CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP006850	Nocardia nova SH22a chromosome, complete genome	18 crisprs	csa3,WYL,DinG,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,DEDDh,RT,cas4	0	14	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP006850_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_1

632199-632295

Orphan

Consensus_repeat	Method
GGGTGCCGGATTCTCCTGCACCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_1

>merge|NZ_CP006850|1|632199-632295|CRISPRCasFinder
GGGTGCCGGATTCTCCTGCACCCCTGGCCAGGCGTCCCTGGCCGCAGCGTGCTCGAACACGGTGTCAGCGGCCGGGTGCCGGATTCTCCTGCATCCC

>NZ_CP006850|1|1|632199-632295|CRISPRCasFinder
GGGTGCCGGATTCTCCTGCACCCC	TGGCCAGGCGTCCCTGGCCGCAGCGTGCTCGAACACGGTGTCAGCGGCC
GGGTGCCGGATTCTCCTGCATCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025346918.1\|622680_623850_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|235596
NZ_CP006850.1\|WP_025346921.1\|626389_626860_+\|HIT-family-protein	unknown	unknown	gnl\|CDD\|238608
NZ_CP006850.1\|WP_148306699.1\|628501_628711_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025346933.1\|637949_638186_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl\|CDD\|235659
NZ_CP006850.1\|WP_025346935.1\|639030_639465_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP006850.1\|WP_025346929.1\|633915_635346_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|163525
NZ_CP006850.1\|WP_025346936.1\|639512_640802_+\|M18-family-aminopeptidase	unknown	unknown	gnl\|CDD\|235073
NZ_CP006850.1\|WP_025346922.1\|626966_627926_+\|esterase-family-protein	unknown	unknown	gnl\|CDD\|223700
NZ_CP006850.1\|WP_081769618.1\|640759_642319_-\|DUF2029-domain-containing-protein	unknown	unknown	gnl\|CDD\|172015
NZ_CP006850.1\|WP_025346931.1\|635816_637187_+\|dipeptidase	unknown	unknown	gnl\|CDD\|236127
NZ_CP006850.1\|WP_038551727.1\|631422_632142_+\|DUF2334-domain-containing-protein	unknown	unknown	gnl\|CDD\|225773
NZ_CP006850.1\|WP_025346919.1\|624152_624833_+\|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|225767
NZ_CP006850.1\|WP_148306700.1\|631040_631337_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025346938.1\|642209_644504_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NZ_CP006850.1\|WP_025346920.1\|624839_626273_+\|adenylosuccinate-lyase	unknown	unknown	gnl\|CDD\|176471
NZ_CP006850.1\|WP_081769617.1\|627963_628311_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP006850.1\|WP_025346925.1\|628808_630950_+\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224684
NZ_CP006850.1\|WP_025346930.1\|635342_635804_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025346932.1\|637191_637836_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|316044
NZ_CP006850.1\|WP_025346934.1\|638182_638863_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl\|CDD\|235140

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025346938.1\|642209_644504_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP006850.1\|WP_025346921.1\|626389_626860_+\|HIT-family-protein	gnl\|CDD\|238608	cd01277, HINT_subgroup, HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life. Although the biochemical function has not been characterised for many of the members of this subgroup, the proteins from Yeast have been shown to be involved in secretion, peroxisome formation and gene expression.	3.07794e-43
NZ_CP006850.1\|WP_025346935.1\|639030_639465_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.23944e-16
NZ_CP006850.1\|WP_025346933.1\|637949_638186_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl\|CDD\|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	8.69203e-36
NZ_CP006850.1\|WP_025346929.1\|633915_635346_+\|amino-acid-permease	gnl\|CDD\|163525	TIGR03813, put_Glu_GABA_T, putative glutamate/gamma-aminobutyrate antiporter. Members of this protein family are putative putative glutamate/gamma-aminobutyrate antiporters. Each member of the seed alignment is found adjacent to a glutamate decarboxylase, which converts glutamate (Glu) to gamma-aminobutyrate (GABA). However, the majority belong to genome contexts with a glutaminase (converts Gln to Glu) as well as the decarboxylase that converts Glu to GABA. The specificity of the transporter remains uncertain.	3.27447e-117
NZ_CP006850.1\|WP_025346936.1\|639512_640802_+\|M18-family-aminopeptidase	gnl\|CDD\|235073	PRK02813, PRK02813, putative aminopeptidase 2; Provisional.	0
NZ_CP006850.1\|WP_025346922.1\|626966_627926_+\|esterase-family-protein	gnl\|CDD\|223700	COG0627, COG0627, Predicted esterase [General function prediction only].	3.51432e-53
NZ_CP006850.1\|WP_081769618.1\|640759_642319_-\|DUF2029-domain-containing-protein	gnl\|CDD\|172015	PRK13375, pimE, mannosyltransferase; Provisional.	1.50552e-44
NZ_CP006850.1\|WP_025346931.1\|635816_637187_+\|dipeptidase	gnl\|CDD\|236127	PRK07907, PRK07907, hypothetical protein; Provisional.	0
NZ_CP006850.1\|WP_038551727.1\|631422_632142_+\|DUF2334-domain-containing-protein	gnl\|CDD\|225773	COG3233, COG3233, Predicted deacetylase [General function prediction only].	2.49723e-61
NZ_CP006850.1\|WP_025346919.1\|624152_624833_+\|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl\|CDD\|225767	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown].	1.01394e-23
NZ_CP006850.1\|WP_081769617.1\|627963_628311_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.80386e-16
NZ_CP006850.1\|WP_025346920.1\|624839_626273_+\|adenylosuccinate-lyase	gnl\|CDD\|176471	cd03302, Adenylsuccinate_lyase_2, Adenylsuccinate lyase (ASL)_subgroup 2. This subgroup contains mainly eukaryotic proteins similar to ASL, a member of the Lyase class I family. Members of this family for the most part catalyze similar beta-elimination reactions in which a C-N or C-O bond is cleaved with the release of fumarate as one of the products. These proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits. ASL catalyzes two steps in the de novo purine biosynthesis: the conversion of 5-aminoimidazole-(N-succinylocarboxamide) ribotide (SAICAR) into 5-aminoimidazole-4-carboxamide ribotide (AICAR) and, the conversion of adenylsuccinate (SAMP) into adenosine monophosphate (AMP). ASL deficiency has been linked to several pathologies including psychomotor retardation with autistic features, epilepsy and muscle wasting.	0
NZ_CP006850.1\|WP_025346918.1\|622680_623850_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	1.38839e-154
NZ_CP006850.1\|WP_025346925.1\|628808_630950_+\|S9-family-peptidase	gnl\|CDD\|224684	COG1770, PtrB, Protease II [Amino acid transport and metabolism].	0
NZ_CP006850.1\|WP_025346932.1\|637191_637836_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|316044	pfam13483, Lactamase_B_3, Beta-lactamase superfamily domain. This family is part of the beta-lactamase superfamily and is related to pfam00753.	1.21419e-15
NZ_CP006850.1\|WP_025346934.1\|638182_638863_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	4.24022e-145

>NZ_CP006850.1|WP_038551727.1|631422_632142_+|DUF2334-domain-containing-protein
MTGNDRGFGQLIVSVSGIRDTTLEQASAFAAEMDSRGVRLSLLVAPRLKGKYRLTEDAHTQEWLRERRASGDAIVLHGYDQAATKRRRAEFATLPKHEARLRLTAADRVMEEIGLRTRLFAAPRWTISDGALAALPEVGFRLALGLTTVHDLERDVAQRCWVHGMGEGFRAEPWWCHALVMSAARIARRGGTLRLAVSAAQLSRPGPHQAMLDAVDLALFHEAAPQVYRWEPFILPHAA
>NZ_CP006850.1|WP_148306700.1|631040_631337_-|hypothetical-protein
MRAAILTALAVPLMIAAPGLAQADPGDPPPIYTQDEQCATTKDFVDKVHQANPGATPDQIADTYTRIMDEHNAYRGNEDARQRDRQYLLDNISRCGLA
>NZ_CP006850.1|WP_025346925.1|628808_630950_+|S9-family-peptidase
MALETAAAVIPPIAKKVPTERTHHGDTFADPYEWLRDKDDPEVIAYLEAENAYTDAQTAQLAPLRARIFDEIKSRTQETDLSVPSRLGDYWYYSRSFEGKQYGVHCRCPIADRDDWTPPQLDVDTEITGEEILLDSNVLAAGHDFFALGAYSISHDGTLLAYSTDTVGDERYVLRFKDLRTGELLGDEIAGTAPGATWSLDGTHVFYQTVDESWRPDTVWRHRLGADRSGDVRVFHEPDERYWVSIGATRSEKYLMIWVGSKITSEGWILESDDPEGEFRVLLPRREGVEYSAEHAVIGGHDRLLILHNDVIDGVKAENFVLAEAPVDDPAAMTTLIGHRDEVRLEDIDCFADHLVLSYRREALPRVAVWPLTSDGYGELRELDFGLELFSAGVGSNPEWAQPTLRLGVTSFITPMQIFDYVPATGEMTLRKQQQVLGGYDPDDYVQHRDWAVAADGTRIPVSVVRRRDSEGSGPKPLLLYGYGSYEASIDPGFSVSRLSLLDRGMVFAVAHVRGGGEMGRLWYEHGKTLTKKNTFTDFVSCARHLVDTEVTRPELMVADGGSAGGLLMGAVANLAPELFTGILANVPFVDPLTSILDPSLPLTVIEWDEWGNPLEDPEVYAYMKSYSPYENVTAQNYPAILAITSINDTRVLYVEPAKWVAALRATKTGDSQLLLKTEMSAGHGGVSGRYEKWKEVAFEYAWVLDTVGLGES
>NZ_CP006850.1|WP_148306699.1|628501_628711_+|hypothetical-protein
MAPVFDSCAVVPRHLTVEQAHNILHSHSSCPTDQCPRRKAALFFLMESRRSARGTGTDLRRSAPRTGLG
>NZ_CP006850.1|WP_081769617.1|627963_628311_-|DUF397-domain-containing-protein
MSPAGGFAGRRRRPARRPPTVYEDGAHPVRRWAITSIREHRLEAKNRDIEPGAVWQRSGDGAGGVEVAFLASGNIGLRDAKNPDGPALIFTPGEWRAFVAGAKDGEFNRPGAESA
>NZ_CP006850.1|WP_025346922.1|626966_627926_+|esterase-family-protein
MRRSTVAAFVLAVVAGVLGPWSGPQPRAAAAQVVGENDMSATRTALFIDSPAMGRTIQVQVLHPAGGGARPSYYLLDGLDPGVQQSTWTNATDAEPFFAGKNVNVVLPMGGQASYYTDWQSDDPHFGRYRWETFLTQELPPIIDATFDGNGVNAIGGLSMGGIAAFVLAARHPELYDAIAGYSACPDLGLAQGAITFSIANRGGNPFNMWGAPGSPEWGAHDPALLVNRLRGKTIYLSTGTGIPGPHEAEIKPQLPENIFLGGPIEAGVDVCVTAFEQRLRGMRIPARVDHNPVGTHSWSYWQDYLHASWPTIGAAIGA
>NZ_CP006850.1|WP_025346921.1|626389_626860_+|HIT-family-protein
MDPYSIFADIVAGRAPSSKVYEDADVLAFMDIRPMTPGHLLVIPKVPARSLAELDPAIGGKLFQVGQRLAAALRESEVRCDGVNLFLADGVTAGQEIFHVHLHVIPRTPGDGFGLRNRATTPPRADLDYLAASIRGAAQRLGSAAEARPDGTWWLT
>NZ_CP006850.1|WP_025346920.1|624839_626273_+|adenylosuccinate-lyase
MTLVPNVLATRYASPQLVQLWSPENKIVLERRLWLEVLRAQTELGAAGTESVTPEVIEDYERVLGEVDLASIAERERITRHDVKARIEEYNALAGHEQIHKGMTSRDLTENVEQLQIRLSLEHVHEHGVAVAARLAERAAEYQALVMAGRSHNVAAQATTLGKRFASAADEILIALRRVRELIDRYPLRGIKGPMGTAQDMLDLFDGDAGKLAQLEQKVARHLGFSTVLTSVGQVYPRSLDHDVVSALVQLGAGPSSLAHTVRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLQVVLRGYGSMAAELSGAQWNEGDVFCSVVRRVALPDAFFAIDGMMETFLTVLTEFGAYPAVIERELNRYLPFLATTRILMAAVRAGVGRESAHEVIKEHAVAVALAMREQGREPDLLDRLAADDRMPLDRAGLEAALADRTAFIGAAEAQVGDVVAQVQKLIDAHPEAARYTPSPIL
>NZ_CP006850.1|WP_025346919.1|624152_624833_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MITATTPKGERRRQALVAAAAELLLEGGFDAVRHRSVATRADLPLASTTYYFESLEDLIARAVEFSGTAELEAMRRRIGDVTHRRRGPEATVDLIVDLMVGTDGPDDFARGRLIARYERSVASARHPELREVQLRLRAQLEDLVADVLRRSDRTVRTDQLRRLVAVVDGAVVAALAESDPQPRRTARAALLELIDVIAPPTPQSLLASQPMPPAMPQQPSRHRTLD
>NZ_CP006850.1|WP_025346918.1|622680_623850_+|pyridoxal-phosphate-dependent-aminotransferase
MRSESRRSTVPTFYVMDVWKAAAERARTHGDVLVLAAGQPSTPAPAPVLRATRAALDGELLGYTETFGIPELREAIAAHHRDGYGVDAVADDVVVTTGSSGAFTLLFLAAFDIGDTVVVARPGYPAYRNTLTALGCRVIELDCGPQTRFQPTVAMLEELPEPPAGLIVASPANPTGTMIAPDELAALARWCDDHGTLLISDEIYHGIAYSGSGGDTEPVSSAWETSRESVVIGSVSKYFSMTGWRLGWMLAPERLRPALQRLASNMTVCPPAISQFAAVHAFGAEAKTELDGHVRRYARNRALLLDGLPRLGITDLAPADGAFYAYADIGHLSQDSTRWCADLLARTGVALAPGIDFDTSNGHRTVRFSFAGATADIEEALVRLGRYLS
>NZ_CP006850.1|WP_025346929.1|633915_635346_+|amino-acid-permease
MTDTVTAARKPLVTKYISWVTLALMTTSSVASLRSAPTMAVYGLACVFLYVVPALLFLLPTAFVSAELASGWDGGVYKWVGEGLSKQLGFLAVWCQFAMTIFYYPSLLAYVASTFAYIINPSLASNGPYVAIVIIVIYWAGVFVSAQGTKTVAGLSSMGLVIGTLIPGALLVVLGIVFLAQGNSSAAPMDAGHLLPQWTGLASLVLIVNNFLSYAGMEMNAVHVSSLRNPAREYPRAMALAVGLVLAIFIVPAVVISWVVPSQSLSLTAGVMQAFDGFFNHFGIGFLTPVLGIMLVAAALGGMLTWLAGPSKGLLLIGRSEGYLPPVLTRVNKHGVQQNMLVAQGIFTTVLALLYAFIPNVSSAYWMLSVITTQVYLIMYVLLFAAAVQLRRRQPGHPRGYRAPWLIGLCGLGSASSVAAFLIGFVPPSQYGSGGAWRYVLVVGLGMGVVGLLIPYLFLRLRRPEWKTEVPAEALS
>NZ_CP006850.1|WP_025346930.1|635342_635804_+|hypothetical-protein
MTGPAASHPVETAEQTRNRRFVNVIVVVVLVALAIVGLLVFEQKRDDARAAELAQVLHDRLVAAGLPAPEPDRIADTLGDDGGLICSDPSSPLVAARYRDAIATGAAGPGNRPVILDRDVLAATEIAVRTYCPDHLPAYLDRVARLRLGDTAK
>NZ_CP006850.1|WP_025346931.1|635816_637187_+|dipeptidase
MTDDARTAELRAQVRSLMPQAKSDLAQLVSYRSVADARQFPPEECHRAAQWVVDAFAGLGLSDAGLHETPDGSNAVVARYPAPAGAPTVLLYCHYDVQPPLDDAAWHSPVWELTERDGRWYGRGAADCKGNIVTHLTALRALRNTLDGKGYPVGITLVAEGSEEQGTGGLDAFVPEHADLLRADALVIADCGNFAVGVPTFTQTLRGNVNVLVTVETLSGSLHSGMFGGAAPDAVAALVHLLATLRDEAGNTTVAGLTADQVWDGVQYPAEQFRADAGVLDGVELLGSGTVSDMLWARPALTVLGIDVPPVVGSAAAIQPSARARLNLRIPPGTDPDSALKALTAHLESHVPWGARLHIETEGTGSPFRSGTGGPARRAMEDAFATAYGRTATTQGQGGSIPLCNVFADTYPDAEIMLIGVEEPKCLIHAPNESVDPDEIEQLALTEALFLQSYTR
>NZ_CP006850.1|WP_025346932.1|637191_637836_-|MBL-fold-metallo-hydrolase
MRIAHFGHSCVLVEFDGVKILFDPGTFSHGFEGITGLDAIAITHQHPDHIDPNRIEALIDANPSARLLSDPQTAQQRGESWEAVHAGNIVNIGDLQITGGGGKHAVIHPELPVVDNTVFQLGTPDDPAQFVHPGDSLWVPPVSVGVLAVPAAAPWMKISEAVDYLRAVSPRTAVPIHYGIIEPQAQGIYFGRLSEMRPADTEFTLIEPEDHAEF
>NZ_CP006850.1|WP_025346933.1|637949_638186_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MARVVVEVMPKAEILDPQGQAIVGALGRLGFPGVSDVRQGKRFELDIDGSVSDAELEKIAEGLLANTVIEDWKVVRLP
>NZ_CP006850.1|WP_025346934.1|638182_638863_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MSTARIGVITFPGTLDDVDAARAVRLSGAEAVSLWHADADLKGVDAVIVPGGFSYGDYLRAGAIARFAPVMGKVVEAAGKGMPVLGICNGFQVLCEAGLLPGALTRNEGLHFVCRDQWLRVESTATAWSSRYDADAQILIPVKNAEGRYQASDAVLDELEGEGRVVFRYAGGNPNGSQRDIAGIASANGRVVGLMPHPEHATEPLTGPSDDGLGMFLSVLDSLVAA
>NZ_CP006850.1|WP_025346935.1|639030_639465_+|MarR-family-transcriptional-regulator
MSTMVSGVATLHGALRAAERGWLRHLDTALCARQLTADQWAMLSNLSDSSGITMSELAVRSQLAPSSATRHADALAERGLIFRIAAEDDRRRILIGLTHRGKDLVDSVREQEALAEEELRKRIGSRNHAELLRLLELMNETPAE
>NZ_CP006850.1|WP_025346936.1|639512_640802_+|M18-family-aminopeptidase
MSVPTTATASGLCAFVDSSPSPFHVCRTAAAELAAHGFTELPETRPWTRTEAIGRYFVIRGGSLVAWVSGKRNPAGAFRVVGAHTDSPNLRVKQHPDLAVAGWQLIGLEPYGGAWLNSWLDRDLGISGRLTVRAGDGLGERLVRIDDPLVRVPQLAIHLSEDRRGVTLDPQRHVNGIWGLGERPRSFITYVAEWAGVPVDDVLGWELMTHDLEPSRLVGRDQDLVSAPRLDNQATCYAGLRAFLAAADTAGDTTPVLAMFDHEEVGSQSDRGAQSDLLPAILERIVLARGGGRADYLAALAGSICASGDMAHATHPNYPERHEPAHRIEVGGGPVLKVNQNLRYATDAVGAGAFALACAQAGVPLQRYVHRADLPCGSTIGPMTAARTGMPTVDVGAPQLAMHSARELMGADDVGAYAAALAAFLAPGR
>NZ_CP006850.1|WP_081769618.1|640759_642319_-|DUF2029-domain-containing-protein
MSRIRAYSSSLRPSSLYGCGVSGVAAAALTVSTWTVTVGTKVLSAGQTCSYDLRRWSVRRNAGGWKSRSVYAGRTRPDQAAPFHRYAEPVNDRSRVADPDELPVTATAERSSGTLTTRRRRLLMIAIALFVVSAIVSLISHTWGGFIDLQVYRNGARTWLDGGDLYGPMPPVGGIGLPFTYPPLAALFFAPLALMPLIPAQCLVLITSMAALAVTMWLVLDRIRPDMDRTTRLILLIGALAVLGLSEPVRQTYNFGQINLILMVAVALDALVRKPFWPRGMLIGITVSVKLIPGGYLLYFLLRRDWRACATLIGSAVGAIAVGFLLFPSDSTEYWFHTLADTGRIGPPQYAGNQSLKGFAFRLGVSDSAATVIWILLSLIAIGLAALWMKRLLDNGHNVSALLVNSAAVLLVSPVSWSHHWVWIAPALLVAGDLIARMPTGDSTSLRKRRLWIALTTALTVMFMVGPQWLLPHNADRELRWSWWEQIIGSSYVLVAFAALVIAAIAYRPGARKAASAAA
>NZ_CP006850.1|WP_025346938.1|642209_644504_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MTVHVDTVSAAAATPDTPQPYKELGLKDDEYARIRDILGRRPTDAELAMYSVMWSEHCSYKSSKVHLRYFGETTTDEMRAAMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPIAVMDQLRFGAADHPDTRRVVDGVVRGVGGYGNSLGLPNVGGETVFDPSYQGNPLVNALCAGVMRVEDLHLAFASGTGNKIVLFGARTGLDGIGGVSVLASDTFSGDESGSGRKKLPSVQVGDPFAEKVLIECCLELYHAGLVVGIQDLGGAGLSCATSELAAAGDGGMRIDLDRVPLRAANMTPAEILSSESQERMCAVVTPENVDAFMDVCRKWDVLATVIGEVTDGERLVVNWHGETVVDVPPRTVAHEGPVYERPVQRPEEQDALVADTTAGLNRPKSGDELRVAALKLISSPQLCSRKWIVEQYDRYVRGNTVLAENADAGVIRIDETSGRGISLATDASGRYTKLDPYAGAQLALAEAYRNVASTGATPKAVTNCLNFGSPEDPGVMWQFQQAVRGLADGCVALGIPVTGGNVSFYNQTGQTAILPTPVVGVLGVIDDVHRRIPTGLGSEPGETLILLGETRDEFDGSIWSQVEHDHLGGVPPRVDFAREQLLAEVLTAGSRDGMISAAHDLSEGGLIQAVVEAALAGETGCRILLPEDADPFVTLFSESAGRVLVAVPRSEETRFTKMCTARELPWVRIGVVDQGSDSVEVQGQFSVTLDELRTTHEATLPALFGTSAE

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Crispr_ID: NZ_CP006850_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_2

1026615-1026715

Orphan

Consensus_repeat	Method
GGTGGTGGGTTCCGTGATCCGTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_2

>merge|NZ_CP006850|2|1026615-1026715|CRISPRCasFinder
GGTGGTGGGTTCCGTGATCCGTCGGACCCGAATTACATGACTCCGTCGCGGCCTGCTCCCGCTCCGCCGGTGAATAGCGGTGGTGGGTTCCGTGATCCGTC

>NZ_CP006850|2|2|1026615-1026715|CRISPRCasFinder
GGTGGTGGGTTCCGTGATCCGTC	GGACCCGAATTACATGACTCCGTCGCGGCCTGCTCCCGCTCCGCCGGTGAATAGC
GGTGGTGGGTTCCGTGATCCGTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025347257.1\|1057258_1059172_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236545
NZ_CP006850.1\|WP_025347253.1\|1034199_1034520_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377587
NZ_CP006850.1\|WP_025347239.1\|1019589_1019775_+\|50S-ribosomal-protein-L30	unknown	unknown	gnl\|CDD\|180163
NZ_CP006850.1\|WP_025347252.1\|1033605_1034046_-\|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl\|CDD\|235383
NZ_CP006850.1\|WP_025347249.1\|1028110_1031107_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375063
NZ_CP006850.1\|WP_025347254.1\|1034516_1035017_+\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|376829
NZ_CP006850.1\|WP_025347248.1\|1027775_1028108_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347243.1\|1022287_1023088_+\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_CP006850.1\|WP_025347258.1\|1059168_1059981_+\|ESX-secretion-associated-protein-EspG	unknown	unknown	gnl\|CDD\|379414
NZ_CP006850.1\|WP_051494940.1\|1055707_1057093_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347238.1\|1018952_1019588_+\|30S-ribosomal-protein-S5	unknown	unknown	gnl\|CDD\|234790
NZ_CP006850.1\|WP_025347244.1\|1023151_1023349_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347250.1\|1031103_1031895_+\|ESX-secretion-associated-protein-EspG	unknown	unknown	gnl\|CDD\|379414
NZ_CP006850.1\|WP_025347240.1\|1019771_1020218_+\|50S-ribosomal-protein-L15	unknown	unknown	gnl\|CDD\|235523
NZ_CP006850.1\|WP_025347242.1\|1021736_1022282_+\|adenylate-kinase	unknown	unknown	gnl\|CDD\|234711
NZ_CP006850.1\|WP_025347237.1\|1018495_1018903_+\|50S-ribosomal-protein-L18	unknown	unknown	gnl\|CDD\|235524
NZ_CP006850.1\|WP_025347241.1\|1020417_1021740_+\|preprotein-translocase-subunit-SecY	unknown	unknown	gnl\|CDD\|236412
NZ_CP006850.1\|WP_025347245.1\|1023587_1024376_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_051494615.1\|1024466_1024982_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347255.1\|1035033_1055124_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025347257.1\|1057258_1059172_+\|hypothetical-protein	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.38133e-11
NZ_CP006850.1\|WP_025347253.1\|1034199_1034520_+\|hypothetical-protein	gnl\|CDD\|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	0.00232838
NZ_CP006850.1\|WP_025347239.1\|1019589_1019775_+\|50S-ribosomal-protein-L30	gnl\|CDD\|180163	PRK05611, rpmD, 50S ribosomal protein L30; Reviewed.	3.18174e-26
NZ_CP006850.1\|WP_025347252.1\|1033605_1034046_-\|D-tyrosyl-tRNA(Tyr)-deacylase	gnl\|CDD\|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	1.29643e-83
NZ_CP006850.1\|WP_025347240.1\|1019771_1020218_+\|50S-ribosomal-protein-L15	gnl\|CDD\|235523	PRK05592, rplO, 50S ribosomal protein L15; Reviewed.	4.24574e-65
NZ_CP006850.1\|WP_025347254.1\|1034516_1035017_+\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|376829	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family. This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure. The conformation of the DNA is changed when bound to these proteins. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage.	0.000432754
NZ_CP006850.1\|WP_025347258.1\|1059168_1059981_+\|ESX-secretion-associated-protein-EspG	gnl\|CDD\|379414	pfam14011, ESX-1_EspG, EspG family. This family of proteins contains the the EspG1, EspG2 and EspG3 proteins from M. tuberculosis. These proteins are involved in the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis which is important for virulence and intercellular spread. Proteins in this family are typically between 254 and 295 amino acids in length.	6.73758e-12
NZ_CP006850.1\|WP_025347243.1\|1022287_1023088_+\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	4.19215e-140
NZ_CP006850.1\|WP_025347238.1\|1018952_1019588_+\|30S-ribosomal-protein-S5	gnl\|CDD\|234790	PRK00550, rpsE, 30S ribosomal protein S5; Validated.	3.1408e-93
NZ_CP006850.1\|WP_025347250.1\|1031103_1031895_+\|ESX-secretion-associated-protein-EspG	gnl\|CDD\|379414	pfam14011, ESX-1_EspG, EspG family. This family of proteins contains the the EspG1, EspG2 and EspG3 proteins from M. tuberculosis. These proteins are involved in the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis which is important for virulence and intercellular spread. Proteins in this family are typically between 254 and 295 amino acids in length.	6.18107e-12
NZ_CP006850.1\|WP_025347249.1\|1028110_1031107_+\|hypothetical-protein	gnl\|CDD\|375063	pfam17228, SGP, Sulphur globule protein. Sulphur globules are membrane-bounded intracellular globules, used by purple sulphur bacteria to transiently store sulphur during the oxidisation of reduced sulphur compounds. This proteobacterial family contains structural proteins of these sulphur globules, and includes sulphur globule protein CV1 (SgpA) and sulphur globule protein CV2 (SgpB).	6.852e-06
NZ_CP006850.1\|WP_025347242.1\|1021736_1022282_+\|adenylate-kinase	gnl\|CDD\|234711	PRK00279, adk, adenylate kinase; Reviewed.	2.34605e-100
NZ_CP006850.1\|WP_025347237.1\|1018495_1018903_+\|50S-ribosomal-protein-L18	gnl\|CDD\|235524	PRK05593, rplR, 50S ribosomal protein L18; Reviewed.	2.45062e-54
NZ_CP006850.1\|WP_025347241.1\|1020417_1021740_+\|preprotein-translocase-subunit-SecY	gnl\|CDD\|236412	PRK09204, secY, preprotein translocase subunit SecY; Reviewed.	0
NZ_CP006850.1\|WP_025347255.1\|1035033_1055124_+\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	6.60476e-15

>NZ_CP006850.1|WP_051494615.1|1024466_1024982_+|hypothetical-protein
MLSYPMRGSTAEVTVVNERLQADMMTVLEGLDEQLRGIAEIQLRRSRLTATARTCEQRIEVTVNADGLLIETKFADDIADLTYDEIAAGMTAAVQQAAAEVLRLGSELMQPLRERKLQLPKLSEIIEGAPDLGEMMPTAPPVPKRPEDYHEGRPGGPADGSVRRSMVSDED
>NZ_CP006850.1|WP_025347245.1|1023587_1024376_+|hypothetical-protein
MANQDDPAVSAAVADAAARTGLGRHRITYYPIPPANGGYIVLMVLAIAGVIGAVISFAVKQPVVGILCCVLPIVLVPMMIRSRSYWSKYDGARLDLFDAGLVMVRPERLWVARYDSTTVYQDIVTHVRTNGPRYTTYVYTFTDIAGVNFVIGQGISGPKEWGLAIQRAVAEAQTPQALAALQAGNRLVFGELWMTWHEVGSTRNSAPWTQVNQVSIQDGRLSVDVAGRWFALTSALVRDIPNFLVFKALAEHMRRVHGSLPR
>NZ_CP006850.1|WP_025347244.1|1023151_1023349_-|hypothetical-protein
MTHRRTTLTPGTHEVLDYFGKCPECGYPAHASADFAGATTVIASCDRPCGWTGVVPLTTMTGRAS
>NZ_CP006850.1|WP_025347243.1|1022287_1023088_+|type-I-methionyl-aminopeptidase
MVFGLKQKKVVPFRTAGELDAMAAAGAIVGRALVAVRAAAAPGVSTLELDEVAEQTIREAGAVPSFKGYHGFPGSICSSVNDRVVHGIPSKNEVLTAGDLVSIDCGAILDGWHGDSAWTFGVGEIIEADRLLSEATRLSMDAGIAAMLPGNRLTDVSHAIELGTRAAEKEHGRAYGIVDGYGGHGIGRQMHMDPFLANEGAPGRGPKLVVGSVLAIEPMLTLGTTETVVLDDDWTVVTSDGSRAAHWEHTVAVTEDGPRILTLRPE
>NZ_CP006850.1|WP_025347242.1|1021736_1022282_+|adenylate-kinase
MRLVLLGPPGAGKGTQAELLSDKLGVPHISTGNLFRANISQETPLGREAKKYLDAGNLVPSDVTNRMVESRIAEPDAAKGFVLDGYPRTVDQAVALEKMLQQSGSKLDGVVSFEVADDVVVGRMLGRGRDDDTEEVIRNRMQVYRDETAPLLQHYDGLVLSVDGVGEVDEVNARVLRVLGR
>NZ_CP006850.1|WP_025347241.1|1020417_1021740_+|preprotein-translocase-subunit-SecY
MLSAFVSAFRTPDLRRKILFTLGLIALYRVGAALPSPGVDYGAIKRCIDVVNGGDSGGIYQLINLFSGGALLSLSVFAIGIMPYITASIIIQLLTVVIPRFEELRKEGQSGQNKMTQYTRYLSVALAILQATGLVALAGRGLLLKDCKEDILADNSVFGMIIIVLVMTAGAALVMWFGEQITERGIGNGMSLLIFAGIASRIPSEGKQILDTKGGLIFGLVCVAAFVVIVGVIFVEQGQRRIPVQYAKRVVGRKMYGGSSTYLPLKVNQAGVIPVIFASSLLYLPNLVAQLTQSQNSDSWWQKIIQQYLVNPGNPVYVAVYFALIVFFTYFYVAITFNPEERADEMKKFGGFIPGYRPGKPTADYLNYVLSRITLPGSLYLGAVAVLPNLLLHIGGGGGSANSFLPFGGTSVLIIVSVGLDTVKQIESQLMNRNYEGFLK
>NZ_CP006850.1|WP_025347240.1|1019771_1020218_+|50S-ribosomal-protein-L15
MTPIKLHHLRPAPGAKTEKIRVGRGEGSKGKTAGRGTKGTKARKNVPARFEGGQMPIHMRLPKLKGFNNPFRVEYQVVNVGDIARLFPQGGAIGKDELVAAGAVRKNQLVKVLGEGEIGVAVQVSADKFSGSAKEKIAAAGGTATELA
>NZ_CP006850.1|WP_025347239.1|1019589_1019775_+|50S-ribosomal-protein-L30
MAQLKVTQIKSTIGAKKNQRESLRTLGLRGIRQSVVREDNAQNRGLINVVRHLVSVEEETA
>NZ_CP006850.1|WP_025347238.1|1018952_1019588_+|30S-ribosomal-protein-S5
MPGRQRRDGGNGPAGQGGNDRDQRGGGRDRRGGDRRDNAAEKNQLERVVAINRVSKVVKGGRRFSFTALVIVGDGNGLVGVGYGKAKEVPAAIQKGVEEARKGFFRVPMIGSTITHPVQGEAAAGVVMLRPASPGTGVIAGGAARAVLECAGIHDILAKSLGSDNAINVVHATVAALKMLQRPEEVAARRGLPIEDVAPAGMLRARAGQGA
>NZ_CP006850.1|WP_025347237.1|1018495_1018903_+|50S-ribosomal-protein-L18
MAQTETQKAARKPLGKDASTRRRVSKARRHFRLRKKVAGTAETPRLVVFRSSRHLHAQLVDDLAGKTLAAASSVEADVRALEGDKTAKGKKVGELLAARAKAAGVEVVVFDRGGHDYHGRIAALADAAREGGLKF
>NZ_CP006850.1|WP_025347248.1|1027775_1028108_+|hypothetical-protein
MADSIEVDVDALTKAADLPEEVSRKVRGVIDTLNGTLTGIENDSSNQPWGNDKSGKKFADGDKGYKATRKNMIEGGYSMADALHQFADGERTAADQFRASEGGSTEGLGG
>NZ_CP006850.1|WP_025347249.1|1028110_1031107_+|hypothetical-protein
MTMPNADTTEWTQILGSANGGKLQFDTKDIKAATDAAALLIANLEALAQSVRDARADQVGAFSYLQSSRDLAGVYSKHGTALYDSLMTHANVVRDQYDTFVAAGKTFDAHEEGSKFNFDNLANPKKTNSNVTVPTATSTGSVVADLGMDMVDDSWTMPSFPEAIQGYGGKTDQVTINIENAESLDWDQLIQLGQTIHSQPPMDLSGFWDGMSTALTDHLTKYADQIAKLQADWTGDASTAAVNAVRNYKNSAQDLIDAIKVTGASLRYTSDWLEATRKSMPAPGAKEKTGCKNHHTNEFRDNYKKYYAEPMKSTISTIPTIEIPGQASEGSNSGSGSGNGNGNGNGNGNGNGQGNGNGNGNGNGNGQGNGNGNGQGNGNGNGNGQGNGNGNGNGQGNGNGQGNGNGQGNNQEQLQEAYNEGYQAGYQEGSGQGNGNGQGNGQGNGNGQGNGQGYGDGQGYGNGEGSGNGEGYGNGEGYGSGNGDGYGNGDGYGNGEGTGNGEGYGNGDGYGNGEGTGNGEGYGNGEGSGSGYGSGSGSGSYGSGSGSSGKNGQGSQNQNGSGSGSGSGQSNQQQQLPNLNDLLNSYGLGDQSGGGSSGGGSGSGSTPYSGPSRTGSGSSGSGSGSGSSNIPSGYSKNQQSGAGAAKNGQQQPSLDDILSGLAGQQDSEVPTNGDVNPYGDSVTTGSGNPLESLLGQGTGNSSNPLESLLGETTGNSSNPLESLLGQTTGNSSNPLEALLSGGTTGSSNPLESLFSGGEQALDQLGRQAHDGLAGLGQLLHGIPGFDQFLASNPQLSHLLAGIPGLDQLVPGGGLEGLLSSNPELKNLLSSIPGLDELLTGTGDTDPMHSLADRLRELGQTPGMEGLSDIAAQLDPGGGGDSAGSGGGGADFGGDGSGSGDGTTPPRQLDESRPPDKFPRASLPADVSSYGPGQHDSYDQQAGQPGQPGQPGMAGTPASSAGNNGGQGQHRRPKYLTSTDWLDDAMGDTPFRVKPVIEP
>NZ_CP006850.1|WP_025347250.1|1031103_1031895_+|ESX-secretion-associated-protein-EspG
MSRWTLTDLEFKVLCDTRFFGLVPAMFSITSRIPYMDEYEREWRRTRAELESRGDSAFEAIVDTMVLPEVLVGGEVWEDADFDNPRKRVRFYAGRLGSRGFLVTQIPGETLNHAEGFTITSIDPRALGDTVVRLLPPAEPGRRGPIEIDVDGGVGGRAPSSGSMVADDDDDDYGLTSSVFFDIPADHCGTVRLTQGRSKFGPRGRISVARLWRDLPGDGRYVMPLEDPAPVAIGMGSAGLSDWIDTEAELILERMGDYQEVEE
>NZ_CP006850.1|WP_025347252.1|1033605_1034046_-|D-tyrosyl-tRNA(Tyr)-deacylase
MRILVQRVSSARVTVDDETVGQIEPPPGVPHGLLALVGVTHTDTPAIAKTLADKLFRLRILDDERSAADLNAPILVVSQFTLYADTAKGRRPSWSAAAPGPTAEPLVTDFADALRNLGATVATGRFGAHMQVSLVNDGPVTLLLEG
>NZ_CP006850.1|WP_025347253.1|1034199_1034520_+|hypothetical-protein
MANEIEVEVAKLRTAAGKTQDVRDHIEQVLTRLHGKTSGYGNCWGDDTLGEQFAGTGEGDGYLAAAENMVTGARGFADAFQKVSTGQTDSATYLETMEHGNTDGFR
>NZ_CP006850.1|WP_025347254.1|1034516_1035017_+|YbaB/EbfC-family-nucleoid-associated-protein
MTNEHMQAELVGILGEAKEQLRVIAEIQRDRAELVGTASVRKNRVTVSVNADGAVIETKFGAGIEDLSYAEIARAVTEAAQQASKDLAEKHRVLMAPLQERRAKLPKLTDLIEGMPDVRLPTAPEPSLAPPDSPDRDAEYGEDELRFEDAETVPAEPERRVTDSSW
>NZ_CP006850.1|WP_025347255.1|1035033_1055124_+|hypothetical-protein
MIEFPSWLEWLGAAIGMEWPHGNEDDMWALAGDWHTAAGELREILHLMDEAKSATLAAYPAGDGQQQMSDTFDSMRSGKDSLEALAGYFDQIGDSVDGGGTQIQYTKLMFYSTLVITAADIAAVWIFPPTAPAEEAGIIVATRVAVRVMFRRMLSTMAGWAGRLAENALVRFLFRHVLLNAALGALQEFAVQEIQIWQGHRKSLDLNQLGVTTFAAGVGGAAGGGVGEALGRKFGNAFRNEAGDITSKWGVNLTRAGIGASSGLVNSAAAFGGSIAWQFGSDLAHGNLDTALDNLKNTHVDWRMFSAGAITGGGSALNHNFAHNHFENSPFWKLNAPRVDLGNIGDLHNFQHDGTVPNVHVDAPNGNGVGANGNGLHGDPQTVHGDPGSSGPVRGGPVSNGHDSHAGGPTVTAGTHEAPVAGAGSAPEHTAPQDYSDTSAPGPQTPAHDRAGPVDSNVPSDSESGGPVASDSSSPVGHQGATGHDSTPPATSDTPVSHTSTHESPTTAATSGPEGTHSQADTPAASTSGASAAEPSAASGPAASSGPAASSGPAASSGPAAASGPAATSGPAASSGPVSSSGPGAATGASPIDTRGASPVGGSDAPRTGEVRTPDARTGTDGRAASDLNRGATGDGRTPARAGSADTPGARPAADSRVQARVTDSESPRAGSRTGTTEGDRSTAKPGRADTGAAQERAGAGPRPDKGPGGEPSRDARDRPENARTPGELEEPVAPHESGEDSLPPERDSTAGRDREESVSRNETAPRDEAGPRDTTRPLDEAGPHDETASHDSDKSSPTGRIADRPTRADDPPAQDADPGRRDDQGTPDAVERTPHDPEASTPHDPDAAGPGEAEHTGVRNGEHAAPGDSDGAAPRDGEHGGSKDGERTPPRDAEGAGFRDAEGAGPRDGEHVPPRDSDAARPRDAEHAGPGEGEHIGDPVARDADGNTSGRSRGDEFAPLPAESEGHTPLADRTGDSNETPSRRDSVEDDPVAGARDDAEARPHPADEPAHPESDGAQDKSGQEAPRRRPAAHGDNDGTLNKPRDSESSDTPQRKRDDGLVVRPEDQAAPGMPAHPADVEHAQARPRREDQASDQHAAPESPKPPARDESTRGRCAELALRLIREMTGSKTIRLPERAVGPEGMTAAEVQADAGGRMVRVSDHDAIARRLAGMRKGAMALVVDGYHAGPGRRVVGAHAYVMIHEGGGRIVVRDESTGVVTDHPADLPADLHDTHMILFDRKGRPVHPLTPEQREALARQQDPEAVRIRQALDDHSGRVRELLLRTPTGRRILAGLTDSRYTDHVDRSASADGRYGSFRRGDITAVVYADGRGQIAQALTLAHESVHAERYLNGESPADRPLELSRDDYVREMVHEEAMASGRRFQMAAELRELGYQIVERPPEAAYRRAYETALRGLEGPGAHEIAHEVAVDHLRNYLEHVSQNESGRTYADHYRDVWNRAHDVARTPSDDSIRYVPDDPAVRERIRSTALERHIAAVRLNEHAAQLERIADRVSDRIPYDPTMRRDMVQHLISEQLRAVGHELEQGGLPPERAAELRRLGHDLRRMSDLVDRHHNTLAEVDRLRSAGAADVARQLLGDMIADAPGAEVLGDHFAVIPGEPERILVAAGPGDHQRVVRAAPPEIVERLARGAEPEYLNVRTGDNGEIRYERATRPDPAREESAEQVEPRDLAARASEAVIAELQRQLNRVPVGSWAVDTLRARGVTVEHESGGGSRYEPGRKRLVLDIGGTDAEQMAALVHGAIHAERAHENASEDGVLARDRMEREEYVDHMIDEESAAHAMEFNALAQLREAGHRIPDSPLERIYRDAFADARERAAAREDLPDDPAARDAELDRIANDAGIDAIRPAVADHAPDGGASYARGYREAWDSANPPQDDTTAVQRDRPPAQVPDPDGSTYVNTYGGDPVYGIKGWVDEHGVLHYEIRVGPDTPPGREMFQDLMNGLGDRVEGIQDEWYDGGALTDNLDSFNAGVQHGFTPEESARRTFTGKLAEELGYTEVTFGDPDLRGDTGLDGPLGENTGVTVVFRHPDAAGTDSARAHDPDESGARHDPGNEEVFTGGAIRPRDVYFQDAWAKEAYERFRADDSDVDDIAGHLADTPRADGRVGFTRDEIARLKQHLMRDEHLLRDYETGGHSRRRFDESADIAEAWIRLRAGRPLAEDVVLLEHELREAQYLAEHPDATYAEAHDHANQRFNWEDNVPERTGERYDTLWRNDNGDAGVLRPDQGGPGRGGVPVRDDGGTPRSPADHRQADQAVPRSGRSDPRHDGGGRGEDLRQVPDRGDLAGEGHDPGVADRRPEQSGGRNAAEPPRRGEVIVDLGGEQVRLRMVADGNGHWRVESAEPVEPGQRAPGAEVEPAKPGRLRSLWQRFTGGYEGHNPKYPSGSGQDGKYQTEITEDFGHLFDIHALETLSDHDISVNYMRLMKESVTLWINREHAPLLKHLTARVELQAGDHIPMHTRDGREYAYWNEDADPAEVAAMHKYLRDMGLGHLVDESMPRDLPRSHGESEAPPDNPADELRAAADRLGVDLIDLSPETLRRALDTAEYQNLRRAAVIEALRDAAHRYNAEHADIPYRPQSISDHNPLGRFLKEVIIAQGDDPGLLNWRGVNNGAESGRDFDVMNVENPDERIEYDPDDESGRDDGLRAFFENSLRRDQIRDERATWADLLAAELSRLEPDQLDAALNELRDGVHERAGEIRDFADQVDEFRKHFPANDVRELPPRRPGEPGRLIVLDVHGDHEQALAGALDRHPGLAARLNNGEVRAEKWTVVVDENNQAHVRHLGDIDAHPISVEVQGRHLDGLLVRDGDGNWHVAQPPAEPAPMAPHARTPDEIRAVRDDLARELGLDPEQITPELIERELRANDLRALQIEALLDHARSSDAIESFHDLANARDRLAQITGVDDAQQVTPEHVGEQITGKVRRPLREQRVEMLVKYYDKLSGYLKGRGEDRGPLVEARDALVRALGAEPEEVLPSKYSKELEYKPDPMGIDEGKLAALIHDRAGEPGVRDAVTDFVRVLGDTDPFTDGLRLDLATDPRVFDGEVPMHDPEALRHLREVIGDGRRLFDAPEPDGEAVAGARPNRDWARLLGHDLIDATPEQYVRAYEAYRDGKIEKHERLNAAQREEVHQRLREEVRQRATDLRALSELNDRYHQAVADLPENRRARIDQLSREWASAWTERERARQFIVDHAHELRVSPEELLADDLKDGSALDDLFDDLGSRTIRGENRADFARRFQEFAARHEALFDAARRFHDNDVRVADLDAELRGAVERDVALSHDEGDDGDGTAAAPPQGPPKKPPQAPGGAAEEPKSEGDSGASGTPPRSETPAEWGLRMRAENASWSARMAARHALRMRELADEAVARDPDGPDGSMAWDARMAADRAEWEARFAAQRADWLWDLVGNDRHPAEPKQEPDAGAPEQAAASDAGKAAPEPGGGDPMLDGGSGTDKANQEAGGEQGAEKSQETGGAPDPIAEAQARQEAAHNELRRIARDLGLPDRGEARELEAAITRRLDAESAEQQAIIDRTDLRPDEWSAARERAQQRMNELYGMRRAAMRAARDFQEARIAEGRLRAANPQVSQVAEERSPGKVESQEPGSESGDGDEGTGGSPAKSGDSDSDGGSGAKTEPDAEPTAAAPGGGKRPPSDGGSDGGKLPPGDSDGSKSGGGKRPPSDESGTDSDGGDDGSGASPAKPGDSDSGGGSGAKAEPEAEPAADAAGGGKQPPRDGSDSSGRRPPGDGGVDGPDVKSDDSGTGSGDSAAKRGAQVAADNSGSRSDGGDSGAAVAGGGKRPPGDGGGSDDNGEQPPAGDGSEDGAAHSDSNTLQLRESEAPAGQGSGEPARPTWHQDGPQQEHRPVTRALRKALRELADAGAERVRAWTRMNARAHDLGLRPDEIRREILREAIARTADDPGIAPAARDELHALLDDLDNGRTRLELDRRAARLGVPLPSDHQVADAIRDRLAPPAQRRAELSIELGERRTVDLRRLERLAREFGVDPEGRTRPELQRAVREAVNNHRETIPERQRRATVRLVDRYRVSAANESARRAEAQHAAERELMQLRAGFDDRGPRISGVSYRRFRFDAPTRMRMEGAVGERGRWVGVGAGADPELRMPARERTRQAAEGFDAVYHRIELDHHGRLWVSEHHPDVTEAPPTRPGPPRRPGDWMPGGADHEHQPGDRALRRRISDLGAELKRRNDLSDKNFAKIVRLAEDLGIDDAWRMRPRELAVALRELIAERRARADALWNRAEIPRADLQKFFEDRRAEEARAEETESLGKILLGLLRVHDQTLVAAGDRVAADAALLAARDVLAGHEGRPVDADGRPVDPESAVGRLVPGHDGAPDRLVVVAPGANPDRIIDPATRRALLGDDGEFVFHQVRVDTDGRVIVTEMHEPPTELGHAPRPELESPRPAEPEQPAPDIEPVADPQAALDAKVRERAQIAADLEFWRSKADHRAEPFGDLDLSRNRWSETLRQLRGNTMQYVRDSAGLDAADVARHEQLNPQQVREHTDRIDKLAAALDRFFHFEDRLDAIDREIHDLEQQGARHDASLAEDVRDELGRVADEHRAAVQRAKPLRRSRDELSRLLDDPAQRTPENLRRLADAEDAVRRAEHEIDRFNDERVALTGAWNDAVDEHWRAVNGSDETPALHRLNEHVWFDRGRAPAEDGTGGRPARLIVVAGRSAFDHPDVPVRDGDPDAPVRPADDRFDAPLLDALALHPDLAVLLKDPDVVIDRLMVTGELAAGDRDGGGQIRAHVDTMAPVEIRRDELPAHPRGRMGGDRLPFAGDTIVRWRGVDGWHDVREGQARGLHAYQPKLPRGTKLDKHWQAEVEGWRLPPKGWAAFGGTDNSHIPYRQREEKMPDGFSGTMAAEPFQNMVEPLLIRLISDHWPELSYEEILTLSEAGRAELWWHQGPGPKPEPPPGWDEEAHHAMPLDGALYTIGKRWVQLYDMARKHPWILGPLQRRPEIGQWVRDHTGGLPDGPFDPKHPLLRKVPIVRTFRGWKGWKPGPRTDLQPAHRPWSAADHAPPRDRVEFSTPRQDRDIARWAAVQRWADRVIGRFADDAGNADVGRIVDQLTRARDPLLDPADPGGARLDALNLARHPDGTPLTRAELTERIQLVKDHLMRNTMWVRDHADPTGRMVQKPYDRLPHVADAWLRLTGEGDGDGRTSPHDEDLLLLDDAYDEAKYLAEHPGASWHDADLEAARHGYDWDTNRRRLSGHLVVRDGRPLHPDELPPDAPEHDGDKKLRMSRLPYAVDGPALDTSWLPPRARWAADVLAETRARQRFPGLPDDPVDALKQLALQDNALRRALTAPWARDPLLDLAVRAGRVELLVDADPAERPTLAQRLGEPEQAVRPDELPDTLTRLRDDLTRRIGEAADRAPTELPADPAGARPALDGGADEGGESGDVAPVGDGADQGSEHGDARVAPIGDGAAQGGESGDVKVVPVGDGAAQGGESGGVEVGPVGDDAGQGGEPGDAEAGPGGGREPAGPLQQLGPLEQHELTSGRAEVERLAVERARLANEMERLRAERDAATGTERDRAAAAYEQVRAQVFALTDRITDAAGPDFLAAQGAHPVTNQVGIIDGDHPVVIVVGLRSDGTGGPPHDAELVAAAAAHPEAAEALAHPDVEIRYIRLAVDSQGHAFVAPLESPNQPPAAGPTRTPPPPDGGHDDSGNTVDQQGDPADGADPTPAQPDRTAASPKGDQGGPGQSDGVSEPEEAAPREGDGASDGEQSVPKQGDDIPDGDAIQPKQDGAVPEQRSQARRADNESENEQGGLEPGADEPGSEEGQHKPGEEAVQQQQGEARRAVAESEGSQGVRKPGAAVPGSEKGQPKSDDGAAAEQGGARRAGDASESEKGEADAAGDDGAGEQGDSGASGAEESQHGQHSGGRRGKGDGSGSGDRGRAGSARRGQQPPDGGDPDHGDDADAQARRPRKTYITPVPHVPHNAEFDWPDYEPKRIDINLPPPPIPTPPPHQPPPHEPPPHKPGPRPPGGGHNGNGDHDGHGHGHGHDGRGHDHDGHGRDGGDHDHPGHGHGGHGRDHDGHGHDGHGHHDPDGRGHGHDGRGHGHDGHGHDHDGRGRDGGDHGHPGHGHDGHDGHDGHDGHDGRGHDGHGHDGRGHDGRGHDGHGHDGRDHDHRGHEHDHGGLGHDHDHRGHGHDRRGPGRPGHGQDRCDHDGPGHDRQGHDHDHHGRGRGADPSGHHGGGHDHHGPGHGADPGRGGHGHGDRGAHDHGPHGGGHGPLDGVWPGNGPGRTHGLPGVHDPHDRNQDVVPEKPGIPVGDPASKPNIPVPPWLSGGTRGVPPLPLPGSNGGPSGNVPNPFGDAIPHPGEPPWPPRLPAQPQVDHNPNPRSAPENSDTPAVGNGSGSGRGGDVGNEPSGYGYATGSGYGDHDGGRQGGPGQSGTGYSDGIGGDGHRPDLGGNGHRPGSGGNGYGDGIGDRNGDPYRSGHGLGNSRSLGDQQTPVDRPFSLGEPSVRALDPNTQQQNGFPQNGFPPVLPPLPNGGRPAAGTPRAHRPAPPENQVPAPPRILVQEFGGFRCAEVDPLTGSLHETAEPMVPFSGVYSDLDGVEIVFFRADGRLFVRVAGQLIDADDLAVIVHWQRSGRRNAEFTVTRAGLAVCSVRYRRRKPEIDLGLWVRDVLDNPAHRMQIFAEAPGVL
>NZ_CP006850.1|WP_051494940.1|1055707_1057093_+|hypothetical-protein
MRELSHDIARELAASAPEGWRELTAVFAVTVVVGGGEVVFTDDEERMLRAEPPESVLDSVREHRDLSASFEGGPWWRLLVQLDREGHLNVDYDFGDDPFPDDQLLTPEAYLADLQAYPRERIPVWLAAYIGHDDRQSRPPAEAARQIRADRAAGVVPVVSDNDFPDLATLWSRWSVMAAAFVAAGSQWGPRVLPSLGWFEGSRRGGCTLYLLPGGRAVLSGGVWDAPALDAAYNRGEPMPRLYAGAPEWVSNSVLNPRFGNGLLSFCYWWEDGRWYRGESPAADELSDALPGVWTSATVAQVICGLIDGETGDDLRAAVDTLVAAAEANVVTRETLVSVFGDDGSFDIDGAFNQISMAGATFTGPAPLPETAALDRVRRHITEQETDTDRYPLERLCADRISVGWMVYVPTDPDEVAIGRAIFYVADDGVLEQSSSSIAPSIYADGFEQRFRERRGALRAG
>NZ_CP006850.1|WP_025347257.1|1057258_1059172_+|hypothetical-protein
MAPEPTVATGNPFPALSDYTKNHTSGKDALKFEPEAALGVAAAAESTIAALKTLQLYTDDLTAGKPVSNLPSGTAMGTKFGSEATDFKQVLEDHKTILGQMIDTFIQAGKAYGKVDGFNSELLDNVSSKPDYMWEADGLDPIGDPPKVPGTKDDLNHPVDAMDNKAGIQSFQSTTISPEAPDYMSWFDLYQVGNYIRTSKVAETLADHAGTWWWMATEINKVYSDLLNKIDSVTVDKWKGPGREAAVAAVQAYGKSIPTLSNSIKGTGDLLLYSSGWINETQYSMPPNNDADAQTQQDYIQATRDLFRKTYVYGMNQSATHVPVIPAAASAFGQLPANPFNPTGQNPPGDQNPPGNQNPPGNQNPPGSTPPGSTPPGGSTPPGSTSPSAEQQAAQKQAEQQQKQALAQQQKQAEEYEKQQKEYQKQQQHQQQEQQKQQEQYQKEQQHQQAAAQQQQEQQQAMSAVQQLMSAAQQGVQQLMQAFQQVAQTMGQQQAQDALNKAGLGDIPGLSDALDPLSALGGGGGGAGGGGGGLPGGVGAGVPGMSALSRDLAQASKLFPRASTLSSAITGNAVESATGRAGAAPMAGTPGSPGAAGAGAQNQQGKEHKRPAYLDSVEHLEDALGDAPVVVKPVVEK
>NZ_CP006850.1|WP_025347258.1|1059168_1059981_+|ESX-secretion-associated-protein-EspG
MTRSWNFTDLEFVVMWRHLAGEGPPRPFVYTTDIPLEDDFQRECTRLRDRMLARPDHTLFDAVREVTQPDIAVLAWGFDGHDPHRGEGAVRILAARREDRGYLLTQLPGRTLLHAGGFTMVQCDPLRLADMIADALPEVESGDSGHIVLPPDQESKAGVLEAHYVSVASASSAPQLWDSYDEPEVASGQRFLDIVPERSGTIEIAQGISRFGPRGRTIRHLSWRDHPGDGRYVIQAGPPRAAVGVDRKGLIAAINAEIITVVRAIKDERA

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Crispr_ID: NZ_CP006850_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_3

1103928-1104035

Orphan

Consensus_repeat	Method
CCGCGGCGATCGAGCCGGTGATGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_3

>merge|NZ_CP006850|3|1103928-1104035|CRISPRCasFinder
CCGCGGCGATCGAGCCGGTGATGTAGCCCGACATGGCATCCGGTGCGGCCAGCAGTCCGGTACAACCGGCGAGCATGGTCAGCACCGCGGCGATCGAGCCGGTGATTC

>NZ_CP006850|3|3|1103928-1104035|CRISPRCasFinder
CCGCGGCGATCGAGCCGGTGATGT	AGCCCGACATGGCATCCGGTGCGGCCAGCAGTCCGGTACAACCGGCGAGCATGGTCAGCA
CCGCGGCGATCGAGCCGGTGATTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025347301.1\|1109473_1109779_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP006850.1\|WP_025347292.1\|1095781_1097293_+\|type-VII-secretion-protein-EccB	unknown	unknown	gnl\|CDD\|368288
NZ_CP006850.1\|WP_025347296.1\|1101217_1101400_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_081769117.1\|1109105_1109417_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|377587
NZ_CP006850.1\|WP_158436145.1\|1098882_1099170_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347290.1\|1093423_1093984_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|377026
NZ_CP006850.1\|WP_025347299.1\|1104617_1108670_+\|type-VII-secretion-protein-EccC	unknown	unknown	gnl\|CDD\|274858
NZ_CP006850.1\|WP_025347304.1\|1112311_1113526_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347291.1\|1093985_1095668_-\|type-VII-secretion-protein-EccE	unknown	unknown	gnl\|CDD\|274857
NZ_CP006850.1\|WP_025347295.1\|1099166_1101221_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090
NZ_CP006850.1\|WP_025347307.1\|1116540_1117752_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_038551951.1\|1101557_1102973_-\|type-VII-secretion-associated-serine-protease-mycosin	unknown	unknown	gnl\|CDD\|274856
NZ_CP006850.1\|WP_025347303.1\|1111114_1112305_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347305.1\|1113603_1115220_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP006850.1\|WP_025347306.1\|1115296_1116544_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347293.1\|1097289_1098576_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|273324
NZ_CP006850.1\|WP_025347289.1\|1092312_1093296_-\|DUF5593-domain-containing-protein	unknown	unknown	gnl\|CDD\|375482
NZ_CP006850.1\|WP_025347308.1\|1117894_1119295_-\|type-VII-secretion-associated-protein	unknown	unknown	gnl\|CDD\|274863
NZ_CP006850.1\|WP_148306719.1\|1109870_1111088_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347288.1\|1091500_1092310_+\|S-methyl-5'-thioadenosine-phosphorylase	unknown	unknown	gnl\|CDD\|236107

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025347301.1\|1109473_1109779_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	5.68631e-07
NZ_CP006850.1\|WP_025347292.1\|1095781_1097293_+\|type-VII-secretion-protein-EccB	gnl\|CDD\|368288	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B. EccB is a family of largely Gram-positive bacterial transmembrane componenets of the type VII secretion system characterized in Mycobacterium tuberculosis, systems ESX1-5. Translocation of virulent peptides through the membranes is thought to be mediated via a complex that includes EccB, EccC, EccD, EccE, and MycP. EccB, EccC, EccD, and EccE form a stable complex in the mycobacterial cell envelope.	0
NZ_CP006850.1\|WP_081769117.1\|1109105_1109417_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	3.06587e-05
NZ_CP006850.1\|WP_025347308.1\|1117894_1119295_-\|type-VII-secretion-associated-protein	gnl\|CDD\|274863	TIGR03931, T7SS_Rv3446c, type VII secretion-associated protein, Rv3446c family, C-terminal domain. Members of this protein family occur as part of the ESX-4 cluster of type VII secretion system (T7SS) proteins in Mycobacterium tuberculosis and in similar T7SS clusters in other Actinobacteria genera, including Corynebacterium, Nocardia, Rhodococcus, and Saccharopolyspora. This model describes the better-conserved C-terminal region. [Protein fate, Protein and peptide secretion and trafficking].	2.82174e-27
NZ_CP006850.1\|WP_025347290.1\|1093423_1093984_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	1.71293e-36
NZ_CP006850.1\|WP_025347299.1\|1104617_1108670_+\|type-VII-secretion-protein-EccC	gnl\|CDD\|274858	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa. This model represents the N-terminal domain or EccCa subunit of the type VII secretion protein EccC as found in the Actinobacteria. Type VII secretion is defined more broadly as including secretion systems for ESAT-6-like proteins in the Firmicutes as well as in the Actinobacteria, but this family does not show close homologs in the Firmicutes. [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP006850.1\|WP_025347291.1\|1093985_1095668_-\|type-VII-secretion-protein-EccE	gnl\|CDD\|274857	TIGR03923, T7SS_EccE, type VII secretion protein EccE. This model represents the transmembrane protein EccB of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccE1, EccE2, etc. This model represents a conserved core region, and many members have 200 or more additional C-terminal residues. [Protein fate, Protein and peptide secretion and trafficking].	1.68522e-82
NZ_CP006850.1\|WP_025347295.1\|1099166_1101221_+\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	1.09674e-12
NZ_CP006850.1\|WP_038551951.1\|1101557_1102973_-\|type-VII-secretion-associated-serine-protease-mycosin	gnl\|CDD\|274856	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin. Members of this family are subtilisin-related serine proteases, found strictly in the Actinobacteria and associated with type VII secretion operons. The designation mycosin is used for members from Mycobacterium. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair].	2.51699e-121
NZ_CP006850.1\|WP_025347305.1\|1113603_1115220_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.76752e-105
NZ_CP006850.1\|WP_025347293.1\|1097289_1098576_-\|MFS-transporter	gnl\|CDD\|273324	TIGR00891, Carboxylic_acid_transporter_protein_homolog, putative sialic acid transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	2.31487e-161
NZ_CP006850.1\|WP_025347289.1\|1092312_1093296_-\|DUF5593-domain-containing-protein	gnl\|CDD\|375482	pfam18007, DUF5593, Domain of unknown function (DUF5593). This is a domain of unknown function found in Corynebacteriales.	5.39921e-20
NZ_CP006850.1\|WP_025347288.1\|1091500_1092310_+\|S-methyl-5'-thioadenosine-phosphorylase	gnl\|CDD\|236107	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase.	7.94401e-165

>NZ_CP006850.1|WP_038551951.1|1101557_1102973_-|type-VII-secretion-associated-serine-protease-mycosin
MFGQRVVRVAAVAAVVGLSASVGAGTAGADRPPPIVPGLMPDGPPMGPKDETEQASNTPCASTQTGGDGPTVPDAQRALGIDKAWQFSRGAGQLVAVIDTGVAPNPRLPDLIAGGDYVSHTDGTEDCDAHGTFVAGIIAASQVPGQGFAGVAPDARILSIRQSSSLFQVKGRSLQKAPDEMPDAYGSTTTLAWAVRHAVDMHATVINMSLTACKAVSEPFEDRALGAAVQYAAEHDVVVVAAAGNTDKECKNAKNPVFDPLDPTADPWSKIDYNVSPARYDDYVLSVGSVDSNGQASKFTVPGPWLGVAAPGENLISLDPHFNDAQSKGTATAKVDAQGRAEPITGTSFASPYVAGLAALVRSRFPELSAPEVVKRIEATAHAPAEGWNPYIGYGIIDPLAALTDQVPAQLPPKAQHPVKSVQLSVPATPPTPDHTARNVALIGSAVIAIMCILGLLASFPLRRRFQTRDK
>NZ_CP006850.1|WP_025347296.1|1101217_1101400_+|hypothetical-protein
MNWADTMAKIADEHADNVRRIRYRIEEVDDEARAANAALGVVASDEENGGDTAKEPPRQR
>NZ_CP006850.1|WP_025347295.1|1099166_1101221_+|hypothetical-protein
MRRTESSSTGIDKLLDTGKEGLNFFGTFVPRYKAWTGANPAGGDEAALTTRYDQQRGMDVEPLRTIGTAIGQGLDGTIGDAIRIQQLRLSELPARWSGSPGADNAAQLVQRVNGLVGGEHDNLSGIAQALSAAAEQLENVVRTKADAVRVDFATATLADRTADQIDKVIACARGDFGGVADVEEQRTKVREILPEIGTGDEPATYAKDWLDRVFVPALDGKIAAFTTLTDATHTAVNGVYEQLGGALESLGASPYTGPDGQPSAATSLQSGQPGNSSALFGSNPSVTPAALITTAPAAVDGTDPSASKPTATPISAVTSDTPLSQAAPVAATVPAAAANSGQGQSKQSGKPVSKNQGQGGAQDQGQGGAQDQSQGGAQDQSQGGAQDQGQGGAQNSGQDGGAQGDGDGSGKGGGMPQVTDMGKVGEWRPGDIANVLTAASQITGTVPDLLTHIGDPLKAVGELFKDVVGSEGITGLIHEGVDAATKIDQLVDHHAHPGEAAEQAPDPGNGNDPNGDSKGPQDNSQGHGEQPGHGGQADHGGQPGRGEQPGGAGDQSGPPQNSSPAGHEGKSIAAAPTQQPAAPAQGIPIASAPAAPNASSAMSPSGFLGGHGAPARSEGEQEHRPKIQYTAPDLDDGPAFVDAAEPDHPRAHDTGNRTPPDPAEPQPITADPDEADAEPEVQRA
>NZ_CP006850.1|WP_158436145.1|1098882_1099170_+|hypothetical-protein
MQAISANLQQSATELSDSAVTLSGAVEGFTAADAGHEYGAQGERVVSGLEGLSKRMFMWANCVNDTGAVLGQAATNNGRVDQGSASSISQGGVTV
>NZ_CP006850.1|WP_025347293.1|1097289_1098576_-|MFS-transporter
MAVAGRQRLTPDQRNSFIAAQLGWTMDAFDFFLVVFVYADIAVTFDMPKSDVAFITTATLIMRPVGAMLFGLWADRVGRRIPLMVNVAFYSVAGFLCAFAPNFTVLLILRLLYGIGMGGEWGLGAALAMEKIPAERRGFFSGLLQEGYSFGYLLASLASLLVMNWLGLSWRWLFALSVIPALIILVIRTRVGESEAWESSREHMRLTQTSLRDVLMNPVVIRRFAYLVLLMTAFNWMSHGTQDIYPTFLSAVDNGGAGLSSATAKWIAVVYNIGAIIGGLVFGSLSQKYGRRYTIIFCALLGLPIVPLFAYSTTAAMLCLGSFLMQLMVQGAWGVIPAHLTELSPDSIRGFYPGVTYQLGNLLASLNLPIQERVAESHGYPFALTVTIVPVLIVVAFLTLIGKEAKGIRFGTGASALPEVRSGPEPGR
>NZ_CP006850.1|WP_025347292.1|1095781_1097293_+|type-VII-secretion-protein-EccB
MPSKPTTRWQVSGYRFLVRRMEHALVRRDVRMLHDPMRSQSRAYAVGLVLGIVALAGCGVLALLKPQGSIGDNKILLGKDSGAVYAVIDGVVHPALNLSSARLAVGEPAKAVSIKESELAKKPRGALIGIPGAPSSLNFDGSGKGRAWSICDGLKNDGSQDLSTTVIAGDPSLGSKASRLGEGAALLVQGRDAAYLVYDNQRARVDMNDPKVTEALGIRGKTPRPISPGLLNAIPEVLPIEPPKIVDPGGMPTYSLNNHRIGDVVHVATKDQYYVVLRTGLQSISPLTADIIRNSNTAVSTDPEIDQSQAVQQNVSNELPVQKYPVKAPTIVEAKDQPVACMSWKPVAGASDKTDGSKRATLAVITGYSLPIPDNAQTTPLAQADGSGQNVDAFYSTPGSGFFVQTTGIETDSQRRDSMFFIADTGVRYGIKDANAQKALGMDAEKAKPELAPDQIVGLLAAGPTLGRQEAMVAHDGVAPDPAPAKQLVQSKQDQQAQQQSPN
>NZ_CP006850.1|WP_025347291.1|1093985_1095668_-|type-VII-secretion-protein-EccE
MAESSGTDSRPLFGRISLPNLLAAQVLGLIVGLIVLIAGVPGWYALGAAIVAGLLILIPIGKRTIASWIATLWRYFTRQDYDLGDTVDFRGPDGRSLGLYWEGSRVVAVVEVLPPRGGLTRIDRNTVHASHLLPLPELAQCLSQHDILLSGIDIISHGHRSRSGTPAGPIYESLLGPLPATAHRTVWLAISFDALACPEATSRRGGGTEGAGRAVTIATQRIVRALEDADCSSRVLTAPEIRQAVWQISAGVDPRELTQRWRYAELGNSVNIGAAVDPKQLGSDLLAQLWVAPSRGTTVTVRLRPGTSAETVNIGAAWRLTARELPEKTNTKGMVSLSGRHRQSLLAHLPIAIPGMDDTVPMSQYPIDVVGVLHLPSSGCGQLIGSDAEGNGVAVRLVGQGIAAVYVAGELYLAQQLVFRALAVGERILIRTDRPQAWEQLVSTIGNPERLTIAMETHQSDAGFTAAVVDGVLAPAPHAGVTTIYLTGDPMGWPATKPDLSIHQPGAMGNHVVMRTGTAQVDLTLVSIPRETTYIGDPRGRRPAPQQQQQPRRRPAPARR
>NZ_CP006850.1|WP_025347290.1|1093423_1093984_+|NAD(P)H-dependent-oxidoreductase
MDDPLRLEVIVASVRPERFAPVVADWFLRTARAVDGLDIGVVDLAHTPLPVDLTTDPATEAYARRIGAADGFIVVTSEYNHGYPAALKTALDVCKREWRAKPIGFVSYGGLSGGLRAVEQLRQVVAELHMVSIRETVSFHEAKRKFDAAGETADGAAIDAAQRLLRQWSWWAGHLRTARAADPYPS
>NZ_CP006850.1|WP_025347289.1|1092312_1093296_-|DUF5593-domain-containing-protein
MILGHWLLIETLDVPATWSVLAVDTAPRRWKSLARTVPARLMPILTAAAATGEVVDRQLPKSRYAWSGHHARAVALPGPDDRVHAVQMWVGPGRPPPPPAVATQLLDARTRATEVRPVGLGPAFDRGRTIWVGAESFEHVERFDDALELAATVARGTPGSRWCGELVVRTPHGLRTLMMATRNSTADPHLWRGLLADITDSVAPQAKSFEAATVDTLVHRNPGMYLAVLDTERVRVIRWISPPVPGLDWTGGTDERKLPHPADRERIIAARNDIRAGAPSISLPGLRLAAVGGGWLSVDAEVSPLPHGPDGAGIPHFALARIDLRDH
>NZ_CP006850.1|WP_025347288.1|1091500_1092310_+|S-methyl-5'-thioadenosine-phosphorylase
MDSQPRPALAIIGGTGFYDFFGDDATTLEVETPYGAPSAPITVGEVEGRRVAFLPRHGRKHEYSPHTVPYRANMWALRSVGVRRIFAPCAVGSLRADWGPGTVAVPDQLVDRTSGRDQTYFDNGGIHISFADPYCDELRSAAVGSAVPELPLRDSATMVVVQGPRFSSRAESRWFAGQGWELVNMTGYPEAALARELEMCYAAIALVTDLDAGLEAGQGVSAAAVFAEFERNLVPFKTMVRRAVAAVEQERTCAGCAVHDGVTLPFELP
>NZ_CP006850.1|WP_025347299.1|1104617_1108670_+|type-VII-secretion-protein-EccC
MSTVRFQRRARREVPRSPGGEVTLQPPPEIPRAIPGNLLGKLMPVVMVVGMGGMMAIMFTKGGGIASNPMSMMFPMMMVFSMVGMFAGQGGKGQKAAEANEDRKDYLRYLDQVRKDVDETAAQQREAVEWSHPEPGLVWMLAGTSRMWERRPGDKDFCHARIGLGGQRLATRLVSPETGPVEELEPIAAVSLRRFVRTHSTVPDLPTAIAVKGFATIQLNGDRAQARDMTRAMLLQLCMFQAPDQVLVAVVRGTDTASEWEWTKWLPHTQHPESQDGVGTQRMVYGSIRELTDGLNPLLHNRVRYSRNQPANQNLVHIVIVVDGGLLEAEEDSLRESGYEGVTILDLCGYAPRLAVSRGIQMVVENGECVGRGATGNMERFALIDRISARQAEQVARRIAPFRVAPVQRGGEVVVEESNAEVITSWAQMLGLGDIGTFNPENGWKPRYGRDRLRVPFGLGADGLPVYLDIKEAAESGMGPHGLCIGATGSGKSEFLRTLVLSLLATHSPDQLNLVLVDFKGGATFLGLEGVPHVAAVITNLEEEADLVDRMKDALAGEMNRRQEVLRDKGNFANVSEYEKARAAGADLDPLPALFVVLDEFSELLSQHPDFAELFVMIGRLGRSLHVHLLLASQRLEEGKLKGLESHLSYRIGLKTFSANESRQVLGVPDAYNLPNSPGGGYLKSDSGEIQRFQASYVSGPYVGGGAQREVTQAGIVGGEIDINVREFFAGHVAFRSGDRIPLPSEPSAIEEAKPDESAEKISNVGMLVQRIQGHGRTAHEIWLPPLDAAPTLDQLLSRSILTGEYNPVAGLRTAIGIVDRPYDQRRDPMIVDLSGARGNVAIVGGPQSGKSTALRSLIMGMSLTHTAEQVQFYCLDFGGGTLAGLEGLPHVGSVAGRLDVDKVRRTISEMTTVVRQRELRFRQLGIESMADFRRLRGTDPASSPAAAGAHEDPFGDVFIVVDGYGSIRQDFDTLEQPIMNIATQGLSYGVHVVIALNRWAEARPALKDQIGTRIELRLGDPMDSDLGRKVAALVPQGRPGRGMTTDAKHMLTALPRVDGDSNPESLGAGVADAVARLAAATPGRPAPRVRMLPEVLNRDDLLHNVLGGWPGHVDASTRNVQIPIGLNENELAPVFLNLAEQPHVLIFGDSECGKTNVLRNIIHNIVASNTPENAKLIIGDYRRTLLGVVEGRHVAGYAPSAEMLDNMMKELVGLLRARMPGPDVTQQQLRDRSWWSGPEVYVIVDDYDLVSTQSGNPLAILTEYLAQAKDIGFHLIIARRSGGASRALYEPLIGRMKDIGTIGLLMSGSRDEGALLGNVRLSEMPPGRGTMVARSGNSLIQTAWTPAPA
>NZ_CP006850.1|WP_081769117.1|1109105_1109417_+|WXG100-family-type-VII-secretion-target
MPFHADAQQLAGFVQKMQDKHDAIGRMITNAHNHATTLQGPAFQGGAGTAFQNTFEQFLTSANKMNEALMQNSQNLKSAGAKYAEMEEQSLGDLKNQTLDWRT
>NZ_CP006850.1|WP_025347301.1|1109473_1109779_+|WXG100-family-type-VII-secretion-target
MSDFGEISYDFGTIDDAGSGIKSEAMNITGALEDMEREFQEFITTHWTGSDAADAFNAVQTNWRQQSDELSASLAKLGAHTVGAGENMQGADVLASKLIAG
>NZ_CP006850.1|WP_148306719.1|1109870_1111088_-|hypothetical-protein
MTYRTGIPMRTLRAFACVSASVAVALSLTSCGSSVAGSATPAEIDVRKLDIGNYSPDPSNILDKYIPLIDSGRELAIMRLGDKIANGDEIDPSLIYNTGVAIDEPKDRHTLGDSKPFIEALEQNGMLYGLQMHKRQRPDDAPVVGDKLVNLTVYQFPDDNSAKAAADTFESIDLAFAQDQNQPVHLDKYPDARSHWRPGIRTMGSWIAVGHYMLEVFIRVPAPQLPDLTSFIQHIYDVQVPMLRSLPPLSKKEILHLPYDPEGMLRRTLDPQKIFMPDLLNYAYYTAHSARNFTNPAGRAMMDLGKVDAASQRVGVTMLWRSRDVDSAREMFEEMRRQAKGPVDPPSGITSSYCDQGPADSFDNGSRFRCVIRYDRYVARLISNQLKDAQQLAAAQYAVLANSWQ
>NZ_CP006850.1|WP_025347303.1|1111114_1112305_-|hypothetical-protein
MQISRAIACIFVTTATALCLSSCGSSVTGTPAAAEIDVRKLDVGSYPTDPIDMRFNYIPQAYFGNQLAAMRLLDKIPIGTEIDPSLTYNGANAVAEAKDGLNNDLSPDFVTALQQNGMLYGLMTSKKQKDGSDSTDGDEQVDITVYQFPDSKSAEAAAKAFEDADFAVAPDQNQAVQLDKYPNALSHWRPGIRTIGSRLAEGNYMLDIFARATQPELPRLTSLLEHVYDVQLPMLRGLPPLSKRDILHLPYDPNGMYSRTFVKNDFSGPSLLVSGSFTTRGFLNITNSDGKALADKGKVDAVSSNSDDTILWRSSNEESARALVEELRHRTLKPAAPPTGIPDSFCDEDPKSYSWSDDRYRCVIRYKQYTARVASSQIRDAQQRAAAQYAILASSW
>NZ_CP006850.1|WP_025347304.1|1112311_1113526_-|hypothetical-protein
MKLLATTARFVTTVGMTVALVSSAACGSDSDAVTDPVVDLTKLDLGAYQGKPADLGLPKNMYVARFMEANRLGDVLPLPHEVDPNLTVGEASETHAFLDVGKEFHLGPIFRWLHEENFNSSVRNYVGGFATSASSNEAYTLSYELVSSALLFSDPESARVAAGELSKADFYGDVPVEPTALEKYPDSVARWQPAKQLLTTWTANDKYVIITNVINHENAELGVSDPKFLTDLAAKSIAATTDSLRNFKPTPVDQLMKTPVDPDNVRSLALRRPTGDSFINIPGTFDLHGAMQFAPNPKILEKAYRDNGVDRVAFDAGELVRAKDSAAAQKIFEERSAANRLMRKVESPKGLPNAVCLNYKGPDTKIRYYCHVRYGRYAAVVFSQQLLDAQQRISAQYSILANSK
>NZ_CP006850.1|WP_025347305.1|1113603_1115220_-|serine/threonine-protein-kinase
MVMSPGTIVGGYRIVRQLGAGGMGTVYLAKHPSLPRMDAIKILSGELSSNHEFRGRFEREANLAAGLDHPNIVSVYNRGEEHGQLWIAMQYVDGTDASAELARDRHSMTPLRALRIVTEVGKGLDYAHRRGLLHRDVKPANFLLSKKEDDDDEERVLLTDFGVAKSTDDATELTQTGSFVATIAYAPPEQLQGMSVDSRADIYSLGCSFYKLITGQNPYPATQPAMVMMGHLYEPPPQATAINPGLPPAIDHVFARALAKNPADRFTSCREFTDAAANALTPGHSPVRTSTSPTYPIQVFDPRNQTDPRNQAIHQTQSGIQTQIGQRSDTDLSRLLESKPKSRRPIVLGGLGAVVAIALAVGIGIWATQGSSKTHTPSTTTAAAASTPAAATSYTSVQQAREANPAFAGKTITVLDVTGDKTFAVYLGGTEQTKFLENLGFVYNLQYPRNGDEPTPRPITDAYEDLHTPADSYILAVRSDPNAGGGGLLGLPYAISSSRATVIPLDDPVAVSAMRNWSGTSESTLLQKLAPVLHNQVK
>NZ_CP006850.1|WP_025347306.1|1115296_1116544_-|hypothetical-protein
MTTRITRMAVAVLSLCALASATGCGSTVGGWAGPSEIDVRTLDIGSYQTEPLDIHVDYRPGFTYAPQAAGMRLAENVVTADQVDPKLTMRGDSYTFTSGVMPESVGDDQPMSDAAKRNSMVYGFTTTGRDKNADWGFSGWPKPDQPNATILSLTVMQFNDPDAATRAATDFYNTDFNAYKDRNQPVTIAKYPDAHAHWQPGTPSIRSFLAHGPYVVSVLALTPSPDIDGLTGLTVRALDTEFPLLDKLKPITDEETVTLPWDPDYLLSRALNTGGSGRPQYGDDNGVFGPHAILHYMADRKLATQSVSAVKANEFAKTSDALVVRTADAASAKKAVTDRITFQGGGPAVDPVPQVPDSSCVENTSKSSKMGDPKRYICIVAYRNYIGYVTSSQLVDVHQRAAAQYALFANSQWQP
>NZ_CP006850.1|WP_025347307.1|1116540_1117752_-|hypothetical-protein
MRGSVRLLAAAVATVALTATGCGSDDPSPAPAAEPTIDIATLDTGPYDANPRDMGKPKNPGQAALMEAERLGNAMPLIVDIDPAFKYTGVFDTLAFIDAKTSVMKDFTDLSNFTEDAPDLISGFGVYGRNDSDNLGIELVNTAMIFPTEQHATEVAAALERRDFGRDPLSQAVALPRYPQAHAHWVQGKQAIDVWVPLGRLVIFGAVFDQAKTWFHKTDLTDLVTRVTTSLDKVVPALSAFHPTPPDKLMDQPMDIDGMLGRTMVRPKEAQGEWLNAPGAYTGYAGVAFASDPAETRRWFEENGVDRFADYGNQLYRARDTAAAIKVRDELGDPAKHMKRAAAPKNLPVAKCREYQGREKMAIRYYCSVYHGRYAAFAAGEQLLDAQQRISAQYAILVKADGK
>NZ_CP006850.1|WP_025347308.1|1117894_1119295_-|type-VII-secretion-associated-protein
MSTVDLILTDTRLWARSEATHWDGAPSVTPTSDGASLVVGEPLQPPYPAVSVVRLADADRIAFAPVLPTIADAFAAVFGAVLTNLRLPTPCERLTVVAPSEWGTRRRNALTAGARRLVGEVTVEPLALRVAGLSASTSQLQRIAVVEASPLETTVTLAGRSGTETWLEGCEHEPAFGSADLAEGRGVDVLADVIDRLLGGHKPSYLVVVGIADPAILGALREELTRRYGFGVDLRAMSGLDLIRGGPAGPAAPHAARPQPQAPWTGPLHEHAAAAQPAPRRRTPIILAAAALVAVVIGVAAAVVLTRSGNDPADTATGTTARTTAAAPSAETFGRVRAQLPAGWHIASRSDTRVDLSPDDGARQRISMVQKNLPAGSGIDEVAATLEAQIGKRPPGTVTPLRRDVIFGGRPGLSYEEHPADGSTVRWQVMVDSGLQVSVGCQYPADNWSPLAGACEKFVGDLRTGP

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Crispr_ID: NZ_CP006850_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_4

1274759-1274862

Orphan

Consensus_repeat	Method
TGGGACGACGACGAGCTCGCCAAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_4

>merge|NZ_CP006850|4|1274759-1274862|CRISPRCasFinder
TGGGACGACGACGAGCTCGCCAAGAAACTGGCCGCCCCGCGCGCGACGTCGGAGCCCAAGGCGGGTTCCGGTTCGCTCTGGGACGATGACGAGCTCGCCAAGAA

>NZ_CP006850|4|4|1274759-1274862|CRISPRCasFinder
TGGGACGACGACGAGCTCGCCAAGAA	ACTGGCCGCCCCGCGCGCGACGTCGGAGCCCAAGGCGGGTTCCGGTTCGCTC
TGGGACGATGACGAGCTCGCCAAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_051494620.1\|1273067_1274207_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090
NZ_CP006850.1\|WP_025347463.1\|1280071_1280263_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347466.1\|1281818_1286669_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|137505
NZ_CP006850.1\|WP_025347464.1\|1280462_1280930_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|180484
NZ_CP006850.1\|WP_025347457.1\|1271359_1272763_+\|NAD(P)H-quinone-dehydrogenase	unknown	unknown	gnl\|CDD\|236112
NZ_CP006850.1\|WP_025347456.1\|1270658_1271141_-\|gamma-glutamylcyclotransferase	unknown	unknown	gnl\|CDD\|372719
NZ_CP006850.1\|WP_025347460.1\|1275508_1276684_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP006850.1\|WP_025347450.1\|1263866_1265426_-\|phospho-sugar-mutase	unknown	unknown	gnl\|CDD\|100092
NZ_CP006850.1\|WP_025347462.1\|1278313_1280062_+\|glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223651
NZ_CP006850.1\|WP_025347469.1\|1289023_1289476_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|214628
NZ_CP006850.1\|WP_038552032.1\|1269489_1270620_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|349936
NZ_CP006850.1\|WP_025347451.1\|1265432_1266212_-\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|236183
NZ_CP006850.1\|WP_025347465.1\|1281015_1281780_-\|DNA-glycosylase	unknown	unknown	gnl\|CDD\|223344
NZ_CP006850.1\|WP_025347468.1\|1287387_1288917_-\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143448
NZ_CP006850.1\|WP_025347461.1\|1276685_1278179_-\|glycerol-kinase-GlpK	unknown	unknown	gnl\|CDD\|198362
NZ_CP006850.1\|WP_051494619.1\|1268068_1269265_+\|M20-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349921
NZ_CP006850.1\|WP_148307118.1\|1266301_1267216_+\|ribonuclease-Z	unknown	unknown	gnl\|CDD\|234602
NZ_CP006850.1\|WP_025347453.1\|1267324_1268023_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|119339
NZ_CP006850.1\|WP_025347449.1\|1263235_1263865_+\|uracil-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234653
NZ_CP006850.1\|WP_081769130.1\|1286897_1287359_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319924

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_051494620.1\|1273067_1274207_+\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	5.94331e-05
NZ_CP006850.1\|WP_025347465.1\|1281015_1281780_-\|DNA-glycosylase	gnl\|CDD\|223344	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair].	5.02173e-51
NZ_CP006850.1\|WP_025347466.1\|1281818_1286669_-\|ATP-dependent-helicase	gnl\|CDD\|137505	PRK09751, PRK09751, putative ATP-dependent helicase Lhr; Provisional.	0
NZ_CP006850.1\|WP_025347464.1\|1280462_1280930_+\|flavodoxin-family-protein	gnl\|CDD\|180484	PRK06242, PRK06242, flavodoxin; Provisional.	5.38797e-74
NZ_CP006850.1\|WP_025347457.1\|1271359_1272763_+\|NAD(P)H-quinone-dehydrogenase	gnl\|CDD\|236112	PRK07845, PRK07845, flavoprotein disulfide reductase; Reviewed.	0
NZ_CP006850.1\|WP_025347456.1\|1270658_1271141_-\|gamma-glutamylcyclotransferase	gnl\|CDD\|372719	pfam13772, AIG2_2, AIG2-like family. This family is found in bacteria and metazoa.	2.6255e-30
NZ_CP006850.1\|WP_025347460.1\|1275508_1276684_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.37993e-111
NZ_CP006850.1\|WP_025347450.1\|1263866_1265426_-\|phospho-sugar-mutase	gnl\|CDD\|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NZ_CP006850.1\|WP_025347462.1\|1278313_1280062_+\|glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|223651	COG0578, GlpA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	1.41045e-178
NZ_CP006850.1\|WP_025347469.1\|1289023_1289476_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	1.34224e-38
NZ_CP006850.1\|WP_038552032.1\|1269489_1270620_+\|amidohydrolase	gnl\|CDD\|349936	cd08014, M20_Acy1-like, M20 Peptidase aminoacylase 1 subfamily. Peptidase M20 family, uncharacterized subfamily of uncharacterized bacterial proteins predicted as putative amidohydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	0
NZ_CP006850.1\|WP_025347451.1\|1265432_1266212_-\|purine-nucleoside-phosphorylase	gnl\|CDD\|236183	PRK08202, PRK08202, purine nucleoside phosphorylase; Provisional.	1.0534e-123
NZ_CP006850.1\|WP_025347468.1\|1287387_1288917_-\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143448	cd07130, ALDH_F7_AASADH, NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B. Alpha-aminoadipic semialdehyde dehydrogenase (AASADH, EC=1.2.1.31), also known as ALDH7A1, Antiquitin-1, ALDH7B, or delta-1-piperideine-6-carboxylate dehydrogenase (P6CDH), is a NAD+-dependent ALDH. Human ALDH7A1 is involved in the pipecolic acid pathway of lysine catabolism, catalyzing the oxidation of alpha-aminoadipic semialdehyde to alpha-aminoadipate. Arabidopsis thaliana ALDH7B4 appears to be an osmotic-stress-inducible ALDH gene encoding a turgor-responsive or stress-inducible ALDH. The Streptomyces clavuligerus P6CDH appears to be involved in cephamycin biosynthesis, catalyzing the second stage of the two-step conversion of lysine to alpha-aminoadipic acid. The ALDH7A1 enzyme and others in this group have been observed as tetramers, yet the bacterial P6CDH enzyme has been reported as a monomer.	0
NZ_CP006850.1\|WP_025347461.1\|1276685_1278179_-\|glycerol-kinase-GlpK	gnl\|CDD\|198362	cd07789, FGGY_CsGK_like, Cellulomonas sp. glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases. This subgroup corresponds to a small group of bacterial glycerol kinases (GK) with similarity to Cellulomonas sp. glycerol kinase (CsGK). CsGK might exist as a dimer. Its monomer is composed of two large domains separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The regulation of the catalytic activity of this group has not yet been examined. Members in this subgroup belong to the FGGY family of carbohydrate kinases.	0
NZ_CP006850.1\|WP_051494619.1\|1268068_1269265_+\|M20-family-metallopeptidase	gnl\|CDD\|349921	cd05672, M20_ACY1L2-like, M20 Peptidase aminoacylase 1-like protein 2-like, amidohydrolase subfamily. Peptidase M20 family, aminoacylase 1-like protein 2 (ACY1L2; amidohydrolase)-like subfamily. This group contains many uncharacterized proteins predicted as amidohydrolases, including gene products of abgA and abgB that catalyze the cleavage of p-aminobenzoyl-glutamate, a folate catabolite in Escherichia coli, to p-aminobenzoate and glutamate. p-Aminobenzoyl-glutamate utilization is catalyzed by the abg region gene product, AbgT. This subfamily includes Staphylococcus aureus antibiotic resistance factor HmrA that has been shown to participate in methicillin resistance mechanisms in vivo in the presence of beta-lactams. Aminoacylase 1 (ACY1) proteins are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	1.56704e-154
NZ_CP006850.1\|WP_148307118.1\|1266301_1267216_+\|ribonuclease-Z	gnl\|CDD\|234602	PRK00055, PRK00055, ribonuclease Z; Reviewed.	5.43026e-113
NZ_CP006850.1\|WP_025347453.1\|1267324_1268023_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	1.81766e-39
NZ_CP006850.1\|WP_025347449.1\|1263235_1263865_+\|uracil-phosphoribosyltransferase	gnl\|CDD\|234653	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed.	7.25661e-103
NZ_CP006850.1\|WP_081769130.1\|1286897_1287359_+\|VOC-family-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.11625e-22

>NZ_CP006850.1|WP_051494620.1|1273067_1274207_+|hypothetical-protein
MKHRKPGRPQQRGLAATSLPLATAAVVATILASGTAAAAPTEQPTVPTTPAQPGATDEAPAQDGNTDSPNGQNTPNGQNTPNGQNTPGAEQNGPQQNGNTQPGVTTPGQPGTTAPRPGGTTPQPGVTTPNQNGPKPGQGSTQPGVTAPRVAPLPVPGQGNQVAPAGTPDQHNPNDQADQLKPGQQPDQSVVTPNGPLPQQNNNQMDTLRGQQGSDHSAEQAQWTSPSLQAAPAAPVVQMNGPHTEVGANVDGGALLPGYVANTHHFSNLDGYVGTVGYNTPNGVGDAGVSVEFVEANKIKVTSYTHATGFDDLKSENYVDTTQPNAAKAAVEGWIKQQPGGAAALDAAGQIGRLPQGDIAPQTVNVAGATTQWGGTVQY
>NZ_CP006850.1|WP_025347457.1|1271359_1272763_+|NAD(P)H-quinone-dehydrogenase
MARIAIIGGGPAGYEAALVAAQHGATVTVIDSDGIGGACVLWDCVPSKTFIASTGVRTDLRRARDLGITVHMAQAQVRLSEVNSRVKALAQAQSSDIRSKLQAAGVTILNGSGRLIDQIPGLATHLVRATLADGTERVMEAEVVLIATGASPRVLPGAEPDGERILTWRQLYDIPELPETLVVVGSGVTGAEFVSAYTEMGVKVKLVSSRDRMMPGEDADAALVLEDALAERGVELVKQARADAVERTADGIVVKLSDGRTVTGTHALMTVGSTPNTHDLGLERIGIELDRGGYLRVDRVSRTAVPGIYAAGDCTGLLPLASVAAMQGRIAMYHALGEGVVPIRLKTVASAVFTRPEIATVGVSQTAIDNGEVPARTVMLPLNTNPRAKMSGLRRGFVKIFCRPATGVVIGGVVVAPIASELILPIAIAVQNNLTVNDLAQTFSVYPSLSGSVTEAARQLMRHDDLD
>NZ_CP006850.1|WP_025347456.1|1270658_1271141_-|gamma-glutamylcyclotransferase
MPIYAAYGSNMDPEQMLKRCPHSPVYGTGWLEGWRLTFAGDDIGWEGPLAQVVEDPGSRVFVVLYDVSAEDEDSLDRWEGSDFGIHKKLRLRVTPNSGSGSQPVLAWLYVLDAYEGGLPSARYIGVIADAAEKAGAPSEYVHALRTRNSRNVGPGTFGSM
>NZ_CP006850.1|WP_038552032.1|1269489_1270620_+|amidohydrolase
MREHGDDLIGWRRHIHANPELSRAEHATTEFVESWLVKADLEPRILPTGNGLICDIGPSGPRLALRADMDALPLQEYTGRPFASTVPGVSHACGHDAHTAILLGTALALAELDELPVGVRLVFQHAEEVMPGGAIDMVAAGAMDDVSRVFALHCDPRLEVGRIGVRVGAITSAADTVELVLDSPGGHTSRPHLTSDLVYAIGTVITGLPGLLSRRIDPRTSTVMVWGAVSAGKAPNAIPQTGMLTGTVRTGDHATWSLLEPMVREIVDGLLAPTGVRYQLNYKRGVPPVVNDEFCTRMFEDAILGLGPDALSDTPQSGGGEDFSWYLEEVPGAMARLGVWSGEGPQLDIHQPTFDIDERALAAGVRVLTNLVLQAR
>NZ_CP006850.1|WP_051494619.1|1268068_1269265_+|M20-family-metallopeptidase
MPRSADDRIAAADDAVSAAEPELIALSHSIHAEPELAFAEFRSVHKTLIPLRERGFHIETPVADLDTAFVATYGSGELVVGICAEYDALPEIGHACGHNIIAASAVGAALALAAVADRCAITVKVFGTPAEESGGGKVLMLERGVFDGVAMAMMVHPGPFDIVAARSLALADLSVTFHGREAHASAAPEYGRNAGDAATVAQVALGLLRQHLRPGQQLHGIVESGGVAPNIVPGFAELLYYLRADDSASLDDLRQRASACFEAGALATGCTHEIRALAPTYTELTPDPALLCVYREQIIGMGRTPLAPELEAARPLGSTDMGNVTNAIPGIHPVIGIEANGAVTHQREFAAAAVTSSADLAVIDGARALARTAIRIAGDQFHRDRLLGRSIRRQEDIR
>NZ_CP006850.1|WP_025347453.1|1267324_1268023_+|enoyl-CoA-hydratase/isomerase-family-protein
MPYLDRDGDVFVLYLGNEGQTDSENRFHPDWIDEFHARLDEVEAVEGQAALVTVATGKYFSNGLDTDWLFGNMDRMHWYLDRVHSMFTRLLTFGMPTVAALNGHAFGAGAMLATSQDFRVMRADRGYWCLPEVHLGMPFTVAMNALVTERLTNQVALEAMTTGRRYGAADAIAAGIVDQQADADRVLADAVARAAALAGNRKPNLPVIKRALHHRALVGLNTATTPENLAFG
>NZ_CP006850.1|WP_148307118.1|1266301_1267216_+|ribonuclease-Z
MLVRELVVLGTASQVPTRRRNHNGYLLRWDGEGLLFDPGEGTQRQMLYAGVSAGDITRICLTHFHGDHCLGLPGVLARLNLDQVTHPVDICFPGSGAQNLAHLRGVVPEFAGLREHPVADSGPVALPEAPFTFEAVRLSHRVETFGYRLTEPDGHRFLPERLAELGVSGPAVGRLQREGSVRLDDGRTVTVDQVSAERPGQRFAFVMDTRMCSGVEELADGADMLVIESTFLEAESRLAHDFGHLTAAQAAQAAAAAGVRTLVLTHFSQRYGDLAGHHEEARRYFDGDLVVAEDLMRVPVPARR
>NZ_CP006850.1|WP_025347451.1|1265432_1266212_-|purine-nucleoside-phosphorylase
MLAEQAAEAIATRTEVPQHRVAVILGSGWQSAAAEIATPRASIPMGEIPGFEPPTAQGHQGIVHSVTVGETPVLLMMGRQHLYEGYEPQRVVHAVHTAAAAGAETVVLTNAAGGIRDGMRVGDPVLIADHLNLTGRTPLTGADFVDLVDAWDPGLRALATEVDPSLTEGVYAGLHGPQYETPAEIRMLRGMGADLVGMSTVLEAIAARSLGLRLLGISLVTNLAAGVTGAPLSHQEVLAEGQAAAPRLGKLLRGVLERM
>NZ_CP006850.1|WP_025347450.1|1263866_1265426_-|phospho-sugar-mutase
MLRFGTAGLRGPMVDGPDGMNPGTVARASAGVAEWLRGRCLGGGLVLVGRDARHGSAEFAAITAEVFAAAGFSVLALPRPLPTPVLAFAVRELGAVAGVQITASHNPAADNGYKLYLDGGSQLIPPADQEIERCIDAVAEPIPRLAPVAPAPALLSLPADAGPAELGEELLHRYLTRAAAIPDLVGGPADERIIARRRRIRIALTPMHGVGGETAVAALAAAGFPDVRVVGEQFDPDPDFPTVPFPNPEEPDAADLLLKLAAEIDADLAVALDPDADRCALGVRGPQGWRMLRGDETGVLLADYVLRQAKPDALVATTVVSSRLLGALAPARGARYAETLTGFKWLARAGEGLVYAYEEAIGHCVDPAAVRDKDGITAAVAAADLTARLAAAGSGLLETLDGYALEFGLHAGDQVSLRLADTAAAAEVVARLRDTPPDRIAGVPVACTDLSTARGRMRTDALIFTGDGQRLVIRPSGTEPKLKCYLEVVQPVPARERLDEAKEIAAQRLSELRDFCEGL
>NZ_CP006850.1|WP_025347449.1|1263235_1263865_+|uracil-phosphoribosyltransferase
MRTHTVDHPLVATLLTTMRDARTSNAGFRAALADLTGFLVYEALREVPIRTFDIDTPVATTRGARLAEPPLLVPVLRAGLGMVDAASALIPESRVGFVGMARDEHTHRPVPYMESLPADLSGLPVFVLDPMLATGGSMCHTLRLLVDRGATDITAVCVVAAPEGIAALENSGFPVRLVTAAVDDRLNDDAFIVPGLGDAGDRQFGPRLD
>NZ_CP006850.1|WP_025347460.1|1275508_1276684_+|PLP-dependent-aminotransferase-family-protein
MSPHTPPLSRRLDGLQSSAIRDLLKLTARPDIISLAGGLPDEQLMPRDAIARAAEAALTDPARLQYTESAGWGPLREVLAARESARLGRPVPLSEIFVTHGSQQALSLLGEVLLDPGALVVVEDPAYVGALQVFRAAGARIEAIALDAEGMRVDALAELLARGERPALVHTVSNFHNPRGVTMSAARRAELAALAERYGFWIVEDDPYGELWFDRPAPEAVASYSPNVIRLSSASKILAPTLRVGWMVAPDVVCRGVELLKQGADLCGSALTQQIAADLLADEGWLGAHLDKVRGIYGERATALVGAVRERLGERVVSTDAAGGMFVWVDFTDGTDTVELLPRAVEHGVAYVPGSAFAVSRSLRGSMRLCFTTSDADTLTEAVDRLVAATA
>NZ_CP006850.1|WP_025347461.1|1276685_1278179_-|glycerol-kinase-GlpK
MRRFVAAIDQGTTSSRCIVFDRSGRIAGLAQREHEQLFPRPGWVEHDPETIWRNTEYVIGAALEAAGASADDIAAVGVTNQRETTVVWERATGEPIANAIVWQDTRTANLCERLGGEVGAGRYADRTGLPLSTYFSGPKLRWLLDEVEGVRARAEAGELCFGTMDSWILWKLTGRHITDVTNASRTMLMNLHTLQWDSDICAEFDIPVSLLPQIRSSSEVYAEITSGPLAGVPVAGILGDQQAATFGQACLIPGEAKNTYGTGNFMLLNIGATPVSSTHGLLTTVCYRLGEQPAVYALEGSIAVTGSLVQWLRDNLGIIESAEEIEPLARTVEDNGGAYIVPAFSGLFAPRWRPDARGVVAGLTRFVTKAHLARAVLEATAFQTREVLDAMRADAEDLGVELTTLKVDGGMVANELLMQFQADILDVPVVRPVITETTALGAAYAAGLAVGFWSGTDEIRANWSEDKVWRPAMPEGERVRRYGEWNKAVERTYGWAE
>NZ_CP006850.1|WP_025347462.1|1278313_1280062_+|glycerol-3-phosphate-dehydrogenase
MNEKSHGQHTGELGPEQRAATWESLGANHFDVIVIGGGVVGAGIALDAATRGLEVALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREALRERELSLTTLAPHLVKPLRFLYPLTHRGWERPYVASGIMLYDSLGGAKSVPGQHHVTRSGALRLAPGVRRDALIGGVTYYDTVVDDARHTMTVARTAAHYGAVIRTSTQVVDFLREADRVVGVKVRDSEDGRTTEVRGHVVINATGVWTDELQALSHVRGRFHVRASKGVHIVVPRDRITSDAALILRTQTSVLFVIPWGSNHWIIGTTDTDWNLDLAHPAATKADIDYLLDRINEVLVTPLTHDDIQGVYAGLRPLLAGESDETSKLSREHAVARIAPGLVAIAGGKYTTYRVMAYDAVDAAARDIPQRVSPTITDKVPLLGADGYFALLNQTPQLAQTYGVHPYRIEHLLNRYGALVTDVLDLAEGKSELLQPITDAPSYLRVEAVYAAVAEGALHLDDILARRTRISIEYSHRGTECAEEVAGLVAPVLGWDAEQIRREVSTYTARVEAEVRSQTQPDDVSADALRAAAPEPRPEILEPVPLPQN
>NZ_CP006850.1|WP_025347463.1|1280071_1280263_-|hypothetical-protein
MTYASTMVRRGTRLVTQLVIAALAIAATVLFTCALQHSASGTARTGHDSAPAVTAPPPAAVRQ
>NZ_CP006850.1|WP_025347464.1|1280462_1280930_+|flavodoxin-family-protein
MKTLIVCTSVSHGNTKRVADAMAEVLGARVVEPGEITPAELAAYDLVGFGSGVFNMNLHPRLREFARSLPSGQQRTAFVFATSGFPEPPFRRYLRAFVRLLESKGFDVADTFRSPGYDTWFPLKLVGGIQKGHPDDTDIEAARTFAEGLRTRIAG
>NZ_CP006850.1|WP_025347465.1|1281015_1281780_-|DNA-glycosylase
MPEGDTVYLAAARLRTALAGKTLTRSDFRVPRYATLDLRDRVVDSVGSYGKHLFVRTETLSIHTHLKMEGNWRIYRPGARWTEPGFTARLVLATVDAEAVGFALGLVEVLPRADEHTATDHLGPDLLGPEWDAAEAVRRLAAHPDQPIGLALLDQTNLAGIGNIYRSEICYLRRIHPATPVADVDLPALVDEAHRVLTKAAHEPPWRPLAYGRQRRPCRRCGAAMVVHLLGDPATPNRERGIYFCPRCQPPPPG
>NZ_CP006850.1|WP_025347466.1|1281818_1286669_-|ATP-dependent-helicase
MQQFARATQEWFDGAFPAPTAAQLGAWQAIAAGEHTLVIAPTGSGKTLSAFLWAIDRLATREPPEGPRRTSVLYISPLKALAVDVERNLRAPLVGITRTAARLGAAAPEITVGVRSGDTTAADRRTMARKPPDILITTPESLYLMLTSAARDTLSEVGTVIVDEVHAIAGSKRGAHLALSLARLDQLTERPAQRIGLSATVRPPEAVGRFLVGSAPITIVAPPAPKTFDLSVRVPVADMTEPGESDQPGSIWPHVDAAIVDLVLAHQSSIVFANSRRLAERLTARLNEEYAERLGEIDSAASDSDTDPVHPVRKDHAPPAQIGSTTEVNHGAAPLLARAHHGSVSKEQRAIIEDDLKSGRLRCVVATSSLELGIDMGAVDLVVQVEAPPSVAGGLQRVGRAGHQVGEISRGVIFPKHRTDVVHCAVASMRMTAGQIEELRIPAHPLDILAQQTVAACALEPIDVDEWFDTVRGTGSFASLPRSAYDSVLDLLSGRYPSDEFAELRPRVVWDRDAGTLTGRPGAQRLAVTSGGAIPDRGLFPVFMVGEKASRVGELDEEMVYESRVGDVFALGATSWRIEDITHDRVLVSPAFGLPGRLPFWHGDSLGRPAELGAALGEFVRTAGQAIERAPAERIDALVRDADPGTGDISPVAGNGRDESRPPARKSSRRAAATSDGNGDGSARTRSVPDGRRTRKSGGAKAGAELVELEHIVHAAGLDDFATANLVSLLAEQRQATGHLPTDRTLLVERFRDELGDWRLILHSPYGLPVHAPWALAVGARLRERFGVDAAPTASDDGIVVRLPDTTDDPPGAELFVFEPDEIDEAVTEQVGGSALFASRFRECAARALLLPRRDPGRRAPLWQQRQRAAQLLDVARKFPDFPILLETVRECLRDVYDLPALRDLLTDVARRKLRLVEVETAAPSPFANALLFDYIGQFMYEGDSPLAERRAAALSLDSSLLAELLGRVELRELLDTAVIEQLERELQRLTPERHARDAEGLADLLRLLGPLTPEEAAARCADNPGSWFAELVRAKRALEVSFAGSHWWAAVEDAARLRDALGVPLPIGTPAAFIEPVADPLGDLTGRYARTHAPFTLDALARRFGIGPAVAATALHRLAAEKRVVEGEFTPGSAGAEWCDTEVLRRLRRRSLAAARKEVEPVSTAAFGRFLPAWQHIGATPLRGVDGVAAVVEQLAGVPIPASAWESLILPSRVRDYTPAMLDELTATGEVIWSGHSALTAKDGWIALHPADQAPVTLAPAQEIDFTDVQTRLLSALGAELTAGTGDAIALDADGSADTEASAFGGNRIVAVAGGAYFFRQLSDATGLLDDTAVAAALWELVWAGYLSGDTFAPVRARLSGTTRSTTTHRTPRRTPRGRMYLPRPAVPTRSGPPAVAGRWSLLPPRAADNTIRAHATADLLLERYGVLTRGSVQSEDVAGGFALMYRVLTEFEDRGRCRRGYFVDTLGGAQFSTTDVVDRLRSFDTERGGGTGALALAACDPANPYGAALPWPKTSEGAGHRPGRKAGALVVLADGELALYLERGGKTLLTFTEDPEVRTRAAGALAALVHDRRIDSLVVERIDGESVHGNTFATFLSTAGFSATPRGLRLRSRP
>NZ_CP006850.1|WP_081769130.1|1286897_1287359_+|VOC-family-protein
MSDSREPVTEIPADPVQARDPGDPPVPPGALLLELVPVPVTDVDRSIEFYRDRAGFHLDVDVTPAPDVRIVQLTPPGSACSILLATGLPAAQTPAGALRGLHLVVADIEASRATLLARGVEVGEIEDVGGGVLYAYFADPDGNTWCLQHMPWR
>NZ_CP006850.1|WP_025347468.1|1287387_1288917_-|aldehyde-dehydrogenase-family-protein
MTSAPVLPSTGELRDRLAQRLAELGAGTVESGDLPVRSPITGGVLGHLRTSTELDVMYAIDKAHNAFRSWRTVPAPQRAAVVRRLGQLLTDNIDALAELVTLEAGKIGAEARGEVQEMIDVCEFAVGLSRQLYGHTMPSERPGHRLMETWHPLGVVGVISAFNFPVAVWSWNTAIALVCGDTVVWKPSQTTPSTALACHTLLRRAAADVGADPEIHQLVQGDGEVGGLLVDDERIALLSATGSVRMGRTVAPRVAARFGRCLLELGGNNGAVVTPSADIELTTRAVVFAAAGTAGQRCTTLRRVIAHADIVGPLLDRMSAAYQQLPVGNPLDDRVLVGPLVDERAHTAMRSAIQRAIDDGGELICGGERVETGDPDAYYVRPAIVRMPAQTAVVREETFAPILYVLTYHDLDTAIELHNAVPQGLSSAIFTGDQREAERFLAADGSDCGIANVNIGTSGAEIGGAFGGEKQTGGGRESGSDSWKAYMRRATNTVNYSAELPLAQGIRFG
>NZ_CP006850.1|WP_025347469.1|1289023_1289476_+|Lrp/AsnC-family-transcriptional-regulator
MADAPAKPVLDDIDRLLIRELMADGRATLSNLAEKASLSVSAVQSRVRRLEARGVIRGYTAKVDPEALGQMLSAYVAITPLDPSQPDEAPALLQHVPGIEECHSVAGEESYMLLVRVASPRHLEQLLAEIRATANVRTRSTIILQTFYDQ

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Crispr_ID: NZ_CP006850_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_5

1601180-1601267

Orphan

Consensus_repeat	Method
TCATGTCAGTACTCCACTTCCTGCGAGCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_5

>merge|NZ_CP006850|5|1601180-1601267|CRISPRCasFinder
TCATGTCAGTACTCCACTTCCTGCGAGCGTAATCGGGCGCAGTGTGGTGGCCTCGTCATCATGTCAGTACTCCACTTCCTGCGAGCGT

>NZ_CP006850|5|5|1601180-1601267|CRISPRCasFinder
TCATGTCAGTACTCCACTTCCTGCGAGCGT	AATCGGGCGCAGTGTGGTGGCCTCGTCA
TCATGTCAGTACTCCACTTCCTGCGAGCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_158436157.1\|1599067_1599226_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347772.1\|1607886_1608072_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347767.1\|1598321_1599071_-\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	unknown	unknown	gnl\|CDD\|225091
NZ_CP006850.1\|WP_038550323.1\|1608482_1609853_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347762.1\|1594907_1596356_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224169
NZ_CP006850.1\|WP_025347765.1\|1597339_1597561_-\|DUF2283-domain-containing-protein	unknown	unknown	gnl\|CDD\|378367
NZ_CP006850.1\|WP_148306746.1\|1597191_1597332_+\|ribbon-helix-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|289422
NZ_CP006850.1\|WP_038550325.1\|1609849_1610425_+\|class-IV-adenylate-cyclase	unknown	unknown	gnl\|CDD\|143628
NZ_CP006850.1\|WP_025347776.1\|1611284_1612187_-\|RNA-polymerase-sigma-factor-SigJ	unknown	unknown	gnl\|CDD\|236600
NZ_CP006850.1\|WP_025347764.1\|1596874_1597069_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347763.1\|1596374_1596821_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319924
NZ_CP006850.1\|WP_025347777.1\|1612292_1612868_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|377026
NZ_CP006850.1\|WP_051494627.1\|1599318_1601133_-\|nitrate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|224063
NZ_CP006850.1\|WP_081769648.1\|1593665_1594745_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|365803
NZ_CP006850.1\|WP_025347778.1\|1612878_1613316_+\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|226769
NZ_CP006850.1\|WP_025347771.1\|1605915_1606833_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347770.1\|1605426_1605906_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025347766.1\|1597587_1598325_-\|respiratory-nitrate-reductase-subunit-gamma	unknown	unknown	gnl\|CDD\|376889
NZ_CP006850.1\|WP_025347775.1\|1610641_1611355_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP006850.1\|WP_025347779.1\|1613340_1615638_-\|arylsulfatase	unknown	unknown	gnl\|CDD\|293749

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025347762.1\|1594907_1596356_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224169	COG1249, Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion].	4.18105e-108
NZ_CP006850.1\|WP_025347765.1\|1597339_1597561_-\|DUF2283-domain-containing-protein	gnl\|CDD\|378367	pfam10049, DUF2283, Protein of unknown function (DUF2283). Members of this family of hypothetical bacterial proteins have no known function.	2.00046e-07
NZ_CP006850.1\|WP_148306746.1\|1597191_1597332_+\|ribbon-helix-helix-domain-containing-protein	gnl\|CDD\|289422	pfam12651, RHH_3, Ribbon-helix-helix domain. This short bacterial protein contains a ribbon-helix-helix domain that is likely to be DNA-binding.	0.00274698
NZ_CP006850.1\|WP_025347763.1\|1596374_1596821_-\|VOC-family-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.43546e-23
NZ_CP006850.1\|WP_025347776.1\|1611284_1612187_-\|RNA-polymerase-sigma-factor-SigJ	gnl\|CDD\|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	5.28809e-94
NZ_CP006850.1\|WP_025347767.1\|1598321_1599071_-\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	gnl\|CDD\|225091	COG2180, NarJ, Nitrate reductase delta subunit [Energy production and conversion].	8.47285e-42
NZ_CP006850.1\|WP_038550325.1\|1609849_1610425_+\|class-IV-adenylate-cyclase	gnl\|CDD\|143628	cd07890, CYTH-like_AC_IV-like, Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily. This subgroup contains class IV ACs and similar proteins. AC catalyzes the conversion of ATP to 3',5'-cyclic AMP (cAMP) and PPi. cAMP is a key signaling molecule which conveys a variety of signals in different cell types. In prokaryotes, cAMP is a catabolite derepression signal which triggers the expression of metabolic pathways including the lactose operon. Six non-homologous classes of ACs have been identified (I-VI). Class IV ACs are found in this group. In bacteria, the gene encoding Class IV AC has been designated cyaB and the protein as AC2. AC-IV occurs in addition to AC-I in bacterial pathogens such as Yersinia pestis (plague disease). The role of AC-IV is unknown but it has been speculated that it may be a factor in pathogenesis, perhaps providing cAMP for a secondary internal signaling function, or for secretion and uptake into host cells, where it may disrupt normal cellular processes. This subgroup belongs to the CYTH/triphosphate tunnel metalloenzyme (TTM)-like superfamily, whose enzymes have a unique active site located within an eight-stranded beta barrel.	2.77459e-29
NZ_CP006850.1\|WP_051494627.1\|1599318_1601133_-\|nitrate-reductase-subunit-beta	gnl\|CDD\|224063	COG1140, NarY, Nitrate reductase beta subunit [Energy production and conversion].	0
NZ_CP006850.1\|WP_081769648.1\|1593665_1594745_-\|AAA-family-ATPase	gnl\|CDD\|365803	pfam00004, AAA, ATPase family associated with various cellular activities (AAA). AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.	2.19577e-08
NZ_CP006850.1\|WP_025347778.1\|1612878_1613316_+\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	5.75569e-18
NZ_CP006850.1\|WP_025347777.1\|1612292_1612868_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	1.29305e-40
NZ_CP006850.1\|WP_025347766.1\|1597587_1598325_-\|respiratory-nitrate-reductase-subunit-gamma	gnl\|CDD\|376889	pfam02665, Nitrate_red_gam, Nitrate reductase gamma subunit. This family is the gamma subunit of the nitrate reductase enzyme, the gamma subunit is a b-type cytochrome that receives electrons from the quinone pool. It then transfers these via the iron-sulfur clusters of the beta subunit to the molybdenum cofactor found in the alpha subunit. The nitrate reductase enzyme, EC:1.7.99.4 catalyzes the conversion of nitrite to nitrate via the reduction of an acceptor. The nitrate reductase enzyme is composed of three subunits. Nitrate is the most widely used alternative electron acceptor after oxygen.	1.7734e-113
NZ_CP006850.1\|WP_025347775.1\|1610641_1611355_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.3463e-07
NZ_CP006850.1\|WP_025347779.1\|1613340_1615638_-\|arylsulfatase	gnl\|CDD\|293749	cd16025, PAS_like, Bacterial Arylsulfatase of Pseudomonas aeruginosa and related proteins. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.	0

>NZ_CP006850.1|WP_051494627.1|1599318_1601133_-|nitrate-reductase-subunit-beta
MRVMAQLAMVMNLDKCIGCHTCSVTCKQAWTNRGGTEYVWFNNVETRPGQGYPRGYQDQEKWKGGWKLDRRGRLTLKSGSRMKRLLNIFANPDLPTVSDYYDPWSYDYDNLLSAPAMDTTPVARPKSLITGEDTKVTWGANWDDDLGSGPEQVGRDPLLSRLSEQVKLEFEQTFMFYLPRICEHCLNPSCGASCPSGAIYKRAEDGIVLVDQDKCRGWRQCITGCPYKKIYFNHKTGKAEKCTFCYPRVEVGIPTVCSETCVGRLRYIGVLLYDADAVLEAASVTDETQLYPSQLGVFLNPHDPRVIAEAERASISPEWIAAAQDSPVYQLIVDYKIALPLHPEYRTMPMVWYVPPLSPMVDVLSETGHDGEDAGNLFGAIDTLRIPVEYLAELFTAGDVEPVRAALQRLAGMRAFMRSINLGQEPDLSIPGAVGLEPEEIEAMYRLLAIAKYEHRYVIPSGATSRAHELDSLATGCSLDGDGGPGMTAFDVTSEKFALVDANMAAPEEKSTRINLLNWNGGSTEGLVPARNGTAGGGAAHGDRSAPDGHVSANSHAPGADSGASNGHRGANGHGADGNGRARTNGSGEVEYEHVTPETTGTPR
>NZ_CP006850.1|WP_158436157.1|1599067_1599226_-|hypothetical-protein
MRSRPSGEQGAASGEVGGRRRTVPDPRSLECGCDADHRSIAVDAAHARRGRR
>NZ_CP006850.1|WP_025347767.1|1598321_1599071_-|nitrate-reductase-molybdenum-cofactor-assembly-chaperone
MNLLKLRKRPTPVVEMSERGRLLVWRISALILDYPRPESLALLDTMSDAISELPNPVRENLSRLLAHLTATDAHTLARDYVETFDLRRRASLHLTYYAYGDTRKRGMALLRFKHAYRHAGAELSDHELPDHLPVLLEFAATVDPVGGERLLGEHVPVLEMLRLSLTDSGSPYADALAAVLATLPPPTTADRRRIAELAAQGPPDEDVGLEPYSLNSETMHPAMNPDLYSPPSNDSCGTAAPFATSGDRR
>NZ_CP006850.1|WP_025347766.1|1597587_1598325_-|respiratory-nitrate-reductase-subunit-gamma
MSSTVWATLPYIAFTSFVLGHLWRYRNDQFGWTTRSSQVYESRLLRLGSPLFHFGMLGVIGGHVLGVLIPQSWTDAVGISEHLYHVVAVSAGSVAGLAVIAGIAILAYRRLSIPAVRRATTTNDKFMYVLLAAALITGLLNTVGSNLLWGTYNYRETVSPWFRSLFTAHPHPELMVGTPWTFQAHGLIVLTLIGIWPYTRLVHMFSAPVGYLVRPYVVYRSKPAGTTNKRKYARAWQSPVVPPTR
>NZ_CP006850.1|WP_025347765.1|1597339_1597561_-|DUF2283-domain-containing-protein
MHVTYDPYADAAYLALKHPLGEGEAVRQQVVPLRGADMVLDFDDKDVLLGIEIIGAGAVLPDALLRAALSPGR
>NZ_CP006850.1|WP_148306746.1|1597191_1597332_+|ribbon-helix-helix-domain-containing-protein
MRVEKSVYLDEEQALRLKQAAEATGRSAADLILEGVDLVLLRAARG
>NZ_CP006850.1|WP_025347764.1|1596874_1597069_-|hypothetical-protein
MADISRTGKWWPLPRAAAVVVTAVAGGGLALACGLGAIQARPTADAARPAVVRIHGSDTGDRAG
>NZ_CP006850.1|WP_025347763.1|1596374_1596821_-|VOC-family-protein
MDMKLEVVVLPVTDVDRAKTFYTERLGFRLDADFPVDDGYRVVQVTPPGSECSIILGTGVSGAAPGSLHGLHLIVTDIEKAVAELTAQGIAVEGPFRDATGIFHHAGTASRVTGADPERRSYGSFAAFTDPDGNGWFLQEVTQRAPGR
>NZ_CP006850.1|WP_025347762.1|1594907_1596356_-|NAD(P)/FAD-dependent-oxidoreductase
MSDSNIQTYDVVVIGAGPVGENVADRTRAAGLRTVIVESELVGGECSYWACEPSKALLRPAHLYREAAHFPGVGTAISSPLDAAAVLKHRDRMAAEWNDRGQLDWLESVGVDLVRGHGRLEGPKQVAVHTPEGNTVRLLARHAVAVCTGTTAALPPLPGLDALRPWTSREATSAQEVPGRLAILGAGVVATEMAAAWQALGAQVTLIARDARLLGRVEDFAADLVAERLREAGVDLRFETTITTAERTDGVVHLTLADGTHLTADELLLATGRAPRTGDLGLGTVGLAPGVWLTTDDTFTVAGIEGEWLYAVGDVNRRALLTHQGKYQARVAGAVIAARALGSELDTGRYGRHVATADHEAVPQVVFTDPEIAAVGLTTADAARTGRTVDVVDYDIGLVAGAIQHDPGYRGRARILIDPQRQIVLGATFAGRGVAELLHSATIAITGEVPLDRLWHAVPAFPTIGEVWLRLLETYRDQREAS
>NZ_CP006850.1|WP_081769648.1|1593665_1594745_-|AAA-family-ATPase
MNVDDADSPRDVIDALALTPYLDGSQPHAVAAELEHVKPDAPLRPADARVLRTVDDDGTRTSLAAGPGWTLRVVRRGNGSANLDVTAVTEELAREVIATCSADATAEPEADAAQVSMGFWHNGAHGPNRRVRTISAASWPEITGNYGTEVGAAIQRLMAVRAEDVRGRLVLLHGPPGTGKTSALRALAREWSDWCQVDCVLDPESLFANPGYLMEVAIGVDTYDESKRRWRLLVLEDCDELIRGSAKETTGQGLSRLLNLTDGMLGQGRDVLVAITTNENLSRLHPAVVRPGRCLAQLEVGRLSPTEATAWLAREMPDAPPHPISAEGMSLAELIELRDNRSRIQAEPASPMAGDGGYL
>NZ_CP006850.1|WP_025347770.1|1605426_1605906_-|hypothetical-protein
MVRIGVTGHMDISDDTRRLVYDEITRLLAVHDDVTGISCIARGADSVFAQAVLDSGGRLEVVVPSRNYREKKVKPDHAPVFDDLSQRAVVVNVMPFTDTGPEAYEAANEAVVGTCDRLVAVWDGQPGERSGTGSVVEFARARGVPVDVVWPDGAQRAGR
>NZ_CP006850.1|WP_025347771.1|1605915_1606833_-|hypothetical-protein
MFREWDDQFGGGLRRRAVVGQLSEVNELLQDSHPPQIQRRLRRVLALLAEAAATMSWDSGLQTAAQEYYMLAVGSAKAAGDPALCANAMAGMARQLLSLNHYGTVSGRRDLEHQRAVDALEVIRLAQDQFGDAVTPTVRAMLYTREAWAYGKLDRPSAFRRTCDKAHRAFAAADPDCDPYWIRYFDAAELSGTLGGRLLEIARNDSGFAAEAAREIERAIELRVPGRLRSSALDRLGIVEARLLEGELDEAARLGHEALNTVEQTTSDRVRKKLLNVYSRTDHLAGVRSVAELRDRVRPLIIDTV
>NZ_CP006850.1|WP_025347772.1|1607886_1608072_+|hypothetical-protein
MIRSTAHQREQWDIIHRFCDDCLAPIASLEEARRALTVHAGHGLGCLQYLAALSRVSEVMA
>NZ_CP006850.1|WP_038550323.1|1608482_1609853_+|hypothetical-protein
MTTVNSFAHQQKSDAVYLDIAANDHGDEKGALVHRALTRLQTANPHVVEIGPGGGAAVQYLASKLTSGDRVRMTLIEAPGVMSHSLTQAMDAFTAVGTCNLMHGWAKDLSTLIAEPVDVISASALMHEVYSYGGAYAGLHTMMRVLPTVIRHYGFFVYRDVYAVDAPTLHERVVHCYSSQSWLQFLRMFVPHYLVEGAHPYHHHDDEVVARQNSRIVPVAELDTHVCAVIEAPVGLFREVQRHYITLRDHVWRSGILGFEPILDGELSVDWVDFRSGHKRVHYTLTDSVMASRHPTALLAVSERYGDHYVIDGDIFDAVTDAALMAFLAGAELADSRCEPTWHGWLAREGRETYAYLTADDLLTAFAMNSLEGRPDQDAVLMPVCAEDVCMRDRRYYNRFLAKRLANPLVDAKQLILFQNIPAHDAHTVQRALATLQQLCSKRNVARLHTAIHWRG
>NZ_CP006850.1|WP_038550325.1|1609849_1610425_+|class-IV-adenylate-cyclase
MNRMHLIEVERKRAVADAASLCDRLVGLGYREDGQVTEVDVYYSRPDVDYMQTVECLRIRQRGDFCEITYKPPSNPGTHGASHIIAKREINVSLAGIEDADAARVLLEAVGMRELAVVEKNRRVFRHPDRHDTVVALDSVIGAGEFVESEVCATDPQEAATRLEQIERELGIDALRVVTVPYRDLVMMAAR
>NZ_CP006850.1|WP_025347775.1|1610641_1611355_+|CPBP-family-intramembrane-metalloprotease
MRIRRLRRVYLGAEYAALFFGGTTVYNAFLRGRPPIPALLALGLGAGAYLRRAPGFDRAALWRSGALRNEAAPMAALAGSSALALTATVAALRRDALFELPRRNPALWLAVTVLYPVLSVYPQELIFRSFLFHRYAPVFGDGAALVAASAAAFGYVHIIFGSWVSVALSGAGGLLFATRYLRTDSLLTASVEHAVYGILIFTVGLGRYFYHGAAPTRADSRRSRGAVSPDSGSPRYR
>NZ_CP006850.1|WP_025347776.1|1611284_1612187_-|RNA-polymerase-sigma-factor-SigJ
MTDPHLPEVIGERRQLINLAYRLLGSLAEAEDVVQETYARWYALSERQRQEVAVPGAWLTTVASRICLDLLGSARARRERYVGEWIPEPVPGRPEWFGGPAPADPADRVTLDESISMAFLVVLDSMTPAERVAFVLHDVFRYPFAEIADVVGRTPAACRQLATSARRRIDTSKRPSGAERAEVVRNFKRAWETSDIEALIGLLDPNATATADGGGLAVTFRDPIVGRERIADAWMRIAARTTTATLLERTVNGQPGLIAEQDGTVVSVYAFDIADGRITDIWVIRNPEKLRPWIDGNRPA
>NZ_CP006850.1|WP_025347777.1|1612292_1612868_+|NAD(P)H-dependent-oxidoreductase
MTTIGIILGSTRADRRGAQIARWVLDSASRRDDAEFELIDLRDHPLPHFDEAVPPMFGPSADERTRSWAARIAPFDGFVVVTPEYNGGMPGVLKNAIDHLFAEWTNKAVGFVSYGVNGGARAVVQLRTVCGTLGLADVGYQVAISVLTDFENNTTFVPGDRQVAALDTTLDQVLAWSTALAPLRAATHVRS
>NZ_CP006850.1|WP_025347778.1|1612878_1613316_+|nuclear-transport-factor-2-family-protein
MTTTSDEAEIRRQIDRIGAGLRARDLDAVRRQYTDGVVSFDVEQPLQHVGIAAKLVNWAKVLEVFADVSYEIRDLTLTVGGDVAFGHAFARLSGTTSDGTTMGGMWVRVTYGLVKSGGTWLIAHDQVSVPLDVASGRGVVDLEPE
>NZ_CP006850.1|WP_025347779.1|1613340_1615638_-|arylsulfatase
MAVPDHARGYETFTGEIGRTTADSTPAWARPPVAAAGSPNIIVVLVDDMGFSDIGPFGSEIDTPTLNRLAQRGVRLTNYHTTPLCSPSRAALLTGLNSHRAGFGFVANADPGYPGLRLELADDVLTLPEILRAGGYATYAVGKWHLVRDATMNPAAHRDSWPTQRGFDRYYGSLEGFNSFFHPNQIVSDSSVVDVEQYPEDYYVTDDLTDKAISYLKDLRAHDAEKPFFLYFAHVAMHGPLQAKDVDLAKYRGRYAQGWDEVRRSRFASQLAQGLFAPGTEQQPRNTEPGYEAREWDSLSADEQRRFARYMEVYAAMVDSIDQSLGRILDTVEQFGELDDTIVVFTSDNGGTAEGGPVGTRSYLAEFAHVDDPEWVGDVPHDEDLIGTARLGVHYPRGWGQASNTPFRFYKGQTFAGGVRVPFIVSWPKGLPAGELRDEYVYVTDLAPTLLELSGVSRPSVRNGLPAKDFDGVSAAEVLRDLDARSRHVEQYSEMTGHRGFYRDGWKLLALHEPGRDVDDPHWQLFDVRTDPTELRDVAAEYPEKVAELARAWDDAAWRNTVFPLLTRQDLARRRPEEARLSAPVRIRPGTPTLERYRSQKLIAYRDFTVTAELDGYRAGDEGVLVAHGDPQGGYLLYIENERIVFGFNSFGRYTETSAPIGDGVREITLTAAVRPRLRWDFTLTLDGAPAAELTDRVQLVGMAPWTGISVGVDARGPVAWDLRERRGPFRYTGALRAVTYTPGQPRVPEAVVRAVESEAELIAE

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Crispr_ID: NZ_CP006850_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_6

1907370-1907443

TypeI-E

Consensus_repeat	Method
GCATCAGGGTGTCCTGTCTTCGC	CRISPRCasFinder

1 spacers

cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP006850_6

>merge|NZ_CP006850|6|1907370-1907443|CRISPRCasFinder
GCATCAGGGTGTCCTGTCTTCGCGCGCCATCCGCCGCAACGAGCATCGGCTGCATCGGGGTGTCCTGTCTTCGC

>NZ_CP006850|6|6|1907370-1907443|CRISPRCasFinder
GCATCAGGGTGTCCTGTCTTCGC	GCGCCATCCGCCGCAACGAGCATCGGCT
GCATCGGGGTGTCCTGTCTTCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_148306767.1\|1911607_1912234_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483
NZ_CP006850.1\|WP_025348012.1\|1915821_1916667_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|378243
NZ_CP006850.1\|WP_158436171.1\|1920193_1923190_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP006850.1\|WP_025348014.1\|1918000_1918567_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NZ_CP006850.1\|WP_081769167.1\|1916663_1918055_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP006850.1\|WP_081769166.1\|1903301_1903817_-\|DUF4254-domain-containing-protein	unknown	unknown	gnl\|CDD\|379447
NZ_CP006850.1\|WP_025348003.1\|1905324_1905534_+\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP006850.1\|WP_081769165.1\|1901441_1902305_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|307170
NZ_CP006850.1\|WP_051494647.1\|1918550_1920134_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|378189
NZ_CP006850.1\|WP_025348008.1\|1910587_1911379_+\|thioesterase-family-protein	unknown	unknown	gnl\|CDD\|379298
NZ_CP006850.1\|WP_025348001.1\|1903729_1904194_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025348007.1\|1907751_1910550_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380492
NZ_CP006850.1\|WP_025348010.1\|1912230_1913895_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP006850.1\|WP_025348006.1\|1906551_1907244_-\|DUF899-domain-containing-protein	unknown	unknown	gnl\|CDD\|377584
NZ_CP006850.1\|WP_038552379.1\|1904447_1905335_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379262
NZ_CP006850.1\|WP_025348004.1\|1905667_1906009_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|226147
NZ_CP006850.1\|WP_025347997.1\|1900971_1901445_+\|SsrA-binding-protein-SmpB	unknown	unknown	gnl\|CDD\|235455
NZ_CP006850.1\|WP_025348011.1\|1915084_1915825_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NZ_CP006850.1\|WP_025347999.1\|1902829_1903210_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025348005.1\|1906005_1906389_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|377579

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025348012.1\|1915821_1916667_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	2.46828e-31
NZ_CP006850.1\|WP_158436171.1\|1920193_1923190_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	1.5986e-67
NZ_CP006850.1\|WP_025348014.1\|1918000_1918567_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	1.10883e-11
NZ_CP006850.1\|WP_081769167.1\|1916663_1918055_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	7.44689e-56
NZ_CP006850.1\|WP_081769166.1\|1903301_1903817_-\|DUF4254-domain-containing-protein	gnl\|CDD\|379447	pfam14063, DUF4254, Protein of unknown function (DUF4254). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 195 and 207 amino acids in length.	7.19218e-12
NZ_CP006850.1\|WP_025348003.1\|1905324_1905534_+\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	3.71397e-21
NZ_CP006850.1\|WP_081769165.1\|1901441_1902305_+\|DMT-family-transporter	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	5.51945e-05
NZ_CP006850.1\|WP_051494647.1\|1918550_1920134_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.94711e-71
NZ_CP006850.1\|WP_025348008.1\|1910587_1911379_+\|thioesterase-family-protein	gnl\|CDD\|379298	pfam13622, 4HBT_3, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	1.67563e-37
NZ_CP006850.1\|WP_148306767.1\|1911607_1912234_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	1.13637e-10
NZ_CP006850.1\|WP_025348007.1\|1907751_1910550_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380492	cd06268, PBP1_ABC_transporter_LIVBP-like, periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.	2.61721e-07
NZ_CP006850.1\|WP_025348010.1\|1912230_1913895_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.96018e-64
NZ_CP006850.1\|WP_025348006.1\|1906551_1907244_-\|DUF899-domain-containing-protein	gnl\|CDD\|377584	pfam05988, DUF899, Bacterial protein of unknown function (DUF899). This family consists of several uncharacterized bacterial proteins of unknown function.	6.37722e-70
NZ_CP006850.1\|WP_038552379.1\|1904447_1905335_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	5.17467e-08
NZ_CP006850.1\|WP_025348004.1\|1905667_1906009_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|226147	COG3620, COG3620, Predicted transcriptional regulator with C-terminal CBS domains [Transcription].	2.96484e-11
NZ_CP006850.1\|WP_025347997.1\|1900971_1901445_+\|SsrA-binding-protein-SmpB	gnl\|CDD\|235455	PRK05422, smpB, SsrA-binding protein SmpB.	1.29348e-88
NZ_CP006850.1\|WP_025348011.1\|1915084_1915825_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	2.09459e-44
NZ_CP006850.1\|WP_025348005.1\|1906005_1906389_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|377579	pfam05973, Gp49, Phage derived protein Gp49-like (DUF891). This family consists of hypothetical bacterial proteins of unknown function as well as phage Gp49 proteins.	1.78826e-14

>NZ_CP006850.1|WP_025348006.1|1906551_1907244_-|DUF899-domain-containing-protein
MSTPALPPVVDAETWQRELDALRVREKAATRELDAIAAQRRRLPMVEMPEYTLVGEQGPVRLADIFDGKSQLIVYNHMWFPGERWQCPGCTGFTSQFTRLEFLDNWDARFVVVTQGPIDEALAYKRRVGNKMTWYSTADSPFGTDVGAPPGGGFAVNVFLRDGNTVYRTWHTGGRGCEQLGHTFPLIDVLPYGRQEVWQDSPDGWPQSPTYSRWAGSKDIAAAYGEPMNE
>NZ_CP006850.1|WP_025348005.1|1906005_1906389_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MSELFAIEIEPEVRDWLEALPAKHFLKIDEYVGLLAEQAQALSEPYARYLGDGVRELRPTLDGAAIRITYWLAPGRRAILLTVFRKTRMREDAEVKRAKLAQQTCEAEHEPAHQEFIRTIEKGELDR
>NZ_CP006850.1|WP_025348004.1|1905667_1906009_-|helix-turn-helix-domain-containing-protein
MSHARWKTLRERKLAEGYTEPDDVTEARREIQLSMALAKAVYDRRTELGLTQADLAERAGLTQAKISRIEGSDTVPTLPLLAKLADALEATLNIALDAEDTRVNFTSHHTDAA
>NZ_CP006850.1|WP_025348003.1|1905324_1905534_+|DUF397-domain-containing-protein
MNADLSGAHWFTSSHSGGGQECVEVAFLSEGFVGVRDSKDRTGPALIFTPSEWDAFTSAVGTDGFNRSA
>NZ_CP006850.1|WP_038552379.1|1904447_1905335_+|helix-turn-helix-domain-containing-protein
MSVADSTLPRRQLGRHLREGRESIGLTLVEAAKLMQWGKSTLQRLEKGQTEKIRTHDVGLLCEIYQLKTEQTADLVALAEQAAVKNWWQAYGSLISPNFDVYMGLESSAREIFLYQPAAVPGIFQTAEYTRTLDHLFFPDDTEDELTRRVELRLRRQGVITRKKQPAELTAILHEAALRTVVGSPKILAAQLRRLADLSTEPNIQIRVLPFRAGLPVGLSTGPFVILDFGKSPAGDPIEPTVVYAEAFTGAMYFEDDADVDRYRDASRIILRATLDDRASRDLLREMARECGRER
>NZ_CP006850.1|WP_025348001.1|1903729_1904194_-|hypothetical-protein
MEQKAFTDTPASCCVYYRRVCGLPAVVDHDTGRILLRAGVVGAITMPGELGARVRDELAHRRMCPGPTISHVGSGRWSYLCRPDTAAESADMRLFGALFRLNVSIASVGATIALPSPTRASMRYRRWIVAPRNTFRPSLAVTLDAIAACTGGWS
>NZ_CP006850.1|WP_081769166.1|1903301_1903817_-|DUF4254-domain-containing-protein
MDSRAAQHLPAVAGRHTRCDRGVYRRLVVIAIGPTADLPSKYQLLHACRGSVPAGHPLLDGAHRLAVLHARRWSSDRDGVDVVDQARTLLIAELDRWVTGRFPPAHGAASIHTETLGAVIDRLAYYTAAAEAAPNAAELRCLWRKLGELAVAYSDLAAEVRRGVRRLPGCS
>NZ_CP006850.1|WP_025347999.1|1902829_1903210_-|hypothetical-protein
MMRTASLLALPMFAVAAAGCSGNVPWPDKPPTTVPGATGYTIVETVPPTGTETEAGMNTELRARSCRDMLPTLDRLRDNDPAAASKSAEDAIAELSENPEWWSLSQADRDAKAAGIRDAATGQCPG
>NZ_CP006850.1|WP_081769165.1|1901441_1902305_+|DMT-family-transporter
MTAIALALIASIGYGVSDFVGGLASRRVAALRVVIVSYPLSAVILILVAPFAGGGPDAATLWWGAAAGVASGLAVWWFYAALARGPMAVVSPLTAVLSAGVPIVIGLLAGDRPGPAACAGIVCAVVAVVLVSKESPDKVTEEITGGRELRFDRRIAVLTVGSGVAFGLMFVFLHESAATPGLWPVLMSRLSATVVVWVAAMTTGNFHPPRGEPLRLAAYVSVLDVAANVAMLYAFHGSMLSLVSVIGSLYPAATVLLAMVLLGERVGRLQRIGMVLALGSVALIATG
>NZ_CP006850.1|WP_025347997.1|1900971_1901445_+|SsrA-binding-protein-SmpB
MKEKGRKVIATNRKARHNYTILDTYEAGIALVGTEVKSLREGKASLVDAYATIDDGEVWLRGLHIPEYGHGTWTNHSPRRTRKLLLHRREIDKLTGKTKESSQTLVPLSMYFADGKVKVELALAKGKQDYDKRHDLARRTAEREVTRELGRRVKGMR
>NZ_CP006850.1|WP_025348007.1|1907751_1910550_+|amino-acid-ABC-transporter-substrate-binding-protein
MADRERYTRKYLNALRAVAVPDERPRILPTLLRRRKNRRLPPPMVRLIAPDTAEFDRATGLLPRSGEWLAEPGGKRAVPRAVVDAAEAPPDMFDPGFSTDGDRELEEHCLPILHELYLCFGSDDTAMGPIAFPRYRTADWLTRQRLTGSATEASEQLRERLPNLLRRAPAADRSASALGAVGGTLARVLTIVLSLWPVVRLWLFVSSHIPGLSRVSYWFMHQRYLTPRLSHSFIGFGVRLTEPMRRRESSDQIAKLLVNAFLEDLRAAYRRTLWRPSGWRRTAFPVALFDQVRPDDSASRLMRLVNEIRNETGLFDPLVIVARIDGSAESPSARFADLGVTVDGEVRDPLKLWRADIDERRRHRGTDSWYLTLPLPDSLSGELPRFGRSELAYPPAPPWAARRSVVAAVALLPVVALVAVAVVVVQPRLAAGCTPWPWRSGVDVTVRGTECVGLSGSAAQVFSDDPELGEMQREVFHQNVVAERLRHDNPRRPLVTLVYFAGMTYIDRNGRYPHAQAEELAGLAVRQRWANRQSGASEPLLRVVIANGGTTMRYATWVVDHQISRLVRSDPTVIGVVGLDRSSDETRRAIARLGELGMPTMATTLSADGLDQVSPTYFQPVLDNSMQAKLVADYVSGARNPDGSTRYGKVYIYVPDDPGDIYVRTLETDLRQALGPDRVGKVDPWTDQGQIPSRPIPCAPADRGQPADLLFFGGRNPDFGPFVNAVAQHCGAAMPPILANDTATRAVSDKLVQDAAPIGFPVHYVAKGVPALLAGSGCVRDGTPDRSANASPSMFTLCTELTELRHRLPHFQVSWPGDRTGIGFDVAELFLGAVKRNRSRPEYSGAAVNRAAIGLELRRKDLDADTVTGDLSFGGEDGQVKGASIAILMTPDLNNADVPPKCLLQLPLPDDGTNGCPPGTDSDTETWVRPPG
>NZ_CP006850.1|WP_025348008.1|1910587_1911379_+|thioesterase-family-protein
MEAFYHPDPADPSLFHSTELTRGPWSPDAQHAGPPSALLGHVIERCEPRPGFRVGRVAVEILGPVPIEPLRAQARVVRPGRSVELIEATIATERGPVLRANAWRLRVAGPEIEIPVDAIATGAYPGPDTVPAGAEFPSTQPVGFHTGIEYRFVAGSFGAPGPAVCWIRLRYPIVAGTTPSPLERTLAAADSGNGVSAVLDWDRYLFINTDLTVTLHREPAGEWVCLDAVTYPERSGIGMAESRLYDEKGPVGRGTQTLLIGPR
>NZ_CP006850.1|WP_148306767.1|1911607_1912234_+|TetR-family-transcriptional-regulator
MSPIQHDDAPLGLREQKKRRTRIDLCMAARRLTVERGLDATTVDDIAAAVGVSGRTFFNYYETKLDAVVGPVGEIGTPEARQRFIEGGPSGVLIDDLASLYGSSLEPESKAKEAISLVTEIIHSEPRVLAGFVAAGAKQEAAFVELLDERTGGAVSRDFALLAARLMPALTMSAAVSMTEDPDKSLVTALHEQCALAAQLFTSTEESR
>NZ_CP006850.1|WP_025348010.1|1912230_1913895_+|MFS-transporter
MTTTADSPPTPIVLTQKRIWLIFSALIAGMFLASLDQTIVGTAMPTIVGDLGGVSHMAWTATSYLLATTIVMPIYGKFGDMFGRRWLFLFAIAVFTAASVGAAASTSFWEFVVFRGLQGVGGGGLMILAQAIIADVVPAKDRGKYMAPMGAIFGITSVAGPLLGGFFADQLGWQWCFWLNVPIGLAALFIAARYLSIPSHRPKTRPDYLGIVLMSSATTLLILITDWGGKQYAWGSAVMVSMIVALVLVIGAFIAVEANAEEPMLPLWLFRNRTFVLTSAIGLIVGLSMFAALAFIPTYLQMATGASASVSGLLLIPMMVGMMITLIGSMSIITKTGRYRVFPPAGALVIIGGMLWLTRLDAQSSMWLVSAMLFVMGAGLGLIMQIIVLVVQNAVAPDQIGTATSANNYFREMGGAIGVAIFGSIFTNRLTDGLTDVFRTHLPEVMAAHLDPSSLVPSVVKHLPDGLHDAIVGSYVDALVPGFWYLIPAAALAFLLALFIPHMTLSDEAGMIARGEAVMADEGSTGTDAAQRDSAPGRPADQDSAQDPDPQPVR
>NZ_CP006850.1|WP_025348011.1|1915084_1915825_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MTTSPDNGSAAARFVTTHSILTLDARHPFVLKSLHDAQDMHRTVMSGFLGWVEDGQPEARKLMGVLSTWSLNLRESTLIIVVQANVPADWSRIPSNAMKDKPHTITVDKTIRTGNTYTFRTVVNPTRDRNTPKSIAEPGTRTRKRTPHQTPKWAESWFTDRLQPPGEPPIAPSGTRRIGATTDPNTLTVRMLPTVSSSGAHPGLRIIRAELKGTLTVTDPKTFVEALHTGIGRARAYSAGLLLIRD
>NZ_CP006850.1|WP_025348012.1|1915821_1916667_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTDATESSVLLIRLAAPLQSWGSLSRFAHRSTDLHPTKSGVIGMLAAALGLDRADPLDTLTELRFGVRADCPGVPVRDYHAVGGGAYPLRPRDLILDHRRATRAAPSTDTGDESEFGDYTLEKWYGAPKYVIRDPESGALITQTQAVSRDAMITTRWYLSDAKFVAAVEHSDNTFLEHLAAALEQPQRLLWLGRKSCPPSGELAGGVHPGTLESVLETTALLPGADPRPWAWIETTPGTPGAAPVADQPLSFLADQRTHATRWETRIRLTPRPDIEWTLIP
>NZ_CP006850.1|WP_081769167.1|1916663_1918055_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MDPRLLHPQPHQVRSQEVTDPRPQYLSLHLLETVAAALPVRDENGRAKTIVFGGEERNMITSQARRRAERTHSRRRANTNQGPLAGYTMGLRTREWALRISDALVANHQWNKDEALGTARACLEAVGLKFGDKPTTINLTKVLLFAPENTGTVIAADLDAHRVLAAEWFTEYASAKEANSKAADKRRPRRRTAQSEDTDIETQPEPEAGKQDLPRLPKEIRTAILTALAPRDAIDIALYGRFLAEIPDSPNVDGAIQTAHAFTVHAAEQIDDFYAAADDAKLDRKANALDFLDSAEDGGAGMTGYQSLISGTFYRHAALDRRKLRANLRAAGMNEDESDEAALAAEAEFIESFVNAFPDAKRNSTASTGTLPNVVLASDGARPFNYAATFENPVNPAKEGSVALAAAQRLLAHHDLVGRKRPDINPGKVLTYDLDITELLAEYAKAGELPCAEVDTLEELISR
>NZ_CP006850.1|WP_025348014.1|1918000_1918567_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTATNDTSDAETPPAEHEQRQPADRLTRWLGGLVRRHDLGALADLRRPKTALTQSHFLAMSYAPSASDDEVYRLVAFLFARYHAGASLPSYGRGNLGTALRKVGSGAVRGPEDPGADRLMARISASRAIPERHLQHAIERMRAGDTAPPSWSMLVDDLSRWTDHGRPAAFEWTRDFYTPNRTKYGAKK
>NZ_CP006850.1|WP_051494647.1|1918550_1920134_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MHVRQVPDSIRVPTPRWDPRTEACIAVLTSDGHATTLGLADVLHQADDLQAIFGTTPGEVVAVVEYLLGICYAAKVHPGTVREWRKWVSGRHSLDTAAQWLLAQPDDAWNIFDPHKPLGQNAMLAPFLDEHGSGPAQLVLEHAGDYNQFFDHHHLEHPTPLSPAEAFRAMLVQHVYGPGLRGRVSGDLLGPKLNNLATGRLATRMRVLALGETVGDTLRLNLQQYESDGPDYFNTTWTQRGRRDFAHKPSGRMPDGPADLHTVLGRSILLRPSRNEDGALCVDRVIVGAGELLVPLPAEFRQDAVLVPRAKGEFSPLRPDVNKALWREAHALYAAVAENKKGTDLYSRLAELSGFRVRLWAVGLAIENNKLLTWLADSFPWVSGREIELYHAARNGSRAAEYVGIALGRAAEIAQRSTYPGAGSDQKGTLSSRFDTRTEHFAAAAAPFHRLLEATADGTTAAEATDEFARTLVDTARRLLANRLRSLPSNSRGLRARAAAENKLHTELTHSKAPISVREAADDDRDQ
>NZ_CP006850.1|WP_158436171.1|1920193_1923190_+|CRISPR-associated-helicase-Cas3'
MADVRIDQFAGGYPWAKTDTEGISRAAGGPAWDPLVAHMLDVAAVVFELWDRYLSLSVRNRLAESFGDGNDEHARVMVAFLVALHDLGKASDCFLDQFGTGRAKRNGLDRERAVWEKMARAADLPLAEDMSRVHWARHEHITAAHLARILGCECFECGGTGTEYEDLHVVAMLLAGHHGHIPDKHTVDVAYGAAAPAVWGATHSELAALIADTLGVDLSQVKEKIRFARSASLTLFAGFVVLADWVASSQTWFHYRESASSIESCWEKSQSEAAAAVTALRLARWQPPALTWSDLWPGTEPRGFQQAVIDLLPNRGPALAIIESDTGSGKTRAALWCAYHLARTCGYTGLYMAMPTRAATNQIAVELRAFIAATLNDADSVNFAVVHGTAQATDIVHDLLDAARADGQELDDLSSSIEPGLIGDADPAGLGRVVLDPWYLRRCLGLVSPFGIGTVDQLVLAVQRSSHWFLRMLGLACKTVIIDEAHAYELYQQQLLESAVAWLADAGASVVVLSATLPTSVREALTNAWCRGHRTEVEDAGQSGPITMVDAAGRVRRGGPVETPPELHTVVTLDEDPGIAQLAARLVERVEHGGVAAVIRTRVSSAVDLHAAVVEQAKERGWPAEKNLPPKDIILLHGRMMPRDRLPIEQRLVKLTGLGTDRGQRNPQRPQRLIVIATQVIEQSLDVDFDWIVTDLAPIDLLIQRRGRLHRHQINDSLRAPQFATSRMSVLVRVHNQLPIVEPPDENNRRPGTLDALVYAPYTLAATWEALQSRRGHCSCERCAIDNSDAIHLVTPNDSATLIESVYGAEPRAAGELGQLLDRTWNQWKMALNTEQAEASARAVNPYKCNMTPIGVAELASGAGHGDGEEGGAAGIRSRSRLGDESFTAVLLYRQNDGTLTYDNAGSLLADLKSHNPTRSKRETEARRRQQSDILLNTISIPARWIGPRRIPKPETWRPVTEYGPFAKLHVVELNTDGKCINEPHKVVYSSTRGIEMR

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Crispr_ID: NZ_CP006850_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_7

1923400-1923489

TypeI-E

I-E

Consensus_repeat	Method
GGACCATCCCCGCGTGCGCGGGGAGCAC	CRISPRCasFinder

1 spacers

cas3,cas8e,cse2gr11,cas7,cas5,cas6e

The CRISPR arrays of NZ_CP006850_7

>merge|NZ_CP006850|7|1923400-1923489|CRISPRCasFinder
GGGCTATCCCTGCGTACGCGGGGAGCACTCGAATTCGCCGGTCGCCGGACAGGTTCCGGTGGAACCATCCCCGCATGCGCGGGGAGCACA

>NZ_CP006850|7|7|1923400-1923489|CRISPRCasFinder
GGGCTATCCCTGCGTACGCGGGGAGCAC	TCGAATTCGCCGGTCGCCGGACAGGTTCCGGTG
GAACCATCCCCGCATGCGCGGGGAGCACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025348019.1\|1925843_1926152_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025348012.1\|1915821_1916667_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|378243
NZ_CP006850.1\|WP_025348023.1\|1929464_1929938_-\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NZ_CP006850.1\|WP_038550368.1\|1930079_1930814_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197666
NZ_CP006850.1\|WP_025348014.1\|1918000_1918567_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NZ_CP006850.1\|WP_081769170.1\|1928785_1929448_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP006850.1\|WP_025348021.1\|1927794_1928757_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225242
NZ_CP006850.1\|WP_025348020.1\|1926840_1927602_-\|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|187629
NZ_CP006850.1\|WP_051494647.1\|1918550_1920134_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|378189
NZ_CP006850.1\|WP_025348008.1\|1910587_1911379_+\|thioesterase-family-protein	unknown	unknown	gnl\|CDD\|379298
NZ_CP006850.1\|WP_148306767.1\|1911607_1912234_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483
NZ_CP006850.1\|WP_025348007.1\|1907751_1910550_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380492
NZ_CP006850.1\|WP_025348010.1\|1912230_1913895_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP006850.1\|WP_081769167.1\|1916663_1918055_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP006850.1\|WP_158436171.1\|1920193_1923190_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP006850.1\|WP_081769169.1\|1924693_1925578_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379262
NZ_CP006850.1\|WP_025348025.1\|1930795_1931188_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319901
NZ_CP006850.1\|WP_025348026.1\|1931406_1932411_+\|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|378890
NZ_CP006850.1\|WP_025348011.1\|1915084_1915825_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NZ_CP006850.1\|WP_025348017.1\|1924490_1924688_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025348012.1\|1915821_1916667_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	2.46828e-31
NZ_CP006850.1\|WP_025348023.1\|1929464_1929938_-\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	3.7908e-41
NZ_CP006850.1\|WP_038550368.1\|1930079_1930814_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.35484e-12
NZ_CP006850.1\|WP_025348014.1\|1918000_1918567_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	1.10883e-11
NZ_CP006850.1\|WP_081769170.1\|1928785_1929448_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	1.20377e-09
NZ_CP006850.1\|WP_025348021.1\|1927794_1928757_-\|hypothetical-protein	gnl\|CDD\|225242	COG2367, PenP, Beta-lactamase class A [Defense mechanisms].	1.61061e-06
NZ_CP006850.1\|WP_025348020.1\|1926840_1927602_-\|3-hydroxyacyl-CoA-dehydrogenase	gnl\|CDD\|187629	cd05371, HSD10-like_SDR_c, 17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs. HSD10, also known as amyloid-peptide-binding alcohol dehydrogenase (ABAD), was previously identified as a L-3-hydroxyacyl-CoA dehydrogenase, HADH2. In fatty acid metabolism, HADH2 catalyzes the third step of beta-oxidation, the conversion of a hydroxyl to a keto group in the NAD-dependent oxidation of L-3-hydroxyacyl CoA. In addition to alcohol dehydrogenase and HADH2 activites, HSD10 has steroid dehydrogenase activity. Although the mechanism is unclear, HSD10 is implicated in the formation of amyloid beta-petide in the brain (which is linked to the development of Alzheimer's disease). Although HSD10 is normally concentrated in the mitochondria, in the presence of amyloid beta-peptide it translocates into the plasma membrane, where it's action may generate cytotoxic aldehydes and may lower estrogen levels through its use of 17-beta-estradiol as a substrate. HSD10 is a member of the SRD family, but differs from other SDRs by the presence of two insertions of unknown function. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	7.46699e-133
NZ_CP006850.1\|WP_051494647.1\|1918550_1920134_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.94711e-71
NZ_CP006850.1\|WP_025348008.1\|1910587_1911379_+\|thioesterase-family-protein	gnl\|CDD\|379298	pfam13622, 4HBT_3, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	1.67563e-37
NZ_CP006850.1\|WP_148306767.1\|1911607_1912234_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	1.13637e-10
NZ_CP006850.1\|WP_025348007.1\|1907751_1910550_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380492	cd06268, PBP1_ABC_transporter_LIVBP-like, periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.	2.61721e-07
NZ_CP006850.1\|WP_025348010.1\|1912230_1913895_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.96018e-64
NZ_CP006850.1\|WP_081769167.1\|1916663_1918055_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	7.44689e-56
NZ_CP006850.1\|WP_158436171.1\|1920193_1923190_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	1.5986e-67
NZ_CP006850.1\|WP_081769169.1\|1924693_1925578_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.91525e-10
NZ_CP006850.1\|WP_025348025.1\|1930795_1931188_-\|VOC-family-protein	gnl\|CDD\|319901	cd07235, MRD, Mitomycin C resistance protein (MRD). Mitomycin C (MC) is a naturally occurring antibiotic, and antitumor agent used in the treatment of cancer. Its antitumor activity is exerted primarily through monofunctional and bifunctional alkylation of DNA. MRD binds to MC and functions as a component of the MC exporting system. MC is bound to MRD by a stacking interaction between a His and a Trp. MRD adopts a structural fold similar to bleomycin resistance protein, glyoxalase I, and extradiol dioxygenases; and it has binding sites at an identical location to binding sites in these evolutionarily related enzymes.	2.64281e-40
NZ_CP006850.1\|WP_025348026.1\|1931406_1932411_+\|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein	gnl\|CDD\|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	5.64217e-19
NZ_CP006850.1\|WP_025348011.1\|1915084_1915825_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	2.09459e-44
NZ_CP006850.1\|WP_025348017.1\|1924490_1924688_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	4.72502e-17

>NZ_CP006850.1|WP_158436171.1|1920193_1923190_+|CRISPR-associated-helicase-Cas3'
MADVRIDQFAGGYPWAKTDTEGISRAAGGPAWDPLVAHMLDVAAVVFELWDRYLSLSVRNRLAESFGDGNDEHARVMVAFLVALHDLGKASDCFLDQFGTGRAKRNGLDRERAVWEKMARAADLPLAEDMSRVHWARHEHITAAHLARILGCECFECGGTGTEYEDLHVVAMLLAGHHGHIPDKHTVDVAYGAAAPAVWGATHSELAALIADTLGVDLSQVKEKIRFARSASLTLFAGFVVLADWVASSQTWFHYRESASSIESCWEKSQSEAAAAVTALRLARWQPPALTWSDLWPGTEPRGFQQAVIDLLPNRGPALAIIESDTGSGKTRAALWCAYHLARTCGYTGLYMAMPTRAATNQIAVELRAFIAATLNDADSVNFAVVHGTAQATDIVHDLLDAARADGQELDDLSSSIEPGLIGDADPAGLGRVVLDPWYLRRCLGLVSPFGIGTVDQLVLAVQRSSHWFLRMLGLACKTVIIDEAHAYELYQQQLLESAVAWLADAGASVVVLSATLPTSVREALTNAWCRGHRTEVEDAGQSGPITMVDAAGRVRRGGPVETPPELHTVVTLDEDPGIAQLAARLVERVEHGGVAAVIRTRVSSAVDLHAAVVEQAKERGWPAEKNLPPKDIILLHGRMMPRDRLPIEQRLVKLTGLGTDRGQRNPQRPQRLIVIATQVIEQSLDVDFDWIVTDLAPIDLLIQRRGRLHRHQINDSLRAPQFATSRMSVLVRVHNQLPIVEPPDENNRRPGTLDALVYAPYTLAATWEALQSRRGHCSCERCAIDNSDAIHLVTPNDSATLIESVYGAEPRAAGELGQLLDRTWNQWKMALNTEQAEASARAVNPYKCNMTPIGVAELASGAGHGDGEEGGAAGIRSRSRLGDESFTAVLLYRQNDGTLTYDNAGSLLADLKSHNPTRSKRETEARRRQQSDILLNTISIPARWIGPRRIPKPETWRPVTEYGPFAKLHVVELNTDGKCINEPHKVVYSSTRGIEMR
>NZ_CP006850.1|WP_051494647.1|1918550_1920134_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MHVRQVPDSIRVPTPRWDPRTEACIAVLTSDGHATTLGLADVLHQADDLQAIFGTTPGEVVAVVEYLLGICYAAKVHPGTVREWRKWVSGRHSLDTAAQWLLAQPDDAWNIFDPHKPLGQNAMLAPFLDEHGSGPAQLVLEHAGDYNQFFDHHHLEHPTPLSPAEAFRAMLVQHVYGPGLRGRVSGDLLGPKLNNLATGRLATRMRVLALGETVGDTLRLNLQQYESDGPDYFNTTWTQRGRRDFAHKPSGRMPDGPADLHTVLGRSILLRPSRNEDGALCVDRVIVGAGELLVPLPAEFRQDAVLVPRAKGEFSPLRPDVNKALWREAHALYAAVAENKKGTDLYSRLAELSGFRVRLWAVGLAIENNKLLTWLADSFPWVSGREIELYHAARNGSRAAEYVGIALGRAAEIAQRSTYPGAGSDQKGTLSSRFDTRTEHFAAAAAPFHRLLEATADGTTAAEATDEFARTLVDTARRLLANRLRSLPSNSRGLRARAAAENKLHTELTHSKAPISVREAADDDRDQ
>NZ_CP006850.1|WP_025348014.1|1918000_1918567_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTATNDTSDAETPPAEHEQRQPADRLTRWLGGLVRRHDLGALADLRRPKTALTQSHFLAMSYAPSASDDEVYRLVAFLFARYHAGASLPSYGRGNLGTALRKVGSGAVRGPEDPGADRLMARISASRAIPERHLQHAIERMRAGDTAPPSWSMLVDDLSRWTDHGRPAAFEWTRDFYTPNRTKYGAKK
>NZ_CP006850.1|WP_081769167.1|1916663_1918055_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MDPRLLHPQPHQVRSQEVTDPRPQYLSLHLLETVAAALPVRDENGRAKTIVFGGEERNMITSQARRRAERTHSRRRANTNQGPLAGYTMGLRTREWALRISDALVANHQWNKDEALGTARACLEAVGLKFGDKPTTINLTKVLLFAPENTGTVIAADLDAHRVLAAEWFTEYASAKEANSKAADKRRPRRRTAQSEDTDIETQPEPEAGKQDLPRLPKEIRTAILTALAPRDAIDIALYGRFLAEIPDSPNVDGAIQTAHAFTVHAAEQIDDFYAAADDAKLDRKANALDFLDSAEDGGAGMTGYQSLISGTFYRHAALDRRKLRANLRAAGMNEDESDEAALAAEAEFIESFVNAFPDAKRNSTASTGTLPNVVLASDGARPFNYAATFENPVNPAKEGSVALAAAQRLLAHHDLVGRKRPDINPGKVLTYDLDITELLAEYAKAGELPCAEVDTLEELISR
>NZ_CP006850.1|WP_025348012.1|1915821_1916667_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTDATESSVLLIRLAAPLQSWGSLSRFAHRSTDLHPTKSGVIGMLAAALGLDRADPLDTLTELRFGVRADCPGVPVRDYHAVGGGAYPLRPRDLILDHRRATRAAPSTDTGDESEFGDYTLEKWYGAPKYVIRDPESGALITQTQAVSRDAMITTRWYLSDAKFVAAVEHSDNTFLEHLAAALEQPQRLLWLGRKSCPPSGELAGGVHPGTLESVLETTALLPGADPRPWAWIETTPGTPGAAPVADQPLSFLADQRTHATRWETRIRLTPRPDIEWTLIP
>NZ_CP006850.1|WP_025348011.1|1915084_1915825_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MTTSPDNGSAAARFVTTHSILTLDARHPFVLKSLHDAQDMHRTVMSGFLGWVEDGQPEARKLMGVLSTWSLNLRESTLIIVVQANVPADWSRIPSNAMKDKPHTITVDKTIRTGNTYTFRTVVNPTRDRNTPKSIAEPGTRTRKRTPHQTPKWAESWFTDRLQPPGEPPIAPSGTRRIGATTDPNTLTVRMLPTVSSSGAHPGLRIIRAELKGTLTVTDPKTFVEALHTGIGRARAYSAGLLLIRD
>NZ_CP006850.1|WP_025348010.1|1912230_1913895_+|MFS-transporter
MTTTADSPPTPIVLTQKRIWLIFSALIAGMFLASLDQTIVGTAMPTIVGDLGGVSHMAWTATSYLLATTIVMPIYGKFGDMFGRRWLFLFAIAVFTAASVGAAASTSFWEFVVFRGLQGVGGGGLMILAQAIIADVVPAKDRGKYMAPMGAIFGITSVAGPLLGGFFADQLGWQWCFWLNVPIGLAALFIAARYLSIPSHRPKTRPDYLGIVLMSSATTLLILITDWGGKQYAWGSAVMVSMIVALVLVIGAFIAVEANAEEPMLPLWLFRNRTFVLTSAIGLIVGLSMFAALAFIPTYLQMATGASASVSGLLLIPMMVGMMITLIGSMSIITKTGRYRVFPPAGALVIIGGMLWLTRLDAQSSMWLVSAMLFVMGAGLGLIMQIIVLVVQNAVAPDQIGTATSANNYFREMGGAIGVAIFGSIFTNRLTDGLTDVFRTHLPEVMAAHLDPSSLVPSVVKHLPDGLHDAIVGSYVDALVPGFWYLIPAAALAFLLALFIPHMTLSDEAGMIARGEAVMADEGSTGTDAAQRDSAPGRPADQDSAQDPDPQPVR
>NZ_CP006850.1|WP_148306767.1|1911607_1912234_+|TetR-family-transcriptional-regulator
MSPIQHDDAPLGLREQKKRRTRIDLCMAARRLTVERGLDATTVDDIAAAVGVSGRTFFNYYETKLDAVVGPVGEIGTPEARQRFIEGGPSGVLIDDLASLYGSSLEPESKAKEAISLVTEIIHSEPRVLAGFVAAGAKQEAAFVELLDERTGGAVSRDFALLAARLMPALTMSAAVSMTEDPDKSLVTALHEQCALAAQLFTSTEESR
>NZ_CP006850.1|WP_025348008.1|1910587_1911379_+|thioesterase-family-protein
MEAFYHPDPADPSLFHSTELTRGPWSPDAQHAGPPSALLGHVIERCEPRPGFRVGRVAVEILGPVPIEPLRAQARVVRPGRSVELIEATIATERGPVLRANAWRLRVAGPEIEIPVDAIATGAYPGPDTVPAGAEFPSTQPVGFHTGIEYRFVAGSFGAPGPAVCWIRLRYPIVAGTTPSPLERTLAAADSGNGVSAVLDWDRYLFINTDLTVTLHREPAGEWVCLDAVTYPERSGIGMAESRLYDEKGPVGRGTQTLLIGPR
>NZ_CP006850.1|WP_025348007.1|1907751_1910550_+|amino-acid-ABC-transporter-substrate-binding-protein
MADRERYTRKYLNALRAVAVPDERPRILPTLLRRRKNRRLPPPMVRLIAPDTAEFDRATGLLPRSGEWLAEPGGKRAVPRAVVDAAEAPPDMFDPGFSTDGDRELEEHCLPILHELYLCFGSDDTAMGPIAFPRYRTADWLTRQRLTGSATEASEQLRERLPNLLRRAPAADRSASALGAVGGTLARVLTIVLSLWPVVRLWLFVSSHIPGLSRVSYWFMHQRYLTPRLSHSFIGFGVRLTEPMRRRESSDQIAKLLVNAFLEDLRAAYRRTLWRPSGWRRTAFPVALFDQVRPDDSASRLMRLVNEIRNETGLFDPLVIVARIDGSAESPSARFADLGVTVDGEVRDPLKLWRADIDERRRHRGTDSWYLTLPLPDSLSGELPRFGRSELAYPPAPPWAARRSVVAAVALLPVVALVAVAVVVVQPRLAAGCTPWPWRSGVDVTVRGTECVGLSGSAAQVFSDDPELGEMQREVFHQNVVAERLRHDNPRRPLVTLVYFAGMTYIDRNGRYPHAQAEELAGLAVRQRWANRQSGASEPLLRVVIANGGTTMRYATWVVDHQISRLVRSDPTVIGVVGLDRSSDETRRAIARLGELGMPTMATTLSADGLDQVSPTYFQPVLDNSMQAKLVADYVSGARNPDGSTRYGKVYIYVPDDPGDIYVRTLETDLRQALGPDRVGKVDPWTDQGQIPSRPIPCAPADRGQPADLLFFGGRNPDFGPFVNAVAQHCGAAMPPILANDTATRAVSDKLVQDAAPIGFPVHYVAKGVPALLAGSGCVRDGTPDRSANASPSMFTLCTELTELRHRLPHFQVSWPGDRTGIGFDVAELFLGAVKRNRSRPEYSGAAVNRAAIGLELRRKDLDADTVTGDLSFGGEDGQVKGASIAILMTPDLNNADVPPKCLLQLPLPDDGTNGCPPGTDSDTETWVRPPG
>NZ_CP006850.1|WP_025348017.1|1924490_1924688_-|DUF397-domain-containing-protein
MGADLSGAKWFKSTRSVGARECVEVAHLDGGAVGVRDSKNIPGPALVFSGTDWDAFLADIENLSI
>NZ_CP006850.1|WP_081769169.1|1924693_1925578_-|helix-turn-helix-domain-containing-protein
MAGGSTLPRRALGRQLKAFRERKGLSQGASARIMETSPQTYGRLEEGRTTKVTDLALNALADAFGCDNNERRLLLDLAQEIRTASKDKRGWWRSLADAIPMDFNHYLSLEEAAEREFSWQTTIIPGLLHTTDYRREVTWAAHPQSSPEEIERIGDITTRRQDLLTRDGFRFEPYILESVLYGQVGSPAVMGEQLGRLLELSELPNVDIRIVPLKARHPIGLVARSFVYLEFPPLPSSGMGEPPVVYIEGLVGGLYLESDPEVGKYSDVVRQLQAVALSESESRDLISAAESDWR
>NZ_CP006850.1|WP_025348019.1|1925843_1926152_+|hypothetical-protein
MRTRPTAFGWVDYDTSLAPQWDSAQVSRLARRLGYEILWTPTSLIPLVDQVRAADVDAVIAPSTEHIDILTLNNLMSIVNVEIVLPRLSFSKWGALPPRRHG
>NZ_CP006850.1|WP_025348020.1|1926840_1927602_-|3-hydroxyacyl-CoA-dehydrogenase
MKLENAVAVVTGGASGLGLATVKELHSQGAKVVIIDLPSSNGESIAKELGDGVVFAATDVTNEEQVSAALDAAQALGTLRIAVNCAGIGNAIKTVSKKGAFPLADFTKIINVNLIGTFNVIRLAAERIAATELDGEERGVIINTASVAAYDGQIGQAAYSASKGGIVGLTLPVARDLASLNIRVNTIAPGLFHTPLFESLPEEAIKALGAQVPHPARLGNPTEYAALARHIVENPMLNGETIRLDGAIRMAPR
>NZ_CP006850.1|WP_025348021.1|1927794_1928757_-|hypothetical-protein
MKYPSRRTRVLGAAVATAFVIAAFTTGCTAVTAQAHPAASVHNATPAIVAAQRISPDDLAQQMQQAVENAEPGSEVGIDVVDTASGATLAGLDTDQQFYTASVVKLLIALDTMRSAGWQPDSETTATLSTMLSASDDDIADALWDDDGGPQIVSRMAATIGLPDTTPPDDPEQWGETRTTPADVVRIYDYITTDVPSPARDIVLTALGGTTEIAADGTDQYFGIPDGLPGTGWDVKQGWMTLDDSTTIDTTGLVSAGAQSGRYVVVVLTTQPPGIDWTAGGAAVTAAVGALRPALVPNTSAGTVSAETVTCSSICPASGK
>NZ_CP006850.1|WP_081769170.1|1928785_1929448_+|TetR/AcrR-family-transcriptional-regulator
MARGHVGRSLSVRRACWWTRPAVLGHDRTVTKSGYHHGDLRETLLRAAAEQIAAEGVDTVSLRALAQRAGVSHAAPAHHFGNRQGLLTALAIRGFELLADELRAARDDFREMAVAYIGFARRHPGHFDVMFRHDLLRADDPDLIAARVTSGAELRSGVAQLGVADEARPATELAAWSLVHGFASLWREGALTDSDLGGVDPEQLARQMVATVEFVGAKKV
>NZ_CP006850.1|WP_025348023.1|1929464_1929938_-|large-conductance-mechanosensitive-channel-protein-MscL
MLKGFKDFLMRGNVIELAVAVVMGTAFTAIVTSVTKGIVEPLLAVVGTNGQLGLGIQLVADKPATFIAVGPIVSAGINFIMVAAVLYFVLMLPMTTLQKRFSKKKKSEPTQTELLIEIRDLLATQKTSHTNDSHTTDTRAHRDAHPQRHASEMVHEH
>NZ_CP006850.1|WP_038550368.1|1930079_1930814_+|helix-turn-helix-domain-containing-protein
MSDRAPAPYLERPARTCADAVVWRRRVGAGPVTVLPDGCMDLLWLGGRLVVAGPDTRAQHSAAVPETAVHGIRFAPGTAPALLGVVAPELLDQRVELAQLWPARRVRHLADLVAAAPDPAAGLEEIARRCAEAAGPPDPVLAQIVRRLDAGAPVAATADALGLGARRLHRISVSAFGYGPKMLARVLRMRRALDLARSDIGFADAAALAGYADQAHMTRDIRALTGRSPGRVIGSPRAAQPSGA
>NZ_CP006850.1|WP_025348025.1|1930795_1931188_-|VOC-family-protein
MAPELNAIGVVVSDLTAALGFYRRLGLEFGDIMGGGHVEAALPGGFRFMLDSEDNIAADVGSGREWNAASGRIGLAVGCASPAEVDAVFAELVAAGYHGETAPFDAVWGQRYATVHDPDGNSVDLYAPLG
>NZ_CP006850.1|WP_025348026.1|1931406_1932411_+|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein
MATDQTMLHRFVISQMSDAGIDRVRLLRECELPEWTLAGEGVHVPSRIFSRLWELGEKWLDDPDVALHVASRYQLAATRLYDYLFASAPTVGAGLATCGPYVTAVTTNHRFDLVTEGAETTLFLDMIDGEGRGRELVQMWGLVAVLTRTRRVLATSLDPVRVSLRQAAPRRLGAFTEVFGTAVLEFGADADSMTFRTLDMDLPLTTADPVLAEVLQPLAAALPPPPPLISAWPERVAKALADAFSEGEVSLDQVARRLVISPRTLQRRLAESGTTWRRELDRARLARAAAAGPVSRARQAELLGYADAGSMRRAAQRWSMVAHSRPVGPAGCQA

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Crispr_ID: NZ_CP006850_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_8

1923709-1924042

TypeI-E

I-E

Consensus_repeat	Method
GGACCATCCCCGCGTGCGCGGGGAGCAC	CRISPRCasFinder
GGACCATCCCCGCGTGCGCGGGGAGCAC	CRT
GGACCATCCCCGCGTGCGCGGGGAGCACG	PILER-CR

5 spacers

cas3,cas8e,cse2gr11,cas7,cas5,cas6e

The CRISPR arrays of NZ_CP006850_8

>merge|NZ_CP006850|8|1923709-1924042|CRISPRCasFinder,CRT,PILER-CR
CGACAATCCCCGCGTGCGCGGGGAACACCCGCCCATGACGATCGCCTCGTCTCGCGCACATGGACCATCCCCGCGTGCGCGGGAAGCACCGCAGCGCGGTCAGCGTCAGGTCATGATCGAGCGGACCATCCCCGCGTGCGCGGGGAGCACGCTGGGCCTGGACCTGATCCGCCTGCACCGCACCGGACCATCCCCGCGTGCGCGGGGAGCACGAGCACGATTGGCCTCGGCCGCTGCGGGTCGGGGGACCATCCCCGCGTGCGCGGGGAGCACGGATCCGGTGCAGCAGTCGATCGCGCTCCAAAAGGACCATCCCCGCGTGCGCGGGGAGCAC

>NZ_CP006850|8|8|1923709-1924042|CRISPRCasFinder
CGACAATCCCCGCGTGCGCGGGGAACAC	CCGCCCATGACGATCGCCTCGTCTCGCGCACAT
GGACCATCCCCGCGTGCGCGGGAAGCAC	CGCAGCGCGGTCAGCGTCAGGTCATGATCGAGC
GGACCATCCCCGCGTGCGCGGGGAGCAC	GCTGGGCCTGGACCTGATCCGCCTGCACCGCACC
GGACCATCCCCGCGTGCGCGGGGAGCAC	GAGCACGATTGGCCTCGGCCGCTGCGGGTCGGG
GGACCATCCCCGCGTGCGCGGGGAGCAC	GGATCCGGTGCAGCAGTCGATCGCGCTCCAAAA
GGACCATCCCCGCGTGCGCGGGGAGCAC

>NZ_CP006850|8|1|1923709-1924042|CRT
CGACAATCCCCGCGTGCGCGGGGAACAC	CCGCCCATGACGATCGCCTCGTCTCGCGCACAT
GGACCATCCCCGCGTGCGCGGGAAGCAC	CGCAGCGCGGTCAGCGTCAGGTCATGATCGAGC
GGACCATCCCCGCGTGCGCGGGGAGCAC	GCTGGGCCTGGACCTGATCCGCCTGCACCGCACC
GGACCATCCCCGCGTGCGCGGGGAGCAC	GAGCACGATTGGCCTCGGCCGCTGCGGGTCGGG
GGACCATCCCCGCGTGCGCGGGGAGCAC	GGATCCGGTGCAGCAGTCGATCGCGCTCCAAAA
GGACCATCCCCGCGTGCGCGGGGAGCAC

>NZ_CP006850|8|1|1923770-1923982|PILER-CR
GGACCATCCCCGCGTGCGCGGGAAGCACC	GCAGCGCGGTCAGCGTCAGGTCATGATCGAGC
GGACCATCCCCGCGTGCGCGGGGAGCACG	CTGGGCCTGGACCTGATCCGCCTGCACCGCACC
GGACCATCCCCGCGTGCGCGGGGAGCACG	AGCACGATTGGCCTCGGCCGCTGCGGGTCGGG
GGACCATCCCCGCGTGCGCGGGGAGCACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025348019.1\|1925843_1926152_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025348012.1\|1915821_1916667_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|378243
NZ_CP006850.1\|WP_025348023.1\|1929464_1929938_-\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NZ_CP006850.1\|WP_038550368.1\|1930079_1930814_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197666
NZ_CP006850.1\|WP_025348014.1\|1918000_1918567_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NZ_CP006850.1\|WP_081769170.1\|1928785_1929448_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP006850.1\|WP_025348021.1\|1927794_1928757_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225242
NZ_CP006850.1\|WP_025348020.1\|1926840_1927602_-\|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|187629
NZ_CP006850.1\|WP_051494647.1\|1918550_1920134_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|378189
NZ_CP006850.1\|WP_025348008.1\|1910587_1911379_+\|thioesterase-family-protein	unknown	unknown	gnl\|CDD\|379298
NZ_CP006850.1\|WP_148306767.1\|1911607_1912234_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483
NZ_CP006850.1\|WP_025348007.1\|1907751_1910550_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380492
NZ_CP006850.1\|WP_025348010.1\|1912230_1913895_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP006850.1\|WP_081769167.1\|1916663_1918055_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP006850.1\|WP_158436171.1\|1920193_1923190_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP006850.1\|WP_081769169.1\|1924693_1925578_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379262
NZ_CP006850.1\|WP_025348025.1\|1930795_1931188_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319901
NZ_CP006850.1\|WP_025348026.1\|1931406_1932411_+\|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|378890
NZ_CP006850.1\|WP_025348011.1\|1915084_1915825_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NZ_CP006850.1\|WP_025348017.1\|1924490_1924688_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025348012.1\|1915821_1916667_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	2.46828e-31
NZ_CP006850.1\|WP_025348023.1\|1929464_1929938_-\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	3.7908e-41
NZ_CP006850.1\|WP_038550368.1\|1930079_1930814_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.35484e-12
NZ_CP006850.1\|WP_025348014.1\|1918000_1918567_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	1.10883e-11
NZ_CP006850.1\|WP_081769170.1\|1928785_1929448_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	1.20377e-09
NZ_CP006850.1\|WP_025348021.1\|1927794_1928757_-\|hypothetical-protein	gnl\|CDD\|225242	COG2367, PenP, Beta-lactamase class A [Defense mechanisms].	1.61061e-06
NZ_CP006850.1\|WP_025348020.1\|1926840_1927602_-\|3-hydroxyacyl-CoA-dehydrogenase	gnl\|CDD\|187629	cd05371, HSD10-like_SDR_c, 17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs. HSD10, also known as amyloid-peptide-binding alcohol dehydrogenase (ABAD), was previously identified as a L-3-hydroxyacyl-CoA dehydrogenase, HADH2. In fatty acid metabolism, HADH2 catalyzes the third step of beta-oxidation, the conversion of a hydroxyl to a keto group in the NAD-dependent oxidation of L-3-hydroxyacyl CoA. In addition to alcohol dehydrogenase and HADH2 activites, HSD10 has steroid dehydrogenase activity. Although the mechanism is unclear, HSD10 is implicated in the formation of amyloid beta-petide in the brain (which is linked to the development of Alzheimer's disease). Although HSD10 is normally concentrated in the mitochondria, in the presence of amyloid beta-peptide it translocates into the plasma membrane, where it's action may generate cytotoxic aldehydes and may lower estrogen levels through its use of 17-beta-estradiol as a substrate. HSD10 is a member of the SRD family, but differs from other SDRs by the presence of two insertions of unknown function. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	7.46699e-133
NZ_CP006850.1\|WP_051494647.1\|1918550_1920134_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.94711e-71
NZ_CP006850.1\|WP_025348008.1\|1910587_1911379_+\|thioesterase-family-protein	gnl\|CDD\|379298	pfam13622, 4HBT_3, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	1.67563e-37
NZ_CP006850.1\|WP_148306767.1\|1911607_1912234_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	1.13637e-10
NZ_CP006850.1\|WP_025348007.1\|1907751_1910550_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380492	cd06268, PBP1_ABC_transporter_LIVBP-like, periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.	2.61721e-07
NZ_CP006850.1\|WP_025348010.1\|1912230_1913895_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.96018e-64
NZ_CP006850.1\|WP_081769167.1\|1916663_1918055_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	7.44689e-56
NZ_CP006850.1\|WP_158436171.1\|1920193_1923190_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	1.5986e-67
NZ_CP006850.1\|WP_081769169.1\|1924693_1925578_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.91525e-10
NZ_CP006850.1\|WP_025348025.1\|1930795_1931188_-\|VOC-family-protein	gnl\|CDD\|319901	cd07235, MRD, Mitomycin C resistance protein (MRD). Mitomycin C (MC) is a naturally occurring antibiotic, and antitumor agent used in the treatment of cancer. Its antitumor activity is exerted primarily through monofunctional and bifunctional alkylation of DNA. MRD binds to MC and functions as a component of the MC exporting system. MC is bound to MRD by a stacking interaction between a His and a Trp. MRD adopts a structural fold similar to bleomycin resistance protein, glyoxalase I, and extradiol dioxygenases; and it has binding sites at an identical location to binding sites in these evolutionarily related enzymes.	2.64281e-40
NZ_CP006850.1\|WP_025348026.1\|1931406_1932411_+\|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein	gnl\|CDD\|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	5.64217e-19
NZ_CP006850.1\|WP_025348011.1\|1915084_1915825_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	2.09459e-44
NZ_CP006850.1\|WP_025348017.1\|1924490_1924688_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	4.72502e-17

>NZ_CP006850.1|WP_158436171.1|1920193_1923190_+|CRISPR-associated-helicase-Cas3'
MADVRIDQFAGGYPWAKTDTEGISRAAGGPAWDPLVAHMLDVAAVVFELWDRYLSLSVRNRLAESFGDGNDEHARVMVAFLVALHDLGKASDCFLDQFGTGRAKRNGLDRERAVWEKMARAADLPLAEDMSRVHWARHEHITAAHLARILGCECFECGGTGTEYEDLHVVAMLLAGHHGHIPDKHTVDVAYGAAAPAVWGATHSELAALIADTLGVDLSQVKEKIRFARSASLTLFAGFVVLADWVASSQTWFHYRESASSIESCWEKSQSEAAAAVTALRLARWQPPALTWSDLWPGTEPRGFQQAVIDLLPNRGPALAIIESDTGSGKTRAALWCAYHLARTCGYTGLYMAMPTRAATNQIAVELRAFIAATLNDADSVNFAVVHGTAQATDIVHDLLDAARADGQELDDLSSSIEPGLIGDADPAGLGRVVLDPWYLRRCLGLVSPFGIGTVDQLVLAVQRSSHWFLRMLGLACKTVIIDEAHAYELYQQQLLESAVAWLADAGASVVVLSATLPTSVREALTNAWCRGHRTEVEDAGQSGPITMVDAAGRVRRGGPVETPPELHTVVTLDEDPGIAQLAARLVERVEHGGVAAVIRTRVSSAVDLHAAVVEQAKERGWPAEKNLPPKDIILLHGRMMPRDRLPIEQRLVKLTGLGTDRGQRNPQRPQRLIVIATQVIEQSLDVDFDWIVTDLAPIDLLIQRRGRLHRHQINDSLRAPQFATSRMSVLVRVHNQLPIVEPPDENNRRPGTLDALVYAPYTLAATWEALQSRRGHCSCERCAIDNSDAIHLVTPNDSATLIESVYGAEPRAAGELGQLLDRTWNQWKMALNTEQAEASARAVNPYKCNMTPIGVAELASGAGHGDGEEGGAAGIRSRSRLGDESFTAVLLYRQNDGTLTYDNAGSLLADLKSHNPTRSKRETEARRRQQSDILLNTISIPARWIGPRRIPKPETWRPVTEYGPFAKLHVVELNTDGKCINEPHKVVYSSTRGIEMR
>NZ_CP006850.1|WP_051494647.1|1918550_1920134_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MHVRQVPDSIRVPTPRWDPRTEACIAVLTSDGHATTLGLADVLHQADDLQAIFGTTPGEVVAVVEYLLGICYAAKVHPGTVREWRKWVSGRHSLDTAAQWLLAQPDDAWNIFDPHKPLGQNAMLAPFLDEHGSGPAQLVLEHAGDYNQFFDHHHLEHPTPLSPAEAFRAMLVQHVYGPGLRGRVSGDLLGPKLNNLATGRLATRMRVLALGETVGDTLRLNLQQYESDGPDYFNTTWTQRGRRDFAHKPSGRMPDGPADLHTVLGRSILLRPSRNEDGALCVDRVIVGAGELLVPLPAEFRQDAVLVPRAKGEFSPLRPDVNKALWREAHALYAAVAENKKGTDLYSRLAELSGFRVRLWAVGLAIENNKLLTWLADSFPWVSGREIELYHAARNGSRAAEYVGIALGRAAEIAQRSTYPGAGSDQKGTLSSRFDTRTEHFAAAAAPFHRLLEATADGTTAAEATDEFARTLVDTARRLLANRLRSLPSNSRGLRARAAAENKLHTELTHSKAPISVREAADDDRDQ
>NZ_CP006850.1|WP_025348014.1|1918000_1918567_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTATNDTSDAETPPAEHEQRQPADRLTRWLGGLVRRHDLGALADLRRPKTALTQSHFLAMSYAPSASDDEVYRLVAFLFARYHAGASLPSYGRGNLGTALRKVGSGAVRGPEDPGADRLMARISASRAIPERHLQHAIERMRAGDTAPPSWSMLVDDLSRWTDHGRPAAFEWTRDFYTPNRTKYGAKK
>NZ_CP006850.1|WP_081769167.1|1916663_1918055_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MDPRLLHPQPHQVRSQEVTDPRPQYLSLHLLETVAAALPVRDENGRAKTIVFGGEERNMITSQARRRAERTHSRRRANTNQGPLAGYTMGLRTREWALRISDALVANHQWNKDEALGTARACLEAVGLKFGDKPTTINLTKVLLFAPENTGTVIAADLDAHRVLAAEWFTEYASAKEANSKAADKRRPRRRTAQSEDTDIETQPEPEAGKQDLPRLPKEIRTAILTALAPRDAIDIALYGRFLAEIPDSPNVDGAIQTAHAFTVHAAEQIDDFYAAADDAKLDRKANALDFLDSAEDGGAGMTGYQSLISGTFYRHAALDRRKLRANLRAAGMNEDESDEAALAAEAEFIESFVNAFPDAKRNSTASTGTLPNVVLASDGARPFNYAATFENPVNPAKEGSVALAAAQRLLAHHDLVGRKRPDINPGKVLTYDLDITELLAEYAKAGELPCAEVDTLEELISR
>NZ_CP006850.1|WP_025348012.1|1915821_1916667_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTDATESSVLLIRLAAPLQSWGSLSRFAHRSTDLHPTKSGVIGMLAAALGLDRADPLDTLTELRFGVRADCPGVPVRDYHAVGGGAYPLRPRDLILDHRRATRAAPSTDTGDESEFGDYTLEKWYGAPKYVIRDPESGALITQTQAVSRDAMITTRWYLSDAKFVAAVEHSDNTFLEHLAAALEQPQRLLWLGRKSCPPSGELAGGVHPGTLESVLETTALLPGADPRPWAWIETTPGTPGAAPVADQPLSFLADQRTHATRWETRIRLTPRPDIEWTLIP
>NZ_CP006850.1|WP_025348011.1|1915084_1915825_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MTTSPDNGSAAARFVTTHSILTLDARHPFVLKSLHDAQDMHRTVMSGFLGWVEDGQPEARKLMGVLSTWSLNLRESTLIIVVQANVPADWSRIPSNAMKDKPHTITVDKTIRTGNTYTFRTVVNPTRDRNTPKSIAEPGTRTRKRTPHQTPKWAESWFTDRLQPPGEPPIAPSGTRRIGATTDPNTLTVRMLPTVSSSGAHPGLRIIRAELKGTLTVTDPKTFVEALHTGIGRARAYSAGLLLIRD
>NZ_CP006850.1|WP_025348010.1|1912230_1913895_+|MFS-transporter
MTTTADSPPTPIVLTQKRIWLIFSALIAGMFLASLDQTIVGTAMPTIVGDLGGVSHMAWTATSYLLATTIVMPIYGKFGDMFGRRWLFLFAIAVFTAASVGAAASTSFWEFVVFRGLQGVGGGGLMILAQAIIADVVPAKDRGKYMAPMGAIFGITSVAGPLLGGFFADQLGWQWCFWLNVPIGLAALFIAARYLSIPSHRPKTRPDYLGIVLMSSATTLLILITDWGGKQYAWGSAVMVSMIVALVLVIGAFIAVEANAEEPMLPLWLFRNRTFVLTSAIGLIVGLSMFAALAFIPTYLQMATGASASVSGLLLIPMMVGMMITLIGSMSIITKTGRYRVFPPAGALVIIGGMLWLTRLDAQSSMWLVSAMLFVMGAGLGLIMQIIVLVVQNAVAPDQIGTATSANNYFREMGGAIGVAIFGSIFTNRLTDGLTDVFRTHLPEVMAAHLDPSSLVPSVVKHLPDGLHDAIVGSYVDALVPGFWYLIPAAALAFLLALFIPHMTLSDEAGMIARGEAVMADEGSTGTDAAQRDSAPGRPADQDSAQDPDPQPVR
>NZ_CP006850.1|WP_148306767.1|1911607_1912234_+|TetR-family-transcriptional-regulator
MSPIQHDDAPLGLREQKKRRTRIDLCMAARRLTVERGLDATTVDDIAAAVGVSGRTFFNYYETKLDAVVGPVGEIGTPEARQRFIEGGPSGVLIDDLASLYGSSLEPESKAKEAISLVTEIIHSEPRVLAGFVAAGAKQEAAFVELLDERTGGAVSRDFALLAARLMPALTMSAAVSMTEDPDKSLVTALHEQCALAAQLFTSTEESR
>NZ_CP006850.1|WP_025348008.1|1910587_1911379_+|thioesterase-family-protein
MEAFYHPDPADPSLFHSTELTRGPWSPDAQHAGPPSALLGHVIERCEPRPGFRVGRVAVEILGPVPIEPLRAQARVVRPGRSVELIEATIATERGPVLRANAWRLRVAGPEIEIPVDAIATGAYPGPDTVPAGAEFPSTQPVGFHTGIEYRFVAGSFGAPGPAVCWIRLRYPIVAGTTPSPLERTLAAADSGNGVSAVLDWDRYLFINTDLTVTLHREPAGEWVCLDAVTYPERSGIGMAESRLYDEKGPVGRGTQTLLIGPR
>NZ_CP006850.1|WP_025348007.1|1907751_1910550_+|amino-acid-ABC-transporter-substrate-binding-protein
MADRERYTRKYLNALRAVAVPDERPRILPTLLRRRKNRRLPPPMVRLIAPDTAEFDRATGLLPRSGEWLAEPGGKRAVPRAVVDAAEAPPDMFDPGFSTDGDRELEEHCLPILHELYLCFGSDDTAMGPIAFPRYRTADWLTRQRLTGSATEASEQLRERLPNLLRRAPAADRSASALGAVGGTLARVLTIVLSLWPVVRLWLFVSSHIPGLSRVSYWFMHQRYLTPRLSHSFIGFGVRLTEPMRRRESSDQIAKLLVNAFLEDLRAAYRRTLWRPSGWRRTAFPVALFDQVRPDDSASRLMRLVNEIRNETGLFDPLVIVARIDGSAESPSARFADLGVTVDGEVRDPLKLWRADIDERRRHRGTDSWYLTLPLPDSLSGELPRFGRSELAYPPAPPWAARRSVVAAVALLPVVALVAVAVVVVQPRLAAGCTPWPWRSGVDVTVRGTECVGLSGSAAQVFSDDPELGEMQREVFHQNVVAERLRHDNPRRPLVTLVYFAGMTYIDRNGRYPHAQAEELAGLAVRQRWANRQSGASEPLLRVVIANGGTTMRYATWVVDHQISRLVRSDPTVIGVVGLDRSSDETRRAIARLGELGMPTMATTLSADGLDQVSPTYFQPVLDNSMQAKLVADYVSGARNPDGSTRYGKVYIYVPDDPGDIYVRTLETDLRQALGPDRVGKVDPWTDQGQIPSRPIPCAPADRGQPADLLFFGGRNPDFGPFVNAVAQHCGAAMPPILANDTATRAVSDKLVQDAAPIGFPVHYVAKGVPALLAGSGCVRDGTPDRSANASPSMFTLCTELTELRHRLPHFQVSWPGDRTGIGFDVAELFLGAVKRNRSRPEYSGAAVNRAAIGLELRRKDLDADTVTGDLSFGGEDGQVKGASIAILMTPDLNNADVPPKCLLQLPLPDDGTNGCPPGTDSDTETWVRPPG
>NZ_CP006850.1|WP_025348017.1|1924490_1924688_-|DUF397-domain-containing-protein
MGADLSGAKWFKSTRSVGARECVEVAHLDGGAVGVRDSKNIPGPALVFSGTDWDAFLADIENLSI
>NZ_CP006850.1|WP_081769169.1|1924693_1925578_-|helix-turn-helix-domain-containing-protein
MAGGSTLPRRALGRQLKAFRERKGLSQGASARIMETSPQTYGRLEEGRTTKVTDLALNALADAFGCDNNERRLLLDLAQEIRTASKDKRGWWRSLADAIPMDFNHYLSLEEAAEREFSWQTTIIPGLLHTTDYRREVTWAAHPQSSPEEIERIGDITTRRQDLLTRDGFRFEPYILESVLYGQVGSPAVMGEQLGRLLELSELPNVDIRIVPLKARHPIGLVARSFVYLEFPPLPSSGMGEPPVVYIEGLVGGLYLESDPEVGKYSDVVRQLQAVALSESESRDLISAAESDWR
>NZ_CP006850.1|WP_025348019.1|1925843_1926152_+|hypothetical-protein
MRTRPTAFGWVDYDTSLAPQWDSAQVSRLARRLGYEILWTPTSLIPLVDQVRAADVDAVIAPSTEHIDILTLNNLMSIVNVEIVLPRLSFSKWGALPPRRHG
>NZ_CP006850.1|WP_025348020.1|1926840_1927602_-|3-hydroxyacyl-CoA-dehydrogenase
MKLENAVAVVTGGASGLGLATVKELHSQGAKVVIIDLPSSNGESIAKELGDGVVFAATDVTNEEQVSAALDAAQALGTLRIAVNCAGIGNAIKTVSKKGAFPLADFTKIINVNLIGTFNVIRLAAERIAATELDGEERGVIINTASVAAYDGQIGQAAYSASKGGIVGLTLPVARDLASLNIRVNTIAPGLFHTPLFESLPEEAIKALGAQVPHPARLGNPTEYAALARHIVENPMLNGETIRLDGAIRMAPR
>NZ_CP006850.1|WP_025348021.1|1927794_1928757_-|hypothetical-protein
MKYPSRRTRVLGAAVATAFVIAAFTTGCTAVTAQAHPAASVHNATPAIVAAQRISPDDLAQQMQQAVENAEPGSEVGIDVVDTASGATLAGLDTDQQFYTASVVKLLIALDTMRSAGWQPDSETTATLSTMLSASDDDIADALWDDDGGPQIVSRMAATIGLPDTTPPDDPEQWGETRTTPADVVRIYDYITTDVPSPARDIVLTALGGTTEIAADGTDQYFGIPDGLPGTGWDVKQGWMTLDDSTTIDTTGLVSAGAQSGRYVVVVLTTQPPGIDWTAGGAAVTAAVGALRPALVPNTSAGTVSAETVTCSSICPASGK
>NZ_CP006850.1|WP_081769170.1|1928785_1929448_+|TetR/AcrR-family-transcriptional-regulator
MARGHVGRSLSVRRACWWTRPAVLGHDRTVTKSGYHHGDLRETLLRAAAEQIAAEGVDTVSLRALAQRAGVSHAAPAHHFGNRQGLLTALAIRGFELLADELRAARDDFREMAVAYIGFARRHPGHFDVMFRHDLLRADDPDLIAARVTSGAELRSGVAQLGVADEARPATELAAWSLVHGFASLWREGALTDSDLGGVDPEQLARQMVATVEFVGAKKV
>NZ_CP006850.1|WP_025348023.1|1929464_1929938_-|large-conductance-mechanosensitive-channel-protein-MscL
MLKGFKDFLMRGNVIELAVAVVMGTAFTAIVTSVTKGIVEPLLAVVGTNGQLGLGIQLVADKPATFIAVGPIVSAGINFIMVAAVLYFVLMLPMTTLQKRFSKKKKSEPTQTELLIEIRDLLATQKTSHTNDSHTTDTRAHRDAHPQRHASEMVHEH
>NZ_CP006850.1|WP_038550368.1|1930079_1930814_+|helix-turn-helix-domain-containing-protein
MSDRAPAPYLERPARTCADAVVWRRRVGAGPVTVLPDGCMDLLWLGGRLVVAGPDTRAQHSAAVPETAVHGIRFAPGTAPALLGVVAPELLDQRVELAQLWPARRVRHLADLVAAAPDPAAGLEEIARRCAEAAGPPDPVLAQIVRRLDAGAPVAATADALGLGARRLHRISVSAFGYGPKMLARVLRMRRALDLARSDIGFADAAALAGYADQAHMTRDIRALTGRSPGRVIGSPRAAQPSGA
>NZ_CP006850.1|WP_025348025.1|1930795_1931188_-|VOC-family-protein
MAPELNAIGVVVSDLTAALGFYRRLGLEFGDIMGGGHVEAALPGGFRFMLDSEDNIAADVGSGREWNAASGRIGLAVGCASPAEVDAVFAELVAAGYHGETAPFDAVWGQRYATVHDPDGNSVDLYAPLG
>NZ_CP006850.1|WP_025348026.1|1931406_1932411_+|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein
MATDQTMLHRFVISQMSDAGIDRVRLLRECELPEWTLAGEGVHVPSRIFSRLWELGEKWLDDPDVALHVASRYQLAATRLYDYLFASAPTVGAGLATCGPYVTAVTTNHRFDLVTEGAETTLFLDMIDGEGRGRELVQMWGLVAVLTRTRRVLATSLDPVRVSLRQAAPRRLGAFTEVFGTAVLEFGADADSMTFRTLDMDLPLTTADPVLAEVLQPLAAALPPPPPLISAWPERVAKALADAFSEGEVSLDQVARRLVISPRTLQRRLAESGTTWRRELDRARLARAAAAGPVSRARQAELLGYADAGSMRRAAQRWSMVAHSRPVGPAGCQA

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Crispr_ID: NZ_CP006850_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_9

1926255-1926646

TypeI-E

I-E

Consensus_repeat	Method
GGACCATCCCCGCGTGCGCGGGGAGCAC	CRISPRCasFinder
GGACCATCCCCGCGTGCGCGGGGAGCAC	CRT
GGACCATCCCCGCGTGCGCGGGGAGCAC	PILER-CR

6 spacers

cas3,cas8e,cse2gr11,cas7,cas5,cas6e

The CRISPR arrays of NZ_CP006850_9

>merge|NZ_CP006850|9|1926255-1926646|CRISPRCasFinder,CRT,PILER-CR
AGGCCATCCCCGCATGCGTGGGGAGCACCCGCACACCGACATCGAGGGCCGCTACCTGATCGGACCATCCCCGCGTGCGCGGGGAGCACCGCACAAGTTTTGCCGGTCGCGGATTAGGAACCGGACCATCCCCGCGTGCGCGGGGAGCACGTTTTTAGGATCGACGTCAGGTATCCGGGTGGGGGACCATCCCCGCGTGCGCGGGGAGCACCGAACGAAAGCGATTCCGCGCGCGCACTGTCGGACCATCCCCGCGTGCGCGGGGAGCACGCGTCGTGACTGTCGGCGCTGCGAACCCTACGAGGACCATCCCCGCGTGCGCGGGGAGCACGGCCGGGGTGCGCGCCTGGGTGCCGAGCGTGAAGGACCATCCCCGCGTGCGCGGGGAGCAC

>NZ_CP006850|9|9|1926255-1926646|CRISPRCasFinder
AGGCCATCCCCGCATGCGTGGGGAGCAC	CCGCACACCGACATCGAGGGCCGCTACCTGATC
GGACCATCCCCGCGTGCGCGGGGAGCAC	CGCACAAGTTTTGCCGGTCGCGGATTAGGAACC
GGACCATCCCCGCGTGCGCGGGGAGCAC	GTTTTTAGGATCGACGTCAGGTATCCGGGTGGG
GGACCATCCCCGCGTGCGCGGGGAGCAC	CGAACGAAAGCGATTCCGCGCGCGCACTGTC
GGACCATCCCCGCGTGCGCGGGGAGCAC	GCGTCGTGACTGTCGGCGCTGCGAACCCTACGA
GGACCATCCCCGCGTGCGCGGGGAGCAC	GGCCGGGGTGCGCGCCTGGGTGCCGAGCGTGAA
GGACCATCCCCGCGTGCGCGGGGAGCAC

>NZ_CP006850|9|2|1926255-1926646|CRT
AGGCCATCCCCGCATGCGTGGGGAGCAC	CCGCACACCGACATCGAGGGCCGCTACCTGATC
GGACCATCCCCGCGTGCGCGGGGAGCAC	CGCACAAGTTTTGCCGGTCGCGGATTAGGAACC
GGACCATCCCCGCGTGCGCGGGGAGCAC	GTTTTTAGGATCGACGTCAGGTATCCGGGTGGG
GGACCATCCCCGCGTGCGCGGGGAGCAC	CGAACGAAAGCGATTCCGCGCGCGCACTGTC
GGACCATCCCCGCGTGCGCGGGGAGCAC	GCGTCGTGACTGTCGGCGCTGCGAACCCTACGA
GGACCATCCCCGCGTGCGCGGGGAGCAC	GGCCGGGGTGCGCGCCTGGGTGCCGAGCGTGAA
GGACCATCCCCGCGTGCGCGGGGAGCAC

>NZ_CP006850|9|2|1926316-1926646|PILER-CR
GGACCATCCCCGCGTGCGCGGGGAGCAC	CGCACAAGTTTTGCCGGTCGCGGATTAGGAACC
GGACCATCCCCGCGTGCGCGGGGAGCAC	GTTTTTAGGATCGACGTCAGGTATCCGGGTGGG
GGACCATCCCCGCGTGCGCGGGGAGCAC	CGAACGAAAGCGATTCCGCGCGCGCACTGTC
GGACCATCCCCGCGTGCGCGGGGAGCAC	GCGTCGTGACTGTCGGCGCTGCGAACCCTACGA
GGACCATCCCCGCGTGCGCGGGGAGCAC	GGCCGGGGTGCGCGCCTGGGTGCCGAGCGTGAA
GGACCATCCCCGCGTGCGCGGGGAGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025348029.1\|1934715_1936377_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236236
NZ_CP006850.1\|WP_025348019.1\|1925843_1926152_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025348012.1\|1915821_1916667_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|378243
NZ_CP006850.1\|WP_025348023.1\|1929464_1929938_-\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NZ_CP006850.1\|WP_025348014.1\|1918000_1918567_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NZ_CP006850.1\|WP_025348027.1\|1932502_1932694_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025348017.1\|1924490_1924688_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP006850.1\|WP_025348021.1\|1927794_1928757_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225242
NZ_CP006850.1\|WP_081769170.1\|1928785_1929448_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP006850.1\|WP_051494647.1\|1918550_1920134_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|378189
NZ_CP006850.1\|WP_025348028.1\|1933012_1934716_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341278
NZ_CP006850.1\|WP_038550368.1\|1930079_1930814_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197666
NZ_CP006850.1\|WP_025348010.1\|1912230_1913895_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP006850.1\|WP_081769167.1\|1916663_1918055_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP006850.1\|WP_158436171.1\|1920193_1923190_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP006850.1\|WP_081769169.1\|1924693_1925578_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379262
NZ_CP006850.1\|WP_025348025.1\|1930795_1931188_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319901
NZ_CP006850.1\|WP_025348026.1\|1931406_1932411_+\|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|378890
NZ_CP006850.1\|WP_025348020.1\|1926840_1927602_-\|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|187629
NZ_CP006850.1\|WP_025348011.1\|1915084_1915825_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025348029.1\|1934715_1936377_-\|AMP-binding-protein	gnl\|CDD\|236236	PRK08315, PRK08315, AMP-binding domain protein; Validated.	0
NZ_CP006850.1\|WP_025348012.1\|1915821_1916667_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	2.46828e-31
NZ_CP006850.1\|WP_025348023.1\|1929464_1929938_-\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	3.7908e-41
NZ_CP006850.1\|WP_025348014.1\|1918000_1918567_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	1.10883e-11
NZ_CP006850.1\|WP_025348017.1\|1924490_1924688_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	4.72502e-17
NZ_CP006850.1\|WP_025348021.1\|1927794_1928757_-\|hypothetical-protein	gnl\|CDD\|225242	COG2367, PenP, Beta-lactamase class A [Defense mechanisms].	1.61061e-06
NZ_CP006850.1\|WP_081769170.1\|1928785_1929448_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	1.20377e-09
NZ_CP006850.1\|WP_051494647.1\|1918550_1920134_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.94711e-71
NZ_CP006850.1\|WP_025348028.1\|1933012_1934716_-\|AMP-binding-protein	gnl\|CDD\|341278	cd05974, MACS_like_1, Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS). MACS catalyzes the two-step activation of medium chain fatty acids (containing 4-12 carbons). The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. MACS enzymes are localized to mitochondria.	0
NZ_CP006850.1\|WP_038550368.1\|1930079_1930814_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.35484e-12
NZ_CP006850.1\|WP_025348010.1\|1912230_1913895_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.96018e-64
NZ_CP006850.1\|WP_081769167.1\|1916663_1918055_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	7.44689e-56
NZ_CP006850.1\|WP_158436171.1\|1920193_1923190_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	1.5986e-67
NZ_CP006850.1\|WP_081769169.1\|1924693_1925578_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.91525e-10
NZ_CP006850.1\|WP_025348025.1\|1930795_1931188_-\|VOC-family-protein	gnl\|CDD\|319901	cd07235, MRD, Mitomycin C resistance protein (MRD). Mitomycin C (MC) is a naturally occurring antibiotic, and antitumor agent used in the treatment of cancer. Its antitumor activity is exerted primarily through monofunctional and bifunctional alkylation of DNA. MRD binds to MC and functions as a component of the MC exporting system. MC is bound to MRD by a stacking interaction between a His and a Trp. MRD adopts a structural fold similar to bleomycin resistance protein, glyoxalase I, and extradiol dioxygenases; and it has binding sites at an identical location to binding sites in these evolutionarily related enzymes.	2.64281e-40
NZ_CP006850.1\|WP_025348026.1\|1931406_1932411_+\|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein	gnl\|CDD\|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	5.64217e-19
NZ_CP006850.1\|WP_025348020.1\|1926840_1927602_-\|3-hydroxyacyl-CoA-dehydrogenase	gnl\|CDD\|187629	cd05371, HSD10-like_SDR_c, 17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs. HSD10, also known as amyloid-peptide-binding alcohol dehydrogenase (ABAD), was previously identified as a L-3-hydroxyacyl-CoA dehydrogenase, HADH2. In fatty acid metabolism, HADH2 catalyzes the third step of beta-oxidation, the conversion of a hydroxyl to a keto group in the NAD-dependent oxidation of L-3-hydroxyacyl CoA. In addition to alcohol dehydrogenase and HADH2 activites, HSD10 has steroid dehydrogenase activity. Although the mechanism is unclear, HSD10 is implicated in the formation of amyloid beta-petide in the brain (which is linked to the development of Alzheimer's disease). Although HSD10 is normally concentrated in the mitochondria, in the presence of amyloid beta-peptide it translocates into the plasma membrane, where it's action may generate cytotoxic aldehydes and may lower estrogen levels through its use of 17-beta-estradiol as a substrate. HSD10 is a member of the SRD family, but differs from other SDRs by the presence of two insertions of unknown function. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	7.46699e-133
NZ_CP006850.1\|WP_025348011.1\|1915084_1915825_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	2.09459e-44

>NZ_CP006850.1|WP_025348019.1|1925843_1926152_+|hypothetical-protein
MRTRPTAFGWVDYDTSLAPQWDSAQVSRLARRLGYEILWTPTSLIPLVDQVRAADVDAVIAPSTEHIDILTLNNLMSIVNVEIVLPRLSFSKWGALPPRRHG
>NZ_CP006850.1|WP_081769169.1|1924693_1925578_-|helix-turn-helix-domain-containing-protein
MAGGSTLPRRALGRQLKAFRERKGLSQGASARIMETSPQTYGRLEEGRTTKVTDLALNALADAFGCDNNERRLLLDLAQEIRTASKDKRGWWRSLADAIPMDFNHYLSLEEAAEREFSWQTTIIPGLLHTTDYRREVTWAAHPQSSPEEIERIGDITTRRQDLLTRDGFRFEPYILESVLYGQVGSPAVMGEQLGRLLELSELPNVDIRIVPLKARHPIGLVARSFVYLEFPPLPSSGMGEPPVVYIEGLVGGLYLESDPEVGKYSDVVRQLQAVALSESESRDLISAAESDWR
>NZ_CP006850.1|WP_025348017.1|1924490_1924688_-|DUF397-domain-containing-protein
MGADLSGAKWFKSTRSVGARECVEVAHLDGGAVGVRDSKNIPGPALVFSGTDWDAFLADIENLSI
>NZ_CP006850.1|WP_158436171.1|1920193_1923190_+|CRISPR-associated-helicase-Cas3'
MADVRIDQFAGGYPWAKTDTEGISRAAGGPAWDPLVAHMLDVAAVVFELWDRYLSLSVRNRLAESFGDGNDEHARVMVAFLVALHDLGKASDCFLDQFGTGRAKRNGLDRERAVWEKMARAADLPLAEDMSRVHWARHEHITAAHLARILGCECFECGGTGTEYEDLHVVAMLLAGHHGHIPDKHTVDVAYGAAAPAVWGATHSELAALIADTLGVDLSQVKEKIRFARSASLTLFAGFVVLADWVASSQTWFHYRESASSIESCWEKSQSEAAAAVTALRLARWQPPALTWSDLWPGTEPRGFQQAVIDLLPNRGPALAIIESDTGSGKTRAALWCAYHLARTCGYTGLYMAMPTRAATNQIAVELRAFIAATLNDADSVNFAVVHGTAQATDIVHDLLDAARADGQELDDLSSSIEPGLIGDADPAGLGRVVLDPWYLRRCLGLVSPFGIGTVDQLVLAVQRSSHWFLRMLGLACKTVIIDEAHAYELYQQQLLESAVAWLADAGASVVVLSATLPTSVREALTNAWCRGHRTEVEDAGQSGPITMVDAAGRVRRGGPVETPPELHTVVTLDEDPGIAQLAARLVERVEHGGVAAVIRTRVSSAVDLHAAVVEQAKERGWPAEKNLPPKDIILLHGRMMPRDRLPIEQRLVKLTGLGTDRGQRNPQRPQRLIVIATQVIEQSLDVDFDWIVTDLAPIDLLIQRRGRLHRHQINDSLRAPQFATSRMSVLVRVHNQLPIVEPPDENNRRPGTLDALVYAPYTLAATWEALQSRRGHCSCERCAIDNSDAIHLVTPNDSATLIESVYGAEPRAAGELGQLLDRTWNQWKMALNTEQAEASARAVNPYKCNMTPIGVAELASGAGHGDGEEGGAAGIRSRSRLGDESFTAVLLYRQNDGTLTYDNAGSLLADLKSHNPTRSKRETEARRRQQSDILLNTISIPARWIGPRRIPKPETWRPVTEYGPFAKLHVVELNTDGKCINEPHKVVYSSTRGIEMR
>NZ_CP006850.1|WP_051494647.1|1918550_1920134_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MHVRQVPDSIRVPTPRWDPRTEACIAVLTSDGHATTLGLADVLHQADDLQAIFGTTPGEVVAVVEYLLGICYAAKVHPGTVREWRKWVSGRHSLDTAAQWLLAQPDDAWNIFDPHKPLGQNAMLAPFLDEHGSGPAQLVLEHAGDYNQFFDHHHLEHPTPLSPAEAFRAMLVQHVYGPGLRGRVSGDLLGPKLNNLATGRLATRMRVLALGETVGDTLRLNLQQYESDGPDYFNTTWTQRGRRDFAHKPSGRMPDGPADLHTVLGRSILLRPSRNEDGALCVDRVIVGAGELLVPLPAEFRQDAVLVPRAKGEFSPLRPDVNKALWREAHALYAAVAENKKGTDLYSRLAELSGFRVRLWAVGLAIENNKLLTWLADSFPWVSGREIELYHAARNGSRAAEYVGIALGRAAEIAQRSTYPGAGSDQKGTLSSRFDTRTEHFAAAAAPFHRLLEATADGTTAAEATDEFARTLVDTARRLLANRLRSLPSNSRGLRARAAAENKLHTELTHSKAPISVREAADDDRDQ
>NZ_CP006850.1|WP_025348014.1|1918000_1918567_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTATNDTSDAETPPAEHEQRQPADRLTRWLGGLVRRHDLGALADLRRPKTALTQSHFLAMSYAPSASDDEVYRLVAFLFARYHAGASLPSYGRGNLGTALRKVGSGAVRGPEDPGADRLMARISASRAIPERHLQHAIERMRAGDTAPPSWSMLVDDLSRWTDHGRPAAFEWTRDFYTPNRTKYGAKK
>NZ_CP006850.1|WP_081769167.1|1916663_1918055_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MDPRLLHPQPHQVRSQEVTDPRPQYLSLHLLETVAAALPVRDENGRAKTIVFGGEERNMITSQARRRAERTHSRRRANTNQGPLAGYTMGLRTREWALRISDALVANHQWNKDEALGTARACLEAVGLKFGDKPTTINLTKVLLFAPENTGTVIAADLDAHRVLAAEWFTEYASAKEANSKAADKRRPRRRTAQSEDTDIETQPEPEAGKQDLPRLPKEIRTAILTALAPRDAIDIALYGRFLAEIPDSPNVDGAIQTAHAFTVHAAEQIDDFYAAADDAKLDRKANALDFLDSAEDGGAGMTGYQSLISGTFYRHAALDRRKLRANLRAAGMNEDESDEAALAAEAEFIESFVNAFPDAKRNSTASTGTLPNVVLASDGARPFNYAATFENPVNPAKEGSVALAAAQRLLAHHDLVGRKRPDINPGKVLTYDLDITELLAEYAKAGELPCAEVDTLEELISR
>NZ_CP006850.1|WP_025348012.1|1915821_1916667_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTDATESSVLLIRLAAPLQSWGSLSRFAHRSTDLHPTKSGVIGMLAAALGLDRADPLDTLTELRFGVRADCPGVPVRDYHAVGGGAYPLRPRDLILDHRRATRAAPSTDTGDESEFGDYTLEKWYGAPKYVIRDPESGALITQTQAVSRDAMITTRWYLSDAKFVAAVEHSDNTFLEHLAAALEQPQRLLWLGRKSCPPSGELAGGVHPGTLESVLETTALLPGADPRPWAWIETTPGTPGAAPVADQPLSFLADQRTHATRWETRIRLTPRPDIEWTLIP
>NZ_CP006850.1|WP_025348011.1|1915084_1915825_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MTTSPDNGSAAARFVTTHSILTLDARHPFVLKSLHDAQDMHRTVMSGFLGWVEDGQPEARKLMGVLSTWSLNLRESTLIIVVQANVPADWSRIPSNAMKDKPHTITVDKTIRTGNTYTFRTVVNPTRDRNTPKSIAEPGTRTRKRTPHQTPKWAESWFTDRLQPPGEPPIAPSGTRRIGATTDPNTLTVRMLPTVSSSGAHPGLRIIRAELKGTLTVTDPKTFVEALHTGIGRARAYSAGLLLIRD
>NZ_CP006850.1|WP_025348010.1|1912230_1913895_+|MFS-transporter
MTTTADSPPTPIVLTQKRIWLIFSALIAGMFLASLDQTIVGTAMPTIVGDLGGVSHMAWTATSYLLATTIVMPIYGKFGDMFGRRWLFLFAIAVFTAASVGAAASTSFWEFVVFRGLQGVGGGGLMILAQAIIADVVPAKDRGKYMAPMGAIFGITSVAGPLLGGFFADQLGWQWCFWLNVPIGLAALFIAARYLSIPSHRPKTRPDYLGIVLMSSATTLLILITDWGGKQYAWGSAVMVSMIVALVLVIGAFIAVEANAEEPMLPLWLFRNRTFVLTSAIGLIVGLSMFAALAFIPTYLQMATGASASVSGLLLIPMMVGMMITLIGSMSIITKTGRYRVFPPAGALVIIGGMLWLTRLDAQSSMWLVSAMLFVMGAGLGLIMQIIVLVVQNAVAPDQIGTATSANNYFREMGGAIGVAIFGSIFTNRLTDGLTDVFRTHLPEVMAAHLDPSSLVPSVVKHLPDGLHDAIVGSYVDALVPGFWYLIPAAALAFLLALFIPHMTLSDEAGMIARGEAVMADEGSTGTDAAQRDSAPGRPADQDSAQDPDPQPVR
>NZ_CP006850.1|WP_025348020.1|1926840_1927602_-|3-hydroxyacyl-CoA-dehydrogenase
MKLENAVAVVTGGASGLGLATVKELHSQGAKVVIIDLPSSNGESIAKELGDGVVFAATDVTNEEQVSAALDAAQALGTLRIAVNCAGIGNAIKTVSKKGAFPLADFTKIINVNLIGTFNVIRLAAERIAATELDGEERGVIINTASVAAYDGQIGQAAYSASKGGIVGLTLPVARDLASLNIRVNTIAPGLFHTPLFESLPEEAIKALGAQVPHPARLGNPTEYAALARHIVENPMLNGETIRLDGAIRMAPR
>NZ_CP006850.1|WP_025348021.1|1927794_1928757_-|hypothetical-protein
MKYPSRRTRVLGAAVATAFVIAAFTTGCTAVTAQAHPAASVHNATPAIVAAQRISPDDLAQQMQQAVENAEPGSEVGIDVVDTASGATLAGLDTDQQFYTASVVKLLIALDTMRSAGWQPDSETTATLSTMLSASDDDIADALWDDDGGPQIVSRMAATIGLPDTTPPDDPEQWGETRTTPADVVRIYDYITTDVPSPARDIVLTALGGTTEIAADGTDQYFGIPDGLPGTGWDVKQGWMTLDDSTTIDTTGLVSAGAQSGRYVVVVLTTQPPGIDWTAGGAAVTAAVGALRPALVPNTSAGTVSAETVTCSSICPASGK
>NZ_CP006850.1|WP_081769170.1|1928785_1929448_+|TetR/AcrR-family-transcriptional-regulator
MARGHVGRSLSVRRACWWTRPAVLGHDRTVTKSGYHHGDLRETLLRAAAEQIAAEGVDTVSLRALAQRAGVSHAAPAHHFGNRQGLLTALAIRGFELLADELRAARDDFREMAVAYIGFARRHPGHFDVMFRHDLLRADDPDLIAARVTSGAELRSGVAQLGVADEARPATELAAWSLVHGFASLWREGALTDSDLGGVDPEQLARQMVATVEFVGAKKV
>NZ_CP006850.1|WP_025348023.1|1929464_1929938_-|large-conductance-mechanosensitive-channel-protein-MscL
MLKGFKDFLMRGNVIELAVAVVMGTAFTAIVTSVTKGIVEPLLAVVGTNGQLGLGIQLVADKPATFIAVGPIVSAGINFIMVAAVLYFVLMLPMTTLQKRFSKKKKSEPTQTELLIEIRDLLATQKTSHTNDSHTTDTRAHRDAHPQRHASEMVHEH
>NZ_CP006850.1|WP_038550368.1|1930079_1930814_+|helix-turn-helix-domain-containing-protein
MSDRAPAPYLERPARTCADAVVWRRRVGAGPVTVLPDGCMDLLWLGGRLVVAGPDTRAQHSAAVPETAVHGIRFAPGTAPALLGVVAPELLDQRVELAQLWPARRVRHLADLVAAAPDPAAGLEEIARRCAEAAGPPDPVLAQIVRRLDAGAPVAATADALGLGARRLHRISVSAFGYGPKMLARVLRMRRALDLARSDIGFADAAALAGYADQAHMTRDIRALTGRSPGRVIGSPRAAQPSGA
>NZ_CP006850.1|WP_025348025.1|1930795_1931188_-|VOC-family-protein
MAPELNAIGVVVSDLTAALGFYRRLGLEFGDIMGGGHVEAALPGGFRFMLDSEDNIAADVGSGREWNAASGRIGLAVGCASPAEVDAVFAELVAAGYHGETAPFDAVWGQRYATVHDPDGNSVDLYAPLG
>NZ_CP006850.1|WP_025348026.1|1931406_1932411_+|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein
MATDQTMLHRFVISQMSDAGIDRVRLLRECELPEWTLAGEGVHVPSRIFSRLWELGEKWLDDPDVALHVASRYQLAATRLYDYLFASAPTVGAGLATCGPYVTAVTTNHRFDLVTEGAETTLFLDMIDGEGRGRELVQMWGLVAVLTRTRRVLATSLDPVRVSLRQAAPRRLGAFTEVFGTAVLEFGADADSMTFRTLDMDLPLTTADPVLAEVLQPLAAALPPPPPLISAWPERVAKALADAFSEGEVSLDQVARRLVISPRTLQRRLAESGTTWRRELDRARLARAAAAGPVSRARQAELLGYADAGSMRRAAQRWSMVAHSRPVGPAGCQA
>NZ_CP006850.1|WP_025348027.1|1932502_1932694_-|hypothetical-protein
MLNTFESATQYVIAELEAKGTATREDFDVPAIVATSHAIAESWDFKALDRHTFWSIAASNLRA
>NZ_CP006850.1|WP_025348028.1|1933012_1934716_-|AMP-binding-protein
MTSNTDLYRAARDQLVESATDYDTAVRTFEWPRLTGAFNWAVDWFDVIARGNDRTALWIVEEDGREQRVSFDEMAQRSDRVATWLAGLGVRQGDRVILMLGNQVELWESMLAVAKLGAVVMPTTGALGPGDLIDRITRGAVRFVITNAGDTAKFTEVPGDYDRIVVGGPVEGWHDYAEAAAMESAGPFPTVTDVTDELLVYFTSGTTSKPKMVQHNQISYPVGHLSTMYWIGVRPGDTHLAISAPGWAKHAWSCFFAPWIAEATIFVHNYGRFDAEALLGQLRRAEVNTFCAPPTVWRMLIQADLGERPAGLRETLGAGEPLNPDVIARVEAAWGLTIRDGFGQTETTLQIANTPGQPVKAGSMGRPMPGVPVALIDPVSGEPADEGEICLDLSAHPVNLMTGYLQDPQRNAQVMAGGYYHTGDVAARDEDGYITYIGRTDDVFKSSDYKVSPFELESVLIEHPAVVEAAVVPQPDDTRLSVPKAYVTLAAGWRPDSETARAIFEYARDHLAPYLRVRRIEFTELPKTISGKIRRVELRQREDTAHAAGTVLPGEFRYEDVLTGTAS
>NZ_CP006850.1|WP_025348029.1|1934715_1936377_-|AMP-binding-protein
MGRVRPTSYTHGVWDAPLLGETIGANLDRTVAVHGDRDALVDRVTGVRWSYRQFAAEVDAVALGLLDAGIGKGDRVGIWSPNRAEWTLVQFATAKIGAILVNINPAYRSEELRYVLRQAGIRMLISAREFKTSNYAEIIDRVRPECPELEQVLLFDTAEWEAVVESGRAGDPQRLAAAAARLSPDEPINIQYTSGTTGFPKGATLSHHNILNNGYFVGELCGYTEADRICIPVPFYHCFGMVMGNLAATSHGAAMVIPAAAFEPRATLAAVAEERCTSLYGVPTMFIAELAEPDFDSYDLSGLRTGIMAGSPCPVEVMKQVIERMGMTEVSICYGMTETSPVSTQTRSDDTLVQRTATVGRVGPHLEIKVVDPDTGLTVPRGEPGELCTRGYSVMLGYWNDPERTAEAIDAGRWMHTGDLATMDDDGYVAITGRIKDMVIRGGENIYPREIEEFLYTHPDVLDAQVVGIPDPKYGEELVVWIRMREGASPLDAEAVREFCTGRLAHFKIPRHVHIVDEFPMTVTGKVRKVDIRTTSVRLFGMPEHDQQQTGVQ

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Crispr_ID: NZ_CP006850_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_10

2799578-2799676

Orphan

Consensus_repeat	Method
GCCTCCGCGCCTGATCGCTCATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_10

>merge|NZ_CP006850|10|2799578-2799676|CRISPRCasFinder
GCCTCCGCGCCTGATCGCTCATGCTCTGTCCATCTGCGGCCTGAGCTGGGCGCTGCGTGGTTACGCTTCGCTGCTGCCTCCGCGCCTGATCGCTCATGC

>NZ_CP006850|10|10|2799578-2799676|CRISPRCasFinder
GCCTCCGCGCCTGATCGCTCATGC	TCTGTCCATCTGCGGCCTGAGCTGGGCGCTGCGTGGTTACGCTTCGCTGCT
GCCTCCGCGCCTGATCGCTCATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_051495010.1\|2803431_2804367_+\|RNA-polymerase-sigma-factor-SigJ	unknown	unknown	gnl\|CDD\|132002
NZ_CP006850.1\|WP_038550524.1\|2800428_2801166_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP006850.1\|WP_025348839.1\|2798742_2798964_+\|Trm112-family-protein	unknown	unknown	gnl\|CDD\|225391
NZ_CP006850.1\|WP_025348840.1\|2798970_2799564_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380054
NZ_CP006850.1\|WP_025348833.1\|2788736_2790143_-\|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|237999
NZ_CP006850.1\|WP_025348848.1\|2805454_2807119_-\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|235154
NZ_CP006850.1\|WP_038552891.1\|2807321_2807990_+\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
NZ_CP006850.1\|WP_025348838.1\|2798258_2798732_+\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|377229
NZ_CP006850.1\|WP_025348831.1\|2786516_2787389_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|215135
NZ_CP006850.1\|WP_025348843.1\|2801295_2802030_-\|DsbA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|239322
NZ_CP006850.1\|WP_025348850.1\|2808069_2808468_+\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|379266
NZ_CP006850.1\|WP_025348837.1\|2796072_2798262_+\|membrane-protein	unknown	unknown	gnl\|CDD\|234721
NZ_CP006850.1\|WP_025348851.1\|2808545_2809514_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378976
NZ_CP006850.1\|WP_025348835.1\|2793508_2794645_-\|dTDP-4-amino-4,6-dideoxygalactose-transaminase	unknown	unknown	gnl\|CDD\|183283
NZ_CP006850.1\|WP_081769224.1\|2804450_2804774_+\|DUF3761-domain-containing-protein	unknown	unknown	gnl\|CDD\|315295
NZ_CP006850.1\|WP_025348847.1\|2804823_2805447_+\|DNA-3-methyladenine-glycosylase	unknown	unknown	gnl\|CDD\|234840
NZ_CP006850.1\|WP_025348832.1\|2787441_2788722_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173835
NZ_CP006850.1\|WP_193365185.1\|2794634_2795759_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133030
NZ_CP006850.1\|WP_038550526.1\|2802191_2803385_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP006850.1\|WP_025348834.1\|2790552_2793471_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236121

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_051495010.1\|2803431_2804367_+\|RNA-polymerase-sigma-factor-SigJ	gnl\|CDD\|132002	TIGR02957, putative_sigma_factor, RNA polymerase sigma-70 factor, TIGR02957 family. This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.	3.34164e-110
NZ_CP006850.1\|WP_038550524.1\|2800428_2801166_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.02044e-78
NZ_CP006850.1\|WP_025348839.1\|2798742_2798964_+\|Trm112-family-protein	gnl\|CDD\|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	3.33613e-21
NZ_CP006850.1\|WP_025348840.1\|2798970_2799564_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|380054	pfam17920, TetR_C_16, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. This entry represents the C-terminal domain found in a number of different TetR transcription regulator proteins found in Actinobacteria. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain.	9.05283e-24
NZ_CP006850.1\|WP_025348833.1\|2788736_2790143_-\|cyclic-nucleotide-binding-domain-containing-protein	gnl\|CDD\|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	6.47813e-18
NZ_CP006850.1\|WP_025348848.1\|2805454_2807119_-\|2-isopropylmalate-synthase	gnl\|CDD\|235154	PRK03739, PRK03739, 2-isopropylmalate synthase; Validated.	0
NZ_CP006850.1\|WP_038552891.1\|2807321_2807990_+\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	1.34501e-43
NZ_CP006850.1\|WP_025348838.1\|2798258_2798732_+\|GtrA-family-protein	gnl\|CDD\|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	7.73499e-20
NZ_CP006850.1\|WP_025348831.1\|2786516_2787389_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|215135	PLN02244, PLN02244, tocopherol O-methyltransferase.	4.9032e-17
NZ_CP006850.1\|WP_025348843.1\|2801295_2802030_-\|DsbA-family-oxidoreductase	gnl\|CDD\|239322	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins.	6.5828e-83
NZ_CP006850.1\|WP_025348850.1\|2808069_2808468_+\|DoxX-family-protein	gnl\|CDD\|379266	pfam13564, DoxX_2, DoxX-like family. This family of uncharacterized proteins are related to DoxX pfam07681.	7.34898e-10
NZ_CP006850.1\|WP_025348837.1\|2796072_2798262_+\|membrane-protein	gnl\|CDD\|234721	PRK00302, lnt, apolipoprotein N-acyltransferase; Reviewed.	0.000909858
NZ_CP006850.1\|WP_025348851.1\|2808545_2809514_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	5.55843e-42
NZ_CP006850.1\|WP_025348835.1\|2793508_2794645_-\|dTDP-4-amino-4,6-dideoxygalactose-transaminase	gnl\|CDD\|183283	PRK11706, PRK11706, TDP-4-oxo-6-deoxy-D-glucose transaminase; Provisional.	0
NZ_CP006850.1\|WP_081769224.1\|2804450_2804774_+\|DUF3761-domain-containing-protein	gnl\|CDD\|315295	pfam12587, DUF3761, Protein of unknown function (DUF3761). This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 157 amino acids in length.	1.32489e-16
NZ_CP006850.1\|WP_025348847.1\|2804823_2805447_+\|DNA-3-methyladenine-glycosylase	gnl\|CDD\|234840	PRK00802, PRK00802, DNA-3-methyladenine glycosylase.	1.2191e-82
NZ_CP006850.1\|WP_025348832.1\|2787441_2788722_-\|hypothetical-protein	gnl\|CDD\|173835	cd00687, Terpene_cyclase_nonplant_C1, Non-plant Terpene Cyclases, Class 1. This CD includes terpenoid cyclases such as pentalenene synthase and aristolochene synthase which, using an all-trans pathway, catalyze the ionization of farnesyl diphosphate, followed by the formation of a macrocyclic intermediate by bond formation between C1 with either C10 (aristolochene synthase) or C11 (pentalenene synthase), resulting in production of tricyclic hydrocarbon pentalenene or bicyclic hydrocarbon aristolochene. As with other enzymes with the 'terpenoid synthase fold', they have two conserved metal binding motifs, proposed to coordinate Mg2+ ion-bridged binding of the diphosphate moiety of FPP to the enzymes. Metal-triggered substrate ionization initiates catalysis, and the alpha-barrel active site serves as a template to channel and stabilize the conformations of reactive carbocation intermediates through a complex cyclization cascade. These enzymes function in the monomeric form and are found in fungi, bacteria and Dictyostelium.	3.49844e-46
NZ_CP006850.1\|WP_193365185.1\|2794634_2795759_-\|glycosyltransferase	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	1.05539e-47
NZ_CP006850.1\|WP_038550526.1\|2802191_2803385_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	3.63371e-64
NZ_CP006850.1\|WP_025348834.1\|2790552_2793471_+\|AMP-binding-protein	gnl\|CDD\|236121	PRK07868, PRK07868, acyl-CoA synthetase; Validated.	0

>NZ_CP006850.1|WP_025348840.1|2798970_2799564_-|TetR-family-transcriptional-regulator
MSERTGRRAGESGTREAILDAARSRFAEVGFDKASIRSIAGAAGVDPALVHHYFGTKQRLFSAALNLPIDPEAIRAPIRAAASEDLGETVVRTVVGAWDSSIGEHAVAAFRGILAGGDAALARSFLLEVALKDVREKVDSPPGTGTTRVVLAVSQMIGLLVARKILRVEPVASMPLDDLAALAGPTIQRYLTGDLPG
>NZ_CP006850.1|WP_025348839.1|2798742_2798964_+|Trm112-family-protein
MAEQTLDPTLLSLLACPQDKGPLSLVRDADGNSVLYNPRLRLAYPIDNGIPVLLVDEAREVSDTEHEAFAAQG
>NZ_CP006850.1|WP_025348838.1|2798258_2798732_+|GtrA-family-protein
MSVGAEEPAAAAPEQPGLLLRVIRRQEIAFAAVGAANTLLGMAATIAWLKVLPESWPPAVAVALAYCLSIVFAFFAHRNLVFRVRGHLLRDFLRFVAVNSGGLVLNMAGVQLAVGILDLPETPATVVVMGLVAIASYFGHRYISFRRAAEPATGSGG
>NZ_CP006850.1|WP_025348837.1|2796072_2798262_+|membrane-protein
MIVGYVAVLLANARHFYTDDTESQYTGLWLMMGRHLRDGHLPLMAPEQWMTGNYTMEEAGLFNPPQLLIDLIAPSIDNLALLATVVKLVFAIIAALGVYRICLVYGSRASWAAVAGIAFPLSGWFLFFDEASWVTSLTGIAWMLHAWASAVRYARGPAGDRSRYGAGAFGCGPIPLFVFLYLAISVEYVFPAVEAVLMLAAVAVGELVVLRAWRPVVRLAVVAGAAGLAGLMTYLPAMLSATVSWRGNSQINNDRFLTVPWSESLNASLPSAMPAFTSWWGYVQPLPVTYIAWFLIPALAFVDWDRARRAWRELISVGLFSIMFLMWAAGPGTVGPLRWPARVLPMVAVGLLILVCVLLGRFGTVRDVRARVIAAAVLVGLLFVRTFSADPHDVGWHLLSVLVVGAVGALAVWLGVRRGTAAAALVAIVAMFPIAYWQVSSVQPTPMGWNLPVHRAEAEAAFPKFDGVTIQLGDRALIQPGERTLEGAYGSLVFGNYAKDVRRDYVNGYTPNGHFWFGDMLCMRWDSSVCPDAFRRLFTPEPSTGRPPVDLMKLDRVVLQRALFPDAGNQPPPPGWKWADYPGHERYIRVLERENGPVSTSGGRISDAQGVQAVSLSESDRSSRARVSSPDGGRVVFARLNWPGYHATLDGRELSIAQVSKSFVAVDIPAGTANATLDVTWEPPGWRIGAAGAVGGLLVLILMQVLYLRTRRRDTASAVPEPEAAEPVS
>NZ_CP006850.1|WP_193365185.1|2794634_2795759_-|glycosyltransferase
MPIPSATAQARALAQPPTPDVHPPVTGEGGDRPHRVHSVSVVVPVYRGEQTIAGLVAELHALTETSISPAGNGFAVSEIVLVHDHGPDRSDVVLERLAAEYERVRVIWLSRNFGQDAATIAGMAAARGEWIVTMDEDGQHDPGFIGAFLDTALEQRADLVYSKPTNTRPHGLLRNITSRGAKVVLATVFAFPDSTRFESYRLIRGDIGRQLAEVASNGVYLDVALTWVVGNAAQAPVVLRAEGREESGYNYRRLFSLFWKMVLCSGTRGLRLVSLLGVTLAAGGAVMAAVVIGEAVFGGGHDPEGWASIIVVLLLVSGAILFSLGLIAEYLGVALHVLVGKPLYLTVDSPTPRPVRTGAVSTTAAIGGSNPGEH
>NZ_CP006850.1|WP_025348835.1|2793508_2794645_-|dTDP-4-amino-4,6-dideoxygalactose-transaminase
MSTDHILFSRPYRAAAELPNVAAVLASDHSHGDGPFTAAATAKLRAITGAPHTLLTTSCTHALEMAGLLLELGPDDEVIVPSFAFTSTATSVAMRGATCVFADIDERGNLDPESVADAVTDRTKAIVVIHYGGVGADMDRLLAVADAHGLAIVEDTAHGLGGRWRGRSLGTIGTVGALSFHDTKNVHCGEGGAILLTDDILMGRAEIIREKGTDRARFLRGAVDKYSWQDIGSSYLPSDLNAAVLDAQLAEFDLIQAGRHRVWDAYAAALPDWAARNDVRLMRVPADREHTAHLYYLRTPTEDRRDALIGYLRAHGISAPFHYVPLHSSPAGLKLGRTTVSCRYTEEFSATLLRLPLWPDLSDAQVARVIETVTSFTV
>NZ_CP006850.1|WP_025348834.1|2790552_2793471_+|AMP-binding-protein
MKFDTRALTGPARRLMATAQNGLEVIRFGGLAHDVESSPYEVTERKRMYRLRHYFPDDPAPGRPVALLVPPLMVNADIYDVNAEGGAVGILHRAGIDCWVLDFGSPATEEGGWQRDLADHILALSSAIDTVNELTGHAVHLMGYSQGGMFAYQTTAFRYGKGVQSIVTFGSPVDIVAGLPFGLPYGLVSEVADFVADHVLNRLPITDSMVRVGFQMLDPVKTAKARIDFLRQLHDREALLPKERQRRFLERDGWVGYSGPAAADLLKQFVAHNRMMSGGFVIRDQPVSLAELKCPILAFVGEVDDIGQPAAVRGIVRAAPNAEVYEASVVAGHFGLVAGSTATNQTWPLVRDWVNWQDGNAALPEQIAPMREHVATDRQTTAATRVVHTAASLAEAGAGIGAALGGLAGNALRGSRELTGEAARALPRLTRLGMIQPHTRISLGRLLAEQQRNAPLRDLFLFDDRVHSHAAVGARIDNVVRGLVSVGVRPATRVGVLMETRPSALAAVAALSRIGAVAVLLAPGSEVGRAVESTGATAIVADPENLRDATATGVRVFVLGGGDARALEIPDGADVVDLEQIDPAAVTLPAWFRPDPGLARELAFILVTGTGDKLDLKFITNHRWAVSAFGTASAADLDRRDTVYCLAPLHHSSGLLVSLGGAVAGGSRIALARSLDPPSFAEEVHRYGVTVVTYTWTMLRDILDADTFAAGHPHPIRLFIGSGMPAGLWRRTTERFAPARVLEFYASIEGDVVLANVHGVKIGCKGRPLPGTARVELISYDPVTEQILTDTRGFARRAADNEVGLLIGRAGDSVDLSRGGLRGVFAAGDAWMPTENLFRRDGDGDYWLMDRRDTVIRTPRGPVYTQPIVDALNDIAAVDMEVAFGHRTPEGTLAVAVVSVRADHRLEPADITEGLRALDPAQRPDLVHVVDEIARSSSFRPSTHAVRARLRDEPPRQTWRYDRATDSYEPMS
>NZ_CP006850.1|WP_025348833.1|2788736_2790143_-|cyclic-nucleotide-binding-domain-containing-protein
MTLELPVQTDNHVRKSLSTTAAHQLAHTTKSEPQMQGISSRWLTRMLPWTQVEGGVYRVNRRLTHTVGNGEVEFVIDGAHAHVIPLELRELPALREVEDEEVLAAMARQFVQRDLEPGSVIAEFGNPMDQLMLIVHGKLGKIGTGEYGESTKLGMLGDGDYFGDAMLTDRDAIWPVTVKTLTPVTLLTLPRTAFDRLVEQAPILGDHLSRLADSPVRPQNKYGEANIEITSGHAGEPLLDGTFVDYDSSPREYELGAAQSVLRVHTRVADLFNDPHNQIEQQLRLTVEALHERREYDLVNSPDFGLLNNCDLKQRIYTESGPPTPDDLDELLSMRRSTKFFLAHPKAIAAFGRECNKLGLYPDPVDIDGRRIPAWRGVPILPCGKIPVSETQTTSILAMRVGEKEQGVVGLHQTGIPDEFEPSLNVRFKGIDDQSIISYLVSCYYSAAVLVPDALGILDNVAVARQSD
>NZ_CP006850.1|WP_025348832.1|2787441_2788722_-|hypothetical-protein
MSVLSRAAAPPSGDDLAGVIAALLGTFDHAPPARMPVPGAPVTVHTMVTGVVPRGLLGPTGLGTSGLRLPHRLPGPPAVSAVPAGPDTSESAPAGGSRSDIPPLYCPPPARDDPGLAAAVDEGILQWATEIGLYEGRLDELAKAGFGRLIMLAHPDCDDADRLLAAAKCAVSEWSVDDYYCEEDADDHAPDGTESSAEAELGPRLELAMATMDPVELPARYQIQLDRALGADPILRAFRTSFEHLAHYADPTQLARLRTEIGGWFIALGAEAGWRAAGRMPPVWEYLANRQPHSFLPCMAPIDAVGGYRLDADGYCDPRMRRAVTTAALAAQMVNDLYSMAREDLSGGREFNLPTVLAAEEGCSRREAVQRTAAVHDELVHRFEAEAAAWVATASPPQRRFLEGLWAWMGGNRAWHADSRRYHDHT
>NZ_CP006850.1|WP_025348831.1|2786516_2787389_-|methyltransferase-domain-containing-protein
MTVLQPETDGVLHTNYQRSVAAYWNDNPNDDRVNTELGAVDGLYHHHYGIGEPDWSVLEGPEETRQERIVAELHRLETAQADFLLDHLGDVGPGDRLLDAGSGRGGTSFMANARFGCRVDGVSISEYQVGFANDQAAERGVSDQVEFHYRNMLDTGFDSGSMRGIWTNETDMYVDLPDLFAEFSRLLEPGGRYVCVTGCSNDVTGGRAAAVSWIDAHYGCMIHPRGEYFRAMTANGLIPITVTDLTPATIPYWELRTECELATGVEEPFLTSYREGSFQYLLIAADKVGR
>NZ_CP006850.1|WP_038550524.1|2800428_2801166_-|ABC-transporter-ATP-binding-protein
MDRIVAEPDPAITVEHLRVRRGGREVLHDISLTVPSGSITGLLGPSGCGKTTLMRSFVGTQLVEAGSVRVLGEQAGSRGLRARVGYVTQAPSIYDDLTVHDNVSYFAALYGRDTAAVRSAVDQVGLGDHLRHRGNQLSGGQRTRVSLACALVADPELLVLDEPTVGLDPVLRADLWKQFHDLAAQGRTLVVSSHVMDEAEHCDRLLLMRDGHLLAQLTPDQLRADTGETSLENAFLALITMGQPR
>NZ_CP006850.1|WP_025348843.1|2801295_2802030_-|DsbA-family-oxidoreductase
MAVQVEIWTDVNCPFCYLGKRRFEQALAGFDHRDQVRVVHRSFELDPSLPAEHSGPVVEHIAEKYGISPAQAAANERGIAAQAREAGLAYRTEGRDFGSSFDMHRLLHYALAQGRQDELLDALYRANFAEERPLFGDRERLAEVAVAAGFDAVEVGAVLDDPEAYADDVRSDEQTAAQLGARGVPFFVFDRTYGVSGAQPPEVFAQALEKAWADQAPAMQVLGDGDACGPDGCALPTAPDTAAR
>NZ_CP006850.1|WP_038550526.1|2802191_2803385_+|FAD-dependent-oxidoreductase
MTDISRPHEIVVLGGGYTGMLAAVRLARRTRRMAVRITLVNPSDRFTERLRMHQIAAGTELAHHRIPDLLAGTGVIFRCAAATAIDPVACRVACADGAELEYDTLVYALGSVADVESVPGVAQHAWTLDDPRTAHRMSERLAELDATGGTVVVCGNGLTGVEAATEIAESHPGLAVTLIGSGEPGAMMGPRARAHLERALDRLRIVRRSGVRIAKVLPDAVRLDNGVVVPEALTLWTAGVHVPDLAARAGIEIDATGSVVTDATLRSVSHPRIRAVGDAAAIRQPWGRIHGTCQSGMPSAAYVADAIARDLRGKRVRPFRFGYFHQPVSLGRHDAVIQFTHADDTPKRWYLKGRAAVFYKETVSGSPVPTFRLSRRMNVTVTLSRGGRATRGAGRAA
>NZ_CP006850.1|WP_051495010.1|2803431_2804367_+|RNA-polymerase-sigma-factor-SigJ
MDGAPEHAPRSPRSPAGPPQPRADSADAFTTHRRLLFATAYELLGSVADAEDVLQDAWLKWHGVEQDRVRNPRAYLVRTVTNLSLNRLTSARAVRENYVGPWLPEPLLSTPDTADRMETADTVSTAMLVVLETLGPVERAVFVLRDVFGFSPAEIAGFLDRPEPTVRQISHRARNHVHARRPRYDDDPVARRRITEQFLAAANGGDVNALMELLAPDVTLWNDGGGKVTAARRPLHGPDHVARWLLGVLAKPILTGIEIRPAVLNGEWGMVGEIGGFPVGALTFDLLDGRVVNIRFQVNPDKLGGLRGMGE
>NZ_CP006850.1|WP_081769224.1|2804450_2804774_+|DUF3761-domain-containing-protein
MVGASQVQSIANRPGRSTGSRTTLTARLFAVVIGAAAVLTPMATAQAAPPAFIACPAGDYENVDHACVPSPGQNSDGATAQCRDGSYSYSQHRRGTCSHHGGVERWF
>NZ_CP006850.1|WP_025348847.1|2804823_2805447_+|DNA-3-methyladenine-glycosylase
MPAEELAVEPLAAARRVLGATLRSGPVAVRIVEVEAYGGDPAGPWHDPAAHSGRGRTPRNAVMFGPPGVLYVYFSYGMHTCVNVTSGPDGLASAVLLRAGEVIEGHDIARARRPAARTDADLARGPGNFGSALGIALSDYGTPLFDPASPIRLELPSSAVDPVHIAAGPRVGVSLAADRPWRLWLRDSAAVSAYRRSPRAPEAGRSA
>NZ_CP006850.1|WP_025348848.1|2805454_2807119_-|2-isopropylmalate-synthase
MPSHRYHDVYQRVSVPLTDRHWPSNRITSAPLWVPVDLRDGNQALAEPMDPHRKRRMFEMLVRIGYKEIEVGYPSASRADFDFVRLIRDADLAPADVTLVVFTPARADLIARTLESVEGITNDVVIHMYTATAPVWREVVLGRSRDEVAELILAGGREIARLAGDRPNIRFQFSPEVFMLTEPDFVLEVCDAITELWDATARRPVVLNLPATVEVATPNVYADQIEYMHRNLSRRDGVILSVHPHNDRGTGVACAELAVLAGAQRVEGCVFGNGERTGNVDIATLALNLHAQGVNPMIDFSDIDEIRRTVEYCTRMPVPERHPYVGDLVYTAFSGTHQDAIKKGFADHRRRAAAAGVSESEIDWRIPYLPIDPADVGRAYDAVIRVNSQSGKGGIAYLLHSEYGLDLPRRLQIDFARHVQDHTDDSGAEVSAPMLWELLRSVYCDVPENGIRWAAADSGRMTITVPTSGGTVTRTVPASEAGAAVLKILATDGIAIEILEQSDHPMPAGTGHVVCAHLRVGPDTVWAIGFGDTGPAAELAAIAAAVHRPVPVDR
>NZ_CP006850.1|WP_038552891.1|2807321_2807990_+|FadR-family-transcriptional-regulator
MATVQRQPLAAQAAQLLLDRIKAGEWRLGHKLPGETTLAAQLGVGRSTLREAIRELAGQGVLESRQGAGVFVTALDVTEDWDAVLRRADIRTVIEARVAIEAEAAALAAERRTPADLRAMRRALSARALASDSVEHLVDADTAFHRTVIVAAHNEILLQLFDAFVPRVHRAMAEMLRIRPMTDPAADHRAHERLFEAIRARAADTAADASRVHLSTLKAALT
>NZ_CP006850.1|WP_025348850.1|2808069_2808468_+|DoxX-family-protein
MTAVTASAQTAAAPGRIRHRVLWTLQIVLGLFFIVASGLPKLAGQSDAVRIFHEIGWGDWFRYFAGVVEIAGGIGLLVPRLTGLAAAGLTVTMILAAATQAFVLDAPANAIFPLVLAVIFAWIACERRPARR
>NZ_CP006850.1|WP_025348851.1|2808545_2809514_-|AraC-family-transcriptional-regulator
MDALADLLDGPRARGAFVMRSLLAPPWSLRIQDEAPLTVVVVTRGHAVLIPDDADPIRLGQGAVAIIRGPAPYTVADDPSTPPQAIVHPGQTTTTPDGELLCETWDLGVRSWGTDPDGTAALVTGTYEVAGTVSDRLLRALPERAILDGHEIDERLLGMLVDEAGRDIPGQSSVLDRLLDLLTIAALRAWFARAEAPRWYRAYADPVVGQALRLLEHNPAHDWTVAELAATVGSSRAALARRFTELVGDPPIAYLTEWRLARAADLLRGTDATIESIARQVGYGTAFSLSAAFKRRFGTSPGNHRRSASTPPDALPDAGAGG

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Crispr_ID: NZ_CP006850_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_11

3213527-3213820

Orphan

Consensus_repeat	Method
TCGCCGCCGTGCTCACGGGCGGCCTCGGCC	CRISPRCasFinder

4 spacers

The CRISPR arrays of NZ_CP006850_11

>merge|NZ_CP006850|11|3213527-3213820|CRISPRCasFinder
TCACCCCCGTGTTCGCGCGCGGCCCCGGCCAATTCGCCGCCGTGCTCACGGGCGGCCTCGGCCAGCTCGCCACCGTGTTCGCGGGCGGCGGCCGCCCAGTCGCCGCCGTGCTCACGGGCCGCCTCGGCCCATTCCGCACCGTGGACGCGGGCCGCCGCGGCGAGACTGTCGCGGCGGCGCTTGGCCGTGCGGGCCCAGTCGCCGCGATGGTCGAGAGCCGTCCCGGCCAGCTCGGCGCCGCGCTGCCGCGCCGAATCCGCCCAGTCGCCGCCGTGTTCGCGCGCCGCCTCGGCG

>NZ_CP006850|11|11|3213527-3213820|CRISPRCasFinder
TCACCCCCGTGTTCGCGCGCGGCCCCGGCC	AATTCGCCGCCGTGCTCACGGGCGGCCTCGGCCAGC
TCGCCACCGTGTTCGCGGGCGGCGGCCGCC	CAGTCGCCGCCGTGCTCACGGGCCGCCTCGGCCCAT
TCCGCACCGTGGACGCGGGCCGCCGCGGCG	AGACTGTCGCGGCGGCGCTTGGCCGTGCGGGCCCAG
TCGCCGCGATGGTCGAGAGCCGTCCCGGCC	AGCTCGGCGCCGCGCTGCCGCGCCGAATCCGCCCAG
TCGCCGCCGTGTTCGCGCGCCGCCTCGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025349191.1\|3215411_3216788_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP006850.1\|WP_025349197.1\|3220834_3221086_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025349184.1\|3205992_3206553_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP006850.1\|WP_038550568.1\|3214996_3215422_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP006850.1\|WP_158436222.1\|3201208_3202819_+\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|379080
NZ_CP006850.1\|WP_025349188.1\|3211775_3212414_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP006850.1\|WP_025349193.1\|3218308_3218590_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025349192.1\|3216894_3218304_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP006850.1\|WP_025353670.1\|3214501_3214975_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP006850.1\|WP_025349180.1\|3199749_3201174_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|334202
NZ_CP006850.1\|WP_025349182.1\|3202829_3203786_+\|glucosyl-3-phosphoglycerate-synthase	unknown	unknown	gnl\|CDD\|237556
NZ_CP006850.1\|WP_081769695.1\|3221712_3222498_+\|thioesterase-family-protein	unknown	unknown	gnl\|CDD\|379298
NZ_CP006850.1\|WP_025349185.1\|3206641_3207106_+\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|211538
NZ_CP006850.1\|WP_025349187.1\|3209706_3211770_+\|neutral/alkaline-ceramidase	unknown	unknown	gnl\|CDD\|368090
NZ_CP006850.1\|WP_025349196.1\|3219835_3220738_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379262
NZ_CP006850.1\|WP_025349183.1\|3203712_3205797_-\|acyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP006850.1\|WP_025349189.1\|3212552_3213386_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP006850.1\|WP_025349186.1\|3207196_3209596_+\|glycoside-hydrolase-family-3-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|224389
NZ_CP006850.1\|WP_025349195.1\|3219476_3219707_+\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP006850.1\|WP_051495028.1\|3218774_3218978_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025349191.1\|3215411_3216788_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.41251e-70
NZ_CP006850.1\|WP_025349184.1\|3205992_3206553_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.96885e-08
NZ_CP006850.1\|WP_038550568.1\|3214996_3215422_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.22678e-14
NZ_CP006850.1\|WP_158436222.1\|3201208_3202819_+\|glycosyltransferase-family-39-protein	gnl\|CDD\|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	7.94743e-10
NZ_CP006850.1\|WP_025349188.1\|3211775_3212414_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.7833e-12
NZ_CP006850.1\|WP_025349192.1\|3216894_3218304_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_CP006850.1\|WP_025353670.1\|3214501_3214975_-\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.3315e-23
NZ_CP006850.1\|WP_025349180.1\|3199749_3201174_+\|hypothetical-protein	gnl\|CDD\|334202	pfam00668, Condensation, Condensation domain. This domain is found in many multi-domain enzymes which synthesize peptide antibiotics. This domain catalyzes a condensation reaction to form peptide bonds in non- ribosomal peptide biosynthesis. It is usually found to the carboxy side of a phosphopantetheine binding domain (pfam00550). It has been shown that mutations in the HHXXXDG motif abolish activity suggesting this is part of the active site.	5.47821e-20
NZ_CP006850.1\|WP_025349182.1\|3202829_3203786_+\|glucosyl-3-phosphoglycerate-synthase	gnl\|CDD\|237556	PRK13915, PRK13915, putative glucosyl-3-phosphoglycerate synthase; Provisional.	3.20209e-143
NZ_CP006850.1\|WP_025349185.1\|3206641_3207106_+\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl\|CDD\|211538	TIGR00026, Hypothetical_protein_Rv1261c/MT1299/Mb1292c., deazaflavin-dependent oxidoreductase, nitroreductase family. This model represents a family of proteins found in paralogous families in the genera Mycobacterium and Streptomyces. Seven members are in Mycobacterium tuberculosis. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. [Unknown function, Enzymes of unknown specificity].	2.87696e-11
NZ_CP006850.1\|WP_025349187.1\|3209706_3211770_+\|neutral/alkaline-ceramidase	gnl\|CDD\|368090	pfam04734, Ceramidase_alk, Neutral/alkaline non-lysosomal ceramidase, N-terminal. This family represents N-terminal domain of a group of neutral/alkaline ceramidases found in both bacteria and eukaryotes. The EC classification is EC:3.5.1.23. The enzyme hydrolyzes ceramide to generate sphingosine and fatty acid. The enzyme plays a regulatory role in a variety of physiological events in eukaryotes and also functions as an exotoxin in particular bacteria. This N-terminal domain carries two metal-binding sites, the first for Zn2+ residing within the domain, and the second, for Mg2+/Ca2+ lying at the interface between the two domains.	0
NZ_CP006850.1\|WP_025349196.1\|3219835_3220738_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.10308e-09
NZ_CP006850.1\|WP_025349183.1\|3203712_3205797_-\|acyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	5.60375e-62
NZ_CP006850.1\|WP_025349189.1\|3212552_3213386_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	4.59813e-18
NZ_CP006850.1\|WP_025349186.1\|3207196_3209596_+\|glycoside-hydrolase-family-3-C-terminal-domain-containing-protein	gnl\|CDD\|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	5.13512e-55
NZ_CP006850.1\|WP_025349195.1\|3219476_3219707_+\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	8.85758e-20
NZ_CP006850.1\|WP_081769695.1\|3221712_3222498_+\|thioesterase-family-protein	gnl\|CDD\|379298	pfam13622, 4HBT_3, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	2.01287e-15

>NZ_CP006850.1|WP_025349189.1|3212552_3213386_+|alpha/beta-hydrolase
MPVVDVAAGPIHYTDEGEGPPVVLLHGLFMDHTVWDRVMPLLPTGFRYLRPVLPLGAHPDPMRPDADLTLRGLTGIIADFLAALDLRDVTLVHSDWGGGLLMTAYGLDERVARLVVLPCEAFDNFPPGIPGKLAVLAARIPGGLTLVARQLRIGMIRRIPFVFGHMSRRPVPDAMVRGWTEAALRDPDVRRDVRKYGLSLPSAQQLIDDTEALRKFPGPALVLWSSAGKVMPREHGARLAELLPEGRLVEIDDAYVLSMLDRPDAVAAELTTFLTET
>NZ_CP006850.1|WP_025349188.1|3211775_3212414_-|TetR/AcrR-family-transcriptional-regulator
MSDSVSSPTAERIVTATAELMRRQGYGSTTVKQITAAAHAPIGSLYHHFPGGKQQIAASALRTSGAAYIQLLPMLMDPYPDLREAVLCAFTAAAEQIEQSGWMNMCPVGTVAGEIADSEPELRAVTAEVIDDWLDRGGAYFRARGLAPAAADDFTIAVLGALEGAFILSRTLRSTAPLVTAGQAMAAYLDTLPVAETSGAATVSAGEEPGTN
>NZ_CP006850.1|WP_025349187.1|3209706_3211770_+|neutral/alkaline-ceramidase
MTLTRRSMLAGTVTAAAAAAGVAATGTAGAAPLRATGEAGYLVGAGIADVTGAVAGQGMMGYSELDQVASGLLMRTWARAYIVVDRATGDRIAFVSADIACLFQSVHLAVIQRLAQRFGALYTERNVNVNATHNHNSCGGTAREYAYSLAAYGFQNNSHQAEVDGIVAALVAAHDNLAPGTLALGHGELHDASANRSRVAFELNPPEDKSEFPNAIDPKVTVLRLRQGAKDIGAITWFATHGTSLTDANTLISADNKGYASYRWEHDEMGVRHREGGAGFVAAFAQTNAGDMTPNLGLTPWHPSGPTEDNRLNCALIGERQYQAGRAAFDAARPMSGGGVDAALRYLNMADIAIDGSYTPDGKPARTAPAMMGAAAAATSSEDNWKTQLSFLQEGDTNPVVAALGGLNGPVEQWMRDVQAPKLIVAPLGVLPPRPWVPLTVPIQILRIGDLVLASGPAEYTVVSGLRIRRVVAHALSVPLENVLLQGYSNGYSGYVTTPEEYASQQYEGGETLYGRWTLPAYVQEFDRLARAVAARTDLGRGPAPLDWTTGAQPNLLPPVPADTPVAGRAFGDVLTAPKPSYGRGETVAVEFCGAHPNNDFHTGATYFEVERADGDRWITGYDDNDWCTELHWSRPPGQDSASIIAVHWTIPGDADAGRYRIRYHGDRRDGASTTAFTGATTEFQVG
>NZ_CP006850.1|WP_025349186.1|3207196_3209596_+|glycoside-hydrolase-family-3-C-terminal-domain-containing-protein
MDDRIEQLAKQLDLPAKLRLISGAGMFRMAGDPAIGLAEMPVSDGPSGVRGENWDERDPSVSLPSGTALAATWDRDLLTEIGALIAAEAHRKRVHAVLGPTVNLHRSPLGGRHFECFSEDPMLTAEIASAYVRAVQAHGVAACPKHYVANDSETDRFTVDVRVPSRALHELYLYPFERAVAAGAWMVMAAYNSVDGTTMTESPLLDEPLKGAWGFDGVVVSDWTAVRSTDGAARGTDLCMPGPSPLWGQALADAIATGTVPESAIDEKVRRILRFADRVGGFADSASPPVPDISDEQARALVRRAAAAAMVLVHNDGVLPLAPDTSIAVLGPAAADPRYMGGGSATVIPADTVTPVEGLSAVLPVTHTPGIRLTDDLIPVPLDLVTDPATGTPGLCLRYLDGERVLDTQHRTAGRLVLFGDPNAAAANAIELRARLRADVAGTWRIGVAGLGHCVLELDGETVIDTEVTFEGSDPVAALLDPPQRSVERDLAAGETVEVRIRITVGSGPEAMAGLGAILGVGLGIARPQRAPEDEFAAAIETARRAEVAVVVVGTTEQLESEGRDRTTLALPGRQNDLVAAVAAANPRTVVVVNSGAPVEMPWRDDVAAVLLTWFPGQEFGAALADVLTGAAEPGGRLPTTWPKELADVPVRETIPDADGRLSYDEGIHIGYRAWLRAGVQPAYPFGHGLGYTVWELSELLVDGRDIEVTVANIGERDGKQIIQVYLSRDDSEIERPVRWLAAFAAVTAAAGDQRRVRITVPQRAFEHRTEAGWATESGPFTVHVGTSVIALPLTAPIE
>NZ_CP006850.1|WP_025349185.1|3206641_3207106_+|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MTCADTVAGLGARALRTRGLVRAPIAIYRAGLGFLFGSRMLMLEHIGRTSGARRYVVLEVVDRPGPGELVIVSGFGARSQWYRNIAAEPSVRVWVGWRRGVPARAVAMDDAESAAALARYQRAHPAAWKNLRAMIERATGVPVDTLPMVRLRLR
>NZ_CP006850.1|WP_025349184.1|3205992_3206553_+|TetR/AcrR-family-transcriptional-regulator
MVTAAEQGRDTRARLMDAAIAMIDEHGWGAVTTRLVAERAGVRAGLVHYHFRSVDDLLIDAAVRMVRGLVENMAGAASGDPVTALLASIAGFDDAAETRVFGEILLAASRRDRLRAGLADVLTEFRAGLADRLRADSAVPDPEAAAAVLVAALDGLVLHRLIDPNIRALDFGPALRRLAGAGQETP
>NZ_CP006850.1|WP_025349183.1|3203712_3205797_-|acyltransferase
MSTTVSETTTGSVGTAYRRDLDGLRGLAIALVVVFHIWFGRVSGGVDIFLVLSGYFFTGSLLRRAGSGGPVGVGDTLRRTARRLLPALVVVLGAVLVASVTLRPYTQWGDLAGQTLASMFYYQNWRLALTWSDYLAADPSVSPLQHLWSMSVQGQYYLAALLVVAATVWVCRRLGRPDATRPALAAVITLAGICSFLYAAHGSATHQGWNYYDSAARAWELLVGAGLALAATSLRMPRVVRIVLAVAGLAVVVAGGWITNGANQFPGPPALLPVGAAVALILAGAGVAAARQPWPTRMLASGPLVRLGDLAYSLYLWHWPLLIFLLAEGGGTHAGFALGTAVIAISLGLAYLTHRYIEQPLRMRRPQRTSAAEPMFGPRYRRTTAVAVSLTAAVVASAAVTWSAVVQTHPPRAVGVLDPVRYPGAEALAGGASVPQAKMRPTLYEAPAELPSPTVDGCIADWDHREVVTCTYGVPDAPRTLAVVGNSHAEHWMPALQQLAEQHRFRILVHLKMGCPLTLDPNPMYKGEANPDCRDWSHDVIDLLGQEKPDWVFTTGTRPVDAGGDETPQDYLDVWRALSDEGMKVIAVRDTPWLRRNGIRYRAVDCLARHGDRISCGMRREDALAPVDPALDPSAAFPNVFPIDLTDAVCERDVCPVEVGNILVYHDEHHFTASYARSLAPALGRQLQPLTGWW
>NZ_CP006850.1|WP_025349182.1|3202829_3203786_+|glucosyl-3-phosphoglycerate-synthase
MSYAAPAAEPCCPELIRAKGDRTVSVVVPALNERDTIAGVIASIRHLVGGLVDELVVVDSGSTDDTVARAIAAGAGAVHTREQAVPGVPVRPGKGEVLWRSLAVTTGDIVVFIDSDLHDPDPGFVPALLAPLLRDPGIHLVKGFYRRPLGDDPHGDPDDGGRVTQLVARPLLTALVPDLADVRQPLGGEYAATRTLLADIPFAPGYGVEIGILLDAWRHYGRAGIGEADLGTRVHRNRPTHELAVMSRQIVATLLMRLGIADSGAGLIQFRPEGSGWRRVSTPVSAADRPPMRSLTTSPSAVAAAARVREPASGHSSR
>NZ_CP006850.1|WP_158436222.1|3201208_3202819_+|glycosyltransferase-family-39-protein
MSDGPAAAAREAGLGSAGERTPDAPSDGKRRDRAKPLLLRQVSSIPAGVWIGLIAAVTAVVLIARSGRYRWFGDELYFLAAGHHLAAGYVDQGPLVPLLARLAELVAPESTVALRLPAVAAGIAAIVVSAALAREFGGGPGARILAALGYASCPFLVTQTASLSTFAFDPTAVAVLIWLLMRWMRVRRDRLLLAAGAVAALDLQVKLLLPVVIVALALGIACCGPREVLRRPALWCAAAIAGLPTVPALIWQWRHGWPQLAMGAVIRDEQRAATGGTAGLPMQLVTMGGVLGVVLICCGAWGLVSARLRPYRFLAVTAIVMLLFVIAAGGRPYYLAGLLPVLFAAGACVLAERLPARWWRPVTALTAASSIAIAAGVVVLLPSGAPPHPVATRAELSTRMRISGTTGWDELVTAVARAAATAPDATAVLTRTYWQAAALAHANDARIPPVYSADRGFAAFGRPPPGTATVLCVDTDDAGTRLRRTFSAVEPILRLDNPRGFPGIDAHVTIWRCAGPRASWERIWPEMTTNILDPGI
>NZ_CP006850.1|WP_025349180.1|3199749_3201174_+|hypothetical-protein
MVGFGFFDDWHPRPGRLISWAPTQRSRAAVLAAPEHPIGPSYQQREYLLAAHRQRDSGSRGSRLCMIAFDFPSALDRDAMTRAVTAFVRRHDTFWSWFSHEPGDRIARHVADPADIDLAPADFGEYTDSDAVRDHVQRHARGVFDWDCFGFGVIDRGDSFTVYAAVDHLHTDGVGQALSCVDLLMLYGNELSGGQVPIEPVDGHLAYCERELAANAALTAASEPVRRWLDLLVAHDGAVPSFPMDLGVAADAAGFTEGAVLTVPLFTEAEALRFERVCEEFGGKFLGGLFAAIALTEHELTGRERYFVFTPVNTRAGAGEQGAIGWYTNLVPVAVRVRPGEDFTSLVGRAQSEADGAKDLAEVCVHRVIELAAGDPRIRTRLGFSAPMVSYVDVRRMAGAEMFDRINGGLYGNRASSSEVYLWVNRFPDVTSLSMVFPDTDIAHEAIAKYLSTLTTLCRDIAERDSERTGAAVP
>NZ_CP006850.1|WP_025353670.1|3214501_3214975_-|universal-stress-protein
MTPEWAPGRSSGFELGTDGPRVIMVGIDGSDASWRAAAYAAGLARRQNALLAMIYVQPLMAMAGAYGVDVQGATAEMAEDLAREIREHAEKVEDVYRTRWKFITRRGDPYTVLAEAADELKADGVVVGASEKAGHRLIGSVAVRLVKSGRWPVTVVP
>NZ_CP006850.1|WP_038550568.1|3214996_3215422_-|MarR-family-transcriptional-regulator
MSDEPPSTDPTPDEVWHLLTHVVHDSRGPWKRAVAERMGMPFSRFRVLRRLLPGPLPLKELARSAAMDAPATTVVVNDLEDRGLVARELDPADRRSKRVTVTEAGRAMVAHALATPDPPPPALAALTPAQLRTLRDLLGLL
>NZ_CP006850.1|WP_025349191.1|3215411_3216788_-|MFS-transporter
MPTTIAGLSARHKTIVLVTCCLSLLISSMDATIVNVAIPTIRSDMDAPLSRLQWIVDIYTLTLASLLMLSGATADRFGRKRMFRIGLSVFALGSLLCSLAPTIDLLIGARFVQAIGGSMLNPIAMSIITTVFTGRVERARAIGVWGAVVGISTALGPMVGGVLIDALGWQSVFWINLPICAVALVLTTIFVPESKSATARGIDPVGQALAIVVMFTLVFGLIEHRPAIFAITAVALAGFLYAEARHRSPFIDLRFFRSVPFSAATVTAVCAFAGLGAFLFSASLYLQGVRHYSAVHTGLLYLPMALGMLICSPLSGRLVGRYGTRPSLVSAGILMTVAAALLTTLRPDTPIWQLIVMFAVFGTGFGMVNAPITTAAVSGMPLDRAGAASAVASTSRQVGVSVGVALCGLLTGAGLWWVVAALAACVVVLGIAANTGWALRSRDRIVPLLEHKVPAHVR
>NZ_CP006850.1|WP_025349192.1|3216894_3218304_+|amino-acid-permease
MTTDRKADAPELVSAGEEGYQRGLNPRTIQMIAIGGAIGTGLFYGAGGAIEQAGPALILCYLGAGLAIFVIMRALGELLTYRPVSGSFGEYAHEFLGRFAGFVTGWTYWAVWVATCMAEITVAGKYVKYWFAIPEWVTALVVLGILFAANLISVKLFGEGEFWFSAIKVTAIVAMIAIGIGVLIFGFGHAPDPTVTNLWADGGVFPNGFGQALLALQIVLFAYVGVELVGVTAGEAAEPRRTLRRAINSLPLRIGLFYVGALVVIMSVSSWKVFHAGRSPFVEVFEQIGIPGAAGIINFVLLTAALSSCNSGIYSTGRMVRSLSLRGEAPATLGGLSGRRVPFAGIVLSAAMMVIGVVVNVVSPDKAFNYITSVSTIGIIFVWGMILVCHMIYRVRVRRGELPASDYRLPGAPVTSVVALAFLGLVVVLLFWTDSGRTALIVGLVWAVLVCVGYPLNRMLRRRREPVAG
>NZ_CP006850.1|WP_025349193.1|3218308_3218590_-|hypothetical-protein
MLILAVHDIITAQVGNPTPETPPAADKLLPLVRYFTWFMLLSGTTAIIYAGGRLGWEKWSGGPLESPKMLAGALIGGVTATSAGTLMNTVLGQ
>NZ_CP006850.1|WP_051495028.1|3218774_3218978_-|hypothetical-protein
MLEYSRTRDQHAERHTPATDPAADCADEPRELTHPRARAILHAHDRHLGCRQWVAAAAYLSAGLDDE
>NZ_CP006850.1|WP_025349195.1|3219476_3219707_+|DUF397-domain-containing-protein
MTDSTATTAGLVSDAAWRKSTFSNPSGNCVELADLSNGLVAVRNSRDPEGAVLVYTRPEIDAFLRGAKSGEFDDLA
>NZ_CP006850.1|WP_025349196.1|3219835_3220738_+|helix-turn-helix-domain-containing-protein
MMAEPVRIGRVDSLVAERGPTALRIAVGGQLRKLRESAGITREAAGEHIRGSHAKISRLELGRTGFKDRDVRDLLTLYGVTEEEDRELFLDLVSKANQPGWWHRYNDLLPQWFETYLGLEHASKSIRTFEGQLVPGLLQTEEYTRSVVALGHENAEAARRVELRRKRQEILDRPGAPTLWAVIDEAVLHRPIGGEYVLRAQLDYLVEASVKPNVTIQVLPYAAGGHAAAGSSFTMLRFAEAELPDIVYLEQLTSALYLDRQQDLELYRQVMDRLSVQAATPERSREMMQKAAEQLPECDY
>NZ_CP006850.1|WP_025349197.1|3220834_3221086_-|hypothetical-protein
MNQPTSLGRLGVMDRNRTEHHIYSRETATCFVINAVESTGAATRDDFDIDRIVTTAHAMVNDWDFDTMQPEAFWRIASSCIKQ
>NZ_CP006850.1|WP_081769695.1|3221712_3222498_+|thioesterase-family-protein
MAVSQWSADQVVGPALCGLLARALDNEHATDGFVPVRLTVDLFKPARMHELAVTTTRVRDGRRIRLADAVVVQDGAPAARASVVLLQPSEQPPGEIWTRERQPEPPSPEVAPPSGGPAAPLWHSDESARWTRVPSEHENGSRKRSWQHPANVVDGERPSPFVVAAMAAEQTSMVTNWSSAGVGFINTDLTLALVRMPEGSDIGLEADNHLSRNGIAAGTATLFDRAGVFGTAMITAVANAGRQITASHLDGVIAAASGARN

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Crispr_ID: NZ_CP006850_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_12

6101609-6101705

Orphan

Consensus_repeat	Method
ACGTCGGACACAACCACAACCGCGGCACCGAGACAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_12

>merge|NZ_CP006850|12|6101609-6101705|CRISPRCasFinder
ACGTCGGACACAACCACAACCGCGGCACCGAGACACCGCAGGTCGGACCGCGGCAAACCGAACGTCAGACACAACCACAACCGCGGCACCGAGACAC

>NZ_CP006850|12|12|6101609-6101705|CRISPRCasFinder
ACGTCGGACACAACCACAACCGCGGCACCGAGACAC	CGCAGGTCGGACCGCGGCAAACCGA
ACGTCAGACACAACCACAACCGCGGCACCGAGACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025351731.1\|6093072_6093630_-\|ribosome-recycling-factor	unknown	unknown	gnl\|CDD\|178850
NZ_CP006850.1\|WP_025351732.1\|6093695_6094427_-\|UMP-kinase	unknown	unknown	gnl\|CDD\|234735
NZ_CP006850.1\|WP_148307202.1\|6098296_6099583_+\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NZ_CP006850.1\|WP_025351750.1\|6111822_6112515_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
NZ_CP006850.1\|WP_051495143.1\|6101806_6103003_-\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|223829
NZ_CP006850.1\|WP_025351734.1\|6095896_6096766_-\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NZ_CP006850.1\|WP_025351733.1\|6094946_6095771_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NZ_CP006850.1\|WP_051495141.1\|6092085_6092973_-\|phosphatidate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|366491
NZ_CP006850.1\|WP_025351740.1\|6100353_6101277_-\|tyrosine-recombinase-XerC	unknown	unknown	gnl\|CDD\|234698
NZ_CP006850.1\|WP_025351735.1\|6097035_6097404_-\|DUF202-domain-containing-protein	unknown	unknown	gnl\|CDD\|376882
NZ_CP006850.1\|WP_081769479.1\|6106504_6107356_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP006850.1\|WP_025351739.1\|6099699_6100215_+\|DUF1990-domain-containing-protein	unknown	unknown	gnl\|CDD\|378157
NZ_CP006850.1\|WP_025351745.1\|6105670_6106357_-\|ribonuclease-HII	unknown	unknown	gnl\|CDD\|234574
NZ_CP006850.1\|WP_025351748.1\|6107999_6108926_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025351744.1\|6105250_6105556_-\|DUF2469-domain-containing-protein	unknown	unknown	gnl\|CDD\|313765
NZ_CP006850.1\|WP_025351742.1\|6103277_6104786_-\|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl\|CDD\|223679
NZ_CP006850.1\|WP_025351743.1\|6104785_6105142_-\|YraN-family-protein	unknown	unknown	gnl\|CDD\|237119
NZ_CP006850.1\|WP_081769783.1\|6097400_6097832_-\|DUF202-domain-containing-protein	unknown	unknown	gnl\|CDD\|225060
NZ_CP006850.1\|WP_081769785.1\|6109063_6111565_-\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NZ_CP006850.1\|WP_025351747.1\|6107482_6107824_-\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025351731.1\|6093072_6093630_-\|ribosome-recycling-factor	gnl\|CDD\|178850	PRK00083, frr, ribosome recycling factor; Reviewed.	1.74437e-102
NZ_CP006850.1\|WP_025351732.1\|6093695_6094427_-\|UMP-kinase	gnl\|CDD\|234735	PRK00358, pyrH, uridylate kinase; Provisional.	4.16964e-133
NZ_CP006850.1\|WP_148307202.1\|6098296_6099583_+\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.3361e-16
NZ_CP006850.1\|WP_025351750.1\|6111822_6112515_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.40971e-140
NZ_CP006850.1\|WP_051495143.1\|6101806_6103003_-\|DNA-protecting-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	3.15398e-93
NZ_CP006850.1\|WP_025351734.1\|6095896_6096766_-\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	1.325e-172
NZ_CP006850.1\|WP_025351733.1\|6094946_6095771_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	9.30672e-125
NZ_CP006850.1\|WP_051495141.1\|6092085_6092973_-\|phosphatidate-cytidylyltransferase	gnl\|CDD\|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	7.02979e-54
NZ_CP006850.1\|WP_025351740.1\|6100353_6101277_-\|tyrosine-recombinase-XerC	gnl\|CDD\|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	2.12779e-121
NZ_CP006850.1\|WP_025351735.1\|6097035_6097404_-\|DUF202-domain-containing-protein	gnl\|CDD\|376882	pfam02656, DUF202, Domain of unknown function (DUF202). This family consists of hypothetical proteins some of which are putative membrane proteins. No functional information or experimental verification of function is known. This domain is around 100 amino acids long.	4.99017e-05
NZ_CP006850.1\|WP_081769479.1\|6106504_6107356_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	3.08389e-39
NZ_CP006850.1\|WP_025351739.1\|6099699_6100215_+\|DUF1990-domain-containing-protein	gnl\|CDD\|378157	pfam09348, DUF1990, Domain of unknown function (DUF1990). This family of proteins are functionally uncharacterized.	6.02293e-64
NZ_CP006850.1\|WP_025351745.1\|6105670_6106357_-\|ribonuclease-HII	gnl\|CDD\|234574	PRK00015, rnhB, ribonuclease HII; Validated.	3.22511e-97
NZ_CP006850.1\|WP_025351744.1\|6105250_6105556_-\|DUF2469-domain-containing-protein	gnl\|CDD\|313765	pfam10611, DUF2469, Protein of unknown function (DUF2469). Member proteins often found in Actinomycetes clustered with signal peptidase and/or RNAse-HII.	3.77311e-62
NZ_CP006850.1\|WP_025351742.1\|6103277_6104786_-\|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl\|CDD\|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP006850.1\|WP_025351743.1\|6104785_6105142_-\|YraN-family-protein	gnl\|CDD\|237119	PRK12497, PRK12497, YraN family protein.	1.84304e-52
NZ_CP006850.1\|WP_081769783.1\|6097400_6097832_-\|DUF202-domain-containing-protein	gnl\|CDD\|225060	COG2149, COG2149, Predicted membrane protein [Function unknown].	3.79491e-25
NZ_CP006850.1\|WP_081769785.1\|6109063_6111565_-\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NZ_CP006850.1\|WP_025351747.1\|6107482_6107824_-\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	8.50577e-71

>NZ_CP006850.1|WP_025351740.1|6100353_6101277_-|tyrosine-recombinase-XerC
MEELPGDLRDLLDQYERHLRLGRNRSAHTVRAYLGDARALLNHLCDRSPDASVGEIDLPLLRSWLAELAAGGAARTTMARRASAARTFTAWLTHTGQLVADPGPRLGSARAHRVLPAVLGRDQADAAMTAAESGAAQQDPMALRDRLIVEMLYATGIRVSELCGLDIDDVDRARRLVRVLGKGNKERSVPFGGPADRSLEAWLNFGRPHLATAESGRALLLGRRGRRLDQRQARTVVHDVVSAVPGAPDLGPHGLRHTAATHLLEGGADLRVVQELLGHASMATTQLYTHVSIERLRHVHDQAHPRA
>NZ_CP006850.1|WP_025351739.1|6099699_6100215_+|DUF1990-domain-containing-protein
MTNSPGAQPFTYPDVGATAGDFPAGYHHFQLRRRIGAGRDLFERAGGEILGYRMQRGVGIFQHADTPSAQPGTTLTVRLGFAGVGITAPCRVVYVLDEPDRRGFAYGTLPGHPEVGEELFAVEYDSADDAVYAVVAAFSRPGAWYVRLGGPVVRALQRLIAGRYIDAIRPR
>NZ_CP006850.1|WP_148307202.1|6098296_6099583_+|M23-family-metallopeptidase
MMLLIAAVSWGPAPARATPGSAFDWPLQPRPRVVRGFDRPEHDWLPGHRGVDLAGAAGQSVLAAGAGIVVFAGRVGGKPVVSIDHEGGLRTTYEPVRADVPVGRRVQRGTPLGTLMPGHQGCPEVCLHWGLRRERDYLDPLGLLRRNPVRLKPVPPQSDPVSGRSARGGFLLRQIPLPLPEAFLGPAATPISGNGGRGGRDTALGADVATQIVHHPVGFTVDEHVHATLAPRLGPDRLGQRLTRSAVTAIHPVEPNSGRRREVEFVRGTADFDEHPAHRIGRQGRTGGRDGGQCRFVTREQMPVRIRIRRIRAARTEQFDGVARLGRGGPGPRDSLVTVVDEVDGDLPRRSVDRTHRVGAHGVPVRAGEQQFDVGVGEAVGLEALETGATQVHPDQMVGQSLCAPDLEGQPSTSHDAIPPELGLPNTA
>NZ_CP006850.1|WP_081769783.1|6097400_6097832_-|DUF202-domain-containing-protein
MSSGPESHSDRLDPGKPESRGRDAEPDDGTPGPDDSPELDYRFTLAGERTFLAWIRTALGLLAGGVAVHELVQPFGHHDIRSLLAVCCIVLAVVVAVGAFGRWRLVEAAMRAGRPLPQTVMVPILAGGIAVIAVLAGIGLLLS
>NZ_CP006850.1|WP_025351735.1|6097035_6097404_-|DUF202-domain-containing-protein
MKRSSKPSPSAAPDRDPGLQAERTALAWWRTAIGAMATAVLFLHVATTREQTAILVLALLSTGVLAVVAVTCVLRGRSLRHPGGPGWADGTVAVLTVSAAIAVVGILAAAVSLLPPGQGWHL
>NZ_CP006850.1|WP_025351734.1|6095896_6096766_-|30S-ribosomal-protein-S2
MAVVTMKQLLDSGAHFGHQTRRWNPKMKRFIFTDRNGIYIIDLQQTLTYIDKAYEFVKETVAHGGTVLFVGTKKQAQESIAAEATRVGMPYVNQRWLGGMLTNFSTVHKRLQRLKELEAMEQTGGFEGRTKKEILMLTREKNKLERTLGGIRDMAKVPSAIWVVDTNKEHIAVGEARKLNIPVIAILDTNCDPDLVDYPIPGNDDAIRSAALLTKVVASAVAEGVQARAARASGDAKPEAGAGEPLAEWEQELLAQATPATEGEAAAAPETAAEAELKEDPATKTPADF
>NZ_CP006850.1|WP_025351733.1|6094946_6095771_-|elongation-factor-Ts
MANYTAQDVKRLRELTGSGMMDCKKALEETDGDFDKAVEVLRIKGAKDVGKRAERATAEGLVAAQDGVMFELNSETDFVAKNDEFQNTAGDIAEAAAKVRPADLDALKAVDVNGKTADQVVQELAAKIGEKLELRRVVSFEGPVATYLHKRSSDLPPAVGVLVEYQGEGDAAAEVARAAAMQVAALKAKYVTRDEVPADLVEKERGIAEATAREEGKPEGALPKIVEGRVNGFYKDVVLLEQASVTDSKKTVKQLLDDAGVTITRFARFEVGQA
>NZ_CP006850.1|WP_025351732.1|6093695_6094427_-|UMP-kinase
MDPDTAPDRKGFRRVLLKLGGEMFGGGEVGLDPDVVQTVAEQIAEVVSTGVQVAVVIGGGNFFRGAELEERGMERARSDYMGMLGTVMNSLALQDFLQKQGVDTRVQTAITMGQVAEPYLPLRAKRHLEKGRVVIFGAGMGMPYFSTDTTAAQRALEIGAEVVLMAKAVDGVFTADPKVDSEATMFSEVTHKEVLERGLKVADATAFSLCMDNQMPMLVFNLLTKGNIARAVAGEKIGTLVRS
>NZ_CP006850.1|WP_025351731.1|6093072_6093630_-|ribosome-recycling-factor
MIDEALFDAEEKMEKAVSVAKDDLGSVRTGRANPGMFNRVVAEYYGSPTPITQMASITVPEPRMVVIKPYEQAQLKTIETAIRNSDLGVNPTDDGNVIRVMVPQLTEERRRELVKQAKSKGEDAKVAIRNVRRKTMDELNRIQKDGEAGEDEVGRAEKELDKTTQKYVAQIDELVKHKESELLEV
>NZ_CP006850.1|WP_051495141.1|6092085_6092973_-|phosphatidate-cytidylyltransferase
MPASDPAGETPATDPPSAEPSGKSSRAGRNLPAALAVGIGLGASLIAILLFVPKVLIGVIAVAMAVATWEVAKRLREADVLVPRIPLLVGGQAMIWLAWPWGAQGVVGAFAATALGCMAWRLFDHGLSATPRNFLRDTAITVFVVSWIPLLASFAVLMLQQHDGNLRVLTFMILVVCSDVGGYVAGVLFGRHPMVPAISPKKSWEGFGGSLVFCIIGGLLTVTLLLQANSMIGVLLGIAVVLVATGGDLIESQIKRELGIKDMGTLLPGHGGIMDRLDSMLPSAFVSWLVLTALL
>NZ_CP006850.1|WP_051495143.1|6101806_6103003_-|DNA-protecting-protein-DprA
MIGAPVDLDTTPVPLATGDADDRRLAWAYLSRVVEGPCPALSALIARVGVVEAARAVRECDLPDSLRGPTERRRGIDRAERDLDLMARIGGRLITPDDPEWPQWRLLGLTQLDPVRDADAAVPLALWVRGPLSLQHYTEQSLAVVGARCSTGYGEQATAELAGGLAALGWTIVSGAAFGIDGTAHRAALAAGGSTVAVLACGIDRPYPAQHERLLAEIAETGLVVSEYPPGATAYKHRFLARNRLIAALSEGVLVVEAGSRSGARNTAKWARRLGRPALAVPGPITAAASVGCHRMIRDREAILVTGIEDVHDEVGPLRLSVPEGRESEPELSGDEARVFAELPVAGSRLPRQIADATGLAVAVVRAALAGLEVAGLIGADSSGWFRTARKRGDGMGV
>NZ_CP006850.1|WP_025351742.1|6103277_6104786_-|YifB-family-Mg-chelatase-like-AAA-ATPase
MALGRAHSVAVAGVDGQLVEIEADIGQGLPSVHLVGRPDTTLQESRDRVRAAVANSGEKWPDGRVVLALSPATLPKIGSVYDLALAAAVLHAGDSVPGTRLDGTVLLGELALDGRVRRVRGILPAVLAARTAGRTTVVVPESVLGEAGLVDGIAVLGVPTLRALIDWLRGDGTLSAPDGCYPAPDRVVGDLNEVVGQDEARWALEVAAAGGHHLLLTGPPGIGKTMLAQRLPGLLPPLTESEALEVTAIHSVAGALSDDHPLITTAPFVAPHHSTSVTAMVGGGSGSARPGAVSRAHRGVLFLDECAEIGTKVLEALRTPLEEGEVRIARRDGVARYPARFQLILAANPCPCAPARDVDCICAPLARRRYLGKLSGPLMDRIDIWVQMHAHAAGAFAPADAESSVIVRDRVEAARRAAARRWADYGWTVNGEVPGHVLRQRFRLPSEALAPVETALRQGRMSARGADRAIRVAWTVADLRGAEVPSAQDVLQALNFRQRGAS
>NZ_CP006850.1|WP_025351743.1|6104785_6105142_-|YraN-family-protein
MAHNLALGAHGEELAAQFLREAGIRIVERNWRCRYGELDLIVTDGDTTAFVEVKTRTGLGFGTPAEAVTFAKRQRIRRLALLWLAEQDGPWLRVRFDVISVLLLPGEPPRIEHVRAAF
>NZ_CP006850.1|WP_025351744.1|6105250_6105556_-|DUF2469-domain-containing-protein
MSAEDLEKYETEMELSLYREYKDIVGQFSYVVETERRFYLANSVELRPQNADGEVYFEVRMSDAWVWDMYRPARFVKHVRVITFKDVNIEELEKPDLRLPD
>NZ_CP006850.1|WP_025351745.1|6105670_6106357_-|ribonuclease-HII
MRRAGGLRTLEAALIRSGLGPVAGVDEAGRGCCAGPLVVAACLLAPKAYDSLAGLDDSKKLTEAVREQLYPVIVRRALAWKVVVIPAWEIDAIGIHVANIEGMRRAVAGLETRPGYVLTDGFRVPGISVPSLPVIGGDAAAACIAAASILAKVTRDRMMVELDRELPGYGFAAHKGYNTPEHLSSLAKLGPSDEHRRSWRNVREIGAVERGQDAAATGQVDADAAHAR
>NZ_CP006850.1|WP_081769479.1|6106504_6107356_-|signal-peptidase-I
MRLRDNLFGVADESESVAVPGADDEPKDESASRRRRRGGKKRKQRPFWQELPILIVVAGVIAALVVNFIGRPYVIPSQSMEPTLHGCTGCVGDRIYVEKLSYDFGDPKPGDVVVFKGPSESWNKGYHSQRSSNVVKRGFQNFFSFFGLVPPDENDLVKRVIAVGGQTVQCCDAQGRVMVDGKPLDEPYANYKYPYQPGLPFATKVAGSLIVDPHGREFGPIKVPDGNLWMMGDNRNESLDSRGHVDDEYSGTVPIDDVRGRAVFKIWPPSRIGPVRSQNPQSN
>NZ_CP006850.1|WP_025351747.1|6107482_6107824_-|50S-ribosomal-protein-L19
MNTLDFVDEKSLRTDIPEFRPGDTVNVHVKVIEGNKERIQVFKGAVIRRQGGGIRETFTVRKVSFGVGVERTFPVHSPNIDHIDVVTRGDVRRAKLYYLRDLRGKAAKIKEKR
>NZ_CP006850.1|WP_025351748.1|6107999_6108926_-|hypothetical-protein
MRRWFDDSILAEGRLPLLCFLLGFIVGFLLIRLSVRMIRKEVRWWPGNLRAGNVHIHHMVFGVVLVLASGLGLVATYRSGVGTISALASAFGLGAALVLDEFALIYYLRDVYWEEQGRTSVDAVFVAVAVTGLLLLGFHPLWLLDVNDIRHDSSAAGRSFLGIFALVNLVLAAIVIAKGKIWTGLFGMFFLPLLFVGALRLSRPGAPWARWRYGDRRRLMYRAIVRERRYRRPVIRAKIFVQDLVAGKPDPEHVRTAAEAELARTVVPAPPPPHTWSKAQRAAGTHRTGPPPADTSRIPARRSQRPGS
>NZ_CP006850.1|WP_081769785.1|6109063_6111565_-|RNA-binding-transcriptional-accessory-protein
MSGSLHLARGRSATVVSASVTTASESVSTEAPVRAAGTGTVRLASVGRRIADELAVREEQVRSAVELLDGGSTVPFIARYRKEVTGGLDDAQLRQLEERLHYLRELDDRRGSILESIRGQGKLDAALEAQIMLAETKARLEDIYLPYKPKRRTKAQIAREAGHEPVADALLGDPDTDPAGYTAEQLDGARAILVERFAEDADLVGELRELMWERGQVSSRVRTGKEESGAKFADYFEFSEPFTKLPSHRILALLRGEKEDVLSLSLDTDTEEQEPGTRTVYEGRIAHKFDIADRGRAADTWLLDTVRWAWRTKLQVSLGIDIRMRLRQSAEKDAVDVFAANLRDLLLAAPAGTRTTMGLDPGFRTGVKVAVVDGTGKVVATDTIYPHKPQGQTEKSLAVLGALVARFGVDLIAIGNGTASRETDALATELISRIAASDSARKPTKVVVSEAGASVYSASAYASQELPDLDVSLRGAVSIARRLQDPLAELVKIEPKSIGVGQYQHDVSETLLARSLGAVVEDAVNAVGVDVNTASVPLLSRVSGIATSVAESIVTHRDQNGPFRNRSALLQVPRLGPKAFEQCAGFLRIRGGEDPLDTSAVHPEAYPVVRRILEATGRDMPGLIGNSTALRALRPQDFTDDTFGVPTVSDIISELEKPGRDPRPEFKTAEFAAGVEKVADLEPGMVLEGVVTNVAAFGAFVDVGVHQDGLVHVSAMSHSFVRDPREIVKSGDVVKVKVLEVDVARQRIGLSLRLDDEPGAGKPEKGAGGQRGGQGRGGQPRGQGRGNQSGNQGRGGQERGGQERGQGRNQQRRNAPAPSGSMADALRRAGFGR
>NZ_CP006850.1|WP_025351750.1|6111822_6112515_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MRIDVVTIFPEYLEPLRTALLGKAIDKGIVELDVHNLRRWTHDVHQAVDDSPYGGGPGMVMKPTVWGDALDEVCPDDAVLVVPTPAGVPFTQATAERWSAESHLVFACGRYEGIDQRVFDDAARRVRVEEVSIGDYVLIGGEAAVLVMAEAVVRLIPGVLGNQQSHQQDSFSDGLLEGPSYTRPVSWRGLDVPDILLSGNHARIDAWRRERSLDRTRERRPDLLPPDEPN

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Crispr_ID: NZ_CP006850_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_13

6555587-6555656

Orphan

Consensus_repeat	Method
GTCGACGGGTTCAAGGCCGAGGCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_13

>merge|NZ_CP006850|13|6555587-6555656|CRISPRCasFinder
GTCCAAGGGTTCCGTGCCGAGGCCGAACGGCAGGTCAACGTCACTGTCGACGCAGACGTGGCCGCGGCCG

>NZ_CP006850|13|13|6555587-6555656|CRISPRCasFinder
GTCCAAGGGTTCCGTGCCGAGGCCG	AACGGCAGGTCAACGTCACT
GTCGACGCAGACGTGGCCGCGGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025352193.1\|6552728_6553283_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_148307013.1\|6550002_6550671_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
NZ_CP006850.1\|WP_148307015.1\|6553903_6554566_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352189.1\|6550682_6551504_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371651
NZ_CP006850.1\|WP_025352196.1\|6554651_6554999_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_148307014.1\|6553287_6553743_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352201.1\|6563718_6564246_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_148307016.1\|6566101_6566512_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352202.1\|6564238_6564832_+\|C39-family-peptidase	unknown	unknown	gnl\|CDD\|379241
NZ_CP006850.1\|WP_025352204.1\|6565850_6566087_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_148307018.1\|6567299_6568082_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352199.1\|6561051_6561957_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352200.1\|6561953_6563666_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352191.1\|6552092_6552422_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352197.1\|6555151_6555424_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352190.1\|6551505_6552084_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352203.1\|6564834_6565854_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378098
NZ_CP006850.1\|WP_148307017.1\|6566943_6567276_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352192.1\|6552423_6552732_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352206.1\|6566495_6566951_+\|hypothetical-protein	unknown	unknown	unknown

>NZ_CP006850.1|WP_025352197.1|6555151_6555424_+|hypothetical-protein
MLLNPDLVAERKKAPKAKNPPLLGWTSQMSLLADIADLIYKQLTRDGAARLARPLTAVDFVDLAKRQAAMNRVVAQFSPRHVHLTPQLDP
>NZ_CP006850.1|WP_025352196.1|6554651_6554999_+|hypothetical-protein
MSTTPRARTSAPKEASAPKVGRYYELKEEVAPIPDYVLTEKIRIKEPTREQMQAFWKAPAGEESDRVLLGDAADAVFALYAKLPQRQYNAMTRDIWNHFFPGTGGDEGKSEESSN
>NZ_CP006850.1|WP_148307015.1|6553903_6554566_+|hypothetical-protein
MSDFASEVRQGNPDLELAVLDWAIYLAPKNTAIPAAFTDSAGVILPLPDLYIPVGNLDKKAGAKIATAINSTPVETYGEQGPTRIIRKSRDTTVDFTMQETSAVSLGAFWGQDFTDAKSNPSSGEVNLTISESAFNLEYSLIMIGFDGEVDAEIYTILDSGRATLQKSGDITTNDDGIQMYPVTLQLLKHKTLGYATRISYAGKGWKPLAPAAGFAADAS
>NZ_CP006850.1|WP_148307014.1|6553287_6553743_-|hypothetical-protein
MTSALIAAMSCTVIAACGDSSTPTATTTGAFVLSSGFAFQEDNGSLIRPAELATDANPFSFGCTGIGPFADVAKGAVVSMLDGSDKVIATGKVTETNTSTGPDTRYTCQLSFEIPKAPVGVSGAQVRIGQHSPVALDADYATGHSMLNLVQ
>NZ_CP006850.1|WP_025352193.1|6552728_6553283_+|hypothetical-protein
MSSLRFPDWWRGGFPDRELVVMDALQPVLNVIDVLDDDGNQVYDNGVARRPLACTWLPANYRDVLPVIRVYRGGGAADTGALADPASVQVAAIAATRAASWELMEYCRQWLLSYQSGGTVYRADGTSTLIDSVAEMVGPQQIPELNPDDRMVPLTFRVVCRRPRGLPDYQKVREGLQKLWALAS
>NZ_CP006850.1|WP_025352192.1|6552423_6552732_+|hypothetical-protein
MDDIYIENSFFQLYEKGPECRAVIWLSLELYEAIYREIVAKRTGRLAASTRIWTELENGRWMGVLSANAPYTASHEFGYDDDSEIIAGHHELNRALDIMARV
>NZ_CP006850.1|WP_025352191.1|6552092_6552422_+|hypothetical-protein
MNFSYGETVTVYRPAKGDRTGDPTGSPAPHDIENCAIGWGNTTENHDGRETVLAWVEMYCPPGSDIKNSDRVKVLSNGRTYTVDGDPVTWRSPYTGKQPGMVVRLKGVF
>NZ_CP006850.1|WP_025352190.1|6551505_6552084_+|hypothetical-protein
MDPLATAQDVETQLGRDLTETEQARVEGILAKASDLFRRKARQDFTLGESTVRLKSNGGEIRLEQEPVTAVTTVVDDCGAAVDHRWAGQLLWVTRNGCPLGSHEFVTVTYSHGGEVPDLVRQTIAEVVARVLNVDSRALSGVVTATETTGPFSETLTYAGWAVGGQTMLSPADEAIALSYRYPGGQTIVLRP
>NZ_CP006850.1|WP_025352189.1|6550682_6551504_+|hypothetical-protein
MAITHFIPELWAAQMLDRWTAMTIFANLVNREYEGIAAKGNTVHITGVVAPAVKDYKGNNRTTSADAISDTGIDLLIDQEKNFDFYVDDIDRVQAAGSLDPYTDAAGDGLAQDTDQFLANVLVDHGTALPGTAPSDGDDAFDLVRDARKALNKANAPADGRVLVVNAEFEGLLLGANSKLTAFDTSGDGAGLRQGTVGSLLGFRVVTSNNLPDTDSPQFIAFYPRAAAYVSQIDTVEGMRADNKFADRVRGLHVYGGKVVKPEGVHVFNPAGS
>NZ_CP006850.1|WP_148307013.1|6550002_6550671_+|hypothetical-protein
MTNPANPPAQTETATTAEPVPPTEPAQVTEPVKEPAAPVEPATGEPADPGAAATGTDPLAEIQRLQAEANKWQALSRKNEARAKENADKAQKYTEIEEANKTEVQRLTDRVQKAETELQQARTLALRAEKSASTGVPMALIPSGTEDEMDSAIAAYQGALSAALNSRNAQTPPAAPANLVTAPEGSTKVKQLTRADLQSMSPQEIVQAKNDGRLNELLGKST
>NZ_CP006850.1|WP_025352199.1|6561051_6561957_+|hypothetical-protein
MQLTLIGCTGRRWTISGPGQGMGGVELMPKPKAFYDSPAVTYWIKSGGAKQKYQGYSFKRRDPLFGLVISGDDPEDDLYIADQVRTDLGMYDETFWLEAKTRYGVRRLEMRLLEDPKAFESGDWEGKTPGMMQANTIMVSAACEQPHWAADPVTSDWEVTAGGNATNPEFEHPGNPGDVAIFPRWTLNAPADEWEIPDPSFGQELDFQRQPGEDANLTYKVVQLLAGEDVELNTNPDEPFMLTVSGGFGPWMRSSGRELIYPVKARTEPFETTVSVTGAVAGATATLELDRWYSRPFGATL
>NZ_CP006850.1|WP_025352200.1|6561953_6563666_+|hypothetical-protein
MTTATLPSHADIAAGAQLRRDALNAMRRARPLPRLWTNKKDGSPGLELMGSAEDSITGAFPFKRNQFGTSGTLTIRLDHYLAKWLISIPDDPEAKKNVVITVDHYGGKVRWSGLLKYFKAVKKNGLWYLEVTFIDDLQYLQFLLGAPNPVLPISIFQFPRVLPIFGPAKWAISMMILLNLIRIEGNLWNLPDDPFAVGSWNGLFDWSSWQVLIKAKAIDLDDSSVWTLLATRMNRMDQVIQNALDDAQLTMRYRRILTVDGEVSDVPGVPEVANGALVLEVVDTSGYYSPDGVATGGGIVGGFARTVQGFASGFVEDVQTIAGDVESWPASYYDDGYIGPGDPTRTWIVLRDSKYSNIETSEWTWGPATAARAIAGGDNPLIDNLAHLTIESIGALIGYFCLGGFSGLGSIVADVVMPFLVGTIFAWVEWQNHTRAHNLGWAHLWEVLAQGAENNAWSLGTIVALRGAFLSTASQASHVMEMGSGGRFLPGLMFMPGDRVGSTFEQATATIRVDLCEEIDLSWDYESDRPHEYRAKIGLAQATMSLAERQARQISFALSVIANIGVHLLS
>NZ_CP006850.1|WP_025352201.1|6563718_6564246_+|hypothetical-protein
MDSNGLLRAAPITQENADQTDPRQKHAWALRAMPAPNKQMGDVPLYPSVSGDFSERLEAFGYVHDPTRQTLFVIEGDHPEAGYLNVPKLVDRKEYDEYLAARADTDAAADTWRATAEAALEKLDPKLLNRINAMTDEQKAAERERQKQQLPAAFQRLEEIAGNAQKKTSEETDGD
>NZ_CP006850.1|WP_025352202.1|6564238_6564832_+|C39-family-peptidase
MTEHLLPYDRSIVPQETGWWCGPASTQVVLSGRGIVAAEPDLARLIGTTYDGTSDINLIVPILNRYLGDGLYASRRMPADPPTGDQVTQLWRDITTSIDAGYGMVANIVAPPSNYPRGVKNSVSPAYSGGTVYHYIALMGYDDGPARAVWVADSGFRPFGYWISFDQLASLIPPKGYAAIQHSLWADILTQFIGPRR
>NZ_CP006850.1|WP_025352203.1|6564834_6565854_+|hypothetical-protein
MGSGPIPVRLDTPILFDTGAVVGAVADPAAALDGTKYCGRIFYLRRADWARTGYPDTISRSEADSYKRHGRAIVLNFEDSAANWCLGGYAVGRDRGEVAAQQLAAIGCDTAPVYMSADFRPANSGEMNAVMECLRGFQESSLGPRGRAIYGFAPTMREAKARNLADFYWMCGDGRELFDGDWRSGVRTPDLAHVNLWQQNNEQPYLAGAQVDDNYVLTPTNYGQWQEKPMADEAQQVATQLLGPDGKGWNILGIAAETAPNRNRYLVEAFAVALTQLCGDANFGGWLQLGDGPDADAARADRADAAKRTLVDGIAQVMAQNAQILAQNEQILAALKEQK
>NZ_CP006850.1|WP_025352204.1|6565850_6566087_+|hypothetical-protein
MTASLNPFAYKPAQIAKALVATVTAVIALAGLLANALTTGGLASAGGWVGGVAIVLGPVLVFLQRMEKVAEDIDPGAE
>NZ_CP006850.1|WP_148307016.1|6566101_6566512_+|hypothetical-protein
MEPAVARSFTRLTALLMLVFAGVYGLITIVGGAARWGAPAYEVALQVPGSPQSWGAVLFGASVVGLLGFATGALPVIMVGFALCAGWATCFALCIGVVAARNESVGWGGVVTWAFLALLYAACTAAGGSRFHAPAV
>NZ_CP006850.1|WP_025352206.1|6566495_6566951_+|hypothetical-protein
MRPLFEWLGRALDIESVRHYQVVVYAAVFGAGVQGLVLRETPNAVGQQIGPCFQFFWLGLLVLCPVLTFLGMWVERRHIAGLWLQVAGDAGVSFALLAYTAAIGHATFAGRATFAMWIALALSVCAFALVIRGVRKLRTVSRIVRKLEVDE
>NZ_CP006850.1|WP_148307017.1|6566943_6567276_+|hypothetical-protein
MSEALNLGNLLVGSGVSAVVVALIGAIFQRRMNQANYADALVKTSNEFTKRVDEANEKLSKKVDGLEKKVETLNDNIDELCDLLREAIPTLQASGHDALAERMRAAILRN
>NZ_CP006850.1|WP_148307018.1|6567299_6568082_+|hypothetical-protein
MTVKYGKTPARINSVQLNLSDYFDHTAVLPKIPAEFGHERLVTAWEMLANNQVGDCVWAGAAHETMLWGREAGRDVKFTDECVLADYTAVTGFDPSQADPYTGENPTDQGTDMQAAASYRRRIGIVDTLGNRHQVAAYVALTPGDPDQLAAAAYVFGAVGIGLRVPAYAEDEFSAKKPWDVRHGNATIVGGHYVPVISRRDGNFDVVTWGAIQQMTPMFYRRYCDEAIVYFSREFLTADISPEGFDLAQLQADLKVFARR

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Crispr_ID: NZ_CP006850_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_14

7049155-7049257

Orphan

Consensus_repeat	Method
TGCGACGGGCCTGGAGGAGGCAGCCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_14

>merge|NZ_CP006850|14|7049155-7049257|CRISPRCasFinder
TGCGACGGGCCTGGAGGAGGCAGCCTGCGTAACCCCGCAAGGCCCCGCGGGCGCCGCCATCGGGCACAGCGGCGGCTGCGACGGGCCTGAAGGAGGCAGCCTG

>NZ_CP006850|14|14|7049155-7049257|CRISPRCasFinder
TGCGACGGGCCTGGAGGAGGCAGCCTG	CGTAACCCCGCAAGGCCCCGCGGGCGCCGCCATCGGGCACAGCGGCGGC
TGCGACGGGCCTGAAGGAGGCAGCCTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025352629.1\|7045759_7047139_-\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224787
NZ_CP006850.1\|WP_051495179.1\|7052364_7052952_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352622.1\|7038792_7039839_+\|class-II-fructose-bisphosphatase	unknown	unknown	gnl\|CDD\|236536
NZ_CP006850.1\|WP_025352637.1\|7054877_7056401_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
NZ_CP006850.1\|WP_025352639.1\|7060403_7061819_-\|malate-dehydrogenase-(quinone)	unknown	unknown	gnl\|CDD\|179979
NZ_CP006850.1\|WP_025352621.1\|7038045_7038612_-\|DUF4245-family-protein	unknown	unknown	gnl\|CDD\|379430
NZ_CP006850.1\|WP_158436404.1\|7062979_7063141_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352624.1\|7041442_7042630_-\|FAD-dependent-monooxygenase	unknown	unknown	gnl\|CDD\|169028
NZ_CP006850.1\|WP_038551077.1\|7053052_7053829_-\|isoprenyl-transferase	unknown	unknown	gnl\|CDD\|237825
NZ_CP006850.1\|WP_051495182.1\|7054149_7054773_+\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|273425
NZ_CP006850.1\|WP_081769538.1\|7058606_7059545_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224995
NZ_CP006850.1\|WP_025352628.1\|7044985_7045558_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377971
NZ_CP006850.1\|WP_025352626.1\|7043498_7043942_+\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|226758
NZ_CP006850.1\|WP_025352640.1\|7061909_7062821_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176125
NZ_CP006850.1\|WP_025352630.1\|7047440_7047713_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_193365220.1\|7044017_7044863_-\|acyl-ACP-desaturase	unknown	unknown	gnl\|CDD\|153109
NZ_CP006850.1\|WP_025352623.1\|7039933_7041337_+\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779
NZ_CP006850.1\|WP_025352633.1\|7051428_7052361_+\|type-I-pantothenate-kinase	unknown	unknown	gnl\|CDD\|235466
NZ_CP006850.1\|WP_025352632.1\|7050006_7051203_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352625.1\|7042728_7043442_+\|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|367243

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025352629.1\|7045759_7047139_-\|PhoH-family-protein	gnl\|CDD\|224787	COG1875, COG1875, NYN ribonuclease and ATPase of PhoH family domains [General function prediction only].	0
NZ_CP006850.1\|WP_025352637.1\|7054877_7056401_+\|HAMP-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	1.19059e-39
NZ_CP006850.1\|WP_025352622.1\|7038792_7039839_+\|class-II-fructose-bisphosphatase	gnl\|CDD\|236536	PRK09479, glpX, fructose 1,6-bisphosphatase II; Reviewed.	0
NZ_CP006850.1\|WP_025352639.1\|7060403_7061819_-\|malate-dehydrogenase-(quinone)	gnl\|CDD\|179979	PRK05257, PRK05257, malate:quinone oxidoreductase; Validated.	0
NZ_CP006850.1\|WP_025352621.1\|7038045_7038612_-\|DUF4245-family-protein	gnl\|CDD\|379430	pfam14030, DUF4245, Protein of unknown function (DUF4245). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 188 and 235 amino acids in length.	2.16389e-51
NZ_CP006850.1\|WP_025352624.1\|7041442_7042630_-\|FAD-dependent-monooxygenase	gnl\|CDD\|169028	PRK07588, PRK07588, FAD-binding domain.	1.21846e-76
NZ_CP006850.1\|WP_038551077.1\|7053052_7053829_-\|isoprenyl-transferase	gnl\|CDD\|237825	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional.	5.9308e-129
NZ_CP006850.1\|WP_051495182.1\|7054149_7054773_+\|hemolysin-III-family-protein	gnl\|CDD\|273425	TIGR01065, Hypothetical_UPF0073_protein_yqfA., channel protein, hemolysin III family. This family includes proteins from pathogenic and non-pathogenic bacteria, Homo sapiens and Drosophila. In Bacillus cereus, a pathogen, it has been show to function as a channel-forming cytolysin. The human protein is expressed preferentially in mature macrophages, consistent with a role cytolytic role.	8.55376e-55
NZ_CP006850.1\|WP_081769538.1\|7058606_7059545_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	7.09839e-21
NZ_CP006850.1\|WP_025352628.1\|7044985_7045558_-\|hypothetical-protein	gnl\|CDD\|377971	pfam08310, LGFP, LGFP repeat. This 54 amino acid repeat is found in many hypothetical proteins. Several hypothetical proteins from C.glutamicum and C.efficiens along with PS1 protein contain this repeat region. The N-terminus region of PS1 contains an esterase domain which transfers corynomycolic acid. The C-terminus region consists of 4 tandem LGFP repeats. It is hypothesized that the PS1 proteins in Corynebacterium, when associated with the cell wall, may be anchored via the LGFP tandem repeats that may be important for maintaining cell wall integrity [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16]. Deletion of Corynebacterium glutamicum csp1 protein results in a 10-fold increase in the cell volume of the organism and infers the corresponding proteins involvement in the cell shape formation. The secondary structure of each repeat is predicted to comprise two beta-strands and one alpha-helix [Adindla et al. 2004].	1.33511e-11
NZ_CP006850.1\|WP_025352626.1\|7043498_7043942_+\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|226758	COG4308, LimA, Limonene-1,2-epoxide hydrolase [Secondary metabolites biosynthesis, transport, and catabolism].	2.17138e-23
NZ_CP006850.1\|WP_025352640.1\|7061909_7062821_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176125	cd08434, PBP2_GltC_like, The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold. GltC, a member of the LysR family of bacterial transcriptional factors, activates the expression of gltA gene of glutamate synthase operon and is essential for cell growth in the absence of glutamate. Glutamate synthase is a heterodimeric protein that encoded by gltA and gltB, whose expression is subject to nutritional regulation. GltC also negatively auto-regulates its own expression. This substrate-binding domain has strong homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.82249e-50
NZ_CP006850.1\|WP_193365220.1\|7044017_7044863_-\|acyl-ACP-desaturase	gnl\|CDD\|153109	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain. Acyl-Acyl Carrier Protein Desaturase (Acyl_ACP_Desat) is a mu-oxo-bridged diiron-carboxylate enzyme, which belongs to a broad superfamily of ferritin-like proteins and catalyzes the NADPH and O2-dependent formation of a cis-double bond in acyl-ACPs. Acyl-ACP desaturases are found in higher plants and a few bacterial species (Mycobacterium tuberculosis, M. leprae, M. avium and Streptomyces avermitilis, S. coelicolor). In plants, Acyl-ACP desaturase is a plastid-localized, covalently ACP linked, soluble desaturase that introduces the first double bound into saturated fatty acids, resulting in the corresponding monounsaturated fatty acid. Members of this class of soluble desaturases are specific for a particular substrate chain length and introduce the double bond between specific carbon atoms. For example, delta 9 stearoyl-ACP is specific for stearic acid and introduces a double bond between carbon 9 and 10 to yield oleic acid in the ACP-bound form. The enzymatic reaction requires molecular oxygen, NAD(P)H, NAD(P)H ferredoxin oxido-reductase and ferredoxin. The enzyme is active in the homodimeric form; the monomer consists mainly of alpha-helices with the catalytic diiron center buried within a four-helix bundle. Integral membrane fatty acid desaturases that introduce double bonds into fatty acid chains, acyl-CoA desaturases of animals, yeasts, and fungi, and acyl-lipid desaturases of cyanobacteria and higher plants, are distinct from soluble acyl-ACP desaturases, lack diiron centers, and are not included in this CD.	4.54413e-63
NZ_CP006850.1\|WP_025352623.1\|7039933_7041337_+\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NZ_CP006850.1\|WP_025352633.1\|7051428_7052361_+\|type-I-pantothenate-kinase	gnl\|CDD\|235466	PRK05439, PRK05439, pantothenate kinase; Provisional.	0
NZ_CP006850.1\|WP_025352625.1\|7042728_7043442_+\|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl\|CDD\|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	7.48041e-12

>NZ_CP006850.1|WP_025352630.1|7047440_7047713_+|hypothetical-protein
MSDPAELDKLSSKELHDRAVKHAVRHGDVKFLWRLLEQIPAAAAATGDIGESEADIKYVLPMLDDYVHAGEGKIAEVLRPLYIEYLSDHD
>NZ_CP006850.1|WP_025352629.1|7045759_7047139_-|PhoH-family-protein
MTDARSVIAPSNTRSEQSGGSGKGAGTSPRKSFVIDTSVLLSDPWAMTRFGEHHVVLPLVVISELEAKRHHHELGWFAREALRNLDDLRLRHGRLDQQVPIGTDGGTLQVELNHTDPNVLPVGFRTDTNDSRILACALNLAAEGQRVVLVSKDIPLRVKAGAVGLPAEEYHAQDVVISGWTGMAELEVAADVVDRLYADSIVDLDEARDLPCHTGIRLLGTNGSALARVTADKRVQLVRGDREAFGLHGRSAEQRIALDLLLDESVGIVSLGGKAGTGKSALALTAGLEAVLERRSQRKVVVFRPLYAVGGQELGYLPGSESEKMGPWAQAVFDTLDGLASHEVMEEVLSRGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGSGSRVVLTHDVAQRDNLRVGRHDGVAAVIEKLKGHPLFAHVTLTRSERSPIAALVTEMLEEYGPNS
>NZ_CP006850.1|WP_025352628.1|7044985_7045558_-|hypothetical-protein
MHHFARRSAAAAMALAGAALLFTAACSSDDNDNNSSATTTAGMAETTGAMASGTTTPGEMPSGTAAATETKITTQNGQEIAVAGNILAKYNEMGGAQSPLGEPTGAAVEGPNGGSCQEFTGGAICWSEQTQAHVVWGDIRTAWEGEGGVNGHLGYPTSDEKDNPNGKESDFTGGTITWNSSDRQTQVTPK
>NZ_CP006850.1|WP_193365220.1|7044017_7044863_-|acyl-ACP-desaturase
MTDRELLESLAGAVEDNLRRHDEKVRDWQPHDYVPFDDGRNFAFLGGVDWDPQQVELGEIAALSLTVSVLIADNLPSYHRELGKRLRSGPWWRWVGRWTAEENRHEILIRNYLMVTRAVDPVELERARMTHMTTGFRRPALHLLDVLAQCAFEESASVVRHCNIAALRENSTVTAIAERIAIDDELQAEFFGNLVAAALDLVPDQTMRAIADRIAEFQVPELTLPDGRNSTEVLAEAGIYDPARTGDLVFAPLLQRWNIFSRNDFGSAGNAARAEIEHLRR
>NZ_CP006850.1|WP_025352626.1|7043498_7043942_+|nuclear-transport-factor-2-family-protein
MGELPELQQNAVTTVREFFTAMEIGAVNEALDLLDPDIVWKNTSLPDIRGIQRVGMVLRGLSRDAFGFRADMHHIAAETDGAPAVEGETVLTQRTDYLRMGPLEVAFWVCGTFELVDGRITLWHDHFSWENLLRGTAAGVWNMIRRR
>NZ_CP006850.1|WP_025352625.1|7042728_7043442_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MTGPTALELLWGATQRPRRGPKPSLSLERIVAEAVALADADGLAAVSMQRLAERLGCAKMALYRYVPGKAELTALMLDTALGAPPAPHTAASDPEPWRAALREWATTIDERYRAHPWSIELTPGVRPLGPNELGWMEAALTALAGTGLTGAERLDTVVLLTGHVRSLVQQTRASSPQEAEDELARQVGAVMAEHAERFPEVVAAFADSGPDDSNAALEYGIERILDGVAALIARRAG
>NZ_CP006850.1|WP_025352624.1|7041442_7042630_-|FAD-dependent-monooxygenase
MRNTTVLISGASIAGPALAFWLQRYGFTVTVVERAAQLRPGGQAVDFKGATHRTVLERMGIWDEIQRRQTGKTDMVINDAQGRELADISGDFTGGDVEILRGDLAEILYERTAANCEYLFGDSITALRETAAGVEIEFENAPARTFDLVVGCDGIHSRVRALAFGPEADFVKHQGYYYCTAGAAGWGNDQEGPRRRGRSAAYNEPGRLAVRGGNKAAHMYMFAADRLEYDRRDEASQRRVLAEAFAGVDGPVPAMMSELAELDSFYLDSLGLVRMKGNYTKGRVALVGDSAYGNTLGGFGTGLAVVGAYVLAGELALADGDHAAAFARYNELMKRYAKIAGNTNAGRFLAPRTARGIRMRNWFLGSWAFGLMLKYSDNAANDIDLRDYPALVSAV
>NZ_CP006850.1|WP_025352623.1|7039933_7041337_+|class-II-fumarate-hydratase
MSDETQYRIEHDTMGEVRVPVNALWRAQTQRAVENFPISGRGLERAQIRALGLLKAACAVVNRDLGLLEGGKAEAIIAAANEIAEGRHDDQFPIDVFQTGSGTSSNMNANEVIASLAAARGVTVHPNDDVNMSQSSNDTFPTATHLAATEAVVKELLPALNHLRLRLLDKATEWRTVVKSGRTHLMDAVPVTLGQEFGGYTRQVEAGTERLIAALPRLGELPIGGTAVGTGLNAPAGFGAKVVAELRKTTGLDELSEALDHFEAQAARDGLVEISGSLRTVAISLTKIANDIRWMGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAVAWGGGNGAFELNVYIPVMARNVLESIRLLANVSRLFADKCVSGLVANTEHLRQLAESSPSIVTPLNSAIGYEEAAAVAKQALREKKTIRETVVDRGLIGEKLSEEELDRRLDVLSMAKVDDRD
>NZ_CP006850.1|WP_025352622.1|7038792_7039839_+|class-II-fructose-bisphosphatase
MTAPTPAPNRRREAPDRNLALELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRQLVATVSMKGVVVIGEGEKDEAPMLYNGEAVGDGTGPEVDFAVDPIDGTTLMSKGSSGAISVLAVAERGAMFDPSAVFYMEKIAVGPEAADVIDLSAPIAENLRRVAKAKNSLVSDLTVCVLDRPRHARHIEEVREAGARIRLISDGDVAGAIACARPDSGTDMLVGIGGTPEGIIAAAALRCMGGALQGRLAPKDDAEKQKALDAGHDLDRILNTEDLVSGENVFFSATGVTDGDLLRGVRYYSGGASTQSIVMRSKSGTVRIIDAYHRLTKLHEYASVDFVGDEDAIPPLP
>NZ_CP006850.1|WP_025352621.1|7038045_7038612_-|DUF4245-family-protein
MVSQKPRIMNDYRDLIWSMIPLVLICVVLAAVASQCTFTAHGPTPGQVPKFDVQSALHDDAKVLPFPIRDPEVPSDWQSNSGSRDTITGPSGGTISTVGYITGNGTYIQLSQSNATESAFADHVVKTRSPSGSRTVGDQKWTVYHVEGSETAWISDFGASRVLIKGAAGESAYQALAQAVGTAAPLQS
>NZ_CP006850.1|WP_025352632.1|7050006_7051203_-|hypothetical-protein
MHAHPFVTEYLRLGLAFDRLEPGFVDAYTGDPALRRAVESAPAPQPRELADRAAALHKELPEAGLDEQRTEFLAAHLLALECSGRKFAGDDISFVEEVRAYFDVDIELGDIDDYQDAHRQLDEVLAGDGPLLDRMTAHRKADEIPPERLTECVRAFSGALRERVRERYPLPDHEQVEYEIVGDKPWSGFNYYLGNYRSRVAINSDLKQHMANLPALIAHEAYPGHHTEHCRKEAGLVAAGQDEQTLFVVNTPQCLMAEGLADLALKSIIGPDWGIWAQEIYADLGLRFDGERAQRLSIASAKLLGVRQDAALLLHDRGRDADEVAGFLQRWSLSTPERARQSLRFLSSPLWRAYISTYVEGYRLLGGWLDRAADTGDRVARFGRLLDEPLTPAAVRRM
>NZ_CP006850.1|WP_025352633.1|7051428_7052361_+|type-I-pantothenate-kinase
MARMSEPSPYVEFDRKQWRTLRKSTPLILTEEELTGLRGLGEQIDLEEVAEVYLPLARLIHLQVAARQRLFAATATFLGETHPDQQVPFVIGIAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPTAELTRRGIMHRKGFPESYNRRKLLRFVTEVKSGAAEVCAPMYSHIVYDILPDQYHCVRQPDILIVEGLNVLQTGPRLMVSDLFDFSIYVDARIEDIERWYVNRFLSLRKTAFADPQSHFHHYAKFTDSEATVAAQEIWNATNRPNLVENILPTRPRATLVLRKDSDHSINRIRLRKL
>NZ_CP006850.1|WP_051495179.1|7052364_7052952_-|hypothetical-protein
MRAGPAPASGTLVPYVGYGEFGRRFVAYAASEQRIARVFAELAGSAFDFGPIGVGPAHLARASAKVLLGQPELERSAGEVVGFDLAIPLDIDLLLDLAVDRHRFAITGFVDVHLTVRTAAPLRIIIDIAEPRPADVRIDVTTGTRRGQLLRLLASVDHEIRRFVARYVSGEIRKPHIAAVRDIDVAARLDAAWPA
>NZ_CP006850.1|WP_038551077.1|7053052_7053829_-|isoprenyl-transferase
MLGGKVRNLPYRIYETQLSKQLAGKQHPRHVAVVCDGNRRWARENGFTDVTHGHRVGALKIAELVGWCQAEGIEMVTVYLLSTENLNRGADELETLFEVITDVVEELSAPENNWGVRIVGTLAGLPEDVARRMQKAADETHGRGGVHVNVAIGYGGRQEIADAVQSLVRQEIAAGETGEDLVQSITVNAIGQHLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEIWFTEAYWPEFRRVDFLRALRDYAARHRRYGI
>NZ_CP006850.1|WP_051495182.1|7054149_7054773_+|hemolysin-III-family-protein
MRGWIHTYAVGIAAVAVAVLVAVAATVSATAGWSTLIYGLTVCGLFGVSAVYHRVTWRTDRARTHMKRADHSMIFLFIAGSYTPFALLGLPGRTGITLLSVVWIGAVAGVALKLLWPTAPRWVGVPLYLVLGWAIVPVAAPLTHNVGVAPMVLLLIGGIAYSAGAILYATKWPNPWPEVFGHHEFFHAATVLAALCHYVAIWLVVLS
>NZ_CP006850.1|WP_025352637.1|7054877_7056401_+|HAMP-domain-containing-protein
MTSRLVLWALRARWGLSTVVMACNLGGLAVIIVELWLSGFLGNLGEEWFRTASQTAIYPILGAVAGIILAVRDRVYYFGWIDQTRRPTRPEAERLLKLPIAITSRALAIWIPGVFIATALFAQVVPTRALWAIGAMFFLGALESAGFTFLVVDRLIRPTIPVIARVLGGTSHWSATVLNRLVVSWAVAGAMPLLMLITVLGDPVADAGDRVRTALYMSLVGLLVGALTTATLARSVAAPLHALRRALDRIARGELSARVPITSASEIGRLELSVNELAENLSERERMRDVFGRHVGNEVAERALSGGVDLTGDVRVVTALFVDVTGSVELSTELAPREFVEKLNRLLAVVVSATEDNGGLVNKFEGDAALCIFGAPIALGDNATPALRAARRIRDEVALGGEFDIGIGVARGSVFAGDVGTDTRLEFTVIGDAVNEASRLTTEAKEVPRRILASQAVIEAATESERSRWVLYEKIQLRGRKEPTAGWTDRKPVGRVEPRVPATAADS
>NZ_CP006850.1|WP_081769538.1|7058606_7059545_-|NAD(P)-dependent-oxidoreductase
MKRPTRSARSVLNMAESHDVVVLGCGLMGSALARAFAAGGYSTAAWNRTHERAEALTADGVRAITDVREAVASAPLIVTCVTDYGATLEAFGNIADLAGKTVVNLGSGAPDEVVAFEAAMAERGGESVDGSIICYPQSIGTAEGAIVYSGSPETWARHEKTLMTLGGSSAYVSDLVTASSVLNIALVGAFFVASLSAFVEATSYVLKEGVDPALLAAMTPITLDFLGRTAADAITEIATGQYETDQATIDTYLAGLEPALVCIEAAGLQTRVIDAAVENLRAASAAGFGSRGFAAHAEILARRTPAFDGSRA
>NZ_CP006850.1|WP_025352639.1|7060403_7061819_-|malate-dehydrogenase-(quinone)
MAYTAKPSVPEEIYDVLLIGGGIMSTTLGAMLAKTCPERSVILFERLGELAAESSNAWNNAGTGHSGLCELNYMPDPADPSKAARIGELFQLSRQFWSALVADGDIADLFLTPAPHMDVVFGDRDVDYLRKRYETLRELPLFSAMRYTEDPAVIAEWAPLVAAGRDGAEPMAATRYEAGTDVDFGTLTGALAGVMKSSGARIRLGHEVTGLHRDPDGVWTVTVRNRATKRRFTVRARFVFVGAGGYALKLLQKARVPEVRGYAVFPFGAQFFRTADPRVVAQHDAKIYGQAPLGAPPMSVPHLDKRTVDGRDSLLFGPYATFSTRLLKHGRLTDLFTTLRPHNIAVLLAVGVQNLSLVRYLIGQLLSTRRRKFAHLQRFYPTATPADWDLIQAGQRAQLVKPDVRRIGTLTFGTETVVAANGTIAGLLGASPGASTAPAIMIDVLARCFPDEKSRWEPVLRAMMPALTDAA
>NZ_CP006850.1|WP_025352640.1|7061909_7062821_+|LysR-family-transcriptional-regulator
MDDFSPTQVEALIPLLAAFDAAASLGHITRASEALGVPQSSLSRRLKAVEKIVGTPLFQPMGRGIALTPAGRELFERTRGLVRTLGDAVRVVRGDADPEGGLVRFGFPLTLGPVSVPSMLADFHAGAPRIRLHLVQAHGEGLAELLREGRLDLAVMIPAPADLPATVLGHQRIHLYVARDHRLADRHTVDLAELADETFIANPPAYHLRRLLDSWCAEAGFAPEVAFEITEFETLRSLVAHGLGIALLPAPELEHPELRRIELSGPRARSIALASAAHRPTPAVARLHDYIARHATTHLATTW
>NZ_CP006850.1|WP_158436404.1|7062979_7063141_+|hypothetical-protein
MDDTMRNRSAGRRRPWFADLEEAERRGAHGNAGLGYFDCDCEICHRRFRPAAV

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Crispr_ID: NZ_CP006850_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_15

7152530-7152643

Orphan

Consensus_repeat	Method
ACGCAGGCTGCCGCCTCCGGCCGCGTCGCTGCAGTCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_15

>merge|NZ_CP006850|15|7152530-7152643|CRISPRCasFinder
ACGCAGGCTGCCGCCTCCGGCCGCGTCGCTGCAGTCGCAGAATTCGATTGCGACTTTCGCGGCGGCCTCCGTGGTTACGCAGGCTGCCGCCTCCGGCCGCGTCGCTGCAGTCGC

>NZ_CP006850|15|15|7152530-7152643|CRISPRCasFinder
ACGCAGGCTGCCGCCTCCGGCCGCGTCGCTGCAGTCGC	AGAATTCGATTGCGACTTTCGCGGCGGCCTCCGTGGTT
ACGCAGGCTGCCGCCTCCGGCCGCGTCGCTGCAGTCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025352725.1\|7158322_7159252_-\|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase	unknown	unknown	gnl\|CDD\|235110
NZ_CP006850.1\|WP_025352726.1\|7159492_7159699_+\|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl\|CDD\|238219
NZ_CP006850.1\|WP_025352723.1\|7155107_7156904_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP006850.1\|WP_038551094.1\|7154064_7154970_+\|DUF4393-domain-containing-protein	unknown	unknown	gnl\|CDD\|379564
NZ_CP006850.1\|WP_051495187.1\|7144900_7146007_-\|ADP-ribosylglycohydrolase-family-protein	unknown	unknown	gnl\|CDD\|377122
NZ_CP006850.1\|WP_025352729.1\|7162967_7163516_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352724.1\|7157370_7158219_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274680
NZ_CP006850.1\|WP_025352727.1\|7159700_7160588_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025352730.1\|7163681_7164029_-\|DUF1330-domain-containing-protein	unknown	unknown	gnl\|CDD\|377765
NZ_CP006850.1\|WP_025352728.1\|7160584_7162822_+\|copper-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NZ_CP006850.1\|WP_025352717.1\|7148481_7149036_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP006850.1\|WP_025352716.1\|7147474_7148137_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|153251
NZ_CP006850.1\|WP_025352719.1\|7150803_7151361_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|379275
NZ_CP006850.1\|WP_038551092.1\|7149176_7150796_+\|peptide-chain-release-factor-3	unknown	unknown	gnl\|CDD\|226593
NZ_CP006850.1\|WP_025352715.1\|7146624_7147227_-\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_CP006850.1\|WP_025352720.1\|7151450_7151924_-\|DUF4393-domain-containing-protein	unknown	unknown	gnl\|CDD\|379564
NZ_CP006850.1\|WP_025352714.1\|7146023_7146602_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP006850.1\|WP_025352712.1\|7143695_7144892_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|99746
NZ_CP006850.1\|WP_081769548.1\|7152751_7154074_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226834
NZ_CP006850.1\|WP_025352711.1\|7142045_7143332_-\|ergothioneine-biosynthesis-glutamate--cysteine-ligase-EgtA	unknown	unknown	gnl\|CDD\|274583

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025352725.1\|7158322_7159252_-\|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase	gnl\|CDD\|235110	PRK03188, PRK03188, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional.	4.47333e-165
NZ_CP006850.1\|WP_025352726.1\|7159492_7159699_+\|heavy-metal-associated-domain-containing-protein	gnl\|CDD\|238219	cd00371, HMA, Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain contains two cysteine residues that are important in binding and transfer of metal ions, such as copper, cadmium, cobalt and zinc. In the case of copper, stoichiometry of binding is one Cu+ ion per binding domain. Repeats of the HMA domain in copper chaperone has been associated with Menkes/Wilson disease due to binding of multiple copper ions.	6.89508e-15
NZ_CP006850.1\|WP_025352723.1\|7155107_7156904_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	6.94667e-175
NZ_CP006850.1\|WP_038551094.1\|7154064_7154970_+\|DUF4393-domain-containing-protein	gnl\|CDD\|379564	pfam14337, DUF4393, Domain of unknown function (DUF4393). This family of proteins is found in bacteria, archaea and viruses. Proteins in this family are typically between 254 and 285 amino acids in length.	8.64006e-21
NZ_CP006850.1\|WP_051495187.1\|7144900_7146007_-\|ADP-ribosylglycohydrolase-family-protein	gnl\|CDD\|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	9.79569e-61
NZ_CP006850.1\|WP_025352724.1\|7157370_7158219_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274680	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a domain found in a distinctive subset of bacterial luciferase homologs, found only in F420-biosynthesizing members of the Actinobacteria. [Unknown function, Enzymes of unknown specificity].	9.32919e-38
NZ_CP006850.1\|WP_025352730.1\|7163681_7164029_-\|DUF1330-domain-containing-protein	gnl\|CDD\|377765	pfam07045, DUF1330, Domain of unknown function (DUF1330). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	2.9675e-29
NZ_CP006850.1\|WP_025352728.1\|7160584_7162822_+\|copper-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP006850.1\|WP_025352717.1\|7148481_7149036_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.11897e-08
NZ_CP006850.1\|WP_025352716.1\|7147474_7148137_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	1.56219e-45
NZ_CP006850.1\|WP_025352719.1\|7150803_7151361_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|379275	pfam13577, SnoaL_4, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	8.51524e-30
NZ_CP006850.1\|WP_038551092.1\|7149176_7150796_+\|peptide-chain-release-factor-3	gnl\|CDD\|226593	COG4108, PrfC, Peptide chain release factor RF-3 [Translation, ribosomal structure and biogenesis].	0
NZ_CP006850.1\|WP_025352715.1\|7146624_7147227_-\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	2.68791e-64
NZ_CP006850.1\|WP_025352720.1\|7151450_7151924_-\|DUF4393-domain-containing-protein	gnl\|CDD\|379564	pfam14337, DUF4393, Domain of unknown function (DUF4393). This family of proteins is found in bacteria, archaea and viruses. Proteins in this family are typically between 254 and 285 amino acids in length.	1.58497e-22
NZ_CP006850.1\|WP_025352714.1\|7146023_7146602_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	3.9358e-102
NZ_CP006850.1\|WP_025352712.1\|7143695_7144892_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|99746	cd06453, SufS_like, Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.	2.72474e-95
NZ_CP006850.1\|WP_081769548.1\|7152751_7154074_+\|hypothetical-protein	gnl\|CDD\|226834	COG4399, COG4399, Uncharacterized protein conserved in bacteria [Function unknown].	2.23622e-06
NZ_CP006850.1\|WP_025352711.1\|7142045_7143332_-\|ergothioneine-biosynthesis-glutamate--cysteine-ligase-EgtA	gnl\|CDD\|274583	TIGR03444, EgtA_Cys_ligase, ergothioneine biosynthesis glutamate--cysteine ligase EgtA. Members of this bacterial protein family, EgtA, resemble the glutamate--cysteine ligase of the two-step pathway for glutathione (GSH) biosynthesis, but instead are involved in the biosynthesis of the histidine-derived thiol, ergothioneine (EGT). Successful in vitro reconstitution of EGT biosynthesis using EgtBCDE and gamma-L-glutamyl-L-cysteine suggests that this enzyme is a bone fide glutamate--cysteine ligase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	1.8416e-138

>NZ_CP006850.1|WP_025352720.1|7151450_7151924_-|DUF4393-domain-containing-protein
MRRRGDNLLARSADVYFTEEVHPAYDRILDQLASDEARILRFMAINGPQPSVDVRTNRPLGIGSELVEGDLTSVPEQAGVRYPDRSRLYLINLNRLGLLTTSDDPVVLSRYMVLEVQPIVEAALKQAGRVPKIVRKSLRLTEFGEDFCKTCFTINGS
>NZ_CP006850.1|WP_025352719.1|7150803_7151361_-|nuclear-transport-factor-2-family-protein
MDPDAVSAISRLKFRYLRALDTKSWEDFADTMIPEATATYSEYLQFESRDAFLAFMRNTLGPHVITEHRCDHPEIDIEGDAATGTWYLADTVLIPGHNMLLRGAAFYNDRYVRCDDGRWRIAHTGYERTYEVVLSLSDLPSLRLTASRWGVITGEPGTVPDIPAVVSDIEDIPVRPEQEPDEAIG
>NZ_CP006850.1|WP_038551092.1|7149176_7150796_+|peptide-chain-release-factor-3
MNSPAASTTTSGRVAQEAERRRTFAVISHPDAGKSTLTEALALHAKMISEAGAIHGKSGRKSTVSDWMEMEKARGISVSSTALQFEYDECVINLVDTPGHSDFSEDTYRVLTAVDAAVMLIDAAKGLEPQTLKLFQVCRHRGIPVITVINKWDRPGRAPLELLDEISERIGLTPTPLFLPVGIAGDFRGLLRRGDEGAATEYIHFTRTAGGATIAPEESFSPEQAAAREGEPWDTAAEESELLSATGQDHDQELFLAGQTSPVIYASAMLNFGVRQILDTLVALAPPPGPRADIAGGEREPADPFSAVVFKVQAGMDAAHRDRLAFMRIVSGEFERGMVVTHAQTGRPFATKYALTVFGRERATVDTAYPGDVVGLVNATALAPGHTLFVDKKVEFPPIPSFAPEHFATLRARSAGKYKQFRKAIDQLDSEGVVQVLRNDVRGDASPVLAAVGPMQFEVVTARMQAEFNVETQLDFLPYQLARRTDTDSAPELDRQRGVEVFTRTDGVILALFSDKWRLQYIQKELSELTLEPLVATAD
>NZ_CP006850.1|WP_025352717.1|7148481_7149036_+|TetR/AcrR-family-transcriptional-regulator
MGVDVPVRERLVSAGVDLLEQVGAAQLGLRAIAREAGVSHGAPRRYFPTHNSLLAGIAVRGFADLTTRFAAHDQEPPRVRIDRMAGEYIDFAQRRPEMFTLMFRHDLLQGSGENLRRRTLPIYRAWVDLVAECAPDRPGERAFGLWTNVHGIATLVANRSVELIAPGIGLDALVRDTVELHMSA
>NZ_CP006850.1|WP_025352716.1|7147474_7148137_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MWYWILKFVLVGPVLRILGRPEVEGLQHIPKDGPVIIAANHLAAIDSLYLALVLPRRITFLAKSQYFDEPGWRGRLNRWVMTATGQVRVDRTGGSASADALAAAVGILASGGVWGIHPEGTRSPDGRVYRGRTGVIRVAMQTGAPVVPVALTGTDRVNRRDRRLLRFGKVRIVFGAPRRFEPVDRAAVRAATDDLMVELAMRSGRRYVDCYAATFRAESA
>NZ_CP006850.1|WP_025352715.1|7146624_7147227_-|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MSDVSVLEATTRTEFGKGAARRTRRDGNVPAVLYGHGEAPKHVSVNAQAFAAILREHGTNAIVDLQIDGKKQLAMTKSVVVHPIRRYIEHADLLIVKRGEKVVVDVPVALSGDAAPGTLVTQEITTLSVEADALKLPESIEVSVEGVEAGTQITAGQIELPKGTTLAGDPEQLIVNIIVAPAAEAAEGEGEAEVEAESAE
>NZ_CP006850.1|WP_025352714.1|7146023_7146602_-|aminoacyl-tRNA-hydrolase
MTDSTAPALVVGLGNPGTEYERTRHNAGFLVADVLAERIGGRFTVHKKSGADLLEARLDGRKILLAKPRSYMNLSGRPVAALARFFSVPPTEVIVVHDELDLPFGSIRLKRGGGEGGHNGLRSISNALSTKDYLRVRFGVGRPPGRQDPADFVLKPFSAAERKEVPVLVEQTADAVELLLRVGLETAQNQLH
>NZ_CP006850.1|WP_051495187.1|7144900_7146007_-|ADP-ribosylglycohydrolase-family-protein
MPDVQDHTTIFDRYRGVLLGGAVGDALGWPIEFLKLEQIRDRFGADGLTDFAPAASDSALKHITDDTQMSLFTAEGLLRCAPGADPVPVLRRAYLRWLRTQREPEPDSRPDGWLAGLPYLYAVRAPGNACMGGLNRQQAQYIPPHPFGTPGPVNPDSKGCGTVMRSAPFGLAALGPESAFELAARCAQLTHGHPTGYAAAGAFAALIDRVVAGAALRTAVHDTIVQAANCPGGAETAAALNRAVAAADAGPATSEGVETVGEGWVAEECLAIAVYCALAAERSGDLRGALLLSVNHSGDSDSTGAVAGNLLGACYGLTALPLDWCGAVEGRDDLARVADDLVANFVYGDRAPLGDRYPLEVVEEAVPQ
>NZ_CP006850.1|WP_025352712.1|7143695_7144892_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MLDIHRLRADIPAYADPAGPPPVFLDSAGSSLPPRVVIDTITAHLRRESEIGGYRAASERLGDLADVKAAIGALINADPAAIALSDSASRAWSDFFYAVPLHPGDRILISGSDYASNAIAALQRARATGATVEPIPSDATGRIDLAALAEMLDDRVKVVSLLHVPTNGGLVNPVADATRIAHRVGALVLLDACQSAGQLPLDVAELGVDAMSATGRKWLRGPRGTGFLYVRPQVCRELEPSRLDLHSAAWTGPQEYRIADDATRFEFWECDVAARLGLGAAVRYLLDLGPDNVFAAVAANAGYLREHLPAVRGATVRDLGTEHSGIVSFTIDGLDPIEIRDRLRESDITVTVSHRGSTLLDMSARHLDSVVRASPHCFVTTAELDRFLAAVERLAPPR
>NZ_CP006850.1|WP_025352711.1|7142045_7143332_-|ergothioneine-biosynthesis-glutamate--cysteine-ligase-EgtA
MAVTVDTAPAEPGAGLSSRAAAEAYVGGVCFKQGPPALIGAELEWLTVCTESSAPDSRPRPSTLAEALGPYAPQSISPDSPAKILPGGSRITLEPGGQIELSSAPFDDASQLCAQLLEDSRFLSGLLATRSITTVAAAADADRQARRVLRLPRYRAMERSFAGVGPYGKLMMCNTAATQVSVDAGADSAEIVARWNALYAAGPALVAAFACSPRLQGAPVGTWASQRMRTWLRLDHTRTRPPVRQWADPIADYGRWALDVPLLCVRRGESEEDWAAPPGASFADWLCGALDEEVGRRPELADLDYHLTTIFPPVRASGHLEIRYLDAQPEDQWAVPIHVVDALMSAPAVVASATELARPVADEWASAARCGLADPQIRAAAVDLLNLAAEHARTPEAAEQIAAAARRCRDGRTPTGSIARCEPAEDAE
>NZ_CP006850.1|WP_081769548.1|7152751_7154074_+|hypothetical-protein
MLDRLLGFHPTILLELITIPLFTGVIGYITNWTGILMLFKPIRFHGFAMPGLKWLFPYLPKRIQVLPLLQYDGRMGWQGIVPSRADKMASIAVDKGLSKLGSVADFYRELEPDELAAHLTDMAQSQIREIVEDIARREHPQLWYNLPASVRELVHERVREQLPEILKELTDELGSNIEQLLDVKQMVIRYFQSRPQLLNTVFQVLGAKELRFMQNFGFYFGAPMGLVLVAVLHLTHWSPLVVLPVGGVIIGWVVNWIGLNMIFAPAYPKWWCPWRQGLLIKRQPEITEGYAELVATQIITIANVGDELLNGPRSDRTMQILEDTLRPATDRALGPMRGALRFVIGNRDYATLQSRFTDEAKSLAPVAFADPSFNAQQSHQVSRYIAKQMAALKPPDFVDMLRAAIKQDEWLLFVHGGVLGLIAGYAHLLIFGTEVANVWL
>NZ_CP006850.1|WP_038551094.1|7154064_7154970_+|DUF4393-domain-containing-protein
MAVSGPGSAPENDGGAEFSDENETASGTEVEEAIDDAEYSTELVRRPSAAVVVADPGPVGPIRATTGVVRVALSAVTGVASWGLGTAVGVTATVVRGSMAGQPPQRVLSEAGDQVRDSVRRALGIDGARRGAPVTSEGPSLRERGAELLRRSADVHGEDADHPAFDRILAELAPDEARILRFLYLDGPQPALDIRTGRALSTGTQRIEVGMSLIGEAAALRYPERAVTYLTNLRRLGLITVDGDQLDNPARYQLLESQPEVRRLLKRGFGTKVNYRSIALLAFGTDFTCACLPVPPLGQVL
>NZ_CP006850.1|WP_025352723.1|7155107_7156904_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MANLINLEQVHKSFGITPLLDNVSLGVQEGERIGVVGLNGGGKTTLLEVLTGIEAPDSGRVSRINGLRMAVVTQRGVLPEGATVGEVVLAGLAEDARTDGVAEHEWAANPRIRSVLEGIGIADLGMDSSVSNLSGGERRRVALAAALVRELDLLVLDEPTNHLDVEGVQWLAEHLLARRSALVVVTHDRWFLDTVATRTWEVVGGKVESYEGGYNDWIFARAERARQADASEARRRNLARKELAWLRRGPQARTSKPRYRVEAAEALIADVPPPRDNVQLASFARKRLGRVVIELEDATLATPDGRELVRDLTWRLAPGERVGLVGVNGSGKTTLLRALAGDADPVAGKRIQGQTVRIGWLRQELDDLPTDMRVLEAVSDVAERTMLGDREISAGQLAERLGFTPAKQRTPVGDLSGGERRRLQLTRILMAEPNVLLLDEPTNDLDIDTLQQLEDLLDGWPGTLVVISHDRYLIERISDSTWALFGDGKLTNLPGGIEEYLRKRAAAVSARRPSTPAPAENSTPTTDSAAYRAARKEFGRLERALEKLTEREEKLHVALAEAATDPDKLVSLGSELKQVQAEKESTETRWLELAEEVG
>NZ_CP006850.1|WP_025352724.1|7157370_7158219_+|LLM-class-flavin-dependent-oxidoreductase
MEVGIGLPIGDPESLTEWARRAEGGPFSTLGLLDRLVYDNPEPLVTLAHLAGATERIRLQTEVLIAPLREPVLLAKQVATLDRLARGRFTLGVGVGGRADDHEASGTELRTRGKRLDAHIATMRRLWSGEPYSDSCAGIGPLPRTPGGPELLFGGFQPVALERVARWGGGLLAAAPPEWAPRLFDTVRRFWAEYDRPGSPRIVAQVNAALGPQDVIDDARARMSAYYAFSDHGANMVNGMLTEPDQIRTVTRQFTDLGADEVIFYCYGRDPEQVDRLADVLG
>NZ_CP006850.1|WP_025352725.1|7158322_7159252_-|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase
MLSVVPSSVVVRAPSKVNLHLGVGDLRGDGYHELTTVFQALSLADDVRISPAGSLAVTVQGEGAAQVPTDRTNLVWQAAVRLGHLAGRAPLVEIAIDKGIPVAGGMAGGSADAAATLVGLNELWNLEMSRDELATVAAELGSDVPFALHGGTALGRGRGEQLLPVLSRNTFHWVLALAKDGLPTPRVFGELDRLRENGDPPRLGDPQELLQALASGDASQLAPLLGNDLQAAALSLNPALRRTLRAGVEAGALAGIVSGSGPTCAFLCGSETAAVAVSAELAGAGVCRSVRTATGPVPGARVLDAAGRH
>NZ_CP006850.1|WP_025352726.1|7159492_7159699_+|heavy-metal-associated-domain-containing-protein
MATSTYTVTGMTCGHCVASVQKEIGKLDGVTGVEVDLASGRVEVESAAPLAPADVVAAVDEAGYEVAS
>NZ_CP006850.1|WP_025352727.1|7159700_7160588_+|hypothetical-protein
MNDRLKFAAFGGGLVVLFGAAFGIGSLTGDPAGPATGHSSATGEATSTGLQATAAGYTLTALNAPATTGTPGSLRFRIDGPDGAPVTAYTDLHEKDLHLIVVRSDTTEYRHVHPVRDAAGTWSIDWTWRQPGTYRVFADSQPVGAPGELVLSSTVTVPGPATDAPLPPVSRTTTVDGYRVRLDGDLSTGGSEVSFVIEKNGKPVTDLQPYLGAYGHLVALRSSDLSYLHVHPEGEVGSAPAGPRVAFHAQAPSVAAYRLYLDFAHDGKVHTAEFTADAIGGPGPNTHDQHGGGHQ
>NZ_CP006850.1|WP_025352728.1|7160584_7162822_+|copper-translocating-P-type-ATPase
MSAPTTERSVELDIGGMTCASCAARIEKKLNRIDGVSATVNYATEKAKVSFPESVTPDELIERVVDTGYTATVHDNRPPEDSENTVAEANSPLRALRDRLLLSLALSIPVIALAMIPALQFRNWQWLSLTLATPVVFWGGAAFHRAAWINARHATATMDTLISLGTLSAYAWSVYALFFGDAGMPGMKHGFSFAVERSASASNIYFEVAAGVIVFILAGRYFETRAKDRAGSALRALLELGAKDVAVLRDGAEHRIPVAELRVGDLFLVRPGEKVATDGVVTDGSSALDLSMLTGESVPVEVGPGDAVIGATVNAGGVLTVRATRIGADTQLAQMAALVEDAQNGKAPVQRLADRVAGVFVPIVIAISVATLGFWLGSGAAVAVAFGAAVAVLIIACPCALGLATPTALLVGTGRGAQLGILIKGPQVLESTRRIDTVVLDKTGTVTTGTMSLAEIVPAEGQDADELLTVAAAVEHGSEHPVARAVVRGATERGLTGEPVRQFVSHGGKGVQGLVGERAVVVGRTELLADWSVPVPEALAQAKSEAERAGRTAIVVAWDGVARGVLVIADAIKSTSAEAIADMRALGLTPVLLTGDNAATARTVADQVGIDEVIAEVLPADKLDVVKRLQDQGKVVAMVGDGVNDAAALAQADLGLAMGTGTDVAIEAGDITLVRGDLRTVATAIRLSRATLRTIKGNLFWAFGYNVAAIPLAAAGLLNPMLAGAAMALSSVFVVSNSLRLRRFR
>NZ_CP006850.1|WP_025352729.1|7162967_7163516_+|hypothetical-protein
MTVLFGAGMAIWFASVAALFLARAVDGPTQRYFQLSLALCTVGSLALAISSPSVSGASTTRNVAVSSVFVAMAILCVYSVLMVRRRNAPPPPVRDPLAEIQSARDPLAEIQSTGDPVPATQTTREQLAAIQRDPLAAIQGTRDPLAAIQVTRDPFAATKTTRDPTSSIQRDPLAAIRARDTE
>NZ_CP006850.1|WP_025352730.1|7163681_7164029_-|DUF1330-domain-containing-protein
MSAYGFAHLRNRRPHPDILEYLERIQTTLDPFGGRFVIHGPPAEVVEGEWPGSMVLIEFPSLSEAREWYRSPAYQEILPLRADHIDGDLVLVEGVGPDYDPHVRALKLRGETPGA

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Crispr_ID: NZ_CP006850_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_16

7627578-7627677

Orphan

Consensus_repeat	Method
GCCGGTGAGCGACAATCGCGCAGCGGCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_16

>merge|NZ_CP006850|16|7627578-7627677|CRISPRCasFinder
GCCGGTGAGCGACAATCGCGCAGCGGCTCGTCGGCCCGACCGGGTGCGGGTGTCCCGCAGAACACAGCTGAGCCGGTGAGCGACAATCGCGTAGCGGCTC

>NZ_CP006850|16|16|7627578-7627677|CRISPRCasFinder
GCCGGTGAGCGACAATCGCGCAGCGGCTC	GTCGGCCCGACCGGGTGCGGGTGTCCCGCAGAACACAGCTGA
GCCGGTGAGCGACAATCGCGTAGCGGCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_025353048.1\|7627312_7627546_+\|BldC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133390
NZ_CP006850.1\|WP_081769561.1\|7625615_7626815_-\|PLP-dependent-cysteine-synthase-family-protein	unknown	unknown	gnl\|CDD\|223110
NZ_CP006850.1\|WP_025353052.1\|7630017_7630671_+\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|379311
NZ_CP006850.1\|WP_025353042.1\|7623380_7624250_+\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_CP006850.1\|WP_025353053.1\|7630705_7631716_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133415
NZ_CP006850.1\|WP_025353049.1\|7627833_7628037_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234992
NZ_CP006850.1\|WP_038551195.1\|7633977_7634646_-\|DUF899-domain-containing-protein	unknown	unknown	gnl\|CDD\|377584
NZ_CP006850.1\|WP_025353044.1\|7624729_7625314_-\|Clp-protease	unknown	unknown	gnl\|CDD\|214361
NZ_CP006850.1\|WP_025353047.1\|7626750_7627089_-\|DUF4229-domain-containing-protein	unknown	unknown	gnl\|CDD\|379415
NZ_CP006850.1\|WP_025353039.1\|7617824_7618841_+\|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|130256
NZ_CP006850.1\|WP_025353041.1\|7619810_7623227_-\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|226418
NZ_CP006850.1\|WP_025353056.1\|7634906_7635578_+\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|153251
NZ_CP006850.1\|WP_038551193.1\|7633529_7633964_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025353055.1\|7633012_7633441_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NZ_CP006850.1\|WP_025353050.1\|7628040_7628952_-\|dihydrodipicolinate-synthase-family-protein	unknown	unknown	gnl\|CDD\|188637
NZ_CP006850.1\|WP_025353043.1\|7624254_7624644_-\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|224861
NZ_CP006850.1\|WP_025353045.1\|7625313_7625535_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_038555745.1\|7631784_7632945_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP006850.1\|WP_025353051.1\|7629058_7629955_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176115
NZ_CP006850.1\|WP_148307219.1\|7618998_7619733_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|130314

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_025353048.1\|7627312_7627546_+\|BldC-family-transcriptional-regulator	gnl\|CDD\|133390	cd04762, HTH_MerR-trunc, Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins. Proteins in this family mostly have a truncated helix-turn-helix (HTH) MerR-like domain. They lack a portion of the C-terminal region, called Wing 2 and the long dimerization helix that is typically present in MerR-like proteins. These truncated domains are found in response regulator receiver (REC) domain proteins (i.e., CheY), cytosine-C5 specific DNA methylases, IS607 transposase-like proteins, and RacA, a bacterial protein that anchors chromosomes to cell poles.	1.11515e-13
NZ_CP006850.1\|WP_081769561.1\|7625615_7626815_-\|PLP-dependent-cysteine-synthase-family-protein	gnl\|CDD\|223110	COG0031, CysK, Cysteine synthase [Amino acid transport and metabolism].	1.07405e-100
NZ_CP006850.1\|WP_025353052.1\|7630017_7630671_+\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	0.000660604
NZ_CP006850.1\|WP_025353042.1\|7623380_7624250_+\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	3.18837e-122
NZ_CP006850.1\|WP_025353053.1\|7630705_7631716_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133415	cd04788, HTH_NolA-AlbR, Helix-Turn-Helix DNA binding domain of the transcription regulators NolA and AlbR. Helix-turn-helix (HTH) transcription regulators NolA and AlbR, N-terminal domain. In Bradyrhizobium (Arachis) sp. NC92, NolA is required for efficient nodulation of host plants. In Xanthomonas albilineans, AlbR regulates the expression of the pathotoxin, albicidin. These proteins are putatively comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains are often unrelated and bind specific coactivator molecules. They share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	2.27262e-29
NZ_CP006850.1\|WP_025353049.1\|7627833_7628037_+\|hypothetical-protein	gnl\|CDD\|234992	PRK01919, tatB, Sec-independent protein translocase subunit TatB.	0.00096613
NZ_CP006850.1\|WP_038551195.1\|7633977_7634646_-\|DUF899-domain-containing-protein	gnl\|CDD\|377584	pfam05988, DUF899, Bacterial protein of unknown function (DUF899). This family consists of several uncharacterized bacterial proteins of unknown function.	1.83719e-92
NZ_CP006850.1\|WP_025353044.1\|7624729_7625314_-\|Clp-protease	gnl\|CDD\|214361	CHL00095, clpC, Clp protease ATP binding subunit.	3.80166e-09
NZ_CP006850.1\|WP_025353047.1\|7626750_7627089_-\|DUF4229-domain-containing-protein	gnl\|CDD\|379415	pfam14012, DUF4229, Protein of unknown function (DUF4229). This family of integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 95 and 122 amino acids in length.	2.28099e-16
NZ_CP006850.1\|WP_025353039.1\|7617824_7618841_+\|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein	gnl\|CDD\|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	4.18861e-117
NZ_CP006850.1\|WP_025353041.1\|7619810_7623227_-\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	4.81498e-39
NZ_CP006850.1\|WP_025353056.1\|7634906_7635578_+\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	6.17046e-54
NZ_CP006850.1\|WP_025353050.1\|7628040_7628952_-\|dihydrodipicolinate-synthase-family-protein	gnl\|CDD\|188637	cd00950, DHDPS, Dihydrodipicolinate synthase (DHDPS). Dihydrodipicolinate synthase (DHDPS) is a key enzyme in lysine biosynthesis. It catalyzes the aldol condensation of L-aspartate-beta- semialdehyde and pyruvate to dihydropicolinic acid via a Schiff base formation between pyruvate and a lysine residue. The functional enzyme is a homotetramer consisting of a dimer of dimers. DHDPS is member of dihydrodipicolinate synthase family that comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways.	9.3464e-89
NZ_CP006850.1\|WP_025353043.1\|7624254_7624644_-\|phage-holin-family-protein	gnl\|CDD\|224861	COG1950, COG1950, Predicted membrane protein [Function unknown].	6.58679e-22
NZ_CP006850.1\|WP_025353055.1\|7633012_7633441_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.20565e-08
NZ_CP006850.1\|WP_038555745.1\|7631784_7632945_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.18495e-07
NZ_CP006850.1\|WP_025353051.1\|7629058_7629955_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.03771e-48
NZ_CP006850.1\|WP_148307219.1\|7618998_7619733_+\|ABC-transporter-permease	gnl\|CDD\|130314	TIGR01247, drrB, daunorubicin resistance ABC transporter membrane protein. This model describes daunorubicin resistance ABC transporter, membrane associated protein in bacteria and archaea. The protein associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	2.61468e-17

>NZ_CP006850.1|WP_025353048.1|7627312_7627546_+|BldC-family-transcriptional-regulator
MTAITAASRTLGSVNGQEALLTPGQVAALFHVDPKTVTRWAHAGRLGSLRTPGGHRRFRESEVMQLLRSLTTEATRP
>NZ_CP006850.1|WP_025353047.1|7626750_7627089_-|DUF4229-domain-containing-protein
MSEASRPDDAASDRAPASAGRRLAGNLALYTLARLALVAVIAAIILVVANLVHVDIPLIVALLFALVVAMPLSLVLFKKLRTRVNEDIAAVDAKRRNDKANLRARMRGEEGR
>NZ_CP006850.1|WP_081769561.1|7625615_7626815_-|PLP-dependent-cysteine-synthase-family-protein
MRSAATTRRTCARGCGARRGGERQSRSGSSARPGAGGAVRYCDRSISREWVDDAVRLIEADAQRSADTHLLRYPLPPEWGVRLYLKDESTHPTGSLKHRLARSLFLYAICNGWVREGTTIVEASSGSTAISEAYFAKLLGLDFVSVVPAKTSPEKIALIEAQGGRCHFVERPPDIYTEAVRLASECDGHYMDQFTYAERATDWRGNNNIAESIYQQMVLETHPIPDWIVVGAGTGGTSATIGRYIRYRRHKTRLAVVDPENSAFYGGYEVGDADYQTGMPSRIEGIGRPRVEPSFIGQVVDRMIEVPDAASIAACRFAGEALGRRVGGSTGTNLWGAFAVIAEMLAAGREGSVVTLLCDGGDRYAGTYFNDEWVAAQGLDPTAAHAVLTEFAATGIWRG
>NZ_CP006850.1|WP_025353045.1|7625313_7625535_-|hypothetical-protein
MSEATTLAAAAGSPDPQVGLRAVLALRRLLERLEAIQVANARKQGWSWQAIADALEVSRQAVHQKYNRRGGIR
>NZ_CP006850.1|WP_025353044.1|7624729_7625314_-|Clp-protease
MFERFSKAARTAIVLAQEEARELRSPQIDVEHVLLGVVARPDAGVRKILTDNGITAEEIRDRLTTEVADEPLGADDAAALRSIGIDLEAVRDSVQATFGEDVFDEPPAAEKGRGRFRLGGIVNFGHIPFSKDAKKTLELSLREAITRGDDSIEQGHILLGILRAANPTTRELLGGADGIDRVRTAVHEALDRAA
>NZ_CP006850.1|WP_025353043.1|7624254_7624644_-|phage-holin-family-protein
MALLLRLAINALAIWLAAAWIGGIELKDPPDSGTGGKILVVVCVAVVFGLVNALIKPIVKLLSLPLVIVTLGLFLLVINALMLWLTAKITETTDYGLRIDGFWAALAGAVIVTVVNWVLGILVPEGGRD
>NZ_CP006850.1|WP_025353042.1|7623380_7624250_+|1,4-dihydroxy-2-naphthoate-polyprenyltransferase
MASAAQWLEGARPRTLPNAIAPVLVGTGAAASLDAAVWWKALLSLLVSLALIIGVNFANDYSDGIRGTDDERVGPLRLVGSGLASPAAVRGAAFACLGVGAIFGLILVFTTAWWLLLIGAACLAGAWFYTGGSKPYGYSGFGEIAVFVFFGLIAVLGTEFVQAERVEWAGLVGAVAVGAFSSAVLVTNNLRDIPTDSVTGKTTLAVKLGDTRTRTLHLVLMAVPFIATLALTVRTPWALAGLLAIPLAVRSNAPVRGGEQGPGLIPSLRDTGLAMLAWSLLTALALSIG
>NZ_CP006850.1|WP_025353041.1|7619810_7623227_-|winged-helix-turn-helix-domain-containing-protein
MFSDHSGSADTSAHTRPDGRGPALSGIRVAVLGEIALRRDADLVTVPGARARLLVAALAVQPGRSRSAQALIDDVWGEQPPRAPMNALHTQVSRLRSALPEGALEIGPAGYRLLMNSDQVDLSMAQVLEREARQRLESGDSAGCLDRVLRARGLWRGEPGADLPPGPVADEVRELAAARASALDVLELSARESAGDIEGALRVARRSAAVEPLDEPAHATLMRLLATDGRANEALEVFAGLRTRLGEELGTDPGPALVALNTSILRGDQPPPRPAPASAVQRVSSAQHALTPEDRPEPTAALPNTALGLRAAPNPLLGRESDLRELEKLVGEFRVTTVLGPGGTGKTRVANELGLRLSQRLPVTLVELASLRADSEGTPAERMTVTCAEIENAIGAVLGVNEYTRDTNVLRRNPTVDGKRRLREALSLRPMVLILDNCEHLIDAVAEVVADLVGSCEQLTVVATSRAPLAITAETVYPLPPLAIDAQGSPATELFVSRARAVRPSARLDPEVVARLCRTLDGLPLAIELAAARVRAMSVEEIESRLEHRFALLRSGDRSSPERHRTLHAVIEWSWNLLEPEQRVALRRLCRFPGGFTLRAAEFVAGGPDVLDAVAAVDGLVGQSLLTVLADDDAIDTRYRMLETVREFGEEQLSEAGEADLVMDRMCGWAREFVHDAVCAYDGPEQVRVVLSFAAELDNLLSVLRHALDTGDSGTIYTIFGPIAVLWVMRGAHMELMNWAPRVVAVPSPTGARPSGAADLEMLAHVFLAMHLAFADAGLRPLAIIRVRARRLLARDDLRPALRFLAELLCAPVVLGQAVRRLAAGTRVEDEMTRSLALMIRANLRENASYMAGSTRDAKQLLALVDGRDAWGTAMCCQHLGQIASQAARYEEAVGYYRRAAELMRELRCYEESVELSSFLAISMVGTGHLAEARRELELALGIVDDGVGVDEPVTAPNQRKAAVVAGLAELDLAEGHIERGLLAFRRSLELFGWPISVAGPGPGDIIVAAAVLDAHVLNDAVREVPTLALEIVRAAEERLTQFTDLPQIGGAAGALGSYLIHTGGDSRLGAELLAIAQKAVGRQDYSSMHWSRHLAVATERVGAEVIEAGQRAISGMSRHTAAVRFLTLLPDLERLLA
>NZ_CP006850.1|WP_148307219.1|7618998_7619733_+|ABC-transporter-permease
MTMAYRGILKIKHNPEQLFDVTIQPILFTALFAYIFGGAIGGSVHAYLPVLIPGILVQTVVLTSVVTGTQLREDMDKGVFDRFKSLPIARVSALAGALVADMVRYGLATTLTVVVGLILGYRPAGGVVGVVVAGLVVVFCSFAVSWIWALVGVTGKSAASVQGISMMIMFPLTFMSGAFALVSTMPGWMQAINKANPVYYMVNSCRELMNGNVYSSNLLWCLVGSVVVIAIFAPLAIRAYMRRA
>NZ_CP006850.1|WP_025353039.1|7617824_7618841_+|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein
MTSYAPAEALAIEADGLVKVFGEQRAVDGVSLAVPQGAVYGVLGPNGAGKTTTIRMLATLLRPDGGRARIFGRDVVAEPTAVRSLIGVTGQYASVDEKLSATENLMIFSRLLGLSRTDAKRKSAELLEEFGLTEAANKALENFSGGMRRRLDLAASLIATPPLLFLDEPTTGLDPRTRAQMWETIRRLVREGATVLLTTQYLDEADQLADRIAVIDRGKVIADGTSDELKSSVGQSALQITVADRTRIEQARTVIGDFLSRAEGKLVEAAISPEAGRITAPLSDPGVTADLLIRLRDNDVRVDEITVSKPSLDEVFFAITGHGAESEDTAAESETDAA
>NZ_CP006850.1|WP_025353049.1|7627833_7628037_+|hypothetical-protein
MAYLLALIAVVAVAVLCWKAFGPERMPRIGTGRTAGNRRRAIGPDDDPEFLWRISRQHRDGDPGSER
>NZ_CP006850.1|WP_025353050.1|7628040_7628952_-|dihydrodipicolinate-synthase-family-protein
MTFSGLFVPLITPFTERDEPAYDVLARLAAEALDAGASGIVALGTTAEPATLTAAERRSVVEVCAEVCLDRGAPLIVGTGGNSTAASERELAELDPRAAGALTVVPYYTKPSPAGVVEHFRRLAAVSPVPLVIYNVPHRTGRPLDAVTLCSLADVPNVAGFKHAVGAVDETTVAFLAAAAERTAVLSGDDLFTAPLLALGARGAILTCANVATAAYAALVAAWREGRVDAARRYGDVLVEPARALFAEPNPAVVKAVLAAQGRIPHAAVRLPLLPAGHDATAAALAALELLSDDVRTGAFALG
>NZ_CP006850.1|WP_025353051.1|7629058_7629955_+|LysR-family-transcriptional-regulator
MLDVRRLRLLRELFHRSTIAAVAEAVSYTPSAVSQQLSALEREAGVALLERSGRGVHLTPAARRLVEHTEAVLAILEQAEAELATAPAQLGGTLHIGAFPTAVQHILPDALVTLSRAHPRLELHVTELDPAGVPAALRTGVLDIALIQEYDYVPLPAEPGLHNEPFLEEPVYLAACSTEPLTAHRDSPWIAATPGTLCHTMTVRACEAAGFIPRIRHHTDDFGTVLALVDAGQGVAFVPELAIPPESENRTSAVELTALPIRRRTRIAYRAGTRDHPAVAAARIALHATQGTIPPAQP
>NZ_CP006850.1|WP_025353052.1|7630017_7630671_+|HEAT-repeat-domain-containing-protein
MNTTHREPDARLVAALAGPESSTRLRAALAAGTDGDVRLAEVLVARCAVEPDFFVRDMLTWALCRMPAEVTVPMLLAELDSGVAQARSQALHTLSKIGERSAWPQVAGMLHDADEEVALSAWRAGAALVPPGSEPVLAAELSKEFGRGSHSVQRSLSRALATLGDAADPVIDAAADSADPHIRAHAEATRRLRLDPESGFTLSLEFAKRVAATGTDG
>NZ_CP006850.1|WP_025353053.1|7630705_7631716_+|MerR-family-transcriptional-regulator
MLIGEVSRRSGVSTRMLRHYDRLGLVRPTGRTTGGYREYSTDDIRRLFHVESLRTLGLSLADTKRALDDADFAPGALVGDLIRHTRARIAAETELLAKLERVESAAPAQWEDVLNVITLLRALESNLGDHRQQAALAQYEGAALPVDALVEAALAEEDPNVAGALRWALARAGDAGLANLAAGLRSPDPDRRHRATVTIAEVPGTQATALLIEALNDSAVIVRDRAALALGARQVIDAVPALLEMIVTGRTDVEAAELLGLLAETPDADMIRNLRHELDIRTDPAARLRLTQALAEIPGTTAQLTALTEDSDPVIAGTAAAILRTRERRNRRSGPQ
>NZ_CP006850.1|WP_038555745.1|7631784_7632945_+|helix-turn-helix-transcriptional-regulator
MGEHVGRRIASERKIAGLGQRQLAARANYSLSMVKAVEQGREVASPGFVSAVARALHITPEQLTGAPYDDGKPLSDAVNGLSVLLAEGRFVRADEPGTLAQLESDLTAAQRLYRRDRTRQTIEVLPDLVRRLHGAVRELSGDEQARAYTLLTSAYLLAEWSVRRTGHMTLALPALELADGYAASADDSTFAPLSRLARARVLTHYGESDVAARLIDSAVEAGDSSRAGTVLAGYSHLAGAVNEARSLNYNGAMAHIESARELAARTGETDLYMTAFGPLNVEIHAHAIELESGDPNKAAVEGARLTHSPDAPPTRIAHHWQDNARAWLMSGKPDRALAALNKARAAAPQQTRLHPSVRETVYGIASVQRRQSEGLLGFASWLGAGL
>NZ_CP006850.1|WP_025353055.1|7633012_7633441_-|nuclear-transport-factor-2-family-protein
MSDETTTTRHTVQELLSRIGSGDPEAIAELYSPSCDWKLNWPESEHGRSATPWVRDHPTPADHYRTIADHHIPEEVGTIVEHILVDGPNAVVMGEIRQTARPTGNAYRARFALHLTVTDGLITRHHVYEDSLAVAQAFEPTT
>NZ_CP006850.1|WP_038551193.1|7633529_7633964_-|hypothetical-protein
MTIANFATLNGLEVEQVWVWKSYLRLVFDMGGGTAPAAYVDLTDFLYTDDTGEQEVRVEDDPRTAGPVLSLLNHRVTAAEVRNWELALTFDTGARIACPPDPDYEAWAACLPDNTSWFCPPGEFSVQTSTKFREFPMDRPGVHD
>NZ_CP006850.1|WP_038551195.1|7633977_7634646_-|DUF899-domain-containing-protein
MPAHEVGTREQWRSAYEDLRTQEKELTRRGDALARERQALPWVPVTKEYRFDTNAGVKTLPELFDGRSQLIIRHFMHGPKTPEGCPGCTFETDNLVGAVPHLAHRDVTFILASRSPLPTLNDYKSRFGWDIEWVSMGDNGFNEDFYEIMRTSSVKRPPGDMLDVMELMALSSFALADGQVYHTYSTYDRGTDALNATWQLLDRAPNGRGDNFDNWPRKRDEY
>NZ_CP006850.1|WP_025353056.1|7634906_7635578_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MSERERPRADRPKGLGKRAWLTTKFVRRILRTLAWSNFVHVTVVGRELVPKSGPVIVASNHISMLDAVFLWGALRRRAIAIAMAELWSWPVVGWLVRRLGHIPVVRRDNASGQSAMAQAEQILRYDGVLIIYPEGRLVSEGEHEPYKPGVAKLALATGVPIIPVGTTGTDRVLPLKRNRGDGPAFDRRQRVTIHFGTPVDPAEFDDPDKLLDHLRERIEELRT

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Crispr_ID: NZ_CP006850_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_17

7766437-7766526

Orphan

Consensus_repeat	Method
GACCGCGCACGCTCCAGGCGAGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_17

>merge|NZ_CP006850|17|7766437-7766526|CRISPRCasFinder
GACCGCGCACGCTCCAGGCGAGCGGCATACGAAAAGCACTCCCGACAACCACAAACCCCCAAAGGCGACCTCGCACGCTCCAGGCGAGCG

>NZ_CP006850|17|17|7766437-7766526|CRISPRCasFinder
GACCGCGCACGCTCCAGGCGAGCG	GCATACGAAAAGCACTCCCGACAACCACAAACCCCCAAAGGC
GACCTCGCACGCTCCAGGCGAGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_038555839.1\|7774924_7776379_-\|histidine-kinase	unknown	unknown	gnl\|CDD\|340419
NZ_CP006850.1\|WP_025353173.1\|7752048_7753656_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP006850.1\|WP_025353169.1\|7746856_7747291_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025353177.1\|7763822_7764596_-\|ethanolamine-ammonia-lyase-subunit-EutC	unknown	unknown	gnl\|CDD\|377583
NZ_CP006850.1\|WP_025353178.1\|7764592_7765996_-\|ethanolamine-ammonia-lyase-subunit-EutB	unknown	unknown	gnl\|CDD\|237897
NZ_CP006850.1\|WP_025353181.1\|7770870_7771746_-\|Clp-protease	unknown	unknown	gnl\|CDD\|214361
NZ_CP006850.1\|WP_025353184.1\|7773921_7774209_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|183194
NZ_CP006850.1\|WP_025353180.1\|7770135_7770429_-\|DUF222-domain-containing-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025353187.1\|7776403_7778077_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|381126
NZ_CP006850.1\|WP_025353172.1\|7749962_7752032_+\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224422
NZ_CP006850.1\|WP_025353175.1\|7754665_7756483_-\|NAD-binding-protein	unknown	unknown	gnl\|CDD\|223643
NZ_CP006850.1\|WP_081769566.1\|7766989_7768231_+\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|377164
NZ_CP006850.1\|WP_025353183.1\|7772979_7773861_-\|RNA-polymerase-sigma-70-factor	unknown	unknown	gnl\|CDD\|132002
NZ_CP006850.1\|WP_025353182.1\|7771798_7772884_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP006850.1\|WP_025353179.1\|7768307_7769933_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP006850.1\|WP_025353185.1\|7774326_7774755_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_081769565.1\|7748818_7749964_-\|membrane-dipeptidase	unknown	unknown	gnl\|CDD\|366534
NZ_CP006850.1\|WP_025353174.1\|7753740_7754601_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|227099
NZ_CP006850.1\|WP_025353170.1\|7747301_7748705_-\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|236106
NZ_CP006850.1\|WP_038555833.1\|7756548_7757154_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_038555839.1\|7774924_7776379_-\|histidine-kinase	gnl\|CDD\|340419	cd16943, HATPase_AtoS-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS. This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.	7.08585e-45
NZ_CP006850.1\|WP_025353173.1\|7752048_7753656_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.34186e-49
NZ_CP006850.1\|WP_025353177.1\|7763822_7764596_-\|ethanolamine-ammonia-lyase-subunit-EutC	gnl\|CDD\|377583	pfam05985, EutC, Ethanolamine ammonia-lyase light chain (EutC). This family consists of several bacterial ethanolamine ammonia-lyase light chain (EutC) EC:4.3.1.7 sequences. Ethanolamine ammonia-lyase is a bacterial enzyme that catalyzes the adenosylcobalamin-dependent conversion of certain vicinal amino alcohols to oxo compounds and ammonia.	5.63841e-103
NZ_CP006850.1\|WP_025353178.1\|7764592_7765996_-\|ethanolamine-ammonia-lyase-subunit-EutB	gnl\|CDD\|237897	PRK15067, PRK15067, ethanolamine ammonia-lyase subunit EutB.	0
NZ_CP006850.1\|WP_025353181.1\|7770870_7771746_-\|Clp-protease	gnl\|CDD\|214361	CHL00095, clpC, Clp protease ATP binding subunit.	9.81636e-25
NZ_CP006850.1\|WP_025353184.1\|7773921_7774209_-\|hypothetical-protein	gnl\|CDD\|183194	PRK11556, PRK11556, MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit.	0.00321422
NZ_CP006850.1\|WP_025353187.1\|7776403_7778077_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|381126	cd17595, REC_TrxB, phosphoacceptor receiver (REC) domain a fused response regulator with a thioredoxin reductase output domain. This family is composed of uncharacterized fusion proteins containing a REC domain and a thioredoxin reductase domain. Thioredoxin reductase catalyzes the reduction of thioredoxin and is thus a central component in the thioredoxin system. Fusion proteins containing REC and thioredoxin reductase domains could play an important role in the environmental regulation of the cellular dithiol-disulfide ratio. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.08015e-76
NZ_CP006850.1\|WP_025353172.1\|7749962_7752032_+\|S9-family-peptidase	gnl\|CDD\|224422	COG1505, COG1505, Serine proteases of the peptidase family S9A [Amino acid transport and metabolism].	0
NZ_CP006850.1\|WP_025353175.1\|7754665_7756483_-\|NAD-binding-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	2.25127e-23
NZ_CP006850.1\|WP_081769566.1\|7766989_7768231_+\|PepSY-domain-containing-protein	gnl\|CDD\|377164	pfam03929, PepSY_TM, PepSY-associated TM region. The PepSY_TM family is so named because it is an alignment of up to five transmembranes helices found in bacterial species some of which carry a nested PepSY domain, pfam03413.	4.29192e-36
NZ_CP006850.1\|WP_025353183.1\|7772979_7773861_-\|RNA-polymerase-sigma-70-factor	gnl\|CDD\|132002	TIGR02957, putative_sigma_factor, RNA polymerase sigma-70 factor, TIGR02957 family. This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.	1.95293e-116
NZ_CP006850.1\|WP_025353182.1\|7771798_7772884_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	1.8257e-69
NZ_CP006850.1\|WP_025353179.1\|7768307_7769933_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP006850.1\|WP_081769565.1\|7748818_7749964_-\|membrane-dipeptidase	gnl\|CDD\|366534	pfam01244, Peptidase_M19, Membrane dipeptidase (Peptidase family M19).	5.20465e-68
NZ_CP006850.1\|WP_025353174.1\|7753740_7754601_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|227099	COG4757, COG4757, Predicted alpha/beta hydrolase [General function prediction only].	3.5473e-33
NZ_CP006850.1\|WP_025353170.1\|7747301_7748705_-\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|236106	PRK07818, PRK07818, dihydrolipoamide dehydrogenase; Reviewed.	0
NZ_CP006850.1\|WP_038555833.1\|7756548_7757154_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.16518e-08

>NZ_CP006850.1|WP_025353178.1|7764592_7765996_-|ethanolamine-ammonia-lyase-subunit-EutB
MSVYRQRLAGVGYEFHGLVDLLGKATPRRSGDELAGCAAESDAERAAAQWALAELPLTTFLDEPVIPYETDEVTRLIIDGHDRAAFAPIAHLTVGDLRDRLLSAASAPDSATRLSPLAAGLTAEMAAAAAKIMRNQDLIAVSHALRVTSGFRTTVGLPGRLATRLQPNHPVDDPRGIAAAILDGLLLGCGDAVVGVNPASDSPARVGELLRLLDEIRARFDIPMQSCVLTHVTTTLDLIAAGAPVDLVFQSVAGTEAANRSFGVDLALLREAEAAGRSLNRGTVGGNVMYFETGQGSALSSGTHLGTGNRPVDQQTLEARAYAVARALNPLLVNTVVGFIGPEYLYNGKQIIRAGLEDQFCGKLLGLPMGVDVCYTNHAEADQDDMDTLLSLLVLAGTAFVITVPGADDIMLGYQSLSCHDALYARAVANLRPAPEFEDWLRRQGMADDAGRILPADLSTSPLRALA
>NZ_CP006850.1|WP_025353177.1|7763822_7764596_-|ethanolamine-ammonia-lyase-subunit-EutC
MNADPWDALRAHTQARIGLGRAGAGMPTRGHLELVAAHATARDAVHTPLDVPTLADQLRTLGIGDPLTIASAAPDRETYLLRPDLGRRPAPGVALPRIEAELGIAFCDGLSATALQTHGGELAREILAALPGWTVAPPVIATQARVALGDEIGSRLGVTTMLVLIGERPGLSAADSLGVYLTRHPRPGRTDAERNCVSNIRPPHGLDYPHAARIVAALAVGARRLGASGVALKDTSPAGELDTGVPPAATVKPTAAG
>NZ_CP006850.1|WP_038555833.1|7756548_7757154_-|TetR/AcrR-family-transcriptional-regulator
MYAGQPVEDRQRQRRARFLESGLTVFARDGYANSSVGAICKDAGLSSRQFYEEFTGRESLLLELYEQIDRESRDAVIAALDAHSEGSAIEIIDAGVRAYIEAIGRDPRKARVALVEVVGAGPKVEKFRLELRRSWGALLSGAAEDAALQGEIPSGDYEMRMLAIIGAVNYVVDEWSGSEPRRPLDEVIKVLRRIIMGAVSA
>NZ_CP006850.1|WP_025353175.1|7754665_7756483_-|NAD-binding-protein
MNVSPGGERSPTFVVCGDNPLVHQLALQLTTRFADATVTAVLPNRSGSYVPQLEKLTRVRILCAERLDESVLRDAGVERARALALVDQADVENFHTALRAHELNPRIRLVIRMFNTGLGFRIRRLFSDCVVLSISEMAAPSFIAAALGEDALDYLRLGERTLYVAAAGDAPPDRVIAGLAGGPGGITLRSARSPAGRVLALAERVPYSPSAPRRWLTLMRYLIAHDLIRLLMVLLVLIAGGCIMMVFIGNSWGTAAYETLLDAAGAAQPEPAREPMYKLLQLGVVFIGLTMTPVVTALVVGGVLRAQLADYHVDPSRMEDHVVVAGLGNVGMRVVEQLSDLGVPVVALDYDENARGIALARSLGVPVVIGQATWEDTLLAMGVPKARALVLLTSSDAVNLEAAMLGQSYRDDLQVVMRVSDDDLAERVQRTLGKAVVRSVFQLAAEGFAAAVVERNVIATLSLDHVALLVAEVPVEPGSALVGLRIAEIGLSEHSRVLAVQAAEGDTPEWLPSSQTVLRAGNQLVVVATRIGLNEFLERCAGEPDSEDAPEAGNSGNSGRGIALMEERAEVAHTGAGAGEVEASGDVVGTDAVTESDARRDLGGR
>NZ_CP006850.1|WP_025353174.1|7753740_7754601_-|alpha/beta-fold-hydrolase
METIPIQMPDGSTVPVRFVPASGPHRHPITADTPRPVVVIIPGLGVPGEYYTDFARELARRGFDIAIGELRGNGDSRPKPSAASAYGYHELVSVDFPAIFEAVRTRFPDSTPILLGHSMGGQLGVMYAARIRGRLAGLILIASGTPYYRGYGGIARSAMLVGPAAISLTANLAGFWPGDRITAGGFGRQSKVLIADWARLARTGRFVPVGADIDYDERIARLKLPVLSITMASDDLTPRSSAAHLLEKLPNARVSTWHEPKPLGHNGWIIDPESTVDRIEKWVRDL
>NZ_CP006850.1|WP_025353173.1|7752048_7753656_-|MFS-transporter
MTPRPGTATGSTLVLAVLGSGQFLMTLDSSVMNVSMATVASDIGTTITGIQTAITLYTLVMASLMVTGGKVGTILGRRRAFGVGLVIYGAGSLVTGLAPDLGVLLVGWSLLEGIGAALIMPAIVSLVAANFAEQRRAAAYGLVAAAGAMAVAVGPLVGGAVTTFASWRYVFFGEVVVVAAILLVLRRVADVPPQRVRLDLVGSALSILGLGAVVFGVLRSSEWGWIRPRPGGTSIAGLSPVIWLILGGLLVLYAFVRWQARLARSGREPLIDPGLFGNRRLGGGLAMFFAQFAVQAGVFFAVPLFLSVVLELSALETGVRILPLSVALVLAAVGIPKLRPRANPRRVVRLGLGIMIVGILLLAGGMDPGANAGVVSVPMLCMGFGLGALASQLGAVTVSAVPDAQSAEVGGLQNTATNLGASLGTALIGSILIATLTSSVIGGIENNPAVPATISQRASTELADGVPFLSNTQLQQSLDTAGVDPAAAQEIVAVNADARLQALQVAFAVTALLAVIALFFTGRLPRHAVGFSPDP
>NZ_CP006850.1|WP_025353172.1|7749962_7752032_+|S9-family-peptidase
MSGAEQSNDPYLWLEDVTGERALSWARAHNEVVVEQFATSDRFDDLDQRILAMLDTDTRIPYPTRRGPWLYNFWRDAEHPRGMWRRTTFDDYRTDDPAWDVLIDLDDLATAEGENWVWGGAAVLRPSQHLALISLSRGGADAKVIREFDLTTRQFRDPDGPERGFHLPEAKSQLRWIDADTVYVGTDFGPGSLTDSGYPRVVKRWRRGTPLSEARTVFEGEPGDVMVSAGYDRTPGYERHWVARATDFFNESVYLLDPDDTLRHIDAPSDASESWYKDWLLIQLKSPWEVAGHRYPAGALLAIDIDEFFAGARDFEIVFEPDAHTSLHGYGWTENHLLLITLEDVQTKLYVLTPAPRGAWSRQPLADTPPMATTSVMNLDPLESGDEFMLTTSGFTAPATLLAGSVGGTATPLKHETEYFDAAGLDTEQYFARSDDGTMVPYFVIRHRDHRGTPGPTVVSGYGGFEVSRTPGYSGASGMGWLERGGTWVMANIRGGGEYGPQWHTQAQKADRHKVYEDFSSVAKDLVARDITTAAQLGAVGGSNGGLLMGVMLTRYPELFGAIVCQVPLLDMKRYHLLLAGASWMAEYGDPDKPEEWAYISEYSPYQVATAADPARAYPPILLTTSTRDDRVHPGHARKMAALLESQGRTVWYHENIEGGHGGAADNKQMAFQSTLIYEFFTQMLMENA
>NZ_CP006850.1|WP_081769565.1|7748818_7749964_-|membrane-dipeptidase
MVHILAYRADVWSETDPRADVSRPGGGHGFVQLLTLVVKGGSVGPALWEQHCCLPVLPSADVTELARYPAGSYVSVNVGYSLHSMADALAMIELLRRDALADGRFRLVRTFADTEVAAVGPEAAVALAFDLEDSRPLDGDLDNVTRFHDLGVRSLLPTYNHANAAGGGCLDTDDRGLTGYGRDLIRTLGEVGVFADGSHCSRRTGLDIAEVSGGPMIYSHSNFAALWPHPRNITDDQARACAASGGVIGINGVGIFLGRNRVEGRAARIEAMADHIAYGAELVGVEHIGIGSDFSFDGDQFNAEIAAAPENFSEDYTRWGPLQWVPPEDLLGIDREGAGNSVDMAGVPSLDDALARKGFTEAERVKIFRGNFARVAREVWK
>NZ_CP006850.1|WP_025353170.1|7747301_7748705_-|dihydrolipoyl-dehydrogenase
MTSHYDVVVLGAGPGGYVAAIRAAQLGLRTAIVEQKYWGGVCLNVGCIPSKALLRNAELAHIFTKEAKTFGISGQASFDFGAAFDRSRKVADGRVKGVHFLMKKNKIDEFDGKGSFTDANTLSVALSSGGTETITFDNVIIATGTETKLLPGTSLSQNVVTYEEQILTRDLPGSILIVGAGAIGMEFGYVLKNYGVDVRIVEFLDRALPNEDADVSKEITKAYKKLGITITTGASVQSIEDNGSKVTVSIKDNKSGSVETVTVDKVLQAVGFAPRVQGYGLENTGVQLTERGAIAIDDYMRTNVPHIYAIGDVTAKLQLAHVAEAQGVVAAETIGGAETLALGDYRMMPRATFCQPQVASFGLTEQQARDEGYDVKVATFPFTANGKAHGLGDPTGFVKLVADAKYGELIGGHLIGPDVSELLPELTLAQKWDLTVNELARNVHTHPTLSEALQEAIHGLAGHMINF
>NZ_CP006850.1|WP_025353169.1|7746856_7747291_-|hypothetical-protein
MTNGPSSANMSGGGPLSRFRLGFAVGCCVTLLVAVAILALDTGLRRTSDLQRDTQPADVVYSDGSTHLAGVVEVRSWLFRRHVEYQVYTGRDPSMSYGHFVRIGMTGVEPPEFADVRWSGDGVRMRFRSGHELFVPAVEFVGGR
>NZ_CP006850.1|WP_081769566.1|7766989_7768231_+|PepSY-domain-containing-protein
MTDIETRSTARPAVRKRPRKPVRRALIVAHRWSALILGIVLVVQCTSGAALLYHTELFRASHSAFYRHTEGDALRNANGETDFDRALALVREEDPGFAAGWMGTDDGVIVVGDADFTEAYGIDPGTGRINDRIGLTGGVLGWLVNLHDCAFGCVRYAGAVPALNATVPLIGITWAATILGVMGLLLVVLTISGAVIWWPTLKRWRHGFRVRMSKGRFARDRDLHNVIGIVSVPFLLMWGITGAAIEMPVVEKAWLTITGGQADTALPQDVFHPRETPPERPAITAAEATRTATGEHPGRLAYLMLPTDAAPYYRAYVAGGYSPYEHRALYSGDVLVYVNARDAADTKVVDAAHDRPLANTFYAKVFEPAHFGWLVNGWWRLIWLVFGLTPLALAITSTSTWLFKRRTRRSKRA
>NZ_CP006850.1|WP_025353179.1|7768307_7769933_-|chaperonin-GroEL
MAKTIAYDEEARRGLERGLNSLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGLKRGIEKAVEAVTAKLLDTAKEVETKEQIAATAAISAGDASIGELIAEAMDKVGKEGVITVEESNTFGLQLELTEGMRFDKGYISGYFVTDAERQEAVLEDPYILLVGSKVSTVKDLLPLLEKVIQAGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAQLADIAILTGGEVVSEEVGLNLETATVDLLGTARKVVVTKDETTIVDGAGDADAIAGRVAQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVPGGGVALLQAGPALEDLKLTGDEATGANIVKVALAAPLKQIAFNAGLEPGVVAEKVANLPVGQGLNADSGVYEDLLAAGVADPVKVTRSALQNAASIAALFLTTEAVVADKPEKAAAPVGDPTGGMGGMDF
>NZ_CP006850.1|WP_025353180.1|7770135_7770429_-|DUF222-domain-containing-protein
MAGGADSDLIAGELRADLLRALSYVETEDGEDGSYIVNGDLPPEVAPPFIRAIMRIEAELLLHDAEQVTVERGEPRSPEERRTDAFVALALRVTDDT
>NZ_CP006850.1|WP_025353181.1|7770870_7771746_-|Clp-protease
MTQRIRLDDLIDGIKLARPDDVLQQLSEAVVVAGHMSEVADHLIGHFVDQARRSGASWTDIGQSMGVTKQAAQKRFVPKPGDAAMDPNAGFARFTPRARNVVMASMEEARRAGNAEIQPEHLVLGLLSESTALAAHAITAKGVSLDAVHRVATAALPPAVDEVPDLIPYTAAARKTLELTFREALRLGHNYIGTEHLLLALLEQEDGSGVLSGLGLTKDDMERDIAAQLSDFMPPNPITPPTPPQPPTPPAAPGFQVPPAPPGAQVPPVPPVPPHPPTPPVPPHPQTPPTP
>NZ_CP006850.1|WP_025353182.1|7771798_7772884_-|FAD-dependent-oxidoreductase
MTTPHRILVLGAGYAGLAAAGKLCRRPHGARITVVDARAELVERVRLHQLAAGQTVPRWDLRTLLERKGAEFVQGSVTAIDAATQEVSLSDGTILGYDTLIYTLGSSADADSVAGVRANAYPIATLEDIAALPSLSGRVAVVGGGATGIETAAELAESRPELSVALVSSEQPGHRLSERARRGIAAALRRLGVEVHSDAKVVEVTASGVVTADGDRIAAETVLWTTGFTTADLAARAGLAVDSHGRVLVDATLRTSDPHIYAAGDCAAITGPGGQELRMACATALPTGAQAASAALARMRGARPDELRFRYVLQCISLGRRAAVVQFVRADDAPTPRVLTGRPAAVVKELIVRGASLTARR
>NZ_CP006850.1|WP_025353183.1|7772979_7773861_-|RNA-polymerase-sigma-70-factor
MDDTGLAEFERHRPRLFALAYRMLGTAGDAEDAVQETYLRWDATERDEIRSSEAWLTTVVVNLCRTWLDSARSRRETYTGPWLPEPVPTGNGDLGPMESAEQRELVSLAVLTLLERLSPAERAVFVLREAFGYAHREIADMLELSEANSQQLYRRARQHVRSERPRFDAEPARARELFERFLAAARRGDVAALEAMFTADVVSLADGGGKMGAARHPIVGASRVARYLAGLFHRDVEGLELTVEEVNGAPAAVARVHGSMLLIGAVDGGPEGISAVRLIVNPDKLAYFGRVAA
>NZ_CP006850.1|WP_025353184.1|7773921_7774209_-|hypothetical-protein
MRKLTIAGLSAALVVLGLAAAAVIVWPTTSGADDQRVCCSPPSSSAATTTAATPEDGSGLRRNNSPSPSPAPTTEAPHFTLRIPWPKRDPGAADG
>NZ_CP006850.1|WP_025353185.1|7774326_7774755_-|hypothetical-protein
MKRLTVAAVALSALVVGLTACGSDDHSATDANGLRRNGSAVATSAPAAPPPTSAPEPSTPEAAPTTTEENSSLGPASRTTCDEFRKLDVEAEKSLMDRILAENPGSKFDGSPNVALGTAKLVCLAKSEAGKPVAVAIGVVSE
>NZ_CP006850.1|WP_038555839.1|7774924_7776379_-|histidine-kinase
MTGTRTLCDPAELRTLFLFEKLDDEQLAWLCREGRVEYFEPGPVYREGEEATCFYVLMDGEVVLSKLSAGEDLELVRTDHRGSYAGAWTAYMGERADRNYTGSLTVTKPSKFFVLGADTFAQMMQEWFPMALHLLEGVFFGNRNTNEIIGRRERLLALGSLSAGLTHELNNPAAAAVRATSSLRDRVAGMRHKLKMMAHGKFDSATLESLVQLQEEAATQVAKAPTLTPLEAADREDELGDWLDDHGIDGGWDLAPNFVQAGFDIDWMERVSATLGECDRGVFEGAIRWLNYTVETELLMNEITDSTGRISSLVHAAKQYSQMDRAPFQVVDIHELLDSTLVMLARKIGDHITVIKEYDHTLPEVPCYAAELNQVWTNLIDNAVAAMSGTGTLSIRTYRENDCAAVEIGDTGPGVPEALRDRIFEPFFTTKPVGEGTGLGLDISFRIVVNKHGGDIRVESQPGDTRFIVRLPLTAPGRGADAES
>NZ_CP006850.1|WP_025353187.1|7776403_7778077_-|FAD-dependent-oxidoreductase
MTSPAAVKPVILSVDDDPGVSRAVVRDLRRRYGADYRTMRADSGDSALEVLRELKLRGQPVAVLIADYRMPGMDGIQFLEHAIDLHPYARRVLLTAYADTNAAIDAINVVDLDHYLLKPWDPPEEKLYPVVDALLESWRGDDRRPVHETKIIGHRWSARGSEVREFLARNQLPYRWYLADDPEGQRLLEAAGADAEQCPVVIDPSGDVLLSPSDSELAECVGLSTDPSGEFYDLIVIGGGPAGLGAAVYGASEGLRTVLVERTATGGQAGQSSRIENYLGFPDGLSGAQLADRARRQAVKFGAELITAREVVGLEVCGSARRVLFADGSCVSAHSVLIATGVNYRHHPAPGVDDFTGRGVYYGSAMTEAADCADRDVYIVGGANSAGQAAVFLSRQAGSVHILVRGASLEQSMSHYLIQQIEAVPNIKVHTNTEVVAADGSDHLERIVLRNNATGAEEKVAAERLFLFIGAAPETDWLAGLLVRDDAGYLLAGPDLVIDGARPAGWELPRAPHHLETSIPGVFVAGDVRSESAKRVASAVGEGAMAVMLVHRYLAKQ

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Crispr_ID: NZ_CP006850_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006850_18

8134682-8134776

Orphan

Consensus_repeat	Method
GCCGGGAGCGACGGGGCCGGAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006850_18

>merge|NZ_CP006850|18|8134682-8134776|CRISPRCasFinder
GCCGGGAGCGACGGGGCCGGAGGCGGCAGCCTGCGTAACCACGAAGGCCCCCGCGTACGGCGCGAAGATTCGGCCGCGAGCGACGGGGCCGGAGG

>NZ_CP006850|18|18|8134682-8134776|CRISPRCasFinder
GCCGGGAGCGACGGGGCCGGAGG	CGGCAGCCTGCGTAACCACGAAGGCCCCCGCGTACGGCGCGAAGATTCG
GCCGCGAGCGACGGGGCCGGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006850.1\|WP_038551344.1\|8131640_8132741_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_038556048.1\|8124700_8125894_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NZ_CP006850.1\|WP_025353469.1\|8127943_8129776_-\|phosphoenolpyruvate-carboxykinase-(GTP)	unknown	unknown	gnl\|CDD\|235256
NZ_CP006850.1\|WP_148307093.1\|8140997_8141378_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025353466.1\|8126193_8126994_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|369777
NZ_CP006850.1\|WP_025353472.1\|8133175_8134531_+\|lipase	unknown	unknown	gnl\|CDD\|367570
NZ_CP006850.1\|WP_025353467.1\|8127014_8127299_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_193365224.1\|8145645_8147115_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
NZ_CP006850.1\|WP_025353480.1\|8144126_8145299_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|279875
NZ_CP006850.1\|WP_038556051.1\|8127498_8127693_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_051494893.1\|8142958_8144125_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|226951
NZ_CP006850.1\|WP_025353478.1\|8142290_8142962_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP006850.1\|WP_025353477.1\|8141518_8142232_-\|DUF1707-domain-containing-protein	unknown	unknown	gnl\|CDD\|377959
NZ_CP006850.1\|WP_025353470.1\|8130052_8131600_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006850.1\|WP_025353464.1\|8123874_8124531_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224001
NZ_CP006850.1\|WP_025353473.1\|8135511_8136258_+\|NYN-domain-containing-protein	unknown	unknown	gnl\|CDD\|376672
NZ_CP006850.1\|WP_025353474.1\|8136257_8140481_+\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|225272
NZ_CP006850.1\|WP_025353462.1\|8121996_8123292_-\|glycosyltransferase-family-1-protein	unknown	unknown	gnl\|CDD\|340817
NZ_CP006850.1\|WP_025353475.1\|8140531_8140912_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319924
NZ_CP006850.1\|WP_081769590.1\|8147210_8148305_+\|UPF0104-family-protein	unknown	unknown	gnl\|CDD\|223469

Protein	Function_ID	Function_description	E-value
NZ_CP006850.1\|WP_038556048.1\|8124700_8125894_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	4.95055e-54
NZ_CP006850.1\|WP_025353469.1\|8127943_8129776_-\|phosphoenolpyruvate-carboxykinase-(GTP)	gnl\|CDD\|235256	PRK04210, PRK04210, phosphoenolpyruvate carboxykinase (GTP).	0
NZ_CP006850.1\|WP_025353477.1\|8141518_8142232_-\|DUF1707-domain-containing-protein	gnl\|CDD\|377959	pfam08044, DUF1707, Domain of unknown function (DUF1707). This domain is found in a variety of Actinomycetales proteins. All of the proteins containing this domain are hypothetical and probably membrane bound or associated. Currently, it is unclear to the function of this domain.	2.02202e-20
NZ_CP006850.1\|WP_025353466.1\|8126193_8126994_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.36404e-17
NZ_CP006850.1\|WP_025353472.1\|8133175_8134531_+\|lipase	gnl\|CDD\|367570	pfam03583, LIP, Secretory lipase. These lipases are expressed and secreted during the infection cycle of these pathogens. In particular, C. albicans has a large number of different lipases, possibly reflecting broad lipolytic activity, which may contribute to the persistence and virulence of C. albicans in human tissue.	2.93838e-68
NZ_CP006850.1\|WP_193365224.1\|8145645_8147115_+\|HAMP-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	1.09535e-48
NZ_CP006850.1\|WP_025353480.1\|8144126_8145299_-\|AI-2E-family-transporter	gnl\|CDD\|279875	pfam01594, AI-2E_transport, AI-2E family transporter. This family includes four different proteins from E. coli alone. One of them, YdgG or TqsA, has been shown to mediate transport of the quorum-sensing signal autoinducer 2 (AI-2). It is not clear if TqsA enhances secretion of AI-2 or inhibits AI-2 uptake. By altering the intracellular concentration of AI-2, TqsA affects gene expression in biofilms and biofilm formation. TsqA belongs to the AI-2 exporter (AI-2E) superfamily.	1.48139e-53
NZ_CP006850.1\|WP_051494893.1\|8142958_8144125_-\|ATP-binding-protein	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.09461e-15
NZ_CP006850.1\|WP_025353478.1\|8142290_8142962_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.36351e-60
NZ_CP006850.1\|WP_081769590.1\|8147210_8148305_+\|UPF0104-family-protein	gnl\|CDD\|223469	COG0392, COG0392, Predicted integral membrane protein [Function unknown].	7.85945e-24
NZ_CP006850.1\|WP_025353464.1\|8123874_8124531_+\|hypothetical-protein	gnl\|CDD\|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	2.23161e-05
NZ_CP006850.1\|WP_025353473.1\|8135511_8136258_+\|NYN-domain-containing-protein	gnl\|CDD\|376672	pfam01936, NYN, NYN domain. These domains are found in the eukaryotic proteins typified by the Nedd4-binding protein 1 and the bacterial YacP-like proteins (Nedd4-BP1, YacP nucleases; NYN domains). The NYN domain shares a common protein fold with two other previously characterized groups of nucleases, namely the PIN (PilT N-terminal) and FLAP/5' --> 3' exonuclease superfamilies. These proteins share a common set of 4 acidic conserved residues that are predicted to constitute their active site. Based on the conservation of the acidic residues and structural elements Aravind and colleagues suggest that PIN and NYN domains are likely to bind only a single metal ion, unlike the FLAP/5' --> 3' exonuclease superfamily, which binds two metal ions. Based on conserved gene neighborhoods Aravind and colleagues infer that the bacterial members are likely to be components of the processome/degradsome that process tRNAs or ribosomal RNAs.	0.000179799
NZ_CP006850.1\|WP_025353474.1\|8136257_8140481_+\|MMPL-family-transporter	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	4.05609e-136
NZ_CP006850.1\|WP_025353462.1\|8121996_8123292_-\|glycosyltransferase-family-1-protein	gnl\|CDD\|340817	cd03784, GT1_Gtf-like, UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.	2.00422e-56
NZ_CP006850.1\|WP_025353475.1\|8140531_8140912_+\|hypothetical-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	6.6865e-16

>NZ_CP006850.1|WP_025353472.1|8133175_8134531_+|lipase
MSVSVDVIGRGGGSATTETKPERLLPPSRDPFYRAPANLASHAPGTVLRSRPVQIALLGVIPQRVSAWQLLCRSTDLHGRPEAVVTTVLLPGDGDPMAPRPLLAFQSAIDAATERCIPSYALRRGAFVPGSITQLEWVLVAGALRRGWAVSIADHEGMHGRFGAPREPGYRGLDGVRAALHFPPLGLASDTPVVVWGYSGGGMAGSWMVEMAPTYAPELRIVGAALGAPVGDPGEVFLRLNGGPYAGFPAIVIAALRQAYPALAEVIDGRIDAAGERLLERALRLPPIVALARLAGQDVGRYLDRPLDEVLDGPAMRAMFDDMRLGQHVPECPVLIIQPVHDQIIHTSCVDGQVQRYRRGGATVDYVRDRLSEHFSLLPLATPMSLDWLADRLAGVPVTETGTRTVWSVVADPGRWRGLLDMAGTAGRVLLGLPLGRQSEPRLPEARPLAA
>NZ_CP006850.1|WP_038551344.1|8131640_8132741_-|hypothetical-protein
MNDHGGSTALELDQLVATVRVGADPRIADQLSAAVACYRRPLRIQVAGRAGAGRTTLLRALALMSAEETAPVDEPGAPDPVLDADLVIYALAGSLQPADRRILESLRAESTLVVLNKADAVGSRWGDAVNAAEQATHGLGVPVAPVVAELAVRTRSGTPAEEDLRTLRRHAAGSGTALTLSPELFVDESAGLDVAERRAVLERWGLYGVSCALVALRHEPDLGPQQLLQVLHAASGIDPVHVGLHDRYEQIGALRGSELLDELARIAARAVPRDDGGRARDLIEDYLVGEEALWIGVRAGLAVPEVRHLAAGYPAAMPRDADDALLRAQRWRAVAASDMPAVARRAAIRLHNGYMRMWERMSSAGL
>NZ_CP006850.1|WP_025353470.1|8130052_8131600_-|hypothetical-protein
MPGDAGGSALADDVLAVVERWNPAGATLLRSVPPAGPGAGWPETAHGLAHGVDNSVVLVGPDDPNTTLLRTELSRFEPRLALGDPIADPANLMDMPGSAPAVVLVLLDPGTAAGAALVDPVAGLHASGARILFAMNGVHAHPGWRSTLERDAATLARALGVAPEIVPVSARLAVASRGDGDPALLDRSGLAALHTQLSAAIGNHGPDRLAGATARVLADTRTRILGQIEALSSGTGVARLRAERTTALAGRDGGRAQALAALRNRLQLARVDLTHEVGARIRTLNATARADLERLDRRGVRDYPERLQQLVNQSTAELDVFVGGRLAELARQIEAVTGPAPGPWQAPGPHGPADPPPRVGSDPDGRPRGVEDRLMIALGASAGFGLGRLIVAPLSLVPALDIATVPITLALGAGVAWWVVRARGHLADRAHLRQWVTDALVNVKAQLEQRVATALVEAESDLTDRVVRASTARMVETDHRVAELEGQLRRAVAEQPAQLAACQRDLAILDAAAES
>NZ_CP006850.1|WP_025353469.1|8127943_8129776_-|phosphoenolpyruvate-carboxykinase-(GTP)
MTSATIPGLHGSDGTAPTEHAGLLAWVQEVAELTQPDRVVWADGSDAEWDRLTTALVEAGTFQKLNEHKKPNSFLALSDPSDVARVESRTYICSRTEADAGPTNNWVDPAEMRATMTELYRGSMKGRTMYVVPFCMGPLGAEDPKLGVEITDSEYVVVSMRVMTRMGKAALEKLGKDRPFVKALHSVGAPLAEGQADVPWPCNDTKYITHFPEDREIWSYGSGYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPEGKNHYVAAAFPSACGKTNLAMLQPTVPGWRAETLGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNHNSNPNAMATLEAGNTVYTNVALTDDHDVWWEGLEGEPDHLIDWKGNDWTLRETETLAAHPNSRYCTPMSQCPTLAPEWDDPQGVPISAILFGGRRKTTIPLVTESFDWQHGVFMGATMSSEQTAAAEGKVGNVRRDPMAMLPFMGYHVGDYMNHWINLGKNADAAKLPKIFYVNWFRRGDDGRFLWPGFGENSRVLEWIINRIEGKAEAESTAVGNVPTASQLDLEGLDVDPADVDASLKVDLDEWRKEIPLIEEWFEFVGDKLPSGIRDEFEALKQRLG
>NZ_CP006850.1|WP_038556051.1|8127498_8127693_-|hypothetical-protein
MTGLEFDPAEVSGFVVAAASTPLARAAARLQAVLPPGWRVDIDVATPRPQDDPQPVLRVRMSEN
>NZ_CP006850.1|WP_025353467.1|8127014_8127299_-|hypothetical-protein
MAVQVVGRSLMTSDQTPHQARSVGTGGWVVSFLPGRTLTLEQATAALQAAEVVATVRSLANRVGLTPLETVGLAMQEPPWNEPPRPSRRRGWLE
>NZ_CP006850.1|WP_025353466.1|8126193_8126994_+|methyltransferase-domain-containing-protein
MLRSDATGPRPRFARRATLRRSLRLLSSFRFEQTDPGRFYGGIADDTADLVADFYRDLTGRDLTGTTVIDVGGGPGYFAERFAAAGARYIPIEPDPAEMHAAGLTVAGAVRGSGMALPIRDDAVDICLSSNVAEHVPDPWLMADEMLRITKPGGLMVLSYTIWLGPFGGHETGPWHYLGGEYAARRYLRRTGQQPKNRFGTSLFAVTTADGLHWAREAEGRARILATFPRYHPRWAWWVTRVPGVRELLVSNLVVVATKPNRTHTS
>NZ_CP006850.1|WP_038556048.1|8124700_8125894_-|glycosyltransferase-family-4-protein
MSAPGDPVREVLLLCWRDTGHPQGGGSERYLERVGAQLAARGVKVTLRTARYRGAARRERIDGIEISRAGGRFSVYPRALAAIAAGRMGFGPLRGLRPDAVIDTQNGIPFFARVVSGAPSVVLVHHGHREQWPVAGRLVGRIGWWIESWLSPRVHRNDQYLTVSLPSAEELASLGVDAARIAVVRNGAEPVPGQSPTGAEPIRTPHPSIVVLSRLVPHKQIEDALEVVAGLRGRLPGLELDVIGDGWWADNLKTRARELGIADAVNFHGFVDEPRKHELLSRAWVQVLPSRKEGWGLAVIEAAQHGVPTIGYRSSRGLTDSIVDGVTGVLVDDVFQLTETTGELLADPEMRVVMGEKARTRAREFSWEQTGFGVGSVVAAAARGEFVSGLVAGRSAE
>NZ_CP006850.1|WP_025353464.1|8123874_8124531_+|hypothetical-protein
MLSALHDAGYCALLFQGGVVSDKRWAGDIPASAQQLSDFVAKVRQRTGAKKVDIVAHSASTVVSNYFLKVLHGAPEISHAVFLAPEARGCDGAGFLADYGIHNPPITPVEVLQAIPFLATMLTAASPDLAAAIQMTPQSQVYHAIFDGPITQPGVHYSVLSTRHDEVATPPTTCSVISEPGVTMNFYDDLFPDAPAVGHSDLRSSANTTGWVVQQLNT
>NZ_CP006850.1|WP_025353462.1|8121996_8123292_-|glycosyltransferase-family-1-protein
MKVSVLTYGSRGDFQPHLAVAGELRERGHEVVMAVNKNNLAAVEGAGITPVKIPVDIRTFLASPAAQQFLYPNGILDIRGKLGFARKLARLEAGRDSYVNEALITACEGADIIVTGALVFARAQSIVERSGQPLVGCIPYPIERSREFSSPHVWHRPLPTPLLRGASHLMFEQVYRRATHAGLRRLRRRLGLSDEVPNPFSRLRERETPMDLLVSPVIFPKPSDWPDRCTVGGTPKLAAAERAAWGEQTDPGLESWLSDGEPPILFSLGSIPVEDPEGYLSMITEVTARSGARALVAAGYTDFPLGPRADGRVLVTGPLDYDAILPRCRAAVHAGGPGTTHDVARAGIPSVATPVFGDQLLWGWRLAAAGIGVDIVYRKLTAQRLADALQRIDDPGMRARAAAAGEVIAQEDGARHMCDIIERQAVVRRAG
>NZ_CP006850.1|WP_025353473.1|8135511_8136258_+|NYN-domain-containing-protein
MSPRETAPTADEVAATVHGSESDPVTGASAPVADSTGVRRVLLVWDAPNLDMGLGAILGGRPTAAYRPRFDALGRWLLARTAELSAGSTQRIEPEATVFTNIAPGTADVVRPWVEALRNVGYAVFAKPKIDEDSDVDSDMLAHIQLRRSGAGLAGIMVASADGQAFREPLEEVASTGVPVQVLGFREHASWAVTSDILDFVDLEDIPGVFREPLPRVSLDSLPDEGAWLQPFRPLSALLTSRPAQGVA
>NZ_CP006850.1|WP_025353474.1|8136257_8140481_+|MMPL-family-transporter
MFTRWGELVHKFRYTVLGVAVAALLALGAYGFGLDNHLSSSGWFDPGAESSQAAVLKDQVYGRDHLSDVITLYTAPEGKTIDDPEFGQKITENLNSLPKEHPDQISKVNVSYWKTETGDWSQSTTGSKDKKYAFATIAIKGDDDTTMVNNYRAVKDAFYIPGVDVQVAGLQPVAGTLNDTIASDQQRMEILAIPLVGILLFFIFGGVVAAALPLIIGGLTVLGARGIVMAITNVTEVNSFVGAVVSMIGLGLAIDYGLFIVSRFREEMAEGYTTRQAVRRSVMTAGRTVVFSATMIIAASAGMLIFPQGFLKSVAYGTIATVLLAAVASLTILPAMLSILGKRVDALGLKRFRKTRTAEEVENGFWGRTTQWVMKHPLKVAVPLCIILLLLIIPVKNLKFGGISETYLPPDNPTRVAQEKFDSIFPLRQTDPVQLVITTDNTSEIKPLLDDASNAPGLAHEFGTPGIPPNNSNVWVSETTLAPDANIEDTLAYLRTVPVPDDVQLLVGGQPVLMQDSITSLLDRMPLMIIVVVLVTTLLMFLTFGSLVLPIKAALMSALGLGSTLGILTWIFVDGHGAGLLNFTPQPIMSPVLVLIMAIIYGLSTDYEVFLLSRMVEARAQGASTTEAVRSGTAQTGRIITAAALILLVVVGAFAFSDLVMMQYIAYGMMAALFIDATVLRMLLVPATMKLLGDDCWWAPAWMKRVQQRVGLGEPILDDERPGSGDVVDLVKTTPVTDPVTMQLPQMPDGTVKGPKKPRRLKFLRVDPEAPTEQLTRIDPDMPPPSDAPGKPRRATHPEPETPDTDSPDESPADAAPSETPKRKRRIFRRAGADADVPVADSGAGQSATEPGDPAAPAPADDAGDRSTPSASGSVPSRPTSPPQTSGKGAARVLPPERSNPVDANGVIGAVEASGVIGPAEHGADERGGLLGIQDTYGPGATGTPGSAPSSPTFRPPEANGAGASDARGGFGPAAAMRAAGPAEPLRPEPPRPDTTRPQPPRTDIGRSEGPRPETSRPDVPRPETSRADTARPEGARPGASRPETSRAGTAWPETSPADATRADAARPDTSHADTAWHEASRPDATGPETVRPEFRSGGPRPDTARPDARSGGPRPDTTWPDATSGGPRPDTTRPDARSGGPRPDTTRPNAPRPDAPRPGPRPDAPHPDTPRGEVRPDTTRPAEPPAGRYSGPPAVSMPGTDPTQNRGVNQPPQVVRPGMPPRTVPVSEAPTEATDPVPPAEPSGTTPRVLPPKPSKLPPHPSVRAQLYRPDAPPYHPGPGAEPDPGPTGRTPADAAPQQADPSPWVAPENHVPSVQLPRRVPADQAPAAPPENRPVDDGTSTPAAESNAGPGDDNRNDIEQWMADLRSSRRRPESEETPEDPEDPKHRNSGRTVSVNELLRRQNRD
>NZ_CP006850.1|WP_025353475.1|8140531_8140912_+|hypothetical-protein
MSAPTFTSVLTVAVPVSDQDRTKTLLEGLGFETHLDTELQPGFRWVELRMPGAGTSLSLVATGDALPAGIDTGVRLGTPDARAAHTALAARGLDVGELLDWPTAPLMFSFLDPDGNRFYVTQDFAE
>NZ_CP006850.1|WP_148307093.1|8140997_8141378_-|hypothetical-protein
MSLEFSRLGRLKRMFSRALSTMGRALAVTAVPLAAVAVFAGAASADAGQSAATPVVAQSISGIPLEDVTTDPGAQYPDPVMNGAAAGAAIGSATGSFIDPFPTLLGAVIGGAVGQQRPDLVPQVLP
>NZ_CP006850.1|WP_025353477.1|8141518_8142232_-|DUF1707-domain-containing-protein
MGGETVSTPGVGSVPPAGGAVGDRDLRVSDAEREHVGGLLQRAVGLGMLSLGEFSERMDTALAAKTRGELNAVLVDLPGIRLAGQPNPVPAAGPPNGRAWTPAASRWGSQSSDSGTVTLRPRLSGLTRKGPWQVPAVIEINSFLSGTTLDFTQAVMSTQVVEIRVDDFCSSLNLILPGAATVDLNGVELIGSSTNNKVRTGPPIGPLHIVVHGRIRFSSINAKHPFGVQWKKLVSGF
>NZ_CP006850.1|WP_025353478.1|8142290_8142962_-|response-regulator-transcription-factor
MTDNRAETTAEISVMVVDDHPMWRDGVSRDLAEAGFRVAATADGVGAAGRRAAAVRPDVVLMDMQLPDGNGAQATAEVLRVSPHSRVLVLSASGERDDVLEAIKAGATGYLVKSASVAELIDAVRATAAGQAVFTPGLAGVVLGEFRRIAGAPADTGAERPVLTERETEVLRLVAKGLSAKQIATRLGVSHRTVENHVQATLRKLQLGNRVELTRYAIEQGLE
>NZ_CP006850.1|WP_051494893.1|8142958_8144125_-|ATP-binding-protein
MSAAADTRVAATAPLWRAAQVFRLVTMVYAVGQQFVSVSSYRNPALSWVLIAVLAVWSVVSALWLSRWSLTDSGRRAVVIGDLAVSVGLMAATRLVADQPWYHGHQTLPTTLWVANAVMSAAIEWGALGGVLSALLISVVSIVVREQWELDLWSDATAPVLVSVGLAIGLAAGTARRAQGQLEEAMRLRAATAERERLAREVHDGVLQVLSYIKRRGGEIGGDTADLARRAGEQEVALRVLISEQGRRESADGRGSDEDLRSLVNAFAAPTVFVSAPGEPVSLGGWTAREIAAAVGAALSNTALHAGSDAKAYVLLEDMGDAVVVSVRDDGPGIPSGRLSAAVAEGRLGVAQSIIGRIEALGGTAELLDTTDGTEWEFRIPLDREERR
>NZ_CP006850.1|WP_025353480.1|8144126_8145299_-|AI-2E-family-transporter
MHPLVRQSAEWCWRLLIILVAVLALAYLAHKLTTVVIPVAIALLGAALLSPLVDLLQRLGMPRGIGVFVALVGSIGLLAGIFTFVIEQFVSGVPQLTDEFKTSIHTVQDWLINGPLHLSDEQIRNAGNTIIKTIEANQDSLTSGALTTAAAIGEFLTGTFLTMFILIFFLYGGDQIWHFATRIVPTPQRERVRTAGRLGFGTLIGFVRATVVVAAVDAIGIGAGLAILSVPLALPLASLVFIGAFIPIIGSLLAGSVAVFLALMTKGFVTALIVLGVTIAVMQLESHVLQPLLLGRAVRIHPLAVVLAITAGVVLAGIAGGLLAVPFVAVMNTAIRSLLSGSPEELYQELSSGDPGEPMFHAEADKLDPDRYRPHEPPGEGSAGGVPSAG
>NZ_CP006850.1|WP_193365224.1|8145645_8147115_+|HAMP-domain-containing-protein
MRTRWPLYLASMLAANAFGAVLVYAFIQYGLPSPEGTPNGVRRAGLLLPGLVFVIGGLLSVTASALMLRPVMRWQVRGGPPSRQEQMAALHAPLRQSILHLMLWLVGGAVLAARIIVDTPELAGAVIVTECMAATIVFGFTYMLGERILRPVAAHALTTGTFDHTLTPGVGTRMAMTWGMGTFAPTIAIVLLCVTQITSQVHFSAQSLAISILLLCGVVIMQALALSMLTGSSISDPVRQLSRAINRVQAGAHDVQVEVFDGSEIGLLQVGFNRMMEEAAQRRELQELFGQHVGEDVARRALEYGTELGGETRFVAVLFVDMVGSTATAAERPPTEVVSLLNEFFRVVVDVVDRHNGLINKFVGDAALAIFGAPLDRPDAPTAALAAARDLRVALREVPGLDIGIGVSAGLAVAGNIGAANRFEYTVIGDPVNEASRLTELAKEYPGRVLASGSALYFADDDEQRQWTSGDEVQLRGRRRKTRLAWPKT
>NZ_CP006850.1|WP_081769590.1|8147210_8148305_+|UPF0104-family-protein
MKWVLGVALLALLIGEGVYLWPRLHDSWRSLTEIHWGWVALCILMQAVSMSGFGRIQKRLLHAGGVDVTQRASVSVVYGATAMSVSLPAGQVFSTAFTYRQTRRWGASPVVASWQLLMSGVIATAGMLLLGVGGAFLVGNRVGPWKLVLTLGAVALLVWAGKYISGNPGALQALIRRGVRLFNRVRRHPPEADMDRVDDALRQLESVDLGRRDAAWVAFWAVVHRLGDVACLGAACYAIGADPRWAGLLIAFSVGKAVGTIPFAPGGIVYVDATLVASLTAAAGLQFSQAIAAAAVYRLVSFILVAIVGWIVVAFRFRNPQAGDAEFEQEFEQHRSALLTEPRRADQPGEESPGPAEPNGEAPA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP006850_12	12.1\|6101645\|25\|NZ_CP006850\|CRISPRCasFinder	6101645-6101669	25	NZ_CP032314	Pannonibacter phragmitetus BB plasmid p.BB_2, complete sequence	1423-1447	4	0.84
NZ_CP006850_6	6.1\|1907393\|28\|NZ_CP006850\|CRISPRCasFinder	1907393-1907420	28	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1299359-1299386	5	0.821
NZ_CP006850_12	12.1\|6101645\|25\|NZ_CP006850\|CRISPRCasFinder	6101645-6101669	25	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	139966-139990	5	0.8
NZ_CP006850_6	6.1\|1907393\|28\|NZ_CP006850\|CRISPRCasFinder	1907393-1907420	28	NZ_LR723678	Arsenite-oxidising bacterium NT-25 plasmid 2	192136-192163	6	0.786
NZ_CP006850_6	6.1\|1907393\|28\|NZ_CP006850\|CRISPRCasFinder	1907393-1907420	28	NZ_FO082821	Rhizobium sp. NT-26 plasmid NT26_p1, complete sequence	273357-273384	6	0.786
NZ_CP006850_6	6.1\|1907393\|28\|NZ_CP006850\|CRISPRCasFinder	1907393-1907420	28	NZ_CP010872	Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6003, complete sequence	5669-5696	6	0.786
NZ_CP006850_6	6.1\|1907393\|28\|NZ_CP006850\|CRISPRCasFinder	1907393-1907420	28	NZ_CP031599	Roseovarius indicus strain DSM 26383 plasmid pRIdsm_01, complete sequence	343673-343700	6	0.786
NZ_CP006850_6	6.1\|1907393\|28\|NZ_CP006850\|CRISPRCasFinder	1907393-1907420	28	NZ_CP012662	Defluviimonas alba strain cai42 plasmid pcai42A, complete sequence	83316-83343	6	0.786
NZ_CP006850_6	6.1\|1907393\|28\|NZ_CP006850\|CRISPRCasFinder	1907393-1907420	28	NZ_AP022339	Mameliella alba strain KU6B plasmid pKUB112, complete sequence	8588-8615	6	0.786
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010612	Phaeobacter inhibens strain P92 plasmid pP92_b, complete sequence	77808-77839	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010624	Phaeobacter inhibens strain P51 plasmid pP51_a, complete sequence	77823-77854	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010669	Phaeobacter inhibens strain P57 plasmid pP57_a, complete sequence	77823-77854	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP031957	Phaeobacter sp. LSS9 plasmid unnamed1, complete sequence	166108-166139	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NC_018291	Phaeobacter inhibens DSM 17395 plasmid pPGA1_262, complete sequence	76647-76678	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010596	Phaeobacter inhibens strain P10 plasmid pP10_a, complete sequence	77804-77835	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010682	Phaeobacter piscinae strain P14 plasmid pP14_a, complete sequence	76498-76529	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010630	Phaeobacter inhibens strain P78 plasmid pP78_a, complete sequence	178280-178311	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010717	Phaeobacter piscinae strain P18 plasmid pP18_b, complete sequence	77922-77953	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP031953	Phaeobacter inhibens strain 2.10 plasmid unnamed1, complete sequence	76812-76843	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NC_018421	Phaeobacter inhibens 2.10 plasmid pPGA2_239, complete sequence	76719-76750	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010657	Phaeobacter piscinae strain P71 plasmid pP71_a, complete sequence	76527-76558	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP031949	Phaeobacter inhibens strain BS107 plasmid unnamed1, complete sequence	76648-76679	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010618	Phaeobacter inhibens strain P30 isolate M4-3.1A plasmid pP30_a, complete sequence	77015-77046	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010726	Phaeobacter inhibens strain P88 plasmid pP88_a, complete sequence	77809-77840	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010768	Phaeobacter piscinae strain P13 plasmid pP13_a, complete sequence	76508-76539	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010651	Phaeobacter inhibens strain P54 plasmid pP54_a, complete sequence	77809-77840	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010644	Phaeobacter piscinae strain P36 plasmid pP36_a, complete sequence	76548-76579	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010697	Phaeobacter inhibens strain P24 plasmid pP24_a, complete sequence	77823-77854	6	0.812
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP010736	Phaeobacter inhibens strain P72 plasmid pP72_a, complete sequence	77823-77854	6	0.812
NZ_CP006850_9	9.5\|1926525\|33\|NZ_CP006850\|CRISPRCasFinder,CRT,PILER-CR	1926525-1926557	33	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	753557-753589	6	0.818
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010612	Phaeobacter inhibens strain P92 plasmid pP92_b, complete sequence	77808-77840	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010624	Phaeobacter inhibens strain P51 plasmid pP51_a, complete sequence	77823-77855	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010669	Phaeobacter inhibens strain P57 plasmid pP57_a, complete sequence	77823-77855	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP031957	Phaeobacter sp. LSS9 plasmid unnamed1, complete sequence	166107-166139	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NC_018291	Phaeobacter inhibens DSM 17395 plasmid pPGA1_262, complete sequence	76647-76679	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010596	Phaeobacter inhibens strain P10 plasmid pP10_a, complete sequence	77804-77836	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010682	Phaeobacter piscinae strain P14 plasmid pP14_a, complete sequence	76498-76530	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010630	Phaeobacter inhibens strain P78 plasmid pP78_a, complete sequence	178279-178311	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010717	Phaeobacter piscinae strain P18 plasmid pP18_b, complete sequence	77922-77954	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP031953	Phaeobacter inhibens strain 2.10 plasmid unnamed1, complete sequence	76812-76844	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NC_018421	Phaeobacter inhibens 2.10 plasmid pPGA2_239, complete sequence	76719-76751	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010657	Phaeobacter piscinae strain P71 plasmid pP71_a, complete sequence	76527-76559	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP031949	Phaeobacter inhibens strain BS107 plasmid unnamed1, complete sequence	76648-76680	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010618	Phaeobacter inhibens strain P30 isolate M4-3.1A plasmid pP30_a, complete sequence	77015-77047	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010726	Phaeobacter inhibens strain P88 plasmid pP88_a, complete sequence	77809-77841	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010768	Phaeobacter piscinae strain P13 plasmid pP13_a, complete sequence	76508-76540	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010651	Phaeobacter inhibens strain P54 plasmid pP54_a, complete sequence	77809-77841	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010644	Phaeobacter piscinae strain P36 plasmid pP36_a, complete sequence	76548-76580	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010697	Phaeobacter inhibens strain P24 plasmid pP24_a, complete sequence	77823-77855	7	0.788
NZ_CP006850_8	8.2\|1923798\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923798-1923830	33	NZ_CP010736	Phaeobacter inhibens strain P72 plasmid pP72_a, complete sequence	77823-77855	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KX783441	Klebsiella pneumoniae strain KP4368 plasmid pKP4368, complete sequence	14448-14480	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP015071	Escherichia coli strain Ecol_743 plasmid pEC743_OXA48, complete sequence	24833-24865	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KM406488	Salmonella enterica subsp. enterica serovar Paratyphi B strain R69 plasmid R69, complete sequence	31648-31680	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KP975075	Citrobacter freundii strain MRSN12115 plasmid pMRVIM1012, complete sequence	38229-38261	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP029447	Serratia marcescens strain CAV1761 plasmid pCAV1761-73, complete sequence	71069-71101	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP031566	Enterobacter hormaechei strain 2013_1a plasmid pIncLM-1301491, complete sequence	2404-2436	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP019841	Enterobacter roggenkampii strain R11 plasmid pASM2, complete sequence	7456-7488	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP010365	Enterobacter hormaechei subsp. oharae strain 34978 plasmid p34978-70.092kb, complete sequence	9421-9453	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018669	Klebsiella pneumoniae strain CAV1042 plasmid pKPC_CAV1042-89, complete sequence	4405-4437	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018452	Klebsiella pneumoniae strain Kp_Goe_71070 plasmid pKp_Goe_070-2, complete sequence	44455-44487	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP016927	Klebsiella pneumoniae isolate 23 plasmid pIncL_M_DHQP1400954, complete sequence	11087-11119	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP027148	Klebsiella pneumoniae strain AR_0363 plasmid unnamed5	43383-43415	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	MN187903	Citrobacter freundii strain Cf164 plasmid pCf164_CTX-M-8, complete sequence	31578-31610	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP032170	Klebsiella pneumoniae strain AR_0076 plasmid unnamed3, complete sequence	36933-36965	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	CP020502	Serratia marcescens strain BWH-23 plasmid unnamed, complete sequence	13519-13551	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP029720	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed2, complete sequence	39926-39958	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP021742	Klebsiella pneumoniae strain AR_0126 plasmid tig00000002jNODE_23, complete sequence	38837-38869	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KY781949	Klebsiella pneumoniae isolate Kp41 plasmid pKp41M, complete sequence	51680-51712	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP014072	Klebsiella quasipneumoniae strain FDAARGOS_93 plasmid unnamed1	4049-4081	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP050846	Klebsiella pneumoniae strain Bckp206 plasmid pBckp206-1, complete sequence	1066-1098	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KT935445	Klebsiella pneumoniae strain Kp6411 plasmid 6411TF, complete sequence	59441-59473	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KP025948	Proteus mirabilis strain Pm-Oxa48 plasmid pOXA48-Pm, complete sequence	53267-53299	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP011599	Phytobacter ursingii strain CAV1151 plasmid pCAV1151-83, complete sequence	13083-13115	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP037737	Citrobacter freundii strain CAV1857 plasmid pKPC_CAV1857-85, complete sequence	51223-51255	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP020530	Enterobacter cloacae strain 174 plasmid unnamed2, complete sequence	61672-61704	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_005246	Erwinia amylovora LebB66 plasmid pEL60, complete sequence	32629-32661	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP029138	Klebsiella pneumoniae strain AR376 plasmid unnamed3, complete sequence	54479-54511	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP029599	Klebsiella quasipneumoniae subsp. similipneumoniae strain ATCC 700603 plasmid pDA33145-77, complete sequence	2262-2294	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP022826	Klebsiella quasivariicola strain KPN1705 plasmid pKPN1705-3, complete sequence	48509-48541	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_AP019667	Klebsiella pneumoniae strain TA6363 plasmid pTMTA63632, complete sequence	69566-69598	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP011614	Klebsiella oxytoca strain CAV1335 plasmid pCAV1335-92, complete sequence	85623-85655	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP017932	Klebsiella oxytoca strain CAV1015 plasmid pCAV1015-76, complete sequence	220-252	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP017936	Klebsiella pneumoniae strain CAV1016 plasmid pCAV1016-76, complete sequence	15185-15217	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP011640	Serratia marcescens strain CAV1492 plasmid pCAV1492-73, complete sequence	61121-61153	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP045017	Klebsiella pneumoniae subsp. pneumoniae strain BK13048 plasmid pBK13048-2, complete sequence	39404-39436	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP011632	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-84, complete sequence	13401-13433	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP014698	Klebsiella quasipneumoniae strain ATCC 700603 isolate K6 plasmid pKQPS2, complete sequence	42668-42700	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP011593	Klebsiella oxytoca strain CAV1099 plasmid pCAV1099-69, complete sequence	26947-26979	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP011656	Citrobacter freundii strain CAV1741 plasmid pKPC_CAV1741, complete sequence	96544-96576	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP011609	Citrobacter freundii strain CAV1321 plasmid pCAV1321-71, complete sequence	61472-61504	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_019346	Enterobacter cloacae plasmid pNE1280, complete sequence	3968-4000	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP027699	Klebsiella pneumoniae strain KP30835 plasmid unnamed4, complete sequence	64256-64288	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LT985279	Escherichia coli strain 676 plasmid RCS60_p, complete sequence	36409-36441	7	0.788
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018449	Klebsiella pneumoniae strain Kp_Goe_33208 plasmid pKp_Goe_208-2, complete sequence	46048-46080	7	0.788
NZ_CP006850_8	8.7\|1923860\|33\|NZ_CP006850\|PILER-CR	1923860-1923892	33	NZ_CP044989	Deinococcus sp. AJ005 plasmid p380k, complete sequence	372191-372223	7	0.788
NZ_CP006850_8	8.7\|1923860\|33\|NZ_CP006850\|PILER-CR	1923860-1923892	33	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	105352-105384	7	0.788
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KY781949	Klebsiella pneumoniae isolate Kp41 plasmid pKp41M, complete sequence	51681-51712	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP014072	Klebsiella quasipneumoniae strain FDAARGOS_93 plasmid unnamed1	4050-4081	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP050846	Klebsiella pneumoniae strain Bckp206 plasmid pBckp206-1, complete sequence	1067-1098	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KX783441	Klebsiella pneumoniae strain KP4368 plasmid pKP4368, complete sequence	14448-14479	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KT935445	Klebsiella pneumoniae strain Kp6411 plasmid 6411TF, complete sequence	59442-59473	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP015071	Escherichia coli strain Ecol_743 plasmid pEC743_OXA48, complete sequence	24833-24864	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KM406488	Salmonella enterica subsp. enterica serovar Paratyphi B strain R69 plasmid R69, complete sequence	31648-31679	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KP025948	Proteus mirabilis strain Pm-Oxa48 plasmid pOXA48-Pm, complete sequence	53268-53299	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KP975075	Citrobacter freundii strain MRSN12115 plasmid pMRVIM1012, complete sequence	38229-38260	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP011599	Phytobacter ursingii strain CAV1151 plasmid pCAV1151-83, complete sequence	13084-13115	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP016593	Ketogulonicigenium vulgare strain SKV plasmid pKvSKV1, complete sequence	222511-222542	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_017386	Ketogulonicigenium vulgare WSH-001 plasmid 1, complete sequence	157712-157743	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP037737	Citrobacter freundii strain CAV1857 plasmid pKPC_CAV1857-85, complete sequence	51224-51255	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_014621	Ketogulonicigenium vulgare Y25 plasmid pYP1, complete sequence	124574-124605	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP029447	Serratia marcescens strain CAV1761 plasmid pCAV1761-73, complete sequence	71069-71100	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP012909	Ketogulonicigenium vulgare strain Hbe602 plasmid 1, complete sequence	222521-222552	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP020530	Enterobacter cloacae strain 174 plasmid unnamed2, complete sequence	61673-61704	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP031566	Enterobacter hormaechei strain 2013_1a plasmid pIncLM-1301491, complete sequence	2404-2435	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_005246	Erwinia amylovora LebB66 plasmid pEL60, complete sequence	32630-32661	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP029138	Klebsiella pneumoniae strain AR376 plasmid unnamed3, complete sequence	54480-54511	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP019841	Enterobacter roggenkampii strain R11 plasmid pASM2, complete sequence	7456-7487	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP010365	Enterobacter hormaechei subsp. oharae strain 34978 plasmid p34978-70.092kb, complete sequence	9421-9452	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP029599	Klebsiella quasipneumoniae subsp. similipneumoniae strain ATCC 700603 plasmid pDA33145-77, complete sequence	2263-2294	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP022826	Klebsiella quasivariicola strain KPN1705 plasmid pKPN1705-3, complete sequence	48510-48541	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_AP019667	Klebsiella pneumoniae strain TA6363 plasmid pTMTA63632, complete sequence	69567-69598	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP011614	Klebsiella oxytoca strain CAV1335 plasmid pCAV1335-92, complete sequence	85624-85655	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP017932	Klebsiella oxytoca strain CAV1015 plasmid pCAV1015-76, complete sequence	221-252	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP017936	Klebsiella pneumoniae strain CAV1016 plasmid pCAV1016-76, complete sequence	15186-15217	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018669	Klebsiella pneumoniae strain CAV1042 plasmid pKPC_CAV1042-89, complete sequence	4405-4436	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018452	Klebsiella pneumoniae strain Kp_Goe_71070 plasmid pKp_Goe_070-2, complete sequence	44455-44486	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP011640	Serratia marcescens strain CAV1492 plasmid pCAV1492-73, complete sequence	61122-61153	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP045017	Klebsiella pneumoniae subsp. pneumoniae strain BK13048 plasmid pBK13048-2, complete sequence	39405-39436	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP011632	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-84, complete sequence	13402-13433	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP016927	Klebsiella pneumoniae isolate 23 plasmid pIncL_M_DHQP1400954, complete sequence	11087-11118	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP027148	Klebsiella pneumoniae strain AR_0363 plasmid unnamed5	43383-43414	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP014698	Klebsiella quasipneumoniae strain ATCC 700603 isolate K6 plasmid pKQPS2, complete sequence	42669-42700	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP011593	Klebsiella oxytoca strain CAV1099 plasmid pCAV1099-69, complete sequence	26948-26979	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP011656	Citrobacter freundii strain CAV1741 plasmid pKPC_CAV1741, complete sequence	96545-96576	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP011609	Citrobacter freundii strain CAV1321 plasmid pCAV1321-71, complete sequence	61473-61504	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	MN187903	Citrobacter freundii strain Cf164 plasmid pCf164_CTX-M-8, complete sequence	31578-31609	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP032170	Klebsiella pneumoniae strain AR_0076 plasmid unnamed3, complete sequence	36933-36964	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	CP020502	Serratia marcescens strain BWH-23 plasmid unnamed, complete sequence	13519-13550	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_019346	Enterobacter cloacae plasmid pNE1280, complete sequence	3969-4000	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP029720	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed2, complete sequence	39926-39957	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP027699	Klebsiella pneumoniae strain KP30835 plasmid unnamed4, complete sequence	64257-64288	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LT985279	Escherichia coli strain 676 plasmid RCS60_p, complete sequence	36410-36441	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP021742	Klebsiella pneumoniae strain AR_0126 plasmid tig00000002jNODE_23, complete sequence	38837-38868	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018449	Klebsiella pneumoniae strain Kp_Goe_33208 plasmid pKp_Goe_208-2, complete sequence	46049-46080	7	0.781
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	334721-334752	7	0.781
NZ_CP006850_9	9.1\|1926283\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1926283-1926315	33	NZ_CP039632	Pseudomonas veronii strain Pvy plasmid unnamed, complete sequence	95318-95350	7	0.788
NZ_CP006850_9	9.1\|1926283\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1926283-1926315	33	NZ_CP007510	Pseudomonas stutzeri strain 19SMN4 plasmid pLIB119, complete plasmid	81169-81201	7	0.788
NZ_CP006850_9	9.1\|1926283\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1926283-1926315	33	NZ_AP015030	Pseudomonas putida strain KF715 plasmid pKF715A, complete sequence	51579-51611	7	0.788
NZ_CP006850_9	9.4\|1926466\|31\|NZ_CP006850\|CRISPRCasFinder,CRT,PILER-CR	1926466-1926496	31	MH651189	Gordonia phage Schmidt, complete genome	2536-2566	7	0.774
NZ_CP006850_9	9.6\|1926586\|33\|NZ_CP006850\|CRISPRCasFinder,CRT,PILER-CR	1926586-1926618	33	NZ_CP012886	Mycobacterium chimaera strain AH16 plasmid unnamed1, complete sequence	17109-17141	7	0.788
NZ_CP006850_8	8.3\|1923859\|34\|NZ_CP006850\|CRISPRCasFinder,CRT	1923859-1923892	34	NZ_CP044989	Deinococcus sp. AJ005 plasmid p380k, complete sequence	372190-372223	8	0.765
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KM406490	Salmonella enterica subsp. enterica serovar Typhimurium strain 202 plasmid pSEM, complete sequence	24838-24870	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KM406489	Serratia marcescens strain R471 plasmid R471, complete sequence	81550-81582	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	CP048042	Serratia liquefaciens strain JL02 plasmid unnamed1, complete sequence	2517-2549	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP016593	Ketogulonicigenium vulgare strain SKV plasmid pKvSKV1, complete sequence	222511-222543	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_017386	Ketogulonicigenium vulgare WSH-001 plasmid 1, complete sequence	157712-157744	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP034202	Klebsiella pneumoniae subsp. pneumoniae strain KpvST383_NDM_OXA-48 plasmid pKpvST383L_2, complete sequence	18841-18873	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP035217	Klebsiella michiganensis strain M82255 plasmid pKOCBH-C, complete sequence	74377-74409	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_014621	Ketogulonicigenium vulgare Y25 plasmid pYP1, complete sequence	124574-124606	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP012909	Ketogulonicigenium vulgare strain Hbe602 plasmid 1, complete sequence	222521-222553	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018717	Klebsiella pneumoniae strain Kp_Goe_152021 plasmid pKp_Goe_021-3, complete sequence	54046-54078	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018723	Klebsiella pneumoniae strain KP_Goe_828304 plasmid pKp_Goe_304-3, complete sequence	51151-51183	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018706	Klebsiella pneumoniae strain Kp_Goe_827024 plasmid pKp_Goe_024-3, complete sequence	4143-4175	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC556214	Escherichia coli CEX24 plasmid pCEX24 DNA, complete sequence	24300-24332	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC556215	Escherichia coli CEX25 plasmid pCEX25 DNA, complete sequence	24300-24332	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC556216	Escherichia coli CEX14 plasmid pCEX14 DNA, complete sequence	24300-24332	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC556217	Escherichia coli CEX3 plasmid pCEX3 DNA, complete sequence	24300-24332	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC556218	Enterobacter cloacae CEX5 plasmid pCEX5 DNA, complete sequence	24300-24332	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC556219	Enterobacter cloacae CEX6 plasmid pCEX6 DNA, complete sequence	24300-24332	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC556220	Enterobacter cloacae CEX4 plasmid pCEX4 DNA, complete sequence	24300-24332	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC556221	Klebsiella pneumoniae CEX18 plasmid pCEX18 DNA, complete sequence	24300-24332	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC556222	Klebsiella pneumoniae CEX23 plasmid pCEX23 DNA, complete sequence	24300-24332	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_024997	Klebsiella oxytoca plasmid pACM1, complete sequence	60988-61020	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP034325	Klebsiella pneumoniae isolate KSH203 plasmid pKSH203-CTX-M-3, complete sequence	57964-57996	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_025134	Klebsiella pneumoniae plasmid pFOX-7a, complete sequence	26697-26729	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP017853	Klebsiella variicola strain GJ2 plasmid pKPGJ-2d, complete sequence	51077-51109	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP009852	UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH4 plasmid pENT-e56, complete sequence	63193-63225	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP026395	Klebsiella pneumoniae strain KPNIH48 plasmid pKPC-edb7, complete sequence	54306-54338	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP026142	Klebsiella pneumoniae strain F127 plasmid pF127_2, complete sequence	32067-32099	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP026210	Citrobacter sp. CFNIH10 plasmid pKPC-2fe2, complete sequence	74653-74685	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018315	Klebsiella pneumoniae strain Kp_Goe_822579 plasmid pKp_Goe_579-3, complete sequence	10204-10236	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP015075	Escherichia coli strain Ecol_745 plasmid pEC745_OXA48, complete sequence	49593-49625	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	KU159086	Klebsiella pneumoniae plasmid pOXAAPSS2, complete sequence	21041-21073	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018690	Klebsiella pneumoniae strain Kp_Goe_149473 plasmid pKp_Goe_473-3, complete sequence	52638-52670	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP031374	Klebsiella pneumoniae strain KpvST101_OXA-48 plasmid pKpvOXA-48, complete sequence	40431-40463	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP032193	Salmonella enterica subsp. enterica serovar Senftenberg strain AR_0127 plasmid unnamed2, complete sequence	62852-62884	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018342	Klebsiella pneumoniae isolate Kp_Goe_154414 plasmid pKp_Goe_414-5, complete sequence	4149-4181	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP033880	Escherichia coli strain 50579417 plasmid p50579417_3_OXA-48, complete sequence	110-142	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP042490	Enterobacter hormaechei strain C15 plasmid pC15_002	21220-21252	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018712	Klebsiella pneumoniae strain Kp_Goe_827026 plasmid pKp_Goe_026-3, complete sequence	57264-57296	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KY215945	Klebsiella pneumoniae subsp. pneumoniae strain Kp1210 plasmid pOXA-519, complete sequence	35848-35880	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KY213890	Klebsiella pneumoniae strain 38_wz plasmid pOXA48_wz, complete sequence	37781-37813	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LT838202	Escherichia coli isolate WI2 isolate plasmid pWI2-OXA48, complete sequence	35505-35537	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LN864821	Raoultella planticola plasmid pRA35, complete sequence, strain RA35	38599-38631	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KX523901	Klebsiella pneumoniae strain Kpn-30715/15 plasmid pOXA-48_30715, complete sequence	40518-40550	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KX523900	Klebsiella pneumoniae strain Kpn-04963/15 plasmid pOXA-48_4963, complete sequence	38596-38628	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KX523902	Klebsiella pneumoniae strain Kpn-30891/15 plasmid pOXA-48_30891, complete sequence	41089-41121	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KX636096	Klebsiella pneumoniae strain RJ119 plasmid pRJ119-2, complete sequence	4428-4460	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KX009507	Escherichia coli strain 06K2206 plasmid LM6771, complete sequence	77296-77328	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_019368	Enterobacter cloacae plasmid pEl1573, complete sequence	32524-32556	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KM406491	Klebsiella pneumoniae strain Kpn-E1.Nr7 plasmid pKpn-E1.Nr7, complete sequence	12850-12882	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KP659188	Klebsiella pneumoniae strain 153877-1 plasmid pOXA-48E1, complete sequence	42955-42987	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KP061858	Enterobacter cloacae strain INSRA17313-1 plasmid pUR17313-1, complete sequence	35909-35941	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KM877517	Enterobacter cloacae strain CRE623 plasmid pIMP-HB623, complete sequence	114413-114445	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KP294351	Escherichia coli strain CZD1527 plasmid pIGT15, complete sequence	55751-55783	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_KU315015	Serratia marcescens strain NCTC 50331 plasmid R1215, complete sequence	77088-77120	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	AP018454	Klebsiella pneumoniae plasmid pMRY13-133KPN_2 DNA, complete genome, strain: MRY13-133	60149-60181	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	AP018455	Klebsiella aerogenes plasmid pMRY13-134EAE_1 DNA, complete genome, strain: MRY13-134	68033-68065	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP034041	Klebsiella pneumoniae subsp. pneumoniae strain CRK0298 plasmid p2, complete sequence	45717-45749	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP026156	Klebsiella pneumoniae strain B12(AN) plasmid pB12AN_1, complete sequence	39501-39533	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP044032	Klebsiella pneumoniae strain FDAARGOS_631 plasmid unnamed1, complete sequence	41713-41745	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP048353	Raoultella ornithinolytica strain 23 plasmid p23_D-OXA48, complete sequence	44104-44136	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP034283	Klebsiella pneumoniae strain I72 plasmid p72_LM_OXA48, complete sequence	44104-44136	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_004464	Citrobacter freundii plasmid pCTX-M3, complete sequence	35582-35614	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP023419	Klebsiella pneumoniae strain 1050 plasmid pKp1050-3, complete sequence	51429-51461	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP042501	Enterobacter sp. E76 plasmid pE76_002, complete sequence	77200-77232	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP048339	Escherichia coli strain 142 plasmid p142_B, complete sequence	39752-39784	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	MK249855	Enterobacter cloacae strain 105 plasmid unnamed, complete sequence	37054-37086	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	MK249856	Klebsiella pneumoniae strain 91 plasmid unnamed, complete sequence	37054-37086	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	MK249858	Escherichia coli strain 46 plasmid unnamed, complete sequence	37054-37086	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP042509	Leclercia adecarboxylata strain E1 plasmid pE1_004, complete sequence	62669-62701	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_021488	Klebsiella pneumoniae plasmid pKPoxa-48N1, complete sequence	5861-5893	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_021502	Klebsiella pneumoniae plasmid pKPoxa-48N2, complete sequence	5861-5893	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP026194	Enterobacteriaceae bacterium ENNIH1 plasmid pKPC-825d, complete sequence	63117-63149	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP027039	Klebsiella pneumoniae strain 16_GR_13 plasmid IncLM, complete sequence	12913-12945	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP020844	Klebsiella pneumoniae strain KPN1482 plasmid pKPN1482-3, complete sequence	40359-40391	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_019154	Klebsiella pneumoniae plasmid pOXA-48, complete sequence	37054-37086	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP041085	Klebsiella pneumoniae strain Kp202 plasmid pKp202_3, complete sequence	44104-44136	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP023251	Klebsiella pneumoniae strain CCUG 70742 plasmid pKpn70742_2	12977-13009	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LT994838	Klebsiella variicola isolate CNR130 plasmid CNR130, complete sequence	22870-22902	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	MK966141	Enterobacter cloacae strain GHZ8R11B plasmid pHNGDR11, complete sequence	35949-35981	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	MK966142	Klebsiella pneumoniae strain GHP8R3B plasmid pHNGDR03, complete sequence	34556-34588	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP024878	Klebsiella pneumoniae strain NH25 plasmid pNH25.4, complete sequence	64779-64811	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP042514	Serratia marcescens strain E28 plasmid pE28_002, complete sequence	68390-68422	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LT985387	Escherichia coli strain 694 genome assembly, plasmid: RCS55_pI	39631-39663	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP031805	Klebsiella pneumoniae strain MSB1_8A-sc-2280397 plasmid unnamed5, complete sequence	46014-46046	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP045511	Salmonella enterica subsp. enterica serovar Anatum strain M-5360 plasmid p55k, complete sequence	35611-35643	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC508263	Klebsiella pneumoniae A1-3 plasmid pA1-3 DNA, complete sequence	32311-32343	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP007733	Klebsiella pneumoniae subsp. pneumoniae KPNIH27 plasmid pKPN-068, complete sequence	75301-75333	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP040036	Klebsiella pneumoniae strain KPC160117 plasmid pOXA48-L117, complete sequence	46014-46046	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP022153	Citrobacter freundii strain 705SK3 plasmid p705SK3_2, complete sequence	44120-44152	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP017288	Klebsiella variicola strain GJ3 plasmid pKPGJ-3d, complete sequence	18368-18400	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_019063	Escherichia coli plasmid pNDM-HK, complete sequence	69730-69762	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP022150	Enterobacter roggenkampii strain 704SK10 plasmid p704SK10_2, complete sequence	44120-44152	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	MG516907	Klebsiella aerogenes plasmid pEa1631, complete sequence	32524-32556	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LR025105	Escherichia coli isolate EC-1639 plasmid pOXA-48_1639, complete sequence	44104-44136	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP009857	UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-d0d, complete sequence	55031-55063	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP042532	Klebsiella aerogenes strain C9 plasmid pC9_002, complete sequence	68390-68422	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP026385	Serratia sp. SSNIH1 plasmid pKPC-56ce, complete sequence	28218-28250	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP017282	Klebsiella variicola strain GJ1 plasmid pKPGJ-1c, complete sequence	14757-14789	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LT994833	Klebsiella pneumoniae isolate CNR341 plasmid CNR341, complete sequence	22033-22065	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP031235	Escherichia coli strain Es_ST410_NW1_NDM_09_2017 plasmid pEsST410_NW_NDM, complete sequence	12153-12185	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	KP294350	Uncultured bacterium plasmid pARM26, complete sequence	67860-67892	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	MN792918	Klebsiella aerogenes strain ST143 plasmid pLAU_KAM9_OXA48, complete sequence	16643-16675	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018974	Escherichia coli strain Ecol_545 plasmid pEC545_KPC, complete sequence	21396-21428	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP040031	Klebsiella pneumoniae strain KPC160121 plasmid pOXA48-L121, complete sequence	46014-46046	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018461	Klebsiella pneumoniae strain Kp_Goe_39795 plasmid pKp_Goe_795-2, complete sequence	18129-18161	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP032174	Klebsiella pneumoniae strain AR_0160 plasmid unnamed2, complete sequence	49756-49788	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC536683	Klebsiella pneumoniae MyNCGM084 plasmid pMyNCGM084, complete sequence	61184-61216	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP048418	Citrobacter freundii strain CitB plasmid pB_CitB, complete sequence	37082-37114	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LR025095	Klebsiella pneumoniae isolate KP9201 plasmid pOXA-48_920, complete sequence	44107-44139	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC545849	Escherichia coli Ec-MW04 plasmid pEc-MW04_OXA DNA, complete sequence	49481-49513	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP042574	Enterobacter hormaechei strain E5 plasmid pE5_003, complete sequence	67063-67095	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP042542	Enterobacter hormaechei strain C4 plasmid pC4_002, complete sequence	68390-68422	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP014298	Klebsiella pneumoniae strain KP38731 plasmid unnamed2, complete sequence	35481-35513	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP042580	Enterobacter kobei strain C16 plasmid pC16_002, complete sequence	62669-62701	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	KU159085	Klebsiella pneumoniae plasmid pOXAAPSS1, complete sequence	33804-33836	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_023027	Klebsiella pneumoniae strain E71T plasmid, complete sequence	39070-39102	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP026497	Klebsiella pneumoniae strain 616 plasmid pKp616_2, complete sequence	35757-35789	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP026188	Enterobacteriaceae bacterium ENNIH2 plasmid pKPC-ddab, complete sequence	64784-64816	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP044337	Enterobacter hormaechei strain AKB48 plasmid unnamed2, complete sequence	5058-5090	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LN864819	Klebsiella pneumoniae plasmid pKP112, complete sequence, strain KP112	59282-59314	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP031216	Escherichia coli strain Es_ST80_L1_NDM_10_2017 plasmid pEsST80_L1_NDM, complete sequence	19100-19132	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LR025091	Klebsiella pneumoniae isolate KP980 plasmid pOXA-48_980, complete sequence	44104-44136	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP038457	Escherichia coli strain EC-129 plasmid pEC129_4, complete sequence	39022-39054	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_011641	Klebsiella pneumoniae plasmid pCTXM360, complete sequence	5862-5894	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_019344	Serratia marcescens plasmid R830b, complete sequence	48465-48497	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP042526	Citrobacter freundii strain E11 plasmid pE11_002, complete sequence	68390-68422	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP031322	Escherichia coli strain ST2350 isolate Es_ST2350_SE1_NDM_03_2018 plasmid pEsST2350_SE_NDM, complete sequence	72243-72275	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	CP052472	Klebsiella pneumoniae strain C16KP0053 plasmid pC16KP0053-4, complete sequence	39096-39128	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018700	Klebsiella pneumoniae strain Kp_Goe_149832 plasmid pKp_Goe_832-3, complete sequence	59333-59365	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LR745044	Klebsiella pneumoniae isolate Klebsiella pneumoniae kpn154 plasmid pOXA48_Kpn154	36881-36913	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_021078	Klebsiella pneumoniae strain Kp002 plasmid pJEG011, complete sequence	46476-46508	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LT985264	Escherichia coli strain 717 plasmid RCS51TR717_p, complete sequence	60218-60250	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_LT985241	Escherichia coli strain 721 plasmid RCS40_p, complete sequence	62074-62106	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC505604	Klebsiella pneumoniae A1-1 plasmid pKp1-1 genomic DNA, complete sequence	32311-32343	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	LC508722	Klebsiella pneumoniae A2-1 plasmid pA2-4 DNA, complete sequence	32311-32343	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NC_019889	Klebsiella pneumoniae strain 601 plasmid pNDM-OM, complete sequence	18384-18416	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	MT193824	Escherichia coli strain 19-AB01443 plasmid pOX-48-EC1443, complete sequence	12832-12864	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_MK088079	Klebsiella pneumoniae strain 19 plasmid unnamed, complete sequence	17109-17141	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_MK370728	Klebsiella pneumoniae strain 69G1 plasmid pLimOXA-48, complete sequence	43338-43370	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP030135	Klebsiella pneumoniae strain 160111 plasmid pOXA48_L111, complete sequence	12953-12985	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP042568	Enterobacter hormaechei strain C44 plasmid pC44_002, complete sequence	68390-68422	8	0.758
NZ_CP006850_8	8.4\|1923921\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923921-1923953	33	NZ_CP018736	Klebsiella pneumoniae strain Kp_Goe_121641 plasmid pKp_Goe_641-2	46581-46613	8	0.758
NZ_CP006850_8	8.7\|1923860\|33\|NZ_CP006850\|PILER-CR	1923860-1923892	33	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	568453-568485	8	0.758
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KY215945	Klebsiella pneumoniae subsp. pneumoniae strain Kp1210 plasmid pOXA-519, complete sequence	35849-35880	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KY213890	Klebsiella pneumoniae strain 38_wz plasmid pOXA48_wz, complete sequence	37782-37813	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LT838202	Escherichia coli isolate WI2 isolate plasmid pWI2-OXA48, complete sequence	35506-35537	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LN864821	Raoultella planticola plasmid pRA35, complete sequence, strain RA35	38600-38631	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KX523901	Klebsiella pneumoniae strain Kpn-30715/15 plasmid pOXA-48_30715, complete sequence	40519-40550	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KX523900	Klebsiella pneumoniae strain Kpn-04963/15 plasmid pOXA-48_4963, complete sequence	38597-38628	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KX523902	Klebsiella pneumoniae strain Kpn-30891/15 plasmid pOXA-48_30891, complete sequence	41090-41121	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KX636096	Klebsiella pneumoniae strain RJ119 plasmid pRJ119-2, complete sequence	4429-4460	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KX009507	Escherichia coli strain 06K2206 plasmid LM6771, complete sequence	77297-77328	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_019368	Enterobacter cloacae plasmid pEl1573, complete sequence	32525-32556	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KM406491	Klebsiella pneumoniae strain Kpn-E1.Nr7 plasmid pKpn-E1.Nr7, complete sequence	12851-12882	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KP659188	Klebsiella pneumoniae strain 153877-1 plasmid pOXA-48E1, complete sequence	42956-42987	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KM406490	Salmonella enterica subsp. enterica serovar Typhimurium strain 202 plasmid pSEM, complete sequence	24838-24869	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KM406489	Serratia marcescens strain R471 plasmid R471, complete sequence	81550-81581	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KP061858	Enterobacter cloacae strain INSRA17313-1 plasmid pUR17313-1, complete sequence	35910-35941	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KM877517	Enterobacter cloacae strain CRE623 plasmid pIMP-HB623, complete sequence	114414-114445	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KP294351	Escherichia coli strain CZD1527 plasmid pIGT15, complete sequence	55752-55783	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_KU315015	Serratia marcescens strain NCTC 50331 plasmid R1215, complete sequence	77089-77120	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	AP018454	Klebsiella pneumoniae plasmid pMRY13-133KPN_2 DNA, complete genome, strain: MRY13-133	60150-60181	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	AP018455	Klebsiella aerogenes plasmid pMRY13-134EAE_1 DNA, complete genome, strain: MRY13-134	68034-68065	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	CP048042	Serratia liquefaciens strain JL02 plasmid unnamed1, complete sequence	2517-2548	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP034041	Klebsiella pneumoniae subsp. pneumoniae strain CRK0298 plasmid p2, complete sequence	45718-45749	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP026156	Klebsiella pneumoniae strain B12(AN) plasmid pB12AN_1, complete sequence	39502-39533	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP044032	Klebsiella pneumoniae strain FDAARGOS_631 plasmid unnamed1, complete sequence	41714-41745	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP048353	Raoultella ornithinolytica strain 23 plasmid p23_D-OXA48, complete sequence	44105-44136	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP034283	Klebsiella pneumoniae strain I72 plasmid p72_LM_OXA48, complete sequence	44105-44136	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_004464	Citrobacter freundii plasmid pCTX-M3, complete sequence	35583-35614	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP034202	Klebsiella pneumoniae subsp. pneumoniae strain KpvST383_NDM_OXA-48 plasmid pKpvST383L_2, complete sequence	18841-18872	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP023419	Klebsiella pneumoniae strain 1050 plasmid pKp1050-3, complete sequence	51430-51461	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP035217	Klebsiella michiganensis strain M82255 plasmid pKOCBH-C, complete sequence	74377-74408	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP042501	Enterobacter sp. E76 plasmid pE76_002, complete sequence	77201-77232	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP048339	Escherichia coli strain 142 plasmid p142_B, complete sequence	39753-39784	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	MK249855	Enterobacter cloacae strain 105 plasmid unnamed, complete sequence	37055-37086	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	MK249856	Klebsiella pneumoniae strain 91 plasmid unnamed, complete sequence	37055-37086	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	MK249858	Escherichia coli strain 46 plasmid unnamed, complete sequence	37055-37086	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP042509	Leclercia adecarboxylata strain E1 plasmid pE1_004, complete sequence	62670-62701	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018717	Klebsiella pneumoniae strain Kp_Goe_152021 plasmid pKp_Goe_021-3, complete sequence	54046-54077	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018723	Klebsiella pneumoniae strain KP_Goe_828304 plasmid pKp_Goe_304-3, complete sequence	51151-51182	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018706	Klebsiella pneumoniae strain Kp_Goe_827024 plasmid pKp_Goe_024-3, complete sequence	4143-4174	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_021488	Klebsiella pneumoniae plasmid pKPoxa-48N1, complete sequence	5862-5893	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_021502	Klebsiella pneumoniae plasmid pKPoxa-48N2, complete sequence	5862-5893	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP026194	Enterobacteriaceae bacterium ENNIH1 plasmid pKPC-825d, complete sequence	63118-63149	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP027039	Klebsiella pneumoniae strain 16_GR_13 plasmid IncLM, complete sequence	12914-12945	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC556214	Escherichia coli CEX24 plasmid pCEX24 DNA, complete sequence	24300-24331	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC556215	Escherichia coli CEX25 plasmid pCEX25 DNA, complete sequence	24300-24331	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC556216	Escherichia coli CEX14 plasmid pCEX14 DNA, complete sequence	24300-24331	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC556217	Escherichia coli CEX3 plasmid pCEX3 DNA, complete sequence	24300-24331	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC556218	Enterobacter cloacae CEX5 plasmid pCEX5 DNA, complete sequence	24300-24331	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC556219	Enterobacter cloacae CEX6 plasmid pCEX6 DNA, complete sequence	24300-24331	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC556220	Enterobacter cloacae CEX4 plasmid pCEX4 DNA, complete sequence	24300-24331	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC556221	Klebsiella pneumoniae CEX18 plasmid pCEX18 DNA, complete sequence	24300-24331	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC556222	Klebsiella pneumoniae CEX23 plasmid pCEX23 DNA, complete sequence	24300-24331	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP020844	Klebsiella pneumoniae strain KPN1482 plasmid pKPN1482-3, complete sequence	40360-40391	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_019154	Klebsiella pneumoniae plasmid pOXA-48, complete sequence	37055-37086	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_024997	Klebsiella oxytoca plasmid pACM1, complete sequence	60988-61019	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP041085	Klebsiella pneumoniae strain Kp202 plasmid pKp202_3, complete sequence	44105-44136	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP023251	Klebsiella pneumoniae strain CCUG 70742 plasmid pKpn70742_2	12978-13009	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LT994838	Klebsiella variicola isolate CNR130 plasmid CNR130, complete sequence	22871-22902	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	MK966141	Enterobacter cloacae strain GHZ8R11B plasmid pHNGDR11, complete sequence	35950-35981	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	MK966142	Klebsiella pneumoniae strain GHP8R3B plasmid pHNGDR03, complete sequence	34557-34588	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP024878	Klebsiella pneumoniae strain NH25 plasmid pNH25.4, complete sequence	64780-64811	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP034325	Klebsiella pneumoniae isolate KSH203 plasmid pKSH203-CTX-M-3, complete sequence	57964-57995	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_025134	Klebsiella pneumoniae plasmid pFOX-7a, complete sequence	26697-26728	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP042514	Serratia marcescens strain E28 plasmid pE28_002, complete sequence	68391-68422	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LT985387	Escherichia coli strain 694 genome assembly, plasmid: RCS55_pI	39632-39663	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP031805	Klebsiella pneumoniae strain MSB1_8A-sc-2280397 plasmid unnamed5, complete sequence	46015-46046	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP045511	Salmonella enterica subsp. enterica serovar Anatum strain M-5360 plasmid p55k, complete sequence	35612-35643	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC508263	Klebsiella pneumoniae A1-3 plasmid pA1-3 DNA, complete sequence	32312-32343	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP007733	Klebsiella pneumoniae subsp. pneumoniae KPNIH27 plasmid pKPN-068, complete sequence	75302-75333	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP040036	Klebsiella pneumoniae strain KPC160117 plasmid pOXA48-L117, complete sequence	46015-46046	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP022153	Citrobacter freundii strain 705SK3 plasmid p705SK3_2, complete sequence	44121-44152	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP017288	Klebsiella variicola strain GJ3 plasmid pKPGJ-3d, complete sequence	18369-18400	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_019063	Escherichia coli plasmid pNDM-HK, complete sequence	69731-69762	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP022150	Enterobacter roggenkampii strain 704SK10 plasmid p704SK10_2, complete sequence	44121-44152	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	MG516907	Klebsiella aerogenes plasmid pEa1631, complete sequence	32525-32556	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP017853	Klebsiella variicola strain GJ2 plasmid pKPGJ-2d, complete sequence	51077-51108	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LR025105	Escherichia coli isolate EC-1639 plasmid pOXA-48_1639, complete sequence	44105-44136	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP009852	UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH4 plasmid pENT-e56, complete sequence	63193-63224	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP009857	UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-d0d, complete sequence	55032-55063	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP042532	Klebsiella aerogenes strain C9 plasmid pC9_002, complete sequence	68391-68422	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP026385	Serratia sp. SSNIH1 plasmid pKPC-56ce, complete sequence	28219-28250	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP026395	Klebsiella pneumoniae strain KPNIH48 plasmid pKPC-edb7, complete sequence	54306-54337	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP017282	Klebsiella variicola strain GJ1 plasmid pKPGJ-1c, complete sequence	14758-14789	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LT994833	Klebsiella pneumoniae isolate CNR341 plasmid CNR341, complete sequence	22034-22065	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP031235	Escherichia coli strain Es_ST410_NW1_NDM_09_2017 plasmid pEsST410_NW_NDM, complete sequence	12154-12185	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	KP294350	Uncultured bacterium plasmid pARM26, complete sequence	67861-67892	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	MN792918	Klebsiella aerogenes strain ST143 plasmid pLAU_KAM9_OXA48, complete sequence	16644-16675	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018974	Escherichia coli strain Ecol_545 plasmid pEC545_KPC, complete sequence	21397-21428	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP026142	Klebsiella pneumoniae strain F127 plasmid pF127_2, complete sequence	32067-32098	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP040031	Klebsiella pneumoniae strain KPC160121 plasmid pOXA48-L121, complete sequence	46015-46046	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018461	Klebsiella pneumoniae strain Kp_Goe_39795 plasmid pKp_Goe_795-2, complete sequence	18130-18161	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP032174	Klebsiella pneumoniae strain AR_0160 plasmid unnamed2, complete sequence	49757-49788	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC536683	Klebsiella pneumoniae MyNCGM084 plasmid pMyNCGM084, complete sequence	61185-61216	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP048418	Citrobacter freundii strain CitB plasmid pB_CitB, complete sequence	37083-37114	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LR025095	Klebsiella pneumoniae isolate KP9201 plasmid pOXA-48_920, complete sequence	44108-44139	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP026210	Citrobacter sp. CFNIH10 plasmid pKPC-2fe2, complete sequence	74653-74684	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC545849	Escherichia coli Ec-MW04 plasmid pEc-MW04_OXA DNA, complete sequence	49482-49513	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP042574	Enterobacter hormaechei strain E5 plasmid pE5_003, complete sequence	67064-67095	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP042542	Enterobacter hormaechei strain C4 plasmid pC4_002, complete sequence	68391-68422	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018315	Klebsiella pneumoniae strain Kp_Goe_822579 plasmid pKp_Goe_579-3, complete sequence	10204-10235	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP015075	Escherichia coli strain Ecol_745 plasmid pEC745_OXA48, complete sequence	49593-49624	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP014298	Klebsiella pneumoniae strain KP38731 plasmid unnamed2, complete sequence	35482-35513	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP042580	Enterobacter kobei strain C16 plasmid pC16_002, complete sequence	62670-62701	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	KU159085	Klebsiella pneumoniae plasmid pOXAAPSS1, complete sequence	33805-33836	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	KU159086	Klebsiella pneumoniae plasmid pOXAAPSS2, complete sequence	21041-21072	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018690	Klebsiella pneumoniae strain Kp_Goe_149473 plasmid pKp_Goe_473-3, complete sequence	52638-52669	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP031374	Klebsiella pneumoniae strain KpvST101_OXA-48 plasmid pKpvOXA-48, complete sequence	40431-40462	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP032193	Salmonella enterica subsp. enterica serovar Senftenberg strain AR_0127 plasmid unnamed2, complete sequence	62852-62883	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_023027	Klebsiella pneumoniae strain E71T plasmid, complete sequence	39071-39102	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP026497	Klebsiella pneumoniae strain 616 plasmid pKp616_2, complete sequence	35758-35789	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP026188	Enterobacteriaceae bacterium ENNIH2 plasmid pKPC-ddab, complete sequence	64785-64816	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP044337	Enterobacter hormaechei strain AKB48 plasmid unnamed2, complete sequence	5059-5090	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LN864819	Klebsiella pneumoniae plasmid pKP112, complete sequence, strain KP112	59283-59314	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018342	Klebsiella pneumoniae isolate Kp_Goe_154414 plasmid pKp_Goe_414-5, complete sequence	4149-4180	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP031216	Escherichia coli strain Es_ST80_L1_NDM_10_2017 plasmid pEsST80_L1_NDM, complete sequence	19101-19132	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LR025091	Klebsiella pneumoniae isolate KP980 plasmid pOXA-48_980, complete sequence	44105-44136	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP038457	Escherichia coli strain EC-129 plasmid pEC129_4, complete sequence	39023-39054	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_011641	Klebsiella pneumoniae plasmid pCTXM360, complete sequence	5863-5894	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_019344	Serratia marcescens plasmid R830b, complete sequence	48466-48497	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP042526	Citrobacter freundii strain E11 plasmid pE11_002, complete sequence	68391-68422	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP033880	Escherichia coli strain 50579417 plasmid p50579417_3_OXA-48, complete sequence	110-141	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP031322	Escherichia coli strain ST2350 isolate Es_ST2350_SE1_NDM_03_2018 plasmid pEsST2350_SE_NDM, complete sequence	72244-72275	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	CP052472	Klebsiella pneumoniae strain C16KP0053 plasmid pC16KP0053-4, complete sequence	39097-39128	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018700	Klebsiella pneumoniae strain Kp_Goe_149832 plasmid pKp_Goe_832-3, complete sequence	59334-59365	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LR745044	Klebsiella pneumoniae isolate Klebsiella pneumoniae kpn154 plasmid pOXA48_Kpn154	36882-36913	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_021078	Klebsiella pneumoniae strain Kp002 plasmid pJEG011, complete sequence	46477-46508	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP042490	Enterobacter hormaechei strain C15 plasmid pC15_002	21220-21251	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LT985264	Escherichia coli strain 717 plasmid RCS51TR717_p, complete sequence	60219-60250	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_LT985241	Escherichia coli strain 721 plasmid RCS40_p, complete sequence	62075-62106	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018712	Klebsiella pneumoniae strain Kp_Goe_827026 plasmid pKp_Goe_026-3, complete sequence	57264-57295	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC505604	Klebsiella pneumoniae A1-1 plasmid pKp1-1 genomic DNA, complete sequence	32312-32343	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	LC508722	Klebsiella pneumoniae A2-1 plasmid pA2-4 DNA, complete sequence	32312-32343	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_019889	Klebsiella pneumoniae strain 601 plasmid pNDM-OM, complete sequence	18385-18416	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	MT193824	Escherichia coli strain 19-AB01443 plasmid pOX-48-EC1443, complete sequence	12833-12864	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_MK088079	Klebsiella pneumoniae strain 19 plasmid unnamed, complete sequence	17110-17141	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_MK370728	Klebsiella pneumoniae strain 69G1 plasmid pLimOXA-48, complete sequence	43339-43370	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP030135	Klebsiella pneumoniae strain 160111 plasmid pOXA48_L111, complete sequence	12954-12985	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP042568	Enterobacter hormaechei strain C44 plasmid pC44_002, complete sequence	68391-68422	8	0.75
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NZ_CP018736	Klebsiella pneumoniae strain Kp_Goe_121641 plasmid pKp_Goe_641-2	46582-46613	8	0.75
NZ_CP006850_9	9.1\|1926283\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1926283-1926315	33	NZ_CP032676	Rhodococcus rhodochrous strain ATCC BAA870 plasmid pNit, complete sequence	410828-410860	8	0.758
NZ_CP006850_8	8.1\|1923737\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923737-1923769	33	NZ_HG938354	Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence	197771-197803	9	0.727
NZ_CP006850_8	8.3\|1923859\|34\|NZ_CP006850\|CRISPRCasFinder,CRT	1923859-1923892	34	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	568453-568486	9	0.735
NZ_CP006850_8	8.6\|1923799\|32\|NZ_CP006850\|PILER-CR	1923799-1923830	32	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	236374-236405	9	0.719
NZ_CP006850_8	8.7\|1923860\|33\|NZ_CP006850\|PILER-CR	1923860-1923892	33	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	542548-542580	9	0.727
NZ_CP006850_8	8.1\|1923737\|33\|NZ_CP006850\|CRISPRCasFinder,CRT	1923737-1923769	33	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	707041-707073	10	0.697
NZ_CP006850_8	8.3\|1923859\|34\|NZ_CP006850\|CRISPRCasFinder,CRT	1923859-1923892	34	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	542547-542580	10	0.706
NZ_CP006850_8	8.8\|1923922\|32\|NZ_CP006850\|PILER-CR	1923922-1923953	32	NC_048788	Mycobacterium phage ThetaBob, complete genome	55239-55270	10	0.688
NZ_CP006850_9	9.4\|1926466\|31\|NZ_CP006850\|CRISPRCasFinder,CRT,PILER-CR	1926466-1926496	31	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	802464-802494	10	0.677
NZ_CP006850_11	11.1\|3213557\|36\|NZ_CP006850\|CRISPRCasFinder	3213557-3213592	36	NZ_AP014707	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_3p, complete sequence	62068-62103	11	0.694

1. spacer 12.1|6101645|25|NZ_CP006850|CRISPRCasFinder matches to NZ_CP032314 (Pannonibacter phragmitetus BB plasmid p.BB_2, complete sequence) position: , mismatch: 4, identity: 0.84

cgcaggtcggaccgcggcaaaccga	CRISPR spacer
ttcaggtcggaccgcggcagcccga	Protospacer
. *****************. ****

2. spacer 6.1|1907393|28|NZ_CP006850|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 5, identity: 0.821

gcgccatccgccgcaacgagcatcggct	CRISPR spacer
gcgccatccgccgcaacgggcgcaggcc	Protospacer
******************.**.. ***.

3. spacer 12.1|6101645|25|NZ_CP006850|CRISPRCasFinder matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.8

cgcaggtcggaccgcggcaaaccga	CRISPR spacer
ttgtggtcgcaccgcggcaaaccga	Protospacer
.   ***** ***************

4. spacer 6.1|1907393|28|NZ_CP006850|CRISPRCasFinder matches to NZ_LR723678 (Arsenite-oxidising bacterium NT-25 plasmid 2) position: , mismatch: 6, identity: 0.786

gcgccatccgccgcaacgagcatcggct	CRISPR spacer
gcgccatccgccgcatcgagccgcttgt	Protospacer
*************** *****  *   *

5. spacer 6.1|1907393|28|NZ_CP006850|CRISPRCasFinder matches to NZ_FO082821 (Rhizobium sp. NT-26 plasmid NT26_p1, complete sequence) position: , mismatch: 6, identity: 0.786

gcgccatccgccgcaacgagcatcggct	CRISPR spacer
gcgccatccgccgcatcgagccgcttgt	Protospacer
*************** *****  *   *

6. spacer 6.1|1907393|28|NZ_CP006850|CRISPRCasFinder matches to NZ_CP010872 (Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6003, complete sequence) position: , mismatch: 6, identity: 0.786

gcgccatccgccgcaacgagcatcggct	CRISPR spacer
gcgccatccgccgcatcgagccgcttgt	Protospacer
*************** *****  *   *

7. spacer 6.1|1907393|28|NZ_CP006850|CRISPRCasFinder matches to NZ_CP031599 (Roseovarius indicus strain DSM 26383 plasmid pRIdsm_01, complete sequence) position: , mismatch: 6, identity: 0.786

gcgccatccgccgcaacgagcatcggct	CRISPR spacer
gcgccatccgccgcatcgagccgcttgt	Protospacer
*************** *****  *   *

8. spacer 6.1|1907393|28|NZ_CP006850|CRISPRCasFinder matches to NZ_CP012662 (Defluviimonas alba strain cai42 plasmid pcai42A, complete sequence) position: , mismatch: 6, identity: 0.786

gcgccatccgccgcaacgagcatcggct	CRISPR spacer
gcgccatccgccgcatcgagccgcttgt	Protospacer
*************** *****  *   *

9. spacer 6.1|1907393|28|NZ_CP006850|CRISPRCasFinder matches to NZ_AP022339 (Mameliella alba strain KU6B plasmid pKUB112, complete sequence) position: , mismatch: 6, identity: 0.786

gcgccatccgccgcaacgagcatcggct	CRISPR spacer
gcgccatccgccgcatcgagccgcttgt	Protospacer
*************** *****  *   *

10. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010612 (Phaeobacter inhibens strain P92 plasmid pP92_b, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

11. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010624 (Phaeobacter inhibens strain P51 plasmid pP51_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

12. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010669 (Phaeobacter inhibens strain P57 plasmid pP57_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

13. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP031957 (Phaeobacter sp. LSS9 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ccagcgcggtcagggtgaggtcatgagctatc	Protospacer
 ************ ** ********* * * *

14. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NC_018291 (Phaeobacter inhibens DSM 17395 plasmid pPGA1_262, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

15. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010596 (Phaeobacter inhibens strain P10 plasmid pP10_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

16. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010682 (Phaeobacter piscinae strain P14 plasmid pP14_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ccagcgcggtcagggtgaggtcatgagctatc	Protospacer
 ************ ** ********* * * *

17. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010630 (Phaeobacter inhibens strain P78 plasmid pP78_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

18. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010717 (Phaeobacter piscinae strain P18 plasmid pP18_b, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ccagcgcggtcagggtgaggtcatgagctatc	Protospacer
 ************ ** ********* * * *

19. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP031953 (Phaeobacter inhibens strain 2.10 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

20. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NC_018421 (Phaeobacter inhibens 2.10 plasmid pPGA2_239, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

21. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010657 (Phaeobacter piscinae strain P71 plasmid pP71_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ccagcgcggtcagggtgaggtcatgagctatc	Protospacer
 ************ ** ********* * * *

22. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP031949 (Phaeobacter inhibens strain BS107 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

23. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010618 (Phaeobacter inhibens strain P30 isolate M4-3.1A plasmid pP30_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

24. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010726 (Phaeobacter inhibens strain P88 plasmid pP88_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

25. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010768 (Phaeobacter piscinae strain P13 plasmid pP13_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ccagcgcggtcagggtgaggtcatgagctatc	Protospacer
 ************ ** ********* * * *

26. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010651 (Phaeobacter inhibens strain P54 plasmid pP54_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

27. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010644 (Phaeobacter piscinae strain P36 plasmid pP36_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ccagcgcggtcagggtgaggtcatgagctatc	Protospacer
 ************ ** ********* * * *

28. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010697 (Phaeobacter inhibens strain P24 plasmid pP24_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

29. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP010736 (Phaeobacter inhibens strain P72 plasmid pP72_a, complete sequence) position: , mismatch: 6, identity: 0.812

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tcagcgcggtcagggtgaggtcatgagctacc	Protospacer
 ************ ** ********* * * *

30. spacer 9.5|1926525|33|NZ_CP006850|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 6, identity: 0.818

gcgtcgtgactgtcggcgctgcgaaccctacga--	CRISPR spacer
tcgtcgagactgtcggcgctgcg--cacgacgatg	Protospacer
 ***** ****************  * * ****

31. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010612 (Phaeobacter inhibens strain P92 plasmid pP92_b, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

32. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010624 (Phaeobacter inhibens strain P51 plasmid pP51_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

33. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010669 (Phaeobacter inhibens strain P57 plasmid pP57_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

34. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP031957 (Phaeobacter sp. LSS9 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tccagcgcggtcagggtgaggtcatgagctatc	Protospacer
. ************ ** ********* * * *

35. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_018291 (Phaeobacter inhibens DSM 17395 plasmid pPGA1_262, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

36. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010596 (Phaeobacter inhibens strain P10 plasmid pP10_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

37. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010682 (Phaeobacter piscinae strain P14 plasmid pP14_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tccagcgcggtcagggtgaggtcatgagctatc	Protospacer
. ************ ** ********* * * *

38. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010630 (Phaeobacter inhibens strain P78 plasmid pP78_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

39. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010717 (Phaeobacter piscinae strain P18 plasmid pP18_b, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tccagcgcggtcagggtgaggtcatgagctatc	Protospacer
. ************ ** ********* * * *

40. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP031953 (Phaeobacter inhibens strain 2.10 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

41. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_018421 (Phaeobacter inhibens 2.10 plasmid pPGA2_239, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

42. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010657 (Phaeobacter piscinae strain P71 plasmid pP71_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tccagcgcggtcagggtgaggtcatgagctatc	Protospacer
. ************ ** ********* * * *

43. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP031949 (Phaeobacter inhibens strain BS107 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

44. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010618 (Phaeobacter inhibens strain P30 isolate M4-3.1A plasmid pP30_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

45. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010726 (Phaeobacter inhibens strain P88 plasmid pP88_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

46. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010768 (Phaeobacter piscinae strain P13 plasmid pP13_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tccagcgcggtcagggtgaggtcatgagctatc	Protospacer
. ************ ** ********* * * *

47. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010651 (Phaeobacter inhibens strain P54 plasmid pP54_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

48. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010644 (Phaeobacter piscinae strain P36 plasmid pP36_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
tccagcgcggtcagggtgaggtcatgagctatc	Protospacer
. ************ ** ********* * * *

49. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010697 (Phaeobacter inhibens strain P24 plasmid pP24_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

50. spacer 8.2|1923798|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010736 (Phaeobacter inhibens strain P72 plasmid pP72_a, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
ttcagcgcggtcagggtgaggtcatgagctacc	Protospacer
. ************ ** ********* * * *

51. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KX783441 (Klebsiella pneumoniae strain KP4368 plasmid pKP4368, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

52. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP015071 (Escherichia coli strain Ecol_743 plasmid pEC743_OXA48, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

53. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KM406488 (Salmonella enterica subsp. enterica serovar Paratyphi B strain R69 plasmid R69, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

54. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KP975075 (Citrobacter freundii strain MRSN12115 plasmid pMRVIM1012, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

55. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP029447 (Serratia marcescens strain CAV1761 plasmid pCAV1761-73, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

56. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP031566 (Enterobacter hormaechei strain 2013_1a plasmid pIncLM-1301491, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

57. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP019841 (Enterobacter roggenkampii strain R11 plasmid pASM2, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

58. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP010365 (Enterobacter hormaechei subsp. oharae strain 34978 plasmid p34978-70.092kb, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

59. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018669 (Klebsiella pneumoniae strain CAV1042 plasmid pKPC_CAV1042-89, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

60. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018452 (Klebsiella pneumoniae strain Kp_Goe_71070 plasmid pKp_Goe_070-2, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

61. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP016927 (Klebsiella pneumoniae isolate 23 plasmid pIncL_M_DHQP1400954, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

62. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP027148 (Klebsiella pneumoniae strain AR_0363 plasmid unnamed5) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

63. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to MN187903 (Citrobacter freundii strain Cf164 plasmid pCf164_CTX-M-8, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

64. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP032170 (Klebsiella pneumoniae strain AR_0076 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

65. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to CP020502 (Serratia marcescens strain BWH-23 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

66. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP029720 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

67. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP021742 (Klebsiella pneumoniae strain AR_0126 plasmid tig00000002jNODE_23, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

68. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KY781949 (Klebsiella pneumoniae isolate Kp41 plasmid pKp41M, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

69. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP014072 (Klebsiella quasipneumoniae strain FDAARGOS_93 plasmid unnamed1) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

70. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP050846 (Klebsiella pneumoniae strain Bckp206 plasmid pBckp206-1, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

71. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KT935445 (Klebsiella pneumoniae strain Kp6411 plasmid 6411TF, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

72. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KP025948 (Proteus mirabilis strain Pm-Oxa48 plasmid pOXA48-Pm, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

73. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP011599 (Phytobacter ursingii strain CAV1151 plasmid pCAV1151-83, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

74. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP037737 (Citrobacter freundii strain CAV1857 plasmid pKPC_CAV1857-85, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

75. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP020530 (Enterobacter cloacae strain 174 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

76. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_005246 (Erwinia amylovora LebB66 plasmid pEL60, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

77. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP029138 (Klebsiella pneumoniae strain AR376 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

78. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP029599 (Klebsiella quasipneumoniae subsp. similipneumoniae strain ATCC 700603 plasmid pDA33145-77, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

79. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP022826 (Klebsiella quasivariicola strain KPN1705 plasmid pKPN1705-3, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

80. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_AP019667 (Klebsiella pneumoniae strain TA6363 plasmid pTMTA63632, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

81. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP011614 (Klebsiella oxytoca strain CAV1335 plasmid pCAV1335-92, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

82. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP017932 (Klebsiella oxytoca strain CAV1015 plasmid pCAV1015-76, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

83. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP017936 (Klebsiella pneumoniae strain CAV1016 plasmid pCAV1016-76, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

84. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP011640 (Serratia marcescens strain CAV1492 plasmid pCAV1492-73, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

85. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP045017 (Klebsiella pneumoniae subsp. pneumoniae strain BK13048 plasmid pBK13048-2, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

86. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP011632 (Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-84, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

87. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP014698 (Klebsiella quasipneumoniae strain ATCC 700603 isolate K6 plasmid pKQPS2, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

88. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP011593 (Klebsiella oxytoca strain CAV1099 plasmid pCAV1099-69, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

89. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP011656 (Citrobacter freundii strain CAV1741 plasmid pKPC_CAV1741, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

90. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP011609 (Citrobacter freundii strain CAV1321 plasmid pCAV1321-71, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

91. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_019346 (Enterobacter cloacae plasmid pNE1280, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

92. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP027699 (Klebsiella pneumoniae strain KP30835 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

93. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LT985279 (Escherichia coli strain 676 plasmid RCS60_p, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

94. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018449 (Klebsiella pneumoniae strain Kp_Goe_33208 plasmid pKp_Goe_208-2, complete sequence) position: , mismatch: 7, identity: 0.788

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacgcg	Protospacer
*.********** ********* ***.. ** *

95. spacer 8.7|1923860|33|NZ_CP006850|PILER-CR matches to NZ_CP044989 (Deinococcus sp. AJ005 plasmid p380k, complete sequence) position: , mismatch: 7, identity: 0.788

ctgggcctggacctgatccgcctgcaccgcacc-	CRISPR spacer
cagggactggacctgatccgccagcatc-tactg	Protospacer
* *** **************** ***.* .**.

96. spacer 8.7|1923860|33|NZ_CP006850|PILER-CR matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 7, identity: 0.788

ctgggcctggacctgatccgcctgcaccgcacc	CRISPR spacer
ctgccgctggaactgacccgcctgcaccgctcg	Protospacer
***   ***** ****.************* *

97. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KY781949 (Klebsiella pneumoniae isolate Kp41 plasmid pKp41M, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

98. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP014072 (Klebsiella quasipneumoniae strain FDAARGOS_93 plasmid unnamed1) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

99. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP050846 (Klebsiella pneumoniae strain Bckp206 plasmid pBckp206-1, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

100. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KX783441 (Klebsiella pneumoniae strain KP4368 plasmid pKP4368, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

101. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KT935445 (Klebsiella pneumoniae strain Kp6411 plasmid 6411TF, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

102. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP015071 (Escherichia coli strain Ecol_743 plasmid pEC743_OXA48, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

103. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KM406488 (Salmonella enterica subsp. enterica serovar Paratyphi B strain R69 plasmid R69, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

104. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KP025948 (Proteus mirabilis strain Pm-Oxa48 plasmid pOXA48-Pm, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

105. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KP975075 (Citrobacter freundii strain MRSN12115 plasmid pMRVIM1012, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

106. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP011599 (Phytobacter ursingii strain CAV1151 plasmid pCAV1151-83, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

107. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP016593 (Ketogulonicigenium vulgare strain SKV plasmid pKvSKV1, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgcttggccttggccgctgcgcgaccgt	Protospacer
.***** *******.********** * * *

108. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_017386 (Ketogulonicigenium vulgare WSH-001 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgcttggccttggccgctgcgcgaccgt	Protospacer
.***** *******.********** * * *

109. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP037737 (Citrobacter freundii strain CAV1857 plasmid pKPC_CAV1857-85, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

110. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_014621 (Ketogulonicigenium vulgare Y25 plasmid pYP1, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgcttggccttggccgctgcgcgaccgt	Protospacer
.***** *******.********** * * *

111. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP029447 (Serratia marcescens strain CAV1761 plasmid pCAV1761-73, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

112. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP012909 (Ketogulonicigenium vulgare strain Hbe602 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgcttggccttggccgctgcgcgaccgt	Protospacer
.***** *******.********** * * *

113. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP020530 (Enterobacter cloacae strain 174 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

114. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP031566 (Enterobacter hormaechei strain 2013_1a plasmid pIncLM-1301491, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

115. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_005246 (Erwinia amylovora LebB66 plasmid pEL60, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

116. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP029138 (Klebsiella pneumoniae strain AR376 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

117. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP019841 (Enterobacter roggenkampii strain R11 plasmid pASM2, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

118. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP010365 (Enterobacter hormaechei subsp. oharae strain 34978 plasmid p34978-70.092kb, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

119. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP029599 (Klebsiella quasipneumoniae subsp. similipneumoniae strain ATCC 700603 plasmid pDA33145-77, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

120. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP022826 (Klebsiella quasivariicola strain KPN1705 plasmid pKPN1705-3, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

121. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_AP019667 (Klebsiella pneumoniae strain TA6363 plasmid pTMTA63632, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

122. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP011614 (Klebsiella oxytoca strain CAV1335 plasmid pCAV1335-92, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

123. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP017932 (Klebsiella oxytoca strain CAV1015 plasmid pCAV1015-76, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

124. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP017936 (Klebsiella pneumoniae strain CAV1016 plasmid pCAV1016-76, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

125. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018669 (Klebsiella pneumoniae strain CAV1042 plasmid pKPC_CAV1042-89, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

126. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018452 (Klebsiella pneumoniae strain Kp_Goe_71070 plasmid pKp_Goe_070-2, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

127. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP011640 (Serratia marcescens strain CAV1492 plasmid pCAV1492-73, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

128. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP045017 (Klebsiella pneumoniae subsp. pneumoniae strain BK13048 plasmid pBK13048-2, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

129. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP011632 (Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-84, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

130. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP016927 (Klebsiella pneumoniae isolate 23 plasmid pIncL_M_DHQP1400954, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

131. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP027148 (Klebsiella pneumoniae strain AR_0363 plasmid unnamed5) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

132. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP014698 (Klebsiella quasipneumoniae strain ATCC 700603 isolate K6 plasmid pKQPS2, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

133. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP011593 (Klebsiella oxytoca strain CAV1099 plasmid pCAV1099-69, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

134. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP011656 (Citrobacter freundii strain CAV1741 plasmid pKPC_CAV1741, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

135. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP011609 (Citrobacter freundii strain CAV1321 plasmid pCAV1321-71, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

136. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to MN187903 (Citrobacter freundii strain Cf164 plasmid pCf164_CTX-M-8, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

137. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP032170 (Klebsiella pneumoniae strain AR_0076 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

138. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to CP020502 (Serratia marcescens strain BWH-23 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

139. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_019346 (Enterobacter cloacae plasmid pNE1280, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

140. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP029720 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

141. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP027699 (Klebsiella pneumoniae strain KP30835 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

142. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LT985279 (Escherichia coli strain 676 plasmid RCS60_p, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

143. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP021742 (Klebsiella pneumoniae strain AR_0126 plasmid tig00000002jNODE_23, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

144. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018449 (Klebsiella pneumoniae strain Kp_Goe_33208 plasmid pKp_Goe_208-2, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacgcg	Protospacer
.********** ********* ***.. ** *

145. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 7, identity: 0.781

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
tggaggaccggcatcgcccgctgcgggtcggg	Protospacer
 * * **..*** *** ***************

146. spacer 9.1|1926283|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP039632 (Pseudomonas veronii strain Pvy plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

ccgcacaccgacatcgagggccgctacctgatc	CRISPR spacer
gcgggcgccgacatcgaggcccggtacctgaac	Protospacer
 ** .*.************ *** ******* *

147. spacer 9.1|1926283|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP007510 (Pseudomonas stutzeri strain 19SMN4 plasmid pLIB119, complete plasmid) position: , mismatch: 7, identity: 0.788

ccgcacaccgacatcgagggccgctacctgatc	CRISPR spacer
gcgggcgccgacatcgaggcccggtacctgaac	Protospacer
 ** .*.************ *** ******* *

148. spacer 9.1|1926283|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_AP015030 (Pseudomonas putida strain KF715 plasmid pKF715A, complete sequence) position: , mismatch: 7, identity: 0.788

ccgcacaccgacatcgagggccgctacctgatc	CRISPR spacer
gcgggcgccgacatcgaggcccggtacctgaac	Protospacer
 ** .*.************ *** ******* *

149. spacer 9.4|1926466|31|NZ_CP006850|CRISPRCasFinder,CRT,PILER-CR matches to MH651189 (Gordonia phage Schmidt, complete genome) position: , mismatch: 7, identity: 0.774

cgaacgaaagcgattccgcgcgcgcactgtc-	CRISPR spacer
actacgaacgcgattccgcgtgcgca-ggtcg	Protospacer
   ***** ***********.*****  ***

150. spacer 9.6|1926586|33|NZ_CP006850|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012886 (Mycobacterium chimaera strain AH16 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

ggccggggtgcgcgcctgggtgccgagcgtgaa----	CRISPR spacer
cgccggggtgcgcggctgggtgc----cgtgacctct	Protospacer
 ************* ********    *****

151. spacer 8.3|1923859|34|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP044989 (Deinococcus sp. AJ005 plasmid p380k, complete sequence) position: , mismatch: 8, identity: 0.765

gctgggcctggacctgatccgcctgcaccgcacc-	CRISPR spacer
acagggactggacctgatccgccagcatc-tactg	Protospacer
.* *** **************** ***.* .**.

152. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KM406490 (Salmonella enterica subsp. enterica serovar Typhimurium strain 202 plasmid pSEM, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

153. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KM406489 (Serratia marcescens strain R471 plasmid R471, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

154. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to CP048042 (Serratia liquefaciens strain JL02 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

155. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP016593 (Ketogulonicigenium vulgare strain SKV plasmid pKvSKV1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
cggcacgcttggccttggccgctgcgcgaccgt	Protospacer
 .***** *******.********** * * *

156. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_017386 (Ketogulonicigenium vulgare WSH-001 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
cggcacgcttggccttggccgctgcgcgaccgt	Protospacer
 .***** *******.********** * * *

157. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP034202 (Klebsiella pneumoniae subsp. pneumoniae strain KpvST383_NDM_OXA-48 plasmid pKpvST383L_2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

158. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP035217 (Klebsiella michiganensis strain M82255 plasmid pKOCBH-C, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

159. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_014621 (Ketogulonicigenium vulgare Y25 plasmid pYP1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
cggcacgcttggccttggccgctgcgcgaccgt	Protospacer
 .***** *******.********** * * *

160. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP012909 (Ketogulonicigenium vulgare strain Hbe602 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
cggcacgcttggccttggccgctgcgcgaccgt	Protospacer
 .***** *******.********** * * *

161. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018717 (Klebsiella pneumoniae strain Kp_Goe_152021 plasmid pKp_Goe_021-3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

162. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018723 (Klebsiella pneumoniae strain KP_Goe_828304 plasmid pKp_Goe_304-3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

163. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018706 (Klebsiella pneumoniae strain Kp_Goe_827024 plasmid pKp_Goe_024-3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

164. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC556214 (Escherichia coli CEX24 plasmid pCEX24 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

165. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC556215 (Escherichia coli CEX25 plasmid pCEX25 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

166. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC556216 (Escherichia coli CEX14 plasmid pCEX14 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

167. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC556217 (Escherichia coli CEX3 plasmid pCEX3 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

168. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC556218 (Enterobacter cloacae CEX5 plasmid pCEX5 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

169. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC556219 (Enterobacter cloacae CEX6 plasmid pCEX6 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

170. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC556220 (Enterobacter cloacae CEX4 plasmid pCEX4 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

171. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC556221 (Klebsiella pneumoniae CEX18 plasmid pCEX18 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

172. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC556222 (Klebsiella pneumoniae CEX23 plasmid pCEX23 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

173. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_024997 (Klebsiella oxytoca plasmid pACM1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

174. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP034325 (Klebsiella pneumoniae isolate KSH203 plasmid pKSH203-CTX-M-3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

175. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_025134 (Klebsiella pneumoniae plasmid pFOX-7a, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

176. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP017853 (Klebsiella variicola strain GJ2 plasmid pKPGJ-2d, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

177. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP009852 (UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH4 plasmid pENT-e56, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

178. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP026395 (Klebsiella pneumoniae strain KPNIH48 plasmid pKPC-edb7, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

179. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP026142 (Klebsiella pneumoniae strain F127 plasmid pF127_2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

180. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP026210 (Citrobacter sp. CFNIH10 plasmid pKPC-2fe2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

181. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018315 (Klebsiella pneumoniae strain Kp_Goe_822579 plasmid pKp_Goe_579-3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

182. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP015075 (Escherichia coli strain Ecol_745 plasmid pEC745_OXA48, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

183. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to KU159086 (Klebsiella pneumoniae plasmid pOXAAPSS2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

184. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018690 (Klebsiella pneumoniae strain Kp_Goe_149473 plasmid pKp_Goe_473-3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

185. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP031374 (Klebsiella pneumoniae strain KpvST101_OXA-48 plasmid pKpvOXA-48, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

186. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP032193 (Salmonella enterica subsp. enterica serovar Senftenberg strain AR_0127 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

187. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018342 (Klebsiella pneumoniae isolate Kp_Goe_154414 plasmid pKp_Goe_414-5, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

188. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP033880 (Escherichia coli strain 50579417 plasmid p50579417_3_OXA-48, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

189. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP042490 (Enterobacter hormaechei strain C15 plasmid pC15_002) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

190. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018712 (Klebsiella pneumoniae strain Kp_Goe_827026 plasmid pKp_Goe_026-3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

191. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KY215945 (Klebsiella pneumoniae subsp. pneumoniae strain Kp1210 plasmid pOXA-519, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

192. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KY213890 (Klebsiella pneumoniae strain 38_wz plasmid pOXA48_wz, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

193. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LT838202 (Escherichia coli isolate WI2 isolate plasmid pWI2-OXA48, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

194. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LN864821 (Raoultella planticola plasmid pRA35, complete sequence, strain RA35) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

195. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KX523901 (Klebsiella pneumoniae strain Kpn-30715/15 plasmid pOXA-48_30715, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

196. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KX523900 (Klebsiella pneumoniae strain Kpn-04963/15 plasmid pOXA-48_4963, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

197. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KX523902 (Klebsiella pneumoniae strain Kpn-30891/15 plasmid pOXA-48_30891, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

198. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KX636096 (Klebsiella pneumoniae strain RJ119 plasmid pRJ119-2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

199. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KX009507 (Escherichia coli strain 06K2206 plasmid LM6771, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

200. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_019368 (Enterobacter cloacae plasmid pEl1573, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

201. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KM406491 (Klebsiella pneumoniae strain Kpn-E1.Nr7 plasmid pKpn-E1.Nr7, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

202. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KP659188 (Klebsiella pneumoniae strain 153877-1 plasmid pOXA-48E1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

203. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KP061858 (Enterobacter cloacae strain INSRA17313-1 plasmid pUR17313-1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

204. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KM877517 (Enterobacter cloacae strain CRE623 plasmid pIMP-HB623, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

205. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KP294351 (Escherichia coli strain CZD1527 plasmid pIGT15, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

206. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_KU315015 (Serratia marcescens strain NCTC 50331 plasmid R1215, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

207. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to AP018454 (Klebsiella pneumoniae plasmid pMRY13-133KPN_2 DNA, complete genome, strain: MRY13-133) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

208. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to AP018455 (Klebsiella aerogenes plasmid pMRY13-134EAE_1 DNA, complete genome, strain: MRY13-134) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

209. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP034041 (Klebsiella pneumoniae subsp. pneumoniae strain CRK0298 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

210. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP026156 (Klebsiella pneumoniae strain B12(AN) plasmid pB12AN_1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

211. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP044032 (Klebsiella pneumoniae strain FDAARGOS_631 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

212. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP048353 (Raoultella ornithinolytica strain 23 plasmid p23_D-OXA48, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

213. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP034283 (Klebsiella pneumoniae strain I72 plasmid p72_LM_OXA48, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

214. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_004464 (Citrobacter freundii plasmid pCTX-M3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

215. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP023419 (Klebsiella pneumoniae strain 1050 plasmid pKp1050-3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

216. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP042501 (Enterobacter sp. E76 plasmid pE76_002, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

217. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP048339 (Escherichia coli strain 142 plasmid p142_B, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

218. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to MK249855 (Enterobacter cloacae strain 105 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

219. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to MK249856 (Klebsiella pneumoniae strain 91 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

220. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to MK249858 (Escherichia coli strain 46 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

221. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP042509 (Leclercia adecarboxylata strain E1 plasmid pE1_004, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

222. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_021488 (Klebsiella pneumoniae plasmid pKPoxa-48N1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

223. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_021502 (Klebsiella pneumoniae plasmid pKPoxa-48N2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

224. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP026194 (Enterobacteriaceae bacterium ENNIH1 plasmid pKPC-825d, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

225. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP027039 (Klebsiella pneumoniae strain 16_GR_13 plasmid IncLM, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

226. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP020844 (Klebsiella pneumoniae strain KPN1482 plasmid pKPN1482-3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

227. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_019154 (Klebsiella pneumoniae plasmid pOXA-48, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

228. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP041085 (Klebsiella pneumoniae strain Kp202 plasmid pKp202_3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

229. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP023251 (Klebsiella pneumoniae strain CCUG 70742 plasmid pKpn70742_2) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

230. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LT994838 (Klebsiella variicola isolate CNR130 plasmid CNR130, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

231. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to MK966141 (Enterobacter cloacae strain GHZ8R11B plasmid pHNGDR11, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

232. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to MK966142 (Klebsiella pneumoniae strain GHP8R3B plasmid pHNGDR03, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

233. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP024878 (Klebsiella pneumoniae strain NH25 plasmid pNH25.4, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

234. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP042514 (Serratia marcescens strain E28 plasmid pE28_002, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

235. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LT985387 (Escherichia coli strain 694 genome assembly, plasmid: RCS55_pI) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

236. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP031805 (Klebsiella pneumoniae strain MSB1_8A-sc-2280397 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

237. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP045511 (Salmonella enterica subsp. enterica serovar Anatum strain M-5360 plasmid p55k, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

238. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC508263 (Klebsiella pneumoniae A1-3 plasmid pA1-3 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

239. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP007733 (Klebsiella pneumoniae subsp. pneumoniae KPNIH27 plasmid pKPN-068, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

240. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP040036 (Klebsiella pneumoniae strain KPC160117 plasmid pOXA48-L117, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

241. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP022153 (Citrobacter freundii strain 705SK3 plasmid p705SK3_2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

242. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP017288 (Klebsiella variicola strain GJ3 plasmid pKPGJ-3d, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

243. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_019063 (Escherichia coli plasmid pNDM-HK, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

244. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP022150 (Enterobacter roggenkampii strain 704SK10 plasmid p704SK10_2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

245. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to MG516907 (Klebsiella aerogenes plasmid pEa1631, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

246. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LR025105 (Escherichia coli isolate EC-1639 plasmid pOXA-48_1639, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

247. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP009857 (UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-d0d, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

248. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP042532 (Klebsiella aerogenes strain C9 plasmid pC9_002, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

249. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP026385 (Serratia sp. SSNIH1 plasmid pKPC-56ce, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

250. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP017282 (Klebsiella variicola strain GJ1 plasmid pKPGJ-1c, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

251. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LT994833 (Klebsiella pneumoniae isolate CNR341 plasmid CNR341, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

252. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP031235 (Escherichia coli strain Es_ST410_NW1_NDM_09_2017 plasmid pEsST410_NW_NDM, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

253. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to KP294350 (Uncultured bacterium plasmid pARM26, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

254. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to MN792918 (Klebsiella aerogenes strain ST143 plasmid pLAU_KAM9_OXA48, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

255. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018974 (Escherichia coli strain Ecol_545 plasmid pEC545_KPC, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

256. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP040031 (Klebsiella pneumoniae strain KPC160121 plasmid pOXA48-L121, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

257. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018461 (Klebsiella pneumoniae strain Kp_Goe_39795 plasmid pKp_Goe_795-2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

258. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP032174 (Klebsiella pneumoniae strain AR_0160 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

259. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC536683 (Klebsiella pneumoniae MyNCGM084 plasmid pMyNCGM084, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

260. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP048418 (Citrobacter freundii strain CitB plasmid pB_CitB, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

261. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LR025095 (Klebsiella pneumoniae isolate KP9201 plasmid pOXA-48_920, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

262. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC545849 (Escherichia coli Ec-MW04 plasmid pEc-MW04_OXA DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

263. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP042574 (Enterobacter hormaechei strain E5 plasmid pE5_003, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

264. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP042542 (Enterobacter hormaechei strain C4 plasmid pC4_002, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

265. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP014298 (Klebsiella pneumoniae strain KP38731 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

266. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP042580 (Enterobacter kobei strain C16 plasmid pC16_002, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

267. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to KU159085 (Klebsiella pneumoniae plasmid pOXAAPSS1, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

268. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_023027 (Klebsiella pneumoniae strain E71T plasmid, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

269. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP026497 (Klebsiella pneumoniae strain 616 plasmid pKp616_2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

270. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP026188 (Enterobacteriaceae bacterium ENNIH2 plasmid pKPC-ddab, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

271. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP044337 (Enterobacter hormaechei strain AKB48 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

272. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LN864819 (Klebsiella pneumoniae plasmid pKP112, complete sequence, strain KP112) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

273. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP031216 (Escherichia coli strain Es_ST80_L1_NDM_10_2017 plasmid pEsST80_L1_NDM, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

274. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LR025091 (Klebsiella pneumoniae isolate KP980 plasmid pOXA-48_980, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

275. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP038457 (Escherichia coli strain EC-129 plasmid pEC129_4, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

276. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_011641 (Klebsiella pneumoniae plasmid pCTXM360, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

277. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_019344 (Serratia marcescens plasmid R830b, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

278. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP042526 (Citrobacter freundii strain E11 plasmid pE11_002, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

279. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP031322 (Escherichia coli strain ST2350 isolate Es_ST2350_SE1_NDM_03_2018 plasmid pEsST2350_SE_NDM, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

280. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to CP052472 (Klebsiella pneumoniae strain C16KP0053 plasmid pC16KP0053-4, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

281. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018700 (Klebsiella pneumoniae strain Kp_Goe_149832 plasmid pKp_Goe_832-3, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

282. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LR745044 (Klebsiella pneumoniae isolate Klebsiella pneumoniae kpn154 plasmid pOXA48_Kpn154) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

283. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_021078 (Klebsiella pneumoniae strain Kp002 plasmid pJEG011, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

284. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LT985264 (Escherichia coli strain 717 plasmid RCS51TR717_p, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

285. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_LT985241 (Escherichia coli strain 721 plasmid RCS40_p, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

286. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC505604 (Klebsiella pneumoniae A1-1 plasmid pKp1-1 genomic DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

287. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to LC508722 (Klebsiella pneumoniae A2-1 plasmid pA2-4 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

288. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NC_019889 (Klebsiella pneumoniae strain 601 plasmid pNDM-OM, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

289. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to MT193824 (Escherichia coli strain 19-AB01443 plasmid pOX-48-EC1443, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

290. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_MK088079 (Klebsiella pneumoniae strain 19 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

291. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_MK370728 (Klebsiella pneumoniae strain 69G1 plasmid pLimOXA-48, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

292. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP030135 (Klebsiella pneumoniae strain 160111 plasmid pOXA48_L111, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

293. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP042568 (Enterobacter hormaechei strain C44 plasmid pC44_002, complete sequence) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

294. spacer 8.4|1923921|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018736 (Klebsiella pneumoniae strain Kp_Goe_121641 plasmid pKp_Goe_641-2) position: , mismatch: 8, identity: 0.758

gagcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
gggcacgattggactcggccgcggcgaaacccg	Protospacer
*.********** ********* ***.. *  *

295. spacer 8.7|1923860|33|NZ_CP006850|PILER-CR matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

ctgggcctggacctgatccgcctgcaccgcacc	CRISPR spacer
gatgtcctggacctgaacagcctgcaccgcgac	Protospacer
   * *********** * ***********. *

296. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KY215945 (Klebsiella pneumoniae subsp. pneumoniae strain Kp1210 plasmid pOXA-519, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

297. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KY213890 (Klebsiella pneumoniae strain 38_wz plasmid pOXA48_wz, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

298. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LT838202 (Escherichia coli isolate WI2 isolate plasmid pWI2-OXA48, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

299. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LN864821 (Raoultella planticola plasmid pRA35, complete sequence, strain RA35) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

300. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KX523901 (Klebsiella pneumoniae strain Kpn-30715/15 plasmid pOXA-48_30715, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

301. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KX523900 (Klebsiella pneumoniae strain Kpn-04963/15 plasmid pOXA-48_4963, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

302. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KX523902 (Klebsiella pneumoniae strain Kpn-30891/15 plasmid pOXA-48_30891, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

303. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KX636096 (Klebsiella pneumoniae strain RJ119 plasmid pRJ119-2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

304. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KX009507 (Escherichia coli strain 06K2206 plasmid LM6771, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

305. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_019368 (Enterobacter cloacae plasmid pEl1573, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

306. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KM406491 (Klebsiella pneumoniae strain Kpn-E1.Nr7 plasmid pKpn-E1.Nr7, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

307. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KP659188 (Klebsiella pneumoniae strain 153877-1 plasmid pOXA-48E1, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

308. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KM406490 (Salmonella enterica subsp. enterica serovar Typhimurium strain 202 plasmid pSEM, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

309. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KM406489 (Serratia marcescens strain R471 plasmid R471, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

310. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KP061858 (Enterobacter cloacae strain INSRA17313-1 plasmid pUR17313-1, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

311. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KM877517 (Enterobacter cloacae strain CRE623 plasmid pIMP-HB623, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

312. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KP294351 (Escherichia coli strain CZD1527 plasmid pIGT15, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

313. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_KU315015 (Serratia marcescens strain NCTC 50331 plasmid R1215, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

314. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to AP018454 (Klebsiella pneumoniae plasmid pMRY13-133KPN_2 DNA, complete genome, strain: MRY13-133) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

315. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to AP018455 (Klebsiella aerogenes plasmid pMRY13-134EAE_1 DNA, complete genome, strain: MRY13-134) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

316. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to CP048042 (Serratia liquefaciens strain JL02 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

317. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP034041 (Klebsiella pneumoniae subsp. pneumoniae strain CRK0298 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

318. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP026156 (Klebsiella pneumoniae strain B12(AN) plasmid pB12AN_1, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

319. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP044032 (Klebsiella pneumoniae strain FDAARGOS_631 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

320. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP048353 (Raoultella ornithinolytica strain 23 plasmid p23_D-OXA48, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

321. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP034283 (Klebsiella pneumoniae strain I72 plasmid p72_LM_OXA48, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

322. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_004464 (Citrobacter freundii plasmid pCTX-M3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

323. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP034202 (Klebsiella pneumoniae subsp. pneumoniae strain KpvST383_NDM_OXA-48 plasmid pKpvST383L_2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

324. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP023419 (Klebsiella pneumoniae strain 1050 plasmid pKp1050-3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

325. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP035217 (Klebsiella michiganensis strain M82255 plasmid pKOCBH-C, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

326. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP042501 (Enterobacter sp. E76 plasmid pE76_002, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

327. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP048339 (Escherichia coli strain 142 plasmid p142_B, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

328. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to MK249855 (Enterobacter cloacae strain 105 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

329. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to MK249856 (Klebsiella pneumoniae strain 91 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

330. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to MK249858 (Escherichia coli strain 46 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

331. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP042509 (Leclercia adecarboxylata strain E1 plasmid pE1_004, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

332. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018717 (Klebsiella pneumoniae strain Kp_Goe_152021 plasmid pKp_Goe_021-3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

333. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018723 (Klebsiella pneumoniae strain KP_Goe_828304 plasmid pKp_Goe_304-3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

334. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018706 (Klebsiella pneumoniae strain Kp_Goe_827024 plasmid pKp_Goe_024-3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

335. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_021488 (Klebsiella pneumoniae plasmid pKPoxa-48N1, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

336. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_021502 (Klebsiella pneumoniae plasmid pKPoxa-48N2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

337. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP026194 (Enterobacteriaceae bacterium ENNIH1 plasmid pKPC-825d, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

338. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP027039 (Klebsiella pneumoniae strain 16_GR_13 plasmid IncLM, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

339. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC556214 (Escherichia coli CEX24 plasmid pCEX24 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

340. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC556215 (Escherichia coli CEX25 plasmid pCEX25 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

341. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC556216 (Escherichia coli CEX14 plasmid pCEX14 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

342. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC556217 (Escherichia coli CEX3 plasmid pCEX3 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

343. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC556218 (Enterobacter cloacae CEX5 plasmid pCEX5 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

344. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC556219 (Enterobacter cloacae CEX6 plasmid pCEX6 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

345. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC556220 (Enterobacter cloacae CEX4 plasmid pCEX4 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

346. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC556221 (Klebsiella pneumoniae CEX18 plasmid pCEX18 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

347. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC556222 (Klebsiella pneumoniae CEX23 plasmid pCEX23 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

348. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP020844 (Klebsiella pneumoniae strain KPN1482 plasmid pKPN1482-3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

349. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_019154 (Klebsiella pneumoniae plasmid pOXA-48, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

350. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_024997 (Klebsiella oxytoca plasmid pACM1, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

351. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP041085 (Klebsiella pneumoniae strain Kp202 plasmid pKp202_3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

352. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP023251 (Klebsiella pneumoniae strain CCUG 70742 plasmid pKpn70742_2) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

353. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LT994838 (Klebsiella variicola isolate CNR130 plasmid CNR130, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

354. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to MK966141 (Enterobacter cloacae strain GHZ8R11B plasmid pHNGDR11, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

355. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to MK966142 (Klebsiella pneumoniae strain GHP8R3B plasmid pHNGDR03, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

356. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP024878 (Klebsiella pneumoniae strain NH25 plasmid pNH25.4, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

357. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP034325 (Klebsiella pneumoniae isolate KSH203 plasmid pKSH203-CTX-M-3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

358. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_025134 (Klebsiella pneumoniae plasmid pFOX-7a, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

359. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP042514 (Serratia marcescens strain E28 plasmid pE28_002, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

360. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LT985387 (Escherichia coli strain 694 genome assembly, plasmid: RCS55_pI) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

361. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP031805 (Klebsiella pneumoniae strain MSB1_8A-sc-2280397 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

362. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP045511 (Salmonella enterica subsp. enterica serovar Anatum strain M-5360 plasmid p55k, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

363. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC508263 (Klebsiella pneumoniae A1-3 plasmid pA1-3 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

364. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP007733 (Klebsiella pneumoniae subsp. pneumoniae KPNIH27 plasmid pKPN-068, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

365. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP040036 (Klebsiella pneumoniae strain KPC160117 plasmid pOXA48-L117, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

366. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP022153 (Citrobacter freundii strain 705SK3 plasmid p705SK3_2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

367. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP017288 (Klebsiella variicola strain GJ3 plasmid pKPGJ-3d, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

368. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_019063 (Escherichia coli plasmid pNDM-HK, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

369. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP022150 (Enterobacter roggenkampii strain 704SK10 plasmid p704SK10_2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

370. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to MG516907 (Klebsiella aerogenes plasmid pEa1631, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

371. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP017853 (Klebsiella variicola strain GJ2 plasmid pKPGJ-2d, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

372. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LR025105 (Escherichia coli isolate EC-1639 plasmid pOXA-48_1639, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

373. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP009852 (UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH4 plasmid pENT-e56, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

374. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP009857 (UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-d0d, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

375. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP042532 (Klebsiella aerogenes strain C9 plasmid pC9_002, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

376. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP026385 (Serratia sp. SSNIH1 plasmid pKPC-56ce, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

377. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP026395 (Klebsiella pneumoniae strain KPNIH48 plasmid pKPC-edb7, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

378. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP017282 (Klebsiella variicola strain GJ1 plasmid pKPGJ-1c, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

379. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LT994833 (Klebsiella pneumoniae isolate CNR341 plasmid CNR341, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

380. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP031235 (Escherichia coli strain Es_ST410_NW1_NDM_09_2017 plasmid pEsST410_NW_NDM, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

381. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to KP294350 (Uncultured bacterium plasmid pARM26, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

382. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to MN792918 (Klebsiella aerogenes strain ST143 plasmid pLAU_KAM9_OXA48, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

383. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018974 (Escherichia coli strain Ecol_545 plasmid pEC545_KPC, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

384. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP026142 (Klebsiella pneumoniae strain F127 plasmid pF127_2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

385. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP040031 (Klebsiella pneumoniae strain KPC160121 plasmid pOXA48-L121, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

386. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018461 (Klebsiella pneumoniae strain Kp_Goe_39795 plasmid pKp_Goe_795-2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

387. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP032174 (Klebsiella pneumoniae strain AR_0160 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

388. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC536683 (Klebsiella pneumoniae MyNCGM084 plasmid pMyNCGM084, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

389. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP048418 (Citrobacter freundii strain CitB plasmid pB_CitB, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

390. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LR025095 (Klebsiella pneumoniae isolate KP9201 plasmid pOXA-48_920, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

391. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP026210 (Citrobacter sp. CFNIH10 plasmid pKPC-2fe2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

392. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC545849 (Escherichia coli Ec-MW04 plasmid pEc-MW04_OXA DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

393. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP042574 (Enterobacter hormaechei strain E5 plasmid pE5_003, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

394. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP042542 (Enterobacter hormaechei strain C4 plasmid pC4_002, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

395. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018315 (Klebsiella pneumoniae strain Kp_Goe_822579 plasmid pKp_Goe_579-3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

396. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP015075 (Escherichia coli strain Ecol_745 plasmid pEC745_OXA48, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

397. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP014298 (Klebsiella pneumoniae strain KP38731 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

398. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP042580 (Enterobacter kobei strain C16 plasmid pC16_002, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

399. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to KU159085 (Klebsiella pneumoniae plasmid pOXAAPSS1, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

400. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to KU159086 (Klebsiella pneumoniae plasmid pOXAAPSS2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

401. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018690 (Klebsiella pneumoniae strain Kp_Goe_149473 plasmid pKp_Goe_473-3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

402. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP031374 (Klebsiella pneumoniae strain KpvST101_OXA-48 plasmid pKpvOXA-48, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

403. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP032193 (Salmonella enterica subsp. enterica serovar Senftenberg strain AR_0127 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

404. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_023027 (Klebsiella pneumoniae strain E71T plasmid, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

405. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP026497 (Klebsiella pneumoniae strain 616 plasmid pKp616_2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

406. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP026188 (Enterobacteriaceae bacterium ENNIH2 plasmid pKPC-ddab, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

407. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP044337 (Enterobacter hormaechei strain AKB48 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

408. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LN864819 (Klebsiella pneumoniae plasmid pKP112, complete sequence, strain KP112) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

409. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018342 (Klebsiella pneumoniae isolate Kp_Goe_154414 plasmid pKp_Goe_414-5, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

410. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP031216 (Escherichia coli strain Es_ST80_L1_NDM_10_2017 plasmid pEsST80_L1_NDM, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

411. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LR025091 (Klebsiella pneumoniae isolate KP980 plasmid pOXA-48_980, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

412. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP038457 (Escherichia coli strain EC-129 plasmid pEC129_4, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

413. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_011641 (Klebsiella pneumoniae plasmid pCTXM360, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

414. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_019344 (Serratia marcescens plasmid R830b, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

415. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP042526 (Citrobacter freundii strain E11 plasmid pE11_002, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

416. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP033880 (Escherichia coli strain 50579417 plasmid p50579417_3_OXA-48, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

417. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP031322 (Escherichia coli strain ST2350 isolate Es_ST2350_SE1_NDM_03_2018 plasmid pEsST2350_SE_NDM, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

418. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to CP052472 (Klebsiella pneumoniae strain C16KP0053 plasmid pC16KP0053-4, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

419. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018700 (Klebsiella pneumoniae strain Kp_Goe_149832 plasmid pKp_Goe_832-3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

420. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LR745044 (Klebsiella pneumoniae isolate Klebsiella pneumoniae kpn154 plasmid pOXA48_Kpn154) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

421. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_021078 (Klebsiella pneumoniae strain Kp002 plasmid pJEG011, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

422. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP042490 (Enterobacter hormaechei strain C15 plasmid pC15_002) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

423. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LT985264 (Escherichia coli strain 717 plasmid RCS51TR717_p, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

424. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_LT985241 (Escherichia coli strain 721 plasmid RCS40_p, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

425. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018712 (Klebsiella pneumoniae strain Kp_Goe_827026 plasmid pKp_Goe_026-3, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

426. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC505604 (Klebsiella pneumoniae A1-1 plasmid pKp1-1 genomic DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

427. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to LC508722 (Klebsiella pneumoniae A2-1 plasmid pA2-4 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

428. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_019889 (Klebsiella pneumoniae strain 601 plasmid pNDM-OM, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

429. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to MT193824 (Escherichia coli strain 19-AB01443 plasmid pOX-48-EC1443, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

430. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_MK088079 (Klebsiella pneumoniae strain 19 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

431. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_MK370728 (Klebsiella pneumoniae strain 69G1 plasmid pLimOXA-48, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

432. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP030135 (Klebsiella pneumoniae strain 160111 plasmid pOXA48_L111, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

433. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP042568 (Enterobacter hormaechei strain C44 plasmid pC44_002, complete sequence) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

434. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NZ_CP018736 (Klebsiella pneumoniae strain Kp_Goe_121641 plasmid pKp_Goe_641-2) position: , mismatch: 8, identity: 0.75

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
ggcacgattggactcggccgcggcgaaacccg	Protospacer
.********** ********* ***.. *  *

435. spacer 9.1|1926283|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP032676 (Rhodococcus rhodochrous strain ATCC BAA870 plasmid pNit, complete sequence) position: , mismatch: 8, identity: 0.758

ccgcacaccgacatcgagggccgctacctgatc	CRISPR spacer
ccgcacgccgacttcgagggccgcacctacatt	Protospacer
******.***** ***********  *.  **.

436. spacer 8.1|1923737|33|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_HG938354 (Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence) position: , mismatch: 9, identity: 0.727

ccgcccatgacgatcgcctcgtctcgcgcacat	CRISPR spacer
ccgaccacgacgatcgcctcgtctgggtgaacc	Protospacer
*** ***.**************** *   *  .

437. spacer 8.3|1923859|34|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

gctgggcctggacctgatccgcctgcaccgcacc	CRISPR spacer
cgatgtcctggacctgaacagcctgcaccgcgac	Protospacer
    * *********** * ***********. *

438. spacer 8.6|1923799|32|NZ_CP006850|PILER-CR matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 9, identity: 0.719

gcagcgcggtcagcgtcaggtcatgatcgagc	CRISPR spacer
cgttcgcggtcagcgtcatgccatgatgcagg	Protospacer
    ************** *.******  **

439. spacer 8.7|1923860|33|NZ_CP006850|PILER-CR matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

ctgggcctggacctgatccgcctgcaccgcacc	CRISPR spacer
actcacttcgacctgatgcgcctgcgccgcacc	Protospacer
 .  .*.* ******** *******.*******

440. spacer 8.1|1923737|33|NZ_CP006850|CRISPRCasFinder,CRT matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 10, identity: 0.697

ccgcccatgacgatcgcctcgtctcgcgcacat	CRISPR spacer
ttctcgatgacgatcgccacgtcgcgcgcatgg	Protospacer
.. .* ************ **** ******..

441. spacer 8.3|1923859|34|NZ_CP006850|CRISPRCasFinder,CRT matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

gctgggcctggacctgatccgcctgcaccgcacc	CRISPR spacer
cactcacttcgacctgatgcgcctgcgccgcacc	Protospacer
  .  .*.* ******** *******.*******

442. spacer 8.8|1923922|32|NZ_CP006850|PILER-CR matches to NC_048788 (Mycobacterium phage ThetaBob, complete genome) position: , mismatch: 10, identity: 0.688

agcacgattggcctcggccgctgcgggtcggg	CRISPR spacer
tatctgattggcctgggcggctgcgggttcga	Protospacer
 .. .********* *** *********. *.

443. spacer 9.4|1926466|31|NZ_CP006850|CRISPRCasFinder,CRT,PILER-CR matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 10, identity: 0.677

cgaacgaaagcgattccgcgcgcgcactgtc	CRISPR spacer
gcttcgaattcgattccgcgcgcgcacaact	Protospacer
    ****  ***************** ...

444. spacer 11.1|3213557|36|NZ_CP006850|CRISPRCasFinder matches to NZ_AP014707 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_3p, complete sequence) position: , mismatch: 11, identity: 0.694

aattcgccgccgtgctcacgggcggcctcggccagc	CRISPR spacer
tgcaagccgtcgtgctcgcgggcggcctcggcgctg	Protospacer
 ..  ****.*******.**************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

195660 : 203521

Saccharomonospora_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025346528.1\|195660_196521_+	helix-turn-helix domain-containing protein	I4AZQ1	Saccharomonospora_phage	5.5e-21	32.0
WP_025346529.1\|196567_197026_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_025346530.1\|197112_198588_+	MFS transporter	A0A0M3UL24	Mycobacterium_phage	2.6e-55	35.0
WP_025346531.1\|198673_199231_-	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	H9NC63	Sphingomonas_phage	1.3e-15	37.8
WP_025346532.1\|199232_200144_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	5.0e-89	55.7
WP_025346533.1\|200378_201395_+	alpha/beta hydrolase	J3IZC7	Acanthamoeba_polyphaga_lentillevirus	6.7e-18	26.5
WP_025346534.1\|201516_202224_-	hypothetical protein	NA	NA	NA	NA
WP_025346535.1\|202519_203521_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	6.7e-71	43.6

DBSCAN-SWA_2

1958344 : 1986306

Gordonia_phage(57.89%)

head,capsid,tail,integrase,protease,terminase,portal

attL 1951098:1951113|attR 1983099:1983114

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1951098:1951113	attL	NA	NA	NA	NA
WP_148306769.1\|1958344_1959562_+\|integrase	site-specific integrase	A0A2K9VH95	Gordonia_phage	7.9e-66	39.1
WP_148306770.1\|1959745_1960111_+	hypothetical protein	NA	NA	NA	NA
WP_025348056.1\|1960051_1960345_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_148306771.1\|1960475_1960703_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_025348057.1\|1960699_1960972_+	helix-turn-helix domain-containing protein	A0A1X9SHG1	Mycobacterium_phage	2.8e-08	40.0
WP_025348058.1\|1961087_1961282_+	hypothetical protein	NA	NA	NA	NA
WP_025348059.1\|1961278_1961551_+	hypothetical protein	NA	NA	NA	NA
WP_025348060.1\|1961547_1961841_+	hypothetical protein	NA	NA	NA	NA
WP_025348061.1\|1961833_1962031_+	hypothetical protein	NA	NA	NA	NA
WP_025348062.1\|1962027_1962339_+	hypothetical protein	NA	NA	NA	NA
WP_025348063.1\|1962442_1962712_+	hypothetical protein	NA	NA	NA	NA
WP_025348064.1\|1962708_1963686_+	phage Gp37/Gp68 family protein	A0A1B3B1W9	Gordonia_phage	2.2e-82	48.9
WP_148306772.1\|1963682_1964069_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148306773.1\|1964412_1965192_+	hypothetical protein	NA	NA	NA	NA
WP_025348067.1\|1965191_1965542_+	hypothetical protein	NA	NA	NA	NA
WP_025348068.1\|1965538_1965805_+	hypothetical protein	NA	NA	NA	NA
WP_025348069.1\|1965801_1966011_+	hypothetical protein	NA	NA	NA	NA
WP_025348070.1\|1966003_1966456_+	hypothetical protein	NA	NA	NA	NA
WP_025348071.1\|1966448_1967057_+	hypothetical protein	A0A159B6S5	Tsukamurella_phage	1.6e-11	69.8
WP_025348072.1\|1967049_1967304_+	hypothetical protein	NA	NA	NA	NA
WP_025348073.1\|1967300_1967633_+	hypothetical protein	NA	NA	NA	NA
WP_158436173.1\|1967625_1967778_+	hypothetical protein	NA	NA	NA	NA
WP_025348074.1\|1967774_1968203_+	hypothetical protein	NA	NA	NA	NA
WP_025348075.1\|1968199_1968514_+	hypothetical protein	NA	NA	NA	NA
WP_025348076.1\|1968510_1969176_+	hypothetical protein	H6WSK2	Mycobacterium_phage	1.2e-44	48.5
WP_148306774.1\|1969740_1969944_+	hypothetical protein	NA	NA	NA	NA
WP_025348078.1\|1970074_1970266_+	hypothetical protein	NA	NA	NA	NA
WP_081769172.1\|1970268_1970607_+	HNH endonuclease	H9YSB8	environmental_Halophage	6.2e-05	48.4
WP_025348080.1\|1970726_1971209_+\|terminase	phage terminase small subunit P27 family	A0A1B3B1V2	Gordonia_phage	9.7e-52	68.9
WP_025348081.1\|1971189_1972938_+\|terminase	terminase large subunit	A0A1B3AYP7	Gordonia_phage	1.2e-248	74.3
WP_158436175.1\|1972985_1973150_+	hypothetical protein	A0A222ZEQ3	Arthrobacter_phage	4.6e-06	45.5
WP_025348082.1\|1973149_1974430_+\|portal	phage portal protein	A0A142K7D9	Mycobacterium_phage	7.8e-165	66.7
WP_025348083.1\|1974426_1975218_+\|head,protease	HK97 family phage prohead protease	A0A1U9WRZ1	Gordonia_phage	4.6e-67	60.4
WP_038550376.1\|1975246_1976563_+\|capsid	phage major capsid protein	W0LJX9	Mycobacterium_phage	4.7e-141	63.4
WP_148306775.1\|1976631_1976829_+	hypothetical protein	NA	NA	NA	NA
WP_025348086.1\|1976825_1977368_+	hypothetical protein	A0A2H4P9V1	Gordonia_phage	1.5e-24	41.7
WP_025348087.1\|1977364_1977670_+	hypothetical protein	A0A2H4P9W7	Gordonia_phage	2.6e-18	46.5
WP_025348088.1\|1977672_1977924_+	hypothetical protein	A0A1C9EHQ0	Gordonia_phage	8.4e-07	42.7
WP_025348089.1\|1977920_1978325_+	hypothetical protein	A0A2H4PA61	Gordonia_phage	1.1e-16	44.5
WP_025348090.1\|1978345_1978663_+	hypothetical protein	NA	NA	NA	NA
WP_025348091.1\|1978668_1979208_+	hypothetical protein	A0A023ZYD0	Mycobacterium_phage	5.3e-22	35.8
WP_025348092.1\|1979309_1979696_+	hypothetical protein	NA	NA	NA	NA
WP_025348093.1\|1979725_1980166_+	hypothetical protein	NA	NA	NA	NA
WP_025348094.1\|1980155_1983770_+\|tail	phage tail tape measure protein	A0A142K8Q7	Gordonia_phage	1.2e-66	30.9
1983099:1983114	attR	NA	NA	NA	NA
WP_025348095.1\|1983766_1984663_+	hypothetical protein	NA	NA	NA	NA
WP_081769660.1\|1984698_1986306_+\|tail	phage tail protein	A0A166Y911	Gordonia_phage	1.3e-113	41.0

DBSCAN-SWA_3

2145400 : 2155333

Bacillus_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025348244.1\|2145400_2146243_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	5.1e-80	55.1
WP_025348245.1\|2146252_2146855_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_025348246.1\|2147079_2147646_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	5.4e-09	36.3
WP_025348247.1\|2147806_2147929_+	50S ribosomal protein L36	NA	NA	NA	NA
WP_025348248.1\|2148464_2148698_+	redoxin NrdH	V5UN81	Mycobacterium_phage	1.7e-22	63.6
WP_051494661.1\|2148740_2149244_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A217ER62	Bacillus_phage	2.1e-09	29.5
WP_193365200.1\|2149195_2151385_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	V9VI16	Lactococcus_phage	7.5e-208	51.5
WP_025348251.1\|2151505_2151757_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_025348252.1\|2151753_2152173_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_038552522.1\|2152768_2154091_+	magnesium transporter	NA	NA	NA	NA
WP_025348254.1\|2154370_2155333_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A0N7CCA3	Skermania_phage	1.6e-162	89.4

DBSCAN-SWA_4

6513303 : 6519202

Mycobacterium_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025352130.1\|6513303_6513609_+	glutaredoxin family protein	G9FGZ9	Rhodococcus_phage	8.7e-22	53.1
WP_025352131.1\|6513601_6514243_+	hypothetical protein	A0A249XTW9	Mycobacterium_phage	1.3e-35	42.6
WP_148307002.1\|6514235_6514640_+	hypothetical protein	NA	NA	NA	NA
WP_148307003.1\|6514632_6515241_+	hypothetical protein	NA	NA	NA	NA
WP_025352134.1\|6515233_6515791_+	3'-5' exoribonuclease	A0A249XQ39	Mycobacterium_phage	1.9e-59	61.0
WP_081769509.1\|6515787_6516270_+	DUF2493 domain-containing protein	A0A1I9SDK9	Streptomyces_phage	2.0e-12	39.0
WP_025352136.1\|6516266_6517022_+	hypothetical protein	A0A142K9M4	Gordonia_phage	2.5e-09	42.0
WP_025352137.1\|6517014_6517863_+	hypothetical protein	NA	NA	NA	NA
WP_148307004.1\|6517855_6518494_+	hypothetical protein	NA	NA	NA	NA
WP_025352139.1\|6518490_6518859_+	hypothetical protein	A0A191SAX1	Nostoc_phage	1.8e-05	38.8
WP_025352140.1\|6518851_6519202_+	HIT domain-containing protein	G8I9U4	Mycobacterium_virus	3.7e-16	44.6

DBSCAN-SWA_5

6524070 : 6535969

Mycobacterium_phage(30.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148307007.1\|6524070_6524544_+	DUF4326 domain-containing protein	A0A142KCP7	Gordonia_phage	7.6e-17	41.3
WP_158436384.1\|6524695_6524851_+	hypothetical protein	NA	NA	NA	NA
WP_148307008.1\|6524904_6525231_+	hypothetical protein	A0A088F7U7	Mycobacterium_phage	6.9e-09	34.3
WP_025352154.1\|6525227_6525707_+	hypothetical protein	NA	NA	NA	NA
WP_148307009.1\|6525767_6526097_+	hypothetical protein	NA	NA	NA	NA
WP_025352156.1\|6526093_6526459_+	hypothetical protein	NA	NA	NA	NA
WP_025352157.1\|6526963_6528526_+	TROVE domain-containing protein	A0A1J0GW83	Streptomyces_phage	3.3e-117	45.5
WP_025352158.1\|6528525_6529704_+	RtcB family protein	G8I4I6	Mycobacterium_phage	7.7e-151	67.2
WP_025352159.1\|6529708_6530395_+	nucleotidyltransferase domain-containing protein	A0A1J0GW18	Streptomyces_phage	6.9e-35	41.0
WP_025352160.1\|6530391_6530994_+	metallophosphoesterase	A0A142F2L8	Mycobacterium_phage	2.4e-39	45.4
WP_148307010.1\|6531473_6532619_+	hypothetical protein	NA	NA	NA	NA
WP_025352162.1\|6532611_6533055_+	hypothetical protein	NA	NA	NA	NA
WP_025352163.1\|6533119_6533779_+	hypothetical protein	G9FH23	Rhodococcus_phage	1.2e-39	49.4
WP_025352164.1\|6533895_6534102_+	hypothetical protein	G9FH24	Rhodococcus_phage	2.2e-13	55.9
WP_025352165.1\|6534288_6534534_+	hypothetical protein	G1DUC7	Mycobacterium_virus	1.8e-14	48.8
WP_025352166.1\|6534785_6535079_+	hypothetical protein	NA	NA	NA	NA
WP_025352167.1\|6535202_6535466_+	hypothetical protein	NA	NA	NA	NA
WP_025352168.1\|6535465_6535969_+	hypothetical protein	A0A1B3AYB9	Gordonia_phage	1.5e-07	38.4

DBSCAN-SWA_6

6541454 : 6553283

Mycobacterium_phage(50.0%)

portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025352178.1\|6541454_6541703_+	hypothetical protein	A0A1P8DUC6	Mycobacterium_phage	8.3e-15	49.3
WP_025352179.1\|6541821_6542856_+	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_025352180.1\|6542852_6543488_+	glycosyltransferase	A0A1P8DUC9	Mycobacterium_phage	2.5e-47	48.6
WP_025352181.1\|6543525_6543801_+	hypothetical protein	A0A1C9EI77	Rhodococcus_phage	6.4e-08	49.2
WP_158436386.1\|6543862_6544021_+	hypothetical protein	NA	NA	NA	NA
WP_158436388.1\|6544017_6544179_+	hypothetical protein	NA	NA	NA	NA
WP_025352182.1\|6544178_6544592_+	HNH endonuclease	Q8SBD7	Shigella_phage	1.3e-12	40.2
WP_038555212.1\|6544845_6545373_+	hypothetical protein	Q6VY59	Streptomyces_phage	1.7e-33	50.0
WP_081769803.1\|6545631_6545904_+	hypothetical protein	A0A0K0N6I0	Gordonia_phage	1.1e-07	39.8
WP_025352185.1\|6545911_6547558_+	hypothetical protein	A0A142K6H6	Mycobacterium_phage	7.4e-200	61.2
WP_025352186.1\|6547576_6548998_+\|portal	phage portal protein	A5YJX1	Mycobacterium_phage	1.2e-129	54.3
WP_025352187.1\|6548978_6549929_+	hypothetical protein	A0A249XMM5	Mycobacterium_phage	9.2e-46	37.9
WP_148307013.1\|6550002_6550671_+	hypothetical protein	NA	NA	NA	NA
WP_025352189.1\|6550682_6551504_+	hypothetical protein	Q855K4	Mycobacterium_virus	2.3e-101	68.1
WP_025352190.1\|6551505_6552084_+	hypothetical protein	A0A2P1CI81	Actinomyces_phage	1.3e-29	43.5
WP_025352191.1\|6552092_6552422_+	hypothetical protein	NA	NA	NA	NA
WP_025352192.1\|6552423_6552732_+	hypothetical protein	NA	NA	NA	NA
WP_025352193.1\|6552728_6553283_+	hypothetical protein	A0A097EWD5	Mycobacterium_phage	4.4e-16	31.8

DBSCAN-SWA_7

7979530 : 8006779

uncultured_Caudovirales_phage(33.33%)

portal,capsid,terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025353356.1\|7979530_7980298_+	phage antirepressor N-terminal domain-containing protein	A0A1B3AYU1	Gordonia_phage	1.5e-94	68.7
WP_025353357.1\|7980371_7981217_+	hypothetical protein	NA	NA	NA	NA
WP_025353358.1\|7981213_7981474_+	hypothetical protein	NA	NA	NA	NA
WP_025353359.1\|7981470_7981812_+	hypothetical protein	NA	NA	NA	NA
WP_025353360.1\|7981808_7982045_+	hypothetical protein	NA	NA	NA	NA
WP_025353361.1\|7982041_7982827_+	hypothetical protein	A0A173G9J5	Propionibacterium_phage	3.7e-56	50.2
WP_025353362.1\|7982823_7984134_+	AAA family ATPase	A0A2H4J7B1	uncultured_Caudovirales_phage	1.6e-117	50.0
WP_025353363.1\|7984161_7984443_+	hypothetical protein	NA	NA	NA	NA
WP_025353364.1\|7984546_7985212_+	hypothetical protein	A0A142K7R6	Mycobacterium_phage	2.4e-40	47.4
WP_158436426.1\|7985208_7985364_+	hypothetical protein	NA	NA	NA	NA
WP_025353365.1\|7985424_7985664_-	hypothetical protein	NA	NA	NA	NA
WP_158436428.1\|7986152_7986302_+	hypothetical protein	NA	NA	NA	NA
WP_025353366.1\|7986301_7986565_+	hypothetical protein	NA	NA	NA	NA
WP_025353367.1\|7986569_7986851_+	HNH endonuclease	A0A2H4J9P9	uncultured_Caudovirales_phage	1.2e-22	53.3
WP_025353368.1\|7986980_7987301_+	hypothetical protein	A0A2H4IZP1	uncultured_Caudovirales_phage	6.7e-17	63.6
WP_051494888.1\|7987332_7988748_+\|terminase	terminase	A0A142KAW2	Gordonia_phage	3.0e-149	58.7
WP_051495216.1\|7988756_7990223_+\|portal	phage portal protein	A0A2H4J2P6	uncultured_Caudovirales_phage	2.2e-155	62.3
WP_025353371.1\|7990219_7991089_+	hypothetical protein	A0A2P1A0Q1	Gordonia_phage	2.5e-53	44.1
WP_025353372.1\|7991139_7991715_+	hypothetical protein	A0A142KAW5	Gordonia_phage	5.1e-07	68.6
WP_025353373.1\|7991730_7992651_+\|capsid	phage major capsid protein	A0A2H4IYA3	uncultured_Caudovirales_phage	4.3e-125	72.8
WP_025353374.1\|7992650_7992896_+	hypothetical protein	NA	NA	NA	NA
WP_025353375.1\|7992902_7993364_+	hypothetical protein	A0A2H4IYA5	uncultured_Caudovirales_phage	3.7e-32	52.1
WP_025353376.1\|7993356_7993722_+	hypothetical protein	A0A2D1G9N7	Mycobacterium_phage	4.1e-26	52.5
WP_025353377.1\|7993718_7993937_+	hypothetical protein	NA	NA	NA	NA
WP_025353378.1\|7993926_7994193_+	hypothetical protein	NA	NA	NA	NA
WP_148307078.1\|7994185_7994590_+	hypothetical protein	NA	NA	NA	NA
WP_025353380.1\|7994656_7995472_+	IPT/TIG domain-containing protein	A0A222ZEQ0	Arthrobacter_phage	3.6e-30	34.4
WP_025353381.1\|7995567_7995882_+	hypothetical protein	NA	NA	NA	NA
WP_025353382.1\|7995944_7996127_+	hypothetical protein	NA	NA	NA	NA
WP_025353383.1\|7996137_7999446_+\|tail	phage tail tape measure protein	E0YQ16	Mycobacterium_phage	2.2e-62	45.2
WP_025353384.1\|7999447_8000404_+	hypothetical protein	A0A2H4JHX7	uncultured_Caudovirales_phage	4.9e-47	38.0
WP_025353385.1\|8000403_8002098_+	hypothetical protein	G1BSP2	Mycobacterium_virus	4.2e-134	44.3
WP_025353386.1\|8002120_8002801_+	translation initiation factor IF-2 N-terminal domain-containing protein	A0A2D1G9P8	Mycobacterium_phage	2.9e-17	40.4
WP_025353387.1\|8002804_8003608_+	N-acetylmuramoyl-L-alanine amidase	F1B2S6	Tsukamurella_phage	3.9e-53	59.2
WP_025353388.1\|8003604_8003799_+	hypothetical protein	D4P732	Rhodococcus_phage	3.7e-10	52.5
WP_148307079.1\|8003801_8004188_+	hypothetical protein	NA	NA	NA	NA
WP_025353390.1\|8004184_8004838_+	hypothetical protein	NA	NA	NA	NA
WP_025353391.1\|8004834_8005176_+	hypothetical protein	NA	NA	NA	NA
WP_025353392.1\|8005172_8006414_+	hypothetical protein	NA	NA	NA	NA
WP_025353393.1\|8006434_8006779_+	hypothetical protein	W8EKC3	Mycobacterium_phage	1.5e-06	41.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP006850

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection