CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022576	Candidatus Symbiobacter mobilis CR, complete sequence	5 crisprs	cas6,cas10,csm3gr7,csm4gr5,csm5gr7,csx1,cmr1gr7,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,cas2,cas1,DEDDh,WYL,c2c9_V-U4,RT,DinG,cas3f,cas6f,cas7f,cas5f,cas8f,PD-DExK	1	30	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_022576_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022576_1

882539-883700

TypeIII

Consensus_repeat	Method
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	PILER-CR
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CRISPRCasFinder
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CRT

16 spacers

cas2,cas1,cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,csx1

The CRISPR arrays of NC_022576_1

>merge|NC_022576|1|882539-883700|PILER-CR,CRISPRCasFinder,CRT
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACCCACTAGTGCGTTCCACCAGTCGAGGCACTCAACGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACTTCCACAACTGCCCAAGCATACGGAACATCGTAGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACTTGCGCGTTGTTACGTGTAACCAATGCCATGATGGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACGTCCCCTCCTTCATCCACGCTACTTACGCGCACAGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACACCCACGCCGCAATCTCATCGTCACTTTTGCTCAGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACTTATTCAGGATCTGTTGATGCATCGCATTACCGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACGACAACGTCATGGCGACGTTTATTGGGGGGTACGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACAAACAATACATTACAGGGACTGACGCCTACCTGGGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACCCTGATCAGGGAAGGACCGTACTGGTACGCTACGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACCTTTGTAGATCAGCGCATTCTTTGCGCCGCTACGGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACAATATAAAGTCTACTTGTAATGCTTAAATCTTGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACCTTCCACAATTGACCAAGCATCCTAAACATAGTAGGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACAGTTTATCTTTACCAAAATGGTTAGCTAAATCAGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACTTATTCAGGACGTGTGCATGGAGCGCATTGCGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACAGAAACTTAATTACAGGGTATTTAATACTCTTAGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACTTTACTCTCCCACCAAGTCTTCTTTCTATATTCGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACC

>NC_022576|1|1|882539-883699|PILER-CR
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCACTAGTGCGTTCCACCAGTCGAGGCACTCAAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTCCACAACTGCCCAAGCATACGGAACATCGTA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTGCGCGTTGTTACGTGTAACCAATGCCATGATG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GTCCCCTCCTTCATCCACGCTACTTACGCGCACA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ACCCACGCCGCAATCTCATCGTCACTTTTGCTCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTATTCAGGATCTGTTGATGCATCGCATTACC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GACAACGTCATGGCGACGTTTATTGGGGGGTAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AAACAATACATTACAGGGACTGACGCCTACCTGG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCTGATCAGGGAAGGACCGTACTGGTACGCTAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CTTTGTAGATCAGCGCATTCTTTGCGCCGCTACG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AATATAAAGTCTACTTGTAATGCTTAAATCTT
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CTTCCACAATTGACCAAGCATCCTAAACATAGTAG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AGTTTATCTTTACCAAAATGGTTAGCTAAATCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTATTCAGGACGTGTGCATGGAGCGCATTGC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AGAAACTTAATTACAGGGTATTTAATACTCTTA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTTACTCTCCCACCAAGTCTTCTTTCTATATTC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC

>NC_022576|1|1|882539-883700|CRISPRCasFinder
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCACTAGTGCGTTCCACCAGTCGAGGCACTCAAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTCCACAACTGCCCAAGCATACGGAACATCGTA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTGCGCGTTGTTACGTGTAACCAATGCCATGATG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GTCCCCTCCTTCATCCACGCTACTTACGCGCACA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ACCCACGCCGCAATCTCATCGTCACTTTTGCTCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTATTCAGGATCTGTTGATGCATCGCATTACC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GACAACGTCATGGCGACGTTTATTGGGGGGTAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AAACAATACATTACAGGGACTGACGCCTACCTGG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCTGATCAGGGAAGGACCGTACTGGTACGCTAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CTTTGTAGATCAGCGCATTCTTTGCGCCGCTACG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AATATAAAGTCTACTTGTAATGCTTAAATCTT
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CTTCCACAATTGACCAAGCATCCTAAACATAGTAG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AGTTTATCTTTACCAAAATGGTTAGCTAAATCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTATTCAGGACGTGTGCATGGAGCGCATTGC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AGAAACTTAATTACAGGGTATTTAATACTCTTA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTTACTCTCCCACCAAGTCTTCTTTCTATATTC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACC

>NC_022576|1|1|882539-883699|CRT
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCACTAGTGCGTTCCACCAGTCGAGGCACTCAAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTCCACAACTGCCCAAGCATACGGAACATCGTA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTGCGCGTTGTTACGTGTAACCAATGCCATGATG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GTCCCCTCCTTCATCCACGCTACTTACGCGCACA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ACCCACGCCGCAATCTCATCGTCACTTTTGCTCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTATTCAGGATCTGTTGATGCATCGCATTACC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GACAACGTCATGGCGACGTTTATTGGGGGGTAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AAACAATACATTACAGGGACTGACGCCTACCTGG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCTGATCAGGGAAGGACCGTACTGGTACGCTAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CTTTGTAGATCAGCGCATTCTTTGCGCCGCTACG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AATATAAAGTCTACTTGTAATGCTTAAATCTT
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CTTCCACAATTGACCAAGCATCCTAAACATAGTAG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AGTTTATCTTTACCAAAATGGTTAGCTAAATCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTATTCAGGACGTGTGCATGGAGCGCATTGC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AGAAACTTAATTACAGGGTATTTAATACTCTTA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTTACTCTCCCACCAAGTCTTCTTTCTATATTC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022576.1\|WP_022771760.1\|893575_893728_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NC_022576.1\|WP_022771747.1\|878947_879232_+\|CRISPR-associated-protein-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_022576.1\|WP_022771745.1\|878040_878316_+\|DUF1778-domain-containing-protein	unknown	unknown	gnl\|CDD\|370057
NC_022576.1\|WP_022771758.1\|891186_891849_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022771752.1\|885784_886927_+\|TIGR02584-family-CRISPR-associated-protein	csx1	pfam09623_csx1_CAS-III	gnl\|CDD\|187872
NC_022576.1\|WP_022771750.1\|880856_882329_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_081699919.1\|883718_884552_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NC_022576.1\|WP_041193235.1\|890049_891132_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022771749.1\|880344_880680_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
NC_022576.1\|WP_022771746.1\|878316_878820_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NC_022576.1\|WP_022771753.1\|887120_888848_+\|exodeoxyribonuclease-VII-large-subunit	unknown	unknown	gnl\|CDD\|234714
NC_022576.1\|WP_041193233.1\|889441_889696_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022771754.1\|888866_889202_+\|exodeoxyribonuclease-VII-small-subunit	unknown	unknown	unknown
NC_022576.1\|WP_187292328.1\|876644_877898_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|224520
NC_022576.1\|WP_022771743.1\|876001_876565_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl\|CDD\|378242
NC_022576.1\|WP_022771759.1\|892042_893251_+\|DUF1887-family-protein	csx1	pfam09002_csx1_CAS-III	gnl\|CDD\|312526
NC_022576.1\|WP_022771748.1\|879298_880270_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_022576.1\|WP_187292329.1\|893243_893390_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022771742.1\|875012_875990_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NC_022576.1\|WP_022771741.1\|873737_874976_+\|hypothetical-protein	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl\|CDD\|187879

Protein	Function_ID	Function_description	E-value
NC_022576.1\|WP_022771747.1\|878947_879232_+\|CRISPR-associated-protein-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.44357e-08
NC_022576.1\|WP_022771745.1\|878040_878316_+\|DUF1778-domain-containing-protein	gnl\|CDD\|370057	pfam08681, DUF1778, Protein of unknown function (DUF1778). This is a family of uncharacterized proteins. The structure of one of the hypothetical proteins in this family has been solved and it forms a helix structure which may form interactions with DNA.	2.64327e-20
NC_022576.1\|WP_022771752.1\|885784_886927_+\|TIGR02584-family-CRISPR-associated-protein	gnl\|CDD\|187872	cd09741, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	2.37732e-81
NC_022576.1\|WP_081699919.1\|883718_884552_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.70965e-21
NC_022576.1\|WP_022771749.1\|880344_880680_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	6.82038e-22
NC_022576.1\|WP_022771746.1\|878316_878820_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.96941e-08
NC_022576.1\|WP_022771753.1\|887120_888848_+\|exodeoxyribonuclease-VII-large-subunit	gnl\|CDD\|234714	PRK00286, xseA, exodeoxyribonuclease VII large subunit; Reviewed.	5.41353e-80
NC_022576.1\|WP_022771759.1\|892042_893251_+\|DUF1887-family-protein	gnl\|CDD\|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	6.12523e-64
NC_022576.1\|WP_187292328.1\|876644_877898_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|224520	COG1604, COG1604, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	9.87745e-20
NC_022576.1\|WP_022771743.1\|876001_876565_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	1.23608e-33
NC_022576.1\|WP_022771760.1\|893575_893728_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	0.00130447
NC_022576.1\|WP_022771748.1\|879298_880270_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.05721e-84
NC_022576.1\|WP_022771742.1\|875012_875990_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	1.96984e-63
NC_022576.1\|WP_022771741.1\|873737_874976_+\|hypothetical-protein	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	1.30008e-53

>NC_022576.1|WP_022771750.1|880856_882329_+|hypothetical-protein
MISITHKIIEDTMNSREIFTLRKQGRSAEALQIAREAYPGNENDLWLLRAYAWSMYDHVKSIIDRCEAKKISPYTIGSRLSPLMREFLHIANPLRSDSVFSHMNRLALKSSRYWPDFLGYARWVGADNFTGEDKKPFVTQEGKIVESFYKRYIRAICRETAAKATDKQTRPQWIEWGSQILKRSLKIEPNDLWFNYYQSKLHLAQGQPDLALQRLIPVLLQHSTAAWPWGLLGDIFETTRPEDTLICYAYATQLARKEIEVAKIRIQLAQRLALVERYNEAANQAWLAIQYRKINGYRIPQGLQNILANNWYHDAVANNTLQPLPPMHSVACKILQELHRQRLTYTRGVIDQNHSTNALTFLATGTESGIGLWNKKFPEIAKLPSGTVIEIGRRETDGPPLDWKISELQEITGLCQAFSGTVIRQADKDFAFVRCELGDVFVPPELAKNFDPVQQYNVKGKAMRKINKQGKSCWSAIHCILQDLYINQAL
>NC_022576.1|WP_022771749.1|880344_880680_+|CRISPR-associated-endonuclease-Cas2
MGTKLKNKYIIAYDICDPKRYNKIHKIIKKYGLPLQYSVYLLDVTRLEIEKLVTELRSLIDPEKDDIRGYYIPQNTWKVSMGTSIVPNDVLPGLWKDQTTAEQDDQYALFT
>NC_022576.1|WP_022771748.1|879298_880270_+|CRISPR-associated-endonuclease-Cas1
MALLVLDRTELDIRVDGDALALYESGTRRGTVPIKLMDRCVIHGARTKLDTGVLQRLAEAGVTTVLISPRAQRRAAIVLGNQHNDAAVRIAQALRVMNQQECWQWSAGIVRAKLARQRKTLSLMQQERPDARKPLFDAIQTIDSIQAHLREFGATTGAVASIRGWEGAAARAYFAALGSVFPPALGFAGRNRRPPKDPVNVCLSLSYTMLHAQAIQQCTITGLDPMLGFYHRPAFGRESLASDLIEPLRPAVDAWVWELLRKRVLREDHFSTNETGCMMGKAGRQIYYTEWEENQKPWQRWLRAQCQNLAKTLRNKGSLCLAE
>NC_022576.1|WP_022771747.1|878947_879232_+|CRISPR-associated-protein-Cas2
MAQRLFHLACYDVAKPRRLKAALKLTRAYATGGQKSVHEIFLTAEERAALLADMALLLDPEEDRFLLLRLDPRSHVYTLGKAMQPADPDYFYVG
>NC_022576.1|WP_022771746.1|878316_878820_+|GNAT-family-N-acetyltransferase
MSGYSIRPLDSEADTARFDCGDAALNDYLRRYATQDVRRNVTRAFIASPLESSTRIAGFFTLSAASIQAETLPENLRKKLPRYPVPVALLGRLAVDREFQGKGLGSILLADVCRKVHAASRTLAVAGIVVDAKSPSASTFYQHFGFLELPGQTSRLILPSSGFADRG
>NC_022576.1|WP_022771745.1|878040_878316_+|DUF1778-domain-containing-protein
MTATVKDTRLHIRCNQQVRHLLDKAAAHSHMSVSEFVLQNAVHHAQAVLAAHETITLSQEDFALFLKALDTPVTPNAALQRAFACHDEQVR
>NC_022576.1|WP_187292328.1|876644_877898_+|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIYQNDVCNPKEKKHFLEKSCPLPPSSVKTVEALIQRQTALVATYGANGLHWHTTSTAPFATGLGNEHPIENGFAFLTPYGLPYLAGSGFKGILRRAAEELALDNDTQNDDGWTWVDIWWLFGFEGAVNKGSQWDSDSDLGHAFERDSYKLAANANLHELLQRLANIDKSMARYADSSDRTAAAQGFLQACLAGSTLRGGLQWRGAVDCWDVYPQPQGNRMVVEIMTPHHGPYYRGDSNPHDSHSPIPVNFLAVPAGSAFHFFAVCHAQKLPQGLQNRWRALLDAAMHHACEWVGFGAKTSVGYGAMQKPAPLPQPAPAKEPRAATTSTEQPIAPVEEGIIWQEATLTYSRNTSEITAGNPPKKTKPLKGDLAKAFLNALPEKQRTRLTKDGAFRNVPVVVKQDGNTWELLRPATTG
>NC_022576.1|WP_022771743.1|876001_876565_+|type-III-B-CRISPR-module-associated-protein-Cmr5
MNQHANQPRAKLTTNKNPQDGNKASTLNPQRTESRTASEPYPGKRRHSTEPSPTGGGQGEGTPQTLDQQRAKLAWGYAQEGIKQYGSDYKNLAKGAPALIMGSGLMPTMAFYEGKKSDPAKALLRHLICGLHERIPTINHQEKDFPSFMKYLQNSLSQDYLRATDEALELLKWIRQFVDALGGDSNA
>NC_022576.1|WP_022771742.1|875012_875990_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MFTATRLAFYAAVSPVHMGAGSAIGAIDSPIQREVHTQHPSFAGSGLKGALRHHFANQWPREGDKPNGLIARIFGPDTNASDYAGALSLTDAQLVALPVRSLRNGFAYVTSPLALARLRRLALQAGVECGWEVPTVPQAGQALLSGAGLADKDQLVLEAFEFRPAKVEPLLANIAQWIAKHALAGAGNQYFQQKFCEDLVLLHDTDFSHFARHGMVVEPHVRINDQTGTADGGGLFYVENLPPESLLVGLVQASDEHRAKPKAGEDGAAALPRLGALDILTAVLNGTTEQPGIHGKVLQIGGDATTGRGLVLVQCAPQEPNQPKA
>NC_022576.1|WP_022771741.1|873737_874976_+|hypothetical-protein
MNAIPVFIQPTDTLFLRGNSAFGGAGEHGVGSLLPQPSVLAGALRSALLAQHPTELARFGAKGCNEDPALQACLGTPQQPGAFSLCAVALAQYHGNAATPMAYLPLPADLVEVDGQLVPLHPQPCPEGICRSGPLPMQAMLRSASQAKPEGGVWLNWAGWLAYLQGQLPTIDQTVKTSHLAKPDPRLGIGMDSTTRTTQQGLIYTTEGFAFRPAELGLASGSGVGGSGKESNGETEPPPAGATGYLAAVEGIGSLLPAQGLLRLGGDGRSARWQRLDVAAWRVPTPPPAKRFRLVLHTPGWFSGGWLPEGVQRNAAGDYILQGKGFSARLVCAAAGRRECISGWDLYEWKPKSAHMVVGAGSVYWFDDFDGDWDKLAEWVEAGLWPQNLSTEQAQRRAEGYNRAWLAAWPQD
>NC_022576.1|WP_081699919.1|883718_884552_-|IS5-family-transposase
MGLIFHDDGWRLHDALWGIIKSSLPEPKKHPLGCHNPRVSDRSAMNAILFVLRTGCQWNALNMTGICSCSSAYRRFREWTKAGVFSALWIQQLVEYDKSQGIDWAWTSMDGALTKAPLAGQQTTGANPTDRGKQGVKRSVLTDGAGIPLAVAIDGANRHDMKLVRSTLEDIKAKRPDPTDTKPQGICLDKGYDFDEVREIVKEFGFTAHIRSRGEEAKSIKQEAGFKARRWVVERTHSWMNRFRRILVRWEKLPETYIAMLHLTCALITLRAYCLLK
>NC_022576.1|WP_022771752.1|885784_886927_+|TIGR02584-family-CRISPR-associated-protein
MNSYDPHQPAGYPRRVLIAVSGLSPQIVTETIYALAADQDEAFVPTEVHLLTTATGAQRAELSLLSEDLGWFHKLQADFHLPGIAFDRSHIHVMRDAQGKPLGDIRTPADNQAAADFITAQVRAFTADDACALHASIAGGRKTMGFYLGYALSLYGRAQDRLSHVLVSEPFESSYDFFYPTPYSRVLRLLNNQLADSVNAQVTLANIPFVSLRHGLPSALLAGTASFNDTVEAAIAALAPPRLRLHLRGQYIVAGTTRIALPPAELALLAVFARRAEMGKEPLPAPAKGVPDKDWATIYLREYRRITGNDAENQDPTHRALRKGMDGEYFSIHKSRLHKTLKNTLGPSANAYLIADGGTRPRLYQLALNADAIAFEETVV
>NC_022576.1|WP_022771753.1|887120_888848_+|exodeoxyribonuclease-VII-large-subunit
MANTYLIVTYSEKDAAKALGAKWDSVQRSWYVPEGRELAPFSQWLPKDGVATKATIQNNAVENRDHSELAAPATRGISLSALLGGVSTIVSRAYQTGVWVMVEVEELYTVSGHIYLGVSERDHNGGVLAKSQAVIWQRTAQTILPKFQSDTGIQFAPGMKILVRGRPIYHQRYGFTITIDNIDSEYTLGELAAKKRKIRERLKTEGVFTANKQLPYPWDFNVVLVIAPAGGAGLGDFQAEAERLEQFGICHFDYIYSRFQGEGAAREICDKLQKAMSIYISQNNTLPDAVVIIRGGGPVNDIAWLNDYDLARYICDLPVPALTGIGHERDSTVLDEVANCKYDTPSKVIAGIEQTIKQRTSDAKIIFEQLINTGIRYIQESKLNTTLLDTEVRRNAMQQLTQGRKTTLALINEMKLNALNEIRIASDLSAGALQFIKTEAKVHVQQAKQSVPTLWNQIVNDANHSLKAASASTFMMATTVLDNARIEAAIARNVTKDSMEIIGTSAKQIVQSAKNDSKALMREIVGQGPEKTLKRGFAIIRNQEGKPITRAAQTVTGSTIEIQFIDANVSANIDQ
>NC_022576.1|WP_022771754.1|888866_889202_+|exodeoxyribonuclease-VII-small-subunit
MNATFKAAYKTLKTNADTLRKQHEPNIDDLLQIVTESVAAYKICQERINAVEKALEKALHDADTPTSEAPKGEQVAQHSSPPKQDEKIDDDIDEDDIDEETDYSYDKDVPF
>NC_022576.1|WP_041193233.1|889441_889696_+|hypothetical-protein
MKSYDSDHRHRRAARKGMDGEYFGIHNSKLHKILKNKLGPAANAYLIADGGTCPYRYQLGLSADTIAVEATMVEEGNGKSDDTL
>NC_022576.1|WP_041193235.1|890049_891132_+|hypothetical-protein
MKNSINAHRSFSGKEEAPLHLLVEREKKLHQLHVELPVRIKLLNNGSLIQITYNNIVLLGAVCRQLIHQIGSRAWGYSLDYQKISKNWSEKFSSNCIALEQELESVFDRFDLTIRYEKDRIGNNKIYGIVSPNFVNVNQIDFREQFLSKIKKSTYLTPISNGMKFDRYNRVIETFDFNNPDYQTSYSYGLVYAKNNGYESYKVNWERTILICTNGLTAIESNESIWKHTKDIDLHDFITQTVQVGIINQKHIEERIELSQNSLLHRSTFDELMRRLSLSNASKNRIQSRLAIESNAVGNNQWALSQSLTWLGTHEKAIPIRNQEQLTRLGTDILESSLEHVLEQPPQIMRDQSYGLVMPK
>NC_022576.1|WP_022771758.1|891186_891849_+|hypothetical-protein
MFREICLVCPNDKHYRKWLKDNNFISDPKRIPCPFAHEYHLQLYKLENIIRSIIKLHLEECPNRILQWNNRNKYGRYRIHYRELDYVYAPDQTPRLFIEIKHRETTTTGKDGIAQIKKSLFIAQHAWQNVSGVCINVMMADILGIETDIIPDFIPLTEIPTVLASESQPHDEIHVLWLDSKEVATFAIEHGLLTKEEVDDLPRLHKLARNPTKYLNTEFE
>NC_022576.1|WP_022771759.1|892042_893251_+|DUF1887-family-protein
MPKYATHLCLVSDQATPNLLPVLDPTWQPRKVVLARSKQMVDRAEALAKVLRPRCHGIEIAMRDLPDAYDYAALSDNFLDFLAGCEGEDVALNVTGGTKLMAVAAQEVFRSEGKPVFYVNVQTDEVIVIGQSARWQPLVSKLTVREMLEVHGHTVSPIRQIQVTAPQRDVTARLLDHLQSAAEAFGTLNYLAQLAEGKPGLTTQIDKKNSKWKALQALLFLLEDAQMLRLDGDKLTFADEEARRFVQGEWLEKHVYQTLQGLQGKYASISDVVTGVELEFDQRSRRTGKPLTRNEIDVACLYHNTLHLIECKTANYAKEPGDQDDKAATVLYKLESLQKLGGLRTKTMIVDLRGHLADQDANRNRAEESNILIVHGRELHDLRNVLERKWFSKGGEGKGTHA
>NC_022576.1|WP_187292329.1|893243_893390_+|hypothetical-protein
MPDRNILLCTLCASWAVIPEVFGWLAPAMLDLYAQHPANVSKTCPKYG
>NC_022576.1|WP_022771760.1|893575_893728_-|sigma-70-family-RNA-polymerase-sigma-factor
MPALRITMRKLKDALRLQFEGGKSHQQIAHALGISKGAVTKYVGLAGAYE

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Crispr_ID: NC_022576_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022576_2

884646-885590

TypeIII

Consensus_repeat	Method
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	PILER-CR
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CRISPRCasFinder
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CRT

13 spacers

cas2,cas1,cmr6gr7,cmr5gr11,cmr4gr7,csx1

The CRISPR arrays of NC_022576_2

>merge|NC_022576|2|884646-885590|PILER-CR,CRISPRCasFinder,CRT
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACAGAGACCAACTCTTCTGTCTTATTCATAAAAAAGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACGGTAGCTTCAGCAGCTACCACACCCGCTCCCGCAGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACCCCCTTTTCAGGAAGTGTATCGAAATCTGGTTCAGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACATCTAAACCAGTAAGATAACCAGTAGGAATACCGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACATACTCTACCCACTTAGCGGTGTCTCCGCCAGCGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACCCATCTGCCCGTTCAAATTGGGCCTGAGATTGAGGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACTCTTCCAATGCATAGAAAAATGAGGCCATTACGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACATTTTTGGCTTACCTAGCCTTCGCCACTCTTTGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACGTAGCGATATTTCGTTATTGAGCTTTGGCTGGGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACTCCTCTTTAACTTGAGTAGGATAATCAGAGCGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACTTCCAAAGATCTCTCATGAGATCCTCCTTCGGAGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACCATGCCAAAGGCACAGTCCGCCGACGAGCTTGAGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGACACTACTAGACCGACATCCTCCAGCGCGTAGAAGGTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAA

>NC_022576|2|2|884646-885590|PILER-CR
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AGAGACCAACTCTTCTGTCTTATTCATAAAAAA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GGTAGCTTCAGCAGCTACCACACCCGCTCCCGCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCCCTTTTCAGGAAGTGTATCGAAATCTGGTTCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ATCTAAACCAGTAAGATAACCAGTAGGAATACC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ATACTCTACCCACTTAGCGGTGTCTCCGCCAGC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCATCTGCCCGTTCAAATTGGGCCTGAGATTGAG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TCTTCCAATGCATAGAAAAATGAGGCCATTAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ATTTTTGGCTTACCTAGCCTTCGCCACTCTTT
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GTAGCGATATTTCGTTATTGAGCTTTGGCTGG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TCCTCTTTAACTTGAGTAGGATAATCAGAGC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTCCAAAGATCTCTCATGAGATCCTCCTTCGGA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CATGCCAAAGGCACAGTCCGCCGACGAGCTTGA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ACTACTAGACCGACATCCTCCAGCGCGTAGAAG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAA

>NC_022576|2|2|884646-885590|CRISPRCasFinder
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AGAGACCAACTCTTCTGTCTTATTCATAAAAAA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GGTAGCTTCAGCAGCTACCACACCCGCTCCCGCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCCCTTTTCAGGAAGTGTATCGAAATCTGGTTCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ATCTAAACCAGTAAGATAACCAGTAGGAATACC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ATACTCTACCCACTTAGCGGTGTCTCCGCCAGC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCATCTGCCCGTTCAAATTGGGCCTGAGATTGAG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TCTTCCAATGCATAGAAAAATGAGGCCATTAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ATTTTTGGCTTACCTAGCCTTCGCCACTCTTT
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GTAGCGATATTTCGTTATTGAGCTTTGGCTGG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TCCTCTTTAACTTGAGTAGGATAATCAGAGC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTCCAAAGATCTCTCATGAGATCCTCCTTCGGA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CATGCCAAAGGCACAGTCCGCCGACGAGCTTGA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ACTACTAGACCGACATCCTCCAGCGCGTAGAAG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAA

>NC_022576|2|2|884646-885590|CRT
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	AGAGACCAACTCTTCTGTCTTATTCATAAAAAA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GGTAGCTTCAGCAGCTACCACACCCGCTCCCGCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCCCTTTTCAGGAAGTGTATCGAAATCTGGTTCA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ATCTAAACCAGTAAGATAACCAGTAGGAATACC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ATACTCTACCCACTTAGCGGTGTCTCCGCCAGC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CCATCTGCCCGTTCAAATTGGGCCTGAGATTGAG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TCTTCCAATGCATAGAAAAATGAGGCCATTAC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ATTTTTGGCTTACCTAGCCTTCGCCACTCTTT
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	GTAGCGATATTTCGTTATTGAGCTTTGGCTGG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TCCTCTTTAACTTGAGTAGGATAATCAGAGC
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	TTCCAAAGATCTCTCATGAGATCCTCCTTCGGA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	CATGCCAAAGGCACAGTCCGCCGACGAGCTTGA
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAC	ACTACTAGACCGACATCCTCCAGCGCGTAGAAG
GTCTAAAGACATGCCCTGATCTCAAAGGGATTAAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_022576.1\|WP_081699919.1\|883718_884552_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NC_022576.1\|WP_022771745.1\|878040_878316_+\|DUF1778-domain-containing-protein	unknown	unknown	gnl\|CDD\|370057
NC_022576.1\|WP_022771758.1\|891186_891849_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022771752.1\|885784_886927_+\|TIGR02584-family-CRISPR-associated-protein	csx1	pfam09623_csx1_CAS-III	gnl\|CDD\|187872
NC_022576.1\|WP_022771750.1\|880856_882329_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022771747.1\|878947_879232_+\|CRISPR-associated-protein-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_022576.1\|WP_041193235.1\|890049_891132_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022771749.1\|880344_880680_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
NC_022576.1\|WP_022771746.1\|878316_878820_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NC_022576.1\|WP_022771753.1\|887120_888848_+\|exodeoxyribonuclease-VII-large-subunit	unknown	unknown	gnl\|CDD\|234714
NC_022576.1\|WP_041193233.1\|889441_889696_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022771754.1\|888866_889202_+\|exodeoxyribonuclease-VII-small-subunit	unknown	unknown	unknown
NC_022576.1\|WP_022771759.1\|892042_893251_+\|DUF1887-family-protein	csx1	pfam09002_csx1_CAS-III	gnl\|CDD\|312526
NC_022576.1\|WP_022771743.1\|876001_876565_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl\|CDD\|378242
NC_022576.1\|WP_022771760.1\|893575_893728_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NC_022576.1\|WP_022771748.1\|879298_880270_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_022576.1\|WP_187292329.1\|893243_893390_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022771742.1\|875012_875990_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NC_022576.1\|WP_041193238.1\|894105_894372_+\|DUF4160-domain-containing-protein	unknown	unknown	gnl\|CDD\|379344
NC_022576.1\|WP_187292328.1\|876644_877898_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|224520

Protein	Function_ID	Function_description	E-value
NC_022576.1\|WP_081699919.1\|883718_884552_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.70965e-21
NC_022576.1\|WP_022771745.1\|878040_878316_+\|DUF1778-domain-containing-protein	gnl\|CDD\|370057	pfam08681, DUF1778, Protein of unknown function (DUF1778). This is a family of uncharacterized proteins. The structure of one of the hypothetical proteins in this family has been solved and it forms a helix structure which may form interactions with DNA.	2.64327e-20
NC_022576.1\|WP_022771753.1\|887120_888848_+\|exodeoxyribonuclease-VII-large-subunit	gnl\|CDD\|234714	PRK00286, xseA, exodeoxyribonuclease VII large subunit; Reviewed.	5.41353e-80
NC_022576.1\|WP_022771747.1\|878947_879232_+\|CRISPR-associated-protein-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.44357e-08
NC_022576.1\|WP_022771749.1\|880344_880680_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	6.82038e-22
NC_022576.1\|WP_022771746.1\|878316_878820_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.96941e-08
NC_022576.1\|WP_022771752.1\|885784_886927_+\|TIGR02584-family-CRISPR-associated-protein	gnl\|CDD\|187872	cd09741, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	2.37732e-81
NC_022576.1\|WP_022771759.1\|892042_893251_+\|DUF1887-family-protein	gnl\|CDD\|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	6.12523e-64
NC_022576.1\|WP_022771743.1\|876001_876565_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	1.23608e-33
NC_022576.1\|WP_022771760.1\|893575_893728_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	0.00130447
NC_022576.1\|WP_022771748.1\|879298_880270_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.05721e-84
NC_022576.1\|WP_022771742.1\|875012_875990_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	1.96984e-63
NC_022576.1\|WP_041193238.1\|894105_894372_+\|DUF4160-domain-containing-protein	gnl\|CDD\|379344	pfam13711, DUF4160, Domain of unknown function (DUF4160).	1.06732e-23
NC_022576.1\|WP_187292328.1\|876644_877898_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|224520	COG1604, COG1604, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	9.87745e-20

>NC_022576.1|WP_081699919.1|883718_884552_-|IS5-family-transposase
MGLIFHDDGWRLHDALWGIIKSSLPEPKKHPLGCHNPRVSDRSAMNAILFVLRTGCQWNALNMTGICSCSSAYRRFREWTKAGVFSALWIQQLVEYDKSQGIDWAWTSMDGALTKAPLAGQQTTGANPTDRGKQGVKRSVLTDGAGIPLAVAIDGANRHDMKLVRSTLEDIKAKRPDPTDTKPQGICLDKGYDFDEVREIVKEFGFTAHIRSRGEEAKSIKQEAGFKARRWVVERTHSWMNRFRRILVRWEKLPETYIAMLHLTCALITLRAYCLLK
>NC_022576.1|WP_022771750.1|880856_882329_+|hypothetical-protein
MISITHKIIEDTMNSREIFTLRKQGRSAEALQIAREAYPGNENDLWLLRAYAWSMYDHVKSIIDRCEAKKISPYTIGSRLSPLMREFLHIANPLRSDSVFSHMNRLALKSSRYWPDFLGYARWVGADNFTGEDKKPFVTQEGKIVESFYKRYIRAICRETAAKATDKQTRPQWIEWGSQILKRSLKIEPNDLWFNYYQSKLHLAQGQPDLALQRLIPVLLQHSTAAWPWGLLGDIFETTRPEDTLICYAYATQLARKEIEVAKIRIQLAQRLALVERYNEAANQAWLAIQYRKINGYRIPQGLQNILANNWYHDAVANNTLQPLPPMHSVACKILQELHRQRLTYTRGVIDQNHSTNALTFLATGTESGIGLWNKKFPEIAKLPSGTVIEIGRRETDGPPLDWKISELQEITGLCQAFSGTVIRQADKDFAFVRCELGDVFVPPELAKNFDPVQQYNVKGKAMRKINKQGKSCWSAIHCILQDLYINQAL
>NC_022576.1|WP_022771749.1|880344_880680_+|CRISPR-associated-endonuclease-Cas2
MGTKLKNKYIIAYDICDPKRYNKIHKIIKKYGLPLQYSVYLLDVTRLEIEKLVTELRSLIDPEKDDIRGYYIPQNTWKVSMGTSIVPNDVLPGLWKDQTTAEQDDQYALFT
>NC_022576.1|WP_022771748.1|879298_880270_+|CRISPR-associated-endonuclease-Cas1
MALLVLDRTELDIRVDGDALALYESGTRRGTVPIKLMDRCVIHGARTKLDTGVLQRLAEAGVTTVLISPRAQRRAAIVLGNQHNDAAVRIAQALRVMNQQECWQWSAGIVRAKLARQRKTLSLMQQERPDARKPLFDAIQTIDSIQAHLREFGATTGAVASIRGWEGAAARAYFAALGSVFPPALGFAGRNRRPPKDPVNVCLSLSYTMLHAQAIQQCTITGLDPMLGFYHRPAFGRESLASDLIEPLRPAVDAWVWELLRKRVLREDHFSTNETGCMMGKAGRQIYYTEWEENQKPWQRWLRAQCQNLAKTLRNKGSLCLAE
>NC_022576.1|WP_022771747.1|878947_879232_+|CRISPR-associated-protein-Cas2
MAQRLFHLACYDVAKPRRLKAALKLTRAYATGGQKSVHEIFLTAEERAALLADMALLLDPEEDRFLLLRLDPRSHVYTLGKAMQPADPDYFYVG
>NC_022576.1|WP_022771746.1|878316_878820_+|GNAT-family-N-acetyltransferase
MSGYSIRPLDSEADTARFDCGDAALNDYLRRYATQDVRRNVTRAFIASPLESSTRIAGFFTLSAASIQAETLPENLRKKLPRYPVPVALLGRLAVDREFQGKGLGSILLADVCRKVHAASRTLAVAGIVVDAKSPSASTFYQHFGFLELPGQTSRLILPSSGFADRG
>NC_022576.1|WP_022771745.1|878040_878316_+|DUF1778-domain-containing-protein
MTATVKDTRLHIRCNQQVRHLLDKAAAHSHMSVSEFVLQNAVHHAQAVLAAHETITLSQEDFALFLKALDTPVTPNAALQRAFACHDEQVR
>NC_022576.1|WP_187292328.1|876644_877898_+|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIYQNDVCNPKEKKHFLEKSCPLPPSSVKTVEALIQRQTALVATYGANGLHWHTTSTAPFATGLGNEHPIENGFAFLTPYGLPYLAGSGFKGILRRAAEELALDNDTQNDDGWTWVDIWWLFGFEGAVNKGSQWDSDSDLGHAFERDSYKLAANANLHELLQRLANIDKSMARYADSSDRTAAAQGFLQACLAGSTLRGGLQWRGAVDCWDVYPQPQGNRMVVEIMTPHHGPYYRGDSNPHDSHSPIPVNFLAVPAGSAFHFFAVCHAQKLPQGLQNRWRALLDAAMHHACEWVGFGAKTSVGYGAMQKPAPLPQPAPAKEPRAATTSTEQPIAPVEEGIIWQEATLTYSRNTSEITAGNPPKKTKPLKGDLAKAFLNALPEKQRTRLTKDGAFRNVPVVVKQDGNTWELLRPATTG
>NC_022576.1|WP_022771743.1|876001_876565_+|type-III-B-CRISPR-module-associated-protein-Cmr5
MNQHANQPRAKLTTNKNPQDGNKASTLNPQRTESRTASEPYPGKRRHSTEPSPTGGGQGEGTPQTLDQQRAKLAWGYAQEGIKQYGSDYKNLAKGAPALIMGSGLMPTMAFYEGKKSDPAKALLRHLICGLHERIPTINHQEKDFPSFMKYLQNSLSQDYLRATDEALELLKWIRQFVDALGGDSNA
>NC_022576.1|WP_022771742.1|875012_875990_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MFTATRLAFYAAVSPVHMGAGSAIGAIDSPIQREVHTQHPSFAGSGLKGALRHHFANQWPREGDKPNGLIARIFGPDTNASDYAGALSLTDAQLVALPVRSLRNGFAYVTSPLALARLRRLALQAGVECGWEVPTVPQAGQALLSGAGLADKDQLVLEAFEFRPAKVEPLLANIAQWIAKHALAGAGNQYFQQKFCEDLVLLHDTDFSHFARHGMVVEPHVRINDQTGTADGGGLFYVENLPPESLLVGLVQASDEHRAKPKAGEDGAAALPRLGALDILTAVLNGTTEQPGIHGKVLQIGGDATTGRGLVLVQCAPQEPNQPKA
>NC_022576.1|WP_022771752.1|885784_886927_+|TIGR02584-family-CRISPR-associated-protein
MNSYDPHQPAGYPRRVLIAVSGLSPQIVTETIYALAADQDEAFVPTEVHLLTTATGAQRAELSLLSEDLGWFHKLQADFHLPGIAFDRSHIHVMRDAQGKPLGDIRTPADNQAAADFITAQVRAFTADDACALHASIAGGRKTMGFYLGYALSLYGRAQDRLSHVLVSEPFESSYDFFYPTPYSRVLRLLNNQLADSVNAQVTLANIPFVSLRHGLPSALLAGTASFNDTVEAAIAALAPPRLRLHLRGQYIVAGTTRIALPPAELALLAVFARRAEMGKEPLPAPAKGVPDKDWATIYLREYRRITGNDAENQDPTHRALRKGMDGEYFSIHKSRLHKTLKNTLGPSANAYLIADGGTRPRLYQLALNADAIAFEETVV
>NC_022576.1|WP_022771753.1|887120_888848_+|exodeoxyribonuclease-VII-large-subunit
MANTYLIVTYSEKDAAKALGAKWDSVQRSWYVPEGRELAPFSQWLPKDGVATKATIQNNAVENRDHSELAAPATRGISLSALLGGVSTIVSRAYQTGVWVMVEVEELYTVSGHIYLGVSERDHNGGVLAKSQAVIWQRTAQTILPKFQSDTGIQFAPGMKILVRGRPIYHQRYGFTITIDNIDSEYTLGELAAKKRKIRERLKTEGVFTANKQLPYPWDFNVVLVIAPAGGAGLGDFQAEAERLEQFGICHFDYIYSRFQGEGAAREICDKLQKAMSIYISQNNTLPDAVVIIRGGGPVNDIAWLNDYDLARYICDLPVPALTGIGHERDSTVLDEVANCKYDTPSKVIAGIEQTIKQRTSDAKIIFEQLINTGIRYIQESKLNTTLLDTEVRRNAMQQLTQGRKTTLALINEMKLNALNEIRIASDLSAGALQFIKTEAKVHVQQAKQSVPTLWNQIVNDANHSLKAASASTFMMATTVLDNARIEAAIARNVTKDSMEIIGTSAKQIVQSAKNDSKALMREIVGQGPEKTLKRGFAIIRNQEGKPITRAAQTVTGSTIEIQFIDANVSANIDQ
>NC_022576.1|WP_022771754.1|888866_889202_+|exodeoxyribonuclease-VII-small-subunit
MNATFKAAYKTLKTNADTLRKQHEPNIDDLLQIVTESVAAYKICQERINAVEKALEKALHDADTPTSEAPKGEQVAQHSSPPKQDEKIDDDIDEDDIDEETDYSYDKDVPF
>NC_022576.1|WP_041193233.1|889441_889696_+|hypothetical-protein
MKSYDSDHRHRRAARKGMDGEYFGIHNSKLHKILKNKLGPAANAYLIADGGTCPYRYQLGLSADTIAVEATMVEEGNGKSDDTL
>NC_022576.1|WP_041193235.1|890049_891132_+|hypothetical-protein
MKNSINAHRSFSGKEEAPLHLLVEREKKLHQLHVELPVRIKLLNNGSLIQITYNNIVLLGAVCRQLIHQIGSRAWGYSLDYQKISKNWSEKFSSNCIALEQELESVFDRFDLTIRYEKDRIGNNKIYGIVSPNFVNVNQIDFREQFLSKIKKSTYLTPISNGMKFDRYNRVIETFDFNNPDYQTSYSYGLVYAKNNGYESYKVNWERTILICTNGLTAIESNESIWKHTKDIDLHDFITQTVQVGIINQKHIEERIELSQNSLLHRSTFDELMRRLSLSNASKNRIQSRLAIESNAVGNNQWALSQSLTWLGTHEKAIPIRNQEQLTRLGTDILESSLEHVLEQPPQIMRDQSYGLVMPK
>NC_022576.1|WP_022771758.1|891186_891849_+|hypothetical-protein
MFREICLVCPNDKHYRKWLKDNNFISDPKRIPCPFAHEYHLQLYKLENIIRSIIKLHLEECPNRILQWNNRNKYGRYRIHYRELDYVYAPDQTPRLFIEIKHRETTTTGKDGIAQIKKSLFIAQHAWQNVSGVCINVMMADILGIETDIIPDFIPLTEIPTVLASESQPHDEIHVLWLDSKEVATFAIEHGLLTKEEVDDLPRLHKLARNPTKYLNTEFE
>NC_022576.1|WP_022771759.1|892042_893251_+|DUF1887-family-protein
MPKYATHLCLVSDQATPNLLPVLDPTWQPRKVVLARSKQMVDRAEALAKVLRPRCHGIEIAMRDLPDAYDYAALSDNFLDFLAGCEGEDVALNVTGGTKLMAVAAQEVFRSEGKPVFYVNVQTDEVIVIGQSARWQPLVSKLTVREMLEVHGHTVSPIRQIQVTAPQRDVTARLLDHLQSAAEAFGTLNYLAQLAEGKPGLTTQIDKKNSKWKALQALLFLLEDAQMLRLDGDKLTFADEEARRFVQGEWLEKHVYQTLQGLQGKYASISDVVTGVELEFDQRSRRTGKPLTRNEIDVACLYHNTLHLIECKTANYAKEPGDQDDKAATVLYKLESLQKLGGLRTKTMIVDLRGHLADQDANRNRAEESNILIVHGRELHDLRNVLERKWFSKGGEGKGTHA
>NC_022576.1|WP_187292329.1|893243_893390_+|hypothetical-protein
MPDRNILLCTLCASWAVIPEVFGWLAPAMLDLYAQHPANVSKTCPKYG
>NC_022576.1|WP_022771760.1|893575_893728_-|sigma-70-family-RNA-polymerase-sigma-factor
MPALRITMRKLKDALRLQFEGGKSHQQIAHALGISKGAVTKYVGLAGAYE
>NC_022576.1|WP_041193238.1|894105_894372_+|DUF4160-domain-containing-protein
MPIISMFYGIIIRLYLIDNQHHNLPHIHARYAEFEASIGLGDGEILAGELPRKQLRLVQAWIELHRDELMANWELAVSGENPYKIEPL

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Crispr_ID: NC_022576_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022576_3

1988160-1988321

Orphan

Consensus_repeat	Method
CAGTACGGCAAGTGGGTACAACAACGCTGGGGCGGTTTTGCGTAAGTCTAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022576_3

>merge|NC_022576|3|1988160-1988321|CRISPRCasFinder
CAGTACGGCAAGTGGGTACAACAACGCTGGGGCGGTTTTGCGTAAGTCTAGGAAAAATAAGACTTACGCAAAATTGTCCCGGCTAGGCGTACCCACGCAGACAGTACAAAACAGTACGGCAAGTGGGTACAACGACGCTGGGGCGGTTTTGCGTAAGTCTAG

>NC_022576|3|3|1988160-1988321|CRISPRCasFinder
CAGTACGGCAAGTGGGTACAACAACGCTGGGGCGGTTTTGCGTAAGTCTAG	GAAAAATAAGACTTACGCAAAATTGTCCCGGCTAGGCGTACCCACGCAGACAGTACAAAA
CAGTACGGCAAGTGGGTACAACGACGCTGGGGCGGTTTTGCGTAAGTCTAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_022576.1\|WP_022774307.1\|1994986_1995772_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022774261.1\|1985959_1986214_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369507
NC_022576.1\|WP_081699853.1\|1984798_1985911_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133030
NC_022576.1\|WP_022774255.1\|1980772_1982128_+\|lipopolysaccharide-biosynthesis-protein-RfbH	unknown	unknown	gnl\|CDD\|237960
NC_022576.1\|WP_187292354.1\|1982597_1984760_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645
NC_022576.1\|WP_022774248.1\|1978864_1979638_+\|glucose-1-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|131672
NC_022576.1\|WP_022774318.1\|1997192_1999064_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_022576.1\|WP_022774322.1\|1999121_2001056_+\|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl\|CDD\|225118
NC_022576.1\|WP_022774276.1\|1988455_1989487_-\|S49-family-peptidase	unknown	unknown	gnl\|CDD\|132934
NC_022576.1\|WP_022774310.1\|1995797_1997069_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022774252.1\|1979598_1980798_+\|CDP-glucose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|187562
NC_022576.1\|WP_022774299.1\|1993999_1994311_+\|J-domain-containing-protein	unknown	unknown	gnl\|CDD\|274090
NC_022576.1\|WP_022774294.1\|1991175_1993947_+\|Rne/Rng-family-ribonuclease	unknown	unknown	gnl\|CDD\|236766
NC_022576.1\|WP_187292353.1\|1976010_1977360_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|270426
NC_022576.1\|WP_022774269.1\|1987330_1987978_-\|DUF47-domain-containing-protein	unknown	unknown	gnl\|CDD\|224310
NC_022576.1\|WP_022774290.1\|1990796_1991165_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022774265.1\|1986305_1987319_-\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541
NC_022576.1\|WP_022774279.1\|1989533_1990508_-\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|182909
NC_022576.1\|WP_022774303.1\|1994423_1994975_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022774245.1\|1977455_1978544_-\|FkbM-family-methyltransferase	unknown	unknown	gnl\|CDD\|273628

Protein	Function_ID	Function_description	E-value
NC_022576.1\|WP_022774261.1\|1985959_1986214_-\|hypothetical-protein	gnl\|CDD\|369507	pfam07769, PsiF_repeat, psiF repeat. This region is approximately 35 residues long. It is found repeated in a number of putative phosphate starvation- inducible proteins expressed by various bacterial species. psiF is known to be an example of such phosphate starvation-inducible proteins.	5.61921e-09
NC_022576.1\|WP_081699853.1\|1984798_1985911_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	8.27245e-82
NC_022576.1\|WP_022774255.1\|1980772_1982128_+\|lipopolysaccharide-biosynthesis-protein-RfbH	gnl\|CDD\|237960	PRK15407, PRK15407, lipopolysaccharide biosynthesis protein RfbH; Provisional.	0
NC_022576.1\|WP_187292354.1\|1982597_1984760_+\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	6.56742e-116
NC_022576.1\|WP_022774248.1\|1978864_1979638_+\|glucose-1-phosphate-cytidylyltransferase	gnl\|CDD\|131672	TIGR02623, Glucose-1-phosphate_cytidylyltransferase, glucose-1-phosphate cytidylyltransferase. Members of this family are the enzyme glucose-1-phosphate cytidylyltransferase, also called CDP-glucose pyrophosphorylase, the product of the rfbF gene. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	8.98784e-169
NC_022576.1\|WP_022774318.1\|1997192_1999064_+\|sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.29073e-57
NC_022576.1\|WP_022774322.1\|1999121_2001056_+\|SpoIIE-family-protein-phosphatase	gnl\|CDD\|225118	COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription].	3.90241e-22
NC_022576.1\|WP_022774276.1\|1988455_1989487_-\|S49-family-peptidase	gnl\|CDD\|132934	cd07023, S49_Sppa_N_C, Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad. Signal peptide peptidase A (SppA; Peptidase S49; Protease IV): SppA is found in all three domains of life and is involved in the cleavage of signal peptides after their removal from the precursor proteins by signal peptidases. This subfamily contains members with either a single domain (sometimes referred to as 36K type), such as sohB peptidase, protein C and archaeal signal peptide peptidase, or an amino-terminal domain in addition to the carboxyl-terminal protease domain that is conserved in all the S49 family members (sometimes referred to as 67K type), similar to E. coli and Arabidopsis thaliana SppA peptidases. Site-directed mutagenesis and sequence analysis have shown these SppAs to be serine proteases. The predicted active site serine for members in this family occurs in a transmembrane domain. Mutagenesis studies also suggest that the catalytic center comprises a Ser-Lys dyad and not the usual Ser-His-Asp catalytic triad found in the majority of serine proteases. Interestingly, the single membrane spanning E. coli SppA carries out catalysis using a Ser-Lys dyad with the serine located in the conserved carboxy-terminal protease domain and the lysine in the non-conserved amino-terminal domain.	6.73496e-82
NC_022576.1\|WP_022774252.1\|1979598_1980798_+\|CDP-glucose-4,6-dehydratase	gnl\|CDD\|187562	cd05252, CDP_GD_SDR_e, CDP-D-glucose 4,6-dehydratase, extended (e) SDRs. This subgroup contains CDP-D-glucose 4,6-dehydratase, an extended SDR, which catalyzes the conversion of CDP-D-glucose to CDP-4-keto-6-deoxy-D-glucose. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NC_022576.1\|WP_022774294.1\|1991175_1993947_+\|Rne/Rng-family-ribonuclease	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	0
NC_022576.1\|WP_187292353.1\|1976010_1977360_+\|diguanylate-cyclase	gnl\|CDD\|270426	cd13708, PBP2_BvgS_like_1, Putative sensor domain similar to BvgS; the type 2 periplasmic binding protein domain. BvgS is composed of two periplasmic domains homologous to bacterial periplasmic-binding proteins (PBPs), a transmembrane region followed successively by a cytoplasmic PAS (Per/ARNT/SIM), a Histidine-kinase (HK), a receiver and a Histidine phosphotransfer (Hpt) domains. The sensor protein BvgS can autophosphorylate and phosphorylate the response regulator BvgA. The BvgAS phosphorelay controls the expression of virulence factors in response to certain environmental stimuli in Bordetella pertussis. Its close homologs, Escherichia coli EvgS and Klebsiella pneumoniae KvgS, appear to be involved in the transcriptional regulation of drug efflux pumps and in countering free radical stresses and sensing iron limiting conditions, respectively. The periplasmic sensor domain of BvgS belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.93761e-111
NC_022576.1\|WP_022774269.1\|1987330_1987978_-\|DUF47-domain-containing-protein	gnl\|CDD\|224310	COG1392, COG1392, Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism].	8.29844e-38
NC_022576.1\|WP_022774299.1\|1993999_1994311_+\|J-domain-containing-protein	gnl\|CDD\|274090	TIGR02349, Chaperone_protein_DnaJ, chaperone protein DnaJ. This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.	8.45578e-28
NC_022576.1\|WP_022774265.1\|1986305_1987319_-\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	3.63597e-104
NC_022576.1\|WP_022774279.1\|1989533_1990508_-\|RluA-family-pseudouridine-synthase	gnl\|CDD\|182909	PRK11025, PRK11025, 23S rRNA pseudouridine(955/2504/2580) synthase RluC.	6.37071e-103
NC_022576.1\|WP_022774245.1\|1977455_1978544_-\|FkbM-family-methyltransferase	gnl\|CDD\|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	2.39045e-16

>NC_022576.1|WP_022774269.1|1987330_1987978_-|DUF47-domain-containing-protein
MLFGKLLPRNTDFFALFDQHADHIVEAAQAFSKLVEHYNDPELRSQYHRAVDHAEKAADRVTHEVNKAIHQTFITPIDREQIHGLINTMDDVADLIQDSAETMALYDVRGMTDEISRLTDLSLRCCSRVRDAVRLLARIADPATAEAALKTCDEIDLLEGDADRVMRTAMSKLFREEPDVRELIKLKAIYELLETITDRCEDVANLIEGIILENS
>NC_022576.1|WP_022774265.1|1986305_1987319_-|inorganic-phosphate-transporter
MPVSEVSLWIVVVLVSMAIAFDFMNGFHDAANSIATVVSTGVLKPGQAVVFAAFFNVIAILFFPLSVAATVGKGIVLPGVVDIYVVFGALTGAITWNLITWWYGIPSSSSHALIGGIAGAAIAKVGVQSLILPGIIKTVVFIFVSPLLGFLLGSLMMVLVSWIFRRTRPLRVDRWFRRLQLLSAGAYSLGHGGNDAQKTIGIIWMLLLATGYASHDDAAPAGWIIVSCYTAIGLGTMFGGWRIVKTMGQKLTKLKPVGGFCAETGGAVTLFTATALGIPVSTTHTITGAIIGVGSTRRPSAVRWGVAGNIVWAWIFTIPASAFVAAVAYWVSLGMLH
>NC_022576.1|WP_022774261.1|1985959_1986214_-|hypothetical-protein
MKSLLCIVGLGLTLWGTAHATEAAADAASAAEPAAATAKAKAPVSSAVQAQRNRMKACNQEARTQQLKGQPRRDFMKECLRKKD
>NC_022576.1|WP_081699853.1|1984798_1985911_-|glycosyltransferase-family-2-protein
MQGSSPPHPPSPAPIGAPSPAGRGQKIPFPSGRGARTQAIAPSIFPSIAPSISCVVPVYNEAGVVARVVADILAALVALSDRVELIAVDDGSRDGTYAELLALCAQHPQLVCLRLSRNFGKERALTAGIDAARGEVVVLMDGDGQHPTALLPVMFQQWRDGADVVYAVRQHRNDQSPLHARLTAWFYRLINLGSRVRIPPDAGDYRWMDRKVVDALKQLPERNRFMKGLYAWVGFQSVAIPYDPLPRSAGHSNFGLVSAFSLALTGMLAFSVTPLRVLTLAGLVLSCLALGYGAWVVAEYFLYGIAVPGFATIVVAIMFFSGVQLLATGILSEYVARIYEEVKRRPNYLIGERVGEGLDIKLPPPPVDLL
>NC_022576.1|WP_187292354.1|1982597_1984760_+|EAL-domain-containing-protein
MMSTGGMVRTIADITRYVQAQADRQHLERLSSEMQATAQVGAWDMDFANDTVTWTEGIYRILELSTTDYVPSLEAMRCFFPPQSLERIAIACDDTQLQPGSFDLELEMVTAKGNTIWVHMVGSTQWRFSLPMRRTAIVQDITERKRSEATWREDIARWKLALESTGDGMWDLDVRTGQEYFSPNLLRMYGFVEKDIDQSIHALDARTHPDDVPRMMRDRQAHLDGRTPVYRNEHRVRCKSGSWKWVLSRGMVISRDELGRPLRMIGTHTDITEHKAAEAQIWQQANFDTLTGLPNRRMLRSRLEQELKKCRRDGHKLTVAFVDLDHFKEVNDTLGHHHGDALLIQATQRILGCLREVDTVARMGGDEFTLLLTEIVDTRHIETILAKLLCTLGEAFLLDQQQVYVSASVGVTIYPDDATAIEDLFRNADQALYAAKDAGRNRFCYFTPELQHAAQRRVRLTNDLRAALAVEQFQVVYQPIVELATGHIHKAEALLRWEHPQRGSVSPGEFIPIAESSGLIVEIGEWVFQRALEQVCRWRQRLHPQFQVSVNKSPVQFEKVDLARSRWIDQIRQHGQEGNCLVVEITEGLLLSHSDEVIEQILALSDDGIQVSLDDFGTGYSSLAYLQKFDIDYIKIDQSFVRQLVGESTDLALCQAIIAMAHALNMQVIAEGVETAQQRDLLAAAGCDYGQGYLFSRPVRSEELEALVLRTNRGVTPMRV
>NC_022576.1|WP_022774255.1|1980772_1982128_+|lipopolysaccharide-biosynthesis-protein-RfbH
MDRILDIDEPTPPDRPQALRKHIAALVREYAQLVLAPPAFVPGITPVPPSGKLLGAEELEAMVEASLDGWLTTGRFNADFERRLARFVGVNHALTVNSGSSANLVAFFTLTSPKLGDRAIRKGDEVLTTAVGFPTTVNPIVQFGAIPVFVDVDPATYNVDVAQLEAAIGPRTKAVMLAHCLGNPFDLDAVTALCRKHGLWLVEDCCDALGSTYRGKMVGTFGDLATLSFYPAHHITMGEGGAVLTNDPTLRAIAESFRDWGRDCSCPPGRDNTCGKRYAQQLGTLPAGYDHKYTYSHLGFNLKITDMQAACALAQLAKAPGFIRSRKDHFAYLLDQLRPCEGLLQLPRATAYADPSWFGFALTLREDCPVSRVDLLSYLDQHRVGTRLVFAGNLTRQPSMQGVPYRIHGTLRHADAVMERSFWIGVQPALTTEMLDFAARAIERFLGVRFG
>NC_022576.1|WP_022774252.1|1979598_1980798_+|CDP-glucose-4,6-dehydratase
MGERESTVEAVELTSPPTSGNTVGGANTVGGTVREHSTVPADFWHGKRVFLTGHTGFKGSWLALWLQAMHAQVAGYALPAPTTPSLFELAQVASGMAHTIGDVCDLPTLHTAMAAHRSEIVFHLAAQPLVRRSYQEPVETYATNVMGTVHLLDCVRRVPSVRAVVVVTTDKCYDNREWPWPYRENEAMGGFDPYSSSKGCAELVTAAYRSSFFREGAVAVASARAGNVIGGGDWAPDRLIPDAMAAFAAGRTLTLRNPGATRPWQHVLEPLGGYLILAQALWEHGQDYAEAWNFGPHAEDAWPVAQVIDTLATLWGGTARWEVDKAMHPHEAHCLQLDIAKARARLRWQPRLRLQQALEHTVDWYRRLHAGEDARELTLQQLQRYRSEDPTHGSHSGHR
>NC_022576.1|WP_022774248.1|1978864_1979638_+|glucose-1-phosphate-cytidylyltransferase
MKAVILAGGLGTRLSEETVVRPKPMVEIGGHPLLWHLLKIYSCHGIHDFVICCGYKGYLIKEFFANYFLHTSDVTFHMQTNKMEVHHQHAEPWNVTLVDTGEHTMTGGRLLRVAEYVRNEEAFCLTYGDGLGDVDIAETIRFHHSHGKLATVTAALPPGRFGALDIQDGQVLHFREKPRGDGAVVNGGFFVLSPGVLDYLADDATIWEQEPLRQLAQDGQLMAYRHTGFWQPMDTLYDKRSLEALWESGKAPWKLWN
>NC_022576.1|WP_022774245.1|1977455_1978544_-|FkbM-family-methyltransferase
MQTVIAQLYQDLDGRIPGMTGQAGQKTEKKTGNIAGTGNKAANKTGRNTRNNPGKETGNKTNALLNNAHVVQIQNKARKAGIQVKLAAHYVDFIKDGKILRISLKHFIYSYDMIDSFDYYFSSVEPMEFQGYELVDYSTPRYHHVVGFGLMPIHFPSLSEPVATTYQYLEFADLKAGQNVIDLGAYAGLTSIIFKEFVGSTGRVIALDADQYNLQSIQKNIDLYTRIRGDVIEAFAGAIWNHGNGLSFSSEGNMGAAVSHILGANRGDTQVVESVTLSGLMQVADLPSVDFIKCDVEGAESVVFEDREFFANHRPKIVIETHLVNGSATADKCIQDLSAYGYTCTKVAQVGATLPLIECRPS
>NC_022576.1|WP_187292353.1|1976010_1977360_+|diguanylate-cyclase
MAGSALAGAQDPEIALTPEEREYLRRIPAIKMCVDPDWTPFEHIDKQGRHVGIAADLVQRVAQRVGLRIDLYPTKTWEESVAASKVGHCHILSFLNQTPSREEWLSFTDPIFYDQNIIITREEHPYIGDIRGLKDERVALPGGTMVEERIRRDFPNLVIVTTGSESEAVSLVSERKAELTVRSLIVAAYAIKKEGLFNLKIAGQIPEYSNKLRIGVRKEEPLLRSILDKGVQTITPQDREAIANRHVSVQVYSNFDTTLLWQVGAVALVVIALVLYWNRKLQAINREFERLSITDRLTGLYNRLRLDTVLEAEVQRSSRFGQPFSVILLDIDHFKAVNDEYGHHTGDDVLIEVARILQTHTRETDVVGRWGGEEFLVVCPHTHREGARTLAENLRSKMQERDIPTVGHKTASFGVAAYEAKDHAKDVVARADTALYEAKRNGRNRVEAG
>NC_022576.1|WP_022774276.1|1988455_1989487_-|S49-family-peptidase
MSEDTDPDASTAQPAPARATKALAEEVPPPGWERAILEKLVLATLQEQRSARRWRTFVRLAWLGFFVVVVWLGFQQSVDKPGESPAHTAVVHIKGEIAADTVASAELLVPSLRSAFEDAGARAVVLRVNSPGGSPVQAGIVHDEILRLKALHKKPVYAVVEESCASAAYYIAVAADHIYVDKASIVGSIGVLFDGFGFTGVMEKIGIERRLLTAGGNKGILDPFSPETPEHRAFAQSLLDQIHRQFIAVVKAGRGTRLKDQQDGSDVFTGLFWNGEQAIALGLADQLGSLDYVAREVVHAEDIVDYTRQENVAERLVKRFGLAVGQGIARSVAPHPALRGMAP
>NC_022576.1|WP_022774279.1|1989533_1990508_-|RluA-family-pseudouridine-synthase
MPLAASPTWLVVDEESAGQRLDNYLVRLLKGVPKTRIYRMIRSGEVRVNGKRAAVGDRLEVGAALRLPPVRVAQAESKPAMAPAREPPILWEDDVLLAIDKPSGLAVHGGSGVRFGVIEQLRAARPAQRFLELVHRLDRDTSGVLLVSKKRSVLTHLHEQFRNRQTAKTYLAMVRGPWPQTLRVLDSPLRTLPAGDNGERRVCIATTEDPYARESLTLVRVCAACAEYSLLEVQIKTGRMHQIRVHLAAQGHPILGDDKYGDFALNKALAAAYPGLRRCFLHAWRLRFLHPRSGERMSLVADLPEELQAFVAAAFPALPPLAAS
>NC_022576.1|WP_022774290.1|1990796_1991165_+|hypothetical-protein
MTLQPRGNTHPVRIAAGCASSTPGRQRPRGPVSLYNDLYNGLYGLHRLHDLHGLSPPLHPLYIRCAAMVFSRRPSSGLSVGMVPSLDRYVVVAQSVLCGLRYSPRWFRYFACHIWHAPQPGS
>NC_022576.1|WP_022774294.1|1991175_1993947_+|Rne/Rng-family-ribonuclease
MKRMLINATQAEERRLAVVDGQKLLDYEIEIEGREQRKGNIYKAIVTRIEPSLEACFVDYGEDRHGFLPFKEVARQYFQQGIPTGQAKISEALKEGQELLVQVEREERGNKGAALTTFVSLAGRYIVLMPNNPRGGGVSRRVEGDDRTDLKEALDQLEYPNGMSIIARTAGIGRNAVELQWDLSYLLKLWSAIDAAAKGSKGPLLIYQESNLVIRAIRDYFHQEIGEILIDTDDVYEQARQFMAHVMPEHAPRVKRYRDDAPLFSRFQIEHQIETAYARTVTLPGGGAIVIDHTEALVSIDVNSARAIKGSDIEETALRTNLEAAEEVARQARLRDLGGLIVIDFIDMEESRNRREVETRLRDSLRQDRARVQFGTISRFGLMEMSRQRLRPALSEGASMPCPRCGGSGHVRDTESSALQILRIVQEESHKDNTASVLCQVPVDVASFLLNEKRTEIAKIELKQRINVLVVPNKSLETPNYLLERLKHDDPRLDNIEPSYRLAVEAEESTAVTRGSREPTNKQVPLIKGVLPDAPAPQAPVREPAQRTAEAHGEPRDKTVVATPTIIEKGLFEWVKHLLGIFTAASQEQPAATAESPTPARAGGRRADRQRKPRNEPPQGTKAEAAFEKTDRFDKTDRADNNDKSDTPLARRSEPRQGALRTEQEAPMSPSSDGAQPPSGPRDPRDPRDPRPSRSGRSGRRTPRGGRAEGDSRTDPAQPAAPLASASLTEPVPAVDDALSAEGELGNDGASSASSADARGSRRQRDRFGRERKPRPATNADSTEAPVPPTTNDAPAQPAQAVQADAPLAPPTTLPVTAVPVAPLATAAMPAAPAIPAVPAQPYRLPEQELAQVAQESGLVWVQSDTSKVAAAQQAIAAQPEPVHVPRERPAPAPLEDSALVLVETKRDLRTVVLPFEDSAPRQ
>NC_022576.1|WP_022774299.1|1993999_1994311_+|J-domain-containing-protein
MQDHYARLGVHCNATMAEIKQAFRRQAALHHPDRNPSPDAATRFRAVQQSYEVLSDPERRKAYDDLRQRKLLDDPLPVAASLWRDYVRDLRRSFTSTTLPPSL
>NC_022576.1|WP_022774303.1|1994423_1994975_+|hypothetical-protein
MSPFFRTLHTTYQAEIDDLRQDSEGRDVLQRRLAQKRTQFAFLLQMADSNPEMAASALHGGFQFGDRAVLDRLTNLHADKLPAWSKICPTVHVAPWAQPLVAQALVAPEGERFLTIAVVLEYLYQRATHPKPNNTATQAVDEETPKQQHADADPDASDGEDIDDLDSDAGADWLASQGFDRKH
>NC_022576.1|WP_022774307.1|1994986_1995772_+|hypothetical-protein
MSYALSIVVEQTHDLIARGDIAGAESALVALADAHGDGALVEAVAQLPVRDVLAIVREFDPGKPSIVQLVLDPEQFASAVVLERNYRDPTHAHLRGMVNAVLFRDGANPLDFLDALAERDGGSEALADYFEEYWAEVIEYARTGSFEPVGELDSLPSEDEMLCHTHGTREWDGWGVESEDEGPVDSDLLHTTSGSSRLSEEEVADTDWKHLAWLLRMRRPDQFSEVLLILRAKARAFALQDAPLPDAASPGSAGLQEESAI
>NC_022576.1|WP_022774310.1|1995797_1997069_+|hypothetical-protein
MVRGTRPPLPDRRATAGSLAAYDDRLFFEKALVYGVQHGILDDARLELLAEKAAQGIVQIARYFGSEYLLAELERARERLVRFVSLALQTSSQGDLHAAAVALREQSLLALSKAGADQLKALITMPKSTHFGMNDDAAFGERHIPLLDKWSSEGWEAIQQEWAQRSQVALTLDTAMWLAGRIGVQPSVLDEAQPDAEAVIRTALLAHAAQCHETPNWPCFEAMIDTLRQSAEWTQSGQCSQCNIAATLRTVPGLPDTMQPVIDRIAHGVCDDLPRILDPHIPVRALFDQTPAFVGRYFWVDDPMGELDHHDRNASSTWYRLTQGTHDDTTLLTMLLCVAAARKPATSLSDRAAQTLVRKIRKTGWHPERATAFLDEHAPPYYRKDCQRLWNDFVQQATQTLCTADSPIRDAMALLRQECAIVG
>NC_022576.1|WP_022774318.1|1997192_1999064_+|sensor-histidine-kinase
MKTIKSQYILTGLFISLLTVLTVSVTTYFVSYSITSKLLDERMRIQVRKNASELNLWFSHYQNLIEETAEDLQITQNLDAVQLQSIFANKVRRSHGNIKDLYLGDEENNKLIIASGWVPPPDYQVRSRPWFQDAIAAHGKVIVTKPYEDAILNTDHSTDFVMTVARTVTYQDKVFVLAADISLKHVIQIVQNHSFGPNSYAFLLDQVGNVIAHPIPQFLATKKGLKNIQSIPGIDYAALIRAMTEQPYDATPVWVRDADGVRRNVMMSEITPSQWILGVATDEAEYRKPLTALLYGFVAALLLSILISMATMLRLVRRMTKPIEMLNQAVHTFASTGQNAPLELHRTDELGQLAASFNDMSATIQKRAHELEAINHKLLELDAAKSVFLSTVSHELRTPLTSVVGFAKVIRKKHDEVITPVLTNADPKIIKAITQIRGNLDIIIAESERLTLLISDVLDITRMDAGKMEWKSESVDFADVLRRAMAMTSDLFEKKGIPCTQATDPELPSVIGDGERLVQALVNLLSNAAKFTDAGQVTCEARKTPQGILVRVTDTGVGIAPELHQAIFNKFKQVGDILSSKPSGMGLGLPICKEIVEHHGGRIWVDSEPGRGSAFFMEIPTTS
>NC_022576.1|WP_022774322.1|1999121_2001056_+|SpoIIE-family-protein-phosphatase
MKKSIKTKYLLTGLVICLVSLILVSVASYYVAYSITREQTNAWVEASAMKNAVGLDWRFRKYGQILEDMASEIANHDGELQDRWLLNIIVKKNAQYSSESPTFYIVLQDNKLFYPDQNWKPLPGFDFRTRGWYLSAIKSEIPVYSTPYVDAFTGKMIITISKKLQRNGELIGVIAVDFQITDVLEIVKNYNVGESSYAFLLDQEGQFLTHPNTNFLPDQKTSLKNIYSVNIKGYSHLQARLKRGKTDIIKIVDYDNQIRYFTTAMIESNQWVLGVAIPESMYRKPLNRLFSGYIAALLLALVIGFGIMYKLVIGMTKPIKSLNDGVKSFSVENMSARVAVHSDDEIGELGKSFNQMADTIQEYSQSLEKKVADRTRELQEKNQNIMESIHYAERLQRAILPPLPHRLGIADDKCFVIWKPKDTVGGDMYWCRGDDRYVLVAVADCTGHGVPGALMTMALGSILDSLPRSLEGTKPSALLHRINLSLRETLRQENQNSLANDGADVALCLLDKQEKTFLYAGAKLSAFVEKNGQITEYKGTKHSVGYSHGREVIFEDREIKWIDGSVVYLTTDGLLDQNSVEGKGGMGRSGFIKLLQSLAGQPFAVQEQTVEQLITTSLAQVQQRDDITVVGFEMGGSLKGRIGP

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Crispr_ID: NC_022576_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022576_4

2435422-2435510

TypeI-F

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CRISPRCasFinder

1 spacers

cas3f,DinG,cas6f,cas7f,cas5f,cas8f

The CRISPR arrays of NC_022576_4

>merge|NC_022576|4|2435422-2435510|CRISPRCasFinder
TTTCTAAGCTGCCTATTCGGCAGTGAAAGTGGCTTGGCTGGCCAGTTTGTACAACTGCTTTTTCTAAGCTGCCTATTCGGCAGTGCAGG

>NC_022576|4|4|2435422-2435510|CRISPRCasFinder
TTTCTAAGCTGCCTATTCGGCAGTGAAA	GTGGCTTGGCTGGCCAGTTTGTACAACTGCTT
TTTCTAAGCTGCCTATTCGGCAGTGCAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_022576.1\|WP_022775617.1\|2444200_2444683_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350254
NC_022576.1\|WP_022775614.1\|2443298_2443742_+\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|235021
NC_022576.1\|WP_022775620.1\|2444672_2444861_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_041194600.1\|2422917_2425026_-\|ATP-dependent-DNA-helicase-DinG	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|236966
NC_022576.1\|WP_151194617.1\|2443792_2444050_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|176871
NC_022576.1\|WP_022775572.1\|2429249_2429906_-\|adenylate-kinase	unknown	unknown	gnl\|CDD\|234711
NC_022576.1\|WP_022775562.1\|2425913_2427173_+\|HD-GYP-domain-containing-protein	unknown	unknown	gnl\|CDD\|225116
NC_022576.1\|WP_022775565.1\|2427235_2427886_-\|transcriptional-repressor-LexA	unknown	unknown	gnl\|CDD\|234688
NC_022576.1\|WP_022775602.1\|2439568_2440624_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	cd09736_cas5f_CAS-I-F	gnl\|CDD\|378221
NC_022576.1\|WP_187292297.1\|2444908_2445193_-\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022775606.1\|2440613_2441909_-\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	pfam09611_cas8f_CAS-I-F	gnl\|CDD\|378220
NC_022576.1\|WP_022775575.1\|2430248_2433647_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3f	cd09673_cas3f_CAS-I-F	gnl\|CDD\|187804
NC_022576.1\|WP_022775599.1\|2438504_2439542_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	pfam09615_cas7f_CAS-I-F	gnl\|CDD\|378222
NC_022576.1\|WP_022775558.1\|2425258_2425888_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_041194602.1\|2435552_2436386_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NC_022576.1\|WP_022775552.1\|2422277_2422691_-\|biopolymer-transporter-ExbD	unknown	unknown	gnl\|CDD\|376792
NC_022576.1\|WP_041194605.1\|2437933_2438491_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	pfam09618_cas6f_CAS-I-F	gnl\|CDD\|378224
NC_022576.1\|WP_022775583.1\|2434350_2434815_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NC_022576.1\|WP_022775579.1\|2433777_2434350_-\|PIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|379205
NC_022576.1\|WP_022775569.1\|2428070_2429066_+\|asparaginase	unknown	unknown	gnl\|CDD\|214873

Protein	Function_ID	Function_description	E-value
NC_022576.1\|WP_022775617.1\|2444200_2444683_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350254	cd18687, PIN_VapC-like, uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons. Matelska et al. recently classified PIN-like domains into distinct groups; this subgroup includes some sequences belonging to one of these, PIN_3.	2.14238e-57
NC_022576.1\|WP_022775614.1\|2443298_2443742_+\|EVE-domain-containing-protein	gnl\|CDD\|235021	PRK02268, PRK02268, hypothetical protein; Provisional.	3.81597e-76
NC_022576.1\|WP_041194600.1\|2422917_2425026_-\|ATP-dependent-DNA-helicase-DinG	gnl\|CDD\|236966	PRK11747, dinG, ATP-dependent DNA helicase DinG; Provisional.	0
NC_022576.1\|WP_151194617.1\|2443792_2444050_+\|hypothetical-protein	gnl\|CDD\|176871	cd08862, SRPBCC_Smu440-like, Ligand-binding SRPBCC domain of Streptococcus mutans Smu.440 and related proteins. This family includes the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of Streptococcus mutans Smu.440 and related proteins. This domain belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. Streptococcus mutans is a dental pathogen, and the leading cause of dental caries. In this pathogen, the gene encoding Smu.440 is in the same operon as the gene encoding SMU.441, a member of the MarR protein family of transcriptional regulators involved in multiple antibiotic resistance. It has been suggested that SMU.440 is involved in polyketide-like antibiotic resistance.	8.32154e-05
NC_022576.1\|WP_022775572.1\|2429249_2429906_-\|adenylate-kinase	gnl\|CDD\|234711	PRK00279, adk, adenylate kinase; Reviewed.	5.6267e-135
NC_022576.1\|WP_022775562.1\|2425913_2427173_+\|HD-GYP-domain-containing-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	3.96446e-94
NC_022576.1\|WP_022775565.1\|2427235_2427886_-\|transcriptional-repressor-LexA	gnl\|CDD\|234688	PRK00215, PRK00215, transcriptional repressor LexA.	2.74351e-94
NC_022576.1\|WP_022775602.1\|2439568_2440624_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|378221	pfam09614, Cas_Csy2, CRISPR-associated protein (Cas_Csy2). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.	1.29451e-146
NC_022576.1\|WP_022775606.1\|2440613_2441909_-\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|378220	pfam09611, Cas_Csy1, CRISPR-associated protein (Cas_Csy1). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2465 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy1, for CRISPR/Cas Subtype Ypest protein 1.	2.07044e-176
NC_022576.1\|WP_022775575.1\|2430248_2433647_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|187804	cd09673, Cas3_Cas2_I-F, CRISPR/Cas system-associated protein Cas3/Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas3/Cas2 fusion; This protein includes both DEAH and HD motifs for helicase and N-terminal domain corresponding to Cas2 RNAse; signature gene for Type I and subtype I-F.	0
NC_022576.1\|WP_022775599.1\|2438504_2439542_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
NC_022576.1\|WP_041194602.1\|2435552_2436386_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.70965e-21
NC_022576.1\|WP_022775552.1\|2422277_2422691_-\|biopolymer-transporter-ExbD	gnl\|CDD\|376792	pfam02472, ExbD, Biopolymer transport protein ExbD/TolR. This group of proteins are membrane bound transport proteins essential for ferric ion uptake in bacteria. The Pfam family consists of ExbD, and TolR which are involved in TonB-dependent transport of various receptor bound substrates including colicins.	9.69502e-29
NC_022576.1\|WP_041194605.1\|2437933_2438491_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|378224	pfam09618, Cas_Csy4, CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	9.51357e-92
NC_022576.1\|WP_022775583.1\|2434350_2434815_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	2.17588e-12
NC_022576.1\|WP_022775579.1\|2433777_2434350_-\|PIN-domain-containing-protein	gnl\|CDD\|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	7.10551e-09
NC_022576.1\|WP_022775569.1\|2428070_2429066_+\|asparaginase	gnl\|CDD\|214873	smart00870, Asparaginase, Asparaginase, found in various plant, animal and bacterial cells. Asparaginase catalyses the deamination of asparagine to yield aspartic acid and an ammonium ion, resulting in a depletion of free circulatory asparagine in plasma. The enzyme is effective in the treatment of human malignant lymphomas, which have a diminished capacity to produce asparagine synthetase: in order to survive, such cells absorb asparagine from blood plasma..- if Asn levels have been depleted by injection of asparaginase, the lymphoma cells die.	2.89036e-101

>NC_022576.1|WP_022775583.1|2434350_2434815_-|helix-turn-helix-domain-containing-protein
MTTLSPTHSLPTAEEVAIARESGRALSAFLQTRAETQQIEIFDDRGASHPVRVPVSALRLLVDVLTEIGEGNAVSIIPIHAELTTQDAADVLNVSRPFLVQLLEHGEIPFHKIGTHRRVRYQDVIAYKERIDAERSKALHALTEQAQALKMGYE
>NC_022576.1|WP_022775579.1|2433777_2434350_-|PIN-domain-containing-protein
MSSNFTVIYDACVLYPAPLRDLLMRLALTDLYRARWTDMIHDEWMRNVLKQRPDLQAEDLERTRSLMNAHVRDSLVTGFEHLIPSVELPDTDDRHVVAAAIHGGASLIVTFNLKDFPPDQLKRYNLAAQHPDDFIFDLLDLHAARVCEAAANHRRSLKNPPKTVDEYLDTLLKQGLTQTVGQLREWKVAI
>NC_022576.1|WP_022775575.1|2430248_2433647_-|type-I-F-CRISPR-associated-helicase-Cas3
MNVLLISECDHKALTQTRRILDQFAERRGERTWQTPITRDGLDTLRRLLRQSARKNTAVACHWIRGLDHSELLWVVGDRSRFNPLGAVPTNTTERNILHANDENDWHTGEDIHLLAGLAALLHDLGKASRAFQMRLRGTLTERNQYRHEWVSLRLFEAFVGTDDDATWLARLANPTPADDASWQARLQRDGMDANVQPPFVRLAHAPLAEAIGWLVLTHHRLPTVPTGKPITTASLHQVLRQIDAGWNERTDGGDPDHRLPLYWDFAAHGLPVTTDAWRKQASKLAQRLLGLHAQPGKGQWLGNPYVMHIARLSLMLADHHYSSLGVDQRTGQPVASRVSGQTDYPLFANTHASVPEHHNGHSNPHHLNQTLDEHLVGVARHSAIVTHALPRFDTHLPHLGECKPLKKRAKDERFRWQDKAADLAASVRGRSAQHGAFIVNMASTGCGKTLANARVMYALADPAQGMRCAFAMGLRTLTLQTGRAFRDLLGLADDELAIRVGGSASRALFEHHERMAEQTGSASTQALVEEDGHVVFEGNHEAHPVLQRVLHDPHTAKLLVAPLLVCTIDHLTPATESQRGGRQIAPMLRLMSGDLVLDEPDDFDIADLPALTRLVHWAGLLGARVLLSSATLPPALVQGLFEAYRQGRVQFARNRGERPGDATPSPEVCCLWVDEYRQQHADCTDLPAYTQAHQTFARERVQRLAEAVVCRRAKFALLELGQRKCSDHPAYFAREALQWAQKLHAAHHSLDPHSGKRISFGLVRMANIEPLVDVALALYSVGVPEGQRIHLCVYHSQFPLLIRSDIEQQLDHALNRRSPDAVFSLPDIRQRIDAYPDEADHLFIVLGSPVTEVGRDHDYDWAVVEPSSMRSLIQLAGRVRRHRPDECTQPNLRVFVTNLRHFQHPGEPAFCHPGFESASHPLHSHNLIDLLRPEEYAAVDSRPRIQARDALQAATHWVDLEHARMQATMLPLPPTAPNGVAQRGRASAPPLNAASWWHLPAADALLTAALPQQQPFRQDTIPRVDLVLMPNDEGDDYALQMLLAKTGGHPGEYHILYLDRSLNKRIPDEQVQGPRIAPWGQTDYMAALTELAADMDMTLADCARRFGTVTLPQNAQGWRFHPVLGFTKQRG
>NC_022576.1|WP_022775572.1|2429249_2429906_-|adenylate-kinase
MRLILLGAPGAGKGTQATFLCQKYGIPQISTGDMLRAAVKAGTPLGLQAKQVMDAGNLVSDDLILALVRERIAQSDCESGFLFDGFPRTIAQAQALRDADVHIDIVLEIDVPFDAIVQRMSGRRAHLPSGRTYHVEFNPPKVPGIDDVTGEPLVQRDDDKEETVRKRLEVYSAQTRPLVEYYTAWAQSEPGRAPKYRAISGLGTVAEITARALAALES
>NC_022576.1|WP_022775569.1|2428070_2429066_+|asparaginase
MQKAMQNHVRNLVVLGTGGTIAGSQPDPRLAAEYDSARHGIDTLVAALPALPAGFALRTEQVANIDSKDLDFCLWAKLYERIVDHLRRAEVAGVVVTHGTDTLEETAYFLHAALPGSLTSQKPVVLTGAMRALDALGSDGPANLYDAFTLAATAGAHGVMVACAGAVHAAVEVRKTHTYRLDAFSSGDAGPLGYLENGRLRALRPWPAAPATQPREALDRAIRANAWPRVEIVMGYAGGSAAVIDALLRNSGGDTPPLRGIVVAATGNGTLHHAMEAALRRACDAGVRVVLTSRCGPIVPHAGMAFSHADSLTAVQARVAMMLDCMAHDAR
>NC_022576.1|WP_022775565.1|2427235_2427886_-|transcriptional-repressor-LexA
MSSSPTLTPCQRRVLDFLQDTIVRTGVPPTRAEVATALGFRSANAAQEHLQALARKGVIELGQGSARGIRIPGHCPGHFPADEPMGAVWTLPLVGRVAAGLPILAQEHLEGSYPVAAGLFAQRPDYLLRVQGTSMLGAGILDGDLLAIHACPEAQTGQIVVARIGEEVTVKRLVRTDRMIELHPENPQYPVLTVTAEQPFAIEGIVVGLIRPAVRK
>NC_022576.1|WP_022775562.1|2425913_2427173_+|HD-GYP-domain-containing-protein
MLKRIGVQQLVLGMHVKEFCGSWMEHPFWRTGFVLTDPKDLEAIRSSSIREVWIDAALGLDVAQGESAVTEEEANAEVTQALDSASSPLEPVSIPRRNQTPTPRAKEVERAARICIESKTAVQSMFEEVRLGNAVDSESANALVEEISDSITRNPGAIISLARLKTADDYTYMHSVAVCAMMVALARQLDLGAETTRSCGLAGLLHDMGKVAVPKSILNKPGKLTEEEFEKMKAHPGEGHDILLRSEGMDPIALDVVWHHHEKVDGSGYPKRLRDEEITLFSKMGAVCDVYDAITSNRPYKNGWDPAESMRKMAEWTRTHFDQRIFQYFVKSMGIYPVGSLVRLASGRIGVVVEQSSGTLTAPIVKVFYSTKSGLRFEPALIDLSHPKTTDKIVQREDPTQWNFHDLDVLWSGLPNYRP
>NC_022576.1|WP_022775558.1|2425258_2425888_+|hypothetical-protein
MPHYESPLEIHVHGQVALRRDVGPAHLEEALQPLWRYTGSPSLWAAAQSCYEDEPGIAFIADQHLLQMCWTVVGAENFRQALDEMCMNLNDLSIDGAVLEVTFYDTRYDEEDDEEDEEEPPTRDDFFLLFIGPDPGSIMQVQRDLLVQDVVELMERHFDRTELEGIVQQIDLLFQQRLSSLVNSLQLGKPPRGGGAPPHAGGRKPRKAR
>NC_022576.1|WP_041194600.1|2422917_2425026_-|ATP-dependent-DNA-helicase-DinG
MDANAAARAMEAFDRLMASNPAFCQRPGQRAMAQRIADSLHDATPGNARRAIAVIQAGTGVGKSAAYLATAVGLALSCNTRVVVSTATVALQEQLLHKDLPALAAALDVPLTFALAKGRGRYVCKLQLERYADAEGGSLLDWAEDGTPQSEGEPRSRSQTAQFERRMRLYRSLAQALAEGEWAGDRDTLSQPMDPADWAPIAAERHTCTARHCPRYRDCCYYSAKLALVQAQVIVANHDLILASLGMRALPDPDKCILVFDEGHHLPSVALERFASAMDVTNLRWLDRLPGVLHSAAREMEHTPSIDVSATALQLRRAMQDIARALQGLVPIATTADSATHRFPNGVWPQELVEPMALTQEHACTLLHELTELGAALKRQARDNPTQSADCAARYANLGQMASRLSGVAQAASMLLAPEERSVAKWVEASAPSGIVTLRIHAGPLFAGGLLQERLWNVAQAVVITSATLTTCNSFDYFLRETGLQGLPQVSALAVDSPFDYARQGELVVVATAADPRNVEAYTQEVVQALLADLREVERGALALFTSRTQMQAAVNALDEALRERVLVQGDMARPRLLERHAERIAAGQPSILFGLQSFGEGLDLPGPLCEVLYIAKLPFAPPTDPVQEARAEWLRSRGGDPFHELVVPETGIRLLQWTGRAIRTETDRARLVCYDKRLTHTAYGRRILAGLPPYAKVQRNC
>NC_022576.1|WP_022775552.1|2422277_2422691_-|biopolymer-transporter-ExbD
MHFRPRPLEEPEINLIPFIDVLLVILIFLMLSTTYSKFTELRIELPVADADAQRNQPREIVVGVGSEGQYSVNQVPVGSRTVPELVEALRAAGGDSSTVLVIAADAAAKHQSVVHVMEAARGAGLSHITFATQSAGR
>NC_022576.1|WP_041194602.1|2435552_2436386_-|IS5-family-transposase
MGLIFHDDGWRLHDALWGIIKSSLPEPKKHPLGCHNPRVSDRSAMNAILFVLRTGCQWNALNMTGICSCSSAYRRFREWTKAGVFSALWIQQLVEYDKSQGIDWAWTSMDGALTKAPLAGQQTTGANPTDRGKQGVKRSVLTDGAGIPLAVAIDGANRHDMKLVRSTLEDIKAKRPDPTDTKPQGICLDKGYDYDEVREIVKEFGFTAHIRSRGEEAKSIKQEAGFKARRWVVERTHSWMNRFRRILVRWEKLPETYIAMLHITCALITLRAYCLPK
>NC_022576.1|WP_041194605.1|2437933_2438491_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MSHYVNMDVRPDGDFPSSQLMGALYVRLHRALVAHGAGDIGVCFPAHNEHWLGNRMRLHGSAEALGKLMGVDWLQGMRDHLDLTPVSPVPDQMGYRQVKRVQPQSSPERLRRRLMLRHKLTAEEAAERIPDTVAQLVALPSVFVRSSSTGQSFRLFVCHGPLTPEPKEGGFSTYGLSLGGAVPWF
>NC_022576.1|WP_022775599.1|2438504_2439542_-|type-I-F-CRISPR-associated-protein-Csy3
MATTNPLKTASVLAFDRKLDPSDALFAAGTWAHRANSAAWPPVAVRAKSVRGTISNRLKTKDQDPAKLDAAIENPNLQTVDVATLPAEADTLQVSFTLRVLGGTGTPSACNNADYQRVLVDTVNGYVATHGFAELARRYAANLANGRFLWRNRLGAEQIEVQVARLVDGRAANTWTFDALAHSLRGFDAPETMHPDLGAVSTLLAQGLAGKSHVLLQVTAFVRMGSGQEVYPSQELILDKDKANKSKTLYTVNGIAGMHSQKLGNAIRTIDTWYTGAADNGPIAVEPYGSVTTQGKAYRQPKQKEDFYTLLDNWVTKGQAPALEQQHFVVATLIRGGVFGDTDKG
>NC_022576.1|WP_022775602.1|2439568_2440624_-|type-I-F-CRISPR-associated-protein-Csy2
MPTDAPQHAALLVLPRLRVQNANAISSPMTWGFPAITAFSGFMAALARRLVPDAGIQFHGVGVVCHHFEAQVTQGGYVRNFHLTRNPVLADGSTAAIVEEGHIHLDITLVFDVSLAHHLQDDTTRTSLAAHVGEVVAGMRLAGGSIMPPLPGTLRRAPRAQLKLLHDETDARRAQEFRHLSRRWLPGFALVSADEVLQRTHQDALQAQAPNGTPPPTLFDTWLDLSRINHRPVKKTVWDEAIGDYQNTVTWETDKRPGWLVPIPVGFAALSALHPPGAVAGARDAATPFRFVECVYSMGQWISPHRLRDTQQMMWYAEHDAESGLYRCTNGYQVPPQSQAPLSVTPPVHQD
>NC_022576.1|WP_022775606.1|2440613_2441909_-|type-I-F-CRISPR-associated-protein-Csy1
MLTPRQAALRLLITDFLSQRLESKLEKLPPDDPKRADLQRDFAPAAWLEDAARRAAQIQVVTHSLKPIHPEAKGTNLYCPPDALAPVPVVGSHCLTDDFAGDVVGNAAALDVYKFLKQEHEGQTLLALAVSGDVDWAQALSDDPAQAQAWMSAFASLATPHGNPTSHTLAKQLYWPVGDDLHDDAGYHLLAPLYASSLAHRLYQTLQDDRFSDEAKAAREARKADLVSERPVRDYPNLAVQQLGGTKPQNISQLNSERRGQNSLLASLPPMWRSVELKPLWGTESMFPRYKSRPAVKENLGALLAFLKTDPKRNVDTRDRRAAYVDNLIDDFLQFTAEVRTLEPGWSCNNKCRLPAEQAYWLDPEGAAQADAELGRPPPTDTHERICEAYANWLNAQLRDPLPMGDPEFEAWRKAMQEHILAEEREGLHAD
>NC_022576.1|WP_022775614.1|2443298_2443742_+|EVE-domain-containing-protein
MRYWIGVASKEHVNRGVSGGFCQLCHGKAQPLKRMSVGDWIIYYSPKELFEEATPCQKFTAIGEVVGSEVYPFEMFPGFVPHRRDIHFLKASDVPIRPLLEQLSFIQDKRKWGYAFRYGHLEIPISDFELIATKMLGHVPANIHEEK
>NC_022576.1|WP_151194617.1|2443792_2444050_+|hypothetical-protein
MFRAIADINSWSKWDKGLEFTKIEGVARPGVLFVLKPKGGPNVQITIDEIKPYRLVNTAHLFLAKMRTSHDVCPIWRPNNYPIFC
>NC_022576.1|WP_022775617.1|2444200_2444683_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MKRKVYIETSVISYLTARPSKSILGTAHQQITLAWWETRSQYDLVVSELVLRECGAGDPDAAKKRLTMLNDVPLILITEQALDIANSLIAKGIVPAKAAEDALHIAISTSNRIDYLLTWNCWHIANPEMQRGISAHLDDIGLSLPFICTPEELLGEEDVE
>NC_022576.1|WP_022775620.1|2444672_2444861_+|hypothetical-protein
MWNDEILDEVRAIRDAHAAKFGYDLQAIYADLKKSEAEHIAAGHPFIPAPERPVPNRVGNGF
>NC_022576.1|WP_187292297.1|2444908_2445193_-|hypothetical-protein
MDQKAHPNVLLETVALAAHEDQELTGIGHKPEIGDSARSQQQQLLADVQNPGYQSGHIQRVVTGAGFAECERPVVQSTGIHGYETKDFVERAGL

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Crispr_ID: NC_022576_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022576_5

2436455-2437804

TypeI-F

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CRISPRCasFinder
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CRT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	PILER-CR

22 spacers

cas3f,DinG,cas6f,cas7f,cas5f,cas8f

The CRISPR arrays of NC_022576_5

>merge|NC_022576|5|2436455-2437804|CRISPRCasFinder,CRT,PILER-CR
GCTCTAAGCTGCCTATTCGGCAGTGAAGTCGATCACGCCCTCGGCGGATTGCTCTGGTGTTTTCTAAGCTGCCTATTCGGCAGTGAAGTTTTTGGAAGCCGCATAGTCGCGGCACTTTTTTTTCTAAGCTGCCTATTCGGCAGTGAAGTTGTTTGAGCCTGCCATCACGCCATGCGGACATTTCTAAGCTGCCTATTCGGCAGTGAAGGACTTCCCCGCGTGCGCGACGGAGGATCCAACAGTTTCTAAGCTGCCTATTCGGCAGTGAAGTCTGCTACGTGCAGTGCGTCATCCCCTCTAGCTTTCTAAGCTGCCTATTCGGCAGTGAAGTTCTCATCGCGTGCGCAGGGCTGCTGCTATGGTTTCTAAGCTGCCTATTCGGCAGTGAAGCCGGAATGGACGGTTCGCGGCCTCACTTCAGCTTTCTAAGCTGCCTATTCGGCAGTGAAGCGGTAGTGTTCGAGATTGACGTTTGGGCGGTTTTTCTAAGCTGCCTATTCGGCAGTGAAGCGCATGGTAGTCCCAGACGAGCTAGAGATCGATTTCTAAGCTGCCTATTCGGCAGTGAAGGATGACTCCGACCTCCCAATCACGATCGTTCATTTCTAAGCTGCCTATTCGGCAGTGAAGGTCTGCAATGCCGATTCGGTATCCTGGGAATATTTCTAAGCTGCCTATTCGGCAGTGAAGGCATCCTCGGCGTTAGCCGCACGTTCCCGGCTTTTCTAAGCTGCCTATTCGGCAGTGAAGCAGTACGAGCGTGCTTTGTTGTGCGCCTGGGCTTTCTAAGCTACCTATTCGGCAGTGAAGGAAGTAGATAGATATCCATGGGAGGTTGGCCATTTCTAAGCTGCCTATTCGGCAGTGAAGGCGCGCTTCAAACAGGAACCGGTTACGCTCTTTTTCTAAGCTGCCTATTCGGCAGTGAAGTGGCGCGGGTAGGGGCGCTGCGTAGTTTGCTGTTTCTAAGCTGCCTATTCGGCAGTGAAGTTTATGGCGCGGACTCCGCATCTCGGCTTGTTTTTCTAAGCTGCCTATTCGGCAGTGAAGTCGATGCCAATTCAGTATGTGATTTGTGATGATTTCTAAGCTGCCTATTCGGCAGTGAAGAATTCTGGCCATTGTGTGTTGTTTTTGCAAATTTTCTAAGCTGCCTATTCGGCAGTGAAGTGACTCGTCGCGCCTATCTTTTTGCTTTTTCATTTCTAAGCTGCCTATTCGGCAGTGAAGATTGACATGCCAGCCGTAACGCTTGCTGAATTTTTCTAAGCTGCCTATTCGGCAGTGAAGGGATGTTGTTACCTTCCACGGCCTTGCCCGTTTTTCTAAGCTGCCTATTCGGCAGTGAAG

>NC_022576|5|5|2436455-2437804|CRISPRCasFinder
GCTCTAAGCTGCCTATTCGGCAGTGAAG	TCGATCACGCCCTCGGCGGATTGCTCTGGTGT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TTTTTGGAAGCCGCATAGTCGCGGCACTTTTT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TTGTTTGAGCCTGCCATCACGCCATGCGGACA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GACTTCCCCGCGTGCGCGACGGAGGATCCAACAG
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TCTGCTACGTGCAGTGCGTCATCCCCTCTAGC
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TTCTCATCGCGTGCGCAGGGCTGCTGCTATGG
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CCGGAATGGACGGTTCGCGGCCTCACTTCAGC
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CGGTAGTGTTCGAGATTGACGTTTGGGCGGTT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CGCATGGTAGTCCCAGACGAGCTAGAGATCGA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GATGACTCCGACCTCCCAATCACGATCGTTCA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GTCTGCAATGCCGATTCGGTATCCTGGGAATA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GCATCCTCGGCGTTAGCCGCACGTTCCCGGCT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CAGTACGAGCGTGCTTTGTTGTGCGCCTGGGC
TTTCTAAGCTACCTATTCGGCAGTGAAG	GAAGTAGATAGATATCCATGGGAGGTTGGCCA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GCGCGCTTCAAACAGGAACCGGTTACGCTCTT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TGGCGCGGGTAGGGGCGCTGCGTAGTTTGCTG
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TTTATGGCGCGGACTCCGCATCTCGGCTTGTT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TCGATGCCAATTCAGTATGTGATTTGTGATGA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	AATTCTGGCCATTGTGTGTTGTTTTTGCAAAT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TGACTCGTCGCGCCTATCTTTTTGCTTTTTCA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	ATTGACATGCCAGCCGTAACGCTTGCTGAATT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GGATGTTGTTACCTTCCACGGCCTTGCCCGTT
TTTCTAAGCTGCCTATTCGGCAGTGAAG

>NC_022576|5|3|2436455-2437804|CRT
GCTCTAAGCTGCCTATTCGGCAGTGAAG	TCGATCACGCCCTCGGCGGATTGCTCTGGTGT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TTTTTGGAAGCCGCATAGTCGCGGCACTTTTT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TTGTTTGAGCCTGCCATCACGCCATGCGGACA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GACTTCCCCGCGTGCGCGACGGAGGATCCAACAG
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TCTGCTACGTGCAGTGCGTCATCCCCTCTAGC
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TTCTCATCGCGTGCGCAGGGCTGCTGCTATGG
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CCGGAATGGACGGTTCGCGGCCTCACTTCAGC
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CGGTAGTGTTCGAGATTGACGTTTGGGCGGTT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CGCATGGTAGTCCCAGACGAGCTAGAGATCGA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GATGACTCCGACCTCCCAATCACGATCGTTCA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GTCTGCAATGCCGATTCGGTATCCTGGGAATA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GCATCCTCGGCGTTAGCCGCACGTTCCCGGCT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	CAGTACGAGCGTGCTTTGTTGTGCGCCTGGGC
TTTCTAAGCTACCTATTCGGCAGTGAAG	GAAGTAGATAGATATCCATGGGAGGTTGGCCA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GCGCGCTTCAAACAGGAACCGGTTACGCTCTT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TGGCGCGGGTAGGGGCGCTGCGTAGTTTGCTG
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TTTATGGCGCGGACTCCGCATCTCGGCTTGTT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TCGATGCCAATTCAGTATGTGATTTGTGATGA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	AATTCTGGCCATTGTGTGTTGTTTTTGCAAAT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	TGACTCGTCGCGCCTATCTTTTTGCTTTTTCA
TTTCTAAGCTGCCTATTCGGCAGTGAAG	ATTGACATGCCAGCCGTAACGCTTGCTGAATT
TTTCTAAGCTGCCTATTCGGCAGTGAAG	GGATGTTGTTACCTTCCACGGCCTTGCCCGTT
TTTCTAAGCTGCCTATTCGGCAGTGAAG

>NC_022576|5|3|2436457-2437804|PILER-CR
TCTAAGCTGCCTATTCGGCAGTGAAGTC	GATCACGCCCTCGGCGGATTGCTCTGGTGTTT
TCTAAGCTGCCTATTCGGCAGTGAAGTT	TTTGGAAGCCGCATAGTCGCGGCACTTTTTTT
TCTAAGCTGCCTATTCGGCAGTGAAGTT	GTTTGAGCCTGCCATCACGCCATGCGGACATT
TCTAAGCTGCCTATTCGGCAGTGAAGGA	CTTCCCCGCGTGCGCGACGGAGGATCCAACAGTT
TCTAAGCTGCCTATTCGGCAGTGAAGTC	TGCTACGTGCAGTGCGTCATCCCCTCTAGCTT
TCTAAGCTGCCTATTCGGCAGTGAAGTT	CTCATCGCGTGCGCAGGGCTGCTGCTATGGTT
TCTAAGCTGCCTATTCGGCAGTGAAGCC	GGAATGGACGGTTCGCGGCCTCACTTCAGCTT
TCTAAGCTGCCTATTCGGCAGTGAAGCG	GTAGTGTTCGAGATTGACGTTTGGGCGGTTTT
TCTAAGCTGCCTATTCGGCAGTGAAGCG	CATGGTAGTCCCAGACGAGCTAGAGATCGATT
TCTAAGCTGCCTATTCGGCAGTGAAGGA	TGACTCCGACCTCCCAATCACGATCGTTCATT
TCTAAGCTGCCTATTCGGCAGTGAAGGT	CTGCAATGCCGATTCGGTATCCTGGGAATATT
TCTAAGCTGCCTATTCGGCAGTGAAGGC	ATCCTCGGCGTTAGCCGCACGTTCCCGGCTTT
TCTAAGCTGCCTATTCGGCAGTGAAGCA	GTACGAGCGTGCTTTGTTGTGCGCCTGGGCTT
TCTAAGCTACCTATTCGGCAGTGAAGGA	AGTAGATAGATATCCATGGGAGGTTGGCCATT
TCTAAGCTGCCTATTCGGCAGTGAAGGC	GCGCTTCAAACAGGAACCGGTTACGCTCTTTT
TCTAAGCTGCCTATTCGGCAGTGAAGTG	GCGCGGGTAGGGGCGCTGCGTAGTTTGCTGTT
TCTAAGCTGCCTATTCGGCAGTGAAGTT	TATGGCGCGGACTCCGCATCTCGGCTTGTTTT
TCTAAGCTGCCTATTCGGCAGTGAAGTC	GATGCCAATTCAGTATGTGATTTGTGATGATT
TCTAAGCTGCCTATTCGGCAGTGAAGAA	TTCTGGCCATTGTGTGTTGTTTTTGCAAATTT
TCTAAGCTGCCTATTCGGCAGTGAAGTG	ACTCGTCGCGCCTATCTTTTTGCTTTTTCATT
TCTAAGCTGCCTATTCGGCAGTGAAGAT	TGACATGCCAGCCGTAACGCTTGCTGAATTTT
TCTAAGCTGCCTATTCGGCAGTGAAGGG	ATGTTGTTACCTTCCACGGCCTTGCCCGTTTT
TCTAAGCTGCCTATTCGGCAGTGAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_022576.1\|WP_022775617.1\|2444200_2444683_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350254
NC_022576.1\|WP_022775614.1\|2443298_2443742_+\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|235021
NC_022576.1\|WP_022775620.1\|2444672_2444861_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_041194600.1\|2422917_2425026_-\|ATP-dependent-DNA-helicase-DinG	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|236966
NC_022576.1\|WP_151194617.1\|2443792_2444050_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|176871
NC_022576.1\|WP_022775572.1\|2429249_2429906_-\|adenylate-kinase	unknown	unknown	gnl\|CDD\|234711
NC_022576.1\|WP_022775630.1\|2445853_2446126_+\|DUF2442-domain-containing-protein	unknown	unknown	gnl\|CDD\|378424
NC_022576.1\|WP_022775562.1\|2425913_2427173_+\|HD-GYP-domain-containing-protein	unknown	unknown	gnl\|CDD\|225116
NC_022576.1\|WP_022775565.1\|2427235_2427886_-\|transcriptional-repressor-LexA	unknown	unknown	gnl\|CDD\|234688
NC_022576.1\|WP_022775602.1\|2439568_2440624_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	cd09736_cas5f_CAS-I-F	gnl\|CDD\|378221
NC_022576.1\|WP_187292297.1\|2444908_2445193_-\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_022775606.1\|2440613_2441909_-\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	pfam09611_cas8f_CAS-I-F	gnl\|CDD\|378220
NC_022576.1\|WP_022775575.1\|2430248_2433647_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3f	cd09673_cas3f_CAS-I-F	gnl\|CDD\|187804
NC_022576.1\|WP_022775599.1\|2438504_2439542_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	pfam09615_cas7f_CAS-I-F	gnl\|CDD\|378222
NC_022576.1\|WP_022775558.1\|2425258_2425888_+\|hypothetical-protein	unknown	unknown	unknown
NC_022576.1\|WP_041194602.1\|2435552_2436386_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NC_022576.1\|WP_041194605.1\|2437933_2438491_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	pfam09618_cas6f_CAS-I-F	gnl\|CDD\|378224
NC_022576.1\|WP_022775583.1\|2434350_2434815_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NC_022576.1\|WP_022775579.1\|2433777_2434350_-\|PIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|379205
NC_022576.1\|WP_022775569.1\|2428070_2429066_+\|asparaginase	unknown	unknown	gnl\|CDD\|214873

Protein	Function_ID	Function_description	E-value
NC_022576.1\|WP_022775617.1\|2444200_2444683_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350254	cd18687, PIN_VapC-like, uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons. Matelska et al. recently classified PIN-like domains into distinct groups; this subgroup includes some sequences belonging to one of these, PIN_3.	2.14238e-57
NC_022576.1\|WP_022775614.1\|2443298_2443742_+\|EVE-domain-containing-protein	gnl\|CDD\|235021	PRK02268, PRK02268, hypothetical protein; Provisional.	3.81597e-76
NC_022576.1\|WP_041194600.1\|2422917_2425026_-\|ATP-dependent-DNA-helicase-DinG	gnl\|CDD\|236966	PRK11747, dinG, ATP-dependent DNA helicase DinG; Provisional.	0
NC_022576.1\|WP_151194617.1\|2443792_2444050_+\|hypothetical-protein	gnl\|CDD\|176871	cd08862, SRPBCC_Smu440-like, Ligand-binding SRPBCC domain of Streptococcus mutans Smu.440 and related proteins. This family includes the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of Streptococcus mutans Smu.440 and related proteins. This domain belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. Streptococcus mutans is a dental pathogen, and the leading cause of dental caries. In this pathogen, the gene encoding Smu.440 is in the same operon as the gene encoding SMU.441, a member of the MarR protein family of transcriptional regulators involved in multiple antibiotic resistance. It has been suggested that SMU.440 is involved in polyketide-like antibiotic resistance.	8.32154e-05
NC_022576.1\|WP_022775572.1\|2429249_2429906_-\|adenylate-kinase	gnl\|CDD\|234711	PRK00279, adk, adenylate kinase; Reviewed.	5.6267e-135
NC_022576.1\|WP_022775562.1\|2425913_2427173_+\|HD-GYP-domain-containing-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	3.96446e-94
NC_022576.1\|WP_022775565.1\|2427235_2427886_-\|transcriptional-repressor-LexA	gnl\|CDD\|234688	PRK00215, PRK00215, transcriptional repressor LexA.	2.74351e-94
NC_022576.1\|WP_022775602.1\|2439568_2440624_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|378221	pfam09614, Cas_Csy2, CRISPR-associated protein (Cas_Csy2). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.	1.29451e-146
NC_022576.1\|WP_022775606.1\|2440613_2441909_-\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|378220	pfam09611, Cas_Csy1, CRISPR-associated protein (Cas_Csy1). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2465 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy1, for CRISPR/Cas Subtype Ypest protein 1.	2.07044e-176
NC_022576.1\|WP_022775575.1\|2430248_2433647_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|187804	cd09673, Cas3_Cas2_I-F, CRISPR/Cas system-associated protein Cas3/Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas3/Cas2 fusion; This protein includes both DEAH and HD motifs for helicase and N-terminal domain corresponding to Cas2 RNAse; signature gene for Type I and subtype I-F.	0
NC_022576.1\|WP_022775599.1\|2438504_2439542_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
NC_022576.1\|WP_022775630.1\|2445853_2446126_+\|DUF2442-domain-containing-protein	gnl\|CDD\|378424	pfam10387, DUF2442, Protein of unknown function (DUF2442). This family of bacterial and fungal proteins has several members annotated as being putative molybdopterin-guanine dinucleotide biosynthesis protein A; however this could not be verified. Hence the function is not known. This family also includes the DUF3532 that was found to be related and was merged into this family. Members of this family also fall into the NE0471 N-terminal domain-like superfamily, a family of proteins with a unique fold in SCOP:143880.	2.36491e-08
NC_022576.1\|WP_041194602.1\|2435552_2436386_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.70965e-21
NC_022576.1\|WP_041194605.1\|2437933_2438491_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|378224	pfam09618, Cas_Csy4, CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	9.51357e-92
NC_022576.1\|WP_022775583.1\|2434350_2434815_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	2.17588e-12
NC_022576.1\|WP_022775579.1\|2433777_2434350_-\|PIN-domain-containing-protein	gnl\|CDD\|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	7.10551e-09
NC_022576.1\|WP_022775569.1\|2428070_2429066_+\|asparaginase	gnl\|CDD\|214873	smart00870, Asparaginase, Asparaginase, found in various plant, animal and bacterial cells. Asparaginase catalyses the deamination of asparagine to yield aspartic acid and an ammonium ion, resulting in a depletion of free circulatory asparagine in plasma. The enzyme is effective in the treatment of human malignant lymphomas, which have a diminished capacity to produce asparagine synthetase: in order to survive, such cells absorb asparagine from blood plasma..- if Asn levels have been depleted by injection of asparaginase, the lymphoma cells die.	2.89036e-101

>NC_022576.1|WP_041194602.1|2435552_2436386_-|IS5-family-transposase
MGLIFHDDGWRLHDALWGIIKSSLPEPKKHPLGCHNPRVSDRSAMNAILFVLRTGCQWNALNMTGICSCSSAYRRFREWTKAGVFSALWIQQLVEYDKSQGIDWAWTSMDGALTKAPLAGQQTTGANPTDRGKQGVKRSVLTDGAGIPLAVAIDGANRHDMKLVRSTLEDIKAKRPDPTDTKPQGICLDKGYDYDEVREIVKEFGFTAHIRSRGEEAKSIKQEAGFKARRWVVERTHSWMNRFRRILVRWEKLPETYIAMLHITCALITLRAYCLPK
>NC_022576.1|WP_022775583.1|2434350_2434815_-|helix-turn-helix-domain-containing-protein
MTTLSPTHSLPTAEEVAIARESGRALSAFLQTRAETQQIEIFDDRGASHPVRVPVSALRLLVDVLTEIGEGNAVSIIPIHAELTTQDAADVLNVSRPFLVQLLEHGEIPFHKIGTHRRVRYQDVIAYKERIDAERSKALHALTEQAQALKMGYE
>NC_022576.1|WP_022775579.1|2433777_2434350_-|PIN-domain-containing-protein
MSSNFTVIYDACVLYPAPLRDLLMRLALTDLYRARWTDMIHDEWMRNVLKQRPDLQAEDLERTRSLMNAHVRDSLVTGFEHLIPSVELPDTDDRHVVAAAIHGGASLIVTFNLKDFPPDQLKRYNLAAQHPDDFIFDLLDLHAARVCEAAANHRRSLKNPPKTVDEYLDTLLKQGLTQTVGQLREWKVAI
>NC_022576.1|WP_022775575.1|2430248_2433647_-|type-I-F-CRISPR-associated-helicase-Cas3
MNVLLISECDHKALTQTRRILDQFAERRGERTWQTPITRDGLDTLRRLLRQSARKNTAVACHWIRGLDHSELLWVVGDRSRFNPLGAVPTNTTERNILHANDENDWHTGEDIHLLAGLAALLHDLGKASRAFQMRLRGTLTERNQYRHEWVSLRLFEAFVGTDDDATWLARLANPTPADDASWQARLQRDGMDANVQPPFVRLAHAPLAEAIGWLVLTHHRLPTVPTGKPITTASLHQVLRQIDAGWNERTDGGDPDHRLPLYWDFAAHGLPVTTDAWRKQASKLAQRLLGLHAQPGKGQWLGNPYVMHIARLSLMLADHHYSSLGVDQRTGQPVASRVSGQTDYPLFANTHASVPEHHNGHSNPHHLNQTLDEHLVGVARHSAIVTHALPRFDTHLPHLGECKPLKKRAKDERFRWQDKAADLAASVRGRSAQHGAFIVNMASTGCGKTLANARVMYALADPAQGMRCAFAMGLRTLTLQTGRAFRDLLGLADDELAIRVGGSASRALFEHHERMAEQTGSASTQALVEEDGHVVFEGNHEAHPVLQRVLHDPHTAKLLVAPLLVCTIDHLTPATESQRGGRQIAPMLRLMSGDLVLDEPDDFDIADLPALTRLVHWAGLLGARVLLSSATLPPALVQGLFEAYRQGRVQFARNRGERPGDATPSPEVCCLWVDEYRQQHADCTDLPAYTQAHQTFARERVQRLAEAVVCRRAKFALLELGQRKCSDHPAYFAREALQWAQKLHAAHHSLDPHSGKRISFGLVRMANIEPLVDVALALYSVGVPEGQRIHLCVYHSQFPLLIRSDIEQQLDHALNRRSPDAVFSLPDIRQRIDAYPDEADHLFIVLGSPVTEVGRDHDYDWAVVEPSSMRSLIQLAGRVRRHRPDECTQPNLRVFVTNLRHFQHPGEPAFCHPGFESASHPLHSHNLIDLLRPEEYAAVDSRPRIQARDALQAATHWVDLEHARMQATMLPLPPTAPNGVAQRGRASAPPLNAASWWHLPAADALLTAALPQQQPFRQDTIPRVDLVLMPNDEGDDYALQMLLAKTGGHPGEYHILYLDRSLNKRIPDEQVQGPRIAPWGQTDYMAALTELAADMDMTLADCARRFGTVTLPQNAQGWRFHPVLGFTKQRG
>NC_022576.1|WP_022775572.1|2429249_2429906_-|adenylate-kinase
MRLILLGAPGAGKGTQATFLCQKYGIPQISTGDMLRAAVKAGTPLGLQAKQVMDAGNLVSDDLILALVRERIAQSDCESGFLFDGFPRTIAQAQALRDADVHIDIVLEIDVPFDAIVQRMSGRRAHLPSGRTYHVEFNPPKVPGIDDVTGEPLVQRDDDKEETVRKRLEVYSAQTRPLVEYYTAWAQSEPGRAPKYRAISGLGTVAEITARALAALES
>NC_022576.1|WP_022775569.1|2428070_2429066_+|asparaginase
MQKAMQNHVRNLVVLGTGGTIAGSQPDPRLAAEYDSARHGIDTLVAALPALPAGFALRTEQVANIDSKDLDFCLWAKLYERIVDHLRRAEVAGVVVTHGTDTLEETAYFLHAALPGSLTSQKPVVLTGAMRALDALGSDGPANLYDAFTLAATAGAHGVMVACAGAVHAAVEVRKTHTYRLDAFSSGDAGPLGYLENGRLRALRPWPAAPATQPREALDRAIRANAWPRVEIVMGYAGGSAAVIDALLRNSGGDTPPLRGIVVAATGNGTLHHAMEAALRRACDAGVRVVLTSRCGPIVPHAGMAFSHADSLTAVQARVAMMLDCMAHDAR
>NC_022576.1|WP_022775565.1|2427235_2427886_-|transcriptional-repressor-LexA
MSSSPTLTPCQRRVLDFLQDTIVRTGVPPTRAEVATALGFRSANAAQEHLQALARKGVIELGQGSARGIRIPGHCPGHFPADEPMGAVWTLPLVGRVAAGLPILAQEHLEGSYPVAAGLFAQRPDYLLRVQGTSMLGAGILDGDLLAIHACPEAQTGQIVVARIGEEVTVKRLVRTDRMIELHPENPQYPVLTVTAEQPFAIEGIVVGLIRPAVRK
>NC_022576.1|WP_022775562.1|2425913_2427173_+|HD-GYP-domain-containing-protein
MLKRIGVQQLVLGMHVKEFCGSWMEHPFWRTGFVLTDPKDLEAIRSSSIREVWIDAALGLDVAQGESAVTEEEANAEVTQALDSASSPLEPVSIPRRNQTPTPRAKEVERAARICIESKTAVQSMFEEVRLGNAVDSESANALVEEISDSITRNPGAIISLARLKTADDYTYMHSVAVCAMMVALARQLDLGAETTRSCGLAGLLHDMGKVAVPKSILNKPGKLTEEEFEKMKAHPGEGHDILLRSEGMDPIALDVVWHHHEKVDGSGYPKRLRDEEITLFSKMGAVCDVYDAITSNRPYKNGWDPAESMRKMAEWTRTHFDQRIFQYFVKSMGIYPVGSLVRLASGRIGVVVEQSSGTLTAPIVKVFYSTKSGLRFEPALIDLSHPKTTDKIVQREDPTQWNFHDLDVLWSGLPNYRP
>NC_022576.1|WP_022775558.1|2425258_2425888_+|hypothetical-protein
MPHYESPLEIHVHGQVALRRDVGPAHLEEALQPLWRYTGSPSLWAAAQSCYEDEPGIAFIADQHLLQMCWTVVGAENFRQALDEMCMNLNDLSIDGAVLEVTFYDTRYDEEDDEEDEEEPPTRDDFFLLFIGPDPGSIMQVQRDLLVQDVVELMERHFDRTELEGIVQQIDLLFQQRLSSLVNSLQLGKPPRGGGAPPHAGGRKPRKAR
>NC_022576.1|WP_041194600.1|2422917_2425026_-|ATP-dependent-DNA-helicase-DinG
MDANAAARAMEAFDRLMASNPAFCQRPGQRAMAQRIADSLHDATPGNARRAIAVIQAGTGVGKSAAYLATAVGLALSCNTRVVVSTATVALQEQLLHKDLPALAAALDVPLTFALAKGRGRYVCKLQLERYADAEGGSLLDWAEDGTPQSEGEPRSRSQTAQFERRMRLYRSLAQALAEGEWAGDRDTLSQPMDPADWAPIAAERHTCTARHCPRYRDCCYYSAKLALVQAQVIVANHDLILASLGMRALPDPDKCILVFDEGHHLPSVALERFASAMDVTNLRWLDRLPGVLHSAAREMEHTPSIDVSATALQLRRAMQDIARALQGLVPIATTADSATHRFPNGVWPQELVEPMALTQEHACTLLHELTELGAALKRQARDNPTQSADCAARYANLGQMASRLSGVAQAASMLLAPEERSVAKWVEASAPSGIVTLRIHAGPLFAGGLLQERLWNVAQAVVITSATLTTCNSFDYFLRETGLQGLPQVSALAVDSPFDYARQGELVVVATAADPRNVEAYTQEVVQALLADLREVERGALALFTSRTQMQAAVNALDEALRERVLVQGDMARPRLLERHAERIAAGQPSILFGLQSFGEGLDLPGPLCEVLYIAKLPFAPPTDPVQEARAEWLRSRGGDPFHELVVPETGIRLLQWTGRAIRTETDRARLVCYDKRLTHTAYGRRILAGLPPYAKVQRNC
>NC_022576.1|WP_041194605.1|2437933_2438491_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MSHYVNMDVRPDGDFPSSQLMGALYVRLHRALVAHGAGDIGVCFPAHNEHWLGNRMRLHGSAEALGKLMGVDWLQGMRDHLDLTPVSPVPDQMGYRQVKRVQPQSSPERLRRRLMLRHKLTAEEAAERIPDTVAQLVALPSVFVRSSSTGQSFRLFVCHGPLTPEPKEGGFSTYGLSLGGAVPWF
>NC_022576.1|WP_022775599.1|2438504_2439542_-|type-I-F-CRISPR-associated-protein-Csy3
MATTNPLKTASVLAFDRKLDPSDALFAAGTWAHRANSAAWPPVAVRAKSVRGTISNRLKTKDQDPAKLDAAIENPNLQTVDVATLPAEADTLQVSFTLRVLGGTGTPSACNNADYQRVLVDTVNGYVATHGFAELARRYAANLANGRFLWRNRLGAEQIEVQVARLVDGRAANTWTFDALAHSLRGFDAPETMHPDLGAVSTLLAQGLAGKSHVLLQVTAFVRMGSGQEVYPSQELILDKDKANKSKTLYTVNGIAGMHSQKLGNAIRTIDTWYTGAADNGPIAVEPYGSVTTQGKAYRQPKQKEDFYTLLDNWVTKGQAPALEQQHFVVATLIRGGVFGDTDKG
>NC_022576.1|WP_022775602.1|2439568_2440624_-|type-I-F-CRISPR-associated-protein-Csy2
MPTDAPQHAALLVLPRLRVQNANAISSPMTWGFPAITAFSGFMAALARRLVPDAGIQFHGVGVVCHHFEAQVTQGGYVRNFHLTRNPVLADGSTAAIVEEGHIHLDITLVFDVSLAHHLQDDTTRTSLAAHVGEVVAGMRLAGGSIMPPLPGTLRRAPRAQLKLLHDETDARRAQEFRHLSRRWLPGFALVSADEVLQRTHQDALQAQAPNGTPPPTLFDTWLDLSRINHRPVKKTVWDEAIGDYQNTVTWETDKRPGWLVPIPVGFAALSALHPPGAVAGARDAATPFRFVECVYSMGQWISPHRLRDTQQMMWYAEHDAESGLYRCTNGYQVPPQSQAPLSVTPPVHQD
>NC_022576.1|WP_022775606.1|2440613_2441909_-|type-I-F-CRISPR-associated-protein-Csy1
MLTPRQAALRLLITDFLSQRLESKLEKLPPDDPKRADLQRDFAPAAWLEDAARRAAQIQVVTHSLKPIHPEAKGTNLYCPPDALAPVPVVGSHCLTDDFAGDVVGNAAALDVYKFLKQEHEGQTLLALAVSGDVDWAQALSDDPAQAQAWMSAFASLATPHGNPTSHTLAKQLYWPVGDDLHDDAGYHLLAPLYASSLAHRLYQTLQDDRFSDEAKAAREARKADLVSERPVRDYPNLAVQQLGGTKPQNISQLNSERRGQNSLLASLPPMWRSVELKPLWGTESMFPRYKSRPAVKENLGALLAFLKTDPKRNVDTRDRRAAYVDNLIDDFLQFTAEVRTLEPGWSCNNKCRLPAEQAYWLDPEGAAQADAELGRPPPTDTHERICEAYANWLNAQLRDPLPMGDPEFEAWRKAMQEHILAEEREGLHAD
>NC_022576.1|WP_022775614.1|2443298_2443742_+|EVE-domain-containing-protein
MRYWIGVASKEHVNRGVSGGFCQLCHGKAQPLKRMSVGDWIIYYSPKELFEEATPCQKFTAIGEVVGSEVYPFEMFPGFVPHRRDIHFLKASDVPIRPLLEQLSFIQDKRKWGYAFRYGHLEIPISDFELIATKMLGHVPANIHEEK
>NC_022576.1|WP_151194617.1|2443792_2444050_+|hypothetical-protein
MFRAIADINSWSKWDKGLEFTKIEGVARPGVLFVLKPKGGPNVQITIDEIKPYRLVNTAHLFLAKMRTSHDVCPIWRPNNYPIFC
>NC_022576.1|WP_022775617.1|2444200_2444683_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MKRKVYIETSVISYLTARPSKSILGTAHQQITLAWWETRSQYDLVVSELVLRECGAGDPDAAKKRLTMLNDVPLILITEQALDIANSLIAKGIVPAKAAEDALHIAISTSNRIDYLLTWNCWHIANPEMQRGISAHLDDIGLSLPFICTPEELLGEEDVE
>NC_022576.1|WP_022775620.1|2444672_2444861_+|hypothetical-protein
MWNDEILDEVRAIRDAHAAKFGYDLQAIYADLKKSEAEHIAAGHPFIPAPERPVPNRVGNGF
>NC_022576.1|WP_187292297.1|2444908_2445193_-|hypothetical-protein
MDQKAHPNVLLETVALAAHEDQELTGIGHKPEIGDSARSQQQQLLADVQNPGYQSGHIQRVVTGAGFAECERPVVQSTGIHGYETKDFVERAGL
>NC_022576.1|WP_022775630.1|2445853_2446126_+|DUF2442-domain-containing-protein
MDTIVKAVPLENYCIEVVTSSGISGVFDVKPYLSGGAFQELRTQSYFSLVRPAHHGIAWPNEQDFSSDTIIHDIQNAQHAAQAGHPECGL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_022576_1	1.10\|883210\|34\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883210-883243	34	NC_022576.1	793861-793894	0	1.0

1. spacer 1.10|883210|34|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to position: 793861-793894, mismatch: 0, identity: 1.0

ctttgtagatcagcgcattctttgcgccgctacg	CRISPR spacer
ctttgtagatcagcgcattctttgcgccgctacg	Protospacer
**********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_022576_5	5.5\|2436725\|32\|NC_022576\|CRISPRCasFinder,CRT	2436725-2436756	32	NZ_CP045191	Escherichia coli strain NT1F31 plasmid pNT1F31-113kb, complete sequence	17157-17188	6	0.812
NC_022576_5	5.5\|2436725\|32\|NC_022576\|CRISPRCasFinder,CRT	2436725-2436756	32	NZ_CP027358	Escherichia coli strain 2013C-4991 plasmid unnamed3, complete sequence	61678-61709	6	0.812
NC_022576_5	5.5\|2436725\|32\|NC_022576\|CRISPRCasFinder,CRT	2436725-2436756	32	CP053753	Shigella sonnei strain 506 plasmid pMHMC-002, complete sequence	66828-66859	6	0.812
NC_022576_5	5.5\|2436725\|32\|NC_022576\|CRISPRCasFinder,CRT	2436725-2436756	32	CP045933	Shigella sonnei strain AUSMDU00010534 plasmid pAUSMDU00010534_01, complete sequence	10115-10146	6	0.812
NC_022576_5	5.5\|2436725\|32\|NC_022576\|CRISPRCasFinder,CRT	2436725-2436756	32	NZ_CP041451	Escherichia coli strain YPE3 plasmid pYPE3-114k, complete sequence	8154-8185	6	0.812
NC_022576_5	5.5\|2436725\|32\|NC_022576\|CRISPRCasFinder,CRT	2436725-2436756	32	NZ_LR213459	Shigella sonnei strain AUSMDU00008333 isolate AUSMDU00008333 plasmid 2	10115-10146	6	0.812
NC_022576_5	5.21\|2437685\|32\|NC_022576\|CRISPRCasFinder,CRT	2437685-2437716	32	NC_048053	Dickeya phage vB_DsoM_JA29, complete genome	92760-92791	6	0.812
NC_022576_5	5.21\|2437685\|32\|NC_022576\|CRISPRCasFinder,CRT	2437685-2437716	32	MH389777	Dickeya phage vB_DsoM_JA11, complete genome	92069-92100	6	0.812
NC_022576_5	5.21\|2437685\|32\|NC_022576\|CRISPRCasFinder,CRT	2437685-2437716	32	MH460462	Dickeya phage vB_DsoM_JA33, complete genome	92059-92090	6	0.812
NC_022576_5	5.21\|2437685\|32\|NC_022576\|CRISPRCasFinder,CRT	2437685-2437716	32	MH460460	Dickeya phage vB_DsoM_JA13, complete genome	92264-92295	6	0.812
NC_022576_5	5.27\|2436727\|32\|NC_022576\|PILER-CR	2436727-2436758	32	NZ_CP045191	Escherichia coli strain NT1F31 plasmid pNT1F31-113kb, complete sequence	17157-17188	6	0.812
NC_022576_5	5.27\|2436727\|32\|NC_022576\|PILER-CR	2436727-2436758	32	NZ_CP027358	Escherichia coli strain 2013C-4991 plasmid unnamed3, complete sequence	61678-61709	6	0.812
NC_022576_5	5.27\|2436727\|32\|NC_022576\|PILER-CR	2436727-2436758	32	CP053753	Shigella sonnei strain 506 plasmid pMHMC-002, complete sequence	66828-66859	6	0.812
NC_022576_5	5.27\|2436727\|32\|NC_022576\|PILER-CR	2436727-2436758	32	CP045933	Shigella sonnei strain AUSMDU00010534 plasmid pAUSMDU00010534_01, complete sequence	10115-10146	6	0.812
NC_022576_5	5.27\|2436727\|32\|NC_022576\|PILER-CR	2436727-2436758	32	NZ_CP041451	Escherichia coli strain YPE3 plasmid pYPE3-114k, complete sequence	8154-8185	6	0.812
NC_022576_5	5.27\|2436727\|32\|NC_022576\|PILER-CR	2436727-2436758	32	NZ_LR213459	Shigella sonnei strain AUSMDU00008333 isolate AUSMDU00008333 plasmid 2	10115-10146	6	0.812
NC_022576_5	5.43\|2437687\|32\|NC_022576\|PILER-CR	2437687-2437718	32	NC_048053	Dickeya phage vB_DsoM_JA29, complete genome	92760-92791	6	0.812
NC_022576_5	5.43\|2437687\|32\|NC_022576\|PILER-CR	2437687-2437718	32	MH389777	Dickeya phage vB_DsoM_JA11, complete genome	92069-92100	6	0.812
NC_022576_5	5.43\|2437687\|32\|NC_022576\|PILER-CR	2437687-2437718	32	MH460462	Dickeya phage vB_DsoM_JA33, complete genome	92059-92090	6	0.812
NC_022576_5	5.43\|2437687\|32\|NC_022576\|PILER-CR	2437687-2437718	32	MH460460	Dickeya phage vB_DsoM_JA13, complete genome	92264-92295	6	0.812
NC_022576_5	5.6\|2436785\|32\|NC_022576\|CRISPRCasFinder,CRT	2436785-2436816	32	NZ_CP023712	Rhodococcus ruber strain YC-YT1 plasmid unnamed1, complete sequence	71174-71205	7	0.781
NC_022576_5	5.20\|2437625\|32\|NC_022576\|CRISPRCasFinder,CRT	2437625-2437656	32	NC_011961	Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence	283873-283904	7	0.781
NC_022576_5	5.28\|2436787\|32\|NC_022576\|PILER-CR	2436787-2436818	32	NZ_CP023712	Rhodococcus ruber strain YC-YT1 plasmid unnamed1, complete sequence	71174-71205	7	0.781
NC_022576_5	5.42\|2437627\|32\|NC_022576\|PILER-CR	2437627-2437658	32	NC_011961	Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence	283873-283904	7	0.781
NC_022576_2	2.3\|884824\|34\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	884824-884857	34	NZ_CP026489	Streptomyces sp. 604F plasmid unnamed, complete sequence	62585-62618	8	0.765
NC_022576_5	5.7\|2436845\|32\|NC_022576\|CRISPRCasFinder,CRT	2436845-2436876	32	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	227862-227893	8	0.75
NC_022576_5	5.12\|2437145\|32\|NC_022576\|CRISPRCasFinder,CRT	2437145-2437176	32	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	26244-26275	8	0.75
NC_022576_5	5.12\|2437145\|32\|NC_022576\|CRISPRCasFinder,CRT	2437145-2437176	32	NZ_CP038146	Streptomyces sp. S501 plasmid unnamed, complete sequence	64790-64821	8	0.75
NC_022576_5	5.12\|2437145\|32\|NC_022576\|CRISPRCasFinder,CRT	2437145-2437176	32	NZ_CP038146	Streptomyces sp. S501 plasmid unnamed, complete sequence	240213-240244	8	0.75
NC_022576_5	5.12\|2437145\|32\|NC_022576\|CRISPRCasFinder,CRT	2437145-2437176	32	NZ_CP038146	Streptomyces sp. S501 plasmid unnamed, complete sequence	263571-263602	8	0.75
NC_022576_5	5.12\|2437145\|32\|NC_022576\|CRISPRCasFinder,CRT	2437145-2437176	32	NZ_CP038146	Streptomyces sp. S501 plasmid unnamed, complete sequence	265304-265335	8	0.75
NC_022576_5	5.15\|2437325\|32\|NC_022576\|CRISPRCasFinder,CRT	2437325-2437356	32	NC_021238	Klebsiella pneumoniae strain Kpn-1433 plasmid pKP1433, complete sequence	40387-40418	8	0.75
NC_022576_5	5.15\|2437325\|32\|NC_022576\|CRISPRCasFinder,CRT	2437325-2437356	32	NZ_CP049048	Enterobacter hormaechei strain Y233 plasmid p233-142, complete sequence	79995-80026	8	0.75
NC_022576_5	5.19\|2437565\|32\|NC_022576\|CRISPRCasFinder,CRT	2437565-2437596	32	CP053403	Salmonella enterica strain 2010K-2057 plasmid unnamed1, complete sequence	59468-59499	8	0.75
NC_022576_5	5.19\|2437565\|32\|NC_022576\|CRISPRCasFinder,CRT	2437565-2437596	32	NZ_CP019182	Salmonella enterica subsp. enterica serovar Inverness str. ATCC 10720 plasmid pATCC10720, complete sequence	92418-92449	8	0.75
NC_022576_5	5.22\|2437745\|32\|NC_022576\|CRISPRCasFinder,CRT	2437745-2437776	32	NZ_CP013556	Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence	958098-958129	8	0.75
NC_022576_5	5.22\|2437745\|32\|NC_022576\|CRISPRCasFinder,CRT	2437745-2437776	32	NZ_CP013562	Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence	933455-933486	8	0.75
NC_022576_5	5.22\|2437745\|32\|NC_022576\|CRISPRCasFinder,CRT	2437745-2437776	32	NZ_CP013567	Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence	958098-958129	8	0.75
NC_022576_5	5.29\|2436847\|32\|NC_022576\|PILER-CR	2436847-2436878	32	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	227862-227893	8	0.75
NC_022576_5	5.34\|2437147\|32\|NC_022576\|PILER-CR	2437147-2437178	32	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	26244-26275	8	0.75
NC_022576_5	5.34\|2437147\|32\|NC_022576\|PILER-CR	2437147-2437178	32	NZ_CP038146	Streptomyces sp. S501 plasmid unnamed, complete sequence	64790-64821	8	0.75
NC_022576_5	5.34\|2437147\|32\|NC_022576\|PILER-CR	2437147-2437178	32	NZ_CP038146	Streptomyces sp. S501 plasmid unnamed, complete sequence	240213-240244	8	0.75
NC_022576_5	5.34\|2437147\|32\|NC_022576\|PILER-CR	2437147-2437178	32	NZ_CP038146	Streptomyces sp. S501 plasmid unnamed, complete sequence	263571-263602	8	0.75
NC_022576_5	5.34\|2437147\|32\|NC_022576\|PILER-CR	2437147-2437178	32	NZ_CP038146	Streptomyces sp. S501 plasmid unnamed, complete sequence	265304-265335	8	0.75
NC_022576_5	5.37\|2437327\|32\|NC_022576\|PILER-CR	2437327-2437358	32	NC_021238	Klebsiella pneumoniae strain Kpn-1433 plasmid pKP1433, complete sequence	40387-40418	8	0.75
NC_022576_5	5.37\|2437327\|32\|NC_022576\|PILER-CR	2437327-2437358	32	NZ_CP049048	Enterobacter hormaechei strain Y233 plasmid p233-142, complete sequence	79995-80026	8	0.75
NC_022576_5	5.41\|2437567\|32\|NC_022576\|PILER-CR	2437567-2437598	32	CP053403	Salmonella enterica strain 2010K-2057 plasmid unnamed1, complete sequence	59468-59499	8	0.75
NC_022576_5	5.41\|2437567\|32\|NC_022576\|PILER-CR	2437567-2437598	32	NZ_CP019182	Salmonella enterica subsp. enterica serovar Inverness str. ATCC 10720 plasmid pATCC10720, complete sequence	92418-92449	8	0.75
NC_022576_5	5.44\|2437747\|32\|NC_022576\|PILER-CR	2437747-2437778	32	NZ_CP013556	Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence	958098-958129	8	0.75
NC_022576_5	5.44\|2437747\|32\|NC_022576\|PILER-CR	2437747-2437778	32	NZ_CP013562	Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence	933455-933486	8	0.75
NC_022576_5	5.44\|2437747\|32\|NC_022576\|PILER-CR	2437747-2437778	32	NZ_CP013567	Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence	958098-958129	8	0.75
NC_022576_1	1.6\|882930\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	882930-882961	32	JF974306	Cyanophage P-SS1 strain P-SS1, * SEQUENCING IN PROGRESS *, 2 unordered pieces	61402-61433	9	0.719
NC_022576_1	1.6\|882930\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	882930-882961	32	HQ634176	Cyanophage P-RSM3 genomic sequence	64052-64083	9	0.719
NC_022576_1	1.6\|882930\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	882930-882961	32	AY940168	Prochlorococcus phage P-SSM4, complete genome	22150-22181	9	0.719
NC_022576_1	1.11\|883281\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883281-883312	32	NZ_CP021753	Klebsiella pneumoniae strain AR_0113 plasmid unitig_2, complete sequence	16329-16360	9	0.719
NC_022576_1	1.11\|883281\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883281-883312	32	NZ_CP008791	Klebsiella oxytoca KONIH1 plasmid pKPC-727, complete sequence	196694-196725	9	0.719
NC_022576_1	1.11\|883281\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883281-883312	32	NZ_CP025040	Klebsiella pneumoniae strain NU-CRE047 plasmid pNU-CRE047_3, complete sequence	17507-17538	9	0.719
NC_022576_1	1.11\|883281\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883281-883312	32	KY940546	Klebsiella pneumoniae plasmid pUCLA3, complete sequence	49646-49677	9	0.719
NC_022576_1	1.11\|883281\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883281-883312	32	NZ_CP021545	Klebsiella pneumoniae strain AR_0112 plasmid tig00000001, complete sequence	99718-99749	9	0.719
NC_022576_1	1.11\|883281\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883281-883312	32	NZ_CP006922	Klebsiella pneumoniae 30684/NJST258_2 plasmid pNJST258C1, complete sequence	28074-28105	9	0.719
NC_022576_1	1.11\|883281\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883281-883312	32	NZ_CP020064	Klebsiella pneumoniae strain AR_0117 plasmid unitig_3, complete sequence	55957-55988	9	0.719
NC_022576_1	1.11\|883281\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883281-883312	32	NZ_CP021857	Klebsiella pneumoniae strain AR_0125 plasmid tig00000002_pilon, complete sequence	88137-88168	9	0.719
NC_022576_1	1.15\|883560\|33\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883560-883592	33	NC_010181	Bacillus mycoides KBAB4 plasmid pBWB402, complete sequence	27447-27479	9	0.727
NC_022576_2	2.7\|885106\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	885106-885137	32	CP011075	Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence	152851-152882	9	0.719
NC_022576_2	2.7\|885106\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	885106-885137	32	MG516912	Proteus penneri plasmid pPp47, complete sequence	52167-52198	9	0.719
NC_022576_2	2.7\|885106\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	885106-885137	32	NZ_CP045540	Proteus mirabilis strain CRE14IB plasmid pIB_NDM_1, complete sequence	46271-46302	9	0.719
NC_022576_2	2.7\|885106\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	885106-885137	32	NZ_LC507075	Providencia rettgeri strain BML2526 plasmid p.BML2526, complete sequence	94532-94563	9	0.719
NC_022576_2	2.8\|885175\|32\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	885175-885206	32	NZ_CP040452	Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence	1783618-1783649	9	0.719
NC_022576_5	5.1\|2436483\|32\|NC_022576\|CRISPRCasFinder,CRT	2436483-2436514	32	NZ_CP021405	Celeribacter manganoxidans strain DY25 plasmid pDY25-A, complete sequence	125462-125493	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MF668281	Mycobacterium phage RitaG, complete genome	48239-48270	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MT684597	Mycobacterium phage Mandlovu, complete genome	44769-44800	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KY012363	Mycobacterium phage Empress, complete genome	47117-47148	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MH371123	Mycobacterium phage Sandalphon, complete genome	46713-46744	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MH669010	Mycobacterium phage PHappiness, complete genome	48437-48468	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MN585973	Mycobacterium phage StAnnes, complete genome	47403-47434	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MH077578	Mycobacterium phage DillTech15, complete genome	45809-45840	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MH020235	Mycobacterium phage Batiatus, complete genome	47286-47317	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KY471267	Mycobacterium phage SassyB, complete genome	43951-43982	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KM597530	Mycobacterium phage Bipolar, complete genome	48930-48961	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MN428047	Mycobacterium phage Doomphist, complete genome	48306-48337	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KT281793	Mycobacterium phage Seagreen, complete genome	48061-48092	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MN369755	Mycobacterium phage Minnie, complete genome	48728-48759	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MF668271	Mycobacterium phage Geralt, complete genome	46213-46244	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	NC_041855	Mycobacterium phage Dorothy, complete genome	48944-48975	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KM101124	Mycobacterium phage Squirty, complete genome	50342-50373	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MN735433	Mycobacterium phage Scottish, complete genome	46787-46818	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MG770213	Mycobacterium phage OldBen, complete genome	47608-47639	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	NC_028961	Mycobacterium phage PopTart, complete genome	43951-43982	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	NC_041989	Mycobacterium phage Shauna1, complete genome	47415-47446	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KR997968	Mycobacterium phage Quico, complete genome	49579-49610	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MH669009	Mycobacterium phage Nimbo, complete genome	46216-46247	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MH651178	Mycobacterium phage KristaRAM, complete genome	46232-46263	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MH669001	Mycobacterium phage EleanorGeorge, complete genome	47899-47930	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MK305886	Mycobacterium phage Poenanya, complete genome	48306-48337	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MK016494	Mycobacterium phage Filuzino, complete genome	48843-48874	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KM066034	Mycobacterium phage Inventum, complete genome	47129-47160	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MH632119	Mycobacterium phage Harley, complete genome	46447-46478	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MG925354	Mycobacterium phage Ogopogo, complete genome	46733-46764	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KY702574	Mycobacterium phage Kingsley, complete genome	49369-49400	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	NC_021301	Mycobacterium phage SiSi, complete genome	46245-46276	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MN369752	Mycobacterium phage Flathead, complete genome	46557-46588	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MN310548	Mycobacterium phage Juice456, complete genome	45863-45894	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KR997930	Mycobacterium phage Florinda, complete genome	49759-49790	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	HQ728524	Mycobacterium phage Wee, complete genome	48945-48976	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MH669005	Mycobacterium phage JoeyJr, complete genome	48118-48149	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MK875792	Mycobacterium phage Polka14, complete genome	49096-49127	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KF114874	Mycobacterium phage Bobi, complete genome	49585-49616	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	NC_023728	Mycobacterium virus DeadP, complete genome	46112-46143	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	JN699012	Mycobacterium phage SG4, complete genome	46014-46045	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MN586004	Mycobacterium phage Strokeseat, complete genome	44826-44857	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	KR997931	Mycobacterium phage Girafales, complete genome	49364-49395	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MN204502	Mycobacterium phage KingMidas, complete genome	47532-47563	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MT684601	Mycobacterium phage Hlubikazi, complete genome	44827-44858	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	MT114167	Mycobacterium phage Phanphagia, complete genome	47165-47196	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	NC_022068	Mycobacteriophage Daenerys, complete genome	48493-48524	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	JF937093	Mycobacterium virus DLane, complete genome	46864-46895	9	0.719
NC_022576_5	5.2\|2436543\|32\|NC_022576\|CRISPRCasFinder,CRT	2436543-2436574	32	NC_025433	Mycobacteriophage Taj, complete genome	48869-48900	9	0.719
NC_022576_5	5.20\|2437625\|32\|NC_022576\|CRISPRCasFinder,CRT	2437625-2437656	32	NZ_LT960613	Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 plasmid P, complete sequence	39578-39609	9	0.719
NC_022576_5	5.23\|2436485\|32\|NC_022576\|PILER-CR	2436485-2436516	32	NZ_CP021405	Celeribacter manganoxidans strain DY25 plasmid pDY25-A, complete sequence	125462-125493	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MF668281	Mycobacterium phage RitaG, complete genome	48239-48270	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MT684597	Mycobacterium phage Mandlovu, complete genome	44769-44800	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KY012363	Mycobacterium phage Empress, complete genome	47117-47148	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MH371123	Mycobacterium phage Sandalphon, complete genome	46713-46744	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MH669010	Mycobacterium phage PHappiness, complete genome	48437-48468	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MN585973	Mycobacterium phage StAnnes, complete genome	47403-47434	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MH077578	Mycobacterium phage DillTech15, complete genome	45809-45840	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MH020235	Mycobacterium phage Batiatus, complete genome	47286-47317	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KY471267	Mycobacterium phage SassyB, complete genome	43951-43982	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KM597530	Mycobacterium phage Bipolar, complete genome	48930-48961	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MN428047	Mycobacterium phage Doomphist, complete genome	48306-48337	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KT281793	Mycobacterium phage Seagreen, complete genome	48061-48092	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MN369755	Mycobacterium phage Minnie, complete genome	48728-48759	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MF668271	Mycobacterium phage Geralt, complete genome	46213-46244	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	NC_041855	Mycobacterium phage Dorothy, complete genome	48944-48975	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KM101124	Mycobacterium phage Squirty, complete genome	50342-50373	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MN735433	Mycobacterium phage Scottish, complete genome	46787-46818	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MG770213	Mycobacterium phage OldBen, complete genome	47608-47639	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	NC_028961	Mycobacterium phage PopTart, complete genome	43951-43982	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	NC_041989	Mycobacterium phage Shauna1, complete genome	47415-47446	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KR997968	Mycobacterium phage Quico, complete genome	49579-49610	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MH669009	Mycobacterium phage Nimbo, complete genome	46216-46247	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MH651178	Mycobacterium phage KristaRAM, complete genome	46232-46263	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MH669001	Mycobacterium phage EleanorGeorge, complete genome	47899-47930	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MK305886	Mycobacterium phage Poenanya, complete genome	48306-48337	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MK016494	Mycobacterium phage Filuzino, complete genome	48843-48874	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KM066034	Mycobacterium phage Inventum, complete genome	47129-47160	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MH632119	Mycobacterium phage Harley, complete genome	46447-46478	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MG925354	Mycobacterium phage Ogopogo, complete genome	46733-46764	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KY702574	Mycobacterium phage Kingsley, complete genome	49369-49400	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	NC_021301	Mycobacterium phage SiSi, complete genome	46245-46276	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MN369752	Mycobacterium phage Flathead, complete genome	46557-46588	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MN310548	Mycobacterium phage Juice456, complete genome	45863-45894	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KR997930	Mycobacterium phage Florinda, complete genome	49759-49790	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	HQ728524	Mycobacterium phage Wee, complete genome	48945-48976	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MH669005	Mycobacterium phage JoeyJr, complete genome	48118-48149	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MK875792	Mycobacterium phage Polka14, complete genome	49096-49127	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KF114874	Mycobacterium phage Bobi, complete genome	49585-49616	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	NC_023728	Mycobacterium virus DeadP, complete genome	46112-46143	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	JN699012	Mycobacterium phage SG4, complete genome	46014-46045	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MN586004	Mycobacterium phage Strokeseat, complete genome	44826-44857	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	KR997931	Mycobacterium phage Girafales, complete genome	49364-49395	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MN204502	Mycobacterium phage KingMidas, complete genome	47532-47563	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MT684601	Mycobacterium phage Hlubikazi, complete genome	44827-44858	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	MT114167	Mycobacterium phage Phanphagia, complete genome	47165-47196	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	NC_022068	Mycobacteriophage Daenerys, complete genome	48493-48524	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	JF937093	Mycobacterium virus DLane, complete genome	46864-46895	9	0.719
NC_022576_5	5.24\|2436545\|32\|NC_022576\|PILER-CR	2436545-2436576	32	NC_025433	Mycobacteriophage Taj, complete genome	48869-48900	9	0.719
NC_022576_5	5.42\|2437627\|32\|NC_022576\|PILER-CR	2437627-2437658	32	NZ_LT960613	Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 plasmid P, complete sequence	39578-39609	9	0.719
NC_022576_1	1.10\|883210\|34\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	883210-883243	34	NC_023136	Leisingera methylohalidivorans DSM 14336 plasmid unnamed, complete sequence	277776-277809	10	0.706
NC_022576_2	2.2\|884753\|34\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	884753-884786	34	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	1279381-1279414	10	0.706
NC_022576_2	2.2\|884753\|34\|NC_022576\|PILER-CR,CRISPRCasFinder,CRT	884753-884786	34	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	2347921-2347954	10	0.706
NC_022576_5	5.6\|2436785\|32\|NC_022576\|CRISPRCasFinder,CRT	2436785-2436816	32	NZ_CP022191	Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence	389190-389221	10	0.688
NC_022576_5	5.19\|2437565\|32\|NC_022576\|CRISPRCasFinder,CRT	2437565-2437596	32	NZ_CP024166	Salmonella enterica subsp. enterica serovar Gaminara strain CFSAN070644 plasmid pCFSAN024441_01, complete sequence	26573-26604	10	0.688
NC_022576_5	5.19\|2437565\|32\|NC_022576\|CRISPRCasFinder,CRT	2437565-2437596	32	MH572517	Microviridae sp. isolate SD_HF_67, complete genome	1-30	10	0.688
NC_022576_5	5.21\|2437685\|32\|NC_022576\|CRISPRCasFinder,CRT	2437685-2437716	32	NZ_CP054029	Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence	311294-311325	10	0.688
NC_022576_5	5.28\|2436787\|32\|NC_022576\|PILER-CR	2436787-2436818	32	NZ_CP022191	Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence	389190-389221	10	0.688
NC_022576_5	5.41\|2437567\|32\|NC_022576\|PILER-CR	2437567-2437598	32	NZ_CP024166	Salmonella enterica subsp. enterica serovar Gaminara strain CFSAN070644 plasmid pCFSAN024441_01, complete sequence	26573-26604	10	0.688
NC_022576_5	5.41\|2437567\|32\|NC_022576\|PILER-CR	2437567-2437598	32	MH572517	Microviridae sp. isolate SD_HF_67, complete genome	1-30	10	0.688
NC_022576_5	5.43\|2437687\|32\|NC_022576\|PILER-CR	2437687-2437718	32	NZ_CP054029	Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence	311294-311325	10	0.688

1. spacer 5.5|2436725|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP045191 (Escherichia coli strain NT1F31 plasmid pNT1F31-113kb, complete sequence) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

2. spacer 5.5|2436725|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP027358 (Escherichia coli strain 2013C-4991 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

3. spacer 5.5|2436725|32|NC_022576|CRISPRCasFinder,CRT matches to CP053753 (Shigella sonnei strain 506 plasmid pMHMC-002, complete sequence) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

4. spacer 5.5|2436725|32|NC_022576|CRISPRCasFinder,CRT matches to CP045933 (Shigella sonnei strain AUSMDU00010534 plasmid pAUSMDU00010534_01, complete sequence) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

5. spacer 5.5|2436725|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP041451 (Escherichia coli strain YPE3 plasmid pYPE3-114k, complete sequence) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

6. spacer 5.5|2436725|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_LR213459 (Shigella sonnei strain AUSMDU00008333 isolate AUSMDU00008333 plasmid 2) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

7. spacer 5.21|2437685|32|NC_022576|CRISPRCasFinder,CRT matches to NC_048053 (Dickeya phage vB_DsoM_JA29, complete genome) position: , mismatch: 6, identity: 0.812

attgacatgccagccgtaacgcttgctgaatt	CRISPR spacer
ataattatgcctgccgtaacgcttactgaatt	Protospacer
** . .***** ************.*******

8. spacer 5.21|2437685|32|NC_022576|CRISPRCasFinder,CRT matches to MH389777 (Dickeya phage vB_DsoM_JA11, complete genome) position: , mismatch: 6, identity: 0.812

attgacatgccagccgtaacgcttgctgaatt	CRISPR spacer
ataattatgcctgccgtaacgcttactgaatt	Protospacer
** . .***** ************.*******

9. spacer 5.21|2437685|32|NC_022576|CRISPRCasFinder,CRT matches to MH460462 (Dickeya phage vB_DsoM_JA33, complete genome) position: , mismatch: 6, identity: 0.812

attgacatgccagccgtaacgcttgctgaatt	CRISPR spacer
ataattatgcctgccgtaacgcttactgaatt	Protospacer
** . .***** ************.*******

10. spacer 5.21|2437685|32|NC_022576|CRISPRCasFinder,CRT matches to MH460460 (Dickeya phage vB_DsoM_JA13, complete genome) position: , mismatch: 6, identity: 0.812

attgacatgccagccgtaacgcttgctgaatt	CRISPR spacer
ataattatgcctgccgtaacgcttactgaatt	Protospacer
** . .***** ************.*******

11. spacer 5.27|2436727|32|NC_022576|PILER-CR matches to NZ_CP045191 (Escherichia coli strain NT1F31 plasmid pNT1F31-113kb, complete sequence) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

12. spacer 5.27|2436727|32|NC_022576|PILER-CR matches to NZ_CP027358 (Escherichia coli strain 2013C-4991 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

13. spacer 5.27|2436727|32|NC_022576|PILER-CR matches to CP053753 (Shigella sonnei strain 506 plasmid pMHMC-002, complete sequence) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

14. spacer 5.27|2436727|32|NC_022576|PILER-CR matches to CP045933 (Shigella sonnei strain AUSMDU00010534 plasmid pAUSMDU00010534_01, complete sequence) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

15. spacer 5.27|2436727|32|NC_022576|PILER-CR matches to NZ_CP041451 (Escherichia coli strain YPE3 plasmid pYPE3-114k, complete sequence) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

16. spacer 5.27|2436727|32|NC_022576|PILER-CR matches to NZ_LR213459 (Shigella sonnei strain AUSMDU00008333 isolate AUSMDU00008333 plasmid 2) position: , mismatch: 6, identity: 0.812

tctgctacgtgcagtgcgtcatcc--cctctagc	CRISPR spacer
tctgctatgtgccgtgcgtcatccaacttctg--	Protospacer
*******.**** ***********  *.***.

17. spacer 5.43|2437687|32|NC_022576|PILER-CR matches to NC_048053 (Dickeya phage vB_DsoM_JA29, complete genome) position: , mismatch: 6, identity: 0.812

attgacatgccagccgtaacgcttgctgaatt	CRISPR spacer
ataattatgcctgccgtaacgcttactgaatt	Protospacer
** . .***** ************.*******

18. spacer 5.43|2437687|32|NC_022576|PILER-CR matches to MH389777 (Dickeya phage vB_DsoM_JA11, complete genome) position: , mismatch: 6, identity: 0.812

attgacatgccagccgtaacgcttgctgaatt	CRISPR spacer
ataattatgcctgccgtaacgcttactgaatt	Protospacer
** . .***** ************.*******

19. spacer 5.43|2437687|32|NC_022576|PILER-CR matches to MH460462 (Dickeya phage vB_DsoM_JA33, complete genome) position: , mismatch: 6, identity: 0.812

attgacatgccagccgtaacgcttgctgaatt	CRISPR spacer
ataattatgcctgccgtaacgcttactgaatt	Protospacer
** . .***** ************.*******

20. spacer 5.43|2437687|32|NC_022576|PILER-CR matches to MH460460 (Dickeya phage vB_DsoM_JA13, complete genome) position: , mismatch: 6, identity: 0.812

attgacatgccagccgtaacgcttgctgaatt	CRISPR spacer
ataattatgcctgccgtaacgcttactgaatt	Protospacer
** . .***** ************.*******

21. spacer 5.6|2436785|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP023712 (Rhodococcus ruber strain YC-YT1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

--ttctcatcgcgtgcgcagggctgctgctatgg	CRISPR spacer
gacggtcat--cgtgagcagggctgctgccatgg	Protospacer
  .  ****  **** *************.****

22. spacer 5.20|2437625|32|NC_022576|CRISPRCasFinder,CRT matches to NC_011961 (Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

--tgactcgtcgcgcctatctttttgctttttca	CRISPR spacer
ggtggatc--cgcgcctatcttgtcgctttttcg	Protospacer
  **. **  ************ *.********.

23. spacer 5.28|2436787|32|NC_022576|PILER-CR matches to NZ_CP023712 (Rhodococcus ruber strain YC-YT1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

--ttctcatcgcgtgcgcagggctgctgctatgg	CRISPR spacer
gacggtcat--cgtgagcagggctgctgccatgg	Protospacer
  .  ****  **** *************.****

24. spacer 5.42|2437627|32|NC_022576|PILER-CR matches to NC_011961 (Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

--tgactcgtcgcgcctatctttttgctttttca	CRISPR spacer
ggtggatc--cgcgcctatcttgtcgctttttcg	Protospacer
  **. **  ************ *.********.

25. spacer 2.3|884824|34|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026489 (Streptomyces sp. 604F plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

ccccttttcaggaagtgtatcgaaatctggttca	CRISPR spacer
tccacgtccaggaagggtatcgaaatctgtttcc	Protospacer
.** . *.******* ************* ***

26. spacer 5.7|2436845|32|NC_022576|CRISPRCasFinder,CRT matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 8, identity: 0.75

ccggaatggacggttcgcggcctcacttcagc	CRISPR spacer
acggaatggacggttcgcgtcctctatggccc	Protospacer
 ****************** ****  *    *

27. spacer 5.12|2437145|32|NC_022576|CRISPRCasFinder,CRT matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 8, identity: 0.75

gcatcctcggcgttagccgcac--gttcccggct	CRISPR spacer
gcatcctcggcgtgagccgctcgagcttctag--	Protospacer
************* ****** *  *.*.*..*

28. spacer 5.12|2437145|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP038146 (Streptomyces sp. S501 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gcatcctcggcgttagccgcacgttcccggct-----	CRISPR spacer
gcatcctcggcgtcagccgctcg-----agcttctac	Protospacer
*************.****** **     .***

29. spacer 5.12|2437145|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP038146 (Streptomyces sp. S501 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gcatcctcggcgttagccgcacgttcccggct-----	CRISPR spacer
gcatcctcggcgtcagccgctcg-----agcttctac	Protospacer
*************.****** **     .***

30. spacer 5.12|2437145|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP038146 (Streptomyces sp. S501 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gcatcctcggcgttagccgcacgttcccggct-----	CRISPR spacer
gcatcctcggcgtcagccgctcg-----agcttctac	Protospacer
*************.****** **     .***

31. spacer 5.12|2437145|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP038146 (Streptomyces sp. S501 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gcatcctcggcgttagccgcacgttcccggct-----	CRISPR spacer
gcatcctcggcgtcagccgctcg-----agcttctac	Protospacer
*************.****** **     .***

32. spacer 5.15|2437325|32|NC_022576|CRISPRCasFinder,CRT matches to NC_021238 (Klebsiella pneumoniae strain Kpn-1433 plasmid pKP1433, complete sequence) position: , mismatch: 8, identity: 0.75

---gcgcgcttcaaacaggaaccggttacgctctt	CRISPR spacer
tctgcg---atcaaacagaaacctgttacgctccg	Protospacer
   ***    ********.**** *********.

33. spacer 5.15|2437325|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP049048 (Enterobacter hormaechei strain Y233 plasmid p233-142, complete sequence) position: , mismatch: 8, identity: 0.75

---gcgcgcttcaaacaggaaccggttacgctctt	CRISPR spacer
tctgcg---atcaaacagaaacctgttacgctccg	Protospacer
   ***    ********.**** *********.

34. spacer 5.19|2437565|32|NC_022576|CRISPRCasFinder,CRT matches to CP053403 (Salmonella enterica strain 2010K-2057 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aattctggccattgtgtgttgtttttgcaaat---	CRISPR spacer
ttttctggccagtgtgtgtggttttt---tatctg	Protospacer
  ********* ******* ******    **

35. spacer 5.19|2437565|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP019182 (Salmonella enterica subsp. enterica serovar Inverness str. ATCC 10720 plasmid pATCC10720, complete sequence) position: , mismatch: 8, identity: 0.75

aattctggccattgtgtgttgtttttgcaaat---	CRISPR spacer
ttttctggccagtgtgtgtggttttt---tatctg	Protospacer
  ********* ******* ******    **

36. spacer 5.22|2437745|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP013556 (Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence) position: , mismatch: 8, identity: 0.75

ggatgttgttaccttccacggccttgcccgtt	CRISPR spacer
cgatgttgttcccttcctcggccttcaaggct	Protospacer
 ********* ****** *******    *.*

37. spacer 5.22|2437745|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP013562 (Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence) position: , mismatch: 8, identity: 0.75

ggatgttgttaccttccacggccttgcccgtt	CRISPR spacer
cgatgttgttcccttcctcggccttcaaggct	Protospacer
 ********* ****** *******    *.*

38. spacer 5.22|2437745|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP013567 (Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence) position: , mismatch: 8, identity: 0.75

ggatgttgttaccttccacggccttgcccgtt	CRISPR spacer
cgatgttgttcccttcctcggccttcaaggct	Protospacer
 ********* ****** *******    *.*

39. spacer 5.29|2436847|32|NC_022576|PILER-CR matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 8, identity: 0.75

ccggaatggacggttcgcggcctcacttcagc	CRISPR spacer
acggaatggacggttcgcgtcctctatggccc	Protospacer
 ****************** ****  *    *

40. spacer 5.34|2437147|32|NC_022576|PILER-CR matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 8, identity: 0.75

gcatcctcggcgttagccgcac--gttcccggct	CRISPR spacer
gcatcctcggcgtgagccgctcgagcttctag--	Protospacer
************* ****** *  *.*.*..*

41. spacer 5.34|2437147|32|NC_022576|PILER-CR matches to NZ_CP038146 (Streptomyces sp. S501 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gcatcctcggcgttagccgcacgttcccggct-----	CRISPR spacer
gcatcctcggcgtcagccgctcg-----agcttctac	Protospacer
*************.****** **     .***

42. spacer 5.34|2437147|32|NC_022576|PILER-CR matches to NZ_CP038146 (Streptomyces sp. S501 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gcatcctcggcgttagccgcacgttcccggct-----	CRISPR spacer
gcatcctcggcgtcagccgctcg-----agcttctac	Protospacer
*************.****** **     .***

43. spacer 5.34|2437147|32|NC_022576|PILER-CR matches to NZ_CP038146 (Streptomyces sp. S501 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gcatcctcggcgttagccgcacgttcccggct-----	CRISPR spacer
gcatcctcggcgtcagccgctcg-----agcttctac	Protospacer
*************.****** **     .***

44. spacer 5.34|2437147|32|NC_022576|PILER-CR matches to NZ_CP038146 (Streptomyces sp. S501 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gcatcctcggcgttagccgcacgttcccggct-----	CRISPR spacer
gcatcctcggcgtcagccgctcg-----agcttctac	Protospacer
*************.****** **     .***

45. spacer 5.37|2437327|32|NC_022576|PILER-CR matches to NC_021238 (Klebsiella pneumoniae strain Kpn-1433 plasmid pKP1433, complete sequence) position: , mismatch: 8, identity: 0.75

---gcgcgcttcaaacaggaaccggttacgctctt	CRISPR spacer
tctgcg---atcaaacagaaacctgttacgctccg	Protospacer
   ***    ********.**** *********.

46. spacer 5.37|2437327|32|NC_022576|PILER-CR matches to NZ_CP049048 (Enterobacter hormaechei strain Y233 plasmid p233-142, complete sequence) position: , mismatch: 8, identity: 0.75

---gcgcgcttcaaacaggaaccggttacgctctt	CRISPR spacer
tctgcg---atcaaacagaaacctgttacgctccg	Protospacer
   ***    ********.**** *********.

47. spacer 5.41|2437567|32|NC_022576|PILER-CR matches to CP053403 (Salmonella enterica strain 2010K-2057 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aattctggccattgtgtgttgtttttgcaaat---	CRISPR spacer
ttttctggccagtgtgtgtggttttt---tatctg	Protospacer
  ********* ******* ******    **

48. spacer 5.41|2437567|32|NC_022576|PILER-CR matches to NZ_CP019182 (Salmonella enterica subsp. enterica serovar Inverness str. ATCC 10720 plasmid pATCC10720, complete sequence) position: , mismatch: 8, identity: 0.75

aattctggccattgtgtgttgtttttgcaaat---	CRISPR spacer
ttttctggccagtgtgtgtggttttt---tatctg	Protospacer
  ********* ******* ******    **

49. spacer 5.44|2437747|32|NC_022576|PILER-CR matches to NZ_CP013556 (Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence) position: , mismatch: 8, identity: 0.75

ggatgttgttaccttccacggccttgcccgtt	CRISPR spacer
cgatgttgttcccttcctcggccttcaaggct	Protospacer
 ********* ****** *******    *.*

50. spacer 5.44|2437747|32|NC_022576|PILER-CR matches to NZ_CP013562 (Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence) position: , mismatch: 8, identity: 0.75

ggatgttgttaccttccacggccttgcccgtt	CRISPR spacer
cgatgttgttcccttcctcggccttcaaggct	Protospacer
 ********* ****** *******    *.*

51. spacer 5.44|2437747|32|NC_022576|PILER-CR matches to NZ_CP013567 (Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence) position: , mismatch: 8, identity: 0.75

ggatgttgttaccttccacggccttgcccgtt	CRISPR spacer
cgatgttgttcccttcctcggccttcaaggct	Protospacer
 ********* ****** *******    *.*

52. spacer 1.6|882930|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to JF974306 (Cyanophage P-SS1 strain P-SS1, *** SEQUENCING IN PROGRESS ***, 2 unordered pieces) position: , mismatch: 9, identity: 0.719

ttattcaggatctgttgatgcatc-----gcattacc	CRISPR spacer
gtattcagcacctgttgatgcatctgcaagta-----	Protospacer
 ******* *.*************     *.*

53. spacer 1.6|882930|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to HQ634176 (Cyanophage P-RSM3 genomic sequence) position: , mismatch: 9, identity: 0.719

ttattcaggatctgttgatgcatc-----gcattacc	CRISPR spacer
gtattcagcacctgttgatgcatctgcaagta-----	Protospacer
 ******* *.*************     *.*

54. spacer 1.6|882930|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to AY940168 (Prochlorococcus phage P-SSM4, complete genome) position: , mismatch: 9, identity: 0.719

ttattcaggatctgttgatgcatc-----gcattacc	CRISPR spacer
gtattcagcacctgttgatgcatctgcaagta-----	Protospacer
 ******* *.*************     *.*

55. spacer 1.11|883281|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021753 (Klebsiella pneumoniae strain AR_0113 plasmid unitig_2, complete sequence) position: , mismatch: 9, identity: 0.719

aatataaagtctacttgtaatgctt----aaatctt	CRISPR spacer
ggcataaagtctccttgtaattcttactaaaa----	Protospacer
...********* ******** ***    ***

56. spacer 1.11|883281|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP008791 (Klebsiella oxytoca KONIH1 plasmid pKPC-727, complete sequence) position: , mismatch: 9, identity: 0.719

aatataaagtctacttgtaatgctt----aaatctt	CRISPR spacer
ggcataaagtctccttgtaattcttactaaaa----	Protospacer
...********* ******** ***    ***

57. spacer 1.11|883281|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025040 (Klebsiella pneumoniae strain NU-CRE047 plasmid pNU-CRE047_3, complete sequence) position: , mismatch: 9, identity: 0.719

aatataaagtctacttgtaatgctt----aaatctt	CRISPR spacer
ggcataaagtctccttgtaattcttactaaaa----	Protospacer
...********* ******** ***    ***

58. spacer 1.11|883281|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to KY940546 (Klebsiella pneumoniae plasmid pUCLA3, complete sequence) position: , mismatch: 9, identity: 0.719

aatataaagtctacttgtaatgctt----aaatctt	CRISPR spacer
ggcataaagtctccttgtaattcttactaaaa----	Protospacer
...********* ******** ***    ***

59. spacer 1.11|883281|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021545 (Klebsiella pneumoniae strain AR_0112 plasmid tig00000001, complete sequence) position: , mismatch: 9, identity: 0.719

aatataaagtctacttgtaatgctt----aaatctt	CRISPR spacer
ggcataaagtctccttgtaattcttactaaaa----	Protospacer
...********* ******** ***    ***

60. spacer 1.11|883281|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006922 (Klebsiella pneumoniae 30684/NJST258_2 plasmid pNJST258C1, complete sequence) position: , mismatch: 9, identity: 0.719

aatataaagtctacttgtaatgctt----aaatctt	CRISPR spacer
ggcataaagtctccttgtaattcttactaaaa----	Protospacer
...********* ******** ***    ***

61. spacer 1.11|883281|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020064 (Klebsiella pneumoniae strain AR_0117 plasmid unitig_3, complete sequence) position: , mismatch: 9, identity: 0.719

aatataaagtctacttgtaatgctt----aaatctt	CRISPR spacer
ggcataaagtctccttgtaattcttactaaaa----	Protospacer
...********* ******** ***    ***

62. spacer 1.11|883281|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021857 (Klebsiella pneumoniae strain AR_0125 plasmid tig00000002_pilon, complete sequence) position: , mismatch: 9, identity: 0.719

aatataaagtctacttgtaatgctt----aaatctt	CRISPR spacer
ggcataaagtctccttgtaattcttactaaaa----	Protospacer
...********* ******** ***    ***

63. spacer 1.15|883560|33|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NC_010181 (Bacillus mycoides KBAB4 plasmid pBWB402, complete sequence) position: , mismatch: 9, identity: 0.727

agaaacttaattacagggtatttaatactctta	CRISPR spacer
cataacttatttacagggtaattaataccgatt	Protospacer
 . ****** ********** *******.  *

64. spacer 2.7|885106|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to CP011075 (Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

tcttccaatgcatagaaaaatgaggccattac	CRISPR spacer
cgtatcaatgcctagaaatatgaggccaaatc	Protospacer
. * .****** ****** *********   *

65. spacer 2.7|885106|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to MG516912 (Proteus penneri plasmid pPp47, complete sequence) position: , mismatch: 9, identity: 0.719

tcttccaatgcatagaaaaatgaggccattac	CRISPR spacer
tcttccaatgcaaaaaaaaatgaaagtaaaaa	Protospacer
************ *.********.. .*  *

66. spacer 2.7|885106|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045540 (Proteus mirabilis strain CRE14IB plasmid pIB_NDM_1, complete sequence) position: , mismatch: 9, identity: 0.719

tcttccaatgcatagaaaaatgaggccattac	CRISPR spacer
tcttccaatgcaaaaaaaaatgaaagtaaaaa	Protospacer
************ *.********.. .*  *

67. spacer 2.7|885106|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LC507075 (Providencia rettgeri strain BML2526 plasmid p.BML2526, complete sequence) position: , mismatch: 9, identity: 0.719

tcttccaatgcatagaaaaatgaggccattac	CRISPR spacer
tcttccaatgcaaaaaaaaatgaaagtaaaaa	Protospacer
************ *.********.. .*  *

68. spacer 2.8|885175|32|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040452 (Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

atttttggcttacctagccttcgccactcttt	CRISPR spacer
atttttgccttatctagccttcgctcggcgac	Protospacer
******* ****.***********.   *  .

69. spacer 5.1|2436483|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP021405 (Celeribacter manganoxidans strain DY25 plasmid pDY25-A, complete sequence) position: , mismatch: 9, identity: 0.719

tcgatcacgccctcggcggattgctctggtgt	CRISPR spacer
tcgatcacgccatcggcggaatggctggcgat	Protospacer
*********** ******** ** .. *  .*

70. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MF668281 (Mycobacterium phage RitaG, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

71. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MT684597 (Mycobacterium phage Mandlovu, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

72. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KY012363 (Mycobacterium phage Empress, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

73. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MH371123 (Mycobacterium phage Sandalphon, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

74. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MH669010 (Mycobacterium phage PHappiness, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

75. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MN585973 (Mycobacterium phage StAnnes, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

76. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MH077578 (Mycobacterium phage DillTech15, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

77. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MH020235 (Mycobacterium phage Batiatus, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

78. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KY471267 (Mycobacterium phage SassyB, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

79. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KM597530 (Mycobacterium phage Bipolar, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

80. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MN428047 (Mycobacterium phage Doomphist, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

81. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KT281793 (Mycobacterium phage Seagreen, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

82. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MN369755 (Mycobacterium phage Minnie, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

83. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MF668271 (Mycobacterium phage Geralt, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

84. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to NC_041855 (Mycobacterium phage Dorothy, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

85. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KM101124 (Mycobacterium phage Squirty, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

86. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MN735433 (Mycobacterium phage Scottish, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

87. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MG770213 (Mycobacterium phage OldBen, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

88. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to NC_028961 (Mycobacterium phage PopTart, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

89. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to NC_041989 (Mycobacterium phage Shauna1, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

90. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KR997968 (Mycobacterium phage Quico, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

91. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MH669009 (Mycobacterium phage Nimbo, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

92. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MH651178 (Mycobacterium phage KristaRAM, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

93. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MH669001 (Mycobacterium phage EleanorGeorge, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

94. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MK305886 (Mycobacterium phage Poenanya, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

95. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MK016494 (Mycobacterium phage Filuzino, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

96. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KM066034 (Mycobacterium phage Inventum, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

97. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MH632119 (Mycobacterium phage Harley, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

98. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MG925354 (Mycobacterium phage Ogopogo, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

99. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KY702574 (Mycobacterium phage Kingsley, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

100. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to NC_021301 (Mycobacterium phage SiSi, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

101. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MN369752 (Mycobacterium phage Flathead, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

102. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MN310548 (Mycobacterium phage Juice456, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

103. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KR997930 (Mycobacterium phage Florinda, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

104. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to HQ728524 (Mycobacterium phage Wee, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

105. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MH669005 (Mycobacterium phage JoeyJr, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

106. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MK875792 (Mycobacterium phage Polka14, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

107. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KF114874 (Mycobacterium phage Bobi, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

108. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to NC_023728 (Mycobacterium virus DeadP, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

109. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to JN699012 (Mycobacterium phage SG4, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

110. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MN586004 (Mycobacterium phage Strokeseat, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

111. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to KR997931 (Mycobacterium phage Girafales, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

112. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MN204502 (Mycobacterium phage KingMidas, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

113. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MT684601 (Mycobacterium phage Hlubikazi, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

114. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to MT114167 (Mycobacterium phage Phanphagia, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

115. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to NC_022068 (Mycobacteriophage Daenerys, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

116. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to JF937093 (Mycobacterium virus DLane, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

117. spacer 5.2|2436543|32|NC_022576|CRISPRCasFinder,CRT matches to NC_025433 (Mycobacteriophage Taj, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

118. spacer 5.20|2437625|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_LT960613 (Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 plasmid P, complete sequence) position: , mismatch: 9, identity: 0.719

tgactcgtcgcgcctatctttttgctttttca	CRISPR spacer
cgtgttaacgagcctttctttttgctttttcc	Protospacer
.*  *.. ** **** ***************

119. spacer 5.23|2436485|32|NC_022576|PILER-CR matches to NZ_CP021405 (Celeribacter manganoxidans strain DY25 plasmid pDY25-A, complete sequence) position: , mismatch: 9, identity: 0.719

tcgatcacgccctcggcggattgctctggtgt	CRISPR spacer
tcgatcacgccatcggcggaatggctggcgat	Protospacer
*********** ******** ** .. *  .*

120. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MF668281 (Mycobacterium phage RitaG, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

121. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MT684597 (Mycobacterium phage Mandlovu, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

122. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KY012363 (Mycobacterium phage Empress, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

123. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MH371123 (Mycobacterium phage Sandalphon, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

124. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MH669010 (Mycobacterium phage PHappiness, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

125. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MN585973 (Mycobacterium phage StAnnes, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

126. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MH077578 (Mycobacterium phage DillTech15, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

127. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MH020235 (Mycobacterium phage Batiatus, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

128. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KY471267 (Mycobacterium phage SassyB, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

129. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KM597530 (Mycobacterium phage Bipolar, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

130. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MN428047 (Mycobacterium phage Doomphist, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

131. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KT281793 (Mycobacterium phage Seagreen, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

132. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MN369755 (Mycobacterium phage Minnie, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

133. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MF668271 (Mycobacterium phage Geralt, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

134. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to NC_041855 (Mycobacterium phage Dorothy, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

135. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KM101124 (Mycobacterium phage Squirty, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

136. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MN735433 (Mycobacterium phage Scottish, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

137. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MG770213 (Mycobacterium phage OldBen, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

138. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to NC_028961 (Mycobacterium phage PopTart, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

139. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to NC_041989 (Mycobacterium phage Shauna1, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

140. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KR997968 (Mycobacterium phage Quico, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

141. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MH669009 (Mycobacterium phage Nimbo, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

142. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MH651178 (Mycobacterium phage KristaRAM, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

143. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MH669001 (Mycobacterium phage EleanorGeorge, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

144. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MK305886 (Mycobacterium phage Poenanya, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

145. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MK016494 (Mycobacterium phage Filuzino, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

146. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KM066034 (Mycobacterium phage Inventum, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

147. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MH632119 (Mycobacterium phage Harley, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

148. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MG925354 (Mycobacterium phage Ogopogo, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

149. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KY702574 (Mycobacterium phage Kingsley, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

150. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to NC_021301 (Mycobacterium phage SiSi, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

151. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MN369752 (Mycobacterium phage Flathead, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

152. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MN310548 (Mycobacterium phage Juice456, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

153. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KR997930 (Mycobacterium phage Florinda, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

154. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to HQ728524 (Mycobacterium phage Wee, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

155. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MH669005 (Mycobacterium phage JoeyJr, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

156. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MK875792 (Mycobacterium phage Polka14, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

157. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KF114874 (Mycobacterium phage Bobi, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

158. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to NC_023728 (Mycobacterium virus DeadP, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

159. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to JN699012 (Mycobacterium phage SG4, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

160. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MN586004 (Mycobacterium phage Strokeseat, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

161. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to KR997931 (Mycobacterium phage Girafales, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

162. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MN204502 (Mycobacterium phage KingMidas, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

163. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MT684601 (Mycobacterium phage Hlubikazi, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

164. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to MT114167 (Mycobacterium phage Phanphagia, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

165. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to NC_022068 (Mycobacteriophage Daenerys, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

166. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to JF937093 (Mycobacterium virus DLane, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

167. spacer 5.24|2436545|32|NC_022576|PILER-CR matches to NC_025433 (Mycobacteriophage Taj, complete genome) position: , mismatch: 9, identity: 0.719

tttttggaagccgcatagtcgcggcacttttt	CRISPR spacer
ccatcctgagccacatagtcgcggcccttttt	Protospacer
.. *.  .****.************ ******

168. spacer 5.42|2437627|32|NC_022576|PILER-CR matches to NZ_LT960613 (Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 plasmid P, complete sequence) position: , mismatch: 9, identity: 0.719

tgactcgtcgcgcctatctttttgctttttca	CRISPR spacer
cgtgttaacgagcctttctttttgctttttcc	Protospacer
.*  *.. ** **** ***************

169. spacer 1.10|883210|34|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NC_023136 (Leisingera methylohalidivorans DSM 14336 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

ctttgtagatcagcgcattctttgcgccgctacg	CRISPR spacer
aggagttgatcagcgcattctttgcgccagccgg	Protospacer
    ** *********************. .  *

170. spacer 2.2|884753|34|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 10, identity: 0.706

ggtagcttcagcagctaccacacccgctcccgca	CRISPR spacer
acttcctccagcagcgaccacacccgctcgacga	Protospacer
. *  **.******* *************    *

171. spacer 2.2|884753|34|NC_022576|PILER-CR,CRISPRCasFinder,CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.706

ggtagcttcagcagctaccacacccgctcccgca	CRISPR spacer
acttcctccagcagcgaccacacccgctcgacga	Protospacer
. *  **.******* *************    *

172. spacer 5.6|2436785|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP022191 (Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

ttctcatcgcgtgcgcagggctgctgctatgg	CRISPR spacer
cgagcatcgcatgcgcggggctgctgcgcggc	Protospacer
.   ******.*****.**********   *

173. spacer 5.19|2437565|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP024166 (Salmonella enterica subsp. enterica serovar Gaminara strain CFSAN070644 plasmid pCFSAN024441_01, complete sequence) position: , mismatch: 10, identity: 0.688

aattctggccattgtgtgttgtttttgcaaat	CRISPR spacer
ttttctggccagtgtgtgtggtttttttcctg	Protospacer
  ********* ******* ****** .

174. spacer 5.19|2437565|32|NC_022576|CRISPRCasFinder,CRT matches to MH572517 (Microviridae sp. isolate SD_HF_67, complete genome) position: , mismatch: 10, identity: 0.688

aattctggccattgtgtgttgtttttgcaaat	CRISPR spacer
cctcaaggccgttgagtgttgtttttgcat--	Protospacer
  *.  ****.*** **************

175. spacer 5.21|2437685|32|NC_022576|CRISPRCasFinder,CRT matches to NZ_CP054029 (Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence) position: , mismatch: 10, identity: 0.688

attgacatgccagccgtaacgcttgctgaatt	CRISPR spacer
cctgacatgccagccgaaaagcttgaaggtgg	Protospacer
 .************** ** *****  *.

176. spacer 5.28|2436787|32|NC_022576|PILER-CR matches to NZ_CP022191 (Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

ttctcatcgcgtgcgcagggctgctgctatgg	CRISPR spacer
cgagcatcgcatgcgcggggctgctgcgcggc	Protospacer
.   ******.*****.**********   *

177. spacer 5.41|2437567|32|NC_022576|PILER-CR matches to NZ_CP024166 (Salmonella enterica subsp. enterica serovar Gaminara strain CFSAN070644 plasmid pCFSAN024441_01, complete sequence) position: , mismatch: 10, identity: 0.688

aattctggccattgtgtgttgtttttgcaaat	CRISPR spacer
ttttctggccagtgtgtgtggtttttttcctg	Protospacer
  ********* ******* ****** .

178. spacer 5.41|2437567|32|NC_022576|PILER-CR matches to MH572517 (Microviridae sp. isolate SD_HF_67, complete genome) position: , mismatch: 10, identity: 0.688

aattctggccattgtgtgttgtttttgcaaat	CRISPR spacer
cctcaaggccgttgagtgttgtttttgcat--	Protospacer
  *.  ****.*** **************

179. spacer 5.43|2437687|32|NC_022576|PILER-CR matches to NZ_CP054029 (Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence) position: , mismatch: 10, identity: 0.688

attgacatgccagccgtaacgcttgctgaatt	CRISPR spacer
cctgacatgccagccgaaaagcttgaaggtgg	Protospacer
 .************** ** *****  *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

27947 : 55860

Mycobacterium_phage(25.0%)

integrase,protease,transposase

attL 32063:32078|attR 53518:53533

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022770988.1\|27947_29303_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_022770989.1\|29392_30622_-	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_022770990.1\|30605_31466_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_022770991.1\|31462_32212_-	di-trans,poly-cis-decaprenylcistransferase	R9W0U9	Flavobacterium_phage	7.1e-17	34.8
32063:32078	attL	NA	NA	NA	NA
WP_041193137.1\|32218_32779_-	ribosome recycling factor	NA	NA	NA	NA
WP_051360395.1\|32816_33581_-	UMP kinase	NA	NA	NA	NA
WP_022770994.1\|33586_34537_-	elongation factor Ts	NA	NA	NA	NA
WP_022770996.1\|34845_35607_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_187292311.1\|35974_36346_+	hypothetical protein	NA	NA	NA	NA
WP_022770999.1\|36342_36792_+	cell division protein ZapA	NA	NA	NA	NA
WP_022771000.1\|37113_37932_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-19	29.9
WP_022771001.1\|37931_38711_+	lipid asymmetry maintenance ABC transporter permease subunit MlaE	NA	NA	NA	NA
WP_022771002.1\|38776_39232_+	outer membrane lipid asymmetry maintenance protein MlaD	NA	NA	NA	NA
WP_022771003.1\|39260_40022_+	VacJ family lipoprotein	NA	NA	NA	NA
WP_022771004.1\|40036_40714_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_022771005.1\|40717_41011_+	STAS domain-containing protein	NA	NA	NA	NA
WP_022771006.1\|41126_41750_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_081699903.1\|41934_42774_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	3.6e-33	38.8
WP_081699763.1\|42907_43198_+	BrnT family toxin	NA	NA	NA	NA
WP_041193646.1\|43175_43424_+	BrnA antitoxin family protein	NA	NA	NA	NA
WP_041193139.1\|43561_44128_+	plasmid pRiA4b ORF-3 family protein	NA	NA	NA	NA
WP_022771010.1\|44327_44930_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-19	45.8
WP_022771011.1\|45033_45939_-	biotin synthesis protein BioC	NA	NA	NA	NA
WP_022771012.1\|45963_46752_+	ComF family protein	NA	NA	NA	NA
WP_151194551.1\|46754_47741_-\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	7.3e-70	46.4
WP_022771014.1\|47828_48515_+	hypothetical protein	NA	NA	NA	NA
WP_022771015.1\|48624_49704_+	50S ribosome-binding GTPase	NA	NA	NA	NA
WP_151194638.1\|50333_50924_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_022771018.1\|51054_51888_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	9.3e-34	38.0
WP_022771020.1\|52214_52703_+\|transposase	transposase	NA	NA	NA	NA
WP_051360252.1\|52766_54104_-\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	9.5e-97	44.6
53518:53533	attR	NA	NA	NA	NA
WP_022771022.1\|54318_55860_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	4.4e-170	60.7

DBSCAN-SWA_2

99027 : 173566

Planktothrix_phage(11.76%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022771077.1\|99027_100941_-\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	1.3e-120	37.4
WP_022771079.1\|101149_102166_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_022771080.1\|102246_102738_-	acetolactate synthase small subunit	NA	NA	NA	NA
WP_022771081.1\|102756_104598_-	acetolactate synthase 3 catalytic subunit	G9E525	Ostreococcus_lucimarinus_virus	1.5e-31	27.3
WP_081699769.1\|104902_106882_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.3e-20	40.2
WP_041193675.1\|106915_107482_+	RNA polymerase sigma factor	NA	NA	NA	NA
WP_022771084.1\|107478_107958_+	DUF3619 family protein	NA	NA	NA	NA
WP_187292313.1\|107968_108880_+	DUF3106 domain-containing protein	NA	NA	NA	NA
WP_022771086.1\|108884_110348_-	argininosuccinate lyase	NA	NA	NA	NA
WP_151194639.1\|110578_113047_+	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_022771088.1\|113162_114098_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	4.0e-78	53.7
WP_022771089.1\|114185_115460_+	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_041193684.1\|115677_117498_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_022771091.1\|117526_118600_+	ABC transporter permease	NA	NA	NA	NA
WP_041193147.1\|118601_119480_+	ABC transporter permease	NA	NA	NA	NA
WP_022771093.1\|119489_120464_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.0e-08	26.9
WP_041193686.1\|120534_121314_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.9e-15	27.6
WP_151194640.1\|121452_122580_-	methyl-accepting chemotaxis protein	NA	NA	NA	NA
WP_022771096.1\|123235_126568_-	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_022771097.1\|126789_127842_+	U32 family peptidase	NA	NA	NA	NA
WP_022771098.1\|127919_128819_+	U32 family peptidase	NA	NA	NA	NA
WP_081699771.1\|128888_129344_+	translesion error-prone DNA polymerase V autoproteolytic subunit	F1C5A6	Cronobacter_phage	6.6e-26	48.3
WP_022771100.1\|129460_130312_-	phosphatidylserine decarboxylase	NA	NA	NA	NA
WP_022771101.1\|130515_131805_-	HDOD domain-containing protein	NA	NA	NA	NA
WP_022771102.1\|131801_133439_-	phosphodiesterase	G3MA91	Bacillus_virus	4.0e-20	33.5
WP_022771103.1\|133529_133784_+	hypothetical protein	NA	NA	NA	NA
WP_051360259.1\|134006_135218_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_022771105.1\|135222_138399_+	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_041193148.1\|138621_139290_+	hypothetical protein	NA	NA	NA	NA
WP_022771108.1\|139418_139733_+	DUF4258 domain-containing protein	NA	NA	NA	NA
WP_022771109.1\|139729_140008_+	YgiT-type zinc finger protein	NA	NA	NA	NA
WP_151194641.1\|140327_141704_+	Eco57I restriction-modification methylase domain-containing protein	A0A2L1IV91	Escherichia_phage	7.5e-182	70.2
WP_022771111.1\|141700_142657_+	type II restriction enzyme	A0A0P0ZG22	Escherichia_phage	2.0e-157	85.4
WP_081699904.1\|143904_144984_+	HD domain-containing protein	NA	NA	NA	NA
WP_022771116.1\|145163_145772_+	GyrI-like domain-containing protein	NA	NA	NA	NA
WP_022771117.1\|146052_146226_+	hypothetical protein	NA	NA	NA	NA
WP_151194554.1\|146500_146722_-	hypothetical protein	NA	NA	NA	NA
WP_022771120.1\|146915_147317_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_022771122.1\|147682_148717_+	hypothetical protein	NA	NA	NA	NA
WP_081699773.1\|148760_151826_+	PAS domain-containing protein	NA	NA	NA	NA
WP_022771124.1\|151819_153016_+	PAS domain S-box protein	NA	NA	NA	NA
WP_051360261.1\|153505_155179_-	diguanylate cyclase	G3MA91	Bacillus_virus	2.4e-20	35.4
WP_022771126.1\|155558_156749_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_022771127.1\|156817_157780_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	A0A1B2LRR6	Wolbachia_phage	2.4e-33	39.4
WP_022771128.1\|158014_158965_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	A0A1B2LRR6	Wolbachia_phage	2.0e-32	38.9
WP_022771129.1\|159151_160045_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_187292343.1\|160133_161222_+	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_022771131.1\|161231_162413_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	9.4e-48	35.4
WP_022771132.1\|162526_162922_+	response regulator	NA	NA	NA	NA
WP_022771133.1\|163074_165408_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.8e-166	42.2
WP_022771134.1\|165537_165891_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.2e-13	40.5
WP_022771135.1\|165971_167456_-	UbiD family decarboxylase	NA	NA	NA	NA
WP_022771136.1\|167492_168089_-	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_022771137.1\|168334_168820_-	SCP2 sterol-binding domain-containing protein	NA	NA	NA	NA
WP_151194555.1\|168965_169874_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_022771139.1\|170094_171114_+	iron ABC transporter permease	NA	NA	NA	NA
WP_022771140.1\|171134_171884_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	1.8e-07	28.0
WP_022771141.1\|171959_173012_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_022771142.1\|173032_173566_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1260731 : 1270878

Acinetobacter_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022772068.1\|1260731_1263326_+	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	4.8e-20	21.5
WP_022772070.1\|1263640_1264648_+	TerC/Alx family metal homeostasis membrane protein	K7QKE8	Escherichia_phage	3.1e-84	52.5
WP_022772071.1\|1264757_1265333_+	TerD family protein	A0A2I7QY15	Vibrio_phage	5.4e-17	31.8
WP_022772072.1\|1265409_1266117_+	TIGR00266 family protein	NA	NA	NA	NA
WP_022772073.1\|1266210_1266792_+	TerD family protein	A0A2L1IWC0	Streptomyces_phage	3.3e-06	29.3
WP_022772074.1\|1266832_1267852_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_022772075.1\|1267848_1269051_+	phosphoribosyltransferase	A0A172Q0Y1	Acinetobacter_phage	1.4e-14	27.0
WP_041193295.1\|1269028_1269787_+	hypothetical protein	NA	NA	NA	NA
WP_022772077.1\|1269783_1270878_+\|protease	cysteine protease StiP family protein	A0A172Q0S8	Acinetobacter_phage	3.1e-37	33.3

DBSCAN-SWA_4

1788526 : 1832114

Streptococcus_phage(16.67%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022773645.1\|1788526_1789234_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_022773649.1\|1789475_1791668_+\|tRNA	methionine--tRNA ligase	NA	NA	NA	NA
WP_187292283.1\|1791741_1793778_-	PAS domain S-box protein	NA	NA	NA	NA
WP_187292284.1\|1793749_1794946_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_022773657.1\|1795128_1796475_-	hypothetical protein	NA	NA	NA	NA
WP_022773661.1\|1796484_1798197_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_022773664.1\|1798396_1799212_+	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_081699843.1\|1799133_1799934_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_041194305.1\|1800036_1800258_+	antitoxin MazE family protein	NA	NA	NA	NA
WP_022773672.1\|1800254_1800578_+	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_081699934.1\|1800554_1801577_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.4e-28	37.2
WP_022773679.1\|1801611_1802511_+\|protease	protease HtpX	NA	NA	NA	NA
WP_022773682.1\|1802652_1803570_-	cation transporter	NA	NA	NA	NA
WP_022773686.1\|1803659_1804172_-	pilin	NA	NA	NA	NA
WP_022773690.1\|1804300_1804573_-	hypothetical protein	NA	NA	NA	NA
WP_022773700.1\|1805073_1805469_+	hypothetical protein	NA	NA	NA	NA
WP_022773704.1\|1805492_1806026_+	hypothetical protein	NA	NA	NA	NA
WP_022773708.1\|1806126_1806828_-	protein phosphatase 2C domain-containing protein	NA	NA	NA	NA
WP_151194603.1\|1807377_1808787_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_041194309.1\|1808942_1809788_-	formylglycine-generating enzyme family protein	A0A7H6	Microcystis_virus	3.0e-32	36.6
WP_022773729.1\|1810306_1810879_-	hypothetical protein	NA	NA	NA	NA
WP_022773732.1\|1810943_1812101_-	J domain-containing protein	NA	NA	NA	NA
WP_022773736.1\|1812107_1813802_-	molecular chaperone HscC	G8DDB7	Micromonas_pusilla_virus	1.7e-79	33.1
WP_022773740.1\|1813785_1814403_-	hypothetical protein	NA	NA	NA	NA
WP_041193392.1\|1814415_1814715_+	hypothetical protein	NA	NA	NA	NA
WP_187292285.1\|1814916_1815309_+\|transposase	transposase	NA	NA	NA	NA
WP_022773751.1\|1815582_1816614_-	hypothetical protein	NA	NA	NA	NA
WP_022773755.1\|1816807_1817860_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_022773758.1\|1817880_1818414_-\|transposase	transposase	NA	NA	NA	NA
WP_022773761.1\|1819434_1822386_+	DNA polymerase I	A0A218MKQ4	uncultured_virus	5.8e-62	30.2
WP_041193395.1\|1822461_1822656_+	hypothetical protein	NA	NA	NA	NA
WP_022773769.1\|1822642_1823065_+	hypothetical protein	NA	NA	NA	NA
WP_022773773.1\|1823141_1824413_+	hypothetical protein	NA	NA	NA	NA
WP_022773777.1\|1824482_1826333_-	VWA domain-containing protein	L7TNG1	Rhizobium_phage	8.7e-08	34.4
WP_022773781.1\|1826329_1829134_-	AAA family ATPase	NA	NA	NA	NA
WP_041194319.1\|1829342_1830533_-\|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_022773788.1\|1830634_1830865_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_022773792.1\|1830861_1831125_+	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_022773796.1\|1831199_1832114_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	A0A1B2LRR6	Wolbachia_phage	6.6e-33	38.9

DBSCAN-SWA_5

2072960 : 2086193

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022774559.1\|2072960_2077181_+	PAS domain S-box protein	A0A1V0SGX0	Hokovirus	2.6e-63	29.1
WP_022774563.1\|2077177_2078353_+	two-component system response regulator	W8CYM9	Bacillus_phage	1.3e-09	32.6
WP_022774567.1\|2078363_2079245_-	hypothetical protein	NA	NA	NA	NA
WP_022774571.1\|2079241_2079991_-	ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	1.7e-10	26.1
WP_041194443.1\|2079995_2081060_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	2.9e-08	27.2
WP_051360350.1\|2081089_2082157_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_022774581.1\|2082132_2083131_-	response regulator	W8CYM9	Bacillus_phage	1.5e-14	39.8
WP_022774585.1\|2083292_2086193_+	response regulator	A0A1V0SGX0	Hokovirus	2.4e-52	33.4

DBSCAN-SWA_6

2451343 : 2461609

Erysipelothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022775645.1\|2451343_2454580_+	DNA/RNA SNF2 family helicase	A0A2K5B253	Erysipelothrix_phage	5.3e-242	43.7
WP_022775648.1\|2454576_2455368_+	DUF4391 domain-containing protein	A0A2K5B2C0	Erysipelothrix_phage	3.0e-05	21.0
WP_022775654.1\|2455609_2457736_+	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	1.5e-96	35.2
WP_051360367.1\|2457738_2458230_+	DUF1016 family protein	NA	NA	NA	NA
WP_081699876.1\|2458198_2458579_+	DUF1016 family protein	A0A0U2BZN7	Salmonella_phage	4.1e-13	38.5
WP_022775658.1\|2458601_2459666_+	DUF1016 family protein	A0A0U2BZN7	Salmonella_phage	6.8e-21	38.0
WP_022775661.1\|2459662_2459902_+	hypothetical protein	NA	NA	NA	NA
WP_022775662.1\|2459904_2460543_+	DUF4433 domain-containing protein	NA	NA	NA	NA
WP_022775665.1\|2460556_2461609_+	macro domain-containing protein	A0A1B2IAE3	Erwinia_phage	1.3e-13	36.2

DBSCAN-SWA_7

2585643 : 2601158

Acinetobacter_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041193548.1\|2585643_2586834_+\|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_081699885.1\|2587037_2587439_-	hypothetical protein	NA	NA	NA	NA
WP_041194649.1\|2587590_2587836_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_041193552.1\|2587832_2588228_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_022776003.1\|2588374_2588908_+\|transposase	transposase	NA	NA	NA	NA
WP_022771141.1\|2588928_2589981_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_187292300.1\|2590084_2590228_-	hypothetical protein	NA	NA	NA	NA
WP_022776012.1\|2590220_2590520_-	BrnA antitoxin family protein	NA	NA	NA	NA
WP_041193553.1\|2590503_2590773_-	BrnT family toxin	NA	NA	NA	NA
WP_022776018.1\|2590948_2591974_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_022776022.1\|2592611_2592830_-	type II toxin-antitoxin system HicB family antitoxin	A0A0D4DCG1	Acinetobacter_phage	2.5e-07	37.7
WP_022776038.1\|2594080_2594527_-	type II toxin-antitoxin system HicB family antitoxin	K7PJX6	Enterobacterial_phage	9.1e-20	40.7
WP_022776042.1\|2594529_2594790_-	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_022776048.1\|2595171_2596050_-	thermonuclease family protein	NA	NA	NA	NA
WP_151194621.1\|2596252_2596528_-	hypothetical protein	NA	NA	NA	NA
WP_022771644.1\|2597275_2598781_+\|transposase	ISNCY-like element ISSymo1 family transposase	NA	NA	NA	NA
WP_187292301.1\|2599746_2600031_+	hypothetical protein	NA	NA	NA	NA
WP_022776073.1\|2600115_2600310_-	hypothetical protein	NA	NA	NA	NA
WP_081699959.1\|2600324_2601158_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	7.1e-34	38.8

DBSCAN-SWA_8

2924811 : 2952479

Acidithiobacillus_phage(33.33%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022776637.1\|2924811_2926152_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.2e-88	50.9
WP_022776638.1\|2926263_2927244_-	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_022776639.1\|2927240_2927705_-	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_022776641.1\|2928059_2928755_+	DNA repair protein RadC	NA	NA	NA	NA
WP_022776642.1\|2928800_2929802_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_022776643.1\|2929798_2931124_+	type 12 methyltransferase	NA	NA	NA	NA
WP_041193610.1\|2931101_2931806_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_022776646.1\|2931939_2932122_-	hypothetical protein	NA	NA	NA	NA
WP_022776647.1\|2932263_2932644_-	type II toxin-antitoxin system death-on-curing family toxin	A0A1B3AYM0	Gordonia_phage	1.4e-08	54.7
WP_022776648.1\|2932647_2932878_-	hypothetical protein	NA	NA	NA	NA
WP_022776650.1\|2933194_2934751_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	2.9e-145	52.3
WP_041194831.1\|2934783_2935539_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	1.7e-71	56.6
WP_022776654.1\|2936222_2937587_-\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_022776655.1\|2937701_2938097_-	hypothetical protein	NA	NA	NA	NA
WP_022776656.1\|2938080_2938371_-	hypothetical protein	NA	NA	NA	NA
WP_022776658.1\|2938690_2939671_-	ThiF family adenylyltransferase	NA	NA	NA	NA
WP_041193614.1\|2939654_2940437_-	hypothetical protein	NA	NA	NA	NA
WP_022776660.1\|2940517_2941285_-	hypothetical protein	NA	NA	NA	NA
WP_022776661.1\|2941359_2942607_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A0S1WEW6	Vibrio_phage	3.4e-24	29.7
WP_187292308.1\|2942692_2942893_-	hypothetical protein	NA	NA	NA	NA
WP_151194635.1\|2943149_2943365_-	hypothetical protein	NA	NA	NA	NA
WP_022776664.1\|2943365_2944418_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_022776665.1\|2944438_2944972_-\|transposase	transposase	NA	NA	NA	NA
WP_022776667.1\|2945494_2946634_+	DNA integrity scanning protein DisA nucleotide-binding domain protein	NA	NA	NA	NA
WP_187292309.1\|2946734_2951129_+	hypothetical protein	NA	NA	NA	NA
WP_022776669.1\|2951153_2952479_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	4.3e-25	29.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022576

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection