CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_HG813248	Listeria monocytogenes R479a plasmid pLMR479a, complete sequence	0 crisprs	csa3	0	0	0	0
NZ_HG813247	Listeria monocytogenes R479a	3 crisprs	DinG,cas3,WYL,casR,DEDDh,csa3	2	10	7	2

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_HG813247_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_HG813247_1

213340-213491

Unclear

Consensus_repeat	Method
CCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCAGAACCGAGCTC	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_HG813247_1

>merge|NZ_HG813247|1|213340-213491|CRISPRCasFinder
CCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCAGAACCGAGCTCATTCGAATTTCCACCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGACGCCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCGGAACCGAGCTC

>NZ_HG813247|1|1|213340-213491|CRISPRCasFinder
CCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCAGAACCGAGCTC	ATTCGAATTTCCACCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGACG
CCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCGGAACCGAGCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_HG813247.1\|WP_012952055.1\|210765_212298_+\|zinc-metalloproteinase-Mpl	unknown	unknown	gnl\|CDD\|225768
NZ_HG813247.1\|WP_003722731.1\|208845_210435_+\|cholesterol-dependent-cytolysin-listeriolysin-O	unknown	unknown	gnl\|CDD\|366559
NZ_HG813247.1\|WP_003722740.1\|218747_219371_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_HG813247.1\|WP_012952052.1\|215850_216312_+\|YehR-family-lipoprotein	unknown	unknown	gnl\|CDD\|227145
NZ_HG813247.1\|WP_003722723.1\|200538_201231_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_HG813247.1\|WP_009930499.1\|216761_217436_-\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|378033
NZ_HG813247.1\|WP_003722725.1\|203120_203429_+\|septation-regulator-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_HG813247.1\|WP_003722739.1\|217512_218454_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|178836
NZ_HG813247.1\|WP_003722728.1\|205667_206624_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_HG813247.1\|WP_010989376.1\|220826_224366_+\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118
NZ_HG813247.1\|WP_003733966.1\|214451_215321_+\|phosphatidylcholine-phospholipase-C	unknown	unknown	gnl\|CDD\|214813
NZ_HG813247.1\|WP_012952051.1\|219460_220045_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_HG813247.1\|WP_012952056.1\|207650_208604_-\|phosphatidylinositol-specific-phospholipase-C	unknown	unknown	gnl\|CDD\|176497
NZ_HG813247.1\|WP_003722735.1\|215392_215716_+\|DUF5502-family-protein	unknown	unknown	gnl\|CDD\|340321
NZ_HG813247.1\|WP_003722742.1\|220151_220712_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_HG813247.1\|WP_009931069.1\|201227_202436_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NZ_HG813247.1\|WP_003722726.1\|203548_203857_+\|septation-regulator-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_HG813247.1\|WP_003725735.1\|216362_216695_-\|putative-heavy-metal-binding-protein	unknown	unknown	gnl\|CDD\|179228
NZ_HG813247.1\|WP_003722727.1\|204243_205617_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl\|CDD\|184643
NZ_HG813247.1\|WP_003722729.1\|206666_207380_-\|listeriolysin-O-transcriptional-regulator-PrfA	unknown	unknown	gnl\|CDD\|223736

Protein	Function_ID	Function_description	E-value
NZ_HG813247.1\|WP_012952055.1\|210765_212298_+\|zinc-metalloproteinase-Mpl	gnl\|CDD\|225768	COG3227, LasB, Zinc metalloprotease (elastase) [Amino acid transport and metabolism].	9.42667e-139
NZ_HG813247.1\|WP_003722731.1\|208845_210435_+\|cholesterol-dependent-cytolysin-listeriolysin-O	gnl\|CDD\|366559	pfam01289, Thiol_cytolysin, Thiol-activated cytolysin.	1.50399e-178
NZ_HG813247.1\|WP_003722740.1\|218747_219371_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	2.38585e-63
NZ_HG813247.1\|WP_012952052.1\|215850_216312_+\|YehR-family-lipoprotein	gnl\|CDD\|227145	COG4808, COG4808, Uncharacterized protein conserved in bacteria [Function unknown].	1.58576e-57
NZ_HG813247.1\|WP_003722723.1\|200538_201231_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	7.27113e-121
NZ_HG813247.1\|WP_009930499.1\|216761_217436_-\|DNA-alkylation-repair-protein	gnl\|CDD\|378033	pfam08713, DNA_alkylation, DNA alkylation repair enzyme. Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alpha helical structure.	1.81561e-21
NZ_HG813247.1\|WP_003722725.1\|203120_203429_+\|septation-regulator-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	2.92652e-53
NZ_HG813247.1\|WP_003722739.1\|217512_218454_-\|L-lactate-dehydrogenase	gnl\|CDD\|178836	PRK00066, ldh, L-lactate dehydrogenase; Reviewed.	0
NZ_HG813247.1\|WP_003722728.1\|205667_206624_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_HG813247.1\|WP_010989376.1\|220826_224366_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NZ_HG813247.1\|WP_003733966.1\|214451_215321_+\|phosphatidylcholine-phospholipase-C	gnl\|CDD\|214813	smart00770, Zn_dep_PLPC, Zinc dependent phospholipase C (alpha toxin). This domain conveys a zinc dependent phospholipase C activity (EC 3.1.4.3). It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridium bifermentans, which is involved in haemolysis and cell rupture. It is also found in a lecithinase of Listeria monocytogenes, which is involved in breaking the 2-membrane vacuoles that surround the bacterium. Structure information: PDB 1ca1.	6.00128e-87
NZ_HG813247.1\|WP_012952051.1\|219460_220045_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	9.33654e-10
NZ_HG813247.1\|WP_012952056.1\|207650_208604_-\|phosphatidylinositol-specific-phospholipase-C	gnl\|CDD\|176497	cd00137, PI-PLCc, Catalytic domain of prokaryotic and eukaryotic phosphoinositide-specific phospholipase C. This subfamily corresponds to the catalytic domain present in prokaryotic and eukaryotic phosphoinositide-specific phospholipase C (PI-PLC), which is a ubiquitous enzyme catalyzing the cleavage of the sn3-phosphodiester bond in the membrane phosphoinositides (phosphatidylinositol, PI; Phosphatidylinositol-4-phosphate, PIP; phosphatidylinositol 4,5-bisphosphate, PIP2) to yield inositol phosphates (inositol monosphosphate, InsP; inositol diphosphate, InsP2; inositol trisphosphate, InsP3) and diacylglycerol (DAG). The higher eukaryotic PI-PLCs (EC 3.1.4.11) have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains. They play a critical role in most signal transduction pathways, controlling numerous cellular events, such as cell growth, proliferation, excitation and secretion. These PI-PLCs strictly require Ca2+ for their catalytic activity. They display a clear preference towards the hydrolysis of the more highly phosphorylated PI-analogues, PIP2 and PIP, to generate two important second messengers, InsP3 and DAG. InsP3 triggers inflow of calcium from intracellular stores, while DAG, together with calcium, activates protein kinase C, which then phosphorylates other molecules, leading to altered cellular activity. In contrast, bacterial PI-PLCs contain a single catalytic domain. Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. They participate in Ca2+-independent PI metabolism. They are characterized as phosphatidylinositol-specific phospholipase C (EC 4.6.1.13) that selectively hydrolyze PI, not PIP or PIP2. The TIM-barrel type catalytic domain in bacterial PI-PLCs is very similar to the one in eukaryotic PI-PLCs, in which the catalytic domain is assembled from two highly conserved X- and Y-regions split by a divergent linker sequence. The catalytic mechanism of both prokaryotic and eukaryotic PI-PLCs is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This superfamily also includes a distinctly different type of eukaryotic PLC, glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC), an integral membrane protein characterized in the protozoan parasite Trypanosoma brucei. T. brucei GPI-PLC hydrolyzes the GPI-anchor on the variant specific glycoprotein (VSG), releasing dimyristyl glycerol (DMG), which may facilitate the evasion of the protozoan to the host#s immune system. It does not require Ca2+ for its activity and is more closely related to bacterial PI-PLCs, but not mammalian PI-PLCs.	6.12448e-116
NZ_HG813247.1\|WP_003722735.1\|215392_215716_+\|DUF5502-family-protein	gnl\|CDD\|340321	pfam17606, DUF5502, Family of unknown function (DUF5502). This is a family of unknown function found in Listeria.	5.76244e-49
NZ_HG813247.1\|WP_003722742.1\|220151_220712_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	4.98809e-109
NZ_HG813247.1\|WP_009931069.1\|201227_202436_+\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	2.47504e-62
NZ_HG813247.1\|WP_003722726.1\|203548_203857_+\|septation-regulator-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	5.03804e-54
NZ_HG813247.1\|WP_003725735.1\|216362_216695_-\|putative-heavy-metal-binding-protein	gnl\|CDD\|179228	PRK01119, PRK01119, putative heavy metal-binding protein.	8.98192e-61
NZ_HG813247.1\|WP_003722727.1\|204243_205617_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl\|CDD\|184643	PRK14354, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NZ_HG813247.1\|WP_003722729.1\|206666_207380_-\|listeriolysin-O-transcriptional-regulator-PrfA	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	9.59942e-12

>NZ_HG813247.1|WP_012952055.1|210765_212298_+|zinc-metalloproteinase-Mpl
MKSKLICIIMVIAFQAHFTMTVKADSVGEEKLQNNTQAKKTPADLKALPDSCEAKDFYKNFKILDMTKDKLGVTHYTLALSSGGYLTDNDEIKVHVTPDNKITFINGDLQQGQLRITNQIKITEKNAIEKAFEAIGQSEAHVKSYVGNPVKEKEIILNSRTKRLVYNIKLIFAEPEVASWIVQVDVETGAILKKQNMLSEVERADTHKDFQALGKGANRLLQRPLHVMKINDLFYLVDRTHKGLIRTFDLKHNTDTSFGKVVSNKTNMFTDPEFSSAVDAHFYASEVYEYYKNVHQLESLDGKGGEIDSFVHYGLNCNNAFWDGQEILYGDGDKKNFKPFSCAKTIVGHELTHAVIQYSAGLEYEGQSGALNESFADVFGYFIAPNHWLIGEDVCVRGSRDGRIRSIKDPDKYNQAAHMKDYESLPITEEGDWGGVHYNSGIPNKAAYNTITKLGKEKTEQLYFRALKYYLTKKSQFTDAKKALQQAAKDLYGEDASKKVAEAWEAVGVN
>NZ_HG813247.1|WP_003722731.1|208845_210435_+|cholesterol-dependent-cytolysin-listeriolysin-O
MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE
>NZ_HG813247.1|WP_012952056.1|207650_208604_-|phosphatidylinositol-specific-phospholipase-C
MYKIYLRRTLVLVLCFILCFFTFPLGGKAYSLNNWNKPIKNSVTTKQWMSALPDTTNLAALSIPGTHDTMSYNGDITWTLTKPLAQTQTMSLYQQLEAGIRYIDIRAKDNLNIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKILLLSENHTKKPLVINSRKFGMQFGAPNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLTFTPRQYAAALNNKVEQFVLNLTSEKVRGLGILIMDFPEKQTIKNIIKNNKFN
>NZ_HG813247.1|WP_003722729.1|206666_207380_-|listeriolysin-O-transcriptional-regulator-PrfA
MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDGIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN
>NZ_HG813247.1|WP_003722728.1|205667_206624_+|ribose-phosphate-diphosphokinase
MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNAVRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEESPIEKLVVTNSIALPEEKWIDKMEQLSVAALLGEAIVRVHENASVSSLFE
>NZ_HG813247.1|WP_003722727.1|204243_205617_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MSKRYAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDQISTLNVDKVVTIVGHGAEKVQEHLAGKSEFVKQDEQLGTAHAVLQAKAELAGKDGVTLVVCGDTPLIEASTMEALLKYHHEKRAKATILTTVIEDPTGYGRIIRDDLGIVEKIVEHKDATEKEQRISEINTGTYCFDNKALFEALENVSNDNVQGEYYLPDVIKILKDSDEVVAAYRMESFEESLGVNDRIALAEASKLMQRRINENHMRNGVTLVNPESTYIDIDVKIGQDTVIEPGVMLRGKTVIGDDCVVTSGSEIVNSVIGERVHVRTSSIFESKVGDDVQIGPYAHLRPESDIHDHVKIGNYVETKKAVVGEGTKLPHFIYMGDAEIGKNVNVGCGSIAVNYDGKNKAKTIIGDNVFVGCNSNLIAPVKVGDRAFIAAGSTITKDVPEDALGIARAKQDNKLGYAKHLNHGK
>NZ_HG813247.1|WP_003722726.1|203548_203857_+|septation-regulator-SpoVG
MQVTDVRLRRVETDGRMRAIASITLDEEFVVHDIRVIDGNNGLFVAMPSKRGVDGEFRDIAHPINSDTRAKIQEVVLAEYERVGEEEATAVTEEESESVSAE
>NZ_HG813247.1|WP_003722725.1|203120_203429_+|septation-regulator-SpoVG
MEITDVRLRRVETDGRMKAISSITIDGEFVIHDIRVIDGNEGLFVAMPSKRTPDGEFRDIAHPINSGTRAKIQEAVLAAYEVADEPAVNEESSADESIVEEN
>NZ_HG813247.1|WP_009931069.1|201227_202436_+|ABC-transporter-permease
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNLITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYKAARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGDPIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGDEKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGVIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
>NZ_HG813247.1|WP_003722723.1|200538_201231_+|ABC-transporter-ATP-binding-protein
MPKPLIDMKNLTKTYTLGGETFKALDDVTFTVEQGEFLSIVGPSGSGKSTLMNMIGCLDVPDEGSYHLDDVDVFKLSDNKLSEIRNKKIGFIFQQFNLLPKLSAFENVELPLIYAGLSVSAREKAAIECLEKVGLLEKRRNLPTQLSGGQQQRVAIARALAGKPQILLADEPTGALDSKTGKEVMGILQELNRAGNTIVMITHDPTIASYGTRSIRIQDGKLFHEEATQA
>NZ_HG813247.1|WP_003733966.1|214451_215321_+|phosphatidylcholine-phospholipase-C
MKFKKVVLGMCLTASVLVFPVTIKANACCDEYLQTPAAPHDIDSKLPHKLSWSADNPTNTDVNTHYWLFKQAEKILAKDVNHMRANLMNELKKFDKQIAQGIYDADHKNPYYDTSTFLSHFYNPDRDNTYLPGFANAKITGAKYFNQSVTDYREGKFDTAFYKLGLAIHYYTDISQPMHANNFTAISYPPGYHCAYENYVDTIKHNYQATEDMVAKRFCSDDVKDWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKKDTVEPTGARLRDSQQTLAGFLEFWSKKTNE
>NZ_HG813247.1|WP_003722735.1|215392_215716_+|DUF5502-family-protein
MYIKGRLIFFFVMFVIALCSVLILLIIKISVWKDEPFHLSDAKEIECLGSCEIKNTNQKIHFFSIKENLFEEKGDIAGILNEDEQKVADKSIFIVILDDEKGIANEE
>NZ_HG813247.1|WP_012952052.1|215850_216312_+|YehR-family-lipoprotein
MKMLKKGTAVLFVMIMAVMLVACGDKEETKTYTLSQKGVDSKLTYTYKGDKVTKQTAENTMSYASLGVASKEDAEKMLKATSDKFQGIDGLKEKIEYKDDKAIETLEVDYTKISSEDMNKIPGMSSNGDTSKGISMEESAKMLESQGYKEVSK
>NZ_HG813247.1|WP_003725735.1|216362_216695_-|putative-heavy-metal-binding-protein
MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMEQRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEAQDY
>NZ_HG813247.1|WP_009930499.1|216761_217436_-|DNA-alkylation-repair-protein
MITFDQLDTELQALENPNTIKIFRNHGCPDSLDLYGLKIGDLKKIIRREKLTKNHELAVKLIESNNSDLIYLGLLAINPNKITTEQIEKWNIAFRETWSQLTFGLASIVSKRDDALLFAKTWIESDYDLTKSMGWQIYSEHINNLPEAETLLQRAKETLQTETNRTRYSMNGFIITCGIYKDDLHEKAMEAAKSVGKVHVNLGNTACKVPDAISYIEKARNRTK
>NZ_HG813247.1|WP_003722739.1|217512_218454_-|L-lactate-dehydrogenase
MKDHQKIILVGDGAVGSSYAFACVNLSIGQEFGIIDIDKDRTIGDAMDLSHAVPFSTPKKIYSANYSDCHDADLVVVTAGTAQKPGETRLDLVNRNIKIMKGIVDEVMASGFDGIFLIASNPVDILTYATWKFSGLPKERVIGSGTSLDTARFRMSIADYLKVDARNVHGYILGEHGDTEFPAWSHTTVGGLPITEWISEDEQGAMDTIFVSVRDAAYEIINKKGATFYGVAAALARITKAILNNENAILPLSVYLDGHYGMNDIYIGAPAVVNRQGVRHIVEMNLNDKEKEQMKNSADTLKKVLDDAMKQID
>NZ_HG813247.1|WP_003722740.1|218747_219371_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MATTLEVQKRETTQHSEVTRLRSEGKVPGIIYGYKSENVPVSVDSLELIKAVRDNGRNAVFSVTVDGKKLNVLLHEYQVDPLKDVLVHVDLLAVDMNEEVETDVRVVLVGDAPGVKAGGVLQQIIHDVKVSATPEKLPETIELDISSLEIGDVLTTNDLPENKDYVVQAEEEETVVTVSAPRAEEEPTTTEAPEPEAVHGKDEEPVE
>NZ_HG813247.1|WP_012952051.1|219460_220045_+|GNAT-family-N-acetyltransferase
MLDKSVPHISVIMVNHDATNYPEFHLPAGYFFCFYKDGLEEDWCRLQLETGQVLSMDSIRARFETEFGNEKEKLTKRCIFVKAPNGEIIGTAMLWDGNTFGKMESRIHWVAVLDSHGGKGIAKALLSKILGLNKSKFVYLTTQTGSYQAIYLYRKFGFEKYVGKTPENWKTVNFQEEKETAWQIIENKIAEHQA
>NZ_HG813247.1|WP_003722742.1|220151_220712_+|aminoacyl-tRNA-hydrolase
MKLIAGLGNPGKKYERTRHNVGFMVVDELSFRHQTPWKKSKFNGMTSEIIVGGEKMILVKPLTFMNASGECIRPLMDYYNIPIEDVVIVYDDLDLPVGKIRLRQKGSAGGHNGMKSIIQHVKTQEFNRIRVGVSRPLKGEVINYVLGDFPKAEQPDIIAAIQKSADAIEDFAQTPFIEVMNKYNQK
>NZ_HG813247.1|WP_010989376.1|220826_224366_+|transcription-repair-coupling-factor
MKGLQQLIYEQKDIRAVLNALDEKEKAQLVTGLTGSSRALFASVVEGASKRPVVFVTHNLYHAQKLYDDLLSLMDVDRLFLYPADELISSELSISSPELRGQRVEALDFLLSGKPGIVIVPVAGLRKMLPPVSLWKHFNISIVEGEEIDPDVLRQKLVTMGYTMSGMVNTPGEFSVRGGIIDIYPITEEFPIRIELFDTEVDSLRFFDVETQRSTTRVEEFRLLPATEIILDQSYYPDIVKRLEKKMMLTLNELKEQEDKQALIENLEEDLEMLRSGVKPDMFFKYIGLAYPDPASLFDYLPKNTAILLDEFGRILETEESLEREEAEWQTETLSRMETVRDVQVSHSFKKLLEGNHSPKIYLSLFQKQMASMRVSKTTNIVYKQMQQFHGQMNVLKTELESWHKNNYAVVILAPNLERAEKMQQTLTDYDMESTILKKESDVPKYGMVQFVIGTFQNGFELPLAKVAIISETELFNKKIKKVKKRQKLSNAERIQSYSELKVGDYVVHVNHGIARYVGMETLDINGVHKDYLLLVYQGEDKLFIPVDQLDLVQKYVGAEGKSPRLNKLGGAEWKRVKKKVQASVQDIADDLIKLYAEREAEKGYAFSADDEMQREFEEAFPYQETEDQLRSISEIKKDMERPRPMDRLLVGDVGYGKTEVALRAAFKAIMDGKQVAFLVPTTILAQQHFETMKERFQGFPIEIGLLSRFRTKKQQTETLKGMKNGTVDVVVGTHRLLSKDVEYQDLGLLIVDEEQRFGVTHKEKIKQMRSKIDVLTLTATPIPRTLHMSMLGVRDLSVIETPPANRFPVQTYVAEQNNVLVREAIERELARDGQVYYLYNRVESITQKADEISAMVPDARVATAHGQMGESELESVILSFLEGEFDVLVTTTIIETGVDIPNVNTLFVQDADRMGLSQLYQLRGRVGRWNRIAYAYFMYQKDKILREEAEKRLSAIKEFTELGSGFKIAMRDLSIRGAGNILGAQQHGFIDSVGFDLYSQMLKEAIEAKKPKEEQKQIVPVEIDIQADAYIPEYYITDGRQKIEMYKRFRNIETLSELEDLQSDMIDRFGEYPEEVEYLFTMTELKVRALEVGIESVKQEQNKITMLFSESGTAGIRGDIVMQIIGEFGRMVGVGMEGTQLKITINVQNKPLKEWLYQVKSLAEKLRGAMKEKASTEN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_HG813247_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_HG813247_2

515168-515645

Orphan

I-A

Consensus_repeat	Method
GTTTTAGTTACTTATTGTGAAATGTAAAT	PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAAT	CRT
TTTTAGTTACTTATTGTGAAATGTAAAT	CRISPRCasFinder

7 spacers

The CRISPR arrays of NZ_HG813247_2

>merge|NZ_HG813247|2|515168-515645|PILER-CR,CRT,CRISPRCasFinder
GTTTTAGTTACTTATTGTGAAATGTAAATACAGATCAAACTCCGGAAGGGTGATTGTAAATGGCGTTTTAGTTACTTATTGTGAAATGTAAATTGCTCTCTTTTGTGTAAAGCACATCAAGCATGTAGCGTTTTAGTTACTTATTGTGAAATGTAAATGCGATTTTTGTCAAAGGGACAGCGATGGGTTACAAGTTTTAGTTACTTATTGTGAAATGTAAATTTTTCTACTCCTGCTTCTAAAATGTCGTTTATAAGTTTTAGTTACTTATTGTGAAATGTAAATCTAAAACATCCTTCACTGTATCAACTCCTTTCTATATTTTAGTTACTTATTGTGAAATGTAAATAAAATAGGAGGAAATAAATTATGACTATCAAATTAAGTTTTAGTTACTTATTGTGAAATGTAAATTTTGTTGAATCAACGGATATAGATTTTACAATTTCGTTTTAGTTACTTATTGTGAAATGTAAAT

>NZ_HG813247|2|1|515168-515645|PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAAT	ACAGATCAAACTCCGGAAGGGTGATTGTAAATGGC
GTTTTAGTTACTTATTGTGAAATGTAAAT	TGCTCTCTTTTGTGTAAAGCACATCAAGCATGTAGC
GTTTTAGTTACTTATTGTGAAATGTAAAT	GCGATTTTTGTCAAAGGGACAGCGATGGGTTACAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTTCTACTCCTGCTTCTAAAATGTCGTTTATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTAT
ATTTTAGTTACTTATTGTGAAATGTAAAT	AAAATAGGAGGAAATAAATTATGACTATCAAATTAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTGTTGAATCAACGGATATAGATTTTACAATTTC
GTTTTAGTTACTTATTGTGAAATGTAAAT

>NZ_HG813247|2|1|515168-515645|CRT
GTTTTAGTTACTTATTGTGAAATGTAAAT	ACAGATCAAACTCCGGAAGGGTGATTGTAAATGGC
GTTTTAGTTACTTATTGTGAAATGTAAAT	TGCTCTCTTTTGTGTAAAGCACATCAAGCATGTAGC
GTTTTAGTTACTTATTGTGAAATGTAAAT	GCGATTTTTGTCAAAGGGACAGCGATGGGTTACAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTTCTACTCCTGCTTCTAAAATGTCGTTTATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTAT
ATTTTAGTTACTTATTGTGAAATGTAAAT	AAAATAGGAGGAAATAAATTATGACTATCAAATTAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTGTTGAATCAACGGATATAGATTTTACAATTTC
GTTTTAGTTACTTATTGTGAAATGTAAAT

>NZ_HG813247|2|2|515169-515645|CRISPRCasFinder
TTTTAGTTACTTATTGTGAAATGTAAAT	ACAGATCAAACTCCGGAAGGGTGATTGTAAATGGCG
TTTTAGTTACTTATTGTGAAATGTAAAT	TGCTCTCTTTTGTGTAAAGCACATCAAGCATGTAGCG
TTTTAGTTACTTATTGTGAAATGTAAAT	GCGATTTTTGTCAAAGGGACAGCGATGGGTTACAAG
TTTTAGTTACTTATTGTGAAATGTAAAT	TTTTCTACTCCTGCTTCTAAAATGTCGTTTATAAG
TTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTATA
TTTTAGTTACTTATTGTGAAATGTAAAT	AAAATAGGAGGAAATAAATTATGACTATCAAATTAAG
TTTTAGTTACTTATTGTGAAATGTAAAT	TTTGTTGAATCAACGGATATAGATTTTACAATTTCG
TTTTAGTTACTTATTGTGAAATGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_HG813247.1\|WP_003727295.1\|524208_525624_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_HG813247.1\|WP_012951247.1\|516036_516615_+\|hypothetical-protein	unknown	unknown	unknown
NZ_HG813247.1\|WP_003721301.1\|520568_521000_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_HG813247.1\|WP_003721294.1\|512583_513855_+\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
NZ_HG813247.1\|WP_012951250.1\|518632_520468_+\|lmo0514-family-class-1-internalin	unknown	unknown	gnl\|CDD\|380190
NZ_HG813247.1\|WP_003733187.1\|517792_518251_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
NZ_HG813247.1\|WP_003721290.1\|510157_510556_+\|hypothetical-protein	unknown	unknown	unknown
NZ_HG813247.1\|WP_012951246.1\|511213_512260_+\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198
NZ_HG813247.1\|WP_012951251.1\|521046_522477_-\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NZ_HG813247.1\|WP_014601718.1\|517426_517786_-\|Lin0512-family-protein	unknown	unknown	gnl\|CDD\|131113
NZ_HG813247.1\|WP_003733193.1\|506979_509040_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_HG813247.1\|WP_003721297.1\|516721_517402_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153212
NZ_HG813247.1\|WP_003721303.1\|522597_523413_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_HG813247.1\|WP_003721293.1\|512275_512569_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NZ_HG813247.1\|WP_003733190.1\|513994_514930_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_HG813247.1\|WP_012951252.1\|523693_524062_-\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|226282
NZ_HG813247.1\|WP_012951245.1\|510566_511217_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NZ_HG813247.1\|WP_012951243.1\|506220_506871_+\|transaldolase	unknown	unknown	gnl\|CDD\|223254
NZ_HG813247.1\|WP_003733192.1\|509043_509646_+\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223865
NZ_HG813247.1\|WP_003733191.1\|509673_510141_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129

Protein	Function_ID	Function_description	E-value
NZ_HG813247.1\|WP_003727295.1\|524208_525624_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.97112e-80
NZ_HG813247.1\|WP_012951252.1\|523693_524062_-\|DUF1304-domain-containing-protein	gnl\|CDD\|226282	COG3759, COG3759, Predicted membrane protein [Function unknown].	8.73125e-42
NZ_HG813247.1\|WP_003721301.1\|520568_521000_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.03126e-27
NZ_HG813247.1\|WP_003721294.1\|512583_513855_+\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	7.01085e-178
NZ_HG813247.1\|WP_012951250.1\|518632_520468_+\|lmo0514-family-class-1-internalin	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	8.58129e-120
NZ_HG813247.1\|WP_003733187.1\|517792_518251_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	1.03599e-12
NZ_HG813247.1\|WP_012951246.1\|511213_512260_+\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	0
NZ_HG813247.1\|WP_012951251.1\|521046_522477_-\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	7.01384e-100
NZ_HG813247.1\|WP_014601718.1\|517426_517786_-\|Lin0512-family-protein	gnl\|CDD\|131113	TIGR02058, lin0512_fam, conserved hypothetical protein. This family consists of few members, broadly distributed. It occurs so far in several Firmicutes (twice in Oceanobacillus), one Cyanobacterium, one alpha Proteobacterium, and (with a long prefix) in plants. The function is unknown. The alignment includes a perfectly conserved motif GxGxDxHG near the N-terminus. [Hypothetical proteins, Conserved].	4.36834e-66
NZ_HG813247.1\|WP_003733193.1\|506979_509040_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	3.95572e-80
NZ_HG813247.1\|WP_003721297.1\|516721_517402_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|153212	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	7.71833e-60
NZ_HG813247.1\|WP_003721303.1\|522597_523413_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.01016e-50
NZ_HG813247.1\|WP_003721293.1\|512275_512569_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.06007e-27
NZ_HG813247.1\|WP_003733190.1\|513994_514930_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	1.26262e-153
NZ_HG813247.1\|WP_012951245.1\|510566_511217_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	8.25352e-108
NZ_HG813247.1\|WP_012951243.1\|506220_506871_+\|transaldolase	gnl\|CDD\|223254	COG0176, MipB, Transaldolase [Carbohydrate transport and metabolism].	1.0547e-61
NZ_HG813247.1\|WP_003733192.1\|509043_509646_+\|SIS-domain-containing-protein	gnl\|CDD\|223865	COG0794, GutQ, Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane].	1.15952e-75
NZ_HG813247.1\|WP_003733191.1\|509673_510141_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	2.76446e-37

>NZ_HG813247.1|WP_003733190.1|513994_514930_+|ribose-phosphate-pyrophosphokinase
MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGNATERLQNSNIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
>NZ_HG813247.1|WP_003721294.1|512583_513855_+|PTS-galactitol-transporter-subunit-IIC
MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVITSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAFKWTKTMDVDIWNYWQPLFIASALYLTTGSMIIAVLSSIINMAIIFKIADWTQKDVEDVLGLEGISLPQIQTTGWALVGYPMNWLLGKIPGVRKINWSTEKVQSRLGIFGEPMLMGLIIGGGLAAIAQMPLSQVLQTGVTIAASLVLIPRMVSLLMDGLTVISEAAHEFMEKRFPGRELFIGLDSAVGIGHPFVLSLGLLMIPITLILAFILPGNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGAAAPLMTELAGQIGYNIPKDAVEVTSLAVGTQWYTWIVYYGLHWFGGIL
>NZ_HG813247.1|WP_003721293.1|512275_512569_+|PTS-sugar-transporter-subunit-IIB
MKKKRIYVCCGTGIATSTVISKKVRAVLDEKRIPYEISQCTVQEVASKVSTSKPDIIVSSTTVTGDVGDVPVVIGRSFLTGLKKQETIDEILAILQD
>NZ_HG813247.1|WP_012951246.1|511213_512260_+|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGKRDLRYEEADMPTIEEPDDVILKVKTVGICGSDISRYSKLGPYVPGMVWGHEFSGEVIEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHPGAYAEYIKLPAENVVKIPDELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVFGARRVIAIDVDDKKLALAKEVGADVVINSLKEDPLEVVAAHTDGLNADLVVEAAGSPITSAQVFAYAKKGGGVVFLGIPYADVTIERFYFEKIVRSELTVWGSWNAISAPFPGKEWQTTIHFLANKQINIEPMITHRLSLAEGPEVFERIYERNEFFGKILFFPE
>NZ_HG813247.1|WP_012951245.1|510566_511217_+|ribulose-phosphate-3-epimerase
MAKIVPSVFGADIGRINEQLQVLEKNDIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNAELAKECTLAGADLIVVGSYLFEGDIEANLEKLAKGVLTE
>NZ_HG813247.1|WP_003721290.1|510157_510556_+|hypothetical-protein
MGSFFASFVDWLIGSPGRFVVNLIEDNMLIFMVVVMIYATTILYAKWTLAYYLPKKMSQLAEMKTWELDELYAAWQTEKKALPWYILVPSRNEFWVKSARNAPESTKLLHFSQQKLKLSDKEKLQKIIEIQS
>NZ_HG813247.1|WP_003733191.1|509673_510141_+|PTS-sugar-transporter-subunit-IIA
MDVLEYFKEEMVRFSNEQNKEKLLAEMAEQLCEVGAVKPSYKDAVIKREKVFPTGLLTAHAGVAIPHTDSEHVIRPVVAVRILKKPVSFIEMASDNEAIDVRIVFMMALRSADEQLDMLQTLIQLIQDEEVMTTLLKAQETGDVLSAIEHFSKNN
>NZ_HG813247.1|WP_003733192.1|509043_509646_+|SIS-domain-containing-protein
MDKQAILNNIHQTWQEEANAISRLPEVTSEEALVKTVEKIAECTGKIVVAGCGTSGVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDILILISKGGNTGELLNLIPACKTKGSTLIGVTENPDSVIAKEADIFFPVSVSKEPDPFNMLATASTMAVIASFDAVIVCLMTYMNYTKEQFSVIHPGGAVGNKLLNK
>NZ_HG813247.1|WP_003733193.1|506979_509040_+|BglG-family-transcription-antiterminator
MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTSKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDEKSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVLQNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANTATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQILDDLLENVTKEKIMQTINQLVIREDE
>NZ_HG813247.1|WP_012951243.1|506220_506871_+|transaldolase
MHLDSANLDDVKKIQASSIFKGITTNPTILVKEKCNRQTAINRILELTDKQVFVQTVGFTYEEILADARMLLTMFGKDKIAIKIPAHEAGTNVIDTLKKEDKTIQILGTAIYSADQAITAALVGADFVAPYVNRMSAANIDPFKEIRQMRHFFDKKALKTQIMAASFKHSGQVMQAYESGADTVTIPYEIYLQMTNKVLAVEAIRVFNEDAVLYEK
>NZ_HG813247.1|WP_012951247.1|516036_516615_+|hypothetical-protein
MKKILVPILLLATILASCSSPNEKITKDTKISKTNTIRADYKVPKDIKELEDDSANIVKVKFLQNKTIGKDGSTISEIEILTSYKGNLEKGSKVDISEPWYLSDGKYVAVENYIALDKEQEYTIFLGEKDKDTYPLSSLGYGKFGGSLKEDQAVLADFNILGEVQKFDFISENTEEVKNYQLIKEQVAGKYK
>NZ_HG813247.1|WP_003721297.1|516721_517402_+|type-1-glutamine-amidotransferase
MIIDVLQHVPHEGPGLIANWARENQHQLKIHSLFEENAHVPNDSDFLIVLGGPMGINDTAEFPWLKDERKLIKRLSEQHKPVFGVCLGAQQIAATFGSEITVNKEKEVGWFPVKRTSDKLLFFPESLNVFHWHQDTFALPTGSTRLFASEGCLNQAFLYGENIIGLQFHFEMEKAGIETILRIDEAFITPGKYVQSVEVMREKDVPEDNKQMLEAILDYLINPKTI
>NZ_HG813247.1|WP_014601718.1|517426_517786_-|Lin0512-family-protein
MEQILFIQTGFGVDVHGQNITNAAERAVRNAIFTNSMPGIQGLLPDGDLQNMVVNIKLALPCDADQLDEDTIRAIIPYGTVTIEKMAGGMMTTSGIFLEDKEDKNDLMYIVNASVETGY
>NZ_HG813247.1|WP_003733187.1|517792_518251_-|MarR-family-transcriptional-regulator
MNNEQNMNQQIALFYFGYKAFTETADLIIAKHSLKRLHHRILFFTARMPGLTINELLTFLEISKQALHQPLAELKERELLTIEQGRRDKRQRCIFLTAAGKELENELGAAQRKQMSEIFTNSADTDGMHFTEVMEGYAKNRPGAAFIKDFKE
>NZ_HG813247.1|WP_012951250.1|518632_520468_+|lmo0514-family-class-1-internalin
MKKALKLFLATICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLEEAGNLVTLSLNNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSISGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSSRLSITDDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPTPPSMTSYTISSGTYDQYFDISHTLDLTADESFDYNQYDTTSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITSDSQISYKKETTKSVDEFLKEIHGSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAINDRGQKADPVTVVVTVTTSDSGHVDPVPPTPEIKPTPQEETDQTIIPEPQSETTEDSVKEDQAKDGQAKSEEKADKTSLTTKENKVEKSEKTNQPKTKALPQTGDTNKTALPIAGVMLSLAALLIFRKSKS
>NZ_HG813247.1|WP_003721301.1|520568_521000_+|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQADLIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>NZ_HG813247.1|WP_012951251.1|521046_522477_-|CapA-family-protein
MKKLTYVIITGLVLVFIAGAFWITNSTNQSDQKATQTEPIKKISPANVKTISSEAKKTLNSLASSGADKASISDLKQLIKELKSYPTEKNDSGVYLQNLTACLEAVKSYTTGKTDEKTLGKVYPAFLASEQKLSAIEKTNQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFQKNNGNNTYVYKNCLPWFKSDDYTVINAESAFTNATKAENKKWRIKSDPAHVAFLPASGVDAANLANNHTMDYFQVGYDDTLKAFKENNIPVFNADAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTKEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIEGGVTEYTYFDPF
>NZ_HG813247.1|WP_003721303.1|522597_523413_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDPRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGLSPKDFANSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>NZ_HG813247.1|WP_012951252.1|523693_524062_-|DUF1304-domain-containing-protein
MAILAFILTFIVMIEHIYIMILEMFFANTKLAAKTFGVEKELLANKKVQTLFANQGLYNGFLAAGLVWGLFFAGAGMAETVQIFFLSCVVVAALFGGATSSKGILVKQGLPAVLALVAVLLV
>NZ_HG813247.1|WP_003727295.1|524208_525624_+|multidrug-efflux-MFS-transporter
MQQEATGGQKIRPIPIIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQWFTTRGLFFTAVSFSIAGTLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEHKRGSAMGMIGLVIMFAPAVGPTISGLILENLTWNWIFWISLPFLIIALLFGMKFMQNVSVVTKPKIDILSIILSTLGFGGVVFAFSSAGESGWGSATVLVSIIVGGLALGLFVWRQLTMEKPLMDLKVFKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPGGVLNGLMSPFTGRLFDAYGPRALVIPGFIVAVVALFFLTRIEVGTSALTIIVLHSVLMIGISMVMMPAQTNGLNQLPPKLYPDGTAIMNTLQQVSGAIGTAVAITIMSAGQKAYMETAQGVGPEQMVASLTAGIQNAFVFGLIMACIGLLCSLFIRKAK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_HG813247_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_HG813247_3

2782745-2782853

Orphan

Consensus_repeat	Method
AGAACTTTCAAAATGTACTTTATTTTGATTTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_HG813247_3

>merge|NZ_HG813247|3|2782745-2782853|CRISPRCasFinder
AGAACTTTCAAAATGTACTTTATTTTGATTTAGTTCTTCAATATAAATCTGAGCGCAGCGATGATTTAATCCTTCCCAGAACTTTCAAAATGTACTTTATTTTGATTTA

>NZ_HG813247|3|3|2782745-2782853|CRISPRCasFinder
AGAACTTTCAAAATGTACTTTATTTTGATTTA	GTTCTTCAATATAAATCTGAGCGCAGCGATGATTTAATCCTTCCC
AGAACTTTCAAAATGTACTTTATTTTGATTTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_HG813247.1\|WP_003728589.1\|2783459_2783642_-\|DUF3188-domain-containing-protein	unknown	unknown	gnl\|CDD\|371501
NZ_HG813247.1\|WP_009931159.1\|2778747_2779590_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|223729
NZ_HG813247.1\|WP_012951102.1\|2775737_2776334_+\|dihydroxyacetone-kinase-subunit-L	unknown	unknown	gnl\|CDD\|274099
NZ_HG813247.1\|WP_003728591.1\|2784000_2785365_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224372
NZ_HG813247.1\|WP_003732084.1\|2780947_2782687_-\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505
NZ_HG813247.1\|WP_003722061.1\|2779635_2779881_-\|YaaL-family-protein	unknown	unknown	gnl\|CDD\|378478
NZ_HG813247.1\|WP_003728590.1\|2783644_2783866_-\|hypothetical-protein	unknown	unknown	unknown
NZ_HG813247.1\|WP_003722065.1\|2782977_2783442_-\|DUF3284-domain-containing-protein	unknown	unknown	gnl\|CDD\|378692
NZ_HG813247.1\|WP_009925039.1\|2786534_2787176_-\|hypothetical-protein	unknown	unknown	unknown
NZ_HG813247.1\|WP_003732079.1\|2774726_2775716_+\|dihydroxyacetone-kinase-subunit-DhaK	unknown	unknown	gnl\|CDD\|237724
NZ_HG813247.1\|WP_003722062.1\|2779895_2780492_-\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NZ_HG813247.1\|WP_009913205.1\|2776337_2776712_+\|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM	unknown	unknown	gnl\|CDD\|184702
NZ_HG813247.1\|WP_009931588.1\|2785807_2785963_+\|hypothetical-protein	unknown	unknown	unknown
NZ_HG813247.1\|WP_003722073.1\|2789503_2790442_-\|GW-domain-containing-glycosaminoglycan-binding-protein	unknown	unknown	gnl\|CDD\|226309
NZ_HG813247.1\|WP_012951101.1\|2776817_2777669_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_HG813247.1\|WP_003722074.1\|2790484_2791432_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_HG813247.1\|WP_012951100.1\|2777787_2778627_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NZ_HG813247.1\|WP_003722063.1\|2780600_2780918_-\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NZ_HG813247.1\|WP_003732087.1\|2787873_2789388_-\|gluconokinase	unknown	unknown	gnl\|CDD\|212659
NZ_HG813247.1\|WP_003732089.1\|2791572_2793312_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320

Protein	Function_ID	Function_description	E-value
NZ_HG813247.1\|WP_003728589.1\|2783459_2783642_-\|DUF3188-domain-containing-protein	gnl\|CDD\|371501	pfam11384, DUF3188, Protein of unknown function (DUF3188). This bacterial family of proteins has no known function.	4.70726e-11
NZ_HG813247.1\|WP_009931159.1\|2778747_2779590_+\|aldo/keto-reductase	gnl\|CDD\|223729	COG0656, ARA1, Aldo/keto reductases, related to diketogulonate reductase [General function prediction only].	6.97706e-130
NZ_HG813247.1\|WP_012951102.1\|2775737_2776334_+\|dihydroxyacetone-kinase-subunit-L	gnl\|CDD\|274099	TIGR02365, dha_L_ycgS, dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.	1.69543e-82
NZ_HG813247.1\|WP_003728591.1\|2784000_2785365_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	1.91509e-162
NZ_HG813247.1\|WP_003732084.1\|2780947_2782687_-\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
NZ_HG813247.1\|WP_003722061.1\|2779635_2779881_-\|YaaL-family-protein	gnl\|CDD\|378478	pfam10704, DUF2508, Protein of unknown function (DUF2508). This family is conserved in Firmicutes. Several members are annotated as being the protein YaaL. The function is not known.	2.68189e-15
NZ_HG813247.1\|WP_003722065.1\|2782977_2783442_-\|DUF3284-domain-containing-protein	gnl\|CDD\|378692	pfam11687, DUF3284, Domain of unknown function (DUF3284). This family of proteins with unknown function appears to be restricted to Firmicutes.	5.35099e-31
NZ_HG813247.1\|WP_003732087.1\|2787873_2789388_-\|gluconokinase	gnl\|CDD\|212659	cd07770, FGGY_GntK, Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases. This subfamily is composed of a group of gluconate kinases (GntK, also known as gluconokinase; EC 2.7.1.12) encoded by the gntK gene, which catalyzes the ATP-dependent phosphorylation of D-gluconate and produce 6-phospho-D-gluconate and ADP. The presence of Mg2+ might be required for catalytic activity. The prototypical member of this subfamily is GntK from Lactobacillus acidophilus. Unlike Escherichia coli GntK, which belongs to the superfamily of P-loop containing nucleoside triphosphate hydrolases, members in this subfamily are homologous to glycerol kinase, xylulose kinase, and rhamnulokinase from Escherichia coli. They have been classified as members of the FGGY family of carbohydrate kinases, which contain two large domains separated by a deep cleft that forms the active site. This model spans both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. Some uncharacterized homologous sequences are also included in this subfamily. The Lactobacillus gnt operon contains a single gntK gene. The gnt operons of some bacteria, such as Corynebacterium glutamicum, have two gntK genes. For example, the C. glutamicum gnt operon has both a gluconate kinase gntV gene (also known as gntK) and a second hypothetical gntK gene (also known as gntK2). Both gluconate kinases encoded by these genes belong to this family, however the protein encoded by C. glutamicum gntV is not included in this model as it is truncated in the C-terminal domain.	0
NZ_HG813247.1\|WP_003732079.1\|2774726_2775716_+\|dihydroxyacetone-kinase-subunit-DhaK	gnl\|CDD\|237724	PRK14481, PRK14481, dihydroxyacetone kinase subunit DhaK; Provisional.	0
NZ_HG813247.1\|WP_003722062.1\|2779895_2780492_-\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	7.77001e-132
NZ_HG813247.1\|WP_009913205.1\|2776337_2776712_+\|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM	gnl\|CDD\|184702	PRK14484, PRK14484, phosphotransferase mannnose-specific family component IIA; Provisional.	2.28713e-49
NZ_HG813247.1\|WP_003732089.1\|2791572_2793312_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NZ_HG813247.1\|WP_003722073.1\|2789503_2790442_-\|GW-domain-containing-glycosaminoglycan-binding-protein	gnl\|CDD\|226309	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown].	6.39605e-99
NZ_HG813247.1\|WP_012951101.1\|2776817_2777669_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	3.97147e-62
NZ_HG813247.1\|WP_003722074.1\|2790484_2791432_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	1.13667e-05
NZ_HG813247.1\|WP_012951100.1\|2777787_2778627_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.59066e-84
NZ_HG813247.1\|WP_003722063.1\|2780600_2780918_-\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	3.53269e-41

>NZ_HG813247.1|WP_003732084.1|2780947_2782687_-|DNA-polymerase-III-subunit-gamma/tau
MAYQALYRVFRPQSFQDVVGQEHVTKTLKNAIVQNKTSHAYLFSGPRGTGKTSAAKIFAKAINCEHGHDGEPCNECEICKGTTDGSIPDVLEIDAASNNGVEEIRDIREKVKYAPTVAKYKVYIIDEVHMLSTGAFNALLKTLEEPPKHVIFILATTEPHKLPLTIISRVQRFDFKRITTQDIIGRLKFILEEEKIPYDEKALMIVARAAEGGMRDALSLLDQVISYGSEEVTVEDALEITGSVAQNLLTKLVSAAFDGDAAEAISTLTALLAEGKDPVRLVEDLLVFFRDVLLYQKAPNLEETMERALIDDDFVALAKRADSLKVYEFVKILNTAQQQMRFSNHPGIYVEVALVQLTQAGQSVAGGGNVPADAASGSDVSDLKRQMEQMHQEIQTLKKQIASGAGAAPADKPTQNRGGSKKAINNGKQFKAPIGKINHVLGEAKKENLQLIRGCWGELLSMLMASQAALLNDAEPVAASQDTFVLKFKHEIHCQMAMDNPNFVETITSSIARLTQVNYTFIGIPEDQWADVRENFLHSHGSDADAEDGANPEAKKPAEDPFVAEAAKLVGEDLLEIKD
>NZ_HG813247.1|WP_003722063.1|2780600_2780918_-|YbaB/EbfC-family-nucleoid-associated-protein
MRGMGNMQGMMKQMQKMQKEMAKAQADLEAQEFTGTAGGGMVTVKATGKRVITDVVINEEVVDPEDIEMLQDLVLAATNDVLKQIEDTTSQTMGKFTQGLNIPGM
>NZ_HG813247.1|WP_003722062.1|2779895_2780492_-|recombination-protein-RecR
MHYPEPITKLIDSFMKLPGIGPKSAARLAFYVLDMKEDDVLDFAKALVDAKRNLSFCSVCGHITDKDPCYICADTSRDRSVICVVQESKDVIAMEKMRDFHGLYHVLHGTISPMDGIGPEDINIPDLLKRLQDDTIEEVILATNPNVEGEATAMYISRLLKPSGIKVTRIAHGLPVGGDLEYADEVTLSKAMEGRREV
>NZ_HG813247.1|WP_003722061.1|2779635_2779881_-|YaaL-family-protein
MESRSNKFGRKKNKKIGKLHKSYDAYLMELIEVTQENWHKQKVLMRKSFEYDPNLEYEEKKAEARYFYLFKEARTRQLKNK
>NZ_HG813247.1|WP_009931159.1|2778747_2779590_+|aldo/keto-reductase
MTLSFSDTYRLNNGIEMPRHGFGVYKLTDEARMRTALETAVDVGYRLFDTASFYHNEKELGDFFASSGLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQIDLYLVHWPKQDTFFDTWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFPNHLLHRYLEELHIVHQAWSPLGRGGVLQEQILIDLAEKHGKSPAQIVLRWHLQNNISIIPKSETPSRIRENAAIYDFELSEADMRQVERLNTGERVSHAPDVMYVRSEI
>NZ_HG813247.1|WP_012951100.1|2777787_2778627_+|Cof-type-HAD-IIB-family-hydrolase
MTTQAIILDIDGTLLNDDKQISPETKKALITAQENGVKLILASGRPTTGMHVYAEQLEMEKHHGLLVSYNGAKVVDCATNEELFNQALTVEEGKAVLEHMKQFEVKVMIDKEDYMYTNDVYDCYVPYRGEEINIIQYESRGGNFKLCEKDDLAAFLDYRLSKILTAGDPAYMQKNYQAMMAPFKDTLNCVFTADFYFEFTAQGIDKAKALDTVLTPMGIHAENIVAFGDGHNDITMVEYAGTGIAMQNAVVELKAAASSVTLSNNEDGIAHVLNSLIPS
>NZ_HG813247.1|WP_012951101.1|2776817_2777669_+|MurR/RpiR-family-transcriptional-regulator
MNILIKIRELTNLTNSEKELANYILVNPKKTLQFKPKELAAAAFVSAATIYRLINKLGLNGIGELKIEIASSLRETNAEKDINYDYPILESDTPYQIMTNLNQIYKGTIDETLNNADPEELVKIGEKLINAKTIDVYAASANLFFAQNFKFQMQEIGVLVNVPEEDYIQSLSAANSDENHIAIVVSYGGRSRTLQRVVKILSENNVDIILITSMQDNPLVEFATHKIYMASAENHYNKVSSFSTRQSLLSIFDTLYSIYFNQNYEKNIQYKTTNYQKMNTELE
>NZ_HG813247.1|WP_009913205.1|2776337_2776712_+|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM
MTKPYGVVIISHSKDVAKGVHDIIKEIAPDVSITHAGGTEDGRIGTSFDAVNEAIESNEADKVYTFYDLGSAKMNIETVEEISEKEIILFNAPILEGAYATAAQVQMDEKPEVIAANLKTIEIK
>NZ_HG813247.1|WP_012951102.1|2775737_2776334_+|dihydroxyacetone-kinase-subunit-L
MTYDKDWALRWLNDFGERVQENKQLLSDLDQAIGDGDHGINMARGLSELKKVFTEKEPADLKDVFKTAGMTMVSKVGGASGPLYGTAFLNMSKAVDADTIDAVGLTKVIEAGLEGIEKRGKSHAGEKTMIDVWEPVVHALHQEDLTDDVVDAALQKTKDLKATKGRASYLGERSIGHLDPGAYSSALLFHAMLQTEVS
>NZ_HG813247.1|WP_003732079.1|2774726_2775716_+|dihydroxyacetone-kinase-subunit-DhaK
MKKILNGTDQVVEQMVEGLVKSHADVVHRVEGTRVIARNDKRPGKVGLVSGGGSGHEPAHAGYVGRGMLSAAVCGDVFTSPTPDQIYEGIKAADQGAGVLLIVKNYTGDVMNFEMAADLADADDIKVEQIVVDDDIAVEDSTFTTGRRGVAGTVLVHKIIGAAAEAGASLDELKALGEKVIASVKTLGVALSPCTVPEVGHPGFELGDDEIELGIGIHGEPGFTREKIMPSASLAKQLYERISNESKLLAGDKVVVLVNGMGATPLMEQYVFANDVHELLKNAGVQVAKTLVGDYMTSLEMAGLSLTILKLEDEKWVDMLKLPVDTIAW
>NZ_HG813247.1|WP_003722065.1|2782977_2783442_-|DUF3284-domain-containing-protein
MNVTQKLYISQKECFDTLVSSAIYDVKNATGKTLQVRKLEGYKYQRTMSNGALATTKIVKVQPNELYQFETSSRVNTHTTTYTIKSTSETTCEVTYNELIETEKALNKMNNIIVGFMFGFFRKKRVKNLLKSIELSVINESKQKQEKLAAKSEQ
>NZ_HG813247.1|WP_003728589.1|2783459_2783642_-|DUF3188-domain-containing-protein
MKIVNALFIISIGLIIIMFSPSYGKDGMASVPLLVTGLAVVLIGCVFIVLKIRKDKKEKN
>NZ_HG813247.1|WP_003728590.1|2783644_2783866_-|hypothetical-protein
MIILNCPMKRDYITELLETHDKDGVTFKKIAEQGMKLTFETNIEDEEKAAKIAKETIKATEIGSVLYFQVSVG
>NZ_HG813247.1|WP_003728591.1|2784000_2785365_-|PTS-sugar-transporter-subunit-IIC
MNGLTAFLEKYFVPVAAKIGSQKHLVALRDAFISTMPITMAGSIAVLLNAFFRDFPTDWGWTGFVEAMQPLIDINGYVYNGTLAIVSIIFAFSLGYNLSKAYEVDRLAGGLVSLAAFVMNLTVTVSLDAVKAAIAASNANFDVATLPKEFAGIYGFFSLSQVNGTGLFTAMIFGFISTIIYAKLMRRNIIIKMPDSVPPAVSKAFAAIIPALVALYVVGIIDWAFFKITNMDVITWISKTIQEPLLSLSQGYGAVLLVTFLVQLLWFFGIHGPNVLAPVLESLWGTAQLQNISAAQDGAKLPFEWVRGSFDAYVWMGGSGGTLVLIIALLMFSKRADARTVAKLSLAPGIFNINEPIMFGLPIVLNTIYLIPFLIAPMVMVTIAYFATTLGIVGPVKIAVVWVMPPLLNSFLATGGDWMAPVISLINMVVAFLIWVPFVITANRVGVPEEEMKA
>NZ_HG813247.1|WP_009931588.1|2785807_2785963_+|hypothetical-protein
MAVKRDMPEESKNSKVVKKEHFSIVFPDDIKEPATVEEKKKQDAEKKTDDN
>NZ_HG813247.1|WP_009925039.1|2786534_2787176_-|hypothetical-protein
MQQLKSKKKWLPALIVAVFVGIIVILAIMFGFFQRQEVFDKYEVAYEIDGKLYEVFPISATDIGVDKKSKDKNLYFRVNSYYNIDYLFRLAYKQYEINEPSTNKYYSGLIDYSVADNAYVTQKDVYITNNESYATYDFFDKNGKKIYTYNPEETSNDDYIVRIKPTILQGYEKSDIGSYDDYLNITALFKDKLGMDVNVRIDEDKEMVIFSIK
>NZ_HG813247.1|WP_003732087.1|2787873_2789388_-|gluconokinase
MTSKPYIMGVDIGTSSTKAVLFNQRGEVIFRQATHYELITDETGKAEESPTEIFDAVLTSIQAVMKNINTEELAGISFSSAMHSLIMVGSNGELLTECITWADGRSSETLEKVKRDNYLFQLYEATGTPIHPMSPFAKICWLKEEKPTLFKRTEKFVDIKSYILYRLFGVWVMDESLASGTGLYNIMEHDWEFEAMEIVKLTPDFLPKVVPETYQLAGVKKEYAELMGIPENLPFIIGGSDGALANIGIQATGQNDVTITVGTSGAVRKLTDQFQIDSRGRTFCYGAGDGYFIAGGAVNNGGKVVEWGLQQFGSEAEISRRDFASFIAKIEEVPPGAAGLLFQPYLLGERAPFWTNDIRGGFVGLTINHTKAHFIRAILEGVAFNLAEVYEAVSAPDDIIYVTGGISAHDAWCKLLADILNREIRVPHTIEGSSLGAAIIGMRSLGILKDLNLKHTLPIKAVYHPSENVLKYAELRLIFKQVTTQLMSSYSQLNSWQKKFDINS
>NZ_HG813247.1|WP_003722073.1|2789503_2790442_-|GW-domain-containing-glycosaminoglycan-binding-protein
MKKLLSGLIVVLMVSLLGHSFNAEAASYEKIIYDKAVNLKGVVNQSKRNDGINSKMYKTSSSVKYLGSAKKYDKKTLIITREGKTARAKWYYCKLGNTTIGWIDSRAFTNIGKPTIADTVPALWNSKKAIITTKPKSTTATTYFFQKNSAGNWYEVRHFTSHIGKWGFDPKFSEKSSGTPVGVYRTGIAFGQKGNPGTKLTFRAITNRSYWISNSNDKAYNTWQERNSSSSADEKMKIPQYKYGMEVKYNAKRVKGKGSAVFYHVDSPKYNYTLGCVAQSEANTKEVLKFADKNTLIVLGEESRIKTFYGIN
>NZ_HG813247.1|WP_003722074.1|2790484_2791432_-|LPXTG-cell-wall-anchor-domain-containing-protein
MKKFHGLILTALVTCLIIPFSLAASAETNENGNNSTPTEEKTTDTTENIITEEKTEPAEPTKDTTVTPPQKSKVQTTIDITDSQEVYSYEQNSKIDLKDFTATLTDYTDTKLTNYRLAANSKLSTAQTGIQEVTLLGDNEDGKTTAVKLNYLVKEKTAQLTITDMNFDLETKIFTGKTKPFASVYMSSPADENFGEGTTTADKDGYFYAEWATTPKQITAYAFDESGNYSEEVTYQVPAKKQNEAVVTAPDKVKKIETKNAVKSATTKPTDVTKVTKDDKTDLPSTGDKGTEWIFVVAGVIVILVAVLLLRKRKK
>NZ_HG813247.1|WP_003732089.1|2791572_2793312_-|thiol-reductant-ABC-exporter-subunit-CydC
MRKSSWIIPYIKENRGLFLLVIFLGTLTFASAGALMFTSGHLISKSSLMPESIMAVYISTVGVRAFGIMRSVSRYVERLSSHSLVLRILEKMRVRLYRLLEPQALLLKSRYKTGDILGLLAGDIEHLQNFYLTTMLPAIVSLVLYAGVVIALGAFSIPFAALFVLLIGLLVLVLPWVSLLYARGKNAYLKQGRNSLYQKFTDAVFGISDWKFSGREKTFISNYEKDEADMLRTENKQFHFVNWRDFFSQLVVGFMVIVMVYWSTAESRDGAFSGTMIAAFVLAIMALAEAFVPVSSAISDKSLYQDSLARLDKIEDPALPTFEEETKEIERINTENVVLKAENLTFAYDEKSPEILNGFDFTLQQGEKVAIIGRSGTGKSTFLKLVQGALLPTAGKVTMNDVEVEKLRPQIPELTSMLNQKAHLFSTTVLNNIRLGNQDASDEEVYEAAKKVQLHDFIMSMPDGYHTQMSEMGERFSGGERGRIALARILLQNTPIVILDEPTVGLDPITERDLLATIFETLADKSLIWVTHHLVGAEKMDRVLFLEEGKTLMEGPHAELMAEEPRYKRLYQLDRPIEL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_HG813247_2	2.1\|515197\|35\|NZ_HG813247\|PILER-CR,CRT	515197-515231	35	NZ_HG813247.1	1259518-1259552	0	1.0
NZ_HG813247_2	2.6\|515517\|36\|NZ_HG813247\|PILER-CR,CRT	515517-515552	36	NZ_HG813247.1	1258370-1258405	0	1.0

1. spacer 2.1|515197|35|NZ_HG813247|PILER-CR,CRT matches to position: 1259518-1259552, mismatch: 0, identity: 1.0

acagatcaaactccggaagggtgattgtaaatggc	CRISPR spacer
acagatcaaactccggaagggtgattgtaaatggc	Protospacer
***********************************

2. spacer 2.6|515517|36|NZ_HG813247|PILER-CR,CRT matches to position: 1258370-1258405, mismatch: 0, identity: 1.0

aaaataggaggaaataaattatgactatcaaattaa	CRISPR spacer
aaaataggaggaaataaattatgactatcaaattaa	Protospacer
************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_HG813247_2	2.1\|515197\|35\|NZ_HG813247\|PILER-CR,CRT	515197-515231	35	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	214611-214645	0	1.0
NZ_HG813247_2	2.1\|515197\|35\|NZ_HG813247\|PILER-CR,CRT	515197-515231	35	MT500540	Listeria phage LP-HM00113468, complete genome	39834-39868	0	1.0
NZ_HG813247_2	2.1\|515197\|35\|NZ_HG813247\|PILER-CR,CRT	515197-515231	35	KJ094023	Listeria phage LP-101, complete genome	5084-5118	0	1.0
NZ_HG813247_2	2.6\|515517\|36\|NZ_HG813247\|PILER-CR,CRT	515517-515552	36	MT500540	Listeria phage LP-HM00113468, complete genome	683-718	0	1.0
NZ_HG813247_2	2.6\|515517\|36\|NZ_HG813247\|PILER-CR,CRT	515517-515552	36	NC_009812	Listeria phage B025, complete genome	3896-3931	0	1.0
NZ_HG813247_2	2.6\|515517\|36\|NZ_HG813247\|PILER-CR,CRT	515517-515552	36	KJ094023	Listeria phage LP-101, complete genome	3936-3971	0	1.0
NZ_HG813247_2	2.7\|515582\|35\|NZ_HG813247\|PILER-CR,CRT	515582-515616	35	DQ003642	Listeria phage A006, complete genome	15712-15746	0	1.0
NZ_HG813247_2	2.3\|515326\|35\|NZ_HG813247\|PILER-CR,CRT	515326-515360	35	MH341453	Listeria phage PSU-VKH-LP041, complete genome	10139-10173	1	0.971
NZ_HG813247_2	2.5\|515453\|35\|NZ_HG813247\|PILER-CR,CRT	515453-515487	35	NC_021539	Listeria phage LP-030-2, complete genome	18926-18960	1	0.971
NZ_HG813247_2	2.5\|515453\|35\|NZ_HG813247\|PILER-CR,CRT	515453-515487	35	KJ094023	Listeria phage LP-101, complete genome	22882-22916	1	0.971
NZ_HG813247_2	2.6\|515517\|36\|NZ_HG813247\|PILER-CR,CRT	515517-515552	36	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	213463-213498	1	0.972
NZ_HG813247_2	2.8\|515197\|36\|NZ_HG813247\|CRISPRCasFinder	515197-515232	36	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	214611-214646	1	0.972
NZ_HG813247_2	2.8\|515197\|36\|NZ_HG813247\|CRISPRCasFinder	515197-515232	36	MT500540	Listeria phage LP-HM00113468, complete genome	39833-39868	1	0.972
NZ_HG813247_2	2.8\|515197\|36\|NZ_HG813247\|CRISPRCasFinder	515197-515232	36	KJ094023	Listeria phage LP-101, complete genome	5084-5119	1	0.972
NZ_HG813247_2	2.10\|515326\|36\|NZ_HG813247\|CRISPRCasFinder	515326-515361	36	MH341453	Listeria phage PSU-VKH-LP041, complete genome	10139-10174	1	0.972
NZ_HG813247_2	2.12\|515453\|36\|NZ_HG813247\|CRISPRCasFinder	515453-515488	36	NC_021539	Listeria phage LP-030-2, complete genome	18926-18961	1	0.972
NZ_HG813247_2	2.12\|515453\|36\|NZ_HG813247\|CRISPRCasFinder	515453-515488	36	KJ094023	Listeria phage LP-101, complete genome	22882-22917	1	0.972
NZ_HG813247_2	2.13\|515517\|37\|NZ_HG813247\|CRISPRCasFinder	515517-515553	37	NC_009812	Listeria phage B025, complete genome	3896-3932	1	0.973
NZ_HG813247_2	2.13\|515517\|37\|NZ_HG813247\|CRISPRCasFinder	515517-515553	37	KJ094023	Listeria phage LP-101, complete genome	3936-3972	1	0.973
NZ_HG813247_2	2.13\|515517\|37\|NZ_HG813247\|CRISPRCasFinder	515517-515553	37	MT500540	Listeria phage LP-HM00113468, complete genome	682-718	1	0.973
NZ_HG813247_2	2.14\|515582\|36\|NZ_HG813247\|CRISPRCasFinder	515582-515617	36	DQ003642	Listeria phage A006, complete genome	15711-15746	1	0.972
NZ_HG813247_2	2.1\|515197\|35\|NZ_HG813247\|PILER-CR,CRT	515197-515231	35	NC_009812	Listeria phage B025, complete genome	5044-5078	2	0.943
NZ_HG813247_2	2.3\|515326\|35\|NZ_HG813247\|PILER-CR,CRT	515326-515360	35	NC_009813	Listeria phage B054, complete genome	10139-10173	2	0.943
NZ_HG813247_2	2.5\|515453\|35\|NZ_HG813247\|PILER-CR,CRT	515453-515487	35	NC_009812	Listeria phage B025, complete genome	23381-23415	2	0.943
NZ_HG813247_2	2.10\|515326\|36\|NZ_HG813247\|CRISPRCasFinder	515326-515361	36	NC_009813	Listeria phage B054, complete genome	10139-10174	2	0.944
NZ_HG813247_2	2.12\|515453\|36\|NZ_HG813247\|CRISPRCasFinder	515453-515488	36	NC_009812	Listeria phage B025, complete genome	23381-23416	2	0.944
NZ_HG813247_2	2.13\|515517\|37\|NZ_HG813247\|CRISPRCasFinder	515517-515553	37	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	213463-213499	2	0.946
NZ_HG813247_2	2.8\|515197\|36\|NZ_HG813247\|CRISPRCasFinder	515197-515232	36	NC_009812	Listeria phage B025, complete genome	5044-5079	3	0.917
NZ_HG813247_2	2.6\|515517\|36\|NZ_HG813247\|PILER-CR,CRT	515517-515552	36	JN700520	Staphylococcus phage StB12, complete genome	6832-6867	5	0.861
NZ_HG813247_2	2.13\|515517\|37\|NZ_HG813247\|CRISPRCasFinder	515517-515553	37	JN700520	Staphylococcus phage StB12, complete genome	6832-6868	6	0.838
NZ_HG813247_2	2.6\|515517\|36\|NZ_HG813247\|PILER-CR,CRT	515517-515552	36	MW084976	Bacillus phage Kirov, complete genome	27565-27600	8	0.778
NZ_HG813247_2	2.13\|515517\|37\|NZ_HG813247\|CRISPRCasFinder	515517-515553	37	MW084976	Bacillus phage Kirov, complete genome	27565-27601	9	0.757
NZ_HG813247_2	2.7\|515582\|35\|NZ_HG813247\|PILER-CR,CRT	515582-515616	35	NZ_CP029455	Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence	130632-130666	11	0.686
NZ_HG813247_2	2.7\|515582\|35\|NZ_HG813247\|PILER-CR,CRT	515582-515616	35	NZ_CP015592	Bacillus cereus strain AR156 plasmid pAR460, complete sequence	17622-17656	11	0.686
NZ_HG813247_2	2.7\|515582\|35\|NZ_HG813247\|PILER-CR,CRT	515582-515616	35	NZ_CP009368	Bacillus cereus strain FM1 plasmid unnamed, complete sequence	31860-31894	11	0.686
NZ_HG813247_2	2.7\|515582\|35\|NZ_HG813247\|PILER-CR,CRT	515582-515616	35	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	338888-338922	11	0.686

1. spacer 2.1|515197|35|NZ_HG813247|PILER-CR,CRT matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 0, identity: 1.0

acagatcaaactccggaagggtgattgtaaatggc	CRISPR spacer
acagatcaaactccggaagggtgattgtaaatggc	Protospacer
***********************************

2. spacer 2.1|515197|35|NZ_HG813247|PILER-CR,CRT matches to MT500540 (Listeria phage LP-HM00113468, complete genome) position: , mismatch: 0, identity: 1.0

acagatcaaactccggaagggtgattgtaaatggc	CRISPR spacer
acagatcaaactccggaagggtgattgtaaatggc	Protospacer
***********************************

3. spacer 2.1|515197|35|NZ_HG813247|PILER-CR,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 0, identity: 1.0

acagatcaaactccggaagggtgattgtaaatggc	CRISPR spacer
acagatcaaactccggaagggtgattgtaaatggc	Protospacer
***********************************

4. spacer 2.6|515517|36|NZ_HG813247|PILER-CR,CRT matches to MT500540 (Listeria phage LP-HM00113468, complete genome) position: , mismatch: 0, identity: 1.0

aaaataggaggaaataaattatgactatcaaattaa	CRISPR spacer
aaaataggaggaaataaattatgactatcaaattaa	Protospacer
************************************

5. spacer 2.6|515517|36|NZ_HG813247|PILER-CR,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 0, identity: 1.0

aaaataggaggaaataaattatgactatcaaattaa	CRISPR spacer
aaaataggaggaaataaattatgactatcaaattaa	Protospacer
************************************

6. spacer 2.6|515517|36|NZ_HG813247|PILER-CR,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 0, identity: 1.0

aaaataggaggaaataaattatgactatcaaattaa	CRISPR spacer
aaaataggaggaaataaattatgactatcaaattaa	Protospacer
************************************

7. spacer 2.7|515582|35|NZ_HG813247|PILER-CR,CRT matches to DQ003642 (Listeria phage A006, complete genome) position: , mismatch: 0, identity: 1.0

tttgttgaatcaacggatatagattttacaatttc	CRISPR spacer
tttgttgaatcaacggatatagattttacaatttc	Protospacer
***********************************

8. spacer 2.3|515326|35|NZ_HG813247|PILER-CR,CRT matches to MH341453 (Listeria phage PSU-VKH-LP041, complete genome) position: , mismatch: 1, identity: 0.971

gcgatttttgtcaaagggacagcgatgggttacaa	CRISPR spacer
gcgatttttgtcaaaggaacagcgatgggttacaa	Protospacer
*****************.*****************

9. spacer 2.5|515453|35|NZ_HG813247|PILER-CR,CRT matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.971

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctat	Protospacer
******************* ***************

10. spacer 2.5|515453|35|NZ_HG813247|PILER-CR,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.971

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctat	Protospacer
******************* ***************

11. spacer 2.6|515517|36|NZ_HG813247|PILER-CR,CRT matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 1, identity: 0.972

aaaataggaggaaataaattatgactatcaaattaa	CRISPR spacer
aaaataggaggaaatagattatgactatcaaattaa	Protospacer
****************.*******************

12. spacer 2.8|515197|36|NZ_HG813247|CRISPRCasFinder matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 1, identity: 0.972

acagatcaaactccggaagggtgattgtaaatggcg	CRISPR spacer
acagatcaaactccggaagggtgattgtaaatggct	Protospacer
***********************************

13. spacer 2.8|515197|36|NZ_HG813247|CRISPRCasFinder matches to MT500540 (Listeria phage LP-HM00113468, complete genome) position: , mismatch: 1, identity: 0.972

acagatcaaactccggaagggtgattgtaaatggcg	CRISPR spacer
acagatcaaactccggaagggtgattgtaaatggct	Protospacer
***********************************

14. spacer 2.8|515197|36|NZ_HG813247|CRISPRCasFinder matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.972

acagatcaaactccggaagggtgattgtaaatggcg	CRISPR spacer
acagatcaaactccggaagggtgattgtaaatggct	Protospacer
***********************************

15. spacer 2.10|515326|36|NZ_HG813247|CRISPRCasFinder matches to MH341453 (Listeria phage PSU-VKH-LP041, complete genome) position: , mismatch: 1, identity: 0.972

gcgatttttgtcaaagggacagcgatgggttacaag	CRISPR spacer
gcgatttttgtcaaaggaacagcgatgggttacaag	Protospacer
*****************.******************

16. spacer 2.12|515453|36|NZ_HG813247|CRISPRCasFinder matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.972

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctata	Protospacer
******************* ****************

17. spacer 2.12|515453|36|NZ_HG813247|CRISPRCasFinder matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.972

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctata	Protospacer
******************* ****************

18. spacer 2.13|515517|37|NZ_HG813247|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 1, identity: 0.973

aaaataggaggaaataaattatgactatcaaattaag	CRISPR spacer
aaaataggaggaaataaattatgactatcaaattaaa	Protospacer
************************************.

19. spacer 2.13|515517|37|NZ_HG813247|CRISPRCasFinder matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.973

aaaataggaggaaataaattatgactatcaaattaag	CRISPR spacer
aaaataggaggaaataaattatgactatcaaattaaa	Protospacer
************************************.

20. spacer 2.13|515517|37|NZ_HG813247|CRISPRCasFinder matches to MT500540 (Listeria phage LP-HM00113468, complete genome) position: , mismatch: 1, identity: 0.973

aaaataggaggaaataaattatgactatcaaattaag	CRISPR spacer
aaaataggaggaaataaattatgactatcaaattaaa	Protospacer
************************************.

21. spacer 2.14|515582|36|NZ_HG813247|CRISPRCasFinder matches to DQ003642 (Listeria phage A006, complete genome) position: , mismatch: 1, identity: 0.972

tttgttgaatcaacggatatagattttacaatttcg	CRISPR spacer
tttgttgaatcaacggatatagattttacaatttct	Protospacer
***********************************

22. spacer 2.1|515197|35|NZ_HG813247|PILER-CR,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.943

acagatcaaactccggaagggtgattgtaaatggc	CRISPR spacer
gcagaacaaactccggaagggtgattgtaaatggc	Protospacer
.**** *****************************

23. spacer 2.3|515326|35|NZ_HG813247|PILER-CR,CRT matches to NC_009813 (Listeria phage B054, complete genome) position: , mismatch: 2, identity: 0.943

gcgatttttgtcaaagggacagcgatgggttacaa	CRISPR spacer
gcgatttttgtcaaaggaacggcgatgggttacaa	Protospacer
*****************.**.**************

24. spacer 2.5|515453|35|NZ_HG813247|PILER-CR,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.943

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactatctcaactcctttctat	Protospacer
*****************.* ***************

25. spacer 2.10|515326|36|NZ_HG813247|CRISPRCasFinder matches to NC_009813 (Listeria phage B054, complete genome) position: , mismatch: 2, identity: 0.944

gcgatttttgtcaaagggacagcgatgggttacaag	CRISPR spacer
gcgatttttgtcaaaggaacggcgatgggttacaag	Protospacer
*****************.**.***************

26. spacer 2.12|515453|36|NZ_HG813247|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.944

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactatctcaactcctttctata	Protospacer
*****************.* ****************

27. spacer 2.13|515517|37|NZ_HG813247|CRISPRCasFinder matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 2, identity: 0.946

aaaataggaggaaataaattatgactatcaaattaag	CRISPR spacer
aaaataggaggaaatagattatgactatcaaattaaa	Protospacer
****************.*******************.

28. spacer 2.8|515197|36|NZ_HG813247|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 3, identity: 0.917

acagatcaaactccggaagggtgattgtaaatggcg	CRISPR spacer
gcagaacaaactccggaagggtgattgtaaatggct	Protospacer
.**** *****************************

29. spacer 2.6|515517|36|NZ_HG813247|PILER-CR,CRT matches to JN700520 (Staphylococcus phage StB12, complete genome) position: , mismatch: 5, identity: 0.861

aaaataggaggaaataaattatgact-atcaaattaa	CRISPR spacer
taaataggaggaagtaaataatgactaatcaaacta-	Protospacer
 ************.***** ****** ******.**

30. spacer 2.13|515517|37|NZ_HG813247|CRISPRCasFinder matches to JN700520 (Staphylococcus phage StB12, complete genome) position: , mismatch: 6, identity: 0.838

aaaataggaggaaataaattatgact-atcaaattaag	CRISPR spacer
taaataggaggaagtaaataatgactaatcaaactat-	Protospacer
 ************.***** ****** ******.**

31. spacer 2.6|515517|36|NZ_HG813247|PILER-CR,CRT matches to MW084976 (Bacillus phage Kirov, complete genome) position: , mismatch: 8, identity: 0.778

aaaataggaggaaataaattatgactatcaaattaa	CRISPR spacer
ttaataggaggaaataaataatggctatcgtaagaa	Protospacer
  ***************** ***.*****. *  **

32. spacer 2.13|515517|37|NZ_HG813247|CRISPRCasFinder matches to MW084976 (Bacillus phage Kirov, complete genome) position: , mismatch: 9, identity: 0.757

aaaataggaggaaataaattatgactatcaaattaag	CRISPR spacer
ttaataggaggaaataaataatggctatcgtaagaaa	Protospacer
  ***************** ***.*****. *  **.

33. spacer 2.7|515582|35|NZ_HG813247|PILER-CR,CRT matches to NZ_CP029455 (Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence) position: , mismatch: 11, identity: 0.686

tttgttgaatcaacggatatagattttacaatttc	CRISPR spacer
agaaaaaaatcaaccgatatagattttaaaatctt	Protospacer
   .  .******* ************* ***.*.

34. spacer 2.7|515582|35|NZ_HG813247|PILER-CR,CRT matches to NZ_CP015592 (Bacillus cereus strain AR156 plasmid pAR460, complete sequence) position: , mismatch: 11, identity: 0.686

tttgttgaatcaacggatatagattttacaatttc	CRISPR spacer
aagaaaaaatcaaccgatatagattttaaaatctt	Protospacer
   .  .******* ************* ***.*.

35. spacer 2.7|515582|35|NZ_HG813247|PILER-CR,CRT matches to NZ_CP009368 (Bacillus cereus strain FM1 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

tttgttgaatcaacggatatagattttacaatttc	CRISPR spacer
agaaaaaaatcaaccgatatagattttaaaatctt	Protospacer
   .  .******* ************* ***.*.

36. spacer 2.7|515582|35|NZ_HG813247|PILER-CR,CRT matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.686

tttgttgaatcaacggatatagattttacaatttc	CRISPR spacer
agaaaaaaatcaaccgatatagattttaaaatctt	Protospacer
   .  .******* ************* ***.*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

123724 : 130249

Listeria_phage(33.33%)

tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003721739.1\|123724_124177_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9
WP_003721740.1\|124182_124518_-	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_003732219.1\|124734_125163_+	hypothetical protein	NA	NA	NA	NA
WP_003732220.1\|125174_125591_+	hypothetical protein	A8ASQ1	Listeria_phage	1.3e-20	39.3
WP_012952083.1\|125868_126258_+	DUF5072 family protein	NA	NA	NA	NA
WP_003721744.1\|126270_126783_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_003721745.1\|126830_127133_+	hypothetical protein	NA	NA	NA	NA
WP_012952082.1\|127174_127579_+	hypothetical protein	NA	NA	NA	NA
WP_012952081.1\|127565_129434_+	membrane protein	A0A097PAU2	Streptococcus_pyogenes_phage	3.5e-20	45.8
WP_003734720.1\|129430_130249_+\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	7.2e-39	35.0

DBSCAN-SWA_2

1102442 : 1111995

Hokovirus(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003721506.1\|1102442_1102826_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7
WP_003732709.1\|1102847_1103831_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	4.1e-12	34.6
WP_010989660.1\|1103845_1104859_+	glycosyltransferase	A0A1V0SAH6	Catovirus	7.9e-11	32.0
WP_003721509.1\|1105067_1106558_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.5e-114	49.7
WP_003727000.1\|1106569_1107394_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	9.7e-68	52.6
WP_012951453.1\|1107406_1107715_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_003730540.1\|1107774_1108179_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_012951454.1\|1108307_1109864_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	3.0e-17	28.1
WP_012951455.1\|1110081_1111995_+	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	1.3e-59	36.9

DBSCAN-SWA_3

1207651 : 1313203

114

Listeria_phage(74.19%)

terminase,holin,portal,tRNA,integrase,capsid,protease,tail

attL 1233476:1233494|attR 1275445:1275463

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003736387.1\|1207651_1208704_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.3e-29	34.9
WP_012951511.1\|1208703_1211112_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003721621.1\|1211272_1211974_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.0e-33	35.8
WP_012951512.1\|1211987_1215398_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_003721623.1\|1215495_1215948_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003721624.1\|1215963_1219164_+	MMPL family transporter	NA	NA	NA	NA
WP_003732773.1\|1219270_1219945_+	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	7.5e-50	47.7
WP_072215733.1\|1219982_1220909_-	ribonuclease HIII	NA	NA	NA	NA
WP_003740576.1\|1221062_1221326_+	cell division protein ZapA	NA	NA	NA	NA
WP_012951513.1\|1221325_1221868_+	CvpA family protein	NA	NA	NA	NA
WP_003723851.1\|1221960_1223673_+	DNA polymerase/3'-5' exonuclease PolX	A0A2H4UV14	Bodo_saltans_virus	5.1e-18	24.8
WP_010989713.1\|1223695_1226053_+	endonuclease MutS2	Q94M10	Lactobacillus_phage	1.0e-21	50.4
WP_003723853.1\|1226133_1226445_+	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	5.4e-19	39.6
WP_003733800.1\|1226520_1228332_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_003732778.1\|1228520_1229735_+	aspartate kinase	NA	NA	NA	NA
WP_003733801.1\|1229790_1230285_-	YslB family protein	NA	NA	NA	NA
WP_003723856.1\|1230432_1231233_+	glutamate racemase	NA	NA	NA	NA
WP_003726032.1\|1231245_1231992_+	ribonuclease PH	NA	NA	NA	NA
WP_012951514.1\|1231995_1232607_+	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_012951515.1\|1232643_1233168_+	metallophosphoesterase	NA	NA	NA	NA
WP_025370561.1\|1233453_1234608_-\|integrase	site-specific integrase	A0A059T688	Listeria_phage	9.7e-215	98.2
1233476:1233494	attL	NA	NA	NA	NA
WP_025370562.1\|1234753_1235410_-	DUF4352 domain-containing protein	NA	NA	NA	NA
WP_025370563.1\|1235461_1235914_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	1.7e-82	96.7
WP_025370564.1\|1235930_1236254_-	helix-turn-helix transcriptional regulator	A0A059T6G1	Listeria_phage	5.5e-35	71.0
WP_025370565.1\|1236712_1237030_-	hypothetical protein	NA	NA	NA	NA
WP_025370566.1\|1237095_1237419_+	hypothetical protein	NA	NA	NA	NA
WP_003730994.1\|1237566_1237770_-	hypothetical protein	NA	NA	NA	NA
WP_009929536.1\|1237836_1238040_+	helix-turn-helix transcriptional regulator	A0A059T5F8	Listeria_phage	3.1e-28	100.0
WP_015987310.1\|1238041_1238284_+	hypothetical protein	A8ATD2	Listeria_phage	1.4e-43	100.0
WP_023548967.1\|1238286_1238472_+	hypothetical protein	A0A059T7Z3	Listeria_phage	4.4e-29	98.4
WP_009929542.1\|1238706_1238859_+	hypothetical protein	A8ATD4	Listeria_phage	1.5e-19	100.0
WP_009929543.1\|1238995_1239709_+	SAM-dependent DNA methyltransferase	A8ATD5	Listeria_phage	2.4e-131	98.7
WP_025370567.1\|1239719_1240664_+\|integrase	site-specific integrase	A8ATD6	Listeria_phage	1.0e-174	97.1
WP_025370568.1\|1240676_1241363_+	hypothetical protein	A8ATD7	Listeria_phage	4.1e-112	88.4
WP_025370570.1\|1241906_1242497_+	pentapeptide repeat-containing protein	A0A060AFJ6	Listeria_phage	2.6e-38	73.5
WP_003731704.1\|1242604_1242934_+	hypothetical protein	A8ATE1	Listeria_phage	1.1e-57	100.0
WP_025370571.1\|1242930_1243206_+	hypothetical protein	A0A059T7Z9	Listeria_phage	2.9e-45	95.6
WP_025370574.1\|1244312_1244696_+	hypothetical protein	Q8W5W2	Listeria_phage	1.3e-62	95.3
WP_025370575.1\|1244697_1245177_+	siphovirus Gp157 family protein	Q8W5W1	Listeria_phage	1.3e-77	98.7
WP_025370576.1\|1245189_1245879_+	AAA family ATPase	A0A059T7T3	Listeria_phage	2.2e-129	99.6
WP_025370577.1\|1245942_1247199_+	DEAD/DEAH box helicase	Q8W5V9	Listeria_phage	3.6e-231	95.2
WP_025370578.1\|1247223_1247709_+	DUF669 domain-containing protein	A0A059T5G4	Listeria_phage	1.9e-87	99.4
WP_025370579.1\|1247731_1250005_+	DNA primase	R4IBW2	Listeria_phage	0.0e+00	98.3
WP_012951539.1\|1250719_1251037_+	VRR-NUC domain-containing protein	A8ATF4	Listeria_phage	7.3e-48	89.3
WP_020830767.1\|1251038_1251251_+	hypothetical protein	NA	NA	NA	NA
WP_025370580.1\|1251760_1252300_+	DUF3310 domain-containing protein	A8ATF5	Listeria_phage	1.6e-71	74.3
WP_003731656.1\|1252594_1252750_+	hypothetical protein	NA	NA	NA	NA
WP_003731655.1\|1252810_1253038_+	hypothetical protein	NA	NA	NA	NA
WP_003731654.1\|1253050_1253476_+	DUF722 domain-containing protein	A0A059T6H4	Listeria_phage	1.8e-73	99.3
WP_003731652.1\|1254067_1254382_+	HNH endonuclease	A8ATF8	Listeria_phage	3.2e-56	98.1
WP_025370582.1\|1254430_1254787_+\|terminase	P27 family phage terminase small subunit	A0A059T7Y1	Listeria_phage	4.5e-46	97.0
WP_025370583.1\|1254783_1256427_+\|terminase	terminase large subunit	A0A059T7Q8	Listeria_phage	0.0e+00	98.5
WP_025370584.1\|1256438_1257569_+\|portal	phage portal protein	A0A059T6F0	Listeria_phage	9.5e-215	99.5
WP_025370585.1\|1257565_1258363_+\|protease	Clp protease ClpP	A0A059T5F2	Listeria_phage	1.1e-143	99.6
WP_014930913.1\|1258389_1259541_+\|capsid	phage major capsid protein	A0A059T678	Listeria_phage	6.3e-214	100.0
WP_162859696.1\|1259547_1259718_+	hypothetical protein	A0A059T7Y2	Listeria_phage	6.9e-21	96.4
WP_025370586.1\|1259727_1260027_+	hypothetical protein	A0A059T7R0	Listeria_phage	2.6e-47	99.0
WP_025370587.1\|1260010_1260376_+	hypothetical protein	A0A059T6F2	Listeria_phage	2.4e-63	99.2
WP_025370588.1\|1260372_1260774_+	hypothetical protein	A8ATA2	Listeria_phage	2.2e-65	95.5
WP_025370589.1\|1260770_1261154_+	hypothetical protein	A0A059T681	Listeria_phage	1.9e-66	98.4
WP_025370590.1\|1261174_1261762_+\|tail	phage tail protein	A0A059T7Y4	Listeria_phage	1.3e-106	99.0
WP_025370591.1\|1261832_1262165_+	hypothetical protein	A0A059T7R2	Listeria_phage	8.7e-52	97.3
WP_009931626.1\|1262215_1262377_+	hypothetical protein	A0A059T6F4	Listeria_phage	4.3e-20	98.0
WP_025370592.1\|1262380_1267300_+\|tail	phage tail tape measure protein	A0A059T5F4	Listeria_phage	0.0e+00	93.9
WP_025370593.1\|1267292_1268942_+\|tail	phage tail family protein	A0A059T682	Listeria_phage	0.0e+00	99.5
WP_025370594.1\|1268954_1271249_+\|tail	phage tail protein	A0A059T7Y6	Listeria_phage	0.0e+00	98.7
WP_025370595.1\|1271238_1272330_+	hypothetical protein	A0A059T7R4	Listeria_phage	1.1e-188	91.8
WP_003733957.1\|1272380_1272686_+	hypothetical protein	A0A059T5E6	Listeria_phage	1.8e-43	100.0
WP_003723294.1\|1272685_1272967_+\|holin	phage holin	A8ATW3	Listeria_phage	3.0e-45	100.0
WP_025370596.1\|1272966_1273674_+	M15 family metallopeptidase	A8ATW4	Listeria_phage	1.0e-129	97.9
WP_025370597.1\|1273821_1274523_+	DUF3800 domain-containing protein	R4IBV1	Listeria_phage	6.4e-129	97.8
WP_014930932.1\|1275001_1275235_+	hypothetical protein	A8ATX0	Listeria_phage	2.3e-35	94.8
WP_031672409.1\|1275231_1275423_+	hypothetical protein	A8ATC6	Listeria_phage	1.7e-28	98.4
WP_012951565.1\|1275882_1277241_+	DUF1254 domain-containing protein	NA	NA	NA	NA
1275445:1275463	attR	NA	NA	NA	NA
WP_012951566.1\|1277281_1277875_-	DUF1801 domain-containing protein	NA	NA	NA	NA
WP_009914084.1\|1278028_1278436_-	glyoxalase/bleomycin resistance/extradiol dioxygenase family protein	NA	NA	NA	NA
WP_009924169.1\|1278600_1279200_+	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	5.8e-30	41.0
WP_003723543.1\|1279231_1279492_-	hypothetical protein	NA	NA	NA	NA
WP_010989717.1\|1279615_1281028_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	8.3e-51	31.8
WP_003723545.1\|1281052_1281316_+	DUF3116 family protein	NA	NA	NA	NA
WP_003723546.1\|1281483_1281960_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_012951567.1\|1281997_1282243_-	hypothetical protein	NA	NA	NA	NA
WP_012951568.1\|1282239_1283445_-	MFS transporter	NA	NA	NA	NA
WP_003723549.1\|1283649_1284309_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_003723550.1\|1284350_1284545_-	hypothetical protein	NA	NA	NA	NA
WP_003723551.1\|1284611_1285460_-	YitT family protein	NA	NA	NA	NA
WP_003723553.1\|1285791_1285929_-	hypothetical protein	NA	NA	NA	NA
WP_009931701.1\|1286079_1286793_+	trehalose operon repressor	NA	NA	NA	NA
WP_012951570.1\|1286823_1288470_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_003723556.1\|1288488_1289973_-	PTS system trehalose-specific EIIBC component	NA	NA	NA	NA
WP_003723557.1\|1290088_1290541_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_012951571.1\|1290587_1291052_-	hypothetical protein	NA	NA	NA	NA
WP_003723559.1\|1291240_1292161_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_003723560.1\|1292180_1293428_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.2e-106	51.8
WP_003723561.1\|1293411_1294242_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.3e-47	42.4
WP_003723562.1\|1294377_1295517_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_003723563.1\|1295597_1295993_-	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003727524.1\|1296143_1296359_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010989719.1\|1296477_1297011_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003732795.1\|1297028_1297694_+	hypothetical protein	NA	NA	NA	NA
WP_003732796.1\|1297955_1298894_+	hypothetical protein	NA	NA	NA	NA
WP_003723884.1\|1299008_1300292_+	trigger factor	NA	NA	NA	NA
WP_003723886.1\|1300476_1301736_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_003723887.1\|1301854_1302421_+	type I signal peptidase SipX	NA	NA	NA	NA
WP_009924619.1\|1302455_1303025_+	type I signal peptidase SipY	NA	NA	NA	NA
WP_003723889.1\|1303126_1303669_+	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003723890.1\|1303678_1304542_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003723891.1\|1304538_1305324_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	3.0e-26	39.2
WP_003723892.1\|1305457_1306318_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_012951572.1\|1306589_1308668_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	3.2e-107	37.5
WP_009924616.1\|1308730_1310035_+\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_009911635.1\|1310317_1311220_+	tyrosine recombinase XerC	A0A097EYL9	Mycobacterium_phage	1.2e-13	28.6
WP_003724001.1\|1311240_1311780_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_003732800.1\|1311793_1313203_+\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	3.7e-43	28.7

DBSCAN-SWA_4

1846308 : 1854594

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722243.1\|1846308_1846875_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.0e-25	35.9
WP_012951771.1\|1846871_1847921_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	4.6e-62	43.5
WP_003722245.1\|1847939_1849367_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_025370613.1\|1849351_1851571_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.7e-159	41.1
WP_003722247.1\|1851563_1852247_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003722248.1\|1852250_1852496_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_012951773.1\|1852507_1853221_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	1.2e-42	38.3
WP_003729814.1\|1853301_1854594_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

DBSCAN-SWA_5

2367185 : 2406981

Listeria_phage(92.98%)

terminase,holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025370627.1\|2367185_2367617_+	hypothetical protein	A8ATJ2	Listeria_phage	4.1e-25	81.7
WP_003733518.1\|2367613_2368114_+	AP2 domain-containing protein	A8ATW6	Listeria_phage	1.4e-64	71.8
WP_012951560.1\|2368319_2369318_-	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	3.9e-71	44.8
WP_025370628.1\|2369420_2370266_-	M15 family metallopeptidase	A0A059T7Y8	Listeria_phage	4.7e-134	91.2
WP_012951558.1\|2370265_2370523_-\|holin	phage holin	A8ATB7	Listeria_phage	3.2e-25	69.0
WP_014930187.1\|2370522_2370825_-	hypothetical protein	A0A059T5E6	Listeria_phage	2.2e-38	92.0
WP_025370629.1\|2370875_2373041_-\|tail	phage tail protein	A8ATW1	Listeria_phage	0.0e+00	94.3
WP_003733727.1\|2373053_2374622_-\|tail	phage tail family protein	A8ATW0	Listeria_phage	3.1e-304	99.2
WP_025370630.1\|2374618_2379418_-\|tail	phage tail tape measure protein	A8ATV9	Listeria_phage	0.0e+00	94.4
WP_072215797.1\|2379422_2379734_-	hypothetical protein	A0A0B5D116	Listeria_phage	2.5e-40	93.4
WP_025370631.1\|2379730_2380162_-	hypothetical protein	A0A0B5D0B8	Listeria_phage	2.4e-70	95.1
WP_049948463.1\|2380216_2380516_-	Ig-like domain-containing protein	Q9T1B0	Listeria_phage	1.1e-26	68.0
WP_025370633.1\|2380478_2380910_-	Ig domain-containing protein	A0A0B5CYK8	Listeria_phage	1.1e-57	82.1
WP_025370634.1\|2380914_2381286_-	hypothetical protein	A8ATV5	Listeria_phage	1.8e-61	95.9
WP_025370635.1\|2381282_2381600_-	HK97 gp10 family phage protein	A0A0B5CTS1	Listeria_phage	1.7e-52	97.1
WP_014930192.1\|2381589_2381955_-	hypothetical protein	A0A0B5D114	Listeria_phage	1.5e-65	100.0
WP_025370636.1\|2381954_2382308_-	hypothetical protein	A8ATV2	Listeria_phage	2.7e-59	96.6
WP_003753498.1\|2382308_2382464_-	hypothetical protein	A0A0B5CYK6	Listeria_phage	2.3e-15	86.3
WP_025370637.1\|2382477_2383350_-	hypothetical protein	A8ATV0	Listeria_phage	7.9e-161	99.0
WP_025370638.1\|2383372_2383927_-	hypothetical protein	A8ATU9	Listeria_phage	1.8e-78	90.8
WP_023552448.1\|2384022_2385066_-	hypothetical protein	A0A0B5D111	Listeria_phage	5.3e-196	97.7
WP_023552450.1\|2385070_2386630_-	hypothetical protein	A0A0B5D0A6	Listeria_phage	3.1e-293	97.3
WP_045131573.1\|2386644_2387991_-\|terminase	PBSX family phage terminase large subunit	A0A0B5CYJ6	Listeria_phage	1.5e-251	93.6
WP_003733717.1\|2387956_2388682_-	helix-turn-helix domain-containing protein	A0A0B5CTX0	Listeria_phage	4.4e-80	68.5
WP_003733718.1\|2388725_2388953_-	hypothetical protein	A0A0B5CTV3	Listeria_phage	2.4e-32	94.7
WP_025370640.1\|2389228_2389663_-	hypothetical protein	A8ASQ1	Listeria_phage	3.1e-57	76.4
WP_003733720.1\|2389727_2390225_-	Holliday junction resolvase RecU	A0A1L2JY30	Aeribacillus_phage	1.8e-32	49.3
WP_025370641.1\|2390214_2390397_-	hypothetical protein	A8ASP6	Listeria_phage	3.6e-15	79.3
WP_025370642.1\|2390418_2390901_-	single-stranded DNA-binding protein	A8ASP5	Listeria_phage	1.6e-70	83.8
WP_003733723.1\|2390901_2391156_-	hypothetical protein	A0A059T5G2	Listeria_phage	3.4e-40	92.8
WP_014601398.1\|2391334_2391796_-	hypothetical protein	D9J0I6	Brochothrix_phage	5.5e-12	29.9
WP_009930868.1\|2391792_2391960_-	hypothetical protein	NA	NA	NA	NA
WP_014601509.1\|2391960_2392170_-	hypothetical protein	A8ATE0	Listeria_phage	1.7e-32	100.0
WP_014601510.1\|2392166_2392568_-	hypothetical protein	A8ATD9	Listeria_phage	2.6e-74	100.0
WP_014929526.1\|2392645_2392792_-	hypothetical protein	A8ATZ0	Listeria_phage	1.7e-20	100.0
WP_014601511.1\|2392788_2393349_-	DUF1642 domain-containing protein	A8ATY9	Listeria_phage	9.4e-107	100.0
WP_014601512.1\|2393345_2393810_-	class I SAM-dependent methyltransferase	A0A059T693	Listeria_phage	6.9e-87	96.8
WP_115893015.1\|2394114_2394327_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_003731843.1\|2394464_2394680_-	hypothetical protein	NA	NA	NA	NA
WP_003731842.1\|2394691_2394859_-	hypothetical protein	A8ASN5	Listeria_phage	9.2e-18	80.0
WP_025370644.1\|2394863_2395319_-	class I SAM-dependent methyltransferase	A8ATY8	Listeria_phage	1.1e-81	91.4
WP_025370645.1\|2395315_2396290_-	phage replisome organizer N-terminal domain-containing protein	A8ASN4	Listeria_phage	1.9e-150	85.2
WP_014601516.1\|2396306_2396945_-	ERF family protein	A8ASN3	Listeria_phage	7.8e-81	76.7
WP_003747311.1\|2396949_2397426_-	siphovirus Gp157 family protein	A0A059T5F1	Listeria_phage	7.1e-71	93.0
WP_009930470.1\|2397422_2397617_-	hypothetical protein	A0A059T6E8	Listeria_phage	1.8e-28	95.3
WP_025370646.1\|2397918_2398107_-	hypothetical protein	A8ATY3	Listeria_phage	1.6e-26	93.5
WP_003769990.1\|2398214_2398430_-	hypothetical protein	Q9T176	Listeria_phage	6.1e-22	73.2
WP_003769992.1\|2398426_2398960_-	hypothetical protein	Q9T177	Listeria_phage	2.9e-81	88.1
WP_003769993.1\|2399084_2399864_-	phage antirepressor Ant	A0A059T6E7	Listeria_phage	2.0e-139	96.9
WP_025370647.1\|2399927_2400170_+	hypothetical protein	A0A059T7Q3	Listeria_phage	1.5e-37	98.8
WP_003727748.1\|2400162_2400324_-	hypothetical protein	A0A059T7X7	Listeria_phage	1.2e-19	98.1
WP_003769995.1\|2400355_2400637_-	hypothetical protein	Q9T180	Listeria_phage	1.4e-39	96.8
WP_003733634.1\|2400633_2400870_-	hypothetical protein	A0A059T5E9	Listeria_phage	3.3e-37	100.0
WP_157009380.1\|2401052_2401193_+	hypothetical protein	NA	NA	NA	NA
WP_014930211.1\|2401189_2401411_-	hypothetical protein	NA	NA	NA	NA
WP_003731220.1\|2401414_2401666_-	helix-turn-helix transcriptional regulator	A8ATX6	Listeria_phage	7.6e-40	100.0
WP_009911345.1\|2401814_2402123_+	helix-turn-helix transcriptional regulator	A8ATX5	Listeria_phage	7.8e-47	98.0
WP_009911346.1\|2402153_2402645_+	bacteriophage gp35-type protein	A8ATX4	Listeria_phage	1.1e-90	98.8
WP_025370648.1\|2402667_2402886_+	zinc-ribbon domain-containing protein	A0A059T6E3	Listeria_phage	1.3e-32	97.2
WP_003733640.1\|2402901_2403624_+	hypothetical protein	A0A059T7P9	Listeria_phage	2.8e-103	97.9
WP_003733641.1\|2403646_2404252_+	hypothetical protein	NA	NA	NA	NA
WP_003749252.1\|2404264_2404687_+	hypothetical protein	NA	NA	NA	NA
WP_025370649.1\|2404753_2406112_+	recombinase family protein	Q8LTD8	Listeria_phage	1.3e-237	90.0
WP_025370650.1\|2406102_2406579_+	competence protein ComK	NA	NA	NA	NA
WP_003739618.1\|2406633_2406981_-	helix-turn-helix transcriptional regulator	A0A0A7RTK4	Clostridium_phage	9.9e-06	40.7

DBSCAN-SWA_6

2548113 : 2555957

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722604.1\|2548113_2549085_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
WP_003722605.1\|2549092_2550061_-	YvcK family protein	A1IMD5	Streptococcus_phage	6.7e-68	43.3
WP_003722606.1\|2550062_2550938_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	29.7
WP_012952017.1\|2551045_2552776_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	3.0e-175	54.0
WP_012952018.1\|2552817_2553879_-	galactose mutarotase	NA	NA	NA	NA
WP_012952019.1\|2553895_2554879_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	5.8e-51	37.2
WP_003722610.1\|2554997_2555957_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7

DBSCAN-SWA_7

2836902 : 2846934

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012951084.1\|2836902_2839056_-	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	6.7e-44	34.1
WP_003732117.1\|2839079_2840852_-	DNA helicase RecQ	A0A2K9L3P7	Tupanvirus	6.3e-80	37.1
WP_003722118.1\|2841012_2842479_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	8.0e-97	40.0
WP_012951083.1\|2842766_2843297_-	ADP-ribose-binding protein	A0A0K1L687	Scale_drop_disease_virus	3.4e-29	49.3
WP_012951082.1\|2843354_2844965_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.2e-45	29.5
WP_072215787.1\|2845143_2845452_+	hypothetical protein	NA	NA	NA	NA
WP_009924391.1\|2845479_2846934_+	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	1.9e-50	30.3

Anti-CRISPR protein detection

Acr_ID: NZ_HG813247.1|WP_003723550.1|1284350_1284545_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NZ_HG813247.1|WP_003723553.1|1285791_1285929_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_HG813247.1|WP_003723550.1|1284350_1284545_-|hypothetical-protein

1284350_1284545_-

64 aa aa

1207651-1313203

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_HG813247_2	Orphan	2.1\|515197\|35\|NZ_HG813247\|PILER-CR,CRT	515197-515231	35	1259518-1259552	0
NZ_HG813247_2	Orphan	2.6\|515517\|36\|NZ_HG813247\|PILER-CR,CRT	515517-515552	36	1258370-1258405	0

1. spacer 2.1|515197|35|NZ_HG813247|PILER-CR,CRT matches to NZ_HG813247 position: 1259518-1259552, mismatch: 0

acagatcaaactccggaagggtgattgtaaatggc	CRISPR spacer
acagatcaaactccggaagggtgattgtaaatggc	Protospacer
***********************************

2. spacer 2.6|515517|36|NZ_HG813247|PILER-CR,CRT matches to NZ_HG813247 position: 1258370-1258405, mismatch: 0

aaaataggaggaaataaattatgactatcaaattaa	CRISPR spacer
aaaataggaggaaataaattatgactatcaaattaa	Protospacer
************************************

NZ_HG813247.1|WP_003723553.1|1285791_1285929_-|hypothetical-protein

1285791_1285929_-

45 aa aa

1207651-1313203

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_HG813247_2	Orphan	2.1\|515197\|35\|NZ_HG813247\|PILER-CR,CRT	515197-515231	35	1259518-1259552	0
NZ_HG813247_2	Orphan	2.6\|515517\|36\|NZ_HG813247\|PILER-CR,CRT	515517-515552	36	1258370-1258405	0

1. spacer 2.1|515197|35|NZ_HG813247|PILER-CR,CRT matches to NZ_HG813247 position: 1259518-1259552, mismatch: 0

acagatcaaactccggaagggtgattgtaaatggc	CRISPR spacer
acagatcaaactccggaagggtgattgtaaatggc	Protospacer
***********************************

2. spacer 2.6|515517|36|NZ_HG813247|PILER-CR,CRT matches to NZ_HG813247 position: 1258370-1258405, mismatch: 0

aaaataggaggaaataaattatgactatcaaattaa	CRISPR spacer
aaaataggaggaaataaattatgactatcaaattaa	Protospacer
************************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_HG813247

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information