CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_022651	Escherichia coli JJ1886 plasmid pJJ1886_5, complete sequence	0 crisprs	NA	0	1
NC_022649	Escherichia coli JJ1886 plasmid pJJ1886_2, complete sequence	0 crisprs	NA	0	0
NC_022661	Escherichia coli JJ1886 plasmid pJJ1886_1, complete sequence	0 crisprs	NA	0	0
NC_022648	Escherichia coli JJ1886, complete sequence	2 crisprs	DinG,cas3,RT,DEDDh,c2c9_V-U4,csa3	1	14
NC_022650	Escherichia coli JJ1886 plasmid pJJ1886_4, complete sequence	0 crisprs	NA	0	0
NC_022662	Escherichia coli JJ1886 plasmid pJJ1886_3, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_022648_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022648_1

766021-766162

Orphan

Consensus_repeat	Method
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022648_1

>merge|NC_022648|1|766021-766162|CRISPRCasFinder
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAGAAACCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAAACAGCGCCGGATGCGGCGTGAATGCCTTATCCGGCCTACAAAAGAAATGCAG

>NC_022648|1|1|766021-766162|CRISPRCasFinder
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAG	AAACCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAAACAGC
GCCGGATGCGGCGTGAATGCCTTATCCGGCCTACAAAAGAAATGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_022648.1\|WP_000099866.1\|769151_770369_+\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	unknown	unknown	gnl\|CDD\|235571
NC_022648.1\|WP_001181475.1\|766335_769137_+\|2-oxoglutarate-dehydrogenase-E1-component	unknown	unknown	gnl\|CDD\|236499
NC_022648.1\|WP_000254365.1\|763128_763476_+\|succinate-dehydrogenase-membrane-anchor-subunit	unknown	unknown	gnl\|CDD\|181901
NC_022648.1\|WP_000648957.1\|775426_778060_+\|mannosylglycerate-hydrolase	unknown	unknown	gnl\|CDD\|182093
NC_022648.1\|WP_000025458.1\|771628_772498_+\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
NC_022648.1\|WP_000126143.1\|759396_760707_+\|TRAP-transporter-large-permease	unknown	unknown	gnl\|CDD\|224509
NC_022648.1\|WP_000509910.1\|772601_773324_-\|mannosyl-D-glycerate-transport/metabolism-system-transcriptional-repressor-MngR	unknown	unknown	gnl\|CDD\|182065
NC_022648.1\|WP_000725054.1\|778257_779451_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_022648.1\|WP_000775540.1\|763475_765242_+\|succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|181594
NC_022648.1\|WP_000568275.1\|782577_783717_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|184965
NC_022648.1\|WP_001237779.1\|758935_759397_+\|TRAP-transporter-small-permease	unknown	unknown	gnl\|CDD\|225632
NC_022648.1\|WP_000263355.1\|762730_763135_+\|succinate-dehydrogenase-cytochrome-b556-subunit	unknown	unknown	gnl\|CDD\|181900
NC_022648.1\|WP_001305582.1\|762242_762350_-\|hypothetical-protein	unknown	unknown	unknown
NC_022648.1\|WP_000735581.1\|757907_758876_+\|C4-dicarboxylate-ABC-transporter	unknown	unknown	gnl\|CDD\|270387
NC_022648.1\|WP_001048602.1\|770462_771629_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NC_022648.1\|WP_000884361.1\|780993_782562_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|185052
NC_022648.1\|WP_000399432.1\|756683_757880_+\|UxaA-family-hydrolase	unknown	unknown	gnl\|CDD\|377287
NC_022648.1\|WP_001235263.1\|765257_765974_+\|succinate-dehydrogenase-iron-sulfur-subunit-SdhB	unknown	unknown	gnl\|CDD\|235652
NC_022648.1\|WP_001531490.1\|773492_775409_+\|PTS-2-O-a-mannosyl-D-glycerate-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|182066
NC_022648.1\|WP_000785832.1\|760753_762037_-\|citrate-(Si)-synthase	unknown	unknown	gnl\|CDD\|180164

Protein	Function_ID	Function_description	E-value
NC_022648.1\|WP_000099866.1\|769151_770369_+\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	gnl\|CDD\|235571	PRK05704, PRK05704, 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase.	0
NC_022648.1\|WP_001181475.1\|766335_769137_+\|2-oxoglutarate-dehydrogenase-E1-component	gnl\|CDD\|236499	PRK09404, sucA, 2-oxoglutarate dehydrogenase E1 component; Reviewed.	0
NC_022648.1\|WP_000254365.1\|763128_763476_+\|succinate-dehydrogenase-membrane-anchor-subunit	gnl\|CDD\|181901	PRK09488, sdhD, succinate dehydrogenase membrane anchor subunit.	5.54037e-58
NC_022648.1\|WP_000648957.1\|775426_778060_+\|mannosylglycerate-hydrolase	gnl\|CDD\|182093	PRK09819, PRK09819, mannosylglycerate hydrolase.	0
NC_022648.1\|WP_000126143.1\|759396_760707_+\|TRAP-transporter-large-permease	gnl\|CDD\|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	2.11617e-118
NC_022648.1\|WP_000509910.1\|772601_773324_-\|mannosyl-D-glycerate-transport/metabolism-system-transcriptional-repressor-MngR	gnl\|CDD\|182065	PRK09764, PRK09764, GntR family transcriptional regulator.	1.54929e-163
NC_022648.1\|WP_000725054.1\|778257_779451_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.01578e-17
NC_022648.1\|WP_000775540.1\|763475_765242_+\|succinate-dehydrogenase-flavoprotein-subunit	gnl\|CDD\|181594	PRK08958, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	0
NC_022648.1\|WP_000568275.1\|782577_783717_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|184965	PRK15003, PRK15003, cytochrome d ubiquinol oxidase subunit II.	0
NC_022648.1\|WP_001237779.1\|758935_759397_+\|TRAP-transporter-small-permease	gnl\|CDD\|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	2.66483e-21
NC_022648.1\|WP_000263355.1\|762730_763135_+\|succinate-dehydrogenase-cytochrome-b556-subunit	gnl\|CDD\|181900	PRK09487, sdhC, succinate dehydrogenase cytochrome b556 subunit.	3.50714e-82
NC_022648.1\|WP_000025458.1\|771628_772498_+\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NC_022648.1\|WP_000735581.1\|757907_758876_+\|C4-dicarboxylate-ABC-transporter	gnl\|CDD\|270387	cd13669, PBP2_TRAP_TM0322_like, Periplasmic component of TRAP-type C4-dicarboxylate transport system TM0322 from Thermotoga maritima and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the hyperthermophilic bacterium Thermotoga maritima TRAP-type C4-dicarboxylate transport system TM0322 and its closely related proteins. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.46494e-145
NC_022648.1\|WP_001048602.1\|770462_771629_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NC_022648.1\|WP_000884361.1\|780993_782562_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|185052	PRK15097, PRK15097, cytochrome bd-I ubiquinol oxidase subunit CydA.	0
NC_022648.1\|WP_000399432.1\|756683_757880_+\|UxaA-family-hydrolase	gnl\|CDD\|377287	pfam04295, GD_AH_C, D-galactarate dehydratase / Altronate hydrolase, C-terminus. Family members include the C termini of D-galactarate dehydratase (EC:4.2.1.42) which is thought to catalyze the reaction D-galactarate = 5-keto-4-deoxy-D-glucarate + H2O, and altronate hydrolase (altronic acid hydratase, EC:4.2.1.7), which catalyzes D-altronate = 2-keto-2-deoxygluconate + H2O. As purified, both enzymes are catalytically inactive in the absence of added Fe2+, Mn2+, and beta-mercaptoethanol. Synergistic activation of altronate hydrolase activity is seen in the presence of both iron and manganese ions, suggesting that the enzyme may have two ion binding sites. Mn2+ appears to be part of the enzyme active centre, but the function of the single bound Fe2+ ion is unknown. The hydratase has no Fe-S core.	5.6924e-134
NC_022648.1\|WP_001235263.1\|765257_765974_+\|succinate-dehydrogenase-iron-sulfur-subunit-SdhB	gnl\|CDD\|235652	PRK05950, sdhB, succinate dehydrogenase iron-sulfur subunit; Reviewed.	3.48257e-167
NC_022648.1\|WP_001531490.1\|773492_775409_+\|PTS-2-O-a-mannosyl-D-glycerate-transporter-subunit-IIABC	gnl\|CDD\|182066	PRK09765, PRK09765, PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional.	0
NC_022648.1\|WP_000785832.1\|760753_762037_-\|citrate-(Si)-synthase	gnl\|CDD\|180164	PRK05614, gltA, citrate synthase.	0

>NC_022648.1|WP_001235263.1|765257_765974_+|succinate-dehydrogenase-iron-sulfur-subunit-SdhB
MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKEKDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRDLVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCPSFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPKGLNPTRAIGHIKSMLLQRNA
>NC_022648.1|WP_000775540.1|763475_765242_+|succinate-dehydrogenase-flavoprotein-subunit
MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPPKIRTY
>NC_022648.1|WP_000254365.1|763128_763476_+|succinate-dehydrogenase-membrane-anchor-subunit
MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELTYEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALVVYVIYGFVVVWGV
>NC_022648.1|WP_000263355.1|762730_763135_+|succinate-dehydrogenase-cytochrome-b556-subunit
MWALFMIRNVKKQRPVNLDLQTIRFPVTAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVVLSLLAGVLVW
>NC_022648.1|WP_001305582.1|762242_762350_-|hypothetical-protein
MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV
>NC_022648.1|WP_000785832.1|760753_762037_-|citrate-(Si)-synthase
MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFDPGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREIAAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKMLEEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYAQRDFKSDIKK
>NC_022648.1|WP_000126143.1|759396_760707_+|TRAP-transporter-large-permease
MTALSELLAGSWLDNWLMIIPLMFVCLFINMPVWLAMFCGILTYFLCYSNVPLMVAIQRLIATTQTPSLLAIPFFILLGTLMSYTGIAARILQIANVLIGRMRGGLGGANILVSTMMGGVSASNLADAAMLSRMMVPEMEQKGYSRGFAAAITASGSLITPIIPPGIALILYGLVADVSIGSMFMAGILPGLLCSAMLIVTVWLVAIRRGLKPSSEHWPKPKEVSVALVQAWPALFLIVAVIGGIRANIFTPTEAGAVAVLLVMFIGFVIYRELKISHVFTALSETARSTASVMLIIMASAALGWIFSLERAGITVAEFVTSLTDNKYVFLLIINLLLLVLGMFLEGSAILLILVPLLKPVVAHFGIDPVHFGIIMILNLSLGTLSPPVGTVMLLVCNTVQVSVGQFMREAVPLLISLILLLLVITYIPAISLLLV
>NC_022648.1|WP_001237779.1|758935_759397_+|TRAP-transporter-small-permease
MRLLGKMIEVAAVLTLFILVIMTIAAVIMRYCFHMPLQWTEEVSGLLMIWVVMFGAVVAERDNTHLSIPFLADALTSRGQRILAFLVSLMSIILLVVMAWSAWKLAAGTAFKTTQILKISWFWIDIAVTVGAIGVACFTALQLIKKTPRKEGE
>NC_022648.1|WP_000735581.1|757907_758876_+|C4-dicarboxylate-ABC-transporter
MKKLLTPLLFLLALFSPMLNAAPVTIKIAYESNPGEPADTVVKHWAELVKKKSNGDIVFELYPSSQLGSKQDITEQALMGMNIITISDVGFLTDYDADLGILFGPYLTEDPQKLFAIYASDWFKQKEQKLREKGVHIVMSNYLYGTRQIIAKKPIRTPEDLKGMKIRVPNNVMQIKAIEAMGATPTPMPLGDVYPALTQGMIDGVENPVSVLYGQKLHEQAKYLSMVNYLTNTSLWLGGEAFFSTLTPAQLDIIHQTAYEAGLYSQKITTEQDATMLKTMQEQGVEIIYPDVAPFKEKALKVYQQFPEWTPGLYDTIQQQLK
>NC_022648.1|WP_000399432.1|756683_757880_+|UxaA-family-hydrolase
MEGYVRQNGRPGIRNTVQVIFMVECASHVAKKIAEGFPCHDVQYFGFSGCYPSDYGYRLVKNLATHSNVGGVLIISLGCENFDRRRLEQEVRESGRPCHTLVIQENKGTTNTITLGKQLVAEMLEQLADTPRCILNWSDLVVGTICGGSDGTSGITGNPAVGRAFDQLLEKGATCIFEESGELLGCEQHMMSRAASSQARDAIEVAMTKAERYYSLMGLGSFSNGNAEGGLTTQEEKSLGAYTKSGDALIAGVILPTQQTPFPGLWLMDVVPDGEPRFGYPNINDSSEALELIASGCHMVLFTTGRGSVIGSVIAPIIKVCNNPQTWEHLSDDMDVNAGRVISEGATLDDIADDIMQVIEHVANGQYCAAERLEHQEFVLTYKAFDYSKSAVCRADPR
>NC_022648.1|WP_001181475.1|766335_769137_+|2-oxoglutarate-dehydrogenase-E1-component
MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAISEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGYMSVHQKQQQDLVNDALNVE
>NC_022648.1|WP_000099866.1|769151_770369_+|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase
MSSVDILVPDLPESVADATVATWHKKPGDVVVRDEVLVEIETDKVVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQQASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAPAAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV
>NC_022648.1|WP_001048602.1|770462_771629_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK
>NC_022648.1|WP_000025458.1|771628_772498_+|succinate--CoA-ligase-subunit-alpha
MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPTLDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYEAVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEAAAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRSLADIGEALKTVLK
>NC_022648.1|WP_000509910.1|772601_773324_-|mannosyl-D-glycerate-transport/metabolism-system-transcriptional-repressor-MngR
MGHKPLYRQIADRIREQITCGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVETHSEVLIFEVIPADNFLQQQLQISEQDRVWHVKRVRYRKQKPVALEETWMPLALFPDLTWQVMENSKYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGQVFEYSRNAFNTDDYKFTLIAQRKSPR
>NC_022648.1|WP_001531490.1|773492_775409_+|PTS-2-O-a-mannosyl-D-glycerate-transporter-subunit-IIABC
MNLTTLTHRDALCLNVRFTSREEAIHALTQRLAALGKISSTEQFLEEVYCRESLGPTALGEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMKLLTALTTRLADDELRARIQSATTPDELLSALDDKGDAQHTASFSYAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNIYVEKQGANGIEERLTAEQLNSATACIFAAEVAIKESERFNGIPALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMYRKLGGGMLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGNNALLLGAILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLIWRHHAVKHGNYLTDGVMP
>NC_022648.1|WP_000648957.1|775426_778060_+|mannosylglycerate-hydrolase
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILEDYFAVKPENKDRVKKLVEGGKLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDKTEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMEKLREIYPQRKFVMSRFEEVFEQIEAQRESLAILKGEFIDGKYMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFDYHHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNLMPWPREEVINTTVRLRGSQFNLRDGRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQISQIVPSMGYRTLYIEANQLGNVVTPKSKTEGILENAFWQIALNEDGSLRLVDKDSGVRYDRVFQIEEGSDDGDEYDYSPAKEEWAITSANAKPQYDIIHEAWQSRAIIRYEIAVPRNLSERRAKQCSGRVGVETVITLSHNSRRIDADINLDNQADDHRIRVLIPTPFNTDVVLADTQFGSLTRPVKDCAMNVWQQEGWKEAPVPVWNMLNYAVLQEGRNGIAVFSEGLREFEVIGEENKTFAITLLRGVGLLGKEDLLLRPGRPSGIKMPVSDSQLRGSFSCRLSLFSYIGTPVTAGVAQQARAWLTPVQCYNKIPWDAMKLNKAKFNVPESYSLLKMPPVGCLISALKKAEDRQELILRLFNPAELTSCDATVAFSRKVMTCTETMMNERFNTEKNEVLKELALFLPGQSRTFSYRIV
>NC_022648.1|WP_000725054.1|778257_779451_+|tetratricopeptide-repeat-protein
MKKIVLPVALALLGMNAGAYAADVSIDILSATVKDKRIEGASVTLQRNGAQSVSGITNTSGSISLGTSFADNKDALLIVKKEGYSNLVVKCPCAGMTYAISPVMTNLDGMRVVLSWGEKPFDLDSHLIFPGGHIYFDSKEGTDANLDVDDTDSYGPETVTISKKHFGESYIYAVQDYSNKGLPNSNYLSASKAKVFVYVGSSLVRSYSVPAGKRGNIWTVFKLNPNGEFEDINSVTSANFNGTTLDVRDLATVIMPATDSSAPASPAMQNSGDTQLARKYNREGEAVYKTGQLEQAIQLFQQATELDGNYGQAFSNLGLAYQKNGNIAEAIWANRKAISLASGVNAATTRANSYYNIAKIYETSGQNAEALQHYQLAYTEKNKPSYEEAIARVKTKM
>NC_022648.1|WP_000884361.1|780993_782562_+|cytochrome-ubiquinol-oxidase-subunit-I
MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSGKQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLMAFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFNFETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKRSFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPDQEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSGSTDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRIMVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQPWAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGRYHFEQSSTTTQPAR
>NC_022648.1|WP_000568275.1|782577_783717_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDTERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPVGFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGNFFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALAGVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLPLLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQLTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY

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Crispr_ID: NC_022648_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022648_2

932228-932310

Orphan

I-F

Consensus_repeat	Method
AGTTCACTGCCGTACAGGCAGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022648_2

>merge|NC_022648|2|932228-932310|CRISPRCasFinder
AGTTCACTGCCGTACAGGCAGCTTAGAAATTGCCGCGGATCCTGTCTGCCAATAATGACAAGTTCACTGCCGTACAGGCAGAT

>NC_022648|2|2|932228-932310|CRISPRCasFinder
AGTTCACTGCCGTACAGGCAGCT	TAGAAATTGCCGCGGATCCTGTCTGCCAATAATGACA
AGTTCACTGCCGTACAGGCAGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_022648.1\|WP_000067797.1\|944585_945929_+\|replication-associated-recombination-protein-RarA	unknown	unknown	gnl\|CDD\|237355
NC_022648.1\|WP_000886683.1\|946019_947312_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NC_022648.1\|WP_000228473.1\|939069_939564_+\|leucine-responsive-transcriptional-regulator-Lrp	unknown	unknown	gnl\|CDD\|183009
NC_022648.1\|WP_000410785.1\|928841_929066_-\|cold-shock-like-protein-CspD	unknown	unknown	gnl\|CDD\|77494
NC_022648.1\|WP_000077041.1\|939698_943805_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
NC_022648.1\|WP_001241674.1\|933203_933908_-\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NC_022648.1\|WP_001040187.1\|932700_932919_-\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
NC_022648.1\|WP_000488716.1\|921828_922524_-\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
NC_022648.1\|WP_001202204.1\|933949_935671_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865
NC_022648.1\|WP_000458841.1\|918718_920371_-\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
NC_022648.1\|WP_000934041.1\|929739_932016_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828
NC_022648.1\|WP_000599803.1\|922948_924607_+\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
NC_022648.1\|WP_001295343.1\|943963_944575_+\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|129638
NC_022648.1\|WP_000188152.1\|926822_928769_+\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl\|CDD\|182528
NC_022648.1\|WP_001385255.1\|937560_938526_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
NC_022648.1\|WP_000746478.1\|925710_926826_+\|macrolide-transporter-subunit-MacA	unknown	unknown	gnl\|CDD\|183211
NC_022648.1\|WP_001043561.1\|935671_937438_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870
NC_022648.1\|WP_000520781.1\|929388_929709_+\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NC_022648.1\|WP_001351020.1\|924603_925560_-\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|225537
NC_022648.1\|WP_000491137.1\|920514_921414_-\|L-lysine-exporter-LysO	unknown	unknown	gnl\|CDD\|225287

Protein	Function_ID	Function_description	E-value
NC_022648.1\|WP_000067797.1\|944585_945929_+\|replication-associated-recombination-protein-RarA	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NC_022648.1\|WP_000886683.1\|946019_947312_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NC_022648.1\|WP_000228473.1\|939069_939564_+\|leucine-responsive-transcriptional-regulator-Lrp	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117
NC_022648.1\|WP_000410785.1\|928841_929066_-\|cold-shock-like-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
NC_022648.1\|WP_000077041.1\|939698_943805_+\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
NC_022648.1\|WP_001241674.1\|933203_933908_-\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.92039e-139
NC_022648.1\|WP_001040187.1\|932700_932919_-\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
NC_022648.1\|WP_000488716.1\|921828_922524_-\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	7.82992e-144
NC_022648.1\|WP_001202204.1\|933949_935671_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NC_022648.1\|WP_000458841.1\|918718_920371_-\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NC_022648.1\|WP_000934041.1\|929739_932016_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
NC_022648.1\|WP_000599803.1\|922948_924607_+\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
NC_022648.1\|WP_001295343.1\|943963_944575_+\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
NC_022648.1\|WP_000188152.1\|926822_928769_+\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
NC_022648.1\|WP_001385255.1\|937560_938526_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
NC_022648.1\|WP_000746478.1\|925710_926826_+\|macrolide-transporter-subunit-MacA	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
NC_022648.1\|WP_001043561.1\|935671_937438_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NC_022648.1\|WP_000520781.1\|929388_929709_+\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.48686e-49
NC_022648.1\|WP_001351020.1\|924603_925560_-\|DUF535-domain-containing-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	3.43529e-131
NC_022648.1\|WP_000491137.1\|920514_921414_-\|L-lysine-exporter-LysO	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	3.40497e-117

>NC_022648.1|WP_000934041.1|929739_932016_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>NC_022648.1|WP_000520781.1|929388_929709_+|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>NC_022648.1|WP_000410785.1|928841_929066_-|cold-shock-like-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>NC_022648.1|WP_000188152.1|926822_928769_+|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLEWKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNATGGTEPVVNTASGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>NC_022648.1|WP_000746478.1|925710_926826_+|macrolide-transporter-subunit-MacA
MKKRKTVKKRYVIAMVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDNAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKINDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>NC_022648.1|WP_001351020.1|924603_925560_-|DUF535-domain-containing-protein
MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAELTFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFCS
>NC_022648.1|WP_000599803.1|922948_924607_+|ATP-dependent-endonuclease
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENIPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>NC_022648.1|WP_000488716.1|921828_922524_-|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRN
>NC_022648.1|WP_000491137.1|920514_921414_-|L-lysine-exporter-LysO
MFSGLLIILVPLIVGYLIPLRQKAALRVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSTTVILLCNIAALMWLERGLPWSNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
>NC_022648.1|WP_000458841.1|918718_920371_-|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIATLQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIIGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
>NC_022648.1|WP_001040187.1|932700_932919_-|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>NC_022648.1|WP_001241674.1|933203_933908_-|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCDEFIRHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLSNNFWVPRCLFSPQE
>NC_022648.1|WP_001202204.1|933949_935671_-|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPKVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGIYLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMCEKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL
>NC_022648.1|WP_001043561.1|935671_937438_-|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLFLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQTALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGRYAELSVAGGPFATLLAHRQEEI
>NC_022648.1|WP_001385255.1|937560_938526_-|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNTDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>NC_022648.1|WP_000228473.1|939069_939564_+|leucine-responsive-transcriptional-regulator-Lrp
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>NC_022648.1|WP_000077041.1|939698_943805_+|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQSTVAWQPVPGPQTGEPVIAPAPEGYPQQPQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYATAAEQPAQQPYYAPAPEQAVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPTRPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNTEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQQQYQQPQQPVAQQPQYQQPQQPVTQQPQYQQPQQPVVPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>NC_022648.1|WP_001295343.1|943963_944575_+|outer-membrane-lipoprotein-chaperone-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>NC_022648.1|WP_000067797.1|944585_945929_+|replication-associated-recombination-protein-RarA
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAVGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVYLLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>NC_022648.1|WP_000886683.1|946019_947312_+|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	12111-12158	8	0.833
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	424237-424284	8	0.833
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7391-7438	10	0.792
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84215-84262	10	0.792
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87125-87172	10	0.792
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229237-229284	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229338-229385	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229439-229486	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239731-239778	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239832-239879	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239933-239980	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15006-15053	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230643-230690	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230744-230791	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230845-230892	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211613-211660	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211714-211761	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211815-211862	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_AP023207	Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence	31250-31297	11	0.771
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	3371-3418	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4012-4059	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4113-4160	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208980-209027	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	3370-3417	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4011-4058	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4112-4159	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219474-219521	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	3370-3417	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4011-4058	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4112-4159	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210308-210355	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	3370-3417	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4011-4058	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4112-4159	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191263-191310	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	MT230402	Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence	270-317	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	101195-101242	12	0.75
NC_022648_1	1.1\|766068\|48\|NC_022648\|CRISPRCasFinder	766068-766115	48	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	158-205	13	0.729

1. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 8, identity: 0.833

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gactcgtaggcctgataagacgcgccagcgtcgcatcaggcaccgaac	Protospacer
.* .********************* ****************   *.*

2. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 8, identity: 0.833

aaaccgtaggcctgataagacgcgcaagcgtcg-catcaggcaaacagc	CRISPR spacer
aacctgtaggcctgataagacgcgcaagcgtcgccatcaggcatctca-	Protospacer
** *.**************************** *********  . .

3. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 10, identity: 0.792

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gttttgtaggcatgataagacgcgccagcgtcgcatcaggcatccggc	Protospacer
.  ..****** ************* ****************  *.**

4. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 10, identity: 0.792

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gttttgtaggcatgataagacgcgccagcgtcgcatcaggcatccggc	Protospacer
.  ..****** ************* ****************  *.**

5. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 10, identity: 0.792

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
attttgtaggcctgataagacgcggcagcgtcgcatcaggcatcgtgc	Protospacer
*  ..*******************  ****************    **

6. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

7. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

8. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

9. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

10. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

11. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

12. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctggt	Protospacer
.. .******* ************* ****************  ..*.

13. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

14. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

15. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

16. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

17. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

18. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

19. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_AP023207 (Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
cggctgtaggcctgataagacgcgacagcgtcgcatcaggcattgatt	Protospacer
 ..*.*******************  ****************   * .

20. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

21. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

22. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

23. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

24. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

25. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

26. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

27. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

28. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

29. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

30. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

31. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

32. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

33. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

34. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

35. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

36. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to MT230402 (Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggtttgtaggcctgataagacgcgacagcgtcgcatcaggcattgatt	Protospacer
.. ..*******************  ****************   * .

37. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
taatacaaggcctgataagacgcgccagcgtcgcatcaggcgctgaat	Protospacer
 **.   ****************** ***************.   *..

38. spacer 1.1|766068|48|NC_022648|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gtctngtaggcctgataagacgcgtcagcgtcgcatcaggcttcaatt	Protospacer
.  . *******************. ***************    * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

929388 : 1041742

132

Enterobacteria_phage(41.84%)

portal,head,terminase,plate,protease,transposase,tRNA,integrase,holin,tail,capsid

attL 1024787:1024802|attR 1046661:1046676

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000520781.1\|929388_929709_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.6e-13	44.4
WP_000934041.1\|929739_932016_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.9e-166	42.5
WP_001040187.1\|932700_932919_-	translation initiation factor IF-1	NA	NA	NA	NA
WP_001241674.1\|933203_933908_-\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001202204.1\|933949_935671_-	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	W8CYL7	Bacillus_phage	1.4e-20	25.0
WP_001043561.1\|935671_937438_-	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	4.1e-23	24.3
WP_001385255.1\|937560_938526_-	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	1.9e-62	44.6
WP_000228473.1\|939069_939564_+	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_000077041.1\|939698_943805_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	1.2e-86	48.7
WP_001295343.1\|943963_944575_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_000067797.1\|944585_945929_+	replication-associated recombination protein RarA	G3MBE0	Bacillus_virus	2.1e-80	40.8
WP_000886683.1\|946019_947312_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.5e-94	48.2
WP_000078916.1\|947617_947758_-	Hok/Gef family protein	A0A0A7NPZ4	Enterobacteria_phage	1.5e-18	97.8
WP_000488106.1\|947949_948210_-	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_000132830.1\|948250_949360_-	phage late control D family protein	A0A0A7NQ97	Enterobacteria_phage	1.3e-195	94.9
WP_000005447.1\|949517_950702_+\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	8.4e-222	97.5
WP_000290462.1\|950701_951214_+\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	1.5e-90	97.1
WP_000651577.1\|951269_951644_+\|tail	tail protein	A0A0A7NPZ0	Enterobacteria_phage	9.9e-36	71.5
WP_000333503.1\|951652_951808_+\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	9.7e-22	96.1
WP_000853410.1\|951794_954602_+\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	0.0e+00	90.1
WP_000979945.1\|954614_955103_+\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	1.4e-85	99.4
WP_000905061.1\|955131_955731_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	3.8e-98	98.9
WP_023363133.1\|955958_956744_+	hypothetical protein	Q858V4	Yersinia_virus	1.1e-108	76.6
WP_000972134.1\|957311_957845_-\|tail	tail fiber assembly protein	C9DGR0	Escherichia_phage	4.2e-96	98.9
WP_021538277.1\|957847_959833_-\|tail	phage tail fiber protein	A0A0A7NV63	Enterobacteria_phage	3.2e-173	86.0
WP_000071703.1\|959835_960366_-\|tail	phage tail protein I	A0A0A7NPV1	Enterobacteria_phage	3.6e-92	98.2
WP_001111954.1\|960358_961255_-\|plate	baseplate assembly protein	A0A0A7NPY5	Enterobacteria_phage	3.3e-154	97.7
WP_000213444.1\|961258_961609_-\|plate	baseplate assembly protein	A0A0A7NQ90	Enterobacteria_phage	3.5e-59	99.1
WP_001271941.1\|961605_962187_-\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	3.3e-102	98.4
WP_000356366.1\|962183_962819_-	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	4.1e-114	99.5
WP_000921127.1\|962811_963279_-\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	3.5e-83	95.5
WP_023363135.1\|963302_965180_-	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	9.3e-300	80.3
WP_000780577.1\|965318_965714_-	DUF2570 domain-containing protein	A0A0A7NPY2	Enterobacteria_phage	1.0e-59	93.3
WP_000072341.1\|965710_966103_-	M15 family metallopeptidase	A0A0A7NQ86	Enterobacteria_phage	1.9e-69	96.9
WP_001342221.1\|966099_966423_-\|holin	holin	A0A0A7NRY9	Enterobacteria_phage	1.7e-47	93.5
WP_000864901.1\|966425_966626_-\|tail	tail protein	A0A0A7NV57	Enterobacteria_phage	3.5e-32	100.0
WP_000063100.1\|966625_967120_-\|head	head completion/stabilization protein	A0A0A7NPU2	Enterobacteria_phage	1.9e-87	97.0
WP_000632309.1\|967221_968022_-\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	6.9e-127	89.1
WP_001055083.1\|968066_969119_-\|capsid	phage major capsid protein, P2 family	A0A0A7NQ82	Enterobacteria_phage	1.4e-188	94.3
WP_001262655.1\|969142_969979_-\|capsid	phage capsid scaffolding protein	A0A0A7NRY7	Enterobacteria_phage	2.7e-150	99.6
WP_000613780.1\|970133_971885_+\|terminase	terminase	A0A0A7NV54	Enterobacteria_phage	0.0e+00	97.8
WP_000087814.1\|971884_972931_+\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	2.2e-202	99.7
WP_000236495.1\|972945_973470_-	hypothetical protein	NA	NA	NA	NA
WP_001068329.1\|974193_974691_+	DUF4760 domain-containing protein	NA	NA	NA	NA
WP_000193205.1\|974730_975573_+	hypothetical protein	NA	NA	NA	NA
WP_000211282.1\|975656_975971_-	plasmid partition protein	A0A0A7NPT5	Enterobacteria_phage	4.1e-19	52.3
WP_000686485.1\|975975_976935_-	recombinase	A0A0A7NPX4	Enterobacteria_phage	4.2e-179	99.1
WP_000123489.1\|977011_979834_-	replication endonuclease	A0A0A7NQ77	Enterobacteria_phage	0.0e+00	98.4
WP_000599382.1\|979840_980206_-	hypothetical protein	A0A0A7NRY1	Enterobacteria_phage	1.7e-61	97.5
WP_023142408.1\|980202_980820_-	hypothetical protein	S5MQL6	Escherichia_phage	1.5e-09	42.0
WP_000104290.1\|980831_981131_-	hypothetical protein	A0A0A7NRX6	Enterobacteria_phage	2.4e-40	88.9
WP_000153700.1\|981127_981394_-	winged helix-turn-helix transcriptional regulator	A0A0A7NV47	Enterobacteria_phage	2.0e-30	75.9
WP_000985157.1\|981390_981594_-	hypothetical protein	A0A0A7NPS8	Enterobacteria_phage	2.5e-25	83.6
WP_000543036.1\|981617_982028_-	hypothetical protein	NA	NA	NA	NA
WP_000021715.1\|982121_982235_-	hypothetical protein	A0A0A7NPW7	Enterobacteria_phage	1.8e-09	89.2
WP_000514277.1\|982231_982474_-	DUF4754 family protein	A0A0A7NQ71	Enterobacteria_phage	2.3e-38	100.0
WP_000159455.1\|982485_982764_-	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	3.1e-34	79.3
WP_000776267.1\|982774_983125_-	DUF4761 family protein	A0A0A7NV42	Enterobacteria_phage	8.1e-56	93.1
WP_001287828.1\|983262_983454_+	hypothetical protein	NA	NA	NA	NA
WP_000856387.1\|983460_983883_-	hypothetical protein	NA	NA	NA	NA
WP_001204236.1\|983887_984409_-	transcriptional regulator	NA	NA	NA	NA
WP_001368591.1\|984513_984855_+	helix-turn-helix transcriptional regulator	Q1JS45	Enterobacteria_phage	4.7e-16	51.2
WP_000023739.1\|984924_985917_+\|integrase	tyrosine-type recombinase/integrase	A0A0F7LBR0	Escherichia_phage	1.3e-103	56.2
WP_000850306.1\|986216_988661_+	dimethylsulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	6.6e-221	49.8
WP_000213098.1\|988671_989289_+	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	5.0e-77	60.6
WP_000534666.1\|989290_990154_+	dimethyl sulfoxide reductase anchor subunit DmsC	NA	NA	NA	NA
WP_000165876.1\|990189_990816_-	hydrolase	NA	NA	NA	NA
WP_000109283.1\|991129_992278_+	MFS transporter	NA	NA	NA	NA
WP_000111043.1\|992374_993115_-	pyruvate formate lyase 1-activating protein	A0A2P0VNQ0	Tetraselmis_virus	8.0e-21	26.5
WP_001292822.1\|993306_995589_-	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.0e-162	41.5
WP_001295917.1\|995643_996501_-	formate transporter FocA	NA	NA	NA	NA
WP_000194832.1\|996906_998667_-	30S ribosomal protein S12 methylthiotransferase accessory protein YcaO	NA	NA	NA	NA
WP_000642852.1\|998796_999489_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_000057158.1\|999687_1000776_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	2.7e-81	46.8
WP_000445240.1\|1000846_1002130_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000904922.1\|1002385_1002958_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	4.6e-85	85.2
WP_063269479.1\|1003017_1003542_+\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	1.8e-35	48.6
WP_000072165.1\|1003541_1004156_+\|tail	tail assembly protein	Q9MCR5	Enterobacteria_phage	2.5e-60	60.5
WP_023142129.1\|1004162_1004624_-\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	3.9e-34	50.0
WP_023363137.1\|1004634_1005882_-\|tail	tail protein	A0A0K2FIZ6	Escherichia_phage	2.0e-40	43.7
WP_000138756.1\|1005884_1006463_-\|tail	phage tail protein I	A4JWL7	Burkholderia_virus	1.7e-66	66.8
WP_001219098.1\|1006455_1007559_-\|plate	baseplate protein	Q6QI99	Burkholderia_phage	1.4e-106	55.2
WP_000859111.1\|1007549_1007897_-\|plate	baseplate protein	Q6QIA0	Burkholderia_phage	5.9e-35	62.4
WP_000148266.1\|1007951_1008548_-\|plate	phage baseplate assembly protein V	A4JWL4	Burkholderia_virus	3.2e-36	45.2
WP_000808007.1\|1008544_1009699_-	phage late control D family protein	Q6QIA2	Burkholderia_phage	1.9e-85	47.6
WP_012602373.1\|1009686_1009902_-	membrane protein	Q6QIA3	Burkholderia_phage	1.2e-17	57.1
WP_000458387.1\|1009898_1010783_-\|tail	phage tail protein	A4JWL1	Burkholderia_virus	6.8e-51	47.9
WP_000016538.1\|1010782_1013734_-\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	9.8e-86	29.9
WP_001202894.1\|1013809_1013968_-\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_000084213.1\|1013891_1014227_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_000110114.1\|1014324_1014606_-	hypothetical protein	NA	NA	NA	NA
WP_000034294.1\|1014608_1015130_-\|tail	phage major tail tube protein	A4JWK6	Burkholderia_virus	1.8e-67	67.6
WP_000729834.1\|1015129_1016557_-\|tail	tail protein	A4JWK5	Burkholderia_virus	4.5e-214	76.3
WP_012602372.1\|1016546_1016801_-	hypothetical protein	NA	NA	NA	NA
WP_001101804.1\|1016797_1017262_-	hypothetical protein	Q6QIB2	Burkholderia_phage	9.1e-39	51.7
WP_000271668.1\|1017261_1017708_-	DUF1320 domain-containing protein	A4JWK2	Burkholderia_virus	2.2e-34	52.3
WP_000537457.1\|1017709_1018048_-	DUF2190 family protein	NA	NA	NA	NA
WP_001286908.1\|1018057_1019011_-	hypothetical protein	A4JWK0	Burkholderia_virus	3.4e-64	43.8
WP_001273074.1\|1019025_1020141_-	hypothetical protein	A4JWJ9	Burkholderia_virus	9.4e-98	51.6
WP_000135514.1\|1020355_1020814_-	phage virion morphogenesis protein	Q6QIB8	Burkholderia_phage	2.6e-30	44.8
WP_000117548.1\|1020816_1021638_-\|capsid	minor capsid protein	A4JWJ6	Burkholderia_virus	1.8e-98	61.9
WP_000090684.1\|1021618_1023115_-	DUF935 domain-containing protein	A4JWJ5	Burkholderia_virus	9.7e-167	59.0
WP_001295924.1\|1023114_1024647_-	hypothetical protein	A4JWJ4	Burkholderia_virus	6.2e-185	62.8
WP_000124060.1\|1024706_1025252_-	DUF3486 family protein	A4JWJ3	Burkholderia_virus	9.3e-59	67.6
1024787:1024802	attL	NA	NA	NA	NA
WP_000227701.1\|1025251_1025563_-	hypothetical protein	A0A0S4L0A3	Pseudomonas_phage	9.4e-32	62.6
WP_000175099.1\|1025562_1025889_-	hypothetical protein	Q6QIC4	Burkholderia_phage	1.1e-17	48.6
WP_000264665.1\|1025885_1026536_-	hypothetical protein	J9SVN7	Pseudomonas_phage	2.8e-09	32.9
WP_001104440.1\|1026519_1027260_-	transglycosylase SLT domain-containing protein	Q5ZQZ1	Pseudomonas_phage	2.5e-62	51.4
WP_000793146.1\|1027262_1027613_-	membrane protein	A4JWP3	Burkholderia_virus	1.5e-22	53.0
WP_000080195.1\|1027861_1029475_-\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000624722.1\|1029505_1029856_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000422741.1\|1029852_1030278_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000972294.1\|1031000_1031405_-	hypothetical protein	NA	NA	NA	NA
WP_001069611.1\|1031403_1031619_+	hypothetical protein	NA	NA	NA	NA
WP_000783854.1\|1031809_1032574_+	DNA adenine methylase	A2I2Y7	Vibrio_virus	5.2e-100	64.4
WP_000031013.1\|1032690_1033047_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000123378.1\|1033140_1033329_+	DNA-binding protein	Q5ZQZ9	Pseudomonas_phage	3.9e-17	71.0
WP_000047759.1\|1033381_1033690_+	helix-turn-helix domain-containing protein	Q5ZR02	Pseudomonas_phage	2.7e-23	55.9
WP_000533817.1\|1033700_1034621_+	DUF3102 domain-containing protein	A4JWN3	Burkholderia_virus	1.6e-74	56.2
WP_001095645.1\|1034620_1034938_+	hypothetical protein	NA	NA	NA	NA
WP_000186588.1\|1034953_1036723_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A4JWN2	Burkholderia_virus	1.5e-227	69.4
WP_000960679.1\|1036733_1037900_+	AAA family ATPase	A4JWN1	Burkholderia_virus	2.2e-121	59.4
WP_000843446.1\|1037902_1038172_+	hypothetical protein	NA	NA	NA	NA
WP_001140136.1\|1038199_1038730_+	host-nuclease inhibitor protein Gam	L7P7T1	Pseudomonas_phage	1.2e-58	66.7
WP_000632576.1\|1039018_1039291_+	hypothetical protein	NA	NA	NA	NA
WP_001295929.1\|1039300_1039597_+	hypothetical protein	NA	NA	NA	NA
WP_000763554.1\|1039611_1039827_+	hypothetical protein	NA	NA	NA	NA
WP_000132039.1\|1039823_1040507_+	DUF2786 domain-containing protein	A0A2P9JZH4	Alteromonadaceae_phage	1.1e-32	36.1
WP_000631813.1\|1040503_1040734_+	hypothetical protein	NA	NA	NA	NA
WP_000206212.1\|1040723_1040930_+	hypothetical protein	NA	NA	NA	NA
WP_001170114.1\|1040931_1041381_+	regulatory protein GemA	A4JWM5	Burkholderia_virus	6.1e-24	45.1
WP_001281701.1\|1041352_1041742_+	DNA-binding protein	Q6QIE8	Burkholderia_phage	1.5e-31	54.2
1046661:1046676	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1253068 : 1298777

Enterobacteria_phage(56.0%)

portal,head,terminase,tail,tRNA,integrase,holin,lysis,capsid

attL 1251386:1251400|attR 1279980:1279994

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1251386:1251400	attL	NA	NA	NA	NA
WP_001295972.1\|1253068_1254175_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000476093.1\|1254228_1254690_-	phosphatase NudJ	NA	NA	NA	NA
WP_001248677.1\|1254699_1255353_-	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_000444487.1\|1255524_1256775_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0
WP_000741335.1\|1256888_1258031_-\|integrase	tyrosine-type recombinase/integrase	Q77Z02	Phage_21	3.6e-206	100.0
WP_000088653.1\|1258020_1258257_-	excisionase	NA	NA	NA	NA
WP_000490213.1\|1258396_1258636_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	4.7e-39	96.2
WP_000002139.1\|1258619_1258946_-	ASCH domain-containing protein	A5VWB6	Enterobacteria_phage	9.8e-48	95.7
WP_000763374.1\|1258945_1259167_-	TraR/DksA family transcriptional regulator	A0A1I9LJM6	Stx_converting_phage	2.3e-32	93.2
WP_021533932.1\|1259265_1259547_-	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	3.0e-45	95.7
WP_000548516.1\|1259557_1259749_-	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	1.8e-25	93.7
WP_000149537.1\|1259721_1259904_-	DUF1317 domain-containing protein	A0A1U8QQC1	Enterobacteria_phage	1.8e-27	98.3
WP_000186848.1\|1259900_1260581_-	YqaJ viral recombinase family protein	A0A0P0ZCD4	Stx2-converting_phage	1.6e-132	100.0
WP_000100847.1\|1260577_1261363_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000995418.1\|1261368_1261665_-	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	8.9e-48	98.0
WP_000233576.1\|1261740_1261947_-	phage encoded cell division inhibitor protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
WP_000259990.1\|1262542_1263298_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	1.4e-92	75.0
WP_001067458.1\|1263336_1263567_+	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	1.5e-21	68.0
WP_001182900.1\|1263636_1264176_+	hypothetical protein	K7PJT7	Enterobacteria_phage	2.6e-61	67.0
WP_001435464.1\|1264262_1265192_+	replication protein	A0A0M5M7Y1	Salmonella_phage	6.1e-111	64.1
WP_000788794.1\|1265188_1265890_+	replication protein P of bacteriophage	M1FJ72	Enterobacteria_phage	1.5e-125	97.0
WP_022645049.1\|1266139_1270405_+	inverse autotransporter beta-barrel domain-containing protein	NA	NA	NA	NA
WP_000700202.1\|1270441_1271485_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_072147164.1\|1271834_1271936_+	hypothetical protein	NA	NA	NA	NA
WP_001053005.1\|1271932_1272388_+	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	1.6e-59	66.9
WP_000224914.1\|1272387_1272558_+	hypothetical protein	K7P7K0	Enterobacteria_phage	2.4e-13	69.8
WP_000774479.1\|1272550_1272841_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	2.3e-48	95.8
WP_001099488.1\|1272837_1273200_+	RusA family crossover junction endodeoxyribonuclease	K7PM48	Enterobacteria_phage	1.6e-59	95.7
WP_000971096.1\|1273196_1273337_+	YlcG family protein	K7PHH3	Enterobacteria_phage	8.5e-09	68.9
WP_001097224.1\|1273333_1274023_+	antiterminator Q	I6PDF8	Cronobacter_phage	4.9e-57	48.5
WP_000544528.1\|1274344_1274650_+\|holin	holin	A0A286N2Q5	Klebsiella_phage	7.0e-40	87.6
WP_001180486.1\|1274636_1275113_+	glycoside hydrolase family protein	K7PKV2	Enterobacteria_phage	7.3e-84	94.9
WP_001228695.1\|1275329_1275512_+\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	2.9e-17	98.3
WP_001298464.1\|1275602_1275896_-	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	7.0e-45	92.8
WP_000830178.1\|1276376_1276703_+	TonB family protein	H6WZK5	Escherichia_phage	3.7e-39	72.2
WP_000881610.1\|1276909_1277092_+	hypothetical protein	NA	NA	NA	NA
WP_000453620.1\|1277655_1278201_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	6.8e-94	98.3
WP_001027261.1\|1278175_1280101_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.1
1279980:1279994	attR	NA	NA	NA	NA
WP_000198149.1\|1280097_1280304_+\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_001295977.1\|1280300_1281902_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.4e-309	98.9
WP_000123268.1\|1281882_1283202_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.1e-230	97.7
WP_001295978.1\|1283211_1283544_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	3.8e-55	99.1
WP_000063293.1\|1283599_1284625_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	7.8e-192	99.4
WP_000158908.1\|1284666_1285065_+	DNA packaging protein from bacteriophage origin	A0A0K2FIR1	Enterobacteria_phage	1.0e-62	98.5
WP_000753018.1\|1285076_1285430_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	2.2e-61	98.3
WP_000985120.1\|1285441_1286020_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	92.7
WP_000683150.1\|1286016_1286412_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	2.9e-70	98.5
WP_001295979.1\|1286419_1287160_+\|tail	phage tail protein	A0A2I6TC77	Escherichia_phage	1.6e-130	98.0
WP_000479203.1\|1287175_1287598_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.2e-68	94.3
WP_000459457.1\|1287579_1288014_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_000840216.1\|1288006_1290568_+\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	98.4
WP_000847375.1\|1290564_1290894_+\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	2.8e-58	99.1
WP_001152626.1\|1290893_1291592_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	5.1e-134	99.6
WP_023146277.1\|1291596_1292340_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	5.0e-148	97.2
WP_023149564.1\|1292276_1292879_+\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.1e-88	85.6
WP_001531667.1\|1292939_1296422_+	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	90.3
WP_000290538.1\|1296480_1298502_+	hypothetical protein	A0A0E3M0V5	Enterobacteria_phage	7.2e-181	72.3
WP_000654172.1\|1298498_1298777_+	hypothetical protein	A0A0E3JSQ1	Enterobacteria_phage	9.9e-25	55.4

DBSCAN-SWA_3

1436738 : 1509844

Enterobacteria_phage(22.81%)

portal,head,terminase,protease,transposase,holin,integrase,capsid,tail

attL 1432912:1432926|attR 1438822:1438836

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1432912:1432926	attL	NA	NA	NA	NA
WP_000113700.1\|1436738_1437869_-\|integrase	tyrosine-type recombinase/integrase	O21940	Phage_21	3.4e-103	51.4
WP_000113189.1\|1437846_1438095_-	excisionase	NA	NA	NA	NA
WP_016230610.1\|1438159_1440631_-	exonuclease	A0A192Y6E0	Salmonella_phage	5.7e-55	56.0
1438822:1438836	attR	NA	NA	NA	NA
WP_001090200.1\|1440723_1440915_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449179.1\|1440911_1441100_-	hypothetical protein	NA	NA	NA	NA
WP_001171951.1\|1441665_1441884_-	hypothetical protein	NA	NA	NA	NA
WP_000379589.1\|1442043_1442199_-	DUF1391 family protein	M4QQ57	Salicola_phage	8.8e-07	51.1
WP_000103687.1\|1442471_1443188_-	helix-turn-helix domain-containing protein	H9C160	Pectobacterium_phage	1.7e-52	42.0
WP_000471549.1\|1443237_1443453_+	transcriptional regulator	NA	NA	NA	NA
WP_000693845.1\|1443449_1443875_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000095675.1\|1443897_1444860_+	DNA-binding protein	S5FM81	Shigella_phage	1.4e-70	56.4
WP_000788950.1\|1444866_1445613_+	ATP-binding protein	A0A088CBP4	Shigella_phage	4.0e-113	83.8
WP_000450998.1\|1445634_1446405_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.6e-80	64.5
WP_001151161.1\|1446420_1446846_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	2.2e-63	94.0
WP_000150294.1\|1447020_1447686_+	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_000018429.1\|1447866_1448079_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	5.2e-26	90.0
WP_001329966.1\|1448246_1448519_+	hypothetical protein	I6PCV7	Cronobacter_phage	5.5e-12	49.2
WP_001265085.1\|1448520_1449576_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.0e-90	48.4
WP_000140014.1\|1449576_1449957_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.9e-35	64.5
WP_001513213.1\|1449953_1450775_+	antitermination protein	K7P7B9	Enterobacteria_phage	1.7e-80	60.1
WP_000917751.1\|1451001_1451199_+	hypothetical protein	Q9MC00	Enterobacteria_phage	6.1e-29	98.5
WP_000024331.1\|1451350_1452400_+	site-specific DNA-methyltransferase	A0A0N7KZF8	Stx2-converting_phage	4.4e-198	95.4
WP_023142244.1\|1453201_1453333_+	DUF3927 family protein	H6WZJ7	Escherichia_phage	1.1e-05	100.0
WP_000871291.1\|1453613_1453949_-	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	5.2e-44	74.8
WP_016230612.1\|1454209_1456063_+	SASA family carbohydrate esterase	Q08JA2	Stx2-converting_phage	0.0e+00	90.3
WP_000284510.1\|1456213_1456429_+\|holin	holin	G9L6J5	Escherichia_phage	9.0e-34	100.0
WP_000193278.1\|1456433_1456778_+	YdfR family protein	K7PGU6	Enterobacteria_phage	2.8e-37	95.2
WP_000369850.1\|1456743_1457016_-	hypothetical protein	NA	NA	NA	NA
WP_000992071.1\|1457121_1457655_+	lysozyme	Q6H9V6	Enterobacteria_phage	4.8e-100	95.5
WP_032140280.1\|1458209_1458296_+	hypothetical protein	NA	NA	NA	NA
WP_012578895.1\|1458517_1458703_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	2.7e-18	98.4
WP_000736382.1\|1458788_1459004_+	hypothetical protein	NA	NA	NA	NA
WP_000095741.1\|1459202_1459403_-	YlcI/YnfO family protein	H6WZK6	Escherichia_phage	4.3e-30	98.5
WP_000829185.1\|1459444_1459810_+	HNH endonuclease	B6ETE5	Enterobacteria_phage	2.5e-60	93.4
WP_000958366.1\|1460100_1460664_+\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.6e-82	92.0
WP_001296023.1\|1460660_1462322_+\|terminase	terminase large subunit	B6DZ98	Enterobacteria_phage	0.0e+00	98.7
WP_000173031.1\|1462385_1464323_+\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	100.0
WP_001063099.1\|1464367_1464589_+	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_000267294.1\|1464534_1467120_+\|portal	phage portal protein	A0A0P0ZDD0	Stx2-converting_phage	0.0e+00	100.0
WP_000125990.1\|1467116_1467443_+\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZBH1	Stx2-converting_phage	9.2e-54	100.0
WP_001007905.1\|1467452_1467803_+\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000573391.1\|1467799_1468246_+	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_000133388.1\|1468242_1468587_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_001275441.1\|1468653_1469370_+\|tail	tail protein	A0A0P0ZDV1	Stx2-converting_phage	3.6e-127	99.6
WP_000710949.1\|1469384_1469759_+\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	1.7e-64	99.2
WP_123011843.1\|1469854_1470064_+	DUF4035 domain-containing protein	H6WZM0	Escherichia_phage	3.3e-33	98.6
WP_000608644.1\|1472323_1473586_+\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
WP_000239590.1\|1473841_1474717_+	class A extended-spectrum beta-lactamase CTX-M-15	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
WP_001393253.1\|1474763_1475096_-	cupin fold metalloprotein, WbuC family	NA	NA	NA	NA
WP_000807937.1\|1476592_1476934_+\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	9.0e-60	95.6
WP_001296027.1\|1476933_1477632_+\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	5.8e-130	97.4
WP_072048702.1\|1477924_1478524_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	6.7e-119	97.5
WP_061089814.1\|1478469_1479102_+\|tail	tail assembly protein	B6ETG3	Enterobacteria_phage	3.0e-101	97.6
WP_000514710.1\|1479444_1482918_+	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	89.7
WP_001298859.1\|1483558_1485100_+\|transposase	IS21-like element ISEc12 family transposase	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
WP_001016257.1\|1485114_1485861_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
WP_023363168.1\|1486329_1489155_+\|tail	tail protein	Q858V4	Yersinia_virus	9.0e-04	63.6
WP_000972097.1\|1489156_1489690_+\|tail	tail fiber assembly protein	A0A077SL44	Escherichia_phage	1.8e-67	70.1
WP_001164137.1\|1489720_1490248_-\|tail	tail fiber assembly protein	A0A0C4UR05	Shigella_phage	8.4e-73	77.7
WP_001513292.1\|1490263_1491232_-	hypothetical protein	A0A0F7LDR4	Escherichia_phage	6.5e-47	38.8
WP_001421220.1\|1491357_1491540_+	recombinase family protein	A0A0C4UR34	Shigella_phage	1.4e-24	95.0
WP_000240999.1\|1491738_1492407_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000937495.1\|1492463_1492733_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	9.3e-20	79.4
WP_001348267.1\|1493144_1493702_-	Rha family transcriptional regulator	Q8H9L9	Vibrio_phage	4.2e-30	63.8
WP_001296031.1\|1493698_1493974_-	hypothetical protein	S5MQL6	Escherichia_phage	1.1e-10	52.9
WP_000443082.1\|1494349_1495156_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_000209513.1\|1495155_1496349_-	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_001195273.1\|1496360_1497719_-	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	3.9e-37	41.2
WP_023149386.1\|1497722_1499318_-	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	3.8e-52	38.5
WP_001194644.1\|1499317_1500880_-	anthranilate synthase component I	NA	NA	NA	NA
WP_001700591.1\|1500971_1501016_-	trp operon leader peptide	NA	NA	NA	NA
WP_001285702.1\|1501153_1502035_+	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001295575.1\|1502031_1502652_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_001296033.1\|1502679_1504575_+	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_001291206.1\|1504787_1505663_+	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_023141019.1\|1505868_1506855_+	hypothetical protein	NA	NA	NA	NA
WP_001000715.1\|1506864_1507173_+	hypothetical protein	NA	NA	NA	NA
WP_001278898.1\|1507229_1507820_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_000559273.1\|1507816_1508575_-	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	4.4e-06	23.4
WP_000422062.1\|1508794_1509844_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5

DBSCAN-SWA_4

2001013 : 2089259

103

Escherichia_phage(22.73%)

portal,terminase,holin,plate,transposase,tRNA,integrase,capsid,tail

attL 2046710:2046769|attR 2089321:2089445

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099156422.1\|2001013_2002362_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.7e-74	52.4
WP_000568520.1\|2002471_2003482_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	5.6e-09	25.5
WP_000580323.1\|2003490_2004102_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_072093883.1\|2004240_2004306_-	hypothetical protein	NA	NA	NA	NA
WP_001024911.1\|2004376_2004979_+	YebB family permuted papain-like enzyme	NA	NA	NA	NA
WP_001295503.1\|2004980_2005502_-	crossover junction endodeoxyribonuclease RuvC	G3MA90	Bacillus_virus	2.0e-10	35.1
WP_000907234.1\|2005536_2006277_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_077249130.1\|2006305_2006758_-	dihydroneopterin triphosphate diphosphatase	NA	NA	NA	NA
WP_001258676.1\|2006750_2008523_-\|tRNA	aspartate--tRNA ligase	NA	NA	NA	NA
WP_000891625.1\|2008832_2009399_+	hydrolase	NA	NA	NA	NA
WP_000639277.1\|2009395_2010214_+	DUF72 domain-containing protein	Q859D1	Escherichia_coli_phage	6.5e-72	99.2
WP_000252980.1\|2010266_2010662_+	hypothetical protein	NA	NA	NA	NA
WP_000019588.1\|2010702_2011446_+	carboxy-S-adenosyl-L-methionine synthase CmoA	F5B419	Synechococcus_phage	4.6e-24	30.0
WP_000564759.1\|2011442_2012414_+\|tRNA	tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB	NA	NA	NA	NA
WP_000176764.1\|2012449_2014879_-	trimethylamine N-oxide reductase TorZ	NA	NA	NA	NA
WP_001214293.1\|2014903_2016004_-	cytochrome c	NA	NA	NA	NA
WP_001185734.1\|2016391_2017138_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_001490174.1\|2017151_2017718_-	VOC family protein	NA	NA	NA	NA
WP_001025326.1\|2017933_2019667_+\|tRNA	arginine--tRNA ligase	A0A2K9L6Z2	Tupanvirus	8.8e-87	33.7
WP_001202076.1\|2019719_2020112_-	flagellar protein FlhE	NA	NA	NA	NA
WP_000066973.1\|2020111_2022190_-	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_001278946.1\|2022182_2023331_-	flagellar type III secretion system protein FlhB	NA	NA	NA	NA
WP_000983600.1\|2023519_2024164_-	protein phosphatase CheZ	NA	NA	NA	NA
WP_000763867.1\|2024174_2024564_-	chemotaxis protein CheY	A0A2K9L4R0	Tupanvirus	1.3e-06	32.0
WP_000036371.1\|2024578_2025628_-	protein-glutamate methylesterase/protein glutamine deamidase	Q56AR1	Bacillus_thuringiensis_phage	1.0e-05	32.8
WP_000204320.1\|2025630_2026491_-	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_001296146.1\|2026781_2028443_-	methyl-accepting chemotaxis protein II	A0A2H4J162	uncultured_Caudovirales_phage	1.7e-10	40.3
WP_000147302.1\|2028587_2029091_-	chemotaxis protein CheW	NA	NA	NA	NA
WP_001531763.1\|2029111_2031076_-	chemotaxis protein CheA	NA	NA	NA	NA
WP_000795641.1\|2031080_2032007_-	flagellar motor protein MotB	NA	NA	NA	NA
WP_000906342.1\|2032003_2032891_-	flagellar motor stator protein MotA	NA	NA	NA	NA
WP_001291603.1\|2033017_2033596_-	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
WP_001295647.1\|2033598_2033949_-	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
WP_000122413.1\|2034728_2035157_+	universal stress protein UspC	NA	NA	NA	NA
WP_001296148.1\|2035163_2036588_-	alpha,alpha-trehalose-phosphate synthase	NA	NA	NA	NA
WP_001296149.1\|2036562_2037363_-	trehalose-phosphatase	NA	NA	NA	NA
WP_000987895.1\|2037529_2038519_-	arabinose ABC transporter permease AraH	NA	NA	NA	NA
WP_001187827.1\|2038530_2040045_-	arabinose ABC transporter ATP binding protein AraG	A0A285PWH2	Cedratvirus	1.3e-12	29.7
WP_000548680.1\|2040114_2041104_-	arabinose ABC transporter substrate-binding protein AraF	NA	NA	NA	NA
WP_000179469.1\|2041898_2042402_+	non-heme ferritin-like protein	NA	NA	NA	NA
WP_000082127.1\|2042479_2042731_-	DUF2766 domain-containing protein	NA	NA	NA	NA
WP_010723106.1\|2042845_2042932_-	stress response protein AzuC	NA	NA	NA	NA
WP_001237881.1\|2043195_2043519_+	hypothetical protein	NA	NA	NA	NA
WP_000917208.1\|2043690_2044188_+	non-heme ferritin	NA	NA	NA	NA
WP_000377224.1\|2044225_2044465_-	YecH family protein	NA	NA	NA	NA
WP_000797555.1\|2044655_2045867_+	tyrosine transporter TyrP	NA	NA	NA	NA
WP_000847882.1\|2045917_2046583_-	UPF0149 family protein YecA	NA	NA	NA	NA
2046710:2046769	attL	NA	NA	NA	NA
WP_001296152.1\|2047054_2047474_-	hypothetical protein	G8C7Q7	Escherichia_phage	1.8e-49	68.8
WP_001531767.1\|2048688_2048913_-	hypothetical protein	NA	NA	NA	NA
WP_001531768.1\|2049074_2049464_-\|tail	phage tail protein	E5FFG4	Burkholderia_phage	1.0e-14	37.9
WP_001018353.1\|2049499_2051140_-	hypothetical protein	A0A2I7R3J9	Vibrio_phage	1.2e-19	29.3
WP_000444667.1\|2051248_2051530_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_000785563.1\|2051542_2052055_-\|tail	phage tail protein	NA	NA	NA	NA
WP_000117510.1\|2052072_2053575_-\|tail	tail sheath protein	R9TMQ0	Vibrio_phage	5.5e-69	33.5
WP_000626358.1\|2053571_2053961_-	hypothetical protein	A0A2H4EXG4	Aeromonas_phage	9.4e-05	30.8
WP_000829621.1\|2053960_2055145_-\|tail	phage tail protein	J9QDX3	Clostridium_phage	2.5e-16	35.2
WP_000203868.1\|2055137_2055764_-\|tail	phage tail protein I	A0A193GYD1	Enterobacter_phage	2.0e-25	38.8
WP_000633314.1\|2055766_2056687_-\|plate	baseplate assembly protein	D5LGZ3	Escherichia_phage	6.4e-68	47.8
WP_000901289.1\|2056683_2057025_-\|plate	phage baseplate assembly protein	D4HTV2	Vibrio_phage	1.1e-20	51.6
WP_000079174.1\|2057027_2057930_-\|plate	phage baseplate assembly protein V	NA	NA	NA	NA
WP_000015612.1\|2057910_2058447_-	hypothetical protein	NA	NA	NA	NA
WP_000774516.1\|2058443_2059124_-	hypothetical protein	NA	NA	NA	NA
WP_001531773.1\|2059155_2059536_-	hypothetical protein	NA	NA	NA	NA
WP_000105179.1\|2059532_2059952_-	DNA-packaging protein	NA	NA	NA	NA
WP_001283997.1\|2059986_2061021_-\|capsid	major capsid protein	A0A2I6TCE5	Escherichia_phage	6.6e-106	56.5
WP_000206292.1\|2061079_2061409_-	hypothetical protein	A0A2R9YJN3	Escherichia_phage	2.0e-08	39.5
WP_001145892.1\|2061408_2062716_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	4.9e-106	53.7
WP_000126513.1\|2062715_2064290_-\|portal	phage portal protein	E4WL21	Enterobacteria_phage	8.6e-190	64.0
WP_000203897.1\|2064286_2064520_-	hypothetical protein	NA	NA	NA	NA
WP_000148195.1\|2064519_2066382_-\|terminase	phage terminase large subunit family protein	A0A1I9KF19	Aeromonas_phage	1.1e-191	53.2
WP_000168117.1\|2066368_2066935_-	hypothetical protein	A0A1I9KFT4	Aeromonas_phage	2.9e-31	46.2
WP_001531775.1\|2067303_2067549_+	hypothetical protein	NA	NA	NA	NA
WP_000734931.1\|2067608_2067803_-	hypothetical protein	NA	NA	NA	NA
WP_000131873.1\|2067810_2068290_-	TIGR02594 family protein	A0A222YWL8	Escherichia_phage	4.6e-62	68.8
WP_000172496.1\|2068289_2068562_-\|holin	phage holin family protein	A0A0A0YPY6	Escherichia_phage	9.8e-09	42.9
WP_001294589.1\|2068561_2068945_-	hypothetical protein	NA	NA	NA	NA
WP_000064384.1\|2069057_2069729_-	antitermination protein	Q7Y3X2	Yersinia_phage	1.9e-16	33.5
WP_000717783.1\|2069728_2070022_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	3.3e-34	70.5
WP_000057010.1\|2070018_2070615_-	DUF1367 family protein	H9C173	Pectobacterium_phage	1.5e-70	64.1
WP_001025459.1\|2070692_2070872_-	hypothetical protein	NA	NA	NA	NA
WP_000847617.1\|2071023_2071665_-	hypothetical protein	NA	NA	NA	NA
WP_000536919.1\|2071908_2072142_+	hypothetical protein	NA	NA	NA	NA
WP_000224749.1\|2072540_2073029_+	ImmA/IrrE family metallo-endopeptidase	A0A142KB62	Gordonia_phage	6.4e-27	42.7
WP_001138663.1\|2073038_2073644_+	hypothetical protein	NA	NA	NA	NA
WP_000536231.1\|2074106_2074805_-	hypothetical protein	Q858R8	Enterobacteria_phage	1.5e-117	91.4
WP_001237642.1\|2075992_2076916_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_001531776.1\|2077090_2077879_-	ORF6N domain-containing protein	A0A0P0ZC44	Stx2-converting_phage	1.1e-39	69.8
WP_000661082.1\|2078560_2078785_-	hypothetical protein	NA	NA	NA	NA
WP_000875806.1\|2078781_2079093_-	hypothetical protein	A0A222YXX1	Escherichia_phage	1.2e-34	65.7
WP_000918616.1\|2079089_2079326_-	hypothetical protein	NA	NA	NA	NA
WP_000214056.1\|2079327_2079738_-	hypothetical protein	NA	NA	NA	NA
WP_000609322.1\|2079776_2081192_-	AAA family ATPase	H9C165	Pectobacterium_phage	6.6e-173	66.7
WP_001023813.1\|2081181_2081937_-	hypothetical protein	H9C164	Pectobacterium_phage	2.4e-41	68.5
WP_000943914.1\|2081933_2082158_-	hypothetical protein	H9C163	Pectobacterium_phage	6.1e-17	54.1
WP_000431205.1\|2082197_2082674_-	hypothetical protein	H9C162	Pectobacterium_phage	1.9e-23	48.6
WP_000360804.1\|2082732_2082963_-	transcriptional regulator	H6WRX5	Salmonella_phage	1.5e-21	63.2
WP_001296165.1\|2083061_2083475_+	helix-turn-helix domain-containing protein	A0A1B5FPF4	Escherichia_phage	8.7e-09	49.1
WP_000388260.1\|2084485_2084806_+	hypothetical protein	NA	NA	NA	NA
WP_000151806.1\|2084836_2087053_+	hypothetical protein	H9C157	Pectobacterium_phage	4.7e-101	35.6
WP_000100753.1\|2087049_2087619_+	siphovirus Gp157 family protein	H9C156	Pectobacterium_phage	6.1e-37	49.2
WP_000916334.1\|2087618_2087801_+	hypothetical protein	NA	NA	NA	NA
WP_000833838.1\|2088010_2088274_+	DUF4224 domain-containing protein	H9C153	Pectobacterium_phage	1.2e-06	38.0
WP_001531780.1\|2088242_2089259_+\|integrase	tyrosine-type recombinase/integrase	H9C152	Pectobacterium_phage	1.1e-126	63.6
2089321:2089445	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2107503 : 2185636

Escherichia_phage(40.0%)

portal,head,terminase,protease,transposase,holin,integrase,capsid,tail

attL 2142279:2142294|attR 2208638:2208653

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001347174.1\|2107503_2108028_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.2e-33	60.0
WP_000879824.1\|2108184_2108982_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001310919.1\|2108991_2109543_-	Raf kinase inhibitor-like protein YbcL	NA	NA	NA	NA
WP_001070440.1\|2109711_2110044_-	SMR family multidrug efflux protein EmrE	NA	NA	NA	NA
WP_001274299.1\|2110387_2110702_-	flagellar hook-basal body complex protein FliE	NA	NA	NA	NA
WP_000994425.1\|2110916_2112575_+	flagellar basal body M-ring protein FliF	NA	NA	NA	NA
WP_000067950.1\|2112567_2113563_+	flagellar motor switch protein FliG	NA	NA	NA	NA
WP_001282677.1\|2113555_2114242_+	flagellar assembly protein FliH	NA	NA	NA	NA
WP_000213308.1\|2114241_2115615_+	flagellum-specific ATP synthase FliI	NA	NA	NA	NA
WP_000807584.1\|2115633_2116077_+	flagella biosynthesis chaperone FliJ	NA	NA	NA	NA
WP_000620069.1\|2116073_2117201_+	flagellar hook length control protein FliK	NA	NA	NA	NA
WP_000133106.1\|2117305_2117770_+	flagellar basal body-associated protein FliL	NA	NA	NA	NA
WP_001295641.1\|2117774_2118779_+	flagellar motor switch protein FliM	NA	NA	NA	NA
WP_001282103.1\|2118775_2119189_+	flagellar motor switch protein FliN	NA	NA	NA	NA
WP_001313947.1\|2119191_2119557_+	flagellar type III secretion system protein FliO	NA	NA	NA	NA
WP_001253318.1\|2119556_2120294_+	flagellar type III secretion system pore protein FliP	NA	NA	NA	NA
WP_000187358.1\|2120303_2120573_+	flagellar biosynthesis protein FliQ	NA	NA	NA	NA
WP_000983988.1\|2120581_2121367_+	flagellar type III secretion system protein FliR	NA	NA	NA	NA
WP_000103992.1\|2121656_2122280_+	transcriptional regulator RcsA	NA	NA	NA	NA
WP_071524607.1\|2122323_2122566_-	protein DsrB	NA	NA	NA	NA
WP_000844800.1\|2122674_2122902_+	peroxide/acid resistance protein YodD	NA	NA	NA	NA
WP_000491527.1\|2123197_2124013_+	mannosyl-3-phosphoglycerate phosphatase-related protein	NA	NA	NA	NA
WP_001531784.1\|2124009_2125704_-	cellulose biosynthesis regulator YedQ	A0A127AWB9	Bacillus_phage	1.3e-18	35.6
WP_000009307.1\|2125874_2126057_-	DUF2158 domain-containing protein	NA	NA	NA	NA
WP_000922683.1\|2126135_2127053_-	DUF808 domain-containing protein	NA	NA	NA	NA
WP_001212226.1\|2127225_2128146_+	drug/metabolite exporter YedA	NA	NA	NA	NA
WP_000228686.1\|2128134_2128605_-	VSPR family DNA mismatch endonuclease	E5E3X5	Burkholderia_phage	5.2e-34	48.3
WP_001157265.1\|2128585_2130004_-	DNA-cytosine methyltransferase	E5E3X6	Burkholderia_phage	1.0e-101	55.1
WP_001296176.1\|2130070_2130766_-	phosphohydrolase	S4W232	Pandoravirus	1.6e-07	28.7
WP_001330593.1\|2130805_2131171_-	hypothetical protein	NA	NA	NA	NA
WP_000824383.1\|2131736_2132852_+	outer membrane protein F	Q1MVN1	Enterobacteria_phage	2.9e-91	47.4
WP_000218217.1\|2133444_2134296_+	protein deglycase HchA	NA	NA	NA	NA
WP_000826711.1\|2134403_2135762_-	two-component system sensor histidine kinase HprS	NA	NA	NA	NA
WP_001347103.1\|2135761_2136433_-	response regulator transcription factor HprR	W8CYM9	Bacillus_phage	5.4e-32	35.2
WP_000920127.1\|2136565_2136979_+	hydroxyisourate hydrolase	NA	NA	NA	NA
WP_000740067.1\|2137087_2138092_+	protein-methionine-sulfoxide reductase catalytic subunit MsrP	NA	NA	NA	NA
WP_001240063.1\|2138092_2138728_+	protein-methionine-sulfoxide reductase heme-binding subunit MsrQ	NA	NA	NA	NA
WP_102776447.1\|2138811_2140160_-\|transposase	IS3-like element IS1397 family transposase	A0A1B1P773	Bacillus_phage	5.1e-74	52.4
WP_001007778.1\|2140420_2141071_+	metal-binding protein ZinT	NA	NA	NA	NA
WP_000355363.1\|2142154_2142442_-	hypothetical protein	NA	NA	NA	NA
2142279:2142294	attL	NA	NA	NA	NA
WP_000235978.1\|2142452_2143157_-\|tail	tail fiber domain-containing protein	A0A1X7QGH6	Escherichia_phage	4.6e-58	61.7
WP_000654141.1\|2143166_2143448_-	hypothetical protein	A0A1X7QHA1	Escherichia_phage	1.6e-17	47.8
WP_001554173.1\|2143447_2145826_-\|tail	phage tail fiber protein	A0A1X7QGG5	Escherichia_phage	1.9e-185	76.1
WP_000526135.1\|2145946_2146405_-\|transposase	IS200/IS605 family transposase	I4AZI8	Saccharomonospora_phage	2.9e-13	32.3
WP_001228252.1\|2146601_2147201_-	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	3.4e-102	92.5
WP_001554175.1\|2147268_2150664_-	host specificity protein J	A0A0K2FI38	Escherichia_phage	0.0e+00	88.6
WP_000741570.1\|2150724_2151372_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	6.6e-112	97.2
WP_000140743.1\|2151269_2152013_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	4.1e-150	97.6
WP_001152448.1\|2152018_2152717_-\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	3.8e-129	94.8
WP_001330090.1\|2152716_2153073_-\|tail	tail protein	A0A0P0ZDL9	Stx2-converting_phage	2.8e-40	66.7
WP_000224009.1\|2153050_2156278_-\|tail	phage tail tape measure protein	A0A1B5FPE2	Escherichia_phage	0.0e+00	95.7
WP_071590020.1\|2156324_2156585_-	DUF4035 domain-containing protein	A0A1B5FP87	Escherichia_phage	1.6e-40	97.7
WP_001324129.1\|2156626_2157013_-\|tail	tail assembly protein	A0A1B5FP91	Escherichia_phage	8.9e-64	100.0
WP_000097526.1\|2157012_2157717_-	immunoglobulin domain-containing protein	A0A1B5FP82	Escherichia_phage	3.7e-116	94.4
WP_001206306.1\|2157777_2158122_-	DUF3168 domain-containing protein	A0A1B5FP84	Escherichia_phage	1.4e-55	97.4
WP_014639219.1\|2158118_2158568_-	HK97 gp10 family phage protein	S4TR46	Salmonella_phage	1.0e-63	80.5
WP_001147814.1\|2158564_2158903_-\|head	phage head closure protein	A0A1B5FP90	Escherichia_phage	7.5e-51	90.2
WP_000719066.1\|2158911_2159229_-\|head,tail	phage gp6-like head-tail connector protein	A0A1W6JNZ5	Morganella_phage	6.2e-23	50.5
WP_000766111.1\|2159305_2160523_-\|capsid	phage major capsid protein	A0A1W6JP20	Morganella_phage	4.5e-162	71.6
WP_000999828.1\|2160537_2161137_-\|head,protease	HK97 family phage prohead protease	Q8SBH9	Shigella_phage	1.9e-89	81.0
WP_000923132.1\|2161129_2162356_-\|portal	phage portal protein	Q8SBI0	Shigella_phage	1.5e-202	82.6
WP_001140907.1\|2162503_2164261_-\|terminase	terminase large subunit	A0A1B5FP96	Escherichia_phage	0.0e+00	98.9
WP_001554177.1\|2164260_2164743_-\|terminase	phage terminase small subunit P27 family	A0A1B5FPA0	Escherichia_phage	7.4e-84	96.9
WP_001135103.1\|2164890_2165241_-	HNH endonuclease	A0A1B5FP94	Escherichia_phage	4.7e-64	97.4
WP_000738421.1\|2165766_2166060_+	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	5.9e-44	90.7
WP_075202333.1\|2166150_2166333_-	hypothetical protein	A0A0P0ZE50	Stx2-converting_phage	2.2e-17	77.0
WP_000992101.1\|2166549_2167083_-	lysozyme	Q08J98	Stx2-converting_phage	1.1e-99	93.8
WP_000193269.1\|2167146_2167497_-	YdfR family protein	K7PGU6	Enterobacteria_phage	1.9e-36	94.0
WP_000372595.1\|2167501_2167717_-\|holin	holin	A0A2R2Z340	Escherichia_phage	3.4e-33	98.6
WP_000874243.1\|2168024_2168213_-	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	7.2e-27	95.2
WP_000871291.1\|2168472_2168808_+	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	5.2e-44	74.8
WP_000562553.1\|2169088_2169220_-	DUF3927 family protein	H6WZJ7	Escherichia_phage	3.7e-06	100.0
WP_021538919.1\|2170115_2170937_-	antitermination protein	K7P7B9	Enterobacteria_phage	1.5e-76	58.2
WP_000139998.1\|2170951_2171314_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	9.6e-36	63.6
WP_001296186.1\|2171314_2172373_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	7.5e-89	47.7
WP_023141427.1\|2172374_2172647_-	hypothetical protein	I6PCV7	Cronobacter_phage	4.2e-12	50.8
WP_000813254.1\|2172814_2172970_-	type I toxin-antitoxin system toxin HokD	A0A0U2QV81	Escherichia_phage	1.5e-17	96.1
WP_011076332.1\|2173228_2173447_-	hypothetical protein	NA	NA	NA	NA
WP_001224667.1\|2174060_2174243_-	hypothetical protein	A0A2R2Z308	Escherichia_phage	2.0e-26	96.7
WP_000761442.1\|2174336_2174750_-	hypothetical protein	A0A2R2Z307	Escherichia_phage	4.6e-58	98.3
WP_001151210.1\|2174750_2175173_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.3e-63	90.6
WP_000095675.1\|2175213_2176176_-	DNA-binding protein	S5FM81	Shigella_phage	1.4e-70	56.4
WP_000693943.1\|2176198_2176624_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000391951.1\|2176607_2176889_-	hypothetical protein	K7PHA1	Enterobacteria_phage	6.5e-24	72.6
WP_000362153.1\|2176989_2177409_+	hypothetical protein	K7PK07	Enterobacteria_phage	8.8e-25	65.1
WP_000379575.1\|2177674_2177830_+	DUF1391 family protein	M4QQ57	Salicola_phage	3.0e-07	53.2
WP_001171947.1\|2177989_2178208_+	hypothetical protein	NA	NA	NA	NA
WP_001296188.1\|2178211_2178376_-	hypothetical protein	NA	NA	NA	NA
WP_000854558.1\|2178775_2178964_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001070254.1\|2178960_2179152_+	DUF1482 family protein	NA	NA	NA	NA
WP_023363203.1\|2179244_2181716_+	exonuclease	K7PLW7	Enterobacteria_phage	3.8e-59	60.9
WP_000096342.1\|2181774_2181978_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_000533615.1\|2181977_2183003_+\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	3.4e-102	57.9
WP_001311896.1\|2183238_2184036_+	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_000060157.1\|2184373_2185636_+\|integrase	tyrosine-type recombinase/integrase	A0A1B0VMI6	Pseudomonas_phage	2.6e-72	38.5
2208638:2208653	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2252525 : 2286286

Escherichia_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001296203.1\|2252525_2253722_+\|transposase	IS110-like element ISEc20 family transposase	NA	NA	NA	NA
WP_001304240.1\|2253845_2254124_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_000813432.1\|2254217_2254820_+	hypothetical protein	NA	NA	NA	NA
WP_000970353.1\|2255845_2256538_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	1.7e-118	88.4
WP_000255956.1\|2256537_2257560_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.0e-199	99.1
WP_089438313.1\|2257705_2257885_+\|transposase	transposase	NA	NA	NA	NA
WP_001296206.1\|2259084_2260230_+	hypothetical protein	NA	NA	NA	NA
WP_001163787.1\|2260760_2261018_-	hypothetical protein	NA	NA	NA	NA
WP_000016207.1\|2261071_2261839_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.5e-14	27.9
WP_000217077.1\|2261835_2262894_-	iron ABC transporter permease	NA	NA	NA	NA
WP_000778018.1\|2262912_2263902_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000856948.1\|2263912_2266078_-	TonB-dependent receptor	NA	NA	NA	NA
WP_001069649.1\|2266506_2266941_+	hypothetical protein	NA	NA	NA	NA
WP_001531797.1\|2267158_2269543_+	hypothetical protein	NA	NA	NA	NA
WP_000203551.1\|2269539_2270445_+	chemotaxis protein	NA	NA	NA	NA
WP_000102633.1\|2270441_2271512_+	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_001542273.1\|2271647_2272061_+	hypothetical protein	NA	NA	NA	NA
WP_001298859.1\|2272175_2273717_+\|transposase	IS21-like element ISEc12 family transposase	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
WP_001016257.1\|2273731_2274478_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
WP_000846703.1\|2274926_2275337_+	hypothetical protein	NA	NA	NA	NA
WP_001542275.1\|2275557_2276376_+	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	8.8e-45	38.6
WP_001542276.1\|2276717_2277191_+	antirestriction protein	A0A2D0W9W4	Bordetella_phage	4.3e-12	33.1
WP_001186200.1\|2277206_2277683_+	RadC family protein	NA	NA	NA	NA
WP_000692345.1\|2277745_2277967_+	DUF987 domain-containing protein	A0A142F0X9	Klebsiella_phage	1.9e-10	45.8
WP_000086752.1\|2277985_2278630_+	hypothetical protein	A0A2I6PI07	Pseudomonas_phage	1.8e-24	32.9
WP_001280918.1\|2278645_2279014_+	type IV toxin-antitoxin system YeeU family antitoxin	NA	NA	NA	NA
WP_000854815.1\|2279102_2279477_+	type IV toxin-antitoxin system toxin CbtA	NA	NA	NA	NA
WP_000988600.1\|2279473_2279668_+	hypothetical protein	NA	NA	NA	NA
WP_001161660.1\|2279680_2279794_+	DUF957 domain-containing protein	NA	NA	NA	NA
WP_032082634.1\|2280082_2280256_-\|transposase	transposase	A0A0P0ZBS5	Stx2-converting_phage	1.1e-10	54.2
WP_001296208.1\|2280282_2280465_+	hypothetical protein	NA	NA	NA	NA
WP_000450409.1\|2280565_2280895_-	DUF496 family protein	NA	NA	NA	NA
WP_001200889.1\|2281066_2282125_-	FUSC family protein	NA	NA	NA	NA
WP_001105368.1\|2282322_2282796_-	DNA gyrase inhibitor SbmC	NA	NA	NA	NA
WP_001296209.1\|2282914_2284081_-	serine-type D-Ala-D-Ala carboxypeptidase DacD	B6DZZ7	Stx2-converting_phage	5.9e-228	99.5
WP_000980556.1\|2284289_2285717_+	exodeoxyribonuclease I	NA	NA	NA	NA
WP_023363206.1\|2285827_2286286_-\|transposase	IS200/IS605 family transposase	I4AZI8	Saccharomonospora_phage	3.2e-12	31.5

DBSCAN-SWA_7

2309433 : 2315736

Enterobacteria_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001100793.1\|2309433_2309976_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	6.0e-50	61.8
WP_000857525.1\|2309980_2310859_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	6.6e-107	64.5
WP_001023641.1\|2310916_2311816_-	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	1.7e-28	34.8
WP_000699407.1\|2311815_2312901_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	8.8e-101	53.9
WP_000183040.1\|2313273_2314167_-	UTP--glucose-1-phosphate uridylyltransferase GalF	A0A127AW70	Bacillus_phage	3.0e-46	42.0
WP_001116066.1\|2314341_2315736_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	6.3e-19	33.0

DBSCAN-SWA_8

2409912 : 2419357

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001292786.1\|2409912_2411049_+	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	6.1e-161	96.7
WP_001296230.1\|2411045_2413049_+	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.7
WP_001296231.1\|2413173_2413635_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	3.2e-76	99.3
WP_001295430.1\|2413675_2414146_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_000598641.1\|2414192_2414912_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001295431.1\|2414908_2416594_-	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_001240408.1\|2416815_2417547_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	6.3e-111	98.5
WP_001216963.1\|2417606_2417714_+	protein YohO	NA	NA	NA	NA
WP_000783109.1\|2417694_2418426_-	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_000569347.1\|2418430_2419357_-	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	1.3e-23	30.8

DBSCAN-SWA_9

2657135 : 2669500

Enterobacteria_phage(44.44%)

transposase,integrase

attL 2656957:2656976|attR 2671085:2671104

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2656957:2656976	attL	NA	NA	NA	NA
WP_000926944.1\|2657135_2658311_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	2.8e-145	63.0
WP_000287253.1\|2658290_2659241_-	sce7725 family protein	NA	NA	NA	NA
WP_000019149.1\|2659262_2660144_-	sce7726 family protein	NA	NA	NA	NA
WP_000080195.1\|2660697_2662311_-\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000624722.1\|2662341_2662692_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000422741.1\|2662688_2663114_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000239754.1\|2663451_2663688_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	9.0e-19	66.7
WP_000783295.1\|2663942_2664215_-	ogr/Delta-like zinc finger family protein	F1BUM8	Cronobacter_phage	3.2e-20	50.0
WP_000856856.1\|2664497_2667185_-	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	4.2e-112	35.0
WP_001063904.1\|2667181_2667592_-	hypothetical protein	NA	NA	NA	NA
WP_000839713.1\|2667584_2667821_-	hypothetical protein	NA	NA	NA	NA
WP_001111085.1\|2667817_2668408_-	ash family protein	Q7M2A7	Enterobacteria_phage	4.4e-22	49.2
WP_000270796.1\|2668495_2669500_-	oxidoreductase	F1BUM2	Cronobacter_phage	1.1e-81	48.3
2671085:2671104	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2886860 : 2976065

Enterobacteria_phage(52.54%)

portal,lysis,terminase,protease,tRNA,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000083664.1\|2886860_2887598_-\|tRNA	tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase TrmN	NA	NA	NA	NA
WP_000219193.1\|2887729_2889064_+	ATP-dependent RNA helicase SrmB	E3T5E1	Cafeteria_roenbergensis_virus	2.9e-45	30.8
WP_001296304.1\|2889096_2889978_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000189207.1\|2890080_2890668_+	cysteine/O-acetylserine transporter	NA	NA	NA	NA
WP_000627804.1\|2890723_2891107_-	autonomous glycyl radical cofactor GrcA	A0A088FS37	Shigella_phage	4.7e-33	70.9
WP_001262723.1\|2891411_2892101_+	uracil-DNA glycosylase	A0A077BCN4	Equid_alphaherpesvirus	2.1e-55	52.1
WP_000997384.1\|2892148_2893186_-\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
WP_001098726.1\|2893392_2893812_+	thioredoxin TrxC	A0A0K2FIM3	Achromobacter_phage	2.8e-15	38.5
WP_001296305.1\|2893880_2894579_+	DTW domain-containing protein	NA	NA	NA	NA
WP_000082935.1\|2894610_2897271_+	protein lysine acetyltransferase	NA	NA	NA	NA
WP_001312028.1\|2897384_2898740_+	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_001467872.1\|2898785_2899109_+	YfiM family lipoprotein	NA	NA	NA	NA
WP_000852119.1\|2899105_2900404_-	alpha-ketoglutarate permease	Q6JIH2	Burkholderia_virus	2.4e-44	31.5
WP_001235102.1\|2906190_2908764_-	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	2.6e-127	35.3
WP_000040156.1\|2908893_2909625_-	polyphenol oxidase	NA	NA	NA	NA
WP_000079111.1\|2909621_2910602_-	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_000197686.1\|2910736_2911474_+	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_000178456.1\|2911743_2912085_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_001386991.1\|2912188_2912236_+	hypothetical protein	NA	NA	NA	NA
WP_000200140.1\|2912334_2913495_+	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_000225212.1\|2913537_2914659_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_001168045.1\|2914669_2915740_-	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	4.0e-90	51.2
WP_001296308.1\|2915949_2916315_+	DUF2799 domain-containing protein	NA	NA	NA	NA
WP_001212400.1\|2916461_2916980_+	YfiR family protein	NA	NA	NA	NA
WP_000969008.1\|2916969_2918196_+	diguanylate cyclase DgcN	NA	NA	NA	NA
WP_000589791.1\|2918211_2918694_+	OmpA family protein	NA	NA	NA	NA
WP_000065253.1\|2918770_2919118_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_000264790.1\|2919159_2919927_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_000043335.1\|2919957_2920506_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_000256450.1\|2920524_2920773_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_000460035.1\|2920909_2922271_-	signal recognition particle protein	NA	NA	NA	NA
WP_001189256.1\|2922362_2923229_+	inner membrane protein YpjD	NA	NA	NA	NA
WP_010723175.1\|2923249_2924536_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001296310.1\|2924589_2925183_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_001059176.1\|2925305_2926184_+	NAD(+) kinase	NA	NA	NA	NA
WP_000880939.1\|2926269_2927931_+	DNA repair protein RecN	NA	NA	NA	NA
WP_001203437.1\|2928079_2928421_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_001117834.1\|2928482_2928773_-	RnfH family protein	NA	NA	NA	NA
WP_000600193.1\|2928762_2929239_-	type II toxin-antitoxin system toxin RatA	NA	NA	NA	NA
WP_000162574.1\|2929370_2929853_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
WP_000429347.1\|2930730_2931000_+	hypothetical protein	NA	NA	NA	NA
WP_000461705.1\|2931137_2931500_-	type II toxin-antitoxin system RnlB family antitoxin	NA	NA	NA	NA
WP_024190590.1\|2931492_2932563_-	type II toxin-antitoxin system RnlA family toxin	NA	NA	NA	NA
WP_001597763.1\|2932622_2932778_-	hypothetical protein	A0A1S6L009	Salmonella_phage	2.2e-05	92.6
WP_023363231.1\|2932963_2933548_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	5.0e-103	95.4
WP_023363234.1\|2933547_2936574_-\|tail	tail protein	U5N099	Enterobacteria_phage	6.1e-67	80.7
WP_023363237.1\|2936638_2937238_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	1.7e-109	97.5
WP_023363240.1\|2937304_2940703_-	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	89.4
WP_125271823.1\|2940763_2941372_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	4.8e-104	97.0
WP_023363246.1\|2941308_2942052_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.5e-147	96.8
WP_023363250.1\|2942056_2942755_-\|tail	phage minor tail protein L	A5LH40	Enterobacteria_phage	6.8e-131	97.0
WP_000447253.1\|2942764_2943094_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	1.7e-60	100.0
WP_023363253.1\|2943093_2946159_-\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	0.0e+00	98.7
WP_032164532.1\|2946130_2946460_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	2.9e-55	99.1
WP_001300035.1\|2946468_2946855_-\|tail	phage minor tail protein G	A0A291AWW5	Escherichia_phage	1.6e-65	100.0
WP_000211106.1\|2946915_2947659_-\|tail	tail protein	K7PGT7	Enterobacteria_phage	1.6e-133	100.0
WP_023363259.1\|2947669_2948071_-\|tail	tail protein	A5LH34	Enterobacteria_phage	5.4e-72	98.5
WP_000677106.1\|2948067_2948646_-\|tail	phage tail protein	A5LH33	Enterobacteria_phage	4.2e-102	100.0
WP_023363262.1\|2948657_2948933_-	DNA breaking-rejoining protein	K7PH43	Enterobacteria_phage	5.0e-45	98.9
WP_001097045.1\|2948925_2949249_-	DUF2190 family protein	K7PLV6	Enterobacteria_phage	8.5e-52	100.0
WP_023363265.1\|2949336_2951364_-\|protease	Clp protease ClpP	K7PGT6	Enterobacteria_phage	0.0e+00	99.2
WP_023363268.1\|2951308_2952817_-\|portal	phage portal protein	K7PJP3	Enterobacteria_phage	1.9e-287	99.2
WP_001072975.1\|2952816_2953029_-	hypothetical protein	A5LH28	Enterobacteria_phage	1.1e-31	100.0
WP_023363271.1\|2953025_2955128_-\|terminase	phage terminase large subunit family protein	K7PH40	Enterobacteria_phage	0.0e+00	99.7
WP_023363274.1\|2955127_2955622_-	DUF1441 family protein	A0A291AWV8	Escherichia_phage	4.9e-83	99.4
WP_001139681.1\|2956297_2956450_-	hypothetical protein	K7PKL2	Enterobacteria_phage	4.7e-21	96.0
WP_001300226.1\|2956437_2956905_-\|lysis	lysis protein	K7PH77	Enterobacteria_phage	2.9e-77	100.0
WP_000992100.1\|2956901_2957435_-	lysozyme	Q08J98	Stx2-converting_phage	3.6e-100	94.4
WP_000193288.1\|2957498_2957849_-	YdfR family protein	K7PGU6	Enterobacteria_phage	1.9e-36	94.0
WP_000839596.1\|2957853_2958069_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_000799656.1\|2958136_2959189_-	site-specific DNA-methyltransferase	A5LH81	Enterobacteria_phage	2.7e-208	100.0
WP_000917724.1\|2959339_2959543_-	hypothetical protein	A0A291AWX6	Escherichia_phage	6.1e-32	100.0
WP_000217632.1\|2959766_2960192_-	hypothetical protein	A0A291AWZ9	Escherichia_phage	3.6e-74	100.0
WP_001547994.1\|2960472_2961225_-	antitermination protein	K7PGU5	Enterobacteria_phage	2.8e-138	100.0
WP_001439745.1\|2961238_2962228_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	9.5e-195	99.4
WP_015967850.1\|2962235_2963045_-	KilA-N domain-containing protein	Q8SBE6	Shigella_phage	6.0e-155	100.0
WP_000767124.1\|2963064_2963454_-	RusA family crossover junction endodeoxyribonuclease	Q8SBE7	Shigella_phage	7.1e-69	100.0
WP_023363277.1\|2963450_2963777_-	LexA family transcriptional regulator	A5LH73	Enterobacteria_phage	3.5e-53	99.1
WP_000066917.1\|2963773_2964427_-	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	1.9e-127	99.5
WP_023363280.1\|2964426_2964915_-	PerC family transcriptional regulator	A0A0P0ZCF0	Stx2-converting_phage	2.0e-84	97.5
WP_000061525.1\|2964917_2965736_-	helix-turn-helix domain-containing protein	Q8SBF1	Shigella_phage	1.2e-121	99.6
WP_000620696.1\|2965732_2965957_-	hypothetical protein	A5LH70	Enterobacteria_phage	5.7e-39	100.0
WP_001087357.1\|2965953_2967105_-	peptidase	A0A0P0ZE80	Stx2-converting_phage	1.1e-210	97.4
WP_000515841.1\|2967101_2967653_-	hypothetical protein	K7PGU3	Enterobacteria_phage	4.9e-100	98.4
WP_023363283.1\|2967645_2967906_-	helix-turn-helix transcriptional regulator	K7PJQ8	Enterobacteria_phage	6.0e-40	98.8
WP_001311077.1\|2968003_2968696_+	helix-turn-helix transcriptional regulator	S5FUZ3	Shigella_phage	2.9e-121	96.5
WP_000135680.1\|2969418_2969781_+	hypothetical protein	Q8SBF8	Shigella_phage	8.6e-61	100.0
WP_023277820.1\|2969846_2970671_+	DUF2303 family protein	U5P439	Shigella_phage	4.3e-148	99.3
WP_023363286.1\|2970799_2971336_+	5'-deoxynucleotidase	U5P0T3	Shigella_phage	4.1e-99	98.9
WP_001596853.1\|2971326_2971689_+	hypothetical protein	K7PH61	Enterobacteria_phage	1.5e-65	97.5
WP_001331173.1\|2971685_2971901_+	hypothetical protein	K7PLX1	Enterobacteria_phage	1.2e-14	65.1
WP_001331174.1\|2971960_2972167_+	hypothetical protein	I6PBM8	Cronobacter_phage	6.9e-23	70.3
WP_001596854.1\|2972127_2973294_+	DUF3596 domain-containing protein	I6PDJ1	Cronobacter_phage	1.8e-147	67.2
WP_001596855.1\|2973352_2975086_+	ATP-binding protein	NA	NA	NA	NA
WP_023363292.1\|2975165_2976065_+	DNA adenine methylase	A0A0C5AMX6	Cyanophage	2.5e-08	23.2

DBSCAN-SWA_11

3044776 : 3051916

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000103863.1\|3044776_3047338_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.6e-31	20.8
WP_001141293.1\|3047443_3048100_+	protein-serine/threonine phosphatase	A0A077SLQ6	Escherichia_phage	3.3e-50	46.1
WP_001272542.1\|3048150_3048948_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	2.2e-69	57.0
WP_000847996.1\|3049113_3050022_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	1.9e-117	76.2
WP_000590411.1\|3050018_3051281_+	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	2.2e-135	61.4
WP_001279004.1\|3051277_3051916_+	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	74.5

DBSCAN-SWA_12

3303724 : 3365814

Staphylococcus_phage(33.33%)

tRNA,transposase,integrase,protease

attL 3304933:3304950|attR 3365211:3365228

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001296354.1\|3303724_3304483_+\|protease	metalloprotease LoiP	NA	NA	NA	NA
WP_000105562.1\|3304912_3305833_-	agmatinase	NA	NA	NA	NA
3304933:3304950	attL	NA	NA	NA	NA
WP_000758881.1\|3305968_3306700_-	hypothetical protein	NA	NA	NA	NA
WP_001295380.1\|3306845_3308822_-	biosynthetic arginine decarboxylase	NA	NA	NA	NA
WP_001297406.1\|3308830_3308962_-	acid stress response protein YqgB	NA	NA	NA	NA
WP_001331575.1\|3309097_3309313_+	hypothetical protein	NA	NA	NA	NA
WP_001062128.1\|3309616_3310771_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.0e-128	63.2
WP_001112301.1\|3311206_3312601_+	galactose/proton symporter	NA	NA	NA	NA
WP_001296359.1\|3312677_3313175_+\|protease	SprT family zinc-dependent metalloprotease	NA	NA	NA	NA
WP_000286500.1\|3313269_3313977_+	deoxyribonuclease I	NA	NA	NA	NA
WP_001222509.1\|3314056_3314788_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_000593274.1\|3314800_3315751_+	glutathione synthase	NA	NA	NA	NA
WP_000126441.1\|3315787_3316423_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_000017111.1\|3316422_3316839_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_001296360.1\|3316953_3317934_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_000997795.1\|3317951_3318656_+	pyridoxal phosphate homeostasis protein	NA	NA	NA	NA
WP_001094831.1\|3318673_3319240_+	osmotic shock tolerance protein YggT	NA	NA	NA	NA
WP_001277229.1\|3319236_3319527_+	YggU family protein	NA	NA	NA	NA
WP_001174754.1\|3319534_3320128_+	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_000239963.1\|3320120_3321257_+	radical SAM family heme chaperone HemW	NA	NA	NA	NA
WP_000783999.1\|3321571_3322558_+	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_000577034.1\|3322602_3323106_+	TRAP transporter small permease	NA	NA	NA	NA
WP_000378955.1\|3323105_3324407_+	TRAP transporter large permease subunit	NA	NA	NA	NA
WP_000745240.1\|3324462_3325470_-	DUF1202 family protein	NA	NA	NA	NA
WP_000394132.1\|3325586_3326633_-	L-asparaginase 2	NA	NA	NA	NA
WP_000984796.1\|3326808_3327528_-	DUF2884 domain-containing protein	NA	NA	NA	NA
WP_001296361.1\|3327548_3327689_-	hypothetical protein	NA	NA	NA	NA
WP_001107566.1\|3327711_3328038_-	YggL family protein	NA	NA	NA	NA
WP_000786911.1\|3328037_3328757_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_001296362.1\|3328917_3329970_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_000091700.1\|3329997_3330273_+	oxidative damage protection protein	NA	NA	NA	NA
WP_000760323.1\|3330337_3331417_+	membrane-bound lytic murein transglycosylase MltC	NA	NA	NA	NA
WP_001296363.1\|3331618_3332875_+	nucleoside permease NupG	NA	NA	NA	NA
WP_000839781.1\|3332923_3335059_-	ornithine decarboxylase	NA	NA	NA	NA
WP_000234526.1\|3335451_3336159_+	DUF554 domain-containing protein	NA	NA	NA	NA
WP_001218869.1\|3336537_3337803_+\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	2.1e-77	38.1
WP_000147017.1\|3338058_3339102_+	hypothetical protein	NA	NA	NA	NA
WP_001774069.1\|3340795_3341347_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000006213.1\|3343838_3344072_+	Major pilus subunit operon regulatory protein	NA	NA	NA	NA
WP_023146305.1\|3344538_3344754_+	hypothetical protein	A0A0N7C1Y0	Escherichia_phage	1.7e-27	85.2
WP_099156432.1\|3344722_3345849_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	2.5e-146	96.6
WP_001513409.1\|3345939_3346053_-	hypothetical protein	NA	NA	NA	NA
WP_001110186.1\|3347886_3348147_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_000109147.1\|3348188_3348749_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_001296373.1\|3348788_3349217_+	DUF417 family protein	NA	NA	NA	NA
WP_000074472.1\|3349934_3351128_-	MFS transporter	NA	NA	NA	NA
WP_001296374.1\|3351263_3352988_+	aerobactin synthase IucA	NA	NA	NA	NA
WP_001287500.1\|3352988_3353936_+	N(6)-hydroxylysine O-acetyltransferase	NA	NA	NA	NA
WP_001015715.1\|3353935_3355678_+	aerobactin synthase IucC	NA	NA	NA	NA
WP_000750130.1\|3355674_3356952_+	NADPH-dependent L-lysine N(6)-monooxygenase	NA	NA	NA	NA
WP_000973516.1\|3357033_3359235_+	ferric aerobactin receptor IutA	NA	NA	NA	NA
WP_001034083.1\|3360178_3364066_+\|protease	serine protease autotransporter toxin Sat	Q9LA58	Enterobacterial_phage	1.2e-227	39.0
WP_001254932.1\|3364662_3365814_+\|transposase	IS30-like element IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-42	35.6
3365211:3365228	attR	NA	NA	NA	NA

DBSCAN-SWA_13

4906087 : 4963463

Stx2-converting_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000080195.1\|4906087_4907701_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000107487.1\|4907971_4908985_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_000998348.1\|4908996_4910313_-	L-fucose:H+ symporter permease	NA	NA	NA	NA
WP_000350265.1\|4910340_4911261_-	ribokinase	NA	NA	NA	NA
WP_001295538.1\|4911566_4912349_+	DeoR family transcriptional regulator	NA	NA	NA	NA
WP_001387298.1\|4912350_4912449_-	acetolactate synthase	NA	NA	NA	NA
WP_000527665.1\|4913574_4913682_+	alcohol dehydrogenase	NA	NA	NA	NA
WP_000145475.1\|4913862_4914519_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_001296707.1\|4914766_4916044_-	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_001545177.1\|4916106_4918104_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	4.4e-21	25.9
WP_000336726.1\|4918258_4919077_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.2e-65	45.2
WP_000088391.1\|4919112_4919415_-\|transposase	transposase	NA	NA	NA	NA
WP_000177057.1\|4920348_4920606_+	hypothetical protein	NA	NA	NA	NA
WP_000175457.1\|4921162_4921930_-	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	6.4e-13	24.8
WP_000684856.1\|4921930_4922887_-	Fe(3+) dicitrate ABC transporter permease subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	26.1
WP_000125187.1\|4922883_4923882_-	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
WP_000879164.1\|4923878_4924781_-	Fe(3+) dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
WP_000188262.1\|4924825_4927150_-	Fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
WP_001068908.1\|4927236_4928190_-	fec operon regulator FecR	NA	NA	NA	NA
WP_001283626.1\|4928186_4928708_-	RNA polymerase sigma factor FecI	NA	NA	NA	NA
WP_000823243.1\|4930269_4931628_+	esterase-like activity of phytase family protein	NA	NA	NA	NA
WP_000998019.1\|4931866_4933252_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	3.4e-259	89.3
WP_000612591.1\|4933301_4933649_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171523.1\|4933645_4934026_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
WP_001221615.1\|4934380_4934815_-	hypothetical protein	NA	NA	NA	NA
WP_000270962.1\|4934802_4935204_-	hypothetical protein	NA	NA	NA	NA
WP_000221530.1\|4935463_4936033_-	inovirus Gp2 family protein	NA	NA	NA	NA
WP_001547002.1\|4936232_4936430_+	hypothetical protein	NA	NA	NA	NA
WP_071526287.1\|4936762_4936912_-	hemolysin activation protein	NA	NA	NA	NA
WP_000211308.1\|4937685_4937892_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000813435.1\|4937987_4938590_+	hypothetical protein	NA	NA	NA	NA
WP_000250227.1\|4939790_4940708_+	hypothetical protein	NA	NA	NA	NA
WP_001553935.1\|4940792_4941665_+	GTPase family protein	NA	NA	NA	NA
WP_021526504.1\|4942037_4944884_+	autotransporter adhesin Ag43	NA	NA	NA	NA
WP_001323397.1\|4944954_4945113_+	DUF905 family protein	NA	NA	NA	NA
WP_001234738.1\|4945267_4946086_+	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	9.4e-47	39.7
WP_001350782.1\|4946427_4946901_+	antirestriction protein	A9J566	Pseudomonas_phage	8.7e-13	30.3
WP_001186775.1\|4946916_4947393_+	RadC family protein	NA	NA	NA	NA
WP_000692345.1\|4947455_4947677_+	DUF987 domain-containing protein	A0A142F0X9	Klebsiella_phage	1.9e-10	45.8
WP_001295723.1\|4947839_4948208_+	antitoxin	NA	NA	NA	NA
WP_000854759.1\|4948297_4948675_+	toxin	NA	NA	NA	NA
WP_000761690.1\|4948671_4949160_+	hypothetical protein	NA	NA	NA	NA
WP_000839286.1\|4949176_4949353_+	DUF957 domain-containing protein	NA	NA	NA	NA
WP_144079987.1\|4949458_4949656_+	hypothetical protein	NA	NA	NA	NA
WP_000422741.1\|4949670_4950096_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000624722.1\|4950092_4950443_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000080195.1\|4950473_4952087_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000107487.1\|4952357_4953371_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_000998348.1\|4953382_4954699_-	L-fucose:H+ symporter permease	NA	NA	NA	NA
WP_000350265.1\|4954726_4955647_-	ribokinase	NA	NA	NA	NA
WP_001295538.1\|4955952_4956735_+	DeoR family transcriptional regulator	NA	NA	NA	NA
WP_001387298.1\|4956736_4956835_-	acetolactate synthase	NA	NA	NA	NA
WP_000527665.1\|4957960_4958068_+	alcohol dehydrogenase	NA	NA	NA	NA
WP_000145475.1\|4958248_4958905_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_001296707.1\|4959152_4960430_-	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_001545177.1\|4960492_4962490_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	4.4e-21	25.9
WP_000336726.1\|4962644_4963463_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.2e-65	45.2

DBSCAN-SWA_14

4989653 : 4996473

Stx2-converting_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001234738.1\|4989653_4990472_+	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	9.4e-47	39.7
WP_001350782.1\|4990813_4991287_+	antirestriction protein	A9J566	Pseudomonas_phage	8.7e-13	30.3
WP_001186775.1\|4991302_4991779_+	RadC family protein	NA	NA	NA	NA
WP_000692345.1\|4991841_4992063_+	DUF987 domain-containing protein	A0A142F0X9	Klebsiella_phage	1.9e-10	45.8
WP_001295723.1\|4992225_4992594_+	antitoxin	NA	NA	NA	NA
WP_000854759.1\|4992683_4993061_+	toxin	NA	NA	NA	NA
WP_000761690.1\|4993057_4993546_+	hypothetical protein	NA	NA	NA	NA
WP_000839286.1\|4993562_4993739_+	DUF957 domain-containing protein	NA	NA	NA	NA
WP_144079987.1\|4993844_4994042_+	hypothetical protein	NA	NA	NA	NA
WP_000422741.1\|4994056_4994482_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000624722.1\|4994478_4994829_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000080195.1\|4994859_4996473_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_022651

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

30 : 48598

Macacine_betaherpesvirus(19.05%)

transposase,integrase,protease

attL 5086:5100|attR 30618:30632

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000080195.1\|30_1644_-\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000624722.1\|1674_2025_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000422741.1\|2021_2447_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_031325939.1\|2508_3660_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_000151784.1\|3693_4206_-	hypothetical protein	NA	NA	NA	NA
WP_000813634.1\|4751_4970_+	type II toxin-antitoxin system antitoxin CcdA	NA	NA	NA	NA
WP_001159868.1\|4971_5277_+	type II toxin-antitoxin system toxin CcdB	NA	NA	NA	NA
5086:5100	attL	NA	NA	NA	NA
WP_000016982.1\|5277_6084_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	5.8e-57	100.0
WP_000852146.1\|6857_7613_+	replication initiation protein RepE	I3WF20	Macacine_betaherpesvirus	3.8e-143	100.0
WP_000772446.1\|8200_9367_+	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	7.0e-229	100.0
WP_000817036.1\|9366_10338_+	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	7.0e-174	99.4
WP_106426161.1\|11135_12077_+	DUF1281 domain-containing protein	NA	NA	NA	NA
WP_000086185.1\|12490_13174_+	DNA methylase	A0A2I7RE86	Vibrio_phage	5.1e-30	36.9
WP_001104873.1\|13174_13396_+	hypothetical protein	NA	NA	NA	NA
WP_000274437.1\|13409_13844_+	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_001671341.1\|15210_15513_+	antirestriction protein	NA	NA	NA	NA
WP_000271753.1\|15559_15982_+	DUF1380 family protein	NA	NA	NA	NA
WP_001027516.1\|15978_16170_+	hypothetical protein	NA	NA	NA	NA
WP_000218642.1\|17198_17429_+	hypothetical protein	NA	NA	NA	NA
WP_000170728.1\|17480_18842_+	DUF3560 domain-containing protein	NA	NA	NA	NA
WP_012783964.1\|18888_19452_+	class I SAM-dependent methyltransferase	A8HNV9	Thalassomonas_phage	4.7e-21	37.3
WP_032140903.1\|19896_20088_+	hypothetical protein	NA	NA	NA	NA
WP_000290793.1\|20315_20843_+	single-stranded DNA-binding protein	I3PGW4	Xanthomonas_phage	6.7e-46	54.3
WP_000006004.1\|20898_21132_+	DUF905 domain-containing protein	A0A096XUX0	Cronobacter_phage	3.9e-06	51.1
WP_001145469.1\|21190_23149_+	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	4.7e-20	29.2
WP_000845901.1\|23203_23638_+	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_001276234.1\|23634_24354_+	plasmid SOS inhibition protein A	NA	NA	NA	NA
WP_001299721.1\|24365_24554_-	hypothetical protein	NA	NA	NA	NA
WP_001312861.1\|24633_24792_+	type I toxin-antitoxin system Hok family toxin	NA	NA	NA	NA
WP_001067855.1\|25142_25847_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000616807.1\|27893_28547_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000557619.1\|28639_28897_+	type II toxin-antitoxin system antitoxin PemI	NA	NA	NA	NA
WP_001398199.1\|28829_29231_+	type II toxin-antitoxin system toxin endoribonuclease PemK	NA	NA	NA	NA
WP_001067855.1\|31249_31954_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
30618:30632	attR	NA	NA	NA	NA
WP_001334766.1\|32585_33416_-	oxacillin-hydrolyzing class D beta-lactamase OXA-1	NA	NA	NA	NA
WP_063840321.1\|33546_34101_-	fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5	NA	NA	NA	NA
WP_001067855.1\|34244_34949_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001235713.1\|35218_35776_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_000027057.1\|35958_36819_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_000130647.1\|37844_38702_-	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_001365705.1\|38694_38769_-	RepA leader peptide Tap	NA	NA	NA	NA
WP_000083819.1\|38993_39254_-	replication regulatory protein RepA	NA	NA	NA	NA
WP_000766805.1\|39493_40084_-	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_001298565.1\|40121_40331_-	hemolysin expression modulator Hha	NA	NA	NA	NA
WP_001233838.1\|40376_40838_-	thermonuclease family protein	A0A0R6PHV6	Moraxella_phage	4.2e-20	37.1
WP_001309245.1\|41082_41295_-	ANR family transcriptional regulator	NA	NA	NA	NA
WP_000139321.1\|41423_41984_-	fertility inhibition protein FinO	NA	NA	NA	NA
WP_000704523.1\|42086_42947_-	alpha/beta hydrolase	A2RQC8	Archaeal_BJ1_virus	1.9e-10	23.5
WP_000205725.1\|43005_43752_-	type-F conjugative transfer system pilin acetylase TraX	A0A077JBM8	Xanthomonas_phage	2.4e-09	30.8
WP_001067855.1\|47893_48598_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022648

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_022651

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection