CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP004369	Burkholderia pseudomallei MSHR520 chromosome 2, complete sequence	2 crisprs	cas3,csa3,DinG	0	0	5	0
NZ_CP004368	Burkholderia pseudomallei MSHR520 chromosome 1, complete sequence	2 crisprs	cas3,DEDDh,csa3,DinG,WYL	0	0	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP004369_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004369_1

1716418-1716503

Orphan

Consensus_repeat	Method
CGGAATGCCCGATCATCGGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP004369_1

>merge|NZ_CP004369|1|1716418-1716503|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGC

>NZ_CP004369|1|1|1716418-1716503|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGC	CTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGC
CGGAATACCCGATCATCGGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004369.1\|WP_043309283.1\|1712916_1715190_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NZ_CP004369.1\|WP_004187469.1\|1715322_1715718_-\|conjugal-transfer-protein-TraR	unknown	unknown	gnl\|CDD\|224648
NZ_CP004369.1\|WP_004530663.1\|1726161_1726611_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341411
NZ_CP004369.1\|WP_004523292.1\|1704486_1705719_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	unknown	unknown	gnl\|CDD\|223997
NZ_CP004369.1\|WP_004200700.1\|1707747_1708863_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378454
NZ_CP004369.1\|WP_161956516.1\|1728626_1729766_-\|porin	unknown	unknown	gnl\|CDD\|238208
NZ_CP004369.1\|WP_004542004.1\|1710112_1710703_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004369.1\|WP_004552281.1\|1727064_1727718_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NZ_CP004369.1\|WP_020850032.1\|1710968_1712627_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NZ_CP004369.1\|WP_004541915.1\|1718559_1720401_+\|ribonucleotide-reductase	unknown	unknown	gnl\|CDD\|180772
NZ_CP004369.1\|WP_004529498.1\|1727785_1728220_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NZ_CP004369.1\|WP_041188423.1\|1703437_1704481_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP004369.1\|WP_004523291.1\|1709161_1710097_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NZ_CP004369.1\|WP_004542030.1\|1717078_1718344_+\|polyhydroxyalkanoate-depolymerase	unknown	unknown	gnl\|CDD\|130908
NZ_CP004369.1\|WP_004523279.1\|1722839_1723871_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236122
NZ_CP004369.1\|WP_004541988.1\|1725828_1726158_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004369.1\|WP_004541936.1\|1723867_1725700_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223732
NZ_CP004369.1\|WP_004529483.1\|1706972_1707413_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NZ_CP004369.1\|WP_004536976.1\|1720475_1722287_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl\|CDD\|225098
NZ_CP004369.1\|WP_004541900.1\|1701984_1703436_-\|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl\|CDD\|237001

Protein	Function_ID	Function_description	E-value
NZ_CP004369.1\|WP_043309283.1\|1712916_1715190_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	5.46136e-57
NZ_CP004369.1\|WP_004187469.1\|1715322_1715718_-\|conjugal-transfer-protein-TraR	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.7869e-14
NZ_CP004369.1\|WP_004530663.1\|1726161_1726611_-\|CBS-domain-containing-protein	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	3.14402e-50
NZ_CP004369.1\|WP_004523292.1\|1704486_1705719_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	5.32689e-143
NZ_CP004369.1\|WP_004200700.1\|1707747_1708863_-\|hypothetical-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.16274e-11
NZ_CP004369.1\|WP_161956516.1\|1728626_1729766_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	2.50846e-54
NZ_CP004369.1\|WP_004552281.1\|1727064_1727718_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	4.23582e-20
NZ_CP004369.1\|WP_020850032.1\|1710968_1712627_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	5.49793e-37
NZ_CP004369.1\|WP_004541915.1\|1718559_1720401_+\|ribonucleotide-reductase	gnl\|CDD\|180772	PRK06948, PRK06948, ribonucleotide reductase-like protein; Provisional.	0
NZ_CP004369.1\|WP_004529498.1\|1727785_1728220_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	9.00264e-33
NZ_CP004369.1\|WP_041188423.1\|1703437_1704481_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NZ_CP004369.1\|WP_004523291.1\|1709161_1710097_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.07132e-61
NZ_CP004369.1\|WP_004542030.1\|1717078_1718344_+\|polyhydroxyalkanoate-depolymerase	gnl\|CDD\|130908	TIGR01849, unnamed_protein_product, polyhydroxyalkanoate depolymerase, intracellular. This model represents an intracellular depolymerase for polyhydroxyalkanoate (PHA), a carbon and energy storing polyester that accumulates in granules in many bacterial species when carbon sources are abundant but other nutrients are limiting. This family is named for PHAs generally, rather than polyhydroxybutyrate (PHB) specificially as in Ralstonia eutropha H16, to avoid overcalling chemical specificity in other species. Note that this family lacks the classic GXSXG lipase motif and instead shows weak similarity to some [Fatty acid and phospholipid metabolism, Degradation].	2.48008e-114
NZ_CP004369.1\|WP_004523279.1\|1722839_1723871_+\|hypothetical-protein	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	3.7258e-30
NZ_CP004369.1\|WP_004541936.1\|1723867_1725700_+\|STAS-domain-containing-protein	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	2.72698e-107
NZ_CP004369.1\|WP_004529483.1\|1706972_1707413_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	1.19676e-25
NZ_CP004369.1\|WP_004536976.1\|1720475_1722287_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl\|CDD\|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	2.74988e-74
NZ_CP004369.1\|WP_004541900.1\|1701984_1703436_-\|2-oxo-acid-dehydrogenase-subunit-E2	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	2.33754e-132

>NZ_CP004369.1|WP_004187469.1|1715322_1715718_-|conjugal-transfer-protein-TraR
MAAFDEHQLQVLGALLRACRQALQADVRAGERQRADEPYANLAGPAPDEGDEANADLFVDVDHALLGMKLAELRDVDAALQRIARRDYGCCADCGQPIAYERLLARPTALRCAPCQRAHERRFATQPRPSL
>NZ_CP004369.1|WP_043309283.1|1712916_1715190_-|FAD-dependent-oxidoreductase
MREFGYLLVGGGIASVTAARTLRGEDASASIAILCGEPVLPYQRPPLSQEWLMGAVQPASITLHDAAFYAAQRIDIALGVRAEQLDRAKRIVRTSSGATFRYGKLLIATGASAKAPALPGFGLDGVHVLHTFAQAQALKDAAAHARRATVLGGGFLGVEIAATLQALGLQVTLVERAPGVMPSLRAPALGGHFEALCRARGIDVLTRCEVRRVLGAQCVEAVETSDGGTRPCDLFVAAVGVTPNCGWLDGSGLALGDGVEVDAFLQTADPNVFAAGDVAHFDDPIFGVRRRIEHWDNAVRQGRIAARNMLGHRLPYRDVSIFYGSVFGLSYNLLGYPVGATETIERGAFDEASYMQLYLADDVLRAAFTIDRPAVEIAALNDAIRLHVNVAAHKMKLSDPNYPLDKLPVQTILILQGGGALGAFECGAVKALEQHGVRPDVISAVSIGAFNGAIVASHPKGATKALEAFWRELSIALPLPYESQWREAWLSSYVLSFGVPNFLKPQWSQLGFDADRLRAKWTSFFDATAIEQLIARYVDFDSLGMSPTRLLIGAVDVETGEPRIFDSYVDRLSPAHVLASGSLPPGMPWTVVDGRPYWDGGVVSNSPLDLVIARCGQIGGRVFIVDLFSGSKALPTNLVEVMLRREEIAYMDRVRNDLRFEEYASDFRDLVDGILAHVDAPSANEIRQQPLYIRLMGNRAAIDIARITLNREGRLSFIEDYDFSSDAIAQLQQQGYDAALVALANGRSRRRRGRRRA
>NZ_CP004369.1|WP_020850032.1|1710968_1712627_+|GMC-family-oxidoreductase
MKQQSYDYDYVVVGSGFGGSVSALRLSEKGYRVLVIEQGRRWTPENLPESTWNLSRWQWRPALGLRGFFSMRFFRHVVVLHGNAVGGGSITYANTLLVPPDKVWREGTWAGLEDWERVMPAHYATAKRMLGVVTNRRMDAADFRLKDMAKLIGVEKSFYPTEVGVFFGDDADAPGTRYADPYFGGAGPERTSCIGCGGCMVGCRHGAKNTLDRNYLYLAERLGAQVREQTKVVDVRPLDARADGAAGYAVEAVSLAAGARGAKSRLTCRGVVFAASSLGTQDLLMRLKEKGSLPRLSDALGKRVRTNAESLIGVRFPKSRVDLSKGVAIGSGIYIDEHTHIEATRYPSGSDTMGLLTTVLTRGAPGGLRVLVWLGALAKLVLTRPLSAWQMIVPRGFARETMIFLCMQTLEGHLTMRLKRRWFWPFSKQLATSGAKIPAYIPAANDFAQKAARALGGVPMTSLTEILLNVPMTAHCMGGAAMARDARDGVCDGRSRVFGYRNMYVCDGSVLGANLGVNPSLTITALAEHAMSHVPAAREQRWDSTAETPVAA
>NZ_CP004369.1|WP_004542004.1|1710112_1710703_+|hypothetical-protein
MCRARGIGRQARGNATAPSPIAAAAIGARPRSAPRGPRISDAGRLAAARSAFAIHQERRKRNADRHGTHPYDADSRAAPREAPRFEHEPKKQRDAAQHEVDRDRAAREIRERIEHKARPDVRRAERPISQDVAQTPIGAAGAISPSTAHSIFLEIGLALAGRPIQVRRNRAPFTHGTPRRRPARGPTARTASPAPV
>NZ_CP004369.1|WP_004523291.1|1709161_1710097_+|LysR-family-transcriptional-regulator
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCDEHAPA
>NZ_CP004369.1|WP_004200700.1|1707747_1708863_-|hypothetical-protein
MTQDVTVFRARYRASVHPRYNAWLHGGFVLAYGCAAIAFFLKDVARVSAVQWASVPAAFLLFNWLEFTVHRHVGHVKRRFGAMFYRRHTGDHHSFFANEQIAYREARDWRVILFPAWLIVVFSLGLFALHAVLGRFDANVAGLFASTMLGGYLLYECVHACEHLPDAHPLAKWPWIRQMRVLHRVHHRDALMRSCNFDVIWPLMDWLHGTLRWSEAPGADMSTRMRHEIDIACAGADVLAYASDASRWPEWHPSSLRVDGPAGSLAAGSRFDEDVRAAGRVDRLHWDVVRNEPGVMWQARAANTAGSLRILLTYECSGGPRGARFVRTLHYHSPNPLLRLANALVMRGRVERESAYSLTLLKRRLEAARDA
>NZ_CP004369.1|WP_004529483.1|1706972_1707413_+|SRPBCC-family-protein
MKQQRIEIAEEFDAPVHQVFRFFSEHENLKSIFSPAKIRRISDGEPARNGVGSAREMRVPGAPPFVETVTAYQENELIEYRITRGSPLRDHLGVMRFVPIDEHRTYFHYVITFEGKVPFVAPVVRHVLEGSIRRGLGKVATRRLWG
>NZ_CP004369.1|WP_004523292.1|1704486_1705719_-|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha
MSQYGPLRLHVPEPTGRPGCKTDFSYLRLSPAGKVRKPPIDVAPADTSDLAYGLVRVLDEHGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHTLALERGDMCFPTYRQQGILMVREYPLVDMMCQLMSNERDPLKGRQLPVMYSTRDAGFFSISGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVVNNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPTLIEWVTYRAGPHSTSDDPTKYRPGDDWTNFPLGDPLERLKRHMIGIGVWSEQDHEDTKAALEAEVLAAQKEAERYGTLADEHVPNVASIFEDVYKEMPAHLRRQRQQLGV
>NZ_CP004369.1|WP_041188423.1|1703437_1704481_-|alpha-ketoacid-dehydrogenase-subunit-beta
MTTASKEGPAAPPMTMIQALRSAMDVMLERDGNVVVFGQDVGYFGGVFRCTEGLQNKYGKSRVFDAPINEGGIVGAAVGMGAYGLRPVCEIQFADYFYPASDQIVSEAARLRYRSAAEFIAPLTIRMPCGGGIYGGQTHSQSPEAMFTQVCGLRTVMPSNPYDAKGLLISAIENDDPVIFLEPKRLYNGPFDGHHERPVTPWSKHPASLVPDGYYTVPLDSAAIVRAGGDVTVLTYGTTVHVSLAAAEETGIDAEVIDLRSLWPLDLDTIVESVRRTGRCVVVHEATRTCGFGAELIALVQEHCFHWLEAPVERVTGWDTPYPHAQEWAYFPGPNRVGDALRRAMEN
>NZ_CP004369.1|WP_004541900.1|1701984_1703436_-|2-oxo-acid-dehydrogenase-subunit-E2
MGVHVIKMPDIGEGIAEVELGLWHVKVGDRVKEDQAIADVMTDKASVEIPSPVTGVVVALGGKEGDVLAVGSELVRLEVEGDGNHKAEPDGGARVAAAQPERVADTAHAHASAAAKSARGEHGAGHGRDDARAASSGTSSGASHTQHAEREARGHRESSEYREDRSVSRGASQTDVERGPASPPPARRPGERPLASPAVRKRAWDLGVELRYVHGTGEAGRILHEDLDAYLQGRGAAAQRARGGQAAYVERHDEEAVPVIGLRRKIAQRMQDAKRRIPHFSYVEEIDVTELEALRAELNRKYGDTRGRLTVLPLLARAMVIALREFPQINARYDDEAGVVTRHGAVHLGIATQSKAGLMVPVVRHAEARDPWSIAAEVARLADAARAGRAERDELSGSTITITSLGALGGIASTPVINSPEVGIVGVNRIVERPMFRGGAVVARKLMNLSSSFDHRVIDGMDAAEFIQAVRGLLEQPALLFVE
>NZ_CP004369.1|WP_004542030.1|1717078_1718344_+|polyhydroxyalkanoate-depolymerase
MLYAWLEAQREFFRTCQPWAGAAQRAGAGARPAGWPTWGPMARAADAVPAPPSFAIASIEIDGAAVPVDECVVDDTPFCALRKFSRRLRGDAAARPAVFLCTPLAGHHAVMLRETVETILATRDVYVTDWRNARDVPLEAGAFGLDDYVCTLERFVAGAAGDGLHMMAVCQATVPALAAVALLAARDVHVTSVALLGGPVDTRSHPTLIDRFALEHDLDWFRRTAIDIVPPPYAGAGRRVYPGFIQHAAIIVAHPQRRASLESRYWAAWMTGDFAAAARCLREMNEYGAVLDMTERYFLDTIRVIFHERLLAQGRWSIGRRLVAPQRLTRTALCTIEGGRDDIAGAGQTHAAHALCDAVPDAVRERITEPDCDHYDLFLGPRWRRTIHPALDAFWTRAEAARAAAGEPRPTAERAERRIAH
>NZ_CP004369.1|WP_004541915.1|1718559_1720401_+|ribonucleotide-reductase
MRTINKRTRTIAHADSFVRMIGDMDDQPICDAVFADRYALPGEHSRAQACARVARALALAEPMATRSGAARRFYRNLLNGAFGAGRIMARAGAAPDQTMASCFVHPIRAPAALTRFHPNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALPGADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGRERIGATSPCGAQPLPPYGSAMLGAIDLSRFVRNPFGAGGEPRFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYITSDLRHHAYAASAELAAERGAYPLCDRHAHLDALRAGPPLPHAVCHAIERDGLRHSHLTSFAPVIGVSLAFGDHCSPGIEPARAWIEHRPVRAGAAGAPGMRAENHAHRLFRSLRGERAALPDYFATDADVAPGERLAMRVALQPYVDAGIDNTLTLANHYSLEEVNALLFAAWRAKLKSVAIRRADLARDAQPSDDDGV
>NZ_CP004369.1|WP_004536976.1|1720475_1722287_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MTTGAVAARRLPRRGTARGRRAPSRAFTIHGGDEMRRSRPPKPAKPAAVRRRPHGAARAHAIRGNGPQRRAVRERAARRLSRDIDAALRRASTYPHPAGPIVRIETHLSVVYLVGRFAYKRLKPFDFGFANFSELAARRRACEAELALNRPLAAPIYLAAGPLVRRARGLRLFGAGAAVDHVVRMRRFDERMLFSRLLARGALDAADIDAAATRLAAYHLHAPRDIPRRAYGSARELRRQLDDMLAPLARALGAALPASLRAWCVRRCDELAAHLDARRADGYVRACHGDLHLNNVVKRGRDALMFDCIDFDDALRWIDVINDLSFLLMDLHAHDRAALAHRLLNRWLDETGDFAGLAALPLYVAYRALVRALVATMRAGGDAAARAARIERARRYVDVAAHAARARRPCLLLCHGYSGSGKSVASRALADVSGAIRLSSDSERKRARPFAAVDARPLPASAYTPQQIDAQYERLRALARDVLRAGYTALVDATFLSHARRARFFALARELGVPVYVLDFHASRACLERRVDARAAARDDRSDAGAAVLATQRASADPLDADERARTIGFDTDVPLATLRSAGYWRPVLDALDAARVDAQATR
>NZ_CP004369.1|WP_004523279.1|1722839_1723871_+|hypothetical-protein
METSPLKTTTPEAIPPFDPSASVEDKLRLAIHYAILAPSSHNTQPWRFMVGDGSVMLCADRLRALSVVDPYDRELLISCGAALLNLRVALSRFGFAYVIDMFPSPSDPDVIALVRLDPHGYHDESLVPLFDAILERVTTRTPYANEAVPCDVQRALVDAGAAEGAEIACVDAPHALDEIAELIADADRLQFADPRFRRELANWVHPRRHDDGMPAFAAGVPALLDFATPVVASAIRTFDLGGGLAAMHHKLVDGSPLIVGISTASDDRDAWVAAGQALERVLLVAAAAGLTASYLNQPIEIDALRERLRPLLHVDAHPQLLLRIGRGPVVAHAPRRPLMDVVS
>NZ_CP004369.1|WP_004541936.1|1723867_1725700_+|STAS-domain-containing-protein
MTERERAARGHNDARRGGGDSGGDDEAWRRWLPGIATLRTYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGASIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQHDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLVAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRHPGAALTRGLVAFRWDAPLFHANATIFRDHVRDAIAEAGAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>NZ_CP004369.1|WP_004541988.1|1725828_1726158_-|hypothetical-protein
MLSSRLVSSRLAPCCVYIDIQGEGDVDVDAEGNGNGNIDVIDSKRCEPSGVEPIERAVRRPRYRAQSGCLSGIHRNGIVMPDPMPPTNRFDRLRASAVIVDRTKPRRSP
>NZ_CP004369.1|WP_004530663.1|1726161_1726611_-|CBS-domain-containing-protein
MNAAEICTREVVACRRTDTVLDAAHLMRDRHVGDLIVVDDAGHAHAPVGMLTDRDIVLSLIAKDVDPAALFVGEIMSAPAAVVHEHDSLWTIAQRMRLTGVRRMPVVNADGALVGMVSVDDLLASVAALFDEIASISRRQIHFEEKARD
>NZ_CP004369.1|WP_004552281.1|1727064_1727718_+|SagB/ThcOx-family-dehydrogenase
MSDPELLTYQPIAVALPGPAEAGAPAVIDLPPPDLGAGLPLMSALSLRASTREFSSAALAPTTLGELLWAADGVNRPTTGGRTAPSAHAFNEIDVYAALPDGVYRYDAALHRLLLKHAVDARNLTGYQDFVGAAPLDLIYVVRMSRLLSMPKPLRETFSAVAAGAIAQNVALYCASTGLGCVVRGWINHRLLAEALSLNEDELPILAQTVGKPAAHP
>NZ_CP004369.1|WP_004529498.1|1727785_1728220_-|Hsp20/alpha-crystallin-family-protein
MSNVTRYDPFSLEPVSDLFQGLFRPLRGIADADDEKLASMKIDVTENDQAYAVKAELPGVDKNDINVQIDGNTVSISAKVERNKELKEGERVIRRERYSGEFARTFSLANELDRDAASAQYQDGVLSLTLPKKASSEKKKLTIG
>NZ_CP004369.1|WP_161956516.1|1728626_1729766_-|porin
MGDVMNAKSIAAAALAVAQAGLAHAQSSVTLYGALDAGVLWQNTSAASFSPTAPNTGAVVRFKDGGVYSSLWGIKGTEDLGGGYRVNFRLQGAFDGGTGKFGLSDAPGAVAAFNQIATLGVSGPFGTFNAGRQIVPMIYAMADTDVRAARFFGSVLTAWLGLNTAAGWPGNSTNAPIGALYDSDALVYQSPAFGGALLALEYAPGGVPGGVQRGARASIVLKYASNALNLAAVYYNGHDTNPAPGASATGLDNNRFVYVGAQYKLKDVAVSASYGNGRNPARGDRVNLDMFAFGLGYRVSPFFRVSSGVYYLKDRNRSANRSTSIVLGADYELSKHTTLYAQGGRVDNRGTMAQMLAYGQPVAPGLATTAAMLGMRHSF

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Crispr_ID: NZ_CP004369_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004369_2

3316197-3316361

Orphan

Consensus_repeat	Method
GCGAGCGCGGCGAGCGCGGCCGCG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP004369_2

>merge|NZ_CP004369|2|3316197-3316361|PILER-CR
GCGAGCGCGGCGAGCGCGGCGGACAGGCCGCTCGCGACATAGCTCGACGCGACGTAGCGGCGCGCGTCGACGCCCGCGGCGAGCGCGGCCGCGCGATGGGCGCCGAGCGCGTGCAGCGCGAGCCCGTAACGGGTGCGATGGGCGAGCGCGGCGAGCACGGCCGCG

>NZ_CP004369|2|1|3316197-3316361|PILER-CR
GCGAGCGCGGCGAGCGCGGCGGAC	AGGCCGCTCGCGACATAGCTCGACGCGACGTAGCGGCGCGCGTCGACGCCCGCG
GCGAGCGCGGCCGCGCGATGGGCG	CCGAGCGCGTGCAGCGCGAGCCCGTAACGGGTGCGATGGGCGAGCGCG
GCGAGCACGGCCGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004369.1\|WP_004542822.1\|3314940_3315921_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119321
NZ_CP004369.1\|WP_004542736.1\|3307647_3308472_+\|anti-sigma-factor	unknown	unknown	gnl\|CDD\|227949
NZ_CP004369.1\|WP_004542817.1\|3323445_3324909_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP004369.1\|WP_004542797.1\|3309911_3310139_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004369.1\|WP_153260263.1\|3319935_3320364_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	unknown
NZ_CP004369.1\|WP_004206353.1\|3320526_3321219_+\|isoprenylcysteine-carboxylmethyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224931
NZ_CP004369.1\|WP_004524124.1\|3321966_3323226_-\|monooxygenase	unknown	unknown	gnl\|CDD\|173852
NZ_CP004369.1\|WP_004528277.1\|3309555_3309915_+\|lipoprotein	unknown	unknown	gnl\|CDD\|226765
NZ_CP004369.1\|WP_004542824.1\|3312049_3314722_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|273805
NZ_CP004369.1\|WP_004199294.1\|3307129_3307651_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|237123
NZ_CP004369.1\|WP_004542789.1\|3318797_3319808_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380528
NZ_CP004369.1\|WP_004542841.1\|3308529_3309516_+\|YceI-family-protein	unknown	unknown	gnl\|CDD\|377274
NZ_CP004369.1\|WP_162473170.1\|3306358_3307114_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004369.1\|WP_004524117.1\|3310918_3311923_+\|FecR-family-protein	unknown	unknown	gnl\|CDD\|236622
NZ_CP004369.1\|WP_004542732.1\|3316995_3318801_-\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP004369.1\|WP_004542826.1\|3326662_3328057_-\|heavy-metal-sensor-histidine-kinase-IrlS	unknown	unknown	gnl\|CDD\|273593
NZ_CP004369.1\|WP_004524130.1\|3326286_3326559_+\|DUF4148-domain-containing-protein	unknown	unknown	gnl\|CDD\|379321
NZ_CP004369.1\|WP_009976571.1\|3321552_3321804_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004369.1\|WP_004542798.1\|3310412_3310922_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|171561
NZ_CP004369.1\|WP_004198472.1\|3325383_3325632_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP004369.1\|WP_004542822.1\|3314940_3315921_-\|ABC-transporter-permease	gnl\|CDD\|119321	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.	3.68045e-52
NZ_CP004369.1\|WP_004542736.1\|3307647_3308472_+\|anti-sigma-factor	gnl\|CDD\|227949	COG5662, COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription].	1.15709e-18
NZ_CP004369.1\|WP_004542817.1\|3323445_3324909_-\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.40707e-36
NZ_CP004369.1\|WP_004206353.1\|3320526_3321219_+\|isoprenylcysteine-carboxylmethyltransferase-family-protein	gnl\|CDD\|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	8.15398e-14
NZ_CP004369.1\|WP_004524124.1\|3321966_3323226_-\|monooxygenase	gnl\|CDD\|173852	cd01163, DszC, Dibenzothiophene (DBT) desulfurization enzyme C. DszC is a flavin reductase dependent enzyme, which catalyzes the first two steps of DBT desulfurization in mesophilic bacteria. DszC converts DBT to DBT-sulfoxide, which is then converted to DBT-sulfone. Bacteria with this enzyme are candidates for the removal of organic sulfur compounds from fossil fuels, which pollute the environment. An equivalent enzyme tdsC, is found in thermophilic bacteria. This alignment also contains a closely related uncharacterized subgroup.	3.81867e-137
NZ_CP004369.1\|WP_004528277.1\|3309555_3309915_+\|lipoprotein	gnl\|CDD\|226765	COG4315, COG4315, Uncharacterized protein conserved in bacteria [Function unknown].	2.7211e-31
NZ_CP004369.1\|WP_004542824.1\|3312049_3314722_+\|TonB-dependent-receptor	gnl\|CDD\|273805	TIGR01783, Ferrienterobactin_receptor, TonB-dependent siderophore receptor. This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	7.67057e-87
NZ_CP004369.1\|WP_004199294.1\|3307129_3307651_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|237123	PRK12511, PRK12511, RNA polymerase sigma factor; Provisional.	2.21088e-40
NZ_CP004369.1\|WP_004542789.1\|3318797_3319808_-\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380528	cd06305, PBP1_methylthioribose_binding-like, similar to methylthioribose-binding protein of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily. Proteins similar to methylthioribose-binding protein of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. The sugar-binding domain of the periplasmic proteins in this group is also homologous to the ligand-binding domain of eukaryotic receptors such as metabotropic glutamate receptor (mGluR), DNA-binding transcriptional repressors such as LacI and GalR.	1.21406e-120
NZ_CP004369.1\|WP_004542841.1\|3308529_3309516_+\|YceI-family-protein	gnl\|CDD\|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	4.12408e-28
NZ_CP004369.1\|WP_004524117.1\|3310918_3311923_+\|FecR-family-protein	gnl\|CDD\|236622	PRK09774, PRK09774, fec operon regulator FecR; Reviewed.	2.1512e-74
NZ_CP004369.1\|WP_004542732.1\|3316995_3318801_-\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	1.15905e-177
NZ_CP004369.1\|WP_004542826.1\|3326662_3328057_-\|heavy-metal-sensor-histidine-kinase-IrlS	gnl\|CDD\|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	0
NZ_CP004369.1\|WP_004524130.1\|3326286_3326559_+\|DUF4148-domain-containing-protein	gnl\|CDD\|379321	pfam13663, DUF4148, Domain of unknown function (DUF4148).	9.38719e-09
NZ_CP004369.1\|WP_004542798.1\|3310412_3310922_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|171561	PRK12528, PRK12528, RNA polymerase sigma factor; Provisional.	4.99978e-71

>NZ_CP004369.1|WP_004542822.1|3314940_3315921_-|ABC-transporter-permease
MRDATDRLSRLAALGALAAVLAFFAVAAPGFATLANVERVLVNHFALLAIAALGMTLALSIGAIDLSLGTAIDVASLAFVCALAHRAGCASAALAGLGAALALGAANALLVTRLGIAPFLATLGTLFIGQTIQQLATDGGQPIYLLSTAPPPAFDALAHGVWLGVAAPLWIVAALAGALHVALERSTLGRQARALGAQPGVARHSGLRVGALAAGVFVASALVYGVAGLVLSSTVRSYAPQAGNAYLLNAIGATFIGATLSEARRPNVAGTLLGVLLVSFVANGLLLIGWNFYWQQVASGALVFAVLALGSGVGRERRARDAGQSG
>NZ_CP004369.1|WP_004542824.1|3312049_3314722_+|TonB-dependent-receptor
MDSICNRRPHRAHAGVCADTANAPAGLPEAAQPAARLGAGRPRDAAAPRCARQATSHTSHASHTLHAPCMPQFAPQFAPRRVAPRRVVARVAAAALFSACAAPGVSGAAEPAAATRGYDIPAGSLDAALTRFGREAGILLSFPGELTTGLRSPGLHGRADPAAALDRLLTGTGLVALRQPSGGYTLARLPGPAAAGADAALAADTTLPTVAVRASGPHADSYRPPREAAGLRSDAPLAEVPQAVAIVAQQVLRDQRPRNLDDALANVSGITQGNTLGSTQDTVMKRGFGDNRDGSVMRNGMPIVQGRSLNATTDSVEVLKGPASLLYGIMDPGGVINVVTKQPQLARRHAISALGSTYGGGRNGGELTFDSTGAIGESRVAYRLIVDQTNEQYWRNYGEHRETLVAPSLAWYGRDTQVVLSYEYRRFLMPFDRGTALDPRTNAPLAIPARRRLDEPFNDMRGESNLAQLAIDHQLAPDWKVHVGYSYNRETYDANQIRITAVDPLKGTLTRSNDATHGSRSTDSYGIAYVDGRVTLAGMRHDVQFGVDGEYRQVYRADMLRQPIKTPFSYLNPTYGLVPPSTSVSASDSDQSDTLHTASLFFQDSIHLSERWMLVGGARWVRYSQLAGRGRPFQVNTNLSGTKWLPRAGIVYKWNDALSLYGSYTQSLKPTSKIAPMAGGYVIDGSTAPEEGASWELGAKLDMPGGLAGTLAFFDIDKKHVLVSQYDDATNQTAWRTSGRARSRGIELDVSGRIGARWNVIASYAYIDAKTTEDPLYAGNRLWNVARHTASLAAVYDVGTVLGGDDLRIGAAGRYVGARPGDSANSFTLPAYATADAFATYDTRLGKQKLQFQLNVKNLFNRTYYPSSVNRFFVSVGDARQVSLLTTLQF
>NZ_CP004369.1|WP_004524117.1|3310918_3311923_+|FecR-family-protein
MSGAKPAGGPPAVPERVARRAVQWWVELGAAPASDATRARLARWRAEHPAHDAAWRHIEAVNGRLGHVASALSARAARAALLPPRSRGRRAALKALAVLLFAGGGAWTGQAYLPWRAWGADVRTALGERRTITLADGTTVVLNTDTAIDIRFDDATRGVRLLRGEIMVTSGRDAARAVPRALVIATAHGDVRPVGTRFSVRERGDATRVDVFDGAVRIAPRRAVGRAPLITAGHGADFTRDALAGPPRVLGASAGAWVDGILVASNLRLADLLAEIDRYRPGRVRCDAAVANLRVSGTYPLDDTDRILDTLRETLPVDVEYLSRYWVTVVAARD
>NZ_CP004369.1|WP_004542798.1|3310412_3310922_+|sigma-70-family-RNA-polymerase-sigma-factor
MPANTLRLQREIAALYTGHRGWLHGWLSKKLGCGERAADLVHDTFIRLLARDEPIDAAEPRAFLTTVAQRVLYNHWRRERLERAYLDALAQWPEAVAPSPETRAVLFETLVEIDRMLDGLPAVVRRAFLLAQLDGMTHAQIAAELRVSLATVKRYLVKAGAQCYFAIAA
>NZ_CP004369.1|WP_004542797.1|3309911_3310139_+|hypothetical-protein
MTGKGGAAANSRAATAIVVAASGSISPASRRTALSTMKTTANATARRRDGGTMKAPKEPIASGGAVLAGSVESPV
>NZ_CP004369.1|WP_004528277.1|3309555_3309915_+|lipoprotein
MIRNVLIALVCAAPVAALAEPPKAAGGMIVDDDGMTLYTFDRDTMPGKSACTGGCTANWPAALADAYDKPGGDLGFIAAAGGKHQWTYKGRPLYRFSGDAKPGQHTGDGFGGMWHVARP
>NZ_CP004369.1|WP_004542841.1|3308529_3309516_+|YceI-family-protein
MDAAGSFASFAATLACALSAWLAPSAGIAQTAWPPDAPRVAGASGPPRTPGLARTPAAVTDAPGAATAGALAASPPAATRYRLDPRHSGVTFRVDNFWHAHLTMRFARMRAELSDVGDDRLASRVDVTVDAASLGANVPFVAALVKGSAMLDVARYPEIRFVGTRFERTGATTGVLTGELTIRAMTRPITLAVRFDAGRQLEPDTGARAEREGDESGESGESNPAERRAGQGRRAAELRDGRPRDAGPGVADSRDAMRRETDSGSAHRGAEPPERIARAAPDAARPLAFVADGHFSRTAFGLSRWLPAVGDDVRLRIRAEFVRARADP
>NZ_CP004369.1|WP_004542736.1|3307647_3308472_+|anti-sigma-factor
MSDDPDLCVAPESDEPGLLALSAFVDGELPDAQSRAMARRLASDPRAAGIAAHYRAQRAALRALFADPVATRHGPCVAWPVRTPWWRRAAFAGGALAAGVALGWLGGALAPRFAPSAALQWVAPAAAQRAFARDADLAYALYAPDARHPVEIAVGRDGAPLAWLSARVGRRIAAPSLREYGFALLGARLLPGAGGPAAQFMYENAAGERLALYVSASAQREAAVRPWRDGGRHTFYWVSERTAYALSGQLDEGRLRTIAADVCGELGGHPQRWR
>NZ_CP004369.1|WP_004199294.1|3307129_3307651_+|sigma-70-family-RNA-polymerase-sigma-factor
MSFESDVVGWLPQLRRYARALTGDPAWADDLVQDTVERAFSRMRAFRPDSNLRAWLLTILRHLYIDQLRARREFAVDDDEGPWRTLEAPAGQIDALVLRDVQRMLYRLPLEQREVLLLVCVEELSYQDASAVLGVPVGTVMSRLSRARERMRALLTDAPLRPPLSLTAARHHR
>NZ_CP004369.1|WP_162473170.1|3306358_3307114_+|hypothetical-protein
MVELSLKTRGQGRGGGANEFGRRAPAIVRCARSDGRRFAAASRRREPPRRGLRPDAREGLSDIDRHGENRLPAACRLPPAAYRLSLIAYRLSPAVRRGTPAARRSHPGAGRRTIAHRARRAGTLAGIPAYRHTGIPACPRPPQRFPPREKRANPPIFVMSPCEARNKTRAAFVFIHMGRRPPRRARDARPRPMRRPEAEMESIRMLSAACALLALMLAAGCASPGDMSPSDHAAPMGGYGRGGGSGGGGGY
>NZ_CP004369.1|WP_004542732.1|3316995_3318801_-|sugar-ABC-transporter-ATP-binding-protein
MKAALTTAAASAAAAPDAAGAPLALDVRRVVKRFGGVAALRGASLAVTRGTVHGLIGQNGAGKSTLVKLLAGLHAPDEGEITVGGVPFASGGGGSRASAGAARRHSTGIGFIHQERLLPATFTVAEALFFPHPPTLGGRASRLARLLPLDVKRMRRDCRAVLHTQFGLDLAPDRLIGELSVAEQQIVQITRALLGRHEILVFDEPSAALVSSEVDRLLRTIERLRANGHTILYVSHYLDEIARVCDRVSVLRDGADVAHFEARAVSRDTLVAAMIGAPQPAATAPSAATARADARVSARADAWGDDAHRAPAGADPARPGARAAPGAIALEARDLALPGRFGPLSLAVRRGEIVGLTGGLGSGGKDVIRALFGLARGVRGSIAVDGRPARVRRPHDAVAHGIALVPENRAAHGVALTLPVRENVVLADLSSVSRFGLVHGRREADVARALIRRLDIRPARPDLPARFLSGGNQQKVALAKWLGRASTVYLLDEPTVGVDVGAKAQIYRLIDALARAGAAVLLFSSDLTELLDVTDRVYVMARGEIVAQCASAETTTQDVLAWATLARDARPGGGAGAHDAAARTGTPGAAGAASSAAKVAT
>NZ_CP004369.1|WP_004542789.1|3318797_3319808_-|sugar-ABC-transporter-substrate-binding-protein
MLFAVALAIGAAPACASPAAGAAPPGPRAGHAPLSLAGKRIGITAAGTDHYWDLQAYQGAVDEVKRLGGTPIALDAGRNDSRQIAQIQTLIAQQPDAIIEQLGTASVLEPWLRKIRQAGIPLFTIDTASPSSLNVVTSDNFAIGSQLALKLVNDIRGEGNVLVFNGFYGVPVCAIRYDQLKAVLKWYPKVKIIEPELRDVIPNTAQNAYAQISQLLQKYPKGAISAIWAAWDIPQVGATQAVDAAGRREIRTYAVDGSPEAVALVRNPTSSAAAVVAQQPALIGRTAVRNVARYLAGDRSLPAYTFVPSVLVTKDDAGVARPALGQAPAAAGLARR
>NZ_CP004369.1|WP_153260263.1|3319935_3320364_-|sugar-ABC-transporter-substrate-binding-protein
MQPFAKLPSKRAAPPPRRIMRRGGLSYGFSCMPARNFALAERFREDFVSFDAARAAAFSDWPAISRFRFNGASSGLFSIALKFICDCPIPIETTRRRSRVPTDIGVGIDAREAAGPASARAGRVRFPPRIFACAARAFAAIP
>NZ_CP004369.1|WP_004206353.1|3320526_3321219_+|isoprenylcysteine-carboxylmethyltransferase-family-protein
MATTRRHATATALAAAARPCAAPHADSFLGILIEVFARVVAALALGVFAYAAYLQWRLDPSRITLILLAVSTTLTVGLSLFAEPPKKRDWSPLALFFSVGGTFYYLVFQLTASRQLLPEAAGAAIQLIGLFWQLFAKVSLRKSFGILPANRGIVSRGAYRFVRHPMYLGYLIIDAGFLLTNFSARNLIAVALQIGLQLGRIRREERLLSEDAAYRAYRRSVRYRVIPGLF
>NZ_CP004369.1|WP_009976571.1|3321552_3321804_-|hypothetical-protein
MFSTRSHVLPRVVLLGEPLANAPFVDGEITRPFRDGFWLLPHSTLCLPLAASDMVIVEPDWPGSAGALAGRQLDAGRQSPSPL
>NZ_CP004369.1|WP_004524124.1|3321966_3323226_-|monooxygenase
MSHAPADPTRSTGADYASLAARFRPIFARIAEGAIERDRTRALPHEPIRWLKEAGFGALRVPVHAGGAGASVPQLVQLLIELAAADSNLPQALRGHFAFVEDWLNAPPDAARRAWFDRFASGQLVGNAWTEVGDVALGEVRTKVAKRDGGWVVNGEKYYSTGAIFADWIDVYAQRTDDGGPVIAAVAARQDGVILGDDWDGFGQATTGSGTTRFVDAHVDEANVIDFARRFKYQTAFYQLFHLATLAGIGRAVERDASALVRGRRRVYSHGNAPRVSDDAQILQVVGEISAWAYAAEAIALRAAQPSQRAYEARGGGDAAAEHDANVAAEIESAQGQLVVSELVLRAATHLFDALGASATRATNALDRHWRNARTVASHNPLVYKARIVGDRAVNGTEPPYVWQIGAGPGGPREPEQAA
>NZ_CP004369.1|WP_004542817.1|3323445_3324909_-|MFS-transporter
MSTLDLDAPISTPIRTASDVSRLINASGARANHARVIVLLALGGVFLDAYDLTTLSYGIEDVTREFGLTPALSGLVSASIMIGTILGSLLGGWFTDKVGRYRVFMADMLCFVVAAIVAGLAPNVGVLIAARFVMGLGVGIDLPVAMAFLAEFSKFGGRGNKASRLAAWCPMWYAASSVCFLIVFGLYFALPAEHARWLWRASLIFGAVPALAIIAVRGRYMNESPLWAANQGKLRDAARILRESYGIRAHAADDTPRAAPSQPPVSFRVLFRQPYLPRTLVASAMNLCIPFEYTAIAFFLPTILTQFLGAGVFETIAATLALNVLFALTGGLLGMRLAYRLPSRRVAIAGFALQAAALVTLALLGHPRTALGIGAAVLMLGLWLFAEGFGPGAQMMIYPALSYPASIRGTGLGFGRALTGIGSAFALFVLPILNARLGAGMFWIVAIAAFVPIVFLAAIRFEPTARDVDIDAGPRAQGDRARVRAAA
>NZ_CP004369.1|WP_004198472.1|3325383_3325632_-|hypothetical-protein
MKAPIIAIAFGIALAACAPLRQDSRPGEAGPPIAAPNRGGGNTPPSGARRAANEVVDYAGRPCVNQTLYVKTHPCIFPRLQR
>NZ_CP004369.1|WP_004524130.1|3326286_3326559_+|DUF4148-domain-containing-protein
MNTKTTIVWATAAALTALALSPAAFAQGKTRDEVRQELIRAQHEGVVPAGKNDYPPSAALVARNKELHAISVHGGKTDLALDQHDQTVAR
>NZ_CP004369.1|WP_004542826.1|3326662_3328057_-|heavy-metal-sensor-histidine-kinase-IrlS
MIRRLLPRTLRARLTALIILSTAATLALSGVALYSALHNRLVGMSSYEMSATLAAMRTHLANVANVDDIPRKSDLWIDQLHGHQNLDLAIYDTDGRLRFATRGFVAPRPALGAPQTRVPASAAPAGATFSYLADDAPLRGGNPRTARIVVQYDGKNDHALLRAYAYTVVVIEVLAVVLTAALAYGIAMLGLSPLRRLVARAEQMSSSRLAQPLPELDTSGELKEMEHAFNAMLKRLDESFVRLSQFSSNLAHDMRTPLTNLLAEAQVALSKPRTADEYRDVIESSIDEYQRLSRMIEDMLFLARSDNAQSHLAIRTLDAAAQAERVAGYYEPMAEDAEVSIVVRGKAEVRADALLYHRALSNLISNALNHAPRGSTITIECAQAADAATISVSDTGRGIEAPHRERIFERFYRVDPARHNSASGTGLGLAIVRSIMENHGGTCGVDSEPHVRTTFWLRFPAHAA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

963004 : 1044071

Leptospira_phage(22.22%)

transposase,protease,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004540193.1\|963004_963982_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_024430891.1\|964124_965369_-	hypothetical protein	NA	NA	NA	NA
WP_158332262.1\|965361_965808_+\|transposase	transposase	NA	NA	NA	NA
WP_085966798.1\|967648_968748_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	9.1e-37	37.3
WP_144084137.1\|971878_972283_-	hypothetical protein	NA	NA	NA	NA
WP_071898245.1\|972230_972740_-	AAA family ATPase	NA	NA	NA	NA
WP_004540177.1\|974462_975722_-	DUF3443 family protein	NA	NA	NA	NA
WP_020850102.1\|975718_976198_-	DUF2844 domain-containing protein	NA	NA	NA	NA
WP_124518502.1\|978417_978519_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_004540565.1\|978549_978768_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_004540443.1\|979215_979929_-	response regulator transcription factor	NA	NA	NA	NA
WP_071898247.1\|982120_982621_-	hypothetical protein	NA	NA	NA	NA
WP_004540369.1\|983738_985160_-	Do family serine endopeptidase	A0A1B1IT49	uncultured_Mediterranean_phage	1.5e-20	28.5
WP_004540191.1\|985499_986342_-	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_004540242.1\|986412_987192_-	SapC family protein	NA	NA	NA	NA
WP_124518497.1\|987201_989532_-	hypothetical protein	NA	NA	NA	NA
WP_020849944.1\|989656_1005952_-	putative bpaA	NA	NA	NA	NA
WP_043944145.1\|1006241_1006598_-	H-NS histone family protein	NA	NA	NA	NA
WP_085966799.1\|1008065_1009164_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.3e-55	43.0
WP_080002865.1\|1009297_1009909_-	MepB family protein	NA	NA	NA	NA
WP_020850359.1\|1013634_1015107_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_004190933.1\|1016539_1018582_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	4.2e-35	32.0
WP_004540553.1\|1018640_1018979_+	hypothetical protein	NA	NA	NA	NA
WP_004190679.1\|1019025_1020900_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.9e-67	36.2
WP_004190948.1\|1020994_1021441_-	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	8.8e-23	48.6
WP_004190342.1\|1021607_1021820_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_004540586.1\|1021899_1023123_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011204325.1\|1023268_1024309_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.7e-93	53.1
WP_004195713.1\|1024705_1025515_-	GTP cyclohydrolase I FolE2	NA	NA	NA	NA
WP_004540286.1\|1025665_1027570_-	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_004525142.1\|1027653_1028538_-	(2E,6E)-farnesyl diphosphate synthase	NA	NA	NA	NA
WP_004190549.1\|1028534_1028828_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_004190814.1\|1029097_1030204_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004190656.1\|1030351_1031221_+	sulfurtransferase	NA	NA	NA	NA
WP_004190499.1\|1031279_1032155_-	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_004539387.1\|1032314_1032536_-	hypothetical protein	NA	NA	NA	NA
WP_004529029.1\|1032718_1034668_+	membrane protein	NA	NA	NA	NA
WP_004190401.1\|1034889_1036272_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_004540200.1\|1036590_1039362_-	DNA polymerase I	S5M8J1	Bacillus_phage	6.4e-71	30.0
WP_004530319.1\|1039363_1040113_+	TIGR00730 family Rossman fold protein	A0A1D8KUT5	Synechococcus_phage	5.6e-22	37.8
WP_004190924.1\|1040109_1040379_+	hypothetical protein	NA	NA	NA	NA
WP_004529031.1\|1040530_1040815_+	hypothetical protein	NA	NA	NA	NA
WP_004540549.1\|1041474_1041966_+	DUF523 domain-containing protein	NA	NA	NA	NA
WP_004540321.1\|1042402_1042666_-	hypothetical protein	NA	NA	NA	NA
WP_004540326.1\|1042844_1044071_-\|protease	trypsin-like serine protease	NA	NA	NA	NA

DBSCAN-SWA_2

1416602 : 1487909

Planktothrix_phage(15.38%)

transposase,plate,integrase

attL 1411230:1411249|attR 1491508:1491527

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1411230:1411249	attL	NA	NA	NA	NA
WP_004540471.1\|1416602_1418288_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_020850088.1\|1418737_1423306_-	RHS repeat-associated core domain protein	A0A2H4JFP5	uncultured_Caudovirales_phage	2.4e-22	34.3
WP_004524859.1\|1423319_1424588_-	hypothetical protein	NA	NA	NA	NA
WP_009935223.1\|1426523_1426970_-	hypothetical protein	NA	NA	NA	NA
WP_153260275.1\|1426948_1427539_-	hypothetical protein	NA	NA	NA	NA
WP_004540568.1\|1428123_1428723_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_004524853.1\|1428747_1429158_-	RidA family protein	NA	NA	NA	NA
WP_004524852.1\|1429272_1430382_-	asparaginase	NA	NA	NA	NA
WP_004557904.1\|1430562_1431195_+	DNA-binding protein	NA	NA	NA	NA
WP_004524850.1\|1432096_1432534_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_020849981.1\|1433770_1434844_-	porin	NA	NA	NA	NA
WP_004540527.1\|1435261_1436686_-	aldehyde dehydrogenase (NADP(+))	NA	NA	NA	NA
WP_011205727.1\|1436901_1438086_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_020850047.1\|1438096_1438984_-	aldose 1-epimerase	NA	NA	NA	NA
WP_004524844.1\|1438986_1439757_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_020850130.1\|1439771_1440635_-	sugar ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-13	25.4
WP_004524842.1\|1440631_1441600_-	ABC transporter permease	NA	NA	NA	NA
WP_004540209.1\|1441620_1442619_-	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004524840.1\|1442656_1443859_-	mandelate racemase/muconate lactonizing enzyme family protein	Q6A202	Oenococcus_phage	6.9e-46	31.9
WP_004557914.1\|1443869_1444583_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_004540362.1\|1444714_1445605_+	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_004540151.1\|1446045_1446642_-	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	6.0e-27	38.1
WP_004540399.1\|1450134_1450482_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.1e-40	72.9
WP_004552577.1\|1450478_1450886_-\|transposase	transposase	A0A0P0ZCV4	Stx2-converting_phage	2.9e-12	37.3
WP_038733539.1\|1451318_1453352_-	hypothetical protein	NA	NA	NA	NA
WP_038733536.1\|1453592_1455764_-	alpha-galactosidase	NA	NA	NA	NA
WP_004524829.1\|1455768_1456620_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_004524828.1\|1456620_1457544_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_004540455.1\|1457605_1458847_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_020849913.1\|1458882_1460127_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	7.1e-22	32.8
WP_041188417.1\|1460169_1460808_-	hypothetical protein	NA	NA	NA	NA
WP_004536893.1\|1462580_1463735_-	LacI family transcriptional regulator	NA	NA	NA	NA
WP_004524822.1\|1465078_1465819_+	hypothetical protein	NA	NA	NA	NA
WP_024429920.1\|1466247_1466403_+	recombinase family protein	A0A286S1P7	Klebsiella_phage	1.8e-07	75.7
WP_020850165.1\|1466368_1466875_+	recombinase family protein	A0JC18	Ralstonia_phage	2.2e-17	51.7
WP_076847933.1\|1469161_1469728_-	suppressor of fused domain protein	NA	NA	NA	NA
WP_085966800.1\|1472865_1474046_-\|transposase	IS3-like element ISBps1 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.2e-60	42.9
WP_004540288.1\|1474672_1475824_+	hypothetical protein	NA	NA	NA	NA
WP_071811398.1\|1475834_1476122_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004540427.1\|1477129_1479061_-\|transposase	transposase	S5WIU1	Leptospira_phage	6.9e-32	50.4
WP_041188419.1\|1478990_1479701_-	hypothetical protein	NA	NA	NA	NA
WP_004203275.1\|1479716_1481921_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_004540478.1\|1481917_1484584_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	1.8e-78	30.7
WP_004540225.1\|1484562_1486041_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004524812.1\|1486037_1487909_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
1491508:1491527	attR	NA	NA	NA	NA

DBSCAN-SWA_3

2385183 : 2394509

Burkholderia_virus(57.14%)

transposase,integrase

attL 2380113:2380129|attR 2406316:2406332

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2380113:2380129	attL	NA	NA	NA	NA
WP_004188376.1\|2385183_2387166_+	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.8e-83	44.8
WP_004547951.1\|2387263_2387644_+	DUF4212 domain-containing protein	NA	NA	NA	NA
WP_004525415.1\|2387637_2389653_+	cation acetate symporter	NA	NA	NA	NA
WP_004542585.1\|2389948_2391148_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A4JX31	Burkholderia_virus	1.1e-224	99.5
WP_004542626.1\|2391144_2391294_-	bacteriophage protein Gp44	Q8W6Q6	Burkholderia_virus	7.4e-19	98.0
WP_004542548.1\|2391549_2392131_+	hypothetical protein	A9YX38	Burkholderia_phage	2.2e-21	100.0
WP_004552392.1\|2392361_2392580_-	hypothetical protein	Q6JIH9	Burkholderia_virus	9.8e-36	98.6
WP_004525418.1\|2392627_2392849_-	hypothetical protein	NA	NA	NA	NA
WP_004552388.1\|2393125_2393401_-	bacteriophage protein Gp49	Q6JIH4	Burkholderia_virus	2.3e-42	96.7
WP_009923450.1\|2393971_2394241_+	BrnT family toxin	NA	NA	NA	NA
WP_004525420.1\|2394224_2394509_+	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	1.4e-10	50.0
2406316:2406332	attR	NA	NA	NA	NA

DBSCAN-SWA_4

2547193 : 2618698

Vibrio_phage(25.0%)

plate,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004525541.1\|2547193_2547961_-\|holin	phosphocholine cytidylyltransferase family protein	NA	NA	NA	NA
WP_004542630.1\|2547999_2549001_-	HpnL family protein	NA	NA	NA	NA
WP_004542606.1\|2548997_2549771_-	hypothetical protein	NA	NA	NA	NA
WP_004188272.1\|2549767_2550457_-	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_004188420.1\|2550822_2552337_+	acetyl-CoA hydrolase/transferase family protein	NA	NA	NA	NA
WP_004525545.1\|2554046_2554985_+	hypothetical protein	NA	NA	NA	NA
WP_004202234.1\|2555018_2555567_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190846.1\|2555569_2557075_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004530039.1\|2557218_2557746_+	hypothetical protein	NA	NA	NA	NA
WP_004190879.1\|2557825_2558257_+	GPW/gp25 family protein	NA	NA	NA	NA
WP_004196180.1\|2558270_2560133_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004190851.1\|2560129_2561119_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004525547.1\|2561121_2563992_+	type VI secretion system ATPase TssH	A0A2I7REQ1	Vibrio_phage	2.4e-60	27.2
WP_004525548.1\|2563982_2566274_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004190563.1\|2566439_2568728_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004542632.1\|2568731_2570948_+	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_004525550.1\|2570947_2572018_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004530790.1\|2572020_2572737_+	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004190606.1\|2572779_2573169_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004202226.1\|2573174_2573768_+	hypothetical protein	NA	NA	NA	NA
WP_020850152.1\|2573764_2575126_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004525553.1\|2575208_2576867_+	OmpA family protein	NA	NA	NA	NA
WP_004525554.1\|2576863_2580367_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004190863.1\|2580425_2580785_+	hypothetical protein	NA	NA	NA	NA
WP_004190471.1\|2580807_2581233_+	hypothetical protein	NA	NA	NA	NA
WP_004536812.1\|2581553_2581829_+	hypothetical protein	NA	NA	NA	NA
WP_004524288.1\|2582379_2583279_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004542286.1\|2583320_2583611_-	hypothetical protein	NA	NA	NA	NA
WP_020850331.1\|2583500_2584820_+	glycosyltransferase	NA	NA	NA	NA
WP_004528658.1\|2584816_2586403_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004524284.1\|2586691_2587687_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_004528656.1\|2587982_2589566_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004186853.1\|2590058_2591312_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004543122.1\|2591844_2593509_-	glycoside hydrolase family 32 protein	F8WPR5	Bacillus_phage	9.2e-57	31.6
WP_004186967.1\|2593641_2595126_-	glycoside hydrolase 68 family protein	NA	NA	NA	NA
WP_004530800.1\|2595395_2596412_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_004523135.1\|2596851_2598051_+	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	8.4e-12	27.2
WP_004198247.1\|2598228_2599254_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004543129.1\|2599688_2600963_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	9.0e-105	54.1
WP_004186989.1\|2601035_2602007_+	membrane dipeptidase	NA	NA	NA	NA
WP_004186987.1\|2602157_2602691_+	4-vinyl reductase	NA	NA	NA	NA
WP_004523137.1\|2602751_2604815_+	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_004186901.1\|2604817_2606743_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_004202150.1\|2606747_2607920_+	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_004530055.1\|2607916_2608702_+	drug:proton antiporter	NA	NA	NA	NA
WP_009975601.1\|2608753_2609995_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004543120.1\|2610015_2611161_+	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004186918.1\|2611270_2612134_+	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004530057.1\|2612314_2613970_+	APC family permease	NA	NA	NA	NA
WP_004186920.1\|2614056_2614932_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_021252052.1\|2615075_2615948_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004543140.1\|2616110_2617664_+\|holin	choline-sulfatase	NA	NA	NA	NA
WP_041188444.1\|2617660_2618698_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA

DBSCAN-SWA_5

3354302 : 3361063

Burkholderia_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006027262.1\|3354302_3354599_+	type II toxin-antitoxin system RelE/ParE family toxin	A4JWV2	Burkholderia_virus	5.6e-50	99.0
WP_004202809.1\|3354601_3354958_+	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.9e-42	100.0
WP_004542845.1\|3355001_3355151_-	hypothetical protein	A4JWV0	Burkholderia_virus	9.1e-09	96.3
WP_020850286.1\|3356147_3356630_-	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_041188525.1\|3356699_3357599_-	hypothetical protein	A0JC16	Ralstonia_phage	6.3e-36	39.1
WP_020850011.1\|3358100_3358685_-	hypothetical protein	A0A0K2QQ53	Ralstonia_phage	2.5e-09	53.1
WP_020850148.1\|3358784_3360161_-	type II/III secretion system protein	NA	NA	NA	NA
WP_020850003.1\|3360157_3361063_-	AAA family ATPase	Q6UAZ2	Ralstonia_phage	1.1e-27	37.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP004368

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP004368_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004368_1

252554-252633

Orphan

Consensus_repeat	Method
ACGGAATGGGCCCCGGCATGATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP004368_1

>merge|NZ_CP004368|1|252554-252633|CRISPRCasFinder
ACGGAATGGGCCCCGGCATGATGGGCGGCGGCTACGGGCGCGGAATGACGGGCGGCTACGGAATGGGGCCCGGCATGATG

>NZ_CP004368|1|1|252554-252633|CRISPRCasFinder
ACGGAATGGGCCCCGGCATGATG	GGCGGCGGCTACGGGCGCGGAATGACGGGCGGCT
ACGGAATGGGGCCCGGCATGATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004368.1\|WP_004523107.1\|245638_245923_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004368.1\|WP_004543087.1\|251349_252318_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP004368.1\|WP_004197761.1\|260070_260487_+\|lactoylglutathione-lyase	unknown	unknown	gnl\|CDD\|319916
NZ_CP004368.1\|WP_004524601.1\|263473_263629_-\|lipoprotein	unknown	unknown	gnl\|CDD\|215083
NZ_CP004368.1\|WP_020850573.1\|258574_259669_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	unknown	unknown	gnl\|CDD\|185333
NZ_CP004368.1\|WP_004201742.1\|250112_251207_-\|polyamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270377
NZ_CP004368.1\|WP_004523118.1\|255864_257478_-\|glutamate--cysteine-ligase	unknown	unknown	gnl\|CDD\|235001
NZ_CP004368.1\|WP_004543103.1\|254397_255846_+\|RNA-polymerase-sigma-factor-RpoD/SigA	unknown	unknown	gnl\|CDD\|274108
NZ_CP004368.1\|WP_004525837.1\|253586_254135_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004368.1\|WP_004543093.1\|248971_250084_-\|class-II-histone-deacetylase	unknown	unknown	gnl\|CDD\|212521
NZ_CP004368.1\|WP_004200731.1\|245159_245642_+\|DUF2778-domain-containing-protein	unknown	unknown	gnl\|CDD\|378506
NZ_CP004368.1\|WP_004524603.1\|262237_262798_-\|spermidine-N1-acetyltransferase	unknown	unknown	gnl\|CDD\|237916
NZ_CP004368.1\|WP_161807729.1\|247419_247791_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004368.1\|WP_004536432.1\|261404_261752_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004368.1\|WP_004543109.1\|257636_258578_-\|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl\|CDD\|223200
NZ_CP004368.1\|WP_004200732.1\|242340_242745_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NZ_CP004368.1\|WP_004543096.1\|243618_244623_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369676
NZ_CP004368.1\|WP_004189258.1\|248085_248961_-\|N-carbamoylputrescine-amidase	unknown	unknown	gnl\|CDD\|274553
NZ_CP004368.1\|WP_004197759.1\|260634_261189_-\|YaeQ-family-protein	unknown	unknown	gnl\|CDD\|377782
NZ_CP004368.1\|WP_004543108.1\|245995_247087_-\|phage-portal-protein	unknown	unknown	gnl\|CDD\|222860

Protein	Function_ID	Function_description	E-value
NZ_CP004368.1\|WP_004543087.1\|251349_252318_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.91549e-71
NZ_CP004368.1\|WP_004197761.1\|260070_260487_+\|lactoylglutathione-lyase	gnl\|CDD\|319916	cd07253, GLOD5, Human glyoxalase domain-containing protein 5 and similar proteins. Uncharacterized subfamily of VOC family contains human glyoxalase domain-containing protein 5 and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.46868e-30
NZ_CP004368.1\|WP_004524601.1\|263473_263629_-\|lipoprotein	gnl\|CDD\|215083	PLN00162, PLN00162, transport protein sec23; Provisional.	0.00226922
NZ_CP004368.1\|WP_020850573.1\|258574_259669_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	gnl\|CDD\|185333	PRK15435, PRK15435, bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada.	2.13126e-121
NZ_CP004368.1\|WP_004201742.1\|250112_251207_-\|polyamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	7.3532e-149
NZ_CP004368.1\|WP_004523118.1\|255864_257478_-\|glutamate--cysteine-ligase	gnl\|CDD\|235001	PRK02107, PRK02107, glutamate--cysteine ligase; Provisional.	0
NZ_CP004368.1\|WP_004543093.1\|248971_250084_-\|class-II-histone-deacetylase	gnl\|CDD\|212521	cd09996, HDAC_classII_1, Histone deacetylases and histone-like deacetylases, classII. This subfamily includes bacterial as well as eukaryotic Class II histone deacetylase (HDAC) and related proteins. Deacetylases of class II are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. Included in this family is a bacterial HDAC-like amidohydrolase (Bordetella/Alcaligenes species FB18817, denoted as FB188 HDAH) shown to be most similar in sequence and function to class II HDAC6 domain 3 or b (HDAC6b). FB188 HDAH is able to remove the acetyl moiety from acetylated histones, and can be inhibited by common HDAC inhibitors such as SAHA (suberoylanilide hydroxamic acid) as well as class II-specific but not class I specific inhibitors.	1.14721e-173
NZ_CP004368.1\|WP_004200731.1\|245159_245642_+\|DUF2778-domain-containing-protein	gnl\|CDD\|378506	pfam10908, DUF2778, Protein of unknown function (DUF2778). This is a bacterial family of uncharacterized proteins.	2.57059e-50
NZ_CP004368.1\|WP_004524603.1\|262237_262798_-\|spermidine-N1-acetyltransferase	gnl\|CDD\|237916	PRK15130, PRK15130, spermidine N1-acetyltransferase; Provisional.	7.47948e-86
NZ_CP004368.1\|WP_004543109.1\|257636_258578_-\|DNA-3-methyladenine-glycosylase-2-family-protein	gnl\|CDD\|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	5.53327e-54
NZ_CP004368.1\|WP_004200732.1\|242340_242745_-\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	4.3525e-28
NZ_CP004368.1\|WP_004543096.1\|243618_244623_+\|hypothetical-protein	gnl\|CDD\|369676	pfam08065, K167R, K167R (NUC007) repeat. This family represents the K167/Chmadrin repeat. The function of this repeat is unknown.	0.00506459
NZ_CP004368.1\|WP_004543103.1\|254397_255846_+\|RNA-polymerase-sigma-factor-RpoD/SigA	gnl\|CDD\|274108	TIGR02393, RNA_polymerase_sigma_factor_RpoD, RNA polymerase sigma factor RpoD, C-terminal domain. This model represents the well-conserved C-terminal region of the major, essential sigma factor of most bacteria. Members of this clade show considerable variability in domain architecture and molecular weight, as well as in nomenclature: RpoD in E. coli and other Proteobacteria, SigA in Bacillus subtilis and many other Gram-positive bacteria, HrdB in Streptomyces, MysA in Mycobacterium smegmatis, etc. [Transcription, Transcription factors].	2.71742e-88
NZ_CP004368.1\|WP_004197759.1\|260634_261189_-\|YaeQ-family-protein	gnl\|CDD\|377782	pfam07152, YaeQ, YaeQ protein. This family consists of several hypothetical bacterial proteins of around 180 residues in length which are often known as YaeQ. YaeQ is homologous to RfaH, a specialized transcription elongation protein. YaeQ is known to compensate for loss of RfaH function.	3.23549e-104
NZ_CP004368.1\|WP_004543108.1\|245995_247087_-\|phage-portal-protein	gnl\|CDD\|222860	PHA02536, Q, portal vertex protein; Provisional.	0
NZ_CP004368.1\|WP_004189258.1\|248085_248961_-\|N-carbamoylputrescine-amidase	gnl\|CDD\|274553	TIGR03381, putative_carbon-nitrogen_hydrolase, N-carbamoylputrescine amidase. Members of this family are N-carbamoylputrescine amidase (3.5.1.53). Bacterial genes are designated AguB. The AguAB pathway replaces SpeB for conversion of agmatine to putrescine in two steps rather than one. [Central intermediary metabolism, Polyamine biosynthesis].	0

>NZ_CP004368.1|WP_004543087.1|251349_252318_+|LysR-family-transcriptional-regulator
MRRIDLLSALETFVCAVEEGSLSQAARRLAKTPSAVTKAIAGLEATLGVQLLERTTRRLALTESGRLYLATATDVLRRLADGARQLSERDDEPRGLLRVTAAHSFGHAILAPLCAPFAQAFPRVRIELSLSDHYVDIVGEGFDLALRMGNYDLPSQIVKPIGSNRGLLCASPGYLARRGRPTAPADLAQHDCVIYRHPTLANTWTFERGGVRARLEPKGPLVTDDYGLALAAALDGAGVLPCPQWSVVDALEAGRLVPLLVDWRFESASFGEDRICAAYPSSRRGSTKIRRLVERVQARLADSEARVARVLGDALCADLARR
>NZ_CP004368.1|WP_004201742.1|250112_251207_-|polyamine-ABC-transporter-substrate-binding-protein
MKRIAWLAAVLASLACAAARAADGNVLNIYNWAEYFAPDTIADFEKETGIKVRLDVYDSNEALQTKLTTGNSGYDLVFPSNDFLARQIQAGLYRKLDKSRLPNLTNLDPAIVARAAEVDPGNQYSVPYMQGTFGLGLNIAKVKQALGGPLPANTLELIFNPAYAAKLERCGIAFNDAGSEVFPLALRYIGRDPNTTDPRDYEAALDMMKKIRPTIRQFIATPVMNDLATGDVCVVTGYSGAVLVAARRAAEAKNGQQIVYSLPSAGAPFWFDSMAIPKGAAHADHALRFIDYILRPDVVAKISNKVMYPNPNRVATPLVDRRLTANPAIYPDAATMRTLWVKRPMPPQAMRMQTRYWTRFKTGY
>NZ_CP004368.1|WP_004543093.1|248971_250084_-|class-II-histone-deacetylase
MIPTGLLFDPAFLSHRQGDLVYVVPHGTLNLGEHFDSPLRLAYTKQLLDAVGMTERLTRVAFARATDEQLLRVHRPEYLRQLAEACAVAGEQVVRLGDDAAGSASTEDVARLAAGAACAAVDAVMTGPLRQAYALIRPSGHHAGADFAMGYCYYNNVAIAARHAQAAHGVERVAIVDWDVHHGNGTQQAFYDDPSVLFVSLHEAANFPVDGGEARETGGGAGAGYNVNVPLPSGTGDAGYRHAFDELVLPLVEAFAPQLILVSAGQDANAFDPLGRMRVQRDGFRHMARALRQAAGGACGGRIVMLQEGGYSLPYLPIATLGVLEGLVGWNAPFDDPHQFVQYPLGEGERAAVKAARAALAPYWPTLHRS
>NZ_CP004368.1|WP_004189258.1|248085_248961_-|N-carbamoylputrescine-amidase
MRKTTVAVTQMACDWNVDANLSRAERLVRDAAARGAQIVLLQELFETPYFCIDQHPAHLALAQPYEGHPWLMRFASLARELGVVLPVSFFERAGQTQFNSVAIFDADGRALGIYRKTHIPDGPGYTEKYYFTPGDTGFRVWDTAYGRIGVGICWDQWFPECARAMALAGAELLLYPSAIGSEPHDASIDSRAHWRNAQRGHAAANLMPVAASNRVGVERGASGEIVFYGSSFIAGADGEMIVECDRHGEAIATAEFDLDALAYRRRGWGVFRDRRPECYRALSEGAADRVR
>NZ_CP004368.1|WP_161807729.1|247419_247791_-|hypothetical-protein
MPPSVRPPRGRHVRAIGAGRRGNASGRFATTFCWGAQARGRAVADRGVAFDCEDAEAAAQLLEHAIALEEVDLMREDAILGDGKPDVVRAAEITFLYRAELHRGGSPRAVGLGMLYFRGSSDH
>NZ_CP004368.1|WP_004543108.1|245995_247087_-|phage-portal-protein
MSSWRRRASTTAPSACSNVTSSAATTLRNRPRQIRAPARAEVFTFDDPTPVMNRAEILDYVECWSNGEWFEPPVSFAGLAKSFRASTHHSSALFFKANVLASTFRPHRWLSRHAFERWALDFLTFGNGYLERRRNMVGGTLRLEPALAKYVRRKADFSGFVYVNGWQDRHEFAPDSVFQLVRPDINQEVYGLPEYLSSLHSAWLNESSTLFRRKYYENGSHAGFILYMIDAAQKQDDVDNMRDALKNAKGPGNFRNVFMYAPGGKKDGIQLIPVSEVAAKDEFFNIKNVTRDDLLAAHRVPPQLLGIVPSNSGGFGTPDTAARVFGRNEIRPLQARFAELNDWLGEEVVTFDDYEIPPAPVAA
>NZ_CP004368.1|WP_004523107.1|245638_245923_+|hypothetical-protein
MKTIGRILLALVLTWPLLTGISSLPLLTHWFANGGEGWNALSPVFRALGSDGGEQNEEIFVGILLVISFVLALVLSFALFGLVDRLRHSTDRRA
>NZ_CP004368.1|WP_004200731.1|245159_245642_+|DUF2778-domain-containing-protein
MPAECTFVLNRSRLSTLTCPGFGSVPAFSGNGRYINDPGSTAVADKGPLPAGVYYIIDRQSGGHLGWFRDTVMDAALNTYRAEWFALYRIDGQIDDWTIVNGIRRGHFRLHPVGRLGESDGCITLTSRGQFDKLRAFLKAQPTTQVPGTSFRAYGKVTVK
>NZ_CP004368.1|WP_004543096.1|243618_244623_+|hypothetical-protein
MAQKKKVVYFLGAGASFGAGAKATVQAGHQLPIPTQATFWPTFLRFCKSQKNCARIESFLFRYFLGYGKTPVRTPAAKRRHLLTSIDVEEVFTFLSERTRAPSTSTQLRTYALQVWGALAEEIGQVFSRFNANSATKAIYKDFLKHHFRRFDTVVSFNYDTIFENSLPARRSARYVGLRDSAGTIPLLKPHGSVNWVQADDGTITVGNPVGPAVIVAPTHLKFISDPDQKEVQHPGYLDQAHEIQKIWAEMEREMRFARSLVFIGYSFPVADLYFASVLRSVLADRDTTPNIVIVNPDAVAISERLLRRFPLVTVSRFFDLAQFIRAGRAVIAQ
>NZ_CP004368.1|WP_004200732.1|242340_242745_-|PaaI-family-thioesterase
MDENTVRDLLDRLLAPWVRSLSLTPVSISEESVTLRLPFSGEFRHSGGVICGQVFMAAADTAMVVAISAALGEFRPMTTVALNTHFMRPVRKGDVLVTARVLRMGRNLVFGEIELFDEDGKMAVHATSTYALVS
>NZ_CP004368.1|WP_004525837.1|253586_254135_+|hypothetical-protein
MEEAYARRALLLHLGSVLQILSRLEGAPDNQSIEALLAANGMLADVPLVEYVVQDMTVREFSARALRAFCLWPQLLLEDPLDCAALALPVRKHLFAGNDAGWKAYAATLREVSPGFDTARSYAAEPHEAEFDLADERDAETGDGPVERDDEADDDGRLRERAAASVESATPAGAPVRRESYE
>NZ_CP004368.1|WP_004543103.1|254397_255846_+|RNA-polymerase-sigma-factor-RpoD/SigA
MKVSARELRYEQGIDRLLELAGARDDTEYADVADEFASAPSSAFAHDLGEPDSLDHQASDESAGAGSFGDKPTRPAHGDTDVDTDWRDDDAPPSGSNDAAPVDTAASTDPLALFVRRMHAVPLLTHAQEIALAAEIEAGREQVLQALAEALDRLDLASLPADPALGRARAALQRARARGDEGARAFARARTAAYAALAAHGWPSAEVDAVRRAMRRLPTSPEKSDAGAQRAFADGEARISAATARMAEANLRLVLSIARKYASRGLDLADLLQEGNLGLLRAIEKFEHRRGFKFSTYATWWIRQAISRAIADRARTIRVPVHVGDEARRVRKAADRIERRSGVSASLAELSEATGLPAERLRAVLTLPREPRSLNAPLGDDDQAEFGDIVEDTSTPSLFDALAHGQMCDVVTSLLKTMSAQEADILRRRFGIGGDEPWSYEQIAARAGVSREQVRRIEKRALQTLRVTAEACNAHDFLDVQP
>NZ_CP004368.1|WP_004523118.1|255864_257478_-|glutamate--cysteine-ligase
MPNNMTSRQTDLLQQRLAVLSTSPTREQLPDGLRGIEKESLRVTRDGMIAFTPHPRALGSALTHPSLTTDYSEALVELITPAERDAATTLERLDELHRYVYASLGDEMLWTDSMPGLLPADDEIPIADYGTSNIGRLKTVYRRGLAYRYGRTMQCIAGIHYNYSLSEEVWRRLHAEEGSTASIVDYQSERYLALIRNFRRTSWLLMYLFGASPALDAGFLRGRAHKLDTFDAATLYRPHATSLRMSDLGYSNTTAQAALQADYNTLSGYLDALSKAVSEPYPPYEAIGTHRDGEWIQINTNVLQIENEFYSTIRPKRVTYSGERPLHALASRGVQYIEVRCLDIDPFEPTGIALDTARFLDAYLLVCALDESAPLTCDAYRESNANFGRVTMEGRKPGLELTRDGAAVPMRAWADEIFAQIEAAGRVLDDIRGDDAHARAIAAQRAKLDDPELTSSARVLRAMRENGQSFLEFARAQSAAHAAYFHGRPLDEAATRDARALAERSLAEQAELEGKNAGSFDAFVAAYRAYTLNRFSV
>NZ_CP004368.1|WP_004543109.1|257636_258578_-|DNA-3-methyladenine-glycosylase-2-family-protein
MSAAVEPAAVRPDSVVLELPFKSPYDWPRVLRFFAGRAIPGVEAVGDGAYRRTVDHHGAIGTLTVRKHPRKRCLVALVEGDAARHADAAFAARLSTMFDLQADLAAIGAHLARDAWFAPLVGAAPGLRVPGAWSGFELIVRAIVGQQVSVKAATTIVGRLVERAGERLAPHAPGAIGWRFPEPAALAACDLSRIGMPGKRAAALQGVARAVAAGDVPLDAYASDPAGVRAALLALPGIGPWTVEYVAMRAWRDADAWPATDLVLMQAIVARDPALDRPASQRLRADAWRPWRAYAAMHLWNEIADRAGSARGG
>NZ_CP004368.1|WP_020850573.1|258574_259669_-|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada
MKQPPYPTDDARWAALVARDVDADGAFCYAVKTTGVFCRPSCASRLPRRENVSFFVDTGAARAAGYRPCKRCRPEGLPRELDIVNRACAVLDAHRQDRFTLAQLSDAVHVSPFHLQRLFKRVVGVSPRQYQAAQRGAALRDALQSGAAVTRAAVDAGFNSPSRLYESVPRELGMSPSAFRRKGAGLKIDYATADTRLGVVLVAATSKGICKIAFGDAAAPLVDELRTGFANAQIAESPERIAPFIAQVDAYLNGTRRRFELPLDLAATEFQQRVWDALRRIPYGETRSYTQIAEALGAPRAVRAVASACASNPVALAIPCHRVVQKGGSLAGYRWGLPRKAALLDAEAQRAAGESVESAVDHAA
>NZ_CP004368.1|WP_004197761.1|260070_260487_+|lactoylglutathione-lyase
MKFHIHEIDHVVLRAADLAAMTRFYCDVLGCHVEKEQRELGLVQLRAGRSLIDLLAVGAPIDRAGSGAPGKGRNMDHLCLRVEPFDAAALRTHLAAHGARPGDEARRYGADGYGPSLYLFDPEGNMVELKGPPEAVAP
>NZ_CP004368.1|WP_004197759.1|260634_261189_-|YaeQ-family-protein
MALKSTIYKAELQIADMDRHYYADHSLTVARHPSETDERMMVRIAAFALFAHERLEFCKGLSDTDEPDLWQKDLTGAIEVWIDVGQPDERRIAKASGRAGRVNVIAYGGRTSDIWWQGARGKVERLRNVQVTTLADGVAAALGGLAERTMRLQCTIQDGAAWLSSATHDPVAIEWTTLKAREDA
>NZ_CP004368.1|WP_004536432.1|261404_261752_-|hypothetical-protein
MLKRTGLFLALAGGIVAFSVAQANGDASLKPQQEIQLTKNAWGCLSKDNLDSVLNHERDGKAQAKQQYFDDYRCLSVPEGQRFRVVSVDKGDVQFVSAENSDQQGLWTDARFIKQ
>NZ_CP004368.1|WP_004524603.1|262237_262798_-|spermidine-N1-acetyltransferase
MQIQNEQHTLALRPLERQDLRFVHELNNDAKIMRYWFEEPYETFTELSQLYDQHVHDQRERRFVAFDSDGELVGLVELIELDYIHRRGEFQIIIAPNRQGRGFATRATRLAVEYAFKVLNLRKLYLIVDKSNVAAIRVYEKCGFKHEAELIEEFFGNGQYHNALRMCIFQRDYFAAQPGAELHARE
>NZ_CP004368.1|WP_004524601.1|263473_263629_-|lipoprotein
MKKIIIALAVSAGILSGCAVYVPDQPGVIMAPQGGPGNGFCPPGQAKKGNC

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Crispr_ID: NZ_CP004368_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004368_2

3027127-3027268

Orphan

Consensus_repeat	Method
CGCCGGCGTTCGCCGCATACGCGGCAGACGCCGTTCCTGCGCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP004368_2

>merge|NZ_CP004368|2|3027127-3027268|CRISPRCasFinder
CGCCGGCGTTCGCCGCATACGCGGCAGACGCCGTTCCTGCGCGAGCCGCTGCGAACTTGCGAACGGCATTTCGTCCGCCACCGCTTCAACGCTTGGCACGCCGGCGTTCGCCGCATACGCGGCAGACGCCGTTCCAGCGCGA

>NZ_CP004368|2|2|3027127-3027268|CRISPRCasFinder
CGCCGGCGTTCGCCGCATACGCGGCAGACGCCGTTCCTGCGCGA	GCCGCTGCGAACTTGCGAACGGCATTTCGTCCGCCACCGCTTCAACGCTTGGCA
CGCCGGCGTTCGCCGCATACGCGGCAGACGCCGTTCCAGCGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004368.1\|WP_004193486.1\|3016049_3017246_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_CP004368.1\|WP_020850643.1\|3019779_3020853_-\|cytochrome-b/b6-domain-containing-protein	unknown	unknown	gnl\|CDD\|226602
NZ_CP004368.1\|WP_004193167.1\|3044591_3044771_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004368.1\|WP_160974052.1\|3018536_3018749_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004368.1\|WP_004192513.1\|3043065_3044430_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182566
NZ_CP004368.1\|WP_162473164.1\|3040089_3040548_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237171
NZ_CP004368.1\|WP_041188564.1\|3027944_3029228_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP004368.1\|WP_004542979.1\|3018972_3019764_-\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239026
NZ_CP004368.1\|WP_004542975.1\|3025452_3025677_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004368.1\|WP_004521870.1\|3036532_3039877_-\|exodeoxyribonuclease-V-subunit-gamma	unknown	unknown	gnl\|CDD\|335690
NZ_CP004368.1\|WP_004534949.1\|3025947_3026880_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP004368.1\|WP_004534567.1\|3040604_3042881_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372320
NZ_CP004368.1\|WP_004543005.1\|3030030_3032727_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|236783
NZ_CP004368.1\|WP_004542991.1\|3017597_3018533_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|183067
NZ_CP004368.1\|WP_004193488.1\|3029629_3030034_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|181730
NZ_CP004368.1\|WP_004543008.1\|3032723_3036536_-\|exodeoxyribonuclease-V-subunit-beta	unknown	unknown	gnl\|CDD\|236784
NZ_CP004368.1\|WP_004193339.1\|3021883_3022189_-\|pentapeptide-MXKDX-repeat-protein	unknown	unknown	gnl\|CDD\|131998
NZ_CP004368.1\|WP_004521865.1\|3022833_3024765_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NZ_CP004368.1\|WP_004193128.1\|3024988_3025201_+\|glycine-zipper-2TM-domain-containing-protein	unknown	unknown	gnl\|CDD\|182532
NZ_CP004368.1\|WP_004192878.1\|3042877_3043069_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP004368.1\|WP_004193486.1\|3016049_3017246_+\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.94618e-60
NZ_CP004368.1\|WP_020850643.1\|3019779_3020853_-\|cytochrome-b/b6-domain-containing-protein	gnl\|CDD\|226602	COG4117, COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion].	3.06869e-55
NZ_CP004368.1\|WP_004192513.1\|3043065_3044430_+\|amino-acid-permease	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0
NZ_CP004368.1\|WP_162473164.1\|3040089_3040548_+\|hypothetical-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0.000933571
NZ_CP004368.1\|WP_041188564.1\|3027944_3029228_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	3.3191e-53
NZ_CP004368.1\|WP_004193488.1\|3029629_3030034_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	3.43394e-65
NZ_CP004368.1\|WP_004193128.1\|3024988_3025201_+\|glycine-zipper-2TM-domain-containing-protein	gnl\|CDD\|182532	PRK10540, PRK10540, osmotically-inducible lipoprotein OsmB.	5.81885e-06
NZ_CP004368.1\|WP_004521870.1\|3036532_3039877_-\|exodeoxyribonuclease-V-subunit-gamma	gnl\|CDD\|335690	pfam04257, Exonuc_V_gamma, Exodeoxyribonuclease V, gamma subunit. The Exodeoxyribonuclease V enzyme is a multi-subunit enzyme comprised of the proteins RecB, RecC (this family) and RecD. This enzyme plays an important role in homologous genetic recombination, repair of double strand DNA breaks resistance to UV irradiation and chemical DNA-damage. The enzyme (EC:3.1.11.5) catalyzes ssDNA or dsDNA-dependent ATP hydrolysis, hydrolysis of ssDNA or dsDNA and unwinding of dsDNA. This family consists of two AAA domains.	0
NZ_CP004368.1\|WP_004534949.1\|3025947_3026880_+\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.49752e-12
NZ_CP004368.1\|WP_004534567.1\|3040604_3042881_+\|hypothetical-protein	gnl\|CDD\|372320	pfam12805, FUSC-like, FUSC-like inner membrane protein yccS. This family has similarities to the fusaric acid resistance protein family. The proteins are lodged in the inner membrane.	5.92051e-82
NZ_CP004368.1\|WP_004543005.1\|3030030_3032727_-\|AAA-family-ATPase	gnl\|CDD\|236783	PRK10875, recD, exodeoxyribonuclease V subunit alpha.	2.03735e-72
NZ_CP004368.1\|WP_004542991.1\|3017597_3018533_-\|EamA-family-transporter	gnl\|CDD\|183067	PRK11272, PRK11272, putative DMT superfamily transporter inner membrane protein; Provisional.	8.41633e-57
NZ_CP004368.1\|WP_004542979.1\|3018972_3019764_-\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239026	cd02108, bact_SO_family_Moco, bacterial subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. This domain is found in a variety of oxidoreductases. Common features of all known members of this family, like sulfite oxidase and nitrite reductase, are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate. The specific function of this subgroup is unknown.	6.54795e-91
NZ_CP004368.1\|WP_004543008.1\|3032723_3036536_-\|exodeoxyribonuclease-V-subunit-beta	gnl\|CDD\|236784	PRK10876, recB, exonuclease V subunit beta; Provisional.	0
NZ_CP004368.1\|WP_004521865.1\|3022833_3024765_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NZ_CP004368.1\|WP_004193339.1\|3021883_3022189_-\|pentapeptide-MXKDX-repeat-protein	gnl\|CDD\|131998	TIGR02953, conserved_hypothetical_protein, pentapeptide MXKDX repeat protein. Members of this protein family are small bacterial proteins, each with an N-terminal signal sequence followed by up to 11 imperfect repeats of a pentapeptide. The pentapeptide repeat usually follows the form Met-Xaa-Lys-Asp-Xaa.	0.000353246

>NZ_CP004368.1|WP_004534949.1|3025947_3026880_+|DMT-family-transporter
MNLKNALLLIVLAALWGASFLFIRVGVAEFGVAPLMALRVGIGALFLVALMLTRYAPRELIALLRQHAWPLFVVGLLNSAAPFCLFAFAELTLSAGVTSVINATTPLWGALVAYLWLKDSLSLPRALGLVIGFAGVLTLVWDQVFSPHGANPASPATAALAAAAALGATLLYGIAANFTKRKLTGVDPLVSATGSMVGATILLLPFALATWPAAPVSAHAWGSVLALGIACTGVAYFIFFHLIAHIGPARAITVTFVIPVFGILWGALFLGERVSFAMLEGCVIVLLGTALATGAIRRIPGVRPQRNEAA
>NZ_CP004368.1|WP_004542975.1|3025452_3025677_+|hypothetical-protein
MNKTLVAAALASVALAGCYYPYGYYPASGYYAVPVQTAPVYVAPAYPAYYYPAPSLSLNFGYWSGGGRGYWRHH
>NZ_CP004368.1|WP_004193128.1|3024988_3025201_+|glycine-zipper-2TM-domain-containing-protein
MKSIRRIGVCAMLIATMASLSACDTMTTRQRNAAIGAGIGGVAGAAIGGNALSTIGGAAAGGLVGSQVGK
>NZ_CP004368.1|WP_004521865.1|3022833_3024765_+|phosphomethylpyrimidine-synthase-ThiC
MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLAGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ
>NZ_CP004368.1|WP_004193339.1|3021883_3022189_-|pentapeptide-MXKDX-repeat-protein
MKRNLIAFACVAGFALAAPFAHAQNDAMSKDGMGMSKDAMSKGAMSGDAMSKDAMSKDAMSKDRMGKRHDHMAKGGMKAGPMSKDAMKEPMSSDKMSPMSN
>NZ_CP004368.1|WP_020850643.1|3019779_3020853_-|cytochrome-b/b6-domain-containing-protein
MSATPTTSASTTAMAGARASGAADAPARAPTGADVDAGATAWADATANATANATTDPTIDATADATTDAMANVTTDAATRVTANPPIHETANVPASTAAAATTEAVADARTGTALDAAHPGATQTMSQTMAQTMTQAGTEAASPAGTDAAASGACITRATRARRPIHPLWVRASHWLNALAAVTMALSGWRIYNASPIYAGFVFPRGATLGGWLGGALQWHFAAMWLLFFNGVFYLTMGVATRRFTRKLLPLSASGVARDLRDALRGRLSHDDLSVYNALQRAAYVAAIADLALLVLSGLVIWKSVQFPLLREWFGGYDRARVVHFWAMAFLVAFFVVHVAMAALVPRSLLAMLRGH
>NZ_CP004368.1|WP_004542979.1|3018972_3019764_-|molybdopterin-dependent-oxidoreductase
MAENDRKKRENDIARIDRASLLIDVRKSLALPSRRLFGKRMLTLGGLAMLTGCTLRDDASADDFLEKVSRANDRVQAWLFGPTRLAPTYAEADITRPFPFNAFYGIDDVPRVDADGFRLAVSGLVTGQRSWSLPALYALPHAEQITRHICVEGWSAIGRWGGTPFREFLRRVGADTSAKYVGFKCADDYYESIDMATALHPQTLLAFEYDGKRLPPEYGFPMKLRMPTKLGYKNPKHIVEIFVTNAYPGGYWVDQGYNWFGGS
>NZ_CP004368.1|WP_160974052.1|3018536_3018749_-|hypothetical-protein
MLTKCGRHAAHVIIRVRLRVRSSPSVMFAAARSDLSFRTPPFPVIPVFPAPLAGGRIARRSTARRFTRAG
>NZ_CP004368.1|WP_004542991.1|3017597_3018533_-|EamA-family-transporter
MTPFDRFLAFVARHPPRLPQSRSGRVALALVFIYFAWGSTYLALHVALESFPPLLLSGLRNLLAGVGLFVFAMRRRPVRPTLVEIRNAALVGTMLVTMSSGLIALGMRTVSSGSAAVMVATVPLFATVIASVAGRRVTGGEWGAVALGMVGIVVLNSGGPSSPGSTLGSITVLAGALFWAGGAHLAARLALPHDLFLSTALQIGLGGAASTCIAWVLGERIGHVAWVPGAAFVYLMLAGTMAAYVAYGYLIRHTSPIIASSCMYVNPVVAVALGALLLGEPVTAATVIATIAILGSVGLSFVFDPARWRAQ
>NZ_CP004368.1|WP_004193486.1|3016049_3017246_+|MFS-transporter
MSSQPRHSAGTPGHYSRSLLLLLATIAGVSVANIYYNQPLLDAFRASFPGSASWIGVVPTATQLGYATGMLVLAPLGDRFDRRTLILLQIAGLSAALVVAAAAPTLGVLAAASLAIGILATIAQQAVPFAAEIAPPAARGQAVGTVMSGLLLGILLARTAAGFVAEYFGWRAVFAASVAALAALAAVIVARLPRSSPTSTLPYGKLLASMWQLVRELRGLREASMTGGAIFAAFSAFWPVLTLLLAGAPFHLGPQAAGLFGIVGAAGALAAPYAGRFADKRGPRAIISLAIALIAASFAIFALSGASLIGLVIGVIVLDVGVQAAQISNQSRIYALKPDARSRVNTVFMVCYFIGGAIGSSAGVAAWRATGWLGMCAVGLLFSIVAAIVHFRGGAGAR
>NZ_CP004368.1|WP_041188564.1|3027944_3029228_+|EAL-domain-containing-protein
MPKTQGFSPESLISQFTRCDAGWCVRYHDVTLASAFQPVISITHKRVVGYEALARATDANGAPISPDTLFARAQARGETILLDRLTRCLHVANFAAQDTGACWLFLNVLPQMFDAGISPGAFIEALCAHFALPPTRVVLEVIEQPSRNEVALARTIDMIQHGDFLIAVDDFGTGFSNFDRIWQIKPDIVKLDRSILERSLAASDAHRIIHHLVTMLHHAGTMVLAEGVENEDALQILMDADVDFVQGFCFGRPAPSLEHARRAAPARIEAAWRRFAERTKARCGDVVHPGFDTIERIMLTGAADYAQTRNLRDAAQRLLTSPIVRRVFVAEANGEQVEPSVAIETPEAPSATARRLAPLLPELHCNWSRRAYFQRAIAAPGRVALMGPHFSLTDGRDCYTAAVAIHLGTTLKVFCVDFDFSSYGDGR
>NZ_CP004368.1|WP_004193488.1|3029629_3030034_-|aminoacyl-tRNA-hydrolase
MTLRYAFSPDEVELTAVRAQGAGGQNVNKVSSAIHLRFDIRASSLPDDVKARLFARADQRITREGVIVIKAQEYRTQEKNRAAALARLDTLIRSAGVTPRKRVATRPTRASKERRLAEKGRRSEVKSGRGRVVE
>NZ_CP004368.1|WP_004543005.1|3030030_3032727_-|AAA-family-ATPase
MSVVDERFAWTGGLADRLPEPADFGLALAEGFARRIGMLSRRVGASAAAARWAARAAFAASRATAAGHVCVALRALAQRYDEPYDDVRAALAASGVTAFDGIVRGGECPLVVDRDGRLYLARYFEYETRLANALVERSRCGGAPAGGADALSPDALGERLVRYFGPQKERGVDWQRVAALIALTGRVTIVSGGPGTGKTTTVVGVIACLLDAHPELRIALAAPTGKAAQRMQEALHARAGSLPAELAARLPRTSCTLHRLLGGGPGGRFAHHRDNPLPYDLVVVDEASMIDVALAAHLLDALAPNARLVLLGDKDQLAAVEAGAVFAELSARPAFSPATCATIARALGVGEAEFVAALPDGFVVQAAGAERVADARAAAADMDAAARGTAGAAAAAARATAAAAARMTTAAAAARGAAPESAAQRAPAPHAGRRGGGRASNRTVDDAQGSLFAFDDDAFGVGTSGGEPGAGAQGAGRRDGGAPSLDGPHAGHRDGGASPGVAHSRRDAFDARARSGPADVSDVENAARAYAPAGAAGPADSPADASFVEPAAWIEADELAWLDNAVFSFSEGASANAEADGRRSAAATATDAGARTAPPVAREATAPTPRETARSDGSAVAPLTDCVVWLERNYRFGLDSPIGRLSLAIRRGAVQDALDALSTQDDAAARFSDDGGATLSAATVEQLARGFAGYAAALRDALATPEPDALPLFDVLNRFRVLCATRTGARGAEEVNARMAAEVRRAVRVPLALGAHWFAGRPVMVTRNDYALGLFNGDIGIALPGARGALRVWFRGADGRARAVSPAALPPHDTAFALTVHKSQGSEFDDAALILPASFNRVLSRELVYTAITRARARVQVIGSRAVLALAIATRTARDSGLAARIADALRARQEGAR
>NZ_CP004368.1|WP_004543008.1|3032723_3036536_-|exodeoxyribonuclease-V-subunit-beta
MSHVAPSGPSASELDVFACPLDGVNQIEASAGTGKTWNICALYVRLLLEKDLGADEILVVTFTKAATAELHERIRARLAQLAHALDTGDDGGDPFIARLFETTLAPERGLDPQTAAKRVRRALRAFDQAAIHTIHAFCQRALQEAPFAAAMPFAFEMEADDGVLRFELAADFWRTRVEPVAAAYPAFAEWLVEYGAGPAALDAQLARRLKKPLARLRWDGLHAADDGAESAARAHFDTAAAIWRDERGVLGTLLADAQPSLNQRSHKPEAVSEALDAWARYFEQASAVAALPRAALKLTQSALEKATKKGGATPRHAFFDVAQALEAAVAALEAAQRARWLSLVEQWLDAAPAELAQRKRTRRVVSFDDLLANLYRALDAHPWLRETLRARYPAALIDEFQDTDPLQFAIFDTIFAPAGPLFLVGDPKQAIYSFRAADLHTYLAARARASARYTLAVNQRSTPAIVGACNRVFGANPRAFVLDGLDYEPVRAGSRVRAPLVDATDPLAGAGDFRIWTLPAGDDVLTKRDAQRHAAHACAAEIARLMRGARERAVTLGGEPLAASGIAVLVQTHRQGSLVKRVLAAWGIGSVELAQASVFATIDAEQLERVLAAIDAPGDLRRLRSALASDWFGLDAAALWRLEQGDAEQDGIDAAARGASGNGGGARAASAGAPAPSPADADAMGWVERFSRYRLLWRERGFAVMWRTLAGELRIAERLMAGADGERRVTDVNHLAELTQARASAQPGIAPTLRWLAAQRLEGGGDDAQLRLESDRNLVQIVTVHKSKGLEYAIVFCPFLNDGGLREPAGSGLPDAREYHDESGCAVLHYGCDDEAAERASREAVREQAAERARLVYVALTRAVYRCYLVAGTYQSSRSTKEARRSVLNWLVAGAGRDFDAWLKEPPEDAELAERWQALAGGPVTLGALPVPAHREPLAAGHDAQATRAARRATRGLRDAWRIASFSSLASAIARDESGIARAADDEMRPDHDALAAALGADALEPPDAAAAIAPAPAAAPRELAEDDILAFPRGAAAGECLHRLLELSNFADASTWPPAALRALHERPVEAELALAERLPAMMTRLVADLAATELVPGMRLAALDPARRLTEMEFLFPAPALDFNALRRLLAAHGYPDVALEAGTLAGFVKGFIDMIVEHDGRFWIVDWKSNHLGTTPEAYGERALDAAMAHHAYHLQALLYMVALHRYLRVRMRGYDYDAHIAGYLYVFVRGVRPDWRNGGASAGVHARRPARALIEALDALMREGDA
>NZ_CP004368.1|WP_004521870.1|3036532_3039877_-|exodeoxyribonuclease-V-subunit-gamma
MLHLFYSNRHETLADALLDDLAFASDGAGPWAAQQVIVPSAALRRRLELDLAKRHGVCANVRFSYLAQWLWAQIGEVLTVPAHSPFAPDRLVWRCYRLLSDHGAAPWRASPRLAAYLAAADAPMRHELAHRIATVFDHYLTYRPEWLAQWQDGESIFALEGAPRHGGEAARDDEAWQAALWRALLAELSDSGMPPAHRFLREARAFDPDVIARARAKWPDAVSVFALPTMPPLHIALLRELSRWIDVRIYALNPCREFWFDIVTAARAESLDAADRLDYQEVGHPLLAEWGRQTQAQLHMLHELTESAAASDASRYADNPAPTWLARVQNAILDLQPEAALGEPPAERGVEVHVCHSLARQLEVLHDRLLAWFDADPSLAPSDVLVAMPDLATAGPLIDAVFGTPAGADAARIPYRITGLPPSQANPVARVLLDWLALPERDVGAPELVEWLRADAVAARYGIDATALETVQTWLAASGARRGLAPDAAEPPNPAVPAPRHTFADALTRLFLGYAMPDGAAPVSTWLPIAGAEGGEAELLGRLARFTDDLDGFARRIARDLTPQGWGDVFADALARFFDSGPAFADALSGVRDALDAMLAAMAEGAAGAALPAAVVRAGLAAALDDPARGGVPWGGVTFSSLTSLRGLPYRIVCLIGMDDGVLPSLARADEFDLMAVFAKLGDRQRRDDERNLFLDLLLAARERLLIAYTGRSIRDNAPLPPAALVDELLDHLAAASAGPDAPPDAVDAARRAFVIEHPLQPFSAEYFAPGGALFTYDASRATLARLLAEGARAQARPFFAAPLPAEPEQPVAFADFERFWRHPARSLLRARLGIVLLDAQAELVDTEPFELDYAGSDALAERVLPLLIETADAAAFEHALRVADASPEVPGGATGAVRRDHALDALAQLAGNVRRALADGATRVPFAFDVAPAWPAASDARWFGEHDAALAAAATREPLRLHGALARLTAAGQVIYRYARPGARDYLAAWLAHLVYCAIDPGGPRRTLWFGSGDTFEFAPVAAPLEQLAPLAALFRAGRRMPLAFFPRSAWALVSESESKAAGVWINDRVAGEADDASLALAWRGANPSLDEPFGALAHLVFDPLVEHLRRAS
>NZ_CP004368.1|WP_162473164.1|3040089_3040548_+|hypothetical-protein
MASANGRIASFGSLRERHHAPQSRGPLAALNRRRARRSESERRTPNAERRTPNAERRTPNAERRNAETPNAERRTPNAERRTPNAETPKRRNAERRTPNAERRTPNAERRTPNAERRTPNAERRTPNAERRTPNAERRTPAPKHGFRDAEIR
>NZ_CP004368.1|WP_004534567.1|3040604_3042881_+|hypothetical-protein
MRYSVEIRKFFYSQYFFGGLRIALGVSLPAVLSLAVLHDRELGFTIATGALGACVVDMPGPLKYKHNEMLACSVIGFFSALATGLATPNIFALWLTIVPLTFALSLIVVYGNRWPQISFATLFMMVMTLEEKFTPLQALVNASWILAGGLWYTYWATIVSRWQARRIEQQALAESLFACASYLLARADFYDLDADLDECYRNLVARQITAVETQETARDIVLRNLPKLRRGKLDPGRTMMFNLFINSVDLHEMFVGAHTDYPLVRSTFGGSDLMIFYRDLIRKAAADLEEIGFAVLENRLPHSRISVKAELRAIEYEIELMRKKQFAATHPEAYAAVLATFRRIWSATRLIDKMRRNLSGSADAQRTELKIDKALTRFLQKRRMSPLLIFSNLNMGSPSLRHALRVTIAVAVGFWLGRLLPLTNAYWIVMTSIIILKPGYSLTKQRNAQRIVGTLIGCAASLALIYTVHEPHVLIAIMFGSMVMSYSLLLFNYAASVVFTSSYVLLLFHLLAPGNMRIIGERAIDTVVGCMIAIAASRLFPYWEYRAIGKLVADALATTRKYFEATWRAGRGKAAPAVPAADGAAAVPAVAAVVDAVAPGLDGDYQYRLARKNVHIAFANLGQAFQRMMLEPKAHQKFVPELNDLLVQTHVLGAQITAAAPLLRHACEQGNPPALERGMAAVREHLEQAEAGVPPPANQAETSKQLTRELDSMVVDAERSDAGADLAHDLKVLAHQCKQMLASSLLIRKDASVIRLPE
>NZ_CP004368.1|WP_004192878.1|3042877_3043069_+|hypothetical-protein
MSRPPPPFLSTVSRRARTQGFPDYCPRASIGMIYPAPSCLYNFSSASAGPHRPADDTNHSETR
>NZ_CP004368.1|WP_004192513.1|3043065_3044430_+|amino-acid-permease
MKNLQRHLSARHIRFLALGSAIGTGLFYGSASAIRLAGPAVILAYIVGGAAVYMVMRALGEMAVREPVPGSFGHYATENLGPFAGFVTGWTYTLEMVIVAIADITAFGIYMGFWFPHVPQWIWVLAIVAIICGLNLCHVKVFGELEFWLSIVKVGAIVAMIGGGAAILFTGMRLGSGGAPSLANLWSHGGFLPNGVGGLVASLSVVIFAYGGIEVIGMSAGEAKEPERVIPRAINAVPMRILLFYVLTMIVLMSIFPWTGVGANGSPFVQIFSALGVRSAAEILNLVVISAAISAINSDIFGAGRMMYAMALQGQAPRALAAMSARGVPWVTVLVMAGALLVGVVLNYLMPKDVFLMVAASATFATVWVWLMILLSQVAMRRRLGAAEVAALKFKVPFWPVGPALTIAFMAFVIAMLGYFDDTRVALFVGAAWLAILALVFYTRIRPRLAAVAR
>NZ_CP004368.1|WP_004193167.1|3044591_3044771_-|hypothetical-protein
MNDPRSKKNPVFGVAILIVVVIALVIGTILYNAISQKHEYDEAHPHAASAASAASAQHG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

181900 : 247087

Streptococcus_phage(12.5%)

portal,transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020850758.1\|181900_183364_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	1.2e-79	38.3
WP_004199069.1\|183468_184656_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	2.2e-121	60.7
WP_004523078.1\|184921_185806_+	lipid A biosynthesis lauroyl acyltransferase	A0A1W6JP29	Morganella_phage	7.3e-29	30.1
WP_004199067.1\|185846_186716_+	diaminopimelate epimerase	NA	NA	NA	NA
WP_020850774.1\|186763_187477_+	DUF484 family protein	NA	NA	NA	NA
WP_004523080.1\|187514_188447_+	tyrosine recombinase XerC	G1JX48	Mycobacterium_phage	2.4e-14	28.0
WP_004542863.1\|188535_189813_+	class I SAM-dependent rRNA methyltransferase	NA	NA	NA	NA
WP_009972676.1\|189990_191076_+	GTP-binding protein	NA	NA	NA	NA
WP_004198318.1\|191625_192042_+	RNA polymerase-binding protein DksA	NA	NA	NA	NA
WP_004203414.1\|192296_192833_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_004198316.1\|192842_194186_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	3.7e-40	28.8
WP_004198315.1\|194612_195155_-	response regulator transcription factor	NA	NA	NA	NA
WP_004198314.1\|195174_196455_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_004198312.1\|196472_196724_-	cysteine-rich CWC family protein	NA	NA	NA	NA
WP_004200214.1\|197048_197948_+	acetylglutamate kinase	NA	NA	NA	NA
WP_004198307.1\|197944_198748_+	pyrimidine 5'-nucleotidase	NA	NA	NA	NA
WP_004525865.1\|198714_199407_+	nucleoid occlusion factor SlmA	NA	NA	NA	NA
WP_004198305.1\|199756_200902_+	homoserine O-acetyltransferase	NA	NA	NA	NA
WP_004543091.1\|200898_201513_+	methionine biosynthesis protein MetW	NA	NA	NA	NA
WP_004523086.1\|201524_202838_+	AmpG family muropeptide MFS transporter	NA	NA	NA	NA
WP_004535313.1\|202827_203880_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_004525862.1\|204252_205197_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004523088.1\|205408_206473_+	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L339	Tupanvirus	1.3e-80	45.8
WP_004191998.1\|206740_208204_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004190029.1\|208364_209135_-	exodeoxyribonuclease III	R4TWA8	Phaeocystis_globosa_virus	3.4e-30	33.8
WP_004523089.1\|209167_210007_-	polyphosphate kinase	NA	NA	NA	NA
WP_004523090.1\|210133_211606_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_004525859.1\|211608_213099_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_004189769.1\|213211_213511_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_004189550.1\|213876_214920_+	rod shape-determining protein	NA	NA	NA	NA
WP_004189331.1\|215039_216113_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_004523092.1\|216109_216622_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_004543095.1\|216805_219217_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_004189171.1\|219228_220377_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_004543106.1\|220642_221419_-	sel1 repeat family protein	NA	NA	NA	NA
WP_004189570.1\|221415_222201_-	2-dehydro-3-deoxyglucarate aldolase	NA	NA	NA	NA
WP_004189793.1\|222625_223078_-	6-carboxytetrahydropterin synthase QueD	A0A088FAL2	Vibrio_phage	7.6e-14	30.8
WP_004189241.1\|223097_223730_-	7-carboxy-7-deazaguanine synthase	R4TAH8	Halovirus	2.1e-06	30.9
WP_004190026.1\|223823_224558_-	7-cyano-7-deazaguanine synthase QueC	A0A1B0Z0B4	Vibrio_phage	1.6e-50	42.5
WP_004189647.1\|225025_225709_-	response regulator	NA	NA	NA	NA
WP_004523096.1\|225709_228118_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_004543101.1\|228119_228710_-	DUF4390 domain-containing protein	NA	NA	NA	NA
WP_020850535.1\|228706_230116_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_004189409.1\|230667_231525_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_004543107.1\|231634_232270_-	LysE family translocator	NA	NA	NA	NA
WP_004543102.1\|232390_233374_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.3e-07	38.0
WP_004525852.1\|233405_233909_-	peptide deformylase	A0A067XQZ3	Caulobacter_phage	2.1e-12	34.3
WP_020850823.1\|234137_235328_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	2.0e-21	39.2
WP_004190199.1\|235387_235759_+	thioredoxin family protein	NA	NA	NA	NA
WP_004523103.1\|235969_238579_+	DNA topoisomerase III	A0A2P1ELA0	Moumouvirus	7.7e-18	25.7
WP_004189230.1\|238802_239858_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004523104.1\|240296_241313_+	D-2-hydroxyacid dehydrogenase family protein	NA	NA	NA	NA
WP_004543112.1\|241433_242303_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_004200732.1\|242340_242745_-	PaaI family thioesterase	NA	NA	NA	NA
WP_004543096.1\|243618_244623_+	hypothetical protein	NA	NA	NA	NA
WP_004200731.1\|245159_245642_+	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_004523107.1\|245638_245923_+	hypothetical protein	NA	NA	NA	NA
WP_004543108.1\|245995_247087_-\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	2.2e-192	91.7

DBSCAN-SWA_2

461631 : 472850

Shigella_phage(20.0%)

integrase

attL 459044:459061|attR 475630:475647

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
459044:459061	attL	NA	NA	NA	NA
WP_004524472.1\|461631_463719_+	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	1.9e-99	35.8
WP_004202928.1\|464041_464941_-	cytochrome c	NA	NA	NA	NA
WP_041188602.1\|466123_466711_+\|integrase	site-specific integrase	A0A0S2SYQ7	Pseudomonas_phage	3.1e-44	50.6
WP_009932253.1\|466762_467083_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	1.0e-12	58.6
WP_009922658.1\|467090_467408_+	helix-turn-helix transcriptional regulator	A0A088CD40	Shigella_phage	6.2e-15	57.0
WP_004541800.1\|467407_468325_+	DUF4935 domain-containing protein	A4PE40	Ralstonia_virus	8.9e-46	40.6
WP_009922654.1\|468578_469121_+	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	3.3e-48	56.4
WP_009932249.1\|469378_469831_+	VRR-NUC domain-containing protein	Q8W6S1	Burkholderia_virus	2.3e-31	58.8
WP_004525722.1\|469830_470910_+	DUF3396 domain-containing protein	A9YX32	Burkholderia_phage	2.2e-160	99.0
WP_004525721.1\|471066_471315_+	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	4.0e-41	97.6
WP_004195754.1\|472205_472850_+	chitin-binding protein	A0A0K1Y848	Apis_mellifera_filamentous_virus	5.7e-07	30.4
475630:475647	attR	NA	NA	NA	NA

DBSCAN-SWA_3

717106 : 743668

Burkholderia_phage(44.44%)

integrase,protease,plate,tail

attL 717679:717725|attR 733156:733202

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004527881.1\|717106_717628_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.9e-21	51.0
717679:717725	attL	NA	NA	NA	NA
WP_004542707.1\|717821_718868_+\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	3.9e-53	38.7
WP_004542657.1\|720630_720885_+	hypothetical protein	NA	NA	NA	NA
WP_004542680.1\|720898_721549_+	hypothetical protein	NA	NA	NA	NA
WP_020850759.1\|721560_721953_+	hypothetical protein	NA	NA	NA	NA
WP_004542725.1\|721945_722794_+	type IV secretion system protein	NA	NA	NA	NA
WP_143291333.1\|722853_723105_+	hypothetical protein	NA	NA	NA	NA
WP_004542660.1\|723257_723539_+	hypothetical protein	NA	NA	NA	NA
WP_004542720.1\|723957_726933_+	conjugative relaxase	V5UQN3	Mycobacterium_phage	4.5e-06	28.8
WP_020850657.1\|726958_727210_-	hypothetical protein	NA	NA	NA	NA
WP_076847806.1\|727684_728131_+	hypothetical protein	NA	NA	NA	NA
WP_004542662.1\|728127_728397_+	hypothetical protein	NA	NA	NA	NA
WP_020850845.1\|728413_729073_+	hypothetical protein	NA	NA	NA	NA
WP_004542700.1\|729185_730100_-	three-Cys-motif partner protein TcmP	NA	NA	NA	NA
WP_076847687.1\|730111_730954_-	phage Gp37/Gp68 family protein	Q8W6R4	Burkholderia_virus	2.9e-67	43.3
WP_076847807.1\|731248_731887_+	DUF4433 domain-containing protein	NA	NA	NA	NA
WP_020850538.1\|731901_732963_+	macro domain-containing protein	B3FJ30	Pseudomonas_phage	3.1e-18	36.5
WP_004542696.1\|733805_734132_+\|plate	baseplate J-like protein, truncation	K4NZR5	Burkholderia_phage	1.3e-52	100.0
733156:733202	attR	NA	NA	NA	NA
WP_004542714.1\|734124_734538_+\|tail	phage tail protein I	K4NXA0	Burkholderia_phage	1.5e-69	99.2
WP_020850622.1\|734555_735038_+	DNA methylase	K4NZW3	Burkholderia_phage	4.5e-73	87.6
WP_111952238.1\|735431_736022_+	hypothetical protein	NA	NA	NA	NA
WP_004542688.1\|736125_736491_-	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	5.1e-53	89.3
WP_004521948.1\|736592_737378_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004521949.1\|737374_738721_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004521950.1\|738829_739444_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004531875.1\|739818_740490_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004521952.1\|740526_741045_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004521953.1\|741061_742552_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004527837.1\|742624_743128_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004204912.1\|743185_743668_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_4

1094946 : 1104191

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004194034.1\|1094946_1096899_+	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2
WP_004533593.1\|1097165_1098296_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	3.8e-22	27.6
WP_004541188.1\|1098329_1100336_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	4.8e-52	34.6
WP_004194137.1\|1100519_1101335_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004532195.1\|1101399_1102083_-	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.0e-05	26.0
WP_004194373.1\|1102079_1102607_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004541275.1\|1102643_1104191_-	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	1.2e-23	30.9

DBSCAN-SWA_5

1442944 : 1451759

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004522358.1\|1442944_1444345_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.9e-79	38.5
WP_009921652.1\|1444376_1445300_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.3e-15	27.1
WP_004190173.1\|1445358_1446351_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_004539941.1\|1446422_1446740_+	competence protein ComE	NA	NA	NA	NA
WP_004532363.1\|1447063_1447966_+	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	1.9e-53	39.9
WP_004539874.1\|1448192_1449476_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004522362.1\|1449654_1450578_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	2.4e-43	36.2
WP_041188594.1\|1450916_1451759_-	alpha/beta hydrolase	A7XCB7	Tanapox_virus	7.2e-18	27.0

DBSCAN-SWA_6

1526920 : 1606158

Burkholderia_virus(30.3%)

portal,protease,terminase,holin,integrase,tail,head

attL 1533466:1533483|attR 1556256:1556273

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004192020.1\|1526920_1528429_+\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	2.8e-20	27.7
WP_004539792.1\|1528425_1528680_+	glutaredoxin family protein	NA	NA	NA	NA
WP_004527467.1\|1528687_1528930_-	hypothetical protein	NA	NA	NA	NA
WP_004193305.1\|1528921_1530715_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	2.1e-22	23.5
WP_004193513.1\|1530730_1531624_+	signal peptidase I	NA	NA	NA	NA
WP_004539775.1\|1531774_1533178_+	ribonuclease III	G8DDA3	Micromonas_pusilla_virus	4.9e-19	30.3
WP_004191678.1\|1533247_1534147_+	GTPase Era	NA	NA	NA	NA
1533466:1533483	attL	NA	NA	NA	NA
WP_004524618.1\|1534166_1534994_+	DNA repair protein RecO	NA	NA	NA	NA
WP_004192885.1\|1534990_1535764_+	pyridoxine 5'-phosphate synthase	NA	NA	NA	NA
WP_004191194.1\|1535769_1536201_+	holo-ACP synthase	NA	NA	NA	NA
WP_004539664.1\|1536228_1537257_+	beta-N-acetylhexosaminidase	NA	NA	NA	NA
WP_004192300.1\|1537370_1538768_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_004193484.1\|1539039_1539597_-	elongation factor P	NA	NA	NA	NA
WP_004540031.1\|1539786_1541007_-	elongation factor P maturation arginine rhamnosyltransferase EarP	NA	NA	NA	NA
WP_004527460.1\|1541230_1543474_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_004192722.1\|1543601_1544195_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_004539938.1\|1544959_1546159_+\|integrase	site-specific integrase	A0A1L7DQ84	Ralstonia_phage	7.9e-18	34.7
WP_080002859.1\|1546175_1547123_-	conjugal transfer protein TraN	NA	NA	NA	NA
WP_004539756.1\|1547166_1547493_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_020850651.1\|1547489_1547750_-	hypothetical protein	NA	NA	NA	NA
WP_041188621.1\|1547746_1548091_-	hypothetical protein	X5I2N5	Pseudomonas_phage	6.7e-31	71.0
WP_076847822.1\|1549370_1549709_-	hypothetical protein	NA	NA	NA	NA
WP_004539721.1\|1549810_1551127_-	hypothetical protein	NA	NA	NA	NA
WP_004539952.1\|1551126_1551573_-	hypothetical protein	NA	NA	NA	NA
WP_004539947.1\|1551569_1551929_-	hypothetical protein	NA	NA	NA	NA
WP_020850499.1\|1551933_1552143_-	hypothetical protein	NA	NA	NA	NA
WP_004539642.1\|1552150_1552303_-	hypothetical protein	NA	NA	NA	NA
WP_020850728.1\|1552305_1552521_-	hypothetical protein	NA	NA	NA	NA
WP_020850435.1\|1553087_1553615_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004539980.1\|1553708_1553915_+	hypothetical protein	NA	NA	NA	NA
WP_020850469.1\|1553989_1554514_+	hypothetical protein	C7BGG0	Burkholderia_phage	6.2e-28	45.0
WP_004540057.1\|1554522_1554915_+	hypothetical protein	NA	NA	NA	NA
WP_004539611.1\|1555069_1557808_+	virulence protein E	A0A2D1GN57	Marinobacter_phage	1.1e-91	43.3
1556256:1556273	attR	NA	NA	NA	NA
WP_076847724.1\|1558087_1558885_+	hypothetical protein	NA	NA	NA	NA
WP_004539817.1\|1559103_1559862_+	hypothetical protein	A0A1B0Z000	Pseudomonas_phage	5.0e-34	42.7
WP_020850831.1\|1560043_1560673_+	hypothetical protein	A0A2H4JCL4	uncultured_Caudovirales_phage	1.6e-06	32.3
WP_020850857.1\|1560620_1562690_+\|terminase	phage terminase large subunit family protein	A0A1B2LRQ2	Wolbachia_phage	1.3e-100	34.0
WP_004540003.1\|1562692_1562899_+	hypothetical protein	A0A2H4JA19	uncultured_Caudovirales_phage	6.5e-05	46.8
WP_004539741.1\|1562900_1564424_+\|portal	phage portal protein	B7SYD6	Stenotrophomonas_phage	1.2e-84	38.6
WP_020850433.1\|1564413_1566492_+\|head,protease	caudovirus prohead protease family protein	A0A076G7Y9	Pseudoalteromonas_phage	1.9e-67	29.8
WP_004540064.1\|1566557_1566893_+	DUF2190 family protein	NA	NA	NA	NA
WP_004539750.1\|1566895_1567192_+	hypothetical protein	NA	NA	NA	NA
WP_004539916.1\|1567188_1567614_+	hypothetical protein	NA	NA	NA	NA
WP_020850716.1\|1567644_1568583_+	hypothetical protein	G8CLB2	Synechococcus_phage	9.7e-48	36.8
WP_004540052.1\|1568641_1568980_+	hypothetical protein	F4YCS5	Synechococcus_phage	1.8e-07	29.1
WP_043944506.1\|1569051_1569357_+	hypothetical protein	A0A0H5ARS5	Pseudomonas_phage	7.6e-10	44.3
WP_004539854.1\|1569401_1572182_+\|tail	tail tape measure protein	C4ML16	Xanthomonas_virus	1.3e-18	26.1
WP_076847725.1\|1572171_1572510_+\|tail	phage tail protein	K7PHL4	Enterobacterial_phage	2.4e-17	42.3
WP_020850804.1\|1572511_1573915_+\|tail	tail fiber domain-containing protein	Q8W6T4	Burkholderia_virus	3.0e-194	75.9
WP_004539780.1\|1573911_1574604_+\|tail	phage minor tail protein L	Q6JIL5	Burkholderia_virus	2.9e-81	65.0
WP_004539701.1\|1574608_1575340_+	C40 family peptidase	Q8W6T2	Burkholderia_virus	1.3e-63	50.4
WP_004539859.1\|1575336_1575918_+\|tail	tail assembly protein	Q3HQU4	Burkholderia_phage	6.9e-52	55.7
WP_004540110.1\|1575914_1579286_+	host specificity protein J	A4JX16	Burkholderia_virus	2.8e-302	48.3
WP_020850420.1\|1579285_1579591_+	hypothetical protein	Q8W6S9	Burkholderia_virus	1.6e-39	73.5
WP_020850642.1\|1579590_1580328_+	hypothetical protein	Q8W6S8	Burkholderia_virus	2.8e-98	68.0
WP_004539903.1\|1580385_1580670_+\|holin	holin	C7BGD7	Burkholderia_phage	4.7e-38	90.4
WP_020850783.1\|1580672_1581167_+	glycoside hydrolase family 104 protein	Q6J1Q5	Burkholderia_virus	6.9e-69	79.9
WP_004540004.1\|1581163_1581658_+	DUF2514 family protein	Q6J1Q4	Burkholderia_virus	6.7e-32	54.5
WP_004539787.1\|1581825_1582614_+	DNA adenine methylase	Q8W6S4	Burkholderia_virus	6.1e-144	90.5
WP_004540087.1\|1582724_1583612_+	hypothetical protein	Q8W6S3	Burkholderia_virus	2.1e-92	64.1
WP_004539830.1\|1583718_1584108_-	hypothetical protein	NA	NA	NA	NA
WP_041188619.1\|1584145_1584406_-	hypothetical protein	C7BGE3	Burkholderia_phage	2.8e-37	83.7
WP_144084165.1\|1584370_1584874_+	DUF159 family protein	A0A1S5NTJ1	Burkholderia_phage	8.3e-70	85.8
WP_004539946.1\|1584914_1585856_-	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_158332260.1\|1586000_1586063_+	hypothetical protein	NA	NA	NA	NA
WP_004193834.1\|1587318_1587831_-	GAF domain-containing protein	NA	NA	NA	NA
WP_004197652.1\|1587995_1588904_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004191946.1\|1589030_1589897_+	pirin family protein	NA	NA	NA	NA
WP_004554230.1\|1590138_1590642_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004191283.1\|1590776_1591649_-	cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_004192175.1\|1591659_1592106_-	copper chaperone PCu(A)C	NA	NA	NA	NA
WP_020850745.1\|1592132_1592792_-	SCO family protein	NA	NA	NA	NA
WP_076847727.1\|1592997_1593219_-	hypothetical protein	NA	NA	NA	NA
WP_004550148.1\|1593208_1593961_+	trehalose-phosphatase	NA	NA	NA	NA
WP_004203013.1\|1593957_1595334_+	alpha,alpha-trehalose-phosphate synthase (UDP-forming)	NA	NA	NA	NA
WP_004539709.1\|1595395_1597267_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.7e-38	27.1
WP_004192961.1\|1597833_1598898_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_004535747.1\|1599164_1600136_+	hypothetical protein	NA	NA	NA	NA
WP_004204640.1\|1600191_1600653_+	DUF2214 family protein	NA	NA	NA	NA
WP_004524631.1\|1600802_1601975_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_004191212.1\|1602073_1603222_-	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004191603.1\|1604055_1606158_-\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA

DBSCAN-SWA_7

1756736 : 1849117

102

uncultured_Caudovirales_phage(22.73%)

plate,portal,protease,capsid,terminase,tail,integrase,tRNA,head

attL 1765508:1765526|attR 1823689:1823707

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004192783.1\|1756736_1758263_-\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	2.8e-84	35.6
WP_004199566.1\|1758356_1759461_-	peptide chain release factor 2	A0A0S4KWG0	Pseudomonas_phage	2.2e-06	37.1
WP_004191649.1\|1759800_1761495_-	single-stranded-DNA-specific exonuclease RecJ	A0A0K2FM92	Brevibacillus_phage	1.1e-28	27.3
WP_004193226.1\|1761510_1762587_-	hypothetical protein	NA	NA	NA	NA
WP_004540060.1\|1763154_1764408_+	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_004195923.1\|1764400_1765150_+	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	2.2e-34	38.3
WP_004192516.1\|1765154_1765943_+	TatD family hydrolase	NA	NA	NA	NA
1765508:1765526	attL	NA	NA	NA	NA
WP_020850592.1\|1765995_1768524_+	DNA internalization-related competence protein ComEC/Rec2	NA	NA	NA	NA
WP_004540067.1\|1768560_1769388_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004192790.1\|1769644_1771306_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.9e-150	52.0
WP_004539923.1\|1771302_1772157_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	8.9e-48	40.9
WP_004192585.1\|1772260_1773544_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	6.4e-151	62.6
WP_004191789.1\|1773635_1774067_+	cell division protein FtsB	NA	NA	NA	NA
WP_004532146.1\|1774292_1774640_-	hypothetical protein	NA	NA	NA	NA
WP_004191092.1\|1774723_1775674_-	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_004524734.1\|1775712_1776237_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_004191514.1\|1776446_1777265_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_004192762.1\|1777419_1778310_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_004193008.1\|1778577_1779408_+	PHP domain-containing protein	NA	NA	NA	NA
WP_004192132.1\|1779472_1780102_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_004192745.1\|1780200_1780866_+\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_004191887.1\|1780874_1782077_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_004192474.1\|1782073_1782691_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004191516.1\|1782735_1783638_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_004524737.1\|1783748_1784891_+	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_004193059.1\|1784895_1785672_+	MBL fold metallo-hydrolase	U5PVD0	Bacillus_phage	3.3e-09	26.6
WP_004539920.1\|1786398_1787586_-	cupin domain-containing protein	NA	NA	NA	NA
WP_004524740.1\|1787654_1788200_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_004540138.1\|1788179_1789478_-	hypothetical protein	NA	NA	NA	NA
WP_004539925.1\|1789464_1792149_-	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	9.3e-27	24.3
WP_004539636.1\|1792308_1793610_+\|integrase	integrase family protein	C7BGE7	Burkholderia_phage	1.8e-148	58.9
WP_009890227.1\|1793560_1793803_-	AlpA family phage regulatory protein	C7BGF0	Burkholderia_phage	9.3e-19	59.2
WP_004539932.1\|1793811_1794285_-	hypothetical protein	B5TA88	Burkholderia_phage	2.3e-05	71.4
WP_004555250.1\|1794293_1794623_-	hypothetical protein	NA	NA	NA	NA
WP_004540046.1\|1794736_1796053_-	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_004539832.1\|1796052_1796502_-	hypothetical protein	NA	NA	NA	NA
WP_004534172.1\|1796498_1797104_-	hypothetical protein	NA	NA	NA	NA
WP_004539634.1\|1797100_1797436_-	hypothetical protein	NA	NA	NA	NA
WP_128972336.1\|1797487_1797676_-	NlpBDapX lipoprotein	NA	NA	NA	NA
WP_004555253.1\|1797810_1798299_-	hypothetical protein	NA	NA	NA	NA
WP_004555254.1\|1798252_1798753_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_024430958.1\|1798869_1799079_+	hypothetical protein	NA	NA	NA	NA
WP_009944042.1\|1799165_1799696_+	hypothetical protein	C7BGG0	Burkholderia_phage	4.4e-29	46.8
WP_024464805.1\|1799709_1800063_+	hypothetical protein	NA	NA	NA	NA
WP_004539945.1\|1800369_1800840_+	hypothetical protein	NA	NA	NA	NA
WP_004540079.1\|1800959_1803452_+	virulence protein E	A0A2D1GN57	Marinobacter_phage	3.6e-97	41.8
WP_020850498.1\|1803661_1804249_+	hypothetical protein	NA	NA	NA	NA
WP_041188588.1\|1804596_1804971_+	hypothetical protein	NA	NA	NA	NA
WP_020850524.1\|1805337_1805907_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004552756.1\|1805869_1807855_+\|terminase	phage terminase large subunit family protein	A0A2D1GMT1	Marinobacter_phage	2.1e-180	53.4
WP_004533700.1\|1807865_1808072_+	hypothetical protein	NA	NA	NA	NA
WP_020850457.1\|1808068_1809562_+\|portal	phage portal protein	A0A2H4JFL5	uncultured_Caudovirales_phage	4.4e-135	51.2
WP_004540078.1\|1809558_1810638_+\|protease	Clp protease ClpP	A0A2H4JDI2	uncultured_Caudovirales_phage	1.6e-46	37.1
WP_004539732.1\|1810664_1811009_+\|head	head decoration protein	NA	NA	NA	NA
WP_080002857.1\|1811043_1812069_+\|capsid	major capsid protein	A0A2H4J890	uncultured_Caudovirales_phage	8.3e-109	58.8
WP_004539695.1\|1812072_1812363_+	hypothetical protein	NA	NA	NA	NA
WP_004539763.1\|1812364_1812895_+\|tail	phage tail protein	A0A2H4JBV1	uncultured_Caudovirales_phage	9.2e-11	28.0
WP_020850797.1\|1812884_1813418_+	hypothetical protein	Q9JML9	Wolbachia_phage	1.4e-22	39.5
WP_004539840.1\|1813420_1814101_+\|plate	phage baseplate assembly protein V	A0A1B2LRU5	Wolbachia_phage	1.2e-18	34.4
WP_004539700.1\|1814165_1814372_+	hypothetical protein	NA	NA	NA	NA
WP_004539881.1\|1814368_1814713_+	hypothetical protein	A0A2H4JA09	uncultured_Caudovirales_phage	3.0e-23	50.0
WP_004533630.1\|1814709_1815603_+\|plate	baseplate J protein	D5LGZ3	Escherichia_phage	1.9e-48	40.7
WP_004539949.1\|1815595_1816171_+\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	6.0e-32	47.7
WP_004539647.1\|1816158_1817622_+	hypothetical protein	A4JWL8	Burkholderia_virus	8.0e-214	77.8
WP_004539865.1\|1817637_1818090_+\|tail	tail assembly chaperone	A4JWL9	Burkholderia_virus	1.8e-44	76.8
WP_004539720.1\|1818155_1819325_+\|tail	phage tail sheath family protein	A0A2H4J869	uncultured_Caudovirales_phage	6.9e-160	72.9
WP_004540135.1\|1819335_1819839_+\|tail	phage major tail tube protein	Q7M2A5	Pseudomonas_phage	1.6e-41	50.6
WP_004533642.1\|1819908_1820211_+\|tail	phage tail assembly protein	V5YST8	Pseudomonas_phage	1.5e-05	37.2
WP_004539677.1\|1820298_1822713_+\|tail	phage tail tape measure protein	A0A2H4JG00	uncultured_Caudovirales_phage	6.4e-67	34.3
WP_004539752.1\|1822721_1823603_+\|tail	phage tail protein	A0A2H4J875	uncultured_Caudovirales_phage	3.9e-30	37.4
WP_004540041.1\|1823577_1823784_+\|tail	phage tail protein	A0A2H4J9Z9	uncultured_Caudovirales_phage	4.0e-15	61.2
1823689:1823707	attR	NA	NA	NA	NA
WP_004539808.1\|1823793_1824846_+	phage late control protein	A0A2H4JBF6	uncultured_Caudovirales_phage	1.7e-77	44.5
WP_004533694.1\|1824921_1825116_+	hypothetical protein	NA	NA	NA	NA
WP_004539628.1\|1825108_1825606_+	lysozyme	A4JX20	Burkholderia_virus	2.2e-67	78.2
WP_004539940.1\|1825605_1826151_+	lysozyme	Q8W6S5	Burkholderia_virus	6.4e-84	96.7
WP_004540080.1\|1826294_1827083_+	DNA adenine methylase	Q8W6S4	Burkholderia_virus	6.1e-152	97.7
WP_004539736.1\|1827123_1827834_-	hypothetical protein	A4PE26	Ralstonia_virus	1.4e-38	41.5
WP_038732294.1\|1827845_1828361_-	hypothetical protein	NA	NA	NA	NA
WP_020850500.1\|1828332_1828806_-	hypothetical protein	NA	NA	NA	NA
WP_004539924.1\|1828798_1829305_-	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	5.1e-19	39.4
WP_004539640.1\|1829301_1829727_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	4.9e-15	49.4
WP_020850431.1\|1830124_1830505_-	hypothetical protein	NA	NA	NA	NA
WP_004540114.1\|1830964_1831192_-	hypothetical protein	NA	NA	NA	NA
WP_133604798.1\|1831188_1831587_-	hypothetical protein	NA	NA	NA	NA
WP_004540053.1\|1832239_1832701_+	excisionase family DNA-binding protein	K4ICM4	Acidithiobacillus_phage	6.7e-50	67.3
WP_004539802.1\|1832705_1833281_+	PIN domain-containing protein	K4HZX4	Acidithiobacillus_phage	5.4e-73	70.4
WP_004540097.1\|1833466_1835683_+	ATP-binding protein	NA	NA	NA	NA
WP_004524743.1\|1836159_1836387_+	hypothetical protein	NA	NA	NA	NA
WP_004191077.1\|1836931_1837111_+	hypothetical protein	NA	NA	NA	NA
WP_004527347.1\|1837294_1837567_+	hypothetical protein	NA	NA	NA	NA
WP_004191664.1\|1837835_1838639_-	inositol monophosphatase	NA	NA	NA	NA
WP_004524745.1\|1838682_1838934_+	hypothetical protein	NA	NA	NA	NA
WP_004539789.1\|1838939_1839851_+	RNA methyltransferase	NA	NA	NA	NA
WP_004539737.1\|1840041_1840827_+	serine O-acetyltransferase	NA	NA	NA	NA
WP_020850718.1\|1841162_1841963_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_004193779.1\|1841987_1842479_-	peptidyl-prolyl cis-trans isomerase	A0A1V0SCU1	Indivirus	4.2e-10	33.3
WP_004191635.1\|1842559_1843135_-	peptidyl-prolyl cis-trans isomerase	A0A1V0SCU1	Indivirus	5.3e-12	39.3
WP_004195907.1\|1843191_1843914_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004192752.1\|1844145_1845543_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	1.8e-42	33.8
WP_004205123.1\|1845590_1846529_+	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004193249.1\|1846632_1847604_+	acetyl-CoA carboxylase carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_004538130.1\|1847647_1849117_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA

DBSCAN-SWA_8

2042275 : 2050468

Burkholderia_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004196630.1\|2042275_2042539_+	hypothetical protein	Q8W6S4	Burkholderia_virus	2.2e-26	85.5
WP_076839978.1\|2042522_2042708_+	hypothetical protein	Q8W6S4	Burkholderia_virus	5.8e-21	83.3
WP_009920998.1\|2042728_2043454_-	hypothetical protein	A4PE26	Ralstonia_virus	5.8e-32	44.0
WP_004539879.1\|2044403_2044910_-	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	1.3e-19	40.9
WP_004539795.1\|2044906_2045332_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	3.8e-15	49.4
WP_009937072.1\|2045612_2046008_-	hypothetical protein	NA	NA	NA	NA
WP_009919883.1\|2046259_2046487_+	hypothetical protein	Q8W6S4	Burkholderia_virus	4.2e-21	72.7
WP_004527234.1\|2046522_2046756_-	hypothetical protein	A4PE26	Ralstonia_virus	4.3e-13	60.6
WP_004550288.1\|2046831_2047293_-	avidin	NA	NA	NA	NA
WP_004193710.1\|2048231_2048414_+	hypothetical protein	NA	NA	NA	NA
WP_004193371.1\|2048540_2049164_-	phospholipase D family protein	NA	NA	NA	NA
WP_004539691.1\|2049358_2050468_-	class II histone deacetylase	A0A2K9L2T7	Tupanvirus	1.6e-36	31.3

DBSCAN-SWA_9

3475495 : 3486439

Agrobacterium_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004196461.1\|3475495_3477796_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.1e-167	42.1
WP_004194131.1\|3477792_3478107_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6
WP_004196460.1\|3478639_3478843_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004541727.1\|3478972_3480583_-	multicopper oxidase family protein	NA	NA	NA	NA
WP_004189626.1\|3480595_3480778_+	hypothetical protein	NA	NA	NA	NA
WP_004189552.1\|3480750_3482010_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_004189780.1\|3482277_3482856_+	pseudouridine synthase	NA	NA	NA	NA
WP_071810810.1\|3483117_3483336_+	hypothetical protein	NA	NA	NA	NA
WP_004530837.1\|3483527_3484037_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.5e-13	41.2
WP_004197486.1\|3484324_3486439_+	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP004369

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP004368

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection