CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007394	Escherichia coli strain ST2747 chromosome, complete genome	2 crisprs	DEDDh,c2c9_V-U4,DinG,cas3,cas14j,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	0	6	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007394_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007394_1

3656207-3656417

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGACGCGGGGAACAC	PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder

3 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP007394_1

>merge|NZ_CP007394|1|3656207-3656417|PILER-CR,CRISPRCasFinder
CGGTTTATCCCCGCTGACGCGGGGAACACACATGAATGTCGGTTCAGACCGTGTTTTTACCCGGTTTATCCCCGCTGGCCGGGGAACGCTGCCTCGGCGGCGGCTCTGCGCAACCGCGAAACGGTTTATCCCCGCTGGCGCGGGGAACACCGCCCGTTTGAACAAAAACGGGTATCTAACTGCGGTTTATCCCCGCTGACGCGGGGAACAC

>NZ_CP007394|1|1|3656207-3656417|PILER-CR
CGGTTTATCCCCGCTGACGCGGGGAACAC	ACATGAATGTCGGTTCAGACCGTGTTTTTACC
CGGTTTATCCCCGCTGGCCGGGGAACGCT	GCCTCGGCGGCGGCTCTGCGCAACCGCGAAACGGTTTATCCCCG
CTGGCGCGGGGAACACCGCCCGTTTGAAC	AAAAACGGGTATCTAACTGCGGTTTATCCCCG
CTGACGCGGGGAACAC

>NZ_CP007394|1|1|3656207-3656417|CRISPRCasFinder
CGGTTTATCCCCGCTGACGCGGGGAACAC	ACATGAATGTCGGTTCAGACCGTGTTTTTACC
CGGTTTATCCCCGCTGGCCGGGGAACGCT	GCCTCGGCGGCGGCTCTGCGCAACCGCGAAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCCCGTTTGAACAAAAACGGGTATCTAACTG
CGGTTTATCCCCGCTGACGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007394.1\|WP_025210796.1\|3655087_3656125_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP007394.1\|WP_001295182.1\|3648019_3648781_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP007394.1\|WP_025210801.1\|3665687_3666422_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP007394.1\|WP_051529559.1\|3662375_3665075_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP007394.1\|WP_000372390.1\|3653927_3654836_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP007394.1\|WP_025210793.1\|3650286_3650997_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP007394.1\|WP_025210794.1\|3651893_3652499_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP007394.1\|WP_025210798.1\|3658355_3659102_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP007394.1\|WP_000956460.1\|3665269_3665422_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP007394.1\|WP_000063172.1\|3656513_3656807_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP007394.1\|WP_001219242.1\|3649807_3650287_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP007394.1\|WP_025210795.1\|3652498_3653926_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP007394.1\|WP_001246104.1\|3651520_3651844_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP007394.1\|WP_000517476.1\|3651015_3651327_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP007394.1\|WP_025210799.1\|3660715_3662278_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP007394.1\|WP_000206445.1\|3659112_3660168_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP007394.1\|WP_000568924.1\|3648761_3649811_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP007394.1\|WP_000144858.1\|3656803_3657727_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP007394.1\|WP_025210797.1\|3657723_3658374_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP007394.1\|WP_000029335.1\|3660182_3660719_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862

Protein	Function_ID	Function_description	E-value
NZ_CP007394.1\|WP_025210796.1\|3655087_3656125_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP007394.1\|WP_001295182.1\|3648019_3648781_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP007394.1\|WP_025210801.1\|3665687_3666422_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.44583e-137
NZ_CP007394.1\|WP_051529559.1\|3662375_3665075_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP007394.1\|WP_000372390.1\|3653927_3654836_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP007394.1\|WP_025210793.1\|3650286_3650997_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	2.05946e-120
NZ_CP007394.1\|WP_025210794.1\|3651893_3652499_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	4.67371e-147
NZ_CP007394.1\|WP_025210798.1\|3658355_3659102_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	5.15747e-46
NZ_CP007394.1\|WP_000956460.1\|3665269_3665422_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	4.96653e-13
NZ_CP007394.1\|WP_000063172.1\|3656513_3656807_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.07297e-64
NZ_CP007394.1\|WP_001219242.1\|3649807_3650287_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP007394.1\|WP_025210795.1\|3652498_3653926_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP007394.1\|WP_001246104.1\|3651520_3651844_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP007394.1\|WP_000517476.1\|3651015_3651327_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP007394.1\|WP_025210799.1\|3660715_3662278_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP007394.1\|WP_000206445.1\|3659112_3660168_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	2.45802e-155
NZ_CP007394.1\|WP_000568924.1\|3648761_3649811_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP007394.1\|WP_000144858.1\|3656803_3657727_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.11358e-157
NZ_CP007394.1\|WP_025210797.1\|3657723_3658374_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	4.4001e-91
NZ_CP007394.1\|WP_000029335.1\|3660182_3660719_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	4.62446e-29

>NZ_CP007394.1|WP_025210796.1|3655087_3656125_+|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDVDADANLGGLTLQGMDDNAAGLGVMLELAKRLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEVFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGTSWHDVRLDNQQHIDKALPGRIERRCRDVIRIMLPLVKELAKAS
>NZ_CP007394.1|WP_000372390.1|3653927_3654836_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFIHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP007394.1|WP_025210795.1|3652498_3653926_-|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADESLPAVQSASVDVVWMAEQQLSPGQRYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATTAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP007394.1|WP_025210794.1|3651893_3652499_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHHGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP007394.1|WP_001246104.1|3651520_3651844_-|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP007394.1|WP_000517476.1|3651015_3651327_-|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP007394.1|WP_025210793.1|3650286_3650997_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKHVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKVAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP007394.1|WP_001219242.1|3649807_3650287_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP007394.1|WP_000568924.1|3648761_3649811_-|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP007394.1|WP_001295182.1|3648019_3648781_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
>NZ_CP007394.1|WP_000063172.1|3656513_3656807_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQISQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGVRLVSFLPVDNQ
>NZ_CP007394.1|WP_000144858.1|3656803_3657727_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>NZ_CP007394.1|WP_025210797.1|3657723_3658374_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESETFTIECRAFAPELRIGQQLCFNLRANPTICKAGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFILLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGADA
>NZ_CP007394.1|WP_025210798.1|3658355_3659102_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSAPDLLSAIISRRDYYTDAWWMVAVATTPDALYRLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNASDVLRNAYQQYQDSFRELKVSLPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTINQGPWLSKEEPCTSQE
>NZ_CP007394.1|WP_000206445.1|3659112_3660168_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTEQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP007394.1|WP_000029335.1|3660182_3660719_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIESQEWRFTALALVAAVAANVKAIDERQPFAAQLAAVMSEGRFTRLSAVKTPDELLRQLRRAVKLLNGSVNLISLADDIFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>NZ_CP007394.1|WP_025210799.1|3660715_3662278_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRYKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQTSFAPKDQRRWDDIWEDGLEAEKLREALLSLDHAFQFGPDSPSFMQDFEALTGDKVPVASLLPEIPGVQTTKFNKDHFIKRGVTEYLCPHCSALALFSLQLNAPAGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWLNVMPQDEADLPLPKKFDDLIFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICDEQNDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLNKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP007394.1|WP_051529559.1|3662375_3665075_-|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKSNCFGLADYFRQLGFADTEQAAQFFAWLLCWHDTGKFARSFQQLYLHPQLKVPEGARKNYEKISHSTLGYWLWHHYLSEYEELLPSSSLSPRKLKRVMEMWMPMTTGHHGRPPDRIDELDNFLPEDKAAARDFLLEIKVLFPLIEIPAFWDDDEGIELLKQLSWYISATVVLADWTGSSTRFFPRVAQAMDIKDYWQKALVQAQNALTVFPPKAQTAPFTGINTLFPFIEHPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLMAARKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVHSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVYRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKSCSLQRSSQVIVFTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDAPGDEWFGSAMRNSAYVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLSTCIAGVVKPYANGAHAWEMSVVRVRRSWWKKHRDEFSLLEGDAFRQWCIEQRQEPEMANVILVTDDESCGYSAMEGLTGKVG
>NZ_CP007394.1|WP_000956460.1|3665269_3665422_-|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCFTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP007394.1|WP_025210801.1|3665687_3666422_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRTNLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDKGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG

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Crispr_ID: NZ_CP007394_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007394_2

3682120-3682391

Unclear

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	PILER-CR

4 spacers

The CRISPR arrays of NZ_CP007394_2

>merge|NZ_CP007394|2|3682120-3682391|CRISPRCasFinder,CRT,PILER-CR
TGGTTTATCCCCGCTGACGCGGGGAACTCATCAGTGATATCCAGCATTGCGGAGCTAAACGCGGTTTATCCCCGCTGGCGCGGGGAACTCATCGGCATCACAACCGATGGAATAACCAGCTCGGTTTATCCCCGCTGGCGCGGGGAACTCCGATTGTATATATTGTCGCCGGGTTGATTTTCCGGTTTATCCCCGCTGGCGCGGGGAACTCGCAAATGAATCCTTCGCGCTGGACATCCTGCGCGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP007394|2|2|3682120-3682391|CRISPRCasFinder
TGGTTTATCCCCGCTGACGCGGGGAACTC	ATCAGTGATATCCAGCATTGCGGAGCTAAACG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	ATCGGCATCACAACCGATGGAATAACCAGCT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CGATTGTATATATTGTCGCCGGGTTGATTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GCAAATGAATCCTTCGCGCTGGACATCCTGCG
CGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP007394|2|1|3682120-3682391|CRT
TGGTTTATCCCCGCTGACGCGGGGAACTC	ATCAGTGATATCCAGCATTGCGGAGCTAAACG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	ATCGGCATCACAACCGATGGAATAACCAGCT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CGATTGTATATATTGTCGCCGGGTTGATTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GCAAATGAATCCTTCGCGCTGGACATCCTGCG
CGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP007394|2|2|3682121-3682391|PILER-CR
GGTTTATCCCCGCTGACGCGGGGAACTCA	TCAGTGATATCCAGCATTGCGGAGCTAAACGC
GGTTTATCCCCGCTGGCGCGGGGAACTCA	TCGGCATCACAACCGATGGAATAACCAGCTC
GGTTTATCCCCGCTGGCGCGGGGAACTCC	GATTGTATATATTGTCGCCGGGTTGATTTTCC
GGTTTATCCCCGCTGGCGCGGGGAACTCG	CAAATGAATCCTTCGCGCTGGACATCCTGCGC
GGTTTATCCCCGCTGGCGCGGGGAACTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007394.1\|WP_001130266.1\|3672304_3672880_+\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP007394.1\|WP_025210806.1\|3688763_3690998_-\|GTP-diphosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP007394.1\|WP_000059301.1\|3676070_3677525_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP007394.1\|WP_001071643.1\|3687876_3688668_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP007394.1\|WP_025210802.1\|3670765_3672037_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP007394.1\|WP_000210878.1\|3686011_3687649_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP007394.1\|WP_001309695.1\|3670322_3670688_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP007394.1\|WP_000021318.1\|3677594_3678380_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP007394.1\|WP_025210804.1\|3673883_3674663_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP007394.1\|WP_001199976.1\|3682729_3683401_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP007394.1\|WP_025210805.1\|3683693_3684566_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP007394.1\|WP_001098095.1\|3674640_3675978_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP007394.1\|WP_000098219.1\|3695399_3696740_-\|glucarate-dehydratase	unknown	unknown	gnl\|CDD\|211799
NZ_CP007394.1\|WP_001164554.1\|3678698_3679976_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP007394.1\|WP_000186450.1\|3692403_3695160_+\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
NZ_CP007394.1\|WP_000109536.1\|3672027_3672288_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP007394.1\|WP_000036723.1\|3684625_3685924_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP007394.1\|WP_025210807.1\|3696760_3698101_-\|glucarate-dehydratase	unknown	unknown	gnl\|CDD\|211799
NZ_CP007394.1\|WP_025210803.1\|3673026_3673887_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP007394.1\|WP_000046786.1\|3691045_3692347_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291

Protein	Function_ID	Function_description	E-value
NZ_CP007394.1\|WP_001130266.1\|3672304_3672880_+\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NZ_CP007394.1\|WP_025210806.1\|3688763_3690998_-\|GTP-diphosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP007394.1\|WP_000059301.1\|3676070_3677525_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.6361e-82
NZ_CP007394.1\|WP_001071643.1\|3687876_3688668_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	9.36315e-160
NZ_CP007394.1\|WP_025210802.1\|3670765_3672037_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	1.31032e-124
NZ_CP007394.1\|WP_000210878.1\|3686011_3687649_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP007394.1\|WP_001309695.1\|3670322_3670688_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	3.73821e-59
NZ_CP007394.1\|WP_000021318.1\|3677594_3678380_-\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.13125e-139
NZ_CP007394.1\|WP_025210804.1\|3673883_3674663_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	3.21999e-63
NZ_CP007394.1\|WP_001199976.1\|3682729_3683401_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.06379e-155
NZ_CP007394.1\|WP_025210805.1\|3683693_3684566_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.37213e-95
NZ_CP007394.1\|WP_001098095.1\|3674640_3675978_-\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.11469e-51
NZ_CP007394.1\|WP_000098219.1\|3695399_3696740_-\|glucarate-dehydratase	gnl\|CDD\|211799	TIGR03247, glucar-dehydr, glucarate dehydratase. Glucarate dehydratase converts D-glucarate (and L-idarate, a stereoisomer) to 5-dehydro-4-deoxyglucarate which is subsequently acted on by GarL, tartronate semialdehyde reductase and glycerate kinase (GenProp0716). The E. coli enzyme has been well-characterized.	0
NZ_CP007394.1\|WP_001164554.1\|3678698_3679976_+\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	5.08413e-29
NZ_CP007394.1\|WP_000186450.1\|3692403_3695160_+\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
NZ_CP007394.1\|WP_000109536.1\|3672027_3672288_+\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	4.39108e-42
NZ_CP007394.1\|WP_000036723.1\|3684625_3685924_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP007394.1\|WP_025210807.1\|3696760_3698101_-\|glucarate-dehydratase	gnl\|CDD\|211799	TIGR03247, glucar-dehydr, glucarate dehydratase. Glucarate dehydratase converts D-glucarate (and L-idarate, a stereoisomer) to 5-dehydro-4-deoxyglucarate which is subsequently acted on by GarL, tartronate semialdehyde reductase and glycerate kinase (GenProp0716). The E. coli enzyme has been well-characterized.	0
NZ_CP007394.1\|WP_025210803.1\|3673026_3673887_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	5.70937e-89
NZ_CP007394.1\|WP_000046786.1\|3691045_3692347_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0

>NZ_CP007394.1|WP_001164554.1|3678698_3679976_+|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRNTNNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGYWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP007394.1|WP_000021318.1|3677594_3678380_-|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILINNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP007394.1|WP_000059301.1|3676070_3677525_-|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWTLLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP007394.1|WP_001098095.1|3674640_3675978_-|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFIGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISESPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP007394.1|WP_025210804.1|3673883_3674663_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAVQGNSGPDVSLLRSLLGADEQAAAALLLAQRKNGTSMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDAPFITLEQRTENGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAESPAMQCLQLARAEQQRGATLIDGQTVAEKARKLWQDYLRQRMQP
>NZ_CP007394.1|WP_025210803.1|3673026_3673887_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAEQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGADKNATLPSGMQQLNIVPGALPDWLVSIENLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASATVFSQADVGVVDDWKVVLEALVTNIHAECQ
>NZ_CP007394.1|WP_001130266.1|3672304_3672880_+|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP007394.1|WP_000109536.1|3672027_3672288_+|ferredoxin-family-protein
MSVARNLWRVADAPHIVPADSVERQTVQRLINACPAGLFSLTPEGDLRVDYRGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP007394.1|WP_025210802.1|3670765_3672037_+|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTQALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGESMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRAPACELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDTLRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDVLQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL
>NZ_CP007394.1|WP_001309695.1|3670322_3670688_+|6-carboxytetrahydropterin-synthase-QueD
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHYYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>NZ_CP007394.1|WP_001199976.1|3682729_3683401_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLMPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP007394.1|WP_025210805.1|3683693_3684566_+|YgcG-family-protein
MRYFILIFTFVCSFVAAQPTIVPSLQQQVTDLTSSLNSQEKKELTYKLESIFNNTQVQIAVLIVPTTKDETIEKYATRVFDNWRLGDAKRNDGILIIVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAQGLELAINALNNQLTSQHQYPANPSEIESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSSVCISAIYLLDLFLFSDKTFSIAVFFFFFTFTTIMVFTCLCVLQKRASGRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGASGRW
>NZ_CP007394.1|WP_000036723.1|3684625_3685924_-|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP007394.1|WP_000210878.1|3686011_3687649_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP007394.1|WP_001071643.1|3687876_3688668_-|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVIDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP007394.1|WP_025210806.1|3688763_3690998_-|GTP-diphosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKNYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVMANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP007394.1|WP_000046786.1|3691045_3692347_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKALFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILVPQLEALLPKVRACLDSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVAGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLHNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NZ_CP007394.1|WP_000186450.1|3692403_3695160_+|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG
>NZ_CP007394.1|WP_000098219.1|3695399_3696740_-|glucarate-dehydratase
MSSQFSTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIKDNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVLTLVRNTFADRDAGGRGLQTFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKATPLPYQSQPDDKCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAESIVALAQRFPQARITLDPNGAWSLNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMAEFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGLTWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGLVQVPQKPGLGVEIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR
>NZ_CP007394.1|WP_025210807.1|3696760_3698101_-|glucarate-dehydratase
MATQSSPVITDMKVIPVAGHDSMLLNIGGAHNAYFTRNIVVLTDNAGHTGIGEAPGGEVIYQTLVDAIPMVLGQEVARLNKVVQQVHKGNQAADFDTFGKGAWTFELRVNAVAALEAALLDLLGKALNVPVCELLGPGKQREAITVLGYLFYIGDRTKTDLPYLENTPGNHEWYQLRHQKAMNSEAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDTVRALKKRFPDARITVDPNGAWLLDEAISLCKGLNDVLTYAEDPCGAEQGFSGREVMAEFRRATGLPVATNMIATNWREMGHAVMLNAVDIPLADPHFWTLSGAVRVAQLCDDWGLTWGCHSNNHFDISLAMFTHVGAAAPGNPTAIDTHWIWQEGDCRLTKNPLEIKNGKIAVPDVPGLGVELDWEQVQKAHEAYKRLPGGARNDAGPMQYLIPGWTFDRKRPVFGRH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP038506	Escherichia coli strain 28Eco12 plasmid p28Eco12, complete sequence	11835-11866	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP019283	Escherichia coli strain 13P484A plasmid p13P484A-3, complete sequence	42147-42178	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	CP042641	Escherichia coli strain NCYU-24-74 plasmid pNCYU-24-74-3, complete sequence	36520-36551	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP034821	Salmonella sp. SSDFZ54 plasmid pTB502, complete sequence	1557-1588	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP027443	Escherichia coli strain 2013C-3252 plasmid unnamed1, complete sequence	9506-9537	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP027575	Escherichia coli strain 2013C-4081 plasmid unnamed2	94756-94787	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP027223	Escherichia coli strain 2015C-3101 plasmid unnamed2	65534-65565	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP030188	Salmonella enterica strain SA20094620 plasmid pSA20094620.3, complete sequence	61916-61947	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP027590	Escherichia coli strain 2014C-3011 plasmid unnamed2	64165-64196	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP039862	Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS014880 plasmid p16-6773.2, complete sequence	20286-20317	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP033632	Escherichia coli isolate ECCNB12-2 plasmid pTB-nb1, complete sequence	119284-119315	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_AP018798	Escherichia coli strain E2855 plasmid pE2855-2, complete sequence	85099-85130	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	CP012494	Escherichia coli strain CFSAN004177 plasmid pCFSAN004177G_03, complete sequence	46688-46719	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	CP027320	Escherichia coli strain 2014C-3084 plasmid unnamed1	42116-42147	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NC_013370	Escherichia coli O111:H- str. 11128 plasmid pO111_2, complete sequence	87237-87268	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP026475	Escherichia coli strain KBN10P04869 plasmid pKBN10P04869B, complete sequence	81853-81884	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	MN510445	Escherichia coli strain JIE250 plasmid pJIE250_3, complete sequence	70500-70531	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	MN510447	Escherichia coli strain TZ20_1P plasmid pTZ20_1P, complete sequence	47861-47892	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP012491	Escherichia coli strain CFSAN004176 plasmid pCFSAN004176P_03, complete sequence	62997-63028	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	MH422554	Escherichia phage P1, complete genome	87194-87225	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NC_050152	Enterobacteria phage P7, complete genome	93995-94026	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	MH445380	Escherichia virus P1 isolate transconjugant 2(L-II), complete genome	58645-58676	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NC_031129	Salmonella phage SJ46, complete genome	77363-77394	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	MH445381	Escherichia virus P1, complete genome	56870-56901	0	1.0
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_KP453775	Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence	17440-17471	2	0.938
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP017632	Escherichia coli strain SLK172 plasmid pSLK172-1, complete sequence	122310-122341	2	0.938
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP030285	Escherichia coli strain E308 plasmid pLKSZ04, complete sequence	6029-6060	2	0.938
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	NZ_CP036204	Escherichia coli strain L725 plasmid punnamed2, complete sequence	15121-15152	2	0.938
NZ_CP007394_1	1.1\|3656236\|32\|NZ_CP007394\|PILER-CR,CRISPRCasFinder	3656236-3656267	32	MN510446	Escherichia coli strain SvETEC plasmid pSvP1_F, complete sequence	131402-131433	2	0.938
NZ_CP007394_2	2.2\|3682210\|31\|NZ_CP007394\|CRISPRCasFinder,CRT	3682210-3682240	31	NZ_CP032686	Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence	619475-619505	6	0.806
NZ_CP007394_2	2.2\|3682210\|31\|NZ_CP007394\|CRISPRCasFinder,CRT	3682210-3682240	31	NZ_CP032691	Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence	610791-610821	6	0.806
NZ_CP007394_2	2.6\|3682211\|31\|NZ_CP007394\|PILER-CR	3682211-3682241	31	NZ_CP032686	Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence	619475-619505	6	0.806
NZ_CP007394_2	2.6\|3682211\|31\|NZ_CP007394\|PILER-CR	3682211-3682241	31	NZ_CP032691	Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence	610791-610821	6	0.806
NZ_CP007394_1	1.4\|3656297\|31\|NZ_CP007394\|CRISPRCasFinder	3656297-3656327	31	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	495161-495191	7	0.774
NZ_CP007394_1	1.4\|3656297\|31\|NZ_CP007394\|CRISPRCasFinder	3656297-3656327	31	NZ_CP041042	Paracoccus sp. AK26 plasmid pAK4, complete sequence	80164-80194	7	0.774
NZ_CP007394_1	1.4\|3656297\|31\|NZ_CP007394\|CRISPRCasFinder	3656297-3656327	31	NZ_CP021819	Sinorhizobium meliloti strain M162 plasmid psymA, complete sequence	503133-503163	7	0.774
NZ_CP007394_2	2.4\|3682331\|32\|NZ_CP007394\|CRISPRCasFinder,CRT	3682331-3682362	32	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	1415894-1415925	7	0.781
NZ_CP007394_2	2.8\|3682332\|32\|NZ_CP007394\|PILER-CR	3682332-3682363	32	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	1415894-1415925	7	0.781
NZ_CP007394_1	1.4\|3656297\|31\|NZ_CP007394\|CRISPRCasFinder	3656297-3656327	31	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	213347-213377	8	0.742
NZ_CP007394_2	2.4\|3682331\|32\|NZ_CP007394\|CRISPRCasFinder,CRT	3682331-3682362	32	NZ_CP048285	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248a, complete sequence	155917-155948	9	0.719
NZ_CP007394_2	2.8\|3682332\|32\|NZ_CP007394\|PILER-CR	3682332-3682363	32	NZ_CP048285	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248a, complete sequence	155917-155948	9	0.719
NZ_CP007394_2	2.4\|3682331\|32\|NZ_CP007394\|CRISPRCasFinder,CRT	3682331-3682362	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2424468-2424499	10	0.688
NZ_CP007394_2	2.8\|3682332\|32\|NZ_CP007394\|PILER-CR	3682332-3682363	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2424468-2424499	10	0.688

1. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP038506 (Escherichia coli strain 28Eco12 plasmid p28Eco12, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

2. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP019283 (Escherichia coli strain 13P484A plasmid p13P484A-3, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

3. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to CP042641 (Escherichia coli strain NCYU-24-74 plasmid pNCYU-24-74-3, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

4. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP034821 (Salmonella sp. SSDFZ54 plasmid pTB502, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

5. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP027443 (Escherichia coli strain 2013C-3252 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

6. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP027575 (Escherichia coli strain 2013C-4081 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

7. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP027223 (Escherichia coli strain 2015C-3101 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

8. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP030188 (Salmonella enterica strain SA20094620 plasmid pSA20094620.3, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

9. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP027590 (Escherichia coli strain 2014C-3011 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

10. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP039862 (Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS014880 plasmid p16-6773.2, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

11. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP033632 (Escherichia coli isolate ECCNB12-2 plasmid pTB-nb1, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

12. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_AP018798 (Escherichia coli strain E2855 plasmid pE2855-2, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

13. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to CP012494 (Escherichia coli strain CFSAN004177 plasmid pCFSAN004177G_03, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

14. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to CP027320 (Escherichia coli strain 2014C-3084 plasmid unnamed1) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

15. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NC_013370 (Escherichia coli O111:H- str. 11128 plasmid pO111_2, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

16. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP026475 (Escherichia coli strain KBN10P04869 plasmid pKBN10P04869B, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

17. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to MN510445 (Escherichia coli strain JIE250 plasmid pJIE250_3, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

18. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to MN510447 (Escherichia coli strain TZ20_1P plasmid pTZ20_1P, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

19. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP012491 (Escherichia coli strain CFSAN004176 plasmid pCFSAN004176P_03, complete sequence) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

20. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to MH422554 (Escherichia phage P1, complete genome) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

21. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NC_050152 (Enterobacteria phage P7, complete genome) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

22. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to MH445380 (Escherichia virus P1 isolate transconjugant 2(L-II), complete genome) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

23. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NC_031129 (Salmonella phage SJ46, complete genome) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

24. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to MH445381 (Escherichia virus P1, complete genome) position: , mismatch: 0, identity: 1.0

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaccgtgtttttacc	Protospacer
********************************

25. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_KP453775 (Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence) position: , mismatch: 2, identity: 0.938

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaacgtgttttcacc	Protospacer
******************* ********.***

26. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP017632 (Escherichia coli strain SLK172 plasmid pSLK172-1, complete sequence) position: , mismatch: 2, identity: 0.938

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcagaacgtgttttcacc	Protospacer
******************* ********.***

27. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP030285 (Escherichia coli strain E308 plasmid pLKSZ04, complete sequence) position: , mismatch: 2, identity: 0.938

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgacggtttagaccgtgtttttacc	Protospacer
********* *****.****************

28. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to NZ_CP036204 (Escherichia coli strain L725 plasmid punnamed2, complete sequence) position: , mismatch: 2, identity: 0.938

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgacggtttagaccgtgtttttacc	Protospacer
********* *****.****************

29. spacer 1.1|3656236|32|NZ_CP007394|PILER-CR,CRISPRCasFinder matches to MN510446 (Escherichia coli strain SvETEC plasmid pSvP1_F, complete sequence) position: , mismatch: 2, identity: 0.938

acatgaatgtcggttcagaccgtgtttttacc	CRISPR spacer
acatgaatgtcggttcataacgtgtttttacc	Protospacer
***************** * ************

30. spacer 2.2|3682210|31|NZ_CP007394|CRISPRCasFinder,CRT matches to NZ_CP032686 (Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence) position: , mismatch: 6, identity: 0.806

atcgg-catcacaaccgatggaataaccagct	CRISPR spacer
-tcggtcatcacaaccgaaggaatatccaatc	Protospacer
 **** ************ ****** ***...

31. spacer 2.2|3682210|31|NZ_CP007394|CRISPRCasFinder,CRT matches to NZ_CP032691 (Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence) position: , mismatch: 6, identity: 0.806

atcgg-catcacaaccgatggaataaccagct	CRISPR spacer
-tcggtcatcacaaccgaaggaatatccaatc	Protospacer
 **** ************ ****** ***...

32. spacer 2.6|3682211|31|NZ_CP007394|PILER-CR matches to NZ_CP032686 (Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence) position: , mismatch: 6, identity: 0.806

atcgg-catcacaaccgatggaataaccagct	CRISPR spacer
-tcggtcatcacaaccgaaggaatatccaatc	Protospacer
 **** ************ ****** ***...

33. spacer 2.6|3682211|31|NZ_CP007394|PILER-CR matches to NZ_CP032691 (Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence) position: , mismatch: 6, identity: 0.806

atcgg-catcacaaccgatggaataaccagct	CRISPR spacer
-tcggtcatcacaaccgaaggaatatccaatc	Protospacer
 **** ************ ****** ***...

34. spacer 1.4|3656297|31|NZ_CP007394|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.774

gcctcggcggcggctctgcgcaaccgcgaaa	CRISPR spacer
gcctcggcggcgggtccgcgcaactcggcca	Protospacer
************* **.*******.  *  *

35. spacer 1.4|3656297|31|NZ_CP007394|CRISPRCasFinder matches to NZ_CP041042 (Paracoccus sp. AK26 plasmid pAK4, complete sequence) position: , mismatch: 7, identity: 0.774

gcctcggcggcggctctgcgcaaccgcgaaa	CRISPR spacer
gcggcggcggcggcgctgcgcgaccgcgcgc	Protospacer
**  ********** ******.****** .

36. spacer 1.4|3656297|31|NZ_CP007394|CRISPRCasFinder matches to NZ_CP021819 (Sinorhizobium meliloti strain M162 plasmid psymA, complete sequence) position: , mismatch: 7, identity: 0.774

gcctcggcggcggctctgcgcaa-----ccgcgaaa	CRISPR spacer
gccacggcggcagctctgcgcaagtcagccg-----	Protospacer
*** *******.***********     ***

37. spacer 2.4|3682331|32|NZ_CP007394|CRISPRCasFinder,CRT matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaatgaatccttcgcgctggacatcctgcg	CRISPR spacer
gcccagcagtcctgcgcgctggccatcctgcg	Protospacer
**  *  *.**** ******** *********

38. spacer 2.8|3682332|32|NZ_CP007394|PILER-CR matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaatgaatccttcgcgctggacatcctgcg	CRISPR spacer
gcccagcagtcctgcgcgctggccatcctgcg	Protospacer
**  *  *.**** ******** *********

39. spacer 1.4|3656297|31|NZ_CP007394|CRISPRCasFinder matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 8, identity: 0.742

gcctcggcggcggctctgcgcaaccgcgaaa	CRISPR spacer
tacctggcggcggctctgcgcgagcgcggca	Protospacer
  *..****************.* ****. *

40. spacer 2.4|3682331|32|NZ_CP007394|CRISPRCasFinder,CRT matches to NZ_CP048285 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248a, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaatgaatccttcgcgctggacatcctgcg	CRISPR spacer
caaaatgattccttcacgctggacaaatttgg	Protospacer
  ****** ******.*********  .*  *

41. spacer 2.8|3682332|32|NZ_CP007394|PILER-CR matches to NZ_CP048285 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248a, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaatgaatccttcgcgctggacatcctgcg	CRISPR spacer
caaaatgattccttcacgctggacaaatttgg	Protospacer
  ****** ******.*********  .*  *

42. spacer 2.4|3682331|32|NZ_CP007394|CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaatgaatccttcgcgctggacatcctgcg	CRISPR spacer
aagtccgtgtccgacgcgctggacatcctgcg	Protospacer
. .  .* .***  ******************

43. spacer 2.8|3682332|32|NZ_CP007394|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaatgaatccttcgcgctggacatcctgcg	CRISPR spacer
aagtccgtgtccgacgcgctggacatcctgcg	Protospacer
. .  .* .***  ******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1236666 : 1334814

Enterobacteria_phage(47.54%)

capsid,transposase,protease,tail,lysis,portal,head,tRNA,integrase,terminase

attL 1246818:1246864|attR 1297857:1297903

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000912355.1\|1236666_1238052_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	5.1e-45	34.8
WP_001143546.1\|1238087_1238609_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_000190286.1\|1238716_1238929_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_000729161.1\|1238930_1239797_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.7e-30	37.5
WP_000776555.1\|1240267_1240810_+	type 1 fimbrial protein subunit FimA	NA	NA	NA	NA
WP_000988364.1\|1241029_1241722_+	type 1 fimbria chaperone FimC	NA	NA	NA	NA
WP_025210268.1\|1241752_1244362_+	fimbrial biogenesis usher protein	NA	NA	NA	NA
WP_000691065.1\|1244374_1245382_+	type 1 fimbrin D-mannose specific adhesin FimH	NA	NA	NA	NA
WP_001309313.1\|1245392_1245908_+	fimbria assembly protein	NA	NA	NA	NA
WP_000805414.1\|1245910_1246543_-	fimbria biosynthesis transcriptional regulator FimZ	NA	NA	NA	NA
1246818:1246864	attL	NA	NA	NA	NA
WP_001299447.1\|1246877_1248041_-\|integrase	site-specific integrase	A0A088CD23	Shigella_phage	3.4e-199	86.3
WP_000446905.1\|1247896_1248268_-	helix-turn-helix domain-containing protein	M1FJ59	Enterobacteria_phage	2.1e-46	81.0
WP_000488407.1\|1248239_1248518_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	4.9e-48	97.8
WP_000763390.1\|1248565_1248784_-	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	4.9e-35	98.6
WP_077248689.1\|1248882_1249164_-	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	2.1e-46	97.8
WP_000129285.1\|1249174_1249732_-	phage N-6-adenine-methyltransferase	E5AGF8	Erwinia_phage	2.0e-61	62.3
WP_000682294.1\|1249724_1249886_-	DUF1317 family protein	A0A0N7CHV0	Escherichia_phage	7.7e-22	96.0
WP_000186833.1\|1249882_1250563_-	YqaJ viral recombinase family protein	B6DZ61	Enterobacteria_phage	5.1e-131	98.2
WP_000100847.1\|1250559_1251345_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000995433.1\|1251350_1251647_-	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	6.2e-49	99.0
WP_000233576.1\|1251722_1251929_-	phage encoded cell division inhibitor protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
WP_000259990.1\|1252524_1253280_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	1.4e-92	75.0
WP_001067458.1\|1253318_1253549_+	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	1.5e-21	68.0
WP_001182903.1\|1253617_1254157_+	hypothetical protein	M9NZI6	Enterobacteria_phage	1.2e-61	66.1
WP_001551200.1\|1254243_1255173_+	replication protein	A0A0M5M7Y1	Salmonella_phage	8.0e-111	64.1
WP_000788815.1\|1255169_1255871_+	hypothetical protein	M1FJ72	Enterobacteria_phage	2.4e-128	98.7
WP_025210269.1\|1255867_1256170_+	hypothetical protein	A0A0N6WES4	Escherichia_phage	3.3e-42	94.6
WP_001070442.1\|1256237_1256570_+	SMR family multidrug efflux protein EmrE	NA	NA	NA	NA
WP_001299444.1\|1256617_1256767_+	hypothetical protein	NA	NA	NA	NA
WP_021537018.1\|1256824_1258351_+	recombinase family protein	Q3HQV4	Burkholderia_phage	1.0e-30	27.8
WP_001445652.1\|1258815_1259367_+	Raf kinase inhibitor-like protein YbcL	NA	NA	NA	NA
WP_000881075.1\|1259376_1260174_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001303586.1\|1260290_1260392_+	hypothetical protein	NA	NA	NA	NA
WP_001054342.1\|1260388_1260844_+	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	5.4e-60	66.9
WP_000224916.1\|1260843_1261014_+	hypothetical protein	K7P7K0	Enterobacteria_phage	1.5e-12	67.9
WP_000774488.1\|1261006_1261297_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	4.3e-47	94.8
WP_001099716.1\|1261293_1261656_+	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	1.6e-59	95.7
WP_001307651.1\|1261652_1261793_+	YlcG family protein	K7PHH3	Enterobacteria_phage	8.5e-09	69.8
WP_001204783.1\|1261878_1262262_+	antitermination protein QuuD	A0A088CD47	Shigella_phage	8.8e-56	83.3
WP_025210270.1\|1262451_1263534_-	porin OmpC	Q1MVN1	Enterobacteria_phage	6.0e-166	79.8
WP_000839596.1\|1264107_1264323_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_001135256.1\|1264322_1264820_+	lysozyme	M1FJA0	Enterobacteria_phage	5.6e-87	95.2
WP_001228702.1\|1265036_1265243_+	hypothetical protein	H6WRZ6	Salmonella_phage	5.3e-31	98.5
WP_001139678.1\|1265271_1265424_+	hypothetical protein	K7PKL2	Enterobacteria_phage	3.1e-20	96.0
WP_000079510.1\|1265775_1266186_-	DUF1398 family protein	C6ZCX4	Enterobacteria_phage	9.8e-53	76.3
WP_032231044.1\|1266243_1266477_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.3e-21	94.4
WP_000453580.1\|1266865_1267411_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.8e-95	100.0
WP_001027292.1\|1267385_1269311_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	100.0
WP_025210271.1\|1269307_1269514_+\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_001358226.1\|1269510_1271112_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	8.8e-312	99.8
WP_000123248.1\|1271092_1272412_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.8e-233	98.6
WP_001358225.1\|1272421_1272754_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	2.5e-54	98.2
WP_000063250.1\|1272809_1273835_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.1e-188	97.9
WP_000158878.1\|1273876_1274272_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	7.4e-58	94.7
WP_000785282.1\|1274283_1274637_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	6.4e-61	97.4
WP_000975081.1\|1274648_1275227_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	99.5
WP_000683129.1\|1275223_1275619_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	8.5e-70	98.5
WP_025210272.1\|1275626_1276367_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	3.4e-128	96.7
WP_000479193.1\|1276382_1276805_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.2e-60	85.7
WP_000459457.1\|1276786_1277221_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_025210273.1\|1277213_1279775_+\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	94.8
WP_000847345.1\|1279771_1280101_+\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	8.1e-58	98.2
WP_001152502.1\|1280100_1280799_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	8.9e-131	97.8
WP_038428179.1\|1280804_1281548_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.9e-147	96.4
WP_000090891.1\|1281484_1282117_+\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	2.2e-96	99.5
WP_001228252.1\|1285726_1286326_+	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	3.4e-102	92.5
WP_025210275.1\|1291179_1293537_+\|tail	phage tail protein	A0A1X7QGG5	Escherichia_phage	1.7e-117	50.1
WP_001544317.1\|1293536_1293806_+	hypothetical protein	NA	NA	NA	NA
WP_025210276.1\|1293818_1294502_+\|tail	tail fiber domain-containing protein	A0A1X7QGH6	Escherichia_phage	1.1e-56	60.0
WP_000355609.1\|1294512_1294806_+	hypothetical protein	NA	NA	NA	NA
WP_000386784.1\|1295481_1296231_+	DNA-binding transcriptional activator AppY	NA	NA	NA	NA
WP_025210277.1\|1296479_1297433_-\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_001177464.1\|1297946_1298708_-	DNA-binding transcriptional regulator EnvY	NA	NA	NA	NA
1297857:1297903	attR	NA	NA	NA	NA
WP_001224574.1\|1298890_1299781_-	DUF4434 family protein	NA	NA	NA	NA
WP_025210278.1\|1299781_1302754_-	bacteriophage adsorption protein NfrA	NA	NA	NA	NA
WP_025210279.1\|1302740_1304978_-	phage adsorption protein NrfB	NA	NA	NA	NA
WP_021523035.1\|1305175_1306312_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_000769435.1\|1306692_1307250_-	DUF4304 domain-containing protein	NA	NA	NA	NA
WP_001328511.1\|1307261_1307960_-	RHS repeat-associated core domain-containing protein	A0A2H4JHK7	uncultured_Caudovirales_phage	3.1e-14	40.4
WP_000260286.1\|1308847_1309063_-	hypothetical protein	NA	NA	NA	NA
WP_001522501.1\|1309674_1310106_-	hypothetical protein	NA	NA	NA	NA
WP_000154314.1\|1310597_1311131_-	hypothetical protein	NA	NA	NA	NA
WP_001160804.1\|1315976_1316438_-	DcrB-related protein	NA	NA	NA	NA
WP_000103213.1\|1316465_1318367_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	7.1e-29	26.3
WP_025210281.1\|1319103_1320552_-	Cu(+)/Ag(+) sensor histidine kinase CusS	A0A1V0SGX0	Hokovirus	5.1e-11	26.5
WP_000770953.1\|1320541_1321225_-	copper response regulator transcription factor CusR	W8CYM9	Bacillus_phage	1.0e-30	35.1
WP_025210282.1\|1321381_1322764_+	Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC	NA	NA	NA	NA
WP_000709869.1\|1322787_1323120_+	Cu(+)/Ag(+) efflux RND transporter periplasmic metallochaperone CusF	NA	NA	NA	NA
WP_000717111.1\|1323135_1324359_+	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit CusB	NA	NA	NA	NA
WP_025210283.1\|1324370_1327514_+	Cu(+)/Ag(+) efflux RND transporter permease subunit CusA	S5VTK5	Leptospira_phage	3.7e-59	22.4
WP_000786320.1\|1327615_1328992_+	phenylalanine transporter	NA	NA	NA	NA
WP_001153132.1\|1329059_1330307_-	mechanosensitive ion channel YbdG	NA	NA	NA	NA
WP_025234898.1\|1330414_1331068_-	oxygen-insensitive NAD(P)H nitroreductase	NA	NA	NA	NA
WP_000360954.1\|1331161_1331530_-	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_000682518.1\|1331594_1331843_-	DUF1158 domain-containing protein	NA	NA	NA	NA
WP_025210284.1\|1331908_1333027_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_085948682.1\|1333445_1334814_+\|transposase	IS3-like element IS150 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	4.8e-112	99.5

DBSCAN-SWA_2

2092586 : 2148402

Escherichia_phage(57.78%)

transposase,lysis,head,tRNA,integrase,terminase

attL 2083481:2083496|attR 2129237:2129252

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2083481:2083496	attL	NA	NA	NA	NA
WP_001361837.1\|2092586_2093819_-	diguanylate cyclase DgcM	A0A127AWB9	Bacillus_phage	3.1e-17	39.5
WP_001599773.1\|2095532_2096906_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-53	33.1
WP_001157407.1\|2097034_2097970_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	5.9e-146	98.8
WP_001516465.1\|2098021_2099257_-\|integrase	site-specific integrase	A0A0U2JGI6	Escherichia_phage	8.4e-241	99.5
WP_000079604.1\|2099258_2099474_-	excisionase XisR	A0A0U2RY08	Escherichia_phage	1.8e-37	100.0
WP_001605349.1\|2099573_2099762_-	DUF1187 family protein	A0A0U2QL97	Escherichia_phage	1.2e-26	98.4
WP_032159264.1\|2099754_2099949_-	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	A0A0U2QQP4	Escherichia_phage	1.3e-31	98.4
WP_001004422.1\|2100012_2101065_-	recombinase RecT	A0A0U2S5Y9	Escherichia_phage	8.5e-117	63.6
WP_001605350.1\|2101076_2104148_-	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	0.0e+00	84.0
WP_001344816.1\|2104249_2104525_-	hypothetical protein	A0A0U2QW85	Escherichia_phage	4.0e-42	95.6
WP_001352098.1\|2104599_2104770_-	conserved protein, Rac prophage	A0A0U2SHB5	Escherichia_phage	3.6e-17	71.4
WP_000560223.1\|2104769_2104991_-	killing protein KilR	A0A0U2RTC4	Escherichia_phage	2.0e-36	98.6
WP_001312793.1\|2105432_2105921_+	superinfection exclusion protein B	NA	NA	NA	NA
WP_001169151.1\|2105917_2106073_-	YdaF family protein	M4QQ57	Salicola_phage	6.1e-08	55.3
WP_001326317.1\|2106083_2106263_-	hypothetical protein	NA	NA	NA	NA
WP_001551043.1\|2106526_2107003_-	DNA-binding transcriptional repressor RacR	NA	NA	NA	NA
WP_001551044.1\|2107126_2107423_+	toxin YdaS	A0A0R6PH31	Moraxella_phage	1.6e-09	43.5
WP_025210427.1\|2107445_2107868_+	hypothetical protein	A0A0U2RXZ9	Escherichia_phage	1.4e-67	92.9
WP_001396581.1\|2107945_2108734_+	hypothetical protein	G9L6A8	Escherichia_phage	2.0e-41	64.3
WP_000788969.1\|2108740_2109487_+	ATP-binding protein	V5UQI5	Shigella_phage	4.9e-111	78.5
WP_001605353.1\|2109509_2110271_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	5.5e-118	88.5
WP_001605354.1\|2110286_2110709_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	6.7e-65	92.1
WP_001100703.1\|2111804_2112956_+	DNA cytosine methyltransferase	Q8JKX6	Natrialba_phage	1.0e-22	36.9
WP_000016656.1\|2112923_2113913_-	hypothetical protein	NA	NA	NA	NA
WP_000138556.1\|2113912_2115304_-	ATPase	NA	NA	NA	NA
WP_000940319.1\|2115803_2116403_+	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	1.1e-105	92.0
WP_001605357.1\|2116402_2116693_+	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	8.2e-46	86.5
WP_000640161.1\|2116689_2117232_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	2.9e-76	75.7
WP_000506936.1\|2118276_2118705_+	cell envelope integrity protein TolA	NA	NA	NA	NA
WP_001348108.1\|2118876_2119251_+	hypothetical protein	NA	NA	NA	NA
WP_000839565.1\|2119502_2119718_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	1.3e-32	94.4
WP_001135310.1\|2119717_2120215_+	lysozyme RrrD	M1FJA0	Enterobacteria_phage	9.3e-90	96.4
WP_001228688.1\|2120431_2120617_+\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	3.6e-15	96.5
WP_001097895.1\|2120813_2122271_+	Trk system potassium uptake protein TrkG	NA	NA	NA	NA
WP_025210428.1\|2122408_2123200_+	ParB N-terminal domain-containing protein	R4TG31	Halovirus	8.2e-48	39.8
WP_001204037.1\|2123192_2124125_+	hypothetical protein	A0A1B1INP7	uncultured_Mediterranean_phage	1.4e-83	54.9
WP_000126788.1\|2124102_2124312_+	hypothetical protein	NA	NA	NA	NA
WP_000089447.1\|2124315_2125410_+	hypothetical protein	A0A0U2RXW9	Escherichia_phage	5.9e-113	80.5
WP_000625348.1\|2125390_2126692_+\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	3.6e-149	59.6
WP_000763704.1\|2126694_2128101_+	DUF4055 domain-containing protein	G8C7P4	Escherichia_phage	3.0e-186	69.0
WP_001351715.1\|2128084_2129197_+	hypothetical protein	I6PD76	Cronobacter_phage	4.2e-114	54.5
WP_000770042.1\|2129301_2130066_+	hypothetical protein	G8C7P6	Escherichia_phage	6.9e-84	64.2
2129237:2129252	attR	NA	NA	NA	NA
WP_000918487.1\|2130164_2131304_+	hypothetical protein	G8C7P7	Escherichia_phage	7.4e-159	75.0
WP_000634214.1\|2131526_2131922_+	hypothetical protein	NA	NA	NA	NA
WP_000524260.1\|2131921_2132305_+	hypothetical protein	A0A0P0I456	Acinetobacter_phage	2.2e-14	39.4
WP_001029815.1\|2132305_2132686_+	hypothetical protein	A0A059VF88	Pseudomonas_phage	1.1e-18	44.4
WP_000144678.1\|2132682_2133075_+	hypothetical protein	NA	NA	NA	NA
WP_025234901.1\|2133101_2134064_+	hypothetical protein	A0A059VG08	Pseudomonas_phage	4.5e-56	39.2
WP_012565075.1\|2134214_2134574_+	hypothetical protein	NA	NA	NA	NA
WP_051539322.1\|2139816_2140089_+	hypothetical protein	A0A077SK35	Escherichia_phage	5.5e-36	98.7
WP_025210440.1\|2140101_2143089_+	hypothetical protein	A0A077SK08	Escherichia_phage	0.0e+00	97.3
WP_001165936.1\|2143078_2143387_+	hypothetical protein	O21974	Escherichia_phage	5.4e-48	97.1
WP_025210442.1\|2143764_2144442_-	DUF2829 domain-containing protein	A0A1B0VBT1	Salmonella_phage	4.9e-126	98.2
WP_025210444.1\|2144639_2145128_-	single-stranded DNA-binding protein	A0A1B0VAF5	Salmonella_phage	3.2e-87	99.4
WP_025210445.1\|2145297_2145855_+	lysozyme	Q71TF3	Escherichia_phage	2.7e-106	99.5
WP_000132937.1\|2146139_2147159_-\|head	head processing protein	Q71TR6	Escherichia_phage	4.4e-179	96.8
WP_001312284.1\|2147271_2148402_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q9G0F2	Phage_Gifsy-1	9.2e-186	84.5

DBSCAN-SWA_3

2162744 : 2175866

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000896806.1\|2162744_2163473_+	hypothetical protein	Q71TJ9	Escherichia_phage	4.2e-139	100.0
WP_000660977.1\|2164411_2167699_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A077SL51	Escherichia_phage	0.0e+00	98.7
WP_025210464.1\|2167695_2168601_-	recombination-associated protein RdgC	A0A077SK17	Escherichia_phage	6.5e-158	97.0
WP_001177864.1\|2168593_2168878_-	hypothetical protein	Q71TA2	Escherichia_phage	1.7e-48	98.9
WP_025210465.1\|2169339_2170128_+	hypothetical protein	Q71TL4	Escherichia_phage	4.0e-119	99.2
WP_025210466.1\|2170167_2170590_+	hypothetical protein	Q71TL5	Escherichia_phage	2.3e-57	96.4
WP_001281116.1\|2170767_2171160_+	hypothetical protein	A0A077SLJ1	Escherichia_phage	2.0e-71	99.2
WP_001154687.1\|2172673_2173483_+	GIY-YIG nuclease family protein	A0A077SK46	Escherichia_phage	7.1e-156	97.8
WP_001285362.1\|2173651_2174848_+	ParA family protein	A0A077SL49	Escherichia_phage	1.6e-225	100.0
WP_000038866.1\|2174864_2175866_+	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	1.7e-178	100.0

DBSCAN-SWA_4

2181430 : 2196135

Enterobacteria_phage(42.86%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000024051.1\|2181430_2181769_+\|tail	phage tail protein	H6WZM2	Escherichia_phage	4.0e-28	50.0
WP_001605366.1\|2181768_2182467_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.5e-125	93.5
WP_001349921.1\|2182472_2183216_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	6.8e-145	95.5
WP_000090891.1\|2183152_2183785_+\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	2.2e-96	99.5
WP_025234914.1\|2183845_2187325_+	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	89.6
WP_001228228.1\|2187392_2187992_+	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	1.2e-102	93.0
WP_000741766.1\|2188056_2190432_+\|tail	phage tail protein	A0A1X7QGG5	Escherichia_phage	1.4e-167	69.3
WP_000654143.1\|2190431_2190713_+	hypothetical protein	A0A1X7QHA1	Escherichia_phage	1.6e-17	47.8
WP_025210478.1\|2190722_2191763_+\|tail	tail fiber domain-containing protein	A0A0E3M4A9	Enterobacteria_phage	5.4e-124	67.0
WP_000355601.1\|2191805_2192099_+	hypothetical protein	NA	NA	NA	NA
WP_025210479.1\|2192326_2192917_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	3.6e-24	38.3
WP_000836768.1\|2193233_2193467_-	cold shock protein YdfK	A0A192Y6D5	Salmonella_phage	1.1e-32	88.3
WP_120795384.1\|2193535_2193649_-	Rac prophage; protein YnaM	A0A1C9IHU6	Salmonella_phage	8.4e-07	80.6
WP_001157926.1\|2193988_2194162_+	hypothetical protein	NA	NA	NA	NA
WP_001295593.1\|2194426_2194861_-	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	1.4e-28	52.8
WP_000837902.1\|2195001_2196135_-	porin OmpN	Q1MVN1	Enterobacteria_phage	4.8e-118	58.8

DBSCAN-SWA_5

2855487 : 2867382

Enterobacteria_phage(30.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025210609.1\|2855487_2856234_-	glycosyltransferase	A0A1V0SAH6	Catovirus	2.7e-08	39.3
WP_025210610.1\|2856233_2857640_-	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	2.0e-49	29.5
WP_021562286.1\|2857645_2858107_-	GDP-mannose mannosyl hydrolase	NA	NA	NA	NA
WP_025210611.1\|2858109_2859075_-	GDP-L-fucose synthase	M1HWW2	Paramecium_bursaria_Chlorella_virus	4.2e-86	50.5
WP_158413305.1\|2859078_2861022_-	GDP-mannose 4,6-dehydratase	M1HVG7	Acanthocystis_turfacea_Chlorella_virus	1.3e-99	66.2
WP_025210617.1\|2861076_2861622_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	8.4e-52	58.2
WP_025210618.1\|2861626_2862505_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.5e-106	64.5
WP_001023641.1\|2862562_2863462_-	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	1.7e-28	34.8
WP_025210619.1\|2863461_2864547_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.0e-101	54.2
WP_000183060.1\|2864919_2865813_-	UTP--glucose-1-phosphate uridylyltransferase GalF	A0A127AW70	Bacillus_phage	1.0e-46	42.0
WP_025210620.1\|2865987_2867382_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	3.7e-19	32.2

DBSCAN-SWA_6

2917020 : 2957128

Escherichia_phage(61.9%)

capsid,portal,tail,lysis,plate,head,tRNA,holin,integrase,terminase

attL 2921309:2921336|attR 2955313:2955340

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000675144.1\|2917020_2918424_+	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	1.2e-33	29.4
WP_000137877.1\|2918420_2919143_+	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	3.7e-31	33.6
WP_000929408.1\|2919322_2919655_+	YegP family protein	NA	NA	NA	NA
WP_025210639.1\|2919802_2921164_+\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.2e-216	99.2
2921309:2921336	attL	NA	NA	NA	NA
WP_000468308.1\|2921436_2921655_-	prophage transcriptional regulator OgrK	A0A0F7LDQ9	Escherichia_phage	4.7e-38	100.0
WP_000882931.1\|2921736_2922900_-	phage late control D family protein	U5N3V4	Enterobacteria_phage	3.1e-205	99.5
WP_025210640.1\|2922899_2923379_-\|tail	phage tail protein	O64315	Escherichia_phage	3.3e-84	99.4
WP_025210641.1\|2923393_2925841_-\|tail	phage tail tape measure protein	U5N0T4	Enterobacteria_phage	0.0e+00	95.2
WP_000785970.1\|2925833_2925953_-\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	1.0e-15	100.0
WP_001031303.1\|2925985_2926261_-\|tail	phage tail assembly protein	A0A0F7LDQ8	Escherichia_phage	5.7e-41	100.0
WP_001251408.1\|2926317_2926836_-\|tail	phage major tail tube protein	A0A0F7LDZ1	Escherichia_phage	1.4e-93	100.0
WP_001286716.1\|2926848_2928039_-\|tail	phage tail sheath protein	A0A0F7LBW9	Escherichia_phage	1.6e-225	100.0
WP_025210642.1\|2928098_2928692_-	recombinase family protein	A0A0F7LA37	Escherichia_phage	8.7e-103	95.9
WP_025210643.1\|2928890_2929208_+	hypothetical protein	NA	NA	NA	NA
WP_025234921.1\|2929351_2929720_+	hypothetical protein	A0A0F7LBW5	Escherichia_phage	1.1e-63	99.2
WP_001008234.1\|2929740_2930184_+\|tail	tail fiber assembly protein	A0A0F7LDZ0	Escherichia_phage	2.2e-82	100.0
WP_025210644.1\|2930155_2930758_-\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	3.5e-99	90.5
WP_025234922.1\|2930757_2932083_-\|tail	phage tail protein	M1TAS6	Escherichia_phage	3.0e-183	69.0
WP_016236406.1\|2932079_2932691_-\|tail	phage tail protein I	A0A0F7LA36	Escherichia_phage	1.4e-116	99.5
WP_025210646.1\|2932683_2933592_-\|plate	baseplate assembly protein	A0A0F7LCJ3	Escherichia_phage	2.0e-162	99.7
WP_025210647.1\|2933596_2933944_-\|plate	baseplate assembly protein	A0A0F7LDQ1	Escherichia_phage	5.0e-58	99.1
WP_025210648.1\|2933940_2934576_-\|plate	phage baseplate assembly protein V	U5N3F0	Enterobacteria_phage	1.4e-111	98.6
WP_025210649.1\|2934676_2936029_-	adenylate/guanylate cyclase domain-containing protein	NA	NA	NA	NA
WP_025210650.1\|2936039_2936579_-	hypothetical protein	NA	NA	NA	NA
WP_025210651.1\|2936594_2937056_-	phage virion morphogenesis protein	O80313	Escherichia_phage	1.3e-45	65.3
WP_025210652.1\|2937048_2937516_-\|tail	phage tail protein	U5N0S7	Enterobacteria_phage	2.2e-80	96.8
WP_001440152.1\|2937478_2937652_-	hypothetical protein	Q7Y4E1	Escherichia_virus	2.3e-24	96.5
WP_023278421.1\|2937623_2938049_-\|lysis	LysB family phage lysis regulatory protein	Q858W0	Yersinia_virus	1.6e-66	97.2
WP_025210653.1\|2938036_2938462_-	hypothetical protein	A0A0F7LDU9	Escherichia_phage	4.7e-58	94.3
WP_001144101.1\|2938476_2938974_-	glycoside hydrolase family 104 protein	A0A0F7LBS0	Escherichia_phage	3.1e-93	100.0
WP_000123123.1\|2938973_2939255_-\|holin	holin	A0A0F7LA12	Escherichia_phage	1.3e-43	100.0
WP_000846409.1\|2939258_2939462_-\|tail	tail protein X	A0A0F7LCN2	Escherichia_phage	3.0e-31	100.0
WP_000988633.1\|2939461_2939971_-\|head	head completion/stabilization protein	U5N0S3	Enterobacteria_phage	1.1e-90	100.0
WP_025210654.1\|2940070_2940814_-\|terminase	terminase endonuclease subunit	A0A0F7LDU4	Escherichia_phage	7.3e-123	98.4
WP_001248574.1\|2940817_2941891_-\|capsid	phage major capsid protein, P2 family	Q94MH9	Enterobacteria_phage	1.8e-202	100.0
WP_025210655.1\|2942737_2944510_+\|terminase	terminase ATPase subunit family protein	A0A0F7LCK3	Escherichia_phage	0.0e+00	99.5
WP_025210656.1\|2944509_2945544_+\|portal	phage portal protein	Q858W8	Yersinia_virus	4.6e-200	98.8
WP_106121066.1\|2945855_2947748_-	hypothetical protein	NA	NA	NA	NA
WP_000548273.1\|2947878_2948343_-	hypothetical protein	NA	NA	NA	NA
WP_024174129.1\|2948356_2949265_-	hypothetical protein	NA	NA	NA	NA
WP_025210657.1\|2949387_2951661_-	replication endonuclease	A0A0F7LBQ2	Escherichia_phage	0.0e+00	97.4
WP_021540634.1\|2951650_2951926_-	DUF5405 family protein	M1TAP2	Escherichia_phage	8.6e-45	98.9
WP_001113264.1\|2951922_2952147_-	TraR/DksA family transcriptional regulator	S4TRY6	Salmonella_phage	2.9e-35	100.0
WP_001277954.1\|2952146_2952449_-	DUF5405 family protein	A0A0F7LDT6	Escherichia_phage	6.5e-46	98.0
WP_000217670.1\|2952736_2953237_-	hypothetical protein	M1SV55	Escherichia_phage	2.6e-92	100.0
WP_038428309.1\|2953414_2953690_-	hypothetical protein	Q1JS62	Enterobacteria_phage	2.8e-48	98.9
WP_001306384.1\|2953804_2954104_+	helix-turn-helix transcriptional regulator	Q1JS63	Enterobacteria_phage	2.5e-50	100.0
WP_025210659.1\|2954219_2955233_+\|integrase	site-specific integrase	Q83VS6	Escherichia_phage	3.1e-193	98.8
WP_001303579.1\|2955496_2955814_-	hypothetical protein	NA	NA	NA	NA
2955313:2955340	attR	NA	NA	NA	NA
WP_025210660.1\|2956228_2957128_+	lipid kinase YegS	A0A1V0SBJ0	Catovirus	9.8e-13	29.0

DBSCAN-SWA_7

2994352 : 3003795

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025210665.1\|2994352_2995489_+	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	5.5e-162	97.1
WP_025210666.1\|2995485_2997486_+	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.7
WP_001295429.1\|2997610_2998072_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_001295430.1\|2998113_2998584_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_001308766.1\|2998630_2999350_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001309587.1\|2999346_3001032_-	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	7.3e-304	99.5
WP_001240398.1\|3001253_3001985_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	2.8e-111	99.0
WP_001216963.1\|3002044_3002152_+	protein YohO	NA	NA	NA	NA
WP_000783144.1\|3002132_3002864_-	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001600159.1\|3002868_3003795_-	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	2.2e-23	30.8

DBSCAN-SWA_8

3541435 : 3556562

Enterobacteria_phage(76.92%)

integrase

attL 3537192:3537205|attR 3544540:3544553

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3537192:3537205	attL	NA	NA	NA	NA
WP_000162574.1\|3541435_3541918_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
WP_000124726.1\|3542679_3543888_+\|integrase	tyrosine-type recombinase/integrase	A0A1B5FPC6	Escherichia_phage	6.6e-105	50.1
WP_001183326.1\|3543891_3545850_+	NACHT domain-containing protein	X5JAK5	Clostridium_phage	8.8e-67	31.1
3544540:3544553	attR	NA	NA	NA	NA
WP_025210772.1\|3546067_3546640_-	Polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.4e-94	96.2
WP_000638629.1\|3546713_3547214_-	transactivation protein	NA	NA	NA	NA
WP_001283029.1\|3547210_3547945_-	hypothetical protein	Q7M2A2	Enterobacteria_phage	1.0e-129	98.8
WP_001149160.1\|3548496_3548763_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.9e-45	100.0
WP_038429560.1\|3548759_3549023_+	hypothetical protein	NA	NA	NA	NA
WP_038429561.1\|3548968_3549313_+	host cell division inhibitor Icd-like protein	Q7M2A7	Enterobacteria_phage	2.3e-39	81.1
WP_001244665.1\|3549305_3549593_+	hypothetical protein	Q7M2A0	Enterobacteria_phage	8.6e-48	97.9
WP_025210773.1\|3549585_3550041_+	hypothetical protein	Q7M298	Enterobacteria_phage	1.0e-63	97.3
WP_001149160.1\|3552214_3552481_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.9e-45	100.0
WP_001365039.1\|3552834_3553032_+	host cell division inhibitor Icd-like protein	Q7M2A7	Enterobacteria_phage	4.0e-28	100.0
WP_025263442.1\|3553356_3553758_+	hypothetical protein	Q7M298	Enterobacteria_phage	4.0e-51	95.8
WP_000856729.1\|3553893_3554214_+	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_025210774.1\|3554228_3556562_+	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	98.8

DBSCAN-SWA_9

4675454 : 4684911

Enterobacteria_phage(87.5%)

integrase

attL 4670670:4670683|attR 4684841:4684854

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4670670:4670683	attL	NA	NA	NA	NA
WP_001218969.1\|4675454_4676627_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	3.6e-209	92.2
WP_000022311.1\|4676679_4678365_-	AIPR family protein	D0UIM0	Aggregatibacter_phage	5.1e-180	54.2
WP_000446147.1\|4678652_4679225_-	Polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.9e-94	96.2
WP_000638628.1\|4679298_4679799_-	transactivation protein	NA	NA	NA	NA
WP_025210993.1\|4679795_4680530_-	hypothetical protein	Q7M2A2	Enterobacteria_phage	2.0e-128	98.4
WP_001149160.1\|4681082_4681349_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.9e-45	100.0
WP_025210994.1\|4681345_4681945_+	ash family protein	Q7M2A7	Enterobacteria_phage	2.5e-49	81.0
WP_001244665.1\|4681937_4682225_+	hypothetical protein	Q7M2A0	Enterobacteria_phage	8.6e-48	97.9
WP_162472404.1\|4683754_4684033_+	hypothetical protein	NA	NA	NA	NA
WP_077768635.1\|4684041_4684911_+	poxvirus D5 -like family protein	Q7M2A8	Enterobacteria_phage	2.6e-156	98.2
4684841:4684854	attR	NA	NA	NA	NA

DBSCAN-SWA_10

4911877 : 4919662

Morganella_phage(28.57%)

integrase

attL 4908907:4908920|attR 4927806:4927819

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4908907:4908920	attL	NA	NA	NA	NA
WP_000086148.1\|4911877_4912561_-	DNA methylase	A0A2K9VH43	Faecalibacterium_phage	2.0e-26	36.4
WP_014640311.1\|4912636_4912948_-	hypothetical protein	NA	NA	NA	NA
WP_077768653.1\|4912944_4913847_-	DUF1281 domain-containing protein	NA	NA	NA	NA
WP_000618111.1\|4914264_4914513_+	DinI-like family protein	A0A1W6JP10	Morganella_phage	1.7e-12	38.8
WP_025263465.1\|4914509_4914947_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	5.4e-25	48.4
WP_025263466.1\|4914946_4916218_+	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	2.4e-142	60.5
WP_000340829.1\|4916222_4916615_-	hypothetical protein	NA	NA	NA	NA
WP_001103690.1\|4916619_4917591_-	hypothetical protein	A0A222YXF2	Escherichia_phage	7.4e-67	42.9
WP_000633913.1\|4917819_4918464_+	AAA family ATPase	A0A222YXS3	Escherichia_phage	1.9e-39	43.0
WP_000239529.1\|4918457_4918733_+	hypothetical protein	NA	NA	NA	NA
WP_000016494.1\|4918870_4919662_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	9.4e-52	91.1
4927806:4927819	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007394

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection