CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022997	Hyphomicrobium nitrativorans NL23, complete sequence	11 crisprs	DEDDh,csa3,cas2,cas1,cas4,cas7b,cas8c,cas5,cas3	5	27	2	0

1. NC_022997

CRISPR-Cas detection and classification

Crispr_ID: NC_022997_1

• CRISPR_ID: NC_022997_1
• CRISPR_location: 224988-225074
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_022997_1

Consensus_repeat	Method
TGATAGGGCCTGAAGCGATCATGGTCTC	CRISPRCasFinder

spacers of NC_022997_1

>1.1|225016|31|NC_022997|CRISPRCasFinder
TTTTGTCAGACCGATGATTCACGCTTCAGGG

CRISPR arrays and Neighbor proteins around NC_022997_1

CRISPR arrays

The CRISPR arrays of NC_022997_1

>merge|NC_022997|1|224988-225074|CRISPRCasFinder
TGATAGGGCCTGAAGCGATCATGGTCTCTTTTGTCAGACCGATGATTCACGCTTCAGGGTGATAGGGCCTGAAGCGATCATGGTCTC

>NC_022997|1|1|224988-225074|CRISPRCasFinder
TGATAGGGCCTGAAGCGATCATGGTCTC	TTTTGTCAGACCGATGATTCACGCTTCAGGG
TGATAGGGCCTGAAGCGATCATGGTCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_041316103.1|227352_228879_-|histidine--tRNA-ligase	unknown	unknown	gnl|CDD|234586
NC_022997.1|WP_023785648.1|220372_221905_-|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NC_022997.1|WP_023785656.1|229029_230244_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl|CDD|223890
NC_022997.1|WP_081717793.1|234517_234787_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023785654.1|225138_225849_-|ATP-phosphoribosyltransferase	unknown	unknown	gnl|CDD|237438
NC_022997.1|WP_041316899.1|224297_224528_+|DUF1150-domain-containing-protein	unknown	unknown	gnl|CDD|369004
NC_022997.1|WP_023785644.1|216424_218146_+|iron-ABC-transporter-permease	unknown	unknown	gnl|CDD|224099
NC_022997.1|WP_023785650.1|222688_223447_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023785647.1|219615_219930_-|hypothetical-protein	unknown	unknown	gnl|CDD|367272
NC_022997.1|WP_144083469.1|231963_232776_-|hypothetical-protein	unknown	unknown	gnl|CDD|236138
NC_022997.1|WP_023785655.1|225845_227024_-|ATP-phosphoribosyltransferase-regulatory-subunit	unknown	unknown	gnl|CDD|183413
NC_022997.1|WP_023785646.1|218817_219369_-|cytochrome-b	unknown	unknown	gnl|CDD|225580
NC_022997.1|WP_023785645.1|218200_218776_-|YceI-family-protein	unknown	unknown	gnl|CDD|179642
NC_022997.1|WP_023785662.1|233008_234244_+|argininosuccinate-synthase	unknown	unknown	gnl|CDD|234785
NC_022997.1|WP_023785649.1|222057_222453_+|VOC-family-protein	unknown	unknown	gnl|CDD|319965
NC_022997.1|WP_023785658.1|230775_231207_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023785651.1|223625_224057_+|Hsp20-family-protein	unknown	unknown	gnl|CDD|107227
NC_022997.1|WP_144083468.1|230252_230675_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023785653.1|224612_224885_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023785659.1|231308_231908_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_041316103.1|227352_228879_-|histidine--tRNA-ligase	gnl|CDD|234586	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed.	2.19888e-142
NC_022997.1|WP_023785648.1|220372_221905_-|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NC_022997.1|WP_023785656.1|229029_230244_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl|CDD|223890	COG0820, COG0820, Predicted Fe-S-cluster redox enzyme [General function prediction only].	5.13862e-175
NC_022997.1|WP_023785654.1|225138_225849_-|ATP-phosphoribosyltransferase	gnl|CDD|237438	PRK13583, hisG, ATP phosphoribosyltransferase.	7.45353e-105
NC_022997.1|WP_041316899.1|224297_224528_+|DUF1150-domain-containing-protein	gnl|CDD|369004	pfam06620, DUF1150, Protein of unknown function (DUF1150). This family consists of several hypothetical bacterial proteins of unknown function.	2.71179e-31
NC_022997.1|WP_023785644.1|216424_218146_+|iron-ABC-transporter-permease	gnl|CDD|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	2.64694e-95
NC_022997.1|WP_023785647.1|219615_219930_-|hypothetical-protein	gnl|CDD|367272	pfam02956, TT_ORF1, TT viral orf 1. TT virus (TTV), isolated initially from a Japanese patient with hepatitis of unknown aetiology, has since been found to infect both healthy and diseased individuals and numerous prevalence studies have raised questions about its role in unexplained hepatitis. ORF1 is a large 750 residue protein. The N-terminal half of this protein corresponds to the capsid protein.	0.000167207
NC_022997.1|WP_023785655.1|225845_227024_-|ATP-phosphoribosyltransferase-regulatory-subunit	gnl|CDD|183413	PRK12295, hisZ, ATP phosphoribosyltransferase regulatory subunit; Provisional.	3.46892e-109
NC_022997.1|WP_023785646.1|218817_219369_-|cytochrome-b	gnl|CDD|225580	COG3038, CybB, Cytochrome B561 [Energy production and conversion].	1.11942e-47
NC_022997.1|WP_023785645.1|218200_218776_-|YceI-family-protein	gnl|CDD|179642	PRK03757, PRK03757, YceI family protein.	2.16326e-110
NC_022997.1|WP_023785662.1|233008_234244_+|argininosuccinate-synthase	gnl|CDD|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NC_022997.1|WP_023785649.1|222057_222453_+|VOC-family-protein	gnl|CDD|319965	cd16358, GlxI_Ni, Glyoxalase I that uses Ni(++) as cofactor. This family includes Escherichia coil and other prokaryotic glyoxalase I that uses nickel as cofactor. Glyoxalase I (also known as lactoylglutathione lyase; EC 4.4.1.5) is part of the glyoxalase system, a two-step system for detoxifying methylglyoxal, a side product of glycolysis. This system is responsible for the conversion of reactive, acyclic alpha-oxoaldehydes into the corresponding alpha-hydroxyacids and involves 2 enzymes, glyoxalase I and II. Glyoxalase I catalyses an intramolecular redox reaction of the hemithioacetal (formed from methylglyoxal and glutathione) to form the thioester, S-D-lactoylglutathione. This reaction involves the transfer of two hydrogen atoms from C1 to C2 of the methylglyoxal, and proceeds via an ene-diol intermediate. Glyoxalase I has a requirement for bound metal ions for catalysis. Eukaryotic glyoxalase I prefers the divalent cation zinc as cofactor, whereas Escherichia coil and other prokaryotic glyoxalase I uses nickel. However, eukaryotic Trypanosomatid parasites also use nickel as a cofactor, which could possibly be explained by acquiring their GLOI gene by horizontal gene transfer. Human glyoxalase I is a two-domain enzyme and it has the structure of a domain-swapped dimer with two active sites located at the dimer interface. In yeast, in various plants, insects and Plasmodia, glyoxalase I is four-domain, possibly the result of a further gene duplication and an additional gene fusing event.	2.40745e-22
NC_022997.1|WP_023785651.1|223625_224057_+|Hsp20-family-protein	gnl|CDD|107227	cd06470, ACD_IbpA-B_like, Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins. IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. IbpA and IbpB are produced during high-level production of various heterologous proteins, specifically human prorenin, renin and bovine insulin-like growth factor 2 (bIGF-2), and are strongly associated with inclusion bodies containing these heterologous proteins. IbpA and IbpB work as an integrated system to stabilize thermally aggregated proteins in a disaggregation competent state. The chaperone activity of IbpB is also significantly elevated as the temperature increases from normal to heat shock. The high temperature results in the disassociation of 2-3-MDa IbpB oligomers into smaller approximately 600-kDa structures. This elevated activity seen under heat shock conditions is retained for an extended period of time after the temperature is returned to normal. IbpA also forms multimers.	7.28068e-38
NC_022997.1|WP_144083469.1|231963_232776_-|hypothetical-protein	gnl|CDD|236138	PRK07994, PRK07994, DNA polymerase III subunits gamma and tau; Validated.	1.51034e-10

Protein sequences

>NC_022997.1|WP_023785653.1|224612_224885_+|hypothetical-protein
MSLAGVERLLTLLQLYTPLIGSDAATPVDVTLEVRGPFVAGEAAGPLLVLLLLLDRKLAVHLAIGLSRRVAGSSTRRENGSGTASHEKTP
>NC_022997.1|WP_041316899.1|224297_224528_+|DUF1150-domain-containing-protein
MSDIELARLGGGQVAYIKTLSSDEALQMFPAIEDLPRGIHLYALHAADGTPIALTDTRQAALSHAMDGELEIASVH
>NC_022997.1|WP_023785651.1|223625_224057_+|Hsp20-family-protein
MSRLSVLSNPFLLGFEEIERLIDRTGKGGGEGYPPYNIERVAAHDGDKEKLRITIALAGFTRDQLEIVVEDNQLIVRGRQADDKSRTYLYRGIATRQFTRTFVLADGIEVKAAELSNGLLIIDLVRHEPDKLVRRIEIGTGGG
>NC_022997.1|WP_023785650.1|222688_223447_+|hypothetical-protein
MPAASEVADPAQHFVPEPASSPDPIPAAFVCRHTGAPCPALASLFASLNPTGPEAREWVQALAPCGFCRVAFEAERDRLRRLRLGQREREILLGAARAGVLVLTERGMARSLSASRRRAAQSLGKAGLVTPASATPNGRSTRAAVTLTDLGRYVMAAYGRFLEGQKPVRWTRPAAGVELPGCDPALLRDEALARTHTALRTTLDDLKGVLVAAIAGRAKDPDVLDRMSRHLEQKATLLKAVLEPLRTRPARG
>NC_022997.1|WP_023785649.1|222057_222453_+|VOC-family-protein
MAKAIHMMVRVLNEERSVAFYSGAFGLEIADRYDFADFTLVYLRNAETDFELELTVNKGRKDPYELGNGYGHFAVAVEDLEETRARIAELGYFPKDIKQMIFEDKPFGRFFFIEDPDGYKIEVLEKGGRFR
>NC_022997.1|WP_023785648.1|220372_221905_-|acyl-CoA-carboxylase-subunit-beta
MKEVIEELERRRDNARLGGGIQRIEAQHKRGKLTARERIELLMDENSFEEFDTFVEHRCADFGMEKSKTPGDGVVTGWGTINGRVVYVFAKDFTVFGGSLSQAHAQKIMKIQDMALKNRAPIIGVFDAGGARIQEGVDALGGYGEVFQRNVLASGVIPQISVIMGPCAGGDVYSPAMTDFIFMVKDTSYMFVTGPDVVKTVTNETVTAEELGGAKVHTTKSSIADRAYENDVEALLQMRRLMDFLPSNNQSGVPVLPTSDSPDRPDYSLDTLIPDNPNKPYDIKELILKVVDEADFFEIQEAYARNIVTGFARMEGRTIGIVANQPMVLAGVLDSDASRKAARFVRFCDCFEIPIVTFVDVPGFLPGTAQEYGGLIKHGAKLLFAYAEATVPKVTLITRKAYGGAYDVMSSKHIRGDVNYAWPTAEIAVMGAKGAAEILYRSELSDPAKIQVRIDEYQRRFANPFVAAERGYIDEVILPHGTRRRICRALNMLRNKTLENPWKKHDNIPL
>NC_022997.1|WP_023785647.1|219615_219930_-|hypothetical-protein
MRKLIAVAMLGAGAAFFAAAPAQAMPASGAAGIASKLATTDNAGVHEVRRRYYRHRHRGYRRGWRHRGYYGHRRHYRPRYYYGGPGYYGYRYHRRPRLGIYFGL
>NC_022997.1|WP_023785646.1|218817_219369_-|cytochrome-b
MLMRDTTSGYGLVSRLFHWITALVIFGLFGLGVWMVGLGYYDPLYHTAPHWHKSVGMLFAFALVARFAWRIANVKPSDDDLAPAERIAARIAHWSFYVLLFAIVVTGYLMSTADGRPIHVFDWFAIPSPGANPGLESTAGAVHVWLSYAVIALAAVHTLAALKHHVHDRKPTLTRMWSGPPRV
>NC_022997.1|WP_023785645.1|218200_218776_-|YceI-family-protein
MLHRLSPLALVAALVVATPASAADYAIDTKGAHASINFRVNHLGFSWLTGRFDTFGGTFSYDASAPETSKVSVEIDTNSVNSNHAERDKHLRNEDFLDVSKFPKATFVSKSIEPAGDGKAKIVGDFTLRDVTKEITIDAEFVGAGSDPWGGERAGFKGTTTLALADYGITFDLGPAGKEVYLDLHVEGVKQ
>NC_022997.1|WP_023785644.1|216424_218146_+|iron-ABC-transporter-permease
MTLSTPSSAPPGPAGPFDPFKRLLRRRAPSRAAPGWGLAVSLALAVLALPVLAVVYLAATPDENVWPHLASSVLPESLRQTLLLGLGTGIVTLAAGTATAWLVTMYRFPGRAALDRLLVLPLAIPTYIAAYCYADLLDYAGPVQTSLRAYFGWSTPRDYWFPSIRSLGGAILVMSAVLYPYVYLAARATFVQQSVCALEVARTLGRSPMGVFWAVAFPLARPALAAGVALVLMETLNDLGAVQHLGVESLSAAIYATWLQRSNLGGAAQLATVMLGLIVVLLAVERIARGGAKVHHTTGRYRAIPFHDIQGWRGYLAAALCSIPFLIGFVVPCLLLVHYAFGHSAAALAGGFLMAAWNSILLATLAAVVALGFALLISYAPRVAPGPATRFAVRSAGFGYALPGTVLAIGVLIPLAALDNSVDALFRTTFGVSTGLILSGSIAALVYAYVIRFLAVALGGLEAGLERISPNLDAAARALGETAGSALFRVHLPLLLPALGAAGLLVFVDALKELPATLLLRPFNFETLATHVYAFAALEQIEAGALGALAIIAAGLIPLVALHRAIAGRAGNA
>NC_022997.1|WP_023785654.1|225138_225849_-|ATP-phosphoribosyltransferase
MTGAATEKLILGVPSKGRLMDETAAAFAQAGLTLRKTGNERGYRGEIVELPGVDVAFISASEIAWNLKIGRIHLGVTGEDLVSEQMSDAATRVTFLKKLGFGRADVIVAVPDCWIDVRTMADLSEIALPFRRAHGRWYRVATKYLNLTRRFFAARGLANYRIVESLGATEGTPAAGTAELIVDITTTGTTLAANGLRILDDGLILRSEACLIASNTADWSPATQGVLDEIKARMAG
>NC_022997.1|WP_023785655.1|225845_227024_-|ATP-phosphoribosyltransferase-regulatory-subunit
MPAETAKQFEALEASAQTLLSVFTRAGYEAVSPAIIQPAGVFLDVVGETLRARTYVFTDPDGDELCMRPDLTVPTCRLHVERHPEAAIPAKYSYNGPAFRFQPMGGDLAHTREFRQTGIESFGNANREQAEAEVVATIAGGLATAGLTGYALRFGDLGLLRAILRAADMPARWRRRLTHHFWHPPAFQAELKRLTTSPGAVSEHIPKPLREALDPDDPEAAESAVAAYLDTNGIEALGARTTAEITECLLDRVADARAEPLPARTAALIQSYVGIVVPARQSPERVRALAAEMGINIEAAVGAHEWRLELMSRAGVDLDRATFSAEFGRALQYYTGFVFEVVTKDLGPRSPVAGGGRYDHLLKAVGAPGHVPAVGAAVHTDRLLAALNGDAP
>NC_022997.1|WP_041316103.1|227352_228879_-|histidine--tRNA-ligase
MAKKEKDVNRRPVARLPKGMRDIGAAELRETQAMLEKIRAVYERYGFEPLETPAFEYTDSLGKFLPDQDRPNAGVFSFQDVAPEARDTKGDEQWLSLRYDLTAPLARHVAENFQDLPKPFRRYATGSVWRNEKPGPGRFRQFTQFDADTVGAESVAADAEMCMLAADTLEALGIERGQYVIKVNNRKLLDGLRETVGLAAAEDYERWLTVMRALDKYDRLGVEGVTALLGPGRKDESGDFTKGAGLDTAQIAAVTSIFTAAASIDEQLATLGARLSASAVGVEGLNELRTIWSLVTAAGYGDGRVAIDPSVVRGLEYYTGPVFEAELLIPATDDKGNPVRFGSVGGGGRYDDLVARFTGQKVPATGFSIGVSRLQAALAAIGRAPAPALGPVVVTVMDRDSLAEYQSFVQTLRNAGIRAELYLGNPKKFGRQLEYADKRGSPVVVIQGSTEREAGEVILKDLIEGAKAAAVISDNKEWKEARPAQISVPVANLVEAVREILARHRPAS
>NC_022997.1|WP_023785656.1|229029_230244_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MTVVLDTIQGARAEAPAVKPSLAGLSRAKLGEALAAAGVPEKQIRMRTTQLWRWIYVSGVTSFDQMTDVSKTLRQALEDRFTLDRPEIVTEQVSVDGTRKWLLRLPRRGHEARAPEIETVYIPESDRGTLCISSQVGCTLTCSFCHTGTQKLVRNLEASEIVAQILLARDRIGDWPGADRPDDQGMLPAADRKITNVVLMGMGEPLYNFDNVREAMEIAADGEGISLSKRRITLSTSGVVPEIARWGEEAGTMLAISLHAVTDELRNELVPINKKYPIAELMDACRNYPGLSNARRITFEYVMLKGVNDSLADAKALVRLLSGIPAKINLIPFNPWPNSRYECSEWETIETFADYVNNAGYASPVRTPRGRDILAACGQLRSESVRLRAREREAAEPATAASGG
>NC_022997.1|WP_144083468.1|230252_230675_+|hypothetical-protein
MLRTIGRLLWVAIAFLISMLAAMIVLTTLGLETITQAISNVDDADLMFDAYDFFWTGTLVLSGATLIPALLIVVVGEVGRIRSWLYYMIGGGAALVIIPLLARIDPAAIHQLALPSIWQVFATAGFAGGIVYWLLAGRNA
>NC_022997.1|WP_023785658.1|230775_231207_+|hypothetical-protein
MFVGIVRFVLGFAAAVLVAGLVQVLFVAGFDGVRTGGPVPIESMGLLILLAATQSAVFAAPFAALAAIVAAWLPTHSRLYFLAAGLVIGLGGFFAQHVGESGPHTILNRYALTAYAVSGLAAGFVYWLAGVQKPSRKAPTSSA
>NC_022997.1|WP_023785659.1|231308_231908_+|hypothetical-protein
MTYAVDPELTRRFTESCTTAAFGYARAATAAYAAFATQALDFWAQSAKGLERDDYKPSAPYLVTGPRNYRSALTPAPIEAAMPFDFFRLSNTVTASPMFAPVRAWWGLFPLEGDPKSWPMAYAMMTAGVPRAVALPAAEANMAAMEAAEVASTSIDRVFASYRTEGGFAMSSVTAPSKAMLQAFFVAPFATAAKLPWAA
>NC_022997.1|WP_144083469.1|231963_232776_-|hypothetical-protein
MVKTTTTSVLRAAAVFGAIASGTMPLAANEVLPWANTPPTVATAEPAAADPAVEAAIAQCTPLFEAACRDLNTCAWIADVSLQDGTVLPARCVARPSAPPKSTAKAKTPAPKKKTAETPKAPAAKPAAATETGTLPANAEPKAAAAAAPTVVTPPVAEKKAPEAPVKVSAPPPAAAPPAAKAAAVEPPPAKPAAAAPVAEKQPAAAPPPAEKTAATAPAPKAEQAPKSPVSAKAPAPSGGSMPGFGSFSSAFPAGGAVVTTTVPPKTSSE
>NC_022997.1|WP_023785662.1|233008_234244_+|argininosuccinate-synthase
MSGTDGKTNIRKVVLAYSGGLDTSIILKWLQETYNAEVVTFTADLGQGEEIEPARKKAEMLGIKPENIFIEDVREEFVRDYVFPMFRANALYEGIYLLGTSIARPLISKRQIEIARQTGADAVCHGATGKGNDQVRFELSYYALEPSIKIIAPWREWAFKGREDLLDFARRNQIPVAKDKEGESPFSIDANLLHSSSEGKVLEDPAQKPPEMVYQRTISPMDAPDKVTTIKIGFEKGDAVSLNGQKLSPATLLKALNDLGRDNGIGRIDLVENRFVGMKSRGVYETPGGTILLHAHRAIESLTLDRGAAHLKDELMPRYAELVYYGFWFSPEREMLQAAIDKSQEHVEGEVTLELYKGNVIVVGRESAKSLYTPNLVTFEDDKGAYDQKDAQGFIKLNALRLRTLAARDRK
>NC_022997.1|WP_081717793.1|234517_234787_+|hypothetical-protein
MSFAPASAAPAVAPSAVKAATQQASGIELVQRRDYRDRRGYRDRRGHSQRYRAGQRLKSAPRGYRRYDRRPSYWRTRNCVSVGPLWFCP

Crispr_ID: NC_022997_2

• CRISPR_ID: NC_022997_2
• CRISPR_location: 406065-406150
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DEDDh

Consensus repeat of NC_022997_2

Consensus_repeat	Method
TTTAGCCAGACCGATGATTCACGCTTC	CRISPRCasFinder

spacers of NC_022997_2

>2.1|406092|32|NC_022997|CRISPRCasFinder
AGGCTGGCAGGGTCTGAAGCGATCATGGTCTT

CRISPR arrays and Neighbor proteins around NC_022997_2

CRISPR arrays

The CRISPR arrays of NC_022997_2

>merge|NC_022997|2|406065-406150|CRISPRCasFinder
TTTAGCCAGACCGATGATTCACGCTTCAGGCTGGCAGGGTCTGAAGCGATCATGGTCTTTTTAGCGAGACCGATGATTCACGCTTC

>NC_022997|2|2|406065-406150|CRISPRCasFinder
TTTAGCCAGACCGATGATTCACGCTTC	AGGCTGGCAGGGTCTGAAGCGATCATGGTCTT
TTTAGCGAGACCGATGATTCACGCTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_041317031.1|414570_416601_-|thioredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|224250
NC_022997.1|WP_023785808.1|411373_411904_+|protoporphyrinogen-oxidase-HemJ	unknown	unknown	gnl|CDD|367596
NC_022997.1|WP_023785801.1|405544_406051_+|protein-export-chaperone-SecB	unknown	unknown	gnl|CDD|376817
NC_022997.1|WP_023785800.1|404451_405192_-|Tim44-domain-containing-protein	unknown	unknown	gnl|CDD|367895
NC_022997.1|WP_023785805.1|408381_408996_-|Maf-family-protein	unknown	unknown	gnl|CDD|167380
NC_022997.1|WP_023785803.1|406922_407543_-|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|234620
NC_022997.1|WP_023785798.1|402646_403297_-|Smr/MutS-family-protein	unknown	unknown	gnl|CDD|225396
NC_022997.1|WP_023785806.1|408985_409867_-|kinase/pyrophosphorylase	unknown	unknown	gnl|CDD|377080
NC_022997.1|WP_023785804.1|407539_408385_-|shikimate-dehydrogenase	unknown	unknown	gnl|CDD|234703
NC_022997.1|WP_023785802.1|406179_406905_-|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl|CDD|235574
NC_022997.1|WP_023785799.1|403302_404424_-|MltA-domain-containing-protein	unknown	unknown	gnl|CDD|225377
NC_022997.1|WP_023785809.1|412134_413400_+|transcription-termination-factor-Rho	unknown	unknown	gnl|CDD|236490
NC_022997.1|WP_081717603.1|413469_414387_-|sterol-desaturase-family-protein	unknown	unknown	gnl|CDD|225546
NC_022997.1|WP_051388614.1|399502_400249_+|DUF1223-domain-containing-protein	unknown	unknown	gnl|CDD|369071
NC_022997.1|WP_041317019.1|395705_396362_-|heme-ABC-exporter-ATP-binding-protein-CcmA	unknown	unknown	gnl|CDD|237421
NC_022997.1|WP_023785796.1|401318_401900_+|RNA-methyltransferase	unknown	unknown	gnl|CDD|349971
NC_022997.1|WP_023785795.1|400266_401247_-|NADPH:quinone-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|176203
NC_022997.1|WP_023785807.1|410279_411344_+|uroporphyrinogen-decarboxylase	unknown	unknown	gnl|CDD|234644
NC_022997.1|WP_023785797.1|401941_402466_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023785793.1|396618_399348_+|aconitate-hydratase-AcnA	unknown	unknown	gnl|CDD|236445

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_022997.1|WP_023785802.1|406179_406905_-|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	6.7e-43	141.3	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_041317031.1|414570_416601_-|thioredoxin-domain-containing-protein	gnl|CDD|224250	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones].	0
NC_022997.1|WP_023785808.1|411373_411904_+|protoporphyrinogen-oxidase-HemJ	gnl|CDD|367596	pfam03653, UPF0093, Uncharacterized protein family (UPF0093).	1.13673e-65
NC_022997.1|WP_023785801.1|405544_406051_+|protein-export-chaperone-SecB	gnl|CDD|376817	pfam02556, SecB, Preprotein translocase subunit SecB. This family consists of preprotein translocase subunit SecB. SecB is required for the normal export of envelope proteins out of the cell cytoplasm.	5.99616e-56
NC_022997.1|WP_023785800.1|404451_405192_-|Tim44-domain-containing-protein	gnl|CDD|367895	pfam04280, Tim44, Tim44-like domain. Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by electrostatic interactions and by penetrating the polar head group region. This family includes the C-terminal region of Tim44 that has been shown to form a stable proteolytic fragment in yeast. This region is also found in a set of smaller bacterial proteins. The molecular function of the bacterial members of this family is unknown but transport seems likely. The crystal structure of the C terminal of Tim44 has revealed a large hydrophobic pocket which might play an important role in interacting with the acyl chains of lipid molecules in the mitochondrial membrane.	1.71753e-47
NC_022997.1|WP_023785805.1|408381_408996_-|Maf-family-protein	gnl|CDD|167380	PRK02478, PRK02478, Maf-like protein; Reviewed.	9.51046e-66
NC_022997.1|WP_023785803.1|406922_407543_-|dephospho-CoA-kinase	gnl|CDD|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	2.27231e-78
NC_022997.1|WP_023785798.1|402646_403297_-|Smr/MutS-family-protein	gnl|CDD|225396	COG2840, COG2840, Uncharacterized protein conserved in bacteria [Function unknown].	5.71547e-30
NC_022997.1|WP_023785806.1|408985_409867_-|kinase/pyrophosphorylase	gnl|CDD|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	1.71836e-125
NC_022997.1|WP_023785802.1|406179_406905_-|DNA-polymerase-III-subunit-epsilon	gnl|CDD|235574	PRK05711, PRK05711, DNA polymerase III subunit epsilon; Provisional.	3.17743e-114
NC_022997.1|WP_023785799.1|403302_404424_-|MltA-domain-containing-protein	gnl|CDD|225377	COG2821, MltA, Membrane-bound lytic murein transglycosylase [Cell envelope biogenesis, outer membrane].	2.67759e-109
NC_022997.1|WP_023785809.1|412134_413400_+|transcription-termination-factor-Rho	gnl|CDD|236490	PRK09376, rho, transcription termination factor Rho; Provisional.	0
NC_022997.1|WP_081717603.1|413469_414387_-|sterol-desaturase-family-protein	gnl|CDD|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	8.30104e-28
NC_022997.1|WP_051388614.1|399502_400249_+|DUF1223-domain-containing-protein	gnl|CDD|369071	pfam06764, DUF1223, Protein of unknown function (DUF1223). This family consists of several hypothetical proteins of around 250 residues in length which are found in both plants and bacteria. The function of this family is unknown. Structurally it lies in the Thioredoxin-like superfamily.	2.29503e-86
NC_022997.1|WP_041317019.1|395705_396362_-|heme-ABC-exporter-ATP-binding-protein-CcmA	gnl|CDD|237421	PRK13539, PRK13539, cytochrome c biogenesis protein CcmA; Provisional.	3.77722e-87
NC_022997.1|WP_023785796.1|401318_401900_+|RNA-methyltransferase	gnl|CDD|349971	cd18098, SpoU-like, SAM-dependent rRNA or tRNA methylase related to SpoU. RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	1.85397e-60
NC_022997.1|WP_023785795.1|400266_401247_-|NADPH:quinone-oxidoreductase-family-protein	gnl|CDD|176203	cd08241, QOR1, Quinone oxidoreductase (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	1.26882e-151
NC_022997.1|WP_023785807.1|410279_411344_+|uroporphyrinogen-decarboxylase	gnl|CDD|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	3.01529e-177
NC_022997.1|WP_023785804.1|407539_408385_-|shikimate-dehydrogenase	gnl|CDD|234703	PRK00258, aroE, shikimate 5-dehydrogenase; Reviewed.	3.43391e-105
NC_022997.1|WP_023785793.1|396618_399348_+|aconitate-hydratase-AcnA	gnl|CDD|236445	PRK09277, PRK09277, aconitate hydratase AcnA.	0

Protein sequences

>NC_022997.1|WP_023785801.1|405544_406051_+|protein-export-chaperone-SecB
MAEEKKPTPQAAAGTDSNEVAVEAQIVGQFIKDLSFENPSLGKLLEGPAEPPSIKLEINVAAKKLKQDDFFESVIDFKAVASNKDGTIYDLEVLYAGLFRIKNMPEAALEPFLLVNCPTLTFPFLRRLVADITREGGFPPLLLDPIDFGQLFMRRKQDMAAAANSKPN
>NC_022997.1|WP_023785800.1|404451_405192_-|Tim44-domain-containing-protein
MDGEINLLTLLSLVVAVVAIIKLRSLLGRRTEEDESRIERKREAMNKQVAGAQSDKVVALPQRGRQAEPAEATVSVAEVEERIKAFAGADTQLATRLMDILRLDSTFEPETFIRGAKQAYEMIVTAFAEGNRRMLRDLLSADVLDSFSRAISEREQQNLVIDQSFVGINKADILEAEVSSKGIASITVRFVSQLISATRDKSGEIVDGDESRVKDVTDIWTFSRDISSKEARRNLNWKLVGTQSPN
>NC_022997.1|WP_023785799.1|403302_404424_-|MltA-domain-containing-protein
MPLGAPTSEPVSLAAAFSPVPFAELPGWGDDDHLAAFQAFARSAPALREAGERASGKTKAANAALVAAAELALSKADAITTRDAARAFFEQMFVPHRVEHKSTAGLLTGYYEPVLDASREASGAFRVPIYRRPPDLVNLVGEAERGALADAPTHARKTASGVEPYATRAEIEAGALAGEGLELVWLEDPVDAFFLHVQGSGRIRFADGESIRITYDGKNGHPYTSIGRYLIDTGAMAAEEMSLDALKVWLTAHPESARRVMQQNKSFVFFRELDGDADAPLGALGTGLSDGRSLAVDTGYHALGTPIYVAAPTLKPWGERSFEQLMIAQDVGSAIRGPERGDIYFGSGEDAGRLAGSTKHPGRFFVLLPRDAA
>NC_022997.1|WP_023785798.1|402646_403297_-|Smr/MutS-family-protein
MGKKPPHQPPRRRHLSKEDEALWDYMAASLKPIPGKKTRYIVGADDLEGVPPFELKADGKGKPGKKSALKAPPPPPPTSTAVPKPLSATPALNVFDRKAARKLRQGRFEIEARIDLHGMRQHEAHAALRGFLFSAFRRGLRWVLVITGKGISRREREDADYGFGTVERGVLRKNVPMWLAEPELRAIVVSYTAAAIPHGGEGALYVQLRNPERTRP
>NC_022997.1|WP_023785797.1|401941_402466_+|hypothetical-protein
MMALRSIPTLICSAVALLWATPLSAQSADGAVEKGRYGQWIVHQSAGDDPKICFAASQPQTKEPAGANRSAIVFYVSAWPKDGIKSEVSIKLGYPIRPDSPVAVEVGTDEFQLFAKDDRAYVADATDELKLIEALKKGNAVVVKATSARGTQTTDTYSLQGISRALQEMASACP
>NC_022997.1|WP_023785796.1|401318_401900_+|RNA-methyltransferase
MTSTNWPPKARGYFAIGAERSSKALNLGNLMRSAHAFGAGFTFTIGAQYQALEARADTSKGHWHLPHYNWDTPADLILPKGCRLVGVELIDEAVDLPSFRHPLQAAYVLGPERGSLSDALLERCDFTVKIPTSFCVNVAMAGAIVMYDRVKSLAPFAARPISEGVLSVTPVPPVRINTGGGGRVDDRAVSLPV
>NC_022997.1|WP_023785795.1|400266_401247_-|NADPH:quinone-oxidoreductase-family-protein
MKAALCKTLDGPEAVAVEEIAEPEAGAGEVVVRVRAAALNFFDTLITRGKYQTKPELPFSPGGEIAGVVERLGAGVTGFALGDRVAAAVGYGGAREKVVVPTESLIPVPAGVSDAVASGVSITFGTAIHGLKDRGNVKPGETVAVLGASGGAGQAAIEIAKLMGARVIACASSDDKLALCKALGADEVVNYDTADLKQALKDLTGGRGVDVVYDCVGDRYAEPAVRALAWEGRFLVVGFAAGEIPKLPLNLLMLKGAAAIGVFWSEAVRRNPAAHRANMVQVLDWVAAGKLEPRIHGLYPLAEVREAIGVIDRREAVGKVVLTMAD
>NC_022997.1|WP_051388614.1|399502_400249_+|DUF1223-domain-containing-protein
MPAAGLVLLATGLVSAQQPVPTHALGAGPPRAVIELFTSQGCADCPAADALLKTFVDRDDMVALTLPVDYWDYLGWKDTLAGPRNAERQRAYVERFGTGTVFTPQAVVNGTMEVLGSDANEIDRAIRATETALSSSRIPVLFWHFGNTIIIETGGAAPEAEPREATIWLAVVQRKVDVPIKGGENAGKTLTYYNVVRELTPVGVWNGRPATIRLARAAIMRPETEDLIVLIQEAETGPILGAARLMGN
>NC_022997.1|WP_023785793.1|396618_399348_+|aconitate-hydratase-AcnA
MSAPTTVTSAPASLDSFNCKRTLTVDGREYVYYSLPEAEKNGLPGISKLPYAMKVLLENLLRHEDGRSVTKADIEGAAEWLDNRGRAEREIGFRPARVLMQDFTGVPAVVDLAAMRDGMLKLGGDAKKINPLVPVDLVIDHSVIVDDFGNPQAFANNVELEYERNGERYVFLKWGQDAFANFRVVPPGTGICHQVNLEYLAQTVWTATNGNGETLAYPDTLVGTDSHTTMVNGLAVLGWGVGGIEAEAAMLGQPQSMLIPEVIGFELTGALKEGVTATDLVLTVTQMLRKKGVVGKFVEFYGAGLNTLTLADRATIANMAPEYGATCGFFPVDTETLNYLVVSGRDAQRVALVEAYSKAQGLFRTADAADPVFTDTLSLDLSTVGPSLAGPKRPEGRIALSDVKDGFGTALAGEYKKTGDTEQRFAVAGRDFDLGHGDVVIAAITSCTNTSNPSVLIAAGLLARNAAEKGLTSKPWVKTSLAPGSQVVAAYLDKAGLQPYLDKVGFNLVGFGCTTCIGNSGPLAPEISKTINDNGLVAAAVLSGNRNFEGRVSPDVQANYLASPPLVVAYALAGTVTRDLSTEPLGLGSDGSPVYLKDIWPSNQEVQKFIAENISRDLFKSKYADVFRGDEHWATIKTSTGLTYSWDAKSTYVQNPPYFDGITKTPRPITDIEGARVLALFGDKITTDHISPAGSIKAASPAGKYLLDEGVEPRDFNQYGTRRGNHEVMMRGTFANIRIKNHMVTDEAGNVVEGGYTIHHPSGERLAIYDAAQRYAEEKVPLVVFAGVEYGNGSSRDWAAKGTNLLGVKAVIAQSFERIHRSNLVGMGVIPFVFEAGTSWQSLGLDGSETVTLKGVAGLKPRQIVDAIITKTDGSQSKVPLICRIDTLDEIEYFKNGGILSYVLRNLAA
>NC_022997.1|WP_041317019.1|395705_396362_-|heme-ABC-exporter-ATP-binding-protein-CcmA
MQLHADNLTVERGTRTVIANLTFTANAGEALLLTGPNGAGKTTLIRTVAGFIAPVSGKIALKGDVGDRDIAELCHYVGHLTGVKANLTAEQNLAFWAEYLGGETTRAMAERVDDALDAFGLLGLADYPAGLLSAGQKRRLGLARLLVAERPIWLLDEPTVSLDAASTTLLAGLIQRHLANDGLVIAATHLPLGLEQPSYLRLGPTAPTVEGSAQGAAL
>NC_022997.1|WP_023785802.1|406179_406905_-|DNA-polymerase-III-subunit-epsilon
MLREIVLDTETTGLDPRKGDRLVEIGCIEIVNRNPTGREFHQFINPERTVPAEAEAVHGLSTQFLLDKPVFADVAGDFLDFIAGDTLVIHNATFDVGFLNAELERLKLGPLAMSRVVDTLQLARRKHPAGPNSLDALCKRYGIDNSKRIKHGALMDSLLLAEVYVELLGERQATLGLGSNRGSAARDGRTGGPAKPAARPAPLAPRLSAAEIEVHRAFVETLGENALWKRYLASEKTDDAA
>NC_022997.1|WP_023785803.1|406922_407543_-|dephospho-CoA-kinase
MIVVGLTGSIGMGKSTIADMFRRRGIPVFDADAEVHRLYTGEVTAAVEAAFPGTTEDGRVDRVRLAAALNNDETRFRKLEAIVHPLVRASERRFLHTAHESHAATAVLEVPLLFETGRDKQVDAVVVVSAPADVQRARVLARPGMTPEKLDGLLARQTPDEEKRQRADFVVDTGGTLADSEAQVDAILDSLKSKPAEAYARHWQDL
>NC_022997.1|WP_023785804.1|407539_408385_-|shikimate-dehydrogenase
MKRAGKQACVIGWPIEHSRSPAIHGYWLDRYRIDGTYTKEAVRPEDVETFLRGLANAGFSGCNVTIPHKEAAFRIADERDASAVAVGAANTLWLEGARLCAANTDTYGYMTYLALQAEDWNRRDAPVSILGAGGAARAIVHGFLEADVGEIRLFNRSAERAATLAADFGPRVKVFPWEQRSRAATESAVLVNTTAVGLKGEGSLDMDFTDFHPDCIVSDIVYVPLETALIRDARRHGLHTVDGLGMLLHQAVPGFEKWFGVRPEVTDELYDKIAADIEGAR
>NC_022997.1|WP_023785805.1|408381_408996_-|Maf-family-protein
MRRNAPHLVLASGSATRRAMLEAAGIAVTVTPADVDEAAIRDGLLADTPGLPHARIALALAEEKAKAVSAQHKHALVIGADQVLSFEGRLFEKPRDMDDARASLVALRGKTHTLHSAVALGVNGETVWHDVAVAHLTMRAFSNNALDGYLARVGDVVLTSVGAYQIEGPAVQLFAAVEGDHATILGMPLLPLVAELLRRGVLEA
>NC_022997.1|WP_023785806.1|408985_409867_-|kinase/pyrophosphorylase
MTNSRPSYFHLHLVSDSTGETLTTIAKAAAVQYSQMRPIEHMHPLVRNARQLKRVLQEIEQAPGIVLYTIVNTDLISEIEQRCKELKVPCYAVLQPIMQVFESYLGAPQTPTVAGQHVLDADYFRRIDALNFSMAHDDGRLPDNLNEADIILLGISRTSKTPTSIYLAQRGYKTANVPIVPGLPFPEELAGDHTAFVACLIASPDRIAEVRRNRALLIGDRDLDDYVDRSRIAAEIAITRKLCAKHGWPVIDVTRRSVEETAATIIRLMQDKEAEERAAAEDKETAAESGHEA
>NC_022997.1|WP_023785807.1|410279_411344_+|uroporphyrinogen-decarboxylase
MALGGEGGLKTAERKFLAPFRGEALKVPPIWLMRQAGRYLPEYRATRTEAGGFLNLCYTPALAAEVTLQPIRRYGFDAAILFSDILVVPDALGQEVRFEEGEGPRLDPIRSATDLSRLDVGATGTKFALVAETVQRLRQDLPAETALIGFCGAPWTVATYMVQGRGSPDQAEARLWAYRDPEGFADLIDTLVETSVEYLDLQVKAGADCLQIFDTWAGSLPDDEFDRWVVAPTRQIREAIKDRHPDIPVIGFPRGAGAAVVWYVAETGVDGVSFDTAAPPFLMSETFEEDDVVVQGNLDPLLLVAGGARLDARVDEILDLMQGKRFIFNLGHGIVPQTPPEHVAQLVERVRSRR
>NC_022997.1|WP_023785808.1|411373_411904_+|protoporphyrinogen-oxidase-HemJ
MTRASDEHASPGKRAAVAVAITAVLCLVAVLLLGPDAYLWLKAVHVMAVISWMAGMLYLPRLFVYHSEAVPGSELSETLKVMERRLLRIIVNPAMIAAWVLGLWLGWQGGLFGTGWFHAKLALVLTLSGVHGYYSAAVRRFAEDRNTASTRHWRIWNEVPAALMAGIVILVVVKPF
>NC_022997.1|WP_023785809.1|412134_413400_+|transcription-termination-factor-Rho
MTEMKLEDLKLKSPTELLSFAEEVGVENASTLRKQELMFATLKQLAAKDIDITGVGVVEVLQDGFGFLRSPDANYLPGPDDIYISPSQIRRFALRTGDTVEGEIRSPKEGERYFALLKVNRINFEDPEAVKHKIHFDNLTPLYPTSWLKMEIEDPTIRDLSARVIDIVVPLGKGQRALIVAPPRTGKTVLLQNIAHSITANHPECYLIVLLIDERPEEVTDMQRSVKGEVISSTFDEPASRHVQVSEMVIEKAKRLVEHKRDVVILLDSITRLGRAYNTVVPSSGKVLTGGVDSNALQRPKRFFGAARNIEEGGSLTIIATALIDTGSRMDEVIFEEFKGTGNSEIILDRKVSDKRVFPAIDVSRSGTRKEDLLVPKDQLKKVYVLRRILNPMGTMDAIEFLIDKLRSTKTNGEFFQSMNT
>NC_022997.1|WP_081717603.1|413469_414387_-|sterol-desaturase-family-protein
MVLGLNGAAYYVVAYGHSYAWLALLIGILLATAFAAERILPWYEEWNHSHGDEKTNIFHAIVYEAQNLNGILTIPLVAWLTSGSLNAGIWPTDWPILAQLILAVVLADFALTYLHYLSHRFSFLWRLHAVHHGVARLYGFNGLVRHPLHQIIDLVLGTAPLALAGMPVEVAALLGFVITVQLVVQHSNVAYALGPLRNHLAIGQIHHLHHVNWGKEGDCNFGLFFTIWDRMLGTFHPEPPRPITARDMGVDEVPDFPKRYMDQLAFPLHYKPGEGVQSGLKTKAETQKPPQTAAAQARALHDAAE
>NC_022997.1|WP_041317031.1|414570_416601_-|thioredoxin-domain-containing-protein
MSRNRLGDESSPYLLQHKDNPVHWWAWGPEALAEAKTTGKPILLSVGYSACHWCHVMAHESFEDDETAAVMNERFVNIKVDREERPDIDAIYMGALHKLNQQGGWPLTMFLDSDARPFWGGTYFPKVPTYGRPAFIEVLERISDAYHQQPEKVAGNANAITEALAEMTESGAGPEVTDPLIREITGRLAHLVDPTHGGITGAPKFPQWSFFWLLWRGAIRYRNDAAKQAVITTLERMSQGGIYDHLGGGFARYSVDELWLVPHFEKMLYDNALLIDLMTEVWRETKSPLLQARVAETVAWLSREMVVEGGGFAAALDADSEGEEGKFYVWSAEEIERVLGAEDAAVFAKAYDVTLDGNWEGHTILNRLDAKTLGSDGEDAKLVALRAKLLDARAGRIRPGWDDKVLADWNGLMIAALARAGIVFDRSDWVTMARTAFTYVTEKMTVDGRIVHSIRHGRGRAPGTAHDYANMIWAALRLYQATGENAYLAKAIEWVAILDRHYWSEDAGGYFTAADDTSDVIVRLRTASDDATPAANATMVSNLAALATLTGDSRFVRRAESIMRAFSADLAKNLVAHTGLLAAAMDLLAPQLVVIVASESEPHSALGAVARSMSIPGAVELEVRGAIGALGPPALHGKSAEDGRSTAYVCVGPQCSLPANSEAQLRQAVLDLRSVA

Crispr_ID: NC_022997_3

• CRISPR_ID: NC_022997_3
• CRISPR_location: 677261-677343
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_022997_3

Consensus_repeat	Method
TAGGGCCTGAAGCGATCATGGTCT	CRISPRCasFinder

spacers of NC_022997_3

>3.1|677285|35|NC_022997|CRISPRCasFinder
CTTGAGTTAGACCGATGATTCACGCTTCAGGCTGG

CRISPR arrays and Neighbor proteins around NC_022997_3

CRISPR arrays

The CRISPR arrays of NC_022997_3

>merge|NC_022997|3|677261-677343|CRISPRCasFinder
TAGGGCCTGAAGCGATCATGGTCTCTTGAGTTAGACCGATGATTCACGCTTCAGGCTGGTAGGGCCTGAAGCGATCATGGTCT

>NC_022997|3|3|677261-677343|CRISPRCasFinder
TAGGGCCTGAAGCGATCATGGTCT	CTTGAGTTAGACCGATGATTCACGCTTCAGGCTGG
TAGGGCCTGAAGCGATCATGGTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_023786064.1|684609_685872_+|aspartate-kinase	unknown	unknown	gnl|CDD|235843
NC_022997.1|WP_023786052.1|671322_671628_+|pH-regulation-protein-F	unknown	unknown	gnl|CDD|180435
NC_022997.1|WP_023786056.1|675468_676452_+|complex-I-NDUFA9-subunit-family-protein	unknown	unknown	gnl|CDD|187579
NC_022997.1|WP_023786058.1|677471_678749_+|phosphopantothenate-synthase	unknown	unknown	gnl|CDD|172484
NC_022997.1|WP_041317210.1|669452_671000_+|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl|CDD|237163
NC_022997.1|WP_023786063.1|683604_684402_-|bifunctional-2-polyprenyl-6-hydroxyphenol-methylase/3-demethylubiquinol-3-O-methyltransferase-UbiG	unknown	unknown	gnl|CDD|235350
NC_022997.1|WP_023786051.1|670996_671326_+|Na+/H+-antiporter-subunit-E	unknown	unknown	gnl|CDD|237159
NC_022997.1|WP_023786049.1|669069_669453_+|NADH-quinone-oxidoreductase-subunit-K	unknown	unknown	gnl|CDD|183658
NC_022997.1|WP_023786060.1|679529_680528_+|cysteine-synthase-A	unknown	unknown	gnl|CDD|273463
NC_022997.1|WP_081717612.1|672085_673462_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|99747
NC_022997.1|WP_041317230.1|682180_683386_-|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl|CDD|178031
NC_022997.1|WP_023786055.1|674077_674926_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187632
NC_022997.1|WP_051388502.1|678782_679370_+|dUTP-diphosphatase	unknown	unknown	gnl|CDD|234802
NC_022997.1|WP_023786057.1|676511_677174_-|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NC_022997.1|WP_023786067.1|689569_690469_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl|CDD|236467
NC_022997.1|WP_023786066.1|688494_689580_+|peptide-chain-release-factor-1	unknown	unknown	gnl|CDD|234801
NC_022997.1|WP_023786065.1|686039_688301_+|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl|CDD|226133
NC_022997.1|WP_144083491.1|680564_681992_+|SEL1-like-repeat-protein	unknown	unknown	gnl|CDD|276807
NC_022997.1|WP_023786048.1|668669_669068_+|cation:proton-antiporter	unknown	unknown	gnl|CDD|237122
NC_022997.1|WP_023786053.1|671624_672005_+|monovalent-cation/H(+)-antiporter-subunit-G	unknown	unknown	gnl|CDD|237169

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_023786064.1|684609_685872_+|aspartate-kinase	gnl|CDD|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
NC_022997.1|WP_023786052.1|671322_671628_+|pH-regulation-protein-F	gnl|CDD|180435	PRK06161, PRK06161, putative monovalent cation/H+ antiporter subunit F; Reviewed.	6.33111e-15
NC_022997.1|WP_023786056.1|675468_676452_+|complex-I-NDUFA9-subunit-family-protein	gnl|CDD|187579	cd05271, NDUFA9_like_SDR_a, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs. This subgroup of extended SDR-like proteins are atypical SDRs. They have a glycine-rich NAD(P)-binding motif similar to the typical SDRs, GXXGXXG, and have the YXXXK active site motif (though not the other residues of the SDR tetrad). Members identified include NDUFA9 (mitochondrial) and putative nucleoside-diphosphate-sugar epimerase. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.86366e-112
NC_022997.1|WP_023786058.1|677471_678749_+|phosphopantothenate-synthase	gnl|CDD|172484	PRK13982, PRK13982, bifunctional SbtC-like/phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Provisional.	0
NC_022997.1|WP_041317210.1|669452_671000_+|Na+/H+-antiporter-subunit-D	gnl|CDD|237163	PRK12663, PRK12663, Na+/H+ antiporter subunit D.	4.09847e-165
NC_022997.1|WP_023786063.1|683604_684402_-|bifunctional-2-polyprenyl-6-hydroxyphenol-methylase/3-demethylubiquinol-3-O-methyltransferase-UbiG	gnl|CDD|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	4.48788e-134
NC_022997.1|WP_023786051.1|670996_671326_+|Na+/H+-antiporter-subunit-E	gnl|CDD|237159	PRK12651, PRK12651, Na+/H+ antiporter subunit E.	4.86395e-36
NC_022997.1|WP_023786049.1|669069_669453_+|NADH-quinone-oxidoreductase-subunit-K	gnl|CDD|183658	PRK12658, PRK12658, Na+/H+ antiporter subunit C.	3.79022e-41
NC_022997.1|WP_023786060.1|679529_680528_+|cysteine-synthase-A	gnl|CDD|273463	TIGR01136, Cysteine_synthase, cysteine synthase. This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family].	6.26012e-154
NC_022997.1|WP_081717612.1|672085_673462_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|99747	cd06454, KBL_like, KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS), 8-amino-7-oxononanoate synthase (AONS), and 2-amino-3-ketobutyrate CoA ligase (KBL). SPT is responsible for the condensation of L-serine with palmitoyl-CoA to produce 3-ketodihydrospingosine, the reaction of the first step in sphingolipid biosynthesis. ALAS is involved in heme biosynthesis; it catalyzes the synthesis of 5-aminolevulinic acid from glycine and succinyl-coenzyme A. AONS catalyses the decarboxylative condensation of l-alanine and pimeloyl-CoA in the first committed step of biotin biosynthesis. KBL catalyzes the second reaction step of the metabolic degradation pathway for threonine converting 2-amino-3-ketobutyrate, to glycine and acetyl-CoA. The members of this CD are widely found in all three forms of life.	1.78747e-141
NC_022997.1|WP_041317230.1|682180_683386_-|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl|CDD|178031	PLN02409, PLN02409, serine--glyoxylate aminotransaminase.	1.99921e-149
NC_022997.1|WP_023786055.1|674077_674926_-|SDR-family-oxidoreductase	gnl|CDD|187632	cd05374, 17beta-HSD-like_SDR_c, 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. 17beta-hydroxysteroid dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.67505e-85
NC_022997.1|WP_051388502.1|678782_679370_+|dUTP-diphosphatase	gnl|CDD|234802	PRK00601, dut, dUTP diphosphatase.	1.83247e-82
NC_022997.1|WP_023786057.1|676511_677174_-|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.88505e-14
NC_022997.1|WP_023786067.1|689569_690469_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl|CDD|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	6.24042e-89
NC_022997.1|WP_023786066.1|688494_689580_+|peptide-chain-release-factor-1	gnl|CDD|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NC_022997.1|WP_023786065.1|686039_688301_+|phosphoenolpyruvate--protein-phosphotransferase	gnl|CDD|226133	COG3605, PtsP, Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms].	0
NC_022997.1|WP_144083491.1|680564_681992_+|SEL1-like-repeat-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.93126e-34
NC_022997.1|WP_023786048.1|668669_669068_+|cation:proton-antiporter	gnl|CDD|237122	PRK12509, PRK12509, Na+/H+ antiporter subunit B.	1.80214e-39
NC_022997.1|WP_023786053.1|671624_672005_+|monovalent-cation/H(+)-antiporter-subunit-G	gnl|CDD|237169	PRK12674, PRK12674, putative monovalent cation/H+ antiporter subunit G; Reviewed.	6.60163e-27

Protein sequences

>NC_022997.1|WP_023786057.1|676511_677174_-|hypothetical-protein
MTVLSRHSRNYRLAALLTGALLACAMPAGAASTSTSECFSQNNERRIAGCTDLIENPNIDAGTKSLAYAMRALALSLKGKLDESLPDYDRAIELDPGSAMSFNNRAWVKYKLNRLEDGLEDVERSLVLGPASPHAHDTRAHIRQALGERRPALRDYERAMRLGGEPLVRLYQCGLEAAGFYKGPIDGLYTRDVRSALEACVDTTECDPLPPDEECRAAMS
>NC_022997.1|WP_023786056.1|675468_676452_+|complex-I-NDUFA9-subunit-family-protein
MAPQGGSNSLVTIFGGPGFVGRHAVRALAQNGYRIRAASRRPDLAGHLQPMGDVGQIQPVQANLRFPDSVARAVEGVDAVVNAVGILAPSGAQTFAAVHVDGARAVAKAAKAAGARRFIHVSAIGASAASRAHYAQTKAAGEAAVLEEFPEAVILRPSIVFGPEDEFFNRFASLARVSPVLPLIGGGHTRFQPIYVGDLAAAIAAVVNGAGTPGTVYELGGPEVLTFRELMERTLLYADRRSKLVSLPFWLAKLQALATWPLPNSLRPLTVDQVRLLQSDNVVSDEALKQGRTLAALGVDVPDAIGSIVPGYLERFRSKGQYWRYRG
>NC_022997.1|WP_023786055.1|674077_674926_-|SDR-family-oxidoreductase
MKNVIVTGTSSGIGLDTVVALAKQGWRVFATMRKTAKSGPLESALVDAGLRDRVEIAQLDVTDAASISAAVEAVLSKTGGQLDAVVHNAGVAVGGAFEDIRDDQSRHVMETNFFGVVALTRALMPTFRNQRHGRVLIVSSDAAFMGQPGNAIYCASKWAIEGWAEAAAHELNLFGIEAILVEPGPYRTPIWENSPHIMPPESPYYAWSQQLFKAADEHTERTARDPIEVARVIVKALEAQRPRFRYPVGPLARITHAVRGKIPSRLMRRGVSRLLGLHRIRA
>NC_022997.1|WP_081717612.1|672085_673462_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MRRDRAEAPPSAVPRRTHPRSRLAANTGVAPARRKPKEYLVLNLIPQTKNWLRANGDRPVAAKPFSSLSSYKAIKHHQTLAKTLGIPNPFYRSTEGMADKLTLIDGKPVLNFAWCDYLGLSQHPEMIAAANEATSRFGTTLSASRMVSGDTPMHRELEAEIARTIGVEAALVFVSGHAANVSTIGTLMNSDDLIVHDEFVHNSAVVGMRLSGAETRSFKHNRLDALENILRTERAKYRNVMVVIEGLYSTEGDLPDLARIVELKERYGAWLMVDDAHGCGVLGATGRGLAEHCGVDGAKVDIWMGTLSKAYASCGGYIAGNTELIDLLRYAAPGFVFSVGLPPAMTASALTALRIVQREPERVQRLHNNSKMFLEGAHARGLDTGRAAGIAMLPIMVGLTGRAAKTVARVLERGVNASFIMYPGVPMNAARLRFFLSSELTEAEINLALDVTKEELGR
>NC_022997.1|WP_023786053.1|671624_672005_+|monovalent-cation/H(+)-antiporter-subunit-G
MTAWIGAFFLVLGATVCLVAAIGVLRFPDFFMRMHAATKAGVAGAGLVLIGIGFAMPSFEIALKIVLANLFLLLTVPVAGHLLGRAGYIAGVPLWGATQRDELASVLPRGAFDRALQSVGDDVKPD
>NC_022997.1|WP_023786052.1|671322_671628_+|pH-regulation-protein-F
MSGVAALEIAAIIAGVLLAAAAVCAALRIVRGPSTPDRVVALDMLSLIGVAVAGLAVLVSGSTAFVDVALGVALVGFLAVVALASFIERGAIRDDDNEDAP
>NC_022997.1|WP_023786051.1|670996_671326_+|Na+/H+-antiporter-subunit-E
MSFATKAVAWGRLGALFFREFALSVKDVSLAVLDPRRPLRPAIVAVPLDVKSDAGITLLANMITLTPGTTSLHVSEDRKTLYVHAMNASESTVADIKAGFEAKVREVLA
>NC_022997.1|WP_041317210.1|669452_671000_+|Na+/H+-antiporter-subunit-D
MRANLLLALPVLCPLAGVALSLLAWRWPLVQRGVSLAASFGLLLSAIALVGAVHDGTVLATQFGAWQAPFGISFVGDMLSAAMVLIAGLMAVAVGIYGLAGDASAREYAFYHPLYQGLLLGVTGAFLTGDIFNLYVWFEVMLISSFGLLALGGTKAQLDAGVKYVTLNLVVTTQFLIAVALLYGATGTLNMADLALVLPTVENQGLVTTLALLFLVAFGAKAAVFPLFFWLPAAYHTASAPVVAIFAALLTKVGVYAILRTFTLMFDGDTGVTAPIVGAIAAATMITGVLGAAAHFDIRRILSFHIISQIGYMLLGIAVATPLAVGGAILYVIHHIVVKANLFLVAGVIHRAGGSYHLKEIGGLYRGLPLLGVLFAIPALSLAGLPPLSGFWAKFGVIKASLDAGHIALAVTGLAVGLLTLYSMLKIWNEAFWKAAPERSVAAERRWLGEPGTRVLMLVPISALATITLAIGFWAEPFVDYSLRAGAQLLDKSAYIDAVFPPETAGGARIQESVP
>NC_022997.1|WP_023786049.1|669069_669453_+|NADH-quinone-oxidoreductase-subunit-K
MEPIFALAFGVMIAVAAYLILSRNMLRVLLGLLVLGNAANLAIFLAGRLGSRVPPLVEAGEATVAVSANPLPQALILTAIVISFSLVAFTAVLFENAYKRLGTLDPDAMRDAETPPGEGLRDDERRE
>NC_022997.1|WP_023786048.1|668669_669068_+|cation:proton-antiporter
MNSLILRTTGRAILPLALLFSIYVLFRGHNEPGGGFIGGLIAAAGLAVYALPRGRSALVRLIRVWPKALIGGGLALGLLSGLPALLLNSPYLTHQWTFPGGLAVGTALVFDVGVYLTVVGAVLTFLLPYLEE
>NC_022997.1|WP_023786058.1|677471_678749_+|phosphopantothenate-synthase
MKRVLLIIGGGIAAYKSLDLIRRLKERGMSVRCVLTKGGQEFITPLAVGAISNEHVATDLFDLNAEREIGHIRLAREADVVVVAPATADLLARMAQGQANDMATAILLATRAPVLAAPAMNPAMWAHAATQRNVKQLAADGVAFIGPNAGEMAERGEAGVGRMAEVAEIVPRVEQLLEGESEARRGFGFIDVADRRPSGGKLPLAGRHVLVTSGPTHEPIDPVRYIANRSSGKQGHAVAAAAQKLGARVTLITGPVEIADPEGVTVQHVETAQEMLTAVEAALPADVAVFAAAVADWRVASAAEGKIKKAKGAPPPALHLAENADILATVARLKPRRRPQLVIGFAAETDAVVENAERKRSAKAVDWIVANDVSQGSGVFGGERNTVHLVTAQGVENWPQMSKADVAAALIGRAARYLAQSVEQV
>NC_022997.1|WP_051388502.1|678782_679370_+|dUTP-diphosphatase
MAVTVRVVVLNHGEGLALPAYQTDDAAGLDLVAAVPEGKPVQIAPGARALVPTGLQIELPRGYEAQVRPRSGLALKHGVTCLNSPGTIDADYRGEVGVILANLGQEPFAVSRGDRIAQLVVAPVTRAVLRPVAALSTTRRGAGGFGSTKTKTALKAAKSPARAAAKAAPNRQSQKKVKAGATPRPKPPRKKAVKS
>NC_022997.1|WP_023786060.1|679529_680528_+|cysteine-synthase-A
MADTEIKTLNATKSWGRGRVYNDITETIGHTPLVKLGRIAKAAGAKADVLMKLEFFNPLSSVKDRIGVAMIDVLEAEGKIAPGKTVLVEPTSGNTGIGLAFVAAARGYELKLVMPESMSVERRKILAHLGADLVLTPAAGGMPGAIDKANQLLAEIPGAVQPSQFENPANPLVHEKTTAEEIWTDTGGKVDVLVIGVGTGGTLSGCGRVLKARKPDLKIVAVEPEGSPILSGGARGPHKIQGIGAGFVPKVLDTSLIDEVVRVSNESAFETSRSLAKTEGIPGGISTGANLWAALQVAARDELAGKTVVTFAPSAAERYFTGELFLDPPAKA
>NC_022997.1|WP_144083491.1|680564_681992_+|SEL1-like-repeat-protein
MVRPSLIAAACALFVAASGLSSASAEPDEVRLAQRWTPLTGILPPEREVRDPGPETGSLDRAVPAEAAEAPDSNVQTGRRLLQAALVRVVTDGQPHGGLDVQSTLVDADLAQALGLGEQRGAMVTDASSSSARGANLRIGDVIQRVGSHSVAGPNGLHQVLRESSPDDLVTVEVWRAGEGAADLKQFLMDRAEAGNVGAAASLGRLLSLGLVLGPRNPAEAAPYYLKAAEAGHLASMTRYALFAKDGVGVPKDEAVAARWFRKAADGGQDAAMTNLGGLYEAGLGVKQDDAEAALWYRRAVEKGHVFANYRLGLLYEAGRGVGRDHQEAARLLRAASDGGLSEATSWLADKYAQGRGIPKDEAEAAKLNAVAADQVRRAANRGNAVATFNLGILYRLGKGVPQSDTEAAYWVVKSLRLGDRYLVAELMRNPDVLAIADRKWLQGVLRDEGTYKGPINGTFSPDVRAAMDALANPA
>NC_022997.1|WP_041317230.1|682180_683386_-|aminotransferase-class-V-fold-PLP-dependent-enzyme
MSNAPRRPGRHFLQIPGPTPVPERVLSAMSRQMLDHRGADFQKLGKSVLSGIKTIFKTTGPVIIYPSSGTGAWEAALTNTLSPGDRVLMVETGQFAVLWKQMADRLGLRAEVIQTDWRIGADPAEIEEHLRRDTDRLIKAVCVVHNETSSGCMTPLEEIRRALDAADHPALFMTDTISGLGTADLRHDEWGIDVTVSGSQKGMMLPPGLSFTAVSEKALAASRTAKLARSYFSWDDMLSNNANGFFPYTPATGLLYGLDEAIKLLHEEGLDNVFARHARLGAATRAAVRTWGLEINCRDPKYYSQAVTTVLVPEGHNADALRALALDTFDISLGTGLNKLATKAFRIGHLGDTNDLTVMGALTGVEMSLELAGIPHKKGGVQAAMAVITDSMNKSPRAEAA
>NC_022997.1|WP_023786063.1|683604_684402_-|bifunctional-2-polyprenyl-6-hydroxyphenol-methylase/3-demethylubiquinol-3-O-methyltransferase-UbiG
MTDHAERPPSKSPQPGTREPGARNVDAAEVARFQRMAQAWWDPTGDFRPLHQIAPARLAFVRDALTRHFERDIGGRYPLKDLTALDVGCGGGLMSEPLARLGARVTGIDPGEENVAIAREHAAAQGLDIDYRATTAESLLAAGETFDAVLALEVVEHVPDVGAFVRTCAGLVRPGGIIVLSTLNRTAKSYALAIVAAEYVLGWLPRGTHQWDRFVTPDELAGHLAAAGLSAPRFRGMAYSPFRDDWSLTDDIDVNYLAAAAKPGE
>NC_022997.1|WP_023786064.1|684609_685872_+|aspartate-kinase
MAVVVMKFGGTSVADVERIKNVARHVKREADAGNKVAVVVSAMAGATNQLVGWVNEAAPLHDKREYDAVVASGEQVTAGLTAMVLQSMGVKARSWQGWQVPIETNTAHGSARIAGIPGDDLRRSLDAGEVAVITGFQGVEPKARRIATLGRGGSDTSAVAIAVALKADVCDIYTDVDGIYTTDPRIVPKARRLAKVSYEEMLEMASSGSKVLQTRSVELAMVHQVRTRVLSSFTKPEDMAPVGAAPLESVGTIVCGEDEIMETQVVSGIAYARDEAKITMLKLEDKPGIAARIFGPLSDAAINVDMIVQNVAADGHHTDMTFTVQQAELARAVDVLNAAKADIGEFEIQSSADVAKVSVIGIGMRSHAGVAAQMFKALAEKGINILAISTSEIKISVLIDAAYAELAVRTLHSLYGLDAA
>NC_022997.1|WP_023786065.1|686039_688301_+|phosphoenolpyruvate--protein-phosphotransferase
MPTEPALRVIMRRLREIMSESAADGQERLDKIVRQIAGVMVADVCSLYLKRQDGSLELFASEGLNRTAVHTTMLKRGEGLVGRCAEMGVLINEPDASKHPAFSYRPETGEEIYHSLLAVPVQRSGQVLGVLVVQNRTVKEYSDEDAEVMQATAMVVAEHLVSGAVSGFGAGIEISKALSLVVKGEPISEGIALGHVMLHEPRIVVTKLMADDPVAELRRLEDALLELKTSLDEMLSHELLSGAGDHRDVLEAYRMFAHDRGWERRLREAVQSGLTADAAVERVQNGTRARMLRQPDPFWRERQRDLDDLSDRLLRILAGRATGFVNPPEMPSDTILVARNMGPAELIDYDGSRLRGLVIEDGSGQSHVAIVAKALGIPAVGQATGLVERVTAGDAIIVDGVAGEVHVRPSSDVVNAYTDKVRFRARRQKQYEKLRDLPAVTKDGERIALQINAGLLQDMPHLAESGGDGIGLFRTELMFMLSHSLPRVDRQTEAYSAILQEAKGKPVVFRSLDIGGDKILPYLRQIPEENPAIGWRAIRMSLDRPALFRMQIRALLRAAAGQQLRVMLPMIAVATEMDEARALIDKEWALAKARGSLLPSELLIGAMIEVPSVLFELDELLPRVDFVSVGSNDLMQFLFAADRSNPRVVNRFDSLSAAPLKALKMLAGACYRHNVPLTVCGEMAGRPIEAMCLIGLGFRTFSMAPASIGPVKAMIRSLDGSAVTDLLDDLLVSGSGSLRAEIEAFAARSKVEI
>NC_022997.1|WP_023786066.1|688494_689580_+|peptide-chain-release-factor-1
MSVIPQEKLAKLVERYETIQAELNQGAPQATYVKLTKELSELTPLISAVRDLEAAQTEKRDLEALLRDPGQDKDMAEMAREELDQIGERIEALGQQLRVLLLPKDAADEKSAILEVRAGTGGDEAALFAADLYRMYQRYADLHGWKTEILSMSESDLGGYKEIIASITGRGVFAKLKFESGVHRVQRIPATEAGGRIHTSAATVAVLPEAEDVDIEIRDQDIRIDTMRAGGAGGQHVNKTDSAVRITHLPTGIIVVSAEKSQHQNRRLAMQVLRSRLFDLERERVDSQRSEARKSQVGSGDRSQRIRTYNFPQGRVTDHRINLTLHNIDRVMEGVGLDEIIDQLIAENQASLLAAMEGHGG
>NC_022997.1|WP_023786067.1|689569_690469_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MGADRGVPPFAGMTVRDAQAALGRALGGAGIEDPAREARLLVTAALGETAEGLLRNPALRFDAGAAETLSSFAERRLAREPVSRILGARGFFGREFKVTPATLDPRPCTETVVEAALAVVTAEGWRQRPVRILDVGTGSGALLVTLLAELPLAVGVGTDVSDEALRVAEENAVRLGVASRASFLNRRDLNDIAGPFDLMVSNPPYIPSGDIAALEPEVRVYDPAGALDGGADGLAIYRALARDLVPIVPEGWALFEVGAGQAADVEKLLRDGTGCALHEVRTWQDLGQHTRCVAVKTQY

Crispr_ID: NC_022997_4

• CRISPR_ID: NC_022997_4
• CRISPR_location: 756648-756861
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_022997_4

Consensus_repeat	Method
CCGAAAGGTGAGAAATTGGGCGG	PILER-CR

spacers of NC_022997_4

>4.1|756671|42|NC_022997|PILER-CR
ATCCCGGAGTCGCGACAGGGAGTCCAAGGAGTCGCGCCCTCC
>4.2|756736|39|NC_022997|PILER-CR
GCCGGATTCAAGCCAAGCGATTCCTTGGATTCGCGCACA
>4.3|756798|41|NC_022997|PILER-CR
ATCATAGAGTCGCGCGCGGATTTCCGCGGGTTTCGCTGCAT

CRISPR arrays and Neighbor proteins around NC_022997_4

CRISPR arrays

The CRISPR arrays of NC_022997_4

>merge|NC_022997|4|756648-756861|PILER-CR
CCCAAAGGTGAGAAAGTGGGCTGATCCCGGAGTCGCGACAGGGAGTCCAAGGAGTCGCGCCCTCCCCGAAAGGTGAGAAAATGGGCGGGCCGGATTCAAGCCAAGCGATTCCTTGGATTCGCGCACAGCTAAAGGTGAGAGATTGGGCGGATCATAGAGTCGCGCGCGGATTTCCGCGGGTTTCGCTGCATCTGAAAGGTGAGAAATTGGGCGG

>NC_022997|4|1|756648-756861|PILER-CR
CCCAAAGGTGAGAAAGTGGGCTG	ATCCCGGAGTCGCGACAGGGAGTCCAAGGAGTCGCGCCCTCC
CCGAAAGGTGAGAAAATGGGCGG	GCCGGATTCAAGCCAAGCGATTCCTTGGATTCGCGCACA
GCTAAAGGTGAGAGATTGGGCGG	ATCATAGAGTCGCGCGCGGATTTCCGCGGGTTTCGCTGCAT
CTGAAAGGTGAGAAATTGGGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_023786121.1|760360_760672_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NC_022997.1|WP_144083493.1|742680_745536_-|S-layer-family-protein	unknown	unknown	gnl|CDD|240612
NC_022997.1|WP_081717805.1|755550_755763_+|AlpA-family-phage-regulatory-protein	unknown	unknown	gnl|CDD|283558
NC_022997.1|WP_023786110.1|748919_752069_-|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	unknown	unknown	gnl|CDD|273608
NC_022997.1|WP_023786120.1|759008_760364_-|type-II-toxin-antitoxin-system-HipA-family-toxin	unknown	unknown	gnl|CDD|377920
NC_022997.1|WP_144083494.1|754741_755383_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786124.1|761960_762317_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786113.1|753331_754618_+|site-specific-integrase	unknown	unknown	gnl|CDD|271182
NC_022997.1|WP_023786128.1|765677_766184_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786125.1|762440_762617_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786127.1|765258_765591_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786126.1|762613_765064_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379210
NC_022997.1|WP_023786108.1|746644_747637_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
NC_022997.1|WP_023786119.1|758784_759012_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786123.1|761289_761958_+|ParA-family-protein	unknown	unknown	gnl|CDD|349760
NC_022997.1|WP_023786116.1|755848_756136_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_144083495.1|756930_757908_+|RepB-family-plasmid-replication-initiator-protein	unknown	unknown	gnl|CDD|376444
NC_022997.1|WP_041317270.1|747733_748822_+|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	unknown	unknown	gnl|CDD|185333
NC_022997.1|WP_081717615.1|740982_741747_-|thioredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|239321
NC_022997.1|WP_023786106.1|742045_742606_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_144083493.1|742680_745536_-|S-layer-family-protein	gnl|CDD|240612	cd12820, LbR_YadA-like, YadA-like, left-handed beta-roll. This group contains the collagen-binding domain virulence factor YadA an adhesion proteins of several Yersinia species, and related cell surface proteins, including Moraxella catarrhalis UspA-like proteins. The collagen-binding portion is found in the hydrophobic N-terminal region. YadA forms a matrix on the bacterial outer membrane, which mediates binding to collagen and epithelial cells. YadA inhibits the complement-activating pathway with the coating of the cell surface with factor H, which impedes C3b molecules. These domains form a left handed beta roll made up of a series of short repeated elements. UspA1 and UspA2 are part of a class of pathogenicity factors that act as cell surface adhesion molecules, in which N-terminal head and neck domains extend from the bacterial outer membrane. The UspA1 head domain of Moraxella catarrhalis, is formed from trimeric left-handed parallel beta-helices of 14-16 amino acid repeats. The UspA1 head domain connects to a neck region of large extended, charged loops that maybe be ligand binding, which is in turn connected to an extended coiled coil domain that tethers the head and neck region to the cell surface via a transmembrane region.	0.00052753
NC_022997.1|WP_081717805.1|755550_755763_+|AlpA-family-phage-regulatory-protein	gnl|CDD|283558	pfam05930, Phage_AlpA, Prophage CP4-57 regulatory protein (AlpA). This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant, overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins.	8.71448e-11
NC_022997.1|WP_023786110.1|748919_752069_-|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	gnl|CDD|273608	TIGR01414, Contains:_AIDA-I_translocator, outer membrane autotransporter barrel domain. A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	1.07045e-72
NC_022997.1|WP_023786120.1|759008_760364_-|type-II-toxin-antitoxin-system-HipA-family-toxin	gnl|CDD|377920	pfam07804, HipA_C, HipA-like C-terminal domain. The members of this family are similar to a region close to the C-terminus of the HipA protein expressed by various bacterial species. This protein is known to be involved in high-frequency persistence to the lethal effects of inhibition of either DNA or peptidoglycan synthesis. When expressed alone, it is toxic to bacterial cells, but it is usually tightly associated with HipB, and the HipA-HipB complex may be involved in autoregulation of the hip operon. The hip proteins may be involved in cell division control and may interact with cell division genes or their products.	2.00947e-55
NC_022997.1|WP_023786126.1|762613_765064_+|AAA-family-ATPase	gnl|CDD|379210	pfam13476, AAA_23, AAA domain.	6.79918e-11
NC_022997.1|WP_023786113.1|753331_754618_+|site-specific-integrase	gnl|CDD|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.12975e-42
NC_022997.1|WP_081717615.1|740982_741747_-|thioredoxin-domain-containing-protein	gnl|CDD|239321	cd03023, DsbA_Com1_like, DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC motif, assumed to be imbedded in a DsbA-like structure. Its homology to DsbA suggests that the protein is a protein disulfide oxidoreductase. The role of such a protein in pathogenesis is unknown.	2.82818e-46
NC_022997.1|WP_023786123.1|761289_761958_+|ParA-family-protein	gnl|CDD|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	2.67034e-29
NC_022997.1|WP_144083495.1|756930_757908_+|RepB-family-plasmid-replication-initiator-protein	gnl|CDD|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	5.6331e-28
NC_022997.1|WP_023786108.1|746644_747637_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	1.26394e-41
NC_022997.1|WP_041317270.1|747733_748822_+|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	gnl|CDD|185333	PRK15435, PRK15435, bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada.	1.60923e-139
NC_022997.1|WP_023786121.1|760360_760672_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	7.08847e-05

Protein sequences

>NC_022997.1|WP_023786116.1|755848_756136_+|hypothetical-protein
MPRFYEEAAHLLLIVLTHGVVLGVERNHLAVLYDFAGELDRVMAMRRSHADTAEILLDSMILWGFFDVPPDRRKRLLAIIGTFIGNLMTIRRPAA
>NC_022997.1|WP_081717805.1|755550_755763_+|AlpA-family-phage-regulatory-protein
MRTLTLKEVRSIVRYTPQHILRLEKAGKFPRRIRLGENRIGWLLTDIEDWLKARLPAQTYRADPEPADAL
>NC_022997.1|WP_144083494.1|754741_755383_+|hypothetical-protein
MAGPKRRESRKSPVREAPEELEIPQPPPLPTLPIGGPLRSSPVQRPDTKLLDTLLRHFADQQEDRRIWSAPTTQAEKAVSAIEDAHKLTLLERLDLRYALVRDLIDIFLSRCPIHEDSPNRAPELWSDREGRKENPAAFLRRVYARWYGRGMTRADIKLLDPPLYQALAVWMHRHPEETLADMHSPMQEIMRQIDEYYDRRRQSIAPRNRRRK
>NC_022997.1|WP_023786113.1|753331_754618_+|site-specific-integrase
MPTLKANHRVIKAARPVDGRRTRYRIDGLEGLWLDVSVTGKAYWYIRYQPGGRGTRTERWYRVGTRESVSLADAGQKARNVLTAAYANERDPHVERKVKRSETMRFADLYDDWHKRHASGLARVATDESTWQTHIKNGLGRQRLTDLRRGEIGKLRDRVAKTGGPIASNNVLVLINRILNWGVNEGVLEFNPAARLRKVGEVKPRERVLSPAEIPTFWRALEAMEGMTGEHMGKAEKGRMLSPATRSALRLMLLTGQRRTEVVEARKSELELDGNEPVWMIPGERTKNGLLHRVPLCSMACAEFKKAVAASSASSLYVFPSPVAAEDTPILASAVTRAMARLVGELKITKVSPHDLRRTVGTEMAKLGLPTHVRSLVLNHSAISRSITDAVYNRYAYDREKREALSAWEAELARLLSGTIRVAHCDAE
>NC_022997.1|WP_023786110.1|748919_752069_-|autotransporter-outer-membrane-beta-barrel-domain-containing-protein
MRISTDAGVCRNIALRLLSSAAIIPSVALVIGLQTARPAIAGSCTPGPTSVCSGAGSGADVTQNINLGSPVEITTTAGFGLDITDGGDGFSIVGLGGVTFTDNFASIITTNGSYGIFAENTVSGTLSIVSTGTLIATGGDGIRTYNDGADTLVRVHDTEGDGNGINVDHQGSGSVHIISTGQATGHTLNGIYGYVWSGTSMTVEAVDTQGAHEGIFARNGTSGALVVTSTGQATGTSGRGILADNIVGSTDVTVSAVNTHGGDMGIRVNHYGTGFLEVNSTGTASGGLSGLSTLGTASSTTATINAADTDGGGWGIYAIHEGAGPITVTSTGTAIGHGGAGIVVQTGTGSSGLNLTAHNARGGQHGIQTDHNSAAGTPGNTAAIVVTGHILGGTGYGITTASTAGVLTTIDVQAGALVESNSGNAIANDDGDSAIVIADGGTVNGRVSLGFGNDTITLRGSLSGITVLDGGGGGTDVLNLSDAAHVVHAGSAIQNWSAINLDNSRVTLTEGGVTVGTPGDMTTGIFLRNGSTLDGSQDNFSLNGNMSLAAGTQFIASGNGSGTNAISGNVVNAGLISAAGGGAGDRIRIAGDYAGNGGTIVLETRLGDDTSPTDKLEIAGGTSGTSTVRVTNANGPGAATNEGIEIIKIAGASHGVFALQGDYQFKGAPAIVGGAYAYRLEKGNASESETNNWYLRSELYDTTDPRYRPDASLYQPGASAYEAYPHALLGLNTLSTLQQRVGNRAWMNDSGLSHENQGGPAPSQSGSTARHAGVWARVEGARNRIDPHSATAGKRFDQTVFKAQAGVDGPVFQNSESTLQGGITAHYSQGVINTHSEHGDGRIATSGYGLGGTLTWYGYDGLYIDGQAQGTWYQSELSSLLASRTLAADNDAFGYTFSLESGHRASFGSGWSITPQAQLVYSNVDFDTFVDVFGAPVSLDRGASLQGRLGLTLAHETSWRDVNGQTSRAQTYGIANIYHEFLDGSRVDVADTRFHFKQDRVWGGLGAGSTYSWRDDAYSLYAEALVNTSLASVSESYSLQGKAGGRMRW
>NC_022997.1|WP_041317270.1|747733_748822_+|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada
MSPTVEQPPPQSPPASRREEAFWKALQERDRSFDGRFYYSVATTGVYCRPSCPARLAKRENVAFHVSCAAAEAAGFRPCKRCKPNEASLHDRYAAKVAAACRLIESAEDAPKLADLARVTGFSAFHFHRVFKGVTGVTPKAYGMAHRGKRVRESLTRAASVTDAIYEAGFNSSARFYANSTDVLGMTPSEFRTGGATAEMKFAVGACSLGSILVAASDKGITSIMLGDDPEALVHDLEDRFPRARLVGGDAAFEDVVAKVVGLVEAPDAGFDLPLDIRGTAFQHRVWQALREIPAGTTATYSEIAERIGMPKAVRAVAGACAANKIAVAIPCHRVVRNDGSLSGYRWGVARKRALIDRERKG
>NC_022997.1|WP_023786108.1|746644_747637_+|LLM-class-flavin-dependent-oxidoreductase
MRVDIAGIGREPDRMDHAAFVARMEEIDRLGYDGVWFNEFHFQTPPQPYPSLLLLAAAVLARTERVRVGTSVLVLPLHNPLVLAEQIAQLDWQSGGRIDIGLGRGTDPGTLARLGIDPASTRERFEDAFAAMRSVWLGTARQRAADGEALTIPVQPCVQAPHPPLYVAGYTEETLTFAGRHGLPLLLSLEPPETRQIEIYRDLVRAHGFPSRLAESSLTRYVVVGRSAADAEAHLEHLLPLLQTRRIYYAGRRGVAPGDVLPIDRELLLRDQLILGDPESCFAQIADLRRRMGIAALRCVFNGNGVLSPPLSMEQMRLFSQEVLPCLRDI
>NC_022997.1|WP_144083493.1|742680_745536_-|S-layer-family-protein
MNNLQDAVNSSATGDSNTLIRARQSSATGTLNSLNDAQNSSASGTSNQLSGTVNSSAAGDRNTISGSNNASASGEQNQILNGSHNASASGFNNQLNNAANSNAAGDRNAITNSNNASASGQQNQILNGSHNASASGVSNEISASQNATASGNDNTITGSHNASASGFNNQLNNAANSNAAGDRNAITNSINASASGQQNQILNGSHNASASGASNEISASENATASGNDNTITGSDNASASGQQNQITNGSHNASASGVSNEISASQNATASGNDNTITGSHNASASGVSNEIDNAQNASATGNDNTISDSINASASGQQNQILNGSHNASASGQQNQITNGSHNASASGFDNEIDNAQNSTAVGDGNTLDTATGSSVYGSGNSITFGTDSAAIGTDNALFGVAGSTATGSSNFLIGTDNVSATGASNILVGTANSSATGFFNIMALSENSSATGTGNIVAFSQNAFATGTLNVLLGASNSSTTGVLNILAGANNSSATGTFNLLTNATDSAAVGTGNNLTNATASSATGTANDLTDATSSGAVGNDNQLVAALQSFSVGASNILNDAENSSATGTANDLMTATNSNAVGQGNIGTNATNSSATGTNNNLTNATNSSATGQGNIAADATNSSATGTNNDLTQAENSSATGDGNLLSDATNSGAVGFRNNLTDATNSFAVGNPNNLAGATNSTAIGSTNSMVGAQQSLTVGTANNADGALNSLAVGSTSRVTGSTSAIAFGTNANASNANNSFAFGNNANASGTTNSLAAGANATVTANDGNAIGTNSQVAHARSTALGFGAQSEFADEVTLGAKNGSQTYTTPGITSDLSKQRQTGRLELVTTDANGHLASDGGDVFRSIAKLQAGVAVALAAEAPSLTSAENFGMRIGWGNFEGDANAVAVSAIGVVCRNCFSSGDRIAIDGSVGAGWSDYKSYSAGNSIGGRAGVQWTW
>NC_022997.1|WP_023786106.1|742045_742606_+|hypothetical-protein
MLRRGVAAVFLLLAMSVSGAAGTHIAEPAVPRDAGPAASSPLPDDTKLTLLIRTTLIALNQANATGNYSVLRDLAAPGFQAGNSQARLAEIFAALRGRNLDLSPILFFDPKLVQPPAIQPDGRLRITGFFDTRPERVIFDLMFETVEGDWRLFGIAIDVMPPEAPKADGAPPGADKNDADARKPSD
>NC_022997.1|WP_081717615.1|740982_741747_-|thioredoxin-domain-containing-protein
MSPAASTRALALVCASLLALDPAGLRSASAEPLPADRAGLDAYIRDYLMNNPEVVRDALLKLEQDEQIANTKRALIEHKDALYASGSPEIGNPDAKVTIVEFSDYNCPYCRATYPDLKSFLKDNPDTKVVLKNVASFGKDSEAVAHIVIAAAKQGNFEALHDALMTQKGQVTEERALDVAKGLGFDIDRIKKDAAATETAETLAATQNLANQLSVNVTPLYIVGHQGVAGAPDDLLAQLSAHAESVRKNGCEVC
>NC_022997.1|WP_144083495.1|756930_757908_+|RepB-family-plasmid-replication-initiator-protein
MRNAKGEIHFLTSHLSIRTLNAVSMRKISQLIDAGSFEVHEEAKLPSKLLATDMKVTGQPLDPAHMGRIIKPRELVDIIELTPLNRSETILYNQLLANAWNNINTQRIHKVLKASLRGSHQSNDRLEDAFDKLMAAWAKIRARDPQTGRMSTFRVHLIGTNKEEDREDGYFYYTFPPDLLAVIQQSKAWATIKTHIMYALRSKYSIRLYEMIERRIGMYKQHEEFTVDEFRAMLGVPAGKLERFAEFNKHCLKPALAEVNQLTDFYVDVLAVKRGRAVDKLMVAWHKKSVKELQAAFDERERSRVGREARQNRKLETIRFDDENS
>NC_022997.1|WP_023786119.1|758784_759012_+|hypothetical-protein
MASDPVLIAFAVRRATSSNKPVWTRIGCAYPHDTGAGLTVVLDALPTDGRIVLLERDFDDDERILRQARKRGALT
>NC_022997.1|WP_023786120.1|759008_760364_-|type-II-toxin-antitoxin-system-HipA-family-toxin
MKYVPTALLNVFLDGRKRRKVGRLATQARRILFEYDPDFLSSGLQISPFQLPARAGIVIAEPVPFDGLFGVFNDSLPDGWGRLLLDRAVERAGILRGSLTPLDRLAYVGRHGMGALSYEPDHSDSDGEPIVLTLDKLAADAATVLKGEQGAIVDKLLKLNGASAGARPKVVAQVSADKKKIIHGPASLPPGYAHWMIKFPSQLDEADVGPIEYAYSLMARAAGIDMPETHLFGAKKKRYFGIKRFDRDGDRRVHMHSLSGLLHADHRTPSLDYDAFLKATQVLTKDITQVEKAFRLACFNVLAHNRDDHAKNFSYLLDDETGQWSLAPAYDLIFSSGPAGEQSMMVMGEGRGPGVEHLRALAKKHGLKKGEAILDEVRSAIAKWPDVAADAGVSKKSASMITARIAPASSKPARSSKKPAAKTPPAAKKSAKPKKPPAAKKSKAAKTARKR
>NC_022997.1|WP_023786121.1|760360_760672_-|helix-turn-helix-transcriptional-regulator
MAVTLKSPADIQDALRARFRARRLVLNLTQEGLANRSGVTLATLRRFERTGLIAFDSLLKLALVLDCLGDFEKVAAEDERSLIGRPLDAVLAQKRGRRKGRIT
>NC_022997.1|WP_023786123.1|761289_761958_+|ParA-family-protein
MIITFASSKGGVGKSTTCACIASALAFDGARVLLLDLDQNRTLDRWARKAPIEGLTVTAIDPQKFGSFVREAEASGDYDHICIDLPGSREVTLFKALARSDLVVIPAQASEPDLREALVVVGDIRDVNETTSRTIPYRLLLTKVYPLRTRVTDFAYRELERLGLPLFRTALVERSAYREMFLNGQPPTKSEAGKGAGLEVTSLLAEIRAIVEGANEDIRKAG
>NC_022997.1|WP_023786124.1|761960_762317_+|hypothetical-protein
MKTERAPFAPITPDYDDKLERLAADKGVGALVKPVANRAGEGAATLAPQERPAPSPDATPRSDMKSLNLELPAYVWTELKIRAAQQQTSLKHVVMTALVKDGVTIKDADMIEDGRRLR
>NC_022997.1|WP_023786125.1|762440_762617_+|hypothetical-protein
MSSLQENIAAKFLESLAAIKEVDERNVERLRELLASGGKLKAEDFVKIFTTPADGEVK
>NC_022997.1|WP_023786126.1|762613_765064_+|AAA-family-ATPase
MIKLESAHIEEVRGIRKLDIDFKRKKFAVSGPNGSGKSGVIDAIEFGLTGDIGRLAGKGTKQLSIKEHGPHVDKVKFPNAAFVQLSVFFPGLNKSATITRSISAPQKPTIEPADADVLAAFKEVEEHPEITLSRREVLKFIITEPTTRSQDIQIILKLDGIGQTRSALNTAQNTLKKKQGQAESAKHERREVLVRHLNVKNFDAREVLEAVNLRREALDLPKISTLEADTKLDAGVAGGKAPEFNKQSALRDLKALDDVVAGLAAVGKKQASVILDGLGRLEADPGLLTMLHRRTLIEKGLSLVDGAECPLCDHEWDDEGQLRDHLRIKLAKSQEAGKLNDALLNAGGELSGETSRIAGLINPVTKIAAAEGEAETAAILSGWTKDLDQLRGSLETLDGITGLKDRLGKGWADMPPDLPKALQNLRAKLNAKPDQSARIDAQTFLTTAQARIADYRDASRVLVRSARAADAAKSAYDAYCRAMEDELNTLYQDVQEDFSSFYKIINEGDEEQFAAQLTPTEGRLDLLVNFYEKGLFPPAAFHSEGHQDGMGVCLYFALMKRLLGNRFTFALLDDVVMSVDVGHRYQFCKLLKEQFPDTQFVITTHDRLWAEQMRSAGVVSSKTSLVFQNWTVDTGPIVESDEEIWVDIDAALSKGKVPVAAAMVRHHLEYAVPHLAENLGARAVFRSDGAYELGDLLPSVLARMGELFGKAADAANSWSDAEARQAASDRKSKLSASNGASNVEQWAVNKAVHYNAWANFGKKDFQPVVAAFKDLMAQFRCEKCQSWLYITPKGSSPETLRCSCSAISMNLKGKPK
>NC_022997.1|WP_023786127.1|765258_765591_+|hypothetical-protein
MQGDIDQIPDITVHPDAEALLAYDHPGESLTNWQAVLTAKAWLGDDLGCFFVDGEQGAVRAVLVFRADRAFQAEAGSMDMRSAPIGQLFVLEVVCGARRTPSVLKADPVR
>NC_022997.1|WP_023786128.1|765677_766184_+|hypothetical-protein
MIMSAHSLKYTTHEGVTKLVPLDTIRLIRPMADEDKERAKESLKEKRGIDIDAARVNIRIEFGDKSSKLAQESLDAIKGQGVALVNLGSDRYVPAANITGAEAFTKEDADRLKGEDYTLKQTFRSKVETKAGTVLSSATPVQIMERRAKAMDGVPANSSNRKPVAKPA

Crispr_ID: NC_022997_5

• CRISPR_ID: NC_022997_5
• CRISPR_location: 1447293-1449615
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 34 spacers
• Cas_protein_info: cas2,cas1,cas4,cas7b,cas8c,cas5,cas3

Consensus repeat of NC_022997_5

Consensus_repeat	Method
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CRISPRCasFinder
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CRT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGACT	PILER-CR
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	PILER-CR
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	PILER-CR
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CRT

spacers of NC_022997_5

>5.1|1447325|34|NC_022997|CRISPRCasFinder,CRT
TAATGCCCCCCACAAAGCGGCGGCCATGCTCAAT
>5.2|1447391|35|NC_022997|CRISPRCasFinder,CRT
TCGCCGGTCCAGCGCGTGTTTTCGCGCACGATGGT
>5.3|1447458|23|NC_022997|CRISPRCasFinder,CRT
CATGGCGTTGCGGACAGGCCGAT
>5.4|1447513|35|NC_022997|CRISPRCasFinder,CRT
ACTCCAATGTGATCACCATCTGCAATCGGCATGCG
>5.5|1447580|35|NC_022997|CRISPRCasFinder,CRT
TGCGGATACCCGATCCCCTCGGAGCGGATGTTCTC
>5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT
TGTCCGTCCGGCGCGTTGAGGTCGCAGATGAT
>5.7|1447711|35|NC_022997|CRISPRCasFinder,CRT
TCGCATGGGTGCACGCACGGTGCCTGCGGGATCGA
>5.8|1447778|50|NC_022997|CRISPRCasFinder,CRT,PILER-CR
CGCTCCTTGCGGTTCAGCATGGCGTTTTCATGGCGTTTTTTCCCTTGCTG
>5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR
CTGCGCCGCAGGCTGCCGGCGAGGCCGATGTGGA
>5.10|1447926|30|NC_022997|CRISPRCasFinder,CRT
CGGGTTCCACGTCACGCTGCTCGCCACAGA
>5.11|1447988|33|NC_022997|CRISPRCasFinder,CRT
TGACGTTTGCGTCGCTAGTCCGCTCGACGATGT
>5.12|1448053|34|NC_022997|CRISPRCasFinder,CRT
CGAGGGGCAAAACCCCGTGGGCGAAGGAGCTTGA
>5.13|1448119|79|NC_022997|CRISPRCasFinder
CCTTTTCAGTTGGGTTTCTATCCACGCCTCCGCGCGGGAGGCGACGCGTCGCTCATCGTATGAGCCACAGCAGGGCGGC
>5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT
AGACCGTGGGGCAGATGCTCGAAGCCGTCTGGGA
>5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT
TGGGGTGATATTCGGCATGGCCGGATCGGGCGGC
>5.16|1448362|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT
ACGATCGGGAGCGCTGACCGGAGCTAACAGCTGC
>5.17|1448428|35|NC_022997|CRISPRCasFinder,PILER-CR,CRT
CCGGAGATTTACAACGACCTCGACGAAGATGTCGT
>5.18|1448495|32|NC_022997|CRISPRCasFinder,CRT
ACGGCCTCCGGGGAGGGATGGAGGATGTGGGA
>5.19|1448559|35|NC_022997|CRISPRCasFinder,CRT
CAGATCGCGGGCACAGATGACAAGCTGAGGGCGAA
>5.20|1448626|35|NC_022997|CRISPRCasFinder,CRT
CGGCTGCTCCTGATCGACACCGACACGTTCTTCAC
>5.21|1448693|33|NC_022997|CRISPRCasFinder,CRT
GCCGGGCCAAACCCCACCCGGATACATTCAGCG
>5.22|1448758|34|NC_022997|CRISPRCasFinder,CRT
CCTTCGCGAACAGCACCGTCCCGAACGTTGCGAT
>5.23|1448824|34|NC_022997|CRISPRCasFinder,CRT
CAGCAGCTCATGCCGCGCGGCGCACTCGTGCAAA
>5.24|1448890|33|NC_022997|CRISPRCasFinder,CRT
GGACGCATCTGCTGAACAGACTGCCGGGATTGA
>5.25|1448955|34|NC_022997|CRISPRCasFinder,CRT
TTGATGGTCTCAGGCAGGTCGGCGCGCGAGATAT
>5.26|1449021|34|NC_022997|CRISPRCasFinder,CRT
TTTACGTCTTCGGCGGTGACGATGCGGACCCGGC
>5.27|1449087|34|NC_022997|CRISPRCasFinder,CRT
AAGAGTGCAACCTTTACGGTGTTTCCTCGCCAAT
>5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT
AGGGCGCCTATTACGCCAAGTCGCTGACGGACGC
>5.29|1449219|34|NC_022997|CRISPRCasFinder,CRT
CAGAACTCCGCGTCATCGTCATTCGCCTCAGCGA
>5.30|1449285|34|NC_022997|CRISPRCasFinder,CRT
GCGGCCACCATTGCGCTTGATGCAAATCACCGCG
>5.31|1449351|35|NC_022997|CRISPRCasFinder,CRT
GGGCATGACTCGTTCATCCCGACAGATATTGTGCT
>5.32|1449418|34|NC_022997|CRISPRCasFinder,CRT
GCCAGCGTTAGGCCTTGCTCCACCGCGCACTTTT
>5.33|1449484|34|NC_022997|CRISPRCasFinder,CRT
CTGTGATCGCGGAGAAGCAGGAACAGGTGATCGC
>5.34|1449550|34|NC_022997|CRISPRCasFinder,CRT
TGAGCGTTGACGTTTCGGTCGGCATGGCAACGGA
>5.35|1447514|34|NC_022997|PILER-CR
CTCCAATGTGATCACCATCTGCAATCGGCATGCG
>5.36|1447581|34|NC_022997|PILER-CR
GCGGATACCCGATCCCCTCGGAGCGGATGTTCTC
>5.37|1447648|31|NC_022997|PILER-CR
GTCCGTCCGGCGCGTTGAGGTCGCAGATGAT
>5.38|1447926|41|NC_022997|PILER-CR
GAGGCGACCTTCGGGTTCCACGTCACGCTGCTCGCCACAGA
>5.39|1447999|33|NC_022997|PILER-CR
TGACGTTTGCGTCGCTAGTCCGCTCGACGATGT
>5.40|1448164|34|NC_022997|PILER-CR,CRT
GCGTCGCTCATCGTATGAGCCACAGCAGGGCGGC
>5.41|1448495|40|NC_022997|PILER-CR
AGGCGACCACGGCCTCCGGGGAGGGATGGAGGATGTGGGA
>5.42|1448567|35|NC_022997|PILER-CR
CAGATCGCGGGCACAGATGACAAGCTGAGGGCGAA
>5.43|1448634|35|NC_022997|PILER-CR
CGGCTGCTCCTGATCGACACCGACACGTTCTTCAC
>5.44|1448701|33|NC_022997|PILER-CR
GCCGGGCCAAACCCCACCCGGATACATTCAGCG
>5.45|1448766|34|NC_022997|PILER-CR
CCTTCGCGAACAGCACCGTCCCGAACGTTGCGAT
>5.46|1448832|34|NC_022997|PILER-CR
CAGCAGCTCATGCCGCGCGGCGCACTCGTGCAAA
>5.47|1448898|33|NC_022997|PILER-CR
GGACGCATCTGCTGAACAGACTGCCGGGATTGA
>5.48|1448963|34|NC_022997|PILER-CR
TTGATGGTCTCAGGCAGGTCGGCGCGCGAGATAT
>5.49|1449029|34|NC_022997|PILER-CR
TTTACGTCTTCGGCGGTGACGATGCGGACCCGGC
>5.50|1449095|34|NC_022997|PILER-CR
AAGAGTGCAACCTTTACGGTGTTTCCTCGCCAAT
>5.51|1449161|34|NC_022997|PILER-CR
AGGGCGCCTATTACGCCAAGTCGCTGACGGACGC
>5.52|1449227|34|NC_022997|PILER-CR
CAGAACTCCGCGTCATCGTCATTCGCCTCAGCGA
>5.53|1449293|34|NC_022997|PILER-CR
GCGGCCACCATTGCGCTTGATGCAAATCACCGCG
>5.54|1449359|35|NC_022997|PILER-CR
GGGCATGACTCGTTCATCCCGACAGATATTGTGCT
>5.55|1449426|34|NC_022997|PILER-CR
GCCAGCGTTAGGCCTTGCTCCACCGCGCACTTTT
>5.56|1449492|34|NC_022997|PILER-CR
CTGTGATCGCGGAGAAGCAGGAACAGGTGATCGC
>5.57|1449558|34|NC_022997|PILER-CR
TGAGCGTTGACGTTTCGGTCGGCATGGCAACGGA

CRISPR arrays and Neighbor proteins around NC_022997_5

CRISPR arrays

The CRISPR arrays of NC_022997_5

>merge|NC_022997|5|1447293-1449615|CRISPRCasFinder,CRT,PILER-CR,PILER-CR,PILER-CR,CRT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGACTAATGCCCCCCACAAAGCGGCGGCCATGCTCAATGTTTCTATCCACGCCTCTGCGCGGGAGGCGACTCGCCGGTCCAGCGCGTGTTTTCGCGCACGATGGTGTTTCTATCCACGCCTCCGCGCGGGAGGCGACCATGGCGTTGCGGACAGGCCGATGTTTCTATCCACGCCTCCGCGCGGAAGGCGACACTCCAATGTGATCACCATCTGCAATCGGCATGCGGTTTCTATCCACGCCTCCGCGCGGGAGGCGACTGCGGATACCCGATCCCCTCGGAGCGGATGTTCTCGTTTCTATCCACGCCTCCGCGCAGGAGGCGACTGTCCGTCCGGCGCGTTGAGGTCGCAGATGATGTTTCTATCCACGCCTCCGTGCGGGAGGTGACTCGCATGGGTGCACGCACGGTGCCTGCGGGATCGAGTTTCTATCCACGCCTCCGCGCGGGAGGCGACCGCTCCTTGCGGTTCAGCATGGCGTTTTCATGGCGTTTTTTCCCTTGCTGTTTTCTATCCACGCCTCCGCGCGGGAGGCGACCTGCGCCGCAGGCTGCCGGCGAGGCCGATGTGGAGTTTCTATCCACGCCTCCGCGGAGGCGACCTTCGGGTTCCACGTCACGCTGCTCGCCACAGAGTTTCTATCCACGCCTCCGCGCGGGAGGCGACTGACGTTTGCGTCGCTAGTCCGCTCGACGATGTGTTTCTATCCACGCCTCCGCGCGGGAGGCGACCGAGGGGCAAAACCCCGTGGGCGAAGGAGCTTGAGTTTCTATCCACGCCTCCGGGAAACGGAACAACCTTTTCAGTTGGGTTTCTATCCACGCCTCCGCGCGGGAGGCGACGCGTCGCTCATCGTATGAGCCACAGCAGGGCGGCGTTTCTATCCACGCCTCCGCGTGGGAGGCGACAGACCGTGGGGCAGATGCTCGAAGCCGTCTGGGAGTTTCTATCCACGCCTCCGCGCGGGAGGCGACTGGGGTGATATTCGGCATGGCCGGATCGGGCGGCGTTTCTATCCACGCCTCCGCGCGGGAGGCGACACGATCGGGAGCGCTGACCGGAGCTAACAGCTGCGTTTCTATCCACGCCTCCGCGCGGGAGGCGACCCGGAGATTTACAACGACCTCGACGAAGATGTCGTGTTTCTATCCACGCCTCCGCGCGGAGGCGACCACGGCCTCCGGGGAGGGATGGAGGATGTGGGAGTTTCTATCCACGCCTCCGCGCGGGAGGCGACCAGATCGCGGGCACAGATGACAAGCTGAGGGCGAAGTTTCTATCCACGCCTCCGCGCGGGAGGCGACCGGCTGCTCCTGATCGACACCGACACGTTCTTCACGTTTCTATCCACGCCTCCGCGCGGGAGGCGACGCCGGGCCAAACCCCACCCGGATACATTCAGCGGTTTCTATCCACGCCTCCGCGCGGGAGGCGACCCTTCGCGAACAGCACCGTCCCGAACGTTGCGATGTTTCTATCCACGCCTCCGCGCGGGAGGCGACCAGCAGCTCATGCCGCGCGGCGCACTCGTGCAAAGTTTCTATCCACGCCTCCGCGCGGGAGGCGACGGACGCATCTGCTGAACAGACTGCCGGGATTGAGTTTCTATCCACGCCTCCGCGCGGGAGGCGACTTGATGGTCTCAGGCAGGTCGGCGCGCGAGATATGTTTCTATCCACGCCTCCGCGCGGGAGGCGACTTTACGTCTTCGGCGGTGACGATGCGGACCCGGCGTTTCTATCCACGCCTCCGCGCGGGAGGCGACAAGAGTGCAACCTTTACGGTGTTTCCTCGCCAATGTTTCTATCCACGCCTCCGCGCGGGAGGCGACAGGGCGCCTATTACGCCAAGTCGCTGACGGACGCGTTTCTATCCACGCCTCCGCGCGGGAGGCGACCAGAACTCCGCGTCATCGTCATTCGCCTCAGCGAGTTTCTATCCACGCCTCCGCGCGGGAGGCGACGCGGCCACCATTGCGCTTGATGCAAATCACCGCGGTTTCTATCCACGCCTCCGCGCGGGAGGCGACGGGCATGACTCGTTCATCCCGACAGATATTGTGCTGTTTCTATCCACGCCTCCGCGCGGGAGGCGACGCCAGCGTTAGGCCTTGCTCCACCGCGCACTTTTGTTTCTATCCACGCCTCCGCGCGGGAGGCGACCTGTGATCGCGGAGAAGCAGGAACAGGTGATCGCGTTTCTATCCACGCCTCCGCGCGGGAGGCGACTGAGCGTTGACGTTTCGGTCGGCATGGCAACGGAGTTTCTATCCACGCCTCCGCGCGGGAGGCGAC

>NC_022997|5|4|1447293-1449615|CRISPRCasFinder
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TAATGCCCCCCACAAAGCGGCGGCCATGCTCAAT
GTTTCTATCCACGCCTCTGCGCGGGAGGCGAC	TCGCCGGTCCAGCGCGTGTTTTCGCGCACGATGGT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CATGGCGTTGCGGACAGGCCGAT
GTTTCTATCCACGCCTCCGCGCGGAAGGCGAC	ACTCCAATGTGATCACCATCTGCAATCGGCATGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGCGGATACCCGATCCCCTCGGAGCGGATGTTCTC
GTTTCTATCCACGCCTCCGCGCAGGAGGCGAC	TGTCCGTCCGGCGCGTTGAGGTCGCAGATGAT
GTTTCTATCCACGCCTCCGTGCGGGAGGTGAC	TCGCATGGGTGCACGCACGGTGCCTGCGGGATCGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGCTCCTTGCGGTTCAGCATGGCGTTTTCATGGCGTTTTTTCCCTTGCTG
TTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CTGCGCCGCAGGCTGCCGGCGAGGCCGATGTGGA
GTTTCTATCCACGCCTCCGCGGAGGCGACCTT	CGGGTTCCACGTCACGCTGCTCGCCACAGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGACGTTTGCGTCGCTAGTCCGCTCGACGATGT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGAGGGGCAAAACCCCGTGGGCGAAGGAGCTTGA
GTTTCTATCCACGCCTCCGGGAAACGGAACAA	CCTTTTCAGTTGGGTTTCTATCCACGCCTCCGCGCGGGAGGCGACGCGTCGCTCATCGTATGAGCCACAGCAGGGCGGC
GTTTCTATCCACGCCTCCGCGTGGGAGGCGAC	AGACCGTGGGGCAGATGCTCGAAGCCGTCTGGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGGGGTGATATTCGGCATGGCCGGATCGGGCGGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	ACGATCGGGAGCGCTGACCGGAGCTAACAGCTGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CCGGAGATTTACAACGACCTCGACGAAGATGTCGT
GTTTCTATCCACGCCTCCGCGCGGAGGCGACC	ACGGCCTCCGGGGAGGGATGGAGGATGTGGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CAGATCGCGGGCACAGATGACAAGCTGAGGGCGAA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGGCTGCTCCTGATCGACACCGACACGTTCTTCAC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCCGGGCCAAACCCCACCCGGATACATTCAGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CCTTCGCGAACAGCACCGTCCCGAACGTTGCGAT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CAGCAGCTCATGCCGCGCGGCGCACTCGTGCAAA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GGACGCATCTGCTGAACAGACTGCCGGGATTGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TTGATGGTCTCAGGCAGGTCGGCGCGCGAGATAT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TTTACGTCTTCGGCGGTGACGATGCGGACCCGGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	AAGAGTGCAACCTTTACGGTGTTTCCTCGCCAAT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	AGGGCGCCTATTACGCCAAGTCGCTGACGGACGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CAGAACTCCGCGTCATCGTCATTCGCCTCAGCGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCGGCCACCATTGCGCTTGATGCAAATCACCGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GGGCATGACTCGTTCATCCCGACAGATATTGTGCT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCCAGCGTTAGGCCTTGCTCCACCGCGCACTTTT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CTGTGATCGCGGAGAAGCAGGAACAGGTGATCGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGAGCGTTGACGTTTCGGTCGGCATGGCAACGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC

>NC_022997|5|1|1447293-1448118|CRT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TAATGCCCCCCACAAAGCGGCGGCCATGCTCAAT
GTTTCTATCCACGCCTCTGCGCGGGAGGCGAC	TCGCCGGTCCAGCGCGTGTTTTCGCGCACGATGGT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CATGGCGTTGCGGACAGGCCGAT
GTTTCTATCCACGCCTCCGCGCGGAAGGCGAC	ACTCCAATGTGATCACCATCTGCAATCGGCATGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGCGGATACCCGATCCCCTCGGAGCGGATGTTCTC
GTTTCTATCCACGCCTCCGCGCAGGAGGCGAC	TGTCCGTCCGGCGCGTTGAGGTCGCAGATGAT
GTTTCTATCCACGCCTCCGTGCGGGAGGTGAC	TCGCATGGGTGCACGCACGGTGCCTGCGGGATCGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGCTCCTTGCGGTTCAGCATGGCGTTTTCATGGCGTTTTTTCCCTTGCTG
TTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CTGCGCCGCAGGCTGCCGGCGAGGCCGATGTGGA
GTTTCTATCCACGCCTCCGCGGAGGCGACCTT	CGGGTTCCACGTCACGCTGCTCGCCACAGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGACGTTTGCGTCGCTAGTCCGCTCGACGATGT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGAGGGGCAAAACCCCGTGGGCGAAGGAGCTTGA
GTTTCTATCCACGCCTCCGGGAAACGGAACAACCTTTTCAGTTGGGTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCGTCGCTCATCGTATGAGCCACAGCAGGGCGGC
GTTTCTATCCACGCCTCCGCGTGGGAGGCGAC	AGACCGTGGGGCAGATGCTCGAAGCCGTCTGGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGGGGTGATATTCGGCATGGCCGGATCGGGCGGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	ACGATCGGGAGCGCTGACCGGAGCTAACAGCTGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CCGGAGATTTACAACGACCTCGACGAAGATGTCGT
GTTTCTATCCACGCCTCCGCGCGGAGGCGACC	ACGGCCTCCGGGGAGGGATGGAGGATGTGGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CAGATCGCGGGCACAGATGACAAGCTGAGGGCGAA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGGCTGCTCCTGATCGACACCGACACGTTCTTCAC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCCGGGCCAAACCCCACCCGGATACATTCAGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CCTTCGCGAACAGCACCGTCCCGAACGTTGCGAT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CAGCAGCTCATGCCGCGCGGCGCACTCGTGCAAA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GGACGCATCTGCTGAACAGACTGCCGGGATTGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TTGATGGTCTCAGGCAGGTCGGCGCGCGAGATAT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TTTACGTCTTCGGCGGTGACGATGCGGACCCGGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	AAGAGTGCAACCTTTACGGTGTTTCCTCGCCAAT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	AGGGCGCCTATTACGCCAAGTCGCTGACGGACGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CAGAACTCCGCGTCATCGTCATTCGCCTCAGCGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCGGCCACCATTGCGCTTGATGCAAATCACCGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GGGCATGACTCGTTCATCCCGACAGATATTGTGCT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCCAGCGTTAGGCCTTGCTCCACCGCGCACTTTT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CTGTGATCGCGGAGAAGCAGGAACAGGTGATCGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGAGCGTTGACGTTTCGGTCGGCATGGCAACGGA


>NC_022997|5|2|1447481-1447711|PILER-CR
GTTTCTATCCACGCCTCCGCGCGGAAGGCGACA	CTCCAATGTGATCACCATCTGCAATCGGCATGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGACT	GCGGATACCCGATCCCCTCGGAGCGGATGTTCTC
GTTTCTATCCACGCCTCCGCGCAGGAGGCGACT	GTCCGTCCGGCGCGTTGAGGTCGCAGATGAT
GTTTCTATCCACGCCTCCGTGCGGGAGGTGACTCGCATGGGTGCACGCACGGTGCCTGCGGGATCGAGTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGCTCCTTGCGGTTCAGCATGGCGTTTTCATGGCGTTTTTTCCCTTGCTG
TTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CTGCGCCGCAGGCTGCCGGCGAGGCCGATGTGGA
GTTTCTATCCACGCCTCCGCGGAGGCGACCTT	CGGGTTCCACGTCACGCTGCTCGCCACAGAGTTTCTATCCA
CGCCTCCGCGCGGGAGGCGACTGACGTTTGCG	TCGCTAGTCCGCTCGACGATGTGTTTCTATCCA
CGCCTCCGCGCGGGAGGCGACCGAGGGGCAAAACCCCGTGGGCGAAGGAGCTTGAGTTTCTATCCACGCCTCCGGGAAACGGAACAACCTTTTCAGTTGGGTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCGTCGCTCATCGTATGAGCCACAGCAGGGCGGC
GTTTCTATCCACGCCTCCGCGTGGGAGGCGAC	AGACCGTGGGGCAGATGCTCGAAGCCGTCTGGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGGGGTGATATTCGGCATGGCCGGATCGGGCGGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	ACGATCGGGAGCGCTGACCGGAGCTAACAGCTGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CCGGAGATTTACAACGACCTCGACGAAGATGTCGT
GTTTCTATCCACGCCTCCGCGCGGAGGCGACC	ACGGCCTCCGGGGAGGGATGGAGGATGTGGGAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCAGATCGC	GGGCACAGATGACAAGCTGAGGGCGAAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCGGCTGCT	CCTGATCGACACCGACACGTTCTTCACGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGCCGGGCC	AAACCCCACCCGGATACATTCAGCGGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCCTTCGCG	AACAGCACCGTCCCGAACGTTGCGATGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCAGCAGCT	CATGCCGCGCGGCGCACTCGTGCAAAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGGACGCAT	CTGCTGAACAGACTGCCGGGATTGAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACTTGATGGT	CTCAGGCAGGTCGGCGCGCGAGATATGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACTTTACGTC	TTCGGCGGTGACGATGCGGACCCGGCGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACAAGAGTGC	AACCTTTACGGTGTTTCCTCGCCAATGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACAGGGCGCC	TATTACGCCAAGTCGCTGACGGACGCGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCAGAACTC	CGCGTCATCGTCATTCGCCTCAGCGAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGCGGCCAC	CATTGCGCTTGATGCAAATCACCGCGGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGGGCATGA	CTCGTTCATCCCGACAGATATTGTGCTGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGCCAGCGT	TAGGCCTTGCTCCACCGCGCACTTTTGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCTGTGATC	GCGGAGAAGCAGGAACAGGTGATCGCGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACTGAGCGTT	GACGTTTCGGTCGGCATGGCAACGGAGTTTCTAT


>NC_022997|5|3|1447746-1448052|PILER-CR
	CTCCAATGTGATCACCATCTGCAATCGGCATGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGACT	GCGGATACCCGATCCCCTCGGAGCGGATGTTCTC
GTTTCTATCCACGCCTCCGCGCAGGAGGCGACT	GTCCGTCCGGCGCGTTGAGGTCGCAGATGAT
GTTTCTATCCACGCCTCCGTGCGGGAGGTGACTCGCATGGGTGCACGCACGGTGCCTGCGGGATCGAGTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGCTCCTTGCGGTTCAGCATGGCGTTTTCATGGCGTTTTTTCCCTTGCTG
TTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CTGCGCCGCAGGCTGCCGGCGAGGCCGATGTGGA
GTTTCTATCCACGCCTCCGCGGAGGCGACCTT	CGGGTTCCACGTCACGCTGCTCGCCACAGAGTTTCTATCCA
CGCCTCCGCGCGGGAGGCGACTGACGTTTGCG	TCGCTAGTCCGCTCGACGATGTGTTTCTATCCA
CGCCTCCGCGCGGGAGGCGACCGAGGGGCAAAACCCCGTGGGCGAAGGAGCTTGAGTTTCTATCCACGCCTCCGGGAAACGGAACAACCTTTTCAGTTGGGTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCGTCGCTCATCGTATGAGCCACAGCAGGGCGGC
GTTTCTATCCACGCCTCCGCGTGGGAGGCGAC	AGACCGTGGGGCAGATGCTCGAAGCCGTCTGGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGGGGTGATATTCGGCATGGCCGGATCGGGCGGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	ACGATCGGGAGCGCTGACCGGAGCTAACAGCTGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CCGGAGATTTACAACGACCTCGACGAAGATGTCGT
GTTTCTATCCACGCCTCCGCGCGGAGGCGACC	ACGGCCTCCGGGGAGGGATGGAGGATGTGGGAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCAGATCGC	GGGCACAGATGACAAGCTGAGGGCGAAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCGGCTGCT	CCTGATCGACACCGACACGTTCTTCACGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGCCGGGCC	AAACCCCACCCGGATACATTCAGCGGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCCTTCGCG	AACAGCACCGTCCCGAACGTTGCGATGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCAGCAGCT	CATGCCGCGCGGCGCACTCGTGCAAAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGGACGCAT	CTGCTGAACAGACTGCCGGGATTGAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACTTGATGGT	CTCAGGCAGGTCGGCGCGCGAGATATGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACTTTACGTC	TTCGGCGGTGACGATGCGGACCCGGCGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACAAGAGTGC	AACCTTTACGGTGTTTCCTCGCCAATGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACAGGGCGCC	TATTACGCCAAGTCGCTGACGGACGCGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCAGAACTC	CGCGTCATCGTCATTCGCCTCAGCGAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGCGGCCAC	CATTGCGCTTGATGCAAATCACCGCGGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGGGCATGA	CTCGTTCATCCCGACAGATATTGTGCTGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGCCAGCGT	TAGGCCTTGCTCCACCGCGCACTTTTGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCTGTGATC	GCGGAGAAGCAGGAACAGGTGATCGCGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACTGAGCGTT	GACGTTTCGGTCGGCATGGCAACGGAGTTTCTAT


>NC_022997|5|4|1448132-1449615|PILER-CR
	CTCCAATGTGATCACCATCTGCAATCGGCATGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGACT	GCGGATACCCGATCCCCTCGGAGCGGATGTTCTC
GTTTCTATCCACGCCTCCGCGCAGGAGGCGACT	GTCCGTCCGGCGCGTTGAGGTCGCAGATGAT
GTTTCTATCCACGCCTCCGTGCGGGAGGTGACTCGCATGGGTGCACGCACGGTGCCTGCGGGATCGAGTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGCTCCTTGCGGTTCAGCATGGCGTTTTCATGGCGTTTTTTCCCTTGCTG
TTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CTGCGCCGCAGGCTGCCGGCGAGGCCGATGTGGA
GTTTCTATCCACGCCTCCGCGGAGGCGACCTT	CGGGTTCCACGTCACGCTGCTCGCCACAGAGTTTCTATCCA
CGCCTCCGCGCGGGAGGCGACTGACGTTTGCG	TCGCTAGTCCGCTCGACGATGTGTTTCTATCCA
CGCCTCCGCGCGGGAGGCGACCGAGGGGCAAAACCCCGTGGGCGAAGGAGCTTGAGTTTCTATCCACGCCTCCGGGAAACGGAACAACCTTTTCAGTTGGGTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCGTCGCTCATCGTATGAGCCACAGCAGGGCGGC
GTTTCTATCCACGCCTCCGCGTGGGAGGCGAC	AGACCGTGGGGCAGATGCTCGAAGCCGTCTGGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGGGGTGATATTCGGCATGGCCGGATCGGGCGGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	ACGATCGGGAGCGCTGACCGGAGCTAACAGCTGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CCGGAGATTTACAACGACCTCGACGAAGATGTCGT
GTTTCTATCCACGCCTCCGCGCGGAGGCGACC	ACGGCCTCCGGGGAGGGATGGAGGATGTGGGAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCAGATCGC	GGGCACAGATGACAAGCTGAGGGCGAAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCGGCTGCT	CCTGATCGACACCGACACGTTCTTCACGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGCCGGGCC	AAACCCCACCCGGATACATTCAGCGGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCCTTCGCG	AACAGCACCGTCCCGAACGTTGCGATGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCAGCAGCT	CATGCCGCGCGGCGCACTCGTGCAAAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGGACGCAT	CTGCTGAACAGACTGCCGGGATTGAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACTTGATGGT	CTCAGGCAGGTCGGCGCGCGAGATATGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACTTTACGTC	TTCGGCGGTGACGATGCGGACCCGGCGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACAAGAGTGC	AACCTTTACGGTGTTTCCTCGCCAATGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACAGGGCGCC	TATTACGCCAAGTCGCTGACGGACGCGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCAGAACTC	CGCGTCATCGTCATTCGCCTCAGCGAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGCGGCCAC	CATTGCGCTTGATGCAAATCACCGCGGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGGGCATGA	CTCGTTCATCCCGACAGATATTGTGCTGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACGCCAGCGT	TAGGCCTTGCTCCACCGCGCACTTTTGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACCTGTGATC	GCGGAGAAGCAGGAACAGGTGATCGCGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGACTGAGCGTT	GACGTTTCGGTCGGCATGGCAACGGAGTTTCTAT
CCACGCCTCCGCGCGGGAGGCGAC

>NC_022997|5|2|1448132-1449615|CRT
	TAATGCCCCCCACAAAGCGGCGGCCATGCTCAAT
GTTTCTATCCACGCCTCTGCGCGGGAGGCGAC	TCGCCGGTCCAGCGCGTGTTTTCGCGCACGATGGT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CATGGCGTTGCGGACAGGCCGAT
GTTTCTATCCACGCCTCCGCGCGGAAGGCGAC	ACTCCAATGTGATCACCATCTGCAATCGGCATGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGCGGATACCCGATCCCCTCGGAGCGGATGTTCTC
GTTTCTATCCACGCCTCCGCGCAGGAGGCGAC	TGTCCGTCCGGCGCGTTGAGGTCGCAGATGAT
GTTTCTATCCACGCCTCCGTGCGGGAGGTGAC	TCGCATGGGTGCACGCACGGTGCCTGCGGGATCGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGCTCCTTGCGGTTCAGCATGGCGTTTTCATGGCGTTTTTTCCCTTGCTG
TTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CTGCGCCGCAGGCTGCCGGCGAGGCCGATGTGGA
GTTTCTATCCACGCCTCCGCGGAGGCGACCTT	CGGGTTCCACGTCACGCTGCTCGCCACAGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGACGTTTGCGTCGCTAGTCCGCTCGACGATGT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGAGGGGCAAAACCCCGTGGGCGAAGGAGCTTGA
GTTTCTATCCACGCCTCCGGGAAACGGAACAACCTTTTCAGTTGGGTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCGTCGCTCATCGTATGAGCCACAGCAGGGCGGC
GTTTCTATCCACGCCTCCGCGTGGGAGGCGAC	AGACCGTGGGGCAGATGCTCGAAGCCGTCTGGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGGGGTGATATTCGGCATGGCCGGATCGGGCGGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	ACGATCGGGAGCGCTGACCGGAGCTAACAGCTGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CCGGAGATTTACAACGACCTCGACGAAGATGTCGT
GTTTCTATCCACGCCTCCGCGCGGAGGCGACC	ACGGCCTCCGGGGAGGGATGGAGGATGTGGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CAGATCGCGGGCACAGATGACAAGCTGAGGGCGAA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CGGCTGCTCCTGATCGACACCGACACGTTCTTCAC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCCGGGCCAAACCCCACCCGGATACATTCAGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CCTTCGCGAACAGCACCGTCCCGAACGTTGCGAT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CAGCAGCTCATGCCGCGCGGCGCACTCGTGCAAA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GGACGCATCTGCTGAACAGACTGCCGGGATTGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TTGATGGTCTCAGGCAGGTCGGCGCGCGAGATAT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TTTACGTCTTCGGCGGTGACGATGCGGACCCGGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	AAGAGTGCAACCTTTACGGTGTTTCCTCGCCAAT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	AGGGCGCCTATTACGCCAAGTCGCTGACGGACGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CAGAACTCCGCGTCATCGTCATTCGCCTCAGCGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCGGCCACCATTGCGCTTGATGCAAATCACCGCG
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GGGCATGACTCGTTCATCCCGACAGATATTGTGCT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	GCCAGCGTTAGGCCTTGCTCCACCGCGCACTTTT
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	CTGTGATCGCGGAGAAGCAGGAACAGGTGATCGC
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC	TGAGCGTTGACGTTTCGGTCGGCATGGCAACGGA
GTTTCTATCCACGCCTCCGCGCGGGAGGCGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_023786783.1|1450128_1451163_-|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl|CDD|188360
NC_022997.1|WP_144083550.1|1444456_1445122_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786772.1|1441178_1441787_-|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_022997.1|WP_023786780.1|1446062_1446260_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NC_022997.1|WP_023786787.1|1454805_1455501_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187534
NC_022997.1|WP_023786785.1|1451835_1452783_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NC_022997.1|WP_023786781.1|1447038_1447239_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786784.1|1451159_1451819_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
NC_022997.1|WP_023786782.1|1449809_1450100_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_022997.1|WP_023786786.1|1452779_1454528_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NC_022997.1|WP_144083548.1|1441796_1442453_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786774.1|1442449_1442917_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786792.1|1459498_1459846_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786771.1|1440731_1441049_-|phage-tail-assembly-protein	unknown	unknown	gnl|CDD|378397
NC_022997.1|WP_023786779.1|1445111_1445993_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379352
NC_022997.1|WP_144083549.1|1443740_1444442_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_041316383.1|1455573_1457910_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NC_022997.1|WP_023786775.1|1443414_1443627_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NC_022997.1|WP_023786791.1|1459211_1459478_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786790.1|1458831_1459026_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_022997.1|WP_023786782.1|1449809_1450100_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.5e-29	96.8	0.0
NC_022997.1|WP_023786783.1|1450128_1451163_-|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	1.8e-149	492.2	0.0
NC_022997.1|WP_023786787.1|1454805_1455501_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	7.1e-84	275.3	0.0
NC_022997.1|WP_023786785.1|1451835_1452783_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	5.3e-110	361.8	0.1
NC_022997.1|WP_023786784.1|1451159_1451819_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	6.3e-33	109.1	0.0
NC_022997.1|WP_023786786.1|1452779_1454528_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	2.3e-164	542.7	0.0
NC_022997.1|WP_041316383.1|1455573_1457910_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	1.9e-54	179.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_023786783.1|1450128_1451163_-|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl|CDD|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NC_022997.1|WP_023786772.1|1441178_1441787_-|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00442542
NC_022997.1|WP_023786780.1|1446062_1446260_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.57986e-06
NC_022997.1|WP_023786787.1|1454805_1455501_-|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.21989e-111
NC_022997.1|WP_023786785.1|1451835_1452783_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	8.03164e-143
NC_022997.1|WP_023786784.1|1451159_1451819_-|CRISPR-associated-protein-Cas4	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	3.45825e-38
NC_022997.1|WP_023786782.1|1449809_1450100_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.98258e-34
NC_022997.1|WP_023786771.1|1440731_1441049_-|phage-tail-assembly-protein	gnl|CDD|378397	pfam10109, Phage_TAC_7, Phage tail assembly chaperone proteins, E, or 41 or 14. This is family of various Myoviridae bacteriophage tail assembly chaperone, or TAC, proteins.	0.000119397
NC_022997.1|WP_023786779.1|1445111_1445993_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379352	pfam13730, HTH_36, Helix-turn-helix domain.	5.78204e-05
NC_022997.1|WP_023786786.1|1452779_1454528_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	0
NC_022997.1|WP_041316383.1|1455573_1457910_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.30727e-54
NC_022997.1|WP_023786775.1|1443414_1443627_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	2.77808e-06

Protein sequences

>NC_022997.1|WP_023786781.1|1447038_1447239_+|hypothetical-protein
MSLAAARVAAQKCRESLAADVDSIEARSAKRAAARIAEAQLITFKTCAEAYVAAHEADWSNDKHRA
>NC_022997.1|WP_023786780.1|1446062_1446260_-|helix-turn-helix-domain-containing-protein
MDRLLLSPNEFAHRNGVSRVQVYRMLNSGEICAFKVGKQTKIPVEVEREWRERLPRYVPRAGCQS
>NC_022997.1|WP_023786779.1|1445111_1445993_-|helix-turn-helix-domain-containing-protein
MSIKGSARAQPRNDAPLIVSQKNFGDDFTEEKAKRIAAIRDDLHVHSSCFRLAHIIASYISSSTGIAWPKQETLAERMGFKSKEGIKKLLDPLVARGHLLIVEKSKGRGRATVYAFPAVIEDKRANSSSPINEEKDEQELVLSAERANCSSEKGEQELAPTSFKELQKEERGEGSALGGLTAPNRQGEPFNRFWAVYPKRAGYDLARCHFDKAIENGADPEAIIEGAGRYAAAREGQDEQFTKFASNWLRERCWLKEPTKRPQAQSRRSSTPHVHVNDVIRQLGYSLEAIDEN
>NC_022997.1|WP_144083550.1|1444456_1445122_-|hypothetical-protein
MKTEVAQRARNVPAQPNSPAAFLTAHVDARAVRDRYEVVLRLAGAEVRKLCIEYDGTPASCDKLKDLALHVWNRTPRFIDTHDALEKLKTAAESQASKAAISSIVSVMLQSRASFDPSRKAGYVDALLAVLLMENDLRPFSRAALAAAVYRVITNEEFLPEIAKVLRFIRDEQRGFHAAVEAVEQINEARHYAGQILEDTGVPHEPDQDLFDLGILEFVPF
>NC_022997.1|WP_144083549.1|1443740_1444442_-|hypothetical-protein
MAVSYPEPLDADALRALRARAEADHAQHCAQCALHRDLNTALRLIGKVQINRGLGPRDWVAFVASGGLGRLLARAEGHGDPSRVDCLPSLLNIERDPLDARVIDQIACSLESHAHFTRGKQGRRRGAEFFLALHLSYEFTGRFGELPKVSTSEQFLDGHDDLVSLFDVTGPFVRFARASAGDLGERALRDAVRDGRYACSIILEFGIVPPPYRSLQWIDMDRKVIPLCEVEAG
>NC_022997.1|WP_023786775.1|1443414_1443627_-|helix-turn-helix-domain-containing-protein
MSKTTYLSPREAASHLGLSASTLAKHRITGTGPRFFKLGGLVKYRADDLNEWARERLFRSTTEYIEKARA
>NC_022997.1|WP_023786774.1|1442449_1442917_-|hypothetical-protein
MKIKSPTPGTISVDVASALLKVSRRRFFQLVSDGWIQRSERGEYAIKEVVQGAIAFRDDQIARAEKRNADNRIRDARAREIELRTAREEASLVPTDEVIAYTSAVVGALMERLRKLPASVTSDPHEQQRISKIVEHIGRKVDEAGSEYRNAWRRS
>NC_022997.1|WP_144083548.1|1441796_1442453_-|hypothetical-protein
MTETTYLAAQCRCGAGGYLAPADAEYALKVLQYKRPQIVAGAVPTAAPDRTLRVATHEASHAAMVHVLGHELLSITADGQAHCLHAAIGSHIDRAAIALAGGHGERLIIERCEFRPYDDAVLETFNIVRALRMGGCDQCNAALAMFGYCGFDPSDADLLATYRRVEAATIDFLREPVARAVIRKLADRLMEIGTVDGAAAHRLIETSGVEFGSRRITI
>NC_022997.1|WP_023786772.1|1441178_1441787_-|hypothetical-protein
MIEIFKKLAGASRPATAAELQDALASIDEAALATALEAATSSRDEALLSGDEKRLERAEATLAMAHRDLDRGRAATEALTTKIAEAEKRETELAIETERAAIEKLANSVAADLKRVYPRASREIIDLIERLMEAEERVKKFNEKAVQGGYGLYIEEVDPRAFPMPSGIIWHGVAACTSLQPCKGSPGWGAARVSLECAGVKF
>NC_022997.1|WP_023786771.1|1440731_1441049_-|phage-tail-assembly-protein
MTSTSETVSAGPSKRTHHLKHPFTTADGKQVTEILFRRARAKDILAFEEELKRGGSDTGVTLAFLASVNGMSLDDLGEIDAEDMIEVGAMVVDFLPEQFKGAREE
>NC_022997.1|WP_023786782.1|1449809_1450100_-|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVRTSEPGGERRLRRVAKACRDFGQRVQYSVFEVEVDQAQWIKLKANLEGLIDPAHDSLRYYFLGTNWQRRVEHVGAKPAADLNGPLIV
>NC_022997.1|WP_023786783.1|1450128_1451163_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYVTTEGASLRKDGENLVAEVESAERARVPFHMLTSLVVFGGIFISPPLIQALAQLGITIVLLDRAGRFQARVEGPVSGNVLLRRKQYKVAEQPDEIVRSFVTAKIANQRLVLQRALRDYGSDMPPDRRERVEQVVDRQAAILRKVAFKTRGLDTLRGAEGEAALGYFSVFGDLIRSPDAAVCFRGRSRRPPLDPVNAVLSFLYTLLTHECRSAAEGVGLDPAVGFLHRDRPGRPSLALDLMEELRPIFADRLALSLINRRQLRAGDFEFQDSGAVLLNDDGRRTVLTAWQERKKEERRHPFLEEVAPLGLVPHLQALLLARHLRGDLDAYPPWIWK
>NC_022997.1|WP_023786784.1|1451159_1451819_-|CRISPR-associated-protein-Cas4
MPELDDPIPISALQHAVFCIRQAALIHIERLWEENRFTAEGRVLHEAAHDPSRRTRGLVRRVTALPLACRRLNLSGTADLVEFRREAPGGPETPFPVEYKRGKPKLHRADEVQLCAQAFCLEEMTNRSVTEGALFYGGTKRRVVVPFDVELRRLTEETARAFGSLLAAGETPPAVYKHDRCRACSLIDVCRPKATTKTAAGFLHRAVEETLLRDASEAP
>NC_022997.1|WP_023786785.1|1451835_1452783_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTALANRYDIVFLFDVKNGNPNGDPDAGNLPRIDPETSHGLVSDVSLKRKIRNYTELARGAEAGYRIYVQEGSILNERHREAYKAERPGDDTVEKAPKLNPRNDDEAKALTRFMCENFFDVRTFGAVMSTGINAGQVRGPVQVAFASSVEKILPLEISITRMAATNEKEKAAREKDAGDDRTENRTMGRKHIVPYGLYRAHIFVNAKLAERTGFSDADLKHLFASLKAMFEHDRSAARGEMATRRVVAFKHASALGNAPAHQLFERVKVQRKVGDDLYDVDSAKLDNYPPARAYSDYQVSVDLNGLPDGVEVVEL
>NC_022997.1|WP_023786786.1|1452779_1454528_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MTALASLARAYERMAARGETPAPGYSPQRIGFLVSLTSDGQPSGPPHDLREADGRRRTAALMAVPQPGKRTSGVMPNFLWDKTAYALGVTAGEAKRTAQEHRAFADKHREWLEGTTDEGLLALLGFLDFWTPEKFGELGWPEDMKDQNVAFALERERLDNIRIHDRPAAKALWARLSGDGEKTDALCLATGERGPLARLHPAIKGVWGAQTAGASIVSFNLNAFTSYGKEQGENAPLSEAAAIAYTEALNAFLRGTQNRIQIGDATTVFWADASDTNAARKAEGLFGAFSKVTDQGEAKKVAAILERIQRGLPVDDFDPVREGVRFHVLGLAPNAARLSVRFYVEDDFGEIARRYADHHERMRIEPEPKDGWPPMWRLLIETAALRKTENIQPNLAGDWMRAILTGSPYPLTLLSSIVMRLRADHDVNALRVAILKSVLIRNFKVKETPVSLDPEFKDAGYLLGRLFAVYEQVQVAALGTGVNATVKDKFFGAASAQPRKVFHILASGASNHLSKVAKQSKGRQVNLEKAISAIMELMKPGDDPFPASLPDKSQALFALGYYHQRNEFFRKAEKTTSGEDAQ
>NC_022997.1|WP_023786787.1|1454805_1455501_-|type-I-C-CRISPR-associated-protein-Cas5
MSYGVRLLVQGKYACFTRPEMKVERVSYDVMTPSAARGILEAIHWKPAIRWIVDEIHVLKPIRFQSVRRNEVGAKAPAASIRKAMRTGDVGDLALVVEDNRQQRASTLLTNVAYVISAHFIMTSRAGAEDNEGKHLDTFNRRARKGQCFHQPCLGTREFPAEFELLETGAPAPVADPDDRTASLGFGTPRDLGFMLYDIDHAGDRSSMVFRATLKDGVVKVPAPDSPEVRR
>NC_022997.1|WP_041316383.1|1455573_1457910_-|CRISPR-associated-helicase/endonuclease-Cas3
MHYAHSTENEDKSDWQTLVAHLREVAALAMQFGDAFGAGRAAALAGWLHDLGKYAEKFKLYIEGKGENCDHSTAGAKAVLELVRSDSDDTIMAELVAYAIAGHHAGLPDRIGGSGGSLNDRLKKKIPILDAAWKTEVEAETDNLVPRNFSLRQGDDQSFFQIAFLGRMIFSCLVDADRLNTEAHHAHVTGIEVDRTWPELPNEVAGLVAGFDAHLDDKLAKLTPAERAAPLNVLRRDVLAHVRGQTAMPKGVFTLDVPTGGGKTLASLAFALEHARAWSMRRIVYAAPFTSIIDQTAQIFRDILGDDAVLEHHAQVDTEKDLPEETGDRNAQSRERKLRRAMENWAAPVVVTTNVQLFESLFSHRPSRCRKLHNLANAVIVLDEAQTIPLPVLRPCVVALDELAHNYGCTIVLCTATQPALKAPDFRFGFETSHELALEPAKLHTAFERVTFEMAGVLSDNSLIEQLRQVPQGLVIVNSRKHARDLFLAAKDARIEGLIHLTTRQIANDRAEILTEIREELKHKKPCIVIATSLIEAGVDVSFPRVWRAEAGLDQIIQAAGRCNREWEQPKEHALVVVFQPSEAKPPPEIAGFADAMARVARTFPDPLVKPGIELYFREVYWQRGDNRHRDGLDDVPMPNLDGRKAPAKVLDQFAGNDGSTDFSYRKVGENFRLIRDGMAPIIIATDDQSKTILRRLRDGTITAGRAARELQRYLVQVPPRHRQRFVDNGHAEYVPGFETQFVVLKESLINTMSGFYSREQGLLWEKGDELGIEGNMI
>NC_022997.1|WP_023786790.1|1458831_1459026_-|hypothetical-protein
MAKKTRQIAPPVQGRATSEPLHIPAADLSDEELTSVQGGAAPIPFEKQLATDAGFIASKTEVIH
>NC_022997.1|WP_023786791.1|1459211_1459478_+|hypothetical-protein
MPLVFNDDILMGFVGDTFVFSMRDEQTGDTVSCEITRDGLQRAIQKKEVYDPRIAFSMYKARFGELASKRFDEGQRPARITIEDVEAF
>NC_022997.1|WP_023786792.1|1459498_1459846_+|hypothetical-protein
MRSLLGALVALSVILSATAAPATDAVSGKYWLKICENSITREGCIGYLSGLIHMELYASQRMPDGPLWCAPDDASVNDMMRTFVRFLEDRPELLHGSAVQLAHLAWARAYPCKRD

Crispr_ID: NC_022997_6

• CRISPR_ID: NC_022997_6
• CRISPR_location: 1473161-1473253
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_022997_6

Consensus_repeat	Method
TTCAGGCTGATAGGGCCTGAAACGATCATGGTCT	CRISPRCasFinder

spacers of NC_022997_6

>6.1|1473195|25|NC_022997|CRISPRCasFinder
CTTGAGTTAGACCGATGATTCACGT

CRISPR arrays and Neighbor proteins around NC_022997_6

CRISPR arrays

The CRISPR arrays of NC_022997_6

>merge|NC_022997|6|1473161-1473253|CRISPRCasFinder
TTCAGGCTGATAGGGCCTGAAACGATCATGGTCTCTTGAGTTAGACCGATGATTCACGTTTCAGGCTGATAGGGCCTGAAACGATCATGGTCT

>NC_022997|6|5|1473161-1473253|CRISPRCasFinder
TTCAGGCTGATAGGGCCTGAAACGATCATGGTCT	CTTGAGTTAGACCGATGATTCACGT
TTCAGGCTGATAGGGCCTGAAACGATCATGGTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_041316385.1|1464589_1465873_-|dihydrolipoyllysine-residue-acetyltransferase	unknown	unknown	gnl|CDD|237000
NC_022997.1|WP_023786799.1|1474128_1475550_-|iron-sulfur-cluster-binding-protein	unknown	unknown	gnl|CDD|224062
NC_022997.1|WP_023786807.1|1486324_1487089_+|FCD-domain-containing-protein	unknown	unknown	gnl|CDD|181879
NC_022997.1|WP_023786796.1|1470498_1471116_-|ubiquinol-cytochrome-c-reductase-iron-sulfur-subunit	unknown	unknown	gnl|CDD|239550
NC_022997.1|WP_023786794.1|1465926_1468596_-|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	unknown	unknown	gnl|CDD|236500
NC_022997.1|WP_144083659.1|1473481_1473919_-|LUD-domain-containing-protein	unknown	unknown	gnl|CDD|224473
NC_022997.1|WP_041317794.1|1483979_1484432_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|224991
NC_022997.1|WP_023786800.1|1475816_1476614_-|(Fe-S)-binding-protein	unknown	unknown	gnl|CDD|223325
NC_022997.1|WP_023786801.1|1476871_1477636_+|FCD-domain-containing-protein	unknown	unknown	gnl|CDD|181879
NC_022997.1|WP_158412842.1|1459898_1462517_-|autotransporter-domain-containing-protein	unknown	unknown	gnl|CDD|226973
NC_022997.1|WP_023786803.1|1479723_1481187_-|aldehyde-dehydrogenase	unknown	unknown	gnl|CDD|143407
NC_022997.1|WP_023786804.1|1481606_1483976_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl|CDD|224446
NC_022997.1|WP_023786797.1|1471739_1473095_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786792.1|1459498_1459846_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_081717665.1|1463152_1464583_-|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl|CDD|180579
NC_022997.1|WP_023786791.1|1459211_1459478_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023786795.1|1468699_1470439_-|PQQ-dependent-dehydrogenase,-methanol/ethanol-family	unknown	unknown	gnl|CDD|199835
NC_022997.1|WP_023786806.1|1484525_1486175_-|L-lactate-permease	unknown	unknown	gnl|CDD|224535
NC_022997.1|WP_023786802.1|1477688_1479650_+|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225822
NC_022997.1|WP_023786790.1|1458831_1459026_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_041316385.1|1464589_1465873_-|dihydrolipoyllysine-residue-acetyltransferase	gnl|CDD|237000	PRK11855, PRK11855, dihydrolipoamide acetyltransferase; Reviewed.	0
NC_022997.1|WP_023786799.1|1474128_1475550_-|iron-sulfur-cluster-binding-protein	gnl|CDD|224062	COG1139, COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion].	0
NC_022997.1|WP_023786796.1|1470498_1471116_-|ubiquinol-cytochrome-c-reductase-iron-sulfur-subunit	gnl|CDD|239550	cd03467, Rieske, Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.	2.03945e-15
NC_022997.1|WP_081717665.1|1463152_1464583_-|dihydrolipoyl-dehydrogenase	gnl|CDD|180579	PRK06467, PRK06467, dihydrolipoamide dehydrogenase; Reviewed.	0
NC_022997.1|WP_023786794.1|1465926_1468596_-|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	gnl|CDD|236500	PRK09405, aceE, pyruvate dehydrogenase subunit E1; Reviewed.	0
NC_022997.1|WP_144083659.1|1473481_1473919_-|LUD-domain-containing-protein	gnl|CDD|224473	COG1556, COG1556, Uncharacterized conserved protein [Function unknown].	8.74551e-24
NC_022997.1|WP_041317794.1|1483979_1484432_-|(2Fe-2S)-binding-protein	gnl|CDD|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	6.81203e-75
NC_022997.1|WP_023786800.1|1475816_1476614_-|(Fe-S)-binding-protein	gnl|CDD|223325	COG0247, GlpC, Fe-S oxidoreductase [Energy production and conversion].	2.775e-55
NC_022997.1|WP_023786801.1|1476871_1477636_+|FCD-domain-containing-protein	gnl|CDD|181879	PRK09464, pdhR, pyruvate dehydrogenase complex transcriptional repressor PdhR.	2.86931e-52
NC_022997.1|WP_023786802.1|1477688_1479650_+|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl|CDD|225822	COG3284, AcoR, Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription].	1.04318e-155
NC_022997.1|WP_023786803.1|1479723_1481187_-|aldehyde-dehydrogenase	gnl|CDD|143407	cd07088, ALDH_LactADH-AldA, Escherichia coli lactaldehyde dehydrogenase AldA-like. Lactaldehyde dehydrogenase from Escherichia coli (AldA, LactADH, EC=1.2.1.22), an NAD(+)-dependent enzyme involved in the metabolism of L-fucose and L-rhamnose, and other similar sequences are present in this CD.	0
NC_022997.1|WP_023786804.1|1481606_1483976_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl|CDD|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	1.40823e-73
NC_022997.1|WP_158412842.1|1459898_1462517_-|autotransporter-domain-containing-protein	gnl|CDD|226973	COG4625, COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain [Function unknown].	4.09568e-49
NC_022997.1|WP_023786807.1|1486324_1487089_+|FCD-domain-containing-protein	gnl|CDD|181879	PRK09464, pdhR, pyruvate dehydrogenase complex transcriptional repressor PdhR.	8.36542e-55
NC_022997.1|WP_023786795.1|1468699_1470439_-|PQQ-dependent-dehydrogenase,-methanol/ethanol-family	gnl|CDD|199835	cd10277, PQQ_ADH_I, Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase). This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.	0
NC_022997.1|WP_023786806.1|1484525_1486175_-|L-lactate-permease	gnl|CDD|224535	COG1620, LldP, L-lactate permease [Energy production and conversion].	4.59125e-171

Protein sequences

>NC_022997.1|WP_023786797.1|1471739_1473095_+|hypothetical-protein
MLGGKTFLFSAAALVGVSAGLLGSDRSFAADFGGNCCADLEERIAELEATTARKGNRKVSLTISGWVTQQIMGWDDSISSDAYVGTSLNDLGTRLHFDGSASINNEWSAGYSLRFDITGANGFVQDASNARGGEGPPGLLNSYWWIKSERLGRVSVGRQSHSADDTWVDVSGAGSIFAANLVIFDGQNFQLVPQGTGRRAKARWGDIGNCYTTGVGIFADCAGDRTDSVRYDTPTIAGFVASTSWGGDDHWDVALRHAGEFGAFKTAFGMSYHENKGDPRINTITDTSIFQVSFSALHQPTGLFGVVYYGNEDPDGFKDSDQLYLKAGLRTNLTSLGATIFYGEYGRGDDMFSGLEGGAVFSGVTDLCDGFAGTGGNIDTACAGGAAHTSGSTFERFGFGVVQELDAASMALWLKYKNYDGEIDFIDAGGATGKESLENLHIYALGAAIFF
>NC_022997.1|WP_023786796.1|1470498_1471116_-|ubiquinol-cytochrome-c-reductase-iron-sulfur-subunit
MQKDTRTRRDAGGADEDQCEVGRRNVLQGLAFSCCAVAAGIAASAPADAQTTRGRRAEPGHRFAFMTGDKEGEVVAPSDVKIGEQPLLVYPMDAETGDILASRANLLILMRVPEGDLDPSMEQHAAAGIVAYSAICTHEGCPISGQHENPRMAVCNCHGSTFDVGNNGVVVQGPAVRRLAMLPVTITDGALVVAGKLNGPIGPPA
>NC_022997.1|WP_023786795.1|1468699_1470439_-|PQQ-dependent-dehydrogenase,-methanol/ethanol-family
MKLRSSVAVLALVAAPATMQAAEFKLSDYKPVTEDRMKNPEAENWLLTKGNYAGWSYTPLDQITTENVSRLRPVWSAATGVNSGHEAPAVVNGDYMFVATPHNQVLAFDAKTGRSLWRFVREVPEGMGALHRTNRGVALWGDKVYVGSIDCMLTALDAKTGTKVWEAEVCDWETKSAYITSAPLAVKGKIIIGPSGGEFGVRGYIKAFDAETGKEAWTTYSVPAPGEPGSETWPQDGKWKDAWKNGGGTMWMPGNYDAKNDVIYWGVGNGAPWIADQRPGDNLYIASSLAINPDDGKIVSHFQYHHNDGWDWAAMNAPTLVEFNKDGNTVEGLISAQRNGVLYWLERDATGNISFDQAEKYVYNNVFTSIDPKTGRPTYNQDAIPGTGKSATYCPTLWGGKDWPYEAYSPKSGMLYIPYNENHCSTLTGIIQPIIPGVWSAGVDINALNIELRDGWDHIGGIQAWSVDGRKEEWRVKYPGSWNWGSILTTGGGVLFAGGTNDRMFRAYDEKSGKLLWEFPTPSGIISPPSAFSVDGKQYIAVVSGWGVDAAWVQGKMNELAGWEKQVPEGGSVWVFALD
>NC_022997.1|WP_023786794.1|1465926_1468596_-|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type
MNDQIDDRNAERREWEDAISSVLAFEGRHQADKVLSGAVEIARRSGARLPFAAHTAYVNTIPADEEPPHTGVREVEHRIRSAIRWNAAMIVLRANKTSSDLGGHIASFQSAATLYDTGFEHFWHAPSENHGGDLLFIQGHSSPGIYARAFLEGRLTEEQLSAFRQEVDGLGLSSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFLKYLHGRNFADTSNRHVWAFCGDGEMDEPESLGAIALAGREKLDNLIFVVNCNLQRLDGPVRGNGKIVQELEGVFRGAGWNVIKVIWGSNWDPLLAADTSGRLRQLMEECVDGEYQDFKSKDGAYIRENFFGRYPETAAMVANWSDDEIWKLTRGGHDPSKVYAAYKRAVTHTGQPTVILAKTVKGYGMGKAAEAQMIIHQQKKMDIDALRQFRDRFQVPVPDERIGELPFVRFAEDSEEAGYLRARRAELGGFLPARRRRSESLAAPELSQFDALLKATPGREISTTMAFVRLLSTLLRDKTLGPRVVPIVPDESRTFGMEGMFRQFGIFSQVGQLYRPSDAGELMYYREDQKGQMLQEGISEAGAMSSWIAAATSYSTSNVPMIPFYIFYSMFGFQRIGDLAWAAGDSRARGFLIGGTSGRTTLNGEGLQHQDGHSHLIAATIPNCVSYDPTFAYEVAVIVRNGLARMIERQEDVFHYITVLNENYEHPAMPEGVEDGIVKGMYLLKSTSGTAKGRRHRVQLMGSGAILREVIAGAELLESDFGISADIWSVTSFTELAREAQEVERWNLLNPEEPPRTPYVTQLLRERGPGPVIASTDYTKAFAEQIRPFVPNAYRVLGTDGFGRSDTRRKLRFHFEVDRHFVVASTLKALADENRIPSSRVSDALARYGIRPDKPNPVKI
>NC_022997.1|WP_041316385.1|1464589_1465873_-|dihydrolipoyllysine-residue-acetyltransferase
MSLIEVKVPNIGDYSGVPVIEVLVTAGDVVSVDDPLVTLESDKASMEIPAPSAGKVAEVLVNVGDTVSEGHLILRLEAEANEAGTAAAADAPTPPAAARPEADPDGPADPSPPPASSNVSSNTSVLPAPADFDGLNASPSVRRLARELDIDLAALKGTGEKGRITKADVKAALGGGSATGRALTIADVPQPDFSKFGPVTVAPLSRLKRLSGPHLHRAWVSIPHVTHTDEADITELETYRRTLDAEARAKGYRVTMLSFLMMASVATLKQFPEFNASLSPDGQSLILKRYYNIGVAVDTPDGLVVPVIKDADRKRILELSQELSTVSQRMRDGKIAPADIQGGTFSISSLGGIGGTGFTPIVNAPEVAILGVVRAVTRPVWNGETFTPRLMLPLCVSYDHRVIDGALAARFTRRLAEILGDVRQLVL
>NC_022997.1|WP_081717665.1|1463152_1464583_-|dihydrolipoyl-dehydrogenase
MTKAPDIETDLLVLGAGPGGYTAAFRAADLGKTVVLVERAPVLGGVCLNVGCIPSKALLHTAKVIEETREMAGAGLRFGAPDIDLGQLRAWKTGIVGKLTSGLSGLARQRKVTVVTGTGRFVSPHALEVVHEGAVQRIGFAQAIVAAGSEPARLPFVPHDDPRVLDSTGALDLEDVPKRLLVIGGGIIGLEMATVYHALGSTVSVVEVTDQLIPGVDRDIVAPLMKRVEARYEAIHLGTRVTKVEPGDTGLTVAFEGPAAPQSKTFDKVLVAVGRVPNGKLLNLEAAGVGVDDRGFVPVDRRMRTNVPHIFAIGDIVGQPMLAHKAVHEGKVAAEVAAGLASAFDARVIPSVAYTDPEVAWVGLTETEAKANGVSYGKGAFPWAASGRALSLGRDEGLTKVLFDPETHRILGCGIVGPNAGDLIAEAALAIEMGADAADIAATIHPHPTLSETIAQAAEMFEGTITDLMPKPARRT
>NC_022997.1|WP_158412842.1|1459898_1462517_-|autotransporter-domain-containing-protein
MQNSNTVSGGGGGGGGSGTTGGNGGHGSATLGVGGAGGTTAGADGGAGSSGGTYGAGGGGGGAHGYLSPSLLPTVDVKGGDGGGGGHSTGGGGGGGGGGNGVVVNGSNFTGIISTIVAGGNGGHGGNGGSTAEGGSGGRGGEGLYVLHSGHDIEITGTITGGNGGNLGSAGAGVNTGYAGNGANAVWLYNSRLAVTGTVSGGNAGAGGPANGGHGVYGENVDLVVTGTIRGGINSDSSQALAVRFTGGTNSVTIEPTASFVGGVQGAGNDAIVLSGATDGSIAYTTQFNGFSELVKNGTSAWTLTGSNFTGNTTINSGRLEVDGQVGGAGATTNVVGGTLGGTGTIVGTLNVGPGAIHAPGNSIGTQTVNGPYILQAGSILEIEVNAAGQSDLVIVNGTVDITGAALRVLAENGNYAAATDYLIIDNDGVDAVVGTFAPITSNLAFLTPSVSYTGGDGNDVVLTMTRNSTALTSVADTPNQTAVAGAMNGLPPTNPLVNIVLGQSAEGARQSFDALSGEVHATLSATLARDSRFTRNALFARLQQAFHARGAAGSTTQTASLANTGTTSVAGSFDAPMMGLGMGSGSASGYDAPPPASPLVFWTQAFGSWGDTDGDGNAATAKRTIGGFLSGVDTGIGYGWRAGAALGYSRSNVSVSQRISSAEIDSYHLAAYTGGPVGAFALRGGASWSWSDIDTERTVVFPGFLDRVEADYDGDTGQIFGEIALPLTAGGLAYEPFAGLAYAHVSTDRFTEQGGAAALDGFGGSQDVGFSTLGIRFAATTRIGGTTVTPRASIAWQHAFGDTDPTRALAFASGAPGMTITGVPLARNAALIEAGLDISLSPSATLGISYNGEIASDVEDHGVTGRMNWRF
>NC_022997.1|WP_023786792.1|1459498_1459846_+|hypothetical-protein
MRSLLGALVALSVILSATAAPATDAVSGKYWLKICENSITREGCIGYLSGLIHMELYASQRMPDGPLWCAPDDASVNDMMRTFVRFLEDRPELLHGSAVQLAHLAWARAYPCKRD
>NC_022997.1|WP_023786791.1|1459211_1459478_+|hypothetical-protein
MPLVFNDDILMGFVGDTFVFSMRDEQTGDTVSCEITRDGLQRAIQKKEVYDPRIAFSMYKARFGELASKRFDEGQRPARITIEDVEAF
>NC_022997.1|WP_023786790.1|1458831_1459026_-|hypothetical-protein
MAKKTRQIAPPVQGRATSEPLHIPAADLSDEELTSVQGGAAPIPFEKQLATDAGFIASKTEVIH
>NC_022997.1|WP_144083659.1|1473481_1473919_-|LUD-domain-containing-protein
MLVPAILRLLPPPPQKPDISVAPALAHLGWPADWSINFGAGRRTEPLSVTLAVAGIAETGSVVLRSAPASPTTLNFLPDMHVVVLRADDVVAHTEDAWARLRAEGGDWPRTVNIIAGPSRTADVGGIIVRPAHGPKSVHLVLCDS
>NC_022997.1|WP_023786799.1|1474128_1475550_-|iron-sulfur-cluster-binding-protein
MLVNGKDFSSRASKAPADAGLQQQVSNLKTGFVAARARAVAALPEYEAMRDAGAAIKDHTLANLDFYLERFERAVVDRGGHVHWAADAEEACRIVREICTRTGARTVTKGKSMVSEEIGLNEALEADGLDVVETDAGEYIVQLAKEAPSHIVMPTVHKTTNEISDLFFEHHRRHGFSERVTDAAELIAQVRSVMREKYFSADIGITGANFLVAETGSNIIVTNEGNGDLTCTLARVHIVTAGIEKVVPTLNDASVLLRLLARSALGIETTSYTTLSTGPRRPGDADGPEEYHVVLVDNGRTKMLSGAFRPMLRCIRCGACMNHCPVYLAVGGHTYASVYPGPMGAVLTPMIARHEAANELPHACTLNGRCQQVCPVKIPLPDLLRRLRHEQWEDGFIKGRSRWGLGVWSWLATRPALYRVATRLGVQVLRWLGRSRGRIGHLPLAGEWTAGRDLPAPQGTTFHAAWAKRKRQP
>NC_022997.1|WP_023786800.1|1475816_1476614_-|(Fe-S)-binding-protein
MTKIDDAPSTTGGRPRVGLFVTCLVDLFRPGVGFAAVKLLEDAGCSVEVPEAQVCCGQPAYNSGDQGAARRIAKQVIEAFQGFDYVVGPSGSCMATVRKEYPAMFDGDVTWHARAVALAERSYELMSFLTDVMGMSAVTASFHGTATYHDSCSGLRTLGIKAQPRTLLATVEGLTLTELQDAETCCGFGGTFCVKYPEVSVRMVSDKVANIEMTAADTVLGGDLGCLMNIAGRLKRLGKPVRVYHAAEVLAGMAGPAGIGDPEKG
>NC_022997.1|WP_023786801.1|1476871_1477636_+|FCD-domain-containing-protein
MTERIKPQRVAEAIAEHIEQLILQGVLRPGERLTPERELAEKLDVSRASLREAIEMLAGRGLLITTRGGTHVAQFLSPLLKPLASLLENNAQVTADYFEFRQGVDAQSARYAALRASDIDREAIRACVARMKKAHEIADPTEEAQADVDLHISIYEAAHNAVVLHIMRGLVELLRTNIFYSRRQLYQRAAVRNKLLAQHLAIADAILAGNPKAAEAAATDHVRFTFNNVEEILRDGARLKASLLRVARSDYLAS
>NC_022997.1|WP_023786802.1|1477688_1479650_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MNVFGKGKVADRSPEYAHAKRIVDEIARDECDVAEDMSSLIVSSWKRCVSEYKLDRGGHKGPEIVTSNELKRAVDPLDLLRHVARPEIERLMEQVGGSGYVVMLADPNGIALDVLSAAAPDRALRRVGVCPGATWGEEQAGTNGIGTSIASRCAVTIHRSQHFFFNYSGLTCTAAPIFGSDGQVMASLDASSVADLPKEMQPLVRELVSATARRIERRYFLEKNRNRAIVRVEWGLDSHHDGSGLILALDDNGRTIEVQGGGGDHARATNCGALIGNPLSAFMEIAWQDVARSAKSPHVERIGIAHLKGSDRPCFASLIAPARSAGWAPSRRLASGAAGACKLDLDFLAGSDPVMREHVRTIRRLVDKSLPILLYGETGTGKEEFARGIHEVGARSAKPFVVIDCSSIPESLIESELFGYETGTFTGARREGRRGRIAEANGGTLFLDEIGDMPLPLQTRLLRVLAQGEVVPLGAAKPIKVDFNLICASHQDLPKMVSEGTFRQDLYYRIAGIRLELPALRARTDKESVILGALAVEAQKMALGVPPAISPEALKILLAQRWPGNMRELRLALRYALACSGEDEISQDRLPNWLNLGAGDNAPSPVGDVPDAPNLIDALERNRWCISDAACELRVSRQTLYRWIKKENLSRPT
>NC_022997.1|WP_023786803.1|1479723_1481187_-|aldehyde-dehydrogenase
MQLFTQQPGAAAAYQNFIDGKFVESRGNTIDVSNPATLDVIARVPDSGSEVVDQAVQAAKRAQPAWEKLPAIERARHLKAIAAKVRANAEPLARLITEEQGKVLPLARIEVNFTADYIDYMAEWARRIEGEILTSDRAGESIFLFRKPIGVTAGILPWNFPFFLIARKMAPALVTGNTIVIKSSEETPLNAFAFAGLVAETDLPAGVFNLVSGTGANTGAHLAAHRDVGLISFTGSVETGSKIMQMAATNLTRVNLELGGKAPAIVLADADLDLAAKAIYDSRVINTGQVCNCAERVYVARPVADAFLDRITRLMRETRYGDPLAMPDLNMGPLVNRAGLDKVTGMVDRARAAGAEVVTGGKPADVSRGHHYEPTVIANCRADMEIMQKEVFGPVLPIQIVDDVEEAVALSNASDYGLTSSIFTNDLNTAMRASRDLRFGETYINREHFEAMQGFHAGRRKSGIGGADGKHGLYEFTETQAVYLQHG
>NC_022997.1|WP_023786804.1|1481606_1483976_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MLHYLKKEAEKAERKTSPALIENVSRRSFVGGALAASGLVLAVRIPSASAREKLTPYPTGGADMPHGYGSASDPHVFVSIKPDGSVTILAHRAEMGTGVRTSLPMVVADEMEADWSQVSIEQAVGDEPLYGNQDTDGSRSMRHYIQPMRECGAAMRQMLEQAAATKWGIDASRVRAKAHKVAQLDDAGKETGETLGFGDLAEAAMALPVPARETLLFKTPDEFSYMRKGETKITDLHDITTGKAIYGADVRLPGMKYAVMIRPAVLGEKLKSFDGAAALKVPGVEAVHEIEGFHEAPRKFAPLGGVAVVANSTFAALQGRDALTVEWEPSADHAGYNTDAFFEEMSETSKKPGKVIRDLGNVDTTFANAKTVFSEEYRCQHLNQASMEPLVAVARVADGKCEVWAPVQSPYGAREDLAKALELPIEDVTVHVTLLGGGFGRKSKWDFMVEAALISRKIGGAPVLLQWTREDDMHHSFYHTVSVERIEMAFDDAGKVTGFRHRTVAPSILSTFAPDSGYQFNIEYGMGFVNTPYEIANVRCENGQAFAHTRIGWLRSVSNVPRAFAVQSAVAEAAHAMGRDHREFLLELIGSDRILDLKALGYPEDFWHYGDPYEPFPVDTARLKHVINLATEKAGWGKELPKGQGLGLAAHLSWHNYVATVVHVDVKDDGTITVPHAVTAMDCGFYVNPERIRSQVEGAAVMGMSHGLYSGITFKNGAVEQSNFYDFEIARMSNFPKVVDVLLVEPQPGRNAAGVGEPGLPPFAPALANGVFAATGKRLRNMPMGEKVA
>NC_022997.1|WP_041317794.1|1483979_1484432_-|(2Fe-2S)-binding-protein
MATFTVNGESRSFDGDPGTPLLWYLRDDAGLTGTKYGCGQGLCGACTIHLDGVAVRSCMTTIEMADGKAVTTIEGLHPEGDHPVQKAWRELSVPQCGFCQAGQIMQAASLLAENQAPSDDEITQEMSGNLCRCGCYQRIHAAVRLAAGGV
>NC_022997.1|WP_023786806.1|1484525_1486175_-|L-lactate-permease
MWSQVYDPLGSMVLSSTVAAVPIVVLLGAIGVFNIRAHIAAMLGLVAALIVAVFAYGMPVQMAGLAAAYGAAFGLLPIGWIILNVIFLYQLTNEKGEFAVLQRSISTVSDDRRLQLLFIAFCLGAFFEGAAGFGTPVAVTAAMLIGLGFTPLAASGLSLIANTAPVAFGALGTPVIALSAVTGLDLHELSGMIGRQLPFFSVMVPFWLVWAYVGFRKMMEVWPPILVAGVSFAVPQYLVSNFHGPWLVDIVAAIVSMAALAGFLRIWKPSDRAAATAAELAGAGNAGSVPVKEDLPAPAVRRAWTPWVVLSICVFLWGAPQVRAALDGIWVAKVPVMGLHEQVQKVPPVVAEAHTEAAVYTFNILSTTGSGILLAAIFSGFFLGYSLSGMVRMYLRTIYLVRYSLITISCMLAIGFVTRYAGTDATLGLALANTGWLYPLFGTLIGWLGVALTGSDTASNVLFGGLQKVTAEQLDLSPVLMASANSSGGVMGKMIDAQSIVVASTATRWYGHEGSILRFVFFHSVALAILVGLFVMGQAYVWPMTLLVP
>NC_022997.1|WP_023786807.1|1486324_1487089_+|FCD-domain-containing-protein
MEAVQTQRLSDAIATRIEKLILEGTLRPGEKLASERDLAQRLDVSRPSLREAIDKLVKRGLLTASRSGTSVAEFLTPMMTPLANLYRDHENAAADYLEFRQCVEAQAARFAAERATPLDRAAIRDCLAELKKAHKAADPAREAEADASLHLRLYEASHNFLVLHVMRGLGELLRDHIFFNREHLYRRAGVREKLLAQHLAIGKAVIEGRPDEAEKAAATHIAFVFGTVEKIEEDKERLKCSMSRVGRNAFLAPR

Crispr_ID: NC_022997_7

• CRISPR_ID: NC_022997_7
• CRISPR_location: 2508782-2508926
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_022997_7

Consensus_repeat	Method
GCCTACGCAGAATTGGTCGCGCCC	CRISPRCasFinder

spacers of NC_022997_7

>7.1|2508806|42|NC_022997|CRISPRCasFinder
TGTGGACAAGTCATCCGCCGATCTTCAATCACTTAGCATGGT
>7.2|2508872|31|NC_022997|CRISPRCasFinder
CTACGCAGAATTGGTCGCGCTTCGAGGCCCG

CRISPR arrays and Neighbor proteins around NC_022997_7

CRISPR arrays

The CRISPR arrays of NC_022997_7

>merge|NC_022997|7|2508782-2508926|CRISPRCasFinder
GCCTACGCAGAATTGGTCGCGCCCTGTGGACAAGTCATCCGCCGATCTTCAATCACTTAGCATGGTGCCTACGCAGAATCGGTCGCGCCCCTACGCAGAATTGGTCGCGCTTCGAGGCCCGCCCTACGCAGAATTGGTCGCGGGG

>NC_022997|7|6|2508782-2508926|CRISPRCasFinder
GCCTACGCAGAATTGGTCGCGCCC	TGTGGACAAGTCATCCGCCGATCTTCAATCACTTAGCATGGT
GCCTACGCAGAATCGGTCGCGCCC	CTACGCAGAATTGGTCGCGCTTCGAGGCCCG
CCCTACGCAGAATTGGTCGCGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_023787750.1|2513138_2513555_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_144083586.1|2515912_2516179_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023787744.1|2505548_2506625_+|site-specific-integrase	unknown	unknown	gnl|CDD|271177
NC_022997.1|WP_023787742.1|2503501_2504329_-|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NC_022997.1|WP_023787740.1|2501251_2502751_+|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl|CDD|100091
NC_022997.1|WP_023787752.1|2514435_2514789_+|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl|CDD|368576
NC_022997.1|WP_023787757.1|2517972_2519490_-|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NC_022997.1|WP_023787749.1|2510510_2512472_-|cation-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319849
NC_022997.1|WP_023787745.1|2506814_2507441_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|222854
NC_022997.1|WP_023787738.1|2499678_2500392_+|TIGR02281-family-clan-AA-aspartic-protease	unknown	unknown	gnl|CDD|226106
NC_022997.1|WP_023787746.1|2507478_2507754_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_081717713.1|2504344_2505394_-|tRNA-dihydrouridine(20/20a)-synthase-DusA	unknown	unknown	gnl|CDD|236991
NC_022997.1|WP_023787747.1|2507750_2508776_+|hypothetical-protein	unknown	unknown	gnl|CDD|309782
NC_022997.1|WP_023787751.1|2513559_2513988_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023787741.1|2502877_2503489_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023787753.1|2514792_2515875_+|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl|CDD|367497
NC_022997.1|WP_023787739.1|2500474_2501047_+|TIGR02281-family-clan-AA-aspartic-protease	unknown	unknown	gnl|CDD|131334
NC_022997.1|WP_023787755.1|2516175_2516487_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023787756.1|2516604_2517219_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_041316502.1|2509266_2510100_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_023787745.1|2506814_2507441_+|AAA-family-ATPase	gnl|CDD|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	6.1147e-33
NC_022997.1|WP_023787744.1|2505548_2506625_+|site-specific-integrase	gnl|CDD|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.07153e-27
NC_022997.1|WP_023787742.1|2503501_2504329_-|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.53708e-20
NC_022997.1|WP_023787740.1|2501251_2502751_+|phosphomannomutase/phosphoglucomutase	gnl|CDD|100091	cd03089, PMM_PGM, The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a bisphosphorylated sugar intermediate. The reaction involves two phosphoryl transfers, with an intervening 180 degree reorientation of the reaction intermediate during catalysis. Reorientation of the intermediate occurs without dissociation from the active site of the enzyme and is thus, a simple example of processivity, as defined by multiple rounds of catalysis without release of substrate. Glucose-6-phosphate and glucose-1-phosphate are known to be utilized for energy metabolism and cell surface construction, respectively. PMM/PGM belongs to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the phosphoglucomutases (PGM1 and PGM2). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	3.85223e-151
NC_022997.1|WP_023787752.1|2514435_2514789_+|plasmid-mobilization-relaxosome-protein-MobC	gnl|CDD|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	8.74307e-05
NC_022997.1|WP_023787747.1|2507750_2508776_+|hypothetical-protein	gnl|CDD|309782	pfam04796, RepA_C, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood.	2.28086e-26
NC_022997.1|WP_023787738.1|2499678_2500392_+|TIGR02281-family-clan-AA-aspartic-protease	gnl|CDD|226106	COG3577, COG3577, Predicted aspartyl protease [General function prediction only].	3.77864e-49
NC_022997.1|WP_023787749.1|2510510_2512472_-|cation-translocating-P-type-ATPase	gnl|CDD|319849	cd07551, P-type_ATPase_HM_ZosA_PfeT-like, P-type heavy metal-transporting ATPase, similar to Bacillus subtilis ZosA/PfeT which transports copper, and perhaps zinc under oxidative stress, and perhaps ferrous iron. Bacillus subtilis ZosA/PfeT (previously known as YkvW) transports copper, it may also transport zinc under oxidative stress and may also be involved in ferrous iron efflux. ZosA/PfeT is expressed under the regulation of the peroxide-sensing repressor PerR. It is involved in competence development. Disruption of the zosA/pfeT gene results in low transformability. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_022997.1|WP_081717713.1|2504344_2505394_-|tRNA-dihydrouridine(20/20a)-synthase-DusA	gnl|CDD|236991	PRK11815, PRK11815, tRNA dihydrouridine(20/20a) synthase DusA.	0
NC_022997.1|WP_023787753.1|2514792_2515875_+|relaxase/mobilization-nuclease-domain-containing-protein	gnl|CDD|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	1.42025e-21
NC_022997.1|WP_023787757.1|2517972_2519490_-|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	2.35686e-138
NC_022997.1|WP_023787739.1|2500474_2501047_+|TIGR02281-family-clan-AA-aspartic-protease	gnl|CDD|131334	TIGR02281, Uncharacterized_protein_RP867, clan AA aspartic protease, TIGR02281 family. This family consists of predicted aspartic proteases, typically from 180 to 230 amino acids in length, in MEROPS clan AA. This model describes the well-conserved 121-residue C-terminal region. The poorly conserved, variable length N-terminal region usually contains a predicted transmembrane helix. Sequences in the seed alignment and those scoring above the trusted cutoff are Proteobacterial; homologs scroing between trusted and noise are found in Pyrobaculum aerophilum str. IM2 (archaeal), Pirellula sp. (Planctomycetes), and Nostoc sp. PCC 7120 (Cyanobacteria). [Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.31664e-41

Protein sequences

>NC_022997.1|WP_023787747.1|2507750_2508776_+|hypothetical-protein
MTFDVEIRDADLVAELDMARETPGFEFKRMELSQKQASRDKLASLSRDARRRELVRRKLEDTPTDADDLRHIHSVLAMCGLPYSRQPLSVREYERKQGRMSLVVEAGKLRNPETGNRIEQPLPFGPKARLLLMHLCSEAIRQQGPTIEVADSLTGFIRDMGFPVTGGKKGTLQAFKEQINALAACKLSVGMWDGRHAVEYQGMPFSRIDVWLPTSPDQMMLWPSTLTFSMDFYTTLAKHALPIRAEAVRAFAGSARKLDMYFWFNYRLHRLRQPLPISWNALAEQFGGDYGRQRDFKRGFADDLKDVLDVFPKLPVKLTEAGMTVSPAGPDALYLPPLRKR
>NC_022997.1|WP_023787746.1|2507478_2507754_+|hypothetical-protein
MSHNKLREAMMGVQGRTEATQPAAPQPAAAATRAKPQVATRVGRRAVTVWISAEAFRQLHLIGLDKECSVQDMGVEAFNDFFRKHDKSAVA
>NC_022997.1|WP_023787745.1|2506814_2507441_+|AAA-family-ATPase
MKTIALLSQKGGSGKTTLSLNLAIAAARANLSTVVIDLDPQQSASRWARLRKDGNPVIVSGHAPNLATLLAQARDGDAALAFIDTAPKSESASLIAAKAADLLIIPCQPSSLDLDAVADTVNIAKLAARPAVFVLNGCKAGSSLTEMAAEALADYGLPVLPVRIGSRVAFIKSLTEGKGVVEFEPSGRSAQEIRQLFTLTRKHADMRG
>NC_022997.1|WP_023787744.1|2505548_2506625_+|site-specific-integrase
MASIVKLPSGNWRAQLRHRQKSISKTFKLKSQALRWATEQQDCIERGQTPTARDSIKTDTVGEFIKLHLDDMAEVGKAAQRSKECALLRLQDDRDVGKVKVANFTRERVIEFGRRRAKEGAGPSTLSGDLSFIGTVFEHASSIYGHKVPMEDLRLGRGALVRLGLVGKSVERERRPTADELNRLLAFFRFRPRLVIPMERIVKFAVATAMRQDEITRILYEDFNRDERTVLIRQRKHPRDKASNNQVVPLISDAGFDPVTLIDEQMQWVSPKGAIFPYCARSIGAAFRRACIELQIDDLHFHDLRHEGISRLFEADWDIPAVASVSGHRDWKMLQRYTHLRPSYVASRARRGNRVSAS
>NC_022997.1|WP_081717713.1|2504344_2505394_-|tRNA-dihydrouridine(20/20a)-synthase-DusA
MLLNYIGKCVQSQSHRFCVAPMMDWTDRHCRHFHRLLSRNARLYTEMVTAEAVIHGDRARLLGFGPEEHPIALQLGGSDPEKLAHAASIGEAEGYDEINLNVGCPSPRVQEGCFGAALMAEPARVAACVAAMASRVSTPVTVKCRIGIDDQDSEADLTRFIEAVSDAGCRLFIVHARKAWLDGLSPKENREIPPLDYARVYRLKAARPDLTIVINGGIESLDEATSHLEHVDGVMVGRAAYQTPYLLADVDHVLFGADAPPPARGDVLTRLVPYVREHIARGGRLNSVTRHILGLYHGQPRARVFRRYLSENGVGEGPGIDVLLDAIAIAEGRPRDADEAVETAAFAAE
>NC_022997.1|WP_023787742.1|2503501_2504329_-|sulfite-exporter-TauE/SafE-family-protein
MELALANGDLLWLVLALLVGGLATGFLAGLLGIGGGGVLVPVLFETFTFLDVPESIRMHLVLGTSFAVIVPTAISSFRAHRSKGAVDMDVLRRLAPFVIAGVLVGIALVSVVSGSALKWVWVVCGYILAIKMALGREDWRIASDVPNNVPIRIAAFSIGLVSTLMSIGGGMFLVALFTLCGWSILKAVATSSGFGPIIAVPGLIGYVWAGWGNPELPAMSLGFVSLIGAAIIIPMSVLAAPIGVRVAHGISRRALELAFAAFLALVATRLLVSMM
>NC_022997.1|WP_023787741.1|2502877_2503489_+|hypothetical-protein
MALAKQSANSGTFGRRGVDASPRVRPASVRKPTVSGRPEARTAEAAAQAADAIARDVGTAASRGKAYAYACLSGATTFLAVLFILSGVESRFFQSGPMLFLLAIPVLPTLALALYIPTVVLSDLARLLSIPRGWSDIGIGFVLGLGVGIAYAVTAADAKSLATAVAITAGGIVGGWAFWRAQGYPGLSRAGRDAAEIAYHKIK
>NC_022997.1|WP_023787740.1|2501251_2502751_+|phosphomannomutase/phosphoglucomutase
MFPKPRADLVPNTADFERLPLVKPTGFREYDARWLFPNEINLMGLNAVGLGMARVFDEYGVAKRIVVGHDYRWYSASVKQALMTGLLAGGFEVFDIGLALSPMAYFAQFELDVEGVAMVTASHNDNGWTGIKMGLARPLTFGPDEMGRLKEIVLSGDFAPSDGGRYHFLPDLAERYMKDLADRPRLKRPLKVVAACGNGTAGAFAPKVLEAVGCEVVPLDAELDHSFPRYNPNPEDMKMLHAIAEAVVANGADVGFGFDGDGDRCGVVDNEGHEIFADTVGVMLARDIAAIHKNPVFVADVKSTGLFATDPVLQEAGAKTLYWKTGHSYMKRYTFEQKALVGFEKSGHFFFQPPLGRGYDDGLVAALAVCDMLERAEGKTIADLRRALPKTYQSPTMSPHCDDEKKYGVVERVVADYEALAKNGGTVAGQKIRDLVTVNGVRVTLEDGTWGLVRASSNKPELVIVVESPVSEENKIAMFRDIEARLAAFPEVGDYNQKI
>NC_022997.1|WP_023787739.1|2500474_2501047_+|TIGR02281-family-clan-AA-aspartic-protease
MALSSGARSLLSELASWGAAAGILVVGVLYYDTLRTALSDAIGLGSEPVVAEAVATREPAGEPNTLRSGTEELKASRDGHYYARAEINGRPLDVLVDTGASMVALTYEDAERLGLNLRPSDFTARVQTANGTAAVAPVELDRVSIGRITVRNVRGVVSERGRLGKTLLGMSFLGELRRVDISQGRLLLVE
>NC_022997.1|WP_023787738.1|2499678_2500392_+|TIGR02281-family-clan-AA-aspartic-protease
MLAVLLAILAALVVVFWSLSGDSGSLLAEAGDRWPYALAMLALVGLYLAFLSGDYRGRAREALRHAGAWLGLALLLIVGYSYREDLRAVAYRVAGEVLPPGHSILVSTSPSGELAVRIRRQENGHFVARGTANGVALSMLVDTGASTVVLKPADAERIGIDVQNLSFTTPVSTANGTAYAAPVRLRTISVGPLEVRDVDALVSQPGALNENLLGMSFLKRLRSYEFSGDFLTLRGTS
>NC_022997.1|WP_041316502.1|2509266_2510100_+|hypothetical-protein
MKASGGRAAMGPAANVVSNTEGAMVYDSATKQMKVCDGTQWLDIGNGDASTMVPNWPDALNCSSAAGSTSIVTLIATSAGSPGVYGYNAGANDVGYQVQFNNDGSWHSIINTAGWGNVAGCTGKTIAQLYAEGRAFNFVGGGGVPSGAVMAFDATACPSGWTEYTPARGRFLRGIDNGAGNDPAGTRAPGHTQADELTNHNHTATAANAGAHAHTLVHGNFGTLGSGTGGAMMSSNQGGMGGGTNTTGDHTHTITVANTGGAETRPKNVAVLFCRKS
>NC_022997.1|WP_023787749.1|2510510_2512472_-|cation-translocating-P-type-ATPase
MGMSDRIEWISVGLSALALVGVMVGFAGVHVGVESLASTGFGLVYLAGGLPATWRAVVELWRERTLDIDLLMVIAALAAAAVGAPAEGAILLFLFSVSTTLETLAMGRARREVAALVALRPETALRRTALGGIEEVRISGLRVGDVLVVRPGAKIPVDGVILSGDGHLDESNVTGESMPVRKAAGAKVFEATVNHSAVLEMRVTATSGDSTIARMIRLVTEAQAARAPSERFSAWFGQRYTVAVLVGSTLILAVLLGLGREWNEAIYRAAVVLVAASPCAIVISVPAAILSALSASARGGVLFKGGAALESFAAVTQFAFDKTGTLTTGRPEVTAIVSPVMPEDEFLRLLAGLEAHSEHGIAAAVRREAERRALTPADMADVTAHPSEGITGRDAAGMVWAGNPRMVARMGGDISGAAFNAITAGAETVIWMGRDTSVLGAVTVADAVRGTSREALDALREAGTTRITMMTGDRRPVALRVGKELGLSAEDIEADLLPHDKVRLVDAMTRAGKVAFVGDGVNDAAALARADVGIAMGAAGSDVAVQAADVALLSEDMARLAAAHKLARRTARIIRQNLTFAIGAMLVLVSGALLFELPLPLAVVGHEGGTVLVVLNGLRLLFDPIRGDGRSSKASAEARKIEAQVSRELQSES
>NC_022997.1|WP_023787750.1|2513138_2513555_+|hypothetical-protein
MIVTHTRNAQGHRRIYLGGKASIECWIEPAADGIAWSFHMDTAPTTYPQPDDTMRAWAKHVLLELAAEVGAEPDDLKAVPFERIAALHTANPADFGRAPAPRRQAYAHAFMTTPPNITRPSADFTGKDFTSQRRQTAR
>NC_022997.1|WP_023787751.1|2513559_2513988_-|hypothetical-protein
MTLFLDTEFNGFGGALISIALVSDNGGRESEFYGVRELPDQLAPWVEANVLPVLGKKPEPDTVLRRRLVEFLHGHAGQTIIADWPEDLIHCLGLLCPSPGRAYRINLNLRLIKATEELPSEVPHNALSDARALMRWYQSGAT
>NC_022997.1|WP_023787752.1|2514435_2514789_+|plasmid-mobilization-relaxosome-protein-MobC
MPRRGYRKGLDDAKEPLPCYVRIRLAEASFVTLSAEASTRGITVSALARLILTAHLKAQRAELPRRRGTDAALLRQFIRIGNNLNQLTRQANAGLVAVSADELHTCLDRINTLARAL
>NC_022997.1|WP_023787753.1|2514792_2515875_+|relaxase/mobilization-nuclease-domain-containing-protein
MLAKIAPPANDFHALARYLVRGKSGNPHPKRVAWVFTQNLPTDDPELAAKYMEATAQLSARTRKAAYHLMIAWHANERPTPEAMQDVARQTLQLTGLAEHQALVMGHGDKPHPHLHILLNRVHPDTGRAWKTSQDFARLDRIMRELADAHGFAFVPAHTFNPDVTDTLPQLPDSPATYAGKRGAPTLRPQWSKAQARVMGERLSEDLTMDATPEDMQDILAQHGVALETKGKGHVVGNAHGYAKLSSLGLTASAKHLARAVDALPSQLQYFTPSERHRSTVFDVDAVDIARAFHSIGLLTKEDVRAAIDDARVQRQQRRPQWQSSVLGLSTALTNVAPRPARPQRRFSSPGKPNKPAKAR
>NC_022997.1|WP_144083586.1|2515912_2516179_+|hypothetical-protein
MPAMSRTDAINAIAKNLPRLREDELATLVAVTTAWAQPERTVSLTPAERDAVERSRKDFAAGRTLTLDEAEARTDEYLAARRAARNGE
>NC_022997.1|WP_023787755.1|2516175_2516487_+|hypothetical-protein
MRSIRVSRTFNDQLNALLAYGEERFGRAVAEEKKTLVYAIIRDHLAWFPASHIRDPELGLHFYPVTHTPFTLVYDFDEAELRIHFVLHQRADRGSLDPGDVAW
>NC_022997.1|WP_023787756.1|2516604_2517219_+|hypothetical-protein
MAATEPQPHGNFIAFLVREKEPGDKRPMFEGRLSLPDEPKVEYAFPLFGHEYTDPKTGEVMTMFNGSTDPVSLNAAPMDQIAALLKGADTTTALASVGSLQLRPRQLVLFPNRFKDEAPEKDRPHYWGAYNHTRNDAVLRIGAWLRKDRYGRAMFGGATSYPLPGKSEVEQQDATLTIAELEAQGVVSRGMPEKAKKRSGGRGE
>NC_022997.1|WP_023787757.1|2517972_2519490_-|PLP-dependent-aminotransferase-family-protein
MPLPLRLQPTSPVSLQTQIFEQVRAMILEGRLRPGERLPATRTLSEQIGIARNTAALAYERLTAEGYIETRSSVGTFVSFQIPESALYAASQNSPPSARKPRRAIGSPVNPTFRCQAVVNPHRGRLVADFWVGRPDPDSFPRKTWAQLIVKRLRTAGSDLTEYRAQSGLFDLRRAIADRLRPTRNIATNADEIVIVGGCQDGLSLVSRLMLGPGATAVVEQPCYQGAAFLFESFGANVVSVPVDDRGLDCSLLPDVRNAVAYVTPSHQYPLGVTLSLERRLELLAWAAETDSYILEDDYDSDFRFHGAPIAALKGLDRTGRVIYLGTFSKSLGAGLRLGYVVFPPELVERARDMKTLMNNGQPWLEQATLADFMTSGGYERHVRRIRKLYLSRRNALLAALEKHFPGGEIIGDEAGMHLAWRLPSSFPPAREIEQRAIEAGVGVYTLTSGAAVGFDTSPENDRYLVLGFSSLTEREIAAGIARLAEALAPVTDRKHRPKRLVVEC

Crispr_ID: NC_022997_8

• CRISPR_ID: NC_022997_8
• CRISPR_location: 2622313-2622428
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_022997_8

Consensus_repeat	Method
CGTGCTGGAAGCACGCCTCCGGCATGAA	CRISPRCasFinder

spacers of NC_022997_8

>8.1|2622341|60|NC_022997|CRISPRCasFinder
CCAGACGGGCAAAAGAGCCGCGCGGCTCCGCCGTGAGACAAGATTGATCGATGGCGGCGT

CRISPR arrays and Neighbor proteins around NC_022997_8

CRISPR arrays

The CRISPR arrays of NC_022997_8

>merge|NC_022997|8|2622313-2622428|CRISPRCasFinder
CGTGCTGGAAGCACGCCTCCGGCATGAACCAGACGGGCAAAAGAGCCGCGCGGCTCCGCCGTGAGACAAGATTGATCGATGGCGGCGTCGTGCTGGAAGCACGCCTCCGGCATGAA

>NC_022997|8|7|2622313-2622428|CRISPRCasFinder
CGTGCTGGAAGCACGCCTCCGGCATGAA	CCAGACGGGCAAAAGAGCCGCGCGGCTCCGCCGTGAGACAAGATTGATCGATGGCGGCGT
CGTGCTGGAAGCACGCCTCCGGCATGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_023787847.1|2618578_2620813_+|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl|CDD|273955
NC_022997.1|WP_023787858.1|2626238_2626793_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023787844.1|2615007_2616276_-|phage-portal-protein	unknown	unknown	gnl|CDD|227039
NC_022997.1|WP_023787854.1|2623910_2624258_-|DUF1491-family-protein	unknown	unknown	gnl|CDD|369334
NC_022997.1|WP_023787852.1|2623219_2623501_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl|CDD|226079
NC_022997.1|WP_023787846.1|2617561_2618155_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023787853.1|2623516_2623816_+|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl|CDD|274228
NC_022997.1|WP_081717722.1|2620819_2621488_+|DUF1214-domain-containing-protein	unknown	unknown	gnl|CDD|227689
NC_022997.1|WP_023787843.1|2614221_2614941_-|HK97-family-phage-prohead-protease	unknown	unknown	gnl|CDD|273682
NC_022997.1|WP_041318612.1|2612942_2614187_-|phage-major-capsid-protein	unknown	unknown	gnl|CDD|273690
NC_022997.1|WP_023787856.1|2625301_2625652_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023787855.1|2624314_2625010_-|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|274897
NC_022997.1|WP_023787841.1|2612150_2612741_-|phage-head-tail-connector-protein	unknown	unknown	gnl|CDD|274035
NC_022997.1|WP_023787859.1|2626859_2627357_-|chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl|CDD|119330
NC_022997.1|WP_023787845.1|2616303_2617656_-|DNA-packaging-protein	unknown	unknown	gnl|CDD|227633
NC_022997.1|WP_023787857.1|2625794_2626223_+|SufE-family-protein	unknown	unknown	gnl|CDD|376883
NC_022997.1|WP_041318607.1|2611824_2612130_-|phage-head-closure-protein	unknown	unknown	gnl|CDD|377521
NC_022997.1|WP_023787860.1|2627562_2627895_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023787851.1|2622559_2622751_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023787849.1|2621490_2622111_+|hypothetical-protein	unknown	unknown	gnl|CDD|227723

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_023787847.1|2618578_2620813_+|PBP1A-family-penicillin-binding-protein	gnl|CDD|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_022997.1|WP_023787844.1|2615007_2616276_-|phage-portal-protein	gnl|CDD|227039	COG4695, COG4695, Phage-related protein [Function unknown].	2.18468e-113
NC_022997.1|WP_023787854.1|2623910_2624258_-|DUF1491-family-protein	gnl|CDD|369334	pfam07372, DUF1491, Protein of unknown function (DUF1491). This family consists of several bacterial proteins of around 115 residues in length. Members of this family seem to be found exclusively in the Class Alphaproteobacteria. The function of this family is unknown.	1.67469e-35
NC_022997.1|WP_023787852.1|2623219_2623501_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl|CDD|226079	COG3549, HigB, Plasmid maintenance system killer protein [General function prediction only].	3.56412e-30
NC_022997.1|WP_081717722.1|2620819_2621488_+|DUF1214-domain-containing-protein	gnl|CDD|227689	COG5402, COG5402, Uncharacterized conserved protein [Function unknown].	1.16042e-34
NC_022997.1|WP_023787843.1|2614221_2614941_-|HK97-family-phage-prohead-protease	gnl|CDD|273682	TIGR01543, Putative_prohead_protease, phage prohead protease, HK97 family. This model describes the prohead protease of HK97 and related phage. It is generally encoded next to the gene for the capsid protein that it processes, and in some cases may be fused to it. This family does not show similarity to the prohead protease of phage T4 (see pfam03420). [Mobile and extrachromosomal element functions, Prophage functions, Protein fate, Other].	1.71573e-37
NC_022997.1|WP_041318612.1|2612942_2614187_-|phage-major-capsid-protein	gnl|CDD|273690	TIGR01554, prophage_Lp3_protein_18, phage major capsid protein, HK97 family. This model family represents the major capsid protein component of the heads (capsids) of bacteriophage HK97, phi-105, P27, and related phage. This model represents one of several analogous families lacking detectable sequence similarity. The gene encoding this component is typically located in an operon encoding the small and large terminase subunits, the portal protein and the prohead or maturation protease. [Mobile and extrachromosomal element functions, Prophage functions].	4.93574e-126
NC_022997.1|WP_023787855.1|2624314_2625010_-|peptidoglycan-binding-protein	gnl|CDD|274897	TIGR03979, His_Ser_Rich, His-Xaa-Ser repeat protein HxsA. Members of this protein share two defining regions. One is a histidine/serine-rich cluster, typically H-R-S-H-S-S-H-R-S-H-S-S-H. Members are found always in the context of a pair of radical SAM proteins, HxsB and HxsC, and a fourth protein HxsD. The system is predicted to perform peptide modifications, likely in the His-Xaa-Ser region, to produce some uncharacterized natural product.	1.1576e-06
NC_022997.1|WP_023787841.1|2612150_2612741_-|phage-head-tail-connector-protein	gnl|CDD|274035	TIGR02215, conserved_hypothetical_protein, phage conserved hypothetical protein, phiE125 gp8 family. This model describes a family of proteins found exclusively in phage or in prophage regions of bacterial genomes, including the phage-like Rhodobacter capsulatus gene transfer agent, which packages DNA. Members of this family show some similarity to members of pfam05135, a putative DNA packaging protein family. [Mobile and extrachromosomal element functions, Prophage functions].	1.2106e-48
NC_022997.1|WP_023787859.1|2626859_2627357_-|chromosomal-replication-initiator-protein-DnaA	gnl|CDD|119330	cd06571, Bac_DnaA_C, C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.	1.62823e-26
NC_022997.1|WP_023787853.1|2623516_2623816_+|HigA-family-addiction-module-antidote-protein	gnl|CDD|274228	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family. Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other].	2.05926e-36
NC_022997.1|WP_023787857.1|2625794_2626223_+|SufE-family-protein	gnl|CDD|376883	pfam02657, SufE, Fe-S metabolism associated domain. This family consists of the SufE-related proteins. These have been implicated in Fe-S metabolism and export).	1.21822e-62
NC_022997.1|WP_041318607.1|2611824_2612130_-|phage-head-closure-protein	gnl|CDD|377521	pfam05521, Phage_H_T_join, Phage head-tail joining protein.	7.15062e-25
NC_022997.1|WP_023787845.1|2616303_2617656_-|DNA-packaging-protein	gnl|CDD|227633	COG5323, COG5323, Uncharacterized conserved protein [Function unknown].	4.08293e-152
NC_022997.1|WP_023787849.1|2621490_2622111_+|hypothetical-protein	gnl|CDD|227723	COG5436, COG5436, Predicted integral membrane protein [Function unknown].	8.4266e-15

Protein sequences

>NC_022997.1|WP_023787849.1|2621490_2622111_+|hypothetical-protein
MLKKLWARVTNINVPLVAAALFASAILHILATLATPLFTPTSAYDRLARALPANTMHLLPEVAPGAQPLPFLSSDARYAVCHFDTSDGAVSLSAVLPEPGWMLALYSPQGEAFFTSVGTPVRRTEVSLMIVPGEDIWRMGARPTGLVTGLTNRGTLTTVSRDSMLTIPANEGIAVLRAPDQGEAYRNRTLAELGRALCEPSKGRTS
>NC_022997.1|WP_081717722.1|2620819_2621488_+|DUF1214-domain-containing-protein
MLRSGVLRSRSASNLMGFTLHRLKKRLAAAVAYTADWALFIGVVLILGLGSSWYMIERGSPLTTLTAGPWVSWVSAARVDSDPYTRAHEARLGILPLSTEIAQTFIARTDSEGRALHSSCDYAVEGHELPTHWWSLTVFDAQGRLIPNTLGRSAYTSDTMAIRGNGTFLATLSRDAHPGNWLPIGGAGRLALVFTVLDHGSRSLTQGEEVVPFLPAVTRKDC
>NC_022997.1|WP_023787847.1|2618578_2620813_+|PBP1A-family-penicillin-binding-protein
MSDWFFKRGRRTGIDWMSLDSRLDSALSDLWSFCKDVWDACSSFFARFKLTGWRRLLAEAGSESLTLSLGGFFVLYALALPAFLDFDEARFFTGRYSVTFLDAAGNEIGQRGILHNDAVPLEEIPDAVVHATLATEDRRFFEHFGVDVIGTTRALIENLRANDVVQGGSTLSQQLAKNLFLSSERSLDRKIKEAFLALLLETRFTKREILKLYLDRAYLGGGAFGVEAASQFYFGKSVREVNLAEAALLAGLYKAPTSYAPHVNLPASRARTNEVLQNLVDAGYYTAAQAHEARLNPAQIVETRTATSPDWFLDWAFEEIQRLMAGKNQYVLTARTTVDLTMQKQADEALVSFLKQNGRRLRMNSGAIVAMETDGAVRALTGGPDYGESQFNRATHARRQPGSSFKIYVYAAALENGYKPSSMVRDTSRSCGRWHPQNYGGSRGSGARMPLSMALARSLNTTAAELSFAVGREKVIELTQRLGITGIRKTCSMALGDYGFPPIQHVGAAAVFANGGMSATPYGILDIVNSRGELIYDRARDEPERERLVSQEVAEGLNQMMHQVVTSGTGQRAALDFTHVVGKTGTSTGPRDVWFLGFTGKYVGSVWLGNDDNRPMANGNTGGQLAAPLWASFMSVAHRSMNIPTIPGLQPHPVQIAEQQRIAELKRTDPAAAAALSGARRAPSLTMSTPARDALKRITSELRRAAGVAEPEPASTPGPSAPASRTSGDRADLGPVRAPSATIP
>NC_022997.1|WP_023787846.1|2617561_2618155_-|hypothetical-protein
MQLDDETWADVRRAYEDGTAPLKEIAARFDVTPQRIGVRAKKEGWDGRERSRRPARLKEKKPQPVTGAAQAAEESGRGKTPALRRTVLPTRGAQRALIGRLYRAISLKLEHMEMRMASGEARSAQDEERESRALATLISNFEKVTEAVADLDRDKDAARGTGRVGADAERMRREIAERLERLGGVGPAGRPSGKSRS
>NC_022997.1|WP_023787845.1|2616303_2617656_-|DNA-packaging-protein
MRSACAAKLRSVLSASAASGLLADHLASLDRESLSFILADWQIWARDDQLPPGQTRTGGDWRVWLILGGRGAGKTRAGAEWVRAKALGIPPLGAERASRIALVGETLADVRRVMIEGVSGLLAIHGDNERPAFEVSKSQLVWPNGSIAQMFSAEDPNSLRGPQFDAAWCDELAKWRYAEETWDMLQFGLRLGTAPAIAVTTTPKPLPLLKSIMSDPATAITRAATAANAAHLAPAFIAEMERRYAGTALGRQELLGEIVDEQSGSLWRRDWIEQARVAVCPELRNIVVAVDPPVTATARSDACGIVVAGIGADGRAYIAADRTLQGRSPDVWARAAVRAYHEFMADRVVAEVNQGGDLVVSVLRQIDEAVAVRKVRATRGKWLRAEPVAALYAEGRVAHVGVHAILEEQMLAFGADGLSRGRSPDRVDALVWALTDLMIERTAQPGIRQL
>NC_022997.1|WP_023787844.1|2615007_2616276_-|phage-portal-protein
MPRILETLAGLWPGRAKPSAALPSANEAKASAAGPLIVLETLGRPVWTPRDYEAFAREGFMQNAIVYRAVRMISEAAASVPLLLYEGDAEIEQHPLLDLLARPSVDHTSADFLESWYGYLLVSGNGYVEAVAVDGKLRELYALRPDRMKVVPGGEGWPEAYEYTCAGRTVRFDEEPIEGVRPILHVRLFHPANDHYGMSPVEAAAQAIDIHNTAGRWNKALLDNSARPSGALVYGGADGRMTPEQFERLKAELDDGFQGPQRAGRPLLLEGGLDWKPLSLSPKDMDFVEARNGAAREIALAFGVPPMLLGIPGDNTYSNYQEAQRAFWRGTVLPLVVRTAKAMSSWLAPAWETARPSVPSMHGERRLELRPDLDQIEALTSEREALWARIERVSFLTQNEKRAAVGYAPLETEAIADLPSEE
>NC_022997.1|WP_023787843.1|2614221_2614941_-|HK97-family-phage-prohead-protease
MGASQANRTTTRGGVPAPAPEMKFVSLDFKHTEADGTFEGYASLFNREDLGRDVVMPGAFRESLASRGPRGVKLLFQHDSNQPIGVWTVLREDARGLYAQGRLMREVSKAREVMALMRAGALDGLSIGFRTVKARRDKASGVRRIDKIDLWEISIVTFPLLPEARITTTKQKPFASGPPTEREFERWLTRDAGLTRGEARAVLRSGLSGLKALRDAGGGMTTEAQLAARMREAAIALRS
>NC_022997.1|WP_041318612.1|2612942_2614187_-|phage-major-capsid-protein
MADHDDIETKAGGSVSAAFEDFMRAFEAYKETNDERLGEIERRSASDPLIDERLARIDRAIDETKRTADRLALKAERPHIGGGAPETGAVREHRQAFHAYVRKGDAAGLHLLEQKALAVSTNSGADGGYLVPPETERAVMSALKNISPIRAIASVRQVSGSVYKKPFSTTGFAHGWVAETTARTQTSTPTLVEIPFATKELYAMPAASATLLDDSAVDIDAWIAEEVQGTFAEQEGKAFVSGNGTTEPTGFMSYTKELAGDEEWGEIAYIKTGVNGAFPAENPSDKLIDLVYTLKAGYRANGTFVFNRGTQAAIRKMKDDDGTYLWQPAAAAGEPSLLMGYPVIESEDMPAIASGAYAMAFGDFRRGYLIVDRVGIRVLRDPYSAKPYVLFYTTKRVGGGVQDFNAIKLLRFAE
>NC_022997.1|WP_023787841.1|2612150_2612741_-|phage-head-tail-connector-protein
MALTLMGAPAVEPVSVSAAKAHLRIDGDAEDILIASLIVTSRLHVEAALGLALISQEWRLTLDKWPEPRSSKNAAVRFPLRPVHSIEEVRVRGADGTPDVLPPERYLLDQDALTPRLVPNGESWPAPGLPVSGIEIDFEAGMGAEAEEVPEPIRHAILLLVAHWYEHRDPMEIGSAGAAIPHAVSDLLKPYREVRL
>NC_022997.1|WP_041318607.1|2611824_2612130_-|phage-head-closure-protein
MRHRLGLEEPVDTADGGGGATRVWSLVAEVWGAVEPLSGSERIEANGIQGRVSHEIWVRHRAGLGPHMRFKMGTRIFEIRAVIDSGERRRVMRCLVEERVP
>NC_022997.1|WP_023787851.1|2622559_2622751_-|hypothetical-protein
MASILEFRSLPANAKPRSTADGTRGTADIVLFPGVRYERMTEDAEPAQKPRGRARRDRLELDG
>NC_022997.1|WP_023787852.1|2623219_2623501_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MIKSYRNAMTEAVARGKAPKGFPADLARRALLRLLALDHAKTLDDLRSPPGNRLEALKGDRKGQHSIRINAQWRICFVWTEAGPEQVEIVDYH
>NC_022997.1|WP_023787853.1|2623516_2623816_+|HigA-family-addiction-module-antidote-protein
MNKSILPPIHPGEYLREEFLVPLKLSPGALAKRLGVPRTRIERIAAEQTGITTDTALRLAKFFKTSPEFWISMQTGYDLKIAEKALKTQLDQIEEMSAA
>NC_022997.1|WP_023787854.1|2623910_2624258_-|DUF1491-family-protein
MRLKSEIWVKAYVRRLASAGQQAYVVRHGDDDAGAIYIRINLLDGTSCLFGPAPASLSGAETDRRWVGHFKGEARADMEVDASLEREARTDPDLWIVEVESRNGAHGLEGWLTDA
>NC_022997.1|WP_023787855.1|2624314_2625010_-|peptidoglycan-binding-protein
MTPTSVRLGVLAFTLLTGALATNMFILQPPGRQIAGLDSARQPGVVEAARTPQSGRSAAAPNAVVPPLAIETGAVRPLAGASDTSDLTRAIQRELKAQGYETGAVDGVPGLVTRGAIMAYESDANLPLTGEPRHALLQHIVLGSAEIAPADRTRPAAPGPEAEAVIRAVQNAFRQLGYMTTVPNGRLNEETRRAIRKFETERNLRETGRISGELLARLATLAGDALRTAER
>NC_022997.1|WP_023787856.1|2625301_2625652_+|hypothetical-protein
MSLFRIAIVLSLGVAVMPSDRAQQEELYTRAASAAHWTMTFCDRNGRTCEVSAGLWDAFLKKAEFAGKLVYDVALHTAGPEDTSLKAIPASSEGRGTLSPRDLEPDWRGAPQEHGI
>NC_022997.1|WP_023787857.1|2625794_2626223_+|SufE-family-protein
MTLQNLQSDFELLDDWEDRYRYIIELGRTLAPMPDALKTEATKVRGCTSQVWLVSETDGTSGEAEPTLRFIGDSDAHIVRGLIAILFALYDGKPAKDILSTEPETVFNALGLKEHLTPQRSNGLASMVERIRTDARAALEIG
>NC_022997.1|WP_023787858.1|2626238_2626793_-|hypothetical-protein
MRPKRARKVRAPLADRVGPGRNASESPLAWLFNRRDRDGNPLIGEAEFNAGERLRADFWFAQMSPNVTQSWSVTASTGSGRRGAHAADQADNVIAAAERVRRALDAVGPELAGILIDVCGHLNGLEEIERRARWPQRSAKLVLGIALSALARHYGLISEAPAAPRTARVRHWGANDYRPAIDAG
>NC_022997.1|WP_023787859.1|2626859_2627357_-|chromosomal-replication-initiator-protein-DnaA
MSLRSGIEQGHSTLHALFRDIDGDAVEPWFGRGRASGWENWRCGAPAPQGRPSAGEAARLRRIIEGAIGDIFGVPQADLSKPSRGKAPVALARQVAMYVAHVACGLSLTQVGQIFARDRTTVAHACAVVEDKRDDPVFDRALELMEWIVPAMVGQSLSMASFNSA
>NC_022997.1|WP_023787860.1|2627562_2627895_+|hypothetical-protein
MRSEFRARLSDVDTQRSVEERADELARLVPLWPSEIADTSRAGRTRIVAKLYRALKAERQRGVGGHWTYDLARHAALLAAWRRERAALALHDAANRCGARKPQRKRAPAR

Crispr_ID: NC_022997_9

• CRISPR_ID: NC_022997_9
• CRISPR_location: 2786449-2786538
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_022997_9

Consensus_repeat	Method
GTCCGCCCCCTTGCGCGCGGGGGGCAGAT	CRISPRCasFinder

spacers of NC_022997_9

>9.1|2786478|32|NC_022997|CRISPRCasFinder
CTGATGGCGACGAGCGTGCCGGACCCGTACCA

CRISPR arrays and Neighbor proteins around NC_022997_9

CRISPR arrays

The CRISPR arrays of NC_022997_9

>merge|NC_022997|9|2786449-2786538|CRISPRCasFinder
GTCCGCCCCCTTGCGCGCGGGGGGCAGATCTGATGGCGACGAGCGTGCCGGACCCGTACCAGTCCGCCCCCTTGCGCGCGGGGGGCAGAT

>NC_022997|9|8|2786449-2786538|CRISPRCasFinder
GTCCGCCCCCTTGCGCGCGGGGGGCAGAT	CTGATGGCGACGAGCGTGCCGGACCCGTACCA
GTCCGCCCCCTTGCGCGCGGGGGGCAGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_081717734.1|2797296_2798391_+|diguanylate-cyclase	unknown	unknown	gnl|CDD|143635
NC_022997.1|WP_023788012.1|2794419_2795937_+|glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|237027
NC_022997.1|WP_023788010.1|2792599_2792794_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023788004.1|2785332_2786247_+|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl|CDD|223461
NC_022997.1|WP_144083596.1|2781756_2781990_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_041316570.1|2788920_2790267_-|sorbosone-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|225044
NC_022997.1|WP_041318720.1|2777924_2778266_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023788007.1|2790641_2791187_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023788005.1|2786848_2788411_+|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|234864
NC_022997.1|WP_041316568.1|2782564_2783035_-|MaoC-family-dehydratase	unknown	unknown	gnl|CDD|239538
NC_022997.1|WP_023788002.1|2782314_2782404_-|pyrroloquinoline-quinone-precursor-peptide-PqqA	unknown	unknown	gnl|CDD|178960
NC_022997.1|WP_041318727.1|2780669_2781671_+|DUF1775-domain-containing-protein	unknown	unknown	gnl|CDD|377951
NC_022997.1|WP_023788011.1|2793077_2794343_+|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl|CDD|223411
NC_022997.1|WP_081717860.1|2776952_2777645_-|DUF1194-domain-containing-protein	unknown	unknown	gnl|CDD|369046
NC_022997.1|WP_023788009.1|2792072_2792459_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_023788013.1|2796026_2796815_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NC_022997.1|WP_023787999.1|2778366_2780592_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NC_022997.1|WP_051388559.1|2783074_2784313_-|patatin-like-phospholipase-family-protein	unknown	unknown	gnl|CDD|132847
NC_022997.1|WP_023788003.1|2784517_2785249_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|366006
NC_022997.1|WP_023788008.1|2791188_2792076_+|ParA-family-protein	unknown	unknown	gnl|CDD|224113

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_081717734.1|2797296_2798391_+|diguanylate-cyclase	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	5.34618e-60
NC_022997.1|WP_023788012.1|2794419_2795937_+|glycerol-3-phosphate-dehydrogenase	gnl|CDD|237027	PRK12266, glpD, glycerol-3-phosphate dehydrogenase; Reviewed.	0
NC_022997.1|WP_023788004.1|2785332_2786247_+|PhzF-family-phenazine-biosynthesis-protein	gnl|CDD|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	5.16118e-90
NC_022997.1|WP_041316570.1|2788920_2790267_-|sorbosone-dehydrogenase-family-protein	gnl|CDD|225044	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism].	1.24592e-84
NC_022997.1|WP_023788013.1|2796026_2796815_-|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	9.16958e-55
NC_022997.1|WP_023788005.1|2786848_2788411_+|2-isopropylmalate-synthase	gnl|CDD|234864	PRK00915, PRK00915, 2-isopropylmalate synthase; Validated.	0
NC_022997.1|WP_041316568.1|2782564_2783035_-|MaoC-family-dehydratase	gnl|CDD|239538	cd03454, YdeM, YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function. YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase. Other enzymes with this fold include the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.	5.13144e-71
NC_022997.1|WP_023788002.1|2782314_2782404_-|pyrroloquinoline-quinone-precursor-peptide-PqqA	gnl|CDD|178960	PRK00284, pqqA, pyrroloquinoline quinone precursor peptide PqqA.	0.000637658
NC_022997.1|WP_041318727.1|2780669_2781671_+|DUF1775-domain-containing-protein	gnl|CDD|377951	pfam07987, DUF1775, Domain of unkown function (DUF1775). Domain found in bacteria with undetermined function. Its structure has been determined and is an immunoglobulin-like fold.	1.76132e-58
NC_022997.1|WP_023788011.1|2793077_2794343_+|Glu/Leu/Phe/Val-dehydrogenase	gnl|CDD|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
NC_022997.1|WP_081717860.1|2776952_2777645_-|DUF1194-domain-containing-protein	gnl|CDD|369046	pfam06707, DUF1194, Protein of unknown function (DUF1194). This family consists of several hypothetical Rhizobiales specific proteins of around 270 residues in length. The function of this family is unknown.	1.0706e-62
NC_022997.1|WP_023787999.1|2778366_2780592_+|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	2.00344e-57
NC_022997.1|WP_051388559.1|2783074_2784313_-|patatin-like-phospholipase-family-protein	gnl|CDD|132847	cd07208, Pat_hypo_Ecoli_yjju_like, Hypothetical patatin similar to yjju protein of Escherichia coli. Patatin-like phospholipase similar to yjju protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins, and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	1.67734e-23
NC_022997.1|WP_023788003.1|2784517_2785249_+|NUDIX-hydrolase	gnl|CDD|366006	pfam00293, NUDIX, NUDIX domain.	0.000264484
NC_022997.1|WP_023788008.1|2791188_2792076_+|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	4.49761e-31

Protein sequences

>NC_022997.1|WP_023788004.1|2785332_2786247_+|PhzF-family-phenazine-biosynthesis-protein
MALTYHILDVFTDRRFGGNPLAVVLGADGLTDGQMQAIAGEFNLSETVFVLPSERPAHSAKVRIFTPRSEVPFAGHPTIGTATLLAGLQAPPASNGEADALVILEQNIGTVRVGVRLREGAPAFAEFDAPKLPAEAGVLPPIDILAAGLGLMPSEVGFENHKPICFAAGNTFAFVPVSSLDAIRRARINGAHWERAFDQQGVIGVYLYTRQCEHTGHAFHVRMFAPQVGVPEDPATGSAAVCLAGVVQHFDGLPDGTYKRIVEQGYEMGRPSQIALTLVVSGGKLTSVRTGGASVRVATGTLEV
>NC_022997.1|WP_023788003.1|2784517_2785249_+|NUDIX-hydrolase
MGQQIEARLIEATRVDLRVTDAEWAFARQYQGEIAAHWARRSAENPHYFNGTVLLLSDYALSDDGVVSGRLLRTDFMSFLYWRETGCPEAGIYDTFCTALIRSREGHVLLCQQRPGNLNEGFATPPGGFIDERDVDADGTIDLSRAVTREIAEETGLGAPLLRQGAGFAILLVRHQVSLAVPWHSDLSGDDLVRKASLHIAGEAEGELLRTLSLSPGEALRTLSLPDYARVLLSASDVLKTSA
>NC_022997.1|WP_051388559.1|2783074_2784313_-|patatin-like-phospholipase-family-protein
MASPDVSRLAAARVRAKALAAMLAGLFIATTLTACATLDRLPAVPLALASEIQPLDIPYARFYADGDPAVLEALARETVAKRRAHTKATGAARSRADTTTFLAISGGGDDGAFGAGLLVGWTARGDRPDFAVVTGISTGALSAPFAFLGPEYDHALRSVYTETKVDDIFVKVSLISVFEGDGATDTTPLRNLIARFVDHKMVRRIAEEYDKGRLLLIGTTNLDQARSVIWNIGAIAKSSDPRARDLIIEVLRASASIPGVFPPVMLDVAVGGKHYQEMHVDGGATTQMFLYPPQLHLKRVERADPNHKDVAYIIRNGRLFRDEETVKRRTLAVASQAISTMIASNAVNDLYRIYLTTHRDGVAFNLAYLDDGFTVPYKGPFDKEYMNKLFAYGYRKGAGDVRWHKTPPGYAD
>NC_022997.1|WP_041316568.1|2782564_2783035_-|MaoC-family-dehydratase
MTGKDAETRLYFEDLEVGRRFTTGSVTMELDAIKAFAASFDPQPFHLDEEAASASFFGGLVASGWHTASVTMRLLVTSGLPIAGGVIGAGGDIVWPRAVRPGDTLSVVSEVVAAKPSASRPERGMVTVRSETLNQDGEVVQIMTARLVVPTRGSAR
>NC_022997.1|WP_023788002.1|2782314_2782404_-|pyrroloquinoline-quinone-precursor-peptide-PqqA
MKTWMKPSVREQEVGLEVTSYLPADIDII
>NC_022997.1|WP_144083596.1|2781756_2781990_-|hypothetical-protein
MSYSATPPTSSPQPSSNVTYLPLKPRVVETVERGAARPVPFDPGWTEELERRRRAVARWRGSDVALKETMMRTSRWI
>NC_022997.1|WP_041318727.1|2780669_2781671_+|DUF1775-domain-containing-protein
MKRSYSSQALAAFALLPLALLASGPAGAHVTLEQREAAPGAAYKAVLKVPHGCGTSPTQAVRVEIPEGFINVKPMPKPGWSLATVKGPYATSYPLHGRTLTEGVKDITWADGNLPDEHYDEFVAAGFLGKDLAGGSSLYFKVTQTCADGERQWIEIPDGTEGQKLASPAAVLRIAASHEHAVPKDTGGAAKIGTLAIQGAWARATPQGAKVGAGYLTILNTGSEADTLIGIAAPVAGKGEIHDMTMTDGVMRMRALPEGIEIPAGGTATLAPGGKHLMFMDLKEPLVSGASLPVTLTFKSGASVEVTFPIRPIGGDQKGGGAAKDEHDHHHHH
>NC_022997.1|WP_023787999.1|2778366_2780592_+|TonB-dependent-receptor
MTSPFRPVSRRHISPARGTYSLAAIGTVVLAIHAWPASAQETELPEITVTTTAAQPKAPRPKQAAAAPSGVPVPQSPSADTPAGAPVSPGTRSGSLTVPTTAEAVAEIQRTPGAVEIVPADAYAASTPAVTIKDALDYVPGVFVQPKWGEDARLSIRGSGISRNFHLRGTQLFMDGIPISTADGFGDFQEVDPTVYRYIEVFKGANALRFGANSLGGAINFVMPTGYDAHRFTARTDIGSFGFRKFSSSSGGVSGPVDYFIAGTWQEWDGYRDHSWGESLRGSMNLGYRLSENVETRFYVNANDVEQRIPGAVTRQTALTDPKQAAAVNVLNDWQRNIETLRIANKTTVRLSQGTLLEFGAFNVDRHLDHPIYQWLDYRYDDYGGFARLSDDSVIAGFRNRFIAGVNLHNGTVDVRHFGNGPNAAKLALISHTENRSENLSVYAENSFFVLPDVALVAGLQFLHADRDRDVFFGNEQSGRNTFDVWSPKAGIVWDVDPGWQMFANISRSAEVPSFGENAVSGSAFTAKLQEATTYEIGTRGRRETYHWDIALYRAEIDNELQCLTILVPFPNMCTVTNADKTVHQGLELGFGAAVLHSLIVDGPTPDRLWLNAAYTLNDFHFDNDAVWGDNELPGLPRHFLRAELMYRHPSGVFFGPNVEWAPSAYFVDNANTLKTEGYAIWGAKLGYEGETFTAYIEGRNLSDTAYIASASVSGNVLGLDGAYFEPGTGRAIYGGVQVKW
>NC_022997.1|WP_041318720.1|2777924_2778266_+|hypothetical-protein
MLIALAFRSLVPDGFMIAAANAGDGSFEIVICTSTGQKTMHVAADGTTPAEQQGEPDLCPFAFSSVGDVATGEPDLAGTVAYASLTYKLAAALYAETPKPGATSARGPPNLLI
>NC_022997.1|WP_081717860.1|2776952_2777645_-|DUF1194-domain-containing-protein
MATLSGLRAQFADAQAYVDTALVVSVDVSNSVDAHRYKLQMEGIATALEDPEVLKAILNGPNASILFSMVTWADRPRQVIAWERISSPAEAAAVANMVRKLPRQTGEFTCVSAMLRAISDKVVSQIPAKPFRTIVDVSGDGRENCNPDEDPAAVRDELAALGVTVNGLPILEADEGDTLEQWYRENVMGGPGSFVLPADGFDDFGRAIRQKFIMEISSGVPAYKQASRRN
>NC_022997.1|WP_023788005.1|2786848_2788411_+|2-isopropylmalate-synthase
MTTETKDVAGDRVVIFDTTLRDGEQCPGATMTFDEKLDVADLLDAMGVDIIEAGFPIASEGDFEAVTAIAKRVKRATVAGLARAINADIDRAGEAVRHAQRGRIHTFVSTSPIHLAHQMRKSEAEVLEIITATVTRARNLVEDVEWSAMDATRTGIDYLCQCVDAAIKAGATTINLPDTVGYATPEEYAAMFRAVRERVPDSDKAIFSTHCHNDLGLAVANSLAALDAGARQIECTINGIGERAGNAALEEIVMAIRTRSDALPYRTGIETTMLARASKLVSAVTNFPVQYNKAIVGRNAFAHESGIHQDGMLKHQQTYEIMTPESVGVAKTSLVMGKHSGRNAFRTKLKELGYEFGENAFEDAFNRFKALADRKKHVYDEDIEALVDQSIAHAHDRMKVVALQVVAGTSGPQSATLTLDIDGNQQTVHANGNGPVDATFAAIHKLVPHTARLELYQVHAVTEGTDAQAEVSVRLSEDGRVVTGRGADTDTLVASAQAYVAALAKLMLKRQKTAKAEQAV
>NC_022997.1|WP_041316570.1|2788920_2790267_-|sorbosone-dehydrogenase-family-protein
MKGDPIMRALLQSAILAPVRALSARAGASSPPIEVTYGANPTLSEPERPWIPIPHVNEMKAVGWTEDGAPVAADGLSVTRFADGLIHPRWVHALPNGDVLVAEASSLPLSNKGIVGAVMEPVMRNAGAVQETSPNRIVLLRDADGDGVAELREIFLEGLHQPFGMALLDGYLYIANTNALVRVPYSDGDLTAAGPPETVASLPFRADDNGHWTRNVIAAPDGSRLFVTVGSISNIAEQGMDVEQGRAMIHAIDPATGRVTAFATGLRNPNGMGFAPGTSTLWTVVNERDGLGDNLPPDYLTSVQEGGFYGWPWAYWGRADHRFKSEEIPAGAIERTIKPDYALGGHTAALGLVFNEKPALGSQWQGGAFVGMHGSWNRREPSGYCVIYVPFTNGKPSGMPVDVLTGFLDANNNAMGRPVGVEIAGDGALLVADDVGKVIWRVAPAVAR
>NC_022997.1|WP_023788007.1|2790641_2791187_+|hypothetical-protein
MLEKDLYPLVQVYLNIAFSPRLGPMFGDFRPLSAVTANSGGNTTGVWSKPDLCLVALWRQKYGLHWHLDVHGFEVKPLGKCSTQSVYEALNHTSLVHYSHLMWHCSDWDERDQTCHSVLEACSRFGVGLITFSDPGDVRSYEIRVPAHKHAPTPDALDEFLETRLEASDRKQLQSWIQELQ
>NC_022997.1|WP_023788008.1|2791188_2792076_+|ParA-family-protein
MAIRVAIGNPKGGVGKSTTAMMLAEGVALRFGARVLVLDMDPQAMATKILIGQQALHEYRSQDRGLSSLLNAWAKGRKADISRHIVPASDIIELRDRSNDIGSVDIIPSDPELLKDLGELQTIIGRVRRKQRVDALLATMFAEELSRIDRSYHLIIFDCPAGPVPLALTSFRLSNHVIVPTNLEQNSYSTLVDFWRLILSEDLGLSERLRVHILVTMYQSINPVQRQMLDHVRAGAYELNAVYRAIPHSTALQRAQMHPGTGAFRSAREKYEGAIDEVFALADTMFDRLELEGAP
>NC_022997.1|WP_023788009.1|2792072_2792459_+|hypothetical-protein
MSDGLKITPETALERIFTVIREEASANPAFARRMLEAAGVTVTFTGAVAAQMADPILVASRSDYPAFREAFMTFSEKELKDLAKNFALATQEQIKSVKTKPKAAGLVDLLWEGANRKLAERRLRGSSP
>NC_022997.1|WP_023788010.1|2792599_2792794_+|hypothetical-protein
MPRPKKKNEHLPYGEGQREQYGEGFAYRKHDLSKGADKVNDLGGFAGGARPKKSVPDPEEPEGD
>NC_022997.1|WP_023788011.1|2793077_2794343_+|Glu/Leu/Phe/Val-dehydrogenase
MSHDNLLDQALVRLDEAAAHLSIDPDVIEKLKYARETAKARLMIRMDDGSRKSFIAWRCRYDDTRGPTKGGIRFHPDSDVFEVETLAFWMTFKCAVMNLPYGGGKGAVRVDPRKLSKAELERLSRAYMQAFARVIGPNRDIPAPDVYTNAMIMGWMADEYAQIVGQTEPAVITGKPIALGGSLGRDDATARGGYYLVRHLATDLGLGQGARVAVQGFGNAGQHIASLFAADGHKIVAVSDSSGAVKCDSGLNLQKLFAAKASGQSVSSTAGEDGHELMSADDLVGVDCDILAPSALENMIHEGNAAQVKAKIVLELANGPVTSEADAILEKNGIVVLPDILANAGGVTVSYFEWVQNRQGFYWTIEEIHDRLKTIMEREGRAIWDISREKNISMRTAAYVHALGRLAEAIEAHGTQSFFTS
>NC_022997.1|WP_023788012.1|2794419_2795937_+|glycerol-3-phosphate-dehydrogenase
MSGTIYDLAIIGGGINGAGIAADAAGRGLRVVLFEKGDLACGTSSASSKLIHGGLRYLEQREFRLVRHALAEREVLLDRAAHLIHPLRFVIPHAAGMRPRIVMRAGLFLYDSLARRRRIPASASVDLTRDPMGAALRPEFRNGFSYHDCWVDDARLVAITALDAAERGAHILTRAPVTRIVREGEGWRIDAEAGGARHAFSARAVVNAAGPWCADVAALARPEGAGSKAAVPMLRLVRGTHIVVPRIPGADDALLLQNADGRVVFVLPFGARFTMIGTTEVVVSTPAEGFVASAEEEAYLIEAAGRYLSHPLTRTDIVWRFAGVRPLVDDGAATASSVTRDWRLDLVQPAGSAPFLNVIGGKITTFRLLAEAVLDRLRPFFPGMGGAWTAHAPLPGGDVGPHGLTGYRADLARRRPGFAPETLDRLAALYGTRADRVIGDAAHDADLGAALGGGLTEREICYLRDTEWARTAEDVLWRRTKAGLDLSAGERPEAEAKIARLVSRT
>NC_022997.1|WP_023788013.1|2796026_2796815_-|SDR-family-oxidoreductase
MDLDLAGKTALVTASSGGIGLEIARSLAAEGARVTINGRSEAAVGKAIEDVRKTHPAADLVPLVADNGTAEGCAVTIAAIPAADILVNNLGIYEAVGFFDETDEAWQRLFEVNVMSGVRLARHYLKGMIDRGKGRVVFISSESGISPAPEMAHYSATKTIQLGISRSLAELTKGTRVTVNSVLPGPTRTEGVEKFISGVYPGLDFAEAERRFMAENRPSSLIARLIDPKEIGDVVSFVCSERASAINGSNIRAEGGLIRSAF
>NC_022997.1|WP_081717734.1|2797296_2798391_+|diguanylate-cyclase
MNSSPDLSRSQQGILAVGAGVLGAAIVALLAISDFDLTPIRTLRSVHVGGGGTIISTQYNPFAILAIALVGLAIVGAFAWLIARFAPLLASASFASIGGTSSAVARAGQRIERELSKVLELIRGHISSNESYAKSLANAQSRLSELSEGEQVRVIVSLLVAENERMRRDSSELKVKLEESQRQIETLRSNLIEAEEVVLRDPLTGVGNRRCFDIEIEKAIADSRDSGAPLSLVMCDIDHFKRVNDDFGHQVGDEIIKMFSRVIEASVRDGDTVIRYGGEEFAIILPKAGQDVAKSIAERIRRQFESKKLTVRETNQKIGQMTASFGVAEYRSGDDTELLVQRADTKLYDAKSGGRNQVSTYGDN

Crispr_ID: NC_022997_10

• CRISPR_ID: NC_022997_10
• CRISPR_location: 2855612-2855694
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_022997_10

Consensus_repeat	Method
TAGGGTCCAAAGCGATCATGGTCT	CRISPRCasFinder

spacers of NC_022997_10

>10.1|2855636|35|NC_022997|CRISPRCasFinder
CTTGAGTTAGACCTATGATTCACGCTTCGGACTGA

CRISPR arrays and Neighbor proteins around NC_022997_10

CRISPR arrays

The CRISPR arrays of NC_022997_10

>merge|NC_022997|10|2855612-2855694|CRISPRCasFinder
TAGGGTCCAAAGCGATCATGGTCTCTTGAGTTAGACCTATGATTCACGCTTCGGACTGATAGGGTCCGAAGCGATCATGGTCT

>NC_022997|10|9|2855612-2855694|CRISPRCasFinder
TAGGGTCCAAAGCGATCATGGTCT	CTTGAGTTAGACCTATGATTCACGCTTCGGACTGA
TAGGGTCCGAAGCGATCATGGTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_023788055.1|2848547_2849432_+|phosphatidate-cytidylyltransferase	unknown	unknown	gnl|CDD|366491
NC_022997.1|WP_023788058.1|2852670_2854995_+|outer-membrane-protein-assembly-factor-BamA	unknown	unknown	gnl|CDD|274514
NC_022997.1|WP_081717738.1|2841780_2843631_-|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NC_022997.1|WP_041318761.1|2846300_2847029_+|UMP-kinase	unknown	unknown	gnl|CDD|239787
NC_022997.1|WP_023788064.1|2859824_2860328_+|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl|CDD|234568
NC_022997.1|WP_051388560.1|2856087_2857782_-|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|313331
NC_022997.1|WP_023788069.1|2862785_2863583_-|ATPase	unknown	unknown	gnl|CDD|227677
NC_022997.1|WP_041318764.1|2847850_2848537_+|isoprenyl-transferase	unknown	unknown	gnl|CDD|184840
NC_022997.1|WP_023788051.1|2845122_2846073_+|elongation-factor-Ts	unknown	unknown	gnl|CDD|236491
NC_022997.1|WP_023788067.1|2861909_2862173_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_041316576.1|2844006_2845002_+|30S-ribosomal-protein-S2	unknown	unknown	gnl|CDD|183428
NC_022997.1|WP_023788056.1|2849583_2850843_+|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl|CDD|235472
NC_022997.1|WP_023788065.1|2860320_2861127_+|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase	unknown	unknown	gnl|CDD|235390
NC_022997.1|WP_023788053.1|2847134_2847698_+|ribosome-recycling-factor	unknown	unknown	gnl|CDD|178850
NC_022997.1|WP_174394677.1|2863579_2864281_-|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319835
NC_022997.1|WP_023788066.1|2861215_2861734_-|pilus-assembly-protein-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379302
NC_022997.1|WP_023788063.1|2858708_2859761_+|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	unknown	unknown	gnl|CDD|234858
NC_022997.1|WP_023788068.1|2862298_2862829_+|MgtC/SapB-family-protein	unknown	unknown	gnl|CDD|224204
NC_022997.1|WP_023788057.1|2850940_2852359_+|RIP-metalloprotease-RseP	unknown	unknown	gnl|CDD|182723
NC_022997.1|WP_144083603.1|2857945_2858461_-|NfeD-family-protein	unknown	unknown	gnl|CDD|224501

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_023788055.1|2848547_2849432_+|phosphatidate-cytidylyltransferase	gnl|CDD|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	1.10417e-41
NC_022997.1|WP_023788058.1|2852670_2854995_+|outer-membrane-protein-assembly-factor-BamA	gnl|CDD|274514	TIGR03303, OM_YaeT, outer membrane protein assembly complex, YaeT protein. Members of this protein family are the YaeT protein of the YaeT/YfiO complex for assembling proteins into the outer membrane of Gram-negative bacteria. This protein is similar in sequence and function to a non-essential paralog, YtfM, that is also in the Omp85 family. Members of this family typically have five tandem copies of the surface antigen variable number repeat (pfam07244), followed by an outer membrane beta-barrel domain (pfam01103), while the YtfM family typically has a single pfam07244 repeat. [Protein fate, Protein and peptide secretion and trafficking].	0
NC_022997.1|WP_081717738.1|2841780_2843631_-|GGDEF-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	5.14255e-62
NC_022997.1|WP_041318761.1|2846300_2847029_+|UMP-kinase	gnl|CDD|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	2.12888e-138
NC_022997.1|WP_023788064.1|2859824_2860328_+|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl|CDD|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	1.2942e-91
NC_022997.1|WP_051388560.1|2856087_2857782_-|outer-membrane-beta-barrel-protein	gnl|CDD|313331	pfam10082, BBP2_2, Putative beta-barrel porin 2. This domain is a putative beta-barrel porin type 2.	6.32668e-114
NC_022997.1|WP_023788069.1|2862785_2863583_-|ATPase	gnl|CDD|227677	COG5387, COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase [Posttranslational modification, protein turnover, chaperones].	1.6753e-74
NC_022997.1|WP_041318764.1|2847850_2848537_+|isoprenyl-transferase	gnl|CDD|184840	PRK14830, PRK14830, undecaprenyl pyrophosphate synthase; Provisional.	7.48415e-122
NC_022997.1|WP_023788051.1|2845122_2846073_+|elongation-factor-Ts	gnl|CDD|236491	PRK09377, tsf, elongation factor Ts; Provisional.	3.63775e-129
NC_022997.1|WP_041316576.1|2844006_2845002_+|30S-ribosomal-protein-S2	gnl|CDD|183428	PRK12311, rpsB, 30S ribosomal protein S2.	0
NC_022997.1|WP_023788056.1|2849583_2850843_+|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl|CDD|235472	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	0
NC_022997.1|WP_023788065.1|2860320_2861127_+|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase	gnl|CDD|235390	PRK05289, PRK05289, acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase.	3.24393e-149
NC_022997.1|WP_023788053.1|2847134_2847698_+|ribosome-recycling-factor	gnl|CDD|178850	PRK00083, frr, ribosome recycling factor; Reviewed.	6.30355e-99
NC_022997.1|WP_174394677.1|2863579_2864281_-|HAD-IA-family-hydrolase	gnl|CDD|319835	cd07533, HAD_like, uncharacterized family of the haloacid dehalogenase-like (HAD) hydrolase superfamily, similar to Parvibaculum lavamentivorans HAD-superfamily hydrolase, subfamily IA, variant 1. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	3.3569e-81
NC_022997.1|WP_023788066.1|2861215_2861734_-|pilus-assembly-protein-N-terminal-domain-containing-protein	gnl|CDD|379302	pfam13629, T2SS-T3SS_pil_N, Pilus formation protein N terminal region.	9.82062e-19
NC_022997.1|WP_023788063.1|2858708_2859761_+|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	gnl|CDD|234858	PRK00892, lpxD, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional.	5.50815e-148
NC_022997.1|WP_023788068.1|2862298_2862829_+|MgtC/SapB-family-protein	gnl|CDD|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	1.10272e-36
NC_022997.1|WP_023788057.1|2850940_2852359_+|RIP-metalloprotease-RseP	gnl|CDD|182723	PRK10779, PRK10779, sigma E protease regulator RseP.	2.25345e-78
NC_022997.1|WP_144083603.1|2857945_2858461_-|NfeD-family-protein	gnl|CDD|224501	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	1.08375e-25

Protein sequences

>NC_022997.1|WP_023788058.1|2852670_2854995_+|outer-membrane-protein-assembly-factor-BamA
MLWLALAVPAALTIDVVAFSAPAHAQTIRDIRVEGNRRVEPETVRSYLQFTVGEAYDAGKADRSIQALFATGLFADISIDRQGDAVVVYVVENPVINQVAFEGNSEVDTDTLRSEVHLKPRSVYTRARVQADVQRILDVYRRQGRYAAWVEPKIIELEQSRVNLVFEINEGGATKVQGINFVGNYAFSDAQLRDIISTTQSGLFDFLKGTSIYDPDRMNLDRELLRQFYLKNGYADVRVVAANAELDRGGSGFYLNFAIDEGERYAFGDVTIESSLPEVNPHYLSGEVLTRQGDIYNGQDIEKSTERLTLLIAEQGYAFARVRPRATPDPASRTIALSYLIDEGPRVYIERINVNGNLRTKDHVIRREFRLAEGDAFNPLLVDRAKKRLEALGFFKKVDIKRRPGSSPDRVILDVDLEEQSTGELSFGAGYSTSEGVIGDVSISERNLLGNGQFLRLRLAGSMERMQVDLSFTEPRFLDRNLSAGFDLFHKELDYARETGYESKRTGGTVRLGFPLSENLWMQTGYTIDYSSMDVDDRWGDQVSLVVRDEVADLGEGALTSSIGTSITYDKRNHPRTPTSGYYLQVATDMAGLGGDVQYVRVNAEGRAYYPITEKITFVGRLIGGHIEGWGDDDIRLTDLYYRGGETIRGFDRAGFGPRDMSANGREDALGGRSYWAGTAEVRFPLPFVPDDLGLSAAVFADAGSLFNANERAKRLDQAGLIDLADDSTIRSSIGASIMWNSPVGPIRMDFAKALSKESYDEVQFFRFGASTNF
>NC_022997.1|WP_023788057.1|2850940_2852359_+|RIP-metalloprotease-RseP
MIEGLLSQVSTWTIQGLGFLFVLSAVVFFHELGHFLVARWCGVTVTTFSIGFGKELAAFVDRKGTRWRFAAIPLGGYVKFLDDTNVASSPGTAASAEMSPEARAGTFHDKPVWQRFLVVAAGPLANFILAAVIYTALNVSTGVSRVTAQVDEVVAGMPAEQAGLRAGDVITRIDGWRIETFDDVSRLVLTSSGRTLQIAVERNGETLTFPVTPAMRDERDDLGVTVRLGDIGVRRHVPARVGAVVPDSAAEKAGIEVGDVITAIDGTAISSFRDVVELVQPAAERPLAVTVKRGNETRALEIVPTAAEIAMPDGSTKQVGRIGVAQDRPEPVAVSFVEAARLGVRETYSNIVQTITGIGDIIWGRQSADQVGGPILLAEVTARVVEHGWEPLLRLTALISANIGLLNLLPIPVLDGGHLVFYTIEAIRRRPLSQRVQEIGFKIGIALVMTLIIFVNLNDLMRLGKRWLFGGG
>NC_022997.1|WP_023788056.1|2849583_2850843_+|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MAHAPPVSRASAFETETADASAEATAHAPGTRRPQRLSVLGATGSIGTSTLDLVGRHPDRFEIVALTAQCNAARLAELAIAHRAQLAVIGDPAYYDDLKSHLAGTGIRVAAGADAVEAAALEPADCVMAAIVGAAGLTPTFAAAGQGCRVALANKECLVSAGDIFLRHVRQSGAELLPVDSEHSGAFQSIGQTQAASIEKIVLTASGGPFRTLDRHALARVTPEQALKHPNWSMGAKVTIDSATLMNKGLELIEAYHLFPVEAHQLEAIVHPQSVVHCLVMLEDGSVMAQLSQPDMRTPIALALSWPERLTTPVSRLDLLALKTLSFEAPDLDRFPALGIATDALRHGGAAPAVLNAANEVAVAAFIDRKIGFLDIAQTVASCLEKAESLGLLSSVETLEDVLAVDLEARNMARMLLPG
>NC_022997.1|WP_023788055.1|2848547_2849432_+|phosphatidate-cytidylyltransferase
MTEDETRRAEPEPAIAASGGAKAELGLRIVSALLLGSVSVALAWAGTLPFAALVLAVTLILSWEWAHVVRGDGIDLALGIQFAAAIGAIGLAAFGFAALGVALLLIGTIIVLALEFGERPILSAAGVLYAGLPAVALIWLRSNEPMGFYAVLFILLVVAATDTAAYFAGRSIGGPRLAPSISPKKTWSGLLGGISAAGLTAGAFASSVGAPVLPLAVAGVAMGLVAQTGDLAESALKRAFHLKDASGLLPGHGGFMDRVDGLVPVAVLLALVLLFLDPKAPADALFSGLFPAQR
>NC_022997.1|WP_041318764.1|2847850_2848537_+|isoprenyl-transferase
MDGNGRWAAERGLPRAAGHKAGVEAVRRTVKAAIELSIPCLTLYSFSSENWSRPRDEIDYLMGLMKRFIRGDLAELHQNNVKILVIGERSDIDQEMLALIDEACDLTRDNTRLTLTIAFNYGARNEITRAAQRLAEDVAAGRLSPSEITVDHFRLALDTGDLPDPDMLIRTSGERRLSNFLLWQSAYTELVFLDAYWPDFGRELLIEAITQYNSRERRFGGLPSRSTA
>NC_022997.1|WP_023788053.1|2847134_2847698_+|ribosome-recycling-factor
MSLTTFDPTEIETRMRASLEALKRELAGLRTGRASAHLLDPVQVTVYGSRMPLNQVATVTVPEPRMISVQVWDKSNVSAVEKGIRESNLGVNPIIDGTTLRLPIPAPTAERRQELAKQAHKYAENHRVAVRNVRREGMELLKKLEKDGKIGEDEQHKNSAKVQELTDKLIKEIDQTLAAKDAEIQKV
>NC_022997.1|WP_041318761.1|2846300_2847029_+|UMP-kinase
MTTGDGALKYRRLLVKLSGEALMGQNGYGLDTAVVDRLAADLAGALAEGCEVSVVVGGGNIFRGLQGAARGMDRATADYMGMLATVMNALALQSALEAAGAPARVLSAITMPTVCEPYVRHRALYHLERKRIVIFAAGTGNPFFTTDTAATLRAIEMGCDAVAKATQVDGVYSADPKKDPAAQRYDRLSYSDVLAKDLRVMDGAAIALARDNHLPVIVFSIDEPGNLIKVLRGTARATVIHG
>NC_022997.1|WP_023788051.1|2845122_2846073_+|elongation-factor-Ts
MSTISAALVKELRDKTGAGMMDCKQALTETNGDMEAAIDLLRKKGLAKAAKKSDRVAAQGLIGVISKVKSGAVVEVNSETDFVARNAEFQELVQTIAGLAAEAGGDLQKLLTAAYPGGKGTVDDRMKEAIATIGENMAVRRTASLAVNDGVVADYVHSKAADGLGKIGVLVALESAGDTDKLMALGRQIAMHIAASSPQVVNVEDLSQDAMDRERAIYLEQAKAEPKNAGKSDEILLKAGEGRLQKEFVNQAVLLKQVFVIDGKATVAEILKQAEKDVGAPVKVAAFVRYQLGEGIEKKEEDFAAEVAKTMGAVKQ
>NC_022997.1|WP_041316576.1|2844006_2845002_+|30S-ribosomal-protein-S2
MTAPQFNMRQLLEAGVHFGHQAHRWNPKMASFIYGARNNIHILDLTQTVPMLHQALNKVSDTVASGGRVLFVATKRQASDAIADAAKRSAQYYINHRWLGGTLTNWKTISTSIRRLRQLDDILADPQGRTKKEVLTIQRERDKLDKALGGIKDMGGVPDLLFVIDTNKEGIAIKEARKLGIPIVAIVDTNCDPDGIDFPVPGNDDAGRAITLYCDLIARAALDGIERGQGSSGIDIGAAVDAPAESLPEAAVAFKGIEGPRGEADDLKRIKGVNEKIEQKLNDAGVFHFWQIADLDADNLAALDRQLKLKGQIGEENWVAQAKKLVEASAA
>NC_022997.1|WP_081717738.1|2841780_2843631_-|GGDEF-domain-containing-protein
MFGSSVHLLRESNGGAIFLDRVRQAVDAALQPITDIRSGATHGCEALARQTQALGFASIPQFFAFAERLGVRVEVDAFLVGRAAQKIAARKAHVDALLFVNLDRMRAAQIEDTLPAFLAELSRAGLSPSDVCIEITEGGEAPSCVGLIQAVAELRQHGFRIAIDDFGTGHSGLQALYELQPEYVKIDRFFIKDLDRDGRKRVFVSRVVELAHILGTQVVAEGVERVEELHACRDAGCDLVQGYFVAMPSTEAADIRSVYGPVSENPDRRLAPRNVVTLEAEGVVMALEALPDTTRVADVVDYFLGHPECAYRPVVDARRMPLGIVRERDLRWLVQSPFGRDLLQNSSFPMTLRDFTTRLPTVDASICPTQLIEQCAHAIDEGVIVTEGTRYSGFVPSNALLRLAGMIRLRQAQSQNPLTHLPANDAILGFIGRATEERGLSHAFAHLDFNHFKPFNDVYGFHVGDRAIIMFADLLRAEFGRDDVFIGHIGGDDFFVGVSGEIDGFSRRVRDVCTRFALNAESLYTQQHRQNGYIECAGRDGVVARFPLLTCSVALLVLPKGGRAATTDEIAHELSRLKTISKKSEACFSTATLTVRECGNVFNARETPALLERAAN
>NC_022997.1|WP_051388560.1|2856087_2857782_-|outer-membrane-beta-barrel-protein
MAVVWRLGLIVFGFAAATLVAALSYAPPASAQELNEPPRTNAGAASARSITAPSGRDRDPVSDLANAYEFVSPARMRGSIGGADDDDGEQGGDPLDSDPLSAETDGAASTSESTGESEALQPVDGLTPSDGRIELGESEAWNEGADLGRDTRPPEDLDVFNTPPAGHDPLLFQIEDIDPAETDRRPARFARIEPYDPVGIRIGSFVLFPEAELGGLYTSNVLSTPRARSDIAGELRTEARLVSNWNVHAVELRGTTFSTYHDDYPSEDDRAWSVEARGRLDISRRTNFQGLVGRSVSQEDRTAVDANVTGERAQVRSDEARLAFNHRFNRLAVELRGSVSDTTYALPHDGESLADRDTLETHQAVRASWELKPTLAVFAEGELNQRDKKAAPADGIRRDSDGVRTRVGLDFGSTGAILRGQASVGYGRQTPRDGRLASVEAFLFDANLAWRPSEITSLMLTASSDIYDTTTEESGGVVSHKVGIEARHAFRRHLIGSAGLSYTHYDFHRTPIEESVVTAFVGAEYYASPELVLFARYQHLSFASNDVNGDYETDEVRVGVRVRR
>NC_022997.1|WP_144083603.1|2857945_2858461_-|NfeD-family-protein
MPAFIDLFLGFGLWNWFIAGLVLMALEAVIPGVQFLWFGLSAIVVGLILTLLTWAGVGEAMTLPWQLVLFATVSVATVFAVRFFSDHQTVDRADLTLNQRAAQYIGRVVVVEEEIRGGRGRVRVGDTLWAAAGADTPQGTRVRIAGGRGHRPGRRARLTRVPANSALCQSP
>NC_022997.1|WP_023788063.1|2858708_2859761_+|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase
MNHPGFFRKAGPFTLAEVAAATGAEVQGETGQADRLVDDVVPLSEAGSGQLSFFENRKYLPQLLATQAGACLVDPRFLPRVPAGTVALTTPTPYQAFAKSLLLFYPEAMHSKAAEGGTEERIARSAVIEDGAIIEPGAIVGPEARIGRGTRVAAGAVVGYRVTIGRDCYIGPLVSVIHALIGNRVILHAGVRIGQDGFGFAMGRTGHLKVPQVGRVIIQDDVEIGANSAVDRGALKDTIIGEGTKIDNLVQIGHNAVIGRHCVIVGQVGIAGSAELGDFVVMGGQSGAIGHIKIGTGAQIAGGSHPKGDVPPGAVLAGTPARPFRQWAREVAAVQRLARRSIDDDDADGK
>NC_022997.1|WP_023788064.1|2859824_2860328_+|3-hydroxyacyl-ACP-dehydratase-FabZ
MDDATKQALPKTADIGKILKLLPHRYPFLLLDRIYDINGDETCVGVKNVTINEPFFQGHFPQYPVMPGVLIIEGLAQTAGALCVHSLGEDYKTELVYFMGIDKCKFRKPVVPGDQLHYHVRKIRNRGRVWRFYGEAKVDGQTVAEAEISAMLADTADARAFAASKNG
>NC_022997.1|WP_023788065.1|2860320_2861127_+|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase
MADTNIHPTAIVEDGATLADGVTVGPFSIVGRDVSLGEGVVLHSHAVVTGRTTIGARTRIFPFASIGHQPQDLKYHGEPSTLSIGTDCMIREGVTINPGTEGGGMSTTVGNGCAFLANSHVGHDCHVGNNVIFSNNVMLAGHVEVGDFAILGGGAAVIQFARVGDHAFLGGMSGLEQDLIPYGMALGNRAYLSGLNIVGLKRRGFSASQIHDLRRAYRLMFAAEGTLLERVDDVAQEFRDHPTVMEIIAFIRAGGKRSMCTPKNAADA
>NC_022997.1|WP_023788066.1|2861215_2861734_-|pilus-assembly-protein-N-terminal-domain-containing-protein
MLPTHALFARQTWQARRAVTMALGAFLAGGALTLAPAHAADLVVAYDQSQLLRLPRTVSSVIIGNPSIADVTVQGGNLLVVTGKTFGITNIIALDGERNIIQDQRVIVTRDEVRTVNLNKAGERQSYTCTPNCSPMLTIGDEKDYFSTISSHAQTKTRISEGTSGSGGAEGQ
>NC_022997.1|WP_023788067.1|2861909_2862173_+|hypothetical-protein
MSRPTVLIAVAALAVVLVGMIVIAQDRGPSPVTGGAETRVDAPGTRVESDNTGTTVNAPGTSVDTNESGTRIQAPGVDITVPRRDND
>NC_022997.1|WP_023788068.1|2862298_2862829_+|MgtC/SapB-family-protein
MTSLELLHSTGLLAHLEVGFRLLLAAALAGLLGWDREEQARPAGLRTYMLVALAAAVFTVITFEIYETVRQSQMQANADPIRIIEAVTAGVAFLAAGVIIQGRNTVRGLTTGAGMWMAGALGVAAGTGNYLLAIIAALLAFGILKLAHFAQPQPDVPRRPTLIIETVEDEDTERRP
>NC_022997.1|WP_023788069.1|2862785_2863583_-|ATPase
MTEDERKSANGSANGQGKEPMTVPVKDALRPPLPKRFYKSASVESRDGAFAILLDGRPVRTPGKRLLAVSVIALAEAVAAEWEAQGERIDPATMPLTRLANTAIDAVSDKMHEVADDIAAFAASDLLCYRAEAPEGLVRRQAEAWDPPLAWARDALGAGLTVQAGLMPVDQPAEAIASVRGALAPLDALSLAATHVLTTLTGSAILALAHVEGRLTLEEVWAAATVDERWQSDLWGRDAEAEARMAERLAEATAAARCLRLLRSR
>NC_022997.1|WP_174394677.1|2863579_2864281_-|HAD-IA-family-hydrolase
MSSARPPVKLVIFDCDGTLVDSQHMIVAAMTDAFASQGRVAPPRESVVGVVGLSLDWAIARLVPEETDPVVIERLSEAYKEAFRERRLGPDHTEPLYDGVRDVLDRLAAREDVSLGIATGKSRRGLDAVLEREGIVHHFRTIQTADTHPSKPHPSMIFAAMSEAVAEPVDTVMIGDTTFDIEMALGAGTSSIGVAWGYHPVDALRAAGAHHVTADCAELGRTLDRLMFERQVG

Crispr_ID: NC_022997_11

• CRISPR_ID: NC_022997_11
• CRISPR_location: 3336956-3337039
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_022997_11

Consensus_repeat	Method
GTCGCCTTGCTCCCGAGCCCCTTCGGGG	CRISPRCasFinder

spacers of NC_022997_11

>11.1|3336984|28|NC_022997|CRISPRCasFinder
GCTGTTTGTTCGGCGGCACTGGCCGCGT

CRISPR arrays and Neighbor proteins around NC_022997_11

CRISPR arrays

The CRISPR arrays of NC_022997_11

>merge|NC_022997|11|3336956-3337039|CRISPRCasFinder
GTCGCCTTGCTCCCGAGCCCCTTCGGGGGCTGTTTGTTCGGCGGCACTGGCCGCGTGTCGCCTTGCTCCCGGGCCCCTTCGGGG

>NC_022997|11|10|3336956-3337039|CRISPRCasFinder
GTCGCCTTGCTCCCGAGCCCCTTCGGGG	GCTGTTTGTTCGGCGGCACTGGCCGCGT
GTCGCCTTGCTCCCGGGCCCCTTCGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_022997.1|WP_023788505.1|3339101_3339356_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_041319075.1|3327287_3329228_-|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl|CDD|235836
NC_022997.1|WP_023788497.1|3329579_3330212_-|NADH-quinone-oxidoreductase-subunit-J	unknown	unknown	gnl|CDD|235844
NC_022997.1|WP_023788504.1|3337065_3338913_+|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl|CDD|236382
NC_022997.1|WP_023788511.1|3343713_3344862_+|carboxynorspermidine-decarboxylase	unknown	unknown	gnl|CDD|143502
NC_022997.1|WP_041319081.1|3334051_3335335_-|NADH-quinone-oxidoreductase-subunit-NuoF	unknown	unknown	gnl|CDD|237441
NC_022997.1|WP_023788499.1|3330853_3331921_-|NADH-quinone-oxidoreductase-subunit-NuoH	unknown	unknown	gnl|CDD|235692
NC_022997.1|WP_023788498.1|3330350_3330839_-|NADH-quinone-oxidoreductase-subunit-NuoI	unknown	unknown	gnl|CDD|235637
NC_022997.1|WP_023788509.1|3343013_3343415_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_144083628.1|3345840_3346044_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_051388882.1|3341558_3342836_+|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_051388878.1|3325721_3327275_-|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl|CDD|235622
NC_022997.1|WP_023788506.1|3339638_3339959_+|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|234669
NC_022997.1|WP_023788502.1|3335345_3336050_-|NADH-quinone-oxidoreductase-subunit-NuoE	unknown	unknown	gnl|CDD|237082
NC_022997.1|WP_081717766.1|3346213_3347608_-|glutamate--cysteine-ligase	unknown	unknown	gnl|CDD|178221
NC_022997.1|WP_023788500.1|3331940_3334055_-|NADH-quinone-oxidoreductase-subunit-G	unknown	unknown	gnl|CDD|236387
NC_022997.1|WP_023788503.1|3336265_3336613_-|hypothetical-protein	unknown	unknown	unknown
NC_022997.1|WP_158412876.1|3345003_3345729_+|hypothetical-protein	unknown	unknown	gnl|CDD|366292
NC_022997.1|WP_023788507.1|3340140_3341355_+|saccharopine-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|224662
NC_022997.1|WP_023788496.1|3329239_3329548_-|NADH-quinone-oxidoreductase-subunit-NuoK	unknown	unknown	gnl|CDD|180218

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_022997.1|WP_041319075.1|3327287_3329228_-|NADH-quinone-oxidoreductase-subunit-L	gnl|CDD|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
NC_022997.1|WP_023788497.1|3329579_3330212_-|NADH-quinone-oxidoreductase-subunit-J	gnl|CDD|235844	PRK06638, PRK06638, NADH-quinone oxidoreductase subunit J.	1.38211e-66
NC_022997.1|WP_023788504.1|3337065_3338913_+|DNA-polymerase-III-subunit-gamma/tau	gnl|CDD|236382	PRK09111, PRK09111, DNA polymerase III subunits gamma and tau; Validated.	0
NC_022997.1|WP_023788511.1|3343713_3344862_+|carboxynorspermidine-decarboxylase	gnl|CDD|143502	cd06829, PLPDE_III_CANSDC, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase. Carboxynorspermidine decarboxylase (CANSDC) catalyzes the decarboxylation of carboxynorspermidine, the last step in the biosynthesis of norspermidine. It is homologous to eukaryotic ornithine decarboxylase (ODC) and diaminopimelate decarboxylase (DapDC), which are fold type III PLP-dependent enzymes that contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain, similar to bacterial alanine racemases. Based on this similarity, CANSDC may require homodimer formation and the presence of the PLP cofactor for its catalytic activity.	2.37612e-178
NC_022997.1|WP_041319081.1|3334051_3335335_-|NADH-quinone-oxidoreductase-subunit-NuoF	gnl|CDD|237441	PRK13596, PRK13596, NADH-quinone oxidoreductase subunit NuoF.	0
NC_022997.1|WP_023788499.1|3330853_3331921_-|NADH-quinone-oxidoreductase-subunit-NuoH	gnl|CDD|235692	PRK06076, PRK06076, NADH-quinone oxidoreductase subunit NuoH.	3.14377e-151
NC_022997.1|WP_023788498.1|3330350_3330839_-|NADH-quinone-oxidoreductase-subunit-NuoI	gnl|CDD|235637	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI.	3.02131e-92
NC_022997.1|WP_051388878.1|3325721_3327275_-|NADH-quinone-oxidoreductase-subunit-M	gnl|CDD|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	0
NC_022997.1|WP_023788506.1|3339638_3339959_+|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	5.18769e-40
NC_022997.1|WP_023788502.1|3335345_3336050_-|NADH-quinone-oxidoreductase-subunit-NuoE	gnl|CDD|237082	PRK12373, PRK12373, NADH-quinone oxidoreductase subunit E.	8.62126e-112
NC_022997.1|WP_081717766.1|3346213_3347608_-|glutamate--cysteine-ligase	gnl|CDD|178221	PLN02611, PLN02611, glutamate--cysteine ligase.	0
NC_022997.1|WP_023788500.1|3331940_3334055_-|NADH-quinone-oxidoreductase-subunit-G	gnl|CDD|236387	PRK09130, PRK09130, NADH dehydrogenase subunit G; Validated.	0
NC_022997.1|WP_158412876.1|3345003_3345729_+|hypothetical-protein	gnl|CDD|366292	pfam00765, Autoind_synth, Autoinducer synthase.	9.7055e-05
NC_022997.1|WP_023788507.1|3340140_3341355_+|saccharopine-dehydrogenase-family-protein	gnl|CDD|224662	COG1748, LYS9, Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism].	1.14261e-146
NC_022997.1|WP_023788496.1|3329239_3329548_-|NADH-quinone-oxidoreductase-subunit-NuoK	gnl|CDD|180218	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK.	4.07207e-42

Protein sequences

>NC_022997.1|WP_023788503.1|3336265_3336613_-|hypothetical-protein
MFDNLFLLAVAALGWGLSLATYSYFAHRHGWPMGALQIDFPAVPVLFGLASAGIAVWFATSRGLDDGGGWVIVLFGVLLAVFWTGFLRVGSQISLFLAPIAAVLLVSGWLSAPLT
>NC_022997.1|WP_023788502.1|3335345_3336050_-|NADH-quinone-oxidoreductase-subunit-NuoE
MAVRRLHPDQPHDFAFTPENMAWATETIAKYPEDKQASAIIPLLWRAQEQSNGWLPEPALRYVADMLGVAYIRAYEVATFYTMFQLSPVGSKAHIQVCGTTPCMLRGAEALVEVCKRRISEEPHGLSEDGSLSWEEVECLGCCANAPMVQVWKDTYEDLAPEALEKLISAFERGSKPQPGSQAGRVSSSPEGPPTTLVDPTLYDGSAIGSWRDRFPELAEGGSAASGQSDKSKG
>NC_022997.1|WP_041319081.1|3334051_3335335_-|NADH-quinone-oxidoreductase-subunit-NuoF
MLEDKDRIFRNLYGVHDSGLDGARKRGAWDGTKFFIDKGHDWIISEVKTSGLRGRGGAGFPTGLKWSFMPKADPRPSYLVINADESEPGSCKDREIMRHDPHLLIEGALLAGFAMRAHTSYIYIRGEFIRERERLQRAIDEAYAAKLIGKNNVHGWDFDLYIAHGAGAYICGEETALLESLEGRKGQPRLKPPFPANVGLYGAPTTVNNVESIAVVGDILRRGGHWFASLGLPNNTGTKLFQISGHVNRPCVVEEEMGIPLRQLIDEHCGGVRGGWNNLLAVIPGGSSMPLIPAEECETLSMDFDSLTKLKSGLGTAAIIVLDKSADVVKAIARIAYFYKHESCGQCTPCREGTGWMWRVLERMARGEAQKSEIDKLFDVSKQIEGHTICALGDAAAWPVQGLIRHFRPEIERRIDAYQAAHREAAE
>NC_022997.1|WP_023788500.1|3331940_3334055_-|NADH-quinone-oxidoreductase-subunit-G
MTRQLIIDGKLIEAEDGLTLLQACEQAGAEIPRFCYHERLSIAGNCRMCLVEVQGSPKPIASCAMGVADLPPNRDNSPKVISTRSETVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAIAYGSGGSRFVENKRAVEEKYIGPLIKTAMTRCIHCTRCVRFMTEVAGVEELGAIGRGEDMEITTYLERGILSEMSANVNDLCPVGALTHRPWAHNARPWELRKTETFDVMDAVGSAIRVDARGREVMRILPRNNDAVNEEWISDKTRHVADGLRTQRLDQPYIRKDGRLVPASWDEALAAVAAKLKAANPDRIAAVAGPLAGAEEMFALKDLFARLGATNVDCREDGVRLDPALGRASYVFNSTIEGIENADAILLIGTNPRLEAAVLNARIRKRWRKGGLTVGLVGERVDLTYAYEHLGSGGRTLAELADGKHAFADVLKNAAAPLVIVGTSALAREDGRAVLAAAARIASAATAGKDADWNGFNVLHTAASRVAGLDLGFVPEKPASTNVESFVAAAGKGELSVLFLLGADDIDTNALGSAFVVYQGSHGDAGAHRADVIFPGAAYTEKSATYVNTEGRAQVTARAVFPPGLAREDWTIVRALSALTGHTLPYDTLEALRAAMYKAAPALAALDRVAHAPADALAALAGDKAAIKDEPFRTAVRDFYLTNPIARASAVMAEMSALTKQAGRPASLAAAE
>NC_022997.1|WP_023788499.1|3330853_3331921_-|NADH-quinone-oxidoreductase-subunit-NuoH
MSDETISTFLDYALWLAIAVGLSLLVIVGLLVCIAFLLLMDRKVWAAVQMRKGPNVVGPFGLFQSFADLLKFVFKEPVIPAGADKGVFLLAPVVMSLCALAAWAVIPMNQNSWGTWVIADLNVGVLYILAISSLGVYGVIMGGWASNSKYPFMSSLRSAAQMISYEVSLGFVVITVLLLVGSLNLAAIVTAQNTGLGTWVGLPASALDWHWLPLLPMFVMFFISALAETNRPPFDLVEAESELVAGFMVEYSSTPYLLFMLGEYVAIVTMCALATILFLGGWLPPLDIWPLNLVPGIFWFGIKVVFMFFMFAMVKAMVPRYRYDQLMRLGWKVFLPLSLAMVVAVAGVLEILRSA
>NC_022997.1|WP_023788498.1|3330350_3330839_-|NADH-quinone-oxidoreductase-subunit-NuoI
MRVAQGLKSLFLAEFVSAFFLAMRYFFAPKKTLNYPFEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIEAGPRRNDGTRRTTRYDIDMVKCIYCGLCQEACPVDAIVEGPNFEFATETREELYYDKERLLANGDRWEREIARNLALDAPYR
>NC_022997.1|WP_023788497.1|3329579_3330212_-|NADH-quinone-oxidoreductase-subunit-J
MALTAIFFYLFATLALASAAMVIVARNPVHAVLFLILTFFNAAGLFILLGAEFLAMLLVIVYVGAVAVLFLFVVMMLDVDFAELRAGFIKNAPVGLLVGGVVLAELVLLVLARGVAHAPAGKGAVPITGAVTNTEALGQVLYTKYVYFFQGAGLVLLVAMIGAIVLTLRHKEGVKRQSVPDQNARSPKTAVEMVKVAPGGSAIPEATAKR
>NC_022997.1|WP_023788496.1|3329239_3329548_-|NADH-quinone-oxidoreductase-subunit-NuoK
MEIGLGHYLTLAACLFTLGMFGIFLNRKNVIVILMSVELMLLAVNINFVAFSHFNADLVGQVFALFVLTVAAAEAAIGLAIIVVYFRNRGSISVDDVSMMKG
>NC_022997.1|WP_041319075.1|3327287_3329228_-|NADH-quinone-oxidoreductase-subunit-L
MYTLIVLLPLAGALIAGLFGRILGPRPSEIVTTALLMIAALLSWVVFVQVGFSGETARVPLFRWITSGDLDTAWSLRIDTLTAVMLVVVTTVSALVHLYSIGYMHEDDSRPRFFAYLSLFTFAMLALVTSDNLVQMFFGWEGVGLASYLLIGFWYKKPSANAAAIKAFVVNRVGDFGFALGIFALFAVFGTISFDAIFAAAPGEVGNTIEFVGYRVDTLTLIALLLFMGAMGKSAQFLLHTWLPDAMEGPTPVSALIHAATMVTAGVFMVARLSPVFELAPAALNVVVFIGALTAFFAATVGLVQNDIKRVIAYSTCSQLGYMFVALGVGAYSAGIFHLFTHAFFKALLFLGAGSVIHGLHHEQDMRRMGGLSKKLPFTWAMMLIGTLALTGVGIPHLVGFAGFHSKDAIIEAAYAAHTPSNYAFWALIVAAFMTSFYSWRLMFLTFHGETRADHHAYDEAHEGPWVMRIPLIVLSVGAVFAGVVFYPYFMGSGYEGFWREALYELPGKDIRHHMHEVPEWVFWAPAIAMLAGLGLATLYYIVKPGLPEATARAFRPVYLFLLNKWYIDELYDRIFVRPAFAIGRFLWKGIDGAVIDGAIDRVTRGVLWGTGFVNRFQTGYLYHYAFAMLIGVAGLLTYFILTGGR
>NC_022997.1|WP_051388878.1|3325721_3327275_-|NADH-quinone-oxidoreductase-subunit-M
MSAAPILSIVTFLPLVGALFIALLSREAVQNIRYTALWTTLITFALSLLIWINFDASSAGFQFVEERDWLGPIKYKMGVDGISMLFVILTTFLMPLCILASWESIGKRVKEYMIAFLVLETLVIGVFCALDLVLFYVFFEGGLIPMFLIIGVWGGARRVYASFKFFLYTFLGSVLMLVAMMAMYWHAGTTDIPTLLTTTFPSDMQFWLWLAFFASFAVKMPMWPVHTWLPDAHVEAPTAGSVILAGILLKLGGYGFLRFSLPMFPEASETFAPLVFGLSVIAIVATSLIALVQEDMKKLIAYSSVAHMGFVTMGIFTFSRQGIDGAIFQMLSHGLISSALFLCVGVVYDRLHTREIKAYGGIVERMPIYAAIFLVFTMGNVGLPGTSGFVGEFLTLLAAFKANTLVAVIATSGVIFSAAYALYLYRQVVFGPLEKPSLKALADVTPREIAILAPLLLLTIFFGFYPAPILDVTGASVEALAQQIAGATGTAVDAAAGAASEAAGEVAPASPPAEPTP
>NC_022997.1|WP_023788504.1|3337065_3338913_+|DNA-polymerase-III-subunit-gamma/tau
MAKKKSEDTSQVEGSAAAAKPYVVLARKYRPQTFDDLIGQETMVQTLRNAFAAGRIAHGFMLTGVRGVGKTTTARILARALNYETDTVDKPTIDMPSPGRHCIEIMESRHPDVIEMDAASNTGVDNIREIIESARYRPLAARTKVFIIDEVHMLSKGAFNALLKTLEEPPGHVKFIFATTEVRKVPVTVLSRCQRFDLRRVDVPRLVQHLKNIVANEGAAADDDALTLIARAAEGSVRDALSMLDQAIATALGPTPGDASTVSADAVRGLLGLADRGRVFDLLETLAAGDIATALKSLDGLIHDGADAAQVLADLSEAVHITARIKAVGPDAAGEGLALAEKQRAGALGGQLSMGFLSRLWQMLLKGLEEAGKAPNPVAAAQMVLIRIAHTADLPPPDEVIRALGGAPDVRRSGAPAPSQAAPAPVATRTNAPVASYDDEPNDDRFTFEGLESGEGPEPESFEGFETADDDGGEDLSTVPGVPLRPLNTFTDIVALARDKRDAKLTLALEEEVSLVRFDGATGAIDLYLLPGAPAGLANDLREKLNKWTGRRWVTMLSKTPGERPLGEVRREREALEREALRNHPAVAAVLEAFPDAEITVWPLDSIPDDDSATG
>NC_022997.1|WP_023788505.1|3339101_3339356_+|hypothetical-protein
MRSLALSAVALAFVSGAAFAASEGKFSQATVNGITKSLEADGCKLGEIHSGDGFYTIAGSTCADGTYDVTVDTDFKITDKKKKD
>NC_022997.1|WP_023788506.1|3339638_3339959_+|YbaB/EbfC-family-nucleoid-associated-protein
MKDLMGMMKQVKDMQERMQRLQDELASMEVTGAAGGGLVSVTLNGKGDFQRVKIDPSLMKPEEAEIVEDLIIAAAADAKAKVEATLQEKMSEMTGGLPLPPGLKLF
>NC_022997.1|WP_023788507.1|3340140_3341355_+|saccharopine-dehydrogenase-family-protein
MDSVLIIGAGAAGSVTAQKCAMNRDVFKKVHLASRRLESCEKVAARCVSPIEISQVDADNVDETVALIERVKPDLVINMALPYQDLPIMDACLKTGVHYMDTANYEPRDVAKFEYSWQWAYHDRYAERGILGVLGCGFDPGVSNIFCAYAQEHLFDTIETIDIIDCNDGSHGKSFATNFNPEINLREVTQRGKYWKNGEWIDIDPLSISTMIDYPEVGPRKSYLIYHEEEESLVRNIKGLKQIRFWMTFSENYIKHLDVLQSVGMTRIDPVMYKGTPVIPMEFLKELLPPPSSLGENYTGRTSIGCVIDGTKDGKRKTVLIYNVCDHAESYKETGAQAVSYTTGVPPVVGAIQMFQGAWTGNGVLNVEQLPSKPFLDELAKQGLPWHVKEITPDDQAELFAVKS
>NC_022997.1|WP_051388882.1|3341558_3342836_+|hypothetical-protein
MVTVHGTNDAALDDTGERWWQTGSTFTNRLAERLAARGIPQPEIVPVHWSGKNSDHDRLKGAEALARTLRGLHREGRQHAVLAHSHGGNVAVEGLARARPSAQRGAIISFGTPFFVRKLKTVPRLIALFQLVLGLVIPPIMLWYLIEVLPGDSNKKIEAVVLFSGLFALGVWSLIAGVRKLARRHLAERRFARSLSPSQWLVVHSPRDEAMQLLETAAEINPEYVTTASAMRSLTAFASLAGVIATVAFFVWTGSYFLTPILEKVREGTYGLALGADLTFLLLVPVIYGAVFFAIWLAARAGGAWAYAKFLTSAIHGGVVGAAFGGDDAFKLVGVTRLPPYLVQGREERIEAIDLGGIDDAALFVAAQSLYNSVVANDGPDGGIANPDAMWKRLSDALYHNAYMRDDNVIETVAEHIAATWRQTA
>NC_022997.1|WP_023788509.1|3343013_3343415_+|hypothetical-protein
MAHLSEKLAEMHRRIAEDAQEEQALVRALNAALNHVDEKLLAEIRHVTVQHEARRSAIMNELQLLATRLCAFPAPPAERRPALEGGYADGGHLNGEHLNGHTHAPGNWRIAAQNVEDDDLDFFTDGPAAPASH
>NC_022997.1|WP_023788511.1|3343713_3344862_+|carboxynorspermidine-decarboxylase
MLPKLPDDIRTPAYVLDVAALKRNLETAARIKREAGVKILLATKAWAMPAAFPLLDDTLAGTTASGEYEARLGREEFGREVHVYAPAYGPGEIERLIDIADHIYANSPDEMARVLKAVRESGRTNIHVGARINPGYSNATLGGALYDPCAPNSRFGTTAEEIDRLPWDDIDIFHAHALCESLADGSVGLIDHVARTFEPYLRRVKAVNFGGGHFINKPGYDVGKLIAALKAFRAEFGIEVYLEPGAGLVVDAGYLVSSVIGIHRNVGEIAILDASASTHMPDVLEVPYTPTIIGADKPGVHPFTYILGGKTCMTGDVIGEYSFDAPLKPGDRLVFTDMMQYSFVKNTTFNGTPLPDLAILHEDGRYEVVRSFGYEEFRRRLG
>NC_022997.1|WP_158412876.1|3345003_3345729_+|hypothetical-protein
MGASMMFQPPLVLDNNNGDTAKNFPISLEIYSSHSDKTDLHRLRYRAFLAAGWIRENDAGMLSDRFDALDTTVAVGAFHKGACIGALRLAFGGAHALPHSMPCEDAFPDEVRALIAQNCQRLVEFSRMAVEPTLSNRSFRTTLYASLVRAGVMLTIASRVDMAVVAVHKKVSPFYQAMCGFEVLGKSASYAEIDEPTEFLGLRAQALEARRKKRSGFFAFSPEEIAAAERALARLSAQGLA
>NC_022997.1|WP_144083628.1|3345840_3346044_-|hypothetical-protein
MSRIVRYAILLACLGTLPAVAVSTVAGANQCAAKCYAEENACRRATKDSPSCGAALTRCLQSCRAQR
>NC_022997.1|WP_081717766.1|3346213_3347608_-|glutamate--cysteine-ligase
MSTRQDGAQDGAKRPRVRSETDLVAWIAAGEKPKADWRIGTEHEKFVFHTDTLTPVPYEGERGIRALMEQLMARYDWEPIKEGENIIALKRPDAAPGGTISLEPGGQFELSGAPLRSLHETCAETQEHLFEVLSVGEDLGIGFLGVGFSPKWTLDETPRMPKARYQVMTRYMPEVGRRGLDMMYRTTTIQVNLDFATEADMVKKLRVSLALQPIATAIFASSPFTEGRPNGFKSLRSEVWRETDKRRTGMLPFVFEDGMGYARYVDYALDVPMYFVYRDGRYIDVAGASFRDFLAGKLAAMPGEYPTLDDWSDHLTTLFPEVRLKRFLEMRGADGGRWRRICALPAFWVGLLYDETSLDAAWDLVKSWTEEEREALRNAVPREALATRFRETTVQELAREVLRISHAGLRRRQQLNRKSQDETIFLSPLEAAVASGRTVADELLERFHGPWNGRIDHVFAEFAF

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_022997_8	8.1|2622341|60|NC_022997|CRISPRCasFinder	2622341-2622400	60	NC_022997.1	2381547-2381606	0	1.0
NC_022997_3	3.1|677285|35|NC_022997|CRISPRCasFinder	677285-677319	35	NC_022997.1	2005169-2005203	1	0.971
NC_022997_3	3.1|677285|35|NC_022997|CRISPRCasFinder	677285-677319	35	NC_022997.1	2670937-2670971	1	0.971
NC_022997_6	6.1|1473195|25|NC_022997|CRISPRCasFinder	1473195-1473219	25	NC_022997.1	2414452-2414476	1	0.96
NC_022997_10	10.1|2855636|35|NC_022997|CRISPRCasFinder	2855636-2855670	35	NC_022997.1	920723-920757	1	0.971
NC_022997_10	10.1|2855636|35|NC_022997|CRISPRCasFinder	2855636-2855670	35	NC_022997.1	2709506-2709540	1	0.971
NC_022997_10	10.1|2855636|35|NC_022997|CRISPRCasFinder	2855636-2855670	35	NC_022997.1	3386043-3386077	1	0.971
NC_022997_2	2.1|406092|32|NC_022997|CRISPRCasFinder	406092-406123	32	NC_022997.1	529846-529877	2	0.938
NC_022997_6	6.1|1473195|25|NC_022997|CRISPRCasFinder	1473195-1473219	25	NC_022997.1	595157-595181	2	0.92
NC_022997_8	8.1|2622341|60|NC_022997|CRISPRCasFinder	2622341-2622400	60	NC_022997.1	3476055-3476114	2	0.967
NC_022997_10	10.1|2855636|35|NC_022997|CRISPRCasFinder	2855636-2855670	35	NC_022997.1	2709447-2709481	2	0.943

1. spacer 8.1|2622341|60|NC_022997|CRISPRCasFinder matches to position: 2381547-2381606, mismatch: 0, identity: 1.0

ccagacgggcaaaagagccgcgcggctccgccgtgagacaagattgatcgatggcggcgt	CRISPR spacer
ccagacgggcaaaagagccgcgcggctccgccgtgagacaagattgatcgatggcggcgt	Protospacer
************************************************************

2. spacer 3.1|677285|35|NC_022997|CRISPRCasFinder matches to position: 2005169-2005203, mismatch: 1, identity: 0.971

cttgagttagaccgatgattcacgcttcaggctgg	CRISPR spacer
cttgagctagaccgatgattcacgcttcaggctgg	Protospacer
******.****************************

3. spacer 3.1|677285|35|NC_022997|CRISPRCasFinder matches to position: 2670937-2670971, mismatch: 1, identity: 0.971

cttgagttagaccgatgattcacgcttcaggctgg	CRISPR spacer
cttgggttagaccgatgattcacgcttcaggctgg	Protospacer
****.******************************

4. spacer 6.1|1473195|25|NC_022997|CRISPRCasFinder matches to position: 2414452-2414476, mismatch: 1, identity: 0.96

cttgagttagaccgatgattcacgt	CRISPR spacer
cttgagtgagaccgatgattcacgt	Protospacer
******* *****************

5. spacer 10.1|2855636|35|NC_022997|CRISPRCasFinder matches to position: 920723-920757, mismatch: 1, identity: 0.971

cttgagttagacctatgattcacgcttcggactga	CRISPR spacer
cttgagttagaccgatgattcacgcttcggactga	Protospacer
************* *********************

6. spacer 10.1|2855636|35|NC_022997|CRISPRCasFinder matches to position: 2709506-2709540, mismatch: 1, identity: 0.971

cttgagttagacctatgattcacgcttcggactga	CRISPR spacer
cttgagttagaccgatgattcacgcttcggactga	Protospacer
************* *********************

7. spacer 10.1|2855636|35|NC_022997|CRISPRCasFinder matches to position: 3386043-3386077, mismatch: 1, identity: 0.971

cttgagttagacctatgattcacgcttcggactga	CRISPR spacer
cttgagttagaccgatgattcacgcttcggactga	Protospacer
************* *********************

8. spacer 2.1|406092|32|NC_022997|CRISPRCasFinder matches to position: 529846-529877, mismatch: 2, identity: 0.938

aggctggcagggtctgaagcgatcatggtctt	CRISPR spacer
aggctggtagggcctgaagcgatcatggtctt	Protospacer
*******.****.*******************

9. spacer 6.1|1473195|25|NC_022997|CRISPRCasFinder matches to position: 595157-595181, mismatch: 2, identity: 0.92

cttgagttagaccgatgattcacgt	CRISPR spacer
ctttcgttagaccgatgattcacgt	Protospacer
***  ********************

10. spacer 8.1|2622341|60|NC_022997|CRISPRCasFinder matches to position: 3476055-3476114, mismatch: 2, identity: 0.967

ccagacgggcaaaagagccgcgcggctccgccgtgagacaagattgatcgatggcggcgt	CRISPR spacer
ccagacgggcaaaagagccgcgcggctccgccgtgagacaagattggccgatggcggcgt	Protospacer
**********************************************..************

11. spacer 10.1|2855636|35|NC_022997|CRISPRCasFinder matches to position: 2709447-2709481, mismatch: 2, identity: 0.943

cttgagttagacctatgattcacgcttcggactga	CRISPR spacer
cttgagctagaccgatgattcacgcttcggactga	Protospacer
******.****** *********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_022997_5	5.3|1447458|23|NC_022997|CRISPRCasFinder,CRT	1447458-1447480	23	MT708550	Achromobacter phage Mano, complete genome	28063-28085	1	0.957
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN693749	Marine virus AFVG_250M1175, complete genome	38040-38073	6	0.824
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN694794	Marine virus AFVG_250M1172, complete genome	38745-38778	6	0.824
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN694703	Marine virus AFVG_250M1171, complete genome	38658-38691	6	0.824
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN694422	Marine virus AFVG_250M844, complete genome	36533-36566	6	0.824
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN693830	Marine virus AFVG_250M842, complete genome	36080-36113	6	0.824
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN694319	Marine virus AFVG_250M843, complete genome	36199-36232	6	0.824
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN693767	Marine virus AFVG_250M1169, complete genome	38853-38886	6	0.824
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN693633	Marine virus AFVG_250M1174, complete genome	1671-1704	6	0.824
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN693832	Marine virus AFVG_250M1173, complete genome	1671-1704	6	0.824
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN694684	Marine virus AFVG_250M1170, complete genome	1669-1702	6	0.824
NC_022997_5	5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT	1449153-1449186	34	MN694707	Marine virus AFVG_250M1176, complete genome	1671-1704	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN693749	Marine virus AFVG_250M1175, complete genome	38040-38073	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN694794	Marine virus AFVG_250M1172, complete genome	38745-38778	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN694703	Marine virus AFVG_250M1171, complete genome	38658-38691	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN694422	Marine virus AFVG_250M844, complete genome	36533-36566	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN693830	Marine virus AFVG_250M842, complete genome	36080-36113	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN694319	Marine virus AFVG_250M843, complete genome	36199-36232	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN693767	Marine virus AFVG_250M1169, complete genome	38853-38886	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN693633	Marine virus AFVG_250M1174, complete genome	1671-1704	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN693832	Marine virus AFVG_250M1173, complete genome	1671-1704	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN694684	Marine virus AFVG_250M1170, complete genome	1669-1702	6	0.824
NC_022997_5	5.51|1449161|34|NC_022997|PILER-CR	1449161-1449194	34	MN694707	Marine virus AFVG_250M1176, complete genome	1671-1704	6	0.824
NC_022997_11	11.1|3336984|28|NC_022997|CRISPRCasFinder	3336984-3337011	28	NZ_CP051182	Thalassobius gelatinovorus strain NEB572 plasmid pAge77, complete sequence	50557-50584	6	0.786
NC_022997_11	11.1|3336984|28|NC_022997|CRISPRCasFinder	3336984-3337011	28	NZ_CP025614	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed2, complete sequence	227088-227115	6	0.786
NC_022997_11	11.1|3336984|28|NC_022997|CRISPRCasFinder	3336984-3337011	28	NC_020548	Azoarcus sp. KH32C plasmid pAZKH, complete sequence	268082-268109	6	0.786
NC_022997_2	2.1|406092|32|NC_022997|CRISPRCasFinder	406092-406123	32	NZ_CP026318	Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence	73900-73931	7	0.781
NC_022997_5	5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT	1447647-1447678	32	NZ_CP021373	Rhizobium sp. ACO-34A plasmid pRACO34Ac, complete sequence	391833-391864	7	0.781
NC_022997_5	5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT	1447647-1447678	32	MK415402	Phage apr34_1792, complete genome	18536-18567	7	0.781
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NZ_CP024312	Rhizobium sp. NXC24 plasmid pRspNXC24a, complete sequence	4380-4413	7	0.794
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NZ_CP024940	Paraburkholderia hospita strain mHSR1 plasmid pmHSR1_P, complete sequence	1153943-1153976	7	0.794
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	557903-557936	7	0.794
NC_022997_5	5.10|1447926|30|NC_022997|CRISPRCasFinder,CRT	1447926-1447955	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2697783-2697812	7	0.767
NC_022997_5	5.10|1447926|30|NC_022997|CRISPRCasFinder,CRT	1447926-1447955	30	NZ_LR134467	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence	22887-22916	7	0.767
NC_022997_5	5.37|1447648|31|NC_022997|PILER-CR	1447648-1447678	31	NZ_CP021373	Rhizobium sp. ACO-34A plasmid pRACO34Ac, complete sequence	391834-391864	7	0.774
NC_022997_2	2.1|406092|32|NC_022997|CRISPRCasFinder	406092-406123	32	NC_009472	Acidiphilium cryptum JF-5 plasmid pACRY06, complete sequence	6401-6432	8	0.75
NC_022997_5	5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT	1447647-1447678	32	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	104140-104171	8	0.75
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	MF975721	Pseudomonas phage VW-6B, complete genome	24864-24897	8	0.765
NC_022997_5	5.10|1447926|30|NC_022997|CRISPRCasFinder,CRT	1447926-1447955	30	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	646114-646143	8	0.733
NC_022997_5	5.10|1447926|30|NC_022997|CRISPRCasFinder,CRT	1447926-1447955	30	NZ_CP042998	Aquisphaera giovannonii strain OJF2 plasmid pOJF2_1, complete sequence	27435-27464	8	0.733
NC_022997_5	5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448230-1448263	34	NC_016588	Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence	142135-142168	8	0.765
NC_022997_5	5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448230-1448263	34	NZ_CP014276	Martelella sp. AD-3 plasmid unnamed1, complete sequence	303841-303874	8	0.765
NC_022997_5	5.23|1448824|34|NC_022997|CRISPRCasFinder,CRT	1448824-1448857	34	NZ_CP045223	Achromobacter xylosoxidans strain DN002 plasmid unnamed	237368-237401	8	0.765
NC_022997_5	5.33|1449484|34|NC_022997|CRISPRCasFinder,CRT	1449484-1449517	34	NC_018696	Paraburkholderia phenoliruptrix BR3459a plasmid pSYMBR3459, complete sequence	47387-47420	8	0.765
NC_022997_5	5.37|1447648|31|NC_022997|PILER-CR	1447648-1447678	31	NZ_CP035419	Leisingera sp. NJS204 plasmid unnamed2, complete sequence	75691-75721	8	0.742
NC_022997_5	5.37|1447648|31|NC_022997|PILER-CR	1447648-1447678	31	NZ_CP038239	Leisingera sp. NJS201 plasmid unnamed5, complete sequence	15555-15585	8	0.742
NC_022997_5	5.37|1447648|31|NC_022997|PILER-CR	1447648-1447678	31	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	104141-104171	8	0.742
NC_022997_5	5.37|1447648|31|NC_022997|PILER-CR	1447648-1447678	31	MT711977	Streptomyces phage Dagobah, complete genome	38868-38898	8	0.742
NC_022997_5	5.46|1448832|34|NC_022997|PILER-CR	1448832-1448865	34	NZ_CP045223	Achromobacter xylosoxidans strain DN002 plasmid unnamed	237368-237401	8	0.765
NC_022997_5	5.56|1449492|34|NC_022997|PILER-CR	1449492-1449525	34	NC_018696	Paraburkholderia phenoliruptrix BR3459a plasmid pSYMBR3459, complete sequence	47387-47420	8	0.765
NC_022997_7	7.2|2508872|31|NC_022997|CRISPRCasFinder	2508872-2508902	31	NZ_CP039918	Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626a, complete sequence	159355-159385	8	0.742
NC_022997_9	9.1|2786478|32|NC_022997|CRISPRCasFinder	2786478-2786509	32	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	953899-953930	8	0.75
NC_022997_5	5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT	1447647-1447678	32	NZ_CP035419	Leisingera sp. NJS204 plasmid unnamed2, complete sequence	75690-75721	9	0.719
NC_022997_5	5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT	1447647-1447678	32	NZ_CP038239	Leisingera sp. NJS201 plasmid unnamed5, complete sequence	15555-15586	9	0.719
NC_022997_5	5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT	1447647-1447678	32	MT711977	Streptomyces phage Dagobah, complete genome	38868-38899	9	0.719
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	502713-502746	9	0.735
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	492289-492322	9	0.735
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	457619-457652	9	0.735
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	216647-216680	9	0.735
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	502751-502784	9	0.735
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	502750-502783	9	0.735
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	502742-502775	9	0.735
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NZ_AP014686	Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6b, complete sequence	179973-180006	9	0.735
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	AP014720	Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8	33071-33104	9	0.735
NC_022997_5	5.12|1448053|34|NC_022997|CRISPRCasFinder,CRT	1448053-1448086	34	AP014020	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C109A-MedDCM-OCT-S27-C18, *** SEQUENCING IN PROGRESS ***	34550-34583	9	0.735
NC_022997_5	5.12|1448053|34|NC_022997|CRISPRCasFinder,CRT	1448053-1448086	34	AP014021	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C109A-MedDCM-OCT-S44-C26, *** SEQUENCING IN PROGRESS ***	32389-32422	9	0.735
NC_022997_5	5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448230-1448263	34	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	695481-695514	9	0.735
NC_022997_5	5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448230-1448263	34	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	683306-683339	9	0.735
NC_022997_5	5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448230-1448263	34	NZ_CP039651	Azospirillum sp. TSA2s plasmid p1	26244-26277	9	0.735
NC_022997_5	5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448230-1448263	34	NC_013860	Azospirillum sp. B510 plasmid pAB510f, complete sequence	191563-191596	9	0.735
NC_022997_5	5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448230-1448263	34	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	476856-476889	9	0.735
NC_022997_5	5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448296-1448329	34	NZ_CP053236	Escherichia coli strain SCU-106 plasmid pSCU-106-2, complete sequence	23510-23543	9	0.735
NC_022997_5	5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448296-1448329	34	NZ_CP023734	Escherichia coli strain FORC 064 plasmid pFORC64.3, complete sequence	36318-36351	9	0.735
NC_022997_5	5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448296-1448329	34	NZ_CP047380	Escherichia coli strain CAU16175 plasmid pCAU16175_2, complete sequence	83502-83535	9	0.735
NC_022997_5	5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448296-1448329	34	NZ_CP024975	Escherichia coli strain CV839-15 plasmid pCV839-15-p1, complete sequence	70471-70504	9	0.735
NC_022997_5	5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448296-1448329	34	NZ_CP025752	Escherichia coli strain CV839-06 plasmid pCV839-06-p2, complete sequence	8305-8338	9	0.735
NC_022997_5	5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448296-1448329	34	NZ_MG904994	Escherichia coli strain 14OD0056 plasmid p14ODV, complete sequence	44933-44966	9	0.735
NC_022997_5	5.22|1448758|34|NC_022997|CRISPRCasFinder,CRT	1448758-1448791	34	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	1388434-1388467	9	0.735
NC_022997_5	5.25|1448955|34|NC_022997|CRISPRCasFinder,CRT	1448955-1448988	34	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	238289-238322	9	0.735
NC_022997_5	5.26|1449021|34|NC_022997|CRISPRCasFinder,CRT	1449021-1449054	34	NZ_AP018921	Pseudonocardia autotrophica strain NBRC 12743 plasmid pPA12743CP, complete sequence	12960-12993	9	0.735
NC_022997_5	5.26|1449021|34|NC_022997|CRISPRCasFinder,CRT	1449021-1449054	34	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	747269-747302	9	0.735
NC_022997_5	5.45|1448766|34|NC_022997|PILER-CR	1448766-1448799	34	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	1388434-1388467	9	0.735
NC_022997_5	5.48|1448963|34|NC_022997|PILER-CR	1448963-1448996	34	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	238289-238322	9	0.735
NC_022997_5	5.49|1449029|34|NC_022997|PILER-CR	1449029-1449062	34	NZ_AP018921	Pseudonocardia autotrophica strain NBRC 12743 plasmid pPA12743CP, complete sequence	12960-12993	9	0.735
NC_022997_5	5.49|1449029|34|NC_022997|PILER-CR	1449029-1449062	34	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	747269-747302	9	0.735
NC_022997_5	5.1|1447325|34|NC_022997|CRISPRCasFinder,CRT	1447325-1447358	34	NZ_CP017600	Moorea producens PAL-8-15-08-1 plasmid unnamed, complete sequence	21657-21690	10	0.706
NC_022997_5	5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR	1447860-1447893	34	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	346875-346908	10	0.706
NC_022997_5	5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448230-1448263	34	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4892754-4892787	10	0.706
NC_022997_5	5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT	1448230-1448263	34	NZ_CP034087	Methylocystis rosea strain GW6 plasmid pGW6_1, complete sequence	175533-175566	10	0.706
NC_022997_5	5.24|1448890|33|NC_022997|CRISPRCasFinder,CRT	1448890-1448922	33	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	981827-981859	10	0.697
NC_022997_5	5.24|1448890|33|NC_022997|CRISPRCasFinder,CRT	1448890-1448922	33	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1798509-1798541	10	0.697
NC_022997_5	5.24|1448890|33|NC_022997|CRISPRCasFinder,CRT	1448890-1448922	33	NZ_CP030127	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence	942016-942048	10	0.697
NC_022997_5	5.24|1448890|33|NC_022997|CRISPRCasFinder,CRT	1448890-1448922	33	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1644867-1644899	10	0.697
NC_022997_5	5.25|1448955|34|NC_022997|CRISPRCasFinder,CRT	1448955-1448988	34	NZ_CP019319	Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-7, complete sequence	15287-15320	10	0.706
NC_022997_5	5.26|1449021|34|NC_022997|CRISPRCasFinder,CRT	1449021-1449054	34	NC_022042	Paracoccus aminophilus JCM 7686 plasmid pAMI1, complete sequence	15600-15633	10	0.706
NC_022997_5	5.47|1448898|33|NC_022997|PILER-CR	1448898-1448930	33	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	981827-981859	10	0.697
NC_022997_5	5.47|1448898|33|NC_022997|PILER-CR	1448898-1448930	33	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1798509-1798541	10	0.697
NC_022997_5	5.47|1448898|33|NC_022997|PILER-CR	1448898-1448930	33	NZ_CP030127	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence	942016-942048	10	0.697
NC_022997_5	5.47|1448898|33|NC_022997|PILER-CR	1448898-1448930	33	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1644867-1644899	10	0.697
NC_022997_5	5.48|1448963|34|NC_022997|PILER-CR	1448963-1448996	34	NZ_CP019319	Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-7, complete sequence	15287-15320	10	0.706
NC_022997_5	5.49|1449029|34|NC_022997|PILER-CR	1449029-1449062	34	NC_022042	Paracoccus aminophilus JCM 7686 plasmid pAMI1, complete sequence	15600-15633	10	0.706
NC_022997_7	7.2|2508872|31|NC_022997|CRISPRCasFinder	2508872-2508902	31	NZ_CP039918	Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626a, complete sequence	159234-159264	10	0.677
NC_022997_9	9.1|2786478|32|NC_022997|CRISPRCasFinder	2786478-2786509	32	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	227847-227878	10	0.688

1. spacer 5.3|1447458|23|NC_022997|CRISPRCasFinder,CRT matches to MT708550 (Achromobacter phage Mano, complete genome) position: , mismatch: 1, identity: 0.957

catggcgttgcggacaggccgat	CRISPR spacer
catggcgtggcggacaggccgat	Protospacer
******** **************

2. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN693749 (Marine virus AFVG_250M1175, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

3. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN694794 (Marine virus AFVG_250M1172, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

4. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN694703 (Marine virus AFVG_250M1171, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

5. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN694422 (Marine virus AFVG_250M844, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

6. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN693830 (Marine virus AFVG_250M842, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

7. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN694319 (Marine virus AFVG_250M843, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

8. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN693767 (Marine virus AFVG_250M1169, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

9. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN693633 (Marine virus AFVG_250M1174, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

10. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN693832 (Marine virus AFVG_250M1173, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

11. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN694684 (Marine virus AFVG_250M1170, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

12. spacer 5.28|1449153|34|NC_022997|CRISPRCasFinder,CRT matches to MN694707 (Marine virus AFVG_250M1176, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

13. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN693749 (Marine virus AFVG_250M1175, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

14. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN694794 (Marine virus AFVG_250M1172, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

15. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN694703 (Marine virus AFVG_250M1171, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

16. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN694422 (Marine virus AFVG_250M844, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

17. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN693830 (Marine virus AFVG_250M842, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

18. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN694319 (Marine virus AFVG_250M843, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

19. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN693767 (Marine virus AFVG_250M1169, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

20. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN693633 (Marine virus AFVG_250M1174, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

21. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN693832 (Marine virus AFVG_250M1173, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

22. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN694684 (Marine virus AFVG_250M1170, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

23. spacer 5.51|1449161|34|NC_022997|PILER-CR matches to MN694707 (Marine virus AFVG_250M1176, complete genome) position: , mismatch: 6, identity: 0.824

agggcgcctattacgccaagtcgctgacggacgc--	CRISPR spacer
tgggcgcctattacgccaaggcgct--cgaccgcat	Protospacer
 ******************* ****  **. ***  

24. spacer 11.1|3336984|28|NC_022997|CRISPRCasFinder matches to NZ_CP051182 (Thalassobius gelatinovorus strain NEB572 plasmid pAge77, complete sequence) position: , mismatch: 6, identity: 0.786

gctgtttgttcggcggcactggccgcgt	CRISPR spacer
accggctgttcggcggcgctggccgcga	Protospacer
.*.* .***********.********* 

25. spacer 11.1|3336984|28|NC_022997|CRISPRCasFinder matches to NZ_CP025614 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.786

gctgtttgttcggcggcactggccgcgt	CRISPR spacer
gcgccatgatcggcggcactggccgcga	Protospacer
**  . ** ****************** 

26. spacer 11.1|3336984|28|NC_022997|CRISPRCasFinder matches to NC_020548 (Azoarcus sp. KH32C plasmid pAZKH, complete sequence) position: , mismatch: 6, identity: 0.786

gctgtttgttcggcggcactggccgcgt	CRISPR spacer
gcgcgccgttcggcggcacaggccgcgt	Protospacer
**   ..************ ********

27. spacer 2.1|406092|32|NC_022997|CRISPRCasFinder matches to NZ_CP026318 (Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence) position: , mismatch: 7, identity: 0.781

aggctggcagggtctgaagcgatcatggtctt	CRISPR spacer
agatcggcagggtctgcggcgatcatggtatc	Protospacer
**...*********** .*********** *.

28. spacer 5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP021373 (Rhizobium sp. ACO-34A plasmid pRACO34Ac, complete sequence) position: , mismatch: 7, identity: 0.781

tgtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
ttcaggttcggcgagttgaggtcgcagatgaa	Protospacer
* .  **.***** ***************** 

29. spacer 5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT matches to MK415402 (Phage apr34_1792, complete genome) position: , mismatch: 7, identity: 0.781

tgtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
tgtccgtccggcgcgtcaaggtccagggcgat	Protospacer
****************..*****  .*..***

30. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024312 (Rhizobium sp. NXC24 plasmid pRspNXC24a, complete sequence) position: , mismatch: 7, identity: 0.794

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
gagcgccgcaggccgccggcgaagccgatcagca	Protospacer
  ***********.********.******  * *

31. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024940 (Paraburkholderia hospita strain mHSR1 plasmid pmHSR1_P, complete sequence) position: , mismatch: 7, identity: 0.794

ctgcgccgcaggctgccggcgaggccgatgtgga-	CRISPR spacer
ctgcgcggcaggctgccggcgagg-cggcgcaaaa	Protospacer
****** ***************** **..*...* 

32. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 7, identity: 0.794

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
cggcgccgcaggctgcgggcgagcccgtggccga	Protospacer
* ************** ****** ***  *. **

33. spacer 5.10|1447926|30|NC_022997|CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.767

cgggttccacgtcacgctgctcgccacaga	CRISPR spacer
cgggatccacgtcacgctgatcgagcccgg	Protospacer
**** ************** ***   * *.

34. spacer 5.10|1447926|30|NC_022997|CRISPRCasFinder,CRT matches to NZ_LR134467 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence) position: , mismatch: 7, identity: 0.767

cgggttccacgtcacgctgctcgccacaga	CRISPR spacer
ctggttcgacgtcacggtgctcgccctggc	Protospacer
* ***** ******** ******** ..* 

35. spacer 5.37|1447648|31|NC_022997|PILER-CR matches to NZ_CP021373 (Rhizobium sp. ACO-34A plasmid pRACO34Ac, complete sequence) position: , mismatch: 7, identity: 0.774

gtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
tcaggttcggcgagttgaggtcgcagatgaa	Protospacer
 .  **.***** ***************** 

36. spacer 2.1|406092|32|NC_022997|CRISPRCasFinder matches to NC_009472 (Acidiphilium cryptum JF-5 plasmid pACRY06, complete sequence) position: , mismatch: 8, identity: 0.75

aggctggcagggtctgaagcgatcatggtctt	CRISPR spacer
tgtgtatcagggtctgaagcgatcctgctcta	Protospacer
 *  *. ***************** ** *** 

37. spacer 5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tgtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
tgtccgtcgggcgcggtgaggtcgtctgtgtg	Protospacer
******** ****** ********.  .**  

38. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to MF975721 (Pseudomonas phage VW-6B, complete genome) position: , mismatch: 8, identity: 0.765

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
cggcggcgcaggctgccggcaaggccccggaaga	Protospacer
* *** **************.*****   * .**

39. spacer 5.10|1447926|30|NC_022997|CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.733

cgggttccacgtcacgctgctcgccacaga	CRISPR spacer
cccccgccgcgtcacgctgctcgccaccgg	Protospacer
*   . **.****************** *.

40. spacer 5.10|1447926|30|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP042998 (Aquisphaera giovannonii strain OJF2 plasmid pOJF2_1, complete sequence) position: , mismatch: 8, identity: 0.733

cgggttccacgtcacgctgctcgccacaga	CRISPR spacer
caacatccacgtctcgctgctcgccaaggc	Protospacer
*..  ******** ************ .* 

41. spacer 5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NC_016588 (Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence) position: , mismatch: 8, identity: 0.765

agaccgtggggcagatgctcgaagccgtctggga	CRISPR spacer
cggtcgtggcgcagatgctggaagccgtctctgc	Protospacer
 *..***** ********* **********  * 

42. spacer 5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP014276 (Martelella sp. AD-3 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

agaccgtggggcagatgctcgaagccgtctggga	CRISPR spacer
ttaccgaggcgcagatgctcgaagccgtgcgcgc	Protospacer
  **** ** ****************** .* * 

43. spacer 5.23|1448824|34|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP045223 (Achromobacter xylosoxidans strain DN002 plasmid unnamed) position: , mismatch: 8, identity: 0.765

-cagcagctcatgccgcgcggcgcactcgtgcaaa	CRISPR spacer
tccgca-ctcattgcgcgcggcgcactcgtggttg	Protospacer
 * *** *****  *****************   .

44. spacer 5.33|1449484|34|NC_022997|CRISPRCasFinder,CRT matches to NC_018696 (Paraburkholderia phenoliruptrix BR3459a plasmid pSYMBR3459, complete sequence) position: , mismatch: 8, identity: 0.765

ctgtgatcgcggagaagcaggaacaggtgatcgc	CRISPR spacer
acgtgatcgcggcgaagcaggaaaaggtactggt	Protospacer
 .********** ********** ****. * *.

45. spacer 5.37|1447648|31|NC_022997|PILER-CR matches to NZ_CP035419 (Leisingera sp. NJS204 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

gtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
ggtagtccggcgcggtgaggtcgaagaacaa	Protospacer
* . ********** ******** ***  * 

46. spacer 5.37|1447648|31|NC_022997|PILER-CR matches to NZ_CP038239 (Leisingera sp. NJS201 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.742

gtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
ggtagtccggcgcggtgaggtcgaagaacaa	Protospacer
* . ********** ******** ***  * 

47. spacer 5.37|1447648|31|NC_022997|PILER-CR matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

gtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
gtccgtcgggcgcggtgaggtcgtctgtgtg	Protospacer
******* ****** ********.  .**  

48. spacer 5.37|1447648|31|NC_022997|PILER-CR matches to MT711977 (Streptomyces phage Dagobah, complete genome) position: , mismatch: 8, identity: 0.742

gtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
gtccgtccagcgcggtgaggtcggccgtgta	Protospacer
********.***** ********   .**  

49. spacer 5.46|1448832|34|NC_022997|PILER-CR matches to NZ_CP045223 (Achromobacter xylosoxidans strain DN002 plasmid unnamed) position: , mismatch: 8, identity: 0.765

-cagcagctcatgccgcgcggcgcactcgtgcaaa	CRISPR spacer
tccgca-ctcattgcgcgcggcgcactcgtggttg	Protospacer
 * *** *****  *****************   .

50. spacer 5.56|1449492|34|NC_022997|PILER-CR matches to NC_018696 (Paraburkholderia phenoliruptrix BR3459a plasmid pSYMBR3459, complete sequence) position: , mismatch: 8, identity: 0.765

ctgtgatcgcggagaagcaggaacaggtgatcgc	CRISPR spacer
acgtgatcgcggcgaagcaggaaaaggtactggt	Protospacer
 .********** ********** ****. * *.

51. spacer 7.2|2508872|31|NC_022997|CRISPRCasFinder matches to NZ_CP039918 (Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626a, complete sequence) position: , mismatch: 8, identity: 0.742

ctacgcagaattggtcgcgcttcgaggcccg	CRISPR spacer
ctccgcagacttggtcgcgcttctccgcaga	Protospacer
** ****** *************   **  .

52. spacer 9.1|2786478|32|NC_022997|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.75

ctgatggcgacgagcgtgccggacccgtacca	CRISPR spacer
ctgattgcgacgagcgcgccggaggccgccga	Protospacer
***** **********.******  *   * *

53. spacer 5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP035419 (Leisingera sp. NJS204 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

tgtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
gggtagtccggcgcggtgaggtcgaagaacaa	Protospacer
 * . ********** ******** ***  * 

54. spacer 5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP038239 (Leisingera sp. NJS201 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.719

tgtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
gggtagtccggcgcggtgaggtcgaagaacaa	Protospacer
 * . ********** ******** ***  * 

55. spacer 5.6|1447647|32|NC_022997|CRISPRCasFinder,CRT matches to MT711977 (Streptomyces phage Dagobah, complete genome) position: , mismatch: 9, identity: 0.719

tgtccgtccggcgcgttgaggtcgcagatgat	CRISPR spacer
ggtccgtccagcgcggtgaggtcggccgtgta	Protospacer
 ********.***** ********   .**  

56. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
cggcaccgcaggctgccggcgatgccgggcttcg	Protospacer
* **.***************** ****.  *  .

57. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 9, identity: 0.735

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
cggcaccgcaggctgccggcgatgccgggcttcg	Protospacer
* **.***************** ****.  *  .

58. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
cggcaccgcaggctgccggcgatgccgggcttcg	Protospacer
* **.***************** ****.  *  .

59. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 9, identity: 0.735

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
atcatcgccaggctgccggcgatgccgatgaggc	Protospacer
 *   *  ************** ******* ** 

60. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
cggcaccgcaggctgccggcgatgccgggcttcg	Protospacer
* **.***************** ****.  *  .

61. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
cggcaccgcaggctgccggcgatgccgggcttcg	Protospacer
* **.***************** ****.  *  .

62. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
cggcaccgcaggctgccggcgatgccgggcttcg	Protospacer
* **.***************** ****.  *  .

63. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP014686 (Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6b, complete sequence) position: , mismatch: 9, identity: 0.735

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
gagcgccgcaggccgccggcgaagcccagcagca	Protospacer
  ***********.********.*** *   * *

64. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to AP014720 (Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8) position: , mismatch: 9, identity: 0.735

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
atcaggctggggctgccggcgaggccgacgtaga	Protospacer
 *  * *  .******************.**.**

65. spacer 5.12|1448053|34|NC_022997|CRISPRCasFinder,CRT matches to AP014020 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C109A-MedDCM-OCT-S27-C18, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.735

cgaggggcaaaaccccgtgggcgaaggagcttga	CRISPR spacer
tgaccaaagaaacccagagggcgaaggagcttga	Protospacer
.**  .. .****** * ****************

66. spacer 5.12|1448053|34|NC_022997|CRISPRCasFinder,CRT matches to AP014021 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C109A-MedDCM-OCT-S44-C26, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.735

cgaggggcaaaaccccgtgggcgaaggagcttga	CRISPR spacer
tgaccaaagaaacccagagggcgaaggagcttga	Protospacer
.**  .. .****** * ****************

67. spacer 5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 9, identity: 0.735

agaccgtggggcagatgctcgaagccgtctggga	CRISPR spacer
cggtcgtggcgcagatgctggaagccgtctctac	Protospacer
 *..***** ********* **********  . 

68. spacer 5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 9, identity: 0.735

agaccgtggggcagatgctcgaagccgtctggga	CRISPR spacer
cggtcgtggcgcagatgctggaagccgtctctac	Protospacer
 *..***** ********* **********  . 

69. spacer 5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP039651 (Azospirillum sp. TSA2s plasmid p1) position: , mismatch: 9, identity: 0.735

agaccgtggggcagatgctcgaagccgtctggga	CRISPR spacer
cggtcgtggcgcagatgctggaagccgtctctac	Protospacer
 *..***** ********* **********  . 

70. spacer 5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NC_013860 (Azospirillum sp. B510 plasmid pAB510f, complete sequence) position: , mismatch: 9, identity: 0.735

agaccgtggggcagatgctcgaagccgtctggga	CRISPR spacer
cggtcgtggcgcagatgctggaagccgtctctac	Protospacer
 *..***** ********* **********  . 

71. spacer 5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 9, identity: 0.735

agaccgtggggcagatgctcgaagccgtctggga	CRISPR spacer
cggtcgtggcgcagatgctggaagccgtctctac	Protospacer
 *..***** ********* **********  . 

72. spacer 5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP053236 (Escherichia coli strain SCU-106 plasmid pSCU-106-2, complete sequence) position: , mismatch: 9, identity: 0.735

tggggtgatattcggcatggccggatcgggcggc	CRISPR spacer
tgtcactttcttcggcatggccggctctggcggc	Protospacer
**  ..  * ************** ** ******

73. spacer 5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP023734 (Escherichia coli strain FORC 064 plasmid pFORC64.3, complete sequence) position: , mismatch: 9, identity: 0.735

tggggtgatattcggcatggccggatcgggcggc	CRISPR spacer
tgtcactttcttcggcatggccggctctggcggc	Protospacer
**  ..  * ************** ** ******

74. spacer 5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP047380 (Escherichia coli strain CAU16175 plasmid pCAU16175_2, complete sequence) position: , mismatch: 9, identity: 0.735

tggggtgatattcggcatggccggatcgggcggc	CRISPR spacer
tgtcactttcttcggcatggccggctctggcggc	Protospacer
**  ..  * ************** ** ******

75. spacer 5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP024975 (Escherichia coli strain CV839-15 plasmid pCV839-15-p1, complete sequence) position: , mismatch: 9, identity: 0.735

tggggtgatattcggcatggccggatcgggcggc	CRISPR spacer
tgtcactttcttcggcatggccggctctggcggc	Protospacer
**  ..  * ************** ** ******

76. spacer 5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP025752 (Escherichia coli strain CV839-06 plasmid pCV839-06-p2, complete sequence) position: , mismatch: 9, identity: 0.735

tggggtgatattcggcatggccggatcgggcggc	CRISPR spacer
tgtcactttcttcggcatggccggctctggcggc	Protospacer
**  ..  * ************** ** ******

77. spacer 5.15|1448296|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NZ_MG904994 (Escherichia coli strain 14OD0056 plasmid p14ODV, complete sequence) position: , mismatch: 9, identity: 0.735

tggggtgatattcggcatggccggatcgggcggc	CRISPR spacer
tgtcactttcttcggcatggccggctctggcggc	Protospacer
**  ..  * ************** ** ******

78. spacer 5.22|1448758|34|NC_022997|CRISPRCasFinder,CRT matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 9, identity: 0.735

ccttcgcgaacagcaccgtcccgaacgttgcgat	CRISPR spacer
ccttcgcgaacatcaccgtctcgatcccgcctgt	Protospacer
************ *******.*** * .  * .*

79. spacer 5.25|1448955|34|NC_022997|CRISPRCasFinder,CRT matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 9, identity: 0.735

ttgatggtctcaggcaggtcggcgcgcgagatat	CRISPR spacer
ctggtggtctcaggcacgtcggcgcaggcggaac	Protospacer
.**.************ ********. * *. *.

80. spacer 5.26|1449021|34|NC_022997|CRISPRCasFinder,CRT matches to NZ_AP018921 (Pseudonocardia autotrophica strain NBRC 12743 plasmid pPA12743CP, complete sequence) position: , mismatch: 9, identity: 0.735

tttacgtcttcggcggtgacgatgcggacccggc	CRISPR spacer
ggtgcggcttcggtggtgacgatgcggatgcgtg	Protospacer
  *.** ******.**************. **  

81. spacer 5.26|1449021|34|NC_022997|CRISPRCasFinder,CRT matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 9, identity: 0.735

tttacgtcttcggcggtgacgatgcggacccggc----	CRISPR spacer
gatacctcgtcggcggtgacgatgcg----cggggtca	Protospacer
  *** ** *****************    ***     

82. spacer 5.45|1448766|34|NC_022997|PILER-CR matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 9, identity: 0.735

ccttcgcgaacagcaccgtcccgaacgttgcgat	CRISPR spacer
ccttcgcgaacatcaccgtctcgatcccgcctgt	Protospacer
************ *******.*** * .  * .*

83. spacer 5.48|1448963|34|NC_022997|PILER-CR matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 9, identity: 0.735

ttgatggtctcaggcaggtcggcgcgcgagatat	CRISPR spacer
ctggtggtctcaggcacgtcggcgcaggcggaac	Protospacer
.**.************ ********. * *. *.

84. spacer 5.49|1449029|34|NC_022997|PILER-CR matches to NZ_AP018921 (Pseudonocardia autotrophica strain NBRC 12743 plasmid pPA12743CP, complete sequence) position: , mismatch: 9, identity: 0.735

tttacgtcttcggcggtgacgatgcggacccggc	CRISPR spacer
ggtgcggcttcggtggtgacgatgcggatgcgtg	Protospacer
  *.** ******.**************. **  

85. spacer 5.49|1449029|34|NC_022997|PILER-CR matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 9, identity: 0.735

tttacgtcttcggcggtgacgatgcggacccggc----	CRISPR spacer
gatacctcgtcggcggtgacgatgcg----cggggtca	Protospacer
  *** ** *****************    ***     

86. spacer 5.1|1447325|34|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP017600 (Moorea producens PAL-8-15-08-1 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

taatgccccccacaaagcggcggccatgctcaat	CRISPR spacer
cgatgtcccccacaaagcggctgccatttatatg	Protospacer
..***.*************** ***** . .*  

87. spacer 5.9|1447860|34|NC_022997|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 10, identity: 0.706

ctgcgccgcaggctgccggcgaggccgatgtgga	CRISPR spacer
gcgcgccgcaggctgccgctgaggcccaggattg	Protospacer
 .**************** .****** * *   .

88. spacer 5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 10, identity: 0.706

agaccgtggggcagatgctcgaagccgtctggga	CRISPR spacer
cccgcgtggggcaggtgctcgacgccgtgggcgc	Protospacer
    **********.******* *****  * * 

89. spacer 5.14|1448230|34|NC_022997|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP034087 (Methylocystis rosea strain GW6 plasmid pGW6_1, complete sequence) position: , mismatch: 10, identity: 0.706

agaccgtggggcagatgctcgaagccgtctggga	CRISPR spacer
cgaccgtggggcagaccctcgaagcgtagctcga	Protospacer
 **************. ********    .  **

90. spacer 5.24|1448890|33|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.697

ggacgcatctgctgaacagactgccgggattga	CRISPR spacer
tggagcatctgctgaccagcctgccgggcggcg	Protospacer
 *. *********** *** ********    .

91. spacer 5.24|1448890|33|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 10, identity: 0.697

ggacgcatctgctgaacagactgccgggattga	CRISPR spacer
tggagcatctgctgaccagcctgccgggcggcg	Protospacer
 *. *********** *** ********    .

92. spacer 5.24|1448890|33|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP030127 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

ggacgcatctgctgaacagactgccgggattga	CRISPR spacer
tggagcatctgctgaccagcctgccgggcggcc	Protospacer
 *. *********** *** ********     

93. spacer 5.24|1448890|33|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.697

ggacgcatctgctgaacagactgccgggattga	CRISPR spacer
tggagcatctgctgaccagcctgccgggcggcg	Protospacer
 *. *********** *** ********    .

94. spacer 5.25|1448955|34|NC_022997|CRISPRCasFinder,CRT matches to NZ_CP019319 (Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-7, complete sequence) position: , mismatch: 10, identity: 0.706

ttgatggtctcaggcaggtcggcgcgcgagatat	CRISPR spacer
acgatggtcacaggcagggcggcgcggctcatgc	Protospacer
 .******* ******** *******    **..

95. spacer 5.26|1449021|34|NC_022997|CRISPRCasFinder,CRT matches to NC_022042 (Paracoccus aminophilus JCM 7686 plasmid pAMI1, complete sequence) position: , mismatch: 10, identity: 0.706

tttacgtcttcggcggtgacgatgcggacccggc	CRISPR spacer
tcgcagatatcggcggtgatgacgcggacccggt	Protospacer
*.   * . **********.**.**********.

96. spacer 5.47|1448898|33|NC_022997|PILER-CR matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.697

ggacgcatctgctgaacagactgccgggattga	CRISPR spacer
tggagcatctgctgaccagcctgccgggcggcg	Protospacer
 *. *********** *** ********    .

97. spacer 5.47|1448898|33|NC_022997|PILER-CR matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 10, identity: 0.697

ggacgcatctgctgaacagactgccgggattga	CRISPR spacer
tggagcatctgctgaccagcctgccgggcggcg	Protospacer
 *. *********** *** ********    .

98. spacer 5.47|1448898|33|NC_022997|PILER-CR matches to NZ_CP030127 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

ggacgcatctgctgaacagactgccgggattga	CRISPR spacer
tggagcatctgctgaccagcctgccgggcggcc	Protospacer
 *. *********** *** ********     

99. spacer 5.47|1448898|33|NC_022997|PILER-CR matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.697

ggacgcatctgctgaacagactgccgggattga	CRISPR spacer
tggagcatctgctgaccagcctgccgggcggcg	Protospacer
 *. *********** *** ********    .

100. spacer 5.48|1448963|34|NC_022997|PILER-CR matches to NZ_CP019319 (Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-7, complete sequence) position: , mismatch: 10, identity: 0.706

ttgatggtctcaggcaggtcggcgcgcgagatat	CRISPR spacer
acgatggtcacaggcagggcggcgcggctcatgc	Protospacer
 .******* ******** *******    **..

101. spacer 5.49|1449029|34|NC_022997|PILER-CR matches to NC_022042 (Paracoccus aminophilus JCM 7686 plasmid pAMI1, complete sequence) position: , mismatch: 10, identity: 0.706

tttacgtcttcggcggtgacgatgcggacccggc	CRISPR spacer
tcgcagatatcggcggtgatgacgcggacccggt	Protospacer
*.   * . **********.**.**********.

102. spacer 7.2|2508872|31|NC_022997|CRISPRCasFinder matches to NZ_CP039918 (Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626a, complete sequence) position: , mismatch: 10, identity: 0.677

ctacgcagaattggtcgcgcttcgaggcccg	CRISPR spacer
ctccgcagacttggtcgcgcttcctataata	Protospacer
** ****** *************  .   ..

103. spacer 9.1|2786478|32|NC_022997|CRISPRCasFinder matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 10, identity: 0.688

ctgatggcgacgagcgtgccggacccgtacca	CRISPR spacer
gccgtggcgacgatcgtgccggacgcggcgcc	Protospacer
 . .********* ********** **   * 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1987644 : 1997023	9	uncultured_Mediterranean_phage(75.0%)	tRNA	NA
DBSCAN-SWA_2	2558618 : 2617656	54	Paracoccus_phage(25.0%)	protease,capsid,tRNA,portal,head,tail	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_022997|1987644:1997023|DBSCAN-SWA
GATGATCGAAGACGCTGGAGAGATGGACGAGGCGCCGGGATGGGAAAGCCCCGACGGCGAGCTTCAGCCCGCCGCGTCGGAGGCGCTTATCGTGGATGTCGCGGGTTTCGAGGGTCCGCTCGACCTGCTGCTTGCGCTCGCCCGCACACACAAGATCGACATCTCGCAGATCTCGATCATGGCGCTCGTCGATCAATATCTCGTCTATATCGCGGAAGCCCAACGGCTCAAGCTAGAGATCGCGGCCGACTATCTCGTGATGGCGGCATGGCTGACGTTCTTGAAGTCGCGGATGATCCTGCCGCGCGAGCCGACCGACGACGAAACGCCGTCCGCCGAGGAGATGGCGCAACGCCTAGCATTCCGGCTCATGCGGCTCGAAGCCATGCGCCGCGCCATCGCGGACCTCATGACGAAGAAGCGGCTCGGGCAGGACGTGTTCCAGCGCGGGATGCCGGAAGAACGCTCGAAGGTCACGGATGTCCGGTGGACGGCCGAGATCTACGATCTTCTCAAAGCCTATTCGGAGCTTCGGCGGCGCACCGCCAAGGTCGTGCATGTGGTGAAAGCGCGCCGCGTGTGGTCGATCGAGAAGGCGCGGCGACAGCTCGAAACGCTCGTCGGCGAAACGGTCAGCGCCGGAGACTGGGTCCAGCTCGAAATGTGCCTCAGGACCTATCTTACGCCGCAGACGGTGGCCGAAGACGAGGACAAGACGGCGCTTGCAAGTTCGTTCGGTGCCACGCTCGAAATGGCGCGCGAAGGCTTGATCGAACTTCGCCAGGATGCTCCGTTCGAGGCGATTTACATGCGCAAATGCGAAGCAGGCGCTGCGTGGGAGCGGCTGGACCGACGGCATGGCGGTGTGGCGCCGTAGCCGTTTCGATGGCGCAACGGGAAAGGTAAGGCTGCATGGCTCCGCCGAGGCTGAGACTGGTGACGAGCGAAGGGACCCTGAATGCGCCCGAGGCGCAGGAAGCGATCGAGCTTGCGCGTGCGCTGGGCGAAGAGCTGGAGGGGGATGAGAGCGGGTCGTCTTCGGCATCCGTCGAGGGCGAGGTTCACATCGAAGATGTGCGGATCGTCGAGGCGCTGCTGTTTGCGTCTCCGGTGCCGCTCGACGACACTTGGCTCGCCGGACATCTGCGCCATGGCAGCGGCATTGCGAACGTGCTGGCAGAGATCAAGGCCGCCTATGCGCCGCGCGGCGTGAACCTCGTGCGGGTGGCGGGAAAATGGGTGCTGCGCACGGCGGAGGATCTCGGCTACCTGCTCGAACGCTATGCGGTCGAGGAGCGGCGTCTTTCGCGGGCGGCACTCGAAACGCTGTCCATCGTCGCCTACCATCAGCCGGTGACGCGCGCGGAGATCGAGGAGATCCGGGGTGTCACGACGTCTGCCGGTACGCTCGATATTCTGATGGAGGCTGGCTGGATCCGGCCGCGCGGGCGCAGGCGCGCGCCGGGCAAGCCGCTGACGTATGGCACGACGGACAGCTTCCTCGCCCACTTCGGTCTCGACAGCGTCAAGGATCTGCCGGGGCTCTCCGACCTTAAGGCGCAGGGGCTGCTCGATGGGCATCTGCCGCCGGGCTTCGCCATTCCCGATCCGACCTCCGTTGCGGCGCTGATGCCGGACGAATTGCCGCTCGAAGAAGCGGGGGAGGATGAAGGCTCGGCCGAGGACGAGGCGTCCGATGCCGAGGCCGACGGCTACGGGGATGACGACGCCGTGCCCGGTGACGGCGACGAGGCCAGCGACGTCGAGGCCGGGGAGGATCCCGACTTGCCCGGCGACGATCCCGACGCTAAACCGGACTAGCACTGTCGACATTGCGGCGCTCCCTCACCCGCTCGCTGCGCTCGCGACCTCTCCCCATCGGGGAGAGGCATAAGGAGCGAGAAAGGCGGGTGAGGGGGCGCCGCACGATCAACGCTGGGCGACCGAGACGCACGTGGCGAACTGGCTTTTCAATAAATCCTCGAACGATGCGGTTTCGAACGTGCTTTCGGAGGGTGGCCCTGTCCGTGCCGGGGCGACGTTCGCCGCCGAACTGCGCTTCGAAGAGGTCTCGAAGAACTATGGGGAGCGGGCTGCGCTCGCGGGGCTGTCGCTCGACATTGCGCCGGGTGAGGTGTTGTGTCTGCTGGGCCCTTCCGGCTGCGGGAAGACCACGCTTCTGCGCGTGGCGGCGGGGATCGAGCGTCCGGATGGGGGCCGCGTTCTGATCAACGGGCGGGAGGTCGCGGGGCCTGAGCGGTTTGTGCAACCCGAGGCGCGCGGCGTTGGCCTGATGTTCCAGGATTTCGCGCTCTTTCCTCATCTCACCATTCTCGAAAACGTGGCGTTCGGCCTCAAGGCGCTGCCGCGGGCGGAAGCCCGGCGCGAGGCGCTGACCGTGCTCGCGCGTGTGGGGCTTGAGCGGTATGCGGAGCAATATCCGCATATCCTGTCGGGCGGGCAGCAGCAGCGTGTGGCGCTGGCCCGCGCCATCGTTCCGCGCCCGGCGGTGATGCTGATGGACGAGCCGTTCTCGGGGCTCGACGTCCAACTCCGCGAGTCCATGCAGCAGGAGACGCTGGCGCTCCTTCGCGAGACGCGCGCGACGACCATGATCGTCACGCACGACCCCGAAGAGGCGATGCGCCTCGGCGATCGGATCGCGGTCATGCGCGCCGGGCGGCTGGTTCAGGTGGGACGGGCTGAAGACCTCTATCATCGCCCGGCGGAGTTGTTCGTTGCGCGGCTTTTCTCCGAGATCAACGAGATCGACGTGAAGGTTGCGGCAGGACGGGCCGCGACGCCGTTCGGTCCGGTGGCGGCGCCGGGGCTCGGGGACGGCGAGCGGGCGACGCTTTGCATCCGCGAGCGGTCCGTCGGGCTAACGGCGGTGCGGGCGAACGGGGGGGGAGAGGCGCAGGGGCTTGCCGGGCGCGTGCGCGACGCGAGGTTTCTCGGAGACGCGATGCGGCTCGAAGTCGTCGTCGAAGGGTTCGAAGCGCCGCTGAATGTCCGCACACGCGTCGGCCACGATGTCGCAAGGGGGAGCGAGGTGAGGCTTTGCATCGACCCAAGCGACGTGATCGTTTTTCCGTCGTCGAACGGTAAAGACACTTAAATCTCAAAGGATTGGAGCAAGGGTTCCGCCGCCGAGGCGCGCTTGCGACGGGGGGGTAATTCTGCAATAGTGCGTCGGCGAAACATGCGGTCTCTTACGCCGCGCGCGTGCCTCCGGCCCCGGGAATTGTTTTCGGATAAGAGGCACGACAAAACAAAGGACTAGTGTCTTTCGGCATCTCGGATGAATGCTGAAATGATACTGGAGGAGGTATTCCCATGGGGTTGAGTGCGACCCATCTCTTGATCCTTCTGCTCGTCGTCGTTCTCCTGTTCGGCCGTAACAAGATTTCGGACCTGATGGGCGACGTGGCGCGTGGCATCAAGAGCTTCAAGAAGGGTTTGGCCGAGGAGGAGGCATCGCCGCCGTCTCCGGCCGATCCCAAGGTGATCGACAACGCCGCGCAGGAAGCCGCCGAACGCGACAGGTCGAAGGCGGGCTAAGGCCGGTTCCGCTCGCTGGAGCGTGCTTGCGCGGCCCAAGGCCGCGAACGCGTGCTCTCAGTGGCCGTGCTGTGGGCCTGGTCCGCGCTCGCTTTTTCCGGGTTGGACGATCAGATGTTCGAAGTCAGTTGGAGCGAGATTCTTATCCTCGGCGTCGTCACGCTTTTGCTCGTGGGGCCGAAGGAACTGCCGCGCTTTCTTTCCTCGCTTGGCCGCCACCTCGGCGTGATCCGCAAACACGCCAACGAGTTCAAGGCCGTGTTCGAGCAGGCCATGCGTGAGGCCGAGATGGACAGCATCAAGCAGGAAATACGGGACATCGGCGACGGCGTGAAGAAGTCGTTCGACGATGCGACGCGCTCCGTCGATAGCGCGAAGGCGGCCATGCGCGTGGATCTCAATGCCAACACCGGCGTTCAGCCCAAGCCCGAGAGCCTTGCTAAAGCCGAAGCGAAGGCCGCCGAGGCCAAGGCCATCGCAGATGCTTCGGCTGCTGAGGAGCCGACGGAGGGCCAGCCGGACGCCGTCATTCCCGAGCGCGAGTTCGGAGTGCCGTCGTCGCCCGTTGCCGACGAACCCGTTCACGCCGAACGTCCGGCGGACGCTCCGAAGGGGTCCGGCTGATGCAGGATAGCACTCCCAGCTCCGGCCAGGACGACATCGAAGCGTCGAAGGCGCCGCTGCTCGATCACCTGATCGAGCTGCGCCAACGGTTGATCTATTCGGTTGCCGCGTTTTTCGTGATGTTCCTGCTGTGCTTCACAATCGCGCGCACGATCTACGACGTGCTCGTGTGGCCCTACGTTTGGGTTTCGGGGGAGCACCAGGTGCGGCTGATCGCGACGCACTTCCTGGAGCAGATCTTCACGCACCTGAAACTCGCGCTGTTCGGCGCGGCGTTCCTGTCGTTTCCGGTGGTGGCGACGCAGGTCTACAAATTCGTTGCGCCCGGTCTCTACAAGACCGAGCGCGCGGCGTTCCGGCCCTATCTGATCGCGACGCCGATCTTCTTCATCCTCGGCGCGATGGTCGTCTACTTCATCGCGATGCCGATCCTGATCCGCTTCTCGATGGGGCTTGCGCAGTCGGCGAGCGAGGGATCGGCGGCGATCGAGCTGATGCCGAAGGTGTCGGAATACCTGTCGCTGATCATGACGCTGATCTTCGGGTTCGGCATCTGCTTCCAGCTCCCGGTCGTGCTGACGCTGCTTGCGCGCATCGGCGTGGTGACGTCCGACATGCTGCGCAACGGGCGGCGCTTTGCTATCGTCGGCATCTTTGCGGTTGCGGCCGTGATGACGCCGCCGGACGCGATCAGCATGATCATCATGGCGCTGCCTACGACGCTGCTTTACGAGCTCGCCATCGTTTCGGTGGCCTGGGTCGAGAAGCAGCAGGCCGCCAAGGAGGCCGCCGAAGCGGCAGCCAAGACCACCTGACGCACCGGGCTACGAAACGAGTACGTGCGGCCGCCTGGACCTCTGTCGTCTCGCGCCTTATAGAGCGTGATCAGTCTTCACTGAATCGAGATCACGCTCTATCTCTTTGGTGAGACCTATGATTCACACTTCAGGCTGATAGGGCCTGAAATGATCATGGTCTAGCTCTCGGGACCTCGCAAAACCAACGACGCCAAGGACGGGCCACGTGTTCGACATCAAGTGGATTCGAGAGAATGCTAGAGCCTTCGACGAGGGCCTGAAGAACCGCGGCCTGGAGCCGGTGAGCGCGAAGCTCCTGGAACTCGACGAGGCGCGCCGCCGGCATCTCACGAAGTTGCAGGACGCGCAGAGCCGCCGCAACGCGGCGTCCAAGGAGATTGGCAAGGCCAAGGGCGCGAAGGACGAGGCGCTGGCCAGCAAGCTGATGGCGGAGGTGGCCGAGCTGAAGGAGGTCATCCAGTCGGGCGAGGAGGAGGAGCGTCAGCTTATCCACGCGCTCGAAGAGGCGCTCTCGGTGATCCCGAACACGCCGCGCGAGGACGTGCCCGTCGGCGCGGACGAAACGGAGAACGTCGAAGTGCGCCGTGTCGGCGCACCGCCCAAGTTCGACTTCACGGCGAAGCAGCATTTCGAGATCGGCGAAGCGCTGGGGTTGATGGACTTCGAGACGGCGGGCAAGGTTTCGGGCGCGCGGTTCGTCTATCTCAAGGGTGCGCTCGCGCGGCTCGAACGGGCGCTTGGGAGCTTCATGCTCGATCTCCAGACCGACACGTTCGGCTATTCGGAAACGAACCCGCCGCTGCTGGTGCGTGACGATGCGGCGTTCGGTACCGGCAACCTGCCGAAGTTCGCGGAGGATCTTTTTAAGACGGAGAACGGTTACTGGCTGATCCCCACGGCCGAAGTGTCACTCACCAACATGGTGCGCGAGCAGATCCTGGACGAGGACGCGCTGCCGATGCGGCTCACGGCATGGACGCCGTGCTTCCGCTCGGAAGCGGGGGCTGCGGGGCGCGATACGCGCGGCATGATCCGCCAGCATCAGTTTTCCAAAGTGGAACTCGTCTCCATCACCACGCCGGAACAGAGCCTCGACGAGCACGAGCGCATGACGGCGTGCGCGGAAGAGGTGCTGCGCCGGCTCGGGCTCGCCTATCGCACGGTGATGCTCTGCACGGGCGACATGGGGTTCGCGTCGCAGCGGACCTACGACATCGAGGTGTGGCTGCCGGGGCAGGACGCCTACCGCGAGATTTCGTCGTGCTCGGTGTGCGGCGATTTCCAGGCCCGGCGCATGGGCGCGCGCTATCGCGACAAGGCGAGCAAAGAGGTGCGCTTCGTGCACACGCTGAACGGCTCGGGTCTTGCGGTGGGGCGGACGCTCGTGGCCGTGCTGGAAAATTACCAGCAGGCCGACGGGTCCGTCATAATCCCCGAGGTGTTGCAGCCTTATATGGGCGGCATCACGCGGATCGAGCGGCCGGTGGGCTAAGCGGCGTGCCGCCAGCGGCCTTGACGGGTGTGTTAGACTTGAACGGCTCTGGGTCCCGGATCGCGAGGCGGGACACGGTGGCAGGTTCGATCGGCAGGCCTTCCGGCCGCCTCGCGTCCGGGATGACAGTGGGTAACGGCTGAACATGCGCATTCTGGTGACCAACGACGATGGAGCGGGCGCGCACGGGCTTTCCGTGCTGCATCAGATCGCGCGTCAGCTTTCGGACGACGTGTGGATCGTGGCGCCCGAGACGAACCAGAGCGGGGCCTCGCACGCGCTCACGCTTCAAGTGCCGCTGCGCTATCGCGAGGTTGGCGAGCGGGCCTTCGCCGTGCGCGGAACGCCGGCCGATTGCGTGATCATGGGCGTGAAGCACGTGCTCAAGGATCGGGCTCCGGATCTCGTGCTTTCAGGCGTCAATCATGGCGCGAACCTTGCCGAGGACGTGACCTATTCCGGCACCATCGCAGGGGCCATGGAAGGCACGCTGCTCGGCATCCGCTCCATCGCCATGAGCCTCACCATCGGGTTCGACCCGGAAGGCAAGCAGCATTGGAAGACGCCGCTTACGTATGGCGCACGTCTCGTCGAGCAATTGCTCGCGAACGACTGGCCGGCGGGTACGCTGATGAACGTGAACTATCCCGATCTCGCGCCGGGCGATGTCCGGGGCATTGCCGCGACGCGCCAGGGCCGCCGCGACCAGGGCGGTCTCAAGATCGAAGAACGCAGCGACACGTGGGGCACACCCTACTTCTGGGTGGGCTTTTCGCATCGCCGCTCCGATCCCGTGGAGGGGACGGACCTGCGTGCCATTGCGGACGGCATGATTTCCGTGACGCCGCTCTATCTCAACCTCACGCACGAGGCGACGCGCGAGGCGCTCGGCCAGACGCTGGCGCTGGATGGCGCCGGGCGTCTCAAGGATGCGGGCTGACGCTGCAATTTAGAGCCATTCCGGTTTTAGTGAACTCGCGGAATGGCTCTAAGTTTTTGCTTTATCGTGCTTCTTATCGGACACCGCCATCGCATGGCTTCGCCATGACCCGGTTCCCACTTTTCCGGAAGCACTCTAGGCAACCTTAAGGTCGTCAAGTCGCCGATATTTCTCCGTCATCGCAGCACAATCCACGCGTACTGATAAGGCTCCGGGGCCGGAATGTCCGGACAGAGCCGGCTGTCAGCCGTACCACGCCCCACACGAATCGCGTCGCAATGTTCAGCGCGCGTTAAGGACCCGTTAACGAGTTAAGGGTTACCTGAAGTGGGTATTTAGGGTGTGTGGCATGTTAAAGTCTTTGCGTAAATGTCATCGATCCTTCGGCGTGTCCGGCGGAGGTTCTGTGCTCGCCGTTGCCGCTGCGGCCGCGTTGGCGGGGTGCAGCGCGGATATTTCACGCTTCGATCTCGGCAACCCCGACGGCGCGCGCGTCCAGTCCGGCTACGCGCCGTCTGTGGGCATGAACGGCCGATCCACGTCGTCGGAATTCGGCACGGCCGCTCACGACCGGCCGTCGCAGCGCCCCTCGCAGGTATCGCGCTCCGACCTGCCGCCGCCGGATGGCCAGTTCACCACCAGCGCGCTCTCGCCTCAGTCGGACTCCTACGGATCGGGATATGGGCACCGGCCCGCGCAGCATCCGAGCCAGCAGGACTACGGTTCCAACCGCTATCAGTCGCCGTCTTACGGTTCGCCCGCGCCTTCGGGATATGGCGGATCGCGCGATGTCGCGCCCGTGGCCTCCTACGACAGCCGGGGCGGAGGCGATTCCATCGAGGTTCGCGCTGGCGATACGCTCTACGGTCTCTCGCGCCGCCATGGCGTCTCGGTCAACGACCTGATGCGGGCGAACGGGCTCACCTCATCGAACCTTCAGCCCGGCCAGCGTCTCGTGCTGCCGTCCGGCTCCGGTGCATCTCCGCAGCATCAGCCGGGCTACGAGACGCCGCGCGTCGCCGCTGCGTCCGTCGCGCCTGCGGCTCAGGCGCCGTCGGATTGGAGCGACACGTACACCGTGCAGCCGGGCGACTCGCTTTACGCGATCGCGCGGAGCAACGGCATCAGCCTTGCCGATCTCGAACGTTACAACGGCATTCAGGACTCGCGGCGCGTGATGCCGGGCACCGTTCTGCGCGTGCCGGGCGAGGCCGGGGCATCGACGCAGGTTGCCGAAGTGCCGCCGGCGTATCAGCCGCCTCCGGCCTATCAGGCTCCGGCCGCGCAACAGCCGATGCCGCGGACGACCATCGAAACGCGCCCGGTGCAGACGCAGGAGCACCGTCCCGCGCAAGAGGCGCGCAATCCAACCGGGACTGTGCGTCTCGGCGACCAGCGCGCGATGCCGCCGGGTTCCACTGCGCAGCAGCCGACCCTGCTTAACGGAGCGAGCACGCCGCCGGCGAACGGCGAGCAGCAGCGCGTTGCGCGTCTGGAAACGCCGGGTTCGGCGAGCGATGCCGTTTCGCCCTCGGCCCCGCAGCACTCCGGGTCCGTGGCGGGTTCGAGCAAGCTCCGCTGGCCTGTGGTGGGCAAAGTGGTCGGCGGTTTCGGACCGCGTCCCGACGGCACGCACAACGACGGCGTGAATCTCTCGGCGCCGATGGGCACGGACATTCACGCGGCTGAAAACGGCGTGGTGGCGTATGCGGGCGACGAGCTCAAGGGTTACGGCAACCTCGTTCTGATCCGCCACGACAATGGCTGGGTGACCGCCTACGCGCACGCCGACGAAATTCTCGTCAAGCGCGGCGACCGCATCAACCGCGGGCAGGTGATCGCGAAGGTCGGCCGCACGGGTCAGGTGGATCAGCCGCAGCTTCACTTCGAGCTGAGGCAGGGCCAGAAGCCCGTCGATCCGACGCCGTTCATGGAAAGAATCTGA

Protein sequences of DBSCAN-SWA_1

>NC_022997|1987644:1997023|1992851_1994138_+|WP_023787283.1|tRNA|DBSCAN-SWA
MFDIKWIRENARAFDEGLKNRGLEPVSAKLLELDEARRRHLTKLQDAQSRRNAASKEIGKAKGAKDEALASKLMAEVAELKEVIQSGEEEERQLIHALEEALSVIPNTPREDVPVGADETENVEVRRVGAPPKFDFTAKQHFEIGEALGLMDFETAGKVSGARFVYLKGALARLERALGSFMLDLQTDTFGYSETNPPLLVRDDAAFGTGNLPKFAEDLFKTENGYWLIPTAEVSLTNMVREQILDEDALPMRLTAWTPCFRSEAGAAGRDTRGMIRQHQFSKVELVSITTPEQSLDEHERMTACAEEVLRRLGLAYRTVMLCTGDMGFASQRTYDIEVWLPGQDAYREISSCSVCGDFQARRMGARYRDKASKEVRFVHTLNGSGLAVGRTLVAVLENYQQADGSVIIPEVLQPYMGGITRIERPVG
>NC_022997|1987644:1997023|1989597_1990761_+|WP_023787279.1|DBSCAN-SWA
MANWLFNKSSNDAVSNVLSEGGPVRAGATFAAELRFEEVSKNYGERAALAGLSLDIAPGEVLCLLGPSGCGKTTLLRVAAGIERPDGGRVLINGREVAGPERFVQPEARGVGLMFQDFALFPHLTILENVAFGLKALPRAEARREALTVLARVGLERYAEQYPHILSGGQQQRVALARAIVPRPAVMLMDEPFSGLDVQLRESMQQETLALLRETRATTMIVTHDPEEAMRLGDRIAVMRAGRLVQVGRAEDLYHRPAELFVARLFSEINEIDVKVAAGRAATPFGPVAAPGLGDGERATLCIRERSVGLTAVRANGGGEAQGLAGRVRDARFLGDAMRLEVVVEGFEAPLNVRTRVGHDVARGSEVRLCIDPSDVIVFPSSNGKDT
>NC_022997|1987644:1997023|1994283_1995078_+|WP_023787284.1|DBSCAN-SWA
MRILVTNDDGAGAHGLSVLHQIARQLSDDVWIVAPETNQSGASHALTLQVPLRYREVGERAFAVRGTPADCVIMGVKHVLKDRAPDLVLSGVNHGANLAEDVTYSGTIAGAMEGTLLGIRSIAMSLTIGFDPEGKQHWKTPLTYGARLVEQLLANDWPAGTLMNVNYPDLAPGDVRGIAATRQGRRDQGGLKIEERSDTWGTPYFWVGFSHRRSDPVEGTDLRAIADGMISVTPLYLNLTHEATREALGQTLALDGAGRLKDAG
>NC_022997|1987644:1997023|1991318_1991828_+|WP_081717843.1|DBSCAN-SWA
MFEVSWSEILILGVVTLLLVGPKELPRFLSSLGRHLGVIRKHANEFKAVFEQAMREAEMDSIKQEIRDIGDGVKKSFDDATRSVDSAKAAMRVDLNANTGVQPKPESLAKAEAKAAEAKAIADASAAEEPTEGQPDAVIPEREFGVPSSPVADEPVHAERPADAPKGSG
>NC_022997|1987644:1997023|1988555_1989464_+|WP_023787278.1|DBSCAN-SWA
MAPPRLRLVTSEGTLNAPEAQEAIELARALGEELEGDESGSSSASVEGEVHIEDVRIVEALLFASPVPLDDTWLAGHLRHGSGIANVLAEIKAAYAPRGVNLVRVAGKWVLRTAEDLGYLLERYAVEERRLSRAALETLSIVAYHQPVTRAEIEEIRGVTTSAGTLDILMEAGWIRPRGRRRAPGKPLTYGTTDSFLAHFGLDSVKDLPGLSDLKAQGLLDGHLPPGFAIPDPTSVAALMPDELPLEEAGEDEGSAEDEASDAEADGYGDDDAVPGDGDEASDVEAGEDPDLPGDDPDAKPD
>NC_022997|1987644:1997023|1987644_1988520_+|WP_041318210.1|DBSCAN-SWA
MIEDAGEMDEAPGWESPDGELQPAASEALIVDVAGFEGPLDLLLALARTHKIDISQISIMALVDQYLVYIAEAQRLKLEIAADYLVMAAWLTFLKSRMILPREPTDDETPSAEEMAQRLAFRLMRLEAMRRAIADLMTKKRLGQDVFQRGMPEERSKVTDVRWTAEIYDLLKAYSELRRRTAKVVHVVKARRVWSIEKARRQLETLVGETVSAGDWVQLEMCLRTYLTPQTVAEDEDKTALASSFGATLEMAREGLIELRQDAPFEAIYMRKCEAGAAWERLDRRHGGVAP
>NC_022997|1987644:1997023|1995484_1997023_+|WP_051388539.1|DBSCAN-SWA
MLAVAAAAALAGCSADISRFDLGNPDGARVQSGYAPSVGMNGRSTSSEFGTAAHDRPSQRPSQVSRSDLPPPDGQFTTSALSPQSDSYGSGYGHRPAQHPSQQDYGSNRYQSPSYGSPAPSGYGGSRDVAPVASYDSRGGGDSIEVRAGDTLYGLSRRHGVSVNDLMRANGLTSSNLQPGQRLVLPSGSGASPQHQPGYETPRVAAASVAPAAQAPSDWSDTYTVQPGDSLYAIARSNGISLADLERYNGIQDSRRVMPGTVLRVPGEAGASTQVAEVPPAYQPPPAYQAPAAQQPMPRTTIETRPVQTQEHRPAQEARNPTGTVRLGDQRAMPPGSTAQQPTLLNGASTPPANGEQQRVARLETPGSASDAVSPSAPQHSGSVAGSSKLRWPVVGKVVGGFGPRPDGTHNDGVNLSAPMGTDIHAAENGVVAYAGDELKGYGNLVLIRHDNGWVTAYAHADEILVKRGDRINRGQVIAKVGRTGQVDQPQLHFELRQGQKPVDPTPFMERI
>NC_022997|1987644:1997023|1991827_1992643_+|WP_023787282.1|DBSCAN-SWA
MQDSTPSSGQDDIEASKAPLLDHLIELRQRLIYSVAAFFVMFLLCFTIARTIYDVLVWPYVWVSGEHQVRLIATHFLEQIFTHLKLALFGAAFLSFPVVATQVYKFVAPGLYKTERAAFRPYLIATPIFFILGAMVVYFIAMPILIRFSMGLAQSASEGSAAIELMPKVSEYLSLIMTLIFGFGICFQLPVVLTLLARIGVVTSDMLRNGRRFAIVGIFAVAAVMTPPDAISMIIMALPTTLLYELAIVSVAWVEKQQAAKEAAEAAAKTT
>NC_022997|1987644:1997023|1990979_1991204_+|WP_023787280.1|DBSCAN-SWA
MGLSATHLLILLLVVVLLFGRNKISDLMGDVARGIKSFKKGLAEEEASPPSPADPKVIDNAAQEAAERDRSKAG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041318210.1|1987644_1988520_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	2.5e-29	32.3
WP_023787278.1|1988555_1989464_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	5.0e-41	47.6
WP_023787279.1|1989597_1990761_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-29	34.9
WP_023787280.1|1990979_1991204_+	twin-arginine translocase TatA/TatE family subunit	A0A1B1IVR9	uncultured_Mediterranean_phage	1.1e-05	59.1
WP_081717843.1|1991318_1991828_+	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_023787282.1|1991827_1992643_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	3.4e-49	45.2
WP_023787283.1|1992851_1994138_+|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.2e-104	47.9
WP_023787284.1|1994283_1995078_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	2.1e-43	41.7
WP_051388539.1|1995484_1997023_+	peptidoglycan DD-metalloendopeptidase family protein	Q8SBN9	Clostridium_phage	7.7e-18	35.3

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_022997|2558618:2617656|DBSCAN-SWA
CTCACGTGCCTACGCTGGCTTCGCCCGCCACTCCGTTGCTGCGCAAATCAGGCGCGGTCGCTTCGTCCTTTAAGGACGCCAGCGCCTCATCCAGCGTCATCACCGTCTGGGCTTGGGAGCCGAGGCGGCGGATGGAGACTTTGCGTTCTTCGGCTTCGCGCTTGCCGACGACGACGATCACCGGGACCTTCGCGAGGCTGTGCTCGCGGACCTTGTAGTTGATCTTTTCGTTGCGGAGATCGCTGTCCACGCGCAGGCCTGCCGCGCGCAACTCAGCCACCACGTCGAGCGCGTACTCGTTCGCATCCGACACGATGGGCGCGACGACGGCCTGCAAGGGCGCAAGCCACAGCGGGAAGTGGCCCGCAAAGTTCTCGATCAGGATGCCCGTGAAGCGTTCGAGCGAGCCGAACATCGCGCGGTGAATCATCACCGGCGTTTTCTTCTCCGAGTTCTCGTCGATGTAGAACGCGCCGAGGCGGCCCGCGAGGTTGAAGTCCACCTGCGTGGTGCCGCACTGCCATTCGCGGCCGATGGCGTCGCGCAGCACGTATTCGAGCTTCGGTCCGTAGAACGCGCCCTCGCCCGGCTGCAGCGCCGTTTTCACGCGACCGTTCGAGGCGCGTTTCACTTCCTCCAGCACGTCGGAAAGTGCGGCTTCCGCCTTGTCCCACAACTCGTCGGAGCCGACGCGCTTTTCAGGCCGCGTCGAGAGCTTGATGAAGATGTCCTCGAAGCCGAAGTCCTTATAGATCGCGAGCATGAGGTCGTTGATCTTGAGGCACTCGTCCTTGATCTGATCCTCGGTGCAGAAGATGTGCGCGTCGTCCTGCGTGAAGTGGCGCACGCGCAAAAGCCCGTGCAGCGCGCCCGACGGCTCGTAGCGGTGAACTTTACCGAACTCGGCGATCTTGAGCGGCAGGTCGCGATAGCTCTTGAGGCCGTGCTTGAAGATCTGCACGTGGCCGGGGCAGTTCATCGGCTTGCAGCAGAACACGCGCTCGTCGGGGAGCGTGGTCGTAAACATGTTCTCGCCGTAGTTTTCCCAGTGGCCGCTGAGCTCCCAGAAGTGCTTCTCCATCATGTCGGGAGAGTTCACTTCCGTGTAGCCCGCACGCTGTTGGGCGCGACGCATGTAGCCGATCAGCGTCTGGAACAGCGTCCAGCCCTTCGGGTGCCAGAAGACGGAGCCCGGCGCTTCCTCCTGGAAGTGGAACAGGTCCATCTCGCGGCCGAGGCGGCGGTGGTCGCGCTTCTCGGCTTCCTCGATCTGGTGGAGGTAGGCCTTGAGCTCATCCTCGGTGGCCCAGGCGGTGCCGTAAATGCGCTGAAGCTGCGGCTTCGTGCTGTCTCCGCGCCAATAGGCGCCCGCAAACTTCATCAGCTTGAAGGCTTTGCCGATTGCGCCCGTGGACGTCATGTGCGGTCCACGGCAGAGGTCGAGCCATTCGCCCTGTTTGTAGATCTTGAGGTCCTCGCCCTCGGGAATCGCGTCCACAAGTTCGATCTTGAACAGCTCGCCCTTGTCGCGGAAGAAGCGCTTGGCGTCGTCGCGCGACCAGAATTCCTTCGTGAACGGCGCGTTCTTGGCGATGATCTCGCCCATCTTCTTTTCGATCTTCGGGATGTCGTCGGGTTCGAACGGCTCGGCCTTGGCGAAGTCGTAGAAGAAGCCGTTGTCGATGACGGGGCCGATGGTGACCTGCGTGCCGGGCCATAGGGCCTGCACGGCCTCGGCCATGACGTGGGCCGCGTCGTGGCGGATCAGCTCCAGCGCTTCCGGGTCGGTGCGCGCGACGAACTTGATCTCGGCGTCTTGCTTGATGGGGTCGGCGAGGTCGGAGAGCACCCCGTTGAGGGTCATCGCAACCGTGCGCTTGGCGAGGGAAGGCGAAATCGACTTTGCGATCTCAAGACCTGACGTTCCTGCGGCGACCTGGCGGCTCTTGCCGTCTGGGAACGTGATCGTAATTTCGGATGCTTCCGACATAGGTTCGGCTCCTCTCACTCGCGGCTTACCGATCCGCGTAAGATTATGGAGCCGCTTCCTTCCTCGGAAACGGGCGCCGAGTCAAGCGGGCTGCCTTCAGTGGGCTCCGAGCTTGGCCAGACCCGCTTTGCTGTCCGCATAGGCCGGATCGATGGCGAGCGCCGCGCGAAAATCGCGGATCGCGGCCTCGCGGTCGCCGAGGGCTGCATGGATGTGAGCGCGCGTGTCCCATGCGTAGGCCTGCTTCGCGAGGAGCCGCACGGCGGCATCCGCATCGGGCAGCGCGTCGCGTGCGCGCCCCATGCGATAGTAGGTCCAGGCGCGATTGTTGAGAGCCTCGCCGTTGCGCGCGTCGCGCCGGATGGCCTCGGAGTAGTCCGCAATCGCGGCGTCGAAGTTCTGCTTCTTGTAAAGCACGGTGCCGCGAAGCGCGTAAGCGGCCGGCGTCGGCGCAATCGAAAGCGCGGTCGTGATGCTCGACAGCGCGCGGTCGAAGTCGCCGCGATCGCGCAGCGCCTTGCCTTGGCGCAGGTGGAACTCCGCAAGCTCGGCGTCCTGCGCCAGTCCGCTGTCGATGAGAAGCTGGCAGCCTTCGATGGCCTTCGACGGTTCGCCGCCTTCGCAATCACGCCAGGCATTCGGCAGCATCTTCCTGGCCGATAACACGGCCGAGGGGTTGGGTGCGTGCGCGGGCTTGAAGACGAGCGTCCCGCTCGGACGTGCGTCTGCGGGCGGCGTGGATGCAGCGGTGACATCGGCGCTCGACGGCCCGGGGAGAGGCAGGCCCGCTTCAGCAGGCCCATCGGCAGACGGCTCAGGTGCAGGCTCCGAACGCGGGAGGACGAGCCACGCCAACGCGCCGATCAGGAGCGCTGCCGCAACGGACGCGGCATGTTTCGGCGCGACACTCCATTGCGGAAGCGCCCGTTTCCGACGGGCTGGCTCAGCACTCCCGACAGCGACGCGATAGGTCGCGGGCGCCAAGCCGTCGAGCGCGGCGCCATCGGGCGTGACCGGCTGAAACGCGAGATGCAGCTTGCCCGCCACGGCCTCGCGCAACGATTGGGACACGCAGAGGCCGCCGGGGGCTGCGAGGTCGGCGAGGGCGCGGACGGCAGCGTGCGTTTCCGGCGGCACCTCGCCCTCGCCTGCCGGGACCTCGGCAATGGCGATGCCGATCCGTACGTCCATTCGCTCGGTGAGAGACAGCGCCTTGTTGCGCGCCCGCAGGGTCTCCTGCATGTCGACGGCAGCGCGCATCACCGCGACTGCGCTTTGGAAGGCTGCGATCAGCGCGCCTTCATCGCTCGCCGTCAGCATCTCGCCGCCGCCGTGGGCGACGACATCGCGAACGACGGCGCGGTAGGAGTCGAGGCGCACCGGAGCGCCGGGGTCGTCCGCGCTACCGGACGAACGCGCGGCGGCGATGTCGGCCATCAGGACGGCTCTGATCTTGCGCTTCAACGGTTCGTCCTCGAAGGGCGTCCGGGCTCAGAAGCCGCGACGTGCCGGCCTCTCAAGCCTCTTCACTCTCGGGCACCCTAACATGGCGAACGCCCGATGCCGTCGCCTCCGACGAGGATACCGCTAAGAGATCTCGGAGGGCGGGACACTCCGCTTGCGGCTCCAGCGGCCGTAGCGCCAGGGGGCAAACGTGTGCTGCTCACCCTGAATGTCGGGGACGGGATCGTAGCCGGAGCTGCCCCAAGGATGACACCGAGAAAGGCGGGATGCCGTGAGCCACAGGCCGCGCCATGCGCCGTTCTTCTCGATGGAGCCGATGGCGTATTCCGAACAGGTGGGCAGATGCCGGCATTCAAGCCCCATCAGCGGCTTTAGTGTCCAGCGATACGCGTGAATAGGGGCTTGGAGCAGCCGCTTGGTCCAACTCATGTCAGCACGCCCTCGCCTCGTCCGCGTTCTCAGGCCTCGACACCCGGCCTTGGCGTGGCCGCTCCGCGTTTCGCCTCGACCTCGTCGAGCGCCCGCTCCACCGCCTCGAATACGAGCAGCGTGGAAGCGTGGCGGTGGGGATAGTCCTTGACGGGCTCCAGCAGGCCGAGATCGGCCCAGCGCCCCTCCGGCCGGGGCCGCCCTCCTTCAGCATGCGCCGCATGGCGTCGGCCACGGCGCGGAACTCCGCTTCGCTCGTGCCCACGATTTCACGCCCGACAATGGCCGCGGAGGCCTGACCCAGGAGACATGCCTTCACCGATTGACCGAAGTCCGCGATGCGGTTGCTGTCGAGTTTGATCTCCACCTCGACGGTCGAACCGCAGAGCTTGGAGTGGGCGCGCGCCGCGGCATCGGGACGATCGAGGGGCACGGCGCGCGGCATGGCCGCCGCCAGCTCGAAAATCCTCTGGTTGTAGATGTCGTCGAGATCCGCCATGGGTTTCCCGTCAGATGCCTTTTTCGTGCCGCACGACCGGAGGCATAGGGCTCCCGGCCGTCCTGGTCTATATATATGCCGTCTGAGCCAGCCGTTCGAGTTGCATCGGAATACTCATGATCGACACATCCCCTTCACCCCCTGCGCGCAACGCCGCAAAGGCCGAAGTCGAGCAGGGCGCGCGCTTTCTGCCGAAGCTCGACAGCGATGGCCTGATCGGCGCAGTCGTCACCGATTACGACACAGGTACGGTGCTGATGTTCGCTTGGATGAACGAGACGGCGCTGAAACTGACGTTCGAGACCGGAATCGTGCATTTCTGGAGCCGCTCGCGGGCACGGCTTTGGAAGAAGGGCGAAGAGAGCGGCAATACTCTGCACCTGCGCGAGGCCCGCGTCGATTGCGATCAGGACATGCTTTGGATTCGCGCCGATGTCGCGGGCGCGGGCGTGGCGTGCCACACGGGCGCGCATTCCTGCTTCTATCGGACGATTTCGACGGATGCCGACGGCACGCTCGTTCTTACGCGCGACGAGATTTAACCCAGTCTCGCCCTCGGTAGGGGGCCTTTAATCCGCATCTGATAGGCTCCACCTATGATGGAGGGAGTGTTCGTCGCCTTCCGCGGCGGGTCCCAAGGGAGACATCATCGCCGGCCTCGCCCTCTGGGGGAAGGGCTGGAGGAATGGAGGCCCCATGCCTGCCACCAACGGTGCCGGCAACGTCAAGATCGGTCTTGCGCTCGGCGGAGGAGCGGCCCGAGGCTGGGCGCATATTGGCGTCCTGCGCGCGCTGAAGAAGGCCGGAATTCAACCTGACATCATCGCAGGCACATCCATCGGCGCCGTCGTCGGCGCCTGCGATGTCGCCGGACATCTCGACGAACTCGAAGCCTTTGCGCGGGAGCTCACCCGGCGCCGTGTGCTCGGCTATCTCGATTTCAACCTTTCCGGCACGGGCCTCATCACAGGCCATCGCCTTGGAGAGCGCCTTTACAAGCACCTCGGCGATATGCGCATCGAGGACCTGCCGCGCAGCTTCACCGCGGTTGCGACCGAGATCGGCACCGGGCACGAAGTGTGGCTGTCGCGCGGGAGCGTGGTCGATGCGGTGCGGGCTTCCTATGCGCTACCCGGCGTGTTCCGCCCCGTGAAGGTGGACGGCCGCTGGCTGTTCGACGGTGCGCTCGTCAACCCGATCCCGGTCTCCGTCTGCCGCGCTCATGGCGCGCGGTATGTGATCGCCGTCAATCTCAACATCGACATCTCGAACCGCGGCACCATTTCGAACATCAACCCCATGCCGCAGTCGGACGGCGAAATGGAAGCCGTTCCGCCGGTCACCGGCAATAACGGCATCGCGGTTCGGCGCCTGCTTCAGCGGCAGATTCTGGGACGCGGCGACGACACGCCGGGCATCACGACGGTGATGGTGGATGCGTTCAACATCGTGCAGGACCGCATTGCGCGCTCGCGGCTGGCGGGCGATCCGCCGGACGCCATGATCAGCCCGCGGCTTCACGGAATCGGTCTGTTCGATTTCTATAAGGCGGAGGAACTGATCGCGCGCGGCGAAGCGGCGGCCCAGCGCACGATCGAGGATCTCGCACGCGAACTCGAAACGCGCCGCGCGCTCGAAAGCGGAGCGGCGATGCCTGCGCATTGACGTTTCAATCGGGTGACGCTCCCTGTGGCGGGCGGCGTTTTTAATTCGGAAATGAAAAACGGCGCGTTGGCAAACGCGCCGTTTTCTATTCCTTTGCATAGCGAGAGTGGCGTCGTCAGCCGGTCGCGAGATAATTGCGCATGGCGGAGACTTCCATCTCGACCTCGGCCACGTGGTGGTGCACCACGTCGCCGATCGAAATGATGCCGACGAGCGCGTCGTCCTCGATCACCGGCAAATGACGGAACCGGCCTTTCGTCATCATCTCCATCAGCTCGTCGAGCTCGCTCGTTTCGCCGCATGCGATGACGTTGCGCGTCATAACGTCGGACACCACCATACTCAGCGCCGCCGCACCGTGCTCCGACACCGCACGAATGATGTCGCGCTCGGAAATGATACCGGTAACGTGGCCGTTGTCGCCCACCACAACCACGGCGCCGATCTTCTTCGGGCCGAGCTTCTTGGCGACATCCAGCAATGTGGCGTTCGGCCTTGCTGTCGTGACCGCGCGTCCTTTCGCCTTCAGTATCGATGCAACGTTCATGACGTTTCCTCCCGCTCGCTGTCGATCAATGCGCGCCGTGCCGTCGACGGACGTTCTCCTCCCGTCCTCACTCACGCGTACTGACTGCCACGAGCGTTTTTTTCCTCGTGTCTTCTTTGGCCGAGCCACAATCGTGCCTCGACAAACTCAAGAGTGAGGCAAACTTCCGAAACGCGCAAGAGTTTCAATCCGTGTCGAGTTGCGGATCATCTGCGAAGCGGGAAACATCGTCGAAAAGACCATAAGTAAAGATCCCTATCGCATAGCCACCGAGATGCGCCTCCCAAGCAATGCCCGCTGAATTTTGTGCAGCGCCAAAACCGATGATCGTCAGAACATTTATAAGCACCAGAACTGCACTGGTGACGATCACCCGACGGTCGGTCAAAGTCTCCCCGAGCGGCATCAGCGGAATCGAACGCGGCGCTTCGCGCAAACGCCGGAAGCCCCCGTTATTCATGGCCGGAAACAGAATACGGAGCGTTCCGCCTAGGAGGCCGGAGATCGCGCCGGACGCCCCGATCATGGGCGTCATCTGGCCCTCGTTGGCGATGTAGAACGCCAACGCCCCGCCGAGCCCCGAGAGGATGAAGAACGCGAGGAAACGGACCGCCCCCGTGCGCGCCGCTATTGCGCCGCCGAAGGCGAGAAGCCAGGCGGAATTGAGCGCGAGATGAATCCAGTCGCCGTGTACGAGCATGTGGGTAAAGGGCGAGGTGAGCTTGGCCAACTCGCCTCCCGGAAGCACCTCGCCGAGCGGACCGTAGCGGCCGGGGATGAAGGCTGAGGCCAGCACGAACCACAAATCGCCTTCGGACGTCAGCACGGTGCGGCCCAGGTGGACCAGCACCAGGACAGCCAACACGCCGACGACACAATTCGGGACATTAAATACGGGCTCTTGAGACGTATCCGTCGGGGTCACGCAGGTCTCCTCAGTTCATGGGGCCTCGGACCCCTGTCATTGGGGGTCTTCGCTCTACGAGCCGGCTTTCGGCCGGCCTGTCGCCGTCCGTTCCGGCTCTCCCTCGTGCATATGGCACGGAAGCTGCTTTTGTCGACGGCATGGGCCGTTTTCGGGACGCTTTCGTTCTCCCGGCAGGCCGCATTTCGAGAGCATCCGCTCTTGTAAGGCACGGGCCGCAGTCTTCTGCGGCGCCGGAGGAGTATTGCGTGCAAGCGGTCGCTCAGTTTCAACATCGTGCCACACAGGCCCTTTACGCCTATTGGAACGACGTCCGGGCCGGCCGGCGGGCGCCGAGGCGGCTCGAAATCCAGCCAGCCCAGCTTGGAGGCCTTCTGCTCGATACCTTCATTCTGGAGCGCACGGACCGCTCGACCTACCTGTTCCGCCTGGCTGGCACCCGGGTTTCCAACTGGCTCGGCGCGGATCTCAGAACCCGCAACTTTCTCTCCTGTTGGGGCGAAGCGGACCGGGCCATGCTGGAACGCCACCTGGCCGCAATTTCCGAACTGGGACGCGTCGGCGTGTTCACCGGCGAGGGCTATCTTTCCGACACCGCGGCCCCGGCCGGATCTCGCGCCGCAGCGTCTTTCGAGCTGATCGTGTTGCCGCTCATGCACACGGGGCACGCGATCGACCGCTTGCTCTGTCTTCTCGTTCCCCTCGACGACAGGGCCGCCGACGCGCATAGCCCGCGCCGAGGGCTCAAGCTTCTTGCGGCCGAAGAGATCTGGCCGGAGGGCGTGTCGCGGGAGCCCTTTATGGATCCGCCGCCCGCTCTCAATCCGAATGTCCGCATGGCCCGGATCGTTCGCCAGGGGCGACGGCAGTTCCGCGTGTATCAGGGCGGACGCGTGGGCGAGGCGCCGCAGGCCGACGCCGAGCGGCCGTAGCACGGCAACCTTTTTTGGGGGCCGATCCCACCCGCCACCGGGCACCTCCGGCCGCGATCCTTCCTAACATCGCCGACATCGACCTCGCACCGGGCCGCAGCGCGCACCGGGCATGCCTGCGTGCGACTTTGATCCAGCGGTTAGGCGTTCCTTAAACCTGTTGTCTCATTCTAGGACTCCCTCTGCGCGGAAACGGCTCAAATGCCGTTTCGGTCATGGGGGGTGCCGTCAAACGTTACCGCCCGGAATTCGCTCATGTCCGCCAGTCCAGCCAATCACATCCGTTCCTCGATCCGGCTCGACACGAGGATCGTGCCCGACAGAAGGCGCCACAAGCGCTTTCACCTCGCGCTTCTTGGCCGTTTCATGCGCGCCAACAAGCAGGAGTTTCCTTGCAGGCTCAACGATATCTCGGTGGGAGGTGCGGCCGTGATGTCGCCCGTCGAGGTTGAGATGGGCGAGCGCATCGTTGCCTACTTCGACGAAATCGGCGGGCTGGAGGGCGAAGTGGCCCGGCTTTTCGACGGTGGCTTCGGCATGCGCTTCCGCGTGAGCCAGCACAAACGCGAGAAGCTCGCGGCTCAGATCACATGGCTGGTCAACAAGGCCGAGCTCGGCGACAGCTTCGGCCGCAAGCACAAACGCTTCGAACTGGTCAACAAAACGTCAACGTTGAAGCTCCCTGACGGCTCCTCCGTCGATTGCCGGGTGCTCGACGTTTCACTGTCGGGCGCCTCCATCGGAACGGAGGCGCGGCCGTCGCCCGGGGATGTGGTGATGCTCGGGAAACTGCGGTGCAAGGTCATGCGTTATCACGACCGCGGGATTGGCGTGCAATTCCTCGACATTCCAGATCCAGAGGCTTTGCGGCGCTATTTCGGCTGAACGGGGCACCCCGATCTCTCACTTCATGAGCATCAGTTTAGCTCAAATTTTGCTCGATTTCTGGCGGCGTACTTCAGGGGACCGCGAAACTTCAAGGGTACTGTGGTCGGCGTGACAGGGAAGTAGGGGTAACGCGTATGAAGCGTATTTTCATGTGCATCGCGGCAATGGCCGCTTTCGCCGGACCGGCCGGTGCCATGCCGGACGTGGTCGTGCCTGAGACCAACACCAGCAGTTCTCCGTTCATGCGGGTCTACGGTCCCGCGCAGCCGCCCTACGGGTTCGTCCGCTTCTGCGAGCGCAACCCGGATGCCTGCCGGGCGCGCCACATCGAAGACATCCGCTTTCAGCCCACGCCCGAGCGCTTGAGCGAACTCGACGAGGTCAATCGCTGGGTCAACCACGCCATCGCGCCGGCTACCGACATGGAGATTTACGGGGTCAGCGAGTTCTGGACCTTCCCCGTCGATCGCGGCGACTGCGAGGACTACGCACTCCTCAAGCAAAAGATCCTGATCCAGCGCGGCTGGCCCAAGAGTTCGCTTCTGCTGACGGTCGTGCGCGACGAGAAGGGTGAAGGCCATGCCGTGCTCACCGCGCGCACCTCGCAGGGCGACTTCGTGCTCGACAACAAAATCGACGATGTGCGCCTCTGGAATGCGTCCGGCTATTACTTTCTGATGCGCCAATCGTATCTCGATCCGCGCGTGTGGGTGTCGCTCGACGTCAACGACCGCACGGCGCCGGACGCCATCGCTGGCGTGCAGGACGGGCGTTAAGACGCCCGGCACGCTCAACGCTTCACGTTTTCACGACCCTTGTCCTGACTGACGACCCCCCGAGCCCGGCGACCCTGCCCTTGTCCCCCAACCGGGCTCCCCCTTGAGCCGGACGCGATTCTCCCTCGTGTCCGGCTCTATTTTTTTGCTTCGTACGCAAGCTGTGAGAAGCTTCGGATAACGGGCGGGTGCCGGTTGATAGCCGGCGCACTTGCGCCGGGTCGCTTTGCTCCCGGGCGCTATCGCGCCGGTCTCTTCTTAAGGTGCGCATGCTGCGTCCCCCTGCTGGCGGAGGCAGGTGTTACGGTGCCGGGCGGAAACCTGCCTTGTAGCGCTTCCAGTTCGCGACATAGCGGCCCGCGCCTTTGCCGAAGCGGGCGACATCCTCGTCCGTGAGCTCGCGTACGATCTTGCCCGGAGAGCCGAGCACCATGGACCGCGGCGGGATCACCTTGCCCTCGGGGATCAGTGCGTTGGCACCGATCACGCATTCCTCGCCAATCTTGGCGCCGTTGAGGATGACCGCGCCGATGCCGATCAGACTGCCCCGGCCGATGGTGCAGCCGTGCAGCATCGCCATGTGGCCGACGGTGCAGTCCTCCGCGATGTCGAGCGGGAAACCGGGGTCCGTGTGGAGCACGCAGCCGTCCTGCACGTTCGAGCGCGCGCCGATGCGGATCAGCTCGTTGTCGCCGCGCAGCACCGCCCCGAACCACACGCTCGCGTCGGTTTCGATCCGCACCTTGCCCAGCACGACCGCATTGGGCGCAACCCAGAAGTTGCCGTCGGCCGGGGTTTCGACGCGCGTGTCGTCGAGGTCGTAAAGTGCCATCCGTCAGTGCCCCTCAAGCCTCTTCGAGATCCATCTCAAGGATGGCCATCTGGAACTGATAGGACACTTCGCCCTCTTCCTCCTCGCGGAACAGCACGGCGACGAAATCGTCTCCGATATAGACCTCGGCACTATCGTCCTTCTTGGGACGCGCCCGCACCGACAGGTTCTTCGTCCCGAATGTCTTCCTCAGATACGCCTCGACCTTGGCCAGCTCGTCCTTCTTCACTCTGTCATCCTCCGGTTTCGTTAGTTAGACCGGCGATTCACGCTTCAGGCTGATAGGGCCTGAAGCGATCGCGGTCTAGAGCATTGCATAATCATCGGGCCCGATCCCGGGATCGGATTCGAACGTCTGGTCCATCGTTCGTCCGGGTTCCGCGCCAGCCGGGCCGACGATGCGCGCCGGCACGCCGGCAACCGTCACATGCGGTGGGACATCCGAGAGCACCACCGAGCCCGCGGCGATGCGCGAGCTGTTTCCCACGTGAATGTTTCCGAGCACCTTGGCGCCGGCGCCGATCAGCACGCAGGAGCCGATCTTGGGATGGCGGTCGCCCGTCTGCTTGCCGCTGCCGCCCAGCGTCACCGCGTGCAGGAACGAGCAGTTGTCGCCGATGGTCGCCGTCTCGCCGATCACGATGCCGGTCGCATGGTCCAGCATCAACCCCTTGCCGATACGCGCTGCGGGATGGATGTCGACCGAGAACATGCGCGACGACTGGCTTTGCATGTAAAGCGCAAAGTCGCGCCGGCCTTGACGCCACAGCTCGTGCGCAAAGCGATGCGTGACGAGGGCGTGAAAACCTTTGAAATAGAGAAAGGGATCGAGATAGCGCGCCGTTGCAGGATCGCGCTCGATTACGGCTGCGAGGTCGGCGCGAAACGCGCGGCCGAGTTCCGGCTGGGACGCGAGCACGTCCCGGAACGTCTGGACGATGAGGCCCGCGTCGACGTCCGCATGGCCGAGGCGCTGCGCGATGCGATGGCAGATCGCATCTTCCAGGTTCTCATGGCTCGCGACGGTTGCGTAGATGAACCCCGTCAGCGCAGGCTCGGCCGCCATCGCAGCTTCCGCCTCGCTGCGGAGCGCCAGCCAGATCGGATCGTCGCCAGCGCGGCGGGAGGGCGTGCGCCGCTCGCCCTTTCCGGCCTGGACCGGCTGCTTGGCACTGTTCATGTCCACTGTTCCTTCGTACGCCGCGACCCGAACGGGTGTGCGCCGCCTTCGTCTCACGCGCGGGCCGTCGTGCGACCGGACCCTCATGCGAACTATGGATCAAACCGATCCTCGCGTCAGGCGGTTCTCGCCATGTCATGGGGAGGGCCTATCGGCCGAGGCGGGCCTAGTCAATCCTTTAGCGCTTTGTCCTGGCCCATACTTTGGGCGTTGCGCCGCGTTGCTCGGGAGCGCATCGAAGGGCACATTGAGAGGGTACCGAAGAGGACCAGCCGACATGACCGATACTCCCGCCACACCGCCCGATCTCAGGCTTGAGATCGAGGGTCCCCTCGCCTGGATCGTTGCCGACAATCCCGGCCGTATGAACGCGTTCACAGCCGACATGTGGGCCAAGTTGCCGCAACACATTCAAGCCGCGGAGGCAGATGCCGCCGTACGCGTCATCATCCTGCGCGGTGCGGGGACGCGGGCGTTCTCCGCAGGGGCCGACATCTCTGAATTCGAAAGCGCGCGCACGGGCGCCGCCGCCGCCGACTACGACCGCCTCAACCACGAGGCGTTCGACGCTCTTCTCGGCGCGAGCAAGCCGGTGATCGCGATGATCCACGGCTTCTGTCTCGGCGGCGGCCTCGGCATCGCGGCGTGCGCCGACCTCAGGCTCGCAGACCATCGCGCGCAGTTCGCCATTCCGGCCGCGAAGCTCGGTCTCGGCTACAATGCCCGCTGGGTGCAACCTCTGCTCGCACTCGCCGCTCCCGCCTTCGTGAAGGAGATGCTGTTTACGGGCCGGCGGGTTTCGGGCGAGGAAGCGCTCAGGATCGGCATCGTCAACACGCTGACCGATGCGGATACGCTGGAGATCGCGGTCCGAACGCTTGCGGCCGAGATCGCAGGCAACGCACCGCTCACCGTCAGCGCCGCCAAGCTCGCCATCGATGAACTCACCCGCCATCCCGAGCAGCCCGACTTCGCGAAACTCGATGCCGCCGTGCTCGCGTGTTTCGAGAGCACGGACTATGCGGAAGGGCGCCGGGCGTTCCTCGAAAAGCGCAAGCCCGCGTTCCAGGGCCGCTGACGCTCACAGCCAGCGAATTTTGAATCCCGTCGCAGGACGGCGCCACAACCGCGCAAATTCATTCCAGATTTGGGGATCGCACCCCGCACTCATGCTGCGTCGCACGATCATTTTCGCTTGGCAGGGAACGATCTTGCTCCGTACACTTTATGCCTCGGCGGGGTCCCTGCCTCGCCGGGGCCGCCTCGTCCCGGGCGGAGCACACTCTGCAAACGGTGTGTGGGACACGTTCCGACCTACGTGTCCGGCGCATCTTTATCTGCGTGTTTGACGAGCAGTCCCCCCCAACGCCGATCCGTCGGCAGGAGGTCGCGCATGGAACTCTCGATCCGACTGACGGTGCTCGCCGCACTCATGTCCTTCGGCTTCCTCGCTGCAATCGTGATCGGACTGGTCTGAGCACTCCCTGTCTCTCAGACGAGGCCGATCAGGAGCCGGTTCAGCTCATTCCCGCGCATCGCTTGTGCGGGGCACGCAAAAGGAAAGGCGCGAGACCCTCGGGTCCCGCGCCTTTTTCTTTGACGGCGCTTGTTGTGCCGCCGCTACCTTTTCAGATGATAGCCGAGGATCGCGAAGGCGAGCACAGCGTACTCCGCGCGGATGCGGCCCCAGGGGATCTCAGACAGCAGCGGGAGTTGCGGACCCCATGTCCACAGCACGGCGGCGATCAATGCAAATCCCAGCGCCCAGCTCAGTGTCGCGCTCGACGGCGAACCGACATCTTTCAGAATGACGGCGGCGATGATCCCGATCAGGAAGATCACGACTGCGGCGACCACCGCGAAGATGAACAGGCGGAACTCGCCGAATTTGATGTAGTTCATGAGCGCCGTCGTGCCGAACCAGCCGACGGCGATCTGCAGCAGCAGAAGAATGAGACGTCCGAGCATCGTGAGTTCTCCCCCAGTTTCGAGAGCCGGCCTTCCCCACCTGCCGACATCACACGCACCCGACCTTCGATATGAGGTCAAGGGCGCAACAATCGCATCACGCACGAGAATCGAGGTGTCCCACGCGCTTGCGATGCAGCATGGCCGCCCACGGTGCGAAAATCAAGAATTGCGGACGGCGCCTCATGCCACGTTCTTGGCTTCGGCGACCGCGTCGTAATTGAGGACGGGCGCGAGCCAGCGCTCCGCTTCCGCCACGCTCATGCCCTTGCGGCGGGCGTAATCCTCGACCTGGTCGCGCTCGACCTTGCCCACGCCGAAGTAATGGCTTTCGGGGTGTGCGAAGTAGAGACCCGACACGGACGATCCCGGCCACATGGCGAAGCTCTCCGTGATCTCGATGCCCGTTTCCTCCTTCACGCGCATCAAATCCCAGAGCGTGGCCTTCTCGGTGTGATCGGGCTGTGCGGGATAACCGGGCGCGGGGCGGATGCCCTGATACTTTTCGAGGATCATATCCTCGTTCGAGAGCTTTTCGCCCTTGCCGTATCCCCACAGCTCGCGGCGGACCTTGGCGTGCATCGCCTCGGCAAAGGCTTCCGCGAGACGATCGGCCAACGCCTTGGCGATGATGCGGCTGTAGTCGTCGGTCGCCTTGATATGTGCGTTGATCGCCTCGTCCTCGCCATGCCCGGCGGTGACGGCGAAGCCACCAACGTAATCGGCAAGGCCGCTCTCCTTCGGCGCAACGAAATCTGCGAGCGCGGTGTGGGCGCGATTGCGGCTCGGATCGCGGGCGATCTGCTGGCGCAGCGTGTGCAGCGTGGCGCGCCGCTCCTTCCGCGTCTCGTCGGTATAAAGCTCGATGTCGTCGCCCACGCCGTTGGCCGGCCAGAAGCCGACGACCGCGTGCGCGGTGAACCACTTCTCGGCGACGATGCGGTCGAGCAATTCGCGCGCGTCGGCGAAGAGCTTGCGCGCCTCGGTGCCCACCTTGTTGTCGTCGAGAATGGCCGGATAGCGGCCCGTCAACTCCCACGTCTGGAAGAAGGGCGTCCAGTCGATGTAAGGGACGAGGCTTCCGAGATCGTAGTTCTTGAAGGTGCGCGTACCGAGGAAGCTCGGCTTCGGCGGCGCATACTGCGACCAGTCGATGTCGAACTTGTTGGCGCGTGCCGCGCTGATGGGAATGCGCTGCTTTCTCGCTTCGTTGGCAAGGTGCTTTTCGCGCACCTGCACGTACTCGGTCTTGATGTTCTCGATGTAGGGCTTGCTCTCGGTCTCCGAAAGCAAGTTCGAGACGACGCCGACGGCGCGGCTCGCGTCCAGTACGTAGATGGCCTGGCCGCGCTCGTAGTTGGGACTGATCTTGACGGCGGTGTGGACGCGGCTTGTCGTGGCGCCGCCGATGAGCAGCGGCACGCTGAAGCCTTCGCGCTCCATCTCGGCCGCAACGAAGCACATCTCGTCGAGCGACGGCGTGATGAGGCCCGAAAGCCCGATGATGTCCGCCTTCTCCTTCTTCGCCGCTTCGAGGATCTTGGCGGCCGGCACCATCACACCGAGGTCGATCACCTCGTAGTTGTTGCACTGGAGCACGACGCCGACGATGTTCTTGCCGATGTCGTGCACGTCGCCCTTCACGGTCGCCATCACGACCTTGCCGGCGGCCGGCATCTGGTCGACGCCGGAAAGGCGCTTCTCTTCCTCCAGGTAGGGTTGCAGGTAGGCAACCGCCTGCTTCATCACGCGCGCGGACTTCACGACCTGCGGCAGGAACATTTTGCCCGCGCCGAAGAGATCGCCGACGACGTTCATGCCCGTCATCAGCGGGCCTTCGATCACATGGAGAGGCTTCTCGGCCTGCTGACGGGCTTCCTCGGTATCCGCTTCGATGAAGTCCGTGATGCCGTGGACGAGCGAGTGCGTGAGGCGCTCCTGCACCGTGCCCTCACGCCAGGAGAGATCCTTCTCCTTCGCTTTAGCGCCGCTGCCGTCGCCTTTGAAGCGCGGGGCCGCTTCGAGCAAACGATCGGTCGCGTCGGGACGGCGGTTCAGGATGACGTCTTCCGACAGCTCGCGCAATTCGGCCGGAATGTCGTCGTAGAGCGCGAGCTGTCCGGCGTTGACGATGCCCATGTCCATACCAGCCTTGATGGCGTGGTAGAGGAACACGGCGTGCATGGCTTCGCGCACGGGCTCGTTGCCGCGGAACGCGAACGACAGGTTCGAGACACCGCCCGAAATGTGGGTGAGCGGCATCTTTTCGCGGATCTGGCGCGCGGCCTCGATGAAGGCGATGCCGTAACCGTTGTGCTCCTCGATTCCCGTCGCGACGGCGAAGATGTTGGGATCGAAGATGATGTCTTCCGGCGGAAAGCCGACCTGCTCCGTCAAGATCTTATAGGCGCGCTCGCAGATCTGGACCTTGCGCTCGATGGTGTCGGCCTGGCCCACTTCGTCGAAGGCCATGACGACGACGGCCGCGCCGTAACGGAGAACCTTCCTCGCCTGCTCGACGAACTGCTCCTCGCCTTCCTTCATCGAGATCGAGTTGACGATGGCCTTGCCCTGCACGCATTTGAGACCCGCCTCGATCACGGTCCATTTGGAGCTGTCGATCATGACAGGCACGCGGGCGATGTCGGGCTCGGAGGCGATGAGGTTCAAGAACGTCGTCATTGCCTTTTCGGAATCGAGCAGGCCCTCATCCATATTGATGTCGATGACCATGGCGCCTGCTTCGACCTGCTGGCGCGCAACGGCCAGGGCCGCCGCGTAGTCATTCGCTTCGATGAGCTTCCTGAACTTCGCAGAGCCCGTAACATTGGTGCGCTCGCCGACGTTGATGAAGGATTGCGCTGCGGAAGAGGTCATCGGCTGGTATTCCGTGTTGGTTTCATAGGAGAAAGCGAGAGGGGCTTGCCTTATGCGAAGGCAAGCCAGCCCTTGATGGCAAGGCCGCGGAAGATGGGCGTCAAGCGCTCGAAGCCTGCGCTTGCAAGCAGCGCTTCTTCACGCTCTTCCGACACCACGGCGACTTTTTTGAAGTTCTCAGCGTTGCTTTCCGCCACGTCGGGCGAGACGCCGTTGCAGACGGCATGGCGCTTCCAGATGCGGCGTAGAAGCTCGGTCTTGTCTTCGCCCGCGACACCGACGCCATCCACGATCGCAAGCGGTGCCCCGGGTTTCAGCCTGCTGTGAATGGCCTTCAAGAAGGCCGCCTTCGCGCCGTCGTCAGGGACGAAGTGTGCCGTCAGAATGCACGTCGCGGCATCGAAGCCGTCGTCTTCGAGCGCCTCGATGGTTGTCGTCTCCACACGGGCGCGGGCCCCGACCGGCGTTTCGGCGAGGCGGCGATGCGCGAGTTCCACCATCGGCTGATAGGTGTCGACGCCCACGAACGACCAGTTCGGATTGTTCGCGCCAAGGCGCAGGATTTCCTCGCCGCCGCCCGCGCCCACGACAAGGATCTTGGACGGGCCGTCGGCAAGAAGCTCAAGAAGTGCGGCTTCGACAATCGAGAAGATGGCGCGCCGGCCGGGAATGAACTGTTCGGCCAGCTTCGCGTAATCGTCGAGCGTCACGTTCTCGGGAAACTTCTGGTCCTCGAACTTGAGTGTTGTCATTGCGTCACCCGTGCACGAAGGGTTCGAGACCCGAAAGCCGCATTTTCGGTGCGATCTCGGGGATCTCGCGCGGGCGATACTTGGCGGCGCGCGCGGCAATCTCACGAATGTGGTCGGGCGTGGAGCCGCAACAGCCGCCGATCAGATTGATCAGTCCGTCCTTGGACCAGGGCTCGGTTTTATCCGCCATCTCTTGCGCGTCCTCGTCGTATCCGCCCATCGCGTTCGGAAGGCCGGCGTTCGGATATGCGGAAATGCGCACGTTCGCGACCTGCGAAAGCTCGGCGACGTACGGGCGCATCAACTCCGCGCCGAGTGCGCAGTTGAGACCGATGGAGAACGGCCTCAGGTGGCGCATCGAATACCAGAACGCTTCCGCGGTCTGGCCCGAGAGCGTGCGGCCCGAGCGGTCGGTGATGGTGCCCGAGATCATGATAGGGAGCGTCAGACCCTTCTCGTCGAACGCTTCCAGCGTCGCGACGCCGGCGGCCTTCGCATTCAGGGTATCGAAGATCGTCTCGATCAGGATGATGTCCGAGCCGCCCTCGATCAGGCCCAGCACCTGCTCCTTGTAGGCTTCGCGCAGATCGTCGAACGTGACGTTGCGGTAGCCTGGATTGTTCACGTCGGGCGAGAGGGAGGCCGTGCGGTTGGTCGGACCGACCGCCCCCGCCACGAAGCGCGGCTTGTCCGGCGTCTTCGCGTTGTACTTGTCGACGGCCGCGCGCGCGAGCTTCGCCGCCGCGACGTTGATCTCGTAGGACAGCTCCTCCATGCCGTAGTCGGCCATCGAGATCACCTGCGCGTTGAAGGTGTTGGTCTCGACGATGTCGGCGCCGGCTTCGAGATACTGTTCGTGAATCTCCTGGATGATCGCGGGCTGCGTCAGCACGAGAAGGTCGTTGTTGCCCTTCACGTCCCGCGGCCAGTCCTTGAAGCGCTCGCCGCGATAATCTTCCTCGGTCAGCTTGTGGCGCTGGATCATCGTGCCCATGGCGCCATCGATGATCAGGATGCGCTCGCTTGCTGCTTTTTCGAGCGCTTCCGCGCTCTCGATGACTTTCATGGTCTTCCACTCAGGTTCGAAACGAAGGACTTGCCCGCAGCGGCGGCGCGCCGGGACATTCTGAAACGTTCAGCTCGCGGCTTTGCGGGCTTCGAGCGGTGCCGCCCGCAGCGGGCGCAGGCCCAGAAGGTGGCAGATCGCATACACGAGGTCGGCGCGGTTCAGCGTGTAGAAGTGGAACGATTTCACGCCTTCGTCGACGAGGTCCATCACCTGCTCGGTCGCGACGGCTGCCGCCACGAGATGGGTTGTCGCCGGATCCTCGTCCAGACCTTCGAAGCGCCGCGCCAGCCATGCCGGCACGCTCGCCCCCGTACGCACGGCAAAGCCCGCGACCTGACGGAAGCTATGGATCGGCACGATGCCGGGCGTGATCGGCACCCAGATGCCGGCTGCGCGCGCGCGTTCGAGGAAGCGCAGGTAGTGCGTGTTGTCGAAACCGAACTGCGTGATGATGCGGTCGGCGCCCGCATCGACCTTGGCCTTGAGGTTGTCGATGTCGGACTTGAGCGACGCGCTCTCGGGGTGCTTCTCGGGATAGCCCGCCACGGAGATTTCGAAATTGGCAATGCGCTTCAGGCCCGCCACGAGATCGGCCGCGTTTTGATACCCACCCGGGGTCGGGATGTAACTCTGGCCGACACCGCTCGCAGGGTCGCCGCGCAACGCCACGATATGGCGAACGCCCGCGTCCCAGTAGGCCTGCGCCACGGCGTCCACTTCCTCGCGGCTTGCATCCACACAGGTGAGATGGGCTGCAGGCTTCAGCGCCGTCTCGTTGATGATGCGCGCAACCGTCGTGTGCGTCCGTTCGCGCGTCGAGCCGCCCGCACCGTAGGTGACGGAGACGAACGACGGGCAGAGCGGCGACAGGCGTTCGATGGCGGCCCACAGGGCCTGCTCCATCTTCTCCGACTTCGGCGGGAAGAACTCGAACGAGACGTCGATCTCACCTGCGCCGAGGAGGCGGCTTTTGCGTTCGCTGGTTTGCGGGGTCATGGCGCGATCCGTTCCAATTTCTGCGACTTGGATGCCGGTTGCACGGCAACGTCTGGTTTCGATGCCCGCCAGAGCGAAACCGTGAGGGCTTGGCGGGCATCGGTGGCGTCGGGCGCGAGGCTCTGCACCTCTACACCGGACAGGCCCGCATCCTTGAGCCAGGATACGACCTGCCGATCCTCGAAGCCCAACCGCTCGTGGGCGTGGCGGGCGCGCAAGTCCTCGATCTCGTGCGGCGCGAAGTCGACGACGAGCAGGCGGCCGCCGGGGGCCAGAATGCGCGCGGCTTCGCGGACGGCGAGCGCGGGCTCCGAGAGATAGTGCAGCACCTGGTGCATCACGACGGCGTCCGCCACACGATCCGGCAGCGCGAGATCGTAGATGTCGCCGTGGCGCACCTCGGCGGCCGCAAGCCCGGCCGTCTTGAGACGGCTTCGGGCGTAGGCCAGCATCGACTGGTTGACGTCGAGGCCAAGGCCGCGCGTGTAGCGGCCGGCGAAGAGTTCGAGCATCCGGCCGGTGCCGGTGCCAAGATCGACGAAGACGTCGAACGTCGCGCCGTCGAAAGCTTTCACGATGGCGGCGTCGACCGCATGTTCCGACACATACAGCGCGCGAATGCGATCCCAGTCGGCGGCGTGCGCACGGAAATACTCCTGCGCTGTCGCCTCGCGCTCGCGCTTCTGGGAGTCGGCACGCTCGCCGTCGCGCAGGAGGATGGGGTCGCGCGGGTCGACGGTGTCCAGCAGGCGGCGAACGAGGCGCCCCCCCTCGGTGCGGTCGGAGACATGGAAATAGACCCAGCTTCCCTCGCGGAAGCGCTCGATCAGACCGGCCTCCGCGAGCAGCTTCAAATGCCGGCTGATGCGCGGCTGGCTTTGACCCAAGATCTGGGTGAGATCCTTGACGTTGAGCTCGCCTGCCGCGAGCAGGAGCAGGATGCGCAAACGCGTGGGCTCGGCGGCGGCCTTGAGGGCGCCCACCAGCTCCTGCGTATCGAGTGTTCCAGACATGCGCTGCTCCGCGTTTCTCGAAAACATATAAAGATATGTTTATGTGTCAAGAGGCATTCGGTCGATATCTTGAGGGCGAAGGCTTGGTCAGCACTCATCCCTAACCTATTATTAGCGCATGATTTTTTATCGTTGCCGAAGGATTTTTGAGGGCGCGACGGATCGGAACGGCTCGATCCGCCCCGATGTGGAGGTCGAACCCGACAGACCTTCGACTCCCGGCACGACCTCGCCGCCAGCGTCGGCCGAGGCTCTCCCGCTCGTCACGCGCGCGCTCACCCAAGACTTTTCACGGCTGCCGAAATTTCGTCCCGGGACGCCGCTAGGCTCGTGCAGCTCGACAGGGTGGTTCCACGTTCGGACCTTCAGCCAAGCCCGACCCGGATCTACGATCGCGGCTCGCGCGGCTTTGACTGGACAACGCATGCGGGCTGAGAGATTGAGGGGTAGCCGTATGCCTCAGGAAGGCACCCGGTTCGCGCCGAAACAGCGGGAGCTCATTTGATGACGATGGTTGGCCAGAGCCGGTTTCACGGCAGAGCGGCATACGTGTTTGGAGCGGCGGCGCTCGCGCTTCTCGTTCTCGTGGCCAGCACGATGTCGGCTTCGGCACAACAGTCGCCCGCCGCCTACATGCAGCGCGTCGCCAACGAACTGATCGCCGCCCAGCGCTCGGGATCACAGGCCGATTTCGCGCGCGTCATTCGCAGCCATGCCGACGTGCCGTCCATTGCGATCAATGCGCTCGGCTCCTACGCGGCCAGCCTCAAGAAGTCCGACCGGCCCGCTTATTACGCTGGCATGGTCAATTTCATCGCGCGTTACGCAGCAACGGAAGGGCCGAAGTACCCGGTCGCACGCGCCGTGATGACGGGCCAGACCAGGGAAACGGCCCAGGGTACCTTTGTGGACAGCCGCATCACGCTTTCGAGCGGCACCAGCTACGACGTGCGCTGGCGCATCGTGCGGCGCGGCAGCGCCTACAAGGTTCGCGATGCGGAAATCATCGGCTTCGAGATGACCTCGTTCCTGAACACGCTGTTCCAGAACTACATCTCCGAAAACGGCGGCAACCCGCGCACACTGGTGCTCGCGCTCAACCGATAAGTTCACGGCAACGCGAAAGCCGCGGCTTTATCCAGCATTGCGTTCGTGCTCCGGCTCATGTCATGTCGGTCGCGAAATCGACGCCATCGTTTTTCGTGATCCGCGGATGACGTCGCACTCTCACGTCGTCGTTCCGGAGCTCCGATGAAGACCGCGCCGCCACGCCCCGCCGCCTCAAAGACTACCGGCCGCCCGCCTATCTGGTGGATCACGTCGACCTCGACGTCGCGCTCGATCCGGAAGCGACGCGCGTTAAGGCCCAGCTCAAGATCCGGCGCAATCCGGCCGCGGAAAAGGGCGCTGCAGCGCTCGCACTCGACGGCGAGCACCTCGTGCTCGACGCCATCACACTTGACGGCAAGCCGCTTCCCGAGCGCGCCTACGATCTCACCGAAACGGAACTCGTCATTCATAAGGTGCCGGCTCGTCCTTTCACGCTCAGCGTCGAGACGACGATCGACCCGGAAGCGAACAAAGCGCTGCAGGGGCTTTATCGCTCGCGCGGCGTGTTCTGCACGCAATGCGAGGCGGAGGGCTTCCGCCGCATCACCTTCTTCCCCGACCGTCCCGACGTGCTCGCGACCTACACCTGCCGCATCGAAGCGGATCGTGCGACGGCGCCGATCCTGCTCGCGAACGGCAACCCCGTCGAACGCGGGCGTCTCAAGGGAGGCCGCCATTTCGCGGTGTGGCACGACCCGCATCCCAAGCCCTCGTATCTTTTCGCGCTCGTCGGCGGCGATCTCGGGCGCATCGGCTCGACATTCAAAACCGCATCGGGGCGCAAGGTCGACCTCAACATCTACGTGGAGCACGGCAAGGAAGAGCGTGCAGCCTGGGCGATGGATTCGCTCAAGCGCTCCATGCGGTGGGACGAAGTCCGCTTCGGGCGCGAATACGATCTCGAAGTGTTCAACATCGTCGCCGTGTCCGACTTCAACATGGGCGCGATGGAGAACAAAGGCCTCAACATCTTCAACGACCGGCTCGTCCTCGCTTCGCCCGAAACGGCAACGGACGACGCCTTCGGGCGCATCGAGAGCGTGGTCGCGCACGAGTACTTCCACAATTGGACCGGCAACCGCATCACGTGCCGCGACTGGTTCCAGCTTTGCCTGAAGGAAGGGCTCACCGTCTATCGCGACCAGGAGTTCTCCGCCGACGAGCGCTCGGCCACGGTGCAGCGCATCCAGGACGTGCGCACGCTGCGCGCGACGCAGTTCGCCGAGGACGCGGGCCCGCTCGCGCATCCCGTGCGGCCCGAGAGCTATATCGAGATCAACAACTTCTACACGGCGACGGTTTACGAGAAGGGCGCGGAACTGGTCCGCATGATCGAGACGATCCTCGGGCGCGACGCCTTCCGCGCCGGGATGGATCTCTATTTCGAGCGCCACGACGGCTGCGCCGCGACAATCGAGGATTTCATCGCGTGCTTCGAAGACGCCTCGAAGCGCGATCTGTCTCATTTCAAGCTCTGGTACTCGCAAGCGGGTACGCCCGAACTCGTGTGCTCGCTCGCCTACGACCGGCACAAGAAATCGGCCGAGCTTAAAATCGAGCAAGCGTTGCCTCCCACGCCGGGCGACGCACGCAAGAAGCCGCTGCACATCCCGATCCGAGTGGGTCTCATCGGCGGCAACGGGCAGGAGATCCCGCTCGTCCGCGACACCGGCGAAGCGATCGAGGATGGCGTGCTCAACCTCACGCGCCGTTCCGAGACGTTCCGTTTCGTCGATGTCCCCTCGGCGCCCGTGCCTTCGCTGCTTCGCGGCTTCTCGGCGCCGGTCAATCTCACAATGAGCCTTTCGGAATCCGATCTCGCGTTCCTGATGGCGCACGACCGGGATCTGTTCAATCGCTGGCAGGCCGCCAACACGTTCGCAACCCGCACGCTCGTCGACATGGTGCGGCGTCTCAAGAAGGGCGAGCGGGCGACACAACGGGCGACGGCATTCGCGCGCGCGCTCGAAGCGGCCGTCAGCGCGCCCGATCTCGAACTCGCGTATCGCGCCGAACTTCTCAAACTGCCGAGCCAGAGCGACATCGCGCGCGAGATCGGCCGCAATGTCGATCCCGGACTCATTTTCCGCGCGTATCGCCAGCTCACGCGCGTCGTCGGCTCGACGCTGGGTGCACAGCTCGAAGACGTTTATCGCGCGACGCGGGATCGTGGCGCGTTCTCTCCCGATGCGGAGAGCGCGGGACGGCGCGCGCTCGGGAACGTGGCGCTCACGCTGCTCGCCGCGCGCGGGACGGCGGCGGACGTCGAGCGGCTTTCGGACCATTTCTTCAACGCGCGCAACATGACGGAAGAAGCGCACGCGCTCGTGTTGATCGCTGGGCGTTCCGGCACGCTGCGGGAGGAGGCGCTCGCGCGCTTCCACGACCGCTGGAAAGACGATCACCTCGTGATCGACACCTGGTTTGCGGCTCAGGCGCAATCGCCGCTCCGCGCAGCGTTGAGCCAGGTGAAGGCGCTCACGCGCCATCCGCTGTTCAGCCTGACGACGCCGAACAAGGTCCGCGCGTTGATCGGCGCGTTCGCACTGCAAAACCCGGTTCAGTTCCACCGGCCAGACGGCGCCGGCTACGACTTCCTGGCTGCCCAAGTGCTTGAAATCGATGGCTTCAACCCGTCCATCGCAGCCCGTCTCCTGGGCGCTTTCCGAGCCTGGGCGACCCTCGAATCCGGCCGCCGGGCCGCAGCCAAAAAGGCTCTCCAGCGGATCGCAAAGGCCGGGTCTCTTTCCCGCGACGTGACCGAAATCGTAGCTAAGATGCTAGATCAGTAACACTCCGAAAATCTCTGACTCTTCTGAATTTTTCTCCCTCGACACGAGCCACACGAATCGGTGAACTAAGGGTGCGCTTCGCCGTCGTACCGCGCACGTAAAGCTCAAAAATTCGAATTTGGAGGATGGGATGGCTCAGACCCTGTCGGCTTGTCCACGGGAGACGTGTGCCCCGACCGATCAGGCGGTCGCCATCCGGCCGATCCCGGCCGCGCTCGCCGGATTCCGGGACGGTGGCGGCCCTCTGCGCCTCCTCCAGGCGGCGACGCTCGTCCATGCCGGCGCCCTCGCGCTGCCCCTTGCCACACCAATCGAACTGCCCGTTACGGCCCTTTTGGCGGGCGCCTCGCTCACGGCGTTGCTCGCGCTCGCACTGCCGCGGCTTTCCGCGCAGCCGGCCGAAGAGGCGCGCAAAGATGGTCCGGCAGACGTTGCCACCGACGATCTCTCCCCGAAGGTTGAGGGCAGCGGGGCATCGCCCTCCCCGCTGCCCTTCATAGGAGAACGGATCGTGCCCGGCCGCGACGACACGGCACAACTCGCAGTCCTCGCGCGGGCGGCGCAGCGGCTCAGGCGCGTGTCTCCCGTCCGCCGACAGATTTGGGCCGACCTGACAGCCCGCGTCAGCCACGAGTTGCGCACGCCTCTCAATGCCGTGATCGGCTTCTCCGACGTCCTCGACGCGGAACTCTTCGGCCCCGTCGGACATCCGCGCTACCGCGAATATGCACGCCACATCCGCGATAGCAGCCGCGAGCTTTTGAAATCGGCGGAAGACACGCTCGCCATCACCTGTCTCCTCGATCACGATCCGGAAGCCCGCGCGGACGCGCGCGTCGATTTCAAGGCTGCCGTTGGAGAAGCCTGGGCCTTCCACAGCGAGCCGCCGAGCCTGCACGGCCTGACGCTCGAAGCGCAAATTCCGGAGGGGCTCGAAGTTCTGATCGAGCACCGGCCGCTGAAGCAGATCCTCATCAACCTTTTCGCCGAAGCCGTTCGCCGCTCGGACGCACGCGGCACGGTCGGGCTCGTCGCCACCGTCGATGGCGACCTCGTGCAGATCGAGGTGTTTCTGAGGGGCCGTCCGGACAGCACGAGCGTCGGGCAAGCGTCGCTCCCCGTCTCGCTCGCGCACGCGCTGCTCGAACTGCAAGGCGCGACGCTGATCGAAGTCGACGATCCGCACGCAACCTGGCGGGTCGTCACCGTGCTCGAATGCGCGGCACAGAACGATTTCTTCGCGACGCCCGCGTATCAGGAAATGCGCGCGCCGGTGCAGCAGGCCTGCTGAGCAGGCCGTCACTTATTGCTTGTCTTTGTTGTTTTTCTTGCCGCGATGGGCCATCCAGTCGGCGCGTTTGCGCCAGCGCTCGGACAATTGCTTCCGCTCGTCGGCGCTCAAGCGCGCCGCCTGCACGAGGAACGTCTCGACCGTCGTCGCGCGCAGGGCCTGCTCCTTACCGGCGACATTCGCGATGGCCTGCTCCAGCGCCGCGCGGTCGAACGGTTCGGCCGCGAGGCGATCCGCCGCCTCGATCCGCGCCGTCCGGAGATCCTCCATCGCGGGGCGCATCTCGCCGTATTCCTTTTTCAACTGCTCCAGCACGTCCTTGCGCCGATCTTCAGGCAGCACGCGCGTCAGACCCATCAGCCCGAAATGCTCGCGCGCCGCATGGTGGGGTCCGTGTCCGTGCTTTTTGAAGCTCATGCCGACGAGCCCACCGACGAACAGGAGGTTCAGCGCCAGCGAGCCGATCAGAAGATATTTCATGCGCCGCGATCCAGTGCCCGGCGGCGAAGTCTCGCTCACAGGTAGTCCTCCTCGAAGAAGCTCGTTGCGTTGCTGTCGAATGCGATCTGGCCGAGATCCACATCTCCTTCGTACGCCGCGTCCGCGACCATCGGCGGGACGGCAGTGTCGAACGTGCCCGAGAGACCGGAGAACATGCCGAGCACGAGCGAGGCTGCGAGCAACGCGGCCGCGGGCCCATGCGTCCGCCCGCTCGTCGCGACACGCTTGCGCACGATCTCGGGATTCCAAACGCGGTTCGGCACCTGACGCGTGGGCGCGCCGGCCTCTGCATCGACCGCCGCCATGATCCGATCCGCCAGCATGCGGCTATCGACAGCCGGAGGCGGGGCCAGATCGAGCAGGCGATCCAGCGCCTCGGCTTCCTTGAGACGCTGCCCGGCCGCGTCATCCTCGGAAAGGAGGCGGGCAAACCGCATTCTCACAGGCGCCGGCCAGCGCGTGCGGTCGCTGCCGTAGCGCTCAAGCACCTGCTCGAACGCCGTGAGGCCGTCTCCTTCAATCCTGCCGTTCTCAGTCATCGTTCGTATCCTTGGCCCGCATCCCGAGCCGTTATTTCGGGCTTTCGCCCTTTCGTTTCCTTCACTCGCGTCACGCGTCGCTTTGCAAAAGACCTTTCCAGTCTTTCTCCAGGCTCACGCGCAATGCGCGTCTTGCCCGGGCAAGGAGCGATTCGACGGCTTCATCGGACACACCCAACACCTCGCCCACCTCGGCCTGGCTCAGGCCCTCGTGGTGGAACAGGGTCAGCGCGCGGCGTTGGCGCTCGGGGAGCGCGGCCATCGCTTCGCCCACGCGGCGGGCGAGATCCTGCTCTTCGAGGTTCGCCATCTGCGTCGGCGCCTCCTCAATCTCGGGGACCTCGTCCGTCACCACCGTGCGGCGGGACTGGCGGATCCGGTCCAGGCAGAGGTTCGACGTAACGCGCCTCAACCAGGGCCGGAGACCGTAAGGCCCCAATTCCAAGGTCTCTCCCGAGCGCCAAAGCCGGAGCAGCGCCTCCTGGGCGATGTCCTCGGCCTCTGCCTCGTCCTTCAACATGCGGCGCGCGAGGATGACGATTGCGCCCAGATGTCGATCGACCAGCGTCCGGAAGGCCTGCCGATCCTGGCGGCCCACGCGCGCCAACAGCGCACGATCCTCCGCAGCGTCAGGCCAGGGGCCCTGGCGCACGTCGCCCCGTGGCCCCCCTGGCGTCGACCCCTTCGGTCCGGTTGGCCCCGACCCCACCATCGCCTCGTCTGCTCTCATCTGTGTCTTGGGCAGCGTCAACTCTTAGCTCCCGCAGATGCTCATGTCTGCGGAACGGCCGGGCCCTTCGAATTCCGTCGCGGGCTACGTTACCAACTCGGGAAATCTTGTGGCTACCCCGGCCAGCGTCTCGGCGAGTTCGGCTTCGAGGGTTGAGAAATCAGGCGCGTCGCCTGCGCGCGCGAGCAGGGCCTTAAGGCCGCTCGGCGCCGTTGCAGGGTCAAAAGTCTCTTCAAGACAAAGCCTTAGGATTTGAGTGAGGTTGTGCAACAGGCGCGTCGCCTGCGTGAGGCGTTCAGCGTCGACGCCCGATAAGACCCCTGCCTCGGCAAGCTTGCGATAGGCCCCGAGCGTATTCTGGTCGAGCACCTCGGGATGCGCCGCCGCATGCATGAGTTGCAGATGCTGAGCAATGAATTCGAGGTCGACGAGGCCGCCACGCACCTGTTTCAGGTCCCAGATCCTGTCCGTCCCCTTATCGGCCGCGATGCGGGCGCGCATGTCCTGCACGTCCTTGGCGATGACGGCACGGTCGCGCGGCCGCACGAGCGTATCGCGGATCGCGGCCTCGACGGCGCTACGCAGCTCGGGCGGGCCCGTGATGACGCGGGCGCGCGTCAACGCCAGGTGCTCCCACGTCCATGCTTCCGTCGCCTGGTATTCGCGGAAGGTGGAGAGCTGGGCTGCGACGGGGCCTTTCTGCCCCGAAGGCCTCAGCCGCATGTCCACCTCGTAAAGCGTTCCCTCGGCGGTCGGCGCGGAGAGATGTGCGATGAGGCGTTGCGTATAGCGGGCGTAATACTGGCTCGGTGCGAGCGGCTTTTCGCCGTCGGATTGGTTGGCCGCGGGATCGAAATCGTACACGACAATGAGATCGAGGTCGGAGGATGCGGAGAGTTCGCGTCCGCCGAGCTTCCCCATCGCCACGACCACCGCGCCGCCACCCGGTATGCGCCCGTGGACGCGTTCCATTTCGCGCTCGACGTCATCGACCATCGCCGCGATCAGCCGTTCGGCAAGCACCGCATACGCGGTTCCTGCTTCGCCCGCGTTGATGGCGCCAGAGAGCACCTTCACGCCGATCAGGAAGGCCTGCTCGCTGCCGATCACACGCGCGCGATCCAACACATCCTGCGGATCGATGGCGTCTTTGAGTTCGGCTGCGATAGCCTCGTCCAGTTCCGTCGCGGTTGGAAGCGCTCTGAACGTGCGCGGATCGATGACGGCATCGAGCAAGCGACGGCGGCGAGAGAGAATGCGCGCAAGACGCGGGGCCGTGCCCATCATATCGGCCAGCAGGCGCATGAGAGGCGGATTGGCTTTCAGTAGCGAAAAGAGCTGAACGCCCGCGGGCAACGCAGCGAGGAAGCGGTCGAACGTGGTGATGGCGCGATCCGGATCGGCGGTTTCGGCGAAGGCCTGCACGAGCAGCGGCTGCACCTCCGTCAAAAGTTCACGCGCGCGGGCCGTGCGTACGGCTCCGTAGCGTCCGTGATGCCAACCGCGGACGACCGCGAGCACGTCGGAAGGGCGCGCGTAGCCCATGCGCGCCAGCGCGGCCACCGTATCTGGATCGTCCGTTTCGCCCGCAAACACCAGGTTCGCACCGGCGGCCGTGAGTTCCGGCGCGCTTTCGAACAGGCGCGCGTAATGCCCCTGCACCGGCATGAGCACGGCGCGCAGCGCTTCGGAGAATGCAGCCGTGCTCTCGTAGCCCGCGAAGCGGGCGAAAGCTTCGAGGCGCACGGGATCGTCGGGCACCACATGCGTCTGCTCGTCGGCGACCATTTGCAGGCGGTGCTCGATCTCGCGCAGATAGAGATAGGCGCCGATGATCTCGTCGGCGACGGGCTTTTCGATCCAGGCGAGGGCGACGAGCGTTGCAAGCGTATCGAGCGTGCGCCGGGTGCGGAGGTTGCGTTGCCGCCCGCCAGCGATGAGCTGCTGCGTCTGGACGAAGAACTCGATCTCGCGGATCCCGCCGGGGCCGAGCTTGATGTTATGTCCGGCAACGCCAATCCCCGCGCCAAAACCACGAAACGCATGGATCTGCCGCTTCATGGCGTGGATGTCGGCGATCGCCGCGTAATCCAGGTTCCGCCGCCAGATGAACGGCGCAAGCTCCGCGAGGAACGCTTCGCCCGCCTCGATGTCGCCCGCACACGCGCGCGCCTTAATGAGGGCCGCGCGCTCCCAGTTCTGGCCGAAGCTTTCGTAGTACTGCGCGGCGGCGTCGGTCGAGAGCGCAATTTGCGTGGCGCCCGCATCGGGACGAAGGCGCAAGTCCGTGCGAAACACATAGCCTGCGGCCGTCCGCTCGTCGATGAGGCGGACGAGATCGCGCGTGAGCCGCACGAAGAACGTCGGCGCTTCGAGGCCCGGCTTCAATCGCGCCAGCGCGCGCTCGTAAAATACGATGAGATCGATGTCGCTCGAATAGTTGAGCTCGAAGGCGCCATACTTGCCGACTGCGAGCACGATGTAGCCCGAGCCTTGCTCCGGCTCCTCCGGATCTTCGGGCAGCCAGTCGCCTTTGGCCGCGGCTTGGCGGAAGAGAAACCGAACGGCCCCGCGCAACGCGGCGTCGGCAGCTTCGGACAGCACGCGCGTCACCTGCATCACGCCCCAAACGCCGCCGAGATCGGCAAGCGCCGTCATCAGCGCGACCTCGGCCTTGTAGATGCGCAACGCCGTCATGGCTTCCGTTATTTCGGAGATCTCGGCCAGGCGGGTTGCGAGTGTCTGCGTGAGGGTCGCGAAACGCTGCTCGGGGCTGTCGCGGAGGATAGCTTCGAGGCGATCCGGATTGCGGACGATCTCGCTCTTCAAATAGGGAGACCCCGCAACGACACCTGCGATCAGCGTCCGTACAGGCTCGTGCTCGATCACGTCCACGAGGCCGGCGCGCGCCTCGCTCTTGCGCCAGTCCGCGAGCAGAGGGTGCAGGCTCGCGCCGTCCGCCGGATCCTGCGGCAGACGGCTCGCGGCATCGATGCGCGCGATCAGCGGGCCCTGGGCCGCGTGTTCTCCCGGCATCTCTTTCCCCCTCGGATTGGCGGTGCGGACCTAAACCGGACCCGACACCGCTCGTTGTCTTCTCGCCAGGGGAAGCGTTACCACAACCCGTAGGCCCGGATCATTATCCTCAAGCCGCACCGAGCCATTGTGGAGCCGCGCGACCGCCGCGACGAGACTGAGGCCGAGGCCCGTGCCGGGCTGGGTCCGGCTCTTTTCCAGACGAACGAAACGACGGAGCGCACGCTCGCGATCTTCGGCCGCGATACCGGGTCCCCTGTCGGCGACGGAGATTTCCGCTGTGTCGCCCTGGTTCGTCACGCGTACGGCCACGGCTGTGGCCGTCGCGGCATTGGACGCCCCCCGCTCCTCGGCGGCGCATGCCGCGTACCTGGCCGAATACTTGATGGCGTTGTCCACCAAGTTGGCGACCGCCTGACCGACGAGTTGCCGGTTGGCGCGGATGCTCATGCCCTCGCCGGCTTCGATCTCAAGGCCGAGGCCCGCTTCCTCTGCGACGGGCTCGTATAGTTCGGCCACGTCGCGCACAAGGCTGCCAAGATCGAAGGCTTCCGCGCTTTCCTCCACCACTCCGGCTTCGAGCCGGGCGATGAGCAGCAGCGCGTTGAAAGTCTTGATCAGCTCGTCGGCCTTCTCGATCGTGGATTCGAGCCCCTCGCGATAGGCCTCCGCGCCACGGCTGTCCCGCAAAGCCGCCTCCGCGCTGTTGCGCAGGCGGTTGAGGGGCGTTTTCAAATCGTGGGCGATGTTGTCGGAGACCTCCTTGAGGCCGCTCATGAGCTGCTCGATGCGGTCGAGCATCGCATTGAGGCTTTCGGACAGCGTGTCCAGTTCGTCGTGGCTTCCGCTCACGGGAACGCGTCGCGAGAGATCGCCGGCCATGATCGAGCTCGCCGTCGCGTTGATGACCTCGATGCGGCCCAACACCGAGCGACCGATCCAGATGCCCGCGATCAGCGCCGCCAGCGCCAGCGCACCGAAGCCCCAGAGGAACGTGCGCTTGATCCTGTCGGCGAGGGCCACCTGATCCTCGACATCGCGGCCGATCACAAGCGAAAGTCCCGATCCCGTCGCAATCGGAATGCCGACCCCCAGCCGGCTCGTGCCCGGCGCGTCCTTCGGCCGGTAGCGGAATACACGTCCGCCGCCCGGGTTCGCTGCAAGCTCCGGCGGCACCGCCGCAACGTTTCCGGCTATCTTTCCACGCGCCGGGTCCCACAACAGATAGAGACCCGCGCCTCCCACGCCGCTGCGCAGGCGAACGGTCTCGGCCACCGTCTTTGCATCAGCACCCGCCAGCGTTCGCGCCAATTCGGCCGCCTCGGCGCGTAGCTCGTCCACGACGTGATCCGTCAGCACCGTATTGGTCTGCCAGAAGAGCACGCCCACGATCAGCGCGGAGACCAAAAGAAAGCCAGCAGCGCTCATCGCCGCGAGGCGGAATGCCTGCGTGCTGATCACGCGCAGGATGAGATCAGAGGCTGCCGTCACGGACCATGTATCCCGCACCCCGCACCGTGTGCAGCAGTGGCTTGTCGAAGCCTTTGTCGATTTTCGAGCGCAGCCGCGAGACGTGCACGTCGATGACGTTGGTTTGCGGGTCGAAGTGATAGTCCCACACGTTTTCGAGAAGCATCGTGCGCGTGACCACCTGGCCCGCGTTCTTCATCAGGTATTCGAGCAGGCGGTATTCGCGCGGCTGGAGCTGGATCTGCTCGCCAGCGCGTGTCACCCTATGGGACAGGCGGTCAAGCACAAGGTCGCCCACCGCATAGCGCGTTTCCTGCTCTTCGGGAACGGCGCGCCGCCCTAGCGCTTCGATGCGCGCGAGCAGCTCGGTATAGGCATAAGGCTTCGTCAGGTAATCGTCGCCGCCAGCCCGCAGGCCCTTCACACGATCGTCGACGTCGCCAAGAGCGGAAAGAATGAGCACGGGCGTTCGGCTTCCTTCGGAGCGAAGCGTCTTGACGACCGAGAGACCATCGAGGCGCGGCAGCATGCGGTCGACGATCAGAATGTCGTACGCGCCGCCCTGCGCCATGGAGAGGCCGGTTTCGCCGTCACCGGCCGTGTCGGCGGAGTGCCCGCTTTCCTTCAGCGACTTCTGCAGGAACTGCGCCGTCTCTCGGTCGTCTTCAATCACCAGGACGCGCATCGCTCTCCTCGCTTTTTCGCCGTTCTGCCGCCGCCACCATCTTCCGCCTCAAGATGATATGGGATCGGATTTCAGGAAAGGTTAGGTCGTGAGCTCATAAATGGATGGGACATTGATGAGCCAAAACAAGCCAAGGGCCAGGAAAAGCGCGCAGCGCGATGCCTACGCATCGGGCAAGCGGTTTGACGCCGCCATTGGCTTGTCTTGGCTCACCCCGAAGGGGCGCGGTCCTTTCGCACTGCCGGTGCGTCGCAAAAGCTTGCAAACCATGGAGGTTTGCTGCGCTTTCGCTCCTGCCGGCAGCACGAAAGTTCTCGCGTCAATGCCCATCCATTTATGAGTTCACGACCTAGTCCGTCAGATACATCGAGGCGGCCCGGCCCCTCAAGTGCCGCGCCGCCTCGCTTTTCGTTTCGTCGATCCGGATCAGCCCTGTTTGAGCTGGATCGGCACGATGCGCCGCTGTTCCTGAGACTTGATGGAGAGCATCACCGCGCGGCGGCCAAGCTCCTTGGCCTTGCGAATGCCTTCCACCACGTCGTTCGGGCCGTTCACCACAGTGCCGCCGACTTCGAGGATCACGTCGCCTGCGCGAACGCCCTTCTGGGCGGCGTCGGATTCGGGGTCGACCTCGGAGACAGACACGCCTTCCTCCCCGGTCCGGATCGGGGCCAGGGTCAGACCGAGCTGCTGCAGCTCGGTCCCGGCGGTGTCGTCGGTCGGATTGCCCTGCTCAAGGCGCGCAATCTCCTCGGCGGAGCCAGGAAACGTCCCGAGCTTCACCTTGACGATCTCTTCCTTGTTGTCGCGCCAGACCTTGACGTCGACGGTCGTGTCGGGAGCGTATCCGGCGATCTTGCGGGCAAGATCACGGCTGTCGGAGATCTCATCGGTGTTGACCTGCAAAATCGCGTCCTGCGCCTTGAGACCCGAGTCGGCAGCCGGTCCGCCTGGCGTGATTTCGCTCACGAGCGCGCCCTTGGACTGCGTCAAGCCAATCGCGGCGGCCGTGTCCTCGTCCACGTTCTGGATCTTCACGCCGAGCCAGCCGCGGCTCACGGCGCCCTTCTCGCGAAGCTGATTGATCACCTCCACCGCGGTGCGCGCGGGGACCGCGAAAGCAATGCCCACGTTGCCGCCCGACGGGCTGAAGATCGCGGTGTTGACACCGATCACCTCGCCCTGAAGGTTGAAGGTGGGACCGCCCGAGTTGCCGCGGTTCACGGCGGCGTCGATCTGCAGGAAGTCATAGGGGCCGGAGCCGATGTCGCGGCCCTGCGCCGAGACGATGCCCGCCGTGACCGTACCGCCGAGACCGAACGGGTTGCCGACCGCAAGCGCCCAGTCGCCGACACGTGCGTCGTTGGTGGCGAACGAAACATGCGGGAAGGTCTTGCCCTCGGCCTTGATCTTGAGAAGCGCGAGATCGGTGCGCGCGTCGGTGCCGACGAGTTCAGCTTCGAGCTTCTCCTGATCGTCGAAGCTCACCTGGATGCGACCTGCGCCGTCGATAACGTGATTGTTGGTGACGACGTAGCCGTCCTCGGAAATGAGGAAGCCCGAGCCCTGAGCCTGTGTCGGGCGCGGCTGCGGCTGACCGCGGAACTCACGCGGCAGGTTCTTGAAGAACTCGTAGAACGGGCTGTCCTCGGGAATGTCCGGGAACGGCGAAGGCTGGCCGGGCGCGGGTGCGGCGCCGCCTCCGCGCTGCGCTGCGCGGTTCGAGCCGGTCACCGAGATCGAGACGACCGACGGCTTAACCTTTTCGATCACGTCCGCGAACGAGAGCGGCGCGCGCCCGAACGGCGTCTCGACGCCGGCATCGGCCGGCTTCAACTGCGCAACCGAGGGCGTCAGAGCAAAGCCACCGATAAGCAGAGTTGCGCAGGCCGCCATGGTCAGAGCCGTGCCGGCCCGCTGGCCAACCCGCTTCAACGACGACTTTGGCCCGTTCCTTGCTCCGGGTTGAGCGTCACCGGACTTCAGCATTCCAATTCCTCCACTGGGACGATGAGAGAGTGTTGCTCAGACAGGTAGTGGCTCCGGCCTTACGGCTGCCTTTCGGCCACGTTAAGAGTTGGTAATGCGGCGCAGGTTCTCTGTTTTTTCCGTCTTTTCGCTCTCTCTCGCGGCGGCGCTGCTCACGGCGCTCAGCCTGGCGCCGGGCAGAGCGGGCCCGCTCTGGCCGAACGCAGCGCCCGCGTCGGCGCCGGATCGGTCTCCCGTCGATCGAATCGCGGTGTTCGGAGCCGACGACCGCATCCCCCTCCCCGACGACCGGGCGGACCTCACCGCCTCCATCGGCCTCATCTACGAACCTGGCTCGCAGTCGGTGTGCACAGCCTTCTGCGTCGGGGACGATGTGGCGGCGACCGCCGGTCACTGCCTGTTCCGAACGGCCGGAGAACACGCGCCGCGGCTTCAAGGCTTCACGTTCCGCCTCGCGCCCAAAGGCGCGCGGGAGGCGGTCACACGCATTGCGGGCGCCCAACAGAGCGGTGCGCCCCAGAACGTTGCGGCCGGAACGCTCAAGCTCCGCGTCCGCCCCCCCATCGACGCTTCGTCCGACTGGGCGCTGATGCGCCTGGAGGAACCGATCTGCAAAGGCCGCTCGCTACCGCTCAGCCGCCAGCCCGCGGACAAACTCGTCGAGCTTTCCACGGCGCAGCGTGTCTACCAGGTGAGCTATCATCGGGACTTCGGAAACTGGGAGCTTGCGCTCGGACATCCGTGCGCGATCCGCCGCTCGTTCGCGGGGGCCGATTGGGAGACGATCTCGAAGGACTTCACCGACGCGCGCCACGTCATCCTTCACACGTGCGACACGGGAGAAGCGTCGTCCGGCTCGCCGATGCTGACCGATGGGCCGGCCGGGCCGGAGGTCGTGGGCATCAACGTCGGCACGTACTTGCAGTCGCGTGTGCTTACCCAGCAGGGGCAGGTCGTCCACCGCTACAAATCGAAGACGGTCGCCAACACGGCGGTGAGCGCGGAAGCGTTCCGCAGCGTTCTCGACGCGCTTCTGCGCGCGGATATCCTCGCCGCTCGCGACGAGATGCGGGCCTTGCAGCGTCTGCTTGCGTCAGAAGGTTACGCCGTGGGAGCCGAGGATGGTCGCTATGGACCGAAACTGAGCACCGCGATCCGCGCCTTCGAGCAGGCGGAGGGACGCGCCGTAACGGGCCTTGCAACCGTTGAGTTGCTCAAGAGGCTTTCGGCGCGCGATGCGGAACGGCGTGGCGCGCAGCCGTCGCCTTCCCAATCCTTGCATATCGAAACAGGAAGCGTCGGCGGGTACGACGGCCCGCGCAAGCGCCGCAAAACACGTTGAGTGAAACCTACGCCTTCCCGTCGGTCTTTTCGGCCAGCAGCGCATCGAGCTTGGCTTGCTCATCGGGCGTCAGGGCACTGCCTGCCGAGACCTCGCCCACAGGCTCATGTGCGGTCGTTTGTCCGGCGCGAAAGCTCGACCACAAAATCGCAACCGCCGCGAGGAGCGCGAGCAGCGGGATGAACCACAACAGCAGCGTCTCGACCGAGAACGGCGGCTTCAGCAGCACGAACTCGCCATAGCGCGCGACGACGAAATCCCGCACCTCGGTGTCGGTATCGCCCGCGACCAGGCGCTCGCGAACCAGGAGCCGCAAGTCGCGCGCAAGCGGCGCGTCGGAATCGTCGATGGACTGGTTCTGACACACGAGGCAGCGAAGCTCGGCCGAAAGTCCGCGCGCGCGCTTCTCAAGCGCCGCATCGGACAGGATTTCGTCGGGCTGAAGCGCCAGCGCATCTCCGCCCCACGAGACGGCCGCAAAAAGAACGGCAACCCCCAGCACGACGCTCGCAGCGAACCTCATCGTCGTCTCCTCACTCCGCTGGGACGCCGGCAGGCGGTGTCGTGCGCGCGGCCCGCTGCGGCGCGCCGATCCGGAGCCGCCGGTCGCTGAGCGAGACCGCGCCGCCGATGAACATAATGAAGCAGCCGATCCAGATGAAGCGGACCAGGGGGTGGAAGTAGAGACGCACGGTAAACGCGCCATCCGGTTGCTGGTCGCCGATCACCGCGTAGAGATCGCCACGCCAGGAGGCGTGGATGCCGGCTTCCGATGTCGGCTGCGGCGGCGCATTGTAAAGCCGCTTCGAGGGCATAAGCTGCGTGATCGCGCTTCCCCCCCGCGTCACGTCGAACACGCCGATCGTTTCCGTGTAGTTCGGACCGCGCGACGGCGCCGCGCCGCGGAACGTCAATTCGTAGCCGGCGATTTCGCTCGTCGTGTTCGGACGCATCAGCAGGATCTGCTCGCTCTTATAGGCGCTCGTCCCGACAATGCCGCACACCATCAGGCCGACGCCGAAATGGGCCAGCATGGTGCCGATGGCTGCGCGCGGAAGGCCCCTGAAGCGCCGCCAAGAGTCGGCGACCGGCGCGGAGCCCAGCTTGATGCGATAGGCGATCTCTGACACCGCGCCCGCCATCACCCACACGCCGATGGCAAGGCAGAACGGCGCGATCCACGGTCCCCGCTCCGTCAGAGCGAACGTCGCGACGATCACCAGGATGGAAAGGACACCCGCCGCCAGAAGCCGCTCGGAGGCGGCCGCGAGATCCGCCCGCTTCCACGCAAGCAGCGGCCCAAGCGGGACAGCAAGCAGCAGCGGGATCATCAACGGCACGAACGTCATGTTGAAGAACGGCGCACCGACGGAAATCTTGGTGCCGGTCAGGGATTCGAGCGCCAGCGGATAGAGCGTGCCGACGAGAACCGTCACGCACCCCGTCGTCAGCAACACGTTGTTGAGCACGAGAGCGCCCTCGCGCGAGATCGGCGAAAACACGCCGCCCTGCTGCAGGTCTCGCGCACGCCAGGCGAACAGCGCAAGACCGCCGCCCGTAAAGAACGCCAGAATGCCGAGCACGAACACACCGCGGTCGGGATCGACCGCGAACGCATGCACGGAGGTCAACACGCCCGAGCGCACAAGGAACGTGCCCATCAGCGACAGCGAGAATGCAAGGATGGCAAGCAGGATGGTCCAGACCTTCAGCGCCTCGCGTTTCTCCATCACGATCGCGGAGTGCAGAAGCGCGGTGCCGACCAGCCAGGGCATGAACGACGCATTCTCTACGGGATCCCAGAACCACCAGCCGCCCCAGCCGAGCTCATAGTACGCCCACCACGAACCGAGCGCGATGCCGACCGTGAGACACATCCAGGCGCCCAGCGTCCAGGGGCGTACCCAGCGCGCCCACGCCGCATCCGTGCGTCCCTCGATCAGGGCGGCGATTGCAAATGAAAACGCAATCGAGAAGCCGACGTAGCCCATGTAAAGAAACGGCGGATGGATGGCGAGCGCCGGGTCCTGCAGGATCGGGTTGAGGCCGCGTCCGTCGAGCGGCGCGGGATCGAGCCTCTCGAACGGGTTCGACGTCAGCAGCATGAAGAGCAGGAACGCCACCGCGATCGAGCCCTGCACGGCGAGCACGTTGGCCTTCAGGGTCGCGGGCAGGTTGTTGCCGTAGGCCGCGACGGCCCAGCCGAAGAGCGCGAGGATCAGCACCCACAGCAGGAGCGAGCCCTCGTGGTTCCCCCACACGCCCGAGATGCGATAGATCAGCGGCTTGGTCGAATGAGAGTTCGCCACCACGTTGGCGACGGAGAAGTCGGACGTGACGTAGGCGTACGTCAGCGCCAGAAAAGAGAGAAGGATAAGCACAACTTGGGCCGACGCTGCGGTGTCCCCGAATGCCATGAGCGCCGCATCGCGTTTTTGCGCACCCCAGGCCGGAATGATCGTCTGCGCGGCCGCGACCAGCAGAGCAAGGATCAGCGCAAAATGTCCGATTTCGACGATCACATCATCCTCGCCCGCAGCGGCGTGACAAAGCCGCCCGCTGCTCTCTCGCGTTTTTCTATTGCGTCTCGGTGCCGCCGTACGTGTTGCCGCCGCTTCCGTAGCTGCTCGTCCCTTCGGTCCCGCCCGGGTGGGTGGCGCCCGGTCCGAGCTTGACGCCCCGCTCTTCGAGCGCCTTGGCCACTTCCGGCGGCATGTAATTTTCGTCGTGCTTTGCAAGCACGGTGTCGGCGACGAAGTGGCCGTCATCCCCGAGCGTGCCTTCGGCAACGACGCCCTGTCCTTCGCGGAACAGGTCCGGCAGAATGCCCTCGTAGCTCACCGGCACGGATTTCAACGTATCGGTCACGGCAAAGCGTACGAACGTGCCCTCACCGCGCGCGACCGAGCCGTTCTCTACAAGACCGCCGAGACGAAAGCGCGTGCCAGCCTCGATCTTCTTCTCAGCGATGTCGCTCGGCGTGTGGAAGAACACGATCGATTGTCGGAACGCGAACATCATCAGGACGGCTGCAAGCGACAGCACGCCCACGCCCAGGCCGATCAACAGTCCCCGTCGTTGCTTTCGGGTCATGGCGTGGTCCGATCCTCCTTGGCGCCGAGGCCGAGGGCGGTTTCGGCCCCCGCAATTCTGCCCAACGCCTCTTGGTCGCCCGCGAACGCGCCGCGCGCCTTGACGATGGCCAAGCGCGCGTCATCGTCGCGGCCCAGAACCTTATAGGCCCGCGCGAGCCGCAGCCATCCCTCGATATCCTGTGGGGTTTCTTCGAGGCGGGCCGCAAGCCGCGCCACCATGTCACCCACAAACGCGTCCTGCTCTTCGCGCGACATCGAGGAAACGTCGGCCGGATTGACGCTGACTTCGCCCTCGTTTGGCGCGGCCGATTGCGGCCCATCGGCCGTACCCGGCGCTGGCTGGGCTTCGACTTTCTCTCCCCTCAGGCGCGCCTCGACCAGCAAGAGGCGCTCGGCCACGGCATCCCGCCAGGGTGCGTCGTCGGGCGCGCCCGACAACAGCGTCCGATAATCCGCAACCGCGCCTGCCAAATCCCCGTCCTGCTCGCGCGCGAGTGCCAGCCAGACCCGCGGCTGGACATGCGTCGCATCGAGCTGAAGGAGCCGAAGTGCCGCGGTGCGGACAGGCTCGGTGACGACGCCGCTTTCAGCCAGCAGCGTCGCTTCGGCGAAGCCCAGCAAGCGCCGGTCGGATTCGCCTTGGAGGCGGTTCGCTTCCGCATACGCGTGAGCGGCTTCGGGATAGCGGCCGATCCTGAGATAGATCGGCGCGATCACGTCCCATCCCTGTCCGTCTTCCGGATGCTCTCGCAAACGTTCCTCGACGCGCTGGATGAGGCCAGCAATCGCGATCTCGCTGCCGGGCCCCGTATCGCGCGCCGCGAACGGCTGAGCGGGCAAGTGTGGCGAGCCCATGCCCAGATAGAGCACGATCCCAAGCAGAGGCACCAGGGCAGCCATGCTCGCGTAGATCCTGCGCGCAAACTTGGAATTCTCACCGGCCCGTTCCGCCTCGGCGGCGACGCTCTCAGCCTTCCCCGCGCGCTTGATCAAGCGGCGGGCAATTTCGGCGCGTGCGCTGGCATGTTCGTTCGCCGGGATGAGGCCGCGCTCGCGCTCCGCGTCGAGTTCCTTGAGCTGGTCGCGATAGACGGCGACGTCGGCTGCTTCGGACGCGATAGCCGCAGGCCCTTGAGCCTGCCTCAGCGGCCGTAACAGGTACGCGACGACGGCCGCCGTCAAAATCGCGAACGAGACCCAAAGAAGCATCGGGAACCTTAGAAGACTTCTATTTCTCCGGGTTCAATAGGCGTGGGGGGCCGCACTGACAAGGGGCGCGATGCCAATTGAGCTGCGTTTCGCGCGCTCGTGACGATCTTTTCCGTCGCACCCCACAAAAAAGAGCCGGGCCTCCCGCATTGCAGCGGAAGGCCCGGCTCGATTTCAACCCATCGGATGGTCGTGCGGCGTGGCGTCAGGCGACGTTGCTCCACGTGCCGTCAGGATTGCGGCAGGCCGTGCCGCGCATCGACTGCGGGCGACCATCGATGTAGATCTTGTGGGTGTAGTCGCGGCAATCGATCTGGCCGCGCTTATAGGGCCGGCTCGGCACGACTTCACCGTAGCGTCCGTTGTCGGGGTTGCGCCACTGGCGGGAAACACCCGACTGGCCGCGCTCAAGCGCATCGAACTCGGCTTCCTGCGCGAGACGGCGATCCTGCTCGTCCATGGAGCGGCCGATCTCGCTGCCGACGATGCCGCCGACCACAGCGCCAATGGCGGTCGCCGCGATGTTGCCGCCGCCCTTGCCGACCTGATTGCCGAGGATGCCGCCCGCGACCGCGCCGACGACCATGCCCGTATCGGCCTTGCTCGGCCCTTCAGGCCCGCAGCCTGCGAGACCGATCGAAACGATGAGAAGCGCGGAAGCGCAAAGCGTGCGCATGAAGATCCCCGTTTTCTTGCAGAATTCTTTTTGCCGAATTCTCTTCTCGACGAATTCTCTTCTCGACGAATTCTGGCCGAGTTCACATTCCCGCCCGGCGCCTCGCCGAAGTCGGAACCACAGCCTGAGGCGCGCCGGACATCTTCCCCAATGCCCAGGCATTGCCGGAATGTGACTCGTCTTCAAGCACATCCATAACCCCGTTTCTACCGGGATTCAGGCGAAAATTCGACGTTGCGCACTGGAAATATGGGCTTTTGCTCAGGCAGAGGGAAGCTCCATGCGAACAAGTAGGCCACCCATTGTGGATGGCGCGAGCTTGAGGGTGCCCCGGTAGGACTGGACAAGGTCCGTCACGATGGAGAGGCCAAGCCCAGAGCCCGGCTTTGTCTCGTCGAGCCGCACTCCCCTCTTGCCGATCCGGGCGCGCTCTTCGTCCGACAACCCCGGCCCATCATCCTCGACCGTGATCTCCACCCGGCCGGGGATGCGCCGATTGTCCGCCGCCACGCGGACCTTCACTTCGCTCTCGGCCCATTTGCAGGCGTTGTCGCAGACGTTGCCGAGAATTTCCTCCAGGTCCTGACGTTCCCCGGCGAAACGGACGTGCGGCGGACAGGCGATCTCGATGTCGATCGCCCTGTCGCGGTGGATGCGTTCCAGCGCTCTCTTCAACGGTTCCAGCACGTCCAGCACCGGCGTCGCGCGTCCGATCACGCGAACCTGTGCCGCCATCCGCGCGCGGTCGAGATAGTGGTTAACCTGATCACGCATGATCTCCGCCTGCTCGGCGATCTTGTCCCCGAGCGGGCCTTTGTCCTCGCGTGCCTCATTGGTGATGACCGCCAGCGGCGTCTTCAACGCGTGGGCCAGATTTCCGACCTGGGTTCGCGCGCGGTCGACGATTTCCTGGTTCGATGCGATCAGAGCATTGAGCTCGACCTGCAATGGCTCGATCTCGGCGGGGAGTTCGCCGTCGAGCTTGCCTGCCGCGCCCGAGCGGATTTCTGCCAGCCCCTGCTCGATGCGCTGCAACGGCAAAAGGCCAAAACGCACCTGAAACAGCGTCACCGTCACGAGACCGATGCCCGTCAGCGCGAGCGCTACGGCAAGGCGCGTTAGAAAGTTCGCGACACGGCTCTCAAGCCAGTCGATGGGCCCAGCCACCAGCACCGAATAGCGCGGCCCCTCGCGATGATAGTACGGCGTGTCGATCACCTCGACCATGCGCAGTTGCTCGCCCATGGGCCCCGTGGAGTTCATCCAGCGTGCGCCATTGGCGTCGGGCTTGATGTTGTGGCGAAACGGAATGTCGATCTCGGCGCCATCGAGAGACGCCGAGCCGAGACGCGGTGCCGTGGCATCGTCGATGGGTTGAATCTGCCAGTACCAGCCGGAGTGAATATCCTCGAACAGCGGCTCGTAGCGGTTGTTCGGCGCGATGGGCGTCGCGGCACCCACCATGCTATCGACGGCGATGGCATAGACGAGCTTTTCGAGGCGGGCATCGAACGTCGCCTGCACGTCGTCGCGGTACAGCTCGTAGATGATGAGGCCCGCGATCGGCAGCACCAGAAGCGTCCATGCCGCTGACGTCGCAAACAGCCGGAACGCGAGGGACTTAAGCTTCATCGGCTCCACGGCTCATGCGGTAGCCGAGGCCCCGCACCGTCTCGATCACATCGGCGGGCAGTTTCTTCCTCAGCCGCCCGATAAACACCTCGATGGTATTGCTGTCGCGGTCGAAATCCTGCTCGTAGAGATGCTCGACGAGTTCGGTGCGCGAGACGACGCGCCCGCCGTGATGCATCAGATAAGCCAAAAGGCGGTATTCGTGAGACGTCAGCTTCACCTGCTGGCCGTCGCAGGTCACGCGCGCGGTCTTGGTGTCGAGGCGCACAGGGCCACACTCGATCTCGCTCTTGGCGTGACCCGAGGCGCGGCGCACTTGCGCGCGGACGCGCGCAAGCAATTCCTCCATGTGGAAAGGCTTGGCGAGATAGTCGTCCGCACCCGCATCCATGCCGGACACCTTGTCGCTCCAGCGGTCACGGGCCGTCAGGATGATCACCGGCATGTTGCGGCTCGCGCGCCGCCATTGTTCCAGGATCGAGATCCCGTCCATCTTGGGCAGACCCAAGTCCAGAATGACGACGTCGTACGGTTCGGTATCGCCGAGGAAGTAACCTTCCTCGCCGTCGAACGCCTGATCGACGGCATAGCCCGCCCCCGTCAGCGCAGCATTGAGCTGGCGGTTCAGATCCTTGTCGTCTTCCACGACCAGTATGCGCACGTGACGTCTCTCGCAGTTGGTTAAGCCCTGGTTGGCCCCGACGACTATAGTCGGCCGTACGAGCCGAGCCTAGTGCCAGGCTCACTCACGCCAACGGCCGACGGGCGCATGTCCGTCGGCCGTTGGCGTTCGAGCGGGACGTATCGCCCTCCTGGGCGCTACTCTTTCCCCTTGAATAAGGCACGCGCGATGGGCTGGCTCGCGCGCATCCGGCCGAAGATCGTGAGCAAGGTGCCGATCAGTGCGCCCACGGCTTGTATCGCCTCCACGGATTGCTCGCCCGCATCGCGCACCTCGTCGCCCGAAATGTCGATGCCGGTCACCGGCGCCATCGCGGGCACGACGACCGAAAGCATGGTGACGATCGTGCCCCAGATGGTGATGGAATGGCCCCACCATTTGCCGTTGCCGGATGTGGTCGGTGTCTTGCTCATCTCGTTTTCTCCTTCACGCTTGTCGGATGGTTCGCGTTGGGTCTCGGCCTCGATGGCGCGCGCGAGCTTGAGCGTCGCGTTGACGCGCCTGAGCCAGCCGCGGCCGAAGCGGGGAAAGTGGGGAAGCGCGCGATAGCGCCGCTCGCGAATGGCGGCGTAAGCGGCGAGCGCATCGGCCAACGGCATCCGCGAGATGGCCGCGCGCGTGAGCGGCCCGATCTTTCCGTCGACCGTGGTGCCGACGGCTTCCTGCAGAATGCGGATTGCCGTAACCGGTCCGTGATTCACGGCGGCATCGAAATGCATGAGCGCGAGCGGCGCGGGCATTTCCGCGCATCTCGCGACGTCCCAATACCGCCGCCGGTAAATTTCACGCACCGTCGCGTCGTCGATCCGCTTGAGATCGCGGACCATGCGCGCGCGATTTGCAGCGCTCAGCCTAACCTTGCGCCAGAGCGCGAACACGGCCAGCGTGATGCCCTTGTTGGTCGGCCCGCCGGGATCATGGGGATCGTCTGTGTATCCACCCTCCATCTTGAGCACGTGGGCGAGCGCCCGCTCGAACAGGGTCTCATCCTGCTGCGTTTCAGCCCGCATTTCCGGCCAACGCAAATCCAGGAGGCGGCTTTTCGGATAGCGCGCGACCGAAACGGCGTTGCCCTGATTGCCTCCAAGCAGCACCACGTGCTCGTCCGTTTCGCCGAGCCAGAACCCCACGTGACCCAGCGCCGGATTGCGTCCGCGCGAAAATACTGCGACGGCCCCCATGCGCGGCTCCGAGAGCCGCTGGCCCCACGAGAGGTACGACCGCGCCATCAGCGAACGCGTCGAGCGAGTGCCTGCCCGTTCCAGGCACGCACCCAAGTACGCCGCGCACCACGCCACCTCGTCACGCGTCACCTTCGGATGACCCGCGTCGCGGAACAGCGAAACAATGCGCGGGTTCGCGCGCGCACCTGCCTGCTCGGCTTGGCCGAACTCGCGCCAGGCTTCTTTCAGCCAGCGTGCGTCATCCATGTACGATCCTCGATTTTTGCTCAGGCGCCTGTTCGCGCGCGCCCGCTCAGACGACTGCGAACTTCGCGCTCCCGCGTCCGTAGGCGCTGCTCATCTGGTAGACGGCCACGCTCACCGTCGCTTGCGGACTTCCGAAGTCGTCCACCTGCTGGGCGGCTGCGTAGACACAATCAGGCGTCGCCGTTGCGATGGTGCGCTTGACCGTATCGCCATCGAGGATGTCCACCTCGTAGGCTTCCGCGTCCTCCGCCAGCGGCACCTCGGCCGTATCCCAGCCGTCGCCCCCCACGCGGGTCCTGCGGATCCAGCCCAACGAGAGATCGTTGTTTGCGGCTCGCACTCCCCGCACGTGAACCGGAGACAGGGGCTTCAGCCCACGCCCCGCAAACGCGTGCGTCGCGCCTGCGTACGAGCGGTCGGCGATGTCGCGATTGGCGGGCCCGTACCGCCAAAAGAGCGGCAACCCGATCTCGCCCGCCGCCACGCTCACGCGCGCGATACCGGCAAGCAGGACGAACGTCGCGCCTTCGGGAAGCTGTGAGCGTCGTTCGAGCTCCGTCCCGCCTTGCCCCCTGAGCAGGTTCGACAGCTCGTAGATGCCGGTCCCCACCAGCGTTGCGTTCTCGAACTGGATGACCTCCCAGCCGCCCGCCTCGTTCTTCATCGCTGCAGCATTTGCGCCGGCAAGGAGCTGTAACCGCGTCACCGAGGCGAGATCGCCTCCCGTGATCGCGATGCGCAGGCGTGTTGCCTTATCGATGACCCCGAGCGGCCCCGGCAATAGCGGATCGAGTGTCACGCCCATCACGGCAGGCGCCGATGCTACCGCGCGGAGCACGTAGCCTGCATCCTCGGGCGAACTCAGGACGGCCACGCTTCCCGGCCACGGAAGCTGGAAGGCGGCGACATAACCGTCTTCCGGCCGTTCATCGCCGCGCAAGAGCGGAAGATCGAGAAATTCGACGTGCGGCATGCCGTCGAAGACGACACCTTCCACCACGGTCTCCCGGTCGCGCGGCATCCCTCCCCGATAAATATCGGGATCGATGCTCAACCCTTCGATCTCGCGCAGACCCCGCTCGCCGATTTCGGTCACGCGCACGAGATAGCCAACCCCGTCCGTCTCGACGGAAACGACGTCACCCGGCTCGACTCCCAGCGCGCTCGGCGGCAGCTTGAACGCTGCTCTCTCGCGTGCGGCCCACGTTTCGAACAGCCACGCATCGGCAATGCGTGACGCGCTTTCGTGCTCCAAGACAATCGGCAACTCGGCCCGCGCCACGCGGCCGCTCGTGCCGGTCAGGCGTCGCGCCTCAGCCACGGCTTGCCGGTAGTCTCCGGAAGCCACGATGTGGCTAAGCTTTGCGGAAGCGGGCAGATCGGTTTCCTGTGCGCGCGTCATCGTCAGCAGCGCATCGCCCGGACGCTCCTCCACCAGATCCTCTTCGCCGAGCGTCAGAACCGGCGGCTCAGCGCCGCGATGACGAAAGCGGATCAGCCCTTCGCTCTCGAAGCTGTCGAAGAAGTATGCAAGCTCCAGCGGCTGCAGCGCGTCGCGCGGCGACATCAGCCGATCGATCACATAGCCGGGCACGATCCCGGCAAGCCTGCTTGCGTCGTGATTTTCGAACCCGTAGTCGGCAAGGATTGCGTCCACCATCTCCGCCAGCGCACCGACCGAGAAGCGCCCGTTGAGCCAGTGGCCGAAATGCCAGTTCTCGCCGTCGCTCCAGACGTCGAGGTTGTAGGGGAACACCGGATAGGGCCGCGCATCCCAGCAATAGACATGAATGCGCGCAAGATCGACCATCCGCCCGCCATACACGGACGATACCGGGTTCCGTCCCGCCACATATGTCTCGCTCGCGGGATCGAACGTTTCGATCAGCGCCTTCAGGTAGCGGCGCTGAATGAGATCGTCGCGCGTGCCCCGCGAGAAATAGGGAAAGAAGCTCTCGCTCGATTTCGGATCGACGAATACGTTCGGCTGGTTTGCCCCCTTGTCGATCGCGGGACAGCCGATCTCCATCAGCCAGAACGGTTTCGACTGAGGCACCCATGCCGTGGGCGTTCCACTCGGCGTTCCGCCCGGGCGATTGAAATGCGGGTTCTGCCACCACGAGCGGATGTCCTTGTAGCGGAACACCCACGGGCTACCGTGACCGTCGCTGATCGGAGAGCGGATCTGCGCCTCGCGATCGGCCGCGCTCGCATAATACCAATCGAAACCCTCACCGCCTGCGACGTTCGACCTCAAATACTCTTCGTCGTAGATCGTGCGCGCGCCCGCGAGATAATCCACGTGACTGGTCCCGTCGCGCCAATCGGCCAGCGGCCAATAGCAATCGATGCCGATCGCGTCGATATGGGGCGAGGCCCAAAGCGGGTCGAGATGGAAGTAGACATCGCCCGATCCATCGGCAGGCTGGTGACCGAAATACTCGGACCAATCGGCGGCATACGTCACCTTTGTGCCGCTACCCAAGACGCTCTTTACATCCGCTGCGAGAGCGGCGAGCGCGGCCACGAACGGATAGCTTGCCGCATCCGAACGCACCTGCGTCAGCCCGCGCATTTCCGTGCCGATCAGGAACGCGTCGACACCGCCCGCCGCTTTTGCGAGATGCGCGTAGTGCAGGATCATGCGGCGGTAGGACCACTCGTTCGGCCCGGTGTAGACCACACCGCTTCCGGACACGGCGAAATCCGACACAGCCGCCGTGCCCACGAACGCGGCCACCTGGCTTGCAGCGCCCGATGCCTTGTCGGGGCTCCCGCTTGCGCCGGGTGCCGGATCACACGTGATGCGCCCGCGCCACGGATACGCCGCCTGCCCGATACCGCCGTAAGGATTGGGCAAGGCGTTACCGCCTGGAACGTCCATCAGAATGAACGGCGTCAGCACGACGCTTTTGCCGCGGGCCTTCAGATCTACAATCGACTGGACGACAGCCGCATCGGCCGGGGTCCCACCGTACGCCGGCCTCCCGTCCTTCGTGCTCACAAGATGCGCCGTCGCACGCGTCAGGCCCGCCGCGCTCCACGTCATCGGCGTCGTCGTCTTCTGGCTGACCTCGACGCCCGGCTTCATCTCGCAGTCACCAGCTCTCAAGTCGGTTCCGAACCAACTCACGATCAGCGAGATCGAATTCGCATTCGGCAGCGTCGCCTCCAACTGATCGATCCCGACGCTCCAGTCGGTTCCGCCTTGGCGCGTATGCACGTTCTCGGATTGCGAAACACCGCGCGCAAGCCTCTTGCTGACAGGGGTCGTCGCGTAAATGAACTCGCCCGATCCCGGAATCACGCACACGCCCCGGATTTCATCCCCGAACGGTTCGACCGCGCGATGAACCTCGAACGAAAGCTGCGGAATGCGATTGCCATAGTCGCCGAGCGGCATGTCCTCGAACACCACATAGGCGACCCCCCGATAGGCCGGGGCGGCATTCGCGCCCATCAGCGCCGCGATCAAAGTGTCTTGCGCCTGGGTGTCGCTGCCCTGGTGCACGCGATACTTGATCAGCGCGAGGTCCAGCTCTCCTCCGTCCGCCCATACGCGGCCGATGCCGTTGATTTGGCCTTCGGCCAGCGCCACCGCAAAGCTCGCCGTGTAGCGATACTCGGTGCTTTCCGTCACGGACCCTTTCGATTGTCCCCCGCCCTTTCCGCTCCCGCCGCCTGTCCGCGTCGTGACGATGTGCTCGCGGATCTGGTCGGCCCAGATCAACTGACCGCCAAGACGCGCGCGGCCGTAGAGGCGCGGGATCGGCGCGCCTTCCGTGGAGGACGTGATGTGGAGATCGTTGAGACGCGGGCCTTCCACCGTGCGGCGCTGACCCGACGGGCCGAACAGCGCATTGTCGATGTACGATCCCGCGAAGGCCCCGATCTGGCTTCCGATTGCTGCGCCCGAAAGCGTCATTCCCAGCATCGAAACGCCGGCGGGCAGGATCGCGCTTCCGGCGGCGGCGCCGACGGCTGCAAGGGCTAGCGTGGCCATGATCGAACGGTCCCTGGAAATGCGAAACTCGCCGCCAGGCGGCGGCGCCACCACGGGCTGAACGGCACCTCAGCCGCGCGGCAATGCTCCATCGCGTGGATCATCGTATCGGCCGTCGCGCGCAAGGCTGCGTGCTTCGCGATCGCGCCCGGCTTCATGCGGAAGATCAAAACGTCACCGATCTCCGGCTCGCCCTCTCTGCGGGGCACGAGGTGGCGCAGCGCGGCCTCGATGAGCGTCTCCTTCCCGCTCGCCTCGCCCCAGTCGCGCGAATAGCCGGGCGGCGTCTCCGCATCCTCGCCGTAGATCTCGCGCCATACGCCCCGGATTAGGCCGAGGCAGTCGGCCCCTACGCCGACGACGCTCGCCTGATGATGATACGGCGTCCCGATCCACCGGCGCGCTGCCACAACGATTTCGTCGCCACCGTGCGCGCGGTAGCGGGCTCTTTGCTCTTTCACGATCACCTGCCTCTCAGCGCGACGTGGCCCCCGGCCTGCGGACAGCGGTGAGGAAATCGTTGCCGGGCATGTGCGGAAATCCGCGAAAGTTGACGGCATTCGCGAATTTCGCGCGGCACGTCGTAAGACGCTTGTCGCAGCCCGCGCTCACCGTAAACGTCTGTCCTGGTGCGAGCGGCAGGCGCGCCTGGCTCCACAGCTCGACCGTCACCACTCCGCCCGCGTGCGTATGGCTCTTCACCTCGACCTTCTGGCCTTCCGCCGCACCGGACGTGAAGCTCAAAAGCCCGTGCGTGAACCAACCGCTGGCGAATGCGGCGAGCCCGCTTGCCGTGAACCGTCTTGGACTGTCGATATTCTGAAGTGCGCCGCTCCCGGTGAATTCCCCATTGGCGAGGGCAACGCGGCAGCGCGCATCTCCGAGATCGGCATCGCAGGCGTACTGAAAAATGCGCCCTTTCGTTTGCTGAAGAAGGTGAGCGAGCCCTCTGACTTCGGCCGCGAAAGCCTTTCCGCTGCGTTTCACCTCACCGAGATTTCCCCTGCGCATGAGCACCCGCTCGGCGGGCGTCATCCAGTTCACACGATAGATTTCCACTTCGGCATTGTCGTAGATTCCGGCCGCGAGATCGCCCTCGGCAAGGCGCTCCGACGTCATGGCGCTGGTCACTTCCAGGTTGTCCACTCCGAGACCCACCGCATCGCGGATCTCGCTCGCGCCCATGCCGGCCGCGGCCTCGTACACCGTTCCGCCGAACGCCACGTCGCGGTCGTGATCGGTGAACCCCATGACGACGCCATCGCGGCGCGCAAGCCGCCAGCACCAGCACAGCGTCGTCGCGCCGGAGGTGAGATGTGCCTCAAGTCCGCTCGGAAGCTGCTTCATAGGCGGATCTCGACGATGGGAATGCGCGGGATCGCCCCGCTCTGGAACCCCGACAAATTGATCTCCAGCTTGTCGGTATCGAACCGCACCGGCACATCGAACTCGAAACCCGCCGTTACGACGGTATCCGCTGCGGGCGTTTCTTCCTCGCCGAACAGGACCATCCCCGTGGCGGCATCGACGCTGAAATGCGTGCCCTCTATTCGCACAGCGCCGTTCACCGCGACTTTCACGCTGCCGGCGACCGGCTTTGCGATATCACGGACGAATGGGGCATGGAGCGCACCGTACGTCTTGCGGAGTTGAAACGCTCGGGCCGAGCTGTCCCCCTCGCCAATCACCTGATCGAACGCAGTCGTCTGCGCGCCTGGCGCGCCAGACTTCCAGTCCGTGTGGTCGCGCCATCGGAACCCATGGAACCTTCCGCGCCGCTCCTCGAAAAACGCAATCACCTCATGCAACGCATCGAGCGAACGCACGCCGTAGCCGGCATCGTAGCTCCGGCGCGACGCGAGCCAGCGGGTGTTGCGCTCTTCGAAGCCCGACCCGAGCACCACGACATCGGTTCGCCGCTCGGGGCCGCCTTGGGCACCCCGCGAAATTCCGGTCGGAAAGCGGATTTCGTGAAAGCTCACGCGCTCTCTCCTCTCGTCGACTCAAAGATTGCGTTGTCCAAACGAGACGGCCCGCGCCAGCATGGCGGCAACCTGCGCCTCCGAGCGCACAAAGCTCTCAGCGTCGGCCGTGTTGACGTTGAACGTCACCGCGACACCCGCGCCGCCGCGTGCCGCAACACCCAGACGACCGTCCGGGCCGCGCGACAGCGGCATGATCGCCTCCGCTCCGCGCTCGCCCGCGATGCCGAAACGTCCACCGGCAAGCGGAAACGATATGGGGCTTTGGATGACGCCGCCGGACGCGAACGGGACAGGTAGGCCCTGCCGGATCGCGCCGCCTTTCGCGAACGCAACACCGCCGGACATCAACCCCGACACCAGATTGCCAAATCCTTGCTCCAGCGGCCGAAGCGCGGCTTTGAGAACGATGTCCGAAAGCCGGAGCGCGAGCGTCCGCAACACGTCTCCCACCGCACGCCCTTTGACGGCGATGCCGTCGAACGCACCGGCGAGCACGGTCGAGAACTGGCGGCCGAGGCGCGCTGCGTTGCGAAGTTCCGACGAGAGACCCGTCGTGTCGGCATTGATCGCGACCGTCCACGTTTCAGCCGGCGTATTAAATTCATTCATGGGAGCGCCTCATTCTGGTCCGTCGGGATAGCGGTCTTGAAGGTCCGAAAGGTCGCTTCGCGACGGTGGCTCCTCAGCCCGCGTGGCGCCGAAGCGGCCACGCACCGCCGCGTCGAGTTCCGCAAGCGTCAGGCTCCAGAAGGCGCGCGGTTCGAGGCCGAGTACGCCAAAGCCCACGGCCATTACGTCCTGCCAGGGAAAGGGCCGGCGGCCTCGCCTCCCTCGCAATCCGATCCGTCGCCGCCAGACCTCGCGGAGAACGTCGTCGCCAGCAAACGCGCCACGATGTCGACGTATCCCGCCGCCCCGCCTTCGACGCGCATCGCCGACACCGCAAGATCGCTCACGTCGAAGCCCGCCCCGCGAAGCCCAGCCCCGATAATACGCTGGCAATCGCGCGCGGAAATGCGCCCCGCTTCGAAGCGCGTTGCGAGCGCGAGCATGTCCTCGTCGCCGAAAGCGGATTCGAGTTCCGCCAGCGCACCGAGCGTCAGACAGAGCCGATAGGGCTTGCCGTCGAGCACGGCGTCGATTTCGCCCCGATGGCGGTTGGCCATGTCGTCATCCTCCCGATCAGTCTGCGTCGAAACTCAGCGCGCCCGCGGATTCGAGCGCGATCTCGAACGCCACTTCTCCGTCGTGCCGCCCAGTGAGCTCGAACGAGGTAATCTGAAACGCGCCCTCCACGACGCCGAAATCCGGCACAACGACCTGCCAGTCGCGGATCGTTCCATCGAACACGTAGCTCCTGATCAGCGCGTCCGATTCCTCATCCTTGAAGATGCCCGATCCCGAAAGCCGCGCGCTCTTGACGCCCGCCCCCGCCAGAAGCTCGCGCCACTGTCCCGCACTCTCCTGATGCGTCACGTCCACCGTCTCGGCATTGAACGCGATGGCTCTCGCCCGCAATCCTGCGACCGTCGTGAAACTTCCCGAGCCGTTGCTGTCGACCTTCAAGAGAAGGTCCTTGCCTTTCTGCGCCGCCATGTCATCTCCGATGCTCTTGCTAAGGGTTCGGCTCGGTCACGGCGCGAAATCGCGCGATGCCCTGCCATGTCTCGCCGTCTCTCTCGCGCACGGTATCGCTCGCCTCGTGGCGGATGCTCACAAGCCGTTGTCCCGAGACCGACAACGCAGCCTCGTGCAGGGCGGCGCGAAGCGCGTCGAGCACAAGATGCACTTCGCGCGCGCCGGGAGCTTTCGACCAGGCCATCAGCGTCAGCGCATGCTCCGCACCTTCCTCCGTGCCGGTGCTCCAATCGCGCGTCGTGGTCGGACCGAGCGTGACATACGGGAACGCAGCACCGCGCGGCACCTCGTCGTAAATCCGTGCGCCACCGAGCGCCGCAACGAGGTCCGCATTCGCCACGAGCGCGCCGTACACCGCCTTCTGAAGTTCCCACGCTGCGCTCGACATCCATTACCTCATTGCCTCGTCATCGCCCCGCTCGACGCGCGGTTGCGTCTCTCGCGGCCTTGTGCCGGCTTCGGTTCGCGTGGCGCGCAGGACCTCAGCCCGCGCCATGGCGCGCCGCCGCACAGCCGCAACCAACGCCTCGATGCGTTGAAATCCGCCCCCATCGAGACGCGCTCCGATCTTCACGGCACGCGCTCCTCGACGAGACAGCGCATGACGCGCCGGCGCTCGCCGCTATCGATCACGGCGCGTATCTCGAAAATTCTCGTTCCCATCTTGAAGCGCATGTGCGGCCCGAGCCCTGCTCTATGGCGAACCCAGATCTCGTGGCTCACACGCCCTTGAATCCCGTTGGCCTCGATACGTTCGCTGCCCGAGAGCGGCTCTACGGCTCCCCACACTTCGGCCACGAGCGACCACACGCGCGTCGCGCCGCCCCCGCCGTCGGCCGTATCGACTGGCTCTTCGAGCCCGAGCCTGTGCCTCATCTCCCCAAACGATACGCGCGTCACAGCCGCACCTCCCGATAGGGTTTCAAGAGATCCGATACGGCGTGTGGAATTGCGGCGCCCGCAGACCCGATCTCCATGGGATCGCGGTGCTCATACCAATGCGCGACCAGTAGCAGGATCGCGTGCCGGATCGGCTCCGGCACCTCTTCCGCCTCCGCGCCCATGCCGGCTTCGAAGTCGATCTCGATGCCGCTCACCGGCAGACCCGGTGCCGGCCAGCTTTCACCGTTGGGGACAAGCCTCGGCGTCAAGGCGTCCTGGTCGAGCAGATAGCGCTCGGGCGGCAGCACGTCCGGCGTGCCATCCGCACCGCGCACGCGCACCTCCTCGATGCTGTGCACGGGCCTCAGCGGAAAGCGCACCGCTGCATTTTTCGACGACCGCGGCTCAGGCCATTTGTCGAGCGTCAGGCGCCATTCCTGGCTAATCAGCGCGAGCCCGAGGGCGGCTTCGACGTGCAGCCGCGAGGTCACGATCAGGCTTGCGATCAGAATGTCCTCGGCGTCTCCGTCGATGCGCAGATGCGCCTTCGCTGCGCTCACCGAGACCGGCTCGACGGCAGGTGCGCCCATCAGGGTCAAAGCCATGCTTCCTCTCCTCATTGATCGATCAGCCCCCCAACGAGCGAAGCCGCCGGAGGGGGACCGGCGGCTTCGCTCTCACCCGGCGAGAGGGAGGAGACCCGCCGGGGTTTCTGTTTTCGCTCACGCGCCTGTTCGCGCGCCTTTCAGGCGCGCTGGCGCTCCGCGGGGGCGGCGCAGCTCATGCGGAGCTTGGCGCCCTCGCTCTTACTCCGCGAAGCGGAGCAGCTTGATCGCGTTGAAGTCCTGCACGCCGCCACCCACGCGCTTGGTCGTGTAGAAGAGGACGTAGGGCTTCGCCGAGTACGGATCGCGCAGCACGCGGATGCCCACCCGGTCGACGATGAGGTAGCCGCGCCGGAAGTCGCCGAAGGCCATGGCGTAGGCGCCGCTTGCGATCGCCGGCATGTCCTCGGATTCGATCACCGGATAGCCCATCAGAAGCGACGGCTCGCCCGCCGCCGCGGCCGGCTGCCACAGATAGGTGCCGTCGTCGTCCTTCATCTTGCGGATCGCCGCCTGCGTTCCGCGATTGAAGACGAACGTTCCGTTCGCCCGATACCCCGCCTTCAGCGTGTAGACGAGGTCGATCAGCTTGTCGGAGGGATTTTCGGCCGGAAACGCACCGTTCACGCCCGTCTTGATGTAGGCGATTTCGCCCCACTCCTCGTCGCCCGCAAGCTCCTTGGTGTAGCTCATGAAGCCCGTGGGCTCCGTCGTGCCATTGCCGCTGACGAAGGCCTTGCCTTCCTGCTCGGCAAACGTGCCCTGCACCTCCTCGGCAATCCATGCGTCGATGTCAACGGCGCTGTCGTCGAGCAGCGTCGCGGACGCCGCCGGCATAGCGTAAAGCTCCTTCGTCGCGAACGGGATCTCGACGAGTGTCGGCGTACTGGTTTGCGTTCGTGCCGTCGTCTCCGCCACCCAGCCGTGCGCAAATCCGGTCGTCGAGAACGGCTTCTTGTAGACCGAGCCCGACACCTGCCGCACGGATGCGATGGCGCGGATCGGCGAGATGTTTTTCAGCGCCGACATCACAGCCCGCTCCGTCTCGGGCGGAACGAGATAGCCGCCGTCGGCGCCGCTGTTCGTCGACACCGCGAGCGCCTTCTGCTCCAGGAGGTGAAGGCCTGCAGCGTCGCCCTTACGGACATAGGCATGAAAAGCTTGGCGGTGCTCGCGCACGGCGCCCGTCTCCGGCGCGCCGCCGCCGATATGCGGCCGCTCGGCCTTGAGCGCCAAGCGATCCGCCGTGCGCTTCGTTTCATCGATGGCGCGGTCGATCCGCGCCAGGCGCTCGTCGATCAGCGGGTCCGATGCCGAGCGGCGTTCGATTTCGCCGAGCCGCTCGTCGTTCGTCTCCTTGTAAGCTTCGAACGCGCGCATAAAATCTTCGAATGCCGCGCTCACGCTGCCGCCGGCTTTCGTTTCGATGTCGTCATGGTCTGCCATATCGATGCTGTCCTTGTGGATGCCTGTGTTCACGTCACGACCGGAGAGCGATGGCTGCTTCCCGCATGCGGGCCGCAAGCTGAGCCTCCGTCGTCATGCCTCCGCCCGCATCCCGCAGGGCTTTGAGGCCTGAGAGCCCCGAGCGGAGCACCGCGCGGGCCTCGCCTCGCGTCAGCCCAGCATCCCGCGTGAGCCACCGCTCGAATTCGCGCTCGGTCGGAGGGCCCGACGCGAACGGCTTCTGTTTCGTTGTCGTGATCCGCGCTTCGGGCAGCAGCGGAAACGTCACGATGGAAATCTCCCAAAGATCGATCTTGTCGATCCTGCGCACCCCCGATGCCTTGTCGCGCCGCGCCTTCACCGTACGAAAGCCGATGGAAAGTCCGTCGAGCGCGCCGGCCCGCATCAGCGCCATCACCTCGCGCGCTTTCGATACCTCGCGCATCAGGCGGCCCTGTGCGTAGAGCCCGCGCGCATCTTCCCGCAGCACCGTCCAGACCCCGATCGGCTGGTTCGAGTCGTGCTGAAAGAGCAGCTTGACGCCGCGCGGCCCGCGGCTCGCCAGGCTTTCGCGGAATGCGCCCGGCATGACGACGTCGCGTCCCAGGTCCTCGCGGTTGAACAGGCTTGCGTAGCCCTCGAACGTTCCGTCGGCCTCCGTGTGCTTGAAGTCGAGCGAGACGAATTTCATCTCGGGTGCCGGGGCCGGCACGCCCCCGCGCGTCGTCGTTCGGTTCGCTTGAGAAGCGCCCATTCATGGAACTCCGGATTTATCTGGTGTCTGTTCGAAGCGGCGATGCGGGCCCTTGGTCTCCGCCGCTTACTCTTCCGAGGGCAAGTCGGCGATCGCCTCAGTCTCTAGCGGCGCATAGCCCACTGCCGCGCGCTTCTCGTTCTGCGTCAGGAAACTCACCCTTTCGATGCGCGCCCAAAGCGCTTCGCGCTCGCTCGTCAACGCTTCGATCTGATCGAGATCGGGGCGCAGTTCGAGACGTCGCTCTCCATGCATCGAAGGCACGCTCGGTCTTGCCGTTTCCCACGCGGGCGCGAGCCATGACGACATGGCCTTCGCCGTGCGCACGACCAAAGGCAGCACGGTGCCGCGCCAAAACGCACGCTGCGCCTCCTGGTAATTCGAGTATGTGTTGTCGCCGGGGATGCCGAGCAGCATCGGCGGCACGCCGAACGCCAGCGCGATCTCCCGCGCCGCGCCGTTCCGCGCCTCGACGAAGTCCATATCCTTCGGCGACAGGCTGAGCGGCTTCCAATCGAGGCCGCCCTCCAACAGCAGGGGCCGCCCGGCGCGTTGAGGTCCTTGGAACCCATCGTCCAACTCCGCCTTCAGGCGCTCGAACTGCTCCGGCGTCATCCGCCCGTCCGCGCCGCCGTAGACCAGCGCTCCAGACGGGCGCGCCGAATTGTCGAGCAACGCCTTGTTCCAACGTCCCGCCGTGTTGTGAATGTCAATCGCCTGCGCGGCTGCCTCGACAGGGCTCATGCCATAGTGGTCGTTCGCCGGATGGAAGAGGCGCACGTGCAGGATCGGGCGCACGCCTTCGATCGGCTCTTCGTCGAAGCGCACGGTGCGCCCTGCACACGTGTATTCATAGGCTTCCGGCCAGCCCTCGCCGCCCGGCACCACTTTCATCCTGTCGGGCCTCAGCGCATAAAGCTCTCGCAGCTTTCCATCGACCGCAACCGCCTCGACATAGCCGTTGCCCGAGACGAGCAGATAGCCGTACCAGCTCTCCAGAAAATCCGCGCTCGTGTGGTCGACGCTCGGCCTCGCCAGAAGGTCGAGCAGCGGATGCTGTTCGATCTCCGCGTCGCCCTCGTACAGCAACAACGGCACGGACGCCGCCGCTTCCGAAATCATACGCACCGCGCGATAGACGATTGCGTTCTGCATGAAGCCTTCGCGGGCGAATGCCTCGTAGTCGCGCGGCGTCCAGACAGGGCGGCCGAGCGTCTCCAGCACGATCAGCGGTCCCGCTGCGCTCGCCTTCGCTTCGTTGGCGGACGGAAGAGCAGCAGACGGTTTCGCCCGGCCAGGCCAAAGGCCCGCCAGCGTCTCCAGAATACGCGGCATTGAGTGATCCTTGCTTCGATCTCGTCTTTATAGCTGCCGGATTCCCGGCTGGGCCGTGCGCTCGATCATCAAATCGGTCAGCGCCCACACCAGCGCGTCCACACGATCCGGACTTCTCCCTCGCGACAGCCCGTCCGCGCCGAAGGCGAGCATCTGCTCTTCGAGTATCGCGTGCACACCCACATGTGCCACACGGCCCTCGGCATAGAGCGCGGCCACCGGCTCCGCTCTCAGCCACTTACCGCGCGTTGCACGCACCTTGCGGACAGCGACGGCCTCGTCGATCTGGCGCAAAACCGAGACCACGAGATCGCCGCCCTGGTTCACCTCCGCGACGACGCGGTCGGCCATGAATTCGTGGTACGCCCGCACGGCCGCACGCGCCCATACGTCCGGCGAACGACCTTGCAGCGTGCGGTCGGCCGCGATGTACGCACGCCCGTCTGCGCCGATGCCTGCAACGACGATCCCGCACGCGTCAGAGCGCGCGGTCGCCGTCACCGGCGGATCGACGGCGACGACGATGTTTCTCAGCTCAGGACACACCGCGACGCGCGCTTGCTCGATCCAATCCCGCCGCCACAGGCTGCCGGATTGCTCATCGACGATTTCGCCCAGCAATTCCTGTCGTCCCAACGCCGTCCCGGCGTAGCGCCGCTCCATCTCGGCGATGAATGCAGGCGCCAGATGTGCCGCGTTGGCCGCGGTCGCGGCTCGCGTGATCGCGGTCGCCGGATCACTCATGATGCTCTTCAACAGCGGTAGCGGCTTCGGCGTCGTCGTGACCGCAATCGCCGGTGCCGTTCCGAGGCGCAGACCGAATTGCAGCATGTCCCACGTCTCTTCCGCGTAGCGCCACTTTGCAAGCTCGTCACACCAGGCCGCGTCGAACTGCGGCCCGCGCAGGCTGTTCGGGTCTTCCGCCGAAAACATCTGCGCGATGCTTCCATTCGGCCAGACAAGCTGCGACTTCGAAACTTCGAACGCCGGGCGTTCATTGTCTCCGTGGATCGCCAGCAATCCCGATACGCCTTCGATCATCACGCGGCGGACATCGGCAAGGGTTTCACCCACCAGCGCAATGCGACTGGCGCGCTCCGCACCGAGCGGCGGAATGCCGAGCGCTTTGGCGCGCACCCATTCCGCACCGGCCCGCGTCTTTCCCGCGCCACGCCCGCCGAGGATCAGCCAAACGCGCCAATCGCCGCCGGTTCGGGTTTGACCGGGCGGCAACTGATCGTCGCGCGCCCATATCTGCCAATCGGCGAGGATGAAGCTGAGGCTCTCACGATCGAGACTTGCCAGATGGTCGGCCAGCAGGCCCGACGCCGCCGAGGCGCTCAAGACGCTCCGCAATTTCGCGGCGCATGCGCTCCGCAT

Protein sequences of DBSCAN-SWA_2

>NC_022997|2558618:2617656|2572895_2575643_-|WP_081717719.1|DBSCAN-SWA
MRQAPLAFSYETNTEYQPMTSSAAQSFINVGERTNVTGSAKFRKLIEANDYAAALAVARQQVEAGAMVIDINMDEGLLDSEKAMTTFLNLIASEPDIARVPVMIDSSKWTVIEAGLKCVQGKAIVNSISMKEGEEQFVEQARKVLRYGAAVVVMAFDEVGQADTIERKVQICERAYKILTEQVGFPPEDIIFDPNIFAVATGIEEHNGYGIAFIEAARQIREKMPLTHISGGVSNLSFAFRGNEPVREAMHAVFLYHAIKAGMDMGIVNAGQLALYDDIPAELRELSEDVILNRRPDATDRLLEAAPRFKGDGSGAKAKEKDLSWREGTVQERLTHSLVHGITDFIEADTEEARQQAEKPLHVIEGPLMTGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLQPYLEEEKRLSGVDQMPAAGKVVMATVKGDVHDIGKNIVGVVLQCNNYEVIDLGVMVPAAKILEAAKKEKADIIGLSGLITPSLDEMCFVAAEMEREGFSVPLLIGGATTSRVHTAVKISPNYERGQAIYVLDASRAVGVVSNLLSETESKPYIENIKTEYVQVREKHLANEARKQRIPISAARANKFDIDWSQYAPPKPSFLGTRTFKNYDLGSLVPYIDWTPFFQTWELTGRYPAILDDNKVGTEARKLFADARELLDRIVAEKWFTAHAVVGFWPANGVGDDIELYTDETRKERRATLHTLRQQIARDPSRNRAHTALADFVAPKESGLADYVGGFAVTAGHGEDEAINAHIKATDDYSRIIAKALADRLAEAFAEAMHAKVRRELWGYGKGEKLSNEDMILEKYQGIRPAPGYPAQPDHTEKATLWDLMRVKEETGIEITESFAMWPGSSVSGLYFAHPESHYFGVGKVERDQVEDYARRKGMSVAEAERWLAPVLNYDAVAEAKNVA
>NC_022997|2558618:2617656|2583451_2584612_+|WP_023787813.1|DBSCAN-SWA
MAQTLSACPRETCAPTDQAVAIRPIPAALAGFRDGGGPLRLLQAATLVHAGALALPLATPIELPVTALLAGASLTALLALALPRLSAQPAEEARKDGPADVATDDLSPKVEGSGASPSPLPFIGERIVPGRDDTAQLAVLARAAQRLRRVSPVRRQIWADLTARVSHELRTPLNAVIGFSDVLDAELFGPVGHPRYREYARHIRDSSRELLKSAEDTLAITCLLDHDPEARADARVDFKAAVGEAWAFHSEPPSLHGLTLEAQIPEGLEVLIEHRPLKQILINLFAEAVRRSDARGTVGLVATVDGDLVQIEVFLRGRPDSTSVGQASLPVSLAHALLELQGATLIEVDDPHATWRVVTVLECAAQNDFFATPAYQEMRAPVQQAC
>NC_022997|2558618:2617656|2611231_2611642_-|WP_023787838.1|DBSCAN-SWA
MSSAAWELQKAVYGALVANADLVAALGGARIYDEVPRGAAFPYVTLGPTTTRDWSTGTEEGAEHALTLMAWSKAPGAREVHLVLDALRAALHEAALSVSGQRLVSIRHEASDTVRERDGETWQGIARFRAVTEPNP
>NC_022997|2558618:2617656|2600145_2601516_-|WP_041316516.1|DBSCAN-SWA
MKLKSLAFRLFATSAAWTLLVLPIAGLIIYELYRDDVQATFDARLEKLVYAIAVDSMVGAATPIAPNNRYEPLFEDIHSGWYWQIQPIDDATAPRLGSASLDGAEIDIPFRHNIKPDANGARWMNSTGPMGEQLRMVEVIDTPYYHREGPRYSVLVAGPIDWLESRVANFLTRLAVALALTGIGLVTVTLFQVRFGLLPLQRIEQGLAEIRSGAAGKLDGELPAEIEPLQVELNALIASNQEIVDRARTQVGNLAHALKTPLAVITNEAREDKGPLGDKIAEQAEIMRDQVNHYLDRARMAAQVRVIGRATPVLDVLEPLKRALERIHRDRAIDIEIACPPHVRFAGERQDLEEILGNVCDNACKWAESEVKVRVAADNRRIPGRVEITVEDDGPGLSDEERARIGKRGVRLDETKPGSGLGLSIVTDLVQSYRGTLKLAPSTMGGLLVRMELPSA
>NC_022997|2558618:2617656|2560703_2562071_-|WP_023787792.1|DBSCAN-SWA
MKRKIRAVLMADIAAARSSGSADDPGAPVRLDSYRAVVRDVVAHGGGEMLTASDEGALIAAFQSAVAVMRAAVDMQETLRARNKALSLTERMDVRIGIAIAEVPAGEGEVPPETHAAVRALADLAAPGGLCVSQSLREAVAGKLHLAFQPVTPDGAALDGLAPATYRVAVGSAEPARRKRALPQWSVAPKHAASVAAALLIGALAWLVLPRSEPAPEPSADGPAEAGLPLPGPSSADVTAASTPPADARPSGTLVFKPAHAPNPSAVLSARKMLPNAWRDCEGGEPSKAIEGCQLLIDSGLAQDAELAEFHLRQGKALRDRGDFDRALSSITTALSIAPTPAAYALRGTVLYKKQNFDAAIADYSEAIRRDARNGEALNNRAWTYYRMGRARDALPDADAAVRLLAKQAYAWDTRAHIHAALGDREAAIRDFRAALAIDPAYADSKAGLAKLGAH
>NC_022997|2558618:2617656|2569033_2569564_-|WP_023787801.1|DBSCAN-SWA
MALYDLDDTRVETPADGNFWVAPNAVVLGKVRIETDASVWFGAVLRGDNELIRIGARSNVQDGCVLHTDPGFPLDIAEDCTVGHMAMLHGCTIGRGSLIGIGAVILNGAKIGEECVIGANALIPEGKVIPPRSMVLGSPGKIVRELTDEDVARFGKGAGRYVANWKRYKAGFRPAP
>NC_022997|2558618:2617656|2612942_2614187_-|WP_041318612.1|capsid|DBSCAN-SWA
MADHDDIETKAGGSVSAAFEDFMRAFEAYKETNDERLGEIERRSASDPLIDERLARIDRAIDETKRTADRLALKAERPHIGGGAPETGAVREHRQAFHAYVRKGDAAGLHLLEQKALAVSTNSGADGGYLVPPETERAVMSALKNISPIRAIASVRQVSGSVYKKPFSTTGFAHGWVAETTARTQTSTPTLVEIPFATKELYAMPAASATLLDDSAVDIDAWIAEEVQGTFAEQEGKAFVSGNGTTEPTGFMSYTKELAGDEEWGEIAYIKTGVNGAFPAENPSDKLIDLVYTLKAGYRANGTFVFNRGTQAAIRKMKDDDGTYLWQPAAAAGEPSLLMGYPVIESEDMPAIASGAYAMAFGDFRRGYLIVDRVGIRVLRDPYSAKPYVLFYTTKRVGGGVQDFNAIKLLRFAE
>NC_022997|2558618:2617656|2578402_2579419_-|WP_023787810.1|DBSCAN-SWA
MSGTLDTQELVGALKAAAEPTRLRILLLLAAGELNVKDLTQILGQSQPRISRHLKLLAEAGLIERFREGSWVYFHVSDRTEGGRLVRRLLDTVDPRDPILLRDGERADSQKREREATAQEYFRAHAADWDRIRALYVSEHAVDAAIVKAFDGATFDVFVDLGTGTGRMLELFAGRYTRGLGLDVNQSMLAYARSRLKTAGLAAAEVRHGDIYDLALPDRVADAVVMHQVLHYLSEPALAVREAARILAPGGRLLVVDFAPHEIEDLRARHAHERLGFEDRQVVSWLKDAGLSGVEVQSLAPDATDARQALTVSLWRASKPDVAVQPASKSQKLERIAP
>NC_022997|2558618:2617656|2614221_2614941_-|WP_023787843.1|head,protease|DBSCAN-SWA
MGASQANRTTTRGGVPAPAPEMKFVSLDFKHTEADGTFEGYASLFNREDLGRDVVMPGAFRESLASRGPRGVKLLFQHDSNQPIGVWTVLREDARGLYAQGRLMREVSKAREVMALMRAGALDGLSIGFRTVKARRDKASGVRRIDKIDLWEISIVTFPLLPEARITTTKQKPFASGPPTEREFERWLTRDAGLTRGEARAVLRSGLSGLKALRDAGGGMTTEAQLAARMREAAIALRS
>NC_022997|2558618:2617656|2597481_2597997_-|WP_023787824.1|DBSCAN-SWA
MTRKQRRGLLIGLGVGVLSLAAVLMMFAFRQSIVFFHTPSDIAEKKIEAGTRFRLGGLVENGSVARGEGTFVRFAVTDTLKSVPVSYEGILPDLFREGQGVVAEGTLGDDGHFVADTVLAKHDENYMPPEVAKALEERGVKLGPGATHPGGTEGTSSYGSGGNTYGGTETQ
>NC_022997|2558618:2617656|2591999_2593562_-|WP_051388552.1|DBSCAN-SWA
MLKSGDAQPGARNGPKSSLKRVGQRAGTALTMAACATLLIGGFALTPSVAQLKPADAGVETPFGRAPLSFADVIEKVKPSVVSISVTGSNRAAQRGGGAAPAPGQPSPFPDIPEDSPFYEFFKNLPREFRGQPQPRPTQAQGSGFLISEDGYVVTNNHVIDGAGRIQVSFDDQEKLEAELVGTDARTDLALLKIKAEGKTFPHVSFATNDARVGDWALAVGNPFGLGGTVTAGIVSAQGRDIGSGPYDFLQIDAAVNRGNSGGPTFNLQGEVIGVNTAIFSPSGGNVGIAFAVPARTAVEVINQLREKGAVSRGWLGVKIQNVDEDTAAAIGLTQSKGALVSEITPGGPAADSGLKAQDAILQVNTDEISDSRDLARKIAGYAPDTTVDVKVWRDNKEEIVKVKLGTFPGSAEEIARLEQGNPTDDTAGTELQQLGLTLAPIRTGEEGVSVSEVDPESDAAQKGVRAGDVILEVGGTVVNGPNDVVEGIRKAKELGRRAVMLSIKSQEQRRIVPIQLKQG
>NC_022997|2558618:2617656|2610234_2610408_-|WP_081717721.1|tail|DBSCAN-SWA
MAVGFGVLGLEPRAFWSLTLAELDAAVRGRFGATRAEEPPSRSDLSDLQDRYPDGPE
>NC_022997|2558618:2617656|2580726_2583321_+|WP_051388551.1|DBSCAN-SWA
MVDHVDLDVALDPEATRVKAQLKIRRNPAAEKGAAALALDGEHLVLDAITLDGKPLPERAYDLTETELVIHKVPARPFTLSVETTIDPEANKALQGLYRSRGVFCTQCEAEGFRRITFFPDRPDVLATYTCRIEADRATAPILLANGNPVERGRLKGGRHFAVWHDPHPKPSYLFALVGGDLGRIGSTFKTASGRKVDLNIYVEHGKEERAAWAMDSLKRSMRWDEVRFGREYDLEVFNIVAVSDFNMGAMENKGLNIFNDRLVLASPETATDDAFGRIESVVAHEYFHNWTGNRITCRDWFQLCLKEGLTVYRDQEFSADERSATVQRIQDVRTLRATQFAEDAGPLAHPVRPESYIEINNFYTATVYEKGAELVRMIETILGRDAFRAGMDLYFERHDGCAATIEDFIACFEDASKRDLSHFKLWYSQAGTPELVCSLAYDRHKKSAELKIEQALPPTPGDARKKPLHIPIRVGLIGGNGQEIPLVRDTGEAIEDGVLNLTRRSETFRFVDVPSAPVPSLLRGFSAPVNLTMSLSESDLAFLMAHDRDLFNRWQAANTFATRTLVDMVRRLKKGERATQRATAFARALEAAVSAPDLELAYRAELLKLPSQSDIAREIGRNVDPGLIFRAYRQLTRVVGSTLGAQLEDVYRATRDRGAFSPDAESAGRRALGNVALTLLAARGTAADVERLSDHFFNARNMTEEAHALVLIAGRSGTLREEALARFHDRWKDDHLVIDTWFAAQAQSPLRAALSQVKALTRHPLFSLTTPNKVRALIGAFALQNPVQFHRPDGAGYDFLAAQVLEIDGFNPSIAARLLGAFRAWATLESGRRAAAKKALQRIAKAGSLSRDVTEIVAKMLDQ
>NC_022997|2558618:2617656|2563695_2564664_+|WP_023787795.1|DBSCAN-SWA
MPATNGAGNVKIGLALGGGAARGWAHIGVLRALKKAGIQPDIIAGTSIGAVVGACDVAGHLDELEAFARELTRRRVLGYLDFNLSGTGLITGHRLGERLYKHLGDMRIEDLPRSFTAVATEIGTGHEVWLSRGSVVDAVRASYALPGVFRPVKVDGRWLFDGALVNPIPVSVCRAHGARYVIAVNLNIDISNRGTISNINPMPQSDGEMEAVPPVTGNNGIAVRRLLQRQILGRGDDTPGITTVMVDAFNIVQDRIARSRLAGDPPDAMISPRLHGIGLFDFYKAEELIARGEAAAQRTIEDLARELETRRALESGAAMPAH
>NC_022997|2558618:2617656|2584624_2585131_-|WP_144083588.1|DBSCAN-SWA
MSETSPPGTGSRRMKYLLIGSLALNLLFVGGLVGMSFKKHGHGPHHAAREHFGLMGLTRVLPEDRRKDVLEQLKKEYGEMRPAMEDLRTARIEAADRLAAEPFDRAALEQAIANVAGKEQALRATTVETFLVQAARLSADERKQLSERWRKRADWMAHRGKKNNKDKQ
>NC_022997|2558618:2617656|2568150_2568732_+|WP_041318583.1|DBSCAN-SWA
MPDVVVPETNTSSSPFMRVYGPAQPPYGFVRFCERNPDACRARHIEDIRFQPTPERLSELDEVNRWVNHAIAPATDMEIYGVSEFWTFPVDRGDCEDYALLKQKILIQRGWPKSSLLLTVVRDEKGEGHAVLTARTSQGDFVLDNKIDDVRLWNASGYYFLMRQSYLDPRVWVSLDVNDRTAPDAIAGVQDGR
>NC_022997|2558618:2617656|2577476_2578406_-|WP_023787809.1|DBSCAN-SWA
MTPQTSERKSRLLGAGEIDVSFEFFPPKSEKMEQALWAAIERLSPLCPSFVSVTYGAGGSTRERTHTTVARIINETALKPAAHLTCVDASREEVDAVAQAYWDAGVRHIVALRGDPASGVGQSYIPTPGGYQNAADLVAGLKRIANFEISVAGYPEKHPESASLKSDIDNLKAKVDAGADRIITQFGFDNTHYLRFLERARAAGIWVPITPGIVPIHSFRQVAGFAVRTGASVPAWLARRFEGLDEDPATTHLVAAAVATEQVMDLVDEGVKSFHFYTLNRADLVYAICHLLGLRPLRAAPLEARKAAS
>NC_022997|2558618:2617656|2593656_2594904_+|WP_023787821.1|DBSCAN-SWA
MRRRFSVFSVFSLSLAAALLTALSLAPGRAGPLWPNAAPASAPDRSPVDRIAVFGADDRIPLPDDRADLTASIGLIYEPGSQSVCTAFCVGDDVAATAGHCLFRTAGEHAPRLQGFTFRLAPKGAREAVTRIAGAQQSGAPQNVAAGTLKLRVRPPIDASSDWALMRLEEPICKGRSLPLSRQPADKLVELSTAQRVYQVSYHRDFGNWELALGHPCAIRRSFAGADWETISKDFTDARHVILHTCDTGEASSGSPMLTDGPAGPEVVGINVGTYLQSRVLTQQGQVVHRYKSKTVANTAVSAEAFRSVLDALLRADILAARDEMRALQRLLASEGYAVGAEDGRYGPKLSTAIRAFEQAEGRAVTGLATVELLKRLSARDAERRGAQPSPSQSLHIETGSVGGYDGPRKRRKTR
>NC_022997|2558618:2617656|2608105_2608978_-|WP_023787832.1|DBSCAN-SWA
MKQLPSGLEAHLTSGATTLCWCWRLARRDGVVMGFTDHDRDVAFGGTVYEAAAGMGASEIRDAVGLGVDNLEVTSAMTSERLAEGDLAAGIYDNAEVEIYRVNWMTPAERVLMRRGNLGEVKRSGKAFAAEVRGLAHLLQQTKGRIFQYACDADLGDARCRVALANGEFTGSGALQNIDSPRRFTASGLAAFASGWFTHGLLSFTSGAAEGQKVEVKSHTHAGGVVTVELWSQARLPLAPGQTFTVSAGCDKRLTTCRAKFANAVNFRGFPHMPGNDFLTAVRRPGATSR
>NC_022997|2558618:2617656|2565395_2566136_-|WP_023787797.1|protease|DBSCAN-SWA
MTPTDTSQEPVFNVPNCVVGVLAVLVLVHLGRTVLTSEGDLWFVLASAFIPGRYGPLGEVLPGGELAKLTSPFTHMLVHGDWIHLALNSAWLLAFGGAIAARTGAVRFLAFFILSGLGGALAFYIANEGQMTPMIGASGAISGLLGGTLRILFPAMNNGGFRRLREAPRSIPLMPLGETLTDRRVIVTSAVLVLINVLTIIGFGAAQNSAGIAWEAHLGGYAIGIFTYGLFDDVSRFADDPQLDTD
>NC_022997|2558618:2617656|2585127_2585652_-|WP_023787815.1|DBSCAN-SWA
MTENGRIEGDGLTAFEQVLERYGSDRTRWPAPVRMRFARLLSEDDAAGQRLKEAEALDRLLDLAPPPAVDSRMLADRIMAAVDAEAGAPTRQVPNRVWNPEIVRKRVATSGRTHGPAAALLAASLVLGMFSGLSGTFDTAVPPMVADAAYEGDVDLGQIAFDSNATSFFEEDYL
>NC_022997|2558618:2617656|2594911_2595427_-|WP_023787822.1|DBSCAN-SWA
MRFAASVVLGVAVLFAAVSWGGDALALQPDEILSDAALEKRARGLSAELRCLVCQNQSIDDSDAPLARDLRLLVRERLVAGDTDTEVRDFVVARYGEFVLLKPPFSVETLLLWFIPLLALLAAVAILWSSFRAGQTTAHEPVGEVSAGSALTPDEQAKLDALLAEKTDGKA
>NC_022997|2558618:2617656|2615007_2616276_-|WP_023787844.1|portal|DBSCAN-SWA
MPRILETLAGLWPGRAKPSAALPSANEAKASAAGPLIVLETLGRPVWTPRDYEAFAREGFMQNAIVYRAVRMISEAAASVPLLLYEGDAEIEQHPLLDLLARPSVDHTSADFLESWYGYLLVSGNGYVEAVAVDGKLRELYALRPDRMKVVPGGEGWPEAYEYTCAGRTVRFDEEPIEGVRPILHVRLFHPANDHYGMSPVEAAAQAIDIHNTAGRWNKALLDNSARPSGALVYGGADGRMTPEQFERLKAELDDGFQGPQRAGRPLLLEGGLDWKPLSLSPKDMDFVEARNGAAREIALAFGVPPMLLGIPGDNTYSNYQEAQRAFWRGTVLPLVVRTAKAMSSWLAPAWETARPSVPSMHGERRLELRPDLDQIEALTSEREALWARIERVSFLTQNEKRAAVGYAPLETEAIADLPSEE
>NC_022997|2558618:2617656|2585722_2586364_-|WP_081717857.1|DBSCAN-SWA
MVGSGPTGPKGSTPGGPRGDVRQGPWPDAAEDRALLARVGRQDRQAFRTLVDRHLGAIVILARRMLKDEAEAEDIAQEALLRLWRSGETLELGPYGLRPWLRRVTSNLCLDRIRQSRRTVVTDEVPEIEEAPTQMANLEEQDLARRVGEAMAALPERQRRALTLFHHEGLSQAEVGEVLGVSDEAVESLLARARRALRVSLEKDWKGLLQSDA
>NC_022997|2558618:2617656|2599413_2599884_-|WP_023787826.1|DBSCAN-SWA
MRTLCASALLIVSIGLAGCGPEGPSKADTGMVVGAVAGGILGNQVGKGGGNIAATAIGAVVGGIVGSEIGRSMDEQDRRLAQEAEFDALERGQSGVSRQWRNPDNGRYGEVVPSRPYKRGQIDCRDYTHKIYIDGRPQSMRGTACRNPDGTWSNVA
>NC_022997|2558618:2617656|2610798_2611212_-|WP_023787837.1|tail|DBSCAN-SWA
MAAQKGKDLLLKVDSNGSGSFTTVAGLRARAIAFNAETVDVTHQESAGQWRELLAGAGVKSARLSGSGIFKDEESDALIRSYVFDGTIRDWQVVVPDFGVVEGAFQITSFELTGRHDGEVAFEIALESAGALSFDAD
>NC_022997|2558618:2617656|2602335_2603628_-|WP_023787829.1|DBSCAN-SWA
MDDARWLKEAWREFGQAEQAGARANPRIVSLFRDAGHPKVTRDEVAWCAAYLGACLERAGTRSTRSLMARSYLSWGQRLSEPRMGAVAVFSRGRNPALGHVGFWLGETDEHVVLLGGNQGNAVSVARYPKSRLLDLRWPEMRAETQQDETLFERALAHVLKMEGGYTDDPHDPGGPTNKGITLAVFALWRKVRLSAANRARMVRDLKRIDDATVREIYRRRYWDVARCAEMPAPLALMHFDAAVNHGPVTAIRILQEAVGTTVDGKIGPLTRAAISRMPLADALAAYAAIRERRYRALPHFPRFGRGWLRRVNATLKLARAIEAETQREPSDKREGENEMSKTPTTSGNGKWWGHSITIWGTIVTMLSVVVPAMAPVTGIDISGDEVRDAGEQSVEAIQAVGALIGTLLTIFGRMRASQPIARALFKGKE
>NC_022997|2558618:2617656|2589448_2590909_-|WP_023787818.1|DBSCAN-SWA
MTAASDLILRVISTQAFRLAAMSAAGFLLVSALIVGVLFWQTNTVLTDHVVDELRAEAAELARTLAGADAKTVAETVRLRSGVGGAGLYLLWDPARGKIAGNVAAVPPELAANPGGGRVFRYRPKDAPGTSRLGVGIPIATGSGLSLVIGRDVEDQVALADRIKRTFLWGFGALALAALIAGIWIGRSVLGRIEVINATASSIMAGDLSRRVPVSGSHDELDTLSESLNAMLDRIEQLMSGLKEVSDNIAHDLKTPLNRLRNSAEAALRDSRGAEAYREGLESTIEKADELIKTFNALLLIARLEAGVVEESAEAFDLGSLVRDVAELYEPVAEEAGLGLEIEAGEGMSIRANRQLVGQAVANLVDNAIKYSARYAACAAEERGASNAATATAVAVRVTNQGDTAEISVADRGPGIAAEDRERALRRFVRLEKSRTQPGTGLGLSLVAAVARLHNGSVRLEDNDPGLRVVVTLPLARRQRAVSGPV
>NC_022997|2558618:2617656|2569868_2570744_-|WP_023787803.1|DBSCAN-SWA
MNSAKQPVQAGKGERRTPSRRAGDDPIWLALRSEAEAAMAAEPALTGFIYATVASHENLEDAICHRIAQRLGHADVDAGLIVQTFRDVLASQPELGRAFRADLAAVIERDPATARYLDPFLYFKGFHALVTHRFAHELWRQGRRDFALYMQSQSSRMFSVDIHPAARIGKGLMLDHATGIVIGETATIGDNCSFLHAVTLGGSGKQTGDRHPKIGSCVLIGAGAKVLGNIHVGNSSRIAAGSVVLSDVPPHVTVAGVPARIVGPAGAEPGRTMDQTFESDPGIGPDDYAML
>NC_022997|2558618:2617656|2611824_2612130_-|WP_041318607.1|head|DBSCAN-SWA
MRHRLGLEEPVDTADGGGGATRVWSLVAEVWGAVEPLSGSERIEANGIQGRVSHEIWVRHRAGLGPHMRFKMGTRIFEIRAVIDSGERRRVMRCLVEERVP
>NC_022997|2558618:2617656|2563115_2563541_+|WP_023787794.1|DBSCAN-SWA
MIDTSPSPPARNAAKAEVEQGARFLPKLDSDGLIGAVVTDYDTGTVLMFAWMNETALKLTFETGIVHFWSRSRARLWKKGEESGNTLHLREARVDCDQDMLWIRADVAGAGVACHTGAHSCFYRTISTDADGTLVLTRDEI
>NC_022997|2558618:2617656|2575639_2576341_-|WP_023787807.1|DBSCAN-SWA
MTTLKFEDQKFPENVTLDDYAKLAEQFIPGRRAIFSIVEAALLELLADGPSKILVVGAGGGEEILRLGANNPNWSFVGVDTYQPMVELAHRRLAETPVGARARVETTTIEALEDDGFDAATCILTAHFVPDDGAKAAFLKAIHSRLKPGAPLAIVDGVGVAGEDKTELLRRIWKRHAVCNGVSPDVAESNAENFKKVAVVSEEREEALLASAGFERLTPIFRGLAIKGWLAFA
>NC_022997|2558618:2617656|2566384_2567068_+|WP_023787798.1|DBSCAN-SWA
MQAVAQFQHRATQALYAYWNDVRAGRRAPRRLEIQPAQLGGLLLDTFILERTDRSTYLFRLAGTRVSNWLGADLRTRNFLSCWGEADRAMLERHLAAISELGRVGVFTGEGYLSDTAAPAGSRAAASFELIVLPLMHTGHAIDRLLCLLVPLDDRAADAHSPRRGLKLLAAEEIWPEGVSREPFMDPPPALNPNVRMARIVRQGRRQFRVYQGGRVGEAPQADAERP
>NC_022997|2558618:2617656|2597993_2599208_-|WP_023787825.1|DBSCAN-SWA
MLLWVSFAILTAAVVAYLLRPLRQAQGPAAIASEAADVAVYRDQLKELDAERERGLIPANEHASARAEIARRLIKRAGKAESVAAEAERAGENSKFARRIYASMAALVPLLGIVLYLGMGSPHLPAQPFAARDTGPGSEIAIAGLIQRVEERLREHPEDGQGWDVIAPIYLRIGRYPEAAHAYAEANRLQGESDRRLLGFAEATLLAESGVVTEPVRTAALRLLQLDATHVQPRVWLALAREQDGDLAGAVADYRTLLSGAPDDAPWRDAVAERLLLVEARLRGEKVEAQPAPGTADGPQSAAPNEGEVSVNPADVSSMSREEQDAFVGDMVARLAARLEETPQDIEGWLRLARAYKVLGRDDDARLAIVKARGAFAGDQEALGRIAGAETALGLGAKEDRTTP
>NC_022997|2558618:2617656|2607618_2608191_-|WP_081717720.1|DBSCAN-SWA
MPSTFADFRTCPATISSPLSAGRGPRRAERQVIVKEQRARYRAHGGDEIVVAARRWIGTPYHHQASVVGVGADCLGLIRGVWREIYGEDAETPPGYSRDWGEASGKETLIEAALRHLVPRREGEPEIGDVLIFRMKPGAIAKHAALRATADTMIHAMEHCRAAEVPFSPWWRRRLAASFAFPGTVRSWPR
>NC_022997|2558618:2617656|2612150_2612741_-|WP_023787841.1|head,tail|DBSCAN-SWA
MALTLMGAPAVEPVSVSAAKAHLRIDGDAEDILIASLIVTSRLHVEAALGLALISQEWRLTLDKWPEPRSSKNAAVRFPLRPVHSIEEVRVRGADGTPDVLPPERYLLDQDALTPRLVPNGESWPAPGLPVSGIEIDFEAGMGAEAEEVPEPIRHAILLLVAHWYEHRDPMEIGSAGAAIPHAVSDLLKPYREVRL
>NC_022997|2558618:2617656|2558618_2560607_-|WP_023787791.1|tRNA|DBSCAN-SWA
MSEASEITITFPDGKSRQVAAGTSGLEIAKSISPSLAKRTVAMTLNGVLSDLADPIKQDAEIKFVARTDPEALELIRHDAAHVMAEAVQALWPGTQVTIGPVIDNGFFYDFAKAEPFEPDDIPKIEKKMGEIIAKNAPFTKEFWSRDDAKRFFRDKGELFKIELVDAIPEGEDLKIYKQGEWLDLCRGPHMTSTGAIGKAFKLMKFAGAYWRGDSTKPQLQRIYGTAWATEDELKAYLHQIEEAEKRDHRRLGREMDLFHFQEEAPGSVFWHPKGWTLFQTLIGYMRRAQQRAGYTEVNSPDMMEKHFWELSGHWENYGENMFTTTLPDERVFCCKPMNCPGHVQIFKHGLKSYRDLPLKIAEFGKVHRYEPSGALHGLLRVRHFTQDDAHIFCTEDQIKDECLKINDLMLAIYKDFGFEDIFIKLSTRPEKRVGSDELWDKAEAALSDVLEEVKRASNGRVKTALQPGEGAFYGPKLEYVLRDAIGREWQCGTTQVDFNLAGRLGAFYIDENSEKKTPVMIHRAMFGSLERFTGILIENFAGHFPLWLAPLQAVVAPIVSDANEYALDVVAELRAAGLRVDSDLRNEKINYKVREHSLAKVPVIVVVGKREAEERKVSIRRLGSQAQTVMTLDEALASLKDEATAPDLRSNGVAGEASVGT
>NC_022997|2558618:2617656|2609634_2610225_-|WP_023787834.1|tail|DBSCAN-SWA
MNEFNTPAETWTVAINADTTGLSSELRNAARLGRQFSTVLAGAFDGIAVKGRAVGDVLRTLALRLSDIVLKAALRPLEQGFGNLVSGLMSGGVAFAKGGAIRQGLPVPFASGGVIQSPISFPLAGGRFGIAGERGAEAIMPLSRGPDGRLGVAARGGAGVAVTFNVNTADAESFVRSEAQVAAMLARAVSFGQRNL
>NC_022997|2558618:2617656|2571021_2571822_+|WP_023787804.1|DBSCAN-SWA
MTDTPATPPDLRLEIEGPLAWIVADNPGRMNAFTADMWAKLPQHIQAAEADAAVRVIILRGAGTRAFSAGADISEFESARTGAAAADYDRLNHEAFDALLGASKPVIAMIHGFCLGGGLGIAACADLRLADHRAQFAIPAAKLGLGYNARWVQPLLALAAPAFVKEMLFTGRRVSGEEALRIGIVNTLTDADTLEIAVRTLAAEIAGNAPLTVSAAKLAIDELTRHPEQPDFAKLDAAVLACFESTDYAEGRRAFLEKRKPAFQGR
>NC_022997|2558618:2617656|2595437_2597426_-|WP_023787823.1|DBSCAN-SWA
MIVEIGHFALILALLVAAAQTIIPAWGAQKRDAALMAFGDTAASAQVVLILLSFLALTYAYVTSDFSVANVVANSHSTKPLIYRISGVWGNHEGSLLLWVLILALFGWAVAAYGNNLPATLKANVLAVQGSIAVAFLLFMLLTSNPFERLDPAPLDGRGLNPILQDPALAIHPPFLYMGYVGFSIAFSFAIAALIEGRTDAAWARWVRPWTLGAWMCLTVGIALGSWWAYYELGWGGWWFWDPVENASFMPWLVGTALLHSAIVMEKREALKVWTILLAILAFSLSLMGTFLVRSGVLTSVHAFAVDPDRGVFVLGILAFFTGGGLALFAWRARDLQQGGVFSPISREGALVLNNVLLTTGCVTVLVGTLYPLALESLTGTKISVGAPFFNMTFVPLMIPLLLAVPLGPLLAWKRADLAAASERLLAAGVLSILVIVATFALTERGPWIAPFCLAIGVWVMAGAVSEIAYRIKLGSAPVADSWRRFRGLPRAAIGTMLAHFGVGLMVCGIVGTSAYKSEQILLMRPNTTSEIAGYELTFRGAAPSRGPNYTETIGVFDVTRGGSAITQLMPSKRLYNAPPQPTSEAGIHASWRGDLYAVIGDQQPDGAFTVRLYFHPLVRFIWIGCFIMFIGGAVSLSDRRLRIGAPQRAARTTPPAGVPAE
>NC_022997|2558618:2617656|2610407_2610782_-|WP_023787836.1|DBSCAN-SWA
MANRHRGEIDAVLDGKPYRLCLTLGALAELESAFGDEDMLALATRFEAGRISARDCQRIIGAGLRGAGFDVSDLAVSAMRVEGGAAGYVDIVARLLATTFSARSGGDGSDCEGGEAAGPFPGRT
>NC_022997|2558618:2617656|2562194_2562500_-|WP_023787793.1|DBSCAN-SWA
MSWTKRLLQAPIHAYRWTLKPLMGLECRHLPTCSEYAIGSIEKNGAWRGLWLTASRLSRCHPWGSSGYDPVPDIQGEQHTFAPWRYGRWSRKRSVPPSEIS
>NC_022997|2558618:2617656|2601505_2602177_-|WP_023787828.1|DBSCAN-SWA
MRILVVEDDKDLNRQLNAALTGAGYAVDQAFDGEEGYFLGDTEPYDVVILDLGLPKMDGISILEQWRRASRNMPVIILTARDRWSDKVSGMDAGADDYLAKPFHMEELLARVRAQVRRASGHAKSEIECGPVRLDTKTARVTCDGQQVKLTSHEYRLLAYLMHHGGRVVSRTELVEHLYEQDFDRDSNTIEVFIGRLRKKLPADVIETVRGLGYRMSRGADEA
>NC_022997|2558618:2617656|2576345_2577407_-|WP_023787808.1|DBSCAN-SWA
MKVIESAEALEKAASERILIIDGAMGTMIQRHKLTEEDYRGERFKDWPRDVKGNNDLLVLTQPAIIQEIHEQYLEAGADIVETNTFNAQVISMADYGMEELSYEINVAAAKLARAAVDKYNAKTPDKPRFVAGAVGPTNRTASLSPDVNNPGYRNVTFDDLREAYKEQVLGLIEGGSDIILIETIFDTLNAKAAGVATLEAFDEKGLTLPIMISGTITDRSGRTLSGQTAEAFWYSMRHLRPFSIGLNCALGAELMRPYVAELSQVANVRISAYPNAGLPNAMGGYDEDAQEMADKTEPWSKDGLINLIGGCCGSTPDHIREIAARAAKYRPREIPEIAPKMRLSGLEPFVHG
>NC_022997|2558618:2617656|2579923_2580526_+|WP_023787811.1|DBSCAN-SWA
MTMVGQSRFHGRAAYVFGAAALALLVLVASTMSASAQQSPAAYMQRVANELIAAQRSGSQADFARVIRSHADVPSIAINALGSYAASLKKSDRPAYYAGMVNFIARYAATEGPKYPVARAVMTGQTRETAQGTFVDSRITLSSGTSYDVRWRIVRRGSAYKVRDAEIIGFEMTSFLNTLFQNYISENGGNPRTLVLALNR
>NC_022997|2558618:2617656|2567323_2567953_+|WP_023787799.1|DBSCAN-SWA
MSASPANHIRSSIRLDTRIVPDRRRHKRFHLALLGRFMRANKQEFPCRLNDISVGGAAVMSPVEVEMGERIVAYFDEIGGLEGEVARLFDGGFGMRFRVSQHKREKLAAQITWLVNKAELGDSFGRKHKRFELVNKTSTLKLPDGSSVDCRVLDVSLSGASIGTEARPSPGDVVMLGKLRCKVMRYHDRGIGVQFLDIPDPEALRRYFG
>NC_022997|2558618:2617656|2608974_2609613_-|WP_023787833.1|DBSCAN-SWA
MSFHEIRFPTGISRGAQGGPERRTDVVVLGSGFEERNTRWLASRRSYDAGYGVRSLDALHEVIAFFEERRGRFHGFRWRDHTDWKSGAPGAQTTAFDQVIGEGDSSARAFQLRKTYGALHAPFVRDIAKPVAGSVKVAVNGAVRIEGTHFSVDAATGMVLFGEEETPAADTVVTAGFEFDVPVRFDTDKLEINLSGFQSGAIPRIPIVEIRL
>NC_022997|2558618:2617656|2564779_2565211_-|WP_023787796.1|DBSCAN-SWA
MNVASILKAKGRAVTTARPNATLLDVAKKLGPKKIGAVVVVGDNGHVTGIISERDIIRAVSEHGAAALSMVVSDVMTRNVIACGETSELDELMEMMTKGRFRHLPVIEDDALVGIISIGDVVHHHVAEVEMEVSAMRNYLATG
>NC_022997|2558618:2617656|2616303_2617656_-|WP_023787845.1|DBSCAN-SWA
MRSACAAKLRSVLSASAASGLLADHLASLDRESLSFILADWQIWARDDQLPPGQTRTGGDWRVWLILGGRGAGKTRAGAEWVRAKALGIPPLGAERASRIALVGETLADVRRVMIEGVSGLLAIHGDNERPAFEVSKSQLVWPNGSIAQMFSAEDPNSLRGPQFDAAWCDELAKWRYAEETWDMLQFGLRLGTAPAIAVTTTPKPLPLLKSIMSDPATAITRAATAANAAHLAPAFIAEMERRYAGTALGRQELLGEIVDEQSGSLWRRDWIEQARVAVCPELRNIVVAVDPPVTATARSDACGIVVAGIGADGRAYIAADRTLQGRSPDVWARAAVRAYHEFMADRVVAEVNQGGDLVVSVLRQIDEAVAVRKVRATRGKWLRAEPVAALYAEGRVAHVGVHAILEEQMLAFGADGLSRGRSPDRVDALVWALTDLMIERTAQPGIRQL
>NC_022997|2558618:2617656|2569577_2569793_-|WP_023787802.1|DBSCAN-SWA
MKKDELAKVEAYLRKTFGTKNLSVRARPKKDDSAEVYIGDDFVAVLFREEEEGEVSYQFQMAILEMDLEEA
>NC_022997|2558618:2617656|2590892_2591573_-|WP_023787819.1|DBSCAN-SWA
MRVLVIEDDRETAQFLQKSLKESGHSADTAGDGETGLSMAQGGAYDILIVDRMLPRLDGLSVVKTLRSEGSRTPVLILSALGDVDDRVKGLRAGGDDYLTKPYAYTELLARIEALGRRAVPEEQETRYAVGDLVLDRLSHRVTRAGEQIQLQPREYRLLEYLMKNAGQVVTRTMLLENVWDYHFDPQTNVIDVHVSRLRSKIDKGFDKPLLHTVRGAGYMVRDGSL
>NC_022997|2558618:2617656|2586466_2589418_-|WP_023787817.1|DBSCAN-SWA
MPGEHAAQGPLIARIDAASRLPQDPADGASLHPLLADWRKSEARAGLVDVIEHEPVRTLIAGVVAGSPYLKSEIVRNPDRLEAILRDSPEQRFATLTQTLATRLAEISEITEAMTALRIYKAEVALMTALADLGGVWGVMQVTRVLSEAADAALRGAVRFLFRQAAAKGDWLPEDPEEPEQGSGYIVLAVGKYGAFELNYSSDIDLIVFYERALARLKPGLEAPTFFVRLTRDLVRLIDERTAAGYVFRTDLRLRPDAGATQIALSTDAAAQYYESFGQNWERAALIKARACAGDIEAGEAFLAELAPFIWRRNLDYAAIADIHAMKRQIHAFRGFGAGIGVAGHNIKLGPGGIREIEFFVQTQQLIAGGRQRNLRTRRTLDTLATLVALAWIEKPVADEIIGAYLYLREIEHRLQMVADEQTHVVPDDPVRLEAFARFAGYESTAAFSEALRAVLMPVQGHYARLFESAPELTAAGANLVFAGETDDPDTVAALARMGYARPSDVLAVVRGWHHGRYGAVRTARARELLTEVQPLLVQAFAETADPDRAITTFDRFLAALPAGVQLFSLLKANPPLMRLLADMMGTAPRLARILSRRRRLLDAVIDPRTFRALPTATELDEAIAAELKDAIDPQDVLDRARVIGSEQAFLIGVKVLSGAINAGEAGTAYAVLAERLIAAMVDDVEREMERVHGRIPGGGAVVVAMGKLGGRELSASSDLDLIVVYDFDPAANQSDGEKPLAPSQYYARYTQRLIAHLSAPTAEGTLYEVDMRLRPSGQKGPVAAQLSTFREYQATEAWTWEHLALTRARVITGPPELRSAVEAAIRDTLVRPRDRAVIAKDVQDMRARIAADKGTDRIWDLKQVRGGLVDLEFIAQHLQLMHAAAHPEVLDQNTLGAYRKLAEAGVLSGVDAERLTQATRLLHNLTQILRLCLEETFDPATAPSGLKALLARAGDAPDFSTLEAELAETLAGVATRFPELVT
>NC_022997|2558618:2617656|2603674_2607631_-|WP_023787830.1|tail|DBSCAN-SWA
MATLALAAVGAAAGSAILPAGVSMLGMTLSGAAIGSQIGAFAGSYIDNALFGPSGQRRTVEGPRLNDLHITSSTEGAPIPRLYGRARLGGQLIWADQIREHIVTTRTGGGSGKGGGQSKGSVTESTEYRYTASFAVALAEGQINGIGRVWADGGELDLALIKYRVHQGSDTQAQDTLIAALMGANAAPAYRGVAYVVFEDMPLGDYGNRIPQLSFEVHRAVEPFGDEIRGVCVIPGSGEFIYATTPVSKRLARGVSQSENVHTRQGGTDWSVGIDQLEATLPNANSISLIVSWFGTDLRAGDCEMKPGVEVSQKTTTPMTWSAAGLTRATAHLVSTKDGRPAYGGTPADAAVVQSIVDLKARGKSVVLTPFILMDVPGGNALPNPYGGIGQAAYPWRGRITCDPAPGASGSPDKASGAASQVAAFVGTAAVSDFAVSGSGVVYTGPNEWSYRRMILHYAHLAKAAGGVDAFLIGTEMRGLTQVRSDAASYPFVAALAALAADVKSVLGSGTKVTYAADWSEYFGHQPADGSGDVYFHLDPLWASPHIDAIGIDCYWPLADWRDGTSHVDYLAGARTIYDEEYLRSNVAGGEGFDWYYASAADREAQIRSPISDGHGSPWVFRYKDIRSWWQNPHFNRPGGTPSGTPTAWVPQSKPFWLMEIGCPAIDKGANQPNVFVDPKSSESFFPYFSRGTRDDLIQRRYLKALIETFDPASETYVAGRNPVSSVYGGRMVDLARIHVYCWDARPYPVFPYNLDVWSDGENWHFGHWLNGRFSVGALAEMVDAILADYGFENHDASRLAGIVPGYVIDRLMSPRDALQPLELAYFFDSFESEGLIRFRHRGAEPPVLTLGEEDLVEERPGDALLTMTRAQETDLPASAKLSHIVASGDYRQAVAEARRLTGTSGRVARAELPIVLEHESASRIADAWLFETWAARERAAFKLPPSALGVEPGDVVSVETDGVGYLVRVTEIGERGLREIEGLSIDPDIYRGGMPRDRETVVEGVVFDGMPHVEFLDLPLLRGDERPEDGYVAAFQLPWPGSVAVLSSPEDAGYVLRAVASAPAVMGVTLDPLLPGPLGVIDKATRLRIAITGGDLASVTRLQLLAGANAAAMKNEAGGWEVIQFENATLVGTGIYELSNLLRGQGGTELERRSQLPEGATFVLLAGIARVSVAAGEIGLPLFWRYGPANRDIADRSYAGATHAFAGRGLKPLSPVHVRGVRAANNDLSLGWIRRTRVGGDGWDTAEVPLAEDAEAYEVDILDGDTVKRTIATATPDCVYAAAQQVDDFGSPQATVSVAVYQMSSAYGRGSAKFAVV
>NC_022997|2558618:2617656|2572364_2572712_-|WP_023787805.1|DBSCAN-SWA
MLGRLILLLLQIAVGWFGTTALMNYIKFGEFRLFIFAVVAAVVIFLIGIIAAVILKDVGSPSSATLSWALGFALIAAVLWTWGPQLPLLSEIPWGRIRAEYAVLAFAILGYHLKR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023787791.1|2558618_2560607_-|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.0e-123	37.0
WP_023787792.1|2560703_2562071_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_023787793.1|2562194_2562500_-	membrane protein insertion efficiency factor YidD	NA	NA	NA	NA
WP_023787794.1|2563115_2563541_+	phosphoribosyl-AMP cyclohydrolase	NA	NA	NA	NA
WP_023787795.1|2563695_2564664_+	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_023787796.1|2564779_2565211_-	CBS domain-containing protein	NA	NA	NA	NA
WP_023787797.1|2565395_2566136_-|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_023787798.1|2566384_2567068_+	PAS domain-containing protein	NA	NA	NA	NA
WP_023787799.1|2567323_2567953_+	PilZ domain-containing protein	NA	NA	NA	NA
WP_041318583.1|2568150_2568732_+	transglutaminase-like cysteine peptidase	NA	NA	NA	NA
WP_023787801.1|2569033_2569564_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_023787802.1|2569577_2569793_-	DUF3126 family protein	NA	NA	NA	NA
WP_023787803.1|2569868_2570744_-	serine O-acetyltransferase	NA	NA	NA	NA
WP_023787804.1|2571021_2571822_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_023787805.1|2572364_2572712_-	hypothetical protein	NA	NA	NA	NA
WP_081717719.1|2572895_2575643_-	methionine synthase	NA	NA	NA	NA
WP_023787807.1|2575639_2576341_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_023787808.1|2576345_2577407_-	homocysteine S-methyltransferase family protein	A0A140XBC7	Dickeya_phage	9.4e-15	57.4
WP_023787809.1|2577476_2578406_-	methylenetetrahydrofolate reductase [NAD(P)H]	NA	NA	NA	NA
WP_023787810.1|2578402_2579419_-	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_023787811.1|2579923_2580526_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_051388551.1|2580726_2583321_+	aminopeptidase N	NA	NA	NA	NA
WP_023787813.1|2583451_2584612_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_144083588.1|2584624_2585131_-	periplasmic heavy metal sensor	NA	NA	NA	NA
WP_023787815.1|2585127_2585652_-	hypothetical protein	NA	NA	NA	NA
WP_081717857.1|2585722_2586364_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_023787817.1|2586466_2589418_-	bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase	NA	NA	NA	NA
WP_023787818.1|2589448_2590909_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_023787819.1|2590892_2591573_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.3e-28	33.0
WP_051388552.1|2591999_2593562_-	Do family serine endopeptidase	A0A1B1IT49	uncultured_Mediterranean_phage	6.6e-25	28.7
WP_023787821.1|2593656_2594904_+	peptidoglycan-binding protein	NA	NA	NA	NA
WP_023787822.1|2594911_2595427_-	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_023787823.1|2595437_2597426_-	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_023787824.1|2597481_2597997_-	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_023787825.1|2597993_2599208_-	c-type cytochrome biogenesis protein CcmI	NA	NA	NA	NA
WP_023787826.1|2599413_2599884_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_041316516.1|2600145_2601516_-	two-component sensor histidine kinase	NA	NA	NA	NA
WP_023787828.1|2601505_2602177_-	response regulator transcription factor	NA	NA	NA	NA
WP_023787829.1|2602335_2603628_-	TIGR02594 family protein	A0A249Y3Q7	Serratia_phage	1.2e-27	45.0
WP_023787830.1|2603674_2607631_-|tail	glycoside hydrolase/phage tail family protein	A0A0B5A7K5	Paracoccus_phage	6.2e-253	40.6
WP_081717720.1|2607618_2608191_-	C40 family peptidase	A0A1V0DYB6	Dinoroseobacter_phage	2.7e-32	50.7
WP_023787832.1|2608105_2608978_-	DUF2163 domain-containing protein	A0A0B5A5B8	Paracoccus_phage	6.2e-73	46.5
WP_023787833.1|2608974_2609613_-	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	3.2e-50	48.8
WP_023787834.1|2609634_2610225_-|tail	phage tail tape measure protein	A0A0M7QE17	Escherichia_phage	9.9e-06	70.0
WP_081717721.1|2610234_2610408_-|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_023787836.1|2610407_2610782_-	gene transfer agent family protein	NA	NA	NA	NA
WP_023787837.1|2610798_2611212_-|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_023787838.1|2611231_2611642_-	DUF3168 domain-containing protein	A0A2H4JF41	uncultured_Caudovirales_phage	1.3e-09	32.1
WP_041318607.1|2611824_2612130_-|head	phage head closure protein	NA	NA	NA	NA
WP_023787841.1|2612150_2612741_-|head,tail	phage head-tail connector protein	A0A0F7L420	uncultured_marine_virus	2.5e-17	34.0
WP_041318612.1|2612942_2614187_-|capsid	phage major capsid protein	Q3HQT0	Burkholderia_phage	6.6e-76	38.6
WP_023787843.1|2614221_2614941_-|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	2.9e-36	47.7
WP_023787844.1|2615007_2616276_-|portal	phage portal protein	W8ECU7	Geobacillus_phage	4.5e-72	39.7
WP_023787845.1|2616303_2617656_-	DNA-packaging protein	A0A0K1LMR9	Caulobacter_phage	2.3e-66	39.6