CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP006837	Lysinibacillus varians strain GY32 chromosome, complete genome	4 crisprs	cas3,csa3,WYL,DEDDh,DinG,c2c9_V-U4,casR	0	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP006837_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006837_1

43036-43274

Orphan

Consensus_repeat	Method
AGCAAAGCGTCAGGCCCAAACAAGTCATTTACGTAAATAGAAGAAAAGCTATG	PILER-CR

2 spacers

csa3

The CRISPR arrays of NZ_CP006837_1

>merge|NZ_CP006837|1|43036-43274|PILER-CR
CAAACAAGTCATTTACGAAAATAAGAGAAGTACTAGGAAAACCCCTATGCTTTAAAACAGGGAATCTCCATGCGTTCTGGCTGAAAGCGAAGCGTCAGGCCCAAACAAGTCATTTACGTAAATAGAAGAAAAGCTATGCAACAGTAAAGACGTTGAAGAAGGGAATATCAAAGCGTTCTGGCCGAAAGCAAAGCGTCAGGCCCAAACAAGTCATTTACGTAAATAGAAGAAAAGCTATG

>NZ_CP006837|1|1|43036-43274|PILER-CR
CAAACAAGTCATTTACGAAAATAAGAGAAGTACTAGGAAAACCCCTATGCTTTAAA	ACAGGGAATCTCCATGCGTTCTGGCTGAAAGCGAAGCGTCAGGCCCAAACAAGTCATTTACG
TAAATAGAAGAAAAGCTATGCAACAGTAAAGACGTTGAAGAAGGGAATATCAAAGC	GTTCTGGCCGAAAGCAAAGCGTCAGGCCCAAACAAGTCATTTACGTAA
ATAGAAGAAAAGCTATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006837.1\|WP_024362946.1\|41755_42394_+\|deoxynucleoside-kinase	unknown	unknown	gnl\|CDD\|238836
NZ_CP006837.1\|WP_025218315.1\|30128_30692_+\|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	unknown	unknown	gnl\|CDD\|237411
NZ_CP006837.1\|WP_024362950.1\|45923_47198_-\|cation:dicarboxylase-symporter-family-transporter	unknown	unknown	gnl\|CDD\|183075
NZ_CP006837.1\|WP_024362948.1\|44152_45061_+\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|206779
NZ_CP006837.1\|WP_025218323.1\|50265_52053_+\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505
NZ_CP006837.1\|WP_038509323.1\|43461_43992_+\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|129813
NZ_CP006837.1\|WP_025218318.1\|36905_37241_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP006837.1\|WP_024362943.1\|38299_38632_+\|metal-sensing-transcriptional-repressor	unknown	unknown	gnl\|CDD\|197387
NZ_CP006837.1\|WP_024362956.1\|53009_53225_+\|YaaL-family-protein	unknown	unknown	gnl\|CDD\|378478
NZ_CP006837.1\|WP_024362954.1\|52073_52388_+\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NZ_CP006837.1\|WP_025218316.1\|31037_32318_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_CP006837.1\|WP_024362951.1\|47290_48169_-\|DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|378022
NZ_CP006837.1\|WP_024362944.1\|38689_38896_+\|copper-chaperone-CopZ	unknown	unknown	gnl\|CDD\|225328
NZ_CP006837.1\|WP_025218320.1\|38977_41386_+\|copper-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NZ_CP006837.1\|WP_024362955.1\|52399_52996_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NZ_CP006837.1\|WP_025218317.1\|32543_36056_-\|peptidase-S8	unknown	unknown	gnl\|CDD\|173810
NZ_CP006837.1\|WP_025218322.1\|48169_49432_-\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|214643
NZ_CP006837.1\|WP_025218319.1\|37272_38223_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NZ_CP006837.1\|WP_024362940.1\|36251_36767_-\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|223663
NZ_CP006837.1\|WP_025218321.1\|45254_45875_+\|RraA-family-protein	unknown	unknown	gnl\|CDD\|319245

Protein	Function_ID	Function_description	E-value
NZ_CP006837.1\|WP_024362946.1\|41755_42394_+\|deoxynucleoside-kinase	gnl\|CDD\|238836	cd01673, dNK, Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1.113), adenosine (EC 2.7.1.76), and thymidine (EC 2.7.1.21) kinases. They are key enzymes in the salvage of deoxyribonucleosides originating from extra- or intracellular breakdown of DNA.	3.28128e-62
NZ_CP006837.1\|WP_025218315.1\|30128_30692_+\|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	gnl\|CDD\|237411	PRK13525, PRK13525, pyridoxal 5'-phosphate synthase glutaminase subunit PdxT.	2.63072e-109
NZ_CP006837.1\|WP_024362950.1\|45923_47198_-\|cation:dicarboxylase-symporter-family-transporter	gnl\|CDD\|183075	PRK11283, gltP, glutamate/aspartate:proton symporter; Provisional.	0
NZ_CP006837.1\|WP_024362948.1\|44152_45061_+\|PAS-domain-S-box-protein	gnl\|CDD\|206779	cd11386, MCP_signal, Methyl-accepting chemotaxis protein (MCP), signaling domain. Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.	1.39771e-34
NZ_CP006837.1\|WP_025218323.1\|50265_52053_+\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
NZ_CP006837.1\|WP_038509323.1\|43461_43992_+\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|129813	TIGR00730, LOG_family_protein_YJL055W, TIGR00730 family protein. This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved].	1.67585e-57
NZ_CP006837.1\|WP_025218318.1\|36905_37241_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.14663e-21
NZ_CP006837.1\|WP_024362943.1\|38299_38632_+\|metal-sensing-transcriptional-repressor	gnl\|CDD\|197387	cd10152, SaCsoR-like_DUF156, Staphylococcus aureus copper-sensitive operon repressor (CsoR), and related domains; this family was previously known as part of DUF156. This domain family includes Staphylococcus aureus CsoR (SaCsoR). SaCsoR is Cu(I)-inducible, and regulates the expression of genes involved in copper homeostasis; it represses a genetically unlinked copA-copZ operon. copA encodes a copper efflux P-type ATPase, and copZ, a copper chaperone. This family belongs to a larger superfamily that contains various transcriptional regulators that respond to different stressors such as Cu(I), Ni(I), sulfite, and formaldehyde, and includes Mycobacterium tuberculosis CsoR (MtCsoR), Bacillus subtilis CsoR, and Thermus thermophilus CsoR. The latter three proteins do not belong to this family. CsoRs form homotetramers (dimer of dimers). In MtCsoR, within each dimer, two Cys residues on opposite subunits, along with a His residue, bind the Cu(I) ion (forming a triagonal S2N coordination complex, C-H-C). These residues are conserved in the majority of members of this superfamily, including this family, and a conserved Tyr and a Glu residue that facilitate allosteric regulation of DNA binding for CsoRs are also well conserved.	2.82772e-37
NZ_CP006837.1\|WP_024362956.1\|53009_53225_+\|YaaL-family-protein	gnl\|CDD\|378478	pfam10704, DUF2508, Protein of unknown function (DUF2508). This family is conserved in Firmicutes. Several members are annotated as being the protein YaaL. The function is not known.	1.51443e-15
NZ_CP006837.1\|WP_024362954.1\|52073_52388_+\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	5.22294e-38
NZ_CP006837.1\|WP_025218316.1\|31037_32318_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP006837.1\|WP_024362951.1\|47290_48169_-\|DNA-binding-domain-containing-protein	gnl\|CDD\|378022	pfam08664, YcbB, YcbB domain. YcbB is a DNA-binding domain.	6.64877e-48
NZ_CP006837.1\|WP_024362944.1\|38689_38896_+\|copper-chaperone-CopZ	gnl\|CDD\|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	4.96538e-19
NZ_CP006837.1\|WP_025218320.1\|38977_41386_+\|copper-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP006837.1\|WP_024362955.1\|52399_52996_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	2.98156e-126
NZ_CP006837.1\|WP_025218317.1\|32543_36056_-\|peptidase-S8	gnl\|CDD\|173810	cd07484, Peptidases_S8_Thermitase_like, Peptidase S8 family domain in Thermitase-like proteins. Thermitase is a non-specific, trypsin-related serine protease with a very high specific activity. It contains a subtilisin like domain. The tertiary structure of thermitase is similar to that of subtilisin BPN'. It contains a Asp/His/Ser catalytic triad. Members of the peptidases S8 (subtilisin and kexin) and S53 (sedolisin) clan include endopeptidases and exopeptidases. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. Serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of subtilisin. The serine residue here is the nucleophilic equivalent of the serine residue in the S8 family, while glutamic acid has the same role here as the histidine base. However, the aspartic acid residue that acts as an electrophile is quite different. In S53 the it follows glutamic acid, while in S8 it precedes histidine. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. There is a great diversity in the characteristics of their members: some contain disulfide bonds, some are intracellular while others are extracellular, some function at extreme temperatures, and others at high or low pH values.	5.67676e-86
NZ_CP006837.1\|WP_025218322.1\|48169_49432_-\|GHKL-domain-containing-protein	gnl\|CDD\|214643	smart00387, HATPase_c, Histidine kinase-like ATPases. Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.	2.27437e-21
NZ_CP006837.1\|WP_025218319.1\|37272_38223_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	4.14997e-110
NZ_CP006837.1\|WP_024362940.1\|36251_36767_-\|nucleoside-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	1.00997e-65
NZ_CP006837.1\|WP_025218321.1\|45254_45875_+\|RraA-family-protein	gnl\|CDD\|319245	cd16841, RraA_family, ribonuclease activity regulator RraA family. RraA protein family is named after the regulator of ribonuclease activity A (RraA), a protein that binds to RNase E and inhibits RNase E endonucleolytic cleavages. Members also include proteins with other functions, like a 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate (HMG/CHA) aldolase from Pseudomonas putida, which catalyzes the last step of the bacterial protocatechuate 4,5-cleavage pathway and the uncharacterized YER010Cp protein from yeast, an organism lacking RNAse E.	3.04587e-54

>NZ_CP006837.1|WP_024362946.1|41755_42394_+|deoxynucleoside-kinase
MTVPFVAVEGPIGVGKTSLAKEVAATFNYHLLKEIVDENPFLNKFYENIEEWSFQTEMFFLCNRYKQLTDIKKLRLAQKTSVVSDYHIFKNLIFAKRTLPPAEYEKYEEIYQILTKDMPVPNVVVYLHASVDTLMKRIAKRGREFEKMISREYMEQLVADYHTFTEHFEQLHPEIPVIRFNGDQLDFVKNPQDLQYVLKTIEDTLQQRSLQQ
>NZ_CP006837.1|WP_025218320.1|38977_41386_+|copper-translocating-P-type-ATPase
MRSELKETNLQITGMTCAACATRIEKGLKKMEGVEQATVNLALEKSSIKYDPAILSEVDFEKKIEALGYGVVKQKAELDITGMTCAACATRIEKGLNKLSGVTATVNLALEKASIEFNPTEVSVSDIIGKVEKLGYGAHQKADERATEDYREKAIKQQQQKFLFSAILSLPLLWTMVAHFSLTSFLYVPDFLMNPWVQLVLATPVQFIIGKQFYVGAYKALRNGSANMDVLVVMGTSAAYFYSVYQAIVTVNSHHGPHLYFETSAVLITLILLGKLFEAKAKGRSSEAIKKLMGLQAKSAIVVRDGVEKEVPLEEVVIGDILLVKPGEKIPVDGEVVEGTTAVDESMLTGESLPVDKKQGDVLYGSTINKNGFVKMSATKVGRDTALAQIIKVVEDAQGSKAPIQRLADQISGIFVPIVVGIAIVTFLVWILWVKPGEFTPALEVLIAVLVIACPCALGLATPTSIMAGSGRAAEFGILFKGGEHLEQTQRIDTVVVDKTGTVTHGKPILTDVVLATGQEEASFLSLIGAAEKQSEHPLAQAIVQGIEERSITLGDVQFFEAIPGYGVQATVSGQGVVIGTRKLMQQYDIDIQHILPTMETLEENGKTAMLAAINGQYAGLVAVADTVKDTSKEAIRRLQDMGITVIMMTGDNERTAQAIGQEVGVNHVIAEVLPEGKADEVKKLQATGKNVAMVGDGINDAPALATANIGMAIGTGTDVAMEAADITLIRGDLTSIADAIIMSRKTMRNIKQNLFWAFAYNTLGIPIAAMGLLAPWVAGAAMAFSSVSVVLNALRLQRVKL
>NZ_CP006837.1|WP_024362944.1|38689_38896_+|copper-chaperone-CopZ
MQNVTLNVQGMSCGHCVNAVEKSVGALAGVEQVTVNLADGLVDVAFDDAQVSLAQIKETIDDQGYEVE
>NZ_CP006837.1|WP_024362943.1|38299_38632_+|metal-sensing-transcriptional-repressor
MEDTVKEDACHTEETASCRKSHHPERVKKDLTTRLNRVEGQIRGIKGMIEKDVYCDDIITQLSATQSALNSVAKILLEGHLKGCVVDRLSEGDEAVLDELVVTIQKLMKK
>NZ_CP006837.1|WP_025218319.1|37272_38223_+|cation-transporter
MGHNHDHGHDHTHGANKKVLLLSFIIITSYMVIEAIGGFLTNSLALLSDAGHMLSDSISLAIALLAFIFGEKAASFSKTYGYKRFEILAAVLNGVTLILIALFIFFEAIERFANPPEVATTGMLIISVIGLLINIVVAWIMMRGGDTEDNLNMRGAFLHVLSDMLGSVGAIIAALVIMFFGWGWADPLASVIVALLVLRSGYFVTKSAIHVLMEGTPSNVDVQEIIQIMEQTEGVQSIHDLHIWTITSGTNALSCHAVVDDQLNIGESEHILREIEHNLEHKGIKHITIQLETAENRHDESILCNLKSEPVHHDHH
>NZ_CP006837.1|WP_025218318.1|36905_37241_+|winged-helix-turn-helix-transcriptional-regulator
MDEQVKQGEIEIGNGKHLDEETLFVVSQTFKALSDPTRIRILNLLCSDEHSVNDIAEILDLSQSTVSHQLRFLKNLRLVKFRREGTSLYYSKDDDHIMNLLKQAIEHATHN
>NZ_CP006837.1|WP_024362940.1|36251_36767_-|nucleoside-deaminase
MDIFEKDRIFMNQALEEAKKAALLGEVPIGAVLVYEGEIIARAHNLRETTQNATTHAELMVIQEACKKLGSWRLEQTTLYVTLEPCPMCAGAILQSRVPRVVYGARDIKAGCVDSLYHLLNDARFNHDCDVTEGILAEECGQILTDFFRALRERKKAEKKARKMAESSEPQ
>NZ_CP006837.1|WP_025218317.1|32543_36056_-|peptidase-S8
MKKWMKKSIALVASASLMVPAASAYATAPEKTAQHTEVEKSLIASNKEKALKYVKNDKEWISKDTIIVKHTGLAKNAHKNIGSKVIRSIPSLGYDVIQLKKGISLEKAVSYYAKQDGVKSVSPSYVYHSFANGADPKKKDMYHLNLLQMDKALELAGNHEVKVAVIDSGVDFKHPDLKSQVLPPYNAAAPANTTYNGDHGTHVAGIIGAAKDNNVGGHGINPNAKLLPIDVFNGEEGANDFVIAQGILYAIEQGADVINMSLGGYGESPLMKDAVKQAIDKGITIVAAAGNESTDEYSFPASYEGVISVGSTNDINKLSSYSNYGPSVDVVAPGEEIYSTVHDEKKGSSFVKFSGTSMAAPVVAGVASLLKSKHPNLKPHEVEAILEMTANNLGEKGYDLTYGHGLINPLKALQFNVNNLPKEYSETTEERIKNAKVLAKNTLNSEKGEFKQPNEKKWYKVDLDANEYAQLTLKGANKYDYALELYFYPTDSKEEVDPIHVNDVRVGKQEGYLYKADQKGTLLVGVKDYNGSYNLNGESNYVFTAQTTKDLPVDSLEMDKKENIQQFPFSTKGKNYTLLSKDQQSDQDYFTFSVKEPTTLRFDLSGIPGVTASMELYLKEELDAVPAENVNDEEMYEAYPIQTSYSADKGDGVNLIVDAIPGTEYVLNVSNQGSSAFSLDMFFSGGIENEETISESIIPYTLKGEVVTLPEDEDGLPLNEEMPEGNVENELLPLTQYQTKKDNQINNLFNMFMDPGAMGNPEDIALIMEQAVPFDIGQDKKAYFQTEFDEDYFLLKPEEDAVYGFQVKKGMNQIPAGTIFEYDEETNELLAVSSLSNDMGILSLLLGSTSNANDAKAVALKKDKTYVVKVMNQGARSAEPYTLKTSKLAAIPSDYKSDNNTTINAQAVQPGTIYKDHIIYQDDIDYYYYKQRGQDEIMSLLVSSVPMTNEQLNQLPKELQNAFKFSGSIIEDTNGNMEIDPKELETEIQFGQGNNIFELLLGIIGTTDVNTSFKAKKNHGYFIIINGMNLEQVSIHPYTLSMYKHNQVDEDKDSELINGVPTKPSKLTKKDNKWVASQYLNAGVPFGDKDYFELNIDSKRDVFFSLQTEKALDGVIRIIDAKGKTVGTFDLYGTEDPEVGTVELDKGTYYIEVSELNGKASTQPYTLEVQ
>NZ_CP006837.1|WP_025218316.1|31037_32318_+|serine--tRNA-ligase
MLDIKRVRDNFAEIKEMLLTRNEDLGNLDDFEALDTKRRELIAKAEELKAERNKVSEQISVMKRNKKNADEVIARMRQVGDEIKELDTQLNEVEDRFKDMMMRLPNVPHESVPVGTTEDDNVVEYTWGEVPTFDFDIKAHWDIATDLQIVDFERGAKVAGSRFLFYRGLGARLERALMSFMMDLHAEEHGYEEMLPPVIVNRDSLTGTGQLPKFEEDVFKLDDTDYFMIPTAEVPVTNFYRDEILPIEVLPQGFAAYSACFRSEAGSAGRDTRGLIRQHQFNKVELVRFVKPEESYEQLELLTGHAEKVLQLLGLPYRKLKMCTADLGFTAAKKYDLEVWIPAQNMYREISSCSNFEDFQARRANIRFRREPNAKPEYVHTLNGSGLAIGRTVAAILENYQQADGSVAIPEVLVPYMGGKKVIAPK
>NZ_CP006837.1|WP_025218315.1|30128_30692_+|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT
MKRVGVLALQGAVREHVRMLEALGCQTVLVKHKEQLEGLDGLILPGGESTTMRKLLDRYELIGPIRSLVQKGVPMFGTCAGLILLAKEVVDHDPHLAVMDVVVARNSYGRQVDSFEVNLNIQAIGEAIPAVFIRAPHIVSVGEGVEVLAEHDGKIVLARDGHLLGCSFHPELTTDLRIAKYFVTTMV
>NZ_CP006837.1|WP_038509323.1|43461_43992_+|TIGR00730-family-Rossman-fold-protein
MRIAVYCGSGLGNNPIYAEKASELGTVLAHHGHGIVYGGSKIGLMGKVADAALVAGGEVIGVMPTHLQKQEIVHAALTEIHFVESMHIRKAKMVELADAFIALPGGGGTLDEYFEVFTWAQIRLHEKPVILFNVNGFYDALLQHFSIMLEEGFIRPEHKALIRVATTAEEVLTMIK
>NZ_CP006837.1|WP_024362948.1|44152_45061_+|PAS-domain-S-box-protein
MQKNDTQVTDDLVVQAIERNIAIIRFDMNRKVAYVNELFAKTMGYTVEKMMGKDHKEFCFPNYVKSPEYERFWRNLAAGKSYQDKVERMDARGNSIWLEATYMPVFDNHSRRVIGVSKIATNITERQNTIVNVADQLKQMSTKLYSRSEAGIKNSENLLATIQQVSKESSENVKNLDQLQNQADSIKGIVKTIQGIASQTNLLALNAAIEAARAGEYGRGFDVVAKEVRKLSVRVEQSISEVKENVEGIVREVGQVTESITRISEEIEKTNGQITVTTSDFAEIASAAEALDERSKQFIEII
>NZ_CP006837.1|WP_025218321.1|45254_45875_+|RraA-family-protein
MEKVEISFKHLPTTAISDATGGHTNLRSDIKPLADHFKIAGRAVTVRLPDGENGAVLEAIRAASEGDILVIDAKGNRNRAVAGDFVISLAKGMGVQGFVVDGVIRDIAAIRELDFPVFSLGTTVAAGNKNGGGKVNVPIAIGGVTVQPGDYIIGDIDGVIVVPQEDAERIVAAAEAKVEKDEVRAQEAHVNGKASIIAYLDKVLTK
>NZ_CP006837.1|WP_024362950.1|45923_47198_-|cation:dicarboxylase-symporter-family-transporter
MKKKFKISLAAQILIGLILGIIIGGIFYGNPKVETYLQPLGDIFLHLIKMIVVPIIISTLIVGVAGTGDMKQLGRLGGKSLIYFEIITTVAIVVGLLSANLFQPGAGINMNELSQGDISKYVSTTEEVQHEGPFDIIVGIVPTNIIQSMAEGNMLAIIFFSVIFGLGVAAIGERGKPVLDFFQGVADAMFWVTNLVMKFAPIGVFGLIGVTVSKYGFASLIPLGKLAILVYATMLFFIFVILGLVAKFAGVNIFYLIRVLKDELILAFSTASSEAVLPRVMLKMEKLGAPKDIVSFVIPTGYSFNLDGSTLYQAIAALFIAQMYGIHLSIGEQITLMLVLMVTSKGIAGVPGVSFVVLLATLGTVGIPIEGLAFIAGIDRILDMGRTVVNVIGNSLASLVMAKWEGRFDKEKMKNYFKENENLA
>NZ_CP006837.1|WP_024362951.1|47290_48169_-|DNA-binding-domain-containing-protein
MRYFIVDDDRASRVMLKQIIEDSGLGTVIGEARNGVDAIPQILMTQPEFVLIDLLMPKLDGIATVEHLLQNRFEGQFIMISQVVNKEMVGEAYEQGIDFFIHKPINRIEVENVLRKTTEQFRLKNSLLVIRQSLTNIDLSEQINNKATSRDHIQSILNDMGIVGEIGSEDIIAIIETLLAHQHKIAPLPPLKELYEEIAAVTKSTPDEILKESKAIEQRVRRTILAAMINLANLGVVDYTNSEFEYYAPRYFDFKEIRQLMTQIEDHGNRKAKVNIKKFIQVLYSDILTKVN
>NZ_CP006837.1|WP_025218322.1|48169_49432_-|GHKL-domain-containing-protein
MYSKAFISRSSLTWIISIALLTAIGSEIKIIPFANTSFRFGLGTIIFFLCTLLRPTPIILAGIVTSIVTTTLRIAISYYTHNTSLIDGIYTHLPAGTFYLLFAICLQLLNIHQYREKPLKLGLLVAFSEVISNLAEQLLRFLVQSYTILFIHDLLILLAVALLRSFFVVGIYSSIVIAEQKKRVQEMLTIGSDLYVETLYLKKSMNHIETITANGFDLYRQLKAQGNRSESIQALHIAQEIHEVKKDSQRIYAGISKIVGDKSFGSLRLSELLHYIEDGNRKYSELLGKDIQFNISLDTDFLTKEHIALLALLNNLTANAIEAIEKQGIISIDIQQQEVDTVITVSDDGKGISESDLSIIFEPGYTTKYNVEGVAATGIGLSHVAELISKLNGSISVESNNYKTVFKIIIPTQTILTGET
>NZ_CP006837.1|WP_025218323.1|50265_52053_+|DNA-polymerase-III-subunit-gamma/tau
MTYQAFYRVYRPQSFREMSGQAHVKRTLQNALLANKTTHAYLFSGPRGTGKTSTAKIFAKALNCEHAPASEPCNECATCLSITDGSHPDVIEFDAASNSRVEEIRDIIEKVRFAPASSRFKVYIIDEVHMLSTSAFNALLKTLEEPPPHAVFILATTEPHKLPATIISRCQRFDFKRLSTNDIIERMKVVLEDIELPFEEQGLKVIAQSAAGGMRDALSLLDQVVSFSGEMLKLEDALLVTGSISQDVFYDLAEALKVKDVAQMLALLEQLIADGKDPLRLSEDLITFFRDLLLLQTSENLAELLELVSPEERVFALAHDFAPDMLYGYIDILAKTQQEMRFSHHTKIYLETALLKMTQFSGGVVNQTAPSSEAVMSPELAQKIIALEQMVQQLSLQIQNGAPSQATQVAKEQRPRAKSPNGYKAPTGRIQEVLKDATKQDVQRVKAVWAQALNQLQKSQSALLAEAEPVAASSSAFVLKFKYDIHCQMVADNQMLKAQFTQLIAGQTGTMYEMLCTPEETWLKLREEFIRDHGLHQKKAPLANDDPNVELLEPPPAEMPEEPFIDDAQPLASQDPLVTEAEKLFGKDFIEIIED
>NZ_CP006837.1|WP_024362954.1|52073_52388_+|YbaB/EbfC-family-nucleoid-associated-protein
MRGMGNMQGMMKKMQKMQKEMMEAQEALNAEQFEGVAGGGMVKVTVTGQREVVEVNLDTSVVDPDDIEMLQDLIVVATNEALKKVEEKTNATMGKFTQGMNLPF
>NZ_CP006837.1|WP_024362955.1|52399_52996_+|recombination-protein-RecR
MYYPEPISKLIDSFMKLPGIGPKTAARLAFFVLTMKEDDVLSFSKALIDAKRNLSYCSVCGNITDVDPCHICTDKQRDASVICVVQDTKDVIAMEKMRDYHGKYHVLQGAISPMDGIGPEDINVASLLVRLQDETVQELILATNSTIEGEATAMYISRLVKPSGIRTTRIAHGLPVGGDLEYADEVTLSKAMEGRREL
>NZ_CP006837.1|WP_024362956.1|53009_53225_+|YaaL-family-protein
MFFRNKGKLKREFDEKLVNLIKQTKEDLQQAKLIEELLNDYDLEVIAQRKAAESIHFYLFKEARIRRVLIK

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Crispr_ID: NZ_CP006837_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006837_2

353579-353680

Orphan

Consensus_repeat	Method
AAATTGTTTGAGTGACTGGCACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006837_2

>merge|NZ_CP006837|2|353579-353680|CRISPRCasFinder
AAATTGTTTGAGTGACTGGCACTGCCGCAACCCTCGCTGATGCGAGGGTTTTTGCGTCTTGTGCCTTGAGTGGTTGCAAGAATTGTTTGAGTGACTGGCACT

>NZ_CP006837|2|1|353579-353680|CRISPRCasFinder
AAATTGTTTGAGTGACTGGCACT	GCCGCAACCCTCGCTGATGCGAGGGTTTTTGCGTCTTGTGCCTTGAGTGGTTGCAA
GAATTGTTTGAGTGACTGGCACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006837.1\|WP_025218488.1\|353684_356708_-\|response-regulator	unknown	unknown	gnl\|CDD\|225519
NZ_CP006837.1\|WP_024364655.1\|361642_362200_+\|superoxide-dismutase-family-protein	unknown	unknown	gnl\|CDD\|238186
NZ_CP006837.1\|WP_029747446.1\|352322_352964_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP006837.1\|WP_038509369.1\|351720_352227_-\|zf-HC2-domain-containing-protein	unknown	unknown	gnl\|CDD\|379219
NZ_CP006837.1\|WP_025218485.1\|349559_350447_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379352
NZ_CP006837.1\|WP_025218490.1\|358081_359209_-\|response-regulator	unknown	unknown	gnl\|CDD\|226456
NZ_CP006837.1\|WP_024364657.1\|359755_360547_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|226112
NZ_CP006837.1\|WP_025218492.1\|363770_364766_+\|TAXI-family-TRAP-transporter-solute-binding-subunit	unknown	unknown	gnl\|CDD\|270285
NZ_CP006837.1\|WP_025218481.1\|346613_347282_+\|M15-family-metallopeptidase	unknown	unknown	gnl\|CDD\|350620
NZ_CP006837.1\|WP_025218493.1\|364973_365489_+\|DUF1850-domain-containing-protein	unknown	unknown	gnl\|CDD\|378093
NZ_CP006837.1\|WP_025218483.1\|348325_348847_-\|SHOCT-domain-containing-protein	unknown	unknown	gnl\|CDD\|378276
NZ_CP006837.1\|WP_174412981.1\|357063_358029_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NZ_CP006837.1\|WP_025218486.1\|351329_351668_+\|phnA-family-protein	unknown	unknown	gnl\|CDD\|225380
NZ_CP006837.1\|WP_024362724.1\|365485_367522_+\|TRAP-transporter-permease	unknown	unknown	gnl\|CDD\|273983
NZ_CP006837.1\|WP_162832718.1\|367758_367902_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006837.1\|WP_025218487.1\|353136_353577_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006837.1\|WP_158497862.1\|350583_350751_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006837.1\|WP_025218491.1\|362777_363344_+\|superoxide-dismutase-family-protein	unknown	unknown	gnl\|CDD\|376292
NZ_CP006837.1\|WP_137036932.1\|348945_349158_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP006837.1\|WP_025218482.1\|347404_348307_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP006837.1\|WP_025218488.1\|353684_356708_-\|response-regulator	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	5.1065e-43
NZ_CP006837.1\|WP_025218493.1\|364973_365489_+\|DUF1850-domain-containing-protein	gnl\|CDD\|378093	pfam08905, DUF1850, Domain of unknown function (DUF1850). This family of proteins are functionally uncharacterized. Some members of this family appear to be misannotated as RocC an amino acid transporter from B. subtilis.	3.366e-17
NZ_CP006837.1\|WP_025218485.1\|349559_350447_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379352	pfam13730, HTH_36, Helix-turn-helix domain.	2.89036e-08
NZ_CP006837.1\|WP_038509369.1\|351720_352227_-\|zf-HC2-domain-containing-protein	gnl\|CDD\|379219	pfam13490, zf-HC2, Putative zinc-finger. This is a putative zinc-finger found in some anti-sigma factor proteins.	7.72993e-08
NZ_CP006837.1\|WP_024364657.1\|359755_360547_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|226112	COG3584, COG3584, Uncharacterized protein conserved in bacteria [Function unknown].	8.69366e-45
NZ_CP006837.1\|WP_025218481.1\|346613_347282_+\|M15-family-metallopeptidase	gnl\|CDD\|350620	cd14845, L-Ala-D-Glu_peptidase_like, L-Ala-D-Glu peptidase, also known as L-alanyl-D-glutamate endopeptidase. This L-Ala-D-Glu peptidase family includes L-alanyl-D-glutamate peptidase (bacteriophage T5) (also known as L-alanoyl-D-glutamate endopeptidase), and Ply118 and Ply500 L-Ala-D-Glu peptidase. Bacteriophage endolysin degrades the peptidoglycan of the bacterial host from within, leading to cell lysis and release of progeny virions. The bacteriophage endolysin Ply118 cleaves between L-Ala and D-Glu residues of Listeria cell wall peptidoglycan. This family belongs to the MEROPS peptidase M15 subfamily C.	5.80998e-32
NZ_CP006837.1\|WP_137036932.1\|348945_349158_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.0015236
NZ_CP006837.1\|WP_025218483.1\|348325_348847_-\|SHOCT-domain-containing-protein	gnl\|CDD\|378276	pfam09851, SHOCT, Short C-terminal domain.	5.81912e-07
NZ_CP006837.1\|WP_174412981.1\|357063_358029_+\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	4.03682e-58
NZ_CP006837.1\|WP_025218486.1\|351329_351668_+\|phnA-family-protein	gnl\|CDD\|225380	COG2824, PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism].	8.40994e-67
NZ_CP006837.1\|WP_024362724.1\|365485_367522_+\|TRAP-transporter-permease	gnl\|CDD\|273983	TIGR02123, conserved_inner_membrane_protein, TRAP transporter, 4TM/12TM fusion protein. In some species, the 12-transmembrane spanning and 4-transmembrane spanning components of tripartite ATP-independent periplasmic (TRAP)-type transporters are fused. This model describes such transporters, found in the Archaea and in Bacteria. [Transport and binding proteins, Unknown substrate].	0
NZ_CP006837.1\|WP_025218491.1\|362777_363344_+\|superoxide-dismutase-family-protein	gnl\|CDD\|376292	pfam00080, Sod_Cu, Copper/zinc superoxide dismutase (SODC). superoxide dismutases (SODs) catalyze the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SOD1 gene cause familial amyotrophic lateral sclerosis (Lou Gehrig's disease). Structure is an eight-stranded beta sandwich, similar to the immunoglobulin fold.	9.58446e-48
NZ_CP006837.1\|WP_024364655.1\|361642_362200_+\|superoxide-dismutase-family-protein	gnl\|CDD\|238186	cd00305, Cu-Zn_Superoxide_Dismutase, Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SOD1 gene causes familial amyotrophic lateral sclerosis (Lou Gehrig's disease). Cytoplasmic and periplasmic SODs exist as dimers, whereas chloroplastic and extracellular enzymes exist as tetramers. Structure supports independent functional evolution in prokaryotes (P-class) and eukaryotes (E-class) [PMID:.8176730].	2.12403e-49
NZ_CP006837.1\|WP_025218492.1\|363770_364766_+\|TAXI-family-TRAP-transporter-solute-binding-subunit	gnl\|CDD\|270285	cd13567, PBP2_TtGluBP, Substrate binding domain of Thermus thermophilus GluBP (TtGluBP) of TAXI family of the tripartite ATP-independent periplasmic transporters; contains the type 2 periplasmic binding protein fold. This subgroup includes TtGluBP of TAXI-TRAP family and closely related proteins. TRAP transporters are comprised of an SBP (substrate-binding protein) and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function.	1.72628e-124
NZ_CP006837.1\|WP_025218490.1\|358081_359209_-\|response-regulator	gnl\|CDD\|226456	COG3947, COG3947, Response regulator containing CheY-like receiver and SARP domains [Signal transduction mechanisms].	7.29699e-52
NZ_CP006837.1\|WP_029747446.1\|352322_352964_-\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	4.28752e-57

>NZ_CP006837.1|WP_025218487.1|353136_353577_+|hypothetical-protein
MLSIYTLLLYIHILSAVLSIGPLFVVLVIVKKMRTAAHVEMPPYIQVFQGAITIVKHAGHVLVASGILLMWRGGYPWTTSWVILTFLVMGGSIVFLARAFKPTIRTFDTPAYHQQKFASLLQRKAWIYIVLLLIMLWLMVAKPVLW
>NZ_CP006837.1|WP_029747446.1|352322_352964_-|HD-domain-containing-protein
MILIGIHQFFTSLNDLERIIRCPGRFKFEEHNVAAHSWKVSQYAMFFATLEEMNGATVNWKSLYEKTINHDFAEVFIGDIKTPVKHASPELKQMLAHVEEKMMEKFIMNEIPKEFQDIFFERMKEGKDETLEGRLLEFADKLDQFYEAFAELKRGNTDMEFVHMYQTALSKLLLIPLPATVRYFRTEILKDAVKEKTHIDIQALTNEVLDTNK
>NZ_CP006837.1|WP_038509369.1|351720_352227_-|zf-HC2-domain-containing-protein
MSHECSIVEDLLPLYKAHGLQADTTEFIEQHLATCKSCQQLAATQLSTNQNLSMKSTLTFFHLVFIVLSFMFALNSSLLGNHKSFVILYGLFGCLTYLFYKNIWIVFAISSIPVFVWAIINNFSNPLYMKNFSFIDIGSLIVGASYIALLHTIFALLGAAFAIVLRRL
>NZ_CP006837.1|WP_025218486.1|351329_351668_+|phnA-family-protein
MAAYPNCPKCNSEYTYEDGTNFVCPECAHEWSTNATEQESDTLIVKDANGNLLADGDAVTIIKDLKVKGSSSTLKIGTKVKSIRLVEGDHNIDCKIDGFGAMKLKSEFVKKA
>NZ_CP006837.1|WP_158497862.1|350583_350751_+|hypothetical-protein
MTHFEYMEQQGQLTIFDLEDQYEEMQFKKLSTNVNKPVDKRTFIVPRIRGYIVRR
>NZ_CP006837.1|WP_025218485.1|349559_350447_+|helix-turn-helix-domain-containing-protein
MAFEYLAQYKTFDSVADMDKSVEDHMAVHYYDLTESERAIVYKLASHSLEHTGACHLKASTIADALEISTKTVYRSVKKLESLGIIEKVPGTKLNGIKGASIYRILPYVPSSVSQRMTADEASNDEVCRPQSENQPSNSFNLLSSKQANNIMSLGNELALQAEKKKEYMNEYQVMLFDFMNSLPLGDSLKDELHKVVLASQVQSAPDFIKAKNALFKIAMDIKEGTLTVANTLRAVFVGAYSKVVERSNNKLYKSSSIEETPYKERPVPFYNWLKERDTSTQTCSKPNLENWLEW
>NZ_CP006837.1|WP_137036932.1|348945_349158_-|helix-turn-helix-transcriptional-regulator
MMELTKKVKRLIVEMDLNATQLADKIGTSQSNLSQKMKNESYSVQDLIKIAEATNSKLEINFIMEDGTKI
>NZ_CP006837.1|WP_025218483.1|348325_348847_-|SHOCT-domain-containing-protein
MDTIAETIKFAGFGKKKAMAKQIQLFDDKLTDQGETLLAVCASVKGTKQLYVTDKRIILHEIKGIVSNDERSIPLSSISSINISNKLVYSKIEIVSTGNKAIIDDVPAHIALEIKAGIENLKTMAKTSSAPAAKEKKDMFDVADEIRELKDLLDDGILTQEEFDAKKKQLLGI
>NZ_CP006837.1|WP_025218482.1|347404_348307_-|hypothetical-protein
MITSTKIDDTPNIKYEKRLVLFIDILGFSNLVLGSASDHEKLLKIRDSLKVLERELKREKELQELLEKNQQTLRNSPHTAYWKNDKPYVNPGKIDYTQFSDSIIISKPYINAQSLISLISNVSLLQARFLQEGILFRGGLAYGDMYHKENLCFGPAFNRAYYLESKVAKYPRIVIDNDIISGQAQPTDWTKHEKFEFEALFQSSIDTSNPFSFKDTDSEGNDLYYVNFMLLNTFRSAKTKILEIFNGQKQGLDRLDKDEEKVYLKLDWLTSTIEKHMKAFEIADAKNKEFMRQIARKQGF
>NZ_CP006837.1|WP_025218481.1|346613_347282_+|M15-family-metallopeptidase
MTSVTTTCRDLAELLPSAQTACRLLFQECYKAGIKNIFITETYRSQERQKYLYAQGRTRPGQVVTWTLNSNHKSRLAWDIAVGPPQSLYDATTLSRVGAIAKKLGIEWGGTWTKAIDRPHFEVKANWKMPKGYKLEGQVIVPSNSKLKVQLIVEDKKEEITVVNTNWNPGSPAMKTETENFIAQAVKEGIIQESHLKDLQSGAMTTDRLVGLYITIQQRRNK
>NZ_CP006837.1|WP_025218488.1|353684_356708_-|response-regulator
MALRKPIVRHLLVILIIFIVLTIFRLLWLAYFTPSNNQPLAQAGVLDMRQQTLTEDEIYQINGEWLYYPEVLLKTPNSNETSSSIEQTVRKIPMQRGSATKQHFGTYRVKILLSANAHSNHRYAIRVPAISTASALYINGKLAGQSGVVSSNPSTHKGQVAPYTIYFTAEQSEIDVILHVSNFDTPSNMVIDKRLSFSSASAMMHHQFITQLSLVAISMLLILFALFSILVFLFIYRNKKVLLFTVGFLLPLADELITYDRSILDWLHLDYVWSLKLSNLIYLGASYFFVQFIRVLLVRYQQAKYFRWFTTLYALGALLIILLPIQWLHTANLAFFMLYVMSFLYVVVLALKEYIGNQESSAFIAFTAIGTTNGIIWGLIKMSFVLDIPFYPFDYLMIALGFAGYWFKRFYENQQQINLLVAKLQKDGEMKDEFLLSNAQKLWDPMNKMITLGQTIYDNPNNCFVMEDKQNLKYLIDIGRSMSFTLNDIVDYTRLKDNNLHLHKKNVRIQGVVSGVFDMLRFIAVGKQIQMTSSIARDFPLVLADEKRLIQILFNLLHSSIKNTNASSIEISATIERKMAVIYIKLTESGTNNPDINLHEHLFSSDKGLSDNEEIHLSFLISKQLIELHGGSLLNKGADLLFTIPIVDVMEEIEQLDDERTEDIHLQENNTQLKASATEKQFKILMVDDDPVNLTMMRSLFSATEYNITTITSSEKALDLLRLQRWDLVIIDAMLPYISGYALIENIRQHYTLLELPILLLTARNNPEDVYTGFAHGANDYVTKPINSLELKVRCRALIDLKYSINQQLHLETAWLQAQIQPHFLYNTLNTIASLSTIDPDRMIDLMHQFGKYLHASFDVKNLQRVVPLRHELELVRSYLYIEQQRFGELLQIDWDIDEQIDVEIPPISLQTLVENALRHGVLKQKGGGTVCIRIKELADYVTVSVIDNGIGMDATTLAQLLSDTDITSRGIGLRNTDLRLKRIYGQRLQIKSTPNEGTTITFHIPK
>NZ_CP006837.1|WP_174412981.1|357063_358029_+|GGDEF-domain-containing-protein
MVVLVTSSISIWISYKSYSEMLTQPNHALQEAFIEEVSDIAEIYVQESLQNSQTEFLVKDRLEQAVSQLQKESVVSVSVFLKKILLPLLLIVAIVFILVLWFVLKIIRPLQDIVKSGQEGCGINDLKLVNDWYAEASNLKDAMLKVKADSQNKIKELTDQLKLDSLTGIPNRRSMDQVLSNLIAEKVPHAIILIDLDEFKSVNDTYGHTVGDEVLKAFANKMKESVQGSCFRYGGEEFLIILPYTAIEDAVKLAEELRVKQAQAENPSGRPVTLSAGVTVFSSSICDPNQLIAIADQALYEAKQSGRNCIRVVEDFSRISS
>NZ_CP006837.1|WP_025218490.1|358081_359209_-|response-regulator
MIRVIIADDEPLALLNMEKKLKEFDSVEVVKAFSTIKDLLDEAPTLDYHVAFLDVEMPGMDGLQIAQILKEWKKNVCIVFVTAYRDYAVQAFEINSLDYLLKPISKSRLEMTINRIHELFQLEIAPPTRVQQNEYSLSIQCLGGFTVLHNKNIVHWRTVKTKELFAFLLSNLNSHVPRDTIIEALWAETEYKKARVQLHTTVSYLRTTLSALGYFNVLQYVNGCYILQLENFQSDVLELEHLLKHKEEFGELDIERAEAFIQNSHGEYMATLDYSWIHSKSNFIHNQITLLLNYLVEHYKATNNVEKMERTLLVMLDYNPYSDKIIQELLQLYIQEDNRANAVKVYKDFKKTLFTDLDISPNQETIELYATIAQE
>NZ_CP006837.1|WP_024364657.1|359755_360547_+|LysM-peptidoglycan-binding-domain-containing-protein
MKKKAIALAVALTLGMGMFGSTTSAKGVYTGQTSNILWGISPIYNLSLAELQQLDEFDSIWINPDQTLSMEKILEEEKTDDTHLIEAGDTLFSLAKVHNVKVDDLKEWNNLTSDLILVGETLAVKASAAKPKTAKTIAQKPATKQATTKTATTKQATTTASAPASQNGQTYTMRATAYTAYCKGCSGITANGTDIRSNPNLKVIAVDPRVIPLGTKVWVEGYGEAIAADTGGAIKGNKIDVFIPSDGQARNWGVRTVTVKILN
>NZ_CP006837.1|WP_024364655.1|361642_362200_+|superoxide-dismutase-family-protein
MKLTTLFIISLGVFLVGCADKDEKAEQQSVSDSSVALTATAKVMSSDNKSLGEAKFEEQADGVKVTVTVSGLPAGKHGMHIHEVGKCEGPDFGTAGGHFNPTQKEHGKDNPHGHHLGDLPNLEVAEDGTATMSVLAEGVTLQKDAEHSLMDGEGTALVIHENEDDHMTDPTGESGGRIACGVIQS
>NZ_CP006837.1|WP_025218491.1|362777_363344_+|superoxide-dismutase-family-protein
MKKISILIISLTVFVGGCNLFDKKDEKVTVNSNANSSLTATAKVIGSNNESYGNAFFEQEGNGVKVTLALSGLPAGTHGIHIHSVAKCEAPKFESAGSHFNPTNKEHGKLNPNGYHLGDLPNLEVGEDGTVDLNFLAEGVTLQKNAENSLMDGEGTSLVIHEAADDYKTDPAGNSGARIACGAIQSGS
>NZ_CP006837.1|WP_025218492.1|363770_364766_+|TAXI-family-TRAP-transporter-solute-binding-subunit
MKKKQFRLFMLLSAIALLILAACGSDSSTGSDKENGNGDTASSEKPKFLSLLTGGTQGTYYALGGTFADLITTETGIKTTAEVSQASAANMTALQEGKGEIAFVQTDIAYYATEGKFMFEGKKIDTIAALGALYPETVQLVTTEASGIKTYADLKGKKVSVGAPGSGTYANAEQLLEIHGLTMNDIKAQNLDFGESTDGLQSGQIDAAFITAGTPTGAVEALNATTKVNIIGVDAGKADELIAKYPYYAKDTVKAGTYGIANDTETVSVLAMLAVNKDLPEDVVYAMTKAIYSNTDKISHAKGAFIKAETALDGISIDIHPGAQKYFDENK
>NZ_CP006837.1|WP_025218493.1|364973_365489_+|DUF1850-domain-containing-protein
MRKRRIGLVIAVCCICLGIIIFLPLQKVFAFTETRVDDPIVHYIPLTSDEDFRIRYTHSIHKSDVLEYYRCIEEQRIQMIGMEYEDLAIGMPGYAEENQTLTQRDGKYFLQFDKEVIENFTIYIGDLDLDLVFVYKEQEYDLKKDLQRGKSYLFEVKRLSLYERWKGVRMK
>NZ_CP006837.1|WP_024362724.1|365485_367522_+|TRAP-transporter-permease
MTKQHERNTEVKEEFEQISAEAQQAILEKYDIESNVRTISGIMKHIIFFGLLAFSLFQLYTAIFGQFTAPIQRTIHLGFGLALIFLLFPARRKAPKHKIAWFDYILSLLSVVVGSYWALNYTELVNRNGTITQLDFIVGLIAVFLVLEAARRAVGLPITIIAVCFLIYAYFGPYFPAFMAHRGQDFESIVNLMFYTTDGILGTPISVSATFIFVFLLFGAFLVKTGVGQYFNDLAVAFAGKLIGGPAKVAVFSSALQGMISGSSVANVVTSGSYTIPMMKKLGYRKEFAGAVEAAASTGGQLMPPIMGAAAFLMVEFIGRGITYWDIAKAAAIPALLYFTGIWIMTHFEAKRVGLKGLRDDQMPNRKEVFKKIYLLLPIVSIIILMLTGTPVMHAALYGILISIAVAMFNKDTRLKPKDIIDALVEGARTALGVVAATACAGIIVGVVVKTGLGLSLANSLVALAGGSIILTLVFVMIASLILGMGAPTTANYVITSTIAAPAIVALLSPNTPQELVPVVVLLSAHFFVFYFGIIADITPPVALAAFAASGISGGDPIKTGVNSAKLAIAAFIIPYMIVFSPALLMIDTTIPQILWVVFTAVTGMVAIGAGVIGYWYRKVLWFERLIAIVAGLLLIYPEKFSDWAGLAIFIVLVVIQILTQHKYGGNGMDNDNKSVTA
>NZ_CP006837.1|WP_162832718.1|367758_367902_+|hypothetical-protein
MEQLLNSKFETYLMDQEAEFLTSNQNIEEQTNQLQYEEYPEGFFSSL

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Crispr_ID: NZ_CP006837_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006837_3

875566-875660

Orphan

Consensus_repeat	Method
AGTGCCAGTCACTCAAACAATTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006837_3

>merge|NZ_CP006837|3|875566-875660|CRISPRCasFinder
AGTGCCAGTCACTCAAACAATTTTGAATATTAAAAGGAAAACCCACGAGAAGTGGGTTTTTTACGTATTATTGGTGCCAGTCACTCAAACAATTT

>NZ_CP006837|3|2|875566-875660|CRISPRCasFinder
AGTGCCAGTCACTCAAACAATTT	TGAATATTAAAAGGAAAACCCACGAGAAGTGGGTTTTTTACGTATTATT
GGTGCCAGTCACTCAAACAATTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006837.1\|WP_024362214.1\|874146_874356_-\|DNA-dependent-RNA-polymerase-auxiliary-subunit-epsilon-family-protein	unknown	unknown	gnl\|CDD\|184224
NZ_CP006837.1\|WP_024362215.1\|872473_874141_-\|ribonuclease-J	unknown	unknown	gnl\|CDD\|223668
NZ_CP006837.1\|WP_025218731.1\|879951_881052_+\|2-aminoethylphosphonate--pyruvate-transaminase	unknown	unknown	gnl\|CDD\|184076
NZ_CP006837.1\|WP_025218730.1\|877325_878951_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|274495
NZ_CP006837.1\|WP_025218726.1\|864249_866772_+\|bifunctional-lysylphosphatidylglycerol-flippase/synthetase-MprF	unknown	unknown	gnl\|CDD\|225451
NZ_CP006837.1\|WP_024362205.1\|884164_885142_+\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP006837.1\|WP_024362223.1\|861114_861657_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380339
NZ_CP006837.1\|WP_029747190.1\|881041_881830_+\|phosphonoacetaldehyde-hydrolase	unknown	unknown	gnl\|CDD\|184075
NZ_CP006837.1\|WP_024362207.1\|882092_882650_-\|peptide-deformylase	unknown	unknown	gnl\|CDD\|234668
NZ_CP006837.1\|WP_024362211.1\|876580_877333_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP006837.1\|WP_024362206.1\|883045_884161_+\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|213783
NZ_CP006837.1\|WP_024362221.1\|862843_863296_+\|redoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|239310
NZ_CP006837.1\|WP_025218728.1\|867783_870873_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP006837.1\|WP_025218727.1\|867075_867573_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP006837.1\|WP_024362209.1\|878953_879937_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270262
NZ_CP006837.1\|WP_025218729.1\|870972_871806_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP006837.1\|WP_025218725.1\|862061_862604_+\|peroxiredoxin	unknown	unknown	gnl\|CDD\|239313
NZ_CP006837.1\|WP_025218732.1\|885189_886533_+\|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl\|CDD\|237001
NZ_CP006837.1\|WP_024362212.1\|875674_876433_-\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP006837.1\|WP_024362220.1\|863476_864139_+\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643

Protein	Function_ID	Function_description	E-value
NZ_CP006837.1\|WP_024362214.1\|874146_874356_-\|DNA-dependent-RNA-polymerase-auxiliary-subunit-epsilon-family-protein	gnl\|CDD\|184224	PRK13667, PRK13667, hypothetical protein; Provisional.	3.0842e-27
NZ_CP006837.1\|WP_024362215.1\|872473_874141_-\|ribonuclease-J	gnl\|CDD\|223668	COG0595, COG0595, mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair].	0
NZ_CP006837.1\|WP_025218731.1\|879951_881052_+\|2-aminoethylphosphonate--pyruvate-transaminase	gnl\|CDD\|184076	PRK13479, PRK13479, 2-aminoethylphosphonate--pyruvate transaminase; Provisional.	0
NZ_CP006837.1\|WP_025218730.1\|877325_878951_+\|ABC-transporter-permease-subunit	gnl\|CDD\|274495	TIGR03262, PhnU2, putative 2-aminoethylphosphonate ABC transporter, permease protein. [Transport and binding proteins, Amino acids, peptides and amines].	1.31356e-97
NZ_CP006837.1\|WP_025218726.1\|864249_866772_+\|bifunctional-lysylphosphatidylglycerol-flippase/synthetase-MprF	gnl\|CDD\|225451	COG2898, COG2898, Uncharacterized conserved protein [Function unknown].	2.90239e-140
NZ_CP006837.1\|WP_024362205.1\|884164_885142_+\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NZ_CP006837.1\|WP_024362223.1\|861114_861657_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.28369e-19
NZ_CP006837.1\|WP_029747190.1\|881041_881830_+\|phosphonoacetaldehyde-hydrolase	gnl\|CDD\|184075	PRK13478, PRK13478, phosphonoacetaldehyde hydrolase; Provisional.	2.20837e-151
NZ_CP006837.1\|WP_024362207.1\|882092_882650_-\|peptide-deformylase	gnl\|CDD\|234668	PRK00150, def, peptide deformylase; Reviewed.	2.98113e-66
NZ_CP006837.1\|WP_024362211.1\|876580_877333_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	2.06109e-103
NZ_CP006837.1\|WP_024362206.1\|883045_884161_+\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl\|CDD\|213783	TIGR03181, PDH_E1_alph_x, pyruvate dehydrogenase E1 component, alpha subunit. Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase].	0
NZ_CP006837.1\|WP_024362221.1\|862843_863296_+\|redoxin-domain-containing-protein	gnl\|CDD\|239310	cd03012, TlpA_like_DipZ_like, TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA family belong to this subfamily. TlpA is a disulfide reductase known to have a crucial role in the biogenesis of cytochrome aa3.	5.46747e-28
NZ_CP006837.1\|WP_025218728.1\|867783_870873_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP006837.1\|WP_025218727.1\|867075_867573_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.46124e-31
NZ_CP006837.1\|WP_024362209.1\|878953_879937_+\|extracellular-solute-binding-protein	gnl\|CDD\|270262	cd13544, PBP2_Fbp_like_1, Substrate binding domain of a putative ferric iron transporter, a member of the type 2 periplasmic binding fold superfamily. The substrate domain of this group shows a high homology to the periplasmic component of ferric iron transporter (Fbp), but its biochemical characterization has not been performed. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	5.00727e-35
NZ_CP006837.1\|WP_025218729.1\|870972_871806_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.646e-15
NZ_CP006837.1\|WP_025218725.1\|862061_862604_+\|peroxiredoxin	gnl\|CDD\|239313	cd03015, PRX_Typ2cys, Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. The functional unit of typical 2-cys PRX is a homodimer. A unique intermolecular redox-active disulfide center is utilized for its activity. Upon reaction with peroxides, its peroxidatic cysteine is oxidized into a sulfenic acid intermediate which is resolved by bonding with the resolving cysteine from the other subunit of the homodimer. This intermolecular disulfide bond is then reduced by thioredoxin, tryparedoxin or AhpF. Typical 2-cys PRXs, like 1-cys PRXs, form decamers which are stabilized by reduction of the active site cysteine. Typical 2-cys PRX interacts through beta strands at one edge of the monomer (B-type interface) to form the functional homodimer, and uses an A-type interface (similar to the dimeric interface in atypical 2-cys PRX and PRX5) at the opposite end of the monomer to form the stable decameric (pentamer of dimers) structure.	4.29594e-108
NZ_CP006837.1\|WP_025218732.1\|885189_886533_+\|2-oxo-acid-dehydrogenase-subunit-E2	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	0
NZ_CP006837.1\|WP_024362212.1\|875674_876433_-\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	3.2316e-74
NZ_CP006837.1\|WP_024362220.1\|863476_864139_+\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	3.8328e-59

>NZ_CP006837.1|WP_024362214.1|874146_874356_-|DNA-dependent-RNA-polymerase-auxiliary-subunit-epsilon-family-protein
MIYKVYYQEKANEIPVRENTKSLYLEAASEREVRQKLQDRHYNIEFIQLLEGNYLEYEQASPNFVLEEI
>NZ_CP006837.1|WP_024362215.1|872473_874141_-|ribonuclease-J
MKFVKNDQAAVFALGGLGEIGKNTYGVQFQDEIILIDAGIKFPEDDLLGIDYVIPDYTYLVRNVDKIKGLFITHGHEDHIGGIPYLLRQVNVPVYGGKLALGLLRNKLEEHGLLRTTKLIEIKEEDIIKFRKTSVSFFRTTHSIPDAYGIVVKTPPGNIVHTGDFKFDFTPVGEPANLTKMAEIGRDGVLCLLSDSTNAEKPNFTMSERTVGKSIDEIFRKVDSRIIFATFASNIHRLQQATDAAIKYGRKIAVFGRSMDNAITIGRELGYINAPKDTFIDAQSINRLPANEVMILCTGSQGEPMAALSRIANGTHRQIQIQPGDTVVFSSSPVPGNTVSVNKIINLLFRAGAEVIHGALNNIHTSGHGSQEEQKLMLRLMKPKFFMPIHGEFRMLKMHTHLAEDCDVPLENTFVMENGDVLALSANEAHVAGRIPSGDVYIDGNGIGDIGNIVLRDRRILSEEGLVIVVVSVDMENQKIVSGPDIISRGFVYMRESGTMINEAQKMLNRHLNETIQGKTPQWTELKNEITDVLGPYLFEKTKRRPMILPIIMEV
>NZ_CP006837.1|WP_025218729.1|870972_871806_+|TetR/AcrR-family-transcriptional-regulator
MLKKQLIMEKALELFSEQGFEATSVQQITERCGISKGAFYLSFKTKDELLFSMVDYYLQQFIADIDHVVRNSNKKDVMLVDFYKNIFQAFKKHAASSRVFFNEKVFLTNKELFLKVSAYEADMSKSIVQMLEQLYQEELQETKYDVMYCVKGFMKSYAELFIFSDLPLDLDQLAQSLAEKTDIIARHTTIPFITEELAQLVARPCDQEITQESLLQLIDQSIHNLEPSIERESLELLKNQVEHTTYSQAIIKGLIENIRLQPGCQWVVYVLDKYFQF
>NZ_CP006837.1|WP_025218728.1|867783_870873_-|efflux-RND-transporter-permease-subunit
MKGLVNFVLKNKLAVWLLTIIITVSGIYSGTRMKMESIPDISIPYLIVMGVYPGATPEQVMNELSIPFEKSIESLEDVKAVYSTSSSNVAQVQVEYDYGIDMDEKKRQLESALDNVKLPEGAQEPTIMAISMNMMPVVALSVSSSKEDIVDLTSTVEDLLLPKIEKIDGVASATITGQHIEEVSFKYDEEKMAALGLTEDAVKQMIQASDMSLSLGLYQFTVGEQAVSVDGKVKSIDELKDLLIPVTPSATQPSPFVRLGDIATIEVEGKVQSVSRTNGKDAIAIQIVKSQDANTVTVVNAVKELIKDEEKRIDGLKIDISLDQGAPIEDSVFTMIEKAVFGGAIAVLIILLFLRDFKSTIISIISIPVSVFMALLLLNWMDITLNIMTLGAITVAIGRVIDDSIVVVENIYRRIHLKQEKLTGRALIREATIEMFKPILSSTLVTVAVFAPLMFVGGMVGELFMPFALTMTFALGASLIVAITIVPALSHFLFRKKIYGEKKESQHQEVGKLANWYRGILEKALNHKIITSTIAILMLVGSLALTPLIGFSFMGSQEEKVMYLTYTPGTGELADETEVNVAQVEKELMKRKDIDILQVSITDATNADPAAMMMGGTAGGALMYLIFDPEMEDFPAARQEVEDYVFNLDQSGEWKSQNFSSTSMASNEVSYTLYSEDLNKLRSAVKDVEGSLKEVKGLEDVKSDYEDPYVEHVLKVEQKNVLQYGLTTAQIVMALNSTASQEVLTTVERDGKDINVIVKRDAKAAALSIDDVLKTEIKTALGTTMTIGELVNVEEGTTLNSLSRSKGEYFATVSATIIGDDISKATTAADKKIDKLDLPKGVTTGVSGVAADMQETFTQLGIAMLAAIAIVYFILVVTFGEGLAPFAILFSLPFAVIGAFVGLYVTNQTISVSVMMGLLMLIGIVVTNAIVLVDRIIHMERDGLGMREAILEAGATRLRPILMTAIATIGAMIPMAIGNGGSGLISKDLAITVIGGLLSSTLLTLVVVPIVYEMLSKMLKKNRKDVEEN
>NZ_CP006837.1|WP_025218727.1|867075_867573_+|GNAT-family-N-acetyltransferase
MLITENCVIESLKPHHQDDIYSLYCNQDVRAFLGGIPDKNYILSSFNSMLQSSFPNSYFTISLKNTNDFIGLVSIDEYHEQTTYELSYQFLPQYWGKGYAQEVLTAVIHYGFTSLQLSKLVAETQTANIASCRVLEKIGMEKIQVLERFGQEQAVYQLLSTNNGC
>NZ_CP006837.1|WP_025218726.1|864249_866772_+|bifunctional-lysylphosphatidylglycerol-flippase/synthetase-MprF
MFKFRKEPLLRFLKIIFPIILLAIAIYEIQQSLRGVNVNLLRNEVSQLQVWELLLIFFITFCAITPMIFYDVILVKLLGMKINKRTLVNNSFIVNTFSNLIGFGGLVGVFLRNYFYSKYKVDREGLLKSIATVTLFYLTGISLLTWLMYLFFWDFPMLKEIRWLSIAVIVVSLYVPVFLVTHLIRYNKRSALTYKVFLQLMITSVAEWLAVFFVIWMLTIIIQIPMELSTLIPIFLIASCAGIVSMIPGGVGSFDLVFLWGTQSVGIAEEKVLFLLILYRVGYFVLPFLVSVLLFMKDYWERWNRSWDDVPNVIFQKISHMLLTSLVFISGIVLLLSASVPGILSRLKIAQEFLSSPIMNISHQLTVAAGFILLGLCRGIKYKVKTAYQLAIIVLSSSALFSISKGFDYEEAIFLLIVAVLLMASKKQFYRESYVLTWGTILFDLAAVIFITAMYLLIGYINLPTAKIHIPTPLQYYILTDYRDLFFSAMIGILIACSIFYLGYLTRGPKKMYKLLSKEHEDKIKSHLMEYTGTEFSHLIFLHDKFVYWNKENTVLFAYQIYADKIVVLGDPVGPESDLLSAIQEFLEVADRHGYTPVFYEINNKIFPVLHEHGYSFFKLGEEAFVDLEMFTFAGKEMKGSRAVKNRFERENYTVTILSPPYSQEVMTELAEVSRRWLQGRAEKGFSLGFFDENYLNTSKIAVLRGAEGVIGFASIMPMYDNGERISVDLMRFKPGAPSGTMDFIFLSLFQWAKEQGYRVFNMGMSPLSNVGQSRYSFLSEKIAAQIFLHGQYFYHFKGLKNFKLKYADFWEPKYVAYRKKSSLPFTMAQITLLIGRKRK
>NZ_CP006837.1|WP_024362220.1|863476_864139_+|TrkA-family-potassium-uptake-protein
MKKEFAVIGLGRFGGSIVRELMSQGAQVMAIDHSSERVDEFAAIATQAVIADSTDESVLNSLGIRNFEHVIVAIGEDIQASILTTIILKEIGVQQITVKAQNDYHEKVLRKIGADFVVHPERDMGIRIANNMLSNTVLDYLELSDEHSIMELKANDAIAGYSIMDLDIRAKYGINIVGIKRGSDIIVSPQASDKILLGDIMLLIGADVDINRFVKKAMKE
>NZ_CP006837.1|WP_024362221.1|862843_863296_+|redoxin-domain-containing-protein
MKLREQMPELTGATTWLNGEVTKAQLVGEKPTLIHFWSVSCHLCKEAMPEVNNFRDQYKDELNVIAVHMPRSEADTDLDTIKAVAAEHDITQPIFVDNEMKLTDAFENQYVPAYFVFDKDGQLRHMQAGGSGMKMLEKRVNRVLDEMRNA
>NZ_CP006837.1|WP_025218725.1|862061_862604_+|peroxiredoxin
MAERMVGKQAPDFTMEAVLPDKSFGKVSLEEIKAQDKWTVLFFYPMDFTFVCPTEITAMSDRYDEFEDLDAEVIGVSTDTIHTHLAWINTDRTQNGLGELKYPLAADTNHAISKEYGVLIEEEGIALRGLFIINPEGELKYQTVFDNNIGRDVDETLRVLQALQTGGLCPANWRPGQATL
>NZ_CP006837.1|WP_024362223.1|861114_861657_-|helix-turn-helix-transcriptional-regulator
MQIGGKIKALRLKKGLTQEELGERTDLSKGYISQLERDLNSPSIETLFSLLEVLGSTPKEFFDDDAPEQKVVYTEEDQSTYTDEEKKYEIQWLIPTSNEKEMEPIFLTLAADGEFKQFEPSLSETFIYIVKGRIRLVLGNEQYIASEGNALYFDAADHHQIFNAHDDETKILLVATDSYL
>NZ_CP006837.1|WP_024362212.1|875674_876433_-|DeoR/GlpR-transcriptional-regulator
MYTVERQQHILQFIRNNKVVKLVTLTKEFNVSMETIRRDIQQLVQEKKIEKFYGGVKYIEPVEGLMDNRLTQQLTEKIAIAKACASLVNNGDCIFIDSGSTTYQMTPFLLGKEKLTVVTNSLPVAFDLIGSNIEVMIIGGRVRHSEKSVTSNDFLFHFDHLNINKAFICASGVTLEKGISDFSLEEAMTRKQLINISQTVYVATDSTKFNKDVAIQVCPLEEVDMILTDNGLPKETLHQFTEAGIQLKVVDI
>NZ_CP006837.1|WP_024362211.1|876580_877333_+|ABC-transporter-ATP-binding-protein
MLELKNISKSYKNKNVLRDINLTIDSGEIVSLLGPSGCGKTTLLNIVLGLTEQTDGQLFYNGQDISKQSMQDRGFNIVFQDFALFPHLNAYDNIVYGLKNKKQQMSKAEIQEYVDFLELAPHLHKKIHELSGGQKQRVSIARTLVMQPKILLLDEPLSALDGVIKESIKERIKSIARQFKLTTIIVTHDPEEALTLSDKVLIINEGTVSQYGTPHEILKTPKNQFVEDFILKQLHIKRHNIYQLFGESYA
>NZ_CP006837.1|WP_025218730.1|877325_878951_+|ABC-transporter-permease-subunit
MLKTNKMVKILFLPIVFFFLFFLIVPLLYMFWQSLKKGNSVTIQNYVEALQSVEIREAFLNSFQVSFVAAVITTCLAFALAYAMHFTTMNQHLKKLVHIGVTLPMLLPTITYGFVLLYTFGNQGILTKLLGKPLVTIYGFNGLLIGYVLYTLPVAFILMQNSMQYIDKRFLLVSMLMHDRPSRRFYHTVFRPMIGTIGGAFILTFILSFTDFGIPASVGGGYKVIATELYQAMLGSIVRFEQGAVISVLMLVPAVLGIVMLSVLDRFNFQYKHVSQSALVVHRLRDSTFTVLSLVCVSTIFIIFSTMFIVPFTKGYPYDFSFTLEHVQNVLAEKNLTRVYMNSLIVAFFTAILGVGIAFVSALLNVRTPLKGRSTLDFASMITNTVPGMVLGLSYLFFFNGSSLKGTFFIIIAYTVVHFFTTPYLMAKNSLQKMDPTWEVTGELLKDSWLQTVVRVILPNIRPTIFQMFSYYFLNAMVTVSGVIFLVSTKTMLVSTRIKELQHFAKYTDIFVLSIFILCTNLIVKLGCDYITTNKEKFKEM
>NZ_CP006837.1|WP_024362209.1|878953_879937_+|extracellular-solute-binding-protein
MKKSTVMMFGTVSSAIVLAACGGAEADTKDQVIIYSNADDEAIEVMQTTLDKKGYEGKYIIQSFGTSELGGKMMAEGKDIEADVVTMASYFIESAQTSKSMFVELTSELKPLDGGSTYALPILGNVGSIFINTDLLAQKGLPVPQTIKDLTKPEYKDLVSFPNILDSSTGWLLVQAIMSEYGEKEGKQVLADLIKNAGPHIESSGSGPIKKVKTGEVAAGFGLRIQAIDAKNEGLPIDYIDPTEGNFTLTESVAVVDKEGDEALASEIAKVIATEARADLLKQYPVALYEGEQVEEKYVPKYLKKWDTTLTVDLLEKHQTFFKEAQQ
>NZ_CP006837.1|WP_025218731.1|879951_881052_+|2-aminoethylphosphonate--pyruvate-transaminase
MNTYKLLTPGPLTTTEAVKKEMLVDRCTWDDDYKQVTQEIRKQLVAIAQVDETDYTAILMQGSGSFVVESVLTTAIGNADKVLIITNGAYGERIVEMATVLQLQHVVYSLPYHEQPSPLEVQAILEKDAAITHVAIVHCETTTGILNPIDEIGKVVKSFNKTFIVDAMSSFGGVPMDLSNMQIDFLISSANKCIQGVPGFGFVVAKIEALEKCKGQAKSVALDLYKQWEVMSVDGKWRFTSPTHVVAAFAKALEELAEEGGVAARYTRYAKNNQLLRERLSRCGFEAYISAEMQSPIITTFLYPYEGFSFEHFYHEMKQAGFVIYPGKLTEFDTFRIGNIGDVHEEDMTTLCNVIENYMAVKNNEN
>NZ_CP006837.1|WP_029747190.1|881041_881830_+|phosphonoacetaldehyde-hydrolase
MKIEAVIFDWAGTAVDFGCFAPVNVFLTIFEDAGVAVTLEEARKPMGMLKIDHIRTMLEMPRVSEAWARVYGRSFTEQDVQALYSQFETKLMASLAKYTDPIPHVKETVQQLRQAGIRIGSTTGYTAAMMEVVTHHAAEKGYKPDFLVTPTDIGDKGRPYPYMIFRNLEELGVKATKQVVKVGDTTSDIQEALNAGVWAVGVIVGSSEMGLTEQEFMSLSDEEQQAVIEKTKAIFEQTGAHYTIQTMRELPALIETINARLV
>NZ_CP006837.1|WP_024362207.1|882092_882650_-|peptide-deformylase
MILMDDIIREGHPTLRTKTEEVQFPLTDEIKQLATDMLQFLINSQDPEIADKYDLRSGIGLAANQVNSLHRMFALHLKDDKGEQLSFIAINPKIVSHSVENTYLPTGEGCLSVDRNVPGYVPRHARITVKFKTMDGEEKKMRLTGLPAIAFQHELDHLNGIMFYDRINEKNPFAEIPDAVPYERD
>NZ_CP006837.1|WP_024362206.1|883045_884161_+|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MSKKNNNIFDPQQTLTEIEEKFEMFQILNEEGEIINEEADPKLADEELVELMTRMVYTRILDQRSISLNRQGRLGFYAPTAGQEASQLASHFALEKEDWILPGYRDVPQIVWHGLPLDKAFLFSRGHFEGNQIPEGVNVLPPQIIIGAQFIQAAGVALGMQKRGKKAVAVTYTGDGGSSQGDFYEGMNFAGAFKSPAIFIVQNNQFAISTPRELQTAAKTIAQKGVAAGIPSILVDGMDALAVYVATRDARERAINGEGPTFIETMCYRYGPHTMAGDDPTRYRTSDTDNEWAQKDPLVRFRKYLEGKGLWDEKKEEAVIERAKEEIKDAIKKADAAPKQKVTQLMENMYKGEMPSNLKEQYEIYKEKESK
>NZ_CP006837.1|WP_024362205.1|884164_885142_+|alpha-ketoacid-dehydrogenase-subunit-beta
MAQMTMIQAITDALRTELKNDENVLLFGEDIGVNGGVFRATEGLQKEFGVDRVFDTPLAESGIGGLAIGLSLQGFRPVPEIQFFGFVYEVMDSISGQLARLSYRSGGVYNAPVTIRSPFGGGVHTPEMHSDSLESLMTAQPGLTVVVPSTPYDAKGLLISSIRNDNPVIFLEHLKLYRSFREEVPEEAYEIPLGKADVKREGKDLTIIAYGLMVHESLKAAEELEKEGHSVEVIDLRTIQPIDIETIIASVEKTGRAIVVQEAQKQAGIAANVVAEITERAILSLEAPVLRVAAPDTVYPFPQAEGVWLPNYKDVMETAKKVLTF
>NZ_CP006837.1|WP_025218732.1|885189_886533_+|2-oxo-acid-dehydrogenase-subunit-E2
MAFEFRLPDIGEGIHEGEIVKWFVKAGDTVKEDDILCEVQNDKAVVEIPSPVEGKVEEILVGEGTVAVVGDVLIRLDAPGYEDLKLKGDDHAEAKTEAQVQSTAEAGQDVAKAPAKEEAPKAPATAEVAVKQETADSTKRIIAMPSVRKFARDNEVNIHEVSGTGKNGRILKEDIENFLNGGGSVQAAEAPVANEEAVAQQETAQAAPVVLEGDFPETREKMSGIRKAIAKAMVHSKQTAPHVTLMDEVDVTALVAHRKKFKDIAAEKGVKLTYLPYVVKALISTLREFPEFNRSLDDATQEIIQKHYYNIGIAADTEKGLLVPVIKHADRKSVFAVSNEINDLATKARDGKLAPHEMKGASMSITNIGSAGGQWFTPVINHPEVAILGIGRISEKPVIKNGEIVAAPVLALSLSFDHRMIDGATAQNALNHLKRLLSEPELLLMEA

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Crispr_ID: NZ_CP006837_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006837_4

1779389-1779485

Orphan

Consensus_repeat	Method
ATGAATCGTCCAATTTAAAAATCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP006837_4

>merge|NZ_CP006837|4|1779389-1779485|CRISPRCasFinder
ATGAATCGTCCAATTTAAAAATCGCTCATTTTAATGAATGGTATTTCGTTAAAAATGGGGGAGGCAAGTTTCATGAATCGTCCAATTTAAAATCGCC

>NZ_CP006837|4|3|1779389-1779485|CRISPRCasFinder
ATGAATCGTCCAATTTAAAAATCGC	TCATTTTAATGAATGGTATTTCGTTAAAAATGGGGGAGGCAAGTTTC
ATGAATCGTCCAATTTAAAATCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006837.1\|WP_024363420.1\|1783930_1784665_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|379263
NZ_CP006837.1\|WP_024363418.1\|1782257_1782746_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|183256
NZ_CP006837.1\|WP_025219186.1\|1780792_1782040_-\|ferric-reductase-like-transmembrane-domain-containing-protein	unknown	unknown	gnl\|CDD\|226582
NZ_CP006837.1\|WP_025219188.1\|1786005_1788486_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225461
NZ_CP006837.1\|WP_025219183.1\|1776419_1777121_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|370378
NZ_CP006837.1\|WP_162832722.1\|1788935_1789076_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006837.1\|WP_024363410.1\|1772920_1774294_-\|NADP-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|181834
NZ_CP006837.1\|WP_024363415.1\|1778589_1779078_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006837.1\|WP_025219189.1\|1789240_1789567_+\|YqzG/YhdC-family-protein	unknown	unknown	gnl\|CDD\|372435
NZ_CP006837.1\|WP_025219180.1\|1771165_1771819_-\|YIP1-family-protein	unknown	unknown	gnl\|CDD\|377418
NZ_CP006837.1\|WP_025219184.1\|1777209_1778382_-\|alanine--glyoxylate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223153
NZ_CP006837.1\|WP_025219182.1\|1774944_1776267_+\|D-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|235096
NZ_CP006837.1\|WP_024363423.1\|1788694_1788919_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006837.1\|WP_024363407.1\|1769902_1771105_+\|malate-dehydrogenase	unknown	unknown	gnl\|CDD\|235976
NZ_CP006837.1\|WP_025219181.1\|1771990_1772677_-\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl\|CDD\|133470
NZ_CP006837.1\|WP_025219185.1\|1779527_1780733_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP006837.1\|WP_025219179.1\|1768408_1769233_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293807
NZ_CP006837.1\|WP_024363421.1\|1785107_1785944_+\|type-II-pantothenate-kinase	unknown	unknown	gnl\|CDD\|237346
NZ_CP006837.1\|WP_024363411.1\|1774481_1774955_+\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
NZ_CP006837.1\|WP_038510243.1\|1782842_1783631_-\|squalene/phytoene-synthase-family-protein	unknown	unknown	gnl\|CDD\|224478

Protein	Function_ID	Function_description	E-value
NZ_CP006837.1\|WP_024363420.1\|1783930_1784665_+\|SDR-family-oxidoreductase	gnl\|CDD\|379263	pfam13561, adh_short_C2, Enoyl-(Acyl carrier protein) reductase.	4.40473e-82
NZ_CP006837.1\|WP_025219188.1\|1786005_1788486_-\|hypothetical-protein	gnl\|CDD\|225461	COG2909, MalT, ATP-dependent transcriptional regulator [Transcription].	2.10749e-77
NZ_CP006837.1\|WP_025219186.1\|1780792_1782040_-\|ferric-reductase-like-transmembrane-domain-containing-protein	gnl\|CDD\|226582	COG4097, COG4097, Predicted ferric reductase [Inorganic ion transport and metabolism].	8.08955e-100
NZ_CP006837.1\|WP_025219183.1\|1776419_1777121_+\|DUF1963-domain-containing-protein	gnl\|CDD\|370378	pfam09234, DUF1963, Domain of unknown function (DUF1963). This domain is found in a set of hypothetical bacterial proteins. Its exact function has not, as yet, been described.	1.02357e-45
NZ_CP006837.1\|WP_024363410.1\|1772920_1774294_-\|NADP-specific-glutamate-dehydrogenase	gnl\|CDD\|181834	PRK09414, PRK09414, NADP-specific glutamate dehydrogenase.	0
NZ_CP006837.1\|WP_024363418.1\|1782257_1782746_+\|metal-dependent-hydrolase	gnl\|CDD\|183256	PRK11648, PRK11648, metal-dependent hydrolase.	9.97796e-25
NZ_CP006837.1\|WP_025219189.1\|1789240_1789567_+\|YqzG/YhdC-family-protein	gnl\|CDD\|372435	pfam13028, DUF3889, Protein of unknown function (DUF3889). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 110 amino acids in length. There are two completely conserved residues (A and Y) that may be functionally important.	5.58017e-36
NZ_CP006837.1\|WP_025219180.1\|1771165_1771819_-\|YIP1-family-protein	gnl\|CDD\|377418	pfam04893, Yip1, Yip1 domain. The Yip1 integral membrane domain contains four transmembrane alpha helices. The domain is characterized by the motifs DLYGP and GY. The Yip1 protein is a golgi protein involved in vesicular transport that interacts with GTPases.	5.31769e-05
NZ_CP006837.1\|WP_025219184.1\|1777209_1778382_-\|alanine--glyoxylate-aminotransferase-family-protein	gnl\|CDD\|223153	COG0075, COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism].	1.46278e-141
NZ_CP006837.1\|WP_025219182.1\|1774944_1776267_+\|D-serine-ammonia-lyase	gnl\|CDD\|235096	PRK02991, PRK02991, D-serine dehydratase; Provisional.	0
NZ_CP006837.1\|WP_024363407.1\|1769902_1771105_+\|malate-dehydrogenase	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NZ_CP006837.1\|WP_025219181.1\|1771990_1772677_-\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl\|CDD\|133470	cd01415, SAICAR_synt_PurC, bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase. A subfamily of SAICAR synthetases represented by the Thermotoga maritima (Tm) enzyme and E. coli PurC. SAICAR synthetase catalyzes the seventh step of the de novo biosynthesis of purine nucleotides (also reported as eighth step). It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.	4.3142e-48
NZ_CP006837.1\|WP_025219185.1\|1779527_1780733_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.01591e-40
NZ_CP006837.1\|WP_025219179.1\|1768408_1769233_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293807	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain. This subgroup includes the uncharacterized Bacillus subtilis yflN protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	3.1561e-26
NZ_CP006837.1\|WP_024363421.1\|1785107_1785944_+\|type-II-pantothenate-kinase	gnl\|CDD\|237346	PRK13317, PRK13317, pantothenate kinase; Provisional.	3.09373e-127
NZ_CP006837.1\|WP_024363411.1\|1774481_1774955_+\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	2.72539e-53
NZ_CP006837.1\|WP_038510243.1\|1782842_1783631_-\|squalene/phytoene-synthase-family-protein	gnl\|CDD\|224478	COG1562, ERG9, Phytoene/squalene synthetase [Lipid metabolism].	1.09277e-29

>NZ_CP006837.1|WP_024363415.1|1778589_1779078_-|hypothetical-protein
MNYYDPYYSDYDAVFGGFMVVFFFVLLGMLIVGYVVNALIYFMASKTNGFSDVAYIAWIPIINIYSLFLLTANGDDDATIRATAKKTTFIYAALFIISFVPLVGFIASLVMFGYWVYYTYRLLFRWTGESGKAVLYIILSIITCGLFYAIYGLMRMKRPFIV
>NZ_CP006837.1|WP_025219184.1|1777209_1778382_-|alanine--glyoxylate-aminotransferase-family-protein
MYENILRHPGPTPIPKKVQLAMNRDIFSHRSNEFVELYRETTELVKAVFGTKQDILLLPSGGTAALEATAVNTVNAGDDVVVITVGAFGDYFVSICEKYGFNVHKLAKQWGQACTAEELRTFLQPLQHIKAVFITYNETSTGILNPIAALAQVVREESDALVIVDGVSCIGGAPAEMDAWGIDILVTGSQKAMMLPPGLSLVSVSDRAWKVIEENTMPSYYLNLLSYRDWAHKGMTPNTPTITLIYGLREVCKLIEEEGGFAHTVARHELMKNMVRSAMKALHMELLTTDEFASPTITAIMAPKGIALNAFLHHLKQHYHLDFAGGLGPLQGEIFRFGHMGYCFPSDILQAVSLMEAALQDFAYDFEPGAGVSAAHKVFLAAQANTITSP
>NZ_CP006837.1|WP_025219183.1|1776419_1777121_+|DUF1963-domain-containing-protein
MKDSLKQAIILQAVEESVTYTDSKLGGRPYCKLGDDFPVHSSGIPYMFIAQLNFAKLPKLKDYPQQGLLQFFVLADEDYGVDKDGYYCRYYSDFDPSHDIEPFSDEEMEYELCEPIIFGGPYALKATLLQELVPYTDPRSVHYDLPIENPAYSKYFDETDGSGTKIGGYAFMDKNSFDEKNSNAELLFQLDMEGNAKKTYAMIADSGTLQFFIERDSLIAKDFTQLYYYLYSL
>NZ_CP006837.1|WP_025219182.1|1774944_1776267_+|D-serine-ammonia-lyase
MENDLKHELFHQYPLLETIKNRETVFWENTKWTKKAKTTLFSNEEVKDAEETLQRFSSYLIIAYPELLHSKGLIESPIQQIAQMKKALERMFALSIPGKFVLKCDHTLPISGSIKARGGIYEVLKHAERLAIANGMLTIEDDYAVFATEELRTFFQQYTIAVGSTGNLGLSIGIMAKKLGFNVVVHMSSDAKEWKKALLREKGATVIEYKADYSVAVEQGRLEASQNPMCHFIDDENSKDLFAGYAVAAKRLKVQLEKTNIQVDKAHPLFVYLPCGVGGGPGGVAYGLREIFGEHVHIFFAEPTASPCMMIGLMTGLHDEISVEDIGLDNQTEADGLAVGRASKFVGKVMESYISGCYTVKDEELFMSLALAMESEGVFLEPSAHAGMFGPIHLLKNGQNYIEMHHLQDKMEQATHLVWATGGSMVPQEMREQYMAKVNM
>NZ_CP006837.1|WP_024363411.1|1774481_1774955_+|YaiI/YqxD-family-protein
MKVLIDADACPVVDLALSISSEFEIETILFCDTSHRIERDNVITIIVPKGPDSVDFTLVNALSKHDIVITQDYGLAAMVLARGGYPIDQNGREMSNENIERLLDMRHVGQKIRRAGGRTKGPKKRTKENNMLFEMKFRQICERAILAQKMEESADGK
>NZ_CP006837.1|WP_024363410.1|1772920_1774294_-|NADP-specific-glutamate-dehydrogenase
MTTTTLSNEQLAQEYVDGVFEQLKQQNSHQAEFLQAAEEIFLSLVPVFAQHPEYIKANILSRIVEPDRIISFRVAWQDDNNQVQVNRGYRVQYSNVMGPYKGGLRFHPSVNESIIKFLGFEQIFKNALTGQPIGGGKGGSNFNPKGKSDSEIMRFCQAFMTELYRHIGPDVDVPAGDIGVGAREVGYLWGQYKRLTKANESGVLTGKTPGYGGSLARKEATGYGTVYFVEEMLKDANDSFEGKTVVVSGSGNVSTYAIEKAQAYGAKVVACSDSSGYIYDPEGLDLDAVKEIKEVKGDRISTYVNYRPNATFTEGCTGIWSIPCDIALPCATQNEINGDAARTLISNGVKAIGEGANMPSDLEAINEFLNAGVLFGPAKAANAGGVAVSALEMAQDSSRVFWSFEEVDAKLHQIMKNIYADSKAAADKYGYPGNLVVGANIAGFIKVADGMLSEGVY
>NZ_CP006837.1|WP_025219181.1|1771990_1772677_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MELLYTGKTKNVFKLEDGHYLLKFKDDVTGENGVFDPGANTVGLTIDGAGLAGLRLTSYFYSKLNEQGVPTHYVDANFDDATMTVKPATVFGKGLEVICRFKAVGSFLRRYGAYVQEGQPLDSFVEVTIKDDDRLDPPISEDALAMLNLLTHEEYAILKQRTIEISKFVGAELAKKGLTLYDIKLEFGRDAQTNEILLIDEISGGNMRAYKGEQYIEPLELEKIMLAD
>NZ_CP006837.1|WP_025219180.1|1771165_1771819_-|YIP1-family-protein
MENYNETPQQERSKVNPFLSTWMHPKQTARYMIDAKSIGYAILVMSIAYIGAMLTGLIDSNFLLDVSPWIIVLFCVILAPISAIIGTAFSTLILWLVGKLFKGSATFSEMFKGLSLAGVPFIALIPFYLIWLFTSPESLMDANYMESAPWIFWPSILMTAVTSIWSMVITVGVVAEAHRFSNWKAFFTVLIPSVVSIIIIFILVIIIFIGIIGISMI
>NZ_CP006837.1|WP_024363407.1|1769902_1771105_+|malate-dehydrogenase
MDIMKKALDMHAQYSGKLEVISKVPVQDSYDLSLAYSPGVAAPCIEIEKNPSLVYDYTMKGNMVAIVSDGTAVLGLGDIGPKAALPVMEGKAILLKRFANVDAFPLCLDTKSTDEIVSIVKALAPTFGGVNLEDISAPRCFEIEDRLRQECDIPVFHDDQHGTAIVVGAGMINANRIVKKDVATMKVVINGAGAAGIAILRILVQMGYKNIYMCDTKGIIYEGRAEGMNPIKDAVAHLTNPEKLHGTLDDALVGADVFIGVSVANLLTEAHIASMNENPVVFALANPNPEITYENAKAWGVRIMGTGRSDYPNQINNVLAFPGIFRGALDVRATDINEDMKLAAVEAIASLVSDEELTEEYIVPKSLDERVVEIVSRAVSGAAVASGVSELFQQQTVLSV
>NZ_CP006837.1|WP_025219179.1|1768408_1769233_+|MBL-fold-metallo-hydrolase
MYKLEKSIEIEQHGNVQCAHGKVAVQGIGMSVYSFYVDGLLIDTGSNSLAEEFQSFFRELSVEQVALTHAHEDHSGNAAWIQQQQKIPIYVHRESIANCAEDGNYPFYRQALWGQRPAFIAQPFGDTLETKSATWDIITTPGHTTDHLSFYNRATGAMFTGDLYIQTKTKDVLDEENIVHTLASLKKLLHFDFEQVYCCHAGFLADGRAKISEKIAYLEDLEGEVRKLYSQGYTDDAITKAIFRREYPITKVSGEQWSSKHIITAFTKQFKQES
>NZ_CP006837.1|WP_025219185.1|1779527_1780733_+|MFS-transporter
MNLGRNFWLLLVGQSLANIGDVLYIVSVIHIIYLLTGSAIAASFVPFTIATSMFVSSILTPLLFEKVNLKWLMAGSQIGKTCLLFALGLLLVSISTTNFYLLFIVISMIAFLDGCANPIRQTLVPHYVKDEQLLKANGIDEGVTQFIQSIMWFVGSLFLLVLSSQQLIWVVGCLFAIASFVLSLLENVDQPSLEQQGKIDQVVKGWKTLWNAPLLRQIVWIDILETIAGTVWIAAIILVFVHDALHVDKRWWGFINGTYFVGLIVGSIYCVKYSASIEKNIAQVMVIGSLFTCCATILFSVNSMPNIALFLTFCVGLFGQIKSIPQHTVIQTSVSRKELSAVYTALSAILTGGFGIASLVMGIIADVFGIRIVFMISGLLLAIVSILIGKNRQLFVIKMNQ
>NZ_CP006837.1|WP_025219186.1|1780792_1782040_-|ferric-reductase-like-transmembrane-domain-containing-protein
MKSYKGMLFILITMCGSGLLWYFATPIETIHVLNKLSHIVGGLAITGFFLVFLLATRVKILEKWFHGLEYVYMYHKYLAILSLGLVILHSQLQDLVPHGDQAIETPLSEFAKELGELAQNGFIGLIVIALFAKFLKYEHWRYIHRLLLIPYALGLYHAYFSSRYDLFQPTPLGIFTAITAIVGTMSALYMLTMYQDMRFKHTGKVSGIRKLGDSAVELELTLDRKLSYQNGQYIFLKIFQTGLEKAPHPFSISCGDGQKIYVTIKALGDFTKKVNALIQLDSKVAVEGPYGHLDFDKGYQQQIWIAGGVGITPFLSYLQSNPTDRDIELFYTYRGHNDAIHKDLLQKYAENNKHFKVNFIDTTTMDRLTFDDVSVPAHTSIFMCGPEKMVKRFTKQFKQSSTNDIDVNFEAFKFK
>NZ_CP006837.1|WP_024363418.1|1782257_1782746_+|metal-dependent-hydrolase
MQGNTHIVGGITASLAFAQISNDNPFVLVGAGVLGALLPDICHGGSKIGRTFPLISKMVNKLFGHRSFTHSLLFVVLVALLLQTIIPYPSIVAGLLIGMSSHIILDMGTKQGVKLFFPFNMSVRFPLTTRTGGKVEKIVFTLLSVLSLYLSYELISRFISEI
>NZ_CP006837.1|WP_038510243.1|1782842_1783631_-|squalene/phytoene-synthase-family-protein
MHVLKETSRTFYIPITFLQNDLKISVAAAYLAMRAIDEIEDHEKLSNDVKFDLLSAISELLKNEFDAEAYQTLLAPYADQLPEVSLRLADWLTFCPDESRKIVQASTSEMAYGMGKWAKANWQVHTREDLDDYTYYVAGLVGTMLSELWAWGAGIQTDRDLAIGYGRGLQAVNILRNQHEDLDERGVSFVPDGWTREDLFAYAEENLAKADLYIEAINKRTILLFCRLPLALAHKTLKAMQEGREKMTRAEVEQTVEEVQGE
>NZ_CP006837.1|WP_024363420.1|1783930_1784665_+|SDR-family-oxidoreductase
MGRLDNKIAIITGGASGMGASMAELFTKEGAIVIAADINEENLAKISELENVEGMKLDVSSDENWAAFTKAVIEKYGRIDILINNAGISSQKSPQDITDQDWAIMHKINSFGPFLGIKHVSKYMKEAGKGSIVNTSSYTAIIGSGLNSYTASKGSLRAIARAAAAELGKSNIRVNTVFPGVIETPMTANIGQFKEAMDMLVRATPMGRLGQPEEVANAILFLASDEASYITGGELVIDGGYSAQ
>NZ_CP006837.1|WP_024363421.1|1785107_1785944_+|type-II-pantothenate-kinase
MPKAIGIDAGGTLTKVAYLDEHNELILTTFPSNDLQSVMEWIRNNPDIEDIGVTGGRTEQLLDVIKTMKSIHYIVEFEATLKGVRFLLNKEGYFFERSMITNIGTGTSIHYMEGNTHIRVGGTGVGGGTLIGLSALTTGITDYNEIREMATKGNREGVDLLVKDIYQGMDTPIDGHLTASNFGKVSITEELKQPAEDIIATVQGLVGEVITTLSIQYAEEKNAQHIVYIGSTLSYNEHLAQVIANYTRTKKHTPVFINDHGFSGAVGALLNITEYTIV
>NZ_CP006837.1|WP_025219188.1|1786005_1788486_-|hypothetical-protein
MSSSLSSAKLNVPYSTTETIERPRLHDFFRENDQKRITILRAPAGYGKTTLLSQWLIHSQQPIAWVAIDQADNDPIRYWTFVFQAVAQACETDVDKVLAPLLQGQDVSTFDFLMESFIHELNTAKKSFHLVMDDYHLIENETIHRTMIKLIEQLPSYVHIYLTTRTALPLPIAIWRVKQWVHECNTEHLRFTYQETKQFFSLKNSISLNEHQLQTIQNKTEGWIAGLLLTSLTNFNEVQPFISNFLWQGIIHKLPKTIQNFLLKTSFLHELEPAICDQLIEETNSAELLAYLEENGLFTVCLQSSKLVFRYHHLFAEALQEELMKQYTEQEIKSLVEKTVQLIYGKGDYTSAIELALKHHLYEQAQQWISHHLVQLFLSGQTATFMRWLQQLRDNQQTVRYEMLILGYERAISILEMTTATSIMEELEQRQLSEQWMEQKENIAIANIYERTKAYALVASGGKLQTVKEILERQLTTQQAPCRWDKVRIPYNNFEYKLSRTNLASKGKLPAMDEVPKITQLFRNTNFKTLYVTAYISGIAAEVYYERNLLEDAQKELDIAIQLTQQQPDPNLFVPMYLLKANIYMHQQQTNTARAMLTQLLEDVVEKHWRNTIQIMIAFCYIVEGDDERAESILQATKTKQPFWMLVYARLLLLKKQPNDALSIVVQVKTKAQQDEQVGTIIEATILEAVCQLRLDNHDIALDTLHEALQLAAKFYYVRTLLDEKEILPLLNQYFQLESLTSKWNPVPKSYFDYLQKNCTVKKEPTDLLTPREQELFDLLTKGLSNQEIAKQLHLSNGTVRVYLSTIYSKLGVNSRAKVIALKNQR
>NZ_CP006837.1|WP_024363423.1|1788694_1788919_+|hypothetical-protein
MGNRNNKNNNKTMNKRTHNPFGTYKSKDLDDSNSNNNNPNDNLNEEFSAEFDAKAKNKNNKTNHDKNQQSNKKN
>NZ_CP006837.1|WP_162832722.1|1788935_1789076_+|hypothetical-protein
MAKKSKTSFKKKKKEDTHKRNDREEYSAEFNQVIHNNPQQPSKKSR
>NZ_CP006837.1|WP_025219189.1|1789240_1789567_+|YqzG/YhdC-family-protein
MRKILAALGIMMTVLALPQQMPDANAEQQTPAYAKWGKLAIEKTQSSYPNSKIIDYLHEGSEIKEGATIEKFKLWLQEGDKEFGVYVTIKYTTKTQQVVDIELQETSK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

32543 : 43992

uncultured_virus(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025218317.1\|32543_36056_-	peptidase S8	A0A1B0T6A2	Bacillus_phage	1.0e-49	36.9
WP_024362940.1\|36251_36767_-	nucleoside deaminase	NA	NA	NA	NA
WP_025218318.1\|36905_37241_+	winged helix-turn-helix transcriptional regulator	A0A218MNF3	uncultured_virus	4.7e-05	39.7
WP_025218319.1\|37272_38223_+	cation transporter	NA	NA	NA	NA
WP_024362943.1\|38299_38632_+	metal-sensing transcriptional repressor	NA	NA	NA	NA
WP_024362944.1\|38689_38896_+	copper chaperone CopZ	NA	NA	NA	NA
WP_025218320.1\|38977_41386_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.3e-125	40.3
WP_024362946.1\|41755_42394_+	deoxynucleoside kinase	A0A1G5SAJ8	Enterococcus_phage	3.2e-10	22.9
WP_024362947.1\|42390_43059_+	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	1.1e-24	35.8
WP_038509323.1\|43461_43992_+	TIGR00730 family Rossman fold protein	A0A1G5S9X4	Enterococcus_phage	8.8e-22	38.0

DBSCAN-SWA_2

312241 : 348847

Bacillus_phage(33.33%)

plate,holin,integrase,head,tail,terminase,capsid,portal,protease

attL 312211:312232|attR 350791:350812

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
312211:312232	attL	NA	NA	NA	NA
WP_025218436.1\|312241_313429_-\|integrase	site-specific integrase	A0A2I7SC08	Paenibacillus_phage	1.7e-73	39.8
WP_024360913.1\|313637_313856_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_080653265.1\|313992_314394_-	helix-turn-helix transcriptional regulator	A0A2H4JDE4	uncultured_Caudovirales_phage	4.6e-15	58.0
WP_025218437.1\|314578_314794_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_025218438.1\|314809_314992_+	helix-turn-helix domain-containing protein	U5P0W4	Brevibacillus_phage	1.6e-07	51.0
WP_038509361.1\|314988_315168_+	hypothetical protein	A0A2H4J246	uncultured_Caudovirales_phage	4.2e-08	65.0
WP_025218439.1\|315221_315569_+	hypothetical protein	NA	NA	NA	NA
WP_025218440.1\|315568_315826_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	1.3e-15	82.0
WP_025218441.1\|316048_317272_+	DEAD/DEAH box helicase	A0A1B1P7L4	Bacillus_phage	2.2e-201	82.3
WP_025218442.1\|317272_317599_+	hypothetical protein	NA	NA	NA	NA
WP_025218443.1\|317567_318164_-	hypothetical protein	NA	NA	NA	NA
WP_025218444.1\|318274_318559_+	nuclease	A0A1B1P7M6	Bacillus_phage	1.4e-45	91.4
WP_025218445.1\|318555_320412_+	AAA family ATPase	A0A1B1P7N0	Bacillus_phage	1.3e-221	73.8
WP_025218446.1\|320442_320754_+	hypothetical protein	A0A1B1P7N6	Bacillus_phage	9.8e-21	61.7
WP_025218447.1\|320753_321242_+	DUF669 domain-containing protein	A0A1B1P7N3	Bacillus_phage	2.4e-66	74.8
WP_025218448.1\|321290_321746_-	hypothetical protein	NA	NA	NA	NA
WP_025218449.1\|321841_323524_+	DNA polymerase	A0A1B1P7M5	Bacillus_phage	4.9e-276	80.5
WP_025218450.1\|323566_323833_-	hypothetical protein	A0A2H4JB42	uncultured_Caudovirales_phage	1.4e-15	42.9
WP_025218451.1\|323926_325795_+	DNA primase	A0A1B1P7L5	Bacillus_phage	5.1e-298	79.6
WP_025218452.1\|326280_326691_+	hypothetical protein	A0A1C8E9D1	Bacillus_phage	1.5e-37	59.8
WP_025218453.1\|326856_327162_+	hypothetical protein	A0A2H4J758	uncultured_Caudovirales_phage	9.9e-18	46.4
WP_025218454.1\|327158_327506_+	HNH endonuclease	A0A2H4JA38	uncultured_Caudovirales_phage	5.2e-39	60.7
WP_025218455.1\|327627_328161_+	hypothetical protein	A0A2H4J216	uncultured_Caudovirales_phage	3.4e-37	55.2
WP_025218456.1\|328157_329876_+\|terminase	terminase large subunit	A0A1B2AQ28	Phage_Wrath	1.4e-289	83.1
WP_025218457.1\|329890_331105_+\|portal	phage portal protein	A0A2H4J9C7	uncultured_Caudovirales_phage	2.2e-148	66.7
WP_025218458.1\|331070_331658_+\|head,protease	HK97 family phage prohead protease	A0A1B2APW1	Phage_Wrath	5.7e-70	70.0
WP_025218459.1\|331650_332988_+\|capsid	phage major capsid protein	A0A1B2APY9	Phage_Wrath	4.2e-137	65.1
WP_025218460.1\|332992_333250_+\|head,tail	phage head-tail connector protein	A0A1B1P7M9	Bacillus_phage	2.3e-20	56.6
WP_025218461.1\|333230_333569_+\|head	phage head closure protein	NA	NA	NA	NA
WP_025218462.1\|333565_333994_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_025218463.1\|333990_334488_+	hypothetical protein	NA	NA	NA	NA
WP_025218464.1\|334491_335550_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0A7S0D2	Clostridium_phage	7.1e-71	44.2
WP_025218465.1\|335564_335999_+\|tail	phage tail tube protein	A0A0A7RVT1	Clostridium_phage	2.8e-26	41.1
WP_025218466.1\|336020_336413_+	hypothetical protein	A0A0A8WIB2	Clostridium_phage	9.5e-13	34.5
WP_025218467.1\|336622_338749_+\|tail	phage tail tape measure protein	A0A2H5BLS1	Streptomyces_phage	4.8e-42	32.0
WP_025218468.1\|338762_339185_+	hypothetical protein	A0A0N7ACL7	Bacillus_phage	1.6e-05	29.2
WP_025218469.1\|339184_340162_+	hypothetical protein	NA	NA	NA	NA
WP_025218470.1\|340163_340523_+	DUF2577 domain-containing protein	NA	NA	NA	NA
WP_025218471.1\|340522_340969_+	DUF2634 domain-containing protein	NA	NA	NA	NA
WP_025218472.1\|340969_342010_+\|plate	baseplate J/gp47 family protein	A0A0A7RUN3	Clostridium_phage	4.0e-50	34.6
WP_025218473.1\|342006_342354_+	hypothetical protein	A0A1B1INQ1	uncultured_Mediterranean_phage	6.9e-07	35.1
WP_158497860.1\|342457_343183_+	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_025218475.1\|343182_343524_+	hypothetical protein	NA	NA	NA	NA
WP_025218476.1\|343524_344274_+	hypothetical protein	NA	NA	NA	NA
WP_025218477.1\|344278_344545_+	hypothetical protein	NA	NA	NA	NA
WP_158497861.1\|344547_344721_+	hypothetical protein	NA	NA	NA	NA
WP_025218478.1\|344795_345572_+	hypothetical protein	A0A0S2SXZ1	Bacillus_phage	7.7e-83	62.3
WP_025218479.1\|345711_345963_+	hypothetical protein	NA	NA	NA	NA
WP_025218480.1\|346155_346614_+\|holin	phage holin family protein	D7RWK5	Brochothrix_phage	3.3e-33	57.0
WP_025218481.1\|346613_347282_+	M15 family metallopeptidase	A0A2D1GQ84	Lysinibacillus_phage	1.1e-58	53.1
WP_025218482.1\|347404_348307_-	hypothetical protein	NA	NA	NA	NA
WP_025218483.1\|348325_348847_-	SHOCT domain-containing protein	Q4ZA70	Staphylococcus_virus	7.9e-07	27.6
350791:350812	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1509476 : 1534245

Brevibacillus_phage(50.0%)

holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025219028.1\|1509476_1509767_-\|holin	phage holin family protein	A0A142F1N6	Bacillus_phage	3.0e-24	59.8
WP_144340672.1\|1509784_1510171_-	hypothetical protein	NA	NA	NA	NA
WP_025219030.1\|1510273_1510723_-	hypothetical protein	A0A0K2FLF1	Brevibacillus_phage	8.9e-15	36.1
WP_025219031.1\|1510745_1512662_-	DNRLRE domain-containing protein	NA	NA	NA	NA
WP_158497872.1\|1512693_1514775_-	discoidin domain-containing protein	G3MAA7	Bacillus_virus	2.1e-114	46.5
WP_025219033.1\|1514841_1515606_-	hypothetical protein	G3MAA6	Bacillus_virus	6.1e-08	55.2
WP_025219034.1\|1515647_1516757_-	discoidin domain-containing protein	NA	NA	NA	NA
WP_025219035.1\|1516757_1517603_-	hypothetical protein	G3MAA5	Bacillus_virus	8.8e-56	55.8
WP_025219036.1\|1517599_1518673_-	hypothetical protein	G3MAA4	Bacillus_virus	9.7e-52	35.5
WP_025219037.1\|1518690_1519020_-	hypothetical protein	NA	NA	NA	NA
WP_025219038.1\|1519045_1519642_-	hypothetical protein	NA	NA	NA	NA
WP_025219039.1\|1519746_1520493_-	hypothetical protein	A0A0K2FLS8	Brevibacillus_phage	4.1e-25	35.2
WP_025219040.1\|1520555_1521719_-	hypothetical protein	A0A0K2FMC4	Brevibacillus_phage	6.6e-70	36.0
WP_137036903.1\|1521742_1522114_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_025219042.1\|1522168_1525933_-\|tail	phage tail protein	A0A0K2FLF6	Brevibacillus_phage	1.1e-238	32.4
WP_025219043.1\|1525956_1526598_-	hypothetical protein	A0A0K2FM10	Brevibacillus_phage	1.1e-31	35.8
WP_025219044.1\|1526609_1527266_-	hypothetical protein	NA	NA	NA	NA
WP_025219045.1\|1527265_1527862_-\|tail	phage tail family protein	A0A0K2FMB9	Brevibacillus_phage	9.9e-38	39.4
WP_025219046.1\|1527861_1534245_-	peptidoglycan DD-metalloendopeptidase family protein	A0A0H3V0Q1	Geobacillus_virus	1.3e-18	22.7

DBSCAN-SWA_4

2488112 : 2558194

Bacillus_phage(14.0%)

holin,plate,integrase,head,tail,terminase,capsid,portal,protease

attL 2491075:2491090|attR 2559271:2559286

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025219658.1\|2488112_2488529_-\|holin	phage holin family protein	S6AVT9	Thermus_phage	1.8e-33	57.7
WP_158497884.1\|2488727_2488889_-	hypothetical protein	NA	NA	NA	NA
WP_025219659.1\|2488890_2489202_-	hypothetical protein	NA	NA	NA	NA
WP_025219660.1\|2489198_2490506_-	hypothetical protein	NA	NA	NA	NA
WP_025219661.1\|2490505_2491402_-	hypothetical protein	E2ELJ8	Clostridium_phage	2.1e-52	40.8
2491075:2491090	attL	NA	NA	NA	NA
WP_025219662.1\|2491404_2492502_-	siphovirus ReqiPepy6 Gp37-like family protein	D2J072	Enterococcus_phage	1.5e-31	29.3
WP_025219663.1\|2492504_2493380_-\|tail	phage tail family protein	NA	NA	NA	NA
WP_025219664.1\|2493394_2498230_-	hypothetical protein	A6XMK6	Bacillus_virus	2.5e-131	51.9
WP_025219665.1\|2498495_2498852_-	hypothetical protein	A6XMK4	Bacillus_virus	7.2e-28	51.7
WP_038510365.1\|2498873_2499452_-\|tail	phage tail protein	A0A0U4JWV5	Exiguobacterium_phage	9.6e-54	59.6
WP_025219667.1\|2499514_2499832_-	hypothetical protein	A0A0U4JNN6	Exiguobacterium_phage	7.9e-18	48.1
WP_025219668.1\|2499828_2500188_-	hypothetical protein	D2XR21	Bacillus_phage	6.0e-22	50.0
WP_025219669.1\|2500168_2500555_-\|head	phage head closure protein	A0A0U4JE41	Bacillus_phage	3.9e-11	32.5
WP_052599582.1\|2500541_2500790_-	hypothetical protein	A0A2H4JG04	uncultured_Caudovirales_phage	4.0e-25	72.2
WP_025219671.1\|2500840_2501032_-	hypothetical protein	NA	NA	NA	NA
WP_025219672.1\|2501065_2502226_-\|capsid	phage major capsid protein	A0A2H4JH29	uncultured_Caudovirales_phage	8.4e-142	68.5
WP_025219673.1\|2502245_2502950_-\|protease	ATP-dependent Clp protease proteolytic subunit	F8J1B3	Lactobacillus_phage	7.6e-29	42.1
WP_025219674.1\|2502939_2504091_-\|portal	phage portal protein	A8AT96	Listeria_phage	7.4e-106	52.1
WP_025219675.1\|2504106_2505792_-\|terminase	terminase large subunit	D2XR15	Bacillus_phage	2.4e-246	75.9
WP_025219676.1\|2505788_2506121_-	hypothetical protein	D2XR14	Bacillus_phage	1.5e-14	41.8
WP_025219677.1\|2506239_2506575_-	HNH endonuclease	D2XR61	Bacillus_phage	1.1e-38	67.9
WP_025219678.1\|2506580_2506898_-	hypothetical protein	NA	NA	NA	NA
WP_025219679.1\|2507146_2507380_-	hypothetical protein	NA	NA	NA	NA
WP_025219680.1\|2507688_2508132_-	hypothetical protein	NA	NA	NA	NA
WP_025219681.1\|2508547_2508949_-	hypothetical protein	A0A2H4JFW6	uncultured_Caudovirales_phage	1.9e-37	59.2
WP_025219682.1\|2509015_2509360_-	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	3.0e-23	44.2
WP_025219683.1\|2509413_2509629_-	hypothetical protein	NA	NA	NA	NA
WP_158497885.1\|2509925_2512820_-	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_025219685.1\|2512996_2513266_-	hypothetical protein	NA	NA	NA	NA
WP_025219686.1\|2513298_2513499_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_081769955.1\|2513712_2514234_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_038509697.1\|2514261_2515479_+\|integrase	site-specific integrase	A0A1Q1PVS7	Staphylococcus_phage	5.9e-53	35.5
WP_025219689.1\|2515504_2516113_-	YpjP family protein	NA	NA	NA	NA
WP_025219690.1\|2516698_2517136_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_025219691.1\|2517665_2518517_-	AraC family transcriptional regulator	A0A1B0RXG1	Streptococcus_phage	1.7e-19	40.3
WP_025219692.1\|2518659_2519544_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_158497886.1\|2520179_2520356_-	hypothetical protein	NA	NA	NA	NA
WP_025219694.1\|2521131_2521923_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_024364685.1\|2521910_2522342_-	BrxA/BrxB family bacilliredoxin	NA	NA	NA	NA
WP_025219695.1\|2522667_2523966_+	Ig domain-containing protein	A0A1P8BL30	Lactococcus_phage	1.0e-07	39.6
WP_025219696.1\|2524016_2524682_-	M15 family metallopeptidase	A0A2D1GQ84	Lysinibacillus_phage	1.7e-54	52.3
WP_025219697.1\|2524678_2525095_-\|holin	phage holin family protein	S6AVT9	Thermus_phage	3.7e-31	55.9
WP_081769896.1\|2525171_2525447_-	hypothetical protein	NA	NA	NA	NA
WP_158497887.1\|2525527_2525695_-	hypothetical protein	NA	NA	NA	NA
WP_025219698.1\|2525696_2525972_-	hypothetical protein	NA	NA	NA	NA
WP_025219699.1\|2525989_2526886_-	hypothetical protein	NA	NA	NA	NA
WP_052599485.1\|2526882_2527587_-\|tail	phage tail protein	A0A0A7RTP0	Clostridium_phage	8.1e-47	61.3
WP_025219700.1\|2527587_2528235_-\|tail	phage tail protein I	A0A2K9V471	Faecalibacterium_phage	4.4e-23	31.4
WP_025219701.1\|2528227_2529343_-\|plate	baseplate J/gp47 family protein	A0A0C5AEG2	Bacteriophage	1.7e-78	42.0
WP_025219702.1\|2529329_2529647_-	hypothetical protein	A0A067ZJ13	Vibrio_phage	5.5e-11	39.2
WP_052599488.1\|2529651_2530308_-\|tail	phage tail protein	A0A067ZI88	Vibrio_phage	2.7e-12	35.2
WP_052599491.1\|2530322_2530730_-\|plate	phage baseplate assembly protein V	NA	NA	NA	NA
WP_025219703.1\|2530729_2531749_-	hypothetical protein	A0A067ZG47	Vibrio_phage	7.4e-41	32.8
WP_025219704.1\|2531745_2531961_-\|tail	tail protein X	A0A0C5AEF4	Bacteriophage	1.1e-07	42.2
WP_025219705.1\|2531953_2534737_-\|tail	phage tail tape measure protein	A0A0C5AJ16	Paenibacillus_phage	8.9e-97	52.2
WP_025219706.1\|2534893_2535226_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_025219707.1\|2535247_2535763_-\|tail	phage major tail tube protein	A0A0E3Y6F4	Fusobacterium_phage	1.1e-21	28.6
WP_025219708.1\|2535774_2537217_-	hypothetical protein	A0A059WKP9	Vibrio_phage	8.9e-117	46.0
WP_025219709.1\|2537213_2537513_-	hypothetical protein	NA	NA	NA	NA
WP_025219710.1\|2537505_2538000_-	hypothetical protein	NA	NA	NA	NA
WP_025219711.1\|2538004_2538553_-\|tail	phage tail protein	A0A067ZG41	Vibrio_phage	1.5e-19	35.0
WP_025219712.1\|2538561_2538891_-	hypothetical protein	NA	NA	NA	NA
WP_025219713.1\|2538883_2539249_-	hypothetical protein	NA	NA	NA	NA
WP_025219714.1\|2539261_2540287_-\|capsid	major capsid protein	A0A059WRQ2	Vibrio_phage	7.1e-52	36.4
WP_025219715.1\|2540291_2540657_-	hypothetical protein	NA	NA	NA	NA
WP_025219716.1\|2540658_2541723_-\|protease	Clp protease ClpP	A0A0A7RWX3	Clostridium_phage	1.4e-45	45.1
WP_025219717.1\|2541712_2543284_-\|portal	phage portal protein	A0A067ZJA4	Vibrio_phage	3.0e-158	56.0
WP_081769956.1\|2543296_2543491_-	hypothetical protein	NA	NA	NA	NA
WP_025219719.1\|2543533_2545345_-\|terminase	phage terminase large subunit family protein	A0A2K9V3X4	Faecalibacterium_phage	2.8e-176	52.0
WP_025219720.1\|2545307_2545877_-	hypothetical protein	A0A0C5AN04	Bacteriophage	1.1e-09	31.0
WP_025219721.1\|2546416_2546986_-\|integrase	tyrosine-type recombinase/integrase	A0A0S2GLG4	Bacillus_phage	8.5e-47	55.6
WP_025219722.1\|2546982_2547426_-	hypothetical protein	Q0H270	Geobacillus_phage	1.8e-23	39.6
WP_025219723.1\|2547606_2548485_-	hypothetical protein	NA	NA	NA	NA
WP_025219724.1\|2548710_2549283_-	hypothetical protein	NA	NA	NA	NA
WP_025219725.1\|2549385_2549583_-	hypothetical protein	A0A1L2JY31	Aeribacillus_phage	2.9e-10	54.5
WP_025219726.1\|2549674_2549893_-	hypothetical protein	NA	NA	NA	NA
WP_137036959.1\|2549929_2550049_-	BH0509 family protein	NA	NA	NA	NA
WP_025219727.1\|2550041_2550536_-	hypothetical protein	NA	NA	NA	NA
WP_052599493.1\|2550532_2551810_-	replicative DNA helicase	A0A0U4B0A1	Bacillus_phage	1.3e-71	37.9
WP_025219729.1\|2551809_2552616_-	conserved phage C-terminal domain-containing protein	A0A2H4JEZ8	uncultured_Caudovirales_phage	3.9e-45	49.4
WP_025219730.1\|2552612_2553263_-	ORF6N domain-containing protein	A0A0K2CNP0	Brevibacillus_phage	9.2e-29	34.9
WP_025219731.1\|2553366_2553576_-	hypothetical protein	NA	NA	NA	NA
WP_025219732.1\|2553693_2554059_-	hypothetical protein	NA	NA	NA	NA
WP_025219733.1\|2554078_2554348_-	helix-turn-helix transcriptional regulator	S5MNZ7	Brevibacillus_phage	1.3e-16	57.0
WP_025219734.1\|2554423_2554732_-	hypothetical protein	NA	NA	NA	NA
WP_137036958.1\|2554753_2555032_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_052599496.1\|2555000_2555225_-	helix-turn-helix transcriptional regulator	S4SUN2	Staphylococcus_phage	3.7e-06	48.3
WP_025219737.1\|2555430_2555670_-	hypothetical protein	NA	NA	NA	NA
WP_025219738.1\|2555982_2556174_-	helix-turn-helix transcriptional regulator	Q0H243	Geobacillus_phage	1.6e-13	61.0
WP_167331271.1\|2556324_2556705_+	helix-turn-helix domain-containing protein	Q0H244	Geobacillus_phage	4.7e-17	62.2
WP_025219740.1\|2556851_2557574_+	SWIM zinc finger family protein	NA	NA	NA	NA
WP_025219741.1\|2557834_2558194_+	helix-turn-helix transcriptional regulator	A0A290GJU0	Caldibacillus_phage	8.1e-11	37.5
2559271:2559286	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3183224 : 3244682

Bacillus_phage(23.26%)

holin,tRNA,head,tail,terminase,capsid,portal,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024363169.1\|3183224_3184370_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.0e-86	44.8
WP_025220112.1\|3184488_3185532_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_024363171.1\|3185550_3186555_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	2.0e-06	23.9
WP_025220113.1\|3186573_3187194_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_052599508.1\|3187307_3188141_-	phosphotransferase	NA	NA	NA	NA
WP_174412977.1\|3188175_3189219_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_024363175.1\|3189332_3189866_+	transcription repressor NadR	NA	NA	NA	NA
WP_024363176.1\|3190014_3190413_-	thiol-disulfide oxidoreductase DCC family protein	NA	NA	NA	NA
WP_025220115.1\|3190435_3191317_-	prephenate dehydratase	NA	NA	NA	NA
WP_024363178.1\|3191658_3192114_-	ACT domain-containing protein	NA	NA	NA	NA
WP_025220116.1\|3192138_3193428_-	GTPase ObgE	NA	NA	NA	NA
WP_025220117.1\|3193433_3193961_-	Spo0B domain-containing protein	NA	NA	NA	NA
WP_024363181.1\|3194098_3194398_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_024363182.1\|3194394_3194751_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_010860053.1\|3194765_3195074_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_025220118.1\|3195209_3195821_-	stage IV sporulation protein FB	NA	NA	NA	NA
WP_025220119.1\|3195810_3196365_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_024363185.1\|3196492_3197290_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_025220120.1\|3197291_3197960_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_024363187.1\|3197989_3198514_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_024363188.1\|3198513_3199425_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_024363189.1\|3199438_3200458_-	rod shape-determining protein	NA	NA	NA	NA
WP_158497892.1\|3201503_3201671_-	hypothetical protein	NA	NA	NA	NA
WP_025220121.1\|3201836_3202733_-	helix-turn-helix domain-containing protein	A0A288WFX2	Bacillus_phage	1.8e-11	26.8
WP_158497893.1\|3202755_3202932_-	hypothetical protein	NA	NA	NA	NA
WP_025220122.1\|3203123_3203345_+	helix-turn-helix transcriptional regulator	L0L8F4	Bacillus_phage	2.2e-06	47.7
WP_025220123.1\|3203421_3204294_+	hypothetical protein	NA	NA	NA	NA
WP_174412978.1\|3204407_3204599_+	type II toxin-antitoxin system HicA family toxin	A0A1L2JY37	Aeribacillus_phage	2.1e-18	67.7
WP_025220125.1\|3204625_3205039_+	type II toxin-antitoxin system HicB family antitoxin	A0A0K2CYJ8	Paenibacillus_phage	7.1e-43	61.8
WP_025220126.1\|3205060_3205420_-	hypothetical protein	NA	NA	NA	NA
WP_052599509.1\|3205412_3205637_-	transcriptional regulator	NA	NA	NA	NA
WP_158497894.1\|3205804_3205954_+	hypothetical protein	NA	NA	NA	NA
WP_024364127.1\|3206210_3206450_+	hypothetical protein	NA	NA	NA	NA
WP_025220127.1\|3206577_3207246_-	M15 family metallopeptidase	A0A2D1GQ84	Lysinibacillus_phage	2.5e-58	53.1
WP_025220128.1\|3207242_3207659_-\|holin	phage holin family protein	S6AVT9	Thermus_phage	2.3e-33	56.9
WP_158497895.1\|3207857_3208025_-	hypothetical protein	NA	NA	NA	NA
WP_025220129.1\|3208074_3208446_-	hypothetical protein	NA	NA	NA	NA
WP_025220130.1\|3208451_3209441_-	hypothetical protein	NA	NA	NA	NA
WP_025220131.1\|3209440_3210340_-	hypothetical protein	E2ELJ8	Clostridium_phage	4.2e-48	50.8
WP_025220132.1\|3210342_3211440_-	siphovirus ReqiPepy6 Gp37-like family protein	D2J072	Enterococcus_phage	2.6e-31	29.3
WP_025220133.1\|3211442_3212321_-\|tail	phage tail family protein	NA	NA	NA	NA
WP_025220134.1\|3212336_3217334_-\|tail	phage tail tape measure protein	A0A1Q1PW35	Staphylococcus_phage	2.4e-76	45.6
WP_025220135.1\|3217529_3217841_-	hypothetical protein	A0A288WGA9	Bacillus_phage	5.0e-09	40.4
WP_025220136.1\|3217913_3218498_-	hypothetical protein	NA	NA	NA	NA
WP_052599513.1\|3218518_3218863_-	hypothetical protein	NA	NA	NA	NA
WP_025220138.1\|3218859_3219264_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_025220139.1\|3219264_3219597_-\|head	phage head closure protein	A0A088F713	Idiomarinaceae_phage	3.3e-06	31.1
WP_025220140.1\|3219574_3219907_-\|head,tail	phage gp6-like head-tail connector protein	A0A0K2CZI4	Paenibacillus_phage	5.0e-07	38.8
WP_025220141.1\|3219906_3220143_-	hypothetical protein	NA	NA	NA	NA
WP_025220142.1\|3220188_3221331_-\|capsid	phage major capsid protein	A0A0K2CZ99	Paenibacillus_phage	8.6e-131	63.3
WP_025220143.1\|3221345_3222083_-\|protease	Clp protease ClpP	A0A0U3U021	Bacillus_phage	5.1e-60	47.2
WP_052599607.1\|3222069_3223275_-\|portal	phage portal protein	A0A0U3SQF0	Bacillus_phage	9.6e-149	63.6
WP_025220145.1\|3223327_3225031_-\|terminase	terminase large subunit	Q2LII3	Bacillus_virus	1.8e-209	64.2
WP_025220146.1\|3225027_3225546_-\|terminase	phage terminase small subunit P27 family	Q2I8G1	Bacillus_phage	9.2e-48	60.1
WP_025220147.1\|3225671_3226043_-	HNH endonuclease	A0A1U7Q1S7	Geobacillus_virus	1.5e-31	51.2
WP_025220148.1\|3226032_3226350_-	hypothetical protein	A0A0K2CZP5	Paenibacillus_phage	1.4e-11	41.1
WP_025220149.1\|3226353_3226803_-	hypothetical protein	NA	NA	NA	NA
WP_025220150.1\|3226807_3227107_-	hypothetical protein	NA	NA	NA	NA
WP_025220151.1\|3227218_3227857_-	hypothetical protein	NA	NA	NA	NA
WP_025220152.1\|3228180_3228567_-	hypothetical protein	D2XR52	Bacillus_phage	5.3e-08	35.0
WP_038509846.1\|3228603_3229005_-	hypothetical protein	A0A2H4JFW6	uncultured_Caudovirales_phage	1.3e-33	56.1
WP_167331269.1\|3229035_3229209_-	hypothetical protein	A0A2I6QR06	Streptococcus_phage	7.3e-10	54.7
WP_025220154.1\|3229234_3229690_-	methyltransferase domain-containing protein	A0A059T693	Listeria_phage	1.4e-63	69.1
WP_025220155.1\|3229704_3230232_-	hypothetical protein	A0A1Q1PVZ6	Staphylococcus_phage	1.9e-08	35.0
WP_025220156.1\|3230228_3230585_-	hypothetical protein	A0A2P1CA53	Pseudomonas_phage	7.0e-07	42.9
WP_025220157.1\|3230585_3230981_-	hypothetical protein	NA	NA	NA	NA
WP_025220158.1\|3231062_3231272_-	hypothetical protein	A0A2D1GQB9	Lysinibacillus_phage	3.8e-13	54.7
WP_025220159.1\|3231344_3231752_-	hypothetical protein	A0A2H4JBP0	uncultured_Caudovirales_phage	9.1e-27	57.8
WP_025220160.1\|3231768_3232194_-	DUF1064 domain-containing protein	A0A2P1JTY5	Anoxybacillus_phage	8.9e-33	54.5
WP_025220161.1\|3232206_3232740_-	HNH endonuclease	A0A218KBW3	Bacillus_phage	3.5e-50	54.7
WP_025220162.1\|3232765_3233275_-	single-stranded DNA-binding protein	A0A290GHL8	Caldibacillus_phage	8.4e-38	51.2
WP_025220163.1\|3233281_3233716_-	hypothetical protein	NA	NA	NA	NA
WP_025220164.1\|3233702_3234938_-	DNA helicase	A0A0U4B0A1	Bacillus_phage	5.4e-70	39.0
WP_025220165.1\|3234937_3235783_-	phage replisome organizer N-terminal domain-containing protein	V9QKF6	Oenococcus_phage	2.4e-37	37.0
WP_025220166.1\|3235794_3236424_-	ERF family protein	A0A2D1GQF7	Lysinibacillus_phage	6.5e-48	51.9
WP_025220167.1\|3236438_3236939_-	siphovirus Gp157 family protein	B6CXH7	Clostridium_phage	3.2e-13	34.9
WP_025220168.1\|3236935_3237652_-	hypothetical protein	A0A2H4J2J8	uncultured_Caudovirales_phage	1.9e-11	45.2
WP_025220169.1\|3237648_3237840_-	hypothetical protein	NA	NA	NA	NA
WP_025220170.1\|3237848_3238121_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	2.1e-11	55.7
WP_025220171.1\|3238117_3238477_-	hypothetical protein	NA	NA	NA	NA
WP_158497896.1\|3238460_3238613_-	hypothetical protein	NA	NA	NA	NA
WP_025220172.1\|3238596_3239016_-	hypothetical protein	NA	NA	NA	NA
WP_025220173.1\|3239044_3239875_-	hypothetical protein	A0A2H4J989	uncultured_Caudovirales_phage	8.4e-35	40.9
WP_158497897.1\|3239921_3240083_-	hypothetical protein	NA	NA	NA	NA
WP_025220174.1\|3240079_3240802_-	ORF6C domain-containing protein	S5MP04	Brevibacillus_phage	3.1e-41	40.9
WP_025220175.1\|3240862_3241372_+	hypothetical protein	NA	NA	NA	NA
WP_158497898.1\|3241364_3241538_-	hypothetical protein	NA	NA	NA	NA
WP_025220176.1\|3241664_3241883_-	helix-turn-helix transcriptional regulator	A6M975	Geobacillus_virus	3.0e-08	54.4
WP_025220177.1\|3242103_3242742_+	XRE family transcriptional regulator	A0A2I7SCV6	Paenibacillus_phage	3.6e-38	41.7
WP_025220178.1\|3242821_3243154_+	hypothetical protein	NA	NA	NA	NA
WP_025220179.1\|3243251_3244682_+	recombinase family protein	A0A2H4JFH9	uncultured_Caudovirales_phage	8.8e-133	53.6

DBSCAN-SWA_6

3326101 : 3336450

Bacillus_phage(42.86%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025220225.1\|3326101_3327064_+	S8 family peptidase	A0A127AWU5	Bacillus_phage	4.6e-77	50.3
WP_025220226.1\|3327063_3327873_+	endonuclease	A0A2P0VMP9	Tetraselmis_virus	5.7e-12	32.1
WP_025220227.1\|3328305_3328803_-	ATP-binding protein	A0A1Q1PVZ2	Staphylococcus_phage	9.4e-58	63.6
WP_025220228.1\|3329202_3329532_-	four-helix bundle copper-binding protein	NA	NA	NA	NA
WP_025220229.1\|3329854_3330433_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_025220230.1\|3330722_3331283_+	helix-turn-helix domain-containing protein	A0A1B1P776	Bacillus_phage	2.3e-12	36.2
WP_038509858.1\|3331300_3331699_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.1e-29	56.6
WP_158497902.1\|3331685_3332111_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.0e-08	29.8
WP_025220231.1\|3332352_3332679_-	hypothetical protein	NA	NA	NA	NA
WP_025220232.1\|3333123_3336450_-	AAA family ATPase	A0A076FFX0	Aureococcus_anophage	1.2e-10	22.7

DBSCAN-SWA_7

3915687 : 3964442

Bacillus_phage(35.29%)

holin,tRNA,integrase,head,tail,terminase,capsid,portal,protease

attL 3929368:3929386|attR 3964589:3964607

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025220535.1\|3915687_3916161_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_025220536.1\|3916175_3917306_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_025220537.1\|3917365_3918055_+\|tRNA	tRNA synthetase subunit beta	NA	NA	NA	NA
WP_024362339.1\|3918069_3918579_+	hypothetical protein	L0L915	Bacillus_phage	1.8e-16	34.3
WP_025220538.1\|3918859_3920434_+	catalase	A0A2K9L572	Tupanvirus	1.5e-101	43.0
WP_024362341.1\|3920569_3921472_-	LD-carboxypeptidase	NA	NA	NA	NA
WP_024362342.1\|3921591_3922470_+	DMT family transporter	NA	NA	NA	NA
WP_024362343.1\|3922511_3923225_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_025220539.1\|3923421_3924165_+	arylamine N-acetyltransferase	NA	NA	NA	NA
WP_025220540.1\|3924201_3925293_-	S-layer homology domain-containing protein	G9J240	Bacillus_phage	6.3e-14	28.3
WP_024362347.1\|3927574_3928870_+	S8 family peptidase	A0A1B0T6A2	Bacillus_phage	1.0e-34	37.2
3929368:3929386	attL	NA	NA	NA	NA
WP_158497906.1\|3929620_3929788_+	hypothetical protein	NA	NA	NA	NA
WP_025220541.1\|3929867_3930431_+	DUF5067 domain-containing protein	NA	NA	NA	NA
WP_025220542.1\|3930484_3931225_-	N-acetylmuramoyl-L-alanine amidase	D6QWL8	uncultured_phage	3.2e-30	37.2
WP_025220543.1\|3931224_3931485_-\|holin	phage holin	A0A1Q1PW49	Staphylococcus_phage	1.2e-19	54.9
WP_025220544.1\|3931474_3931744_-	hypothetical protein	NA	NA	NA	NA
WP_025220545.1\|3931801_3931999_-	hypothetical protein	NA	NA	NA	NA
WP_158497907.1\|3932037_3932199_-	hypothetical protein	NA	NA	NA	NA
WP_025220546.1\|3932200_3932545_-	hypothetical protein	NA	NA	NA	NA
WP_025220547.1\|3932547_3933882_-	hypothetical protein	NA	NA	NA	NA
WP_025220548.1\|3933881_3934778_-	hypothetical protein	E2ELJ8	Clostridium_phage	2.2e-49	51.9
WP_025220549.1\|3934780_3935878_-	siphovirus ReqiPepy6 Gp37-like family protein	D2J072	Enterococcus_phage	3.1e-29	27.3
WP_025220550.1\|3935880_3936756_-\|tail	phage tail family protein	NA	NA	NA	NA
WP_025220551.1\|3936770_3941270_-	hypothetical protein	A6XMK6	Bacillus_virus	6.6e-150	53.4
WP_025220552.1\|3941539_3941893_-	hypothetical protein	A0A2H4J224	uncultured_Caudovirales_phage	2.6e-22	46.2
WP_038510611.1\|3941907_3942516_-\|tail	phage tail protein	D2XR23	Bacillus_phage	1.0e-58	59.2
WP_025220554.1\|3942617_3942932_-	hypothetical protein	A0A2H4J234	uncultured_Caudovirales_phage	2.1e-18	50.5
WP_052599535.1\|3942928_3943333_-	hypothetical protein	D2XR21	Bacillus_phage	4.1e-19	48.3
WP_025220556.1\|3943283_3943628_-	hypothetical protein	NA	NA	NA	NA
WP_025220557.1\|3943614_3943911_-	hypothetical protein	A0A0S2SXS0	Bacillus_phage	1.9e-18	49.5
WP_025220558.1\|3943910_3944096_-	hypothetical protein	A0A0S2SXV2	Bacillus_phage	7.6e-13	61.4
WP_025220559.1\|3944115_3945402_-\|capsid	phage major capsid protein	Q0H261	Geobacillus_phage	3.9e-140	80.4
WP_025220560.1\|3945398_3945980_-\|head,protease	HK97 family phage prohead protease	Q0H262	Geobacillus_phage	2.6e-67	69.4
WP_025220561.1\|3945972_3947169_-\|portal	phage portal protein	Q0H263	Geobacillus_phage	2.7e-151	65.1
WP_158497908.1\|3947169_3947340_-	hypothetical protein	NA	NA	NA	NA
WP_025220562.1\|3947347_3949102_-\|terminase	terminase large subunit	C5J959	Streptococcus_phage	1.2e-200	59.5
WP_052599622.1\|3949107_3949437_-\|terminase	P27 family phage terminase small subunit	Q0H265	Geobacillus_phage	2.3e-28	71.4
WP_025220564.1\|3949586_3949880_-	HNH endonuclease	A0A0S2SXR6	Bacillus_phage	3.4e-31	65.9
WP_025220565.1\|3949879_3950536_-	hypothetical protein	NA	NA	NA	NA
WP_025220566.1\|3950553_3950778_-	hypothetical protein	NA	NA	NA	NA
WP_144340676.1\|3950794_3951004_-	hypothetical protein	NA	NA	NA	NA
WP_025220568.1\|3951018_3951375_-	hypothetical protein	NA	NA	NA	NA
WP_025220569.1\|3951455_3951674_-	hypothetical protein	NA	NA	NA	NA
WP_025220570.1\|3951942_3952512_-	hypothetical protein	A0A1S7FZ07	Listeria_phage	8.9e-12	30.7
WP_025220571.1\|3952548_3952737_-	hypothetical protein	A0A218KC21	Bacillus_phage	1.4e-17	69.0
WP_137036947.1\|3953049_3953634_-	hypothetical protein	A0A0K2CNV8	Brevibacillus_phage	1.7e-18	53.3
WP_025220573.1\|3953689_3953971_-	hypothetical protein	NA	NA	NA	NA
WP_025220574.1\|3954060_3954381_-	hypothetical protein	NA	NA	NA	NA
WP_052599537.1\|3954419_3954890_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_025220576.1\|3954926_3955124_-	hypothetical protein	NA	NA	NA	NA
WP_025220577.1\|3955162_3955702_-	hypothetical protein	A0A218KCM5	Bacillus_phage	5.7e-08	39.7
WP_025220578.1\|3955713_3955908_-	hypothetical protein	NA	NA	NA	NA
WP_137036945.1\|3955947_3956238_-	hypothetical protein	NA	NA	NA	NA
WP_025220580.1\|3956244_3956559_-	hypothetical protein	NA	NA	NA	NA
WP_025220581.1\|3956558_3956780_-	hypothetical protein	A0A2D1GQB9	Lysinibacillus_phage	1.2e-09	49.2
WP_025220582.1\|3956776_3957319_-	Holliday junction resolvase RecU	S5MCC4	Brevibacillus_phage	1.9e-19	37.4
WP_025220583.1\|3957350_3957608_-	hypothetical protein	NA	NA	NA	NA
WP_025220584.1\|3957635_3958607_-	DUF3850 domain-containing protein	H7BUL7	unidentified_phage	1.6e-21	33.5
WP_025220585.1\|3958642_3959404_-	ParA family protein	H7BUL8	unidentified_phage	2.6e-43	38.0
WP_025220586.1\|3959381_3960302_-	hypothetical protein	H7BW41	unidentified_phage	1.5e-21	32.9
WP_167331270.1\|3960571_3960727_-	hypothetical protein	Q2I8D2	Bacillus_phage	2.6e-06	42.0
WP_025220587.1\|3960859_3961213_-	hypothetical protein	NA	NA	NA	NA
WP_025220588.1\|3961209_3961500_-	hypothetical protein	NA	NA	NA	NA
WP_025220589.1\|3961799_3962126_-	DUF771 domain-containing protein	U3PBP3	Staphylococcus_phage	3.0e-12	44.3
WP_158497909.1\|3962146_3962320_-	hypothetical protein	NA	NA	NA	NA
WP_025220590.1\|3962451_3962868_+	helix-turn-helix transcriptional regulator	A0A0A8WEL4	Clostridium_phage	1.0e-09	44.0
WP_025220591.1\|3963338_3964442_+\|integrase	site-specific integrase	Q5YAA6	Bacillus_phage	5.8e-116	57.7
3964589:3964607	attR	NA	NA	NA	NA

DBSCAN-SWA_8

4140747 : 4149290

Bacillus_virus(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024363980.1\|4140747_4141572_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	5.9e-73	54.2
WP_024363979.1\|4141587_4143057_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	7.2e-114	46.1
WP_024363978.1\|4143368_4143710_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_024363977.1\|4143723_4145019_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	2.8e-69	40.3
WP_025220671.1\|4145112_4145613_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	2.4e-21	48.7
WP_025220672.1\|4145732_4146464_+	phosphate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.3e-18	30.5
WP_025220673.1\|4146460_4147213_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_024363973.1\|4147288_4148263_+	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	6.9e-89	51.5
WP_024363972.1\|4148573_4149290_-	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	9.1e-46	77.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP006837

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection