CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007410	Pseudomonas brassicacearum strain DF41 chromosome, complete genome	2 crisprs	PD-DExK,DEDDh,csa3,DinG,cas3,WYL	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007410_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007410_1

1956747-1956858

Orphan

Consensus_repeat	Method
TGTGGGAGCGAGCCTGCTCGCGAAGGCGGCCTGACAGCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007410_1

>merge|NZ_CP007410|1|1956747-1956858|CRISPRCasFinder
TGTGGGAGCGAGCCTGCTCGCGAAGGCGGCCTGACAGCCGGCCTGTTTCTTGCGGCTGTACTCCGATCCCCTTGTGGGAGCGAGCCTGCTTGCGAAGGCGGCCTGACAGCCG

>NZ_CP007410|1|1|1956747-1956858|CRISPRCasFinder
TGTGGGAGCGAGCCTGCTCGCGAAGGCGGCCTGACAGCCG	GCCTGTTTCTTGCGGCTGTACTCCGATCCCCT
TGTGGGAGCGAGCCTGCTTGCGAAGGCGGCCTGACAGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007410.1\|WP_025212602.1\|1953295_1954105_-\|preprotein-translocase-subunit-TatD	unknown	unknown	gnl\|CDD\|182449
NZ_CP007410.1\|WP_025212604.1\|1955858_1956293_+\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP007410.1\|WP_025212607.1\|1958479_1960984_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|225669
NZ_CP007410.1\|WP_025212610.1\|1962868_1963840_+\|L,D-transpeptidase-family-protein	unknown	unknown	gnl\|CDD\|182341
NZ_CP007410.1\|WP_003199355.1\|1963963_1964215_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007410.1\|WP_025212599.1\|1950297_1951095_+\|thioesterase-family-protein	unknown	unknown	gnl\|CDD\|379298
NZ_CP007410.1\|WP_025212603.1\|1954339_1955761_+\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|226971
NZ_CP007410.1\|WP_025212606.1\|1957947_1958445_-\|transcription-elongation-factor-GreB	unknown	unknown	gnl\|CDD\|179345
NZ_CP007410.1\|WP_025212595.1\|1946785_1947484_+\|response-regulator	unknown	unknown	gnl\|CDD\|182522
NZ_CP007410.1\|WP_025212597.1\|1948906_1949197_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007410.1\|WP_025212594.1\|1944085_1946737_+\|sensor-histidine-kinase-KdpD	unknown	unknown	gnl\|CDD\|225115
NZ_CP007410.1\|WP_003183779.1\|1964849_1965131_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|379642
NZ_CP007410.1\|WP_025212608.1\|1960983_1961667_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226647
NZ_CP007410.1\|WP_025212605.1\|1957617_1957926_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007410.1\|WP_025212596.1\|1947659_1948697_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|132866
NZ_CP007410.1\|WP_003183788.1\|1962339_1962633_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007410.1\|WP_025212609.1\|1961677_1962283_+\|arylesterase	unknown	unknown	gnl\|CDD\|238860
NZ_CP007410.1\|WP_025212601.1\|1951606_1953088_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP007410.1\|WP_025212598.1\|1949304_1950066_+\|CHAD-domain-containing-protein	unknown	unknown	gnl\|CDD\|214880
NZ_CP007410.1\|WP_003183777.1\|1965217_1966294_-\|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl\|CDD\|237190

Protein	Function_ID	Function_description	E-value
NZ_CP007410.1\|WP_025212602.1\|1953295_1954105_-\|preprotein-translocase-subunit-TatD	gnl\|CDD\|182449	PRK10425, PRK10425, 3'-5' ssDNA/RNA exonuclease TatD.	6.04947e-108
NZ_CP007410.1\|WP_025212604.1\|1955858_1956293_+\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	8.05549e-20
NZ_CP007410.1\|WP_025212607.1\|1958479_1960984_-\|ABC-transporter-permease	gnl\|CDD\|225669	COG3127, COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP007410.1\|WP_025212610.1\|1962868_1963840_+\|L,D-transpeptidase-family-protein	gnl\|CDD\|182341	PRK10260, PRK10260, L,D-transpeptidase; Provisional.	1.99012e-68
NZ_CP007410.1\|WP_025212599.1\|1950297_1951095_+\|thioesterase-family-protein	gnl\|CDD\|379298	pfam13622, 4HBT_3, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	1.44496e-54
NZ_CP007410.1\|WP_025212603.1\|1954339_1955761_+\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|226971	COG4623, COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein [Cell envelope biogenesis, outer membrane].	2.96711e-121
NZ_CP007410.1\|WP_025212606.1\|1957947_1958445_-\|transcription-elongation-factor-GreB	gnl\|CDD\|179345	PRK01885, greB, transcription elongation factor GreB; Reviewed.	2.95924e-94
NZ_CP007410.1\|WP_025212595.1\|1946785_1947484_+\|response-regulator	gnl\|CDD\|182522	PRK10529, PRK10529, DNA-binding transcriptional activator KdpE; Provisional.	7.60793e-86
NZ_CP007410.1\|WP_025212594.1\|1944085_1946737_+\|sensor-histidine-kinase-KdpD	gnl\|CDD\|225115	COG2205, KdpD, Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms].	0
NZ_CP007410.1\|WP_003183779.1\|1964849_1965131_+\|N-acetyltransferase	gnl\|CDD\|379642	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase. This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule.	4.61152e-26
NZ_CP007410.1\|WP_025212608.1\|1960983_1961667_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226647	COG4181, COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism].	2.66301e-117
NZ_CP007410.1\|WP_025212601.1\|1951606_1953088_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.28719e-71
NZ_CP007410.1\|WP_025212596.1\|1947659_1948697_-\|alpha/beta-hydrolase	gnl\|CDD\|132866	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6. Bacterial patatin-like phospholipase domain containing protein 6. PNPLA6 is commonly known as Neuropathy Target Esterase (NTE). NTE has at least two functional domains: the N-terminal domain putatively regulatory domain and the C-terminal catalytic domain which shows esterase activity. NTE shows phospholipase activity for lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). Exposure of NTE to organophosphates leads to organophosphate-induced delayed neurotoxicity (OPIDN). OPIDN is a progressive neurological condition that is characterized by weakness, paralysis, pain, and paresthesia. This group includes YCHK and rssA from Escherichia coli as well as Ylbk from Bacillus amyloliquefaciens.	4.92049e-73
NZ_CP007410.1\|WP_025212609.1\|1961677_1962283_+\|arylesterase	gnl\|CDD\|238860	cd01822, Lysophospholipase_L1_like, Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity.	9.08729e-96
NZ_CP007410.1\|WP_025212598.1\|1949304_1950066_+\|CHAD-domain-containing-protein	gnl\|CDD\|214880	smart00880, CHAD, The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family. It has conserved histidines that may chelate metals.	5.17566e-30
NZ_CP007410.1\|WP_003183777.1\|1965217_1966294_-\|3-deoxy-7-phosphoheptulonate-synthase	gnl\|CDD\|237190	PRK12755, PRK12755, phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional.	0

>NZ_CP007410.1|WP_025212604.1|1955858_1956293_+|DoxX-family-protein
MSSLINKVLFTRAGYGLTVLRIAVGIIFAAHGSQKLFGLFGGYGLTGTAQWMESIGLTPGYVMATLAGGTEFFAGLALIIGLLARPAALGLAFLSLVAIFSVHIGNGLFMANNGYEFALALLAGSIAVLIEGAGKLSVDRAIAD
>NZ_CP007410.1|WP_025212603.1|1954339_1955761_+|transglycosylase-SLT-domain-containing-protein
MARLQVLLLLCCSLLLPMPAEARLPGPVQAVAPGTVRDLAQIRSSRVLKVLVNQSRNSSGEVQGQPIGVEYHRLRAFEQYLNGHARDGQEITLKIIPKAKDQLLGALQRGEGDLVAPGELLDLQAAHAISASNPIRTDVPLLLVGIKGEKRYTRVEQLSGKTLALPNGSAAGDAVSQINQKLALLKLPPVKIEWVDPSLAVEDVLEMVQGGIFHLTIVEQPIAERWGKILPKLRFDRQVLIGEPSDEYWFVRRDAAMLRASIDQFLAIYKVPSNQDAAFLRIYRRLYQVHYPLARADRQRLEKLRPVLQKHAEAQGMDWLNLAALAFKESALQPNARSGSGPTGLMQITPAAAQRVGVNNIQNLDANVQAGAKYLALIRRKFFASPKLNERERMAFVLAAYNMGPERVQGMRAEARRRGLNPNQWFFQVERIAMEQVGMGAVSYVNSVNKYYLAFDRERESLEPEEQKVAQRK
>NZ_CP007410.1|WP_025212602.1|1953295_1954105_-|preprotein-translocase-subunit-TatD
MQLIDIGVNLTNSSFADKHQAVLERAYEAGVCQLVLTGTSIESSEQALALCERLDDGAERLFSTAGIHPHSASDWTADSARHLKDLLRQSRVCAVGECGLDFNRDFSPRPQQEKVLEEHLALAVELQLPVFLHERDADQRLLEILRDFRDQLPAAVVHCFTGEKKALFSYLDLDLHIGITGWICDERRGTHLHPLVREIPRGRLMLESDAPYLLPRTLRPKPKNGRNEPAYLPEVLREVALHRGETQEDLAAHSTACARAFFGLPSLSE
>NZ_CP007410.1|WP_025212601.1|1951606_1953088_-|methyl-accepting-chemotaxis-protein
MGAWLSNISLKYKFWAVNAVAFVTTLLLVLFAVQLEQQARNHAAQANAQAQARLLEAWPAGQPLPKADHLLGFHREQIPAFNNQALPSLAHADGWVELNAKPLLGDDPLLGAEVIRRGDDQRLAVLAHGASLGQVFGERFSQYAMAVFVLMLAMLGASQLLIRFLLSQLNTLKDVMLHVEKTGDLSARVPLACRDEVGQMAAAFNAMQAGYQRVVDTVATTARQLDSGAARLASSMNDVRRGMLGQQSETDQAATAINEMSATVYHIAQHAGATRDLSKTADTLAGNGREVVSRVQQSITGLSSGVQQTAEMIGRLAEDSQKINGVVSVIHSIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRNLAKRVQSSTDEITTMIAALQAGTRDAVDFMQESSNKADDCVQQAREAGEALEQITGAVAQMRESNTQIAVAAEQQSQVAEEMNRAVVSIRDVTENTVRQTVDSATTSHELATLAGELSKAIGQLKL
>NZ_CP007410.1|WP_025212599.1|1950297_1951095_+|thioesterase-family-protein
MRFSDLIDAVRRQPGAVTIAPEWGQGRASFGGLVAALQYEAMRAQVPADRPVRSLAITFVGPVEADVPVSFEVDVLREGKAVSQVLGRAVQNGQVVTVVQGSFGASRSSVVAVQADPAPEFKSVEQCQELPYIKGGTPEFMRHLAMCWSVGGLPFSGNKSRSMGGWVRLRGDVKEEALNEGHILALVDAWPPALLPHLTQMAPGSTLTWTIEFVQPLLELTTLDWCKYLAEIDHAQDGYGHVAAKFWSADGRLIAISRQTVTIFG
>NZ_CP007410.1|WP_025212598.1|1949304_1950066_+|CHAD-domain-containing-protein
MIDRLVARILGLEVRLLACQARLNAHTDSEALHDLRTTVRRLRSLLRPLRGLPGVEQLETAASAVGTLTTPLRDREVLAAYLEQHGKVEAAKRRQVQMVAAYPAVAGSPELAQLLMIVDAFPRFVRAAQRQGLLKGLRRRIEKRLDKQWKKLGEALRDPAHDRHRLRLLIKRVRYAIEAYPELDRLPEATMPRLKSAQGTLGDWHDCWQWLARAEEEPDLQSCVPTWQDTMAKAEAKSDKVLDKLVASCFKKS
>NZ_CP007410.1|WP_025212597.1|1948906_1949197_+|hypothetical-protein
MKARICLPLVASLMVLALAGCAGKTAYRDNCASQLDSAWRELDLAKAEGFAGTVSYSKALSLLTGAKTQQQFEAFEGCSKKAEKARFYIRESRAGR
>NZ_CP007410.1|WP_025212596.1|1947659_1948697_-|alpha/beta-hydrolase
MTKRVALVLGSGGARGYAHIGVIEEIERRGYDIACIAGCSMGAVVGGIYAAGKLKDYRNWIESLDYLDVLRLVDVSFRLGAIRGEKVFGQIHKIVGDINIEDLRIPYTAVATDLTNQQEIWFQEGCLHQAMRASAAIPSLFTPVMQGNRMLVDGGLLNPLPIVPVVSSHCDLIIAVNLNATNQKQYRLPVIQRPAAFRRRFDTLVNSLGSRLPFRRKQAEQLLLLEQEALKAEAGEINPWLESAEPEGQQPAAAPEAEGAPKSATGSFIIDNVGPASLLDLINQSFEVMQTSLAQYKIAGYPPDVLINVPKRVCRFFEFYKAPELIALGREIARDTLDRYESEKN
>NZ_CP007410.1|WP_025212595.1|1946785_1947484_+|response-regulator
MSQTATLLVIDDEPQIRKFLRISLTSQGYKVLEAGTGTEGLALAALNKPDLLVLDLGLPDMDGQQVLREFRQWSTVPVLVLSVRASEAQKVEALDNGANDYVTKPFGIQEFLARIRALLRQAPAGEAQEAALRFGPLTVDLAYRRVLLDGAEVALTRKEYAVLAQLARHPGRVITQQQLLKDIWGPTHTEDTHYLRIVVGHLRQKLADDPTRPRFIATEAGVGYRLLEEGSA
>NZ_CP007410.1|WP_025212594.1|1944085_1946737_+|sensor-histidine-kinase-KdpD
MSDSGRADALLANLPRNDRGRLKVFLGAAPGVGKTYAMLQAAHTQLRQGVKVVAGVVETHGRAETEALLGGLAQQPLVRSEYRGVMLEEMDLDGLLAARPSLVLVDELAHSNAPGSRHAKRWQDIQELLAAGIDVYTTVNVQHLESLNDQVRGITGVQVRETLPDWVLQEADELLLIDLPPRELLERLRDGKVYVPEQARAAIDAFFTQTNLTALRELAMQTAAAQVDNDLTQGYRQLGQAAPAVRGRLLVGVDGDVQAERLVRHASRVAQRRHLPWSLVHVDNGSARDESSRQRLQNAQLLAERLGGEVVLLRAGEVARTLIQHATERRATLVLVGQSRPRLRRRLFGGGLASRLLRDARGLEINVLDSDEQPRPAHVRSSTVQTGFDYALALLATVAASALAWGISGLLALPNISLVFLMAVLLVAVRSSLGPALACAAMSFLAYDFLFIPPNFSLTIQREEDVLTLVFFLLMAALTGNLAARQRRQLQALRDTQQETGELLDLSRKLTAATDRQAVVSAAAQHLNGLHDLQLCLLNRDGQGDWKIETGEPLTFTEAERAAADWAWQHDQPAGAGTGTLPSGRWWWWPLSAEGGPLALLGVCPKEGKPLSGQRRRLLAALSQPLAQALARAQLAQDLEAARLHGETEQLRSALLASVSHDLRTPLTSMRGSIDSLLALGEAIPLADRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLARDWVAPADIVCSALNRLRAVLAPLAVGIEVPADLPLLYVHAALIEQALINVLENAARFSPVNGRLLLSAGMTGNEVFFAVADEGPGIPQQEREKIFDMFYTAARGDRGGQGTGLGLAICQGMVGAHGGRISVADGLDGHGTCITLHLPLQAQPDMDDEA
>NZ_CP007410.1|WP_025212605.1|1957617_1957926_+|hypothetical-protein
MNASSPLVRLAPITANLLQRNPKILLGGTHQPTLLRYLDGWPRRSHGPAAFLIQFVEDGESLARFANDSFDLAVIQSPSAADAPEMIRQLTRVARQGLITRR
>NZ_CP007410.1|WP_025212606.1|1957947_1958445_-|transcription-elongation-factor-GreB
MSRYRPPRTAGTALITPEGEARMRAEFHELWHVRRPQVTQSVSEAAAQGDRSENAEYTYGKKMLREIDSRVRFLTKRLEALKVVSEKPSDPNKVYFGAWVTVEDEDGKEARYRIVGPDELDLKQNLISIDSPLARALIGKALDAEVSVQTPTGEKRVYIVDIVYP
>NZ_CP007410.1|WP_025212607.1|1958479_1960984_-|ABC-transporter-permease
MARLPLLRLFSLAVRQLLRDARAGELRVLFFALLVAVAASTAIGYFGARLNGAMMMRATEFLGADLLLEGSSPARPEQIRSGTELGLEHARVVEFSSVVATDNGIQLSSVKAADDIYPLRGELKSAPAPFAPEETGGRPNPGEAWVEARLLTALDLKIGDSIDVGNKTLRLSRVLTYEPDRAGNFYSLTPRVLINLKDLDATGVVQPGSRVSYRDLWRGPASALQTYRDLIKPGLEANQRLQDARDGNRQIGGALGKAERYLNMASLVAVLLSGVAVALSANRFATRRFDASALLRCLGLSRRETMVLFSLQLTVLGLLASISGALLGWIAQLGLFALLHDLLPTTVPPGGLLPAIAGIGTGLVALAGFALPPLAALGRVPPLRVLRRDMLPIPSSTWVVYGAALGALGLIMWRLSLDLVLTFALLGGGVVAALVLGGLLLLLLQSLRRLLARASLPWRLGLGQLLRHPLAAAGQALAFGLILLSMALIALLRGELLDTWQNQLPKNAPNYFALNILPNDKQAFTDKLLALSAQSAPLYPVVPGRLISINGEPATEFVTKDSAGDRALQRDLSLTWAADLPAGNIVTAGTWWSQQPPDDVPGVSVEGKVADNLKIKLGDRLIFSVGGVNREAKVTSLREINWDNFQPNFFMIFQPGTLKDLPATYLTSFYLAAGHDQQIVDLSRSFPAVTILQVEALLEQLRSILAQVTLAVEYVLLFVLAAGMAVLFSGLQATLDERIRQGALLRALGAERPLLVKARRIEFGLLGAVSGLLAALGSELVSLVLYRYAFDLPWHPHPWLLVLPLVGALLIGTAGVFGTRRALNASPLTVLREG
>NZ_CP007410.1|WP_025212608.1|1960983_1961667_-|ABC-transporter-ATP-binding-protein
MGSSILTAKDLSKVVPSAEGELTILHELSLELNKGDSLAIVGASGSGKSTLLGLLAGLDLPSSGEVTLAGQALSLLDEDQRARIRAEHVGFVFQSFQLLDSLNALENVMLPLELDGRKDARERATELLQRVGLGQRLTHSPRQLSGGEQQRVAIARAFAAEPDVLFADEPTGNLDSHTGERISDLLFELNKESGTTLVLVTHDERLAHRCRRLIRLEAGQMVAPLEP
>NZ_CP007410.1|WP_025212609.1|1961677_1962283_+|arylesterase
MRVWFLSAGLALMCMAQNAAAGTVLIVGDSISAAFGLDTRQGWVALLEQRLKAEGFDDKVINASISGDTSSGGQARLPALLAAHKPDLVILELGGNDGLRGQPPTQLQQNLAVMIDSSRASGAKVLLLGMQLPPNYGRRYTDAFARVYSTLAEEKKVPLVPFFLKDIGGVPGMMQGDGLHPSVAAQGKLLENVWPTLKPLL
>NZ_CP007410.1|WP_003183788.1|1962339_1962633_+|hypothetical-protein
MPRPAWSLFAYQLIEPDEQLDLFACQEVRVHLVTRQLELGGSADRTLCGSLLPAQPRWSGVDRKIFQDHRLCSLCRAILESQKRGTSPIWPELRFEL
>NZ_CP007410.1|WP_025212610.1|1962868_1963840_+|L,D-transpeptidase-family-protein
MLPRLPAVTRCLSLAALCMAGPVAALELPLPPPGEDIIGQVQVIKAKYEDTFADLGTTYDLGYTEMVAANPGVDPWLPGAGTEIVLPTRFILPPGPREGIVINLAEYRLYYFPKGRNVVYTFPLGIGREGWGSPIAHTSIIAKTPNPTWTPPASIKAEHAADGDPLPNVVPAGPDNPLGPFKFTLGTPGYLIHGSNKKFGIGMRTSHGCFRMFNNNVLEMAGMVPVGTSVRIINDPYKLGLSGGKVYLEAHTPLDDKGNPSVVDKHTAVINAMLKREDITSNQRMDWNVVRDVVAAEDGLPVEIAVPSTSAPMVSSAPIDLQQ
>NZ_CP007410.1|WP_003199355.1|1963963_1964215_-|hypothetical-protein
MNNVLKFSALALAAVLATGCSSASKETEARLTATEDAAARSQARADEAYRKADEALAAAQKAQQTADEANERALRMLDKASRK
>NZ_CP007410.1|WP_003183779.1|1964849_1965131_+|N-acetyltransferase
MSEALSIHHDQAGHQFETNVDGHRAYLTYMDLGKQTLDIYRTFVPNALRGRGIAAALTERALQYAEEMGYTVIPSCSYVERYMERHQRHAAKL
>NZ_CP007410.1|WP_003183777.1|1965217_1966294_-|3-deoxy-7-phosphoheptulonate-synthase
MADLPINDLNVASNETLITPDQLKRDIPLSDAALRTVTKGREVIRNILDGTDHRLFVVIGPCSIHDIKAAHEYAERLKVLAAEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDDSFKIQDGLHIGRQLLLDLAEMGLPTATEALDPISPQYLQDLISWSAIGARTTESQTHREMASGLSSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRGGNGKPNYDSVSVALCEQALNKAKIKPNIMVDCSHANSNKDPALQPLVMENVANQILEGNQSIIGLMVESHLNWGCQAIPKDLADLQYGVSITDACIDWSATENTLRSMHAKLKDVLPKRQRS

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Crispr_ID: NZ_CP007410_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007410_2

3933580-3933667

Orphan

Consensus_repeat	Method
AAATGCGGTGAAGGCAAGTGTGGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007410_2

>merge|NZ_CP007410|2|3933580-3933667|CRISPRCasFinder
AAATGCGGTGAAGGCAAGTGTGGCGCGGCCAACACGACCAACAAAGTCAGCCAGTCGGAAGGTAAATGCGGTGAAGGCAAATGTGGCG

>NZ_CP007410|2|2|3933580-3933667|CRISPRCasFinder
AAATGCGGTGAAGGCAAGTGTGGCG	CGGCCAACACGACCAACAAAGTCAGCCAGTCGGAAGGT
AAATGCGGTGAAGGCAAATGTGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007410.1\|WP_025214112.1\|3928866_3929742_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP007410.1\|WP_025214114.1\|3930639_3931230_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP007410.1\|WP_025214123.1\|3936841_3938050_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_CP007410.1\|WP_025214128.1\|3942253_3942868_-\|urea-carboxylase-associated-family-protein	unknown	unknown	gnl\|CDD\|378156
NZ_CP007410.1\|WP_025214113.1\|3929850_3930564_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|183714
NZ_CP007410.1\|WP_025214122.1\|3936204_3936831_+\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238245
NZ_CP007410.1\|WP_025214119.1\|3933955_3934819_+\|DUF692-domain-containing-protein	unknown	unknown	gnl\|CDD\|235447
NZ_CP007410.1\|WP_025214110.1\|3925716_3927483_+\|S8/S53-family-peptidase	unknown	unknown	gnl\|CDD\|173787
NZ_CP007410.1\|WP_025214109.1\|3925372_3925609_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007410.1\|WP_025214117.1\|3932572_3933091_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007410.1\|WP_025214125.1\|3938783_3940214_-\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP007410.1\|WP_025214120.1\|3934799_3935540_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225760
NZ_CP007410.1\|WP_025214126.1\|3940546_3941215_+\|FMN-dependent-NADH-azoreductase	unknown	unknown	gnl\|CDD\|224103
NZ_CP007410.1\|WP_025214111.1\|3927852_3928722_-\|NmrA/HSCARG-family-protein	unknown	unknown	gnl\|CDD\|187561
NZ_CP007410.1\|WP_038436656.1\|3938185_3938737_-\|methylmalonyl-CoA-epimerase	unknown	unknown	gnl\|CDD\|319912
NZ_CP007410.1\|WP_025214116.1\|3931727_3932462_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP007410.1\|WP_080712569.1\|3927540_3927702_+\|DUF2986-domain-containing-protein	unknown	unknown	gnl\|CDD\|314517
NZ_CP007410.1\|WP_025214115.1\|3931247_3931619_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP007410.1\|WP_025214121.1\|3935552_3936050_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP007410.1\|WP_025214127.1\|3941223_3942165_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990

Protein	Function_ID	Function_description	E-value
NZ_CP007410.1\|WP_025214112.1\|3928866_3929742_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.4856e-50
NZ_CP007410.1\|WP_025214114.1\|3930639_3931230_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.65713e-08
NZ_CP007410.1\|WP_025214123.1\|3936841_3938050_+\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.32848e-59
NZ_CP007410.1\|WP_025214128.1\|3942253_3942868_-\|urea-carboxylase-associated-family-protein	gnl\|CDD\|378156	pfam09347, DUF1989, Domain of unknown function (DUF1989). This family of proteins are functionally uncharacterized.	8.03885e-63
NZ_CP007410.1\|WP_025214113.1\|3929850_3930564_-\|SDR-family-oxidoreductase	gnl\|CDD\|183714	PRK12742, PRK12742, SDR family oxidoreductase.	1.05925e-151
NZ_CP007410.1\|WP_025214122.1\|3936204_3936831_+\|cysteine-hydrolase	gnl\|CDD\|238245	cd00431, cysteine_hydrolases, Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It also contains isochorismatase, an enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond, and other related enzymes with unknown function.	1.03886e-42
NZ_CP007410.1\|WP_025214110.1\|3925716_3927483_+\|S8/S53-family-peptidase	gnl\|CDD\|173787	cd00306, Peptidases_S8_S53, Peptidase domain in the S8 and S53 families. Members of the peptidases S8 (subtilisin and kexin) and S53 (sedolisin) family include endopeptidases and exopeptidases. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. Serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of subtilisin. The serine residue here is the nucleophilic equivalent of the serine residue in the S8 family, while glutamic acid has the same role here as the histidine base. However, the aspartic acid residue that acts as an electrophile is quite different. In S53, it follows glutamic acid, while in S8 it precedes histidine. The stability of these enzymes may be enhanced by calcium; some members have been shown to bind up to 4 ions via binding sites with different affinity. There is a great diversity in the characteristics of their members: some contain disulfide bonds, some are intracellular while others are extracellular, some function at extreme temperatures, and others at high or low pH values.	1.17717e-24
NZ_CP007410.1\|WP_025214119.1\|3933955_3934819_+\|DUF692-domain-containing-protein	gnl\|CDD\|235447	PRK05409, PRK05409, hypothetical protein; Provisional.	1.40447e-144
NZ_CP007410.1\|WP_025214125.1\|3938783_3940214_-\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	3.05391e-77
NZ_CP007410.1\|WP_025214120.1\|3934799_3935540_+\|hypothetical-protein	gnl\|CDD\|225760	COG3219, COG3219, Uncharacterized protein conserved in bacteria [Function unknown].	2.18645e-52
NZ_CP007410.1\|WP_025214126.1\|3940546_3941215_+\|FMN-dependent-NADH-azoreductase	gnl\|CDD\|224103	COG1182, AcpD, Acyl carrier protein phosphodiesterase [Lipid metabolism].	1.14115e-47
NZ_CP007410.1\|WP_025214111.1\|3927852_3928722_-\|NmrA/HSCARG-family-protein	gnl\|CDD\|187561	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs. NmrA and HSCARG like proteins. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	8.25632e-60
NZ_CP007410.1\|WP_038436656.1\|3938185_3938737_-\|methylmalonyl-CoA-epimerase	gnl\|CDD\|319912	cd07249, MMCE, Methylmalonyl-CoA epimerase (MMCE). MMCE, also called methylmalonyl-CoA racemase (EC 5.1.99.1) interconverts (2R)-methylmalonyl-CoA and (2S)-methylmalonyl-CoA. MMCE has been found in bacteria, archaea, and in animals. In eukaryotes, MMCE is an essential enzyme in a pathway that converts propionyl-CoA to succinyl-CoA, and is important in the breakdown of odd-chain length fatty acids, branched-chain amino acids, and other metabolites. In bacteria, MMCE participates in the reverse pathway for propionate fermentation, glyoxylate regeneration, and the biosynthesis of polyketide antibiotics. MMCE is closely related to glyoxalase I and type I extradiol dioxygenases.	1.18688e-17
NZ_CP007410.1\|WP_025214116.1\|3931727_3932462_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	7.92471e-70
NZ_CP007410.1\|WP_080712569.1\|3927540_3927702_+\|DUF2986-domain-containing-protein	gnl\|CDD\|314517	pfam11661, DUF2986, Protein of unknown function (DUF2986). This family of proteins has no known function.	2.52134e-05
NZ_CP007410.1\|WP_025214115.1\|3931247_3931619_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.31934e-36
NZ_CP007410.1\|WP_025214121.1\|3935552_3936050_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	2.07407e-37
NZ_CP007410.1\|WP_025214127.1\|3941223_3942165_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	7.89471e-62

>NZ_CP007410.1|WP_025214117.1|3932572_3933091_-|hypothetical-protein
MNLRLLAASLFLTSTLSHAAEPAPIPKVLEQQIERLVALVKDSYATGYPEATLTQTLDTGEDSQVTLAVFTVEGFGMGNNYSQYLAAFTPEESEDGASHYSLLDVVRIGGDSWRAIDKLDAKLVSDPAGERILIDLPVMENTDDDAPNFPSKAAVIHLSLEGSNSLRLVEIK
>NZ_CP007410.1|WP_025214116.1|3931727_3932462_+|SDR-family-oxidoreductase
MTRLNGKTAVITGGATGIGLAAAKRFIEEGAFVFIFGRRQEALDAAVADLGPKARAVKGSVSNLADLDRLYTAVKAERGSLDIVFANAGAGSPLALGEITAEHIDETFETNVKGTIFTVQKALPLMGQGGSIILTGSSAGATGAPAFSVYSASKAAVRNLARTWAQDLQGTGIRVNVLSPGPTATELAKTALGEEGMKVFASMNPLQRMADPAEIGAVAAFLASQDSSFMTASEVAADGGLAQI
>NZ_CP007410.1|WP_025214115.1|3931247_3931619_-|helix-turn-helix-transcriptional-regulator
MTTPIQTCGTGGFSCGLDATLRIISGKWKPLVLFFLRDGPKRYGELKRLVQGVSDKVLIQALKDLEADHVLARTDYKEVPPRVDYTLTPLGHSLAEAIVPLCTWGTEHMAEMANIFAKRDTLS
>NZ_CP007410.1|WP_025214114.1|3930639_3931230_+|TetR/AcrR-family-transcriptional-regulator
MTTNTLPTRGRPRRFDPDEAVATAQHLFHAKGYDGVSVADLTKALGINPPSFYAAFGSKAQLYARVLDRYALTGAVPLSQILAADQPLAVSLAQVLEQAARSYAADPMATGCMVLEGTRCNDSQARDAACGFHVAAQDLIRNSIAERYPQEAARLADFVSTTMAGLSASARHGQGLDRLLATAGLAGMAIAQVLAA
>NZ_CP007410.1|WP_025214113.1|3929850_3930564_-|SDR-family-oxidoreductase
MSDFKGKSVLVLGGSRGIGAAIVRRFASEGANVAFTYSGSPEAAKLLATETGSSAYSTDSADRDAVIARVRESGPLDVLVVNSGIAIFGDALEQDPDAIDRLLRINVHAPYHASVEAARQMPEGGRIIVIGSVNGDRMPVPGMASYALSKSALQGMARGLARDFGPRGITINIVQPGPIDTDANPEDGPMKDLMHSFMAIKRHGRPEEVAAMVAWLAGPEASFVTGAMHTIDGAFGA
>NZ_CP007410.1|WP_025214112.1|3928866_3929742_+|LysR-family-transcriptional-regulator
MNLNALIDFILVATNEGLGKASRASGISKATLSRRISDLEEQLGVRLIERSARGLKLTEAGERLMSRTEGPLSEVTEAMTAVREGVSIPRGRLRVAAPVLFSQLAMGRIGAEFCRAYPEVEIEVVAEDRQVDLVEEQFDVAIRINPSPDSNLVGRCFAKDRLVVVAAPEVSKPVPGAIRAVPAIVTSTFQPTQWSLDGGQLVLEPIPKLRFSSLLMVRDAAITGGGVALIPQSIAWNQLARGELVQWGTVLGIEPQLWVLHTSRRLAAPKVRAFVDFICAQYPDMSLVLKG
>NZ_CP007410.1|WP_025214111.1|3927852_3928722_-|NmrA/HSCARG-family-protein
MSILVIGATGTIGSLVTQGLADAGAEVKALVRQPGKRTFPAGVTEVVADLTDVPSIRVALSSVRTLFLLNAVVPDEVTQALIALNLAREAGIERIVYLSVIHADKFTNVPHFTGKHTVERMIESLDMPATILRPAYFMQNERMVQQTIQDYSVYPMPIGSAGTSMIDARDIADVAVAELLRRDKAPSALDRVTLELVGPQALTGASVAQIWSAALGREIAYGGDDVTAFEGQMAAYGPAWLAYDMRLMMAGIQAFGMQAAEGAVGRLEAIIGHPLRTYEDFVREAIAGV
>NZ_CP007410.1|WP_080712569.1|3927540_3927702_+|DUF2986-domain-containing-protein
MNRRKKINQLLKANAKKASAKLAPKNKSKYISKADRLKLAAESSDDSMVSAES
>NZ_CP007410.1|WP_025214110.1|3925716_3927483_+|S8/S53-family-peptidase
MPLRSAVLATLFTLAANTAAAAPGPLRLENLARCGDLLDGRRQDWCLTVRGLGEGTPQLKLGDKTIPASTVQREGDKLRLRLDSAEYQSGPLWLEDGPRTSNAAWLTLRNSHVLAAGPDDVAKNMDGLSTYVDLVSVLIEEDRDGPQEAERLASKYGAKVVGSIAPLNLYQLRLPARDLVQRDALVLRLGSETGVDAVVVEESAAEESEQAPVRPEEPKKPDPDSDEWAANRFLDAVHYYQRRIPGQQAPSRPQPVRVGLIERDVDFDTADFADYLGACSMPRTCVYARDADKPDNHGTTVAGILAARWNDGGNTGFLRGLDKASGGFEVIVDRNSDAGITANIAASVNLVEDGVRVLNWSWGIHRVGAKDIKGDDVDSLLRSGIAMGGYEELLEEFFLWLRKEHPDVVVVNSAGNGSSFSGTDEYRLPSSFITEQLLVVGGHQRNERAGVAIDDPAYARKRSSSNIDMRVDITAAACTHASTTDAGQDGAVHCGTSYATPMVAGLLAAMLSINPQLQPEQLRMLLRRSAMTIGDNHDFEQMDAEDLTAPILPSERRYQLNDKDVGRSARLDMQKALDLAEQSRKRVR
>NZ_CP007410.1|WP_025214109.1|3925372_3925609_+|hypothetical-protein
MRTFDLIRDAVLPDFRDRVAEYLIQYETVLLSENATDPELIRDTAHQLRGYLRGLNTTRVLGMADWEELDRRVVNTWL
>NZ_CP007410.1|WP_025214119.1|3933955_3934819_+|DUF692-domain-containing-protein
MTILVPPTNAGLGLRRAMLGDLMTMDADAVDFLECAPDNWIGVGGAYVQQLDRLAERYPLTCHGLSLSLGGAQPLDLDLLRGTREFLNRYAVTIYSEHLSYCADQGHLYDLLPIPFTEEAVHHVAARIRQAQDVLGQRIAVENISYYAAPFQAMSEIEFIRAVLDEADCDLLLDVNNLYVNAINHGYDASQFLAAVPTQRVTYLHVAGHYDEADDLKIDTHGASVKQDVWALLHQAYQRLGPVPTLLERDFNFPPLPQLLAEVDQIKHLQRLGLPTGLEAQHVRTIA
>NZ_CP007410.1|WP_025214120.1|3934799_3935540_+|hypothetical-protein
MSERLLEQLSCMADYVRDPRRPGPPGVQTRRLAVYRQLFLGNIDSLLAGSFPVIRRTLATADWQRLVNDFYAGHRCRTPLFTEIAGEFVSYLEQRADSHGFPAWLVELAHHEWSESALLLSDAKDPAHDPRGDLIQGTPVVSAQAWTRAYLWSVCDIGPGHQPVEPPPAPTLLLLRRHEGQVTFSRLAPLAYSLLVSLTEFPRSGHEHLIALAETAGVPAQELLPAGVAALNDFRAQGIVLGTGTD
>NZ_CP007410.1|WP_025214121.1|3935552_3936050_-|helix-turn-helix-transcriptional-regulator
MRDETSETMCPVARSVDVVGDKWTTLVLRELYLGTTRFEEIQIQTGATPQMLTSRLKALEADGMVERRPYSERPLRYEYHLTDKGWDFYPVIYALRAWGEKWCKHEDDGLAMHFVHRACGHDVGVASVCPNCGVAVERKDLQASISERFLDERTARREAYKRKPS
>NZ_CP007410.1|WP_025214122.1|3936204_3936831_+|cysteine-hydrolase
MTQPVYSPTRTGLLLVDPYNDFLSNGGKLFPLLENVAQDVHLLDNLRASVAAARQQGVQVFYVPHRRWQPGDYDNWQHPNPTQRLIQQRHTFAKGTWGGEWHPDFVPEDGDIIIQEHWGQSGFANTDLDFQLKQQGITHVIVVGLLANTCIESTARFAMELGYHVTLVRDATAAFSAEMMHAAHELNGPTFAHSIVDTRTLTLALQQH
>NZ_CP007410.1|WP_025214123.1|3936841_3938050_+|MFS-transporter
MSSIPAVSNTIPARLVVVMAVCCALAVAAIYYHQPLLPLMAASFGLTPTQAGLIATLTQLGYGIGLLLIVPLADCRQPRRLALWAIGANTAALLACAAAPSFALLCASSLVVGVTAVTAQLIIPALSGLAAPVERGRVVGTLLSGLSAGLLLARTVGGVVGEHAGWRAVFLMASLVDGLLLVIVAKNLPAMPRVASIRYGELMRSLGSLLREERVLRFSAASGFLIFAAFSSLWATLAALLTQPPYGFGSTTIGLFGLVTVLGIVASPRIGALADRLGARTVALAGAIFLAVGFACIAAGGRSLGWLIIGMVLLDLGNRTGLVANQARIHTLRPEARSRLNTVFMGSYFLGGAVGAALGNYGVHRAGWIGLAAVGALLAVAATTISALSPRDSRVTLMDACP
>NZ_CP007410.1|WP_038436656.1|3938185_3938737_-|methylmalonyl-CoA-epimerase
MSHLEQTNVLAALNAGVEIDAFLGNVVEIAIVTRDHKRTMDGLLKLGIGPWRVYTFSPENTQDQTYHGEPAEFVLKVCFAQSGNMIWELMEPVSGPTIFADFLDKHGEGIQHVAYDCNNIPFEDRIAELQRRGFKCVQSGSWMGVNHFAFFGTEADTTTVFETYAFPADWDYPEPESWYPPRA
>NZ_CP007410.1|WP_025214125.1|3938783_3940214_-|cytosine-permease
MSTRRESENSLMNEANYDALGLEPVPDCQRTSTPLDQFWIWAGANVAPINWVLGAIGIQLGLSLIETLLVIVVGNLLGAALFGGICIMGHRTGVPQMVLSRLAFGRRGAYLPTLMQVLMPMGWVATNTWVVLDLAVAALERVGINGGMELKYAIALAVMVLQVGIAAWGFNAIKCFERYTMPVILLIMVVMTGLAFTHVDIQWQTSTVAGIGKLSAMSSLMTAIGIGWGISWLVYASDYTRFTQAKLSDGQVFRSTFLGMFLPTVWLAFLGAAIASAGAGSDPAQLIIAVFGTMALPVLLVLLHGPVATNIVVIYSAALATLSLDLRLPRWAVSTISGVVALFLLYLFLQSGEFVHAFENLMVFFVVWISPWAGITLVDFFLIRRGQVDLKSLYCHHLESACTDVNWKGVFALAAGVLAAWLFQVGTIKSLQGPLAMALGGIDLSWLAGFGVGGGIYYVLHRSRRIEVVHSTVMVK
>NZ_CP007410.1|WP_025214126.1|3940546_3941215_+|FMN-dependent-NADH-azoreductase
MTTLLHIDASARSDRSLSRKLSQAFVEAWLERDGKTQIIARDVGHNPPPFVTEAWIAAVFTPEEHLTPEKREEIRLSDELIDEIDRADVIVIGTPMYNYGMPAALKSWFDKVIRIGKTFTFDLARGDYPLEPIMSGKKLVILSSRGEFGFGPGGVRETMNHLDTHIQTCAHYLGVNETHVISIDYQEFGDARHEASIANAFDAVPVLVRQMIEERHSQLSPA
>NZ_CP007410.1|WP_025214127.1|3941223_3942165_-|LysR-family-transcriptional-regulator
MRKIPPLNSVRAFEAVARHQSFSAAANELSVTVAAVSHQVRQLEDGLGQKLLERGRTLTLTPAGKAIYPLLRDGFDQIAQAFALLGGAKEGDAVQVSTTRAFAERWLMPRLAKFNEIYPNIVVSIHASEKVVDLRSDAVDLAIRYGPVDADVQGPVLFEDRFIAVADRRICPVDRNATMSDFHNRPLLAFKWKNQALEAPSWSVWLAGMKHGTTGDLRISWYSEETLALHALERGLGPLLCSDVLIDDELRSGRIRRVEGPTLPGFTYHLIEGHNGSPRRSLALFREWLLGEARSFRGTALNDLAGHQLALTS
>NZ_CP007410.1|WP_025214128.1|3942253_3942868_-|urea-carboxylase-associated-family-protein
MNTMASTCPGERVLLPARRGVAIRLNQGQALQVINTHGKQVVDTWAFNPDDLREAMSMEHSRPYWLKLNPGQGDSFLTNKRRQILTLIEDTTPGVHDTLVAACDPTRYVQLGVVGHHDSCNENLFQALDAIGLVAPETPSPLNLFMNVPVHQDGRIAFAEPVSQPGQYVCLKAEMDAIVVLSACPQDITAVNGMWPQDVHYCIL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1343521 : 1436788

uncultured_Caudovirales_phage(21.05%)

protease,plate,holin,tail,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025212102.1\|1343521_1344340_+\|tRNA	tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA	S4VW33	Pandoravirus	1.6e-09	28.7
WP_025212103.1\|1344466_1344874_-	SufE family protein	NA	NA	NA	NA
WP_025212104.1\|1344870_1346076_-	cysteine desulfurase	Q2XUY6	environmental_halophage	8.1e-71	37.7
WP_025212105.1\|1346202_1347237_-	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	NA	NA	NA	NA
WP_025212106.1\|1347269_1347632_-	ArsC family reductase	NA	NA	NA	NA
WP_025212107.1\|1347933_1349580_+	Na+/H+ antiporter	NA	NA	NA	NA
WP_025212108.1\|1349791_1350400_-	short chain dehydrogenase	NA	NA	NA	NA
WP_025212109.1\|1350508_1351423_+	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.9e-08	27.1
WP_025212110.1\|1352027_1352387_+	hypothetical protein	B5TK57	Pseudomonas_phage	2.4e-23	59.7
WP_025212111.1\|1352637_1353837_-	succinyldiaminopimelate transaminase	NA	NA	NA	NA
WP_025212112.1\|1353974_1356677_-	[protein-PII] uridylyltransferase	NA	NA	NA	NA
WP_025212113.1\|1356721_1357504_-	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_003198231.1\|1357952_1358690_+	30S ribosomal protein S2	NA	NA	NA	NA
WP_025212114.1\|1358881_1359745_+	elongation factor Ts	NA	NA	NA	NA
WP_003184915.1\|1359958_1360702_+	UMP kinase	NA	NA	NA	NA
WP_003198238.1\|1360698_1361256_+	ribosome recycling factor	NA	NA	NA	NA
WP_025212115.1\|1361269_1362025_+	di-trans,poly-cis-decaprenylcistransferase	R9W0U9	Flavobacterium_phage	5.5e-17	37.3
WP_025212116.1\|1362024_1362831_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_025212117.1\|1362827_1364018_+	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_025212118.1\|1364070_1365423_+\|protease	sigma E protease regulator RseP	NA	NA	NA	NA
WP_025212119.1\|1365497_1367885_+	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_003184901.1\|1367930_1368434_+	OmpH family outer membrane protein	NA	NA	NA	NA
WP_025212120.1\|1368437_1369493_+	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	NA	NA	NA	NA
WP_008154051.1\|1369595_1370036_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_025212121.1\|1370032_1370809_+	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase	NA	NA	NA	NA
WP_162178160.1\|1370808_1371942_+	lipid-A-disaccharide synthase	NA	NA	NA	NA
WP_025212123.1\|1371938_1372598_+	ribonuclease HII	V5LS49	Emiliania_huxleyi_virus	6.0e-28	40.1
WP_025212124.1\|1372839_1376361_+	DNA polymerase III subunit alpha	A0A1C9LWZ5	Streptomyces_phage	5.1e-198	36.6
WP_025212125.1\|1376510_1377458_+	acetyl-CoA carboxylase carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_038436466.1\|1377608_1378910_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_025212126.1\|1379208_1380840_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	5.3e-158	53.5
WP_025212127.1\|1380844_1381690_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.4e-48	42.4
WP_025212128.1\|1381894_1383184_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.2e-136	59.4
WP_025212129.1\|1383355_1383634_+	cell division protein FtsB	NA	NA	NA	NA
WP_025212130.1\|1383630_1384338_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_025212131.1\|1384514_1385411_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_025212132.1\|1385519_1386632_+	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	1.2e-33	29.5
WP_025212133.1\|1386640_1387486_+	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_025212134.1\|1387529_1388003_+	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_025212135.1\|1387999_1389058_+\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_025212136.1\|1389045_1389795_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	2.6e-67	52.6
WP_025212137.1\|1389794_1390472_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	8.0e-44	50.0
WP_025212138.1\|1390698_1391547_+	peptidoglycan DD-metalloendopeptidase family protein	A0A0S2SXL7	Bacillus_phage	8.3e-06	33.3
WP_003198289.1\|1391653_1392661_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	6.6e-34	35.8
WP_025212139.1\|1393172_1393496_-	ferredoxin family protein	NA	NA	NA	NA
WP_025212140.1\|1393638_1396218_-	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	2.4e-27	22.1
WP_025212141.1\|1397579_1398314_+	helix-turn-helix transcriptional regulator	B5TK58	Pseudomonas_phage	1.5e-133	97.5
WP_025212142.1\|1398859_1399288_+	hypothetical protein	NA	NA	NA	NA
WP_025212143.1\|1399418_1399769_+\|holin	pyocin R2, holin	B5TK61	Pseudomonas_phage	2.3e-58	95.7
WP_025212144.1\|1399805_1400318_+	hypothetical protein	A0A2H4JEV5	uncultured_Caudovirales_phage	2.5e-21	39.6
WP_025212145.1\|1400321_1400933_+\|plate	phage baseplate assembly protein V	A0A2H4JBW8	uncultured_Caudovirales_phage	1.2e-43	60.4
WP_025212146.1\|1400944_1401277_+\|plate	phage baseplate protein	A0A2H4JI46	uncultured_Caudovirales_phage	1.1e-38	71.8
WP_025212147.1\|1401273_1402269_+\|plate	baseplate J protein	A0A2H4JC04	uncultured_Caudovirales_phage	2.3e-111	64.1
WP_025212148.1\|1402265_1402901_+\|tail	phage tail protein I	A0A2H4JDK0	uncultured_Caudovirales_phage	9.5e-47	56.0
WP_025212149.1\|1402901_1404449_+\|tail	tail protein	A4PE45	Ralstonia_virus	2.2e-57	47.4
WP_025212150.1\|1404530_1404968_+	hypothetical protein	B5TK82	Pseudomonas_phage	6.8e-28	41.4
WP_025212151.1\|1405057_1405267_+	hypothetical protein	NA	NA	NA	NA
WP_025212152.1\|1405269_1406436_+\|tail	tail protein	B0ZSG8	Halomonas_phage	5.5e-125	57.0
WP_025212153.1\|1406435_1406942_+\|tail	phage tail protein	Q6R4W3	Vibrio_virus	2.7e-20	33.9
WP_025212154.1\|1407152_1407728_+\|tail	phage tail assembly protein	B0ZSH0	Halomonas_phage	4.0e-28	38.5
WP_025212155.1\|1407856_1410031_+\|tail	phage tail tape measure protein	A2I2Y1	Vibrio_virus	3.3e-30	34.5
WP_025212156.1\|1410030_1410414_+\|tail	phage tail protein	A0A2H4JAC8	uncultured_Caudovirales_phage	3.1e-32	51.2
WP_025212157.1\|1410406_1410619_+\|tail	tail protein	A0A2H4JGD9	uncultured_Caudovirales_phage	1.5e-17	62.9
WP_025212158.1\|1410628_1411645_+	hypothetical protein	A0A2H4JH05	uncultured_Caudovirales_phage	9.4e-105	55.8
WP_025212159.1\|1411717_1412281_+	glycoside hydrolase family 19 protein	B5TK83	Pseudomonas_phage	4.9e-95	90.9
WP_038436476.1\|1412262_1412799_+	lysozyme	B5TK84	Pseudomonas_phage	7.4e-77	88.2
WP_025212161.1\|1412870_1413371_+	CinA family protein	B5TK85	Pseudomonas_phage	2.0e-84	94.6
WP_003184807.1\|1413454_1414507_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	3.8e-109	61.4
WP_025212162.1\|1414515_1414983_+	recombination regulator RecX	NA	NA	NA	NA
WP_025212163.1\|1415029_1416148_-	TIGR00730 family Rossman fold protein	NA	NA	NA	NA
WP_025212164.1\|1416603_1416798_+	hypothetical protein	NA	NA	NA	NA
WP_025212165.1\|1416798_1417221_-	quorum-sensing-regulated virulence factor family protein	NA	NA	NA	NA
WP_025212166.1\|1417405_1418152_+	DTW domain-containing protein	NA	NA	NA	NA
WP_025212167.1\|1418366_1419020_+	response regulator transcription factor	NA	NA	NA	NA
WP_025212168.1\|1419092_1419455_+	diacylglycerol kinase	NA	NA	NA	NA
WP_025212169.1\|1419467_1420394_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003198368.1\|1420515_1421295_+	ferredoxin--NADP reductase	NA	NA	NA	NA
WP_025212170.1\|1421489_1422188_-\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_025212171.1\|1422427_1422889_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.2e-35	49.3
WP_025212172.1\|1422946_1423657_-	RNA-binding protein S4	NA	NA	NA	NA
WP_025212173.1\|1423739_1424213_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_025212174.1\|1424471_1425812_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_025212175.1\|1426087_1427989_+	potassium transporter Kup	M1HZV6	Acanthocystis_turfacea_Chlorella_virus	5.9e-76	34.3
WP_025212176.1\|1428246_1429536_-	virulence factor family protein	NA	NA	NA	NA
WP_025212177.1\|1429535_1432178_-	bifunctional lysylphosphatidylglycerol flippase/synthetase MprF	NA	NA	NA	NA
WP_025212178.1\|1432984_1434046_+	DNA polymerase IV	NA	NA	NA	NA
WP_025212179.1\|1434101_1435055_-	hypothetical protein	NA	NA	NA	NA
WP_025212180.1\|1435072_1436788_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA

DBSCAN-SWA_2

1914512 : 1923502

Catovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025212570.1\|1914512_1916507_+	polysaccharide biosynthesis protein	K7Y9E1	Megavirus	5.0e-17	25.9
WP_025212571.1\|1917098_1917560_+	transcription/translation regulatory transformer protein RfaH	NA	NA	NA	NA
WP_025212572.1\|1918063_1919185_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	4.0e-24	29.1
WP_025212573.1\|1919281_1920553_+	UDP-N-acetyl-D-mannosamine dehydrogenase	M1HPJ2	Paramecium_bursaria_Chlorella_virus	1.0e-23	26.8
WP_025212574.1\|1920635_1921634_+	UDP-N-acetylglucosamine 4,6-dehydratase (inverting)	A0A1V0SAI8	Catovirus	1.2e-43	36.2
WP_025212575.1\|1921637_1922798_+	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase	A0A2K9L470	Tupanvirus	1.4e-35	30.9
WP_025212576.1\|1922794_1923502_+	pseudaminic acid cytidylyltransferase	A0A1B1IVD3	uncultured_Mediterranean_phage	1.0e-09	31.8

DBSCAN-SWA_3

2464915 : 2471184

uncultured_Caudovirales_phage(83.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025213005.1\|2464915_2466196_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	9.7e-99	53.9
WP_025213006.1\|2466196_2467591_+	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_025213007.1\|2467713_2468718_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_025213008.1\|2468806_2469808_-	glycosyl transferase family protein	A0A2H4JBY5	uncultured_Caudovirales_phage	9.7e-163	83.8
WP_025213009.1\|2469804_2470140_-	TusE/DsrC/DsvC family sulfur relay protein	A0A2H4J8B6	uncultured_Caudovirales_phage	2.7e-45	82.0
WP_025213010.1\|2470136_2470430_-	sulfurtransferase complex subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	1.7e-30	67.7
WP_025213011.1\|2470429_2470792_-	sulfurtransferase complex subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	5.2e-42	71.7
WP_025213012.1\|2470791_2471184_-	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	3.2e-53	79.8

DBSCAN-SWA_4

2745858 : 2808821

Pseudomonas_phage(23.08%)

protease,plate,tRNA,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025213238.1\|2745858_2746884_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_025213239.1\|2746847_2748638_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_025213240.1\|2748621_2749065_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_025213241.1\|2749077_2749575_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_025213242.1\|2749760_2751242_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_025213243.1\|2751272_2751833_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_025213244.1\|2752057_2752510_+	hypothetical protein	NA	NA	NA	NA
WP_025213245.1\|2752574_2753906_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_025213246.1\|2753924_2754686_+	type VI secretion system protein ImpK	NA	NA	NA	NA
WP_025213247.1\|2754682_2758507_+	type VI secretion system protein ImpL	NA	NA	NA	NA
WP_025213248.1\|2758503_2759586_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_025213249.1\|2759582_2760536_-	2-hydroxyacid dehydrogenase	M1HUW8	Acanthocystis_turfacea_Chlorella_virus	2.4e-17	25.9
WP_025213250.1\|2760848_2761742_-	hypothetical protein	NA	NA	NA	NA
WP_025213251.1\|2762164_2762665_+	hypothetical protein	NA	NA	NA	NA
WP_025213252.1\|2762875_2764156_+	HAAAP family serine/threonine permease	NA	NA	NA	NA
WP_025213253.1\|2765356_2767966_-	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	NA	NA	NA	NA
WP_025213254.1\|2768374_2768845_+	DUF1289 domain-containing protein	NA	NA	NA	NA
WP_025213255.1\|2769030_2769894_-	universal stress protein	NA	NA	NA	NA
WP_025213256.1\|2770072_2770678_+\|tRNA	tRNA hydroxylase	NA	NA	NA	NA
WP_025213257.1\|2770820_2771309_-	GFA family protein	NA	NA	NA	NA
WP_025213258.1\|2771508_2772123_-	DNA-3-methyladenine glycosylase 2 family protein	S4VP92	Pandoravirus	1.4e-07	31.3
WP_025213259.1\|2772146_2773229_-	bifunctional transcriptional activator/DNA repair protein Ada	A0A2K9L698	Tupanvirus	7.9e-17	42.9
WP_025213260.1\|2773375_2773834_+	hypothetical protein	NA	NA	NA	NA
WP_025213261.1\|2773903_2775358_-	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_025213262.1\|2775558_2776146_+	LysE family translocator	NA	NA	NA	NA
WP_025213263.1\|2776315_2777140_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_025213264.1\|2777277_2778240_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
WP_025213265.1\|2779537_2780362_+\|bacteriocin	lipid II-degrading bacteriocin	B5TK62	Pseudomonas_phage	7.4e-100	65.0
WP_025213266.1\|2780368_2780785_+	hypothetical protein	B5TK63	Pseudomonas_phage	2.7e-18	42.6
WP_025213267.1\|2780838_2781633_-	enoyl-ACP reductase	NA	NA	NA	NA
WP_025213268.1\|2781652_2783263_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.2e-18	32.9
WP_025213269.1\|2783264_2784284_-	ABC transporter permease	NA	NA	NA	NA
WP_025213270.1\|2784285_2785359_-	microcin C ABC transporter permease YejB	NA	NA	NA	NA
WP_025213271.1\|2785363_2787220_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_162178167.1\|2787216_2789046_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_025213273.1\|2789324_2790773_-	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_025213274.1\|2790872_2791640_-	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_025213275.1\|2791705_2792464_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_025213276.1\|2792552_2793005_+	ribonuclease HI	J9Q745	Salmonella_phage	8.9e-39	54.8
WP_025213277.1\|2793237_2794002_+	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	2.8e-37	38.6
WP_025213278.1\|2794302_2794917_+	GNAT family N-acetyltransferase	E4ZFP7	Streptococcus_phage	7.3e-20	39.6
WP_025213279.1\|2794882_2795776_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_025213280.1\|2795862_2796126_-	hypothetical protein	NA	NA	NA	NA
WP_025213281.1\|2796310_2796868_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.7e-15	33.5
WP_025213282.1\|2797045_2801242_+	hypothetical protein	NA	NA	NA	NA
WP_144238558.1\|2801745_2802000_-	hypothetical protein	NA	NA	NA	NA
WP_025213283.1\|2802554_2802884_+	hypothetical protein	B5TK57	Pseudomonas_phage	9.6e-27	59.0
WP_025213284.1\|2803125_2803476_+	metalloregulator ArsR/SmtB family transcription factor	A0A2H4J145	uncultured_Caudovirales_phage	1.9e-36	68.2
WP_025213285.1\|2803513_2804797_+	arsenic transporter	A0A2H4J144	uncultured_Caudovirales_phage	2.4e-182	77.3
WP_025213286.1\|2804937_2805903_-	DUF1853 family protein	NA	NA	NA	NA
WP_025213287.1\|2806090_2806981_+	NAD(+) kinase	NA	NA	NA	NA
WP_025213288.1\|2806980_2807952_+	serine/threonine protein phosphatase	NA	NA	NA	NA
WP_025213289.1\|2807948_2808821_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA

DBSCAN-SWA_5

4174164 : 4219301

Burkholderia_phage(39.39%)

capsid,plate,transposase,tail,head,integrase

attL 4195203:4195219|attR 4219589:4219605

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025214303.1\|4174164_4175016_-	DNA (cytosine-5-)-methyltransferase	A0A218M957	Mycobacterium_phage	4.4e-39	49.1
WP_080712578.1\|4174976_4175177_-	Com family DNA-binding transcriptional regulator	Q5ZQW8	Pseudomonas_phage	2.1e-08	50.8
WP_080712642.1\|4175179_4175563_-	DUF4376 domain-containing protein	A0A1S5R1J2	Pseudomonas_phage	3.4e-23	49.1
WP_025214305.1\|4176623_4177169_-\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	2.1e-47	56.2
WP_025214306.1\|4177161_4178283_-\|plate	baseplate protein	Q6QI99	Burkholderia_phage	7.7e-84	46.3
WP_025214307.1\|4178266_4178644_-\|plate	baseplate protein	Q6QIA0	Burkholderia_phage	1.5e-31	61.1
WP_025214308.1\|4178753_4179527_+	hypothetical protein	NA	NA	NA	NA
WP_025214309.1\|4179523_4180057_-\|plate	phage baseplate assembly protein V	NA	NA	NA	NA
WP_025214310.1\|4180053_4181106_-	late control protein D	A4JWL3	Burkholderia_virus	1.8e-66	41.6
WP_025214311.1\|4181093_4181300_-	membrane protein	Q6QIA3	Burkholderia_phage	9.6e-17	59.4
WP_025214312.1\|4181299_4182181_-\|tail	phage tail protein	A0A067ZI88	Vibrio_phage	7.1e-08	34.9
WP_025214313.1\|4182180_4184703_-\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	6.5e-139	39.2
WP_025214314.1\|4184724_4184985_+	hypothetical protein	NA	NA	NA	NA
WP_025214315.1\|4185044_4185359_-\|tail	phage tail assembly protein	Q6QIA8	Burkholderia_phage	3.0e-09	36.4
WP_025214316.1\|4185515_4185707_+	hypothetical protein	NA	NA	NA	NA
WP_025214317.1\|4185769_4186132_-	hypothetical protein	NA	NA	NA	NA
WP_025214318.1\|4187287_4187785_-	DUF4231 domain-containing protein	NA	NA	NA	NA
WP_080712643.1\|4187840_4188797_-	hypothetical protein	A0A2I7RNF6	Vibrio_phage	2.4e-62	41.5
WP_025214320.1\|4188936_4189878_-	SMEK domain-containing protein	NA	NA	NA	NA
WP_025214321.1\|4190021_4190390_-	hypothetical protein	NA	NA	NA	NA
WP_025214322.1\|4190855_4191548_-	hypothetical protein	NA	NA	NA	NA
WP_025214323.1\|4191644_4192169_-\|tail	phage major tail tube protein	Q6QIA9	Burkholderia_phage	3.2e-48	52.9
WP_025214324.1\|4192169_4193591_-\|tail	tail protein	A4JWK5	Burkholderia_virus	2.8e-171	63.4
WP_080712579.1\|4193594_4193834_-	hypothetical protein	NA	NA	NA	NA
WP_038436680.1\|4193830_4194313_-	hypothetical protein	NA	NA	NA	NA
WP_025214326.1\|4194312_4194744_-	DUF1320 domain-containing protein	Q6QIB3	Burkholderia_phage	7.6e-40	54.7
WP_025214327.1\|4194747_4195728_-\|capsid	major capsid protein	Q9JMM2	Wolbachia_phage	8.6e-63	42.6
4195203:4195219	attL	NA	NA	NA	NA
WP_025214328.1\|4195741_4196110_-\|head	head decoration protein	NA	NA	NA	NA
WP_025214329.1\|4196119_4196956_-	peptidase	Q6QIB7	Burkholderia_phage	3.9e-48	64.1
WP_144238586.1\|4197317_4198733_+	hypothetical protein	NA	NA	NA	NA
WP_025214331.1\|4198747_4200721_-	hypothetical protein	NA	NA	NA	NA
WP_025214332.1\|4201113_4202943_+	hypothetical protein	Q2P9X5	Enterobacteria_phage	9.4e-63	29.0
WP_025214333.1\|4202990_4204226_-	hypothetical protein	NA	NA	NA	NA
WP_025214334.1\|4204367_4204850_-	phage virion morphogenesis protein	Q6QIB8	Burkholderia_phage	4.6e-17	36.2
WP_038436683.1\|4204957_4205758_-\|capsid	minor capsid protein	A0A0A1IX74	Pseudomonas_phage	1.7e-85	60.6
WP_025214335.1\|4205759_4207142_-	DUF935 family protein	Q6QIC0	Burkholderia_phage	1.6e-139	53.9
WP_025214336.1\|4207138_4208743_-	hypothetical protein	A0A219VH72	Ochrobactrum_phage	7.1e-115	45.5
WP_025214337.1\|4208739_4209291_-	DUF3486 family protein	J9SH37	Pseudomonas_phage	1.3e-28	47.4
WP_025214338.1\|4209293_4209587_-	hypothetical protein	J9SNG3	Pseudomonas_phage	5.6e-26	64.6
WP_025214339.1\|4209583_4209889_-	hypothetical protein	J9STR5	Pseudomonas_phage	2.5e-13	41.7
WP_025214340.1\|4209905_4210124_-	hypothetical protein	NA	NA	NA	NA
WP_025214341.1\|4210120_4210621_-	hypothetical protein	J9Q7Y7	Salmonella_phage	2.9e-38	50.0
WP_144238587.1\|4211142_4212084_+	hypothetical protein	NA	NA	NA	NA
WP_025214343.1\|4212238_4212838_-	hypothetical protein	NA	NA	NA	NA
WP_025214344.1\|4212912_4213398_-	hypothetical protein	NA	NA	NA	NA
WP_049866966.1\|4213415_4213733_-	hypothetical protein	NA	NA	NA	NA
WP_025214346.1\|4213953_4214190_+	DNA-binding protein	Q6QID3	Burkholderia_phage	4.3e-29	84.0
WP_144238588.1\|4214198_4214411_+	hypothetical protein	NA	NA	NA	NA
WP_025214347.1\|4214407_4214710_+	helix-turn-helix domain-containing protein	Q5ZR02	Pseudomonas_phage	1.7e-25	62.2
WP_025214348.1\|4214719_4215646_+	hypothetical protein	J9RW58	Pseudomonas_phage	9.3e-67	55.2
WP_025214349.1\|4215649_4217404_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A0S4L2U5	Pseudomonas_phage	1.7e-191	59.0
WP_025214350.1\|4217403_4218585_+	AAA family ATPase	Q6QIE1	Burkholderia_phage	4.9e-129	61.9
WP_038436684.1\|4218586_4218907_+	hypothetical protein	J9RWC3	Pseudomonas_phage	7.0e-14	45.6
WP_025214352.1\|4218938_4219301_+	DNA-binding protein	Q6QIE8	Burkholderia_phage	3.0e-37	63.2
4219589:4219605	attR	NA	NA	NA	NA

DBSCAN-SWA_6

6102552 : 6155860

Burkholderia_phage(33.33%)

protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025215854.1\|6102552_6103059_-\|protease	ATP-dependent zinc protease	NA	NA	NA	NA
WP_025215855.1\|6103351_6104239_+	acyltransferase	NA	NA	NA	NA
WP_025215856.1\|6104239_6104818_-	DUF2780 domain-containing protein	NA	NA	NA	NA
WP_025215857.1\|6105115_6105523_+	hypothetical protein	NA	NA	NA	NA
WP_025215858.1\|6105629_6106205_+	hypothetical protein	NA	NA	NA	NA
WP_025215859.1\|6106960_6107206_+	cold shock domain-containing protein	A0A2H4N7Y6	Lake_Baikal_phage	6.3e-15	59.4
WP_025215860.1\|6107302_6108502_-	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	1.1e-11	29.7
WP_025215861.1\|6108725_6109583_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_025215862.1\|6109740_6110373_-	sarcosine oxidase subunit gamma family protein	NA	NA	NA	NA
WP_025215863.1\|6110565_6113583_-	sarcosine oxidase subunit alpha	NA	NA	NA	NA
WP_003177604.1\|6113579_6113909_-	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_003177603.1\|6113923_6115174_-	sarcosine oxidase subunit beta	NA	NA	NA	NA
WP_025215864.1\|6115195_6116449_-	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	1.5e-99	52.7
WP_025215865.1\|6116754_6117459_-	conjugal transfer protein TraX	NA	NA	NA	NA
WP_025215866.1\|6117654_6118695_+	low specificity L-threonine aldolase	NA	NA	NA	NA
WP_025215867.1\|6118849_6119950_-	glycine-betaine demethylase subunit GbcB	NA	NA	NA	NA
WP_025215868.1\|6120231_6121527_+	glycine-betaine demethylase subunit GbcA	NA	NA	NA	NA
WP_025215869.1\|6121641_6122886_-	metallophosphoesterase	NA	NA	NA	NA
WP_025215870.1\|6122913_6124782_-	hypothetical protein	NA	NA	NA	NA
WP_025215871.1\|6124936_6128389_-\|holin	choline dehydrogenase	NA	NA	NA	NA
WP_025215872.1\|6129525_6130092_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_025215873.1\|6130415_6131186_-	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_025215874.1\|6131198_6132419_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_025215875.1\|6132418_6134368_-	dimethylglycine demethylation protein DgcB	NA	NA	NA	NA
WP_025215876.1\|6134575_6136636_-	dimethylglycine demethylation protein DgcA	NA	NA	NA	NA
WP_025215877.1\|6136651_6137182_-	hypothetical protein	NA	NA	NA	NA
WP_014340593.1\|6137262_6138240_-	membrane dipeptidase	NA	NA	NA	NA
WP_025215878.1\|6138475_6138877_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_025215879.1\|6138979_6139234_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5NR91	Burkholderia_phage	3.2e-22	61.9
WP_025215880.1\|6139217_6139541_+	helix-turn-helix transcriptional regulator	A0A1S5NNJ5	Burkholderia_phage	3.7e-31	68.5
WP_025215881.1\|6139763_6140540_+	hypothetical protein	NA	NA	NA	NA
WP_025215882.1\|6140626_6141043_+	DUF3010 family protein	NA	NA	NA	NA
WP_025215883.1\|6141216_6142392_-	hypothetical protein	NA	NA	NA	NA
WP_025215884.1\|6142460_6143420_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_025215885.1\|6143640_6144585_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_025215886.1\|6144656_6145544_+	3-keto-5-aminohexanoate cleavage protein	NA	NA	NA	NA
WP_025215887.1\|6145728_6146694_+	L-carnitine dehydrogenase	NA	NA	NA	NA
WP_025215888.1\|6146875_6147352_+	4-hydroxybenzoyl-CoA thioesterase	NA	NA	NA	NA
WP_025215889.1\|6147374_6148538_+	gamma-butyrobetaine dioxygenase	NA	NA	NA	NA
WP_025215890.1\|6148919_6149183_+	hypothetical protein	NA	NA	NA	NA
WP_025215891.1\|6149326_6150430_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_025215892.1\|6151019_6152396_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_025215893.1\|6152825_6153773_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_025215894.1\|6153839_6154685_+\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_025215895.1\|6154681_6155860_+\|holin	choline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.0e-25	36.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007410

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection