6434	7	0.781
NC_022525_2	2.12\|2950186\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950186-2950217	32	NZ_CP006990	Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence	478474-478505	7	0.781
NC_022525_2	2.12\|2950186\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950186-2950217	32	NZ_CP013556	Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence	716796-716827	7	0.781
NC_022525_2	2.12\|2950186\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950186-2950217	32	NZ_CP020911	Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence	633092-633123	7	0.781
NC_022525_2	2.12\|2950186\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950186-2950217	32	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	493788-493819	7	0.781
NC_022525_2	2.12\|2950186\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950186-2950217	32	NZ_CP013567	Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence	716796-716827	7	0.781
NC_022525_2	2.12\|2950186\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950186-2950217	32	NZ_CP021127	Rhizobium sp. Kim5 plasmid pRetKim5c, complete sequence	443317-443348	7	0.781
NC_022525_2	2.13\|2950247\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950247-2950278	32	KX657793	Mycobacterium phage DarthPhader, complete genome	27141-27172	7	0.781
NC_022525_2	2.20\|2949521\|31\|NC_022525\|PILER-CR	2949521-2949551	31	JX434031	Pseudomonas phage JBD24, complete genome	2243-2273	7	0.774
NC_022525_2	2.21\|2949582\|31\|NC_022525\|PILER-CR	2949582-2949612	31	MF495478	Aeromonas salmonicida plasmid pS121-1b, complete sequence	117451-117481	7	0.774
NC_022525_2	2.21\|2949582\|31\|NC_022525\|PILER-CR	2949582-2949612	31	NZ_CP022170	Aeromonas salmonicida strain S121 plasmid pS121-1a, complete sequence	125044-125074	7	0.774
NC_022525_2	2.21\|2949582\|31\|NC_022525\|PILER-CR	2949582-2949612	31	NZ_CP038450	Aeromonas media strain R50-22 plasmid pAeme6, complete sequence	31198-31228	7	0.774
NC_022525_1	1.11\|2932278\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932278-2932309	32	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	290305-290336	8	0.75
NC_022525_1	1.13\|2932400\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932400-2932431	32	NZ_CP049029	Fluviibacterium aquatile strain SC52 plasmid pSC52_1, complete sequence	198521-198552	8	0.75
NC_022525_1	1.23\|2933012\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2933012-2933043	32	NZ_CP024786	Nostoc flagelliforme CCNUN1 plasmid pNFSY01, complete sequence	14571-14602	8	0.75
NC_022525_1	1.23\|2933012\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2933012-2933043	32	NZ_CP026687	Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM5, complete sequence	3635-3666	8	0.75
NC_022525_2	2.1\|2949515\|32\|NC_022525\|CRISPRCasFinder,CRT	2949515-2949546	32	JX434031	Pseudomonas phage JBD24, complete genome	2242-2273	8	0.75
NC_022525_2	2.2\|2949576\|32\|NC_022525\|CRISPRCasFinder,CRT	2949576-2949607	32	NZ_CP048109	Klebsiella michiganensis strain BD177 plasmid unnamed1	11553-11584	8	0.75
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	NZ_HG938354	Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence	227163-227194	8	0.75
NC_022525_2	2.4\|2949698\|32\|NC_022525\|CRISPRCasFinder,CRT	2949698-2949729	32	NZ_CP017759	Cupriavidus necator strain NH9 plasmid pENH92, complete sequence	48479-48510	8	0.75
NC_022525_2	2.5\|2949759\|32\|NC_022525\|CRISPRCasFinder,CRT	2949759-2949790	32	NZ_CP017759	Cupriavidus necator strain NH9 plasmid pENH92, complete sequence	48479-48510	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448563	Streptococcus satellite phage Javan601, complete genome	3004-3035	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448565	Streptococcus satellite phage Javan603, complete genome	3286-3317	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448571	Streptococcus satellite phage Javan609, complete genome	3004-3035	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448575	Streptococcus satellite phage Javan612, complete genome	3004-3035	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448567	Streptococcus satellite phage Javan605, complete genome	3004-3035	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448574	Streptococcus satellite phage Javan611, complete genome	2668-2699	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448578	Streptococcus satellite phage Javan615, complete genome	2609-2640	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448577	Streptococcus satellite phage Javan614, complete genome	2586-2617	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448573	Streptococcus satellite phage Javan610, complete genome	3036-3067	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448568	Streptococcus satellite phage Javan606, complete genome	3004-3035	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448570	Streptococcus satellite phage Javan608, complete genome	3036-3067	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448564	Streptococcus satellite phage Javan602, complete genome	3286-3317	8	0.75
NC_022525_2	2.6\|2949820\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949820-2949851	32	MK448566	Streptococcus satellite phage Javan604, complete genome	3004-3035	8	0.75
NC_022525_2	2.14\|2950308\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950308-2950339	32	MN693945	Marine virus AFVG_250M952, complete genome	30837-30868	8	0.75
NC_022525_2	2.14\|2950308\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950308-2950339	32	MT773554	Myoviridae sp. isolate BML_2 genomic sequence	32798-32829	8	0.75
NC_022525_2	2.21\|2949582\|31\|NC_022525\|PILER-CR	2949582-2949612	31	NZ_CP048109	Klebsiella michiganensis strain BD177 plasmid unnamed1	11554-11584	8	0.742
NC_022525_1	1.2\|2931728\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2931728-2931759	32	NZ_CP049157	Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence	1929932-1929963	9	0.719
NC_022525_1	1.2\|2931728\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2931728-2931759	32	NZ_CP049317	Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence	1709399-1709430	9	0.719
NC_022525_1	1.11\|2932278\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932278-2932309	32	NZ_CP017833	Butyrivibrio hungatei strain MB2003 plasmid pNP6, complete sequence	3577-3608	9	0.719
NC_022525_1	1.15\|2932522\|33\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932522-2932554	33	NC_014825	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL02, complete sequence	201147-201179	9	0.727
NC_022525_1	1.18\|2932707\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932707-2932738	32	MN693670	Marine virus AFVG_250M508, complete genome	3528-3559	9	0.719
NC_022525_1	1.18\|2932707\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932707-2932738	32	MN693662	Marine virus AFVG_250M383, complete genome	3578-3609	9	0.719
NC_022525_1	1.18\|2932707\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932707-2932738	32	MN694314	Marine virus AFVG_250M513, complete genome	34322-34353	9	0.719
NC_022525_1	1.23\|2933012\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2933012-2933043	32	NZ_CP054718	Salmonella enterica strain 85-0120 plasmid unnamed2, complete sequence	64408-64439	9	0.719
NC_022525_1	1.23\|2933012\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2933012-2933043	32	NZ_CP054718	Salmonella enterica strain 85-0120 plasmid unnamed2, complete sequence	88752-88783	9	0.719
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	1162182-1162213	9	0.719
NC_022525_2	2.9\|2950003\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950003-2950034	32	MN694334	Marine virus AFVG_250M1054, complete genome	5152-5183	9	0.719
NC_022525_2	2.13\|2950247\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950247-2950278	32	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	1179902-1179933	9	0.719
NC_022525_1	1.18\|2932707\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2932707-2932738	32	MN694051	Marine virus AFVG_250M33, complete genome	34372-34403	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349325	Cyanophage S-RIM12 isolate W1_24_0910, complete genome	14478-14509	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349322	Cyanophage S-RIM12 isolate Sn_31_0910, complete genome	14481-14512	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349320	Cyanophage S-RIM12 isolate RW_29_1109, complete genome	14619-14650	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349310	Cyanophage S-RIM12 isolate RW_01_0310, complete genome	14374-14405	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349321	Cyanophage S-RIM12 isolate Sn_07_0910, complete genome	14374-14405	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349324	Cyanophage S-RIM12 isolate W1_12_0610, complete genome	14571-14602	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349314	Cyanophage S-RIM12 isolate RW_07_1112, complete genome	14619-14650	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349316	Cyanophage S-RIM12 isolate RW_22_0110, complete genome	14619-14650	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KJ019063	Synechococcus phage ACG-2014c isolate Syn7803C97, complete genome	164294-164325	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KJ019027	Synechococcus phage ACG-2014c isolate Syn7803C43, complete genome	166603-166634	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349315	Cyanophage S-RIM12 isolate RW_14_0101, complete genome	14625-14656	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349317	Cyanophage S-RIM12 isolate RW_25_0210, complete genome	14625-14656	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	NC_019444	Synechococcus phage S-MbCM6, complete genome	166612-166643	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KJ019128	Synechococcus phage ACG-2014c isolate Syn7803US88, complete genome	166709-166740	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	NC_015285	Prochlorococcus phage Syn33, complete genome	14618-14649	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349309	Cyanophage S-RIM12 isolate Np_22_1112, complete genome	14613-14644	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349319	Cyanophage S-RIM12 isolate RW_28_1109, complete genome	14604-14635	10	0.688
NC_022525_2	2.3\|2949637\|32\|NC_022525\|CRISPRCasFinder,CRT	2949637-2949668	32	KX349318	Cyanophage S-RIM12 isolate RW_27_0310, complete genome	14685-14716	10	0.688
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_CP010682	Phaeobacter piscinae strain P14 plasmid pP14_a, complete sequence	38809-38840	10	0.688
NC_022525_2	2.7\|2949881\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2949881-2949912	32	NZ_CP010644	Phaeobacter piscinae strain P36 plasmid pP36_a, complete sequence	38859-38890	10	0.688
NC_022525_2	2.13\|2950247\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950247-2950278	32	NZ_KU140623	Sinorhizobium sp. M14 plasmid pSinB, complete sequence	129526-129557	10	0.688
NC_022525_2	2.15\|2950369\|32\|NC_022525\|CRISPRCasFinder,CRT,PILER-CR	2950369-2950400	32	MN694012	Marine virus AFVG_250M887, complete genome	22169-22200	10	0.688
NC_022525_1	1.1\|2931667\|32\|NC_022525\|CRISPRCasFinder,CRT	2931667-2931698	32	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	47822-47853	11	0.656

1. spacer 1.24|2933073|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KU963390 (Escherichia coli strain ECO37 plasmid ECO37P2, complete sequence) position: , mismatch: 0, identity: 1.0

caaagttagcgaggtttgacgcatcaaccaaa	CRISPR spacer
caaagttagcgaggtttgacgcatcaaccaaa	Protospacer
********************************

2. spacer 1.24|2933073|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KU963390 (Escherichia coli strain ECO37 plasmid ECO37P2, complete sequence) position: , mismatch: 0, identity: 1.0

caaagttagcgaggtttgacgcatcaaccaaa	CRISPR spacer
caaagttagcgaggtttgacgcatcaaccaaa	Protospacer
********************************

3. spacer 1.24|2933073|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010193 (Escherichia coli strain M8 plasmid B, complete genome) position: , mismatch: 0, identity: 1.0

caaagttagcgaggtttgacgcatcaaccaaa	CRISPR spacer
caaagttagcgaggtttgacgcatcaaccaaa	Protospacer
********************************

4. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010173 (Escherichia coli strain H8 plasmid A, complete sequence) position: , mismatch: 2, identity: 0.938

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
ttttcggctcggcgcaatatcccggcgcacgc	Protospacer
**.***** ***********************

5. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021729 (Escherichia coli strain Combat11I9 plasmid pCombat11I9-3, complete sequence) position: , mismatch: 2, identity: 0.938

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
ttttcggctcggcgcaatatcccggcgcacgc	Protospacer
**.***** ***********************

6. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046005 (Escherichia coli strain 1919D3 plasmid p1919D3-2, complete sequence) position: , mismatch: 2, identity: 0.938

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
ttttcggctcggcgcaatatcccggcgcacgc	Protospacer
**.***** ***********************

7. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MG592476 (Vibrio phage 1.104.O._10N.286.49.A12, partial genome) position: , mismatch: 2, identity: 0.938

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
ttctcggctcggcgcaatatccctgcgcacgc	Protospacer
******** ************** ********

8. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MG592538 (Vibrio phage 1.171.O._10N.261.52.F12, partial genome) position: , mismatch: 2, identity: 0.938

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
ttctcggctcggcgcagtatcccggcgcacgc	Protospacer
******** *******.***************

9. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MG592428 (Vibrio phage 1.046.O._10N.286.52.E3, partial genome) position: , mismatch: 2, identity: 0.938

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
ttctcggctcggcgcaatatccctgcgcacgc	Protospacer
******** ************** ********

10. spacer 1.22|2932951|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP041251 (Raoultella electrica strain DSM 102253 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.875

tacagtaaaccaatgccatgccaacatcgctc	CRISPR spacer
tacagtaaaccaatgccatacctacatcaccc	Protospacer
*******************.** *****.*.*

11. spacer 1.24|2933073|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NC_011148 (Salmonella enterica subsp. enterica serovar Agona str. SL483 plasmid, complete sequence) position: , mismatch: 4, identity: 0.875

caaagttagcgaggtttgacgcatcaaccaaa	CRISPR spacer
caaagttagcgaggtttgaagcatcaatcagg	Protospacer
******************* *******.**..

12. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to CP054337 (Escherichia coli strain SCU-120 plasmid pSCU-120-2, complete sequence) position: , mismatch: 4, identity: 0.875

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
gcctctgctcggcgcaatatcccggcgcacgc	Protospacer
 .*** ** ***********************

13. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021537 (Escherichia coli strain AR_0119 plasmid unitig_3, complete sequence) position: , mismatch: 4, identity: 0.875

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
gcctctgctcggcgcaatatcccggcgcacgc	Protospacer
 .*** ** ***********************

14. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026938 (Escherichia coli strain CFS3292 plasmid pCFS3292-3, complete sequence) position: , mismatch: 4, identity: 0.875

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
gcctctgctcggcgcaatatcccggcgcacgc	Protospacer
 .*** ** ***********************

15. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH844525 (Escherichia coli strain SCEC128 plasmid pSCEC128, complete sequence) position: , mismatch: 4, identity: 0.875

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
gcctctgctcggcgcaatatcccggcgcacgc	Protospacer
 .*** ** ***********************

16. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH580301 (Escherichia coli strain 1107 plasmid p1107-99K, complete sequence) position: , mismatch: 4, identity: 0.875

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
gcctctgctcggcgcaatatcccggcgcacgc	Protospacer
 .*** ** ***********************

17. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042508 (Leclercia adecarboxylata strain E1 plasmid pE1_003, complete sequence) position: , mismatch: 4, identity: 0.875

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
ttgactgcgcggcgtaatatcccggcgcacgc	Protospacer
**  * ********.*****************

18. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040893 (Leclercia adecarboxylata strain Z96-1 plasmid pZ96-1_2, complete sequence) position: , mismatch: 4, identity: 0.875

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
ttgactgcgcggcgtaatatcccggcgcacgc	Protospacer
**  * ********.*****************

19. spacer 1.2|2931728|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022304 (Thalassococcus sp. S3 plasmid pS3A, complete sequence) position: , mismatch: 5, identity: 0.844

atggat-ggctcatatccggtttctgtttctgc	CRISPR spacer
-tggatcagctcatagccggtttctgtctcttc	Protospacer
 ***** .******* ***********.*** *

20. spacer 1.18|2932707|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NC_021559 (Prochlorococcus phage P-SSM3 genomic sequence) position: , mismatch: 5, identity: 0.844

actggaggagaatttgatgcaggtga-agcgtc	CRISPR spacer
tctggagcagaatttgctgcaggtgatagtgt-	Protospacer
 ****** ******** ********* **.**

21. spacer 1.2|2931728|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023072 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666a, complete sequence) position: , mismatch: 6, identity: 0.812

atggatggctcatatccggtttctgtttctgc	CRISPR spacer
agggatgcctcatatccggtttctgttcgtca	Protospacer
* ***** *******************. *

22. spacer 1.18|2932707|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MN694803 (Marine virus AFVG_250M814, complete genome) position: , mismatch: 6, identity: 0.812

--actggaggagaatttgatgcaggtgaagcgtc	CRISPR spacer
cgcctgga--agaatatgatgcaggtgaagggtt	Protospacer
   *****  ***** ************** **.

23. spacer 1.24|2933073|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NC_017903 (Escherichia coli Xuzhou21 plasmid pO157_Sal, complete sequence) position: , mismatch: 6, identity: 0.812

caaagttagcgaggtttgacgcatcaaccaaa	CRISPR spacer
caaagttagcgaggttagaagcatcaataagg	Protospacer
**************** ** *******. *..

24. spacer 1.10|2932217|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MH651182 (Gordonia phage Neville, complete genome) position: , mismatch: 7, identity: 0.781

cccgacagttgctcaggtggctgccgccaagg	CRISPR spacer
cttgacagttgctcaggtgactgccgagattg	Protospacer
*..****************.******  *  *

25. spacer 2.2|2949576|32|NC_022525|CRISPRCasFinder,CRT matches to MF495478 (Aeromonas salmonicida plasmid pS121-1b, complete sequence) position: , mismatch: 7, identity: 0.781

gacaacgcatcaagaccgatatacaccacgcc	CRISPR spacer
gtcatggcatccagaccgatatagaccactgc	Protospacer
* **  ***** *********** *****  *

26. spacer 2.2|2949576|32|NC_022525|CRISPRCasFinder,CRT matches to NZ_CP038450 (Aeromonas media strain R50-22 plasmid pAeme6, complete sequence) position: , mismatch: 7, identity: 0.781

gacaacgcatcaagaccgatatacaccacgcc	CRISPR spacer
gtcatggcatccagaccgatatagaccactgc	Protospacer
* **  ***** *********** *****  *

27. spacer 2.2|2949576|32|NC_022525|CRISPRCasFinder,CRT matches to NZ_CP022170 (Aeromonas salmonicida strain S121 plasmid pS121-1a, complete sequence) position: , mismatch: 7, identity: 0.781

gacaacgcatcaagaccgatatacaccacgcc	CRISPR spacer
gtcatggcatccagaccgatatagaccactgc	Protospacer
* **  ***** *********** *****  *

28. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NC_017385 (Ketogulonicigenium vulgare WSH-001 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.781

ttctcggcgcggcgcaatatcccggc-gcacgc	CRISPR spacer
ctggcggcgcggggcaatatcgcggcggcatg-	Protospacer
.*  ******** ******** **** ***.*

29. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012910 (Ketogulonicigenium vulgare strain Hbe602 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.781

ttctcggcgcggcgcaatatcccggc-gcacgc	CRISPR spacer
ctggcggcgcggggcaatatcgcggcggcatg-	Protospacer
.*  ******** ******** **** ***.*

30. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NC_014626 (Ketogulonicigenium vulgare Y25 plasmid pYP12, complete sequence) position: , mismatch: 7, identity: 0.781

ttctcggcgcggcgcaatatcccggc-gcacgc	CRISPR spacer
ctggcggcgcggggcaatatcgcggcggcatg-	Protospacer
.*  ******** ******** **** ***.*

31. spacer 2.12|2950186|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP006990 (Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence) position: , mismatch: 7, identity: 0.781

tagtcga--tcggtctggagcagataaaccggca	CRISPR spacer
--atcggccttggtcaggagcagatagaccggca	Protospacer
  .***.  *.**** **********.*******

32. spacer 2.12|2950186|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013556 (Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence) position: , mismatch: 7, identity: 0.781

tagtcga--tcggtctggagcagataaaccggca	CRISPR spacer
--atcggccttggtcaggagcagatagaccggca	Protospacer
  .***.  *.**** **********.*******

33. spacer 2.12|2950186|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020911 (Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence) position: , mismatch: 7, identity: 0.781

tagtcga--tcggtctggagcagataaaccggca	CRISPR spacer
--atcggccttggtcaggagcagatagaccggca	Protospacer
  .***.  *.**** **********.*******

34. spacer 2.12|2950186|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 7, identity: 0.781

tagtcga--tcggtctggagcagataaaccggca	CRISPR spacer
--atcggccttggtcaggagcagatagaccggca	Protospacer
  .***.  *.**** **********.*******

35. spacer 2.12|2950186|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013567 (Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence) position: , mismatch: 7, identity: 0.781

tagtcga--tcggtctggagcagataaaccggca	CRISPR spacer
--atcggccttggtcaggagcagatagaccggca	Protospacer
  .***.  *.**** **********.*******

36. spacer 2.12|2950186|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021127 (Rhizobium sp. Kim5 plasmid pRetKim5c, complete sequence) position: , mismatch: 7, identity: 0.781

tagtcga--tcggtctggagcagataaaccggca	CRISPR spacer
--atcggccttggtcaggagcagatagaccggca	Protospacer
  .***.  *.**** **********.*******

37. spacer 2.13|2950247|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to KX657793 (Mycobacterium phage DarthPhader, complete genome) position: , mismatch: 7, identity: 0.781

tttgtccagttcggcgatgcggcgttctgcgg	CRISPR spacer
cttgtccagttcggctatgcggcggtcgaacg	Protospacer
.************** ******** ** .  *

38. spacer 2.20|2949521|31|NC_022525|PILER-CR matches to JX434031 (Pseudomonas phage JBD24, complete genome) position: , mismatch: 7, identity: 0.774

taact--catcacatccgcgtcagacctcgtga	CRISPR spacer
--actgccatcacattcgcggcagacctcgccg	Protospacer
  ***  ********.**** *********. .

39. spacer 2.21|2949582|31|NC_022525|PILER-CR matches to MF495478 (Aeromonas salmonicida plasmid pS121-1b, complete sequence) position: , mismatch: 7, identity: 0.774

gacaacgcatcaagaccgatatacaccacgc	CRISPR spacer
gtcatggcatccagaccgatatagaccactg	Protospacer
* **  ***** *********** *****

40. spacer 2.21|2949582|31|NC_022525|PILER-CR matches to NZ_CP022170 (Aeromonas salmonicida strain S121 plasmid pS121-1a, complete sequence) position: , mismatch: 7, identity: 0.774

gacaacgcatcaagaccgatatacaccacgc	CRISPR spacer
gtcatggcatccagaccgatatagaccactg	Protospacer
* **  ***** *********** *****

41. spacer 2.21|2949582|31|NC_022525|PILER-CR matches to NZ_CP038450 (Aeromonas media strain R50-22 plasmid pAeme6, complete sequence) position: , mismatch: 7, identity: 0.774

gacaacgcatcaagaccgatatacaccacgc	CRISPR spacer
gtcatggcatccagaccgatatagaccactg	Protospacer
* **  ***** *********** *****

42. spacer 1.11|2932278|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 8, identity: 0.75

gacgacaaaattaatattgttggctggcgtgt	CRISPR spacer
aacgacaaaattaatattgatggcccattttt	Protospacer
.****************** ****. .. * *

43. spacer 1.13|2932400|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049029 (Fluviibacterium aquatile strain SC52 plasmid pSC52_1, complete sequence) position: , mismatch: 8, identity: 0.75

----ttcagagaattgccgccaatagaacagcgcaa	CRISPR spacer
gcgcttc----aatcgccgccaattgaacagcgcgg	Protospacer
    ***    ***.********* *********..

44. spacer 1.23|2933012|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024786 (Nostoc flagelliforme CCNUN1 plasmid pNFSY01, complete sequence) position: , mismatch: 8, identity: 0.75

tgctacaaatggcactccatttattattccgc	CRISPR spacer
tagaagaaaaggcactgcatttattattcaac	Protospacer
*.  * *** ****** ************ .*

45. spacer 1.23|2933012|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026687 (Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM5, complete sequence) position: , mismatch: 8, identity: 0.75

tgctacaaatggcactccatttattattccgc	CRISPR spacer
tagaagaaaaggcactgcatttattattcaac	Protospacer
*.  * *** ****** ************ .*

46. spacer 2.1|2949515|32|NC_022525|CRISPRCasFinder,CRT matches to JX434031 (Pseudomonas phage JBD24, complete genome) position: , mismatch: 8, identity: 0.75

taact--catcacatccgcgtcagacctcgtgac	CRISPR spacer
--actgccatcacattcgcggcagacctcgccga	Protospacer
  ***  ********.**** *********. .

47. spacer 2.2|2949576|32|NC_022525|CRISPRCasFinder,CRT matches to NZ_CP048109 (Klebsiella michiganensis strain BD177 plasmid unnamed1) position: , mismatch: 8, identity: 0.75

gacaacgcatcaagaccgatatacaccacgcc	CRISPR spacer
ctgagtgcatcgaggccgatatacaccacggc	Protospacer
   *..*****.**.*************** *

48. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to NZ_HG938354 (Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence) position: , mismatch: 8, identity: 0.75

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
agggaaaaccgtgacacctgtaaatacgacac	Protospacer
  *** *** *************** * .*.*

49. spacer 2.4|2949698|32|NC_022525|CRISPRCasFinder,CRT matches to NZ_CP017759 (Cupriavidus necator strain NH9 plasmid pENH92, complete sequence) position: , mismatch: 8, identity: 0.75

agcaaactcagtggcagcggcggtgcagtttt	CRISPR spacer
accaaaatcagtggcagcggctgtgctacatc	Protospacer
* **** ************** **** .. *.

50. spacer 2.5|2949759|32|NC_022525|CRISPRCasFinder,CRT matches to NZ_CP017759 (Cupriavidus necator strain NH9 plasmid pENH92, complete sequence) position: , mismatch: 8, identity: 0.75

agcaaactcagtggcagcggcggtgcagtttt	CRISPR spacer
accaaaatcagtggcagcggctgtgctacatc	Protospacer
* **** ************** **** .. *.

51. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448563 (Streptococcus satellite phage Javan601, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

52. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448565 (Streptococcus satellite phage Javan603, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

53. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448571 (Streptococcus satellite phage Javan609, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

54. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448575 (Streptococcus satellite phage Javan612, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

55. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448567 (Streptococcus satellite phage Javan605, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

56. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448574 (Streptococcus satellite phage Javan611, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

57. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448578 (Streptococcus satellite phage Javan615, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

58. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448577 (Streptococcus satellite phage Javan614, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

59. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448573 (Streptococcus satellite phage Javan610, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

60. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448568 (Streptococcus satellite phage Javan606, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

61. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448570 (Streptococcus satellite phage Javan608, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

62. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448564 (Streptococcus satellite phage Javan602, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

63. spacer 2.6|2949820|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MK448566 (Streptococcus satellite phage Javan604, complete genome) position: , mismatch: 8, identity: 0.75

tctaccctatctaacccattagaataaaagga	CRISPR spacer
gcaaccctatctaactcgttagaataaatttc	Protospacer
 * ************.*.**********

64. spacer 2.14|2950308|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MN693945 (Marine virus AFVG_250M952, complete genome) position: , mismatch: 8, identity: 0.75

---gctcggggaagtatcaaccagcagataacggt	CRISPR spacer
tttgctt---taagtataaaccagccgataacggc	Protospacer
   ***.    ****** ******* ********.

65. spacer 2.14|2950308|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MT773554 (Myoviridae sp. isolate BML_2 genomic sequence) position: , mismatch: 8, identity: 0.75

gctcggggaagtatcaaccagcagataacggt	CRISPR spacer
attatggaaactatcaaccagcagataatgtt	Protospacer
..*  **.** *****************.* *

66. spacer 2.21|2949582|31|NC_022525|PILER-CR matches to NZ_CP048109 (Klebsiella michiganensis strain BD177 plasmid unnamed1) position: , mismatch: 8, identity: 0.742

gacaacgcatcaagaccgatatacaccacgc	CRISPR spacer
ctgagtgcatcgaggccgatatacaccacgg	Protospacer
   *..*****.**.***************

67. spacer 1.2|2931728|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049157 (Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence) position: , mismatch: 9, identity: 0.719

atggatggctcatatccggtttctgtttctgc	CRISPR spacer
tcggctggctcatttccggtttctgggtgacc	Protospacer
 .** ******** ***********  *   *

68. spacer 1.2|2931728|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049317 (Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence) position: , mismatch: 9, identity: 0.719

atggatggctcatatccggtttctgtttctgc	CRISPR spacer
tcggctggctcatttccggtttctgggtgacc	Protospacer
 .** ******** ***********  *   *

69. spacer 1.11|2932278|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017833 (Butyrivibrio hungatei strain MB2003 plasmid pNP6, complete sequence) position: , mismatch: 9, identity: 0.719

gacgacaaaattaatattgttggctggcgtgt	CRISPR spacer
cctgacaaaattaatgtttttggctgtcaggc	Protospacer
  .************.** ******* *. *.

70. spacer 1.15|2932522|33|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NC_014825 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL02, complete sequence) position: , mismatch: 9, identity: 0.727

gctgtcgtatatccgttacgcaacccgcgtgcg	CRISPR spacer
gtggtcgtatatcctttacgcaaaccgctgaac	Protospacer
*. *********** ******** ****  .

71. spacer 1.18|2932707|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MN693670 (Marine virus AFVG_250M508, complete genome) position: , mismatch: 9, identity: 0.719

actggaggagaatttgatgcaggtgaagcgtc	CRISPR spacer
agattagaagaatttgacgcaggtgaaggcta	Protospacer
*    **.*********.**********  *

72. spacer 1.18|2932707|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MN693662 (Marine virus AFVG_250M383, complete genome) position: , mismatch: 9, identity: 0.719

actggaggagaatttgatgcaggtgaagcgtc	CRISPR spacer
agattagaagaatttgacgcaggtgaaggcta	Protospacer
*    **.*********.**********  *

73. spacer 1.18|2932707|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MN694314 (Marine virus AFVG_250M513, complete genome) position: , mismatch: 9, identity: 0.719

actggaggagaatttgatgcaggtgaagcgtc	CRISPR spacer
agattagaagaatttgacgcaggtgaaggcta	Protospacer
*    **.*********.**********  *

74. spacer 1.23|2933012|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054718 (Salmonella enterica strain 85-0120 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

tgctacaaatggcactccatttattattccgc	CRISPR spacer
cgccccacatggcattccatttattattagcg	Protospacer
.**. ** ******.*************

75. spacer 1.23|2933012|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054718 (Salmonella enterica strain 85-0120 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

tgctacaaatggcactccatttattattccgc	CRISPR spacer
cgccccacatggcattccatttattattagcg	Protospacer
.**. ** ******.*************

76. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
gcgttcacgctgcgcaatatcccggcgcgcga	Protospacer
 . *. .*** *****************.**

77. spacer 2.9|2950003|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MN694334 (Marine virus AFVG_250M1054, complete genome) position: , mismatch: 9, identity: 0.719

agtgccatcatcccactcgcaaagattcagca	CRISPR spacer
ggtgccatcagccaactcgcaaagccgaacct	Protospacer
.********* ** ********** .  * *

78. spacer 2.13|2950247|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.719

tttgtccagttcggcgatgcggcgttctgcgg	CRISPR spacer
ggaatgaggtccggcaatgcggcgttctgcgg	Protospacer
   .*  .**.****.****************

79. spacer 1.18|2932707|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MN694051 (Marine virus AFVG_250M33, complete genome) position: , mismatch: 10, identity: 0.688

actggaggagaatttgatgcaggtgaagcgtc	CRISPR spacer
cgcttagaagaatttgatgctggtgaaggcta	Protospacer
  .  **.************ *******  *

80. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349325 (Cyanophage S-RIM12 isolate W1_24_0910, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

81. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349322 (Cyanophage S-RIM12 isolate Sn_31_0910, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

82. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349320 (Cyanophage S-RIM12 isolate RW_29_1109, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

83. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349310 (Cyanophage S-RIM12 isolate RW_01_0310, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

84. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349321 (Cyanophage S-RIM12 isolate Sn_07_0910, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

85. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349324 (Cyanophage S-RIM12 isolate W1_12_0610, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

86. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349314 (Cyanophage S-RIM12 isolate RW_07_1112, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

87. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349316 (Cyanophage S-RIM12 isolate RW_22_0110, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

88. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KJ019063 (Synechococcus phage ACG-2014c isolate Syn7803C97, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttctg	Protospacer
  .  ** ********** ********* *

89. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KJ019027 (Synechococcus phage ACG-2014c isolate Syn7803C43, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttctg	Protospacer
  .  ** ********** ********* *

90. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349315 (Cyanophage S-RIM12 isolate RW_14_0101, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

91. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349317 (Cyanophage S-RIM12 isolate RW_25_0210, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

92. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to NC_019444 (Synechococcus phage S-MbCM6, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttctg	Protospacer
  .  ** ********** ********* *

93. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KJ019128 (Synechococcus phage ACG-2014c isolate Syn7803US88, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

94. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to NC_015285 (Prochlorococcus phage Syn33, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

95. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349309 (Cyanophage S-RIM12 isolate Np_22_1112, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

96. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349319 (Cyanophage S-RIM12 isolate RW_28_1109, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

97. spacer 2.3|2949637|32|NC_022525|CRISPRCasFinder,CRT matches to KX349318 (Cyanophage S-RIM12 isolate RW_27_0310, complete genome) position: , mismatch: 10, identity: 0.688

ccggacaacagtgacacctgtaaattctgcgc	CRISPR spacer
aaactcaccagtgacaccagtaaattcttcag	Protospacer
  .  ** ********** ********* *.

98. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010682 (Phaeobacter piscinae strain P14 plasmid pP14_a, complete sequence) position: , mismatch: 10, identity: 0.688

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
cggcatgcgcggcgcaatatcctggggcaccg	Protospacer
.  .  ****************.** ****

99. spacer 2.7|2949881|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010644 (Phaeobacter piscinae strain P36 plasmid pP36_a, complete sequence) position: , mismatch: 10, identity: 0.688

ttctcggcgcggcgcaatatcccggcgcacgc	CRISPR spacer
cggcgtgcgcggcgcaatatcctggggcaccg	Protospacer
.  .  ****************.** ****

100. spacer 2.13|2950247|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KU140623 (Sinorhizobium sp. M14 plasmid pSinB, complete sequence) position: , mismatch: 10, identity: 0.688

tttgtccagttcggcgatgcggcgttctgcgg	CRISPR spacer
cgcttccagttcggcgatgcgctgttcgatcg	Protospacer
. . ***************** .**** .. *

101. spacer 2.15|2950369|32|NC_022525|CRISPRCasFinder,CRT,PILER-CR matches to MN694012 (Marine virus AFVG_250M887, complete genome) position: , mismatch: 10, identity: 0.688

tgcgaaatagtcacgtgagcaacgccgacaag	CRISPR spacer
ggcgtaatagttacgtgagcaacgtaagtacc	Protospacer
 *** ******.************. ...*

102. spacer 1.1|2931667|32|NC_022525|CRISPRCasFinder,CRT matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.656

ttttcagcccttgccgactgcggaacgcccct	CRISPR spacer
cgccgcacccttgccgactgcgggatgcccga	Protospacer
. ..  .****************.*.****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1039450 : 1141329

102

Salmonella_phage(44.64%)

protease,holin,head,terminase,tRNA,capsid,lysis,tail,portal

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001154028.1\|1039450_1040254_+\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA
WP_001288828.1\|1040246_1041569_+	chromosome partition protein MukF	NA	NA	NA	NA
WP_000060025.1\|1041549_1042254_+	chromosome partition protein MukE	NA	NA	NA	NA
WP_017465607.1\|1042253_1046720_+	chromosome partition protein MukB	NA	NA	NA	NA
WP_017465608.1\|1047064_1048912_+	L,D-transpeptidase	NA	NA	NA	NA
WP_000357052.1\|1049169_1049718_+	YcbK family protein	A0A0K1LKR7	Rhodobacter_phage	1.2e-05	33.7
WP_001109471.1\|1049745_1050393_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_000462653.1\|1050454_1051645_-	aspartate transaminase	NA	NA	NA	NA
WP_000977709.1\|1051829_1052921_-	porin OmpF	Q1MVN1	Enterobacteria_phage	1.7e-99	51.7
WP_000117867.1\|1053526_1054927_-\|tRNA	asparagine--tRNA ligase	A0A2K9V902	Bandra_megavirus	4.5e-81	35.8
WP_000762342.1\|1055127_1055589_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_021294193.1\|1055905_1057120_+	diaminopropionate ammonia-lyase	NA	NA	NA	NA
WP_017465610.1\|1057365_1058799_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_017465611.1\|1058879_1060082_-	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
WP_001262307.1\|1060276_1061569_-	DUF3596 domain-containing protein	S4TSP2	Salmonella_phage	3.4e-253	100.0
WP_000065276.1\|1061613_1061862_-	excisionase family protein	S4TND0	Salmonella_phage	4.7e-42	100.0
WP_001237031.1\|1061902_1062142_-	DUF4060 family protein	S4TR31	Salmonella_phage	2.0e-37	100.0
WP_010835407.1\|1062184_1063342_-	recombinase RecT	S4TTE8	Salmonella_phage	7.9e-217	99.7
WP_001750117.1\|1063304_1066232_-	PD-(D/E)XK nuclease-like domain-containing protein	S4TNL0	Salmonella_phage	0.0e+00	99.8
WP_001750116.1\|1066358_1066709_-	hypothetical protein	S4TSN6	Salmonella_phage	3.2e-60	96.6
WP_000551857.1\|1066730_1066901_-	hypothetical protein	K7PGY4	Enterobacteria_phage	9.7e-07	49.0
WP_001750115.1\|1067297_1067504_+	hypothetical protein	K7P7I0	Enterobacteria_phage	4.3e-17	69.1
WP_001750114.1\|1067530_1068472_-	hypothetical protein	NA	NA	NA	NA
WP_001230956.1\|1068577_1068973_-	helix-turn-helix domain-containing protein	K7PM35	Enterobacteria_phage	3.5e-47	72.5
WP_000992434.1\|1069077_1069314_+	helix-turn-helix domain-containing protein	A0A0M4QX15	Salmonella_phage	9.0e-27	73.1
WP_010835408.1\|1069279_1069654_+	hypothetical protein	S4TTD7	Salmonella_phage	1.9e-63	98.4
WP_001540689.1\|1069738_1070722_+	replication protein	H6WRX7	Salmonella_phage	1.9e-163	100.0
WP_001750113.1\|1070724_1071474_+	ATP-binding protein	H6WRX8	Salmonella_phage	7.3e-139	99.2
WP_000113626.1\|1071484_1071832_+	DUF977 family protein	H6WRX9	Salmonella_phage	4.5e-59	100.0
WP_000065089.1\|1071828_1072149_+	hypothetical protein	H6WRY0	Salmonella_phage	6.7e-25	65.5
WP_000974174.1\|1072148_1072394_+	hypothetical protein	Q5G8U9	Enterobacteria_phage	3.0e-33	88.9
WP_000132543.1\|1072704_1073922_+	hypothetical protein	J9Q803	Salmonella_phage	3.1e-118	53.3
WP_107251218.1\|1073902_1073971_+	DUF551 domain-containing protein	NA	NA	NA	NA
WP_000802853.1\|1074064_1074391_+	hypothetical protein	NA	NA	NA	NA
WP_001217669.1\|1074638_1074872_+	DinI family protein	H6WRY5	Salmonella_phage	5.6e-37	100.0
WP_014343878.1\|1074988_1075237_+	hypothetical protein	A0A0U2C0C8	Salmonella_phage	1.6e-42	100.0
WP_001750112.1\|1075271_1075874_+	DUF1367 family protein	S4TTI0	Salmonella_phage	2.8e-109	99.0
WP_001096547.1\|1076082_1076694_+	recombination protein NinG	A0A0M4RU10	Salmonella_phage	4.2e-92	99.5
WP_001617856.1\|1076690_1076837_+	YlcG family protein	A0A0M5M7B2	Salmonella_phage	4.3e-19	97.9
WP_001047630.1\|1076826_1077624_+	antitermination protein	A0A0M4S661	Salmonella_phage	4.0e-151	99.6
WP_001534733.1\|1078022_1078148_+	hypothetical protein	NA	NA	NA	NA
WP_000798705.1\|1078283_1078733_-	hypothetical protein	NA	NA	NA	NA
WP_001574216.1\|1080055_1080385_+\|holin	phage holin, lambda family	A0A0M3ULK9	Salmonella_phage	5.8e-56	100.0
WP_000984583.1\|1080368_1080821_+	lysozyme	A0A0M4R365	Salmonella_phage	4.6e-80	98.7
WP_031607240.1\|1080838_1081288_+\|lysis	lysis protein	A0A0M4RD57	Salmonella_phage	6.1e-64	90.4
WP_001252721.1\|1081616_1082120_+	hypothetical protein	NA	NA	NA	NA
WP_001750111.1\|1082376_1082778_-	PPC domain-containing protein	NA	NA	NA	NA
WP_001102153.1\|1083063_1083609_+\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	1.5e-56	80.6
WP_000623092.1\|1083580_1085512_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	1.3e-259	65.9
WP_000201415.1\|1085495_1085699_+	gpW family protein	K7PM10	Enterobacteria_phage	1.9e-17	73.8
WP_000831821.1\|1085695_1087276_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	9.6e-189	62.8
WP_001189498.1\|1087265_1088762_+	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	1.1e-96	52.2
WP_000011260.1\|1088774_1089122_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	9.2e-20	52.7
WP_000522566.1\|1089176_1090205_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.7e-114	61.1
WP_000201485.1\|1090262_1090628_+	DNA-packaging protein FI	NA	NA	NA	NA
WP_000083293.1\|1090638_1091016_+\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	1.5e-28	55.6
WP_000677089.1\|1091002_1091581_+\|tail	phage tail protein	A5LH33	Enterobacteria_phage	3.7e-82	80.2
WP_000033885.1\|1091577_1091979_+\|tail	tail protein	Q9G0F3	Phage_Gifsy-1	8.1e-52	100.0
WP_000971953.1\|1091986_1092733_+	Ig-like domain-containing protein	A0A291AWU6	Escherichia_phage	1.9e-99	76.9
WP_000479607.1\|1092783_1093179_+\|tail	phage minor tail protein G	A5LH36	Enterobacteria_phage	2.3e-30	56.5
WP_010989052.1\|1093175_1093514_+\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	1.3e-31	62.4
WP_000372075.1\|1093485_1096581_+\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	4.8e-277	61.7
WP_000447370.1\|1096583_1096913_+\|tail	phage tail protein	A5LH39	Enterobacteria_phage	7.3e-43	71.3
WP_001152686.1\|1096922_1097621_+\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	1.6e-103	75.9
WP_000662738.1\|1097627_1098365_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	9.8e-128	84.2
WP_001750110.1\|1098262_1098910_+\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	1.6e-89	78.1
WP_000514902.1\|1098971_1102334_+	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	79.5
WP_000178849.1\|1102372_1102615_+	hypothetical protein	NA	NA	NA	NA
WP_023193196.1\|1102668_1105164_+\|tail	prophage tail fiber N-terminal domain-containing protein	E5G6P0	Salmonella_phage	7.3e-159	76.1
WP_000143168.1\|1105163_1105745_+\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	3.3e-94	88.9
WP_010835411.1\|1106574_1108065_-	type III secretion effector GogB	Q9MBM1	Phage_Gifsy-1	1.6e-254	98.6
WP_001536069.1\|1108632_1109433_-	hypothetical protein	NA	NA	NA	NA
WP_000497440.1\|1109908_1110115_-	DinI-like family protein	S4TNM0	Salmonella_phage	1.8e-31	100.0
WP_000193775.1\|1110541_1113154_+	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	3.7e-20	22.8
WP_000291723.1\|1113361_1114372_+	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_001220671.1\|1114537_1115080_+	cell division protein ZapC	NA	NA	NA	NA
WP_000224072.1\|1115076_1116186_-	YcbX family protein	NA	NA	NA	NA
WP_001086485.1\|1116284_1118393_+	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_000053044.1\|1118405_1120313_+	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	2.4e-53	29.8
WP_017465789.1\|1120327_1121581_+	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_017465790.1\|1121585_1123226_+	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_000759136.1\|1123222_1123786_+	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_001537784.1\|1124041_1124209_+	ribosome modulation factor	NA	NA	NA	NA
WP_000227928.1\|1124308_1124827_-	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_017465791.1\|1124895_1126656_-\|protease	Lon protease family protein	NA	NA	NA	NA
WP_017465792.1\|1126841_1127294_+	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_001674965.1\|1127365_1128418_-	porin OmpA	NA	NA	NA	NA
WP_017465793.1\|1128775_1129285_-	cell division inhibitor SulA	NA	NA	NA	NA
WP_001202375.1\|1129501_1130107_+	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_000950861.1\|1130093_1132247_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_001261222.1\|1132265_1132712_-	YccF domain-containing protein	NA	NA	NA	NA
WP_017465794.1\|1132835_1134890_+	DNA helicase IV	A7KV33	Bacillus_phage	8.5e-20	27.6
WP_000424187.1\|1134925_1135384_-	methylglyoxal synthase	NA	NA	NA	NA
WP_000847719.1\|1135478_1136141_-	DUF2057 family protein	NA	NA	NA	NA
WP_001537782.1\|1136314_1136728_+	CoA-binding protein	NA	NA	NA	NA
WP_000561983.1\|1136772_1137090_-	heat shock protein HspQ	NA	NA	NA	NA
WP_000140480.1\|1137147_1138359_-	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_000859416.1\|1138573_1139122_+	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_017465795.1\|1139147_1139927_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_000072884.1\|1139975_1140257_+	acylphosphatase	NA	NA	NA	NA
WP_000904446.1\|1140253_1140583_-	sulfurtransferase TusE	NA	NA	NA	NA
WP_000374046.1\|1140669_1141329_-\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	2.7e-44	52.4

DBSCAN-SWA_2

2038579 : 2045847

Morganella_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001157305.1\|2038579_2040010_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	1.0e-104	57.4
WP_000377042.1\|2040083_2040779_-	phosphohydrolase	A0A1D6Y7U0	Golden_Marseillevirus	2.8e-07	27.1
WP_017465543.1\|2040858_2041170_-	hypothetical protein	NA	NA	NA	NA
WP_017465542.1\|2041819_2043031_+	porin OmpC	Q1MVN1	Enterobacteria_phage	4.4e-109	56.2
WP_024131163.1\|2043290_2043479_-	hypothetical protein	NA	NA	NA	NA
WP_000208509.1\|2043489_2043702_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	3.9e-21	70.0
WP_017465541.1\|2044156_2045425_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	3.5e-226	91.7
WP_000394197.1\|2045427_2045847_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.5e-36	60.5

DBSCAN-SWA_3

2219653 : 2228824

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000195330.1\|2219653_2221687_+\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	1.0e-54	27.6
WP_000703143.1\|2221927_2222386_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	2.4e-52	71.9
WP_017465874.1\|2222557_2223088_+	YehR family lipoprotein	NA	NA	NA	NA
WP_000950413.1\|2223144_2223612_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	3.9e-74	90.3
WP_000598637.1\|2223658_2224378_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_000272850.1\|2224374_2226060_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	4.8e-279	91.3
WP_001240418.1\|2226282_2227014_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	4.5e-101	87.9
WP_001261696.1\|2227073_2227181_+	protein YohO	NA	NA	NA	NA
WP_000824854.1\|2227161_2227893_-	ABC transporter permease	NA	NA	NA	NA
WP_000569168.1\|2227876_2228824_-	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	2.8e-10	27.8

DBSCAN-SWA_4

4269902 : 4316975

Burkholderia_phage(36.36%)

tail,holin,tRNA,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022544687.1\|4269902_4270631_-	hypothetical protein	A0A077SLK3	Escherichia_phage	7.3e-35	37.3
WP_017465885.1\|4271369_4271825_-	hypothetical protein	NA	NA	NA	NA
WP_017465886.1\|4271821_4272427_-	DUF4376 domain-containing protein	NA	NA	NA	NA
WP_017465887.1\|4272431_4274201_-\|tail	tail fiber protein	A0A0M3ULH6	Salmonella_phage	3.2e-52	40.5
WP_000359504.1\|4274203_4274836_-\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	1.1e-23	56.4
WP_000951730.1\|4274828_4275944_-\|plate	baseplate J/gp47 family protein	Q6QI99	Burkholderia_phage	3.1e-101	52.2
WP_001093501.1\|4275934_4276294_-	GPW/gp25 family protein	Q6QIA0	Burkholderia_phage	2.8e-35	64.2
WP_001095011.1\|4276457_4278005_-	membrane protein	B9UDL6	Salmonella_phage	1.9e-48	29.9
WP_000703628.1\|4278004_4278934_-	glycosyltransferase family 2 protein	S5FKN0	Shigella_phage	7.9e-151	84.1
WP_000593184.1\|4278930_4279293_-	GtrA family protein	U5P0S6	Shigella_phage	9.6e-44	70.8
WP_017465888.1\|4279620_4280343_-\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	3.9e-12	42.0
WP_017465889.1\|4280352_4281396_-	phage late control D family protein	A4JWL3	Burkholderia_virus	6.5e-77	45.9
WP_017465890.1\|4281383_4281593_-\|tail	tail protein X	A4JWL2	Burkholderia_virus	2.8e-16	58.8
WP_017465891.1\|4281592_4282546_-\|tail	phage tail protein	A4JWL1	Burkholderia_virus	2.3e-36	50.8
WP_001262486.1\|4282545_4284900_-\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	4.0e-66	30.9
WP_001185654.1\|4284996_4285125_-\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_001003639.1\|4285084_4285402_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_000907494.1\|4285453_4285978_-\|tail	phage major tail tube protein	Q6QIA9	Burkholderia_phage	2.8e-68	69.5
WP_000729852.1\|4285977_4287405_-\|tail	phage tail sheath family protein	A4JWK5	Burkholderia_virus	1.1e-194	70.9
WP_000875314.1\|4287394_4287592_-	hypothetical protein	Q6QIB1	Burkholderia_phage	8.6e-07	52.9
WP_000449433.1\|4287588_4288044_-	Gp37 family protein	NA	NA	NA	NA
WP_017465892.1\|4288204_4288519_-	hypothetical protein	Q6QIC4	Burkholderia_phage	1.1e-19	48.2
WP_017465893.1\|4288531_4289137_-	lytic transglycosylase domain-containing protein	Q5ZQZ1	Pseudomonas_phage	4.2e-60	59.9
WP_001226439.1\|4289139_4289427_-\|holin	putative holin	Q6QIC8	Burkholderia_phage	3.0e-16	48.1
WP_000615248.1\|4290003_4290351_+	DNA-binding protein	Q6QIE8	Burkholderia_phage	4.9e-21	51.5
WP_000136394.1\|4290481_4291831_-	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
WP_000790028.1\|4292175_4293825_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_001541297.1\|4294268_4294511_+	outer membrane protein	NA	NA	NA	NA
WP_126489750.1\|4294544_4295213_+	YjbF family lipoprotein	NA	NA	NA	NA
WP_000977968.1\|4295209_4295947_+	capsule biosynthesis GfcC family protein	NA	NA	NA	NA
WP_000750810.1\|4295946_4298043_+	YjbH domain-containing protein	NA	NA	NA	NA
WP_000982749.1\|4298185_4298596_+	phosphate-starvation-inducible protein PsiE	NA	NA	NA	NA
WP_001252081.1\|4298761_4299652_-	maltose ABC transporter permease MalG	NA	NA	NA	NA
WP_000382570.1\|4299666_4301211_-	maltose ABC transporter permease MalF	NA	NA	NA	NA
WP_000695415.1\|4301342_4302533_-	maltose/maltodextrin ABC transporter substrate-binding protein MalE	NA	NA	NA	NA
WP_000179176.1\|4302894_4304004_+	maltose/maltodextrin ABC transporter ATP-binding protein MalK	Q6GZ03	Mycoplasma_phage	6.2e-17	47.2
WP_017465895.1\|4304092_4305451_+	maltoporin	NA	NA	NA	NA
WP_017465896.1\|4305614_4306532_+	maltose operon protein MalM	NA	NA	NA	NA
WP_000019230.1\|4306713_4307211_+	chorismate lyase	NA	NA	NA	NA
WP_000455249.1\|4307224_4308097_+	4-hydroxybenzoate octaprenyltransferase	NA	NA	NA	NA
WP_000017360.1\|4308195_4310616_-	glycerol-3-phosphate 1-O-acyltransferase PlsB	NA	NA	NA	NA
WP_000002900.1\|4310786_4311155_+	diacylglycerol kinase	NA	NA	NA	NA
WP_000646079.1\|4311263_4311872_+	repressor LexA	Q9G0C2	Lactococcus_phage	1.0e-13	38.0
WP_001128112.1\|4312050_4313376_+	MATE family efflux transporter DinF	NA	NA	NA	NA
WP_001575282.1\|4313372_4313486_+	hypothetical protein	NA	NA	NA	NA
WP_001030592.1\|4313507_4313717_+	CsbD family protein	NA	NA	NA	NA
WP_000416271.1\|4313816_4314332_-	zinc uptake transcriptional repressor Zur	NA	NA	NA	NA
WP_001039337.1\|4314578_4315889_+	conjugal transfer protein TraF	NA	NA	NA	NA
WP_017465897.1\|4315976_4316975_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022525

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection