CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022584	Streptococcus sp. I-G2, complete genome	4 crisprs	cas1,cas2,csn2,csm6,DinG,csa3,DEDDh,cas3	0	16	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_022584_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022584_1

231990-232204

Orphan

Consensus_repeat	Method
TCCGGGGGACCTTTTTAAC	CRT

4 spacers

The CRISPR arrays of NC_022584_1

>merge|NC_022584|1|231990-232204|CRT
TCCGGGGGACCTTTTTAACCCGAGCCGAGAAACTCGGAAGCGAGGAAGATCCGGGGGACCTTTTTAACGGTCGCCTAGAAATAAAAAAGCGACCCAGGTCCGGGGGACCTTTTTAACCCGAGCCGAGAAACTCGGAAGCGAGGAAGATCCGGGGGACCTTTTTAACGGTCGCCTAGAAATAAAAAAGCGACCCAGGTCCGGGGGACCTTTTTAAC

>NC_022584|1|1|231990-232204|CRT
TCCGGGGGACCTTTTTAAC	CCGAGCCGAGAAACTCGGAAGCGAGGAAGA
TCCGGGGGACCTTTTTAAC	GGTCGCCTAGAAATAAAAAAGCGACCCAGG
TCCGGGGGACCTTTTTAAC	CCGAGCCGAGAAACTCGGAAGCGAGGAAGA
TCCGGGGGACCTTTTTAAC	GGTCGCCTAGAAATAAAAAAGCGACCCAGG
TCCGGGGGACCTTTTTAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022584.1\|WP_023022812.1\|245858_247133_+\|DUF2130-domain-containing-protein	unknown	unknown	gnl\|CDD\|370744
NC_022584.1\|WP_023022798.1\|233531_234332_+\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_023022808.1\|241822_243016_-\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NC_022584.1\|WP_023022783.1\|225602_226571_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223566
NC_022584.1\|WP_023022796.1\|232814_233522_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NC_022584.1\|WP_023026648.1\|227724_228036_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373958
NC_022584.1\|WP_023026653.1\|243201_245487_+\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NC_022584.1\|WP_023026650.1\|235261_238363_+\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|180917
NC_022584.1\|WP_023026645.1\|224266_225187_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|224398
NC_022584.1\|WP_023026652.1\|241172_241730_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NC_022584.1\|WP_023022776.1\|222399_223296_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|235450
NC_022584.1\|WP_023026649.1\|229081_230869_+\|DNA-primase	unknown	unknown	gnl\|CDD\|235551
NC_022584.1\|WP_023022794.1\|230871_231984_+\|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl\|CDD\|236413
NC_022584.1\|WP_023022790.1\|228460_228841_-\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|224881
NC_022584.1\|WP_006596590.1\|232329_232659_+\|metal-sulfur-cluster-assembly-factor	unknown	unknown	gnl\|CDD\|225062
NC_022584.1\|WP_023026651.1\|238448_239462_+\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NC_022584.1\|WP_023022804.1\|239522_241028_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NC_022584.1\|WP_023026644.1\|223292_224270_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NC_022584.1\|WP_023026647.1\|226775_227645_+\|aquaporin-family-protein	unknown	unknown	gnl\|CDD\|223653
NC_022584.1\|WP_000048054.1\|228182_228359_+\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707

Protein	Function_ID	Function_description	E-value
NC_022584.1\|WP_023022812.1\|245858_247133_+\|DUF2130-domain-containing-protein	gnl\|CDD\|370744	pfam09903, DUF2130, Uncharacterized protein conserved in bacteria (DUF2130). This domain, found in various hypothetical prokaryotic proteins, has no known function.	1.00956e-91
NC_022584.1\|WP_023022808.1\|241822_243016_-\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	1.3921e-101
NC_022584.1\|WP_023022783.1\|225602_226571_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	5.6315e-82
NC_022584.1\|WP_023022796.1\|232814_233522_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.79517e-61
NC_022584.1\|WP_023026648.1\|227724_228036_+\|hypothetical-protein	gnl\|CDD\|373958	pfam15592, Imm41, Immunity protein 41. A predicted immunity protein with an alpha+beta fold and a conserved SF motif and tryptophan residue. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Ntox21, Ntox29 or Tox-ART-RSE-like ADP-ribosyltransferase families.	0.00824172
NC_022584.1\|WP_023026653.1\|243201_245487_+\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_022584.1\|WP_023026650.1\|235261_238363_+\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|180917	PRK07279, dnaE, DNA polymerase III DnaE; Reviewed.	0
NC_022584.1\|WP_023026645.1\|224266_225187_+\|DNA-binding-protein-WhiA	gnl\|CDD\|224398	COG1481, COG1481, Uncharacterized protein conserved in bacteria [Function unknown].	3.1025e-120
NC_022584.1\|WP_023026652.1\|241172_241730_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.02452e-27
NC_022584.1\|WP_023022776.1\|222399_223296_+\|RNase-adapter-RapZ	gnl\|CDD\|235450	PRK05416, PRK05416, RNase adapter RapZ.	4.02455e-172
NC_022584.1\|WP_023026649.1\|229081_230869_+\|DNA-primase	gnl\|CDD\|235551	PRK05667, dnaG, DNA primase; Validated.	0
NC_022584.1\|WP_023022794.1\|230871_231984_+\|RNA-polymerase-sigma-factor-RpoD	gnl\|CDD\|236413	PRK09210, PRK09210, RNA polymerase sigma factor RpoD; Validated.	0
NC_022584.1\|WP_023022790.1\|228460_228841_-\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|224881	COG1970, MscL, Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	9.92903e-46
NC_022584.1\|WP_006596590.1\|232329_232659_+\|metal-sulfur-cluster-assembly-factor	gnl\|CDD\|225062	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only].	1.17337e-42
NC_022584.1\|WP_023026651.1\|238448_239462_+\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NC_022584.1\|WP_023022804.1\|239522_241028_+\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NC_022584.1\|WP_023026644.1\|223292_224270_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	8.88293e-148
NC_022584.1\|WP_023026647.1\|226775_227645_+\|aquaporin-family-protein	gnl\|CDD\|223653	COG0580, GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism].	3.58881e-69
NC_022584.1\|WP_000048054.1\|228182_228359_+\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.11448e-10

>NC_022584.1|WP_023022794.1|230871_231984_+|RNA-polymerase-sigma-factor-RpoD
MAKEQKDITTLDVQIAEFIRSHKKSGTATDDEINDQLVIPFALDADGIDDLLQRIQDAGISITDKEGNPSARVLNNEEEEPELTDEELLGSNSAKVNDPVRMYLKEIGVVPLLTNEEEQELAILVEQGDLEAKQRLAEANLRLVVSIAKRYVGRGMQFLDLIQEGNMGLMKAVDKFDYTKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLGDFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGKVFNVTRERIRQIEAKALRKLRHPSRSKPLRDFIED
>NC_022584.1|WP_023026649.1|229081_230869_+|DNA-primase
MVDKQLISEIKNSVNIVDVIGEVVQLTKAGRNFLGLCPFHGEKTPSFNVVEDKQFYHCFGCGKSGDVFKFIEDYRGVSFMEAVQIVGDQVGIQVQALAPSQSRGQQTDGKQPFYEIHQEAAKFYHAILMTTKMGEDARQYLYDRGLDDEVLRHFQIGLAPAEGNYLYQSVSGKFSENIMAESGLFHISDMGTMYDAFQDRIMFPLSDDTGRVIAFSGRLWRDQAEGTKPQGKYKNSRSTLLFNKSYELYHLDKAKQVAKKNHELYLMEGFMDVIAAYRAGIENAVASMGTALTREHVAHLSKFTKKVILAYDGDKAGRLATAKALEVLEKQEVEVVQIPDQMDPDEYLKKNSPQALADLLEKTRLSRVEFLMDYWKPDNIENLQAQIEFVEKMAPLIAQTPSVTAQNTYIYKLADLLVDFDYLQVEQTVNASRLQMRSQRQDQGPIQTQAPVASPTVVQKQLPRLVRAENHLLHRMNAFPYVLNEYRLRTDFSFDTPALQTLYQLLCQNGEVTSQDLSEQTEEVQRAWYLMLEENLPDEIAENELEEVEETRNRELLRKESQQIGKKVREASHSGDADQALLELERLIAQKRRME
>NC_022584.1|WP_023022790.1|228460_228841_-|large-conductance-mechanosensitive-channel-protein-MscL
MLKELKAFLLRGNVVDLAVAVIIGAAFGAIVTSFVNDIITPLILNPALEAAHVKNIAELTWNGVAYGSFLSAVINFLVIGTVLFFVVKAAEKAQNLGKKEEAAEEEVAGPTQEELLAEIRDLLANK
>NC_022584.1|WP_000048054.1|228182_228359_+|30S-ribosomal-protein-S21
MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVKRKRKSEAARKRKKF
>NC_022584.1|WP_023026648.1|227724_228036_+|hypothetical-protein
MKEKNLIEDNRRADHFSFLYYLHEKKVFHSESLAALCQYLVALESVSIEQLRDLRWIENQILRHLVYHFDENDLSKISNLPMNYWEELEAFEQVISNLYDRYE
>NC_022584.1|WP_023026647.1|226775_227645_+|aquaporin-family-protein
MQFDFWVKVATEFIATALLIILGNGAVANVELKGTKGHQSGWLVIAIGYGIGVMMPALMFGNVSGNHINPAFTIGLAVSGLFPWENVLYYIVAQILGAMFGQLVVVATHRPYYLQTENPNNILGTFSTISSLDKGTPESRKAATINGFVNEFAGSFVLFFGALALTKHFFGAEVASLAQRAATEQGGIFDASSTAAKLALSQAHAPGLGVAHLALGFLVMALVTSLGGPTGPGLNPARDLGPRLVHAFLPKSVLGEHKGDSKWWYAWVPVVAPILAAIVAIALFSFLYL
>NC_022584.1|WP_023022783.1|225602_226571_-|NAD(P)/FAD-dependent-oxidoreductase
MSEIYDITIIGGGPVGLFAAFYGHLRQVKVKLIDSLPQLGGQPAILYPEKTILDVPGFTNLTGEELSKRLINQLNTFETEICLNETVLDIHKNEDHFLIETNKDQHFSRAVIIAMGGGAFKPRPLEVDGAEEFENVHYHVSNIQQYTGKQVAILGGGDSAVDWALAFEKIAPTTLVHRRDNFRALEHSVEELKASSVSIQTPYVPSRLIGENGRASHLEITKVKSDETQLVPIDELFVNYGFKSSVGKLKEWGLDLQRHKILVNRKQETSREGIYACGDCCFYDGKIDLIATGLGEAPTAVNNAINYIYPDKKVQPVHSTSL
>NC_022584.1|WP_023026645.1|224266_225187_+|DNA-binding-protein-WhiA
MSFTIKVKEELLTLHRFEKSELSALIKMSGSLGLSMGGLSLSLTTENAKIARHIYELIVEFYQVKSDIRHHQKTNLKKNRVYTVSIDEKVEDILADLHLADSFFGIETGIDPRILEEDEASRAYLRGAFLASGTIKDPESGRYQLEISSVYSDHAQDLANLMQHFLLDAKTIERKKGVVTYLQRAEDIIDFLILVEAKQALEEFESVKVMREARNDLNRANNAEMANIARTVTASMKTINNIVKIMDTIGLGGLPVELQEVAYVRIQNPDYSIQQIADALKTPLTKSGVNHRLRKINKIAEELDNL
>NC_022584.1|WP_023026644.1|223292_224270_+|YvcK-family-protein
MRKPKMTVIGGGTGISVILNSLRKKDVEITAIVTVADDGGSSGELRKNIHQLTPPGDLRNVLVAMSDMPRFYEKVFQYRFAEDDGPLAGHPLGNLIIAGISEMQGSTYNAMQLLTKFFHTTGKIYPSSDTPLTLHAVFMDGSEVAGESEIAHHEGMIDYVYVTNTYNDETPKASRKVVDAILESDMVILGPGSLFTSILPNLMIEEIGQALLDTKAEVAYVCNIMTQRGETEHFTDSDHVSVLHKHLKKPFIDTVLVNIEKVPQEYMDTNRFDEYLVQVEHDFAGLKSQVPRVISTNFLRLENGGAFHDGEAVVDELMQMVQVIK
>NC_022584.1|WP_023022776.1|222399_223296_+|RNase-adapter-RapZ
MTDTEKTIQLVIVTGMSGAGKTVAIQSFEDMGYFTIDNMPPALLPKFIELIQLSMDNNKLALVVDMRSRSFFAEIRSILDELENHEGIDFKILFLDATDSELVARYKETRRSHPLAADGRVLDGITLERELLAPLKNMSQNVIDTTELTPRNLRKVIAEQFSRQDSQPEFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQPELRNQTGLDDDVYNYVMDHKESEEFYRHLYELIAPILPAYKREGKSVLTIAMGCTGGQHRSVAFAARLGRDLAKDWTVNMSHRDKDRRKETVNRS
>NC_022584.1|WP_006596590.1|232329_232659_+|metal-sulfur-cluster-assembly-factor
MSYTTEEIEQIKNRILENLEQVIDPELGIDIVNLGLVYEIRFDGETGETEIDMTLTTMGCPLADLLTDQIYDALTGMEEVTKVDVKLVWYPAWTVEKMSRYARIALGIK
>NC_022584.1|WP_023022796.1|232814_233522_+|ABC-transporter-ATP-binding-protein
MNQYPLVYLDHVQKVYGKHIALGDVSVNIQPGRIIGLLGPNGSGKTTIIKLVNGLLQPTSGNVYIHGQVPSAKTKQVVSYLPDTTYLDENMKISETIRFFQDFYKDFNAQRAYQLLNDLHLHPEQKLKQLSKGNKEKVQLILVMSREADLYILDEPIGGVDPAARDYILRTIIQNRRPNSSVLISTHLIADVEQVLDEALFINQGRILLHENTTVLRNQYGKSIDEIFREQFRMY
>NC_022584.1|WP_023022798.1|233531_234332_+|hypothetical-protein
MFGKLMKYELKATYKWYLIISGVLAILSIFAGLLASSVITGASTFTENTALTIGSIVVLVIFAGYIGLTLTNYIIIIRRFYNNIFGREGYLTWTLPTGSHTVLLVKVTSALIWSIFCFISLILSLLIFLGVIGLAQQQNIFDLLGPLFEKIGSSLIWQSLLFQVLATISGILMLYCAISLGQLFINSRIVMAFVFGFILWVVLSIIGRLFPSISISELSRTATMSSDTLSDILVVNFIPAYIYEVVKIVAMYFTVHYVTKFKLNLQ
>NC_022584.1|WP_023026650.1|235261_238363_+|DNA-polymerase-III-subunit-alpha
MITQLDTKSVYTFMDSLVSIRDYIHRAKEMGYQQIGLMDIDNLYGAYEFLEECQKAGMGAVLGLDLEVEIPVGPLSIRLVALGTKGYKHLIKISSMKMMGTTDWSAFQHLLDDIAIIVPYFEGIEYLDLGQDFAIGVFPDTPAKHFSRPVFPLHTVRYFSTSDLESLQMLHAIRNNCSLKEVGAIDTSMMFLSPEELERAFSHNFPDSIPYLEKTLAAVHYEIDTQLKLPRFNPEKPAVEELRELAEEGLRAKGLNQAVYQERLRHELAVIHQMGFDDYFLIVWDLLRFGRSQGYYMGMGRGSAVGSLVAYALDITGIDPVKNNLLFERFLNLERYTMPDIDIDIPDVYRPKFIQYVKNRYRSPHVAQIVTFSTFGAKQAIRDVFKRFGTPEYELTNLTKRIGLRDTLSSAYEKNLAFRQAIQSRPEYRKGFEIAKRIEGQPRQTSIHAAGVVMSGEDLTNQIPIKMGEEMNLTQYDAHGVEANGLLKMDFLGLRNLTFAQRMQEAVKEKYQKDIKIEDIPLEDPETIALFAAGNTKGIFQFEQAGAIRLLRRVQPSCFEEIVATTSLNRPGASDYIDNFVKRKHGKEKVDMIDPSLEEILAPTYGIMLYQEQVMQVAQTFAGFSLGKADILRRAMGKKNVAEMHRMEDDFIKGAIALGHSAEKAKQVFSIMEKFAGYGFNRSHAYAYSALAFQLAYFKVHYPDVFFDIMLNYSSSDYLTDALQFNFQVAPLTINTIPYKDKFQDQKIYLGMKNIKGLPKDLAFWIIDQRPFESIEDFILRLPSQYHKLPLLTPLVELGLFDCFEKNRRKVLQNLPNLFVFADELGSLFGEANYSWMDAEDYSKAEKYEMEQRVIGVGLSPHPLVEILAASSQPVRPIASLSEGEQATILVELQSIRTIRTKNGENMAFLQVSDLQKKMDVTLFPETYRQYSSKIREKGYYYLKGKIQSRDGRLQMILMEAEEATNQRFWIQLFDHQEDRAVLDILKAYPGPYPVVIRYEEEKKTIQLKGVSVQKNEKLENELASIAMKTIYR
>NC_022584.1|WP_023026651.1|238448_239462_+|6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYNGYAGMVAGDIHQLDASSVGDIISRGGTMLHSARYPEFAEREGQLKGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGLPGTIDNDIVGTDFTIGFDTAVTTVMDAIDKIRDTSSSHHRTFVIEVMGRHAGDIALWSGIASGADEIIIPEEGFAIEDVVESIKKGYEKGRTHNIIVLAEGVMSAAEFGKALKDAGDTSDLRVTELGHIQRGGSPTARDRVLASRLGAHAVKLLKAGIGGVAVGIRNEQMVENPILGSAEEGALFSLTEDGKIKVNNPHKADLNLAELNRSLSSI
>NC_022584.1|WP_023022804.1|239522_241028_+|pyruvate-kinase
MNKRVKIVATLGPAVEIRGGKKFGDDGYWGEKLDVEASAQNIAQLIEAGANTFRFNFSHGDHQEQGDRMATVKRAEEIAGKKVGFLLDTKGPEIRTELFEGDAKEYSYKTGEKIRVATKQGIKSTREVIALNVAGGLDIYDDVEVGHQVLVDDGKLGLRIFAKDDDTREFEVVVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQTLLNEYGRLNSDTFERNSKTEVMASAVKDATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTDAPSSTDDMFEIAERKAVEAGLVQSGDDIVIVAGVPLGEAVRTNTMRIRTVR
>NC_022584.1|WP_023026652.1|241172_241730_+|signal-peptidase-I
MSKRDLIRNIIIIGILGLVLITLRLFVFQPLWVSDQMANASVKKDDLVLATKKGKIDRTDLVLYHVKEKQYLGRVIAIESDEVSYVDDVFYLNGVATAEPYLDKMKTKHLAAPSGDYFTNDFFSRELKGTKAGKVPSNSYLVLNDDRNNTKDSREFGYIKASQIEGVVDFRLYPLNKFGFIKIEE
>NC_022584.1|WP_023022808.1|241822_243016_-|cation-diffusion-facilitator-family-transporter
MNQSQSNLKLAERGALISIVAYLILSAAKLATGHLLHSSSLVADGFNNLSDIISNVALLIGIRMARQPADRDHRFGHWKIEDLASLVTSIIMFYVGFDVLRDTVQKILSRETSVIDPLGAIVGVGSALVMFAVYLYNRTLAKKAQSKALNAAAKDNLSDVVTSLGTSVAIGASALNYPIVDQLVAIVITFFILKTAYDIFIESSFSLSDGFDESLLDKYKAAILELPKVSRVKSQRGRTYGSNIYLDVVIEMNPDLSVYESHAITEEVERLLKEEFGVFDIDVHVEPSSIPEDEILDNVLLKLKTYEERLQAQQEYSTLLADNFTLIDEFGQESHKEDLVRLQEEHQIPFKNFEIESISQKTKLIRYELNNQIHTSLWRRHEHWQKVFHQITSKKEN
>NC_022584.1|WP_023026653.1|243201_245487_+|DNA-helicase-PcrA
MNPLLKGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKMVNPWNILAITFTNKAAREMKERAYQLNPATQDCLIATFHSMCVRILRRDADHIGYNRNFTIVDPGEQRTLMKRILKSLNLDPKKWNERTILGTISNAKNDLIDEVAYAAQAGDMYTQIVAKCYEAYQKELRQSEAVDFDDLIMLTLRLFDQHPDVLTYYQQKFQYIHVDEYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVLLEENYRSTKTILQAANDVIKNNRNRRPKNLWTQNADGEEIVYYRANDEQDEAVFVAKTIEELSRKAGYKHRDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIAYLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFAQMQGSSLLDASANIMLSGIKGKAAQAIWDFANLILDLREKLDQLTITELVEEVLDKTGYMTALANQGNLESQARIENIQEFLSVTKNFDENGESVEDESGVDTLSRFLNDLALIADTDDGAQETSEVTLMTLHAAKGLEFPVVFLIGMEENVFPLSRAAEDPDELEEERRLAYVGITRAEKILFLTNANSRLLFGRTSYNRPTRFINEISSDLLTYQGLARPANTSFKASYSNGGGTTFGKGMSLSQALQERKRQAAPSALTSSSLPFGNSSQAGAKESVAWSIGDIAVHKKWGEGTVLEVSGSGNTQELKINFPEVGLKKLLASVAPIEKK
>NC_022584.1|WP_023022812.1|245858_247133_+|DUF2130-domain-containing-protein
MNEIKCPNCGEVFTVNESQYSELLSQVRTAEFDKEIHERIRQELALAEQKALNEQQEKLAKKDQEIAQLQNQIQQFDTEKELAKKEVEQTASQSLLEKEKEVQALENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLTSVKQNYEAQLKAANEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKISARGSKGDFIFRDFDENGLEFISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLVSMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALIREQNIDITHFEEDLDAFKVAFAKNYNSASVNFGKAIDEIDKAIKRMEEVKKFLTTSENQLRLANNKLDDVSVKKLTRKNPTMKAKFDALKED

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Crispr_ID: NC_022584_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022584_2

378085-379637

TypeII

Consensus_repeat	Method
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CRISPRCasFinder
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CRT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	PILER-CR

23 spacers

csn2,cas2,cas1,cas9,csm6

The CRISPR arrays of NC_022584_2

>merge|NC_022584|2|378085-379637|CRISPRCasFinder,CRT,PILER-CR
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACTTTGTCATATTTCCCAGTTTAGAACCTGTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACCCTTGCGACTGTAGGAGACGACCAGCCTTTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACTAAAAATCAATTCTTTTAGATCATCACTCAGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACCGTAGCGGACAGCTTCCGATTATTGGAATTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACTGAATTTATCGGTGACCGTGTGTTGATATAGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACATGAGGAAAGATGAATGAAAATCACACAAGGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACTATGCTTGAACTTGCTAAGGCCTACAAGCTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACAGAGGGTATTTTTGGCAGAATTATAAATCTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACCGAAAGGGCAAAGAATGAATTGATGCGATTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACGGGTCTTTATGATAGTATCCATGGTCTGGAGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACGAACCTGGACGATGGTGTCTTTGTTGATAAGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACATATCGTCCATGTCTGGGATAGGCCCGCTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACCAACACTGACGTACTGTCCAGCCGATATCTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACTCATAAATTATCAAATTGAACTTCTCTTACTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACACGTTGTTTCTCACCACGTTTCGAACCTTTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACAAGCTACTGCGATATTAAAGACTGGAATGTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACGAAAGCGTCTCAGGACGCTTAAACGACTTGGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACTAACGTATAGCGGAGGTTGAAGGCAAGCTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACTTTAACGTAGCTGAAAGCGGATGGGAAAGCGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACCTAAAGGCTTCGGAGACTTTGAAGCATCACTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACAGGACGCAAGCTACACGTATCTCCAGAGTTGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACTTTACAGCCGGACAAGAAATTAAGGCCGGAGTTTTTGTACTCTCAAGATTTAAGTAACTGTACAACTCGCATAGACAATATAACGAGTACTGTCGAGTTTCTGTACTCTCAAGATTTAAGTAAGTGTACAAC

>NC_022584|2|1|378085-379637|CRISPRCasFinder
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TTTGTCATATTTCCCAGTTTAGAACCTGT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CCTTGCGACTGTAGGAGACGACCAGCCTTT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TAAAAATCAATTCTTTTAGATCATCACTCA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CGTAGCGGACAGCTTCCGATTATTGGAATT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TGAATTTATCGGTGACCGTGTGTTGATATA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	ATGAGGAAAGATGAATGAAAATCACACAAG
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TATGCTTGAACTTGCTAAGGCCTACAAGCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	AGAGGGTATTTTTGGCAGAATTATAAATCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CGAAAGGGCAAAGAATGAATTGATGCGATT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	GGGTCTTTATGATAGTATCCATGGTCTGGA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	GAACCTGGACGATGGTGTCTTTGTTGATAA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	ATATCGTCCATGTCTGGGATAGGCCCGCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CAACACTGACGTACTGTCCAGCCGATATCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TCATAAATTATCAAATTGAACTTCTCTTACT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	ACGTTGTTTCTCACCACGTTTCGAACCTTT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	AAGCTACTGCGATATTAAAGACTGGAATGT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	GAAAGCGTCTCAGGACGCTTAAACGACTTG
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TAACGTATAGCGGAGGTTGAAGGCAAGCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TTTAACGTAGCTGAAAGCGGATGGGAAAGC
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CTAAAGGCTTCGGAGACTTTGAAGCATCACT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	AGGACGCAAGCTACACGTATCTCCAGAGTT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TTTACAGCCGGACAAGAAATTAAGGCCGGA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TCGCATAGACAATATAACGAGTACTGTCGA
GTTTCTGTACTCTCAAGATTTAAGTAAGTGTACAAC

>NC_022584|2|2|378085-379637|CRT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TTTGTCATATTTCCCAGTTTAGAACCTGT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CCTTGCGACTGTAGGAGACGACCAGCCTTT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TAAAAATCAATTCTTTTAGATCATCACTCA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CGTAGCGGACAGCTTCCGATTATTGGAATT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TGAATTTATCGGTGACCGTGTGTTGATATA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	ATGAGGAAAGATGAATGAAAATCACACAAG
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TATGCTTGAACTTGCTAAGGCCTACAAGCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	AGAGGGTATTTTTGGCAGAATTATAAATCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CGAAAGGGCAAAGAATGAATTGATGCGATT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	GGGTCTTTATGATAGTATCCATGGTCTGGA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	GAACCTGGACGATGGTGTCTTTGTTGATAA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	ATATCGTCCATGTCTGGGATAGGCCCGCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CAACACTGACGTACTGTCCAGCCGATATCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TCATAAATTATCAAATTGAACTTCTCTTACT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	ACGTTGTTTCTCACCACGTTTCGAACCTTT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	AAGCTACTGCGATATTAAAGACTGGAATGT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	GAAAGCGTCTCAGGACGCTTAAACGACTTG
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TAACGTATAGCGGAGGTTGAAGGCAAGCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TTTAACGTAGCTGAAAGCGGATGGGAAAGC
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CTAAAGGCTTCGGAGACTTTGAAGCATCACT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	AGGACGCAAGCTACACGTATCTCCAGAGTT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TTTACAGCCGGACAAGAAATTAAGGCCGGA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TCGCATAGACAATATAACGAGTACTGTCGA
GTTTCTGTACTCTCAAGATTTAAGTAAGTGTACAAC

>NC_022584|2|1|378941-379637|PILER-CR
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TCATAAATTATCAAATTGAACTTCTCTTACT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	ACGTTGTTTCTCACCACGTTTCGAACCTTT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	AAGCTACTGCGATATTAAAGACTGGAATGT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	GAAAGCGTCTCAGGACGCTTAAACGACTTG
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TAACGTATAGCGGAGGTTGAAGGCAAGCT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TTTAACGTAGCTGAAAGCGGATGGGAAAGC
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	CTAAAGGCTTCGGAGACTTTGAAGCATCACT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	AGGACGCAAGCTACACGTATCTCCAGAGTT
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TTTACAGCCGGACAAGAAATTAAGGCCGGA
GTTTTTGTACTCTCAAGATTTAAGTAACTGTACAAC	TCGCATAGACAATATAACGAGTACTGTCGA
GTTTCTGTACTCTCAAGATTTAAGTAAGTGTACAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022584.1\|WP_003016415.1\|376649_376973_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NC_022584.1\|WP_023026756.1\|383455_384667_+\|phosphopentomutase	unknown	unknown	gnl\|CDD\|235430
NC_022584.1\|WP_023026754.1\|381155_382529_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NC_022584.1\|WP_023026744.1\|366878_367871_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370676
NC_022584.1\|WP_023026757.1\|385224_386034_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|236183
NC_022584.1\|WP_023026747.1\|369732_370014_+\|chorismate-mutase	unknown	unknown	gnl\|CDD\|168880
NC_022584.1\|WP_023023068.1\|384668_385211_+\|DUF1697-domain-containing-protein	unknown	unknown	gnl\|CDD\|226319
NC_022584.1\|WP_042361071.1\|370015_371227_+\|voltage-gated-chloride-channel-protein	unknown	unknown	gnl\|CDD\|239654
NC_022584.1\|WP_023026746.1\|369169_369613_+\|flavodoxin	unknown	unknown	gnl\|CDD\|180922
NC_022584.1\|WP_042361398.1\|387660_388371_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NC_022584.1\|WP_023023082.1\|389943_390852_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_022584.1\|WP_023026755.1\|382691_383390_+\|ribose-5-phosphate-isomerase-RpiA	unknown	unknown	gnl\|CDD\|234816
NC_022584.1\|WP_023023078.1\|388370_389129_+\|hypothetical-protein	csm6	cd09746_csm6_CAS-III-A	gnl\|CDD\|312974
NC_022584.1\|WP_003016418.1\|371344_371692_+\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NC_022584.1\|WP_023026749.1\|372172_375556_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|273840
NC_022584.1\|WP_023026751.1\|376969_378013_+\|CRISPR-associated-protein-Cas7	csn2	cd12217_csn2_CAS-II-A	gnl\|CDD\|213410
NC_022584.1\|WP_023026753.1\|380299_381112_+\|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|225217
NC_022584.1\|WP_023026745.1\|368053_368992_-\|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA	unknown	unknown	gnl\|CDD\|223691
NC_022584.1\|WP_023023080.1\|389139_389871_+\|NAD-dependent-protein-deacylase	unknown	unknown	gnl\|CDD\|234777
NC_022584.1\|WP_042361074.1\|375736_376645_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694

Protein	Function_ID	Function_description	E-value
NC_022584.1\|WP_003016415.1\|376649_376973_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.51916e-28
NC_022584.1\|WP_023026756.1\|383455_384667_+\|phosphopentomutase	gnl\|CDD\|235430	PRK05362, PRK05362, phosphopentomutase; Provisional.	0
NC_022584.1\|WP_023026754.1\|381155_382529_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NC_022584.1\|WP_023026744.1\|366878_367871_-\|hypothetical-protein	gnl\|CDD\|370676	pfam09770, PAT1, Topoisomerase II-associated protein PAT1. Members of this family are necessary for accurate chromosome transmission during cell division.	8.94075e-13
NC_022584.1\|WP_023026757.1\|385224_386034_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|236183	PRK08202, PRK08202, purine nucleoside phosphorylase; Provisional.	1.75638e-165
NC_022584.1\|WP_023026747.1\|369732_370014_+\|chorismate-mutase	gnl\|CDD\|168880	PRK07248, PRK07248, chorismate mutase.	5.59433e-32
NC_022584.1\|WP_023023068.1\|384668_385211_+\|DUF1697-domain-containing-protein	gnl\|CDD\|226319	COG3797, COG3797, Uncharacterized protein conserved in bacteria [Function unknown].	5.26306e-52
NC_022584.1\|WP_042361071.1\|370015_371227_+\|voltage-gated-chloride-channel-protein	gnl\|CDD\|239654	cd03682, ClC_sycA_like, ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation competitiveness, and N2 fixation on Phaseolus vulgaris plants, due to its reduced ability for acid resistance. This family is part of the ClC chloride channel superfamiy. These proteins catalyse the selective flow of Cl- ions across cell membranes and Cl-/H+ exchange transport. These proteins share two characteristics that are apparently inherent to the entire ClC chloride channel superfamily: a unique double-barreled architecture and voltage-dependent gating mechanism. The gating is conferred by the permeating anion itself, acting as the gating charge.	2.12643e-146
NC_022584.1\|WP_023026746.1\|369169_369613_+\|flavodoxin	gnl\|CDD\|180922	PRK07308, PRK07308, flavodoxin; Validated.	1.48435e-78
NC_022584.1\|WP_042361398.1\|387660_388371_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.91549e-152
NC_022584.1\|WP_023023082.1\|389943_390852_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.59372e-35
NC_022584.1\|WP_023026755.1\|382691_383390_+\|ribose-5-phosphate-isomerase-RpiA	gnl\|CDD\|234816	PRK00702, PRK00702, ribose-5-phosphate isomerase RpiA.	3.01783e-116
NC_022584.1\|WP_023023078.1\|388370_389129_+\|hypothetical-protein	gnl\|CDD\|312974	pfam09659, Cas_Csm6, CRISPR-associated protein (Cas_Csm6). Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.61724e-18
NC_022584.1\|WP_003016418.1\|371344_371692_+\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	4.66603e-69
NC_022584.1\|WP_023026749.1\|372172_375556_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|273840	TIGR01865, conserved_hypothetical_protein, CRISPR subtype II/NMENI RNA-guided endonuclease Cas9/Csn1. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein found only in CRISPR-containing species, near other CRISPR-associated proteins (cas), as part of the NMENI subtype of CRISPR/Cas locus. The species range so far for this protein is animal pathogens and commensals only.	0
NC_022584.1\|WP_023026751.1\|376969_378013_+\|CRISPR-associated-protein-Cas7	gnl\|CDD\|213410	cd12217, Stu0660_Csn2, Stu0660-like CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. This family of Csn2 proteins includes Stu0660, the proteins are larger than other (canonical) Csn2 proteins as they have an additional alpha-helical C-terminal domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	2.20874e-139
NC_022584.1\|WP_023026753.1\|380299_381112_+\|PrsW-family-intramembrane-metalloprotease	gnl\|CDD\|225217	COG2339, prsW, Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones].	1.8378e-22
NC_022584.1\|WP_023026745.1\|368053_368992_-\|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	7.68573e-101
NC_022584.1\|WP_023023080.1\|389139_389871_+\|NAD-dependent-protein-deacylase	gnl\|CDD\|234777	PRK00481, PRK00481, NAD-dependent deacetylase; Provisional.	1.35661e-115
NC_022584.1\|WP_042361074.1\|375736_376645_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.21064e-123

>NC_022584.1|WP_023026751.1|376969_378013_+|CRISPR-associated-protein-Cas7
MKMNISHPYKDNITLSFGQFTQVVGQDQQLKYYIWQILLWYFGGKKYSEEDLVLFEQNEPKILIDDTVVSRSEFRVIQLSNINDLIEQMEYKKGTIAYDYLKKKINTVETMEQIENINDHLDRISLLLNQNLNLQLDGINYHTEAKYFNADQLIQKNFLPYFGQNDKNISFEFVDNKTKFLLFLSMLQVVITDQSEKVLLVLRNMDDYLSYKEFVECCEQLERLTNYCNMLYTISFPSNEGYLHVTKEVLEEINIVSDYIDHFYSLEFMYERFTDQYPINQIPSKQEFLSSLRKIGPYLFSSDILHMSLSIEDQVALRILNNLYQYEMKIKFHIEPVNPMLLKYLEE
>NC_022584.1|WP_003016415.1|376649_376973_+|CRISPR-associated-endonuclease-Cas2
MRYEALRLLCFFDLPMDTNQEKRIYRNFRKDLIANGFEMLQFSVYYRTCPNRSFASKFYKKLSQSNLPSGNVRLLAVTEKQFSEMVLIIGGKTKQEEVVSDNKLVVI
>NC_022584.1|WP_042361074.1|375736_376645_+|type-II-CRISPR-associated-endonuclease-Cas1
MTWRIVHVCQSEKMQLKLDNLLIKKMGEDYIIPLSDISIIVAEGGETVVTLRLLSALSKYNIALIVCDNEHLPTGIYHSQNGHFRAYKKLQEQLLWTQEQKDKIWQIVTYFKINNQQDVLSMFEKNIDCIQLLADYKDHIEFGDKTNREGHAAKVYFNELFGKKFVRLTQQETDVINAGLNYGYAIMRAQMARIIAGYGLNPLIGIFHKNEYNQFNLVDDLMEPFRQIIDVWVYQNLRDEEYLKYEFRLALTDTLNAKIRYGKETCSVTVAMDKYVKGFLKCISDKDTSKFYCPIVSSVEWS
>NC_022584.1|WP_023026749.1|372172_375556_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNGLVLGLDIGIASVGVGILEKDSGKIIHANSRIFPAATADNNVERRTSRQARRLNRRKKHRSVRLHDLFEEYGLLTDFSKVSINLNPYQIRVQGLDKRLTNEELFIALKNIVKRRGISYLDDASEDGGAVSSDYGKAVEENRKLLAQQTPGQIQLDRFEKYGQVRGDFTVVENGEKRRLINVFSTSAYRKEAERILRKQQEFNNKITEGFIEDYLTILTGKRKYYHGPGNEKSRTDYGRYTTKKDSQGEYITLDNIFGILIGKCTFYPDEYRASKASYTAQEFNLLNDLNNLTVPTETKKLSVEQKKTIVEYAKTAKTLGASTLLKYIAKLIGVSVDQIHGYRIDPNEKPEMHTFEVYRKMQSLETIRVEELPRKVIDELAHILTLNTEREGIEEAINAKLKDIFSQDQVLELVQFRKNNSSLFSKGWHNFSLKLMMELIPELYETSEEQMTILTRLGKQKSKETSKRTKYIDEKELTEEIYNPVVAKSVRQAIKIINEATKRYGIFDNIVIEMARENNEEDAKKEYIKRQKANLDEKNAAMEKAAFQYNGKKELPDNVFHGHKELATKIRLWHQQGEKCLYTGKNIPISDLIQNRYKYEIDHILPLSLSFDDSLSNKVLVLATANQEKGQRTPFQALDSMDYAWSYREFKSYVKDSKLLSNKKKDYLLTEEDISKIEVKQKFIERNLVDTRYSSRVVLNALQDFYKEHQFDTTISVVRGQFTSQLRRKWGIEKSRETYHHHAVDALIIAASSQLRLWKKHNNPLISYKEEQFVDSETGEIISMSDDEYKELVFKAPYDHFVDTLKSKKFEDSILFSYQVDSKYNRKISDATIYATRKAKLDKDKSEETYVLGKIKDIYSQAGYDTFIKIYNKDKSRFLMYHKDPQTFEKVIEEILRTYPSKELNEKNKEVPCNPFEKYRQENGPIRKYSRKGNGPEIKSLKYYDNKLGNHIDITPNESMNQVVLQSLKPWRTDVFFNHQTEKYELMGLKYSDLNFEKGSGKYSISLEKYNSIKMNEGVSEESEFKFTLYKNDLILIKDALTKEAQIFRYGSRNDTSKHYVELKPYDMSKFEGDERLIKVLGTVAKGGRCIKGLNKKDISIFKVKTDVLGNKHFIKKEGEEPKLKF
>NC_022584.1|WP_003016418.1|371344_371692_+|50S-ribosomal-protein-L19
MNPLIQSLTEGQLRTDIPAFRPGDTVRVHAKVVEGTRERIQIFEGVVIARKGQGHTEMYTVRKISNGVGVERTFPVHTPRVEKIEVVRYGKVRRAKLYYLRALQGKAARIKEIRR
>NC_022584.1|WP_042361071.1|370015_371227_+|voltage-gated-chloride-channel-protein
MTISKRTLVYTLDAIIIGGIVGVIDTLFGRVLIGIGEVRTDYLLYLLPFLPLAGILITYLNRTYGGKSQKGMELLFEVGEGREKAIPKRLIPLTILSTWLTHLFGGSAGREGVAVQLGGTVAHALRRDWLGPHASRIYLVTGMAAGFGGLFQTPLAAIFFAMEVLVVGRLEWRALYPAAIAAFVASWTSHTLGLEKFTQIISAKLSLSPQVFLQLLLLGVIFGLTGKLFAYLLGTFKQSFTRAFSNPYVRIGVVGLGLSILLYLIGAGRYTGLGTNLISQSFEGADGKGLITGADWILKLLFTVSTIAAGYKGGEVTPLFSIGASLGVWLAPFFGLPVYLVAALGYAAVFAGATSTTIGPILIGCEVFGFQHWPAFLLVCLVATRLFPALSIYGGQKVAKKLQ
>NC_022584.1|WP_023026747.1|369732_370014_+|chorismate-mutase
MELEKIRQEIDSIDKELVHLLERRMHCVEDIIRYKETHQNPILDRAREDEVLANVAGLVQDKRYEETILATYRDLMKRSRGYQADQLDGDEGA
>NC_022584.1|WP_023026746.1|369169_369613_+|flavodoxin
MTLAKIVFASMTGNTEEIADIVADKFRDLGVEVEVDECTTVDAEDFLEADIAVVATYTYGDGELPDEIVDFYEDLAGLDLNGKIYGVVGSGDTFYDEFCKAVDDFDRVFAATGAVKGSECVKVDLSAEDEDIEKLEAFAEEVVAKVG
>NC_022584.1|WP_023026745.1|368053_368992_-|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA
MQITQDILEKINQYDTIILHRHMNPDPDAIGSQVGLKEIIQTNFPDKRVLATGFNEPTLAWMASMDTVTDEDYAGALVIVCDTANTPRIDDKRYTSGDFLVKIDHHPNDDAYGDLLWVDTDSSSTSELITLLALEQKLEITPEAARLLYAGIVGDTGRFLYPSTTSRTFEMVAHLRSFNFDFAGLSRQMDSMSSKIAKLQGYVYDHLEIDENGASRVTLTQELLKHYQITDAETAAIVSAPGRIEDVSVWAIFVEQADGHYRVRMRSKALVINEIAKRHDGGGHPLASGANSYSLEENEQIYRELQEVAKTK
>NC_022584.1|WP_023026744.1|366878_367871_-|hypothetical-protein
MHKHRIFIIVAAALTAISTFLPWSTLNGGSFGSYSFSGIRGEFGWVIVVLAIGAIVLACLPNIAPPMNKNFSIGVIAIGILESLITIITMFRVLGASSEFGDGFSIGFGLIIAVIASIALVVTGLLAMSGGKITKGTFQELASTSRGFAQSVASSVQSPQQPGQPGQQQWQQPQQGFGQPAPGQGFQQAPQQGFGQPAPGQGFQQAPQQGFGQPGQQQWQQPQQGFGQPAPGQGFQQAPQQGFGQPAPGQGFQQAPQQGFQQAPQQGFQQPQQGFQQAPQQGFQQPQQGFQQAPQQPQQGFQQAPQQPWQPQEQQQPQQPEQPTTEPGQE
>NC_022584.1|WP_023026753.1|380299_381112_+|PrsW-family-intramembrane-metalloprotease
MKRKSILFLFLFLLSIGLAYETQSITAGWMTGSQYGIIGISVLLLLVYAIPAVWALFHFAKKWKLSWIPVLFSLLGGGFIAGWLSSFANTYFHEMIQAVAPNSDFWNQYESAIAGPLFEEPFKLIPIFFVLYLFNVRRIKSIFLLAIASGLGFQIVEDFAYIRQDMPEGFSYAVSGILGRIMNGVVSHWVYTALFMVGLYLILQATKGRKELMLTGWFYFISGFGLHFVGNSPFGQIETELPLAIPFLTAVGLFLIYQAYLTVQSLDQGN
>NC_022584.1|WP_023026754.1|381155_382529_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MITREFDTIAAISTPLGEGAIGIVRLSGTDSFKIAQKIFKGKDLSNVASHTLNYGHIVDPDKDEILDEVMVGAMRSPKTFTREDIIEINTHGGIAVTNEILQLVIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSDLINNTRQEILNTLAQVEVNIDYPEYDDVEEATTEIIREKTTEFEALLTNLLKTARRGKILREGISTAIIGRPNVGKSSLLNNLLREEKAIVTDIEGTTRDVIEEYVNINGVPLKLVDTAGIRETEDIVERIGVERSRKALKEADLVLLVLNASEPLTDQDRQLLEISQDSNRIILLNKVDLPEKIEIDQLPEDYIKISVLKNQNIDQIEDRINALFFENAGLVEQDATYLSNARHISLIEKAVESLQAVNEGLAMGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLFSQFCLGK
>NC_022584.1|WP_023026755.1|382691_383390_+|ribose-5-phosphate-isomerase-RpiA
MVNLKEQVGIKAAEFVKDGMIVGLGTGSTAYYFVAELGRRIKEEGLKITAVTTSSVTYEQAEGLGIPLKAIDDVEVVDLTVDGADEVDLALNGIKGGGGALLMEKIVATNSKDCIWIVDESKQVETLGAFKLPVEVVQYGAENLFRHFEKKGYSPAYREKDGQRFVTDQGNYIIDLDLKVIQDAEALANELDHTVGVVEHGLFLNMISKVIVGTPEGPVIIEKWVSLERGRV
>NC_022584.1|WP_023026756.1|383455_384667_+|phosphopentomutase
MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISKAVGLNVPNMAKLGLGNIPREQALKTVPAESNPTGYATKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRRDLAVSPFAPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDNLIKAMKSEDFKHGFSFTNLVDFDALYGHRRDPHGYRDCLHEFDERLPEIIAAMKEDDLLMITADHGNDPTYAGTDHTREYIPFLAYSPSFKGSGLIPVGHFADISATVADNFGVEKAMIGESFLDKLV
>NC_022584.1|WP_023023068.1|384668_385211_+|DUF1697-domain-containing-protein
MMRFALLVRGINVGGKNKVVMAQLRQELTELGLEQVETYINSGNIFFTTGLSRSQLLECLSTFFETHYPFIERFSLLSRKDYEAECANLPQWWTEEMARKDVLFYTEGLDRESLEEKLLALKLGDEVLHFGKLAVFWGKFSEASYAKTAYHKHLMKMPFYREITIRNANTFDKIGRLLKK
>NC_022584.1|WP_023026757.1|385224_386034_+|purine-nucleoside-phosphorylase
MTFLDKINETAAFLKGKGVEAPEFGLILGSGLGELAEEIENAVVVDYSDIPNWGQSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKVLGCEGVLVTNAAGGIGFGPGTLMAITDHINMTGQNPLIGENLDDFGPRFPDMSKAYTPAYREIAHKVADKLGIKLDDGVYIGVTGPTYETPAEIRAYKTLGADAVGMSTVPEVIIAAHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL
>NC_022584.1|WP_042361398.1|387660_388371_+|purine-nucleoside-phosphorylase
MSIHIAAKQGEIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNGDVHVRELVLAQAAATNSNIIRNDWPMYDFPQIASFDLLDKAYHIANDLGMTTHVGNVLSSDVFYSNYFEKNLELGKWGVKAVEMEAAALYYLAAQHHVDALAIMTISDSLVNPEEDTTAEERQNTFTDMMKVGLETLIAD
>NC_022584.1|WP_023023078.1|388370_389129_+|hypothetical-protein
MTEYLHDEWLYDLQTYQYGRALRSAKKQKEVPELVLTLLDLMAERRELNIQPIMNLKLRTELLEATGFQLFWHEDPEEEQLANYLYDLEAKLRNDQMIDFIRAVSPAIYRIFMRLIEMQIPDIADYIHNSKESSYDHWKFDKIRSSDDPALQNFHSESAVNSSSLTELILLLDLPDSTKDAAKQLRELEKSVRNPLAHLIKPFDEEELHRTTGFSSQHFMELLVSLAQETGIVYQREPFYFDQANAVIEALL
>NC_022584.1|WP_023023080.1|389139_389871_+|NAD-dependent-protein-deacylase
MDKLKELQDVIDRSQNIVFFGGAGVSTESNIPDFRSSDGVYSVTLGRHFTAEQLVSHTMFERYPEDFFDFYKKYLIYPDAKPNAAHCYLARLEETGKLKAVVTQNIDSLHEMAGSKKVLKLHGSADRNYCTGCQRFYDLEAFLALAGTIPHCLDCGKVVKPDVTLYEEPLDMDVFSQAARAIQEADLLIIGGTSLVVYPAASLIQYFQGKNLVVINKTNIPQDKQADLVIEGKIGQVFSKLRQ
>NC_022584.1|WP_023023082.1|389943_390852_-|LysR-family-transcriptional-regulator
MRIQQLHYIIKIVETGSMNEASKQLFITQPSLSNAVRDLEKEMGIDIFIRNPKGITLTKDGMEFLSYARQVVEQTQLLEERYKNPVANRELFSVSSQHYAFVVEAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEIGVLFLNGYNRDVLSKMLDDSHLKATHLFTAQPHIFVSKTNPLANKDVVKLEDLEDFPYLSYDQGTHNSFYFSEEILSQEYHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYIQHEKASLSKMGEKFIEYLLEEVRFDK

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Crispr_ID: NC_022584_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022584_3

667679-667761

Orphan

Consensus_repeat	Method
TTCTGGTGTCTGCCACCGCTTGGCCCTTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022584_3

>merge|NC_022584|3|667679-667761|CRISPRCasFinder
TTCTGGTGTCTGCCACCGCTTGGCCCTTACGTCCAAGATTGCTATCGGATTTCGTTCTGGTGTCCGCCACCGCTTGGCCCTTA

>NC_022584|3|2|667679-667761|CRISPRCasFinder
TTCTGGTGTCTGCCACCGCTTGGCCCTTA	CGTCCAAGATTGCTATCGGATTTCG
TTCTGGTGTCCGCCACCGCTTGGCCCTTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_022584.1\|WP_023026943.1\|659866_660151_-\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_023026944.1\|660225_666459_-\|helicase-SNF2	unknown	unknown	gnl\|CDD\|226993
NC_022584.1\|WP_023026950.1\|676413_676902_-\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_001842085.1\|659345_659543_+\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_001054257.1\|673402_674257_-\|conjugal-transfer-protein-TrbL	unknown	unknown	unknown
NC_022584.1\|WP_003042486.1\|676891_677191_-\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_023026939.1\|656785_657169_-\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_023026942.1\|658544_659186_-\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_042361418.1\|667052_667619_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376232
NC_022584.1\|WP_023026940.1\|657165_657399_-\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_000627865.1\|674273_674516_-\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_001097589.1\|672989_673349_-\|PrgI-family-protein	unknown	unknown	gnl\|CDD\|378907
NC_022584.1\|WP_023026945.1\|666491_666902_-\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_023026947.1\|667856_670670_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|380090
NC_022584.1\|WP_023026948.1\|670681_672997_-\|ATPase-AAA	unknown	unknown	gnl\|CDD\|274279
NC_022584.1\|WP_042361419.1\|674536_676414_-\|TraM-recognition-domain-containing-protein	unknown	unknown	gnl\|CDD\|226036
NC_022584.1\|WP_023026941.1\|657449_658535_-\|DUF3991-domain-containing-protein	unknown	unknown	gnl\|CDD\|379043
NC_022584.1\|WP_023026951.1\|677524_678112_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NC_022584.1\|WP_000998893.1\|659556_659853_-\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_000840776.1\|678114_678348_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_022584.1\|WP_042361419.1\|674536_676414_-\|TraM-recognition-domain-containing-protein	gnl\|CDD\|226036	COG3505, VirD4, Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion].	3.05924e-58
NC_022584.1\|WP_023026944.1\|660225_666459_-\|helicase-SNF2	gnl\|CDD\|226993	COG4646, COG4646, DNA methylase [Transcription / DNA replication, recombination, and repair].	4.33289e-21
NC_022584.1\|WP_023026947.1\|667856_670670_-\|CHAP-domain-containing-protein	gnl\|CDD\|380090	pfam18013, Phage_lysozyme2, Phage tail lysozyme. This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.	2.01336e-36
NC_022584.1\|WP_023026948.1\|670681_672997_-\|ATPase-AAA	gnl\|CDD\|274279	TIGR02746, hypothetical_protein, type-IV secretion system protein TraC. The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.	1.59918e-14
NC_022584.1\|WP_001097589.1\|672989_673349_-\|PrgI-family-protein	gnl\|CDD\|378907	pfam12666, PrgI, PrgI family protein. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 116 and 146 amino acids in length. This protein is found in an operon that is part of a Type IV secretion system.	8.01688e-15
NC_022584.1\|WP_023026941.1\|657449_658535_-\|DUF3991-domain-containing-protein	gnl\|CDD\|379043	pfam13154, DUF3991, Protein of unknown function (DUF3991). This family of proteins is often associated with family Toprim, pfam01751.	5.88562e-05
NC_022584.1\|WP_042361418.1\|667052_667619_-\|hypothetical-protein	gnl\|CDD\|376232	pfam18813, PBECR4, phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4. A predicted endoRNase of the Barnase-EndoU-ColicinE5/D-RelE like nuclease fold found in polyvalent proteins of phages and conjugative elements. The predicted active site contains a conserved histidine residue.	1.33187e-20
NC_022584.1\|WP_023026951.1\|677524_678112_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.59203e-08

>NC_022584.1|WP_042361418.1|667052_667619_-|hypothetical-protein
MANSRDYCNPNYTEKIKLQHFFNRLQIAASFFKEHFVGKIMYYETEIESVELHFSPTNFMHLCGVDYRKGAGSFFDDCLNRHIIIDELKIKKDGTTMQKLQVLGSIEELLGKHVHLTGSGRYLYLEFDYALRTRKQILALTLKETSKKIVPQSLLDLKRKTVFPKGQKVISIYSKHLQTSELFYYLKD
>NC_022584.1|WP_023026945.1|666491_666902_-|hypothetical-protein
MEAIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEIEEGTNSLEKDLQDIDQTSITEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENQQDLEDLYTYYMRTDAVSLLSSDLEISPQEVEMEIEL
>NC_022584.1|WP_023026944.1|660225_666459_-|helicase-SNF2
MKGASMEVIQLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFLTKEGKIEEIPHVYSFHQDIISFLEASSENNDQDLESYTRNFGQAGLSKLSQLSNFEKNLVLEVATYNLFTRFYIQSEKEKLTPLSELVFHQNQDVNLVNVYRVANNLSDRISRDIEEFLLMVDSKELKKEVLEIHFEEKEGDVLAYLGSELMATLDIVTDLVHHEENYTQLPLTQKLKIITYFDEVKAIREKSKQVEEAVLPLDNIDQVEENVEVHSLTKVDKIVEEALREYPIGSQVNYKGQVFQLVSIENAQLNGLVRLELFNDSNKLFEENPILYLNSLEEIEQVLSHVELEKEDSEIEMDSSSESQEIDLFSYLEEDNEKDKETKTLIVGIEETDVPVLDFVFPDDLENFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLANEFFDELNPKYESERLTLRSLVSKSEYSTMKQSSLTAYYTDPMIILQIWQKLLDDGFEGGRILDPSMGTGNFFAAMPRSIREKSELYGVELDSVTGAIAKQLHPNTHIEVRGFEEVPYQNNSFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTMDKRTDNVLQEIKTNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKDQEKNLYDEELVFSGSISFEEDKRVWINPYFDGKYNTQVLGEYEVRNFNGGTLNVKGESETLATDITEALENVEAPKQIDNSLKAPVFIQEEIDNSIPSRIRENLALYSFGYEGNQIYYRDTHGIRKSSKVDEISYYVDEKGDFKSWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGLFKKTVFYESPLSDKDISRIKGMVDLRETYQSLIEIQRHQDYSRADFQELLSKLNREYDRFVSQFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPERVIARVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQASILDELGDQVLMDPESYLRGERKYLSKNQFLSGDILNKIEVVQLLVEENNQEFDWSHALDLLESVRPQRIHLADIEFKIGSRWIPQSVYGKFAFECFTNREFELSSSDVEQVIEVNPVDGQVHLRTSFAYRYPSAKDSSLGVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHLQELFQEFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAIQRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKFFPTKKVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDKLNELREIKTHSENKYTVKEAEQSISGLERQLEELQRFNRDSFIDFENLGIDFLFVDEAHHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSISELYTMMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLPELMKIYKETADIQTQDMLDLPVPEARIIPIESELTENQKLYLEELVMRSDAVKCGTVDPSQDNMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMENKATQMIFSDIGTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEVRILLASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYITKGSFDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKYKMELENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEMSKDQAFSMTVGKQVFEQRAEAGESLHRLIRHNQADSKEFRTLASYRGFDIKMLSLPTNQPLPETFSVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKDDQVKTQNLLDELKDKWTTAKVEIEKNFPKEEDYQTKKAEYDVLAPLIETDTDLDIIDQALRQFHEKGNEKEEQLSFELD
>NC_022584.1|WP_023026943.1|659866_660151_-|hypothetical-protein
MMEDTYYQLEEALVQGFQTPEEYQTYKELKEHYEEVTGDYSFSKRELTSQLEIALQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID
>NC_022584.1|WP_000998893.1|659556_659853_-|hypothetical-protein
MNDLLLIPVIFLAVGGILILLWRLFLIASGLFLIGFISFLIFVEVYGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRFINSKTKESM
>NC_022584.1|WP_001842085.1|659345_659543_+|hypothetical-protein
MKNLKEENLRRALSHIERHKQAINTSNNSEDNDFHKLLLQFSYEVYERIKANKKPYPNLDSDKVF
>NC_022584.1|WP_023026942.1|658544_659186_-|hypothetical-protein
MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIELAAAKLVENKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSSQNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYKVTYVSDLKNANQSKTNQTETRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSIPSLPNTTTK
>NC_022584.1|WP_023026941.1|657449_658535_-|DUF3991-domain-containing-protein
MEIEECKQISILDVASRLGISFKQVSTSVYEHSEHDSFRIFSTTNTFKWFSRDIQGDVIDFVRLVQGISFKEALAFLSEEPFQKEAVQEKRERLFYYPLKRVEDSNCSLARYYLTECRGISEEIIQKMIQQGLIAQASWKTNETVEPVIVFKSYDHRHKLQAASLQGIYKNHSLPRERLKTILKGSHGHVGISFDIGKPNRLVFCESFIDLMSYYELHQQTLTDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVTPSKLLHLINTIRDTTTYFDNHPDLLTLAVDCDDAGKDFSDKLSQSGFPVLLDLPNNESGKEKIDWNDILREKKSDFQFKLETVKETFGNPPVRQLSQCLEL
>NC_022584.1|WP_023026940.1|657165_657399_-|hypothetical-protein
MTIIERLEEKVTRQESKVARETEKLAAYREQLETAMFATFKRRQIISHMSFEEALDHAFGKERQFDDSEFRKDEMSE
>NC_022584.1|WP_023026939.1|656785_657169_-|hypothetical-protein
MTKDWNFNQPLESKSENQGDSDKIAALFGNHQGGNEVNYEAAFQKRKQAPVTESNSSSKPQVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEELHTLIDTKNKDNKKLQSIYDAISELH
>NC_022584.1|WP_023026947.1|667856_670670_-|CHAP-domain-containing-protein
MKDKREIIRARKAFRRSLKDEKKFLKQGKKEVRKQKKDSAGLDEKAWKKEIKEKLEEMREASKERVRQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRLKIAEKQFREAKVEAKEERKESRKERKTNQKFLYGQESKHKSNFFFQGKSLEELKAKKEVKATKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKGKRYSRISYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNRFRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPVTWIVGGIVFLLLLIMSFFLGFSSASLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPVHLFSSETYKDYLSTLWHDLNDGDDLKSMQDLYETPKYKLSKDDQEEIKELKEEGVYTSMQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDGVVSLDGNDVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKYKNKKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAAILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDETWLAIGGPAIYSGAYPNILHRGLGLGQWTDTADGSTRHTALLNYAHIKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFGNTGSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGHAKSDLQSLEGVRGDLYENSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDWVATASSLGGETGSTPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGGNPNYTFRKISQADSAISFAYTTK
>NC_022584.1|WP_023026948.1|670681_672997_-|ATPase-AAA
MTNKKEEVKGKKEEVLPSTANTLSYQALYQNGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINALDDQTNFQLTIFNKRLNLEKFRQSVLYEEKEDGYNSYRKELNRMMNQNLDSGENNFSAVKLISFARKDSNPKQAYRSLSQIGEYFKSGFSEIDARFESLAGEERVNLLADMLRGEHHLPFSYRDLTRSGQTTRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHAQSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTMTETGDKLFQTVFLIGVFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLPFGCDFLEGVSRSLLTSNIAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPSGLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRTFGGEMIDIAPDSQTYLNVLDLSEENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQSFKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKKLGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRVRKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEKYLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN
>NC_022584.1|WP_001097589.1|672989_673349_-|PrgI-family-protein
MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLFFWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGPEHEKKIKYIKETKNFND
>NC_022584.1|WP_001054257.1|673402_674257_-|conjugal-transfer-protein-TrbL
MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYNPTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYIMVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFFALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMVYAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQRTARSILGM
>NC_022584.1|WP_000627865.1|674273_674516_-|hypothetical-protein
MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNLATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI
>NC_022584.1|WP_042361419.1|674536_676414_-|TraM-recognition-domain-containing-protein
MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLMEGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTLKEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNLIQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLNRMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSKTEYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYGTENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGQEKSMVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIPDFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFKFMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANMPVFKSKKYNSTKHPNWKYLANQETDERWWNYQINPLNQRQENHLEGLRIRDLTFESSLK
>NC_022584.1|WP_023026950.1|676413_676902_-|hypothetical-protein
MSSEQQERIAVQYAERSLLFTVRSLLKILEWSRRQALAQDSAYKIGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFYTKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEMVR
>NC_022584.1|WP_003042486.1|676891_677191_-|hypothetical-protein
MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKRVGIFDGKAVEVTLREPYSRDLLQVVKSIKQHQKLIAYRYKEGKLLFVKKEASDVL
>NC_022584.1|WP_023026951.1|677524_678112_-|CPBP-family-intramembrane-metalloprotease
MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGSSLISFLWMYGQRKQVAKVNMKIRIKWIGIGLASLLIISLCFSLIRAQGSTNQANLIGLQYQVPWFSFLLFLINASMVEEFLYREILWDLVRKLDIRIALTSVLFALAHHPGTILAWCLYVSLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF
>NC_022584.1|WP_000840776.1|678114_678348_-|hypothetical-protein
MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQKIRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR

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Crispr_ID: NC_022584_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022584_4

1624728-1624819

Orphan

Consensus_repeat	Method
GTTGAAGTTGTAGTCGGTTCTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022584_4

>merge|NC_022584|4|1624728-1624819|CRISPRCasFinder
GTTGAAGTTGTAGTCGGTTCTTCGCTTGTCGTTGTTGTAGTGGTTGTAGCTTCTTTGGTTGTGGTCGTAGTTGAAGTTGTAGTCGGTTCTTC

>NC_022584|4|3|1624728-1624819|CRISPRCasFinder
GTTGAAGTTGTAGTCGGTTCTTC	GCTTGTCGTTGTTGTAGTGGTTGTAGCTTCTTTGGTTGTGGTCGTA
GTTGAAGTTGTAGTCGGTTCTTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022584.1\|WP_001265622.1\|1621163_1621313_+\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|179075
NC_022584.1\|WP_023024966.1\|1627778_1629053_+\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234586
NC_022584.1\|WP_023027509.1\|1617697_1619401_-\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|234861
NC_022584.1\|WP_023027508.1\|1617307_1617649_+\|metal-sulfur-cluster-assembly-factor	unknown	unknown	gnl\|CDD\|225062
NC_022584.1\|WP_023027518.1\|1636551_1637835_+\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240542
NC_022584.1\|WP_023027513.1\|1623988_1624219_+\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_023027515.1\|1633710_1634211_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|226489
NC_022584.1\|WP_042361311.1\|1637840_1638464_+\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|319825
NC_022584.1\|WP_023027514.1\|1631303_1633514_+\|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|236436
NC_022584.1\|WP_023027511.1\|1620614_1620815_+\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|227214
NC_022584.1\|WP_000171299.1\|1621606_1621795_+\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_003009516.1\|1620965_1621148_+\|50S-ribosomal-protein-L32	unknown	unknown	gnl\|CDD\|234901
NC_022584.1\|WP_023024968.1\|1629396_1631178_+\|heme-transporter-CcmD	unknown	unknown	gnl\|CDD\|227904
NC_022584.1\|WP_023024964.1\|1626595_1627588_+\|aspartate--ammonia-ligase	unknown	unknown	gnl\|CDD\|225304
NC_022584.1\|WP_006595204.1\|1633526_1633667_+\|hypothetical-protein	unknown	unknown	unknown
NC_022584.1\|WP_042361310.1\|1619589_1620612_+\|SPFH-domain-containing-protein	unknown	unknown	gnl\|CDD\|259800
NC_022584.1\|WP_013904661.1\|1621787_1622399_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225095
NC_022584.1\|WP_023027517.1\|1635006_1636491_+\|threonine-synthase	unknown	unknown	gnl\|CDD\|236418
NC_022584.1\|WP_023027512.1\|1622604_1623453_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_022584.1\|WP_023027516.1\|1634215_1634812_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl\|CDD\|379137

Protein	Function_ID	Function_description	E-value
NC_022584.1\|WP_001265622.1\|1621163_1621313_+\|50S-ribosomal-protein-L33	gnl\|CDD\|179075	PRK00595, rpmG, 50S ribosomal protein L33; Validated.	6.45602e-18
NC_022584.1\|WP_023024966.1\|1627778_1629053_+\|histidine--tRNA-ligase	gnl\|CDD\|234586	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed.	0
NC_022584.1\|WP_023027509.1\|1617697_1619401_-\|dihydroxy-acid-dehydratase	gnl\|CDD\|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
NC_022584.1\|WP_023027508.1\|1617307_1617649_+\|metal-sulfur-cluster-assembly-factor	gnl\|CDD\|225062	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only].	1.10878e-31
NC_022584.1\|WP_023027517.1\|1635006_1636491_+\|threonine-synthase	gnl\|CDD\|236418	PRK09225, PRK09225, threonine synthase; Validated.	0
NC_022584.1\|WP_023027515.1\|1633710_1634211_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|226489	COG3981, COG3981, Predicted acetyltransferase [General function prediction only].	1.99983e-72
NC_022584.1\|WP_023027514.1\|1631303_1633514_+\|anaerobic-ribonucleoside-triphosphate-reductase	gnl\|CDD\|236436	PRK09263, PRK09263, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
NC_022584.1\|WP_023027511.1\|1620614_1620815_+\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|227214	COG4877, COG4877, Uncharacterized protein conserved in bacteria [Function unknown].	2.22252e-27
NC_022584.1\|WP_003009516.1\|1620965_1621148_+\|50S-ribosomal-protein-L32	gnl\|CDD\|234901	PRK01110, rpmF, 50S ribosomal protein L32; Validated.	1.12173e-17
NC_022584.1\|WP_042361311.1\|1637840_1638464_+\|HAD-IA-family-hydrolase	gnl\|CDD\|319825	cd07523, HAD_YsbA-like, uncharacterized family of the haloacid dehalogenase-like superfamily, similar to the uncharacterized Lactococcus lactis YsbA. The specific function of Lactococcus lactis YsbA is unknown. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.42825e-65
NC_022584.1\|WP_023024964.1\|1626595_1627588_+\|aspartate--ammonia-ligase	gnl\|CDD\|225304	COG2502, AsnA, Asparagine synthetase A [Amino acid transport and metabolism].	0
NC_022584.1\|WP_023027518.1\|1636551_1637835_+\|MATE-family-efflux-transporter	gnl\|CDD\|240542	cd13137, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	1.54438e-83
NC_022584.1\|WP_042361310.1\|1619589_1620612_+\|SPFH-domain-containing-protein	gnl\|CDD\|259800	cd03402, SPFH_like_u2, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes an uncharacterized family of proteins similar to stomatin, prohibitin, flotillin, HflK/C (SPFH) and podocin. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Many superfamily members are associated with lipid rafts. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Microdomains formed from flotillin proteins may in addition be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and are known to interact with a variety of proteins. Stomatin interacts with and regulates members of the degenerin/epithelia Na+ channel family in mechanosensory cells of Caenorhabditis elegans and vertebrate neurons and participates in trafficking of Glut1 glucose transporters. Prohibitin may act as a chaperone for the stabilization of mitochondrial proteins. Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection. Flotillins have been implicated in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease, and in cancer invasion and metastasis. Mutations in the podocin gene give rise to autosomal recessive steroid resistant nephritic syndrome.	5.06129e-125
NC_022584.1\|WP_013904661.1\|1621787_1622399_+\|hypothetical-protein	gnl\|CDD\|225095	COG2184, Fic, Protein involved in cell division [Cell division and chromosome partitioning].	1.314e-23
NC_022584.1\|WP_023027512.1\|1622604_1623453_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	7.55697e-07
NC_022584.1\|WP_023024968.1\|1629396_1631178_+\|heme-transporter-CcmD	gnl\|CDD\|227904	COG5617, COG5617, Predicted integral membrane protein [Function unknown].	5.32083e-06
NC_022584.1\|WP_023027516.1\|1634215_1634812_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl\|CDD\|379137	pfam13353, Fer4_12, 4Fe-4S single cluster domain. This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.	2.49335e-78

>NC_022584.1|WP_023027513.1|1623988_1624219_+|hypothetical-protein
MVTKYYKYIPWLILGAIGSYESATYFGHSTFDTLYLSIVFMIVYVALFILHEKYLKYKYKEIFTHIMSNPEKDHHP
>NC_022584.1|WP_023027512.1|1622604_1623453_-|helix-turn-helix-transcriptional-regulator
MRWDYGTIYKKIRKSKHISQEEVCQDYTSRAHLSRIESNQVVPSFELMEHLLKQVGLDFEEFRYICHSYHHSDREEIILLAEDNNAYQSNDKLFELKNKSVAYLKKHLNDIPVLNILKRVEVILCLRESGPDEKVRTMATEAWNEIKNQDVWYHSDLKLIVVILFTLPLETVISICDEVIDRLNDYSDYTEILPTKYKLLSNLASIFLWNGLMEKCTSISYLLLDTAKKSKRYDFLGNAKVTLGICLTDKKLVDEGLQLLELTDEQTLLEACQSDVNRFFKK
>NC_022584.1|WP_013904661.1|1621787_1622399_+|hypothetical-protein
MVKNQYEGYEYIDPNHQYTYPNSTVLINKQNVTNIEEAYRNEHLFVTKRLADLRLKAIKVYSMSNILAIHNYLFQDVYAWSGQYRKVNISKSGNPFMSIQSFNAAETYINHLIHSYHQTANSRDEIIKHLAKILDNLNYFHPFREGNGRTQREVIRSLALSKGYSAQIRVEQDDEIYNLYMDGTVYGELWKLEKLFDKILKEI
>NC_022584.1|WP_000171299.1|1621606_1621795_+|hypothetical-protein
MTLDVNKEELTILGIPFDNFSDFDTVWYAIGSSMIENYEPTVQDVIDLKTYVINKRKELNIG
>NC_022584.1|WP_001265622.1|1621163_1621313_+|50S-ribosomal-protein-L33
MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVVFTEVK
>NC_022584.1|WP_003009516.1|1620965_1621148_+|50S-ribosomal-protein-L32
MAVPARRTSKAKKNKRRTHYKVTAPSVNFDEATGDYSRSHRVSLKGYYKGRKIAKAASAE
>NC_022584.1|WP_023027511.1|1620614_1620815_+|PTS-ascorbate-transporter-subunit-IIC
MADQKKKQIPLRLSAKLYAALASWAEDDFRSVNGQIEYLLTECVKQRKKDGKYVSETIDEPFEIDL
>NC_022584.1|WP_042361310.1|1619589_1620612_+|SPFH-domain-containing-protein
MEEKILTQKKNGLAVLVGLLVGDLILVFAFISAIASLPEGFPLAIGVITCIFLFIASLVCYAGIKIIKPQEALVLTLFGDYIGTIREAGIYFVNPFCVAVNPANNTRLGQSGDVTTKSPMSVSKTAEGKNISIETGKKNISLKVMTLNNSRQKINDCLGNPVEIGIAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVAPNVDTTGDGQADEGSLRGSSEIVASRIREEIQERVKDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDARKMIVDGAVGMVEMALERLSEGEIVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSLY
>NC_022584.1|WP_023027509.1|1617697_1619401_-|dihydroxy-acid-dehydratase
MTELDTRHRSSVYDSMVKSPNRAMLRATGMTDENFEKPIVGVISTWAENTPCNMHLHDFGKLAKEGVKDAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDIIADSIEAAMGGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLNGKDIDLVSVFEGIGKWNHGDMTAEEVKQLECNACPGPGGCGGMYTANTMATAIEVLGMSLPGSSSHPAESADKKADIEEAGRAVVKMLEMGLKPSDILTREAFEDAITVTMALGGSTNATLHLLAIAHAANVDLTLEDFNDFQERVPHLADLKPSGQYVFQDLYNVGGVPAVMKYLLKNGFLHGDRITCTGKTVAENLEAFADLTPGQKVIMPLENPKRADGPLIILKGNLAPEGAVAKVSGVKVRNITGPAKVFDSEEAAIEAVLSDEIVDGDVVVVRFVGPKGGPGMPEMLSLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQVGGPIAYLHTGDMVTVDQDTKEITMHVSDEELAKRKAETTLPPLYSRGVLGKYAHTVSSASRGAVTDFWNMEQSGKQ
>NC_022584.1|WP_023027508.1|1617307_1617649_+|metal-sulfur-cluster-assembly-factor
MREDIKINDRALALEKQLIEKLELVFDTDVELDVYNLGLIYELDLDEEGICKVVMTFTDTACSCAESLPIEIVARLKEIDGIEDVKVEVTWSPAWKITRISRYGRIALGLPPR
>NC_022584.1|WP_023024964.1|1626595_1627588_+|aspartate--ammonia-ligase
MKKSFIHQQEEISFVKTTFTQYLKDKLEVVEVQGPILSKVGDGMQDNLSGVENPVSVKVLQIPNETYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPDEDSLDATHSVYVDQWDWEKVIPNGNRNLAYLKETVEKIYKAIRLTELAVEARYDIESILPKQITFIHTEELVERYPELTPKERENAITKEYGAVFLIGIGGVLSDGKPHDGRAPDYDDWTTETENGYKGLNGDILVWNDNLGAAFELSSMGIRVDEDTLKRQVAITGDQDRLELEWHRALLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVREQYENIL
>NC_022584.1|WP_023024966.1|1627778_1629053_+|histidine--tRNA-ligase
MKLQKPKGTQDILPQESAKWQYVEGFARETFKKYNYAEIRTPIFEHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQKPSKVYYIGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMADQFFKEIGIENVVLHLNTLGSTASRTAYRQALIDYLLPMKDQLSKDSQRRLEENPLRVLDSKEKEDKQAVENAPSILDYLDEESQAHFDAVRAMLDGLGIAYVIDTNMVRGLDYYNHTIFEFVTEVDGNELTVCAGGRYDGLVEYFGGPATPGFGFGMGLERLLLILDKQGVELPVEASLDVYVAVLGSEAEVASLELVQALRRQGFIAERDYLGRKLKAQFKSADVFGAKTIIALGGSEVESGQITVKNNQTRQEVTTSIEEVKNDFQTILNQL
>NC_022584.1|WP_023024968.1|1629396_1631178_+|heme-transporter-CcmD
MSEKEKESHKLGLSVGSNFQDTQELRKVLEQSISREEEVLTASQPVESDQNQEESQVNGEGVETEASTETLSRLSRSGHSRKEKLEARSRDQEDVEESLENQEDEKPLGRYAIKRPVPLSLPIALSVLLGMVHVALPFINLVATNQQTQDLYAGWAISQGQVPYGHFFGVNGLLYYGLSGLGSLVGGQVLLVAFQILAYFFAGTSLYRMVRSLVASEKIAGQVQLLFYLLAGVLGFGGNYAVFYALPFLFGSMNFILAYLEGEKTDESFVAYGAGACLAFMIVPWLSVIFYLLAFLGLTAYHVKQKKLAHGFYQFLAALLGFSLVFYPLGYITVWNGSFGYAIHQTLYSLRSLQFDAGHLFANLVYYCLLLLTLGFASAFVMSFRKVSTSGQRVIRFMSWFGLLLVVAVVVGTPEQGAYQFLSLLPFGLPLLALWFAGDESTYQRRKMKNNSIWDLYFSSQAFLPILAMAYLVGYPVVNQLVLQSNLASDRSAIAQYIKSHSDSKDTIYAWDQTAHLYQESGRLAASALLTPTAYMGPKENRTNLINQIKQAKPKFIVVNKDLDVTSALQKVLTKNYEKVNQKGSQYTLYRYK
>NC_022584.1|WP_023027514.1|1631303_1633514_+|anaerobic-ribonucleoside-triphosphate-reductase
MITLREEHIQSLPQLFVEKRDGRKVKFDVDKIYRALVKATEEVTGLTPALEAKLETVTDRIVAEVLERFPRGVKIYEIQNVVEHELLQANEYAIAESYITYRTQRDFERSKATDINFTIGKLLNKDQAVVNENANKDSDVFNTQRDLTAGIVGKSIGLKMLPKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFEGMLRNGFKIGNAEVESPKSIQTATAQISQIIANVASSQYGGCSADRIDEVLAPYAEKNYKKHLKDAEEWVLPEKREDYAWQKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTNRFEREIQKAILEIRIKGLGSEHRTAIFPKLIFTLKRGLNLEPGSPNYDIKQLALECATKRMYPDVLSYDKIVELTGSFKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESGGDKEKFWEIFNERMNIAEDALVYRVERTKEATPANAPILYQYGAFGKRLGKYDQVDQLFRNRRATISLGYIGLYEVATVFYGPNWEENPEAKQFTIEIIKDMKKRVEEWSDQYDYHFSIYSTPSESLTDRFCRLDTEKFGKVPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGATGGFIHYCEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFAPTERGFTCPNCGNSDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKSAGHQVKD
>NC_022584.1|WP_006595204.1|1633526_1633667_+|hypothetical-protein
MGKYQLDDKGKAQVQRFHEKHSTGGINKKDRVASLREQFLKKAKKK
>NC_022584.1|WP_023027515.1|1633710_1634211_+|GNAT-family-N-acetyltransferase
MELRRPTLADKETVLDMMAEFEATQSAHDGGFWNAEAFVYEDWLETNMQKEMGINLPENRVPSIQFVLFDKSGHALGFLNLRLRLNEGLLNYAGHIGYSIRPSEQGKGYAKEALRQGLQVAKEKNIHRALVTCSMDNPASRAVILANGGQLEDVRNGTERYWIEVE
>NC_022584.1|WP_023027516.1|1634215_1634812_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MTWNTPKPGEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMFHCEGCYNVATWSFNAGIPYTKELEEQIMEDLAQPYVQGLTLLGGEPFLNTGILLPLVKRVKRELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDKSKRNLMLQFRGSSNQRIIDVQQSLKEGKVVIWDKLNDGKESYEQVKRE
>NC_022584.1|WP_023027517.1|1635006_1636491_+|threonine-synthase
MTLVYQSTRDAKNTVTASQAILQGLATDGGLFTPVSYPKVDLDFGILKDASYQEVAKLVLSAFLDDFTAEELDYCITNAYDSKFDTPAIAPLVKLDGQYNLELFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGTEIIVFYPKDGVSKVQELQMTTQTGDNTHVIAIDGNFDDAQTNVKQMFNDVELREKLAANKMQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIKAGDKVNFTVPTGNFGNILAAFYAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIFHLLGNDAVKTAELMNALNSQGQYELIDFDAEILDLFAAEYATEAETAAEIKRVYESDSYIEDPHTAVASAVYKKYQAATGDATKTVIASTASPYKFPVVAVEAVTGKSGLSDFEALAQLHEISGVALPPAVDGLETAPVRHKTTVAAAEMQSAVETYLGL
>NC_022584.1|WP_023027518.1|1636551_1637835_+|MATE-family-efflux-transporter
MSRQQQVDRQILRIALPAIGENFLQMLMGMVDSYLVAQLGLVAVSGVSVAGNIITIYQAIFIALGAAVVSLLSKSMGQKDQKAIARQATESIKVTVLLSLVLGTLSLCFGKELIAFLGVEAAVAEAGGIYLSLVGGSILLLGLMTTFGALVRVVHNPRTPMYVSLLTNVLNALLSSILIFVFGLGIAGAALGTVLSRLLGTYLLWRQVQLPFAPFCWGLDRDLLSLALPAAGERLMMRAGDIVIIAMVAVFGTRAVAGNAIGEVLTQFNYMPAFGIATATVMLVAKSLGQNDWQGIKQITNRSFWLSFLSMFPLALTIFLFGSPLTALYTMDPGALAASLSVILFSLLGTPLTAGTVIYTAVWQGLGNARLPFYATTIGMWVIRIGSGYLMGVVLGWGLPGIWAGTLLDNGFRWFFLKTLYHRKWKE
>NC_022584.1|WP_042361311.1|1637840_1638464_+|HAD-IA-family-hydrolase
MTRAFIWDLDGTLLDSYEAILDGIAETYAHYSIDFDREAVYAFILNQSVQALLEEVARENDLDAEEMNRYRASSLREKNAQVHLMPGARDILAWAKEEGIVQFVYTHKGKNAYPILEDLGILSYFQEVVTTDNGFRRKPDPEGVNYLVDKYQLDRSETYYIGDRTLDVDLADNAGIGSINFLDYKPDVNHTIHRLDEIRLYFKQEKS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_022584_2	2.10\|378714\|30\|NC_022584\|CRISPRCasFinder,CRT	378714-378743	30	MF417967	Uncultured Caudovirales phage clone 3S_16, partial genome	5207-5236	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KY065505	Streptococcus phage IPP69, complete genome	1319-1348	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KY065456	Streptococcus phage IPP15, complete genome	1319-1348	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KY065486	Streptococcus phage IPP46, complete genome	1319-1348	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KY065500	Streptococcus phage IPP64, complete genome	1319-1348	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	FR671407	Streptococcus phage 34117	36289-36318	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KT337344	Streptococcus phage phiARI0274b, partial genome	33601-33630	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	NC_024361	Streptococcus phage DCC1738, complete sequence	37045-37074	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KT337359	Streptococcus phage phiARI0468b-3, partial genome	30573-30602	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KT337354	Streptococcus phage phiARI0462, complete genome	39135-39164	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	NC_031929	Streptococcus phage phiARI0468-1, complete genome	39623-39652	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	FR671410	Streptococcus phage 8140	34543-34572	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	NC_024370	Streptococcus phage IC1, complete sequence	38618-38647	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	FR671405	Streptococcus phage V22	35812-35841	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	NC_024357	Streptococcus phage K13, complete sequence	38013-38042	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KT337351	Streptococcus phage phiARI0455b, partial genome	31282-31311	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	FR671411	Streptococcus phage 2167	34870-34899	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KT337362	Streptococcus phage phiARI0598b, partial genome	34425-34454	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KT337340	Streptococcus phage phiARI0031, complete genome	40524-40553	2	0.933
NC_022584_2	2.21\|379440\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379440-379469	30	MF417961	Uncultured Caudovirales phage clone 10S_15, partial genome	5927-5956	2	0.933
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	MK448904	Streptococcus phage Javan316, complete genome	1319-1348	3	0.9
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KT337367	Streptococcus phage phiARI0826b, partial genome	32635-32664	3	0.9
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	NC_031920	Streptococcus phage phiARI0004, complete genome	39665-39694	3	0.9
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	KT337369	Streptococcus phage phiARI0831b, partial genome	29689-29718	3	0.9
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	530077-530106	4	0.867
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	523485-523514	4	0.867
NC_022584_2	2.13\|378911\|30\|NC_022584\|CRISPRCasFinder,CRT	378911-378940	30	MK448960	Streptococcus phage Javan492, complete genome	14972-15001	5	0.833
NC_022584_2	2.13\|378911\|30\|NC_022584\|CRISPRCasFinder,CRT	378911-378940	30	MK448762	Streptococcus phage Javan447, complete genome	15099-15128	5	0.833
NC_022584_2	2.13\|378911\|30\|NC_022584\|CRISPRCasFinder,CRT	378911-378940	30	MK448965	Streptococcus phage Javan506, complete genome	16209-16238	5	0.833
NC_022584_2	2.13\|378911\|30\|NC_022584\|CRISPRCasFinder,CRT	378911-378940	30	MK448959	Streptococcus phage Javan488, complete genome	16209-16238	5	0.833
NC_022584_2	2.13\|378911\|30\|NC_022584\|CRISPRCasFinder,CRT	378911-378940	30	MK448849	Streptococcus phage Javan128, complete genome	12694-12723	5	0.833
NC_022584_2	2.13\|378911\|30\|NC_022584\|CRISPRCasFinder,CRT	378911-378940	30	MK448949	Streptococcus phage Javan460, complete genome	16869-16898	5	0.833
NC_022584_2	2.13\|378911\|30\|NC_022584\|CRISPRCasFinder,CRT	378911-378940	30	MK448958	Streptococcus phage Javan486, complete genome	15176-15205	5	0.833
NC_022584_2	2.13\|378911\|30\|NC_022584\|CRISPRCasFinder,CRT	378911-378940	30	MK448954	Streptococcus phage Javan476, complete genome	14575-14604	5	0.833
NC_022584_2	2.17\|379176\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379176-379205	30	MG969415	UNVERIFIED: Salmonella phage GE_vB_TR, complete genome	6609-6638	5	0.833
NC_022584_2	2.17\|379176\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379176-379205	30	MK448939	Streptococcus phage Javan440, complete genome	24730-24759	5	0.833
NC_022584_2	2.17\|379176\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379176-379205	30	MK448758	Streptococcus phage Javan433, complete genome	24730-24759	5	0.833
NC_022584_2	2.17\|379176\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379176-379205	30	MK448759	Streptococcus phage Javan439, complete genome	24730-24759	5	0.833
NC_022584_2	2.17\|379176\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379176-379205	30	KY065498	Streptococcus phage IPP62, complete genome	20418-20447	5	0.833
NC_022584_2	2.17\|379176\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379176-379205	30	MK448757	Streptococcus phage Javan427, complete genome	25514-25543	5	0.833
NC_022584_2	2.21\|379440\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379440-379469	30	NC_008723	Staphylococcus phage PH15, complete genome	2217-2246	5	0.833
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	AGRM01000007	Salmonella enterica subsp. houtenae str. ATCC BAA-1581 plasmid pSEHO0A2, complete sequence, whole genome shotgun sequence	31057-31086	6	0.8
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	NZ_CP030218	Salmonella enterica strain SA20075157 plasmid pSA20075157.1, complete sequence	42433-42462	6	0.8
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	NZ_CP030289	Salmonella enterica subsp. enterica serovar Gaminara str. SA20063285 plasmid pIncI1.1, complete sequence	84058-84087	6	0.8
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	NZ_CP024167	Salmonella enterica subsp. enterica serovar Gaminara strain CFSAN070644 plasmid pCFSAN024441_02, complete sequence	39894-39923	6	0.8
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	CP053410	Salmonella enterica strain 2014K-0203 plasmid unnamed, complete sequence	48630-48659	6	0.8
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	CP053415	Salmonella enterica strain 2011K-0868 plasmid unnamed, complete sequence	68237-68266	6	0.8
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	CP053327	Salmonella enterica subsp. salamae serovar 58:c:z6 strain 2013K-0366 plasmid unnamed, complete sequence	76559-76588	6	0.8
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MG592448	Vibrio phage 1.071.A._10N.286.46.A12, partial genome	40657-40686	6	0.8
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MG592400	Vibrio phage 1.016.O._10N.286.46.A11, partial genome	40621-40650	6	0.8
NC_022584_2	2.19\|379307\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379307-379336	30	NZ_CP019315	Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-3, complete sequence	74573-74602	6	0.8
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	NZ_CP034685	Bacillus sp. BD59S plasmid pBTBD59S2, complete sequence	163708-163737	7	0.767
NC_022584_2	2.6\|378450\|30\|NC_022584\|CRISPRCasFinder,CRT	378450-378479	30	NC_047815	Erwinia phage vB_EamM_Yoloswag, complete genome	228804-228833	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	NZ_CP013579	Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence	1020468-1020497	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	NZ_CP013546	Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence	914849-914878	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	NZ_CP013573	Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence	1020468-1020497	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MH001458	Mycobacterium phage Smeagol, complete genome	16959-16988	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MN369760	Mycobacterium phage KyMonks1A, complete genome	15939-15968	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MH371110	Mycobacterium phage Magnar, complete genome	15334-15363	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MH230878	Mycobacterium phage Oogway, complete genome	15594-15623	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MN585985	Mycobacterium phage Watermelon, complete genome	16482-16511	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MK061415	Mycobacterium phage Rhynn, complete genome	15669-15698	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	NC_022070	Mycobacteriophage Wheeler, complete genome	15938-15967	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MT657342	Mycobacterium phage Mule, complete genome	15663-15692	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MH338239	Mycobacterium phage Mryolo, complete genome	15375-15404	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	EU744251	Mycobacterium phage Jasper, complete genome	15465-15494	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	NC_023723	Mycobacterium phage Aeneas, complete genome	15956-15985	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	KC701493	Mycobacterium phage CASbig, complete genome	36818-36847	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	JN398369	Mycobacterium phage RidgeCB, complete genome	15444-15473	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	NC_022329	Mycobacterium phage PhrostyMug, complete genome	15660-15689	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	EU744249	Mycobacterium phage Lockley, complete genome	15553-15582	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	NC_041853	Mycobacterium phage Marcell, complete genome	15847-15876	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MH697575	Mycobacterium phage Adahisdi, complete genome	15849-15878	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	EU744252	Mycobacterium phage DD5, complete genome	16320-16349	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	MK359316	Mycobacterium phage Cueylyss, complete genome	15772-15801	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	NC_031041	Mycobacterium phage Papez, complete genome	17310-17339	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	KF024724	Mycobacterium phage Trouble, complete genome	15932-15961	7	0.767
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	JN699016	Mycobacterium phage Kugel, complete genome	15773-15802	7	0.767
NC_022584_2	2.12\|378846\|29\|NC_022584\|CRISPRCasFinder,CRT	378846-378874	29	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	424781-424809	7	0.759
NC_022584_2	2.14\|378977\|31\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	378977-379007	31	NZ_CP015943	Legionella pneumophila strain C9_S plasmid unamed2, complete sequence	31227-31257	7	0.774
NC_022584_2	2.14\|378977\|31\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	378977-379007	31	NZ_CP021276	Legionella pneumophila strain D-4040 plasmid unnamed2, complete sequence	17583-17613	7	0.774
NC_022584_2	2.14\|378977\|31\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	378977-379007	31	NZ_CP015952	Legionella pneumophila strain E5_N plasmid unnamed1, complete sequence	245-275	7	0.774
NC_022584_2	2.14\|378977\|31\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	378977-379007	31	NZ_CP016846	Carnobacterium maltaromaticum strain TMW 2.1581 plasmid pL21581-2, complete sequence	24748-24778	7	0.774
NC_022584_2	2.14\|378977\|31\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	378977-379007	31	MF001361	Enterococcus phage EF5, partial genome	69935-69965	7	0.774
NC_022584_2	2.14\|378977\|31\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	378977-379007	31	NZ_CP021278	Legionella pneumophila subsp. fraseri strain D-4058 plasmid unnamed, complete sequence	65480-65510	7	0.774
NC_022584_2	2.14\|378977\|31\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	378977-379007	31	NZ_CP015948	Legionella pneumophila strain E2_N plasmid unnamed1, complete sequence	35972-36002	7	0.774
NC_022584_2	2.14\|378977\|31\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	378977-379007	31	MF001358	Enterococcus phage EF1, partial genome	47381-47411	7	0.774
NC_022584_2	2.16\|379110\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379110-379139	30	MK448902	Streptococcus phage Javan308, complete genome	1301-1330	7	0.767
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	NZ_CP035095	Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid unnamed1, complete sequence	269996-270025	8	0.733
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	NZ_CP040345	Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence	229515-229544	8	0.733
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	NZ_CP009921	Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid pBMV_2, complete sequence	206951-206980	8	0.733
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	NC_016046	Oscillibacter valericigenes Sjm18-20 plasmid pOBV01, complete sequence	10769-10798	8	0.733
NC_022584_2	2.8\|378582\|30\|NC_022584\|CRISPRCasFinder,CRT	378582-378611	30	NC_041884	Acinetobacter phage vB_AbaM_ME3, complete genome	226624-226653	8	0.733
NC_022584_2	2.9\|378648\|30\|NC_022584\|CRISPRCasFinder,CRT	378648-378677	30	MN871440	UNVERIFIED: Aeromonas phage AsFcp_1, complete genome	80631-80660	8	0.733
NC_022584_2	2.9\|378648\|30\|NC_022584\|CRISPRCasFinder,CRT	378648-378677	30	NC_023688	Aeromonas phage PX29, complete genome	178934-178963	8	0.733
NC_022584_2	2.9\|378648\|30\|NC_022584\|CRISPRCasFinder,CRT	378648-378677	30	MH791407	UNVERIFIED: Aeromonas phage AsFcp_4, partial genome	83092-83121	8	0.733
NC_022584_2	2.9\|378648\|30\|NC_022584\|CRISPRCasFinder,CRT	378648-378677	30	MH791401	UNVERIFIED: Aeromonas phage AsFcp_2, complete genome	128302-128331	8	0.733
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	NZ_CP032685	Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence	913053-913082	8	0.733
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	NZ_CP032690	Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence	914052-914081	8	0.733
NC_022584_2	2.11\|378780\|30\|NC_022584\|CRISPRCasFinder,CRT	378780-378809	30	KP890823	Proteus phage vB_PmiM_Pm5461, complete genome	58908-58937	8	0.733
NC_022584_2	2.14\|378977\|31\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	378977-379007	31	NZ_CP032465	Lactobacillus plantarum strain ATG-K6 plasmid pK6, complete sequence	56401-56431	8	0.742
NC_022584_2	2.15\|379044\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379044-379073	30	NZ_CP023707	Edwardsiella tarda strain KC-Pc-HB1 plasmid pEh-Pc1, complete sequence	62676-62705	8	0.733
NC_022584_1	1.2\|232058\|30\|NC_022584\|CRT	232058-232087	30	MH238467	Pasteurella phage Pm86, complete genome	53326-53355	9	0.7
NC_022584_1	1.4\|232156\|30\|NC_022584\|CRT	232156-232185	30	MH238467	Pasteurella phage Pm86, complete genome	53326-53355	9	0.7
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	NZ_CP045274	Bacillus megaterium strain FDU301 plasmid pFDU301B, complete sequence	136778-136807	9	0.7
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	NZ_CP032528	Bacillus megaterium NCT-2 plasmid pNCT2_1, complete sequence	89791-89820	9	0.7
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	CP041518	Bacillus aryabhattai strain KNU10 plasmid unnamed2, complete sequence	41288-41317	9	0.7
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	NZ_CP041064	Bacillus megaterium strain KNU-01 plasmid pKNU_01_1, complete sequence	16844-16873	9	0.7
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	NZ_CP018876	Bacillus megaterium strain JX285 plasmid 3, complete sequence	62431-62460	9	0.7
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	KC821622	Cellulophaga phage phi46:3, complete genome	16950-16979	9	0.7
NC_022584_2	2.3\|378252\|30\|NC_022584\|CRISPRCasFinder,CRT	378252-378281	30	NC_021803	Cellulophaga phage phi13:2, complete genome	18443-18472	9	0.7
NC_022584_2	2.17\|379176\|30\|NC_022584\|CRISPRCasFinder,CRT,PILER-CR	379176-379205	30	MH572310	Microviridae sp. isolate SD_SC_21, complete genome	2734-2763	9	0.7

1. spacer 2.10|378714|30|NC_022584|CRISPRCasFinder,CRT matches to MF417967 (Uncultured Caudovirales phage clone 3S_16, partial genome) position: , mismatch: 2, identity: 0.933

gggtctttatgatagtatccatggtctgga	CRISPR spacer
gggtctttatgataatacccatggtctgga	Protospacer
**************.**.************

2. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KY065505 (Streptococcus phage IPP69, complete genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

3. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KY065456 (Streptococcus phage IPP15, complete genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

4. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KY065486 (Streptococcus phage IPP46, complete genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

5. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KY065500 (Streptococcus phage IPP64, complete genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

6. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to FR671407 (Streptococcus phage 34117) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

7. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KT337344 (Streptococcus phage phiARI0274b, partial genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

8. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NC_024361 (Streptococcus phage DCC1738, complete sequence) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

9. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KT337359 (Streptococcus phage phiARI0468b-3, partial genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

10. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KT337354 (Streptococcus phage phiARI0462, complete genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

11. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NC_031929 (Streptococcus phage phiARI0468-1, complete genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

12. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to FR671410 (Streptococcus phage 8140) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

13. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NC_024370 (Streptococcus phage IC1, complete sequence) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

14. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to FR671405 (Streptococcus phage V22) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

15. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NC_024357 (Streptococcus phage K13, complete sequence) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

16. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KT337351 (Streptococcus phage phiARI0455b, partial genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

17. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to FR671411 (Streptococcus phage 2167) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

18. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KT337362 (Streptococcus phage phiARI0598b, partial genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

19. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KT337340 (Streptococcus phage phiARI0031, complete genome) position: , mismatch: 2, identity: 0.933

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgacattaaagactggaatgt	Protospacer
 ***********.*****************

20. spacer 2.21|379440|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MF417961 (Uncultured Caudovirales phage clone 10S_15, partial genome) position: , mismatch: 2, identity: 0.933

aggacgcaagctacacgtatctccagagtt	CRISPR spacer
aggacgcaagctccacgtatctcctgagtt	Protospacer
************ *********** *****

21. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MK448904 (Streptococcus phage Javan316, complete genome) position: , mismatch: 3, identity: 0.9

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgatattaaagactggagcgt	Protospacer
 *************************..**

22. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KT337367 (Streptococcus phage phiARI0826b, partial genome) position: , mismatch: 3, identity: 0.9

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgatattaaagactggagcgt	Protospacer
 *************************..**

23. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NC_031920 (Streptococcus phage phiARI0004, complete genome) position: , mismatch: 3, identity: 0.9

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgatattaaagactggagcgt	Protospacer
 *************************..**

24. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KT337369 (Streptococcus phage phiARI0831b, partial genome) position: , mismatch: 3, identity: 0.9

aagctactgcgatattaaagactggaatgt	CRISPR spacer
tagctactgcgatattaaagactggagcgt	Protospacer
 *************************..**

25. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 4, identity: 0.867

atgaggaaagatgaatgaaaatcacacaag-	CRISPR spacer
ttgaggaaagataaatgaaaat-acataagg	Protospacer
 ***********.********* ***.***

26. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 4, identity: 0.867

atgaggaaagatgaatgaaaatcacacaag-	CRISPR spacer
ttgaggaaagataaatgaaaat-acataagg	Protospacer
 ***********.********* ***.***

27. spacer 2.13|378911|30|NC_022584|CRISPRCasFinder,CRT matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 5, identity: 0.833

caacactgacgtactgtccagccgatatct	CRISPR spacer
aagcattgacgtactgtccaaccgatatca	Protospacer
 *.**.**************.********

28. spacer 2.13|378911|30|NC_022584|CRISPRCasFinder,CRT matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 5, identity: 0.833

caacactgacgtactgtccagccgatatct	CRISPR spacer
aagcattgacgtactgtccaaccgatatca	Protospacer
 *.**.**************.********

29. spacer 2.13|378911|30|NC_022584|CRISPRCasFinder,CRT matches to MK448965 (Streptococcus phage Javan506, complete genome) position: , mismatch: 5, identity: 0.833

caacactgacgtactgtccagccgatatct	CRISPR spacer
aagcattgacgtactgtccaaccgatatca	Protospacer
 *.**.**************.********

30. spacer 2.13|378911|30|NC_022584|CRISPRCasFinder,CRT matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 5, identity: 0.833

caacactgacgtactgtccagccgatatct	CRISPR spacer
aagcattgacgtactgtccaaccgatatca	Protospacer
 *.**.**************.********

31. spacer 2.13|378911|30|NC_022584|CRISPRCasFinder,CRT matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 5, identity: 0.833

caacactgacgtactgtccagccgatatct	CRISPR spacer
aagcattgacgtactgtccaaccgatatca	Protospacer
 *.**.**************.********

32. spacer 2.13|378911|30|NC_022584|CRISPRCasFinder,CRT matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 5, identity: 0.833

caacactgacgtactgtccagccgatatct	CRISPR spacer
aagcattgacgtactgtccaaccgatatca	Protospacer
 *.**.**************.********

33. spacer 2.13|378911|30|NC_022584|CRISPRCasFinder,CRT matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 5, identity: 0.833

caacactgacgtactgtccagccgatatct	CRISPR spacer
aagcattgacgtactgtccaaccgatatca	Protospacer
 *.**.**************.********

34. spacer 2.13|378911|30|NC_022584|CRISPRCasFinder,CRT matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 5, identity: 0.833

caacactgacgtactgtccagccgatatct	CRISPR spacer
aagcattgacgtactgtccaaccgatatca	Protospacer
 *.**.**************.********

35. spacer 2.17|379176|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MG969415 (UNVERIFIED: Salmonella phage GE_vB_TR, complete genome) position: , mismatch: 5, identity: 0.833

gaaagcgtctcaggacgcttaaacgacttg	CRISPR spacer
gaaagcgtatcaggacgcttaaagaacata	Protospacer
******** ************** .** *.

36. spacer 2.17|379176|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MK448939 (Streptococcus phage Javan440, complete genome) position: , mismatch: 5, identity: 0.833

-gaaagcgtctcaggacgcttaaacgacttg	CRISPR spacer
cccaagc-tctcaggacgctcaaaagacttg	Protospacer
   **** ************.*** ******

37. spacer 2.17|379176|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MK448758 (Streptococcus phage Javan433, complete genome) position: , mismatch: 5, identity: 0.833

-gaaagcgtctcaggacgcttaaacgacttg	CRISPR spacer
cccaagc-tctcaggacgctcaaaagacttg	Protospacer
   **** ************.*** ******

38. spacer 2.17|379176|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MK448759 (Streptococcus phage Javan439, complete genome) position: , mismatch: 5, identity: 0.833

-gaaagcgtctcaggacgcttaaacgacttg	CRISPR spacer
cccaagc-tctcaggacgctcaaaagacttg	Protospacer
   **** ************.*** ******

39. spacer 2.17|379176|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to KY065498 (Streptococcus phage IPP62, complete genome) position: , mismatch: 5, identity: 0.833

-gaaagcgtctcaggacgcttaaacgacttg	CRISPR spacer
cccaagc-tctcaggacgctcaaaagacttg	Protospacer
   **** ************.*** ******

40. spacer 2.17|379176|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MK448757 (Streptococcus phage Javan427, complete genome) position: , mismatch: 5, identity: 0.833

-gaaagcgtctcaggacgcttaaacgacttg	CRISPR spacer
cccaagc-tctcaggacgctcaaaagacttg	Protospacer
   **** ************.*** ******

41. spacer 2.21|379440|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NC_008723 (Staphylococcus phage PH15, complete genome) position: , mismatch: 5, identity: 0.833

aggacgcaagctacacgtatctccagagtt	CRISPR spacer
agtttgcaagctacacatatttccagagtt	Protospacer
**  .***********.***.*********

42. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to AGRM01000007 (Salmonella enterica subsp. houtenae str. ATCC BAA-1581 plasmid pSEHO0A2, complete sequence, whole genome shotgun sequence) position: , mismatch: 6, identity: 0.8

atgaggaaagatgaatgaaaatcacacaag	CRISPR spacer
ctgaggaaaaatgaatgaaaattaccgcag	Protospacer
 ********.************.**   **

43. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP030218 (Salmonella enterica strain SA20075157 plasmid pSA20075157.1, complete sequence) position: , mismatch: 6, identity: 0.8

atgaggaaagatgaatgaaaatcacacaag	CRISPR spacer
ctgaggaaaaatgaatgaaaattaccgcag	Protospacer
 ********.************.**   **

44. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP030289 (Salmonella enterica subsp. enterica serovar Gaminara str. SA20063285 plasmid pIncI1.1, complete sequence) position: , mismatch: 6, identity: 0.8

atgaggaaagatgaatgaaaatcacacaag	CRISPR spacer
ctgaggaaaaatgaatgaaaattaccgcag	Protospacer
 ********.************.**   **

45. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP024167 (Salmonella enterica subsp. enterica serovar Gaminara strain CFSAN070644 plasmid pCFSAN024441_02, complete sequence) position: , mismatch: 6, identity: 0.8

atgaggaaagatgaatgaaaatcacacaag	CRISPR spacer
ctgaggaaaaatgaatgaaaattaccgcag	Protospacer
 ********.************.**   **

46. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to CP053410 (Salmonella enterica strain 2014K-0203 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

atgaggaaagatgaatgaaaatcacacaag	CRISPR spacer
ctgaggaaaaatgaatgaaaattaccgcag	Protospacer
 ********.************.**   **

47. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to CP053415 (Salmonella enterica strain 2011K-0868 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

atgaggaaagatgaatgaaaatcacacaag	CRISPR spacer
ctgaggaaaaatgaatgaaaattaccgcag	Protospacer
 ********.************.**   **

48. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to CP053327 (Salmonella enterica subsp. salamae serovar 58:c:z6 strain 2013K-0366 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

atgaggaaagatgaatgaaaatcacacaag	CRISPR spacer
ctgaggaaaaatgaatgaaaattaccgcag	Protospacer
 ********.************.**   **

49. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MG592448 (Vibrio phage 1.071.A._10N.286.46.A12, partial genome) position: , mismatch: 6, identity: 0.8

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaattggacgttgctgtctttgttgatat	Protospacer
*.* .****** ** **************

50. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MG592400 (Vibrio phage 1.016.O._10N.286.46.A11, partial genome) position: , mismatch: 6, identity: 0.8

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaattggacgttgctgtctttgttgatat	Protospacer
*.* .****** ** **************

51. spacer 2.19|379307|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019315 (Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-3, complete sequence) position: , mismatch: 6, identity: 0.8

---tttaacgtagctgaaagcggatgggaaagc	CRISPR spacer
cggtgcaac---gctgaaagcggatgcgaaagc	Protospacer
   * .***   ************** ******

52. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP034685 (Bacillus sp. BD59S plasmid pBTBD59S2, complete sequence) position: , mismatch: 7, identity: 0.767

atgaggaaagatgaatgaaaatcacacaag	CRISPR spacer
gagaggaaatatgaatgaaaatcagcaaat	Protospacer
. ******* **************   **

53. spacer 2.6|378450|30|NC_022584|CRISPRCasFinder,CRT matches to NC_047815 (Erwinia phage vB_EamM_Yoloswag, complete genome) position: , mismatch: 7, identity: 0.767

atgaggaaagatgaatgaaaatcacacaag	CRISPR spacer
ctgaggaataatgaatgaaaatcaatcttg	Protospacer
 ******* .**************  *  *

54. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP013579 (Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
gaacctggacgccggtgtctttgcgcaata	Protospacer
*********** .**********.  *  *

55. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP013546 (Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
gaacctggacgccggtgtctttgcgcaata	Protospacer
*********** .**********.  *  *

56. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP013573 (Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
gaacctggacgccggtgtctttgcgcaata	Protospacer
*********** .**********.  *  *

57. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MH001458 (Mycobacterium phage Smeagol, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

58. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MN369760 (Mycobacterium phage KyMonks1A, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

59. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MH371110 (Mycobacterium phage Magnar, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

60. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MH230878 (Mycobacterium phage Oogway, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

61. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MN585985 (Mycobacterium phage Watermelon, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

62. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MK061415 (Mycobacterium phage Rhynn, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

63. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to NC_022070 (Mycobacteriophage Wheeler, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

64. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MT657342 (Mycobacterium phage Mule, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

65. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MH338239 (Mycobacterium phage Mryolo, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

66. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to EU744251 (Mycobacterium phage Jasper, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

67. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to NC_023723 (Mycobacterium phage Aeneas, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

68. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to KC701493 (Mycobacterium phage CASbig, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

69. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to JN398369 (Mycobacterium phage RidgeCB, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

70. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to NC_022329 (Mycobacterium phage PhrostyMug, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

71. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to EU744249 (Mycobacterium phage Lockley, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

72. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to NC_041853 (Mycobacterium phage Marcell, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

73. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MH697575 (Mycobacterium phage Adahisdi, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

74. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to EU744252 (Mycobacterium phage DD5, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

75. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to MK359316 (Mycobacterium phage Cueylyss, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

76. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to NC_031041 (Mycobacterium phage Papez, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

77. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to KF024724 (Mycobacterium phage Trouble, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

78. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to JN699016 (Mycobacterium phage Kugel, complete genome) position: , mismatch: 7, identity: 0.767

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ggaggtggacgacggtgtctttgtcgatct	Protospacer
*.*  *******.***********.***

79. spacer 2.12|378846|29|NC_022584|CRISPRCasFinder,CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.759

atatcgtccatgtctgggataggcccgct	CRISPR spacer
ccttcgtccatgactgggataggccgtcg	Protospacer
 . ********* ************  *

80. spacer 2.14|378977|31|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015943 (Legionella pneumophila strain C9_S plasmid unamed2, complete sequence) position: , mismatch: 7, identity: 0.774

tcataaattatcaaattgaacttctcttact	CRISPR spacer
taaaccatcatcaaattcaacttctcttatt	Protospacer
* *   **.******** ***********.*

81. spacer 2.14|378977|31|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021276 (Legionella pneumophila strain D-4040 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

tcataaattatcaaattgaacttctcttact	CRISPR spacer
taaaccatcatcaaattcaacttctcttatt	Protospacer
* *   **.******** ***********.*

82. spacer 2.14|378977|31|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015952 (Legionella pneumophila strain E5_N plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

tcataaattatcaaattgaacttctcttact	CRISPR spacer
taaaccatcatcaaattcaacttctcttatt	Protospacer
* *   **.******** ***********.*

83. spacer 2.14|378977|31|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016846 (Carnobacterium maltaromaticum strain TMW 2.1581 plasmid pL21581-2, complete sequence) position: , mismatch: 7, identity: 0.774

-tcataaattatcaaattgaacttctcttact	CRISPR spacer
atcac-cgttatcaaattgaatttctattaca	Protospacer
 ***.  .*************.**** ****

84. spacer 2.14|378977|31|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MF001361 (Enterococcus phage EF5, partial genome) position: , mismatch: 7, identity: 0.774

tcataaattatcaaattgaacttctcttact	CRISPR spacer
taacagattatcaaaatgaagttctcttata	Protospacer
* *.*.********* **** ********.

85. spacer 2.14|378977|31|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021278 (Legionella pneumophila subsp. fraseri strain D-4058 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

tcataaattatcaaattgaacttctcttact	CRISPR spacer
taaaccatcatcaaattcaacttctcttatt	Protospacer
* *   **.******** ***********.*

86. spacer 2.14|378977|31|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015948 (Legionella pneumophila strain E2_N plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

tcataaattatcaaattgaacttctcttact	CRISPR spacer
taaaccatcatcaaattcaacttctcttatt	Protospacer
* *   **.******** ***********.*

87. spacer 2.14|378977|31|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MF001358 (Enterococcus phage EF1, partial genome) position: , mismatch: 7, identity: 0.774

tcataaattatcaaattgaacttctcttact	CRISPR spacer
taacagattatcaaaatgaagttctcttata	Protospacer
* *.*.********* **** ********.

88. spacer 2.16|379110|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MK448902 (Streptococcus phage Javan308, complete genome) position: , mismatch: 7, identity: 0.767

aagctactgcgatattaaagactggaatgt	CRISPR spacer
agcatactgcgaaataaaagactggaaaat	Protospacer
*.  ******** ** *********** .*

89. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP035095 (Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

taaaaatcaattcttttagatcatcactca	CRISPR spacer
atgaaagcaattcttttaaatcatcaattg	Protospacer
  .*** ***********.******* *..

90. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP040345 (Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

taaaaatcaattcttttagatcatcactca	CRISPR spacer
ctaaaattaattcttttagttcatcggttt	Protospacer
. *****.*********** *****. *.

91. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP009921 (Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid pBMV_2, complete sequence) position: , mismatch: 8, identity: 0.733

taaaaatcaattcttttagatcatcactca	CRISPR spacer
atgaaagcaattcttttaaatcatcaattg	Protospacer
  .*** ***********.******* *..

92. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to NC_016046 (Oscillibacter valericigenes Sjm18-20 plasmid pOBV01, complete sequence) position: , mismatch: 8, identity: 0.733

taaaaatcaattcttttagatcatcactca	CRISPR spacer
cagcaatcaattctcttaaatcatcacctc	Protospacer
.*. **********.***.********..

93. spacer 2.8|378582|30|NC_022584|CRISPRCasFinder,CRT matches to NC_041884 (Acinetobacter phage vB_AbaM_ME3, complete genome) position: , mismatch: 8, identity: 0.733

agagggtatttttggcagaattataaatct	CRISPR spacer
taactttatttttagcaggattataaatcg	Protospacer
 .*   *******.****.**********

94. spacer 2.9|378648|30|NC_022584|CRISPRCasFinder,CRT matches to MN871440 (UNVERIFIED: Aeromonas phage AsFcp_1, complete genome) position: , mismatch: 8, identity: 0.733

cgaaagggcaaagaatgaattgatgcgatt	CRISPR spacer
tgaaagcgcaaagaatgaattcatcaagtc	Protospacer
.***** ************** **  ..*.

95. spacer 2.9|378648|30|NC_022584|CRISPRCasFinder,CRT matches to NC_023688 (Aeromonas phage PX29, complete genome) position: , mismatch: 8, identity: 0.733

cgaaagggcaaagaatgaattgatgcgatt	CRISPR spacer
tgaaagcgcaaagaatgaattcatcaagtc	Protospacer
.***** ************** **  ..*.

96. spacer 2.9|378648|30|NC_022584|CRISPRCasFinder,CRT matches to MH791407 (UNVERIFIED: Aeromonas phage AsFcp_4, partial genome) position: , mismatch: 8, identity: 0.733

cgaaagggcaaagaatgaattgatgcgatt	CRISPR spacer
tgaaagcgcaaagaatgaattcatcaagtc	Protospacer
.***** ************** **  ..*.

97. spacer 2.9|378648|30|NC_022584|CRISPRCasFinder,CRT matches to MH791401 (UNVERIFIED: Aeromonas phage AsFcp_2, complete genome) position: , mismatch: 8, identity: 0.733

cgaaagggcaaagaatgaattgatgcgatt	CRISPR spacer
tgaaagcgcaaagaatgaattcatcaagtc	Protospacer
.***** ************** **  ..*.

98. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP032685 (Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence) position: , mismatch: 8, identity: 0.733

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
gaaccttgacgatggtgtcttttccgggct	Protospacer
****** *************** ..*.

99. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP032690 (Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence) position: , mismatch: 8, identity: 0.733

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
gaaccttgacgatggtgtcttttccgggct	Protospacer
****** *************** ..*.

100. spacer 2.11|378780|30|NC_022584|CRISPRCasFinder,CRT matches to KP890823 (Proteus phage vB_PmiM_Pm5461, complete genome) position: , mismatch: 8, identity: 0.733

gaacctggacgatggtgtctttgttgataa	CRISPR spacer
ttatttggacgatagtgtctttattgattt	Protospacer
  *..********.********.*****

101. spacer 2.14|378977|31|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032465 (Lactobacillus plantarum strain ATG-K6 plasmid pK6, complete sequence) position: , mismatch: 8, identity: 0.742

tcataaattatcaaattgaacttctcttact	CRISPR spacer
aaataacttatcatattgaacttcttcttca	Protospacer
  **** ****** ***********..* *

102. spacer 2.15|379044|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023707 (Edwardsiella tarda strain KC-Pc-HB1 plasmid pEh-Pc1, complete sequence) position: , mismatch: 8, identity: 0.733

acgttgtttctcaccacgtttcgaaccttt	CRISPR spacer
gcgttgtttctcacaacgtttcttatttaa	Protospacer
.************* *******  *..*

103. spacer 1.2|232058|30|NC_022584|CRT matches to MH238467 (Pasteurella phage Pm86, complete genome) position: , mismatch: 9, identity: 0.7

ggtcgcctagaaataaaaaagcgacccagg	CRISPR spacer
tattttctataaataaaaaagcgacccgaa	Protospacer
 .*. .*** *****************...

104. spacer 1.4|232156|30|NC_022584|CRT matches to MH238467 (Pasteurella phage Pm86, complete genome) position: , mismatch: 9, identity: 0.7

ggtcgcctagaaataaaaaagcgacccagg	CRISPR spacer
tattttctataaataaaaaagcgacccgaa	Protospacer
 .*. .*** *****************...

105. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP045274 (Bacillus megaterium strain FDU301 plasmid pFDU301B, complete sequence) position: , mismatch: 9, identity: 0.7

taaaaatcaattcttttagatcatcactca	CRISPR spacer
atgaaagcaattcttttaaatcatcaactg	Protospacer
  .*** ***********.******* ...

106. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP032528 (Bacillus megaterium NCT-2 plasmid pNCT2_1, complete sequence) position: , mismatch: 9, identity: 0.7

taaaaatcaattcttttagatcatcactca	CRISPR spacer
atgaaagcaattcttttaaatcatcaactg	Protospacer
  .*** ***********.******* ...

107. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to CP041518 (Bacillus aryabhattai strain KNU10 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

taaaaatcaattcttttagatcatcactca	CRISPR spacer
atgaaagcaattcttttaaatcatcaactg	Protospacer
  .*** ***********.******* ...

108. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP041064 (Bacillus megaterium strain KNU-01 plasmid pKNU_01_1, complete sequence) position: , mismatch: 9, identity: 0.7

taaaaatcaattcttttagatcatcactca	CRISPR spacer
atgaaagcaattcttttaaatcatcaactg	Protospacer
  .*** ***********.******* ...

109. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to NZ_CP018876 (Bacillus megaterium strain JX285 plasmid 3, complete sequence) position: , mismatch: 9, identity: 0.7

taaaaatcaattcttttagatcatcactca	CRISPR spacer
atgaaagcaattcttttaaatcatcaactg	Protospacer
  .*** ***********.******* ...

110. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to KC821622 (Cellulophaga phage phi46:3, complete genome) position: , mismatch: 9, identity: 0.7

taaaaatcaattcttttagatcatcactca	CRISPR spacer
agtcgctcaattcttttaaatcttcactcc	Protospacer
 .  . ************.*** ******

111. spacer 2.3|378252|30|NC_022584|CRISPRCasFinder,CRT matches to NC_021803 (Cellulophaga phage phi13:2, complete genome) position: , mismatch: 9, identity: 0.7

taaaaatcaattcttttagatcatcactca	CRISPR spacer
agtcgctcaattcttttaaatcttcactcc	Protospacer
 .  . ************.*** ******

112. spacer 2.17|379176|30|NC_022584|CRISPRCasFinder,CRT,PILER-CR matches to MH572310 (Microviridae sp. isolate SD_SC_21, complete genome) position: , mismatch: 9, identity: 0.7

gaaagcgtctcaggacgcttaaacgacttg	CRISPR spacer
caatgcgtctgaggacgcttaaacactaaa	Protospacer
 ** ****** *************. .  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

12421 : 20195

Streptococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023026414.1\|12421_15286_+	DEAD/DEAH box helicase	U3PFS7	Lactobacillus_phage	2.1e-24	28.7
WP_023026418.1\|15683_16076_-	(deoxy)nucleoside triphosphate pyrophosphohydrolase	NA	NA	NA	NA
WP_023026420.1\|16263_16569_-	hypothetical protein	E4ZFJ0	Streptococcus_phage	4.2e-16	46.7
WP_023026422.1\|16549_16921_-	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	1.4e-13	40.2
WP_023026424.1\|16917_18330_-	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	4.0e-178	66.5
WP_042360991.1\|18332_19010_-	helix-turn-helix transcriptional regulator	A0A1B0RXB1	Streptococcus_phage	8.0e-52	47.8
WP_042360992.1\|19192_19732_+	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_023026429.1\|19721_20195_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.1e-14	28.5

DBSCAN-SWA_2

949577 : 961575

Streptococcus_phage(64.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023027122.1\|949577_950570_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-16	29.6
WP_023027123.1\|951117_951942_+	peptidylprolyl isomerase	A0A1V0S9I2	Catovirus	3.7e-19	36.6
WP_023027124.1\|952125_953667_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	4.4e-53	27.7
WP_023027125.1\|953896_954250_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	7.9e-35	59.8
WP_023027126.1\|954259_954748_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	8.4e-35	45.2
WP_023027127.1\|954740_955313_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	8.3e-58	57.2
WP_023027128.1\|955302_956187_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.5e-111	71.5
WP_023024026.1\|956189_956510_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.8e-30	65.1
WP_023024028.1\|956514_957414_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.5e-79	52.0
WP_023024030.1\|957410_958049_-	dTMP kinase	M1PSC7	Streptococcus_phage	3.9e-72	63.6
WP_023024032.1\|958221_959109_+	YitT family protein	M1Q1P6	Streptococcus_phage	1.1e-80	51.2
WP_023024035.1\|959148_959805_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	3.5e-84	75.5
WP_003008277.1\|960100_960811_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.3e-17	28.1
WP_023024036.1\|960810_961575_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.8e-15	25.7

DBSCAN-SWA_3

1150305 : 1185530

Chrysochromulina_ericina_virus(18.18%)

protease,holin,transposase,integrase

attL 1175680:1175731|attR 1185639:1185690

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023027229.1\|1150305_1150938_-\|holin	1-alkyl-2-acetylglycerophosphocholine esterase	A0A2K9L661	Tupanvirus	4.8e-06	26.2
WP_042361230.1\|1150990_1151824_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_023027230.1\|1152073_1152949_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_123160843.1\|1153455_1154064_+	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_081697786.1\|1153994_1154882_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-66	48.1
WP_156023429.1\|1154931_1155096_+	hypothetical protein	NA	NA	NA	NA
WP_081698213.1\|1155123_1155348_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	5.6e-10	46.3
WP_023027233.1\|1155452_1157120_-	methionine ABC transporter substrate-binding protein	A0A0N9R0S5	Chrysochromulina_ericina_virus	2.8e-13	25.2
WP_023027234.1\|1157138_1158476_-	CapA family protein	A0A0N9SJ77	Staphylococcus_phage	2.5e-28	26.3
WP_023027235.1\|1158666_1159602_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_042361233.1\|1159872_1160229_-	hypothetical protein	NA	NA	NA	NA
WP_023027237.1\|1160356_1161292_-	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	5.1e-65	43.5
WP_023027239.1\|1161667_1163014_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_023027240.1\|1163258_1164401_-	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	5.6e-21	30.5
WP_023027241.1\|1164668_1165301_-	4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis protein	NA	NA	NA	NA
WP_023027242.1\|1165503_1167327_-	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.9e-132	47.1
WP_023027243.1\|1167550_1168093_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_023027244.1\|1168099_1169134_-	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_023027245.1\|1169301_1170075_-	M15 family metallopeptidase	NA	NA	NA	NA
WP_023027246.1\|1170067_1170766_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_023027247.1\|1170807_1171524_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_023027248.1\|1171657_1172995_-	PFL family protein	NA	NA	NA	NA
WP_006595627.1\|1173013_1173280_-	ACT domain-containing protein	NA	NA	NA	NA
WP_023024357.1\|1173426_1174032_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_023024359.1\|1174146_1174854_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_021154436.1\|1175312_1175516_+	CsbD family protein	NA	NA	NA	NA
1175680:1175731	attL	NA	NA	NA	NA
WP_000126416.1\|1176044_1177094_-	DUF389 domain-containing protein	NA	NA	NA	NA
WP_001253404.1\|1177090_1177414_-	two pore domain potassium channel family protein	A0A1B0Y2S3	Lactobacillus_phage	7.1e-06	40.3
WP_000397556.1\|1177427_1177769_-	hypothetical protein	NA	NA	NA	NA
WP_081698226.1\|1177693_1177996_-	DUF1211 domain-containing protein	NA	NA	NA	NA
WP_002902313.1\|1178565_1178886_-	hypothetical protein	NA	NA	NA	NA
WP_002902311.1\|1178919_1179075_-	hypothetical protein	NA	NA	NA	NA
WP_000711078.1\|1179097_1179436_-	Cd(II)/Zn(II)-sensing metalloregulatory transcriptional regulator CadX	E4ZFI8	Streptococcus_phage	1.7e-10	33.3
WP_071788354.1\|1179447_1180074_-	CadD family cadmium resistance transporter	NA	NA	NA	NA
WP_002893754.1\|1180361_1182425_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.3e-54	26.9
WP_002902306.1\|1182426_1182705_-	hypothetical protein	NA	NA	NA	NA
WP_002893757.1\|1183766_1184003_-	hypothetical protein	NA	NA	NA	NA
WP_023027249.1\|1184455_1185064_+	DUF1269 domain-containing protein	NA	NA	NA	NA
WP_002893762.1\|1185308_1185530_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
1185639:1185690	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1551675 : 1559849

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023027448.1\|1551675_1551921_+	acyl carrier protein	E3SMK8	Prochlorococcus_phage	1.6e-05	37.3
WP_023027449.1\|1552090_1552798_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D8KNF0	Synechococcus_phage	3.9e-41	39.7
WP_023027450.1\|1552849_1556575_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	3.1e-36	25.6
WP_023027451.1\|1556587_1558027_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.9e-52	33.6
WP_023027452.1\|1558272_1559295_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	4.3e-65	44.3
WP_023027453.1\|1559294_1559849_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.6e-24	36.3

DBSCAN-SWA_5

1753520 : 1816063

Staphylococcus_phage(16.67%)

protease,integrase,tRNA,bacteriocin

attL 1746896:1746911|attR 1782281:1782296

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1746896:1746911	attL	NA	NA	NA	NA
WP_023027598.1\|1753520_1754648_+\|integrase	site-specific integrase	Q9AZR0	Lactococcus_phage	6.2e-41	30.5
WP_023027599.1\|1755066_1756338_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	8.2e-98	46.8
WP_023027600.1\|1756452_1756923_+	DUF3013 family protein	NA	NA	NA	NA
WP_023027601.1\|1756940_1758014_+	peptidase M50	NA	NA	NA	NA
WP_023027602.1\|1758036_1758579_+	hypothetical protein	NA	NA	NA	NA
WP_023027603.1\|1758628_1759072_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_023027604.1\|1759058_1759532_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_156023436.1\|1759670_1760621_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_023027606.1\|1760622_1761372_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_023027607.1\|1761412_1763881_-	bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase	NA	NA	NA	NA
WP_006595074.1\|1764141_1766361_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	5.0e-10	36.5
WP_023027608.1\|1766564_1767008_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_023027609.1\|1767301_1767955_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_042361347.1\|1768095_1769121_+	DUF3114 domain-containing protein	NA	NA	NA	NA
WP_023027611.1\|1769230_1769725_-	thiol peroxidase	NA	NA	NA	NA
WP_023027612.1\|1769811_1770744_-	metal ABC transporter substrate-binding lipoprotein/fibrin-binding adhesin FimA	NA	NA	NA	NA
WP_023022124.1\|1770755_1771598_-	metal ABC transporter permease	NA	NA	NA	NA
WP_023022125.1\|1771594_1772317_-	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.6e-18	29.7
WP_023027613.1\|1772465_1774361_+	endopeptidase	E3T4I7	Cafeteria_roenbergensis_virus	9.4e-74	30.6
WP_023027615.1\|1774898_1775675_-	glycyl-radical enzyme activating protein	NA	NA	NA	NA
WP_023027616.1\|1775804_1776548_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_023027617.1\|1776562_1777534_+	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_006595062.1\|1777701_1778025_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_006595061.1\|1778035_1778347_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_006595060.1\|1778358_1779660_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_023027619.1\|1779801_1782240_+	glycyl radical protein	Q66LZ4	Escherichia_phage	9.4e-10	56.6
WP_023027620.1\|1782255_1782924_+	fructose-6-phosphate aldolase	M4QRR4	Synechococcus_phage	1.7e-22	31.0
1782281:1782296	attR	NA	NA	NA	NA
WP_042361352.1\|1782938_1784030_+	glycerol dehydrogenase	NA	NA	NA	NA
WP_006595056.1\|1784241_1784382_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_006595055.1\|1784476_1785151_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_023027622.1\|1785338_1787321_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_023027623.1\|1787605_1790107_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	66.3
WP_023027624.1\|1790231_1790945_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_023027625.1\|1791268_1791427_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_023027627.1\|1791641_1791830_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_023027629.1\|1791997_1792690_+	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_023027630.1\|1792818_1794222_+	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_023027631.1\|1794439_1795366_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_023027632.1\|1795830_1796760_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.3e-23	32.2
WP_023027633.1\|1796752_1797631_+	ABC transporter permease	NA	NA	NA	NA
WP_023027634.1\|1797894_1799706_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	3.7e-96	37.7
WP_023027635.1\|1799951_1801727_+	PTS mannitol transporter subunit IICBA	NA	NA	NA	NA
WP_042361355.1\|1801744_1803700_+	transcription antiterminator	NA	NA	NA	NA
WP_023022143.1\|1803701_1804139_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_023022144.1\|1804200_1805337_+	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_023027636.1\|1806737_1807559_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_006596959.1\|1807878_1808880_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_006595041.1\|1808898_1809099_+	hypothetical protein	NA	NA	NA	NA
WP_023027637.1\|1809198_1810200_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_023027638.1\|1810227_1811106_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_023027639.1\|1811172_1811865_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_023027640.1\|1811868_1812555_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_023027641.1\|1812574_1813339_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.7e-38	42.6
WP_023027642.1\|1813957_1816063_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	3.0e-121	38.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022584

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection