CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP000574	Leuconostoc mesenteroides KFRI-MG, complete genome	2 crisprs	csa3,cas3,DEDDh	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP000574_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP000574_1

362109-362211

Unclear

Consensus_repeat	Method
CCGACTTAGCTCAGTTGGTAGAGCAC	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP000574_1

>merge|NZ_CP000574|1|362109-362211|CRISPRCasFinder
CCGACTTAGCTCAGTTGGTAGAGCACCTGACTGTTAATCAGGTTGTCGCCGGTTCGAGCCCGGCAGTCGGAGTTTCGCCGACGTAGCTCAGTTGGTAGAGCAC

>NZ_CP000574|1|1|362109-362211|CRISPRCasFinder
CCGACTTAGCTCAGTTGGTAGAGCAC	CTGACTGTTAATCAGGTTGTCGCCGGTTCGAGCCCGGCAGTCGGAGTTTCG
CCGACGTAGCTCAGTTGGTAGAGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP000574.1\|WP_011679269.1\|367827_368556_+\|membrane-protein	unknown	unknown	unknown
NZ_CP000574.1\|WP_025267775.1\|369531_371622_+\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|376463
NZ_CP000574.1\|WP_011679267.1\|365462_366911_+\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NZ_CP000574.1\|WP_025267772.1\|362335_362869_+\|rRNA-large-subunit-pseudouridine-synthase-E	unknown	unknown	gnl\|CDD\|211334
NZ_CP000574.1\|WP_010277907.1\|356620_357160_+\|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|223707
NZ_CP000574.1\|WP_010291225.1\|350413_350980_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP000574.1\|WP_011679260.1\|354898_355297_+\|septum-formation-initiator-family-protein	unknown	unknown	gnl\|CDD\|368217
NZ_CP000574.1\|WP_025267770.1\|359397_360291_+\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|234643
NZ_CP000574.1\|WP_014324308.1\|368533_369001_+\|LytTR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197918
NZ_CP000574.1\|WP_025267773.1\|362938_363655_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
NZ_CP000574.1\|WP_025267774.1\|363703_364651_-\|ferrochelatase	unknown	unknown	gnl\|CDD\|366291
NZ_CP000574.1\|WP_014324309.1\|368987_369398_+\|DUF3021-domain-containing-protein	unknown	unknown	gnl\|CDD\|378668
NZ_CP000574.1\|WP_025267768.1\|350980_354520_+\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118
NZ_CP000574.1\|WP_025267776.1\|371654_373481_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP000574.1\|WP_025267769.1\|355327_356620_+\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|238950
NZ_CP000574.1\|WP_014324306.1\|367030_367831_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP000574.1\|WP_011679262.1\|357186_359289_+\|ATP-dependent-zinc-metalloprotease-FtsH	unknown	unknown	gnl\|CDD\|273520
NZ_CP000574.1\|WP_025267771.1\|360378_361866_+\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NZ_CP000574.1\|WP_004164715.1\|354535_354817_+\|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl\|CDD\|224109
NZ_CP000574.1\|WP_011679258.1\|349643_350288_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341358

Protein	Function_ID	Function_description	E-value
NZ_CP000574.1\|WP_025267775.1\|369531_371622_+\|DNA-topoisomerase-III	gnl\|CDD\|376463	pfam01131, Topoisom_bac, DNA topoisomerase. This subfamily of topoisomerase is divided on the basis that these enzymes preferentially relax negatively supercoiled DNA, from a 5' phospho- tyrosine linkage in the enzyme-DNA covalent intermediate and has high affinity for single stranded DNA.	1.63907e-69
NZ_CP000574.1\|WP_011679267.1\|365462_366911_+\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.71168e-119
NZ_CP000574.1\|WP_025267772.1\|362335_362869_+\|rRNA-large-subunit-pseudouridine-synthase-E	gnl\|CDD\|211334	cd02566, PseudoU_synth_RluE, Pseudouridine synthase, Escherichia coli RluE. This group is comprised of bacterial proteins similar to E. coli RluE. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. Escherichia coli RluE makes psi2457 in 23S RNA. psi2457 is not universally conserved.	2.96131e-102
NZ_CP000574.1\|WP_010277907.1\|356620_357160_+\|hypoxanthine-phosphoribosyltransferase	gnl\|CDD\|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	3.80407e-78
NZ_CP000574.1\|WP_010291225.1\|350413_350980_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	2.28277e-94
NZ_CP000574.1\|WP_011679260.1\|354898_355297_+\|septum-formation-initiator-family-protein	gnl\|CDD\|368217	pfam04977, DivIC, Septum formation initiator. DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.	1.77007e-05
NZ_CP000574.1\|WP_025267770.1\|359397_360291_+\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	1.50913e-101
NZ_CP000574.1\|WP_014324308.1\|368533_369001_+\|LytTR-family-transcriptional-regulator	gnl\|CDD\|197918	smart00850, LytTR, LytTr DNA-binding domain. This domain is found in a variety of bacterial transcriptional regulators. The domain binds to a specific DNA sequence pattern.	1.41805e-17
NZ_CP000574.1\|WP_025267773.1\|362938_363655_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	5.8295e-130
NZ_CP000574.1\|WP_025267774.1\|363703_364651_-\|ferrochelatase	gnl\|CDD\|366291	pfam00762, Ferrochelatase, Ferrochelatase.	9.32504e-129
NZ_CP000574.1\|WP_014324309.1\|368987_369398_+\|DUF3021-domain-containing-protein	gnl\|CDD\|378668	pfam11457, DUF3021, Protein of unknown function (DUF3021). This is a bacterial family of uncharacterized proteins.	1.60212e-08
NZ_CP000574.1\|WP_025267768.1\|350980_354520_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NZ_CP000574.1\|WP_025267776.1\|371654_373481_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.94226e-75
NZ_CP000574.1\|WP_025267769.1\|355327_356620_+\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|238950	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This domain has a strongly conserved motif SGGXD at the N terminus.	2.3734e-74
NZ_CP000574.1\|WP_014324306.1\|367030_367831_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	6.30651e-50
NZ_CP000574.1\|WP_011679262.1\|357186_359289_+\|ATP-dependent-zinc-metalloprotease-FtsH	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP000574.1\|WP_025267771.1\|360378_361866_+\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NZ_CP000574.1\|WP_004164715.1\|354535_354817_+\|RNA-binding-S4-domain-containing-protein	gnl\|CDD\|224109	COG1188, COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) [Translation, ribosomal structure and biogenesis].	2.99369e-29
NZ_CP000574.1\|WP_011679258.1\|349643_350288_-\|CBS-domain-containing-protein	gnl\|CDD\|341358	cd02205, CBS_pair_SF, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.94521e-07

>NZ_CP000574.1|WP_025267771.1|360378_361866_+|lysine--tRNA-ligase
MAEEKALNDQMLARRQKLATIVSDLHLDPFGKRFERTANAQELHNLYDASSLEELENAKHEVVIAGRMVAKRGAGKVIFADFRDVSGKIQVYARRDDLADNYPIIKRADLGDFLGIKGIMMKTEAGELTVLATELTHLSKALRPMPDKFHGISDVETRYRKRYLDLIANEDSFKKFQERSHIISAIRAYMDRNDFLEVETPILQTEAGGAAARPFITHHNALNIDMYMRIATELYLKRLVVGGMERVYEIGRIFRNEGMDPKHNPEFTTMESYAAYMDFTDVMDETEGIFKAAASVVSDDLKITYQGTEIDLGTKFARKHLVDLIKEQTGIDFWQEMSVEAAQKLADDNHVKYEKYWGVGHIINAFFEEFVEDTLVQPTFVYGHPVEVSPLAKKNTDDPRFTDRFELFIMGSEYANAFTELNDPIDQRARFEAQAAERENGNDEAEGIDEDFIEALEYGMPPTGGLGVGIDRLVMLLTDSDTIRDVVLFPTMRPE
>NZ_CP000574.1|WP_025267770.1|359397_360291_+|Hsp33-family-molecular-chaperone-HslO
MADQFIKAITKNKYFRTFAVNGTNLVHQAAQIHETSRIAAVVLGRSLLATTLAAQAVLKGEETLSTKINGRGPIGNVVVESDAKGSVRGYVTNPNLETLINEAGQLDVAKAVGKNGFLQVTKFAPYSDPYIGQSQLVSGEIGDDFTYYLAQSEQTPSVIGVSVYMNSDDTVAGAGGFLVQALPDATDEAIDQLEVALKNMKPLSEMIQERYTPLEVLEEIFGKGEVEILQTAGIGLAAEPSKDAYAKMLLTLPASEIQAMIKEDHGAEIVGKFSGKRYFFTEEQLSEILRQIEKNNE
>NZ_CP000574.1|WP_011679262.1|357186_359289_+|ATP-dependent-zinc-metalloprotease-FtsH
MNNNKGGFLRSSVFYIFIFLAVVGMVYGLFGNDKTTTKTITSSEFIKALNDKELKSVTVQPGNSIYNVTGTYKKAQTATKDKGLSLFQPTQKVTKFTSTLLPNDASLKSVTDAATKTKTELVTKQAENSGFWLNLLVSLVPVLLIVAVFYLMMNQAGGGKGGQGGMMSFGKSKAKPSDPKDNKVRFADVAGAEEEKQELVEVVEFLKAPKKFVNLGARIPKGVLLEGPPGTGKTLLAKAVAGEASVPFFSMSGSDFVEMFVGVGASRVRDLFENAKKSAPAIIFIDEIDAVGRRRGTGMGGGNDEREQTLNQILIEMDGFEGSEGVIILASTNRSDVLDPALLRSGRFDRKILVGAPDVKGREAILNVHAKNKPLADNVDLKAIAQQTPGYVGADLENLLNEAALLAARRNKSKVDAADIDEAEDRIFQGPAKTNHNMSESERRTTAYHEAGHALVGLVRSEASVVRKVTIVPRGRIGGYALMTPKNDRYNLKYSEAKEQLAGLMGGRASEIFMFNEASSGASNDFQQATGLARQMVTAFGMSDKLGMVQLEGNASVGYADQAGNRAYSEETARLIDEEVRRLAREAFDDAIAILRDNKDKLTAIAEALLEVETLDEKQIKDIYLTGTFTRKDIQDDTELAKAKSFEEAKAAADAKDSQAEQRFEKQDEEKSSDDHSESKNEDTDSTDKSETDDNNTENK
>NZ_CP000574.1|WP_010277907.1|356620_357160_+|hypoxanthine-phosphoribosyltransferase
MDNDIQEVLYDQESIQKAAERLGKQITQDYAGSTPLFLSVLKGAYLWTADLLREVDLYAELEFIKISSYHGGVSSSDEITLVTDVRSDVRGRDVIILEDIVDTGQSLLFLKELLAKRGAKSIKVATLLDKIEGRKVEVDADYAGFNVRNEFVVGYGLDYEEHYRNLPYVGILKKEVYTK
>NZ_CP000574.1|WP_025267769.1|355327_356620_+|tRNA-lysidine(34)-synthetase-TilS
MTEKILQTIQQYNWPETVIVAVSGGVDSVVLVHALSKTKANLVIAHVNYRLREESDDDADFVRQLATQTGAIFEEQVWQHIPDHAVEKAARQFRYDFFEELAQKYHTNTIAVAHHADDQAETVLLKMIRGGQLQQMGGMQTKNHKVIRPFLSITKQELITYAQDNQLGWRQDKTNFDVDYTPRNLLRNDVLPKLTTINQRAVRHINNMAAQILQQQRLIDNQAKIYANDIQDWQKIPTLWQLPTLKYWLQKNKLFNIKENQLQQMIQLLSNTHKPNGKIALADNFEFIKNYQKISIQKQQNMAQVLTPVMLKLNQWHSFAKTTFMWTDNVPMNGQSFIKFQLTRSLPYLSLRPAKASDKIALINGHKNLRRLAIDEKLTPQERTMMWVLATADDEVIAVHLRSNQWRVNADFAVKENTQPYWLVCQIEET
>NZ_CP000574.1|WP_011679260.1|354898_355297_+|septum-formation-initiator-family-protein
MAGNFKRRQSNITPLNPAIAREIKKSERANSEAAKHYRKAHARREKKILLFGGLIAIIFVVQLLIGQVKLHAANQELTNTQDRLEKVQKTNTDLTADTKRLKDATYLQQLLRDKYGYSKQGELVYNLPSDNN
>NZ_CP000574.1|WP_004164715.1|354535_354817_+|RNA-binding-S4-domain-containing-protein
MRLDKYLKISRLIKRRTVAKEIADQGRISINGKVAKSSSDVSTNDELEVRFGNKTLTVKVLKIVETTKKEESADMYEVISEKFQQDFRKIGDE
>NZ_CP000574.1|WP_025267768.1|350980_354520_+|transcription-repair-coupling-factor
MTLIDFLSDTVTIKKLNEQATVGSAQLLLGVNGTARAASIAALYRKNPRPMLIISDTQVHADQFFDDLSSLLEDLVYNFPAEESIATEMAISSSELRLQRVQTLLALKTEKPIIVVTSLAGAERLVPKKQSLEQAHLHVKVGDAYNLNVIKNTLMMMGYTPTKLVQTPGEFAHRGSIVDVYPITFDDPIRLDFFDDELDQLKSFDVATQKSTTSFDEINIEPATDFIVSEHQYDQAKLAIESAFSDYRTNLSGVDKKHATDGFAPTQYMLNERERGSVLVPYAPFFFDGQTTLLDYFPTDSLIIIDEYTRLMETRLQQMTRDQEWIEQQIEAYQLLPKQTWRTEITDLLASNQHATIYLANFQRGLNRIKFTNVEEVTTRPANQYYGQIPALKNDLIYAQESGITMVLLIPDAKRRANFSRSLSELEVPVTETRDIVKNQVQIMPGELSAGFEWPKLHLTVLTTHELFTQAKHSAPRTRKIANSERLKSYNELNVGDYVVHINHGIGRYEGLQTIEADGGKQDYLTIAYQQNAKIFIPVTQLNLIQKYVGASDVAKKPKLNKLGGSEWAKTKRQVAAKIEDIADDLLELYAKREAQQGYVFPPDDHAQIKFDDSFGYPETPDQIRSIEEIKVDMQKLRPMDRLLVGDVGFGKTEVALRAVFKAAHSGKQVAFLAPTTILVQQHYETMLARFSDFPEIKIGVLSRFQTPTQNKMIIEQLQNHEIDVVVGTHRLLSKDVDFSDLGLLIIDEEQRFGVKHKERLKQLRTSVDVLTLTATPIPRTLNMAMVGARDLSVIETPPANRYPIQTYVLAMDWKIVRDAIEKEIARNGQVFYLHNRVADLDRIVSQIEELIPSARVAAIHGQMSETQLESILYDFLNGQYDVLVTTTIIETGVDIPNANTLIVENADHMGLAQLYQLRGRVGRSTRLAYAYFTYPFTRTPSEEAEKRLEAIRDFTELGSGFRIAMRDLSIRGAGDLLGKQQHGFIDSVGYDMYTQMLKDTVAQKQGKQVTTSQPETDAELILGVLAYLPDEYVSDNAQKIELYSRIRQARTDAEFEDIESDMLDRFGEMPDEVARLLLVGQIKQLADQSQITNIRRQRKQLIMTFNETATKNLAGEAIFETMVDVPLKAAVRTEEGNLQVIFTVNDVAESSIWLNILRNFLLVIINKLSAKTLNELHH
>NZ_CP000574.1|WP_010291225.1|350413_350980_+|aminoacyl-tRNA-hydrolase
MKFIFGLGNIGAEYDQTRHNIGFMAVDAFATANHMSFSPSKQFALVAKTIIGGESVMLVKPTTYMNDSGKAVRAILDYYDGDVDDVLVLVDDMDLPFGKMRFRAKGSAGGHNGLKSIMTHTGSQTFLRLKFGLGHPVHEQNVVVNYVLGKFTAAEKPDIDAMLDRSTQAIADWIQGATAPELSNRYNG
>NZ_CP000574.1|WP_011679258.1|349643_350288_-|CBS-domain-containing-protein
MFQKSLVIPKSELTTVTENATIQEVYDIFNDPENAHTRTMPILDESGKLFRGNVYKQHVFEHVAKNGNMNLPATAIMRNSTKFIYTNSKFYEVFFAIRDLPFIAVLDENHQFYGIFTHDALMDLLSQSWSVRSGGVAIAISTHNTQGDLSKISKIITRYSNIESLLTIQSELKPLTVLFTLPLQEDSEQLEKLIKRLEKKGYHVSSVENLNRFR
>NZ_CP000574.1|WP_025267772.1|362335_362869_+|rRNA-large-subunit-pseudouridine-synthase-E
MIVLFNKPYNVLTKFTDAEGRQTLADYIDIPRVYAAGRLDMDSEGLLLLTDSGKLNHELTDPDNKAYKTYVVQVEGVPTKSQLKQLEQGVALKDGLTLPAKVKRIPYPKWLWEREKPIRIRKNQPTSFIQLKIKEGRNRQVRRMTAAVGIPTLRLIRTHIGEYHIADLKPGQYRIVK
>NZ_CP000574.1|WP_025267773.1|362938_363655_+|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWENIKMKKAQTDGAAAKVNSKYGIEIYAAAKQGGSSDPEANSTLKFVIERAKQAQVPKHVIERAIEKAKGSGDETFIEGRYEGFGPNGSLIIVDTLTSNVNRTATNVRTAFNKNGGTYGAAGSVSYLFDETGVIVFEGEDADATLETLLDAEVDVRDAEQQDDHIVVYTEPTALHQAIAALRESGVSDFSTTEISMLPQSEMTLAGEDLEIFEKLIDVLESDDDVQKVYHNVES
>NZ_CP000574.1|WP_025267774.1|363703_364651_-|ferrochelatase
MNKKGLLLVNLGTPDSPHPDDVKAYLKEFLSDTNVIQMPRLLWQPILRGKILPKRSFKSAELYQKIWRKDGSPLMVYAKKQVEQVQQLQPNWIVRCAMTYRKPNIAETLKEMRLAGAEDIVVLPLFPQYSVTSTQSVIDQVRKADKNINIVKSFYNDEAYLDLLARDIREAWAKNDYDRLIISYHGVPESYVRRGDPYVDHCTATTQGVLERVGPLTPDNTHQVFQSRFGPTEWVKPYLSDTLRSLPSQGIKRVLVATPAFVADCLETIEEIHVENHDIFKQAGGEVFDVVQPFNEHIDFSKYIASLANRHFAQN
>NZ_CP000574.1|WP_011679267.1|365462_366911_+|NCS2-family-permease
MEKLFQLKENKTTVRREIIAGITTFVSMAYIFFLNPQILGQAGVPTQAVFLAAILVAVFGTLFMGLFANVPFALAPGIGMQAYFTYTIVFGFGFTWQQALAIVFLVGVVDIVITLTHGRRAIVKGIPTELKAAIGGGIGLFVTYIGLKNAGFINFIVDPSNIMTLNGKPFTGEVHGAVNSILANGGVTPELTKFNNASTLLALIGFVILVVLVMRKVPGAFLISLIVTTLIGIPMGVTNTHIGAGTSVSHAFGELGQVFGQSLGAQGLGSLFNNWHHASLALVTIFAMGLTGLFDAIGTLIGIGNQTGIFSKEDQKSFESSNGFNSKMDRALVVDTFTTAFAGIVGTSNTTTFIESASGVAAGARTGLANVVTAAGFALMILFAPLVGVVPTAATSPLLILVGIMMMGEFKKISWESLEVALPAFFTSVFMAFSYSISYGIAAGFIFFIIVKFALGKFKEVSPVLLIVSAFFLLNFAVLAFM
>NZ_CP000574.1|WP_014324306.1|367030_367831_+|ABC-transporter-ATP-binding-protein
MLNIKNLSVSYGRKVALTVPKLSINKGEIIGVMGKSGSGKSTLVNSCLGLIPFKGQVRIDTDDVGILMQEQHYVDTMTNQKMIEGMLNTRIKRDKKLTELINFFDFSDQLSLHFKNLSGGQKQRMSLIMVLYQEPELLFLDEMTTGLDFESRQALISQLKIYFKQHQTTVLMVTHYAQEIEALADKLLVIHDGQVKAFDEPKNLFKQYIGYSAFIVDNHTEKSIKVQQPEDEYKVACRLIDDGDDFRRTQSDIELVYTEVMKGQRA
>NZ_CP000574.1|WP_011679269.1|367827_368556_+|membrane-protein
MIKKRKLVFEFQNLLGNIITLFFGFAFAPMMALVFGNSYANVPQALNQLYLGFFCTIPLSMVFVGFSSLFSQEVEQGFTLRAELFGYSRVSQALHKFMALTVFVLLSSIIYSWIFLSHFNLPLPNAVIIGQMAIFQILNTAVYFIIVFILTTILKKFSRVYGISMISYFAIMIISGIMGNMDVGKLGDYLPIKLFVTNYTNHLNDTDYISGKIGLYLLILLGILGVILKVIVRNKNGNKHQY
>NZ_CP000574.1|WP_014324308.1|368533_369001_+|LytTR-family-transcriptional-regulator
MEININIDDKLKDVQVVISGSDIEQLADIAQYLKSRNTPSRQLAIKTADNIRVVDKEDIILVESYGNDLTFTLKNNHKITTRKTLKRFLEENQKSDFVQISKSEVMNLSYLSKMESAFSGNYYAFLTNQARVTVSRRFIKGILKRLEGSAEDEAF
>NZ_CP000574.1|WP_014324309.1|368987_369398_+|DUF3021-domain-containing-protein
MKHFKEAIVYLLVGIGVGSFISLLSFTLNHATPSMKQFGLLMTMSAIMGLLSLIFEYDKITFITQLISHFILEMLTYGFFIWLTFGSAVITFTNIPTFVITYVIIFIYFRKQGRDNARRINEQLQKNKPKKSDSTN
>NZ_CP000574.1|WP_025267775.1|369531_371622_+|DNA-topoisomerase-III
MPNYLILTEKPSAAANFVKALGGKTGVFGDFTYKITNLRGHVMTLKDPEEMVAEDLKKQYKSWLVKHLPWNLEDFSWARTYIRQRNIRTGKIESTKKLIDELKKESKSGYDAIVIATDTDPSGEGELLAWEALDAIGWRGQVLRANFMDESVSGIQKAMHQLRNVSDKMADGEYVKGESRNRWDFASMQLTRIATTAAKKEGFKVVAREGRLKSVIVWRIYQQLAAIKNYIKTPYFEVKFKDPAGHIFGRVTPQGEVIPWRFATKEQAKVDFNNYHETEVINEKHQTRTQAPGKLLDLAGLASILAPRGFSSKEVLSTYQKMYEAQIVSYPRTEDKTVTPEQFNELLPLIDQIAGVVGVDKNLLTHRSPRKTHVKSQGAHGANRPGENVPQTTQSLAKFGSSGPAIYEVLAKNYLAMLAEDYVYDHVTANLKDYPEFKTAFNIPIKLNFKLVYDSQKAIKVEEGEEEESISGQLGPQARPYLHEGANPKPQVPTTKWIMAFLEKHNVGTGATRVSTLSEMSRGTKAMLTEKRGKLGLTETGNVSAIMVKDTWIASPKITKRLFEMMDQVGRFEMTMVQVLDSATKVVEHDMPIMLDNAQTLETLLGKPKPSIKKPRKTSEKMTGIWQGQEITFAREWSGHVFTDEELQKLLTGSEVSFPAKSKRGKSYTAVGKMAKQTFKGNTFYGFKLNPKTKKA
>NZ_CP000574.1|WP_025267776.1|371654_373481_-|MFS-transporter
MIKSTKRLGFIGLTIAMFMGTLDSTIVNIALPKLMTTFNTNLAGVSWVATTYTLALAVFMITATKLGDKFGRKKLMIIGLLLFAGSSAACMFAPSLMYLLVFRSFQGLGGAIITPLVLPMGVELFGKQHMSKIAAIVGAITALAAAGGPAAGGFILEYMSWHWIFGLNVPIGLISLLLVLLFTKESFDETLVGHFDISGMLFLTISLTGITFGLLEGREYGWTSTLILSSFLAGIIGLIAFILIELKVSSPIVELNLFRDKTFTSSCIIYFATGFALVAPAVIFNYYLQNVLNYDALHAALMIIPVSLAIAVTMPLATRLSDRISAIPVNLIGMLLIAGSLLLFSFITTTTPKRIMIVFSIIIGSGFGFSTVSFVSSVRHLPKSKTGIGSGITNASRQIGTCLGLAVLITVLNTNISTAKSHIQNHSIAIINRKTLSPNIKNTAKSGIRQIFSSNDQKNVNYTSRQKQFTKQLKHAALNKSSLPRPKKGTDYRKLYDATFKISEGNQKINDSLQKLAGTTTTNKVLNNSIIALSDGTLTLLNGQKNMLEAIKLLAQRDELKSSLSEIKKEKNTSLSHAFSKTYVICAFLLLLCSPIALLSDKRQKKTH

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Crispr_ID: NZ_CP000574_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP000574_2

1254532-1254617

Orphan

Consensus_repeat	Method
CGTGCTCCATCAGAACCAAAATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP000574_2

>merge|NZ_CP000574|2|1254532-1254617|CRISPRCasFinder
CGTGCTCCATCAGAACCAAAATAATACGTATGACCCCAATTTCTATAAAACTGGTTTGTATACCGTGCTCCGTCAGAACCAAAATA

>NZ_CP000574|2|2|1254532-1254617|CRISPRCasFinder
CGTGCTCCATCAGAACCAAAATA	ATACGTATGACCCCAATTTCTATAAAACTGGTTTGTATAC
CGTGCTCCGTCAGAACCAAAATA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP000574.1\|WP_025268257.1\|1243306_1243777_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274933
NZ_CP000574.1\|WP_155246463.1\|1242916_1243306_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP000574.1\|WP_025268261.1\|1253161_1254211_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226122
NZ_CP000574.1\|WP_025268266.1\|1258214_1258985_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP000574.1\|WP_025268265.1\|1257129_1258179_-\|DUF916-and-DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_CP000574.1\|WP_025268271.1\|1263836_1264712_-\|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl\|CDD\|130274
NZ_CP000574.1\|WP_025268253.1\|1240122_1240749_-\|sugar-transferase	unknown	unknown	gnl\|CDD\|376775
NZ_CP000574.1\|WP_025268267.1\|1258977_1259376_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP000574.1\|WP_025268268.1\|1259455_1260910_-\|choice-of-anchor-A-family-protein	unknown	unknown	gnl\|CDD\|275059
NZ_CP000574.1\|WP_051394930.1\|1249031_1253003_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|334895
NZ_CP000574.1\|WP_025268270.1\|1262182_1263220_-\|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|224013
NZ_CP000574.1\|WP_025268251.1\|1238086_1239472_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP000574.1\|WP_014947523.1\|1263233_1263827_-\|dTDP-4-keto-6-deoxy-D-glucose-epimerase	unknown	unknown	gnl\|CDD\|376414
NZ_CP000574.1\|WP_025268255.1\|1242356_1242899_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239109
NZ_CP000574.1\|WP_025268252.1\|1239481_1240105_-\|capsular-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453
NZ_CP000574.1\|WP_025268264.1\|1256034_1257006_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP000574.1\|WP_025268269.1\|1261290_1262133_-\|dTDP-4-dehydrorhamnose-reductase	unknown	unknown	gnl\|CDD\|367904
NZ_CP000574.1\|WP_025268254.1\|1240814_1242260_-\|flippase	unknown	unknown	gnl\|CDD\|240533
NZ_CP000574.1\|WP_155246464.1\|1244604_1248411_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|334895
NZ_CP000574.1\|WP_025268263.1\|1255506_1255902_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP000574.1\|WP_025268257.1\|1243306_1243777_-\|hypothetical-protein	gnl\|CDD\|274933	TIGR04035, glucan_65_rpt, glucan-binding repeat. This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.	0.0088041
NZ_CP000574.1\|WP_025268266.1\|1258214_1258985_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	1.21639e-48
NZ_CP000574.1\|WP_025268261.1\|1253161_1254211_-\|acyltransferase-family-protein	gnl\|CDD\|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	1.62569e-11
NZ_CP000574.1\|WP_025268271.1\|1263836_1264712_-\|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl\|CDD\|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	4.67713e-179
NZ_CP000574.1\|WP_025268253.1\|1240122_1240749_-\|sugar-transferase	gnl\|CDD\|376775	pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.	3.00809e-82
NZ_CP000574.1\|WP_025268268.1\|1259455_1260910_-\|choice-of-anchor-A-family-protein	gnl\|CDD\|275059	TIGR04215, conserved_hypothetical_protein, choice-of-anchor A domain. This domain may occur as essentially the full length of a protein, except for an N-terminal sequence and a C-terminal protein-sorting signal such as PEP-CTERM or LPXTG. Most often, the putative surface protein is longer and contains repetitive sequence regions. This is one of very few domains for which both anchoring domains occur, and designated choice-of-anchor A domain. The best characterized member is Bacillus anthracis protein BA0871, a collagen-binding protein with five CNA-family protein B-type repeats toward the C-terminus and an LPXTG cell wall attachment motif.	2.64695e-09
NZ_CP000574.1\|WP_051394930.1\|1249031_1253003_-\|hypothetical-protein	gnl\|CDD\|334895	pfam02324, Glyco_hydro_70, Glycosyl hydrolase family 70. Members of this family belong to glycosyl hydrolase family 70 Glucosyltransferases or sucrose 6-glycosyl transferases (GTF-S) catalyze the transfer of D-glucopyramnosyl units from sucrose onto acceptor molecules, EC:2.4.1.5. This family roughly corresponds to the N-terminal catalytic domain of the enzyme. Members of this family also contain the Putative cell wall binding domain pfam01473, which corresponds with the C-terminal glucan-binding domain.	0
NZ_CP000574.1\|WP_025268270.1\|1262182_1263220_-\|dTDP-glucose-4,6-dehydratase	gnl\|CDD\|224013	COG1088, RfbB, dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_CP000574.1\|WP_014947523.1\|1263233_1263827_-\|dTDP-4-keto-6-deoxy-D-glucose-epimerase	gnl\|CDD\|376414	pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyze the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose. The EC number of this enzyme is 5.1.3.13.	8.80402e-53
NZ_CP000574.1\|WP_025268255.1\|1242356_1242899_-\|hypothetical-protein	gnl\|CDD\|239109	cd02549, Peptidase_C39A, A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic). The cleavage is mediated by the transporter as part of the secretion process. Bacteriocins are antibiotic proteins secreted by some species of bacteria that inhibit the growth of other bacterial species. The bacteriocin is synthesized as a precursor with an N-terminal leader peptide, and processing involves removal of the leader peptide by cleavage at a Gly-Gly bond, followed by translocation of the mature bacteriocin across the cytoplasmic membrane. Most endopeptidases of family C39 are N-terminal domains in larger proteins (ABC transporters) that serve both functions. The proposed protease active site is conserved in this sub-family of proteins with a single peptidase domain, which are lacking the nucleotide-binding transporter signature or have different domain architectures.	4.0613e-13
NZ_CP000574.1\|WP_025268252.1\|1239481_1240105_-\|capsular-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	2.39038e-10
NZ_CP000574.1\|WP_025268254.1\|1240814_1242260_-\|flippase	gnl\|CDD\|240533	cd13128, MATE_Wzx_like, Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	2.30518e-50
NZ_CP000574.1\|WP_025268269.1\|1261290_1262133_-\|dTDP-4-dehydrorhamnose-reductase	gnl\|CDD\|367904	pfam04321, RmlD_sub_bind, RmlD substrate binding domain. L-rhamnose is a saccharide required for the virulence of some bacteria. Its precursor, dTDP-L-rhamnose, is synthesized by four different enzymes the final one of which is RmlD. The RmlD substrate binding domain is responsible for binding a sugar nucleotide.	1.161e-127
NZ_CP000574.1\|WP_025268265.1\|1257129_1258179_-\|DUF916-and-DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	4.33102e-54
NZ_CP000574.1\|WP_155246464.1\|1244604_1248411_-\|hypothetical-protein	gnl\|CDD\|334895	pfam02324, Glyco_hydro_70, Glycosyl hydrolase family 70. Members of this family belong to glycosyl hydrolase family 70 Glucosyltransferases or sucrose 6-glycosyl transferases (GTF-S) catalyze the transfer of D-glucopyramnosyl units from sucrose onto acceptor molecules, EC:2.4.1.5. This family roughly corresponds to the N-terminal catalytic domain of the enzyme. Members of this family also contain the Putative cell wall binding domain pfam01473, which corresponds with the C-terminal glucan-binding domain.	0

>NZ_CP000574.1|WP_025268261.1|1253161_1254211_-|acyltransferase-family-protein
MAVNKRIQWIDIARGIAILLVIIGHSLGNYWPGYLGNFIFVVHMPIFFILSGYLYHLKEETTLFKSGVKNLLIPYIGTVVIELLCLIISKFFKDGFFYSRIGSVKGLLLSSFYGIGVPIRTPFNIDIVGIGAIWFLMAFFGGTLIFNLIMRLKIADHYKFLIVIIVSLFGYTLNQYITLPFSLNISMAVQIFFFAGYWIKKIHLIAKLKWWHYLLFMVFWIYVASIGLFVVSDISSPNIIINYIAGITSSLVLIKFSIFIENLNKIQLTKSLTFFGANSLAILAFHLIDLDSVTLWYKITQHLIPYLPYLLVVLIGIIYRILFVIFAVMVVKKLPLAKTIFFPRKFKKI
>NZ_CP000574.1|WP_051394930.1|1249031_1253003_-|hypothetical-protein
MRKKLYKSGKLWVAAAAASLAIAVGPNVVDADTTTPTTQTTTTVAGAKQSTSVDDNKVVTEVTGNNGVTSDNKTTTSNNSADNNGSKTDANGVGNPTDISNIPTDSVKINANGQTTTVINPTTTNSGSTNNKTTAVDQTKNDTKNNTTTIITTPEEKVETPKLKLVGGVDGYYDSDENGNYQFKLYKNNDHIKSNDDKPVTGLQTIDYFVQYFDTDGTQVKGAYRTVDGDKYYFASGSGNALKQATVVPNENGTGSKIVGFDNNGKVVKNGFSSDNAGNTYYFDENGNFVTGWRTVNGQQYYFEENGTLVKSGQKTVGDNVYYFDSSDGHAIVGNKSQYTEGLTSQNDDFTEHNAIVNNDSKSIDNVNGYITAASWYRPKDILENGQTWVSSTETDQRPLLMTWWPDKNTEADYVNFMAKRIATVNSDGKIYSALDSQEVLNKQAEAIQIEIEKYISQNATNYTLELKKLFGDFIATQPNWNITSEDVSTDHFQGGALVYSNSTMTPWANSDYRFLNRTPTNQKGDVYGDKGGYELLLANDVDNSNPVVQAEQLNWLYYLTHFGEITANDPDANFDSIRIDAVDNVDADLLQIAADYMKSAYGVGDNDAITNKHLSILEDWSDNDFKYVSENGNNQLTLDKKVQDNLLNVLTKFPTNRQNMETIINNRNVDRKNDDGSQTVTPNYSFVRAHDSEVQTVIARIIQDKFPDSGSGLIQTTDEINKAFEIYNADQLLADKHYTHYNIPSAYALLLTNKDTIPRVYYGDLFTDNGDYMANTTPYYKAIDALLKLRVKYVSGSQTSEVDKNHTDVLTSVRMGNNTTEGVGIIVSNNPDLNLGNDEITLNMGQAHANQTYRAALLTTDTGITVYNSDEDAPIATTNSKGQLIFSAKEINNQRDTNIRGVGKDNNQVSGYLAVWVPVGADINQNATTQASTETTTDGKTLHSNAALDSNLIYEGFSNYQTIPDGSDPEKYTNAIIAKNVQTFKDWGVTSFQLAPQYRSSEGTSFLDETLKNGYAFTDRYDLGFDNNPTKYGTAEQLRAAIKALHSVGIQAMADFVPDQIYTLPGEEAVTATRTNNQGVYKQDSDFNNLVYIAKTKSSGQDYQSKYGGQYLDLLKDKYSNLFEDKQLSTGESIDPSEKITQWSAKYFNGTNIQGSGKYFALKDFASNQYLTISDSGTSVLPKQLTNQKTQTGFYKDDKGIGYYSLSGYQAKNSFIQDDQGNWYYFNNDGYMVTGYQNIDNKDYYFLQNGVKLNVNGLVSDNNQTYYFKNNQLQKGSQTVQGITYFFDSQTGLMKKDYFDFAADNKVYYYGTDGVRYTNRVL
>NZ_CP000574.1|WP_155246464.1|1244604_1248411_-|hypothetical-protein
MRKRMYKAGKSWVVAAATFAATAMIASGGVSANDTNQQNNATLQVSPTKNDNSVAKNTTSTANVAKVDITTDNTRDISSANNVNNLITNQYKENSNGSWSYYDNNGQIVKGLQTINGNIQYFDSTTGEQVKGQTLTIDGVIYSFDKDSGNGTKTEVASLPTTGSYATKDGSNWQYEDQQQQPIKGLYTDKGNLRYFNETDGTQVKGTVVSVDNNTYYFDKDSGNGQLVPSVTGGQYGTIQLNNQTVWVYRNANGEIVKGLQNINGNIQYFDPNTGEQLKGKVATVNGVTYYFEASDGNLVGTVSDGLVTVNGQIQYFDPATGEQAKNKQVIVNNVTYYFDDNGYGQYLFTNAILSTTPDAYSAHTQAYNTDQSSFTNVVDGFLTADSWYRPKEVIADATGSAWQTSSENDYRPIITVWWPNKNVEVNYLKLMQDNDLLSTQTQFTIFSDQYTLNEAAQAAQNEIEKRIYREKSTDWLKDLLFEAHGDTPSFVKQQFIWNKDSEYQGAGGGNLWSLQGGYLKYVNDSETSWSDSTSRKHDYYEYLLGNDIDNSNPQVIAENINWLYYLMNFGSLTGNDDTANFDGVRMDAVIYMKGEASTKVYQFLHKSDELTKNEKIANEHISIVEDGTDETTKNNSALIVSKWNENIASSLAKIASGKDTSLEALVKTDEKTSVSRIMNSSVESDVNPNYSMIRSHDRGSQDEVINASKVANNDQSIALDNINLNQLENGLKLYYEDQASPTKNYNYYNIPASYALLLSNKDTVPRLYYSDMYQDYDQNPDTPQQYMSKPTIYYSAIDALLKARIKYVAGGQSMAVEKVGDNKDQEVLTSVRYGKNVMTATDTGTVESRTEGMGVIVSNNTKLKLSTTDQIVLHMGAAHANQAYQALMLTNDEGIQLYNDNAPVVWTDHNGDLVFNGNDINGQKNTSIKGYFNPQVAGYLAVWVPVGATDTQDARTKASTNATTDGKVFHSNAALDSNVIYEGFSNFQPIARNHNDFSNVKIAENVDLFKKWGITSFELAPQYRSADVSDLVGSTFVDVVTKNGYGLSDRYDLGFVTPTKYGSDSDLRNAISSLHAQGIQAMADFVGNQIYALNDGQEVVTAQRSDMFNNTLNNAFGTELYVVNSIGGGKYQAKYGGNYLEEIASLYPDLFTNQDGTKIDINTKIKQWSAKYMNGTNVLGRGMGYVLKDWNTATYFKLDGEHTVLPAALTLSGLKVENGVTYYYKNNERQTGTQTVDDVTYFFDPKTGAMKKDYFDFTADNKVYYYG
>NZ_CP000574.1|WP_025268257.1|1243306_1243777_-|hypothetical-protein
MYKSGKYWIAAVAAIFSMIVDYDSVNADVNETISIQQTSTARDGSKNTGIVETASNEQRSEASEASKAETSEASKADSKSTDKPNSNNDKHSDSLNETTISGMKTDNNETYYYKNKQLQKGSQLIDGHTYYFDTETGVMKKTTLNLLPIIKFTTMV
>NZ_CP000574.1|WP_155246463.1|1242916_1243306_-|hypothetical-protein
MVYVIQISSMLTGVKHTTLAMMALGTLTSFMATGVKLITLAMMVLDTLTSFMAIGVKPIILVMMALDTLTSSTLTGVKHTTLVMMALDILISFMVTGGTRIILAMMAPDILTNFTVTGGTNIILMAMVF
>NZ_CP000574.1|WP_025268255.1|1242356_1242899_-|hypothetical-protein
MVNNIKYASNDKGILSVQSLNKPYYYSQFNPEWSQTWFNDHIFAMDGCVPTSIAMVLKGSYNINVNPRQVANTINTFHDNVGATGIDLQRMVSAYGYNAKSLASTQAKKALIQGTPLIVLVNVGIGHAVVLNGYSNGATEVFDPYDKKFYNGWYSLEGILNRLSNDSHDWDAGTPVFAIS
>NZ_CP000574.1|WP_025268254.1|1240814_1242260_-|flippase
MQVAKNYLYTAAYQLLNIIAPLITMPYLARVLGRNGVGIASWTNSFVTYFLLIASLGIVTYGSREIAYVKDNKQARQQKFWEIQIIHTIAGIFSLALYFLFLKYGVQLNNNIEDNQIYLILQTWVIISGILDISWYFMGMEDFKKTVLRNALVKIAMTVLIFVLVKTPNDIGNYILLLGLSQVFGNLSMWFYLFKKISLPNWHQLDLKEHVKPIFMMFLPTIATQVYLQLNKTMLPFFTNSTDSAGFYDNADRIIKVSLALVTSVGTVMLPRMSAQFAKGQFDKMKQNITQSMDFVSALSVPMAFGMAAIAPTAMIWFLGEQFKVVGQVIVLLSPIIIFIGWSTVIGTQYLVPTKRLNEFTLSVTIGALANVLLNFWLIYVAGVNGAAVATTISEFLVIGYQLYVTRKDMNVWHHFSEMWRYIIAGLGMYMLVTMISQYLEINIKSTSIELVLGIFVYVLILIILRAPILKKIPLLNKIAK
>NZ_CP000574.1|WP_025268253.1|1240122_1240749_-|sugar-transferase
MKRKLGYLTAKRGLDISVSLAAMFLLSPVFAIIALIIIKDKKTSKVIYAQERVGQYGKRFKIYKFQSMVDNADKILKQDADLYAKFVASGYKLPTAEDPRITKFGAFLRKTSLDELPQFWNTLNGTMSIIGPRPVVEDELVEYGDDIDKFLSVKPGVFGLWQASGRSNIEYPERAQMELDYVDRANLRFDFYILFKTVIAIFKRDGAF
>NZ_CP000574.1|WP_025268252.1|1239481_1240105_-|capsular-biosynthesis-protein
MSFSLIDLVKRLLKNSWWILILGIALGASLYTYAKHSVLTAYTAERYVIVAKNNTGVKDPNSRVQADQILINTYKKIASDPSVVNQAKKLSAVSVTKKEIVSAITISQPDQTLMMRFSASAATAKKSVAIANAYAKAFSIEGSKLYPDMAKPLLLSSAKKADVLSGTVYSPKKLAVFGFSFGVILGSFIVLIMGIFQNYKQLKKTIK
>NZ_CP000574.1|WP_025268251.1|1238086_1239472_-|hypothetical-protein
MGAFLLPITFFTKTFGGKIESAETLSMFAFPAFTLLLLLQLFRYPKRVHDIIPSAKSILLGCFFLVAQSISIFLSYNVTGDNQQTTGIVRSYIFLFGWILTVYLAWAIITVSVTNHSEEKLFINSGLVSLTIYIVLVLFPQLLVSIGQNWPLSYVNTIASLFERHWVGRNDFYIMGSYVATNHRLNGFEPEAAVLANLLSIIYLPILLGFAIVGKRLICVKNKIFNSKYIVWVMIFILFIFLIMAKTSTGIIELIVALLIWFGWSKKKDKIFLAIISILGLLFITLMYVAVPTIHNILDQFLFQKSGTDNRIGGTIALVLTFLSHPFFGVGYDYTGYFILKYVPEWTTHNWEYINFYSKERYPILSAGVGWFATFGLVIMLPALWMLGRIIARSIIIQNKLKGSNTEYALWNRAIQISFLAMTLLVAVSAIFAINIFLWPYLIMFFFYRQHLINQEKELAL
>NZ_CP000574.1|WP_025268263.1|1255506_1255902_-|hypothetical-protein
MKKEVNITVGIIAAVGIAFSAVSLNTSSKNTQQVSSNSEKKSDFSKNSSKSVTTANNTQLTNATDASSYDPNKTVQGVEVTQTMIDSVRNELTSAGLPADEWGPSDIKKIITESSRQNVSVVDYAKDNFHE
>NZ_CP000574.1|WP_025268264.1|1256034_1257006_-|hypothetical-protein
MLKPANLRKIASNIESESIKHYLKDLGVLSIRERELQGIERLVRHFMDEEVSLKSFYIGYSMPKISKEFDLLAFDQRHRVVNIELKSQADYDEEKIRKQLINNKYYLSQVAKDIKLFTYNLDSDIIYTLTEQDELETTDISSTHLFFASEFYRFLSTFGSIDVGNLDSLFRVSLYLVSPFRETQAFLEGDYLLTQQQQALQNNILTMSESGFYAVNVPSGNGKVLMLYDTVKKLSKNNTVLIVHVGKLNATQFSLRQNYGWKIIPIRQFMKKIKSKKLRNFDYIFIDEAQNLSIKNINTIRKYFQEHLHLAYIFLIGDKLRIK
>NZ_CP000574.1|WP_025268265.1|1257129_1258179_-|DUF916-and-DUF3324-domain-containing-protein
MIVKKVCGFSLALFIAMFSFFVCNNKSTAAEMNFSVKTVMPDNQIDKSKTYFNLKMNSGQQQDITVTLKNDTKKDITVEVGVNTAKTNSNGVVEYGKSSIKNDSSLKYNISNIVKGPSSIVIPASSSKNVVFHVTMPKESFDGILLGGLTFQQKSSEVNQNKAKKGTTVQNEYSYAVAILLKESDKVVNPNLNLLQVKPGQINYRNVVNAELQNDQSVLMSKVSVDAKIYSKNGKKPVYTSIKSDMQIAPNSHLTYPVSLNGTSMKAGDYTLKMKVTATANKQVKKWTFTKDFTIKSKQARDLNKSDVDVKANTNNSNWLYILIGAILLIVIIILVVVIILQRKKNSSQ
>NZ_CP000574.1|WP_025268266.1|1258214_1258985_-|WxL-domain-containing-protein
MINKKILGLAGLTSFGLATAPLAVVYADDSSAATLNSNAQVSFIRDETTKSVLNPSNPVNTDGSQNSVTPIDNVTKKEPNSGTSGLLTIDFASSFDFGTNIISSAKQTYYASAQSYSNKGTMTTGPNFAQVTDNRAGNEHTGWKLQVKQDDDFTAVNDANSKLTGATISISNGKVVNGNGSDKAINPVDNNSVAIGKENTTVMSANSGEGIGTWIYSMGSQDNADKSVSLTVPASSKINEDAYKTTLTWTLSDTPS
>NZ_CP000574.1|WP_025268267.1|1258977_1259376_-|hypothetical-protein
MKPKKFLQCVLSGFAIAGSMTICSLNVLGSEIESNAQVSFQMPDYIPVKQQATDQIDLSQATLVNAPVSNGEYDRQFGYVSTRKGVIPVITRLPSVGVTHIQSLSYILCSALIIIMVTISEKMRKEKGKNYD
>NZ_CP000574.1|WP_025268268.1|1259455_1260910_-|choice-of-anchor-A-family-protein
MLKKRLLFIAGILILATISLCNNNYPSRQISLSNTYQLKNTSNTYQLQKLADETSDTILPAAGSWKSDFPSVNDSNVLGIAGQFNYFAKNIDSISNNLNGNVATQNLKTSGGSQTGNSGISYLQKNIESSDNAAAFKSDTLILGSSLVYKDKIINDSRPSLNGYKLNQKPNKLRQDTQGSEYLNFDSEFARLENNSKAIANNSTTVSTGGNNNLKIDASNVKVQQGVKYVTIKATDFGSWGSLTIDGVANNERIVITIDTSGVTNFSTGWLNLNNGENKNILFNFYDVAQNSNYTGNIEWKPSSSNAINAILAPKATFTLVSSNFQGNIVASKIINRTNTNTVASYGDVPVPSETSITPTSKIISVPDVDFGSHKLGSETSLVGDWTGNFQVSGKKNTQIKINVALTQQLTSQNGSVADGIHWQLVKNDYSSGSLITTSQDFTNISARINYWIWKDDGTGNLLSDWKYNNEKSNMALTICKFLI
>NZ_CP000574.1|WP_025268269.1|1261290_1262133_-|dTDP-4-dehydrorhamnose-reductase
MKFLITGANGQLGQELQKLLRERGLDFVAFDSKQLDITNSAAVLSAFEQEQPDVVLHAAAYTKVDLAEDDGRELNWQVNVDGTKNVADAAKLYEAKLVAVSTDYVFDGTNEGEYLESDAVNPQNSYGRAKLAGELAVTESGADAYIVRTSWVFGEFGNNFVYTMQRLAATHPKLTVVNDQLGRPTWTRTLAEFMLHLVEVKAAYGIYHLSNDDIATWFDFAREILKDTDVEVAPVTSAEFPQKAYRPKHSVMSLDKAKATGFEILSWREALQSFLNSIVS
>NZ_CP000574.1|WP_025268270.1|1262182_1263220_-|dTDP-glucose-4,6-dehydratase
MTEYKNILVTGGAGFIGANFVRYIVEEHPDVFVTVLDKLTYAGNKENLAGLPEDRVKLVVGDIADAPLVDQLVSETDAVIHYAAESHNDNSLKDPSPFVQTNIIGTYTLIEAARKYNKRFHHVSTDEVYGDLPLREDLPGHGEGAGEKFTPESQYRPSSPYSSTKASSDLLVRAWVRSFGLQATISNTSNNYGPYQHIEKFIPRQVTNIISGIKPKLYGNGKNVRDWIHTYDHATAVWAILAKGKIGETYLVGADGEKDNITVLRAILKDMGKAEDDFDFVQDRSGHDLRYAIDATKIREELGWTPKYTDFETGLADTIQWYKDNQSWWQAEKDEVEAKYAQNNQ
>NZ_CP000574.1|WP_014947523.1|1263233_1263827_-|dTDP-4-keto-6-deoxy-D-glucose-epimerase
MTEEFFEKKLAAQPIAAIPGMIAFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFKEDKLQNNVSLSRKGVLRGLHAEPWDKYISVADNGRVLGSWVDLREGDSFGHVYQTVIDASKGIYVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYADPALGIEWHDVENAEVSEADKNHPLLKDVVPLTKEQL
>NZ_CP000574.1|WP_025268271.1|1263836_1264712_-|glucose-1-phosphate-thymidylyltransferase-RfbA
MKGIILAGGSGTRLYPITKATSKQLVPIYDKPMVYYPLSVLMLAGIKEILLISTPEYVGQFEELFGDGHEIGLNIEYAIQEEPRGLADAFIVGADFIGDDAVALVLGDNIFYGAGLSQKLQQEALKTSGATVFGYQVKDPERFGVVEFDKDGKALSIVEKPEQPKSNYAVTGLYFYDNDVVEIAANVKPSERGEIEISDINQAYLDRGDLDVQVMGRGYAWLDTGTLDSLLEASSFIATIQKQQNLKVASLEEIAYRMGYIDIAQLEKLAQPLKKNDYGQYLLRIVDEEGE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

57808 : 74862

Bacillus_virus(33.33%)

bacteriocin,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111303334.1\|57808_57979_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_011679054.1\|58150_58348_+	hypothetical protein	NA	NA	NA	NA
WP_111303610.1\|59336_59717_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_011679055.1\|59894_61451_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.3e-14	24.9
WP_025267651.1\|61450_62572_+	ABC transporter permease	NA	NA	NA	NA
WP_025267652.1\|62573_63530_+	ABC transporter permease	NA	NA	NA	NA
WP_025267653.1\|63569_64484_-	L-2-hydroxyisocaproate dehydrogenase	NA	NA	NA	NA
WP_014324152.1\|64599_65355_-	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.4e-12	29.8
WP_002815468.1\|65347_66247_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_011679060.1\|66243_67248_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002815470.1\|67714_68302_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002815471.1\|68359_69097_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_025267654.1\|70152_71502_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_038534111.1\|71519_73667_-	peptide cleavage/export ABC transporter	F2Y352	Organic_Lake_phycodnavirus	2.9e-23	30.9
WP_010287032.1\|73897_74074_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_010287029.1\|74104_74266_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_025267656.1\|74262_74568_+	hypothetical protein	NA	NA	NA	NA
WP_071951754.1\|74724_74862_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA

DBSCAN-SWA_2

545404 : 558569

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011679402.1\|545404_546670_+	insulinase family protein	A0A1X9I714	Streptococcus_phage	3.8e-47	30.8
WP_014324423.1\|546671_547943_+	insulinase family protein	A0A167R9K4	Powai_lake_megavirus	1.9e-17	31.8
WP_014324424.1\|547957_548833_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_010285285.1\|548843_549425_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_011679405.1\|549564_550722_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.1e-117	65.1
WP_011679406.1\|550804_551497_+	response regulator transcription factor	W8CYM9	Bacillus_phage	4.8e-36	34.5
WP_025267870.1\|551736_552645_+	phosphate ABC transporter substrate-binding protein	M1U9L0	Synechococcus_phage	9.2e-11	28.2
WP_025267871.1\|552728_554069_+	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	1.0e-29	35.2
WP_014324427.1\|554210_555092_+	phosphate ABC transporter substrate-binding protein PstS family protein	H6WG65	Cyanophage	7.6e-10	28.4
WP_011679411.1\|555144_556068_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_010291776.1\|556067_556952_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_011679412.1\|556959_557802_+	phosphate ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.0e-11	28.4
WP_011679413.1\|557798_558569_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.5e-17	29.7

DBSCAN-SWA_3

799849 : 808507

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025267982.1\|799849_800755_+	cation transporter	M1Q1N9	Streptococcus_phage	8.2e-44	35.6
WP_025267983.1\|800774_801734_+	arginine deiminase	NA	NA	NA	NA
WP_025267984.1\|802115_803150_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	8.5e-37	33.3
WP_011679597.1\|803149_803740_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.4e-23	34.9
WP_014324575.1\|803742_804936_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	4.5e-90	44.9
WP_011679599.1\|804960_805431_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.4e-31	43.9
WP_025267985.1\|805867_808507_+	cation-translocating P-type ATPase	M1HX51	Paramecium_bursaria_Chlorella_virus	1.5e-77	28.7

DBSCAN-SWA_4

1476624 : 1518432

Lactobacillus_phage(42.42%)

capsid,head,terminase,portal,holin,tail,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025268387.1\|1476624_1477176_-	TIGR00730 family Rossman fold protein	A0A1G5S9X4	Enterococcus_phage	1.7e-23	36.0
WP_025268388.1\|1477313_1477526_+	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_011680268.1\|1477525_1479208_+	ribonuclease J	S0A5H7	Cellulophaga_phage	2.2e-05	30.6
WP_025268389.1\|1479769_1480027_-	hypothetical protein	NA	NA	NA	NA
WP_025268390.1\|1480120_1480594_-\|holin	holin	E3W8H7	Leuconostoc_phage	2.6e-25	64.6
WP_025268391.1\|1480603_1481695_-	1,4-beta-N-acetylmuramidase	E3W8H6	Leuconostoc_phage	1.4e-191	91.7
WP_025268392.1\|1481698_1481923_-	hypothetical protein	NA	NA	NA	NA
WP_025268393.1\|1481966_1482746_-	hypothetical protein	Q5K5I3	Oenococcus_phage	2.1e-43	45.6
WP_025268394.1\|1482757_1483849_-	hypothetical protein	Q5K5I4	Oenococcus_phage	7.7e-121	59.0
WP_010284188.1\|1483845_1484271_-	hypothetical protein	Q5K5I5	Oenococcus_phage	7.0e-38	54.1
WP_010284206.1\|1484320_1484554_-	hypothetical protein	NA	NA	NA	NA
WP_011680276.1\|1484553_1484700_-	hypothetical protein	NA	NA	NA	NA
WP_038534138.1\|1484712_1489050_-	hypothetical protein	A0A059PAG7	Leuconostoc_phage	5.0e-38	56.1
WP_025268396.1\|1489063_1490176_-	hypothetical protein	NA	NA	NA	NA
WP_025268397.1\|1490241_1495455_-\|tail	phage tail tape measure protein	Q8LTK2	Lactococcus_phage	3.8e-218	47.2
WP_025268398.1\|1495455_1495635_-	hypothetical protein	NA	NA	NA	NA
WP_025268399.1\|1495673_1496084_-	hypothetical protein	NA	NA	NA	NA
WP_025268400.1\|1496422_1497061_-	small major structural protein	A0A2P0ZLH1	Lactobacillus_phage	5.6e-23	38.8
WP_025268401.1\|1497064_1497439_-	DUF806 family protein	A0A2P0ZLF4	Lactobacillus_phage	1.1e-13	34.9
WP_025268402.1\|1497438_1497855_-	hypothetical protein	A0A0M7RDL2	Lactobacillus_phage	3.4e-21	43.7
WP_025268403.1\|1497844_1498216_-\|head	phage head closure protein	Q8LTK7	Lactococcus_phage	3.6e-06	31.0
WP_025268404.1\|1498208_1498541_-\|head,tail	phage gp6-like head-tail connector protein	Q6J1Y1	Lactobacillus_phage	1.5e-22	53.3
WP_025268405.1\|1498551_1499715_-\|capsid	phage major capsid protein	Q6J1Y2	Lactobacillus_phage	5.7e-138	66.8
WP_025268406.1\|1499725_1500415_-\|protease	Clp protease ClpP	Q6J1Y3	Lactobacillus_phage	5.8e-58	51.3
WP_025268407.1\|1500411_1501554_-\|portal	phage portal protein	Q6J1Y4	Lactobacillus_phage	6.6e-99	51.9
WP_025268408.1\|1501558_1501747_-	hypothetical protein	A8YQI9	Lactobacillus_phage	2.6e-05	51.9
WP_025268409.1\|1501743_1503624_-\|terminase	terminase large subunit	A8YQI8	Lactobacillus_phage	8.6e-237	63.7
WP_025268410.1\|1503610_1504174_-\|terminase	phage terminase small subunit P27 family	B8R648	Lactobacillus_phage	3.8e-15	34.8
WP_025268411.1\|1504709_1505240_-	HNH endonuclease	A8YQN7	Lactobacillus_phage	2.9e-41	47.5
WP_025268412.1\|1505239_1505434_-	hypothetical protein	NA	NA	NA	NA
WP_025268413.1\|1505499_1505700_-	hypothetical protein	A0A097BY73	Enterococcus_phage	7.2e-17	68.2
WP_025268414.1\|1505820_1506390_-	hypothetical protein	NA	NA	NA	NA
WP_025268415.1\|1506451_1506760_-	hypothetical protein	NA	NA	NA	NA
WP_025268416.1\|1506807_1507005_-	hypothetical protein	NA	NA	NA	NA
WP_011680294.1\|1507065_1507320_-	hypothetical protein	NA	NA	NA	NA
WP_010292081.1\|1507855_1508434_-	hypothetical protein	NA	NA	NA	NA
WP_025268417.1\|1508531_1508975_-	DUF722 domain-containing protein	E3W8E2	Leuconostoc_phage	4.2e-09	31.7
WP_025268418.1\|1509399_1509840_-	hypothetical protein	NA	NA	NA	NA
WP_025268419.1\|1509842_1510241_-	hypothetical protein	A0A0P0IJF8	Lactobacillus_phage	4.3e-21	48.7
WP_025268420.1\|1510233_1510455_-	hypothetical protein	A0A097BYE4	Leuconostoc_phage	6.3e-14	62.5
WP_025268421.1\|1511064_1511838_-	AAA family ATPase	E9LUM7	Lactobacillus_phage	1.3e-37	37.8
WP_025268422.1\|1511834_1512593_-	DNA replication protein	A0A1P8VVR3	Streptococcus_phage	1.4e-65	56.7
WP_025268423.1\|1512603_1513029_-	single-stranded DNA-binding protein	A0A097BYB0	Leuconostoc_phage	1.2e-53	75.9
WP_025268424.1\|1512994_1513645_-	ERF family protein	Q9G0C9	Lactococcus_phage	2.9e-14	38.2
WP_025268425.1\|1513644_1514544_-	DUF1351 domain-containing protein	NA	NA	NA	NA
WP_025268426.1\|1514546_1514729_-	hypothetical protein	NA	NA	NA	NA
WP_025268427.1\|1514821_1515028_-	helix-turn-helix transcriptional regulator	M1PKR2	Streptococcus_phage	3.8e-05	46.0
WP_025268428.1\|1515153_1515384_+	hypothetical protein	NA	NA	NA	NA
WP_155246465.1\|1515364_1515526_-	hypothetical protein	NA	NA	NA	NA
WP_051394935.1\|1515714_1516533_-	phage antirepressor KilAC domain-containing protein	A0A0A7DN31	Lactobacillus_phage	1.6e-75	64.4
WP_025268430.1\|1516496_1516739_-	hypothetical protein	NA	NA	NA	NA
WP_010284703.1\|1516807_1517017_+	hypothetical protein	NA	NA	NA	NA
WP_155246466.1\|1516994_1517141_-	hypothetical protein	NA	NA	NA	NA
WP_025268431.1\|1517157_1517388_-	hypothetical protein	NA	NA	NA	NA
WP_025268432.1\|1517653_1518001_+	transcriptional regulator	E3W8B9	Leuconostoc_phage	1.2e-24	53.8
WP_025268433.1\|1517997_1518432_+	hypothetical protein	E3W8B8	Leuconostoc_phage	4.0e-73	93.8

DBSCAN-SWA_5

1635006 : 1645778

Pandoravirus(14.29%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025268486.1\|1635006_1636116_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A0B5JD48	Pandoravirus	2.4e-13	27.5
WP_025268487.1\|1636112_1637030_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_002815833.1\|1637538_1637865_+	thioredoxin family protein	NA	NA	NA	NA
WP_025268488.1\|1637958_1638816_-\|protease	trypsin-like serine protease	W5SAB9	Pithovirus	4.3e-10	29.3
WP_025268489.1\|1638907_1640206_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	2.6e-14	26.5
WP_011680398.1\|1640186_1640888_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.0e-30	35.4
WP_002815839.1\|1640968_1641334_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A2P0ZKX3	Lactobacillus_phage	9.4e-07	36.8
WP_014325120.1\|1641372_1642494_-	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	3.8e-30	29.5
WP_002815841.1\|1642490_1642901_-	holo-ACP synthase	NA	NA	NA	NA
WP_011680400.1\|1642971_1644258_-	D-alanyl-lipoteichoic acid biosynthesis protein DltD	NA	NA	NA	NA
WP_010292689.1\|1644262_1644499_-	D-alanine--poly(phosphoribitol) ligase subunit DltC	NA	NA	NA	NA
WP_025268491.1\|1644569_1645778_-	D-alanyl-lipoteichoic acid biosynthesis protein DltB	A0A125RNP0	Pseudomonas_phage	1.9e-19	26.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP000574

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection