CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP008815	Enterococcus faecalis ATCC 29212 plasmid 1, complete sequence	0 crisprs	NA	0	0
NZ_CP008816	Enterococcus faecalis ATCC 29212 chromosome, complete genome	2 crisprs	DinG,cas3,DEDDh,csa3,WYL	5	10
NZ_CP008814	Enterococcus faecalis ATCC 29212 plasmid 2, complete sequence	0 crisprs	csa3	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP008816_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008816_1

982928-983293

Orphan

II-A,II-B

Consensus_repeat	Method
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRISPRCasFinder
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	PILER-CR

5 spacers

The CRISPR arrays of NZ_CP008816_1

>merge|NZ_CP008816|1|982928-983293|CRISPRCasFinder,CRT,PILER-CR
GTGATAGTTTGTTTTTTAACAACATGGCTATAAAACAGGGGAGAAAAAGCCAAATCAAAAAAGTTTGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTATAACGTAAATCACAGTCTTTTGTAAGTCGTTTTGGTACCATTCCAAACAACATGACTCTAAAACATTAACGTAGTTGATTCAGAAAAACCAAGCGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTATGGTTTTGAATAAATTGTACATCATTATGTTTTGGTACCATTCTAAACAACATGACTCTAAAACCCTGTGGTCGGACAGGTGACGCCAGCAGATGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP008816|1|1|982928-983293|CRISPRCasFinder
GTGATAGTTTGTTTTTTAACAACATGGCTATAAAAC	AGGGGAGAAAAAGCCAAATCAAAAAAGTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATAACGTAAATCACAGTCTTTTGTAAGTC
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	ATTAACGTAGTTGATTCAGAAAAACCAAGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATGGTTTTGAATAAATTGTACATCATTAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCTGTGGTCGGACAGGTGACGCCAGCAGAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP008816|1|1|982928-983293|CRT
GTGATAGTTTGTTTTTTAACAACATGGCTATAAAAC	AGGGGAGAAAAAGCCAAATCAAAAAAGTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATAACGTAAATCACAGTCTTTTGTAAGTC
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	ATTAACGTAGTTGATTCAGAAAAACCAAGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATGGTTTTGAATAAATTGTACATCATTAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCTGTGGTCGGACAGGTGACGCCAGCAGAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP008816|1|1|983060-983293|PILER-CR
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	ATTAACGTAGTTGATTCAGAAAAACCAAGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TATGGTTTTGAATAAATTGTACATCATTAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCTGTGGTCGGACAGGTGACGCCAGCAGAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008816.1\|WP_002360016.1\|974504_975410_-\|prenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_CP008816.1\|WP_002414495.1\|984398_986480_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_CP008816.1\|WP_002364245.1\|973264_974476_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP008816.1\|WP_002364254.1\|989724_990849_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP008816.1\|WP_002360007.1\|991486_992632_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP008816.1\|WP_002362074.1\|988306_989545_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP008816.1\|WP_002362073.1\|987774_988290_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_CP008816.1\|WP_002356966.1\|986610_986976_-\|DUF1033-family-protein	unknown	unknown	gnl\|CDD\|336361
NZ_CP008816.1\|WP_002356959.1\|991074_991419_-\|DUF1831-domain-containing-protein	unknown	unknown	gnl\|CDD\|370163
NZ_CP008816.1\|WP_002356974.1\|981102_982521_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP008816.1\|WP_002360015.1\|975531_976512_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NZ_CP008816.1\|WP_002414562.1\|968828_969578_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP008816.1\|WP_002356976.1\|980092_981106_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
NZ_CP008816.1\|WP_002364244.1\|969695_970397_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP008816.1\|WP_002362065.1\|970527_972951_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NZ_CP008816.1\|WP_002364246.1\|976591_978358_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_CP008816.1\|WP_002364247.1\|978354_980088_-\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|274323
NZ_CP008816.1\|WP_002364256.1\|992788_993763_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039
NZ_CP008816.1\|WP_002364250.1\|983450_984314_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP008816.1\|WP_002364252.1\|987072_987642_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115

Protein	Function_ID	Function_description	E-value
NZ_CP008816.1\|WP_002360016.1\|974504_975410_-\|prenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	8.82053e-105
NZ_CP008816.1\|WP_002414495.1\|984398_986480_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP008816.1\|WP_002364245.1\|973264_974476_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	5.05823e-122
NZ_CP008816.1\|WP_002364254.1\|989724_990849_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP008816.1\|WP_002360007.1\|991486_992632_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	5.37018e-179
NZ_CP008816.1\|WP_002362074.1\|988306_989545_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.51661e-174
NZ_CP008816.1\|WP_002362073.1\|987774_988290_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	1.1162e-31
NZ_CP008816.1\|WP_002356966.1\|986610_986976_-\|DUF1033-family-protein	gnl\|CDD\|336361	pfam06279, DUF1033, Protein of unknown function (DUF1033). This family consists of several hypothetical bacterial proteins. Many of the sequences in this family are annotated as putative DNA binding proteins but the function of this family is unknown.	4.62165e-64
NZ_CP008816.1\|WP_002356959.1\|991074_991419_-\|DUF1831-domain-containing-protein	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.33245e-53
NZ_CP008816.1\|WP_002356974.1\|981102_982521_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NZ_CP008816.1\|WP_002360015.1\|975531_976512_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.52576e-80
NZ_CP008816.1\|WP_002414562.1\|968828_969578_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	3.4884e-110
NZ_CP008816.1\|WP_002356976.1\|980092_981106_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	9.60464e-103
NZ_CP008816.1\|WP_002364244.1\|969695_970397_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.52313e-37
NZ_CP008816.1\|WP_002362065.1\|970527_972951_-\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.48202e-174
NZ_CP008816.1\|WP_002364246.1\|976591_978358_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NZ_CP008816.1\|WP_002364247.1\|978354_980088_-\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|274323	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit. The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD.	0
NZ_CP008816.1\|WP_002364256.1\|992788_993763_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
NZ_CP008816.1\|WP_002364250.1\|983450_984314_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	5.07904e-27
NZ_CP008816.1\|WP_002364252.1\|987072_987642_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	3.60546e-15

>NZ_CP008816.1|WP_002356974.1|981102_982521_-|cytochrome-ubiquinol-oxidase-subunit-I
MFDIVTLARIQFAMTTVFHFFFVPFSIGLALVVAIMETMYVVKKEERYRKMAKFWGNIFLLSFAVGVVTGIIQEFQFGMNWSDYSRFVGDIFGAPLAVEALLAFFLESTFLGLWIFTWDKMNPKVHVTFIWLVVFGSMMSAFWILVANSFMQHPVGYVINNGRAEMVDFVAVISNPKVWYEFSHVIMGAFTLGGMAVAGMAAFQLLKKRDISFHKASMRIGLWVTLFGSIGVLLAGDLQMKALIEGQPMKFAAMEGAYEDSDDPAAWTLIAWADEREHKQVFGIDIPYMLSILSYNKLSGSVDGMDTVNKRLVEKYGDDKNYYPPVNTLFWSFRIMAGFGALMLLVAALGLFFTRKKKPSLYEKKWMLWIVALCTFAPFLANTTGWLVTELGRYPWTVYGLFTIEQSVSPNVSVASLITSNVIYFLLFAGLGSVMVYLVILELRKGPDYEAKKLAKENEPALDPFDKGVFGE
>NZ_CP008816.1|WP_002356976.1|980092_981106_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MSTLQLLWFVLIGVLFSGFFFLEGFDFGVGMAVQTLAHNDDEKDQVVATIGPVWDGNEVWLLTAGGAMFASFPYWYASLFSGYYLILFTILFGLIIRGVSFEFRHNMPEGKRRRMWNWTLSIGSFLVPFFFGILFISLVQGMPLDANGNMHAQFTDYFNLFSIVGGVALTLLCYLHGMNYIALKTEGPIRERARNYAEILYGVLYVGLVVFAVLMYFKTDFYEKNFAVTLILTLAIVVLTVIANVGVFKRKEMLAFLASGLTLVVLVALLFSGLFPRVMIGSEGFDLLIKDATSTPYTLKIMTWISLSILPFVLAYTAWSYYIFRKRISQTAVPEGY
>NZ_CP008816.1|WP_002364247.1|978354_980088_-|thiol-reductant-ABC-exporter-subunit-CydD
MIDKDILQMPKIKKILVLLAGFSFLQAVFIIGQAFFLSKAIVGLWSGGHLNQQLQSILLFFIFYLGRHVITYFRERMLDTFSYERSKELREQLLTKIFRLGPNVVQKNGTGNMVTMALEGISQTENYLQLILTKMMNMMIIPWIILAFVFTQDIRSGVTLLIVFPIIIIFMIVLGYAAQSKADKQYAAFQMLSNHFIDSLRGIDTLKLFGLSKKYAGSIYHTSERFRKATMSTLKIAILSTFALDFFTTLSVAVVAVFLGLSLLNGTILLFPALVTLILAPEFFLPIRDFSSDYHATLDGKNSFQAIQAVLALPEAEQTDVLTLDDWHQESQLSVTALNFSYEDATQEAIQSLQFSVDGRKKIGIIGASGSGKSTLINLLSGFLLPTEETSQLAINGQTIPHFLQKDWQKQILYIPQAPYIFQDTLANNIRFYTPEATDEAIQQAIQLVGLDELVKDLPEGIQTLIGESGRMLSGGQAQRVALARAFVDQKRHVLLFDEPTAHLDIETEVEMKERMLPLMNNHLVFFATHRLHWMEEMDYILVMEKGQLVEQGTLAELIEKDGYYVQLMKQMRGGRQ
>NZ_CP008816.1|WP_002364246.1|976591_978358_-|thiol-reductant-ABC-exporter-subunit-CydC
MMEKQPTTKDVWKNDQWVRPFLKRYKKTLYFALLLGFLTFFSAGALMFTSGYLISRAASLPENILLIYIPIVLTRAFGIGRPVFRYVERLTSHNWVLKMTSDLRLKLYNVLEKDAIFFKTKYRTGDILGLLSEDINHIQNLYLRTIFPTVIAWILYIFLVIALGFFSWWFALCMLLMLGVVVFLLPLVSVLVNGARQEKHKYAKNELYQTLTDNILGVSDWVFSQRGSEFVARYETDEANVRALDEKMKQFNRGRDFVLQLLFGVIAIAVLAWTSVRFPGNHGGAANWIGAFVLTVFPLIDAFAPLPAAAQETTIYKDSIRRFNELPEGEDDSTEAPVQPNGTSLSIEHLSFAYENQEKKVLNDLSLTIPEKQKLAILGRSGSGKSTLASLIRGDLRPTSGEILLGNIPTEAFGETMTEYIGVMHQAPYLFRTTILNNIRIGREEASEAEVWAVLEKVGLKEMVAQLPEGLQTMVDEAGLRFSGGERHRLALARILLQDTPIVLLDEPTTGLDPITEQQLLETFFEALKDKTVIWITHHLQGVTLMDQVIFIEDGQLEMSGTPEELLATNAHYQKLYRIDRGISSFEE
>NZ_CP008816.1|WP_002360015.1|975531_976512_+|polyprenyl-synthetase-family-protein
MNTFWKSFPDVERSLTETCELIEQTLHTRNEDIEEALVTLARSGGKLLRPAFFFLFAQLGDEEKQEKQQLLKIAASLEILHMATLIHDDIIDDSPLRRGAVTIQSQYGKDVAVYTGDLLFTEFFTLIADAMNGSEFMKINAQGMKRLLLGELDQMSHRFDRRMSIPAYLRSVNGKTAELFSLSCLEGAYFGHSSKEVQRLAKRIGRHIGIAFQVYDDILDYTADTETLKKPALEDLSQGVYTLPLLFAYQAAPDVFSPYLDKGRAITLEEAAEVAALVNDYHGVTEAQAFAKKVTNKAITDIQQLPDGTAKETLLSLTELLLHRSF
>NZ_CP008816.1|WP_002360016.1|974504_975410_-|prenyltransferase
MNREIFFELVELKAKTASVLPFLLGICFSWYQYGRLHVGYVLIFFIAMFIFNMAVDILDNYNDYHHATEVHDYKEKTNIIGRENLSLPLIRKMIFWMILVSALMGIGLSFIVGWPLLIMGLYCYLIGIFYSSGPKPLSSLPLGEVFSGFTMGFMITLICVYINTFEVFNWSAANLWGIFLVALPNTCYIANLMLANNICDLEEDENNKRYTLVHYLGKASSLKLFVGLNTIAMLAILLAVGLGLTPPTMLLMLLTLPFVRKQTQALLKEQVKSKTFVCAVKILAVGATAQVLFFAIGLWWL
>NZ_CP008816.1|WP_002364245.1|973264_974476_-|NAD(P)/FAD-dependent-oxidoreductase
MNKKHVVILGAGYAGLKTLRELQKGAKDVEITLVDRNNYHYEATDLHEVAAGTQPAEKITYNIMDVVDEKMTTFIQGTVKTIDAATQTVALEDGQTINYDYLVVSLGFESESFGIPGVQEHALQMVDVKTALNVYEHIQEQMRQYKATQNEEFLKIVVCGAGFTGIELLGSLVENKPKFAEIAGVSADQIQIYCVEAVTRLLPMFNEKLANYGVQLLKDSAIHLLLGKPIKEIKPGTVVYQDNEAGDLAELSAKTIIWTTGVSGSHVVGDSGFEARRGRVMVQPDLTDANHSNVYIIGDCSAVMDTETNRPYPTTAQIALKMGAHAAKNIQAQLKGEATKPFSFKSQGSVCSVGNTRALGIVGKTDIKGYPASFMKKIIMNKALFETGGTKEMMAKGRFDLYH
>NZ_CP008816.1|WP_002362065.1|970527_972951_-|DNA-translocase-FtsK
MAQKRSTNKKKSTTKKKTKKQQQQQERLNYMFLGLIFILFGVFGLFRLGFLGTLLANCLRLVVGNTFPFAAILLILYGLLVMIYGKDFPLKRGRPIFGAVLIYISVLLFFHAFMFRNVSGSQPDILGNTWEFLQSDLKANQVTQNVGGGMIGALLYQGTYFLVAQFGSYLIATLLLLAGIFLMSMWDFQQIVDHFQSIQDRLSHVSAKSQARQEEKEAKRAAKKEAKAAERQAKIEAAAQQKLQERERMEQAAADRLTKTPVETHQPMVEEPAAPTPVQIDSFQQQNQAMPVPPIAATKPQREQEEEAADEAGVLEFEISEEAEDRDYQLPPTDLLDTIQATDQSGEYEKIEKNIGVLEQTFKSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNSAISTVSFRDIVEAQPSHPDKLLEVPLGRDISGMVQTADLSKMPHLLIAGSTGSGKSVAINGIITGILMQAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTNPRKAAQALQKVVQEMEFRYEKFAATGVRNITGYNQLIQQKNAEDGENRPILPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDTNGAEKLLGRGDMLFLPMGENKPIRIQGAFISDQEVERVVAFVTDQQEAEYQESMMPTDEPTTSGGGEAPQDELFEEAKNLVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVIGPSEGSKPRKVFLQAESEEAAPETPEQ
>NZ_CP008816.1|WP_002364244.1|969695_970397_-|GntR-family-transcriptional-regulator
MRRKSVLYLEVADQIKEDILSGKYPVGTFLPTETELEELFNVSKITIRRAIEMLATEEFVEKKSGRGTTVLSNRPYNKLSKAGTFTEFLNESGQKVTKKVLQVENLTLSKEMPAYQFLGEEVVHLSRLYLIDEQPYIYFNYYLPAAMKDVSLTEYKEESLYRLMDRHAIEIYKFEDRFEVATLTEAEQKMLQTTETTGLKRIRRSLSPTGRCVEYSEAIYNTKIHPYVIEYEA
>NZ_CP008816.1|WP_002414562.1|968828_969578_-|ABC-transporter-ATP-binding-protein
MLEVQNLKKVYGNEIKYEALKGINLTVQDGEFIGIMGPSGSGKSTLLNLLATIDSPTDGEILLNGKNPNNLNQEQIAKFRRTELGFVFQSFNLMPTLTVEENIILPLTLDGEKVSVMKRQLAELSERLGINHLLKKRIAEISGGQAQRVAVARAMIHHPQLLLADEPTGNLDTKSSKDVMGLLQQLNEEEAATILMVTHDPLAASYCKRIVFIKDGELIDEIIQNGNQKEFYDIIMVKLAEIEGVDNEF
>NZ_CP008816.1|WP_002364250.1|983450_984314_-|AraC-family-transcriptional-regulator
MLANLNQAMDYIEEHLTEEVSFDELAKKTGISVYHFKRTFSFVAGMSLAEYIKKRRLAEANLALLAGKKVTDVAFKYGYQSIEGFSRAFRDWTGQAPSEVMKTQIQKTFPKFSFYIDIKGGQSMDVKLIEKPAFQIVGVSQKVPLQYQGENQAIMELAQRITPQQRAEMHTFDDVYPHQVVNASFDFQEGRTTEGGEMTHMIGFATSQENTYEDLEQLSVPAHTWAVFPNEGPFPQTLQETWARIFSEWLPSSGYQVVAAPEISFTQYQGPAEAKYSEIWLAVTATK
>NZ_CP008816.1|WP_002414495.1|984398_986480_-|DNA-topoisomerase-III
MVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLTVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDTKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTAKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
>NZ_CP008816.1|WP_002356966.1|986610_986976_-|DUF1033-family-protein
MYQVITMYGDNEPWWFFDDWQEDIVQEKTFDNLTDAETYYVEVWQKLSQNYTYVNTKPNYLTAFWNDGEERWCEECDEDLQQYFGLALLENHHAVTFENKAEFTTISNHFGKTKFCKRKVI
>NZ_CP008816.1|WP_002364252.1|987072_987642_-|TetR/AcrR-family-transcriptional-regulator
MAKKRNLTKAKILESARNLAEELGVQQLTFQNLAVDLGIKYPSLYNHFKNIAEVKNALVDLLIQELNDALRRALVGKSGAEAIRIYAETYQQFAFENSAVYELLISVPKTQNQQLIEGIHETNQIILQLLAFYPFNNEERLHKSRELRSLIHGYITLRFLGYFQREEATPEESYRRMIEDFIASLEVAR
>NZ_CP008816.1|WP_002362073.1|987774_988290_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MHITNRSHLADRYGKRTSAEFLLHERPILSFPISLAAIPKEARYLSWELIDYDTIPLIGFPFIHWLAANVPVTNEIPEDFSRTALKPTIQGKNSLASPLGKQMIPALATETLPELTERYLGLSPRSGVHTYTLYVYATKNPLNLKEGFFANELHQALNDQRLAKAKFEFLY
>NZ_CP008816.1|WP_002362074.1|988306_989545_+|multidrug-efflux-MFS-transporter
MYELIKSKIFRPRQPWEKNLLVLWFGTFMAGIGFSLVMPFMPLYINTLGTFTHQQLNFWSGITFSSTFLVTTIVSPWWGRLADRKGRKLMLLRASLGMAIVISLMGAVTSVYQLIGLRLLQGVFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTLLGPLLGGVTASIFGYRPTFFITGTILLLVFVLSLVFVHEEFVPIEKNQAASGKQILKKLEHPHVILGMFITTLIIQASNNSISPIISLYIQQLLGGHGNVTLISGVIASIPGIATLIAAPRFGRLGDRIGSERILTIGLILAIFVYLPMAFVQNVWQLAMLRFLVGISDACLLPAVQTLITRYSPSDAAGRIFSYNQSFQATGNVIGPMIGSSVSAAFGYRGVFISTSCLVLLNLLWVRRSTAELKKEKNDD
>NZ_CP008816.1|WP_002364254.1|989724_990849_-|tRNA-2-thiouridine(34)-synthase-MnmA
MADNSKRRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVAKVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRLGRTPNPDVMCNKEIKFKAFLDYAMQLGADYVATGHYAQVETDENGVVHMLRGIDNNKDQTYFLSQLSQAQLAKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGVCFIGEKNFKEFLSNYLPAKKGNMVTEDGEIKGQHDGLMYYTIGQRQGLGIGGGGKTQEPWFVIGKDLTTNTLYVGQGFHHEKLYATHLEASEVHFTVDTPMPKEFDCTAKFRYRQADIPVHVSLSEDGTKATVTFKEPARAVTPGQAVVFYDGMECLGGGLIDRAYQDEKELQYV
>NZ_CP008816.1|WP_002356959.1|991074_991419_-|DUF1831-domain-containing-protein
MAFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKPMNIFKNEQHEMSKEKYFFLMDGLISRGVLEKVE
>NZ_CP008816.1|WP_002360007.1|991486_992632_-|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQTIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKINGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSAEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHLKGIPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK
>NZ_CP008816.1|WP_002364256.1|992788_993763_-|ribose-phosphate-diphosphokinase
MTENYQDDTLRIFSLNANRPLAEKIAASVGTELGKSTVRQFSDGEIQINIEESIRGDHVYIIQATNAPVNDHLMELLILIDALKRASAKTINVILPYYGYARQDRTAKPREPITAKLVANMLVEAGATRLLTLDLHTVQVQGFFDIPVDNLFTMPLFAHYYRQQALVGEEIVIVSPKNSGVQRARSLSEYLDATLAIVDHEEIDGVRQEGYVIGNVAGKKCILVDDILNTGQTLATAAEVLMKNGAQEVYACASHGLLSEGAKATLENAPIKEISITDSVYTTADRQPATLNIISCAELMGEALLRIHENKPMSPLFRLESKGE

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Crispr_ID: NZ_CP008816_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008816_2

1918628-1918701

Orphan

Consensus_repeat	Method
ATAGTTGGCGAGCAACAGAAAAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP008816_2

>merge|NZ_CP008816|2|1918628-1918701|CRISPRCasFinder
ATAGTTGGCGAGCAACAGAAAAACTCGATATAGAATTGGACGTAGAGCCAATAGTTGGTGAGCAACAGAAAAAC

>NZ_CP008816|2|2|1918628-1918701|CRISPRCasFinder
ATAGTTGGCGAGCAACAGAAAAAC	TCGATATAGAATTGGACGTAGAGCCA
ATAGTTGGTGAGCAACAGAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008816.1\|WP_002354863.1\|1929194_1930751_-\|ribonuclease-Y	unknown	unknown	gnl\|CDD\|237177
NZ_CP008816.1\|WP_002354869.1\|1922458_1923013_-\|septum-formation-protein-Maf	unknown	unknown	gnl\|CDD\|238310
NZ_CP008816.1\|WP_002380978.1\|1925201_1927778_-\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NZ_CP008816.1\|WP_002381060.1\|1920742_1921714_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP008816.1\|WP_002394745.1\|1912868_1913573_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP008816.1\|WP_002354883.1\|1912373_1912823_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NZ_CP008816.1\|WP_002371653.1\|1906244_1907645_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368093
NZ_CP008816.1\|WP_002365385.1\|1908007_1908262_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008816.1\|WP_002392696.1\|1919602_1919746_-\|putative-holin-like-toxin	unknown	unknown	gnl\|CDD\|319017
NZ_CP008816.1\|WP_002354864.1\|1928237_1929035_-\|TIGR00282-family-metallophosphoesterase	unknown	unknown	gnl\|CDD\|379099
NZ_CP008816.1\|WP_002354884.1\|1910896_1912165_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_CP008816.1\|WP_002354868.1\|1923037_1925170_-\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|223400
NZ_CP008816.1\|WP_002360992.1\|1908565_1909432_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224343
NZ_CP008816.1\|WP_002354866.1\|1927778_1928150_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226923
NZ_CP008816.1\|WP_002354871.1\|1921888_1922326_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP008816.1\|WP_002354875.1\|1917702_1918353_+\|beta-phosphoglucomutase	unknown	unknown	gnl\|CDD\|213672
NZ_CP008816.1\|WP_002404005.1\|1914943_1917688_+\|glycoside-hydrolase-family-65-protein	unknown	unknown	gnl\|CDD\|224471
NZ_CP008816.1\|WP_002414925.1\|1909599_1910904_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_CP008816.1\|WP_002354889.1\|1907635_1907998_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008816.1\|WP_002390676.1\|1932306_1933575_-\|competence/damage-inducible-protein-A	unknown	unknown	gnl\|CDD\|234789

Protein	Function_ID	Function_description	E-value
NZ_CP008816.1\|WP_002354863.1\|1929194_1930751_-\|ribonuclease-Y	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0
NZ_CP008816.1\|WP_002354869.1\|1922458_1923013_-\|septum-formation-protein-Maf	gnl\|CDD\|238310	cd00555, Maf, Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.	1.6551e-85
NZ_CP008816.1\|WP_002380978.1\|1925201_1927778_-\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NZ_CP008816.1\|WP_002381060.1\|1920742_1921714_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP008816.1\|WP_002394745.1\|1912868_1913573_-\|hypothetical-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	3.13542e-11
NZ_CP008816.1\|WP_002354883.1\|1912373_1912823_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	2.8499e-49
NZ_CP008816.1\|WP_002371653.1\|1906244_1907645_-\|hypothetical-protein	gnl\|CDD\|368093	pfam04740, LXG, LXG domain of WXG superfamily. This domain is present is the N-terminal region of a group of polymorphic toxin proteins in bacteria. It is predicted to use Type VII secretion pathway to mediate export of bacterial toxins.	5.75414e-14
NZ_CP008816.1\|WP_002392696.1\|1919602_1919746_-\|putative-holin-like-toxin	gnl\|CDD\|319017	pfam16935, Hol_Tox, Putative Holin-like Toxin (Hol-Tox). Hol_Tox is a family of small proteins (34-48aas) with a single TM region. Members can exhibit antibacterial activity against Gram-positive bacteria but not against Gram-negative bacteria.	3.57939e-12
NZ_CP008816.1\|WP_002354864.1\|1928237_1929035_-\|TIGR00282-family-metallophosphoesterase	gnl\|CDD\|379099	pfam13277, YmdB, YmdB-like protein. This family of putative phosphoesterases contains the B. subtilis protein YmdB.	2.68643e-155
NZ_CP008816.1\|WP_002354884.1\|1910896_1912165_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.15225e-51
NZ_CP008816.1\|WP_002354868.1\|1923037_1925170_-\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|223400	COG0323, MutL, DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair].	0
NZ_CP008816.1\|WP_002360992.1\|1908565_1909432_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	8.53832e-35
NZ_CP008816.1\|WP_002354866.1\|1927778_1928150_-\|hypothetical-protein	gnl\|CDD\|226923	COG4550, COG4550, Predicted membrane protein [Function unknown].	8.72333e-15
NZ_CP008816.1\|WP_002354871.1\|1921888_1922326_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.48715e-93
NZ_CP008816.1\|WP_002354875.1\|1917702_1918353_+\|beta-phosphoglucomutase	gnl\|CDD\|213672	TIGR01990, bPGM, beta-phosphoglucomutase. This model represents the beta-phosphoglucomutase enzyme which catalyzes the interconverison of beta-D-glucose-1-phosphate and beta-D-glucose-6-phosphate. The 6-phosphate is capable of non-enzymatic anomerization (alpha <-> beta) while the 1-phosphate is not. A separate enzyme is responsible for the isomerization of the alpha anomers. Beta-D-glucose-1-phosphate results from the phosphorylysis of maltose (2.4.1.8), trehalose (2.4.1.64) or trehalose-6-phosphate (2.4.1.216). Alternatively, these reactions can be run in the synthetic direction to create the disaccharides. All sequenced genomes which contain a member of this family also appear to contain at least one putative maltose or trehalose phosphorylase. Three species, Lactococcus, Enterococcus and Neisseria appear to contain a pair of paralogous beta-PGM's. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. These enzymes are characterized by a series of three catalytic motifs positioned within an alpha-beta (Rossman) fold. beta-PGM contains an inserted alpha helical domain in between the first and second conserved motifs and thus is a member of subfamily IA of the superfamily. The third catalytic motif comes in three variants, the third of which, containing a conserved DD or ED, is the only one found here as well as in several other related enzymes (TIGR01509). The enzyme from L. lactis has been extensively characterized including a remarkable crystal structure which traps the pentacoordinate transition state. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	7.1375e-106
NZ_CP008816.1\|WP_002404005.1\|1914943_1917688_+\|glycoside-hydrolase-family-65-protein	gnl\|CDD\|224471	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism].	1.16272e-173
NZ_CP008816.1\|WP_002414925.1\|1909599_1910904_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	4.48881e-85
NZ_CP008816.1\|WP_002390676.1\|1932306_1933575_-\|competence/damage-inducible-protein-A	gnl\|CDD\|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	0

>NZ_CP008816.1|WP_002354875.1|1917702_1918353_+|beta-phosphoglucomutase
MTIGFIFDLDGVITDTAKFHYQAWKALADSLGISIDETFNETLKGISRMDSLDRILAHGHRENAFTPAEKEALAQQKNDHYVQLLEHLTTEDVLPGVVPLLQQAQARHIPCAVASASKNAPLILEKLGVRAYFATIVDPDSLSKGKPDPEIFLAAADSIGVLPQNAIGFEDAQSGIDGLKAAGIYAVGLSASQPLIGADMQVSEMTELSVDALLNR
>NZ_CP008816.1|WP_002404005.1|1914943_1917688_+|glycoside-hydrolase-family-65-protein
MSIQVHKEAPNMTILELTFATNQLTTTFFNHKLEPLHQKTFPFEALTIEETVPELCQLIVAEAAPILGGIVADFPEDFFSPEETLALVPQAVIQAFAEQLNTPLLTAAEQVAAPNLLAAFEEKRQYLAWHLDYYGYVPGKNEYAVESLLTVGNGFLGLRGTTPEMTISDDHYPATYIAGLYNTAASEVAGQVVENEDFVNAPDNQHIALKIGDATDWLTISPDTLQQLHRQLNLKTGLFVAEMILKDADNQQIKLTTKKIANMAQPNDYHLQYTFEPLNFSAPITLKTVTDGSVYNYNVARYRNLTAKHFQVTALSAQENKTVIEVCTNQSNLSVRETALITGDFFEKEAITIQEEAEKIAQVVTVMAHQGTRYTLEKQVFVQASHAEQSWQVPFTPKDSFAAAAQESARAWQTLWQQANITVTGDLMSQKLLRIHSYHLLASASPFSNQAQALDVSITARGLHGEAYRGHIFWDEIFILPFYIQHYPDTAKQLLLYRYHRLEKAKENAAASQYRGAMYPWQSGRDGRETTQKLHLNPLNGHWGEDHSILQRHVSLAIAYNAWLYWHSTQDHEFMKQYGGEMLLEIAQFWNSAATLDDATGRFFIDKVMGPDEFHEGYPDQAESGLKNNAYTNLMVVWLFEELTNILALFSEEEQAQLFAKTQTSSADLARMQQIQNSLEIEVNSDGIIAQYEGYFGLKEIDWAAMKEKYGNIYRMDRILKAEGESPDDYKVAKQADTLMLFYNLDKTRVDQILEDLGYQLPADYLEKNLLYYLKRTSHGSTLSRIVHAQLAEMAQFHELSWQLYQEALYSDYRDIQGGTTAEGIHTGVMAATIHVTLATYAGVDTRQNELSICPNLPEHWQALAFQFIHQGVTYQFSLTQTSVTITADKDTQLLVQGALIPLTAERPKEVHYQ
>NZ_CP008816.1|WP_002394745.1|1912868_1913573_-|hypothetical-protein
MKKKIMASLLVGSAVVGASLAPLSAQAVTTGNTPVQVEFGGGVLPDHENSTGGALDPDPTKPNTDFDLLAVPRSFDFPLAKINDDLSAIKETSRVIRDIMVGDVRGTKEGWHVTGELTKMSNGTDELAGDINFELEVSYAEYVTHITPPYYGAAPTLNGINIANDPTAPSAIGTNIKIGGGATVLMNATVGKGQGTWAGRFGNMTLNVTTPMQELKKGAYTGNITWNLVAGPSI
>NZ_CP008816.1|WP_002354883.1|1912373_1912823_+|large-conductance-mechanosensitive-channel-protein-MscL
MIKEFKEFIMRGSVLDLAVGVVIGSAFTAIVTQVVEGLITPLISLIFVLTTGKKSADDALGALVYKVEGVEFNIGSVISALITFLITAFVLFLIVKAANKMKNRGKKEEAAEEEVVPTSEDYLKEIRDLLAAQTPPAETVKTDSTFTEK
>NZ_CP008816.1|WP_002354884.1|1910896_1912165_-|insulinase-family-protein
MSVQLVKGVNLHVIPTEKYKTVRLLVRFNTRLNHETITKRTLLSSLMETNSLNYPNQVKLSERLAELYGASFGIGVSKKGNQHWFNISMNIVNDHYLQDSQVLAEAVDFLKEIIFAPNIQAGQFEAETFQREKENLKAYLESIVEDKQTYASLALQSVYFNQSEDQKIPSFGTVAALAEETAASLAAYYQKMLAEDQVDIFVLGDVNEAELVPLFKQLPFTPREEGKAAIFYNQPIRNVIEERTEREVLAQSKLNLAYNTDIYYGDSYYFALQVFNGIFGGFPHSKLFMNVREKEHLAYYASSSIDTFRGFMTVQTGIDGKNRNQVLRLISTELENIRLGKISELEIEQTKAMLKNQYILALDNAGAWLEKEYLNELMPQTMLTAEEWIARINAVTISEIQEVAKRLELQAIFFLEGETEND
>NZ_CP008816.1|WP_002414925.1|1909599_1910904_-|insulinase-family-protein
MIKKDYAQIKETLYTETLANGLKVYLLPKNDFQKTYGLFTTDYGSIDNTFVPIGQEEMIEVPDGIAHFLEHKMFEKEDGDVFQKFGQQGASANAFTSFTKTSYLFSTTDQVTQNLETLLDFVQSPYFTKETVEKEKGIIGQEIQMYLDDPNWCLFFGILGNLYPKHPLHIDIAGTVASIAEITAEDLYTCYNTFYHPSNMTLFVVGKMDPEALMAFIRENQAAKEFPAAQPIRRHFPEETAADIVKESAIEMAVTRAKVLVGLKGLDEVPTTGRDLMKYQVTVNLLLQLLFGNTSQNYLALYDEGLLDDSFSYDFNLDRSFHFADIGGDSEQPEVLAERIEAILLSATTSPELTEENLSLLKKKMIGKYFQSLNSLEYIANQFSQSLFGETTLFDKIEVIESIQLADVRQVAETLIREEGLSRFYMYPKGETEQ
>NZ_CP008816.1|WP_002360992.1|1908565_1909432_-|helix-turn-helix-domain-containing-protein
MASVNIGETLKEARLQKNISIDELQQMTKIQKRYLEIIEQNDFESLPGTFYVRAFIRQYASAVGLDGNQLVDIYDGKEPAIVEEPKPVYEELEGSRKQLHDEEKQSSWLLRNLPAIAFSLIGLAIAVVVLYIMWQDQKAEPIIQTPATSASVEKPKESSQAPESSTQSSTPPSSSSEPEKKTAVAVVSDANNQVTATVKDANSPINITFKGTEGSCWIGVMVDGNYTYQHTLQAGETETTALPANAANATLILGASNNVAIQVDGADLTLEKTPVLIRKDVTLGITYR
>NZ_CP008816.1|WP_002365385.1|1908007_1908262_-|hypothetical-protein
MVKIASNQGAAQKAIAGIKNVSVNKNQTCHLGESNISSMKKGVKVSNQLLNQLAKVVNGVNAQANKFPKLAATIAARDSQTTFK
>NZ_CP008816.1|WP_002354889.1|1907635_1907998_-|hypothetical-protein
MEKDTNEKLRRNYAEQIVEKERAMDQLSKEKKQIQTIFGTLESELTRNFRELEQLNAEVIHKGGKSTRWEQEELSGKQRYLRGFLQQQTHELSQRYTKATAQSNEERLQLQRERSRLSWD
>NZ_CP008816.1|WP_002371653.1|1906244_1907645_-|hypothetical-protein
MGLIYSSSDSSAMMRALSSNLAVARTTTSELTAGCQQLIAAIDGHTLSGAAYNAGKGLFSELVIPTIHRMTAAVDNVQSDLAKYSAADAFIASEGFLDEDKLKLKIKIMKANQQLLHDSARAVATLAHSQPIPGIYELLQNAQRTFIKMAESMQQDIDKLHKQIRKLNEFDRQTKNLFATSLEEMQLAMQGILVLNETTVKSNGLYTLPSGVDKSYFTEIKKEASTVLETAKPKIELINKTDSLEEISRKTIACANIGINPYTGKKISQKEANKFKYAAWAGTLTEVGNVVLGSYYGNKTASRLKNSGQGKKSIKPKYDDIYTYQYNGYDNPGPLNDIKGQPNRNFYGGRYDMEVLKEPKILYRAGDGKNPLGQWFTESPPNSVANVRIDTAVKPQWIDRNGSFTGASNIDRVYKIEIPAGTTIYSGPVGNQGSIYQGGMNTNQIFIKRPWEFGDKITILGSSPLK
>NZ_CP008816.1|WP_002392696.1|1919602_1919746_-|putative-holin-like-toxin
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK
>NZ_CP008816.1|WP_002381060.1|1920742_1921714_-|ribose-phosphate-diphosphokinase
MSKHYFDPRLKIFSLNSNRPLAEKIADAVGVELGKCSVTQFSDGEIQVNIEESIRGAHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYARQDRKARAREPITAKLVANMIEKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIADYFIEHGIQGDDVVVVSPDHGGVTRARKLAEFLKAPIAIIDKRRPKANVAEVMNIIGHVEGKTCVLIDDMIDTAGTISLAANALKEAGAKDVYASCTHPVLSGPALQRIEDSAIERLVVTDSIYLSDDRKIAKIDEVSVGELIGDAIKRIHENKPVSPLFETKNK
>NZ_CP008816.1|WP_002354871.1|1921888_1922326_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MTKPTEEELKQTLTDLQYAVTQENATERPFSGEYDDFYQDGIYVDIVSGEPLFSSLDKYDAGCGWPSFTKPIEKRGVKEKADFSHGMHRVEVRSQEADSHLGHVFTDGPLQEGGLRYCINAAALRFVPVADLEKEGYGEYLSLFK
>NZ_CP008816.1|WP_002354869.1|1922458_1923013_-|septum-formation-protein-Maf
MQIILASQSPRRQELLKRVVPTFTIAPADIDETVGKDGLPAEYVAQMAAQKAAAIAEQSPEALVIGCDTIVALAGEILGKPTSREDGYRMLRLLSGKTHDVYTSVTLKQGEKERSATVHSTVTFYPLTDTEIHAYLDTAEYADKAGAYGIQGQGALLIEAIAGDYYAIMGLPIAKVARLLKEFN
>NZ_CP008816.1|WP_002354868.1|1923037_1925170_-|DNA-mismatch-repair-endonuclease-MutL
MGKIQELSEQLANQIAAGEVVERPASVVKELVENALDAGSTQIDIFIEEAGLKTIQIIDNGEGIAKEDVLNAFKRHATSKIHTRDDLFRIRSLGFRGEALPSIASVSEMIVETATAEEEEGSYVILKGGKVEENRPAALRKGTKMTVSNLFYNTPARLKYVKTIQTELANIGDIVNRLALSHPKVAFRLVHDGHKMMSTTGNGDLKQTIAGIYGISTAKKMLKIEGKDLDFTLTGYVSLPEVTRASRNYLSTIINGRYIKNFALNKAIVAGYGSKLMVGRFPIAVLEIEMDPLLVDVNVHPTKQEVRLSKEKDLMALIEQAIQEVLSQEQLIPNAADNLRFKKKLPPEPKAEQMEIPLSTEQPAVKQRPGSLSYNPATGRFYAEHATDETPASSAPEAVNQTERAVDPMDDPFAPPVPESTSVAEETSAYETSSAAVDSENHWETASNEQQVIAEETKITEVPDSEPSLRSSEAADEVFQEEMKLHPEFDANSATSQRELKQALNKLEEERPTERFPELEYFGQMHGTYLFAQSKDGLFIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPIVIDYPNSDALKIKEQKETLAEVGIHLEDFGQNSFIVRAHPTWYPAGEEESIVREMIDMLLTTGSVSVKKFREATAIMMSCKRSIKANHYLNEQQARVLLKDLALCENPFNCPHGRPVLIHFTNSDMERMFKRIQDPH
>NZ_CP008816.1|WP_002380978.1|1925201_1927778_-|DNA-mismatch-repair-protein-MutS
MPQKTKNTPMMEQYLSIKAQYKDAFLFYRLGDFYELFYEDAINAAQILELTLTSRNRNADDPIPMCGVPYHAAQGYIDTLIEQGYKVAICEQVEDPKTTKGMVKREVVQLVTPGTVMNSKGLEAKDNNYLTAVLTDGNQFGFAYVDLSTGELKTAVLADEEGVLNEASALQTKEMVLGSGIPESLKENLSLRLNIIFSTQETVEENAEFSFLTNELINPLEIEITGKLLSYLSVTQKRSLSHIQKAVEYQPDHFLKMDHYSKFNLELSQSIRTGQKKGTLLWLLDETKTAMGGRLLKQWLDRPLIQERQIKTRQEMVQSLLNSYFERLDLQAALTNVYDLERLAGRVAFGSVNGRDLIQLRTSLEQVPTIRQLIVGINQGEWDDLLVDLNPVEDLVELIATAINEEAPLQITEGNVIKDGYNDQLDEYRDAMRNGKQWLAELEAKERQETGIKNLKIGYNRVFGYFIEITKSNLANLEEGKYERKQTLANAERFITPELKELERLILEAEEKSVELEYQLFLAVREQVKTNIDRLQTLAKTISAVDVLQSFATISERYQYVRPTLRSNTKNLAIVEGRHPVVEKVLGHQEYIPNSIRMNPETDILLITGPNMSGKSTYMRQLALTVVMAQIGCFVPAESAEMPIFDQIFTRIGASDDLIAGQSTFMVEMMEANQALRHATPNSLILFDELGRGTATYDGMALAQAIIEYIHREVQAKTLFSTHYHELTVLDETLKGLKNIHVGAVEKDGEVVFLHKMMEGPADKSYGIHVAKIAGLPSPLLERAATILSALEAEETTIPSSVHHEEVSEVHEETEQLSLFKEVSTEELSVIDTLKKMNLLEMTPLDALNMLHQLQKRI
>NZ_CP008816.1|WP_002354866.1|1927778_1928150_-|hypothetical-protein
MEPLNLDAQSNKELEKLLHLIGQDEVIQRYQAIEEKVKKNKKLTELVEEIKAAQKDAVQFAHYGKPTAEKEAIQRADAKTKEFDEHPLVVAYREQLIEANDLVQHVTALIQYRVNEELEKEGN
>NZ_CP008816.1|WP_002354864.1|1928237_1929035_-|TIGR00282-family-metallophosphoesterase
MRILFIGDVVGSLGREALATYVPKLKKKYRPQVTIANGENAASGRGITGKIYKKFLQDGVDVVTMGNHTWDNKDIFEFIDDAKKMVRPANFPEDVPGQGMVFVKVNQLELAVINLQARTFMVPLEDPFKKAAELVAIARKRTPLIFVDFHGETTSEKQAMSWFLDGQVSAVVGTHTHVQTNDARILPKGTAFLSDVGMTGPYDGILGMKREPIIEKFMTALPKRFEVVETGRTILSACILEIDDQTGQAKMIEPIQISEDRPFQE
>NZ_CP008816.1|WP_002354863.1|1929194_1930751_-|ribonuclease-Y
MVLNILLAIVGLIVGLGLGFVIAKSRHDKAINGAKISASSILENARKESETLKKEALLEAKEENQKYRSEIESELKESRLELKSQENRLIQREQTLDRKDDSLEKREGSLEEKEEKLGARQQLIDEREKEVENLINQQHQELERIASLSKEEAKSIIMKSTEEELNHELTLMVKESEQRAKEESDRKAKNLLSLAIQRCAADSVSETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPARIEEMVEKSRKEMDERIREYGEQAAFEVGAHTLHPDLIKILGRLRFRTSYGQNVLNHSIEVAKLAGVLAAELGEDVQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYKENSVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLENLENISNSFEGVDSSFAVQAGREVRVMVKPEEISDLESVRLVRDIRKKIEDDLDYPGHIKVTVIRETRAVDYAK
>NZ_CP008816.1|WP_002390676.1|1932306_1933575_-|competence/damage-inducible-protein-A
MLLEKGKSMKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQVVAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMFQQAARPLLINAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATEEKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISHELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVMRGLDLLRRRIINKK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	MF157411	Escherichia coli strain EC1000 plasmid pCR2, complete sequence	304-333	0	1.0
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	MH375074	Enterococcus phage LY0323, complete genome	32049-32078	0	1.0
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	NC_042127	Enterococcus phage vB_EfaS_AL2, complete genome	31836-31865	0	1.0
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	NC_031260	Enterococcus phage Ec-ZZ2, complete genome	21847-21876	0	1.0
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	KF733017	Enterococcus phage IME-EF4, complete genome	31981-32010	0	1.0
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NZ_CP022485	Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence	4124-4153	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	38052-38081	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	1579-1608	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	CP002493	Enterococcus faecalis 62 plasmid EF62pB, complete sequence	38720-38749	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	43030-43059	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	47853-47882	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	53323-53352	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NC_006827	Enterococcus faecalis plasmid pCF10, complete sequence	59015-59044	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	40051-40080	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NZ_CP028283	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed3, complete sequence	4491-4520	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NZ_CP042215	Enterococcus faecalis strain L15 plasmid pL15-A, complete sequence	4208-4237	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NZ_MG765452	Enterococcus faecalis strain E512 plasmid pE512, complete sequence	16118-16147	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	41009-41038	1	0.967
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	CAJDJX010000002	Enterococcus phage Q69 genome assembly, contig: phageQ69-genome, whole genome shotgun sequence	31516-31545	1	0.967
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	CAJDKF010000002	Enterococcus phage vB_EfaS_159 genome assembly, contig: phage159-genome, whole genome shotgun sequence	10682-10711	1	0.967
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	NZ_CP041739	Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence	24217-24246	2	0.933
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	MK721199	Enterococcus phage vB_EfaS_Ef5.1, complete genome	28065-28094	2	0.933
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	MK721190	Enterococcus phage vB_EfaS_Ef6.4, complete genome	27969-27998	2	0.933
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	MK721200	Enterococcus phage vB_EfaS_Ef5.3, complete genome	28357-28386	2	0.933
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	NC_031260	Enterococcus phage Ec-ZZ2, complete genome	981-1010	2	0.933
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	KF733017	Enterococcus phage IME-EF4, complete genome	11644-11673	2	0.933
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	CAJDKF010000002	Enterococcus phage vB_EfaS_159 genome assembly, contig: phage159-genome, whole genome shotgun sequence	8300-8329	2	0.933
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	MT119359	Enterococcus phage heks, complete genome	11839-11868	2	0.933
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	CAJDJX010000002	Enterococcus phage Q69 genome assembly, contig: phageQ69-genome, whole genome shotgun sequence	11642-11671	2	0.933
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	MK125140	Enterococcus phage Nonaheksakonda, complete genome	7356-7385	2	0.933
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	MK982307	Enterococcus phage MSF2, complete genome	14541-14570	2	0.933
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	CAJDKF010000002	Enterococcus phage vB_EfaS_159 genome assembly, contig: phage159-genome, whole genome shotgun sequence	32054-32083	3	0.9
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	KF728385	Enterococcus phage IME_EF3, complete genome	29904-29933	3	0.9
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	KJ127304	Enterococcus phage AUEF3, partial genome	19398-19427	3	0.9
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	MK125140	Enterococcus phage Nonaheksakonda, complete genome	9734-9763	3	0.9
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	MG264739	UNVERIFIED: Enterococcus phage phiNASRA1, complete genome	19944-19973	3	0.9
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	NZ_CP042332	Bosea sp. F3-2 plasmid pB32-1, complete sequence	413391-413420	5	0.833
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	MK496783	Capybara microvirus Cap3_SP_410, complete genome	3412-3441	6	0.8
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	MN693358	Marine virus AFVG_25M395, complete genome	6141-6170	6	0.8
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	MN694190	Marine virus AFVG_250M608, complete genome	30089-30118	6	0.8
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	MT074134	Bacteroides phage ARB14, complete genome	36880-36909	6	0.8
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	MT074143	Bacteroides phage HNL05, complete genome	37280-37309	6	0.8
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	MT074135	Bacteroides phage ARB25, complete genome	36793-36822	6	0.8
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	MT074144	Bacteroides phage HNL35, complete genome	37321-37350	6	0.8
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NC_014502	Gloeothece verrucosa PCC 7822 plasmid Cy782203, complete sequence	268334-268363	7	0.767
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP032754	Lactobacillus plantarum subsp. argentoratensis strain DSM 16365 plasmid unnamed3, complete sequence	26827-26856	7	0.767
NZ_CP008816_1	1.2\|983030\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	983030-983059	30	MN694044	Marine virus AFVG_250M514, complete genome	29776-29805	7	0.767
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	NZ_CP011146	Bacillus cereus strain FORC_013 plasmid pFORC13, complete sequence	156576-156605	7	0.767
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP028270	Pediococcus pentosaceus strain SRCM102740 plasmid unnamed1, complete sequence	22740-22769	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP028267	Pediococcus pentosaceus strain SRCM102739 plasmid unnamed1, complete sequence	9446-9475	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP015919	Pediococcus pentosaceus strain wikim20 plasmid pKPP01, complete sequence	11178-11207	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP021931	Lactobacillus plantarum strain TMW 1.1308 plasmid pL11308-1, complete sequence	27801-27830	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP024059	Lactobacillus plantarum strain KACC 92189 plasmid unnamed1	53320-53349	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP028265	Pediococcus pentosaceus strain SRCM102738 plasmid unnamed1, complete sequence	32031-32060	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP018326	Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-2, complete sequence	38976-39005	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP019582	Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence	10189-10218	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP035308	Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence	20537-20566	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP029972	Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence	6123-6152	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP029967	Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence	28417-28446	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	LT615366	Enterococcus phage VPE25 genome assembly, chromosome: VPE25	14742-14771	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	LT546029	Enterococcus phage VFW genome assembly, chromosome: VFW	14675-14704	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	LT546030	Enterococcus phage VPE25 genome assembly, chromosome: I	14742-14771	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	MT119360	Enterococcus phage nattely, complete genome	14821-14850	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP037431	Lactobacillus plantarum strain EM plasmid pEM2, complete sequence	20908-20937	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP025692	Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence	133-162	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP035559	Lactobacillus plantarum strain SRCM103297 plasmid unnamed3	24727-24756	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP035572	Lactobacillus plantarum strain SRCM103303 plasmid unnamed1	22589-22618	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP035175	Lactobacillus plantarum strain SRCM103426 plasmid unnamed1	87952-87981	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP018327	Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-3, complete sequence	992-1021	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP035116	Lactobacillus plantarum strain SRCM103295 plasmid unnamed3	94597-94626	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP018798	Lactobacillus parabuchneri strain FAM21731 plasmid pFAM21731.2, complete sequence	27103-27132	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP025415	Lactobacillus plantarum strain X7021 plasmid unnamed3, complete sequence	13215-13244	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP021928	Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-2, complete sequence	6938-6967	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP035145	Lactobacillus plantarum strain SRCM103357 plasmid unnamed2	36987-37016	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP050806	Lactobacillus plantarum strain SPC-SNU 72-2 plasmid pLBP752, complete sequence	19494-19523	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP028277	Lactobacillus plantarum strain SRCM100995 plasmid unnamed2, complete sequence	54324-54353	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP013152	Lactobacillus plantarum strain MF1298 plasmid pMF1298-4, complete sequence	22761-22790	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	MT119361	Enterococus phage vipetofem, complete genome	70537-70566	8	0.733
NZ_CP008816_1	1.3\|983096\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983096-983125	30	HG796796	Uncultured bacterium plasmid pRGF00045	2663-2692	8	0.733
NZ_CP008816_1	1.3\|983096\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983096-983125	30	NC_018516	Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence	324412-324441	8	0.733
NZ_CP008816_1	1.3\|983096\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983096-983125	30	NZ_CP009334	Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence	258608-258637	8	0.733
NZ_CP008816_1	1.3\|983096\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983096-983125	30	NZ_CP053970	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence	106037-106066	8	0.733
NZ_CP008816_1	1.3\|983096\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983096-983125	30	NZ_CP053979	Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence	14249-14278	8	0.733
NZ_CP008816_1	1.3\|983096\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983096-983125	30	NZ_CP013277	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence	232571-232600	8	0.733
NZ_CP008816_1	1.3\|983096\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983096-983125	30	NZ_CP039723	Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence	349574-349603	8	0.733
NZ_CP008816_1	1.3\|983096\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983096-983125	30	NZ_CP009348	Bacillus thuringiensis HD1002 plasmid 2, complete sequence	232572-232601	8	0.733
NZ_CP008816_1	1.3\|983096\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983096-983125	30	NZ_CP045024	Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence	232184-232213	8	0.733
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	NZ_CP047122	Lactobacillus hilgardii strain FLUB plasmid unnamed1	39415-39444	9	0.7
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	KM359505	Prochlorococcus phage P-TIM68, complete genome	108590-108619	9	0.7
NZ_CP008816_1	1.1\|982964\|30\|NZ_CP008816\|CRISPRCasFinder,CRT	982964-982993	30	KY971610	Pseudomonas phage PspYZU05, complete genome	121642-121671	9	0.7
NZ_CP008816_1	1.4\|983162\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983162-983191	30	NZ_CP045274	Bacillus megaterium strain FDU301 plasmid pFDU301B, complete sequence	28090-28119	9	0.7
NZ_CP008816_1	1.5\|983228\|30\|NZ_CP008816\|CRISPRCasFinder,CRT,PILER-CR	983228-983257	30	NZ_AP022566	Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence	231607-231636	9	0.7

1. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to MF157411 (Escherichia coli strain EC1000 plasmid pCR2, complete sequence) position: , mismatch: 0, identity: 1.0

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aggggagaaaaagccaaatcaaaaaagttt	Protospacer
******************************

2. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MH375074 (Enterococcus phage LY0323, complete genome) position: , mismatch: 0, identity: 1.0

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtcggacaggtgacgccagcagat	Protospacer
******************************

3. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NC_042127 (Enterococcus phage vB_EfaS_AL2, complete genome) position: , mismatch: 0, identity: 1.0

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtcggacaggtgacgccagcagat	Protospacer
******************************

4. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NC_031260 (Enterococcus phage Ec-ZZ2, complete genome) position: , mismatch: 0, identity: 1.0

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtcggacaggtgacgccagcagat	Protospacer
******************************

5. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to KF733017 (Enterococcus phage IME-EF4, complete genome) position: , mismatch: 0, identity: 1.0

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtcggacaggtgacgccagcagat	Protospacer
******************************

6. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP022485 (Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

7. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgtaaatcacaatcttttgtaagtc	Protospacer
****************.*************

8. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

9. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to CP002493 (Enterococcus faecalis 62 plasmid EF62pB, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

10. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

11. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

12. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

13. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NC_006827 (Enterococcus faecalis plasmid pCF10, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgtaaatcacaatcttttgtaagtc	Protospacer
****************.*************

14. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

15. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP028283 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

16. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP042215 (Enterococcus faecalis strain L15 plasmid pL15-A, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

17. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_MG765452 (Enterococcus faecalis strain E512 plasmid pE512, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

18. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacagtcttttgtaagtc	Protospacer
*******.**********************

19. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to CAJDJX010000002 (Enterococcus phage Q69 genome assembly, contig: phageQ69-genome, whole genome shotgun sequence) position: , mismatch: 1, identity: 0.967

tatggttttgaataaattgtacatcattat	CRISPR spacer
tatggttttgaataaattgcacatcattat	Protospacer
*******************.**********

20. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to CAJDKF010000002 (Enterococcus phage vB_EfaS_159 genome assembly, contig: phage159-genome, whole genome shotgun sequence) position: , mismatch: 1, identity: 0.967

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtaggacaggtgacgccagcagat	Protospacer
******** *********************

21. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP041739 (Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence) position: , mismatch: 2, identity: 0.933

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
tataacgcaaatcacaatcttttgtaagtc	Protospacer
*******.********.*************

22. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MK721199 (Enterococcus phage vB_EfaS_Ef5.1, complete genome) position: , mismatch: 2, identity: 0.933

tatggttttgaataaattgtacatcattat	CRISPR spacer
tatggttttgaatgaattgcacatcattat	Protospacer
*************.*****.**********

23. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MK721190 (Enterococcus phage vB_EfaS_Ef6.4, complete genome) position: , mismatch: 2, identity: 0.933

tatggttttgaataaattgtacatcattat	CRISPR spacer
tgtggttttgaatgaattgtacatcattat	Protospacer
*.***********.****************

24. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MK721200 (Enterococcus phage vB_EfaS_Ef5.3, complete genome) position: , mismatch: 2, identity: 0.933

tatggttttgaataaattgtacatcattat	CRISPR spacer
tatggttttgaatgaattgcacatcattat	Protospacer
*************.*****.**********

25. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NC_031260 (Enterococcus phage Ec-ZZ2, complete genome) position: , mismatch: 2, identity: 0.933

tatggttttgaataaattgtacatcattat	CRISPR spacer
tatggttttgaatgaattgcacatcattat	Protospacer
*************.*****.**********

26. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to KF733017 (Enterococcus phage IME-EF4, complete genome) position: , mismatch: 2, identity: 0.933

tatggttttgaataaattgtacatcattat	CRISPR spacer
tatggttttgaatgaattgcacatcattat	Protospacer
*************.*****.**********

27. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to CAJDKF010000002 (Enterococcus phage vB_EfaS_159 genome assembly, contig: phage159-genome, whole genome shotgun sequence) position: , mismatch: 2, identity: 0.933

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtaggacaggtgacaccagcagat	Protospacer
******** ***********.*********

28. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MT119359 (Enterococcus phage heks, complete genome) position: , mismatch: 2, identity: 0.933

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtcgggcaggtgacaccagcagat	Protospacer
***********.********.*********

29. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to CAJDJX010000002 (Enterococcus phage Q69 genome assembly, contig: phageQ69-genome, whole genome shotgun sequence) position: , mismatch: 2, identity: 0.933

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtaggacaggtgacaccagcagat	Protospacer
******** ***********.*********

30. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MK125140 (Enterococcus phage Nonaheksakonda, complete genome) position: , mismatch: 2, identity: 0.933

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtcgggcaggtgacaccagcagat	Protospacer
***********.********.*********

31. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MK982307 (Enterococcus phage MSF2, complete genome) position: , mismatch: 2, identity: 0.933

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtaggacaggtgacaccagcagat	Protospacer
******** ***********.*********

32. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to CAJDKF010000002 (Enterococcus phage vB_EfaS_159 genome assembly, contig: phage159-genome, whole genome shotgun sequence) position: , mismatch: 3, identity: 0.9

tatggttttgaataaattgtacatcattat	CRISPR spacer
tgtggttttgaatgaattgcacatcattat	Protospacer
*.***********.*****.**********

33. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to KF728385 (Enterococcus phage IME_EF3, complete genome) position: , mismatch: 3, identity: 0.9

tatggttttgaataaattgtacatcattat	CRISPR spacer
tgtggttttgaatgaattgaacatcattat	Protospacer
*.***********.***** **********

34. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to KJ127304 (Enterococcus phage AUEF3, partial genome) position: , mismatch: 3, identity: 0.9

tatggttttgaataaattgtacatcattat	CRISPR spacer
tgtggttttgaatgaattgcacatcattat	Protospacer
*.***********.*****.**********

35. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MK125140 (Enterococcus phage Nonaheksakonda, complete genome) position: , mismatch: 3, identity: 0.9

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtaggacaggtgacaccagcagaa	Protospacer
******** ***********.********

36. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MG264739 (UNVERIFIED: Enterococcus phage phiNASRA1, complete genome) position: , mismatch: 3, identity: 0.9

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
cctgtggtaggacaggtgacaccagcagac	Protospacer
******** ***********.********.

37. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042332 (Bosea sp. F3-2 plasmid pB32-1, complete sequence) position: , mismatch: 5, identity: 0.833

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
catgatgtaggacaggtgacgccagcggat	Protospacer
* **  ** *****************.***

38. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to MK496783 (Capybara microvirus Cap3_SP_410, complete genome) position: , mismatch: 6, identity: 0.8

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
agggcagaaaaagccaaatcaagaattatc	Protospacer
**** *****************.**   *.

39. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to MN693358 (Marine virus AFVG_25M395, complete genome) position: , mismatch: 6, identity: 0.8

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aacgcacaaaaagcccaatcaaaaaagatt	Protospacer
*. * * ******** *********** **

40. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to MN694190 (Marine virus AFVG_250M608, complete genome) position: , mismatch: 6, identity: 0.8

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
tggagtgcgaaagccaaatcaaaaaaggtt	Protospacer
 **.* * .****************** **

41. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MT074134 (Bacteroides phage ARB14, complete genome) position: , mismatch: 6, identity: 0.8

tatggttttgaataaattgtacatcattat	CRISPR spacer
aaaggttttgaataaattgtatatcgaaat	Protospacer
 * ******************.***.  **

42. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MT074143 (Bacteroides phage HNL05, complete genome) position: , mismatch: 6, identity: 0.8

tatggttttgaataaattgtacatcattat	CRISPR spacer
aaaggttttgaataaattgtatatcgaaat	Protospacer
 * ******************.***.  **

43. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MT074135 (Bacteroides phage ARB25, complete genome) position: , mismatch: 6, identity: 0.8

tatggttttgaataaattgtacatcattat	CRISPR spacer
aaaggttttgaataaattgtatatcgaaat	Protospacer
 * ******************.***.  **

44. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to MT074144 (Bacteroides phage HNL35, complete genome) position: , mismatch: 6, identity: 0.8

tatggttttgaataaattgtacatcattat	CRISPR spacer
aaaggttttgaataaattgtatatcgaaat	Protospacer
 * ******************.***.  **

45. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NC_014502 (Gloeothece verrucosa PCC 7822 plasmid Cy782203, complete sequence) position: , mismatch: 7, identity: 0.767

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aatcaacaaaaagccaaaacaaaaaagtta	Protospacer
*.  .* *********** **********

46. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP032754 (Lactobacillus plantarum subsp. argentoratensis strain DSM 16365 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaatttct	Protospacer
*.  ********* ***********  *.*

47. spacer 1.2|983030|30|NZ_CP008816|CRISPRCasFinder,CRT matches to MN694044 (Marine virus AFVG_250M514, complete genome) position: , mismatch: 7, identity: 0.767

tataacgtaaatcacagtcttttgtaagtc	CRISPR spacer
aactgcataaatcacaggcttttgtaagcc	Protospacer
 *. .*.********** **********.*

48. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011146 (Bacillus cereus strain FORC_013 plasmid pFORC13, complete sequence) position: , mismatch: 7, identity: 0.767

tatggttttgaataaattgtacatcattat	CRISPR spacer
aagttttttgaataaaatgtacctcattag	Protospacer
 *   *********** ***** ******

49. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP028270 (Pediococcus pentosaceus strain SRCM102740 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

50. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP028267 (Pediococcus pentosaceus strain SRCM102739 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

51. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP015919 (Pediococcus pentosaceus strain wikim20 plasmid pKPP01, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

52. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP021931 (Lactobacillus plantarum strain TMW 1.1308 plasmid pL11308-1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

53. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP024059 (Lactobacillus plantarum strain KACC 92189 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

54. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP028265 (Pediococcus pentosaceus strain SRCM102738 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

55. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP018326 (Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

56. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP019582 (Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

57. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP035308 (Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

58. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP029972 (Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

59. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP029967 (Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

60. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to LT615366 (Enterococcus phage VPE25 genome assembly, chromosome: VPE25) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

61. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to LT546029 (Enterococcus phage VFW genome assembly, chromosome: VFW) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

62. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to LT546030 (Enterococcus phage VPE25 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

63. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to MT119360 (Enterococcus phage nattely, complete genome) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

64. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP037431 (Lactobacillus plantarum strain EM plasmid pEM2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

65. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP025692 (Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

66. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP035559 (Lactobacillus plantarum strain SRCM103297 plasmid unnamed3) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

67. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP035572 (Lactobacillus plantarum strain SRCM103303 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

68. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP035175 (Lactobacillus plantarum strain SRCM103426 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

69. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP018327 (Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-3, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

70. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP035116 (Lactobacillus plantarum strain SRCM103295 plasmid unnamed3) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

71. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP018798 (Lactobacillus parabuchneri strain FAM21731 plasmid pFAM21731.2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

72. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP025415 (Lactobacillus plantarum strain X7021 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

73. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP021928 (Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

74. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP035145 (Lactobacillus plantarum strain SRCM103357 plasmid unnamed2) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

75. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP050806 (Lactobacillus plantarum strain SPC-SNU 72-2 plasmid pLBP752, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

76. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP028277 (Lactobacillus plantarum strain SRCM100995 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

77. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP013152 (Lactobacillus plantarum strain MF1298 plasmid pMF1298-4, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

78. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to MT119361 (Enterococus phage vipetofem, complete genome) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

79. spacer 1.3|983096|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to HG796796 (Uncultured bacterium plasmid pRGF00045) position: , mismatch: 8, identity: 0.733

attaacgtagttgattcagaaaaaccaagc	CRISPR spacer
attgatgtagttgattcagaaaaagttgag	Protospacer
***.*.****************** . ..

80. spacer 1.3|983096|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NC_018516 (Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence) position: , mismatch: 8, identity: 0.733

attaacgtagttgattcagaaaaaccaagc	CRISPR spacer
gaaaacgtagttgtatcagaaaaacctgga	Protospacer
.  **********  *********** .*

81. spacer 1.3|983096|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009334 (Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.733

attaacgtagttgattcagaaaaaccaagc	CRISPR spacer
gaaaacgtagttgtatcagaaaaacctgga	Protospacer
.  **********  *********** .*

82. spacer 1.3|983096|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053970 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

attaacgtagttgattcagaaaaaccaagc	CRISPR spacer
gaaaacgtagttgtatcagaaaaacctgga	Protospacer
.  **********  *********** .*

83. spacer 1.3|983096|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053979 (Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

attaacgtagttgattcagaaaaaccaagc	CRISPR spacer
gaaaacgtagttgtatcagaaaaacctgga	Protospacer
.  **********  *********** .*

84. spacer 1.3|983096|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013277 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence) position: , mismatch: 8, identity: 0.733

attaacgtagttgattcagaaaaaccaagc	CRISPR spacer
gaaaacgtagttgtatcagaaaaacctgga	Protospacer
.  **********  *********** .*

85. spacer 1.3|983096|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039723 (Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

attaacgtagttgattcagaaaaaccaagc	CRISPR spacer
gaaaacgtagttgtatcagaaaaacctgga	Protospacer
.  **********  *********** .*

86. spacer 1.3|983096|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009348 (Bacillus thuringiensis HD1002 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.733

attaacgtagttgattcagaaaaaccaagc	CRISPR spacer
gaaaacgtagttgtatcagaaaaacctgga	Protospacer
.  **********  *********** .*

87. spacer 1.3|983096|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045024 (Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

attaacgtagttgattcagaaaaaccaagc	CRISPR spacer
gaaaacgtagttgtatcagaaaaacctgga	Protospacer
.  **********  *********** .*

88. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to NZ_CP047122 (Lactobacillus hilgardii strain FLUB plasmid unnamed1) position: , mismatch: 9, identity: 0.7

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
taacatctcaaagccaaatcaaaaaagttt	Protospacer
 .. .    *********************

89. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 9, identity: 0.7

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
caaagagaaaaagcaaaattaaaaaaggaa	Protospacer
 ...********** ****.*******

90. spacer 1.1|982964|30|NZ_CP008816|CRISPRCasFinder,CRT matches to KY971610 (Pseudomonas phage PspYZU05, complete genome) position: , mismatch: 9, identity: 0.7

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
gaaagagaaaaagcaaaatcaaaaacctaa	Protospacer
....********** **********  *

91. spacer 1.4|983162|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045274 (Bacillus megaterium strain FDU301 plasmid pFDU301B, complete sequence) position: , mismatch: 9, identity: 0.7

tatggttttgaataaattgtacatcattat	CRISPR spacer
ataggtttttaataaattgtaaatcaagtg	Protospacer
   ****** *********** ****

92. spacer 1.5|983228|30|NZ_CP008816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022566 (Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence) position: , mismatch: 9, identity: 0.7

cctgtggtcggacaggtgacgccagcagat	CRISPR spacer
agcgtggtcggaaaggtgacgccagtcttc	Protospacer
  .********* ************.   .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

328422 : 342729

Enterococcus_phage(30.0%)

tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002357859.1\|328422_330819_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.7e-19	24.1
WP_002360497.1\|330843_331194_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002393873.1\|331276_331507_+	hypothetical protein	NA	NA	NA	NA
WP_002382232.1\|331566_332052_-	toxin	A0A097BY56	Enterococcus_phage	4.4e-60	70.5
WP_002357856.1\|332086_332569_-	helix-turn-helix transcriptional regulator	R9QTP6	Staphylococcus_phage	1.2e-20	48.6
WP_002392532.1\|332964_333720_+	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	8.7e-31	56.0
WP_002404235.1\|333738_334581_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	3.3e-31	31.0
WP_002357852.1\|334647_335040_+	hypothetical protein	NA	NA	NA	NA
WP_002357851.1\|335059_335467_+	RinA family phage transcriptional activator	NA	NA	NA	NA
WP_002382237.1\|335688_336105_+	hypothetical protein	NA	NA	NA	NA
WP_002381948.1\|336117_336630_+\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	8.8e-35	49.4
WP_002357848.1\|336662_337022_+	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	7.6e-09	32.2
WP_002392533.1\|337114_337408_+	hypothetical protein	NA	NA	NA	NA
WP_002404234.1\|337397_340331_+	membrane protein	W8EBC4	Geobacillus_phage	6.9e-15	41.2
WP_002365553.1\|340332_341259_+\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	9.0e-147	78.6
WP_002357844.1\|341271_342729_+	structural protein	C9E2K6	Enterococcus_phage	9.5e-175	47.7

DBSCAN-SWA_2

784802 : 793446

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002364081.1\|784802_785375_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.2e-25	35.1
WP_002384439.1\|785371_786403_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	1.1e-55	44.4
WP_002384438.1\|786404_787844_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.7e-49	32.3
WP_002414592.1\|787819_790039_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.3e-146	40.1
WP_002364085.1\|790035_790710_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002357271.1\|790710_790962_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002357270.1\|790975_791689_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	4.3e-48	43.0
WP_002384435.1\|791840_792965_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002384434.1\|792957_793446_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.8e-19	42.0

DBSCAN-SWA_3

823915 : 842007

Thermus_phage(25.0%)

protease,transposase,integrase

attL 840205:840229|attR 845271:845295

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002403141.1\|823915_824794_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_077497612.1\|824818_826351_-	M4 family metallopeptidase coccolysin	NA	NA	NA	NA
WP_002384418.1\|826585_827389_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_002403140.1\|827585_828107_-	HD domain-containing protein	NA	NA	NA	NA
WP_002360101.1\|828330_829236_+	polysaccharide deacetylase	NA	NA	NA	NA
WP_002360100.1\|829409_829826_-	hypothetical protein	NA	NA	NA	NA
WP_002297659.1\|830983_832162_-\|integrase	site-specific integrase	S6C485	Thermus_phage	3.4e-29	30.5
WP_002382441.1\|832264_832621_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002360096.1\|832924_833170_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002297668.1\|833163_833565_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_002297670.1\|834132_835968_-	beta-galactosidase	NA	NA	NA	NA
WP_002330923.1\|836139_837402_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002360092.1\|837539_837764_+	hypothetical protein	NA	NA	NA	NA
WP_002298159.1\|837760_837925_+	hypothetical protein	NA	NA	NA	NA
WP_002298157.1\|838018_839311_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	3.9e-31	40.4
WP_002313174.1\|839584_839845_-	hypothetical protein	NA	NA	NA	NA
840205:840229	attL	NA	NA	NA	NA
WP_101495273.1\|840449_841611_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.0e-79	51.3
WP_077497620.1\|841683_841890_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	U5P429	Shigella_phage	2.0e-06	53.3
WP_002383094.1\|841893_842007_+\|transposase	IS3 family transposase	NA	NA	NA	NA
845271:845295	attR	NA	NA	NA	NA

DBSCAN-SWA_4

858015 : 869499

Streptococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002298830.1\|858015_859020_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	1.4e-121	66.3
WP_002384404.1\|859016_861140_-\|transposase	transposase	A0A1S5SF30	Streptococcus_phage	2.4e-174	58.7
WP_002330910.1\|861144_863592_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	76.4
WP_002298826.1\|863578_863968_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	2.5e-42	66.7
WP_002383098.1\|864019_864760_+	hypothetical protein	NA	NA	NA	NA
WP_002360078.1\|864766_865603_-	abortive infection family protein	NA	NA	NA	NA
WP_002298823.1\|865667_866171_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	3.1e-56	61.2
WP_002298822.1\|866183_866405_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.5e-28	87.7
WP_002414793.1\|866801_868052_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	3.0e-113	62.1
WP_002330905.1\|868183_868318_-	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_002360076.1\|868314_869499_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	1.0e-142	62.1

DBSCAN-SWA_5

1072215 : 1091598

Streptococcus_phage(89.47%)

integrase

attL 1071188:1071204|attR 1101375:1101391

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1071188:1071204	attL	NA	NA	NA	NA
WP_001291561.1\|1072215_1073433_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|1073514_1073718_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_000857133.1\|1074178_1074409_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000804885.1\|1074405_1074828_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_001227347.1\|1075332_1075686_+	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000336323.1\|1075745_1075913_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_002414694.1\|1076031_1077951_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A2K5B2A5	Erysipelothrix_phage	0.0e+00	99.7
WP_001814923.1\|1077966_1078083_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224320.1\|1078327_1079263_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	7.7e-170	99.0
WP_000769868.1\|1079259_1080261_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_000804748.1\|1080257_1082435_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000331160.1\|1082437_1084885_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000506270.1\|1084868_1085375_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|1085349_1085847_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|1085963_1086185_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000398284.1\|1086227_1087433_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_000879507.1\|1087455_1087608_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|1087610_1088996_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|1089024_1089411_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|1089426_1089741_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_002387247.1\|1090201_1090555_+	YxeA family protein	NA	NA	NA	NA
WP_002356866.1\|1090593_1091598_-	nucleoid-associated protein	A0A090D855	Clostridium_phage	8.6e-10	22.3
1101375:1101391	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1514156 : 1523896

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002385686.1\|1514156_1516340_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	3.1e-286	66.8
WP_002365065.1\|1516372_1516969_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	2.3e-50	56.1
WP_002362328.1\|1517013_1518132_-	DNA polymerase IV	NA	NA	NA	NA
WP_002365066.1\|1518257_1519016_-	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002356375.1\|1518999_1519662_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.7e-19	31.1
WP_002356373.1\|1519676_1520549_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	6.2e-81	57.6
WP_002356372.1\|1520660_1521008_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	8.1e-16	36.7
WP_002356371.1\|1521000_1521840_-	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002384059.1\|1521956_1522907_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.2e-34	33.0
WP_002356367.1\|1522908_1523238_-	hypothetical protein	NA	NA	NA	NA
WP_002356366.1\|1523257_1523896_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.1e-54	53.8

DBSCAN-SWA_7

1544689 : 1595508

Enterococcus_phage(43.75%)

terminase,protease,portal,integrase,plate,tRNA,holin,tail

attL 1586730:1586744|attR 1591473:1591487

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002362481.1\|1544689_1545400_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_002385677.1\|1545410_1545953_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_002356329.1\|1546040_1546811_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_002356327.1\|1546976_1547552_+	DUF805 domain-containing protein	NA	NA	NA	NA
WP_002399111.1\|1547642_1549208_+	membrane protein	NA	NA	NA	NA
WP_002392337.1\|1549159_1550293_+	DUF4950 domain-containing protein	C9E2L5	Enterococcus_phage	1.0e-19	51.5
WP_002356323.1\|1550552_1551617_-	FUSC family protein	NA	NA	NA	NA
WP_002389274.1\|1551872_1552124_-	hypothetical protein	NA	NA	NA	NA
WP_002414603.1\|1552916_1553726_-	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_002404583.1\|1554121_1555360_-	LysM peptidoglycan-binding domain-containing protein	A0A0S2MYF3	Enterococcus_phage	1.2e-175	74.5
WP_002369080.1\|1555364_1555568_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	2.6e-30	100.0
WP_040118571.1\|1555836_1555974_-	XkdX family protein	NA	NA	NA	NA
WP_002414601.1\|1556358_1556883_-	hypothetical protein	NA	NA	NA	NA
WP_002369975.1\|1556882_1557200_-	hypothetical protein	NA	NA	NA	NA
WP_002414600.1\|1557192_1557510_-	hypothetical protein	NA	NA	NA	NA
WP_010784633.1\|1557502_1558411_-\|plate	phage baseplate upper protein	Q9AYV5	Lactococcus_phage	1.4e-11	25.7
WP_025193066.1\|1558425_1561140_-	peptidoglycan DD-metalloendopeptidase family protein	Q9AZX5	Lactococcus_phage	6.1e-175	38.2
WP_002414530.1\|1561121_1561856_-	hypothetical protein	B8R658	Lactobacillus_phage	1.6e-16	32.5
WP_025193156.1\|1561845_1564743_-	tape measure protein	D7RWD8	Brochothrix_phage	1.2e-80	43.6
WP_002364485.1\|1564991_1565345_-	hypothetical protein	A0A2H4J3G5	uncultured_Caudovirales_phage	5.9e-06	30.5
WP_002414527.1\|1565397_1566240_-\|tail	tail protein	A5GYM0	Lactococcus_phage	5.5e-10	53.9
WP_002414526.1\|1566240_1566615_-	hypothetical protein	NA	NA	NA	NA
WP_002402415.1\|1566618_1567017_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_002414525.1\|1567009_1567387_-	hypothetical protein	NA	NA	NA	NA
WP_002395886.1\|1567383_1567728_-	hypothetical protein	NA	NA	NA	NA
WP_002414524.1\|1567736_1567973_-	hypothetical protein	NA	NA	NA	NA
WP_002414522.1\|1567996_1568899_-	DUF5309 family protein	NA	NA	NA	NA
WP_002414521.1\|1568912_1569539_-	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_002414520.1\|1569756_1570077_-	hypothetical protein	NA	NA	NA	NA
WP_002414519.1\|1570133_1570364_-	hypothetical protein	NA	NA	NA	NA
WP_002414518.1\|1570364_1572149_-	hypothetical protein	NA	NA	NA	NA
WP_002414517.1\|1572123_1573599_-\|portal	phage portal protein	A0A0A7AQF2	Bacillus_phage	2.2e-30	25.5
WP_025193069.1\|1573611_1574886_-\|terminase	PBSX family phage terminase large subunit	A0A1B1UZZ1	Enterococcus_phage	7.9e-234	94.7
WP_002414515.1\|1574875_1575337_-\|terminase	terminase small subunit	D7RWC4	Brochothrix_phage	4.8e-24	46.7
WP_002369895.1\|1575714_1576575_-	hypothetical protein	A0A0S2MYE5	Enterococcus_phage	1.2e-113	99.5
WP_002357362.1\|1577432_1577849_-	autolysin	D2IZL7	Enterococcus_phage	1.7e-68	99.3
WP_002357361.1\|1578238_1578487_-	hypothetical protein	D2IZL5	Enterococcus_phage	4.5e-29	87.9
WP_010784645.1\|1578621_1579137_-	DUF1642 domain-containing protein	D2IYV1	Enterococcus_phage	1.1e-66	78.8
WP_002414886.1\|1579270_1579603_-	hypothetical protein	D2IYU9	Enterococcus_phage	6.7e-36	90.2
WP_010784646.1\|1579603_1579984_-	hypothetical protein	D2IZL0	Enterococcus_phage	5.3e-37	67.2
WP_025193072.1\|1579980_1580217_-	hypothetical protein	NA	NA	NA	NA
WP_010784647.1\|1580224_1581274_-	DNA (cytosine-5-)-methyltransferase	A0A141E1L1	Streptococcus_phage	4.6e-131	64.6
WP_025191024.1\|1581326_1581533_-	hypothetical protein	A0A1B1V001	Enterococcus_phage	5.6e-25	98.4
WP_002414634.1\|1581552_1581882_-	hypothetical protein	NA	NA	NA	NA
WP_002414633.1\|1581893_1582421_-	single-stranded DNA-binding protein	A0A097PAQ3	Streptococcus_pyogenes_phage	2.0e-42	56.0
WP_002365159.1\|1582425_1583277_-	helix-turn-helix domain-containing protein	U5U793	Lactobacillus_phage	3.1e-24	29.3
WP_002414632.1\|1583280_1583922_-	hypothetical protein	U5U4M2	Lactobacillus_phage	3.7e-30	35.1
WP_002365157.1\|1583926_1584943_-	AAA family ATPase	A0A0S2SY47	Bacillus_phage	9.2e-60	43.2
WP_002381628.1\|1584954_1585434_-	siphovirus Gp157 family protein	E5DV79	Deep-sea_thermophilic_phage	1.2e-33	48.4
WP_002364665.1\|1585923_1586109_-	hypothetical protein	D2IZW5	Enterococcus_phage	3.2e-19	86.7
WP_002414624.1\|1586119_1586830_-	phage regulatory protein	D2IYT0	Enterococcus_phage	7.5e-117	90.6
1586730:1586744	attL	NA	NA	NA	NA
WP_002414623.1\|1586911_1587181_-	hypothetical protein	NA	NA	NA	NA
WP_002414622.1\|1587195_1587390_-	helix-turn-helix transcriptional regulator	A0A1S5SDR1	Streptococcus_phage	8.5e-07	37.9
WP_002401993.1\|1587634_1587982_+	helix-turn-helix transcriptional regulator	A0A1S5SDR1	Streptococcus_phage	4.9e-21	45.2
WP_002401992.1\|1588010_1588421_+	ImmA/IrrE family metallo-endopeptidase	D2IZV8	Enterococcus_phage	2.6e-05	31.5
WP_002414620.1\|1589256_1589586_+	hypothetical protein	NA	NA	NA	NA
WP_033072557.1\|1589708_1590890_+\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	1.9e-48	31.8
WP_002356321.1\|1590993_1591143_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_002362353.1\|1593570_1595508_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	2.3e-112	36.3
1591473:1591487	attR	NA	NA	NA	NA

DBSCAN-SWA_8

1659823 : 1695776

Enterococcus_phage(37.5%)

head,terminase,protease,portal,plate,holin,tail,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355121.1\|1659823_1660024_-	cold-shock protein	Q9AZD3	Lactococcus_phage	5.3e-20	69.2
WP_002369969.1\|1660177_1660378_-	DNA repair protein	NA	NA	NA	NA
WP_002369970.1\|1660408_1661494_-	N-acetylmuramoyl-L-alanine amidase	A0A1G5SA77	Enterococcus_phage	1.7e-88	50.7
WP_002369080.1\|1661498_1661702_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	2.6e-30	100.0
WP_002367247.1\|1661704_1661938_-\|holin	holin	D2J075	Enterococcus_phage	7.0e-24	70.2
WP_002369972.1\|1661971_1662109_-	XkdX family protein	NA	NA	NA	NA
WP_002414602.1\|1662108_1662483_-	hypothetical protein	NA	NA	NA	NA
WP_002414601.1\|1662497_1663022_-	hypothetical protein	NA	NA	NA	NA
WP_002369975.1\|1663021_1663339_-	hypothetical protein	NA	NA	NA	NA
WP_002414600.1\|1663331_1663649_-	hypothetical protein	NA	NA	NA	NA
WP_033072562.1\|1663641_1664550_-\|plate	phage baseplate upper protein	Q9AYV5	Lactococcus_phage	1.4e-11	26.2
WP_002414606.1\|1664568_1667367_-	CHAP domain-containing protein	D7RWE0	Brochothrix_phage	4.5e-64	39.0
WP_025186801.1\|1667363_1668068_-\|tail	phage tail protein	NA	NA	NA	NA
WP_048943158.1\|1668073_1670389_-\|tail	phage tail tape measure protein	A0A0U4IIN6	Exiguobacterium_phage	1.0e-85	52.9
WP_002369981.1\|1670637_1671066_-	hypothetical protein	A0A1B1P7Q6	Bacillus_phage	1.3e-28	47.7
WP_025186802.1\|1671068_1671725_-	hypothetical protein	A0A2H4JGN2	uncultured_Caudovirales_phage	5.4e-45	45.8
WP_002369983.1\|1671721_1672078_-	HK97 gp10 family phage protein	A0A1B2APW9	Phage_Wrath	2.6e-17	42.6
WP_002369984.1\|1672070_1672403_-	hypothetical protein	A0A2H4JFJ3	uncultured_Caudovirales_phage	4.8e-18	41.0
WP_002365100.1\|1672392_1672719_-\|head	phage head closure protein	A0A0N7IRA3	Lactobacillus_phage	1.7e-20	52.4
WP_002385660.1\|1672696_1672987_-\|head,tail	phage gp6-like head-tail connector protein	A0A1B1P7M9	Bacillus_phage	7.4e-23	64.3
WP_002369987.1\|1672979_1674344_-\|capsid	phage major capsid protein	A0A1B2APY9	Phage_Wrath	2.2e-125	67.6
WP_002393805.1\|1674356_1674929_-\|head,protease	HK97 family phage prohead protease	A0A2H4J6Z9	uncultured_Caudovirales_phage	6.5e-63	62.4
WP_002388450.1\|1674900_1676127_-\|portal	phage portal protein	A0A2H4J9C7	uncultured_Caudovirales_phage	4.1e-147	66.3
WP_002414607.1\|1676145_1677873_-\|terminase	terminase large subunit	A0A2H4JDG5	uncultured_Caudovirales_phage	4.6e-253	70.4
WP_002365107.1\|1677869_1678322_-	hypothetical protein	A0A2H4JFK0	uncultured_Caudovirales_phage	8.0e-48	68.5
WP_002369992.1\|1678432_1678807_-	HNH endonuclease	A0A1B0T6C5	Bacillus_phage	6.2e-46	69.9
WP_002369993.1\|1678806_1679214_-	hypothetical protein	A0A1B1P7N8	Bacillus_phage	3.4e-13	39.4
WP_002406142.1\|1679794_1680124_-	hypothetical protein	A0A1B1P9Z3	Enterococcus_phage	4.8e-10	46.6
WP_002357362.1\|1680331_1680748_-	autolysin	D2IZL7	Enterococcus_phage	1.7e-68	99.3
WP_002380820.1\|1681091_1681292_-	hypothetical protein	D2IYV2	Enterococcus_phage	1.8e-31	100.0
WP_033072561.1\|1681295_1681820_-	DUF1642 domain-containing protein	D2IZL3	Enterococcus_phage	2.0e-42	54.5
WP_002414787.1\|1681833_1682112_-	hypothetical protein	A0A0S2MYC7	Enterococcus_phage	6.9e-42	94.6
WP_002414786.1\|1682112_1682442_-	hypothetical protein	S6CQM6	Streptococcus_phage	2.5e-35	71.0
WP_010784247.1\|1682438_1682909_-	hypothetical protein	A0A097BY92	Enterococcus_phage	3.4e-41	66.2
WP_002370000.1\|1682931_1683372_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_002370001.1\|1683368_1684685_-	N-6 DNA methylase	A0A1X9I6H1	Streptococcus_phage	6.5e-90	44.8
WP_033072560.1\|1684740_1684947_-	hypothetical protein	A0A1B1V001	Enterococcus_phage	1.6e-24	95.2
WP_002370003.1\|1684962_1685568_-	hypothetical protein	NA	NA	NA	NA
WP_002370004.1\|1685579_1686044_-	DUF1064 domain-containing protein	A0A1I9KKZ1	Lactobacillus_phage	7.0e-31	48.3
WP_002365122.1\|1686192_1686462_-	hypothetical protein	NA	NA	NA	NA
WP_002414890.1\|1686600_1687452_-	ATP-binding protein	U5PVD6	Bacillus_phage	1.9e-21	32.9
WP_002414891.1\|1687463_1688219_-	DnaD domain protein	Q6J1V6	Lactobacillus_phage	2.2e-34	59.8
WP_002370007.1\|1688233_1689049_-	hypothetical protein	J7KGZ1	Streptococcus_phage	5.7e-60	50.2
WP_002370008.1\|1689011_1689983_-	recombinase RecT	A0A1S5SAA8	Streptococcus_phage	5.7e-59	45.9
WP_002393052.1\|1690033_1690288_+	hypothetical protein	NA	NA	NA	NA
WP_002370011.1\|1690262_1690481_-	hypothetical protein	NA	NA	NA	NA
WP_002370012.1\|1690584_1690809_-	hypothetical protein	D2IZX4	Enterococcus_phage	4.9e-22	67.1
WP_002414895.1\|1690805_1691105_-	hypothetical protein	NA	NA	NA	NA
WP_002370016.1\|1691191_1691608_-	hypothetical protein	NA	NA	NA	NA
WP_002364354.1\|1691955_1692132_-	helix-turn-helix transcriptional regulator	D2IZW2	Enterococcus_phage	1.7e-14	65.5
WP_002370020.1\|1692451_1692784_+	helix-turn-helix transcriptional regulator	D2IZV9	Enterococcus_phage	3.0e-28	55.5
WP_002370021.1\|1692801_1693146_+	ImmA/IrrE family metallo-endopeptidase	A0A097QQ08	Enterococcus_phage	2.6e-43	74.6
WP_002370022.1\|1693175_1693574_+	hypothetical protein	NA	NA	NA	NA
WP_002370023.1\|1693591_1694314_+	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	4.1e-22	48.4
WP_002370024.1\|1694408_1695776_+	recombinase family protein	D2IZV7	Enterococcus_phage	3.9e-255	97.8

DBSCAN-SWA_9

1951463 : 2006399

Streptococcus_phage(25.0%)

integrase,tRNA,transposase,holin

attL 1975093:1975109|attR 2015545:2015561

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000221326.1\|1951463_1952423_+\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
WP_002392705.1\|1952709_1953723_-	alpha/beta hydrolase	A0A0G2YDK2	Acanthamoeba_polyphaga_mimivirus	3.9e-10	22.6
WP_002404002.1\|1953877_1954423_+	cysteine hydrolase	NA	NA	NA	NA
WP_002354830.1\|1954634_1955318_-\|holin	antiholin-like protein LrgB	NA	NA	NA	NA
WP_002354829.1\|1955314_1955734_-\|holin	antiholin-like murein hydrolase modulator LrgA	NA	NA	NA	NA
WP_002354828.1\|1955885_1956614_-	response regulator	NA	NA	NA	NA
WP_002354827.1\|1956594_1958364_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	4.2e-60	28.5
WP_002354826.1\|1958455_1959274_-	membrane protein	NA	NA	NA	NA
WP_002354825.1\|1959286_1959958_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_002354824.1\|1959954_1960677_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	5.6e-19	27.5
WP_002392708.1\|1961038_1961437_-	OsmC family protein	NA	NA	NA	NA
WP_002354822.1\|1961637_1961907_+	30S ribosomal protein S14	NA	NA	NA	NA
WP_002354818.1\|1962017_1962167_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_002404001.1\|1962182_1963157_+	GTP-binding protein	NA	NA	NA	NA
WP_002383181.1\|1963190_1963313_+	putative metal homeostasis protein	NA	NA	NA	NA
WP_002404000.1\|1963333_1964869_+	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_002413934.1\|1964926_1965901_-\|tRNA	tRNA-dihydrouridine synthase	NA	NA	NA	NA
WP_002354811.1\|1966088_1966859_-	ABC transporter permease	NA	NA	NA	NA
WP_002354809.1\|1966851_1967787_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.4e-22	29.4
WP_002354802.1\|1968044_1968464_+	PTS mannose transporter subunit IIA	NA	NA	NA	NA
WP_002354800.1\|1968476_1968968_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002365419.1\|1968984_1969800_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_010784810.1\|1969796_1970624_+	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_002381047.1\|1970771_1973291_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_002403998.1\|1973345_1974932_-	CHAP domain-containing protein	NA	NA	NA	NA
1975093:1975109	attL	NA	NA	NA	NA
WP_002354788.1\|1976077_1976638_-	hypothetical protein	NA	NA	NA	NA
WP_002372037.1\|1980539_1980947_-	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	3.6e-31	48.9
WP_002372035.1\|1981304_1981664_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002372033.1\|1981660_1983778_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.7e-245	64.6
WP_002403997.1\|1983998_1984811_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002403996.1\|1984972_1986229_+	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.0e-48	30.8
WP_002403995.1\|1986318_1986516_+	hypothetical protein	NA	NA	NA	NA
WP_002403994.1\|1986621_1987671_+\|integrase	site-specific integrase	Q4ZC42	Staphylococcus_virus	7.4e-20	27.6
WP_002354786.1\|1987727_1988120_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_002365424.1\|1988133_1988577_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_002354782.1\|1988798_1989266_-	DNA starvation/stationary phase protection protein	C1KFH1	Lactobacillus_virus	1.0e-05	25.9
WP_002354781.1\|1989394_1990114_-	DUF5105 domain-containing protein	NA	NA	NA	NA
WP_002354779.1\|1990197_1991718_-	gluconokinase	NA	NA	NA	NA
WP_002354778.1\|1991826_1992519_+	prepilin peptidase	NA	NA	NA	NA
WP_002354777.1\|1992567_1996221_-	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	1.4e-65	24.8
WP_002389470.1\|1996387_2000002_-	DNA-directed RNA polymerase subunit beta	A0A1B1ISA9	uncultured_Mediterranean_phage	2.0e-48	24.5
WP_002354774.1\|2000372_2000714_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A1S5SAB3	Streptococcus_phage	5.5e-17	42.5
WP_002354773.1\|2000713_2000944_-	hypothetical protein	NA	NA	NA	NA
WP_002354768.1\|2001118_2001334_-	DNA-binding protein	NA	NA	NA	NA
WP_002354765.1\|2001472_2002465_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_002354763.1\|2002728_2003358_-	chitin-binding protein	NA	NA	NA	NA
WP_002381036.1\|2004050_2005667_+	phosphatase PAP2/LCP family protein	NA	NA	NA	NA
WP_002392818.1\|2005996_2006140_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_073340360.1\|2006258_2006399_+\|holin	putative holin-like toxin	NA	NA	NA	NA
2015545:2015561	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2512845 : 2567409

Bacillus_phage(27.27%)

tRNA,transposase,integrase

attL 2517040:2517065|attR 2567339:2567364

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355365.1\|2512845_2514015_-\|integrase	site-specific integrase	A0A1B0T6A8	Bacillus_phage	3.6e-31	28.9
WP_002355366.1\|2514058_2514289_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
2517040:2517065	attL	NA	NA	NA	NA
WP_002355369.1\|2517317_2518355_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002335374.1\|2518380_2519319_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_002355370.1\|2519843_2520443_+\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	2.5e-28	35.6
WP_002294574.1\|2522174_2522630_+	copper-responsive transcriptional repressor TcrY	NA	NA	NA	NA
WP_002335389.1\|2525184_2525391_+	copper chaperone TcrZ	NA	NA	NA	NA
WP_010784692.1\|2525529_2527602_+	copper-translocating P-type ATPase TcrB	E4ZFI9	Streptococcus_phage	2.2e-60	29.4
WP_000653331.1\|2528124_2531097_-\|transposase	Tn3 family transposase	A0A125RQ78	Bacillus_phage	3.6e-197	36.4
WP_000238804.1\|2531227_2531833_+	recombinase family protein	A0A1V0E035	Clostridioides_phage	1.3e-21	34.2
WP_010784694.1\|2531836_2532202_-	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_010783490.1\|2532179_2532764_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.0e-42	52.2
WP_002414917.1\|2533007_2533496_+\|tRNA	prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
WP_002392382.1\|2534885_2536094_+	YSIRK-targeted surface antigen transcriptional regulator	NA	NA	NA	NA
WP_002358522.1\|2536223_2536640_+	hypothetical protein	NA	NA	NA	NA
WP_002384835.1\|2536864_2537602_+	hypothetical protein	NA	NA	NA	NA
WP_033072569.1\|2537647_2538139_-	recombinase family protein	A0A1V0E035	Clostridioides_phage	1.3e-11	37.2
WP_102882804.1\|2538255_2538549_+	recombinase family protein	NA	NA	NA	NA
WP_100815088.1\|2538561_2538768_+	hypothetical protein	NA	NA	NA	NA
WP_002363071.1\|2538847_2539666_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_002363072.1\|2539821_2540529_+	N-acetylmannosamine-6-phosphate 2-epimerase	NA	NA	NA	NA
WP_002363073.1\|2540521_2542024_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_002358535.1\|2542034_2542517_+	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_002358536.1\|2543149_2543914_-	YibE/F family protein	NA	NA	NA	NA
WP_002363074.1\|2543900_2544965_-	YibE/F family protein	NA	NA	NA	NA
WP_002382844.1\|2545497_2545875_+	hypothetical protein	NA	NA	NA	NA
WP_002363076.1\|2545926_2546331_+	NusG domain II-containing protein	NA	NA	NA	NA
WP_002363077.1\|2546524_2547595_+	ammonium transporter	NA	NA	NA	NA
WP_002363078.1\|2547697_2548831_+	NAD(P)-binding domain-containing protein	V9VEY6	Lactococcus_phage	2.2e-06	26.7
WP_002370911.1\|2549899_2550211_-\|transposase	IS3 family transposase	A0A0N9SIX5	Staphylococcus_phage	1.6e-23	65.6
WP_002367939.1\|2550316_2550592_-\|transposase	transposase	A0A0N9S8A3	Staphylococcus_phage	1.1e-10	40.9
WP_002358549.1\|2551100_2552267_-	ROK family transcriptional regulator	NA	NA	NA	NA
WP_002384845.1\|2552623_2554699_+	family 31 glucosidase	NA	NA	NA	NA
WP_002358551.1\|2554698_2555484_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002358552.1\|2555476_2556289_+	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_002363085.1\|2556313_2556796_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002358554.1\|2556807_2557215_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002364888.1\|2557319_2558627_+	xylose isomerase	NA	NA	NA	NA
WP_002363087.1\|2558688_2560179_+	xylulokinase	NA	NA	NA	NA
WP_002364887.1\|2562370_2565403_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	2.6e-17	23.2
WP_002367943.1\|2565592_2566177_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_002364885.1\|2566173_2567409_+\|transposase	IS256 family transposase	NA	NA	NA	NA
2567339:2567364	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP008816

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection