CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP004081	Enterococcus faecalis DENG1 chromosome, complete genome	2 crisprs	csa3,cas3,cas14j,DinG,DEDDh	0	5	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP004081_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004081_1

1934283-1934648

Orphan

II-A,II-B

Consensus_repeat	Method
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRISPRCasFinder
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRT

5 spacers

The CRISPR arrays of NZ_CP004081_1

>merge|NZ_CP004081|1|1934283-1934648|CRISPRCasFinder,PILER-CR,CRT
GTGATAGTTTGTTTTTTAACAACATGGCTATAAAACAGGGGAGAAAAAGCCAAATCAAAAAAGTTTGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTATAACGTAAATCACAGTCTTTTGTAAGTCGTTTTGGTACCATTCCAAACAACATGACTCTAAAACTGGTCGCAGTTTCCGCTCGAACTGCTTTTCGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTATGGTTTTGAATAAATTGTACATCATTATGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGTCTTTAAAGTAACCAGTAACATAATAACCGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP004081|1|1|1934283-1934648|CRISPRCasFinder
GTGATAGTTTGTTTTTTAACAACATGGCTATAAAAC	AGGGGAGAAAAAGCCAAATCAAAAAAGTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATAACGTAAATCACAGTCTTTTGTAAGTC
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	TGGTCGCAGTTTCCGCTCGAACTGCTTTTC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATGGTTTTGAATAAATTGTACATCATTAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GTCTTTAAAGTAACCAGTAACATAATAACC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP004081|1|1|1934349-1934648|PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATAACGTAAATCACAGTCTTTTGTAAGTC
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	TGGTCGCAGTTTCCGCTCGAACTGCTTTTC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATGGTTTTGAATAAATTGTACATCATTAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GTCTTTAAAGTAACCAGTAACATAATAACC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP004081|1|1|1934349-1934648|CRT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATAACGTAAATCACAGTCTTTTGTAAGTC
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	TGGTCGCAGTTTCCGCTCGAACTGCTTTTC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATGGTTTTGAATAAATTGTACATCATTAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GTCTTTAAAGTAACCAGTAACATAATAACC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004081.1\|WP_002388226.1\|1942842_1943988_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP004081.1\|WP_024797018.1\|1927946_1929713_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_CP004081.1\|WP_002362065.1\|1921882_1924306_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NZ_CP004081.1\|WP_002356966.1\|1937965_1938331_-\|DUF1033-family-protein	unknown	unknown	gnl\|CDD\|336361
NZ_CP004081.1\|WP_002388223.1\|1934805_1935669_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP004081.1\|WP_002360016.1\|1925859_1926765_-\|prenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_CP004081.1\|WP_002364252.1\|1938428_1938998_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP004081.1\|WP_002360015.1\|1926886_1927867_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NZ_CP004081.1\|WP_002356959.1\|1942430_1942775_-\|DUF1831-domain-containing-protein	unknown	unknown	gnl\|CDD\|370163
NZ_CP004081.1\|WP_002360017.1\|1924619_1925831_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP004081.1\|WP_002364244.1\|1921050_1921752_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP004081.1\|WP_002356974.1\|1932457_1933876_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP004081.1\|WP_002364247.1\|1929709_1931443_-\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|274323
NZ_CP004081.1\|WP_002384339.1\|1920183_1920933_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP004081.1\|WP_002392265.1\|1935753_1938003_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_CP004081.1\|WP_002362074.1\|1939662_1940901_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP004081.1\|WP_002362076.1\|1944144_1945119_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039
NZ_CP004081.1\|WP_024797017.1\|1931447_1932461_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
NZ_CP004081.1\|WP_002362073.1\|1939130_1939646_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_CP004081.1\|WP_002362075.1\|1941080_1942205_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664

Protein	Function_ID	Function_description	E-value
NZ_CP004081.1\|WP_002388226.1\|1942842_1943988_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	4.96895e-180
NZ_CP004081.1\|WP_024797018.1\|1927946_1929713_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NZ_CP004081.1\|WP_002362065.1\|1921882_1924306_-\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.48202e-174
NZ_CP004081.1\|WP_002356966.1\|1937965_1938331_-\|DUF1033-family-protein	gnl\|CDD\|336361	pfam06279, DUF1033, Protein of unknown function (DUF1033). This family consists of several hypothetical bacterial proteins. Many of the sequences in this family are annotated as putative DNA binding proteins but the function of this family is unknown.	4.62165e-64
NZ_CP004081.1\|WP_002388223.1\|1934805_1935669_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	3.31428e-27
NZ_CP004081.1\|WP_002360016.1\|1925859_1926765_-\|prenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	8.82053e-105
NZ_CP004081.1\|WP_002364252.1\|1938428_1938998_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	3.60546e-15
NZ_CP004081.1\|WP_002360015.1\|1926886_1927867_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.52576e-80
NZ_CP004081.1\|WP_002356959.1\|1942430_1942775_-\|DUF1831-domain-containing-protein	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.33245e-53
NZ_CP004081.1\|WP_002360017.1\|1924619_1925831_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	1.24993e-121
NZ_CP004081.1\|WP_002364244.1\|1921050_1921752_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.52313e-37
NZ_CP004081.1\|WP_002356974.1\|1932457_1933876_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NZ_CP004081.1\|WP_002364247.1\|1929709_1931443_-\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|274323	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit. The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD.	0
NZ_CP004081.1\|WP_002384339.1\|1920183_1920933_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	3.18476e-110
NZ_CP004081.1\|WP_002392265.1\|1935753_1938003_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP004081.1\|WP_002362074.1\|1939662_1940901_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.51661e-174
NZ_CP004081.1\|WP_002362076.1\|1944144_1945119_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
NZ_CP004081.1\|WP_024797017.1\|1931447_1932461_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	1.3236e-102
NZ_CP004081.1\|WP_002362073.1\|1939130_1939646_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	1.1162e-31
NZ_CP004081.1\|WP_002362075.1\|1941080_1942205_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0

>NZ_CP004081.1|WP_002356974.1|1932457_1933876_-|cytochrome-ubiquinol-oxidase-subunit-I
MFDIVTLARIQFAMTTVFHFFFVPFSIGLALVVAIMETMYVVKKEERYRKMAKFWGNIFLLSFAVGVVTGIIQEFQFGMNWSDYSRFVGDIFGAPLAVEALLAFFLESTFLGLWIFTWDKMNPKVHVTFIWLVVFGSMMSAFWILVANSFMQHPVGYVINNGRAEMVDFVAVISNPKVWYEFSHVIMGAFTLGGMAVAGMAAFQLLKKRDISFHKASMRIGLWVTLFGSIGVLLAGDLQMKALIEGQPMKFAAMEGAYEDSDDPAAWTLIAWADEREHKQVFGIDIPYMLSILSYNKLSGSVDGMDTVNKRLVEKYGDDKNYYPPVNTLFWSFRIMAGFGALMLLVAALGLFFTRKKKPSLYEKKWMLWIVALCTFAPFLANTTGWLVTELGRYPWTVYGLFTIEQSVSPNVSVASLITSNVIYFLLFAGLGSVMVYLVILELRKGPDYEAKKLAKENEPALDPFDKGVFGE
>NZ_CP004081.1|WP_024797017.1|1931447_1932461_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MSTLQLLWFVLIGVLFSGFFFLEGFDFGVGMAVQTLAHNDDEKDQVVATIGPVWDGNEVWLLTAGGAMFASFPYWYASLFSGYYLILFTILFGLIIRGVSFEFRHNMPEGKRRRMWNWTLSIGSFLVPFFFGILFISLVQGMPLDANGNMHAQFTDYFNLFSIVGGVVLTLLCYLHGMNYIALKTEGPIRERARNYAEILYGVLYVGLVVFAVLMYFKTDFYEKNFAVTLILTLAIVVLTVIANVGVFKRKEMLAFLASGLTLVVLVALLFSGLFPRVMIGSEGFDLLIKDATSTPYTLKIMTWISLSILPFVLAYTAWSYYIFRKRISQTAVPEGY
>NZ_CP004081.1|WP_002364247.1|1929709_1931443_-|thiol-reductant-ABC-exporter-subunit-CydD
MIDKDILQMPKIKKILVLLAGFSFLQAVFIIGQAFFLSKAIVGLWSGGHLNQQLQSILLFFIFYLGRHVITYFRERMLDTFSYERSKELREQLLTKIFRLGPNVVQKNGTGNMVTMALEGISQTENYLQLILTKMMNMMIIPWIILAFVFTQDIRSGVTLLIVFPIIIIFMIVLGYAAQSKADKQYAAFQMLSNHFIDSLRGIDTLKLFGLSKKYAGSIYHTSERFRKATMSTLKIAILSTFALDFFTTLSVAVVAVFLGLSLLNGTILLFPALVTLILAPEFFLPIRDFSSDYHATLDGKNSFQAIQAVLALPEAEQTDVLTLDDWHQESQLSVTALNFSYEDATQEAIQSLQFSVDGRKKIGIIGASGSGKSTLINLLSGFLLPTEETSQLAINGQTIPHFLQKDWQKQILYIPQAPYIFQDTLANNIRFYTPEATDEAIQQAIQLVGLDELVKDLPEGIQTLIGESGRMLSGGQAQRVALARAFVDQKRHVLLFDEPTAHLDIETEVEMKERMLPLMNNHLVFFATHRLHWMEEMDYILVMEKGQLVEQGTLAELIEKDGYYVQLMKQMRGGRQ
>NZ_CP004081.1|WP_024797018.1|1927946_1929713_-|thiol-reductant-ABC-exporter-subunit-CydC
MMEKQPTTKDVWKNDQWVRPFLKRYKKTLYFALLLGFLTFFSAGALMFTSGYLISRAASLPENILLIYIPIVLTRAFGIGRPVFRYVERLTSHNWVLKMTSDLRLKLYNVLEKDAIFFKTKYRTGDILGLLSEDINHIQNLYLRTIFPTVIAWILYIFLVIALGFFSWWFALCMLLMLGVVVFLLPLVSVLVNGARQEKHKYAKNELYQTLTDNILGVSDWVFSQRGSEFVARYETDEANVRALDEKMKQFNRGRDFVLQLLFGVIAIAILAWTSVRFPGNHGGAANWIGAFVLTVFPLIDAFAPLPAAAQETTIYKDSIRRFNELPEGEDDSTEAPVQPNGTSLSIEHLSFAYENQEKKVLNDLSLTIPEKQKLAILGRSGSGKSTLASLIRGDLRPTSGEILLGNIPTEAFGETMTEYIGVMHQAPYLFRTTILNNIRIGREEASEAEVWAVLEKVGLKEMVAQLPEGLQTMVDEAGLRFSGGERHRLALARILLQDTPIVLLDEPTTGLDPITEQQLLETFFEALKDKTVIWITHHLQGVTLMDQVIFIEDGQLEMSGTPEELLATNAHYQKLYRIDRGISSFEE
>NZ_CP004081.1|WP_002360015.1|1926886_1927867_+|polyprenyl-synthetase-family-protein
MNTFWKSFPDVERSLTETCELIEQTLHTRNEDIEEALVTLARSGGKLLRPAFFFLFAQLGDEEKQEKQQLLKIAASLEILHMATLIHDDIIDDSPLRRGAVTIQSQYGKDVAVYTGDLLFTEFFTLIADAMNGSEFMKINAQGMKRLLLGELDQMSHRFDRRMSIPAYLRSVNGKTAELFSLSCLEGAYFGHSSKEVQRLAKRIGRHIGIAFQVYDDILDYTADTETLKKPALEDLSQGVYTLPLLFAYQAAPDVFSPYLDKGRAITLEEAAEVAALVNDYHGVTEAQAFAKKVTNKAITDIQQLPDGTAKETLLSLTELLLHRSF
>NZ_CP004081.1|WP_002360016.1|1925859_1926765_-|prenyltransferase
MNREIFFELVELKAKTASVLPFLLGICFSWYQYGRLHVGYVLIFFIAMFIFNMAVDILDNYNDYHHATEVHDYKEKTNIIGRENLSLPLIRKMIFWMILVSALMGIGLSFIVGWPLLIMGLYCYLIGIFYSSGPKPLSSLPLGEVFSGFTMGFMITLICVYINTFEVFNWSAANLWGIFLVALPNTCYIANLMLANNICDLEEDENNKRYTLVHYLGKASSLKLFVGLNTIAMLAILLAVGLGLTPPTMLLMLLTLPFVRKQTQALLKEQVKSKTFVCAVKILAVGATAQVLFFAIGLWWL
>NZ_CP004081.1|WP_002360017.1|1924619_1925831_-|NAD(P)/FAD-dependent-oxidoreductase
MNKKHVVILGAGYAGLKTLRELQKGAKDVEITLVDRNNYHYEATDLHEVAAGTQPAEKITYNIMDVVDEKMTTFIQGTVKTIDAATQTVALEDGQTINYDYLVVSLGFESESFGIPGVQEHALQMVDVKTALNVYEHIQEQMRQYKATQNEEFLKIVVCGAGFTGIELLGSLVENKPKFAEIAGVSADQIQIYCVEAVTRLLPMFNEKLANYGVQLLKDSAIHLLLGKPIKEIKPGAVVYQDNEAGDLAELSAKTIIWTTGVSGSHVVGDSGFEARRGRVMVQPDLTDANHSNVYIIGDCSAVMDTETNRPYPTTAQIALKMGAHAAKNIQAQLKGEATKPFSFKSQGSVCSVGNTRALGIVGKTDIKGYPASFMKKIIMNKALFETGGTKEMMAKGRFDLYH
>NZ_CP004081.1|WP_002362065.1|1921882_1924306_-|DNA-translocase-FtsK
MAQKRSTNKKKSTTKKKTKKQQQQQERLNYMFLGLIFILFGVFGLFRLGFLGTLLANCLRLVVGNTFPFAAILLILYGLLVMIYGKDFPLKRGRPIFGAVLIYISVLLFFHAFMFRNVSGSQPDILGNTWEFLQSDLKANQVTQNVGGGMIGALLYQGTYFLVAQFGSYLIATLLLLAGIFLMSMWDFQQIVDHFQSIQDRLSHVSAKSQARQEEKEAKRAAKKEAKAAERQAKIEAAAQQKLQERERMEQAAADRLTKTPVETHQPMVEEPAAPTPVQIDSFQQQNQAMPVPPIAATKPQREQEEEAADEAGVLEFEISEEAEDRDYQLPPTDLLDTIQATDQSGEYEKIEKNIGVLEQTFKSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNSAISTVSFRDIVEAQPSHPDKLLEVPLGRDISGMVQTADLSKMPHLLIAGSTGSGKSVAINGIITGILMQAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTNPRKAAQALQKVVQEMEFRYEKFAATGVRNITGYNQLIQQKNAEDGENRPILPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDTNGAEKLLGRGDMLFLPMGENKPIRIQGAFISDQEVERVVAFVTDQQEAEYQESMMPTDEPTTSGGGEAPQDELFEEAKNLVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVIGPSEGSKPRKVFLQAESEEAAPETPEQ
>NZ_CP004081.1|WP_002364244.1|1921050_1921752_-|GntR-family-transcriptional-regulator
MRRKSVLYLEVADQIKEDILSGKYPVGTFLPTETELEELFNVSKITIRRAIEMLATEEFVEKKSGRGTTVLSNRPYNKLSKAGTFTEFLNESGQKVTKKVLQVENLTLSKEMPAYQFLGEEVVHLSRLYLIDEQPYIYFNYYLPAAMKDVSLTEYKEESLYRLMDRHAIEIYKFEDRFEVATLTEAEQKMLQTTETTGLKRIRRSLSPTGRCVEYSEAIYNTKIHPYVIEYEA
>NZ_CP004081.1|WP_002384339.1|1920183_1920933_-|ABC-transporter-ATP-binding-protein
MLEVQNLKKVYGNEIKYEALKGINLTVQDGEFIGIMGPSGSGKSTLLNLLATIDSPTDGEILLNGKNPNNLNQEQIAKFRRTELGFVFQSFNLMPTLTVEENIILPLTLDGEKVSVMKRQLAELSERLGINHLLKKRIAEISGGQAQRVAVARAMIHHPQLLLADEPTGNLDTKSSKDVMGLLQQLNEEEAATILMVTHDPLAASYCKRIVFIKDGELIDEIIQNGNQKEFYDLIMVKLAEIEGVDNEF
>NZ_CP004081.1|WP_002388223.1|1934805_1935669_-|AraC-family-transcriptional-regulator
MLANLNQAMDYIEEHLTEEVSFDELAKKTGISVYHFKRTFSFVAGMSLAEYIKKRRLAEANLALLAGEKVTDVAFKYGYQSIEGFSRAFRDWTGQAPSEVMKTQIQKTFPKFSFYIDIKGGQSMDVKLIEKPAFQIVGVSQKVPLQYQGENQAIMELAQRITPQQRAEMHTFDDVYPHQVVNASFDFQEGRTTEGGEMTHMIGFATSQENTYEDLEQLSVPAHTWAVFPNEGPFPQTLQETWARIFSEWLPSSGYQVVAAPEISFTQYQGPAEAKYSEIWLAVTATK
>NZ_CP004081.1|WP_002392265.1|1935753_1938003_-|DNA-topoisomerase-III
MAKQNSANGKLFETHEFKEKPQGIFFKLFFYSRNLEKIELIFGIIRKDSTQKGAKLVVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLTVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
>NZ_CP004081.1|WP_002356966.1|1937965_1938331_-|DUF1033-family-protein
MYQVITMYGDNEPWWFFDDWQEDIVQEKTFDNLTDAETYYVEVWQKLSQNYTYVNTKPNYLTAFWNDGEERWCEECDEDLQQYFGLALLENHHAVTFENKAEFTTISNHFGKTKFCKRKVI
>NZ_CP004081.1|WP_002364252.1|1938428_1938998_-|TetR/AcrR-family-transcriptional-regulator
MAKKRNLTKAKILESARNLAEELGVQQLTFQNLAVDLGIKYPSLYNHFKNIAEVKNALVDLLIQELNDALRRALVGKSGAEAIRIYAETYQQFAFENSAVYELLISVPKTQNQQLIEGIHETNQIILQLLAFYPFNNEERLHKSRELRSLIHGYITLRFLGYFQREEATPEESYRRMIEDFIASLEVAR
>NZ_CP004081.1|WP_002362073.1|1939130_1939646_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MHITNRSHLADRYGKRTSAEFLLHERPILSFPISLAAIPKEARYLSWELIDYDTIPLIGFPFIHWLAANVPVTNEIPEDFSRTALKPTIQGKNSLASPLGKQMIPALATETLPELTERYLGLSPRSGVHTYTLYVYATKNPLNLKEGFFANELHQALNDQRLAKAKFEFLY
>NZ_CP004081.1|WP_002362074.1|1939662_1940901_+|multidrug-efflux-MFS-transporter
MYELIKSKIFRPRQPWEKNLLVLWFGTFMAGIGFSLVMPFMPLYINTLGTFTHQQLNFWSGITFSSTFLVTTIVSPWWGRLADRKGRKLMLLRASLGMAIVISLMGAVTSVYQLIGLRLLQGVFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTLLGPLLGGVTASIFGYRPTFFITGTILLLVFVLSLVFVHEEFVPIEKNQAASGKQILKKLEHPHVILGMFITTLIIQASNNSISPIISLYIQQLLGGHGNVTLISGVIASIPGIATLIAAPRFGRLGDRIGSERILTIGLILAIFVYLPMAFVQNVWQLAMLRFLVGISDACLLPAVQTLITRYSPSDAAGRIFSYNQSFQATGNVIGPMIGSSVSAAFGYRGVFISTSCLVLLNLLWVRRSTAELKKEKNDD
>NZ_CP004081.1|WP_002362075.1|1941080_1942205_-|tRNA-2-thiouridine(34)-synthase-MnmA
MADNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVAKVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRLGRTPNPDVMCNKEIKFKAFLDYAMQLGADYVATGHYAQVETDENGVVHMLRGIDNNKDQTYFLSQLSQAQLAKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGVCFIGEKNFKEFLSNYLPAKKGNMVTEDGEIKGQHDGLMYYTIGQRQGLGIGGGGKTQEPWFVIGKDLTTNTLYVGQGFHHEKLYATHLEASEVHFTVDTPMPKEFDCTAKFRYRQADIPVHVSLSEDGTKATVTFKEPARAVTPGQAVVFYDGMECLGGGLIDRAYQDEKELQYV
>NZ_CP004081.1|WP_002356959.1|1942430_1942775_-|DUF1831-domain-containing-protein
MAFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKPMNIFKNEQHEMSKEKYFFLMDGLISRGVLEKVE
>NZ_CP004081.1|WP_002388226.1|1942842_1943988_-|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQTIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKINGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSAEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHFKGIPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK
>NZ_CP004081.1|WP_002362076.1|1944144_1945119_-|ribose-phosphate-diphosphokinase
MTENYQDDTLRIFSLNANRPLAEKIAASVGTELGKSTVRQFSDGEIQINIEESIRGDHVYIIQATNAPVNDHLMELLILIDALKRASAKTINVILPYYGYARQDRTAKPREPITAKLVANMLVEAGATRLLTLDLHTVQVQGFFDIPVDNLFTMPLFAHYYRQQALVGEEIVIVSPKNSGVQRARSLSEYLDATLAIVDHEEIDGVRQEGYVIGNVAGKKCILVDDILNTGQTLATAAEVLMKNGAQEVYACASHGLLSEGAKATLENAPIKEISITDSVYTTADRQPATLNIISCAELMGEALLRIHENKPMSPLFRLEPKGE

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Crispr_ID: NZ_CP004081_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004081_2

2781548-2781621

Orphan

Consensus_repeat	Method
ATAGTTGGCGAGCAACAGAAAAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP004081_2

>merge|NZ_CP004081|2|2781548-2781621|CRISPRCasFinder
ATAGTTGGCGAGCAACAGAAAAACTCGATATAGAATTGGACGTAGAGCCAATAGTTGGTGAGCAACAGAAAAAC

>NZ_CP004081|2|2|2781548-2781621|CRISPRCasFinder
ATAGTTGGCGAGCAACAGAAAAAC	TCGATATAGAATTGGACGTAGAGCCA
ATAGTTGGTGAGCAACAGAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004081.1\|WP_002381060.1\|2783721_2784693_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP004081.1\|WP_002354867.1\|2788180_2790757_-\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NZ_CP004081.1\|WP_002354866.1\|2790757_2791129_-\|YlbF-family-regulator	unknown	unknown	gnl\|CDD\|226923
NZ_CP004081.1\|WP_002354877.1\|2776888_2777602_-\|trehalose-operon-repressor	unknown	unknown	gnl\|CDD\|274116
NZ_CP004081.1\|WP_002354883.1\|2774489_2774939_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NZ_CP004081.1\|WP_002354871.1\|2784867_2785305_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP004081.1\|WP_002392696.1\|2782522_2782666_-\|putative-holin-like-toxin	unknown	unknown	gnl\|CDD\|319017
NZ_CP004081.1\|WP_002392698.1\|2793925_2794057_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004081.1\|WP_002354863.1\|2792173_2793730_-\|ribonuclease-Y	unknown	unknown	gnl\|CDD\|237177
NZ_CP004081.1\|WP_002375504.1\|2791216_2792014_-\|TIGR00282-family-metallophosphoesterase	unknown	unknown	gnl\|CDD\|379099
NZ_CP004081.1\|WP_002354879.1\|2775779_2776493_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP004081.1\|WP_002406717.1\|2777863_2780608_+\|glycoside-hydrolase-family-65-protein	unknown	unknown	gnl\|CDD\|224471
NZ_CP004081.1\|WP_002354869.1\|2785437_2785992_-\|septum-formation-protein-Maf	unknown	unknown	gnl\|CDD\|238310
NZ_CP004081.1\|WP_002354886.1\|2770681_2771548_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224343
NZ_CP004081.1\|WP_002354885.1\|2771715_2773020_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_CP004081.1\|WP_002354875.1\|2780622_2781273_+\|beta-phosphoglucomutase	unknown	unknown	gnl\|CDD\|213672
NZ_CP004081.1\|WP_002354884.1\|2773012_2774281_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_CP004081.1\|WP_002354880.1\|2774979_2775684_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP004081.1\|WP_002354868.1\|2786016_2788149_-\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|223400
NZ_CP004081.1\|WP_002354887.1\|2770122_2770377_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP004081.1\|WP_002381060.1\|2783721_2784693_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP004081.1\|WP_002354867.1\|2788180_2790757_-\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NZ_CP004081.1\|WP_002354866.1\|2790757_2791129_-\|YlbF-family-regulator	gnl\|CDD\|226923	COG4550, COG4550, Predicted membrane protein [Function unknown].	8.72333e-15
NZ_CP004081.1\|WP_002354877.1\|2776888_2777602_-\|trehalose-operon-repressor	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	6.92052e-137
NZ_CP004081.1\|WP_002354883.1\|2774489_2774939_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	2.8499e-49
NZ_CP004081.1\|WP_002354871.1\|2784867_2785305_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.48715e-93
NZ_CP004081.1\|WP_002392696.1\|2782522_2782666_-\|putative-holin-like-toxin	gnl\|CDD\|319017	pfam16935, Hol_Tox, Putative Holin-like Toxin (Hol-Tox). Hol_Tox is a family of small proteins (34-48aas) with a single TM region. Members can exhibit antibacterial activity against Gram-positive bacteria but not against Gram-negative bacteria.	3.57939e-12
NZ_CP004081.1\|WP_002354863.1\|2792173_2793730_-\|ribonuclease-Y	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0
NZ_CP004081.1\|WP_002375504.1\|2791216_2792014_-\|TIGR00282-family-metallophosphoesterase	gnl\|CDD\|379099	pfam13277, YmdB, YmdB-like protein. This family of putative phosphoesterases contains the B. subtilis protein YmdB.	3.56401e-154
NZ_CP004081.1\|WP_002354879.1\|2775779_2776493_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	5.58773e-17
NZ_CP004081.1\|WP_002406717.1\|2777863_2780608_+\|glycoside-hydrolase-family-65-protein	gnl\|CDD\|224471	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism].	1.36625e-172
NZ_CP004081.1\|WP_002354869.1\|2785437_2785992_-\|septum-formation-protein-Maf	gnl\|CDD\|238310	cd00555, Maf, Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.	1.6551e-85
NZ_CP004081.1\|WP_002354886.1\|2770681_2771548_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	2.05803e-34
NZ_CP004081.1\|WP_002354885.1\|2771715_2773020_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	3.18356e-85
NZ_CP004081.1\|WP_002354875.1\|2780622_2781273_+\|beta-phosphoglucomutase	gnl\|CDD\|213672	TIGR01990, bPGM, beta-phosphoglucomutase. This model represents the beta-phosphoglucomutase enzyme which catalyzes the interconverison of beta-D-glucose-1-phosphate and beta-D-glucose-6-phosphate. The 6-phosphate is capable of non-enzymatic anomerization (alpha <-> beta) while the 1-phosphate is not. A separate enzyme is responsible for the isomerization of the alpha anomers. Beta-D-glucose-1-phosphate results from the phosphorylysis of maltose (2.4.1.8), trehalose (2.4.1.64) or trehalose-6-phosphate (2.4.1.216). Alternatively, these reactions can be run in the synthetic direction to create the disaccharides. All sequenced genomes which contain a member of this family also appear to contain at least one putative maltose or trehalose phosphorylase. Three species, Lactococcus, Enterococcus and Neisseria appear to contain a pair of paralogous beta-PGM's. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. These enzymes are characterized by a series of three catalytic motifs positioned within an alpha-beta (Rossman) fold. beta-PGM contains an inserted alpha helical domain in between the first and second conserved motifs and thus is a member of subfamily IA of the superfamily. The third catalytic motif comes in three variants, the third of which, containing a conserved DD or ED, is the only one found here as well as in several other related enzymes (TIGR01509). The enzyme from L. lactis has been extensively characterized including a remarkable crystal structure which traps the pentacoordinate transition state. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	7.1375e-106
NZ_CP004081.1\|WP_002354884.1\|2773012_2774281_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.15225e-51
NZ_CP004081.1\|WP_002354880.1\|2774979_2775684_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	8.69071e-14
NZ_CP004081.1\|WP_002354868.1\|2786016_2788149_-\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|223400	COG0323, MutL, DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair].	0

>NZ_CP004081.1|WP_002354875.1|2780622_2781273_+|beta-phosphoglucomutase
MTIGFIFDLDGVITDTAKFHYQAWKALADSLGISIDETFNETLKGISRMDSLDRILAHGHRENAFTPAEKEALAQQKNDHYVQLLEHLTTEDVLPGVVPLLQQAQARHIPCAVASASKNAPLILEKLGVRAYFATIVDPDSLSKGKPDPEIFLAAADSIGVLPQNAIGFEDAQSGIDGLKAAGIYAVGLSASQPLIGADMQVSEMTELSVDALLNR
>NZ_CP004081.1|WP_002406717.1|2777863_2780608_+|glycoside-hydrolase-family-65-protein
MSIQVHKEAPNMTILELTFATNQLTTTFFNHKLEPLHQKTFPFEALTIEETVPELCQLIVAEAAPILGGIVADFPEDFFSPEETLALVPQAVIQAFAEQLNTPLLTAAEQAAAPNLLAAFEEKRQYLAWHLDYYGYVPGKNEYAVESLLTVGNGFLGLRGTTPEMTISDDHYPATYIAGLYNTAASEVAGQVVENEDFVNAPDNQHIALKIGDATDWLTISPDTLQQLHRQLNLKTGLFVAEMILKDADNQQIKLTTKKIANMAQPNDYHLQYTFEPLNFSAPITLKTVTDGSVYNYNVARYRNLTAKHFQVTALSAQENKTVIEVCTNQSNLSVRETALITGDFFEKEAIMIQEEAEKIAQVVTVMAHQGTRYTLEKQVFVQASHAEQSWQVPFTPRDSFAAAAQESARAWQTLWQQANITVTGDLMSQKLLRIHSYHLLASASPFSNQAQALDVSITARGLHGEAYRGHIFWDEIFILPFYIQHYPDTAKQLLLYRYHRLEKAKENAAASQYRGAMYPWQSGRDGRETTQKLHLNPLNGHWGEDHSILQRHVSLAIAYNAWLYWHSTQDHEFMKQYGGEMLLEIAQFWNSAATLDDATGRFFIDKVMGPDEFHEGYPDQAESGLKNNAYTNLMVVWLFEELTNILALFSEEEQAQLFAKTQTSSADLARMQQIQNSLEIEVNSDGIIAQYEGYFGLKEIDWAAMKEKYGNIYRMDRILKAEGESPDDYKVAKQADTLMLFYNLDKTRVDQILEDLGYQLPADYLEKNLLYYLKRTSHGSTLSRIVHAQLAEMAQFHELSWQLYQEALYSDYRDIQGGTTAEGIHTGVMAATIHVTLATYAGVDTRQNELSICPNLPEHWQALAFQFIHQGVTYQFSLTQTSVTITADKDTQLLVQGALIPLTAERPKEVHYQ
>NZ_CP004081.1|WP_002354877.1|2776888_2777602_-|trehalose-operon-repressor
MNKFHDIFLELEQQIVQGDYQPGDLLPSENQLVETYNVSRETIRKALNLLINAGYIQKKQGKGSIVLNFKKFNFPISGVTSYKELQQTQHIESHTHVVSLEEIPVERNLAQLTGWTEGAPVWRLVRQREIEGEVDILDIDYLIKEIVPELPKHRAEDSIFDYLENDLGLAISYAQKEITVEPLTEMDKQLIGEVEGNHVVVVRSIMNLEDTRCFGYTESRHRLNKFKFVEFARRRKL
>NZ_CP004081.1|WP_002354879.1|2775779_2776493_-|WxL-domain-containing-protein
MKKKIMASLLVGSAVVGASLAPLSAQAVTTGNTPVQAEFEGGSLPDIGGDPNTVRPDPGATNSNFDLLFIPREYDFGKLSISDDLTKSIPNKNDVGTNGHVEAVGVGDLRGTKEGWHVTAQSNGMKFDEESLEGNITTSSNSLYPLEYDVVNNYFRILDFTFLDPNTSPNLVNSDNWTLDLGGDAVLVSNASVGKGQGLWQFTMFRTSLNITTPAYEIKAGAYTGNITWNLVAGPSI
>NZ_CP004081.1|WP_002354880.1|2774979_2775684_-|WxL-domain-containing-protein
MKKKIMASLLVGSAVVGASLAPLSAQAVTTGNTPVQVEFGGGVLPDHEDNTGGSVDPDPTKPNTDFDLLAIPRSFDFPLVKIGEDLTSIKSISPQFRPPSVMVGDVRGTKEGWHVTGEIAEMKNGTDKLDGQFNFGMTPYYAVFNASTGLYGGMASQNGMNITDDPTAPSFIGTNMTIGGGATTLMNATVGQGQGTWSGRIDNMTLNVTTPYQQIKAGAYTGNITWNLVAGPSI
>NZ_CP004081.1|WP_002354883.1|2774489_2774939_+|large-conductance-mechanosensitive-channel-protein-MscL
MIKEFKEFIMRGSVLDLAVGVVIGSAFTAIVTQVVEGLITPLISLIFVLTTGKKSADDALGALVYKVEGVEFNIGSVISALITFLITAFVLFLIVKAANKMKNRGKKEEAAEEEVVPTSEDYLKEIRDLLAAQTPPAETVKTDSTFTEK
>NZ_CP004081.1|WP_002354884.1|2773012_2774281_-|insulinase-family-protein
MSVQLVKGVNLHVIPTEKYKTVRLLVRFNTRLNHETITKRTLLSSLMETNSLNYPNQVKLSERLAELYGASFGIGVSKKGNQHWFNISMNIVNDHYLQDSQVLAEAVDFLKEIIFAPNIQAGQFEAETFQREKENLKAYLESIVEDKQTYASLALQSVYFNQSEDQKIPSFGTVAALAEETAASLAAYYQKMLAEDQVDIFVLGDVNEAELVPLFKQLPFTPREEGKAAIFYNQPIRNVIEERTEREVLAQSKLNLAYNTDIYYGDSYYFALQVFNGIFGGFPHSKLFMNVREKEHLAYYASSSIDTFRGFMTVQTGIDGKNRNQVLRLISTELENIRLGKISELEIEQTKAMLKNQYILALDNAGAWLEKEYLNELMPQTMLTAEEWIARINAVTISEIQEVAKRLELQAIFFLEGETEND
>NZ_CP004081.1|WP_002354885.1|2771715_2773020_-|insulinase-family-protein
MIKKDYAQIKETLYTETLANGLKVYLLPKNDFQKTYGLFTTDYGSIDNTFVPIGQEEMIEVPDGIAHFLEHKMFEKEDGDVFQKFGQQGASANAFTSFTKTSYLFSTTDQVTQNLETLLDFVQSPYFTKETVEKEKGIIGQEIQMYLDDPNWRLFFGILGNLYPKHPLHIDIAGTVASIAEITAEDLYTCYNTFYHPSNMTLFVVGKMDPEALMAFIRENQAAKEFPAAQPIRRHFPEETAADIVKESAIEMAVTRAKVLVGLKGLDEVPTTGRDLMKYQVTVNLLLQLLFGNTSQNYLALYDEGLLDDSFSYDFNLDRSFHFADIGGDSEQPEVLAERIEAILLSATTSPELTEENLSLLKKKMIGKYFQSLNSLEYIANQFSQSLFGETTLFDKIEVIESIQLADVRQVAETLIREEGLSRFYMYPKGETEQ
>NZ_CP004081.1|WP_002354886.1|2770681_2771548_-|helix-turn-helix-domain-containing-protein
MASVNIGETLKEARLQKNISIDELQQMTKIQKRYLEIIEQNDFESLPGTFYVRAFIRQYASAVGLDGNQLVDIYDGKEPAIVEEPKPVYEELEGSRKQLHDEEKQSSWLLRNLPAIAFSLIGLAIAVVVLYIMWQDQKAEPIIQTPATSTSVEKPKESSQAPESSTQSSTPPSSSSEPEKKTAVAVVSDANNQVTATVKDANSPINITFKGTEGSCWIGVMVDGNYTYQHTLQAGETETTALPANAANATLILGASNNVAIQVDGADLTLEKTPVLIRKDVTLGITYR
>NZ_CP004081.1|WP_002354887.1|2770122_2770377_-|hypothetical-protein
MVKIASNQGAAQKAIAGIKSVSVNKNQICHLGESNISSMKKGVKVSNQLLNQLAKVVNGVNAQANKFPKLAATIAARDSQTTFK
>NZ_CP004081.1|WP_002392696.1|2782522_2782666_-|putative-holin-like-toxin
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK
>NZ_CP004081.1|WP_002381060.1|2783721_2784693_-|ribose-phosphate-diphosphokinase
MSKHYFDPRLKIFSLNSNRPLAEKIADAVGVELGKCSVTQFSDGEIQVNIEESIRGAHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYARQDRKARAREPITAKLVANMIEKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIADYFIEHGIQGDDVVVVSPDHGGVTRARKLAEFLKAPIAIIDKRRPKANVAEVMNIIGHVEGKTCVLIDDMIDTAGTISLAANALKEAGAKDVYASCTHPVLSGPALQRIEDSAIERLVVTDSIYLSDDRKIAKIDEVSVGELIGDAIKRIHENKPVSPLFETKNK
>NZ_CP004081.1|WP_002354871.1|2784867_2785305_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MTKPTEEELKQTLTDLQYAVTQENATERPFSGEYDDFYQDGIYVDIVSGEPLFSSLDKYDAGCGWPSFTKPIEKRGVKEKADFSHGMHRVEVRSQEADSHLGHVFTDGPLQEGGLRYCINAAALRFVPVADLEKEGYGEYLSLFK
>NZ_CP004081.1|WP_002354869.1|2785437_2785992_-|septum-formation-protein-Maf
MQIILASQSPRRQELLKRVVPTFTIAPADIDETVGKDGLPAEYVAQMAAQKAAAIAEQSPEALVIGCDTIVALAGEILGKPTSREDGYRMLRLLSGKTHDVYTSVTLKQGEKERSATVHSTVTFYPLTDTEIHAYLDTAEYADKAGAYGIQGQGALLIEAIAGDYYAIMGLPIAKVARLLKEFN
>NZ_CP004081.1|WP_002354868.1|2786016_2788149_-|DNA-mismatch-repair-endonuclease-MutL
MGKIQELSEQLANQIAAGEVVERPASVVKELVENALDAGSTQIDIFIEEAGLKTIQIIDNGEGIAKEDVLNAFKRHATSKIHTRDDLFRIRSLGFRGEALPSIASVSEMIVETATAEEEEGSYVILKGGKVEENRPAALRKGTKMTVSNLFYNTPARLKYVKTIQTELANIGDIVNRLALSHPKVAFRLVHDGHKMMSTTGNGDLKQTIAGIYGISTAKKMLKIEGKDLDFTLTGYVSLPEVTRASRNYLSTIINGRYIKNFALNKAIVAGYGSKLMVGRFPIAVLEIEMDPLLVDVNVHPTKQEVRLSKEKDLMALIEQAIQEVLSQEQLIPNAADNLRFKKKLPPEPKAEQMEIPLSTEQPAVKQRPGSLSYNPATGRFYAEHATDETPASSAPEAVNQTERAVDPMDDPFAPPVPESTSVAEETSAYETSSAAVDSENHWETASNEQQVIAEETKITEVPDSEPSLRSSEAADEVFQEEMKLHPEFDANSATSQRELKQALNKLEEERPTERFPELEYFGQMHGTYLFAQSKDGLFIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPIVIDYPNSDALKIKEQKETLAEVGIHLEDFGQNSFIVRAHPTWYPAGEEESIVREMIDMLLTTGSVSVKKFREATAIMMSCKRSIKANHYLNEQQARVLLKDLALCENPFNCPHGRPVLIHFTNSDMERMFKRIQDPH
>NZ_CP004081.1|WP_002354867.1|2788180_2790757_-|DNA-mismatch-repair-protein-MutS
MPQKTKNTPMMEQYLSIKAQYKDAFLFYRLGDFYELFYEDAINAAQILELTLTSRNRNADDPIPMCGVPYHAAQGYIDTLIEQGYKVAICEQVEDPKTTKGMVKREVVQLVTPGTVMNSKGLEAKDNNYLTAVLTDGNQFGFAYVDLSTGELKTAVLADEEGVLNEASALQTKEMVLGSGIPESLKENLSLRLNIIFSTQETVEENAEFSFLTNELINPLEIEITGKLLSYLSVTQKRSLSHIQKAVEYQPDHFLKMDHYSKFNLELSQSIRTGQKKGTLLWLLDETKTAMGGRLLKQWLDRPLIQERQIKARQEMVQSLLNAYFERLDLQAALTNVYDLERLAGRVAFGSVNGRDLIQLRTSLEQVPTIRQLIVGINQGEWDDLLVDLNPVEDLVALIATAINEEAPLQITEGNVIKDGYNDQLDEYRDAMRNGKQWLAELEAKERQETGIKNLKIGYNRVFGYFIEITKSNLANLEEGKYERKQTLANAERFITPELKELERLILEAEEKSVELEYQLFLAVREQVKTNIDRLQTLAKTISAVDVLQSFATISERYQYVRPTLRSNTKNLAIVEGRHPVVEKVLGHQEYIPNSIRMNPETDILLITGPNMSGKSTYMRQLALTVVMAQIGCFVPAESAEMPIFDQIFTRIGASDDLIAGQSTFMVEMMEANQALRHATPNSLILFDELGRGTATYDGMALAQAIIEYIHREVQAKTLFSTHYHELTVLDETLKGLKNIHVGAVEKDGEVVFLHKMMEGPADKSYGIHVAKIAGLPSPLLERAATILSALEAEETTIPSSVHHEEVSEVHEETEQLSLFKEVSTEELSVIDTLKKMNLLEMTPLDALNMLHQLQKRI
>NZ_CP004081.1|WP_002354866.1|2790757_2791129_-|YlbF-family-regulator
MEPLNLDAQSNKELEKLLHLIGQDEVIQRYQAIEEKVKKNKKLTELVEEIKAAQKDAVQFAHYGKPTAEKEAIQRADAKTKEFDEHPLVVAYREQLIEANDLVQHVTALIQYRVNEELEKEGN
>NZ_CP004081.1|WP_002375504.1|2791216_2792014_-|TIGR00282-family-metallophosphoesterase
MRILFIGDVVGSLGREALATYVPKLKKKYRPQVTIANGENAASGRGITGKIYKKFLQDGVDVVTMGNHTWDNKDIFEFIDDAKKMVRPANFSEDVPGQGMVFVKVNQLELAVINLQARTFMVPLEDPFKKAAELVAIARKRTPLIFVDFHGETTSEKQAMSWFLDGQVSAVVGTHTHVQTNDARILPKGTAFLSDVGMTGPYDGILGMKREPIIEKFMTALPKRFEVVETGRTILSACILEIDDQTGQAKMIEPIQISEDRPFQE
>NZ_CP004081.1|WP_002354863.1|2792173_2793730_-|ribonuclease-Y
MVLNILLAIVGLIVGLGLGFVIAKSRHDKAINGAKISASSILENARKESETLKKEALLEAKEENQKYRSEIESELKESRLELKSQENRLIQREQTLDRKDDSLEKREGSLEEKEEKLGARQQLIDEREKEVENLINQQHQELERIASLSKEEAKSIIMKSTEEELNHELTLMVKESEQRAKEESDRKAKNLLSLAIQRCAADSVSETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPARIEEMVEKSRKEMDERIREYGEQAAFEVGAHTLHPDLIKILGRLRFRTSYGQNVLNHSIEVAKLAGVLAAELGEDVQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYKENSVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLENLENISNSFEGVDSSFAVQAGREVRVMVKPEEISDLESVRLVRDIRKKIEDDLDYPGHIKVTVIRETRAVDYAK
>NZ_CP004081.1|WP_002392698.1|2793925_2794057_-|hypothetical-protein
MFRTKLLNRLLSMSEPIHIKQLSQTADYAAFVLKFKQFVMAET

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	MF157411	Escherichia coli strain EC1000 plasmid pCR2, complete sequence	304-333	0	1.0
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NZ_CP022485	Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence	4124-4153	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	38052-38081	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	1579-1608	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	CP002493	Enterococcus faecalis 62 plasmid EF62pB, complete sequence	38720-38749	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	43030-43059	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	47853-47882	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	53323-53352	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NC_006827	Enterococcus faecalis plasmid pCF10, complete sequence	59015-59044	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	40051-40080	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NZ_CP028283	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed3, complete sequence	4491-4520	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NZ_CP042215	Enterococcus faecalis strain L15 plasmid pL15-A, complete sequence	4208-4237	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NZ_MG765452	Enterococcus faecalis strain E512 plasmid pE512, complete sequence	16118-16147	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	41009-41038	1	0.967
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	CAJDJX010000002	Enterococcus phage Q69 genome assembly, contig: phageQ69-genome, whole genome shotgun sequence	31516-31545	1	0.967
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	NZ_CP041739	Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence	24217-24246	2	0.933
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	MK721199	Enterococcus phage vB_EfaS_Ef5.1, complete genome	28065-28094	2	0.933
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	MK721190	Enterococcus phage vB_EfaS_Ef6.4, complete genome	27969-27998	2	0.933
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	MK721200	Enterococcus phage vB_EfaS_Ef5.3, complete genome	28357-28386	2	0.933
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	NC_031260	Enterococcus phage Ec-ZZ2, complete genome	981-1010	2	0.933
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	KF733017	Enterococcus phage IME-EF4, complete genome	11644-11673	2	0.933
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	CAJDKF010000002	Enterococcus phage vB_EfaS_159 genome assembly, contig: phage159-genome, whole genome shotgun sequence	32054-32083	3	0.9
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	KF728385	Enterococcus phage IME_EF3, complete genome	29904-29933	3	0.9
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	KJ127304	Enterococcus phage AUEF3, partial genome	19398-19427	3	0.9
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	MK496783	Capybara microvirus Cap3_SP_410, complete genome	3412-3441	6	0.8
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	MN693358	Marine virus AFVG_25M395, complete genome	6141-6170	6	0.8
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	MN694190	Marine virus AFVG_250M608, complete genome	30089-30118	6	0.8
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	MT074134	Bacteroides phage ARB14, complete genome	36880-36909	6	0.8
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	MT074143	Bacteroides phage HNL05, complete genome	37280-37309	6	0.8
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	MT074135	Bacteroides phage ARB25, complete genome	36793-36822	6	0.8
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	MT074144	Bacteroides phage HNL35, complete genome	37321-37350	6	0.8
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NC_014502	Gloeothece verrucosa PCC 7822 plasmid Cy782203, complete sequence	268334-268363	7	0.767
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP032754	Lactobacillus plantarum subsp. argentoratensis strain DSM 16365 plasmid unnamed3, complete sequence	26827-26856	7	0.767
NZ_CP004081_1	1.2\|1934385\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934385-1934414	30	MN694044	Marine virus AFVG_250M514, complete genome	29776-29805	7	0.767
NZ_CP004081_1	1.3\|1934451\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934451-1934480	30	LN997845	Streptomyces reticuli genome assembly TUE45, plasmid : IV	17579-17608	7	0.767
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	NZ_CP011146	Bacillus cereus strain FORC_013 plasmid pFORC13, complete sequence	156576-156605	7	0.767
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP028270	Pediococcus pentosaceus strain SRCM102740 plasmid unnamed1, complete sequence	22740-22769	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP028267	Pediococcus pentosaceus strain SRCM102739 plasmid unnamed1, complete sequence	9446-9475	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP015919	Pediococcus pentosaceus strain wikim20 plasmid pKPP01, complete sequence	11178-11207	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP021931	Lactobacillus plantarum strain TMW 1.1308 plasmid pL11308-1, complete sequence	27801-27830	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP024059	Lactobacillus plantarum strain KACC 92189 plasmid unnamed1	53320-53349	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP028265	Pediococcus pentosaceus strain SRCM102738 plasmid unnamed1, complete sequence	32031-32060	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP018326	Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-2, complete sequence	38976-39005	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP019582	Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence	10189-10218	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP035308	Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence	20537-20566	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP029972	Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence	6123-6152	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP029967	Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence	28417-28446	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	LT615366	Enterococcus phage VPE25 genome assembly, chromosome: VPE25	14742-14771	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	LT546029	Enterococcus phage VFW genome assembly, chromosome: VFW	14675-14704	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	LT546030	Enterococcus phage VPE25 genome assembly, chromosome: I	14742-14771	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	MT119360	Enterococcus phage nattely, complete genome	14821-14850	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP037431	Lactobacillus plantarum strain EM plasmid pEM2, complete sequence	20908-20937	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP025692	Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence	133-162	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP035559	Lactobacillus plantarum strain SRCM103297 plasmid unnamed3	24727-24756	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP035572	Lactobacillus plantarum strain SRCM103303 plasmid unnamed1	22589-22618	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP035175	Lactobacillus plantarum strain SRCM103426 plasmid unnamed1	87952-87981	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP018327	Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-3, complete sequence	992-1021	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP035116	Lactobacillus plantarum strain SRCM103295 plasmid unnamed3	94597-94626	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP018798	Lactobacillus parabuchneri strain FAM21731 plasmid pFAM21731.2, complete sequence	27103-27132	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP025415	Lactobacillus plantarum strain X7021 plasmid unnamed3, complete sequence	13215-13244	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP021928	Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-2, complete sequence	6938-6967	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP035145	Lactobacillus plantarum strain SRCM103357 plasmid unnamed2	36987-37016	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP050806	Lactobacillus plantarum strain SPC-SNU 72-2 plasmid pLBP752, complete sequence	19494-19523	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP028277	Lactobacillus plantarum strain SRCM100995 plasmid unnamed2, complete sequence	54324-54353	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP013152	Lactobacillus plantarum strain MF1298 plasmid pMF1298-4, complete sequence	22761-22790	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	MT119361	Enterococus phage vipetofem, complete genome	70537-70566	8	0.733
NZ_CP004081_1	1.3\|1934451\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934451-1934480	30	NZ_CP014003	Synechococcus sp. PCC 73109 plasmid unnamed5, complete sequence	12742-12771	8	0.733
NZ_CP004081_1	1.5\|1934583\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934583-1934612	30	MH598801	Pelagibacter phage HTVC200P, complete genome	5285-5314	8	0.733
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	NZ_CP047122	Lactobacillus hilgardii strain FLUB plasmid unnamed1	39415-39444	9	0.7
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	KM359505	Prochlorococcus phage P-TIM68, complete genome	108590-108619	9	0.7
NZ_CP004081_1	1.1\|1934319\|30\|NZ_CP004081\|CRISPRCasFinder	1934319-1934348	30	KY971610	Pseudomonas phage PspYZU05, complete genome	121642-121671	9	0.7
NZ_CP004081_1	1.4\|1934517\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934517-1934546	30	NZ_CP045274	Bacillus megaterium strain FDU301 plasmid pFDU301B, complete sequence	28090-28119	9	0.7
NZ_CP004081_1	1.5\|1934583\|30\|NZ_CP004081\|CRISPRCasFinder,PILER-CR,CRT	1934583-1934612	30	MN693806	Marine virus AFVG_250M575, complete genome	23977-24006	9	0.7

1. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to MF157411 (Escherichia coli strain EC1000 plasmid pCR2, complete sequence) position: , mismatch: 0, identity: 1.0

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aggggagaaaaagccaaatcaaaaaagttt	Protospacer
******************************

2. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP022485 (Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

3. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgtaaatcacaatcttttgtaagtc	Protospacer
****************.*************

4. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

5. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to CP002493 (Enterococcus faecalis 62 plasmid EF62pB, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

6. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

7. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

8. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

9. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NC_006827 (Enterococcus faecalis plasmid pCF10, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgtaaatcacaatcttttgtaagtc	Protospacer
****************.*************

10. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

11. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP028283 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

12. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP042215 (Enterococcus faecalis strain L15 plasmid pL15-A, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

13. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_MG765452 (Enterococcus faecalis strain E512 plasmid pE512, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

14. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

15. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to CAJDJX010000002 (Enterococcus phage Q69 genome assembly, contig: phageQ69-genome, whole genome shotgun sequence) position: , mismatch: 1, identity: 0.967

tatggttttgaataaattgtacatcattat	CRISPR spacer
tatggttttgaataaattgcacatcattat	Protospacer
*******************.**********

16. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP041739 (Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence) position: , mismatch: 2, identity: 0.933

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacaatcttttgtaagtc	Protospacer
*******.********.*************

17. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to MK721199 (Enterococcus phage vB_EfaS_Ef5.1, complete genome) position: , mismatch: 2, identity: 0.933

tatggttttgaataaattgtacatcattat	CRISPR spacer
tatggttttgaatgaattgcacatcattat	Protospacer
*************.*****.**********

18. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to MK721190 (Enterococcus phage vB_EfaS_Ef6.4, complete genome) position: , mismatch: 2, identity: 0.933

tatggttttgaataaattgtacatcattat	CRISPR spacer
tgtggttttgaatgaattgtacatcattat	Protospacer
*.***********.****************

19. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to MK721200 (Enterococcus phage vB_EfaS_Ef5.3, complete genome) position: , mismatch: 2, identity: 0.933

tatggttttgaataaattgtacatcattat	CRISPR spacer
tatggttttgaatgaattgcacatcattat	Protospacer
*************.*****.**********

20. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NC_031260 (Enterococcus phage Ec-ZZ2, complete genome) position: , mismatch: 2, identity: 0.933

tatggttttgaataaattgtacatcattat	CRISPR spacer
tatggttttgaatgaattgcacatcattat	Protospacer
*************.*****.**********

21. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to KF733017 (Enterococcus phage IME-EF4, complete genome) position: , mismatch: 2, identity: 0.933

tatggttttgaataaattgtacatcattat	CRISPR spacer
tatggttttgaatgaattgcacatcattat	Protospacer
*************.*****.**********

22. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to CAJDKF010000002 (Enterococcus phage vB_EfaS_159 genome assembly, contig: phage159-genome, whole genome shotgun sequence) position: , mismatch: 3, identity: 0.9

tatggttttgaataaattgtacatcattat	CRISPR spacer
tgtggttttgaatgaattgcacatcattat	Protospacer
*.***********.*****.**********

23. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to KF728385 (Enterococcus phage IME_EF3, complete genome) position: , mismatch: 3, identity: 0.9

tatggttttgaataaattgtacatcattat	CRISPR spacer
tgtggttttgaatgaattgaacatcattat	Protospacer
*.***********.***** **********

24. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to KJ127304 (Enterococcus phage AUEF3, partial genome) position: , mismatch: 3, identity: 0.9

tatggttttgaataaattgtacatcattat	CRISPR spacer
tgtggttttgaatgaattgcacatcattat	Protospacer
*.***********.*****.**********

25. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to MK496783 (Capybara microvirus Cap3_SP_410, complete genome) position: , mismatch: 6, identity: 0.8

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
agggcagaaaaagccaaatcaagaattatc	Protospacer
**** *****************.**   *.

26. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to MN693358 (Marine virus AFVG_25M395, complete genome) position: , mismatch: 6, identity: 0.8

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aacgcacaaaaagcccaatcaaaaaagatt	Protospacer
*. * * ******** *********** **

27. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to MN694190 (Marine virus AFVG_250M608, complete genome) position: , mismatch: 6, identity: 0.8

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
tggagtgcgaaagccaaatcaaaaaaggtt	Protospacer
 **.* * .****************** **

28. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to MT074134 (Bacteroides phage ARB14, complete genome) position: , mismatch: 6, identity: 0.8

tatggttttgaataaattgtacatcattat	CRISPR spacer
aaaggttttgaataaattgtatatcgaaat	Protospacer
 * ******************.***.  **

29. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to MT074143 (Bacteroides phage HNL05, complete genome) position: , mismatch: 6, identity: 0.8

tatggttttgaataaattgtacatcattat	CRISPR spacer
aaaggttttgaataaattgtatatcgaaat	Protospacer
 * ******************.***.  **

30. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to MT074135 (Bacteroides phage ARB25, complete genome) position: , mismatch: 6, identity: 0.8

tatggttttgaataaattgtacatcattat	CRISPR spacer
aaaggttttgaataaattgtatatcgaaat	Protospacer
 * ******************.***.  **

31. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to MT074144 (Bacteroides phage HNL35, complete genome) position: , mismatch: 6, identity: 0.8

tatggttttgaataaattgtacatcattat	CRISPR spacer
aaaggttttgaataaattgtatatcgaaat	Protospacer
 * ******************.***.  **

32. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NC_014502 (Gloeothece verrucosa PCC 7822 plasmid Cy782203, complete sequence) position: , mismatch: 7, identity: 0.767

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aatcaacaaaaagccaaaacaaaaaagtta	Protospacer
*.  .* *********** **********

33. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP032754 (Lactobacillus plantarum subsp. argentoratensis strain DSM 16365 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaatttct	Protospacer
*.  ********* ***********  *.*

34. spacer 1.2|1934385|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to MN694044 (Marine virus AFVG_250M514, complete genome) position: , mismatch: 7, identity: 0.767

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
aactgcataaatcacaggcttttgtaagcc	Protospacer
 *. .*.********** **********.*

35. spacer 1.3|1934451|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to LN997845 (Streptomyces reticuli genome assembly TUE45, plasmid : IV) position: , mismatch: 7, identity: 0.767

tggtc--gcagtttccgctcgaactgcttttc	CRISPR spacer
--gtcgagcagtttccgctcgaactcctccga	Protospacer
  ***  ****************** **..

36. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP011146 (Bacillus cereus strain FORC_013 plasmid pFORC13, complete sequence) position: , mismatch: 7, identity: 0.767

tatggttttgaataaattgtacatcattat	CRISPR spacer
aagttttttgaataaaatgtacctcattag	Protospacer
 *   *********** ***** ******

37. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP028270 (Pediococcus pentosaceus strain SRCM102740 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

38. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP028267 (Pediococcus pentosaceus strain SRCM102739 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

39. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP015919 (Pediococcus pentosaceus strain wikim20 plasmid pKPP01, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

40. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP021931 (Lactobacillus plantarum strain TMW 1.1308 plasmid pL11308-1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

41. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP024059 (Lactobacillus plantarum strain KACC 92189 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

42. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP028265 (Pediococcus pentosaceus strain SRCM102738 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

43. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP018326 (Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

44. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP019582 (Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

45. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP035308 (Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

46. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP029972 (Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

47. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP029967 (Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

48. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to LT615366 (Enterococcus phage VPE25 genome assembly, chromosome: VPE25) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

49. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to LT546029 (Enterococcus phage VFW genome assembly, chromosome: VFW) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

50. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to LT546030 (Enterococcus phage VPE25 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

51. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to MT119360 (Enterococcus phage nattely, complete genome) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

52. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP037431 (Lactobacillus plantarum strain EM plasmid pEM2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

53. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP025692 (Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

54. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP035559 (Lactobacillus plantarum strain SRCM103297 plasmid unnamed3) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

55. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP035572 (Lactobacillus plantarum strain SRCM103303 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

56. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP035175 (Lactobacillus plantarum strain SRCM103426 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

57. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP018327 (Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-3, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

58. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP035116 (Lactobacillus plantarum strain SRCM103295 plasmid unnamed3) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

59. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP018798 (Lactobacillus parabuchneri strain FAM21731 plasmid pFAM21731.2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

60. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP025415 (Lactobacillus plantarum strain X7021 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

61. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP021928 (Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

62. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP035145 (Lactobacillus plantarum strain SRCM103357 plasmid unnamed2) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

63. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP050806 (Lactobacillus plantarum strain SPC-SNU 72-2 plasmid pLBP752, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

64. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP028277 (Lactobacillus plantarum strain SRCM100995 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

65. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP013152 (Lactobacillus plantarum strain MF1298 plasmid pMF1298-4, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

66. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to MT119361 (Enterococus phage vipetofem, complete genome) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

67. spacer 1.3|1934451|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP014003 (Synechococcus sp. PCC 73109 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.733

tggtcgcagtttccgctcgaactgcttttc	CRISPR spacer
gtgctgcaatttccggtcgaactgctttat	Protospacer
  *..***.****** ************ .

68. spacer 1.5|1934583|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to MH598801 (Pelagibacter phage HTVC200P, complete genome) position: , mismatch: 8, identity: 0.733

gtctttaaagtaaccagtaacataataacc	CRISPR spacer
tggattaaaataaccagttacataataaaa	Protospacer
    *****.******** *********

69. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to NZ_CP047122 (Lactobacillus hilgardii strain FLUB plasmid unnamed1) position: , mismatch: 9, identity: 0.7

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
taacatctcaaagccaaatcaaaaaagttt	Protospacer
 .. .    *********************

70. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 9, identity: 0.7

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
caaagagaaaaagcaaaattaaaaaaggaa	Protospacer
 ...********** ****.*******

71. spacer 1.1|1934319|30|NZ_CP004081|CRISPRCasFinder matches to KY971610 (Pseudomonas phage PspYZU05, complete genome) position: , mismatch: 9, identity: 0.7

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
gaaagagaaaaagcaaaatcaaaaacctaa	Protospacer
....********** **********  *

72. spacer 1.4|1934517|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to NZ_CP045274 (Bacillus megaterium strain FDU301 plasmid pFDU301B, complete sequence) position: , mismatch: 9, identity: 0.7

tatggttttgaataaattgtacatcattat	CRISPR spacer
ataggtttttaataaattgtaaatcaagtg	Protospacer
   ****** *********** ****

73. spacer 1.5|1934583|30|NZ_CP004081|CRISPRCasFinder,PILER-CR,CRT matches to MN693806 (Marine virus AFVG_250M575, complete genome) position: , mismatch: 9, identity: 0.7

gtctttaaagtaaccagtaacataataacc	CRISPR spacer
agctttagagtaaccattaacataaccttt	Protospacer
. *****.******** ********.  ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

264742 : 302101

Enterococcus_phage(100.0%)

capsid,portal,integrase,head,holin,tail

attL 264633:264649|attR 302392:302408

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
264633:264649	attL	NA	NA	NA	NA
WP_002379954.1\|264742_265957_-\|integrase	site-specific integrase	D2J023	Enterococcus_phage	1.2e-223	100.0
WP_010706904.1\|266112_266643_-	hypothetical protein	D2J024	Enterococcus_phage	1.7e-86	100.0
WP_010706903.1\|266678_267356_-	ImmA/IrrE family metallo-endopeptidase	D2J025	Enterococcus_phage	4.2e-125	100.0
WP_002379958.1\|267375_267738_-	helix-turn-helix transcriptional regulator	D2J026	Enterococcus_phage	5.8e-57	100.0
WP_002379959.1\|267845_268076_+	helix-turn-helix transcriptional regulator	D2J027	Enterococcus_phage	3.1e-32	100.0
WP_002379960.1\|268155_268509_+	DUF1140 family protein	D2J028	Enterococcus_phage	4.9e-61	99.1
WP_002379961.1\|268514_268787_+	excisionase	D2J029	Enterococcus_phage	1.7e-45	100.0
WP_002379962.1\|268790_268985_+	hypothetical protein	D2J030	Enterococcus_phage	1.1e-27	100.0
WP_002379963.1\|268999_269200_+	hypothetical protein	D2J031	Enterococcus_phage	7.9e-32	100.0
WP_002379964.1\|269196_269379_+	hypothetical protein	D2J032	Enterococcus_phage	7.2e-24	100.0
WP_002379965.1\|269379_269574_+	hypothetical protein	D2J033	Enterococcus_phage	6.7e-28	100.0
WP_002392906.1\|270410_270593_+	hypothetical protein	D2J035	Enterococcus_phage	9.1e-27	100.0
WP_002379969.1\|270579_271059_+	hypothetical protein	D2J036	Enterococcus_phage	8.2e-59	100.0
WP_002379970.1\|271061_272234_+	DUF2800 domain-containing protein	D2J037	Enterococcus_phage	4.0e-224	100.0
WP_002379971.1\|272239_272482_+	hypothetical protein	D2J038	Enterococcus_phage	4.9e-36	100.0
WP_010706762.1\|272497_272827_+	hypothetical protein	D2J039	Enterococcus_phage	1.4e-54	100.0
WP_002379973.1\|272853_273429_+	DUF2815 family protein	D2J040	Enterococcus_phage	5.5e-102	99.5
WP_002416140.1\|273463_273706_+	hypothetical protein	D2J041	Enterococcus_phage	2.7e-34	100.0
WP_002418131.1\|273692_274241_+	hypothetical protein	D2J042	Enterococcus_phage	4.7e-95	100.0
WP_010711931.1\|274237_276199_+	DNA polymerase	D2J043	Enterococcus_phage	0.0e+00	99.4
WP_024797208.1\|276245_276440_+	hypothetical protein	NA	NA	NA	NA
WP_010711933.1\|276451_276649_+	hypothetical protein	A0A0C5K8R7	Enterococcus_phage	9.5e-14	61.5
WP_010711935.1\|276950_279383_+	hypothetical protein	D2J048	Enterococcus_phage	0.0e+00	99.1
WP_010706758.1\|279715_280036_+	VRR-NUC domain-containing protein	D2J049	Enterococcus_phage	1.6e-55	100.0
WP_002392903.1\|280036_281416_+	DEAD/DEAH box helicase	D2J050	Enterococcus_phage	9.0e-268	100.0
WP_002392902.1\|281559_282030_+	hypothetical protein	D2J051	Enterococcus_phage	9.1e-79	100.0
WP_010711936.1\|282116_282683_+	hypothetical protein	D2J052	Enterococcus_phage	3.2e-102	100.0
WP_010711937.1\|282679_283936_+	hypothetical protein	D2J053	Enterococcus_phage	7.7e-242	100.0
WP_010826309.1\|284083_284302_-	hypothetical protein	D2J055	Enterococcus_phage	5.9e-33	100.0
WP_010711940.1\|284383_285916_+\|portal	phage portal protein	D2J056	Enterococcus_phage	1.4e-290	99.8
WP_014862098.1\|285845_287546_+\|head	head protein	D2J057	Enterococcus_phage	0.0e+00	100.0
WP_002417770.1\|287542_287878_+	hypothetical protein	D2J058	Enterococcus_phage	4.5e-56	100.0
WP_010711943.1\|287924_288224_+	hypothetical protein	D2J059	Enterococcus_phage	4.8e-49	100.0
WP_010711944.1\|288360_288933_+	phage scaffolding protein	D2J060	Enterococcus_phage	1.9e-94	100.0
WP_010711945.1\|288948_289812_+\|capsid	phage capsid protein	D2J061	Enterococcus_phage	2.4e-157	100.0
WP_160747725.1\|289846_289984_-	hypothetical protein	NA	NA	NA	NA
WP_010711946.1\|290114_290648_+	hypothetical protein	D2J063	Enterococcus_phage	1.1e-93	99.4
WP_002392896.1\|290647_290986_+\|head,tail	head-tail adaptor protein	D2J064	Enterococcus_phage	1.0e-60	100.0
WP_002403769.1\|290972_291404_+	HK97 gp10 family phage protein	D2J065	Enterococcus_phage	7.8e-77	100.0
WP_002380000.1\|291407_291791_+	hypothetical protein	D2J066	Enterococcus_phage	2.2e-67	100.0
WP_002417767.1\|291777_292737_+	fibronectin type III domain-containing protein	D2J067	Enterococcus_phage	1.3e-177	99.7
WP_002380002.1\|292795_293236_+	hypothetical protein	D2J068	Enterococcus_phage	1.9e-70	100.0
WP_002417411.1\|293325_293550_+	hypothetical protein	D2J069	Enterococcus_phage	4.4e-31	97.3
WP_024797207.1\|293549_296783_+\|tail	tail protein	D2J070	Enterococcus_phage	0.0e+00	99.0
WP_002417416.1\|296795_297671_+\|tail	phage tail family protein	D2J071	Enterococcus_phage	1.3e-166	100.0
WP_002417415.1\|297670_298756_+	siphovirus ReqiPepy6 Gp37-like family protein	D2J072	Enterococcus_phage	2.1e-203	100.0
WP_010711948.1\|298766_299774_+	hypothetical protein	D2J073	Enterococcus_phage	8.2e-178	100.0
WP_024797206.1\|299774_300311_+	hypothetical protein	D2J074	Enterococcus_phage	2.4e-91	96.1
WP_002379918.1\|300333_300588_+	hemolysin XhlA family protein	D2J075	Enterococcus_phage	8.5e-39	100.0
WP_010711950.1\|300590_300797_+\|holin	phage holin	A0A0S2MYF6	Enterococcus_phage	7.6e-30	98.5
WP_010711951.1\|300799_302101_+	LysM peptidoglycan-binding domain-containing protein	D2J077	Enterococcus_phage	2.0e-240	100.0
302392:302408	attR	NA	NA	NA	NA

DBSCAN-SWA_2

427612 : 496803

Streptococcus_phage(35.0%)

transposase,integrase,protease

attL 417491:417507|attR 485543:485559

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
417491:417507	attL	NA	NA	NA	NA
WP_002355370.1\|427612_428212_+\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	2.5e-28	35.6
417491:417507	attL	NA	NA	NA	NA
WP_002386101.1\|429995_431183_+	nucleotide sugar dehydrogenase	M1HV26	Paramecium_bursaria_Chlorella_virus	4.2e-96	48.6
WP_002355375.1\|431219_432413_+	glycosyltransferase	M1H5V3	Paramecium_bursaria_Chlorella_virus	1.1e-43	32.4
WP_002370946.1\|432570_433530_+\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
WP_002363024.1\|433703_434300_+	HTH domain-containing protein	NA	NA	NA	NA
WP_108120410.1\|434594_435967_-\|transposase	IS3-like element ISLla3 family transposase	A0A1B1P773	Bacillus_phage	9.2e-55	43.4
WP_002355383.1\|436349_437699_-	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	5.8e-118	51.4
WP_002355386.1\|437836_438460_-	cysteine hydrolase	NA	NA	NA	NA
WP_002384811.1\|438486_438651_-	hypothetical protein	NA	NA	NA	NA
WP_002355388.1\|438724_439315_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_042341262.1\|439654_439915_+	DUF3102 domain-containing protein	J7KDG2	Streptococcus_phage	1.4e-12	49.4
WP_002355390.1\|440064_440589_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	4.3e-21	38.6
WP_002389371.1\|440589_440943_+\|transposase	transposase	NA	NA	NA	NA
WP_002355391.1\|441058_441400_-	hypothetical protein	NA	NA	NA	NA
WP_002355392.1\|441518_442460_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_025257710.1\|442504_443764_-\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_002386104.1\|444065_444218_-	hypothetical protein	NA	NA	NA	NA
WP_002355395.1\|444318_444555_+	helix-turn-helix transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	1.6e-12	50.7
WP_002355397.1\|444973_447088_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	5.9e-117	38.7
WP_002355404.1\|449671_450400_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002355406.1\|450576_451503_+	hypothetical protein	NA	NA	NA	NA
WP_002363033.1\|451519_452803_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
451697:451713	attR	NA	NA	NA	NA
WP_002363034.1\|453190_454087_+	ParA family protein	A0A1X9I765	Streptococcus_phage	6.3e-153	98.6
451697:451713	attR	NA	NA	NA	NA
WP_002363035.1\|454163_454373_+	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	1.3e-29	95.7
WP_002326825.1\|454389_454662_+	antitoxin	A0A1X9I6E5	Streptococcus_phage	5.4e-07	96.7
WP_002355414.1\|454663_454972_+	zeta toxin family protein	NA	NA	NA	NA
WP_071623404.1\|455051_455480_-\|integrase	tyrosine-type recombinase/integrase	W6LMU7	Streptococcus_phage	5.8e-16	35.7
WP_002363039.1\|455524_456025_-	HAD family hydrolase	NA	NA	NA	NA
WP_002355416.1\|456029_456797_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002355418.1\|457283_457709_+	galactose-6-phosphate isomerase subunit LacA	NA	NA	NA	NA
WP_002345825.1\|457725_458241_+	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
WP_002363040.1\|458251_459184_+	tagatose-6-phosphate kinase	NA	NA	NA	NA
WP_002355420.1\|459186_460167_+	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_002290550.1\|460194_460512_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_002343085.1\|460511_462218_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_002290548.1\|462364_463771_+	6-phospho-beta-galactosidase	NA	NA	NA	NA
WP_002355422.1\|463793_464066_+	DUF3884 family protein	NA	NA	NA	NA
WP_002355424.1\|464086_464986_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_002363043.1\|465422_466031_+	zeta toxin family protein	NA	NA	NA	NA
WP_002384822.1\|465978_466257_-	recombinase family protein	NA	NA	NA	NA
WP_002363045.1\|466244_466565_-	recombinase family protein	A0A219Y912	Aeromonas_phage	5.5e-19	45.1
WP_002355428.1\|470182_471157_+	choloylglycine hydrolase family protein	M1H001	Paramecium_bursaria_Chlorella_virus	2.1e-24	31.6
WP_002364917.1\|471601_471907_+	hypothetical protein	NA	NA	NA	NA
WP_002363048.1\|471900_472428_+	hypothetical protein	NA	NA	NA	NA
WP_002380048.1\|472679_472862_+	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_025257711.1\|473547_474507_+\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
WP_002358517.1\|474683_474875_+	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_002364907.1\|474903_475440_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_148294544.1\|475714_479125_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_002364905.1\|479324_480533_+	YSIRK-targeted surface antigen transcriptional regulator	NA	NA	NA	NA
WP_002358522.1\|480662_481079_+	hypothetical protein	NA	NA	NA	NA
WP_002384835.1\|481303_482041_+	hypothetical protein	NA	NA	NA	NA
WP_170310355.1\|482086_482569_-	recombinase family protein	A0A1V0E035	Clostridioides_phage	2.9e-11	37.2
WP_002346915.1\|482971_484222_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.1e-114	62.1
WP_002384836.1\|484498_484759_+	recombinase family protein	NA	NA	NA	NA
WP_100815088.1\|484771_484978_+	hypothetical protein	NA	NA	NA	NA
WP_002363071.1\|485057_485876_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_002363072.1\|486031_486739_+	N-acetylmannosamine-6-phosphate 2-epimerase	NA	NA	NA	NA
WP_002363073.1\|486731_488234_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_002358535.1\|488244_488727_+	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_002358536.1\|489359_490124_-	YibE/F family protein	NA	NA	NA	NA
WP_002363074.1\|490110_491175_-	YibE/F family protein	NA	NA	NA	NA
WP_002358539.1\|491513_491687_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_002382844.1\|491708_492086_+	hypothetical protein	NA	NA	NA	NA
WP_002363076.1\|492137_492542_+	NusG domain II-containing protein	NA	NA	NA	NA
WP_002363077.1\|492735_493806_+	ammonium transporter	NA	NA	NA	NA
WP_002363078.1\|493908_495042_+	NAD(P)-binding domain-containing protein	V9VEY6	Lactococcus_phage	2.2e-06	26.7
WP_002370911.1\|496110_496422_-\|transposase	IS3 family transposase	A0A0N9SIX5	Staphylococcus_phage	1.6e-23	65.6
WP_002367939.1\|496527_496803_-\|transposase	transposase	A0A0N9S8A3	Staphylococcus_phage	1.1e-10	40.9

DBSCAN-SWA_3

851837 : 859757

Planktothrix_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355794.1\|851837_852896_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-17	30.1
WP_002355795.1\|852895_853852_+	ATP-binding cassette domain-containing protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	3.2e-06	23.9
WP_024797119.1\|853892_854963_+	helix-turn-helix domain-containing protein	A0A288TXV8	Enterococcus_phage	1.7e-88	49.0
WP_002355797.1\|855363_855885_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.0e-14	33.3
WP_002355798.1\|855998_856199_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_002355799.1\|856259_856619_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_002385048.1\|856664_857045_-	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_002358829.1\|857112_857472_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_002403715.1\|858050_858566_+	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	1.0e-38	48.8
WP_024797120.1\|858581_859757_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	2.3e-86	48.0

DBSCAN-SWA_4

907951 : 978858

Enterococcus_phage(88.0%)

capsid,portal,integrase,head,tail,holin,terminase,protease,tRNA

attL 908568:908595|attR 948012:948039

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355867.1\|907951_908296_+\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_002355868.1\|908308_908596_+	50S ribosomal protein L27	NA	NA	NA	NA
908568:908595	attL	NA	NA	NA	NA
WP_010784379.1\|908683_909838_-\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	2.2e-65	36.1
WP_002403734.1\|909906_910476_-	DUF3221 domain-containing protein	NA	NA	NA	NA
WP_024797130.1\|910656_911085_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_010716842.1\|911102_911516_-	helix-turn-helix transcriptional regulator	A0A0M4QX29	Bacillus_phage	3.6e-31	53.2
WP_002406956.1\|911749_911959_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010710745.1\|911962_912247_+	hypothetical protein	NA	NA	NA	NA
WP_010710744.1\|912261_912975_+	Rha family transcriptional regulator	D2IYT0	Enterococcus_phage	1.2e-87	75.8
WP_010710743.1\|912985_913171_+	hypothetical protein	D2IZW5	Enterococcus_phage	3.3e-24	96.7
WP_010710742.1\|913182_913386_+	hypothetical protein	NA	NA	NA	NA
WP_010710741.1\|913372_913855_-	hypothetical protein	M1PL51	Streptococcus_phage	1.4e-18	36.9
WP_024797131.1\|913948_914143_+	hypothetical protein	D2IZ57	Enterococcus_phage	3.0e-28	93.8
WP_002364222.1\|914133_914319_+	hypothetical protein	D2IZ58	Enterococcus_phage	3.6e-23	94.7
WP_002380444.1\|914362_914686_+	hypothetical protein	D2IYT5	Enterococcus_phage	7.7e-45	86.9
WP_002364220.1\|914685_914913_+	hypothetical protein	D2IZX4	Enterococcus_phage	8.6e-35	97.3
WP_002364219.1\|915010_915952_+	YqaJ viral recombinase family protein	D2IZK1	Enterococcus_phage	3.8e-177	99.7
WP_002364218.1\|915954_916845_+	recombinase RecT	D2IYT9	Enterococcus_phage	1.3e-163	100.0
WP_002372048.1\|916858_917821_+	DUF4373 domain-containing protein	D2IZR2	Enterococcus_phage	3.0e-169	100.0
WP_002368214.1\|917824_918127_+	hypothetical protein	D2IZR3	Enterococcus_phage	1.6e-47	99.0
WP_002372047.1\|918127_918427_+	MazG-like family protein	D2IZY1	Enterococcus_phage	1.3e-43	90.9
WP_024797132.1\|918435_918870_+	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	1.6e-58	80.9
WP_002368217.1\|918869_919055_+	hypothetical protein	NA	NA	NA	NA
WP_049825004.1\|919261_920017_+	SAM-dependent DNA methyltransferase	A0A2K9V411	Faecalibacterium_phage	1.3e-29	34.2
WP_024797134.1\|920166_920520_+	hypothetical protein	D2IYU9	Enterococcus_phage	6.1e-27	81.9
WP_002396632.1\|920516_920765_+	hypothetical protein	NA	NA	NA	NA
WP_024797135.1\|920776_921295_+	DUF1642 domain-containing protein	D2IYV1	Enterococcus_phage	4.6e-39	53.8
WP_002367271.1\|921429_921678_+	hypothetical protein	D2IZL5	Enterococcus_phage	1.6e-29	89.4
WP_002364337.1\|922067_922484_+	autolysin	D2IZL7	Enterococcus_phage	7.1e-67	97.8
WP_002366354.1\|923300_923534_+	hypothetical protein	NA	NA	NA	NA
WP_024797137.1\|923536_924871_+	ParB N-terminal domain-containing protein	D2IZZ5	Enterococcus_phage	5.0e-215	82.0
WP_002363360.1\|924908_925100_+	hypothetical protein	D2IZZ6	Enterococcus_phage	1.5e-24	95.2
WP_010783305.1\|925236_925425_+	hypothetical protein	D2IZZ7	Enterococcus_phage	7.4e-24	90.3
WP_002368225.1\|925444_926185_+	hypothetical protein	NA	NA	NA	NA
WP_024797138.1\|926231_927035_+\|terminase	small subunit of terminase	D2J000	Enterococcus_phage	1.2e-115	86.9
WP_025193021.1\|927006_928326_+\|terminase	PBSX family phage terminase large subunit	D2J001	Enterococcus_phage	9.3e-230	91.8
WP_033592159.1\|928343_929882_+\|portal	phage portal protein	A0A097BY86	Enterococcus_phage	1.9e-282	97.9
WP_002406644.1\|929886_930825_+\|capsid	minor capsid protein	A0A097BY50	Enterococcus_phage	1.0e-169	98.7
WP_002406645.1\|930825_931095_+	hypothetical protein	A0A0S2MYD1	Enterococcus_phage	4.2e-44	98.9
WP_024797140.1\|931190_931454_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	1.2e-43	98.9
WP_002406647.1\|931576_932176_+	DUF4355 domain-containing protein	A0A097BY91	Enterococcus_phage	2.7e-75	98.5
WP_002381655.1\|932188_933121_+\|capsid	phage major capsid protein	A0A1B1V000	Enterococcus_phage	8.7e-174	99.7
WP_002406648.1\|933194_933527_+\|head,tail	phage head-tail connector protein	A0A097BY55	Enterococcus_phage	1.6e-53	99.1
WP_002406649.1\|933523_933859_+	hypothetical protein	A0A097BYB2	Enterococcus_phage	5.9e-56	96.4
WP_002406650.1\|933833_934214_+	hypothetical protein	A0A0S2MYE9	Enterococcus_phage	1.9e-63	97.6
WP_002406651.1\|934210_934600_+	hypothetical protein	A0A0S2MYG3	Enterococcus_phage	1.9e-66	98.4
WP_002373072.1\|934615_935146_+\|tail	phage major tail protein, TP901-1 family	A0A097BY59	Enterococcus_phage	4.3e-93	99.4
WP_002406652.1\|935223_935682_+	hypothetical protein	A0A0S2MYH7	Enterococcus_phage	5.4e-76	98.7
WP_002404970.1\|935737_936088_+\|tail	tail assembly chaperone	A0A0S2MYH5	Enterococcus_phage	2.5e-57	100.0
WP_002406573.1\|936180_936438_+	hypothetical protein	C9E2K3	Enterococcus_phage	7.0e-41	100.0
WP_010784160.1\|936453_939861_+	tape measure protein	A0A0S2MYN1	Enterococcus_phage	0.0e+00	97.6
WP_002373078.1\|939861_940791_+\|tail	phage tail family protein	A0A097BY64	Enterococcus_phage	8.1e-172	99.4
WP_002406654.1\|940807_942826_+\|tail	phage tail protein	A0A0S2MYF5	Enterococcus_phage	6.9e-309	99.6
WP_002404974.1\|942826_943000_+	hypothetical protein	A0A0S2MYG7	Enterococcus_phage	2.3e-24	100.0
WP_080270838.1\|943005_945396_+	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	0.0e+00	99.6
WP_002406655.1\|945495_945900_+\|holin	phage holin family protein	A0A097BY69	Enterococcus_phage	1.6e-68	100.0
WP_024797141.1\|945883_946717_+	peptidoglycan recognition protein	A0A097BY70	Enterococcus_phage	4.6e-134	85.2
WP_002403783.1\|947295_947547_+	hypothetical protein	NA	NA	NA	NA
WP_002363390.1\|947567_947819_-	hypothetical protein	A0A097BYB1	Enterococcus_phage	4.6e-21	66.2
WP_002355869.1\|948239_948692_+	phosphate-starvation-inducible protein PsiE	NA	NA	NA	NA
948012:948039	attR	NA	NA	NA	NA
WP_002355870.1\|948762_949578_-	metallophosphoesterase	NA	NA	NA	NA
WP_002391500.1\|949749_950814_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_002355872.1\|950827_951148_+	MazG-like family protein	NA	NA	NA	NA
WP_002355874.1\|951480_951912_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002355875.1\|951904_952357_+	transcription antitermination factor NusB	NA	NA	NA	NA
WP_002355876.1\|952460_953306_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	9.7e-39	36.7
WP_002355877.1\|953315_954662_+	exodeoxyribonuclease VII large subunit	A0A160DEV2	Gordonia_phage	1.0e-29	32.8
WP_002364628.1\|954663_954894_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_002371528.1\|954893_955775_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_002364633.1\|955788_956604_+	TlyA family rRNA (cytidine-2'-O)-methyltransferase	NA	NA	NA	NA
WP_002358881.1\|956742_957192_+	ArgR family transcriptional regulator	NA	NA	NA	NA
WP_002394342.1\|957209_958883_+	DNA repair protein RecN	NA	NA	NA	NA
WP_002383399.1\|958974_959085_-	DUF4044 domain-containing protein	NA	NA	NA	NA
WP_024797142.1\|959152_960118_-	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_002383401.1\|960362_960755_+	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_002383402.1\|960988_961474_+	division/cell wall cluster transcriptional repressor MraZ	NA	NA	NA	NA
WP_002355891.1\|961488_962445_+	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_002358883.1\|962461_962869_+	cell division protein FtsL	NA	NA	NA	NA
WP_002391503.1\|962868_965097_+	penicillin-binding protein	NA	NA	NA	NA
WP_002355894.1\|965124_966090_+	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_002373622.1\|966112_967483_+	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_002355896.1\|967487_968579_+	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_002358888.1\|968587_969712_+	FtsQ-type POTRA domain-containing protein	NA	NA	NA	NA
WP_002355898.1\|969885_971208_+	cell division protein FtsA	NA	NA	NA	NA
WP_002355899.1\|971234_972467_+	cell division protein FtsZ	NA	NA	NA	NA
WP_002358890.1\|972483_973161_+	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_002383408.1\|973153_973819_+	cell division protein SepF	NA	NA	NA	NA
WP_002355902.1\|973847_974105_+	YggT family protein	NA	NA	NA	NA
WP_002355903.1\|974131_974914_+	RNA-binding protein	NA	NA	NA	NA
WP_002355904.1\|975065_975767_+	cell division protein DivIVA	NA	NA	NA	NA
WP_002387984.1\|976077_978858_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	8.6e-92	27.8

DBSCAN-SWA_5

1253437 : 1271118

Enterococcus_phage(42.86%)

holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002357859.1\|1253437_1255834_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.7e-19	24.1
WP_002360497.1\|1255858_1256209_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002382232.1\|1256491_1256977_-	toxin	A0A097BY56	Enterococcus_phage	4.4e-60	70.5
WP_002357856.1\|1257011_1257494_-	helix-turn-helix transcriptional regulator	R9QTP6	Staphylococcus_phage	1.2e-20	48.6
WP_024797195.1\|1257890_1258646_+	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	8.7e-31	56.0
WP_002363797.1\|1258664_1259507_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	1.4e-29	30.3
WP_002363798.1\|1259573_1259966_+	hypothetical protein	NA	NA	NA	NA
WP_002360491.1\|1259985_1260393_+	RinA family phage transcriptional activator	NA	NA	NA	NA
WP_002382237.1\|1260614_1261031_+	hypothetical protein	NA	NA	NA	NA
WP_002363800.1\|1261043_1261556_+\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	2.6e-34	48.7
WP_002363801.1\|1261588_1261948_+\|tail	tail assembly chaperone	A0A0F6N4J9	Staphylococcus_phage	5.8e-09	32.2
WP_002363802.1\|1261965_1262322_+	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	1.3e-08	33.3
WP_024797196.1\|1262322_1265256_+	membrane protein	W8EBC4	Geobacillus_phage	6.9e-15	41.2
WP_002363804.1\|1265257_1266184_+\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	1.8e-147	78.9
WP_002363805.1\|1266196_1267654_+\|tail	phage tail protein	C9E2K6	Enterococcus_phage	1.5e-175	47.8
WP_002363806.1\|1267686_1269456_+	hypothetical protein	A0A097BYA8	Enterococcus_phage	1.5e-142	63.9
WP_002357842.1\|1269479_1269875_+\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	2.8e-33	48.9
WP_024797197.1\|1269993_1271118_+	SH3 domain-containing protein	A0A139ZVY1	Enterococcus_phage	7.0e-77	44.3

DBSCAN-SWA_6

1409406 : 1451357

Listeria_phage(55.56%)

capsid,terminase,integrase,plate

attL 1409361:1409383|attR 1456872:1456894

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1409361:1409383	attL	NA	NA	NA	NA
WP_024797034.1\|1409406_1410633_-\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	1.2e-74	41.2
WP_024797035.1\|1411130_1412699_-	SIR2 family protein	Q38324	Lactococcus_phage	9.6e-24	25.1
WP_024797036.1\|1412772_1413369_-	hypothetical protein	A0A059T7Z1	Listeria_phage	2.4e-31	36.9
WP_024797037.1\|1413396_1413861_-	ImmA/IrrE family metallo-endopeptidase	R4IBK9	Listeria_phage	4.2e-20	35.8
WP_002386707.1\|1413881_1414205_-	helix-turn-helix transcriptional regulator	A8ATJ9	Listeria_phage	2.3e-17	66.7
WP_010714015.1\|1414370_1414556_+	helix-turn-helix transcriptional regulator	A8ATK0	Listeria_phage	1.9e-11	60.3
WP_002386709.1\|1414568_1414748_+	hypothetical protein	NA	NA	NA	NA
WP_024797038.1\|1414816_1415371_+	hypothetical protein	NA	NA	NA	NA
WP_002386711.1\|1415420_1415582_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002386712.1\|1415593_1415764_+	hypothetical protein	NA	NA	NA	NA
WP_002377591.1\|1415760_1415976_+	hypothetical protein	NA	NA	NA	NA
WP_002405802.1\|1416031_1416322_+	hypothetical protein	NA	NA	NA	NA
WP_024797040.1\|1416326_1418441_+	AAA family ATPase	A0A1L2K2K3	Aeribacillus_phage	5.8e-48	25.4
WP_002392045.1\|1418441_1419614_+	hypothetical protein	NA	NA	NA	NA
WP_024797041.1\|1419613_1420315_+	MBL fold metallo-hydrolase	A0A1L2JY21	Aeribacillus_phage	5.0e-49	42.3
WP_024797042.1\|1420326_1421091_+	DnaD domain protein	A0A1B0Y2R2	Lactobacillus_phage	7.5e-14	61.4
WP_010829909.1\|1421106_1421472_+	hypothetical protein	NA	NA	NA	NA
WP_024797043.1\|1421468_1421966_+	Holliday junction resolvase RecU	A0A1L2JY30	Aeribacillus_phage	3.7e-14	37.2
WP_024797044.1\|1421986_1422301_+	hypothetical protein	NA	NA	NA	NA
WP_024797045.1\|1422384_1423134_+	hypothetical protein	D2IZY3	Enterococcus_phage	1.3e-114	83.3
WP_024797046.1\|1423158_1423353_+	hypothetical protein	NA	NA	NA	NA
WP_002417168.1\|1423383_1423611_+	hypothetical protein	C9E2N4	Enterococcus_phage	1.3e-06	50.9
WP_002417170.1\|1423760_1424246_+	hypothetical protein	C9E2P0	Enterococcus_phage	1.2e-89	98.1
WP_024797047.1\|1424246_1424558_+	hypothetical protein	NA	NA	NA	NA
WP_002417172.1\|1424557_1424764_+	hypothetical protein	D2IZL5	Enterococcus_phage	9.3e-28	86.4
WP_002417173.1\|1424764_1424944_+	hypothetical protein	NA	NA	NA	NA
WP_002377564.1\|1425080_1425269_+	hypothetical protein	NA	NA	NA	NA
WP_024797048.1\|1425369_1425954_+	positive control factor	NA	NA	NA	NA
WP_024797049.1\|1426389_1426632_+	hypothetical protein	NA	NA	NA	NA
WP_024797050.1\|1426600_1427317_+	phage antirepressor KilAC domain-containing protein	C9E2M3	Enterococcus_phage	7.4e-72	59.9
WP_024797051.1\|1427410_1428073_+	hypothetical protein	NA	NA	NA	NA
WP_024797052.1\|1428129_1429398_+	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	1.6e-98	47.6
WP_002417178.1\|1429523_1429754_+	hypothetical protein	A8ATN7	Listeria_phage	2.3e-11	52.3
WP_024797053.1\|1429807_1430185_+	hypothetical protein	NA	NA	NA	NA
WP_010829916.1\|1430218_1430944_+\|terminase	terminase small subunit	NA	NA	NA	NA
WP_024797054.1\|1430924_1432361_+\|terminase	phage terminase large subunit	A5GYP8	Lactococcus_phage	8.4e-200	72.4
WP_033592142.1\|1433651_1434590_+\|capsid	minor capsid protein	A8ATG2	Listeria_phage	6.3e-39	49.7
WP_002377551.1\|1434582_1434747_+	hypothetical protein	NA	NA	NA	NA
WP_024797057.1\|1434803_1435091_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	1.1e-26	67.1
WP_010829922.1\|1435083_1435293_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_024797058.1\|1435305_1436406_+	DUF2213 domain-containing protein	A8ATG4	Listeria_phage	2.9e-83	57.2
WP_024797059.1\|1436408_1436879_+	hypothetical protein	NA	NA	NA	NA
WP_010733792.1\|1436899_1437781_+	DUF2184 domain-containing protein	A8ATG6	Listeria_phage	6.7e-83	52.2
WP_002377541.1\|1437800_1438187_+	hypothetical protein	NA	NA	NA	NA
WP_002377536.1\|1438198_1438540_+	DUF4054 domain-containing protein	NA	NA	NA	NA
WP_002386757.1\|1438539_1439142_+	hypothetical protein	D6PSY0	Lactobacillus_phage	9.0e-39	45.5
WP_002425320.1\|1439141_1439516_+	hypothetical protein	A8ATH0	Listeria_phage	5.6e-31	50.8
WP_024797060.1\|1439508_1439976_+	hypothetical protein	NA	NA	NA	NA
WP_002400011.1\|1439972_1441010_+	DUF3383 family protein	A8ATH2	Listeria_phage	2.9e-101	56.1
WP_002377526.1\|1441025_1441424_+	hypothetical protein	A8ATH3	Listeria_phage	6.6e-30	54.0
WP_024797061.1\|1441476_1441809_+	hypothetical protein	A8ATH4	Listeria_phage	8.2e-26	57.8
WP_002386764.1\|1441849_1441990_+	hypothetical protein	A8ATH5	Listeria_phage	3.0e-06	70.3
WP_024797062.1\|1441992_1447158_+	peptidoglycan endopeptidase EnpA	A8ATH6	Listeria_phage	1.1e-148	41.7
WP_002386767.1\|1447157_1447715_+	LysM peptidoglycan-binding domain-containing protein	A8ATH7	Listeria_phage	2.8e-34	43.2
WP_002377517.1\|1447724_1448087_+	hypothetical protein	A8ATH8	Listeria_phage	5.1e-29	46.6
WP_024797063.1\|1448087_1448918_+	hypothetical protein	A8ATH9	Listeria_phage	7.8e-65	45.8
WP_024797064.1\|1448917_1449250_+	hypothetical protein	A8ATI0	Listeria_phage	1.6e-21	50.0
WP_024797065.1\|1449249_1449597_+	DUF2634 domain-containing protein	A0A2H4J4S8	uncultured_Caudovirales_phage	2.9e-13	49.4
WP_024797066.1\|1449589_1450744_+\|plate	baseplate J/gp47 family protein	A8ATI2	Listeria_phage	5.6e-114	54.1
WP_024797067.1\|1450727_1451357_+	hypothetical protein	A8ATI3	Listeria_phage	3.1e-58	56.2
1456872:1456894	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1737670 : 1746314

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002364081.1\|1737670_1738243_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.2e-25	35.1
WP_002384439.1\|1738239_1739271_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	1.1e-55	44.4
WP_002384438.1\|1739272_1740712_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.7e-49	32.3
WP_002384437.1\|1740687_1742907_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.8e-146	39.9
WP_002364085.1\|1742903_1743578_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002357271.1\|1743578_1743830_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002357270.1\|1743843_1744557_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	4.3e-48	43.0
WP_002384435.1\|1744708_1745833_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002384434.1\|1745825_1746314_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.8e-19	42.0

DBSCAN-SWA_8

1783851 : 1822367

Streptococcus_phage(56.25%)

transposase,integrase

attL 1793073:1793097|attR 1798139:1798163

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002297659.1\|1783851_1785030_-\|integrase	site-specific integrase	S6C485	Thermus_phage	3.4e-29	30.5
WP_002297662.1\|1785132_1785444_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002360096.1\|1785792_1786038_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002297668.1\|1786031_1786433_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_002297670.1\|1787000_1788836_-	beta-galactosidase	NA	NA	NA	NA
WP_002330923.1\|1789007_1790270_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002360092.1\|1790407_1790632_+	hypothetical protein	NA	NA	NA	NA
WP_002298159.1\|1790628_1790793_+	hypothetical protein	NA	NA	NA	NA
WP_002298157.1\|1790886_1792179_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	3.9e-31	40.4
WP_002313174.1\|1792452_1792713_-	hypothetical protein	NA	NA	NA	NA
1793073:1793097	attL	NA	NA	NA	NA
WP_101495273.1\|1793317_1794479_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.0e-79	51.3
WP_077497620.1\|1794551_1794758_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	U5P429	Shigella_phage	2.0e-06	53.3
WP_002383094.1\|1794761_1794875_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_002297874.1\|1795027_1795423_-	aspartate 1-decarboxylase	NA	NA	NA	NA
WP_002287875.1\|1795435_1796284_-	pantoate--beta-alanine ligase	NA	NA	NA	NA
WP_002287874.1\|1796298_1797126_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	M4QNT1	Ostreococcus_lucimarinus_virus	5.4e-50	38.0
WP_002349114.1\|1797137_1797998_-	Rossmann-like and DUF2520 domain-containing protein	NA	NA	NA	NA
WP_002297866.1\|1799730_1801050_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
1798139:1798163	attR	NA	NA	NA	NA
WP_002285815.1\|1801046_1801700_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.0e-24	33.2
WP_002330916.1\|1803270_1804647_-	ABC transporter permease	NA	NA	NA	NA
WP_002298083.1\|1804646_1805303_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-22	32.1
WP_002298080.1\|1805312_1806590_-	ABC transporter permease	NA	NA	NA	NA
WP_002330914.1\|1806776_1807262_-	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_010706480.1\|1807417_1807768_-	hypothetical protein	NA	NA	NA	NA
WP_002369219.1\|1808072_1808360_+	hypothetical protein	NA	NA	NA	NA
WP_002360081.1\|1808360_1808588_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_002371002.1\|1808658_1809849_+\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_002298831.1\|1809953_1810865_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.3e-57	41.1
WP_002298830.1\|1810883_1811888_-	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	1.4e-121	66.3
WP_024797247.1\|1811884_1814008_-	conjugal transfer protein	A0A1S5SF30	Streptococcus_phage	1.8e-174	58.7
WP_024797246.1\|1814012_1816460_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	76.3
WP_002298826.1\|1816446_1816836_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	2.5e-42	66.7
WP_002383098.1\|1816887_1817628_+	hypothetical protein	NA	NA	NA	NA
WP_002360078.1\|1817634_1818471_-	abortive infection family protein	NA	NA	NA	NA
WP_002298823.1\|1818535_1819039_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	3.1e-56	61.2
WP_002298822.1\|1819051_1819273_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.5e-28	87.7
WP_002346915.1\|1819669_1820920_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.1e-114	62.1
WP_002330905.1\|1821051_1821186_-	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_002360076.1\|1821182_1822367_-	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	1.0e-142	62.1

DBSCAN-SWA_9

2191164 : 2215722

Streptococcus_phage(95.24%)

integrase

attL 2186501:2186517|attR 2224336:2224352

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2186501:2186517	attL	NA	NA	NA	NA
WP_002356683.1\|2191164_2192934_-	DNA helicase RecQ	M1PGQ0	Moumouvirus	2.9e-77	39.6
WP_002356682.1\|2193251_2195087_-	translational GTPase TypA	A0A1S5SF82	Streptococcus_phage	1.6e-17	36.1
WP_001291561.1\|2195343_2196561_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|2196642_2196846_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_000857133.1\|2197306_2197537_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000804885.1\|2197533_2197956_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_001227347.1\|2198460_2198814_+	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000336323.1\|2198873_2199041_-	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_000691727.1\|2199159_2201079_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	100.0
WP_001791010.1\|2201094_2201211_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224319.1\|2201455_2202388_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-171	100.0
WP_000769868.1\|2202384_2203386_-	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_000804748.1\|2203382_2205560_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000331160.1\|2205562_2208010_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000506270.1\|2207993_2208500_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|2208474_2208972_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|2209088_2209310_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000398284.1\|2209352_2210558_-	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_000879507.1\|2210580_2210733_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|2210735_2212121_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|2212149_2212536_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|2212551_2212866_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_002356680.1\|2213345_2214128_-	inositol monophosphatase family protein	NA	NA	NA	NA
WP_002356679.1\|2214128_2214407_-	UPF0223 family protein	NA	NA	NA	NA
WP_002356676.1\|2214456_2215722_-	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	1.2e-45	34.1
2224336:2224352	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2458228 : 2467969

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002385686.1\|2458228_2460412_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	3.1e-286	66.8
WP_002356379.1\|2460444_2461041_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	6.0e-51	56.4
WP_002362328.1\|2461085_2462204_-	DNA polymerase IV	NA	NA	NA	NA
WP_002356377.1\|2462329_2463088_-	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002356375.1\|2463071_2463734_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.7e-19	31.1
WP_002356373.1\|2463748_2464621_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	6.2e-81	57.6
WP_002356372.1\|2464733_2465081_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	8.1e-16	36.7
WP_002356371.1\|2465073_2465913_-	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002384059.1\|2466029_2466980_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.2e-34	33.0
WP_002356367.1\|2466981_2467311_-	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_002356366.1\|2467330_2467969_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.1e-54	53.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP004081

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection