CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP008777	Burkholderia pseudomallei 576 chromosome 1, complete sequence	3 crisprs	cas3,DEDDh,csa3,DinG,WYL	2	2	9	0
NZ_CP008778	Burkholderia pseudomallei 576 chromosome 2, complete sequence	1 crisprs	cas3,csa3,RT,DinG	0	0	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP008777_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008777_1

3626-3853

Orphan

Consensus_repeat	Method
GCGTTTCGCGTCTCGCGTCTCGCGTCTCGCGT	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP008777_1

>merge|NZ_CP008777|1|3626-3853|CRISPRCasFinder
GCGTTCGTCGTCTGTCGTCTGTCGTCTGTCGTCTGTCGTCTGTCGTCTGTCGTCTGTCGTTCGTCGTTCGTCGTTCCGAACACTGCGCTCTGCGTTGTGCGTCGTGCGTCTCGCGCTCTGCGCTCTGCGCTCTGCGTTTTGCGTTTTGCGTTTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGT

>NZ_CP008777|1|1|3626-3853|CRISPRCasFinder
GCGTTCGTCGTCTGTCGTCTGTCGTCTGTCGT	CTGTCGTCTGTCGTCTGTCGTCTGTCGTTCGTCGTTCGTCGTTCCGAACACT
GCGCTCTGCGTTGTGCGTCGTGCGTCTCGCGC	TCTGCGCTCTGCGCTCTGCGTTTT
GCGTTTTGCGTTTCGCGTCTCGCGTCTCGCGT	CTCGCGTCTCGCGTCTCGCGTCTC
GCGTCTCGCGTCTCGCGTCTCGCGTCTCGCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008777.1\|WP_004522878.1\|4098_5859_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|182338
NZ_CP008777.1\|WP_004543759.1\|5971_8593_-\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP008777.1\|WP_004543839.1\|10852_11587_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP008777.1\|WP_004185211.1\|16994_17882_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004526041.1\|13693_15460_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341254
NZ_CP008777.1\|WP_004195337.1\|8650_9658_-\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|225132
NZ_CP008777.1\|WP_004195330.1\|16713_16962_+\|acyl-carrier-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004195336.1\|9650_10754_-\|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl\|CDD\|238434
NZ_CP008777.1\|WP_004543793.1\|15539_16658_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004543930.1\|851_3353_+\|family-20-glycosylhydrolase	unknown	unknown	gnl\|CDD\|119337
NZ_CP008777.1\|WP_004526046.1\|461_641_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004195334.1\|12336_13260_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176106

Protein	Function_ID	Function_description	E-value
NZ_CP008777.1\|WP_004195336.1\|9650_10754_-\|N-acetylglucosamine-6-phosphate-deacetylase	gnl\|CDD\|238434	cd00854, NagA, N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.	1.64789e-149
NZ_CP008777.1\|WP_004522878.1\|4098_5859_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|182338	PRK10255, PRK10255, PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional.	0
NZ_CP008777.1\|WP_004543759.1\|5971_8593_-\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP008777.1\|WP_004543839.1\|10852_11587_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	2.88028e-74
NZ_CP008777.1\|WP_004526041.1\|13693_15460_+\|AMP-binding-protein	gnl\|CDD\|341254	cd05931, FAAL, Fatty acyl-AMP ligase (FAAL). FAAL belongs to the class I adenylate forming enzyme family and is homologous to fatty acyl-coenzyme A (CoA) ligases (FACLs). However, FAALs produce only the acyl adenylate and are unable to perform the thioester-forming reaction, while FACLs perform a two-step catalytic reaction; AMP ligation followed by CoA ligation using ATP and CoA as cofactors. FAALs have insertion motifs between the N-terminal and C-terminal subdomains that distinguish them from the FACLs. This insertion motif precludes the binding of CoA, thus preventing CoA ligation. It has been suggested that the acyl adenylates serve as substrates for multifunctional polyketide synthases to permit synthesis of complex lipids such as phthiocerol dimycocerosate, sulfolipids, mycolic acids, and mycobactin.	3.38698e-143
NZ_CP008777.1\|WP_004195337.1\|8650_9658_-\|SIS-domain-containing-protein	gnl\|CDD\|225132	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane].	3.14814e-93
NZ_CP008777.1\|WP_004543930.1\|851_3353_+\|family-20-glycosylhydrolase	gnl\|CDD\|119337	cd06569, GH20_Sm-chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NZ_CP008777.1\|WP_004195334.1\|12336_13260_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.03531e-56

>NZ_CP008777.1|WP_004543930.1|851_3353_+|family-20-glycosylhydrolase
MNRISHSLCAALLAAATLLPTASRAQLPARPTAGAAAPATAAPVRPASTPAELAARLANGLAVRVAVDNNHAASAGVPCADLGADWASCATGRLILQNRGHSPLTDGGWKLYLHSIRRLLRIDRPGFTLRHLTGDLYELTPQPGTVRLAQGERIELPFVAEYWLRRYSDVIPRPYVVVDGAAPAVLRYDDTDDELRYVETLPADAQNNSPGNAPPAAAQPVANRALPSVKRQRALPGALDLRGVELTLPELPSAQVAALRERAGTLGLDGARVPVWGVVAPRRLPADIAVPGGYRLAIGPRGAFIEGADRAGLYYGVQTLFSLVPAGGATVPAMLIEDAPRFTHRGMHVDLARNFKPAATLRRLIDQMSAYKLNRLHLHLSDDEGWRIEIPGLPELTDVGARRCHDPSETRCLLPQLGSGPDDRSGGGYLTRDDYVALLRYAAERFVEVIPEIDMPAHSRAAVVSMEARYRRLLAAGREREANAYRLLDAQDTSNLLTVQFYDRRSDLNPCMPGALNFASKVIREIASMHADAQAPLRIWHFGGDEAKNILLGAGFQPLDGADPGKGRVDLAAQDKPWARSPACTALLRRGEIKSIDELPTRFAKQVSAIVNANGIGTMAAWQDGIKHASGPQEFSTRHVTVSLWDTIFWGASDSARDLSAKGYRTVLALPDYLYFDFPYTRNPRERGYYWGSQATDEYKVFSLAPENLPQNAEVFGDRDGNPFEVTSAGAAPSIEGIQGQAWGEVMRNGQLLEYMVYPRLLALAERAWHKADWELPYAAGVRYKLGDTHHVDTAALERDWAGFATVLKQRELPKLERAGIGYRKPTFTLTGE
>NZ_CP008777.1|WP_004526046.1|461_641_+|hypothetical-protein
MHADTPAATRAEIPIETPIDMSAGAPADIRFDARRAAAPKASSAITTAVAPATAARRRR
>NZ_CP008777.1|WP_004522878.1|4098_5859_-|PTS-transporter-subunit-EIIC
MDGNPFLKIQSLGRALMLPIAVLPVAGILLRLGQQDVLNIKMIADAGGAIFENLPLLFAIGVAVGFAKDNNGVAALAGAIGYLIEVAIMKDIDPKLNMGVLSGIIAGVVAGLLYNRYKDIKLPDYLAFFGGKRFVPIITGLACVVLGIVFGYVWQPVQHAIDAVGQWLLTAGAIGTFVYGFLNRLLLVTGLHHIINSLVWFVFGTFTPAGGAAVTGDLHRFFAGDPSAGGFMAGFFPIMMFGLPAACLAMFHEAPKARRAIVGGLLFSMALTSFLTGVTEPIEFSFMFLAPVLYVIHAVLTGLSLAICQLLGVKLGFTFSAGAIDYVLNYGLSTKGWIAIPLGLAYGLAYYGLFRFFIRKFNMATPGREPAGADAQAQSFASGGFVAPTAGASVPRAQRYIAALGGAANLSVVDACTTRLRLSVVDPEKVSEADLRTIGARGVLKRGGSSVQVIIGPEADLIADEIRATLGSGAAAPAAAAAAAPAAAATAAGAQSGPLDPEPTRWLAVFGGATNVASLDAVAATRLRVVVRDPSAVDRQRLATLDVAWVASDTFHIVCGQSAPRYAQQLAARLPSSDGGTAAQPA
>NZ_CP008777.1|WP_004543759.1|5971_8593_-|phosphoenolpyruvate--protein-phosphotransferase
MKQQASHDQIVLVAPLTGPVVPLADVPDPVFSGGMFGDGIGIDPLEGRLLAPCAGVVSHVARTGHAVTIAADGGAEILLHIGIDTVELNGLGFTAKIAEGARVAAGDLLIEFDQDAIARAAHSLVSVIAIANSDAFEVVERAGAGVVKAGETPLLALRARGADASADASADASADASASASAGAAADASCAQPAAEARKSITLTQPGGLHARPAARAREAARGLDAHVDVHFEGRKAALQSVVGLLGLGAGEHATIELVATGRDAAKALERVAHELLREAHGEAEEKPARIVSPALAAAAGIARAPLEPNTLAGVCAAPGIAVGTLVRWDDAQIVPPELASGTPAAESRLLDRALAEVDAQLETTVREASRRGAIGEAGIFAVHRVLLEDPALVDAARDLISLGKSAGYAWRETIRAQTAVLADVDDTLLAERAADLRDIDKRVLRALGYASASARELPAEAVLAAEEFTPSDLASLDRERVAALVMARGGATSHAAIIARQLGIPALVAVGDALYAIAQRTQVVVDASAGRLEYAPSALDVERARHERQRLAGVREANRRMSGEAALTRDGHRIEVAANIATLDDARVALDNGADAVGLLRTELMFIHRQAAPTASEHQQSYQSIVDALQGRTAIIRTLDVGADKEVDYLTLPPEPNPALGLRGIRLAQVRPDLLDDQLRGLLAVKPYGSVRILLPMVTDVGELVRIRKRIDDFARAMGRAQAVEVGVMIEVPSAALLADQLAQHADFLSIGTNDLTQYTLAMDRCQADLAAQADGLHPAVLRLVDATVRGAEKHGKWVGVCGALGGDPVAVPVLVGLGVTELSVDPVSVPGIKAQVRRLDYQLCRQRAQDLLALESAQAVRAASREIWPAE
>NZ_CP008777.1|WP_004195337.1|8650_9658_-|SIS-domain-containing-protein
MLNEARESARVVAAQLADTRRVEALAQHLATHAPQVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLKVRGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLPSPLAHACEHPLPLLAGPELSVAATKSYIAMLSIAAQLVAFWQRDAALASALRGLPDALEQAGRLDWSSAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPMELIERDYPLLVFAPPGPEQESLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDPIAAILTFYVMAAGLAPARGRDPDAPRHLHKITETH
>NZ_CP008777.1|WP_004195336.1|9650_10754_-|N-acetylglucosamine-6-phosphate-deacetylase
MLTGNILTAEGWIHGTLEFENGRITTLSGDAADPSNNDAPYILPGFIDLHVHGAGGADVMEGGDAIETIARTHARYGTTSLLATTMTAPRDELMRVVAELGDVARTRTPGGSRVLGVHLEGPYINPGKLGAQPDAAVSAALDEVLKYLSIAPIRVVTLAPEIAGHIEIISEMAARGVRVQLGHSLGTYDDAVAALKHGACGFTHLFNAMSPLHHRNPGIVGAALAHAEYAEIIPDLLHVHPGAIRAALRAIPRLYVVTDSTSATGMPDGEYRLGSQRVTKCLGGVRLADGTLAGSTLTMDQALRNLVSLGLPIADVSSRMSRYAADYLGLADRGRIARGAWADLAVFDRELNLTATFVEGESIVEYA
>NZ_CP008777.1|WP_004543839.1|10852_11587_-|GntR-family-transcriptional-regulator
MDIGWSTLAPDARSDTPLYLQLARNLAGAIHGGAWRAGEALPSERGLSAAAGVSRITARRALALLVEQGLIRRVRGAGSFITPRVADPLSRLVGFTAKMRQRGFAPDSVWLARSLRAASRDELARFGLSPGATVARLERLRRADGVVMAYERSTLPANCVPEPQALEGSLYGYLQSRGLDVVRASQRFRAVNASADVAQWLGLAPGAALLVITRIGYGADRRAIEATETYCRDDYYDFVAELKR
>NZ_CP008777.1|WP_004195334.1|12336_13260_-|LysR-family-transcriptional-regulator
MIDLRRLRYFIVVAEELHFGKAAQRLHLAQPPLTRHISALEGELGLRLFDRSTRSVKLTAEGELFLPHARDVLDAVHRAEIASQRAALGKEGKVALGYTSSVPLCDAFGTLIRNFARSFPDIELSLVEASSAQQGRSIKEGLLDIGIGWKNSFEDYEGCRVKTIAAEPLVVAVSQERALASEASLAVEQLADETFVLFPPGYGSTLDRKAFDLCATAGFTPRRGPSASQMTTMIALVAAGRGVAIVPEAVSTLRKPGVAYVPLTDESALIELVLMWREAGLSLAARSFVEWHKAHVAQRVDGMVGVG
>NZ_CP008777.1|WP_004526041.1|13693_15460_+|AMP-binding-protein
MRDSSPLIERLLAPLAEGRNCRAHGVGTLDESGIERVLSYRQLSEAGLRMSAALNALGARAGDIALVALPATGDYLALLVGCVLSGVVPCTVPPPLKRASGSGPQVLEVACRLYRPRFVFTASAHVAELEAQLRDTGARVIDVGILHAASTGAEPRLALRGAGDTHHIQLTSGSTSHPKAAVISHRNVAANIAGIANACGYSKHAADNTVIWLPLHHDMGLVSLLLHLYYRTSLRLMPSMSFVRNPLGWLRRIAHARSTIAVAPTFALRYCVRRFNAATMDGADFSHLRTFLVGAERVDRATLFDFASTFAPYGFHASALQPCYGMAEATLAVTLHRSFDTPNAPAFTHVIADRIDTATLARHRRAAPAPDGHTGATDTLLAVGAPLDDMAYEIRDAQGRLAAEREAGEIFIRGASVMQGYLPSAGAPAPQPFDAHGWFATGDIGYVSGGQLFILGRKKEIIIIRGTNYFPHEIEETIDSHPAVYKGACIAVGIHDETQGTENLVVLVEAHANHVSRDSRAELQARMQQRLGYCAQRIAFVEPGALPRTTSGKPQRLKARAMFVSGELREIALPPSRRADADRVAPYP
>NZ_CP008777.1|WP_004543793.1|15539_16658_+|hypothetical-protein
MMPDTALPDTPDTPDTPARTFPAAAHADAADLPTLAAQPVRERLAAFGAPPAALDALLRAGATRLLDSDMIIAQPRAHAAARAAERATTPLRYEQSAQTEAVLEQIAHEGLAPHFKPFMRGFSHVMSALFLTPEQDAKVQAYRAAGHHLRFLMSDGGGPALAAWRSTVRVEHGRTRLAIDKVWGIEAHRESIGLVAVRAPGAFMPAAYLVWPEQYRTLERAACGEPFLEGGLQLGNVRGEIETTPEDRLRIGGPNVFNKYLTIVRPYFVRALMAHVGWLAREGRLALSPAHESVRRFVADAARAQSRSSVYGADVVQRVLALKFAANELLGDLVRGGAVRRFDDQRDLLALSKMEGSAYRCYYEIRMGTKRA
>NZ_CP008777.1|WP_004195330.1|16713_16962_+|acyl-carrier-protein
MSTPAAETLPLLAREVAKILHVETVETNVGIGELGIDSLNIVELIVFCEQLYGSIDPETLNITQYTTLAQLDAELRAPQTAA
>NZ_CP008777.1|WP_004185211.1|16994_17882_+|hypothetical-protein
MIELAPIPEPAATALGAARLQLRALAYRRVAAAAGGVGELLEAAAQLGRLLGREALACAGAAAGHAPIDDYVVCSTILSGLLMDDSPHHAAFVGAIASHGPRAADWLTHGYECASWGYVLRETLGKAMHTGTRRLLLQIVDVDIHRFSYWLSHPQWGASGFGVCTLALDVAPGADWPLHLGAAPPAHALAMLGRGFAAFGRERAGVPVAPPFFKEASRRALLKCLGDAPVHPDGHARFGHAFGSDPWISLLLHRCAPGAPAAARAIVGSLALNGYFAIAEIGYDAAARFRLDDTA

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Crispr_ID: NZ_CP008777_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008777_2

431177-431256

Orphan

Consensus_repeat	Method
ACGGAATGGGCCCCGGCATGATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP008777_2

>merge|NZ_CP008777|2|431177-431256|CRISPRCasFinder
ACGGAATGGGCCCCGGCATGATGGGCGGCGGCTACGGGCGCGGAATGATGGGCGGCTACGGAATGGGGCCCGGCATGATG

>NZ_CP008777|2|2|431177-431256|CRISPRCasFinder
ACGGAATGGGCCCCGGCATGATG	GGCGGCGGCTACGGGCGCGGAATGATGGGCGGCT
ACGGAATGGGGCCCGGCATGATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008777.1\|WP_004545687.1\|432205_432754_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004545656.1\|424617_425709_-\|phage-portal-protein	unknown	unknown	gnl\|CDD\|222860
NZ_CP008777.1\|WP_004525830.1\|440126_440474_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_038731640.1\|428735_429830_-\|polyamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270377
NZ_CP008777.1\|WP_004523110.1\|427594_428707_-\|histone-deacetylase	unknown	unknown	gnl\|CDD\|212521
NZ_CP008777.1\|WP_004545671.1\|426107_426572_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004200731.1\|423780_424263_+\|DUF2778-domain-containing-protein	unknown	unknown	gnl\|CDD\|378506
NZ_CP008777.1\|WP_004545670.1\|434484_436098_-\|glutamate--cysteine-ligase	unknown	unknown	gnl\|CDD\|235001
NZ_CP008777.1\|WP_004189258.1\|426708_427584_-\|N-carbamoylputrescine-amidase	unknown	unknown	gnl\|CDD\|274553
NZ_CP008777.1\|WP_004545654.1\|436256_437198_-\|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl\|CDD\|223200
NZ_CP008777.1\|WP_004197759.1\|439356_439911_-\|YaeQ-family-protein	unknown	unknown	gnl\|CDD\|377782
NZ_CP008777.1\|WP_038731643.1\|422238_423243_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369676
NZ_CP008777.1\|WP_004533510.1\|442196_442352_-\|lipoprotein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004545645.1\|429972_430941_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP008777.1\|WP_004531075.1\|433017_434466_+\|RNA-polymerase-sigma-factor-RpoD/SigA	unknown	unknown	gnl\|CDD\|274108
NZ_CP008777.1\|WP_004523107.1\|424259_424544_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004197761.1\|438690_439107_+\|lactoylglutathione-lyase	unknown	unknown	gnl\|CDD\|319916
NZ_CP008777.1\|WP_154218334.1\|421768_422137_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004524603.1\|440959_441520_-\|spermidine-N1-acetyltransferase	unknown	unknown	gnl\|CDD\|237916
NZ_CP008777.1\|WP_004523120.1\|437194_438289_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	unknown	unknown	gnl\|CDD\|185333

Protein	Function_ID	Function_description	E-value
NZ_CP008777.1\|WP_004197759.1\|439356_439911_-\|YaeQ-family-protein	gnl\|CDD\|377782	pfam07152, YaeQ, YaeQ protein. This family consists of several hypothetical bacterial proteins of around 180 residues in length which are often known as YaeQ. YaeQ is homologous to RfaH, a specialized transcription elongation protein. YaeQ is known to compensate for loss of RfaH function.	3.23549e-104
NZ_CP008777.1\|WP_004545656.1\|424617_425709_-\|phage-portal-protein	gnl\|CDD\|222860	PHA02536, Q, portal vertex protein; Provisional.	0
NZ_CP008777.1\|WP_004523120.1\|437194_438289_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	gnl\|CDD\|185333	PRK15435, PRK15435, bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada.	8.19665e-122
NZ_CP008777.1\|WP_004523110.1\|427594_428707_-\|histone-deacetylase	gnl\|CDD\|212521	cd09996, HDAC_classII_1, Histone deacetylases and histone-like deacetylases, classII. This subfamily includes bacterial as well as eukaryotic Class II histone deacetylase (HDAC) and related proteins. Deacetylases of class II are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. Included in this family is a bacterial HDAC-like amidohydrolase (Bordetella/Alcaligenes species FB18817, denoted as FB188 HDAH) shown to be most similar in sequence and function to class II HDAC6 domain 3 or b (HDAC6b). FB188 HDAH is able to remove the acetyl moiety from acetylated histones, and can be inhibited by common HDAC inhibitors such as SAHA (suberoylanilide hydroxamic acid) as well as class II-specific but not class I specific inhibitors.	1.0559e-172
NZ_CP008777.1\|WP_004200731.1\|423780_424263_+\|DUF2778-domain-containing-protein	gnl\|CDD\|378506	pfam10908, DUF2778, Protein of unknown function (DUF2778). This is a bacterial family of uncharacterized proteins.	2.57059e-50
NZ_CP008777.1\|WP_004545670.1\|434484_436098_-\|glutamate--cysteine-ligase	gnl\|CDD\|235001	PRK02107, PRK02107, glutamate--cysteine ligase; Provisional.	0
NZ_CP008777.1\|WP_004189258.1\|426708_427584_-\|N-carbamoylputrescine-amidase	gnl\|CDD\|274553	TIGR03381, putative_carbon-nitrogen_hydrolase, N-carbamoylputrescine amidase. Members of this family are N-carbamoylputrescine amidase (3.5.1.53). Bacterial genes are designated AguB. The AguAB pathway replaces SpeB for conversion of agmatine to putrescine in two steps rather than one. [Central intermediary metabolism, Polyamine biosynthesis].	0
NZ_CP008777.1\|WP_038731643.1\|422238_423243_+\|hypothetical-protein	gnl\|CDD\|369676	pfam08065, K167R, K167R (NUC007) repeat. This family represents the K167/Chmadrin repeat. The function of this repeat is unknown.	0.00519166
NZ_CP008777.1\|WP_004545645.1\|429972_430941_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.41187e-70
NZ_CP008777.1\|WP_004531075.1\|433017_434466_+\|RNA-polymerase-sigma-factor-RpoD/SigA	gnl\|CDD\|274108	TIGR02393, RNA_polymerase_sigma_factor_RpoD, RNA polymerase sigma factor RpoD, C-terminal domain. This model represents the well-conserved C-terminal region of the major, essential sigma factor of most bacteria. Members of this clade show considerable variability in domain architecture and molecular weight, as well as in nomenclature: RpoD in E. coli and other Proteobacteria, SigA in Bacillus subtilis and many other Gram-positive bacteria, HrdB in Streptomyces, MysA in Mycobacterium smegmatis, etc. [Transcription, Transcription factors].	2.83254e-88
NZ_CP008777.1\|WP_004545654.1\|436256_437198_-\|DNA-3-methyladenine-glycosylase-2-family-protein	gnl\|CDD\|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	8.158e-54
NZ_CP008777.1\|WP_004197761.1\|438690_439107_+\|lactoylglutathione-lyase	gnl\|CDD\|319916	cd07253, GLOD5, Human glyoxalase domain-containing protein 5 and similar proteins. Uncharacterized subfamily of VOC family contains human glyoxalase domain-containing protein 5 and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.46868e-30
NZ_CP008777.1\|WP_038731640.1\|428735_429830_-\|polyamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	8.34781e-150
NZ_CP008777.1\|WP_004524603.1\|440959_441520_-\|spermidine-N1-acetyltransferase	gnl\|CDD\|237916	PRK15130, PRK15130, spermidine N1-acetyltransferase; Provisional.	7.47948e-86

>NZ_CP008777.1|WP_004545645.1|429972_430941_+|LysR-family-transcriptional-regulator
MRRIDLLSALETFVCAVEEGSLSQAARRLAKTPSAVTKAIAGLEATLGVQLLERTTRRLALTESGRLYLATATDVLRRLADGARQLSERDDEPRGLLRVTAAHSFGHAILAPLCAPFAQAFPRVRIELSLSDHYVDIVGEGFDLALRMGNYDLPSQIVKPIGSNRGLLCASPGYLARRGRPTAPADLARHDCVIYRHPTLANTWTFERGGVRARLEPKGPLVTDDYGLALAAALGGAGVLPCPQWSVVDALEAGRLVPLLVDWRFESASFGEDRICAAYPSSRRGSTKIRRLVERVQARLADSEARVAHVLGDALCADLARR
>NZ_CP008777.1|WP_038731640.1|428735_429830_-|polyamine-ABC-transporter-substrate-binding-protein
MKRIAWLAAVLASLACAAARAADGNVLNIYNWAEYFAPDTIAGFEKETGIKVRLDVYDSNEALQTKLTTGNSGYDLVFPSNDFLARQIQAGLYRKLDKSRLPNLTNLDPAIVARAAEVDPGNQYSVPYMQGTFGLGLNVAKVKQALGGPLPVNTLELIFNPAYAAKLERCGIAFNDAGSEVFPLALRYIGRDPNTTDPRDYEAALDMMKKIRPTIRQFIATPVMNDLATGDVCVVTGYSGAVLVAARRAAEAKNGQQIVYSLPSAGAPFWFDSMAIPKGAAHADHALRFIDYILRPDVVAKISNKVMYPNPNRVATPLVDRRLTANPAIYPDAATMRTLWVKRPMPPQAMRMQTRYWTRFKTGY
>NZ_CP008777.1|WP_004523110.1|427594_428707_-|histone-deacetylase
MIPTGLLFDPAFLSHRQGDLVYVVPHGTLNLGEHFDSPLRLAYTKQLLDAVGMTERLTRVAFARATDEQLLRVHRPEYLRQLAEACAVAGEQVVRLGDDAAGSASTEDVARLAAGAACAAVDAVMTGPLRQAYALIRPSGHHAGADFAMGYCYYNNVAIAARHAQAAHGVERVAIVDWDVHHGNGTQQAFYDDPSVLFVSLHEAANFPVDGGEARETGGGAGAGYNANVPLPSGTGDAGYRHAFDELVLPLVEAFAPQLILVSAGQDANAFDPLGRMRVQRDGFRHMARALRQAAGGACGGRIVMLQEGGYSLPYLPIATLGVLEGLVGWNAPFDDPHQFVQYPLGEGERAAVKAARAALAPYWPTLHRS
>NZ_CP008777.1|WP_004189258.1|426708_427584_-|N-carbamoylputrescine-amidase
MRKTTVAVTQMACDWNVDANLSRAERLVRDAAARGAQIVLLQELFETPYFCIDQHPAHLALAQPYEGHPWLMRFASLARELGVVLPVSFFERAGQTQFNSVAIFDADGRALGIYRKTHIPDGPGYTEKYYFTPGDTGFRVWDTAYGRIGVGICWDQWFPECARAMALAGAELLLYPSAIGSEPHDASIDSRAHWRNAQRGHAAANLMPVAASNRVGVERGASGEIVFYGSSFIAGADGEMIVECDRHGEAIATAEFDLDALAYRRRGWGVFRDRRPECYRALSEGAADRVR
>NZ_CP008777.1|WP_004545671.1|426107_426572_+|hypothetical-protein
MEFRPIKESDLGSTYDIRFSVTENRILPHQIHLLDRDRVLEQLRSGFGVLAIEGDAAVGYCTAAGLGGPGKRSWRTAPKHCHAGPRRLRERAALAAAAPMAARSRPRGCVTCKAPSAERRSPSETSCASARTGRRAPFGRFSAFAAHRQAGRRH
>NZ_CP008777.1|WP_004545656.1|424617_425709_-|phage-portal-protein
MSSWRRRASTTAPSACSNVTSSAATTLRNRPRQIRAPARAEVFTFDDPTPVMNRAEILDYVECWSNGEWFEPPVSFAGLAKSFRASTHHSSALFFKANVLASTFRPHRWLSRHAFERWALDFLTFGNGYLERRRNMVGGTLRLEPALAKYVWRKADFSGFVYVNGWQERHEFEPDSVFQLVRPDINQEVYGLPEYLSSLHSAWLNESSTLFRRKYYENGSHAGFILYMTDAAQKQDDVDNMRDALKNAKGPGNFRNVFMYAPGGKKDGIQLIPVSEVAAKDEFFNIKNVTRDDLLAAHRVPPQLLGIVPSNSGGFGTPDTAARVFGRNEIRPLQARFAELNDWLGDEVVRFDDYEIPPAPVAA
>NZ_CP008777.1|WP_004523107.1|424259_424544_+|hypothetical-protein
MKTIGRILLALVLTWPLLTGISSLPLLTHWFANGGEGWNALSPVFRALGSDGGEQNEEIFVGILLVISFVLALVLSFALFGLVDRLRHSTDRRA
>NZ_CP008777.1|WP_004200731.1|423780_424263_+|DUF2778-domain-containing-protein
MPAECTFVLNRSRLSTLTCPGFGSVPAFSGNGRYINDPGSTAVADKGPLPAGVYYIIDRQSGGHLGWFRDTVMDAALNTYRAEWFALYRIDGQIDDWTIVNGIRRGHFRLHPVGRLGESDGCITLTSRGQFDKLRAFLKAQPTTQVPGTSFRAYGKVTVK
>NZ_CP008777.1|WP_038731643.1|422238_423243_+|hypothetical-protein
MAQKKKVVYFLGAGASFGAGAKATVQAGHQLPIPTQATFWPTFLRFCKSQKNRARIESFLFRYFLGYGKTPVRTPAAKRRHLLTSIDVEEVFTFLSERTRAPSTSTQLRTYALQIWGALAEEIGLVFSRFNANSATKAIYKDFLKHHFRRFDTVVSFNYDTIFENSLPARRSARYVGLRDSAGTIPLLKPHGSVNWVQADDGTITVGNPVGPAVIVAPTHLKFISDPDQKEVQHPGYLDQAHEIQKIWAEMEREMRFARSLVFIGYSFPVADLYFASVLRSVLADRDTTPNIVIVNPDAVAISERLLRRFPLVTVSRFFDLAQFIRAGRAVIAQ
>NZ_CP008777.1|WP_154218334.1|421768_422137_+|hypothetical-protein
MLLLPAANSDAPLPPEHCLRRFLYAPPPFKINALRDSQSANPRLIKVNPGHPSTPELSFHCTAQAATSSATCPTNPPRTAPLTRSFAAIDYKAPEIPSTFNNLDKYRVSKTIDCKGFGALSG
>NZ_CP008777.1|WP_004545687.1|432205_432754_+|hypothetical-protein
MEEAYARRALLLHLGSVLQILSRLEGAPDNQSIETLLAANGMLADVPLVEYVVQDMTVREFSARALRAFCLWPQLLLEDPLDCAALALPVRKHLFAGNDAGWKAYAATLREVSPGFDTARSYAAEPHEAEFDLADERDAETGDGPVERDDEADDDGRLRERAAASVESATPAGAPVRRESYE
>NZ_CP008777.1|WP_004531075.1|433017_434466_+|RNA-polymerase-sigma-factor-RpoD/SigA
MKVSARELRYEQGIDRLLELAGARDDTEYADVADEFASAPSSAFAHDLGEPDSLDHQASDESAGAGSFGDKPTRPAHGDTDVDTDWRDDDAPPSGSNDAAPVDTTASTDPLALFVRRMHAVPLLTHAQEIALAAEIEAGREQVLQALAEALDRLDLASLPADPALGRARAALQRARARGDEGARAFARARTAAYAALAAHGWPSAEVDAVRRAMRRLPTSPEKSDAGAQRAFADGEARISAATARMAEANLRLVLSIARKYASRGLDLADLLQEGNLGLLRAIEKFEHRRGFKFSTYATWWIRQAISRAIADRARTIRVPVHVGDEARRVRKAADRIERRSGVSASLAELSEATGLPAERLRAVLTLPREPRSLNAPLGDDDQAEFGDIVEDTSTPSLFDALAHGQMCDVVTSLLKTMSAQEADILRRRFGIGGDEPWSYEQIAARAGVSREQVRRIEKRALQTLRVTAEACNAHDFLDVQP
>NZ_CP008777.1|WP_004545670.1|434484_436098_-|glutamate--cysteine-ligase
MPNNMTSRQTDLLQQRLAVLSTSPTREQLPDGLRGIEKESLRVTRDGMIAFTPHPRALGSALTHPSLTTDYSEALVELITPAERDAATTLERLDELHRYVYASLGDEMLWTDSMPGLLPADDEIPIADYGTSNIGRLKTVYRRGLAYRYGRTMQCIAGIHYNYSLSEEVWRRLHAEEGSTAGIVDYQSERYLALIRNFRRTSWLLMYLFGASPALDAGFLRGRAHKLDTFDAATLYRPHATSLRMSDLGYSNTTAQAALQADYNTLSGYLDALSKAVSEPYPPYEAIGTHRDGEWIQINTNVLQIENEFYSTIRPKRVTYSGERPLHALASRGVQYIEVRCLDIDPFEPTGIALDTARFLDAYLLVCALDESAPLTCDAYRESNANFGRVTMEGRKPGLELTRDGAAVPMRAWADEIFAQIEAAGRVLDDIRGDDAHARAIAAQRAKLDDPELTSSARVLRAMRENGQSFLEFARAQSAAHAAYFHGRPLDEAATRDARALAERSLAEQAELEGKNAGSFDAFVAAYRAYTLNRFSV
>NZ_CP008777.1|WP_004545654.1|436256_437198_-|DNA-3-methyladenine-glycosylase-2-family-protein
MSAAVEPAAVRPDSVVLELPFKSPYDWPRVLRFFAGRAIPGVEAVGDGAYRRTVDHHGAIGTLTVRKHPRKRCLVALVEGDAARHADAAFAARLSTMFDLQADPAAIGAHLARDAWFAPLVGAAPGLRVPGAWSGFELIVRAIVGQQVSVKAATTIVGRLVERAGERLAPHAPGAIGWRFPEPAALAACDLSRIGMPGKRAAALQGVARAVAAGDVPLEAYASDPAGVRAALLALPGIGPWTVEYVAMRAWRDADAWPATDLVLMQAIVARDPALDRPASQRLRADAWRPWRAYAAMHLWNEIADRAGSARGG
>NZ_CP008777.1|WP_004523120.1|437194_438289_-|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada
MKQPPYPTDDARWAALVARDVDADGAFCYAVKTTGVFCRPSCASRLPRRENVSFFADTGAARAAGYRPCKRCRPEGLPRELDIVNRACAVLDAHRQDRFTLAQLSDAVHVSPFHLQRLFKRVVGVSPRQYQAAQRGAALRDALQSGAAVTRAAVDAGFNSPSRLYESVPRELGMSPSAFRRKGAGLKIDYATADTRLGVVLVAATSKGICKIAFGDAAAPLVDELRTGFANAQIAESPERIAPFIAQVDAYLNGTRRRFELPLDLAATEFQQRVWDALRRIPYGETRSYTQIAEALGAPRAVRAVASACASNPVALAIPCHRVVQKGGSLAGYRWGLPRKAALLDAEAQRAAGESVESAVDHAA
>NZ_CP008777.1|WP_004197761.1|438690_439107_+|lactoylglutathione-lyase
MKFHIHEIDHVVLRAADLAAMTRFYCDVLGCHVEKEQRELGLVQLRAGRSLIDLLAVGAPIDRAGSGAPGKGRNMDHLCLRVEPFDAAALRTHLAAHGARPGDEARRYGADGYGPSLYLFDPEGNMVELKGPPEAVAP
>NZ_CP008777.1|WP_004197759.1|439356_439911_-|YaeQ-family-protein
MALKSTIYKAELQIADMDRHYYADHSLTVARHPSETDERMMVRIAAFALFAHERLEFCKGLSDTDEPDLWQKDLTGAIEVWIDVGQPDERRIAKASGRAGRVNVIAYGGRTSDIWWQGARGKVERLRNVQVTTLADGVAAALGGLAERTMRLQCTIQDGAAWLSSATHDPVAIEWTTLKAREDA
>NZ_CP008777.1|WP_004525830.1|440126_440474_-|hypothetical-protein
MLKRTGLFLALTGGIVAFSVAQANGDASLKPQQEIQLTKNAWGCLSKDNLDSVLNHERDGKAQAKQQYFDDYRCLSVPEGQRFRVVSVDKGDVQFVSAENSDQQGLWTDARFIKQ
>NZ_CP008777.1|WP_004524603.1|440959_441520_-|spermidine-N1-acetyltransferase
MQIQNEQHTLALRPLERQDLRFVHELNNDAKIMRYWFEEPYETFTELSQLYDQHVHDQRERRFVAFDSDGELVGLVELIELDYIHRRGEFQIIIAPNRQGRGFATRATRLAVEYAFKVLNLRKLYLIVDKSNVAAIRVYEKCGFKHEAELIEEFFGNGQYHNALRMCIFQRDYFAAQPGAELHARE
>NZ_CP008777.1|WP_004533510.1|442196_442352_-|lipoprotein
MKKIIIALAVSAGILSGCAVYVPDQPGVIVAPQGGPGNGFCPPGQAKKGNC

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Crispr_ID: NZ_CP008777_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008777_3

2295521-2295732

Orphan

Consensus_repeat	Method
CGCAAACCGCAAACCGCAAACCGCAAACCGCAAACC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP008777_3

>merge|NZ_CP008777|3|2295521-2295732|CRISPRCasFinder
CGCCAAACGCCAAACGCCAAACGCCAAACACGAAACACGAAACACGAAACACGAAACACGAAACGCCAAACGGTAAGCAGCGAGTGCCAAGCGGCAATCGCGAAGGTTGAAGGGAAAGGGCGATGGTCGCAAACCGCAAACCGCAAACCGCAAACCGCAAACCGCAAACCGCAAACCGCAAACCGCAAACCGCAAACCGCAAACCGCAAACC

>NZ_CP008777|3|3|2295521-2295732|CRISPRCasFinder
CGCCAAACGCCAAACGCCAAACGCCAAACACGAAAC	ACGAAACACGAAACACGAAACACGAAACGCCAAACGGTAAGCAGCGAGTGCCAAGCGGCAATCGCGAAGGTTGAAGG
GAAAGGGCGATGGTCGCAAACCGCAAACCGCAAACC	GCAAACCGCAAACCGCAAACCGCAAAC
CGCAAACCGCAAACCGCAAACCGCAAACCGCAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008777.1\|WP_004197460.1\|2294714_2295260_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004550362.1\|2306049_2306694_+\|OmpW-family-protein	unknown	unknown	gnl\|CDD\|225589
NZ_CP008777.1\|WP_004544309.1\|2288535_2289462_+\|sugar-kinase	unknown	unknown	gnl\|CDD\|238571
NZ_CP008777.1\|WP_004544391.1\|2290758_2291337_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
NZ_CP008777.1\|WP_004521351.1\|2287141_2288533_+\|30S-ribosomal-protein-S12-methylthiotransferase-RimO	unknown	unknown	gnl\|CDD\|237838
NZ_CP008777.1\|WP_004192676.1\|2285946_2286519_+\|polyhydroxyalkanoate-synthesis-repressor-PhaR	unknown	unknown	gnl\|CDD\|227682
NZ_CP008777.1\|WP_004531382.1\|2302200_2302836_-\|eIF4A-inactivating-lethal-factor-BLF1	unknown	unknown	gnl\|CDD\|375316
NZ_CP008777.1\|WP_004191593.1\|2304786_2305977_+\|nitronate-monooxygenase	unknown	unknown	gnl\|CDD\|224981
NZ_CP008777.1\|WP_004191494.1\|2306819_2307023_-\|DUF1289-domain-containing-protein	unknown	unknown	gnl\|CDD\|225850
NZ_CP008777.1\|WP_004527142.1\|2303151_2304588_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143456
NZ_CP008777.1\|WP_004193217.1\|2293084_2293930_-\|phosphoserine-phosphatase-SerB	unknown	unknown	gnl\|CDD\|319803
NZ_CP008777.1\|WP_004534623.1\|2300037_2300418_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008777.1\|WP_004191253.1\|2295885_2296704_-\|iron-export-ABC-transporter-permease-subunit-FetB	unknown	unknown	gnl\|CDD\|377092
NZ_CP008777.1\|WP_004527150.1\|2283762_2284944_+\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|180261
NZ_CP008777.1\|WP_004544384.1\|2297529_2300004_+\|AsmA-family-protein	unknown	unknown	gnl\|CDD\|225529
NZ_CP008777.1\|WP_004521353.1\|2289557_2290742_+\|acetyl-CoA-C-acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|181625
NZ_CP008777.1\|WP_004544464.1\|2291636_2292821_+\|cystathionine-beta-lyase	unknown	unknown	gnl\|CDD\|180810
NZ_CP008777.1\|WP_004192911.1\|2296700_2297396_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226970
NZ_CP008777.1\|WP_004538238.1\|2300461_2302054_+\|ABC-F-family-ATPase	unknown	unknown	gnl\|CDD\|237894
NZ_CP008777.1\|WP_004193701.1\|2285069_2285810_+\|3-ketoacyl-ACP-reductase	unknown	unknown	gnl\|CDD\|171822

Protein	Function_ID	Function_description	E-value
NZ_CP008777.1\|WP_004544384.1\|2297529_2300004_+\|AsmA-family-protein	gnl\|CDD\|225529	COG2982, AsmA, Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane].	6.56687e-85
NZ_CP008777.1\|WP_004550362.1\|2306049_2306694_+\|OmpW-family-protein	gnl\|CDD\|225589	COG3047, OmpW, Outer membrane protein W [Cell envelope biogenesis, outer membrane].	2.18065e-48
NZ_CP008777.1\|WP_004544309.1\|2288535_2289462_+\|sugar-kinase	gnl\|CDD\|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	7.35544e-95
NZ_CP008777.1\|WP_004544391.1\|2290758_2291337_+\|hypothetical-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.0058489
NZ_CP008777.1\|WP_004521351.1\|2287141_2288533_+\|30S-ribosomal-protein-S12-methylthiotransferase-RimO	gnl\|CDD\|237838	PRK14862, rimO, 30S ribosomal protein S12 methylthiotransferase RimO.	0
NZ_CP008777.1\|WP_004192676.1\|2285946_2286519_+\|polyhydroxyalkanoate-synthesis-repressor-PhaR	gnl\|CDD\|227682	COG5394, COG5394, Uncharacterized protein conserved in bacteria [Function unknown].	4.78088e-68
NZ_CP008777.1\|WP_004531382.1\|2302200_2302836_-\|eIF4A-inactivating-lethal-factor-BLF1	gnl\|CDD\|375316	pfam17752, BLF1, Burkholderia lethal factor 1. This family includes members such as BLF1 (Burkholderia lethal factor 1) also known as BPSL1549. BLF1 is a potent toxin from Burkholderia pseudomallei causing melioidosis. BLF1 interacts with the human translation factor eIF4A causing deamidation of Gln339 to Glu. Thereby, reducing endogenous host cell protein synthesis and triggering increased stress granule formation, which is associated with translational blocks. Structural analysis of BLF1 revealed an alpha/beta fold comprising a sandwich of two mixed beta-sheets surrounded by loops and alpha-helices, where the beta-sheet core of the catalytic pocket is structurally similar to that of the deamidase domain of CNF1 pfam05785.	4.52152e-141
NZ_CP008777.1\|WP_004191593.1\|2304786_2305977_+\|nitronate-monooxygenase	gnl\|CDD\|224981	COG2070, COG2070, Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only].	8.22416e-62
NZ_CP008777.1\|WP_004191494.1\|2306819_2307023_-\|DUF1289-domain-containing-protein	gnl\|CDD\|225850	COG3313, COG3313, Predicted Fe-S protein [General function prediction only].	4.88343e-20
NZ_CP008777.1\|WP_004527142.1\|2303151_2304588_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143456	cd07138, ALDH_CddD_SSP0762, Rhodococcus ruber 6-oxolauric acid dehydrogenase-like. The 6-oxolauric acid dehydrogenase (CddD) from Rhodococcus ruber SC1 which converts 6-oxolauric acid to dodecanedioic acid, and the aldehyde dehydrogenase (locus SSP0762) from Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 and other similar sequences, are included in this CD.	0
NZ_CP008777.1\|WP_004193217.1\|2293084_2293930_-\|phosphoserine-phosphatase-SerB	gnl\|CDD\|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	6.40285e-86
NZ_CP008777.1\|WP_004191253.1\|2295885_2296704_-\|iron-export-ABC-transporter-permease-subunit-FetB	gnl\|CDD\|377092	pfam03649, UPF0014, Uncharacterized protein family (UPF0014).	5.39878e-102
NZ_CP008777.1\|WP_004527150.1\|2283762_2284944_+\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP008777.1\|WP_004521353.1\|2289557_2290742_+\|acetyl-CoA-C-acyltransferase-family-protein	gnl\|CDD\|181625	PRK09051, PRK09051, beta-ketothiolase BktB.	0
NZ_CP008777.1\|WP_004544464.1\|2291636_2292821_+\|cystathionine-beta-lyase	gnl\|CDD\|180810	PRK07050, PRK07050, cystathionine beta-lyase; Provisional.	0
NZ_CP008777.1\|WP_004192911.1\|2296700_2297396_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226970	COG4619, COG4619, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	9.51517e-66
NZ_CP008777.1\|WP_004538238.1\|2300461_2302054_+\|ABC-F-family-ATPase	gnl\|CDD\|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
NZ_CP008777.1\|WP_004193701.1\|2285069_2285810_+\|3-ketoacyl-ACP-reductase	gnl\|CDD\|171822	PRK12938, PRK12938, 3-ketoacyl-ACP reductase.	1.17195e-175

>NZ_CP008777.1|WP_004197460.1|2294714_2295260_+|hypothetical-protein
MSQRILSPLVASCAAAALLSAFAAHAAPPIKGSVLGGNDGQLQYTVKVDSKQFGTMQETRKIRSGETDDYNWKSVPPSGAVPMPDACPNADTLPRDANGAMVRQAQVRLAPAVDSKGVANVQLSFQASAPSGTKKVTVNGKALQCPNVVAVSQVKWLSIPTGGSKSITMRDGTKITVSIKR
>NZ_CP008777.1|WP_004193217.1|2293084_2293930_-|phosphoserine-phosphatase-SerB
MTTNLVVQSTAPLSDAHHKPLAALAHGARVVALDAQSIRIERANPAQRADIDAYCGTHALDYAFVDAARKLADFGLVAMDMDSTLITIECIDEIADFCGLKAEVSAITEAAMRGEIKDFNESLTRRVALLAGLEASALERVYEERLRLSPGAESMLAGVKAAGLKTLLVSGGFTFFTERLKARLGLDFAHSNTLEIVDGKLTGKVVGEIVNADVKARAVRETCAALGIEPARAIVIGDGSNDLKMMAAGGFSIAFRAKPIVRSAASAAFDHVGLDGLLRLF
>NZ_CP008777.1|WP_004544464.1|2291636_2292821_+|cystathionine-beta-lyase
MTASIPKRALQTRVVQPDDRIPAGFESFVVPVARASTVVFPDLATMRNLDWRQDGQWRYGLHATPTSLALAQRLAEIEGGAHALLQPSGLCAITNVYFGLVKEGDDVLIPDNAYGPNGDFGKWLAKDFGITARFYDPMIGAGIVDLIQPNTRIVWLEAPGSVTMEVPDVRAITAVARARGIVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADGELHAKLKLARMRLGIGVSADDCSLVLRGLPSMQARFDAHSRSALSLARWLKTRAEIATVLHPQLPDCPGHDTFMRDFTGAGGLFSVVFDERYDAAQVDRFVEALELFAIGWSWGGACSLAMPYDVQSMRTGKWPHRGTLVRFYVGLEDEADLRADIERALTSALA
>NZ_CP008777.1|WP_004544391.1|2290758_2291337_+|hypothetical-protein
MKLITAIRGAALAAALATAAGLAFAQSSSARAAAAPGAADAAPAAAGQADAPPPAVPLKPNPAYARLPRYEGTVGGRPVVVRLGPKTDEPGVHGECQYLDTGAVILLAGDRDGDTLEIEESDDGTNITGVWIGRFDPSGGLSADRMNADQSDPLPVALHPAGAQSASAAVGAPQAGARGQSVGGVSNLRTGE
>NZ_CP008777.1|WP_004521353.1|2289557_2290742_+|acetyl-CoA-C-acyltransferase-family-protein
MQREVVVVSGVRTAIGDFGGSLKDFAPTELGARVVREVLSRAQVSGDEVGHVVFGNVVHTEPKDMYLARVAAINGGIAQHAPALTVNRLCGSGLQAIVSAAQNVLLGDADIAVAGGAENMSRAPYSVPAARFGQRMGDAKLVDMMIGALNDPFQSIHMGVTAENVAAKYGITRDAQDALALESHRRASHATKSGYFKDQILPIEIASRKGTVVFDADEHVRHDASLDDFTKLKPVFAKENGTVTAGNASGINDAAAAVVLMERGVADKRGAKPLARLVSYAHAGVDPAYMGIGPVPATKKALERAGITVADLDVIEANEAFAAQACAVSNALGLDPAKVNPNGSGISLGHPIGATGALITVKALYELQRIGGRYALVTMCIGGGQGIAAVFERL
>NZ_CP008777.1|WP_004544309.1|2288535_2289462_+|sugar-kinase
MPATFPDVLALGEAMVEFNQARPGEPNYLQGFGGDTSNFCIAAARQGARAGFVSAVGGDHFGRLLLDLWRGERVDTSYVRVDDGAPTGVYFVSHGEHGHAFDYLRAGSAASRYAIRDLPLDALAAARFVHLSGVSLAISTSACDAAFAAIAHARANGARVSFDTNLRLKLWPLPRARAVMTEALRHTDVCLPSWDDVTALTGLDERDAIVDALLALGPRVVALKLGRKGAYVATPGERRVVPGFVVDALDATGAGDCFGGAFVARLAAGDDPFSAARYANAAAALSTQGFGAVAPIPSRDAVERLLGA
>NZ_CP008777.1|WP_004521351.1|2287141_2288533_+|30S-ribosomal-protein-S12-methylthiotransferase-RimO
MENSLKSSGKPLAAPKVGMVSLGCPKALVDSEQIITQLRAEGYEISGTYDGADLVVVNTCGFIDEAVQESLDAIGEALAENGKVIVTGCLGAKKSASGSGLIAEVHPKVLAVTGPHAVGEVMQAVHSHLPKPHDPFVDLVPAAGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGELVSRPVAEVMLEAENLFKSGVKELLVISQDTSAYGVDVKYRTGFWNGRPLKTRMTELVGALGELAAQYGAWVRLHYVYPYPHVDEIIPMMAQGPLKGHVLPYLDVPFQHAHPEVLKRMKRPANAERVLERVQKWREICPDLTIRSTFIAGFPGETDAQFETLLDFIREAELDRVGCFAYSPVEGASANALDGALPDDVREARRARFMEVAEEVSAARIARKVGKTLKVLIDEVNAEGGIGRTAADAPEIDGVVYVEPAAKASKRYKVGEFVSVKITGADGHDLWGEV
>NZ_CP008777.1|WP_004192676.1|2285946_2286519_+|polyhydroxyalkanoate-synthesis-repressor-PhaR
MTTTKKTGERLIKKYPNRRLYDTETSTYITLTDVKQLVLEQEDFKVIDAKSSEDLTRSILLQIILEEESGGVPMFSSSMLSQIIRFYGHAMQGMMGTYLEKNIQAFIDIQSKLADQSKNLYENNAMNPEVWSQFMNMQAPMMQGMMTSYIEQSKNMFVQMQEQMQNQAKTMFSSFPFKPATPPGSEPEKK
>NZ_CP008777.1|WP_004193701.1|2285069_2285810_+|3-ketoacyl-ACP-reductase
MSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADFSLNGGLHMG
>NZ_CP008777.1|WP_004527150.1|2283762_2284944_+|acetyl-CoA-C-acetyltransferase
MTDVVIVSAARTAVGKFGGSLAKIAAPELGASVIRAVLERAGVKPEQVSEVILGQVLTAGSGQNPARQALIAAGLPNAVPGMTINKVCGSGLKAVMLAANAVVAGDAEIVVAGGQENMSAAPHVLPGSRDGFRMGDAKLVDSMIVDGLWDVYNKYHMGITAENVAKEYGITREAQDQFAALSQNKAEAAQKAGRFDDEIVPIEIPQRKGEPLRFATDEFVRHGVTAESLASLKPAFAKEGTVTAANASGINDGAAAVLVMSAKKAEALGLEPLARIKAYANAGVDPSVMGMGPVPASRRCLERAGWSVGDLDLMEINEAFAAQALAVHKQMGWDTSKVNVNGGAIAIGHPIGASGCRILVTLLHEMLKRDAKRGLASLCIGGGMGVALALERP
>NZ_CP008777.1|WP_004191253.1|2295885_2296704_-|iron-export-ABC-transporter-permease-subunit-FetB
MNTPLQDLSLVDVGIAAALVAINGAISVALSLGLGRKLAWAAARTVVQLLAIGYVLGWVFGHPRWYVVLPLVALMTLIAGFAGAARGKRTYAGQRADSVLSIWASSWFVAAIGLFVVIRIHPWYAPQYAIPILGMILGNTLTGVSLGVERMMEELTARRDRVETALALGATRWEAAQDAARQAVRAGMLPTLNQMAVVGVVSLPGMMTGQVLAGQSPLQAVRYQIVIMFLIAAASALGTVGAVLSTYRRLFSAEHRFLASRLVERERTANGG
>NZ_CP008777.1|WP_004192911.1|2296700_2297396_-|ATP-binding-cassette-domain-containing-protein
MTADVLIEARQLARRDAARGKTLLAPSDFALAAGERIALTGPSGSGKSVFLRALALLDPIDGGELLWRGTRVPRPAIPRYRRSVAYVRQRPATAEGTVEDLLRYPYSLAVYRDARFDAARVARLAAQAGRGDDFLRKAASELSGGEAQIAALLRVLQLDPDVLLLDEPTSALDPDSTRAIEALVAAWFDAAPAARAYLWISHDPAQAARVGRRRLTMRAGVLGDAATQDAR
>NZ_CP008777.1|WP_004544384.1|2297529_2300004_+|AsmA-family-protein
MALTRTLGKTAAWIVGIFAVLTAAVGVFIFTFDWNRAKPWINEQASASIGRPFEIRGDIKVGWRRPDGETGWRAWVPWPVFSASRIVIGNPPWAKAPNFATLDEARFELAVLPLLAHEVVIPTIELVNPALDIERLADGRNNWTFEFKQSAGPSPWKVQLRDFGFAKGTVVYRDAITKADLSVAVDTLGQPIPLGDVLRQQEETSRAASAQRVGKRGAAQLAAKAQAQIASDASAASAAGAPNASGAAAASGASGVNAAASAAKVSGNDRSRAARATAGASAASKPAAAASGGSAAAVAAGKAPAAGAGGAVASASASAASSASAVSTSAAVSGASGASAASAAEQRSAGPTYAFGLTVKGRYKGVPIDGTGKVGGVLSLRDASRPFPLQADVKAGDTRLAIVGTLTDPVHLAAIDLRLWLQGSSMSHLYPLTGVTLPDTPPYATEGRLIGRFKRAASTFRYENFNGRVGGSDLRGTLVYQQRAPRPLLSGELVSNLLQFSDLAPIIGADTAASKARRGDTTKQPPGRVLPVETFRTDRWRALDADVKFTGRKLIKSAALPISDLYTHIVMTDGVLSLEPLKFGVAGGSLATTAHLDGSAAPLKGRFSVAARHLKLKQLFPTQKVMQSALGEINGDAALSATGNSPAALAATSNGEVKMLMTDGAISRLLMEAAGLNVANVLYEKMFGSHDVKINCAAVDFVATNGLLDTKLFAFDTDDALINIDGPIDLRNESMNLKVHPHTKGFRVFSLRSPLYVKGTFKNPDVGVDAAALALRAGAMVGLGLVNPFAALIPLIAPSNNRDVPCSELFAQLKAPQKAANARK
>NZ_CP008777.1|WP_004534623.1|2300037_2300418_+|hypothetical-protein
MIRGLRRRAGPPPGRESGPIVADDDVGRLPARPVIAPANVVSTAAASERAARRPDPPGRGWAGRHRTNPTAAHARHAAERHAQAAHATADRFGAISSFPLSAGKERMARAFSGPEAHAAQRFIDSC
>NZ_CP008777.1|WP_004538238.1|2300461_2302054_+|ABC-F-family-ATPase
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVALEPNVRLGKLRQDQFAYEDVRVLDVVMMGHTEMWAAMTERDAIYANPEATDDDYMHAAELEAKFAEYGGYDAEARAGALLLGIGIEEKFHSGPMRDVAPGWKLRVLLAQALFSNPDVLLLDEPTNNLDINSIRWLEDTLNNYDSTMIIISHDRHFLNSVCTHMADMDYGTLKVWPGNYDDYMLASAQARERQAAANARAKERVAELQDFVRRFSANKSKARQATSRAKQIDKIKIEEFKPSSRQNPFIRFEFEKKLHNIAVVADSITKKYERTIFENFNLSVQPGERIAIIGENGAGKTTLLRALFGNLTLDHGTVKWAENANVGYMPQDTYEEFPNDVTLMDWIDQYRKDGDDETMVRGTLGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLLMDEPTNHMDMESIESLQIALEKFEGTLIFVSHDREFVSGLANRIIEVTTEGKLVDFGGNYEDFLASKGLQ
>NZ_CP008777.1|WP_004531382.1|2302200_2302836_-|eIF4A-inactivating-lethal-factor-BLF1
MPNSLEAQIRQAMKTGSTLTIEFDQALNQKSPGTLNVFLHPANGGVRIDLDSGNQGEPAKILWLPWKQGELQTLQPGSISTVDMLFFTYYLSGCKVFAGDGGPVWHIDAPVEANQFWRRMSSDEWMEDWEVGTDRQVAYLHRAGQSDSLWNLSAYLEGAAPSTYGRDNLGQAVVGGIVTGRQQMSLYQYATTSSGSSAWSPLTYTLQQRKQ
>NZ_CP008777.1|WP_004527142.1|2303151_2304588_+|aldehyde-dehydrogenase-family-protein
MKTCEQFYIGGAWRPSTGKGMIDVIDSGTEAVIGRVPEGTAEDAKAAVAAARAAFDGWAATPPAERARYLHKITENLKARSEELAQSITGEVGMPIKLSRAIQVGGPIYNWGAYAKLAETFAFEEQVGNSLVVREPVGVVAAITPWNYPLNQITLKVAAALAAGCTVALKPSEVAPLNAFILAEAIHDAGLPAGVFNLVCGYGPVVGEALASDADVDMVSFTGSTRAGKRVAELAAAGVKRVALELGGKSASVILDDADFAAAVKGTVSACYLNAGQTCSAHTRMLVPESRYEEARDLAKAAAQAYVAGDPRDDATRLGALASSVQQKRVQDYIRRGIDEGAELVTGGLGMPEGITRGFFVKPTVFGRVKPDATIAQEEIFGPVLSILTYRDEDDAVRIANDSPYGLGGAVWAGSDERAMRVARRIRTGQVDINGGAWNMAAPFGGFKQSGIGRENGVYGLDEYLEYKSMQLRPHKRA
>NZ_CP008777.1|WP_004191593.1|2304786_2305977_+|nitronate-monooxygenase
MTGSIPFPPLMIRGRSLLPIVQGGMGVGISAHRLAGSVAREGALGTIASIDLRHHHTDLIERCKRHPDRETMEAANLEALAREIQRAKTWGEGRGMIAVNVMKAVRSHADYVRIACEFGADAIVMGAGLPLDLPDMTQGHDIALIPILSDSRGIALVLKKWMKKGRLPDAIVIEHPARAGGHLGVTSLDDMDDPRFEFARVIDETRQTFATLGLERERIALVVAGGINSHEAVRAALAEGANGVQVGTPFAVTEEGDAHPNFKRVLANAKPDDIVEFLSVTGLPARAVKTPWLERYLRHETRIRAKIGALKQRCPSALECLSVCGLRDGIERFGHFCIDTRLAAALRGDVANGLFFRGREALPFGQAIRSVRDLLELLLTGTAPEAAANRPTFSLS
>NZ_CP008777.1|WP_004550362.1|2306049_2306694_+|OmpW-family-protein
MRRQTIRTCTTAIACAAGLAMIPSLSHAASPGEGINQGDIIARVRGISIMPDERTSNTLSALNVGVNNAIVPELDFTYMIRDYLGVELILGTSRHQITSSLGDLGGVGVLPPTLLLQYHFNHAGKVRPYVGAGINYTLFYNNGLHAGGEGIGINNHSFGPALQFGVDVQVTKKVFVNVDVKKIWMHTDATLGGQPLGRLNIDPLVVGVGVGMKF
>NZ_CP008777.1|WP_004191494.1|2306819_2307023_-|DUF1289-domain-containing-protein
MTSNLHDKPDSPCIGVCSTLFDEVCKGCGRTALEVANWVFMTDAEKQAVWERITREGTAMRFQYDKL

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP008777_1	1.3\|3798\|24\|NZ_CP008777\|CRISPRCasFinder	3798-3821	24	NZ_CP008777.1	3833-3856	0	1.0
NZ_CP008777_1	1.3\|3798\|24\|NZ_CP008777\|CRISPRCasFinder	3798-3821	24	NZ_CP008777.1	3840-3863	0	1.0
NZ_CP008777_1	1.3\|3798\|24\|NZ_CP008777\|CRISPRCasFinder	3798-3821	24	NZ_CP008777.1	3847-3870	0	1.0
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP008777.1	3891540-3891566	0	1.0
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP008777.1	2295712-2295738	0	1.0
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP008777.1	2295719-2295745	1	0.963
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP008777.1	3627678-3627704	2	0.926
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP008777.1	2295726-2295752	2	0.926
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP008778.1	1367233-1367259	0	1.0
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP008778.1	1367240-1367266	0	1.0
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP008778.1	1367247-1367273	1	0.963
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP008778.1	1367212-1367238	2	0.926
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP008778.1	1367254-1367280	2	0.926

1. spacer 1.3|3798|24|NZ_CP008777|CRISPRCasFinder matches to position: 3833-3856, mismatch: 0, identity: 1.0

ctcgcgtctcgcgtctcgcgtctc	CRISPR spacer
ctcgcgtctcgcgtctcgcgtctc	Protospacer
************************

2. spacer 1.3|3798|24|NZ_CP008777|CRISPRCasFinder matches to position: 3840-3863, mismatch: 0, identity: 1.0

ctcgcgtctcgcgtctcgcgtctc	CRISPR spacer
ctcgcgtctcgcgtctcgcgtctc	Protospacer
************************

3. spacer 1.3|3798|24|NZ_CP008777|CRISPRCasFinder matches to position: 3847-3870, mismatch: 0, identity: 1.0

ctcgcgtctcgcgtctcgcgtctc	CRISPR spacer
ctcgcgtctcgcgtctcgcgtctc	Protospacer
************************

4. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to position: 3891540-3891566, mismatch: 0, identity: 1.0

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccgcaaaccgcaaaccgcaaac	Protospacer
***************************

5. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to position: 2295712-2295738, mismatch: 0, identity: 1.0

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccgcaaaccgcaaaccgcaaac	Protospacer
***************************

6. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to position: 2295719-2295745, mismatch: 1, identity: 0.963

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccgcaaaccgcaaaccccaaac	Protospacer
********************* *****

7. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to position: 3627678-3627704, mismatch: 2, identity: 0.926

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccgcaaaccccaaaccccaaac	Protospacer
************** ****** *****

8. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to position: 2295726-2295752, mismatch: 2, identity: 0.926

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccgcaaaccccaaaccccaaac	Protospacer
************** ****** *****

9. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to position: 1367233-1367259, mismatch: 0, identity: 1.0

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccgcaaaccgcaaaccgcaaac	Protospacer
***************************

10. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to position: 1367240-1367266, mismatch: 0, identity: 1.0

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccgcaaaccgcaaaccgcaaac	Protospacer
***************************

11. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to position: 1367247-1367273, mismatch: 1, identity: 0.963

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccgcaaaccgcaaaccgcgaac	Protospacer
***********************.***

12. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to position: 1367212-1367238, mismatch: 2, identity: 0.926

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccacaaaccacaaaccgcaaac	Protospacer
*******.******.************

13. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to position: 1367254-1367280, mismatch: 2, identity: 0.926

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccgcaaaccgcgaaccgcgaac	Protospacer
****************.******.***

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP008777_1	1.2\|3742\|24\|NZ_CP008777\|CRISPRCasFinder	3742-3765	24	NZ_CP016173	Bordetella flabilis strain AU10664 plasmid unnamed1, complete sequence	2570-2593	3	0.875
NZ_CP008777_1	1.2\|3742\|24\|NZ_CP008777\|CRISPRCasFinder	3742-3765	24	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	624051-624074	3	0.875
NZ_CP008777_1	1.2\|3742\|24\|NZ_CP008777\|CRISPRCasFinder	3742-3765	24	NC_008193	Pasteurella phage F108, complete genome	16439-16462	3	0.875
NZ_CP008777_1	1.2\|3742\|24\|NZ_CP008777\|CRISPRCasFinder	3742-3765	24	DQ114220	Bacteriophage F108, complete genome	16439-16462	3	0.875
NZ_CP008777_1	1.2\|3742\|24\|NZ_CP008777\|CRISPRCasFinder	3742-3765	24	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	424565-424588	3	0.875
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	358731-358757	6	0.778
NZ_CP008777_3	3.2\|2295670\|27\|NZ_CP008777\|CRISPRCasFinder	2295670-2295696	27	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	358724-358750	8	0.704

1. spacer 1.2|3742|24|NZ_CP008777|CRISPRCasFinder matches to NZ_CP016173 (Bordetella flabilis strain AU10664 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.875

tctgcgctctgcgctctgcgtttt	CRISPR spacer
tctgcgctctgcgctctgcgatgc	Protospacer
******************** * .

2. spacer 1.2|3742|24|NZ_CP008777|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 3, identity: 0.875

tctgcgctctgcgctctgcgtttt	CRISPR spacer
actgtgctcggcgctctgcgtttt	Protospacer
 ***.**** **************

3. spacer 1.2|3742|24|NZ_CP008777|CRISPRCasFinder matches to NC_008193 (Pasteurella phage F108, complete genome) position: , mismatch: 3, identity: 0.875

tctgcgctctgcgctctgcgtttt	CRISPR spacer
tctgcgatctgcgctgtgcgtttc	Protospacer
****** ******** *******.

4. spacer 1.2|3742|24|NZ_CP008777|CRISPRCasFinder matches to DQ114220 (Bacteriophage F108, complete genome) position: , mismatch: 3, identity: 0.875

tctgcgctctgcgctctgcgtttt	CRISPR spacer
tctgcgatctgcgctgtgcgtttc	Protospacer
****** ******** *******.

5. spacer 1.2|3742|24|NZ_CP008777|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 3, identity: 0.875

tctgcgctctgcgctctgcgtttt	CRISPR spacer
actgtgctcggcgctctgcgtttt	Protospacer
 ***.**** **************

6. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.778

gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
gcaaaccgcaaaccgcaagccgttcgg	Protospacer
******************.***.  .

7. spacer 3.2|2295670|27|NZ_CP008777|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 8, identity: 0.704

-------gcaaaccgcaaaccgcaaaccgcaaac	CRISPR spacer
tccctgcgcaaaccgcaaaccgcaagc-------	Protospacer
       ******************.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

180768 : 209412

Burkholderia_virus(25.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004525957.1\|180768_181278_+\|transposase	transposase	NA	NA	NA	NA
WP_004556679.1\|181315_181417_+	hypothetical protein	NA	NA	NA	NA
WP_038723871.1\|182189_182531_+	hypothetical protein	NA	NA	NA	NA
WP_038723678.1\|182649_182874_+	hypothetical protein	NA	NA	NA	NA
WP_004543934.1\|183530_184079_+	hypothetical protein	A4JWV5	Burkholderia_virus	9.3e-75	78.7
WP_004543898.1\|184075_184837_+	nuclease	A4JWV4	Burkholderia_virus	2.1e-56	54.1
WP_004543876.1\|184842_185952_+	DUF3396 domain-containing protein	A4JWV3	Burkholderia_virus	1.2e-124	58.0
WP_038730680.1\|186389_187625_-	hypothetical protein	NA	NA	NA	NA
WP_111994465.1\|188517_188790_+\|transposase	transposase	NA	NA	NA	NA
WP_004543854.1\|189541_191104_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.2e-145	52.5
WP_004543818.1\|191133_191481_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	1.6e-40	72.9
WP_144399337.1\|191859_192618_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.8e-50	49.5
WP_004546200.1\|193517_194774_+\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	3.8e-47	33.0
WP_004545554.1\|194770_195637_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.6e-49	44.5
WP_052107457.1\|195663_196542_-	hypothetical protein	NA	NA	NA	NA
WP_100086167.1\|196544_198380_-	AAA domain-containing protein	K4I1H4	Acidithiobacillus_phage	5.8e-28	33.8
WP_004545947.1\|198450_199179_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_004545946.1\|199175_202262_-	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	3.9e-53	27.4
WP_144399338.1\|202271_203531_-	hypothetical protein	NA	NA	NA	NA
WP_038731785.1\|203521_205924_-	N-6 DNA methylase	A0A2H4PQP4	Staphylococcus_phage	2.1e-70	37.0
WP_004545941.1\|205995_206247_+	hypothetical protein	NA	NA	NA	NA
WP_004545945.1\|206910_207105_-	hypothetical protein	NA	NA	NA	NA
WP_004545935.1\|207305_208094_-	hypothetical protein	NA	NA	NA	NA
WP_085962187.1\|208178_209412_+\|transposase	IS3-like element ISButh1 family transposase	A0A1B0Z042	Pseudomonas_phage	3.1e-102	65.2

DBSCAN-SWA_2

862172 : 890650

Burkholderia_phage(44.44%)

protease,plate,tail,integrase

attL 862745:862783|attR 878223:878261

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004527881.1\|862172_862694_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.9e-21	51.0
862745:862783	attL	NA	NA	NA	NA
WP_004542707.1\|862887_863934_+\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	3.9e-53	38.7
WP_004542657.1\|865696_865951_+	hypothetical protein	NA	NA	NA	NA
WP_004542680.1\|865964_866615_+	hypothetical protein	NA	NA	NA	NA
WP_020850759.1\|866626_867019_+	hypothetical protein	NA	NA	NA	NA
WP_004542725.1\|867011_867860_+	type IV secretion system protein	NA	NA	NA	NA
WP_143291333.1\|867919_868171_+	hypothetical protein	NA	NA	NA	NA
WP_004542660.1\|868323_868605_+	hypothetical protein	NA	NA	NA	NA
WP_004542720.1\|869023_871999_+	conjugative relaxase	V5UQN3	Mycobacterium_phage	4.5e-06	28.8
WP_020850657.1\|872024_872276_-	hypothetical protein	NA	NA	NA	NA
WP_076847806.1\|872750_873197_+	hypothetical protein	NA	NA	NA	NA
WP_004542662.1\|873193_873463_+	hypothetical protein	NA	NA	NA	NA
WP_144399340.1\|873479_874139_+	hypothetical protein	NA	NA	NA	NA
WP_004545614.1\|874251_875166_-	three-Cys-motif partner protein TcmP	NA	NA	NA	NA
WP_076847687.1\|875177_876020_-	phage Gp37/Gp68 family protein	Q8W6R4	Burkholderia_virus	2.9e-67	43.3
WP_076847807.1\|876315_876954_+	DUF4433 domain-containing protein	NA	NA	NA	NA
WP_020850538.1\|876968_878030_+	macro domain-containing protein	B3FJ30	Pseudomonas_phage	3.1e-18	36.5
WP_004545634.1\|878870_879197_+	hypothetical protein	K4NZR5	Burkholderia_phage	4.3e-51	97.2
878223:878261	attR	NA	NA	NA	NA
WP_004527843.1\|879189_879603_+\|tail	phage tail protein I	K4NXA0	Burkholderia_phage	8.0e-71	100.0
WP_076852297.1\|879500_880103_+	site-specific DNA-methyltransferase	K4NZW3	Burkholderia_phage	4.3e-81	89.1
WP_111952238.1\|880496_881087_+	hypothetical protein	NA	NA	NA	NA
WP_004527840.1\|881190_881556_-	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	2.5e-52	88.4
WP_004521948.1\|881657_882443_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004521949.1\|882439_883786_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004521950.1\|883894_884509_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004531875.1\|884882_885554_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004521952.1\|885590_886109_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004521953.1\|886125_887616_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004527837.1\|887688_888192_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004204912.1\|888249_888732_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004527836.1\|888811_890650_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_3

1216327 : 1229644

Hokovirus(12.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004194034.1\|1216327_1218280_+	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2
WP_004522147.1\|1218548_1219679_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.7e-22	27.6
WP_004544052.1\|1219712_1221719_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	1.3e-52	35.0
WP_004194137.1\|1221902_1222718_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004532195.1\|1222782_1223466_-	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.0e-05	26.0
WP_004194373.1\|1223462_1223990_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004522151.1\|1224026_1225574_-	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2
WP_004194213.1\|1225570_1226257_-	HAD-IB family hydrolase	NA	NA	NA	NA
WP_004196484.1\|1226278_1227004_-	DnaA regulatory inactivator Hda	NA	NA	NA	NA
WP_004527676.1\|1227302_1228358_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SEW4	Cyanophage	6.4e-72	44.4
WP_004531014.1\|1228423_1229644_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	1.1e-240	100.0

DBSCAN-SWA_4

1592541 : 1601390

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004527508.1\|1592541_1593942_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.1e-79	38.5
WP_009921652.1\|1593973_1594897_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.3e-15	27.1
WP_004544120.1\|1594955_1595948_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_004189725.1\|1596019_1596337_+	competence protein ComE	NA	NA	NA	NA
WP_004532363.1\|1596678_1597581_+	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	1.9e-53	39.9
WP_004544022.1\|1597807_1599103_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004544116.1\|1599281_1600205_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	3.2e-43	35.9
WP_004544106.1\|1600547_1601390_-	alpha/beta hydrolase	A7XCB7	Tanapox_virus	1.2e-17	27.0

DBSCAN-SWA_5

2119500 : 2123984

Burkholderia_virus(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004196630.1\|2119500_2119764_+	hypothetical protein	Q8W6S4	Burkholderia_virus	2.2e-26	85.5
WP_071897863.1\|2119747_2119933_+	hypothetical protein	Q8W6S4	Burkholderia_virus	4.4e-21	85.2
WP_004534826.1\|2119953_2120679_-	hypothetical protein	A4PE26	Ralstonia_virus	1.7e-31	43.5
WP_038763587.1\|2120685_2121288_-	hypothetical protein	NA	NA	NA	NA
WP_004521248.1\|2121629_2122136_-	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	6.7e-19	39.4
WP_004521249.1\|2122132_2122558_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	1.1e-14	47.0
WP_004557051.1\|2122838_2123234_-	hypothetical protein	NA	NA	NA	NA
WP_004531416.1\|2123487_2123715_+	hypothetical protein	Q8W6S4	Burkholderia_virus	3.8e-22	75.8
WP_011851785.1\|2123750_2123984_-	hypothetical protein	A4PE26	Ralstonia_virus	2.1e-12	59.1

DBSCAN-SWA_6

2422862 : 2464448

Enterobacteria_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|2422862_2423983_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_050808995.1\|2424587_2425043_+	H-NS histone family protein	NA	NA	NA	NA
WP_004556997.1\|2425597_2426431_+	OmpA family protein	NA	NA	NA	NA
WP_004544416.1\|2426613_2428359_+	TolC family protein	NA	NA	NA	NA
WP_004544388.1\|2428544_2438159_+	hemolysin	NA	NA	NA	NA
WP_004531323.1\|2438305_2438764_+	hypothetical protein	NA	NA	NA	NA
WP_004521465.1\|2438760_2439636_+	sulfotransferase	NA	NA	NA	NA
WP_004544341.1\|2439670_2441962_+	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	1.6e-19	28.9
WP_004521467.1\|2441958_2443368_+	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
WP_004527044.1\|2443487_2447843_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_038730896.1\|2447884_2449510_+	hypothetical protein	NA	NA	NA	NA
WP_004527043.1\|2449787_2450393_+	adenylyl-sulfate kinase	A0A1B0XTK9	Freshwater_phage	4.1e-07	36.0
WP_004534880.1\|2451406_2452120_+	response regulator transcription factor	NA	NA	NA	NA
WP_085952178.1\|2453158_2454269_+\|transposase	IS3-like element ISBp1 family transposase	NA	NA	NA	NA
WP_004544383.1\|2454847_2454997_+	hypothetical protein	NA	NA	NA	NA
WP_004546200.1\|2455105_2456362_+\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	3.8e-47	33.0
WP_004545554.1\|2456358_2457225_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.6e-49	44.5
WP_085962191.1\|2458105_2459304_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.3e-49	39.6
WP_004544407.1\|2459882_2460176_+\|transposase	transposase	A0A1P8CWQ3	Bacillus_phage	1.4e-05	41.8
WP_144399342.1\|2460748_2461030_-	hypothetical protein	NA	NA	NA	NA
WP_038730902.1\|2461502_2461742_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_038730957.1\|2461750_2462329_-	DUF2975 domain-containing protein	NA	NA	NA	NA
WP_085962191.1\|2463249_2464448_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.3e-49	39.6

DBSCAN-SWA_7

2467781 : 2510417

Burkholderia_virus(25.0%)

transposase,integrase

attL 2487428:2487446|attR 2511135:2511153

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004544382.1\|2467781_2468912_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_050809000.1\|2470085_2471171_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_004544308.1\|2471200_2472184_+	hypothetical protein	NA	NA	NA	NA
WP_080011410.1\|2474461_2474680_-	hypothetical protein	NA	NA	NA	NA
WP_144399344.1\|2474815_2476138_-	hypothetical protein	NA	NA	NA	NA
WP_004544423.1\|2476265_2477213_-	ATP-binding protein	NA	NA	NA	NA
WP_004544466.1\|2477215_2479159_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_004544333.1\|2479155_2479815_-	hypothetical protein	NA	NA	NA	NA
WP_085952178.1\|2480636_2481748_-\|transposase	IS3-like element ISBp1 family transposase	NA	NA	NA	NA
WP_004534625.1\|2482005_2483256_+	DUF3443 family protein	NA	NA	NA	NA
WP_004544504.1\|2484259_2485360_-	porin	NA	NA	NA	NA
WP_080292750.1\|2485650_2486112_-\|transposase	transposase	NA	NA	NA	NA
WP_004531312.1\|2486225_2487860_-	aromatic amino acid lyase	NA	NA	NA	NA
2487428:2487446	attL	NA	NA	NA	NA
WP_004521480.1\|2487877_2489200_-	MFS transporter	Q6JIH2	Burkholderia_virus	9.1e-84	42.2
WP_004521481.1\|2489236_2490877_-	urocanate hydratase	NA	NA	NA	NA
WP_004544364.1\|2490895_2491987_-	DUF917 domain-containing protein	NA	NA	NA	NA
WP_004521483.1\|2492167_2493058_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004544395.1\|2493157_2494543_+	amidohydrolase family protein	NA	NA	NA	NA
WP_004521485.1\|2494539_2495820_+	Zn-dependent hydrolase	NA	NA	NA	NA
WP_004544441.1\|2495872_2496196_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_004527029.1\|2497575_2498121_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_004527028.1\|2498117_2498759_+	DUF1109 domain-containing protein	NA	NA	NA	NA
WP_009973415.1\|2498777_2499419_-	DUF1109 domain-containing protein	NA	NA	NA	NA
WP_004544348.1\|2499484_2499988_-	DoxX family protein	NA	NA	NA	NA
WP_004521491.1\|2499993_2500773_-	DUF2063 domain-containing protein	NA	NA	NA	NA
WP_004534478.1\|2500762_2501674_-	DUF692 domain-containing protein	NA	NA	NA	NA
WP_004521493.1\|2501707_2502019_-	DUF2282 domain-containing protein	NA	NA	NA	NA
WP_004521494.1\|2502586_2502967_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.4e-15	42.9
WP_004556978.1\|2503155_2503566_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_085955809.1\|2503655_2504790_+\|transposase	IS3 family transposase	Q716C2	Shigella_phage	6.5e-22	31.4
WP_004521496.1\|2505064_2505733_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_085962187.1\|2508083_2509317_+\|transposase	IS3-like element ISButh1 family transposase	A0A1B0Z042	Pseudomonas_phage	3.1e-102	65.2
WP_004544380.1\|2510018_2510417_-\|integrase	site-specific integrase	NA	NA	NA	NA
2511135:2511153	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2926668 : 2975925

Klosneuvirus(16.67%)

coat,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004204967.1\|2926668_2929293_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	5.5e-80	39.2
WP_004531186.1\|2929834_2931055_+	CoA transferase	NA	NA	NA	NA
WP_004534928.1\|2931394_2931604_-	hypothetical protein	NA	NA	NA	NA
WP_004545247.1\|2931883_2933593_+\|tRNA	glutamine--tRNA ligase/YqeY domain fusion protein	A0A222YZ70	Escherichia_phage	7.4e-187	57.3
WP_004545254.1\|2933924_2934407_-	NUDIX hydrolase	A0A0G2SS60	Proteus_phage	1.5e-20	42.0
WP_004545113.1\|2934425_2934812_-	hypothetical protein	NA	NA	NA	NA
WP_004545161.1\|2935099_2937199_-	glycoside hydrolase family 3 protein	NA	NA	NA	NA
WP_004521727.1\|2937124_2937304_+	hypothetical protein	NA	NA	NA	NA
WP_004545120.1\|2937300_2938161_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_004545219.1\|2938196_2939603_-	cytochrome-c peroxidase	NA	NA	NA	NA
WP_004193177.1\|2939836_2941420_+	acid phosphatase	NA	NA	NA	NA
WP_045591085.1\|2941531_2942995_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	1.2e-79	38.3
WP_004538373.1\|2943203_2944397_+	trans-2-enoyl-CoA reductase family protein	NA	NA	NA	NA
WP_004531180.1\|2945020_2946208_+	HlyD family secretion protein	NA	NA	NA	NA
WP_004545235.1\|2946380_2948000_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004545213.1\|2948001_2949693_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004192810.1\|2949996_2950629_-	response regulator transcription factor	NA	NA	NA	NA
WP_004545138.1\|2950629_2952711_-	response regulator	A0A1V0SGR3	Hokovirus	3.9e-12	26.3
WP_004196717.1\|2953121_2954087_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004545118.1\|2954102_2956514_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_004526784.1\|2956558_2957398_-	molecular chaperone	NA	NA	NA	NA
WP_004526783.1\|2957415_2957940_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526782.1\|2958016_2958577_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004538378.1\|2958629_2959175_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004534686.1\|2959161_2959350_-	hypothetical protein	NA	NA	NA	NA
WP_004531175.1\|2959435_2959657_-	hypothetical protein	NA	NA	NA	NA
WP_004196705.1\|2959994_2960888_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004538381.1\|2961304_2962591_+	MFS transporter	NA	NA	NA	NA
WP_004526776.1\|2962635_2963619_+	amidohydrolase family protein	NA	NA	NA	NA
WP_004193855.1\|2964086_2964368_+	H-NS histone family protein	NA	NA	NA	NA
WP_004191144.1\|2964630_2964900_-	hypothetical protein	NA	NA	NA	NA
WP_004526773.1\|2965794_2967108_-	divalent metal cation transporter	NA	NA	NA	NA
WP_038731356.1\|2967367_2968288_-	hypothetical protein	NA	NA	NA	NA
WP_153260188.1\|2968945_2969371_-	hypothetical protein	NA	NA	NA	NA
WP_052139777.1\|2970514_2970961_-	hypothetical protein	NA	NA	NA	NA
WP_038723406.1\|2971242_2971503_-	hypothetical protein	NA	NA	NA	NA
WP_009951519.1\|2971717_2971885_+	hypothetical protein	A0A0P0ZBS5	Stx2-converting_phage	9.5e-07	50.0
WP_076851597.1\|2972457_2973171_-	hypothetical protein	NA	NA	NA	NA
WP_076851599.1\|2974093_2974387_-	hypothetical protein	NA	NA	NA	NA
WP_111963064.1\|2975016_2975925_-\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

3600339 : 3611297

Agrobacterium_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004196461.1\|3600339_3602640_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.1e-167	42.1
WP_004194131.1\|3602636_3602951_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6
WP_004196460.1\|3603483_3603687_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004543858.1\|3603816_3605427_-	multicopper oxidase family protein	NA	NA	NA	NA
WP_004189626.1\|3605439_3605622_+	hypothetical protein	NA	NA	NA	NA
WP_004189552.1\|3605594_3606854_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_004189780.1\|3607121_3607700_+	pseudouridine synthase	NA	NA	NA	NA
WP_071810810.1\|3607962_3608181_+	hypothetical protein	NA	NA	NA	NA
WP_004530837.1\|3608372_3608882_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.5e-13	41.2
WP_004197486.1\|3609182_3611297_+	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP008778

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP008778_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008778_1

1032039-1032131

Orphan

Consensus_repeat	Method
TCGCCGCCGCGCGCGACGACGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP008778_1

>merge|NZ_CP008778|1|1032039-1032131|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGCTGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGATCGCCGCCGCGCGCGCCGACGCGC

>NZ_CP008778|1|1|1032039-1032131|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGC	TGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGA
TCGCCGCCGCGCGCGCCGACGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008778.1\|WP_004544786.1\|1032566_1034567_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183987
NZ_CP008778.1\|WP_004549747.1\|1030568_1030877_+\|membrane-protein	unknown	unknown	gnl\|CDD\|274462
NZ_CP008778.1\|WP_004524980.1\|1024455_1025859_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236180
NZ_CP008778.1\|WP_004544538.1\|1040230_1042066_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_CP008778.1\|WP_004524979.1\|1023280_1024459_-\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|235922
NZ_CP008778.1\|WP_004544573.1\|1042215_1043340_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223912
NZ_CP008778.1\|WP_004188221.1\|1029629_1030085_+\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|184057
NZ_CP008778.1\|WP_004524989.1\|1037289_1037799_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008778.1\|WP_004524995.1\|1046584_1047658_-\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|235136
NZ_CP008778.1\|WP_004187193.1\|1031571_1031820_+\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|184067
NZ_CP008778.1\|WP_004187346.1\|1030873_1031575_+\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|237383
NZ_CP008778.1\|WP_041286540.1\|1030081_1030576_+\|AtpZ/AtpI-family-protein	unknown	unknown	gnl\|CDD\|378198
NZ_CP008778.1\|WP_004188840.1\|1025869_1027663_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|213656
NZ_CP008778.1\|WP_004544729.1\|1034563_1035412_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|376304
NZ_CP008778.1\|WP_004544624.1\|1043342_1046588_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP008778.1\|WP_004198322.1\|1036728_1037232_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008778.1\|WP_004544533.1\|1028023_1029640_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|183615
NZ_CP008778.1\|WP_004529178.1\|1035626_1036652_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|176257
NZ_CP008778.1\|WP_004544788.1\|1027794_1028052_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008778.1\|WP_004544764.1\|1038339_1039905_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|185008

Protein	Function_ID	Function_description	E-value
NZ_CP008778.1\|WP_004544786.1\|1032566_1034567_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|183987	PRK13343, PRK13343, F0F1 ATP synthase subunit alpha; Provisional.	0
NZ_CP008778.1\|WP_004549747.1\|1030568_1030877_+\|membrane-protein	gnl\|CDD\|274462	TIGR03165, F1F0_chp_2, F1/F0 ATPase, Methanosarcina type, subunit 2. Members of this protein family are uncharacterized, highly hydrophobic proteins encoded in the middle of apparent F1/F0 ATPase operons. We note, however, that this protein is both broadly and sparsely distributed. It is found in about only about two percent of microbial genomes sequenced, with the first ten examples found coming from the Euryarchaeota, Chlorobia, Betaproteobacteria, Deltaproteobacteria, and Planctomycetes. In most of these species, surrounding operon appears to represent a second F1/F0 ATPase system, and the member proteins belong to subfamilies with the same phylogenetic distribution as the current protein family.	3.91378e-10
NZ_CP008778.1\|WP_004524980.1\|1024455_1025859_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	gnl\|CDD\|236180	PRK08190, PRK08190, bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated.	0
NZ_CP008778.1\|WP_004524979.1\|1023280_1024459_-\|acetate/propionate-family-kinase	gnl\|CDD\|235922	PRK07058, PRK07058, acetate/propionate family kinase.	0
NZ_CP008778.1\|WP_004544573.1\|1042215_1043340_-\|ABC-transporter-permease	gnl\|CDD\|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	1.21198e-25
NZ_CP008778.1\|WP_004188221.1\|1029629_1030085_+\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|184057	PRK13447, PRK13447, F0F1 ATP synthase subunit epsilon; Provisional.	4.44077e-63
NZ_CP008778.1\|WP_004524995.1\|1046584_1047658_-\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|235136	PRK03598, PRK03598, putative efflux pump membrane fusion protein; Provisional.	1.83012e-39
NZ_CP008778.1\|WP_004187193.1\|1031571_1031820_+\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|184067	PRK13468, PRK13468, F0F1 ATP synthase subunit C; Provisional.	4.45015e-37
NZ_CP008778.1\|WP_004544729.1\|1034563_1035412_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|376304	pfam00231, ATP-synt, ATP synthase.	7.12333e-32
NZ_CP008778.1\|WP_004187346.1\|1030873_1031575_+\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|237383	PRK13421, PRK13421, F0F1 ATP synthase subunit A; Provisional.	1.54059e-122
NZ_CP008778.1\|WP_004188840.1\|1025869_1027663_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.3979e-179
NZ_CP008778.1\|WP_004544538.1\|1040230_1042066_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	5.37185e-132
NZ_CP008778.1\|WP_004544624.1\|1043342_1046588_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.12967e-92
NZ_CP008778.1\|WP_004544533.1\|1028023_1029640_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|183615	PRK12597, PRK12597, F0F1 ATP synthase subunit beta; Provisional.	0
NZ_CP008778.1\|WP_004529178.1\|1035626_1036652_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP008778.1\|WP_041286540.1\|1030081_1030576_+\|AtpZ/AtpI-family-protein	gnl\|CDD\|378198	pfam09527, ATPase_gene1, Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter. This model represents a protein found encoded in F1F0-ATPase operons in several genomes, including Methanosarcina barkeri (archaeal) and Chlorobium tepidum (bacterial). It is a small protein (about 100 amino acids) with long hydrophobic stretches and is presumed to be a subunit of the enzyme. It carries two transmembrane helices and is a magnesium or calcium uniporter. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI.	6.31616e-17
NZ_CP008778.1\|WP_004544764.1\|1038339_1039905_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	2.54749e-79

>NZ_CP008778.1|WP_004187193.1|1031571_1031820_+|F0F1-ATP-synthase-subunit-C
MNNLIEVVSIAAAALAVSFGAIGPALAEGRAVGAAMDAIARQPDASGTVSRTLFVGLAMIETMAIYCLVVALLLLFANPFVK
>NZ_CP008778.1|WP_004187346.1|1030873_1031575_+|F0F1-ATP-synthase-subunit-A
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>NZ_CP008778.1|WP_004549747.1|1030568_1030877_+|membrane-protein
MIEMWETARASFDGIAAAIGLALGFAAGACHFVSLGWNSRLFVAGRAGVALALQLARVALAVAVLVVLARAGFGMLVAGSAGFFAARAIAVRRAAALTGARR
>NZ_CP008778.1|WP_041286540.1|1030081_1030576_+|AtpZ/AtpI-family-protein
MMKRRPPEVKREARDDAARGDARHAGAGAAPDDPRGAARRDPSPGSPRAARGGATHPAARAAEPAAPKPAADRVERAAHTAAARAARGARDPEPSLGRRLAQIGVLGWTIVAPTLAALALGRWLDRMFATRVFFSAPLLMLGAALGLWLAWRWMKAQQHGDRDD
>NZ_CP008778.1|WP_004188221.1|1029629_1030085_+|F0F1-ATP-synthase-subunit-epsilon
MGAELRVTIATPARVCVDDLPIVSLRAEDASGAFGIRAGHVDFVTLLRASVVRWRTADGATHYAALDGGVLRVTRGARIEIACRDAVLGESLAELEAVVRGVRATQLDEKRRARVDETRLHAQAVRRLLTYLRPEHAKDGVHAPLKPETLE
>NZ_CP008778.1|WP_004544533.1|1028023_1029640_+|F0F1-ATP-synthase-subunit-beta
MADPQATNGTGAVCAERDASDVGDVSDVGDARDEGAGRVVAVRGAVVDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPLLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVLVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASVAGPGTTSGTTSDPASGSAEPQGARHGR
>NZ_CP008778.1|WP_004544788.1|1027794_1028052_-|hypothetical-protein
MPFVACGSATFAPVWLVRRWLHHNGARRPPADLGQETGNRQTKRGIAQSETIDASASGADTVRAASIVDSNQIPQTYAWLQWPYQ
>NZ_CP008778.1|WP_004188840.1|1025869_1027663_-|alpha/beta-fold-hydrolase
MDTRHAPESGAPDAPLPAHPPASYAPESPYRIFDLAKEASVAKLTSGLSPASLQLALADWLIHLAAAPGKRAELATLALRHAALLGQYLLEAATGRTPAAPAQPSPGDRRFRAGAWQLEPYRFWHQSFLLAEQWWRAATRDVPGVSPHHEDVVAFSARQMLDTFAPANYVATNPEIAQRTALTGGANLAQGVWNYLDDVRRLITKQPPAGAEQFELGRNLATTPGRVVFRNHLIELLQYSPTTPDVYAQPVLIVPAWIMKYYILDLSAHNSLIRYLVGEGHTVFCISWRNVDASDRDLSLDDYRKLGVMDALDTIGAIVPGEKIHATGYCLGGTLLSIAAAAMANTGDDRLASITLLAAQTDFAEPGELQLFIDDSEIHFLESMMWERGYLGAHQMAGSFQLLMSNDLIWSRVIHDYLLGERTPMIDLMAWNADSTRMPYRMHSEYLRHLFLDNDLATNRYVIDGQTVSVHNIRAPFFVVGTEHDHIAPWRSVYKIHYLSGSDVTFVLTAGGHNAGIVSEPGHAKRHYRMKMTAAAAPSISPDEWLAGATDFEGSWWPAWHAWLARHSSPQRVAPPPLGKPGAHTLGDAPGTYVFQK
>NZ_CP008778.1|WP_004524980.1|1024455_1025859_-|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase
MDREILQNRPFDSLAIGDSASLVRTASRDDIDLFAAMSGDVNPAHLDAAFAAHDLFGHVVVHGMWTGALVSAVLGTKLPGPGTIYLDQTLEFRHPVAPGDTITATVTVAEKRPEKRIVLLDTRCTNQDGHVVLRGTATVIAPDTPITWERVPGPEVAVRRHDRYETFVRDAREQPPLRTAIVHPCSPDALRAAIDARDANLIEPILIGPQAKIRAIADAAGVDLAGVPIEAVEHSHAAAARAVEMGGAGEVAALMKGSLHTDELLAAVIGPASRLRTERRISHVYAMDVPAYPKPLLITDAAINIAPTLEQKRDICQNAVDLLHVLGVERPRVAVLAAVETVNPKMPSTLDAAALTVMAARGQIAGAIVDGPLAFDNAVSAVAAMSKGIASPVAGDADVLLVPDLEAGNMLAKQLMYFAGADAAGLVLGARLPIILTSRADSLRVRIASAALAKLVAERTRAGALAS
>NZ_CP008778.1|WP_004524979.1|1023280_1024459_-|acetate/propionate-family-kinase
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHTVPLAAPVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHVRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATRCGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLGVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
>NZ_CP008778.1|WP_004544786.1|1032566_1034567_+|F0F1-ATP-synthase-subunit-alpha
MTPTPDAPAAADAATGAGWLARRRGALARVALAPVAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGALDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSPEASREVSREVSREASHEANRDAAADAARVAGRAPGRAEPDRAAPRAMPDGPPRAQADGDRASASRPPPDARGDAARTAPSPQGGAEVNVNAAANVDAEAEARHKR
>NZ_CP008778.1|WP_004544729.1|1034563_1035412_+|F0F1-ATP-synthase-subunit-gamma
MSDKLAAIEARTDTARQLQTVIGAMQGVAAARAHEAQQRLPGIRASAATVGAAIGDALSAGARSGDTAAGARAAPRARLVVVLCSEQGFIGAYNAQLIEHATRPGPSVSREYMMVGSRGAMLADAGGVPLVWRTPMAARADDVVHLANRITDALYAHLAKRGAQPVSIVHAMPGGAARLEVAERRLLPFDYARFDTAPRAQPPLVHLPPATLLAELAQAYVFVELCEAAMLAFAAENEARTRAMIAARESVERALGDLLQAYRIARQDEITADIVELAASGL
>NZ_CP008778.1|WP_004529178.1|1035626_1036652_+|alcohol-dehydrogenase-AdhP
MAQYMKAAVVHAFGEPLRIEEVPVPTPGAGQILVNVKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGFVAAVGEGVRHVKEGDRVGVPWLYTACGHCEYCQTGWETLCHEQQNTGYSVNGSYAEYVLADPNYVGHLPSNVAFDEIAPILCAGVTVYKGIRVTDTRPGQWIAISGIGGLGHVAVQYAKAMGLHVVAVDVAPQKLELARKLGAAFVVDASKDDPAAVIQKEIGGVHGVLVTAVSRGAFAQALGMVRRGGTVSLNGLPPGDFPLPIFSTVLNGITVRGSIVGTRRDLQESLDFAAEGLVRAHIHRDKLEHINGVFSALREGKVDGRIVLTGQ
>NZ_CP008778.1|WP_004198322.1|1036728_1037232_+|hypothetical-protein
MRGAGRASPSRARRYENVSKEPNTHREAGAPVHRYRLQVRNMNGECRTYELRLSSLDDGYTLEIDEWLNFPDTHLGDVTPVHVSRPVQFAVPAHEFYRRRRAFRTELIESVAAALRAGEVVRMRDSPDEYPGGHAGNPWVNWIRADLRANPGGRPPPVGDDMQDLIH
>NZ_CP008778.1|WP_004524989.1|1037289_1037799_-|hypothetical-protein
MRRIYFLLPDADTARAIVDELLLKRIEWRHIHVVANDRVPLENLPEASIAQSSDLLPALARGTAAGGVTGALAGLAAIAFPPAGLTIAGGAVVAFAIAGAGFGAWVGTMIGVSVPNTRLKHFEDAVDNGELLMMIDVHRDRVEEIEALVKQHHPNAHLEGTDPTIPAFP
>NZ_CP008778.1|WP_004544764.1|1038339_1039905_+|methyl-accepting-chemotaxis-protein
MPTLSFRQKLWLPLAISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPFATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALIGRAAERVGNGTELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDSVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>NZ_CP008778.1|WP_004544538.1|1040230_1042066_-|response-regulator
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTERVLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQMLSAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLEPRGLIDGMREMLHRALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVVDMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHARADPRAKTAAARVQR
>NZ_CP008778.1|WP_004544573.1|1042215_1043340_-|ABC-transporter-permease
MRRLAIVYRLGVKELWSLVRDPILLVLIAYTFTASIYSAATARPDTLHMAPIAIIDEDASPLSARIASAFFPPQFALPRMVTLAEADRGMNAGDFTFALDIPPNFQRDVLAGRPAQIQLNVDATRMSQAFTGNGYVQQIVSGEIDDFARRYRANTAPPVDIAMHMRFNPNLDQTWFGSLMEVINNVTLLSMVLTGAALIREREHGTIEHLLVMPVTPGEIMLAKVWSMGLVVACAAAFSLAFVVRGALHVPIEGSVALFVIGMAIHLFATTSMGIFLATLVRSMPQFGMLLVLVLLPLQLLSGSLTPRESMPFAVQNIMLAAPTTHFVEIGQAILYRGAGIETVWRQFLILAVIGTALFLLSLKRFRKTIGQMA
>NZ_CP008778.1|WP_004544624.1|1043342_1046588_-|ATP-binding-cassette-domain-containing-protein
MSAPSVVRFSDVSLRYGKTVALERITLEIPAGLTIGLIGPDGVGKSSLLALAAGARALQTGAVDALGGDMRSRRHRERVCRRIAYMPQGLGKNLYPTLSVEENLQFFARLFGHDADERRRRIDALTRSTGLFAFLSRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLARAQFWDLIARIRSERPAMSVIVATAYMDEAQRFDWLIAMDAGRVLATGAPAELLARTGCDSLEAAFIALLPEDERRGHKPVTLEPLRADAQTGTAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGTAQLFGKTVDPKDINTRRRVGYMSQAFSLYSELTVRQNLVLHARLFGVPAAEIDARVDEMARRFGLADIYDMLPDSLPLGMRQRLSLAVAMVHKPELLILDEPTSGVDPVARDSFWQLMIDLARRDRVTIFISTHFMNEAQRCDRISLMHAGRVLASDAPAALVRARGAATLEEAFIGYLVDASAQEAQEAQGGAGERPGAGERAAGESVAGRGAATDGDADGAHARPAAYANGAAQHRAPDADAAGTDVAAETGARDDARTAHAAGHSAGNDVRATVGSEVGSEVGSDVASEAGPEAGLAASAESGAERAREPAADITADAGAAIDVEPGASAESATAAVAPARHAESAATSPRAGNAPAGTPFAAAPPSHAAPAEPPHRAFSAQRALSYMWREMLELRRDPVRATLALIGSLVLMCVIGIGISLDVEDLTYAVLDRDQTELSHDYALNLSGSRYFVERPPIADYAALDRRMRDGELSLAIEIPPNFARDVERGAPAQIGMWIDGAMPQRAETIRGYAIGMHTMWLADKARHRLGVTLAPRAEVVTRYRYNPDVKSLPAMIPAVMPLLLLMLPAMLTALAVVRERELGSILNLYVTPVTRTEFLIGKQVPYVVLAMLNFLLMTMLARIAFDVPVKGSFMTLLLAVLIFNVVATGIGLLASTFTRSQVAAIVMTIIGTMIPTVQFAGLLTPLSSLEGTGRLIGLVYPATYMLSISRGVFNKALSLHDLYSQFWPLAACVPVILGATILLLKKQER
>NZ_CP008778.1|WP_004524995.1|1046584_1047658_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MIQVTRKQIVAAAAVVVVALGAYYGWTLLRHQGPGDGFASGNGRIEATEIDVATKLPGRIDAILVDEGDFVKAGQPLANMQIQVLRAQYDEATAQRQRALNTAAGVQSQVAQRKSDKAAAQAMVVLRESELDAAERRLARSQTLSREGASSLQELDDDRARARSAQAAVSAAAAQVAAAQAAIEATEAQLVAAHSAVTAADATVARVQADIDDSQLASPRDGRVQYRVAQPGEVLPAGGKVLNLVDLSDVYMTFFLPETVVGRVALGADARIILDAAPNYVIPATVSFVSSTAQFTPKTVETANERQKLMFRVKARIDRELLQKHLKLVKTGLPGVAWVRVDPSKPWPAQLMVKVPQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

799761 : 851790

Ralstonia_phage(25.0%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190585.1\|799761_801165_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004529328.1\|801180_802497_+	DotU family type VI secretion system protein	NA	NA	NA	NA
WP_004524806.1\|802499_806129_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_162478379.1\|806110_807067_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_004529325.1\|807051_807279_-	hypothetical protein	NA	NA	NA	NA
WP_004544825.1\|807277_809869_+	serine/threonine protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	5.0e-09	26.6
WP_004190988.1\|809921_811001_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004524810.1\|811063_811642_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190849.1\|811634_813143_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004190698.1\|813202_813694_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_009935240.1\|813712_814261_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004524812.1\|814265_816137_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_100086149.1\|816133_817591_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004533146.1\|817603_820270_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	5.2e-78	30.6
WP_038731030.1\|820266_822471_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	2.8e-45	29.7
WP_038731121.1\|822486_823197_+	hypothetical protein	NA	NA	NA	NA
WP_004544731.1\|823126_825139_+\|transposase	transposase	S5WIU1	Leptospira_phage	2.7e-31	50.4
WP_157801140.1\|826182_826434_+	hypothetical protein	NA	NA	NA	NA
WP_076838791.1\|826444_827596_-	hypothetical protein	NA	NA	NA	NA
WP_004544694.1\|831878_832280_+	VENN motif pre-toxin domain-containing protein	NA	NA	NA	NA
WP_071811399.1\|832283_832538_+	hypothetical protein	NA	NA	NA	NA
WP_076838784.1\|832539_833106_+	suppressor of fused domain protein	NA	NA	NA	NA
WP_162478380.1\|834920_835718_+	DUF746 domain-containing protein	NA	NA	NA	NA
WP_162478385.1\|835393_835900_-	recombinase family protein	A0JC18	Ralstonia_phage	3.3e-18	52.8
WP_009960547.1\|835865_836021_-	recombinase family protein	A0A0C4UR34	Shigella_phage	2.0e-06	67.6
WP_004524822.1\|836449_837190_-	hypothetical protein	NA	NA	NA	NA
WP_004536893.1\|838532_839687_+	LacI family transcriptional regulator	NA	NA	NA	NA
WP_004557920.1\|841459_842098_+	hypothetical protein	NA	NA	NA	NA
WP_004524825.1\|842140_843385_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	7.1e-22	32.8
WP_004524827.1\|843420_844662_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_004524828.1\|844724_845648_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_004524829.1\|845648_846500_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_004544761.1\|846504_848676_+	alpha-galactosidase	NA	NA	NA	NA
WP_004544789.1\|848916_850950_+	hypothetical protein	NA	NA	NA	NA
WP_004555373.1\|851382_851790_+\|transposase	transposase	A0A0P0ZCV4	Stx2-converting_phage	4.9e-12	36.5

DBSCAN-SWA_2

2915945 : 2983822

Aeromonas_phage(25.0%)

plate,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004530063.1\|2915945_2916896_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004523149.1\|2917163_2918108_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004530060.1\|2918579_2920283_+	thermolysin metallopeptidase	NA	NA	NA	NA
WP_004545903.1\|2920400_2921627_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_004200640.1\|2921681_2922824_-	porin	NA	NA	NA	NA
WP_004198249.1\|2922932_2923055_-	hypothetical protein	NA	NA	NA	NA
WP_004530058.1\|2923051_2924089_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004186939.1\|2924085_2925639_-\|holin	choline-sulfatase	NA	NA	NA	NA
WP_004554841.1\|2925801_2926674_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004186920.1\|2926817_2927693_+	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_004530057.1\|2927779_2929435_-	APC family permease	NA	NA	NA	NA
WP_004186918.1\|2929615_2930479_-	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004530056.1\|2930588_2931734_-	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004535147.1\|2931754_2932996_-	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004530055.1\|2933047_2933833_-	drug:proton antiporter	NA	NA	NA	NA
WP_004523138.1\|2933829_2935002_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_004538949.1\|2935006_2936932_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_004523137.1\|2936934_2938998_-	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_004186987.1\|2939058_2939592_-	4-vinyl reductase	NA	NA	NA	NA
WP_004186989.1\|2939742_2940714_-	membrane dipeptidase	NA	NA	NA	NA
WP_004545861.1\|2940786_2942061_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	5.3e-105	54.1
WP_009933096.1\|2942072_2942324_-	hypothetical protein	NA	NA	NA	NA
WP_004198247.1\|2942493_2943519_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004523135.1\|2943696_2944896_-	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	8.4e-12	27.2
WP_004530800.1\|2945489_2946506_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_004546670.1\|2946694_2948260_+	glycoside hydrolase 68 family protein	NA	NA	NA	NA
WP_004545881.1\|2948392_2950057_+	glycoside hydrolase family 32 protein	F8WPR5	Bacillus_phage	1.6e-56	31.4
WP_004528656.1\|2952548_2954132_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_076847054.1\|2954128_2954311_-	hypothetical protein	NA	NA	NA	NA
WP_009927659.1\|2954436_2955432_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_004542407.1\|2955683_2957267_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_038731734.1\|2957263_2958583_-	glycosyltransferase	NA	NA	NA	NA
WP_004547901.1\|2958472_2958775_+	hypothetical protein	NA	NA	NA	NA
WP_004524288.1\|2958816_2959716_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_004536812.1\|2960266_2960542_-	hypothetical protein	NA	NA	NA	NA
WP_004545583.1\|2960862_2961294_-	hypothetical protein	NA	NA	NA	NA
WP_004190863.1\|2961316_2961676_-	hypothetical protein	NA	NA	NA	NA
WP_004545523.1\|2961734_2965238_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004525553.1\|2965234_2966893_-	OmpA family protein	NA	NA	NA	NA
WP_004525552.1\|2966975_2968337_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004530042.1\|2968333_2968927_-	type VI secretion lipoprotein TssJ	NA	NA	NA	NA
WP_004190606.1\|2968932_2969322_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004530790.1\|2969364_2970081_-	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004525550.1\|2970083_2971154_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_038731551.1\|2971153_2973370_-	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_004545596.1\|2973373_2975662_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004545502.1\|2975827_2978119_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004545559.1\|2978109_2980971_-	type VI secretion system ATPase TssH	A0A2I7REQ1	Vibrio_phage	2.3e-60	27.2
WP_004190851.1\|2980973_2981963_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004545527.1\|2981959_2983822_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_3

3140529 : 3165249

Burkholderia_virus(46.15%)

transposase,integrase

attL 3124992:3125007|attR 3156986:3157001

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3124992:3125007	attL	NA	NA	NA	NA
WP_111963057.1\|3140529_3141225_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_009932882.1\|3141668_3142601_-	glycerophosphoryl diester phosphodiesterase	NA	NA	NA	NA
WP_100086160.1\|3142785_3144021_-	c-type cytochrome	NA	NA	NA	NA
WP_004545516.1\|3144179_3145640_-	ser/threonine protein phosphatase	NA	NA	NA	NA
WP_004525420.1\|3147650_3147935_-	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	1.4e-10	50.0
WP_004549731.1\|3147918_3148188_-	BrnT family toxin	NA	NA	NA	NA
WP_004537565.1\|3148757_3149033_+	bacteriophage protein Gp49	Q6JIH4	Burkholderia_virus	5.2e-42	95.6
WP_009923452.1\|3149042_3149174_+	bacteriophage protein Gp48	Q8W6Q2	Burkholderia_virus	2.6e-15	97.7
WP_004545584.1\|3149311_3149554_+	hypothetical protein	NA	NA	NA	NA
WP_004552392.1\|3149756_3149975_+	hypothetical protein	Q6JIH9	Burkholderia_virus	9.8e-36	98.6
WP_004545536.1\|3150160_3150814_-	hypothetical protein	Q8W6Q5	Burkholderia_virus	6.7e-112	99.5
WP_041286571.1\|3151099_3152320_+\|transposase	ISL3 family transposase	A9YX10	Burkholderia_phage	8.6e-238	99.3
WP_004537646.1\|3152377_3152527_+	bacteriophage protein Gp44	Q8W6Q6	Burkholderia_virus	3.3e-19	100.0
WP_004542585.1\|3152523_3153723_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A4JX31	Burkholderia_virus	1.1e-224	99.5
WP_004545504.1\|3154130_3155897_-	hypothetical protein	NA	NA	NA	NA
WP_085955809.1\|3156064_3157200_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	6.5e-22	31.4
3156986:3157001	attR	NA	NA	NA	NA
WP_038731574.1\|3157253_3157544_-	hypothetical protein	NA	NA	NA	NA
WP_004545553.1\|3157748_3158342_-	recombinase family protein	A0A219Y912	Aeromonas_phage	5.2e-23	38.6
WP_050809013.1\|3158537_3159062_-	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_004546200.1\|3159217_3160474_+\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	3.8e-47	33.0
WP_004545554.1\|3160470_3161337_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.6e-49	44.5
WP_144399358.1\|3161337_3161748_-	hypothetical protein	NA	NA	NA	NA
WP_038731576.1\|3161880_3162249_-	hypothetical protein	NA	NA	NA	NA
WP_144399359.1\|3162809_3163979_+	hypothetical protein	NA	NA	NA	NA
WP_085962187.1\|3164015_3165249_+\|transposase	IS3-like element ISButh1 family transposase	A0A1B0Z042	Pseudomonas_phage	3.1e-102	65.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP008777

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP008778

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection