CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022582	Streptococcus sp. I-P16, complete sequence	1 crisprs	cas3,csm6,WYL,DinG,csa3,DEDDh	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_022582_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022582_1

1981190-1981281

Orphan

Consensus_repeat	Method
GTTGAAGTTGTAGTCGGTTCTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022582_1

>merge|NC_022582|1|1981190-1981281|CRISPRCasFinder
GTTGAAGTTGTAGTCGGTTCTTCGCTTGTCGTTGTTGTAGTGGTTGTAGCTTCTTTGGTTGTGGTCGTAGTTGAAGTTGTAGTCGGTTCTTC

>NC_022582|1|1|1981190-1981281|CRISPRCasFinder
GTTGAAGTTGTAGTCGGTTCTTC	GCTTGTCGTTGTTGTAGTGGTTGTAGCTTCTTTGGTTGTGGTCGTA
GTTGAAGTTGTAGTCGGTTCTTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022582.1\|WP_023024970.1\|1987765_1989976_+\|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|236436
NC_022582.1\|WP_023024960.1\|1979618_1979960_-\|hypothetical-protein	unknown	unknown	unknown
NC_022582.1\|WP_003013825.1\|1975443_1976238_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226953
NC_022582.1\|WP_001265622.1\|1974027_1974177_+\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|179075
NC_022582.1\|WP_023024968.1\|1985858_1987640_+\|heme-transporter-CcmD	unknown	unknown	gnl\|CDD\|227904
NC_022582.1\|WP_001253404.1\|1979281_1979605_-\|two-pore-domain-potassium-channel-family-protein	unknown	unknown	gnl\|CDD\|369572
NC_022582.1\|WP_023024974.1\|1990677_1991274_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl\|CDD\|379137
NC_022582.1\|WP_023024978.1\|1993013_1994297_+\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240542
NC_022582.1\|WP_023024966.1\|1984240_1985515_+\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234586
NC_022582.1\|WP_004240734.1\|1979884_1980187_-\|DUF1211-domain-containing-protein	unknown	unknown	gnl\|CDD\|377696
NC_022582.1\|WP_023024976.1\|1991468_1992953_+\|threonine-synthase	unknown	unknown	gnl\|CDD\|236418
NC_022582.1\|WP_003010127.1\|1977213_1977417_-\|hypothetical-protein	unknown	unknown	unknown
NC_022582.1\|WP_023024972.1\|1990172_1990673_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|226489
NC_022582.1\|WP_003010129.1\|1976234_1977221_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213234
NC_022582.1\|WP_003009516.1\|1973829_1974012_+\|50S-ribosomal-protein-L32	unknown	unknown	gnl\|CDD\|234901
NC_022582.1\|WP_023024958.1\|1978235_1979285_-\|TIGR00341-family-protein	unknown	unknown	gnl\|CDD\|377221
NC_022582.1\|WP_042507491.1\|1995274_1995700_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NC_022582.1\|WP_023024980.1\|1994302_1994926_+\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|319825
NC_022582.1\|WP_023024964.1\|1983057_1984050_+\|aspartate--ammonia-ligase	unknown	unknown	gnl\|CDD\|225304
NC_022582.1\|WP_003013947.1\|1974656_1975442_-\|multidrug-transporter	unknown	unknown	gnl\|CDD\|226218

Protein	Function_ID	Function_description	E-value
NC_022582.1\|WP_023024970.1\|1987765_1989976_+\|anaerobic-ribonucleoside-triphosphate-reductase	gnl\|CDD\|236436	PRK09263, PRK09263, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
NC_022582.1\|WP_042507491.1\|1995274_1995700_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	7.02054e-14
NC_022582.1\|WP_003013825.1\|1975443_1976238_-\|ABC-transporter-permease	gnl\|CDD\|226953	COG4587, COG4587, ABC-type uncharacterized transport system, permease component [General function prediction only].	1.8501e-24
NC_022582.1\|WP_001265622.1\|1974027_1974177_+\|50S-ribosomal-protein-L33	gnl\|CDD\|179075	PRK00595, rpmG, 50S ribosomal protein L33; Validated.	6.45602e-18
NC_022582.1\|WP_023024968.1\|1985858_1987640_+\|heme-transporter-CcmD	gnl\|CDD\|227904	COG5617, COG5617, Predicted integral membrane protein [Function unknown].	5.32083e-06
NC_022582.1\|WP_001253404.1\|1979281_1979605_-\|two-pore-domain-potassium-channel-family-protein	gnl\|CDD\|369572	pfam07885, Ion_trans_2, Ion channel. This family includes the two membrane helix type ion channels found in bacteria.	1.56146e-07
NC_022582.1\|WP_023024974.1\|1990677_1991274_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl\|CDD\|379137	pfam13353, Fer4_12, 4Fe-4S single cluster domain. This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.	5.64151e-78
NC_022582.1\|WP_023024978.1\|1993013_1994297_+\|MATE-family-efflux-transporter	gnl\|CDD\|240542	cd13137, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	6.16791e-85
NC_022582.1\|WP_023024966.1\|1984240_1985515_+\|histidine--tRNA-ligase	gnl\|CDD\|234586	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed.	0
NC_022582.1\|WP_004240734.1\|1979884_1980187_-\|DUF1211-domain-containing-protein	gnl\|CDD\|377696	pfam06736, DUF1211, Protein of unknown function (DUF1211). This family represents a conserved region within a number of hypothetical proteins of unknown function found in eukaryotes, bacteria and archaea. These may possibly be integral membrane proteins.	9.36755e-20
NC_022582.1\|WP_023024976.1\|1991468_1992953_+\|threonine-synthase	gnl\|CDD\|236418	PRK09225, PRK09225, threonine synthase; Validated.	0
NC_022582.1\|WP_023024972.1\|1990172_1990673_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|226489	COG3981, COG3981, Predicted acetyltransferase [General function prediction only].	1.44888e-72
NC_022582.1\|WP_003010129.1\|1976234_1977221_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213234	cd03267, ABC_NatA_like, ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA. NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.	5.0332e-92
NC_022582.1\|WP_003009516.1\|1973829_1974012_+\|50S-ribosomal-protein-L32	gnl\|CDD\|234901	PRK01110, rpmF, 50S ribosomal protein L32; Validated.	1.12173e-17
NC_022582.1\|WP_023024958.1\|1978235_1979285_-\|TIGR00341-family-protein	gnl\|CDD\|377221	pfam04087, DUF389, Domain of unknown function (DUF389). Family of hypothetical bacterial proteins with an undetermined function.	1.4609e-52
NC_022582.1\|WP_023024980.1\|1994302_1994926_+\|HAD-IA-family-hydrolase	gnl\|CDD\|319825	cd07523, HAD_YsbA-like, uncharacterized family of the haloacid dehalogenase-like superfamily, similar to the uncharacterized Lactococcus lactis YsbA. The specific function of Lactococcus lactis YsbA is unknown. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.84253e-64
NC_022582.1\|WP_023024964.1\|1983057_1984050_+\|aspartate--ammonia-ligase	gnl\|CDD\|225304	COG2502, AsnA, Asparagine synthetase A [Amino acid transport and metabolism].	0
NC_022582.1\|WP_003013947.1\|1974656_1975442_-\|multidrug-transporter	gnl\|CDD\|226218	COG3694, COG3694, ABC-type uncharacterized transport system, permease component [General function prediction only].	1.95355e-32

>NC_022582.1|WP_004240734.1|1979884_1980187_-|DUF1211-domain-containing-protein
MKKDRLIVLTDAVLAIIMTILILELEKPTTPSLEAFWDLRQNFFACFLSFFWLGSLWMALNTLWEKVEKISSEIIWWNLFLLLERQEFSLENFMPSKIPV
>NC_022582.1|WP_023024960.1|1979618_1979960_-|hypothetical-protein
MEFVSTLGAAGVLFGEFHAIQDTSLNDVVDRIYINVKDLPFQSLGALANILSDVKKGLIKDSHIWSFFQSFFKQYQLIISLNQIYQFVYLSLMEIMSYLHFDYWKKRLGQELV
>NC_022582.1|WP_001253404.1|1979281_1979605_-|two-pore-domain-potassium-channel-family-protein
MRRLKMLWHIIQVTGFTRFALSFVTFVFGSGGVLFLVEPAITNYGDGLWYAFVTSTTVGYGDLLAVTLIGRITSVFLTIYGLIFFGCLSAVIINYYTDLNKERGEDK
>NC_022582.1|WP_023024958.1|1978235_1979285_-|TIGR00341-family-protein
MTANYSTREYREKLYDDLHVRLRDTAILMCAIFIASIGLNMNSTAVVIGAMLISPLMTPIVGLGFGLAIFDTRLIKQSLEVLLTQVLVSLLVSTLYFWISPLSYASSELIARTSPTIWDVLIAIAGGIAGFIGSRKKEANNIVPGVAIATALMPPICTAGYGLANGNVRFLFGALYLFLINCVFIMLANIVGTRILMRKSPLTSFKELSIKMRIGLISLIVLLILPASYSAVTLTIEQARNEGIKQFVGKEFANYTVINQVYKSSNNELVLTVVGDPISEEELETLHQKQASYGIQSVQLKVNQVQNSPTLDSEATKEFYENIDKYIDQKLSEKDSQNDLVKENEADKD
>NC_022582.1|WP_003010127.1|1977213_1977417_-|hypothetical-protein
MDIKETFNQLDNTKFNDFNNRLEGFEKLFKDKYYFTHPEDFSSIFSILVKYGKSTSKYILSKGEIYE
>NC_022582.1|WP_003010129.1|1976234_1977221_-|ATP-binding-cassette-domain-containing-protein
MSEIVINAQNLSKNFYNFDSRLPFIKRFLKRNQITIRAVQDISFTIKRGSIVGFIGSNGAGKSTTIKMLTGTLYPSSGKLEVNGEIPFKRSINFRKKISIVVGNKLQLFQDVSAMDYFQLIGTLYEVEPAILQERIQELSNLLNVKDQLYQQVRTLSLGQKMKMEFIAASLTSPEILFLDEPTIGLDIQSKKDIRTFLKKMNEECHTTIILTSHDMDDISSVCDELIVIDKGKIILQESMDVILSKFSDFKYLKIKMTLDLVPELCSVKGVVVISQTKSECILKIPRDFVFETLESINKLVDIEDFEISNLSLEEIILQNYFTKKEHN
>NC_022582.1|WP_003013825.1|1975443_1976238_-|ABC-transporter-permease
MKKEMSIILISFRSILNYKSSVLLLMLQASIQIMISVFLWTYIYQSNQINIAGYDFTSMVQYYLGTIIFSYFVFYPVDWEINDDVHSGNFFSILIKPVTFYKYYFCKMLGDRLAHLLFIIIPVILFSSVYYKNELLTIEILILGSIAIILSMVLWFLISCCVGMLSFWLENIFFVLTVKEIVIQFLSGILLPLSFFSNNFRLFLDVLPFKYLVYEPLQMFSNDTYKLIDYLRIICIQLIWCIIFYIISRFILRKGVEHFSNVGG
>NC_022582.1|WP_003013947.1|1974656_1975442_-|multidrug-transporter
MFRIKVIFRLLHFGFKSDMNFHFDFFCGLFSSILWIGLPIVFFRLIFLNIDSFNGWDYYQILFLVGSYTIVDGVMMGLLIRSMGILESDILSGNLDQILLRPFDTQLFYIFRSFNLVQFVNTFFGLAIIFISYGNLNVHLNSLKILFYILSLMCGCIIYYSIWFLITISSFWFPTKFSKVDVFLNYIGISKYPYNIFTGINRLITMLFVPNLLIANPAVLIFLGKDTLNLFFYQIVFTVFLIIISRTIFRKGLKKYESAGR
>NC_022582.1|WP_001265622.1|1974027_1974177_+|50S-ribosomal-protein-L33
MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVVFTEVK
>NC_022582.1|WP_003009516.1|1973829_1974012_+|50S-ribosomal-protein-L32
MAVPARRTSKAKKNKRRTHYKVTAPSVNFDEATGDYSRSHRVSLKGYYKGRKIAKAASAE
>NC_022582.1|WP_023024964.1|1983057_1984050_+|aspartate--ammonia-ligase
MKKSFIHQQEEISFVKTTFTQYLKDKLEVVEVQGPILSKVGDGMQDNLSGVENPVSVKVLQIPNETYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPDEDSLDATHSVYVDQWDWEKVIPNGNRNLAYLKETVEKIYKAIRLTELAVEARYDIESILPKQITFIHTEELVERYPELTPKERENAITKEYGAVFLIGIGGVLSDGKPHDGRAPDYDDWTTETENGYKGLNGDILVWNDNLGAAFELSSMGIRVDEDTLKRQVAITGDQDRLELEWHRALLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVREQYENIL
>NC_022582.1|WP_023024966.1|1984240_1985515_+|histidine--tRNA-ligase
MKLQKPKGTQDILPQESAKWQYVEGFARETFKKYNYAEIRTPIFEHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQKPSKVYYIGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMADQFFKEIGIENVVLHLNTLGSTASRTAYRQALIDYLLPMKDQLSKDSQRRLEENPLRVLDSKEKEDKQAVENAPSILDYLDEESQAHFDAVRAMLDGLGIAYVIDTNMVRGLDYYNHTIFEFVTEVDGNELTVCAGGRYDGLVEYFGGPATPGFGFGMGLERLLLILDKQGVELPVEASLDVYVAVLGSEAEVASLELVQALRRQGFIAERDYLGRKLKAQFKSADVFGAKTIIALGGSEVESGQITVKNNQTRQEVTTSIEEVKNDFQTILNQL
>NC_022582.1|WP_023024968.1|1985858_1987640_+|heme-transporter-CcmD
MSEKEKESHKLGLSVGSNFQDTQELRKVLEQSISREEEVLTASQPVESDQNQEESQVNGEGVETEASTETLSRLSRSGHSRKEKLEARSRDQEDVEESLENQEDEKPLGRYAIKRPVPLSLPIALSVLLGMVHVALPFINLVATNQQTQDLYAGWAISQGQVPYGHFFGVNGLLYYGLSGLGSLVGGQVLLVAFQILAYFFAGTSLYRMVRSLVASEKIAGQVQLLFYLLAGVLGFGGNYAVFYALPFLFGSMNFILAYLEGEKTDESFVAYGAGACLAFMIVPWLSVIFYLLAFLGLTAYHVKQKKLAHGFYQFLAALLGFSLVFYPLGYITVWNGSFGYAIHQTLYSLRSLQFDAGHLFANLVYYCLLLLTLGFASAFVMSFRKVSTSGQRVIRFMSWFGLLLVVAVVVGTPEQGAYQFLSLLPFGLPLLALWFAGDESTYQRRKMKNNSIWDLYFSSQAFLPILAMAYLVGYPVVNQLVLQSNLASDRSAIAQYIKSHSDSKDTIYAWDQTAHLYQESGRLAASALLTPTAYMGPKENRTNLINQIKQAKPKFIVVNKDLDVTSALQKVLTKNYEKVNQKGSQYTLYRYK
>NC_022582.1|WP_023024970.1|1987765_1989976_+|anaerobic-ribonucleoside-triphosphate-reductase
MITLREEHIQSLPQLFVEKRDGRKVKFDVDKIYRALVKATEEVTGLTPALEAKLETVTDRIVAEVLERFPRGVKIYEIQNVVEHELLQANEYAIAESYITYRTQRDFERSKATDINFTIGKLLNKDQAVVNENANKDSDVFNTQRDLTAGIVGKSIGLKMLPKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFEGMLKNGFKIGNAEVESPKSIQTATAQISQIIANVASSQYGGCSADRIDEVLAPYAEKNYKKHLKDAEEWVLPEKREDYAWQKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTNRFEREIQKAILEIRIKGLGSEHRTAIFPKLIFTLKRGLNLEPGSPNYDIKQLALECATKRMYPDVLSYDKIVELTGSFKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESGGDKEKFWEIFNERMNIAEDALVYRVERTKEATPANAPILYQYGAFGKRLGKYDQVDQLFRNRRATISLGYIGLYEVATVFYGPNWEENPEAKQFTIEIIKDMKKRVEEWSDQYDYHFSIYSTPSESLTDRFCRLDTEKFGKVPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGATGGFIHYCEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFAPTERGFTCPNCGNSDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKSAGHQVKD
>NC_022582.1|WP_023024972.1|1990172_1990673_+|GNAT-family-N-acetyltransferase
MELRRPTLADKETVLDMMTEFEETQSAHDGGFWDAEAFVYEDWLKSNRDMEMGLGIPDGWVPAVQLVAFARDGQAVGFLNLRLRLSDYLLEEGGHIGYSIRPSEQGKGYAKEALRQGLQVAKEKNIHLALVTCSIDNPASRAVILANGGQLEDVRNGTERYWIEVE
>NC_022582.1|WP_023024974.1|1990677_1991274_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MTWNTPKPGEWKSEELSQGRIIDYKAFNFVDGEGVRNSIYVAGCMFHCEGCYNVATWSFNAGIPYTKELEEQIMEDLAQPYVQGLTLLGGEPFLNTGILLPLVKRVKRELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDKSKRNLMLQFRGSSNQRIIDVQQSLKEGKVVIWDKLNDGKESYEQVKRE
>NC_022582.1|WP_023024976.1|1991468_1992953_+|threonine-synthase
MTLVYQSTRDAKNTVTASQAILQGLATDGGLFTPVSYPKVDLDFDILKDASYQEVAKLVLSAFLDDFTAEELDYCITNAYDSKFDTPAIAPLVKLDGQYNLELFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGTEIIVFYPKDGVSKVQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLAANKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIKAGDKVNFTVPTGNFGNILAAFYAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIFHLLGNDAVKTAELMSALNTQGQYELTDFDAEIFDLFAAEYATEAETAAEIKRVYESDSYIEDPHTAVASAVFKKYQEATGDAAKTVIASTASPYKFPVVAVEAVTGKSGLSDFEALAQLHEISGVALPPAVDGLETAPVRHKTTVAAAEMQSAVETYLGL
>NC_022582.1|WP_023024978.1|1993013_1994297_+|MATE-family-efflux-transporter
MSRQQQVDRQILRIALPAIGENFLQMLMGMVDSYLVAQLGLVAVSGVSVAGNIITIYQAIFIALGAAVVSLLSKSMGQKDQKAIAHQATESIKVTVLLSLVLGALSLCFSKELIALLGVEAAVAEAGGIYLSLVGGSILLLGLMTTFGALVRVAHNPRTPMYVSLLTNVLNALLSSILIFVFGLGIAGAALGTVLSRLLGTYLLWRQVQLPFAPFCWGLDRDLLSLALPAAGERLMMRAGDIVIIAMVAVFGTRAVAGNAIGEVLTQFNYMPAFGIATATVMLVAKSLGQNDWQGIKQITSRSFWLSFLSMFPLALTIFLFGNPLTALYTKDPGALVASLSVILFSLLGTPLTAGTVIYTAVWQGLGNARLPFYATTIGMWVIRIGSGYLMGVVLGWGLPGIWAGTLLDNGFRWFFLKTLYHRKWKE
>NC_022582.1|WP_023024980.1|1994302_1994926_+|HAD-IA-family-hydrolase
MTRAFIWDLDGTLLDSYEAILDGIAETYAHYSLDFDREVVYAFILKQSVQALLEEVARDHDLDAEEMNRYRTSSLREKNAQVHLMPGARDILAWAKEEGIVQFVYTHKGKNAYPILEDLGILSYFQEVVTTDNGFRRKPDPEGVDYLVDKYQLDRNETYYIGDRTLDVDLADNAGIGSINFLDYKPDVNHTIHRLDEIRLYFKQEKS
>NC_022582.1|WP_042507491.1|1995274_1995700_+|winged-helix-turn-helix-transcriptional-regulator
MAEMHDLLYRLKLADQSSTQLFEKQLGISLTRYQMLQFLLAEAPCSQAALQEKLAIDPAALTRHFKVLEAGGYVTRSRNPENQREVVVELKELARDRLLVHPPAHHLQVKTQMDQILSEQERNQLNDLLEKLVSGLEQMTL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

86677 : 148768

Staphylococcus_phage(16.67%)

bacteriocin,protease,tRNA,integrase

attL 80077:80092|attR 116270:116285

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
80077:80092	attL	NA	NA	NA	NA
WP_023022110.1\|86677_87817_+\|integrase	site-specific integrase	Q9AZR0	Lactococcus_phage	1.2e-39	30.9
WP_023022111.1\|88238_89510_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	2.8e-98	46.8
WP_023022112.1\|89624_90095_+	DUF3013 family protein	NA	NA	NA	NA
WP_023022113.1\|90140_92447_+	exonuclease SbcC	NA	NA	NA	NA
WP_042507493.1\|93128_94148_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_023022116.1\|94165_95116_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_023022117.1\|95117_95867_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_023022118.1\|95907_98367_-	bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase	NA	NA	NA	NA
WP_023022119.1\|98365_98551_+	hypothetical protein	NA	NA	NA	NA
WP_006595074.1\|98628_100848_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	5.0e-10	36.5
WP_023022120.1\|101100_101544_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_023022121.1\|101566_102220_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_023022122.1\|102360_103386_+	DUF3114 domain-containing protein	NA	NA	NA	NA
WP_009732121.1\|103495_103990_-	thiol peroxidase	NA	NA	NA	NA
WP_023022123.1\|104077_105010_-	metal ABC transporter substrate-binding lipoprotein/fibrin-binding adhesin FimA	NA	NA	NA	NA
WP_023022124.1\|105021_105864_-	metal ABC transporter permease	NA	NA	NA	NA
WP_023022125.1\|105860_106583_-	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.6e-18	29.7
WP_023022126.1\|106731_108627_+	endopeptidase	E3T4I7	Cafeteria_roenbergensis_virus	1.0e-72	30.2
WP_023022128.1\|108887_109664_-	glycyl-radical enzyme activating protein	NA	NA	NA	NA
WP_023022129.1\|109793_110537_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_023022130.1\|110551_111523_+	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_006595062.1\|111690_112014_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_006595061.1\|112024_112336_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_006595060.1\|112347_113649_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_006596971.1\|113790_116229_+	glycyl radical protein	Q66LZ4	Escherichia_phage	9.4e-10	56.6
WP_006595058.1\|116244_116913_+	fructose-6-phosphate aldolase	M4QRR4	Synechococcus_phage	2.0e-23	31.5
116270:116285	attR	NA	NA	NA	NA
WP_006596970.1\|116927_118019_+	glycerol dehydrogenase	NA	NA	NA	NA
WP_006595056.1\|118230_118371_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_006595055.1\|118465_119140_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_006595054.1\|119482_121465_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_023022131.1\|121747_124249_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	66.3
WP_023022132.1\|124450_124609_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_023022134.1\|124823_125012_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_023022135.1\|125179_125872_+	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_023022136.1\|125999_127403_+	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_042507495.1\|127616_128540_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_023022138.1\|128728_129658_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.1e-22	31.2
WP_023022139.1\|129650_130529_+	ABC transporter permease	NA	NA	NA	NA
WP_023022140.1\|130855_132667_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	2.4e-95	37.9
WP_023022141.1\|132912_134688_+	PTS mannitol transporter subunit IICBA	NA	NA	NA	NA
WP_042361355.1\|134705_136661_+	transcription antiterminator	NA	NA	NA	NA
WP_023022143.1\|136662_137100_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_023022144.1\|137161_138298_+	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_023022145.1\|139698_140520_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_023022146.1\|140843_141845_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_023022147.1\|141862_142063_+	hypothetical protein	NA	NA	NA	NA
WP_023022148.1\|142162_143164_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_023022149.1\|143191_144070_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_006595038.1\|144136_144829_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_006595037.1\|144832_145519_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_006595036.1\|145538_146303_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.8e-37	41.6
WP_023022150.1\|146662_148768_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	7.4e-120	38.6

DBSCAN-SWA_2

349481 : 356321

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023022402.1\|349481_350702_+	DNA cytosine methyltransferase	V5URQ5	Oenococcus_phage	3.4e-133	59.2
WP_023022404.1\|350779_352369_+	hypothetical protein	V5US45	Oenococcus_phage	4.2e-19	27.9
WP_023022408.1\|352675_353047_-	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	2.4e-13	40.2
WP_023022410.1\|353043_354456_-	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	8.9e-178	66.3
WP_023022412.1\|354458_355136_-	helix-turn-helix transcriptional regulator	A0A1B0RXB1	Streptococcus_phage	2.8e-52	48.2
WP_042507436.1\|355318_355858_+	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_023022416.1\|355847_356321_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.7e-14	27.8

DBSCAN-SWA_3

1110354 : 1122204

Staphylococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023023704.1\|1110354_1111887_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.3e-19	33.3
WP_023023706.1\|1112024_1113080_-	BMP family ABC transporter substrate-binding protein	A0A0A7DN02	Lactobacillus_phage	1.3e-51	36.4
WP_023023709.1\|1113158_1113548_-	cytidine deaminase	NA	NA	NA	NA
WP_023023711.1\|1113534_1114197_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_023023714.1\|1114220_1115498_-	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	4.8e-114	52.2
WP_042507472.1\|1115494_1116088_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_023023718.1\|1116183_1117104_+	type I pantothenate kinase	A0A1B1ISL9	uncultured_Mediterranean_phage	1.9e-35	35.3
WP_023023719.1\|1117209_1117458_+	30S ribosomal protein S20	NA	NA	NA	NA
WP_023023721.1\|1117523_1118054_+	DNA topology modulation protein	A0A097BYE2	Leuconostoc_phage	1.3e-25	39.9
WP_023023723.1\|1118078_1118657_-	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	2.2e-18	49.1
WP_023023725.1\|1118784_1119627_+	DegV family protein	A0A1X9I5J4	Streptococcus_phage	1.2e-100	66.9
WP_023023727.1\|1119824_1121471_-	hypothetical protein	NA	NA	NA	NA
WP_023023729.1\|1121460_1122204_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.9e-26	27.6

DBSCAN-SWA_4

1301544 : 1313542

Streptococcus_phage(64.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023024013.1\|1301544_1302537_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.8e-15	30.2
WP_023024015.1\|1303084_1303909_+	peptidylprolyl isomerase	A0A1V0S9I2	Catovirus	4.9e-19	36.6
WP_023024017.1\|1304092_1305634_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	7.4e-53	27.5
WP_023024018.1\|1305863_1306217_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.0e-34	59.0
WP_023024020.1\|1306226_1306715_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	3.2e-34	44.6
WP_023024022.1\|1306707_1307280_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	3.7e-58	57.8
WP_023024024.1\|1307269_1308154_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	5.8e-111	70.8
WP_023024026.1\|1308156_1308477_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.8e-30	65.1
WP_023024028.1\|1308481_1309381_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.5e-79	52.0
WP_023024030.1\|1309377_1310016_-	dTMP kinase	M1PSC7	Streptococcus_phage	3.9e-72	63.6
WP_023024032.1\|1310188_1311076_+	YitT family protein	M1Q1P6	Streptococcus_phage	1.1e-80	51.2
WP_023024035.1\|1311115_1311772_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	3.5e-84	75.5
WP_003008277.1\|1312067_1312778_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.3e-17	28.1
WP_023024036.1\|1312777_1313542_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.8e-15	25.7

DBSCAN-SWA_5

1863610 : 1871612

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023024785.1\|1863610_1864453_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	1.3e-14	29.0
WP_023024787.1\|1864437_1865265_-	energy-coupling factor transporter ATPase	G3M9Y6	Bacillus_virus	4.7e-22	36.1
WP_023024788.1\|1865265_1865805_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_023024790.1\|1865901_1867188_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	2.8e-05	30.3
WP_023024792.1\|1867184_1868435_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.6e-101	46.6
WP_023024793.1\|1868587_1868959_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	5.6e-15	56.6
WP_023024795.1\|1868960_1870049_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_042507536.1\|1870130_1871612_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	8.9e-96	40.5

DBSCAN-SWA_6

1914347 : 1922357

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023024858.1\|1914347_1914593_+	acyl carrier protein	E3SMK8	Prochlorococcus_phage	1.2e-05	37.3
WP_023024860.1\|1914762_1915470_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D8KNF0	Synechococcus_phage	3.9e-41	39.7
WP_023024862.1\|1915538_1919264_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	2.7e-32	25.5
WP_023024864.1\|1919276_1920716_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.0e-51	33.6
WP_023024866.1\|1920780_1921803_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	2.8e-64	44.0
WP_023024867.1\|1921802_1922357_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage