CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP009896	Pimelobacter simplex strain VKM Ac-2033D chromosome, complete genome	17 crisprs	DinG,csa3,WYL,cas3,DEDDh,cas4	0	1	4	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP009896_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_1

363500-363609

Orphan

Consensus_repeat	Method
AGTTTCGCCGGTCGACCGGCGAAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_1

>merge|NZ_CP009896|1|363500-363609|CRISPRCasFinder
AGTTTCGCCGGTCGACCGGCGAAACTCACACTGGACCGATGAAGTTCCGTCGGTCAGGCGTGAGTTTTGTACGTCAAGTCCGACAGTTTCGCCGGTCGACCGGCGAAACT

>NZ_CP009896|1|1|363500-363609|CRISPRCasFinder
AGTTTCGCCGGTCGACCGGCGAAACT	CACACTGGACCGATGAAGTTCCGTCGGTCAGGCGTGAGTTTTGTACGTCAAGTCCGAC
AGTTTCGCCGGTCGACCGGCGAAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038676160.1\|351985_353341_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|185378
NZ_CP009896.1\|WP_052138122.1\|359600_360653_+\|DUF2510-domain-containing-protein	unknown	unknown	gnl\|CDD\|378480
NZ_CP009896.1\|WP_052138121.1\|355777_356575_+\|DUF2817-domain-containing-protein	unknown	unknown	gnl\|CDD\|349475
NZ_CP009896.1\|WP_038676171.1\|367363_368650_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP009896.1\|WP_038676175.1\|369557_370139_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038676181.1\|371161_371488_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP009896.1\|WP_038676173.1\|368775_369561_+\|TIGR04255-family-protein	unknown	unknown	gnl\|CDD\|275082
NZ_CP009896.1\|WP_038676158.1\|351608_351941_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|132914
NZ_CP009896.1\|WP_038676165.1\|358075_359572_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225443
NZ_CP009896.1\|WP_038676156.1\|349075_351448_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|274800
NZ_CP009896.1\|WP_038676184.1\|371580_371829_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP009896.1\|WP_038676169.1\|364335_365487_+\|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl\|CDD\|236134
NZ_CP009896.1\|WP_038676179.1\|370727_371159_-\|ImmA/IrrE-family-metallo-endopeptidase	unknown	unknown	gnl\|CDD\|368753
NZ_CP009896.1\|WP_038676161.1\|353474_355775_+\|sodium-translocating-pyrophosphatase	unknown	unknown	gnl\|CDD\|234827
NZ_CP009896.1\|WP_141267646.1\|370135_370579_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_082003894.1\|348357_348906_+\|flp-pilus-assembly-TadE/G-like-family-protein	unknown	unknown	gnl\|CDD\|274799
NZ_CP009896.1\|WP_038676168.1\|363679_364339_+\|dTMP-kinase	unknown	unknown	gnl\|CDD\|234814
NZ_CP009896.1\|WP_052138123.1\|365497_367054_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|312032
NZ_CP009896.1\|WP_038676163.1\|356639_358019_+\|Ig-like-domain-repeat-protein	unknown	unknown	gnl\|CDD\|379864
NZ_CP009896.1\|WP_038676167.1\|360764_363473_+\|type-I-DNA-topoisomerase	unknown	unknown	gnl\|CDD\|236048

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038676160.1\|351985_353341_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|185378	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional.	8.30265e-68
NZ_CP009896.1\|WP_052138122.1\|359600_360653_+\|DUF2510-domain-containing-protein	gnl\|CDD\|378480	pfam10708, DUF2510, Protein of unknown function (DUF2510). This is family of proteins conserved in Actinobacteria. Many members are annotated as putative membrane proteins but this could not be confirmed.	1.81272e-08
NZ_CP009896.1\|WP_052138121.1\|355777_356575_+\|DUF2817-domain-containing-protein	gnl\|CDD\|349475	cd06904, M14_MpaA-like, Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins. Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A (MpaA) and related proteins. MpaA is a member of the M14 family of metallocarboxypeptidases (MCPs), however it has an exceptional type of activity, it hydrolyzes the gamma-D-glutamyl-meso-diaminopimelic acid (gamma-D-Glu-Dap) bond in murein peptides. MpaA is specific for cleavage of the gamma-D-Glu-Dap bond of free murein tripeptide; it may also cleave murein tetrapeptide. MpaA has a different substrate specificity and cellular role than endopeptidase I, ENP1 (ENP1 does not belong to this group). MpaA works on free murein peptide in the recycling pathway.	7.16665e-43
NZ_CP009896.1\|WP_038676171.1\|367363_368650_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.00408e-22
NZ_CP009896.1\|WP_038676181.1\|371161_371488_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.02091e-07
NZ_CP009896.1\|WP_038676173.1\|368775_369561_+\|TIGR04255-family-protein	gnl\|CDD\|275082	TIGR04255, hypothetical_protein, TIGR04255 family protein. Members of this uncharacterized protein family are found broadly but sporadically among bacteria and archaea, including members of the genera Mycobacterium, Nostoc, Acinetobacter, Planctomyces, Geobacter, Streptomyces, Methanospirillum, etc. The function is unknown.	2.47999e-07
NZ_CP009896.1\|WP_038676158.1\|351608_351941_+\|STAS-domain-containing-protein	gnl\|CDD\|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	1.6255e-29
NZ_CP009896.1\|WP_038676165.1\|358075_359572_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225443	COG2890, HemK, Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis].	2.73579e-20
NZ_CP009896.1\|WP_038676156.1\|349075_351448_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|274800	TIGR03817, DECH_helic, helicase/secretion neighborhood putative DEAH-box helicase. A conserved gene neighborhood widely spread in the Actinobacteria contains this uncharacterized DEAH-box family helicase encoded convergently towards an operon of genes for protein homologous to type II secretion and pilus formation proteins. The context suggests that this helicase may play a role in conjugal transfer of DNA.	0
NZ_CP009896.1\|WP_038676184.1\|371580_371829_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	4.56704e-06
NZ_CP009896.1\|WP_038676169.1\|364335_365487_+\|DNA-polymerase-III-subunit-delta'	gnl\|CDD\|236134	PRK07940, PRK07940, DNA polymerase III subunit delta'; Validated.	5.47503e-155
NZ_CP009896.1\|WP_038676179.1\|370727_371159_-\|ImmA/IrrE-family-metallo-endopeptidase	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	7.97246e-06
NZ_CP009896.1\|WP_038676161.1\|353474_355775_+\|sodium-translocating-pyrophosphatase	gnl\|CDD\|234827	PRK00733, hppA, membrane-bound proton-translocating pyrophosphatase; Validated.	0
NZ_CP009896.1\|WP_082003894.1\|348357_348906_+\|flp-pilus-assembly-TadE/G-like-family-protein	gnl\|CDD\|274799	TIGR03816, tadE_like_DECH, helicase/secretion neighborhood TadE-like protein. Members of this small, highly hydrophobic protein family occur in a pilus/secretion-like region that usually is next to an uncharacterized DEAH-box helicase, in Actinobacteria. Members show sequence similarity to the TadE-like family described by pfam07811. The function is unknown. [Unknown function, General].	3.05185e-12
NZ_CP009896.1\|WP_038676168.1\|363679_364339_+\|dTMP-kinase	gnl\|CDD\|234814	PRK00698, tmk, thymidylate kinase; Validated.	1.56801e-78
NZ_CP009896.1\|WP_052138123.1\|365497_367054_+\|alpha/beta-hydrolase	gnl\|CDD\|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	5.05255e-30
NZ_CP009896.1\|WP_038676163.1\|356639_358019_+\|Ig-like-domain-repeat-protein	gnl\|CDD\|379864	pfam16640, Big_3_5, Bacterial Ig-like domain (group 3). This family consists of bacterial domains with an Ig-like fold.	0.000950113
NZ_CP009896.1\|WP_038676167.1\|360764_363473_+\|type-I-DNA-topoisomerase	gnl\|CDD\|236048	PRK07561, PRK07561, DNA topoisomerase I subunit omega; Validated.	0

>NZ_CP009896.1|WP_038676167.1|360764_363473_+|type-I-DNA-topoisomerase
MSHKLVIVESPAKARTIGGYLGDGFVVESSIGHIRDLPNNAADTPAKIKDKPWGRLAIDVDHDFTPYYIVPRDKKSHIAKLKQLLKDADELYLATDEDREGEAIAWHLLDELKPKGIPVKRMTFNEITRAAIQAAAANTRDLDMDLVEAQETRRILDRLYGYEVSPVLWRKVMSGLSAGRVQSVATRLVVDREKERMAFKVASYWDLEGTFDAGSKHDQRMFPAKLHSIDGTRVASGSNFGPDGQLKGKADVVHLDQRRAQALVSALADTTYDVRSVEAKPYRRSPYAPFRTTTLQQEASRKLGMSSSVTMSVAQRLYENGFITYMRTDSTTLSGSAIGAARAQVQELYGAEYLPDAPRTYANKVKNAQEAHEAIRPAGDSFRTPAQTGLKGDQFRLYELIWMRTVASQMKDAVGQSVTIRLGGAASSGEDVVFSASGRVITFHGFLKAYVEGTDDNAAKDDQETRLPNLHEGDAVSAASLSANGHETKPPARYTEATLIKELEEREIGRPSTYASIIGTILNRGYVYKKGTALVPAWIAFSVVRLLQEHFSRLVDYDFTASMETVLDDIAQGRKDRVSELSEFYYGSDRLEGLKRLVEDLGDIDAKELATFPVGTEADGIHLRVGKYGPYLEGPGDDGTAFAKRANVPDDLPPDELTVAKATELLANPAGEEIELGVDPETDLRVVAKNGRYGPYVTEVLPDDAPKSAKPRTGSLFKSMSLDTVTLADAVKLLALPRVVGVGEDGEEITAQNGRYGPYLKKGTDSRSLTSEDQIFGITLDEALKIYSQPKQRGRAAAAPPLKELGNDPVSGQPVVVKAGRFGEYVTDGEYNATLRKDDSVEEITLERAAELLAERRAKGPAKKAAKKGAKKTAAKKTTAKKTTTKKAAAKKTAAKKAAKKS
>NZ_CP009896.1|WP_052138122.1|359600_360653_+|DUF2510-domain-containing-protein
MTNAGWYPDPAGAPDTFRYWDGQAWSQMTTSQPSGGAAAATPAPATPPPATPPPATPPTPATALPPSQQPYQPQYQQQPQPTWNPTPPPGGGTGGIGGGSTGKTVGIVVAAVLVLALLGVGGFFGIRALSGDDDGDGGDKKADDPTSQATDGPTDGPTDETSSTVRPSGIQCTGGKPEPTTAPDPKATTLTGGGLTIPKLDGYTTDVRQSPAHTYADGFISQYVEVVPQKWIGLYGVGAIPRANGFEGIDTTAEIIMQCLTTNDQIYKGFKDRKDLKNEEITVDGKPAHRITSELRVDDSTLPIEGDVTTVVIVDTGDPASYGVFVGVAPIGDTARIAQEEQVIGEISVG
>NZ_CP009896.1|WP_038676165.1|358075_359572_+|class-I-SAM-dependent-methyltransferase
MLPVALAAPLREALLAADFTYDAVSDLLGPEAHQALSRNETRPGLRRTTDGSPLATLVRLFLLQAAVPVADAERALPGGLVDRLANAGALAQSVGEVAARLDVRPYGSEEGDLWVVSDLTPGLDGVPTAVTGDYVLGISPASSSLAQLTLRHDVGTALDLGTGCGVQALHLATHSDRVVATDVNQRALAIARFNAALNDVDDKVEVRDGSFFAPVAGERFDLIATNPPFVISPATGERLVYRDSGLPGDQVVEHIVRTAPDHLTDGGWCQVLANWVIEKDRPWDERLAGWLPDECDALVVQREVLDPASYVELWLKDSGHHPATGGDPATYGQRYDTWLSWLEQQGVAGVGFGWLNLRRRADVAPGALVRDLLEWPYDVEQPIAPAISAWADAALAARSLDAGTRLVLREDVVQETSGPVGGEDPATIVLRQQRGFRRARQVDTVVAAVAGACDGELAVGPLVDAVGQLLDRAPAGLHDVYLPELAELVAEGFLAPEE
>NZ_CP009896.1|WP_038676163.1|356639_358019_+|Ig-like-domain-repeat-protein
MTRALRITAVLVALLLGTGLLHPTPASAADRPGGWYDGSIGYTRVVNCFGLIQGTPYTEAGIGAYAGYWSDPDSGVPAVGQTFWIHYSVHGLGNPCLGGTYFRPRIALPPGVVFDTSQQIRCGYNGSGGPAPMQGCPGWGNLANGTYSNNRDQGLWGVAQGGRWEFQFPVRATQPVSGANLSIALDTVDGNSDSTVALRAPVYVFAVAGSGGTPATPSYQVLYDTPSTVAAAQNPDGGATPYGIVSEFQAITNNRAGVLRIEFATGLDQPIYQVEVPVPANFGASVYGWTDWAPFAGLIVPGRKNYWRGAFTPTGGTTVYGPMQTFTVASSGTGTAGTGPIGGTTGGTPGGLSGSSGAIGGSVTSLKVAARVSAKVVGKPTARRKAKVQVVVRPARGVATGAVTVTEKGRKVGSGVLRGGKVVVTLKKLKAGKHRLVVRYAGSQATSPASATVVLRVRR
>NZ_CP009896.1|WP_052138121.1|355777_356575_+|DUF2817-domain-containing-protein
MRRLLAALAATCTVVAGAAAVVPEPAGATAPAAATSTAPAAAPGTVTRTVIGHSVRGRPIRAFYRGDPGATHVLVVLGQMHGDEKAGPATARWLKKHLTPKPGTGIWVVPTMNPDGDARRTRTNARGVDLNRNWPTSGWSDARRGTRYWGGPRPASEPETRAMIAFLRKVTPDYIASIHQPLRGIGRSGRDVPWEKRLARNLHLPRRHFGVGNPSGTISPTLTGWYDSTLGRHGVATTIEYGARTSLRFRTKVAGRGIARAARVR
>NZ_CP009896.1|WP_038676161.1|353474_355775_+|sodium-translocating-pyrophosphatase
MPRPFVVDVEVTGGDLALVAIVAVIALGSLGMAVLFRSEVLRAGEGTPNMQRIAQAVQEGANAYLTRQFRTLTIFAGIAFVVLLALPAHTADGASGLQSEWGVRISRSIFFLVGAGFSGAVGYLGMSLAVRANLRVAAAANEQGRDPAMNIGFRTGAFVGMFTVGLGLLGASVVVMVFQETAPNVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQNIPEDDPRNAATIADNVGDNVGDCAGMAADLFESYAVTLVAALILGSQAFGDKGLVFPLIVPAIGALSAIAGVYLTKPRAGENGLQTINRAFYLSAAVGLVASAIAAFVYLPSEWSELGTGADADLTPQLFAAGAVAIGIVLAAAILALTGYFTGTEHRPVNDVARTSLTGHATVILSGLSVGLESAVYTAIVIGAAVFGAALLAGGTTGLALFAVALAGCGLLTTVGVIVAMDTFGPVSDNAQGIAEMSGDVSEEGAQILTELDAVGNTTKAITKGIAIATAVLAASALFASYTQSAFAEAGDVLYDDFLVYDAKLIVGALLGAGVVFLFSGLAINAVGRAAGAVVYEVRRQFREIPGIMEGTGRPEYGRVVDIVTRDSLRELATPGILAILSPIAVGFGLGVGPLAGFLVGAIASGTLMAVFLANAGGAWDNAKKLVEDGHFGGKGSEAHAATVTGDTVGDPFKDTAGPAINPLLKVMNLVSLLIVGAIVSLSYGDDKNDVVRILIALAAAAGIFAAVYISKQRSSAIDDGAAEPAATETV
>NZ_CP009896.1|WP_038676160.1|351985_353341_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MRELLSAIEARLDEPTARGLAAAVGRALRDGELTGGERLPPIRTVARELALSPTTVSAAWSILARAGAIRTAGRNGTIVAEQAQPAEGRIRRVVDPRAQFALDLSTGVPDMALLPSLTTALQALSKAGAAESYLEDPVLPALQERILADWPTPASSLAIVDGAMDAVELVVRSQLQYGDTVVVEHPEFPPALDIFEAAGVGVIGVRLDDEGVVPAELEAALAKGPRAFFLQPRAHNPTGISTTPGRAEELARVLAAAPSPVLVVEDDSAGAISTSPDVSLGAFLPERTVHVRSFGKSHGPDLRLAAVSGPDEVLAGIARLRQLGQGWSSRLLQRVLLELLSDEVALAQVATARTTYAERRAAFCAVLRRHDIEVTGRDGLNVWVPVRDESAALVRLASLGIGVMPGAPFQVFPGEGAYVRVTVGLLGDDLEEVAESVAEAAQMGSWHSRVR
>NZ_CP009896.1|WP_038676158.1|351608_351941_+|STAS-domain-containing-protein
MNLTLSTREVGGRTVVAVGGEIDVYTAPKLRDTITELVAAGTYHLVVDMVDVEFLDSTGLGVLVGGLKKVRAHDGSLELVCNADRLLKIFKITGLAKVFVIHDSADAALA
>NZ_CP009896.1|WP_038676156.1|349075_351448_-|DEAD/DEAH-box-helicase
MTAQPDLRLPATAGRRDPGALLDRLTALPGRAERLTHRREVPARAAVHADWPAWADPAVVAAYEARGIARPWAHQVAVAEAAHRGEHVVVATGTASGKSLAYLLPALSAVRAARGPRGQRGAAVLYLAPTKALAHDQWSSLHDLGLDVRVATHDGDSTPEEREWTRDHAEYVLSNPDMLHRSLLPGHERWTQFFRSLRYVVIDECHHYRGVFGAHVAQIVRRLRRVCAAYGASPTFMLASATVADPDLTARRMTGLDVTAVTADGSPRGALQVGLWEPPLTSYQGENGAPVRRPATAETADLLADLVVDDVRTLAFVRSRHGVETVAQRAGELVAEVDPSLAGRVDSYRGGYLPEERRALEDDLRSGRLLGMAATNALELGIDVSGLDAVLVTGYPGTRAAFWQQVGRAGRDAGGALGLFVARDDPLDTYLVHHPDALLGRPVEGTVFDTDNPYILGPHLCAAAQELPVTVADAALFGPRMREVLGSLVERGLLRRRAAGWYWTDRSRAADLADIRSAGGAQVQLVEGATGRVVGTVDGGRAHSTAHTGAIYLHRGQTWRVDELDLDDRVATLTRVAVDHTTTARDITDIRIVDEREHVAWGPCQVSFGTVEVTNQVTSYLRRRLRTGEVIDETPLDLPARTLSTAAVWWTVPDEVVTRMLATTGLDLADLPGAAHAAEHCSIGLLPLFATCDRWDIGGVSTARHPDTGVLTVFVHDGHPGGAGFAERGYRTAATWLRATRATIASCECASGCPSCIQSPKCGNGNDPLDKAGAVALLDALLTDAPPDVA
>NZ_CP009896.1|WP_082003894.1|348357_348906_+|flp-pilus-assembly-TadE/G-like-family-protein
MAGVLLLVGAATGVVGAIVVDHRRAQAAADLAALAAAAHPGRDPCTTAARVATANDATLRSCRRDGPDVVVTVVVQGPRWLGQEGDLTASARAGPDPAPAPARAPARAPARAPTQVPAVTPVASRPAVRLGLRRPRRRAGPGRAARGPPRPASPTARRAACAPCAASRTASCRPSSSRARGR
>NZ_CP009896.1|WP_038676168.1|363679_364339_+|dTMP-kinase
MTRYPGRYTSTGVFVCFEGGEGGGKSTQSRLLRDRLAEEGYAVRLTHEPGDTPVGKDLRRIVLSPETGALAHKTEFLLYAADKAEHVETLVLPALDRGEVVLTDRYVDSTLAYQGAGRALDRDELEEVSRWATGDLRPHLTVVLDLEPEAGLGRFEERDRIEGEGLAFHQRVRQSFLDLAAHDPEHYLVVDARRSIDEIAALIAERVAPLLVQARRLAP
>NZ_CP009896.1|WP_038676169.1|364335_365487_+|DNA-polymerase-III-subunit-delta'
MTIWDTLVGQRPTIDALEKAVAGHGMTHAWLFTGPPGSGRSNAAIAFAAALQCDQGGRGPDCPDTCHACHTVLAGSHADVSVIRTQKLSIGVDEVRDLVRRASLSPMGDRWQILIVEDADRLTDQACNALLKAIEEPNGRTVWMLCAPTVEDVLPTIRSRCRLVTLATPTTVEVAGFLQARGIEARLASYAARASQGHIGRARALAFDEDVRNRRQEVVGMPARLTTLGRCMDAATRLASAAKDEADAITAELDAREKTDLDAAYGVVERGRRPREYGPALAALEKSQRTRAKRRHLDVVDRGLTDLMSVYRDAIALATGAPGELVNEDIREQVQTIVDSSTPELNLRRIGWIFAAREQMLEFNVPVALALESMMVALKAPQR
>NZ_CP009896.1|WP_052138123.1|365497_367054_+|alpha/beta-hydrolase
MSKKLIVAVVVVWALVLAGGVGIGVVLLTRGDDDSGKPGADGSTPPSTKTQGPDGRTIEDFYQQKLSWSACGSNECTTLEVPIDYQKPGDGSIELALERTKATGTRIGSLVINPGGPGAPGTSTVRDAQYYFAPELMAAYDIVGFDPRGTGKSAPVDCLSDSALDAYIAADPDPDTPEEVKQAEENSADFWAGCKARSGTLGGHVSTVEAARDMDVLRAALGEDKLDYLGFSYGTRLGATYAELYPENTGRLVLDGAIDPSLSSRDGALSQAAGFETALRSYVQSCVDAGSCFLGDSVDAGLSTIKGLLDTIDKEPLTTKDPEGRKLTVGLAFYGLITPLYAKDNWSYLDDGLKAALDGDGSTLLTLADFYGSREGGRYTDNSLEAISVINCLDDPWSITPDEVPGQFSDFEKASPTFGKVFAWGLTACDGEPFTSTDEPDLKIDGSGAAPIVVLGTTRDPATPYKEAVAMAQQLESAVLVTREGDGHTAYNKGNSCIDDAVHAYLIEGTVPRDGLKC
>NZ_CP009896.1|WP_038676171.1|367363_368650_+|site-specific-integrase
MARTRTPKKRTYAEGSVYQRCDERRGCPPTTGAGRPAHRCSGPWVGAFVHGFTERGTRRRYTVKGDTEAQARTRMRKRMGEVLDGGGAAASSKTTVKQWAEEWLDIVERELRPQPFTSARSAVRRWIVPTIGHKRLSDLAPADVRKVANAQRSAGLKPSSQRRTHSVLITMLKAARADGYAVPSIVVEVKAPAAGPSDRSDLPLDLAVEILGVAAEIPQGSRWVAALLQGLRQAEALGLTWDEVDLERGLLTISWQLQPLPYRFPRDRSSGFRVPDGYEARQVKGRWHLVRPKTRAGWRVIPLVPWMVTSLKAWREIAPESEHGLVWPTLDGGPCDPKLDDVEWYALQETVAAQRGADVQHPAGRPFTIHEARHTTATLLLEAGVDPAVIIAILGHSSMLSTKGYLHVKTAPLAAAMAAVAERLQLAA
>NZ_CP009896.1|WP_038676173.1|368775_369561_+|TIGR04255-family-protein
MTTGQESLKFKTPPVKTVVLTVYFEALETLQPIHLSMLRERWRDYYPSVGSLPPLRAHPHAGSGTTGGDDNVPSWPFPYMIFATVDETEAIAIQNDRLIRTWGFSDGASYPGYQTLSRDLRQRLGEFAEVVKVELDRELTLTSSDCRYSNHLGEADIADLLVGVASSWSGTSNGAALDNVHYAGLRLHIDNPDDPASHVYIDVDTYEDGAELEITSRYEIVVPEGDSSAELGGLDKAHDALLGAFERFTSASMKSDWGQEQ
>NZ_CP009896.1|WP_038676175.1|369557_370139_+|hypothetical-protein
MTAQIVEDVYRREQVEGIWSRKHPPSKAPCRLIATKPQDGVDYTLPAARISTRWKLYTAGVWSGRSVGFEYAKWQLVQITEHHIEQGLEMPDRAAEALMLHHLRSLVQPGTLYPTMSVEDGDVIAEWRVGEYGLELLTTASSARWTLRRRGVRISRSTSMLGLKTLLTSFTAAADELNPDWPALFPQAAQHAR
>NZ_CP009896.1|WP_141267646.1|370135_370579_+|hypothetical-protein
MSEAVVWDDPGIPPDEMLLRRIPRHPDFRVPDVLSGRLLIKKSALRYNPDGMSVQADSLLPVAGVARHEIYNWETHNGIEFPVDAARRTEQAGVVAEPDPDDERLGEAHASVRLRPDCADKKGDWDDVRAVIAEEARLMPEDPNPPE
>NZ_CP009896.1|WP_038676179.1|370727_371159_-|ImmA/IrrE-family-metallo-endopeptidase
MKNTYSPWDELASLPHIDLVWERLSDRKGEYRHWEQRIALDPRMRRHQARSVLCHELRHVAACDVVTHCGRTNLLQERRADRDAARLLVDVHDLGEVVAAHGEHHPTLARDLGVSLHIVRTRLANLHPSELHYLRGRQGAIGA
>NZ_CP009896.1|WP_038676181.1|371161_371488_-|helix-turn-helix-transcriptional-regulator
MTEQDSRDFAAALGAEIASWRKRRKLSRGDLGALVDLSETTIGRIERGNVAAAAATADVWRISAALGLTFSDLVRRAEEAINLSGPRENLGAVASTEAGDFEPGDLED
>NZ_CP009896.1|WP_038676184.1|371580_371829_+|helix-turn-helix-transcriptional-regulator
MTSHIDPEAVAIGRAVHGAIITAGFTLVEAAERTGIGYRTLSRRVNGTLPFTFPELARIATLCGVKVSDLAAAAERISASAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_2

765799-765892

Orphan

Consensus_repeat	Method
GGCAGTTTCACCGCCTAGGCGGTGAAACTGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_2

>merge|NZ_CP009896|2|765799-765892|CRISPRCasFinder
GGCAGTTTCACCGCCTAGGCGGTGAAACTGCCGGTTGGCGTCGGGATATCCGTGCGCTAAGGGGCAGTTTCACCGCCTAAGCGGTGAAACTGCC

>NZ_CP009896|2|2|765799-765892|CRISPRCasFinder
GGCAGTTTCACCGCCTAGGCGGTGAAACTGCC	GGTTGGCGTCGGGATATCCGTGCGCTAAGG
GGCAGTTTCACCGCCTAAGCGGTGAAACTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_075018722.1\|760501_760966_+\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|225155
NZ_CP009896.1\|WP_038676708.1\|765956_766508_+\|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|132028
NZ_CP009896.1\|WP_038676718.1\|773027_773789_+\|cytochrome-C-biogenesis-protein-CcdA	unknown	unknown	gnl\|CDD\|280792
NZ_CP009896.1\|WP_082003532.1\|759416_760505_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133030
NZ_CP009896.1\|WP_038676710.1\|766501_767866_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_082003905.1\|773866_775384_+\|cytochrome-c-biogenesis-protein-ResB	unknown	unknown	gnl\|CDD\|377471
NZ_CP009896.1\|WP_052138203.1\|768964_770188_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381602
NZ_CP009896.1\|WP_038676697.1\|757173_757422_+\|glutaredoxin-family-protein	unknown	unknown	gnl\|CDD\|368604
NZ_CP009896.1\|WP_038676695.1\|755572_757177_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341259
NZ_CP009896.1\|WP_038676721.1\|775380_776400_+\|c-type-cytochrome-biogenesis-protein-CcsB	unknown	unknown	gnl\|CDD\|274447
NZ_CP009896.1\|WP_052138202.1\|763099_764098_+\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NZ_CP009896.1\|WP_038676701.1\|758001_759498_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_141267153.1\|757441_758005_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038683405.1\|767888_768875_+\|porphobilinogen-synthase	unknown	unknown	gnl\|CDD\|236450
NZ_CP009896.1\|WP_038676716.1\|772453_773035_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_CP009896.1\|WP_038676704.1\|761795_763103_+\|glutamyl-tRNA-reductase	unknown	unknown	gnl\|CDD\|234592
NZ_CP009896.1\|WP_038676706.1\|764094_765783_+\|uroporphyrin-III-methyltransferase	unknown	unknown	gnl\|CDD\|223086
NZ_CP009896.1\|WP_038676712.1\|770442_771765_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|234607
NZ_CP009896.1\|WP_038683401.1\|761067_761799_+\|redox-sensing-transcriptional-repressor-Rex	unknown	unknown	gnl\|CDD\|235486
NZ_CP009896.1\|WP_038676714.1\|771761_772457_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_075018722.1\|760501_760966_+\|GtrA-family-protein	gnl\|CDD\|225155	COG2246, COG2246, Predicted membrane protein [Function unknown].	3.44837e-13
NZ_CP009896.1\|WP_038676708.1\|765956_766508_+\|SigE-family-RNA-polymerase-sigma-factor	gnl\|CDD\|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	4.9302e-35
NZ_CP009896.1\|WP_038676718.1\|773027_773789_+\|cytochrome-C-biogenesis-protein-CcdA	gnl\|CDD\|280792	pfam02683, DsbD, Cytochrome C biogenesis protein transmembrane region. This family consists of the transmembrane (i.e. non-catalytic) region of Cytochrome C biogenesis proteins also known as disulphide interchange proteins. These proteins posses a protein disulphide isomerase like domain that is not found within the aligned region of this family.	1.22243e-39
NZ_CP009896.1\|WP_082003532.1\|759416_760505_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	6.30578e-81
NZ_CP009896.1\|WP_082003905.1\|773866_775384_+\|cytochrome-c-biogenesis-protein-ResB	gnl\|CDD\|377471	pfam05140, ResB, ResB-like family. This family includes both ResB and cytochrome c biogenesis proteins. Mutations in ResB indicate that they are essential for growth. ResB is predicted to be a transmembrane protein.	3.51949e-150
NZ_CP009896.1\|WP_052138203.1\|768964_770188_-\|hypothetical-protein	gnl\|CDD\|381602	cd13399, Slt35-like, Slt35-like lytic transglycosylase. Lytic transglycosylase similar to Escherichia coli lytic transglycosylase Slt35 and Pseudomonas aeruginosa Sltb1. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).	2.93973e-22
NZ_CP009896.1\|WP_038676695.1\|755572_757177_+\|AMP-binding-protein	gnl\|CDD\|341259	cd05936, FC-FACS_FadD_like, Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD. This subfamily of the AMP-forming adenylation family contains Escherichia coli FadD and similar prokaryotic fatty acid CoA synthetases. FadD was characterized as a long-chain fatty acid CoA synthetase. The gene fadD is regulated by the fatty acid regulatory protein FadR. Fatty acid CoA synthetase catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, followed by the formation of a fatty acyl-CoA. This is a required step before free fatty acids can participate in most catabolic and anabolic reactions.	1.00483e-147
NZ_CP009896.1\|WP_038676721.1\|775380_776400_+\|c-type-cytochrome-biogenesis-protein-CcsB	gnl\|CDD\|274447	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB. Members of this protein family represent one of two essential proteins of system II for c-type cytochrome biogenesis. Additional proteins tend to be part of the system but can be replaced by chemical reductants such as dithiothreitol. This protein is designated CcsB in Bordetella pertussis and some other bacteria, resC in Bacillus (where there is additional N-terminal sequence), and CcsA in chloroplast. We use the CcsB designation here. Member sequences show regions of strong sequence conservation and variable-length, poorly conserved regions in between; sparsely filled columns were removed from the seed alignment prior to model construction. [Energy metabolism, Electron transport, Protein fate, Protein modification and repair].	1.70239e-79
NZ_CP009896.1\|WP_052138202.1\|763099_764098_+\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	5.04358e-126
NZ_CP009896.1\|WP_038676697.1\|757173_757422_+\|glutaredoxin-family-protein	gnl\|CDD\|368604	pfam05768, DUF836, Glutaredoxin-like domain (DUF836). These proteins are related to the pfam00462 family.	5.42674e-22
NZ_CP009896.1\|WP_038683405.1\|767888_768875_+\|porphobilinogen-synthase	gnl\|CDD\|236450	PRK09283, PRK09283, porphobilinogen synthase.	0
NZ_CP009896.1\|WP_038676716.1\|772453_773035_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	2.44711e-39
NZ_CP009896.1\|WP_038676704.1\|761795_763103_+\|glutamyl-tRNA-reductase	gnl\|CDD\|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	4.4162e-144
NZ_CP009896.1\|WP_038676706.1\|764094_765783_+\|uroporphyrin-III-methyltransferase	gnl\|CDD\|223086	COG0007, CysG, Uroporphyrinogen-III methylase [Coenzyme metabolism].	1.00155e-65
NZ_CP009896.1\|WP_038676712.1\|770442_771765_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|234607	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase.	0
NZ_CP009896.1\|WP_038683401.1\|761067_761799_+\|redox-sensing-transcriptional-repressor-Rex	gnl\|CDD\|235486	PRK05472, PRK05472, redox-sensing transcriptional repressor Rex; Provisional.	1.23939e-113
NZ_CP009896.1\|WP_038676714.1\|771761_772457_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	2.38189e-40

>NZ_CP009896.1|WP_038676706.1|764094_765783_+|uroporphyrin-III-methyltransferase
MTRATAAKKAAPTPAAPQAAQPGGVAFVGTGPGDPDLLTVRAVKLIEDADVIITEDAGHADMVRIIRNRAAANRVVAPGEQPVEPVEAEIVDGGFGEDGQPLTHAARAKVVVKQAKRGLRVVRLLGGDPFLYASGPEEAQAVAKANLGFEVVPGVSSVAAVPAYAGIPLTTKDHREMAVVTCGDKVDWSRYADTPTLVLLSAVGQIGDIAKQLVAIGRSPQTPVAMTRVGTTTEQQTITSTLEHIAADARAARISPPAIVVIGAVVDLREKLSWFETKPIFGWRVLVPRTKEQSASLSNRIREFGGVPEEVPTISVEPPRNPQQMDKAVRGLVEGRYEWIAFTSVNAVKAVREKFEEYGLDARAFSGLKIAAVGDKTAQAIADWGLRADLVPSGEQSAAGLLEVWPEYDEVLDPINRVFLPRADIATENLVAGLIDLGWECDDVTAYRTVRAAPPPAPTRDAIKTGKFDAVVFTSSSTVRNLVGIAGKPHPSTIIAVIGPATAKTAEEHGLRVDVLAPKPDVELLVEALAGFGADRRAALLEAGEPVTKPSDRKPSARRRKA
>NZ_CP009896.1|WP_052138202.1|763099_764098_+|hydroxymethylbilane-synthase
MTLRIGTRRSTLATTQSGHVAAALTEKLGVPTTLVEITTDGDRSQAAGTSLVGAPSTGVFVSALRDALLAGEVDVAVHSLKDLPTYPTEGITLAAIPPREDPRDVIVARDGLTLGELPPGSKVGTGSPRRVAQIEALGLGVELLGLRGNVDTRIGRVREGVLDAVVLARAGLARLGRLDDVTEVLDPLQVLPAPGQGALAVECRSDDTATLAALAVLDDPATRAAIHAERTVMAVLEGGCAAPIGALADLAEGDDGPELWLRAVVLTADGGLSVRRSAAAPLGADPAGWPAAGTALGEALAAEMLADGAAELLATPESTSHPSARSAEVHNA
>NZ_CP009896.1|WP_038676704.1|761795_763103_+|glutamyl-tRNA-reductase
MSVLVVGISHNSAPVSLLEQVALDDDGVHKLMADAAACEHVTEATVIATCNRLEIYTEVERFHGSIEQLSRLLVDRAGGTTEAMLPHLYVHYDDGAISHLFQVAAGLDSMAVGEGQILGQTREALRRGQELGTVGPALNSLFQQALRVGKRTRAETEIDQVAPTLVSAALDETAKTVGPLEGKYVVVVGAGAMAGLATATAQRLGAGHLAIVNRSVDRAVRLAVQYAGQAVRLADLGDELGRADVVISCTGSSGTVVDRAQLEAARAGSDRPLALIDLALPHDIALDVVDLPGVSRVGLAELAEVLHGGPTGREVQEVRRILGEEVTAFLAARRQASVTPTVVALRSMATSVVDAEMTRLDARLPDLDEATRAEIRHTVRRVADKLLHEPTVRVKELANEQGAVSYAAALAELFALDPEAVDAVTRPVVVEEGTS
>NZ_CP009896.1|WP_038683401.1|761067_761799_+|redox-sensing-transcriptional-repressor-Rex
MESGAVTTRSSTDAARVIPEATVARLPVYLRALTALADNGIRTCSSEDLATAAGVNSAKLRKDLSYLGSYGTRGVGYDVDYLRYQIAREIGVTQDWPVVIVGIGNLGHALANYSGFRSRGFRVVALLDADPALVGRTVADIAVRPFDDLDEIVREHDVAIGVIATPAHAAQDVADRMVGIGITSILNFAPAVVAVPEGVDVRKVDLSIELQILAYHEQRKANGGAEAAAAAADGVDAAGGGAA
>NZ_CP009896.1|WP_075018722.1|760501_760966_+|GtrA-family-protein
MSDHGHRATAVRFAAVGVCNTAIDTVVFVLLHGSLGITLANFVSSSAGMVFSFVVNGLFTFRAERLTLRHAVLFVASTGLVMWVAQPLLIHGWLWLLERGPDVALGGMGAGDVRIWVAKLASIACSLVLNFLAYRFVVWPVEHRGDEAPVPPAM
>NZ_CP009896.1|WP_082003532.1|759416_760505_+|glycosyltransferase-family-2-protein
MARPVPGAAQRRHGGRRGRADRRGDPLGSTSCTTTPPPSGPRRVAYVLPVYNEEENIGVFHAALVEATDKRPDLAFEFVYVDDGSRDASLERLVDLRAQDPRVSVVQFSRNFGHQLAVTAGLDLVAQAGDADAVIVMDTDLQDPPRVSLEMIERWEAGVDVVYAQRRTRKDTPFKRATAWGFYWVLDRLASIEIPRNVGDFRLMDARVVAEVSRYREHDRFLRGIVAHVGFRQEALLFDRDERHAGETGYPLRKMLNFAASGILGFSTTPLKMISRFGFAISAFSLLLGCYVLFVRVFKPDESVPGWAFLGVGMFMLSGIQLIMMGVIGSYLGRVYIETQDRPLYTLAMVARDGTGSKGAVR
>NZ_CP009896.1|WP_038676701.1|758001_759498_+|hypothetical-protein
MTRLLAARPTWLPRYDVLLGWLVVAHVVAKIVIFPLVMDAAPHGDEQAYLNGGMALSNAVRDLFGFTSPDSAELERNVVASGWFMPGMPILVAPVYLLFPDAPMWLVRGYLGLVTLALFITVLRVVARRIGPGWACVIAVFPGLIPSWIVFTYASWGDLCAGLLLVLLVAHLFTMFRGLRQGEAPTLREGLVLGLLAIVVLYLRSSTSVLLAALGLLTLVAAVLLLRGRVRLRALGAAGLAGFVFVVLLAPWSIYASQTLDGRVITTTTVPTVMANTFGDRKEVCFGPCDPDSTLWFRPLRYARELGRATDTSEVDTLKVMSDYATRDLTASHYLDQVVHNLGAYSLQPTNFTRYLAPPEGRGAFGRAGELTADIFTWALYVPMFVLGLVSLLFQARRSIEARVLDVLTKVALGGLLIQPFVHIAGGRYWTTAAPMLAIGAFSLLRERELARSGAPRAPDGVVGANDVAVERWLGRFQVLLSAATAVVVVVLIGAAIL
>NZ_CP009896.1|WP_141267153.1|757441_758005_+|hypothetical-protein
MGVSPLLPARARWVVGGVATVVVLVLLLLSHEFGRAEPTNNYRPLLPPDALATGCFPLPDGAQLDLPHQIRRDGDHATPDGERRELRGQYDLVDRDEALARIVGAFTAVGFTEGPREDDGDGVAVVLTKGDQSVRALVTELPDTSADTLVRGEFVLDLPVVAAAQDDPVCSDPKSTKRWPEKGEATR
>NZ_CP009896.1|WP_038676697.1|757173_757422_+|glutaredoxin-family-protein
MSAPVPRVTLYGRPGCHLCDDARAVIEAVCAELGESYTEVSIDDDPALADRFAHEIPVTFVDGRQHDFWRVSPDRLRRALQG
>NZ_CP009896.1|WP_038676695.1|755572_757177_+|AMP-binding-protein
MSQQDAPATPDVAALVAAAAADHPDRLAVVEAGGRGLTWAELDDEVSRVATGLGAAGVLAGHRVMIVLGNRIEFVTTYLGVLRAQAVAVPVNPGSTVVELAGMLVDSGSRMVVVDERTAVPVRSAVGRSEVAAAAHDESRPLPRLVVLGEPAPDELAYDDLRAEEPRPVPPLLDPEKLAVLLYTSGTSGLPRAAMLTHRALLANVDQVATVEPPMIHSDDVVLGVLPLFHVYGLGAVLGGVIRHRAKLVLTDRFDPEGTLDLIEDEACSVVPVAPPVFAAWRHVDALAERLGPVRMILSGSAPLPAETVEEFSAAVRVPVHQGYGLTEASPVVTSTLRSATVKPGSVGAALDGIELRLVDDEGVPVDGSAADDPGEIQIRGRNLFSGYWPEGADGPGADGWWSTGDVGFLDADGDLFLVDRVKELIIVSGFNVYPSEVEAVLGEVAEVRQAAVLGTPDEHTGEAVVAYVVPDDPAADPESVAAAVRARAEEHLAPYKRPVRVEVVETLPRTVTGKIRKGQLRGQERRKALGILE
>NZ_CP009896.1|WP_038676708.1|765956_766508_+|SigE-family-RNA-polymerase-sigma-factor
MPERRDEDAFVAFAQGARGRLRSTAYLLCGDWDRAADHVQEALIRVYVAWPRLTKAGREYGYARKALVSVVLDHARRRSSTEVVADVDASIGAGYSVDSGYDLAEQVTARAALLAVLADLPPRQRACVVLRYFEDLSVADAARALGCSEGTVKSQTARALDRLRSVFEDSPLGELTVGGGTSW
>NZ_CP009896.1|WP_038676710.1|766501_767866_+|hypothetical-protein
MVNDVRALLQEAVADPPGDETDLSAVLLGGRQRVRRRRGGGVLGSTVALGVAAATLTLVTSGGADPGRVAEHRVPRPEGPVLRVSDAGTAVEGRDYDLLASYTNRDLESRNGQYFDGVTDDGLILFRDGPHGLRNRVRWALRDPATGVNDWLPDPPAGVDQPRALRLGADRLYFLATPLDGRGPFRLLVLDRATRTWSTLVWPGLPRAEEYDAAFGPDGRIYVGVQAAAASPPPGGWPTGPDGEADDAAAEDDTNDLWSVAPGDLADVRDEKTRVGVFTFTESALVWTTQRDGTREQVHVRDLRTGAEHDFDPRLGARCNVLSFRASGDRIVIGQYCGTYDDGRDDRIQVLTTDGETVTTLQGDSIDGWLADGSGDGHLVQVRAWRPDQEGDLVYDLDTDRLLRVSDSVSSWSMGGPVPAGSLLVDRAYGEDGGSSASMIPDKGAVQWLIRWRS
>NZ_CP009896.1|WP_038683405.1|767888_768875_+|porphobilinogen-synthase
MRPVVRPRRLRTTAAMRDLVAETTLRPSQLVLPAFVREGASEPIPIGSMPGVVQHTRDSLRKAATEAAEAGLRGIMLFGVPETKDAVGSGATDPDGILNVALADVAAEVGDALVVMSDLCLDEFTDHGHCGVLDAAGRVDNDATLERYAEMAVVQARAGAALVGPSGMMDGQVAVVRDALDEAGFTDTGILAYSAKYASAFYGPFREAVDSALQGDRRTYQQDGRRNAREGVREMLLDLEEGADIVMVKPALAYLDVLRQVADAAGELGVPVAAYNISGEYSMVEAAAANGWIDREAAILETLTSIRRAGADMILTYWATEAAGLLQR
>NZ_CP009896.1|WP_052138203.1|768964_770188_-|hypothetical-protein
MTRKRLGRLQRAATIIPLALLSAAWTASVAGIGGVSAPVAAAESPGQVTDGTSVPEESIEDPASLSDPATVEGIDDGNEAGIVSAASTNAIPAAALAAYQRAETVINSADKTCNITWQLIAAIGRVESDHGRVGGNVLNDDGMATPGVFGPALNGRKGTKAISDTDAGVYDNDPQWDRAVGPMQFIPSTWQVVGVDADDDGRRDPQDIDDAALAAAVYLCSGDGDLSTVVGQRAAVYRYNHSQAYVDLVLKIMNAYLEGDFTSVPNNSTAAGYIVPEPPSFGVDGPKNIKPGKNGSKGGGKGSTGGGTDTPGTGTPGGTPTNPGNPGNPGGKPTTPPTKPTPPKTPLDPVVEGVDEGVGAVTSGLISGVLGLLTKQEAADACRAEYPKLTQTVQLLGCLVSYGLKTP
>NZ_CP009896.1|WP_038676712.1|770442_771765_+|glutamate-1-semialdehyde-2,1-aminomutase
MPAPLTSGSEALFARARAVTPGGVNSPVRAFNAVGGTPRFIREATGPWLTDVDGNTYVDLICSWGPMLLGHAHPAVVEAVQTAAARGSSYGTPTEGEVALVEAIVARTPVERLRLVSSGTEATMSAIRLARGFTGRDVVVKFAGCYHGHVDSLLAAAGSGLTTFSLPGTPGVPASSTELTLVLPYNDRAAVTAAFAEHGDRIACLITEAAPGNMGVVPPAPGFNQFLAETCRAHGALFVSDEVMTGFRVSKAGQWGTDGAVEGWAPDLMTFGKVMGGGFPAAAFGGRADVMSHLAPEGPVYQAGTLSGNPVATAAGLATLTAADDAVYDRIGVVADALRAGIAETFTAAGLPHVIQSTGSMFSVFLTDAPVTSYDEAQRTDVAAYGALFHAMLDQGVHLPPSAYEAWFVSSSHDDRAVQQVLDALPAAATAAAAAQGGTR
>NZ_CP009896.1|WP_038676714.1|771761_772457_+|histidine-phosphatase-family-protein
MTTPDTVVHLVRHGEVHNPGGILYGRRDGFHLSVRGRAMADRVADHLQGNDVTLIRSSPLERARETAAPLAAALGLEVGVEPRVIESENRFEGMTFGKGNNALRNPLLWRHLYNPFKPSWGEPYRAIVERMMAAVHDARRDAAGHEAVLVSHQLPIWTTRLSVEGRSFLHDPRKRQCTLCSVTSFGFAGDDLVQVSYAEPAIDLIPTGDIAAPFSAGDAPEENKPEGTPPA
>NZ_CP009896.1|WP_038676716.1|772453_773035_+|TlpA-family-protein-disulfide-reductase
MTRSTRPVRALLLVGLVLLASACSKIEGTGDLNFVKGDGQVVEVAQGDREKPLDFGGTTVQGEPLDITDLRGKVVVLNVWWSGCGPCRAEMPMLVEAEKELGKDQVSFVGINIRDLAPETAEAFERDRGVDYPSLYDPGSETLLKMGRYAPYAPPATLVLDREGRVAALINGPIPSKGTLTTVVEDTLAESDG
>NZ_CP009896.1|WP_038676718.1|773027_773789_+|cytochrome-C-biogenesis-protein-CcdA
MGEWFQEQAVAGSLGVAVPVAMIAGLVSFFSPCVLPLLPGYLSYATGLSGADLAAGEATRRRGRMLLGSLLFVLGFAVVFVLMGAAFGSLGPWLRRWDTEIQVGLGVLLIVLGLVFAGALPWLQRDVRIHKIPSVGLGAAPLIGALFAIGWTPCVGPTYGAIIGLTYTDATAMRGALLSLFYALGLGIPFIVAGLAYRRTLAVTGFVRRHQKWVMRIGGGFLVLIGILMVTGWWTYLVQWLQLQLVQNFEVVV
>NZ_CP009896.1|WP_082003905.1|773866_775384_+|cytochrome-c-biogenesis-protein-ResB
MRTALMLLLLLALAAIPGSVIPQEDVDSLAVTRWKSEHPKLTPYYEKLDLFGVYSSPWFSAIYLLLVISLVGCIVPRLLVYYRAMRAQPPAAPRHLTRLPVHTTYLTEASADDVLGRARTLLGKRHRVRPAAEGDDYVAAERGYLREAGNLVFHLSLLIVLAGVGMGGLWGYQGGVILVEGTTFSNNLTQYDDFKPGSLFRQDQMKNFRFSVDKFSVDWLKSGPRAGQAREFQAALTYHVDDGPAKKYDLRVNHPLEIDGTDVFLIGHGYAPVITVRDGEGNVAYTGPTVFLPQDASFLSYGVIKAPTAKPGQIGLDGLFYPTFEMIDGNPVTVFGDDLLPTLSMLAWTGDLGLDTGASQSVYVLDKSKATQVKKKDGKPFRVDLQVGDTVKLPDGLGTVTFDRVDPWIRVQISQTPGKEIALGGVILALIGLCASLFLRPRRVWVRALPAPATTGAGPDDGDAEGTMNGTGGTLVEIAVLDRSGNGEMDEVLAALVQQLQEAAK
>NZ_CP009896.1|WP_038676721.1|775380_776400_+|c-type-cytochrome-biogenesis-protein-CcsB
MSNTAWETLSNQAVGMAGIVYFIALIVHLAEWASLRQPARDRELVAAGADGAAVVAPAEESAGHAQRVAFLGRLGFLLTAIGCAVHFVALLGRGMAADPNRVPWGNMYEFTLSGTFVVALLYVVLYKKLGLAWMGPIVVTFIVATLMVAVIWLHDEVAPLTEALNSPWLVIHVVSAIIATGAFTLGGIASIMYLVRMRAERRARGAERELTGWVARVPQLDALDRLAYRVHAFAFPVWTFAVLITGPIWAHEAWSRYWNWDPKEVWAFITWVVYAGYLHARATAGWKGRKAAMLAIVGLATLWFNFIGINYFSTTSQHSYAAERIVGTVTAPASLVVRF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_3

1008314-1008403

Orphan

Consensus_repeat	Method
GTTTCACCGCCTAGGCGGTGAAACTGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_3

>merge|NZ_CP009896|3|1008314-1008403|CRISPRCasFinder
GTTTCACCGCCTAGGCGGTGAAACTGCCGGTGGGCCCAGCGAATTCCGTGAGCCAACGTCCGGTTTCACCGCCTAGGCGGTGAAACTGCC

>NZ_CP009896|3|3|1008314-1008403|CRISPRCasFinder
GTTTCACCGCCTAGGCGGTGAAACTGCC	GGTGGGCCCAGCGAATTCCGTGAGCCAACGTCCG
GTTTCACCGCCTAGGCGGTGAAACTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_082003548.1\|1004645_1006028_+\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
NZ_CP009896.1\|WP_038677067.1\|1014811_1015765_-\|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|143587
NZ_CP009896.1\|WP_052139230.1\|1002667_1003870_+\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
NZ_CP009896.1\|WP_052138252.1\|1006227_1006842_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038677062.1\|1009166_1010000_+\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224995
NZ_CP009896.1\|WP_038677050.1\|999892_1001137_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038677058.1\|1003872_1004649_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|181113
NZ_CP009896.1\|WP_038683519.1\|1006024_1006228_+\|ferredoxin	unknown	unknown	gnl\|CDD\|224064
NZ_CP009896.1\|WP_082003547.1\|997573_999646_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379868
NZ_CP009896.1\|WP_038677060.1\|1006838_1008299_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|275104
NZ_CP009896.1\|WP_141267140.1\|1010474_1011167_+\|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl\|CDD\|225002
NZ_CP009896.1\|WP_052138255.1\|1013794_1014442_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP009896.1\|WP_038677063.1\|1010001_1010391_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|223672
NZ_CP009896.1\|WP_052138254.1\|1011534_1013550_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|237030
NZ_CP009896.1\|WP_141267139.1\|1015971_1016385_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038677066.1\|1014404_1014815_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038677061.1\|1008423_1009170_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|236094
NZ_CP009896.1\|WP_082003550.1\|1016694_1018071_+\|LCP-family-protein	unknown	unknown	gnl\|CDD\|367673
NZ_CP009896.1\|WP_038677052.1\|1001133_1001982_-\|LLM-class-F420-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274680
NZ_CP009896.1\|WP_038677054.1\|1002050_1002638_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_082003548.1\|1004645_1006028_+\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.09836e-65
NZ_CP009896.1\|WP_038677067.1\|1014811_1015765_-\|carbon-nitrogen-hydrolase-family-protein	gnl\|CDD\|143587	cd07197, nitrilase, Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes. This superfamily (also known as the C-N hydrolase superfamily) contains hydrolases that break carbon-nitrogen bonds; it includes nitrilases, cyanide dihydratases, aliphatic amidases, N-terminal amidases, beta-ureidopropionases, biotinidases, pantotheinase, N-carbamyl-D-amino acid amidohydrolases, the glutaminase domain of glutamine-dependent NAD+ synthetase, apolipoprotein N-acyltransferases, and N-carbamoylputrescine amidohydrolases, among others. These enzymes depend on a Glu-Lys-Cys catalytic triad, and work through a thiol acylenzyme intermediate. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer. These oligomers include dimers, tetramers, hexamers, octamers, tetradecamers, octadecamers, as well as variable length helical arrangements and homo-oligomeric spirals. These proteins have roles in vitamin and co-enzyme metabolism, in detoxifying small molecules, in the synthesis of signaling molecules, and in the post-translational modification of proteins. They are used industrially, as biocatalysts in the fine chemical and pharmaceutical industry, in cyanide remediation, and in the treatment of toxic effluent. This superfamily has been classified previously in the literature, based on global and structure-based sequence analysis, into thirteen different enzyme classes (referred to as 1-13). This hierarchy includes those thirteen classes and a few additional subfamilies. A putative distant relative, the plasmid-borne TraB family, has not been included in the hierarchy.	2.68733e-36
NZ_CP009896.1\|WP_052139230.1\|1002667_1003870_+\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.37762e-99
NZ_CP009896.1\|WP_038677062.1\|1009166_1010000_+\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	5.06626e-58
NZ_CP009896.1\|WP_038677058.1\|1003872_1004649_+\|SDR-family-oxidoreductase	gnl\|CDD\|181113	PRK07775, PRK07775, SDR family oxidoreductase.	1.29698e-108
NZ_CP009896.1\|WP_038683519.1\|1006024_1006228_+\|ferredoxin	gnl\|CDD\|224064	COG1141, Fer, Ferredoxin [Energy production and conversion].	6.95303e-07
NZ_CP009896.1\|WP_082003547.1\|997573_999646_-\|hypothetical-protein	gnl\|CDD\|379868	pfam16656, Pur_ac_phosph_N, Purple acid Phosphatase, N-terminal domain. This domain is found at the N-terminus of Purple acid phosphatase proteins.	3.16795e-24
NZ_CP009896.1\|WP_038677060.1\|1006838_1008299_+\|aldehyde-dehydrogenase	gnl\|CDD\|275104	TIGR04284, aldehyde_dehydrogenase, aldehyde dehydrogenase, Rv0768 family. This family describes a branch of the aldehyde dehydrogenase (NAD) family (see pfam00171) that includes Rv0768 from Mycobacterium tuberculosis. All members of this family belong to species predicted to synthesize mycofactocin, suggesting that this enzyme or another upstream or downstream in the same pathway might be mycofactocin-dependent. However, the taxonomic range of this family is not nearly broad enough to make that relationship conclusive. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP009896.1\|WP_141267140.1\|1010474_1011167_+\|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl\|CDD\|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	8.87248e-14
NZ_CP009896.1\|WP_052138255.1\|1013794_1014442_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.18119e-14
NZ_CP009896.1\|WP_038677063.1\|1010001_1010391_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	3.33489e-13
NZ_CP009896.1\|WP_052138254.1\|1011534_1013550_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	1.10252e-05
NZ_CP009896.1\|WP_082003550.1\|1016694_1018071_+\|LCP-family-protein	gnl\|CDD\|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	3.04898e-47
NZ_CP009896.1\|WP_038677061.1\|1008423_1009170_+\|SDR-family-oxidoreductase	gnl\|CDD\|236094	PRK07774, PRK07774, SDR family oxidoreductase.	1.54523e-136
NZ_CP009896.1\|WP_038677052.1\|1001133_1001982_-\|LLM-class-F420-dependent-oxidoreductase	gnl\|CDD\|274680	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a domain found in a distinctive subset of bacterial luciferase homologs, found only in F420-biosynthesizing members of the Actinobacteria. [Unknown function, Enzymes of unknown specificity].	1.15346e-74
NZ_CP009896.1\|WP_038677054.1\|1002050_1002638_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.31562e-06

>NZ_CP009896.1|WP_038677060.1|1006838_1008299_+|aldehyde-dehydrogenase
MTALPPPAQQLIDGKLVAASSGATYPIVNPATGLEIGVAPDGTAEDVEAAIAAARRAFDESAWPTDLALRVRCLRQLHTALLEHADAFRALTTAEVGMPGFMMGAAGFDVPVDGLKWVTDLAETYAFEADLGVAAPMGIPSRRTVRREPVGVVAAITPWNVPTQINLAKVGPALAAGCTVVLKPAPDTPWVAAELGRLVAEHTDIPPGVLNVVTPRSNEVAAVLSTDPRVDMVSFTGSTGVGRAIMAAAAPTLKKVFLELGGKSAAIALDDADVAAVAGATAFAACIHAGQGCAITTRLIVPRDRYDEAVSVAAATMESIGAKDPADPGAICGPVISAVQRERVAAYFDVARAEGGTFATGGAVIDQPGFWVQPTVVSGLDSSSRLAQEEIFGPVLVVLPHDGDDDAVRIANDSAYGLSGSVDSASLERARAVAARIRTGTLAVNGGVWFSPDAPFGGYKQSGVGREMGVAGFEEYLETKTIAEPA
>NZ_CP009896.1|WP_052138252.1|1006227_1006842_+|hypothetical-protein
MSLTRAEIEEFWDSWLAVNREAERTGDWRVMADWYAEDASYGWMYSHDEHFMAMGRDQIRDWAIGIEMDGFDGWHYDYVCTVIDEQKSMIVGFWKQRSGILDDNGEEYEILGLGGSWFGVERQTAGPDAGQVKIAWQRDWFDMPSTAHTFLSIIQDGKASERLLERMSVTGHGVPGHYHRKDLPSTVWPPPVERGDYVTQEPVS
>NZ_CP009896.1|WP_038683519.1|1006024_1006228_+|ferredoxin
MSFRVVADTSICQGHQLCQGEAPDVFGFDDDADTVLLLEEHPDESRRDDVTTAVKYCPAFALSIEEN
>NZ_CP009896.1|WP_082003548.1|1004645_1006028_+|cytochrome-P450
MTLADIPEVSTVLDDQSPDVPAIIKGTGHLPEMRVDPIGLFDRVRAECGDVGRFRLADKDVVLVTGAEANEAFFRAPEDVLDQAAAYPFMTPIFGKGVVFDASPEERQQMLKNQALRGEQMRGHAQTIEAEIRRMVADWGAEGEIDLLDFFAELTIYTTSSCLIGKPFREELDSSFAHHYHELERGTDAIAYVDPYADIESFALRDAARVRLVALVQDIIDRRVSTGSTSDRRLVAKEERDLLDVLISIDMNADTITGIFISMMFAGHHTSSGTASWAMIELLRNPSVLSDVVSELDALYADGSEVSFQALRSIPVLEAALKETLRLHPPLIILMRLVQEDFELLGHTIPAGTLIAASPKVSNRIEADFPDAASFDPGRYIDPRQEDLQNRWTWIPFGAGKHRCVGNAFAMMQMKAIFSVVLRDFEFEMAQPAEDYRDDCSKMVIQLEQPCRVRYRRRSR
>NZ_CP009896.1|WP_038677058.1|1003872_1004649_+|SDR-family-oxidoreductase
MGKYDQPARRPAVVAGASSGIGAETARCLAAAGFPVALGARRVERCEEIAAEIRAAGGEAVAHPLDVASDESVATFAAKAAADLGDVEVVVSNAALIGPGALLETDSARLAAEVDVNLLGPHRLVRAFVPAMVARTRGDIVFVSSDVALRARPYMGGYSATKAGLEGLVASLQMELEGTGVRASVVRPGPTWSEMGMDWEPDAAAKVLNEWMKWGHARHSHFLKASAIADVITSVVSAPRGVHLSPVDVNPEAPVESS
>NZ_CP009896.1|WP_052139230.1|1002667_1003870_+|cytochrome-P450
MSFDPYDYAFQDDPYPTYQRLRDEAPVHHAAADDLWVVSRHADVFAVLRDDETFSNRMGVSLDASAWSPDAHRVMSFLALDGAEQSRIRRLVSAAFTPRRVRELAPEVQALTERYLASTLERSADSDADWIRDLAGKLPMDVISEMMGVPVPDRDEVRRLADLVVHREDGVRDVPQAGMEASIELMTYYAAMVKERRAAPSDDLTSALVAAEVDGDRLRDGEIMAFLFLMVVAGNETTTKLLGNALFHLSAHPEQRAQVLADPDLVGPWIEETLRHDTSSQMLARHVERATEVGGVAVPAGAKMLVLLGSANRDERVFTDPTSYDVHRDKAELAQILSFGTGRHFCLGANLARLEARIVLEELVRRVADLEVHADRAVRVHSTSVRGFASLPVTFSVRSS
>NZ_CP009896.1|WP_038677054.1|1002050_1002638_+|TetR/AcrR-family-transcriptional-regulator
MSSQVFETPRQGLNRRQAETVERLLTAGLAELRAVGHEALTIRTVAQRAGVSPATAYTYLASKNHLFAELFWRHLNAAHLRVSTDGTAVERLQATMRALTARIVEEPELAAAVTPALLGTDPDVARLRLKIGGEFLARFEAALREPRRPADPAVLDVLVLTFSGALLQAGMGLLTYDQIAERLVSAVDVILRGNP
>NZ_CP009896.1|WP_038677052.1|1001133_1001982_-|LLM-class-F420-dependent-oxidoreductase
MRNGIVLFTSDRGITPARLAQAAEERGFDTIYVPEHTHIPVRRDALHPTGGEDLPDDRYLRTLDPWVSLATCAAVTERIGLSTAVALPVESDPITLAKTLATLDHLSGGRLTVGAGFGWNTDELTDHHVPAAKRRTVLAEYLGAMRALWTEEEASYDGEFVSFGPSWAYPKPPQGRIPVIIGAGAGPKTMKWIAAHADGWMTTPTSTDVAAGAELLRKEWADAGREGEPDVRVLVAKRPAAEDFADWGAAGASELIWGVPDSDESAVLTYLDKLAGRLGLSA
>NZ_CP009896.1|WP_038677050.1|999892_1001137_-|hypothetical-protein
MTSRYAALSRAELATLVPELLLMGQLIDRSGMAWCIAAFGRDEMLQVAIEEWAAASPIYTRRMQDALGYAPAVAGQGDVVTIFKGLQLDIGAPPQFMDFRYTVHDAWHGEFRLDHCGALMDVEPMGEDYVRGMCHDIEDPTFDATAIATNPHAQVRPIHRPPRTPADRHPHCAWTVTIDPAFPEPEPVPALAVNAGSRAATLALDPIDPADEGVADYTGPLLSDVDFAAFSHSALVRIADEVCLQMHLLDRAFALAVAERVETDAELVKLRRKQLVGIAGIGAERLARALDLPRDPAGALRAMWLHPLLNPAAYVSAGLLPDEIAVTPGPADEDGAWISLCGPDWPEALRAIAHAVAPELDARITAAPGAGGGWRVQVVEGEARPEADEVAVTRFSTGATFAFAPRRSLPLTVA
>NZ_CP009896.1|WP_082003547.1|997573_999646_-|hypothetical-protein
MTPTSRQHRSRWRRRPAVVAGGLALSLAAGAGLVWAAGGGLAPPAVDPKVVHAPLVVPDRIVLTPTTDPATSQSVSWRTSAAVTTPKVQLTLAGTGVAKPSSTVDATSTTFTADLGYDVRQHSATLTGLQPGTTYLYRVGDGETWSEWLEFETARTGNAPFSFIVQGDAQNDIKSYVSRTFRAAYEARPYAKAVLHAGDLIDTDDSDAEWGEWFGAAGWSNGSMNVIAAAGNHEYYPGPELAEHWGAQFEYPRNGPETTSRIAQLYSENVYYTDYQGVRFIALNSNFPGDPEAFAAQTAWLEEALKNNPSKWTVVTFHHPVFSVSSGRNNAAIRDAWLPLFEKYDVDLVAQGHDHAYGRGNLVANESGLPAGASADRSNKGPVYMVSVAGPKYYVIDPVGDNNWTQNGAHLRTSLANTQLYQLVDVTDGEMHVESWNVSGQMVDAFTIAKGADGTKLVTTDTTPRASGPGSTRGGIGRPGLPEPAVPGEKPTEPETPTKVVPVVRATTSQQRYGTTAPVRVSATIAPVAGAVPPGTVTFRTGSRVLATGVRVTDGTAALTLPRDLAVGSYAITAQFVPTGTGFETGTSTATTVRVVKASSTVTISGLPAKVKAKARRTLAIRVAVPGIAAPAATVTVRVDGRVVATRTVTGTVSIKLPKLRPGKHKVTVDYAGTANVAASRVVKKVVSRR
>NZ_CP009896.1|WP_038677061.1|1008423_1009170_+|SDR-family-oxidoreductase
MRFENKVVVVTGAAQGIGEAYAKALAAEGAAVVVADVNAEAGEQVAKQIEADGGQALFVRCDVSSAESAQALVAATVERFGGIDGLVNNAAIYGSMEFDLLISVDWDYYRRFMSVNMDGALVMTRAVYPELQKRGGGAIVNQSSTAAYLYSGFYGLAKVGVNGLTQQLAHELGGMRIRVNAIAPGPTDTEATRVQAGDAAKELVKNLALKRMGSVDDMVGACLFLLSDDAGWVTGQILAVDGGQTFRA
>NZ_CP009896.1|WP_038677062.1|1009166_1010000_+|NAD(P)-dependent-oxidoreductase
MSAPLRAGFVGLGNIGKPMALRLAAADGVDLHVHDVAPEPVAELVAAGATAAGSVAALAAAVDVLFVMVRDDEQVRAVAEEAGPGTVVVVHSTVAPGTPAALEAAGLTVLDAPVSGGPMGAADGSLAIMVGGDDEAFAAARPVLEAMGAKVVHAGPVGAGTRMKLARNLIHFVAFTAVTEAQRLAEVAGLDLVALGDVVRHTDAITGGPGAIMHRPTTAPLAADDFWHGVFTHVAALGEKDLGFAIALADGLGVDVPLARLAHDRLGPGLGLTRGDR
>NZ_CP009896.1|WP_038677063.1|1010001_1010391_+|carboxymuconolactone-decarboxylase-family-protein
MGKFDDLPETRRRGLEKMEQVYGFDMTDGSGDFFRYTADHLFAEIWERPGLTDRDRRLLLIGMLAGQGAADVLGIQVPAAHAAGELDDEALREIVVFLSHYAGWPQGARLNSIVEETIAKARRHRGDAG
>NZ_CP009896.1|WP_141267140.1|1010474_1011167_+|4'-phosphopantetheinyl-transferase-superfamily-protein
MTLESLLAVPGGTADDDARLGVWSIATEGVGDDELEVGRSWLDAGEREQASSYVRAELRRAYEIAHAAARLVVGAATGAEPQDVVWGRHACPGCGEPHGRPRAEGAAVEFSLSHTPGQVLVAVADVPVGVDVERHPDDPVALAKLLHPRETEEIEAAAHGTLDGGRATVRFTRAWARTEAYLKGLGIGLGRDPHLDYLGTDQAAGRRLGEWSVRDVTVPEGYGAALALLR
>NZ_CP009896.1|WP_052138254.1|1011534_1013550_+|LPXTG-cell-wall-anchor-domain-containing-protein
MVLASTAFAAPALADDVDSDPGTPAVSETPAPTPDPKPAPEPKPAPKPTNEPDQGGSGSSSDDKPAGKPDKPTGATSTDDAEPATPAAPVEAPKTPAKKAAAVATPSAGTLFSAAAAEDEPNEKKVVVCKYVSTPPGVLHHIVIPSVNSLPGFPGTFPWAFADAQISVAIRYANVGEQAHDVSLSECPTQIAKPVVPVTDECGPGNAVYGEIPVGNYTAVRNPDGSITLTADAGYLFFGGTKTVTLPVPVETNTAACPEPAEIAPPELDVIDECGPGNAHYEPVPASDDYTSVVNQDGSVTLTAVAPATFPGGAATYTYPVPTETNTAACPVNEKKVVVCKYVSTPGGVLDHIIIVSVNTLKDFPDPAVFPWQFPDAQDSVAIRYALDGEQAHDVSDVECPQAITPPEVPVTDDCGPGNAVYGEVPAGHYSVTRNQDGSITLTADAGWTFPGGAPTYSYPVPEDQNVACPAAITPPELDVTDPCGPGNAVYGEVPENQGYTVTRNEDGSITLTAVGNTEFPGGAPTYTYPVPTETNTEACPVDGRAVVCSIPMSTQVSARADIPGTILILDIADLIAKGFAGVFPFSYTENGVEYDVIRAAAPGETADQVTGITCGVDDVVVNHPPKTPGEVGGVTTGLPNTGGPAGWLIPAGVAMVLAGAALMLLRRREA
>NZ_CP009896.1|WP_052138255.1|1013794_1014442_+|TetR/AcrR-family-transcriptional-regulator
MTTSPRGARRKARTATAILDAAEGLFRERGLQATTIDEVAEAADVSVGSVYVHFKSKTGLYLALVERALDLNEQAMARVLDLGLDSPLERVLAAGDAYLRFHLEHPGAFQMIALRVLEPGSGQSDPEVEERIAERVEALVGAVQADLEAAVRAGEIRADVDLARATRFVWGAWNGVIALSLRQDRLRIDDDELAATLAVGRRLLSDALRADAAGQ
>NZ_CP009896.1|WP_038677066.1|1014404_1014815_-|hypothetical-protein
MSTTPSPLTTSGAVEIAASALSGWVYTLAIADKERARRLGIVSTPRVRQWHLDLAALGTATVALGAALPDAPAPLRRTLAAGSWTNAMLFLPLAFRPGLADDRRYRVAVAGSFVTTSVGFVGFAATALRRRRAARR
>NZ_CP009896.1|WP_038677067.1|1014811_1015765_-|carbon-nitrogen-hydrolase-family-protein
MSTTPTTIRAAAVQTEARLGDVDANLADCARLADQAVRAGATWVVLPEFFSTGIGYLPELSARAPSIDGEPTRLLAGLATRHGIHVGGSTLVRDPDGEVRNAFLLFGPDGLAGRHDKDLPTMWESALYTGGRDPGRLDVAGTTVGVALCWELMRSQTVARLGGEVDLVVGGSGWWSLPEWPLLGGAERRNHARATAAPATFARYVGAPVVHAAHAGRVACDFLGTPLRYRGRLEGGAQICDARGRVLAYRDRDQGAGVVLADVTLGRATPTFASDRFWLQRRGAVAATAWHFHNAVGRRAYARAQQRRHHRPEESTR
>NZ_CP009896.1|WP_141267139.1|1015971_1016385_-|hypothetical-protein
MTTRRSGLRNAALLLAFSALAAGCAGSDEEATVEGATVLIATGALEGESDVMVSGVVAKIGDCLGIKVEQTTYPLIWPKHVEIEDARVSLDGTSFGLGDELSGGGAFLPEPYPSQAPDIPEGCRSATGEIVLLSQLK
>NZ_CP009896.1|WP_082003550.1|1016694_1018071_+|LCP-family-protein
MTQDVETSRAAGEPSAPGSRARRVPTSRASRASRDVRRPRGRRSGGGRRKAPQPGKTVFKVIAASLLSLAMATGVGVVLVYNNWNGNLKREDVSKLLSNRPTKEKVAGPSEPLNILVMGSDTRAGEGNGIDGEAGGGLSDTTILFHVSANREFAYGISIPRDTAVMRPECRRKGGAVVPAASGYEKWNAAYALGGPSCTIQQFEQLSKIRVDKYVVLDFNHFKDMVNALGGVEVCIPEDIDDNEHNIHLKAGTREIKGAEALTYVRVRYRVGDGTDTQRTRRQQAFIGSMINKALSADMLARPDHLIGFLNAATASLQTDFKTVAQMADLAVTARGIGADNIKFVTTPWAYSDKVSGGIEWTPEVLKLWQLVRKDKPLTPEFLKDALSAGDKPDGTASATGTASGTPGGTGTGTATDGPSGTPSGTPGGTASNGQPGQNPTQDGGLSTSGREQAGLCT

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_4

1089965-1090055

Orphan

Consensus_repeat	Method
GTTTCACCGCCTAGGCGGTGAAACTGCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_4

>merge|NZ_CP009896|4|1089965-1090055|CRISPRCasFinder
GTTTCACCGCCTAGGCGGTGAAACTGCCGGTTGGCGCATGGAATTCGCTGTGCCCAGGTCCGGTTTCACCGCCTAGGCGGTGAAACTGCCG

>NZ_CP009896|4|4|1089965-1090055|CRISPRCasFinder
GTTTCACCGCCTAGGCGGTGAAACTGCCG	GTTGGCGCATGGAATTCGCTGTGCCCAGGTCCG
GTTTCACCGCCTAGGCGGTGAAACTGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038677129.1\|1087314_1088631_+\|flagellar-hook-associated-protein-FlgK	unknown	unknown	gnl\|CDD\|236084
NZ_CP009896.1\|WP_141267127.1\|1093007_1094252_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038677130.1\|1088644_1089535_+\|flagellar-hook-associated-protein-3	unknown	unknown	gnl\|CDD\|181087
NZ_CP009896.1\|WP_075018745.1\|1085785_1086598_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274153
NZ_CP009896.1\|WP_038677126.1\|1083421_1084759_-\|flagellar-filament-capping-protein-FliD	unknown	unknown	gnl\|CDD\|224264
NZ_CP009896.1\|WP_038677124.1\|1082694_1083021_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_075018733.1\|1092270_1093011_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213231
NZ_CP009896.1\|WP_141267135.1\|1099967_1100699_-\|response-regulator	unknown	unknown	gnl\|CDD\|225107
NZ_CP009896.1\|WP_038677123.1\|1080897_1082679_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038677133.1\|1091716_1092268_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_082003554.1\|1090158_1091307_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_CP009896.1\|WP_038677135.1\|1094236_1094875_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038677136.1\|1094957_1097123_+\|chemotaxis-protein-CheA	unknown	unknown	gnl\|CDD\|223716
NZ_CP009896.1\|WP_038677127.1\|1084868_1085666_-\|flagellin	unknown	unknown	gnl\|CDD\|183759
NZ_CP009896.1\|WP_038677132.1\|1091316_1091580_+\|carbon-storage-regulator-CsrA	unknown	unknown	gnl\|CDD\|376847
NZ_CP009896.1\|WP_038677131.1\|1089531_1089933_+\|flagellar-assembly-protein-FliW	unknown	unknown	gnl\|CDD\|376865
NZ_CP009896.1\|WP_038677137.1\|1097119_1097587_+\|chemotaxis-protein-CheW	unknown	unknown	gnl\|CDD\|238374
NZ_CP009896.1\|WP_038677128.1\|1086835_1087315_+\|flagellar-protein-FlgN	unknown	unknown	gnl\|CDD\|377465
NZ_CP009896.1\|WP_082003915.1\|1097694_1099869_+\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP009896.1\|WP_038677125.1\|1083017_1083410_-\|flagellar-export-chaperone-FliS	unknown	unknown	gnl\|CDD\|376819

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038677129.1\|1087314_1088631_+\|flagellar-hook-associated-protein-FlgK	gnl\|CDD\|236084	PRK07739, flgK, flagellar hook-associated protein FlgK; Validated.	1.04648e-82
NZ_CP009896.1\|WP_038677130.1\|1088644_1089535_+\|flagellar-hook-associated-protein-3	gnl\|CDD\|181087	PRK07701, flgL, flagellar hook-associated protein FlgL; Validated.	1.7029e-75
NZ_CP009896.1\|WP_075018745.1\|1085785_1086598_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274153	TIGR02479, RNA_polymerase_sigma_factor_WhiG, RNA polymerase sigma factor, FliA/WhiG family. Most members of this family are the flagellar operon sigma factor FliA, controlling transcription of bacterial flagellar genes by RNA polymerase. An exception is the sigma factor WhiG in the genus Streptomyces, involved in the production of sporulating aerial mycelium.	2.07336e-59
NZ_CP009896.1\|WP_038677126.1\|1083421_1084759_-\|flagellar-filament-capping-protein-FliD	gnl\|CDD\|224264	COG1345, FliD, Flagellar capping protein [Cell motility and secretion].	2.03332e-43
NZ_CP009896.1\|WP_038677136.1\|1094957_1097123_+\|chemotaxis-protein-CheA	gnl\|CDD\|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	6.71531e-157
NZ_CP009896.1\|WP_141267135.1\|1099967_1100699_-\|response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.22997e-59
NZ_CP009896.1\|WP_075018733.1\|1092270_1093011_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213231	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	9.23351e-65
NZ_CP009896.1\|WP_082003554.1\|1090158_1091307_+\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.59965e-39
NZ_CP009896.1\|WP_038677127.1\|1084868_1085666_-\|flagellin	gnl\|CDD\|183759	PRK12804, PRK12804, flagellin; Provisional.	5.5142e-72
NZ_CP009896.1\|WP_038677132.1\|1091316_1091580_+\|carbon-storage-regulator-CsrA	gnl\|CDD\|376847	pfam02599, CsrA, Global regulator protein family. This is a family of global regulator proteins. This protein is a RNA-binding protein and a global regulator of carbohydrate metabolism genes facilitating mRNA decay. In E. coli CsrA binds the CsrB RNA molecule to form the Csr regulatory system which has a strong negative regulatory effect on glycogen biosynthesis, glyconeogenesis and glycogen catabolism and a positive regulatory effect on glycolysis. In other bacteria such as Erwinia caratovara RmsA has been shown to regulate the production of virulence determinants, such extracellular enzymes. RmsA binds to RmsB regulatory RNA.	2.44573e-22
NZ_CP009896.1\|WP_038677131.1\|1089531_1089933_+\|flagellar-assembly-protein-FliW	gnl\|CDD\|376865	pfam02623, FliW, FliW protein. The protein BSU35380 from Bacillus subtilis (renamed FliW) was characterized as being a flagellar assembly factor. Experimental characterization was also carried out in Treponema pallidum (TP0658). In Campylobacter jejuni, Cj1075 has been shown to be involved in motility and flagellin biosynthesis. The two paralogues in Helicobacter pylori (HP1154 and HP1377) were found to be able to bind to flagellin. FliW proteins are involved in flagellar assembly. FliW is part of a three-part feedback loop: in Bacillus subtilis FliW inhibits CsrA (an RNA-binding protein) which inhibits FliC translation; hence FliW is required for FliC (flagellin) production.	2.33988e-35
NZ_CP009896.1\|WP_038677137.1\|1097119_1097587_+\|chemotaxis-protein-CheW	gnl\|CDD\|238374	cd00732, CheW, CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together with CheA and the methyl-accepting chemotaxis proteins (MCPs), which are involved in response modulation.	1.53609e-28
NZ_CP009896.1\|WP_038677128.1\|1086835_1087315_+\|flagellar-protein-FlgN	gnl\|CDD\|377465	pfam05130, FlgN, FlgN protein. This family includes the FlgN protein and export chaperone involved in flagellar synthesis.	1.44026e-08
NZ_CP009896.1\|WP_082003915.1\|1097694_1099869_+\|GAF-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.97972e-54
NZ_CP009896.1\|WP_038677125.1\|1083017_1083410_-\|flagellar-export-chaperone-FliS	gnl\|CDD\|376819	pfam02561, FliS, Flagellar protein FliS. FliS is coded for by the FliD operon and is transcribed in conjunction with FliD and FliT, however this protein has no known function.	1.53433e-30

>NZ_CP009896.1|WP_038677131.1|1089531_1089933_+|flagellar-assembly-protein-FliW
MIEAMDIPVIELAHPMPGFPADERFALVRLDDTGVLHGFRSLDSDDLQFVVVPPAPFYPDYAPEIADDVADELGISSDSADDVLVLLVVRAGATLADTTVNLRAPLVVNPATRRASQVILDDVALPLAAPLVA
>NZ_CP009896.1|WP_038677130.1|1088644_1089535_+|flagellar-hook-associated-protein-3
MSIGRVTQRMLTEGSLGHLQQGLGRLARLQEQLSTGKVINRPSDNPTGTTAAMRMRGSMADQTQYSRNAQDGLGWLTQIDSALDSVTTTVRRARDLALQGANASASGQVARDAIATEVEGLRKELLSRANTTYLDSPVFGGVTAGRTAYDASGNYVGTVGDVNRRIAEGVVVKVDLDGPVVFGDGATSVFAELDALATALRAGDQAGISNAITTLNTRMETVTAARTAAGTRYQRLEQADQAAGDAKISLEKQLSTVENADLAETTVALKLQEVAYQAALGATSRVLQPSLLDFLR
>NZ_CP009896.1|WP_038677129.1|1087314_1088631_+|flagellar-hook-associated-protein-FlgK
MAGSFGSISTALSGLRYNQVLLDVAGNNISNADTDGYVRRRVVGSSVSSAAPALWSRYDGHGEGVSVGEVRRMVDPLLDARVRREHGMLAYLQTTSTVLSRVEEGIGEPGANGVHAAMLDFRNAWQDLATNPGGAAARQQVLGRAETLAQALRVQVSNIAGEEADQQVHLTSLVSEVNTAATDLAALNRSILVTEANGTDAGTLRDRRDQLALRLSELTGATTTVRPDGQFDVSVAGASLVSADVASTFAIDPAATYGGAIGAVTTLLTTTLPAYRAGLDAVAADLANAVNSQHALGFDANGNPGGTFFTFDPAVGAASLQVAITDPNLVAASSLGGTARNGDNADALSRVGTYSDAYQKLVNGFGTQVAAVGRQTANQAALTGSLDTAWEQQAGVNLDEETVTMLTAQRAYEAAARLLTTLDEVLDTLINRTGIVGR
>NZ_CP009896.1|WP_038677128.1|1086835_1087315_+|flagellar-protein-FlgN
MDRLSQILWRERELLELLAYKLEVERLVLASGRTRWLVNATREIESLLEDLRATEVLRATAADEVAEKLGLTPNPSLAALAEASDDPWRGILLDHRDALVGVAREIAETSEDARGLITAGYRSARETLLAIGGTSTASYTPAGAAVADAPRSHLLDRSL
>NZ_CP009896.1|WP_075018745.1|1085785_1086598_-|sigma-70-family-RNA-polymerase-sigma-factor
MDELITTHMPLVGHIVRETMGRVPSHVSRDDLTSAGLTALVLAAKAYDESRGVPFDRYAATRIRGALLDELRSVDWASRSVRRRARDLAETRNRLATVLGHTPSVAEVARAAGLSEDEVAANDDDVSRAQVLSLQGSSATPIEELVATRAPSPEELVEHAERLTYLREAIEELPERLRVVVQDYFFSERPMADIAADLGVTDSRISQMRAEALTLLRDALNHALEPSLVKQNGKAGGVAQRRRESYFAAVAARHAQSARGGVVRPLDAVG
>NZ_CP009896.1|WP_038677127.1|1084868_1085666_-|flagellin
MGLRINQNIEATNAYRNLSVTQNQLSKSMEKLSSGFRINRAADDAAGLAISEGLRSQVGGLKVAVRNAQDGISVAQTAEGALTEVHSMLQRINDLAVQYNNGTQNTDSQAAIEAEVTELNAEITRIKDNTKFNGVSLFGGTALDFQVGYADADTITVSATALADFTTAVGTLTAAGGSDAVQAAITAVSTQRAELGAVQNRFEHTINNVNVAIENLSASESRIRDTDMAQEMMSLTRSQILSQAGTAMLAQANSAPNGVLQLLRG
>NZ_CP009896.1|WP_038677126.1|1083421_1084759_-|flagellar-filament-capping-protein-FliD
MAATSSIGGLASGLNTADIINQLIALEALPQTKLKTQVTTEQSRITALQKVNTALQALMASAKTMQSTTTGPWATLASTSSNAAVSVTATSTASPASFTVTVGQTALSHQVAFTDAHAKSDAVTGATNGVLLKRAGQPDLAISTANGTLEELAAAINSADAGVRATLVRTGTAGGTDQYRLLVESATTGAAGAFELTDSTGAPLLGGTTVRAGRDATIEIGGITATSASNTFTDVVPGITITLGATATGTAEVAVSRDAASRSASVKSMVDEANALITQISGLTLNSLTTKGVLAGDSTLRDVASALAETIYPGDGTSMASYGIQVDRFGKITFDTQKFADAYAADPAATAAVFTGPDGFAARLQKAADAASDKYDGTVTQSITSRNVTVTRLNDSIERWDTRLELRRATLERQYTALEKALSQLQGQSSWLTSQLNAFNANSNQ
>NZ_CP009896.1|WP_038677125.1|1083017_1083410_-|flagellar-export-chaperone-FliS
MYATPTVRNAQSAYRDNAVATASPARLLVMLVERLVLDVERGLAAQRAEDWPQAHHHLMHAQDVVVELESSLDVSAMTGGRELAALYEYLRTRLVVANVRRRTATTEEALGLARQLCETWREAAMTAAAR
>NZ_CP009896.1|WP_038677124.1|1082694_1083021_-|hypothetical-protein
MTGPEIPERPASWTEALDRLEAHADRAEHLLRGESAEPAPAPWQPPAELGPLPNELVPRARQLLARQQRLMAAIPAVLSDKRQQQRIADRVGDATTAAVTPIYLDVTA
>NZ_CP009896.1|WP_038677123.1|1080897_1082679_+|hypothetical-protein
MSEHRAHRRARRVRTRLLSAGLLLAGAALVATAASPPPALAAGQAISTTTNVTASTGNGACLRPSTPADPVNCNAYGVKDDVWLSNLPSALGDGEYFVAVTAPGGQADPNDGSASLLSAGTHLDRAFSIVNGVVSPLGDHVVENQRVQLAPFADTPNAGGVYIATVCRLADYPASGSSCTHDAFKVGASDPAVPDPLTVVKDAAGDYTRTYAWTIAKTADPAEVHGTSGSVNVGYTVTVGHDEGTVSGVEVSGTITVLNPNADPVVADVTDQLSDGTPCAVTGGAGALMAPGDSTFAYHCTLASLPQAQLDNTVTVTWADQAVGTGQLAAGSGDFVFDAVPFVPSVVDDCVAVDDTAVGALGQVCVGDANPSVLTYGRTFPLTTPGCVVHPNTAGFTSDDSGSTGSASADVKVCKDPLATGAHTIGFWSNKNGQGVITGSAGTSSSCVAGTYLRTFAPFQDLAANAKCADVAKYVAAVIAKATGSTMNAMLKAQMLATALDVHFTGPGSTTATRKFLPSSNLGATVVDLTTIKGRDVRGAFGGATSLTVSQALAYAAGRSNVGGSTWYANVKSTQTDAKDAFDAINNQVAYAP
>NZ_CP009896.1|WP_082003554.1|1090158_1091307_+|MFS-transporter
MALAAALGTSTIYPLQPAIADVAAALDSSVAAVGLALACGSVGYLAGLGLVVPLVDHLAPGRVLAVQLAVLALALGAGALVGHVVVLAVVTGVVGACSTVGAGLSSVAGRFAPPHRRAAVLGTVTAGISAGILAGRIAGGWLADELGWRAMLLVLAGACALTALACSALLPGGRGTADRGYVATVRSLPGLLVAHVRLRRAALRGALWFFAFCAVWSGLAVALSAPPYSYSAERIGLYALAGLSGILATRVAGTSTDRVGARPVVRTGLALAALATVALAFGLASTVLTLACLAVFDAGLFAAQVANQSTVLALDPTAPARFNSAYMVVYFVGGSLGTGFGAVAVEHVGWEANVLVAAVAIATAASIAVPEPVAATTEIPAR
>NZ_CP009896.1|WP_038677132.1|1091316_1091580_+|carbon-storage-regulator-CsrA
MLVLSRRVGESVVIGGGSPEAVTVTVLEVRGDVVRIGIDAPRSVAVHRAELLAELADANADAASPSESAVASLSQALRGSGTDSGTD
>NZ_CP009896.1|WP_038677133.1|1091716_1092268_+|hypothetical-protein
MSASTSLPARFRAGALLVLVPLVASIAVVLVLGPPADAKVRKWNSLETPLTAFDNGKAKASGYGTWQIGTTVNGTRSQAYGYLRDRDTTNDNAVYFELFTQTNAGTCLAPEYTSCSASYFTYASQFSDFDKETWRKGTWSPRFYASTALNPSGSYARALMQVSESNSGPDTHSKNTFTKGNPY
>NZ_CP009896.1|WP_075018733.1|1092270_1093011_+|ATP-binding-cassette-domain-containing-protein
MGEVRCVGVEVARGAFRLGPVDLVIGPGVTVLVGRNGAGKTTLLRAVVGLVPTAAGTIEIGGSAQGERRARAGLMRRIGYVPQGAEVPGGARVVDLLRYAAWLKDVPRPEAEARVAEALDELDVAHLATRRARTLSGGERQRVSIAMSLVHRPVLLVLDEPSVGLDPVQRVALRGLVDRLGRTRAVVVSTHVVADIDEHDDTVVVLDAGTVTFTGSADGVAARARPGDHGASDLERGLWRLLGSGG
>NZ_CP009896.1|WP_141267127.1|1093007_1094252_+|hypothetical-protein
MSRGSRARYLLGTSRATLAVVPMLVAVGYAVLPSLTLWRGDWWWGFNHALQAVPVGVVLTAFVAGWDAGAPGSGHRALRDRAPVAGWRTHATLLLPPFAAAAVPYLLGVLVVAVATVTSDGVVDPTAGLVVLAHLSMFALAATVGVAAGGVVSSPYAAVAATAVLGALLFWSVPGGWSLFAFPGTAGPAVEQAAMSSRYGVTVLGLLLAAVCLTAPALPLAARRVTVAGGVAAAVGALWVSSLVVSPDLYVSSGERPTRCRTSSITVCVYPGYDRLLRPAADSLERALDVAATHGVPRANFPARYEQGGNLRSPEGVGELVVGTRSLRDRTLDADAVVQSLTTPLWCAEMFANLPPLPLLGRRDLVADWLYLIGGALPQEEFLVWHPEQQGRRPDQVAAAVRTALAEIRTCTNT
>NZ_CP009896.1|WP_038677135.1|1094236_1094875_+|hypothetical-protein
MHQHLTTRRSRVPETFRVVGFHLRLRPWTALCLAGCLAVLLLSAGHTVPSLQDDVRVPRPRASLPVGCAVASLVVLLVRPVLDGAERLAARDLRAARLVLLVVVVGGAGGAAGALTPLLAVPAVGVRCLTLAGALVGIGLVAGVAGLFWGLAVPWLYVLSGLAFGYGSTMEHGTLTVRPWAWLVAEQVPAGAELAVLAGGVLVAAAVRPRGT
>NZ_CP009896.1|WP_038677136.1|1094957_1097123_+|chemotaxis-protein-CheA
MDDDAEIIAEFLVESHENLDQLDRDLVELERQPDSRERLSSIFRTIHTIKGTSGFLAFNRLEALTHVGETLLSRLRDGETEMTPPIAEALLSMVDTVRALLGAIEQSGTDVDPAVAVDPVVAVLEGLLAEPAPPVETPEPPVETPEPLAETPVPPVEPVETPEPEPVETSEPERRTVVDASVRVDVDLLDDLVDLVGELVLTRNQLLQRSLGSADVELVRASQRLDLVASELQESVMKTRMQPIGQVWSKLPRVVRDLSHQLGREVELVMEGHETELDRSLLEAVKDPLTHLVRNSLDHGIEPPDVRRAAGKPGKGTLSLRAYHESGQVVVEIADDGKGIDPARIGAIAVERGVITRDQLARMEQREVLGLIFRPGFSTAAAVSNISGRGVGMDVVRTNIERIGGSVDVASEPGRGTTTRVRIPLTLAIIPALVVGEGGERYAIPQANLVELVRIEGDDVRRQVERLAGAAVLRLRGKLLPLVSLAETLGGAQPAPDEALTVVVLQSDDVRFGLCVSEVHDTQEIVVKPIGRQLKGLATYAGATIMGDGRVALILDVAGIASTAGVSAVPDEAADVRASAGDDRQALLVLEVADGRRAALPLAAVARLEEFAQDRVERSGTAEVVQYRDGILPLVRLAAAIGLPDTSDRGEQISVVVHETSDAAAGAVGIVIDRVLDVVEVAVTASQVGRRSGVSGSAVVQDRVTDLVDLAAVVARSGVSA
>NZ_CP009896.1|WP_038677137.1|1097119_1097587_+|chemotaxis-protein-CheW
MSTSTSTEQLCTFWVADLLFGVAVEEVQEVIRHQPMTPVPRADEAVRGLINLRGQIVTAVDLRVRLGLPPRDAEQLPMNVIVRSRGEVVSLLVDDIGDVIDTAGVDPQPAPSNLPRGVQDVVRGVRPLPDAILLVLDADRAVDVVTAPDTPGGNP
>NZ_CP009896.1|WP_082003915.1|1097694_1099869_+|GAF-domain-containing-protein
MEAGAFVVAPDYTIRFVNSRARREMAAGGPDIPQIDPDTLIGMSFEVIYAHPDHGAAITATPARLPLSDQVTGESTIHDVLLSAIHDASGTYVGALVTFEDVTLKVQAQREMAIATSMMENSPTNMMFADRDFVIRYMNPASLETLRGLEQHLPVRADEVVGSSLDVFHKSPAYQRGLLASADHLPRRADIQVGPETLDLLVSAIRDSSGEYVGAMATWDVITDRLRVERERAESAADTSAVNKILATLGSATDVEAAVQSTLDTLRGEFGWAYGSYWKVDPADRLLKFDRESGDAGPEFRRVTMQASFAEGIGLSGRAWAQRDLYFTRDIGEMTDCVRAPVAQQVGVKSGVCFPVIVDGDVVGTMDFFATETLEPSPQRLEALRNVGRLVSQAIGRIERETRERAEAAVLTGKVQQMLDVVSAAADGDLTRSLDIEGDDEVGRVAAGLRALLGTLRTSMGNIGGTAESLAAAADQLTSLSEGMGEGATTTSDRAASASSASVQVSASIQTVATAAEEMTASIREIAKNATEAATVATDAVTVASEAQGTVASLGESSAEIGQVIKVITSIAQQTNLLALNATIEAARAGDAGKGFAVVANEVKELAKETARATEEIGQKIEAIQSDTQGAVSAISRIADVIARINDIQSTIASAVEEQTATTNEIARSVTEAAAGANGIAEDVTQVATAAADTRVGAEQTLTSATELTGMAGELREMVGRFTL
>NZ_CP009896.1|WP_141267135.1|1099967_1100699_-|response-regulator
MRVYIVDDHEVVRRGVASLLATDPELEVVGQSGSAGVALREILELRPDVAVLDANLADGTGVDVCREMRAVDPEIKGLILTTYDDPDAISAAILAGASGYVLKKIEGNSLLNGIKLVAGGHSLIDPAVASRVVEQMEMQRRSLDVVCELTPQQRKIFFLIAEGMTNRQIAEQLYLAEKTVKNHVTGLLSRLGLQHRTQAALLAVRLRGAESATVAAPAVPAVPAAPAGPAGVAAGYGAERRVG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_5

1362631-1362741

Orphan

Consensus_repeat	Method
AGTTTCGCCGGTCGACCGGCGAAACTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_5

>merge|NZ_CP009896|5|1362631-1362741|CRISPRCasFinder
AGTTTCGCCGGTCGACCGGCGAAACTGGCGGACTTGTCGTACAAAACTCACGCTTGACCGACGATGCTTCAGCGGTCAAGTGTGAGTTTCGCCGGTCGACCGGCGAAACTG

>NZ_CP009896|5|5|1362631-1362741|CRISPRCasFinder
AGTTTCGCCGGTCGACCGGCGAAACTG	GCGGACTTGTCGTACAAAACTCACGCTTGACCGACGATGCTTCAGCGGTCAAGTGTG
AGTTTCGCCGGTCGACCGGCGAAACTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038677371.1\|1369865_1371464_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP009896.1\|WP_038677373.1\|1372285_1372777_+\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NZ_CP009896.1\|WP_052139242.1\|1358856_1359978_+\|phosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|270703
NZ_CP009896.1\|WP_038677365.1\|1358148_1358724_-\|TetR/AcrR-family-transcriptional-regulator-C-terminal-ligand-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|379883
NZ_CP009896.1\|WP_038677376.1\|1374643_1375762_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP009896.1\|WP_052138318.1\|1359974_1361159_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038677369.1\|1364474_1366187_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NZ_CP009896.1\|WP_038677362.1\|1355048_1355879_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_052138317.1\|1353047_1354556_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|376340
NZ_CP009896.1\|WP_038677363.1\|1355923_1357030_+\|GuaB3-family-IMP-dehydrogenase-related-protein	unknown	unknown	gnl\|CDD\|236322
NZ_CP009896.1\|WP_038677361.1\|1354555_1355059_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP009896.1\|WP_038677370.1\|1366474_1369765_-\|InlB-B-repeat-containing-protein	unknown	unknown	gnl\|CDD\|380193
NZ_CP009896.1\|WP_075018725.1\|1372906_1373290_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|225039
NZ_CP009896.1\|WP_141267112.1\|1373345_1373735_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038683694.1\|1357049_1357754_+\|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|143587
NZ_CP009896.1\|WP_082003930.1\|1373777_1374647_+\|DUF1295-domain-containing-protein	unknown	unknown	gnl\|CDD\|226275
NZ_CP009896.1\|WP_075018726.1\|1371611_1371899_+\|DUF2510-domain-containing-protein	unknown	unknown	gnl\|CDD\|378480
NZ_CP009896.1\|WP_038677368.1\|1362834_1364472_+\|succinate-semialdehyde-dehydrogenase-(NADP(+))	unknown	unknown	gnl\|CDD\|236501
NZ_CP009896.1\|WP_038677367.1\|1361155_1362613_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143457
NZ_CP009896.1\|WP_038677364.1\|1357750_1358152_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038677371.1\|1369865_1371464_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP009896.1\|WP_038677373.1\|1372285_1372777_+\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	2.30751e-32
NZ_CP009896.1\|WP_052139242.1\|1358856_1359978_+\|phosphotransferase-family-protein	gnl\|CDD\|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	1.45415e-65
NZ_CP009896.1\|WP_038677365.1\|1358148_1358724_-\|TetR/AcrR-family-transcriptional-regulator-C-terminal-ligand-binding-domain-containing-protein	gnl\|CDD\|379883	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal. This family of bacterial transcriptional repressors is characterized by the short approximately 50 amino acid stretch of residues constituting the helix-turn-helix DNA binding motif, around the YRFhY motif. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. Another target protein is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	5.92358e-11
NZ_CP009896.1\|WP_038677376.1\|1374643_1375762_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	1.28137e-30
NZ_CP009896.1\|WP_038677369.1\|1364474_1366187_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	1.11148e-59
NZ_CP009896.1\|WP_052138317.1\|1353047_1354556_+\|IMP-dehydrogenase	gnl\|CDD\|376340	pfam00478, IMPDH, IMP dehydrogenase / GMP reductase domain. This family is involved in biosynthesis of guanosine nucleotide. Members of this family contain a TIM barrel structure. In the inosine monophosphate dehydrogenases 2 CBS domains pfam00571 are inserted in the TIM barrel. This family is a member of the common phosphate binding site TIM barrel family.	0
NZ_CP009896.1\|WP_038677363.1\|1355923_1357030_+\|GuaB3-family-IMP-dehydrogenase-related-protein	gnl\|CDD\|236322	PRK08649, PRK08649, GuaB3 family IMP dehydrogenase-related protein.	0
NZ_CP009896.1\|WP_038677361.1\|1354555_1355059_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.51822e-12
NZ_CP009896.1\|WP_038677370.1\|1366474_1369765_-\|InlB-B-repeat-containing-protein	gnl\|CDD\|380193	NF033189, internalin_A, class 1 internalin InlA. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface or secreted proteins with an N-terminal signal peptide, leucine-rich repeats, and usually a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin A (InlA), a class 1 (LPXTG-type) internalin.	2.61872e-05
NZ_CP009896.1\|WP_038683694.1\|1357049_1357754_+\|carbon-nitrogen-hydrolase-family-protein	gnl\|CDD\|143587	cd07197, nitrilase, Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes. This superfamily (also known as the C-N hydrolase superfamily) contains hydrolases that break carbon-nitrogen bonds; it includes nitrilases, cyanide dihydratases, aliphatic amidases, N-terminal amidases, beta-ureidopropionases, biotinidases, pantotheinase, N-carbamyl-D-amino acid amidohydrolases, the glutaminase domain of glutamine-dependent NAD+ synthetase, apolipoprotein N-acyltransferases, and N-carbamoylputrescine amidohydrolases, among others. These enzymes depend on a Glu-Lys-Cys catalytic triad, and work through a thiol acylenzyme intermediate. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer. These oligomers include dimers, tetramers, hexamers, octamers, tetradecamers, octadecamers, as well as variable length helical arrangements and homo-oligomeric spirals. These proteins have roles in vitamin and co-enzyme metabolism, in detoxifying small molecules, in the synthesis of signaling molecules, and in the post-translational modification of proteins. They are used industrially, as biocatalysts in the fine chemical and pharmaceutical industry, in cyanide remediation, and in the treatment of toxic effluent. This superfamily has been classified previously in the literature, based on global and structure-based sequence analysis, into thirteen different enzyme classes (referred to as 1-13). This hierarchy includes those thirteen classes and a few additional subfamilies. A putative distant relative, the plasmid-borne TraB family, has not been included in the hierarchy.	7.45511e-52
NZ_CP009896.1\|WP_082003930.1\|1373777_1374647_+\|DUF1295-domain-containing-protein	gnl\|CDD\|226275	COG3752, COG3752, Steroid 5-alpha reductase family enzyme [General function prediction only].	5.07997e-33
NZ_CP009896.1\|WP_075018725.1\|1372906_1373290_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	1.3085e-18
NZ_CP009896.1\|WP_038677368.1\|1362834_1364472_+\|succinate-semialdehyde-dehydrogenase-(NADP(+))	gnl\|CDD\|236501	PRK09407, gabD2, succinic semialdehyde dehydrogenase; Reviewed.	0
NZ_CP009896.1\|WP_038677367.1\|1361155_1362613_+\|aldehyde-dehydrogenase	gnl\|CDD\|143457	cd07139, ALDH_AldA-Rv0768, Mycobacterium tuberculosis aldehyde dehydrogenase AldA-like. The Mycobacterium tuberculosis NAD+-dependent, aldehyde dehydrogenase PDB structure, 3B4W, and the Mycobacterium tuberculosis H37Rv aldehyde dehydrogenase AldA (locus Rv0768) sequence, as well as the Rhodococcus rhodochrous ALDH involved in haloalkane catabolism, and other similar sequences, are included in this CD.	0
NZ_CP009896.1\|WP_075018726.1\|1371611_1371899_+\|DUF2510-domain-containing-protein	gnl\|CDD\|378480	pfam10708, DUF2510, Protein of unknown function (DUF2510). This is family of proteins conserved in Actinobacteria. Many members are annotated as putative membrane proteins but this could not be confirmed.	3.58702e-08

>NZ_CP009896.1|WP_038677367.1|1361155_1362613_+|aldehyde-dehydrogenase
MTTLDRDALFIGGTWAAPAADAVLEVVSPHSEEVVARVPEGSTADIDAAVAAARRAFDEGPWPRMSPAERIDVVQNLSGLYAAKLDEMATIISTEMGSPISFSSLAQAPAPWMQIEAFLGIAREFPWEERRPGVLGADVVVRHEPVGVVAAIPPWNVPQFTILSKVVPALLAGCTVVVKPAPETPLDGYLLAELLVEAGVPEGVVSIVAGGREVGEHLVRHPGVDKVAFTGSTAAGRKIGAICGEQLKRVSLELGGKSAAIILDDADEAAAIEGLKFLGVMNSGQACVAQTRVLVSRERHDAFAASLAAAIGSMKVGDPLDPATEIGPMVAQRQQERVTSYIRIGQEEGAQLLAGGEGRPDGLDRGWYVRPTVFAGVDNKMRIAQEEIFGPVLSVIAYDDVADAIRIANDSEYGLAGTVWTADADAGLEVARGVRTGTYGINTYTMDFAAPFGGFKASGLGREFGPEGLAQYTEAKSVYLSAPPM
>NZ_CP009896.1|WP_052138318.1|1359974_1361159_+|hypothetical-protein
MSTRHDHGLHGEYYGLGPLDEYPIHQLPRPVAWAGSSDRNFYDRCYLNAHDRTGDLFLITGLGFYPNLGTKDAFVLLRRGDEQTAVHLSDAADPRGADRMAQQVGGYRVEIIEPLHKLRLVLEETEGVAMDLTWEGSFPVVQELPHVMRQGSGTTLDAQRFAQLGTWEGVLSVDGTDIAVTPDRWLGSRDRSWGIRPVGEAAPAGKPADPAFEGMWWLYVPLRFEEFCVVLIIQETPDGFRTLNDCTRIWKDGRVEQLGWPRVEIRYTPGTRVPTGATIVCTTPDGKELVLQVASKLPVPIHVGGGYGGDSDWTHGQWKGPAFTERLTYDMNDPAVAGRVMFGVIDHVGQATIHGPGAGVPEGSEGWGLFEHGALGRHDPSGFSDWFDLAKENS
>NZ_CP009896.1|WP_052139242.1|1358856_1359978_+|phosphotransferase-family-protein
MTLQRSSRDQGAVHDRLEEWLTAVLPDGAAPEVTLHEGIQTNGMSSETVLLAITTTEDGARVTREYVARVAPAASDLPVFAEYRLTDQYDAMRLAGELAGVPVPTVGLNEPTGDVLGTPFFLMDRLDGAVPPDVLPYPFGDNWLFDASPEQQERLQRSTVDVLARLHGIPDAATTFGFLDPAVTGHEGATPLARNLAKTRAWYEYAITTAEASPRSPLIERGLAWLEANLPAEEGEPVLVWGDSRIGNMMYRDFEPVAVLDWEMATLGPREMDLAWLVFAHQVFQEIATMLGLPGMPEFLAPDDVVATYRELTGVETGDLTWFLLHAAVNWGCVFLRTSARQIHFGEIERPDDPESVFHHRPLLERLLEEVGA
>NZ_CP009896.1|WP_038677365.1|1358148_1358724_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-ligand-binding-domain-containing-protein
MGTRSAGRPRDPRIEQAALAAVRSLLAEGGYGAVTVAAVAARAGTTKPALYRRWPALPHLVHEAAFPGELAGELRLGADLTTDLAGVVRGTRDALCDPVAAAALPGLLAEVSTWPDLHAAMLQRFAGVFRALDERLRTAVDAGEAHPDARADDLLRLVIDAVISGVLLTPDELDDAWVERLTGTLARSLRP
>NZ_CP009896.1|WP_038677364.1|1357750_1358152_+|hypothetical-protein
MRGRLERFVDAHPRTRATVIAALAVVIWAFDVPRIGVTRDLLGDRWAGVLGWGLGLGNVLAAVVAGAWFVRRRFAVAVAAVALCPFLLTHPRHGDDGIMSEADLIMVVGGDIVFGVVLLGLAGHTFRREPVRS
>NZ_CP009896.1|WP_038683694.1|1357049_1357754_+|carbon-nitrogen-hydrolase-family-protein
MIVAALQAEARSGDLAHNVATAARLVRQAEARVAVLPEAFLTGYDAAAFATPPTLATLSGPVLDPLRAAAAATGTTVVASAALARAAGRRTLSAIVVEPDGTVAAPYDKQHLDGDEPTWFVAGDHLATLTVDGRVLGLSICRDGSIPSHAAAAAAAGATVYLASVAYFPGGARRLDVTYAARALDHGLHVVVAGLTGRCGPHTFIGGSAVYAPDSTALVRLGDEEGVAVAEILG
>NZ_CP009896.1|WP_038677363.1|1355923_1357030_+|GuaB3-family-IMP-dehydrogenase-related-protein
MSDIEIGRAKRARRAYSFDDIAIVPSRRTRDPEEVSVDWQIDAYRFSLPILAAPMDSVMSPKTAIEFGRYGGLGVLNLEGLWTRFADPEPLLDEVAGLQGVEATRRLQEIYTEPIKAELIAERLREMRDAGVTVAASLSPQRTKEFAKAVTDAGVDLFVIRGTTVSAEHVSSQAEPLNLKEFIYELDVPVIVGGCATHQAALHLMRTGAAGVLVGFGGGAAHTTRTVLGVAVPMASAVADVAAARRDYLDESGGRYVHVIADGSIGTSGDLAKAIACGADAVMVGSPFARATDAPGRGFHWGAEAHHADLPRGQRVQFDQVGTIEEILFGPSRVADGTMNLVGALKRSMATTGYTELKEFQRVEVVAH
>NZ_CP009896.1|WP_038677362.1|1355048_1355879_-|hypothetical-protein
MSPRLVPALAVLALTVPVAACSDDEPRPRAAGTTPETGCPTAPAHAAESPLRSVARVDGVLYGVGTSGIDRLDGATPTRIHDEGPDLDLELVASYDGDLIVAANPGRTDPAPHVFRLTTDGDVVWDHAGPGAVVREPDPVISTGDAFVSLDTGKEVDWDDPVDVDEYVLEHEGRDYSLYDYSADARVYLDIRGGVAITAPSKKVLETMDGSAAVCGDRVYALSADRLRLTTYRLGDDGLEEVGEVVLPEPATQTAVRTTEGAVLLEVGGRTWVVSD
>NZ_CP009896.1|WP_038677361.1|1354555_1355059_+|GNAT-family-N-acetyltransferase
MSATIWPFVADDWPAVAAIIDEVLTAGETYAMPVLDDAAARNFWLDQPGVVAVAEVDGVVVGTAKMGPNRPAQGSHVGTASFMVGSAARGRGIGRALGEHVVAWHRAEGFAGIQFNAVVATNMAAVALWRSLGFEVIGTVPGAFRRPDGSFAGLHVMYLDLGAGLSR
>NZ_CP009896.1|WP_052138317.1|1353047_1354556_+|IMP-dehydrogenase
MGRVEVPDKFAALGLTYDDVLLLPGHSDLAPDDIDTTSRLTREISLKSPLISAAMDTVTESRMAIAMARQGGIGILHRNLSAEEQAYQVDLVKRTQTGIISNPVTIGPDATLEELDRICGEYRVSGLPVVDADNRLLGICTNRDLRFTPVAEWATTKVEEVMTPMPLFTGDVGISRDDATALLRKHKRERLPLVDAEGRLGGLITVKDFVKSEQFPLASKDADGRLLVGAAIGYFGDAWERATGLIEAGVDVLVADTAHGHVTLLLDMVRRLKSDPATKHVQVIGGNVATREGAQAFVDAGADAVKVGFGPGSICTTRVVTGCGVPQVTAVYEASLAAQPAGVPVIADGGLQQSGDIAKAIVAGAESVMIGSMLAGCEESPGEVVFHQGKQYKAYRGMGSLGAMSSRGKKSYSKDRYFQAEVTSDDKIVPEGIEGRVAYKGPLAGVAHQLLGGLSQSMFYVGAQSIPELQEKGRFVRITSASLKESHPHDIEMTVEAPNYHR
>NZ_CP009896.1|WP_038677368.1|1362834_1364472_+|succinate-semialdehyde-dehydrogenase-(NADP(+))
MSEAIPGSGADGSSGGPVVEGPHDPEHDPRASYVLEPEHVARLTARIVATTGTSAQVHSPINGAPLANIPQSSTEDVAEAFRRARVAQAAWARVSVDERARILHRLHDIVLDRQDEIMDLIQLESGKARKHAFDEPLHIALTARYYARTAHRHLDTQRRPGVVPVLTRVELNRVPKGVVGIISPWNYPFTMALCDGLPALLAGNAVVAKPDAQTMLSALLGAQLLEDAGFPRDLWQVVAGPGRELGTPIIERSDYICFTGSTATGKIIAKQAAERLIGCSLELGGKNPILVLRDADIERAAEGAVRACFSNAGQLCVSTERMFVADAVYDRFVERFVARTKAMSLGATMDWDADMGTLISADQLDTVTAHVDDAVAKGARVLAGGSARPDLAPYYFEPTILEGVTPEMTCFGNETFGPVVSIYRFHDEADAIARANDGEYGLNGSVYTRDTERGRQVARQIKCGTVNVNEAFGATFASIDAPMGGMRESGMGRRQGAEGIHRYTETQSVATQRLIRFGPMLGMSDEGYAKFMTASLRFMDKLGRA
>NZ_CP009896.1|WP_038677369.1|1364474_1366187_+|GMC-family-oxidoreductase
MTFDYDVLVIGSGFGGSVTALRLTEKGYKVGVLEAGARFSDADFAGNSWDLKKYLYAPSAGCYGIQRIDMVKDCLILAGAGVGGGSLVYANTLYEPLAPFYKDPSWSHITDWKAELAPYYDQAKRMLGVVEYPKMTPSDEVMKKVADEMGVGDSFHPTPVGVFFGGPEQAAGTQVEDPYFGGAGPRRNTCRDCGECMTGCRHNAKNTLVKNYLYLAEQNGADVHPLTTVTRVRPLAGGGYQVDTRWTKAKLSRRTATKTYTAEQVVFSAAALGTQKLLHRLKAEGDLPHVSDRLGHLTRTNSESILGAIAPQGADVDYTEGVAITSSWHPDEHTHIEPVRYGKGSNAMSLMQTVLTDGDGPDPRWKVWLKELWKERRRVRDLYDVKHWSERVVIALVMQSVDNSITTLPKKVAGKWILSSKQGHGEPNPTWIPAANDAVRRMAAVMGGGTAGGTIGEPFNRPLTAHFIGGCTIGDSPETGVVDGYQRMYGHPGLHIVDGSAISANLGVNPSLTITAQAERAMAFWPNKGEADTRPALGASYERIQPVAPQSPVVPDDAPAALRLPIVGVS
>NZ_CP009896.1|WP_038677370.1|1366474_1369765_-|InlB-B-repeat-containing-protein
MTCLPATGGPAAGLLVLGVALVAVGLVLTFPRRTTRVLTASLLVLAVVGASTFTPTEAHAASQDCVPGGTGADPGWSGAGDESDGPYDVTYSPGRGGRITGPAEQRVRAGQDAAPVRAVADAGHRFTGWSDGVTTPRRHDRDIDADLHVSARFAPLQHTLTYLAGPGGTLGGTTPQRVDHGSSGTAVTAVPDAGQRFVRWSDGSTANPRTDTDVTADLTVTAEFASATHRVRYLAGAGGTVTGDVDQTVAHGADATPVTALAGASHHFVRWSDGSTTNPRTDAAVVADLTVTAEFAVTLHRLQYVAGPGGSLTGDLDQQVQHGAAGSAVTAVPDAGRTFVQWSDGSTDNPRTDTAVIADATLTAVFATQTYVLTYAAAPGGSVSPAGPQVVDHGSNGPSVTASPQTGYRFVRWSDGSTANPRTDTGITANLTVTAEFAVRTYTVTYAAGPGGSLGGTTPQTVDHGTATTPVTAVPDTGYRFVRWSDGSTANPRTDNPVTADLTVTAEFAVRTYDLRYLAGAGGSVSGDTDQTVDHGSDGTPVTAVPDAGFRFVQWSDGSTTNPRTDAAVVADLTVTAEFDDALDLAVHESARGALTTTTPRDLVVTNPDAVEAEYVLVPTNTGAGTTDLTVAVAGNAPMPAANPGGTAVAADPHATSRRDAVALAQAARGSTGTGTPLSPPARLPSGTPTVGDPLRLNVDLDGSCTTGLAATATVQAVGTHVVIASDDSNPVGGFVDTDYTELLTTLDAMVPGVTGALGDLPDRDANDRVVVLVTRAVNELTPPATSTSDYVYSRPRDLLGQTACPTSNVGEIVYTMAPDPTGAVNSNVRTLSSVKGQIATGLAHELGHQIMDGVRLDAGTPLDGTWLAEAVADSALDAAFYARSVGLTPLQNLVLSNLTTGPNASLRVAAFNTYINADFTRYRPWLQAPTVNSVLAGTPSQASRGGAWAFLGYAADRKSGGSLSARTAFLRSLVTGPGTGTATLAAALGEAPGRWLEDFAVAAYTDDLVEAGPLGTSGPFAMLSWHFRSLYQALNVTYPLVPSALDADTSITRIYAPRGGSRHVLFRVAAGATATLTLTALTVNPEIGYRLVRLR
>NZ_CP009896.1|WP_038677371.1|1369865_1371464_+|glutamine-hydrolyzing-GMP-synthase
MTAAVENQPEHDHDHDLVLVVDFGAQYAQLIARRVREARVYSEIVPHTMPVAEMVARKPKAIILSGGPSSVYAEGAPTIDPAIFTSGPAVFGMCYGFQLMAAHLGGTVSATGAREYGRTRVTTSLPGTLLAGLPAEHNAWMSHGDSVSAAPDGFTVLASTEVTPVAAFENVDRGLAGVQWHPEVLHSEHGQKILEHFLWDIAGCRQTWTIGNIAEEQIARIRDQIGPDGRAICGLSGGVDSAVAAAIVQKAIGDRLTCVYVDHGLMRKGETEQIERDFVAATGAKLVIVDAEKQFLDALAGVSEPEAKRKIIGREFIRAFEGAELEVIKDAPEGTKVGFLVQGTLYPDIVESGHGAGTSTIKSHHNVGGLPEDLEFELVEPLRELFKDEVRAVGAQLGLPSVIVQRQPFPGPGLGIRIIGEVTRERLDLLREADAIAREEMTAAGLDGDIWQMPVVLLADVRSVGVQGDGRTYGHPVVLRPVTSEDAMTADWARLPYEVLEKISTRITNEVAEVNRVTVDITSKPPGTIEWE
>NZ_CP009896.1|WP_075018726.1|1371611_1371899_+|DUF2510-domain-containing-protein
MTGNPSQPGWYPDPSARNTQRYWDGDAWTDQMAPLAPEAKGSRPKEQFLPTWGLVLGIVLVIMFFMVVWAVQSGEAEDRKLCQSLEEAYPTGDSC
>NZ_CP009896.1|WP_038677373.1|1372285_1372777_+|Rrf2-family-transcriptional-regulator
MRMNEGVEWAAHVCVLLHWLHEDDGHDGPAPTPVARLAEAYDLPAAYLVKQVQALTRAGITESVPGKYGGVRLARPAGRITLMDVVAAIEGPDDAFACTEIRQRGMNEDRPARDFAKPCGIAHAMRGAELAWRRELAATSILDLAARTPRRVAADARRHFART
>NZ_CP009896.1|WP_075018725.1|1372906_1373290_+|carboxymuconolactone-decarboxylase-family-protein
MLALDGRLKEALGAVLYDLVKLRASQLNGCAYCVDMHATDLERRGVATRKIHGLAAWGESPFFEDDERVALAFTETLTGGIGAVDDDLWAEAGRVLGEERRADLIVAVGAINTWNMAGITTHLQPRP
>NZ_CP009896.1|WP_141267112.1|1373345_1373735_+|hypothetical-protein
MGGAGLPWMVLGGVAVVLACAGVLLMVPWIRAEQAREDELDRRDRDVLAYEVPNGQDPTAVLAALASAGLPAVPSLRHGHRVVLIDEQGRRDAVVRRQARRVIAAAPLNALGDPAPPHAVVFLDEGLPN
>NZ_CP009896.1|WP_082003930.1|1373777_1374647_+|DUF1295-domain-containing-protein
MTRVAIAYVLAFGAATGWLLWGPDTRWLWLDGLLGDLVATLVVFAASRVHRNSSFYDAYWSILPPYLALYWWLAADAARDDARAWLVLGVIALWAVRLTGNWIVTFPGLHHEDWRYPLVRARAGRLELLADLVGIHLVPTLQVFLGLVPAYVVLTRSGPGLRWLDGVALVVGVGAVVLAFVADRQMQRFARERTPGQVMDRGLWAWSRHPNYFGEISFWWSLALFGIAASPADWWWLPVGGVAMLAMFLGASIPMMEQRSLERRPAYREVVARVPVLVPRPPRSARSAG
>NZ_CP009896.1|WP_038677376.1|1374643_1375762_+|FAD-dependent-oxidoreductase
MSRPRVVVAGLGDSGLLTAIHLARADVDVVGISSKPGLVSGQELGMRLARPEAWARDYRVGFDRFRRLDGAELVHAELTRLDPATRTVTVDDGRATRAIDYDVLVVATGVSNGFWRRPALQTEAEVTATLAQAHEQIAGAATLLVVGGGAAAVASAYQCATRWPALRVTLAFPGERALPQHHPRTWAHVRRRLLAAGVELRPGHRAVVPEGFDCDRITAGPVAWSSGPEPLPADAVLWAIGRVRPNTGWLSADLLDDQGFVRVGPDLRIAGLQDAFAVGDVAATDPLRSSARNRADKLVAANVRAHLAGRPLGEFRPARRRWGSVLGVEDDGLRVFTPAGRPFRFPAWTVGAVLQPWIVRRGIYRGIRDLPR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_6

2112184-2112273

Orphan

Consensus_repeat	Method
GTTTCACCGCCTAGGCGGTGAAACTGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_6

>merge|NZ_CP009896|6|2112184-2112273|CRISPRCasFinder
GTTTCACCGCCTAGGCGGTGAAACTGCCCCTGGGCACAGGGAGTTCCGTGCGCCAACGACCGGTTTCACCGCCTAGGCGGTGAAACTGCC

>NZ_CP009896|6|6|2112184-2112273|CRISPRCasFinder
GTTTCACCGCCTAGGCGGTGAAACTGCC	CCTGGGCACAGGGAGTTCCGTGCGCCAACGACCG
GTTTCACCGCCTAGGCGGTGAAACTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038678052.1\|2110684_2112169_+\|PAS-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|378836
NZ_CP009896.1\|WP_038678062.1\|2116936_2117299_+\|nickel-type-superoxide-dismutase-maturation-protease	unknown	unknown	gnl\|CDD\|274282
NZ_CP009896.1\|WP_038678045.1\|2101566_2102583_+\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|187558
NZ_CP009896.1\|WP_038678046.1\|2102603_2103725_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379214
NZ_CP009896.1\|WP_141267221.1\|2105283_2106222_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP009896.1\|WP_141267223.1\|2114636_2115212_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_052138455.1\|2109695_2110553_-\|DUF2785-domain-containing-protein	unknown	unknown	gnl\|CDD\|371322
NZ_CP009896.1\|WP_082003621.1\|2117374_2118490_+\|NADP-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|223358
NZ_CP009896.1\|WP_052138457.1\|2114039_2114456_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235217
NZ_CP009896.1\|WP_141267222.1\|2112805_2113246_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038678050.1\|2107992_2109654_-\|acetolactate-synthase	unknown	unknown	gnl\|CDD\|235629
NZ_CP009896.1\|WP_052138453.1\|2106397_2107420_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP009896.1\|WP_038678060.1\|2116464_2116878_-\|superoxide-dismutase,-Ni	unknown	unknown	gnl\|CDD\|378114
NZ_CP009896.1\|WP_038678065.1\|2118511_2119486_+\|quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|176227
NZ_CP009896.1\|WP_038678043.1\|2100740_2101565_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368028
NZ_CP009896.1\|WP_038678054.1\|2112346_2112601_-\|WhiB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376791
NZ_CP009896.1\|WP_075018552.1\|2113221_2114043_-\|RNA-polymerase-sigma-factor-SigF	unknown	unknown	gnl\|CDD\|274373
NZ_CP009896.1\|WP_038678048.1\|2103721_2105197_+\|oligosaccharide-flippase-family-protein	unknown	unknown	gnl\|CDD\|240533
NZ_CP009896.1\|WP_038684062.1\|2107607_2107976_-\|thioesterase	unknown	unknown	gnl\|CDD\|227783
NZ_CP009896.1\|WP_141267224.1\|2115448_2116210_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|172341

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038678052.1\|2110684_2112169_+\|PAS-domain-containing-sensor-histidine-kinase	gnl\|CDD\|378836	pfam12282, H_kinase_N, Signal transduction histidine kinase. This domain is found in bacteria. This domain is about 150 amino acids in length. This domain is found associated with pfam07568, pfam08448, pfam02518. This domain has a single completely conserved residue P that may be functionally important. This family is mostly annotated as a histidine kinase involved in signal transduction but there is little published evidence to support this.	9.00593e-62
NZ_CP009896.1\|WP_038678062.1\|2116936_2117299_+\|nickel-type-superoxide-dismutase-maturation-protease	gnl\|CDD\|274282	TIGR02754, putative_signal_peptidase, nickel-type superoxide dismutase maturation protease. Members of this protein family are apparent proteases encoded adjacent to the genes for a nickel-type superoxide dismutase. This family belongs to the same larger family (see pfam00717) as signal peptidase I, an unusual serine protease suggested to have a Ser/Lys catalytic dyad. [Cellular processes, Detoxification, Protein fate, Protein modification and repair].	4.44255e-18
NZ_CP009896.1\|WP_038678045.1\|2101566_2102583_+\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|187558	cd05247, UDP_G4E_1_SDR_e, UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	8.0281e-118
NZ_CP009896.1\|WP_038678046.1\|2102603_2103725_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379214	pfam13480, Acetyltransf_6, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions.	8.81511e-10
NZ_CP009896.1\|WP_141267221.1\|2105283_2106222_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.99734e-06
NZ_CP009896.1\|WP_038678060.1\|2116464_2116878_-\|superoxide-dismutase,-Ni	gnl\|CDD\|378114	pfam09055, Sod_Ni, Nickel-containing superoxide dismutase. Nickel containing superoxide dismutase (NiSOD) is a metalloenzyme containing a hexameric assembly of right-handed 4-helix bundles of up-down-up-down topology with an N-terminal His-Cys-X-X-Pro-Cys-Gly-X-Tyr motif that chelates the active site Ni ions. NiSOD catalyzes the disproportionation of superoxide to peroxide and molecular oxygen through alternate oxidation and reduction of Ni, protecting cells from the toxic products of aerobic metabolism.	1.69316e-61
NZ_CP009896.1\|WP_052138455.1\|2109695_2110553_-\|DUF2785-domain-containing-protein	gnl\|CDD\|371322	pfam10978, DUF2785, Protein of unknown function (DUF2785). Some members in this family are annotated as hypothetical membrane spanning proteins however this cannot be confirmed. The family has no known function.	6.02225e-54
NZ_CP009896.1\|WP_082003621.1\|2117374_2118490_+\|NADP-dependent-malic-enzyme	gnl\|CDD\|223358	COG0281, SfcA, Malic enzyme [Energy production and conversion].	4.97235e-177
NZ_CP009896.1\|WP_052138457.1\|2114039_2114456_-\|hypothetical-protein	gnl\|CDD\|235217	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional.	5.83802e-14
NZ_CP009896.1\|WP_038678050.1\|2107992_2109654_-\|acetolactate-synthase	gnl\|CDD\|235629	PRK05858, PRK05858, acetolactate synthase.	0
NZ_CP009896.1\|WP_052138453.1\|2106397_2107420_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.85026e-06
NZ_CP009896.1\|WP_038678065.1\|2118511_2119486_+\|quinone-oxidoreductase	gnl\|CDD\|176227	cd08266, Zn_ADH_like1, Alcohol dehydrogenases of the MDR family. This group contains proteins related to the zinc-dependent alcohol dehydrogenases. However, while the group has structural zinc site characteristic of these enzymes, it lacks the consensus site for a catalytic zinc. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	9.50037e-97
NZ_CP009896.1\|WP_038678043.1\|2100740_2101565_+\|hypothetical-protein	gnl\|CDD\|368028	pfam04625, DEC-1_N, DEC-1 protein, N-terminal region. The defective chorion-1 gene (dec-1) in Drosophila encodes follicle cell proteins necessary for proper eggshell assembly. Multiple products of the dec-1 gene are formed by alternative RNA splicing and proteolytic processing. Cleavage products include S80 (80 kDa) which is incorporated into the eggshell, and further proteolysis of S80 gives S60 (60 kDa).	0.00543515
NZ_CP009896.1\|WP_038678054.1\|2112346_2112601_-\|WhiB-family-transcriptional-regulator	gnl\|CDD\|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	2.4403e-28
NZ_CP009896.1\|WP_075018552.1\|2113221_2114043_-\|RNA-polymerase-sigma-factor-SigF	gnl\|CDD\|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	5.82175e-116
NZ_CP009896.1\|WP_038678048.1\|2103721_2105197_+\|oligosaccharide-flippase-family-protein	gnl\|CDD\|240533	cd13128, MATE_Wzx_like, Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.01048e-39
NZ_CP009896.1\|WP_038684062.1\|2107607_2107976_-\|thioesterase	gnl\|CDD\|227783	COG5496, COG5496, Predicted thioesterase [General function prediction only].	2.36616e-17
NZ_CP009896.1\|WP_141267224.1\|2115448_2116210_-\|hypothetical-protein	gnl\|CDD\|172341	PRK13808, PRK13808, adenylate kinase; Provisional.	1.10987e-06

>NZ_CP009896.1|WP_038678052.1|2110684_2112169_+|PAS-domain-containing-sensor-histidine-kinase
MPSLSAIARRHTDLDEGDIAWIQLIQADWQVIADLSFADLVLWLPDRGGKGFWVGDQMRPTTGPTAYVDDIVGTFSPAGRRTLVDAAFELGRIAREGDPEWRDEVPVRVEAIPVRRNGRVIAVISRNTNLLGIRTPSHLEINYLQAASDLANMIASGYFPTEAQRSDHADSPRVGDGFLRVDAEGRVIYASPNALSVYRKLGLTGDLTGHRLTDLTRDLVAPKKRPDEETLSAVLGGRAHRDTELGASSVGGPGDGAALIVRAIPLRPKGEHIGAIILLRDVTDLRRRDRELVTKDATIREIHHRVKNNLQTVAALLRLQARRIGSPEAASALEEAVRRVGSIAIVHETLSQAVEETVAFDDIADRLARLVTDVGSTTAQVRVRREGSFGVLVSEVATPLAMVVMELMQNAAEHGYDGGGSGEIVVRAARHGAVLEVAVEDDGCGLPDGFDLDAATSLGLSIVRTLVESELGGHLTLGPAPDHGTRASFSLPVD
>NZ_CP009896.1|WP_052138455.1|2109695_2110553_-|DUF2785-domain-containing-protein
MVSVDWARLQQALRDGQRRPPSDHPLGDLTAQLTHMLGDPDPQVRDGLAYSFLATWIEHGVYDDLLAGLGDGMCAGLNTGLGERDTDTVFRRSFSVLLLAECIERDARIRRLPPSRVLHWGDRIAAWYVRERDLRGFVPGKGWAHAAAHGADALAALARARHFGMTELTVLLDVIADRVLSPDTPPLVHGEPDRIAHAVMEVLRRDRVPLNVLEPWVVRLERGARAKPPAGRDPYRATGNAQAVLRALYLQLTISPRHPAVRPDLLLALVASLRRVHPYFLDDIR
>NZ_CP009896.1|WP_038678050.1|2107992_2109654_-|acetolactate-synthase
MTTPPDSLTGHAGEIAVAVAQAHGVETMFTLSGAHVFPMYDGAVKSEPPVRLLDVRHEQTAAFAAEATGKLTRVPGLAVLTAGPGVTNGVSAMAQASFAGSPMVVVGGRAPANRWGTGALQEIDHLPIVAPVTKHAATLMTANDVAAGFDQAFTQARSSHRGPAYVDVPMDAFFDAGTGPAPVLGAYRGAEPDSDAVARIAGLVARAERPVLILGTDVWADHAEEAALRLVEEMRLPAITNGMGRGVVPGGHPLLVTKARGAALNGADLVVVVGTPLDFRLGYGVFGGKDGGTPAAVVHIADSPGQLSGHADLAASVSGDLSAVLDGLLSALAGAAQPDRADWLTLLQDTVAAASARDAALLSAEADPVHPARIYGELVPRLADDAVVIGDGGDFVSFAGKFVEPKRPGCWLDPGPYGCLGAGLGAAIAARIARPSAQVVLLLGDGAAGFSLMDVDTLVRHGLPVVMVMGNNSAWGLEKGPMQMLYGYDVAADLAPRTAYDEVVRALGGAGETVTDPRHIGPALDRAFAANAPYLVNVITDVDAAYPRATFGI
>NZ_CP009896.1|WP_038684062.1|2107607_2107976_-|thioesterase
MTFTVTDADTALALGSGSLPVLGTPRLLAWCEAATCAAVEDSLGSGETSVGTRVELEHLAATGVGGSVEVTAREVYADGRLRRYAVAARNRGADGRPGKLVGSGEVTRVVVDADRFLARISG
>NZ_CP009896.1|WP_052138453.1|2106397_2107420_+|helix-turn-helix-transcriptional-regulator
MLRPSTPSAPTPAVPAVRAAPFSLLTQYERRAEQPIGAFKAGVIRDVLARQEQVPEHHQLLWGRFLTVLEQRGSDGRSLVLCAVLANFVALVVFDDPDDLAAAAGLGERLGADRVGRLQHRVARMLETRADLPWTTAVARRLLAPMLAQRTADGDGEGTGAGTGDGEGDDVVAGCLELGRELLFQPIDPQPVGVAVDEVVPIDSADELVTLLEQGSLVEWRRHLQRLATSPWGPYAESISELADAADRPAIHTVLAWCRAWGHDREREQIARHVQHLVAVSGVSQRQFAARIGTSPSRLSSYIRGSVTPSAALFLRIQRASRALQVPAAAAGPAPSSQGA
>NZ_CP009896.1|WP_141267221.1|2105283_2106222_+|helix-turn-helix-domain-containing-protein
MVLREWERRQVRGIITSFEHRAAGAGAGAGAGAGAGAGALRRWARASAALSATDDDAPILAARAVLANALALIHFPEPRDVDDLARLVAQHGGSQVARLQESALAAIDTGERPLTTHLVRVLAGYAWGGPDTPLRPDGRTEREELAGACVVRLLLVGDASGPPPPITDANDLRAVFEDHALPAWRAVVAARVGDPWDGTAERHLGLLDPVSQPFEVASIRAVVELSRREAEEDERRAVASHIRSTIDQTGLTQREFAALVGTSPSRLSTYVTGTVTPSAAMLLRINRAARRAQRAGRDRDRDPDLGVPEPGR
>NZ_CP009896.1|WP_038678048.1|2103721_2105197_+|oligosaccharide-flippase-family-protein
MTSESEQDQQAEQAALLRRTGAAVLTLAVAELLGKVATFVTFLLLARILGVAEFGVLSFGWSLGLLLAVFSSLGLEARLTQLGSARPELLDRCYGALVAIRLGLCAVVLVPTTGLLFGTMSTTHALTVTFLVAAGLADTLVDASRAACGARQRQHLSAVVLVVQRFSALILSVGVLVVTESVWCAALGYLVATCIGVLGMHLAARRAGVRMRIRGSRAEARMILEAAPVMGLGAVAAMGMFRIDAALIGMILGTTAVGVYGAGYRIFETVLFVSWTLARAYVPVIASRPDDTEHVRRWAQRSLVVVAAVYVPYGVLLATRGDDLVGLLFGPEYVHRGLLWGLAVAPLLFGVSYLGSTVLLALRPDPVVLVGSVAALVANIGLNLWLIPVWGITAAAVATSVAFLVQSVVVVRALTRTVGSIVSVPELVAVLVAAVVVGLVLEAVGPLLPALAVAGLAYVVVAVLAVHRLAPSALGRLRTGLRRTPVAGSRI
>NZ_CP009896.1|WP_038678046.1|2102603_2103725_+|GNAT-family-N-acetyltransferase
MPPRTTVATVLTEVAHGAAARAALADLAPYVEGRSSAFSTGAGWLAAAARHLPGEPVTIVLREPGSPGSTASPGRVVALAPLVVRRRTGVLRVEVLGGELNDYAELFHDDPEAADLLAGAIVAWLRGQRRWSLRLSQLAPEDPVLAGLLARLPGAAVVPGPPMPRIEGAGTDYRLTRHRRRKINTDLNRLAADGHHAERLVVDDPEALERWLPRLVEVRRGRDHGSGRRSHLDDDGTRAFHEEVVRDAMARGRAVVDLLVVGDEVLGFTTTLRDGPVSRLFDGRVAQDWMRYRGGIVCEMAAVQRAIDDPEVVTFDWLRGRTDAKFGNAEIHRAELRASSHAWIDRLDDARARARARVKELLPAGLVHRIVER
>NZ_CP009896.1|WP_038678045.1|2101566_2102583_+|UDP-glucose-4-epimerase-GalE
MDVLVTGGAGYIGSTVASALADAGHRPVVLDDLSTGRAEFVRGRRFYRGDIADAGLVRRIVAEHPGLRTAVHCAARVAVPESVARPADYYRTNVTGTLELAQTLAEAGVRDLVLSGSASVYGPAGAAGVDEDAPWAPASPYARTKAVAELMLADLAAATRLRVLSLRYFNPVGADPQLRTGPQQPRPGHVLGVLAESLRTGASFPVRGTDYPTRDGSALRDYVHVWDLARAHVAAVEGFERALDGRRSQAINLGTGRGTTVHELVATFAAVTGRPVPVVAAPRRPGDTAGTFARTERAAYLLGWHAERDLATGIADLLAWLERRPALLENPALVGSSR
>NZ_CP009896.1|WP_038678043.1|2100740_2101565_+|hypothetical-protein
MSPWSEKRGPRWPLFAGIGCVLAGLIGGFLLMYGVDRGADDPDPAPDPVPSSPAPSDASPPPASPSSSPSPTAPDASGLTVVSWGQEGGQLAVVVRNDTDEVIERARVLLTARDRSGAAVLSTSGTPDDVCCTVVGLAPGAEFGLFAELRSPLRDVAEVEARPVARDLRTGDGAVPAVRVRDARLRHLPDDTVVTARLTAEGDLSGYVAAQALLVDADGRVVQVVSGRFYCFASGRPGTVRLRLFHAVPRDLRLGRVLAQAIPQGVPPGVPGRC
>NZ_CP009896.1|WP_038678054.1|2112346_2112601_-|WhiB-family-transcriptional-regulator
MDWRHRSACLDEDPELFFPIGNTGPAILQIEEAKAVCRRCDVREQCLAWALEAGQDHGVWGGLSEDERRALKRRNARARVRTPV
>NZ_CP009896.1|WP_141267222.1|2112805_2113246_+|hypothetical-protein
MTDRPAARPATNPPPLIVAASVAGVQGAVLLLLAILEFASVTSGRLAFGLSTAGFFAAYGVVLMVAAVALWRRQGWSRGPVLITQLIFLGLAWNLREHVLVAIVLAVVALVVLAGMVSKDTLAALDGTTDADDADDDPDQPSASSD
>NZ_CP009896.1|WP_075018552.1|2113221_2114043_-|RNA-polymerase-sigma-factor-SigF
MTADVSRDGAEGGPPLTGVELTRRRSAELFVVLRDEDASAAERDSARDALVHLHLPLVEHCARRFRNRGEPYEDLVQVGTIGLIKSVDRFDTERGVEFSTYATPTIIGEIKRYFRDKGWAIRVPRRLQELRMQITATTAELTQSLGRSPTPRELADSIGCSVEEIVEGLESSNAYSTLSLDATDDDSDGGAGQSMLDAMGVDDAGLEHVEIRESVKPLLENLPAREKKILLLRFFKNMTQSQIAEEIGVSQMHVSRLLSRTLAQLRQSLEADG
>NZ_CP009896.1|WP_052138457.1|2114039_2114456_-|hypothetical-protein
MSETSTLAAGGVTDDPDEVELRLPADGAYASVLRTLTAGLAARVDFTMDDIEDLRIAVSEAAAMVLDEADDDAVLDCRFQLGAGRLAMTIATTAAAPSSPDYESFGWQVLATLADQAAIDAAPGRYAVRLVVRSSLPA
>NZ_CP009896.1|WP_141267223.1|2114636_2115212_-|hypothetical-protein
MLRAISKMIVGIAVALGLTLAAAPVASAAPAPTAERTAERAPNCTVQFQAYKIATSTHTTAKANVSKLKAKVAKLKKKIKKAKRAHHPRKVAHYKKVLKKTKKKLNRAKVVRTKAATAVSSTTRAFAACERGEGPTLPTEPTDGNLLAFLGEILDSLGIGALVDLLGLKTVVDLLNLRPLLVGLGLGALLD
>NZ_CP009896.1|WP_141267224.1|2115448_2116210_-|hypothetical-protein
MNRALVKMFLGLAVALGLTLAAAPVASAAPTAAGTASAAAAAPDCTRQQAAHNRATAAYNSAHRAVKAAQAKVKKLTKKVKKAKKAHAKKQVKKLNKKLRKAKKSLRAKKEYRSKVAITRTYTARSLARCQSGQAATGSESPIQALCDAGLPQPLCDALANLIPGGSTTNPIGLLCAQFPQAKPLCDLVATGLPTDPTDLLDIVEGLLVTLGLGDLLDTLLDGLGLGTLGDLLNGTGLDDLLDLLGLGGLLHP
>NZ_CP009896.1|WP_038678060.1|2116464_2116878_-|superoxide-dismutase,-Ni
MFSRLTTLLVAPTVEVSAHCDLPCGVYDPAQARIEAESVKAVIAKALDSDDPDFRTRAILIKEQRSELVKHHLWVLWTDYFKPPHFEKYPQLHTLVNEATKLAGATGTKGTLDAAKADELLAKIDEIAEIFWETKKA
>NZ_CP009896.1|WP_038678062.1|2116936_2117299_+|nickel-type-superoxide-dismutase-maturation-protease
MDPAATAGRTSGRRIGLAVVTGDSMRPTLRPGDRLVVTYGARVRAGQVVVARFADGTLVVKRATERRGSGWWLRGDNPDPGVGVDSRHRGPVPDRAVLGVVRGRLWPRPRRLGAFEDVKE
>NZ_CP009896.1|WP_082003621.1|2117374_2118490_+|NADP-dependent-malic-enzyme
MATVPTADVSTKDQLSLAYTPGVAEVCEAIAADPALTRHYTWVPNTVAIVTDGTAVLGLGDIGPAAAMPVMEGKAVLFKQFGGVDGIPICLATTDVEEIIETVVRLAPSFGGINLEDISAPRCFEIEDRLKEALDIPVFHDDQHGTAVVTLAALVNALKLTGRSVESTRVVISGAGAAGVAIAKILLAAGVKDIAVTDRKGVVSSDRTDLTPSKKALAELTADQCGRRGTLAEAFDGADVYIGVSGGTVPEEVVATMADDAIIFAMANPNPEVHPEVAHRHARVVATGRSDFPNQINNVLAFPGIFRGAFDVHASAITEGMKVAAADALAALVGDDLSEDLVIPSPFDPRVGPAVAAAVADAARRDGVARI
>NZ_CP009896.1|WP_038678065.1|2118511_2119486_+|quinone-oxidoreductase
MLAVYADSFASSPDDPLTGLVVGERPDPVAPDGWTTVTVKAAALNHHDLWSLRGVGLKAEALPMILGCDAAGYDEDGNEVVVHAVVSDPDWTGDETLDPRRSLLSERYQGTLAEQVVVPRRNVVPKPASMSFEEAACLPTAWLTAYRMLFTQGGLTPGETVLVQGAGGGVATALIALARAGGLRVLATSRDEAKRAKALELGAHEVFESGARLPVKVDAVMETVGRATWTHSVRALRPGGRIVISGTTSGPNVDDAELTRIFFTQLSVIGSTMGTRGELAALVNLLDSTGLRPVIDRVLPLEQARDGFAAMAAGDVFGKVVFTR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_7

2890107-2890232

Orphan

Consensus_repeat	Method
CGGCAGTTTCACCGCCTAGGCGGTGAAACTGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_7

>merge|NZ_CP009896|7|2890107-2890232|CRISPRCasFinder
CGGCAGTTTCACCGCCTAGGCGGTGAAACTGCCCTCACCGCCTGACTGGCCGCCCGAAACTCCCCCTGGGCACACGGAGTTCCCGCTGCCCACCGGCAGTTTCACCGCCTAGGCGGTGAAACTGCC

>NZ_CP009896|7|7|2890107-2890232|CRISPRCasFinder
CGGCAGTTTCACCGCCTAGGCGGTGAAACTGCC	CTCACCGCCTGACTGGCCGCCCGAAACTCCCCCTGGGCACACGGAGTTCCCGCTGCCCAC
CGGCAGTTTCACCGCCTAGGCGGTGAAACTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038679098.1\|2884031_2884526_-\|Rieske-(2Fe-2S)-protein	unknown	unknown	gnl\|CDD\|239550
NZ_CP009896.1\|WP_038679107.1\|2890250_2890772_+\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|185291
NZ_CP009896.1\|WP_141267293.1\|2884597_2885479_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038679120.1\|2896490_2897516_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173838
NZ_CP009896.1\|WP_075018624.1\|2883625_2884039_-\|Rieske-(2Fe-2S)-protein	unknown	unknown	gnl\|CDD\|239550
NZ_CP009896.1\|WP_038679102.1\|2885529_2888535_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP009896.1\|WP_038679116.1\|2894055_2895210_-\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl\|CDD\|239607
NZ_CP009896.1\|WP_038679104.1\|2889406_2890078_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293792
NZ_CP009896.1\|WP_052138678.1\|2890749_2890929_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_141267292.1\|2892620_2893718_-\|ferredoxin--NADP-reductase	unknown	unknown	gnl\|CDD\|99810
NZ_CP009896.1\|WP_052138676.1\|2882877_2883660_+\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|366030
NZ_CP009896.1\|WP_038679110.1\|2891726_2892074_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|380093
NZ_CP009896.1\|WP_038679108.1\|2891028_2891640_-\|DNA-3-methyladenine-glycosylase-I	unknown	unknown	gnl\|CDD\|377025
NZ_CP009896.1\|WP_038679118.1\|2895282_2896473_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173841
NZ_CP009896.1\|WP_038679114.1\|2893742_2894045_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_052138672.1\|2879526_2881533_-\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NZ_CP009896.1\|WP_052138677.1\|2888697_2889384_+\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl\|CDD\|236578
NZ_CP009896.1\|WP_038679112.1\|2892152_2892542_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
NZ_CP009896.1\|WP_038679096.1\|2881570_2882881_+\|pyridine-nucleotide-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|100115
NZ_CP009896.1\|WP_038679093.1\|2878652_2879522_-\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|235450

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038679098.1\|2884031_2884526_-\|Rieske-(2Fe-2S)-protein	gnl\|CDD\|239550	cd03467, Rieske, Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.	9.1249e-25
NZ_CP009896.1\|WP_038679107.1\|2890250_2890772_+\|NUDIX-domain-containing-protein	gnl\|CDD\|185291	PRK15393, PRK15393, NUDIX hydrolase YfcD; Provisional.	2.80297e-36
NZ_CP009896.1\|WP_038679120.1\|2896490_2897516_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	6.10616e-32
NZ_CP009896.1\|WP_075018624.1\|2883625_2884039_-\|Rieske-(2Fe-2S)-protein	gnl\|CDD\|239550	cd03467, Rieske, Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.	2.10608e-17
NZ_CP009896.1\|WP_038679108.1\|2891028_2891640_-\|DNA-3-methyladenine-glycosylase-I	gnl\|CDD\|377025	pfam03352, Adenine_glyco, Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.	2.36117e-100
NZ_CP009896.1\|WP_038679116.1\|2894055_2895210_-\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl\|CDD\|239607	cd03531, Rieske_RO_Alpha_KSH, The alignment model represents the N-terminal rieske iron-sulfur domain of KshA, the oxygenase component of 3-ketosteroid 9-alpha-hydroxylase (KSH). The terminal oxygenase component of KSH is a key enzyme in the microbial steroid degradation pathway, catalyzing the 9 alpha-hydroxylation of 4-androstene-3,17-dione (AD) and 1,4-androstadiene-3,17-dione (ADD). KSH is a two-component class IA monooxygenase, with terminal oxygenase (KshA) and oxygenase reductase (KshB) components. KSH activity has been found in many actino- and proteo- bacterial genera including Rhodococcus, Nocardia, Arthrobacter, Mycobacterium, and Burkholderia.	1.672e-74
NZ_CP009896.1\|WP_038679104.1\|2889406_2890078_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	1.12283e-37
NZ_CP009896.1\|WP_038679102.1\|2885529_2888535_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP009896.1\|WP_141267292.1\|2892620_2893718_-\|ferredoxin--NADP-reductase	gnl\|CDD\|99810	cd06214, PA_degradation_oxidoreductase_like, NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like domain with an iron-sulfur binding cluster domain. Ferredoxins catalyze electron transfer between an NAD(P)-binding domain of the alpha/beta class and a discrete (usually N-terminal) domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal portion may contain a flavin prosthetic group, as in flavoenzymes, or use flavin as a substrate. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria and participate in a wide variety of redox metabolic pathways. The C-terminal domain contains most of the NADP(H) binding residues and the N-terminal domain interacts non-covalently with the isoalloxazine rings of the flavin molecule which lies largely in a large gap betweed the two domains. Ferredoxin-NADP+ reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	9.38437e-98
NZ_CP009896.1\|WP_052138676.1\|2882877_2883660_+\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|366030	pfam00326, Peptidase_S9, Prolyl oligopeptidase family.	6.23977e-07
NZ_CP009896.1\|WP_038679110.1\|2891726_2892074_+\|VOC-family-protein	gnl\|CDD\|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	1.97312e-28
NZ_CP009896.1\|WP_038679118.1\|2895282_2896473_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	5.72282e-135
NZ_CP009896.1\|WP_052138672.1\|2879526_2881533_-\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NZ_CP009896.1\|WP_052138677.1\|2888697_2889384_+\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl\|CDD\|236578	PRK09583, PRK09583, mycothiol-dependent maleylpyruvate isomerase; Reviewed.	2.82535e-42
NZ_CP009896.1\|WP_038679112.1\|2892152_2892542_+\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.00297222
NZ_CP009896.1\|WP_038679096.1\|2881570_2882881_+\|pyridine-nucleotide-disulfide-oxidoreductase	gnl\|CDD\|100115	cd05804, StaR_like, StaR_like; a well-conserved protein found in bacteria, plants, and animals. A family member from Streptomyces toyocaensis, StaR is part of a gene cluster involved in the biosynthesis of glycopeptide antibiotics (GPAs), specifically A47934. It has been speculated that StaR could be a flavoprotein hydroxylating a tyrosine sidechain. Some family members have been annotated as proteins containing tetratricopeptide (TPR) repeats, which may at least indicate mostly alpha-helical secondary structure.	1.80515e-58
NZ_CP009896.1\|WP_038679093.1\|2878652_2879522_-\|RNase-adapter-RapZ	gnl\|CDD\|235450	PRK05416, PRK05416, RNase adapter RapZ.	4.39799e-147

>NZ_CP009896.1|WP_038679104.1|2889406_2890078_+|MBL-fold-metallo-hydrolase
MTYTGEVTVGGAPAIRELANLTITKVAVDEKMSNNCYLLRCHDTGSQVLIDAAAAPETLLPLIGDEGVTTVITTHQHWDHHRALADVVRASGAGVVAGEPDADAITEQTGVSVDRRVTDGDEIMVGSCALQVIRITGHTPGSICLLYRDPAGHPHLFTGDSLFPGGVGGTFGDADAFRSLIDDVETKIFDTLPDDTWFYPGHGSDGTLGEQRPHLAEWRERGW
>NZ_CP009896.1|WP_052138677.1|2888697_2889384_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MTTLSAATERLLTTAASLSDDAWAAPSLCAGWSRAHVLAHLALNAEGLGGILRGLRDGVPRTMYVSEERRDGDIDDLVAAAGPAAILDRLRSAVAGLAEVVDVATVLPEGTTFERTPGGRQMSANNVPFLRLREVEIHHADLGAGYTASDWPPTTATSFLTASSRQYAGPGFHVVATDEPARWTFGTPAEGAATVSGPVGPLAWWATGRDADGAVTSSAGALPDLTSA
>NZ_CP009896.1|WP_038679102.1|2885529_2888535_-|excinuclease-ABC-subunit-UvrA
MTDQLIIRGAREHNLKDVSIDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTSKNPRSTVGTITEVYDYLRLLYARAGRAHCPTCGAPIEQQTPQQIVDRMLELDEGTRFQVLAPVVRGRKGEYVELFKQLQTQGFSRARVDGETHNLDSPPTLDKKLKHTIEVVVDRLAVKASAKRRLTDSVETALGLAGGLVVFDLVDAGQELKFSEKMACPNDHPIETDDLEPRSFSFNSPFGACPSCSGLGTRMEVDPELVVPDPTATLAEGALQPWSHAHVADYFGRLLVALGDELGFDVDTPWEQLTTRAQRAILDGHATKVHVVTRNRYGRERSYYADFEGVRKYVERRHREAESDTSRERFEGFMREVPCPVCSGSRLKPVSMAVTLGAKDKGGKNIAEVCALPINETAAYLADLDLSARERQIGERVLKEIQERLNFLLDVGLDYLSLDRPSGSLSGGEAQRIRLATQIGAGLVGVLYVLDEPSIGLHQRDNQKLIETLVRLKDLGNTLIVVEHDEDTIRVADWIVDIGPGAGEHGGQVVHSGTVKELLEHPDSMTGQYLSGRREIPVPAIRRPRTVGRELKVLGAREHNLKNVDVAFPLGVFTAVTGVSGSGKSTLVNDILYTSLAKQIYNARTIPGRHQKITGLEHVDKVIHVDQSPIGRTPRSNPATYTGVFDHVRKLFAQTPEAKMRGYQQGRFSFNVKGGRCEACAGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIAEVLDMPIEEAQDFFAAVPAIARHMTTLTEVGLGYVRLGQPATTLSGGEAQRVKLAAELQKRSTGRTVYVLDEPTTGLHFEDIRKLLGVLSGLVDKGNTVLVIEHNLDVIKTADWIIDMGPEGGSRGGTVVAEGTPEEIAAVAESHTGHFLRPLLDGRGAAQPGAPKRAPKAAVDAKKTPAAKKAAAKKTAARKVAAVKKSTTGTARKRKA
>NZ_CP009896.1|WP_141267293.1|2884597_2885479_-|hypothetical-protein
MTRRTRGRSVPALLLGLLLASSLLAGVAEAAGASAATTSAAAPQLRCEIDAYGHTRDGRIHLRKITGNRVTVAKATARPVSWRPVAWGLVMLNSWPGHEETHQVVAATDGKVRLVRTEWNTRGSLRTTVLKVLGSGYPSRLIAFNDRSLYWVATDGLLHRATWNGRRLVRPRALPVPIRQATTLTAATTERGGSRVYYTDRAGALHVVRDEGAQSTDTVLRTSGYAAVTALRSGTCIDDRYTGAPVPGVLLVVDRTTGVARVQRVLRPDDASGGTLAAPVRVRPGGWTWRRLG
>NZ_CP009896.1|WP_038679098.1|2884031_2884526_-|Rieske-(2Fe-2S)-protein
MTSSLSRRRALSGAATLGVGVPLLAACGSGDDGAAKDPATDPATDAPSTPSSPTATETASGTPSSGGGGAGGLVATADVPVGGGVIIKDAELVVTQPSAGQFKAFSAICTHQGCLVGSVSDGQIHCPCHGSSFSVSDGASQGGPAQTPLPEVAVTVSGDEVTRA
>NZ_CP009896.1|WP_075018624.1|2883625_2884039_-|Rieske-(2Fe-2S)-protein
MPEVRVPRRIVFSGLGALGVAVALAGCAGGDDGGSGKPKVAAGDELTTTDQVPVGGGIVLTDAKVVVTQPSAGKFEAFTAVCTHQGLTVTSVADGRIQCAHHGSSYSISTGEVEGGPAPSALASVAIKQDGQRILAA
>NZ_CP009896.1|WP_052138676.1|2882877_2883660_+|prolyl-oligopeptidase-family-serine-peptidase
MTAEDAAWERIDAASAAHSPAPLVRYGTDADQVAETYGTGAGAGTPVIVLVHGGYFRPSIDRGHARRLAADLAATTGQQVWLAEYRRIPGDPAATLADLRALDALVRATAPVTAWVGHSAGGTLVLWRACAADLPPVPVVALAPVADLRRAAEERLGDGAVVEWMGGTPSDVPERYAAADPLPRLLAGAADRPGGGVTVLHGDLDETVPLRQSAALTGAPGVRVEVLANAHHFDAYDLGAPAGRALVAALRPRGSAARPA
>NZ_CP009896.1|WP_038679096.1|2881570_2882881_+|pyridine-nucleotide-disulfide-oxidoreductase
MPARTRCRDAYGYDLTTGSLAADAYVDGVRDLLRLRSGAASRIATAIALDPTFALGHAALALLGHEMCVEVDVAARLADARLHAGRATERERSHVHAIDRHLQGDPAPLVAHLATYPRDALLLSVAMPTIAFAGVTDVPEQAWRIVEGAAPAYGDDPWIAGILAFVRQEQRRFDEAMDLSCRSLASDPGGGHAAHARAHAHYETGDHAAGLAWMDAWILGDGAATDSLTHFSWHAALHELSIGDLGAVRTRYENQLRPQHAVGCRALVDTGALLFRWAITPDAHDVPALDEVAAVTGRTVLEQPATAFLALHAAVVLLATDDRPGLRRLAEWSAGHASPTHREVVAPLARALDLLAAGRCSQAADRLAALSPQVWRLGGSDAQREIVEEARIAALLRAGRYDDARTVLDARLDRRPALRDLRWKETATAPTGMLVP
>NZ_CP009896.1|WP_052138672.1|2879526_2881533_-|excinuclease-ABC-subunit-UvrC
MSVHLRRVDRVSPALSYRPAPGSIPTQPGVYRFRDRSQRVIYVGKAKNLRARLSSYFQDIGNLHPRTATMVTTATSVEWTVVGTEVEALQLEYSWIKEYDPRFNVKYRDDKSYPWLAVTVSEEFPRVMVGRGAKRKGTRYFGPYGHAWAIRETVDILLRVFPMRSCTNGVFKRSSQIGRPCLLGYIDKCSAPCVGNISPEDHRAIVDDFCEFMAGRTRPFTKRIEQEMYAASDALDFEKAARLRDDLGAMQKALEKQAVVLGDGSDADVIALAEDPLEVAVQVFYVRGGRIRGQRGWVADRTDEGDTSSLVEDFLLQLYAGVAPEDARDAVPREILVPELPPEHATFERLLSDLRGAKVEIRVPQRGDKKSLQETVARNAVESLALHKTKRASDLTTRNRALAEIAEALDLDEAPLRIECYDVSHIQGTEIVASMVVFEDGLARKGEYRRFVIKDQEGSDDVKAMHEVITRRFRRLLDEQARSELRPGDPAAGTGPMLVDPDTGRPRKFAYAPGLVVVDGGAPQVAAAQRALDELGIDDIPICGLAKRLEEVWVPREEDPVILPRTSEGLYLLQRVRDEAHRFAITHHRNRRSKSMVESMLDGVPGLGEVRRKTLLRHFGSLRKLRLATLDEIAAVPGVGPRTAAAIKEAIAADDATRSPSSTGPAPQ
>NZ_CP009896.1|WP_038679093.1|2878652_2879522_-|RNase-adapter-RapZ
MSESTPGQLVVVTGMTGAGRSTAAKELEDLGFYVVDNLPPSLLPDVVRLVDESHGPAQPVAVVVDVRSGSFFQGLRSALAHGVAGRETTLVFLDAIDEVLVRRQEAARRPHPLQEGGRLLDGLHRERVVLADLRSEADLVIDTSNLNVHQLTDRIADAFGTLQTTRLRVSVISFGFKYGIPVDADYVADMRFLPNPHWVPELRPRTGQDPEVAAYVRGRPGAEEFLDAYVPLLAGVAEGYIREGKRFMRVAIGCTGGKHRSVAMSEEIARRFGERGYVARAIHRDLGRE
>NZ_CP009896.1|WP_038679107.1|2890250_2890772_+|NUDIX-domain-containing-protein
MPHPDPATEPVALYGDDGRPTGEVAPRAEVRARNLRHAATLVVVRNSAGEVYVHRRTDTKDVFPGRHDFAAGGVLQAGEIPYDAAVREAFEELGVHGVELTALGEADYSDEHTAYHAFAYTCVYDGPITWQPEEVAWGAWVSVARLREMVGEVEFVPDTVAVLGDWLTGRSCT
>NZ_CP009896.1|WP_052138678.1|2890749_2890929_-|hypothetical-protein
MLSSVEGRQVLWSSLWPARPDDRIELTVIPDPPGPATVGHLRRRLNELLYADLRYSYGQ
>NZ_CP009896.1|WP_038679108.1|2891028_2891640_-|DNA-3-methyladenine-glycosylase-I
MNAALPGPDGLPRCPWSLSPVELPYHDTEWGFPVADDQRLFEKICLEGFQSGLSWRTILVKRPAFRAAFADFDYRVVAGFDEHDVVRLLGDAGIVRHRGKIEATINNAARALETVAEHGSLAAYLWTFETPAAELAAPQTLTTSPAAIALSKDLKKRGWKFVGPTTMFAFMQAMGLLNDHVVGCVTRSEVEAARAAFTPPVAA
>NZ_CP009896.1|WP_038679110.1|2891726_2892074_+|VOC-family-protein
MTLSPAMITLDTTDALALGRWWAERTGGQVVEENDGWFVMVALPDGLRLGFQKVDDPTPGKNRVHVDFVAADLDAAVAELRAAGAGHVGDREMPGFRWVTLSDPDGNEFCVSGAH
>NZ_CP009896.1|WP_038679112.1|2892152_2892542_+|hypothetical-protein
MNLRKHAAVTVAALALGLSAAPVASAVAADAPTKAPCATQQTQLDRAEAKLDALTAKLAAKQAKVREAKGAVKAADAAKEKRSAKATLALAKEKKANVKKAKKAQVQRVAHAQARLDKCTAAHPAAPAA
>NZ_CP009896.1|WP_141267292.1|2892620_2893718_-|ferredoxin--NADP-reductase
MDIESFVLDVVGVVEETADAKSISFAVPEGAEEKFDYKPGQFLTVAVPSDQTGIAARCYSLSSSPHDGGPLTVTVKRTADGYASNWICDNLKVGDTLRALPPSGIFTPASLDADLLLFAGGSGVTPVMSITRTALAHGSGRIVVFYANRDESSVIFAAELTRLAAEHPDRLQVIHWLESVQGLPTEAQMKAFAAAYGGYDSFVCGPAPFMKMVTTVLKELEVPRSLRHQEKFVSLGGNPFGDLAELQEAEAEIALAESDDDGPGADVFADAPAGPVKVEVELDGEEFTFDDWDPRTKLLDFLESKGVKAPYSCREGECSACAIRLLEGDVKMLYNDVLDKDDLDDGIRLGCQSVPLTDTVKITYS
>NZ_CP009896.1|WP_038679114.1|2893742_2894045_-|hypothetical-protein
MASFVPTSDETLEDLRRYTEDRLVDVACLDCLAQVRVKKNSDHQTSVQWSAEARADCQEFQRRGQAPGGRDVHKPCSRLMASIDDAVRAGAVPIGAYDGY
>NZ_CP009896.1|WP_038679116.1|2894055_2895210_-|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MTDTRMLDQGTQPIRFARGWHCLGLASDFADGKPHAVQGFGTKLVVWQGGNGELNVLDGYCRHMGGDLTQGEVKGDHIACPFHDWRWGGDGKCKEIPYARRVPLRARTQRYETVVRNGQLLMWHDPEGSAADHELLPPELPDVMTDKYTPWSWHTKEINGSHCRELIDNVADMAHFYYVHFAFPTSFRNIFDGHTATQFMESKGRPDTMGGGYGDENSTLKSVATYYGPSYMINWLEVDYKGFITEVILINCHIPTGPTSFTLQYGISVRKPEGLDEKTCAYIAERYTESFGDGFLQDVAIWENKVAVQNPLLCEEDGPVYQLRRWYEQFYVDVADIAPEMTDRFEFEVDTTKANEYWHAEVADNLAKRAAAEADAEAAAPADA
>NZ_CP009896.1|WP_038679118.1|2895282_2896473_+|acyl-CoA-dehydrogenase
MHIDLEPQQVALREELRAYFAQLVTPEIRAGLASATGEFGEAGVYKDVIRQIGKDGWLGIGWPKEYGGQARSMVEQLIFTDVAAIAGVPIPYLTLNTVGPTIMRFGSDEQKEFFLPKILAGELHFSIGYSEPGSGTDLASLQTKATLEGDEWVINGQKMWTSLIQYADWLWMACRTEPDAPRHKGLSMILVPADAPGVSYTPVHTVAGVGTSATYYSDVRVPATNLISERGGGWALMTNQLNHERVALTSAAPLVHSLQLVKDWAAETRNPDGTRVIDTEWVQIALGRAHARVEALSLINWKLAADADHGVALSPAEASATKIYGSELATEVYRSLMEVVGPHAGITADSPGAVLAGRLERFHRSSLVMTFGGGTNEIQRDIIGYVGLGLPAAKRA
>NZ_CP009896.1|WP_038679120.1|2896490_2897516_+|acyl-CoA-dehydrogenase
MDFLFTPEQDEAAELAAQILKDKTTNARLKEVEAGGDRFDRELWATLGDAFDWTELDLVTLARVLVEVGRHVAPLPLATHTACTTLVTGAGQDAGQGLYAAAVAEERSHLPASPAVTADATGGDYWSVTGTKTLVRAGMAADLLLVTATGPDGPGVYLVDVTADGVERVAQKTSDGDVAALITFANAAGVRIGGPDSAERLGQLLVALAAAEQLGVTEGALRLTSEYAKTREQFGRPIGTFQAVSQRLADGFIDVLGQRLTLWQAIWRLDEGLPAGTEVATAKLWAADAGHRIAHTTVHVHGGVGIDLDGEAHRYFTSGKRFEFLFGGATEQALAIGRSFA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_8

3217568-3217656

Orphan

Consensus_repeat	Method
GAGTTTCGCCGGTCGACCGGCGAAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_8

>merge|NZ_CP009896|8|3217568-3217656|CRISPRCasFinder
GAGTTTCGCCGGTCGACCGGCGAAACTGGCTCTTGACCGACGGAACTTCATCGGTCAAGTGTGAGTTTCGCCGGTCGACCGGCGAAACT

>NZ_CP009896|8|8|3217568-3217656|CRISPRCasFinder
GAGTTTCGCCGGTCGACCGGCGAAACT	GGCTCTTGACCGACGGAACTTCATCGGTCAAGTGT
GAGTTTCGCCGGTCGACCGGCGAAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038679633.1\|3214725_3215355_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP009896.1\|WP_038679647.1\|3222873_3223359_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380340
NZ_CP009896.1\|WP_038679639.1\|3216853_3217195_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227936
NZ_CP009896.1\|WP_038679626.1\|3212217_3212682_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|182510
NZ_CP009896.1\|WP_082003687.1\|3223238_3224261_+\|acyl-CoA-thioesterase-II	unknown	unknown	gnl\|CDD\|224857
NZ_CP009896.1\|WP_038679645.1\|3222005_3222884_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP009896.1\|WP_082003688.1\|3226602_3227016_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_CP009896.1\|WP_052138748.1\|3217674_3218673_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_CP009896.1\|WP_052138746.1\|3213700_3214183_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038684605.1\|3218802_3219282_+\|flavin-reductase-family-protein	unknown	unknown	gnl\|CDD\|214900
NZ_CP009896.1\|WP_038684599.1\|3210785_3212105_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|379134
NZ_CP009896.1\|WP_052138750.1\|3220424_3221387_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|373110
NZ_CP009896.1\|WP_038684607.1\|3221481_3221913_-\|RidA-family-protein	unknown	unknown	gnl\|CDD\|100004
NZ_CP009896.1\|WP_038679637.1\|3216024_3216822_+\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|377028
NZ_CP009896.1\|WP_038679628.1\|3212946_3213657_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133400
NZ_CP009896.1\|WP_052138747.1\|3217205_3217529_-\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NZ_CP009896.1\|WP_038679650.1\|3224257_3226615_+\|bifunctional-salicylyl-CoA-5-hydroxylase/oxidoreductase	unknown	unknown	gnl\|CDD\|236203
NZ_CP009896.1\|WP_038679635.1\|3215351_3216014_+\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|119339
NZ_CP009896.1\|WP_038679641.1\|3219312_3220428_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|238527
NZ_CP009896.1\|WP_038679631.1\|3214247_3214502_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038679633.1\|3214725_3215355_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.21206e-06
NZ_CP009896.1\|WP_038679647.1\|3222873_3223359_+\|cupin-domain-containing-protein	gnl\|CDD\|380340	cd02210, cupin_BLR2406-like, Bradyrhizobium japonicum BLR2406 and related proteins, cupin domain. This family includes bacterial and fungal proteins homologous to BLR2406, a Bradyrhizobium japonicum protein of unknown function with a cupin beta barrel domain. Proteins in this subfamily appear to align closest to RmlC carbohydrate epimerase which is involved in dTDP-L-rhamnose production, and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	5.32149e-33
NZ_CP009896.1\|WP_038679639.1\|3216853_3217195_-\|hypothetical-protein	gnl\|CDD\|227936	COG5649, COG5649, Uncharacterized conserved protein [Function unknown].	6.65781e-40
NZ_CP009896.1\|WP_038679626.1\|3212217_3212682_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|182510	PRK10514, PRK10514, putative acetyltransferase; Provisional.	3.67578e-47
NZ_CP009896.1\|WP_082003687.1\|3223238_3224261_+\|acyl-CoA-thioesterase-II	gnl\|CDD\|224857	COG1946, TesB, Acyl-CoA thioesterase [Lipid metabolism].	1.47353e-76
NZ_CP009896.1\|WP_082003688.1\|3226602_3227016_+\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	1.41609e-22
NZ_CP009896.1\|WP_052138748.1\|3217674_3218673_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	9.68735e-20
NZ_CP009896.1\|WP_038679645.1\|3222005_3222884_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	5.63207e-87
NZ_CP009896.1\|WP_038679641.1\|3219312_3220428_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|238527	cd01094, Alkanesulfonate_monoxygenase, Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin mononucleotide (FMNH2), which is provided by the NADPH-dependent FMN oxidoreductase (SsuE).	6.32032e-70
NZ_CP009896.1\|WP_038684599.1\|3210785_3212105_-\|MFS-transporter	gnl\|CDD\|379134	pfam13347, MFS_2, MFS/sugar transport protein. This family is part of the major facilitator superfamily of membrane transport proteins.	5.00281e-68
NZ_CP009896.1\|WP_052138750.1\|3220424_3221387_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|373110	pfam14525, AraC_binding_2, AraC-binding-like domain. This domain is related to the AraC ligand binding domain pfam02311.	1.16039e-30
NZ_CP009896.1\|WP_038684607.1\|3221481_3221913_-\|RidA-family-protein	gnl\|CDD\|100004	cd00448, YjgF_YER057c_UK114_family, YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	3.74249e-28
NZ_CP009896.1\|WP_038679637.1\|3216024_3216822_+\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	1.78964e-06
NZ_CP009896.1\|WP_038679628.1\|3212946_3213657_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133400	cd04773, HTH_TioE_rpt2, Second Helix-Turn-Helix DNA binding domain of the regulatory protein TioE. Putative helix-turn-helix (HTH) regulatory protein, TioE, and related proteins. TioE is part of the thiocoraline gene cluster, which is involved in the biosynthesis of the antitumor thiocoraline from the marine actinomycete, Micromonospora. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Proteins in this family are unique within the MerR superfamily in that they are composed of just two adjacent MerR-like N-terminal domains; this CD mainly contains the C-terminal or second repeat (rpt2) of these tandem MerR-like domain proteins.	9.7748e-22
NZ_CP009896.1\|WP_052138747.1\|3217205_3217529_-\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	0.000134023
NZ_CP009896.1\|WP_038684605.1\|3218802_3219282_+\|flavin-reductase-family-protein	gnl\|CDD\|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	3.04107e-35
NZ_CP009896.1\|WP_038679635.1\|3215351_3216014_+\|enoyl-CoA-hydratase	gnl\|CDD\|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	6.56094e-43
NZ_CP009896.1\|WP_038679650.1\|3224257_3226615_+\|bifunctional-salicylyl-CoA-5-hydroxylase/oxidoreductase	gnl\|CDD\|236203	PRK08255, PRK08255, bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase.	0

>NZ_CP009896.1|WP_052138747.1|3217205_3217529_-|GatB/YqeY-domain-containing-protein
MSDLADRLRADLTTALRARDRTRASVLRTVLGAIANAEAVPVPQAAPPLAEGVIAGAVVGLGAAEVPRRDLGEDDVRAIVVAERDDLLAHGMTAEAALLAEYLSVAE
>NZ_CP009896.1|WP_038679639.1|3216853_3217195_-|hypothetical-protein
MSADWRSDLVDELRTLIVQAEPDVVEEAKWKKASNPDGVPTFSADGLICTVETYKDKVKVTFAKGAALGDPTGLFNASLDAGTRRAVDVFEGEQLDGDAFVALVREAVALNRS
>NZ_CP009896.1|WP_038679637.1|3216024_3216822_+|endonuclease/exonuclease/phosphatase-family-protein
MHIVSVNAWGGARFDDLAAWLPASKADVVCLQEVTRTADLGGWTSFEDADRSLPQRANLYDDVRALLPDHTALFVASDAGPVTDAHGRRHHQDFGLGTFVAPQVPLLGTAEGFVHGEFTDHDEWAVSERPRAVQGLRVADPVVPGRTVCVVQLHGLRDSAGKGDTPARQAQAERLAAFVEDTRADGDLVVVAGDLNLLPDSATFGVLREVGLIDLVGTADTRTAAYPKPVRHAGYLLVSDPGAVVDFAVLEAPEVSDHRILALTL
>NZ_CP009896.1|WP_038679635.1|3215351_3216014_+|enoyl-CoA-hydratase
MSILTEHDGVHVLTIGATENRFTADLLTAIDEALDHVEAAPAPLVTVAEGKFFSNGLDLDWVLANPDELGPYSARVEALLARFLTLPVPTVAAVNGHAFGAGAMLAMAHDWRVMRADRGYFCFPEVDIRIPFTPGMAALIQAKLTPRAALDSMATGRRYGGAEAEAIGLVDATATDDRLLADAVARVAPLAGKDAPTLGAIKSTMYADAARALRHEQPQT
>NZ_CP009896.1|WP_038679633.1|3214725_3215355_+|TetR/AcrR-family-transcriptional-regulator
MPRQRLHSVDDLLDVAEQLVTSGDPAGLTLRALAASAGASNGTIYHAFGSREELLARLWLRATDRLGSLLSVATEATAGVEAVVAAALAPVRFTRAHPASAQLFFAQRSDQLFTADLPRALTDALAADRRQLTALLARLADGVWGRHDRHAVAAVATCVVDVPGGVVRRALLEHRAVDAAAERRIEAAVRAILALPLDPPPTRTQRRHP
>NZ_CP009896.1|WP_038679631.1|3214247_3214502_+|hypothetical-protein
MSTADRPDQRDDRALLAACQQEVSAARERLEDARRRGARQEVEPLRDSLIAALEGYAAVIERTGAPLPQRLQGELRLYRGLGRH
>NZ_CP009896.1|WP_052138746.1|3213700_3214183_+|hypothetical-protein
MDQILQTLRSLDGVLELAPGPGSAFPELAWGDHFFYYAPDGRLPEREQPFATVVTKDYPDDTGSALDPPGRWRLNIHAGRGALAALASDPDRADPTDHAAADVVLPHPVYGAQGWVAVVNPGERTRSLVARLLRQAHADAVRRTERRPRIPLPDPAGGVE
>NZ_CP009896.1|WP_038679628.1|3212946_3213657_-|MerR-family-transcriptional-regulator
MADLTTAAVAAASGYSVQQVRDLEARGVIAPAARAANGYRRFTADHVQDLHAYRDLAAAVGPVEARRALREVRRLPAGAATELVGRLHAGLVAEREQALAARAALTAIGAEPGTDAPPVPADTMTITELAQALGVKASTLRFWEQAGLVAPERVATRAGTARRYPVPAVREARIAAALRAGGYRIPDVRRAIAAVRDLEDVSDSVAALDARLDAIAGRALALLRAGARLAGIIAAP
>NZ_CP009896.1|WP_038679626.1|3212217_3212682_+|GNAT-family-N-acetyltransferase
MTAELRIRPTAGPAEHPALVAIWRSAVQATHDFLAPADFARIEGALATDYLPAVTLVVAERDGVAVGFAGVHDGSLEMLFVSDDARGGGVGSALLSEVIAAHGVTRVDVNEQNPGALGFYEHRGFRVTGRSPLDGDGRPYPIVHLELAEPAPTS
>NZ_CP009896.1|WP_038684599.1|3210785_3212105_-|MFS-transporter
MSDELPARIRRGYALGGVASGVYGTVPSLLLMPYLTEELGVGALLAGLVVFAPKAWDFVCNPLAGRVSDRVRRHDRRRPFLLVAGPLMGVGLAFVFTGPSTPFLLALAWVLVANLAAATAYAFFQVPYLAMSAEVTGDYGVRTQMMAWRVGVVTSAIAVSGVVAPWLATTAGGYRAMGVLSGLVVVGGSLAVWWCTRGAPVVRAEAAGGGLRDQLRVVLGDVHARPLVAALVLQAAGTSMLLAAVAYAARVLLGDAATGSYLFGAFVVPGVLSAPLWAWVGRRHGKRGGYVIATAVLGCGLVAMVGVWTGSLAWCLVWAAVTGAGYAGIQVFPLAMLPDVAAHDARTTGRNRIGLFSGVWAGCELLGFALGPGLLGVVLALGGYEGGQDSYGTAARLAVLAGTSVVPAALVLLSLLAIRAYRLDDALRTPSPVESATAS
>NZ_CP009896.1|WP_052138748.1|3217674_3218673_-|AraC-family-transcriptional-regulator
MAGTVMPLGSYGVLRTTDVDDARASIAASLAPHRLTPLAGAGGFRALHNAAHLGRLSVHYIDYGAEVEVAVDGMDFQLVQIPLAGRTTISCGREHVVATQRTAAVTAVGESVRMRYSAGNPRLMVRIGAALLHDRLALAERVGAVPSPAPGVAATFDLTQGRGRSWRGMLDVLLADLERESGLTAVPLAAGALEVALVDGLIASLAADPAGAGAAAGAAGPVTTPHERVVKRAAQLIEDHCAEPLGTADVAEAVGLSVRVLRAGFQEHFATTPMAYLRHARLRRVRDDLSDGTAASVTEAALRWGVTHLGRLSGDYRAIFGETPSETLQRAR
>NZ_CP009896.1|WP_038684605.1|3218802_3219282_+|flavin-reductase-family-protein
MTCVTPTTAEVSPAMLREQLARWPTGVAVVTATGRDGRPIGKTVNSFHATSLAPPLVGWCIDHRSSQVDDWLAAPGYVVHVVAAHQGPLMRHFATPSADRFAGVAWQPGLDGMPVLDEPVALRLECRAAHRFAAGDHTYLVGEVVILTAADAVPLCLQR
>NZ_CP009896.1|WP_038679641.1|3219312_3220428_+|LLM-class-flavin-dependent-oxidoreductase
MTIPIVEADHFRLGLFSSNCSGGLAVTTIPERWSASWEDNLALARLADEVGIDFMLPIARWIGYGGTTNFHESVLEPIPWATAILAHTERLTAFATVHTAFNHPVVTAKQLATIDQMAPGRVGVNVVAGWNQPEYEAMGVDLPQDHDSRYALAQEWVDALGTLWSREGRYDLPGRFWDLKGVEAEPKPAAGRLPILNAGSSTQGRAYAARNADFVFTIVGGPEDGADVVTQVRAEASVQGRTSGVLTPTHVVCRPTRAEAEEFLHYYAVENADWDAVDNLMRLQGLHAQSFTPEMLAGFRSRFAAGHGTCPLIGTPDDVADEIERFAKAGFGGITMAFVDYVGELDYFAQEVMPRLVDKGLRPELAHEKTT
>NZ_CP009896.1|WP_052138750.1|3220424_3221387_-|AraC-family-transcriptional-regulator
MPTTLLSRHPQIATADPEQARDEVARRFCPHRLELTRRTGRLDMLHNAAAIGPDVTLNYLRYGDEVRITPGRFDDFFLVQVPISGSARVKVGDRVVASDRVRGSLGSPTEPVDMVWSDGCEQLLVYLRRQAVEELAGGADDPRPVVFDPSMYLETPSLRAWLRLVHLALDDIEAGGALFRSPLAATHFEQTLISGLLAAQPNSSNEAPREPAAGSRVVRTVMGLIDAEPERAWRLAELAGEAGVSARTLQEAFQRELGSSPLEQLRRTRMERARRDLVEADPVHTSVTDIAARWGFFHLGRFSQSYRAMYQELPSQTLAG
>NZ_CP009896.1|WP_038684607.1|3221481_3221913_-|RidA-family-protein
MSIDLTPLAVNPAALPVPSGFSHGTLSGNTLYLGGQTALDKEMRIVPGGIVEQFRQAFGNVLATVREAGGVPEDLVSITIFLTDIPDYQAHGREIGRVWRELAGPVYPAMAGIGTTGLWQPEALIEIMGVAVIPDERLVRPAS
>NZ_CP009896.1|WP_038679645.1|3222005_3222884_+|fumarylacetoacetate-hydrolase-family-protein
MRLATVTTPGGTTAALLGEHGWRALPAPDLSALLAAAEADGGWDPARVAAQADELDRDLPGAVPVLALPRPGKVICCGLNYGEHIQETGRDLPTHPTLFAKFADTLTGPDDDLALADGVQWDWEAELAVVVGRTLRRAGRDEARAAIAGYTVANDLSARDWQYRTLQWLQGKAWDATTPVGPVVVTPDEVDPFAGVDVVCRVNGEEVQRDSTRTLVFDCADLLAYVSTFATLRPGDLVLTGTPGGVGVARDPKRFLADGDVLETEVAGIGTLRNTVRLTPLTTLSQEHPHGA
>NZ_CP009896.1|WP_038679647.1|3222873_3223359_+|cupin-domain-containing-protein
MEPDLSKYELIGDNSVYANESGIVVPVVTRAGFEPDLTGQSEGATRVSGVSIQHTPATRIWFGKVHNLAGYRSVPHHHGEAETGGYVLSGRARIYFGEKFEDYIDMSEGDWVFVPPFMPHVECNLDRNNPLTWMTTRTPENIVVNLAQVTDGELPDWTDRP
>NZ_CP009896.1|WP_082003687.1|3223238_3224261_+|acyl-CoA-thioesterase-II
MQPRPQQPAHLDDHPHPREHRRQPRPGHRRRAARLDGPAVNPTSQIFTDAVTLKECPAEVFDHAFTATTQPCPWPKAYGGDMVAQALVAASRTVGDGKSMHSMHSYFMRPVDIGAEVRYEVEALRDGRGYSTRQVRGFQNGKPVYVCLASFAAGEPSGSFQAEMPAGLPGPDTLPTSAAYLADRSGGTMTDVSKDYWQHGRSFDMRHVPGPVYLTVEGERTPHQAIWVRPYDALRDVEGLTAEQRDAAALAYVCDYTILEPALRVLGLAWADEGLVTASLDHAMWFHRPVRMDDWLLYAQEAVSVDDGRGMAVGRFFTPDGVLVASVVQEGMIRAGGRSS
>NZ_CP009896.1|WP_038679650.1|3224257_3226615_+|bifunctional-salicylyl-CoA-5-hydroxylase/oxidoreductase
MRIAIAGGGPGGLYFAALMKQLDPAHEVTVWERNAPEDTFGFGVVFSDETLGSIEGADQVVHDRMESRFARWTDIDVDVDGRSYTIGGQGFAAMSRKELLQILQERVAELDVTVHYRTEAPDVDELRASYDLVLAADGLNSSIRTKHADVFGPSLDRRHNKYIWLGTDLVFEAFQFFVKQTEWGTMQIHGYPYSAEGSTFIVEMHEDVWRRAGFDATEHEVFPPGVSDEHAVAKVKEIFARELQGHEVLTNNSKWLSFHTVRNERWHHDNVVLLGDAAHTAHFSIGSGTKLAMEDALALAACLHEHPTVPAALEAYQTERKPVVESTQRAAQASLEWFENIGMYADQDPTAFVFNLLTRSRRITFDNLKDRDPGFAGVVEDAFARTYGDGSPGPAMFQPTRIGPLELANRIVLSPMDMYSAVDGMPSDFHLVHLGSKAMGGAGLVMTEMTCVSPEGRITPGCPGLWNDEQRDGWARITSFVHERSRGKIGVQIGHSGRKGSTKLMWEGMDEPLDDGNWEVLGPSPLPYGPTCHVPREATRADLDQVVADFVATARRAVEAGFDLIEVHAAHGYLLSSFLSPVSNRRTDDYGGSLANRLRFPLEVFDAVRAVVPESIPVTVRISAHDWLPDGNTDDDAVEIARAFIEHGAAAIDVSSGQVSKDEKPAFGRSYQTPFADRIRHEVAAPAGVAVIAVGAISSYDDVNSILLAGRADLCALGRTHLYDPSWTLHAAAEQDYRGPGATWPVPWQAGRRKPPTSRTDKIPPRLSLLRDGDGDGLVHVRWTP
>NZ_CP009896.1|WP_082003688.1|3226602_3227016_+|acyl-CoA-thioesterase
MDAVTVQATHRGRVEWIDTDSAGIHHNTAIARYVESAEAALMRGLGLDAYFASAPRVRYEVDFEAPLRFGDEVTATVQVERVGTSALSLTFEVHGGPEGTAPVRVARGRYVTVHIDRATGTSSPWPDDWRAALGAAD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_9

3489911-3490038

Orphan

Consensus_repeat	Method
CGGCCGGCAGCGTGGCGGGAGGCCGTCCTCGGGCAGCTTGCTGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_9

>merge|NZ_CP009896|9|3489911-3490038|CRISPRCasFinder
CGGCCGGCAGCGTGGCGGGAGGCCGTCCTCGGGCAGCTTGCTGCCGGTTCGAACGGCCGCAGACACGCTCGGCCCCGACGAACCGGCCGGCAGCGTGGCGGGAGGCCGTGCTCGGGCAGCTTGCTGCC

>NZ_CP009896|9|9|3489911-3490038|CRISPRCasFinder
CGGCCGGCAGCGTGGCGGGAGGCCGTCCTCGGGCAGCTTGCTGCC	GGTTCGAACGGCCGCAGACACGCTCGGCCCCGACGAAC
CGGCCGGCAGCGTGGCGGGAGGCCGTGCTCGGGCAGCTTGCTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_052138803.1\|3497385_3498357_+\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|238958
NZ_CP009896.1\|WP_038679970.1\|3497146_3497389_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237001
NZ_CP009896.1\|WP_052139338.1\|3486211_3487126_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP009896.1\|WP_038679968.1\|3495759_3496146_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_082003698.1\|3492922_3495781_+\|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	unknown	unknown	gnl\|CDD\|236500
NZ_CP009896.1\|WP_038679950.1\|3481518_3481881_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377164
NZ_CP009896.1\|WP_038679972.1\|3498353_3499346_+\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP009896.1\|WP_082003982.1\|3492365_3492743_-\|DUF3052-domain-containing-protein	unknown	unknown	gnl\|CDD\|378615
NZ_CP009896.1\|WP_052138804.1\|3499342_3500728_+\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223239
NZ_CP009896.1\|WP_052138800.1\|3487196_3487583_+\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NZ_CP009896.1\|WP_038679962.1\|3489072_3489909_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|375319
NZ_CP009896.1\|WP_038679956.1\|3484872_3485319_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_141267737.1\|3483994_3484861_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP009896.1\|WP_038679952.1\|3483312_3483987_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP009896.1\|WP_038684742.1\|3490214_3490679_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|239316
NZ_CP009896.1\|WP_052139340.1\|3487536_3488970_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP009896.1\|WP_052138802.1\|3496286_3496991_-\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
NZ_CP009896.1\|WP_141267735.1\|3485444_3486077_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_082003697.1\|3481762_3483328_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP009896.1\|WP_038679964.1\|3490711_3492355_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236097

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_052139340.1\|3487536_3488970_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.5881e-42
NZ_CP009896.1\|WP_038679972.1\|3498353_3499346_+\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	1.3735e-104
NZ_CP009896.1\|WP_052139338.1\|3486211_3487126_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.76605e-40
NZ_CP009896.1\|WP_052138803.1\|3497385_3498357_+\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	gnl\|CDD\|238958	cd02000, TPP_E1_PDC_ADC_BCADC, Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain alpha-keto acid dehydrogenase/2-oxoisovalerate dehydrogenase complex (BCADC). PDC catalyzes the irreversible oxidative decarboxylation of pyruvate to produce acetyl-CoA in the bridging step between glycolysis and the citric acid cycle. ADC participates in the breakdown of acetoin while BCADC participates in the breakdown of branched chain amino acids. BCADC catalyzes the oxidative decarboxylation of 4-methyl-2-oxopentanoate, 3-methyl-2-oxopentanoate and 3-methyl-2-oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine).	3.60695e-85
NZ_CP009896.1\|WP_082003698.1\|3492922_3495781_+\|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	gnl\|CDD\|236500	PRK09405, aceE, pyruvate dehydrogenase subunit E1; Reviewed.	0
NZ_CP009896.1\|WP_038679950.1\|3481518_3481881_+\|hypothetical-protein	gnl\|CDD\|377164	pfam03929, PepSY_TM, PepSY-associated TM region. The PepSY_TM family is so named because it is an alignment of up to five transmembranes helices found in bacterial species some of which carry a nested PepSY domain, pfam03413.	2.41077e-05
NZ_CP009896.1\|WP_052138804.1\|3499342_3500728_+\|aspartate-aminotransferase-family-protein	gnl\|CDD\|223239	COG0161, BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism].	1.16286e-177
NZ_CP009896.1\|WP_038679964.1\|3490711_3492355_-\|AMP-binding-protein	gnl\|CDD\|236097	PRK07788, PRK07788, acyl-CoA synthetase; Validated.	0
NZ_CP009896.1\|WP_038679962.1\|3489072_3489909_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	4.36682e-51
NZ_CP009896.1\|WP_141267737.1\|3483994_3484861_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.84042e-50
NZ_CP009896.1\|WP_038679952.1\|3483312_3483987_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	8.00932e-83
NZ_CP009896.1\|WP_038684742.1\|3490214_3490679_-\|peroxiredoxin	gnl\|CDD\|239316	cd03018, PRX_AhpE_like, Peroxiredoxin (PRX) family, AhpE-like subfamily; composed of proteins similar to Mycobacterium tuberculosis AhpE. AhpE is described as a 1-cys PRX because of the absence of a resolving cysteine. The structure and sequence of AhpE, however, show greater similarity to 2-cys PRXs than 1-cys PRXs. PRXs are thiol-specific antioxidant (TSA) proteins that confer a protective role in cells through their peroxidase activity in which hydrogen peroxide, peroxynitrate, and organic hydroperoxides are reduced and detoxified using reducing equivalents derived from either thioredoxin, glutathione, trypanothione and AhpF. The first step of catalysis is the nucleophilic attack by the peroxidatic cysteine on the peroxide leading to the formation of a cysteine sulfenic acid intermediate. The absence of a resolving cysteine suggests that functional AhpE is regenerated by an external reductant. The solution behavior and crystal structure of AhpE show that it forms dimers and octamers.	3.82928e-64
NZ_CP009896.1\|WP_082003982.1\|3492365_3492743_-\|DUF3052-domain-containing-protein	gnl\|CDD\|378615	pfam11253, DUF3052, Protein of unknown function (DUF3052). This family of proteins with unknown function appears to be restricted to Actinobacteria.	5.46652e-57
NZ_CP009896.1\|WP_052138802.1\|3496286_3496991_-\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	1.62865e-38
NZ_CP009896.1\|WP_052138800.1\|3487196_3487583_+\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	8.31118e-09
NZ_CP009896.1\|WP_082003697.1\|3481762_3483328_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.7081e-52
NZ_CP009896.1\|WP_038679970.1\|3497146_3497389_+\|hypothetical-protein	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	4.54417e-21

>NZ_CP009896.1|WP_038679962.1|3489072_3489909_+|helix-turn-helix-domain-containing-protein
MPPPVTELGEFLRSRRDRLTPDEVGVRTYGRRRVPGLRREELAQLAGVSVTYLTRLEQGQSTNASDAVVDALARALRLDPDERAHLFALARPAPVRRPRSPRPESASPGAEQLLHAMGDVPALLLGRVNDVLAWNRAGHRLLAGHLDPTAPSRPADRPNQFRLLFLDPHTRDLYADWRAEAALAVASLRYVAAHHADDRRLAELVGELSVRSPDFAALWAGHAVALCTSGTKRFRHPEVGALDLDYEVLHLPDGNGQRILTHTAAPGSPSDAALRLLR
>NZ_CP009896.1|WP_052139340.1|3487536_3488970_-|MFS-transporter
MSQLELDPVRRRPTGPARSERIALAVLLTANFTLAVDFSILNVALPHIGRELGFATADLQWIVTAFALCAAGFTLFFGRVADLFGRRRLFLAGMVLLGVSSLAGGLAGEPALLIGARIGQGLATAMVTPAALALLTTIFPEGPARARALGLNGALMAAGFTTGAVLGGVLTGVVSWRWAFFVNVAVAVVVVAVGPAVLRATPAGRRPRLDAPGAVTVTLALVALVLGIDGAGRSGWTDAAAWGPLLAAVALLVVFGAVEARVAEPLVPPALLRRRTVTWANLAGLLAFATETSLVFLLTLYLQETLGFSAVTAGLVLAVLGVGTVLGGLLAPRVIARTGGPVAIVGGLVVQAAATLPLVLLGPDRGWLVLLLVASFVGGVANLVAIVGYAVTATAGVPEDQQGLATGLVTMSQQVGITLGTPVMSALATGFASASLLPGLRVAIGVDAVLALLTAAAVAVALVSRPARRRASVAGRR
>NZ_CP009896.1|WP_052138800.1|3487196_3487583_+|nuclear-transport-factor-2-family-protein
MTDPLPTDSLPADPRAIAERYFACWAAGDPEPLRPLLSPTVTFDGALGSTRGADEFVAGLAGMFAATTANDVLLRLADDHDVVTWSALRIAGKPPLQVANWTHVEDGLITAVRVTFDPRPMLGDAPAG
>NZ_CP009896.1|WP_052139338.1|3486211_3487126_-|LysR-family-transcriptional-regulator
MELHQLRYVLEVHRRGSFTGAAEALHVSQSGVSAQVAKLERELGVRLFERGSRLATLTPDGVALLPHATAALDAVGRVRAVADDLSGVVRGQVRIGTVIGCTIPGYLAGFAAFRAAHPGVAVTASEGSSADLVTALTDGDLDLALVAHAGPLPPGLDVVTVVDELLVAGVPAGHPWSVRTALAPAELAASDVAVLTLPPGTGIRAALDRTCADAGVTLTPAVQVHSPEAALALAAQGAGVAVLAASMVGAPLRAVPLAGSVTTALSLATRAEPGAAARAFAGLLRDRLVGGVGATGIEPVTTSL
>NZ_CP009896.1|WP_141267735.1|3485444_3486077_-|hypothetical-protein
MHLMTSVRRTVAALTLSTALVAGTAALAAPAHAERWTHDDAVGDVVRETMGEPGAELTPAPERTSIDITRVVANHKGRNLTIKVRTRSAMKGVLMSTSTIRTPSKRLMLMSSRIPMFGSSLDLYDINTKRRDPSVRCPGLKRTFDKSRTVMTTTIPRSCLGNPRWVRFSVDLATADLLADDDYSYQEDGLRDGSGSGFGPRKMSPKIKHG
>NZ_CP009896.1|WP_038679956.1|3484872_3485319_-|hypothetical-protein
MKKKPVVAAATGLVGLMASGLTISLLAWPADAGSASGSDGNLAVKREEDTPDVVLVVDDDDDDPADALRARQGADTNTNTRATRTRATQATKATGNSRDNTRTGARSGRDDSRSGRAVRDWTQDGPGPKVRDWSRNHTNDRSRHNTRG
>NZ_CP009896.1|WP_141267737.1|3483994_3484861_-|protein-kinase
MSSWHFAEGDAITPELTALRLLGGGSAYEAYLAFDEITYGPVVAKVVRPAEADDEHTVRSLVREATALDVAHHPVVVRGLRHDAEGPRPHLVLEHVEGPSLSRLIRRHRRLSPQQYLPLAIDLASALHFFRHADVCHLDLKPSNVIMGAPARMIDLSVARPDDQAAALTTPIGTDAYLAPEQAAPGTAYGVPGYASDVWGLGTTLFHAVAGVRAFRPGDPDAADPAARFPQLLDAPAELPDDVPAVVAKTIHAMLELDPADRPLPREVAEALEPELAGLPAPRLHWKG
>NZ_CP009896.1|WP_038679952.1|3483312_3483987_+|response-regulator-transcription-factor
MARILIVEDEERIASFVAKGLRAEGHQTTVAGDGLTGLDHALSGDFDLLVLDIGLPRLDGFAVLDQLRAQGSRMPVIVLTARDSVTDTVTALEGGADDYMPKPFRFAELNARVKLRLRRLAPADGGAEALDHLTTGSVRLDLRTRRATVAGREVELSAREFALAEIFLRHPGQVLSREQLLDHVWGLDFDPGSNVVDVYVGYLRRKLGADTIATVRGMGYRLDR
>NZ_CP009896.1|WP_082003697.1|3481762_3483328_+|HAMP-domain-containing-histidine-kinase
MTTATTTATTAGAATAAATTTGTGTTGTTGTTTTSPMTTERRPGLSVRTRLTAAVALLVTVALAGAGLIVYWVESRSLDEATQRGVEQELDEFVALQRSGDFASVRDLLSGFLQRNVPDEDELLVGWVGDGTIVRFPDDPLVRDRRFLDAVTPLVTDGGTAYLDTDRGEVRITSQPVSQGSQRGALLVVTYLDEERGELLRTMRTYAVVGLLSAVLVTAVAAWQSGRLLRPLRALRLATERTSAADLSRRLPERGNDDITALTRTVNGMLDRLEHAFAGQRQFLDDAGHELRTPLTVLRGHLELLDAGDPAEVAETRDLLLDEVDRMARLVGELILLAKSDRPDFLSPATTDVAALLAAVVTKARGLGDRDWALALADGLPDDLVLDAQRITQALLALADNAVKHTGPGARIEIGAAVVGSTLRCWVHDAGPGVAPDDRERIFQRFGRAAVPDGDEGFGLGLSIVAAIAEAHGGRAYVDPAPARGARFVVDLPAVRAATTERPPPTATTSATTEEHPWPAS
>NZ_CP009896.1|WP_038679950.1|3481518_3481881_+|hypothetical-protein
MGRVGKVLLPLALLLAITGFAAGAVVAAGADDDPPARPPVELPAVPTTPTSPTTPTAPPTRTPAAPPTSDDVIRPQPDLDDDDDRDDDRDDRRGRDRGSDDDRDRDDRDDRDDHDEPDDD
>NZ_CP009896.1|WP_038684742.1|3490214_3490679_-|peroxiredoxin
MGIELGGLAPDFTLRDQFGQDTTLSSYRGVKAVALVFYPFAFSGVCTGEMNAFRTRLDEFLTFDTEVLAISCDPVYALRAFSDADGLNFPLLSDFWPHGEVARAYGVFDERGGSAERSSYVIDRAGRLSWAVHHPKPAARSADELLEALRYASA
>NZ_CP009896.1|WP_038679964.1|3490711_3492355_-|AMP-binding-protein
MGKIASRVTGKVKDTGTSLKILTESGIVRPYSPSVLAGMANALRQWSTTPAGGFKTIALRMPEQTAIIDERGALTFGELQERTNALAHGLRDRGVRPGDGVAVMCRNHRGFIEASIAISKLGADVLYLNTAFAGPQLADVLEREKPRVVVHDEEFTGLLSGADLRDRVLGWTDGEPGDDSLEGLIAAGLAAGRTDDLAPPASKGRTIILTSGTTGTPKGAPRPQGGLPAAISLLSRMPLRSGWKCHVAAPLFHTWGFAHYQLAMMLGTTLVLTRKFDPEDALRILRDEDCDSFAVIPVMLQRILALPDETLDKYPLPNLKAVASSGSALPGDLPTRWMDRYGENLYSIYGSTEVAWASIASPDDLRKAPGTAGRLPHQTVVRILDEAGREVPQGESGRIFVGNSLQIEGYTGGGGKEMVDGLMSSGDVGRFDAEGRLYVEGRDDEMIVSGGENVFPKEVEDCLAGHERVAEVAAIGVEDPDFGKRLRAFVVRVPDGEPVSADELKDLVKQNLARYKVPREIVFLDELPRNATGKVLKRELAAIEPGE
>NZ_CP009896.1|WP_082003982.1|3492365_3492743_-|DUF3052-domain-containing-protein
MGLKPGMVVQELGWDNDTDDALRVALEDAIDGDMVDGDYGNVVDAVLLWWREDDGDLVDGLVDALTDLVGGGVIWLLTPKIGRPGAVDAADIAEAAPVAGLAQTTAATVSKDWAATRLVAPKSIA
>NZ_CP009896.1|WP_082003698.1|3492922_3495781_+|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type
MGRFSALEGGATMGSVTSDTNPGGPTPAARAGSAPSVIHEGLPTQLPDIDPDETQDWIDSFNALVDERGRERARYVMLRLLERAREAQVGVPALRSTDYINTIPPEREPWFPGDEDVERRIRAFIRWNAAVMVSSANRKGLEVGGHIATYQSSASLYEVGFNHFFRGKEHPGGGDQIFIQGHASPGIYARAYLEGRLSEEQLFRFRQEVQHGQGAGLSSYPHPRLMPDFWEFPTVSMGLTGINSIYQARFNRYLHNRGVKDTSQQHVWAFLGDGEMAEPESLGAIRIAAREELDNLTWVINCNLQQLDGPVTGNGKIIQELEANFRGAGWNVIKVVWGREWDALLARDVDGVLVNKMNSTPDGAFQTFSVESGAYNREHFFGPDPRLRAMVEHMSDRQIEKLPRGGHDYRKVYAAFDSATKHVGQPTVILAHTVKGWTIDALEGKNATHQMKKLTKDDLKKFRDRLYLPISDRDLETAYEATGAAPFFHPGAQSPEIEYMMERRRQLGGSLPQRVDRSTMLTLPGDATYAELKKGAGTHKVATTMAAVRLLKDWMKDPGIGQRIVPIAPDEYRTFGMDAMFPSAKVYDPHGQQFESVDRNMLLSYKMSTQGQMLHEGISEAGAMASAIAAGSSYTTHGEPMIPFYIFYSMFGFQRTGDSIWAMADQLSRGFLVGATAGRTTLTGEGLQHADGHSPLIAATNPAVVHYDPAFGYEVGHIMRSGLERMYGSSEEHPRGEDVIFYLTVYNEPVAQPAEPEGLDVAALLKGMYRVAEAPAAEGPRVRLLASGVGFPWIDEAKRLLADEWGVQAETWSVTSWNELARDGIATEKWNLLHPDEAHRTPYVTSALGEGPAAQAPVVAVSDYMTAVPLQIAQWVPADYRVLGADGFGFADTRPAARRFFQVDAQSVVVQALAALADAGEIDPARVKEAVDRYRIDDPTAAAGVLQEGGDA
>NZ_CP009896.1|WP_038679968.1|3495759_3496146_-|hypothetical-protein
MVVALAVAACDAPSGPAEITLLTAPATTSVGGFKARLAGTAGLTDGGCVVVDGHLLVAPEGARVRGDVIEIPGYPGFRVGDHVVLGGGEAEAGASGLPGTTQCGVPSDEDAPHWVVAAGGPAQASPPS
>NZ_CP009896.1|WP_052138802.1|3496286_3496991_-|FadR-family-transcriptional-regulator
MTIENDAGSSLSELFAADPLSVALAELIQEMRPGDKLPSERDLAVRLDVSRTALRDRLGMLEGLGVLRRRTGAGTFVETLRPDALAFALNLAISSSHLPLASLESVRIALERQAAAEAARRADPVLIAYMKRAIDTMAATELSADVLDADRAFHQSLLRAAGNPSLTFFAEALSNVLTKDLADRSERLLHEPLTTSRQALLVDHHTRIYDAILAGDPDAAMRAVDGHFDAIGNS
>NZ_CP009896.1|WP_038679970.1|3497146_3497389_+|hypothetical-protein
MSTSVSITELGDGVEEAVLATWLCAVGDSVAAGEPIAEVMTDKVNLEIGAPVAGVVTALHGEPEDTVRIGQVIAEIGDPA
>NZ_CP009896.1|WP_052138803.1|3497385_3498357_+|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha
MTTTTTTITETGLWQAMVEARAFDQAMCRHNGHWHEARGEEAVFVGAFAELGPDDVVAPHFRGACAVALQRGSSPATLAAGVFGTDASSSGGHWRGDICPAPGPRSVGMFSGSLGTSVAYATGAALHLSRTSPGAVAVCGFGDGTANSGIVAESLNLAAMLGLPVVYVCQDNQYATSLPSAVALAGERVSDRARALGIPATDVDGNDVLAVRDAIGEAVARARAGAGPSFVHALTYRMGGHYMNDPETYRSPEEVAAWAERDPIARLQDQLVARGELTADDATAQVRAADERMEAIVAAAKGASDAALVRATSPYAEDLRSAS
>NZ_CP009896.1|WP_038679972.1|3498353_3499346_+|alpha-ketoacid-dehydrogenase-subunit-beta
MSRMTMSEAIVAAIADAMTADPSVYLMGQDIGVFGGPMQSTKGLWDSFGAQGRVIDAPISEAAMVGTAVGAAMAGSRPIVDLMFAEFLALTMTPLGLEGSAVAFRTRGEVTVPLVVRAKCGVGPHRGHAESCVGMLLAFPGLKVAMPTTPQDAYSLTRAAIRDDNPVVLLEHMSLLHGARAEVDRTLDVRLGAADIRRPGRDLTIAASGLMVQRAVRAAKDLAADGVEAEVVDLRSLAPLDTALVRASAERTGALLVAEESWPGSGPAAALCAALLGDGDRLGFPVRLLQPPPTPVPFAASLESAFVPSVADIADAARALHAPVKGTVTA
>NZ_CP009896.1|WP_052138804.1|3499342_3500728_+|aspartate-aminotransferase-family-protein
MTTTPATPASQVFHRDLVHSAPAVSHASGVHVWDADGNEYLDASSGGNIVISIGYGVQEVLDAMAEQAAKVSFCGQFTSEPQEQLARELADFAPEGMDYVRFTSGGSEANETAIKLARHYFVESGKPSKHKIVGRWRSYHGNTLGALSATGHVMRRTGYAPMLLPFAHAQPPYRYRCTLCAQSNACTLSCADDVERVILNEGPEHVAAFIAEPIVGAAAMGMVPPDGYFERVREICDKYDVLLIVDEVLTGMGRTGRNFAIEHFGVVPDLITCGKGISSGYSPLGAVIARNEIYDAVANGSGMFEHGFTYGGNPLSCAVGLAVLRHIEKHDLVARAGEVGGYLLSEVQRAIGDHPLVGEVSGLGLLVGVEIVADRATKEPFPYEAGVSKRIARACQERGVLINPSFSGNADGYRGDRFGICPPYVFERHHVDQTVAALAAAVDQVAAELASRVPTTTKESQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_10

3535146-3535236

Orphan

Consensus_repeat	Method
GGCAGTTTCACCGCCTAAGCGGTGAAACTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_10

>merge|NZ_CP009896|10|3535146-3535236|CRISPRCasFinder
GGCAGTTTCACCGCCTAAGCGGTGAAACTGGGCGTTGGCCCACGAAACTCCCTCGGCAAACGGCAGTTTCACCGCCTAGGCGGTGAAACTG

>NZ_CP009896|10|10|3535146-3535236|CRISPRCasFinder
GGCAGTTTCACCGCCTAAGCGGTGAAACTG	GGCGTTGGCCCACGAAACTCCCTCGGCAAAC
GGCAGTTTCACCGCCTAGGCGGTGAAACTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038680026.1\|3537830_3538793_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038680012.1\|3530636_3530984_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223372
NZ_CP009896.1\|WP_038680028.1\|3538824_3539742_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371178
NZ_CP009896.1\|WP_082003701.1\|3533981_3535052_-\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224616
NZ_CP009896.1\|WP_038684767.1\|3532228_3533518_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP009896.1\|WP_038680022.1\|3535668_3536535_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237361
NZ_CP009896.1\|WP_082003702.1\|3537270_3537834_+\|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|132028
NZ_CP009896.1\|WP_038680020.1\|3535255_3535603_-\|HIT-domain-containing-protein	unknown	unknown	gnl\|CDD\|238607
NZ_CP009896.1\|WP_038680008.1\|3528865_3529657_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|366444
NZ_CP009896.1\|WP_038680030.1\|3539748_3540801_+\|winged-helix-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|377630
NZ_CP009896.1\|WP_052138810.1\|3536622_3537195_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP009896.1\|WP_038680016.1\|3531318_3532242_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|225130
NZ_CP009896.1\|WP_038680014.1\|3531025_3531313_+\|DUF1330-domain-containing-protein	unknown	unknown	gnl\|CDD\|377765
NZ_CP009896.1\|WP_038680005.1\|3527124_3527742_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP009896.1\|WP_038680034.1\|3541562_3542732_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237654
NZ_CP009896.1\|WP_038680018.1\|3533514_3533985_-\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|234575
NZ_CP009896.1\|WP_038680010.1\|3529653_3530568_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP009896.1\|WP_038680036.1\|3542745_3543780_-\|heat-inducible-transcriptional-repressor-HrcA	unknown	unknown	gnl\|CDD\|234621
NZ_CP009896.1\|WP_038680006.1\|3527738_3528848_-\|histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP009896.1\|WP_038680033.1\|3540805_3541549_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|236959

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038680012.1\|3530636_3530984_-\|hypothetical-protein	gnl\|CDD\|223372	COG0295, Cdd, Cytidine deaminase [Nucleotide transport and metabolism].	0.00245623
NZ_CP009896.1\|WP_038680028.1\|3538824_3539742_+\|hypothetical-protein	gnl\|CDD\|371178	pfam10648, Gmad2, Immunoglobulin-like domain of bacterial spore germination. This domain is found linked to the GerMN domain pfam10646 in some bacterial proteins. It is predicted to contain an immunoglobulin-like all-beta fold.	1.3787e-23
NZ_CP009896.1\|WP_082003701.1\|3533981_3535052_-\|PhoH-family-protein	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	2.68376e-143
NZ_CP009896.1\|WP_038684767.1\|3532228_3533518_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.79009e-104
NZ_CP009896.1\|WP_038680022.1\|3535668_3536535_-\|hypothetical-protein	gnl\|CDD\|237361	PRK13355, PRK13355, bifunctional HTH-domain containing protein/aminotransferase; Provisional.	0.000347657
NZ_CP009896.1\|WP_082003702.1\|3537270_3537834_+\|SigE-family-RNA-polymerase-sigma-factor	gnl\|CDD\|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	5.08236e-37
NZ_CP009896.1\|WP_038680020.1\|3535255_3535603_-\|HIT-domain-containing-protein	gnl\|CDD\|238607	cd01276, PKCI_related, Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a hydrophobic residue) that is a signature for this family. No enzymatic activity has been reported however, for PKCI and its related members.	1.06844e-41
NZ_CP009896.1\|WP_038680008.1\|3528865_3529657_-\|ABC-transporter-permease	gnl\|CDD\|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	9.23221e-09
NZ_CP009896.1\|WP_038680030.1\|3539748_3540801_+\|winged-helix-DNA-binding-domain-containing-protein	gnl\|CDD\|377630	pfam06224, HTH_42, Winged helix DNA-binding domain. This family contains two copies of a winged helix domain.	5.55112e-38
NZ_CP009896.1\|WP_052138810.1\|3536622_3537195_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	7.78801e-20
NZ_CP009896.1\|WP_038680016.1\|3531318_3532242_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|225130	COG2220, COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only].	7.48428e-16
NZ_CP009896.1\|WP_038680014.1\|3531025_3531313_+\|DUF1330-domain-containing-protein	gnl\|CDD\|377765	pfam07045, DUF1330, Domain of unknown function (DUF1330). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	2.48119e-23
NZ_CP009896.1\|WP_038680005.1\|3527124_3527742_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.82257e-62
NZ_CP009896.1\|WP_038680034.1\|3541562_3542732_-\|molecular-chaperone-DnaJ	gnl\|CDD\|237654	PRK14278, PRK14278, chaperone protein DnaJ; Provisional.	0
NZ_CP009896.1\|WP_038680018.1\|3533514_3533985_-\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	3.7801e-64
NZ_CP009896.1\|WP_038680010.1\|3529653_3530568_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.37892e-77
NZ_CP009896.1\|WP_038680036.1\|3542745_3543780_-\|heat-inducible-transcriptional-repressor-HrcA	gnl\|CDD\|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	2.70273e-144
NZ_CP009896.1\|WP_038680006.1\|3527738_3528848_-\|histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	5.99394e-37
NZ_CP009896.1\|WP_038680033.1\|3540805_3541549_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|236959	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional.	1.18192e-71

>NZ_CP009896.1|WP_082003701.1|3533981_3535052_-|PhoH-family-protein
MTDSTSPVTAAAAAPAAPVRHVIVVPNSIDMVTLFGPGDEHLGIIERQLRVEVHVRGNRVTLAGEADEVKLAERLIEELVAILRTGQGITSEVVERVEAMLRAETATSERPADVLSLNILSNRGRSIRPKTLNQKRYVETIDQHTITFGIGPAGTGKTYLAMAKAVQALQAKQVNRIILTRPAVEAGERLGYLPGTLSEKIDPYLRPLYDALHDMLDPESVPKLLAAGTIEVAPLAYMRGRSLNDSFIILDEAQNTTPEQMKMFLTRLGFGSKIVVTGDVTQVDLPSGTSSGLRVVENILEGVDDLAFVRLTSHDVVRHKLVARIVAAYDDFDAQKEAKRELRQDRRLDSKKGDPA
>NZ_CP009896.1|WP_038680018.1|3533514_3533985_-|rRNA-maturation-RNase-YbeY
MSIEILDESGSGLDVKHFARLARFVMDQMRVHPLAELCIKSVDEDTIAELNEKWMDKEGPTDVLAFPMDELRPGLVNEEPEEGVLGDIVLCVAVAERQGATAGHGTLAELELLTTHGILHLLGYDHAEPEEHKVMFGLQDQLLAQWRAEPPAQPDA
>NZ_CP009896.1|WP_038684767.1|3532228_3533518_-|HlyC/CorC-family-transporter
MIADSLWPLGAAAVLVVLAGLFAAADAALAGFSRARAHEMLSEGRGGARRLIAVLDDAPRHLNTALLLQLLCESAAIVVVTLYVDERLDASWWARAGLALGVMLVVSFVVIGVAPRTVGRQHAETVALWSAWPLSMLTTVLGPIPRLLILVGNAITPGRGFREGPFQTETELRELVDMAEATELIEADERKMIHSVFELGDTTVREVMVPRGDVVYIEAHKNLRQTMSLFLRSGYSRLPVVGENLDEVRGIAYLKDVARRDFEAPDVELTQRVEEVMRPVHWVPESKPVDDLLREMQARRRHVAIVVDEYGGTAGLITIEDLLEEIVGEITDEHDEAEVEVERVGERVRVPSRYPVDDLDEIFGFPIEEEDVDSVGGLLAKHLGRVPIPGSVVEAYGLRFEAEHTAGRRNKIGTVLISRVPDEAGVSAD
>NZ_CP009896.1|WP_038680016.1|3531318_3532242_+|MBL-fold-metallo-hydrolase
MRPRLGRPDIRRYADRFGLPQSDDGLGVTFLGVATLLLDDGATSVLTDGFFSRPSLPRVLLGRIGPDAARIDAALARARIDRLDAVAPVHTHYDHAMDSAVVAARTGATLYGGTSTAHVGSGGGLPADRVEVVVPGAPVSIGGFRLTWLESEHCPPDRFPGTITEPVVPPVKVGAYRCGEAWSILVEHDSGRTALVQGSAGFVPGSLAGRSAEVAYLGVGQLGVQSPDYIRRYWAETVETVGAREVVLIHWDDFFRPLDRPLRCVPYLGDDLDATMDVIAGLARDQGVGLHFPSVGRREDPWRLSRR
>NZ_CP009896.1|WP_038680014.1|3531025_3531313_+|DUF1330-domain-containing-protein
MPAYWISNYRAVHDADKMAAYAALALPALVDAGGTFLARGLPEQVYEAGLQERVVIIEFPSVEAAIAAHDTPAYQEALAALGDGAERDLRIVPGA
>NZ_CP009896.1|WP_038680012.1|3530636_3530984_-|hypothetical-protein
MPDLSTEDQKLVILARATRARIRAAEGAAVRDTDGRTYAAATVDLPSLRLTAVQAVVAMAVASGASGVDACVVLGESAELADDDAAVLTDFAGAGGVAVHVGDPRGTIGASLTRP
>NZ_CP009896.1|WP_038680010.1|3529653_3530568_-|ABC-transporter-ATP-binding-protein
MTTNTTNATAPAVRLAGVTKEFGDVRAVWGIDLALRPGEIVAFLGPNGAGKTTNIDMLLGLTKPTSGTVEVLGMEPRKAIARGLVSAVMQTGGLLKDLTVRETAAYMASLFADTRPVDEVLDRAGIAGLADRKVGKCSGGEQQRLRFAMALLSDPALLLLDEPTTGMDVEGRRAFWSAIRDDASSGRTVLFATHYLEEADQYADRIVLISQGQVVADGTGPQIRALASGRTIRAWLPDADVAAITALGGVDHVEVRGESVTIHAKDSDTVARYLLTATPARDLEITAKGIEEAFLSLTGQGESA
>NZ_CP009896.1|WP_038680008.1|3528865_3529657_-|ABC-transporter-permease
MSTTTGTLDPATRRVPPLGGLNRTVLGIELRRMLRNRRTVIFTLVLPAALMLSFGGQSGWDDKVGVGNVGAYILASMAMYGAALTAAAGGSMVALERSLGWSRQLRLTPLHPVAYILMKAFVALVMGALAIVAVNLVGILQGKAEMPTSTWIQCGALALVCTLTFAALGVFIGYVVPGENAMQILGPGLALLSFLGGLFIPLSQYAEGVRLVAYWTPMYGVAEVVRAPLTHELPWYAVVNAVGWCTLFVAGAAWRMSKDTARV
>NZ_CP009896.1|WP_038680006.1|3527738_3528848_-|histidine-kinase
MSETAPAAPRVVGRRGPWFAAIWLFFLIDPVRAGFQADDRVRGLSGVATTVVFAGVYLLLWWRMRARAQAFGDPVGETPGAGSALLLTLAGLGVLMMVLLGEPGVACLVYVAVAAVMVMPVRWAAPTVIAIAVLAVLLGLLPGWEFEFGVAFGVVAASVAVFGIRTIINRNAQLVTAHQRNAELAVDNERSRFARDLHDILGHSLTVITIKAELARRLIDVDPERTRAELADLERLSRDALADVRRAVEGYRDLTLPGELARARTALSAAEIEATLPNSTEDVPSELRELFAWTVREGVTNVIRHSGARHCEVVLGPGRAEVRDDGAGPGTPSVRGSGLAGLQERAAALGARLVTTKLDPGWSLAVVVE
>NZ_CP009896.1|WP_038680005.1|3527124_3527742_-|response-regulator-transcription-factor
MSAETIRLLLADDQALVRGALSALLGLERDLEVVAEVGTGEEAVAVAAELRPDVALLDVEMPGIDGITACARLRAVAPATRVLIVTTFGRPGYLRRALQAGASGFVVKDTPAPQLADAVRRVHQGLRVVDPALATDSLVSGESPLTGRESDVLRAARDGASVAAIAGALFLSEGTVRNHLSSAIGKTGASNRTEAVLVADGNGWL
>NZ_CP009896.1|WP_038680020.1|3535255_3535603_-|HIT-domain-containing-protein
MTADPDCLFCKIVAGDIPGDIVHTGERTLAFRDINPQAPLHVLVVPRDHEPNAAASAHADPEMFAEIATTARAVATAEGYDDYRLVFNTGAGVGQTVFHTHCHVLAGRPMTWPPG
>NZ_CP009896.1|WP_038680022.1|3535668_3536535_-|hypothetical-protein
MGVGTGDLQTTFADALGAAMERRGATLTHLRDRLADRGHPVSLTALSYWRSGQREPERSASLEAIPELEALLGLEQGALSRRLSGRMRRRVGAVEPFDELLGDPAVDAVIGEEDVCRVSSHLVVDVGAQGEIQRARVRQVLVADREGVDGVTLFVGPDVGTQENDIVMEAVAGCSIEEISDLENGIRGSRLVFERPLALGESTITEIEARRAHGLDLETDYALAAEQRLEEALVWVRFHPDKVPSRCWVYFQEGGLRHAWPVDLDGGRSVHYRQTAFGPGYLGVRWEW
>NZ_CP009896.1|WP_052138810.1|3536622_3537195_+|sigma-70-family-RNA-polymerase-sigma-factor
MGIDELTDEKLADRVRRGVDAEEAFEELFRRHRAVLLRVARSIVPGEEEDAVAEAYLGLLGVLRSGGGPSYGVRSYLIASARNRALRRAYVRARSVVADVPRLLEGRDGVEPDLTWVHEGDLLSRAFRALTPRQQQVLWALEVEGRRPRELAPVLGCDAAAVSAVAHRARRRLRDLYLAQLAEPEVARAG
>NZ_CP009896.1|WP_082003702.1|3537270_3537834_+|SigE-family-RNA-polymerase-sigma-factor
MLGAPSLPAGAERPVVTDADLAIEQLYLEHWHHLVRLSVLLVRDPGQAEEIAQDAFVELHRRWGRLDDPERAPAYLRQTVVNRSRSALRHRGVVQRHLARQHVVDLAPAADEPVLADSRRRLVLDALQRLPRRQREVLVLRYYLDLSEAEIAETLGISRGAVKSHASRGSATLRPLLEARDLKGGDR
>NZ_CP009896.1|WP_038680026.1|3537830_3538793_+|hypothetical-protein
MSADEDAQLRALFSDAVADVDPADRLGEIRRRTSQRPRRSRRRPLLVVLGAGTATAAVVAITALATDFRDDRDAPVASGPAEYPGAVYFVSSTTLGPRLFREFQPLPASDDVAVRALDALQQMEVDAGPVDGDYATGWPDGSFTAVSVDDTAITVQVGAVALDAPAGVSPDLATLAVQQAVHTADAAVGRPLPVAFERAGTPVARLLGRPVELPAVRNTRVEAPVNLNDPVEGLEVGAALAVRGQVTPVAAEAVSRVSWQLEDASGATQLAGTTAVDAQAWQMTLDVSALPRGRYRIVVWPDHDDPDVSGAVDTRSFVLR
>NZ_CP009896.1|WP_038680028.1|3538824_3539742_+|hypothetical-protein
MTSALPRTLATLGGAVLALGLLAGCGDDEPAADKPATPSSSAPASSPAATEGTETGSPSTDPGAPDPSAIPVYYVGKTPQGDRLYREFTQISGADRLVAAAASVTSGKPVDPDYRTSWPGGRFASVTQTADAIVVEVPDASWLQPGSLKPAQARLAVQQLVYTLQGTAGARLPVQVQQDGKPAPTLLGVDASKGLTAAPELDVLALVNVTEPAEGTAVDGKFTAEGRASSFEATVPWEIQDATGKVVQQGFTTAEGWADKLYPWSTKVDVSALPPGQYTFIARTDDPSDGEGGGPTEDTKRITVK
>NZ_CP009896.1|WP_038680030.1|3539748_3540801_+|winged-helix-DNA-binding-domain-containing-protein
MRFSRARLNRTLLLRQHLLERVALSPAEMVGHLVGLQAQESLPPYLSLAARLDDLDPHAVSAAIEDRSLVRVLSLRDTVHLHLPDDAVTLPVWAAPVREREIRASQTIGSAREVDRAAFSAAVHEVLADGPLPQRRLGAALAERFPDYTATQLGQVARVAEVLAQLPPRGCWKPSGSTAVAYDLADRWTGLPLAEPDVPALVRRFLRAYGPGTAADVTAWSGITRLGPVVKAMDDLVVHEDDDGKALYDVPDAPVADEDAPAPVRLFGTYDNLWLSHASRDRVMAPEHRRLWMGVNGAQAMSIHVDGWFTGLWRAEEGRVVVVEMVRELSRTERADLDDEIARVEALLAR
>NZ_CP009896.1|WP_038680033.1|3540805_3541549_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MTLPQHLVPSLESVRAGDEVLVDGDEAHHAVVVRRLRVGEGLQLADGWGRVATAEVSATTKRSFTARVTDVTDHAEPRPRVTVVQALPKGERGELAVEVLTEIGVARIVPWAAARSVAVWKGERAAKSLAKWQATAREAAKQSRRAWHPQVVPLATTDEVAALVGEADVAIVLHEDAAEPLGALALPDDGELLVVVGPEGGLTDDEVARLVDVGAVSVRLGTEVLRTSTAGVAAVAALLVRTPRWGD
>NZ_CP009896.1|WP_038680034.1|3541562_3542732_-|molecular-chaperone-DnaJ
MSHDPYELLGVDREADADTIKKAYRKLARQLHPDVNPDPESQERFKQVTAAYEVLSDPQKRAAFDRGGDMFGGAGFGGQGAGFSFTDIMDAFFGGAGGGQQAGRGPRPRVRRGQDALIRLEVELAEAAFGVSRELKVDTAVRCSTCSGEGTAPGTHPVPCETCHGMGEVAHVQRSFLGEIRTLRPCAACRGFGTIIPDPCRECAGDGRVRSRRTLTVKIPAGVDNGTRVQLSEQGEVGPGGGPAGDLYVEIHVAPHEMFERHGNDLHCTVSVPMTAAALGTTLHLPTLEADLESGADSGVETSFELGVPPGTQSGHQVVLRGRGVPGLRGGRGDLAVTVAVETPSRLDPRQEELLRELAAIRGEEQPTGDVRPPHKSVFGRLRDAFTAH
>NZ_CP009896.1|WP_038680036.1|3542745_3543780_-|heat-inducible-transcriptional-repressor-HrcA
MQEERRLAVLRAIVEDYVATEEPVGSKTLVERHHLNVSPATIRNDMAALEEEGYLHQPHTSAGRVPTDKGYRLFVDRLSTVKPTTSAERRAIASFLDGAVDLDDVVHRSVRLLAQLTRQVAVVQYPSLSRSTVRHVEIVALTPTRLLLVLILSSGRVEQRVVELEAALADDELAALRSRINLAATGEVIADAATALDALVRPADDDERAPAPSAAALAVVEALVEAMSDHRSDERVIVGGTANLARFGDSFETSVRPLLEAIEEHVVLLKLLGEATSGGAVTVRIGAEGPFEELASTSVVATGYGPDDALAALGIVGPTRMDYPGTMAAVRAVARYVSRILDES

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_11

3911990-3912078

Orphan

Consensus_repeat	Method
AGTTTCGCCGGTCGACCGGTGAAACTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_11

>merge|NZ_CP009896|11|3911990-3912078|CRISPRCasFinder
AGTTTCGCCGGTCGACCGGTGAAACTCACACTGGACCGACGGAACTTCATCGGTCAGGTGTGAGTTTCGCCGGTCGACCGGCGAAACTC

>NZ_CP009896|11|11|3911990-3912078|CRISPRCasFinder
AGTTTCGCCGGTCGACCGGTGAAACTC	ACACTGGACCGACGGAACTTCATCGGTCAGGTGTG
AGTTTCGCCGGTCGACCGGCGAAACTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038680554.1\|3917051_3918965_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_052138872.1\|3900930_3901806_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP009896.1\|WP_052138874.1\|3902503_3903511_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270275
NZ_CP009896.1\|WP_052138875.1\|3904322_3905081_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NZ_CP009896.1\|WP_038680542.1\|3903507_3904326_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NZ_CP009896.1\|WP_038680548.1\|3912081_3912528_-\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176860
NZ_CP009896.1\|WP_038680549.1\|3912537_3913620_-\|glycosyl-hydrolase	unknown	unknown	gnl\|CDD\|374209
NZ_CP009896.1\|WP_052138876.1\|3906108_3906996_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|238527
NZ_CP009896.1\|WP_038680561.1\|3921447_3922383_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP009896.1\|WP_038680551.1\|3913746_3914052_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_075018488.1\|3910110_3911958_-\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|237104
NZ_CP009896.1\|WP_082003728.1\|3901891_3902371_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP009896.1\|WP_038680544.1\|3905077_3906112_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|223787
NZ_CP009896.1\|WP_082003729.1\|3906992_3908198_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274652
NZ_CP009896.1\|WP_082003730.1\|3914041_3916894_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226415
NZ_CP009896.1\|WP_038684953.1\|3919032_3919884_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|227339
NZ_CP009896.1\|WP_141267583.1\|3919897_3920551_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038680562.1\|3922379_3923558_+\|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|369642
NZ_CP009896.1\|WP_141267581.1\|3920624_3921338_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038680546.1\|3908194_3909133_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270272

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_052138872.1\|3900930_3901806_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.06516e-31
NZ_CP009896.1\|WP_052138874.1\|3902503_3903511_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270275	cd13557, PBP2_SsuA, Substrate binding domain of sulfonate binding protein, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes the sulfonate binding domains SsuA found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBPII superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.14312e-37
NZ_CP009896.1\|WP_052138875.1\|3904322_3905081_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	4.72973e-87
NZ_CP009896.1\|WP_038680542.1\|3903507_3904326_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	6.26135e-62
NZ_CP009896.1\|WP_038680548.1\|3912081_3912528_-\|SRPBCC-family-protein	gnl\|CDD\|176860	cd07818, SRPBCC_1, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	1.22063e-55
NZ_CP009896.1\|WP_038680549.1\|3912537_3913620_-\|glycosyl-hydrolase	gnl\|CDD\|374209	pfam15902, Sortilin-Vps10, Sortilin, neurotensin receptor 3,. Sortilin, also known in mammals as neurotensin receptor-3, is the archetypical member of a Vps10-domain (Vps10-D) that binds neurotrophic factors and neuropeptides. This domain constitutes the entire luminal part of Sortilin and is activated in the trans-Golgi network by enzymatic propeptide cleavage. The structure of the domain has been determined as a ten-bladed propeller, with up to 9 BNR or beta-hairpin turns in it. The mature receptor binds various ligands, including its own propeptide (Sort-pro), neurotensin, the pro-forms of nerve growth factor-beta (NGF)6 and brain-derived neurotrophic factor (BDNF)7, lipoprotein lipase (LpL), apo lipoprotein AV14 and the receptor-associated protein (RAP)1.	5.10473e-09
NZ_CP009896.1\|WP_052138876.1\|3906108_3906996_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|238527	cd01094, Alkanesulfonate_monoxygenase, Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin mononucleotide (FMNH2), which is provided by the NADPH-dependent FMN oxidoreductase (SsuE).	6.94419e-19
NZ_CP009896.1\|WP_075018488.1\|3910110_3911958_-\|dihydroxy-acid-dehydratase	gnl\|CDD\|237104	PRK12448, PRK12448, dihydroxy-acid dehydratase; Provisional.	0
NZ_CP009896.1\|WP_082003728.1\|3901891_3902371_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.56473e-16
NZ_CP009896.1\|WP_038680544.1\|3905077_3906112_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|223787	COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism].	1.19984e-24
NZ_CP009896.1\|WP_082003729.1\|3906992_3908198_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274652	TIGR03565, alk_sulf_monoox, alkanesulfonate monooxygenase, FMNH(2)-dependent. Members of this protein family are monooxygenases that catalyze desulfonation of aliphatic sulfonates such as methane sulfonate. This enzyme uses reduced FMN, although various others members of the same luciferase-like monooxygenase family (pfam00296) are F420-dependent enzymes. [Central intermediary metabolism, Sulfur metabolism].	4.8864e-84
NZ_CP009896.1\|WP_082003730.1\|3914041_3916894_-\|AAA-family-ATPase	gnl\|CDD\|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	1.82587e-21
NZ_CP009896.1\|WP_038684953.1\|3919032_3919884_+\|EamA-family-transporter	gnl\|CDD\|227339	COG5006, rhtA, Threonine/homoserine efflux transporter [Amino acid transport and metabolism].	2.25714e-68
NZ_CP009896.1\|WP_038680561.1\|3921447_3922383_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.67462e-23
NZ_CP009896.1\|WP_038680562.1\|3922379_3923558_+\|PQQ-dependent-sugar-dehydrogenase	gnl\|CDD\|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	2.04221e-90
NZ_CP009896.1\|WP_038680546.1\|3908194_3909133_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270272	cd13554, PBP2_DszB, Substrate binding domain of 2'-hydroxybiphenyl-2-sulfinate desulfinase, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes DszB, which converts 2'-hydroxybiphenyl-2-sulfinate to 2-hydroxybiphenyl and sulfinate at the rate-limiting step of the microbial dibenzothiophene desulfurization pathway. The overall fold of DszB is highly similar to those of periplasmic substrate-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The DszB protein belongs to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.1912e-57

>NZ_CP009896.1|WP_075018488.1|3910110_3911958_-|dihydroxy-acid-dehydratase
MPTLRSATSTSGRNMAGARALWRATGMTDSDFGKPIIAIANSFTEFVPGHVHLRDVGKIVAESVVANGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADAVEYMVQAHCADAIVCISNCDKITPGMLLAALRLNIPVVFVSGGPMEAGKTTAIEGIVHSKLDLVDAMSASANDAVSDEQLDVIERSACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSTLATHAKRRALFEEAGKVVMDLCRAYYENDDESALPRNIATREAFENAVALDVAMGGSTNTVLHLLAAAREAELDFSVHDIDAISRRVPCLSKVAPNSPKFHMEDVHRAGGIPALLGELRRGGALHENVHSVHSPDLDSWLGAWDIRAESPSAEALELFQAAPGGVRTTEPFSTENRWGELDTDAAEGCIRDFEHAYSADGGLAILSGNVAVDGCVVKTAGVAEEALVFHGTAIVFESQDAAVEGILGKKVEAGHVVVIRYEGPKGGPGMQEMLYPTAFLKGRGLGAKCALITDGRFSGGTSGLSIGHISPEAAGGGLIALIEDGDPISIDIPNRSIHLDVDDHVLAERRVLQEKRDKPYTPLDRQRPVSAALRAYASMATAASDGAYRRVPD
>NZ_CP009896.1|WP_038680546.1|3908194_3909133_+|ABC-transporter-substrate-binding-protein
MTTRIGYFPSNNSLFVLRHRGIVEQRLPDVEWVDFRDLPQSRVGVREGLPTAHADHLFTDGGYDVIGTGFTPPITGLGQGHDLVYVGVSEPRIANGRLVARADSGIATVADLKGKRVGIGHGSWQTTLLLFALDQVGLGWADVEPVDTAGLDAGQALLDGELDAWTGSYPELTAVEAAAPLTTLVETDGLFSHPSLWFTRRDFATAHPDELRAIVESLQESDAWIAAHPREAAQYFVDDAARRGRRADLDEWTHALATRPFGIHPPSEEFLDEQQRAADLLHRNGLLPKPVTVRDAYLPELADVVTQTRQVA
>NZ_CP009896.1|WP_082003729.1|3906992_3908198_+|LLM-class-flavin-dependent-oxidoreductase
MMVDIYWRIGTHGDQPSLRQRVASRGDWSPTGPGSIAPGLRDGGRDGYTYLDHMADVARAAEVSGFVGGLLPSFPFTDDPWVAASALVRETRSFRFMVAFQPGFLDPFHAARISATLQRVSGGRLVYNIITGGGGPEQTWWGDPVAHDDRYARTGEFLEALQGTWGTAPYDLAGRFYDVRGASLPPDLAAQAVPEIYFSGSSPAAIATAGGYADYYLSWLEPFDALREKFAEVRERSATLGRRPRFALRVEVLARETEAEAWAELERGWAQVDLAAVNAATGGDSVGAARSRAFVRGPVRTPRDMEVEPQVWGGFHLLRGGPAFGLVGSYAQVAARLEELVEIGVDSFILAAVPHLEEAYRIGSEVLPRLSVHKTGYVGHPGHPTSPAAPAAPAPIERNAS
>NZ_CP009896.1|WP_052138876.1|3906108_3906996_+|LLM-class-flavin-dependent-oxidoreductase
MSHPAPRFLVPLATRDERSWPGFDIAEQRAQALRAAELGGFAGVVAADDLGGDEASVVAYDALRASRWLEVVQELPISRGNPVYAAKQAASAQRFFDGRLGWQLVVDEPGPSQTTPPARTRAERYARATEFLTVARGVWHDTEFTFEGRYHQVVGGGFREALADLPFPRLHLTGSSDEALALSARFADVHLFDDLDTALAHGPALRAAAGDRPLEIGVALRVVAREHRPEVPRTIDPRTALVGTYDELAERLAELVAAGITTYLLDAHPRIEETYRIAEHLLPRVRDLTPAGGAR
>NZ_CP009896.1|WP_038680544.1|3905077_3906112_+|ABC-transporter-substrate-binding-protein
MTTTPTSLDTLWYTRCPVPTASGIAHRLGWLADDFARDDLALQVLQDAPPEIAEHHFDHLLVGLFREGGNVPALVARAEGAPTRLIGLTWIDEGQRVVVRPDSGIASAADLAGRRLAVPGWAGTRTRSFPRAMALHGLTSALRTAGLTLADAELVEVPGRADRRPGWDPSAAAHWPGLDELAAGTVDAVYLKGGRSAEQAAAAGLVVAVDLDATPSLADRVNNGTPRPITVHAALLDERPELVVRFLAQTLRAARWATEHPDEVRAFLGSEVGSGGDGVTTAYGADVHLGLTPDLSPERLALLDQQQRFLHEHAFTDAPVDVQAWADPAPLAAARRLLDEEEGR
>NZ_CP009896.1|WP_052138875.1|3904322_3905081_+|ABC-transporter-ATP-binding-protein
MTVTLATATGGSTTSPAPAVRIRGLRKVYDGKAVLDGIDLDVAPGQLVALLGPSGTGKTTLLRLLAGFERPDAGELGVPLARTTVYQEPRLVPAHRVLRNVMLGQRGTAANRAAALASLAEVGLADKARSWPATLSGGEAQRVALARALVREPRLLLLDEPFAALDALTRLKMHDLVERLRRRHDPAIVMVTHDVDEALRLADRVVMLRDGHVSVDLLVDLPHPRAITDPHLLAHRRRLLAELGVDTPEATP
>NZ_CP009896.1|WP_038680542.1|3903507_3904326_+|ABC-transporter-permease
MTTADVLVTPRFLGTRRRSRSWSLLTRASVPVALLVVWQAASATGLLDPQVLASPGSVVGALRELAESGQLADFLAASATRAAIGVSLGVVAGLVLGVLAGASALGEELIDPSMQMYRAVPFLALVPLLLSWFGVGETFKIVLIAVSAVAPMYAYTYLGVRGVDRKVVEAARGFGLRGFRLVWEVILPCARPNLLMALRICLSVSLTGLIAAEQIGTTEGIGYLVSLSQQYFRSDYMVLCILLYALLGVLIDTAIRFLEHVALPWRSGVAAR
>NZ_CP009896.1|WP_052138874.1|3902503_3903511_+|ABC-transporter-substrate-binding-protein
MSQHPRRTTAFAAAALLVLAALGLTACDAANGDDGGTTVLRIGDPGNEGVLAYAKKTGVLEDRLEKVGAKVEWGGSYASFTATIDAVRSGDVNVLQGAISPAIGYLSTSDDLKIFTVAPRTTDPDAPVADGLVVPADSSVTSIDQLVGKKIAVNRGGRGEYLLDLALDKAGIEHDAVEKVYLNPAEAAGAFASGKVDAWWAIVRGYPLAVANGAKTIVTNTDVEDNDLTIFAARSEVVEKNPEALEVFQEVVADLVKEANAEPEKFQNVFTDSGPTATSGDLLEHDTESLRYELPPALATDADVAKVQQVADYFLENGLISKPVDADAAVARLGR
>NZ_CP009896.1|WP_082003728.1|3901891_3902371_+|MarR-family-transcriptional-regulator
MGMPRAERRPTMTAEARFTSPGYLLAHIGRMAHRRIADSLEPLDLQPREAAVLLVLRDHDGELSQQRLGQVLDMDPNYLVKALARLEDAGLVARRPDPDDRRRQVVTLSAAGRRRRAAADESVTRAESEILAGLSPEDAARLRELLLVLDRNSGSAAHD
>NZ_CP009896.1|WP_052138872.1|3900930_3901806_+|LysR-family-transcriptional-regulator
MNIQQLRYVVATAEHGSMTAAAAALFVAQPALSRAVRQLERELDLTLFARDGRGIALTPAGETFVRRARAVLHSIATLRTTAAAAPSSAPLVIAASPTLQAALAIPILAGLREHGVTVHTRLLGGSGSPEVADLVATGRADLGLCDSAVTTDLVAVPIGRAEVRLYSPAATDLPDRVTLADLGRVPLVLPTAGSARRATLDTFFAECAITPEVAVETDERHAWLAAVTHGIASCLWHSVETPRVPLPGVVARGFDPPIHRELTALHRADDETPLPRHLLEVLRQVGGLLSG
>NZ_CP009896.1|WP_038680548.1|3912081_3912528_-|SRPBCC-family-protein
MPAFAQTHETTIAAPPATVHALIDAFPEWTRWSPWEGLDPDLRRTYEGEGVGASYAWEGNKKAGEGRMTFTSITPEQVVVDLVFLKPFKAQNVVTFDLTPDGPGTRVAWTMSGERNLLFAVLGRLFFDKAIAKDFRRGLASLKAAAEG
>NZ_CP009896.1|WP_038680549.1|3912537_3913620_-|glycosyl-hydrolase
MSTILMVGTRKGLWVGTSPDRADWTFTGPHHDMEEVYSCLVDTRSPTPRLFAGASSSWLGPQLRWSDDLGATWHETPNGAIRFPEGAGATVARIWQLVPGVGDGVIHAGTEPGAVFTSTDGGESFRLEEGLWNHPHRPQWDAGYGGQAFHTVLPHPTDERSLTAALSTGGVYQTRDGGESWEPRNHGIRADFLPEDQRYPEFGQCVHKVTRHPSRPERLYAQNHGGVYRSDDEGGSWTSIGDSLPSDFGFPIVVHPHRPDTIWVFPLGGGDRRYPPDAKARVWRSDDAGESWTPYGSGLPDAFYVGVMRDALCVDSHDPAGLYLGARNGSVWASADDGESWRQIAADLPDVMSVKVGVSA
>NZ_CP009896.1|WP_038680551.1|3913746_3914052_+|hypothetical-protein
MTTLLVTLVLVPDRSDEVLARLRSEVAPWLRRLPGFVTSRWLLSPEHDRCTLVVELAGTEAVPVIEAALRPGTRDRARSWWCERMEDVEDLGLAVRPSVTP
>NZ_CP009896.1|WP_082003730.1|3914041_3916894_-|AAA-family-ATPase
MRSPRLVSRTAERARLHAAVDGVRDGRGGLWVLRGDPGVGKSRLAGALAAEAADAGLEVLSGRAVPSGTPTPLRPIGEALLAWLRTHEVPDDRLLAPYLPTLARLAPQLGPVAPDGASSVMLLGEGLLRLARAVPAPGIVLVVEDLHWADPETLALVEYLGDNAREVPLAVVATCRLHESPAANELLTALEWRRSAELVEVAPMADDDVAAVALACLGSEPPAEVVAWLQRYSAGYPLLVEEMLADLRDAGVLAEPTGDGGAWTLAGPLPVLVPRPFVRSVEGRLAEVGPQARQVATAAAMLGPELDWRLLAAALELSETEVAAALHDLRGQRLVVPVSGERFAFRHALTREAVLTGLLAPERARLAGLLAAALAALAGDADGAEDHLRLAELYEAAGDDERAVALWLATARDAIGRGALVSAGEALGRALARCTPGSSLETEVREAEVEVHALAGDVPRALAAGEVLTAELADEPGRLAAVRLRLARALLAGGSWDEAAAMLAAAAGHDPAQEEVLAARLALGREDGATAADRAAAALAAVGEDRPEIACEAWEVLGRAARARDYVAAEDAFEAGYRLADAHDLPLWRCRLLAALGSLDLAARRPTEDRLVAARRAALDVGAIATAARIEIELNLVRIRYLDLDEAMAAIDNATTMMTRLRLPDLATAYLLRAATHGLAGRADAMEADIATALDLPMDEGLRAVGVPGHVRSFVALAHARYDDAHAQLDLAMAHHRRSPSMPFSLRGFWALLETALGDDGAAAREEVRTGPQANSPHNWFALRYADAIALGRAGETAEAERVFADAEWGLPGREPWPELHARMLVARAAARDGWGTPEPWFRHVLDGLVGYGLTEAASACRVAMREAGFAVPRKAAGAERVPPHLQRLGVTARERDVLELVAAGLQNKQIADRLYLSVRTVETHVARLLQRTGSAERGELAAHLAPPTE
>NZ_CP009896.1|WP_038680554.1|3917051_3918965_+|hypothetical-protein
MRTQLLGLTTAALAVGTLSLGLTGSPASAVGGIDGGNISGSGDVPESVDVVSTGPGDAVAAWVRPVPGGDKVYAAIATNGVWSSPKAVTTNAVTAGNDVHVAANGNGDIAVVWSESLLGDERVRGARYLGNGTWDGSTPLNVQSDTVQTTDVAMDGAGRLHVAVGTTTQGVDRVQTALWPKGGAPTFATLGDHAYAPSIDVNPAGAALLSYYSSNNGGDVMVTRRTATTTWSTAVAVAWSGSVQKETQVGLADDGRGAVGFAGQDNGVYRASVAKVGATGLPGAPNILSGPGDVTAHRSLSVSPNGTLWATWTAFDGNDYLVRGAIAKPDAGFGSSGIVDPDTFTQTPHVALVSDRGAQVLAHNGADDLVLRHRTNPLFLFGEYDGGAADGPIAADMDREGNVVAVGVVENGLSSYVQADFLDVAGPTGTVTGPGPQVLAPSFAVTWSATDALSGVKSTDLLVRSAAWNAKSLGAPQVTGNDLTGAAKVFAGTRGATYCFAVQSVDKTANLGLRSAERCTSVPLDDRALAGKGWKRQAKAGHFDNTVSFTKQRGRVLKLKGVQAKRLALVATKSAKGGKVAVIWNGKVVRTISLKGKGARLVLPVATFGSVQGGTLKIKVISKTGRKVLIDGLVVAK
>NZ_CP009896.1|WP_038684953.1|3919032_3919884_+|EamA-family-transporter
MGVAVGLVLLGICSVQLGAGFAKRLFTDIEPNGVVWLRLATSAVVLLLWARPRLRGRSRDDWLVAARYGACLGAMNWGIYQSFSRIPIGVAVTIEFIGPLVLAAIGFRRPRDLGWVGLAALGVLLLGFERGHLDPLGVLYAVLAGAAWAGYILSSAATGRRWEGIDGLAVASLVAVVLLSPLLLTVDDSALADQRVLLLGAAVGLLSSVIPYSAELAALRTLPAATFGILMSMEPAAAALAGLAVVGEELAAVQWVAIACVVVASIGATRATRAKVHPDAAAG
>NZ_CP009896.1|WP_141267583.1|3919897_3920551_-|hypothetical-protein
MSLAALAMVAGGCGAAADEPQAVDAASAPQSAGVPINRSALDPAAKAAVTAPEVNAIDPQLPMTNASRFSAVVVGKVLGVADGPRFVDYEGDTEPGPDWVVLEVEPVAVLRGEERVGDPIHVRLTLSDREGLEKAIPPGTLAFVAAQPVDPADDQHLADPYAGVPAGKTRYIAGAPYVAVADGPGRIWYPVSGQSYDRPLTALVPGDLAPLLPAELR
>NZ_CP009896.1|WP_141267581.1|3920624_3921338_-|hypothetical-protein
MRITARRAGKEVSPMRPSATRLLRPTGLLKAGILAIVTVVVLPVAGHACNIGSRTDGRDATWCFTASMDGKPLMRDTARWALNNLVSSTVMTATPVASCDPAVNPGVDYRFADRDLGAGVYGSAECQVWSSSTVCGRYRINANRAEIVAALSSTDDMYSDGAEQSGERELNFKANWCHELGHTVTLEHHPVNFANRFSYYNGEGDRARDCMVRGHVEVSSNWLRYNAHHVSDVASRL
>NZ_CP009896.1|WP_038680561.1|3921447_3922383_+|alpha/beta-hydrolase
MSTSAPRPEQRVRSASIAFRDILSDDGTHVRAWTNDPDGVIDGPTVVLCNGLGTNPYLWPWLLDPACGVRVVSWNHRGVGGSERPADKKHVEIEHFVQDGLSVMDHFGIDSAVLMGWSMGVNTAFELTYRHPERVRGIFAMCGVPGDTFATMLGPLHLPRLLARAVTVNACRVAKHAGWAVNPIVRNLPMTPAVVRLLGRTGFMFPMADPEAASVGLQEFLTTPVDWYAHLAISTSRHPRVRLSKIQVPTMFVSATYDVLAGARDMASAARRLTDNGQDSAYVELRGSHFVQLEQPDRVHRLLLEFLEHVA
>NZ_CP009896.1|WP_038680562.1|3922379_3923558_+|PQQ-dependent-sugar-dehydrogenase
MTGRRRAGAAIAATAVLALLAAGCSQGGNESKVDVISTATAAPTGSVVDGKVIFTVDGVPDVVATVASGLDTPWGLDFLPDGRAVVTERTGRVLLVTAPEVSDGKPTDAEGKVVEAGRVAEARASGEAGLLGVAVSPGFAEDRLVYLYVCTDDDNRVVRATLDGDRLGPLEPVLTGIPTGTRHDGGRLAFGTDGYLYVSTGETGDAQLARDKKSLAGKILRITPDGEPAPDNPFGDAVWSWGHRNVEGLAFDDQGSLWASEFGDQTSDELNRILPGEDYGWPLAEGDAGPDRFTRPALTWPTDEASPSGLAFSGGYLWMAALRGERLWRVKVAGGEASDPTAYFTGQGEQTSYGRLRTVARAPDGRLWLTTSNRDGRGDPGADDDRILLIEP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_12

4061046-4061135

Orphan

Consensus_repeat	Method
GTTTCACCGCCTAGGCGGTGAAACTGCC	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP009896_12

>merge|NZ_CP009896|12|4061046-4061135|CRISPRCasFinder
GTTTCACCGCCTAGGCGGTGAAACTGCCCCTGAGCACAGGGAGTTCCGTAGGCCAACGCCCGGTTTCACCGCCTAGGCGGTGAAACTGCC

>NZ_CP009896|12|12|4061046-4061135|CRISPRCasFinder
GTTTCACCGCCTAGGCGGTGAAACTGCC	CCTGAGCACAGGGAGTTCCGTAGGCCAACGCCCG
GTTTCACCGCCTAGGCGGTGAAACTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038680736.1\|4067259_4067481_+\|acyl-CoA-carboxylase-subunit-epsilon	unknown	unknown	gnl\|CDD\|379386
NZ_CP009896.1\|WP_052138904.1\|4055206_4055776_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153228
NZ_CP009896.1\|WP_082003749.1\|4059828_4060614_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483
NZ_CP009896.1\|WP_038680738.1\|4067532_4068645_-\|epoxide-hydrolase	unknown	unknown	gnl\|CDD\|377658
NZ_CP009896.1\|WP_082003997.1\|4054150_4055041_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_CP009896.1\|WP_082003998.1\|4062854_4063148_-\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|294013
NZ_CP009896.1\|WP_038680740.1\|4069712_4071383_+\|DUF885-domain-containing-protein	unknown	unknown	gnl\|CDD\|377577
NZ_CP009896.1\|WP_052138905.1\|4055798_4058567_-\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NZ_CP009896.1\|WP_038680714.1\|4051709_4052276_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|366278
NZ_CP009896.1\|WP_082003748.1\|4052356_4053121_-\|class-E-sortase	unknown	unknown	gnl\|CDD\|320679
NZ_CP009896.1\|WP_141267567.1\|4053184_4053697_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038680724.1\|4060610_4061030_+\|CoA-binding-protein	unknown	unknown	gnl\|CDD\|224745
NZ_CP009896.1\|WP_038680732.1\|4064187_4064709_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|367615
NZ_CP009896.1\|WP_038680722.1\|4058660_4059830_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173847
NZ_CP009896.1\|WP_052138907.1\|4068699_4069716_+\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP009896.1\|WP_038680727.1\|4061639_4062827_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_CP009896.1\|WP_038680735.1\|4065649_4067263_+\|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl\|CDD\|227136
NZ_CP009896.1\|WP_038680730.1\|4063274_4064195_-\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
NZ_CP009896.1\|WP_038680718.1\|4053892_4054087_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_082003999.1\|4064754_4065693_-\|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl\|CDD\|223417

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038680740.1\|4069712_4071383_+\|DUF885-domain-containing-protein	gnl\|CDD\|377577	pfam05960, DUF885, Bacterial protein of unknown function (DUF885). This family consists of several hypothetical bacterial proteins several of which are putative membrane proteins.	4.70377e-176
NZ_CP009896.1\|WP_052138904.1\|4055206_4055776_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|153228	cd03134, GATase1_PfpI_like, A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. This group includes proteins similar to PfpI from P. furiosus. and PH1704 from Pyrococcus horikoshii. These enzymes are ATP-independent intracellular proteases and may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For PH1704, it is believed that this Cys together with a different His in one monomer and Glu (from an adjacent monomer) forms a different catalytic triad from the typical GATase1domain. PfpI is homooligomeric. Protease activity is only found for oligomeric forms of PH1704.	7.94543e-75
NZ_CP009896.1\|WP_082003749.1\|4059828_4060614_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	1.23532e-16
NZ_CP009896.1\|WP_038680738.1\|4067532_4068645_-\|epoxide-hydrolase	gnl\|CDD\|377658	pfam06441, EHN, Epoxide hydrolase N-terminus. This family represents the N-terminal region of the eukaryotic epoxide hydrolase protein. Epoxide hydrolases (EC:3.3.2.3) comprise a group of functionally related enzymes that catalyze the addition of water to oxirane compounds (epoxides), thereby usually generating vicinal trans-diols. EHs have been found in all types of living organisms, including mammals, invertebrates, plants, fungi and bacteria. In animals, the major interest in EH is directed towards their detoxification capacity for epoxides since they are important safeguards against the cytotoxic and genotoxic potential of oxirane derivatives that are often reactive electrophiles because of the high tension of the three-membered ring system and the strong polarization of the C--O bonds. This is of significant relevance because epoxides are frequent intermediary metabolites which arise during the biotransformation of foreign compounds. This family is often found in conjunction with pfam00561.	2.70301e-49
NZ_CP009896.1\|WP_082003997.1\|4054150_4055041_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	8.37759e-20
NZ_CP009896.1\|WP_082003998.1\|4062854_4063148_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|294013	cd00383, trans_reg_C, DNA-binding effector domain of two-component system response regulators. Bacteria and some eukaryotes use two-component signal transduction systems to detect and respond to changes in the environment. The systems consists of a sensor histidine kinase and a response regulator. The former autophosphorylates a histidine residue on detecting an external stimulus. The phosphate is then transferred to an invariant aspartate residue in a highly conserved receiver domain of the response regulator. Phosphorylation activates a variable effector domain of the response regulator, which triggers the cellular response. This C-terminal effector domain belongs to the winged helix-turn-helix family of transcriptional regulators and contains DNA and RNA polymerase binding sites. Several dimers or monomers bind head to tail to small tandem repeats upstream of the genes. The RNA polymerase binding sites interact with the alpha or sigma subunit of RNA polymerase.	1.98533e-25
NZ_CP009896.1\|WP_052138905.1\|4055798_4058567_-\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	2.83296e-13
NZ_CP009896.1\|WP_038680714.1\|4051709_4052276_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|366278	pfam00746, Gram_pos_anchor, LPXTG cell wall anchor motif.	0.003681
NZ_CP009896.1\|WP_082003748.1\|4052356_4053121_-\|class-E-sortase	gnl\|CDD\|320679	cd05830, Sortase_E, Sortase domain found in the class E family of sortases. Class E sortases are membrane-bound cysteine transpeptidases distributed in Gram-positive bacteria (mainly present in Actinobacteria). Genes encoding class A and E sortases are never found in the same organism, and similar to class A sortases, the genes encoding class E sortases are not positioned adjacent to genes encoding potential protein substrates, suggesting a housekeeping sortase function of class E sortases in some high G + C Gram-positive bacteria. Similar to class A sortase, class E sortases are capable of anchoring a large number of functionally distinct surface proteins containing a cell wall sorting signal to an amino group located on the bacterial cell wall. They recognize an LAXTG sorting signal, instead of the canonical LPXTG motif processed by class A sortases. The prototypical class E sortase from Corynebacterium diphtheria (named Cd-SrtF) is a non-polymerization sortase that is not required for pilus polymerization, and proceeds to complete the assembly process by anchoring the polymer to the cell wall peptidoglycan. Moreover, in Streptomyces coelicolor, one or both of Staphylococcus aureus SrtA homologs may function as class E sortase responsible for the cell wall anchoring of the long chaplin proteins (ChpA-C) containing an LAXTG sorting signal, which presumably mediate aerial hyphae formation. The family also includes some class E sortase homologs from Gram-negative and Archaebacterial species, but the functions of these enzymes are unknown.	2.59696e-48
NZ_CP009896.1\|WP_038680724.1\|4060610_4061030_+\|CoA-binding-protein	gnl\|CDD\|224745	COG1832, COG1832, Predicted CoA-binding protein [General function prediction only].	1.58024e-46
NZ_CP009896.1\|WP_038680732.1\|4064187_4064709_-\|PH-domain-containing-protein	gnl\|CDD\|367615	pfam03703, bPH_2, Bacterial PH domain. Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.	1.10362e-14
NZ_CP009896.1\|WP_038680722.1\|4058660_4059830_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	3.4292e-178
NZ_CP009896.1\|WP_052138907.1\|4068699_4069716_+\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	9.16227e-28
NZ_CP009896.1\|WP_038680727.1\|4061639_4062827_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	2.85465e-155
NZ_CP009896.1\|WP_038680735.1\|4065649_4067263_+\|acyl-CoA-carboxylase-subunit-beta	gnl\|CDD\|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP009896.1\|WP_038680730.1\|4063274_4064195_-\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	4.99871e-31
NZ_CP009896.1\|WP_038680736.1\|4067259_4067481_+\|acyl-CoA-carboxylase-subunit-epsilon	gnl\|CDD\|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	2.29802e-05
NZ_CP009896.1\|WP_082003999.1\|4064754_4065693_-\|biotin--[acetyl-CoA-carboxylase]-ligase	gnl\|CDD\|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	5.03053e-75

>NZ_CP009896.1|WP_038680724.1|4060610_4061030_+|CoA-binding-protein
MTTSAPAHQDPAAIDLMLDELTTWAVVGLSGNPDRTAYRIAELLQQRGKKIVPIHPSAPTVLGEQGYATLADVPFPVDVVDVFRRSEEAGVFADQAVEIGASGVWFQLGVVDEAAFERTRAAGVAMVMDTCPAIEWRRR
>NZ_CP009896.1|WP_082003749.1|4059828_4060614_+|TetR-family-transcriptional-regulator
MRVQLLRSLDGTQYHTRGTPFRRTTLVPVPAAATSRDRLVAAAFELFEGHGYDATTVDEIATRAGTGRSTFFRHFRGKEDVVLPDHEALLGRVGGRLATASPGGYEVALREAAGIVLAHYLAEGPTARARYRLASSVPAIRDREIASVQRYVRLFAQHIHRWLDTEPDGPLRAELVASAVVIAHNHVLRRWLRGETDDDAATAALLDHSLTLAVSLLRAPAEPGGTPTVVIAGDQADVEQVVQAVRAALGKKPATPGLGSS
>NZ_CP009896.1|WP_038680722.1|4058660_4059830_-|acyl-CoA-dehydrogenase
MSDFPMYALSEEHQAIREAVRAICDAKVAPFAAAVDEEARYPHEAAAALRAADFHAPHVPEEFGGAGADALATVLVIEEVARADVSASLIPAVNKLGSLPVMIGGSEELKKHYLGALARGEGGFSYCLSEPDAGSDAANQKTRAVRDGDDWILNGTKRWISNAGESEFYTVLATTDPDARTKGISAFVVEKSDAGVSFGAPEKKLGIKGSPTREVYLDNVRIPGDRIIGEEGKGFEYAMKTLDHTRITIAAQAVGVAQGALDYALSYAKERQQFGKSIADFQGLQFLLADMGMKVEAARQLTYAAAGRSERGDSDLTFFGAAAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRDAKITQIYEGTNQVQRIVMARQLLAGVQSEI
>NZ_CP009896.1|WP_052138905.1|4055798_4058567_-|OmpA-family-protein
MVFTFRKPGLTALAASVAAAAAVVVAAPTATAVPASSPCLDGTAPALASTVSCTSAGDYVLGVPAGTTDVDVAVVGAGGGAGYPARSHVGGNGAEVSGTLTLPAGTAYLKVVVGAAGAGNNHGYGYGGGGSGLMALDAGHNLIAKLAIAGAGGGGAYNGDGGNAGSAGTSENAALAAPGQPGIGGTGGAGGTGNYAAGSAGASNNPGSPTVAAGGAGGTYPNNSAGGSGGGGYGGGGGGATGNQGILNIYEAGGGGGSSLASGYLTNAAIGVKPGTGGVQLPGLVAGDGATGSVTLTFNGLARPGAPTGVTATPLDRAAKVSFTPPVSDGGSPITSYTVSASPGTATATCPGSPCTVEDLDNGTAYTFTVRATTENGDSAESEPSAPVTPATKPGAPTGVAAQPGDGEAQVTFTAPVSNGGAAITSYTVSASPGTATATCPGSPCTVEDLDNGTAYTFTVRATNDAGQSDPSASSAAVTPSGLPRVPTAVSAAPQDGAARVSFTPPLDNGGAAITSYTVSATPGTATVTCPGSPCTVEGLDNGTAYTFTVRAANANGDSGESDPSAAVTPVAVPGVPTHVAAEPGDGDADVFFTAPGKDGGSPITSYTVTAAPGDATATCPGSPCRVEGLTNGTAYTFTVHASNDQGDSAESDPSAAVTPTGVPGAPTGVSAKPGDRRLVVSFSAPGDGGSPITAYVVTVQPGGVTTTCAASPCTVGGLTNGKAYTVTVRATNAQGDSPESAPSTAATPVAPVAPVRWYRDPLTKAERQKLAPVPAHPARTRGPLRATKALYRTRNGTLAVPARQVRGHQLAARQGVQLTELFRFDSARLTPAGRQQLVVLARSLENVRALTCEGYADYAGSVRRERILSKQRAKAVCAFLEGKRPGLTTRAVGIGPERPAMIGGTAHRRDANRRVALLVRR
>NZ_CP009896.1|WP_052138904.1|4055206_4055776_+|type-1-glutamine-amidotransferase
MTDTENPLKIAFLVAPEGIERVELDEPWQAVADAGHQPVLVSTQPGEAQTFEHLDKSETRPIDVTVDATDPASYDALVLPGGVANPDALRTDEGAVAFVRAFMESAKPVAAICHAPWTLVEADVLRGRRLTSWPSLQTDLRNAGATWDDERVVVDGNLITSRSPDDLPAFIGALVEALEHGAGAAAAPA
>NZ_CP009896.1|WP_082003997.1|4054150_4055041_-|helix-turn-helix-transcriptional-regulator
MRIGRTGPRARAKVVRTAAEAISVDRVDFPFDMSYDVEPLGRICLCDIASGTIEGHGPAGSRPDDFGAGELFSLAPPERAYRGEVKQATYSITMLDPAVLGLVAAPAAGQDGVALLDHRPLDTAAGARVRAAIDHLDRAVLSDPGSAGNPLVVGAATRYLAAQVLAAFPSTSAAESAGDRRDAHPAALRRAIDYIEERAGSDLSPGEIAAAAHVSIRSLQLAFRRHLDTTPMRYVNDVRMRRVHGELSASTSGEGAGVAEIASRWGFVHQGHFGQAYRRAYDETPGATLRRDAPAG
>NZ_CP009896.1|WP_038680718.1|4053892_4054087_-|hypothetical-protein
MTDFVSPPPLSGPTPLAVARRRLECLACERMTAHVPGPATLGKDGEVLVRWWVCAECREAHTPG
>NZ_CP009896.1|WP_141267567.1|4053184_4053697_-|hypothetical-protein
MRRLLVLASAVTALLAVALCLPGAARADTDPYSPTVPTSCHVSVPTAVVGKRVVVRVSVEASDGQDPRGTVRLTLSSERWARTFRYDGTPLRIVGPRLAPGKHVARVHFVPKGDRYAGCRDQAPFGIGGDDAGPSEDLPNTGGPHLLVLLSGLGLVAAGGGLVEVGRRRA
>NZ_CP009896.1|WP_082003748.1|4052356_4053121_-|class-E-sortase
MTQTDLPDGEPERVRRRRSRPRHGSGSGGGTATATKPSTRKRISFWFGCGLILAGLAILCWVAWQFWGTNWQSHKRQGEVRQAIEKGWGDGQDVVRTDFGNATAILHVPRFGKDYAIPVLEGSSDEVLAAGVGHMEDTGEPGQVGNYVLAGHRVTHGEPFAEFPELEAGDKVVVETRAATYTYVLDTGGEDLIIPFTQTWVLDPKPVNPRSGGTQPPAEAGDQLITLLTCSEIFHTDNRSVVFGHLVETTPTNG
>NZ_CP009896.1|WP_038680714.1|4051709_4052276_-|LPXTG-cell-wall-anchor-domain-containing-protein
MLKKFVALATLAMACAVAPMATASADPYSPKVPTQTHIEVVVHGPGKPITLKVSASANYPTPPEGDIAIQVSAGGSAARNARALVAAPVFTTTVHFVDDVVSVEGPRLPKGTYLARAALSPDDTDTFLPSSATTDFRIGAGTPDQDDNDGLPNTGGPDLLWLLLGGGLVVAGAGGVGYGRRRTASVAV
>NZ_CP009896.1|WP_038680727.1|4061639_4062827_-|5-(carboxyamino)imidazole-ribonucleotide-synthase
MSSTELAPRVAVIGGGQLARMMAQPAVALGVPLRLLAEAEGVSAAQVIPDQQVGDYRDLATLRAITQGCSVVTFDHEHVPTEHLRALAADGVIAHPGPEALVHAQDKIVMREAMARLDAPQPRWAVVASEAEVEAFGLPCVLKVSRGGYDGKGVWMVRTLADAAEPLAAAAAAADRGVRLLAEELVDFRRELSALVARSPSGQAAAYPVVATLQVDGVCREVVAPAPDLDPAAAAAAQQLALRIAGELDVTGILAVELFEAVDAEGRTRILINELAMRPHNTGHWTQDGAVTSQFENHLRAALDLPLGSPEPRARWTVMVNILGGDDPDVGRLYDGYPHALARDPHLRVHLYGKELRPGRKVGHVNVYGDDLDDCLERARHAAAWFRGDLGNDSD
>NZ_CP009896.1|WP_082003998.1|4062854_4063148_-|winged-helix-turn-helix-transcriptional-regulator
MTRRTWRGDREILLSRKEFDLVHALIVRAGSVVSREELMRDVWGVTFWTSSKTIDVHLGWVRRKLGDDTRQPHLITTIRGQGLRFEVATATEATGSA
>NZ_CP009896.1|WP_038680730.1|4063274_4064195_-|adenylate/guanylate-cyclase-domain-containing-protein
MSDEPELTAADVAERAGIPLDQARRLFRTLGFAEHGDERAYTEADVEAMRLMVDILGEGVIDLDVALNVTRGVGITMARLADWEVGELVQHVDEATALREGGDAAWVLARLGERFEGLLVYAWRRHLDAAIARMESVRALDDDPHTTDLSVGFADIVGFTALSNEVSRERIGELVEVFESRCGDVIARDGGRLIKSMGDAVLFVNDDPMAAFATAEGIINVIGRDPRMPDVRVGLATGGVVLRLGDVFGPPVNLAARLTQVARRNRIIVDHATADLLPADKIESRPLPARPVRGFGVVEPVAVRRA
>NZ_CP009896.1|WP_038680732.1|4064187_4064709_-|PH-domain-containing-protein
MAISKKLLNPGERLIISTRQHPKALFVPILALIVFLAIAVVAQVKLENDGFQRVLTLIVWVLAILGILWFTVRPFLVWLTTVHAFTDRRLITRNGIVTRRGHDIPLARVSDISIEINLIDRPFGCGSLIIADASTFGTVRLNDIPHVEATQRQLNELLHDLHARPDARRDEGV
>NZ_CP009896.1|WP_082003999.1|4064754_4065693_-|biotin--[acetyl-CoA-carboxylase]-ligase
MSICWSSADCGWAVTWPPRTPATPGFPQGVCCARVVPVTLGPTQPPVRGPLDAARLAEVSTLTPDLAFELLPEAPSTNEVAAERARAGAHEGLVVVADHQVAGRGRLDRVWQTPPGTAVTFSLLLRPTVPPASWPWLPLLVGHNVAKALTSLGYDARVKWPNDVLLDGDRKVSGILVERVETPTGPAAIVGVGINVSTTADELPVATATSLAISAPGAPDRTQVLLQVVAAIREGYDVWQAGGEQGTTRLATSYRSHCATLGREVRVELPGGGELLGRATDIDDDGRLVVETPDGPERVGAGDVIHVRATDA
>NZ_CP009896.1|WP_038680735.1|4065649_4067263_+|acyl-CoA-carboxylase-subunit-beta
MTAQPQSADDQQIDIHTTAGKLADLERRTDEAVHAPAAKAQEKQHAKGRKTARERIELLFDEGSFVELDEFARHRSTAFGLEKTRPYGDGVITGYGTIDGRQVCVFSQDFTVFGGSLGEVYGEKITKVMDLAIKSGCPIIGINEGAGARIQEGVVSLGLYGEIFKRNVHASGVIPQISLIMGNCAGGHVYSPAVTDFTIMVDQTSAMFITGPDVIKTVTGEDVTMEELGGARAHNTKSGNAHYMASDEEDALEYVKALISFLPQNNLDEAPSYDEPADLEPNEADIALDTLIPDSPNQPYDMHDVIATIVDDADFLEVQALFAPNIITGYGRVEGRPVGIVANQPMQFAGTLDIDASEKAARFVRFCDAFNIPVLTFVDVPGFLPGVDQEHLGIIRRGAKLIYAYAEATVPLVTIITRKAYGGAYDVMGSKHLGADINLSWPTGQIAVMGAQGAANIVHRRTLAEVEKAGGDVEAKRAELIDEYETTLANPYIAAERGYVDGVIMPRETRAEVVKALRLLRTKRETLPPKKHGNIPL
>NZ_CP009896.1|WP_038680736.1|4067259_4067481_+|acyl-CoA-carboxylase-subunit-epsilon
MTGDETLLRIVTPDTTPEEVAAIVAVLSSLGGGAPAPEPPRSEWANPARGARIAPGTTLSHGRGAWRASGLPR
>NZ_CP009896.1|WP_038680738.1|4067532_4068645_-|epoxide-hydrolase
MNQITPFVIDIPQTDLDDLRDRLDRTRFAPAVPGDSWEYGTPESYLRAMVERWKDLDWRAVEARLNAYDGFVTEVDGQRIHFLHVRSKHADATPLLLAHTYPGSQLDFLDMIEPLVDPEAHGGTADQAFHLVIPSMPGFGWSTPVADTGWTMKRVAAAYDVLMRRLGYDSYGIHGSDGGAMVGRELAVANPEGFRGAHVLHLFSFPSGDPAEFEGFGPKEYAALEHMQWFQSVGGYNQMNGTRPQTVAAGLADSPVAVLAYSELFESFGNGTSLVAPEQVLAQATLYWLTNTYGSAARYHYEEQHSGAEPVVSTGRLGVAVFKDDFQTIRSLADRDNANIDHWSEFPRGGHFAAQEVPEDVVADLRVFFA
>NZ_CP009896.1|WP_052138907.1|4068699_4069716_+|WYL-domain-containing-protein
MQKTSGRVLALLGLLQSRVEWTAPELARRLDVTERTVRNDVARLRELGYPVEALRGRAGHYRLGVGAKLPPLLLDDEEAVAVAVGLRTVTGVAGFEESGGRALTKLEHVLPDRLRRQLASLREATEAGPVNTDSNVEDPEVEPGVLTEIAAAVRDHRGLRAFYGEAGERIEIEPYKLVAWQRRWFVVGRSPDTGDWAPYRVDWMTLRLPGGRAFTPAPLPGDLTELVVREVARTGWAVHARLVIDAPADEVLARINPAVGVVEPRPDGRSVLVTGGDSLEVVAVWIGMLGLDFTVESPPALVDHLRVLAQRYDRAVRQGDDRGANRMPLSDPPPRLGP
>NZ_CP009896.1|WP_038680740.1|4069712_4071383_+|DUF885-domain-containing-protein
MTRRVDARTDQYVEDLAALDPITATFAGIAGHDDELPDLSPDGFAATEELHRRALADVAALEAADEREQVAQDAFLERVGLSVERADAGVERSEFSVISSALHAVREVFDLMPTETTEHWEAIRARLAAVPAALDGYRTTLTEEAAAGRVSAKRQYAEVAGQVRGWTGQEGAAGDYFERAVADAPAPLRDHLAEAARTASTAYAEFGRFVETDLLPQGREVDGVGRERYQLASRYFLGASVDLEETYRWGWDELKRIEDDMAATAGRIVPGGSVADAVAVLDADPARDCGSREAFQAWMQERSDTILADFDGLHFDIAEPIRTLQCKVAPVNDGGAWYTPPSEDFSRPGTMWFSFTDANERFSTWRETTTVFHEGVPGHHLQCAQVVHRADLLNRWQRLLCWVSGHGEGWALYAERLMDELGYFADPGERLGFLDMQGFRAARVVVDIGVHLGLTVPADNPFGWRPGETWNADLAYEFMRAHSRMDDGSLRFEVNRYLGWPGQAPSYKVGERIWLEARAAAQARHGAAFDLKAFHTAALDLGSLGLDPLQAALARL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_13

4726849-4726965

Orphan

Consensus_repeat	Method
CGGCAGTTTCACCGCCTAGGCGGTGAAACTGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_13

>merge|NZ_CP009896|13|4726849-4726965|CRISPRCasFinder
CGGCAGTTTCACCGCCTAGGCGGTGAAACTGCCGAAGCGAGCGCACGAAACTGGTCGTGGGCCCACGGAGTTCCCTGTGCCCACCGGCAGTTTCACCGCCTAAGCGGTGAAACTGCC

>NZ_CP009896|13|13|4726849-4726965|CRISPRCasFinder
CGGCAGTTTCACCGCCTAGGCGGTGAAACTGCC	GAAGCGAGCGCACGAAACTGGTCGTGGGCCCACGGAGTTCCCTGTGCCCAC
CGGCAGTTTCACCGCCTAAGCGGTGAAACTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038681762.1\|4733992_4735528_-\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377939
NZ_CP009896.1\|WP_038681769.1\|4737507_4738176_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl\|CDD\|235140
NZ_CP009896.1\|WP_052139026.1\|4723764_4724367_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378968
NZ_CP009896.1\|WP_052139024.1\|4718329_4719721_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|226906
NZ_CP009896.1\|WP_141267378.1\|4725773_4726817_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038681758.1\|4730933_4732259_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|223609
NZ_CP009896.1\|WP_038681766.1\|4736112_4737411_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|236821
NZ_CP009896.1\|WP_052139028.1\|4738399_4739428_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378976
NZ_CP009896.1\|WP_038685331.1\|4715747_4716812_-\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NZ_CP009896.1\|WP_038681770.1\|4738172_4738418_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl\|CDD\|235659
NZ_CP009896.1\|WP_052139025.1\|4723399_4723765_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380033
NZ_CP009896.1\|WP_038681764.1\|4735657_4736116_+\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|238612
NZ_CP009896.1\|WP_052139023.1\|4716835_4718326_-\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236113
NZ_CP009896.1\|WP_141267377.1\|4722756_4723413_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235615
NZ_CP009896.1\|WP_038681760.1\|4732260_4733892_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|223568
NZ_CP009896.1\|WP_052139027.1\|4729493_4730921_+\|DUF1906-domain-containing-protein	unknown	unknown	gnl\|CDD\|119380
NZ_CP009896.1\|WP_038681751.1\|4724436_4725696_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP009896.1\|WP_038681740.1\|4721359_4722712_-\|dipeptidase	unknown	unknown	gnl\|CDD\|236127
NZ_CP009896.1\|WP_038681738.1\|4719805_4721344_+\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038681756.1\|4726991_4729265_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038681762.1\|4733992_4735528_-\|PucR-family-transcriptional-regulator	gnl\|CDD\|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	2.6746e-26
NZ_CP009896.1\|WP_052139026.1\|4723764_4724367_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|378968	pfam12840, HTH_20, Helix-turn-helix domain. This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.	1.9009e-12
NZ_CP009896.1\|WP_052139024.1\|4718329_4719721_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|226906	COG4529, COG4529, Uncharacterized protein conserved in bacteria [Function unknown].	1.66959e-83
NZ_CP009896.1\|WP_038681740.1\|4721359_4722712_-\|dipeptidase	gnl\|CDD\|236127	PRK07907, PRK07907, hypothetical protein; Provisional.	0
NZ_CP009896.1\|WP_052139023.1\|4716835_4718326_-\|amidophosphoribosyltransferase	gnl\|CDD\|236113	PRK07847, PRK07847, amidophosphoribosyltransferase; Provisional.	0
NZ_CP009896.1\|WP_038681766.1\|4736112_4737411_+\|cytosine-permease	gnl\|CDD\|236821	PRK11017, codB, cytosine permease; Provisional.	2.49434e-119
NZ_CP009896.1\|WP_052139028.1\|4738399_4739428_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	3.64698e-27
NZ_CP009896.1\|WP_038681760.1\|4732260_4733892_-\|NUDIX-hydrolase	gnl\|CDD\|223568	COG0494, MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes [DNA replication, recombination, and repair / General function prediction only].	0.00198248
NZ_CP009896.1\|WP_038681770.1\|4738172_4738418_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl\|CDD\|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	4.20981e-40
NZ_CP009896.1\|WP_038685331.1\|4715747_4716812_-\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	3.28008e-176
NZ_CP009896.1\|WP_038681764.1\|4735657_4736116_+\|nucleoside-deaminase	gnl\|CDD\|238612	cd01285, nucleoside_deaminase, Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on the substrate. The functional enzyme is a homodimer. Cytosine deaminase catalyzes the deamination of cytosine to uracil and ammonia and is a member of the pyrimidine salvage pathway. Cytosine deaminase is found in bacteria and fungi but is not present in mammals; for this reason, the enzyme is currently of interest for antimicrobial drug design and gene therapy applications against tumors. Some members of this family are tRNA-specific adenosine deaminases that generate inosine at the first position of their anticodon (position 34) of specific tRNAs; this modification is thought to enlarge the codon recognition capacity during protein synthesis. Other members of the family are guanine deaminases which deaminate guanine to xanthine as part of the utilization of guanine as a nitrogen source.	3.71434e-35
NZ_CP009896.1\|WP_038681758.1\|4730933_4732259_-\|radical-SAM-protein	gnl\|CDD\|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	8.1335e-11
NZ_CP009896.1\|WP_141267377.1\|4722756_4723413_+\|hypothetical-protein	gnl\|CDD\|235615	PRK05812, secD, preprotein translocase subunit SecD; Reviewed.	1.59303e-20
NZ_CP009896.1\|WP_038681769.1\|4737507_4738176_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	4.94719e-143
NZ_CP009896.1\|WP_052139027.1\|4729493_4730921_+\|DUF1906-domain-containing-protein	gnl\|CDD\|119380	cd06418, GH25_BacA-like, BacA is a bacterial lysin from Enterococcus faecalis that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. BacA is homologous to the YbfG and YkuG lysins of Bacillus subtilis. BacA has a C-terminal catalytic glycosyl hydrolase family 25 (GH25) domain and an N-terminal peptidoglycan-binding domain comprised of three alpha helices which is similar to a domain found in matrixins.	2.26907e-43
NZ_CP009896.1\|WP_038681751.1\|4724436_4725696_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.92311e-44
NZ_CP009896.1\|WP_052139025.1\|4723399_4723765_-\|hypothetical-protein	gnl\|CDD\|380033	pfam17844, SCP_3, Bacterial SCP ortholog. This domain is found in MSMEG_5817 gene product from M. smegmatis. It has been shown to be vital for mycobacterial survival within host macrophages. Crystal structure revealed a Rossmann-like fold alpha/beta two-layer sandwich forming a highly hydrophobic interface cavity and with high structural homology to the SCP family. Hence, it has been suggested that this domain may be involved in the interaction of apolar ligands through its hydrophobic cavity. Alanine-scanning mutagenesis of the hydrophobic cavity of MSMEG_5817 protein demonstrated that the conserved Val82 residue plays an important role in ligand binding.	3.96248e-43
NZ_CP009896.1\|WP_038681756.1\|4726991_4729265_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0

>NZ_CP009896.1|WP_141267378.1|4725773_4726817_+|hypothetical-protein
MLPPRRCAVAVVGLLALAPALVACGGDTGVQAGDVVPARDDAQFAGTGNESMLALPIGRLEITLGKPTDRLSADDTRQIEALDAPDGGTFVPITWQYDASTFGRYAAFIDTPDSPVVDLVADGARYRIPPPDDSGKGSTSFYVVVAGPGKDPRLEVDFDGVTQSVDLTTGDRDAGAAEALYDLPSPKTKRTDCTGTIEYGRKLVGASSFTCATTRPVRLPYAGDSWAEDGQSWLALTVRTTLGRWNEVAKDLKSGGVYYATGVAGSFRLGDIEATKAYQDNEQTTCPSTTSGSCTTEFHVIFAVGDKVPKKLTVEQDYTLLLTSAWGTGTDGEQNLDLPVTTTTTLK
>NZ_CP009896.1|WP_038681751.1|4724436_4725696_+|MFS-transporter
MPAFRALARNHDFTALWVGATVAELGSRVTIFAAPLVAYALTGSPLWAAAAEGVFLTGMVAALLPAGVLADRWHRLRLMRISLGTGFALYASLAVAGAAGALTLPHLLVVLLVTGVVTGLFGPAEYAAIRTIVSDEQLPTALSQQQARQHVAALLGGPLGGALYGVARWAPFAADAVTYALGWLLLGRVRADLSARPDPERTRSRPLRDVGDGIRFVWRRPFLRVLLFWSPTVNLTINALFFVALLRLIEADFSAAQIGLTQAAIGGFGVLGAIVAPVLVERFATGTLTVLVAWSWVPLAVPLALWNHPLSMALAGALGMFLNPAGNAGVGAYRMATTPPELIGRVQSAMQFVSMATMPLAPALAGLLLAVLGGRDAILALAVLTGLAALAPTLSRSVRTVPRPADWPRHDAGLTLAGP
>NZ_CP009896.1|WP_052139026.1|4723764_4724367_-|helix-turn-helix-transcriptional-regulator
MVLYDDPRILRAIAHPTRNRVLHELSAAGSLRAADIARRIDVPANQASFHLRQLAKYGLVEEDPEAARDRRDRVWRLVDPQGIRFRTSDMLAQPGGQAAYAVFQRNAVEWGRHLVERAFTPPDDGARPERSISEWALLLTPGEAEELMNEIADLVDRRRLAAQRPGSGGADDERETYSVYQLIQPYPGLPVDQPTEENDS
>NZ_CP009896.1|WP_052139025.1|4723399_4723765_-|hypothetical-protein
MPARLRPADPALVAEALARVEAGTAERADLRLLTKHYLALLETRAPGRSVEVRVPPYAAVQVIEGVRHTRGTPPAVVETDAATWIELATGRLGWDAALDGARVQASGERTDLTPYLPLSAS
>NZ_CP009896.1|WP_141267377.1|4722756_4723413_+|hypothetical-protein
MALSRMLQATTVAAALTLALSACGSGDDGDATDKDGSGADAAASSPAPGDSPAAGDEASDDASDDAAPSGPVQFRRVLEATGIPADGAESTPLPEDCSDVPAGQPKAGAETIACDESGIVYRLAPAEITGGVESAEAEKPANLTDWVVSLRFDAQAATAFGALTRELAGTNKLLAIVLDGEVISAPTIQDAVEDGRVQIGGTFTEEQATTIAGQLTKR
>NZ_CP009896.1|WP_038681740.1|4721359_4722712_-|dipeptidase
MTGPVSTTDLRARLAELLPGVRSDLEALVRIQSVSADPDRLDQVEVSARATADLFAAEGVDVQIVRAFDGAPPAVIGEKKGPAGAPTVLLYAHHDVQPENDHAEWDSAPYEPTERNGRLYGRGVADDKGGIMTHVAALRMLGDELPVTVRLFIEGEEEVASATLPQLLEKYVDELRSDVIVIADSGNWDIGVPALTTSLRGLVRVNVEVRTLTHAVHQGMWGGLVPDALITLSRLIASLHDDAGQVAVAGLHSGPAADVDYPEERLRAESGVAEGVQWVGSGPAVERLWTQPALSVIGLDAPKVDGSSNTLIPSARARLALRTAPGETSENALACLKAHLEKHVPWGAQLTVDVVDTGEPIALDVNGPAYDAARSAFAEAWDGTAPVDMGVGGSIPFIAEFLETFPQAAVLVTGVEDPDTRAHGPNEGLHLAEFEKVLLAEALLLRNLGA
>NZ_CP009896.1|WP_038681738.1|4719805_4721344_+|PQQ-binding-like-beta-propeller-repeat-protein
MLLPRVLAGLLLAALLTACDAGDDPGPRPAPALPELAPAWTAAGVTGDRAWLVDDLLVVAGKATLTGLDRATGAVRWTRSLAPGICTTALAPNPDSLLALVVQRTAKPQTCAAAALVDLHDGALRWRKDLRDQHPSHWDDARYDGAGAGTKVVAVTDTVIGAALRLDVRDGAVLSRSDDAEYTTDGPHLVALTSLNLRRSPTIETRATVTETDTGRRVRTFRTRDASNLFPVQAAPLVVGTERGQWGSDLYVEHGGQVRVVGRGLGLFTATVDDRVVQGYDGALVVSDAGTGEELSAQPLDPQEEVAGVAGDAVITYDRVPGWLPDAPAVLRRLPLDGSGEPVVLGRVRGAALLVADGVAYTAGRDGMRAYRLPADGTPTSAYLDRLAWREGDLRPAEVFDACRAVSGETLAQVGLAADERVDASCWWGGGRRFSVAVEAGLPEAPAPAREDGAEDVPGLGDSAWLVERSRALELTVRLRNVTVRVTATATDARPGVLEAAREVLAALEDRD
>NZ_CP009896.1|WP_052139024.1|4718329_4719721_-|FAD-dependent-oxidoreductase
MTSTQAAAPTPAPLRARTRVAVIGGGASGVLTAINLLVRSDDPGLEVVVHEASGIVGRGIAYGTNDQRHLLNVRARHMSAFPDAPSDLLDWALRTGRGSDPQAFLPRADYAIYLQDRLADVADDRLRIRAGRVRDVVPTATGFDVVTERSTAPADAVVLCHGNQPPRPLADLPDAPWHIGNPWQLGRLRALPADARVVVVGTGLTAVDTVITLLEDGPERHVTMLSRSGTLPKPHVEQAHTAWVTKVPDDAVTADQVAEAVAEECRAAAERGVGWRAVVDGLRPLTQELWRRLPHDERRRFLDVHVREWEVRRHRMAPEVALRLQRYRYDGRLTIRPGTLHEVDDLGERCAVTAAPGATPIPADAVVNCTGPLADVRRSADPLIQALVARGTVAPDPLALGIDSTVDGRVVDASGAVVDGLYVVGPPRKGTLWESTAIPEIRAQAAQVASAVVERTSRSIAAN
>NZ_CP009896.1|WP_052139023.1|4716835_4718326_-|amidophosphoribosyltransferase
MRPIAGTLKPVCGVFGVWAPGEDVAKLTYFGLYSLQHRGQESAGISVSNGRQILVYKDMGLVSQVFDENTLESFAGHLAVGHCRYSTTGASTWQNAQPTFRPTEDGSIALGHNGNLINTAALAEMVKELPSDDGELDIHARDLEASTNDTSLVTALLAHHPDQSLEARALELLPQVEGAFSFVFMNENTLYAARDPEGIRPLVLGRLDRGWVVASEDAALATIGASVIREVEPGELIVIDEDGLRSHKFAEPRRKGCVFEYVYLARPDATIAGRSVHEARVEMGRQLAREFPVEADLVIPVPESGTPAASGYALESGIPFGQGFVKNAYVGRTFIQPSQTLRQLGIRLKLNALEHMIRGKRVVVVDDSIVRGNTQRAQVRMLREAGALEVHVRISSPPVKWPCFYGIDFATRAELIANGLDAAEIAASVGADSLGYISLDGMVEATGQPQATLCTACFTGDYPIELPDESLLGKHLLEATLAPSTHGEALPVFNNP
>NZ_CP009896.1|WP_038685331.1|4715747_4716812_-|phosphoribosylformylglycinamidine-cyclo-ligase
MVADNAYARAGVDIEAADRAVDLMKEWVEKARRPEMRGGLGGFAGLFDASALLSYRRPLLATSTDGVGTKVAVAQMVDKHDTIGFDLVGMVVDDLVVCGAEPLFMTDYIATGKVVPERIAAIVKGIAEACVEAGCALVGGETAEHPGLLAPDEYDVAGATTGVVEADALLGASRVREGDVVIAMAASGLHSNGYSLARHVFFTQAGWSVERHVDELGRTLGEELLEPTRLYTKPCLTIARETETHAMAHVTGGGLANNLARVMPPELKATLDRATWTPGPVFDLVRRLGDVAQPDLEATLNCGVGMVALVAPDAVDGALARLAESGIDSWVAGDVTVDPDQKGTVELVGQHPGW
>NZ_CP009896.1|WP_038681756.1|4726991_4729265_-|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MADTASAPARSTLDTVAVAAGDPEREQPWAELGLKADEYDRIKEILGRRPTSSELAMYSVMWSEHCSYKSSKVHLKQFGAIPQETPIGPMLAGIGENAGVIDIGQGYAVSFKVESHNHPSYVEPYQGAATGVGGIVRDIIAMGARPVAVMDPLRFGPLDADDTHRVLPGIVAGVGGYGNCLGLPNIGGEAVFDETYLGNPLVNALCVGVLRHEDLHLAKASGTGNRVILYGARTGGDGIGGVSVLASETFDADGPAKRPSVQVGDPFMEKLLIECTLELFRAGVVNGIQDLGGAGLSCATSELASAGDGGMRCELDRVPLRDSTLSPEEILMSESQERMMAVVEPGDVAAFLAICAKWDVEAVDIGEVTDTGRLEITWHGETVVDVPPRSVAHDGPTYQRPFARPDWQDGLQADGAEALARPGTGEELRATLLQMVASPNLCDKSWITDQYDRYVQGNTVLAQPADSGMVRVDEETHLGVSVATDCNGRFAKLDPYAGAQLALAEAYRNVATGGALPLAVSDCLNFGSPEDTDVMWQFAEACRGLKDACLELGIPVTGGNVSLYNQTGETAILPTPVVAVLGVIDDVRRRTPSSFQAAGERVVLLGTSREELSGSEWAHVVHGHLGGRPPQVDLAAERSLARLLKDLVGIATSAHDLSDGGLAQALAEAAMVSGIGARVALDGDAFVGLFAESAARALVTVATDDLAELRALCARHDVPLTELGTTGGDALVVEGQFDVPLAELRAAWTATLPAALG
>NZ_CP009896.1|WP_052139027.1|4729493_4730921_+|DUF1906-domain-containing-protein
MPARPVTVRSPRRLRASLAGVATLTTGALAVVVTLALLGPLRPDAAPTTDAPVDLSAKSTNPVTPGNFTGYGFDQCLAPTQKKMDAWLEHSPFLAVGIYISGNSRACRSQPNLTPTWVSTQLAKGWRLLPISLGPQSSCVGRFPRYGAKIDPTISNVSTNSYAAARAQGKAEADTAVAAAQALGIVPGSTLWYDLEGWSDYRNATCRESALAFLTKWTQRIRNRGYVSGVYSSAGSGMKILDDARAAKRADVVVPDQIWVARWDNVANTSTSYLRADGWLPGRRMKQYQGGHNETWGGVTINIDRNYLDLGNSTPAAETHCGGVRVDLTYRKVMPRSGSYRPDPTLVKALQCLLREKAGYTGALTGNFNKKTRATAQAWQRRTGTGVSTKWRKKDWITLHAAGARPVLKIGSRGSDVRRVQRALQIAVPGARVVVNGVYDARTASAVSAYRKQVGLPAYGIVHSATWAKLAAGAR
>NZ_CP009896.1|WP_038681758.1|4730933_4732259_-|radical-SAM-protein
MAADRLTGRLVPGGPWERFGRYNAYHVVRDDGAALVVRAHAGELVPGSTEDLVAFLSGLGGALPRGPMTLELDPTYACASVSCGEVCFSAEYRAQRPRASIGSEALRQAISAFADAGGRVLRFDGGGDPLLHPDVRSGAAVRLGAELGLRTTILTSGDLLPATDWRAVVDADCYLRVSLNAHSTPVRRRVHGNKVDMDRLWHVLARACEHARAVGRTPVGATFLLTPDNYAEVALAARRAREVGVRHFSVRRVLGPDALRRPFDPAARAALPELLQEVAELDADAFRVFVPARDVAESDLSPRAGDIAATSCWQSVFKTVLEPAAGPDDVRVQLCGRYRGSGVGQAMQLPPLAADADPATWDRAWARSFEVYPVSRPDLIRTCVSCIDRGFIQMMDRLVAFTAMGARPFTIEHLWLDPESLARCEPGIVVDDDAGLAIAPA
>NZ_CP009896.1|WP_038681760.1|4732260_4733892_-|NUDIX-hydrolase
MADGLRKTALAPVRTATTLRDEVRENERLRLLLTTGAFLIPATIIWIFEEIPLAWRVVGTLALLLTASLVGIVALSAQLRQQDRLEAEPLPADLGSIPAAARAHREVRDGDPLLLAAHRADFVGLTYKSLSDMLDEVNARGAQLDALTTACLYVYALPVLEQLHPTLRHSSGLLPEWSRSIENAIEGLRRAAPALRELDLVLLDAEPAFTMSRVWTADDAGSGVHHLRWTPVVAGTEPKDMPTLRFESSSGDVDGAELYQAFSRFSEDLISRRAVRRFPLVRADLGYERADVAGLVELLAKISTHPIMRRDDVSFDVSITAPVALLGERTALKPWEVRTFYEAYLDPAGSVVSFTAEMAPRRQQATIRVDDGAHGEVRTVPVTEKHRLAAFALMTLPGAEPSVLLVDKPKGIWALDVPGGKVGVDDADWRATIRRELVEELALVLPPDANLRQVAWSYDPKSQKEGVPVLSVYAAHLLEPELASYARSFLVGKDGVAARRTLALPAADLLRRKAAQGADNSWAEPLCHAPRRAFEAVVRMAGR
>NZ_CP009896.1|WP_038681762.1|4733992_4735528_-|PucR-family-transcriptional-regulator
MGASLAEVLSLPSFRAAGTEVVHGDVGRVQVRWVHSSEVFEMGSLLAGGEVLLTSGLGLHGRTAEHLGAYVDQLADAGVAAIGLEVGRTFFTVPDSILEAVRRRDVPLLVFHRVVPFERMVEDFHELLVRRKVEAGTGDAGWRALTQTVIEGRGLRALLDETSRLAGCAVELRDPDGQTVERSRIASVSGDAAVQVQVRGEAGVHGTLRLLGAETSHRVRVAEAAGIAVALELGRGAGGGHRPGPQQSLVADLVAGVVVSRADVLHRLGDLGWPPLEGRHLVVAAIEVDAAVPLTDAVAATERALVDDGRGDPAVLVGTSGGHVVVVHRGGRRAVPAQVRDDLTAAAERLAAQLPGRVLLGATTPVADPGDLSAAVGRARQVVRTARRYGRRTGVVMERDVAPHRLVTRAVDPQVLSDFVREQIGPLIDHDREHRSELLRTLDAYLACSLSKARTADLLGLRRQSLYDRLARIERLLGVSLDEADHRTGLGLALLGWRMRTGLDPQVGFGG
>NZ_CP009896.1|WP_038681764.1|4735657_4736116_+|nucleoside-deaminase
MITDDDRRYLDLAIEQAQLGWEEGGIPIGAALVHDGQVLAVGRNRRIQLGSAIRHGETDCIENAGRLPASVYRRSTLYTTLSPCFMCAGTSVLYDIPRIVVGENVSFQASEEWLRSRGVVVDVVDDPVCRALMEKMMSERPELWAEDIGEEA
>NZ_CP009896.1|WP_038681766.1|4736112_4737411_+|cytosine-permease
MSAPAGQESPVAAEAVVDPDYPVTPVPLHARKSFLSLAVVLLGFTVFTPTMLAGAQLGSAFALGDLLRVILLGSLVLGTYVALLGWIGAKTGLTTVVMARYVLGYRGSKLGSILLGGTQIGWYGVVIGTIGDLTATAFEWESDVAKAAVMIATSVLMCLTACYGYRGMYWVSAISTPLILILAFWVLFRSLDEVGGWSGLADVQPNATMTTAVAITTVVGTFVSAGTQAPNWTRFARSGNQALLACVIGFLIGNGLMIFFGATGAMTFGQGDFVLVLYDLGLVTWGLVLLFGNLWKSNADTAYAFGVAGAELFEKPKKTPFVIYGSVIGTVLALVGVQNHLVDYLVLLGVFIPPLGGVVIGDYFARWRHGGMPEGERLPALNIPNLAVYAVASGVAWIAKEAEFGVPPVIGVVLAALGSYAVGRAGLNRRLS
>NZ_CP009896.1|WP_038681769.1|4737507_4738176_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKVGVVTFPGSLDDVDAQRAVRIGGNEAVALWHGDADLKGVDAIVLPGGFSYGDYLRCGAISRFAPVMDKVVEAAGAGMPVLGICNGFQILCESHLLPGALIRNDHRKFVCRDQLLRIENNRTPWTSAYEQGQEIRIVLKNGEGGFVADAATLERIEGEGQVVARYLELNPNGSLNDIAGVTNERGNVVGLMPHPEHAVEELTGSGLDGLGFFTSLVEHTFA
>NZ_CP009896.1|WP_038681770.1|4738172_4738418_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MARVVVAVMPKPEILDPQGKAVQGALPRLGFTGVTDVRQGKRFEIELDGEVTDAVLAQVEKMAETLLSNPVIENYTVSVEQ
>NZ_CP009896.1|WP_052139028.1|4738399_4739428_-|AraC-family-transcriptional-regulator
MDHDRASGEPDQNPTDALGSALDDLHVGGAIFLRAHYTEGWAFRSVPNDDLGALLAPEARRIVPFHLVDTGRCWIDVDGERYWAQAGDVIVLPYGDRHRMGGTEDAVVVEAGGLVPPPPWERMPFIEHGAGGALTHLVCGYITCDDPLFDPCLRALAPVVVVRPEGAAAQWVRASVDLALQRTGLVDAGHAQTPRDLVRMLLVEVLRLHLASVPAADRGFVRALRDPVVAPAVGAIHRSPEIGWTVRSLAAESHVSPSLLDERFRTVLGMPPIRYLTTWRMHVAQGLLATTGLGVAVVARRVGYESEEAFSRAFKRKHEVAPSRWRRRARGALDCGPWPESS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_14

4937656-4937748

Orphan

Consensus_repeat	Method
GGCTGGCCGTAGGGCTGCTGGGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_14

>merge|NZ_CP009896|14|4937656-4937748|CRISPRCasFinder
GGCTGGCCGTAGGGCTGCTGGGGCTGGCCGTAGGGCTGCTGCGGCTGCTGCGGCTGCTGCGGCGGCTGGGGCTGGCCGTAGGGCTGCTGCGGC

>NZ_CP009896|14|14|4937656-4937748|CRISPRCasFinder
GGCTGGCCGTAGGGCTGCTGGGGC	TGGCCGTAGGGCTGCTGCGGCTGCTGCGGCTGCTGCGGCGGCTGG
GGCTGGCCGTAGGGCTGCTGCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_052139062.1\|4935652_4936786_-\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|213783
NZ_CP009896.1\|WP_075018443.1\|4939923_4940946_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368383
NZ_CP009896.1\|WP_082004031.1\|4942854_4943289_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP009896.1\|WP_038682033.1\|4934678_4935656_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP009896.1\|WP_144405067.1\|4928500_4929973_+\|M1-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341066
NZ_CP009896.1\|WP_038682049.1\|4946499_4947561_-\|phenylacetaldoxime-dehydratase-family-protein	unknown	unknown	gnl\|CDD\|372736
NZ_CP009896.1\|WP_075018505.1\|4941635_4942340_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP009896.1\|WP_038682038.1\|4937853_4938756_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_052139060.1\|4925836_4928374_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366534
NZ_CP009896.1\|WP_052139065.1\|4940942_4941560_-\|DUF2510-domain-containing-protein	unknown	unknown	gnl\|CDD\|378480
NZ_CP009896.1\|WP_038685379.1\|4932175_4932529_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133388
NZ_CP009896.1\|WP_038682044.1\|4943355_4944210_+\|3-hydroxybutyryl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|181133
NZ_CP009896.1\|WP_038682029.1\|4932512_4933295_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378271
NZ_CP009896.1\|WP_038682046.1\|4944711_4946415_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341278
NZ_CP009896.1\|WP_052139063.1\|4938769_4939492_-\|DUF2510-domain-containing-protein	unknown	unknown	gnl\|CDD\|378480
NZ_CP009896.1\|WP_038682031.1\|4933297_4934665_-\|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl\|CDD\|237001
NZ_CP009896.1\|WP_038682023.1\|4922411_4925654_-\|(Fe-S)-binding-protein	unknown	unknown	gnl\|CDD\|223325
NZ_CP009896.1\|WP_038682027.1\|4931568_4932123_-\|serine-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|226075
NZ_CP009896.1\|WP_038682040.1\|4942370_4942763_+\|membrane-protein	unknown	unknown	gnl\|CDD\|224861
NZ_CP009896.1\|WP_038682025.1\|4930020_4931559_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_052139062.1\|4935652_4936786_-\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl\|CDD\|213783	TIGR03181, PDH_E1_alph_x, pyruvate dehydrogenase E1 component, alpha subunit. Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase].	5.3646e-170
NZ_CP009896.1\|WP_082004031.1\|4942854_4943289_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39667e-55
NZ_CP009896.1\|WP_038682033.1\|4934678_4935656_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	3.47553e-160
NZ_CP009896.1\|WP_144405067.1\|4928500_4929973_+\|M1-family-metallopeptidase	gnl\|CDD\|341066	cd09603, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain. This family contains mostly bacterial and some archaeal M1 peptidases with smilarity to the catalytic domain of aminopeptidase N (APN; CD13; alanyl aminopeptidase; EC 3.4.11.2), a type II integral membrane protease belonging to the M1 gluzincin family. APN preferentially cleaves neutral amino acids from the N-terminus of oligopeptides and, in higher eukaryotes, is present in a variety of human tissues and cell types (leukocyte, fibroblast, endothelial and epithelial cells). APN expression is dysregulated in inflammatory diseases such as chronic pain, rheumatoid arthritis, multiple sclerosis, systemic sclerosis, systemic lupus erythematosus, polymyositis/dermatomyosytis and pulmonary sarcoidosis, and is enhanced in tumor cells such as melanoma, renal, prostate, pancreas, colon, gastric and thyroid cancers. It is predominantly expressed on stem cells and on cells of the granulocytic and monocytic lineages at distinct stages of differentiation, thus considered a marker of differentiation. Thus, APN inhibition may lead to the development of anti-cancer and anti-inflammatory drugs. APNs are also present in many pathogenic bacteria and represent potential drug targets. Some APNs have been used commercially, such as one from Lactococcus lactis used in the food industry. APN also serves as a receptor for coronaviruses, although the virus receptor interaction site seems to be distinct from the enzymatic site and aminopeptidase activity is not necessary for viral infection. APNs have also been extensively studied as putative Cry toxin receptors. Cry1 proteins are pore-forming toxins that bind to the midgut epithelial cell membrane of susceptible insect larvae, causing extensive damage. Several different toxins, including Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ba, Cry1Ca and Cry1Fa, have been shown to bind to APNs; however, a direct role of APN in cytotoxicity has been yet to be firmly established.	3.00501e-128
NZ_CP009896.1\|WP_075018505.1\|4941635_4942340_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	6.7551e-32
NZ_CP009896.1\|WP_052139060.1\|4925836_4928374_-\|hypothetical-protein	gnl\|CDD\|366534	pfam01244, Peptidase_M19, Membrane dipeptidase (Peptidase family M19).	0.00164921
NZ_CP009896.1\|WP_052139065.1\|4940942_4941560_-\|DUF2510-domain-containing-protein	gnl\|CDD\|378480	pfam10708, DUF2510, Protein of unknown function (DUF2510). This is family of proteins conserved in Actinobacteria. Many members are annotated as putative membrane proteins but this could not be confirmed.	1.40082e-05
NZ_CP009896.1\|WP_038685379.1\|4932175_4932529_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133388	cd01282, HTH_MerR-like_sg3, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 3). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.68564e-34
NZ_CP009896.1\|WP_038682044.1\|4943355_4944210_+\|3-hydroxybutyryl-CoA-dehydrogenase	gnl\|CDD\|181133	PRK07819, PRK07819, 3-hydroxybutyryl-CoA dehydrogenase; Validated.	1.76016e-175
NZ_CP009896.1\|WP_038682029.1\|4932512_4933295_-\|hypothetical-protein	gnl\|CDD\|378271	pfam09844, DUF2071, Uncharacterized conserved protein (COG2071). This conserved protein (similar to YgjF), found in various prokaryotes, has no known function.	3.64346e-23
NZ_CP009896.1\|WP_038682049.1\|4946499_4947561_-\|phenylacetaldoxime-dehydratase-family-protein	gnl\|CDD\|372736	pfam13816, Dehydratase_hem, Haem-containing dehydratase. This family includes aldoxime dehydratase, EC:4.99.1.5. This is a haem-containing enzyme, which catalyzes the dehydration of aldoximes to their corresponding nitrile. It also includes phenylacetaldoxime dehydratase, EC:4.99.1.7. This haem-containing enzyme catalyzes the dehydration of Z-phenylacetaldoxime to phenylacetonitrile. The enzyme forms an elliptic beta barrel, composed of eight beta-strands, flanked by alpha-helices.	4.12007e-137
NZ_CP009896.1\|WP_075018443.1\|4939923_4940946_-\|hypothetical-protein	gnl\|CDD\|368383	pfam05308, Mito_fiss_reg, Mitochondrial fission regulator. In eukaryotes, this family of proteins induces mitochondrial fission.	3.87726e-06
NZ_CP009896.1\|WP_038682031.1\|4933297_4934665_-\|2-oxo-acid-dehydrogenase-subunit-E2	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	2.03143e-164
NZ_CP009896.1\|WP_038682023.1\|4922411_4925654_-\|(Fe-S)-binding-protein	gnl\|CDD\|223325	COG0247, GlpC, Fe-S oxidoreductase [Energy production and conversion].	6.52304e-84
NZ_CP009896.1\|WP_052139063.1\|4938769_4939492_-\|DUF2510-domain-containing-protein	gnl\|CDD\|378480	pfam10708, DUF2510, Protein of unknown function (DUF2510). This is family of proteins conserved in Actinobacteria. Many members are annotated as putative membrane proteins but this could not be confirmed.	3.59434e-08
NZ_CP009896.1\|WP_038682027.1\|4931568_4932123_-\|serine-hydrolase-family-protein	gnl\|CDD\|226075	COG3545, COG3545, Predicted esterase of the alpha/beta hydrolase fold [General function prediction only].	1.36125e-19
NZ_CP009896.1\|WP_038682040.1\|4942370_4942763_+\|membrane-protein	gnl\|CDD\|224861	COG1950, COG1950, Predicted membrane protein [Function unknown].	3.36916e-16
NZ_CP009896.1\|WP_038682046.1\|4944711_4946415_-\|AMP-binding-protein	gnl\|CDD\|341278	cd05974, MACS_like_1, Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS). MACS catalyzes the two-step activation of medium chain fatty acids (containing 4-12 carbons). The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. MACS enzymes are localized to mitochondria.	0

>NZ_CP009896.1|WP_052139062.1|4935652_4936786_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MTDPVFGPAPEQQADPELVQLLTPEGERVHHPGFDLDFTPDQLRGFFRDMTLVRRLDIEATALQRHGELGLWAQLLGQEAAQIGAGRALAPQDYVFPTYREHAVAWCRGVDPVKLLALFRGVDQGSWDPSEHNFGLYTIVIGAQTLHATGYAMGVQRDGLVGTGDPTRDTAVVAHFGDGASSQGDVNEAFVFAASYNAPVVFFCQNNQWAISEPFERQSRIPLYRRSQGFGFPGIRVDGNDVLATYAVMQAALQRAREGQGPILIEAYTYRMGAHTTTDDPTRYRLSDDVEHWKLKDPIARLEAYLRRNGLADDEFMTAVAAEADALGERMRRECHALPDPDLRDMFALVHAEQTAELAAQQAAYDEHAASFAEVTS
>NZ_CP009896.1|WP_038682033.1|4934678_4935656_-|alpha-ketoacid-dehydrogenase-subunit-beta
MTTMTLAKALNAGLRRAMEDDDKVVVMGEDVGTLGGVFRITDGLQKDFGDDRVIDTPLAESGIVGTAVGLAMRGYRPVVEIQFDGFVYPAYDQIVCQVAKLHFRSQGRIRIPMVIRIPFGGGIGAVEHHSESPEAQFAHTPGLKVVACSNPADAYAMIQQAVHADDPVIFLEPKRLYHSAKGEVDESAPPAPLWQSRVVRPGADATLVGYGPTVSTCLDAATVAAEEGRSLEVIDLRTLSPLDLLPVHESVRRTGRLVVVHEAHQTLGLGAEIAARVTEECFHSLEAPVLRVTGYDTPYPPARIEEAFLPDLDRVLDAVDRTFGF
>NZ_CP009896.1|WP_038682031.1|4933297_4934665_-|2-oxo-acid-dehydrogenase-subunit-E2
MANEFKLPDVGEGLTEAEIVAWRVKTGDVIAINDIVVEIETAKSIVELPSPYAGEVLALLVAEGDTVEVGTPIIRIGVPGAAPEPPTETPAAPPAETPVAPAVSTGGPVIIDTNVPPEGNATLVGYGPKQRALKRRTRKGEPAPAPAPAAAPVAEATVTRPVRALAKPLVRRLARDLGVDLTALVPTGPKGTVSKEDVLAATATPTATATATAAATPVAADPAGRETREPIKGVRKNMAAAMVSSAFTAPHVTEWVTIDATATVELVARLKERREFAGVKVSPLLVIARACLLALRRTPLLNSTWDEAAQEVVVKHYVNLGIAAATPRGLVVPNVKDAHALSLLELAQALETLTATAREGRTQPADLSGGSFTITNVGVFGVDGGTPIINPGESAILCLGAIKPQPWVVGDQVVPRQVMTLSLSFDHRHIDGATGSQFLADVAGLVGDPATALLF
>NZ_CP009896.1|WP_038682029.1|4932512_4933295_-|hypothetical-protein
MVDGVRGTERPPVRWFHAASDLADFMITTFRVAPERLARHLPPGWEPEVLPLAEGPAALVSAVAFRDEAFHFRGLPRVAITCGQVNYRAYVRRAGVLGAWFLGTAFDHATVALPRHLWGMPWHRERIALTAAWDDARATWRLRTDDAVCRATEAPVVPAGLDGFATDDAWHALLTHPTQGWYRRRRGGGVGTYSIWHPPMTVRHFVADDARFPFLERLGLVVPGQEPHSMLGQELLPFDIHTPPQRAVSGHRPARVTAGR
>NZ_CP009896.1|WP_038685379.1|4932175_4932529_+|MerR-family-transcriptional-regulator
MLIGELARRTGTTTRALRHYEDTGLLVPERTTAGYRTYAPADVARVAQIRALLDAGIGTATIRRFLGCARDGHHGTYLELCPDLRAELDAIAARMDAEQAALSARGARLAGLVTCPR
>NZ_CP009896.1|WP_038682027.1|4931568_4932123_-|serine-hydrolase-family-protein
MTTSATPPRATIIHGYGATPADHWFGWLAQRHAGAGLASAVPALPEPEAPDRERWLAATAAAVGTPAAGDLVVGHSLGCLTVLRHLAALPGDWRLGRLVLVAGFVDPLPALPGLDPYVAGAVPDLDRVAARTGAITVLRSDADAYVPAAHTDRLARLLGVPVRVVPGAGHFLADDGVTTLPDAL
>NZ_CP009896.1|WP_038682025.1|4930020_4931559_+|hypothetical-protein
MRLRSLAAAAAAGVLALTLGTAGSTSAAAGDDPALPGLPALPTIPGLPIPPLPTDLLVPRFTGAAVTPQPLDAPPVPQNPFLAPNGRSSMHNDAYSTDAYAVSGPTGRGLMMRTASYGIRECATVAFDSRDRIVGLCGGLEGFTLMVIDPVTLRAISQLQLSKRDLASGANPLTDICGGTYFFLDGDDRAFATTTDAAIAEVSVTAAGGLVKGRRWPLASYLPEDDCLVATGVDWSGRLWWFSQQGTVGTLDRATGAVRTLRLPAGEGIYNSVSTDETGGVYFVSTHQTYRLDAAADGTPGITWAIPYDRGTRKKPGMLSQGSGTSPTLIGEKWIVVADNAEPRSHVIVYDRRTGVPAGQREHCSIPVLADGASTTENSLVAAGNSVIIENNYGYAGVQSTLLGRSTTPGVSRVMIEDDGCHVAWTNPTVAPTSVPKASLGNGLVYVYSKPPGNLLDAWYVTAIDIRTGQTRWSRLTGTGIQWNNHYAAIYLGPDGSLYVATIVGLIRLADS
>NZ_CP009896.1|WP_144405067.1|4928500_4929973_+|M1-family-metallopeptidase
MTSSRPLGALGAALALCLTLAACGDDAVAGKAGATGVPTPTGEPTRITDRGDLSVARSETREDSVYPEPGDPVVDALHYALDLTWDPEQDRLTAEQRLTFRATADAPRIPLALSDALEVSALTVDGEKAEFTGDGDRLTIDHPVTADQQYVVELAYAGTPRPAEAPSTRSDFRQGLGWNITDDHETWTMQEPFGAFTWYAVNDQPADKALYDFTLTVPEPWSGVANGVLTDTTTRNGMVTDVWHLAEPASSYLVTVAFGHYQRTDLKSASGVPIQIWAPADGEPLPGGTGTAPDAIDWLEKILGPYPFESFGIVVVDNESGMETQTMVTLGNTEYSLSPAVVVHEAAHHWYGDTVSPADWSDVWMNEGMAMYLQGMWEAEQQSIPVAQKMDEWAGFEDDLRASAGPPGTYDPQQFGDGNIYYGPALMWQELREKIGDDEFFALLEDWPASRENRSTDRADYLGWIEKQTGEDLGAFFDAWLLGKQSPPRG
>NZ_CP009896.1|WP_052139060.1|4925836_4928374_-|hypothetical-protein
MAEDVTQEQGSGSRRVGLAALVALAVVGVALAVPTSGTGDGGLSLAAASEQAKSDRGIPHDDALLAPHDHNDPATKNDVSRGLAVGDEAVDPTTAGERRSAEKYVAAQRALPDPKLTHVRAYPARTVVPADRYAMAGGCYTLSSPVGSFGPYYFKATRLGGYLLHTPQGELTLQRTGAVSVAAKPSAQADWTVTRSARGFVLAIGAKALVAKARGVLGSGSSGTPFGLRAARGCPAYPEAGIDVTGDPFAGVTSYQEVRGFVDAHTHGMAFEFLGGKVHCGRPWHEYGAPYALDDCPDHKVTGGKGALLESVLSGKASHDPVGWPTFKDWPAPESLTHEGTYYRWLERAWRGGQRLFVNLLVENNKLCQLYPLKRNSCNDMDSIRLQAADMVKMQNYIDAQFGGPGKGFYRIVKDPFEARRVINGGKMAVVMGIETSIPFGCTYKKVLGRDQPACTSAEIDANLDAMHRLGVRQMELVNKFDNALAGVAGDAGAIGPLVNAANFLETGSFWAMEHCEPADGESADNAQITLPDITAGQQDALFGALGKVLGILPALPLYPQPAHCNKRGLTDLGVHTIKGLAKRKMVFDPDHLSVKARSASMDVIEGMRYPGVISSHSWSTPDTYPRIYRAGGFITPYAGDSTGFVAKWRRHLGWADSRYYFGFGFGADINGLGAQGNPRGTDVPNPVKYPFTGLGGVRIDKQRAGQRTWDINADGVAQYGLYPDWVEDLRKVADAQRRGDGAKIVDDMARGAEAYLQMWERTYGVRADSCRNPGLRMSKAKALRLAKRMVRTRMSTRDVMARVGQPYERLGTKFVFCAKSKQKAKVKVVVRFGAAGKVKAVRFR
>NZ_CP009896.1|WP_038682023.1|4922411_4925654_-|(Fe-S)-binding-protein
MQTLAIVVSLAVTVVAVALTVRAVRAMLGVIKRGQPAPGRTGNPVGRTLTMLKETFGHTRMLQWTWIGILHWFAFAAFIALSTAVAAAYIQLFDPEFTIPVIGKWWVYEWVAELLGLLGTIAIIPLIAYRLTHKPSQLGRRSRFFGSTMWQAYFVEAMVLLESSAILFIRGAEYNLAKAHGGEAAEHADGFHFPVSQFFANLFPTGHDSVGTLENIIFFIAMVKIVSAMVWLMVISTNLTMGVAWHRFTAWFNIWFKREETGRTALGAVKPLTSGGKPITLDDVDDLDEDAMLGAGSIWDFSWKDILDFTTCTECGRCQSQCPAWNTEKPLSPKLMMMAMREEAYAVAGGAEQRALVGKTEHDQADGVDDWFYMPEGGDFVVDEDALWACTNCGACVQQCPVDIEHVDHFVDMRRYQVLVESNFPSELNGLFKGLENKGNPWNMSPTARLDWAKDLPFEVKVVGDQIEDLESVDWLFWVGCAGAYEDRAKKTTRAVAELLDLAGVSFGVLGNGETCTGDSARRAGNEFVFQGLAQQNIETLTEAKAKKVVSTCPHCMNTLKNEYRDLGIELEVIHHTQLLNRLVREGKLTPVASGAGAHDRKITYHDPCFLGRHNQVYTPPRDLLQILPGAELAEMERNSERSFCCGAGGARMWMEETIGERINLNRTAEAVGTGADQVAVGCPFCRVMLSDGLTKMQADGEAREEVEVLDVAQMLLASVKGEQATKLLPGQGTPLAPKAAAPAAAGSGSVETKAEPEAGDVTITEDTVVETEDVGPAAKASGGSSMFDDPGSMFDTPAPAAPEPAAPAPAEPAEPAAKSGGSLFDDSGSLFDSPAPAPAAEAKPAEKPAEKPAEKADLGSGGSLFDLAEPEPEAKAKAEATPAPAPSADLGSGGSLFDIATPEPAPAAEPEPAPAAEPAPAAPAAAEPEPESAPAAASEPEPVTDVDLNAAGSLFDIAAPAAPAPAPEATPAAPAAAEPEPEPAPAPTPEAAPEPEPATDVDLNAMGSLFDIAAPAAPAPAATPAAPAAAEPEPATEPEPDPEPEPEAPKPAPPSPSSGAAHQPRTDADINEAGSLFDL
>NZ_CP009896.1|WP_038682038.1|4937853_4938756_-|hypothetical-protein
MRSFTAVVAILLATLLAPFAIGATWVSERVDDREAYVDTVGDLSDDPVVQQVLADAAADAAVKALERHIPVGLPSAVRGWARTAALKVVRSPDFPTFWRKANGDLHQQVLAVLDDPDAPTDGDITVDASPLVAQVLLQLEDRGIPVGLLPTIPLDVPVTTKAKVAEGGPAYRAADRFNRIVPLAWAALVLLGVLVAHGWRGRVRTAGFALLGVAVAAVVLLLAVDPATTAALDQVEADRRELTGVMLDAVVGSLTPYARAFLVAAPVGLVLVALSLWPRRTRAEQAPASAIPGADGHFTP
>NZ_CP009896.1|WP_052139063.1|4938769_4939492_-|DUF2510-domain-containing-protein
MPDPNQPSIPAGWYPDGLGGQRWWDGAEWTEHTQHTQHDQPPPPPPPPVPAPAPAVIARPDPNRSRTLLVLGAAGGGLLALLLVVLVAARVLGGNDPESVATDYLGATFEGDHEAVCELLVEERRDALLVDAGAGDDCGQYADEQRDREDEESDRYEDDYGVSVDDIRAGFDYDLEVTDVDERGDDEAIVEVEQTTDYSGDDDFAAEVLDGVDRQRTTVRLKIVKEDGDWKVADPFYTGD
>NZ_CP009896.1|WP_075018443.1|4939923_4940946_-|hypothetical-protein
MSDPNQPYGAPPPPPGPPGPPPPPLGPPPVGPPPVGPPPFPPPPPGPPGTGAGKGKGLWIALGVVGVLALVGVVVALVLVLTGGDDDGDDDTGSSDGPTSSARSPEDVVDDVLDAAEEGDCAAVEKLLTETARSARPCESDEFQLLAGDDVDSDVGTASIDGSTATVPVDFTSSQGSTEYLFTLEQVDGAWRVASYHAGRSTSSGTIVPSPPASSGTPSATGTPGATGTGTPSGTSTASAVPNEPAAVVEAFLDSAFAGDCATAEELVTEAYVKANGRCANDTIPTQLGDEVTYDVGQPTVDQARGTAKVPVKINAYGKSQDSVVSLVQEDGRWLIDRAG
>NZ_CP009896.1|WP_052139065.1|4940942_4941560_-|DUF2510-domain-containing-protein
MPGPTPSQPGWYPDADGNQRWYDGNAWTDHVRGDQQGAAQGDAQGGETVAVPPEPTAVLPTLPPPPPGTPGTPSSLEVGGGKGLRIAIAVLGVVLLLAIVVVGGIVLLGKDDGGKDEKVSEETSGTTDGDTPSDAPTSGLDLPTIDPSDFPTDLPSGLPSDLPSIPFPTKLPSEFPTDLLPSDFPTNPSELESWFSDFLEQVSPR
>NZ_CP009896.1|WP_075018505.1|4941635_4942340_+|GntR-family-transcriptional-regulator
MTAPSSSPRGRFATLSVEHASTVSRVAAELRRAVFEGELESGTPLREIALAESLGVSRPTVREALSVLVAEGLATREPHRGVAVATPRAESVRDVCRARWVLEGAGVQAWAGADDVRRQRVRDTLEAYTSAVRGGRASYEELNERHLSFHVSLVELTGSPRLVQMAEALMDELKLALAQVDRIRRNAHDEAESHEGLVTLLEAGRIDGPGGASEFLRQHIADAEVEVIDALGLE
>NZ_CP009896.1|WP_038682040.1|4942370_4942763_+|membrane-protein
MLAFLSRWAITAAALAVAAQLLDGIWFEGADAGRAELEDKILPLLLVALISCVVTAWVKPVLTFLSIPFILVTLGLFLVILNALLLRFTAWLAGLVDIGFHVSGFWAAFWGSIIISITTWFLDALVGVDD
>NZ_CP009896.1|WP_082004031.1|4942854_4943289_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MADVVLSARVADAGLDDVVEVVSAGTGGWHAGEPMDRRAAALLTAEGYDASRHRAQQVRASWLDTYDLVLAMDDANLADLQALGPADPARVRLFRDFDPEGTGEVPDPYYGGDAGFRDVLTLVERTADALTGDLLHVVLPTGHP
>NZ_CP009896.1|WP_038682044.1|4943355_4944210_+|3-hydroxybutyryl-CoA-dehydrogenase
MTGIERVGVVGGGLMGSGIAEVNARAGKDVIVVESSPAAVDNARQRLTSSLERAESRGKIESAAAVLDRIRVVDDLTALADRDIVIEAIVEDEAAKTDLFRRLDEIVTSPDAILASNTSSIPIMKLAVATQRPSHVLGVHFFNPVPVLKLVELVPSLMTDAATTERARAFVQDDLGKNAIDCQDRAGFVVNALLIPFILSAIRMLESGFATAEDIDQGLVLGAAHPQGPLALADLIGLDTTKAVAESLYEEFKEPLYAAPPLLARMVEAGLLGRKTGRGFYTYG
>NZ_CP009896.1|WP_038682046.1|4944711_4946415_-|AMP-binding-protein
MSTALGTARDLLRTHRTDRAAAVASFRWPDVGPSFNFVHDWFDGYARDNDQPALVIVEEDGARSSYTFGEMVTRSEQVAAYLAAQGVGRGDAVVVMLGNQVELWESMLALIRLGAVIMPTTTAVGTAELVDRLERGAARAVICNAADVPKFDEVPGAPVRVVVGSSDASGWLPYATAYESAAVPVPHPGNASDDRLLLYFTSGTTSRPKLVEHTHVSYPVGHLSTMYWLGLQAGDVHLNISSPGWAKHAWSNFFAPWLAEATVFVYNYARFDAAALLGQIRAEGVTTFCAPPTVWRMLINADLSGGPGVLREAIAAGEPLNPEVISQVEKHWGLTIRDGFGQTEMTACIANTPGQPVVPGAMGHPLPGMPVVLVDPLTGEVVPGVGEGELCLDLAAHPLPLMTGYQGDPAKNAEAMAGGFYHTGDVASRDADGCITYVGRTDDVFKASDYKISPFELESVLIEHPAVAEAAVVPAPDPVRLAVPKAYIALVPGHTPSAETAESILKYAREHLAPYLRVRRLEFFELPKTISGKIRRVELRHREVDAEASGQRSAGEFRDDDFPGLRG
>NZ_CP009896.1|WP_038682049.1|4946499_4947561_-|phenylacetaldoxime-dehydratase-family-protein
MESAIDTHLKCPRTLSRRVADDYAPPFPMFVGRGPKDLQQVVMASFGVQYADEDRRPQALAALRHIVGTFELADGPAHHDLTHHVDNQGHHNLMVLAYWADPAAYCRWLRSDEVAGWWASDERLTEGLGYFREIVAPRVEQLETLYAFTEDFPGVGTLMPQASGEIEEHGYWGSARDRMPISQTDWMEASGELTVVEGDPAQGGRVVVRGHDNICLIRSGQDWRAAGPDERDLYVDEILPTLQDGMDFLRDNGQDHGCYSNRFVRSIDLDGNELDESYNLGHWRSLDLLERWAESHPTHLRIFVTFFRVVTGLEKLRLYHEVSVSDGRDQTFEYINCHPATGMLRDARVPVAG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_15

4982395-4982482

Orphan

Consensus_repeat	Method
AGTTTCGCCGGTCGACCGGCGAAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_15

>merge|NZ_CP009896|15|4982395-4982482|CRISPRCasFinder
AGTTTCGCCGGTCGACCGGCGAAACTAACACCTGACCGACGAAGTTCCGTCGGTCAAGTAGGAGTTTCGCCGGTCAACCGGCGAAACT

>NZ_CP009896|15|15|4982395-4982482|CRISPRCasFinder
AGTTTCGCCGGTCGACCGGCGAAACT	AACACCTGACCGACGAAGTTCCGTCGGTCAAGTAGG
AGTTTCGCCGGTCAACCGGCGAAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038682101.1\|4986481_4987858_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038685394.1\|4980947_4982393_+\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|180854
NZ_CP009896.1\|WP_052139070.1\|4976813_4978409_-\|DUF853-family-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP009896.1\|WP_082004033.1\|4982555_4983677_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|235596
NZ_CP009896.1\|WP_038682100.1\|4985525_4986485_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_052139073.1\|4987847_4988219_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038682105.1\|4992409_4993126_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP009896.1\|WP_038682087.1\|4972500_4973775_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NZ_CP009896.1\|WP_038682085.1\|4972264_4972561_+\|EthD-family-reductase	unknown	unknown	gnl\|CDD\|131173
NZ_CP009896.1\|WP_052139072.1\|4985068_4985521_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038685393.1\|4979350_4980817_-\|potassium/proton-antiporter	unknown	unknown	gnl\|CDD\|235410
NZ_CP009896.1\|WP_038682094.1\|4975670_4976432_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238564
NZ_CP009896.1\|WP_038682091.1\|4974569_4975481_-\|glycoside-hydrolase-family-16-protein	unknown	unknown	gnl\|CDD\|185693
NZ_CP009896.1\|WP_038682102.1\|4988202_4989531_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|376607
NZ_CP009896.1\|WP_038682103.1\|4989689_4990676_+\|diiron-oxygenase	unknown	unknown	gnl\|CDD\|378680
NZ_CP009896.1\|WP_038682104.1\|4990697_4992389_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|215457
NZ_CP009896.1\|WP_052139071.1\|4978790_4979327_+\|LytR-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379163
NZ_CP009896.1\|WP_038682089.1\|4973932_4974430_+\|thioesterase-family-protein	unknown	unknown	gnl\|CDD\|372545
NZ_CP009896.1\|WP_038682096.1\|4978489_4978786_+\|type-II-toxin-antitoxin-system-VapB-family-antitoxin	unknown	unknown	gnl\|CDD\|227737
NZ_CP009896.1\|WP_038682099.1\|4983673_4984903_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038685394.1\|4980947_4982393_+\|FAD-binding-protein	gnl\|CDD\|180854	PRK07121, PRK07121, FAD-binding protein.	0
NZ_CP009896.1\|WP_052139070.1\|4976813_4978409_-\|DUF853-family-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP009896.1\|WP_082004033.1\|4982555_4983677_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	3.88495e-141
NZ_CP009896.1\|WP_038682102.1\|4988202_4989531_-\|acyltransferase-family-protein	gnl\|CDD\|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	2.93478e-12
NZ_CP009896.1\|WP_038682087.1\|4972500_4973775_-\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.50199e-13
NZ_CP009896.1\|WP_038682085.1\|4972264_4972561_+\|EthD-family-reductase	gnl\|CDD\|131173	TIGR02118, TIGR02118, conserved hypothetical protein. This model represents a small family of proteins of unknown function, each about 105 amino acids in length. Conserved sites in the multiple alignment include a pair of aromatic residues, a histidine, and an aspartate. [Hypothetical proteins, Conserved].	4.65517e-20
NZ_CP009896.1\|WP_038682105.1\|4992409_4993126_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.7929e-06
NZ_CP009896.1\|WP_038685393.1\|4979350_4980817_-\|potassium/proton-antiporter	gnl\|CDD\|235410	PRK05326, PRK05326, potassium/proton antiporter.	0
NZ_CP009896.1\|WP_038682094.1\|4975670_4976432_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238564	cd01144, BtuF, Cobalamin binding protein BtuF. These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).	1.47009e-48
NZ_CP009896.1\|WP_038682091.1\|4974569_4975481_-\|glycoside-hydrolase-family-16-protein	gnl\|CDD\|185693	cd08023, GH16_laminarinase_like, Laminarinase, member of the glycosyl hydrolase family 16. Laminarinase, also known as glucan endo-1,3-beta-D-glucosidase, is a glycosyl hydrolase family 16 member that hydrolyzes 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans such as laminarins, curdlans, paramylons, and pachymans, with very limited action on mixed-link (1,3-1,4-)-beta-D-glucans.	9.18322e-57
NZ_CP009896.1\|WP_038682103.1\|4989689_4990676_+\|diiron-oxygenase	gnl\|CDD\|378680	pfam11583, AurF, P-aminobenzoate N-oxygenase AurF. This family is a metalloenzyme which is involved in the biosynthesis of antibiotic aureothin by catalyzing the formation of p-nitrobenzoic acid from p-aminobenzoic acid. AurF is a non-heme di-iron monooxygenase which creates nitroarenes via the sequential oxidation of aminoarenes.	1.93656e-101
NZ_CP009896.1\|WP_038682104.1\|4990697_4992389_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|215457	PLN02852, PLN02852, ferredoxin-NADP+ reductase.	4.17106e-135
NZ_CP009896.1\|WP_052139071.1\|4978790_4979327_+\|LytR-C-terminal-domain-containing-protein	gnl\|CDD\|379163	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator. This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family.	1.67149e-12
NZ_CP009896.1\|WP_038682089.1\|4973932_4974430_+\|thioesterase-family-protein	gnl\|CDD\|372545	pfam13279, 4HBT_2, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	9.71058e-20
NZ_CP009896.1\|WP_038682096.1\|4978489_4978786_+\|type-II-toxin-antitoxin-system-VapB-family-antitoxin	gnl\|CDD\|227737	COG5450, COG5450, Transcription regulator of the Arc/MetJ class [Transcription].	2.38574e-08

>NZ_CP009896.1|WP_038685394.1|4980947_4982393_+|FAD-binding-protein
MAIPDTLPADVLTPDTEQYDVVVVGFGIAGGCAALEAARSGARVLLLEKAAVHGGTSSMSGGHFYLGGGTAVQQATGHDDSVEAMVGYLMASTKNPDEEKIRAYCEGSVAHFDWLEDLGFQFERSYFPGKAVIQPGTEGLMFTGNEKVWPFREQVAPAPRGHKVPVPGDTEGTRIVMDLLREQCEKEGVEVRYETGATNLVVDGDGGAVVGLAWRSFDRTGVIGARGVVIAAGGFVMNADMVARYTPALGSKLFTLGSTYDDGLGIRLGESVGAALEHMEEPFITAPFYPPSSRCKGIIVNKDGQRFVAEDSYHARTSYHVLQQPDAVAYLIVDSEHLGEDHMPLVPLKDGFETLEEMEAGLGMPAGALVATVTRYNENAARGEDPDLHKHPDWIAPQTAGPWAVLDLSLGVALYAGFTIGGMATTVDGEVRRPDGSVVPGLYAAGACASNIAQDGAGYCSGTQLGEGSFFGRRAGRHAAG
>NZ_CP009896.1|WP_038685393.1|4979350_4980817_-|potassium/proton-antiporter
MFLLIGAGVTFLAVLAVRASFGLGLPSLLVYLLMGVALGEAGLGIGFEDAQLAHALGFGALAVILAEGGLTTNWRDARPAMRLGLSLATLGVLVSIVVVAVGAHFLLGLSWQLSILLGAICSPTDAAAVFSVLRVVPLPKRITGTLEAESGLNDAPTVVLVTLVSSGAVGEHGLLGTTGIMVYELVAGVGIGLAAGFGGAWVMRRVALPASGLYPIAVLCLTFIGYGAAAEVHASGFAAVFVAGLVLGNADLPHRAATRSFVEGLAWLAQIGLFVMLGLLLSPERLSWATVGMAVVAGLLLTFLARPLSVLVSAVVRPMKLPELAFISWAGLRGAVPIVLATIPLAAGVDGATRLFDIVFVLVVIDTLITGPTLPLTARLLRVARRSEPRGIDVETAPLERVAADLLQITISPSSKLHGVEVGELRLPVGANVAMVVREGHTLVPERRTVLRHGDDLIVVTPRKLREDTERRLRQVSSGGRLAQWLHD
>NZ_CP009896.1|WP_052139071.1|4978790_4979327_+|LytR-C-terminal-domain-containing-protein
MVLDVRENSRTAITLAVLAVLFLGGVVWAWSQVAEPFPEKAEAAPCTDTLIPAGDDVAPPQVMVTVLNAGGPNGLAGQTLTKLESFGFVKGKLGNAPSSTGAVGAQVWASDPGDPAALLLASYLGKNVDIVDQPSGYPGITIVVGKRFQGVKKGQAKVTAQKDSHVCTPPLSRQPDAT
>NZ_CP009896.1|WP_038682096.1|4978489_4978786_+|type-II-toxin-antitoxin-system-VapB-family-antitoxin
MIFKRVGDGRPYPDHGLTSKGWAAVPPRQIRLDQLVTTKDTLQLSSLLDEDSTFFGDLFAHVVLWQDDYYLEDGLHRALRAALQQRHVLHARVIRMEG
>NZ_CP009896.1|WP_052139070.1|4976813_4978409_-|DUF853-family-protein
MTQEQTPTPDAAPETTNPIEQAIAPGYAFEGPALELGGLMAGPDELTGSTIRIPLAMLNRHGLVAGATGTGKTKTLQLLAEQLSAAGVPVFAADIKGDLSGLATAGEANDKLLARTKSVGQDWTATAFPVEYYALGGQGIGIPIRVTVTSFGPILLSRVLGLNDTQESSLGLVFHYADKQGLPLLDLSDLRAVVQHLTSDEGKADLKDLGGLSAATAGVILRELIAFADQGAEAFFGEPEFDSADLLQQAADGRGLINLVELPNLQDRPAIFSTFLMWLLADLFHDLPEVGDVDQPKLVFFFDEAHLLFKDASKPFLESIAQTVRLIRSKGVGVFFVTQSPTDVPDDVLAQLGSRIQHQLRAHTPNDAKALKATVNTYPKSAYADLGEVITTLGIGEAIVTVMGEKGAPTPVAWTRLRAPESLMAPSSTESMEATVKASPRAATYSEVVDRESAREMLAKRLEEGAKAAKEAKETEEAKPKGSAPTKKKDDGGGAGEIVKDVVKSSAFKQFMRTAAAEIARGMFGTARRRR
>NZ_CP009896.1|WP_038682094.1|4975670_4976432_+|ABC-transporter-substrate-binding-protein
MSGTSASPVDDLGAPVPLSAPARRVVSLVPSITEALAADVPDRLVGATDWCTHPADLDVRRVRGTKNPDLAAIRALAPDLVVANKEENRELDVRRLREAGVAVWVTDIETVPQALTSLERLYDEALAHARPDWLRQARERWDRPVPPSRGRVAVPVWRDPWMVVGPRTYTGDLLRRLGWTNAFDDSADRYPHVELAALDRDDDVDLVLLPDEPYVFTSDDGPEAFTRVPTRLVSGRLLTWYGPAMVEAYDELS
>NZ_CP009896.1|WP_038682091.1|4974569_4975481_-|glycoside-hydrolase-family-16-protein
MLRLRLLCVVGTAVVATAALAPVVSTSASGIPVAAAAAAPASGPTCGGERPAKESGGRYTCSFDDDFNGTSLDATKWVVQETAVTGISALGKGCYVNSPNNVRVSGGQLQLTSRKESAYFQCTSPFGTYTTERTAATIGSYGLFNQTFGRFEFRAKMPATTVSGIHSALWLYPQKHTYGGWPNSGEVDVAEWFSADAGRVYPSVHYAGEDTRLSTGYNCRVPQSSQYHRYAVEWTPTSMRFLYDNRVCFTHRWTPASPLVAPQPFDQPFYVVLTQVFGGAWNSITAQTPTSATMTVDWVRVWK
>NZ_CP009896.1|WP_038682089.1|4973932_4974430_+|thioesterase-family-protein
MSTQPTYDQLASLPAFAVQPVPSAFEDSNGFLNVRHYLGIGSEGLDESLYDLGIPFNWPVLTGFACLSAEHHLTYLHELRTGDQMSVRVRLLGRAERAAHAQVYVLDDTNQRVACVFEEIFLCVRLDDRKTAPWPDDIAKGLDQRVADHAALPWEPVTSGSLALR
>NZ_CP009896.1|WP_038682087.1|4972500_4973775_-|MFS-transporter
MPAHAPSLVRATGASYFPIALVARLPYAMMVVGVLTLVVAGRDSLAFGGLNSAVVGLGAACVGPLLGAAADRFGQRRVLLASGVASATALALMAWVVYSPLPGAAVLAVAFLVGASAPQIAPMSRSRLVQIIGSKIAPGRRSRTFDATMAYESAADEIVFIIGPFVVGLLGTTLDPWAPVAGAAVLTLVFVSAFALHPSAAVAERHGEQALPAAPARELTRPALLAVVAGIFGVGLFFGAMLTSLTSFMGDHGSAASAGLVYGVMGIGSATLALSVALFPKAFSLRARWLVFGATMLAGALLLPLASSVLQMCLVLLVIGCGIGPTMVTQYSLGAHRSPAGRSATVMTILGSAVIVGQSAASAVTGNLADRFGTDAALVMPIVAAAVVVLAGAANWVLSPAPAGGQSPSTTMVTPPLANAGTSA
>NZ_CP009896.1|WP_038682085.1|4972264_4972561_+|EthD-family-reductase
MPTLTVLYGPPVDPAAFRRHYEEVHLPLARELPGASDLSVTLDVDTLAGEHPVFAVFRARFATRSALDAALASPAGQAAQADVPAFASGGVTIVVEGD
>NZ_CP009896.1|WP_082004033.1|4982555_4983677_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MDLLAAAAERQRTHGDLVNLVAGQPSSGAPAPVTAAAVRLLGSGDPLGYTTATGVVELRTAIAGHYRRAYGIAVDADDVIVTTGSSGGFLLAFLAAFDAGARVAIARPGYPCYRNVLSALGCDLVEIPTGPATRFQPTVEQLAEAHARTPLDGLVVASPANPTGTMLLPEELAALARWCDENGVQLVSDEIYHGIQYAGARSSCAWETSREAIVFGSFSKYFSMTGWRLGWMLAPERLRRPVDVLTGNFSICPPALAQHAALAAFDDASYAELDGHVARYAHNRGLLLDGLRRLGIERLAPADGAFYAYADVGHLTTDSMAYCRDLLARTGVAVATGVDFDIVDGGRFLRFSFAGTADDITTALDRLDGRLLP
>NZ_CP009896.1|WP_038682099.1|4983673_4984903_-|hypothetical-protein
MRGRSRAAFAPEDVADARRGEPATDLSGWAAEAGWEYLGQRVPSGFVSVVPVWAEHLFSCARGVLPGDVFGTVLHELYEVGVDGDGLAMDGEFHDLRSDGTWKWLGSWDNGPRNEPFARNAVWLPATRGAARVPQAALLPRLCVRRADRLPPHGSRDLGDLGLDGFRLTGETDPVLDEIVATWLGGEAGAALRALPHPFVEVVVAGGHLALVRNGYVAPGEADAFVTALGALARGLRAACAPLAVPAPVGSELPPPAWADAVHAAPGLLDVLSGAWWSAYRDLAAERGLTLEDPDAFHRAFPDQPVPGRAQGVLRGRVDGLPGDVRLAWFADAEAPVDGWVRAALLLPAPDVGARTRRGGTLVEETGMWGEVVGDIAACWTVRRLPGTLDADGVVPAAVATARRLGFVP
>NZ_CP009896.1|WP_052139072.1|4985068_4985521_+|hypothetical-protein
MYGDSEIIRRRVSQLRDQGADVRALADELVARVEALGWTGRAGDAMRERVTDRASHLRIAADRHTGAADALADHAEAVDAVRDEIGATQTRVSALVADARGRIAAIARRNEAGDGPAITPDPLDETLAAFTPPPPGHRDWLDVDVPGLER
>NZ_CP009896.1|WP_038682100.1|4985525_4986485_+|hypothetical-protein
MPTIDLTTVGTVGATPAPAPTGTGTALVAAPRRIGLTLAELQHAAHLAGGAPLPFELAPPRDTDAMQARLGRSPATLDDQAYRSVVAALHDPAESLGRRGLVDPTGTRLDPGLAGAIGLLAAPRLALDVDVAMAGVQAKVWHRQDGAAVASLATADGLVFEVGWFGTDAWPAELARIAVLSEEVDLGRSAVPAYVDLPFELADAAAEAGSAGRGDLLPVLAARHTGRVHGADGPLADDVVVRILTALSGEARGRLRALVADVSGDAVDTVGVVSWSLLADGWRALRPHHADGVLRLEVRSVVPDDLAAVVAPVLGEAAR
>NZ_CP009896.1|WP_038682101.1|4986481_4987858_+|hypothetical-protein
MTREQQAPPAAAPAPAPAPTAVEVADLADKYDQMLRLADLFDDAGAQMRSWAQLGRDVLGDPDVAESAPLSPATWAIADEEVRAATTGKGGLLGRSIELDADALVLRATVLTYRWIDELQAAAYQTLGSIAGKAIGYLAPEVNLGGAIVAAGLIETDALDRDGVAAYLGELAEANPELMEHVTTGGGVLDSLQMRGLLTAGVHSGESGAAARAGGLRAAGITPLTDDWAAALRDVAVDLTEGADATTATAPGTITVGDPDAVPTGLGDLMALLVGGSDHEPVRVLRVGPGRLVVLVSGGGTPEPAPGRLRLVSGDASGQAGAVIRTLGAAVEPGPEPTRVMLVGRGSGGAAALEVATRTDLPGFVVDQVVTANAPAAQLPALPADVQVLSLEDRSDPVALLGSLINAGTPNRVTVVYDAGSEPGVPALVAGGRAADRADHPDLRAALERWRAAGYLRG
>NZ_CP009896.1|WP_052139073.1|4987847_4988219_-|hypothetical-protein
MERSSDADGLAWVVVQYPTQTKRRDDWLIDHASEWLGSVLAERGLGHVDGHDRGKRISDGALVVNIFARVSDAEAGCTAAMSALRQGRADERRATIAHRADDGDTWTVRYARTSGRLPGEFSL
>NZ_CP009896.1|WP_038682102.1|4988202_4989531_-|acyltransferase-family-protein
MSHALLPSAAALADRTPPERNRVVDLLRAAAILVVVLGHWLMAAVYVDRDGGLHRGDLLDLAGWTHPLTWVLQVMPVFFLVGGYANALSWRSARRRAQPYGGWLRSRLRRLVLPVLPLMVFWAVLAPSAHALGADPDLLRIASRASLVPTWFLAAYVVVVALAPLTLAVWERAGWWAVGGGLALAGLVDYVSVSRDLLAVGFLNYVLVWSTVHMLGYAWLDGRLASAGRRLALVALGLGVLWLLTVHGPYAVSMVGVRTDEIDNAYPTRVTQGFLGLLQAGVVLTLEPLLQRLVARRRVWVATVLVNARIMSIYLWHLTMLGALVAGSLALDGLGLHRLPDTGGWWATRPLYFAVLALLTAGAVAVVGRFETPAADPRPAPAPWRPVLAVLGVCGGLGALAALGITRDGVVLWWLPLVPLAACLAGGVVRLPGSLDRRGAEQ
>NZ_CP009896.1|WP_038682103.1|4989689_4990676_+|diiron-oxygenase
MTATADTPVDTTDLSYQDTLRVLSEASVHQHFDAFLDIAWDSPELAVVPDDPRWILPEVDSLGGTDWYRSLPQERQIEVGMYRMANIAKVGLQFEQLLIGGVMNHLMTMPNNRAEFRYSTHEVTEECHHTQMFQEAVNRIGIDVQGGPTWFLKIAPFLALAGRPMPNIFFFGILAGEEPIDYLQKSVLRSGHDMHPIITRVMQIHVAEEARHIGFAHSYLVERSKDYGTLQRFGLSLAFPVIMRLLCDVIMKPSKQMQKDLGIPKSVMREVYWKSEKSEKLLRDTFGDVRMLADELGLMNRVSRRVWRMLGIDGRPSRFRSEPKSAAV
>NZ_CP009896.1|WP_038682104.1|4990697_4992389_+|FAD-dependent-oxidoreductase
MAYVVTQSCCADASCVVACPVNCIHPAPGEPGFGTTEMVYVDASSCVGCGACATACPVGAMVPDAALTTKQLPFLDLNASYYDAFPHADRTPVALVPQQRRLTRTGPFRVAVVGAGPAGLYTADELLKHPEVGGVDVYDRLRTPYGLVRHGVAPDHASTKLVTRLFEAIERQPRFRYFLDVPVGAPEHPGGVTLADLRAHYDAVVYAVGASADRSLGIPGEELAGSVAATALVGWYNGHPDQQALDVPLAHERAVVVGNGNVALDVARILARPIDVLERTDLAPGPLDRLRASAVREVLVLGRRGPAQAAFTVPELIGLAALDDVDVLVEADPALLTGDDQRSALLRELAERPVDLASTRRRIVLAFASSPVEVLGADGRVSGVRVARNELVTDADGTVRAVPTDDVRTIEAGLVVRSVGHRGTPVAGLPFDERTATVPNHQGRVEPGLYVVGWIKRGPVGFIGTNKTDAQETVETILDDLDAGLPAPTGSAAAIAALVAERHPQSADLAAWQRLDAAERERGAQAGRPRAKITDVAEQRSVAAAPVATRRRGLLRRTVSLTS
>NZ_CP009896.1|WP_038682105.1|4992409_4993126_+|TetR/AcrR-family-transcriptional-regulator
MAAPSGRRDQTDGRKRRWQQHNADRRQAVIDAALTVLARDLEPGAELSVQLIADEASVHRTVLYRYFDDRTDLDVAIQQEICTRAGELLLAAVTLEGTPREIVERIVHAYVDWGAANVALMRFAERDIPGAATKPLDLAIGQIAEQIELVIGGFLAVLEADVEEDDRDALTPWVFLLVGGVMAAVRNWSSREELRPPAPQFTRLLADVTWLQIEGLAASRNIEVPDLPVEQLLNLKEA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_16

4994591-4994681

Orphan

Consensus_repeat	Method
CGGCAGTTTCACCGCCTAGGCGGTGAAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_16

>merge|NZ_CP009896|16|4994591-4994681|CRISPRCasFinder
CGGCAGTTTCACCGCCTAGGCGGTGAAACCGGACCTGGGCACAGGGAGTTCCGTGGGCCAACCGGCAGTTTCACCGCCTAGGCGGTGAAAC

>NZ_CP009896|16|16|4994591-4994681|CRISPRCasFinder
CGGCAGTTTCACCGCCTAGGCGGTGAAAC	CGGACCTGGGCACAGGGAGTTCCGTGGGCCAAC
CGGCAGTTTCACCGCCTAGGCGGTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_082003815.1\|4998960_4999833_-\|NERD-domain-containing-protein	unknown	unknown	gnl\|CDD\|377990
NZ_CP009896.1\|WP_038682107.1\|4994688_4996098_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|283431
NZ_CP009896.1\|WP_038682105.1\|4992409_4993126_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP009896.1\|WP_038682100.1\|4985525_4986485_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_052139073.1\|4987847_4988219_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038682108.1\|4996100_4997018_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP009896.1\|WP_038682114.1\|5003855_5004473_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP009896.1\|WP_052139074.1\|5001425_5002937_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP009896.1\|WP_052139072.1\|4985068_4985521_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_038682106.1\|4993126_4994584_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224983
NZ_CP009896.1\|WP_038682101.1\|4986481_4987858_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_162484134.1\|5000273_5001380_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|224561
NZ_CP009896.1\|WP_082003817.1\|5003047_5003836_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|172294
NZ_CP009896.1\|WP_038682103.1\|4989689_4990676_+\|diiron-oxygenase	unknown	unknown	gnl\|CDD\|378680
NZ_CP009896.1\|WP_038682104.1\|4990697_4992389_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|215457
NZ_CP009896.1\|WP_038682102.1\|4988202_4989531_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|376607
NZ_CP009896.1\|WP_038682110.1\|4997134_4997530_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_082003816.1\|4999906_5000269_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378915
NZ_CP009896.1\|WP_141267412.1\|4997591_4998950_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP009896.1\|WP_038682099.1\|4983673_4984903_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_038682105.1\|4992409_4993126_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.7929e-06
NZ_CP009896.1\|WP_038682108.1\|4996100_4997018_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.78013e-40
NZ_CP009896.1\|WP_038682114.1\|5003855_5004473_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.9827e-13
NZ_CP009896.1\|WP_082003816.1\|4999906_5000269_-\|hypothetical-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.00581927
NZ_CP009896.1\|WP_038682107.1\|4994688_4996098_-\|VWA-domain-containing-protein	gnl\|CDD\|283431	pfam05762, VWA_CoxE, VWA domain containing CoxE-like protein. This family is annotated by SMART as containing a VWA (von Willebrand factor type A) domain. The exact function of this family is unknown. It is found as part of a CO oxidising (Cox) system operon is several bacteria.	9.30319e-30
NZ_CP009896.1\|WP_082003817.1\|5003047_5003836_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|172294	PRK13756, PRK13756, TetR family transcriptional regulator.	4.77274e-10
NZ_CP009896.1\|WP_038682106.1\|4993126_4994584_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.06706e-123
NZ_CP009896.1\|WP_082003815.1\|4998960_4999833_-\|NERD-domain-containing-protein	gnl\|CDD\|377990	pfam08378, NERD, Nuclease-related domain. The nuclease-related domain (NERD) is found in a range of bacterial as well as archaeal and plant proteins. It has distant similarity to endonucleases (hence its name) and its predicted secondary structure is helix - sheet - sheet - sheet - sheet - weak sheet/long loop - helix - sheet - sheet. The majority of NERD-containing proteins are single-domain, but in several cases proteins containing NERD have additional domains which in 75% of cases are involved in DNA processing.	3.11792e-13
NZ_CP009896.1\|WP_038682104.1\|4990697_4992389_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|215457	PLN02852, PLN02852, ferredoxin-NADP+ reductase.	4.17106e-135
NZ_CP009896.1\|WP_038682102.1\|4988202_4989531_-\|acyltransferase-family-protein	gnl\|CDD\|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	2.93478e-12
NZ_CP009896.1\|WP_052139074.1\|5001425_5002937_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.13059e-48
NZ_CP009896.1\|WP_162484134.1\|5000273_5001380_-\|alpha/beta-hydrolase	gnl\|CDD\|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	0.000240547
NZ_CP009896.1\|WP_141267412.1\|4997591_4998950_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.84454e-09
NZ_CP009896.1\|WP_038682103.1\|4989689_4990676_+\|diiron-oxygenase	gnl\|CDD\|378680	pfam11583, AurF, P-aminobenzoate N-oxygenase AurF. This family is a metalloenzyme which is involved in the biosynthesis of antibiotic aureothin by catalyzing the formation of p-nitrobenzoic acid from p-aminobenzoic acid. AurF is a non-heme di-iron monooxygenase which creates nitroarenes via the sequential oxidation of aminoarenes.	1.93656e-101

>NZ_CP009896.1|WP_038682106.1|4993126_4994584_+|NAD(P)/FAD-dependent-oxidoreductase
MSDSVEHLDVLIVGAGLSGIDAAYHVGKAFPTRSYAILEMRDALGGTWDLFRYPGIRSDSDMYTLGFGWKPWKGKKAIADGADIRAYLQEAARENGIDQHIRYHHKLVHADFSTEDARWTVTVERTDTGETKQITASFLWSTSGYYRYDEGFTPDFAGLADFQGQVVHPQHWPEDLDYQGKKVVVIGSGATAVTLIPSLAESGAGHVTMLQRTPTFIVSQPLTDPISYRLLQTLPDKIAGKLVRGRYLAMTIGFYEFCRARPREARALIRKMSERQLPKDVSYDEHFTPPYAPWDQRLCVVPRGDLFKALRKHTVDMVTDRIARFTERGILLESGRELEADIVVTATGLNLQVFGGATLAVDGADIKLPDTMAFKGMMLSDIPNFAFIVGYTNASWTLKADLVCQYVVRVLQHMEKTGKRVVVPRRDPAVAEEPFLDFEAGYVMRSITQFPKQGSVEPWRLKMNYFKDLRVFGKAPTDPALEYTA
>NZ_CP009896.1|WP_038682105.1|4992409_4993126_+|TetR/AcrR-family-transcriptional-regulator
MAAPSGRRDQTDGRKRRWQQHNADRRQAVIDAALTVLARDLEPGAELSVQLIADEASVHRTVLYRYFDDRTDLDVAIQQEICTRAGELLLAAVTLEGTPREIVERIVHAYVDWGAANVALMRFAERDIPGAATKPLDLAIGQIAEQIELVIGGFLAVLEADVEEDDRDALTPWVFLLVGGVMAAVRNWSSREELRPPAPQFTRLLADVTWLQIEGLAASRNIEVPDLPVEQLLNLKEA
>NZ_CP009896.1|WP_038682104.1|4990697_4992389_+|FAD-dependent-oxidoreductase
MAYVVTQSCCADASCVVACPVNCIHPAPGEPGFGTTEMVYVDASSCVGCGACATACPVGAMVPDAALTTKQLPFLDLNASYYDAFPHADRTPVALVPQQRRLTRTGPFRVAVVGAGPAGLYTADELLKHPEVGGVDVYDRLRTPYGLVRHGVAPDHASTKLVTRLFEAIERQPRFRYFLDVPVGAPEHPGGVTLADLRAHYDAVVYAVGASADRSLGIPGEELAGSVAATALVGWYNGHPDQQALDVPLAHERAVVVGNGNVALDVARILARPIDVLERTDLAPGPLDRLRASAVREVLVLGRRGPAQAAFTVPELIGLAALDDVDVLVEADPALLTGDDQRSALLRELAERPVDLASTRRRIVLAFASSPVEVLGADGRVSGVRVARNELVTDADGTVRAVPTDDVRTIEAGLVVRSVGHRGTPVAGLPFDERTATVPNHQGRVEPGLYVVGWIKRGPVGFIGTNKTDAQETVETILDDLDAGLPAPTGSAAAIAALVAERHPQSADLAAWQRLDAAERERGAQAGRPRAKITDVAEQRSVAAAPVATRRRGLLRRTVSLTS
>NZ_CP009896.1|WP_038682103.1|4989689_4990676_+|diiron-oxygenase
MTATADTPVDTTDLSYQDTLRVLSEASVHQHFDAFLDIAWDSPELAVVPDDPRWILPEVDSLGGTDWYRSLPQERQIEVGMYRMANIAKVGLQFEQLLIGGVMNHLMTMPNNRAEFRYSTHEVTEECHHTQMFQEAVNRIGIDVQGGPTWFLKIAPFLALAGRPMPNIFFFGILAGEEPIDYLQKSVLRSGHDMHPIITRVMQIHVAEEARHIGFAHSYLVERSKDYGTLQRFGLSLAFPVIMRLLCDVIMKPSKQMQKDLGIPKSVMREVYWKSEKSEKLLRDTFGDVRMLADELGLMNRVSRRVWRMLGIDGRPSRFRSEPKSAAV
>NZ_CP009896.1|WP_038682102.1|4988202_4989531_-|acyltransferase-family-protein
MSHALLPSAAALADRTPPERNRVVDLLRAAAILVVVLGHWLMAAVYVDRDGGLHRGDLLDLAGWTHPLTWVLQVMPVFFLVGGYANALSWRSARRRAQPYGGWLRSRLRRLVLPVLPLMVFWAVLAPSAHALGADPDLLRIASRASLVPTWFLAAYVVVVALAPLTLAVWERAGWWAVGGGLALAGLVDYVSVSRDLLAVGFLNYVLVWSTVHMLGYAWLDGRLASAGRRLALVALGLGVLWLLTVHGPYAVSMVGVRTDEIDNAYPTRVTQGFLGLLQAGVVLTLEPLLQRLVARRRVWVATVLVNARIMSIYLWHLTMLGALVAGSLALDGLGLHRLPDTGGWWATRPLYFAVLALLTAGAVAVVGRFETPAADPRPAPAPWRPVLAVLGVCGGLGALAALGITRDGVVLWWLPLVPLAACLAGGVVRLPGSLDRRGAEQ
>NZ_CP009896.1|WP_052139073.1|4987847_4988219_-|hypothetical-protein
MERSSDADGLAWVVVQYPTQTKRRDDWLIDHASEWLGSVLAERGLGHVDGHDRGKRISDGALVVNIFARVSDAEAGCTAAMSALRQGRADERRATIAHRADDGDTWTVRYARTSGRLPGEFSL
>NZ_CP009896.1|WP_038682101.1|4986481_4987858_+|hypothetical-protein
MTREQQAPPAAAPAPAPAPTAVEVADLADKYDQMLRLADLFDDAGAQMRSWAQLGRDVLGDPDVAESAPLSPATWAIADEEVRAATTGKGGLLGRSIELDADALVLRATVLTYRWIDELQAAAYQTLGSIAGKAIGYLAPEVNLGGAIVAAGLIETDALDRDGVAAYLGELAEANPELMEHVTTGGGVLDSLQMRGLLTAGVHSGESGAAARAGGLRAAGITPLTDDWAAALRDVAVDLTEGADATTATAPGTITVGDPDAVPTGLGDLMALLVGGSDHEPVRVLRVGPGRLVVLVSGGGTPEPAPGRLRLVSGDASGQAGAVIRTLGAAVEPGPEPTRVMLVGRGSGGAAALEVATRTDLPGFVVDQVVTANAPAAQLPALPADVQVLSLEDRSDPVALLGSLINAGTPNRVTVVYDAGSEPGVPALVAGGRAADRADHPDLRAALERWRAAGYLRG
>NZ_CP009896.1|WP_038682100.1|4985525_4986485_+|hypothetical-protein
MPTIDLTTVGTVGATPAPAPTGTGTALVAAPRRIGLTLAELQHAAHLAGGAPLPFELAPPRDTDAMQARLGRSPATLDDQAYRSVVAALHDPAESLGRRGLVDPTGTRLDPGLAGAIGLLAAPRLALDVDVAMAGVQAKVWHRQDGAAVASLATADGLVFEVGWFGTDAWPAELARIAVLSEEVDLGRSAVPAYVDLPFELADAAAEAGSAGRGDLLPVLAARHTGRVHGADGPLADDVVVRILTALSGEARGRLRALVADVSGDAVDTVGVVSWSLLADGWRALRPHHADGVLRLEVRSVVPDDLAAVVAPVLGEAAR
>NZ_CP009896.1|WP_052139072.1|4985068_4985521_+|hypothetical-protein
MYGDSEIIRRRVSQLRDQGADVRALADELVARVEALGWTGRAGDAMRERVTDRASHLRIAADRHTGAADALADHAEAVDAVRDEIGATQTRVSALVADARGRIAAIARRNEAGDGPAITPDPLDETLAAFTPPPPGHRDWLDVDVPGLER
>NZ_CP009896.1|WP_038682099.1|4983673_4984903_-|hypothetical-protein
MRGRSRAAFAPEDVADARRGEPATDLSGWAAEAGWEYLGQRVPSGFVSVVPVWAEHLFSCARGVLPGDVFGTVLHELYEVGVDGDGLAMDGEFHDLRSDGTWKWLGSWDNGPRNEPFARNAVWLPATRGAARVPQAALLPRLCVRRADRLPPHGSRDLGDLGLDGFRLTGETDPVLDEIVATWLGGEAGAALRALPHPFVEVVVAGGHLALVRNGYVAPGEADAFVTALGALARGLRAACAPLAVPAPVGSELPPPAWADAVHAAPGLLDVLSGAWWSAYRDLAAERGLTLEDPDAFHRAFPDQPVPGRAQGVLRGRVDGLPGDVRLAWFADAEAPVDGWVRAALLLPAPDVGARTRRGGTLVEETGMWGEVVGDIAACWTVRRLPGTLDADGVVPAAVATARRLGFVP
>NZ_CP009896.1|WP_038682107.1|4994688_4996098_-|VWA-domain-containing-protein
MTGPDAHSGLLDRHLAFVEALRGAGLSVSLAEDLDAVAALAAVHWSDRATVRDAFAATLVKKQTQRTTFDALFDVYFPAMVGDGAAGAEAPDDGAPGQVKDNAAALADFRERLAEALAAGEIDEAQLRQMAAEMVGVFGSMPGRGPGLSSWSAYTALQRVAPHELVDRLVQGLLDAGTDDDAARRQANRRIGEFTGLVEDDARRRIAEEKGPDHIADVAVRPSIDKLAFMAARRTDLDEMRKEIFPLARRLATRLAKEQHSRHARTAPLDFRRTVRASIATGGVPITTHHRPKRPHRTDLVVLCDVSGSVANFAQFTLLFVFALREVFQSMRAFTFIDHVHEVTGHFRPGADPVDVLADLAASASHAALWGRTNYGRAFTKFAENHADALTPKTTLLILGDARSNYSDLHEDTLKQLAGSVKRTFWLNPEHQRNWGTGDSAAPTYAEIVRMIECRNLTQLSEFVHELAW
>NZ_CP009896.1|WP_038682108.1|4996100_4997018_-|MoxR-family-ATPase
MSMTWFDSPTDATARLGAAGYLADAATATTTFLAGALEKPLLLEGPAGVGKTELAKAVSRATGAELVRLQCYEGLDEARALYEWNYKKQLLAIQASGAEAQAGPGSTGDGDHQSRPWEDLDRSIFTEEFLLTRPLLTAIRRDEPTVLLIDEVDKTDIEVEGLLLEVLSDFQVTIPELGTVAATRRPYVVLTSNASRELSEAVKRRCLYLHIDYPDAARERQILQQQVPGLDDRIAEQLVATVGRLRELELKKAPSIAESVDWARTLIALEIRELDEKAIKDTLGAVLKHQSDHERAVKELKLARS
>NZ_CP009896.1|WP_038682110.1|4997134_4997530_+|hypothetical-protein
MRDTITPPRWLQVGIHSVRTATTVAALTLLVGFGAVGVVATPQPSAPSTQLGLSMGPLDALMEHNRCSVTGFDRDVIPSTAIVRTPGGATELVSFDRGWAVFSGEAAGELVAVCLGPQAGAAPDGGRPNLR
>NZ_CP009896.1|WP_141267412.1|4997591_4998950_+|helix-turn-helix-domain-containing-protein
MDTHLAELSRTIDAAELGRRMRIARVAAGMTQAQVAGDDVSAAYLSRIEDGQRRPEAGLLERMANRMGVTLEDLLLDVPRDKVHELRLAVDHARLSLISGDPAAALAAVGLVLDDPATERIDFVQRAARQVRAGALEASGDLDGAILILEDLTSAPTPDAGWLRSLVALCRCYRDSGDHTRAISIAERSATLIDELGLSGLSEAVELTVTVAGAYELQGDTGQAMRMCARTLEAAEQHASAVDKATAYWTASRAEAERGGTQAALELADKALALFALGDDNRNLATLRAQVANLQLLADPADPAAALATLADAEPELSWSGASATEVALVHLTRGKAHFALGAHDAARECVEKATAAAPDDASVLRASISVLRGRIAFADGDRDGARALFRDGVTALTAAGSDRRAAQLWFELAELLTEVGDTEGAVQAFRSAGASTGLRVPSRTSAAVPQR
>NZ_CP009896.1|WP_082003815.1|4998960_4999833_-|NERD-domain-containing-protein
MDVASADDPAWVVKRWRRYGYDRLYVERPDGAKVGYWDLAADTAHPSAPGDEPLLLRAVTAWKDGDRGAAVPPEADPAPAAPVPWIDLATTPPGAAAREQAEAARAAAPIKTVLARVLGVHTDERAWRLGAVGEEQVAAQLAKVARNDARWCFLHAIPVGTRGSDIDHLVIGPGGVFTVNTKHHPGASIWVGGETLLVNGTRQPYVRNARHEAERAGRLLSAACGFPVHVSGLVVPVNTDEVVVKSQPAGVAVVPRRRLAGWLTRHGEIHPPATVESIFAMARRSTTWQA
>NZ_CP009896.1|WP_082003816.1|4999906_5000269_-|hypothetical-protein
MIDLADRFFAAAAAHDLDAVRVLYADDARIWHNWDDHEQDVDENLATLGSLPQRYDRFGYDAVRTVALADGFVRQHDIVVARGDRSARVPAILRGYVADGRITRIEEYFDLGQLAAVRAG
>NZ_CP009896.1|WP_162484134.1|5000273_5001380_-|alpha/beta-hydrolase
MERTFVGLPSLNLPRAGAGGHPCQGIYHRRAGTRPKVAVIATHYQIDFSEHYLASYLAERGFGFLGWNTRFRGDEAHFLLDHALSDIGVGVRWLREEAGAEAVILLGNSGGGSLMAAYQSQAVEPMVTALPGMQLARGVDDLPPADGYLSTAAHLGRPDVLTAWMDGAATDESDPLATDPELDLWNPANGPAYDDAFVARYRAAQEARNHRITAWVKDELARLTAAGYHDRPFSVARTWADPRMVDPTLEPTRREPNSCYAGVPERANRSVYGIASACTLRTWLSLWSLEDSQTRAHAHLPKITVPALVVNGNADTGVFPSDAQAIFDLLGTDDKESHELDADHYFLNEGARDEVADLIEAWLGKRYA
>NZ_CP009896.1|WP_052139074.1|5001425_5002937_-|MFS-transporter
MTPTPTNPASTGAAAPTRAGTYSSLRAAWIPLAALCLAFFVEMVDNTLLTIALPTIGRDLGSGTTALQWVTGAYSLTFGGLLLTAGSLADRLGRRRVLLVGLAVFGTISLAVVAVESAGELIALRAALGVAAAAMAPITNSLVFRLFDDQALRMRAMTLMIVVGMSGFILGPLLGGTALAHVRWEWLLVVNAPIALVAWIGVRVGVPADRPEDLTSDRLDLPGAVLSIAAIGFACYALTSGVEHGWSSAVTLGSVAGAVLALAGFVRHERRTPEPMLDLGVFSDRTVRGAALAQAGTSIALAGVMFGLILHFQYAYGWSPVRAGLANLPLIVTMIVATPLSEALARRLGHRIACLVGAGLLAAALAGLAWGVDHGYAAIAAAMVVLTIGLRTVMTICAVALVSAMPSNRTSLGAALNDTAQEVGTSVGTAVVGTLVAALVTASLPAGVWSSELVASFFHGERIIYGVLAVVVGVIAGWGALTLTDSRSVEEPEPEALDAAARL
>NZ_CP009896.1|WP_082003817.1|5003047_5003836_+|TetR/AcrR-family-transcriptional-regulator
MAAAPGRGDTPVTAGATQARGTARAGAARAGAARAGGGRRRASHSLEAVIGEAVALLDEAGEPALTFRALAARLGGGVASIYWYVANKDELLDRATDHVLAGVLVDTEGFTGSPDPIDDLRAIAVSLFGTIVERPWLAAYFMRDTATQPNGLLLYERMGQQVLRLGLTPRQSFHAVSAVLGFVIGIAADLGQQPPQEVLDGKVTRDDFLARYAAEWRALDPAAYPFLHVVVDEFADHDDADQFRAGLDLLLAGLRLQAQNPD
>NZ_CP009896.1|WP_038682114.1|5003855_5004473_-|TetR/AcrR-family-transcriptional-regulator
MTSTQAPRPTRRGRQTLEAIDAAARKVIAEKGFLKMTVADIVKEAGKSPASFYNYYDSKEALLEHWARQFQDEARERLAEAERVVGKDPRERVEAAARAHWETYRARLAEMVGVFQLAMINDEFAAVWDEICSEAEAGIARAVARAQERGFAPGADAALTARAIVAMLNMFCYENLANGRAARVDDEACITTLANAWYHAIYWIE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP009896_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009896_17

5350769-5350881

Orphan

Consensus_repeat	Method
GGCAGTTTCACCGCCTAGGCGGTGAAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009896_17

>merge|NZ_CP009896|17|5350769-5350881|CRISPRCasFinder
GGCAGTTTCACCGCCTAGGCGGTGAAACTCCCCCTAAGCACACCGAACTACCTGCGCCAAGGTCCAGTTTCGTTCGTTCAGTTCGGCAGTTTCACCGCCTAGGCGGTGAAACT

>NZ_CP009896|17|17|5350769-5350881|CRISPRCasFinder
GGCAGTTTCACCGCCTAGGCGGTGAAACT	CCCCCTAAGCACACCGAACTACCTGCGCCAAGGTCCAGTTTCGTTCGTTCAGTTC
GGCAGTTTCACCGCCTAGGCGGTGAAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009896.1\|WP_038682558.1\|5345856_5347386_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009896.1\|WP_052139469.1\|5360245_5361553_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|162098
NZ_CP009896.1\|WP_052139141.1\|5343750_5344281_+\|CAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|349398
NZ_CP009896.1\|WP_038682573.1\|5356336_5357269_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224662
NZ_CP009896.1\|WP_052139145.1\|5358391_5358973_+\|TIGR03086-family-protein	unknown	unknown	gnl\|CDD\|274424
NZ_CP009896.1\|WP_038682577.1\|5361561_5363034_-\|NAD-dependent-succinate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143421
NZ_CP009896.1\|WP_038682567.1\|5353431_5354028_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP009896.1\|WP_038682556.1\|5344835_5345798_-\|NADPH:quinone-oxidoreductase-family-protein	unknown	unknown	gnl\|CDD\|176203
NZ_CP009896.1\|WP_141267555.1\|5350907_5353433_-\|YegS/Rv2252/BmrU-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NZ_CP009896.1\|WP_075018426.1\|5343098_5343629_+\|CAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|349398
NZ_CP009896.1\|WP_038682554.1\|5341027_5343001_-\|peptidase-M13	unknown	unknown	gnl\|CDD\|226118
NZ_CP009896.1\|WP_038682561.1\|5348784_5349480_+\|pirin-family-protein	unknown	unknown	gnl\|CDD\|380375
NZ_CP009896.1\|WP_052139467.1\|5357360_5358386_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|236196
NZ_CP009896.1\|WP_038682569.1\|5354024_5355587_+\|glycerol-3-phosphate-dehydrogenase/oxidase	unknown	unknown	gnl\|CDD\|223651
NZ_CP009896.1\|WP_052139144.1\|5349956_5350634_-\|GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|234745
NZ_CP009896.1\|WP_038682563.1\|5349492_5349960_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP009896.1\|WP_038682575.1\|5358988_5360242_+\|low-temperature-requirement-protein-A	unknown	unknown	gnl\|CDD\|377704
NZ_CP009896.1\|WP_038682559.1\|5347375_5348722_-\|beta-glucosidase	unknown	unknown	gnl\|CDD\|274539
NZ_CP009896.1\|WP_052139142.1\|5344325_5344814_+\|CAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|349398
NZ_CP009896.1\|WP_038682571.1\|5355615_5356188_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP009896.1\|WP_052139469.1\|5360245_5361553_-\|MFS-transporter	gnl\|CDD\|162098	TIGR00900, multidrug_transporter, H+ Antiporter protein. [Transport and binding proteins, Cations and iron carrying compounds].	7.00622e-54
NZ_CP009896.1\|WP_052139141.1\|5343750_5344281_+\|CAP-domain-containing-protein	gnl\|CDD\|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	1.57452e-33
NZ_CP009896.1\|WP_038682573.1\|5356336_5357269_+\|hypothetical-protein	gnl\|CDD\|224662	COG1748, LYS9, Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism].	2.2262e-16
NZ_CP009896.1\|WP_052139145.1\|5358391_5358973_+\|TIGR03086-family-protein	gnl\|CDD\|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	6.90075e-17
NZ_CP009896.1\|WP_038682577.1\|5361561_5363034_-\|NAD-dependent-succinate-semialdehyde-dehydrogenase	gnl\|CDD\|143421	cd07103, ALDH_F5_SSADH_GabD, Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like. Succinate-semialdehyde dehydrogenase, mitochondrial (SSADH, GabD, EC=1.2.1.24) catalyzes the NAD+-dependent oxidation of succinate semialdehyde (SSA) to succinate. This group includes the human aldehyde dehydrogenase family 5 member A1 (ALDH5A1) which is a mitochondrial homotetramer that converts SSA to succinate in the last step of 4-aminobutyric acid (GABA) catabolism. This CD also includes the Arabidopsis SSADH gene product ALDH5F1. Mutations in this gene result in the accumulation of H2O2, suggesting a role in plant defense against the environmental stress of elevated reactive oxygen species.	0
NZ_CP009896.1\|WP_038682567.1\|5353431_5354028_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.27024e-08
NZ_CP009896.1\|WP_038682556.1\|5344835_5345798_-\|NADPH:quinone-oxidoreductase-family-protein	gnl\|CDD\|176203	cd08241, QOR1, Quinone oxidoreductase (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.72396e-131
NZ_CP009896.1\|WP_141267555.1\|5350907_5353433_-\|YegS/Rv2252/BmrU-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	4.15978e-47
NZ_CP009896.1\|WP_075018426.1\|5343098_5343629_+\|CAP-domain-containing-protein	gnl\|CDD\|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	2.96087e-35
NZ_CP009896.1\|WP_038682554.1\|5341027_5343001_-\|peptidase-M13	gnl\|CDD\|226118	COG3590, PepO, Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP009896.1\|WP_038682561.1\|5348784_5349480_+\|pirin-family-protein	gnl\|CDD\|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	8.72664e-42
NZ_CP009896.1\|WP_052139467.1\|5357360_5358386_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|236196	PRK08241, PRK08241, RNA polymerase subunit sigma-70.	2.56859e-157
NZ_CP009896.1\|WP_038682569.1\|5354024_5355587_+\|glycerol-3-phosphate-dehydrogenase/oxidase	gnl\|CDD\|223651	COG0578, GlpA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	3.16288e-120
NZ_CP009896.1\|WP_052139144.1\|5349956_5350634_-\|GTP-cyclohydrolase-II	gnl\|CDD\|234745	PRK00393, ribA, GTP cyclohydrolase II RibA.	5.84583e-107
NZ_CP009896.1\|WP_038682563.1\|5349492_5349960_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	5.38223e-18
NZ_CP009896.1\|WP_038682575.1\|5358988_5360242_+\|low-temperature-requirement-protein-A	gnl\|CDD\|377704	pfam06772, LtrA, Bacterial low temperature requirement A protein (LtrA). This family consists of several bacteria specific low temperature requirement A (LtrA) protein sequences which have been found to be essential for growth at low temperatures in Listeria monocytogenes.	7.74498e-78
NZ_CP009896.1\|WP_038682559.1\|5347375_5348722_-\|beta-glucosidase	gnl\|CDD\|274539	TIGR03356, BGL, beta-galactosidase.	0
NZ_CP009896.1\|WP_052139142.1\|5344325_5344814_+\|CAP-domain-containing-protein	gnl\|CDD\|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	1.74856e-29
NZ_CP009896.1\|WP_038682571.1\|5355615_5356188_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.26166e-10

>NZ_CP009896.1|WP_052139144.1|5349956_5350634_-|GTP-cyclohydrolase-II
MTTHCLQLRRPDAARLPRAEVRTQVVIPLRFPDGYATTADVLTFHHLVDGKEHLLLGLGDWRARVAQLPLGGDAPLVRPHSECLTGDVFGSERCDCGPQLREAVERITAEGGFLLYLRQEGRGIGLYEKLDAYALQDAGLDTYAANRALGRGEDERDYSAAVQMLLAVGADRIRLLSNNPDKAAQLEEHGVAVDERVPTGVHLSAANRRYLTVKRDHTAHTLDIA
>NZ_CP009896.1|WP_038682563.1|5349492_5349960_-|MarR-family-transcriptional-regulator
MSEPRWLDDDELAAWLPLVRLVQALPQALDRGLREEAGITHTYYAMLANLSAAPDRTLTMGELARLTATSPSRLTHAISVLEGRGWVTRRQCPNDRRSQFAVLTDEGLALLQRIAPAHLAQVRELVFDRLTPEQVRSLGEIAGALVGGIDELGEG
>NZ_CP009896.1|WP_038682561.1|5348784_5349480_+|pirin-family-protein
MSVEIRRGSARFLERAPGRLSQHGFSFGAHYDPERLSFGPMVCHDDHVLGPGTGFEEHPHETLEIVTWVVSGALVHRDATGTDETLGAGACGVLSAGSGTRHSEIASADGPARFVQVWLTPDPDAADAPPRYRRATVDAAPGAGPVRLVGDGGPLAVGVRGAALDVVRLAAGETVTLPAAARMHAFVTTGALLRSSLAEPLAAGDAFCMTDEGAHDVTAAVPTELLVWTFA
>NZ_CP009896.1|WP_038682559.1|5347375_5348722_-|beta-glucosidase
MGDLAGRFPAGFRFGTSTAAYQIEGAADEDGRGRSIWDTFTAEPGRIVDGSSGAVACDHYHRWPEDVELMRRLGAPGYRFSIAWPRIQPTGRGAVNQAGLDYYDRLVDGLLAAGIEPMATLYHWDLPQSLEDDGGWLNRATIDRFADYTAIVGERLADRVVDWVPVNEPSVVTLMGYAVPFHAPGRSLMFDALPVGHHLLVAHGRAAIALRAAGATSVGCANNHAPIWPASDDPADVGAAKLFDALWNGHYLEGMLLGRYSDDLMMLLEQHVRDGDFATMRQPLDFYGVNYYNPMRIAAADENAELPFEFREVLGYPVTDFGWPVVPDALREWLIMFRARFRAAVPPIVITESGCSYAVGPDEHGVVDDHQRVDYHALHLTAVAEAIERGVDVRGYYAWSLIDNFEWSEGYTQRFGLVHVDYETQKRTPKRSFSWYADLVAEHARLTT
>NZ_CP009896.1|WP_038682558.1|5345856_5347386_+|hypothetical-protein
MSDWTDWKQNRRLEETEAQLAAERSARSRLADQMRTQQGNLQGQIDRLTRAFVALVEHEDIRAELGQYADAAACRRYAREVVSTVVATGTAALRGSAEPDDVPGYWLAPAARGIVRIAQGEPGGPELLAEATHRDPRRTTLLLTLLGALTRDPRWTGGQDLTRVLPDRPEVSHAQRQVWLAVADGRVAPDGDALVTALRTQVAATGSAGLDEVAAWLEEIAPPDSRHLAVERATAQLAALQQVLQTGGATAQAPTGDPIGDQTDNQADEPAEDPLADCVRSLVDEGSPGEAEILDRMATVRADLGFIDERTASLAPAWSGTAGDVVRLLLDDLAQPAGSPRHTLAQQVLAPTLGAIGDELAAQAAVPPPETRTVEVAGEVLTVTRDGVAGDWQARVGAALERRYPVDRRLLPGGGALLALAVVLAGLGFVAGGWFVLAAAALVGGGALVGTALLKRRALAENRTSTIAATERRIAQERVTLDQHRERSITASTRARELHRGVGTAALRS
>NZ_CP009896.1|WP_038682556.1|5344835_5345798_-|NADPH:quinone-oxidoreductase-family-protein
MRAVQVVTTTGPADIVVQEVPDPTPGPEEVLVEVHAVGVSFPDLLLSRGEYQLRPDPPFTLGVDYAGVVVSGPGFEPGQRVAGVGGYGGAAELVAGHRDSVFALPDSITFEEAVALPMNYLTALFALDERGGVRPGETVLVHGAAGGVGTATLQVARGLGARTIAVVSTDEKAAFAKAAGADETVLFDGFKDAVAGLTGGKGVDVVLDVVGGSAFTDSLRSLAPQGRLLVVGFAAGEGIPEVKVNRLLLNNIDVRGVGWGAYAFVRPGYLQEQWTQLVPMIESGAVKPPVGKVYPLEEFGQALLDMDARAALGKLVVSVR
>NZ_CP009896.1|WP_052139142.1|5344325_5344814_+|CAP-domain-containing-protein
MRLAALLPTALAAALLLVPTLPAHPADAGPSATAASPLEQRLAAHVNRARSRQGCRPLKHQAALHGSARAHSALMARHRRLSHQLPGEAALGTRLANAGYPGSRRMGEVIAAGPMSAQRTLRMWLGSPPHRRLLLDCRFRLLGVGVVESGPGQRWWTIDLVR
>NZ_CP009896.1|WP_052139141.1|5343750_5344281_+|CAP-domain-containing-protein
MPRRRSTGLLAGVLSLLTVLATPWLAAGSTGTAPAAPASPSGRGYAVDTSFEARVITLTNRRRERAGCRPLRLSLPLQAAARSHSGAMARATTMAHELPGELGLVRRVVQAGYTPWRRLAENLGAGFVSPRSVVRAWMRSAGHRRNLLDCRLREVGVGVVRAGSGQLWWTQDFGRR
>NZ_CP009896.1|WP_075018426.1|5343098_5343629_+|CAP-domain-containing-protein
MKPSLGLLPGLALCLTLGLTLSIGPGAPAPASAAPVSTTPGVPARLLVQRLLEDRVLALTNQQRRKHGCGALRNSAPLRKAARGHTVSMALAGTMSHQLPGEARFSSRITQSGYKGWRIVAENIARGFSTPNDVVAAWMRSPSHRRNILNCRLRDLGVGVVLQSGQLWWTQDFGVR
>NZ_CP009896.1|WP_038682554.1|5341027_5343001_-|peptidase-M13
MSILDDARPGMDPDIRPQDDLFGHVNGTWLDEAEIPSDRSSWGPFVQLADQAEEDVKAIITELAEGVSTGATDGGDDARKIADLFNSFMDTERVEAAGLAPVQPMVDAVAGLRDVRDVAAFLGEFERIGGYGLFGSYVDTDDRQSDRYLFHLAQGGLGLPDESYYRDDKFAEIREAYVGYLTRLLTLGGHADPTGAAQRILELDTDLAKGHWERADTRDVQKTYNRLTADELEALCPAFDWDAYITNLGGHLDGEHATIAEVVVRQPSYLQHLSGVLEATPIETWRDWFLSRVLRSAAPYLADEFVQTNFDFYGRTLSGTPELRARWKRAVSFVEGAMGEAVGKEYVARHFPPTSKAMMDELVANLLAAYRQSISKLDWMTDETKLRAYEKIETFRPKIGYPERFRDYSALVVVPDDLVANAQAAAGFETDRQLAKIGSPVDRDEWFMLPQTVNAYYNPGTNEICFPAGILQKPFFSPDALAAENYGGIGAVIGHEVGHGFDDQGAQYDGEGNLNDWWTADDKAAFEVKSKALIAQYDGFAPRNLPGEHVNGALTVGENIGDLGGLTIAHTAFLIAEAAAGREASDDDRKNLFFNWAYVWRTKRRLEQEQQYLTIDPHSPPEFRANIVRNLDEFHEVFATAPGDGLWLDPADRVRIW
>NZ_CP009896.1|WP_141267555.1|5350907_5353433_-|YegS/Rv2252/BmrU-family-lipid-kinase
MCNTVTHDHRAPRRPAARDARHALGRPGPRHRPPGRRARARRPGLPDPGHPRPHRRRGPRLAAHRRARGRAARPRRRRERGARRRAAPAAHARQVDAGPAPPAGRRPRRRAGRRRPPGLARRGRRGARPRRRAADRGRAVRWRHRGHRWPRRRCDRVRGRRLARPRPDARPARARPGLVDRDPRAGSARPRGRGAPRRARHDARPLPPVVRVRHHRRLRRDPLQRSVECGLRPLRRDGRRPARRHARRRGPARQCPRQRERPRPARALPRLRGRPRRDHRGDGAGPAAARGQAVRGLALGLLRRGRRCDADARPGRPAAHGHPALRRERDRDQPRRPVRDRRRGERRLPDGRRLRGDRGCRRREAGRGHRGAERPRRDRGGRRPRRGVGARPVQRAVPARQPARRRRARRDARDRDLLEQPREPLRPGEGRAGGEPRRGHDGALPHLARLPDRLLALLHRRRPRGRRPARPLAARQGRRQRGDRRRQRRDHPPPRGRHRPQALPDRRDRRGRRRGAARRQGDRRPRRDPQPRGADPVTTRSFAFLVNPSSGGGAAPRVVVPLARALREAGAEVEVTYTTSAAETPALVEAAVAAGAVVVSVGGDGMLSSVAGSVASLGGVLAMVPAGRGNDFARMLEIPHDTAAQAALLLSGAERAIDLLRVTQADGSSYVVAGSVYAGVDARAAEIVDRSHWLPSKLQYPYAAVRALATYRPVECVLEVDGVRTEHQAATVVVANSSFYGKGMAIAPAAVVDDGLLDVVVIEAASHLDLIRSLPKVYDGSHVALDEVTVLTGRQVRLSGRHRGGAAVPVGADGEALGALPAGADLPLTVELLPGAVRVLA
>NZ_CP009896.1|WP_038682567.1|5353431_5354028_+|TetR/AcrR-family-transcriptional-regulator
MSSHRHNGESESSPRDGYLDAARECILDVGWRRTTLTEVARRAGVSRMTIYRAWSDMPALLADLMTREWGALVAGRLDEAAPPTPGSIADTVVATVWALRENELFTRIVELDPELILPYLLSRRGRSQELILEVLGAAIAAGQSAGAIRDGAPQAIARGLLLAAHGFVLSAHTMIDDVVDEAALDTELHTLVVRSLQP
>NZ_CP009896.1|WP_038682569.1|5354024_5355587_+|glycerol-3-phosphate-dehydrogenase/oxidase
MSAAPTRITPGLDGVPAAVDVVVIGLGVTGAGVALDAVSRGLTVLAVDAHDLAFGTSRFSSKLVHGGLRYLASGQVGIAHESAVERGILMETTAPHLTRPLPSIIPLAAGVSRPMGTLAGAGFVGGDLLRRAAGTSSDTLPRPRRLSAAETRRLAPPLRTDGLRGAYLGWDGQLEDDARLVTAIARTAAERGAHVRTHARAVSATGQQVVLRDERTGATTTVHAQAVVNATGVWAGELVDDVRLRPSRGTHLVLRGSALPGLDVAVFAPIPGETNRFVLVLPQPDGQLYVGLTDEPVDGPVPDVAEPTEVEIGFLLDVVAASFARPLRRSDVVGAFAGLRPLLDSGDDSTADLSRKHAVLTSRTGVVTIVGGKLTTYRRMAEDAVDAAVAAAGLGATAGPCVTATLPLAGAAPRTELADRAAQAGSAGEARLIRRYGADAGLVLDAAVAASGWSPAELLAPIAEGVPTVAAELFFGVTHEGAADVADLLDRRTRIGLVPADRARAVPVAERVLAATRATP
>NZ_CP009896.1|WP_038682571.1|5355615_5356188_-|TetR/AcrR-family-transcriptional-regulator
MAWDTEATRSRLLDAGVRQFAALGFAGARIDAIARDAGINKERVYRYFGDKQGLFSAVLEHELDALFDGLEVEVTTPEGIGEFTGRMFDRCLARPELPRLLIWESLELEAPVAADSRQPVCAVNATRICDAVRGLGRVESEHLLLTAISVVVGWWGLSRLAEVVLTDPDAVAVRRQMVVAQMTALAREAG
>NZ_CP009896.1|WP_038682573.1|5356336_5357269_+|hypothetical-protein
MKALVLGARGAVGQVITTELRRRGHDVTPAGRTAPPGGVAVDLSRPEDAAVRAALVRAAEGHDVVVNAAGVESTVLAAAGAPVVVDISATGSYLAALRAAAPAAGTVVLGAGLAPGLSTVLVTALDRRPDDQVDVGVLLGTAERHGDAAVQWTADLVGAPVHAPPEGGRVLNLRTRRRLVGPDGRTRTYLRADFPDHVLVGERLGVAIRSHLTLSSRAATAGLGLAARTGAGGLLRYSPHFGSAAWHVVAVNRRTGQTLGAAGTGQSHATGVLTVLAAERAVAGPARGPVTMADLVDRTAALDRLAETES
>NZ_CP009896.1|WP_052139467.1|5357360_5358386_+|sigma-70-family-RNA-polymerase-sigma-factor
MVTEQTQAAAASDELADFDTLTGRYQRELMAHCYRMSGSVHEAEDLVQETFLRAWKASASFQGRSSVRTWLYKIATNVCLTNLESKPRRPLPTGLGTADSAPSDELLEDHEVPWLEPIPDAAVEVAERDTIRLAFVAALQHLPARQRAVLILRDVLRWSAAETATALDTTTAAVNSALQRAHAQLAERGLTPETVEPDLDPAQRQLLDAYLAAFWRKDIDQIVQLLKYDATWDMPPFLNHYRGATAIAELIGTKCPGGCNDMPMVETIANGQPAFGLYMRHPEGHFEPFHLQVLQMTGTGADLRVEHVTAFFDHRLFARFGLPERLPADYVPVPDAPACAG
>NZ_CP009896.1|WP_052139145.1|5358391_5358973_+|TIGR03086-family-protein
MTAEPTPAGLVAGLDVLQRALDYTRATLGTITCADVDRPTPCAGWDLADLLAHMEDALDAFAEAADGTVALHSAAPAPLEARVTSLQVKACGLLAAWMHATSPYVDVGGHPLPVDAVARLAAVEIAVHGWDVGQATGRGGPLPERLAAELLPTALRIALEGDDRFALPVPVATEAPAADHVLALLGRRPGTRS
>NZ_CP009896.1|WP_038682575.1|5358988_5360242_+|low-temperature-requirement-protein-A
MPEQTAAPHVRHRPRRMLGRDPHESHRAATPLELLFDLAFVVAFGTAANELAHAVAEEHVWAGVLGFCFATFGISWAWINFTWFASAYDTDDWIYRLTTMLQMVGVLVFAIGLKPMFTSIYEHGETLDNDVMVWGYVIMRAAMVLQWWRAGRHDAARRGACQVYIVSILVAQVAWCALAIVDLPVATTFVLMAIPFLIEIGGPAYAETRRGGTPWHAHHIAERYSLMVIIALGEGMIGTMASISELSAEGLTWDIGLLALAGTALTFGIWWSYFVVPFADILHAHRERSFSFGYGHMPLFGSIVAVGAGLHVGAYYLGHEFHIGLVGAVLAAAIPVALFTAFLYAGYTILTRNFDSLHLLLIAGSAALVIASVLLATAGVSLVWCLLVLALTPWVTVVGYELRGYRHNLEVLGSLDE
>NZ_CP009896.1|WP_052139469.1|5360245_5361553_-|MFS-transporter
MVPPAPAPRGWLRAFRPFRHASYRRLGSALVLTSFGGGVWVVALVWEVIRIGGGASALSLVTTAGAVGVLIPALLGGVVADRVPQKLILLATTSVELAGMVLVAVLSYADLTRLWHLAVVAAVAGMAMAFYYPAYSAWLPALVPEEDLLAVNGFEGMVRPTIGQALGPAVAGGVVGAASSSAAITVAAVAYLGGLLVLTRVPLTAIRRERPAATGDDAEPPPAALATALADIREGFAYMVRTPWLLASLLFASVMILVIMGPLEVLVPFLIKDDLGGGPGDHALVMAGFGIGGAVGSLVTASRPMPRRYLTWMMLMWGAGCLPFLVVGFATAVWQVVAAATVVGALFAAPMVLWGTLLQRRVPPELLGRVASLDFFVSISLMPVSMALAGPVAELIGLEATFTIAAVVPVVVAVVAVVAARLPADELAHPLRDEG
>NZ_CP009896.1|WP_038682577.1|5361561_5363034_-|NAD-dependent-succinate-semialdehyde-dehydrogenase
MSFRERLHHLLPESRRQLYVGGAWVPSGSGARFDVLDPADGSVLADVADGTLDDARAALDAAAGAQEAWAATAPRERGEILRRTFGLVTQHADDVALVMSLEMGKPIAEAKGEVTYGAEFLRWFSEEAVRIHGRWMQNPAGGSRLLTVRKPVGPCLFITPWNFPLAMGTRKIGPAIAAGCTMVVKPAGQTPLTMLLLAALLEEAGLPAGVLNVVTTTDSGGLSSTLQADARLRKVSFTGSTSVGKRIVEQSAGELQRVSMELGGNAPFLVFADADLDAAVEGAMIAKMRNMGEACTSANRFLVEASVAEEFGTRLAERMGGLKVGRGQDVGVQVGPLIDDKAVSSVAALVDDAVDRGARLLTGGRAPEGGAGFFYPPTVLADVPADADAVRNEIFGPVAPITTFADEDEAIRLANATEYGLAAYAYTRDLARTIRLAERLETGMLGINTGLVSNPAAPFGGVKASGFGREGGFEGIEEYLDTTYVALPVT

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP009896_14	14.1\|4937680\|45\|NZ_CP009896\|CRISPRCasFinder	4937680-4937724	45	AY328852	Vibrio parahaemolyticus phage VP16T, partial sequence	34753-34797	12	0.733

1. spacer 14.1|4937680|45|NZ_CP009896|CRISPRCasFinder matches to AY328852 (Vibrio parahaemolyticus phage VP16T, partial sequence) position: , mismatch: 12, identity: 0.733

tggccgtagggctgctgcggctgctgcggctgctgcggcggctgg	CRISPR spacer
tactgctgctgttgctgcggctgctgcggctgttgctgcggctgt	Protospacer
*. .  *.  *.********************.*** *******

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

373378 : 383913

Gordonia_phage(30.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052138124.1\|373378_373771_+	hypothetical protein	C5IHK2	Burkholderia_virus	2.3e-11	36.0
WP_052138125.1\|373770_374724_+	DUF2303 family protein	I6WAZ8	Burkholderia_virus	1.9e-30	37.6
WP_052138126.1\|374745_375699_+	hypothetical protein	A0A2D0ZWQ3	Rhodococcus_phage	3.0e-44	42.9
WP_038676190.1\|375784_376234_+	hypothetical protein	NA	NA	NA	NA
WP_158510154.1\|376230_376401_+	hypothetical protein	NA	NA	NA	NA
WP_158510155.1\|376397_376562_+	hypothetical protein	NA	NA	NA	NA
WP_038676192.1\|376660_377542_+	hypothetical protein	V5R922	Arthrobacter_phage	5.4e-32	36.3
WP_052138127.1\|377538_378528_+	phage recombination protein Bet	A0A1B3AYQ4	Gordonia_phage	1.2e-48	38.1
WP_052138128.1\|378527_378902_+	DUF3850 domain-containing protein	F6LQC3	Bdellovibrio_phage	7.4e-07	58.5
WP_038676194.1\|378898_379177_+	hypothetical protein	NA	NA	NA	NA
WP_038676195.1\|379336_379690_+	hypothetical protein	NA	NA	NA	NA
WP_158510156.1\|379686_379857_+	hypothetical protein	NA	NA	NA	NA
WP_038676198.1\|379856_380222_+	hypothetical protein	A0A1D8ETS9	Propionibacterium_phage	1.8e-29	58.9
WP_038676200.1\|380218_380557_+	hypothetical protein	NA	NA	NA	NA
WP_038676202.1\|380550_382344_+	hypothetical protein	A0A142KB94	Gordonia_phage	8.7e-130	45.8
WP_038676204.1\|382340_382961_+	hypothetical protein	A0A2D2W3D2	Mycobacterium_phage	9.1e-10	33.8
WP_038676206.1\|382957_383548_+	hypothetical protein	NA	NA	NA	NA
WP_038676208.1\|383544_383913_+	DUF4326 domain-containing protein	A0A161HSY5	Gordonia_phage	6.8e-21	45.9

DBSCAN-SWA_2

676001 : 682898

Enterobacteria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038676598.1\|676001_676553_+	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	3.6e-10	30.4
WP_038676600.1\|676717_678784_+	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	H8ZJI5	Ostreococcus_tauri_virus	1.8e-110	46.7
WP_038676602.1\|678791_679412_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	3.0e-45	51.9
WP_038683362.1\|679427_680828_-	sugar nucleotide-binding protein	A0A1D7XFA3	Escherichia_phage	6.0e-25	37.5
WP_082003903.1\|680836_682012_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	6.9e-75	45.6
WP_038676606.1\|681998_682898_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.6e-84	53.5

DBSCAN-SWA_3

854618 : 859973

Mycobacterium_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038676844.1\|854618_854858_-	hypothetical protein	A0A2L1IX87	Mycobacterium_phage	4.4e-05	41.8
WP_038676846.1\|854854_855265_-	hypothetical protein	NA	NA	NA	NA
WP_141267753.1\|855385_855748_-	hypothetical protein	A0A142KAB1	Gordonia_phage	1.2e-17	50.0
WP_141267751.1\|855763_856246_-	hypothetical protein	NA	NA	NA	NA
WP_052138223.1\|856239_856614_-	hypothetical protein	A0A142UM69	Mycobacterium_phage	7.6e-12	46.5
WP_141267749.1\|856610_857117_-	hypothetical protein	G8I6T7	Mycobacterium_virus	4.3e-26	41.7
WP_052138225.1\|857166_857910_-	hypothetical protein	A5YK40	Mycobacterium_phage	3.0e-52	49.4
WP_158510172.1\|857906_858059_-	hypothetical protein	NA	NA	NA	NA
WP_038676850.1\|858058_858253_-	hypothetical protein	NA	NA	NA	NA
WP_038676852.1\|858404_858950_-	hypothetical protein	G9FH01	Rhodococcus_phage	1.0e-28	43.4
WP_141267747.1\|858949_859129_-	hypothetical protein	NA	NA	NA	NA
WP_038683454.1\|859139_859973_-	hypothetical protein	G9FH00	Rhodococcus_phage	3.2e-58	48.3

DBSCAN-SWA_4

3404914 : 3412222

Streptomyces_phage(66.67%)

portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082003977.1\|3404914_3405178_+	hypothetical protein	A0A0A7RVT7	Mycobacterium_phage	3.2e-09	46.2
WP_052138790.1\|3405340_3405883_+	hypothetical protein	A0A1C9EHY3	Gordonia_phage	5.0e-20	42.4
WP_038679817.1\|3407632_3409021_+\|portal	phage portal protein	D7NW49	Streptomyces_phage	3.3e-28	25.8
WP_038679818.1\|3409001_3410375_+	hypothetical protein	A0A2H5BLR1	Streptomyces_phage	2.5e-12	31.0
WP_052138791.1\|3410568_3411189_+	hypothetical protein	K4HYD2	Streptomyces_phage	1.9e-07	41.1
WP_038679819.1\|3411229_3412222_+	hypothetical protein	K4I030	Streptomyces_phage	3.3e-86	53.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP009896

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection