CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007028	Thermocrinis ruber strain DSM 23557 chromosome, complete genome	9 crisprs	csa3,TnpB_regular.1,DinG,cmr1gr7,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,csx1,cas7,cas8b2,cas3,cas4,cas1,cas2,cas6,cas5,cas8b1,cas14j,DEDDh	0	2	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007028_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007028_1

1484-1577

Unclear

Consensus_repeat	Method
CTAAAACTGAAGAAGTGTTAGAGGA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP007028_1

>merge|NZ_CP007028|1|1484-1577|CRISPRCasFinder
CTAAAACTGAAGAAGTGTTAGAGGAAACCATGAAGCTTACAGAAGAGTCCAATAGCTTGGAGGAAGAGACTAAAACTGAAGAGGTGTTAGAGGA

>NZ_CP007028|1|1|1484-1577|CRISPRCasFinder
CTAAAACTGAAGAAGTGTTAGAGGA	AACCATGAAGCTTACAGAAGAGTCCAATAGCTTGGAGGAAGAGA
CTAAAACTGAAGAGGTGTTAGAGGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007028.1\|WP_025305241.1\|7071_7722_-\|DNA/RNA-nuclease-SfsA	unknown	unknown	gnl\|CDD\|224406
NZ_CP007028.1\|WP_025305243.1\|10235_10505_+\|flagellar-biosynthesis-anti-sigma-factor-FlgM	unknown	unknown	gnl\|CDD\|274802
NZ_CP007028.1\|WP_025305235.1\|2327_3179_+\|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|237820
NZ_CP007028.1\|WP_025305238.1\|5342_5663_+\|divalent-cation-tolerance-protein-CutA	unknown	unknown	gnl\|CDD\|376987
NZ_CP007028.1\|WP_025305234.1\|1597_2335_+\|twin-arginine-translocase-subunit-TatC	unknown	unknown	gnl\|CDD\|376413
NZ_CP007028.1\|WP_025305232.1\|60_1275_+\|chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl\|CDD\|234667
NZ_CP007028.1\|WP_025305236.1\|3164_4301_-\|acetoin-utilization-protein-AcuC	unknown	unknown	gnl\|CDD\|212520
NZ_CP007028.1\|WP_038532303.1\|4294_5323_-\|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|223286
NZ_CP007028.1\|WP_025305240.1\|6221_7079_-\|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	unknown	unknown	gnl\|CDD\|260116
NZ_CP007028.1\|WP_025305242.1\|7839_10188_-\|ATP-dependent-DNA-helicase-RecG	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236794
NZ_CP007028.1\|WP_025305239.1\|5631_6225_-\|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl\|CDD\|235552

Protein	Function_ID	Function_description	E-value
NZ_CP007028.1\|WP_025305241.1\|7071_7722_-\|DNA/RNA-nuclease-SfsA	gnl\|CDD\|224406	COG1489, SfsA, DNA-binding protein, stimulates sugar fermentation [General function prediction only].	1.24414e-66
NZ_CP007028.1\|WP_025305243.1\|10235_10505_+\|flagellar-biosynthesis-anti-sigma-factor-FlgM	gnl\|CDD\|274802	TIGR03824, FlgM_jcvi, flagellar biosynthesis anti-sigma factor FlgM. FlgM interacts with and inhibits the alternative sigma factor sigma(28) FliA. The C-terminus of FlgM contains the sigma(28)-binding domain.	0.000357734
NZ_CP007028.1\|WP_025305235.1\|2327_3179_+\|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein	gnl\|CDD\|237820	PRK14806, PRK14806, bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	3.91332e-93
NZ_CP007028.1\|WP_025305238.1\|5342_5663_+\|divalent-cation-tolerance-protein-CutA	gnl\|CDD\|376987	pfam03091, CutA1, CutA1 divalent ion tolerance protein. Several gene loci with a possible involvement in cellular tolerance to copper have been identified. One such locus in eubacteria and archaebacteria, cutA, is thought to be involved in cellular tolerance to a wide variety of divalent cations other than copper. The cutA locus consists of two operons, of one and two genes. The CutA1 protein is a cytoplasmic protein, encoded by the single-gene operon and has been linked to divalent cation tolerance. It has no recognized structural motifs. This family also contains putative proteins from eukaryotes (human and Drosophila).	3.76569e-45
NZ_CP007028.1\|WP_025305234.1\|1597_2335_+\|twin-arginine-translocase-subunit-TatC	gnl\|CDD\|376413	pfam00902, TatC, Sec-independent protein translocase protein (TatC). The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane. It is structurally and mechanistically similar to the Delta pH-driven thylakoidal protein import pathway. A functional Tat system or Delta pH-dependent pathway requires three integral membrane proteins: TatA/Tha4, TatB/Hcf106 and TatC/cpTatC. The TatC protein is essential for the function of both pathways. It might be involved in twin-arginine signal peptide recognition, protein translocation and proton translocation. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N- and C-termini of TatC or cpTatC are exposed to the cytoplasmic or stromal face of the membrane. The cytoplasmic N-terminus and the first cytoplasmic loop region of the Escherichia coli TatC protein are essential for protein export. At least two TatC molecules co-exist within each Tat translocon.	2.61928e-73
NZ_CP007028.1\|WP_025305232.1\|60_1275_+\|chromosomal-replication-initiator-protein-DnaA	gnl\|CDD\|234667	PRK00149, dnaA, chromosomal replication initiator protein DnaA.	8.52926e-118
NZ_CP007028.1\|WP_025305236.1\|3164_4301_-\|acetoin-utilization-protein-AcuC	gnl\|CDD\|212520	cd09994, HDAC_AcuC_like, Class I histone deacetylase AcuC (Acetoin utilization protein)-like enzymes. AcuC (Acetoin utilization protein) is a class I deacetylase found only in bacteria and is involved in post-translational control of the acetyl-coenzyme A synthetase (AcsA). Deacetylase AcuC works in coordination with deacetylase SrtN (class III), possibly to maintain AcsA in active (deacetylated) form and let the cell grow under low concentration of acetate. B. subtilis AcuC is a member of operon acuABC; this operon is repressed by the presence of glucose and does not show induction by acetoin; acetoin is a bacterial fermentation product that can be converted to acetate via the butanediol cycle in absence of other carbon sources. Inactivation of AcuC leads to slower growth and lower cell yield under low-acetate conditions in Bacillus subtilis. In general, Class I histone deacetylases (HDACs) are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues in histone amino termini to yield a deacetylated histone (EC 3.5.1.98). Enzymes belonging to this group participate in regulation of a number of processes through protein (mostly different histones) modification (deacetylation). Class I histone deacetylases in general act via the formation of large multiprotein complexes. Members of this class are involved in cell cycle regulation, DNA damage response, embryonic development, cytokine signaling important for immune response and in posttranslational control of the acetyl coenzyme A synthetase.	4.27899e-142
NZ_CP007028.1\|WP_038532303.1\|4294_5323_-\|ribonucleotide-diphosphate-reductase-subunit-beta	gnl\|CDD\|223286	COG0208, NrdF, Ribonucleotide reductase, beta subunit [Nucleotide transport and metabolism].	6.44776e-112
NZ_CP007028.1\|WP_025305240.1\|6221_7079_-\|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	gnl\|CDD\|260116	cd13944, lytB_ispH, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. The 4-hydroxy-3-methylbut-2-enyl diphosphate (HMBPP) reductase (called lytB or ispH) is the terminal enzyme of the mevalonate-independent 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway, one of the two metabolic routes for isoprenoid biosynthesis. The MEP pathway is essential in many eubacteria, plants, and the malaria parasite. LytB converts HMBPP into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).	2.25653e-147
NZ_CP007028.1\|WP_025305242.1\|7839_10188_-\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NZ_CP007028.1\|WP_025305239.1\|5631_6225_-\|aminodeoxychorismate/anthranilate-synthase-component-II	gnl\|CDD\|235552	PRK05670, PRK05670, anthranilate synthase component II; Provisional.	8.41383e-123

>NZ_CP007028.1|WP_025305232.1|60_1275_+|chromosomal-replication-initiator-protein-DnaA
MEGGSFLNLIESLDKFAVGIFRQFLIREDTDKILILTPNEEYKRWAIAYLSTRLKGFGKKVVVECEGERKEQKEIESPKDNLLDKYTFENFVVGPSNELAYKVCLEVTKNPGKLFNPLFIYGRSGLGKTHLLHAIGNQLKARYRVLYIPLMDFSDSMVKAFKENRVEEFRERFFNLDVLLLDDVQFLVGKERTQIELFRIYEKLQAEEKQIVLVSDRHPRDLKDVSERLVSRFESGLIIEIGLDEETKRRIIKQKLILYGLPLDQETIDYVFENTGYNVREIEGFVKTLKVSGIKRLPKSEELDKEKKVQLIINTVAKGFKLNPELLKKDTKERRMINARHIAMFLCKTILNLPYSQIGEFFGKKDHTAVMYAVKKVEQRCREDRKFMYMVSFFEKSIRKSLGL
>NZ_CP007028.1|WP_025305234.1|1597_2335_+|twin-arginine-translocase-subunit-TatC
MPLTEHLRELRQRLIKSVVAFLVATGAAFYLAQYIFEVLKEPVKRAYPQVQLITLSPTEPLFILIKISVVFGFILSSPVILYQLWKFVEPALYPHEKRLVIPITLFSIILFLLGVSFAYFLVMPIALKFLIGIGFSQLQATPYLSVNLYVSFLLKMIVGFGLAFQLPIVLYLLQRAGIVSEQQLKAFRKYFIVIAFVIGAFIAPDATTQVLMAIPLILLYEISLIFGKLGRRKKETSIEQVKENV
>NZ_CP007028.1|WP_025305235.1|2327_3179_+|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein
MFKRVAIVGVGFMGGSFSLAVKSRLGCSTFGMDINPEAIKRGKELGVIDEGSTQMLALRDFEPDLVVLAVPVGAFEQVARGLKEVLDEKVLITDLGSVKGRLVYMMEDFFGGYFVGGHPIAGTEKSGVQYSNPELFKNKRVVLTPTQRTDRLALQKVKFMWERLDAFVEFMDPFVHDVVFGAVSHLPHAVAFALMDAMEKLSKKTNIDLFLYPGGGFKDFTRIAASDPVMWRDIFLENRENLLWAIEEFIQSLEKLKGLIENEKKEELIEYLQRAREHRLRID
>NZ_CP007028.1|WP_025305236.1|3164_4301_-|acetoin-utilization-protein-AcuC
MVKHSAKLIASYSYRKLRYTPNHPLRIPRVSLLLEFLKAMELLEDGEWVESRPAQWEELTLFHEEEYLLALQRADQEGRVSKEVRERFHIGTIENPVSPAMWKGSLLATGSSVQAVQLFLEGNLAFNPAGGMHHAYPSRANGFCFINDPAVAINYLKQKGYRKILYIDLDAHHCDGVQDGFYEDDEVFVLSLHQSPEYAFPFNRGFLEERGRGKGKGYNLNIPLPKGINDSEFLYALEKAIDIVKDIFEPEVYVLQLGTDTLKEDYLSKFELSNWGFLRAFRLVKDAFGEGIYLGGGGYHPIALARAWALIWCELSQREIPKFLTPKAKEVLLKVDFEEFEEEDKSYMFERLLDEPREGEVRQEVKDILEKARALVYS
>NZ_CP007028.1|WP_038532303.1|4294_5323_-|ribonucleotide-diphosphate-reductase-subunit-beta
MERVLIFNPEGDREPSKRKIVFGNPTNIMELNNVKYQWAFDLYKTMGFTNFWIPEEIPMLEDKKQYERLLSEHERRAYELVISFLIALDSYQVNMLKEFARYLTAPELVMAITSQEFQEALHSYSYQFILESVVEPTKADEIYNYWRQDEKLMERNKVVAEVYNEFIKNPTEENFIKAVFGNYVLESLYFYSGFAFFYTLGRQGKMLNTVQQIKYINRDELTHVTLFRNIINTLKEEQPDLFTPEINKWVYEFFKFATEKEIEWGKYVTNNQILGLNDKLIERYIKYLANLRLTQIGYEPLYPEVTENPMKWIDQFRTINDTKTDFFQAKPQTYAKRSELKW
>NZ_CP007028.1|WP_025305238.1|5342_5663_+|divalent-cation-tolerance-protein-CutA
MDWKHVVVLITIPTDKGLELADYIVKNKLGACVNVVPEVNSIYWWKGNIERDKESLLMIKTSLQKLEELIKEVKSVHPYTVPEIIALPILGGNEDYLRWIDDSLGL
>NZ_CP007028.1|WP_025305239.1|5631_6225_-|aminodeoxychorismate/anthranilate-synthase-component-II
MKVFMIDNYDSFTYNLVQYFQILGAEVVVKRNDQTTIEEIRELYPDAIVISPGPCSPKEAGISVKVVQELYRDYPILGVCLGHQSIGYAFGANIVRAKRLMHGKTSLITHTGEGIFSGIPNPFTAVRYHSLVIDERTLPPFLKVTARSEEDDEVMAIQHTEYPVFGVQFHPESVLSEAGMDILKNFLTIAQGYRLSI
>NZ_CP007028.1|WP_025305240.1|6221_7079_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase
MAEIIVAPHAGFCFGVRRAIALAEKVSAEKGGKRIWSMGPLIHNPQEVQRLRGLGIEVMASEEDAKEGDTVIIRSHGIPPQKERELLQKGLRLVDATCPYVKAVHQAVEKLVQEGYFVVLVGERDHPEVIGTLGYLQEAGGTGVVVEKKEDLEKLKNLERVGVVAQTTQSEQFFKEVVGELALWVKELKVINTICNATSERQEDVYELAGKVDVMIIVGGKNSGNTRRLYQISSSLNPRSYHVETAEELKPEWFVGVQRVGITAGASTPDWIIEQVKSKIQELLS
>NZ_CP007028.1|WP_025305241.1|7071_7722_-|DNA/RNA-nuclease-SfsA
MKFPELIPAKFLRRLNRFVGEVSIEGKRVFAHIRNTGRLTELLKPGNTVFLKEKNSGKYPFEVLLVDMGSSLVCIDSTITPKLYAEFLNLPVRFEPKFEKHRFDLMYDSRVVETKSVNLVEDGVALFPDAPTERGRRHIQKLIELSEQGFEPQLIFVVQREDALVFSPNYKVDKPFSEAVQEFYNRGLTVKAFLCNVSLREISISREIEVIFLKDG
>NZ_CP007028.1|WP_025305242.1|7839_10188_-|ATP-dependent-DNA-helicase-RecG
MDSVEKAKKLIEELKENNHLKLRRSFGVGLYLFNLLKNRLSNSHLELLKKFDSMPFPKKVAILQEIEQALNKEELVPTVSFDGYPKKPIEKFFIPIESLKILDPKEKKLLKSLNIKDLYSALWYVPVRYEDRRLNTSIKTSIPGKAVALKVKVVESSWEPDAKYPISVLCEDGTSYLSLKYRFKDKRALLSFKKGTELIVYGKLMEYKGEKYMVHPELLKEEEAGKVLPFYNIRVKSAESMSAKLRHRKVRQAIQKLLEYLRYMPEYLPEELLKKHNLYRLPESLYFLHAPHQWDERLNTWDTPAHHRLIYEDLLLFQLALQLKRREIKSLRAPRLLRAEEHIQEFLRSLPFGLTQAQLRVLKEILEDVKQETPMNRLLQGDVGSGKTVVAMAISYAFAKEGYQSAIMVPTEILAYQHYENFKRFLEPLGVKVGLLTSSVKTAQRRSLLRHIREGNIQVVVGTHALIQEGVSFKSLGFAVVDEQHRFGVLQRKRLLEKSEEFFPHLLVMSATPIPRTLALSLYGDLDISIIDQMPAGRKPVITRLFFESEMEKVLKFIKEELQKGHKAYVIYPVIEDSPKLELKSAVKEFERWKALFPDRKVLLLHGRLKDEEKKRVMEEFKQDGDILVSTTVVEVGVDVPDATVMVIESAHRFGLSQLHQLRGRVGRSQLQSFCFLVVPDQMRYDQESLKRLKVLVQTNDGFKIAEEDLKMRGPGELLGESQSGYFGFWVANLQRERDRHFLEVCKKDAQELLEKDPYLERYPELRQVLFYRYSEGIIAPP
>NZ_CP007028.1|WP_025305243.1|10235_10505_+|flagellar-biosynthesis-anti-sigma-factor-FlgM
MIERVDLWNLVNNILEQERKSKEKPAEVKEQEAVKVELSEVAKSRPQPDLSELESKVSEIKAKLERGEYKVEPEKIFEGLSKYLSSSDR

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Crispr_ID: NZ_CP007028_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007028_2

95670-96909

Orphan

Consensus_repeat	Method
GCTTTCAACTCCACACGGTACATTAGGAAC	PILER-CR
CTTTCAACTCCACACGGTACATTAGGAAC	CRISPRCasFinder
CTTTCAACTCCACACGGTACATTAGGAAC	CRT
CTTTCAACTCCACACGGTACATTAGGAAC	PILER-CR

18 spacers

The CRISPR arrays of NZ_CP007028_2

>merge|NZ_CP007028|2|95670-96909|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
CTTTCAACTCCACACGGTACATTAGGAACGCCCGATAATGCACCCGCACGGCCACCAGCGACCTGCTTTCAACTCCACACGGTACATTAGGAACTAACCTTCGTTTAGGTGAGGCTTTTGTGGCGTTTCTGAGCTTTCAACTCCACACGGTACATTAGGAACCTAACGGACAAGGCAGAAGTCTTATCCACCATCCTACTTTCAACTCCACACGGTACATTAGGAACAAAGCTTCTTTTTGTGTGCTACGATGATAACAAAGCTTGCTTTCAACTCCACACGGTACATTAGGAACAAAGCTTCTTTTTGTGTGCTACGATGATAACAAAGCTTGCTTTCAACTCCACACGGTACATTAGGAACAAAAAGTAGTCGTAAGTAGAGGCTTGTACGGGCGTGATTCTTTCAACTCCACACGGTACATTAGGAACTTAGAGTTCTTCAGGGCGTTAGCATTGATACTGGTTCCTTTCAACTCCACACGGTACATTAGGAACATAGAAGAGGTGGGCAAGGTTCAAGACAAAGACGCACTTTCAACTCCACACGGTACATTAGGAACGAAAAGACCGCAAGAGTAAGAGTGCAAATGCCAGACCTTGACTTTCAACTCCACACGGTACATTAGGAACCGGTATTCTGTAAGCTTTATATTGCAGTAAATCACAACTTTCAACTCCACACGGTACATTAGGAACCATACGCCCGCAAAGTTGCAATAGACGAGACAGGGATCTTTCAACTCCACACGGTACATTAGGAACCGGTATTCTGTAAGCTTTATATTGCAGTAAATCACAACTTTCAACTCCACACGGTACATTAGGAACCTACGACGAGAAGGGCGCCTTCAGACTTGAGGAGTTTCTGACTTTCAACTCCACACGGTACATTAGGAACCCCAGCAATGTGATGAGAGTCAGGTTTTTAACTTAGTTTACTTTCAACTCCACACGGTACATTAGGAACCCTATTATTGGATGGACATTCCCAGCTATATGGAAATATGCGGCTTTCAACTCCACACGGTACATTAGGAACAGTTCCATACTTTGCTCCGTTTGAATTAGGTTATACAACTTTCAACTCCACACGGTACATTAGGAACATACTCAACCCAAGCCATCCCACACCCTCAAACAACCACTTTCAACTCCACACGGTACATTAGGAACATCTCAAAATAGCTAAGAACCTAAACCAACGGAATACTTTCAACTCCACACGGTACATTAGGAAC

>NZ_CP007028|2|1|95670-95831|PILER-CR
CTTTCAACTCCACACGGTACATTAGGAACG	CCCGATAATGCACCCGCACGGCCACCAGCGACCTG
CTTTCAACTCCACACGGTACATTAGGAACT	AACCTTCGTTTAGGTGAGGCTTTTGTGGCGTTTCTGAG
CTTTCAACTCCACACGGTACATTAGGAACCTAACGGACAAGGCAGAAGTCTTATCCACCATCCTACTTTCAACTCCACACGGTACATTAGGAACAAAGCTTCTTTTTGTGTGCTACGATGATAACAAAGCTTGCTTTCAACTCCACACGGTACATTAGGAACAAAGCTTCTTTTTGTGTGCTACGATGATAACAAAGCTTGCTTTCAACTCCACACGGTACATTAGGAAC	AAAAAGTAGTCGTAAGTAGAGGCTTGTACGGGCGTGATT
CTTTCAACTCCACACGGTACATTAGGAAC	TTAGAGTTCTTCAGGGCGTTAGCATTGATACTGGTTC
CTTTCAACTCCACACGGTACATTAGGAAC	ATAGAAGAGGTGGGCAAGGTTCAAGACAAAGACGCA
CTTTCAACTCCACACGGTACATTAGGAAC	GAAAAGACCGCAAGAGTAAGAGTGCAAATGCCAGACCTTGA
CTTTCAACTCCACACGGTACATTAGGAAC	CGGTATTCTGTAAGCTTTATATTGCAGTAAATCACAA
CTTTCAACTCCACACGGTACATTAGGAAC	CATACGCCCGCAAAGTTGCAATAGACGAGACAGGGAT
CTTTCAACTCCACACGGTACATTAGGAAC	CGGTATTCTGTAAGCTTTATATTGCAGTAAATCACAA
CTTTCAACTCCACACGGTACATTAGGAAC	CTACGACGAGAAGGGCGCCTTCAGACTTGAGGAGTTTCTGA
CTTTCAACTCCACACGGTACATTAGGAAC	CCCAGCAATGTGATGAGAGTCAGGTTTTTAACTTAGTTTA
CTTTCAACTCCACACGGTACATTAGGAAC	CCTATTATTGGATGGACATTCCCAGCTATATGGAAATATGCGG
CTTTCAACTCCACACGGTACATTAGGAAC	AGTTCCATACTTTGCTCCGTTTGAATTAGGTTATACAA
CTTTCAACTCCACACGGTACATTAGGAAC	ATACTCAACCCAAGCCATCCCACACCCTCAAACAACCA
CTTTCAACTCCACACGGTACATTAGGAAC	ATCTCAAAATAGCTAAGAACCTAAACCAACGGAATA


>NZ_CP007028|2|2|95670-96909|CRISPRCasFinder
CTTTCAACTCCACACGGTACATTAGGAAC	GCCCGATAATGCACCCGCACGGCCACCAGCGACCTG
CTTTCAACTCCACACGGTACATTAGGAAC	TAACCTTCGTTTAGGTGAGGCTTTTGTGGCGTTTCTGAG
CTTTCAACTCCACACGGTACATTAGGAAC	CTAACGGACAAGGCAGAAGTCTTATCCACCATCCTA
CTTTCAACTCCACACGGTACATTAGGAAC	AAAGCTTCTTTTTGTGTGCTACGATGATAACAAAGCTTG
CTTTCAACTCCACACGGTACATTAGGAAC	AAAGCTTCTTTTTGTGTGCTACGATGATAACAAAGCTTG
CTTTCAACTCCACACGGTACATTAGGAAC	AAAAAGTAGTCGTAAGTAGAGGCTTGTACGGGCGTGATT
CTTTCAACTCCACACGGTACATTAGGAAC	TTAGAGTTCTTCAGGGCGTTAGCATTGATACTGGTTC
CTTTCAACTCCACACGGTACATTAGGAAC	ATAGAAGAGGTGGGCAAGGTTCAAGACAAAGACGCA
CTTTCAACTCCACACGGTACATTAGGAAC	GAAAAGACCGCAAGAGTAAGAGTGCAAATGCCAGACCTTGA
CTTTCAACTCCACACGGTACATTAGGAAC	CGGTATTCTGTAAGCTTTATATTGCAGTAAATCACAA
CTTTCAACTCCACACGGTACATTAGGAAC	CATACGCCCGCAAAGTTGCAATAGACGAGACAGGGAT
CTTTCAACTCCACACGGTACATTAGGAAC	CGGTATTCTGTAAGCTTTATATTGCAGTAAATCACAA
CTTTCAACTCCACACGGTACATTAGGAAC	CTACGACGAGAAGGGCGCCTTCAGACTTGAGGAGTTTCTGA
CTTTCAACTCCACACGGTACATTAGGAAC	CCCAGCAATGTGATGAGAGTCAGGTTTTTAACTTAGTTTA
CTTTCAACTCCACACGGTACATTAGGAAC	CCTATTATTGGATGGACATTCCCAGCTATATGGAAATATGCGG
CTTTCAACTCCACACGGTACATTAGGAAC	AGTTCCATACTTTGCTCCGTTTGAATTAGGTTATACAA
CTTTCAACTCCACACGGTACATTAGGAAC	ATACTCAACCCAAGCCATCCCACACCCTCAAACAACCA
CTTTCAACTCCACACGGTACATTAGGAAC	ATCTCAAAATAGCTAAGAACCTAAACCAACGGAATA
CTTTCAACTCCACACGGTACATTAGGAAC

>NZ_CP007028|2|1|95670-96909|CRT
CTTTCAACTCCACACGGTACATTAGGAAC	GCCCGATAATGCACCCGCACGGCCACCAGCGACCTG
CTTTCAACTCCACACGGTACATTAGGAAC	TAACCTTCGTTTAGGTGAGGCTTTTGTGGCGTTTCTGAG
CTTTCAACTCCACACGGTACATTAGGAAC	CTAACGGACAAGGCAGAAGTCTTATCCACCATCCTA
CTTTCAACTCCACACGGTACATTAGGAAC	AAAGCTTCTTTTTGTGTGCTACGATGATAACAAAGCTTG
CTTTCAACTCCACACGGTACATTAGGAAC	AAAGCTTCTTTTTGTGTGCTACGATGATAACAAAGCTTG
CTTTCAACTCCACACGGTACATTAGGAAC	AAAAAGTAGTCGTAAGTAGAGGCTTGTACGGGCGTGATT
CTTTCAACTCCACACGGTACATTAGGAAC	TTAGAGTTCTTCAGGGCGTTAGCATTGATACTGGTTC
CTTTCAACTCCACACGGTACATTAGGAAC	ATAGAAGAGGTGGGCAAGGTTCAAGACAAAGACGCA
CTTTCAACTCCACACGGTACATTAGGAAC	GAAAAGACCGCAAGAGTAAGAGTGCAAATGCCAGACCTTGA
CTTTCAACTCCACACGGTACATTAGGAAC	CGGTATTCTGTAAGCTTTATATTGCAGTAAATCACAA
CTTTCAACTCCACACGGTACATTAGGAAC	CATACGCCCGCAAAGTTGCAATAGACGAGACAGGGAT
CTTTCAACTCCACACGGTACATTAGGAAC	CGGTATTCTGTAAGCTTTATATTGCAGTAAATCACAA
CTTTCAACTCCACACGGTACATTAGGAAC	CTACGACGAGAAGGGCGCCTTCAGACTTGAGGAGTTTCTGA
CTTTCAACTCCACACGGTACATTAGGAAC	CCCAGCAATGTGATGAGAGTCAGGTTTTTAACTTAGTTTA
CTTTCAACTCCACACGGTACATTAGGAAC	CCTATTATTGGATGGACATTCCCAGCTATATGGAAATATGCGG
CTTTCAACTCCACACGGTACATTAGGAAC	AGTTCCATACTTTGCTCCGTTTGAATTAGGTTATACAA
CTTTCAACTCCACACGGTACATTAGGAAC	ATACTCAACCCAAGCCATCCCACACCCTCAAACAACCA
CTTTCAACTCCACACGGTACATTAGGAAC	ATCTCAAAATAGCTAAGAACCTAAACCAACGGAATA
CTTTCAACTCCACACGGTACATTAGGAAC

>NZ_CP007028|2|2|96004-96909|PILER-CR
	CCCGATAATGCACCCGCACGGCCACCAGCGACCTG
CTTTCAACTCCACACGGTACATTAGGAACT	AACCTTCGTTTAGGTGAGGCTTTTGTGGCGTTTCTGAG
CTTTCAACTCCACACGGTACATTAGGAACCTAACGGACAAGGCAGAAGTCTTATCCACCATCCTACTTTCAACTCCACACGGTACATTAGGAACAAAGCTTCTTTTTGTGTGCTACGATGATAACAAAGCTTGCTTTCAACTCCACACGGTACATTAGGAACAAAGCTTCTTTTTGTGTGCTACGATGATAACAAAGCTTGCTTTCAACTCCACACGGTACATTAGGAAC	AAAAAGTAGTCGTAAGTAGAGGCTTGTACGGGCGTGATT
CTTTCAACTCCACACGGTACATTAGGAAC	TTAGAGTTCTTCAGGGCGTTAGCATTGATACTGGTTC
CTTTCAACTCCACACGGTACATTAGGAAC	ATAGAAGAGGTGGGCAAGGTTCAAGACAAAGACGCA
CTTTCAACTCCACACGGTACATTAGGAAC	GAAAAGACCGCAAGAGTAAGAGTGCAAATGCCAGACCTTGA
CTTTCAACTCCACACGGTACATTAGGAAC	CGGTATTCTGTAAGCTTTATATTGCAGTAAATCACAA
CTTTCAACTCCACACGGTACATTAGGAAC	CATACGCCCGCAAAGTTGCAATAGACGAGACAGGGAT
CTTTCAACTCCACACGGTACATTAGGAAC	CGGTATTCTGTAAGCTTTATATTGCAGTAAATCACAA
CTTTCAACTCCACACGGTACATTAGGAAC	CTACGACGAGAAGGGCGCCTTCAGACTTGAGGAGTTTCTGA
CTTTCAACTCCACACGGTACATTAGGAAC	CCCAGCAATGTGATGAGAGTCAGGTTTTTAACTTAGTTTA
CTTTCAACTCCACACGGTACATTAGGAAC	CCTATTATTGGATGGACATTCCCAGCTATATGGAAATATGCGG
CTTTCAACTCCACACGGTACATTAGGAAC	AGTTCCATACTTTGCTCCGTTTGAATTAGGTTATACAA
CTTTCAACTCCACACGGTACATTAGGAAC	ATACTCAACCCAAGCCATCCCACACCCTCAAACAACCA
CTTTCAACTCCACACGGTACATTAGGAAC	ATCTCAAAATAGCTAAGAACCTAAACCAACGGAATA
CTTTCAACTCCACACGGTACATTAGGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007028.1\|WP_025305326.1\|89641_90943_-\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
NZ_CP007028.1\|WP_025305340.1\|104147_105113_-\|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|187563
NZ_CP007028.1\|WP_025305334.1\|99826_100927_-\|PilT/PilU-family-type-4a-pilus-ATPase	unknown	unknown	gnl\|CDD\|225364
NZ_CP007028.1\|WP_025305336.1\|101955_102240_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl\|CDD\|178810
NZ_CP007028.1\|WP_038531922.1\|83915_84554_-\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|237310
NZ_CP007028.1\|WP_025305328.1\|91472_92672_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235298
NZ_CP007028.1\|WP_038531930.1\|100895_101930_-\|recombinase-RecA	unknown	unknown	gnl\|CDD\|236476
NZ_CP007028.1\|WP_025305330.1\|93458_95321_-\|1-deoxy-D-xylulose-5-phosphate-synthase	unknown	unknown	gnl\|CDD\|235470
NZ_CP007028.1\|WP_038531928.1\|99182_99827_-\|(d)CMP-kinase	unknown	unknown	gnl\|CDD\|234579
NZ_CP007028.1\|WP_025305339.1\|103164_104151_-\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|224012
NZ_CP007028.1\|WP_051402167.1\|87001_88999_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|224369
NZ_CP007028.1\|WP_038531926.1\|98496_99186_-\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|381680
NZ_CP007028.1\|WP_025305338.1\|102628_103117_-\|4-vinyl-reductase	unknown	unknown	gnl\|CDD\|224633
NZ_CP007028.1\|WP_025305323.1\|84532_86833_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|180831
NZ_CP007028.1\|WP_025305332.1\|97328_98513_+\|TRC40/GET3/ArsA-family-transport-energizing-ATPase	unknown	unknown	gnl\|CDD\|367057
NZ_CP007028.1\|WP_025305337.1\|102233_102632_-\|YjbQ-family-protein	unknown	unknown	gnl\|CDD\|376651
NZ_CP007028.1\|WP_025305327.1\|90972_91476_+\|archaemetzincin-family-Zn-dependent-metalloprotease	unknown	unknown	gnl\|CDD\|213029
NZ_CP007028.1\|WP_051402146.1\|95381_95609_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025305325.1\|88976_89645_-\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|238244
NZ_CP007028.1\|WP_025305329.1\|92692_93448_-\|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl\|CDD\|307628

Protein	Function_ID	Function_description	E-value
NZ_CP007028.1\|WP_025305326.1\|89641_90943_-\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NZ_CP007028.1\|WP_025305340.1\|104147_105113_-\|GDP-mannose-4,6-dehydratase	gnl\|CDD\|187563	cd05253, UDP_GE_SDE_e, UDP glucuronic acid epimerase, extended (e) SDRs. This subgroup contains UDP-D-glucuronic acid 4-epimerase, an extended SDR, which catalyzes the conversion of UDP-alpha-D-glucuronic acid to UDP-alpha-D-galacturonic acid. This group has the SDR's canonical catalytic tetrad and the TGxxGxxG NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.05568e-177
NZ_CP007028.1\|WP_025305334.1\|99826_100927_-\|PilT/PilU-family-type-4a-pilus-ATPase	gnl\|CDD\|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	7.55878e-152
NZ_CP007028.1\|WP_025305336.1\|101955_102240_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl\|CDD\|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	3.34264e-28
NZ_CP007028.1\|WP_038531922.1\|83915_84554_-\|HAD-IA-family-hydrolase	gnl\|CDD\|237310	PRK13222, PRK13222, N-acetylmuramic acid 6-phosphate phosphatase MupP.	7.41932e-63
NZ_CP007028.1\|WP_025305328.1\|91472_92672_-\|methionine-adenosyltransferase	gnl\|CDD\|235298	PRK04439, PRK04439, methionine adenosyltransferase.	0
NZ_CP007028.1\|WP_038531930.1\|100895_101930_-\|recombinase-RecA	gnl\|CDD\|236476	PRK09354, recA, recombinase A; Provisional.	0
NZ_CP007028.1\|WP_025305330.1\|93458_95321_-\|1-deoxy-D-xylulose-5-phosphate-synthase	gnl\|CDD\|235470	PRK05444, PRK05444, 1-deoxy-D-xylulose-5-phosphate synthase; Provisional.	0
NZ_CP007028.1\|WP_038531928.1\|99182_99827_-\|(d)CMP-kinase	gnl\|CDD\|234579	PRK00023, cmk, (d)CMP kinase.	1.96126e-84
NZ_CP007028.1\|WP_025305339.1\|103164_104151_-\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|224012	COG1087, GalE, UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane].	0
NZ_CP007028.1\|WP_051402167.1\|87001_88999_+\|LPS-assembly-protein-LptD	gnl\|CDD\|224369	COG1452, Imp, Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane].	2.64779e-45
NZ_CP007028.1\|WP_038531926.1\|98496_99186_-\|uracil-DNA-glycosylase	gnl\|CDD\|381680	cd10030, UDG-F4_TTUDGA_SPO1dp_like, Uracil DNA glycosylase family 4, includes Thermotoga maritima TTUDGA, Bacillus phage SPO1 DNA polymerase, and similar proteins. Uracil DNA glycosylase family 4 includes Thermotoga maritima TTUDGA, a robust uracil DNA glycosylase that shares narrow substrate specificity and high catalytic efficiency with family 1, acting on double-stranded and single-stranded uracil-containing DNA. Members of this family possess four conserved cysteine residues required to coordinate the [4Fe-4S] iron-sulfur cluster. This family also includes the N-terminal domain of Bacillus phage SPO1 DNA polymerase. Bacteriophage SPO1 is one of a group of large, lytic, tailed bacteriophages of Bacillus subtilis, and contains hydroxymethyluracil (hmUra) in place of thymine in their DNA. It has been speculated that this UDG domain may help discriminate between hmUra containing SPO1 DNA and thymine-containing host DNA. Uracil-DNA glycosylases (UDGs) initiate repair of uracils in DNA. Uracil in DNA can arise as a result of mis-incorporation of dUMP residues by DNA polymerase or via deamination of cytosine. Uracil in DNA mispaired with guanine is one of the major pro-mutagenic events, causing G:C->A:T mutations. Thus, UDG is an essential enzyme for maintaining the integrity of genetic information. UDGs have been classified into various families on the basis of their substrate specificity, conserved motifs, and structural similarities. Although these families demonstrate different substrate specificities, often the function of one enzyme can be complemented by the other.	4.71931e-88
NZ_CP007028.1\|WP_025305338.1\|102628_103117_-\|4-vinyl-reductase	gnl\|CDD\|224633	COG1719, COG1719, Predicted hydrocarbon binding protein (contains V4R domain) [General function prediction only].	3.56766e-22
NZ_CP007028.1\|WP_025305323.1\|84532_86833_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|180831	PRK07088, PRK07088, ribonucleoside-diphosphate reductase subunit alpha.	0
NZ_CP007028.1\|WP_025305332.1\|97328_98513_+\|TRC40/GET3/ArsA-family-transport-energizing-ATPase	gnl\|CDD\|367057	pfam02374, ArsA_ATPase, Anion-transporting ATPase. This Pfam family represents a conserved domain, which is sometimes repeated, in an anion-transporting ATPase. The ATPase is involved in the removal of arsenate, antimonite, and arsenate from the cell.	3.31495e-114
NZ_CP007028.1\|WP_025305337.1\|102233_102632_-\|YjbQ-family-protein	gnl\|CDD\|376651	pfam01894, UPF0047, Uncharacterized protein family UPF0047. This family has no known function. The alignment contains a conserved aspartate and histidine that may be functionally important.	1.54088e-64
NZ_CP007028.1\|WP_025305327.1\|90972_91476_+\|archaemetzincin-family-Zn-dependent-metalloprotease	gnl\|CDD\|213029	cd11375, Peptidase_M54, Peptidase family M54, also called archaemetzincins or archaelysins. Peptidase M54 (archaemetzincin or archaelysin) is a zinc-dependent aminopeptidase that contains the consensus zinc-binding sequence HEXXHXXGXXH/D and a conserved Met residue at the active site, and is thus classified as a metzincin. Archaemetzincins, first identified in archaea, are also found in bacteria and eukaryotes, including two human members, archaemetzincin-1 and -2 (AMZ1 and AMZ2). AMZ1 is mainly found in the liver and heart while AMZ2 is primarily expressed in testis and heart; both have been reported to degrade synthetic substrates and peptides. The Peptidase M54 family contains an extended metzincin concensus sequence of HEXXHXXGX3CX4CXMX17CXXC such that a second zinc ion is bound to four cysteines, thus resembling a zinc finger. Phylogenetic analysis of this family reveals a complex evolutionary process involving a series of lateral gene transfer, gene loss and genetic duplication events.	5.38095e-65
NZ_CP007028.1\|WP_025305325.1\|88976_89645_-\|ribulose-phosphate-3-epimerase	gnl\|CDD\|238244	cd00429, RPE, Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose phosphate pathway. In the Calvin cycle Ru5P is phosphorylated by phosphoribulose kinase to ribulose-1,5-bisphosphate, which in turn is used by RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) to incorporate CO2 as the central step in carbohydrate synthesis.	4.52519e-119
NZ_CP007028.1\|WP_025305329.1\|92692_93448_-\|cytochrome-c-biogenesis-protein-CcsA	gnl\|CDD\|307628	pfam01578, Cytochrom_C_asm, Cytochrome C assembly protein. This family consists of various proteins involved in cytochrome c assembly from mitochondria and bacteria; CycK from Rhizobium, CcmC from E. coli and Paracoccus denitrificans and orf240 from wheat mitochondria. The members of this family are probably integral membrane proteins with six predicted transmembrane helices. It has been proposed that members of this family comprise a membrane component of an ABC (ATP binding cassette) transporter complex. It is also proposed that this transporter is necessary for transport of some component needed for cytochrome c assembly. One member CycK contains a putative heme-binding motif, orf240 also contains a putative heme-binding motif and is a proposed ABC transporter with c-type heme as its proposed substrate. However it seems unlikely that all members of this family transport heme nor c-type apocytochromes because CcmC in the putative CcmABC transporter transports neither. CcmF forms a working module with CcmH and CcmI, CcmFHI, and itself is unlikely to bind haem directly.	4.22889e-15

>NZ_CP007028.1|WP_051402146.1|95381_95609_-|hypothetical-protein
MLVLAVGVAFGSDCVPRLSVEEASRQASQYVGRVLSVNLSKNKKGECYYRVRGTEGTAVIDANDGKLLRFYRKRD
>NZ_CP007028.1|WP_025305330.1|93458_95321_-|1-deoxy-D-xylulose-5-phosphate-synthase
MILEKYTGPIDLKYMTYEELEKLAEEVRDYILDVTAKNGGHVAPGLGVVELTIALLRVFDPPKDIIVWDIGHQAYPWKILTDRKDKFPTLRQYGGISGFLRREESPYDAFGAGHSSTSISAGLGFRVAKDLLKRDGYVVMVIGDGAMTAGMAFEALNNAGHLRPNKFIVILNDNEMSISPNVGAISTYLSKIISGRFVQETRQKIKRLVQHLGGPAERFMKLTEEFLKGLISPGVIFEELGFNYIGPINGHDLPALESTLKNVKEIEGPVLLHVYTKKGKGYKPAEKDPVTWHGVAPYKRESGEFIKKPSPPTWTSVFGKAIVKMAEMDEKVVVITPAMKEGSGLVEFAEKFPNRFFDVGIAEQHACTFAGGLAAEGLKPVACYYSTFLQRAYDQVIHDIALQKLHVVFAIDRAGLVGEDGPTHHGVFDLSYLRCIPNMIVCAPKDEQELIDLLYTGLNQNLPFALRYPRGPAYGVPTGDPKLIPVGSWEELLEGEDGVILAVGYPVYQALKAAEELKKEGIRLGVVNARFVKPMDEQMLLDLCSRYDLFITVEDNTVVGGFGSGVLEFLSNRGILKRVITLGIPDRFIEHGNQNLLRNLVGIDAEGIARSVRKALRRVL
>NZ_CP007028.1|WP_025305329.1|92692_93448_-|cytochrome-c-biogenesis-protein-CcsA
MLFGSLSLYFVATLLGVCALFKRPLCGLLSVLLMLPAFGLYFFSLFYSYLREKTFPLGDPYGFISFLGNLFVPTFLFLTYKYRNLLGFAHLVAFVGFLATLFALPSSPSPYKSTLYGLHLLFASLSYLFALMGGLSAFLRLILERRLKKHVFFQAYVPLDSLRRAERLSINLAFLGFTFTLIFGSLWARTQFGKHWIDDPKLITTLLLWLYYALLSHLNLLKKLKPRRFSEGVILGAIFSLINLFFVRHNF
>NZ_CP007028.1|WP_025305328.1|91472_92672_-|methionine-adenosyltransferase
MKNIVITPITFEPVYAQQVEIVERKGTGHPDTICDYLAEELSVALCKWYQENFGAIMHHNVDKALLVGGRAEPVFGGGEVIEPIEIYLVGRAILEKDGKELENVQEFVQNVVEKWISENLRNLDPKKHIKVYAKLKPGSKDLVELFERFQKKGEVPLANDTSFGVGFAPFDDLERAVYQTERFLNSSEIKEEHPEIGEDIKVMGVRFGEKIRLTVALAFVSKYIKNEDEYFAKKEEILRKTKNYIQELLGREVELFINTADTKGSVYITVTGTSAEQGDDGQVGRGNRVNGLITPYRPMSLEAAAGKNPISHIGKIYNTVAKKISERVVEEIEEVEEAYCYIVSQIGKPINEPQVLDVKIRTKKNLSAIQELARKIAEEELERMPDVWKGFLERRYSVA
>NZ_CP007028.1|WP_025305327.1|90972_91476_+|archaemetzincin-family-Zn-dependent-metalloprotease
MFIYLIAVGSVEKRLLLACAKNVKEVFGFEVRISDVPVYYKSAYNPHRGQFSASKLLERIKAVHLPNMLKVVGITDVDLYEEGLNFVFGVGELNGRCALVSIYRLKTPDERLLFERTFKELNHELGHTFGLLHCNSPRCVMNFSNSVLEVDQKGRFFCEECQKKLKL
>NZ_CP007028.1|WP_025305326.1|89641_90943_-|homoserine-dehydrogenase
MEVKVGIVGCGVVGTGTVALLLENAKVIEEKTGIKLSISKVADKDWSRPREYEVPSTLRTTDYREVIESSDIVVELVGGKDFAKRLLLEALERGKHVVTANKHLLAEDGEEIFKKAKEKGLMVGFEASVGGGIPIIKALREGLVGNRVQNIYGILNGTTNYILTQMLEQDVSFDTALKRAQELGYAEADPSLDIDGWDSAHKITLLAFVGFGKLFPFEEVYVEGIRNIDLLDVELGKDLGYTLKLLAIAKRMDSEVELRVHPTFIPSDNPLAKVSDVYNAVLVEGDFVGKTMFYGRGAGSKPTASAVVSDIVDIAKSIGSCKSQSWLWESKEGFRINKNFYSRYYLRFDVPDRPGVLAKIANVLAEYQISIASVLQKEKVCKMAGREGQPIVPLVILTHKAYEMDMQRAIREIQQLPVVEGKPVIIRVEEEAY
>NZ_CP007028.1|WP_025305325.1|88976_89645_-|ribulose-phosphate-3-epimerase
MKLLAPSILSADFYRLGEQIEAVIKGGADLLHFDVMDGHFVPNITFGPVVLESIKKHCNIPLDAHLMIENVDKYIPEFIKAGADMVSIHIENNYHIHRSIELIKSLGAKAGVVINPGTPLSLLEEVLHYVDFVLLMSVNPGFGGQKFIPRSLERLRRLKEMVNAINPKVLIEVDGGIKEENILEVARAGADILVVGSGIFAHQDVQAQTRKLKNLLISSEAL
>NZ_CP007028.1|WP_051402167.1|87001_88999_+|LPS-assembly-protein-LptD
MYNFRVLFVLFLLCFGLTFGVEVFSKYMEREPDGTLVAREEVEVYYENYYIRADEVRYNPQTKEVIAEGNVYVRSTDGKLEVKKGSYAYIDLNKKVGYFLNAEGRFQRFYFKAEKAEMEGDTYTVENGEITTCPPDRKEMVLCFSKARIDQKYVISENNSLRLFRVPFAYLPIFAYPVGERRSGLLPPTVGSNTYNTFIYQQPIYWAISKDKDATLTIDLRDKQAKGFSIEYRQAFFKEDDLQFKVSYYKEPIPPGKWWEGRDPTTFRENRYRVQLSLDLGNFKAGLDTISDPYLLEDTYLRARERTVPYLTSYVIYKKDFERFLITFEAKHFYDTTSLNNERTLQKLPEIALYWKSQQLWGPIFFSLFSSYTNFYREEGLRGQRLTLFPELSIPKNLFGRVFYSNLVFENLYYFGLNQQGYKQTVSSLYFSESVPFIFDLQAGNFKFKNFLKVGYSFREKDFNNPRFDNRDQLNRTSQIDALWTGSMGYKDKEFLNLYVSSAYNYLGKYTYGGITADRRLLPIRTIVSLKPFEGVSLTTDSLYDTEGGFPLRTSNSLNLSYKNNSLTLSYQTARNLLNQRTTDQTSLSFSTSYGTAVFGLLLTRDNRIGKDLVRQASLDYRGACWSLGLLARDNYSGTRGKHIKELYLTFNIFDLQRFTVPLKR
>NZ_CP007028.1|WP_025305323.1|84532_86833_-|ribonucleoside-diphosphate-reductase-subunit-alpha
MKVVKRAGVLEDLDIGKIRIVIDFACKGLRVDPLELEMDAQIQFRDGITTKEIQQLLIRTAAEKVSAENPDWTYVAARLLLYDLYKDVGHLRGYKVKDKINGKYKPYNPESFYELIKECTERGIYGEYLLENYTKEEIDQLAHYIKPDRDLLFTYTGIKVLYDRYLVRDEEGRVIELPQEMYMLIAMTLAIPEKKEERLMWAKTFYDLMSEHLISLATPTLMNARRPYTQLSSCFVLTVDDDLYDIFDNVKKAGMISKFAGGLGIYLGKIRATGAPIRKFKGASSGVLPVVKIINDVMVYVDQLGMRKGSASITLDIWHKDVLDFLEVKTNVGDERKKAHDIHPAISIPDLFMKRLKENGKWTLFDPYWCKNVRDGKNLEDFYGEEFEELYLKLEKELPDYAKKEISAFELWKRLLTVIFETGEPYIFFRDTANRLNPNKHCGMVYSSNLCHEIVQNQSASTHISETLSEDGTITHVKKSGDVVVCNLGSINLGKVWTKEDLERVVPILVRMLDNVIEMNFYAIKEAEYTNKRYRAIGIGVSNYHYCLVKNGIPWESEEHLRFASSLFERIAYYAIKGSMELAKERGKYPLFDSSDWSKGIFFGRTPEENQRLSQENGNNFDWIGLAEEVKRNGMRNAYLLALMPTGSTSLIVSATPSIDPIFAKFYKEENMSGILPQVPPEVDKYFWYYKSAYNIDQEWIIRAAAERQKWIDQAQSLNLFIDPERIDGPTLSKLYTLAWELGLKTVYYCRSKSMTDIEECESCAT
>NZ_CP007028.1|WP_038531922.1|83915_84554_-|HAD-IA-family-hydrolase
MRKLCNIRLLIFDLDGTLIDSAEDIALHVGRVYRELKSKDVPADEVKKNIGDGARSLLANFFQGQELEEALERFLHYYISEPVIHTKPYEGVMETLEGLKERGILLAVATNKPHAITLEVLKRLKMFHYFDEVLGADLLPEKKPSPLPLLEIAKRLEVSPELGLMVGDSENDILAGRRAGMLTAHARWGYKAPQSPPDYHLDHPKDLLHLID
>NZ_CP007028.1|WP_025305332.1|97328_98513_+|TRC40/GET3/ArsA-family-transport-energizing-ATPase
MRIILFSGKGGVGKTTVSAATGYRLSKLGYKTIVVSLDPAHSLGDSFDIPEEEKIKAKGLPIKINDNLYIQEIDVQEEIDRYWGDVYRFLELLFNTTGLSEIVSEELAILPGMEEVTSLLYVNKYYREKEFDVLILDLPPTGESLRFVSMPTVLKWYMKKIFKVERTVMKIARPVAQRLTDVPLPDDEYFKALENFYEKLKGVDEILIDPEITSVRLVANPEKMVLKESQRAMLYFNLFGVNVDAVVVNKVLPPVLSECESMSKWVITQKKYLEEMEALFYPIPIFKVPLMEDEVVGEERLSILADLIYGDRDPSTVFFKEKPYEFIEEGDGYIVKLRSPFLSKEGLSVIKSDGEIVVRWKNFKSHIMLPRKLRDYEPVGAKLEDGFLKIRLEK
>NZ_CP007028.1|WP_038531926.1|98496_99186_-|uracil-DNA-glycosylase
MSLRKLIATASALRELGFDEVYITEDTTEEKREEPIKEEKEDKAELLRKLYQQMEEERKCILYEGASGYVFGEGDPNSPVVFIGEAPGEEEDKLKRPFVGRAGQYLNSKLEQVGLKREKVYITNVVKSRPPGNRTPTREEMMTCLPYLRKEIEIIKPKLLVCLGSTAMKGILGKEYPITKYRGQVFPYPYNPSIKVFLTYHPAYVLRNPSADKEFTEDLKKVVQLISQA
>NZ_CP007028.1|WP_038531928.1|99182_99827_-|(d)CMP-kinase
MKIAIDGPSASGKSTIARLLSQRLGIPYLETGLLYRFFGYIAYKRGTIELPPDELFKEDFKVVIDVGKTEVYWKGKRLSEELRGEEVGRYASLLGEVPAFRERMIKFFRELVGSSQVVGEGRDVGTHIFPQADYKFFITASPEERARRRYLELKERGMDVSYEDILKAIQERDYRDANRPLYPFKPAEDALIIDTTNKRVEEVLEYILSIIKER
>NZ_CP007028.1|WP_025305334.1|99826_100927_-|PilT/PilU-family-type-4a-pilus-ATPase
MLALILKRAVELGASDIHLKVGSLPVLRIKKKGLVRMEDVHPIDDRMMASFVEEIIGKNVKKMAEFEELGETDTSYSLRGVSRFRVNIYKQRGSIGMAFRVIPYSVPPFESLNLPEVMRRIVLENTKGLILVTGPTGSGKSTSIASLINEINLRKEATIITIEDPIEYLFKDEKSYIVQREVGIDTSSFAKGLRAALREDPDIIFVGEIRDTETAMIALQAAETGHLVLSTLHTLDAKETINRFIGLFNLEVREQIRVQLAETLVAVFSQRLVPRADRTGVVPAVEVLINTASIKECILDPTKTDEIPMLLEKGRPVYGTQTFDQHLEELYRKGIIDFNTAIAYANKPTDMEIKLKGISAGGRGYF
>NZ_CP007028.1|WP_038531930.1|100895_101930_-|recombinase-RecA
MIEEQQKEILEKRKALESALASIERRFGKGSIMPLRSAERVKVEAIPTGSLALDIATGVGGIPKGKIIEIFGPESSGKTTLALHVIAEAQKRGGIAVFIDAEHALDPKYAQKIGVDLDNLYISQPDYGEQALEIAESLLRSGAVDVIVIDSVAALVPKDELEGEIGEAHVGKQARLMAQALRKLKSLAHNANAAVIFINQLREKIGVMFGNPETTPGGRALKFFADMRLDVRRIGDAKEGDSRIGSRVRVKVVKNKLAPPFREAEFDMIYGEGICKLCDLIDTASELGVIKKSGAWYSYGEIRLGQGRDQAKKFLQENPELAQEIEKRVREVAKIAGTDTQEGG
>NZ_CP007028.1|WP_025305336.1|101955_102240_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MLKEDVVEKVAQLARLKLTEEEKETIGKQLLSILEFVNQLNEVNTEGVDAVWYGQEGTPLREDIPKREFSQEKALANAPERENGFFVVPKILEL
>NZ_CP007028.1|WP_025305337.1|102233_102632_-|YjbQ-family-protein
MSVLKVRTTKRTSFVNITHMVKEEVKKSGVKSGLCLIYVPHTTCAVFINEGADPDVIRDISYALERLIPWSDPNYAHAEGNSAAHIRSSIIGNSRVVPIEDGELTLGTWESIFLAEFDGPRERKIIIKVIPC
>NZ_CP007028.1|WP_025305338.1|102628_103117_-|4-vinyl-reductase
MEPLGDKFRALAEAIERESVLVHRAALIDGYRDIYKFSNLGIDKLIKKATEYGGKKGAKILKERYGVITDRLDEALEILTVIAESSRLIDVFEFDIDAMEIRVEGSILVEAVGSSKKPVCEPMAGFFSGFLSELLGKKVEVKETACAAQGHEKCIFKISIKE
>NZ_CP007028.1|WP_025305339.1|103164_104151_-|UDP-glucose-4-epimerase-GalE
MKVLVTGGAGYIGSHMVKLLVEKGHEVLTFDNLSNGHEWAVINRQLVVGDLLNYKQIEEVLLDFKPDVVMHFSAKVVVPESVEKPLLYYENNFYGTLNLLQAMKRAKVKYLIFSSTAAVYGIPERVPVKETDPTNPISPYGWSKLFSEQAIKDFGRAEGIKYGILRYFNVAGADPDGKIGQVSKNPTHLILRALKTAKGELPYIEVYGTDYPTHDGTGIRDYIHVMDLCQAHLDVLDYLMNGGESDVFNVGYGRGYSVLEVIETVKKVTGVDFKVVYADRRPGDLPQVVADATKLKTLVGWTPKYDDLEFIIKTAWNWEKNYTYKACL
>NZ_CP007028.1|WP_025305340.1|104147_105113_-|GDP-mannose-4,6-dehydratase
MHILVTGCAGFIGWRVSKRLLEEGHQVVGIDNLNDYYDVRLKEYRLEDLKAHKNFTFYQGDIENLEFLEGVFKKYSFDAVINEAARAGVRASLENPFVYFTTNALGTLNLLELCKNYGVPKFVLASTSSLYAGQPMPFKEDLPVNTPISPYAASKKSAEVIAYTYHYLYGIDVSVVRYFTVYGPAGRPDMSVFRFIKCIMEEKPLEVFGDGSQSRDFTYIDDIAEGTILALKPLGYEIINLGNNQPHKLSEVIGLIEKFTGKTARVENREFHKADLKATWADITKAKELLGWQSKVSLEEGIRRTVDWFKENWHWLKDIKL

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Crispr_ID: NZ_CP007028_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007028_3

651865-652564

Orphan

Consensus_repeat	Method
CTTTCAACTCCACACGGTACATTAGGAAC	CRISPRCasFinder
CTTTCAACTCCACACGGTACATTAGGAAC	CRT
CTTTCAACTCCACACGGTACATTAGGAAC	PILER-CR

10 spacers

The CRISPR arrays of NZ_CP007028_3

>merge|NZ_CP007028|3|651865-652564|CRISPRCasFinder,CRT,PILER-CR
TTTTTAACTCCACACGGTACATTAGGAACGTAGTCCCTGAACACTTGCATACCATGATTGAGTATCTTTCAACTCCACACGGTACATTAGGAACACCATCCACCAGCCAGACCCAACTGGGGGACCGTATCTTTCAACTCCACACGGTACATTAGGAACACCATCCACCAGCCAGACCCAACTGGGGGACCATATCTTTCAACTCCACACGGTACATTAGGAACAGGAACCAGACAAAGGAGATAAGAACAACAAAGAAAAAAGCACCTTTCAACTCCACACGGTACATTAGGAACCTTCCTTCGGAGGATGAGGGCTTACCTAAAGAAGGTTAAGACTTTCAACTCCACACGGTACATTAGGAACACCGCAACACGTTTCTTTACCTACCTAAACCATTACTTTCTTTCAACTCCACACGGTACATTAGGAACCACCCACAATAACAAAAAACAAAGATAAGAACACACTTCTTTCAACTCCACACGGTACATTAGGAACATACACTTTGGTTGACCAGGAAGCATGGCGGAGTATGATCTTTCAACTCCACACGGTACATTAGGAACGCTAATATTCCTTTCCATAGCCTGCACCTCCTTAAAACTTTCAACTCCACACGGTACATTAGGAACTGTTAGAGGTGGCTAAACTTGAGATTTGGGCGGTTACTTTCAACTCCACACGGTACATTAGGAAC

>NZ_CP007028|3|3|651865-652564|CRISPRCasFinder
TTTTTAACTCCACACGGTACATTAGGAAC	GTAGTCCCTGAACACTTGCATACCATGATTGAGTAT
CTTTCAACTCCACACGGTACATTAGGAAC	ACCATCCACCAGCCAGACCCAACTGGGGGACCGTAT
CTTTCAACTCCACACGGTACATTAGGAAC	ACCATCCACCAGCCAGACCCAACTGGGGGACCATAT
CTTTCAACTCCACACGGTACATTAGGAAC	AGGAACCAGACAAAGGAGATAAGAACAACAAAGAAAAAAGCAC
CTTTCAACTCCACACGGTACATTAGGAAC	CTTCCTTCGGAGGATGAGGGCTTACCTAAAGAAGGTTAAGA
CTTTCAACTCCACACGGTACATTAGGAAC	ACCGCAACACGTTTCTTTACCTACCTAAACCATTACTTT
CTTTCAACTCCACACGGTACATTAGGAAC	CACCCACAATAACAAAAAACAAAGATAAGAACACACTT
CTTTCAACTCCACACGGTACATTAGGAAC	ATACACTTTGGTTGACCAGGAAGCATGGCGGAGTATGAT
CTTTCAACTCCACACGGTACATTAGGAAC	GCTAATATTCCTTTCCATAGCCTGCACCTCCTTAAAA
CTTTCAACTCCACACGGTACATTAGGAAC	TGTTAGAGGTGGCTAAACTTGAGATTTGGGCGGTTA
CTTTCAACTCCACACGGTACATTAGGAAC

>NZ_CP007028|3|2|651865-652564|CRT
TTTTTAACTCCACACGGTACATTAGGAAC	GTAGTCCCTGAACACTTGCATACCATGATTGAGTAT
CTTTCAACTCCACACGGTACATTAGGAAC	ACCATCCACCAGCCAGACCCAACTGGGGGACCGTAT
CTTTCAACTCCACACGGTACATTAGGAAC	ACCATCCACCAGCCAGACCCAACTGGGGGACCATAT
CTTTCAACTCCACACGGTACATTAGGAAC	AGGAACCAGACAAAGGAGATAAGAACAACAAAGAAAAAAGCAC
CTTTCAACTCCACACGGTACATTAGGAAC	CTTCCTTCGGAGGATGAGGGCTTACCTAAAGAAGGTTAAGA
CTTTCAACTCCACACGGTACATTAGGAAC	ACCGCAACACGTTTCTTTACCTACCTAAACCATTACTTT
CTTTCAACTCCACACGGTACATTAGGAAC	CACCCACAATAACAAAAAACAAAGATAAGAACACACTT
CTTTCAACTCCACACGGTACATTAGGAAC	ATACACTTTGGTTGACCAGGAAGCATGGCGGAGTATGAT
CTTTCAACTCCACACGGTACATTAGGAAC	GCTAATATTCCTTTCCATAGCCTGCACCTCCTTAAAA
CTTTCAACTCCACACGGTACATTAGGAAC	TGTTAGAGGTGGCTAAACTTGAGATTTGGGCGGTTA
CTTTCAACTCCACACGGTACATTAGGAAC

>NZ_CP007028|3|3|651866-652564|PILER-CR
TTTTAACTCCACACGGTACATTAGGAACG	TAGTCCCTGAACACTTGCATACCATGATTGAGTATC
TTTCAACTCCACACGGTACATTAGGAACA	CCATCCACCAGCCAGACCCAACTGGGGGACCGTATC
TTTCAACTCCACACGGTACATTAGGAACA	CCATCCACCAGCCAGACCCAACTGGGGGACCATATC
TTTCAACTCCACACGGTACATTAGGAACA	GGAACCAGACAAAGGAGATAAGAACAACAAAGAAAAAAGCACC
TTTCAACTCCACACGGTACATTAGGAACC	TTCCTTCGGAGGATGAGGGCTTACCTAAAGAAGGTTAAGAC
TTTCAACTCCACACGGTACATTAGGAACA	CCGCAACACGTTTCTTTACCTACCTAAACCATTACTTTC
TTTCAACTCCACACGGTACATTAGGAACC	ACCCACAATAACAAAAAACAAAGATAAGAACACACTTC
TTTCAACTCCACACGGTACATTAGGAACA	TACACTTTGGTTGACCAGGAAGCATGGCGGAGTATGATC
TTTCAACTCCACACGGTACATTAGGAACG	CTAATATTCCTTTCCATAGCCTGCACCTCCTTAAAAC
TTTCAACTCCACACGGTACATTAGGAACT	GTTAGAGGTGGCTAAACTTGAGATTTGGGCGGTTAC
TTTCAACTCCACACGGTACATTAGGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007028.1\|WP_025305909.1\|658438_659059_+\|7-cyano-7-deazaguanine-synthase	unknown	unknown	gnl\|CDD\|223676
NZ_CP007028.1\|WP_038532079.1\|659979_660831_-\|YicC-family-protein	unknown	unknown	gnl\|CDD\|236993
NZ_CP007028.1\|WP_025305905.1\|653996_655364_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_CP007028.1\|WP_025305901.1\|650988_651483_+\|metal-binding-protein	unknown	unknown	gnl\|CDD\|370771
NZ_CP007028.1\|WP_025305904.1\|653125_653995_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|184514
NZ_CP007028.1\|WP_038532394.1\|647731_649156_-\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|236447
NZ_CP007028.1\|WP_025305903.1\|652797_652989_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025305912.1\|660832_661141_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025305894.1\|644536_646984_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223690
NZ_CP007028.1\|WP_038532073.1\|651485_651821_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025305897.1\|649185_649530_+\|PIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|350250
NZ_CP007028.1\|WP_025305895.1\|646970_647735_-\|ribonuclease-PH	unknown	unknown	gnl\|CDD\|178914
NZ_CP007028.1\|WP_038532070.1\|649513_650140_+\|phosphoribosylanthranilate-isomerase	unknown	unknown	gnl\|CDD\|238237
NZ_CP007028.1\|WP_051402151.1\|657795_658035_+\|DUF454-family-protein	unknown	unknown	gnl\|CDD\|377291
NZ_CP007028.1\|WP_156916185.1\|644246_644513_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025305900.1\|650547_650985_+\|copper-chaperone-PCu(A)C	unknown	unknown	gnl\|CDD\|377298
NZ_CP007028.1\|WP_169727086.1\|658001_658442_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025305899.1\|650111_650501_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|224961
NZ_CP007028.1\|WP_025305910.1\|659033_659786_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP007028.1\|WP_038532076.1\|655360_657739_+\|endopeptidase-La	unknown	unknown	gnl\|CDD\|223542

Protein	Function_ID	Function_description	E-value
NZ_CP007028.1\|WP_025305909.1\|658438_659059_+\|7-cyano-7-deazaguanine-synthase	gnl\|CDD\|223676	COG0603, COG0603, Predicted PP-loop superfamily ATPase [General function prediction only].	1.17048e-25
NZ_CP007028.1\|WP_038532079.1\|659979_660831_-\|YicC-family-protein	gnl\|CDD\|236993	PRK11820, PRK11820, YicC family protein.	4.27124e-71
NZ_CP007028.1\|WP_051402151.1\|657795_658035_+\|DUF454-family-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	8.17015e-13
NZ_CP007028.1\|WP_025305901.1\|650988_651483_+\|metal-binding-protein	gnl\|CDD\|370771	pfam09988, DUF2227, Uncharacterized metal-binding protein (DUF2227). Members of this family of hypothetical bacterial proteins possess metal binding properties; however, their exact function has not, as yet, been determined.	1.73057e-35
NZ_CP007028.1\|WP_025305904.1\|653125_653995_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|184514	PRK14110, PRK14110, F0F1 ATP synthase subunit gamma; Provisional.	6.6373e-169
NZ_CP007028.1\|WP_038532394.1\|647731_649156_-\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0
NZ_CP007028.1\|WP_025305895.1\|646970_647735_-\|ribonuclease-PH	gnl\|CDD\|178914	PRK00173, rph, ribonuclease PH; Reviewed.	3.2586e-164
NZ_CP007028.1\|WP_025305894.1\|644536_646984_+\|CBS-domain-containing-protein	gnl\|CDD\|223690	COG0617, PcnB, tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis].	2.53542e-62
NZ_CP007028.1\|WP_025305897.1\|649185_649530_+\|PIN-domain-containing-protein	gnl\|CDD\|350250	cd18683, PIN_VapC-like, Uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	3.75298e-13
NZ_CP007028.1\|WP_025305905.1\|653996_655364_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	1.12615e-161
NZ_CP007028.1\|WP_038532070.1\|649513_650140_+\|phosphoribosylanthranilate-isomerase	gnl\|CDD\|238237	cd00405, PRAI, Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are monomeric, monofunctional and thermolabile, but in some thermophile organisms PRAI is dimeric for reasons of stability and in others it is fused to other components of the tryptophan biosynthesis pathway to form multifunctional enzymes.	4.04921e-80
NZ_CP007028.1\|WP_025305900.1\|650547_650985_+\|copper-chaperone-PCu(A)C	gnl\|CDD\|377298	pfam04314, PCuAC, Copper chaperone PCu(A)C. PCu(A)C is a periplasmic copper chaperone. Its role may be to capture and transfer copper to two other copper chaperones, PrrC and Cox11, which in turn deliver Cu(I) to cytochrome c oxidase.	3.61236e-47
NZ_CP007028.1\|WP_025305899.1\|650111_650501_+\|PaaI-family-thioesterase	gnl\|CDD\|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	1.97593e-19
NZ_CP007028.1\|WP_025305910.1\|659033_659786_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	2.10692e-22
NZ_CP007028.1\|WP_038532076.1\|655360_657739_+\|endopeptidase-La	gnl\|CDD\|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0

>NZ_CP007028.1|WP_038532073.1|651485_651821_-|hypothetical-protein
MKFLVFFRPVSIRLFEPYCPDRLELQYDRKFMPILKKALRRALERRHELRPIRPMDFYRLERGKSKDFRLVVSFYLAKQIENIPPELKRHFWFILHEELSNTIKEEFAMMS
>NZ_CP007028.1|WP_025305901.1|650988_651483_+|metal-binding-protein
MALGRTHELINLLALPGFLYFLPKEFYLPFSVGYVLGTFFLSPDLDLKHSKPSKRWKALKILWHPYQKKSKHRGISHIPILGTFTRLLYIFLIITALYYLLYFFLSYYWQEGTQKISQLHPLILVEELAYKEWTFYALLGLIASELTHISLDLLWSFWKRIKPF
>NZ_CP007028.1|WP_025305900.1|650547_650985_+|copper-chaperone-PCu(A)C
MVRAVLFGLSAVALALAQPKIEVKDPWVRLVPPNAKATAAYMKIENKGTEADRLVDASSNVSKITELHETVEGKMRRVKAIEVPAGKTVELKPGGLHVMLIELKEPLKEGQTVEITLKFEKSGEIKVQAPIKKGMGGMHHHHHGH
>NZ_CP007028.1|WP_025305899.1|650111_650501_+|PaaI-family-thioesterase
MQLRTHVKIDQELSGTPIEVGEGYAVVELKTKENMRADEKNLVHGGFIFSLADYCAMLTVNEPTVVLASAKVDFKKPVVVGDTLRAEGRLLRAEGKKRWVEVKVYRNQDLVFLGEFLCVVPDKHVLDVE
>NZ_CP007028.1|WP_038532070.1|649513_650140_+|phosphoribosylanthranilate-isomerase
MERSVKVKFCGIKREEDIKKALELKVDYVGFILYPKSPRFVGWERLVGLLELAQGVKRVGVFVNPTFEEIEKAFELGIDLVQLHGEEDFEFAKRVGLERVIKAFRVKDQIHVEEAWKQAYAILLDTYSDKAYGGTGKSFDWSIAQALVEEGFKVFLSGGLNPKNVSLAVQQVKPYAVDVSSGIEKEPGVKDHKKMEEFIHAVENPCKD
>NZ_CP007028.1|WP_025305897.1|649185_649530_+|PIN-domain-containing-protein
MKAIEVSSILKLLEGKEEGHKIEQELRKIEKRKEKVYVSNYTLLELAYLLEFVYGLSRERVAKVLKTLLEDPLFKVEEEEVWKEALKLYLEGAELLSALREVQYRRADVDGTVG
>NZ_CP007028.1|WP_038532394.1|647731_649156_-|F0F1-ATP-synthase-subunit-beta
MMKGRIVQVIGAVVDVEFPDKNLPPVRHGLKTIRRFIDDRGNWTQEELYFEVAQHIGENRVRTIAMGPTDGLVRGQEVEYLGGPIKVPVGRATLGRIFNVVGQPIDEAGPVNAEEYWPMFREPPPLEEQSTKVEILETGIKVIDLLEPYVKGGKVGLFGGAGVGKTVLMQELIHNIAKFHKGFSVVIGVGERTREGNDLWHEMKESGVLPYTVMVYGQMNEPPGVRFRVAQTGITMAEYFRDVEGQDVLVFIDNIFRFVQAGSEVSTLLGRLPSAVGYQPTLNTDVGEVQERITSTKKGSLTSIQAVYVPADDITDPAPYSVFAHLDATTVLARRLAELGIYPAVDPLESTSKYLAPEFVGTEHYETAMEVKRILQRYKELQEIIAILGMEELSEEDKAIVNRARRIQRFLAQPFHVAEQFTGMPGKYVRLVDNIRSFKEILTGKYDHLPEQAFYMVGTIEEVIEKAKAMGAKV
>NZ_CP007028.1|WP_025305895.1|646970_647735_-|ribonuclease-PH
MRKDGRKPNELRPIKIERDYLKYAEGSVLVEFGNTKVICAVSVQDGVPPFLKGKGQGWITAEYSMLPRAGQTRNIRESVAGRIGGRTHEIQRMIGRAMRTALDLTKVGERTFWVDCDVLQADGGTRTASITGAFVALADAVIKLYNEGILNSTPIKDFVAAVSVGIVGDEVLLDLNFEEDSSAKVDMNVVATGQGMISEIQAMGEENTFTKEQFDKMFALAMGGIKQLVELQRSFFEIKGGIWFRKDIKQARLE
>NZ_CP007028.1|WP_025305894.1|644536_646984_+|CBS-domain-containing-protein
MKVIILEEGADLDALSCAYGVLLLYQDAYLLKPSLLSRRASEVFKRFKERFRILEELPQEFDLVLVDAHHVEEYKLPGVKEIYIFDHHPKAPKGFKGKVDEVGSATTLVVEELQRLNVDISPEDATLLALGIYEDTGSLTYEGTTERDALALAWLLKKGANLRTIREFLRESLSKEEIDFLSKSLVALEKLFIDGSKVVVFVLRSEEYNPDFLQVAYRLEDVKDADAFFVIVSVGSKTYLFGRGLKGRFDTSKILEAFGGGGHSFASAVKLENVSAERLKTLLVQLLKGENPAIRVRDVMNYPPFALREDMTVEEALISLAERNFAGAPVLDQEGRLVGVVYKKVLLKVAKLFPSKQVKDFMQTQFHTLSPEDFVWDAEAILSTYGEKLIPVVEDQKLVGVITRLDLMQTLIKQTEPLKPSHRKVQLPKEVEELARVVGKICQELGFKGYLVGGVVRDILMGRRIWDLDFVVEGDGIKVAERFAQHYRVNVHPFPEFGTAHLKVGDFKIEFATTRRETYPHPGAYPVVEPASLKEDLFRRDFTINAMAISVMEEDFGTLIDYFGGLRDLKDKLIRILHPLSFVEDPVRILRALRFAGRFDFKLSKSTEKAMLNALSMHLLKQASRGRLLKELTLAFREEKLLDILKLYRQYKVLEELIDGFQWSQDLELKLEKLKEVVSWHKIEFPDKKLEYGWLYLVILLEKVKGEEFLRDMSAPAWVRELYRTYKEQAKEVIRKLHQAKKPSEVYLTLKGFSEPFYLLLAIEESLRPKIVLYMEKLSKLKVDVSRFSGLKGKELGKAIENEKLRLMDETFTLT
>NZ_CP007028.1|WP_156916185.1|644246_644513_-|hypothetical-protein
MRKLATLLLSFLLVFVDFKTAEHHHEDHQFHQDCELCIIQHQPQHKEDVKLQPRLENPVLFVEKEKTQETAPKLEIPYNHPIRAPPVG
>NZ_CP007028.1|WP_025305903.1|652797_652989_+|hypothetical-protein
MGCKKKKVVKTTILLPSDVHQALRIEAITKKMSMGELIVQKLRELEEYKQKYGGVVKAEDYLT
>NZ_CP007028.1|WP_025305904.1|653125_653995_+|F0F1-ATP-synthase-subunit-gamma
MPKLSPRDIRRKIQGIKNTRRITNAMKVVSAAKLRKAQEAIYASRPYSERLYEVLAHLSAHVDMSAHPLLEVREERKVDIILITADKGLAGAFNSNAIKKAEELIAEKNQNGIKVSLILIGRKGAQYFQKRSWKVLKAYEEVFRKEINFEVVKEVGELVRQRYQNKETDGVYLINNEMITRASYKPVVRRFLPFERIEQKEQDYSSYEFEVDAETFINKLIDLYLNYQLYRAMLESNAAEHFARMVAMDNATRNADELIRTWTLIFNKVRQESITYELIDIVNAVEAMK
>NZ_CP007028.1|WP_025305905.1|653996_655364_+|signal-recognition-particle-docking-protein-FtsY
MFGFFKKSEEEKLAEKGDKSAILKLIEKGKKDKAIEILERFKEDPELRPILFKLYMEEGKYYYAYQLVEYYDKNLATAKERALLYEKVGEIQKAVEEYSKVGDYESLYRAGMLLKEAQPKESLEFFERAFKLANEIQKKELEEHILEIKKKLGLVEVKKEGFLERLRKGLRKTRELLEFGVIFAGRKVDEELLEELEERLIRADIGVKTAEQLVEELRKEAIRKNIKTWEELLPVLREKLLSYIGNCKGELKEGKVYLFLGVNGSGKTTTIGKLAYRFKSQGKRVLLCAGDTFRSAAIEQLQVWAQRSGADIVYKEEGADPASVVYQALEKAQKENYDVVLIDTAGRLHTKEPLIRELRKIKQVIQKFYPEELTETLLVLDATIGQNSLSQAKVFKEAVDVSGIVLTKLDGSAKGGAVVPICSELKIPIKLLGVGEGLEDLQEFDPKTFVEELTS
>NZ_CP007028.1|WP_038532076.1|655360_657739_+|endopeptidase-La
MMMEDFFKLPEVPSEEFELPAMPLRDLVVFPAMVVPLFVGRDFSVRAIESALKRDRLILLVLQKEKSVEEPDKEGIYSMGVIAHIIRATPLEEGKLKILVQGIKRAHIKDYYKKEDHYWALVKAIDEKEINPEELSREDRAYISAVKELLDRAVALGKQVIPDLLMVIRELEDPGKLADLVASISDIKSHEAQKVLESLDPIERLKLVHQYLSNEVGMLEVQSRIRNTARERIEKEQREYFLRQQLKAIQEELGELDEKKEEIENYRKKLAQLKLSKEVREEIEKQIKRLERMHPESAEAGVIRTWLDWVLELPWNKKTKDRYNLERVQQILDRDHYNLEKVKERIIEYLAVKKLTKGKSTAVQILCFVGPPGVGKTSLGKSIAEALGKKFVRISLGGIRDEAEIRGHRRTYVGALPGRIIQAIKQAGTKNPLIVLDEVDKISISFQGDPAAALLEVLDPEQNKTFTDLYIGLPFDLSEVFFICTANRVDTIPRPLLDRMEVIYLSGYSEEEKVFIAKNHLLPKLLPLHGFKEGEVIFQEEALLEVIRGYTRESGVRNLQRQLGTILRKLALRKLRGEKPPFEVKAQDVKGFLGVPKRFTDKEDTPMVGLAIGLAWTEVGGEIMLIEATRFKGKGNLILTGSLGDVMKESAQAAMSYIKSKAEDYGINPEEFSNWDVHIHVPEGAVPKDGPSAGITIATALLSLFTDIPVRSDIAMTGEVTLRGRVLPVGGLKEKILAAKRAGIYEVILPEKNKDEVLEDLPAYVRDKMTFHFVKDLDQVFEKALVSNPRKT
>NZ_CP007028.1|WP_051402151.1|657795_658035_+|DUF454-family-protein
MRKLLYRTIAGILLLLAVLGVFLPLLPTVPFVLLAVFFLVRSSKRDLVRIKRVPYIGKILYPYIKRVAKWNTQQPSSST
>NZ_CP007028.1|WP_169727086.1|658001_658442_+|hypothetical-protein
MEYTTAKFFHLIGVFLWVASSSSLGLFMIYGNFKDTKCDKHILRNFYRWMTNLEIAGFVLALAMGFYMLHLLKYRFDINWLNYKLPIVLLLFLPLEVLNFWFVNVYIPKSQDKEKAYKRYDLFNYIVALPLLVGGLVVVYLAVVKP
>NZ_CP007028.1|WP_025305909.1|658438_659059_+|7-cyano-7-deazaguanine-synthase
MKKSVVLFSGGVESTCVLYLKLLEGQVVYPVYVKCGMPWERLEYVKATELWQETKRKFSKLMPIKVLPLKTYHKKYKAIETEEELFIPLRNLTLLTAVAGYALSKRAESVSIGSLGLYPFPDNNLAYLKEVERLITEGSKQRLKVEVPLFGMEKGEVVKRFSKWVPLHRTFSCVNPVLRNGKILHCGICIKCKEREEAFKEAQIPL
>NZ_CP007028.1|WP_025305910.1|659033_659786_-|sulfite-exporter-TauE/SafE-family-protein
METYLIPILASIVAGFINAIAGGGTLITFPALVFAGLDPLSANITNTVALWLGPFTSALSYRKTLRENFSTLKTFLPPSLLGALLGAFLLIHTPSETFKKAVPFLIGFATLLLAFSEFILKFITRLGNSSKFLPILLQFLTAIYGSYFGAGIGIMMASSIVLSGVSNMQLTIALKNFLGFVINLLGALIFLFSGKVAFNFVLVMMPAFMLGGYLGAVVAKRLNQRTAKAVIVAWGFLLSFVFFIKEFGLL
>NZ_CP007028.1|WP_038532079.1|659979_660831_-|YicC-family-protein
MRSMTGLGRATAEDEERKVTVFIKTLNGKGLDVSIRSNINLYEFEFEVRNKIREYLQRGTVSVLVQVEAKKPKGNVVNPDALVSTFQFFKDLAQRSGFNLSDDMAFYASLRYVEIAEEELEEETKALIIQALTDALKEVVKSREEEGAKLKEDLLSRLRIIREHLRNILENKDSILERTKKRVLEKAKELNLPEGNPTVLNEISLILSKMDIEEEVTRFKVHLERFEGLLDAQGEVGRKLEFLLQEMHREINTLGNKMPELSQWVVEIKTEVDRLKQQVANIE
>NZ_CP007028.1|WP_025305912.1|660832_661141_-|hypothetical-protein
MYDWKKYKEKLLALRELIERERPFGADVDVELVLPEDPQFKLHKEIPYLLVRFEVSENITKERKIELFDYYLEKDTNELIKLITDMIEEFVAESESSEYGGG

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Crispr_ID: NZ_CP007028_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007028_4

805983-807143

TypeIII

Consensus_repeat	Method
CTTTCAACTCCACACAGTACATTAGGAAC	PILER-CR
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CRISPRCasFinder
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CRT

17 spacers

cas6,cas2,cas1,cas4,cas3,cas8b2,cas7

The CRISPR arrays of NZ_CP007028_4

>merge|NZ_CP007028|4|805983-807143|PILER-CR,CRISPRCasFinder,CRT
GTTCCTAATGTACTGTGTGGAGTTGAAAGTAGAGGGGAACACTTACCCCCTCGGCGGGCATATCCAGTTCCTAATGTACTGTGTGGAGTTGAAAGCGGTTTCTCCAGCCACGCCGAATTGCTTTAGGGTTCGTTCCTAATGTACTGTGTGGAGTTGAAAGCCACTTCAACCCTCTGCAGATCTGCGGATCGTAGGTGGTTCCTAATGTACTGTGTGGAGTTGAAAGAGCTTATAGCTTTGGTTTTCAGTAGTATAGCTAAAGGTTCCTAATGTACTGTGTGGAGTTGAAAGCAATTTTTTCAATTTTCAAGCGTAGGTCAAAAAGAAAGTTCCTAATGTACTGTGTGGAGTTGAAAGCCTCTTCAGTGAGGAAAGCAAGGTATTCCTTAAAGGGGTTCCTAATGTACTGTGTGGAGTTGAAAGAAGCACGAGTAAAATCAAAGCGACCTCCATAGCGGTCAAGGTCAATTAAAAGGTTCCTAATGTACTGTGTGGAGTTGAAAGAAGTCTTAACTATGTAGTCCCTCATAACCTCATCCTCCAGTTCCTAATGTACTGTGTGGAGTTGAAAGCTCTATCTCTCGTGCGTAGCCTTCCCAGACCTGAAGGTTCCTAATGTACTGTGTGGAGTTGAAAGAAATACCCACAAAAACGCCAAACTCTGAACCCTGAGGTTCCTAATGTACTGTGTGGAGTTGAAAGCAAAATAATATGGAGGTAAGGTTGTCCCTAAAGTCGTTCCTAATGTACTGTGTGGAGTTGAAAGCAAAATAATATGGAGGTAAGGTTGTCCCTAAAGTCGTTCCTAATGTACTGTGTGGAGTTGAAAGTAGCTTGCTGTGAAAAGTCCCAAAAGCGTTCCGACAGTTCCTAATGTACTGTGTGGAGTTGAAAGTGAAACGCCGACAGCTGGACACCATCAGAACGCCACCGTTCCTAATGTACTGTGTGGAGTTGAAAGCTCTGACTCGTTGGAAATTCTGGAAAGGATGTGGGCTAATGTTCCTAATGTACTGTGTGGAGTTGAAAGTTCTCCAGTTCGTTTTGGCATTTTGCAAGGAAAGAGGGTTCCTAATGTACTGTGTGGAGTTGAAAGCAGCTTATCCCTAAAAGCATAAGCAGGATACCAAGTGTTCCTAATGTACCGTGTGGAGTTGAAAG

>NZ_CP007028|4|4|805983-807143|PILER-CR
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TAGAGGGGAACACTTACCCCCTCGGCGGGCATATCCA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CGGTTTCTCCAGCCACGCCGAATTGCTTTAGGGTTC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CCACTTCAACCCTCTGCAGATCTGCGGATCGTAGGTG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AGCTTATAGCTTTGGTTTTCAGTAGTATAGCTAAAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAATTTTTTCAATTTTCAAGCGTAGGTCAAAAAGAAA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CCTCTTCAGTGAGGAAAGCAAGGTATTCCTTAAAGGG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AAGCACGAGTAAAATCAAAGCGACCTCCATAGCGGTCAAGGTCAATTAAAAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AAGTCTTAACTATGTAGTCCCTCATAACCTCATCCTCCA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CTCTATCTCTCGTGCGTAGCCTTCCCAGACCTGAAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AAATACCCACAAAAACGCCAAACTCTGAACCCTGAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAAAATAATATGGAGGTAAGGTTGTCCCTAAAGTC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAAAATAATATGGAGGTAAGGTTGTCCCTAAAGTC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TAGCTTGCTGTGAAAAGTCCCAAAAGCGTTCCGACA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TGAAACGCCGACAGCTGGACACCATCAGAACGCCACC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CTCTGACTCGTTGGAAATTCTGGAAAGGATGTGGGCTAAT
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TTCTCCAGTTCGTTTTGGCATTTTGCAAGGAAAGAGG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAGCTTATCCCTAAAAGCATAAGCAGGATACCAAGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG

>NZ_CP007028|4|4|805983-807143|CRISPRCasFinder
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TAGAGGGGAACACTTACCCCCTCGGCGGGCATATCCA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CGGTTTCTCCAGCCACGCCGAATTGCTTTAGGGTTC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CCACTTCAACCCTCTGCAGATCTGCGGATCGTAGGTG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AGCTTATAGCTTTGGTTTTCAGTAGTATAGCTAAAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAATTTTTTCAATTTTCAAGCGTAGGTCAAAAAGAAA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CCTCTTCAGTGAGGAAAGCAAGGTATTCCTTAAAGGG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AAGCACGAGTAAAATCAAAGCGACCTCCATAGCGGTCAAGGTCAATTAAAAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AAGTCTTAACTATGTAGTCCCTCATAACCTCATCCTCCA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CTCTATCTCTCGTGCGTAGCCTTCCCAGACCTGAAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AAATACCCACAAAAACGCCAAACTCTGAACCCTGAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAAAATAATATGGAGGTAAGGTTGTCCCTAAAGTC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAAAATAATATGGAGGTAAGGTTGTCCCTAAAGTC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TAGCTTGCTGTGAAAAGTCCCAAAAGCGTTCCGACA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TGAAACGCCGACAGCTGGACACCATCAGAACGCCACC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CTCTGACTCGTTGGAAATTCTGGAAAGGATGTGGGCTAAT
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TTCTCCAGTTCGTTTTGGCATTTTGCAAGGAAAGAGG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAGCTTATCCCTAAAAGCATAAGCAGGATACCAAGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG

>NZ_CP007028|4|3|805983-807143|CRT
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TAGAGGGGAACACTTACCCCCTCGGCGGGCATATCCA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CGGTTTCTCCAGCCACGCCGAATTGCTTTAGGGTTC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CCACTTCAACCCTCTGCAGATCTGCGGATCGTAGGTG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AGCTTATAGCTTTGGTTTTCAGTAGTATAGCTAAAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAATTTTTTCAATTTTCAAGCGTAGGTCAAAAAGAAA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CCTCTTCAGTGAGGAAAGCAAGGTATTCCTTAAAGGG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AAGCACGAGTAAAATCAAAGCGACCTCCATAGCGGTCAAGGTCAATTAAAAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AAGTCTTAACTATGTAGTCCCTCATAACCTCATCCTCCA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CTCTATCTCTCGTGCGTAGCCTTCCCAGACCTGAAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	AAATACCCACAAAAACGCCAAACTCTGAACCCTGAG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAAAATAATATGGAGGTAAGGTTGTCCCTAAAGTC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAAAATAATATGGAGGTAAGGTTGTCCCTAAAGTC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TAGCTTGCTGTGAAAAGTCCCAAAAGCGTTCCGACA
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TGAAACGCCGACAGCTGGACACCATCAGAACGCCACC
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CTCTGACTCGTTGGAAATTCTGGAAAGGATGTGGGCTAAT
GTTCCTAATGTACTGTGTGGAGTTGAAAG	TTCTCCAGTTCGTTTTGGCATTTTGCAAGGAAAGAGG
GTTCCTAATGTACTGTGTGGAGTTGAAAG	CAGCTTATCCCTAAAAGCATAAGCAGGATACCAAGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007028.1\|WP_025306064.1\|803507_804461_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NZ_CP007028.1\|WP_025306077.1\|814157_814736_+\|transposase	unknown	unknown	gnl\|CDD\|376564
NZ_CP007028.1\|WP_038532116.1\|804746_805463_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|224499
NZ_CP007028.1\|WP_025306072.1\|810768_811188_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306075.1\|812513_813677_-\|chorismate-synthase	unknown	unknown	gnl\|CDD\|235438
NZ_CP007028.1\|WP_025306058.1\|796735_797377_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306059.1\|797380_797572_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306076.1\|813681_813882_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NZ_CP007028.1\|WP_025306066.1\|805557_805749_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306062.1\|800796_803004_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|273707
NZ_CP007028.1\|WP_025306061.1\|798668_800822_+\|type-I-B-CRISPR-associated-protein-Cas5	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|273860
NZ_CP007028.1\|WP_025306070.1\|808698_810399_+\|type-II/IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|225363
NZ_CP007028.1\|WP_025306074.1\|811792_812530_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|129166
NZ_CP007028.1\|WP_025306068.1\|807594_807912_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306069.1\|807911_808706_+\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234723
NZ_CP007028.1\|WP_038532119.1\|811177_811690_+\|translation-initiation-factor-IF-3	unknown	unknown	gnl\|CDD\|234582
NZ_CP007028.1\|WP_025306063.1\|803005_803515_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP007028.1\|WP_025306065.1\|804457_804739_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP007028.1\|WP_025306060.1\|797632_798688_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09650_cas7_CAS-I	gnl\|CDD\|273846
NZ_CP007028.1\|WP_025306071.1\|810395_810776_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894

Protein	Function_ID	Function_description	E-value
NZ_CP007028.1\|WP_025306064.1\|803507_804461_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	1.95324e-148
NZ_CP007028.1\|WP_025306077.1\|814157_814736_+\|transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	2.43367e-09
NZ_CP007028.1\|WP_025306075.1\|812513_813677_-\|chorismate-synthase	gnl\|CDD\|235438	PRK05382, PRK05382, chorismate synthase; Validated.	0
NZ_CP007028.1\|WP_025306074.1\|811792_812530_-\|ABC-transporter-permease	gnl\|CDD\|129166	TIGR00056, Probable_ABC_transporter_permease_protein_HI_1086, ABC transport permease subunit. This model describes a subfamily of ABC transporter permease subunits. One member of this family has been associated with the toluene tolerance phenotype of Pseudomonas putida, another with L-glutamate transport, another with maintenance of lipid asymmetry. Many bacterial species have one or two members. The Mycobacteria have large paralogous families included in the DUF140 family but excluded from this subfamily on based on extreme divergence at the amino end and on phylogenetic and UPGMA trees on the more conserved regions. [Hypothetical proteins, Conserved].	2.48437e-102
NZ_CP007028.1\|WP_025306076.1\|813681_813882_-\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	9.7959e-14
NZ_CP007028.1\|WP_025306062.1\|800796_803004_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	2.55373e-84
NZ_CP007028.1\|WP_025306061.1\|798668_800822_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	4.91872e-43
NZ_CP007028.1\|WP_025306070.1\|808698_810399_+\|type-II/IV-secretion-system-protein	gnl\|CDD\|225363	COG2804, PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP007028.1\|WP_038532116.1\|804746_805463_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	4.25678e-33
NZ_CP007028.1\|WP_025306069.1\|807911_808706_+\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	gnl\|CDD\|234723	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed.	1.47974e-161
NZ_CP007028.1\|WP_038532119.1\|811177_811690_+\|translation-initiation-factor-IF-3	gnl\|CDD\|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	7.73981e-89
NZ_CP007028.1\|WP_025306063.1\|803005_803515_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	6.49106e-57
NZ_CP007028.1\|WP_025306065.1\|804457_804739_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.74689e-24
NZ_CP007028.1\|WP_025306060.1\|797632_798688_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|273846	TIGR01875, CRISPR-associated_protein_Cas7/Cst2/DevR, CRISPR-associated autoregulator DevR family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This model represents one such family, represented by MJ0381 of Methanococcus jannaschii. This family includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development. [Regulatory functions, DNA interactions, , ].	1.83371e-53
NZ_CP007028.1\|WP_025306071.1\|810395_810776_+\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	1.12442e-34

>NZ_CP007028.1|WP_025306066.1|805557_805749_-|hypothetical-protein
MGRKKKKVVKTTILLPSDVHQALRIEAITKKMSMGELIVQKLKELEEYKQKYGGVVNAEDYLI
>NZ_CP007028.1|WP_038532116.1|804746_805463_+|CRISPR-associated-endoribonuclease-Cas6
MRFKVKLVRAVEDNSPISIDYRRRFISLLKKIFEKEFDEESPKPYTFAVYLGKNAKIQGEYILGVESINFRFSTGDPQTAISFYNGVLKLIKENHLHNMNPKLENVYFRIVSVNIEKENEPTGFFKTLSPVVVERSTNSKNPEEKYATPRDKDFKWWLLENTQKRYRALVGEDLNVKILEIEPISVKEEFIKHYGGYVRSFLGRFRLHTESKELLRFVYQYGLGVRTGQGFGYLETLD
>NZ_CP007028.1|WP_025306065.1|804457_804739_+|CRISPR-associated-endonuclease-Cas2
MRVILFYDIDTTEKEGQRRLQRVLKTARKYLNHVQKSVFEGNLNISSIERLKHEMLRVVDKEKDSLIIYILDDNANYKREILTNVKDPTDNLL
>NZ_CP007028.1|WP_025306064.1|803507_804461_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MAEIYYITTNGTLRRDENTIMFESGEIKKKIPIENTSELFIVAEVSTNTKFLSLLSQNGIIAHFFNYYGYYIGSFYPREGNPSGHVLIKQVEHYLDKEKRLYLAKTFVLGSIINSEKLYQIDASEHLEKLKQASNVQEVMQVEGSFRKLCYKALEELTGWEFETRTKRPPQNPLNALISFGNSLVYAKVLGEIYHTPLNSTVSYLHEPSEKRHSLCLDVAEVFKPILTEGLILELIRSGTITENDFLEETEYCYLNLDGRRKFLRAFDNLLKSTVYYPKLKRKVSIRTLIRLELYKLVKHLTENEPYIPLNYHSLKK
>NZ_CP007028.1|WP_025306063.1|803005_803515_+|CRISPR-associated-protein-Cas4
MDLRELKFRGTQVAYYVVCQRKLWLFTKGISFEKESEYVQLGKLLDEISFSREKGEEFAYEPVSIDFFSTGEGLVVHEIKHSSALEQAHILQVKYYIYYLKTKGIKVSHGIIHYPKQKKLLKVEFDEKDEELINEVVRKMDEVVRKEIPPKVINKPYCKKCAYWEYCYG
>NZ_CP007028.1|WP_025306062.1|800796_803004_+|CRISPR-associated-helicase/endonuclease-Cas3
MEKIQNLLKELWAKDDGTNIREHTDKLLENLQKLRDHYRKEIEELIPKCLPAKLKEKFWEILELACEYHDYGKIHCKFQEKLGNKSVKPIKGLPEVRHNLLSPVFVNVEDELIRKIVRLLVLHHHPVEVEEVSIESVERVLKEEFKFENNPIRFMLRKKEEDYLRDNVAKMFKIPVDGLIPYYRLLKGLLLRIDHSSSSKHAQDVEDIPPDDTLSFVDEFFRQKGSSPNQMQTFVRENRDKNLVIIAPTGAGKTEAGFIYIQKKGFFMLPYRVSANGIYMRAEGMFRNYAGLLHSSALSYVFEREEDREDIQNNQEGVAFLNYFLSRNFAKPIIISTPDQLMHFVFRYKGFEKYYATALYSRLVIDELQSYDPITLAFIVQGLEVLAQNGGKFLVMTATFPEFLRERFERMGVEFKTFNTQKKPYHHVQVIDDSIDNYVEKMIELSQKAKVLVVVNTVRKAIELKKKFKEAGLQNVKLLHSRFILKDRKEKEKEIMKFFNSQEKGLWITTQLAEVSLDLDADYLFTELSTADSLIQRIGRCNRKGQKPTNQPNVFIFTKDCSGVGPVYYKHLHESTLRNLKDGLWDWNFKWDLVEKVYSKSALYGTKYWEKFRKAENYIKSLWEGADSLIRSKSEAQDLFRDINAVQVIPEKFREKVESLIQEWEKAKGDFVRRAKLLSDILEYSFSLPAWSIRELEKQKIHDRLGIYYIEGDYNEDTGFVLKPTADTEEVENII
>NZ_CP007028.1|WP_025306061.1|798668_800822_+|type-I-B-CRISPR-associated-protein-Cas5
MECLRVKLYTPTGIFKNPLSIKGIEIYPLPPYSTIIGLIYRAMGRKWNGEYFQISIQGDYQAIYRDYVWFKKHNFKDKELSRLPLQVPILYNLWLLIHIKASEELLNEIENGLKEPKELLFLSGGEYPVKVEEVKRVKCFEKRLSEEETITLNYNAYIPKEFKEKISLSGTGEGVLFSLSYFYKNSQKPKTYSWIDAYYLQKGTEICGSLILDEDNNPVFLAEPTTKEIKKSEGEEYVRFYAGNWLMASACVGVLKVLENAGEDIKKYVEERTLKIPKSLWENLPELYADYLLKDKESVKRSLEDSYRQKAADSNPYNTLIYSRLRDFHSNSPFTNQSHEYIKRLKGVYSENLEEVLGKVKESFLEAYKKLLATTKDLSSICFFCHERHAKNYVDATTFTPLFASLETVRNFIWDPIPICKECEFLLYFASAGFYRYVGKYLFVYVPDDLLETYRLNLILSTEKEIEQEKLSKVWSVVRYVLDLEKQKSSWVLQNIYFVEIEMVGDATANIYSFHISPNLAKAIRKLIDHYPKNLQDIFSEFLFYIYTGRSLYEFLFLMLSGFIRKESYKKLQGGTIESKILQAGRNMKYISQNLLFFINFQEVLNMNEQKGYIDRAFWAGRELKKLYKENESTQKKLEPLTYRLLEAIRRKDKEYFIHNLIRAYLEVEKEIPYLFKEALDDKNFSMIAYAFLIGLNSEEKNKEEQANDYGENSESA
>NZ_CP007028.1|WP_025306060.1|797632_798688_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKGMLTLTLITQRATSLNYGENIGNVSILKKLSLGDNSQITYVSDKALKYDIRRKGKEEKGWRLLDEKVKELIEGSIVQVPKETKGKKKKSKESTETEMQDVLDVDEFAKKLIREYQEFDLFGGLFTNLIRANGESIGLSYGDSVKRTAPVKITYAYSTSKFQGDMDFMNNIEAYNRYIRHIEQKDAQVITQSEQHTAHYYYTIAIDLDRIGVWETENGTEEVIPAEEKAKRVKDLLDIIRTLSRQIRGRYENLSPIFVIGGIYKVKNPFFMGCVSAKETEDGKLLLDVNRLLDCKGIIPEEERANTLCGLLSGFFANEQEIREKLNCKSVEEVFEELKNKVGEIYGVSKG
>NZ_CP007028.1|WP_025306059.1|797380_797572_+|hypothetical-protein
MEIAYKDFHRKMAPFREESLEDILENQVNQWIRLNNIQVINVETLWERNSHVSVGVRVWYIKK
>NZ_CP007028.1|WP_025306058.1|796735_797377_+|hypothetical-protein
MKKLMLIMALFIATPVVKSQENIYLVPERANMRINVAVQIAKQLKDRGYDKIAVVYMNTSDLCALTAASLVASLKTLGVEAYYLKGADPDLPSKIRNLGANWIYLAYFGERPYEEVQGALNQDLRILASGFERANLIVHPSTLGLGFLAGVLVDDKIGEFLSRSNIKGFTVQQGKAEMVSVKVKDLEITIEPEPLPKKETPKTPKTPTRKRTR
>NZ_CP007028.1|WP_025306068.1|807594_807912_+|hypothetical-protein
MSKEFELGIGLLKKIYTELQALSTAEDKRQVKELTQAIINPLVAGAYQIKVGEGPQKDKLLEILFPLIRELRDMQNLESIRALAGELVNALNAIEAEVATQEGSS
>NZ_CP007028.1|WP_025306069.1|807911_808706_+|3-methyl-2-oxobutanoate-hydroxymethyltransferase
MKTTIRTLFNKKEKGQKITMISTYDYLSAKLCEQVGIDCILVGDSLGMVFQGKDSTLEVTVEEMIYHTKAVRRGAKESFIIADMPFMSYQVSVEKAIENCGRLIKEGGANAVKLEGGEEIADLVYKLVRIGIPVVGHLGFTPQKINTIGGYRVVGREEEAERVKKDFKILEEAGAFMIVLEAMPTELAKELTESARSITIGIGAGPYCHGQVLVFYDLVGLVEDIKPKFVRRYLNSAELFRKALEEFKRDVESGSFPSEEESYG
>NZ_CP007028.1|WP_025306070.1|808698_810399_+|type-II/IV-secretion-system-protein
MDEAKLLEFLSRLGYITKDQVQKAISSKEKNEDIITTLLRLGFMDDEKLLDFYTKYTPQKLWKGDLKSINIPAEILNKIPQDILKKHLIAPVSYQDGKLTIVTVNPFNQSAINELRFASKIDNIVSYAAPKKTIEDILNRLYPQTQDILEEISEVSEIEIETSESELSLDTISKEAGEAPIVRLANFLIMEAVNLGASDIHVEPQEKKLVVRYRVDGVLRIFHEFPINIKDALTARLKIMANLDISERRKPQDGRIRAKIGNKKVDLRVSTVPVVYGEKIVMRIQEAEKYLSVRLEDLGFEPDDLEKFRKAIWTPWGMILVTGPTGSGKTTTLYAALMERNKPDVNIMTAEDPVEVSIPGLNQVQVNERIGLTFATVLRAFLRQDPDIILIGEIRDTETAEIGIRAALTGHLVFSTLHTNDAPSSITRLVDMGIEPFLVGSSIILVVAQRLVRKLCPKCKLVDDTPKEALVRLGVLKSLDENITIYKANPKGCDECKGTGYKGRTAVHEILEVDEEMRKLIVRGATAEDIRELAKRKGMRTIYEAGILKVRRGITDIAEVERVLAK
>NZ_CP007028.1|WP_025306071.1|810395_810776_+|acyl-CoA-thioesterase
MIYRRRVQFYETDAQGVMHHSNYFRLFEEARGELLRSLGIPYSTLREEGYEVVLLEAECRFKKPIFYDEEVCVEIKLDSMDRYFFSFSYRVSVEDSLRAEGRTKHCFVKGGRLTSIPKKVRELFDV
>NZ_CP007028.1|WP_025306072.1|810768_811188_+|hypothetical-protein
MFERLILSLYTGTLFSIVFLVAPILLRTEKDKNLAGRFYGRILWRFYKLAFFTLLFYLLIADEKVYALLLMVGLALNVGLSFYLKNLKRELGDIDQIDYNHPKRIKFRRLSLLSTALLFINFLLSTFILIKTFGGADGV
>NZ_CP007028.1|WP_038532119.1|811177_811690_+|translation-initiation-factor-IF-3
MEYRINRQIRAKEVRLIDQDGKQIGIVPLQEALRIAEERGLDLVEVAPNANPPVCKLLDYGKFLYELKKKEKEARKKQREHSMEVKDINLSLRIDEHDLKVKLKHMREFLEDGDKVRVRIRFRGRENAHPELGDRLVNRIVEELSDCGQLEGPPKKEGNFLTFALLPKKK
>NZ_CP007028.1|WP_025306074.1|811792_812530_-|ABC-transporter-permease
MLKVFEEIGKATLLTLWAIFFLFKNPPRLTHFIKQLTYLGAETTPVVLITSLFSGGVIALQTYSTFHRFNAEFLIGAVVALSMGRELAPVLTALMVVARVGSAMTAQIGTMRITEQIDALEVMGIDPRSYLITPRIVAGTLGVPMLTVLSNIAGIFGGWFVAVKLFGVNEYLFWEKMKDLTELHDFLGGLYKATFFGFIITAVSCYFGFYTRGGTEGVGRATTNSVVASSMLVLISDYFLTAIIF
>NZ_CP007028.1|WP_025306075.1|812513_813677_-|chorismate-synthase
MPIRFLTAGESHGRGLVCIIEGIPANLELSSEYINRELERRQRGYGRGGRMKIEKDRVQILSGVRFGKTLGGPIALFIENKDWENWKEKMAVEGERPETAVPFTRPRPGHADLAGGIKYNQRDLRNILERASARETACRVALGAVCKRFLEELGVFVGSYVVSIGPLCPPIEEQDLIKRHQLAEQSEVRFPDPSKDKEFMELIDRAKEMGESLGGVFEVFAVGVPPGLGSHVHWDRKLDGRIAQAMMSIQAIKGVEIGLGFEAAKRFGSEVHDEIGYREGEGYFRYSNNLGGLEGGITNGMPIIVRCAMKPIPTLTKPLRSVDVLTKEEVRAGKERTDVVAVPAASVVGESALALVLADAFLEKLGGDFMEEVKERYRIYLEHVKSF
>NZ_CP007028.1|WP_025306076.1|813681_813882_-|50S-ribosomal-protein-L28
MAKCYVCGKTTKVGRSVTFSGERNPRLFKANLHRVKAVLEDGTVKRIYVCTKCLKAGKVVKAVKFS
>NZ_CP007028.1|WP_025306077.1|814157_814736_+|transposase
MKEKVLGCDVSKDYIILHDGNQAYKLSLENFKSLQKLVNNSIVVLEQTGAYGLRWGQVLEDLGAKVYIADGKDFKNFKLYQAVRKKDDYTDAYYLRLFFFERPKRVWRFNKELAHLRALIRQHMRNEKDITKHANRLSQYLAVIFPTKNYCDLDRKKFLKALDEIEQELKQTPHALSGLALMELNKLRVVLD

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Crispr_ID: NZ_CP007028_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007028_5

859098-860004

Orphan

Consensus_repeat	Method
CTTTCAACTCCACACGGTACATTAGGAAC	PILER-CR
GTTCCTAATGTACCGTGTGGAGTTGAAAG	CRISPRCasFinder
GTTCCTAATGTACCGTGTGGAGTTGAAAG	CRT

13 spacers

The CRISPR arrays of NZ_CP007028_5

>merge|NZ_CP007028|5|859098-860004|PILER-CR,CRISPRCasFinder,CRT
GTTCCTAATGTACCGTGTGGAGTTGAAAGTATCAAAGGGATGGAGAACACGATAACGAAAAGCCTTAAAGGGTTCCTAATGTACCGTGTGGAGTTGAAAGGACAGCATAATATGTTTTCCCTGATCCGGGCACTCCAAAAAGTTCCTAATGTACCGTGTGGAGTTGAAAGACAGACTGTTGCTTTCTTCTGGCAATGGTAGAAGGTAGTTCCTAATGTACCGTGTGGAGTTGAAAGACTTTATACAGGTTTTGGTGGTAAGTATCTTTCAGGTGTTCCTAATGTACCGTGTGGAGTTGAAAGACTTTATACAGGTTTTGGTGGTAAGTATCTTTCAGGTGTTCCTAATGTACCGTGTGGAGTTGAAAGATAAAATCATCAAGGGCTTCAATAAAGACCCTCACATTGTTCCTAATGTACCGTGTGGAGTTGAAAGCAGCAAGAGCAATCCAGCCAACGGGGGAGGCAAGCAGTTCCTAATGTACCGTGTGGAGTTGAAAGTAGCTAAACCCTCCTTAAAACGATAATTCATCACTCGTTCCTAATGTACCGTGTGGAGTTGAAAGCTATTTTTCGTAGTCTTTGCTCCGGCTACCCTACCCGTAATGTTCCTAATGTACCGTGTGGAGTTGAAAGAGCATAGAACCATCTTTGCACCTTCAAGCCTGCAGTTTGTTCCTAATGTACCGTGTGGAGTTGAAAGTCAGGTTCGTAAGTGTTCCTTCTGCTGCTTCAAGCACGTGTTCCTAATGTACCGTGTGGAGTTGAAAGTCAACCTGAACAGTGTGCCCCGTGTTTGCTAAGGTTATTGTGGTTCCTAATGTACCGTGTGGAGTTGAAAGTAAGTAGCAAAAACGCCAAAGTCTATAACATCAACGAGTTCCTAATGTACCGTGTGGAGTTGAAAG

>NZ_CP007028|5|5|859098-860004|PILER-CR
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TATCAAAGGGATGGAGAACACGATAACGAAAAGCCTTAAAGG
GTTCCTAATGTACCGTGTGGAGTTGAAAG	GACAGCATAATATGTTTTCCCTGATCCGGGCACTCCAAAAA
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ACAGACTGTTGCTTTCTTCTGGCAATGGTAGAAGGTA
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ACTTTATACAGGTTTTGGTGGTAAGTATCTTTCAGGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ACTTTATACAGGTTTTGGTGGTAAGTATCTTTCAGGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ATAAAATCATCAAGGGCTTCAATAAAGACCCTCACATT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	CAGCAAGAGCAATCCAGCCAACGGGGGAGGCAAGCA
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TAGCTAAACCCTCCTTAAAACGATAATTCATCACTC
GTTCCTAATGTACCGTGTGGAGTTGAAAG	CTATTTTTCGTAGTCTTTGCTCCGGCTACCCTACCCGTAAT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	AGCATAGAACCATCTTTGCACCTTCAAGCCTGCAGTTT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TCAGGTTCGTAAGTGTTCCTTCTGCTGCTTCAAGCACGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TCAACCTGAACAGTGTGCCCCGTGTTTGCTAAGGTTATTGTG
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TAAGTAGCAAAAACGCCAAAGTCTATAACATCAACGA
GTTCCTAATGTACCGTGTGGAGTTGAAAG

>NZ_CP007028|5|5|859098-860004|CRISPRCasFinder
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TATCAAAGGGATGGAGAACACGATAACGAAAAGCCTTAAAGG
GTTCCTAATGTACCGTGTGGAGTTGAAAG	GACAGCATAATATGTTTTCCCTGATCCGGGCACTCCAAAAA
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ACAGACTGTTGCTTTCTTCTGGCAATGGTAGAAGGTA
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ACTTTATACAGGTTTTGGTGGTAAGTATCTTTCAGGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ACTTTATACAGGTTTTGGTGGTAAGTATCTTTCAGGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ATAAAATCATCAAGGGCTTCAATAAAGACCCTCACATT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	CAGCAAGAGCAATCCAGCCAACGGGGGAGGCAAGCA
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TAGCTAAACCCTCCTTAAAACGATAATTCATCACTC
GTTCCTAATGTACCGTGTGGAGTTGAAAG	CTATTTTTCGTAGTCTTTGCTCCGGCTACCCTACCCGTAAT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	AGCATAGAACCATCTTTGCACCTTCAAGCCTGCAGTTT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TCAGGTTCGTAAGTGTTCCTTCTGCTGCTTCAAGCACGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TCAACCTGAACAGTGTGCCCCGTGTTTGCTAAGGTTATTGTG
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TAAGTAGCAAAAACGCCAAAGTCTATAACATCAACGA
GTTCCTAATGTACCGTGTGGAGTTGAAAG

>NZ_CP007028|5|4|859098-860004|CRT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TATCAAAGGGATGGAGAACACGATAACGAAAAGCCTTAAAGG
GTTCCTAATGTACCGTGTGGAGTTGAAAG	GACAGCATAATATGTTTTCCCTGATCCGGGCACTCCAAAAA
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ACAGACTGTTGCTTTCTTCTGGCAATGGTAGAAGGTA
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ACTTTATACAGGTTTTGGTGGTAAGTATCTTTCAGGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ACTTTATACAGGTTTTGGTGGTAAGTATCTTTCAGGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	ATAAAATCATCAAGGGCTTCAATAAAGACCCTCACATT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	CAGCAAGAGCAATCCAGCCAACGGGGGAGGCAAGCA
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TAGCTAAACCCTCCTTAAAACGATAATTCATCACTC
GTTCCTAATGTACCGTGTGGAGTTGAAAG	CTATTTTTCGTAGTCTTTGCTCCGGCTACCCTACCCGTAAT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	AGCATAGAACCATCTTTGCACCTTCAAGCCTGCAGTTT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TCAGGTTCGTAAGTGTTCCTTCTGCTGCTTCAAGCACGT
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TCAACCTGAACAGTGTGCCCCGTGTTTGCTAAGGTTATTGTG
GTTCCTAATGTACCGTGTGGAGTTGAAAG	TAAGTAGCAAAAACGCCAAAGTCTATAACATCAACGA
GTTCCTAATGTACCGTGTGGAGTTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007028.1\|WP_025306119.1\|858156_858591_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NZ_CP007028.1\|WP_025306127.1\|867299_867893_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP007028.1\|WP_025306128.1\|868176_868932_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NZ_CP007028.1\|WP_025306125.1\|864500_865625_+\|hydrogenase-formation-protein-HypD	unknown	unknown	gnl\|CDD\|237892
NZ_CP007028.1\|WP_025306110.1\|850708_851152_-\|thiosulfate-oxidation-carrier-protein-SoxY	unknown	unknown	gnl\|CDD\|275281
NZ_CP007028.1\|WP_025306130.1\|869474_870119_-\|energy-coupling-factor-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|183376
NZ_CP007028.1\|WP_156916199.1\|860070_861171_+\|KamA-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224426
NZ_CP007028.1\|WP_025306126.1\|865621_867310_+\|hydrogenase-maturation-protein	unknown	unknown	gnl\|CDD\|187719
NZ_CP007028.1\|WP_025306111.1\|851163_851577_-\|thioredoxin-fold-domain-containing-protein	unknown	unknown	gnl\|CDD\|239249
NZ_CP007028.1\|WP_025306113.1\|851876_852806_-\|histone-deacetylase	unknown	unknown	gnl\|CDD\|212518
NZ_CP007028.1\|WP_025306129.1\|868924_869485_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306114.1\|852802_853942_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NZ_CP007028.1\|WP_025306116.1\|854493_855945_+\|menaquinone-biosynthesis-decarboxylase	unknown	unknown	gnl\|CDD\|163413
NZ_CP007028.1\|WP_025306117.1\|855960_857352_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|223112
NZ_CP007028.1\|WP_025306121.1\|861170_861953_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|377085
NZ_CP007028.1\|WP_025306115.1\|854070_854490_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306112.1\|851669_851876_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306124.1\|864271_864514_+\|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	unknown	unknown	gnl\|CDD\|376549
NZ_CP007028.1\|WP_025306122.1\|861974_863651_+\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|237783
NZ_CP007028.1\|WP_025306118.1\|857299_858115_-\|3-deoxy-8-phosphooctulonate-synthase	unknown	unknown	gnl\|CDD\|235363

Protein	Function_ID	Function_description	E-value
NZ_CP007028.1\|WP_025306119.1\|858156_858591_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	7.46837e-32
NZ_CP007028.1\|WP_025306127.1\|867299_867893_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.22746e-14
NZ_CP007028.1\|WP_025306125.1\|864500_865625_+\|hydrogenase-formation-protein-HypD	gnl\|CDD\|237892	PRK15062, PRK15062, hydrogenase isoenzymes formation protein HypD; Provisional.	0
NZ_CP007028.1\|WP_025306110.1\|850708_851152_-\|thiosulfate-oxidation-carrier-protein-SoxY	gnl\|CDD\|275281	TIGR04488, sulfur_oxidation_protein_SoxY, thiosulfate oxidation carrier protein SoxY. Members of this family are bona fide SoxY, the sulfate carrier protein with the GGCGG ir GGCG swinging arm C-terminal sequence. The Cys in the swinging arm is the residue to which the inorganic sulfate moiety becomes covalently attached. In some species, a closely related paralog occurs as well (TIGR04487), with a swinging arm sequence AACIE. More distantly related forms have an additional C-terminal SoxZ-related domain. All members are periplasmic and have an N-terminal twin-arginine translocation (TAT) signal sequence.	4.2262e-55
NZ_CP007028.1\|WP_025306130.1\|869474_870119_-\|energy-coupling-factor-ABC-transporter-permease	gnl\|CDD\|183376	PRK11909, PRK11909, cobalt transporter CbiM.	1.14321e-52
NZ_CP007028.1\|WP_156916199.1\|860070_861171_+\|KamA-family-radical-SAM-protein	gnl\|CDD\|224426	COG1509, KamA, Lysine 2,3-aminomutase [Amino acid transport and metabolism].	2.6706e-164
NZ_CP007028.1\|WP_025306126.1\|865621_867310_+\|hydrogenase-maturation-protein	gnl\|CDD\|187719	cd08650, FMT_core_HypX_N, HypX protein, N-terminal hydrolase domain. The family represents the N-terminal hydrolase domain of HypX protein. HypX is involved in the maturation process of active [NiFe] hydrogenase. [NiFe] hydrogenases function in H2 metabolism in a variety of microorganisms, enabling them to use H2 as a source of reducing equivalent under aerobic and anaerobic conditions. [NiFe] hydrogenases consist of a large and a small subunit. The large subunit contains [NiFe] active site, which is synthesized as a precursor without the [NiFe] active site. This precursor then undergoes a complex post-translational maturation process that requires the presence of a number of accessory proteins. HypX has been shown to be involved in this maturation process and have been proposed to participate in the generation and transport of the CO and CN ligands. However, HypX is not present in all hydrogen-metabolizing bacteria. Furthermore, hypX deletion mutants have a reduced but detectable level of hydrogenase activity. Thus, HypX might not be a determining factor in the matur ation process. Members of this group have an N-terminal formyl transferase domain and a C-terminal enoyl-CoA hydratase/isomerase domain.	2.77304e-88
NZ_CP007028.1\|WP_025306124.1\|864271_864514_+\|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	gnl\|CDD\|376549	pfam01455, HupF_HypC, HupF/HypC family.	1.99844e-30
NZ_CP007028.1\|WP_025306113.1\|851876_852806_-\|histone-deacetylase	gnl\|CDD\|212518	cd09992, HDAC_classII, Histone deacetylases and histone-like deacetylases, classII. Class II histone deacetylases are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. This group includes animal HDAC4,5,6,7,8,9,10, fungal HOS3 and HDA1, plant HDA5 and HDA15 as well as other eukaryotes, archaeal and bacterial histone-like deacetylases. Eukaryotic deacetylases mostly use histones (H2, H3, H4) as substrates for deacetylation; however, non-histone substrates are known (for example, tubulin). Substrates for prokaryotic histone-like deacetylases are not known. Histone acetylation/deacetylation process is important for mediation of transcriptional regulation of many genes. Histone deacetylases usually act via association with DNA binding proteins to target specific chromatin regions. Interaction partners of class II deacetylases include 14-3-3 proteins, MEF2 family of transcriptional factors, CtBP, calmodulin (CaM), SMRT, N-CoR, BCL6, HP1alpha and SUMO. Histone deacetylases play a role in the regulation of cell cycle, cell differentiation and survival. Class II mammalian HDACs are differentially inhibited by structurally diverse compounds with known antitumor activities, thus presenting them as potential drug targets for human diseases resulting from aberrant acetylation.	2.36957e-155
NZ_CP007028.1\|WP_025306118.1\|857299_858115_-\|3-deoxy-8-phosphooctulonate-synthase	gnl\|CDD\|235363	PRK05198, PRK05198, 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional.	3.52234e-167
NZ_CP007028.1\|WP_025306116.1\|854493_855945_+\|menaquinone-biosynthesis-decarboxylase	gnl\|CDD\|163413	TIGR03701, mena_SCO4490, menaquinone biosynthesis decarboxylase, SCO4490 family. Members of this protein family are putative decarboxylases involved in a late stage of the alternative pathway for menaquinone, via futalosine, as in Streptomyces coelicolor and Helicobacter pylori. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	0
NZ_CP007028.1\|WP_025306117.1\|855960_857352_+\|amidophosphoribosyltransferase	gnl\|CDD\|223112	COG0034, PurF, Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism].	0
NZ_CP007028.1\|WP_025306121.1\|861170_861953_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	2.32955e-06
NZ_CP007028.1\|WP_025306111.1\|851163_851577_-\|thioredoxin-fold-domain-containing-protein	gnl\|CDD\|239249	cd02951, SoxW, SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide fixation during autotrophic growth and the respiratory electron transport chain. It is unclear what the role of SoxW is, since it has been found to be dispensable in the oxidation of thiosulfate to sulfate. SoxW is specifically kept in the reduced state by SoxV, which is essential in thiosulfate oxidation.	2.95962e-16
NZ_CP007028.1\|WP_025306128.1\|868176_868932_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.69976e-90
NZ_CP007028.1\|WP_025306122.1\|861974_863651_+\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|237783	PRK14667, uvrC, excinuclease ABC subunit C; Provisional.	0
NZ_CP007028.1\|WP_025306114.1\|852802_853942_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0

>NZ_CP007028.1|WP_025306119.1|858156_858591_-|Hsp20/alpha-crystallin-family-protein
MRRGLLVWRPFEELERIRRDFDRLMEEFFAKEEPVERVFAPALDVYETDSEVVVKAELPGVKKEDVEVLIRDNSLIIKGEKKEEREEKTETYHRVERVYGKFERVVALPAEVKLEGIKAEFKDGVLEIRLPKEKTSKEVKIEIQ
>NZ_CP007028.1|WP_025306118.1|857299_858115_-|3-deoxy-8-phosphooctulonate-synthase
MLIIAGPCVIENEDVVFRVAEELSRLSLEFPEFDFYFKSSFDKANRSSIRSFRGPGLEEGLKVLEKVKKEFGLKITTDVHETWQVEPTAQVVDMLQVPAFLSRQTDLVLACAKSGKPVNVKKGQFMAPWDAKNVVEKLKAGGAVDYYITERGVSFGYNNLVVDFRSLVIMSQFTKVIFDATHSVQLPGGAGDRSAGQREFVLPLIRAAVAVGCDGIFMEVHPDPDRALSDGPNMLPLKDLRKALETIRVIKDAVSTLSSEPPLLPPKDTAH
>NZ_CP007028.1|WP_025306117.1|855960_857352_+|amidophosphoribosyltransferase
MCGIFGIFGVENAEKYAFFGIYALQHRGQESVGIAVSDFENIKVVKKEGLVLSAIKKEDLEQAKGYLAIAHVRYATAGRSGAFNAQPFLKKTPIGEVAVAHNGNLINFKELKDELLREGEAFEYDSDTELFLSLLCKGTYTPEGLKLHPEDEQLLPYFFYVLKRVQGAYSVLFLLKDRLIAIRDPYGFRPLLMGRLKDAILFASESCAFDILSGEFWREVKPGEVVVVSKSGIRSYFPFSSSKRAMCIFEFVYFSKPESYIFNEWVYNVRKKMGEVLAQEDELIADVVVPVPDSGVVPALGYSQRKGIPLELGLIRNHYVGRSFIEPTQELRDIKVLMKFNPNPAVLKGKRVVVIDDSLVRGTTSKKIVSMLRKAGAKEVHMRIASPPVIGPCYYGIDTPTKEELIATKFSVQEIAEFIGADSLKYLSLEGLKSCVEDPEDFCTACFSGQYPLEVKEEVQRIR
>NZ_CP007028.1|WP_025306116.1|854493_855945_+|menaquinone-biosynthesis-decarboxylase
MPYKDLREFLRRIEKEGELARIREEVSPILEITEITDRVCKMPKGGKALLFERVKGYSIPVLTNMLGSEKRVKLALGYENLEDIGWKLYKLLRPEIPHTFLDKLKKLPELKKLNDALPKVVKDGPIREVVRREKIDVLEFPILQCWPEDGGRYITFGQVITKDPESGIRNVGLYRVQVLSPTELALHWQIHKDGNHHYWKAKRLKKKLEVAIAIGGDPVLSYVASAPLPPEVDEYLFAGLIREEGVELIKGITVDLEYPAHAEIVIEGYVDPEEPLVDEGPFGDHTGFYTPVDKYPKMHITAILHRRDPIYVATIVGKPPQEDKYIGWATERIFLPLIKFNLPEVVDYHLPAEGCFHNFCFVSIKKRYPGHAFKVAYALLGLGLMSLTKHVVVFDEDINVHDFGEVLWAWGNNVDPSRDVQILKGPIDVLDHSTNEVGFGGKMIIDATTKWKEEGYTRQWPKVIEMSEEVKKRIDAIWDKLNL
>NZ_CP007028.1|WP_025306115.1|854070_854490_+|hypothetical-protein
MAGVWEEALVEEAIYLIAHLAQSEQHLMEIEGETKLEDLMPIIDGLRNKRKVVGDVLFSVLRIEGEKEKEEFRTKLESLWCSLKHLAMALVHCDETVEKLIRRLECHLQGGDMEKAKELSEKVKELYKVRQSIRNFMKE
>NZ_CP007028.1|WP_025306114.1|852802_853942_-|methionine-adenosyltransferase
MHIRMAESPTEGHPDKVADLIADALLDEFLRKDPYSRVSLEVMVISGMTFVAGHVSTEGYVDIPGIVRSTIKEVGYNRPELGFDADASAVIISIEEQSPEIVLGLSQEGAGDTAVVIGYACNETESYMPLPISLAHFLSKKLADLRKTGRAPFLRPDGKALVTVAYEGTKPLFVKDIILFAQHDPDVSLEKLKEYLVEEVVKKVVPSRYISKETRILVNPSGRFVLGGPVADVGQTGRKIVSDAYGDTAYSGGSAFSGKDPTKTDRSASYLARMMAKHVVAGGFAERCLVQLAYAFGVSEPIAFDIETYGTEKVEKERIKEALREIFPLNPRRMIEFLDLRKPIYKKTACYGHFGKEELPWEKLTKLEELKERLGGGIQ
>NZ_CP007028.1|WP_025306113.1|851876_852806_-|histone-deacetylase
MKTGIVYDNIYLEHNERGHPENKDRLISIVQEIENSGLFKHLQKIKPRRATVEEVSLNHDISYIQEIHDFCASGGGYLDPDTYANSMSYETALYAVGGVLEGIDRLLSGEVSAVFCAIRPPGHHAERSRAMGFCLFNNIAIGAHYLLKKGFDRIFIIDFDAHHGNGTQKSFYEEDRVFYFSTHEYPFYPGTGSAEEKGVGKGYGYTYNVPLSAGTGDAEYEDIYTNLVPKLIYEYSPQFLLVSAGYDIHKDDPLTFLNVSTQGVAKIVESILKTAKRMDLPVLFALEGGYNLKALGECVAITIEKMLEA
>NZ_CP007028.1|WP_025306112.1|851669_851876_-|hypothetical-protein
MLKKVKHYLFQFLSFVLVAYGFYLLFLLLLDTFLRINRTLAFPISALITLVLIALTVLYYVKHKRLPL
>NZ_CP007028.1|WP_025306111.1|851163_851577_-|thioredoxin-fold-domain-containing-protein
MINKLINSLFLLLFAWVGFALANPVEQTIQRAVSENKLIAFYFKSQFCPYCSQVEEFVFSDEEVSKKLRNFLFVELDIRSEEGSKLARRFGVPGTPTLVIYDPKQDRVVSLIFGSRPKGDYLNTINKACKLYSIKTC
>NZ_CP007028.1|WP_025306110.1|850708_851152_-|thiosulfate-oxidation-carrier-protein-SoxY
MNRRKFLLLSAVAVAGLTFAPAIKPAFAASKLEEEIKKRLGVELKAIKETAEIKLTAPTIAESGANVPITVEADIPVDKVERLWIFVDKNPIPWVTDVKFTPQNGQVFLSTRIKMGETSNVRAILQLKDGTFVMATKEVKVTAGGCG
>NZ_CP007028.1|WP_156916199.1|860070_861171_+|KamA-family-radical-SAM-protein
MIFQMRVKKELWRSYHWQIQNRVKTQEELERFLRLLPEEIEGIKRTQGIYPMAITPYYLSLIDPQDPQDPIRLQAIPRAVEVDERVQCHGEPDALREEGEIPGLTHRYPDRVLVQTTTFCAVYCRHCMRKRIFSQGERAISVEQIKQITQYIKAHPEIREVLLSGGDPLTLSYEKLELLLSEIRKIPHVEIIRIGTRLPVLAPQRFFDQKLLDILEKYSPIWISTHFNHPKEITPEAQEAVENILRRGIPVLNQTVLLKGVNDDPQTMLELMRSLIRIKVKPQYLFHCDPIKGAVHFRTTVEKGLEIMDYLRGRISGYAIPTYAIDLPGGKGKVPLLPQYLLAKEGTRHVFRSWQGELVEYDIQEF
>NZ_CP007028.1|WP_025306121.1|861170_861953_+|YihY/virulence-factor-BrkB-family-protein
MVKSRLLALFYSLKEIFLGDVGLYASALTLRFLMVISSLLLFFGFLASFFPFLNQEKITQVISQLTPTYAEVLINKLLKIYKHREIGSVFSFFISYFFLVGYAKTLAKAISRVLKEDIKLKETLLWIFIPVYLLGFSVFILVGSAVLSLLQSFIPKSLSFALSLSKLLLFLPLIYFMYWFFLRDTLKPMRILETSVLFLVFLMLLNFIFGKFFIKLIGLNPLYAVLGSLLSFLVWLELTFSFLLGAIIYAKRLEPNLKGG
>NZ_CP007028.1|WP_025306122.1|861974_863651_+|excinuclease-ABC-subunit-UvrC
MLELIKSAPTQCGVYLFKKGNKVLYVGKAKNIRERLLQHYKQAQENKKEYAIVNSSDRIDWILTRNEYEALVLEVDLIQLHKPKYNVLHKHGGGYPVLLLTEDEFPTIKVVRGSEHEGKLFGPFFTAKRAYRVKRLIHKLFKLRTCDPMPTRASPCMDYHLGLCSGPCAGLISKEDYSLAVKSAQSMLSGEVSEVLPELYQRMEEHMERLEFEKCALIRDQIRALEKLSLGQSVSGLPYQRADLFYRIGRLLGVFLIRSFKLVDKEVFLLETEEELEETIIGFYYSNPLPEVLLLNFELSEEVKRWLSERGKVEIVQKIDQSLEELVKENLHHYMPPELWQEEFLKVLKIPPPRIIEGFDVSHFYGGYTVASCVVWEEGTMNKKRYRRYRIKTVNQIDDYASLEEVLSRRARRLKEGEETMPDLWLIDGGLGQLSVAIRVRDRFGLPIKVVSLAKEEEILLTEWGQRVRLKEHPILYRIFGQIRDEAHRFALSYNRKLRLKEGLKDILDRIKGIGEVKKKIIYNNFENLYELLKAEDRHLKKLGIDPSIKQEIEKYLT
>NZ_CP007028.1|WP_025306124.1|864271_864514_+|HypC/HybG/HupF-family-hydrogenase-formation-chaperone
MCLAIPSQIEKINEDNTAIVNTMGVRRLVSLELLGEPVKEGDWVLIHVGFAISKLNEEEALKALELFEEILEMEEQYENY
>NZ_CP007028.1|WP_025306125.1|864500_865625_+|hydrogenase-formation-protein-HypD
MKTINLKAFRDSEKLKGLEYSIKKFVEKIGRTINIMEFCGGHTHTIIKYGIDQLLEGYIRFIHGPGCPVCVIPSSRIDLAIEIAGQKDTILCTYGDLLRVPSSNRKTLLDLRAEGYDVRMVNSSLEALNIALSEKGKRVVFFAIGFETTTPQTAVLLLKAKELGLKNLYVVSNHVITPAAIQHILNSPEIRDIGKVEIDAFLGPGHVSTIIGTRPYEYFSEEFLKPVAICGFEPLDVMQGVWLVVNQIARGEAYVVNQYTRFVSREGNIKAQKLVSEVFELRKVFEWRGLGIVPYSALKIRKEFEAFDGEKSFDVKLPPPKEHPACICGKVIRGVALPTECKLFGTVCTPQNPIGSCMVSSEGACAAYFKYKRL
>NZ_CP007028.1|WP_025306126.1|865621_867310_+|hydrogenase-maturation-protein
MRILFLCYRFNSLSQRLYCELTERGHEVSIELDVHPELTIEAVNNYKPDLIIAPFLKRKIPREVWSRVKTLVIHPGPPGDRGPSALDWAILRQEKEWGVSLLEAVDEYDAGPVWSYRTFPMRKARKSSIYRNETTDGAVESVLEIIEQLLEGKEPKKLYPKGIWNPRMDQSYRYVNWSEDPTGEILRKVYASDSQPGALARLGDDEYYIFNAYREDYLKGKPGEIIAVRDEAICIGTLDGAVWITHLREKGKDSIKLPAARVIGHLLKNIREESIKPWEIVDFATYREIIYEEEGGIGHIFFNFYNGAMSTEQCERLLETFRYAKKRPVKAIVLWGQEDFFSNGMNLNTIENAESPADESWRNINAMDDLCEEILRTTDKLTVACMQGNAGAGGVFLALTCDLVYARESVVLNPHYKNIGNLYGSEFWTYTLPKRVGWEMGKKIMDNRMPISAKQAFKIGLIDKVFKGTQKEFREKVIRELKDFIDSRDYELFIENKKTQRLKDELQKPLSEYRKEELEMMKLNFYGFDPSYHVARYYFVRRIPPFRTPPYLAIHRRLKSKP
>NZ_CP007028.1|WP_025306127.1|867299_867893_-|TetR/AcrR-family-transcriptional-regulator
MGRRLLKEKKKLDIIRTACRLFAEKGYYNTVIPDIAKALNMSVGNIYNYFESKEELAKEIMITVSNWVAERLRKINQENISTKEKIYKYTEEFFKIALEEPELINYFLRVFLVNREIFKEGCEGFACVGEVVAEVMILLSDGIEKGELRNQSFFPAFTTIMGTLGGMVFLHNEGLLEKPLMEYTHEVATNIWNALKA
>NZ_CP007028.1|WP_025306128.1|868176_868932_-|ABC-transporter-ATP-binding-protein
MIELRNVWFSYDGEFVLKDINLKVEKGERIVVLGINGSGKSTLLKLLNALLFPTKGTYLYKGKNIEKNAFKDKNFIKAFRKEVVLLFQNPDAMIFNPTVYDEIAFGLRQLGFEEKVVKERVLYWAEVFGLTQYLNKPPFILSGGQKQKLCLACLLVLEPEVLLLDEPTANLDPKSTGWLIDFLNELKGVTTITSTHNLSLAPELGNRLIVLREGGSIIYDGEAEAFLKDQEKLINAGLVHKHKDKPYYHLH
>NZ_CP007028.1|WP_025306129.1|868924_869485_-|hypothetical-protein
MKDKALFSFYLLFIFLLSFGSSLKILAMSTSLLLLALLVLPLEKKIDILRKAFYVCLLFNLLVSFTYFLIGLLSGQNRWEYLVMISLRSFSIALATFIAFRLINIYKVFDFSKSVSFLMIIVSSHIFTYLRLFEEFKNALKSRTIGHIGSNVKMVFISRLLEFFFEKSIRTSEELYQAMKSRGFYD
>NZ_CP007028.1|WP_025306130.1|869474_870119_-|energy-coupling-factor-ABC-transporter-permease
MHIPDGFVAPQIYLPAYILDISLLAYSIRRIKRSLNERAIPYLSSVSLLSFVISSITIPLPGGTSVHGTGIPILSILFGPWVAFVSYSLILFLQAVLFGEGGITTFPINSISMGFVGSFAAFFTYKALSIFKEEVSIVISSFVSVMLSALLIATILGIHPYLFKKADGSPLYFPFGLYITIPAILVPHIFVGLGEGLLSSIAIKVLNRRLKVER

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Crispr_ID: NZ_CP007028_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007028_6

906220-906914

TypeI-B

Consensus_repeat	Method
GTTTCAATCCCCTATAGGCACTT	CRISPRCasFinder
GTTTCAATCCCCTATAGGCACTTAATAAAC	CRT
GTTTCAATCCCCTATAGGCACTTAATAAAC	PILER-CR

10 spacers

TnpB_regular.1,cas3,cas5,cas7,cas8b1,cas6

The CRISPR arrays of NZ_CP007028_6

>merge|NZ_CP007028|6|906220-906914|CRISPRCasFinder,CRT,PILER-CR
GTTTTAATCCCCAATAGGCACTTGATAAACATACAAGGCAGTGGTGCAGAACTCTGCAAAAAAGCTAGTTTCAATCCCCTATAGGCACTTAATAAACATGAAGGCATAGACTTTCATCACGCTAACCTCCTGACGTTTCAATCTCCTATAGGCACTTAATAAACCGAATTTGACCCTCTACCTACTGTGCTCCCTGCATAGTTTCAATCCCCTGTAGGCACTTAATAAACAAGCGGGCTTGATAAGCTTGAAGCGAGAATCAAGTTGTTTCAATCCCCCATTAGGTACTTGATAAACTTCGGGAAATTATTTTAGTCAAATTTTCCAGAATGTGTTTCAATCCCTACTAGGTACTTAATAAACCTTCAGGTAAAGATGCTGGATCGGACTCTACAAGTTCGTTTCAATCCCCTATAGGCACTTTATAAACGGTCATTGCCTCCAAATATTTTTTTTTGTGCTGTTTGGTTTCAATCCCCTATAGGTACTTAATAAACCCACCGCACCATCAGGCAGAATGTCTTGTTCAGATAGTTTCAATCCCCTATGGGCACTTAATAAACTTTGTTTGCGAAAGAAAGCGTGGGTGCGGAGGTGTAGTTTCAATCCCCTATAGGCACTTAATAAACTTTGTTTGCGAAAGAAAGCGTGGGTGCGGAGGTGTAGTTTCAATCCCCTATAGGCACTTAATAAAC

>NZ_CP007028|6|6|906220-906907|CRISPRCasFinder
GTTTTAATCCCCAATAGGCACTT	GATAAACATACAAGGCAGTGGTGCAGAACTCTGCAAAAAAGCTA
GTTTCAATCCCCTATAGGCACTT	AATAAACATGAAGGCATAGACTTTCATCACGCTAACCTCCTGAC
GTTTCAATCTCCTATAGGCACTT	AATAAACCGAATTTGACCCTCTACCTACTGTGCTCCCTGCATA
GTTTCAATCCCCTGTAGGCACTT	AATAAACAAGCGGGCTTGATAAGCTTGAAGCGAGAATCAAGTT
GTTTCAATCCCCCATTAGGTACT	TGATAAACTTCGGGAAATTATTTTAGTCAAATTTTCCAGAATGT
GTTTCAATCCCTACTAGGTACTT	AATAAACCTTCAGGTAAAGATGCTGGATCGGACTCTACAAGTTC
GTTTCAATCCCCTATAGGCACTT	TATAAACGGTCATTGCCTCCAAATATTTTTTTTTGTGCTGTTTG
GTTTCAATCCCCTATAGGTACTT	AATAAACCCACCGCACCATCAGGCAGAATGTCTTGTTCAGATA
GTTTCAATCCCCTATGGGCACTT	AATAAACTTTGTTTGCGAAAGAAAGCGTGGGTGCGGAGGTGTA
GTTTCAATCCCCTATAGGCACTT	AATAAACTTTGTTTGCGAAAGAAAGCGTGGGTGCGGAGGTGTA
GTTTCAATCCCCTATAGGCACTT

>NZ_CP007028|6|5|906220-906914|CRT
GTTTTAATCCCCAATAGGCACTTGATAAAC	ATACAAGGCAGTGGTGCAGAACTCTGCAAAAAAGCTA
GTTTCAATCCCCTATAGGCACTTAATAAAC	ATGAAGGCATAGACTTTCATCACGCTAACCTCCTGAC
GTTTCAATCTCCTATAGGCACTTAATAAAC	CGAATTTGACCCTCTACCTACTGTGCTCCCTGCATA
GTTTCAATCCCCTGTAGGCACTTAATAAAC	AAGCGGGCTTGATAAGCTTGAAGCGAGAATCAAGTTG
TTTCAATCCCCCATTAGGTACTTGATAAAC	TTCGGGAAATTATTTTAGTCAAATTTTCCAGAATGT
GTTTCAATCCCTACTAGGTACTTAATAAAC	CTTCAGGTAAAGATGCTGGATCGGACTCTACAAGTTC
GTTTCAATCCCCTATAGGCACTTTATAAAC	GGTCATTGCCTCCAAATATTTTTTTTTGTGCTGTTTG
GTTTCAATCCCCTATAGGTACTTAATAAAC	CCACCGCACCATCAGGCAGAATGTCTTGTTCAGATA
GTTTCAATCCCCTATGGGCACTTAATAAAC	TTTGTTTGCGAAAGAAAGCGTGGGTGCGGAGGTGTA
GTTTCAATCCCCTATAGGCACTTAATAAAC	TTTGTTTGCGAAAGAAAGCGTGGGTGCGGAGGTGTA
GTTTCAATCCCCTATAGGCACTTAATAAAC

>NZ_CP007028|6|6|906553-906914|PILER-CR
GTTTCAATCCCTACTAGGTACTTAATAAAC	CTTCAGGTAAAGATGCTGGATCGGACTCTACAAGTTC
GTTTCAATCCCCTATAGGCACTTTATAAAC	GGTCATTGCCTCCAAATATTTTTTTTTGTGCTGTTTG
GTTTCAATCCCCTATAGGTACTTAATAAAC	CCACCGCACCATCAGGCAGAATGTCTTGTTCAGATA
GTTTCAATCCCCTATGGGCACTTAATAAAC	TTTGTTTGCGAAAGAAAGCGTGGGTGCGGAGGTGTA
GTTTCAATCCCCTATAGGCACTTAATAAAC	TTTGTTTGCGAAAGAAAGCGTGGGTGCGGAGGTGTA
GTTTCAATCCCCTATAGGCACTTAATAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007028.1\|WP_025306172.1\|913846_914584_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379293
NZ_CP007028.1\|WP_025306168.1\|909254_909989_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP007028.1\|WP_025306160.1\|895972_896737_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP007028.1\|WP_169727092.1\|901903_902014_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|372646
NZ_CP007028.1\|WP_169727093.1\|912598_913252_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|224499
NZ_CP007028.1\|WP_038532144.1\|915445_916189_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|143607
NZ_CP007028.1\|WP_025306166.1\|904881_905913_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240017
NZ_CP007028.1\|WP_156916201.1\|902237_903056_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306169.1\|909988_910882_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|187821
NZ_CP007028.1\|WP_025306173.1\|914565_914850_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306167.1\|907003_909262_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP007028.1\|WP_051402152.1\|903099_904755_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	TnpB_regular.1	-	gnl\|CDD\|273793
NZ_CP007028.1\|WP_025306159.1\|895226_895973_-\|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl\|CDD\|381169
NZ_CP007028.1\|WP_025306170.1\|910878_912606_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|378190
NZ_CP007028.1\|WP_038532140.1\|897003_899646_-\|phosphoadenylyl-sulfate-reductase	unknown	unknown	gnl\|CDD\|223233
NZ_CP007028.1\|WP_025306161.1\|896729_897023_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306162.1\|899789_901148_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP007028.1\|WP_025306176.1\|916185_917088_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP007028.1\|WP_025306177.1\|917132_918431_-\|TrpB-like-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|237087
NZ_CP007028.1\|WP_025306163.1\|901101_901605_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP007028.1\|WP_025306172.1\|913846_914584_+\|AAA-family-ATPase	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	7.63045e-53
NZ_CP007028.1\|WP_025306168.1\|909254_909989_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.41491e-42
NZ_CP007028.1\|WP_025306160.1\|895972_896737_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	3.09049e-23
NZ_CP007028.1\|WP_169727092.1\|901903_902014_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|372646	pfam13610, DDE_Tnp_IS240, DDE domain. This DDE domain is found in a wide variety of transposases including those found in IS240, IS26, IS6100 and IS26.	3.30466e-05
NZ_CP007028.1\|WP_169727093.1\|912598_913252_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	9.68208e-34
NZ_CP007028.1\|WP_038532144.1\|915445_916189_-\|hypothetical-protein	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	2.83738e-74
NZ_CP007028.1\|WP_038532140.1\|897003_899646_-\|phosphoadenylyl-sulfate-reductase	gnl\|CDD\|223233	COG0155, CysI, Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism].	4.05919e-116
NZ_CP007028.1\|WP_025306166.1\|904881_905913_+\|hypothetical-protein	gnl\|CDD\|240017	cd04659, Piwi_piwi-like_ProArk, Piwi_piwi-like_ProArk: PIWI domain, Piwi-like subfamily found in Archaea and Bacteria. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs. The central component of the RNA-induced silencing complex (RISC) and related complexes is Argonaute. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the 5' anchoring of the guide RNA and the other, the catalytic site for slicing. This domain is also found in closely related proteins, including the Piwi subfamily, where it is believed to perform a crucial role in germline cells, via a similar mechanism.	1.1064e-30
NZ_CP007028.1\|WP_025306169.1\|909988_910882_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|187821	cd09690, Cas7_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csh2 family.	8.71212e-80
NZ_CP007028.1\|WP_025306167.1\|907003_909262_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.60019e-49
NZ_CP007028.1\|WP_051402152.1\|903099_904755_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	1.01825e-15
NZ_CP007028.1\|WP_025306159.1\|895226_895973_-\|uroporphyrinogen-III-C-methyltransferase	gnl\|CDD\|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	2.01919e-118
NZ_CP007028.1\|WP_025306170.1\|910878_912606_-\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	9.77095e-59
NZ_CP007028.1\|WP_025306162.1\|899789_901148_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.51864e-122
NZ_CP007028.1\|WP_025306176.1\|916185_917088_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.44628e-96
NZ_CP007028.1\|WP_025306177.1\|917132_918431_-\|TrpB-like-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|237087	PRK12391, PRK12391, TrpB-like pyridoxal phosphate-dependent enzyme.	0

>NZ_CP007028.1|WP_025306166.1|904881_905913_+|hypothetical-protein
MRDLENRARIIENTVLKRVSSLGLYIDRLKPIPIPIPTDVKEFSLLPHVGDLEGSNTFLFVLTDASKLDDELYLDIKRDLLEFDIQSQVIYYRTNVGDRYVACNLMLGLLGKTGNYPYFLKDSSNKVFVGIDLSRKARSSNKGIVHAVGTAIIVDTSDGGTITYKNINVPAGGEAVEKAYVKSLANMLYKYKDKFIVIHRDGRMGVDELNAYVEVFSKQFGRENFALVSIIKSGTPRILQINSNIVGNPPKGCAILLSEREAVISTYEVKESFGTHIPLRIKVLYGDYPLNEAIEDVLRLTLLNFSSFTLNKLPATVAFADRIAWYNLHGIGPEDTDGNLFFL
>NZ_CP007028.1|WP_051402152.1|903099_904755_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MVLSIAGSKNFSEEKAHKLYITLECMLEFEKEEEKEKVLALMRRFSSATRYAYKRLLEGVAEKEIEKATQEKHKLNARYVKDAVLIAKQVLKSCMQRGQNPKKLVFGSRELFEKLKKKHLTGKRREKLRQRWEERRYCYLYSRGEKFHKGNLNLRFVNLNNQWHLRINLGNGEYVWAKVVRNAKRHKDKWIDFTWRLLEAEKSGEWFAYNVRLKVRNGKFYAQVSWEEKTVEPVITKAYGVIGIDINAYPFHLALAYVSTDGNLEKFERIDLREMEGKTKNQREHIAWHIARQVVERALENGKAIVVEDLQKVPKGRRGDGLAKLRRKLHKWAYRSVLEKIEVYARSMGVQLIKVNPAYTSIIGKLKYSPMLGIDKDVAGAYVIGRRGLGFEERLPKNYRELLKDKEFLAYAIAKVDERINKLKSELKRETNEYKRNALKERVKRLRKYLELLLSYTRDSGKSEPATQQAVNREMKPMRGRAKSLQKSWRVLSVALAVLLATTCLEWCRDHSPLKRVLISGDWARVAGKGSPSLPGQGTTAQNKCSFIHFG
>NZ_CP007028.1|WP_156916201.1|902237_903056_+|hypothetical-protein
MLYTYKEYEKPFFYDRETIISLVDIGDSFEDDYYVLEKESSNPEYFFSSPQAWSTFINSFANLLMIYKKDTVRISKGIARKYILGTEFIDQRAYLRIDFKYMLFFPETLYRQLERGEQPEIGGKYYTPSRSVATLKEYRKVSVEEYEKLMKEMLPRSSEITKDRWEKGLEKAKQRGYGYIAIVVFDEVDEDDGREYTYPANALVKVRYIEDLDREELQRIRPKSKERWELIERFRDRVASLLREHSIGLDEEPYTKIEYIAPSFEVVDGGGG
>NZ_CP007028.1|WP_169727092.1|901903_902014_+|DDE-type-integrase/transposase/recombinase
MDKTKIKARDRTYYLWLAVDERGLPVSVHLSRRRDS
>NZ_CP007028.1|WP_025306163.1|901101_901605_-|hypothetical-protein
MPKVDIFSEIETFSSCLKFFPQKVESIQIERLGKEKGYISPLWDLAWHDLYLLQLFFESIRIEKLTVNKVWEPHGRADDVPFYIRTAWQYPQPTRRWIMNSGQVILDFAREEVWGENKLIHMEEKRDKLRLMSESFIKGGFDQKSKERAKKNLILLEHIERLPATSF
>NZ_CP007028.1|WP_025306162.1|899789_901148_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MEKLLYTKDPSLRVEGFQKVEELPEELEKAVVLVDIDTVGVSSLPDLKEGGNIPVAITSKSIPGYTIKLVSLGFYDVLRKPIDEERLRRILQRLDGSQKVQRIIYIHRQEEEISGELCKELCSIVGNPEGKMREVLLRVGKAASLDVPVLFVGETGVGKEVFAKALWKTSRRWNGPFVAINCSAVPSELLEAELFGYEKGAFTGAISSKEGLIESAKGGVLFLDEIGDLPLHLQPKLLRVLQEKKVRRLGSTKEIHCDFRLISATNKDLKRLVKEGKFREDLYYRISTVEIYIPPLRERKDDIPLLVDCILQNISRETGKRIVGYTEGFLKKVLSYNWPGNVRELENALTRAVSSCSGVVLQEEDLDIVTQDYEDYSLESLEDALRREVRRLIEGGERNIYYTLMDRLSKAIVREAFSLLKGNYSKTARTLGINRLTLKKMLQEGARCVPRV
>NZ_CP007028.1|WP_038532140.1|897003_899646_-|phosphoadenylyl-sulfate-reductase
MEKEILEINPRERLKAEKHPLDILSELSEIIKKGYEETPEEDLVRLQWYGLYHDKPRVGYFLLRVKVPGGILSARHVEVLGDLAYRFNDYAELTLRQDIQLHYVRLDDLPEVFDRLKSVELFPVGACGDTVRNITTCPLCGVEKYELFDVMDNIRELEGFFHNPENREYFNLPRKFKITISACPYHCNMPEMHDLAFVGTTLEGTEGFAVWVGGGLSSTPRIARKLGIFVERDKVLEVAKAIVDIWKNDPENRKSFVKARFKYMVDRLGVERIKEMLLERLSFVPAALEQEPIPIKRYFHTGLGEQKQKGYYYLGIPIPAGRIKGSQLLKISELMEKFNLSLRITQRQNLVLTDIPEDKIETVKEEIKRLGFNLDVSEARAISVACTSDPFCNYSVGPSKETLLELLEYLEKELGKIEGIAIGVDGCPHACAHHWLNDIGLQATYLRHPDGSVETTYNLVLRGGYGKHAKVGKIIVKKVPLEKLKGYLKNLILAFRNSGFEDFHSFVNSKSDEELISIMSAKAVEDRKLVKITIFGPLTRFSGGLAEIEVSAQTVRSALEFLEKEFEGFRGKLFDDQGHLKPFVKVFLNEEDISYLKGLDTELKEGDHIMLYPALAGGSPTFDELELHELAIEFEDKPPQELISWAIENFHPKLYIAFSGQAEDMVLLDMAWRINPEVRVFTVDTGRLHEETYRLIQEIEERYNIKVEIYFPSAQEVEELVKRHGINCFYKSVELRHLCCHIRKVRPLLRALSQVDAWFTGLRREQWASRQNIMKIEVDHDHGQIVKINPLADWSERQVWEYIKKNNLPYNKLYEMGYRSIGCEPCTRPVAPYEDPRAGRWWWEKDAPKECGMHCSIETGGFEKIADKLIKEDKDGHKSL
>NZ_CP007028.1|WP_025306161.1|896729_897023_-|hypothetical-protein
MAIRVFERVDEKSLIKELTLRGWKEGKFNGKQAMFKEFEAYLWVAVMEECPYFLSLPKEENSRVHSEGMKELMKEVKELSHRLGFSLPVKPGGGYHV
>NZ_CP007028.1|WP_025306160.1|895972_896737_-|sulfite-exporter-TauE/SafE-family-protein
MFEYVALGFFIAFAIGLTGVGAGTLTAPLLILLGLDPAKAVGSALAFSTAVKFPAMLTHALYKNIDYKTLLLMLSGGVPGTLLGSLFLKLFHELLGLDTSGLKKILLLIIGITVLFSVLLNLLMVWKGRRFDLTKYKYLLPVACFLIGVEVGLTSAGAGALGMVLLLYFTKLSPAKAVGVDIAFGLACSLVGGTSHFLQGHTDTGIFIPMSLGGLAGVLLGTHLARTLNPKPLKVAISILLVVIAINLIQKGLS
>NZ_CP007028.1|WP_025306159.1|895226_895973_-|uroporphyrinogen-III-C-methyltransferase
MGKVYIVGAGPGDVELLTLKAYKLIKSADVILYDRLINQEILSLAKPDCELVYVGKEDGKHTVEQEKINELLLRYAHTKDIVVRLKGGDPFVFGRGGEEALFLAQHSVEFEVVPGVSSAIAVPACAGIPLTFRGLSSSFAVITGHEDPRKERSDIDWESLKGINTLVFLMAVKNRREIAKKLIEVGRNPKEPVAFIERGTTHEERTVISNLLEVSQSPPEVSPPAVMVVGKVVKLREILKKTIEEVLV
>NZ_CP007028.1|WP_025306167.1|907003_909262_-|CRISPR-associated-helicase/endonuclease-Cas3
MCSGLYSHPNVFMEDHINGVIKIAKQLYGENIPEWFYVPLAFHDFGKSTKYFQDYILSGKKTKFSDHSYLSAVYCLNLAHSLGFDDRLTECFLYPLKHHTDLKGLKNTFDDLLSKERRDILLKQIEAIEVEKFNRVVELLDIPERIKSKAFLGEEVLNRLKLIVGNLGRIVGGLKLEKGLFDFNLFFSVLLDADKTQAGSKEDSVPETRVLSLERIEIYREQLRKNDSEINQKREEAFKEVMAKLPIAKDYKLYALTLPTGMGKTLTGLSFAAGLAKNLGLKRIVYSLPFLSIIDQTELVLRGIGLKDSTELIVHHHLSEIGYFQGDREREYDFDTARVFFEGWNSGVILTTFHQFLYALLGAENSYLRRFNKLKDSVVIVDELQALPHRYWRFVKECFKKLTEELNSRVILMTATNPFVFEEGDHVLHLVDKAKYREGLQRFRVIPDLEKRTVEDLAREVAERVRKEDKTFLIILNTIKSSQEFYRKLKDLVNVDIAYLSTAVIPKQRRERIEQIKQGKYKVVVSTQVVEAGVDIDFDVVCRDFAPLDSINQSAGRCNRHGFRGLGEVRVVKLVDDNGREYSRRIYDIVLLSATEKFLTEELTERELLDVIDEYFETLWTKISHDKSDELLEALDRIKHDFLYKNFKLIEDQPYKEDVFVAVDYKAESVLNAVKEIWEQRQRKEISLWEAKREFEKLKAEFYSYVISVALSKDSEIELDDRLKIRVVRRENVGLYYDGEIGFRIKGGENAL
>NZ_CP007028.1|WP_025306168.1|909254_909989_-|type-I-B-CRISPR-associated-protein-Cas5
MEALVFEVFGSLGHFRKFYTTSSALTYPFPPPTVLRGLVGAIIGLEREEYLTHTKDLKFAVQILSPVKTLTISVNFINTKRKGGGFEPSLKAQSKAEESARTQVIQQLVKDPRYRVFVLGDGNVFETLREHLELRKFFYTPVLGTSEHIAEIEYVGTFEVKELEDVEGRCYSVCPLELLEDLRITSIKIGKELIPYRMEEDRTASYTEVLYPKEPNTTIEGKFKKLWFVAMPSGEVGVCFMPHV
>NZ_CP007028.1|WP_025306169.1|909988_910882_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MSILSRRHEILFLYDVSMANPNGDPLDENRPRYDEETGRVFVRDARIKRTIRDTLAEMGYNVFIIEERKDNGELKTKEEKVGNLDRDRILDTYIDIRLFGGTFAVKKNPWNWTGPVQFAYGVSLHRVKMLNIKGTTVMPSKEGKKQGTMLDDYRIAYGLIAVYGVANQNAAEHTRMTDEDFEIMLKALWIGHRGGSVLLTGSKIGHTSRLLIDVVHKEGSLDLIGGLHRAVDVVSDKNDEEIRGPEDYKLSLERLAQKILRFKDKVEKIRYIADEELRVEPSIEEAFQGITVEKLEF
>NZ_CP007028.1|WP_025306170.1|910878_912606_-|TIGR02556-family-CRISPR-associated-protein
MLRALKEWGELFERPIYDKVKADKVIVLEFELDNVGNATLKDISLEEFSEDKLNKYLYRRAKSSNPPTYSPTLRLNTEDISKSLNNLIKVNRKLRGVPQISIDVETVAERIRGMIEGTEKSTSYLITIRFNGKYIGEMPEYIKAVGDLIKGSYEKNGICSICGEEKKVAEDLPFNFLTYDKPGYIVGGFREDVAYKNSPICFDCYEKIRIARQNLESATFKLAGTEYMLIPETLKKENLQKLKELFEYLRENNLNLDNLDKVHLYDLLEGLVREEDKNLIFSILDNLQEISGERGLDILSIFSRFKDIIIAHFLFIKREQSREAIELYISDVFPSRIDYLFKVKGFIEELGIVGNFDYRLINEFFKEKGFYQMVEATFWGKRVENAFLCDGLMNVIRESFKEWDKRTDYKLIGEALAVYLFVRITTEGLSMQQSQNLQSLEEFFVWVKNLPSIGSEDWKYGLVLMGFLTEYLLEEQRKERKSKPFLKKLKSLKMDWGDIIKLLPELRQKLEEYEAFDYQSVKMLFGEISQTLLQSTKPKASVGELNFYFASGMGLYGIYGGLMFNRKQTNEEVEE
>NZ_CP007028.1|WP_169727093.1|912598_913252_-|CRISPR-associated-endoribonuclease-Cas6
MDPILASILHEVGFVYNHRKFKLFTFSKIFGKIKEKNENNILFHPPNVHVYFSTPITTHMKSIAMSLLKKERLLMHKQYVFLSEVEVLEEEIESEEITVVCLSPIVVYRTPEGSRRHIYLSPFEEQFYAMLKSNLMKKYELVYGKRYTEDIEIAPVNTNRIYKKKIVFKGTLITAWEGLFKIKAKRDMLKVGLECGLGVKNSAGFGCIAKIRKKEHA
>NZ_CP007028.1|WP_025306172.1|913846_914584_+|AAA-family-ATPase
MKTLSVVNHKGGVGKTTLTVVLLHLLAERGLKVLAVDLDPQANLTLCLTQNISEDIPQSYHLLIKGSSQPISLGNIDLIPSSLLLSQAEFELVSMHARELRLKRALSTFNSYDLILVDTPPNLGILTINALIASDGVLIPVETQFFSLSGLKHIFMVLQELEEYTGIKTQVVALAPTFYEKHVALHNKVLEELQKLPYKVLPPIPKRVGFQYASINRGDLKQLDQEALKILSTYAEEVIKWLRGT
>NZ_CP007028.1|WP_025306173.1|914565_914850_+|hypothetical-protein
MAKRNLGIVSKILSDMSATVSEEPKSEEAMKKDTLEEKKEATKNRKLKGFYLTVENEVRLKELQMMYLKKGIRVSESELVNRALEEFYFKHKKE
>NZ_CP007028.1|WP_038532144.1|915445_916189_-|hypothetical-protein
MIKLAVLQWQIAFGNIQENRKRVLELLSPLEDSLVVLPEMFPCGFDYDNLKNHAKESQKLLEELRELSKEKRLTLIGTYPEEREGKLFNTAFVLSDGLLVGKRDKIKLFPLYREGEHFSPGQENPVFETRHGKVGVLVCFELRFPNLGWELRKKGAQIIAVPSLWGAKRKEHLKVLSQARAVELQSYLLLSNGWGRTGEEEYAGNSAIYDPWGNTLAFSEVGDSVLLVYADLKKVEAVRRLIPLDTD
>NZ_CP007028.1|WP_025306176.1|916185_917088_-|MoxR-family-ATPase
MDIQGIIDSVSTVLKGKEEVVLRSLVCFLSGGHLLLEDVPGVGKTTLALSLSRVLGLSFARIQFTSDLLPSDILGVSIYDQSKKAFVFKQGPIFHQIILADEINRATPKTQSALLEAMAEGKVSVDGVTYELPKPFFVIATQNPVEQYGTFPLPESQLDRFSMRLSLGYPDKETEISILRGENPLESVAKLSPMVKPHEILATMQQISRFYVSPEVARFVVEIVSRTRNHPDVLLGVSTRGAIHLVSCAKALAYCRGRDFVVPEDIIDLAPYCLAHRIIVREGTDAEALIKSILEEVPAP
>NZ_CP007028.1|WP_025306177.1|917132_918431_-|TrpB-like-pyridoxal-phosphate-dependent-enzyme
MRVVLSTQDIPKKWFNIVPYLPKPLEPPLDPRTMEPVDPSALLAIFPEPIVEQEVSQQEWIDIPQEVLDVYSLWRPTPLHRAKRLEEYLGTPAKIYYKNESVSPPGSHKPNTAVAQAYYNKISGVKRLTTETGAGQWGSSLAFACQFFGLECEVFMVRVSYNQKPFRRILMETWGAKVVPSPSNLTQSGRKFYEEDPEHPGSLGIAISEAIERAVSSPDTKYSLGSVLNHVLLHQTIIGLEAKKQMEMVGDYPDVIVGAVGGGSNFAGLSFPFLRDKLAGEKPNLEVIAVEPSACPTLTKGEYRYDYGDTAGLTPLIKMHTLGHDFVPPPIHAGGLRYHGDAPLVCLLYNEGFISASAYKQRDVFEAAVLFARTEGIVPAPESAHAIRKVIDIALECKRTGEKKTILFNLSGHGYFDLSAYNKFLKGELPDT

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Crispr_ID: NZ_CP007028_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007028_7

913510-913678

TypeI-B

Consensus_repeat	Method
TGTTTCAATCCCCTATAGGCACTTAATAAACTAG	PILER-CR
GTTTATTAAATGCCTATAGGGGATTGAAAC	CRISPRCasFinder

2 spacers

cas6,cas8b1,cas7,cas5,cas3,TnpB_regular.1

The CRISPR arrays of NZ_CP007028_7

>merge|NZ_CP007028|7|913510-913678|PILER-CR,CRISPRCasFinder
CTGGTTTATTAGGTGCCTATAGGGGATTGAAACACTTGCTTTCTCATTGCTTAGCCTCCAGCTTATGCAAGTTTATTAAATGCCTATAGGGGATTGAAACGCCCTCTGTTCAGATGCTCCGATGCAGACTATGAACTTGTTTATTAAGTGCCTATAGGGGATTGAAACA

>NZ_CP007028|7|7|913510-913678|PILER-CR
CTGGTTTATTAGGTGCCTATAGGGGATTGAAACA	CTTGCTTTCTCATTGCTTAGCCTCCAGCTTATG
CAAGTTTATTAAATGCCTATAGGGGATTGAAACG	CCCTCTGTTCAGATGCTCCGATGCAGACTATGAA
CTTGTTTATTAAGTGCCTATAGGGGATTGAAACA

>NZ_CP007028|7|7|913513-913677|CRISPRCasFinder
GTTTATTAGGTGCCTATAGGGGATTGAAAC	ACTTGCTTTCTCATTGCTTAGCCTCCAGCTTATGCAA
GTTTATTAAATGCCTATAGGGGATTGAAAC	GCCCTCTGTTCAGATGCTCCGATGCAGACTATGAACTT
GTTTATTAAGTGCCTATAGGGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007028.1\|WP_025306172.1\|913846_914584_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379293
NZ_CP007028.1\|WP_025306122.1\|920080_921757_-\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|237783
NZ_CP007028.1\|WP_025306178.1\|918663_920031_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|376689
NZ_CP007028.1\|WP_169727092.1\|901903_902014_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|372646
NZ_CP007028.1\|WP_169727093.1\|912598_913252_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|224499
NZ_CP007028.1\|WP_038532144.1\|915445_916189_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|143607
NZ_CP007028.1\|WP_025306170.1\|910878_912606_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|378190
NZ_CP007028.1\|WP_156916201.1\|902237_903056_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_051402152.1\|903099_904755_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	TnpB_regular.1	-	gnl\|CDD\|273793
NZ_CP007028.1\|WP_025306173.1\|914565_914850_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306167.1\|907003_909262_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP007028.1\|WP_025306180.1\|922797_923298_+\|DUF29-domain-containing-protein	unknown	unknown	gnl\|CDD\|366774
NZ_CP007028.1\|WP_025306169.1\|909988_910882_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|187821
NZ_CP007028.1\|WP_025306179.1\|921897_922458_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306166.1\|904881_905913_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240017
NZ_CP007028.1\|WP_025306181.1\|923344_925177_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306168.1\|909254_909989_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP007028.1\|WP_025306176.1\|916185_917088_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP007028.1\|WP_025306177.1\|917132_918431_-\|TrpB-like-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|237087
NZ_CP007028.1\|WP_025306163.1\|901101_901605_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP007028.1\|WP_025306172.1\|913846_914584_+\|AAA-family-ATPase	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	7.63045e-53
NZ_CP007028.1\|WP_025306122.1\|920080_921757_-\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|237783	PRK14667, uvrC, excinuclease ABC subunit C; Provisional.	0
NZ_CP007028.1\|WP_025306178.1\|918663_920031_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|376689	pfam01964, ThiC_Rad_SAM, Radical SAM ThiC family. ThiC is found within the thiamine biosynthesis operon. ThiC is involved in pyrimidine biosynthesis. ThiC participates in the formation of 4-Amino-5-hydroxymethyl-2-methylpyrimidine from AIR, an intermediate in the de novo pyrimidine biosynthesis. Thic is a member of the radical SAM superfamily.	0
NZ_CP007028.1\|WP_169727092.1\|901903_902014_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|372646	pfam13610, DDE_Tnp_IS240, DDE domain. This DDE domain is found in a wide variety of transposases including those found in IS240, IS26, IS6100 and IS26.	3.30466e-05
NZ_CP007028.1\|WP_038532144.1\|915445_916189_-\|hypothetical-protein	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	2.83738e-74
NZ_CP007028.1\|WP_025306170.1\|910878_912606_-\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	9.77095e-59
NZ_CP007028.1\|WP_169727093.1\|912598_913252_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	9.68208e-34
NZ_CP007028.1\|WP_051402152.1\|903099_904755_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	1.01825e-15
NZ_CP007028.1\|WP_025306167.1\|907003_909262_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.60019e-49
NZ_CP007028.1\|WP_025306180.1\|922797_923298_+\|DUF29-domain-containing-protein	gnl\|CDD\|366774	pfam01724, DUF29, Domain of unknown function DUF29. This family consists of various hypothetical proteins from cyanobacteria, none of which are functionally described. The aligned region is approximately 120-140 amino acids long corresponding to almost the entire length of the proteins in the family. Structure 3fcn is a small protein that has a novel all-alpha fold. The N-terminal helical hairpin is likely to function as a dimerization module. This protein is a member of PFam family PF01724. The function of this protein is unknown. One protein sequence contains a fusion of this protein and a DnaB domain, suggesting a possible role in DNA helicase activity (hypothetical). Dali hits have low Z and high rmsd, suggesting probably only topological similarities (not functional relevance) (details derived from TOPSAN). The family has several highly conserved sequence motifs, including YD/ExD, DxxNVxEEIE, and CPY/F/W, as well as conserved tryptophans.	8.33978e-47
NZ_CP007028.1\|WP_025306169.1\|909988_910882_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|187821	cd09690, Cas7_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csh2 family.	8.71212e-80
NZ_CP007028.1\|WP_025306166.1\|904881_905913_+\|hypothetical-protein	gnl\|CDD\|240017	cd04659, Piwi_piwi-like_ProArk, Piwi_piwi-like_ProArk: PIWI domain, Piwi-like subfamily found in Archaea and Bacteria. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs. The central component of the RNA-induced silencing complex (RISC) and related complexes is Argonaute. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the 5' anchoring of the guide RNA and the other, the catalytic site for slicing. This domain is also found in closely related proteins, including the Piwi subfamily, where it is believed to perform a crucial role in germline cells, via a similar mechanism.	1.1064e-30
NZ_CP007028.1\|WP_025306168.1\|909254_909989_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.41491e-42
NZ_CP007028.1\|WP_025306176.1\|916185_917088_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.44628e-96
NZ_CP007028.1\|WP_025306177.1\|917132_918431_-\|TrpB-like-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|237087	PRK12391, PRK12391, TrpB-like pyridoxal phosphate-dependent enzyme.	0

>NZ_CP007028.1|WP_169727093.1|912598_913252_-|CRISPR-associated-endoribonuclease-Cas6
MDPILASILHEVGFVYNHRKFKLFTFSKIFGKIKEKNENNILFHPPNVHVYFSTPITTHMKSIAMSLLKKERLLMHKQYVFLSEVEVLEEEIESEEITVVCLSPIVVYRTPEGSRRHIYLSPFEEQFYAMLKSNLMKKYELVYGKRYTEDIEIAPVNTNRIYKKKIVFKGTLITAWEGLFKIKAKRDMLKVGLECGLGVKNSAGFGCIAKIRKKEHA
>NZ_CP007028.1|WP_025306170.1|910878_912606_-|TIGR02556-family-CRISPR-associated-protein
MLRALKEWGELFERPIYDKVKADKVIVLEFELDNVGNATLKDISLEEFSEDKLNKYLYRRAKSSNPPTYSPTLRLNTEDISKSLNNLIKVNRKLRGVPQISIDVETVAERIRGMIEGTEKSTSYLITIRFNGKYIGEMPEYIKAVGDLIKGSYEKNGICSICGEEKKVAEDLPFNFLTYDKPGYIVGGFREDVAYKNSPICFDCYEKIRIARQNLESATFKLAGTEYMLIPETLKKENLQKLKELFEYLRENNLNLDNLDKVHLYDLLEGLVREEDKNLIFSILDNLQEISGERGLDILSIFSRFKDIIIAHFLFIKREQSREAIELYISDVFPSRIDYLFKVKGFIEELGIVGNFDYRLINEFFKEKGFYQMVEATFWGKRVENAFLCDGLMNVIRESFKEWDKRTDYKLIGEALAVYLFVRITTEGLSMQQSQNLQSLEEFFVWVKNLPSIGSEDWKYGLVLMGFLTEYLLEEQRKERKSKPFLKKLKSLKMDWGDIIKLLPELRQKLEEYEAFDYQSVKMLFGEISQTLLQSTKPKASVGELNFYFASGMGLYGIYGGLMFNRKQTNEEVEE
>NZ_CP007028.1|WP_025306169.1|909988_910882_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MSILSRRHEILFLYDVSMANPNGDPLDENRPRYDEETGRVFVRDARIKRTIRDTLAEMGYNVFIIEERKDNGELKTKEEKVGNLDRDRILDTYIDIRLFGGTFAVKKNPWNWTGPVQFAYGVSLHRVKMLNIKGTTVMPSKEGKKQGTMLDDYRIAYGLIAVYGVANQNAAEHTRMTDEDFEIMLKALWIGHRGGSVLLTGSKIGHTSRLLIDVVHKEGSLDLIGGLHRAVDVVSDKNDEEIRGPEDYKLSLERLAQKILRFKDKVEKIRYIADEELRVEPSIEEAFQGITVEKLEF
>NZ_CP007028.1|WP_025306168.1|909254_909989_-|type-I-B-CRISPR-associated-protein-Cas5
MEALVFEVFGSLGHFRKFYTTSSALTYPFPPPTVLRGLVGAIIGLEREEYLTHTKDLKFAVQILSPVKTLTISVNFINTKRKGGGFEPSLKAQSKAEESARTQVIQQLVKDPRYRVFVLGDGNVFETLREHLELRKFFYTPVLGTSEHIAEIEYVGTFEVKELEDVEGRCYSVCPLELLEDLRITSIKIGKELIPYRMEEDRTASYTEVLYPKEPNTTIEGKFKKLWFVAMPSGEVGVCFMPHV
>NZ_CP007028.1|WP_025306167.1|907003_909262_-|CRISPR-associated-helicase/endonuclease-Cas3
MCSGLYSHPNVFMEDHINGVIKIAKQLYGENIPEWFYVPLAFHDFGKSTKYFQDYILSGKKTKFSDHSYLSAVYCLNLAHSLGFDDRLTECFLYPLKHHTDLKGLKNTFDDLLSKERRDILLKQIEAIEVEKFNRVVELLDIPERIKSKAFLGEEVLNRLKLIVGNLGRIVGGLKLEKGLFDFNLFFSVLLDADKTQAGSKEDSVPETRVLSLERIEIYREQLRKNDSEINQKREEAFKEVMAKLPIAKDYKLYALTLPTGMGKTLTGLSFAAGLAKNLGLKRIVYSLPFLSIIDQTELVLRGIGLKDSTELIVHHHLSEIGYFQGDREREYDFDTARVFFEGWNSGVILTTFHQFLYALLGAENSYLRRFNKLKDSVVIVDELQALPHRYWRFVKECFKKLTEELNSRVILMTATNPFVFEEGDHVLHLVDKAKYREGLQRFRVIPDLEKRTVEDLAREVAERVRKEDKTFLIILNTIKSSQEFYRKLKDLVNVDIAYLSTAVIPKQRRERIEQIKQGKYKVVVSTQVVEAGVDIDFDVVCRDFAPLDSINQSAGRCNRHGFRGLGEVRVVKLVDDNGREYSRRIYDIVLLSATEKFLTEELTERELLDVIDEYFETLWTKISHDKSDELLEALDRIKHDFLYKNFKLIEDQPYKEDVFVAVDYKAESVLNAVKEIWEQRQRKEISLWEAKREFEKLKAEFYSYVISVALSKDSEIELDDRLKIRVVRRENVGLYYDGEIGFRIKGGENAL
>NZ_CP007028.1|WP_025306166.1|904881_905913_+|hypothetical-protein
MRDLENRARIIENTVLKRVSSLGLYIDRLKPIPIPIPTDVKEFSLLPHVGDLEGSNTFLFVLTDASKLDDELYLDIKRDLLEFDIQSQVIYYRTNVGDRYVACNLMLGLLGKTGNYPYFLKDSSNKVFVGIDLSRKARSSNKGIVHAVGTAIIVDTSDGGTITYKNINVPAGGEAVEKAYVKSLANMLYKYKDKFIVIHRDGRMGVDELNAYVEVFSKQFGRENFALVSIIKSGTPRILQINSNIVGNPPKGCAILLSEREAVISTYEVKESFGTHIPLRIKVLYGDYPLNEAIEDVLRLTLLNFSSFTLNKLPATVAFADRIAWYNLHGIGPEDTDGNLFFL
>NZ_CP007028.1|WP_051402152.1|903099_904755_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MVLSIAGSKNFSEEKAHKLYITLECMLEFEKEEEKEKVLALMRRFSSATRYAYKRLLEGVAEKEIEKATQEKHKLNARYVKDAVLIAKQVLKSCMQRGQNPKKLVFGSRELFEKLKKKHLTGKRREKLRQRWEERRYCYLYSRGEKFHKGNLNLRFVNLNNQWHLRINLGNGEYVWAKVVRNAKRHKDKWIDFTWRLLEAEKSGEWFAYNVRLKVRNGKFYAQVSWEEKTVEPVITKAYGVIGIDINAYPFHLALAYVSTDGNLEKFERIDLREMEGKTKNQREHIAWHIARQVVERALENGKAIVVEDLQKVPKGRRGDGLAKLRRKLHKWAYRSVLEKIEVYARSMGVQLIKVNPAYTSIIGKLKYSPMLGIDKDVAGAYVIGRRGLGFEERLPKNYRELLKDKEFLAYAIAKVDERINKLKSELKRETNEYKRNALKERVKRLRKYLELLLSYTRDSGKSEPATQQAVNREMKPMRGRAKSLQKSWRVLSVALAVLLATTCLEWCRDHSPLKRVLISGDWARVAGKGSPSLPGQGTTAQNKCSFIHFG
>NZ_CP007028.1|WP_156916201.1|902237_903056_+|hypothetical-protein
MLYTYKEYEKPFFYDRETIISLVDIGDSFEDDYYVLEKESSNPEYFFSSPQAWSTFINSFANLLMIYKKDTVRISKGIARKYILGTEFIDQRAYLRIDFKYMLFFPETLYRQLERGEQPEIGGKYYTPSRSVATLKEYRKVSVEEYEKLMKEMLPRSSEITKDRWEKGLEKAKQRGYGYIAIVVFDEVDEDDGREYTYPANALVKVRYIEDLDREELQRIRPKSKERWELIERFRDRVASLLREHSIGLDEEPYTKIEYIAPSFEVVDGGGG
>NZ_CP007028.1|WP_169727092.1|901903_902014_+|DDE-type-integrase/transposase/recombinase
MDKTKIKARDRTYYLWLAVDERGLPVSVHLSRRRDS
>NZ_CP007028.1|WP_025306163.1|901101_901605_-|hypothetical-protein
MPKVDIFSEIETFSSCLKFFPQKVESIQIERLGKEKGYISPLWDLAWHDLYLLQLFFESIRIEKLTVNKVWEPHGRADDVPFYIRTAWQYPQPTRRWIMNSGQVILDFAREEVWGENKLIHMEEKRDKLRLMSESFIKGGFDQKSKERAKKNLILLEHIERLPATSF
>NZ_CP007028.1|WP_025306172.1|913846_914584_+|AAA-family-ATPase
MKTLSVVNHKGGVGKTTLTVVLLHLLAERGLKVLAVDLDPQANLTLCLTQNISEDIPQSYHLLIKGSSQPISLGNIDLIPSSLLLSQAEFELVSMHARELRLKRALSTFNSYDLILVDTPPNLGILTINALIASDGVLIPVETQFFSLSGLKHIFMVLQELEEYTGIKTQVVALAPTFYEKHVALHNKVLEELQKLPYKVLPPIPKRVGFQYASINRGDLKQLDQEALKILSTYAEEVIKWLRGT
>NZ_CP007028.1|WP_025306173.1|914565_914850_+|hypothetical-protein
MAKRNLGIVSKILSDMSATVSEEPKSEEAMKKDTLEEKKEATKNRKLKGFYLTVENEVRLKELQMMYLKKGIRVSESELVNRALEEFYFKHKKE
>NZ_CP007028.1|WP_038532144.1|915445_916189_-|hypothetical-protein
MIKLAVLQWQIAFGNIQENRKRVLELLSPLEDSLVVLPEMFPCGFDYDNLKNHAKESQKLLEELRELSKEKRLTLIGTYPEEREGKLFNTAFVLSDGLLVGKRDKIKLFPLYREGEHFSPGQENPVFETRHGKVGVLVCFELRFPNLGWELRKKGAQIIAVPSLWGAKRKEHLKVLSQARAVELQSYLLLSNGWGRTGEEEYAGNSAIYDPWGNTLAFSEVGDSVLLVYADLKKVEAVRRLIPLDTD
>NZ_CP007028.1|WP_025306176.1|916185_917088_-|MoxR-family-ATPase
MDIQGIIDSVSTVLKGKEEVVLRSLVCFLSGGHLLLEDVPGVGKTTLALSLSRVLGLSFARIQFTSDLLPSDILGVSIYDQSKKAFVFKQGPIFHQIILADEINRATPKTQSALLEAMAEGKVSVDGVTYELPKPFFVIATQNPVEQYGTFPLPESQLDRFSMRLSLGYPDKETEISILRGENPLESVAKLSPMVKPHEILATMQQISRFYVSPEVARFVVEIVSRTRNHPDVLLGVSTRGAIHLVSCAKALAYCRGRDFVVPEDIIDLAPYCLAHRIIVREGTDAEALIKSILEEVPAP
>NZ_CP007028.1|WP_025306177.1|917132_918431_-|TrpB-like-pyridoxal-phosphate-dependent-enzyme
MRVVLSTQDIPKKWFNIVPYLPKPLEPPLDPRTMEPVDPSALLAIFPEPIVEQEVSQQEWIDIPQEVLDVYSLWRPTPLHRAKRLEEYLGTPAKIYYKNESVSPPGSHKPNTAVAQAYYNKISGVKRLTTETGAGQWGSSLAFACQFFGLECEVFMVRVSYNQKPFRRILMETWGAKVVPSPSNLTQSGRKFYEEDPEHPGSLGIAISEAIERAVSSPDTKYSLGSVLNHVLLHQTIIGLEAKKQMEMVGDYPDVIVGAVGGGSNFAGLSFPFLRDKLAGEKPNLEVIAVEPSACPTLTKGEYRYDYGDTAGLTPLIKMHTLGHDFVPPPIHAGGLRYHGDAPLVCLLYNEGFISASAYKQRDVFEAAVLFARTEGIVPAPESAHAIRKVIDIALECKRTGEKKTILFNLSGHGYFDLSAYNKFLKGELPDT
>NZ_CP007028.1|WP_025306178.1|918663_920031_+|phosphomethylpyrimidine-synthase-ThiC
MLSAEWVESRKKFKNKTQMHLARQGIITEEMRYVAKREGLHPEFVRQEVARGRMIIPANINHLHLEPMCIGINSRVKVNANIGNSGLASDIPTELEKLRVAIKYGADTVMDLSTGDAIKETREAIIKESTVPVGTVPIYEAFKRAKGQVKNMTVDLILDVIEEQAQQGVSYMTIHAGILREFLPMVQHRVMGIVSRGGAIMAQWMIEHGKQNPLYEHFDKICEIFKKYDVSFSLGDALRPGAIADASDDAQLAELRVLGELTERAWKHDVQVMVEGPGHVPLDQIEFNMKIQQKICHEAPFYVLGPLVIDVAPGYDHIASAIGAALAGYYGAAMLCYVTPKEHLGLPNVEDVKQGVIAYKIAAHAADVAKRFPGARDWDLEMSKARFAFDWNRQFELAIDPETARAYHDETLPQEGYKTAKFCSMCGPEFCAYKISQHVSDKMEELLQQENWIAP
>NZ_CP007028.1|WP_025306122.1|920080_921757_-|excinuclease-ABC-subunit-UvrC
MLELIKSAPTQCGVYLFKKGNKVLYVGKAKNIRERLLQHYKQAQENKKEYAIVNSSDRIDWILTRNEYEALVLEVDLIQLHKPKYNVLHKHGGGYPVLLLTEDEFPTIKVVRGSEHEGKLFGPFFTAKRAYRVKRLIHKLFKLRTCDPMPTRASPCMDYHLGLCSGPCAGLISKEDYSLAVKSAQSMLSGEVSEVLPELYQRMEEHMERLEFEKCALIRDQIRALEKLSLGQSVSGLPYQRADLFYRIGRLLGVFLIRSFKLVDKEVFLLETEEELEETIIGFYYSNPLPEVLLLNFELSEEVKRWLSERGKVEIVQKIDQSLEELVKENLHHYMPPELWQEEFLKVLKIPPPRIIEGFDVSHFYGGYTVASCVVWEEGTMNKKRYRRYRIKTVNQIDDYASLEEVLSRRARRLKEGEETMPDLWLIDGGLGQLSVAIRVRDRFGLPIKVVSLAKEEEILLTEWGQRVRLKEHPILYRIFGQIRDEAHRFALSYNRKLRLKEGLKDILDRIKGIGEVKKKIIYNNFENLYELLKAEDRHLKKLGIDPSIKQEIEKYLT
>NZ_CP007028.1|WP_025306179.1|921897_922458_-|hypothetical-protein
MAKDDWRIKGGRRKGKKALKYAGLLWGDEKERRITLEDLCRCWNLGRLLKEGELQLGMLVFSQKQRYKLSHSQQMTLYYAYLVFKDWANKTQKHINGKALSKLIQYLMATTLVQNAKFCTCKEIFSFFTYDLPKLKDREGKKPRPLELYQRQSDPQALAKIHKTLSFLQNPEKVLKLGKLFGIPLR
>NZ_CP007028.1|WP_025306180.1|922797_923298_+|DUF29-domain-containing-protein
MEKTTQSIKELYEKDFYLWVQENLRLLRNKEYDLVDWENLLEEIEDMARRELRSLISFMAVILEHLYKWENFRDREDVGHSWIKSINNARNELDTILETYPGIRKKAAEELPTAWRIAVKRLVRWFKEDENHDLAKKYFGKFPTEKDFPQECPYTFEQVMEYEPWV
>NZ_CP007028.1|WP_025306181.1|923344_925177_+|hypothetical-protein
MIASLGGYAFHSFATGLGGVVQGTAQSSAGDVARGSFNAGQVNYRNVSAGTTSLGSFVGWRTDFFTTSGLQHTVGNITMQGGRVEGKGLSVDNALKLAAIRGDDFTQKVIASMSAIAGQGASASMVINPQGRLEHAEMVSGDGGFKVVYDGRGRLVVMKGGVEHGSIELDEKGEIKGFETSVQVGGLSLDYVKTKAKEITETARAYSQVGEAFKTIASKGIEAVDLKSLRDNLSKIVQSDFASFLEAAKAWGVDKDIVQAILKTLGQKYGSEFKTRDSFGFEFNLSGGVGVGTGGGNKQGGSFWPLQFGGGASGGLNWNYTDEQVKAMSTYLSRDEKNELVNKFIESLQNKSGQRSSDSQTKKSEQSYTQGKDVSEKASNSKVYEVAEAFGKQAEEMLAYAERLQASLKQDPLNYYAQQKYKEALAAGKSKGEAVRYAMEEVAKLRSNPEALEKWLEEFAKGQGIRDPKVDEKRLEGIQSEVPDPKNVQEKGKQLQGEVNQQINKTQEEMSQRKKELESYKPPKAKLFNLQAPDIDLRFNLNDPKLRAYEKDAQKWFKEQPSIPVRIFNDGKAAVNWEIDLGKNLAKNLINAPNPKVGDRLNTPPLQGVP

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Crispr_ID: NZ_CP007028_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007028_8

1340669-1340766

Orphan

Consensus_repeat	Method
GGAGGAGTCGAACCTCCGACCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007028_8

>merge|NZ_CP007028|8|1340669-1340766|CRISPRCasFinder
GGAGGAGTCGAACCTCCGACCTCCATCGTGTGAGGATGGCGCTCTACCACTGAGCTAATCGCCCATCCGTCCCCGGGAGGAGTCGAACCTCCGACCTC

>NZ_CP007028|8|8|1340669-1340766|CRISPRCasFinder
GGAGGAGTCGAACCTCCGACCTC	CATCGTGTGAGGATGGCGCTCTACCACTGAGCTAATCGCCCATCCGTCCCCG
GGAGGAGTCGAACCTCCGACCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007028.1\|WP_025306604.1\|1336743_1337469_+\|LPS-export-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213185
NZ_CP007028.1\|WP_025306614.1\|1344602_1345085_+\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|223741
NZ_CP007028.1\|WP_025306606.1\|1339038_1339782_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|349953
NZ_CP007028.1\|WP_025306605.1\|1337431_1339042_-\|type-I-DNA-topoisomerase	unknown	unknown	gnl\|CDD\|223624
NZ_CP007028.1\|WP_025306600.1\|1332739_1333822_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_CP007028.1\|WP_025306607.1\|1339778_1340645_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|274043
NZ_CP007028.1\|WP_025306608.1\|1340821_1341307_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306610.1\|1342093_1342819_-\|pyridoxine-5'-phosphate-synthase	unknown	unknown	gnl\|CDD\|235380
NZ_CP007028.1\|WP_025306617.1\|1346039_1346840_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|223890
NZ_CP007028.1\|WP_025306611.1\|1342821_1343637_-\|thiazole-biosynthesis-adenylyltransferase-ThiF	unknown	unknown	gnl\|CDD\|236337
NZ_CP007028.1\|WP_025306599.1\|1331033_1332740_+\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|273815
NZ_CP007028.1\|WP_025306603.1\|1336163_1336619_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306616.1\|1345651_1346056_+\|septal-ring-lytic-transglycosylase-RlpA-family-protein	unknown	unknown	gnl\|CDD\|223868
NZ_CP007028.1\|WP_025306612.1\|1343659_1344055_-\|S-adenosylmethionine-decarboxylase	unknown	unknown	gnl\|CDD\|234926
NZ_CP007028.1\|WP_025306598.1\|1330781_1331021_+\|sulfurtransferase-TusB	unknown	unknown	gnl\|CDD\|274388
NZ_CP007028.1\|WP_025306601.1\|1333811_1335233_-\|4-alpha-glucanotransferase	unknown	unknown	gnl\|CDD\|237738
NZ_CP007028.1\|WP_025306609.1\|1341299_1342094_-\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|334588
NZ_CP007028.1\|WP_051402179.1\|1335376_1336120_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306613.1\|1344151_1344610_+\|RsmD-family-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223813
NZ_CP007028.1\|WP_025306615.1\|1345081_1345522_-\|glycine-cleavage-system-protein-H	unknown	unknown	gnl\|CDD\|237370

Protein	Function_ID	Function_description	E-value
NZ_CP007028.1\|WP_025306604.1\|1336743_1337469_+\|LPS-export-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213185	cd03218, ABC_YhbG, ATP-binding cassette component of YhbG transport system. The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.	5.98819e-117
NZ_CP007028.1\|WP_025306615.1\|1345081_1345522_-\|glycine-cleavage-system-protein-H	gnl\|CDD\|237370	PRK13380, PRK13380, glycine cleavage system protein H; Provisional.	1.00558e-78
NZ_CP007028.1\|WP_025306606.1\|1339038_1339782_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|349953	cd18080, TrmD-like, tRNA-M1G37-methyltransferase TrmD. The bacterial tRNA-(N(1)G37) methyltransferase (TrmD) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the N1 position of G37 in the anticodon loop of a subset of tRNA that contains a G at position 36. The presence of the modification prevents Watson-Crick base-pairing of this guanosine with cytosine in mRNA and translational frame-shifting. This family of proteins contains members of the SPOUT methyltransferases. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	1.20361e-110
NZ_CP007028.1\|WP_025306605.1\|1337431_1339042_-\|type-I-DNA-topoisomerase	gnl\|CDD\|223624	COG0550, TopA, Topoisomerase IA [DNA replication, recombination, and repair].	0
NZ_CP007028.1\|WP_025306600.1\|1332739_1333822_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	2.24086e-159
NZ_CP007028.1\|WP_025306607.1\|1339778_1340645_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|274043	TIGR02225, Tyrosine_recombinase_XerD, tyrosine recombinase XerD. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerD, one of two closely related chromosomal proteins along with XerC (TIGR02224). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and with homologs of XerD on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerD, as some apparent XerD examples score below the trusted and noise cutoff scores. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	6.42444e-22
NZ_CP007028.1\|WP_025306614.1\|1344602_1345085_+\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|223741	COG0669, CoaD, Phosphopantetheine adenylyltransferase [Coenzyme metabolism].	1.48175e-75
NZ_CP007028.1\|WP_025306610.1\|1342093_1342819_-\|pyridoxine-5'-phosphate-synthase	gnl\|CDD\|235380	PRK05265, PRK05265, pyridoxine 5'-phosphate synthase; Provisional.	5.59024e-135
NZ_CP007028.1\|WP_025306617.1\|1346039_1346840_-\|radical-SAM-protein	gnl\|CDD\|223890	COG0820, COG0820, Predicted Fe-S-cluster redox enzyme [General function prediction only].	3.07809e-58
NZ_CP007028.1\|WP_025306601.1\|1333811_1335233_-\|4-alpha-glucanotransferase	gnl\|CDD\|237738	PRK14508, PRK14508, 4-alpha-glucanotransferase; Provisional.	0
NZ_CP007028.1\|WP_025306599.1\|1331033_1332740_+\|FAD-binding-protein	gnl\|CDD\|273815	TIGR01812, Fumarate_reductase_flavoprotein_subunit, succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative/mitochondrial subgroup. This model represents the succinate dehydrogenase flavoprotein subunit as found in Gram-negative bacteria, mitochondria, and some Archaea. Mitochondrial forms interact with ubiquinone and are designated EC 1.3.5.1, but can be degraded to 1.3.99.1. Some isozymes in E. coli and other species run primarily in the opposite direction and are designated fumarate reductase. [Energy metabolism, Aerobic, Energy metabolism, Anaerobic, Energy metabolism, TCA cycle].	0
NZ_CP007028.1\|WP_025306616.1\|1345651_1346056_+\|septal-ring-lytic-transglycosylase-RlpA-family-protein	gnl\|CDD\|223868	COG0797, RlpA, Lipoproteins [Cell envelope biogenesis, outer membrane].	1.52374e-48
NZ_CP007028.1\|WP_025306612.1\|1343659_1344055_-\|S-adenosylmethionine-decarboxylase	gnl\|CDD\|234926	PRK01236, PRK01236, S-adenosylmethionine decarboxylase proenzyme; Provisional.	1.91163e-78
NZ_CP007028.1\|WP_025306598.1\|1330781_1331021_+\|sulfurtransferase-TusB	gnl\|CDD\|274388	TIGR03011, sulf_tusB_dsrH, sulfur relay protein TusB/DsrH. The three proteins TusB, TusC, and TusD form a heterohexamer responsible for a sulfur relay reaction. In large numbers of proteobacterial species, this complex acts on a Cys-derived persulfide moiety, delivered by the cysteine desulfurase IscS to TusA, then to TusBCD. The activated sulfur group is then transferred to TusE (DsrC), then by MnmA (TrmU) for modification of an anticodon nucleotide in tRNAs for Glu, Lys, and Gln. The sulfur relay complex TusBCD is also found, under the designation DsrEFH, in phototrophic and chemotrophic sulfur bacteria, such as Chromatium vinosum. In these organisms, it seems the primary purpose is related to sulfur flux, such as oxidation from sulfide to molecular sulfur to sulfate. [Protein synthesis, tRNA and rRNA base modification].	2.89715e-08
NZ_CP007028.1\|WP_025306611.1\|1342821_1343637_-\|thiazole-biosynthesis-adenylyltransferase-ThiF	gnl\|CDD\|236337	PRK08762, PRK08762, molybdopterin-synthase adenylyltransferase MoeB.	1.5472e-158
NZ_CP007028.1\|WP_025306609.1\|1341299_1342094_-\|site-specific-DNA-methyltransferase	gnl\|CDD\|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	2.28428e-12
NZ_CP007028.1\|WP_025306613.1\|1344151_1344610_+\|RsmD-family-RNA-methyltransferase	gnl\|CDD\|223813	COG0742, COG0742, N6-adenine-specific methylase [DNA replication, recombination, and repair].	1.01832e-33

>NZ_CP007028.1|WP_025306607.1|1339778_1340645_-|tyrosine-type-recombinase/integrase
MELLELWRRHLEKTKSERTTITYLNAINSFLRKLQLPSHKLVEVSSADLYQYADSSELSPASLLTHFSALRHFYRFLARRGYIEKEKYSEIEETIEDIKEDYGLKVIHRKPKALSKSELEKIFQKVKGSKYENVYKLFLYSGVRLSEYKNLSSDHFFLDKSGIYWLHLPAEITKRKKERIAPLIGPTKEETFRFTQELSRWLEDYDANLRVKAGSLQVYTNRLSKRLGIDFSLHSFRHTYITNLINQGFPAELVKEFAGHANVKTTIDIYYRFNQERAKALVDEFLKR
>NZ_CP007028.1|WP_025306606.1|1339038_1339782_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKFFFLTIFPDLVKCFCEHGIVSQAIKKGALEVVVINLRDYAEKGKVDDYAYGGHPGMVLKPEPIFLAYEDLVSKYGKPYVIIPQPWGKVIDQRDLDRLSKLDSLLVICGRYEGIDERVSTLADEELSLGDFVLSGGELFGLVLLEGIARLLPGVLSDPQSIERDSFRRWLGSPVYTRPAEFRGMKVPEVLLSGNHKMIELWELWHSIKRTLEKRPDLIPKDLTPLEEEMLRAIKENLSFEEWVQKR
>NZ_CP007028.1|WP_025306605.1|1337431_1339042_-|type-I-DNA-topoisomerase
MILFLVESFTKAKTISKYLGKDYLVKATGGHIKDLPEDRLGVDLETLNPTFLWRKGKKKLFDEIKKSSLKAQLVLLGTDPDREGEAISYFLWEELKRVVNIPIRRVYFYEITKPALQKAIKEQTNINMNLVKAQFARRVLDRLIGYLLSPELQKSLKTRGLSVGRVQSPALRLIVEREREIQSFKKKKFYYIRALFEGFSAYLGVRFEKPDNAKPYLEKLKDVFFEVKEVQEWEEMVPPPKPFNTPELQKTANERLDFSVEKTTRLAQLLYEEGYITYPRTDAHRMSPEKATEFLQWIEKNYGVEYVGRLRKFREKAHVQSAHECIRPTSLVKKPPPGDSLELFELIVGRTLASLSTPAVLKNTKVMLTPLTQGIPFEFIAKGRTLVFDGWTRFEDYDFMEEKLPKLEKGQILKPQKIILEERQTEPPKRYTEGSLVKKLESLGIGRPSTYATIIKTLKERGYVVVEKGYLKPTETSFLVLDYLMENFPKLVDYQYTAKMEEVLDLVEEGKKDWKSAVRELFKEITDGNPYPNKLP
>NZ_CP007028.1|WP_025306604.1|1336743_1337469_+|LPS-export-ABC-transporter-ATP-binding-protein
MEKRLSAYGLRKSFKGREVLKGIDLYIERGEVVGLLGPNGAGKTTLFNCLVGFLSVDDGTIELEGKDITHLPTHKRAKEGISFLPQEHTLFEDLTVIENLLIFLEFFEESKESALARAEELLSDFGLYELRNQKAGNLSGGQKRRLEIARALIPKPKYLFFDEPFAGIDPIMVADIKELILNLKAQDIGVLITDHNVRETIRLVDRVYIISEGTVIAQGPPKDVILNQRVREVYLGKDFHL
>NZ_CP007028.1|WP_025306603.1|1336163_1336619_-|hypothetical-protein
MFGANRIVDIPEDAIMNINYVVLKEGVTLDDVAEKVAYLCEHVKTYHSDTGFYGGFVALNTGGVSLEGSTAGQVTEHPLKEREVLIITFWRSLEDHEESHRSERFNQLFKELTELAESTFEVVYQVLWQGKAYDPEMAKKAKEVKETYAEK
>NZ_CP007028.1|WP_051402179.1|1335376_1336120_+|hypothetical-protein
MPTHREKIERAIREALASSQEGLRYSELVRYIKEKHPEIKENTIHGALHNLREKIRRGDIKNIAIPERGLFRLVREEAPPKPVEEIREQDLYQPFAQYLTDELEECSKAVPLGGKVFEDKWGTPDVFGIYRFPDYEPIKLPVPEIVSAEIKLDPNQLVVAFGQACAYKLFSHKVYLVVPKGSEEIGRLESLCLRFGLGLILFEIEGKEPRFYIRTRAVKSEPDYMYLNEYLNKLKQRRPNIFKELFG
>NZ_CP007028.1|WP_025306601.1|1333811_1335233_-|4-alpha-glucanotransferase
MHRWAGVLLHISSLPSPFCVGDLGRSAYLFVDFLSNSGQGLWQVLPLNPTFEEFGNSPYFSTSLFAGNPLFVSPEILEEEGLISKETLDKVKEKPTQRVDYSKAYFVKDLILEEAFRNFSEDRDFWQFEEENVHWLEDYAVFSALKKKNRSSWDRWTELKPDPLDVKREKFRQYVFYRQWFRLKSYANEKGVRIIGDIPIYPAFDSADVWKNQRLFRLDVCAGVPPDYFSPEGQLWGNPVYNWQALREENFEWLVKRIEHSLKLYDLLRIDHFRGFVSYYVVPKGRQNAKEGWWERAYPEEFFSLLKDRFPEFPFIAEDLGTIDREVEELRDRFGFVSTRVLAFAFFEPNSTHLPHNHNQNCAVYTTTHDNMPLKDWFVEELNPAHRERLEKYLGKSLDRENVSKELIRLAYMSVAKYCVIPMQDLLNLGKESRMNTPGTAKGNWEWRMDQLPPAELSLWLLELSEIYQRLNT
>NZ_CP007028.1|WP_025306600.1|1332739_1333822_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MRVGILGGGQLGWMTILEGRKLGFEFFVADDMPHSPARKVADLCFDYSEIDEFVKLCDVITYEFEHIPEEILEKTAPLTFPSVEILKLKKSKVEEKLFLKKRGYPVPTFTVAFKEDLEQKVGLLNLPVVVKAEALGYDGKGQYLIKSLQDLQKVKANHGEKERFLVEEFVDFDFELSIIGVRSLRGEVRLYPPTINYHREGILFYNHTTSMVFPEGEEIVRSLMEELNLVGVLCVEFFYTKKGKLLINEMAPRVHNTGHHTLDSAYTSQFENLLRAITGLPLGSTKLKSHAGMLNLLGVSYEEIDWKKVLSVEGTKLYWYGKEKKHRRKMGHINLVASTEEEVVEKLNQLYDMIYEPIKC
>NZ_CP007028.1|WP_025306599.1|1331033_1332740_+|FAD-binding-protein
MNYYDVVVVGAGGAGLRAAIEASLDPTIRVAVVSKVYPTRSHTGAAQGGINAALGNVIPDDSPDSHAFDTIKGSDFLADQEAVFFMCENAPEIIYELDRWGVPFSRLPDGRIAQRPFGGASFPRTVFSADRTGHVILHTLFEQALARENIHFYNEYFLLDIIHDGNRVKGVALYDIKNGEVVNLRAKAVILATGGFARIYWKRSTNAIGNTGDGVAAALRAGLSLKDMEFIQFHPTGLAKTGILLSEACRGEGGYLLNALGERFMQRYAPEKMELAPRDMVSRAIEYEIREGRGVGEGTSAYVYLDLRHLGEEKIKERLPQVRQLAIDFEGVDPVKDLVPIRPTAHYCMGGIHVVNYRTSGTELEGLYAVGECACVSVHGANRLGGNSLTEILVFGKFCGIAAREYAKQVDWLPLTEGEERRAQEFIEGLMKREGTEKLAEVRKRMGDITWEKVGIFRDEKSLKSAYEELGELLERWERIPVVDKSKVFNTNLVELLELRNMLELARVVAFSALHRKESRGGHMREDYPNRDDKNFLKHTLVRKVGDRLELEYIPVNIVKYEPAQRSY
>NZ_CP007028.1|WP_025306598.1|1330781_1331021_+|sulfurtransferase-TusB
MVKTLWLVRKLGDFSSDLVGEDDIVVLIQDAVLRFPYKRNWYACKEDVEARGLKVSPDKLKSYEDIAELILTAQKVVVW
>NZ_CP007028.1|WP_025306608.1|1340821_1341307_-|hypothetical-protein
MFDPSKVRKERTEWRDLELSKRHREWGFHCPAVDIDFLMVEYYYGKPVAIIDYKRFTGSKNNTHPKSYEAISILADNSHIPFFVVYYYDNPWSFRLEPINNIAKKIFEKNKKRLNKCLTEREYVEFLYWLRGHKLSQEEKRILEGLNNTLPKHCKGNRDVL
>NZ_CP007028.1|WP_025306609.1|1341299_1342094_-|site-specific-DNA-methyltransferase
MKRGVLKHDPELFRNELLAYKGSYFDFFMEKGKSLSKLEKRKLREWLKSQRPPQPPFLELYHKDVRDYKDILLPESVDWVITDPPYSKKFLWVYEVLGELSAYVLKPGGGLLVMVGQSYLPEIIGKLSSKLNYVWTLAYLTPGGQSPYLWRIRCNSFWKPVLLFSKGKYSGDSFGDVVKTSPNNNDKRFHRWGQSEEGFELLFDKFVFPGQTILDPFVGGGTTAVVALKRGCNFIGIDNDLSALLTTKKRCQALGLDFILKGHV
>NZ_CP007028.1|WP_025306610.1|1342093_1342819_-|pyridoxine-5'-phosphate-synthase
MRLGVNIDHVATLRQARRTFEPSPVFCALLAEQAGAHQITLHLREDRRHIQEEDLRLIKKLVRVPVNLEMAPTEEMKRIALEVKPNRVTLVPERREEITTEGGLDVARLKDYLKEFLREIKEEGIEVSLFVEPEEEQIYASKEVGADAVELHTGRYANLWNAHNWKGVEEELQRLKTAAIKARDLGLRVYAGHGLTYQNVKDLVKELKDYVEELNVGHSIVSNAVVFGFERAVREFLMIIQ
>NZ_CP007028.1|WP_025306611.1|1342821_1343637_-|thiazole-biosynthesis-adenylyltransferase-ThiF
MFKFTEEQIKRYARHIILPEVGGKGQEKLLNSKVLVIGAGGLGSPAILYLAAAGVGTIGIVDFDVVDLSNLQRQIIHNTERVGTPKVESARRTVEMLNPDVKVITYNTRISKENIMDIIKDYDVVLDGTDNFPTRFLINDACYFAGKPLVSAAMLRFEGQVSVFDFRMKEQSPCYRCLFPEPPPPGLVPSCQEAGILGSIGGIMGCIQATEAIKLILGIGEPLVGKLLIMDALSMDFRKVKLRKDPNCPLCGEKPVIKELIEYEQVCDVHF
>NZ_CP007028.1|WP_025306612.1|1343659_1344055_-|S-adenosylmethionine-decarboxylase
MAKALGLHILADLHGVNPDLIDRVEDIKNLLETAVRVAGLTKISSHYYQFQPHGATGVILLAESHISIHTWPEHGLATVDVYTCGDPSKAYKAMDYIISTLEPSRVDKQVHERGLVGSSEGQELRSILLNI
>NZ_CP007028.1|WP_025306613.1|1344151_1344610_+|RsmD-family-RNA-methyltransferase
MKKSSRKKLLRPTSSMVKQAVFNMLGDIEGMLFIDLFAGTGQMGFMAMERGAEVIFVEKNRKFAQAIKEKGGKVIISDAIKFLEHLEDKPDIIFADPPYDYENYQKLIELALEKLNNGGFFILEHRKGQNFGAEKVKTYGDTALSIWRKEDD
>NZ_CP007028.1|WP_025306614.1|1344602_1345085_+|pantetheine-phosphate-adenylyltransferase
MISVVYPGTFDPPHLGHLDIVKRSCELFDRVVVAIAKSPRKYLLFNLEERVDMFRVMVEPLGSKVEVKGFDGLLVDFMRKEGLRVIVRGVRLFTDFEYELQIALNNSKLAGVETIFMMPSQEYIHISSTIVRDIASYCGTLEGLVHPYVAKKLREKFHCP
>NZ_CP007028.1|WP_025306615.1|1345081_1345522_-|glycine-cleavage-system-protein-H
METYKGCKIPKELYYDIENQVWYRLEEDGTVTVGATDVGQTRAGRMVNVRIKPPGKHVPKGKPIASLESGKWTGPIPAVIEGEIVERNEKLFDQPDLINDDPYGEGWIARLKPTNLERDLKDLVTGDVALQKMKEYIEREGVECKG
>NZ_CP007028.1|WP_025306616.1|1345651_1346056_+|septal-ring-lytic-transglycosylase-RlpA-family-protein
MKRWFFVLCLAFGFSYAQECKVLEGYASWYGEKFHGRKASSGERFDKFKYTAASKYFDMHTYLLVRNLENGREVVVRVNDKGPHKKGRIIDLSKSAAEKLGMLKKGVAKVQVMPLHCVAKDDQEEVIVDLIKTD
>NZ_CP007028.1|WP_025306617.1|1346039_1346840_-|radical-SAM-protein
MKLLLELQSELNRLFLFELKDGSRIESVFYRGDTLCISTQVGCALGCPFCLSGSKGLLRNLSAEEIYSQYKLLKDRLPIKRIAMSGIGEPLMNYANVQEAFWMLKEEGLKVSFYTTGFPTEKLPMLLSLPHNGVTISVHTVREEKRKLLIPHGGSLEKLISTLKHSLKELSSSRRKKIALAYLLMKGINDTEEELLEFSRLVKELGLRAVLLYYNSTKPDFEAPSPEEYERAFLTLKAQGIKVTLSTRYRKDKLGGCGTLLVNRSL

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Crispr_ID: NZ_CP007028_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007028_9

1380866-1381425

Orphan

Consensus_repeat	Method
CTTTCAACTCCACACGGTACATTAGGAAC	CRISPRCasFinder
CTTTCAACTCCACACGGTACATTAGGAAC	CRT
CTTTCAACTCCACACGGTACATTAGGAAC	PILER-CR

8 spacers

The CRISPR arrays of NZ_CP007028_9

>merge|NZ_CP007028|9|1380866-1381425|CRISPRCasFinder,CRT,PILER-CR
ATTTCAACTCCACACGGTACATTAGGAACATTCCTGCTGTGGAAATTCGTGCTTGGTTAAAGCCCCTTTCAACTCCACACGGTACATTAGGAACTTATTTGCAAGAGGCTTACAACGATGTTCAAAGAGAGTCTTTCAACTCCACACGGTACATTAGGAACGCGTATACTTGCCACTTATATGGATGACCCTTTAACAACTTTCAACTCCACACGGTACATTAGGAACAAGGAGACCGCTGGGATACGCTCGCTTGGCAGTTCTACTTTCAACTCCACACGGTACATTAGGAACATACTCAACCCAAGCCATCCCACACCCTCAAACAACCACTTTCAACTCCACACGGTACATTAGGAACATCTCAAAATAGCTAAGAACCTAAACCAACGGAATACTTTCAACTCCACACGGTACATTAGGAACGAATTTCAAACTTTGATGTCAAGGCTACAAGATGCGCTTTCAACTCCACACGGTACATTAGGAACGCAGTAAGAACCGCTTCTTGAAATTGAGACACAATCTCAACTTTCAACTCCACACGGTACATTAGGAAC

>NZ_CP007028|9|9|1380866-1381425|CRISPRCasFinder
ATTTCAACTCCACACGGTACATTAGGAAC	ATTCCTGCTGTGGAAATTCGTGCTTGGTTAAAGCCC
CTTTCAACTCCACACGGTACATTAGGAAC	TTATTTGCAAGAGGCTTACAACGATGTTCAAAGAGAGT
CTTTCAACTCCACACGGTACATTAGGAAC	GCGTATACTTGCCACTTATATGGATGACCCTTTAACAA
CTTTCAACTCCACACGGTACATTAGGAAC	AAGGAGACCGCTGGGATACGCTCGCTTGGCAGTTCTA
CTTTCAACTCCACACGGTACATTAGGAAC	ATACTCAACCCAAGCCATCCCACACCCTCAAACAACCA
CTTTCAACTCCACACGGTACATTAGGAAC	ATCTCAAAATAGCTAAGAACCTAAACCAACGGAATA
CTTTCAACTCCACACGGTACATTAGGAAC	GAATTTCAAACTTTGATGTCAAGGCTACAAGATGCG
CTTTCAACTCCACACGGTACATTAGGAAC	GCAGTAAGAACCGCTTCTTGAAATTGAGACACAATCTCAA
CTTTCAACTCCACACGGTACATTAGGAAC

>NZ_CP007028|9|6|1380866-1381425|CRT
ATTTCAACTCCACACGGTACATTAGGAAC	ATTCCTGCTGTGGAAATTCGTGCTTGGTTAAAGCCC
CTTTCAACTCCACACGGTACATTAGGAAC	TTATTTGCAAGAGGCTTACAACGATGTTCAAAGAGAGT
CTTTCAACTCCACACGGTACATTAGGAAC	GCGTATACTTGCCACTTATATGGATGACCCTTTAACAA
CTTTCAACTCCACACGGTACATTAGGAAC	AAGGAGACCGCTGGGATACGCTCGCTTGGCAGTTCTA
CTTTCAACTCCACACGGTACATTAGGAAC	ATACTCAACCCAAGCCATCCCACACCCTCAAACAACCA
CTTTCAACTCCACACGGTACATTAGGAAC	ATCTCAAAATAGCTAAGAACCTAAACCAACGGAATA
CTTTCAACTCCACACGGTACATTAGGAAC	GAATTTCAAACTTTGATGTCAAGGCTACAAGATGCG
CTTTCAACTCCACACGGTACATTAGGAAC	GCAGTAAGAACCGCTTCTTGAAATTGAGACACAATCTCAA
CTTTCAACTCCACACGGTACATTAGGAAC

>NZ_CP007028|9|8|1380867-1381425|PILER-CR
TTTCAACTCCACACGGTACATTAGGAACA	TTCCTGCTGTGGAAATTCGTGCTTGGTTAAAGCCCC
TTTCAACTCCACACGGTACATTAGGAACT	TATTTGCAAGAGGCTTACAACGATGTTCAAAGAGAGTC
TTTCAACTCCACACGGTACATTAGGAACG	CGTATACTTGCCACTTATATGGATGACCCTTTAACAAC
TTTCAACTCCACACGGTACATTAGGAACA	AGGAGACCGCTGGGATACGCTCGCTTGGCAGTTCTAC
TTTCAACTCCACACGGTACATTAGGAACA	TACTCAACCCAAGCCATCCCACACCCTCAAACAACCAC
TTTCAACTCCACACGGTACATTAGGAACA	TCTCAAAATAGCTAAGAACCTAAACCAACGGAATAC
TTTCAACTCCACACGGTACATTAGGAACG	AATTTCAAACTTTGATGTCAAGGCTACAAGATGCGC
TTTCAACTCCACACGGTACATTAGGAACG	CAGTAAGAACCGCTTCTTGAAATTGAGACACAATCTCAAC
TTTCAACTCCACACGGTACATTAGGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007028.1\|WP_025306653.1\|1380340_1380814_-\|ribosome-maturation-factor-RimP	unknown	unknown	gnl\|CDD\|234627
NZ_CP007028.1\|WP_025306651.1\|1378114_1379374_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_CP007028.1\|WP_025306662.1\|1388558_1389128_-\|carbon-monoxide-dehydrogenase	unknown	unknown	gnl\|CDD\|251369
NZ_CP007028.1\|WP_025306645.1\|1371410_1372853_-\|RtcB-family-protein	unknown	unknown	gnl\|CDD\|376465
NZ_CP007028.1\|WP_025306649.1\|1377268_1377556_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370734
NZ_CP007028.1\|WP_025306660.1\|1385785_1387468_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP007028.1\|WP_025306659.1\|1384639_1385815_+\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NZ_CP007028.1\|WP_156916207.1\|1377146_1377296_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306663.1\|1389148_1389379_-\|ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|224067
NZ_CP007028.1\|WP_025306648.1\|1374558_1377150_+\|alanine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234701
NZ_CP007028.1\|WP_025306652.1\|1379375_1380347_-\|transcription-termination-factor-NusA	unknown	unknown	gnl\|CDD\|236410
NZ_CP007028.1\|WP_025306655.1\|1382187_1382691_+\|16S-rRNA-processing-protein-RimM	unknown	unknown	gnl\|CDD\|234650
NZ_CP007028.1\|WP_038532517.1\|1372869_1374126_+\|diaminopimelate-decarboxylase	unknown	unknown	gnl\|CDD\|273415
NZ_CP007028.1\|WP_025306650.1\|1377545_1378103_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|179647
NZ_CP007028.1\|WP_025306656.1\|1382797_1383160_+\|DUF1232-domain-containing-protein	unknown	unknown	gnl\|CDD\|377712
NZ_CP007028.1\|WP_025306661.1\|1387511_1388570_+\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|274090
NZ_CP007028.1\|WP_025306647.1\|1374140_1374464_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007028.1\|WP_025306658.1\|1384092_1384647_+\|DJ-1/PfpI-family-protein	unknown	unknown	gnl\|CDD\|153229
NZ_CP007028.1\|WP_025306657.1\|1383159_1384080_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NZ_CP007028.1\|WP_025306654.1\|1381888_1382173_+\|DUF2325-domain-containing-protein	unknown	unknown	gnl\|CDD\|378383

Protein	Function_ID	Function_description	E-value
NZ_CP007028.1\|WP_025306653.1\|1380340_1380814_-\|ribosome-maturation-factor-RimP	gnl\|CDD\|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	1.08538e-55
NZ_CP007028.1\|WP_025306651.1\|1378114_1379374_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	2.32968e-111
NZ_CP007028.1\|WP_025306662.1\|1388558_1389128_-\|carbon-monoxide-dehydrogenase	gnl\|CDD\|251369	pfam02552, CO_dh, CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit. This family consists of Carbon monoxide dehydrogenase I/II beta subunit EC:1.2.99.2 and acetyl-CoA synthase epsilon subunit. Carbon monoxide beta subunit catalyzes the reaction: CO + H2O + acceptor <=> CO2 + reduced acceptor.	2.46698e-62
NZ_CP007028.1\|WP_025306645.1\|1371410_1372853_-\|RtcB-family-protein	gnl\|CDD\|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	0
NZ_CP007028.1\|WP_025306649.1\|1377268_1377556_+\|hypothetical-protein	gnl\|CDD\|370734	pfam09876, DUF2103, Predicted metal-binding protein (DUF2103). This domain, found in various putative metal binding prokaryotic proteins, has no known function.	2.98395e-09
NZ_CP007028.1\|WP_025306660.1\|1385785_1387468_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.04702e-117
NZ_CP007028.1\|WP_025306659.1\|1384639_1385815_+\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	4.0992e-135
NZ_CP007028.1\|WP_025306663.1\|1389148_1389379_-\|ferredoxin-oxidoreductase	gnl\|CDD\|224067	COG1144, COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit [Energy production and conversion].	1.21894e-17
NZ_CP007028.1\|WP_025306648.1\|1374558_1377150_+\|alanine--tRNA-ligase	gnl\|CDD\|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NZ_CP007028.1\|WP_025306652.1\|1379375_1380347_-\|transcription-termination-factor-NusA	gnl\|CDD\|236410	PRK09202, nusA, transcription elongation factor NusA; Validated.	1.40233e-111
NZ_CP007028.1\|WP_025306655.1\|1382187_1382691_+\|16S-rRNA-processing-protein-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	1.02587e-28
NZ_CP007028.1\|WP_038532517.1\|1372869_1374126_+\|diaminopimelate-decarboxylase	gnl\|CDD\|273415	TIGR01048, Diaminopimelate_decarboxylase, diaminopimelate decarboxylase. This family consists of diaminopimelate decarboxylase, an enzyme which catalyzes the conversion of diaminopimelic acid into lysine during the last step of lysine biosynthesis. [Amino acid biosynthesis, Aspartate family].	0
NZ_CP007028.1\|WP_025306650.1\|1377545_1378103_-\|flavodoxin-family-protein	gnl\|CDD\|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	5.15197e-26
NZ_CP007028.1\|WP_025306656.1\|1382797_1383160_+\|DUF1232-domain-containing-protein	gnl\|CDD\|377712	pfam06803, DUF1232, Protein of unknown function (DUF1232). This family represents a conserved region of approximately 60 residues within a number of hypothetical bacterial and archaeal proteins of unknown function.	4.73318e-06
NZ_CP007028.1\|WP_025306661.1\|1387511_1388570_+\|molecular-chaperone-DnaJ	gnl\|CDD\|274090	TIGR02349, Chaperone_protein_DnaJ, chaperone protein DnaJ. This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.	5.16434e-141
NZ_CP007028.1\|WP_025306658.1\|1384092_1384647_+\|DJ-1/PfpI-family-protein	gnl\|CDD\|153229	cd03135, GATase1_DJ-1, Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. DJ-1 is involved in multiple physiological processes including cancer, Parkinson's disease and male fertility. It is unclear how DJ-1 functions in these. DJ-1 has been shown to possess chaperone activity. DJ-1 is preferentially expressed in the testis and moderately in other tissues; it is induced together with genes involved in oxidative stress response. The Drosophila homologue (DJ-1A) plays an essential role in oxidative stress response and neuronal maintenance. Inhibition of DJ-1A function through RNAi, results in the cellular accumulation of reactive oxygen species, organismal hypersensitivity to oxidative stress, and dysfunction and degeneration of dopaminergic and photoreceptor neurons. DJ-1 has lacks enzymatic activity and the catalytic triad of typical GATase1 domains, however it does contain the highly conserved cysteine located at the nucelophile elbow region typical of these domains. This cysteine been proposed to be a site of regulation of DJ-1 activity by oxidation. DJ-1 is a dimeric enzyme.	1.06208e-64
NZ_CP007028.1\|WP_025306657.1\|1383159_1384080_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	4.33781e-100
NZ_CP007028.1\|WP_025306654.1\|1381888_1382173_+\|DUF2325-domain-containing-protein	gnl\|CDD\|378383	pfam10087, DUF2325, Uncharacterized protein conserved in bacteria (DUF2325). Members of this family of hypothetical bacterial proteins have no known function.	4.83453e-23

>NZ_CP007028.1|WP_025306653.1|1380340_1380814_-|ribosome-maturation-factor-RimP
MQLDDKAIVQRVKEMVLPIVSKMGYKLFDVEFKPERGWVLRIIVDKEGGITVGDCEEISKRISALLDVEDIIPVSYMLEVSSPGLTRELTKAEHFSFFKGRLVRVVLREPIQNRRELIGRIEDVKDDVLVLKDKGTEELLHIPLSIIARANLEIEKW
>NZ_CP007028.1|WP_025306652.1|1379375_1380347_-|transcription-termination-factor-NusA
MVRNLKKLIEQVAKDKNLPEWLVEKALKNSIVLAIKKDRKIKNNLEVELTEDGIKVYQVRKGEKFPLDIVPEELDRIAAYAAKEEFLRELERADEERRYLEFIELEGEIVIGIVRRVLENGDLVVDLGKVMAILPKREQIPKESYKPGDRIKALLLKVIRKRGTYEIILSRTHPNFLRKLLEAEIPEIKEGEVEVLNIAREPGERAKVLVKAKDPRIDPVGLVVGLRGSKIAPVTQELSGERIDIIKYTDNIEELVKKSLAPAPVVDIRIDPNQKRVEVAVPKEKLSSAIGKRGVNVKLANRITGWYIDVMSEEDFKKLSQLS
>NZ_CP007028.1|WP_025306651.1|1378114_1379374_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MGLDLFVKKLVYGGYGLGEDKGKKFFIRYAAPKELVEVEVLKEKKDYTEAVVKTVKIGSQWRRTPPCKYYTHCGGCQWQHIEYQEQLRAKADILLESLERIGKIKLDSVNGILGSKEEFGYRTRVQFKIREGHLGFFAWGSGELVPIEECLLAHPRINQLIPSLKETARLIKELQEVHVFYSPHEDEFLLKLITISPMETQKLRKLKEHILPKEVVGLGNYTLLGGRFIKRAVVGREFTFVRSGRFILRVSNDSFFQVNHTLYEDFPKLVAEGEKVKRILELHSGVGFFSFWLSEHCEFLFGSDANQSAVKDAIYNAKLNQVSNVSFAHEKAIDTLKNHAGEVIDLLVLDPPREGLSEGEAKLIVQNKPKRIIYISCNPTTLARDLKVLTSGGYKIEGVHLVDNFPQTYHIESVVKITI
>NZ_CP007028.1|WP_025306650.1|1377545_1378103_-|flavodoxin-family-protein
MGKVLVLYDSRTGNTEKMAYLVAEGAKRVEGIEVRIKKVDDATREDVLWADGLAVGSPTHMGIISWKLKKFFDEELGELWGEIDGKIACAFSSSGGWGGGNEVACMSILTVLMNFGFLVFGVTDYVGKKFTLHYGAVVAGEPRSEEEKEACRRLGERLAQYVAIFFDGKKELLERIRTFEGKFKD
>NZ_CP007028.1|WP_025306649.1|1377268_1377556_+|hypothetical-protein
MGKHRKGKVKIEHHLLEGLEEYLKKLSSFSSVKSIIPGRIARQNKGIGSKGLFLKYETPTGYKLLYKNGTSVQEIFVVCDREKFLEEFKATFFNP
>NZ_CP007028.1|WP_156916207.1|1377146_1377296_+|hypothetical-protein
MKILLVESNLILASRVKNSLSGYDVRVGKDWRGVVDAQSLLWENTEKER
>NZ_CP007028.1|WP_025306648.1|1374558_1377150_+|alanine--tRNA-ligase
MSGNEIRELFLSFFESKGHTRVKSASLVPESDPTLLFTNAGMVPFKNVFLGLEKRPYKRAVSCQKCLRVSGKHNDLESVGYTSRHHTFFEMLGNFSFGDYFKREAILYAWEFVTEYLKLPKEKLYVSVFRDDEEAYRIWNEEVGLPSERIWRLGEEDNFWQMGDTGPCGPSSEIYVDRGEEYGEERFLEIWNLVFMQYNRDEKGNLTPLPNPNIDTGMGLERIASVLQGTKTNFEIDLIKPLIDFGQEISGKTYGENFEDTVAMRVIADHLRAITFAISDGVLPSNTARGYVIRRILRRALRFGYKLGIREPFLYKGVDVVVEVMKDAYPELLQTRAFVKGVVKAEEERFLHTFRNSMPVVEEFINTALEEGRRFLKGEEVFKLYDTYGFPLDLLEEIAKEKGLSLDMEGFEREMEIQRERARQNFKIQTKEVQPIYQHLKNIGRTSTFVGYEQYVAQSKVIALLKNGELVSELKEGEEGEVFLDITPFYAERGGQIGDTGTIESVDGLFVVDDTQSPVDGVISHKGKVVKGTIKVGDQVIASIDRERREDIKRNHTATHLLHSALRLVLGEHVRQAGSLVADKYLRFDFTHFQALSVDELKRVEELVNEQIRKNEPVIVEEKDYREAIKEGAIAIFEEKYGERVRVLSVGDFSKELCGGTHVSRTGEIGYFKIISESSIGAGLRRIVAKTGRWAVEEAFLESLTLKQVAQSLGVSTEEVLEGLSKLQERVKELERELQRVKSESARKQAKERIKEEGFGEYTLFYGVLEDVEGDLLRELADQFRQGRTKTVVFLASKREGKLSTLIALSKDLVGSLSAKELIKEVGKVLGGGGGGRDDLAQGGGTKPENFEKALELLKEKLR
>NZ_CP007028.1|WP_025306647.1|1374140_1374464_-|hypothetical-protein
MPHSTTDHIIELKLKKLYHKDKASIEELLNSRAGRNLLPYEIVFNDQVDWEKLKDSFPELSEYYHKACVIYSNYRYLIRRNKPLPTVKEKMKQEDVGKFFEALRALE
>NZ_CP007028.1|WP_038532517.1|1372869_1374126_+|diaminopimelate-decarboxylase
MLLKEYNPYLEYKNGELFLEGVSLKELAKEYGTPLYVYSASYIRDRIRAYKEAFPNALICYAVKANFNPHIVALTKEEGAGADVVSGGELYCALKAGVEPSKIVYAGVGKTLQEITFAVEKDILMFNVESHMELDVLNEVGERLGKKVRVAIRVNPDVDPRTHPYISTGMKKSKFGIDIKQAKEEYRYARSLKNLEVVGIHCHIGSQILDVSPYIEAVEKVVGLYEELIKDGFDIKYIDLGGGLGIKYQPDQANPEPEDLAKAIMPSLRGVQAKLILEPGRSIVGNAGILLTQVQFLKDKGHKHFVIVDAGMNDLIRPAIYSAYHHIVPVVERDVKYIKTDVVGPICETGDFLALDREIPYVERGDYLAVLSAGAYGFAMSSHYNARPKACELLVEKGKVKVIRRRETYEDIFNACFS
>NZ_CP007028.1|WP_025306645.1|1371410_1372853_-|RtcB-family-protein
MGLKEQLVQVQPFVYKLPENTIQGQKVPVYFYLSDRLFEILEEDAIRQAANAATLPGVKKAIYVMPDVHVGYGFPVGGVMATDPEEGIISPGSVGYDINCGVRLIATNLTADMVYPVRRELMNEILKNVPAGVGSTGKIKLTKSQMEEVAVKGARWAVEQGFGFLEDLEHIESGGALPNADPSKVSKEAYERGSDELGTVGSGNHFVEVQVVDEIYDEDIAERLGLKLGQVCIMVHSGSRGFGHQVCVDYLKVAKDALKKYNIDIPDMQLACMPFNSPEGQAYFSAMNSAANYAFANRQILGFLTADTIRRFFGLSWKDLGYRLIYDLAHNIAKLEKHKIDGKVLKLVVHRKGATRAFPPFNPEVPPAYRELGQPVLIPGDVGRYSFLLVGQDRSMEISFGTACHGAGRLMSRSKAKEFVRREGLEKVLGDLVVVARGKGTVAEEIPQAYKDVSEVVRVVDSLGIAKLVLRLKPLGTLKG
>NZ_CP007028.1|WP_025306654.1|1381888_1382173_+|DUF2325-domain-containing-protein
MRVVVLGGHDRLKARVEQIAKKYNISLKFINQETQQNIDSALACADWVIVFTSMSGHNMVKLAKRYAKERCIFCHSHGVCALERCILKILKEKG
>NZ_CP007028.1|WP_025306655.1|1382187_1382691_+|16S-rRNA-processing-protein-RimM
MEDFVVIGKIADTYGLNQELKVLAYLPPKEWKRIKKVYFKKRGGDYVPFELEKLRPHGEKWVLIKLKAVQSQEDATRFLGAKVFLPKENLPKRKKDEYYFFELEGLEVRSQEGKVLGRVDRLSSDKDRVYLEINDGKVIIPFIKEFVLEVKPEEGYLVINSLLEELF
>NZ_CP007028.1|WP_025306656.1|1382797_1383160_+|DUF1232-domain-containing-protein
MEEKLKKYYRDIDILELKALVERKLEKTPPTMEHVRNLILDVKLLLRILLDEDFPLKEDARKDMISALLYFVEPRDSIPDFIPIIGLWDDYKLVRYVKEKHKGEIDRYFESTPFFVANYF
>NZ_CP007028.1|WP_025306657.1|1383159_1384080_+|ABC-transporter-permease
MARFIIVRLVQGFLTLLGVTFISFLIIKLSPTDPFAQLKLNPQVSPQTIELLRKQYGLDQPLLIQYLKWLKSALVFDLGISLQYNAPVLDLIKERIGNTLLLTVPSALLSWLLAVPLGFLAGMKEGSLTDKAIRLFSYVFMSFPSFFLAFLLLLFLSKSGFFQLGGWQSLVVGVVTLTLISSAGLIRLMRSSVIEVLNSPMVQLLRSKGLKGWAFTRHILKNAMNPFTTLIGYEIAGLLSGAALVEIIVGWPGLGSLMLDAVLSTDLFLVMGGLYIGTIMLLIGNLLADLLLAYIDPRVREKEIIK
>NZ_CP007028.1|WP_025306658.1|1384092_1384647_+|DJ-1/PfpI-family-protein
MAKKVAILLAEGFEEVEAVAPIDVLRRGGVEVIIAGLTKDPVPSARNVKIVPDVSVDELNPDELDMVILPGGAGGVEKLKHDPRVERLVKAMEEKGKYISAICAAPTALAKFGILEGKKATVYPTLVEEIKPAVFVDMPVVEDERVITSQGPGTALEFGLKLLEKLEGKEKAREVAKRMLVKYD
>NZ_CP007028.1|WP_025306659.1|1384639_1385815_+|class-I-SAM-dependent-rRNA-methyltransferase
MIEVRLRPGVEKKIKAYFQWVYNLEIEEIKGSPEPGDLVKVLDSKKKFLGYGYINPNTKIMVRFLSFKEDEVPSKELIKERIKSALEYRKRLHLKSNAYRLVHSEGDFLPGLIVDVYDEYAVMEVTTYGMWKLTDWVKEALVEVLQPKGIYLRVSNYAMNIEGFSAEEGVLYGEVPERIKIWEEDLEFFVDVIKGQKTGFYLDQRRARKMIRDLVKPGDVCLDVFCHTGGFALSMKKKGASKVIAVDLSERALNLAKENAKLNQIDSIEWVEDNAFHFLRKLQKAGEKFDVVVIDPPSFARTRATVENAMRGYKELCIRGLQITKPGGYLAIYSCSFHIQREHLLSVILEACKDVKKQVRVVGESFQDLDHPWILQMPNTLYLKGIYLEVL
>NZ_CP007028.1|WP_025306660.1|1385785_1387468_-|ABC-transporter-ATP-binding-protein
MEHLIWVVKRLRNYYLYILLALFGVLLESVSTAGISLMVKKLVDEGMLLRSWEGLTFGTLLLLGLALAQQLGSFLVSYYTNAYAEKEAKELRRLVFEKLLRSSFLSVRGYSLAEYTTRVLSDLKLYRDLIGSSVVKLVRDPATVLLLFGVLLYRDWKLTLTLLALLPIIALSVEYFGRKKGKHLRRSQESLEKLVNKLGDVFRGYESIKTLPAQELLFGWFRDINEKAYRAGLRMALYSSFNSAFNYSVGYLATALLLFYGGLKVLEGSLTFGELLSYLTALMLIQMPLVETQKGIVEVKAGLPVVQRLRQVLELEEEMEKGVEFVGLKEGINVQRLSVSIDGRDILKGVSFSIRKGERVAVMGSTGSGKSTLLRVLCGFVPYEGQVYYDEKELREINLSTLRSKIAYLSQESFVLSGTVRENLLIANPNATEEEMWEALRLSACHFVESLDEVVDKESRMLSGGESQRLALARLFLKKPEVLLLDEATSALDAQTESFVLKNLFEKFPDTTFIVVAHRFSNILACQRALVLKDGEIIFDGEPKRAIEVFLSEDLQVDAF
>NZ_CP007028.1|WP_025306661.1|1387511_1388570_+|molecular-chaperone-DnaJ
MALKDYYQILGVDRNASKEEIKKAYRRLAKEWHPDVNPDPKAEEKFKEINEAYYVLSDEEKRRQYDQLLKSGDEKGYRDFMEYIQEFLESIWQGMRRTPKPKRGQDIRLRLELSLEEAYLGTEKLVEYERWIDCPQCGAKGYVGELVKEPCSACEGTGRRVSGIFSFPRPCSVCKGRGYIVKNPCPVCAGRGRVAKHSTVKVNIPPGTDEGDVLKVIGMGHQGERGGEPGDLYLRISLKPHPIFKKVGKDLHTEKLISFPLAVLGGTTKIKTLKGEELEIFIQPGTECGSTKTIPGMGFSAEGNLVITFRIEVPKNPSGKLKKLLTELAKELKEEGVEKPPTLLDNLKKLLS
>NZ_CP007028.1|WP_025306662.1|1388558_1389128_-|carbon-monoxide-dehydrogenase
MATLGPSGFSPYPVAVYEGVLNPPPGKALMFNEIVDEEIAMREAAKAMLTLPNATIFPGPQVLYAWNEEAKEKAKLVRKMAEVLNAKIIPMYDYRPKYPKIDPAVEINPNHPNLTIWHNKIKACIFVGVHCHYANVALKIIRAETDCFTIAMCGMAGHEDAMITLRDQHIEEMEKFIKIAEEVKRELGK
>NZ_CP007028.1|WP_025306663.1|1389148_1389379_-|ferredoxin-oxidoreductase
MYYVAEVINEECSKYNCKQCTLFCPEPNTLMYSDEEHHAYVNTERCKGCALCVYVCSTLLKRNAIRMVMPEVHAGK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007028_6	6.19\|906783\|36\|NZ_CP007028\|CRT,PILER-CR	906783-906818	36	MN693876	Marine virus AFVG_250M699, complete genome	15414-15449	11	0.694
NZ_CP007028_6	6.19\|906783\|36\|NZ_CP007028\|CRT,PILER-CR	906783-906818	36	KT997855	Uncultured Mediterranean phage uvDeep-CGR2-AD12-C183, complete genome	14385-14420	11	0.694
NZ_CP007028_6	6.20\|906849\|36\|NZ_CP007028\|CRT,PILER-CR	906849-906884	36	MN693876	Marine virus AFVG_250M699, complete genome	15414-15449	11	0.694
NZ_CP007028_6	6.20\|906849\|36\|NZ_CP007028\|CRT,PILER-CR	906849-906884	36	KT997855	Uncultured Mediterranean phage uvDeep-CGR2-AD12-C183, complete genome	14385-14420	11	0.694

1. spacer 6.19|906783|36|NZ_CP007028|CRT,PILER-CR matches to MN693876 (Marine virus AFVG_250M699, complete genome) position: , mismatch: 11, identity: 0.694

tttgtttgcgaaagaaagcgtgggtgcggaggtgta	CRISPR spacer
gccaccagtaaaagaaatagtgggtgcggaggtgta	Protospacer
 ..... *..*******  *****************

2. spacer 6.19|906783|36|NZ_CP007028|CRT,PILER-CR matches to KT997855 (Uncultured Mediterranean phage uvDeep-CGR2-AD12-C183, complete genome) position: , mismatch: 11, identity: 0.694

tttgtttgcgaaagaaagcgtgggtgcggaggtgta	CRISPR spacer
gccaccagtaaaagaaatagtgggtgcggaggtgta	Protospacer
 ..... *..*******  *****************

3. spacer 6.20|906849|36|NZ_CP007028|CRT,PILER-CR matches to MN693876 (Marine virus AFVG_250M699, complete genome) position: , mismatch: 11, identity: 0.694

tttgtttgcgaaagaaagcgtgggtgcggaggtgta	CRISPR spacer
gccaccagtaaaagaaatagtgggtgcggaggtgta	Protospacer
 ..... *..*******  *****************

4. spacer 6.20|906849|36|NZ_CP007028|CRT,PILER-CR matches to KT997855 (Uncultured Mediterranean phage uvDeep-CGR2-AD12-C183, complete genome) position: , mismatch: 11, identity: 0.694

tttgtttgcgaaagaaagcgtgggtgcggaggtgta	CRISPR spacer
gccaccagtaaaagaaatagtgggtgcggaggtgta	Protospacer
 ..... *..*******  *****************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

199652 : 209156

Marinitoga_camini_virus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025305441.1\|199652_201302_+	ATP-binding protein	A0A139ZPI2	Marinitoga_camini_virus	2.3e-36	26.6
WP_025305442.1\|201273_202473_+	N-acetylmuramoyl-L-alanine amidase	A0A2H4JCM7	uncultured_Caudovirales_phage	6.0e-18	30.7
WP_025305443.1\|202423_203083_-	7-carboxy-7-deazaguanine synthase QueE	J9PV61	Bacillus_phage	3.8e-22	34.9
WP_025305444.1\|203046_205302_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	3.2e-28	25.8
WP_025305445.1\|206240_207515_+	glutamate-1-semialdehyde 2,1-aminomutase	A0A1V0SKB7	Klosneuvirus	1.6e-08	24.9
WP_025305446.1\|207506_209156_-	transglycosylase SLT domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	8.9e-20	41.8

DBSCAN-SWA_2

888579 : 939302

Tupanvirus(22.22%)

integrase,transposase,protease

attL 880923:880938|attR 907840:907855

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
880923:880938	attL	NA	NA	NA	NA
WP_025306151.1\|888579_889338_+\|protease	hydrogenase maturation protease	NA	NA	NA	NA
WP_025306152.1\|889352_889571_+	hypothetical protein	NA	NA	NA	NA
WP_025306153.1\|889570_890752_+	hypothetical protein	NA	NA	NA	NA
WP_025306154.1\|890735_891563_+	NifU family protein	NA	NA	NA	NA
WP_025306155.1\|891559_892540_+	hypothetical protein	NA	NA	NA	NA
WP_025306156.1\|892529_892871_-	4-vinyl reductase	NA	NA	NA	NA
WP_025306157.1\|892867_894061_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_025306158.1\|894075_895230_-	sulfate adenylyltransferase	A0A2K9L0F0	Tupanvirus	9.8e-42	30.3
WP_025306159.1\|895226_895973_-	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_025306160.1\|895972_896737_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_025306161.1\|896729_897023_-	hypothetical protein	NA	NA	NA	NA
WP_038532140.1\|897003_899646_-	phosphoadenylyl-sulfate reductase	NA	NA	NA	NA
WP_025306162.1\|899789_901148_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_025306163.1\|901101_901605_-	hypothetical protein	NA	NA	NA	NA
WP_169727092.1\|901903_902014_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_156916201.1\|902237_903056_+	hypothetical protein	NA	NA	NA	NA
WP_051402152.1\|903099_904755_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_025306166.1\|904881_905913_+	hypothetical protein	NA	NA	NA	NA
WP_025306167.1\|907003_909262_-	CRISPR-associated helicase/endonuclease Cas3	NA	NA	NA	NA
907840:907855	attR	NA	NA	NA	NA
WP_025306168.1\|909254_909989_-	type I-B CRISPR-associated protein Cas5	NA	NA	NA	NA
WP_025306169.1\|909988_910882_-	type I-B CRISPR-associated protein Cas7/Csh2	NA	NA	NA	NA
WP_025306170.1\|910878_912606_-	TIGR02556 family CRISPR-associated protein	NA	NA	NA	NA
WP_169727093.1\|912598_913252_-	CRISPR-associated endoribonuclease Cas6	NA	NA	NA	NA
WP_025306172.1\|913846_914584_+	AAA family ATPase	Q8JL10	Natrialba_phage	1.5e-14	32.4
WP_025306173.1\|914565_914850_+	hypothetical protein	NA	NA	NA	NA
WP_038532144.1\|915445_916189_-	hypothetical protein	M1I5Z5	Acanthocystis_turfacea_Chlorella_virus	6.0e-08	29.0
WP_025306176.1\|916185_917088_-	MoxR family ATPase	NA	NA	NA	NA
WP_025306177.1\|917132_918431_-	TrpB-like pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_025306178.1\|918663_920031_+	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_025306122.1\|920080_921757_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_025306179.1\|921897_922458_-	hypothetical protein	NA	NA	NA	NA
WP_025306180.1\|922797_923298_+	DUF29 domain-containing protein	NA	NA	NA	NA
WP_025306181.1\|923344_925177_+	hypothetical protein	NA	NA	NA	NA
WP_169727094.1\|925173_925587_-	hypothetical protein	NA	NA	NA	NA
WP_156916202.1\|926761_927295_+	DUF4411 family protein	NA	NA	NA	NA
WP_025306184.1\|927325_928414_+	helix-turn-helix domain-containing protein	S5MAC0	Brevibacillus_phage	1.4e-05	36.8
WP_025306185.1\|928547_929135_+	hypothetical protein	NA	NA	NA	NA
WP_025306186.1\|929280_929631_+	gamma-glutamylcyclotransferase	R4JE05	Pseudoalteromonas_phage	7.6e-06	34.2
WP_025306187.1\|929684_931112_+	hypothetical protein	NA	NA	NA	NA
WP_084326319.1\|931313_932816_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_169727082.1\|932843_933059_+	hypothetical protein	NA	NA	NA	NA
WP_025306189.1\|934261_935050_+\|transposase	transposase	F9VHY8	Thermus_phage	3.1e-87	59.4
WP_025306190.1\|935143_936115_+	thioredoxin-disulfide reductase	A0A2K9L162	Tupanvirus	9.8e-43	33.3
WP_025306191.1\|936115_937390_+	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	9.5e-38	36.3
WP_025306192.1\|937389_938145_+	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_025306193.1\|938146_938560_+	NUDIX hydrolase	G3MA14	Bacillus_virus	2.5e-11	36.3
WP_025306194.1\|938550_938784_+	hypothetical protein	NA	NA	NA	NA
WP_025306195.1\|938780_939302_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA

DBSCAN-SWA_3

1341299 : 1349139

uncultured_Mediterranean_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025306609.1\|1341299_1342094_-	site-specific DNA-methyltransferase	A0A1B1INV8	uncultured_Mediterranean_phage	2.0e-22	36.9
WP_025306610.1\|1342093_1342819_-	pyridoxine 5'-phosphate synthase	NA	NA	NA	NA
WP_025306611.1\|1342821_1343637_-	thiazole biosynthesis adenylyltransferase ThiF	A0A291ATS8	Pandoravirus	4.3e-07	31.0
WP_025306612.1\|1343659_1344055_-	S-adenosylmethionine decarboxylase	A0A1D7SEZ2	Cyanophage	9.8e-18	53.1
WP_025306613.1\|1344151_1344610_+	RsmD family RNA methyltransferase	NA	NA	NA	NA
WP_025306614.1\|1344602_1345085_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.6e-20	37.1
WP_025306615.1\|1345081_1345522_-	glycine cleavage system protein H	NA	NA	NA	NA
WP_025306616.1\|1345651_1346056_+	septal ring lytic transglycosylase RlpA family protein	F5B3X9	Synechococcus_phage	1.4e-14	46.4
WP_025306617.1\|1346039_1346840_-	radical SAM protein	NA	NA	NA	NA
WP_025306618.1\|1346811_1347678_-	hypothetical protein	NA	NA	NA	NA
WP_025306619.1\|1347643_1348582_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	8.9e-09	26.3
WP_025306620.1\|1348578_1349139_-	GTP cyclohydrolase I FolE	L7TN23	Rhizobium_phage	2.0e-40	56.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007028

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection