CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_HG939456	Streptococcus agalactiae COH1	2 crisprs	cas3,DinG,RT,cas9,cas1,cas2,csn2,csm6,DEDDh,csa3	1	13	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_HG939456_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_HG939456_1

871649-872081

TypeII

II-A

Consensus_repeat	Method
AGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRT

6 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_HG939456_1

>merge|NZ_HG939456|1|871649-872081|CRISPRCasFinder,CRT
GGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACATTTGACAAACATTGAACTTAAAAGAAACTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACCTGTTCATAAAGAGCAACTAGTGGCAACATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTGCTAAAAGGTAAATTTAACATTCCAGGTAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTATTTGATAGCGGTAACGGGTCATATACAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACGATAAAAAGTGGGAGCTGAATTAAAAGGCAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACATTTGAACGATTTTTATATTCCTGATATGTGTTTTAGAGCTGTGCGGTTATTATGCTAGGGCACCG

>NZ_HG939456|1|1|871649-872015|CRISPRCasFinder
GGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTTGACAAACATTGAACTTAAAAGAAAC
TGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CTGTTCATAAAGAGCAACTAGTGGCAACA
TGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGCTAAAAGGTAAATTTAACATTCCAGGT
AGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TATTTGATAGCGGTAACGGGTCATATACA
AGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GATAAAAAGTGGGAGCTGAATTAAAAGGC
AGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>NZ_HG939456|1|1|871650-872081|CRT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTTGACAAACATTGAACTTAAAAGAAACT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CTGTTCATAAAGAGCAACTAGTGGCAACAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGCTAAAAGGTAAATTTAACATTCCAGGTA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TATTTGATAGCGGTAACGGGTCATATACAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GATAAAAAGTGGGAGCTGAATTAAAAGGCA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTTGAACGATTTTTATATTCCTGATATGT
GTTTTAGAGCTGTGCGGTTATTATGCTAGGGCACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_HG939456.1\|WP_000438312.1\|872637_873054_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_HG939456.1\|WP_000065314.1\|882510_883614_+\|DUF2974-domain-containing-protein	unknown	unknown	gnl\|CDD\|371412
NZ_HG939456.1\|WP_000122196.1\|870555_870897_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_HG939456.1\|WP_000665411.1\|879132_879570_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_HG939456.1\|WP_000653357.1\|864639_865296_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_HG939456.1\|WP_000168912.1\|879718_882511_+\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NZ_HG939456.1\|WP_001019130.1\|873189_875022_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_HG939456.1\|WP_001241816.1\|861534_861915_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131381
NZ_HG939456.1\|WP_000929494.1\|869689_870559_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_HG939456.1\|WP_000180008.1\|878000_878660_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224336
NZ_HG939456.1\|WP_000238430.1\|872359_872497_+\|hypothetical-protein	unknown	unknown	unknown
NZ_HG939456.1\|WP_000621139.1\|878668_879133_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_HG939456.1\|WP_001040110.1\|865575_869688_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_HG939456.1\|WP_000590710.1\|870883_871549_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_HG939456.1\|WP_000146567.1\|883731_884370_-\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_HG939456.1\|WP_000159234.1\|861138_861510_+\|YbgA-family-protein	unknown	unknown	gnl\|CDD\|377982
NZ_HG939456.1\|WP_000678305.1\|875267_877901_+\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|275380
NZ_HG939456.1\|WP_000323544.1\|863879_864650_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_HG939456.1\|WP_000914665.1\|862007_863138_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_HG939456.1\|WP_000523795.1\|863141_863879_+\|acyl-ACP-thioesterase	unknown	unknown	gnl\|CDD\|366738

Protein	Function_ID	Function_description	E-value
NZ_HG939456.1\|WP_000438312.1\|872637_873054_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	1.21474e-79
NZ_HG939456.1\|WP_000065314.1\|882510_883614_+\|DUF2974-domain-containing-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	1.12954e-104
NZ_HG939456.1\|WP_000122196.1\|870555_870897_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.83127e-50
NZ_HG939456.1\|WP_000665411.1\|879132_879570_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	9.78399e-86
NZ_HG939456.1\|WP_000653357.1\|864639_865296_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	9.75792e-52
NZ_HG939456.1\|WP_001019130.1\|873189_875022_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_HG939456.1\|WP_001241816.1\|861534_861915_+\|hypothetical-protein	gnl\|CDD\|131381	TIGR02328, TIGR02328, conserved hypothetical protein. Members of this protein are found in a small number of taxonomically well separated species, yet are strongly conserved, suggesting lateral gene transfer. Members are found in Treponema denticola, Clostridium acetobutylicum, and several of the Firmicutes. The function of this protein is unknown. [Hypothetical proteins, Conserved].	6.45558e-80
NZ_HG939456.1\|WP_000929494.1\|869689_870559_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.45885e-137
NZ_HG939456.1\|WP_000180008.1\|878000_878660_+\|HD-domain-containing-protein	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	1.30028e-33
NZ_HG939456.1\|WP_000168912.1\|879718_882511_+\|cation-transporting-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NZ_HG939456.1\|WP_000621139.1\|878668_879133_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.90455e-18
NZ_HG939456.1\|WP_001040110.1\|865575_869688_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_HG939456.1\|WP_000590710.1\|870883_871549_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	4.57126e-122
NZ_HG939456.1\|WP_000146567.1\|883731_884370_-\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	1.14428e-70
NZ_HG939456.1\|WP_000159234.1\|861138_861510_+\|YbgA-family-protein	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	6.08694e-28
NZ_HG939456.1\|WP_000678305.1\|875267_877901_+\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	2.83221e-22
NZ_HG939456.1\|WP_000323544.1\|863879_864650_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19143e-132
NZ_HG939456.1\|WP_000914665.1\|862007_863138_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_HG939456.1\|WP_000523795.1\|863141_863879_+\|acyl-ACP-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	3.68196e-111

>NZ_HG939456.1|WP_000590710.1|870883_871549_+|type-II-A-CRISPR-associated-protein-Csn2
MIKINFPILDEPLVLSNATILTIEDVSVYSSLVKHFYQYDVDEHLKLFDDKQKSLKATELMMVTDILGYDVNSAPILKLIHGDLENQFNEKPEVKSMVEKLAATITELIAFECLENELDLEYDEITILELIKALGVKIETQSDTIFEKCFEIIQVYHYLTKKNLLVFVNSGAYLTKDEVIKLCEYINLMQKSVLFLEPRRLYDLPQYVIDKDYFLIGENMV
>NZ_HG939456.1|WP_000122196.1|870555_870897_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETVEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNTANNAMIGRLKVNNPKKGNITLLTVTEKQFARMVYLHGERNTSVANFDSRLVFLGDSYDQD
>NZ_HG939456.1|WP_000929494.1|869689_870559_+|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLVFKDSYQTEMIHLSEIDILIMETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARYDSSLQLSRQMSWIEDVKADVWTSIIAQKILNQSFYLGECSFFEKSQSIMNLYHDLESFDTSNREGHAARIYFNTLFGNDFSREHDNPINAGLDYGYSLLLSMFAREVVKCGCMTQFGLKHANQFNQFNLASDIMEPFRPIVDRIIYENRQSDFVKMKRELFSMFSETYSYDGKEMYLSNIVSDYTKKVIKSLNSDGNGIPEFRI
>NZ_HG939456.1|WP_001040110.1|865575_869688_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNKPYSIGLDIGTNSVGYSVVTDDYKVPAKKMRVLGNTDKEYIKKNLIGALLFDGGNTASDRRLKRTARRRYTRRRNRILYLQEIFAEEMSKVDDSFFHRLEDSFLVEDDKRGSKYPIFATMQEEKDYHEKFPTIYHLRKELADKKEKANLRLVYLALAHIIKFRGHFLIEDDSFDVRNTDIQRQYQAFLEIFDTTFENNHLLSQNIDVEGILTDKISKSAKKDRILAQYPNQKSTGIFAEFLKLIVGNQADFKKHFNLEDKTPLQFAKDSYDEDLENLLGQIGDEFADLFSVAKKLYDSVLLSGILTVTDLSTKAPLSASMIQRYDEHREDLKQLKQFVKASLPEKYQEIFTDSSKDGYAGYIEGKTNQGAFYKYLSKLLTKQEGSEYFLEKIKNEDFLRKQRTFDNGSIPHQVHLTELKAIIRRQSEYYPFLKENLDRIEKILTFRIPYYVGPLAREKSDFAWMTRKTDDSIRPWNFEELVDKEASAEAFIHRMTNNDLYLPEEKVLPKHSLIYEKFTVYNELTKVRYKNEQGETYFFDSNIKQEIFDGVFKEHRKVSKKKLLDFLAKEYEEFRIVDVIGLDKENKAFNASLGTYHDLKKILDKDFLDNPDNESILEDIVQTLTLFEDREMIKKRLENYKDLFTESQLKKLYRRHYTGWGRLSAKLINGIRDKESQKTILDYLISDGRANRNFMQLIHDDGLSFKPIIDKAQAGSHSDNLKEVVGELAGSPAIKKGILQSLKIVDELVKVMGYEPEQVVVEMARENQTTNQGRRNTRQRYKLLEEGVKNLASDLNGNILKEYPTDNQALQNERLFLYYLQNGRDMYTGEALDIDNLSQYDIDHIVPQAFIKDDSIDNRVLVSSAKNRGKSDNVPSIDIVKARKAFWKKLLDAKLMSQRKYDNLTKAERGGLTSDDKARFIQRQLVETRQITKHVARILDERFNNELDSKGRRIRKVKIVTLKSNLVSNFRKEFGFYKIREVNDYHHAHDAYLNAVVAKAILTKYPQLEPEFVYGDYPKYNSYKTRKSATEKLFFYSNIMNFFKTKVTLADGTVVVKDDIEVNNDTGEIVWDKKKHFATVRKVLSYPQVNIVKKTEIQTGGFSKESILAHGNSDKLIPRKTKDIYLDPKKYGGFDSPIVAYSVLVVADIKKGKAQKLKTVTELLGITIMERFRFEKNPSAFLESKGYLNIRDDKLMILPKYSLFELENGRRRLLASAGELQKGNELALPTQYMKFLYLASRYNELKGKPEEIEQKQEFVVQHVSYFDDILQIINDFSNRVILADANLEKINKLYQDNKENISVDELANNIINLFTFTSLGAPAAFKFFDKIVDRKRYTSTKEVLNSTLIHQSITGLYETRIDLGKLGED
>NZ_HG939456.1|WP_000653357.1|864639_865296_+|TIGR01906-family-membrane-protein
MKDKLLVVLTWIWIISLATLATIYIAWLIYPIEIQFLKLEKVVYLKAETIYYNFNKLMIYLTHPFISDLNMPSFPSSEDGLKHFADVKYLFTLAHGLFVILTFPVIYFLRRGWKQKSIFLYEGFFKIAIMLPIFIVVCAFLLGFDQFFTLFHEVLFPGDSTWQFNPLTDPVIWILPETFFLHCFIIFLLIYETITIILLIIGRKHLKLRKYKNKMQAL
>NZ_HG939456.1|WP_000323544.1|863879_864650_+|TIGR01457-family-HAD-type-hydrolase
MAYKGYLIDLDGTIYKGKSRIPAGERFIERLQEKGIPYMLVTNNTTRTPESVQEMLRGFNVETPLETIYTATMATVDYMNDMNRGKTAYVIGEEGLKKAIADAGYVEDTKNPAYVVVGLDWNVTYDKLATATLAIQNGALFIGTNPDLNIPTERGLLPGAGSLNALLEAATRIKPVFIGKPNAIIMNKALEILNIPRNQAVMVGDNYLTDIMAGINNDIDTLLVTTGFTTVEEVPDLPIQPSYVLASLDEWTFNEG
>NZ_HG939456.1|WP_000523795.1|863141_863879_+|acyl-ACP-thioesterase
MGLLYRETYEVPFYESDTNHYMKLPQLLALALQISAKQSLKLGIGDDIVFKRYGLVWVVTDYIIDIERLPKHAEKIVIETEAKAHNKLLCYRYFYIYGEDGQKIITISSAFVLMDFKTRKIHPVLDDITSIYQSQRIKKVIRGPKYHPIGDSKVKQYHVRYFDLDMNGHVNNSKYLEWMYDVLDLDFLSSHIPKKIDLKYIKEIQYGTDIKSHWYQDGLVTRHDIIGGDAIHAQARIEWQEKKED
>NZ_HG939456.1|WP_000914665.1|862007_863138_+|oxygen-independent-coproporphyrinogen-III-oxidase
MLKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLQALIREFRSYDITELRTLYIGGGTPTSISAVQLDYLLTELSRDLNLNTLEEFTIEANPGDLTVDKIEVLQKSAVNRVSLGVQTFNDKHLKRIGRSHNEVQIYSTIDALKTAGFQNISIDLIYALPGQTMDDVRSNVAKALSLNIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEMFEYIISEMERNGFEHYEISNFTKPGFESRHNLMYWDNVEYYGVGAGASGYLDGIRYRNRGPIQHYLKGVSEGNARLSEEVLSKNEMMEEELFLGLRKKKGVSIGKFEQKFGTSFEKRYGQIVQELQSDGLLKENNGFIQMTKKGLFLGDTVAEKFIVE
>NZ_HG939456.1|WP_001241816.1|861534_861915_+|hypothetical-protein
MRLWHQDIIELLPRQQLLGQHRECCALRGNGWGRKHETVDYVFRYSPYRLFAYHQLVMEEMMERGYRVSKEWLIAEYRGMKCPRYDTLNPVDLETPIYPEHNQDYLQECLWNLKAKGIDLPINKIK
>NZ_HG939456.1|WP_000159234.1|861138_861510_+|YbgA-family-protein
MTKEAELLWAKHKYLVLSKSQKIYLDIRQTLKSPNCTVLDVQSLIDQAVLLEESPSQVTNAYMHIWGYFKNKAERQEKEEFLTLLEKYRKTGYQRRKLLAFLKQLLAKYPNSYLQNSSIFEEE
>NZ_HG939456.1|WP_000238430.1|872359_872497_+|hypothetical-protein
MVKGLDCSTLYLIISLTALVLLVIAGVSLSLILASLQGKQWRTYP
>NZ_HG939456.1|WP_000438312.1|872637_873054_+|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVKRGFIGEVISRIERRGFSIDRLEVRHADADILKRHYAELTDRPFFPTLVDYMTSGPVIIGVISGEEVISTWRTMMGSTNPKDALPGTIRGDFAQAPSPNQATCNIVHGSDSPESAAREIAIWFNN
>NZ_HG939456.1|WP_001019130.1|873189_875022_+|elongation-factor-4
MNIEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRAEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGEVDAPLQALIFDSVYDAYRGVILQVRIVNGMVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVADTRVGDTITLANNPAIDPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSEFPDPTRVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDDKK
>NZ_HG939456.1|WP_000678305.1|875267_877901_+|pneumococcal-type-histidine-triad-protein
MKGQKIIALAGLVLSCHFALTACHTQEHKNSYHIKTKQVAKKKANKKKVSVKESHKKRKGVAGVDFPTDDGFLLTKDSKILSHTDSGIVVAHGNHSHFIFYSDLKGSKFSYLIPNANAKTNKNQAVRNFKAGAVAVNTLNDGYVFNPADIVSEDANGYVVRHGDHFHYIPKASLSQQKQVQASRAVSRLGNQSNSHYRVNSSKIAGLHYPTSDGFLFNGRGIKGTTPTGILVEHHNHLHFISFADLRKGGWGSIADRYQPQKKADSKKQSPSSKKPRNENTLPKDIKDKLAYLARELHLDISRIRVLKTLNGEIGFEYPHDDHTHVIMAKDIDLSKPIPNPHHDDEDHHKGHHHDESDHKHEEHEHTKSNKLSDENQKKLIYLAEKLGLNPNQIEVLTSEDGSIIFKYPHDDHSHTIASKDIEIGKPIPDGHHDHSHAKDKVGMATLKQIGFDDEIIQDILHADAPTPFPSNETNPEKMRQWLATVTKINIGQRTNPFQRFGLSLMPNIEVLGIGFTPINDMTPVLQFKKLKQLWMTNTGITDYSFLDKMPLLEGLDISQNGIKDLSFLTKYKQLSLIAAANNGITSLKPLAELPNLQFLVLSHNNISDLTPLSNLTKLQELHLDHNNVKNLSALSGKKDLKVLDLSNNKSADLSTLKTTSLETLLLNETNTSNLSFLKQNPKVSNLTINNAKLSSLDGIEESDEIVKVEAEGNQIKSLVLKNKQGSLKFLNVTNNQLTSLEGVNNYTSLETLSVSRNKLKSLDIKTPNKTVTNLDFSHNNVPTSQLKLNEKNIPEAVAKNFPAVVEGSMVGNGSLAEKAAMASKEDKQVSDNTNHQKNTEKSAQANADSKKENPKTHDEHHDHEETDHAHVGHHHH
>NZ_HG939456.1|WP_000180008.1|878000_878660_+|HD-domain-containing-protein
MTMVKREDVILNATENMVYHKLKNDPSGHDWFHIVRVRNLAVELAHKEGANTFICQMAALLHDIIDDKICQDSKQASYELTQWLYSQDLAIAEVEHILDILENISFKAGTGLTMKTLEGQIVQDADRLDAMGAIGIARTMAYSGSKGRLIHDPNLKPRENLTLEEYRNGQDTAIMHFYEKLLKLKDLMNTKQGKMLAQKRHDFLELYLAEFYAEWNGKG
>NZ_HG939456.1|WP_000621139.1|878668_879133_+|GNAT-family-N-acetyltransferase
MIRRAKEKDLPAIAELLKQILVLHHGVRPDIFHTRGSKFSKEQLKEMLMDESRPIFVYESDEGKVVAHLFLQLQEKRDLPRKSFKTLYIDDLCIDEEVRGQQIGQKLMDFARQYAKKHGCYNITLNVWNDNQRAVSFYEKLGFKPQQTQMEEIL
>NZ_HG939456.1|WP_000665411.1|879132_879570_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MKETQEELRQRIGHTAYQVTQNSATEHAFTGKYDDFFEEGIYVDIVSGEVLFSSLDKFQSGCGWPAFSKPIENRMVTNHQDHSHGMHRIEVRSRQADSHLGHVFNDGPVDAGGLRYCINSAALDFIPYDQMAKRGYGDYLSLFDE
>NZ_HG939456.1|WP_000168912.1|879718_882511_+|cation-transporting-P-type-ATPase
MASTNNVSDTNTRFAKEELEEVFEELGTTQGGLSDEEVAVRQKKYGLNLLSEVKQESIILLFLKNFTSLMAILLWVGGFVAIVSNSLELGLAIWMVNVINGIFSFIQEYRASQATQALKKMLPSYSRVLRKSSEEKVLSEQLVPGDIVLIEEGDCISADGRLIKTTDLQVNQSALTGESNPIYKDSNVENYQSKTLIECDNMVFAGTTVSSGSATMVVTAIGMQTQFGQIADLTQGMKSEKSPLQRELDRLTKQISIISITVGIIFFLAATFFVKEPVSKSFIFALGMIVAFIPEGLLPTVTLSLAMAVQRMAKEHALVKKLSSVETLGATSVICSDKTGTLTQNEMTVNHLWQNGKSYQVTGLGYAPEGQILFEGDNICFGNSDRGDLEKLIRFAHLCSNAQVLPPNDDRSTYTVLGDPTEACLNVLLEKSGINIQENRKFAPRLKELPFDSVRKRMTTIHSLGGDEKDKKISITKGAPKEILDLSDYVLSDGKVIPLNKEERNKIQLANDTFAKDGLRVLAVSYCDIEGFSKEQWTQENLEQHMVFIGLIAMSDPPREGVREAIDKCHAASIRIIMVTGDYGLTALSIAKNIGIIRNDDAKVISGLELSEMTDSQLKKELSGEVVFARVAPEQKYRVVTILQEMGEVVAVTGDGVNDAPALKKSDIGVAMGVTGTDVAKESADMILTDDHFASIVHAVEEGRAVYQNIKKFLTYIFNSNTPEAVPSAFFLFSKGFIPLPLTVMQILAVDLGTDMLPALGLGVEPPETDVMNRPPRRLTDRLLDKGLLIKSFLWYGTIESVLAMGGFFWAHYLRYGNFTFFVANGIPYREATTMTLGAIIFSQIGMVMNSRTSYQSIKTLSIFGNKLINFGIIMEILAFLVLVYVPLFHNLFNTASLGLSHWLYLISCPFIMIGLDEVRKLFSSRKNKR
>NZ_HG939456.1|WP_000065314.1|882510_883614_+|DUF2974-domain-containing-protein
MSNIITYLKNNSNLTFDELALNDVDILCLNEFGYISFEKLINTTEMKSVLVCELYHEYLQTMAKSYSFMFTSQRHDLCQLMMTSKRFKNLTLSYYQAEISLEFEKQFAAMVFTIPNIDYHQVVFRGTDANLIGWKEDFKLTYMREISAHRSAIKYLNTILPYFDKVVLSGHSKGGNLALYAAMFTKPDLKAKIDLIWLIDSPGLQKTLLPTTEYKTTKQKCIRLLPEESIVGMMLYSDIEPLIISSNARGILQHDVTTWEIQEPAILKTGAGLSLKSICFEKTFQQWMAELKSQERKLFFDLLFDSFLSSGVSSLDDFNLASRAKMMKAFHSFRELDDDKKRLFNKSLKLLVTIFWGAYHDNSRETK
>NZ_HG939456.1|WP_000146567.1|883731_884370_-|CatB-related-O-acetyltransferase
MASILKKHLEKRLELKNDPMRTDMSTGASYPKYGFSVGKYTYGYQQFFYEGVNLKEIGAFCSIAQNVTITGMNHPTDHITTNPFIYYKSRGFINEDRADLIDEKKNGKVIIGNDVWIGTNVTILPSVTIGNGAIIEAGSVITKDIPDYAVVAGTPAKIIKYRFSEEEITLLNASQWWNWSDEAIKEHISEFSDKREFFNTLKSISENKNHKL

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Crispr_ID: NZ_HG939456_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_HG939456_2

1934523-1934708

Orphan

Consensus_repeat	Method
CTGGCTTANCNTCTGGTT	CRT

4 spacers

The CRISPR arrays of NZ_HG939456_2

>merge|NZ_HG939456|2|1934523-1934708|CRT
CTGGCTTAACGTCTGGTTTAACTTCTGGTTTAGCCTCTGGTTTGGCTTCTGGCTTAGCCTCTGGCTTAACGTCTGATTTAACTTCTGGCTTAGCCTCTGGTTTGGCCTCTGGCTTAACGTCTGGTTTAACTTCTGGCTTAGCCTCTGGTTTGGCCTCTGGCTTAACGTCTGGTTTAACTTCTGGTT

>NZ_HG939456|2|2|1934523-1934708|CRT
CTGGCTTAACGTCTGGTT	TAACTTCTGGTTTAGCCTCTGGTTTGGCTT
CTGGCTTAGCCTCTGGCT	TAACGTCTGATTTAACTT
CTGGCTTAGCCTCTGGTT	TGGCCTCTGGCTTAACGTCTGGTTTAACTT
CTGGCTTAGCCTCTGGTT	TGGCCTCTGGCTTAACGT
CTGGTTTAACTTCTGGTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_HG939456.1\|WP_000953623.1\|1930005_1930851_-\|patatin-family-protein	unknown	unknown	gnl\|CDD\|132847
NZ_HG939456.1\|WP_000074729.1\|1928715_1929963_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_HG939456.1\|WP_001159691.1\|1943668_1944871_-\|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl\|CDD\|224883
NZ_HG939456.1\|WP_000222146.1\|1931055_1932252_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|133037
NZ_HG939456.1\|WP_000730410.1\|1922211_1923600_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_HG939456.1\|WP_000160598.1\|1927107_1928274_+\|IS30-like-element-ISSag9-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_HG939456.1\|WP_000903266.1\|1923692_1924301_+\|hypothetical-protein	unknown	unknown	unknown
NZ_HG939456.1\|WP_000764797.1\|1936605_1938927_-\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|223815
NZ_HG939456.1\|WP_000145176.1\|1924390_1926892_-\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NZ_HG939456.1\|WP_000409543.1\|1932316_1933522_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|133037
NZ_HG939456.1\|WP_001093377.1\|1916581_1921297_+\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173801
NZ_HG939456.1\|WP_000077169.1\|1941689_1942901_-\|phosphopentomutase	unknown	unknown	gnl\|CDD\|235430
NZ_HG939456.1\|WP_000057521.1\|1936404_1936557_-\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|234783
NZ_HG939456.1\|WP_000497678.1\|1936195_1936369_-\|preprotein-translocase-subunit-SecE	unknown	unknown	gnl\|CDD\|223762
NZ_HG939456.1\|WP_000010475.1\|1938970_1939855_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_HG939456.1\|WP_001182060.1\|1944891_1945671_-\|uridine-phosphorylase	unknown	unknown	gnl\|CDD\|350167
NZ_HG939456.1\|WP_000887149.1\|1933568_1934108_-\|transcription-termination/antitermination-protein-NusG	unknown	unknown	gnl\|CDD\|180161
NZ_HG939456.1\|WP_001125579.1\|1945830_1946568_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_HG939456.1\|WP_000453153.1\|1942967_1943639_-\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234784
NZ_HG939456.1\|WP_000459240.1\|1939879_1941520_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226987

Protein	Function_ID	Function_description	E-value
NZ_HG939456.1\|WP_000953623.1\|1930005_1930851_-\|patatin-family-protein	gnl\|CDD\|132847	cd07208, Pat_hypo_Ecoli_yjju_like, Hypothetical patatin similar to yjju protein of Escherichia coli. Patatin-like phospholipase similar to yjju protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins, and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	2.37781e-121
NZ_HG939456.1\|WP_000074729.1\|1928715_1929963_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.36923e-69
NZ_HG939456.1\|WP_001159691.1\|1943668_1944871_-\|NupC/NupG-family-nucleoside-CNT-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	2.06818e-155
NZ_HG939456.1\|WP_000222146.1\|1931055_1932252_+\|hypothetical-protein	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	4.07197e-67
NZ_HG939456.1\|WP_000730410.1\|1922211_1923600_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.15512e-45
NZ_HG939456.1\|WP_000160598.1\|1927107_1928274_+\|IS30-like-element-ISSag9-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	7.66585e-35
NZ_HG939456.1\|WP_000010475.1\|1938970_1939855_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	3.78283e-84
NZ_HG939456.1\|WP_000764797.1\|1936605_1938927_-\|penicillin-binding-protein	gnl\|CDD\|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	0
NZ_HG939456.1\|WP_000145176.1\|1924390_1926892_-\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_HG939456.1\|WP_000409543.1\|1932316_1933522_+\|hypothetical-protein	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	3.51587e-72
NZ_HG939456.1\|WP_001093377.1\|1916581_1921297_+\|S8-family-serine-peptidase	gnl\|CDD\|173801	cd07475, Peptidases_S8_C5a_Peptidase, Peptidase S8 family domain in Streptococcal C5a peptidases. Streptococcal C5a peptidase (SCP), is a highly specific protease and adhesin/invasin. The subtilisin-like protease domain is located at the N-terminus and contains a protease-associated domain inserted into a loop. There are three fibronectin type III (Fn) domains at the C-terminus. SCP binds to integrins with the help of Arg-Gly-Asp motifs which are thought to stabilize conformational changes required for substrate binding. Peptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.37759e-89
NZ_HG939456.1\|WP_000077169.1\|1941689_1942901_-\|phosphopentomutase	gnl\|CDD\|235430	PRK05362, PRK05362, phosphopentomutase; Provisional.	0
NZ_HG939456.1\|WP_000057521.1\|1936404_1936557_-\|50S-ribosomal-protein-L33	gnl\|CDD\|234783	PRK00504, rpmG, 50S ribosomal protein L33; Validated.	2.53308e-18
NZ_HG939456.1\|WP_000497678.1\|1936195_1936369_-\|preprotein-translocase-subunit-SecE	gnl\|CDD\|223762	COG0690, SecE, Preprotein translocase subunit SecE [Intracellular trafficking and secretion].	5.81702e-09
NZ_HG939456.1\|WP_001182060.1\|1944891_1945671_-\|uridine-phosphorylase	gnl\|CDD\|350167	cd17767, UP_EcUdp-like, uridine phosphorylases similar to Escherichia coli Udp and related phosphorylases. Uridine phosphorylase (UP) is specific for pyrimidines, and is involved in pyrimidine salvage and in the maintenance of uridine homeostasis. In addition to E. coli Udp, this subfamily includes Shewanella oneidensis MR-1 UP and Plasmodium falciparum purine nucleoside phosphorylase (PfPNP). PfPNP is an outlier in terms of genetic distance from the other families of PNPs. PfPNP is catalytically active for inosine and guanosine, and in addition, has a weak UP activity. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	4.65794e-137
NZ_HG939456.1\|WP_000887149.1\|1933568_1934108_-\|transcription-termination/antitermination-protein-NusG	gnl\|CDD\|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	3.00072e-83
NZ_HG939456.1\|WP_001125579.1\|1945830_1946568_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.9213e-33
NZ_HG939456.1\|WP_000453153.1\|1942967_1943639_-\|deoxyribose-phosphate-aldolase	gnl\|CDD\|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	5.32157e-109
NZ_HG939456.1\|WP_000459240.1\|1939879_1941520_-\|hypothetical-protein	gnl\|CDD\|226987	COG4640, COG4640, Predicted membrane protein [Function unknown].	3.13723e-08

>NZ_HG939456.1|WP_000887149.1|1933568_1934108_-|transcription-termination/antitermination-protein-NusG
MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIPTQTVNVEKNGKTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPTPLLEEEIRSILISMGQTVDVFDTNIKEGDVVQIIDGAFIGQEGRVVEIENNKVKLMINMFGSETQAELELYQVAEL
>NZ_HG939456.1|WP_000409543.1|1932316_1933522_+|hypothetical-protein
MEKAVALAVDSNYLDKALVTIKSICVYNRNITFYLFNQDTPVEWVRNINRKLEPLGSKLINVKIYNYDIAHLTTFLTVSTWFRLFLADYIPSSRVLYLDSDIIVNTNLDYLFELDFKGHYLAAVKDPHKNEEGGFNAGMLLANLELWREDGLTKTLLKTAEELHRVVKTGDQSILNIVCHNRWLSLNKTWNFQTYDVVSRYNHRSYLYLNIENRTPNIIHFLTSDKPWNENSVARFRELWWYYFQLDFCQLTGKQRKVISYEKSMELLSVSDIHLFTLTSSDNLEHIESLICRCPTVQFHIGAYTTVSNKLSKLEQYPNVLVYPELIEARIEKLITLATAYLDINHGPEVGNILQRVHLKQKPIYSFNNTSHQENITKHIVNHNSIDNMVVLINELNLNQL
>NZ_HG939456.1|WP_000222146.1|1931055_1932252_+|hypothetical-protein
MTYQKTVVLAGDYSYIRQIETTLKSLCVYHENLSIFIFNQDIPQEWFLAMKDRVGQTGNQIQDVKLFHDHLSPKWENKKLNHINYMTYARYFIPQYISADTVLYLDSDLVVTTNLDNLFQISLDNAYLAAVPALFGLGYGFNAGVMVINNQRWRQENMTIKLIEKNQKEIENANEGDQTILNRMFENQVIYLDDTYNFQIGFDMGAAIDGHKFIFDIPITPLPKIIHYISGIKPWQTLSNMRLREVWWHYNLLEWSSIISSKKVFGLDHPIKTQNYRLNFLIVTTSDCIPSISELVTALPDCLFHIAAPTVMSDILISLLAFENIRLHKTYTPPIIDKLLAEADIYLDINVFGKMEGILQKMSQSEKPILTTRECNSQLVPETVFASIDDLINYLQSI
>NZ_HG939456.1|WP_000953623.1|1930005_1930851_-|patatin-family-protein
MLSVGLVLEGGGMRGLYTAGVLDAFLDAGIKIDGIVSVSAGALFGVNFVSRQRERALRYNKKYLSHPEYMSLRSWLRTGNFVNKDFTYYEVPMKLDVFDDEAFKKSSIDFYVVATEMTSGKPEYFKIDSVFEQMEILRASSALPVVSKMVDWQGKKYLDGGLSDSIPVDFARGLGFDKLIVVMTRPLNYQKKPSSGRLYKTLYRKYPNFVKTASNRYQQYNNSLEKVMSLEKTGDLFAIRPSKSLVIGRLEKNPDKLDSIYQLGMKYAKSVMPELNSYLMK
>NZ_HG939456.1|WP_000074729.1|1928715_1929963_+|MFS-transporter
MSPLNINKNNWRALIAAIVASGTDDLNIMFLAFSMSTIITDLHLSAAQAGWIGTITNLGMLVGGLIFGLLADRYNKFKVFKWTILIFSIATGLVFFTTNLSYLYIMRFIAGIGVGGEYGIAIAIMAGIVPANKMGRISSLNGIAGQVGSISSALLAGWLAPALGWRGLFLFGLLPIVLVLWMQFAIDDKDILDQYNTDADDEPLDISIKALFDTPVLATQSLALMVMTTVQIAGYFGMMNWLPTIIQTNLNVSVKNSSLWMIATIFGMCLGMLVFGQLLDKFGPRLVYGCFLLSSAICVYLFQFATTMPSMIIGGAVVGFFVNGMFAGYGAMITRLYPHHIRSTANNLILNVGRAIGGFSSVIIGMILDVSNVSMVMLFLASLYIVSFLSMLSIKQLKRQKYHTNLTQLDVKPTD
>NZ_HG939456.1|WP_000160598.1|1927107_1928274_+|IS30-like-element-ISSag9-family-transposase
MTKHKHLTLSDRNDIQSGLDRGETFKAIGLNLLKHPTTIAKEVKRNKQLRESTKDCLDCPLLRKAPYVCNGCPKRRINCGYKKTFYLAKQAQRNYEKLLVESREGIPLNKETFWKIDRVLSNGVKKGQRIYHILKTNDLEVSSSTVYRHIKKGYLSITPIDLPRAVKFKKRRKSTLPPIPKAIKEGRRYEDFIEHMNQSELNSWLEMDTVIGRIGGKVLLTFNVAFCNFIFAKLMDSKTAIETAKHIQVIKRTLYDNKRDFFELFPVILTDNGGEFARVDDIEIDVCGQSQLFFCDPNRSDQKARIEKNHTLVRDILPKGTSFDNLTQEDINLALSHINSVKRQALNGKTAYELFSFTYGKDIASILGIEEITAEDVCQSPKLLKDKI
>NZ_HG939456.1|WP_000145176.1|1924390_1926892_-|leucine--tRNA-ligase
MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFKLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQVLTASGESISYVPWPSYDESKLVENEIEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVVK
>NZ_HG939456.1|WP_000903266.1|1923692_1924301_+|hypothetical-protein
MLHSKKIHSLSLIAVLSLATYTSLQPNHVAAEQSQKTSTVHMSQKTIEHKLKVADKEAAPLYAKIDHIQRHIEVKKAKDLKVIELYINKDINQLEKQNKRLLTKFYTSIDNQTWDSTSEVKKLIDKTTLSTNEKDRLKLYFEQRAYLETRLNDRYQKFDNSIENQNKELKILTSKIEKIYQKHGITKEVLKTYYAKKTVRAD
>NZ_HG939456.1|WP_000730410.1|1922211_1923600_+|HAMP-domain-containing-histidine-kinase
MKKKSLISNLILINSITLFLGFYLIYFSVNYVIKDYVHQMTRNSMQANFTILDSIYNNKKIPDENMVNQDSIFVWSYYAIFDQHYRMKYGTDNHKKESHDIIRYLTQKRLWQISKEKDGMFITIKKKTYYVMTKDYSGILVDGSIKKAPKAQSQLFHVINFSDITYTQHLITKINHFLIVILVLTYIPMLFIMRKTFTGIRESIQSVQTYISSLWKNQGNHQSSQKEIVFSDFDPLLLESQEMANRIYQAEESQRNFFQNASHELRTPLMSIQGYTEGVQEGIIDAELAHSVILQESKKMKQLVDDIILLSKLDSNLSDQKDEFSLNELLNSIIAYFKPLANKQKISITYRPDKHEKLLKGNEELIQRAINNILSNALRYAVSHIEISYTNQKLTISNDGPAISKEDLPYIFDRFYKGHGGQTGIGLAMTKEIIKQHHGNIIAESDSTSTTFTIYFNCHKIA
>NZ_HG939456.1|WP_001093377.1|1916581_1921297_+|S8-family-serine-peptidase
MNTKQRFSIRKYKLGAVSVLLGTLFFLGGITNVAADSVINKPSDIAVEQQVKDSPTSIANETPTNNTSSALASTAQDNLVTKANNNSPTETQPVTEPHSQATETFSPAANQPVESTQEVSKTPLTKQNLAVKPTPAISKETPQNIDSNKIITVPKVWNTGYKGEGTVVAIIDSGLDTNHDALQLNDSTKAKYQNEQQMNAAKAKAGINYGKWYNNKVIFGHNYVDVNTELKEVKSTSHGMHVTSIATANPSKKDTNELIYGVAPEAQVMFMRVFSDEKRGTGPALYVKAIEDAVKLGADSINLSLGGANGSLVNADDRLIKALEMARLAGVSVVIAAGNDGTFGSGASKPSALYPDYGLVGSPSTAREAISVASYNNTTLVNKVFNIIGLENNKNLNNGLAAYADPKVSDKTFEVGKQYDYVFVGKGNDNDYKDKTLNGKIALIERGDITFTKKVVNAINHGAVGAIIFNNKAGEANLTMSLDPEASAIPAIFTQKEFGDVLAKNNYKIVFNNIKNKQANPNAGVLSDFSSWGLTADGQLKPDLSAPGGSIYAAINDNEYDMMSGTSMASPHVAGATALVKQYLLKEHPELKKGDIERTVKYLLMSTAKAHLNKDTGAYTSPRQQGAGIIDVAAAVQTGLYLTGGENNYGSVTLGNIKDKISFDVTVHNINKVAKDLHYTTYLNTDQVKDGFVTLAPQQLGTFTGKTIRIEPGQTKTITIDIDVSKYHDMLKKVMPNGYFLEGYVRFTDPVDGGEVLSIPYVGFKGEFQNLEVLEKSIYKLVANKEKGFYFQPKQTNEVPGSEDYTALMTTSSEPIYSTDGTSPIQLKALGSYKSIDGKWILQLEQKGQPHLAISPNDDQNQDAVALKGVFLRNFNNLRAKVYRADDVNLQKPLWVSAPQAGDKNYYSGNTENPKSTFLYDTEWKGTTTDGIPLEDGKYKYVLTYYSDVPGSKPQQMVFDITLDRQAPTLTTATYDKDRRIFKARPAVEHGESGIFREQVFYLKKDKDGHYNSVLRQKGEDGILVEDNKVFIKQEKDGSFILPKEVNDFSHVYYTVEDYAGNLVSAKLEDLINIGNKNGLVNVKVFSPELNSNVDIDFSYSVKDDKGNVIKKQHHGKDLNLLKLPFGTYTFDLFLYDEERANLISPQSVTVTISEKDSLKDVLFKVNLLKKAALLVEFDKLLPKGATVQLVTKTNTVVDLPKATYSPTDYGKNIPVGDYRLNVTLPSGYSTLENLDDLLVSVKEGQVNLTKLTLINKAPLINALAEQTDIISQPVFYNAGTHLKNNYLANLEKAQTLIKNRVEQTSIDNAIAALRESRQALNGKETDTSLLAKAILAETEIKGNYQFVNASPLSQSTYINQVQLAKNLLQKPNVTQSEVDKALENLDIAKNQLNGHETDYSGLHHMIIKANVLKQTSSKYQNASQFAKENYNNLIKKAELLLSNRQATQAQVEELLNQIKATEQELDGRDRVSSAENYSQSLNDNDSLNTTPINPPNQPQALIFKKGMTKESEVAQKRVLGVTSQTDNQKIKTNKLPKTGESTPKITYTILLFSLSMLGLATIKLKSIKRE
>NZ_HG939456.1|WP_000497678.1|1936195_1936369_-|preprotein-translocase-subunit-SecE
MFVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLLAAGVMDLINRF
>NZ_HG939456.1|WP_000057521.1|1936404_1936557_-|50S-ribosomal-protein-L33
MAQKKASLACTECGSRNYSIGVSSTPKPTRLEVNKFCKYCKKYTIHKETR
>NZ_HG939456.1|WP_000764797.1|1936605_1938927_-|penicillin-binding-protein
MKLFDKFIDLFRVDEDNDEMTRKNEQETREETSNLDGEEVYDIDDITRPSKSQYQRGIRHQKENAKSRLEWLQKVDRYLPSPKNPIRRFWRRYRIGKLLFIALMAFILIFGSYLFYLSKTATVSDLQSALKTTTTIYDKNKEYAGKLSGQKGTYVELNAISDHLKNAVIATEDRTFYENNGVNFKRFFLAVATLGKFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVDAGQLTKSQAKEAASIGMKNRLADTYAGKINDYKYPSYFDAVVNEAIDTYGISEKDIVNNGYKIYTALDQNYQSGMQKTFDDTSLFPVSDYDGQSAQGASVALDPKTGGVRGLVGRVQSTKDAQFRSFNYATQSKRSPASTIKPLVVYSPAIASGWSIDKELPNKVQDFHGYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGLNMSSANKELGVALGGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGTFSNGTAINANVYGYTMAGKTGTTETDFNPNLSGDQWVVGYTPDVVISQWVGFKNTDKHHYLTDSSAGTASNIFSTQASYILPYTKGSSFTHIENAYFQNGIGSVYNAQDASNTTNQESRSIINDLKDSASKAAQDISRAVEDSNFQEKVKDAWNSLKDYFR
>NZ_HG939456.1|WP_000010475.1|1938970_1939855_+|RluA-family-pseudouridine-synthase
MSFSLKIRNPYGEHTVKELLEDYFLIPRKIRHFLRVKKHVLINNEFINWQTVVQENDTITLIFDDEDYPTKKIPLGRAELIDCLYEDEHLIIVNKPEGMKTHGNQPNEIALLNHVSAYSGQTCYVVHRLDMETSGAVLFAKNPFILPLINQRLERKEIWREYWALVEGKFSPKHQVLRDKIGRNRHDRRKRIIDSKNGQHAMTIIDVLKYIQNSSLIKCRLETGRTHQIRIHLSHHGHPLIGDPLYNPSSNNERLMLHAHRLTLSHPLTCETISVEAPSSTFEKVLNNYKKGVG
>NZ_HG939456.1|WP_000459240.1|1939879_1941520_-|hypothetical-protein
MFDFFKKKVVKVCLVIFGIVLVSLLSLGFFYFSKGQVLSRFVAARSRTSGQAFDNIKEYMVWSDTGESITNDEANYANFEPLSKSEARKLGQEIKEGNKNDSMYLKRVGSRLGIFPDYRIANKPMSLTLKTNVPKLDVLLNQKKVATSNSDHFSVTVERLPRTHYTASLEGTSDGKEIKLKKDYDGKNQTIDLSVAFKSFTVTSNLMDGNLYFGDNRIAKLKDGSYSVENYPVTDGSKAYIKKVFNDGEITSHKQKLISIADNQTIKLDVDGLLNEKEAGQKLITAFNQLILYVSTGQDPQTLGTVFEKGAENDFYKGLKESIKAKFVTDNRKASHFTIPNIVLNKMTQVGKESYQVNFAADYDFNYDKSTDPDKKTYGHIIQNLTGNFIMKKSGNSYLISNDGKKDITVAKETNKVKADPVSIFPENLVGSWKGEVEDGTVTMTFDKDGKVTQKKVYKDSKSKESNHSAKVTKLEDKGNGLYLYQYESGTDTTTFVTGGIGGLKVKYAYGIKIEGNKIIPVIWQTSSDGEFDYHKPLLSKPLTKQ
>NZ_HG939456.1|WP_000077169.1|1941689_1942901_-|phosphopentomutase
MSQFDRIHLVVLDSVGIGAAPDANDFVNAGVPDGASDTLGHISKTVGLAVPNMAKIGLGNIPRPQALKTVPAEENPSGYATKLQEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEDIITKIEDFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDIIPLEELYRICEYARSITMERPALLGRIIARPYVGDPGNFTRTANRHDYAVSPFEDTVLNKLDQAGIDTYAVGKINDIFNGSGINHDMGHNKSNSHGIDTLIKTMGLSEFEKGFSFTNLVDFDALYGHRRDPHGYRDCLHEFDERLPEIISAMRDKDLLLITADHGNDPTYAGTDHTREYIPLLAYSPSFTGNGLIPVGHFADISATVADNFGVDTAMIGESFLQDLV
>NZ_HG939456.1|WP_000453153.1|1942967_1943639_-|deoxyribose-phosphate-aldolase
MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPASYVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIKNGADEIDMVINLTDVKNGDFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFSTAGATFEDVEVMAKYVDEGVKIKAAGGISSLEDAEKFIALGASRLGTSRIIKIVKNQKVEEGTY
>NZ_HG939456.1|WP_001159691.1|1943668_1944871_-|NupC/NupG-family-nucleoside-CNT-transporter
MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIALILVRIPLGQQVVSVVSTGVTKVINCGQAGLNFVFGSLADSGTKTGFIFAIQTLGNIVFLSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYLGRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILFPQTEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLSGLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLDYRTALVATISLCGFANLSSLGICVSGIAVLCPEKRGTLARLVFRAMIGGIAVSMLSAFIVGIVTLF
>NZ_HG939456.1|WP_001182060.1|1944891_1945671_-|uridine-phosphorylase
MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNAVLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGIDLDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQCKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFLVVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ
>NZ_HG939456.1|WP_001125579.1|1945830_1946568_+|GntR-family-transcriptional-regulator
MPKNELNNKLNKLKHVQVYNKIFNMIQDGTYSPGMQLPSEPELAGQLNVSRATLRKSLALLQEDHLVKNIRGKGNFIRENSSNLSENGYENRQHPIKTCLTSKITEVELEFRVEVPAEAITASLKQETPVVVIADRWYHTDDGPLAYTLSFIPIELISDAEISLHDTKQLLNFIEEGIYHEGISSHSQSHLGYATSGNFSATKYTLSDHGQFILIQETIFNQEKILMCNKHYVPIEHFELSITSH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_HG939456_2	2.2\|1934589\|18\|NZ_HG939456\|CRT	1934589-1934606	18	NZ_HG939456.1	1934697-1934714	2	0.889

1. spacer 2.2|1934589|18|NZ_HG939456|CRT matches to position: 1934697-1934714, mismatch: 2, identity: 0.889

taacgtctgatttaactt	CRISPR spacer
taacttctggtttaactt	Protospacer
**** ****.********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_HG939456_1	1.3\|871818\|29\|NZ_HG939456\|CRISPRCasFinder	871818-871846	29	MH853356	Streptococcus phage LF2, partial genome	36956-36984	0	1.0
NZ_HG939456_1	1.5\|871950\|29\|NZ_HG939456\|CRISPRCasFinder	871950-871978	29	MK448971	Streptococcus phage Javan52, complete genome	25346-25374	0	1.0
NZ_HG939456_1	1.5\|871950\|29\|NZ_HG939456\|CRISPRCasFinder	871950-871978	29	MK448956	Streptococcus phage Javan48, complete genome	23665-23693	0	1.0
NZ_HG939456_1	1.8\|871818\|30\|NZ_HG939456\|CRT	871818-871847	30	MH853356	Streptococcus phage LF2, partial genome	36955-36984	0	1.0
NZ_HG939456_1	1.10\|871950\|30\|NZ_HG939456\|CRT	871950-871979	30	MK448971	Streptococcus phage Javan52, complete genome	25346-25375	0	1.0
NZ_HG939456_1	1.10\|871950\|30\|NZ_HG939456\|CRT	871950-871979	30	MK448956	Streptococcus phage Javan48, complete genome	23665-23694	0	1.0
NZ_HG939456_1	1.3\|871818\|29\|NZ_HG939456\|CRISPRCasFinder	871818-871846	29	MK448749	Streptococcus phage Javan39, complete genome	26022-26050	1	0.966
NZ_HG939456_1	1.8\|871818\|30\|NZ_HG939456\|CRT	871818-871847	30	MK448749	Streptococcus phage Javan39, complete genome	26022-26051	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448871	Streptococcus phage Javan196, complete genome	37399-37428	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448952	Streptococcus phage Javan472, complete genome	36830-36859	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448775	Streptococcus phage Javan489, complete genome	38943-38972	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448961	Streptococcus phage Javan494, complete genome	36338-36367	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448970	Streptococcus phage Javan516, complete genome	42552-42581	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448697	Streptococcus phage Javan185, complete genome	37399-37428	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448953	Streptococcus phage Javan474, complete genome	40664-40693	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448693	Streptococcus phage Javan177, complete genome	37399-37428	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448945	Streptococcus phage Javan454, complete genome	36499-36528	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448766	Streptococcus phage Javan465, complete genome	37195-37224	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448696	Streptococcus phage Javan183, complete genome	37399-37428	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448868	Streptococcus phage Javan188, complete genome	37400-37429	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448866	Streptococcus phage Javan184, complete genome	37399-37428	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448851	Streptococcus phage Javan14, complete genome	39043-39072	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448699	Streptococcus phage Javan189, complete genome	37399-37428	1	0.967
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448867	Streptococcus phage Javan186, complete genome	37399-37428	1	0.967
NZ_HG939456_1	1.3\|871818\|29\|NZ_HG939456\|CRISPRCasFinder	871818-871846	29	MK448694	Streptococcus phage Javan179, complete genome	25046-25074	2	0.931
NZ_HG939456_1	1.8\|871818\|30\|NZ_HG939456\|CRT	871818-871847	30	MK448694	Streptococcus phage Javan179, complete genome	25046-25075	2	0.933
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448796	Streptococcus phage Javan53, complete genome	44973-45002	2	0.933
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MK448956	Streptococcus phage Javan48, complete genome	38085-38114	2	0.933
NZ_HG939456_1	1.3\|871818\|29\|NZ_HG939456\|CRISPRCasFinder	871818-871846	29	JX409894	Streptococcus phage LYGO9, complete genome	22368-22396	3	0.897
NZ_HG939456_1	1.3\|871818\|29\|NZ_HG939456\|CRISPRCasFinder	871818-871846	29	JX409895	Streptococcus phage JX01, complete genome	34215-34243	3	0.897
NZ_HG939456_1	1.8\|871818\|30\|NZ_HG939456\|CRT	871818-871847	30	JX409894	Streptococcus phage LYGO9, complete genome	22367-22396	3	0.9
NZ_HG939456_1	1.8\|871818\|30\|NZ_HG939456\|CRT	871818-871847	30	JX409895	Streptococcus phage JX01, complete genome	34214-34243	3	0.9
NZ_HG939456_1	1.4\|871884\|29\|NZ_HG939456\|CRISPRCasFinder	871884-871912	29	MK448898	Streptococcus phage Javan284, complete genome	8520-8548	4	0.862
NZ_HG939456_1	1.4\|871884\|29\|NZ_HG939456\|CRISPRCasFinder	871884-871912	29	KY065502	Streptococcus phage IPP66, complete genome	7847-7875	4	0.862
NZ_HG939456_1	1.4\|871884\|29\|NZ_HG939456\|CRISPRCasFinder	871884-871912	29	MT900488	Streptococcus phage SA01, complete genome	8543-8571	4	0.862
NZ_HG939456_1	1.4\|871884\|29\|NZ_HG939456\|CRISPRCasFinder	871884-871912	29	AJ490330	Bacteriophage VO1 ORF1 and met gene for putative C5-methylase	736-764	4	0.862
NZ_HG939456_1	1.4\|871884\|29\|NZ_HG939456\|CRISPRCasFinder	871884-871912	29	KY065456	Streptococcus phage IPP15, complete genome	9104-9132	4	0.862
NZ_HG939456_1	1.4\|871884\|29\|NZ_HG939456\|CRISPRCasFinder	871884-871912	29	KT337358	Streptococcus phage phiARI0468-4, complete genome	28301-28329	4	0.862
NZ_HG939456_1	1.4\|871884\|29\|NZ_HG939456\|CRISPRCasFinder	871884-871912	29	NC_022791	Streptococcus phage phiBHN167 complete genome	23706-23734	4	0.862
NZ_HG939456_1	1.5\|871950\|29\|NZ_HG939456\|CRISPRCasFinder	871950-871978	29	MK448851	Streptococcus phage Javan14, complete genome	24320-24348	4	0.862
NZ_HG939456_1	1.9\|871884\|30\|NZ_HG939456\|CRT	871884-871913	30	KT337358	Streptococcus phage phiARI0468-4, complete genome	28300-28329	4	0.867
NZ_HG939456_1	1.9\|871884\|30\|NZ_HG939456\|CRT	871884-871913	30	NC_022791	Streptococcus phage phiBHN167 complete genome	23705-23734	4	0.867
NZ_HG939456_1	1.9\|871884\|30\|NZ_HG939456\|CRT	871884-871913	30	MK448898	Streptococcus phage Javan284, complete genome	8520-8549	4	0.867
NZ_HG939456_1	1.9\|871884\|30\|NZ_HG939456\|CRT	871884-871913	30	KY065502	Streptococcus phage IPP66, complete genome	7847-7876	4	0.867
NZ_HG939456_1	1.9\|871884\|30\|NZ_HG939456\|CRT	871884-871913	30	MT900488	Streptococcus phage SA01, complete genome	8543-8572	4	0.867
NZ_HG939456_1	1.9\|871884\|30\|NZ_HG939456\|CRT	871884-871913	30	AJ490330	Bacteriophage VO1 ORF1 and met gene for putative C5-methylase	736-765	4	0.867
NZ_HG939456_1	1.9\|871884\|30\|NZ_HG939456\|CRT	871884-871913	30	KY065456	Streptococcus phage IPP15, complete genome	9104-9133	4	0.867
NZ_HG939456_1	1.5\|871950\|29\|NZ_HG939456\|CRISPRCasFinder	871950-871978	29	NC_019691	Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence	26157-26185	5	0.828
NZ_HG939456_1	1.10\|871950\|30\|NZ_HG939456\|CRT	871950-871979	30	MK448851	Streptococcus phage Javan14, complete genome	24320-24349	5	0.833
NZ_HG939456_1	1.1\|871686\|29\|NZ_HG939456\|CRISPRCasFinder	871686-871714	29	MH595538	Vibrio phage BONAISHI, complete genome	251052-251080	6	0.793
NZ_HG939456_1	1.2\|871752\|29\|NZ_HG939456\|CRISPRCasFinder	871752-871780	29	NZ_CP026738	Bacillus megaterium strain YC4-R4 plasmid unnamed2	132907-132935	6	0.793
NZ_HG939456_1	1.2\|871752\|29\|NZ_HG939456\|CRISPRCasFinder	871752-871780	29	NC_014025	Bacillus megaterium QM B1551 plasmid pBM500, complete sequence	38203-38231	6	0.793
NZ_HG939456_1	1.10\|871950\|30\|NZ_HG939456\|CRT	871950-871979	30	NC_019691	Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence	26157-26186	6	0.8
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	NZ_CP014491	Escherichia coli strain G749 plasmid pG749_3, complete sequence	41416-41445	6	0.8
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	NC_041936	Escherichia phage ECD7, complete genome	82144-82173	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	CP020755	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence	425604-425633	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_018503	Bacillus thuringiensis HD-771 plasmid p07, complete sequence	5506-5535	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_017205	Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT72, complete sequence	24399-24428	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_017205	Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT72, complete sequence	24435-24464	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_017205	Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT72, complete sequence	24471-24500	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP010581	Bacillus thuringiensis serovar morrisoni strain BGSC 4AA1 plasmid pBMB68, complete sequence	28867-28896	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP010581	Bacillus thuringiensis serovar morrisoni strain BGSC 4AA1 plasmid pBMB68, complete sequence	28903-28932	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP010581	Bacillus thuringiensis serovar morrisoni strain BGSC 4AA1 plasmid pBMB68, complete sequence	28939-28968	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP015179	Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence	17263-17292	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP015179	Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence	17299-17328	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP015179	Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence	17335-17364	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP015179	Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence	17371-17400	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP015179	Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence	17407-17436	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	CP020758	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-19, complete sequence	54827-54856	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	CP020758	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-19, complete sequence	54863-54892	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	CP020758	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-19, complete sequence	54899-54928	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP010093	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB71, complete sequence	16332-16361	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP010093	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB71, complete sequence	16368-16397	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP010093	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB71, complete sequence	16404-16433	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP021065	Bacillus thuringiensis strain ATCC 10792 plasmid poh4, complete sequence	80302-80331	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP021065	Bacillus thuringiensis strain ATCC 10792 plasmid poh4, complete sequence	80338-80367	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP021065	Bacillus thuringiensis strain ATCC 10792 plasmid poh4, complete sequence	80374-80403	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_018488	Bacillus thuringiensis HD-771 plasmid p04, complete sequence	1454-1483	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_018488	Bacillus thuringiensis HD-771 plasmid p04, complete sequence	1490-1519	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_047926	Lactobacillus phage Semele, complete genome	8764-8793	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_018879	Bacillus thuringiensis Bt407 plasmid BTB_78p, complete sequence	37338-37367	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_018879	Bacillus thuringiensis Bt407 plasmid BTB_78p, complete sequence	37374-37403	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_018879	Bacillus thuringiensis Bt407 plasmid BTB_78p, complete sequence	37410-37439	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_020382	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-68, complete sequence	43074-43103	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_020382	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-68, complete sequence	43110-43139	6	0.8
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_020382	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-68, complete sequence	43146-43175	6	0.8
NZ_HG939456_1	1.3\|871818\|29\|NZ_HG939456\|CRISPRCasFinder	871818-871846	29	NZ_CP021745	Agarilytica rhodophyticola strain 017 plasmid pSU1, complete sequence	124622-124650	7	0.759
NZ_HG939456_1	1.3\|871818\|29\|NZ_HG939456\|CRISPRCasFinder	871818-871846	29	NZ_CP047439	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-2, complete sequence	37036-37064	7	0.759
NZ_HG939456_1	1.3\|871818\|29\|NZ_HG939456\|CRISPRCasFinder	871818-871846	29	NZ_CP047440	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-3, complete sequence	62197-62225	7	0.759
NZ_HG939456_1	1.6\|871686\|30\|NZ_HG939456\|CRT	871686-871715	30	NC_015937	Thermus phage TMA, complete genome	108316-108345	7	0.767
NZ_HG939456_1	1.6\|871686\|30\|NZ_HG939456\|CRT	871686-871715	30	MH595538	Vibrio phage BONAISHI, complete genome	251052-251081	7	0.767
NZ_HG939456_1	1.6\|871686\|30\|NZ_HG939456\|CRT	871686-871715	30	AP011617	Thermus phage TMA DNA, complete genome	108316-108345	7	0.767
NZ_HG939456_1	1.7\|871752\|30\|NZ_HG939456\|CRT	871752-871781	30	NZ_CP026738	Bacillus megaterium strain YC4-R4 plasmid unnamed2	132906-132935	7	0.767
NZ_HG939456_1	1.7\|871752\|30\|NZ_HG939456\|CRT	871752-871781	30	NC_014025	Bacillus megaterium QM B1551 plasmid pBM500, complete sequence	38202-38231	7	0.767
NZ_HG939456_1	1.8\|871818\|30\|NZ_HG939456\|CRT	871818-871847	30	NZ_CP047439	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-2, complete sequence	37036-37065	7	0.767
NZ_HG939456_1	1.8\|871818\|30\|NZ_HG939456\|CRT	871818-871847	30	NZ_CP047440	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-3, complete sequence	62197-62226	7	0.767
NZ_HG939456_1	1.10\|871950\|30\|NZ_HG939456\|CRT	871950-871979	30	MK448821	Streptococcus phage Javan623, complete genome	20349-20378	7	0.767
NZ_HG939456_1	1.10\|871950\|30\|NZ_HG939456\|CRT	871950-871979	30	MK448822	Streptococcus phage Javan629, complete genome	23253-23282	7	0.767
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	135471-135500	7	0.767
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	CP015514	Vibrio vulnificus strain FORC_036 plasmid unnamed, complete sequence	858564-858593	7	0.767
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	MG945249	UNVERIFIED: Microviridae sp. isolate 2447-1602, partial genome	2309-2338	7	0.767
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_CP015179	Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence	17119-17148	7	0.767
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NZ_AP014682	Lactobacillus hokkaidonensis JCM 18461 strain LOOC260 plasmid pLOOC260-2, complete sequence	29107-29136	7	0.767
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	NC_018488	Bacillus thuringiensis HD-771 plasmid p04, complete sequence	1418-1447	7	0.767
NZ_HG939456_1	1.8\|871818\|30\|NZ_HG939456\|CRT	871818-871847	30	NZ_CP021745	Agarilytica rhodophyticola strain 017 plasmid pSU1, complete sequence	124621-124650	8	0.733
NZ_HG939456_1	1.11\|872016\|30\|NZ_HG939456\|CRT	872016-872045	30	NC_022883	Enterococcus mundtii QU 25 plasmid pQY082, complete sequence	57911-57940	8	0.733
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	MH707430	Bacillus phage BSP7, complete genome	30317-30346	8	0.733
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	MN694344	Marine virus AFVG_250M1167, complete genome	33263-33292	8	0.733
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	MN693686	Marine virus AFVG_250M1168, complete genome	11193-11222	8	0.733
NZ_HG939456_2	2.1\|1934541\|30\|NZ_HG939456\|CRT	1934541-1934570	30	CP017837	Proteobacteria phage MWH-Nonnen-W8red 2 genome	25051-25080	8	0.733
NZ_HG939456_2	2.3\|1934625\|30\|NZ_HG939456\|CRT	1934625-1934654	30	MN855875	Bacteriophage sp. isolate 328, complete genome	1404-1433	8	0.733

1. spacer 1.3|871818|29|NZ_HG939456|CRISPRCasFinder matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 0, identity: 1.0

tgctaaaaggtaaatttaacattccaggt	CRISPR spacer
tgctaaaaggtaaatttaacattccaggt	Protospacer
*****************************

2. spacer 1.5|871950|29|NZ_HG939456|CRISPRCasFinder matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 0, identity: 1.0

gataaaaagtgggagctgaattaaaaggc	CRISPR spacer
gataaaaagtgggagctgaattaaaaggc	Protospacer
*****************************

3. spacer 1.5|871950|29|NZ_HG939456|CRISPRCasFinder matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

gataaaaagtgggagctgaattaaaaggc	CRISPR spacer
gataaaaagtgggagctgaattaaaaggc	Protospacer
*****************************

4. spacer 1.8|871818|30|NZ_HG939456|CRT matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 0, identity: 1.0

tgctaaaaggtaaatttaacattccaggta	CRISPR spacer
tgctaaaaggtaaatttaacattccaggta	Protospacer
******************************

5. spacer 1.10|871950|30|NZ_HG939456|CRT matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 0, identity: 1.0

gataaaaagtgggagctgaattaaaaggca	CRISPR spacer
gataaaaagtgggagctgaattaaaaggca	Protospacer
******************************

6. spacer 1.10|871950|30|NZ_HG939456|CRT matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

gataaaaagtgggagctgaattaaaaggca	CRISPR spacer
gataaaaagtgggagctgaattaaaaggca	Protospacer
******************************

7. spacer 1.3|871818|29|NZ_HG939456|CRISPRCasFinder matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 1, identity: 0.966

tgctaaaaggtaaatttaacattccaggt	CRISPR spacer
tgctaaaaggtaaatttaacattccaggc	Protospacer
****************************.

8. spacer 1.8|871818|30|NZ_HG939456|CRT matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 1, identity: 0.967

tgctaaaaggtaaatttaacattccaggta	CRISPR spacer
tgctaaaaggtaaatttaacattccaggca	Protospacer
****************************.*

9. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448871 (Streptococcus phage Javan196, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

10. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448952 (Streptococcus phage Javan472, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

11. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

12. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448961 (Streptococcus phage Javan494, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

13. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

14. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448697 (Streptococcus phage Javan185, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

15. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448953 (Streptococcus phage Javan474, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

16. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448693 (Streptococcus phage Javan177, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

17. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448945 (Streptococcus phage Javan454, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

18. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448766 (Streptococcus phage Javan465, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

19. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448696 (Streptococcus phage Javan183, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

20. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448868 (Streptococcus phage Javan188, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

21. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448866 (Streptococcus phage Javan184, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

22. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

23. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448699 (Streptococcus phage Javan189, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

24. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448867 (Streptococcus phage Javan186, complete genome) position: , mismatch: 1, identity: 0.967

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctgatatgt	Protospacer
**********.*******************

25. spacer 1.3|871818|29|NZ_HG939456|CRISPRCasFinder matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 2, identity: 0.931

tgctaaaaggtaaatttaacattccaggt	CRISPR spacer
tgctaaaaggtaagtttaacattccgggt	Protospacer
*************.***********.***

26. spacer 1.8|871818|30|NZ_HG939456|CRT matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 2, identity: 0.933

tgctaaaaggtaaatttaacattccaggta	CRISPR spacer
tgctaaaaggtaagtttaacattccgggta	Protospacer
*************.***********.****

27. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 2, identity: 0.933

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctggtatgt	Protospacer
**********.*************.*****

28. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 2, identity: 0.933

atttgaacgatttttatattcctgatatgt	CRISPR spacer
atttgaacgacttttatattcctggtatgt	Protospacer
**********.*************.*****

29. spacer 1.3|871818|29|NZ_HG939456|CRISPRCasFinder matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 3, identity: 0.897

tgctaaaaggtaaatttaacattccaggt	CRISPR spacer
tgttaaaaggtaaatttaacattcctggc	Protospacer
**.********************** **.

30. spacer 1.3|871818|29|NZ_HG939456|CRISPRCasFinder matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 3, identity: 0.897

tgctaaaaggtaaatttaacattccaggt	CRISPR spacer
tgttaaaaggtaaatttaacattcctggc	Protospacer
**.********************** **.

31. spacer 1.8|871818|30|NZ_HG939456|CRT matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 3, identity: 0.9

tgctaaaaggtaaatttaacattccaggta	CRISPR spacer
tgttaaaaggtaaatttaacattcctggca	Protospacer
**.********************** **.*

32. spacer 1.8|871818|30|NZ_HG939456|CRT matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 3, identity: 0.9

tgctaaaaggtaaatttaacattccaggta	CRISPR spacer
tgttaaaaggtaaatttaacattcctggca	Protospacer
**.********************** **.*

33. spacer 1.4|871884|29|NZ_HG939456|CRISPRCasFinder matches to MK448898 (Streptococcus phage Javan284, complete genome) position: , mismatch: 4, identity: 0.862

tatttgatagcggtaacgggtcatataca	CRISPR spacer
ttttcgatagcggtaacggttcatatact	Protospacer
* **.************** ********

34. spacer 1.4|871884|29|NZ_HG939456|CRISPRCasFinder matches to KY065502 (Streptococcus phage IPP66, complete genome) position: , mismatch: 4, identity: 0.862

tatttgatagcggtaacgggtcatataca	CRISPR spacer
tgtttgatagtggtaacggctcatatact	Protospacer
*.********.******** ********

35. spacer 1.4|871884|29|NZ_HG939456|CRISPRCasFinder matches to MT900488 (Streptococcus phage SA01, complete genome) position: , mismatch: 4, identity: 0.862

tatttgatagcggtaacgggtcatataca	CRISPR spacer
tgtttgatagtggtaacggctcatatact	Protospacer
*.********.******** ********

36. spacer 1.4|871884|29|NZ_HG939456|CRISPRCasFinder matches to AJ490330 (Bacteriophage VO1 ORF1 and met gene for putative C5-methylase) position: , mismatch: 4, identity: 0.862

tatttgatagcggtaacgggtcatataca	CRISPR spacer
tgtttgatagtggtaacggctcatatact	Protospacer
*.********.******** ********

37. spacer 1.4|871884|29|NZ_HG939456|CRISPRCasFinder matches to KY065456 (Streptococcus phage IPP15, complete genome) position: , mismatch: 4, identity: 0.862

tatttgatagcggtaacgggtcatataca	CRISPR spacer
tgtttgatagtggtaacggctcatatact	Protospacer
*.********.******** ********

38. spacer 1.4|871884|29|NZ_HG939456|CRISPRCasFinder matches to KT337358 (Streptococcus phage phiARI0468-4, complete genome) position: , mismatch: 4, identity: 0.862

tatttgatagcggtaacgggtcatataca	CRISPR spacer
tgtttgatagtggtaacggctcatatact	Protospacer
*.********.******** ********

39. spacer 1.4|871884|29|NZ_HG939456|CRISPRCasFinder matches to NC_022791 (Streptococcus phage phiBHN167 complete genome) position: , mismatch: 4, identity: 0.862

tatttgatagcggtaacgggtcatataca	CRISPR spacer
tgtttgatagtggtaacggctcatatact	Protospacer
*.********.******** ********

40. spacer 1.5|871950|29|NZ_HG939456|CRISPRCasFinder matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 4, identity: 0.862

gataaaaagtgggagctgaattaaaaggc	CRISPR spacer
gttaaaaaatgggtgctgaattaaaagga	Protospacer
* ******.**** **************

41. spacer 1.9|871884|30|NZ_HG939456|CRT matches to KT337358 (Streptococcus phage phiARI0468-4, complete genome) position: , mismatch: 4, identity: 0.867

tatttgatagcggtaacgggtcatatacaa	CRISPR spacer
tgtttgatagtggtaacggctcatatacta	Protospacer
*.********.******** ******** *

42. spacer 1.9|871884|30|NZ_HG939456|CRT matches to NC_022791 (Streptococcus phage phiBHN167 complete genome) position: , mismatch: 4, identity: 0.867

tatttgatagcggtaacgggtcatatacaa	CRISPR spacer
tgtttgatagtggtaacggctcatatacta	Protospacer
*.********.******** ******** *

43. spacer 1.9|871884|30|NZ_HG939456|CRT matches to MK448898 (Streptococcus phage Javan284, complete genome) position: , mismatch: 4, identity: 0.867

tatttgatagcggtaacgggtcatatacaa	CRISPR spacer
ttttcgatagcggtaacggttcatatacta	Protospacer
* **.************** ******** *

44. spacer 1.9|871884|30|NZ_HG939456|CRT matches to KY065502 (Streptococcus phage IPP66, complete genome) position: , mismatch: 4, identity: 0.867

tatttgatagcggtaacgggtcatatacaa	CRISPR spacer
tgtttgatagtggtaacggctcatatacta	Protospacer
*.********.******** ******** *

45. spacer 1.9|871884|30|NZ_HG939456|CRT matches to MT900488 (Streptococcus phage SA01, complete genome) position: , mismatch: 4, identity: 0.867

tatttgatagcggtaacgggtcatatacaa	CRISPR spacer
tgtttgatagtggtaacggctcatatacta	Protospacer
*.********.******** ******** *

46. spacer 1.9|871884|30|NZ_HG939456|CRT matches to AJ490330 (Bacteriophage VO1 ORF1 and met gene for putative C5-methylase) position: , mismatch: 4, identity: 0.867

tatttgatagcggtaacgggtcatatacaa	CRISPR spacer
tgtttgatagtggtaacggctcatatacta	Protospacer
*.********.******** ******** *

47. spacer 1.9|871884|30|NZ_HG939456|CRT matches to KY065456 (Streptococcus phage IPP15, complete genome) position: , mismatch: 4, identity: 0.867

tatttgatagcggtaacgggtcatatacaa	CRISPR spacer
tgtttgatagtggtaacggctcatatacta	Protospacer
*.********.******** ******** *

48. spacer 1.5|871950|29|NZ_HG939456|CRISPRCasFinder matches to NC_019691 (Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence) position: , mismatch: 5, identity: 0.828

gataaaaagtgggagctgaattaaaaggc	CRISPR spacer
tagataaagtggaagctgaattaaaagga	Protospacer
 * * *******.***************

49. spacer 1.10|871950|30|NZ_HG939456|CRT matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 5, identity: 0.833

gataaaaagtgggagctgaattaaaaggca	CRISPR spacer
gttaaaaaatgggtgctgaattaaaaggag	Protospacer
* ******.**** ************** .

50. spacer 1.1|871686|29|NZ_HG939456|CRISPRCasFinder matches to MH595538 (Vibrio phage BONAISHI, complete genome) position: , mismatch: 6, identity: 0.793

atttgacaaacattgaacttaaaagaaac	CRISPR spacer
ttaaggcaaacattgaacataaaggaaac	Protospacer
 *  *.************ ****.*****

51. spacer 1.2|871752|29|NZ_HG939456|CRISPRCasFinder matches to NZ_CP026738 (Bacillus megaterium strain YC4-R4 plasmid unnamed2) position: , mismatch: 6, identity: 0.793

ctgttcataaagagcaactagtggcaaca	CRISPR spacer
ttgttcataaagagcaactagtcagagcg	Protospacer
.********************* . *.*.

52. spacer 1.2|871752|29|NZ_HG939456|CRISPRCasFinder matches to NC_014025 (Bacillus megaterium QM B1551 plasmid pBM500, complete sequence) position: , mismatch: 6, identity: 0.793

ctgttcataaagagcaactagtggcaaca	CRISPR spacer
ttgttcataaagagcaactagtcagagcg	Protospacer
.********************* . *.*.

53. spacer 1.10|871950|30|NZ_HG939456|CRT matches to NC_019691 (Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence) position: , mismatch: 6, identity: 0.8

gataaaaagtgggagctgaattaaaaggca	CRISPR spacer
tagataaagtggaagctgaattaaaaggag	Protospacer
 * * *******.*************** .

54. spacer 1.11|872016|30|NZ_HG939456|CRT matches to NZ_CP014491 (Escherichia coli strain G749 plasmid pG749_3, complete sequence) position: , mismatch: 6, identity: 0.8

atttgaacgatttttatattcctgatatgt	CRISPR spacer
ctctttatgatttttatattcctgatatgc	Protospacer
 *.*  *.*********************.

55. spacer 1.11|872016|30|NZ_HG939456|CRT matches to NC_041936 (Escherichia phage ECD7, complete genome) position: , mismatch: 6, identity: 0.8

-atttgaacgatttttatattcctgatatgt	CRISPR spacer
caggtg-acaattttaatattcctgatatgc	Protospacer
 *  ** **.***** **************.

56. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to CP020755 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttttcctctggtttgtttc	Protospacer
* ***********  *********** .*.

57. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_018503 (Bacillus thuringiensis HD-771 plasmid p07, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tagtttctggtttagtctctggtttagtct	Protospacer
**..***********.*********.*..*

58. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_017205 (Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT72, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

59. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_017205 (Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT72, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

60. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_017205 (Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT72, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

61. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP010581 (Bacillus thuringiensis serovar morrisoni strain BGSC 4AA1 plasmid pBMB68, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

62. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP010581 (Bacillus thuringiensis serovar morrisoni strain BGSC 4AA1 plasmid pBMB68, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

63. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP010581 (Bacillus thuringiensis serovar morrisoni strain BGSC 4AA1 plasmid pBMB68, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

64. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP015179 (Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

65. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP015179 (Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

66. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP015179 (Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

67. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP015179 (Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

68. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP015179 (Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
ttacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

69. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to CP020758 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-19, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

70. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to CP020758 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-19, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

71. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to CP020758 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-19, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

72. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP010093 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB71, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

73. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP010093 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB71, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

74. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP010093 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB71, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

75. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP021065 (Bacillus thuringiensis strain ATCC 10792 plasmid poh4, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

76. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP021065 (Bacillus thuringiensis strain ATCC 10792 plasmid poh4, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

77. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP021065 (Bacillus thuringiensis strain ATCC 10792 plasmid poh4, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

78. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_018488 (Bacillus thuringiensis HD-771 plasmid p04, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

79. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_018488 (Bacillus thuringiensis HD-771 plasmid p04, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

80. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_047926 (Lactobacillus phage Semele, complete genome) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
gaacttctggcttagcttctggttcagttt	Protospacer
 *********.*****.*******..*.**

81. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_018879 (Bacillus thuringiensis Bt407 plasmid BTB_78p, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

82. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_018879 (Bacillus thuringiensis Bt407 plasmid BTB_78p, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

83. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_018879 (Bacillus thuringiensis Bt407 plasmid BTB_78p, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

84. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_020382 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-68, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

85. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_020382 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-68, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

86. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_020382 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-68, complete sequence) position: , mismatch: 6, identity: 0.8

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggtttttcct	Protospacer
* *************.*** *****  *.*

87. spacer 1.3|871818|29|NZ_HG939456|CRISPRCasFinder matches to NZ_CP021745 (Agarilytica rhodophyticola strain 017 plasmid pSU1, complete sequence) position: , mismatch: 7, identity: 0.759

tgctaaaaggtaaatttaacattccaggt	CRISPR spacer
tgctataaggtaaatttaaccttctccaa	Protospacer
***** ************** ***.  .

88. spacer 1.3|871818|29|NZ_HG939456|CRISPRCasFinder matches to NZ_CP047439 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-2, complete sequence) position: , mismatch: 7, identity: 0.759

tgctaaaaggtaaatttaacattccaggt	CRISPR spacer
aagtaaaagataaattaaacattccaaat	Protospacer
 . ******.****** *********..*

89. spacer 1.3|871818|29|NZ_HG939456|CRISPRCasFinder matches to NZ_CP047440 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-3, complete sequence) position: , mismatch: 7, identity: 0.759

tgctaaaaggtaaatttaacattccaggt	CRISPR spacer
aagtaaaagataaattaaacattccaaat	Protospacer
 . ******.****** *********..*

90. spacer 1.6|871686|30|NZ_HG939456|CRT matches to NC_015937 (Thermus phage TMA, complete genome) position: , mismatch: 7, identity: 0.767

----atttgacaaacattgaacttaaaagaaact	CRISPR spacer
cagaat----aaaacattaaactcaaaagaaact	Protospacer
    **     *******.****.**********

91. spacer 1.6|871686|30|NZ_HG939456|CRT matches to MH595538 (Vibrio phage BONAISHI, complete genome) position: , mismatch: 7, identity: 0.767

atttgacaaacattgaacttaaaagaaact	CRISPR spacer
ttaaggcaaacattgaacataaaggaaaca	Protospacer
 *  *.************ ****.*****

92. spacer 1.6|871686|30|NZ_HG939456|CRT matches to AP011617 (Thermus phage TMA DNA, complete genome) position: , mismatch: 7, identity: 0.767

----atttgacaaacattgaacttaaaagaaact	CRISPR spacer
cagaat----aaaacattaaactcaaaagaaact	Protospacer
    **     *******.****.**********

93. spacer 1.7|871752|30|NZ_HG939456|CRT matches to NZ_CP026738 (Bacillus megaterium strain YC4-R4 plasmid unnamed2) position: , mismatch: 7, identity: 0.767

ctgttcataaagagcaactagtggcaacat	CRISPR spacer
ttgttcataaagagcaactagtcagagcga	Protospacer
.********************* . *.*.

94. spacer 1.7|871752|30|NZ_HG939456|CRT matches to NC_014025 (Bacillus megaterium QM B1551 plasmid pBM500, complete sequence) position: , mismatch: 7, identity: 0.767

ctgttcataaagagcaactagtggcaacat	CRISPR spacer
ttgttcataaagagcaactagtcagagcga	Protospacer
.********************* . *.*.

95. spacer 1.8|871818|30|NZ_HG939456|CRT matches to NZ_CP047439 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-2, complete sequence) position: , mismatch: 7, identity: 0.767

tgctaaaaggtaaatttaacattccaggta	CRISPR spacer
aagtaaaagataaattaaacattccaaata	Protospacer
 . ******.****** *********..**

96. spacer 1.8|871818|30|NZ_HG939456|CRT matches to NZ_CP047440 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-3, complete sequence) position: , mismatch: 7, identity: 0.767

tgctaaaaggtaaatttaacattccaggta	CRISPR spacer
aagtaaaagataaattaaacattccaaata	Protospacer
 . ******.****** *********..**

97. spacer 1.10|871950|30|NZ_HG939456|CRT matches to MK448821 (Streptococcus phage Javan623, complete genome) position: , mismatch: 7, identity: 0.767

gataaaaagtgggagctgaattaaaaggca	CRISPR spacer
tagttagtatgggagctgaattaaaaggca	Protospacer
 *   *. .*********************

98. spacer 1.10|871950|30|NZ_HG939456|CRT matches to MK448822 (Streptococcus phage Javan629, complete genome) position: , mismatch: 7, identity: 0.767

gataaaaagtgggagctgaattaaaaggca	CRISPR spacer
tagttagtatgggagctgaattaaaaggca	Protospacer
 *   *. .*********************

99. spacer 1.11|872016|30|NZ_HG939456|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 7, identity: 0.767

atttgaacgatttttatattcctgatatgt	CRISPR spacer
ttgggaaaaatttttatattcctgatattc	Protospacer
 *  *** .******************* .

100. spacer 1.11|872016|30|NZ_HG939456|CRT matches to CP015514 (Vibrio vulnificus strain FORC_036 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

atttgaacgatttttatattcctgatatgt	CRISPR spacer
aaggtaacgatatttatattcctgatctgg	Protospacer
*    ****** ************** **

101. spacer 1.11|872016|30|NZ_HG939456|CRT matches to MG945249 (UNVERIFIED: Microviridae sp. isolate 2447-1602, partial genome) position: , mismatch: 7, identity: 0.767

atttgaacgatttttatattcctgatatgt	CRISPR spacer
ttgctcaagatttttatattcttgatatgt	Protospacer
 * .  * *************.********

102. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_CP015179 (Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence) position: , mismatch: 7, identity: 0.767

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggttttttct	Protospacer
* *************.*** *****  ..*

103. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NZ_AP014682 (Lactobacillus hokkaidonensis JCM 18461 strain LOOC260 plasmid pLOOC260-2, complete sequence) position: , mismatch: 7, identity: 0.767

taacttctggtttagcctctggtttggctt	CRISPR spacer
ttcttactggtttagccactggtttagcta	Protospacer
*  .* *********** *******.***

104. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to NC_018488 (Bacillus thuringiensis HD-771 plasmid p04, complete sequence) position: , mismatch: 7, identity: 0.767

taacttctggtttagcctctggtttggctt	CRISPR spacer
tcacttctggtttagtctcaggttttttct	Protospacer
* *************.*** *****  ..*

105. spacer 1.8|871818|30|NZ_HG939456|CRT matches to NZ_CP021745 (Agarilytica rhodophyticola strain 017 plasmid pSU1, complete sequence) position: , mismatch: 8, identity: 0.733

tgctaaaaggtaaatttaacattccaggta	CRISPR spacer
tgctataaggtaaatttaaccttctccaag	Protospacer
***** ************** ***.  . .

106. spacer 1.11|872016|30|NZ_HG939456|CRT matches to NC_022883 (Enterococcus mundtii QU 25 plasmid pQY082, complete sequence) position: , mismatch: 8, identity: 0.733

atttgaacgatttttatattcctgatatgt	CRISPR spacer
tattgaatgatttctatattcctgaagggg	Protospacer
  *****.*****.*********** . *

107. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to MH707430 (Bacillus phage BSP7, complete genome) position: , mismatch: 8, identity: 0.733

taacttctggtttagcctctggtttggctt	CRISPR spacer
cttcttcttgtttagcctctggtttagggc	Protospacer
.  ***** ****************.*  .

108. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to MN694344 (Marine virus AFVG_250M1167, complete genome) position: , mismatch: 8, identity: 0.733

taacttctggtttagcctctggtttggctt	CRISPR spacer
caactgctggtttagactctggtttacacc	Protospacer
.**** ********* *********.  ..

109. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to MN693686 (Marine virus AFVG_250M1168, complete genome) position: , mismatch: 8, identity: 0.733

taacttctggtttagcctctggtttggctt	CRISPR spacer
caactgctggtttagactctggtttacacc	Protospacer
.**** ********* *********.  ..

110. spacer 2.1|1934541|30|NZ_HG939456|CRT matches to CP017837 (Proteobacteria phage MWH-Nonnen-W8red 2 genome) position: , mismatch: 8, identity: 0.733

taacttctggtttagcctctggtttggctt	CRISPR spacer
ctgtttctggtttaggctctggtttaactg	Protospacer
. ..*********** *********..**

111. spacer 2.3|1934625|30|NZ_HG939456|CRT matches to MN855875 (Bacteriophage sp. isolate 328, complete genome) position: , mismatch: 8, identity: 0.733

tggcctctggcttaacgtctggtttaactt	CRISPR spacer
tggcctctggctcaacgtctgcgccatccg	Protospacer
************.********  ..* *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36644 : 48708

Microbacterium_phage(14.29%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001042246.1\|36644_40370_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	4.3e-38	26.0
WP_000220678.1\|40603_42058_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.4e-53	32.5
WP_001291333.1\|42085_43108_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	2.0e-62	42.7
WP_000685108.1\|43274_43823_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.0e-25	35.6
WP_000780023.1\|43845_44598_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000166553.1\|44617_46165_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.5e-77	48.9
WP_001045908.1\|46357_47257_+	peptidoglycan DD-metalloendopeptidase family protein	A0A221J6U0	Arthrobacter_phage	4.1e-19	45.9
WP_000783413.1\|47403_48708_+	LysM peptidoglycan-binding domain-containing protein	A0A2D1GNZ3	Streptomyces_phage	1.7e-05	40.5

DBSCAN-SWA_2

504633 : 567376

Streptococcus_phage(33.33%)

integrase,transposase,protease,tRNA

attL 530954:530971|attR 578916:578933

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000882544.1\|504633_506895_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A2C9CYX3	Yersinia_phage	5.7e-126	39.4
WP_000443582.1\|507192_507423_+	DUF1797 family protein	NA	NA	NA	NA
WP_001011647.1\|507563_508256_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000230129.1\|508248_508983_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-35	41.8
WP_001106849.1\|509269_510964_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	7.7e-128	43.3
WP_000137498.1\|511102_511957_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	1.5e-39	40.2
WP_000634982.1\|511953_512790_+	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_001286946.1\|512915_514256_+	exodeoxyribonuclease VII large subunit	L7RDW5	Acanthamoeba_polyphaga_moumouvirus	2.0e-38	32.0
WP_001280898.1\|514233_514449_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_000256277.1\|514448_515321_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_001041038.1\|515313_516141_+	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_000747940.1\|516127_516601_+	ArgR family transcriptional regulator	NA	NA	NA	NA
WP_000923611.1\|516612_518271_+	DNA repair protein RecN	NA	NA	NA	NA
WP_000034835.1\|518383_519220_+	DegV family protein	NA	NA	NA	NA
WP_001035227.1\|519212_520052_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_000806954.1\|520026_520629_+	YpmS family protein	NA	NA	NA	NA
WP_001284634.1\|520731_521007_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	1.2e-25	71.9
WP_001290370.1\|521203_521401_+	hypothetical protein	NA	NA	NA	NA
WP_000254068.1\|521444_522377_-	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	1.9e-64	43.4
WP_001185383.1\|522564_523800_-	aminoacyltransferase	NA	NA	NA	NA
WP_000285517.1\|523818_525030_-	aminoacyltransferase	NA	NA	NA	NA
WP_000527082.1\|525042_526278_-	aminoacyltransferase	NA	NA	NA	NA
WP_000200660.1\|526262_527075_-	sugar-phosphatase	NA	NA	NA	NA
WP_001003542.1\|527146_528463_-	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	8.1e-24	29.6
WP_001209457.1\|528526_528925_+	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_000910750.1\|529268_531953_+	calcium-translocating P-type ATPase, PMCA-type	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	1.1e-70	29.3
530954:530971	attL	NA	NA	NA	NA
WP_000064641.1\|533009_534941_+	fructose-bisphosphatase class III	NA	NA	NA	NA
WP_000351633.1\|535030_536155_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_011324939.1\|536223_537321_+	peptide chain release factor 2	NA	NA	NA	NA
WP_001173889.1\|537340_538033_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	1.3e-28	35.1
WP_000236202.1\|538016_538946_+	ABC transporter permease	NA	NA	NA	NA
WP_165694720.1\|539019_540364_+\|transposase	IS3-like element IS861 family transposase	A0A1B1P773	Bacillus_phage	2.8e-64	50.0
WP_001022577.1\|540434_541145_-	thioesterase	NA	NA	NA	NA
WP_001115859.1\|541141_541840_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.5e-82	64.9
WP_000048142.1\|542007_542772_+	(S)-acetoin forming diacetyl reductase	V5L4T3	Hirudovirus	9.8e-06	31.8
WP_000458617.1\|542879_545387_+	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	1.4e-218	50.5
WP_000221828.1\|545472_546666_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000038473.1\|546686_548033_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	3.7e-56	31.2
WP_000167485.1\|548072_548630_-	ECF transporter S component	NA	NA	NA	NA
WP_001031103.1\|548626_549610_-	nucleoside hydrolase	NA	NA	NA	NA
WP_000965178.1\|549855_550269_-	OsmC family protein	NA	NA	NA	NA
WP_001278845.1\|550422_551313_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	7.4e-05	28.1
WP_001231102.1\|551309_552284_+	YvcK family protein	A1IMD5	Streptococcus_phage	9.8e-144	78.8
WP_000011316.1\|552280_553192_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.4e-107	65.7
WP_000752455.1\|553206_554604_+	C69 family dipeptidase	NA	NA	NA	NA
WP_001227397.1\|554745_556266_+	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_000710757.1\|556378_556639_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_000583233.1\|556747_557683_-	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_000189636.1\|557949_558972_+	adenosine deaminase	NA	NA	NA	NA
WP_001162136.1\|559030_559474_+	flavodoxin	NA	NA	NA	NA
WP_000418127.1\|559550_559826_+	chorismate mutase	NA	NA	NA	NA
WP_000595706.1\|559818_561015_+	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	3.6e-103	54.5
WP_001068667.1\|561598_561946_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_071659971.1\|562090_562705_-\|integrase	site-specific integrase	F8HGP4	Streptococcus_phage	9.2e-55	60.7
WP_001872365.1\|562707_562974_-	hypothetical protein	Q77YW7	Streptococcus_phage	9.2e-20	65.2
WP_000640620.1\|562973_563378_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001122304.1\|563539_563740_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_001865698.1\|563761_564022_+\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	3.4e-11	43.0
WP_001867107.1\|564147_564357_+\|transposase	transposase	A0A0C5AEA5	Paenibacillus_phage	1.4e-15	55.4
WP_000508795.1\|564529_564691_-	NINE protein	NA	NA	NA	NA
WP_000594360.1\|565432_566710_+	ABC transporter permease	NA	NA	NA	NA
WP_000353149.1\|566719_567376_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-22	31.8
578916:578933	attR	NA	NA	NA	NA

DBSCAN-SWA_3

916025 : 937891

Streptococcus_phage(88.89%)

integrase

attL 930048:930062|attR 945684:945698

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000421280.1\|916025_916340_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	7.0e-43	76.7
WP_001234189.1\|916360_916738_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	5.6e-47	77.2
WP_000185760.1\|916747_917521_+	hypothetical protein	NA	NA	NA	NA
WP_001130247.1\|917542_918946_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	2.3e-178	67.2
WP_000426691.1\|919127_920312_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	1.0e-158	67.6
WP_000055367.1\|920308_920581_+	hypothetical protein	NA	NA	NA	NA
WP_001009054.1\|920577_920799_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	3.1e-29	93.2
WP_000678782.1\|920840_921620_+	abortive infection family protein	NA	NA	NA	NA
WP_000421245.1\|921681_922182_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	5.4e-53	61.1
WP_000234705.1\|922253_923279_+	hypothetical protein	NA	NA	NA	NA
WP_000723886.1\|923349_923745_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	1.7e-49	75.0
WP_000941001.1\|923728_926182_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	79.1
WP_000192390.1\|926178_928206_+	hypothetical protein	A0A1S5SF30	Streptococcus_phage	1.8e-195	65.7
WP_000768374.1\|928202_929225_+	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	1.4e-132	75.5
WP_000584387.1\|929241_930171_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-83	56.6
930048:930062	attL	NA	NA	NA	NA
WP_001791010.1\|930415_930532_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000691737.1\|930547_932467_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	97.2
WP_032506803.1\|932564_932753_+	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	7.4e-16	61.4
WP_001227349.1\|932810_933164_-	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-53	90.5
WP_000804878.1\|933695_934118_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	1.0e-49	70.0
WP_000845144.1\|934114_934345_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	7.9e-28	78.9
WP_000633909.1\|934840_935041_+	DUF3173 domain-containing protein	NA	NA	NA	NA
WP_000237798.1\|935067_936261_+\|integrase	site-specific integrase	A0A0S2MV79	Bacillus_phage	2.4e-43	34.0
WP_000129871.1\|936328_937891_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	4.9e-20	31.7
945684:945698	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1136094 : 1215981

Bacillus_phage(30.77%)

integrase,transposase,protease,tRNA

attL 1180547:1180564|attR 1224599:1224616

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088186184.1\|1136094_1137440_-\|transposase	IS3-like element IS861 family transposase	A0A1B1P773	Bacillus_phage	7.4e-65	50.4
WP_000129278.1\|1137515_1138283_-	hypothetical protein	NA	NA	NA	NA
WP_000022110.1\|1138291_1139002_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_000254651.1\|1138985_1140242_-	chloride channel protein	NA	NA	NA	NA
WP_000173383.1\|1140243_1141053_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_000416957.1\|1141091_1141499_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	7.7e-34	52.3
WP_000077191.1\|1141549_1142761_-	phosphopentomutase	NA	NA	NA	NA
WP_000343877.1\|1142817_1143489_-	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_001259482.1\|1143726_1144437_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_000863793.1\|1144526_1145315_-	esterase family protein	NA	NA	NA	NA
WP_001280054.1\|1145371_1147033_-	ribonuclease J	NA	NA	NA	NA
WP_000979970.1\|1147329_1148091_-	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	3.1e-12	29.3
WP_000587301.1\|1148090_1148954_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_000790858.1\|1148966_1149971_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000006716.1\|1150329_1151985_+	fibronectin/fibrinogen-binding protein	A0A1J0F9J4	Only_Syngen_Nebraska_virus	2.3e-07	41.0
WP_000005481.1\|1152038_1152758_-	acetolactate decarboxylase	NA	NA	NA	NA
WP_000140341.1\|1152771_1154454_-	acetolactate synthase AlsS	NA	NA	NA	NA
WP_000934868.1\|1154563_1155790_-	hypothetical protein	NA	NA	NA	NA
WP_001075588.1\|1155779_1156970_-	AI-2E family transporter	NA	NA	NA	NA
WP_000796047.1\|1157061_1157523_-	NUDIX hydrolase	NA	NA	NA	NA
WP_000163512.1\|1157512_1157995_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_000403410.1\|1158211_1161430_+	polysaccharide lyase 8 family protein	NA	NA	NA	NA
WP_000134275.1\|1161481_1162528_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	6.6e-69	43.6
WP_000139163.1\|1162734_1163328_-	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	NA	NA	NA	NA
WP_000676114.1\|1163327_1164197_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.7e-100	62.2
WP_000716829.1\|1164255_1165359_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_000647415.1\|1165367_1166156_-	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_000365673.1\|1166145_1166829_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_000221656.1\|1166932_1167613_-	DnaD domain-containing protein	Q938N2	Temperate_phage	1.9e-08	31.8
WP_000365343.1\|1167730_1168249_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	4.6e-31	44.1
WP_001247507.1\|1168371_1170936_-	GBS Bsp-like repeat-containing protein	NA	NA	NA	NA
WP_000622235.1\|1171087_1173286_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-72	29.1
WP_000124585.1\|1173282_1174044_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000405388.1\|1174045_1174975_-	ribonuclease Z	NA	NA	NA	NA
WP_000568320.1\|1175016_1175664_-	hypothetical protein	NA	NA	NA	NA
WP_000573351.1\|1175656_1176895_-	GTPase HflX	NA	NA	NA	NA
WP_001226480.1\|1176985_1177876_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_000239229.1\|1177986_1178163_+	DUF3042 family protein	NA	NA	NA	NA
WP_000823033.1\|1179252_1183011_-	pullulanase	NA	NA	NA	NA
1180547:1180564	attL	NA	NA	NA	NA
WP_001205490.1\|1183179_1183914_-	hypothetical protein	NA	NA	NA	NA
WP_000130587.1\|1183928_1184513_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_000150951.1\|1184609_1186016_-	dipeptidase PepV	NA	NA	NA	NA
WP_000670189.1\|1186062_1186665_-	nitroreductase family protein	NA	NA	NA	NA
WP_000942623.1\|1186834_1188616_+	glycerophosphodiester phosphodiesterase	I6XE30	Staphylococcus_phage	2.1e-06	25.0
WP_088186184.1\|1188672_1190018_-\|transposase	IS3-like element IS861 family transposase	A0A1B1P773	Bacillus_phage	7.4e-65	50.4
WP_001003955.1\|1190092_1191874_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_000567585.1\|1192032_1192800_+	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_000285045.1\|1192858_1194199_-	MATE family efflux transporter	NA	NA	NA	NA
WP_000245056.1\|1194298_1194715_-	VOC family protein	NA	NA	NA	NA
WP_000582587.1\|1194718_1195216_-	hypothetical protein	NA	NA	NA	NA
WP_000162278.1\|1195437_1196034_+	Ltp family lipoprotein	NA	NA	NA	NA
WP_088197863.1\|1196222_1197327_+\|transposase	IS3-like element ISSag2 family transposase	A0A2I7SC85	Paenibacillus_phage	6.3e-70	48.9
WP_000754588.1\|1199161_1201630_-	pneumococcal-type histidine triad protein	NA	NA	NA	NA
WP_000755138.1\|1201642_1202563_-	metal ABC transporter substrate-binding lipoprotein/laminin-binding adhesin Lmb	NA	NA	NA	NA
WP_001227840.1\|1204654_1208107_-	C5a peptidase ScpA/B	A0A218KC60	Bacillus_phage	7.6e-05	39.4
WP_000453221.1\|1208760_1210095_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_000584204.1\|1210202_1210751_-	hypothetical protein	NA	NA	NA	NA
WP_000863581.1\|1210847_1211078_-	hypothetical protein	NA	NA	NA	NA
WP_000248015.1\|1213363_1214599_+	hypothetical protein	NA	NA	NA	NA
WP_000157135.1\|1214778_1215981_-\|integrase	site-specific integrase	NA	NA	NA	NA
1224599:1224616	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1488859 : 1501120

Streptococcus_phage(90.91%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000767484.1\|1488859_1489687_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	4.3e-124	78.0
WP_000287943.1\|1489726_1490083_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.2e-42	72.6
WP_000966772.1\|1490084_1490561_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	7.1e-39	50.9
WP_001167085.1\|1491838_1492387_-	acetyltransferase	M1PSC3	Streptococcus_phage	1.1e-54	58.4
WP_000587955.1\|1492454_1493546_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.3e-163	77.1
WP_000603277.1\|1493678_1494314_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_000425856.1\|1494583_1495453_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	4.9e-110	70.4
WP_000358198.1\|1495452_1495779_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.2e-30	61.1
WP_000364562.1\|1495808_1496672_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.1e-72	49.0
WP_000715592.1\|1496691_1497327_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.8e-67	61.1
WP_000160598.1\|1497535_1498702_+\|transposase	IS30-like element ISSag9 family transposase	NA	NA	NA	NA
WP_001144245.1\|1498966_1499626_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	8.0e-65	56.0
WP_001185986.1\|1499644_1501120_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	8.2e-17	28.1

DBSCAN-SWA_6

2010017 : 2026188

Streptococcus_phage(71.43%)

integrase

attL 2009184:2009203|attR 2023591:2023610

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2009184:2009203	attL	NA	NA	NA	NA
WP_000381996.1\|2010017_2010524_-	DUF4065 domain-containing protein	D7RWK7	Brochothrix_phage	3.0e-35	48.8
WP_000038828.1\|2011017_2011404_-	ArpU family transcriptional regulator	A0A141E173	Streptococcus_phage	1.8e-08	32.8
WP_000500996.1\|2011378_2011741_-	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_000661533.1\|2012139_2012628_-	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	7.3e-47	56.2
WP_001258770.1\|2012712_2013318_-	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.4e-39	47.3
WP_001869738.1\|2013398_2014220_-	DnaD domain protein	R9QM95	Lactococcus_phage	1.2e-30	68.7
WP_000492119.1\|2014388_2014661_-	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	2.5e-28	69.8
WP_000174504.1\|2014653_2014995_-	hypothetical protein	NA	NA	NA	NA
WP_000206023.1\|2014991_2015354_-	hypothetical protein	NA	NA	NA	NA
WP_017645222.1\|2015365_2015557_-	hypothetical protein	NA	NA	NA	NA
WP_000877495.1\|2015556_2015889_-	hypothetical protein	NA	NA	NA	NA
WP_001259477.1\|2015977_2016484_-	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	2.2e-06	34.4
WP_000130289.1\|2016572_2016746_-	hypothetical protein	NA	NA	NA	NA
WP_001021393.1\|2016844_2017483_-	Bro-N domain-containing protein	NA	NA	NA	NA
WP_000648623.1\|2017705_2017948_-	hypothetical protein	NA	NA	NA	NA
WP_001258617.1\|2017974_2018595_-	phage repressor protein	A0A1W6JPC3	Staphylococcus_phage	2.2e-40	43.8
WP_000359663.1\|2018618_2018819_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001080841.1\|2019024_2019639_+	helix-turn-helix transcriptional regulator	A0A1X9I723	Streptococcus_phage	2.6e-17	68.7
WP_000946250.1\|2019650_2019938_+	DUF3102 domain-containing protein	A0A286QMZ8	Streptococcus_phage	1.9e-10	61.4
WP_000876115.1\|2020451_2020637_+	hypothetical protein	NA	NA	NA	NA
WP_000350953.1\|2020648_2020990_+	hypothetical protein	A0A1S5SDB5	Streptococcus_phage	2.2e-13	59.7
WP_000429449.1\|2021016_2021982_+	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	7.1e-86	51.1
WP_025194320.1\|2022319_2023486_+\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	5.6e-154	70.1
WP_000092759.1\|2023592_2024204_-	30S ribosomal protein S4	NA	NA	NA	NA
2023591:2023610	attR	NA	NA	NA	NA
WP_001278152.1\|2024533_2024821_-	Veg family protein	NA	NA	NA	NA
WP_000230635.1\|2024832_2026188_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.2e-152	62.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_HG939456

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection