CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP008711	Burkholderia mallei strain 6 chromosome 1, complete sequence	1 crisprs	cas3,DEDDh,csa3,DinG	1	1	7	0
NZ_CP008710	Burkholderia mallei strain 6 chromosome 2, complete sequence	2 crisprs	DinG,csa3,cas3	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP008711_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008711_1

3321312-3321476

Orphan

Consensus_repeat	Method
GCGTCTCGCGTCTCGCGTCTCGCGT	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP008711_1

>merge|NZ_CP008711|1|3321312-3321476|CRISPRCasFinder
GCGTTCGTCGTCTGTCGTCTGTCGTCTGTCGTTCGTCGTTCCGAACACTGCGCTCTGCGTTGTGCGTCGTGCGTCTCGCGCTCTGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGT

>NZ_CP008711|1|1|3321312-3321476|CRISPRCasFinder
GCGTTCGTCGTCTGTCGTCTGTCGT	CTGTCGTTCGTCGTTCCGAACACTGCGCTCT
GCGTTGTGCGTCGTGCGTCTCGCGC	TCTGCGTCTCGCGTCTC
GCGTCTCGCGTCTCGCGTCTCGCGT	CTCGCGTCTCGCGTCTC
GCGTCTCGCGTCTCGCGTCTCGCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008711.1\|WP_004195345.1\|3314270_3315866_+\|cytochrome-d-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|185052
NZ_CP008711.1\|WP_004195344.1\|3315903_3317040_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|129307
NZ_CP008711.1\|WP_004195339.1\|3321696_3323463_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|182338
NZ_CP008711.1\|WP_004194381.1\|3312304_3313525_-\|ISL3-like-element-ISBma1-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP008711.1\|WP_004195331.1\|3333103_3334204_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008711.1\|WP_004553812.1\|3307097_3307499_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008711.1\|WP_004195330.1\|3334259_3334508_+\|acyl-carrier-protein	unknown	unknown	unknown
NZ_CP008711.1\|WP_024900792.1\|3323575_3326170_-\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP008711.1\|WP_004195342.1\|3318147_3318327_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008711.1\|WP_004200179.1\|3331256_3333023_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341254
NZ_CP008711.1\|WP_004202961.1\|3318537_3321039_+\|family-20-glycosylhydrolase	unknown	unknown	gnl\|CDD\|119337
NZ_CP008711.1\|WP_004185211.1\|3334540_3335428_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008711.1\|WP_004195334.1\|3329899_3330823_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176106
NZ_CP008711.1\|WP_004550904.1\|3317130_3317229_+\|cytochrome-bd-I-oxidase-subunit-CydX	unknown	unknown	gnl\|CDD\|369733
NZ_CP008711.1\|WP_004195347.1\|3313996_3314281_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008711.1\|WP_004195337.1\|3326227_3327235_-\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|225132
NZ_CP008711.1\|WP_004198297.1\|3308282_3310166_+\|gamma-glutamyltransferase	unknown	unknown	gnl\|CDD\|223482
NZ_CP008711.1\|WP_041283566.1\|3310749_3312213_+\|IS1182-like-element-ISBma2-family-transposase	unknown	unknown	gnl\|CDD\|372705
NZ_CP008711.1\|WP_004195336.1\|3327227_3328331_-\|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl\|CDD\|238434
NZ_CP008711.1\|WP_004195335.1\|3328429_3329164_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099

Protein	Function_ID	Function_description	E-value
NZ_CP008711.1\|WP_004195345.1\|3314270_3315866_+\|cytochrome-d-ubiquinol-oxidase-subunit-I	gnl\|CDD\|185052	PRK15097, PRK15097, cytochrome bd-I ubiquinol oxidase subunit CydA.	0
NZ_CP008711.1\|WP_004195344.1\|3315903_3317040_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|129307	TIGR00203, ubiquinol_oxidase_subunit_2, cytochrome d oxidase, subunit II (cydB). part of a two component cytochrome D terminal complex. Terminal reaction in the aerobic respiratory chain. [Energy metabolism, Electron transport].	3.31028e-147
NZ_CP008711.1\|WP_004195339.1\|3321696_3323463_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|182338	PRK10255, PRK10255, PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional.	0
NZ_CP008711.1\|WP_004194381.1\|3312304_3313525_-\|ISL3-like-element-ISBma1-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.12039e-90
NZ_CP008711.1\|WP_024900792.1\|3323575_3326170_-\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP008711.1\|WP_004200179.1\|3331256_3333023_+\|AMP-binding-protein	gnl\|CDD\|341254	cd05931, FAAL, Fatty acyl-AMP ligase (FAAL). FAAL belongs to the class I adenylate forming enzyme family and is homologous to fatty acyl-coenzyme A (CoA) ligases (FACLs). However, FAALs produce only the acyl adenylate and are unable to perform the thioester-forming reaction, while FACLs perform a two-step catalytic reaction; AMP ligation followed by CoA ligation using ATP and CoA as cofactors. FAALs have insertion motifs between the N-terminal and C-terminal subdomains that distinguish them from the FACLs. This insertion motif precludes the binding of CoA, thus preventing CoA ligation. It has been suggested that the acyl adenylates serve as substrates for multifunctional polyketide synthases to permit synthesis of complex lipids such as phthiocerol dimycocerosate, sulfolipids, mycolic acids, and mycobactin.	2.96953e-143
NZ_CP008711.1\|WP_004202961.1\|3318537_3321039_+\|family-20-glycosylhydrolase	gnl\|CDD\|119337	cd06569, GH20_Sm-chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NZ_CP008711.1\|WP_004195334.1\|3329899_3330823_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.03531e-56
NZ_CP008711.1\|WP_004550904.1\|3317130_3317229_+\|cytochrome-bd-I-oxidase-subunit-CydX	gnl\|CDD\|369733	pfam08173, YbgT_YccB, Membrane bound YbgT-like protein. This family contains a set of membrane proteins, typically 33 amino acids long. The family has no known function, but the protein is found in the operon CydAB in E. coli. Members have a consensus motif (MWYFXW) which is rich in aromatic residues. The protein forms a single membrane-spanning helix. This family seems to be restricted to Proteobacteria.	3.71358e-08
NZ_CP008711.1\|WP_004195337.1\|3326227_3327235_-\|SIS-domain-containing-protein	gnl\|CDD\|225132	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane].	3.14814e-93
NZ_CP008711.1\|WP_004198297.1\|3308282_3310166_+\|gamma-glutamyltransferase	gnl\|CDD\|223482	COG0405, Ggt, Gamma-glutamyltransferase [Amino acid transport and metabolism].	0
NZ_CP008711.1\|WP_041283566.1\|3310749_3312213_+\|IS1182-like-element-ISBma2-family-transposase	gnl\|CDD\|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	3.85031e-38
NZ_CP008711.1\|WP_004195336.1\|3327227_3328331_-\|N-acetylglucosamine-6-phosphate-deacetylase	gnl\|CDD\|238434	cd00854, NagA, N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.	1.64789e-149
NZ_CP008711.1\|WP_004195335.1\|3328429_3329164_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.51625e-74

>NZ_CP008711.1|WP_004202961.1|3318537_3321039_+|family-20-glycosylhydrolase
MNRISHSLCAALLAAATLLPTASRAQLPARPTAGAGAPATAAPVRPASTPAELAARLANGLAVRVAVDNNHAASAGVPCADLGADWASCATGRLILQNRGHSPLTDGGWKLYLHSIRRLLRIDRPGFTLRHLTGDLYELTPQPGTVRLAQGERIELPFVAEYWLRRYSDVTPRPYVVVDGAAPAVLRYDDTDDELRYVETLPADAQNNSPGNAPPAAAQPVANRALPSVKRQRALPGALDLRGVELTLPELPSAQVAALRERAGTLGLDGARVPVWGVVAPRRLPADIAVPGGYRLAIGPRGAFIEGADRAGLYYGVQTLFSLVPAGGATVPAMLIEDAPRFTHRGMHVDLARNFKPPATLRRLIDQMSAYKLNRLHLHLSDDEGWRIEIPGLPELTDVGARRCHDPSETRCLLPQLGSGPDDRSGGGYLTRDDYVALLRYAAERFVEVIPEIDMPAHSRAAVVSMEARYRRLHAAGREREANAYRLLDAQDTSNLLTVQFYDRRSDLNPCMPGALNFASKVIREIASMHADAQAPLRIWHFGGDEAKNILLGAGFQPLDGADPGKGRVDLAAQDKPWARSPACTALLRRGEIKSIDELPTRFAKQVSAIVNANGIGTMAAWQDGIKHASGPREFSTRHVMVSLWDTIFWGASDSARDLSAKGYRTVLALPDYLYFDFPYTRNPRERGYYWGSQATDEYKVFSLAPENLPQNAEVFGDRDGNPFEVTSAGAAPSIEGIQGQAWGEVMRNGQLLEYMVYPRLLALAERAWHKADWELPYAAGVRYKLGDTHHVDTAALERDWAGFATVLKQRELPKLERADIGYRKPTFTLTGE
>NZ_CP008711.1|WP_004195342.1|3318147_3318327_+|hypothetical-protein
MHADTPAATRAEIPIETPIDMSAAAPADIRFDARRAAAPKASSAITTAVAPATAARRRR
>NZ_CP008711.1|WP_004550904.1|3317130_3317229_+|cytochrome-bd-I-oxidase-subunit-CydX
MWYFSWILGIGVALAFGIINAMWLEARQKRDA
>NZ_CP008711.1|WP_004195344.1|3315903_3317040_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MDYATLKVIWWLLVGILLIGFALTDGFDMGVAALLPFLGKTDDERRIIVNTVGATWEGNQVWLITAGGAMFAAWPLVYAASFSGFYFAMLLVLFALFFRPVGFDYRSKRDDPRWRTSWDWALFAGGFVPALVFGVAFGNLLQGVPFAFDTDMRVTYHGSFWALLNPFALLCGLVSLTMLVAHGAAFVKMKTDGAIARRASIALRVSSLVAVVLFVLAGALIASFIGGFQITQAAPLDTVANPLLKQASAAPGLWLVNYGLYPWMIAAPAVGIAGGVLAMLLAGSKREKTAFICTGLMITGVILTAGFSMFPFIMPSSLDPKSSLTVWDSTSSQLTLEVMLVAVIVFLPIILLYTGWVYRVLRGKVTPRVLDENRHSMY
>NZ_CP008711.1|WP_004195345.1|3314270_3315866_+|cytochrome-d-ubiquinol-oxidase-subunit-I
MISSEVVDLSRLQFGITALYHFLFVPLTLGMSWLLVIMEAVYVMTGKQVYKDMTQFWGKLFGINFAMGVTTGITLEFQFGTNWSYYSHYVGDIFGVPLAVEGLMAFFLESTFVGLFFFGWNRLSKVQHLVVTFLVALGSNLSALWILVANGWMNNPVGAEFNYQTMRMELANLFDVLFNPVAQVKFVHTVSAGYVTAAMFVLGVSAWYLLKKRDVDFALRSFAIAAGFGLASTLCVIVLGDESGYTTGEVQKMKLAAIESEWETQPAPASFTLIGLPNQEAERTDYAIKIPYALGLIATRSVSEPVIGLRELAKRSEEHIQSGMIAYGALQKLKAGDTSAETKATFDQHKQYLGYGLMLKQFTQNVTDATPDQIKAAAKQTIPPVAPVFFSFRIMVFLGFLFLATFIAAFWFCARRQLLQDNRRWFLRYAVWAIPLPWLAAEFGWVVAEVGRQPWTIAGILPTHLSASSLTATDLYLSLAGFIVFYTALFIIEITLMFKYARLGPSSLHTGRYHHEQAGRPLEKAVAGTAA
>NZ_CP008711.1|WP_004195347.1|3313996_3314281_+|hypothetical-protein
MALTLINKKASPDGTPPARPAGWRDRAAAWARGPTLARDISIVLAFKLVLLIALKYAFFNHPQAAHMSLPPAVVAAQLLSATPSAPTEGDRHDK
>NZ_CP008711.1|WP_004194381.1|3312304_3313525_-|ISL3-like-element-ISBma1-family-transposase
MLDRKALQALGCWTGYRLERVEWPQGDSRTLSLYLKPVSQIMYCEQCGARCQQIHETTVRRVRDLPLFEYRVMLHVPRRRVWCERCGAARLEKLDWLGRYQRVTQRFAKACEKLLQAASVQAVAAFYDLGWHTVKSIDKMRLRARVAEPDWSTIRYLAMDEFALHKGHRYATVVVDPIGRQVLWVGPGRSRETARAFFEQLPEGVAERIEAVAIDMTTAYELEIKEQCPQAEIVFDLYHVVAKYGREVIDRVRVDQANQLRHDKPARKVLKSSRWLLLRNRHNLKPEQAVHLKELLAANQSLLCVYVLRDELKRLWFYRKPACAEKAWGQWFEQAQQSGIAALQKFAQRLQGYWHGIVARCRHPLNTSVVEGINNTIKVIKRRAYGYRDEQYFFLKIRAAFPGIPR
>NZ_CP008711.1|WP_041283566.1|3310749_3312213_+|IS1182-like-element-ISBma2-family-transposase
MLKTPMPTQHELEMVTLEELVPKDHLLRQIDAAVDFEFIRAKVAHLYCADNGRPALDPVVMFKLLFIGYLFGVRSERQLMREVQVNVAYRWFARFRLTDKVPDASTFSQNRRRRFTDTTVYQEIFDEIVRQAIKRGLVDGRVLYTDSTHLKANANKGKFDVVKLEQTPAAYTEALNAAVDADRAAHGRKPLDRDDDEPPSSKDTKLSRTDPDSGYMVRDDKPKGFFYLDHRTVDAKHAIITDTHVTPASVHDSQPYLDRLDRQRERFEFKVEAVGLDAGYFTPAVCQGLEERGIAGVMDYRTPNHKPGMFYKRQFKYDAYRNEYVCPQGQALPYSTTNRLGYREYKSNAQICGRCPVRSQCTNSAIAVKVVTRHVWERAKERVDARRLTEWGQRIYARRKQTVERSFADAKQLHGHRYARMRGLRKVAEQCLLAAAAQNIKKIAMLLARKRKKGPAGPDWRFVRMLLRLVSGLRCSFDYPLAANPQS
>NZ_CP008711.1|WP_004198297.1|3308282_3310166_+|gamma-glutamyltransferase
MTDRIRPRPFRSRAGAIAAAFFAVTAAGCANAPGPGAQNAAAPASAASTPPAAPGAEAPAAPAELSSWVDKPGWTAQRDMIAAAHPLAAQAGQAMLKAGGTAVDAAIAAQMVLMLVEPQASGIGGGAFLLHENGKTIEAYDGRETAPAAATDRLFLDANGKPLPRAALGARTVGAPGALRMLELAHRAHGKLPWRRLFQPAIRLAEQGFPLGPRLAAALANEPSLARDPAARAYFYDRNGAPKPAGTTLKNPQLAATLRLVAAHGANAFYTGAIARDIVATVRQAPNPGVLSMQDLAQYRAKTREPLCADYRKWTVCGMPPPSAGGLVVAQILGLLEAQPDWRQIGAQKPVRNAVGVEPTPFAAHLFSEAGRLAYADRAQYVADPDFVAPPGGSWKRLVERRYVAERARLIGDASAGEASAGSPSGLPPATAADRGAEPPSGSQITVVDRYGNAVSMASTLDERFGSRLMVRGFLLNSQLLDFSPASAEHGKPVANRVQPGKRARSTLAPELVFEKGSSRLMMALGSAGGASTANDVAKTLVGMIDWGMTMQQAIALPNFGSRNGPTELEQGRVSDALAGALKARGHDVRVVELGSSLQGIQRINVEEQSVWFGGSDPRRDGIVAGD
>NZ_CP008711.1|WP_004553812.1|3307097_3307499_-|hypothetical-protein
MQEPPDEQSRRAAPAAEVGPVPASPTAARGRALVRAYGFALAAILVIALFPVLSVAAAGIVADAAGCELNEAAAHPCLIGGVDFGEMLYAMGVLGWLMLGSLPVGGVLLMGWAIALLVHLRQWRAMRRAGARR
>NZ_CP008711.1|WP_004195339.1|3321696_3323463_-|PTS-transporter-subunit-EIIC
MDGNPFLKIQSLGRALMLPIAVLPVAGILLRLGQQDVLNIKMIADAGGAIFENLPLLFAIGVAVGFAKDNNGVAALAGAIGYLIEVAIMKDIDPKLNMGVLSGIIAGVVAGLLYNRYKDIKLPDYLAFFGGKRFVPIITGLACVVLGIVFGYVWQPVQHAIDAVGQWLLTAGAIGTFVYGFLNRLLLVTGLHHIINSLVWFVFGTFTPAGGAAVTGDLHRFFAGDPSAGGFMAGFFPIMMFGLPAACLAMFHEAPKARRAIVGGLLFSMALTSFLTGVTEPIEFSFMFLAPVLYVIHAVLTGLSLAICQLLGVKLGFTFSAGAIDYVLNYGLSTKGWIAIPLGLAYGLAYYGLFRFFIRKFNMATPGREPAGADAQAQSFASGGFVAPTAGASVPRAQRYIAALGGAANLSVVDACTTRLRLSVVDPEKVSEADLRTIGARGVLKRGGSSVQVIIGPEADLIADEIRATLGSGAAAPAAAAAAAPAAAATATAAGAQSGPLDPEPTRWLAVFGGATNVASLDAVAATRLRVVVRDPSAVDRQRLATLDVAWVASDTFHIVCGQSAPRYAQQLAARLPSSDGGTAAQPA
>NZ_CP008711.1|WP_024900792.1|3323575_3326170_-|phosphoenolpyruvate--protein-phosphotransferase
MKQQASHDQIVLVAPLTGPVVPLADVPDPVFSGGMFGDGIGIDPLEGRLLAPCAGVVSHVARTGHAVTIAADGGAEILLHIGIDTVELNGLGFTAKIAEGARVAAGDLLIEFDQDAIARAAHSLVSVIAIANSDAFEVVERAGAGVVKAGETPLLALRARGADASADASASASAGAAADASCAQPAAEARKSITLTQPGGLHARPAARAREAARGLDAHVDVHFEGRKAALQSVVGLLGLGAGEHATIELVATGRDAAKALERVAHELLREAHGEAEEKPARIVSPAPAAAGIARAPLEPNTLAGVCAAPGIAVGTLVRWDDAQIVPPELASGTPAAESLLLDRALAEVDAQLETTVREASRRGAIGEAGIFAVHRVLLEDPALVDAARDLISLGKSAGYAWRETIRAQTAVLADVDDTLLAERAADLRDIDKRVLRALGYASASARELPAEAVLAAEEFTPSDLASLDRERVAALVMARGGATSHAAIIARQLGIPALVAVGDALYAIAQRTQVVVDASAGRLEYAPSALDVERARHERQRLAGVREANRRMSGEAALTRDGHRIEVAANIATLDDARVALDNGADAVGLLRTELMFIHRQAAPTASEHQQSYQSIVDALQGRTAIIRTLDVGADKEVDYLTLPPEPNPALGLRGIRLAQVRPDLLDDQLRGLLAVKPYGSVRILLPMVTDVGELVRIRKRIDDFARAMGRAQAVEVGVMIEVPSAALLADQLAQHADFLSIGTNDLTQYTLAMDRCQADLAAQADGLHPAVLRLVDATVRGAEKHGKWVGVCGALGGDPVAVPVLVGLGVTELSVDPVSVPGIKAQVRRLDYQLCRQRAQDLLALESAQAVRAASREIWPAE
>NZ_CP008711.1|WP_004195337.1|3326227_3327235_-|SIS-domain-containing-protein
MLNEARESARVVAAQLADTRRVEALAQHLATHAPQVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLKVRGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLPSPLAHACEHPLPLLAGPELSVAATKSYIAMLSIAAQLVAFWQRDAALASALRGLPDALEQAGRLDWSSAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPMELIERDYPLLVFAPPGPEQESLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDPIAAILTFYVMAAGLAPARGRDPDAPRHLHKITETH
>NZ_CP008711.1|WP_004195336.1|3327227_3328331_-|N-acetylglucosamine-6-phosphate-deacetylase
MLTGNILTAEGWIHGTLEFENGRITTLSGDAADPSNNDAPYILPGFIDLHVHGAGGADVMEGGDAIETIARTHARYGTTSLLATTMTAPRDELMRVVAELGDVARTRTPGGSRVLGVHLEGPYINPGKLGAQPDAAVSAALDEVLKYLSIAPIRVVTLAPEIAGHIEIISEMAARGVRVQLGHSLGTYDDAVAALKHGACGFTHLFNAMSPLHHRNPGIVGAALAHAEYAEIIPDLLHVHPGAIRAALRAIPRLYVVTDSTSATGMPDGEYRLGSQRVTKCLGGVRLADGTLAGSTLTMDQALRNLVSLGLPIADVSSRMSRYAADYLGLADRGRIARGAWADLAVFDRELNLTATFVEGESIVEYA
>NZ_CP008711.1|WP_004195335.1|3328429_3329164_-|GntR-family-transcriptional-regulator
MDIGWSTLAPDARSDTPLYLQLARNLAGAIHGGAWRAGEALPSERGLSAAAGVSRITARRALALLVEQGLIRRVRGAGSFITPRVADPLSRLVGFTAKMRQRGFAPDSVWLARSLRAASRDELARFGLSPGATVARLERLRRADGVVMAYERSTLPASCVPEPQVLEGSLYGYLQSRGLDVVRASQRFRAVNASADVAQWLGLAPGAALLVITRIGYGADRRAIEATETYCRDDYYDFVAELKR
>NZ_CP008711.1|WP_004195334.1|3329899_3330823_-|LysR-family-transcriptional-regulator
MIDLRRLRYFIVVAEELHFGKAAQRLHLAQPPLTRHISALEGELGLRLFDRSTRSVKLTAEGELFLPHARDVLDAVHRAEIASQRAALGKEGKVALGYTSSVPLCDAFGTLIRNFARSFPDIELSLVEASSAQQGRSIKEGLLDIGIGWKNSFEDYEGCRVKTIAAEPLVVAVSQERALASEASLAVEQLADETFVLFPPGYGSTLDRKAFDLCATAGFTPRRGPSASQMTTMIALVAAGRGVAIVPEAVSTLRKPGVAYVPLTDESALIELVLMWREAGLSLAARSFVEWHKAHVAQRVDGMVGVG
>NZ_CP008711.1|WP_004200179.1|3331256_3333023_+|AMP-binding-protein
MRDSSPLIERLLAPLAEGRNCRAHGVGTLDESGIERVLSYRQLSEAGLRMSAALNALGARAGDIALVALPATGDYLALLVGCVLSGVVPCTVPPPLKRASGSGPQVLEVACRLYRPRFVFTASAHVAELEAQLRDTGARVIDVGILHAASTGAEPRLALRGAGDTHHIQLTSGSTSHPKAAVISHRNVAANIAGIANACGYSKHAADNTVIWLPLHHDMGLVSLLLHLYYRTSLRLMPSMSFVRNPLGWLRRIAHARSTIAVAPTFALRYCVRRFNAATMDGADFSHLRTFLVGAERVDRATLSDFASTFAPYGLHASALQPCYGMAEATLAVTLHRSFDTPNAPAFTHVIADRIDTATLARHRRAAPAPDGHTGATDTLLAVGAPLDDMAYEIRDAQGRLAAEREAGEIFIRGASVMQGYLPSAGAPAPQPFDAHGWFATGDIGYVSGGQLFILGRKKEIIIIRGTNYFPHEIEETIDSHPAVYKGACIAVGIHDETQGTENLVVLVEAHANHVSRDSRAELQARMQQRLGYCAQRIAFVEPGALPRTTSGKPQRLKARAMFVSGELREIAPPPSRRADADRVAPYP
>NZ_CP008711.1|WP_004195331.1|3333103_3334204_+|hypothetical-protein
MMPDTALPDTPARTFPAAAHADAADLPTLAAQPVRERLAAFGAPPAALDALLRAGATRLLDSDMIIAQPRAHAAARAAERATTPLRYEQSAQTEAVLEQIAHEGLAPHFKPFMRGFSHVMSALFLTPEQDAKVQAYRAAGHHLRFLMSDGGGPALAAWRSTVRVEHGRTRLAIDKVWGIEAHRESIGLVAVRAPGAFMPAAYLVWPEQYRTLERAACGEPFLEGGLQLGNVRGEIETTPEDRLRIGGPNVFNKYLTIVRPYFVRALMAHVGWLAREGRLALSPAHESVRRFVADAARAQSRSCVYGADVVQRVLALKFAANELLGDLVRGGAVRRFDDQRDLLALSKMEGSAYRCYYEIRMRTKRA
>NZ_CP008711.1|WP_004195330.1|3334259_3334508_+|acyl-carrier-protein
MSTPAAETLPLLAREVAKILHVETVETNVGIGELGIDSLNIVELIVFCEQLYGSIDPETLNITQYTTLAQLDAELRAPQTAA
>NZ_CP008711.1|WP_004185211.1|3334540_3335428_+|hypothetical-protein
MIELAPIPEPAATALGAARLQLRALAYRRVAAAAGGVGELLEAAAQLGRLLGREALACAGAAAGHAPIDDYVVCSTILSGLLMDDSPHHAAFVGAIASHGPRAADWLTHGYECASWGYVLRETLGKAMHTGTRRLLLQIVDVDIHRFSYWLSHPQWGASGFGVCTLALDVAPGADWPLHLGAAPPAHALAMLGRGFAAFGRERAGVPVAPPFFKEASRRALLKCLGDAPVHPDGHARFGHAFGSDPWISLLLHRCAPGAPAAARAIVGSLALNGYFAIAEIGYDAAARFRLDDTA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP008711_1	1.3\|3321435\|17\|NZ_CP008711\|CRISPRCasFinder	3321435-3321451	17	NZ_CP008711.1	3321463-3321479	0	1.0

1. spacer 1.3|3321435|17|NZ_CP008711|CRISPRCasFinder matches to position: 3321463-3321479, mismatch: 0, identity: 1.0

ctcgcgtctcgcgtctc	CRISPR spacer
ctcgcgtctcgcgtctc	Protospacer
*****************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP008711_1	1.1\|3321337\|31\|NZ_CP008711\|CRISPRCasFinder	3321337-3321367	31	NZ_CP013578	Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence	29390-29420	8	0.742
NZ_CP008711_1	1.1\|3321337\|31\|NZ_CP008711\|CRISPRCasFinder	3321337-3321367	31	NZ_CP013572	Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence	29390-29420	8	0.742

1. spacer 1.1|3321337|31|NZ_CP008711|CRISPRCasFinder matches to NZ_CP013578 (Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence) position: , mismatch: 8, identity: 0.742

ctgtcgttcgtcgttccgaacactgcgctct	CRISPR spacer
gcatcgttcgtcgttccgaaaactccggcgt	Protospacer
 ..***************** *** ** . *

2. spacer 1.1|3321337|31|NZ_CP008711|CRISPRCasFinder matches to NZ_CP013572 (Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence) position: , mismatch: 8, identity: 0.742

ctgtcgttcgtcgttccgaacactgcgctct	CRISPR spacer
gcatcgttcgtcgttccgaaaactccggcgt	Protospacer
 ..***************** *** ** . *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

184758 : 196324

Leptospira_phage(28.57%)

plate,protease,transposase,terminase,portal

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_144245086.1\|184758_185878_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	6.2e-49	39.0
WP_004202811.1\|186258_187005_+	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_004204996.1\|187225_187846_+	ubiquinol-cytochrome c reductase iron-sulfur subunit	NA	NA	NA	NA
WP_004199894.1\|187846_189229_+	cytochrome bc complex cytochrome b subunit	NA	NA	NA	NA
WP_004199892.1\|189251_190010_+	cytochrome c1	NA	NA	NA	NA
WP_004185176.1\|190102_190714_+	stringent starvation protein A	NA	NA	NA	NA
WP_004199890.1\|190783_191305_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.9e-21	51.0
WP_004199888.1\|191526_192024_+\|terminase	terminase	K4NXI4	Burkholderia_phage	2.6e-55	100.0
WP_004199886.1\|192020_193076_+\|portal	phage portal protein	K4NZV0	Burkholderia_phage	5.7e-206	99.4
WP_004202809.1\|193119_193476_-	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.9e-42	100.0
WP_004199884.1\|193478_193775_-	type II toxin-antitoxin system RelE/ParE family toxin	A4JWV2	Burkholderia_virus	2.8e-49	98.0
WP_144245087.1\|194582_195702_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.4e-48	39.1
WP_004204912.1\|195841_196324_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_2

467749 : 525353

Vibrio_phage(17.65%)

protease,tRNA,transposase,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162473628.1\|467749_469158_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.7e-80	38.7
WP_004190029.1\|469329_470100_-	exodeoxyribonuclease III	R4TWA8	Phaeocystis_globosa_virus	3.4e-30	33.8
WP_024900631.1\|470131_470971_-	polyphosphate kinase	NA	NA	NA	NA
WP_004190092.1\|471097_472570_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_004189326.1\|472572_474063_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_004189769.1\|474175_474475_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_024900632.1\|474840_475884_+	rod shape-determining protein	NA	NA	NA	NA
WP_004189331.1\|476003_477077_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_004523092.1\|477073_477586_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_004189575.1\|477769_480178_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_004189171.1\|480189_481338_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_024900633.1\|481660_482437_-	sel1 repeat family protein	NA	NA	NA	NA
WP_004189570.1\|482433_483219_-	2-dehydro-3-deoxyglucarate aldolase	NA	NA	NA	NA
WP_004189793.1\|483640_484093_-	6-carboxytetrahydropterin synthase QueD	A0A088FAL2	Vibrio_phage	7.6e-14	30.8
WP_004189241.1\|484112_484745_-	7-carboxy-7-deazaguanine synthase	R4TAH8	Halovirus	2.1e-06	30.9
WP_004190026.1\|484838_485573_-	7-cyano-7-deazaguanine synthase QueC	A0A1B0Z0B4	Vibrio_phage	1.6e-50	42.5
WP_004189647.1\|486040_486724_-	response regulator	NA	NA	NA	NA
WP_004189034.1\|486724_489133_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_004188929.1\|489134_489725_-	DUF4390 domain-containing protein	NA	NA	NA	NA
WP_004189046.1\|489721_491131_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_004189409.1\|491508_492366_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_004189288.1\|492475_493111_-	LysE family translocator	NA	NA	NA	NA
WP_004200737.1\|493231_494215_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.3e-07	38.0
WP_004201745.1\|494246_494750_-	peptide deformylase	A0A067XQZ3	Caulobacter_phage	2.7e-12	34.3
WP_004190020.1\|494978_496169_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	2.0e-21	39.2
WP_004190199.1\|496228_496600_+	thioredoxin family protein	NA	NA	NA	NA
WP_004200734.1\|496810_499420_+	DNA topoisomerase III	A0A2P1ELA0	Moumouvirus	7.7e-18	25.7
WP_004189230.1\|499641_500697_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004188904.1\|501146_502163_+	D-2-hydroxyacid dehydrogenase family protein	NA	NA	NA	NA
WP_004189208.1\|502283_503153_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_004200732.1\|503190_503595_-	PaaI family thioesterase	NA	NA	NA	NA
WP_004187628.1\|503985_505206_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	7.8e-239	99.5
WP_144245090.1\|505367_506488_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.2e-47	38.7
WP_004200731.1\|506559_507042_+	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_004188977.1\|507038_507323_+	hypothetical protein	NA	NA	NA	NA
WP_004200730.1\|507395_508487_-\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	2.0e-193	92.3
WP_004200729.1\|508885_509296_+	hypothetical protein	NA	NA	NA	NA
WP_004189258.1\|509432_510308_-	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	9.6e-74	47.3
WP_004190014.1\|510318_511431_-	histone deacetylase	A0A2K9KZC4	Tupanvirus	3.2e-37	30.8
WP_004201742.1\|511459_512554_-	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004189434.1\|512696_513665_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004189874.1\|513767_514337_+	periplasmic heavy metal sensor	NA	NA	NA	NA
WP_004189689.1\|514923_515472_+	hypothetical protein	NA	NA	NA	NA
WP_004189592.1\|515735_517184_+	RNA polymerase sigma factor RpoD/SigA	A0A2I7SAT0	Vibrio_phage	4.9e-30	33.5
WP_004200727.1\|517202_518816_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_004200726.1\|518975_519917_-	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004190110.1\|519913_521008_-	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	3.8e-19	37.4
WP_004197761.1\|521409_521826_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_004197759.1\|522003_522558_-	YaeQ family protein	NA	NA	NA	NA
WP_024900531.1\|522773_523121_-	hypothetical protein	NA	NA	NA	NA
WP_004524603.1\|523606_524167_-	spermidine N1-acetyltransferase	NA	NA	NA	NA
WP_038802950.1\|524232_525353_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_3

924387 : 959131

Streptococcus_phage(27.27%)

holin,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004198632.1\|924387_924741_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_004198631.1\|924758_925589_+	methylenetetrahydrofolate reductase [NAD(P)H]	NA	NA	NA	NA
WP_004198630.1\|925772_927263_-	6-aminohexanoate-cyclic-dimer hydrolase	NA	NA	NA	NA
WP_004198629.1\|927359_928052_-	carboxymethylenebutenolidase	NA	NA	NA	NA
WP_024900621.1\|931169_932303_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004195764.1\|932493_933702_-	MFS transporter	NA	NA	NA	NA
WP_004185224.1\|934014_934695_+	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
WP_004195767.1\|935079_935373_+	H-NS histone family protein	NA	NA	NA	NA
WP_004195769.1\|935612_936803_+	cation transporter	NA	NA	NA	NA
WP_004195771.1\|936981_937440_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_004195773.1\|937530_938187_-	hypothetical protein	A0A2L0UZL4	Agrobacterium_phage	1.1e-32	38.2
WP_004195775.1\|938183_938828_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_004553005.1\|939428_940064_+	septal ring lytic transglycosylase RlpA family protein	F5B3X9	Synechococcus_phage	1.6e-22	63.1
WP_144245094.1\|940192_941655_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	6.8e-80	38.6
WP_004189292.1\|941813_943424_-	multicopper oxidase family protein	NA	NA	NA	NA
WP_004189626.1\|943436_943619_+	hypothetical protein	NA	NA	NA	NA
WP_004189552.1\|943591_944851_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_004189780.1\|945118_945697_+	pseudouridine synthase	NA	NA	NA	NA
WP_144245095.1\|945911_947031_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	5.2e-48	39.1
WP_004191998.1\|949106_950571_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004185841.1\|950731_951310_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.1e-44	44.7
WP_004197496.1\|951506_952889_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	6.1e-30	27.5
WP_004200482.1\|952883_953114_+	hypothetical protein	NA	NA	NA	NA
WP_004555967.1\|953346_954375_+	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_004196455.1\|954355_954562_+	Trm112 family protein	NA	NA	NA	NA
WP_004185994.1\|954735_955527_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_004185840.1\|955735_956398_+	adenylate kinase	NA	NA	NA	NA
WP_144245096.1\|956514_957976_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	5.2e-80	38.6
WP_004196460.1\|958080_958284_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004194131.1\|958816_959131_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6

DBSCAN-SWA_4

1130780 : 1139622

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004189214.1\|1130780_1132181_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.1e-78	38.3
WP_004200795.1\|1132149_1133136_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	8.8e-15	26.5
WP_004190173.1\|1133194_1134187_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_004189725.1\|1134258_1134576_+	competence protein ComE	NA	NA	NA	NA
WP_004532363.1\|1134899_1135802_+	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	1.9e-53	39.9
WP_024900718.1\|1136027_1137335_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004188957.1\|1137513_1138437_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	8.4e-44	36.5
WP_004190087.1\|1138779_1139622_-	alpha/beta hydrolase	A7XCB7	Tanapox_virus	7.2e-18	27.2

DBSCAN-SWA_5

2296104 : 2362425

Leptospira_phage(20.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_144245106.1\|2296104_2297224_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.2e-49	39.9
WP_004192968.1\|2297689_2299030_-	nitrate/sulfonate/bicarbonate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	8.2e-32	37.7
WP_004192556.1\|2299083_2300841_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_004198606.1\|2301337_2301604_+	hypothetical protein	NA	NA	NA	NA
WP_004193003.1\|2301677_2302991_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_024900821.1\|2302974_2303673_-	response regulator	W8CYM9	Bacillus_phage	6.4e-28	36.2
WP_004192043.1\|2303914_2304460_+	periplasmic heavy metal sensor	NA	NA	NA	NA
WP_004198602.1\|2305887_2306664_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004522525.1\|2306874_2307564_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_004193161.1\|2307560_2308274_+	ABC transporter permease	NA	NA	NA	NA
WP_004553879.1\|2308296_2309076_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-26	40.0
WP_004191758.1\|2309970_2311059_+	porin	NA	NA	NA	NA
WP_004193987.1\|2311515_2311854_-	P-II family nitrogen regulator	NA	NA	NA	NA
WP_004198600.1\|2311914_2313615_-	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	5.8e-91	36.8
WP_024900822.1\|2313735_2314914_+	N-acetyltransferase	NA	NA	NA	NA
WP_011807749.1\|2315545_2315935_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004199405.1\|2315913_2316810_+	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	2.1e-07	43.1
WP_004192356.1\|2316868_2317396_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	9.0e-51	53.8
WP_004193515.1\|2317556_2318996_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004192728.1\|2319084_2319843_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004192161.1\|2319881_2321189_+	MFS transporter	NA	NA	NA	NA
WP_004193604.1\|2321369_2322560_-	heme biosynthesis protein HemY	NA	NA	NA	NA
WP_004193146.1\|2322564_2324544_-	fused uroporphyrinogen-III synthase HemD/membrane protein HemX	NA	NA	NA	NA
WP_004193185.1\|2324543_2325533_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_004199404.1\|2325567_2325747_-	hypothetical protein	NA	NA	NA	NA
WP_004191560.1\|2325859_2328844_+	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_041283509.1\|2328990_2330454_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	6.8e-80	38.6
WP_144245107.1\|2330617_2331737_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.8e-48	39.5
WP_004526841.1\|2332754_2333159_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_004197408.1\|2333217_2333622_-	integration host factor subunit alpha	A0A1P8CWT5	Bacillus_phage	2.8e-12	41.1
WP_004193113.1\|2333694_2336127_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_004191909.1\|2336214_2337228_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	7.8e-27	38.8
WP_004192938.1\|2337376_2337736_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_004191477.1\|2337766_2337964_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_071810680.1\|2338156_2338681_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	4.1e-11	28.7
WP_004191232.1\|2338730_2340638_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.7e-123	37.5
WP_004205973.1\|2341096_2343334_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	NA	NA	NA	NA
WP_004197416.1\|2343378_2343732_-	RidA family protein	NA	NA	NA	NA
WP_011832186.1\|2343805_2344942_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_024431237.1\|2345109_2346012_-	hypothetical protein	NA	NA	NA	NA
WP_004192063.1\|2346037_2346943_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004193204.1\|2347130_2347688_+	ester cyclase	NA	NA	NA	NA
WP_004197421.1\|2347702_2348803_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_004548137.1\|2348846_2349569_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004191181.1\|2349972_2350614_-	CoA transferase subunit B	NA	NA	NA	NA
WP_004192091.1\|2350615_2351320_-	CoA transferase subunit A	NA	NA	NA	NA
WP_004191840.1\|2351572_2352118_+	PAS domain-containing protein	NA	NA	NA	NA
WP_004197424.1\|2352687_2354220_+	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_004193006.1\|2355148_2356222_+	hypothetical protein	NA	NA	NA	NA
WP_004191805.1\|2356597_2357029_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_004192152.1\|2357073_2357853_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_004193882.1\|2358033_2359707_+	electron transfer flavoprotein-ubiquinone oxidoreductase	NA	NA	NA	NA
WP_144245108.1\|2360313_2361433_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	6.2e-49	39.1
WP_024900959.1\|2361478_2361892_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	5.8e-29	52.0
WP_004521230.1\|2361891_2362425_-\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

2385968 : 2463501

Klosneuvirus(20.0%)

tRNA,transposase,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191922.1\|2385968_2388836_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.8e-146	39.3
WP_004192544.1\|2388922_2389804_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	1.9e-69	47.9
WP_004526815.1\|2389864_2390482_-	DUF4136 domain-containing protein	NA	NA	NA	NA
WP_004192128.1\|2392975_2394340_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_004193573.1\|2394336_2395041_-	response regulator transcription factor	NA	NA	NA	NA
WP_004192096.1\|2395368_2395755_-	hypothetical protein	NA	NA	NA	NA
WP_004193727.1\|2396030_2396261_-	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_004192573.1\|2396425_2397463_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_004193713.1\|2397475_2398495_-	inositol 2-dehydrogenase	NA	NA	NA	NA
WP_004191536.1\|2398487_2399369_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_004192875.1\|2399613_2400663_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004192697.1\|2400763_2401909_+	ABC transporter permease	NA	NA	NA	NA
WP_024900516.1\|2401921_2402722_+	sugar ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-13	28.4
WP_004191266.1\|2402735_2404736_+	5-dehydro-2-deoxygluconokinase	NA	NA	NA	NA
WP_004196072.1\|2404746_2406732_+	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing)	NA	NA	NA	NA
WP_004192432.1\|2406728_2407649_+	myo-inosose-2 dehydratase	NA	NA	NA	NA
WP_004196071.1\|2407648_2408452_+	5-deoxy-glucuronate isomerase	NA	NA	NA	NA
WP_004193939.1\|2408568_2409273_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_051517624.1\|2409269_2411555_-	branched-chain amino acid ABC transporter ATP-binding protein/permease	A0A2R8FFL6	Cedratvirus	2.4e-07	26.2
WP_004191272.1\|2411547_2412483_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004193685.1\|2412487_2412937_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_004196068.1\|2412837_2413182_-	hypothetical protein	NA	NA	NA	NA
WP_024900518.1\|2413178_2414327_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_004193399.1\|2414542_2414878_+	YbjQ family protein	NA	NA	NA	NA
WP_004193543.1\|2414977_2415529_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_004196065.1\|2415820_2416498_+	hypothetical protein	NA	NA	NA	NA
WP_144245109.1\|2419203_2420324_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_011807697.1\|2420354_2421071_-	YbfB/YjiJ family MFS transporter	NA	NA	NA	NA
WP_004192193.1\|2421217_2422183_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_024900630.1\|2422703_2425328_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	5.5e-80	39.2
WP_004204969.1\|2426004_2427225_+	CoA transferase	NA	NA	NA	NA
WP_004534928.1\|2427548_2427758_-	hypothetical protein	NA	NA	NA	NA
WP_004193654.1\|2428037_2429747_+\|tRNA	glutamine--tRNA ligase/YqeY domain fusion protein	A0A222YZ70	Escherichia_phage	8.8e-188	57.5
WP_004192426.1\|2430078_2430561_-	NUDIX hydrolase	A0A2I6PFL2	Proteus_phage	3.7e-19	41.3
WP_004193860.1\|2430579_2430966_-	hypothetical protein	NA	NA	NA	NA
WP_004196725.1\|2433267_2433447_+	hypothetical protein	NA	NA	NA	NA
WP_004192265.1\|2433443_2434304_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_004191662.1\|2434347_2435763_-	cytochrome-c peroxidase	NA	NA	NA	NA
WP_004193177.1\|2435996_2437580_+	acid phosphatase	NA	NA	NA	NA
WP_024900629.1\|2437777_2438971_+	trans-2-enoyl-CoA reductase family protein	NA	NA	NA	NA
WP_024900628.1\|2439589_2440777_+	HlyD family secretion protein	NA	NA	NA	NA
WP_004192651.1\|2440949_2442569_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004192810.1\|2444558_2445191_-	response regulator transcription factor	NA	NA	NA	NA
WP_004552891.1\|2445191_2447273_-	response regulator	A0A1V0SGR3	Hokovirus	1.7e-12	26.8
WP_004196717.1\|2447683_2448649_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_024900626.1\|2448664_2451076_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_004526784.1\|2451120_2451960_-	molecular chaperone	NA	NA	NA	NA
WP_004526783.1\|2451977_2452502_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004191870.1\|2452578_2453139_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_024900625.1\|2453191_2453737_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004542449.1\|2453723_2453909_-	hypothetical protein	NA	NA	NA	NA
WP_004531175.1\|2453994_2454216_-	hypothetical protein	NA	NA	NA	NA
WP_004196705.1\|2454553_2455447_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004538381.1\|2455863_2457150_+	MFS transporter	NA	NA	NA	NA
WP_004192394.1\|2457194_2458187_+	amidohydrolase family protein	NA	NA	NA	NA
WP_004193855.1\|2458654_2458936_+	H-NS histone family protein	NA	NA	NA	NA
WP_004191144.1\|2459188_2459458_-	hypothetical protein	NA	NA	NA	NA
WP_024900624.1\|2460352_2461666_-	divalent metal cation transporter	NA	NA	NA	NA
WP_144245078.1\|2462380_2463501_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_7

3002675 : 3011912

unidentified_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024900817.1\|3002675_3004223_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2
WP_004194373.1\|3004259_3004787_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004194274.1\|3004783_3005467_+	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.6e-05	26.0
WP_004194137.1\|3005531_3006347_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004194350.1\|3006522_3008529_-	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	9.7e-53	35.0
WP_004194374.1\|3008562_3009693_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	2.9e-22	27.6
WP_004194034.1\|3009959_3011912_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP008710

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP008710_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008710_1

1513712-1513857

Orphan

Consensus_repeat	Method
GCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCGAAG	PILER-CR
CGGAATGCCCGATCATCGGGATGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP008710_1

>merge|NZ_CP008710|1|1513712-1513857|PILER-CR,CRISPRCasFinder
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAATGCCCGATCATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCG

>NZ_CP008710|1|1|1513712-1513857|PILER-CR
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAA	TGCCCGAT
CATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAAT	ACCCGATCA
TCGGGATGCTCGATCGCCG

>NZ_CP008710|1|1|1513762-1513847|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGC	CTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGC
CGGAATACCCGATCATCGGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008710.1\|WP_004196918.1\|1523191_1523413_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008710.1\|WP_004529492.1\|1515928_1517770_+\|ribonucleotide-reductase-like-protein	unknown	unknown	gnl\|CDD\|180772
NZ_CP008710.1\|WP_024900580.1\|1505005_1506121_-\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|378454
NZ_CP008710.1\|WP_024900579.1\|1508026_1509916_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NZ_CP008710.1\|WP_004187710.1\|1517844_1519647_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl\|CDD\|225098
NZ_CP008710.1\|WP_004188244.1\|1525873_1527004_-\|porin	unknown	unknown	gnl\|CDD\|238208
NZ_CP008710.1\|WP_004188282.1\|1500696_1501740_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP008710.1\|WP_004187305.1\|1520169_1521201_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236122
NZ_CP008710.1\|WP_004187216.1\|1510226_1512500_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NZ_CP008710.1\|WP_011204701.1\|1525033_1525468_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NZ_CP008710.1\|WP_004187469.1\|1512632_1513028_-\|conjugal-transfer-protein-TraR	unknown	unknown	gnl\|CDD\|224648
NZ_CP008710.1\|WP_004188034.1\|1514414_1515680_+\|polyhydroxyalkanoate-depolymerase	unknown	unknown	gnl\|CDD\|130908
NZ_CP008710.1\|WP_004205322.1\|1506418_1507354_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NZ_CP008710.1\|WP_004200699.1\|1501745_1502978_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	unknown	unknown	gnl\|CDD\|223997
NZ_CP008710.1\|WP_004200705.1\|1524312_1524966_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NZ_CP008710.1\|WP_011807545.1\|1503656_1504259_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008710.1\|WP_004187792.1\|1521197_1523030_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223732
NZ_CP008710.1\|WP_004196898.1\|1504230_1504671_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NZ_CP008710.1\|WP_004187137.1\|1523409_1523859_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341411
NZ_CP008710.1\|WP_004188488.1\|1507769_1507967_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP008710.1\|WP_004187792.1\|1521197_1523030_+\|STAS-domain-containing-protein	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	2.60835e-107
NZ_CP008710.1\|WP_004529492.1\|1515928_1517770_+\|ribonucleotide-reductase-like-protein	gnl\|CDD\|180772	PRK06948, PRK06948, ribonucleotide reductase-like protein; Provisional.	0
NZ_CP008710.1\|WP_024900580.1\|1505005_1506121_-\|SRPBCC-family-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.01885e-11
NZ_CP008710.1\|WP_024900579.1\|1508026_1509916_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	1.25986e-32
NZ_CP008710.1\|WP_004188282.1\|1500696_1501740_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NZ_CP008710.1\|WP_004187305.1\|1520169_1521201_+\|hypothetical-protein	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	5.74738e-30
NZ_CP008710.1\|WP_004187710.1\|1517844_1519647_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl\|CDD\|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	9.00049e-75
NZ_CP008710.1\|WP_004187216.1\|1510226_1512500_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	7.15563e-57
NZ_CP008710.1\|WP_004188034.1\|1514414_1515680_+\|polyhydroxyalkanoate-depolymerase	gnl\|CDD\|130908	TIGR01849, unnamed_protein_product, polyhydroxyalkanoate depolymerase, intracellular. This model represents an intracellular depolymerase for polyhydroxyalkanoate (PHA), a carbon and energy storing polyester that accumulates in granules in many bacterial species when carbon sources are abundant but other nutrients are limiting. This family is named for PHAs generally, rather than polyhydroxybutyrate (PHB) specificially as in Ralstonia eutropha H16, to avoid overcalling chemical specificity in other species. Note that this family lacks the classic GXSXG lipase motif and instead shows weak similarity to some [Fatty acid and phospholipid metabolism, Degradation].	1.36366e-112
NZ_CP008710.1\|WP_004205322.1\|1506418_1507354_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.67997e-62
NZ_CP008710.1\|WP_004200699.1\|1501745_1502978_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	8.93075e-143
NZ_CP008710.1\|WP_004200705.1\|1524312_1524966_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	6.31252e-20
NZ_CP008710.1\|WP_004188244.1\|1525873_1527004_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	2.53339e-55
NZ_CP008710.1\|WP_004187469.1\|1512632_1513028_-\|conjugal-transfer-protein-TraR	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.7869e-14
NZ_CP008710.1\|WP_004196898.1\|1504230_1504671_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	3.1145e-25
NZ_CP008710.1\|WP_004187137.1\|1523409_1523859_-\|CBS-domain-containing-protein	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.39507e-50
NZ_CP008710.1\|WP_011204701.1\|1525033_1525468_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	2.04683e-32

>NZ_CP008710.1|WP_004187469.1|1512632_1513028_-|conjugal-transfer-protein-TraR
MAAFDEHQLQVLGALLRACRQALQADVRAGERQRADEPYANLAGPAPDEGDEANADLFVDVDHALLGMKLAELRDVDAALQRIARRDYGCCADCGQPIAYERLLARPTALRCAPCQRAHERRFATQPRPSL
>NZ_CP008710.1|WP_004187216.1|1510226_1512500_-|FAD-dependent-oxidoreductase
MREFDYLLVGGGIASVTAARTLRGEDASASIAILCGEPVLPYQRPPLSQEWLMGAVQPASITLHDAAFYAAQRIDIALGVRAEQLDRAKRIVRTSSGATFRYGKLLIATGASAKAPALPGFGLDGVHVLHTFAQAQALKDAAAHARRATVLGGGFLGVEIAATLQALGLQVTLVERAPGVMPSLRAPALGGHFEALCRARGIDVLTRCEVRRVLGAQCVEAVETSDGGTRPCDLFVAAVGVTPNCGWLDGSGLALGDGVEVDAFLQTADPDVFAAGDVAHFDDPIFGVRRRIEHWDNAVRQGRIAARNMLGHRLPYRDVSIFYGSVFGLSYNLLGYPVGATETIERGAFDEASYMQLYLADDVLRAAFTIDRPAVEIAALNDAIRLHVNVAAHKMKLSDPNYPLDKLPVQTILILQGGGALGAFECGAVKALEQHGVRPDVISAVSIGAFNGAIVASHPKGATKALEAFWRELSIALPLPYESQWREAWLSSYVLSFGVPNFLKPQWSQLGFDADRLRAKWTSFFDATAIEQLIARYVDFDSLGMSPTRLLIGAVDVETGEPRIFDSYVDRLSPAHVLASGSLPPGMPWTVVDGRPYWDGGVVSNSPLDLVIARCGQIGGRVFIVDLFSGSKALPTNLVEVMLRREEIAYMDRVRNDLRFEEYASDFRDLVDGILAHVDAPSANEIRQQPLYIRLMGNRAAIDIARITLNREGRLSFIEDYDFSSDAIAQLQQQGYDAALVALANGRSRRRRGRRRA
>NZ_CP008710.1|WP_024900579.1|1508026_1509916_+|GMC-family-oxidoreductase
MLGATRSTLWGSRERPRIAAARAPGAAAIRMREEARECAGPRGAGRAPHRATAAGGKTGRRTVRAPSRARAGSNNQKVNRMKQQSYDYDYVVVGSGFGGSVSALRLSEKGYRVLVIEQGRRWTPENLPESTWNLSRWQWRPALGLHGFFSMRFFRHVVVLHGNAVGGGSITYANTLLVPPDKVWREGTWAGLEDWERVMPAHYATAKRMLGVVTNRRMDAADFRLKDMAKLIGVEKSFYPTEVGVFFGDDADAPGTRYADPYFGGAGPERTSCIGCGGCMVGCRHGAKNTLDRNYLYLAERLGAQVREQTKVVDVRPLDARADGAAGYAVEAVSLAAGARGAKSRLTCRGVVFAASSLGTQDLLMRLKEKGSLPRLSDALGKRVRTNAESLIGVRFPKSRVDLSKGVAIGSGIYIDEHTHIEATRYPSGSDTMGLLTTVLTRGAPGGLRVLVWLGALAKLVLTRPLSAWRMIDPRGFARETMIFLCMQTLEGHLTMRLKRRWFWPFSKQLATSGAKIPAYIPAANDFAQKAARALGGVPMTSLTEILLNVPMTAHCMGGAAMARDGVCDGRSRVFGYRNMYVCDGSVLGANLGVNPSLTITALAEHAMSHVPAAREQRWDSTAETPVAA
>NZ_CP008710.1|WP_004188488.1|1507769_1507967_+|hypothetical-protein
MAQTPIGAAGAISPSTARSIFLEIGLALAGRPIQVRRNRAPFTHGTPRRRPARGPTARTASPAPV
>NZ_CP008710.1|WP_004205322.1|1506418_1507354_+|LysR-family-transcriptional-regulator
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
>NZ_CP008710.1|WP_024900580.1|1505005_1506121_-|SRPBCC-family-protein
MTQDVTVFRARYRASVHPRYNAWLHGGFVLAYGCAAIAFFLKDVARVSAVQWASVPAAFLLFNWLEFTVHRHVGHVKRRFGAMFYRRHTGDHYSFFANEQIAYREARDWRVILFPAWLIVVFSLGLFALHAVLGRFDANVAGLFASTMLGGYLLYECVHACEHLPDAHPLAKWPWIRQMRVLHRVHHRDALMRSCNFDVIWPLMDWLHGTLRWSEAPGADMSTRMRHEIDIACAGADVLAYASDASRWPEWHPSSLRVDGPAGSLAAGSRFDEDVRAAGRVDRLHWDVVRNEPGVMWQARAANTAGSLRILLTYECSGGPRGARFVRTLHYHSPNPLLRLANALVMRGRVERESAYSLTLLKRRLEAARDA
>NZ_CP008710.1|WP_004196898.1|1504230_1504671_+|SRPBCC-family-protein
MKQQRIEIAEEFDAPVHQVFRFFSEHENLKSIFSPAKIRRISDGEPARNGVGSAREMRVPGAPPFVETVTAYQENELIEYRITRGSPLRDHLGVMRFVPIDERRTYFHYVITFEGKVPFVAPVVRHVLEGSIRRGLGKVATRRLWG
>NZ_CP008710.1|WP_011807545.1|1503656_1504259_+|hypothetical-protein
MNSILAPDNAPPASATRTSPLMSVLARAVVTAPLPGSGRAAEASTRVSTMRAQSASAIRIRSCRRSRSSRHGLPESPACRRKSPARPRSRRAPRPLADHTRMRFSPPRLGVRTARPPPAGRSKPARGASAIRLRVQRRSSRLTMTLINVIVIARAPQTAIVTHRGIGPRAIGRLTARRRAARPSTLETRPSYETATHRNR
>NZ_CP008710.1|WP_004200699.1|1501745_1502978_-|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha
MSQYGPLRLHVPEPTGRPGCKTDFSYLRLSPAGKVRKPPIDVAPADTSDLAYGLVRVLDEHGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHTLALERGDMCFPTYRQQGILMVREYPLVDMMCQLMSNERDPLKGRQLPVMYSTRDAGFFSISGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVVNNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPTLIEWVTYRAGPHSTSDDPTKYRPGDDWTNFPLGDPLERLKRHMIGIGVWSEQDHEDTKAALEAEVLAAQKEAERYGMLADEHVPNVASIFEDVYKEMPAHLRRQRQQLGV
>NZ_CP008710.1|WP_004188282.1|1500696_1501740_-|alpha-ketoacid-dehydrogenase-subunit-beta
MTTASKEGPAASPMTMIQALRSAMDVMLERDGNVVVFGQDVGYFGGVFRCTEGLQNKYGKSRVFDAPINEGGIVGAAVGMGAYGLRPVCEIQFADYFYPASDQIVSEAARLRYRSAAEFIAPLTIRMPCGGGIYGGQTHSQSPEAMFTQVCGLRTVMPSNPYDAKGLLISAIENDDPVIFLEPKRLYNGPFDGHHERPVTPWSKHPASLVPDGYYTVPLDSAAIVRAGGDVTVLTYGTTVHVSLAAAEETGIDAEVIDLRSLWPLDLDTIVESVRRTGRCVVVHEATRTCGFGAELIALVQEHCFHWLEAPVERVTGWDTPYPHAQEWAYFPGPNRVGDALRRAMEN
>NZ_CP008710.1|WP_004188034.1|1514414_1515680_+|polyhydroxyalkanoate-depolymerase
MLYAWLEAQREFFRACQPWAGAAQRAGAGARPAGWPTWGPMARAADAVPAPPPFAIASIEIDGAAVPVDECVVDDTPFCALRKFSRRLRGDAAARPAVFLCTPLAGHHAVMLRETVETILATRDVYVTDWRNARDVPPEAGAFGLDDYVCTLERFVAGAAGDGLHMMAVCQATVPALAAVALLAARDVHVTSVALLGGPVDTRSHPTLIDRFALEHDLDWFRRTAIDIVPPPYAGAGRRVYPGFIQHAAIIVAHPQRRASLESRYWTAWMTGDFAAAARCLREMNEYGAVLDMTERYFLDTIRVIFHERLLAQGRWSIGRRLVAPRRLTRTALCTIEGGRDDIAGAGQTHAAHALCDAVPDAVRERITEPDCDHYDLFLGPRWRRTIHPALDAFWTRAEAARAAAGEPRPTAERAERRIAH
>NZ_CP008710.1|WP_004529492.1|1515928_1517770_+|ribonucleotide-reductase-like-protein
MRTINKRTRTIAHADSFVRMIGDMDDQPICDAVFADRYALPGEHSRAQACARVARALALAEPMATRSGAARRFYRNLLNGAFGAGRIMARAGAAPDQTMASCFVHPIRAPAALTRFHPNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALPGADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGRERIDATSPCGAQPLPPYGSAMLGAIDLSRFVRNPFGAGGEPRFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYIASDLRHHAYAASAELAAERGAYPLCDRHAHLDALRAGPPLPHAVCHAIERDGLRHSHLTSFAPVIGVSLAFGDHCSPGIEPARAWIEHRPVRAGAAGAPGMRAENHAHRLFRSLRGERAALPDYFATDADVAPGERLAMRVALQPYVDAGIDNTLTLANHYSLEEVNALLFAAWRAKLKSVAIRRADLARDAQPSDDDGV
>NZ_CP008710.1|WP_004187710.1|1517844_1519647_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MTTGAVAARRLPRRGTARGRRAPSRAFTIHGGDEMRRSRPPKPAKPAAVRRRPHGAARAHAIRGNGPQRRAVRERAARRLSRDIDAALRRASTYPHPAGPIVRIETHLSVVYLVGRFAYKRLKPFDFGFANFTELAARRRACEAELALNRPLAAPIYLAAGPLVRRARGLRLFGAGAAVDHVVRMRRFDERMLFSRLLARGALDAADIDAAATRLAAYHLHAPRDIPRRAYGSARELRRQLDDMLAPLERALGAALPASLRAWCVRRCDELAAHLDARRADGYVRACHGDLHLNNVVKRGRDALMFDCIDFDDALRWIDVINDLSFLLMDLHAHDRAALAHRLLNRWLDETGDFAGLAALPLYVAYRALVRALVATMRAGGDAAARAARIERARRYVDVAAHAARARRPCLLLCHGYSGSGKSVASRALADVSGAIRLSSDSERKRARPFAAVDARPLPASAYTPQQIDAQYERLRALARDVLRAGYTALVDATFLSHARRARFFALARELGVPVYVLDFHASRACLERRVDARAAARDDRSDAGAAVLATQRASADPLDADERARTIGFDTDVPLATLRSAGYWRPVLDAARVDAQATR
>NZ_CP008710.1|WP_004187305.1|1520169_1521201_+|hypothetical-protein
METSPLKTTTPEAIPPFNPSASVEDKLRLAIHYAILAPSSHNTQPWRFMVGDGSVMLCADRLRALSVVDPYDRELLISCGAALLNLRVALSRFGFAYVIDMFPSPSDPDVIALVRLDPHGYHDESLVPLFDAILERVTTRTPYANEAVPCDVQRALVDAGAAEGAEIACVDAPHALDEIAELIADADRLQFADPRFRRELANWVHPRRHDDGMPAFAAGVPALLDFATPVVASAIRTFDLGGGLAAMHHKLVDGSPLIVGISTASDDRDAWVATGQALERVLLVAAAAGLTASYLNQPIEIDALRERLRPLLHVDAHPQLLLRIGRGPVVAHAPRRPLMDVVS
>NZ_CP008710.1|WP_004187792.1|1521197_1523030_+|STAS-domain-containing-protein
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRTYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGASIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQHDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRHPGATLTRGLVAFRWDAPLFHANATIFRDHVRDAIAEAGAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>NZ_CP008710.1|WP_004196918.1|1523191_1523413_-|hypothetical-protein
MTDAVVSSRLAPCCVYIDIQGEGDVDVDAEGNGNGNIDVIDSKRCEPSGVEPVERAVRRPRYRAQSGCLSGIH
>NZ_CP008710.1|WP_004187137.1|1523409_1523859_-|CBS-domain-containing-protein
MNAAEICTREVVACRRTDTVLDAAHLMRDRHVGDLIVVDDAGHAHAPVGMLTDRDIVLSLIAKEVDPAALFVGEIMSAPAAVVHEHDSLWTIAQRMRLTGVRRMPVVNADGALVGMVSVDDLLASVAALFDEIASISRRQIHFEEKARD
>NZ_CP008710.1|WP_004200705.1|1524312_1524966_+|SagB/ThcOx-family-dehydrogenase
MSDPELLTYQPIAVALPGPAEAGAPAVIDLPPPDLGAGLPLMSALSLRASTREFSSAALAPTTLGELLWAADGVNRPTTGGRTAPSAHAFNEIDIYAALPDGVYRYDAALHRLLLKHAVDARNLTGYQDFVGAAPLDLIYVVRMSRLLSMPKPLRETFSAVAAGAIAQNVALYCASTGLGCVVRGWINHRLLAEALSLNEDELPILAQTVGKPAAHP
>NZ_CP008710.1|WP_011204701.1|1525033_1525468_-|Hsp20/alpha-crystallin-family-protein
MSNVTRYDPFSLEPVSDLFRGLFRPLRGIADADDEKLASMKIDVTENDQAYAVKAELPGVDKNDINVQIDGNTVSISAKVERNKELKEGERVIRRERYSGEFARTFSLANELDRDAASAQYQDGVLSLTLPKKASSEKKKLTIG
>NZ_CP008710.1|WP_004188244.1|1525873_1527004_-|porin
MMNAKSIAAAALAVAQAGLAHAQSSVTLYGALDAGVLWQNTSAASFSPTAPNTGAVVRFKDGGVYSSLWGIKGTEDLGGGYRVNFRLQGAFDGGTGKFGLSDAPGAVAAFNQIATLGVSGPFGTFNAGRQIVPMIYAMADTDVRAARFFGSVLTAWLGLNTAAGWPGNSTNAPIGALYDSDALVYQSPAFGGASLALEYAPGGVPGGVQRGARASIVLKYASNALNLAAVYYNGHDTNPAPGASATGLDNNRFVYVGAQYKLKDVAVSASYGNGRNPARGDRVNLDMFAFGLGYRVSPFFRVSSGVYYLKDRNRSANRSTSIVLGADYELSKHTTLYAQGGRVDNRGTMAQMLAYGQPVAPGLATTAAMLGMRHSF

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Crispr_ID: NZ_CP008710_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008710_2

1608523-1608615

Orphan

Consensus_repeat	Method
GCGCGTCGGCGCGCGCGGCGGCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP008710_2

>merge|NZ_CP008710|2|1608523-1608615|CRISPRCasFinder
GCGCGTCGGCGCGCGCGGCGGCGATCAGCCGCTCGCGCTCGGCGGCGGCCTGCGCGAGCGCGTCCTTCAGCGCGTCGTCGCGCGCGGCGGCGA

>NZ_CP008710|2|2|1608523-1608615|CRISPRCasFinder
GCGCGTCGGCGCGCGCGGCGGCGA	TCAGCCGCTCGCGCTCGGCGGCGGCCTGCGCGAGCGCGTCCTTCA
GCGCGTCGTCGCGCGCGGCGGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008710.1\|WP_004187346.1\|1609078_1609780_-\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|237383
NZ_CP008710.1\|WP_004187423.1\|1612586_1612844_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008710.1\|WP_004198322.1\|1603421_1603925_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008710.1\|WP_004188525.1\|1597289_1598414_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223912
NZ_CP008710.1\|WP_024900728.1\|1611010_1612615_-\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|183615
NZ_CP008710.1\|WP_004188594.1\|1614779_1616183_+\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236180
NZ_CP008710.1\|WP_004188221.1\|1610565_1611021_-\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|184057
NZ_CP008710.1\|WP_004201694.1\|1609776_1610085_-\|membrane-protein	unknown	unknown	gnl\|CDD\|274462
NZ_CP008710.1\|WP_004188840.1\|1612975_1614769_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|213656
NZ_CP008710.1\|WP_004187376.1\|1598563_1600399_+\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_CP008710.1\|WP_038802228.1\|1610077_1610569_-\|AtpZ/AtpI-family-protein	unknown	unknown	gnl\|CDD\|378198
NZ_CP008710.1\|WP_144245075.1\|1616879_1618000_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|372671
NZ_CP008710.1\|WP_024900724.1\|1594023_1597287_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP008710.1\|WP_004188303.1\|1605241_1606090_-\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|376304
NZ_CP008710.1\|WP_024900726.1\|1606086_1608087_-\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183987
NZ_CP008710.1\|WP_004187193.1\|1608833_1609082_-\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|184067
NZ_CP008710.1\|WP_004198321.1\|1604001_1605027_-\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|176257
NZ_CP008710.1\|WP_024900725.1\|1602854_1603364_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008710.1\|WP_044302747.1\|1600748_1602353_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|185008
NZ_CP008710.1\|WP_004188537.1\|1591434_1592961_+\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|182103

Protein	Function_ID	Function_description	E-value
NZ_CP008710.1\|WP_004187346.1\|1609078_1609780_-\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|237383	PRK13421, PRK13421, F0F1 ATP synthase subunit A; Provisional.	1.54059e-122
NZ_CP008710.1\|WP_004188525.1\|1597289_1598414_+\|ABC-transporter-permease	gnl\|CDD\|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	6.54035e-26
NZ_CP008710.1\|WP_024900728.1\|1611010_1612615_-\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|183615	PRK12597, PRK12597, F0F1 ATP synthase subunit beta; Provisional.	0
NZ_CP008710.1\|WP_004188594.1\|1614779_1616183_+\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	gnl\|CDD\|236180	PRK08190, PRK08190, bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated.	0
NZ_CP008710.1\|WP_004188221.1\|1610565_1611021_-\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|184057	PRK13447, PRK13447, F0F1 ATP synthase subunit epsilon; Provisional.	4.44077e-63
NZ_CP008710.1\|WP_004201694.1\|1609776_1610085_-\|membrane-protein	gnl\|CDD\|274462	TIGR03165, F1F0_chp_2, F1/F0 ATPase, Methanosarcina type, subunit 2. Members of this protein family are uncharacterized, highly hydrophobic proteins encoded in the middle of apparent F1/F0 ATPase operons. We note, however, that this protein is both broadly and sparsely distributed. It is found in about only about two percent of microbial genomes sequenced, with the first ten examples found coming from the Euryarchaeota, Chlorobia, Betaproteobacteria, Deltaproteobacteria, and Planctomycetes. In most of these species, surrounding operon appears to represent a second F1/F0 ATPase system, and the member proteins belong to subfamilies with the same phylogenetic distribution as the current protein family.	3.23546e-10
NZ_CP008710.1\|WP_004188840.1\|1612975_1614769_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.3979e-179
NZ_CP008710.1\|WP_038802228.1\|1610077_1610569_-\|AtpZ/AtpI-family-protein	gnl\|CDD\|378198	pfam09527, ATPase_gene1, Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter. This model represents a protein found encoded in F1F0-ATPase operons in several genomes, including Methanosarcina barkeri (archaeal) and Chlorobium tepidum (bacterial). It is a small protein (about 100 amino acids) with long hydrophobic stretches and is presumed to be a subunit of the enzyme. It carries two transmembrane helices and is a magnesium or calcium uniporter. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI.	6.06437e-17
NZ_CP008710.1\|WP_144245075.1\|1616879_1618000_+\|IS3-family-transposase	gnl\|CDD\|372671	pfam13683, rve_3, Integrase core domain.	5.08611e-33
NZ_CP008710.1\|WP_024900724.1\|1594023_1597287_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.04651e-92
NZ_CP008710.1\|WP_004188303.1\|1605241_1606090_-\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|376304	pfam00231, ATP-synt, ATP synthase.	1.10329e-32
NZ_CP008710.1\|WP_024900726.1\|1606086_1608087_-\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|183987	PRK13343, PRK13343, F0F1 ATP synthase subunit alpha; Provisional.	0
NZ_CP008710.1\|WP_004187376.1\|1598563_1600399_+\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	2.51413e-132
NZ_CP008710.1\|WP_004198321.1\|1604001_1605027_-\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP008710.1\|WP_004187193.1\|1608833_1609082_-\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|184067	PRK13468, PRK13468, F0F1 ATP synthase subunit C; Provisional.	4.45015e-37
NZ_CP008710.1\|WP_044302747.1\|1600748_1602353_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	2.56608e-79
NZ_CP008710.1\|WP_004188537.1\|1591434_1592961_+\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	7.30998e-99

>NZ_CP008710.1|WP_024900726.1|1606086_1608087_-|F0F1-ATP-synthase-subunit-alpha
MTPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSREVSPEASREVSREVSHEADRDAAADAARVAGRAPGRAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAARTAPSPQGGADANVNADANVDAEAEARHKR
>NZ_CP008710.1|WP_004188303.1|1605241_1606090_-|F0F1-ATP-synthase-subunit-gamma
MSDKLAAIEARTDTARQLQTVIGAMQGVAAARAHEAQQRLPGIRASAATVGAAIGDALSAGARSGETAAGARAAPRARFVVVLCSEQGFVGAYNAQLIEHATRPGPSVSREYMMVGSRGAMLADAGGVPLVWRTPMAARADDVVHLANRITDALYAHLAKRGAQPVSIVHAMPGGAARLEVTERRLLPFDYARFDTAPRAQPPLVHLPPATLLAELAQAYVFVELCEAAMLAFAAENEARTRAMIAARESVERALGDLLQAYRIARQDEITADIVELAASGL
>NZ_CP008710.1|WP_004198321.1|1604001_1605027_-|alcohol-dehydrogenase-AdhP
MAQYMKAAVVHAFGEPLRIEEVPVPTPGAGQILVNVKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGFVAAVGEGVRHVKEGDRVGVPWLYTACGHCEYCQTGWETLCHEQQNTGYSVNGSYAEYVLADPNYVGHLPSNVAFDEIAPILCAGVTVYKGIRVTDTRPGQWIAISGIGGLGHVAVQYAKAMGLHVVAVDVAPQKLELARKLGATFVVDASKDDPAAVIQKEIGGVHGVLVTAVSRGAFAQALGMVRRGGTVSLNGLPPGDFPLPIFSTVLNGITVRGSIVGTRRDLQESLDFAAEGLVRAHIHRDKLEHINGVFSALREGKVDGRIVLTGQ
>NZ_CP008710.1|WP_004198322.1|1603421_1603925_-|hypothetical-protein
MRGAGRASPSRARRYENVSKEPNTHREAGAPVHRYRLQVRNMNGECRTYELRLSSLDDGYTLEIDEWLNFPDTHLGDVTPVHVSRPVQFAVPAHEFYRRRRAFRTELIESVAAALRAGEVVRMRDSPDEYPGGHAGNPWVNWIRADLRANPGGRPPPVGDDMQDLIH
>NZ_CP008710.1|WP_024900725.1|1602854_1603364_+|hypothetical-protein
MRRIYFLLPDADTARAIVDELLLKRIEWRHIHVVANDRVPLENLPEASIAQSSDLLPALARGTAAGGVTGALAGLAAIAFPPAGLTIAGGAVVAFAIAGAGFGAWVSTMIGVSVPNTRLKHFEDAVDNGELLMMIDVHRDRVEEIEALVKQHHPNAHLEGTDPTIPAFP
>NZ_CP008710.1|WP_044302747.1|1600748_1602353_-|methyl-accepting-chemotaxis-protein
MAPFHRRTTRNARTPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPFATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDSVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>NZ_CP008710.1|WP_004187376.1|1598563_1600399_+|response-regulator
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTERVLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQMLSAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHRALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVVDMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR
>NZ_CP008710.1|WP_004188525.1|1597289_1598414_+|ABC-transporter-permease
MRRLAIIYRLGVKELWSLVRDPILLVLIAYTFTASIYSAATARPDTLHMAPIAIIDEDASPLSARIASAFFPPQFALPRMVTLAEADRGMDAGDFTFALDIPPNFQRDVLAGRPAQIQLNVDATRMSQAFTGNGYVQQIVSGEIDDFARRYRANTAPPVDIAMHMRFNPNLDQTWFGSLMEVINNVTLLSMVLTGAALIREREHGTIEHLLVMPVTPGEIMLAKVWSMGLVVACAAAFSLAFVVRGALHVPIEGSVALFVIGMAIHLFATTSMGIFLATLVRSMPQFGMLLVLVLLPLQLLSGSLTPRESMPFAVQNIMLAAPTTHFVEIGQAILYRGAGIETVWRQFLILAVIGTALFLLSLKRFRKTIGQMA
>NZ_CP008710.1|WP_024900724.1|1594023_1597287_+|ATP-binding-cassette-domain-containing-protein
MSAPSVVRFSDVSLRYGKTVALERITLEIPAGLTIGLIGPDGVGKSSLLALAAGARALQTGAVDALGGDMRSRRHRERVCRRIAYMPQGLGKNLYPTLSVEENLQFFARLFGHDADERRRRIDALTRSTGLFAFLSRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLARAQFWDLIARIRSERPAMSVIVATAYMDEAQRFDWLIAMDAGRVLATGAPAELLARTGCDSLEAAFIALLPEDERRGHKPVTLEPLRADAQTGTAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGTAQLFGKTVDPKDINTRRRVGYMSQAFSLYSELTVRQNLVLHARLFGVPAAEIDARVDEMARRFGLADIYDMLPDSLPLGMRQRLSLAVAMVHKPELLILDEPTSGVDPVARDSFWQLMIDLARRDRVTIFISTHFMNEAQRCDRISLMHAGRVLASDAPAALVRARGAATLEEAFIGYLVDASAQEAQEAQGGAGERPGAGERAAGESVAGRGAATDGDADGAHARPAAYANGAAQHRAPDADAAGTDVAAETGARDDARTAHAAGHSAGNDVRATVGSEVGSEVGSDVGSDVGSDVGSEVASEAGLAASAESGSERGVAHGAERAREPAADAGAAIDVEPGASAESATAAVAPARHAESAATSPRAGNAPAGTPFAAAPAEPPHRAFSAQRALSYMWREMLELRRDPVRATLALIGSLVLMCVIGIGISLDVEDLTYAVLDRDQTELSHDYALNLSGSRYFVERPPIADYAALDRRMRDGELSLAIEIPPNFARDVERGAPAQIGMWIDGAMPQRAETIRGYAIGMHTMWLADKARHRLGVTLAPRAEVVTRYRYNPDVKSLPAMIPAVMPLLLLMLPAMLTALAVVRERELGSILNLYVTPVTRTEFLIGKQVPYVVLAMLNFLLMTMLARIAFDVPVKGSFMTLLLAVLIFNVVATGIGLLASTFTRSQVAAIVMTIIGTMIPTVQFAGLLTPLSSLEGTGRLIGLVYPATYMLSISRGVFNKALSLHELYSQFWPLAACVPVILGATILLLKKQER
>NZ_CP008710.1|WP_004188537.1|1591434_1592961_+|efflux-transporter-outer-membrane-subunit
MTMRNDARHDERHQRRRGIARRAARHAAALALCAAVSGCLSLAPDYARKPPPVPAAYPAYPGEPGAGSRTLEQLGWRAYFVDPRLQALIETALANNRDLRIAAQRVEQARAAYGIRRADQYPTIAANAAYLRFREPGGLLLPSPIIGELYSASLSEVQWEIDFWGRVRSLKAAALDTFLASDASRRAVTVSLIGQVADAYLALCAYDERLALTNETIASRRDSLRIFRRRYEEGAISKLDLTQSEILLQQAQTLGSQLQQARDVQQHALDLLVGTNAAARTPASLDDASIAPDLAPGLPSELLANRPDVVAAEYQLRAAHANIGAARAAFFPRIALTSSIGTGSTELHNLFASGTAAWNFIPNLSVPIFDAGRNIGNLKLANARRDEALAQYEKTIQTAFRDVADALAARHWLADQVRIAQETLATQAERARLAKLRYDSGAARFLEVLDAQRDLLNAQQQLVQTRRALLASRVALYAALGGRLDEPARDGAAPRPSPEPSAKQGPLS
>NZ_CP008710.1|WP_004187193.1|1608833_1609082_-|F0F1-ATP-synthase-subunit-C
MNNLIEVVSIAAAALAVSFGAIGPALAEGRAVGAAMDAIARQPDASGTVSRTLFVGLAMIETMAIYCLVVALLLLFANPFVK
>NZ_CP008710.1|WP_004187346.1|1609078_1609780_-|F0F1-ATP-synthase-subunit-A
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>NZ_CP008710.1|WP_004201694.1|1609776_1610085_-|membrane-protein
MIEMWETARASFDGIAAAIGLALGFAAGACHFVSLGWNSRLFVAGRAGVALALQFARVALAVAVLVVLARAGFGMLVAGSAGFFAARAIAVRRAAALTGARR
>NZ_CP008710.1|WP_038802228.1|1610077_1610569_-|AtpZ/AtpI-family-protein
MMKRRPPEVKREARDDAARGDARHAGAGAAPDDPRGAARRDPSPGSRAARGGATHPAARAAEPAAPKPAADRVERAAHTAAARAPRGARDPEPSLGRRLAQIGVLGWTIVAPTLAALALGRWLDRMFATRVFFSAPLLMLGAALGLWLAWRWMKAQQHGDRDD
>NZ_CP008710.1|WP_004188221.1|1610565_1611021_-|F0F1-ATP-synthase-subunit-epsilon
MGAELRVTIATPARVCVDDLPIVSLRAEDASGAFGIRAGHVDFVTLLRASVVRWRTADGATHYAALDGGVLRVTRGARIEIACRDAVLGESLAELEAVVRGVRATQLDEKRRARVDETRLHAQAVRRLLTYLRPEHAKDGVHAPLKPETLE
>NZ_CP008710.1|WP_024900728.1|1611010_1612615_-|F0F1-ATP-synthase-subunit-beta
MADPQATNGTGAVCAERDASDVGDVSDVGDARDEGAGRVVAVRGAVVDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPLLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVLVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSDPASGSAEPQGARHGR
>NZ_CP008710.1|WP_004187423.1|1612586_1612844_+|hypothetical-protein
MPFVACGSATVAPVWLVRRWLHHNGARRPPADLGQETGNRQTKRGIAQSETIDASASGADKVRAASIVDSNQIPQTYAWLQWPCQ
>NZ_CP008710.1|WP_004188840.1|1612975_1614769_+|alpha/beta-fold-hydrolase
MDTRHAPESGAPDAPLPAHPPASYAPESPYRIFDLAKEASVAKLTSGLSPASLQLALADWLIHLAAAPGKRAELATLALRHAALLGQYLLEAATGRTPAAPAQPSPGDRRFRAGAWQLEPYRFWHQSFLLAEQWWRAATRDVPGVSPHHEDVVAFSARQMLDTFAPANYVATNPEIAQRTALTGGANLAQGVWNYLDDVRRLITKQPPAGAEQFELGRNLATTPGRVVFRNHLIELLQYSPTTPDVYAQPVLIVPAWIMKYYILDLSAHNSLIRYLVGEGHTVFCISWRNVDASDRDLSLDDYRKLGVMDALDTIGAIVPGEKIHATGYCLGGTLLSIAAAAMANTGDDRLASITLLAAQTDFAEPGELQLFIDDSEIHFLESMMWERGYLGAHQMAGSFQLLMSNDLIWSRVIHDYLLGERTPMIDLMAWNADSTRMPYRMHSEYLRHLFLDNDLATNRYVIDGQTVSVHNIRAPFFVVGTEHDHIAPWRSVYKIHYLSGSDVTFVLTAGGHNAGIVSEPGHAKRHYRMKMTAAAAPSISPDEWLAGATDFEGSWWPAWHAWLARHSSPQRVAPPPLGKPGAHTLGDAPGTYVFQK
>NZ_CP008710.1|WP_004188594.1|1614779_1616183_+|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase
MDREILQNRPFDSLAIGDSASLVRTASRDDIDLFAAMSGDVNPAHLDAAFAAHDLFGHVVVHGMWTGALVSAVLGTKLPGPGTIYLDQTLEFRHPVAPGDTITATVTVAEKRPEKRIVLLDTRCTNQDGHVVLRGTATVIAPDTPITWERVPGPEVAVRRHDRYETFVRDAREQPPLRTAIVHPCSPDALRAAIDARDANLIEPILIGPQAKIRAIADAAGVDLAGVPIEAVEHSHAAAARAVEMGGAGEVAALMKGSLHTDELLAAVIGPASRLRTERRISHVYAMDVPAYPKPLLITDAAINIAPTLEQKRDICQNAVDLLHVLGVERPRVAVLAAVETVNPKMPSTLDAAALTVMAARGQIAGAIVDGPLAFDNAVSAVAAMSKGIASPVAGDADVLLVPDLEAGNMLAKQLMYFAGADAAGLVLGTRLPIILTSRADSLRVRIASAALAKLVAERTRAGALAS
>NZ_CP008710.1|WP_144245075.1|1616879_1618000_+|IS3-family-transposase
MKKRFTEQQIIGFLKEAEASMPVKELCRKHGFSDASFYTWRAKFGGMEVSEARRLKGLEVENARLKKLLAEAMLDMEALKVVVKGKPLSPQAKREAVLAIREKVNISERRACRLVGLSRSVLHYDAKPDHENEVLAARLVKLAHERRRFGYRRLHALVEREGTHANHKRIYRLYREAGLAVRRRRKRHGVMIEREQLALPDAPNEVWSIDFVMDALSNGRRVKCLTVVDDFTKEAVDIVVDHGISGLYVARALDRAARFRGYPKAVRTVQGPEFTSRALDQWAYANGVTLKLIQAGKPTQNAYIKSFNGKFRDECLNEHWFTTLAHARAVIAAWRQDYNEQRPHSALNYLAPSEFAAKHRATADAPAAFQELV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

188166 : 221408

Leptospira_phage(40.0%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_144245062.1\|188166_189287_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	6.2e-49	39.5
WP_162473618.1\|189317_189518_-	hypothetical protein	NA	NA	NA	NA
WP_004195426.1\|189521_190823_+	cystathionine gamma-synthase family protein	A0A1V0SL56	Klosneuvirus	3.1e-12	23.2
WP_004195424.1\|190990_191215_-	hypothetical protein	NA	NA	NA	NA
WP_004195418.1\|191651_192353_+	hypothetical protein	NA	NA	NA	NA
WP_004195415.1\|192469_193342_+	arylamine N-acetyltransferase	NA	NA	NA	NA
WP_024900547.1\|193637_194195_+	putative glycolipid-binding domain-containing protein	NA	NA	NA	NA
WP_045598292.1\|194314_194728_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_144245063.1\|194790_195911_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.5e-47	38.7
WP_004528803.1\|197131_197764_-	GTP cyclohydrolase I	S4VV34	Pandoravirus	1.1e-21	35.4
WP_004551882.1\|197768_198062_-	hypothetical protein	NA	NA	NA	NA
WP_004201911.1\|198020_198266_+	hypothetical protein	NA	NA	NA	NA
WP_162473488.1\|198225_199449_-	peptidase	NA	NA	NA	NA
WP_024900597.1\|200166_204198_-	type VI secretion system protein ImpL	NA	NA	NA	NA
WP_004184888.1\|204209_204875_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004206515.1\|204871_206269_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004200965.1\|206301_207099_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004200966.1\|207108_207501_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004200968.1\|207529_208291_-	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_024900598.1\|208287_209352_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004206518.1\|209369_212012_-	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_004184913.1\|212037_215061_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_024900599.1\|215087_218171_-	AAA domain-containing protein	A0A223W0B1	Agrobacterium_phage	4.6e-78	29.5
WP_024900600.1\|218157_219180_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004200971.1\|219167_220910_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004184744.1\|220946_221408_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_2

398817 : 455154

Leptospira_phage(28.57%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_144245065.1\|398817_399938_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.1e-48	39.1
WP_004202495.1\|400079_403088_+	sarcosine oxidase subunit alpha family protein	NA	NA	NA	NA
WP_038799547.1\|403077_403713_+	sarcosine oxidase subunit gamma	NA	NA	NA	NA
WP_004188502.1\|403712_404174_+	dihydroneopterin aldolase	NA	NA	NA	NA
WP_009925642.1\|404674_404914_+	hypothetical protein	NA	NA	NA	NA
WP_004202502.1\|404811_405024_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_004198134.1\|405020_405236_-	hypothetical protein	NA	NA	NA	NA
WP_004187926.1\|405676_405880_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	2.7e-19	67.2
WP_004198135.1\|405901_406084_+	hypothetical protein	NA	NA	NA	NA
WP_004188047.1\|406080_406296_+	hypothetical protein	NA	NA	NA	NA
WP_004187451.1\|406247_406544_+	hypothetical protein	NA	NA	NA	NA
WP_004202506.1\|406657_407083_-	DUF3761 domain-containing protein	NA	NA	NA	NA
WP_004188692.1\|407371_407632_+	hypothetical protein	NA	NA	NA	NA
WP_004188126.1\|407848_408781_+	2-hydroxyacid dehydrogenase	M1HUT5	Acanthocystis_turfacea_Chlorella_virus	2.0e-13	24.8
WP_004188566.1\|408819_409305_+	peroxiredoxin	NA	NA	NA	NA
WP_009934486.1\|409892_412064_+	PAS domain S-box protein	A0A1V0SGX0	Hokovirus	4.9e-18	25.2
WP_004188466.1\|412067_412520_+	response regulator	NA	NA	NA	NA
WP_004188253.1\|412516_413995_+	PAS domain-containing protein	NA	NA	NA	NA
WP_004198884.1\|415737_419115_-	hypothetical protein	NA	NA	NA	NA
WP_154218748.1\|419583_419886_+	DNA polymerase III subunit gamma/tau	NA	NA	NA	NA
WP_004188051.1\|420194_421892_-\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	1.2e-48	29.0
WP_004187839.1\|421911_423381_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_004202513.1\|423423_424011_-	transcriptional regulator BetI	NA	NA	NA	NA
WP_038802950.1\|424368_425488_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004186983.1\|425656_426556_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004201077.1\|426597_426888_-	hypothetical protein	NA	NA	NA	NA
WP_004186962.1\|426777_428097_+	glycosyltransferase	NA	NA	NA	NA
WP_162473623.1\|428168_430313_+	DHA2 family efflux MFS transporter permease subunit	A0A219Y950	Aeromonas_phage	5.8e-104	54.9
WP_004186989.1\|430385_431357_+	membrane dipeptidase	NA	NA	NA	NA
WP_004186987.1\|431507_432041_+	4-vinyl reductase	NA	NA	NA	NA
WP_004186960.1\|432101_434165_+	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_024900507.1\|434167_436093_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_004202150.1\|436097_437270_+	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_004186884.1\|437266_438052_+	drug:proton antiporter	NA	NA	NA	NA
WP_011204351.1\|438103_439345_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004186910.1\|439365_440511_+	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004186918.1\|440620_441484_+	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004186811.1\|441664_443320_+	APC family permease	NA	NA	NA	NA
WP_004186920.1\|443406_444282_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_021252052.1\|444425_445298_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004186939.1\|445460_447014_+\|holin	choline-sulfatase	NA	NA	NA	NA
WP_004530058.1\|447010_448048_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004198249.1\|448044_448167_+	hypothetical protein	NA	NA	NA	NA
WP_004200640.1\|448275_449418_+	porin	NA	NA	NA	NA
WP_004200641.1\|449472_450699_-	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_004198575.1\|450816_452520_-	peptidase	NA	NA	NA	NA
WP_004186852.1\|452991_453936_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_011204354.1\|454203_455154_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA

DBSCAN-SWA_3

630334 : 714993

Leptospira_phage(41.67%)

protease,transposase,integrase

attL 695574:695593|attR 720906:720925

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|630334_631454_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_024900511.1\|631657_636469_-	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_004551771.1\|636993_637512_-	hypothetical protein	NA	NA	NA	NA
WP_004184606.1\|637841_638360_-	membrane protein	NA	NA	NA	NA
WP_004184536.1\|639199_640921_+	gamma-glutamyltransferase	NA	NA	NA	NA
WP_004201091.1\|641117_642434_-	TolC family protein	NA	NA	NA	NA
WP_004184640.1\|643246_643432_+	hypothetical protein	NA	NA	NA	NA
WP_004184575.1\|643568_645692_+	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	2.5e-27	24.9
WP_004184588.1\|645688_646711_+	hypothetical protein	NA	NA	NA	NA
WP_004528592.1\|646723_648019_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004202541.1\|648032_649529_+	OmpW family protein	NA	NA	NA	NA
WP_004524222.1\|649917_650844_+	polyphosphate kinase 2	NA	NA	NA	NA
WP_004537006.1\|650930_651188_-	hypothetical protein	NA	NA	NA	NA
WP_080747472.1\|651598_653206_+	threonine ammonia-lyase, biosynthetic	NA	NA	NA	NA
WP_004184552.1\|653184_653901_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_004184355.1\|653979_655278_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_076841794.1\|655453_655897_+	metal transporter	NA	NA	NA	NA
WP_004528582.1\|656000_657071_-	DMT family transporter	NA	NA	NA	NA
WP_004536930.1\|657206_657797_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	5.8e-22	39.4
WP_038730458.1\|657817_658102_-	hypothetical protein	NA	NA	NA	NA
WP_004184538.1\|658159_658474_-	hypothetical protein	NA	NA	NA	NA
WP_004184214.1\|658574_659099_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_004197859.1\|659128_659359_-	hypothetical protein	NA	NA	NA	NA
WP_004197860.1\|659766_661527_+	fatty acyl-AMP ligase	A0A2K9KZV5	Tupanvirus	4.6e-06	21.9
WP_004184602.1\|661523_663284_+	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_004184547.1\|663280_665074_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_004184201.1\|665084_665375_+	acyl carrier protein	NA	NA	NA	NA
WP_024900541.1\|665834_666638_+	2OG-Fe dioxygenase family protein	NA	NA	NA	NA
WP_123809469.1\|678744_679864_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	5.2e-48	39.1
WP_004197866.1\|680253_680526_+	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_004184766.1\|680638_682033_-	heavy metal sensor histidine kinase IrlS	W8CYF6	Bacillus_phage	1.2e-20	28.9
WP_024900560.1\|682730_685964_-	CusA/CzcA family heavy metal efflux RND transporter	S5VTK5	Leptospira_phage	5.2e-72	24.1
WP_004197872.1\|686009_687479_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004197873.1\|687489_688875_-	TolC family protein	NA	NA	NA	NA
WP_004197875.1\|689110_689395_-	hypothetical protein	NA	NA	NA	NA
WP_004524134.1\|689792_689933_-	bacteriophage protein	NA	NA	NA	NA
WP_038709382.1\|690603_691089_-	membrane protein	NA	NA	NA	NA
WP_004197880.1\|691418_691904_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_024900559.1\|692171_693662_+	arginine-ornithine antiporter	NA	NA	NA	NA
WP_004197883.1\|693961_694570_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_004199606.1\|694701_696702_-\|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	1.1e-104	46.2
695574:695593	attL	NA	NA	NA	NA
WP_004537230.1\|696755_697268_-	hypothetical protein	NA	NA	NA	NA
WP_011204480.1\|698082_699849_+	amidohydrolase family protein	NA	NA	NA	NA
WP_004199157.1\|699979_700651_-	transcriptional regulator	NA	NA	NA	NA
WP_004184876.1\|700801_701899_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004199160.1\|701895_704997_+	MMPL family transporter	S5VTK5	Leptospira_phage	3.6e-46	22.0
WP_004266238.1\|705131_706670_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004202576.1\|706684_706981_+	hypothetical protein	NA	NA	NA	NA
WP_004199609.1\|707026_707644_+	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.9e-34	44.6
WP_004197695.1\|707640_709338_+	WD40 repeat domain-containing protein	NA	NA	NA	NA
WP_004197696.1\|709334_710015_+	1,6-didemethyltoxoflavin N1-methyltransferase	NA	NA	NA	NA
WP_024900397.1\|710088_711780_-\|integrase	tyrosine-type recombinase/integrase	A0A2K9VH72	Gordonia_phage	1.5e-06	24.7
WP_004197698.1\|711876_712323_-	hypothetical protein	NA	NA	NA	NA
WP_038796399.1\|712491_712710_-	hypothetical protein	NA	NA	NA	NA
WP_004199610.1\|712693_713851_-	DUF746 domain-containing protein	NA	NA	NA	NA
WP_038802950.1\|713872_714993_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
720906:720925	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1316278 : 1382777

Leptospira_phage(18.18%)

plate,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004203245.1\|1316278_1317091_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_004203246.1\|1317090_1319718_-	membrane protein	NA	NA	NA	NA
WP_004188178.1\|1319853_1320975_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_004525190.1\|1320973_1321135_+	hypothetical protein	NA	NA	NA	NA
WP_004187693.1\|1321316_1322384_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_004187882.1\|1322432_1323083_-	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_004187125.1\|1323160_1323310_-	entericidin A/B family lipoprotein	NA	NA	NA	NA
WP_004187091.1\|1323306_1324716_-	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_004187288.1\|1325107_1326403_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_004187652.1\|1326395_1327343_-	hypothetical protein	NA	NA	NA	NA
WP_004187998.1\|1328062_1328590_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_004187349.1\|1328750_1331474_+	alpha-ketoglutarate dehydrogenase	NA	NA	NA	NA
WP_004188364.1\|1331725_1332970_-	DUF1479 domain-containing protein	NA	NA	NA	NA
WP_144245068.1\|1334181_1335301_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	4.0e-48	39.1
WP_004196172.1\|1335632_1336892_-	ABC transporter permease	Q6GZ02	Mycoplasma_phage	2.1e-05	22.6
WP_004190757.1\|1338113_1339214_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	6.3e-22	51.0
WP_024900854.1\|1339322_1340852_+	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	2.8e-12	25.9
WP_004190433.1\|1340953_1341988_-	lipase secretion chaperone	NA	NA	NA	NA
WP_004553588.1\|1341991_1343086_-	triacylglycerol lipase	NA	NA	NA	NA
WP_004190808.1\|1343409_1345647_-	TonB-dependent copper receptor	NA	NA	NA	NA
WP_004190837.1\|1345734_1346130_-	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_004190603.1\|1346290_1346827_-	cytochrome b	NA	NA	NA	NA
WP_004190805.1\|1347095_1347731_+	hypothetical protein	NA	NA	NA	NA
WP_011204344.1\|1347861_1348626_-	peptidoglycan DD-metalloendopeptidase family protein	I2E8W3	Clostridium_phage	4.7e-08	38.7
WP_004190911.1\|1348904_1349216_-	cupin domain-containing protein	NA	NA	NA	NA
WP_011204342.1\|1349660_1349993_-	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_004190614.1\|1350191_1351607_-	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	2.1e-41	30.2
WP_004190588.1\|1351595_1351739_+	hypothetical protein	NA	NA	NA	NA
WP_004190461.1\|1352053_1352731_-	DUF938 domain-containing protein	NA	NA	NA	NA
WP_004190245.1\|1352693_1353632_-	NAD-dependent protein deacetylase	S5M4R0	Bacillus_phage	1.4e-14	25.3
WP_004190776.1\|1353628_1355053_-	cytosine permease	NA	NA	NA	NA
WP_011204340.1\|1355569_1356550_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_144245069.1\|1357203_1358324_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.8e-48	39.1
WP_162473620.1\|1358354_1359431_-	RHS repeat protein	NA	NA	NA	NA
WP_004196151.1\|1359360_1360014_-	hypothetical protein	NA	NA	NA	NA
WP_004203275.1\|1360088_1362293_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_004203276.1\|1362289_1364944_-	type VI secretion system ATPase TssH	A0A1S6UBG5	Serratia_phage	2.7e-79	30.9
WP_024900789.1\|1364922_1366413_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004190509.1\|1366409_1368281_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004196148.1\|1368285_1368846_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004190698.1\|1368864_1369356_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004190849.1\|1369415_1370924_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004190671.1\|1370916_1371495_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190988.1\|1371557_1372637_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004190797.1\|1372689_1375287_-	protein kinase	A7IVH4	Paramecium_bursaria_Chlorella_virus	1.0e-14	25.1
WP_004190273.1\|1375285_1375513_+	hypothetical protein	NA	NA	NA	NA
WP_004190681.1\|1376409_1380039_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004190689.1\|1380041_1381358_-	DotU family type VI secretion system protein	NA	NA	NA	NA
WP_004190585.1\|1381373_1382777_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_5

1865782 : 1918117

Burkholderia_phage(33.33%)

integrase,transposase,portal

attL 1891539:1891558|attR 1908239:1908258

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190269.1\|1865782_1866787_+\|transposase	transposase	NA	NA	NA	NA
WP_024900472.1\|1866859_1868389_-	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	1.3e-46	27.9
WP_004190833.1\|1868784_1869864_+	putative membrane protein	NA	NA	NA	NA
WP_144245077.1\|1869929_1871049_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004190721.1\|1871077_1871965_-	hypothetical protein	NA	NA	NA	NA
WP_004190171.1\|1872213_1873434_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	1.0e-238	99.3
WP_004533441.1\|1874017_1874872_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004190802.1\|1874967_1875561_+	LysE family translocator	NA	NA	NA	NA
WP_004195676.1\|1875802_1876213_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004190743.1\|1876465_1877704_+	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_024900588.1\|1877768_1878224_-	YbaK/EbsC family protein	NA	NA	NA	NA
WP_004190582.1\|1879508_1881152_+	DUF3459 domain-containing protein	NA	NA	NA	NA
WP_004190469.1\|1881310_1881940_-	thiamine phosphate synthase	NA	NA	NA	NA
WP_004190954.1\|1881936_1883277_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_004190659.1\|1883362_1884142_-	sensor histidine kinase	NA	NA	NA	NA
WP_004190540.1\|1884234_1885155_-	DMT family transporter	NA	NA	NA	NA
WP_004190343.1\|1885221_1886097_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004190990.1\|1886194_1886578_+	tautomerase family protein	NA	NA	NA	NA
WP_004195687.1\|1886775_1888698_+	CHAD domain-containing protein	NA	NA	NA	NA
WP_024900587.1\|1888732_1889581_+	TOBE domain-containing protein	NA	NA	NA	NA
WP_004190506.1\|1890124_1890826_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.9e-20	32.3
WP_004190258.1\|1890827_1891502_-	molybdate ABC transporter permease subunit	NA	NA	NA	NA
WP_004195689.1\|1891514_1892315_-	molybdate ABC transporter substrate-binding protein	NA	NA	NA	NA
1891539:1891558	attL	NA	NA	NA	NA
WP_004204469.1\|1892755_1893454_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_004190691.1\|1893704_1894853_+	PHB depolymerase family esterase	NA	NA	NA	NA
WP_004190391.1\|1894949_1895108_+	DUF3563 domain-containing protein	NA	NA	NA	NA
WP_004190960.1\|1895220_1895640_-	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_004190487.1\|1895777_1896230_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_038730270.1\|1896349_1896601_+	hypothetical protein	NA	NA	NA	NA
WP_004190835.1\|1896732_1897545_-	hypothetical protein	NA	NA	NA	NA
WP_004190439.1\|1897535_1898531_-	homoserine kinase	NA	NA	NA	NA
WP_004190726.1\|1898624_1899023_-	hypothetical protein	NA	NA	NA	NA
WP_004190957.1\|1899178_1900705_+	AMP nucleosidase	NA	NA	NA	NA
WP_004195697.1\|1900788_1901475_-\|integrase	tyrosine-type recombinase/integrase	E5E3N4	Burkholderia_phage	3.3e-93	81.6
WP_009950031.1\|1901471_1901759_-\|portal	phage portal protein	K4NZV0	Burkholderia_phage	6.4e-43	94.4
WP_004203322.1\|1904100_1904364_+	hypothetical protein	NA	NA	NA	NA
WP_004190352.1\|1904799_1905291_-	DUF523 domain-containing protein	NA	NA	NA	NA
WP_004190916.1\|1905950_1906235_-	hypothetical protein	NA	NA	NA	NA
WP_004190924.1\|1906386_1906656_-	hypothetical protein	NA	NA	NA	NA
WP_004530319.1\|1906652_1907402_-	TIGR00730 family Rossman fold protein	A0A1D8KUT5	Synechococcus_phage	5.6e-22	37.8
WP_004190446.1\|1907403_1910184_+	DNA polymerase I	A0A1J0GVZ7	Streptomyces_phage	5.6e-51	31.0
1908239:1908258	attR	NA	NA	NA	NA
WP_004190401.1\|1910502_1911885_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_038763983.1\|1912218_1914012_-	membrane protein	NA	NA	NA	NA
WP_004204467.1\|1914351_1914573_+	hypothetical protein	NA	NA	NA	NA
WP_004190499.1\|1914725_1915601_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_004190656.1\|1915659_1916529_-	sulfurtransferase	NA	NA	NA	NA
WP_038802231.1\|1916653_1918117_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP008711

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP008710

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection