CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP007001	Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence	1 crisprs	NA	1	2	0
NZ_CP006999	Campylobacter fetus subsp. venerealis cfvi03/293 chromosome, complete genome	2 crisprs	c2c9_V-U4,DEDDh,cas3,cas14j,cas6,csx23,cas10,csm3gr7,csx19	0	3	1
NZ_CP007002	Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviP3, complete sequence	0 crisprs	NA	0	0	0
NZ_CP007000	Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP1, complete sequence	0 crisprs	cas14j,c2c9_V-U4,Cas9_archaeal	0	0	2

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007001_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007001_1

34998-35168

Orphan

Consensus_repeat	Method
GTTTTTAACGACAAAAAATACGTTTTTT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP007001_1

>merge|NZ_CP007001|1|34998-35168|CRISPRCasFinder
GTTTTTAACAAGAAAAAATTCGGTTTTAGAGATAAATTTAAATATCAAAAGCCCTAAAATAGGCAATTTGGTATAAAAAGAAAAATGTAGTTTTTAACGACAAAAAATACGTTTTTTAAACTCTTTTTAACGACAAAAAATACGTTTTTAACGACAAAAAATACGTTTTTT

>NZ_CP007001|1|1|34998-35168|CRISPRCasFinder
GTTTTTAACAAGAAAAAATTCGGTTTTA	GAGATAAATTTAAATATCAAAAGCCCTAAAATAGGCAATTTGGTATAAAAAGAAAAATGTA
GTTTTTAACGACAAAAAATACGTTTTTT	AAACTCTTTTTAACGACAAAAAATAC
GTTTTTAACGACAAAAAATACGTTTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007001.1\|WP_025370506.1\|27144_28083_-\|P-type-conjugative-transfer-protein-VirB9	unknown	unknown	gnl\|CDD\|274296
NZ_CP007001.1\|WP_025370508.1\|29073_30180_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377390
NZ_CP007001.1\|WP_158005108.1\|28900_29077_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234578
NZ_CP007001.1\|WP_025370507.1\|28232_28904_-\|type-IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|377310
NZ_CP007001.1\|WP_025370510.1\|30940_33694_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273346
NZ_CP007001.1\|WP_025370512.1\|34079_34355_-\|EexN-family-lipoprotein	unknown	unknown	unknown
NZ_CP007001.1\|WP_025370511.1\|33700_34018_-\|TrbC/VirB2-family-protein	unknown	unknown	gnl\|CDD\|368210
NZ_CP007001.1\|WP_158005107.1\|28072_28231_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007001.1\|WP_025370513.1\|34578_34791_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|259851
NZ_CP007001.1\|WP_025370509.1\|30183_30930_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369643

Protein	Function_ID	Function_description	E-value
NZ_CP007001.1\|WP_025370506.1\|27144_28083_-\|P-type-conjugative-transfer-protein-VirB9	gnl\|CDD\|274296	TIGR02781, Protein_virB9, P-type conjugative transfer protein VirB9. The VirB9 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in a type IV secretion system . VirB9 is a homolog of the F-type conjugative transfer system TraK protein (which is believed to be an outer membrane pore-forming secretin, TIGR02756) as well as the Ti system TrbG protein. [Cellular processes, Conjugation].	8.67614e-70
NZ_CP007001.1\|WP_158005108.1\|28900_29077_-\|hypothetical-protein	gnl\|CDD\|234578	PRK00022, lolB, lipoprotein localization protein LolB.	0.0034121
NZ_CP007001.1\|WP_025370507.1\|28232_28904_-\|type-IV-secretion-system-protein	gnl\|CDD\|377310	pfam04335, VirB8, VirB8 protein. VirB8 is a bacterial virulence protein with cytoplasmic, transmembrane, and periplasmic regions. It is thought that it is a primary constituent of a DNA transporter. The periplasmic region interacts with VirB9, VirB10, and itself. This family also includes the conjugal transfer protein family TrbF, a family of proteins known to be involved in conjugal transfer. The TrbF protein is thought to compose part of the pilus required for transfer. This domain has a similar fold to the NTF2 protein.	1.55215e-51
NZ_CP007001.1\|WP_025370510.1\|30940_33694_-\|hypothetical-protein	gnl\|CDD\|273346	TIGR00929, CAG_pathogenicity_island_protein_23, type IV secretion/conjugal transfer ATPase, VirB4 family. Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).	0
NZ_CP007001.1\|WP_025370511.1\|33700_34018_-\|TrbC/VirB2-family-protein	gnl\|CDD\|368210	pfam04956, TrbC, TrbC/VIRB2 family. Conjugal transfer protein, TrbC has been identified as a subunit of the pilus precursor in bacteria. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains several VIRB2 type IV secretion proteins. The virB2 gene encodes a putative type IV secretion system and is known to be a pathogenicity factor in Bartonella species.	1.65977e-09
NZ_CP007001.1\|WP_025370508.1\|29073_30180_-\|hypothetical-protein	gnl\|CDD\|377390	pfam04610, TrbL, TrbL/VirB6 plasmid conjugal transfer protein.	5.41621e-10
NZ_CP007001.1\|WP_025370509.1\|30183_30930_-\|hypothetical-protein	gnl\|CDD\|369643	pfam07996, T4SS, Type IV secretion system proteins. Members of this family are components of the type IV secretion system. They mediate intracellular transfer of macromolecules via a mechanism ancestrally related to that of bacterial conjugation machineries.	9.3643e-26
NZ_CP007001.1\|WP_025370513.1\|34578_34791_+\|hypothetical-protein	gnl\|CDD\|259851	cd00569, HTH_Hin_like, Helix-turn-helix domain of Hin and related proteins. This domain model summarizes a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed helical bundle. The principal DNA-protein interface is formed by the third helix, the recognition helix, inserting itself into the major groove of the DNA. A diverse array of HTH domains participate in a variety of functions that depend on their DNA-binding properties. HTH_Hin represents one of the simplest versions of the HTH domains; the characterization of homologous relationships between various sequence-diverse HTH domain families remains difficult. The Hin recombinase induces the site-specific inversion of a chromosomal DNA segment containing a promoter, which controls the alternate expression of two genes by reversibly switching orientation. The Hin recombinase consists of a single polypeptide chain containing a C-terminal DNA-binding domain (HTH_Hin) and a catalytic domain.	0.000370561

>NZ_CP007001.1|WP_025370513.1|34578_34791_+|hypothetical-protein
MQKKNTLPIEITKIKTEIARDLGLSRATLYLWKNTRPKLYEIIMQYYGVSENIPTQDEQKNKNPYNQVHL
>NZ_CP007001.1|WP_025370512.1|34079_34355_-|EexN-family-lipoprotein
MTKIVAGGILVVGLLSLTGCFEQEIKTTEYFKTHPDEMEKVITKCKKAEKMTDGQKQECENAFKAQAMLNHFKPASRGLFEDEPQDKNTTK
>NZ_CP007001.1|WP_025370511.1|33700_34018_-|TrbC/VirB2-family-protein
MLGGGSLNSKNSALKTLTIFAALFVAFLIFPTDLLAAGGLDKAKTLLDKVIEWLNYLSIGVVTIAILVVGYKVLFGGQTIRECTPIIIGAIIIASAATVANLLMS
>NZ_CP007001.1|WP_025370510.1|30940_33694_-|hypothetical-protein
MGEEVIYKGLTRPAMVFGVPITPLFFVCALLALLALYINLAISALIFPAVFIMKEIAKKDEFIFRLLFLKLKFFSNPASKRFYQIKTYNGSSYSVMPLNFDYPKISVIGIDKNPNFEKFIPYQTLIDNVVITKDYDLLTTWEIDGVMFEVESDSDIAVSKERLNTLFRSFASEPISFYFHNCRLAADEKLEANFNNEFLKKLNDKYFESFQKGSSNKNRLFLTAIYTPLDRVTRSSFKKDSVEKRIRELDRYLNKMQEYCGNIEAKLNSFGSKRLGIYTKDNAQYSSQLEFYNYLISGKMSPVRVSNAPLFGYLNGNLDSIMFSNSAAQLNLNTGEKRFAKAIEIKDYTQFSYSGMLDILMYLKVEYTITQSFTPMAKSEAQADLTKQKKQLISSEDDAVSQVMELEHALDELSSGSLCFGKYHFSVIVYANSVKEVEQSTNLVITTLSNLGFLTSVANIALPATYFAQFPANFGIRPRIHTISSKNYSSLIALHNFSSGKKDKNCWGDAVTLLKTPNNQPYYFNFHETPAGKDSFGDFLLANTLVIGKSGGGKTVLMNFLLDQLCKYADVNSFPNDVPMEKRKATFFYLDKDKGAIGNIVALGGKYITIDAGHPTGFNPFMVENTAENVRKLQVLMKMLVTRNNEILTTLEEKNLNNAVESIMNNFNKDERKFGISLMLEHLYAKNEEVNSLRSRLELWSKKGKFGWIFDNENDELDFSDDSINVYGIDGTDLLKDKEISGMVSFYILWRIMDLTDGRRFALFIDEAWDWISNSVVAEEVHNKEKTIRKLNGFLVLGTQSVEDFAKSNIATAILEQSATILLLSNPKAKEEDYCGKLNLTQEEYLFAKNTLPDEYKFLIKKGVDERTIANIDLSKIGKTYLKILSTGKVYVEAIENINKQPLSYDEKFHKIQELYR
>NZ_CP007001.1|WP_025370509.1|30183_30930_-|hypothetical-protein
MKAINKIVLVSLVAANVAFASGIPVVDAAANAQIMQQNIKQVLEWSKEAKRWTDTALHYKSQLEAYAKELEAQSGIRDAVSFLQDAKDIYEEAKATGQNLSEIRDFVSDAANIKNSLSSKAKELMNKYFEYDRCVRYSENKQQNICYQKQAAVVDNIIFLNERSNNISSYTKDLNKLAKKLKNSKDVKESADIGNAIQLKVALLQAEKIQIDLMNDKKERNKEVIEEREKAEALQQWNARANKELFKD
>NZ_CP007001.1|WP_025370508.1|29073_30180_-|hypothetical-protein
MGLDAEQLKNIEGSATDLRDLIIAMGKKIDGTNGTGFINEISGAFSTNFQDYILGFKIIISVWLTAWIIYEGLQIAYGRNNKNVKDFMWDSFMKFVFISVCLYPDVFTNMLKNALDGIREYTLGNGRSSNLYELLGDFAYNVSKATNIMTTSSGFFNIFSDKPNAIVAYLSAIICYIGFFVGAVPVLITLSINSLSFYLLAAVIPIMFFCLIFGFLKNVFTQWMTMMISNIFTLVFVTLFCSSAFNYILPKTQILVSDAEAVNSFFIGGAFIFYGILLKVFITLATSMAQNLTQVSMEGAARVGLMQGAAMTGAGVGLGAAAALKYGKYVGGGWINPATNTATAKIGEFVGKMGAKGFHKFNQWRNAK
>NZ_CP007001.1|WP_158005108.1|28900_29077_-|hypothetical-protein
MKNLIVCVMALILAGCATTSQKLQTNATQNKTWAEMFDNNSWLAVNSTKFTENNKVIK
>NZ_CP007001.1|WP_025370507.1|28232_28904_-|type-IV-secretion-system-protein
MSKEYDKQKSMEYEASIRYLIEKSNRRAWLVAFLSFIVAVLSIVAVTLLTPLKSVEPYVIRVNDTTGVVDIITSVKREDLLQNEALDKYFVSTYIKTREGYYYDLLQQDYVKTQILSSPKVSEEYTALYSGDKARNEILKNKFEVKVHINSVVLGESAGIKTATIRFKEETIDLSSKASNMASKIATLSYDYSPDDLVQEQERLENPLGFKVLTYRIDMEIGK
>NZ_CP007001.1|WP_158005107.1|28072_28231_-|hypothetical-protein
MSDLGIFKLGRKDGRMSVDAPSVEATKSAKIIKDMSTKQDILERQGEIINVK
>NZ_CP007001.1|WP_025370506.1|27144_28083_-|P-type-conjugative-transfer-protein-VirB9
MLSSHKNLGFLVALLLLASTQTLALNIPKSSKFDTRITYASYNAQDVYLVKAKNGYVSMLQFAKDERIVNIATGFSDGWELIDRENFLFIKPKAYVAQPAEQEKMVDDEGNQVEFNQSLVIQPNEKDWKTNLIVTTNERIYVFDLVLEQEKINYKIEFAYPEDKIIAKKAQEAIKENVKLKEDIKKDLEKTAIPRNWKFYMHINEGSETIAPNFAYDDGIFTYIGFDNTKTIPSVFMYEEIDGKPQESILNTHIKKDGLFDVLVVHKTAKQILLRSGNKLVGIKNDGYAKNPLDTARTTISDKVEREIIDHE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP007001_1	1.1\|35026\|61\|NZ_CP007001\|CRISPRCasFinder	35026-35086	61	NZ_CP007001.1	34809-34869	1	0.984

1. spacer 1.1|35026|61|NZ_CP007001|CRISPRCasFinder matches to position: 34809-34869, mismatch: 1, identity: 0.984

gagataaatttaaatatcaaaagccctaaaataggcaatttggtataaaaagaaaaatgt	CRISPR spacer
gagataaatttaaatatcaaaagccctaaaataggcaatttggtataaaaagaaaaatgt	Protospacer
************************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP008811	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence	35749-35774	0	1.0
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP007001	Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence	35115-35140	0	1.0
NZ_CP007001_1	1.1\|35026\|61\|NZ_CP007001\|CRISPRCasFinder	35026-35086	61	NZ_CP007001	Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence	34809-34869	1	0.984
NZ_CP007001_1	1.1\|35026\|61\|NZ_CP007001\|CRISPRCasFinder	35026-35086	61	NZ_CP007001	Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence	35026-35086	1	0.984
NZ_CP007001_1	1.1\|35026\|61\|NZ_CP007001\|CRISPRCasFinder	35026-35086	61	NZ_CP008811	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence	35803-35863	2	0.967
NZ_CP007001_1	1.1\|35026\|61\|NZ_CP007001\|CRISPRCasFinder	35026-35086	61	NZ_CP008811	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence	36075-36135	2	0.967
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP008811	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence	36021-36046	3	0.885
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP008811	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence	35728-35753	4	0.846
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP008811	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence	35999-36024	4	0.846
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP007001	Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence	35136-35161	4	0.846
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP008811	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence	35782-35807	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP008811	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence	36054-36079	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP007001	Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence	34865-34890	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP007001	Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence	35082-35107	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_LN890334	Leuconostoc gelidum subsp. gasicomitatum KG16-1 isolate LEKG1 plasmid IV, complete sequence	3970-3995	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP026848	Weissella koreensis strain WiKim0080 plasmid pWKW_1, complete sequence	31037-31062	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP027769	Tetragenococcus halophilus strain LMG 26042 plasmid pTHF, complete sequence	12574-12599	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP042376	Leuconostoc carnosum strain CBA3620 plasmid unnamed2, complete sequence	33204-33229	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP015248	Leuconostoc suionicum strain DSM 20241 plasmid unnamed, complete sequence	5416-5441	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NC_022603	Carnobacterium inhibens subsp. gilichinskyi plasmid pWNCR64, complete sequence	51843-51868	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP029967	Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence	14649-14674	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NC_049978	IAS virus, complete genome	61445-61470	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_LR135279	Enterococcus faecium isolate E6975 plasmid 2	113888-113913	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	NZ_CP040704	Enterococcus faecium strain HOU503 plasmid p1, complete sequence	25682-25707	5	0.808
NZ_CP007001_1	1.2\|35115\|26\|NZ_CP007001\|CRISPRCasFinder	35115-35140	26	MK075006	Staphylococcus phage phiSP119-3, complete genome	4122-4147	5	0.808

1. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP008811 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence) position: , mismatch: 0, identity: 1.0

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaactctttttaacgacaaaaaatac	Protospacer
**************************

2. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP007001 (Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence) position: , mismatch: 0, identity: 1.0

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaactctttttaacgacaaaaaatac	Protospacer
**************************

3. spacer 1.1|35026|61|NZ_CP007001|CRISPRCasFinder matches to NZ_CP007001 (Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence) position: , mismatch: 1, identity: 0.984

gagataaatttaaatatcaaaagccctaaaataggcaatttggtataaaaagaaaaatgt	CRISPR spacer
gagataaatttaaatatcaaaagccctaaaataggcaatttggtataaaaagaaaaatgt	Protospacer
************************************************************

4. spacer 1.1|35026|61|NZ_CP007001|CRISPRCasFinder matches to NZ_CP007001 (Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence) position: , mismatch: 1, identity: 0.984

gagataaatttaaatatcaaaagccctaaaataggcaatttggtataaaaagaaaaatgt	CRISPR spacer
gagataaatttaaatatcaaaagccctaaaataggcaatttggtataaaaagaaaaatgt	Protospacer
************************************************************

5. spacer 1.1|35026|61|NZ_CP007001|CRISPRCasFinder matches to NZ_CP008811 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence) position: , mismatch: 2, identity: 0.967

gagataaatttaaatatcaaaagccctaaaataggcaatttggtataaaaagaaaaatgt	CRISPR spacer
gatataaatttaaatatcaaaagccctaaaataggcaatttggtataaaaagaaaaatgt	Protospacer
** *********************************************************

6. spacer 1.1|35026|61|NZ_CP007001|CRISPRCasFinder matches to NZ_CP008811 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence) position: , mismatch: 2, identity: 0.967

gagataaatttaaatatcaaaagccctaaaataggcaatttggtataaaaagaaaaatgt	CRISPR spacer
gatataaatttaaatatcaaaagccctaaaataggcaatttggtataaaaagaaaaatgt	Protospacer
** *********************************************************

7. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP008811 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence) position: , mismatch: 3, identity: 0.885

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaactctttttaacgacaaaaaaata	Protospacer
***********************

8. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP008811 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence) position: , mismatch: 4, identity: 0.846

aaactctttttaacgacaaaaaatac	CRISPR spacer
aatacgtttttaacgacaaaaaatac	Protospacer
**  . ********************

9. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP008811 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence) position: , mismatch: 4, identity: 0.846

aaactctttttaacgacaaaaaatac	CRISPR spacer
aatacgtttttaacgacaaaaaatac	Protospacer
**  . ********************

10. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP007001 (Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence) position: , mismatch: 4, identity: 0.846

aaactctttttaacgacaaaaaatac	CRISPR spacer
aatacgtttttaacgacaaaaaatac	Protospacer
**  . ********************

11. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP008811 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
atgtagtttttaacgacaaaaaatac	Protospacer
* ..  ********************

12. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP008811 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
atgtagtttttaacgacaaaaaatac	Protospacer
* ..  ********************

13. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP007001 (Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
atgtagtttttaacgacaaaaaatac	Protospacer
* ..  ********************

14. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP007001 (Campylobacter fetus subsp. venerealis cfvi03/293 plasmid pCfviMP2, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
atgtagtttttaacgacaaaaaatac	Protospacer
* ..  ********************

15. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_LN890334 (Leuconostoc gelidum subsp. gasicomitatum KG16-1 isolate LEKG1 plasmid IV, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaagtctttttaacggcaaaaaaata	Protospacer
*** ***********.*******

16. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP026848 (Weissella koreensis strain WiKim0080 plasmid pWKW_1, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaagtctttttaacggcaaaaaaata	Protospacer
*** ***********.*******

17. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP027769 (Tetragenococcus halophilus strain LMG 26042 plasmid pTHF, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaagtctttttaacggcaaaaaaatg	Protospacer
*** ***********.*******

18. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP042376 (Leuconostoc carnosum strain CBA3620 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaagtctttttaacggcaaaaaaata	Protospacer
*** ***********.*******

19. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP015248 (Leuconostoc suionicum strain DSM 20241 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaagtctttttaacggcaaaaaaata	Protospacer
*** ***********.*******

20. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NC_022603 (Carnobacterium inhibens subsp. gilichinskyi plasmid pWNCR64, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaagtctttttaacggcaaaaaaata	Protospacer
*** ***********.*******

21. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP029967 (Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaagtctttttaacggcaaaaaaata	Protospacer
*** ***********.*******

22. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NC_049978 (IAS virus, complete genome) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaactctttttaatgataaaaaactt	Protospacer
*************.**.******. .

23. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_LR135279 (Enterococcus faecium isolate E6975 plasmid 2) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaagtctttttaacggcaaaaaaatg	Protospacer
*** ***********.*******

24. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to NZ_CP040704 (Enterococcus faecium strain HOU503 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
aaagtctttttaacggcaaaaaaatg	Protospacer
*** ***********.*******

25. spacer 1.2|35115|26|NZ_CP007001|CRISPRCasFinder matches to MK075006 (Staphylococcus phage phiSP119-3, complete genome) position: , mismatch: 5, identity: 0.808

aaactctttttaacgacaaaaaatac	CRISPR spacer
ttcctctttttatcgtcaaaaaatac	Protospacer
   ********* ** **********

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP006999

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP006999_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006999_1

656028-656257

Orphan

Consensus_repeat	Method
TAGTTTGCTAATGACAATGTTTGTGTTGAAAC	PILER-CR
GTTTGCTAATGACAATGTTTGTGTTGAAAC	CRISPRCasFinder
GTTTGCTAATGACAATGTTTGTGTTGAAAC	CRT

3 spacers

The CRISPR arrays of NZ_CP006999_1

>merge|NZ_CP006999|1|656028-656257|PILER-CR,CRISPRCasFinder,CRT
TAGTTTGCTAATGACAATGTTTGTGTTGAAACAGAACTGTTTTAACCTCACTTCCATCAATCTCTTTTGTTTGCTAATGACAATGTTTGTGTTTAAACCAGTATGCCATTTGATTCTAGTTCGCCTATAGCTCTGTTTGCTAATGACAATGTTTGTGTTGAAACCATCCTCCTTTTAATTTATTACATTTAAACAATTTAGTTTGCTAATGACAATGTTTGTGTTGAAAC

>NZ_CP006999|1|1|656028-656257|PILER-CR
TAGTTTGCTAATGACAATGTTTGTGTTGAAAC	AGAACTGTTTTAACCTCACTTCCATCAATCTCTT
TTGTTTGCTAATGACAATGTTTGTGTTTAAAC	CAGTATGCCATTTGATTCTAGTTCGCCTATAGCT
CTGTTTGCTAATGACAATGTTTGTGTTGAAAC	CATCCTCCTTTTAATTTATTACATTTAAACAATT
TAGTTTGCTAATGACAATGTTTGTGTTGAAAC

>NZ_CP006999|1|1|656030-656257|CRISPRCasFinder
GTTTGCTAATGACAATGTTTGTGTTGAAAC	AGAACTGTTTTAACCTCACTTCCATCAATCTCTTTT
GTTTGCTAATGACAATGTTTGTGTTTAAAC	CAGTATGCCATTTGATTCTAGTTCGCCTATAGCTCT
GTTTGCTAATGACAATGTTTGTGTTGAAAC	CATCCTCCTTTTAATTTATTACATTTAAACAATTTA
GTTTGCTAATGACAATGTTTGTGTTGAAAC

>NZ_CP006999|1|1|656030-656257|CRT
GTTTGCTAATGACAATGTTTGTGTTGAAAC	AGAACTGTTTTAACCTCACTTCCATCAATCTCTTTT
GTTTGCTAATGACAATGTTTGTGTTTAAAC	CAGTATGCCATTTGATTCTAGTTCGCCTATAGCTCT
GTTTGCTAATGACAATGTTTGTGTTGAAAC	CATCCTCCTTTTAATTTATTACATTTAAACAATTTA
GTTTGCTAATGACAATGTTTGTGTTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006999.2\|WP_002849050.1\|653458_654235_+\|indole-3-glycerol-phosphate-synthase-TrpC	unknown	unknown	gnl\|CDD\|234710
NZ_CP006999.2\|WP_024305373.1\|652166_653462_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274350
NZ_CP006999.2\|WP_002849068.1\|657736_657985_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006999.2\|WP_002849077.1\|660541_661258_+\|arginyltransferase	unknown	unknown	gnl\|CDD\|234939
NZ_CP006999.2\|WP_002849074.1\|658866_660312_+\|acetyl-CoA-carboxylase-subunit-A	unknown	unknown	gnl\|CDD\|169452
NZ_CP006999.2\|WP_024305374.1\|649211_651134_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NZ_CP006999.2\|WP_002849052.1\|654234_654741_+\|HIT-domain-containing-protein	unknown	unknown	gnl\|CDD\|238606
NZ_CP006999.2\|WP_046037358.1\|664011_665493_+\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|223383
NZ_CP006999.2\|WP_002849076.1\|660318_660555_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006999.2\|WP_010403934.1\|651130_651826_+\|methyltransferase	unknown	unknown	gnl\|CDD\|226608
NZ_CP006999.2\|WP_002849044.1\|648248_649202_+\|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|379355
NZ_CP006999.2\|WP_025370330.1\|656267_657035_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|213641
NZ_CP006999.2\|WP_002849067.1\|657010_657328_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006999.2\|WP_011731910.1\|661314_662139_+\|adenylosuccinate-lyase	unknown	unknown	gnl\|CDD\|236352
NZ_CP006999.2\|WP_011731911.1\|662183_662957_+\|pyridoxine-5'-phosphate-synthase	unknown	unknown	gnl\|CDD\|235380
NZ_CP006999.2\|WP_011731891.1\|654737_655475_+\|YaaA-family-protein	unknown	unknown	gnl\|CDD\|377151
NZ_CP006999.2\|WP_002849039.1\|645441_646785_+\|3-deoxy-7-phosphoheptulonate-synthase-class-II	unknown	unknown	gnl\|CDD\|366662
NZ_CP006999.2\|WP_002849042.1\|646946_648170_-\|glutamate-5-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143398
NZ_CP006999.2\|WP_002849046.1\|651819_652191_+\|YkgJ-family-cysteine-cluster-protein	unknown	unknown	gnl\|CDD\|223799
NZ_CP006999.2\|WP_002849081.1\|662953_663877_+\|4-hydroxythreonine-4-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|179681

Protein	Function_ID	Function_description	E-value
NZ_CP006999.2\|WP_002849050.1\|653458_654235_+\|indole-3-glycerol-phosphate-synthase-TrpC	gnl\|CDD\|234710	PRK00278, trpC, indole-3-glycerol phosphate synthase TrpC.	6.08927e-122
NZ_CP006999.2\|WP_024305373.1\|652166_653462_+\|hypothetical-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	9.35572e-08
NZ_CP006999.2\|WP_002849077.1\|660541_661258_+\|arginyltransferase	gnl\|CDD\|234939	PRK01305, PRK01305, arginyl-tRNA-protein transferase; Provisional.	7.00248e-89
NZ_CP006999.2\|WP_002849074.1\|658866_660312_+\|acetyl-CoA-carboxylase-subunit-A	gnl\|CDD\|169452	PRK08463, PRK08463, acetyl-CoA carboxylase subunit A; Validated.	0
NZ_CP006999.2\|WP_024305374.1\|649211_651134_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	9.18393e-08
NZ_CP006999.2\|WP_002849052.1\|654234_654741_+\|HIT-domain-containing-protein	gnl\|CDD\|238606	cd01275, FHIT, FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into three branches: the Hint branch, which consists of adenosine 5' -monophosphoramide hydrolases, the Fhit branch, that consists of diadenosine polyphosphate hydrolases, and the GalT branch consisting of specific nucloside monophosphate transferases. Fhit plays a very important role in the development of tumours. Infact, Fhit deletions are among the earliest and most frequent genetic alterations in the development of tumours.	3.923e-47
NZ_CP006999.2\|WP_010403934.1\|651130_651826_+\|methyltransferase	gnl\|CDD\|226608	COG4123, COG4123, Predicted O-methyltransferase [General function prediction only].	5.72991e-53
NZ_CP006999.2\|WP_002849044.1\|648248_649202_+\|NAD(P)-binding-domain-containing-protein	gnl\|CDD\|379355	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase.	1.83609e-57
NZ_CP006999.2\|WP_025370330.1\|656267_657035_+\|hypothetical-protein	gnl\|CDD\|213641	TIGR01641, Uncharacterized_protein_MJ0329, phage putative head morphogenesis protein, SPP1 gp7 family. This model describes a region of about 110 amino acids found exclusively in phage-related proteins, internally or toward the C-terminus. One member, gp7 of phage SPP1, appears involved in head morphogenesis. [Mobile and extrachromosomal element functions, Prophage functions].	0.000442902
NZ_CP006999.2\|WP_046037358.1\|664011_665493_+\|inorganic-phosphate-transporter	gnl\|CDD\|223383	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism].	1.16118e-49
NZ_CP006999.2\|WP_011731910.1\|661314_662139_+\|adenylosuccinate-lyase	gnl\|CDD\|236352	PRK08937, PRK08937, adenylosuccinate lyase; Provisional.	2.29446e-18
NZ_CP006999.2\|WP_011731911.1\|662183_662957_+\|pyridoxine-5'-phosphate-synthase	gnl\|CDD\|235380	PRK05265, PRK05265, pyridoxine 5'-phosphate synthase; Provisional.	9.13382e-114
NZ_CP006999.2\|WP_011731891.1\|654737_655475_+\|YaaA-family-protein	gnl\|CDD\|377151	pfam03883, H2O2_YaaD, Peroxide stress protein YaaA. YaaA is a key element of the stress response to H2O2. It acts by reducing the level of intracellular iron levels after peroxide stress, thereby attenuating the Fenton reaction and the DNA damage that this would cause. The molecular mechanism of action is not known.	3.02596e-45
NZ_CP006999.2\|WP_002849039.1\|645441_646785_+\|3-deoxy-7-phosphoheptulonate-synthase-class-II	gnl\|CDD\|366662	pfam01474, DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyze the first step of the shikimate pathway.	0
NZ_CP006999.2\|WP_002849042.1\|646946_648170_-\|glutamate-5-semialdehyde-dehydrogenase	gnl\|CDD\|143398	cd07079, ALDH_F18-19_ProA-GPR, Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19. Gamma-glutamyl phosphate reductase (GPR), a L-proline biosynthetic pathway (PBP) enzyme that catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The glutamate route of the PBP involves two enzymatic steps catalyzed by gamma-glutamyl kinase (GK, EC 2.7.2.11) and GPR (EC 1.2.1.41). These enzymes are fused into the bifunctional enzyme, ProA or delta(1)-pyrroline-5-carboxylate synthetase (P5CS) in plants and animals, whereas they are separate enzymes in bacteria and yeast. In humans, the P5CS (ALDH18A1), an inner mitochondrial membrane enzyme, is essential to the de novo synthesis of the amino acids proline and arginine. Tomato (Lycopersicon esculentum) has both the prokaryotic-like polycistronic operons encoding GK and GPR (PRO1, ALDH19) and the full-length, bifunctional P5CS (PRO2, ALDH18B1).	0
NZ_CP006999.2\|WP_002849046.1\|651819_652191_+\|YkgJ-family-cysteine-cluster-protein	gnl\|CDD\|223799	COG0727, COG0727, Predicted Fe-S-cluster oxidoreductase [General function prediction only].	1.65843e-13
NZ_CP006999.2\|WP_002849081.1\|662953_663877_+\|4-hydroxythreonine-4-phosphate-dehydrogenase	gnl\|CDD\|179681	PRK03946, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Provisional.	0

>NZ_CP006999.2|WP_011731891.1|654737_655475_+|YaaA-family-protein
MKILFSPSESKMSGGSRDASVNFSWVFPNLNDKRLEILEMYNSFLKKANKNELQALFGLKKDNELEYYSSDLFSRPLMKAILRYNGVAYEHLNYRNLDERSRKMIDENTIIFSNLYGVILAKDMIFDYKLKQGESIGGFRTEVFYKKYFSGVLDDFLDSDILDLRAGFYEKFYSLTKPYTTIKFLKNGKVVSHFAKAYRGIVLRCIALNQISSLDEFYNMQIPNLKINKIIKNRLKTEIVVDIIG
>NZ_CP006999.2|WP_002849052.1|654234_654741_+|HIT-domain-containing-protein
MEHEFSPWRAEYFKTRKDDGVTDHSCVFCDIAENIQNDEENFVLFRAKNCFAVMNRYPYTLGEFMIIPYIHTDNIENLDKNIWSEMSDLVQLGVGVLKESLNANGVNIGMNLGSAAGAGIAEHIHYHLVPRWSRDTNFITTIAYTRVHGVPFLDQYHTLKKAFQKIFK
>NZ_CP006999.2|WP_002849050.1|653458_654235_+|indole-3-glycerol-phosphate-synthase-TrpC
MILDEIISKTKINLENIKENLPLCRLENALTNSYIPRDVKQVLKQKNSINIIAEIKKASPSKGVIKEDFDPLKIAFEYEKAGVSAFSILTEPFYFQGSLEYIALVRRYTNTPILRKDFIVDIYQIAEARLYGADFILLIAKALDKFYLKTLFEYAKSLNLEVLMEIHDETDLEKALFVDADIIGINHRNLQTFDMDMELCIKLIPLIPSGKIIVAESGLYNNSELINLKKQGADAFLIGEHFMRQESIYNAVKDMKGE
>NZ_CP006999.2|WP_024305373.1|652166_653462_+|hypothetical-protein
MYWCRAALIFTLFLAGCADKQSVGAKKNETFFKYSDINTTIDLEAMKGFYLLGDAKSKDALEVFYMLYKTTKKPIFLKEALKIAFVIKDDRLDELITDAREILNADYDVIRIEIGYYILKSQIKDAKDLALNLIQKESDNSINHSILATIYLFNDEPIRALKEFKKAYEIEGSEENLLKLVDMLDNKLDRTNEAIRYLNNWIGENGCSKPVCFTLLNIYSAKGELDLMIEVYIKLYEAYEESDFLNRALEILLYKKDVISAKELLEKYSFNEPILMEIYAELKEFQKAYNVAQDLYNRSQNPEYMARMAIYKYEQSSKNISKFELDMVVKLFEGSVYALNSPIYFNYYGYLLIDYEIDLKKGLDIAKKAYILDPNSPYIIDSIAWGYFKLGECKEAKMWMDKIQSDTKFMKEDEAKAHKTAIDKCFNKGTK
>NZ_CP006999.2|WP_002849046.1|651819_652191_+|YkgJ-family-cysteine-cluster-protein
MLKEFGFDYCFDSSKCEVCGAKCCTGDSGYIWISEAEMESLSSHLKLSLPEFKKLFTYRVGVRFSLKEKEYNGAYACLFFDENNKNCSVYEFRPKQCRTFPFWDYFKKHFNELEKECIGVERL
>NZ_CP006999.2|WP_010403934.1|651130_651826_+|methyltransferase
MKLFQLKEGYRYNSDTLFLYDFISKNQIFGNVLDVGCGCGILGLLLKRDFINLNLSSIDIQEINSTITQLNADVNNLVAAVICDDFSKFKSEIKFDFIVSNPPFYNSQITKSENEHISISRYSSSLDPLSFFKSVNANLKPQGVLYFCYDARRVGEILPILSSLKLKLTKLRFVHSRISESSKLALFEAKKSSKSICGIYPPLIIFDENEFSGEVKEIFKKSDTKSEIYEC
>NZ_CP006999.2|WP_024305374.1|649211_651134_+|hypothetical-protein
MKFRKFAQILFLVGTIFFILGCETKDEKALNQDKLKFSDLSMAEQDRYISKDELDKLGSYLTLLNNRNIDINSDEIPSGSVDELRDKIAELIQKNRLLFADNEELAKKNLEIITKLREQNSLRESENKLISAKYLDSMNEVEKQHYKNINDLTKKINEVQKENIQSIKSYEQKIIGLENKIDELEKELSKKDINFNEKVSSATKDQLEKNKELSQKNSYLLEQTQVLKKQVDTLSKELDSKLADKKTQIDTLNQTILTKDNKINDLLASHTNEIIELQNKHSKALYDIKNELDRQKNDYFGELNLKNSELAKLNNDFKEYKLKKDEELKNAENRVLINYKKIETQRLNAIKSDYERIIFEQNRTIAAFEGKMINLELKFKKDLEAKDANYVNTLENLKQKALFLKNDEDRLRAEFDKNITSLKSQITLKNIQISELDSKIKELENEKNDIKKIQNYEILNNMITKLNAQNEELKNYAKKALDEAKKMVLEAENKAKEQNDKLKNYYEELIKNIKNQDNQPVLSDINVDSKRFLSEISCLSLDKSAKLDKDCENKLNDMIKKYGKSRIYEIKAVISDFKFLGDDKVGELKNVNLLNLKSTKDMLNAASKAINSKIKDPMLAYSKDVLLEQSGYGFVIKVYE
>NZ_CP006999.2|WP_002849044.1|648248_649202_+|NAD(P)-binding-domain-containing-protein
MENIYDVVVIGGGPFGIATVVEAKYNGFKNVLLLEKGDNHSQTIRKFYKDGKRVDKVYKGLDSQTHGNVEFFDGTKESTLNYFDNLLDNGKIDAVFNIEVESVKKDGDIFNIVTSKNTYKSKNVMIGIGRMGKPNKPEYKIPPSLTQIVNFNLNSCNCGENILVIGGGNSAAEYAIELSKCNTVTLCYRKEKFTRLNEINEAQVFEYFNDKKLNLKLGIDVIGLDNENGKVKVNFSNNSSEIYDRIIYAIGGSTPVDFLQKCGIELNKDGEPIVDEHLQTNTPRLFVGGDIASKNGGSIVVALNDAHTVIDYIIKSK
>NZ_CP006999.2|WP_002849042.1|646946_648170_-|glutamate-5-semialdehyde-dehydrogenase
MEKLLNNLKNSSKSLSILTQTQRENLIINIANEIMSAKDEILSANKIDLDLAQDLSSALKDRLKLTSKSIENLCNSIKNIANLKDVIGVIKDGWQTKSGLKIEKITIPLGNIATIYESRPNVTAEVAALCIKSANGCALKGGKEAKNTNLAIIKAIHKALQKCGLDKNCVVYLDIDRNEVKKLINMDKYLDLIVPRGGENLVKFVSQNATIPVLKHDKGLCHIYVDEFADLDKALSICVNAKCSRPGVCNAAETILVHEEVANEFIPNLKKSLDEFNVIIFGCKKTAKIIDCELANEQNYSTEYLDFKLNLKIVKNLEESLEHISEFSSGHSEAVISESYSICERFLSLVDSACVYANASTRFSDGGEFGFGAEIGISTNKLHARGPVGLNELTTYKYIIRANGQIR
>NZ_CP006999.2|WP_002849039.1|645441_646785_+|3-deoxy-7-phosphoheptulonate-synthase-class-II
MSKWNRDSWRDYNILQQPHYPDKNELKNAEDKLKSLPPLVFAGEVRNLKDELKNVTLGKSFLLQGGDCAESFSNFSANGIRDMFKIMLQMAIVLTFAGGCPVVKVGRVAGQFAKPRSSDFEDIDGVKLPSYRGDIINGFDFTEEARIPDPKRMIDAYYQSASTLNLLRAFSRGGLANLNEVHRWNLGFIKKAELDNKFEKLADELTGALKFMEACGVTTQNTPTLSETKLYTSHEALLLPYEEALTRVDSLTNEWYDCSAHMLWIGERTRGINDAHVHFLSGIKNPIGCKIGPDGKPGDIISLAGKLNPDNEPGRLNIIIRMGADKIEDRLPAILNYVKKEGLNILWSIDPMHGNTIKASSGFKTREFNNVMREVKSFFEIHRACGTIAGGVHLEMTGQDVTECVGGAFNVTEDSLGNRYETQCDPRLNADQALELAFLIADLVKKR
>NZ_CP006999.2|WP_025370330.1|656267_657035_+|hypothetical-protein
MAETLKEKFKGVLSANTSYFEGVSDHIISQAQNIARVNQSSKYGVKHYKVLARIDSRTSDICRSMNGRIIPASHIEAQSNNIQNAKDINEKKAAAIWRNEPFLGKILPSNFGLPPYHFRCRTELVPVWINEEEIDGVKMKNTSPLSKDEVVKHIDKTGVERYANKKTFNHSISSNKRKISSSDSVKALNSILKIAPHKDYQNRSVAISQNGYFMIFNGDYLYNIFKPSRNLEKYFKDSAVLNKVEIIKWKFSIFA
>NZ_CP006999.2|WP_002849067.1|657010_657328_+|hypothetical-protein
MEIFNICLAHGWAIESVKNGNFGENAKYDLFAQFDVFYGQIAWIYDICTPSDETIKECEKIAIFKQMCEFNVYISDDNDEGWTKKVNFTGTFIDALEYIKANFGK
>NZ_CP006999.2|WP_002849068.1|657736_657985_-|hypothetical-protein
MAWTRSGHPVSGALVGGGGRTGSRTAKAFAKQVNHPGTKAQPYLEDGLNNYISSSGLAMAKEDLAKDVRNKVLNDIKKALKL
>NZ_CP006999.2|WP_002849074.1|658866_660312_+|acetyl-CoA-carboxylase-subunit-A
MIHKILIANRGEIAVRIVRACKDLHIKNVAIYTEPDRECLHVKVADEAYQIGKDPIKGYLDSKRIVEVAKACGADAIHPGYGFLSENYEFSKEVEDAGLIFIGPNSDIIRKMGNKNIARFLMKKNGIPVVPGTEKLNSETIEAIKNYAVRIGYPVILKASGGGGGRGIRVVWKEDELESSYESCKREAKAFFNNDEVFMEKYIEKPRHIEFQILGDNYGNLIHLCERDCSIQRRHQKVIEIAPCPTISEDLRKRMGVAAVAAAKAVGYTNAGTIEFLLDDYNNFYFMEMNTRIQVEHGVTEEITGVDLISRQIRIAAGEILDIEQNEVRPQGVSIEARITAENVWKNFAPSPGRITGYFPALGPGVRVDSHMYQDYVIPPFYDSLVAKLIVKGTSYDLAVSKLERALDEFKIEGVRTTLPFLLAISKRRHFRRGFFDTSYIEERLQDILENTQDHHQENKEEVIAAIAAAIKKVKEDRAKE
>NZ_CP006999.2|WP_002849076.1|660318_660555_+|hypothetical-protein
MNDFFDSLKNIKNELVKEQKSQEIKVPKKPKPNPNRDEFKDIFAEPNEIEMPDAKEHRLKDEFLEFIKHSDVKKLERD
>NZ_CP006999.2|WP_002849077.1|660541_661258_+|arginyltransferase
MREIDFCTLDTLCPYLEDRNSRTMYRYVSQCSFDYNSNLVKHGYRRFGSYFSKPICDGCDECKSIRIDAFNFKFTKSHRRIINKNSNTKIVVSKPYISQRHIDLYEKYHKFMHEKRGWEYYNLDFRRYYSVYVEGAGDFGYEIDYFVNDELVCVDLVDIVDDGISSIYCYWDIDFAHLSLGKFSLLNQITIALKNDLRWIYLGFYVKDCASLAYKGEYKPYETLKTYCDIDEKPIWEF
>NZ_CP006999.2|WP_011731910.1|661314_662139_+|adenylosuccinate-lyase
MQITQTLESITITTDDCDLFLNLSNKIRQSFANAIGNRDKVIIFYNENELVQRKYFLKLIGKIYANSVGKGIDFLLTHHKNIKLVYKKPNSLQILINVDVKFENSRVVLDLKNSEELFTKYLIRGLGDTRHEYFESKNILVISPKTTEDVELLDNILNFREHLKYIVNFNYDKKAYDEFKKRAKILTSKAYIRRFSMLANLLEEHFETLGCKATDDFETVRTNYLNLTKVYHPDKHAGKPNEVQKSYIDKFQKIGLAYEALKPYFKEQKSFISA
>NZ_CP006999.2|WP_011731911.1|662183_662957_+|pyridoxine-5'-phosphate-synthase
MKLGVNIDHVAVLREARAVNDPQIIHAMFEAVSGGADQITIHLREDRRHINEDDVKNIINLSPIPVNLECSINSEIIDIVCELKPHRATIVPEKREELTTEGGLSLDSLNLKNVISKLNDNDIKVSLFINPKKNDVIMSKELGATCVELHTGAYANTFLMLNSNLNHTKYKIDNLNLKRGELEILLNSELTRIKEAANISTNLGLEVAAGHGLNYQNVTAISSIKDIFELNIGQSIVAKSVFVGLKNAVKEMMELVK
>NZ_CP006999.2|WP_002849081.1|662953_663877_+|4-hydroxythreonine-4-phosphate-dehydrogenase
MSLPKIAISVGDINGVGIEIALKSHDEIKNICSPIYFINNELLNSAANILKFTVPNDFEIFECGSSFNIKPGRVSKKSGKFSFVSFENAILYTQNKRAQALVTMPINKESWKKAGVPYVGHTDALGKYFGKNAIMMLGCEELFVALYTDHLALKDVSAKIKAKNLALFLVDFYNSSKFENIGVLGFNPHASDNETIGGKEEKEIIKAIKSANNRLKKEVFTGPLVSDAAFTKSSLKRCNRLVSMYHDVGLAPLKALYFDKSINVSLNLPIVRTSVDHGTAFDIAYKGKAETKSYIEAIKFAIKLCDY
>NZ_CP006999.2|WP_046037358.1|664011_665493_+|inorganic-phosphate-transporter
MWGYNYIPSNHLLLFILASIFGLFMAFNIGGNDVANSFGTSVGAKTLTLKQALIIAAVFELSGAVFAGAEVTNTIRSGIVSLPRGDVNPMVFVIIMISALFSSGAWLFIATKKGLPVSTTHSIVGGIVGAGMMMGFIYYNGSKTFDMVQWGEIGRIALSWVISPVMGGVMAYLIFGYIKSKIIIPSSRIQSEIKSLKRARKTYKDQYIKELSNKSEAEQIKELRRIAIIDEDECEGENCDFRDKIKAMKEQEKNIDGMVFMRTHIPMVAGVAAMIIAGSMLFKGLKHMDFNLSIIQTIWIIFVIGIAAYLASFAIVNLMKKDNPQKGINRIFGWFQIFTASSFAFSHGANDIANAVGPFAAILDVLKNNTINETTPIPGIAMATFGIALVVGLWFLGKEVIATVGTKLAEILPTTGFSAELAASIVILIATKMGLPISSTHVLIGAVLGIGVYNRNANWGMLKPIGLAWIITLPISMIGSAIGFLVIKNIMGL

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Crispr_ID: NZ_CP006999_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006999_2

1802843-1802977

Orphan

Consensus_repeat	Method
ATTTTATCATTTATGATGATCTAGGAAATAATATAGAAAATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006999_2

>merge|NZ_CP006999|2|1802843-1802977|CRISPRCasFinder
ATTTTATCATTTATGATGATCTAGGAAATAATATAGAAAATATTGAAAAAGAAATAGTTGATAACAAAAGAAATTTTTTTAGTTTTAATGATGATTTTATCATTTATGATGATCTAGGAAATAATATAGAAAATA

>NZ_CP006999|2|2|1802843-1802977|CRISPRCasFinder
ATTTTATCATTTATGATGATCTAGGAAATAATATAGAAAATA	TTGAAAAAGAAATAGTTGATAACAAAAGAAATTTTTTTAGTTTTAATGATG
ATTTTATCATTTATGATGATCTAGGAAATAATATAGAAAATA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006999.2\|WP_002847781.1\|1811515_1812262_+\|HugZ-family-heme-oxygenase	unknown	unknown	gnl\|CDD\|200360
NZ_CP006999.2\|WP_002850911.1\|1797840_1798668_+\|DUF1738-domain-containing-protein	unknown	unknown	gnl\|CDD\|377992
NZ_CP006999.2\|WP_002850907.1\|1795497_1797417_+\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	unknown	unknown	gnl\|CDD\|226036
NZ_CP006999.2\|WP_024305357.1\|1808015_1808582_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006999.2\|WP_002850920.1\|1800839_1802780_+\|type-IA-DNA-topoisomerase	unknown	unknown	gnl\|CDD\|223624
NZ_CP006999.2\|WP_002850900.1\|1794129_1795074_+\|Flp-pilus-assembly-complex-ATPase-component-TadA	unknown	unknown	gnl\|CDD\|274301
NZ_CP006999.2\|WP_024305491.1\|1806382_1806661_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006999.2\|WP_002850914.1\|1798728_1799004_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006999.2\|WP_025370408.1\|1805337_1806336_+\|restriction-endonuclease-EcoRI-subunit-M	unknown	unknown	gnl\|CDD\|372662
NZ_CP006999.2\|WP_002847783.1\|1812543_1814538_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NZ_CP006999.2\|WP_002850918.1\|1800270_1800858_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379235
NZ_CP006999.2\|WP_002850902.1\|1795070_1795505_+\|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl\|CDD\|368576
NZ_CP006999.2\|WP_002850898.1\|1792684_1793893_+\|TrbI/VirB10-family-protein	unknown	unknown	gnl\|CDD\|319755
NZ_CP006999.2\|WP_158004709.1\|1808669_1808822_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006999.2\|WP_002850916.1\|1799052_1800252_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377390
NZ_CP006999.2\|WP_024305358.1\|1809870_1811418_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|236707
NZ_CP006999.2\|WP_011732334.1\|1812261_1812456_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006999.2\|WP_025370409.1\|1807131_1807779_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|222854
NZ_CP006999.2\|WP_024305372.1\|1793906_1794128_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006999.2\|WP_002847774.1\|1809015_1809819_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444

Protein	Function_ID	Function_description	E-value
NZ_CP006999.2\|WP_002850911.1\|1797840_1798668_+\|DUF1738-domain-containing-protein	gnl\|CDD\|377992	pfam08401, DUF1738, Domain of unknown function (DUF1738). This region is found in a number of bacterial hypothetical proteins. Some members are annotated as being similar to replication primases, and in fact this region is often found together with the Toprim domain (pfam01751).	0.00766572
NZ_CP006999.2\|WP_002850907.1\|1795497_1797417_+\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	gnl\|CDD\|226036	COG3505, VirD4, Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion].	1.18638e-62
NZ_CP006999.2\|WP_002847774.1\|1809015_1809819_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	6.29496e-13
NZ_CP006999.2\|WP_002850920.1\|1800839_1802780_+\|type-IA-DNA-topoisomerase	gnl\|CDD\|223624	COG0550, TopA, Topoisomerase IA [DNA replication, recombination, and repair].	1.1352e-137
NZ_CP006999.2\|WP_002850900.1\|1794129_1795074_+\|Flp-pilus-assembly-complex-ATPase-component-TadA	gnl\|CDD\|274301	TIGR02788, conjugal_transfer_protein, P-type DNA transfer ATPase VirB11. The VirB11 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for DNA transfer. VirB11 is believed to be an ATPase. VirB11 is a homolog of the P-like conjugation system TrbB protein and the Flp pilus sytem protein TadA.	1.26229e-53
NZ_CP006999.2\|WP_002847781.1\|1811515_1812262_+\|HugZ-family-heme-oxygenase	gnl\|CDD\|200360	TIGR04109, heme_ox_HugZ, heme oxygenase, HugZ family. Members of this protein family are HugZ, a class of heme oxygenase that belongs to the PPOX family (pfam01243) and lacks homology to the HmuO family (pfam01126). Characterized members of this family include HP0318 from Helicobacter pylori and CJ1613c from Campylobacter jejuni. This enzyme releases iron during the conversion of heme to biliverdin.	3.38351e-122
NZ_CP006999.2\|WP_002850918.1\|1800270_1800858_+\|AAA-family-ATPase	gnl\|CDD\|379235	pfam13521, AAA_28, AAA domain.	1.73817e-08
NZ_CP006999.2\|WP_025370408.1\|1805337_1806336_+\|restriction-endonuclease-EcoRI-subunit-M	gnl\|CDD\|372662	pfam13651, EcoRI_methylase, Adenine-specific methyltransferase EcoRI. This methylase recognizes the double-stranded sequence GAATTC, causes specific methylation on A-3 on both strands, and protects the DNA from cleavage by the EcoRI endonuclease.	1.42983e-88
NZ_CP006999.2\|WP_002850902.1\|1795070_1795505_+\|plasmid-mobilization-relaxosome-protein-MobC	gnl\|CDD\|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	0.00151096
NZ_CP006999.2\|WP_002850898.1\|1792684_1793893_+\|TrbI/VirB10-family-protein	gnl\|CDD\|319755	cd16429, VirB10, VirB10 forms part of core complex in Type IV secretion system (T4SS). This family contains VirB10, a component of the type IV secretion system (T4SS), including homologs TrbI, TraF, TrwE and TraL. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both, the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TrwE in R33 plasmid has been shown to be anchored to the inner membrane and its C-terminal is necessary for conjugation; the transmembrane domains of TrwB and TrwE are involved in TrwB-TrwE interactions. TraF protein of the RP4 plasmid is involved in circularization of pilin subunits of P-type pili. In gonococcal genetic island (GGI) of Neisseria gonorrhoeae, T4SS encodes TrbI and circularization occurs via a covalent intermediate between the C terminus of putative pilin protein TraA and TrbI.	1.13063e-59
NZ_CP006999.2\|WP_002850916.1\|1799052_1800252_+\|hypothetical-protein	gnl\|CDD\|377390	pfam04610, TrbL, TrbL/VirB6 plasmid conjugal transfer protein.	0.000267097
NZ_CP006999.2\|WP_024305358.1\|1809870_1811418_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|236707	PRK10522, PRK10522, multidrug transporter membrane component/ATP-binding component; Provisional.	2.79407e-165
NZ_CP006999.2\|WP_002847783.1\|1812543_1814538_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	3.40843e-53
NZ_CP006999.2\|WP_025370409.1\|1807131_1807779_+\|AAA-family-ATPase	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	5.42471e-39

>NZ_CP006999.2|WP_002850920.1|1800839_1802780_+|type-IA-DNA-topoisomerase
MQNTIIIIESPNKCDKIEHITGAKVYATKGHFKELTNQIVADYQSYEPIFDFKGESKSRINAMFNDCKGKDVIIATDPDREGYGIGYMVYDTIKNIAKSVKRAEFHEITESGIKKGLESAVPFASSNLKEFDSFKARAVGDKLVGFIMSPTYINKLNDKNISVGRVQTPALALIVKRELEIKAFNENKANAKIDYKIKAKLRTRDGIEFNALNDNIFVSKDEANAKISDLNGFNAKVYQIDTKETQIKPKLPFRTSQLQEIANKKLLFSPDKTMSIAQKLFEKGLITYHRTDSNSLSNEFIDEVGAKFGDEEWYEKREYKAGAQSQAEAHEAIRITHVHNFISIDEMALTDDDKRLYELIYLNSIQSQAKNAINENTIYDIDIKTLSFKTKTSKCIYKGFKGALKEEIEDDEDKDKEILEISLNLKQGDEVELMGFELQEVKKQPPQHYKESNFISLLEKEGIGRPSTYATFLPTLLKREYVTIETKGKNNNIVATNKGIKFIENIKQDDDWITQSEFTKQMESVLDEISSGKVSYLDFIKPLHEKMGFKELNNSQTNPPSEKQLEWAKNIAQNLKISLPNGIENSWKICSDFIEKNKDKVVTPPTDKQIELAKKLSKDKGMALPKDYDTNLKICKEFIDKAIKKK
>NZ_CP006999.2|WP_002850918.1|1800270_1800858_+|AAA-family-ATPase
MNKLVINIYGSPGAGKSTLAKNLKKYMREKRIDVGLISEFATELIENNQKEKLKDQPYVTKGQMLNITRVLKKHDIAISDSPIELGKFYCDPRDEQRTNELIKKCKNMYKSINFFLKLDEQAKQDYTMERRVHTYAQSKKLQEEMLSSLILNDKTSIIIYRSTPIKEIFKMIEKSKQWNKHQNQNKGLELCKTQS
>NZ_CP006999.2|WP_002850916.1|1799052_1800252_+|hypothetical-protein
MAQTQVAKDLLTDSNWINKTQNIIQENVMSLFEKFYQGAHDLVYSTATTTIVILIVSLWLLNRLKNGYPTRNEIFVAVKYIIQLCFIFAILSSFDAYQGVLYALTIPENVIITILSSIFEGRDFGAIVTESANRVDNIRALMWNYGTTEYLKTQAWSFLGISFNGVMDYLGAGIITALSMIPFWIFYIVFFLLLVGITIVIFFSKFMAFLILSTLPLVIPFLIIPRFLPYLWSWYKLYLSYAIIAPLAFIALNLAINPILELENYQNYISELFVKQFEYLITGSITCISALFLLKKIPSWINAVLGTQMESGSGGVVGGVVAGAVASKTLLGGLARKATGGSFVGGALSSLGAASGANVAGQIASASIGAGANVAKDIGRGIGKTYEAYKKFKGGYVAP
>NZ_CP006999.2|WP_002850914.1|1798728_1799004_+|hypothetical-protein
MLNEFLNFLGFNKAVCKKQLHTDNTDIKENVEMQEYIVEMQSPDFKEETTTETVIKDGKKIEIQKIKTTEPLNNGKTLITTKIYKKDITRM
>NZ_CP006999.2|WP_002850911.1|1797840_1798668_+|DUF1738-domain-containing-protein
MEQVRKSWEQMDNAEKKESFDKYMKFKLFEAHKTGKADWQKDMSKEEVDNTMPYNAKTGNTYSRETNMLLRAEMAIKGYDKAQFVTMEQGNAMGGVLKLKHDEQTGEVVKTKNGKDARVDGVKMLYIADHELRPKLDKDGKEVTAVVKDKDGNVKYDQETGQPMTYVVKEKIPIKPRLETKTLYHVSQFDGLDESKIKDRDLTAVTHYREQSKNQDFEVKISYGKTLGISGNLEKQLDNLTLAQIKGVDYYNPAVKVEMTKQKAQTKEQNKGMER
>NZ_CP006999.2|WP_002850907.1|1795497_1797417_+|type-IV-secretory-system-conjugative-DNA-transfer-family-protein
MDDTQKFSTKKWIIIFISSLIMGVLAYLAMVKVIFNPDLVNVPAVAIKILNNIGSPMLKLKAYVALFALVAPFLVVVAWWLMPYFSDNENYGSARFATPDDFKKMSINYKNGLVLGCLNIDSENPKFLRATRPLATLVVAPPGSGKTAGMIIPNLLSIPNSSVTLDIKGELYQKTAGYRQKYFKNEIQLFSPFSWDNTLFFNPFDYSIVKDMEYIRIKKLADQIANTIFVAEKEKENDHWVLSAKTLFVFFAEYFMQKNKHTTLGELAQAPKADYFDYLDEKFGEEAMKEIDEDNPEAPRERDYDVDTFKIWLKQTANDTSIDESTRNQARAYAKAAENEFASIKSTYDTFMKVFSHPQVASATSKMSFAFEDLREKRISMYVVIQTEDMEILAPLIRIFIETLFKKLMSGKENSDPDKFIYCFLDEFVRFGKMPFLLEAPALCRSYGLLPVFVTQAYEQIKKYYGEDDMNIVKNNSGYHVIFGMNSEKDAKDTSELIGDYTNIKISKSQGNMDLFKSNISKSKEAKRLVTAQDLKNQDSNDIYILVSKFFKMPIKAKVPYWFKIVQFKGANEIEVKAIAQKEQTNTHKPQDTNILQNSPATAQQNSQKTNESKVEVADMDKQQRDELLKALKIKVDRE
>NZ_CP006999.2|WP_002850902.1|1795070_1795505_+|plasmid-mobilization-relaxosome-protein-MobC
MKKTRHHIYLTEADDRILRKLSDKQNQSRSAIVRKLLQTQKYKDNLKEIETNNRIIGGYLKEFSHIGTNINQIAYHLNANITDHEEAKTDFEKNIVKLMQIIKELNEKIDTLKIKINVPHIKTPSNIKERDRMEEYEIKRKENG
>NZ_CP006999.2|WP_002850900.1|1794129_1795074_+|Flp-pilus-assembly-complex-ATPase-component-TadA
MAESIILNNILGVLKPYLNLNANELIFNKPCEINIDYGDHWEIVQDPKLDARFLNSFLVELATRRNQRFDESHCHLSCELPSPFLRYRVQAQHKSSLFNSEIAICIRIPSKEIYPLESFILSDKCIKDGWNYDKIKELIHKKKNVLLSGGTGSGKTSFLNSLMGEIDPNERVVTIEDSQELRVENINKTQLAVPKIATEIYSYQVAIDNAMRLRPDRLFLGEIDIRNTFSFLRVNNTGHAGNLSTLHANSPRDAIKAIKTNVILGGGLSNVDDGMIDSLIITAIDYIIQITRVKNKRVVTDILNLKEDMGKIVA
>NZ_CP006999.2|WP_024305372.1|1793906_1794128_+|hypothetical-protein
MEYEIIKEQINAELQNKKTNDKLLEKIAIQLKKIEKAETVYLKEKAKLENLVAQKQNLSNGVTTKQVEQDKEE
>NZ_CP006999.2|WP_002850898.1|1792684_1793893_+|TrbI/VirB10-family-protein
MKKGNKKLFLSLATISILSTPLFANNQEAVLNLDNGNKSKLDRQIRNLQNQADLSHLFENSKFPVDDYIYKAGKREPNQDQNLTQILKDFEKLDQKQKAQAADKNLIQPSQYAEQEQEEMTQHIKQKQEELQAQQEQLRQEITMDSQKAYKKRMQELIRAQILANRNNEVKSVNQNSSKFGVDGFSNQKSIDISTNEHRLYRTIRAGRMIPAILTTAISSDLSGIVTAQIEQDIYASMGRAVLIPRGSKAIGFYTNNTKIGHERLEIRWREIITPQGINIMLTDALVADNMGMAGAIGAINNKYWERYGIAYSISTITNGIMLGIASKMNTNGSANNQYATEMYSNAKSDISSIVQDIMQQQSQIKPTIEIRSGSRIFLVPTNHMWFAKPKNGEVLMQYFND
>NZ_CP006999.2|WP_025370408.1|1805337_1806336_+|restriction-endonuclease-EcoRI-subunit-M
MNHKNQLNQETNWMSNKEKKPNIYFMKAKYEIDDEFYTSYHEIKKELDDYKSHFKGKIVVCPCNDSRKSNFYKYFRINFKNLELKKLITTTFNINNVNLKGTKIEITNDSASETQLQGRGDFRSDEVKEIIAQGDIIVTNPPFSLFRDLIDIVESYNKKFLIVGGTYSITYKKIFELYEKGKIWLRNHQVCIFTRPNGTKKRFSNISWFTNLKSIKHLEPIKLTKRYKNNEHKYPEYDNYKVIEVTSYKDIPIDYYGIIGVPLTFFLRHNPAQFNILGCDFQIKEKYPELVKWDYKENNTKSAVLNGQEMFTRIIVQRKSGLMPRIRLQNQL
>NZ_CP006999.2|WP_024305491.1|1806382_1806661_+|hypothetical-protein
MKFEELEFSGLPDNFLCQKVCEIYKITNKELSDKLGIEIEVLNSLQDNDVRLPKSAKVALELMHIIDIWYNTDLIFKERVVKDETKQEIKTI
>NZ_CP006999.2|WP_025370409.1|1807131_1807779_+|AAA-family-ATPase
MIVSICNEKGGSGKSTLATNIAINQSLSKNELPLLIDTDPQKSIATFLNIRNEENNPKVFDFTYKYGENLKEFLQNYNSNKDVIIDTGGRDSREMRIAIALSDMVIIPTIPSQFDVSVLDKMVNIIKMAKEQNEKLVAYIVINRASTNPFLYKKIESLRNFIEEIEQDYIKLSQTIVYERERYKVATQLGLGVVEMKDGNKAEQEIRDLCNEICT
>NZ_CP006999.2|WP_024305357.1|1808015_1808582_+|hypothetical-protein
MNFKKTTNSIENLDAFIDGADTQKDTSIDKKVSVVTKISKELSNKIKLKYPKMPLTKYIEQALMVKIPHINEDILLTICQQAEWFNTSIADFVRYKMGLMEAPEPNELNKNEEKLENKILYVSNDNKKIIKRNAENIGLSLYRYSEIKIKVTYELKDIFTFEELMQFKAEAINYDLELDEYIAMRIRG
>NZ_CP006999.2|WP_158004709.1|1808669_1808822_-|hypothetical-protein
MIEESNKTIEQIARESLHSLEMTFENFAIFGVCSLMIIGIVTALILSSTR
>NZ_CP006999.2|WP_002847774.1|1809015_1809819_-|replication-initiation-protein
MSDFSFYFEKGEFVLEVSKKNFKKSDGSLVFKNKMNSILFPVNFTARDYDIFFTICWFAKQKGYVENRGFIEMPYSEICRFMPSGLNKTRFNDEVKNFRSKVLGQNGAAIYRSVEITKDDEITTVGVFFTDIKIFRNKQSLSFRLNPIALDVLFSTLKFMRIDLNDFVSIRGKFAKTLYRLLHQYDNIKADKDGFKCVNFSRDDFEKFMSTPMTYNVTDLDRFVIKPSISELDESYFKKIIFEKKIADGSKKNVIGYSFKFILKDAS
>NZ_CP006999.2|WP_024305358.1|1809870_1811418_+|ATP-binding-cassette-domain-containing-protein
MLKLKNKNLILSAITLLSVFYSALNLAVLAFINRYLLNITSGEYGLILYFIILLLLFFIASLAFRYTISLASQNYIYDMRLSIIKRILDTDYHHTRQIGRAKLIALLSSDIASITNGFVRIPEILQGGLVAIVSFFYILYLSPILAFSVFIWLGFGAILCLYFIKKLYNLFKQHRKNEDRLYKNYETSIDAHKEFSLNLKRAADFFNLKFRLNVQDMRKNMLSIDFYQSLVSNWVSMMTLGAVGLVIYLSLGFELLDMAGAVTISIIILFLRAPLMMVLFAYPSIIKSKVAAQKIKSLELAAYKEEFDTYKSFDNWQRIELRNISFSYENKLILDNINMRLDRGECLFLIGENGSGKSTLFLILAGLLKPSSGEIYIDDVKIDSSNIQIYKNTISAVFSEFYLFSDIENDAKKWFELLEFRAPNDSQIDPQNLSQGQKKRLALINALLENRNILLLDEWAADQDPHFRAKFYTEILKLFKQQKITVFAISHDDRYFKYADRIYELIDRKLINYLS
>NZ_CP006999.2|WP_002847781.1|1811515_1812262_+|HugZ-family-heme-oxygenase
MDAKRKAIEHMNSDHMDTLIMLCKHFGAVQNPTNVRLDSIDEDGMDIACDQLLVRVAFLKKAEQNGEGFKTAIIDLMSSLDIKEGIAAVSKDMIDFIDSFNSVLISSLNGDHCVCSYAPVVRDNNDFYILISEVSEHFKSIKENSDKISIMFLEDESKAKTVFARKRASFRSKAIFLDDKKESLFSKFESKFKSESAIKMIKNMSDFHIIKIEINKGRFVKGFGAAYDTDGFEIIQRAHGANPHNNKR
>NZ_CP006999.2|WP_011732334.1|1812261_1812456_+|hypothetical-protein
MKNVKPKETGKLFMSYFSLLITVLWVILEKPVCLMRAKNSNLKFDAKFDKFTKYIIFQKQKYKL
>NZ_CP006999.2|WP_002847783.1|1812543_1814538_+|TonB-dependent-receptor
MLKKITICSLSAATLVFGTQIRLDTTVISTSGFETKLKDEVRNVIVITSEDIQNKGYKNVEEILEAEPSISFIDPGFGRTIDMRGQGINSNFSTKIMLNGVALNMLDTSHATVPINTISVDDIEQIEIIPGGGSVLYGNGTSGGVINIITKNQPRDFYTNLSTKFGSYNYKDLNFAVGGMANDDLFLKFNAKKFDEKGYRDGEKNRGYYTSGGATYQINDNQSVMLNSSYYNATTSTLNALSKAQVNSDPKQGGKKTTKDGTRLDLTLDYALKYGDYVDFHIFPYYQKIKQELDDNSGFEDKKYGINLKNRMDYGNGELIYGYEYYINKGLRYRNNQGSRRGVTVKNSINVDLEKKSHSIYVMDNHHFNDWFSISSGYRFEKASYDLDRSSITNIYMPNSTRPMTTVKNIANQPDTNNHAFEITPNLKYSDTGNIYFKFERGFYSASPTQLTNSVRPQGATRGLVYKFNNLKSEIFYTYEIGAKDYFLGSYMSATAFITDKKNEIRNIMEEDHTLWRFINLDKTRRLGIELYASQYMLDNDLSLKQTYSYVDAKITSGEFNNKRIPLAAKHKLVFGADYKVIRNLNVFGDIKYFSDMLDNGYEKINSKTIVDIGAKYSFPKGFLVIAGIKNLFDKRYFTYQDKIKDQYKPANARNYYVEFKYVY

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	NZ_CP034117	Staphylococcus epidermidis strain CDC121 plasmid pSTA482, complete sequence	6189-6222	6	0.824
NZ_CP006999_1	1.6\|656192\|36\|NZ_CP006999\|CRISPRCasFinder,CRT	656192-656227	36	NZ_CP034117	Staphylococcus epidermidis strain CDC121 plasmid pSTA482, complete sequence	6189-6224	7	0.806
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	KJ018209	Shewanella sp. phage 1/4, complete genome	128609-128642	9	0.735
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	NC_001942	Mycoplasma phage MAV1, complete genome	15559-15592	9	0.735
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	AF074945	Mycoplasma arthritidis bacteriophage MAV1, complete genome	15559-15592	9	0.735
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	AF058280	Mycoplasma arthritidis bacteriophage MAV1 attR site	1146-1179	9	0.735
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	NC_047948	Staphylococcus phage phiSA_BS2, complete genome	41835-41868	9	0.735
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MH078572	Staphylococcus phage phiSA_BS1, complete genome	140909-140942	9	0.735
NZ_CP006999_1	1.1\|656060\|34\|NZ_CP006999\|PILER-CR	656060-656093	34	KM262192	Leuconostoc phage Ln-9, complete genome	17921-17954	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MH937466	Streptococcus phage CHPC875, complete genome	27300-27333	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MH937505	Streptococcus phage CHPC1109, complete genome	24998-25031	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MK250021	Prevotella phage Lak-B2, complete genome	180441-180474	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MK250024	Prevotella phage Lak-B5, complete genome	174449-174482	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MK250028	Prevotella phage Lak-B9, complete genome	179332-179365	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MK250023	Prevotella phage Lak-B4, complete genome	180344-180377	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MK250025	Prevotella phage Lak-B6, complete genome	177642-177675	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MK250022	Prevotella phage Lak-B3, complete genome	177657-177690	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MK250027	Prevotella phage Lak-B8, complete genome	180555-180588	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MK250026	Prevotella phage Lak-B7, complete genome	180560-180593	10	0.706
NZ_CP006999_1	1.3\|656192\|34\|NZ_CP006999\|PILER-CR	656192-656225	34	MK250020	Prevotella phage Lak-B1, complete genome	179312-179345	10	0.706
NZ_CP006999_1	1.6\|656192\|36\|NZ_CP006999\|CRISPRCasFinder,CRT	656192-656227	36	KJ018209	Shewanella sp. phage 1/4, complete genome	128607-128642	11	0.694

1. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to NZ_CP034117 (Staphylococcus epidermidis strain CDC121 plasmid pSTA482, complete sequence) position: , mismatch: 6, identity: 0.824

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
aatcctcctttgaattcattacatttaaaacata	Protospacer
 ********** ****.************  **

2. spacer 1.6|656192|36|NZ_CP006999|CRISPRCasFinder,CRT matches to NZ_CP034117 (Staphylococcus epidermidis strain CDC121 plasmid pSTA482, complete sequence) position: , mismatch: 7, identity: 0.806

catcctccttttaatttattacatttaaacaattta	CRISPR spacer
aatcctcctttgaattcattacatttaaaacatatc	Protospacer
 ********** ****.************  ** *

3. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to KJ018209 (Shewanella sp. phage 1/4, complete genome) position: , mismatch: 9, identity: 0.735

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
ggctattattttaattcattacatttaaacactt	Protospacer
 ... *. ********.************** **

4. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to NC_001942 (Mycoplasma phage MAV1, complete genome) position: , mismatch: 9, identity: 0.735

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
aaactaccttttagtttattaaatttaaacagag	Protospacer
 * *. *******.******* *********.

5. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to AF074945 (Mycoplasma arthritidis bacteriophage MAV1, complete genome) position: , mismatch: 9, identity: 0.735

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
aaactaccttttagtttattaaatttaaacagag	Protospacer
 * *. *******.******* *********.

6. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to AF058280 (Mycoplasma arthritidis bacteriophage MAV1 attR site) position: , mismatch: 9, identity: 0.735

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
aaactaccttttagtttattaaatttaaacagag	Protospacer
 * *. *******.******* *********.

7. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to NC_047948 (Staphylococcus phage phiSA_BS2, complete genome) position: , mismatch: 9, identity: 0.735

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
attcctccgttttatttattacattttttttatt	Protospacer
  ****** *** *************   . ***

8. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MH078572 (Staphylococcus phage phiSA_BS1, complete genome) position: , mismatch: 9, identity: 0.735

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
attcctccgttttatttattacattttttttatt	Protospacer
  ****** *** *************   . ***

9. spacer 1.1|656060|34|NZ_CP006999|PILER-CR matches to KM262192 (Leuconostoc phage Ln-9, complete genome) position: , mismatch: 10, identity: 0.706

agaactgttttaacctcacttccatcaatctctt	CRISPR spacer
agaactgttttaatctcacttgcaatagccgaag	Protospacer
*************.******* ** .*..*

10. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MH937466 (Streptococcus phage CHPC875, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
atacgtccttttaatttatcatatttaaactcca	Protospacer
   * **************.*.********  .

11. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MH937505 (Streptococcus phage CHPC1109, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
atacgtccttttaatttattgtatttaaactcca	Protospacer
   * ***************..********  .

12. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MK250021 (Prevotella phage Lak-B2, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
tccgcatcttttaatttattacatttatataaca	Protospacer
. . * .******************** *.**.

13. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MK250024 (Prevotella phage Lak-B5, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
tccgcatcttttaatttattacatttatataaca	Protospacer
. . * .******************** *.**.

14. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MK250028 (Prevotella phage Lak-B9, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
tccgcatcttttaatttattacatttatataaca	Protospacer
. . * .******************** *.**.

15. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MK250023 (Prevotella phage Lak-B4, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
tccgcatcttttaatttattacatttatataaca	Protospacer
. . * .******************** *.**.

16. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MK250025 (Prevotella phage Lak-B6, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
tccgcatcttttaatttattacatttatataaca	Protospacer
. . * .******************** *.**.

17. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MK250022 (Prevotella phage Lak-B3, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
tccgcatcttttaatttattacatttatataaca	Protospacer
. . * .******************** *.**.

18. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MK250027 (Prevotella phage Lak-B8, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
tccgcatcttttaatttattacatttatataaca	Protospacer
. . * .******************** *.**.

19. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MK250026 (Prevotella phage Lak-B7, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
tccgcatcttttaatttattacatttatataaca	Protospacer
. . * .******************** *.**.

20. spacer 1.3|656192|34|NZ_CP006999|PILER-CR matches to MK250020 (Prevotella phage Lak-B1, complete genome) position: , mismatch: 10, identity: 0.706

catcctccttttaatttattacatttaaacaatt	CRISPR spacer
tccgcatcttttaatttattacatttatataaca	Protospacer
. . * .******************** *.**.

21. spacer 1.6|656192|36|NZ_CP006999|CRISPRCasFinder,CRT matches to KJ018209 (Shewanella sp. phage 1/4, complete genome) position: , mismatch: 11, identity: 0.694

catcctccttttaatttattacatttaaacaattta	CRISPR spacer
ggctattattttaattcattacatttaaacacttct	Protospacer
 ... *. ********.************** **.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1428627 : 1439877

Cronobacter_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002850239.1\|1428627_1429629_+	glycosyltransferase family 2 protein	F1C5B0	Cronobacter_phage	4.8e-61	41.5
WP_011732184.1\|1429633_1431151_+	hypothetical protein	F1C5A9	Cronobacter_phage	2.3e-06	24.9
WP_029662383.1\|1431151_1431532_+	GtrA family protein	NA	NA	NA	NA
WP_002850245.1\|1431532_1432525_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	4.6e-56	41.1
WP_002850250.1\|1432587_1436445_-	N-6 DNA methylase	E3T4D5	Cafeteria_roenbergensis_virus	1.3e-10	29.8
WP_002850252.1\|1436523_1436766_-	hypothetical protein	NA	NA	NA	NA
WP_002850254.1\|1436776_1437541_-	DNA ligase	A0A1X9VNU1	Mimivirus	1.7e-34	34.0
WP_002850256.1\|1437591_1438650_-	NAD-dependent epimerase	A0A2K9L4U8	Tupanvirus	7.2e-31	29.1
WP_011732189.1\|1438659_1439877_-	nucleotide sugar dehydrogenase	M1HWZ1	Paramecium_bursaria_Chlorella_virus	1.3e-28	28.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP007000

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

16573 : 58243

Helicobacter_phage(38.46%)

transposase,integrase

attL 13150:13165|attR 32968:32983

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
13150:13165	attL	NA	NA	NA	NA
WP_025370433.1\|16573_19204_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	M4T586	Rhodobacter_phage	1.0e-09	22.6
WP_025370434.1\|19484_20438_+	AAA family ATPase	A0A0M3LP72	Mannheimia_phage	4.2e-30	32.2
WP_002850347.1\|20909_21323_+	hypothetical protein	NA	NA	NA	NA
WP_010404305.1\|21378_21537_+	hypothetical protein	NA	NA	NA	NA
WP_010404198.1\|21524_21731_+	hypothetical protein	NA	NA	NA	NA
WP_002850354.1\|21790_22240_+	hypothetical protein	NA	NA	NA	NA
WP_025370435.1\|22241_22679_+	hypothetical protein	NA	NA	NA	NA
WP_010403310.1\|22675_22861_+	hypothetical protein	NA	NA	NA	NA
WP_081291521.1\|23312_24080_+	hypothetical protein	NA	NA	NA	NA
WP_010403314.1\|24055_24352_+	hypothetical protein	NA	NA	NA	NA
WP_081328149.1\|24660_25131_-	HK97 gp10 family phage protein	F1B2Q2	Tsukamurella_phage	1.5e-09	38.4
WP_025370437.1\|25127_26699_-	hypothetical protein	K4NXI4	Burkholderia_phage	7.9e-26	25.4
WP_025370351.1\|27575_28511_+	hypothetical protein	NA	NA	NA	NA
WP_025370350.1\|28500_28800_+	hypothetical protein	NA	NA	NA	NA
WP_025370349.1\|28784_29150_+	hypothetical protein	NA	NA	NA	NA
WP_002849064.1\|29142_29841_+	hypothetical protein	NA	NA	NA	NA
WP_002849065.1\|29830_30295_+	hypothetical protein	NA	NA	NA	NA
WP_002850371.1\|30324_30540_+	hypothetical protein	NA	NA	NA	NA
WP_025370440.1\|30754_36052_+	tape measure protein	A0A0R6PDE0	Moraxella_phage	1.3e-32	32.0
32968:32983	attR	NA	NA	NA	NA
WP_010404385.1\|36051_36909_+	hypothetical protein	X2KRE5	Campylobacter_phage	1.6e-28	29.1
WP_010404382.1\|36908_37664_+	hypothetical protein	NA	NA	NA	NA
WP_010404379.1\|37670_38141_+	hypothetical protein	NA	NA	NA	NA
WP_010404376.1\|38199_38646_+	hypothetical protein	NA	NA	NA	NA
WP_010404372.1\|38659_39553_+	hypothetical protein	A0A291LC41	Caulobacter_phage	6.1e-23	29.2
WP_025370441.1\|39552_40152_+	hypothetical protein	M5AAI8	Nitratiruptor_phage	2.4e-07	37.3
WP_025370372.1\|40114_41215_-\|transposase	transposase	G9CU70	Helicobacter_phage	2.9e-99	52.0
WP_010404250.1\|41192_41648_-\|transposase	IS200/IS605 family transposase	G9CU69	Helicobacter_phage	1.7e-66	82.3
WP_025370442.1\|41739_42105_-	hypothetical protein	NA	NA	NA	NA
WP_025370443.1\|42407_42647_+	hypothetical protein	NA	NA	NA	NA
WP_025370444.1\|42650_42836_+	hypothetical protein	NA	NA	NA	NA
WP_025370446.1\|43026_43233_+	hypothetical protein	NA	NA	NA	NA
WP_025370447.1\|43234_44197_+	CtkA family protein	NA	NA	NA	NA
WP_025370448.1\|44198_45014_+	Fic family protein	NA	NA	NA	NA
WP_025370449.1\|45013_45817_+	hypothetical protein	NA	NA	NA	NA
WP_025370450.1\|45873_47790_+	hypothetical protein	NA	NA	NA	NA
WP_002850926.1\|47967_48606_+\|transposase	IS607-like element ISCfe1 family transposase	A0A1S5RGS9	Helicobacter_phage	2.9e-96	85.6
WP_025370451.1\|48619_49885_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RFS3	Helicobacter_phage	8.3e-119	55.7
WP_081305026.1\|50056_50704_-	type IV secretion system protein	NA	NA	NA	NA
WP_065839583.1\|51312_51492_-	hypothetical protein	NA	NA	NA	NA
WP_025370454.1\|51851_52844_-	hypothetical protein	NA	NA	NA	NA
WP_025370455.1\|53705_53966_-	hypothetical protein	NA	NA	NA	NA
WP_025370456.1\|55009_55252_+	hypothetical protein	NA	NA	NA	NA
WP_025370457.1\|55298_55697_+	hypothetical protein	NA	NA	NA	NA
WP_025370458.1\|55977_56367_+	hypothetical protein	NA	NA	NA	NA
WP_025370459.1\|56366_57071_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_025370372.1\|57142_58243_-\|transposase	transposase	G9CU70	Helicobacter_phage	2.9e-99	52.0

DBSCAN-SWA_2

76291 : 85633

Helicobacter_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010402452.1\|76291_77053_-	DNA adenine methylase	A7YG84	Campylobacter_phage	7.8e-88	62.8
WP_024305522.1\|77106_77661_-	peptidoglycan domain protein	M5AAF4	Nitratiruptor_phage	7.8e-37	44.9
WP_010404353.1\|77647_77998_-	hypothetical protein	NA	NA	NA	NA
WP_010404357.1\|78077_78239_-	hypothetical protein	NA	NA	NA	NA
WP_010404361.1\|78225_78591_-	hypothetical protein	NA	NA	NA	NA
WP_034960263.1\|78587_79658_-	hypothetical protein	NA	NA	NA	NA
WP_010404366.1\|79659_80013_-	DUF1353 domain-containing protein	A0A0E3Y4V5	Fusobacterium_phage	2.8e-08	32.7
WP_010404250.1\|80237_80693_+\|transposase	IS200/IS605 family transposase	G9CU69	Helicobacter_phage	1.7e-66	82.3
WP_025370372.1\|80670_81771_+\|transposase	transposase	G9CU70	Helicobacter_phage	2.9e-99	52.0
WP_002850926.1\|81989_82628_+\|transposase	IS607-like element ISCfe1 family transposase	A0A1S5RGS9	Helicobacter_phage	2.9e-96	85.6
WP_025370478.1\|82641_83907_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RFS3	Helicobacter_phage	1.2e-120	56.2
WP_025370372.1\|84099_85200_-\|transposase	transposase	G9CU70	Helicobacter_phage	2.9e-99	52.0
WP_010404250.1\|85177_85633_-\|transposase	IS200/IS605 family transposase	G9CU69	Helicobacter_phage	1.7e-66	82.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007001

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP006999

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP007000

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection