CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP019182	Salmonella enterica subsp. enterica serovar Inverness str. ATCC 10720 plasmid pATCC10720, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP019181	Salmonella enterica subsp. enterica serovar Inverness str. ATCC 10720 chromosome, complete genome	2 crisprs	cas14j,DEDDh,csa3,DinG,cas3,cas2,cas6e,cas5,cas7,cse2gr11,cas8e,WYL,PD-DExK	0	8	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP019181_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019181_1

2620571-2621211

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACA	PILER-CR

10 spacers

cas2,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP019181_1

>merge|NZ_CP019181|1|2620571-2621211|CRISPRCasFinder,CRT,PILER-CR
GTGTTTATCCCCGCTGACGCGGGGAACATTTTTCAGCCCTTGTCGACTGCGGAACGCCCCTCGGTTTATCCCCGCTGGCGCGGGGAACACGTCTGGGGACATTCACCTGCATGACCTTGAGGCCGGTTTATCCCCGCTGGCGCGGGGAACACATGCGTTACGTGCGCAATACCTCATCACTGGCCGGTTTATCCCCGCTGGCGCGGGGAACACAAGGATATAAATAAAATCAAAGATTTGAATGTCGGTTTATCCCCGCTGGCGCGGGGAACACTAAACAGCGCTGCAGCGGCGTTTAACTCTGTGCGGTTTATCCCCGCTGGCGCGGGGAACACCAAAAACATACTTGGCGACAAGCGTTTTTTCCCGGTTTATCCCCGCTGGCGCGGGGAACACACTTCATTACACGCAGGAAACCCCGCAGACTGCGGTTTATCCCCGCTGGCGCGGGGAACACTTTTACAGGATGATGTGCGGGGATTATTCAACCGGTTTATCCCCGCTGGCGCGGGGAACACGCTAATACGAATCCAGCACATATCCCGCCCGATCGGTTTATCCCCGCTGGCGCGGGGAACACAACACTCGCGAGGCGCTGGATCATTTTGTTTGCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP019181|1|1|2620571-2621211|CRISPRCasFinder
GTGTTTATCCCCGCTGACGCGGGGAACAT	TTTTCAGCCCTTGTCGACTGCGGAACGCCCCT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTGGGGACATTCACCTGCATGACCTTGAGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATGCGTTACGTGCGCAATACCTCATCACTGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AAGGATATAAATAAAATCAAAGATTTGAATGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAAACAGCGCTGCAGCGGCGTTTAACTCTGTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAAACATACTTGGCGACAAGCGTTTTTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACTTCATTACACGCAGGAAACCCCGCAGACTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTTTACAGGATGATGTGCGGGGATTATTCAAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTAATACGAATCCAGCACATATCCCGCCCGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACACTCGCGAGGCGCTGGATCATTTTGTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP019181|1|1|2620571-2621211|CRT
GTGTTTATCCCCGCTGACGCGGGGAACAT	TTTTCAGCCCTTGTCGACTGCGGAACGCCCCT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTGGGGACATTCACCTGCATGACCTTGAGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATGCGTTACGTGCGCAATACCTCATCACTGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AAGGATATAAATAAAATCAAAGATTTGAATGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAAACAGCGCTGCAGCGGCGTTTAACTCTGTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAAACATACTTGGCGACAAGCGTTTTTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACTTCATTACACGCAGGAAACCCCGCAGACTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTTTACAGGATGATGTGCGGGGATTATTCAAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTAATACGAATCCAGCACATATCCCGCCCGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACACTCGCGAGGCGCTGGATCATTTTGTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP019181|1|1|2620573-2621210|PILER-CR
GTTTATCCCCGCTGACGCGGGGAACATT	TTTCAGCCCTTGTCGACTGCGGAACGCCCCTCG
GTTTATCCCCGCTGGCGCGGGGAACACG	TCTGGGGACATTCACCTGCATGACCTTGAGGCCG
GTTTATCCCCGCTGGCGCGGGGAACACA	TGCGTTACGTGCGCAATACCTCATCACTGGCCG
GTTTATCCCCGCTGGCGCGGGGAACACA	AGGATATAAATAAAATCAAAGATTTGAATGTCG
GTTTATCCCCGCTGGCGCGGGGAACACT	AAACAGCGCTGCAGCGGCGTTTAACTCTGTGCG
GTTTATCCCCGCTGGCGCGGGGAACACC	AAAAACATACTTGGCGACAAGCGTTTTTTCCCG
GTTTATCCCCGCTGGCGCGGGGAACACA	CTTCATTACACGCAGGAAACCCCGCAGACTGCG
GTTTATCCCCGCTGGCGCGGGGAACACT	TTTACAGGATGATGTGCGGGGATTATTCAACCG
GTTTATCCCCGCTGGCGCGGGGAACACG	CTAATACGAATCCAGCACATATCCCGCCCGATCG
GTTTATCCCCGCTGGCGCGGGGAACACA	ACACTCGCGAGGCGCTGGATCATTTTGTTTGCG
GTTTATCCCCGCTGGCGCGGGGAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019181.1\|WP_001626535.1\|2631252_2631987_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP019181.1\|WP_000517480.1\|2615433_2615745_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP019181.1\|WP_001173663.1\|2616309_2616915_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP019181.1\|WP_001626527.1\|2613179_2614229_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP019181.1\|WP_000117944.1\|2624978_2625539_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP019181.1\|WP_001626536.1\|2633774_2635574_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP019181.1\|WP_023228028.1\|2632062_2633775_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP019181.1\|WP_023228030.1\|2623149_2623896_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP019181.1\|WP_000741653.1\|2614704_2615415_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP019181.1\|WP_001626532.1\|2625535_2627092_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP019181.1\|WP_001219244.1\|2614225_2614705_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP019181.1\|WP_001092256.1\|2616901_2618341_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP019181.1\|WP_001118109.1\|2615935_2616292_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP019181.1\|WP_020839115.1\|2622517_2623168_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP019181.1\|WP_001221538.1\|2612437_2613199_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP019181.1\|WP_000490481.1\|2619509_2620556_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP019181.1\|WP_000372384.1\|2618350_2619259_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP019181.1\|WP_023204590.1\|2621307_2621601_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP019181.1\|WP_000206415.1\|2623906_2624965_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP019181.1\|WP_023228029.1\|2627103_2629767_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124

Protein	Function_ID	Function_description	E-value
NZ_CP019181.1\|WP_001626535.1\|2631252_2631987_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	4.09705e-137
NZ_CP019181.1\|WP_000517480.1\|2615433_2615745_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.08865e-64
NZ_CP019181.1\|WP_001173663.1\|2616309_2616915_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	4.61291e-146
NZ_CP019181.1\|WP_001626527.1\|2613179_2614229_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP019181.1\|WP_000117944.1\|2624978_2625539_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	9.5399e-34
NZ_CP019181.1\|WP_001626536.1\|2633774_2635574_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP019181.1\|WP_023228028.1\|2632062_2633775_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP019181.1\|WP_023228030.1\|2623149_2623896_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	5.00214e-47
NZ_CP019181.1\|WP_000741653.1\|2614704_2615415_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	4.09575e-119
NZ_CP019181.1\|WP_001626532.1\|2625535_2627092_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP019181.1\|WP_001219244.1\|2614225_2614705_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.27909e-104
NZ_CP019181.1\|WP_001092256.1\|2616901_2618341_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP019181.1\|WP_001118109.1\|2615935_2616292_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	4.85353e-49
NZ_CP019181.1\|WP_020839115.1\|2622517_2623168_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	7.28128e-76
NZ_CP019181.1\|WP_001221538.1\|2612437_2613199_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.7078e-146
NZ_CP019181.1\|WP_000490481.1\|2619509_2620556_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP019181.1\|WP_000372384.1\|2618350_2619259_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP019181.1\|WP_023204590.1\|2621307_2621601_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.3037e-64
NZ_CP019181.1\|WP_000206415.1\|2623906_2624965_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	2.67517e-131
NZ_CP019181.1\|WP_023228029.1\|2627103_2629767_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0

>NZ_CP019181.1|WP_000490481.1|2619509_2620556_+|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>NZ_CP019181.1|WP_000372384.1|2618350_2619259_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>NZ_CP019181.1|WP_001092256.1|2616901_2618341_-|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>NZ_CP019181.1|WP_001173663.1|2616309_2616915_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>NZ_CP019181.1|WP_001118109.1|2615935_2616292_-|DUF3561-family-protein
MPGMVKVTGFNMRNSHNITFTRSDAFMVDDDATSAFPGAVVGFVSWLLALGIPFLLYGPNTLFFFLYTWPFFLALMPVSVIIGIALHLLVKGKILFSIMFTLLAVGALFGALFIWLLG
>NZ_CP019181.1|WP_000517480.1|2615433_2615745_-|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>NZ_CP019181.1|WP_000741653.1|2614704_2615415_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLTISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>NZ_CP019181.1|WP_001219244.1|2614225_2614705_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>NZ_CP019181.1|WP_001626527.1|2613179_2614229_-|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAVLAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>NZ_CP019181.1|WP_001221538.1|2612437_2613199_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
>NZ_CP019181.1|WP_023204590.1|2621307_2621601_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAVWLLEVRAGVYVGDTSKRIREMIWQQITQLGGCGNAVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVENQ
>NZ_CP019181.1|WP_020839115.1|2622517_2623168_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTSELSPAQLLHLVERGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQEQPAASAIFDVQTRPFAPMLSAGQTLRFNLRANPTVCKNGKRHDLLMEAKRQRKTQGDSQDIWSYQQQAALTWLARQGEQNGFTLRETSVDAYRQQQIRRGKDRQMIQFSSVDYTGVLVINEPALFLQRLAQGYGKSRAFGCGMMMIKPGDDA
>NZ_CP019181.1|WP_023228030.1|2623149_2623896_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDGEERLNAFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYTLAQLQASLQHPVFPLYLGRKSHPLALPLAPQLLEGSAADVLREAYRWYQDQFNALKLPLPGLQNECWWEGEHDGLTASKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>NZ_CP019181.1|WP_000206415.1|2623906_2624965_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNDNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITSLHKNMNKVYGQRTDTASFDVMNQQGSMEDVLDFICA
>NZ_CP019181.1|WP_000117944.1|2624978_2625539_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHDELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDGDTDNEQD
>NZ_CP019181.1|WP_001626532.1|2625535_2627092_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRLKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKSYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIWGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NZ_CP019181.1|WP_023228029.1|2627103_2629767_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERSVDIGWLHSEESCLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>NZ_CP019181.1|WP_001626535.1|2631252_2631987_-|phosphoadenosine-phosphosulfate-reductase
MSQLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRTDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP019181.1|WP_023228028.1|2632062_2633775_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKEISEHLLPRTRAYAEIWLDQEKVATTDEEPILGATYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVDTFKEEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDKWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NZ_CP019181.1|WP_001626536.1|2633774_2635574_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGAVAVTPAPEGKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRALVAAPSQSVATGSVNDIHTSPYTKDAPLAATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAQALIDLLRPLTPRLYSIASAQAEVESEVHITVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRSFMQQRAAEGVEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLSRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY

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Crispr_ID: NZ_CP019181_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019181_2

2637357-2637995

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

10 spacers

cas3,cas8e,cse2gr11,cas7,cas5

The CRISPR arrays of NZ_CP019181_2

>merge|NZ_CP019181|2|2637357-2637995|CRISPRCasFinder,CRT,PILER-CR
ACGGCTATCCTTGTTGGCGCGGGGAACACGGCTACACGCAAAAATTCCAGTCGTTGGCGCACGGTTTATCCCCGCTGGCGCGGGGAACACCCGATTAAGATCCGCAGTCTGCATCAGTAACTCGGTTTATCCCCGCTGGCGAGGGGAACACCGATTCTACGGCAACAGGCCAGGCTGCGACCGCGGTTTATCCCCGCTGGCGCGGGGAACACATGACATGACCGTGACTAGCGAGAATGTCCCACGGTTTATCCCCGCTGGCGCGGGGAACACCAGCCGTCACCCTCGGGCCTTGACGGTTCCCACGGTTTATCCCCGCTAGCGCGGGGAACACACCCGATGACGACAGCAGCTATATCTCCAGTGCGGTTTATCCCCGCTAGCGCGGGGAACACCTCAGCAGGCTGGAGGAGATGATCAAAAATGGCGGTTTATCCCCGCTGGCGCGGGGAACACGATCGCCTGGTTAAGCTGCATATAGAGATCTACGGTTTATTCCCGCTGGCGCGGGGAACACTCTGCGCAAATCTGGCCTGCTCAACCCATCTCCGGTTTATCCCCGCTGGCGCGGGGCCCCCCCCTGAGAGACGTTTGGTTGACTGAATGAAGCCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP019181|2|2|2637357-2637995|CRISPRCasFinder
ACGGCTATCCTTGTTGGCGCGGGGAACAC	GGCTACACGCAAAAATTCCAGTCGTTGGCGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCGATTAAGATCCGCAGTCTGCATCAGTAACT
CGGTTTATCCCCGCTGGCGAGGGGAACAC	CGATTCTACGGCAACAGGCCAGGCTGCGACCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATGACATGACCGTGACTAGCGAGAATGTCCCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAGCCGTCACCCTCGGGCCTTGACGGTTCCCA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ACCCGATGACGACAGCAGCTATATCTCCAGTG
CGGTTTATCCCCGCTAGCGCGGGGAACAC	CTCAGCAGGCTGGAGGAGATGATCAAAAATGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GATCGCCTGGTTAAGCTGCATATAGAGATCTA
CGGTTTATTCCCGCTGGCGCGGGGAACAC	TCTGCGCAAATCTGGCCTGCTCAACCCATCTC
CGGTTTATCCCCGCTGGCGCGGGGCCCCC	CCCTGAGAGACGTTTGGTTGACTGAATGAAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP019181|2|2|2637357-2637995|CRT
ACGGCTATCCTTGTTGGCGCGGGGAACAC	GGCTACACGCAAAAATTCCAGTCGTTGGCGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCGATTAAGATCCGCAGTCTGCATCAGTAACT
CGGTTTATCCCCGCTGGCGAGGGGAACAC	CGATTCTACGGCAACAGGCCAGGCTGCGACCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATGACATGACCGTGACTAGCGAGAATGTCCCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAGCCGTCACCCTCGGGCCTTGACGGTTCCCA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ACCCGATGACGACAGCAGCTATATCTCCAGTG
CGGTTTATCCCCGCTAGCGCGGGGAACAC	CTCAGCAGGCTGGAGGAGATGATCAAAAATGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GATCGCCTGGTTAAGCTGCATATAGAGATCTA
CGGTTTATTCCCGCTGGCGCGGGGAACAC	TCTGCGCAAATCTGGCCTGCTCAACCCATCTC
CGGTTTATCCCCGCTGGCGCGGGGCCCCC	CCCTGAGAGACGTTTGGTTGACTGAATGAAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP019181|2|2|2637418-2637995|PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCGATTAAGATCCGCAGTCTGCATCAGTAACT
CGGTTTATCCCCGCTGGCGAGGGGAACAC	CGATTCTACGGCAACAGGCCAGGCTGCGACCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATGACATGACCGTGACTAGCGAGAATGTCCCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAGCCGTCACCCTCGGGCCTTGACGGTTCCCA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ACCCGATGACGACAGCAGCTATATCTCCAGTG
CGGTTTATCCCCGCTAGCGCGGGGAACAC	CTCAGCAGGCTGGAGGAGATGATCAAAAATGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GATCGCCTGGTTAAGCTGCATATAGAGATCTA
CGGTTTATTCCCGCTGGCGCGGGGAACAC	TCTGCGCAAATCTGGCCTGCTCAACCCATCTC
CGGTTTATCCCCGCTGGCGCGGGGCCCCC	CCCTGAGAGACGTTTGGTTGACTGAATGAAGCCGGTT
TATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019181.1\|WP_001626535.1\|2631252_2631987_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP019181.1\|WP_001626536.1\|2633774_2635574_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP019181.1\|WP_000186397.1\|2648255_2651012_+\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
NZ_CP019181.1\|WP_000117944.1\|2624978_2625539_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP019181.1\|WP_000226841.1\|2644616_2646851_-\|GTP-diphosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP019181.1\|WP_023228030.1\|2623149_2623896_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP019181.1\|WP_001626532.1\|2625535_2627092_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP019181.1\|WP_000480218.1\|2644176_2644533_-\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	unknown	unknown	gnl\|CDD\|226136
NZ_CP019181.1\|WP_000206415.1\|2623906_2624965_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP019181.1\|WP_001540810.1\|2636461_2637259_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158
NZ_CP019181.1\|WP_000706477.1\|2651055_2652198_-\|glycerate-kinase	unknown	unknown	gnl\|CDD\|224840
NZ_CP019181.1\|WP_001626542.1\|2643914_2644211_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|226194
NZ_CP019181.1\|WP_023228029.1\|2627103_2629767_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP019181.1\|WP_000036734.1\|2639098_2640397_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP019181.1\|WP_001199961.1\|2638291_2638963_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP019181.1\|WP_000210451.1\|2642344_2643145_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP019181.1\|WP_023228028.1\|2632062_2633775_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP019181.1\|WP_000108313.1\|2636009_2636372_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP019181.1\|WP_000046849.1\|2646902_2648198_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP019181.1\|WP_000210863.1\|2640479_2642117_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437

Protein	Function_ID	Function_description	E-value
NZ_CP019181.1\|WP_001626535.1\|2631252_2631987_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	4.09705e-137
NZ_CP019181.1\|WP_001626536.1\|2633774_2635574_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP019181.1\|WP_000186397.1\|2648255_2651012_+\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
NZ_CP019181.1\|WP_000117944.1\|2624978_2625539_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	9.5399e-34
NZ_CP019181.1\|WP_000226841.1\|2644616_2646851_-\|GTP-diphosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP019181.1\|WP_023228030.1\|2623149_2623896_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	5.00214e-47
NZ_CP019181.1\|WP_001626532.1\|2625535_2627092_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP019181.1\|WP_000480218.1\|2644176_2644533_-\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	gnl\|CDD\|226136	COG3609, COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription].	6.12601e-20
NZ_CP019181.1\|WP_000206415.1\|2623906_2624965_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	2.67517e-131
NZ_CP019181.1\|WP_001540810.1\|2636461_2637259_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	1.65501e-102
NZ_CP019181.1\|WP_000706477.1\|2651055_2652198_-\|glycerate-kinase	gnl\|CDD\|224840	COG1929, COG1929, Glycerate kinase [Carbohydrate transport and metabolism].	0
NZ_CP019181.1\|WP_001626542.1\|2643914_2644211_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|226194	COG3668, ParE, Plasmid stabilization system protein [General function prediction only].	1.84108e-13
NZ_CP019181.1\|WP_023228029.1\|2627103_2629767_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP019181.1\|WP_000036734.1\|2639098_2640397_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP019181.1\|WP_001199961.1\|2638291_2638963_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.43874e-155
NZ_CP019181.1\|WP_000210451.1\|2642344_2643145_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	3.42454e-158
NZ_CP019181.1\|WP_023228028.1\|2632062_2633775_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP019181.1\|WP_000108313.1\|2636009_2636372_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
NZ_CP019181.1\|WP_000046849.1\|2646902_2648198_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP019181.1\|WP_000210863.1\|2640479_2642117_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0

>NZ_CP019181.1|WP_001540810.1|2636461_2637259_-|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNALAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRDPLPIGENFIWSGEIPVVAPEAYGIFGGHDAEPDSILDEGVLIYQSTKGLVIITGCGHRGIANIVRHCQNITGIKRIYALVGGFHLRCASPFTLWRVRRFLQEHKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>NZ_CP019181.1|WP_000108313.1|2636009_2636372_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>NZ_CP019181.1|WP_001626536.1|2633774_2635574_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGAVAVTPAPEGKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRALVAAPSQSVATGSVNDIHTSPYTKDAPLAATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAQALIDLLRPLTPRLYSIASAQAEVESEVHITVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRSFMQQRAAEGVEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLSRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>NZ_CP019181.1|WP_023228028.1|2632062_2633775_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKEISEHLLPRTRAYAEIWLDQEKVATTDEEPILGATYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVDTFKEEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDKWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NZ_CP019181.1|WP_001626535.1|2631252_2631987_-|phosphoadenosine-phosphosulfate-reductase
MSQLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRTDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP019181.1|WP_023228029.1|2627103_2629767_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERSVDIGWLHSEESCLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>NZ_CP019181.1|WP_001626532.1|2625535_2627092_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRLKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKSYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIWGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NZ_CP019181.1|WP_000117944.1|2624978_2625539_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHDELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDGDTDNEQD
>NZ_CP019181.1|WP_000206415.1|2623906_2624965_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNDNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITSLHKNMNKVYGQRTDTASFDVMNQQGSMEDVLDFICA
>NZ_CP019181.1|WP_023228030.1|2623149_2623896_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDGEERLNAFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYTLAQLQASLQHPVFPLYLGRKSHPLALPLAPQLLEGSAADVLREAYRWYQDQFNALKLPLPGLQNECWWEGEHDGLTASKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>NZ_CP019181.1|WP_001199961.1|2638291_2638963_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMPLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP019181.1|WP_000036734.1|2639098_2640397_-|phosphopyruvate-hydratase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP019181.1|WP_000210863.1|2640479_2642117_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
>NZ_CP019181.1|WP_000210451.1|2642344_2643145_-|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>NZ_CP019181.1|WP_001626542.1|2643914_2644211_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MRTVKLTPKASEDLENIWHYGWQHFGEIQADRYINHLSEIFSIMSANNIGTPRPELGEYIYALPFKRHIIYFIQSVTEVIVIRILSQNQDAGKHVNWL
>NZ_CP019181.1|WP_000480218.1|2644176_2644533_-|type-II-toxin-antitoxin-system-ParD-family-antitoxin
MFLTYISFPVYSYVRFILTVEAVMARTMTVDLGDELREFIESLIESGDYRTQSEVIRESLRLLREKQAESRLQALRELLAEGLNSGEPQAWEKDAFLRKVKTGMIKPDENGKINAKGQ
>NZ_CP019181.1|WP_000226841.1|2644616_2646851_-|GTP-diphosphokinase
MVAVRSAHINKAGEFDPKKWIASLGISSQQSCERLAETWAYCLQQTQGHPDADLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSIVTLIHGVRDMAAIRQLNATHNDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKEAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPAEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKNEGVQAEVYGRPKHIYSIWRKMQKKHLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAASGGVRSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQVEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELAHLGISLKEAEKHLLPRYNFNELEELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKTYAPQNRRKDDGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVEAVWGESYSAGYSLVVRVQANDRSGLLRDITTILANEKVNVLGVASRSDIKQQIATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGG
>NZ_CP019181.1|WP_000046849.1|2646902_2648198_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRVTTRQIITVKVNDLDSFGQGVARHNGKALFIPGLLPEESAEVIITEDKKQFARARVSRRLNDSPERETPRCPHFGVCGGCQQQHVSIALQQRSKSAALARLMKHEVNDIIAGAPWGYRRRARLSLNCPPDKPLQMGFRKAGSSDIVNVEQCPVLAPQLAALLPRIRACLASLHGTRHLGHVELVQAGSGTLMILRHTAPLSAADKEKLERFSHSEGLSLFLAPFSEILETVSGEAPWYDSHGLRLAFSPRDFIQVNEAVNQQMVARALEWLDVRAEDRVLDLFCGMGNFTLPLATRAASVIGVEGVPALVEKGRENAIRNGLHNVTFFHENLEEDVTKQPWAKNGFDKVLLDPARAGATGVMRHIIKLKPIRIVYVSCNPATLARDSEALVNAGYEVTRLAMLDMFPHTGHLESMVLFERM
>NZ_CP019181.1|WP_000186397.1|2648255_2651012_+|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSSEYGMNLQNRESIGQLISVLHRRHSDIVRAISVYDDHNRLFVTSNFHLDPSQMQLPAGAPFPRRLSVDRHGDIMILRTPIISESYSPDESAIADAKNTKNMLGYVALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELNPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRNTLDEVVTLLAHSSHDKGLELTLNIKNDVPDNVIGDPLRLQQVITNLVGNAIKFTESGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNVIIDGPSTACLAGKRLAYIEPNATAAQCTLDLLSDTPVEVVYSPTFSALPLAHYDIMILSVPVTFREPLTMQHERLAKAASMTDFLLLALPCHAQINAEKLKQGGAAACLLKPLTSTRLLPALTEYCQLNHHPEPLLMDTSKITMTVMAVDDNPANLKLIGALLEDKVQHVELCDSGHQAVDRAKQMQFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLSAGMNDYLAKPIEEEKLHNLLLRYKPGANVAARLMAPEPAEFIFNPNATLDWQLALRQAAGKPDLARDMLQMLIDFLPEVRNKIEEQLVGENPNGLVDLVHKLHGSCGYSGVPRMKNLCQLIEQQLRSGVHEEELEPEFLELLDEMDNVAREAKKILG
>NZ_CP019181.1|WP_000706477.1|2651055_2652198_-|glycerate-kinase
MKIVIAPDSYKESLSALEVATAIEQGFREIWPDADYLKLPLADGGEGTVEAMVEATAGRIVHVEVTGPLGHRVNAFYGLSGDARSAFIEMAAASGLEQVPPAQRDPLKTTSWGTGELIRHALDAGVEHIIIGIGGSATNDGGAGMVQALGARLRDAQGNDIAQGGIGLETLASIDISGLDKRLSACHIEVACDVTNPLTGKEGASAVFGPQKGATPEMIERLDTALTRYAHLIARDLHVDVLDLAGGGAAGGMGAALYAFCGAQLRRGIEIVTDALHLEACLADADLVITGEGRIDSQTIHGKVPIGVANIAKRYNKPVIGIAGSLTADVGVVHEHGLDAVFSVIYTICTLEDALKNASENVRMTARNVAATLKAGQQLR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NZ_CP022446	Bacillus cereus C1L plasmid pC1L1, complete sequence	365617-365648	7	0.781
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NZ_CP010090	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence	292734-292765	7	0.781
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	MK893987	Staphylococcus phage PMBT8, complete genome	46598-46629	7	0.781
NZ_CP019181_2	2.8\|2637813\|32\|NZ_CP019181\|CRISPRCasFinder,CRT,PILER-CR	2637813-2637844	32	NC_008275	Pseudomonas putida MT53 plasmid pWW53, complete sequence	31076-31107	7	0.781
NZ_CP019181_2	2.8\|2637813\|32\|NZ_CP019181\|CRISPRCasFinder,CRT,PILER-CR	2637813-2637844	32	MN583270	Pseudomonas aeruginosa strain NK546 plasmid pNK546b, complete sequence	186720-186751	7	0.781
NZ_CP019181_2	2.8\|2637813\|32\|NZ_CP019181\|CRISPRCasFinder,CRT,PILER-CR	2637813-2637844	32	NZ_MF144194	Pseudomonas aeruginosa strain 1160 plasmid p1160-VIM, complete sequence	62119-62150	7	0.781
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NZ_CP053689	Arthrobacter citreus strain NEB 577 plasmid unnamed1, complete sequence	123288-123319	8	0.75
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NZ_CP016536	Planococcus antarcticus DSM 14505 plasmid pPA05-2, complete sequence	3251-3282	8	0.75
NZ_CP019181_1	1.14\|2620785\|33\|NZ_CP019181\|PILER-CR	2620785-2620817	33	NZ_CP022446	Bacillus cereus C1L plasmid pC1L1, complete sequence	365616-365648	8	0.758
NZ_CP019181_1	1.14\|2620785\|33\|NZ_CP019181\|PILER-CR	2620785-2620817	33	NZ_CP010090	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence	292733-292765	8	0.758
NZ_CP019181_2	2.3\|2637508\|32\|NZ_CP019181\|CRISPRCasFinder,CRT,PILER-CR	2637508-2637539	32	MN694003	Marine virus AFVG_250M677, complete genome	17629-17660	8	0.75
NZ_CP019181_2	2.7\|2637752\|32\|NZ_CP019181\|CRISPRCasFinder,CRT,PILER-CR	2637752-2637783	32	NZ_CP049914	Vibrio sp. HDW18 plasmid p_unnamed1, complete sequence	234396-234427	8	0.75
NZ_CP019181_2	2.7\|2637752\|32\|NZ_CP019181\|CRISPRCasFinder,CRT,PILER-CR	2637752-2637783	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	85616-85647	8	0.75
NZ_CP019181_2	2.8\|2637813\|32\|NZ_CP019181\|CRISPRCasFinder,CRT,PILER-CR	2637813-2637844	32	NZ_CP029091	Pseudomonas aeruginosa strain AR441 plasmid unnamed1, complete sequence	63838-63869	8	0.75
NZ_CP019181_2	2.8\|2637813\|32\|NZ_CP019181\|CRISPRCasFinder,CRT,PILER-CR	2637813-2637844	32	NZ_CP027167	Pseudomonas aeruginosa strain AR_0356 plasmid unnamed3, complete sequence	50960-50991	8	0.75
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NZ_KJ776585	Clostridium botulinum strain DB2 plasmid pDB2, complete sequence	26482-26513	9	0.719
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NZ_KJ776583	Clostridium botulinum strain KapchunkaB3 plasmid pKAPB3, complete sequence	26491-26522	9	0.719
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NZ_KJ776579	Clostridium botulinum strain KapchunkaB2 plasmid pKAPB2, complete sequence	26491-26522	9	0.719
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NC_048073	Escherichia phage FEC19, complete genome	2173-2204	9	0.719
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NZ_LR134428	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 19	127957-127988	9	0.719
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NC_004811	Flavobacterium psychrophilum strain D12 plasmid pCP1, complete sequence	495-526	9	0.719
NZ_CP019181_1	1.5\|2620845\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620845-2620876	32	MF140428	Mycobacterium phage Slimphazie, complete genome	51491-51522	9	0.719
NZ_CP019181_1	1.5\|2620845\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620845-2620876	32	MN234231	Mycobacterium phage Rapunzel97, complete genome	51491-51522	9	0.719
NZ_CP019181_1	1.5\|2620845\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620845-2620876	32	NC_023747	Mycobacterium phage BarrelRoll, complete genome	51476-51507	9	0.719
NZ_CP019181_1	1.5\|2620845\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620845-2620876	32	MH513977	Mycobacterium phage Mynx, complete genome	51819-51850	9	0.719
NZ_CP019181_1	1.1\|2620600\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620600-2620631	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1151729-1151760	10	0.688
NZ_CP019181_1	1.1\|2620600\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620600-2620631	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	661429-661460	10	0.688
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NZ_CP030008	Enterobacter hormaechei subsp. xiangfangensis strain Pb204 plasmid pPb204001, complete sequence	1302-1333	10	0.688
NZ_CP019181_1	1.4\|2620784\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620784-2620815	32	NC_019726	Staphylococcus phage JD007, complete genome	57234-57265	10	0.688
NZ_CP019181_1	1.14\|2620785\|33\|NZ_CP019181\|PILER-CR	2620785-2620817	33	NZ_KJ776585	Clostridium botulinum strain DB2 plasmid pDB2, complete sequence	26481-26513	10	0.697
NZ_CP019181_1	1.14\|2620785\|33\|NZ_CP019181\|PILER-CR	2620785-2620817	33	NZ_KJ776583	Clostridium botulinum strain KapchunkaB3 plasmid pKAPB3, complete sequence	26490-26522	10	0.697
NZ_CP019181_1	1.14\|2620785\|33\|NZ_CP019181\|PILER-CR	2620785-2620817	33	NZ_KJ776579	Clostridium botulinum strain KapchunkaB2 plasmid pKAPB2, complete sequence	26490-26522	10	0.697
NZ_CP019181_1	1.14\|2620785\|33\|NZ_CP019181\|PILER-CR	2620785-2620817	33	NC_048073	Escherichia phage FEC19, complete genome	2173-2205	10	0.697
NZ_CP019181_2	2.8\|2637813\|32\|NZ_CP019181\|CRISPRCasFinder,CRT,PILER-CR	2637813-2637844	32	NZ_CP007453	Peptoclostridium acidaminophilum DSM 3953 strain al-2 plasmid EAL2_808p, complete sequence	355417-355448	10	0.688
NZ_CP019181_2	2.8\|2637813\|32\|NZ_CP019181\|CRISPRCasFinder,CRT,PILER-CR	2637813-2637844	32	MT410774	Psychrobacillus phage Spoks, complete genome	30389-30420	10	0.688
NZ_CP019181_1	1.7\|2620967\|32\|NZ_CP019181\|CRISPRCasFinder,CRT	2620967-2620998	32	NZ_CP049817	Monaibacterium sp. ALG8 plasmid unnamed6, complete sequence	60899-60930	11	0.656

1. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NZ_CP022446 (Bacillus cereus C1L plasmid pC1L1, complete sequence) position: , mismatch: 7, identity: 0.781

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
tcagctataaataatatcaaagatttcaatga	Protospacer
  .* ********* *********** ****

2. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NZ_CP010090 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence) position: , mismatch: 7, identity: 0.781

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
tcagctataaataatatcaaagatttcaatga	Protospacer
  .* ********* *********** ****

3. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to MK893987 (Staphylococcus phage PMBT8, complete genome) position: , mismatch: 7, identity: 0.781

aaggatataaataaaatcaaagatttgaatgt----	CRISPR spacer
aagaatataaataacatcaaaga----aaagttaga	Protospacer
***.********** ********    ** **

4. spacer 2.8|2637813|32|NZ_CP019181|CRISPRCasFinder,CRT,PILER-CR matches to NC_008275 (Pseudomonas putida MT53 plasmid pWW53, complete sequence) position: , mismatch: 7, identity: 0.781

gatcgcctggttaagctgcatatagagatcta	CRISPR spacer
gagttgctggtgaagctgcatatacagatcga	Protospacer
** .  ***** ************ ***** *

5. spacer 2.8|2637813|32|NZ_CP019181|CRISPRCasFinder,CRT,PILER-CR matches to MN583270 (Pseudomonas aeruginosa strain NK546 plasmid pNK546b, complete sequence) position: , mismatch: 7, identity: 0.781

gatcgcctggttaagctgcatatagagatcta	CRISPR spacer
gagttgctggtgaagctgcatatacagatcga	Protospacer
** .  ***** ************ ***** *

6. spacer 2.8|2637813|32|NZ_CP019181|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MF144194 (Pseudomonas aeruginosa strain 1160 plasmid p1160-VIM, complete sequence) position: , mismatch: 7, identity: 0.781

gatcgcctggttaagctgcatatagagatcta	CRISPR spacer
gagttgctggtcaagctgcatatacagatcga	Protospacer
** .  *****.************ ***** *

7. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NZ_CP053689 (Arthrobacter citreus strain NEB 577 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
gaagttataaataaaatcaaaaattcgataat	Protospacer
.*.* ****************.***.**  .*

8. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NZ_CP016536 (Planococcus antarcticus DSM 14505 plasmid pPA05-2, complete sequence) position: , mismatch: 8, identity: 0.75

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
agcgaacgcaatgaaatcaaggatttgaatgt	Protospacer
*. **    ***.*******.***********

9. spacer 1.14|2620785|33|NZ_CP019181|PILER-CR matches to NZ_CP022446 (Bacillus cereus C1L plasmid pC1L1, complete sequence) position: , mismatch: 8, identity: 0.758

caaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
atcagctataaataatatcaaagatttcaatga	Protospacer
   .* ********* *********** ****

10. spacer 1.14|2620785|33|NZ_CP019181|PILER-CR matches to NZ_CP010090 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence) position: , mismatch: 8, identity: 0.758

caaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
atcagctataaataatatcaaagatttcaatga	Protospacer
   .* ********* *********** ****

11. spacer 2.3|2637508|32|NZ_CP019181|CRISPRCasFinder,CRT,PILER-CR matches to MN694003 (Marine virus AFVG_250M677, complete genome) position: , mismatch: 8, identity: 0.75

cgattctacggcaacaggccaggctgcgaccg	CRISPR spacer
ggcgagcacggcaacagcccaggctgcgatcg	Protospacer
 *    .********** ***********.**

12. spacer 2.7|2637752|32|NZ_CP019181|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049914 (Vibrio sp. HDW18 plasmid p_unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ctcagcaggctggaggagatgatcaaaaatgg----	CRISPR spacer
ctcagcaggctggaagagacgatc----gtgttacc	Protospacer
**************.****.****    .**

13. spacer 2.7|2637752|32|NZ_CP019181|CRISPRCasFinder,CRT,PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 8, identity: 0.75

ctcagcaggctggaggagatgatcaaaaatgg	CRISPR spacer
atgataaggctggaagagatgaacaaaaatta	Protospacer
 * *  ********.******* ******* .

14. spacer 2.8|2637813|32|NZ_CP019181|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029091 (Pseudomonas aeruginosa strain AR441 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gatcgcctggttaagctgcatatagagatcta	CRISPR spacer
gagttgctggtgaagctgcatatacagattga	Protospacer
** .  ***** ************ ****. *

15. spacer 2.8|2637813|32|NZ_CP019181|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027167 (Pseudomonas aeruginosa strain AR_0356 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.75

gatcgcctggttaagctgcatatagagatcta	CRISPR spacer
gagttgctggtgaagctgcatatacagattga	Protospacer
** .  ***** ************ ****. *

16. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NZ_KJ776585 (Clostridium botulinum strain DB2 plasmid pDB2, complete sequence) position: , mismatch: 9, identity: 0.719

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
aaggatataaataaaattaaaaatgcaatgag	Protospacer
*****************.***.** ..*  .

17. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NZ_KJ776583 (Clostridium botulinum strain KapchunkaB3 plasmid pKAPB3, complete sequence) position: , mismatch: 9, identity: 0.719

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
aaggatataaataaaattaaaaatgcaatgag	Protospacer
*****************.***.** ..*  .

18. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NZ_KJ776579 (Clostridium botulinum strain KapchunkaB2 plasmid pKAPB2, complete sequence) position: , mismatch: 9, identity: 0.719

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
aaggatataaataaaattaaaaatgcaatgag	Protospacer
*****************.***.** ..*  .

19. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NC_048073 (Escherichia phage FEC19, complete genome) position: , mismatch: 9, identity: 0.719

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
taagatataaataaaaacaaagacttgcggcg	Protospacer
 *.************* ******.*** .

20. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NZ_LR134428 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 19) position: , mismatch: 9, identity: 0.719

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
atcgataaaaataaaatcaaagcttttttctt	Protospacer
*  **** ************** ***   . *

21. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NC_004811 (Flavobacterium psychrophilum strain D12 plasmid pCP1, complete sequence) position: , mismatch: 9, identity: 0.719

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
gaataattaaattaaatcgaagatttgaatta	Protospacer
.*. *  ***** *****.***********

22. spacer 1.5|2620845|32|NZ_CP019181|CRISPRCasFinder,CRT matches to MF140428 (Mycobacterium phage Slimphazie, complete genome) position: , mismatch: 9, identity: 0.719

taaacagcgctgcagcggcgtttaactctgtg	CRISPR spacer
tgttcagcgcggcagcggcgttgaacttgcgg	Protospacer
*.  ****** *********** ****.   *

23. spacer 1.5|2620845|32|NZ_CP019181|CRISPRCasFinder,CRT matches to MN234231 (Mycobacterium phage Rapunzel97, complete genome) position: , mismatch: 9, identity: 0.719

taaacagcgctgcagcggcgtttaactctgtg	CRISPR spacer
tgttcagcgcggcagcggcgttgaacttgcgg	Protospacer
*.  ****** *********** ****.   *

24. spacer 1.5|2620845|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NC_023747 (Mycobacterium phage BarrelRoll, complete genome) position: , mismatch: 9, identity: 0.719

taaacagcgctgcagcggcgtttaactctgtg	CRISPR spacer
tgttcagcgcggcagcggcgttgaacttgcgg	Protospacer
*.  ****** *********** ****.   *

25. spacer 1.5|2620845|32|NZ_CP019181|CRISPRCasFinder,CRT matches to MH513977 (Mycobacterium phage Mynx, complete genome) position: , mismatch: 9, identity: 0.719

taaacagcgctgcagcggcgtttaactctgtg	CRISPR spacer
tgttcagcgcggcagcggcgttgaacttgcgg	Protospacer
*.  ****** *********** ****.   *

26. spacer 1.1|2620600|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 10, identity: 0.688

ttttcagcccttgtcgactgcggaacgcccct	CRISPR spacer
tccctcaccctcgtcgactgcggaccgcccgg	Protospacer
*.... .****.************ *****

27. spacer 1.1|2620600|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 10, identity: 0.688

ttttcagcccttgtcgactgcggaacgcccct	CRISPR spacer
tccctcaccctcgtcgactgcggaccgcccgg	Protospacer
*.... .****.************ *****

28. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NZ_CP030008 (Enterobacter hormaechei subsp. xiangfangensis strain Pb204 plasmid pPb204001, complete sequence) position: , mismatch: 10, identity: 0.688

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
cagaatagaaataaaatcaaagataatagaac	Protospacer
 **.*** ****************   *. ..

29. spacer 1.4|2620784|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NC_019726 (Staphylococcus phage JD007, complete genome) position: , mismatch: 10, identity: 0.688

aaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
tgagatataattaaaatcaaagaatttgaaac	Protospacer
 ..******* ************ ** .* ..

30. spacer 1.14|2620785|33|NZ_CP019181|PILER-CR matches to NZ_KJ776585 (Clostridium botulinum strain DB2 plasmid pDB2, complete sequence) position: , mismatch: 10, identity: 0.697

caaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
taaggatataaataaaattaaaaatgcaatgag	Protospacer
.*****************.***.** ..*  .

31. spacer 1.14|2620785|33|NZ_CP019181|PILER-CR matches to NZ_KJ776583 (Clostridium botulinum strain KapchunkaB3 plasmid pKAPB3, complete sequence) position: , mismatch: 10, identity: 0.697

caaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
taaggatataaataaaattaaaaatgcaatgag	Protospacer
.*****************.***.** ..*  .

32. spacer 1.14|2620785|33|NZ_CP019181|PILER-CR matches to NZ_KJ776579 (Clostridium botulinum strain KapchunkaB2 plasmid pKAPB2, complete sequence) position: , mismatch: 10, identity: 0.697

caaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
taaggatataaataaaattaaaaatgcaatgag	Protospacer
.*****************.***.** ..*  .

33. spacer 1.14|2620785|33|NZ_CP019181|PILER-CR matches to NC_048073 (Escherichia phage FEC19, complete genome) position: , mismatch: 10, identity: 0.697

caaggatataaataaaatcaaagatttgaatgt	CRISPR spacer
gtaagatataaataaaaacaaagacttgcggcg	Protospacer
  *.************* ******.*** .

34. spacer 2.8|2637813|32|NZ_CP019181|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007453 (Peptoclostridium acidaminophilum DSM 3953 strain al-2 plasmid EAL2_808p, complete sequence) position: , mismatch: 10, identity: 0.688

gatcgcctggttaagctgcatatagagatcta	CRISPR spacer
attgtcctggataagctgcttatagagaggat	Protospacer
. *  ***** ******** ********

35. spacer 2.8|2637813|32|NZ_CP019181|CRISPRCasFinder,CRT,PILER-CR matches to MT410774 (Psychrobacillus phage Spoks, complete genome) position: , mismatch: 10, identity: 0.688

gatcgcctggttaagctgcatatagagatcta	CRISPR spacer
atccatgcggttatgctgcatatagagttctg	Protospacer
. .*.. .***** ************* ***.

36. spacer 1.7|2620967|32|NZ_CP019181|CRISPRCasFinder,CRT matches to NZ_CP049817 (Monaibacterium sp. ALG8 plasmid unnamed6, complete sequence) position: , mismatch: 11, identity: 0.656

acttcattacacgcaggaaaccccgcagactg	CRISPR spacer
caccgattacgcgcaggaaaacccgcaggtga	Protospacer
  .. *****.********* *******.. .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

460978 : 566528

101

Vibrio_phage(19.23%)

tRNA,terminase,protease,tail,integrase,plate,holin,portal

attL 493575:493591|attR 570449:570465

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001285165.1\|460978_461926_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	8.4e-07	35.9
WP_000114987.1\|461941_462451_-	peptide deformylase	E3SLL2	Synechococcus_phage	6.7e-19	41.1
WP_023228063.1\|462582_463707_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_000460663.1\|463678_464152_+	DUF494 domain-containing protein	NA	NA	NA	NA
WP_001129708.1\|464178_464721_+	DNA topoisomerase	NA	NA	NA	NA
WP_001063613.1\|464725_465298_+	L-threonylcarbamoyladenylate synthase type 1 TsaC	A0A291ATS8	Pandoravirus	9.9e-11	27.3
WP_000451202.1\|465302_466121_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_001070571.1\|466117_466375_+	DUF1488 domain-containing protein	NA	NA	NA	NA
WP_001626875.1\|466350_466905_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_000795911.1\|467018_467171_+	hypothetical protein	NA	NA	NA	NA
WP_000825645.1\|473537_473759_-	membrane protein	NA	NA	NA	NA
WP_001273283.1\|473995_477109_-	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_000160383.1\|477120_478278_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_001085718.1\|478691_479354_+	acrEF/envCD operon transcriptional regulator	NA	NA	NA	NA
WP_023228466.1\|479356_481456_-	bifunctional diguanylate cyclase/phosphodiesterase	G3MA91	Bacillus_virus	7.1e-22	33.5
WP_000620015.1\|481606_481771_-	DUF2556 family protein	NA	NA	NA	NA
WP_000642611.1\|481853_482738_-	adenine-specific DNA-methyltransferase	M4QNN5	Ostreococcus_lucimarinus_virus	1.3e-25	32.8
WP_023228467.1\|483201_484428_+\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	5.9e-154	61.0
WP_023228468.1\|484427_485078_+	hypothetical protein	NA	NA	NA	NA
WP_023228469.1\|485688_485973_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_023228470.1\|485993_486644_+	hypothetical protein	A0A0P0J0J7	Acinetobacter_phage	1.4e-21	47.9
WP_023228471.1\|486708_486894_-	hypothetical protein	NA	NA	NA	NA
WP_023228472.1\|487081_487354_+	host cell division inhibitor Icd-like protein	NA	NA	NA	NA
WP_023228473.1\|487515_487914_+	DNA primase	A0A286SGR4	Klebsiella_phage	1.1e-11	54.2
WP_023228475.1\|488069_488297_+	hypothetical protein	NA	NA	NA	NA
WP_023228476.1\|488289_488643_+	hypothetical protein	NA	NA	NA	NA
WP_023228477.1\|488635_489388_+	hypothetical protein	A0A0P0ZD96	Stx2-converting_phage	2.1e-29	76.7
WP_023228478.1\|489384_489690_+	hypothetical protein	NA	NA	NA	NA
WP_023228479.1\|489779_490163_+	hypothetical protein	NA	NA	NA	NA
WP_023228480.1\|490155_490803_+	hypothetical protein	A0A286S1S7	Klebsiella_phage	3.6e-33	39.0
WP_023228481.1\|490813_492955_+	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	1.5e-192	57.4
WP_023228482.1\|492951_493347_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_023228483.1\|493390_494383_+	hypothetical protein	A0A1B5FPA6	Escherichia_phage	6.0e-72	52.1
493575:493591	attL	NA	NA	NA	NA
WP_070793455.1\|494467_495304_+	antitermination protein	A0A1B5FPA5	Escherichia_phage	6.7e-125	83.3
WP_071604142.1\|496265_496820_+	hypothetical protein	A0A0U2KD26	Escherichia_phage	3.0e-49	64.5
WP_023228137.1\|496746_497172_+	subtilase	NA	NA	NA	NA
WP_001623349.1\|497483_497873_+	hypothetical protein	K7PHB9	Enterobacterial_phage	1.1e-40	71.8
WP_023228136.1\|497859_498141_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	1.3e-35	79.6
WP_023228135.1\|498140_498767_+	glycoside hydrolase family 19 protein	Q858F0	Salmonella_phage	1.3e-91	78.3
WP_023228134.1\|498763_499306_+	DUF2514 domain-containing protein	NA	NA	NA	NA
WP_023136440.1\|499408_499912_+	hypothetical protein	NA	NA	NA	NA
WP_024148291.1\|500184_500901_+	hypothetical protein	NA	NA	NA	NA
WP_001623372.1\|501409_502000_+	ParB N-terminal domain-containing protein	A0A067ZI74	Vibrio_phage	1.5e-38	56.5
WP_024148290.1\|501999_502551_+	hypothetical protein	A0A067ZIZ9	Vibrio_phage	1.6e-18	38.2
WP_023228132.1\|502556_504416_+\|terminase	phage terminase large subunit family protein	A0A059WKL6	Vibrio_phage	1.3e-232	63.7
WP_021000635.1\|504427_504667_+	hypothetical protein	A0A067ZJ01	Vibrio_phage	6.8e-14	54.8
WP_023228131.1\|504663_506226_+\|portal	phage portal protein	A0A067ZJA4	Vibrio_phage	1.8e-187	64.3
WP_001623382.1\|506218_507283_+\|protease	Clp protease ClpP	A0A067ZG37	Vibrio_phage	1.7e-80	48.6
WP_001623384.1\|507293_507680_+	hypothetical protein	NA	NA	NA	NA
WP_076018216.1\|508734_509040_+	hypothetical protein	NA	NA	NA	NA
WP_001623387.1\|509200_509545_+	hypothetical protein	A0A067ZJA6	Vibrio_phage	1.0e-18	43.9
WP_021000628.1\|509541_510027_+	hypothetical protein	A0A067ZIL8	Vibrio_phage	8.4e-19	36.0
WP_001623389.1\|510026_510326_+	hypothetical protein	NA	NA	NA	NA
WP_076018217.1\|512877_513294_+	hypothetical protein	NA	NA	NA	NA
WP_001623395.1\|515235_515454_+	hypothetical protein	A0A0C5AEF4	Bacteriophage	3.2e-10	50.0
WP_001623396.1\|515443_516445_+	phage late control D	A0A0C5AJ59	Bacteriophage	1.8e-55	36.3
WP_001623397.1\|516445_517066_+\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	1.3e-32	55.9
WP_001623398.1\|517062_517530_+\|tail	phage tail protein	NA	NA	NA	NA
WP_021000619.1\|517526_517850_+	hypothetical protein	A0A067ZJ13	Vibrio_phage	6.0e-13	41.3
WP_023228127.1\|517846_518971_+\|plate	baseplate J/gp47 family protein	A0A0C5AEG2	Bacteriophage	3.0e-88	43.9
WP_023228126.1\|518963_519545_+\|tail	phage tail protein I	V9IQK7	Stenotrophomonas_phage	7.7e-19	34.1
WP_149866814.1\|520475_521795_+\|tail	phage tail protein	Q8HAB4	Salmonella_phage	3.8e-183	79.6
WP_023228124.1\|521807_522338_+\|tail	tail fiber assembly protein	S4TUB9	Salmonella_phage	4.3e-93	97.1
WP_024148288.1\|523284_523710_+	subtilase	NA	NA	NA	NA
WP_001623421.1\|523725_524457_+	pertussis-like toxin subunit ArtA	A0A0U2KD26	Escherichia_phage	1.9e-59	51.2
WP_023228121.1\|524657_525200_+	glycoside hydrolase family 108 protein	A0A0U2S643	Escherichia_phage	4.0e-70	65.4
WP_023228120.1\|525376_525742_-	DUF1353 domain-containing protein	I1TQ41	Pseudomonas_phage	9.4e-15	38.2
WP_001623424.1\|525902_526712_-	cytolethal distending toxin subunit B family protein	A5LH53	Enterobacteria_phage	1.6e-59	47.0
WP_001623427.1\|527409_527634_-	DinI family protein	K7PKR6	Enterobacteria_phage	3.8e-27	88.6
WP_001160725.1\|527962_528286_+	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_000645852.1\|528282_529113_+	N-acetylmuramoyl-L-alanine amidase	A0A1B0UZW5	Roseobacter_phage	1.3e-08	30.7
WP_000866905.1\|529109_530123_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_023228157.1\|530218_531652_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000566347.1\|531662_532664_-	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_001623438.1\|532702_534421_-	ubiquinone-dependent pyruvate dehydrogenase	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	1.3e-29	24.4
WP_023210713.1\|534578_535547_-	NADH oxidoreductase	NA	NA	NA	NA
WP_000458785.1\|535558_537211_-	hydroxylamine reductase	NA	NA	NA	NA
WP_001623439.1\|537354_538254_-	lysine exporter LysO family protein	NA	NA	NA	NA
WP_000599763.1\|538455_540114_+	ATP-dependent endonuclease	NA	NA	NA	NA
WP_001617140.1\|540110_541061_-	VirK/YbjX family protein	NA	NA	NA	NA
WP_001201751.1\|541206_542325_+	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.4e-08	38.9
WP_000125877.1\|542321_544268_+	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	2.0e-39	43.1
WP_000447499.1\|544397_544619_-	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	9.3e-18	64.2
WP_000520789.1\|544942_545263_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	4.5e-13	45.7
WP_001623444.1\|545293_547570_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	6.2e-165	42.3
WP_001623499.1\|547782_547980_-	hypothetical protein	NA	NA	NA	NA
WP_023228156.1\|548141_548519_-\|integrase	integrase	A0A077KET4	Ralstonia_phage	1.2e-20	41.0
WP_000097893.1\|549186_549864_-	hydrolase	NA	NA	NA	NA
WP_000809969.1\|549883_550744_-	pirin family protein	NA	NA	NA	NA
WP_000597928.1\|550852_551764_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_001040187.1\|551854_552073_-	translation initiation factor IF-1	NA	NA	NA	NA
WP_001611348.1\|552000_552384_-	hypothetical protein	NA	NA	NA	NA
WP_001241640.1\|552384_553089_-\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001202249.1\|553133_554855_-	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	W8CYL7	Bacillus_phage	1.9e-12	23.3
WP_001044531.1\|554855_556622_-	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	6.0e-22	25.1
WP_023228155.1\|556736_557705_-	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	6.5e-63	45.5
WP_000228469.1\|558251_558746_+	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_024148295.1\|558880_562870_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	2.8e-88	49.5
WP_001519746.1\|563012_563624_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_000067785.1\|563633_564977_+	replication-associated recombination protein RarA	G3MBE0	Bacillus_virus	1.6e-80	40.9
WP_000886697.1\|565235_566528_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	8.6e-95	44.5
570449:570465	attR	NA	NA	NA	NA

DBSCAN-SWA_2

598849 : 663316

Salmonella_phage(48.0%)

head,tRNA,protease,lysis,terminase,tail,integrase,capsid,holin,portal,transposase

attL 600984:600999|attR 635245:635260

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001154028.1\|598849_599653_+\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA
WP_001288828.1\|599645_600968_+	chromosome partition protein MukF	NA	NA	NA	NA
WP_000060025.1\|600948_601653_+	chromosome partition protein MukE	NA	NA	NA	NA
600984:600999	attL	NA	NA	NA	NA
WP_023228147.1\|601652_606119_+	chromosome partition protein MukB	NA	NA	NA	NA
WP_023228146.1\|606463_608305_+	L,D-transpeptidase	NA	NA	NA	NA
WP_000357052.1\|608564_609113_+	YcbK family protein	A0A0K1LKR7	Rhodobacter_phage	1.2e-05	33.7
WP_001109471.1\|609140_609788_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_000462653.1\|609849_611040_-	aspartate transaminase	NA	NA	NA	NA
WP_000977709.1\|611224_612316_-	porin OmpF	Q1MVN1	Enterobacteria_phage	1.7e-99	51.7
WP_023201779.1\|612921_614322_-\|tRNA	asparagine--tRNA ligase	A0A2K9V902	Bandra_megavirus	5.9e-81	35.8
WP_000762343.1\|614522_614984_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_000544849.1\|615300_616515_+	diaminopropionate ammonia-lyase	NA	NA	NA	NA
WP_023228145.1\|616760_618197_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_000191404.1\|618274_619477_-	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
WP_001262307.1\|619671_620964_-\|integrase	site-specific integrase	S4TSP2	Salmonella_phage	3.4e-253	100.0
WP_000065276.1\|621008_621257_-	excisionase family protein	S4TND0	Salmonella_phage	4.7e-42	100.0
WP_001237031.1\|621297_621537_-	DUF4060 family protein	S4TR31	Salmonella_phage	2.0e-37	100.0
WP_001539618.1\|621579_622737_-	recombinase RecT	S4TTE8	Salmonella_phage	1.6e-217	100.0
WP_023228144.1\|622699_625900_-	gifsy-1 prophage RecE	S4TNL0	Salmonella_phage	0.0e+00	79.4
WP_014344515.1\|626026_626377_-	hypothetical protein	S4TSN6	Salmonella_phage	2.7e-59	94.0
WP_000917561.1\|626398_626557_-	hypothetical protein	H6WRX3	Salmonella_phage	2.6e-22	96.2
WP_001009038.1\|626955_627360_-	transcriptional regulator	H6WRX4	Salmonella_phage	4.2e-72	100.0
WP_000869364.1\|627489_627726_+	Cro/Cl family transcriptional regulator	H6WRX5	Salmonella_phage	1.8e-38	100.0
WP_001574095.1\|627691_628066_+	hypothetical protein	S4TTD7	Salmonella_phage	3.9e-64	99.2
WP_001191964.1\|628339_629401_+	DUF1376 domain-containing protein	A0A0U2RT81	Escherichia_phage	3.3e-36	83.0
WP_000800012.1\|629403_630153_+	ATP-binding protein	S4TNF5	Salmonella_phage	4.3e-139	100.0
WP_000113621.1\|630163_630511_+	DUF977 family protein	H6WRX9	Salmonella_phage	1.5e-57	98.3
WP_000065341.1\|630507_630909_+	ParB/RepB/Spo0J family partition protein	S4TTI6	Salmonella_phage	2.9e-73	100.0
WP_000151011.1\|630905_631358_+	ead/Ea22-like family protein	S4TNP2	Salmonella_phage	3.8e-74	100.0
WP_000208070.1\|631354_632164_+	DUF550 domain-containing protein	S4TSR6	Salmonella_phage	4.5e-158	100.0
WP_001217670.1\|632683_632923_+	DinI family protein	H6WRY5	Salmonella_phage	3.9e-38	100.0
WP_023228142.1\|633256_633859_+	DUF1367 family protein	S4TTI0	Salmonella_phage	1.7e-109	99.0
WP_001096553.1\|634067_634679_+	recombination protein NinG	A0A0M4RU10	Salmonella_phage	2.7e-91	98.5
WP_000801757.1\|634675_634816_+	YlcG family protein	A0A0M5M7B2	Salmonella_phage	7.2e-08	78.9
WP_001097240.1\|634812_635502_+	antitermination protein	I6PDF8	Cronobacter_phage	1.1e-59	52.4
635245:635260	attR	NA	NA	NA	NA
WP_000657897.1\|635991_636180_+	hypothetical protein	NA	NA	NA	NA
WP_001110787.1\|636394_637081_-\|protease	type III secretion system effector protease GogA	Q9MBM2	Phage_Gifsy-1	3.6e-132	99.6
WP_001574216.1\|637356_637686_+\|holin	phage holin, lambda family	A0A0M3ULK9	Salmonella_phage	5.8e-56	100.0
WP_000984583.1\|637669_638122_+	lysozyme	A0A0M4R365	Salmonella_phage	4.6e-80	98.7
WP_031606933.1\|638139_638586_+\|lysis	lysis protein	A0A0M4RD57	Salmonella_phage	1.1e-62	88.4
WP_000669689.1\|638812_639214_-	hypothetical protein	NA	NA	NA	NA
WP_001102152.1\|639499_640045_+\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	1.9e-56	79.9
WP_076018218.1\|640016_641948_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	4.8e-259	65.7
WP_000201415.1\|641931_642135_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	1.9e-17	73.8
WP_001623362.1\|642131_643712_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	2.8e-188	62.6
WP_023226259.1\|643701_645198_+	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	4.3e-98	52.7
WP_000011260.1\|645210_645558_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	9.2e-20	52.7
WP_001623560.1\|645612_646641_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.3e-114	61.1
WP_000201485.1\|646698_647064_+	DNA packaging protein	NA	NA	NA	NA
WP_000083292.1\|647074_647458_+\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	1.2e-28	55.6
WP_000817265.1\|647490_648621_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q9G0F2	Phage_Gifsy-1	4.0e-213	98.1
WP_000677089.1\|648729_649308_+\|tail	phage tail protein	A5LH33	Enterobacteria_phage	3.7e-82	80.2
WP_000033885.1\|649304_649706_+\|tail	tail protein	Q9G0F3	Phage_Gifsy-1	8.1e-52	100.0
WP_000971954.1\|649713_650460_+\|tail	tail protein	A0A291AWU6	Escherichia_phage	1.9e-99	76.9
WP_000479607.1\|650510_650906_+\|tail	phage minor tail protein G	A5LH36	Enterobacteria_phage	2.3e-30	56.5
WP_010989052.1\|650902_651241_+\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	1.3e-31	62.4
WP_001623563.1\|651212_654308_+\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	1.4e-276	61.6
WP_000447370.1\|654310_654640_+\|tail	phage tail protein	A5LH39	Enterobacteria_phage	7.3e-43	71.3
WP_001156291.1\|654649_655348_+\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	4.6e-103	75.4
WP_000662736.1\|655354_656092_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	4.0e-129	85.0
WP_000246124.1\|655989_656637_+\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	9.3e-90	78.1
WP_076018219.1\|656698_660103_+	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	75.3
WP_023228166.1\|660146_662777_+\|tail	side tail fiber protein	A0A1B0VFW4	Salmonella_phage	1.8e-152	64.2
WP_108426318.1\|662854_663316_+\|tail	tail fiber assembly protein	A0A1S6KZZ1	Salmonella_phage	4.2e-68	84.7

DBSCAN-SWA_3

737443 : 746614

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569166.1\|737443_738391_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-23	31.2
WP_000824854.1\|738374_739106_+	ABC transporter permease	NA	NA	NA	NA
WP_001261696.1\|739086_739194_-	protein YohO	NA	NA	NA	NA
WP_001240417.1\|739253_739985_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	4.5e-101	87.9
WP_000272850.1\|740207_741893_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	4.8e-279	91.3
WP_000598637.1\|741889_742609_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001624991.1\|742655_743123_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	8.8e-74	89.7
WP_001197951.1\|743179_743710_-	YehR family lipoprotein	NA	NA	NA	NA
WP_001624990.1\|743881_744340_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.6e-51	71.9
WP_023228437.1\|744580_746614_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	6.1e-55	26.9

DBSCAN-SWA_4

924765 : 975919

Salmonella_phage(70.0%)

head,terminase,protease,tail,integrase,plate,capsid,holin,portal

attL 917729:917744|attR 954982:954997

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
917729:917744	attL	NA	NA	NA	NA
WP_023228394.1\|924765_926034_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.8e-76	40.4
WP_001736108.1\|926697_926988_-	DUF4102 domain-containing protein	B7SYF8	Stenotrophomonas_phage	3.0e-08	49.1
WP_000598920.1\|927359_928157_-	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_000532847.1\|928448_929438_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	8.6e-196	100.0
WP_000414876.1\|929439_929682_-	DUF4224 domain-containing protein	Q8HAA9	Salmonella_phage	9.5e-40	100.0
WP_023228393.1\|929706_930276_-	3'-5' exoribonuclease	A0A192Y6E0	Salmonella_phage	1.2e-109	99.5
WP_024148319.1\|930279_930981_-	hypothetical protein	Q8HAA7	Salmonella_phage	3.6e-79	59.9
WP_020898896.1\|930985_931345_-	hypothetical protein	A0A1L7N114	Ralstonia_phage	2.1e-22	49.1
WP_023228391.1\|931344_931884_-	hypothetical protein	A0A192Y7N1	Salmonella_phage	1.5e-64	71.3
WP_000008351.1\|931954_932494_-	hypothetical protein	A0A192Y8M4	Salmonella_phage	2.6e-98	100.0
WP_053299710.1\|932630_933458_-	YfdQ family protein	Q8HAA2	Salmonella_phage	7.1e-151	98.5
WP_000997190.1\|933515_933887_-	hypothetical protein	Q8HAA1	Salmonella_phage	1.1e-63	100.0
WP_000141749.1\|934183_934414_+	hypothetical protein	NA	NA	NA	NA
WP_023228487.1\|934872_935079_+	hypothetical protein	K7P7I0	Enterobacteria_phage	7.1e-20	71.6
WP_023228488.1\|935098_935311_-	hypothetical protein	NA	NA	NA	NA
WP_024148333.1\|935378_935726_-	hypothetical protein	NA	NA	NA	NA
WP_031622327.1\|935742_936447_-	hypothetical protein	G8C7U1	Escherichia_phage	1.2e-66	59.0
WP_024148334.1\|936553_936817_+	hypothetical protein	H6WRX5	Salmonella_phage	3.2e-09	48.4
WP_000509733.1\|936845_937400_+	hypothetical protein	A0A1C9II13	Salmonella_phage	2.0e-101	99.5
WP_076018222.1\|937396_938554_+	peptidase	Q8HA97	Salmonella_phage	4.8e-214	97.9
WP_000620702.1\|938550_938775_+	hypothetical protein	A0A1C9II64	Salmonella_phage	3.3e-39	100.0
WP_070810380.1\|938771_939731_+	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	1.6e-117	80.9
WP_023171062.1\|939732_940215_+	PerC family transcriptional regulator	Q8HA95	Salmonella_phage	1.6e-86	98.8
WP_001624543.1\|940214_940868_+	phage N-6-adenine-methyltransferase	Q8SBE9	Shigella_phage	7.1e-114	88.0
WP_023228498.1\|940864_941254_+	RusA family crossover junction endodeoxyribonuclease	K7PH72	Enterobacteria_phage	2.1e-60	86.0
WP_023228497.1\|941270_942131_+	KilA-N domain-containing protein	A0A192Y6F8	Salmonella_phage	4.3e-159	97.9
WP_070804833.1\|942138_943128_+	DUF968 domain-containing protein	A0A1C9IHZ5	Salmonella_phage	2.6e-192	98.8
WP_023227964.1\|943141_943894_+	antitermination protein	Q8SBE4	Shigella_phage	3.5e-133	97.2
WP_001306866.1\|944183_944426_+	hypothetical protein	NA	NA	NA	NA
WP_162493699.1\|944563_944899_+\|holin	phage holin, lambda family	Q8SBE1	Shigella_phage	2.1e-53	92.8
WP_023227966.1\|944902_945373_+	glycoside hydrolase family protein	S5FV07	Shigella_phage	7.7e-86	97.4
WP_024148265.1\|945362_945755_+	DUF2570 domain-containing protein	U5P0U9	Shigella_phage	1.3e-51	84.6
WP_023227967.1\|946285_946480_+	hypothetical protein	NA	NA	NA	NA
WP_023227968.1\|946532_946883_+	HNH endonuclease	M1FQV2	Enterobacteria_phage	8.9e-63	95.7
WP_000929191.1\|947006_947501_+\|terminase	phage terminase small subunit P27 family	Q8HAD7	Salmonella_phage	4.6e-89	100.0
WP_000088185.1\|947497_949231_+\|terminase	terminase large subunit	Q8HAD6	Salmonella_phage	0.0e+00	99.8
WP_000605609.1\|949242_949425_+	hypothetical protein	Q8HAD5	Salmonella_phage	1.0e-25	100.0
WP_023227969.1\|949424_950666_+\|portal	phage portal protein	Q8HAD4	Salmonella_phage	8.5e-241	99.3
WP_001193639.1\|950643_951294_+\|head,protease	HK97 family phage prohead protease	Q8HAD3	Salmonella_phage	1.5e-119	100.0
WP_000257528.1\|951308_952514_+\|capsid	phage major capsid protein	Q8HAD2	Salmonella_phage	1.6e-223	100.0
WP_000601353.1\|952564_952765_+	hypothetical protein	Q8HAD1	Salmonella_phage	1.4e-28	100.0
WP_000927378.1\|952767_953091_+\|head,tail	phage gp6-like head-tail connector protein	A0A192Y8J4	Salmonella_phage	6.3e-55	100.0
WP_000702409.1\|953087_953492_+\|head	phage head closure protein	A0A192Y6C2	Salmonella_phage	5.4e-72	99.3
WP_001135697.1\|953463_953976_+	hypothetical protein	Q8HAC8	Salmonella_phage	4.6e-92	100.0
WP_000779215.1\|953972_954533_+	hypothetical protein	A0A192Y5U4	Salmonella_phage	3.0e-105	99.5
WP_000497739.1\|954536_954701_+	DUF2635 domain-containing protein	Q8HAC6	Salmonella_phage	1.0e-24	100.0
WP_023227970.1\|954690_956187_+\|tail	bacteriophage Mu tail sheath protein	A0A192Y7L1	Salmonella_phage	8.0e-278	99.8
954982:954997	attR	NA	NA	NA	NA
WP_000515952.1\|956186_956543_+\|tail	tail protein	A0A192Y8K0	Salmonella_phage	2.6e-62	100.0
WP_000588852.1\|956539_956866_+\|tail	phage tail assembly protein	Q8HAC3	Salmonella_phage	2.3e-52	99.1
WP_023227971.1\|956950_958879_+\|tail	phage tail tape measure protein	Q8HAC2	Salmonella_phage	0.0e+00	99.2
WP_023227972.1\|958912_960253_+\|tail	tail/DNA circulation protein	A0A192Y5U9	Salmonella_phage	2.0e-248	98.7
WP_001624460.1\|960249_961308_+\|tail	phage tail protein	A0A192Y7L7	Salmonella_phage	6.6e-202	99.4
WP_001273647.1\|961307_961841_+\|plate	phage baseplate assembly protein	Q8HAB9	Salmonella_phage	1.9e-96	99.4
WP_023227973.1\|961845_962259_+	phage protein	Q8HAB8	Salmonella_phage	1.2e-71	94.2
WP_000785580.1\|962251_963331_+\|plate	baseplate J/gp47 family protein	A0A192Y6E4	Salmonella_phage	2.5e-204	99.7
WP_001207832.1\|963333_963921_+	DUF2313 domain-containing protein	A0A192Y5V3	Salmonella_phage	2.9e-114	100.0
WP_000554737.1\|963907_965470_+	hypothetical protein	Q8HAB4	Salmonella_phage	2.6e-287	100.0
WP_015701331.1\|965439_966039_+\|tail	tail fiber assembly protein	Q8HAB3	Salmonella_phage	5.9e-107	100.0
WP_000492926.1\|966323_967331_-	type III secretion system effector arginine glycosyltransferase	Q8HAB2	Salmonella_phage	7.9e-197	100.0
WP_023227974.1\|967543_967765_+	helix-turn-helix domain-containing protein	Q8HAB1	Salmonella_phage	9.9e-36	98.6
WP_001529333.1\|968395_968557_+	hypothetical protein	NA	NA	NA	NA
WP_000394197.1\|968683_969103_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.5e-36	60.5
WP_023227975.1\|969105_970374_+	Y-family DNA polymerase	I6RSM4	Salmonella_phage	4.6e-226	92.2
WP_000208509.1\|970828_971041_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	3.9e-21	70.0
WP_024131109.1\|971051_971240_+	hypothetical protein	NA	NA	NA	NA
WP_001080668.1\|971500_972679_-	porin OmpS1	Q1MVN1	Enterobacteria_phage	6.6e-110	57.2
WP_000107437.1\|973328_973640_+	hypothetical protein	NA	NA	NA	NA
WP_000377042.1\|973719_974415_+	phosphohydrolase	A0A1D6Y7U0	Golden_Marseillevirus	2.8e-07	27.1
WP_001623639.1\|974488_975919_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	1.0e-104	57.4

DBSCAN-SWA_5

1079124 : 1088354

Salmonella_phage(28.57%)

integrase,tail

attL 1073568:1073582|attR 1084466:1084480

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1073568:1073582	attL	NA	NA	NA	NA
WP_000856224.1\|1079124_1079355_-	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	2.9e-14	60.3
WP_000168393.1\|1079492_1079867_+	CopC domain-containing protein YobA	NA	NA	NA	NA
WP_001623761.1\|1079867_1080743_+	copper homeostasis membrane protein CopD	NA	NA	NA	NA
WP_023227990.1\|1080759_1081113_+	YebY family protein	NA	NA	NA	NA
WP_001623770.1\|1081495_1082575_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	8.7e-101	52.5
WP_023227991.1\|1082571_1083678_-	hypothetical protein	Q9QF34	Lambdoid_phage	1.5e-55	66.1
WP_001013467.1\|1083708_1083939_+	hypothetical protein	Q8HA86	Salmonella_phage	6.1e-28	93.7
WP_001050883.1\|1083992_1084526_+	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	5.4e-11	43.0
1084466:1084480	attR	NA	NA	NA	NA
WP_000789530.1\|1084782_1084950_-	lytic enzyme	NA	NA	NA	NA
WP_001532317.1\|1085014_1085203_-	hypothetical protein	NA	NA	NA	NA
WP_001623776.1\|1085257_1085749_+	DUF1441 family protein	Q9EYD0	Enterobacteria_phage	1.1e-39	55.0
WP_015675561.1\|1087853_1088354_+\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	8.8e-64	78.0

DBSCAN-SWA_6

1874664 : 1921184

Escherichia_phage(32.5%)

integrase,protease,terminase,tail

attL 1894974:1894987|attR 1921849:1921862

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077905582.1\|1874664_1874988_-	hypothetical protein	E5G6P3	Salmonella_phage	3.2e-06	68.1
WP_001623600.1\|1875202_1876078_+	SPI-2 type III secretion system effector PipB	NA	NA	NA	NA
WP_024148298.1\|1876299_1876953_+\|protease	type III secretion system effector protease PipA	Q9MBM0	Phage_Gifsy-2	3.8e-75	68.7
WP_023228192.1\|1877342_1877609_+	hypothetical protein	A0A0M3ULK3	Salmonella_phage	3.7e-37	86.4
WP_023228193.1\|1877624_1877816_-	DUF2767 family protein	A0A0M4R5C3	Salmonella_phage	5.8e-16	97.7
WP_024148299.1\|1877925_1878360_-	hypothetical protein	NA	NA	NA	NA
WP_023228195.1\|1878715_1879315_-\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	6.8e-87	82.9
WP_024148300.1\|1879304_1879541_-	hypothetical protein	A0A0M4QWS3	Salmonella_phage	2.8e-20	50.0
WP_065304957.1\|1879668_1879860_-	hypothetical protein	A0A0M4QWS3	Salmonella_phage	7.5e-24	92.1
WP_023228196.1\|1879856_1881566_-\|tail	tail fiber protein	A0A0U2SAV1	Escherichia_phage	7.6e-91	65.6
WP_023136425.1\|1881562_1882189_-	hypothetical protein	A0A0U2RK03	Escherichia_phage	1.3e-91	71.2
WP_023228197.1\|1882172_1883399_-	hypothetical protein	A0A0U2RJZ0	Escherichia_phage	2.1e-151	65.4
WP_023228198.1\|1883395_1883728_-	hypothetical protein	NA	NA	NA	NA
WP_023228199.1\|1883724_1884441_-	hypothetical protein	NA	NA	NA	NA
WP_001213276.1\|1884437_1885481_-	hypothetical protein	NA	NA	NA	NA
WP_000116517.1\|1885480_1885756_-	hypothetical protein	NA	NA	NA	NA
WP_000011139.1\|1885752_1886469_-	hypothetical protein	A0A0U2JGI7	Escherichia_phage	1.0e-28	36.5
WP_023228200.1\|1886468_1888523_-	hypothetical protein	A0A2R3UAN6	Myoviridae_environmental_samples	1.7e-20	35.8
WP_000268744.1\|1888646_1889234_-	hypothetical protein	NA	NA	NA	NA
WP_001133547.1\|1889233_1889671_-	hypothetical protein	NA	NA	NA	NA
WP_001018951.1\|1889674_1891069_-	hypothetical protein	A0A0U2KD19	Escherichia_phage	6.0e-70	36.8
WP_001139605.1\|1891074_1892013_-	hypothetical protein	A0A0U2SH76	Escherichia_phage	2.5e-51	39.5
WP_031604700.1\|1891996_1892407_-	hypothetical protein	NA	NA	NA	NA
WP_001114360.1\|1892424_1892850_-	hypothetical protein	NA	NA	NA	NA
WP_001643824.1\|1892862_1893348_-	hypothetical protein	NA	NA	NA	NA
WP_001110972.1\|1893412_1894444_-	DUF2184 domain-containing protein	A0A0U2QQI2	Escherichia_phage	1.5e-73	45.5
WP_001262267.1\|1894461_1895334_-	hypothetical protein	NA	NA	NA	NA
1894974:1894987	attL	NA	NA	NA	NA
WP_000860554.1\|1895354_1896929_-	NUDIX domain-containing protein	Q6UJ14	Burkholderia_virus	1.7e-20	48.6
WP_023228201.1\|1896929_1897805_-	hypothetical protein	A0A0U2I1R8	Escherichia_phage	1.1e-56	45.8
WP_023228202.1\|1897776_1899207_-	DUF1073 domain-containing protein	A0A0U2S5X9	Escherichia_phage	9.8e-92	37.7
WP_000179871.1\|1899206_1900478_-	hypothetical protein	A0A0U2JTW9	Escherichia_phage	6.1e-85	38.8
WP_023228203.1\|1900467_1901439_-\|terminase	terminase small subunit	I6NV32	Burkholderia_virus	5.0e-23	32.8
WP_001288297.1\|1901503_1901917_-	hypothetical protein	NA	NA	NA	NA
WP_108426293.1\|1901977_1902514_-	DUF2514 family protein	A0A193GYI0	Enterobacter_phage	1.4e-11	32.0
WP_023228205.1\|1902495_1903035_-	lysozyme	H6WRZ4	Salmonella_phage	4.4e-101	98.9
WP_023228207.1\|1903851_1904430_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	1.7e-42	50.3
WP_023228208.1\|1904426_1904720_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	1.4e-32	64.2
WP_023228209.1\|1904716_1905313_-	DUF1367 family protein	H9C173	Pectobacterium_phage	3.2e-81	72.7
WP_000474096.1\|1905381_1905573_-	hypothetical protein	NA	NA	NA	NA
WP_001129735.1\|1905756_1906095_-	hypothetical protein	A0A193GYX4	Enterobacter_phage	3.7e-50	86.6
WP_023228210.1\|1906094_1908068_-	hypothetical protein	H9C171	Pectobacterium_phage	3.1e-205	54.2
WP_023228211.1\|1908064_1908820_-	class I SAM-dependent methyltransferase	H9C170	Pectobacterium_phage	9.9e-67	78.1
WP_023228212.1\|1908816_1909419_-	adenine methylase	G9L699	Escherichia_phage	2.3e-98	87.3
WP_000918618.1\|1909411_1909660_-	hypothetical protein	NA	NA	NA	NA
WP_023228213.1\|1909663_1910344_-	hypothetical protein	NA	NA	NA	NA
WP_031609362.1\|1910382_1911777_-	replicative DNA helicase	Q76H51	Enterobacteria_phage	5.2e-106	47.4
WP_023228215.1\|1911785_1912766_-	helix-turn-helix domain-containing protein	H9C164	Pectobacterium_phage	5.2e-44	79.6
WP_023228216.1\|1912768_1912993_-	hypothetical protein	H9C163	Pectobacterium_phage	8.0e-09	44.7
WP_024138915.1\|1913015_1913462_-	hypothetical protein	H9C162	Pectobacterium_phage	9.4e-25	50.4
WP_023228218.1\|1913526_1913730_-	transcriptional regulator	K7PHK4	Enterobacteria_phage	4.0e-07	46.6
WP_024142132.1\|1913808_1914210_+	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	2.5e-37	55.6
WP_010835722.1\|1914864_1915188_+	hypothetical protein	NA	NA	NA	NA
WP_023228220.1\|1915195_1915441_+	hypothetical protein	A0A1B1W282	Salmonella_phage	3.5e-13	53.8
WP_023228221.1\|1915470_1917744_+	hypothetical protein	H9C157	Pectobacterium_phage	1.1e-108	35.3
WP_023228222.1\|1917740_1918295_+	siphovirus Gp157 family protein	H9C156	Pectobacterium_phage	1.7e-47	59.3
WP_000916251.1\|1918297_1918480_+	hypothetical protein	NA	NA	NA	NA
WP_000196402.1\|1918692_1918917_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_023228223.1\|1918917_1919937_+\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	1.6e-91	53.2
WP_000374046.1\|1920524_1921184_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	2.7e-44	52.4
1921849:1921862	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1935195 : 2024849

100

Salmonella_phage(33.33%)

head,protease,tail,terminase,capsid,holin,portal,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001623584.1\|1935195_1936956_+\|protease	Lon protease family protein	NA	NA	NA	NA
WP_000227928.1\|1937024_1937543_+	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_001537784.1\|1937642_1937810_-	ribosome modulation factor	NA	NA	NA	NA
WP_000759136.1\|1938065_1938629_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_000433416.1\|1938625_1940266_-	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_000333152.1\|1940270_1941524_-	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_000053044.1\|1941538_1943446_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	2.4e-53	29.8
WP_001086485.1\|1943458_1945567_-	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_001623556.1\|1945665_1946775_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_001220671.1\|1946771_1947314_-	cell division protein ZapC	NA	NA	NA	NA
WP_000291723.1\|1947479_1948490_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_001623553.1\|1948697_1951310_-	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	6.3e-20	22.6
WP_000497441.1\|1951736_1951928_+	DinI-like family protein	S4TNM0	Salmonella_phage	6.2e-26	95.2
WP_001525490.1\|1952198_1952885_+	hypothetical protein	NA	NA	NA	NA
WP_077911262.1\|1952963_1953083_-\|tail	phage tail protein	A0A0M4RTP2	Salmonella_phage	7.5e-06	68.8
WP_000480002.1\|1953792_1954494_+	T3SS effector NleG family protein	B6DZC0	Enterobacteria_phage	1.3e-15	29.2
WP_001093795.1\|1955724_1955937_+	hypothetical protein	A0A192Y5V6	Salmonella_phage	1.6e-27	92.9
WP_000842530.1\|1955933_1956335_+	hypothetical protein	A0A192Y6F0	Salmonella_phage	4.7e-60	89.7
WP_125468752.1\|1956395_1956509_+	hypothetical protein	A0A1C9IHU6	Salmonella_phage	1.8e-09	91.9
WP_000836775.1\|1956582_1956816_+	hypothetical protein	A0A192Y6D5	Salmonella_phage	1.8e-35	97.4
WP_023219780.1\|1957090_1957732_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_023228228.1\|1957902_1958421_-\|tail	tail fiber assembly protein	A0A0U2QV64	Escherichia_phage	2.3e-46	53.2
WP_023228229.1\|1958435_1961117_-\|tail	side tail fiber protein	A0A1B0VFW4	Salmonella_phage	2.4e-147	64.2
WP_000178853.1\|1961172_1961415_-	hypothetical protein	NA	NA	NA	NA
WP_070811210.1\|1961453_1964816_-	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	79.7
WP_000246124.1\|1964877_1965525_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	9.3e-90	78.1
WP_000662736.1\|1965422_1966160_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	4.0e-129	85.0
WP_001156291.1\|1966166_1966865_-\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	4.6e-103	75.4
WP_000447370.1\|1966874_1967204_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	7.3e-43	71.3
WP_001623563.1\|1967206_1970302_-\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	1.4e-276	61.6
WP_010989052.1\|1970273_1970612_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	1.3e-31	62.4
WP_000479607.1\|1970608_1971004_-\|tail	phage minor tail protein G	A5LH36	Enterobacteria_phage	2.3e-30	56.5
WP_000971954.1\|1971054_1971801_-\|tail	tail protein	A0A291AWU6	Escherichia_phage	1.9e-99	76.9
WP_000033885.1\|1971808_1972210_-\|tail	tail protein	Q9G0F3	Phage_Gifsy-1	8.1e-52	100.0
WP_000677089.1\|1972206_1972785_-\|tail	phage tail protein	A5LH33	Enterobacteria_phage	3.7e-82	80.2
WP_000817265.1\|1972893_1974024_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q9G0F2	Phage_Gifsy-1	4.0e-213	98.1
WP_000083292.1\|1974056_1974440_-\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	1.2e-28	55.6
WP_000201485.1\|1974450_1974816_-	DNA packaging protein	NA	NA	NA	NA
WP_001623560.1\|1974873_1975902_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.3e-114	61.1
WP_000011260.1\|1975956_1976304_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	9.2e-20	52.7
WP_023226259.1\|1976316_1977813_-	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	4.3e-98	52.7
WP_001623362.1\|1977802_1979383_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	2.8e-188	62.6
WP_000201415.1\|1979379_1979583_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	1.9e-17	73.8
WP_023187571.1\|1979566_1981498_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	1.7e-259	65.9
WP_070793402.1\|1981469_1982015_-\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	7.4e-56	79.1
WP_023227962.1\|1982059_1982251_-	hypothetical protein	NA	NA	NA	NA
WP_031622290.1\|1982273_1982777_-	hypothetical protein	NA	NA	NA	NA
WP_023227960.1\|1982879_1983422_-	DUF2514 family protein	NA	NA	NA	NA
WP_023227959.1\|1983418_1984033_-	glycoside hydrolase family 19 protein	Q8HA86	Salmonella_phage	2.3e-106	91.7
WP_001623358.1\|1984035_1984377_-\|holin	phage holin, lambda family	Q8SBE1	Shigella_phage	4.3e-46	81.3
WP_001624514.1\|1985986_1986175_-	hypothetical protein	NA	NA	NA	NA
WP_024148263.1\|1986677_1987511_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_023227958.1\|1987803_1988607_-	antitermination protein	F1C595	Cronobacter_phage	4.8e-104	71.5
WP_001624522.1\|1988603_1988876_-	hypothetical protein	A0A1B5FPA6	Escherichia_phage	1.7e-29	82.9
WP_070804833.1\|1988890_1989880_-	DUF968 domain-containing protein	A0A1C9IHZ5	Salmonella_phage	2.6e-192	98.8
WP_023227955.1\|1989887_1990688_-	KilA-N domain-containing protein	A0A0P0ZCS0	Stx2-converting_phage	8.7e-106	72.2
WP_001529171.1\|1990704_1991094_-	RusA family crossover junction endodeoxyribonuclease	K7PH72	Enterobacteria_phage	9.2e-61	86.8
WP_023227954.1\|1991090_1991744_-	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	1.3e-112	87.6
WP_023227953.1\|1991743_1992226_-	PerC family transcriptional regulator	Q8HA95	Salmonella_phage	2.5e-84	96.9
WP_076018227.1\|1992227_1993172_-	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	1.3e-129	85.7
WP_000620702.1\|1993168_1993393_-	hypothetical protein	A0A1C9II64	Salmonella_phage	3.3e-39	100.0
WP_023228495.1\|1993389_1994229_-	putative antirepressor from phage	A0A1C9IHV9	Salmonella_phage	8.2e-147	97.8
WP_024131287.1\|1994253_1994583_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	2.6e-40	90.8
WP_000147078.1\|1994572_1994881_+	helix-turn-helix transcriptional regulator	A0A088CD40	Shigella_phage	2.5e-45	93.1
WP_001525520.1\|1994899_1995076_-	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	4.6e-28	94.6
WP_070811212.1\|1995215_1995770_-	hypothetical protein	A0A1C9II13	Salmonella_phage	7.6e-101	98.4
WP_001191666.1\|1995798_1996023_-	helix-turn-helix transcriptional regulator	A0A1C9IHV8	Salmonella_phage	1.9e-34	100.0
WP_001020640.1\|1996120_1996816_+	helix-turn-helix transcriptional regulator	Q8HAA0	Salmonella_phage	4.6e-127	99.6
WP_001624554.1\|1997150_1997348_-	hypothetical protein	NA	NA	NA	NA
WP_000997190.1\|1997886_1998258_+	hypothetical protein	Q8HAA1	Salmonella_phage	1.1e-63	100.0
WP_070811010.1\|1998315_1999143_+	YfdQ family protein	A0A192Y6E5	Salmonella_phage	1.1e-151	98.9
WP_000008351.1\|1999279_1999819_+	hypothetical protein	A0A192Y8M4	Salmonella_phage	2.6e-98	100.0
WP_024148247.1\|2000527_2000815_+	hypothetical protein	A5VWB2	Enterobacteria_phage	3.2e-26	58.8
WP_023227853.1\|2000818_2001244_+	HNH endonuclease	C6ZR29	Salmonella_phage	6.8e-65	83.8
WP_023227852.1\|2001240_2001678_+	hypothetical protein	Q5G8V2	Enterobacteria_phage	1.8e-44	56.9
WP_023227851.1\|2001804_2002014_+	hypothetical protein	NA	NA	NA	NA
WP_001623414.1\|2002016_2003195_+	hypothetical protein	A0A2D1GN00	Marinobacter_phage	1.8e-30	30.1
WP_001623413.1\|2003315_2004374_+	hypothetical protein	A0A2I7RNF6	Vibrio_phage	4.6e-62	42.1
WP_076018228.1\|2007783_2008146_-\|tail	phage tail protein	S4TUB9	Salmonella_phage	2.5e-52	86.5
WP_024131629.1\|2008229_2009021_-\|tail	tail protein	Q1MVL8	Enterobacteria_phage	9.7e-49	31.6
WP_023227850.1\|2009149_2009338_+	hypothetical protein	NA	NA	NA	NA
WP_001142121.1\|2009324_2009513_+	hypothetical protein	NA	NA	NA	NA
WP_000281877.1\|2009704_2010268_-	acyloxyacyl hydrolase	NA	NA	NA	NA
WP_001115497.1\|2010997_2011645_+	nitrate/nitrite response regulator protein NarP	NA	NA	NA	NA
WP_001238328.1\|2011688_2012732_-	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_000828299.1\|2012728_2013286_-	thiol:disulfide interchange protein DsbE	NA	NA	NA	NA
WP_001625168.1\|2013282_2015214_-	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_001053607.1\|2015210_2015690_-	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_000074110.1\|2015686_2015899_-	heme exporter protein CcmD	NA	NA	NA	NA
WP_023228369.1\|2015895_2016633_-	heme ABC transporter permease	NA	NA	NA	NA
WP_000990033.1\|2016684_2017344_-	heme exporter protein CcmB	NA	NA	NA	NA
WP_076018229.1\|2017340_2017958_-	cytochrome c biogenesis heme-transporting ATPase CcmA	A0A2H4PQG7	Staphylococcus_phage	8.2e-11	26.9
WP_023228100.1\|2017978_2018581_-	cytochrome c-type protein NapC	NA	NA	NA	NA
WP_000835182.1\|2018590_2019040_-	nitrate reductase cytochrome c-type subunit	NA	NA	NA	NA
WP_001625189.1\|2019155_2020025_-	quinol dehydrogenase ferredoxin subunit NapH	NA	NA	NA	NA
WP_000091679.1\|2020011_2020707_-	ferredoxin-type protein NapG	NA	NA	NA	NA
WP_000778097.1\|2020713_2023200_-	nitrate reductase catalytic subunit NapA	NA	NA	NA	NA
WP_001260058.1\|2023196_2023460_-	chaperone NapD	NA	NA	NA	NA
WP_023228101.1\|2023449_2023941_-	ferredoxin-type protein NapF	NA	NA	NA	NA
WP_000781589.1\|2024354_2024849_+\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA

DBSCAN-SWA_8

3049663 : 3143462

104

Vibrio_phage(28.0%)

tRNA,protease,tail,terminase,integrase,plate,capsid,holin,portal

attL 3073897:3073918|attR 3146654:3146675

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000366112.1\|3049663_3050164_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	2.5e-26	55.8
WP_000257298.1\|3050169_3050808_-	stringent starvation protein A	NA	NA	NA	NA
WP_000950539.1\|3051070_3051823_-	DUF695 domain-containing protein	NA	NA	NA	NA
WP_000829815.1\|3052022_3052415_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_000847559.1\|3052430_3052859_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_001191222.1\|3053160_3054285_-	cell division protein ZapE	NA	NA	NA	NA
WP_001519074.1\|3054477_3054876_+	DUF1043 family protein	NA	NA	NA	NA
WP_000716690.1\|3055032_3056400_+\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	2.7e-22	26.3
WP_023228163.1\|3056492_3057563_+	outer membrane-stress sensor serine endopeptidase DegS	NA	NA	NA	NA
WP_023228162.1\|3057596_3058328_-	hypothetical protein	NA	NA	NA	NA
WP_070801135.1\|3058347_3059649_-	oxalacetate decarboxylase subunit beta	NA	NA	NA	NA
WP_070801136.1\|3059661_3061437_-	sodium-extruding oxaloacetate decarboxylase subunit alpha	NA	NA	NA	NA
WP_000180119.1\|3061453_3061696_-	oxaloacetate decarboxylase subunit gamma	NA	NA	NA	NA
WP_000162405.1\|3061852_3062470_-	L(+)-tartrate dehydratase subunit beta	NA	NA	NA	NA
WP_000045349.1\|3062469_3063369_-	L(+)-tartrate dehydratase subunit alpha	NA	NA	NA	NA
WP_000433390.1\|3063401_3064670_-	SLC13/DASS family transporter	Q6A201	Oenococcus_phage	1.1e-59	33.0
WP_023227848.1\|3064880_3065546_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000723776.1\|3065532_3066162_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000861586.1\|3066281_3067220_-	malate dehydrogenase	NA	NA	NA	NA
WP_001257852.1\|3067633_3068104_+	transcriptional regulator ArgR	NA	NA	NA	NA
WP_000695695.1\|3068468_3068732_+	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_000853277.1\|3068835_3069102_+	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_001103887.1\|3069161_3069434_-	hypothetical protein	NA	NA	NA	NA
WP_000510913.1\|3069605_3071573_-	p-hydroxybenzoic acid efflux pump subunit AaeB	NA	NA	NA	NA
WP_000855134.1\|3071578_3072511_-	p-hydroxybenzoic acid efflux pump subunit AaeA	NA	NA	NA	NA
WP_000051840.1\|3072518_3072722_-	AaeX family protein	NA	NA	NA	NA
WP_000440300.1\|3072903_3073833_+	HTH-type transcriptional activator AaeR	NA	NA	NA	NA
3073897:3073918	attL	NA	NA	NA	NA
WP_000055940.1\|3073955_3075401_-\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_001253500.1\|3075545_3079346_-	AsmA2 domain-containing protein	NA	NA	NA	NA
WP_000123188.1\|3079452_3080922_-	ribonuclease G	NA	NA	NA	NA
WP_000210303.1\|3080911_3081505_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_000179403.1\|3081513_3082002_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_000802538.1\|3082004_3083057_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_000913396.1\|3083121_3084165_-	rod shape-determining protein MreB	F2Y0P3	Organic_Lake_phycodnavirus	6.7e-05	22.3
WP_001241381.1\|3084472_3086413_-	RNase E specificity factor CsrD	NA	NA	NA	NA
WP_001148246.1\|3086616_3087591_+	oxidoreductase	NA	NA	NA	NA
WP_000723872.1\|3087703_3088708_+	protein-methionine-sulfoxide reductase catalytic subunit MsrP	NA	NA	NA	NA
WP_001240053.1\|3088708_3089308_+	protein-methionine-sulfoxide reductase heme-binding subunit MsrQ	NA	NA	NA	NA
WP_000354626.1\|3089700_3090171_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_000884627.1\|3090181_3091531_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_000340018.1\|3091639_3091882_+	YhdT family protein	NA	NA	NA	NA
WP_001175682.1\|3091871_3093323_+	sodium/pantothenate symporter	NA	NA	NA	NA
WP_001145849.1\|3093334_3094216_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_001219664.1\|3094876_3095842_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_000462905.1\|3095867_3096164_+	DNA-binding transcriptional regulator Fis	NA	NA	NA	NA
WP_001623424.1\|3098073_3098883_+	cytolethal distending toxin subunit B family protein	A5LH53	Enterobacteria_phage	1.6e-59	47.0
WP_023228120.1\|3099043_3099409_+	DUF1353 domain-containing protein	I1TQ41	Pseudomonas_phage	9.4e-15	38.2
WP_023228121.1\|3099585_3100128_-	glycoside hydrolase family 108 protein	A0A0U2S643	Escherichia_phage	4.0e-70	65.4
WP_001623421.1\|3100328_3101060_-	pertussis-like toxin subunit ArtA	A0A0U2KD26	Escherichia_phage	1.9e-59	51.2
WP_024148288.1\|3101075_3101501_-	subtilase	NA	NA	NA	NA
WP_023228124.1\|3102447_3102978_-\|tail	tail fiber assembly protein	S4TUB9	Salmonella_phage	4.3e-93	97.1
WP_149866814.1\|3102990_3104310_-\|tail	phage tail protein	Q8HAB4	Salmonella_phage	3.8e-183	79.6
WP_023228126.1\|3105240_3105822_-\|tail	phage tail protein I	V9IQK7	Stenotrophomonas_phage	7.7e-19	34.1
WP_023228127.1\|3105814_3106939_-\|plate	baseplate J/gp47 family protein	A0A0C5AEG2	Bacteriophage	3.0e-88	43.9
WP_021000619.1\|3106935_3107259_-	hypothetical protein	A0A067ZJ13	Vibrio_phage	6.0e-13	41.3
WP_001623398.1\|3107255_3107723_-\|tail	phage tail protein	NA	NA	NA	NA
WP_001623397.1\|3107719_3108340_-\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	1.3e-32	55.9
WP_001623396.1\|3108340_3109342_-	phage late control D	A0A0C5AJ59	Bacteriophage	1.8e-55	36.3
WP_001623395.1\|3109331_3109550_-	hypothetical protein	A0A0C5AEF4	Bacteriophage	3.2e-10	50.0
WP_077909340.1\|3109542_3111447_-\|tail	phage tail tape measure protein	A0A097I4X9	Vibrio_phage	5.6e-42	26.5
WP_001623392.1\|3112153_3112435_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_001623391.1\|3112444_3112966_-\|tail	phage major tail tube protein	A0A067ZJA9	Vibrio_phage	1.2e-47	53.2
WP_001623390.1\|3112978_3114448_-\|tail	major tail sheath protein	A0A059WKP9	Vibrio_phage	7.6e-148	54.5
WP_001623389.1\|3114447_3114747_-	hypothetical protein	NA	NA	NA	NA
WP_021000628.1\|3114746_3115232_-	hypothetical protein	A0A067ZIL8	Vibrio_phage	8.4e-19	36.0
WP_001623387.1\|3115228_3115573_-	hypothetical protein	A0A067ZJA6	Vibrio_phage	1.0e-18	43.9
WP_001623386.1\|3115569_3116034_-	hypothetical protein	NA	NA	NA	NA
WP_023228130.1\|3116034_3117078_-\|capsid	major capsid protein	A0A059WRQ2	Vibrio_phage	1.4e-71	44.9
WP_001623384.1\|3117089_3117476_-	hypothetical protein	NA	NA	NA	NA
WP_001623382.1\|3117486_3118551_-\|protease	Clp protease ClpP	A0A067ZG37	Vibrio_phage	1.7e-80	48.6
WP_023228131.1\|3118543_3120106_-\|portal	phage portal protein	A0A067ZJA4	Vibrio_phage	1.8e-187	64.3
WP_021000635.1\|3120102_3120342_-	hypothetical protein	A0A067ZJ01	Vibrio_phage	6.8e-14	54.8
WP_023228132.1\|3120353_3122213_-\|terminase	phage terminase large subunit family protein	A0A059WKL6	Vibrio_phage	1.3e-232	63.7
WP_024148290.1\|3122218_3122770_-	hypothetical protein	A0A067ZIZ9	Vibrio_phage	1.6e-18	38.2
WP_001623372.1\|3122769_3123360_-	ParB N-terminal domain-containing protein	A0A067ZI74	Vibrio_phage	1.5e-38	56.5
WP_024148291.1\|3123868_3124585_-	hypothetical protein	NA	NA	NA	NA
WP_023136440.1\|3124857_3125361_-	hypothetical protein	NA	NA	NA	NA
WP_023228134.1\|3125463_3126006_-	DUF2514 domain-containing protein	NA	NA	NA	NA
WP_023228135.1\|3126002_3126629_-	glycoside hydrolase family 19 protein	Q858F0	Salmonella_phage	1.3e-91	78.3
WP_023228136.1\|3126628_3126910_-\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	1.3e-35	79.6
WP_001623349.1\|3126896_3127286_-	hypothetical protein	K7PHB9	Enterobacterial_phage	1.1e-40	71.8
WP_024156063.1\|3127597_3128023_-	subtilase	NA	NA	NA	NA
WP_071604142.1\|3127949_3128504_-	hypothetical protein	A0A0U2KD26	Escherichia_phage	3.0e-49	64.5
WP_024156062.1\|3129465_3130302_-	antitermination protein	A0A1B5FPA5	Escherichia_phage	8.5e-128	84.8
WP_001623343.1\|3130298_3131147_-	hypothetical protein	F1C596	Cronobacter_phage	5.8e-124	75.5
WP_023228520.1\|3131146_3132115_-	phage DNA primase	A0A1B5FPA8	Escherichia_phage	1.0e-177	94.7
WP_001623340.1\|3132111_3133743_-	DEAD/DEAH box helicase	A0A1B5FPA4	Escherichia_phage	2.1e-284	87.1
WP_024148337.1\|3134165_3134462_-	hypothetical protein	A0A1B5FPB9	Escherichia_phage	2.9e-30	73.0
WP_023237655.1\|3134424_3134679_-	helix-turn-helix transcriptional regulator	A0A2H4JEY0	uncultured_Caudovirales_phage	5.7e-11	52.9
WP_000497764.1\|3134791_3135487_+	helix-turn-helix transcriptional regulator	F1C5C2	Cronobacter_phage	7.4e-85	67.5
WP_023228516.1\|3135666_3135984_+	hypothetical protein	A0A286S1T9	Klebsiella_phage	3.0e-17	51.0
WP_023228515.1\|3136167_3136353_+	hypothetical protein	NA	NA	NA	NA
WP_000267316.1\|3136540_3136750_+	hypothetical protein	NA	NA	NA	NA
WP_023228514.1\|3136730_3137090_+	hypothetical protein	A0A1B5FPB3	Escherichia_phage	8.9e-26	52.1
WP_001623336.1\|3137089_3137326_+	hypothetical protein	A0A286SGR4	Klebsiella_phage	1.1e-21	65.7
WP_001623335.1\|3137315_3137723_+	hypothetical protein	A0A286S1S2	Klebsiella_phage	5.1e-62	84.3
WP_001623334.1\|3137734_3138484_+	ORF6N domain-containing protein	A0A1B5FPC0	Escherichia_phage	6.6e-132	94.0
WP_001623333.1\|3138480_3139047_+	hypothetical protein	A0A088C4R7	Shewanella_sp._phage	3.7e-26	37.8
WP_023228513.1\|3139043_3139268_+	hypothetical protein	A0A1B5FPG2	Escherichia_phage	2.5e-18	66.2
WP_162096905.1\|3139363_3139477_+	hypothetical protein	A0A286S2B6	Klebsiella_phage	8.1e-10	83.8
WP_001193443.1\|3140299_3140542_+	excisionase family protein	A0A286S2A4	Klebsiella_phage	1.1e-22	68.4
WP_001623330.1\|3140567_3141899_+\|integrase	site-specific integrase	Q9XJG6	Enterobacteria_phage	2.8e-165	64.6
WP_001270724.1\|3141988_3142504_+	lipoprotein	NA	NA	NA	NA
WP_000027186.1\|3142733_3143462_+	arginine ABC transporter ATP-binding protein ArtP	G9BWD6	Planktothrix_phage	5.1e-28	35.8
3146654:3146675	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP019181

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection