CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP012978	Endosymbiont of unidentified scaly snail isolate Monju	12 crisprs	cas3,DEDDh,DinG,csa3,cas6,WYL,cas8c,cas7,cas4,cas1,cas2	5	7	2	0

1. NZ_AP012978

CRISPR-Cas detection and classification

Crispr_ID: NZ_AP012978_1

• CRISPR_ID: NZ_AP012978_1
• CRISPR_location: 487673-487761
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP012978_1

Consensus_repeat	Method
GTTCGCGGCGGGGACGCCGCTCCCAC	CRISPRCasFinder

spacers of NZ_AP012978_1

>1.1|487699|37|NZ_AP012978|CRISPRCasFinder
GGGTAGGAGGCCCGTCCCCGGGCCGAATGATGCACGG

CRISPR arrays and Neighbor proteins around NZ_AP012978_1

CRISPR arrays

The CRISPR arrays of NZ_AP012978_1

>merge|NZ_AP012978|1|487673-487761|CRISPRCasFinder
GTTCGCGGCGGGGACGCCGCTCCCACGGGTAGGAGGCCCGTCCCCGGGCCGAATGATGCACGGGTTCGCGGCGGGGACGCCGCTCCCAC

>NZ_AP012978|1|1|487673-487761|CRISPRCasFinder
GTTCGCGGCGGGGACGCCGCTCCCAC	GGGTAGGAGGCCCGTCCCCGGGCCGAATGATGCACGG
GTTCGCGGCGGGGACGCCGCTCCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_043107113.1|487776_488967_+|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	unknown	unknown	gnl|CDD|235441
NZ_AP012978.1|WP_043107112.1|484840_487618_+|preprotein-translocase-subunit-SecA	unknown	unknown	gnl|CDD|237259
NZ_AP012978.1|WP_043107103.1|475512_476940_+|UDP-N-acetylmuramate--L-alanine-ligase	unknown	unknown	gnl|CDD|234757
NZ_AP012978.1|WP_043107119.1|490608_491376_-|cell-division-protein-ZapD	unknown	unknown	gnl|CDD|377767
NZ_AP012978.1|WP_043107118.1|489898_490285_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043109082.1|492983_494216_-|type-II-secretion-system-F-family-protein	unknown	unknown	gnl|CDD|224376
NZ_AP012978.1|WP_148307615.1|495415_496635_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
NZ_AP012978.1|WP_070104708.1|478906_479686_+|FtsQ-type-POTRA-domain-containing-protein	unknown	unknown	gnl|CDD|224505
NZ_AP012978.1|WP_043107120.1|491475_492078_-|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|234620
NZ_AP012978.1|WP_081999774.1|490432_490612_-|DNA-gyrase-inhibitor-YacG	unknown	unknown	gnl|CDD|367713
NZ_AP012978.1|WP_043107111.1|483812_484727_+|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_AP012978.1|WP_043107105.1|477984_478917_+|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234948
NZ_AP012978.1|WP_043107106.1|479685_480921_+|cell-division-protein-FtsA	unknown	unknown	gnl|CDD|273483
NZ_AP012978.1|WP_043107110.1|483262_483715_-|DUF721-domain-containing-protein	unknown	unknown	gnl|CDD|377496
NZ_AP012978.1|WP_043107116.1|488966_489902_+|Nudix-family-hydrolase	unknown	unknown	gnl|CDD|236361
NZ_AP012978.1|WP_043107104.1|477091_477988_+|UDP-N-acetylmuramate-dehydrogenase	unknown	unknown	gnl|CDD|237553
NZ_AP012978.1|WP_171816164.1|492082_492814_-|prepilin-peptidase	unknown	unknown	gnl|CDD|224900
NZ_AP012978.1|WP_043107108.1|482344_483256_+|UDP-3-O-acyl-N-acetylglucosamine-deacetylase	unknown	unknown	gnl|CDD|237294
NZ_AP012978.1|WP_081999775.1|494218_495391_-|type-IV-A-pilus-assembly-ATPase-PilB	unknown	unknown	gnl|CDD|274186
NZ_AP012978.1|WP_043107107.1|480985_482176_+|cell-division-protein-FtsZ	unknown	unknown	gnl|CDD|236468

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_043107113.1|487776_488967_+|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	gnl|CDD|235441	PRK05388, argJ, bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ.	0
NZ_AP012978.1|WP_043107112.1|484840_487618_+|preprotein-translocase-subunit-SecA	gnl|CDD|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_AP012978.1|WP_043107103.1|475512_476940_+|UDP-N-acetylmuramate--L-alanine-ligase	gnl|CDD|234757	PRK00421, murC, UDP-N-acetylmuramate--L-alanine ligase; Provisional.	0
NZ_AP012978.1|WP_043107119.1|490608_491376_-|cell-division-protein-ZapD	gnl|CDD|377767	pfam07072, ZapD, Cell division protein. Cell division protein ZapD enhances FtsZ-ring assembly. It directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.	3.14526e-91
NZ_AP012978.1|WP_043109082.1|492983_494216_-|type-II-secretion-system-F-family-protein	gnl|CDD|224376	COG1459, PulF, Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion].	3.33715e-152
NZ_AP012978.1|WP_148307615.1|495415_496635_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	7.01174e-123
NZ_AP012978.1|WP_070104708.1|478906_479686_+|FtsQ-type-POTRA-domain-containing-protein	gnl|CDD|224505	COG1589, FtsQ, Cell division septal protein [Cell envelope biogenesis, outer membrane].	5.76499e-41
NZ_AP012978.1|WP_043107120.1|491475_492078_-|dephospho-CoA-kinase	gnl|CDD|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	4.39125e-94
NZ_AP012978.1|WP_081999774.1|490432_490612_-|DNA-gyrase-inhibitor-YacG	gnl|CDD|367713	pfam03884, YacG, DNA gyrase inhibitor YacG. YacG inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. It acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. YacG has been shown to bind zinc and contains the structural motifs typical of zinc-binding proteins. The conserved four cysteine motif in this protein (-C-X(2)-C-X(15)-C-X(3)-C-) is not found in other zinc-binding proteins with known structures.	7.30336e-25
NZ_AP012978.1|WP_043107111.1|483812_484727_+|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	2.22251e-48
NZ_AP012978.1|WP_043107105.1|477984_478917_+|D-alanine--D-alanine-ligase	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.53037e-171
NZ_AP012978.1|WP_043107106.1|479685_480921_+|cell-division-protein-FtsA	gnl|CDD|273483	TIGR01174, Cell_division_protein_FtsA, cell division protein FtsA. This bacterial cell division protein interacts with FtsZ, the bacterial homolog of tubulin. It is an ATP-binding protein and shows structural similarities to actin and heat shock cognate protein 70. [Cellular processes, Cell division].	0
NZ_AP012978.1|WP_043107110.1|483262_483715_-|DUF721-domain-containing-protein	gnl|CDD|377496	pfam05258, DUF721, Protein of unknown function (DUF721). This family contains several actinomycete proteins of unknown function.	2.03241e-08
NZ_AP012978.1|WP_043107116.1|488966_489902_+|Nudix-family-hydrolase	gnl|CDD|236361	PRK08999, PRK08999, Nudix family hydrolase.	4.59565e-138
NZ_AP012978.1|WP_043107104.1|477091_477988_+|UDP-N-acetylmuramate-dehydrogenase	gnl|CDD|237553	PRK13905, murB, UDP-N-acetylmuramate dehydrogenase.	2.62017e-155
NZ_AP012978.1|WP_171816164.1|492082_492814_-|prepilin-peptidase	gnl|CDD|224900	COG1989, PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	4.21591e-45
NZ_AP012978.1|WP_043107108.1|482344_483256_+|UDP-3-O-acyl-N-acetylglucosamine-deacetylase	gnl|CDD|237294	PRK13186, lpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase.	0
NZ_AP012978.1|WP_081999775.1|494218_495391_-|type-IV-A-pilus-assembly-ATPase-PilB	gnl|CDD|274186	TIGR02538, Type_IV_pilus_assembly_protein_PilF, type IV-A pilus assembly ATPase PilB. This model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems. [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking].	0
NZ_AP012978.1|WP_043107107.1|480985_482176_+|cell-division-protein-FtsZ	gnl|CDD|236468	PRK09330, PRK09330, cell division protein FtsZ; Validated.	0

Protein sequences

>NZ_AP012978.1|WP_043107112.1|484840_487618_+|preprotein-translocase-subunit-SecA
MFNKVLKKVFGSRNDRLIKRMQKKVAQINAALRGKTGEFRERLEKGETLDDLLPEAFAVVREAGRRVLGMRHFDVQLIGGMVLHEGKIAEMRTGEGKTLVATLAAYLNGLSGKGVHVVTVNDYLARRDAEWMGRLYHFLGLSTGVINSSGGQGPDSASYLFDPDWDEQQGGYRHLRPVTRRQAYDADITYGTNNEYGFDYLRDNMAFSADQRVQRRNYAIVDEVDSILIDEARTPLIISGPAEDSSELYIKINAIPPKLTRQDPITNEEGKPDYGPGDYAVDEKARQIFLSDQGHEKVERMLVEMGLLDEQESLYDPSNIMLMHHVMAALRAHALFQKNVDYIVRDGQVIIVDEFTGRTMPGRRWSEGLHQAVEAKEGVPIQQENQTLASITFQNFFRLYDKLAGMTGTADTEAYEFQQIYGLEVVVIPPNKPTLREDQTDLVYLTQKEKFAAIVEDIRDCVQRGQPVLVGTASIEVSELVSRLLEKEGIPHQVLNAKQHEREALIVAEAGRPGAVTIATNMAGRGTDIVLGGNLEVEIAQLGPDATEEQIEALKKDWEERHRKVLEAGGLRVIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDNLMRIFASERVSALMQKLGMQEGEAIEHPWVNRAIENAQRKVEGRNFDIRKNLLEYDNVANDQRKVIYQQRDELMNTEDISELIASLREEVLNATIDQYIPPQSIEEQWDIPGLEAALKEHFDLDLPIQQWLDEDGELHEETLRQRILDAMVASWKEKEDQIGSEQMRRLEKEVMLFTLDSYWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKREAFEMFQRMLASIKQEVVEILSKLQIQEPPSIQEPAVDPNAFEFRHEEFTGLDEPEAGVPAPGAGEEAPAQQPFVREGRKVGRNDPCPCGSGKKYKHCHGKLQ
>NZ_AP012978.1|WP_043107111.1|483812_484727_+|M23-family-metallopeptidase
MNIILLSKKKGSIDICVPSAVRWLVPGVALFSALLVWAGYELGSWHTEKTRSASAVAQLRQLVDREREQLEIARSEQRAHLDALALRVARLQAHLMRLDALGERLVGLGKLDDKEFDFSAEPAQGGLEGEQAASPDTNDILDTMQRIERLLADREDKLRMLEEQLANRELIRETSLSGRPIDNGWISSVFGRRTDPITGKKAWHHGLDFAGKEGEPVRAVAAGVVVRANHEKGYGNVVEIRHPDGYTTIYGHNKKNLVSKGDVVAKGQVIALLGNTGRSTGPHVHFEVRRQGRKVDPKRYIRAP
>NZ_AP012978.1|WP_043107110.1|483262_483715_-|DUF721-domain-containing-protein
MRAKPRRIAVILQQQPQLAGLIARSRQHRELLAQVRDALPSDLATHCTSATLNGSILHLQVDSPVWGARLRYHTPSLLSRLRARHPGLASIRVRPRVATPARASRTSRRRFRLHRSPQAAEHLERAARSISDEKLCHALRRLAKTLSEKE
>NZ_AP012978.1|WP_043107108.1|482344_483256_+|UDP-3-O-acyl-N-acetylglucosamine-deacetylase
MIRQRTLKNVIRATGVGLHTGEKVYLTLRPAAPDTGIVFQRVDLPQPVEIPARAEYVGDTRLSTTLERDGVRISTVEHLLSAFAGLGVDNAYVDVSAPEVPIMDGSAGPFVFLIQSAGVEEQNAPKRYIRILEPVEVRDGDKLARFEPFEGFKVRFAIDFDHPAIDGRACEAEMDFSSTSFVKEVSRARTFGFLRDIETLRENGLALGGSMENAIVVDDFRVLNEDGLRYQDEFVKHKILDAIGDLYLLGHSLIGAFTGYKSGHALNNRLLKALMAREGAWEEVTFENEDTAPISYMKPIQVS
>NZ_AP012978.1|WP_043107107.1|480985_482176_+|cell-division-protein-FtsZ
MFELMDVDSQSAVIKVIGVGGGGGNAVNHMLRSNIEGVEFICANTDAQALNSTEVRTALQLGSNVTRGLGAGANPERGYEAAMEDRDRIAEALDGADMVFITAGMGGGTGTGAAPVVAEVAKELGILTVAVVTKPFAFEGPKRMKIAEAGIKALTEHVDSLITIPNEKLVSVLGKGVTLVDAFKAANDVLLNAVQGIAELITKPGLINVDFADVRTVMSEMGVAMMGTGRASGEDRAREAAELAIRSPLLEDINLSGARGLLVNITAGMGMSLGEFDEVGSTIREFARDDATVVVGTVLDPDMVDEIRVTVVATGLGAEEAVAEPAPQPVDLQPVRVANGEPMVEPVASSPDDYAGLDVPTAVRRQAESRKGYVDAATRQDMEYLDIPAFLRRQAD
>NZ_AP012978.1|WP_043107106.1|479685_480921_+|cell-division-protein-FtsA
MVKKTDRNIIVGLDIGTSKVVAIVGEVKDDNSIEIIGLGSHPSRGLKKGVVVNIESTVQSIQRAVEEAELMASVEIDAVYAGIAGSHVSSLNSHGIVAIKDGEVTHADVERVIDAARAVPIPADQKILHILPQEFIIDNQEGIHDPVGMSGVRLEARVHMVTGSVSAAQNIIKCVRRCGLEVEDLILEQLASSYSVLEEDEKDLGVCLVDIGGGTTDIAVFTGGAIRHTGVIPIAGDQVTNDIAVALRTPTQHAEEIKLKYACALTQLASPDETIEVPSIGDRPPRRLSRQTLAEVVEPRYEELLTLIQAELRRSGFEDLVAGGVVMTGGSSKMEGVIDLAEEVFHMPVRLGIPQYVTGLDDVIRNPIHATGVGLLLFGHRNRASRVPEMAVGGGFKSVWNRMKSWFQGNF
>NZ_AP012978.1|WP_070104708.1|478906_479686_+|FtsQ-type-POTRA-domain-containing-protein
MAARRPGKQAAAPRGRSGISLGLLSALLLVALVFAGWQALTRPDRLPVRRIEITGEFTHLRTADIERRVAQVLDGGFLDLDMRQVRAAVMALPWVDQVSVRRVWPDTLRMHVVEQVPLARWNEDALVNLRGQVFRPDPLPALDGLPRLRGEDGMAPEVVAFYLRLHAGGLPEGLEIAELARNQRGEWRVVFANRLELMLGREDLGARLAAFSRIYPQLAAHMGRRPRRIDMRYEHGFAVQWQPADEAQASLAGGGTGEI
>NZ_AP012978.1|WP_043107105.1|477984_478917_+|D-alanine--D-alanine-ligase
MSLCAEDFGKVAVLMGGWSAEREVSLVSGAAVLEGLRARGVDAHGIDMGRDVLEVLRAGGFDRVFNVVHGRGGEDGELQGLLEVAGIPCTGTGVLGSALAMDKYRSKLVWAGMGLPTPGFVLVEDEADLEHAARLGFPLMVKAALEGSSIGVYRVEDAVALREAWEKAAACDSHVMAEVCIEGEEFTCAILDGEALPMIRLETPHSFYDYEAKYRADDTRYLIPCGLSAEEEAAAQALCQRAFAAVGAAGWGRVDLMRDAGGRLWLIEVNTVPGMTDHSLVPMAARAAGIDFPELVWRILAQTLEVEHGG
>NZ_AP012978.1|WP_043107104.1|477091_477988_+|UDP-N-acetylmuramate-dehydrogenase
MMAARQNTPWRGELRFDEPLARHTSWRVGGAARRFYRPADAEDLAAFLRELPADEPLLWLGLGSNLLVRDGGFAGTVIALKGRLDTIDIDGDVLHAGAGASCARAARQAARAGLTGAAFLAGIPGTLGGALAMNAGAFGGEIWPVVRAVRTVDRAGILRRRLPADYRVGYREVTGPAGEWFVGVELQLRSGDVAAEQAAIRGLLERRAATQPTGLPSAGSTFRNPPGDHAARLIEAAGLKGYRIGGAEVSPKHANFLINTGEATAADIEALIAHVRDEVERRFGVRLQTEVHIVGEPT
>NZ_AP012978.1|WP_043107103.1|475512_476940_+|UDP-N-acetylmuramate--L-alanine-ligase
MSRLPDTPRYAAETMGRMRRLHFVGIGGAGMNGIAQVMLNLGYEISGSDIRTNAATERLAEQGARIFIGHAAEQVAGVDAVVISSAVTEDNPEVVAAREHRIPVVPRAEMLAEIMRFRYGIAVAGTHGKTTTTSLIASLLIDGGMDPTYVIGGRLNAAGSHAHLGEGEFLVAEADESDASFLYLQPMLAVVTNVDEDHMSTYGGDFDRLRATFLEFLHHLPFYGVAVICIDDVNARELLPDVTRRVITYGFDAGAEVRGSELRQQGGTTRFTAHLPSGERFAVQLAMPGRHNALNALAAIAVGHELGLAPESMQRTLAQFQGIGRRFQLRECRLADGGEVLLVDDYGHHPRELEATLAAVRAGWPERRLVLAFQPHRYSRTRDAFDDFARVLSTSDVLILSEVYAAGEAPIAGADGRALSRAIRARGQVDPIFIEDIAELPQVLAGVVREGDIVLTMGAGSIGQVAVQLEEELCR
>NZ_AP012978.1|WP_043107113.1|487776_488967_+|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ
MITDNPLPVSGFRLAVAEAGIRYQGRPDLCLMELPEGSATAAVFTRNRFCAAPVIVAREHLAKDAPRYLLINAGNANAGTGDEGLRAARETCRAVAAMAGCAMSQVLPFSTGVIGEDLPLTPFQHAMPGLVQDLREDAWGEAARAIMTTDTRPKCWSTVVELSAGPVVITGIAKGSGMIRPDMATMLAYVATDARIARDDLQAMLETAVRGSFNSITVDGDTSTNDACVLVATGASGVAPAGDDRVRFEQALGAVCFALAREIVRDGEGATRTVDIEVSGARSAEDARAVAYTVAESPLVKTALFAGDPNWGRILAAVGRAGVALDIAAVRIWLGDVLIVSNGGRDPGYREEDGARVMAEKEYAIRIDLGRGTAQARVMTCDLSYDYVKINAEYRS
>NZ_AP012978.1|WP_043107116.1|488966_489902_+|Nudix-family-hydrolase
MTETVHVAAGALIDDRGRVLLTRRHDHAHQGGLWEFPGGKCEAGETPQAALVRELREELGVEVTACRLLIRVAHDYGDRRVLLHVFRVEAWEGKPRGLEGQPLEWVEPAALEGYPMPAADRPVVTALRLPDTCLITRPEGDAPESVLAHLERGLAAGVRLVQFRVFGVGEEGRWRLFDQVRARCREADALLLCNSAMGIDGVEADGLHLSARDLHRLHERPAGLRWLAASCHSPDDLRRAEALGADFALLSPVLPTPSHPDAAPLGWTDFAQAVETVNLPVYALGGMRPDLCEIAWHHGGQGIAGIRGIVP
>NZ_AP012978.1|WP_043107118.1|489898_490285_+|hypothetical-protein
MKLNRYLFFYIILGLGLVTSWTLVGKRARIAPDLGVRIMSVDETCRPLLAPCGAYAQHFALVLGPVGDGHTLRLIGEQLPSDVRLSVLQYDDKAQQLAPPPVQDTGRRHLAARARPRGRARARQPGVW
>NZ_AP012978.1|WP_081999774.1|490432_490612_-|DNA-gyrase-inhibitor-YacG
MKTPARKTVACPTCRKPVLWSPASRWRPFCSERCRLIDLGEWLSEEKRIPGDPAYAPEN
>NZ_AP012978.1|WP_043107119.1|490608_491376_-|cell-division-protein-ZapD
MSEHIIFEQPLNEKCRTMLRLAHLFEQFDYHMPCSTPWHARAALRALLDISVILARADIKSELIKEMERYHGSLSRMADLPDVDHNRLQHILQNLRDNQQALQAVRGQLGASLRSSDFLNSVLQRSAIPGGGFDFDLPQLHYWLALPHAERLLQFDDWRNEVAPVHEAVDLLLGLIRHSTTFQPQQASAGFYQQTLPGNAATQMIRVRLPEEARLYAEISGGKHRFSIRFMDSSDWEHPVQTVRNITFELNICII
>NZ_AP012978.1|WP_043107120.1|491475_492078_-|dephospho-CoA-kinase
MLKVALTGGIASGKSLASEHFASLGVPVIDADQVARELVEPGRPALAAIVEHFGPAILTADGTLDRRALRQRIFADAEARRALEAILHPAIRQRMQELAEAAHGPYLVQVIPLLAESDLDWDQDRVLLIDCPETLQRQRLMARDGCSAEQAEAILASQATREQRRCIADDILVNDGDTRTLQQGIETLHARYLEAGSSHD
>NZ_AP012978.1|WP_171816164.1|492082_492814_-|prepilin-peptidase
MNPPSRRSPQRWFGLDYLIHPGSHCPACGHAISPWENIPLLGWLLLRGRCNQCGVRISARYPVIEGLTALITMGVVMHFGMHWHTLAIALLAWGLIVLAMIDIDEQLLPDQITLPLLWLGPLINLPGRFVPLEDAVIGAVAGYLSLWFVFQLFRLLTGKEGMGYGDFKLLALFGVWLGWQMLPQIILLSSVIGALIGMALIALRRHDRGKPIPFGPYLILGGLVALFWGEQINQSYLHLTGLD
>NZ_AP012978.1|WP_043109082.1|492983_494216_-|type-II-secretion-system-F-family-protein
MAKATAAVKQKPQVFVWEGSDRKGKRLKGETRTSSITMVKAELRRQGITPLKVRKKATGLFTHRKQKIAPKDIAVFARQLATMMASGVPMVQAIEIVARGHSNPAMQDLLLSIKNDVEGGSTLTDALRKHPLYFDDLFCNLVHAGEQAGVLETLLDKIATYKEKTESLKGKIKKALFYPTAVVVMAIVITAIIMIFVIPQFKSLFVGFGADLPAFTQLVVSLSDFVAAWWWAILLSIIEFFSVMAFVWKRSPRLREILDTLLLKLPVLGNIMHKAALARFCRTTATMFAAGVPLVEALGSVAGATGNRVYEKAVLAMRDDVATGQSLQLTMKQQGLFPHMVIQMVAIGEESGALDEMLTKVADFYEEEVDNAIDALSSLLEPMIMAILGTLIGGLVIAMYLPIFQMGSVF
>NZ_AP012978.1|WP_081999775.1|494218_495391_-|type-IV-A-pilus-assembly-ATPase-PilB
MRGGSPVVRYVNKILLDAINGNASDIHFGPYEKDFRVRFRQDGILHDVAHPPVNLAPRLVARLKVMARLNTAERRVPQDGRIKLALSRNRSIDFRVNTCPTLYGEKVVLRILDSSAARVGVDALGFEKAQKEAFLNAIKKPYGMILVTGPTGSGKTVTLYTALNLLNKPEVNISTAEDPVEIQVPGINQVNVNPKTGLTFAEALRAFLRQDPDIVMVGEIRDLETAEIAIKAAQTGHLVLSTLHTNDAPQTLTRLANMGIPPFNIASSVHLIMAQRLARRLCEHCKEPDDLAREALLKEGFSEADLEGDWQVYKAVGCDKCTMGYKGRVGLFEVMPISEEMERLIMNNADAIQLRDQANAEGIEDLRASGLRKVKAGIISLEELNRVTKD
>NZ_AP012978.1|WP_148307615.1|495415_496635_-|IS3-family-transposase
MDTSKRYSPEVRERAVRMVFDHQGEHDSQWAAMTSIAAKIGCTPETLRKWVRQAERDQGLREGLTTSERERLKALERENRELRRANEILKTASAFFCPGGARPQTEEMIAYIDDHRDRYGVEPICAVLPIAPSTYYEHKAREADPQRLPRRLQRDRALSDEIRRIWEENFQVYGARKVWRQLNREGIEVARCTVERLMRVMGLRGVVRGRRCRTTIGDTTAERPLDRVKRQFTATRPNQLWVADITYVATWTGFVYVAFVVDVYARRIVGWRVSRSLKTDLVLDALEQALWSRQDTEGLVHHSDRGCQYLSVRYTERLAGAGIDASVGSRGDSYDNALAETINGLYKAEVIYRRGPWKHREAVEYATLEWVDWFNHRRLLEPIGNVPPAELEAAYYRQQKESAKAA

Crispr_ID: NZ_AP012978_2

• CRISPR_ID: NZ_AP012978_2
• CRISPR_location: 729445-729582
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP012978_2

Consensus_repeat	Method
CATTGGCGAGCAGAAGCTCGAGTTCGGCTACGTTCACGAAAAGCGC	CRISPRCasFinder

spacers of NZ_AP012978_2

>2.1|729491|46|NZ_AP012978|CRISPRCasFinder
CTGACCGTTTCCATGTCTGGTCCGGCGAGGGGCGGGTCAGCTATGG

CRISPR arrays and Neighbor proteins around NZ_AP012978_2

CRISPR arrays

The CRISPR arrays of NZ_AP012978_2

>merge|NZ_AP012978|2|729445-729582|CRISPRCasFinder
CATTGGCGAGCAGAAGCTCGAGTTCGGCTACGTTCACGAAAAGCGCCTGACCGTTTCCATGTCTGGTCCGGCGAGGGGCGGGTCAGCTATGGCATTGGCGAGCAGAAGCTCGAGTTCGGCTACGTTCACGAAAAGCGC

>NZ_AP012978|2|2|729445-729582|CRISPRCasFinder
CATTGGCGAGCAGAAGCTCGAGTTCGGCTACGTTCACGAAAAGCGC	CTGACCGTTTCCATGTCTGGTCCGGCGAGGGGCGGGTCAGCTATGG
CATTGGCGAGCAGAAGCTCGAGTTCGGCTACGTTCACGAAAAGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_043107334.1|730869_733071_+|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl|CDD|273391
NZ_AP012978.1|WP_043107325.1|718034_719291_+|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|379337
NZ_AP012978.1|WP_043107329.1|720486_721269_+|WecB/TagA/CpsF-family-glycosyltransferase	unknown	unknown	gnl|CDD|119439
NZ_AP012978.1|WP_043107323.1|717360_718056_+|phosphotransferase	unknown	unknown	unknown
NZ_AP012978.1|WP_043107344.1|738532_738922_-|DUF302-domain-containing-protein	unknown	unknown	gnl|CDD|269820
NZ_AP012978.1|WP_148307629.1|727324_727666_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_052199260.1|727653_728682_+|O-antigen-ligase-family-protein	unknown	unknown	gnl|CDD|377422
NZ_AP012978.1|WP_148307631.1|737724_738540_-|hypothetical-protein	unknown	unknown	gnl|CDD|179854
NZ_AP012978.1|WP_052199256.1|715596_715980_-|IS110-family-transposase	unknown	unknown	gnl|CDD|376773
NZ_AP012978.1|WP_148307632.1|739059_739932_+|hypothetical-protein	unknown	unknown	gnl|CDD|370723
NZ_AP012978.1|WP_052199258.1|723477_724473_-|GDP-L-fucose-synthase	unknown	unknown	gnl|CDD|187550
NZ_AP012978.1|WP_043107336.1|733085_733805_+|capsular-biosynthesis-protein	unknown	unknown	gnl|CDD|226870
NZ_AP012978.1|WP_043107337.1|733804_734470_+|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NZ_AP012978.1|WP_171816170.1|721560_722739_-|undecaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl|CDD|131433
NZ_AP012978.1|WP_148307630.1|729678_730224_+|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|313331
NZ_AP012978.1|WP_043107342.1|735532_737635_+|elongation-factor-G	unknown	unknown	gnl|CDD|234569
NZ_AP012978.1|WP_043107328.1|719287_720490_+|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_AP012978.1|WP_043107340.1|734755_735202_+|transposase	unknown	unknown	gnl|CDD|224854
NZ_AP012978.1|WP_043107331.1|726411_726963_+|hypothetical-protein	unknown	unknown	gnl|CDD|371316
NZ_AP012978.1|WP_043109171.1|730278_730806_+|polysaccharide-biosynthesis/export-family-protein	unknown	unknown	gnl|CDD|224512

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_043107340.1|734755_735202_+|transposase	gnl|CDD|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.26277e-18
NZ_AP012978.1|WP_043107325.1|718034_719291_+|glycosyltransferase-family-4-protein	gnl|CDD|379337	pfam13692, Glyco_trans_1_4, Glycosyl transferases group 1.	3.23003e-24
NZ_AP012978.1|WP_043107329.1|720486_721269_+|WecB/TagA/CpsF-family-glycosyltransferase	gnl|CDD|119439	cd06533, Glyco_transf_WecG_TagA, The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common antigen (eca) synthesis. B. subtilis TagA plays a key role in the Wall Teichoic Acid (WTA) biosynthetic pathway, catalyzing the transfer of N-acetylmannosamine to the C4 hydroxyl of a membrane-anchored N-acetylglucosaminyl diphospholipid to make ManNAc-beta-(1,4)-GlcNAc-pp-undecaprenyl. This is the first committed step in this pathway. Also included in this group is Xanthomonas campestris pv. campestris GumM, a glycosyltransferase participating in the biosynthesis of the exopolysaccharide xanthan.	3.72285e-71
NZ_AP012978.1|WP_043107334.1|730869_733071_+|polysaccharide-biosynthesis-tyrosine-autokinase	gnl|CDD|273391	TIGR01005, Putative_tyrosine-protein_kinase_EpsB, exopolysaccharide transport protein family. The model describes the exopolysaccharide transport protein family in bacteria. The transport protein is part of a large genetic locus which is associated with exopolysaccharide (EPS) biosynthesis. Detailed molecular characterization and gene fusion analysis revealed atleast seven gene products are involved in the overall regulation, which among other things, include exopolysaccharide biosynthesis, property of conferring virulence and exopolysaccharide export. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.18842e-81
NZ_AP012978.1|WP_043107344.1|738532_738922_-|DUF302-domain-containing-protein	gnl|CDD|269820	cd14797, DUF302, Uncharacterized domain family DUF302. These domains are mostly found in bacterial single-domain proteins and have been shown to form homodimers; they may also bind zinc. Also characterized as COG3439.	2.15982e-38
NZ_AP012978.1|WP_148307631.1|737724_738540_-|hypothetical-protein	gnl|CDD|179854	PRK04457, PRK04457, polyamine aminopropyltransferase.	9.22188e-27
NZ_AP012978.1|WP_052199260.1|727653_728682_+|O-antigen-ligase-family-protein	gnl|CDD|377422	pfam04932, Wzy_C, O-Antigen ligase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.	2.46253e-09
NZ_AP012978.1|WP_052199256.1|715596_715980_-|IS110-family-transposase	gnl|CDD|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	4.22938e-14
NZ_AP012978.1|WP_148307632.1|739059_739932_+|hypothetical-protein	gnl|CDD|370723	pfam09849, DUF2076, Uncharacterized protein conserved in bacteria (DUF2076). This domain, found in various hypothetical prokaryotic proteins, has no known function. The domain, however, is found in various periplasmic ligand-binding sensor proteins.	0.00608025
NZ_AP012978.1|WP_052199258.1|723477_724473_-|GDP-L-fucose-synthase	gnl|CDD|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NZ_AP012978.1|WP_043107336.1|733085_733805_+|capsular-biosynthesis-protein	gnl|CDD|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	3.63809e-60
NZ_AP012978.1|WP_043107337.1|733804_734470_+|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.000733244
NZ_AP012978.1|WP_171816170.1|721560_722739_-|undecaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl|CDD|131433	TIGR02380, ECA_wecA, undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase. Members of this family are the WecA enzyme of enterobacterial common antigen biosynthesis, undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase. This family represents one narrow clade, and closely related sequences outside this clade may represent enzymes that catalyze the same specific reaction, but in the context of different pathways. A His-rich motif in a cytosolic loop of this integral membrane protein, shown critical to enzymatic activity for WecA is variously present or absent in the clade that includes Bacillus subtilis TagO teichoic acid biosynthesis enzyme, which may catalyze the same reaction as WecA. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	7.119e-94
NZ_AP012978.1|WP_043107328.1|719287_720490_+|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	3.66624e-50
NZ_AP012978.1|WP_043107342.1|735532_737635_+|elongation-factor-G	gnl|CDD|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	0
NZ_AP012978.1|WP_148307630.1|729678_730224_+|outer-membrane-beta-barrel-protein	gnl|CDD|313331	pfam10082, BBP2_2, Putative beta-barrel porin 2. This domain is a putative beta-barrel porin type 2.	3.14337e-13
NZ_AP012978.1|WP_043107331.1|726411_726963_+|hypothetical-protein	gnl|CDD|371316	pfam10961, SelK_SelG, Selenoprotein SelK_SelG. This entry inclues a group of eukaryotic selenoproteins, such as SelK and SelG. SelK seems to play an important role in protecting cells from endoplasmic reticulum stress induced apoptosis. SelG may be involved in regulating the redox state of the cell.	0.00538751
NZ_AP012978.1|WP_043109171.1|730278_730806_+|polysaccharide-biosynthesis/export-family-protein	gnl|CDD|224512	COG1596, Wza, Periplasmic protein involved in polysaccharide export, contains SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis].	1.44354e-38

Protein sequences

>NZ_AP012978.1|WP_052199260.1|727653_728682_+|O-antigen-ligase-family-protein
MFWLKSLSCLLVFVLTLALVNSRARLRRLMWVLVFSGAFQAVYGSLMVMSGLEWGFFFHKDTGQGVATGTFINRNHLAGYLELCLALGIGLLLAGLEEERVLGWRQRLRHWVRTLLGPKLRLRVLLAAMVVGLVMTHSRMGNSAFFTSLLVTGGLWLVATGRRSWSGPLLLLGSLLLIDTFIVGHWFGVERVMQRIEQTRIETEQRRYVAEDTLAPVRDFWRTGSGAGSFYTVYPAYRDGIVQGFYDHAHNDYLELAVETGLPGSALLLFIALPSWWMGMRAMWRRRRRLYRGAGFAVIMAGIAFAMHSSVDFNLQIPSNAILFVVLLALGWVAAYQRPSEN
>NZ_AP012978.1|WP_148307629.1|727324_727666_+|hypothetical-protein
MGFLALLLWLPLPVGSNRVWAVVLMYTLLSLLAAWWLGLWLRHRVEPGPALMQARWVLLVFVLWLVWLALQRLPLPPGGLSWLSPRAWQAWREVDPQGTAPVSLEPWAGGCSG
>NZ_AP012978.1|WP_043107331.1|726411_726963_+|hypothetical-protein
MKNKIGVVLALCLMGVAMPGMVLADEDKGGQAAEQAQSAEAMLQALLDQGMPVEKALKKVLEKYPEAAPNLIAKAVQAALAQKGEADKTIEKIVKVAQETLGEGGEQAAIAQGLLLAGVDPEPYLEATAAGKKDKDKKKKKKKKDDDNGNDDNGNDGNTDTGTGGGLPGGGGGGGGGGGVSPS
>NZ_AP012978.1|WP_052199258.1|723477_724473_-|GDP-L-fucose-synthase
MAFLDDAGARVYVAGHRGMVGSAILRALKRAGFANLLTRTSAELDLRRQAEVEDFFAQERPDYAFLAAARVGGILANDSYPADFLYDNLAIEANIIHAAHRTGVKKLLFLGSTCIYPKLAPQPLKEEYLLTGPLEPTNEWYAVAKIAGIKLCQAYRKQHGDDFISAMPTNLYGPEDNFDLEKSHVVPAMMRKMHEARERGEAEVPLWGTGKPLREFLHVDDLAEALLFLMQHYSDAEHVNVGVGQDLSIRELAETIARVVGYQGELAFDPTKPDGTPRKLVDTTKINALGWHPRIGLEEGLRDTYRWYLANRDRLRGQDRQATAKEPLINS
>NZ_AP012978.1|WP_171816170.1|721560_722739_-|undecaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MLRKIAFRIDLLDRPDSRKQHQGAIPLVGGLGIYAGFVLTGLLLGIPLYDYAALIVGGLILVAVGLVDDLHELPPQARFVAQAIAALLMIYWGGVELTDLGYLLPGIDHPVKLAWLCVPFTVFATIGVINALNMVDGVDGLAGSVVLNALLAWLSHDLADVSVLLLLASAVMAFLGFNWRFKLDKKPLMFLGDAGSLLLGFVLTWFMIKLSQGEHRAMAPTTAPWLVAIPLIDTIVMMVRRIRKGRSPFTADREHFHHVLQYAGFNRRETVFIILGASVVFSAIGIAGELQRVPEPVMLAAFLAVFATYYALIMRSWRMMRFLKRSICRRHKHDRRQLQDRRQQQIPWVGPERRQLADRRQTLDRRTSGDTAPSSPTPSAPQSTGKKVGALR
>NZ_AP012978.1|WP_043107329.1|720486_721269_+|WecB/TagA/CpsF-family-glycosyltransferase
MKQRREDICGYRVGTSGVEDTVAEVVDWIWSGDKRAECRWLACLNPHSYAESLKDERFAAALRRADWLVPDGAGIVLASRMLGGRIRERVTGSDIFKGVLDSLNEVGGYRVFFLGSTEQTLAEIRARMARDYPRVEVAGTYSPPFKLEYTEQELDEMVEAINRAAPDVLWVGMTAPKQEKWIFGQQERLNVRFAAAIGAVFDFYTGRVKRPHPMFQRMGLEWLPRLVQQPRRLWRRMGVSAPVFLAHVMRQKVVLQKRTS
>NZ_AP012978.1|WP_043107328.1|719287_720490_+|glycosyltransferase-family-4-protein
MKILLTHNFYGSSAPSGETSVVESEQRMLVSRGHEVATFFRHSDEIRGQGAWGAIKGALATPWNPFSTRAMRRALEESGSDVVHVHNTFPLISPSIFPAIGSRAARVLTLHNYRLFCPAAIPMRAGRVCTRCIDEARVGAALRHGCYRDSRLATAPLAANVALHRRLGTWQKHVDAFITLTEFQRQVMIDAGLPAEKVHVKPNFYPGDPEVIPWESRRETVVFVGRLSVEKGVETLLQAWRQWGTDAPELRIVGDGPLAGELRRLGRGLPVCFLGQLPPEKAQEEIGRARLLVLPSECFEGFPMVIGEAFALGTPAAVSRIGPLPEIVRMGEAGVVFAPGDPDALLEAVCNAWASLDRLRRVGERARVTFEEKYTESINYRLLMEIYETAMEVNKKRAKG
>NZ_AP012978.1|WP_043107325.1|718034_719291_+|glycosyltransferase-family-4-protein
MAKDRRLKVLVSAYTCSPYRGSEFAVGWGFVQAMAKRHDLWVIVEEEKCRADIERYLNEHPKALPNVRFFFLRKQRNRRLRRLWPPSYYWYYRRWHSQAFELAKKLHEEVCFDLAHQLTMVGFREPGYLWRMEIPFVWGPVGGMGRFPWRFLPEVGRYGALYYLGYNLYNLAQMRFMRRPRLAARRAGNEGLLPATSENREGAMCHWGVAGQVMPEVGLPRKPVEVVNARAPDEPLRIIWTGLHIPRKALPLGLRALARLPRAIPWELHVLGKGPRTTAWKRLASRLGIQDRCRFHGWREREAVLSLMAQGHLLLITSLRDLTSTVTVEALALGLPIVCLDHCGFAEVVNEDCGIKVPVTSLREVVSGIARALETLADDEPYRRRLAEGALVRAHDYDWDAKARVLEAVYRAKAGVDR
>NZ_AP012978.1|WP_043107323.1|717360_718056_+|phosphotransferase
MAALSREADALRHLENSEVSDQVPRLMDFVQSGGQAAIHQSYRRRRPLDESAMHREVLAFLGRLADIDRKERRLADVMQQQAVVAGIHWCEARGMAGTVLRRLRHLCEEDIRVTGHRSHGDFAPWNCAWTDAGLFVFDWEESREWELLLADAFYYAVAPSLHIRSQKERLEVLSERALALHGKAADHAGIEPGNNEIHWALWLLRQLGLQPKPLYGDLLGELERSWQKTGA
>NZ_AP012978.1|WP_052199256.1|715596_715980_-|IS110-family-transposase
MRVQAIEGIGPLTAAALVTAFQRGSFRSSDAFIMDVRVHDSGQMRGRRKLTKKGNAELRRLLYLAAMRACRTPAWRDFYQRYLDRGLAPVQALVQALVILGRKLARVAFAILRNETEYRPRNRCMQT
>NZ_AP012978.1|WP_148307630.1|729678_730224_+|outer-membrane-beta-barrel-protein
MTFDLDLQKINYDVAALDSTELRGLVGVRWEATFQTAGFAKAGWQKKNMSSAGLSDASGASWELGVDWKPLSYSSFQLSTSRDFGESDGVGSYQDTRSLGLAWNHDWTDVLGTRLSLDKSRIEYGGSTRRDRNRSFGIDVEYRAPPWLLFGATISHSRRDSNQAGLDYKDNQFGVQVGINM
>NZ_AP012978.1|WP_043109171.1|730278_730806_+|polysaccharide-biosynthesis/export-family-protein
MEGGLVVLLSCLLGNMALAAQALDNYRLGAGDKIRIQVYGEKDLSVETLVDDSGTISYPFLGEIQVKGSTLREVEQRITEGLRGDYLVNPEVTVSIVEYRHFYVNGWVKSPGSFPFQPGMTVRKAISLAGGFAERANKRALTVVHGDDAFGKPQQIHLDDQLHPGDIISVGRSFF
>NZ_AP012978.1|WP_043107334.1|730869_733071_+|polysaccharide-biosynthesis-tyrosine-autokinase
MNAQDISREPVREEFDDETVDLREYWRIIHSHKWSIIGIALLFVLVVFKQRPVYQATASLLIEPESTRIVQIEDVYAVSGDDAYYRTQVEILKSRALAARVIDKLSLADNPEFLPQKDSGWSFRLNWREWFAAWLPAADEGAPDPEAEALAAREALIGDFLDRLKVAPVRNTRFVRISFEAHDPALAALIANTLADTYIESDLDARLEMTKKATAWLASRLEELKKKLRVSEQALQAYREKEKLIDSGGVGTLTAEQLQDLRQNLVVAEQERIRAQAAVSQVRAAKGDPDKLSSIPAVLNDPVVSSLKGAEVDAERRLKILAKRYGAKHPKMAAARADLQEARAAVRKRVSSVIASLVKEYQVALTNERAIRASLENAKDEMQSIHRKSYQLNVLEREVDSNRQLYEMFLRRLKETSQAGDLQKANARIADPAAVPVVPVKPKKRQIVSIAGVLGLLFGIGLAFLLERLDNTFKRASDVEERLGLPLLGAVLHLKLGKGETPLDYARSHPQSRFAESIRTVRTSVLLSGLDEPYKVIVITSSVPGDGKSTLAMNLADSLGEMHKVLLIDADLRRPTVATTWGLDRKAKGLSEFLSQSANASECVHQLDERNVYVMPSGVVPPNPLELLSSRRFKEALDTLGRTFDHIIIDSAPALAVSDALVLSRNASGVIYVIKADSTPYPAAQEGIKRLRHYKAHLIGAVFNDVSQKKKKGYGYYDGDGGGYYASYGYTQD
>NZ_AP012978.1|WP_043107336.1|733085_733805_+|capsular-biosynthesis-protein
MIDLHCHLLPGIDDGAKDLDEALALARVAVDAGICHAVMTPHVHPGRYDNHRDGIAAACEDFQQALDAAGIALRVSPGAEVRVSDQVVLQARQGVLPTIGEWEGRPVVLLEFPHSHIPPGSEKLTAFLLRQGYQPMIAHPERNKDVIRRFEKIHPFFEQGCLLQVTAAAVTGGFGSQALKRAWQLLERGWVTVLASDAHNLHARPPDMRPGFKAVCERLDETTAWSLVRDNPARICGLA
>NZ_AP012978.1|WP_043107337.1|733804_734470_+|hypothetical-protein
MAARGPGLRIAASGLMVALLVVAVGAFPRGVADVYAYFVQAHLDTWAERRHLPKEQEWQRARELVRAALGWTPEDPRLLQQAGGLYEWGALIAPRAESRGAQALQYYRDSLARRPAWPYAWADLAVAKARFGQIDAEFQQAFARALETGPWEPEVQLNIARAGFLAFKRLSRANRAALARTIQRMSSRQLPELVRIAEESDSLWIVCTLRGDQPVVQRACT
>NZ_AP012978.1|WP_043107340.1|734755_735202_+|transposase
MVPVYHGKDLRKGRVSIPGQIYHVTTVTRAREPVFQDLNSARRVIQVLMEIQSHELADTLAFVVMPDHVHWLLQLGERRPLSCVIASMKSISARRIGRGKIWLAGFHDHALRRDEDLRQVARYIVANPLRAGLVDDIGHYPHWDAIWL
>NZ_AP012978.1|WP_043107342.1|735532_737635_+|elongation-factor-G
MTDLTLYRNIALYRNIGIFAHVDAGKTTTTERILNLTGKTHKIGEVHDGEATTDFMDQERERGITIQSAATTCFWKDHRLNIIDTPGHVDFTIEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYANESEVARIIFVNKLDRMGADFYRVVKQVEDVLGANPLVMTLPIGIEDEFVGVVDLLTRKAWIWDDSGDPHKYHIEDVPADMTDKVEEFREKLIETAVEQDDDLMEAYLEGEEPSIEDVKRCIRKGTINLDFFPTYCGSAFKNKGIQLVLDAVVDYLPNPTEVKPQPEVDLEGNETGEYAIVDPDRPLRALAFKIMDDRFGALTFTRIYSGRLKKGDTVLNTYTGKTERIGRIVEMHANERKELDSAQAGDIIALVGLKNTQTGHTLADPNNPATLEPMVFPDPVISIAIKPKDKGSTEKLGVALNKMMQEDPSFRVETDEDSGETIIKGMGELHLDIKVDILRRTHGVDVEMGKPQVAYRETITKRVEDSYTHKKQTGGSGQFAKIDYVIEPGEPNSGFQFESTVTGGNVPREFWPAVEKGFAVSMQEGPLAGFPLLDVKVTLVDGGFHPVDSSAIAYEIAAKGAYRQSVPKAGPQLLEPIMKVDVFTPEDHVGDVIGDLNRRRGMIQGQESGPTGVRVKAECPLSEMFGYIGDLRTMTSGRGQFSMEFSHYAPCPANVAEEVIKETKARKEAG
>NZ_AP012978.1|WP_148307631.1|737724_738540_-|hypothetical-protein
MAETTDKPHPLGRIVARREDACGPVEVRELGQHRFLTFGNVVEQSCCNTAQPWRLEHVYTQAMMLGLLLRPDPGSALILGLGGGSLVRALRHAAPDLRLAAVESRQAVIELAIEWFGVDPGDPQLRLHCADAADFVAGTQERFDLIFADLYLAEGVNPVQTRLDFLEHTRERLARHGLLLLNAWCSEFRDARETHQALDAVFGEFRLALHVQGGNSIIFAFRDHLPVVDRNRLFSSAQAMGLRLDIPLQRLARTLWRQNAQALRSGRYRPG
>NZ_AP012978.1|WP_043107344.1|738532_738922_-|DUF302-domain-containing-protein
MYEFNLTLDLPFEQALEKVREALMSEHLGIVSEVDVQAIFKAKMDKDIPPYRILGACNPKLADRVLSVEPNAGTLLPCNLVLRDAGDDKTVVSFMDPVAVLGLSESAEVRAVAEEARDKLQRVVAGLGG
>NZ_AP012978.1|WP_148307632.1|739059_739932_+|hypothetical-protein
MKQSIKSLSAAILLGLASGAGQVLAQGYPQGGYSAPPQPPAVPYGYAQPGYGDYGYGQYPGYGYQAPPSAGAYAYPGAQGYYPPAYGSSMPYGGFPRGFGKKRWDDWDLFGGDNPLQNPLDHEGYWAHPRFQPWRSGPFAHDKWRDHPMKQMPWGNFPGWGDGFFGGYGPDRWKGVTPWGNDVPFKWIDPSDPEESIANMWEDAINTPYNMGRMPPGWTAPQISVPNPIDVENEFERNFRNAPTEFRNMWGEEGAGFGSAGKPKAKKAEKKPQQNPQEKPAAAKPAPADR

Crispr_ID: NZ_AP012978_3

• CRISPR_ID: NZ_AP012978_3
• CRISPR_location: 734482-734742
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_AP012978_3

Consensus_repeat	Method
CCGGGCCGAACATTCGCGGC	CRT

spacers of NZ_AP012978_3

>3.1|734502|44|NZ_AP012978|CRT
AAGAATGTTCACCTGTAGGAGGCCCGTCCCCGGGCCGAACCCTA
>3.2|734566|34|NZ_AP012978|CRT
GAGGACGCCGCTCCCACATGTAGGAGGCCCGTCC
>3.3|734620|44|NZ_AP012978|CRT
AAGAATGTTCACCTGTAGGAGGCCCGTCCTCGGGCCGAACCCTA
>3.4|734684|39|NZ_AP012978|CRT
GGGGACGCCGCTCCCACAGGTGATGTAGGAGGCCCGTCC

CRISPR arrays and Neighbor proteins around NZ_AP012978_3

CRISPR arrays

The CRISPR arrays of NZ_AP012978_3

>merge|NZ_AP012978|3|734482-734742|CRT
CCGGGCCGAACATTCGCGGCAAGAATGTTCACCTGTAGGAGGCCCGTCCCCGGGCCGAACCCTACCGGGTCGAACATTCGCGGCGAGGACGCCGCTCCCACATGTAGGAGGCCCGTCCTCGGGCCGAACATTCGCGGCAAGAATGTTCACCTGTAGGAGGCCCGTCCTCGGGCCGAACCCTACCGGGCCGAATGTTCGCGGCGGGGACGCCGCTCCCACAGGTGATGTAGGAGGCCCGTCCCCGGGCCGAACAATTTGCTG

>NZ_AP012978|3|1|734482-734742|CRT
CCGGGCCGAACATTCGCGGC	AAGAATGTTCACCTGTAGGAGGCCCGTCCCCGGGCCGAACCCTA
CCGGGTCGAACATTCGCGGC	GAGGACGCCGCTCCCACATGTAGGAGGCCCGTCC
TCGGGCCGAACATTCGCGGC	AAGAATGTTCACCTGTAGGAGGCCCGTCCTCGGGCCGAACCCTA
CCGGGCCGAATGTTCGCGGC	GGGGACGCCGCTCCCACAGGTGATGTAGGAGGCCCGTCC
CCGGGCCGAACAATTTGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_043107340.1|734755_735202_+|transposase	unknown	unknown	gnl|CDD|224854
NZ_AP012978.1|WP_148307631.1|737724_738540_-|hypothetical-protein	unknown	unknown	gnl|CDD|179854
NZ_AP012978.1|WP_043107334.1|730869_733071_+|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl|CDD|273391
NZ_AP012978.1|WP_043107344.1|738532_738922_-|DUF302-domain-containing-protein	unknown	unknown	gnl|CDD|269820
NZ_AP012978.1|WP_148307629.1|727324_727666_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_052199260.1|727653_728682_+|O-antigen-ligase-family-protein	unknown	unknown	gnl|CDD|377422
NZ_AP012978.1|WP_052199264.1|741174_741645_+|YbaK/EbsC-family-protein	unknown	unknown	gnl|CDD|239824
NZ_AP012978.1|WP_171816171.1|728929_729658_+|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|313331
NZ_AP012978.1|WP_052199258.1|723477_724473_-|GDP-L-fucose-synthase	unknown	unknown	gnl|CDD|187550
NZ_AP012978.1|WP_043107336.1|733085_733805_+|capsular-biosynthesis-protein	unknown	unknown	gnl|CDD|226870
NZ_AP012978.1|WP_043107337.1|733804_734470_+|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NZ_AP012978.1|WP_043107346.1|740249_741083_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_AP012978.1|WP_148307630.1|729678_730224_+|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|313331
NZ_AP012978.1|WP_043107342.1|735532_737635_+|elongation-factor-G	unknown	unknown	gnl|CDD|234569
NZ_AP012978.1|WP_148307633.1|743411_743717_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl|CDD|368240
NZ_AP012978.1|WP_052199265.1|743961_744843_-|hypothetical-protein	unknown	unknown	gnl|CDD|226691
NZ_AP012978.1|WP_043107331.1|726411_726963_+|hypothetical-protein	unknown	unknown	gnl|CDD|371316
NZ_AP012978.1|WP_043109171.1|730278_730806_+|polysaccharide-biosynthesis/export-family-protein	unknown	unknown	gnl|CDD|224512
NZ_AP012978.1|WP_148307632.1|739059_739932_+|hypothetical-protein	unknown	unknown	gnl|CDD|370723
NZ_AP012978.1|WP_043107350.1|743127_743406_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl|CDD|376852

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_043107340.1|734755_735202_+|transposase	gnl|CDD|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.26277e-18
NZ_AP012978.1|WP_043107346.1|740249_741083_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	0.00378647
NZ_AP012978.1|WP_043107334.1|730869_733071_+|polysaccharide-biosynthesis-tyrosine-autokinase	gnl|CDD|273391	TIGR01005, Putative_tyrosine-protein_kinase_EpsB, exopolysaccharide transport protein family. The model describes the exopolysaccharide transport protein family in bacteria. The transport protein is part of a large genetic locus which is associated with exopolysaccharide (EPS) biosynthesis. Detailed molecular characterization and gene fusion analysis revealed atleast seven gene products are involved in the overall regulation, which among other things, include exopolysaccharide biosynthesis, property of conferring virulence and exopolysaccharide export. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.18842e-81
NZ_AP012978.1|WP_043107344.1|738532_738922_-|DUF302-domain-containing-protein	gnl|CDD|269820	cd14797, DUF302, Uncharacterized domain family DUF302. These domains are mostly found in bacterial single-domain proteins and have been shown to form homodimers; they may also bind zinc. Also characterized as COG3439.	2.15982e-38
NZ_AP012978.1|WP_148307631.1|737724_738540_-|hypothetical-protein	gnl|CDD|179854	PRK04457, PRK04457, polyamine aminopropyltransferase.	9.22188e-27
NZ_AP012978.1|WP_052199260.1|727653_728682_+|O-antigen-ligase-family-protein	gnl|CDD|377422	pfam04932, Wzy_C, O-Antigen ligase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.	2.46253e-09
NZ_AP012978.1|WP_052199264.1|741174_741645_+|YbaK/EbsC-family-protein	gnl|CDD|239824	cd04332, YbaK_like, YbaK-like. The YbaK family of deacylase domains includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze mischarged cysteinyl-tRNA(Pro)'s, thus helping ensure the fidelity of translation. Organisms whose ProRS lacks the INS domain express an INS homolog in trans (e.g. YbaK, ProX, or PrdX).	5.13333e-29
NZ_AP012978.1|WP_171816171.1|728929_729658_+|outer-membrane-beta-barrel-protein	gnl|CDD|313331	pfam10082, BBP2_2, Putative beta-barrel porin 2. This domain is a putative beta-barrel porin type 2.	2.891e-08
NZ_AP012978.1|WP_052199258.1|723477_724473_-|GDP-L-fucose-synthase	gnl|CDD|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NZ_AP012978.1|WP_043107336.1|733085_733805_+|capsular-biosynthesis-protein	gnl|CDD|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	3.63809e-60
NZ_AP012978.1|WP_043107337.1|733804_734470_+|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.000733244
NZ_AP012978.1|WP_148307630.1|729678_730224_+|outer-membrane-beta-barrel-protein	gnl|CDD|313331	pfam10082, BBP2_2, Putative beta-barrel porin 2. This domain is a putative beta-barrel porin type 2.	3.14337e-13
NZ_AP012978.1|WP_043107342.1|735532_737635_+|elongation-factor-G	gnl|CDD|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	0
NZ_AP012978.1|WP_148307633.1|743411_743717_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl|CDD|368240	pfam05016, ParE_toxin, ParE toxin of type II toxin-antitoxin system, parDE. ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralized by the antitoxin ParD. The family also encompasses RelE/ParE described in.	5.59677e-13
NZ_AP012978.1|WP_052199265.1|743961_744843_-|hypothetical-protein	gnl|CDD|226691	COG4240, COG4240, Predicted kinase [General function prediction only].	5.54704e-71
NZ_AP012978.1|WP_043107331.1|726411_726963_+|hypothetical-protein	gnl|CDD|371316	pfam10961, SelK_SelG, Selenoprotein SelK_SelG. This entry inclues a group of eukaryotic selenoproteins, such as SelK and SelG. SelK seems to play an important role in protecting cells from endoplasmic reticulum stress induced apoptosis. SelG may be involved in regulating the redox state of the cell.	0.00538751
NZ_AP012978.1|WP_043109171.1|730278_730806_+|polysaccharide-biosynthesis/export-family-protein	gnl|CDD|224512	COG1596, Wza, Periplasmic protein involved in polysaccharide export, contains SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis].	1.44354e-38
NZ_AP012978.1|WP_148307632.1|739059_739932_+|hypothetical-protein	gnl|CDD|370723	pfam09849, DUF2076, Uncharacterized protein conserved in bacteria (DUF2076). This domain, found in various hypothetical prokaryotic proteins, has no known function. The domain, however, is found in various periplasmic ligand-binding sensor proteins.	0.00608025
NZ_AP012978.1|WP_043107350.1|743127_743406_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl|CDD|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	9.76515e-11

Protein sequences

>NZ_AP012978.1|WP_043107337.1|733804_734470_+|hypothetical-protein
MAARGPGLRIAASGLMVALLVVAVGAFPRGVADVYAYFVQAHLDTWAERRHLPKEQEWQRARELVRAALGWTPEDPRLLQQAGGLYEWGALIAPRAESRGAQALQYYRDSLARRPAWPYAWADLAVAKARFGQIDAEFQQAFARALETGPWEPEVQLNIARAGFLAFKRLSRANRAALARTIQRMSSRQLPELVRIAEESDSLWIVCTLRGDQPVVQRACT
>NZ_AP012978.1|WP_043107336.1|733085_733805_+|capsular-biosynthesis-protein
MIDLHCHLLPGIDDGAKDLDEALALARVAVDAGICHAVMTPHVHPGRYDNHRDGIAAACEDFQQALDAAGIALRVSPGAEVRVSDQVVLQARQGVLPTIGEWEGRPVVLLEFPHSHIPPGSEKLTAFLLRQGYQPMIAHPERNKDVIRRFEKIHPFFEQGCLLQVTAAAVTGGFGSQALKRAWQLLERGWVTVLASDAHNLHARPPDMRPGFKAVCERLDETTAWSLVRDNPARICGLA
>NZ_AP012978.1|WP_043107334.1|730869_733071_+|polysaccharide-biosynthesis-tyrosine-autokinase
MNAQDISREPVREEFDDETVDLREYWRIIHSHKWSIIGIALLFVLVVFKQRPVYQATASLLIEPESTRIVQIEDVYAVSGDDAYYRTQVEILKSRALAARVIDKLSLADNPEFLPQKDSGWSFRLNWREWFAAWLPAADEGAPDPEAEALAAREALIGDFLDRLKVAPVRNTRFVRISFEAHDPALAALIANTLADTYIESDLDARLEMTKKATAWLASRLEELKKKLRVSEQALQAYREKEKLIDSGGVGTLTAEQLQDLRQNLVVAEQERIRAQAAVSQVRAAKGDPDKLSSIPAVLNDPVVSSLKGAEVDAERRLKILAKRYGAKHPKMAAARADLQEARAAVRKRVSSVIASLVKEYQVALTNERAIRASLENAKDEMQSIHRKSYQLNVLEREVDSNRQLYEMFLRRLKETSQAGDLQKANARIADPAAVPVVPVKPKKRQIVSIAGVLGLLFGIGLAFLLERLDNTFKRASDVEERLGLPLLGAVLHLKLGKGETPLDYARSHPQSRFAESIRTVRTSVLLSGLDEPYKVIVITSSVPGDGKSTLAMNLADSLGEMHKVLLIDADLRRPTVATTWGLDRKAKGLSEFLSQSANASECVHQLDERNVYVMPSGVVPPNPLELLSSRRFKEALDTLGRTFDHIIIDSAPALAVSDALVLSRNASGVIYVIKADSTPYPAAQEGIKRLRHYKAHLIGAVFNDVSQKKKKGYGYYDGDGGGYYASYGYTQD
>NZ_AP012978.1|WP_043109171.1|730278_730806_+|polysaccharide-biosynthesis/export-family-protein
MEGGLVVLLSCLLGNMALAAQALDNYRLGAGDKIRIQVYGEKDLSVETLVDDSGTISYPFLGEIQVKGSTLREVEQRITEGLRGDYLVNPEVTVSIVEYRHFYVNGWVKSPGSFPFQPGMTVRKAISLAGGFAERANKRALTVVHGDDAFGKPQQIHLDDQLHPGDIISVGRSFF
>NZ_AP012978.1|WP_148307630.1|729678_730224_+|outer-membrane-beta-barrel-protein
MTFDLDLQKINYDVAALDSTELRGLVGVRWEATFQTAGFAKAGWQKKNMSSAGLSDASGASWELGVDWKPLSYSSFQLSTSRDFGESDGVGSYQDTRSLGLAWNHDWTDVLGTRLSLDKSRIEYGGSTRRDRNRSFGIDVEYRAPPWLLFGATISHSRRDSNQAGLDYKDNQFGVQVGINM
>NZ_AP012978.1|WP_171816171.1|728929_729658_+|outer-membrane-beta-barrel-protein
MDMSLQGKNRGWVAMAAAMLPLLMTGQAHAIKGGEPGTVILDGGMFYPSIGIALTHDDNIFRTDTNKKSSTLLVLTPGARLEYDAGEATQVAFELDMERGVYFDSSDDNYLDVDLFSEAAYLPTERLTFYGRLGYKRGHEARGTGTSAGTPLAISEPDRFHVWSGEGRVSYDIGEQKLEFGYVHEKRLTVSMSGPARGGSAMALASRSSSSATFTKSASTTTTARRPSCRIASPTPCRPGCR
>NZ_AP012978.1|WP_052199260.1|727653_728682_+|O-antigen-ligase-family-protein
MFWLKSLSCLLVFVLTLALVNSRARLRRLMWVLVFSGAFQAVYGSLMVMSGLEWGFFFHKDTGQGVATGTFINRNHLAGYLELCLALGIGLLLAGLEEERVLGWRQRLRHWVRTLLGPKLRLRVLLAAMVVGLVMTHSRMGNSAFFTSLLVTGGLWLVATGRRSWSGPLLLLGSLLLIDTFIVGHWFGVERVMQRIEQTRIETEQRRYVAEDTLAPVRDFWRTGSGAGSFYTVYPAYRDGIVQGFYDHAHNDYLELAVETGLPGSALLLFIALPSWWMGMRAMWRRRRRLYRGAGFAVIMAGIAFAMHSSVDFNLQIPSNAILFVVLLALGWVAAYQRPSEN
>NZ_AP012978.1|WP_148307629.1|727324_727666_+|hypothetical-protein
MGFLALLLWLPLPVGSNRVWAVVLMYTLLSLLAAWWLGLWLRHRVEPGPALMQARWVLLVFVLWLVWLALQRLPLPPGGLSWLSPRAWQAWREVDPQGTAPVSLEPWAGGCSG
>NZ_AP012978.1|WP_043107331.1|726411_726963_+|hypothetical-protein
MKNKIGVVLALCLMGVAMPGMVLADEDKGGQAAEQAQSAEAMLQALLDQGMPVEKALKKVLEKYPEAAPNLIAKAVQAALAQKGEADKTIEKIVKVAQETLGEGGEQAAIAQGLLLAGVDPEPYLEATAAGKKDKDKKKKKKKKDDDNGNDDNGNDGNTDTGTGGGLPGGGGGGGGGGGVSPS
>NZ_AP012978.1|WP_052199258.1|723477_724473_-|GDP-L-fucose-synthase
MAFLDDAGARVYVAGHRGMVGSAILRALKRAGFANLLTRTSAELDLRRQAEVEDFFAQERPDYAFLAAARVGGILANDSYPADFLYDNLAIEANIIHAAHRTGVKKLLFLGSTCIYPKLAPQPLKEEYLLTGPLEPTNEWYAVAKIAGIKLCQAYRKQHGDDFISAMPTNLYGPEDNFDLEKSHVVPAMMRKMHEARERGEAEVPLWGTGKPLREFLHVDDLAEALLFLMQHYSDAEHVNVGVGQDLSIRELAETIARVVGYQGELAFDPTKPDGTPRKLVDTTKINALGWHPRIGLEEGLRDTYRWYLANRDRLRGQDRQATAKEPLINS
>NZ_AP012978.1|WP_043107340.1|734755_735202_+|transposase
MVPVYHGKDLRKGRVSIPGQIYHVTTVTRAREPVFQDLNSARRVIQVLMEIQSHELADTLAFVVMPDHVHWLLQLGERRPLSCVIASMKSISARRIGRGKIWLAGFHDHALRRDEDLRQVARYIVANPLRAGLVDDIGHYPHWDAIWL
>NZ_AP012978.1|WP_043107342.1|735532_737635_+|elongation-factor-G
MTDLTLYRNIALYRNIGIFAHVDAGKTTTTERILNLTGKTHKIGEVHDGEATTDFMDQERERGITIQSAATTCFWKDHRLNIIDTPGHVDFTIEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYANESEVARIIFVNKLDRMGADFYRVVKQVEDVLGANPLVMTLPIGIEDEFVGVVDLLTRKAWIWDDSGDPHKYHIEDVPADMTDKVEEFREKLIETAVEQDDDLMEAYLEGEEPSIEDVKRCIRKGTINLDFFPTYCGSAFKNKGIQLVLDAVVDYLPNPTEVKPQPEVDLEGNETGEYAIVDPDRPLRALAFKIMDDRFGALTFTRIYSGRLKKGDTVLNTYTGKTERIGRIVEMHANERKELDSAQAGDIIALVGLKNTQTGHTLADPNNPATLEPMVFPDPVISIAIKPKDKGSTEKLGVALNKMMQEDPSFRVETDEDSGETIIKGMGELHLDIKVDILRRTHGVDVEMGKPQVAYRETITKRVEDSYTHKKQTGGSGQFAKIDYVIEPGEPNSGFQFESTVTGGNVPREFWPAVEKGFAVSMQEGPLAGFPLLDVKVTLVDGGFHPVDSSAIAYEIAAKGAYRQSVPKAGPQLLEPIMKVDVFTPEDHVGDVIGDLNRRRGMIQGQESGPTGVRVKAECPLSEMFGYIGDLRTMTSGRGQFSMEFSHYAPCPANVAEEVIKETKARKEAG
>NZ_AP012978.1|WP_148307631.1|737724_738540_-|hypothetical-protein
MAETTDKPHPLGRIVARREDACGPVEVRELGQHRFLTFGNVVEQSCCNTAQPWRLEHVYTQAMMLGLLLRPDPGSALILGLGGGSLVRALRHAAPDLRLAAVESRQAVIELAIEWFGVDPGDPQLRLHCADAADFVAGTQERFDLIFADLYLAEGVNPVQTRLDFLEHTRERLARHGLLLLNAWCSEFRDARETHQALDAVFGEFRLALHVQGGNSIIFAFRDHLPVVDRNRLFSSAQAMGLRLDIPLQRLARTLWRQNAQALRSGRYRPG
>NZ_AP012978.1|WP_043107344.1|738532_738922_-|DUF302-domain-containing-protein
MYEFNLTLDLPFEQALEKVREALMSEHLGIVSEVDVQAIFKAKMDKDIPPYRILGACNPKLADRVLSVEPNAGTLLPCNLVLRDAGDDKTVVSFMDPVAVLGLSESAEVRAVAEEARDKLQRVVAGLGG
>NZ_AP012978.1|WP_148307632.1|739059_739932_+|hypothetical-protein
MKQSIKSLSAAILLGLASGAGQVLAQGYPQGGYSAPPQPPAVPYGYAQPGYGDYGYGQYPGYGYQAPPSAGAYAYPGAQGYYPPAYGSSMPYGGFPRGFGKKRWDDWDLFGGDNPLQNPLDHEGYWAHPRFQPWRSGPFAHDKWRDHPMKQMPWGNFPGWGDGFFGGYGPDRWKGVTPWGNDVPFKWIDPSDPEESIANMWEDAINTPYNMGRMPPGWTAPQISVPNPIDVENEFERNFRNAPTEFRNMWGEEGAGFGSAGKPKAKKAEKKPQQNPQEKPAAAKPAPADR
>NZ_AP012978.1|WP_043107346.1|740249_741083_-|class-I-SAM-dependent-methyltransferase
MSRTRNRKQKADMASQADRHRLYELAVQCAEAEVDFVIDTFRELRGRKPLHLREDFCGTANVCCEWVRRGARHTAVGVDLDGEVLDWGRRHRLGALTERQRSRVALLQDDVLDAQTRPTDVVLAMNFSYWLFKQRSDLLRYFRSVHNNLVDDGIFFLDAYGGYDAFREIDEEREIDDGGEGFTYIWDQDHFNPVDNNLVCHIHFAFPDGSVMERAFTYDWRLYTLPEIRDLLDEAGFSRTTVYWQGWDEDGEASGEFYPTETADADAGWICYLVAEK
>NZ_AP012978.1|WP_052199264.1|741174_741645_+|YbaK/EbsC-family-protein
MAVAATIQNYLDSHGIEYEIIEHPRTDNPKQSAQVAHVPPEQMARPVLLGDDINYLLAVIPANHRLDLDRLNQVMARSLELVDGEELEFTFSDCEKGAIPPVGEAYGVDTVLDVALSHQEAIYFEAGDHKHLVHVRGDDFRRLMEHVPRVQASHHL
>NZ_AP012978.1|WP_043107350.1|743127_743406_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MGVKFSEDVVPLTDLKINPGKVVRHATEAHRPVLLTSRGRGVAVVQSVADYEASEEERDFMRAVVAGLADLDAGRELSLEEAKSRLGLSASE
>NZ_AP012978.1|WP_148307633.1|743411_743717_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MGEVTIRFAESAVADLEKIRLWYAEQGVPDAGERLVTEIFQRIEALEKHPELGRIVPEFDQPFLRELIQPPFRIVYRHDPGKVRIVRVWRSERLLRLPEAP
>NZ_AP012978.1|WP_052199265.1|743961_744843_-|hypothetical-protein
MNRTEEILRNFMAKHGLPAAFADAAHQHYLPLAKTLDHLRERLGRPLVAGIHGCQGSGKSTLAELLTAWLAQVHGRRCVALSIDDFYLTREQRRELAERVHPLFITRGVPGTHDTALLDRTLDALTLASGTVAIPRFDKITGDRQPEHEWPRTRTPVDIVILEGWCLGVQPQDPAALMSPINRLEAEEDPDGRWRQYVNDCLRTDYLPLWERIDYWTMLAAPSFDCVFEWRMEAERGLRAQGNGQHLMDETAMQRFIEHYQRLTEHALATLPPHMDQLIRLDEQRCVQSSSKP

Crispr_ID: NZ_AP012978_4

• CRISPR_ID: NZ_AP012978_4
• CRISPR_location: 820977-821172
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_AP012978_4

Consensus_repeat	Method
CCTGTGGGAGCGGCGTCCCCGCCGCGAA	CRT
TGTGGGAGCGGCGTCCCCGCCGCGAA	CRISPRCasFinder

spacers of NZ_AP012978_4

>4.1|821005|31|NZ_AP012978|CRT
CATTCGGCCCGAGGACGGGCCTGTTGCACCA
>4.2|821064|22|NZ_AP012978|CRT
TGGTTCGGCCCGGGGACGGGCC
>4.3|821114|31|NZ_AP012978|CRT
CATTCGGCCCGAGGACGGGCCTGTTGCACCA
>4.4|821005|33|NZ_AP012978|CRISPRCasFinder
CATTCGGCCCGAGGACGGGCCTGTTGCACCACC

CRISPR arrays and Neighbor proteins around NZ_AP012978_4

CRISPR arrays

The CRISPR arrays of NZ_AP012978_4

>merge|NZ_AP012978|4|820977-821172|CRT,CRISPRCasFinder
CGTGTGGGAGCGGCGTCCCCGCCGCGAACATTCGGCCCGAGGACGGGCCTGTTGCACCACCTGTGGGAGCGGCGTCCCCGCCGCGAATGGTTCGGCCCGGGGACGGGCCTCCTACAGGTGAACATCCCCGCCGGGAACATTCGGCCCGAGGACGGGCCTGTTGCACCACCTGTGGGAGCGGCGTCCCCGCCGCGAA

>NZ_AP012978|4|2|820977-821172|CRT
CGTGTGGGAGCGGCGTCCCCGCCGCGAA	CATTCGGCCCGAGGACGGGCCTGTTGCACCA
CCTGTGGGAGCGGCGTCCCCGCCGCGAA	TGGTTCGGCCCGGGGACGGGCC
TCCTACAGGTGAACATCCCCGCCGGGAA	CATTCGGCCCGAGGACGGGCCTGTTGCACCA
CCTGTGGGAGCGGCGTCCCCGCCGCGAA

>NZ_AP012978|4|3|820979-821063|CRISPRCasFinder
TGTGGGAGCGGCGTCCCCGCCGCGAA	CATTCGGCCCGAGGACGGGCCTGTTGCACCACC
TGTGGGAGCGGCGTCCCCGCCGCGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_171816174.1|816329_817199_-|3',5'-cyclic-AMP-phosphodiesterase	unknown	unknown	gnl|CDD|182997
NZ_AP012978.1|WP_052199274.1|814009_814561_+|thioredoxin-fold-domain-containing-protein	unknown	unknown	gnl|CDD|239249
NZ_AP012978.1|WP_043107453.1|824399_826133_-|proline--tRNA-ligase	unknown	unknown	gnl|CDD|236405
NZ_AP012978.1|WP_043107457.1|828935_830603_-|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl|CDD|236992
NZ_AP012978.1|WP_043107439.1|812878_813277_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043107448.1|820363_820951_+|DUF3501-family-protein	unknown	unknown	gnl|CDD|378790
NZ_AP012978.1|WP_043107450.1|821236_821752_-|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabA	unknown	unknown	gnl|CDD|179953
NZ_AP012978.1|WP_171816175.1|821875_823240_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|223715
NZ_AP012978.1|WP_052199277.1|831870_832965_+|CZB-domain-containing-protein	unknown	unknown	gnl|CDD|223910
NZ_AP012978.1|WP_043107460.1|830659_831517_-|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	unknown	unknown	gnl|CDD|236760
NZ_AP012978.1|WP_070104758.1|826239_826944_+|transglutaminase-like-cysteine-peptidase	unknown	unknown	gnl|CDD|226198
NZ_AP012978.1|WP_043107447.1|819015_820344_+|Fe-S-oxidoreductase	unknown	unknown	gnl|CDD|236869
NZ_AP012978.1|WP_043107437.1|811802_812951_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_148307642.1|815732_816326_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_AP012978.1|WP_043107455.1|826940_828884_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NZ_AP012978.1|WP_043107446.1|818528_818948_+|rubrerythrin	unknown	unknown	gnl|CDD|153100
NZ_AP012978.1|WP_171816265.1|833542_834784_+|serine-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234571
NZ_AP012978.1|WP_081999800.1|814563_815736_+|TolC-family-protein	unknown	unknown	gnl|CDD|224455
NZ_AP012978.1|WP_043107441.1|813495_814005_+|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NZ_AP012978.1|WP_043109193.1|823266_824169_+|response-regulator	unknown	unknown	gnl|CDD|381093

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_171816174.1|816329_817199_-|3',5'-cyclic-AMP-phosphodiesterase	gnl|CDD|182997	PRK11148, PRK11148, cyclic 3',5'-adenosine monophosphate phosphodiesterase; Provisional.	2.62267e-79
NZ_AP012978.1|WP_052199274.1|814009_814561_+|thioredoxin-fold-domain-containing-protein	gnl|CDD|239249	cd02951, SoxW, SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide fixation during autotrophic growth and the respiratory electron transport chain. It is unclear what the role of SoxW is, since it has been found to be dispensable in the oxidation of thiosulfate to sulfate. SoxW is specifically kept in the reduced state by SoxV, which is essential in thiosulfate oxidation.	4.86109e-38
NZ_AP012978.1|WP_043107453.1|824399_826133_-|proline--tRNA-ligase	gnl|CDD|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
NZ_AP012978.1|WP_043107457.1|828935_830603_-|energy-dependent-translational-throttle-protein-EttA	gnl|CDD|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0
NZ_AP012978.1|WP_043107448.1|820363_820951_+|DUF3501-family-protein	gnl|CDD|378790	pfam12007, DUF3501, Protein of unknown function (DUF3501). This family of proteins is functionally uncharacterized. This protein is found in bacteria and archaea. Proteins in this family are about 200 amino acids in length. The structure of protein BPSS1837 from B. pseudomallei has been solved. This protein contains two domains, domain I (1:31, 46:81) is a helical domain, domain II (32:45,82-193) is a mainly beta protein with a beta barrel. According to crystal contacts the proteins probably functions as a dimer. The gene neighborhood analysis suggests that this protein may be functionally related to rubrerythrin and ferredoxin. The wedge surface between the two domains might be functionally important. The fold of this protein could best be described as a circularly permuted C2-like fold (details derived from TOPSAN).	1.48012e-102
NZ_AP012978.1|WP_043107450.1|821236_821752_-|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabA	gnl|CDD|179953	PRK05174, PRK05174, bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase.	2.78607e-129
NZ_AP012978.1|WP_171816175.1|821875_823240_+|PAS-domain-S-box-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	7.02413e-57
NZ_AP012978.1|WP_052199277.1|831870_832965_+|CZB-domain-containing-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	2.82411e-29
NZ_AP012978.1|WP_070104758.1|826239_826944_+|transglutaminase-like-cysteine-peptidase	gnl|CDD|226198	COG3672, COG3672, Predicted transglutaminase-like cysteine proteinase [General function prediction only].	1.31669e-31
NZ_AP012978.1|WP_043107447.1|819015_820344_+|Fe-S-oxidoreductase	gnl|CDD|236869	PRK11168, glpC, anaerobic glycerol-3-phosphate dehydrogenase subunit C.	2.29596e-82
NZ_AP012978.1|WP_043107460.1|830659_831517_-|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	gnl|CDD|236760	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
NZ_AP012978.1|WP_148307642.1|815732_816326_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	6.69431e-16
NZ_AP012978.1|WP_043107455.1|826940_828884_+|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	2.18239e-54
NZ_AP012978.1|WP_043107446.1|818528_818948_+|rubrerythrin	gnl|CDD|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	7.26428e-62
NZ_AP012978.1|WP_171816265.1|833542_834784_+|serine-hydroxymethyltransferase	gnl|CDD|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_AP012978.1|WP_081999800.1|814563_815736_+|TolC-family-protein	gnl|CDD|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	5.84395e-19
NZ_AP012978.1|WP_043107441.1|813495_814005_+|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	2.92239e-39
NZ_AP012978.1|WP_043109193.1|823266_824169_+|response-regulator	gnl|CDD|381093	cd17538, REC_D1_PleD-like, first (D1) phosphoacceptor receiver (REC) domain of response regulator PleD and similar domains. PleD contains a REC domain (D1) with the phosphorylatable aspartate, a REC-like adaptor domain (D2), and the enzymatic diguanylate cyclase (DGC) domain, also called the GGDEF domain according to a conserved sequence motif, as its output domain. The GGDEF-containing PleD response regulators are global regulators of cell metabolism in some important human pathogens. This model describes D1 of PleD and similar domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.21512e-33

Protein sequences

>NZ_AP012978.1|WP_043107448.1|820363_820951_+|DUF3501-family-protein
MKHQLTRDDLYSLEQYAEVRPDFRARVMAHKQDRRVPIGPNATLYFEDALTMQYQIQEMLRIERIFEAEGIQEELDAYNPLIPDGSNWKATFMMEYPDENERREQLKRLLGIEKHVWIQIGDLPRVTPIADEDLEREDEEKTSSVHFLRFELTPEMVEAVKKGAPVAMGIDHPNYTYTVEQIPENVRKSLVNDLD
>NZ_AP012978.1|WP_043107447.1|819015_820344_+|Fe-S-oxidoreductase
MAASREGSLEAPTRHPIDWRNPDYYDEDKLFTELERVYDVCHGCRRCVSLCNAFPTLFDLVDESDTMEVDGVAKDDYWKVVDQCYLCDLCFLTKCPYVPPHEWDVDFPHLMLQAKAVKYRKQGASLRDRTLTSTDALGSIAGIPVVAGVVNTLNRNAGFRKLLENTFGVHRDARLPEFHSKPLRARIQPDTGEGAEPTGPTTGKVVLFATCYGNRNDPKTGEDLVAVLRHNGIRVTLAEKERCCGMPKLELGDLEAVAEAKEVNIPVLARLVDEGWDIVAPVPSCVLMFKQELPLMFPDDPEVAKVRDAIYDPFEYLMLRHKHGKLNTDFKNPLGKIAYHAACHQRVQRIGPKTRELLSLVPGTEIQTIERCSGHDGTYAVKKEFHAASMKIGRPVYNKVKQAQPDHYSSDCAMAGQQIANGLGDGSEPEHPISLLRLAYGI
>NZ_AP012978.1|WP_043107446.1|818528_818948_+|rubrerythrin
MSLKGSKTEENLKAAFAGESQANRRYLYFAAKADVEGYNDVAAVFRSTAEGETGHAHGHLEYLEEVGDPATGLPIGGTADNLKAAIAGETHEYTDMYPGMAKTAREEGFDEIADWFETLAKAERSHANRFQKALDALDS
>NZ_AP012978.1|WP_171816174.1|816329_817199_-|3',5'-cyclic-AMP-phosphodiesterase
MSHGNPSIPASFRRARERDLHKVSLPPECLKVLQITDTHLYADTNSRLLGVNTMDSFRNTITTFRHTGWRPDLVLATGDLVHDASPEGYQRLAQLLDEFGCPVYCLPGNHDLPDVMRKHLRGRHVSCPQVVDHKGWRLVLLDSVLAGQVGGHLAESQLELLDGALREHDGPVLVSLHHQPVPVGSHWIDDMGLDNADALLKRVTAHPQVKGLLWGHVHQLFDKRLDGIRLLGTPSTCVQFTPSVDEFSVDQQQPGFRLLALMPDGEILTEVLRARHLPHGLEVASAGYE
>NZ_AP012978.1|WP_148307642.1|815732_816326_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MKPGNVRRMCWLSLVWLWLGIVPLSWAGELVGTLEWNREVTLGVLEPGVIQTVRVVPGQRVRRGELLLALDRRAQKADLAAARGRLQLAQARLEEAQREFERAEDLYERTVLSEHERVVAHIGLLEAPFDGLVVRVDARPGQAVNGTLAVPELLVLADDHQFRVRLWVDAATLDALKAAQALHVELAGRRLPVRVFW
>NZ_AP012978.1|WP_081999800.1|814563_815736_+|TolC-family-protein
MRWWCLLGPCLLGALSLAAVAAVRESAALEGVHLTLGGELRLIQPSSLATNQDHNDSRAHLLLEKRLYDAGYSTARETAAQARLEAGQWRVRAARQEQALAIMQAFYDVLLADLAFARDNEAMSVAYVRLDRGRDRHELGQLSDLDLLALESRYEETHRAQLRSAARQRTARSRLALVLGRPGELSSELVMPDIEVKAPSGETFETFWDQVRERHPRLRALVAELRAARAALAAARASQGPVLSARVEAGAWHRRTGSTHPLAGGVHVEWPLLDAGRREAAVVRAEAALTRAQAAWQAGLQEVRQQALEAWLARETLAAELKSLQGEEDYRDLYLDRSRALYEQEIKTDLGDAMVRISEVRLKTAQVRFDWALNEARLRAMTGELLEDLP
>NZ_AP012978.1|WP_052199274.1|814009_814561_+|thioredoxin-fold-domain-containing-protein
MGRFGKRVLVGWLWYCLLVGTALAQPGRDPDQYFFNETFWDLKEELANAREQGKQGILIMFEMDECPFCHRMRQTVLNQPEVQEYFRQHFINIAIDIEGDVEVVDFQERSTTMKDFAFRQYRVRATPVFAFFDLDGKYIRRARYTGATRDKKEFLLLGRYVVEQAYRKESFARYKRRMRKREH
>NZ_AP012978.1|WP_043107441.1|813495_814005_+|TlpA-family-protein-disulfide-reductase
MKRLRRSWPLGVLLVWCLAGVAWASPDFALPDLHGKVHRLSDYRGKWVLVNYWATWCPPCREELPELESFYAGSDGERVVLGVNIEDIGKEELAVFVDEQFLSYPILLAGARPEHDQLLGPIRGLPTSYLISPQGKVVARQVGPVSAKDIEDFIEHYEEQASAERAPRG
>NZ_AP012978.1|WP_043107439.1|812878_813277_-|hypothetical-protein
MDIPQPLIARHPDAIVNVRELRSWLEELPPTNPKYTIQQLQRQLAFLVRDPQPARRYEELLRCYHEPVATLQTQALDALGTQPVARTRNQRDLLEPFPGLLQENWPARTCAPRRCVCPTASRQTRPICMPPC
>NZ_AP012978.1|WP_043107437.1|811802_812951_-|hypothetical-protein
MRAAQMRLSDGKPPNPSDLHAALLMLGRIIQHNMIEHQMLRPTIWRQMVQLYNVAERHDLGQVTCESPLCLTRDPATANGAFFSALVLLLSDPHRHSVRCIQQLVRELPGAVDALRLSRETKDRYRIPVDLSGESTPLEFSRRPTNQGQARKVYLHGLNAMLQKLPAEEDEPRPCRLRHWLAADLGGLIAGRRERRHPRQIRNADYHFIQGFEAVHQRLTELQSGREQLEYTGEPPSGGIPCRQNDASFGGASFLLPARVPIPEPGEWLLFELDYPPGSQEHSGFVAQMRRRLVDDNRYQYIGVERLVGHVTPVTLGSTRQPALLNADRSHSHFQLIAPLGHFTGEGTIETLEGINKHYQVRHERRAAQFPDTEIIHVSLLD
>NZ_AP012978.1|WP_043107450.1|821236_821752_-|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabA
MSRQESFDREALLRCGHGEMFGPGNAQLPVPPMLMMDRINLISDEGGKYDKGQIIAELDIRPDLWFFDCHFPGDPVMPGCLGLDAMWQCVGFFLAWIGNPGHGRALGVGEVKFTGQVLPTAKKVTYYLDMKRVISRKLVLGIADGRMEVDGRQIYEANDLRVGLFTSTEGF
>NZ_AP012978.1|WP_171816175.1|821875_823240_+|PAS-domain-S-box-protein
MEVSRIGEDTSRTESHRSGDADRCAEVEQLRAQVEQLTAAGTELVSTQTRMQSLLHNASDAIILFEGDGTIGLFNRAAEHLFDVAEIEVLYQKGEQLFDLPEEFAGNVPAYLSYHVRNTPDQYANPLVALRSSGERRLVEVSIAEIASNDLVLFDDFAEDALEENGANSGFDAFLCILRDITERKAIDAELQAHREHLEELVEEQVREIREAKEQAERANRAKSEFLANMSHELRTPMHAILSYADFGKKKYDRAPPEKLLQYFERIHTAGSRLLEMINDLLDLAKAEAGRLEYHLQETRLDEVIRPVLEEYEALAASKGLRLVYESEADLPPCLMDPERIGQVVRNYLSNAFKFSPRGGTVTLRVRRATLTAGEATIPALELAVCDQGCGIPEGELEQVFDKFVQSSGSPKDMGGTGLGLAICREIAEAHGARVWAENAPGGGARFYLCLPIE
>NZ_AP012978.1|WP_043109193.1|823266_824169_+|response-regulator
MSHTPRLLIVDDEPLNIEILLEYLEDGGYELDTAEDGQEAWEKLEAAPDYYDVVILDRMMPRMNGMEVLSRIKAHPVMQSIPVILQTALAAHDEILEGIQAGAWYYLTKPFEEDLLRSVLGTAIEDRMRYRRMQEESSMASRTFGLLHEARFRFRTLESARDLATMLANACPQPGKVVIGLSELLINAVEHGNLGITYDEKSVLREEHRWEEEVTSRLQDPVLGAREVEVCYLRGDEAIEITITDEGDGFDWQAYLDMDPARAFDTHGRGIAMSRMISFERLEYRGCGNEVVAIIELAEG
>NZ_AP012978.1|WP_043107453.1|824399_826133_-|proline--tRNA-ligase
MRVSRFPLQTLKEVPADAEIPSHRLMLRAGMIRKLASGLYTWLPLGLRVLRKVETIVREEMDRAGALEVLMPAVQPAELWEESGRWYKYGSELLRFEDRHGRPFCFGPTHEEIITDLARNELRSYRQLPVNFYQIQTKFRDERRPRFGVMRAREFLMKDAYSFHLDDESLAETYEVMHATYCRIFERCGLEYRPVEADTGSIGGRASHEFHVLAETGEDDIALSDGGYAANVELAEALAPGEAPEAPTEEKRLVDTPNARTIDELVEQFDVPIERTLKTLIVRAAEDADAELVALVLRGDHELNEIKAIKHPLVADPLVMADEEAIRAAVGASPGSLGPIDLPMPVIVDRAAAVASDFTCGANQDGKHWFGVNWERDLPLPEVADLRKVVEGDPAPDGSGPLRIVKGIEVGHIFQLGRTYSEKMNATVLDENGKSVVMTMGCYGIGVSRVVGAAIEQHHDDRGILWPTALAPFELALIPMQMHKSETVREAAERLYAELRAAGIDVLFDDRDARPGVMFADAELIGIPHRVVVGERGLKNGEVEYRARTAEENEMIPLERFVDFIRERIERERNQGE
>NZ_AP012978.1|WP_070104758.1|826239_826944_+|transglutaminase-like-cysteine-peptidase
MSAIARTLPPLSVEAAAIRWWLAAVLACLLTWAGSQSQVLMFNEALYRWVEQEYGSEARLRVERLQRLVETHLNDAEIDKIRVVNRFFNQVRYDEDDVLWDQKDYWATPFEVLGLNAADCEDYALSKYFTLVSMGVPEERLRITYVKAVEIGRAHMVLAYYPTPDAEPFILDNLIDRIEPASKRTDLVPVYSFNGADLWLAVNRVEGRKVGGSDRIKRWQAFQKKLRQQMGAHS
>NZ_AP012978.1|WP_043107455.1|826940_828884_+|EAL-domain-containing-protein
MSLSKQLVVLITTLVLLLFAGTFLISVHNTRDYLENQLASHAQDAATSLGLSATAHVASGDQAMFTSMVNAMAHRGDYLSIRIEDLDGRVLVERRADFRTEVPQWFMDLFPLHPPEGSAVMMSGWHQVGKVRVVSHPGLAYRKLWNTAVDTLVWFFVAAGGLLLLALVLLRWMLQPLKKVEWQAEAICNREFPVVEERPFTLEFRRVVEAMNRLSTKVRQMLDNAERLAERLREQAYTDALTGLANRRHFMAVLESRLADEQSAGGLLLVQIRDFKAFNDTRGYQSGDQLLVAVADLLRQETAGLEGTTLAHVAGADFAVLCEGLDEARLRELAARIAAALGGLCAVQEGLPDDVGQVGGVMYRDQEVGELLAQADLALRQARQAGGNSWVVLESARSACVTRSATQWREAIERALDKGFFQMQAQGVYAADGTLLHRELFLRLIDLEDEGAIVPAGVFVPVAESLGLAVRIDRWVVTEVCERLSGVFGEERLAINLSSGSLVEVECLDWVEQTLRAHPEVARRLVLEWAEYTAQAHPQRLREWIDRLAPLGVEFSLDHFGKGFSAFAALRELKVHYLKIDAAFTRDLEQDPKDTFFLHAVTDIAHGLELRVIAEAVESGTVWERLRETGIDGGRGYFLGEPEDVRA
>NZ_AP012978.1|WP_043107457.1|828935_830603_-|energy-dependent-translational-throttle-protein-EttA
MAQYIFTMNRVSKIVPPKRQILRDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDTDYEGEARPQPGIKIGYLPQEPQLDPEKDVRGNVEEALGEVKQAMDELEKVYAAYAEPDADFDALAKRQAELENIIQAADGHNLERQLEVAAEALRLPPWDADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERFLHDYPGTVVAVTHDRYFLDNVAGWILELDRGHGIPWEGNYSSWLEQKEKRLEQEQKAEQARIKAMKQELEWVRSNPKGRHAKSKARLKQFDELQNQEFQKRNETNEIYIPPGPRLGDLVIEAKHLKKAYGDKVLYEDLSFNLPPGGIVGIIGPNGAGKTTLFRIMTGAEQPDDGELRIGPTVKIAAVDQSRDALDPNKTVWEEISDGQDIITVGNYQVQSRAYCSRFNFRGSDQQKKVGDLSGGERNRVHLAKLLKSGGNLLLLDEPTNDLDVETLRALEEAILAFPGCVVVISHDRWFLDRIATHILAFEGDSKVVWFEGNFADYEEDKKRRLGEDAVNPKRIKYKRIDA
>NZ_AP012978.1|WP_043107460.1|830659_831517_-|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD
MSAQILDGKAIATDVREQVRLQVEQRVTEGQRPPGLVVVLVGENPASQVYVRNKQLACEKAGFKSELIQLPNDTSQEVLLELIDGLNARDDVDGILVQLPLPVQIDEHAVTERIHPDKDVDGFHPYNIGRLALRMPVLRPCTPKGVMTLLAHTGVELEGKDAIVLGQSNIVGRPMLLELLAARCTPTICHSRTRDLADKVRQADIVVAAVGVPNFVQGDWIKPGAIVIDVGINRLDDGSLCGDVDFEAAREVAGWITPVPGGVGPMTVATLLENTLQAAQLHTGT
>NZ_AP012978.1|WP_052199277.1|831870_832965_+|CZB-domain-containing-protein
MAELESENQALRARLAEVEAALAQEREDGQRKVAWCDCVEHQAALTLRSERALDDIRNQAGQGAARLLDEQKQLNESSRLFSQSTVFLEAVRSQVEEVARSAASGQETVNNLDEAVQAIHQFTDTIAEISDQTNLLALNAAIEAARAGEQGRGFAVVAEEVRSLAAKTADATDRIKDHVQRVTGYADETKAGFEGMVDASSRMLEQTDQINDVIGEVTYLSQGMIQTISRNAAGAFIEVVKLDHILYKLAIYKVLAGKSDKSPDDFASHHHCRLGKWYFEGDGAQLAGSPVYQQLDEPHAVVHEAGARALRARQAGDNEGCLAALEEMEDASDRVITLLGELEETYYQRMLGSVDTGASKVDLF
>NZ_AP012978.1|WP_171816265.1|833542_834784_+|serine-hydroxymethyltransferase
MKIEGYDDELFRAIRDEERRQEDHIELIASENYCSPRVMEAQGSVLTNKYAEGYPAKRYYGGCEYVDRAEQLAIDRAKALFGADYANVQPHSGSQANAAVYMALCQPGDTVLGMALAHGGHLTHGARPNFSGKIYNAVQYGLDPETGEIDYEEVERLAREHKPKMIVAGFSAYSRIVDWQRFREIADSVGAWLMVDMAHIAGLVAAGVYPSPVQIADVTTTTTHKTLRGPRGGLILARANEEVEKKLNSAVFPGIQGGPLMHVIAAKAVAFKEAMEPEYVEYQKQVVRNAQVMAQVFIERGYDVVSGGTDDHLFLVSFIEAGLTGKDVDAWLGAANITVNKNAVPNDPQSPFVTSGIRVGTPAVTTRGFGEDECRQLASWMCDVIDGRGDTAVIERVKGQVLDLCTRYPVYRG

Crispr_ID: NZ_AP012978_5

• CRISPR_ID: NZ_AP012978_5
• CRISPR_location: 878838-878928
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP012978_5

Consensus_repeat	Method
TTCGGCCCGAGGACGGGCCTCCTACAGGCCA	CRISPRCasFinder

spacers of NZ_AP012978_5

>5.1|878869|29|NZ_AP012978|CRISPRCasFinder
TGTGGGAGCGACGTCCTCGTCGCGAACGG

CRISPR arrays and Neighbor proteins around NZ_AP012978_5

CRISPR arrays

The CRISPR arrays of NZ_AP012978_5

>merge|NZ_AP012978|5|878838-878928|CRISPRCasFinder
TTCGGCCCGAGGACGGGCCTCCTACAGGCCATGTGGGAGCGACGTCCTCGTCGCGAACGGTTCGGCCCGGGGACGGGCCTCCTACAGGCCA

>NZ_AP012978|5|4|878838-878928|CRISPRCasFinder
TTCGGCCCGAGGACGGGCCTCCTACAGGCCA	TGTGGGAGCGACGTCCTCGTCGCGAACGG
TTCGGCCCGGGGACGGGCCTCCTACAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_043107493.1|883764_885084_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|182754
NZ_AP012978.1|WP_052199292.1|879782_880475_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_148307649.1|872742_873273_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_148307648.1|871633_872005_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043107490.1|878991_879795_+|ferritin-like-domain-containing-protein	unknown	unknown	gnl|CDD|377292
NZ_AP012978.1|WP_043107495.1|885766_886030_-|hypothetical-protein	unknown	unknown	gnl|CDD|377032
NZ_AP012978.1|WP_171816179.1|875917_876088_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043107498.1|886045_886609_-|glycine-zipper-2TM-domain-containing-protein	unknown	unknown	gnl|CDD|225676
NZ_AP012978.1|WP_052199291.1|876120_876816_-|GTP-binding-protein	unknown	unknown	gnl|CDD|349766
NZ_AP012978.1|WP_148307651.1|874354_875011_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_148307650.1|873745_874273_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_052199290.1|870904_871198_+|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|225209
NZ_AP012978.1|WP_043107486.1|875247_875925_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	unknown	unknown	gnl|CDD|274750
NZ_AP012978.1|WP_043107499.1|886691_888125_-|sodium:proton-antiporter-NhaD	unknown	unknown	gnl|CDD|129857
NZ_AP012978.1|WP_043107494.1|885087_885765_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_AP012978.1|WP_043107487.1|876812_877589_-|hypothetical-protein	unknown	unknown	gnl|CDD|181442
NZ_AP012978.1|WP_081999807.1|881887_882877_-|alanine--glyoxylate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|223153
NZ_AP012978.1|WP_148307780.1|877585_878464_-|MotA/TolQ/ExbB-proton-channel-family-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043109219.1|880484_881288_-|phosphatidylserine-decarboxylase	unknown	unknown	gnl|CDD|234591
NZ_AP012978.1|WP_148307653.1|882973_883534_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_081999807.1|881887_882877_-|alanine--glyoxylate-aminotransferase-family-protein	gnl|CDD|223153	COG0075, COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism].	5.0386e-139
NZ_AP012978.1|WP_043107490.1|878991_879795_+|ferritin-like-domain-containing-protein	gnl|CDD|377292	pfam04305, DUF455, Protein of unknown function (DUF455).	1.54734e-126
NZ_AP012978.1|WP_043107498.1|886045_886609_-|glycine-zipper-2TM-domain-containing-protein	gnl|CDD|225676	COG3134, COG3134, Predicted outer membrane lipoprotein [Function unknown].	1.86875e-20
NZ_AP012978.1|WP_052199291.1|876120_876816_-|GTP-binding-protein	gnl|CDD|349766	cd03112, CobW-like, cobalamin synthesis protein CobW. The function of this protein family is unknown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterize it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage caused by mitomycin. YijA gene is a homologue of the CobW gene which encodes the cobalamin synthesis protein/P47K.	1.00382e-63
NZ_AP012978.1|WP_052199290.1|870904_871198_+|antibiotic-biosynthesis-monooxygenase	gnl|CDD|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	0.00107535
NZ_AP012978.1|WP_043107486.1|875247_875925_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	gnl|CDD|274750	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ. This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. [Protein synthesis, tRNA and rRNA base modification].	2.93255e-63
NZ_AP012978.1|WP_043107499.1|886691_888125_-|sodium:proton-antiporter-NhaD	gnl|CDD|129857	TIGR00775, CT857_hypothetical_protein, Na+/H+ antiporter, NhaD family. These proteins are members of the NhaD Na+:H+ Antiporter (NhaD) Family (TC 2.A.62). A single member of the NhaD family has been characterized. This protein is the NhaD protein of Vibrio parahaemolyticus which has 12 GES predicted transmembrane regions. It has been shown to catalyze Na+/H+ antiport, but Li+ can also be a substrate. [Transport and binding proteins, Cations and iron carrying compounds].	2.41978e-120
NZ_AP012978.1|WP_043107494.1|885087_885765_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.94585e-85
NZ_AP012978.1|WP_043107487.1|876812_877589_-|hypothetical-protein	gnl|CDD|181442	PRK08476, PRK08476, F0F1 ATP synthase subunit B'; Validated.	0.00384275
NZ_AP012978.1|WP_043107495.1|885766_886030_-|hypothetical-protein	gnl|CDD|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	2.16148e-05
NZ_AP012978.1|WP_043109219.1|880484_881288_-|phosphatidylserine-decarboxylase	gnl|CDD|234591	PRK00044, psd, phosphatidylserine decarboxylase; Reviewed.	5.26425e-151
NZ_AP012978.1|WP_043107493.1|883764_885084_-|two-component-sensor-histidine-kinase	gnl|CDD|182754	PRK10815, PRK10815, two-component system sensor histidine kinase PhoQ.	2.03311e-52

Protein sequences

>NZ_AP012978.1|WP_148307780.1|877585_878464_-|MotA/TolQ/ExbB-proton-channel-family-protein
MFVLIVAAGALVYWKWGLVNAIYFKDQLTELGWVINGAIMVLFLVGMSRMAISLMGYAREEAALTRFVRNLHKRPDEALRGVPKRSLIAQRYRTLLKLHETHTPINQNALASTLVAAESTRSSLAKFVNNILILTGVFGTIVSLSIALIGASDVLENAVSASGMGMVIHGMSTALSTTITAIVCYVFFGYFYLRLNDAQTNLVSAIEQVTTSYLMPRFQVETDTVLYEFTGLIRSLQSLVAEMANSQKAFRETEQQIVETLEHYRGKVDNLEDHMTDILRMLRLGFRLRDDE
>NZ_AP012978.1|WP_043107487.1|876812_877589_-|hypothetical-protein
MNDGFTDLRLNRQEDQVNESFWPSFTDIMTTVVMIFLIALVVLLVRNMELVRQLRATMEAERIAAELARATGEEKDSLSMALHRTEAELRQARLEILHLREKAVDREKVITDQIATINRLTEARDALERKYLVLVGDYDNLKVKYDKLVRPARSPAGRHVVEVRYWKEGGQYRIAWHEGDKGEFQPISRKHLDRVLSRLLKQHPNGLYVKVIFPENSGLSYNEAWEFTNHLHRNYDYYFRDDGKAARDAPRAGVTGGE
>NZ_AP012978.1|WP_052199291.1|876120_876816_-|GTP-binding-protein
MIAVNLITGFLGTGKTTLVRHLLAHHPENETWAVLVNEFGDIGIDGTLLDETGVAIEEVAGGCLCCVAAPAFEVGLNRLIRAHRPERILIEPSGLGHPAQILERLRSPLYREVLRLEATLCLIDPRHLDSPRHLEHPVFRDQIHLADVLIANKADLCDPVQEQAFLDFAATLRPPPARLAVTEQGRIDPSLLYLDASPRTASFPEAHAFLLADEAAPEPAGVSNARRCSTG
>NZ_AP012978.1|WP_171816179.1|875917_876088_-|hypothetical-protein
MHTPEGLLEYNRAGTDAAAVRERETDEQTASRLQLIDPAALEAEALETALRRCLLS
>NZ_AP012978.1|WP_043107486.1|875247_875925_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB
MKILSLDTTEQACSAALLLDDELVERFEIAPRQHSRLLLPMVESLLAEAGLALAQLDALAFARGPGSFTGVRIATAVAQGLALGGDLPVAPVSSLLALAQGAARESGAGQVLALLDARMQEVYVLACVRGEHGLMEPLGAETVGPPAAVSLPGGGDWLLAGSGVAAYGEVLAHLGGTRLPEWQVHAADVARLAVALVRRGETVAAEAALPVYLRDQVAQKMTPLN
>NZ_AP012978.1|WP_148307651.1|874354_875011_+|hypothetical-protein
MDTSYEQSREFVFFVDALKYSFSAADRYYKSVQSSLTELEKSGISQIQENQIVPIISDAWSMIDSAHRIRELIQQAPKLKKNSSEIQVFIRTTKEVEDLRHYVQHLRKGIYSLPEQSTPIWGVLSWVSSTEEKTSFTIISGTPRKDVSVYSCAYDTLNNKFAQKLILSVNNQRVDMFSLNQRIQALLKFVKQWAEKKGYDFGNRKIPVFTFRVQTPSA
>NZ_AP012978.1|WP_148307650.1|873745_874273_+|hypothetical-protein
MFEIIELTLEQSGAYKSIKPMLYGNIFHVTPQHNLASILHDREIRPNDSGNLEGAFGKFRKSYARVRSRVSLFDFHNPPGSEIEKNIYKCLPTSDASADTPLAFLFLAEVYWFNVIPYSSAEFDANSDQQIVPHVEATCLGAIPLEAIDRIIKATFTEDPNSMANILNRSRNNAL
>NZ_AP012978.1|WP_148307649.1|872742_873273_+|hypothetical-protein
MSQNINIKKGLWRLWIVATFIWLLSVAIYHAASISYWAGYHFQFLIGLVETNKTFFQAIEEKKKAKALILSCKLAKRVACDFDLNKSKMRKCMSTEEFKKEFIDNLESSNIIKRDKVKSINDEIDNSEIAGICEDMLNIHIPEINTLFLVTILMVPLSALVIYFIVLWFLRGFIKN
>NZ_AP012978.1|WP_148307648.1|871633_872005_+|hypothetical-protein
MNNVIRIFSMLLVLIVSAPNAFAEIKLSNALVKDIGRAYGFYLGQNYSLSEISKTYPSLSGLALIAQEEFSVAFKSSIDGMDALMAKYGKSEWNKIKKNSPNKLQILSILNKYQKRKLVSLLD
>NZ_AP012978.1|WP_052199290.1|870904_871198_+|antibiotic-biosynthesis-monooxygenase
MYAVIFKAEINELDESYSEMASLMRELAINKYGCTEFTSVTEEKQEIAISYWESQEQIKKWKQDAEHLVAQEFGASKWYKSYQVQVVKIVREYSKNT
>NZ_AP012978.1|WP_043107490.1|878991_879795_+|ferritin-like-domain-containing-protein
MPRNLHAAAHECLLTADIDSKLEQARALDAEWRAGRLHCASVVLPDVTEPGRPARPELVPPSQVPQRRIGTPEGHAALIHAVAHIEFNAINLACDAAWRFQGLPEAYYADWLRVAAEEAHHFTLLRDRLRALGYDYGDFAAHDGLWELARKTADDPLRRMALVPRVMEARGLDVTPGMMKRFAHIGDTETVAILEVILRDEVGHVEAGTRWFRHLCRERGLEPEKHYFELLEAAFGERMRCPLHKAARRQAGFSETELQRLEAMCKD
>NZ_AP012978.1|WP_052199292.1|879782_880475_+|hypothetical-protein
MQRLIPWLLLLAVTSASAEPAALLVYKVWEQGSDPYISRVLVTPTHVRLDEGQDTGDYTLLDRAAGVVYNVSAEDHSVLVMAPGEASPPAQPALMLDATDEPDTQAPKVAGRTPHRVELLANGERCTTLTVLPGAMEAALAGLRDLRRVLARVQARSLAAMPQDLQTACELASTVYAPTRSLDHGLPLSEQSPGRVQVLLDYMPDFEVDGGLFGVPSGYQRIEMSELVPG
>NZ_AP012978.1|WP_043109219.1|880484_881288_-|phosphatidylserine-decarboxylase
MLPQHLLSRGMYHLARSETGWLKDLLIRYVVTRYDVDMQEALVEDPYAYPSFNAFFTRALKPGVRPLTQEGMASPVDGKVSQAGRIRHDRLIQAKGHEYSLYALLAGDGFMASQFESGTFATIYLAPRDYHRIHMPLDGTLREMVFVPGDLFSVSETTAELVPGLFARNERVILLFDTDRGPMALVLVGAIFVGSMETVWHGEVRSPDDGIARWTYEGDGAPHFSRGEEIARFNMGSTVIVLNTQHAVDPVNGLVGRRVRMGEKIAD
>NZ_AP012978.1|WP_081999807.1|881887_882877_-|alanine--glyoxylate-aminotransferase-family-protein
MSQTAFHPPLRTLMGPGPSDVPPRILEALSRPTIGHLDPAFVDLMDEIKALLQYAFQTENQLTMPISAPGSAGMEACFVNLVEPGDKVIVCQNGVFGGRMKENVERCGGEAVMVMDDWGKPVDPQKVEDALKAHPDARILAFVHAETSTGALSDAKTLAELARRHDCLTIVDAVTSLGGCELRVDDWGIDAVYSGTQKCLSCVPGISPVSFSERAQHVIANRGHKVQSWFLDMNLIMAYWGGSAKRAYHHTAPVNAMYALHEALLMLKKEGLENAWARHRENHHILRTGLEAMGLEFIVPEDARLPQLNAVSIPAGADDAATPGRDACR
>NZ_AP012978.1|WP_148307653.1|882973_883534_-|hypothetical-protein
MSMALETPSPAPTGETQTEEPLIRIGEHWVPAHEAWQKLETATAVTEIIDRFNQRFPELSTPVTREVVPLVRQRLKAIALRMPQRQVIRELGAVATELLHRHRPEEALAILREQHDQDIDLVGLVALAGEGPYLDALRKEAREYTANKILPEQTAAIWNDMHRPAPGGGLWNRRKVEMLLQMPTGD
>NZ_AP012978.1|WP_043107493.1|883764_885084_-|two-component-sensor-histidine-kinase
MQPSITRRLLLVSTALVAAFAGLAGWSLDSAFRHASETALVEQLQAHVYTLLATAREDDHGRPRLPQTLPDPAFNRPDSGRYARVVGEDGRYRWQSASLIGRELPESEPPAVGERRIGHHGDLLLLEQTVAWEDLAGTPIPYTLTIAADTADLERQQADFRATLWGWLALLSLILLGVQLAAVRWGLRPLYRLAGAIKQIEQGRASRLPDGVPVELRPLTDNLEALLSQAQARQERVRHSLADLAHSLKTPLTVLRGATDPERCPELSALVEEQVQRIDEIVSYQRQRAAVAGGTALSAPVALRPLIERLGRGLAKLHADRGIRLSIDLDDSVCLRMDEGDLMELFGNLLENAFRHAREQVRVCRLEGSSLTLEIADDGPGLPPGMGEALLARGVRADERHPGEGIGLAVVREILQQYGASIRIGHSALGGASFVLTFP
>NZ_AP012978.1|WP_043107494.1|885087_885765_-|response-regulator-transcription-factor
MRILLVEDEDPLREQLARELSQRGFPVDAAPDGEEGLFLGREYPMDLAIIDLGLPKLSGIELIRRLRELERTFPILILTARDSWQDKVEGLEAGADDYLTKPFHVEELVARVKALLRRAAGHASPVIEGCGIRLDTARQTVAVDGRPVELTGHEYRVLEYLMLHAGKVISKTELTEHLYDQDFDRDSNVLEVFIGRLRRKLDPEGQRKPIETLRGRGYRFRTDID
>NZ_AP012978.1|WP_043107495.1|885766_886030_-|hypothetical-protein
MRTIACVLLMLAATTGQAGWWQHASLDEAVSEARERFDGRVISAETLFDKHGRETYSIRILTPDGRVKRYRVRAGEERRRRHRDDRH
>NZ_AP012978.1|WP_043107498.1|886045_886609_-|glycine-zipper-2TM-domain-containing-protein
MNKLIQITTLALGIALTGCATASPHWDDDHDEYRHRGPFEDTARVIRVTPIYETVRVSVPEERCWKERYYQRSDYGHDDSYTPPIVGAIVGGVVGNQFGRGSGKTAMTVAGSLLGASIARDLNHGDRHVDYRPRHRRRCEVTDRVEEHEEIVAYRVKYRYKGRVFHTRMNHHPGKHIRVRVDVRPID
>NZ_AP012978.1|WP_043107499.1|886691_888125_-|sodium:proton-antiporter-NhaD
MYHRPRITVGLLLLAATLLPALSFAAETLAATRDLTATTTGLAALGIFVLAYLLVMAEEFTHLRKSKPVILAAGVIWAMIALAYRDTGDSHIVEAAVRHNLLEYAELMLFLLVAMTYINAMDERNVFAALRSWLIKKGFSLRQLFWITDLLAFFISPVADNLTTALLMCAVVLAVGGNNPRFVLVACINIVVAANAGGAFSPFGDITTLMVWQKNIHTPEGVIDFWAFFSLFVPALVNWFVPALLMSLTVSREKPDTDEAPVRMQFGGGIIIGLFLATIVTAVSFHSLLQLPPVVGMLTGLSYLQFFGFYIKMRERQGRPDQNGAIGSPVAFDVFRHVARAEWDTLLFFYGVVVCVGGLGFIGYLTLVSQVMYTGWGPTEANITVGLLSSVIDNIPVMFAVLTMLPDMSEGQWMLVTLTAGVGGSLLSIGSAAGVALMGQARGVYTFFGHLKWTPVIALGYAASIAVHFWINAHLFD

Crispr_ID: NZ_AP012978_6

• CRISPR_ID: NZ_AP012978_6
• CRISPR_location: 961821-961899
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP012978_6

Consensus_repeat	Method
TTCGTGGCGGGGACGCCGCTCCCAC	CRISPRCasFinder

spacers of NZ_AP012978_6

>6.1|961846|29|NZ_AP012978|CRISPRCasFinder
GGGTAGGAGGCCTGTCCCCGGGCCGAACA

CRISPR arrays and Neighbor proteins around NZ_AP012978_6

CRISPR arrays

The CRISPR arrays of NZ_AP012978_6

>merge|NZ_AP012978|6|961821-961899|CRISPRCasFinder
TTCGTGGCGGGGACGCCGCTCCCACGGGTAGGAGGCCTGTCCCCGGGCCGAACATTCGCGGCGGGGACGCCGCTCCCAC

>NZ_AP012978|6|5|961821-961899|CRISPRCasFinder
TTCGTGGCGGGGACGCCGCTCCCAC	GGGTAGGAGGCCTGTCCCCGGGCCGAACA
TTCGCGGCGGGGACGCCGCTCCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_043107571.1|965740_967177_-|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|182606
NZ_AP012978.1|WP_043107570.1|963226_964840_+|hypothetical-protein	unknown	unknown	gnl|CDD|273971
NZ_AP012978.1|WP_081999816.1|959136_960147_-|EF-P-beta-lysylation-protein-EpmB	unknown	unknown	gnl|CDD|163533
NZ_AP012978.1|WP_043107569.1|960762_961749_+|EF-P-lysine-aminoacylase-GenX	unknown	unknown	gnl|CDD|273090
NZ_AP012978.1|WP_043107572.1|967337_967682_+|sulfurtransferase	unknown	unknown	gnl|CDD|238786
NZ_AP012978.1|WP_043107563.1|953861_954185_+|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NZ_AP012978.1|WP_052199301.1|964862_965471_+|YdbL-family-protein	unknown	unknown	gnl|CDD|377762
NZ_AP012978.1|WP_043107561.1|952124_952928_+|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NZ_AP012978.1|WP_043107562.1|952947_953583_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|222854
NZ_AP012978.1|WP_171816182.1|954917_956954_-|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|376350
NZ_AP012978.1|WP_043107560.1|947364_951399_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NZ_AP012978.1|WP_043107575.1|968650_969403_-|porin	unknown	unknown	gnl|CDD|367457
NZ_AP012978.1|WP_171816183.1|969293_969875_-|outer-membrane-protein-transport-protein	unknown	unknown	gnl|CDD|224978
NZ_AP012978.1|WP_043107568.1|960181_960754_+|elongation-factor-P	unknown	unknown	gnl|CDD|234788
NZ_AP012978.1|WP_043107564.1|954389_954887_+|hypothetical-protein	unknown	unknown	gnl|CDD|377605
NZ_AP012978.1|WP_043107573.1|967778_968009_+|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl|CDD|238180
NZ_AP012978.1|WP_043107574.1|968051_968531_+|DsrE/DsrF/DrsH-like-family-protein	unknown	unknown	gnl|CDD|379334
NZ_AP012978.1|WP_043107576.1|970100_971012_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176112
NZ_AP012978.1|WP_043109236.1|962011_962740_-|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl|CDD|235420
NZ_AP012978.1|WP_043107566.1|957074_958994_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_043107571.1|965740_967177_-|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|182606	PRK10637, cysG, siroheme synthase CysG.	0
NZ_AP012978.1|WP_043107570.1|963226_964840_+|hypothetical-protein	gnl|CDD|273971	TIGR02099, probable_transmembrane_protein, TIGR02099 family protein. This model describes a family of long proteins, over 1250 amino acids in length and present in the Proteobacteria. The degree of sequence similarity is low between sequences from different genera. Apparent membrane-spanning regions at the N-terminus and C-terminus suggest the protein is inserted into (or exported through) the membrane. [Hypothetical proteins, Conserved].	0.000140449
NZ_AP012978.1|WP_081999816.1|959136_960147_-|EF-P-beta-lysylation-protein-EpmB	gnl|CDD|163533	TIGR03821, EFP_modif_epmB, EF-P beta-lysylation protein EpmB. Members of this radical SAM protein subfamily, including yjeK in E. coli, form a distinctive clade, homologous to lysine-2,3-aminomutase of Bacillus, Clostridium, and methanogenic archaea. Members of this family are found in E. coli, Buchnera, Yersinia, etc. The gene symbol is now reassigned as EpmB (Elongation factor P Modification B). [Protein fate, Protein modification and repair].	5.85223e-159
NZ_AP012978.1|WP_043107569.1|960762_961749_+|EF-P-lysine-aminoacylase-GenX	gnl|CDD|273090	TIGR00462, genX, EF-P lysine aminoacylase GenX. Many Gram-negative bacteria have a protein closely homologous to the C-terminal region of lysyl-tRNA synthetase (LysS). Multiple sequence alignment of these proteins with the homologous regions of collected LysS proteins shows that these proteins form a distinct set rather than just similar truncations of LysS. The protein is termed GenX after its designation in E. coli. Interestingly, genX often is located near a homolog of lysine-2,3-aminomutase. Its function is unknown. [Unknown function, General].	1.9655e-147
NZ_AP012978.1|WP_043107572.1|967337_967682_+|sulfurtransferase	gnl|CDD|238786	cd01528, RHOD_2, Member of the Rhodanese Homology Domain superfamily, subgroup 2. Subgroup 2 includes uncharacterized putative rhodanese-related domains.	1.28004e-26
NZ_AP012978.1|WP_043107563.1|953861_954185_+|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.23818e-05
NZ_AP012978.1|WP_052199301.1|964862_965471_+|YdbL-family-protein	gnl|CDD|377762	pfam07027, DUF1318, Protein of unknown function (DUF1318). This family consists of several bacterial proteins of around 100 residues in length and is often known as YdbL. The function of this family is unknown.	1.83496e-22
NZ_AP012978.1|WP_043107561.1|952124_952928_+|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	5.48631e-09
NZ_AP012978.1|WP_043107562.1|952947_953583_+|AAA-family-ATPase	gnl|CDD|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	9.18837e-25
NZ_AP012978.1|WP_171816182.1|954917_956954_-|EAL-domain-containing-protein	gnl|CDD|376350	pfam00563, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.	3.41755e-37
NZ_AP012978.1|WP_043107560.1|947364_951399_+|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_AP012978.1|WP_043107575.1|968650_969403_-|porin	gnl|CDD|367457	pfam03349, Toluene_X, Outer membrane protein transport protein (OMPP1/FadL/TodX). This family includes TodX from Pseudomonas putida F1 and TbuX from Ralstonia pickettii PKO1. These are membrane proteins of uncertain function that are involved in toluene catabolism. Related proteins involved in the degradation of similar aromatic hydrocarbons are also in this family, such as CymD. This family also includes FadL involved in translocation of long-chain fatty acids across the outer membrane. It is also a receptor for the bacteriophage T2.	1.43374e-29
NZ_AP012978.1|WP_171816183.1|969293_969875_-|outer-membrane-protein-transport-protein	gnl|CDD|224978	COG2067, FadL, Long-chain fatty acid transport protein [Lipid metabolism].	1.11123e-13
NZ_AP012978.1|WP_043107568.1|960181_960754_+|elongation-factor-P	gnl|CDD|234788	PRK00529, PRK00529, elongation factor P; Validated.	3.84175e-119
NZ_AP012978.1|WP_043107564.1|954389_954887_+|hypothetical-protein	gnl|CDD|377605	pfam06103, DUF948, Bacterial protein of unknown function (DUF948). This family consists of bacterial sequences several of which are thought to be general stress proteins.	0.00651881
NZ_AP012978.1|WP_043107573.1|967778_968009_+|sulfurtransferase-TusA-family-protein	gnl|CDD|238180	cd00291, SirA_YedF_YeeD, SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.	4.72696e-29
NZ_AP012978.1|WP_043107574.1|968051_968531_+|DsrE/DsrF/DrsH-like-family-protein	gnl|CDD|379334	pfam13686, DrsE_2, DsrE/DsrF/DrsH-like family. DsrE is a small soluble protein involved in intracellular sulfur reduction. The family also includes YrkE proteins.	2.32067e-59
NZ_AP012978.1|WP_043107576.1|970100_971012_+|LysR-family-transcriptional-regulator	gnl|CDD|176112	cd08420, PBP2_CysL_like, C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold. CysL, also known as YwfK, is a regular of sulfur metabolism in Bacillus subtilis. Sulfur is required for the synthesis of proteins and essential cofactors in all living organism. Sulfur can be assimilated either from inorganic sources (sulfate and thiosulfate), or from organic sources (sulfate esters, sulfamates, and sulfonates). CysL activates the transcription of the cysJI operon encoding sulfite reductase, which reduces sulfite to sulfide. Both cysL mutant and cysJI mutant are unable to grow using sulfate or sulfite as the sulfur source. Like other LysR-type regulators, CysL also negatively regulates its own transcription. In Escherichia coli, three LysR-type activators are involved in the regulation of sulfur metabolism: CysB, Cbl and MetR. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.78196e-85
NZ_AP012978.1|WP_043109236.1|962011_962740_-|UDP-2,3-diacylglucosamine-diphosphatase	gnl|CDD|235420	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional.	1.43342e-98

Protein sequences

>NZ_AP012978.1|WP_043107569.1|960762_961749_+|EF-P-lysine-aminoacylase-GenX
MDRRRHVDDWRPGASLETLRARARLLARIRAFFAARGVLEVETPLAGISFGTDPAIEPLRSRFTGPGHARGLDLYLQSSPEFFMKRLLAAGSGPIWQLGKAFRNGEAGPRHNPEFTLLEWYRPGFDDTALMDEVAALVRVALDQDLPAEHWSYAALSRTHLGIDPLEADTENLRNCALAHDVLGAEGLVLDRDGWLDLLMSTLIEPLLGRDGLTFVTDYPASQASLARLAPDGRTAARFELYWQGMELANGFHELNDAAEQAQRFEQENCRRRSTGQDPMPVDDALLAALEHGLPDCAGVALGIDRLLMCQLGLDDIDQVLAFSLARL
>NZ_AP012978.1|WP_043107568.1|960181_960754_+|elongation-factor-P
MASYNTNEFRSGLKLMLDGDPCVIIENEFVKPGKGQAFNRVKLRNLKTGRVLEKTFKSGESVEAADVMERDLAYLYTDGEFWYFMDNETYEQYQADANAMGEAVKWIKEQDVCNVTLWNGQPIVVEAPNFVVLEITETDPGLKGDTSGGGGKPATLETGAVVRVPLFVQTGEKIKVDTRSGEYVSRAKDD
>NZ_AP012978.1|WP_081999816.1|959136_960147_-|EF-P-beta-lysylation-protein-EpmB
MITSAPAPSQPEDWQRELARAVSDPAELLRLLELPDSLLAGAQRAAATFPLRVTRHYLGLIRRGDPGDPLLRQVLPLDEERHPAPGFVTDPVGDSAAALGDGLIHKYHGRALLVVTGACAIHCRYCFRRHYPYAEDSALRDPAAVLARLRKMPEIREVILSGGDPLSLSDGRLQVLLDGLEELPQLRRLRIHSRLPLVLPERLTGRLVSRLAASRLGVSLVLHANHPRELAPALRPGLRALREAGVTLLNQSVLLRGVNDEAATLAELSEALFDHGVLPYYLHLLDPVAGSAHFAVSSDEAGALHRQLCAQLPGYLLPRLVREVPGEPSKRPMEAP
>NZ_AP012978.1|WP_043107566.1|957074_958994_-|hypothetical-protein
MDNETLTRTDERTGTASTLGLVVPEQSPAPENSMLLEPRDTAEWIASLPLANIGETSRQVYTTLLDFNRYEIPDLVRAKVVELFRPTVDYVCHNLRRHYIDVGFPLSKKAWKTVVLARELNNELATSYKIIVERMLSGATERFDRKLLVIALHRTLHYLGRVYLQACLAYTRPPAQLWKQVNAVYAFSRQNHIHRIPVKMKMEDIEEVSTIEERYKALLLFAATVPSRLRQSHLEITFQKTLEWSGQTHFLGMDDDIPANGALNVSLTSDEGPIHNALRMPIASRHVAILDVRPLIQRLHAEYEEAPLDGSGDIRPGKPLISRALLRQLIRSWHAPAERQFVRTRLHFSLHVLTGFRSIHAALSPSPLPPSPSEELPSTFNSSPNINIPALTSAHQIDPLGAIDDSQLSLAPTSLDLQSGTSLVNENSSFLLNGNPLADKPGTPAEWQESRMIDPLDPKGMEVTTLNESAGGYCIQWLAKDHPPKVKVGQLLGVGSKDNPLDYSLAVIRWMHSISQERLELGMEVISTHVRATHARPLNSGKSSRKALEKIPCFILDFHHPPRGNEEPSLVFNSTSYPTGSQFVLEDLPGDRQVIRLTRLIDFSSAFARLGFELVASGEDSEGQSSKPYNEFDSLWNSL
>NZ_AP012978.1|WP_171816182.1|954917_956954_-|EAL-domain-containing-protein
MIGSSAEDASRCANALRNSGQPVRMESTETREGLLRLLETEPADLVTINADSATLPPDIAIEMIREENPAASIILLSENPPAWAEYARENGVRDLLHSISIGRLVFAIQREYHTLLLRQELAHTRHRLANAELRFQKLLKSSRDAIAYIHQGLHIQSNAVYRELFGLSAEDMESITMMDLVAPEDRNTFKRLLRQAGEKEVRKKLRCRHRDGGEFEADIELHPLEVNDEPCLQVLIRTDSTNGELQARIRQLIDRDPHTQLFNRHAFVGALERIQTTGGFRDNAMLMEISIDNFAELCDREGIDKGDRLLKKTAEILRSHFSDDLLSRFGDHEFLVLTHSRKSPDEVAERCLDTLHQGSIQEACELAEPPEFSLGAITSSQASNLSALELIRRCRRAARYARTERDPASEPISVFNDIDLEEPVVPEVDTEIVGLIDGALEHDGFRLLYQPIVSLEGDTRENYSVFVRLIDENDVEREPAWFYQHANRSERLSEIDRWVIRRAISELSRHRSIGRKINFHITLSHDGALDDSMLLWVCDCLREFKAKGAWLYFQFDLELLQQRPPGLMRLIEGLKKINCQISCNGIKDGFTNYDLLQHYHVELVRLSPELTRDLPSDVKRQERLAELNAGLQQAGMKTAATGIEDANTLATLWSMNINYIQGYFLQEPAPQIDVVGNE
>NZ_AP012978.1|WP_043107564.1|954389_954887_+|hypothetical-protein
MSEQESEAPKAISHEDEYARLSEVFESSARRWELIIYPSLFAFIVLALYGFYLIYNLQRDVHYLAISVDRNMTTLAGNMQVVAKNMGQLTTNVRAMTVSLDSIDHKVSTLEPMLANIHSMDQSMRDMTRTTGALNAAAQGMNLHMYRMNRDLGRPMRIMNAFMPW
>NZ_AP012978.1|WP_043107563.1|953861_954185_+|hypothetical-protein
MRPFGEDENRLPADALLKRARNAFWDGQPQKAEVLYLRYLQMRPDDVNGFGELGNLYQSMGRTRDALDAYYEAGVRLRAEGDRKQLARIVEWLEKASDPRARELSAQ
>NZ_AP012978.1|WP_043107562.1|952947_953583_+|AAA-family-ATPase
MITMIGSLKGGSGKSTVTFNLAIWLKLADSEVAVVDADPQATLSDVLMVRAEEDYHPTAPRLKADVLKSPEALGEYEQVLIDVGTASMDNLKQAIAVADRILVPVPPSQADIWSTQRFLRFVAANAGDRDIEVLGFINRADTHHAIRESDEAAAALISLPGIRYLKPRLAQRTVYRRSFSEGLAVFEQQPRGKGAAEWNALAAALYPDLLG
>NZ_AP012978.1|WP_043107561.1|952124_952928_+|hypothetical-protein
MKVECIRKLFLPCLVSLVSMQVTLAAETTQWRPDAAQPPAPPQAPVAPLPPPPPVQPRFRPVPAAAWQPSRPMTPYPGQPFVNMGIPPAPPPPVVPAFARQYAWRPVSPPLIAPRPAHAWMPPGAAWARGYRPAPPPPPRYRPLPPPRPAFPMTGPVPRAPYAYPPLGYYPPPYPGVPFRGALGQPYPMSFWPGPYPPPGPALTLTPWGVMPAGNGWSDPYFTRRWPGPVYRRLGVGSRRSSWGGFLPGWMPLAGTPWGGDCFWCGS
>NZ_AP012978.1|WP_043107560.1|947364_951399_+|efflux-RND-transporter-permease-subunit
MSEIDTKPDWEAGVQVEEHSLGIAGAITRFFINSPLSPLLYIAMLGLGILGLMITPRQEDPQISVPMIDLFVQYPGADVDQVVALAVQPLERLMYEIDGVKHVYSAAERGRGVVTVQFEVGEDMAPSLVKVNDKLASNRDRIPPGVLPPLVKAKGIDDVPVVTITLWSEKDYNQDGMPDVDDSQLRRLAQSVLQHLNEIHETGNSFVVGGRAEQVIVEVYPERLAGFGLSLGQVAQAIRAANMEQQMGNVEAGGSRLLVVSGAFLKTVDDIRELQVGVHSGVPVYVHDVADVRQGPEDARQLVAFYSGAASGDLDRAVAVPAVTIAVAKKKGTNGVKVANEVIARVNSLKGTLIPNDVNVTITRNYGKTANDKVNALIKKLFIATAIVFALVWLAFKALNPAIVVLMVIPVVLLFTILCAWLLGFTIDRVSLFALIFSIGILVDDAIVVVENIYRRWLEAGTTDMATAVDAVREVGNPTILATGTVIGALLPMGFVSGMMGPYMLPIPVLGSVAMAVSLFAAFVFTPWLAIHGRLRPTMDYLEKAEKREHKEAEWLDGLFRRILIPMIRSPRRARLFKLGMWGAFFLACSLFYFKWVAVKMLPLDNKPEFSVVLNMPEGTALAVTGNMAHRIADRLRRMPEVVDAQIYVGTARPFDFNGMVRHYYLRNQPWQAEIQLELLDKHERERSSHEIAVDAREQVRKLVEGSGATFAVVEMPPGPPVLQSVVAEVHGPDGDTRRAVATMLTDVFRQTENLVDVDNYMREPYDYWHFEIDYEKAQRRGITVETINRELAMALGGYVLGDVKQRAGHEPINIVIQIPLAERSNVSRLGDILVALPDGKGVSLRELGHFVRKVESHIAYHKDLRPVEYVVADVGGKLAAPIYGMLEVQDKLQELGCDTPDGVRLCDHIYWTGPPPTDEHSAFEWAGEWTVTYETFRDMGLAFIAALGLIYILVVWEFGNFRIPALIMAPIPLTLLGIIPAHMLFFQMGWGGEFTATSMVGWIALAGIIVRNSILLVDFSVHRLHAGVGVVEAVISACKTRTRPILITALALVGGSSVIFFDPIFQGMAISLASGVLVSTILTLIVIPLGCVKAADALCEVANVDCAGQGLLPEQTHPLEEEPAAGPPLWMRLWGGLMTAVFAMVGVIASVWGWIAERRARKTTSAPVTGKGDERAPAPVDAPVAERPETTSPAADTSAAEAKSGSEKAVEDASPAQFSAADEPAEAVNGLSTGGPVDAPPAPAEPSPAEKTADAPDADAEQAEEKAAVRHTATRKTTAKKAAAKKTVAKKAASKKVSVKKQDGDASPASPQPGEKEGKTENARTRRGIRLKAPDNLSDDGLG
>NZ_AP012978.1|WP_043109236.1|962011_962740_-|UDP-2,3-diacylglucosamine-diphosphatase
MAEQIFISDLHLAEERPETLALFERFLHERPRPGDRLYILGDLFDAWIGDDDDAPLACRVREALAATSARGVQLLMQRGNRDFLMGRRLMQAIGATLLPDPFLTEVAGEPTLLMHGDLLCTDDVAYQKARRRLRNPLFQWLAMRRSLAWRRARAAEYRRRSGEVTAMTPADIMDANADTVLNYLHRHHATRLIHGHTHRPAVHEHRLPDGRIAYRHVLDEWHADHAAAWVADEVSLRREEIR
>NZ_AP012978.1|WP_043107570.1|963226_964840_+|hypothetical-protein
MEGRWSLRVRLRRLDPARLPPLVAALGNLGLEGLGGRIRGRLHLEGGAGGVDRLGFEGRFEDLAWSDAPGEQAAEGVRGEVSLALRRAEPSWRGRLALTLDGGELYSDSLFFDLNKRPLVLDARGGWRPGRLTLDTLQLDDGQALRLSGAATLALAPFGLLRADLAAESADLAALHARWGQPWVLDTPFEGVTAAGSGQAHLHWHQGRARALDLTLSGLRIDGETPFAIDRLDGELHWRAEGVAPDSHLRLGGFRLGRLAFGATEVAFNTSGRMAYLRRPLVIPFHEGKLRIPEATWVQTDEGAEGGFSLRLHEVSLASLTEALAWPRMEGRVNAEIPRARYRAGTLKVGGDVVIQAFDGRIVIGDLALAEIGSAAPVLTGRLRLHRLDLLPLTRTFSFGDIQGRLDGEIEDLRLVARQPDRFEARFFTSPDDDRPHRISQRAVENLTELGNGVSGVPSTGFLSLFKTFGYDRIELRIRQRGDHAWIDGIPAGKGGYYLVKGAGIPRIDVIGRNREVAWNDLVARLRSIRVEGMQMR
>NZ_AP012978.1|WP_052199301.1|964862_965471_+|YdbL-family-protein
MNKRAILTWPVLALLLASCVTINIYFPAAAAEEAARTIVRDVLGKGDKQETAPAEKPQSQLAPDWPARLALGLLDALVPPAEAAAQPDIDISSPAISRLRQGMAQRQRQLAPFYQAGAIGFDRNGLVAIRDLKAVSLRERTRLKKLVAAENRARNALYREIARANGHPEWEPQIRAIFARVWAEEARPGWWFQDGQGNWRQR
>NZ_AP012978.1|WP_043107571.1|965740_967177_-|uroporphyrinogen-III-C-methyltransferase
MQHLPIFFDVNQQPCTVIGGGEIATRKVALLRRAGARVQVVAPELCPALSRMAENGEIEHQARPYQESDLDEAVLVIAATNDLALNRQIARAARARRIPVNVVDNPTDGNFIMPSIIDRSPVVAAVSTGGASPVLARLIRARLESLIPAGYGRLAELAARFRDRVKQTIADPDERRRFWDRILQGGVAERVFSGHMAEAEVLMERELDERQPENGMGEVYLVGGGPGDPDLLTFRALRLMQQADVVVYDRLVAKAVLNMTRHDARRIYVGKERDNHAMRQEEINQLLAYLAKQGHRVLRLKGGDPFIFGRGGEEIDTLAEQGVPFQVVPGITAASGCASYAGIPLTHRDYAQSVTFVTGHLKDNTMNLNWAQLAQPAQTVVFYMGLKGLPVISRELQAHGLPGDTPAALVQQGTTHQQRVFTSTLAELPVLAEREQPKPPTLIIVGEVVQLHEKLSWFRAPEHSEQGATTPVEPGTAL
>NZ_AP012978.1|WP_043107572.1|967337_967682_+|sulfurtransferase
MLVKEIDATELASRLQAGDDVVLLDIRSDAEVAQGVIPGSEHLAMHLIPLKLQDLPRDRDIVLYCRSGARSYHACNFLLQQGVDNVLNLRGGIIGWARQGYEIAAPRQAQAGGF
>NZ_AP012978.1|WP_043107573.1|967778_968009_+|sulfurtransferase-TusA-family-protein
MANFDEELDASGLNCPLPILRAKKALAGMESGKVLRIIATDPGSVKDFEAFAKQTGNELLESGEEGGKFVFLIKKA
>NZ_AP012978.1|WP_043107574.1|968051_968531_+|DsrE/DsrF/DrsH-like-family-protein
MEEKKLAIIATKGTLDWAYPPFILASTAAALGYETEIFFTFYGLQLLKKDLDLKVSPLGNPGMPMPMGMDKWFPTILTALPGMEAVMTAMMKKKMADKGVASLEELRELCQEAEVRLIACQMTVDLFDMDTKDFIDGIEYAGAARFFEFAGESDICLYI
>NZ_AP012978.1|WP_043107575.1|968650_969403_-|porin
MAFKVGSSTAVAVGIDYYWARKIAFDTASLQNKGDGDGWGWNISASHLNGPWSFGASFRSHAEADISGSTTAGGLTFGGTRTTLDIPWRAQIGVRYQVNPELAVEADVTRTGWSSFDILRISHNHPGVPINPIVSENHWKDVNAYRLGATYQLTSDTELRFGYSFDKGAMPDAYFSARTADADRNLFSIGIGRQLGDGLAIEAGYMYVKFKDRSLRSTTLPTTDPNGTLAYNGNYKTTVHLFGAGLSKRF
>NZ_AP012978.1|WP_171816183.1|969293_969875_-|outer-membrane-protein-transport-protein
MACKLRRGVLAGAILGLLGTTGAQASGFNIPEISIGGLGTANAVVANPRMLGAVPYNPSLAAFHSGTTLSGGLMVVHAESEVTTAPPNTPTTASFQGRDNVFIPNLSLTHQISDGITLAFNTSVPLGLSTQYPVGTFPPWHQLTHQESGRGRRHLSQHGVQGWLLHRRRCRYRLLLGTQDRFRYRLVAEQGRR
>NZ_AP012978.1|WP_043107576.1|970100_971012_+|LysR-family-transcriptional-regulator
MADRRLQVFHTVARLLSFTKAAETLHMTQPAVTFQVRQLEEYFNTRLFDRTHNRISLTEAGEVVYRFADRIFELYAEMENAVREMTGEISGSLTIGASTTIAEYMLPALLGDFRNQYPDVTIHLKVSNTEGIVSMVENNTIDLGVVEAPVGNKNLVVDKCRDDCLVAIVPPNHELASRKKVSMEELLKYPFICREEGSGTREVITNYTCKTDECRQAMQVAMELGSPEAVKGAVEAGMGISVVSNATIQKELRLGTLVAIRLDPPLERPFSFVHQKQKFRVRVMEELLEFARPYCHAHQDDEV

Crispr_ID: NZ_AP012978_7

• CRISPR_ID: NZ_AP012978_7
• CRISPR_location: 1002768-1002847
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP012978_7

Consensus_repeat	Method
GAACCGTTCGCGGCGGGGACGCCGC	CRISPRCasFinder

spacers of NZ_AP012978_7

>7.1|1002793|30|NZ_AP012978|CRISPRCasFinder
TCCTGCCTGTAGGAGGTCCGTCGCCGGGCT

CRISPR arrays and Neighbor proteins around NZ_AP012978_7

CRISPR arrays

The CRISPR arrays of NZ_AP012978_7

>merge|NZ_AP012978|7|1002768-1002847|CRISPRCasFinder
GAACCGTTCGCGGCGGGGACGCCGCTCCTGCCTGTAGGAGGTCCGTCGCCGGGCTGAACCGTTTGCGGCGGGGACGCCGC

>NZ_AP012978|7|6|1002768-1002847|CRISPRCasFinder
GAACCGTTCGCGGCGGGGACGCCGC	TCCTGCCTGTAGGAGGTCCGTCGCCGGGCT
GAACCGTTTGCGGCGGGGACGCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_043107600.1|1007264_1007588_-|ferredoxin-family-protein	unknown	unknown	gnl|CDD|378771
NZ_AP012978.1|WP_043107595.1|1001390_1002719_+|tRNA-5-hydroxyuridine-modification-protein-YegQ	unknown	unknown	gnl|CDD|237969
NZ_AP012978.1|WP_052199307.1|1006481_1007234_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NZ_AP012978.1|WP_171816185.1|998657_999896_-|diguanylate-cyclase	unknown	unknown	gnl|CDD|143635
NZ_AP012978.1|WP_081999821.1|1007713_1008160_-|hemerythrin-domain-containing-protein	unknown	unknown	gnl|CDD|179353
NZ_AP012978.1|WP_043107598.1|1004706_1005615_+|site-specific-tyrosine-recombinase-XerD	unknown	unknown	gnl|CDD|234713
NZ_AP012978.1|WP_043107589.1|991990_992572_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043107588.1|990942_991857_+|hypothetical-protein	unknown	unknown	gnl|CDD|366517
NZ_AP012978.1|WP_043107597.1|1003917_1004361_-|YcgN-family-cysteine-cluster-protein	unknown	unknown	gnl|CDD|235356
NZ_AP012978.1|WP_043107593.1|997683_998676_+|dimethyl-sulfoxide-reductase-anchor-subunit	unknown	unknown	gnl|CDD|113736
NZ_AP012978.1|WP_043107596.1|1002913_1003921_-|DUF3549-family-protein	unknown	unknown	gnl|CDD|378801
NZ_AP012978.1|WP_052199306.1|992587_993142_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043107601.1|1008296_1011119_-|valine--tRNA-ligase	unknown	unknown	gnl|CDD|235582
NZ_AP012978.1|WP_043107591.1|993850_996757_+|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|239164
NZ_AP012978.1|WP_043107603.1|1011891_1012554_+|HupE/UreJ-family-protein	unknown	unknown	gnl|CDD|368209
NZ_AP012978.1|WP_148307664.1|993197_993653_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043107587.1|988790_990677_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|236861
NZ_AP012978.1|WP_043107592.1|996779_997502_+|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|319873
NZ_AP012978.1|WP_043107599.1|1005722_1006442_+|DsbC-family-protein	unknown	unknown	gnl|CDD|239318
NZ_AP012978.1|WP_043107602.1|1011319_1011895_+|HupE/UreJ-family-protein	unknown	unknown	gnl|CDD|368209

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_043107600.1|1007264_1007588_-|ferredoxin-family-protein	gnl|CDD|378771	pfam11953, DUF3470, Domain of unknown function (DUF3470). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 50 amino acids in length. This domain is found associated with pfam00037. This domain has a single completely conserved residue N that may be functionally important.	1.1377e-21
NZ_AP012978.1|WP_043107595.1|1001390_1002719_+|tRNA-5-hydroxyuridine-modification-protein-YegQ	gnl|CDD|237969	PRK15452, PRK15452, putative protease; Provisional.	0
NZ_AP012978.1|WP_052199307.1|1006481_1007234_+|serine/threonine-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	2.96486e-61
NZ_AP012978.1|WP_171816185.1|998657_999896_-|diguanylate-cyclase	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.07541e-46
NZ_AP012978.1|WP_081999821.1|1007713_1008160_-|hemerythrin-domain-containing-protein	gnl|CDD|179353	PRK01917, PRK01917, cation-binding hemerythrin HHE family protein; Provisional.	3.59955e-33
NZ_AP012978.1|WP_043107602.1|1011319_1011895_+|HupE/UreJ-family-protein	gnl|CDD|368209	pfam04955, HupE_UreJ, HupE / UreJ protein. This family of proteins are hydrogenase / urease accessory proteins. The alignment contains many conserved histidines that are likely to be involved in nickel binding. The members usually have five membrane-spanning regions.	1.01072e-41
NZ_AP012978.1|WP_043107598.1|1004706_1005615_+|site-specific-tyrosine-recombinase-XerD	gnl|CDD|234713	PRK00283, xerD, tyrosine recombinase.	5.56141e-164
NZ_AP012978.1|WP_043107588.1|990942_991857_+|hypothetical-protein	gnl|CDD|366517	pfam01213, CAP_N, Adenylate cyclase associated (CAP) N terminal.	0.00351938
NZ_AP012978.1|WP_043107597.1|1003917_1004361_-|YcgN-family-cysteine-cluster-protein	gnl|CDD|235356	PRK05170, PRK05170, YcgN family cysteine cluster protein.	5.16726e-77
NZ_AP012978.1|WP_043107593.1|997683_998676_+|dimethyl-sulfoxide-reductase-anchor-subunit	gnl|CDD|113736	pfam04976, DmsC, DMSO reductase anchor subunit (DmsC). The terminal electron transfer enzyme Me2SO reductase of Escherichia coli is a heterotrimeric enzyme composed of a membrane extrinsic catalytic dimer (DmsAB) and a membrane intrinsic polytopic anchor subunit (DmsC).	3.76055e-19
NZ_AP012978.1|WP_043107596.1|1002913_1003921_-|DUF3549-family-protein	gnl|CDD|378801	pfam12069, DUF3549, Protein of unknown function (DUF3549). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 340 amino acids in length. This protein has a conserved LDE sequence motif.	3.18547e-138
NZ_AP012978.1|WP_043107601.1|1008296_1011119_-|valine--tRNA-ligase	gnl|CDD|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_AP012978.1|WP_043107591.1|993850_996757_+|molybdopterin-dependent-oxidoreductase	gnl|CDD|239164	cd02763, MopB_2, The MopB_2 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_AP012978.1|WP_043107603.1|1011891_1012554_+|HupE/UreJ-family-protein	gnl|CDD|368209	pfam04955, HupE_UreJ, HupE / UreJ protein. This family of proteins are hydrogenase / urease accessory proteins. The alignment contains many conserved histidines that are likely to be involved in nickel binding. The members usually have five membrane-spanning regions.	3.42621e-06
NZ_AP012978.1|WP_043107587.1|988790_990677_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|236861	PRK11147, PRK11147, ABC transporter ATPase component; Reviewed.	0
NZ_AP012978.1|WP_043107592.1|996779_997502_+|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|319873	cd10551, PsrB, polysulfide reductase beta (PsrB) subunit. This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.	7.24493e-84
NZ_AP012978.1|WP_043107599.1|1005722_1006442_+|DsbC-family-protein	gnl|CDD|239318	cd03020, DsbA_DsbC_DsbG, DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds formed by DsbA and prevent aggregation of incorrectly folded proteins. DsbC and DsbG are kept in their reduced state by the cytoplasmic membrane protein DsbD, which utilizes the TRX/TRX reductase system in the cytosol as a source of reducing equivalents. DsbG differ from DsbC in that it has a more limited substrate specificity, and it may preferentially act later in the folding process to catalyze disulfide rearrangements in folded or partially folded proteins. Also included in the alignment is the predicted protein TrbB, whose gene was sequenced from the enterohemorrhagic E. coli type IV pilus gene cluster, which is required for efficient plasmid transfer.	3.13415e-77

Protein sequences

>NZ_AP012978.1|WP_043107595.1|1001390_1002719_+|tRNA-5-hydroxyuridine-modification-protein-YegQ
MRTPELLSPAGTLRNLRYAFAYGADAVYAGMPRYSLRVRNNDFDETNLRIGIEEAHRLGRQFFVAANVMPHGAKLQTFLDDMAPVVAMGPDALIMADPGLILLVRERWPETPIHLSVQANTVNAAGVRFWQQAGVSRVILSRELSLDEIAAIREACPDVELEVFVHGALCIAYSGRCLLSGYFNHRDANQGTCTNACRWDYRIGREAFEASQDTAIPSVPLSEVKRHPAADAVYYLEEGRRPGELMPIFEDEHGTYIMNSRDLRAVEHVQRLVEIGIDCLKIEGRTKSHYYTARTTQVYRRAIDDAVAGRPFDPALLAELEHLANRGYTDGFFQRHETHELQEYREGASRARKSQFVAEIAGFDADTGLAELAVKNKFRTGDEMELVTPAGNHRFRLEALYDQRGDRLEEAPGGGWTVRAPLPVAADETAFLTRLFPAEGAG
>NZ_AP012978.1|WP_171816185.1|998657_999896_-|diguanylate-cyclase
MSRRAPVLRPIATQTAVTAELLQGAPRTLVASHLVALLTYAILLEHVAFEQITLWILGFSVINFARLFLAWHELQHFDEHPLHSARRYALGALAGGSCWGSLMLFHDPNMPVAVQLMMITTLVCLPPASLPSNAVHPPTFLAFALPIFVSLVSWGVFLAPGNNLAFTVVAIIYAGLILASGLRYALVLRDNLVRNAENRRLLRNVKEINSRLLRFAYQDPLTKLSNRRRFDEYADRLLQQAQNNGLELSLVLIDIDNFKEVNDTLGHEAGDRLLRIVAKRITTVSRHTELLTLERFEAARIGGDEFVVLYLGTPGEMHADAIAQRVLEAIQQPLELCGKTFAPRVSIGVAWIGARPMTWRHCCARPMPPCIAPSRPAGIASSITPATRACTSSMAARGPESPQHWPAHPTVW
>NZ_AP012978.1|WP_043107593.1|997683_998676_+|dimethyl-sulfoxide-reductase-anchor-subunit
MHPAFSVIFLTTLIGAAQGMFMALVTGQVYSMANLLEPQDSVTFYAAGSLIALLLLGGGLVAAVFHLGKPSYFITRAWRGVTQWRTSWLSRELIALPAFMFLVFLYGVVHYMGWTDTLFTIKGVIPVDLSLIIGTLGVLMAITLFISTAMIYASLRFLQEWHSPLTVVNFILFGMASGFTLTAAFSAWTGVDLVGFYGTWAVLFTIMAFVTRFWSMLRNQRIKHKSDMRSALGIRHTKITQRSMGFMGGSFNTKEYFHGKSGAFVEAVRLFFLVMVFAVPVALLAASNALESRCLPALAFLAQYIGLLAERWYFFAEAKHPQNLYYQTVG
>NZ_AP012978.1|WP_043107592.1|996779_997502_+|4Fe-4S-dicluster-domain-containing-protein
MTQLALVIDLNVCVGCHACVTSCKEWNTSGWAGPMVDQRPYDADSTGTFFNRVQTFEVGEYPNTETVHFPKSCLHCEEPPCVPVCPTGASYKRKDNGVVLVDYDKCIGCKYCSWACPYGVRELDEMQKVMKKCTLCIDRITDESKPESERKPACVLACPTSARLFGDVHDPDSEASVAIRERGGYQLMPEWGTQPANHYLPRRKTRIQIFEDELERVDNPLDKEHPLPAASGETLDDVTF
>NZ_AP012978.1|WP_043107591.1|993850_996757_+|molybdopterin-dependent-oxidoreductase
MLDPTEYKESETGRIEVKNTTCYMCACRCGIRVTLRDGEVRHIEGNPEHPLNKGVICAKGASGIMKQYSPARLTRPLLRRKGAERGEADFEPISWDRAFEIMEERLSHLRETDPSKFAIFTGRDQMQALTGLFAKQFGTPNYAAHGGFCSVNMAAGMIYTIGGSFWEFGGPDLDRAKLFVMIGTAEDHHSNPLKIAISKFKRRGGRFISINPVRTGYSAIADEWVPIRPGADGALFLAIIHELIAQGLYDREFLINYTNAAELINLDEASDDYGMFIRSDRPVEDGCFDPQNKLWWDRITNRPVDVRSEGADPFLLGEYEIDGKPVKTAFQLLKERVDEYSPEWAEGITGIPADTIRRLAHEMGVTARDQKIELPIQWTDVWGKEHQSVKGGPVAFHAMRGLAAHSNGFQTIRAMSVLMTMLNTIDTPGGFRHKAPFPRPIPPCPKPPKSREDVQPNTPLNGMPLGWPADPNDLFVDEDGEPLRIDKAFSWECPLSVHGLMHNVITNAWRGDPYKIDTLLLFMANMAWNSSMNTANVREMLTDKDENGEYKIPFLIVCDAFHSETVAFADLVLPDTTYLERHDAMSMLDRPISEFDGPVDSVRIPVVPPKGECKPFQDVLVELGSRLKLPAFVNEDGSRKFRDYPDFIVNFETSPGSGIGFLAGWRGKGGEKFLKGEPNPRQWEMYAKNNCVFHYELPKSYQYMRNWNKGYLEWARAHGMTRYAEPINVHIYSEVLQKFRLAAQGRRPGRQPPERLRQRIITFMDPLPFYHETLEASLVDTQEFPLNAVTQRPMAMYHSWDSQNAWLRQIHTHNYLYVSPKLGEAQGFEDGDWVWVESPHGKVRCMVRFSESVEPGTVWTWNAIGKAAGAWGLSPKANESQKGFLLNHVISEELPPCESGEHISNSDPITGQAAWYDVRVKVYKASESEPKRTFPQFKPQRRVPGMDPKRGRWQAYFAGMFRKKTGIN
>NZ_AP012978.1|WP_148307664.1|993197_993653_+|hypothetical-protein
MPVVVRFLPLLFALGWLMPSSRPVQAAGAACVMAKFQGQTLDYELAITRGHVSEAQDQAIERLRKKGYADYYKHLDIIRPQNLTNLEHAYVIVIRSDFKDRRGKKRSVVGCGFSARSWDDALWDALRDAQSYFWGWKPDRDGYRVIRKLRY
>NZ_AP012978.1|WP_052199306.1|992587_993142_+|hypothetical-protein
MDMPPPELDPRRPIVEVMARIGRETQITLDEREHHFRITDTVIVVISILLIVLAVFNLYYVRVLYKDLDRIVGNMESMVTRLDQVDRDMGLVAGHVAAFQAHMQQMTPITGHVVQVTDRLPGMREDMSLMAESMRLINQDMAQLRQAVGTITPNMMQMTGNIARMRQDVRRIADPMGTFNPILP
>NZ_AP012978.1|WP_043107589.1|991990_992572_+|hypothetical-protein
MASELPEPKASADESVLQAQYLRALSSFEGIMLAQIEMKTQLSNRLNWTIRAGLILLGGIATSILVLLLTLSSQINRMSDMVVAMNSHFESVTTRMDNITQVMGSMEKQVALMGQVGEATAKMDEEMAAMQGYMQHMRGDVAGVQRELSAVKDEMAGIAATIHSMNGEVGVMGREMHRLSKPARTFNRMFPFP
>NZ_AP012978.1|WP_043107588.1|990942_991857_+|hypothetical-protein
MRRKLFWLAFTLFLASCGTPPKAPAPKPAPPPPPPRKPPVDTVLEQLERDLPPERDLVREPYRYDRAISMGRVPGIKLYTYTPGRQEKVVGFALVNKGSPWVNPRGLEGTGARREFLFQYPDRAREEIFLSVLDDVRISKRYSHDNMFRELHFFPRRQLPSLVREGDRLRVHLPTGESVVFDAATAEIVDGVLEEQPIDFNRNRHARHNPRIRYRGEGLVITVAQRGEAPRRARVWGRKKLAEIRYPSRYRKRCRLSPALLWDQRPKPGDTDPRLTWKLKSDDALFDLVEKRCGWDLSALREGS
>NZ_AP012978.1|WP_043107587.1|988790_990677_+|ATP-binding-cassette-domain-containing-protein
MALLSLRDIHLSFAHPPLLDGVSLSIEDGERICLIGRNGEGKSTLLRIIAGELAPDEGERVLRRGARVARLEQAVPEDLAGTVFEVVADGLGEIAALVKDYHAAGAALGETADERALARLAQAQQALEQAGGWQVQQRVETILSRMGLDGEVDFASLSGGMKRRVLLARALAGDPDLLLLDEPTNHLDIEAIAWLEEFLLGWRGALVFITHDRGFLRRLATRIVELDRGGLRDFPGDYDTYLRRREALDRAEARERARQERLLAQEEAWIRQGIKARRTRNEGRVRRLQALREEARARRARQGTARIALNSAERSGRLVCELEDVDYAWDGRPVIRGFSTTILRGDRVGIIGPNGCGKSTLLNLMLGRLQPDCGQIRLGTRLEVAYFDQLREQLDLDRTVQDNVAGGSDKVVVNGREQHVISYLADFLFPPARARQPVRALSGGERNRLLLARLFTRPFNLLVMDEPTNDLDLETLELLEERLLDFDGTLLLVSHDRDFLDNVVTSTLVFEGEGRIGEYVGGYSDWQQQRPAPSSTEGEKERAAPAREAKRERAERPRKRSYKEQRELDALPERIEQLEAELAEVQQQLSDPAVYEQQGADGLAGLGERLKALEEALEAAYARWEELE
>NZ_AP012978.1|WP_043107596.1|1002913_1003921_-|DUF3549-family-protein
MTLTEFLENTGATLRFYDLGRRVAPVTREDFLAFEHADRPWPTPMQQKAWLALVLTPGDDREPLIWFLCFDLDEQGLLVQATRDYLLGRFAEIASEGPDPQTLGEALRENPLAFAPREDKMANLHAQVHQALGLPPSQYHAHAHDYLAGRLGWDQWSFVGFQGLADIAARQHKDDDGLLARAIPHLPPEPLIALCQCLEHHVPGPGLDQALHARLRLALDAPFTSPVLFAALLRGLSRGAREPLRTAIREVLARPQSSDPEVLAAIGGRAWEALDDPDTARAWLERLADEAVPTGVFAHCVGDLLRLPGMREPLLGVLRSPDASERLKKAFEALG
>NZ_AP012978.1|WP_043107597.1|1003917_1004361_-|YcgN-family-cysteine-cluster-protein
MTRPDPNFWRHKTLAEMTREEWEALCDGCARCCLYRLEDADTGEIHFTNVHCRLLDTATGRCTDYANRSTRASDCITITLDTLRSPGWLPRSCAYRLLAEGKPLPSWHPLVSGDPDSVVSAGQRVCDRTVCEDEADALENHLVDWLK
>NZ_AP012978.1|WP_043107598.1|1004706_1005615_+|site-specific-tyrosine-recombinase-XerD
MRVAVPSSEQRLIERFADALWMERGLSDNTLAGYRTDLQDLAAWLAGEGSDLLRASRAELQAYLASLVQRGLKVRTSARRLSGLRQFYRWAAREGLTAEDPTALIEMPRQGHPLPHSLTESQVEALLQAPDLDSPEGVRDRCMLELLYATGLRVSELVGLRAEQIGLAQGVVRVVGKGNKERLVPMGDEAADWVRRFAAGARRELLGERACEAFFPTRRGAGMTRQAFWYRIKQHARQAGITTPLSPHTLRHAFATHLLNHGADLRVVQLLLGHSSLSTTQIYTHVARERLQRLYEQHHPRA
>NZ_AP012978.1|WP_043107599.1|1005722_1006442_+|DsbC-family-protein
MNRLFSMLVWSLLTTSLLVGHAQAATDGAEKVRASLAVLIPHLKVDSVTPSPIPGLYEVTFGNHIVYVTEDGKYLVQGRITNLETREPITELRERALKKALLDRLDEKDMIVYGDEDLPYTVTVFTDIDCPYCRKLHSQVDQYNKEGIRIRYLAYPRAGPGSSSEKKAEAVWCAEDRKQAMTLAKSGGKVPYRKCDNPVREQYRLGQDLGITGTPALVLDDGEIIPGYVPPKQLRAALD
>NZ_AP012978.1|WP_052199307.1|1006481_1007234_+|serine/threonine-protein-phosphatase
MAVHPLECAHLTHVGLVRQHNEDYLACFPDQGILVLGDGMGGHRAGEIASRIAMEAAAEALLPAQEEDAADDLESLLRIGRAAEVANRAVFAAVDRDPGLRGMGTTLVAAMFRERHVYFSHVGDSRLYRLRDGYLRCLTRDHSLVQEVLDNGLFANRAEVHAAGIRDNILTRCIGLDPDMEVDVGDAELQQGDIYLACSDGLCGRVSDETLRHVMLSHPDLEGMARELMDVALAAGGQDNISIILARPQL
>NZ_AP012978.1|WP_043107600.1|1007264_1007588_-|ferredoxin-family-protein
MTFVVLENCIKCKYTDCVEVCPVDCFREGPNFLVIDPDECIDCALCEPECPAEAIVSDDDLPPDQEQFLALNAELAAEWPVISQKKDPPPDADEWNGTPNKLPLLER
>NZ_AP012978.1|WP_081999821.1|1007713_1008160_-|hemerythrin-domain-containing-protein
MPEPMENAAMVYEWDSKLEKGIATMDAVHREFVERVDRALRAPDEELASALQELVAHTHEHFERENRWMEECGFPPIMIHRGEHQRVLEAMEETLRRARGGELAPARQLVEQLPAWFEQHAATMDNALAMHMRHTGHPETTEASNALE
>NZ_AP012978.1|WP_043107601.1|1008296_1011119_-|valine--tRNA-ligase
MDNTYNPHVIEQRWYQTWESKGWFAPDMNAPGAPYCIMIPPPNVTGSLHMGHGFNNTVMDTLIRYHRMKGDKTLWQPGTDHAGIATQMVVERQLEAEGLSRHDLGRDKFIERIWEWKEESGGTITRQLRRLGSSLDWAHERFTMDEGLSEAVKEVFVRLYEEGLIYRGKRLVNWDPKLHTAVSDLEVISEEEAGHMWHMRYPLSNGTGYLVVSTTRPETMLGDCAVAVNPEDERYKHLIGELVELPLTGRKIPVVADEHADPEFGTGCVKITPAHDFNDYEVWLRHRDEKAIAEQIHGGLINIFTVDAAIRENLPEESELIPAKYIGLDRYEARKAIVADLEAAGLLEKVVDHKLMVPRGDRSGVVIEPFLTDQWYVKVGPLAKPAIEAVESGRIRFVPDNWKNTYFEWMRNIQDWCISRQIWWGHRIPAWYDAEGNVYVGRSEAEVREKHELAPDYPLTQDEDVLDTWFSSALWPFSTLGWPEDTERLRTFYPTSVLLTGFDIIFFWVARMIMMGLKFMDDVPFREVYVHGLVRDSQGQKMSKSKGNVLDPIDLIDGISLEDLIAKRTRGMMQPQLAKKIEQQTRKEFPEGIPSFGTDALRFTFAALAATGRDIKFDLGRIEGYRNFCNKLWNAARYVLMNTEGQDCGLGGEPVEYSAADRWIRARLQQVITEVTTAIEGYRFDQMANALHDFIWNQYCDWYLELSKAVLNAPDTTEAQRRGTRQTLVQVLETLLRLTHPVMPFITEEIWQRVRSLAGAEGETIMRQSWPQVDAGWQDSDAEAEMDWVMQFILGVRRIKGEMNIAPGKPVPILLANASERDRERLARHRLYLDALARPESIEVLEKDSREPESAIALVGEMKILIPLAGLIDKEAEITRLEKEIGKLEADIARVRKKLENPNFVDKAPAAVVQKERDRLDKSQGALEQLATQLDKIRSL
>NZ_AP012978.1|WP_043107602.1|1011319_1011895_+|HupE/UreJ-family-protein
MKRLSILLLGLLVLPAHAHVAGGLAGGFTAGLLHPVLGLDHVVAMVAVGLWGAFLGQPAIWLLPVVFPLVMTVGGALGILGVPWPAVETGIAVSAIVLGLMVAFAVRPPLWLAALIVGFFAVFHGYAHGAELPSSAGPLAFSLGFVVSTGLLHLSGVALGLLTRWQGGRRLVQAGGGVIALIGVAYLVGLL
>NZ_AP012978.1|WP_043107603.1|1011891_1012554_+|HupE/UreJ-family-protein
MSVRWLWLALVLPGAALAHSPIKGLGDFYNGILHPLFVPAQLLLVVALGLVTGQQGVQRHLPAVAGYALGVVAGLTLIGQYPQVVTPEQLEVAILGTAVALALLVVLARSLPRVLLTVLAALAGLLLGLDSLQSDPAGSARTAALFGSGIALYLLMLYPMALAERFQGHAWTRIGTRVLGSWITASALLVLALALSPLRPAAPGSIPTPGDPRTSTAPPR

Crispr_ID: NZ_AP012978_8

• CRISPR_ID: NZ_AP012978_8
• CRISPR_location: 1356411-1356540
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_AP012978_8

Consensus_repeat	Method
AGGAGCGGCGTCTTCGCCGCGAAC	CRISPRCasFinder

spacers of NZ_AP012978_8

>8.1|1356435|29|NZ_AP012978|CRISPRCasFinder
GGTTCCGTCCAAGGACGCCCCCCTGCGGC
>8.2|1356488|29|NZ_AP012978|CRISPRCasFinder
ATTCGGCCCGGGACGGGCCTCCTATCCGT

CRISPR arrays and Neighbor proteins around NZ_AP012978_8

CRISPR arrays

The CRISPR arrays of NZ_AP012978_8

>merge|NZ_AP012978|8|1356411-1356540|CRISPRCasFinder
AGGAGCAGCGTCCCCGCAGCAAACGGTTCCGTCCAAGGACGCCCCCCTGCGGCAGGAGCGGCGTCTTCGCCGCGAACATTCGGCCCGGGACGGGCCTCCTATCCGTAGGAGCGGCGTCCTCGCCGCGAAC

>NZ_AP012978|8|7|1356411-1356540|CRISPRCasFinder
AGGAGCAGCGTCCCCGCAGCAAAC	GGTTCCGTCCAAGGACGCCCCCCTGCGGC
AGGAGCGGCGTCTTCGCCGCGAAC	ATTCGGCCCGGGACGGGCCTCCTATCCGT
AGGAGCGGCGTCCTCGCCGCGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_052199363.1|1345254_1346868_-|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|223910
NZ_AP012978.1|WP_052199364.1|1355468_1356341_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NZ_AP012978.1|WP_171816146.1|1346940_1348071_-|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NZ_AP012978.1|WP_043107864.1|1357235_1358111_-|rRNA-pseudouridine-synthase	unknown	unknown	gnl|CDD|224108
NZ_AP012978.1|WP_171816202.1|1349839_1351090_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_AP012978.1|WP_043107859.1|1353732_1354143_+|DoxX-family-protein	unknown	unknown	gnl|CDD|225168
NZ_AP012978.1|WP_043107856.1|1344298_1345168_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_AP012978.1|WP_052199365.1|1356571_1357249_-|endonuclease	unknown	unknown	gnl|CDD|225140
NZ_AP012978.1|WP_043107873.1|1363249_1364059_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043107861.1|1354144_1355182_-|thioredoxin-fold-domain-containing-protein	unknown	unknown	gnl|CDD|239249
NZ_AP012978.1|WP_043107875.1|1364377_1364782_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043107867.1|1359681_1360896_-|tryptophan--tRNA-ligase	unknown	unknown	gnl|CDD|183401
NZ_AP012978.1|WP_171816147.1|1348045_1348468_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043107874.1|1364075_1364381_+|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl|CDD|225328
NZ_AP012978.1|WP_070104721.1|1358103_1358844_-|SMC-Scp-complex-subunit-ScpB	unknown	unknown	gnl|CDD|377219
NZ_AP012978.1|WP_043107869.1|1360916_1361588_-|site-2-protease-family-protein	unknown	unknown	gnl|CDD|100079
NZ_AP012978.1|WP_043107872.1|1361595_1362222_-|threonylcarbamoyl-AMP-synthase	unknown	unknown	gnl|CDD|183245
NZ_AP012978.1|WP_043107857.1|1351130_1352270_-|MFS-transporter	unknown	unknown	gnl|CDD|372338
NZ_AP012978.1|WP_052199613.1|1358845_1359616_-|segregation/condensation-protein-A	unknown	unknown	gnl|CDD|224273
NZ_AP012978.1|WP_043109372.1|1352292_1353396_-|chorismate-synthase	unknown	unknown	gnl|CDD|235438

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_052199363.1|1345254_1346868_-|methyl-accepting-chemotaxis-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.02073e-64
NZ_AP012978.1|WP_052199364.1|1355468_1356341_+|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	5.21247e-63
NZ_AP012978.1|WP_171816146.1|1346940_1348071_-|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	3.29486e-72
NZ_AP012978.1|WP_043107874.1|1364075_1364381_+|heavy-metal-associated-domain-containing-protein	gnl|CDD|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	2.89389e-11
NZ_AP012978.1|WP_043107864.1|1357235_1358111_-|rRNA-pseudouridine-synthase	gnl|CDD|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	6.08367e-96
NZ_AP012978.1|WP_043107859.1|1353732_1354143_+|DoxX-family-protein	gnl|CDD|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	4.26994e-09
NZ_AP012978.1|WP_043107856.1|1344298_1345168_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.59031e-48
NZ_AP012978.1|WP_052199365.1|1356571_1357249_-|endonuclease	gnl|CDD|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	1.4371e-80
NZ_AP012978.1|WP_043107861.1|1354144_1355182_-|thioredoxin-fold-domain-containing-protein	gnl|CDD|239249	cd02951, SoxW, SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide fixation during autotrophic growth and the respiratory electron transport chain. It is unclear what the role of SoxW is, since it has been found to be dispensable in the oxidation of thiosulfate to sulfate. SoxW is specifically kept in the reduced state by SoxV, which is essential in thiosulfate oxidation.	5.26049e-29
NZ_AP012978.1|WP_043107867.1|1359681_1360896_-|tryptophan--tRNA-ligase	gnl|CDD|183401	PRK12283, PRK12283, tryptophanyl-tRNA synthetase; Reviewed.	0
NZ_AP012978.1|WP_171816202.1|1349839_1351090_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	5.0954e-28
NZ_AP012978.1|WP_070104721.1|1358103_1358844_-|SMC-Scp-complex-subunit-ScpB	gnl|CDD|377219	pfam04079, SMC_ScpB, Segregation and condensation complex subunit ScpB. This is a family of prokaryotic proteins that form one of the subunits, ScpB, of the segregation and condensation complex, condensin, that plays a key role in the maintenance of the chromosome. In prokaryotes the complex consists of three proteins, SMC, ScpA (kleisin) and ScpB. ScpB dimerizes and binds to ScpA. As originally predicted, ScpB is structurally a winged-helix at both its N- and C-terminal halves. IN Bacillus subtilis,one Smc dimer is bridged by a single ScpAB to generate asymmetric tripartite rings analogous to eukaryotic SMC complex ring-shaped assemblies.	5.68051e-66
NZ_AP012978.1|WP_043107869.1|1360916_1361588_-|site-2-protease-family-protein	gnl|CDD|100079	cd06158, S2P-M50_like_1, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with a minimal core protein and no PDZ domains.	9.78596e-63
NZ_AP012978.1|WP_043107872.1|1361595_1362222_-|threonylcarbamoyl-AMP-synthase	gnl|CDD|183245	PRK11630, PRK11630, threonylcarbamoyl-AMP synthase.	1.07613e-96
NZ_AP012978.1|WP_043107857.1|1351130_1352270_-|MFS-transporter	gnl|CDD|372338	pfam12832, MFS_1_like, MFS_1 like family. This family contains proteins related to the MFS superfamily.	2.67226e-122
NZ_AP012978.1|WP_052199613.1|1358845_1359616_-|segregation/condensation-protein-A	gnl|CDD|224273	COG1354, scpA, Rec8/ScpA/Scc1-like protein (kleisin family) [Replication, recombination, and repair].	7.56651e-65
NZ_AP012978.1|WP_043109372.1|1352292_1353396_-|chorismate-synthase	gnl|CDD|235438	PRK05382, PRK05382, chorismate synthase; Validated.	0

Protein sequences

>NZ_AP012978.1|WP_052199364.1|1355468_1356341_+|GGDEF-domain-containing-protein
MVETQQMHGPVTPPAPETLGPRVLELSGILQTTLDLEQQITLFARSIRDDVPIDGLEYDNPAARVLIRHGEQTTHKAAYDLQLDDRSLGVISFFRDLPFSEDELHTLENLLCALVYPLRNALSYLEALRLASHDPLTGIQNRLALEHALQREVDLARRQRATLSMLVIDADHFKRFNDEYGHAFGDDVLRALANAMSATVRRSDLLFRYGGEEFVVLASHAGRDGARLLAERIREAVAGIRTIDGQPVDLSVSIGVAELTEDESPESLFERADQAVYQAKEAGRDRVELA
>NZ_AP012978.1|WP_043107861.1|1354144_1355182_-|thioredoxin-fold-domain-containing-protein
MRSLLLICCCLLSLGLHATPASEAALLEAGVNPGYEEKPAWFKESFLDIREDVAEAAEAGKRVILYFYQDGCPYCAKLLKDNFGNRAIAEKAQRHFDVIAINMWGDREVTDFAGRPATEKQFASALRVQYTPTLLMLDEQGQVVLRINGYFEPHKFDVALDYVAGHHEKEGDFRSYYARVSPVPASGKLHELPGSLPHPLRLKDAPERTWRPLVVFFEQRVCRECDELHQDILERRAVATALTNLDTAVVDIWSKEIVQTPDGRELPARDWARELGIQFAPSLVFFGADGKEVFRTEAYLRTYHLHGAIDYVVSGAWRHQPNFQRFLQHRTDLLHARGFKVDLME
>NZ_AP012978.1|WP_043107859.1|1353732_1354143_+|DoxX-family-protein
MFEQSSSLSGDIGRLVLRLSLGALILFHGIAKILHPQAIDFITGRLAASHLPTFLVHGVYVGEILAPLMLLFGIFTRLAGVLVAINMLFAIFLVHRHQLFALTENGGWQLELQGLYLLCGIAVALLGGGRFALVRD
>NZ_AP012978.1|WP_043109372.1|1352292_1353396_-|chorismate-synthase
MSGNTIGKIFTVTSFGESHGPAIGCIIDGCPPGMALSAADIQPDLDRRRPGKTRHTTQRREPDEVQILSGVFEGKTTGTPIGLLIHNTDQRSKDYGEIAQKFRPGHADYTYIQKYGIRDYRGGGRSSARETAMRVAAGAVAKKYLRERCGVVIRGYLSALGPNRPTSFSWEPVENNPFFWPDAGQVAELEAYMDALRKSGDSVGAEVSVVAEGVPPGWGEPVFDRLDADIAHALMSINAAKGVEIGAGFASVAQKGTEHRDQMTPEGFLSNHAGGVLGGISSGQDIATRLAFKPTSSIRLGGQTVDVQGAPVDVITKGRHDPCVGIRAVPIVEAMLAIVLMDHALRHRAQNADVRPETPVIPARPGD
>NZ_AP012978.1|WP_043107857.1|1351130_1352270_-|MFS-transporter
MPYWRLSSFYFFYFAVLGILVPYWGLFLQHRGFDAMAIGQLMAILMATKIVAPNLWGWLGDYLGHRMMIVRAASLASVLVFGLMFVVRDFWAVALAMALYSFFWNASLPQFEVITLNYLGDRATRYARIRAWGSIGFIIAVVALGVLVDRAGTAVVLPSVMVIFVSIWLTSLTVRDPDPEPHPAQQVSLGSLLRQPPVIAFFVAVMLMQASHGPYYTFYSIYMEDHGYSKTLIGQLWALGVLAEVAIFMVMHRLLERFEAARVLVASLGLATLRWLLIGYLPGSVVALLFAQLLHAATFGTFHGAAIDLVHRQFPGRLQGRGQALYSSLSFGVGGAIGSLASGLAWDALGPATSFLLAALTALLGALVVWKGLCGAARA
>NZ_AP012978.1|WP_171816202.1|1349839_1351090_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MAVTQDKRRGACWPWLVLGLMGLVAAGLIATRPQTEPLAIKERAWRVAVVAAEPQTLAPHLTLYGRLESLWSTQLSAPVAAEVLEVAVTEGETVRRDQVLVRLDERDSRLRLQQREAEVRDARARIEAARDQVRLELERCTVRAPFDGCVARLSTAPGRRTRIGDPLLTVYDTGAMVVRALIPERYLPRVRAAMAAGAPPEVRGELDGIGLNGRLRGLSGEVTAGSGGVSGLFDIQGDIGVLRQGRLLRLDMTLPAEPDVVVLPHEAVYGVDKVYIVDRESRMRPVRVERLGEVRGDDGAARACWCARRHCGPACVSWSLICPTRSTGCWCVSRKGRARELPASRGHHRHLRPSPGGGQPADGDDAARRGLGPGQSERPVLSQLRGRGRHRAHPVERGQRRGRGTLVDPAAGAGPA
>NZ_AP012978.1|WP_171816147.1|1348045_1348468_+|hypothetical-protein
MSRPGCPPMRTVVVRYSSPGGQIQASAPFGDELLVAHRAAVGRRELHHDGGKLVAALGLPRIGEIPQSVTHPRHSDQPATKVRIGGIQGLLDLIDETAHPRRRRARHEGGRGHHHVARHIGKEAEAQATADHQPDQEHDA
>NZ_AP012978.1|WP_171816146.1|1346940_1348071_-|efflux-RND-transporter-permease-subunit
MGGHPGRDIEIRLGGADPEHLKQAALDLAQALAAVPGVGSVEDDMPYGQQQLVFRLRPYGEALGLTVDEVARQLRAAFDGQLAQIFNEGDEEVEVRVMLPDSERHRLAALDDFRVFLPGGGNVPLDTVVELSERRGYKALRHEDGRLAVKVYADVDKRVASNNAVRARLAETVLPELERRHDIHWEFTGRAKDQAETMADMKRGALFALAMIYIVLAWVFGSYGWPLVVMAIIPFGVVGALLGHFVMGITPTILSMFGLFALSGIAVNDSIILVVFYKQLRQQGMAVRDALVEAACQRLRAVLLTSLTTIAGLLPLLFETSLQAQFLIPMVVSISFGLMFTTFLVLLLVPSLLSAMEGLLLRRGEGDQAAGATIGT
>NZ_AP012978.1|WP_052199363.1|1345254_1346868_-|methyl-accepting-chemotaxis-protein
MNRFRGIQGRFLVLTVVLGALLLVGNGIVFYNNQALVQEADRIAERSLPLVNTAHEMKLAVVEVQQWLTDISATRGQDGLDDGFDQARANAERFRQSLQKIQQFAPELDVKQGDILQAFEAYYAVGQQMAKAYIEGGPAAGNRMMGAFDATAEKLGGQVDALLEKIQARATARAVHQKTLSHYNGGVLLVVSVVVLGFIGVLYWLISRRLQRLAATLPVVEGIGDGDLSVSLAADRDDEIGRLAQSLEEMRQRLAEIVCDIRGSSRMLVEGTGRLDSVVATAGRNAAEQRLATDQLADTVEQMAASASEIAGRIAEVADAGQKAQDETRGGRESLAGAIGRLGELVRQIEGTSEVIRLLERQSEGITGILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQSSTEEIQQMIEKLVAGVNQAVDSMLASAELAGATMQEATGAEASFDSIVGLVEHVSEMSSHIASAADEQSVVARHIAENVVGIRERADATAASMDEAAGVVSQMGERVTHLDELVGRFRTP
>NZ_AP012978.1|WP_043107856.1|1344298_1345168_+|LysR-family-transcriptional-regulator
MELTLLQAFRAVAEHGSFSQAAEHIHLTQPAVSKRVRQLEEDLGVRLFDRIGRRVRLTEAGRALLPRARRLLNDAAEIRRLLANLSGEVRGRLVMGTSHHIGLHRLPGPLKRFTRAHPEVELDIRFMDSEAACHAVEIGDLELAIVTLPPEPLPRLHSRLIWDDPLVFMVSREHPLAGRRQVALAELLQHPAVLPGSNTYTRGILERAVQAAGLRLRTGMETNYLETLRMLTEANLGWSLLPATQLTPQLVALKVAGMHLSRRLGAVTHEGRSLSNAARAMIAACVETR
>NZ_AP012978.1|WP_052199365.1|1356571_1357249_-|endonuclease
MPKTEDFAPSSGALIALYERLRAAHGAQDWWPADSPFEVVVGAVLTQNTAWTNVERAIAGLKGAGMLSCEAILAASHEELAERIRPAGYFNVKARRLRSLCAFLAGEGGLEALAGLPTTTLRPALLAVNGIGPETADDILLYALDRPVFVIDAYTRRLLVRHGLAKGTEDYETLRAGFERALPADVALFKEYHALIVEHAKQACRRRPRCDDCALVEACGRVGVT
>NZ_AP012978.1|WP_043107864.1|1357235_1358111_-|rRNA-pseudouridine-synthase
MPDPRGERLQKVLANAGLGSRREIEQWIRDGRVRINGRVARLGARATEEDRIEIDGRPVAGKRLAGRERFVILYNKPEGEVVTRHDPEGRPTVFDRLPRPPQGRWISVGRLDVNSAGLLLLTNDGELANRLMHPKYQIDREYAVRVHGEVTEDMVRRLVNGIELEDGPARFEDVVESGGEGMNRWFHVVIMEGRKREVRRLWDAVGVQVSRLKRVRYGPVILDSAVKAGQWRELDRVERKALLAAVGMKADRPWGTLFRPGSWLEARARGRKKVVGTPWRRRRATGDDAED
>NZ_AP012978.1|WP_070104721.1|1358103_1358844_-|SMC-Scp-complex-subunit-ScpB
MADPEKLKNIIEAALLASGGTLSLDGMQALFDEAEQPEKKQLREVLARLAEDYQGRGIEVVEVASGWRIQVRQDYSSWVSRLWAERPARYSRALMETLALIAYRQPITRGEIEDIRGVSVSSNIIRTLLEREWIRVVGQRDVPGKPSLYGTTREFLDYFNLKSLDDLPTLAEIRDLDEINRELELDDPDRPADKGTGDADTAGDAKDSGGSGEDVSLEEAAREVLAGTGMDEASPEETVQGTGPDA
>NZ_AP012978.1|WP_052199613.1|1358845_1359616_-|segregation/condensation-protein-A
MPFAVVAGEPQYTLPKDLYIPPDALEVFLDAFEGPLDLLLYLIRRQNLDILDIPIAEITVQYIQYIEMMHELRFELAAEYLVMAAMLAEIKSRMLLPRVHTEDEEEGEDPRAELIRRLQEYERYKQAAEDIHGLPQVGRDVFTVKVEVPHKQLEQKPPEVDLREVLLALKDVLHRADMFSSHQIQREPLSLRERMSRVLDQVNSEGFTAFTDLFDLAEGRPGVVVTFMAVLELIKQQLIELVQAESFAPIHVKARA
>NZ_AP012978.1|WP_043107867.1|1359681_1360896_-|tryptophan--tRNA-ligase
MNAVAAQHARVLSGMRPTGRLHLGHYHGVLKNWVELQHEYQCFFFVADWHALTTHYDDPSAIPQSTWDMVIDWLAAGVNPKEATLFVQSRVPEHAELHLLLSMITPLSWLERVPSYKDQQEKLKEKDLSTYGFLGYPLLQSADILVYRAGLVPVGEDQVAHVELTREVARRFNHIYGRETDFEQKAEQAIKKIGKKAAKLFNNYRRAWQEQGDDEALAAAHALLEAQQNIGVADRDRLFGYLEGGGKVILPEPQPLLTRASKMPGLDGHKMSKSYGNTISLSAPPAKVEQQLRTMPTDPARVRRSDPGEPEKCPVWQFHLVYSDERTQEWVQEGCRSAGIGCLECKQPVIDAVLAELKPIQERAREYEEQPEVVQNIINEGCETAREVARETMDEVRHAMSLDY
>NZ_AP012978.1|WP_043107869.1|1360916_1361588_-|site-2-protease-family-protein
MQELSLIQQLSVMLLPLIFAVTVHEAAHGWVADKLGDPTARELGRITFNPIPHIDLIGTILLPLGLYTLSTLVGGVGFLFGYAKPVPVDAARLNHPRRDMALVAAAGPGANLVMALLWVGVVALAPYIGSQFPGPGVFLMQAGAFGVLINLFLMVLNLLPIPPLDGSRVVTSLLPLSLAHRYARLEPWGLVILLVLLLSGWLGSALVPMVFSLYKLLLGVALL
>NZ_AP012978.1|WP_043107872.1|1361595_1362222_-|threonylcarbamoyl-AMP-synthase
MSQFFQIHPDNPQARLVRQAVEIVRGGGVIVYPSDSSYALGAHLGDKRAMDRIREIRRLDERHNFTLVGRSLSELSAYTKMGNQAHRWIKHLTPGPYTFILPATKQVPKRLMHAKRKTIGIRIPDNRIALALCEELGEPLLSSTLILPGEELPMMDPYEMRDLIGHAVDLIIDGGYCGYEPTSVIAFEDDQPQVVRVGRGDVSLFEPV
>NZ_AP012978.1|WP_043107873.1|1363249_1364059_+|hypothetical-protein
MHRRQLIALLASAALLLPVSASAHDPIFGLGPHVLYKGGIETALEWEAAKAGRERQQALTLELTHGLTGDWAVGLDLPYRFVDDGSAQRQGLGDLALFTKYRFWRADSLALQRSAAVALKIVTDSARDGLDKGATDVITGLSYGHEGRRWYGWASARYRYNGEDGNGLKRGDRWLLDLVGGIRPEPRGYLETDTVWLLELNTEIGRHAQRRGISLPDTGGTEVFLSPGIFWTWRNFAIKAGVQVPVYEDLHGHQDQSDYRFRLTFENHF
>NZ_AP012978.1|WP_043107874.1|1364075_1364381_+|heavy-metal-associated-domain-containing-protein
MQRLSLLLILLFLASAPWAGGTRYEMRVDGLACPFCAYGVEKKLKAIEGTRNIEVDLDHGIVKVDMAEGRELTEEQMRQLFHDAGFTYRSMKKLPIAENGE
>NZ_AP012978.1|WP_043107875.1|1364377_1364782_+|hypothetical-protein
MKEPAIDTRTRGVIWLTLFSTTGTLLCCALPILLVTLGLGGAVVALTGDFPFLIPLTQHKAWIFTLSGLMLLVSGCLLYRPGQECPTDPVLGTACSRAMRWNRRIHGVSVAIWGVGFVAAYLALPLRIWLEGRP

Crispr_ID: NZ_AP012978_9

• CRISPR_ID: NZ_AP012978_9
• CRISPR_location: 1571610-1571689
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP012978_9

Consensus_repeat	Method
TTCGGCCCGGGGACGGGCCTCCTACC	CRISPRCasFinder

spacers of NZ_AP012978_9

>9.1|1571636|28|NZ_AP012978|CRISPRCasFinder
CGTGGGAGCGGCGTCCCCGCCGCGAACA

CRISPR arrays and Neighbor proteins around NZ_AP012978_9

CRISPR arrays

The CRISPR arrays of NZ_AP012978_9

>merge|NZ_AP012978|9|1571610-1571689|CRISPRCasFinder
TTCGGCCCGGGGACGGGCCTCCTACCCGTGGGAGCGGCGTCCCCGCCGCGAACATTCGGCCCGGGGACGGGCCTCCTACC

>NZ_AP012978|9|8|1571610-1571689|CRISPRCasFinder
TTCGGCCCGGGGACGGGCCTCCTACC	CGTGGGAGCGGCGTCCCCGCCGCGAACA
TTCGGCCCGGGGACGGGCCTCCTACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_082000003.1|1572757_1573000_-|transposase	unknown	unknown	gnl|CDD|366690
NZ_AP012978.1|WP_043108066.1|1571922_1572558_+|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|273138
NZ_AP012978.1|WP_148307701.1|1574376_1574910_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_148307699.1|1561826_1563311_-|lysine--tRNA-ligase	unknown	unknown	gnl|CDD|234778
NZ_AP012978.1|WP_148307702.1|1575628_1576138_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_082000004.1|1574908_1575265_+|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|273138
NZ_AP012978.1|WP_043108063.1|1565621_1568279_+|PD-(D/E)XK-nuclease-family-protein	unknown	unknown	gnl|CDD|274682
NZ_AP012978.1|WP_148307703.1|1577379_1577661_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_171816211.1|1558898_1559408_-|paraquat-inducible-protein-A	unknown	unknown	gnl|CDD|377345
NZ_AP012978.1|WP_043108062.1|1565007_1565607_+|DUF2238-domain-containing-protein	unknown	unknown	gnl|CDD|226173
NZ_AP012978.1|WP_043108069.1|1577948_1578188_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_148307700.1|1563495_1564600_-|peptide-chain-release-factor-2	unknown	unknown	gnl|CDD|234799
NZ_AP012978.1|WP_081999880.1|1578675_1579164_-|regulatory-protein-RecX	unknown	unknown	gnl|CDD|234646
NZ_AP012978.1|WP_043108058.1|1560765_1561725_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl|CDD|235580
NZ_AP012978.1|WP_081999879.1|1576241_1577267_-|YaaC-family-protein	unknown	unknown	gnl|CDD|372947
NZ_AP012978.1|WP_043108064.1|1568275_1571602_+|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl|CDD|224000
NZ_AP012978.1|WP_082000002.1|1559394_1560732_-|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl|CDD|182626
NZ_AP012978.1|WP_171816212.1|1574062_1574380_-|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl|CDD|178815
NZ_AP012978.1|WP_043108056.1|1556281_1557748_+|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|273648
NZ_AP012978.1|WP_082000001.1|1555350_1555857_-|DUF2173-family-protein	unknown	unknown	gnl|CDD|370757

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_082000003.1|1572757_1573000_-|transposase	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.00200422
NZ_AP012978.1|WP_043108066.1|1571922_1572558_+|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|273138	TIGR00558, Pyridoxine/pyridoxamine_5'-phosphate_oxidase, pyridoxamine-phosphate oxidase. This model is similar to Pyridox_oxidase from Pfam but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	1.99763e-119
NZ_AP012978.1|WP_148307699.1|1561826_1563311_-|lysine--tRNA-ligase	gnl|CDD|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NZ_AP012978.1|WP_082000004.1|1574908_1575265_+|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|273138	TIGR00558, Pyridoxine/pyridoxamine_5'-phosphate_oxidase, pyridoxamine-phosphate oxidase. This model is similar to Pyridox_oxidase from Pfam but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	6.03029e-68
NZ_AP012978.1|WP_043108063.1|1565621_1568279_+|PD-(D/E)XK-nuclease-family-protein	gnl|CDD|274682	TIGR03623, TIGR03623, probable DNA repair protein. Members of this protein family are bacterial proteins of about 900 amino acids in length. Members show extended homology to proteins in TIGR02786, the AddB protein of double-strand break repair via homologous recombination. Members of this family, therefore, may be DNA repair proteins.	0
NZ_AP012978.1|WP_171816211.1|1558898_1559408_-|paraquat-inducible-protein-A	gnl|CDD|377345	pfam04403, PqiA, Paraquat-inducible protein A. Paraquat is a superoxide radical-generating agent. The promoter for the pqiA gene is also inducible by other known superoxide generators. This is predicted to be a family of integral membrane proteins, possibly located in the inner membrane. This family is related to NADH dehydrogenase subunit 2 (pfam00361).	1.09873e-22
NZ_AP012978.1|WP_043108062.1|1565007_1565607_+|DUF2238-domain-containing-protein	gnl|CDD|226173	COG3647, COG3647, Predicted membrane protein [Function unknown].	1.4145e-74
NZ_AP012978.1|WP_081999880.1|1578675_1579164_-|regulatory-protein-RecX	gnl|CDD|234646	PRK00117, recX, recombination regulator RecX; Reviewed.	1.38672e-40
NZ_AP012978.1|WP_148307700.1|1563495_1564600_-|peptide-chain-release-factor-2	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_AP012978.1|WP_043108058.1|1560765_1561725_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl|CDD|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NZ_AP012978.1|WP_081999879.1|1576241_1577267_-|YaaC-family-protein	gnl|CDD|372947	pfam14175, YaaC, YaaC-like Protein. The YaaC-like protein family includes the B. subtilis YaaC protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 320 and 333 amino acids in length.	5.93789e-82
NZ_AP012978.1|WP_043108064.1|1568275_1571602_+|UvrD-helicase-domain-containing-protein	gnl|CDD|224000	COG1074, RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair].	5.80082e-92
NZ_AP012978.1|WP_082000002.1|1559394_1560732_-|tRNA-lysidine(34)-synthetase-TilS	gnl|CDD|182626	PRK10660, tilS, tRNA(Ile)-lysidine synthetase; Provisional.	2.09538e-109
NZ_AP012978.1|WP_171816212.1|1574062_1574380_-|membrane-protein-insertion-efficiency-factor-YidD	gnl|CDD|178815	PRK00041, PRK00041, hypothetical protein; Validated.	0.00031603
NZ_AP012978.1|WP_043108056.1|1556281_1557748_+|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	gnl|CDD|273648	TIGR01479, Mannose-1-phosphate_guanylyltransferase, mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase (EC 5.3.1.8) (PMI) and mannose-1-phosphate guanylyltransferase (EC 2.7.7.22) in Pseudomonas aeruginosa, Xanthomonas campestris, and Gluconacetobacter xylinus. The literature on the enzyme from E. coli attributes mannose-6-phosphate isomerase activity to an adjacent gene, but the present sequence has not been shown to lack the activity. The PMI domain is C-terminal. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_AP012978.1|WP_082000001.1|1555350_1555857_-|DUF2173-family-protein	gnl|CDD|370757	pfam09941, DUF2173, Uncharacterized conserved protein (DUF2173). This domain, found in various hypothetical prokaryotic proteins, has no known function.	1.7615e-47

Protein sequences

>NZ_AP012978.1|WP_043108064.1|1568275_1571602_+|UvrD-helicase-domain-containing-protein
MTLIGDTIGDTIDDARARELALDPTRSFIVQAPAGSGKTELLTQRFLRLLAGVEEPEQILAITFTRKAAGEMRERILAALHKARGDRPEAEWAQRTWELARAALARDAERGWQLTDNPNRLRVLTFDSLAASLAGQMPVLSRLGSAPHAREDARPLYREAARQLLTRLGDDDIGPALQTVLRHLHNRLGRLEELLVDMLGKRDQWLPHLDADPEDMAQVLRDQIEYHIAVSTQRIPADRLDALVHLARIAAPRVPEGKLAWLRRWAERDTPPSTAWEDLPDWLGLVELALTKSGPSFRTKLTKSEGFPPKDPAKDEMIVLLQALAAEPGLAEALHSLRTLPLAPPDAEQRQLLDALAQVLRLAAAELLLVFQASGELDFVEIQQRALRALGTPDAPGEAALRLDYRLHHLLVDEFQDTSSGQYQLLTRLTAGWEPDDGRTLFLVGDPMQSIYRFRKAEVSLFLQTFKGQLGEIALTPLTLRRNFRSQAGLIDWFNSVFRQIFPVTEDIALGAMPHTPSEAVHPALPGEAVTAHPLNTSDASVEAERVVEIVRQRLAESPGTVAILARARSHLGEIARALGEAGIPYQAVKVAPLADQPTVRDLHALLRALLHPADRLHWLALLRSPLVGLSLDDIVRLAEGEPRHLRTLLADPLARARLSADGRQRAERLHALLEQELPARHRRPLREWLEGFWLALGGAVVGRREDAEAYLALVERHAGPDGIEDLSLLENALAELYAPPDTRPEAERVLLTTLHQSKGLQFDTVILPGLGRKARNDEARLLYWHELPHPEGGTELLIAPIPRRAGADPLVDYLKMIERQKADHEQQRLLYVAATRAESQLHLLGHVKFSKNKKKAGAPYPESSSLLATLWPVVEQYFAELTPPEETADEDAPAAPVSEQRIAADWRLSAPPGIVAPSPTPAGEEPGIEFLWAGDTARHVGTLVHRWLERIAREGLADWPATRIDELPPRFRTALATLGVAPDALGEATDKVTRALRRTLEDERGRWILDGHEQAACELPMTVLDEQGEPRQYVIDRTFIADGVRWIIDYKTGDHQGSDLDSFLDSEQERYRAQLENYGRILRLREDRPVRLALYFPLLGAWREWTP
>NZ_AP012978.1|WP_043108063.1|1565621_1568279_+|PD-(D/E)XK-nuclease-family-protein
MDDLPELDAGTLLLTVNNRLARALRQAHDARQRAAGLTVRDSPHIFSWNAWLRGLYDELVDRGLCDRALLDPHQESLLWEDIIRHAQREDPLLDVAAAARSARQAWQLLHDWRLPLSVLADRHDEEAAQLHAWGRRLREILQRNRWLSAAELPGEAEQALAHEAAPPLPRRLLLAGFDQFTPMQLALHERLRERGCQVETWRPRPLDAMIRRLPCRDAEAECQAAACWARTRLEQDPNARLAIISPALSVHRDRLARWLGRLLDPAGQLPGHTPHPRFDISLGRPLADWPVVAHLLLALRLCRRGELPLHEIGQLLCSPFLGGMPEEADARAALDRVLRESGRPRLDRHRLLGEARRRAPGDPAACPRLIERLEAVQAVLGELPPQDSPNAWAGHLLRLIEAWGWPGPPQLLDSAEYQQAQRLRQAVSEFSHLARVRTHMNLEQALERFARLCRDTDYQPQGRTGGVQVLGVLEAADLRFDGLWLLGLDDATWPPAPAPNPLLPADLQRAHDMPHSSAARELRFARELTGRLLGGAPEIWISHAETEDDKRLTPSPLIAAIDAQEPDFALTDPLYEAARHGHSVPLPPPGHLPPAAPPRGGTALLDDQSACPFRALARHRLGAEALPEPSFAPPPWLSGQMLHRLLERIWGKLGDSQALAEQPAEVLRNRLRALAEETVTELGRDRPDLFEGPLKTLEVERLTERALEWLDHERRRPAPFRVVSREVRETLELAGLPLRVRADRIDALDDGRRIVIDYKTGRGTRLPDWEAERLPEPQVPLYAVHHPPLAGAVLAHIHPDGEQTRFLGLCAEADLLPGASGRAKNVHVPDDWEQTLQDWRERLEGLAREVLEGRAEIAPRDADACRHCDLGGFCRIGHPGGEASE
>NZ_AP012978.1|WP_043108062.1|1565007_1565607_+|DUF2238-domain-containing-protein
MFTDRLPQLLALALTALIVWSGIAPAARDVWIAEIVPILLVFGGLIWLYPRFRFSNTAYLLMAVWLFSHTVGAHYTFAHVPFDWFNELIGSQRNQFDRIGHFSVGFYAFAMTEWLLRTRQCRPLLAGLFGLLLIMAIAAAYEIVEWLFAVYYGGDAGIEFLGSQGDPWDAQKDMLADTLGALTALALYAWLRPDRRLTD
>NZ_AP012978.1|WP_148307700.1|1563495_1564600_-|peptide-chain-release-factor-2
MQDIDINAISNRIADLRGRVDALRGYLDYETKKERLEEVLGELEAPDVWNDPERAQALGKERALLENVVGGIDELTAGLNDAADLLEMAVEENDEDTINAVAEDVDGYEKRVAELEFQRMFSGDMDAANAFLDIQAGSGGTEAQDWAEMLLRMYLRWGEAHGFKTELMEVSPGEVAGIKSATVRFEGPYAYGWLRTETGVHRLVRKSPFDSGNRRHTSFAAVFVSPEIDDSIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHNPTGIVVQCQNDRSQHKNKDQAMKQLKAKLYELEMQKRREQAQAIEETKSDIGWGSQIRSYVLDQSRIKDLRTGVETGNTQAVLDGGLDPFIEASLKSGL
>NZ_AP012978.1|WP_148307699.1|1561826_1563311_-|lysine--tRNA-ligase
MSDQNSQDENRLIAQRREKLKALRERGQAFPNHFRRDALAAELQARYGDKSKEELEQLGQRARVAGRIMTKRGPFMVVQDMSGRIQFYVDKKKLPAELLEQIKLWDIGDIVGGEGVIHKSGKGDLYIYLDEAVLLTKALRPLPEKWHGLADQEQRYRQRYVDLIVNEESQRTFVLRSRIIHYIREYFNAAGFLEVETPMMQVIPGGATARPFVTHHNALDMALYLRIAPELYLKRLVVGGFEKVYEINRNFRNEGLSTRHNPEFTMIEFYEAYVDYHHLMDRTEELLRGIARDVIGSEQIEYQGQTYDFGKPFARMTVKESILHFNPDISEADLDDLERARAVAERLGIPLKDSYGLGKVQIEIFEKTVEHRLEDPTFITAYPTEVSPLARRNDEDPFVTDRFEFFVGGREIANGFSELNDPEDQAERFRRQVEEKEAGDEEAMHFDADYIRALEHGLPPTAGEGIGIDRLVMLFTDSPSIRDVLLFPHMRPES
>NZ_AP012978.1|WP_043108058.1|1560765_1561725_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MNLDFLDFEQPIAELQAKIEELRLVGTDNEINIQEEIEKLEGKSRSLTESIFAKLTPWQISQLARHPLRPYTLDYIERIVDDFEELHGDRAFADDYAIVGGLGRIDGRAVMIIGHQKGRDTTEKIYRNFGMPRPEGYRKALRLMKLAERFRIPVVTFIDTPGAYPGIGAEERGQSEAVARNLWEMSALRTPIVATVIGEGGSGGALAISVADKLMMLEYATYSVISPEGCASILWKDAEKAPLAAEAMAITSKHLKSHGLIDEIVPEPLGGAHRDPEQMARSLRNVLVQTLDNLAAEPLDRLLEHRYERLMSYGMVANG
>NZ_AP012978.1|WP_082000002.1|1559394_1560732_-|tRNA-lysidine(34)-synthetase-TilS
MYRLSPLPAPTGWLIAFSGGLDSSVLLHAAAALRERLAGPLRAVHVHHGLQPEADQWAAHCRTVCARLEVPLEVLHLHLEIPAGESPEAAARAARYRAIAGVLRPGEMLLLAQHRDDQAETLLLQLLRGAGVAGLTGMPRCRRWASGWQARPLLDFSRAALRQWAETRGLDWIEDPSNADLRFDRNFLRHRVLPLLRERWPGADKALARSAALLGETRDLLDDCVAGALAGCRAGSGLSVAALRELAVPMRAEVVRAWLRDGGWPLPDQGRLQTIDRQLIESEAGTAPQVAWADVSLRRYRGCLYAVPNPLPAPPTGERVWPAPTPLDLGPGRGRLLALPAARGIPVHCWEAGRVRVRWGESGWRCRPPGRRGHRSARKLYQELGVPAWVRPHVPLIFVDERLVAVGGFSLCELPLARPGEICYRPAWREAVVWPPTGEEDDGIS
>NZ_AP012978.1|WP_171816211.1|1558898_1559408_-|paraquat-inducible-protein-A
MGFRDSHAAHHPVQGLLVNLLLVAALVLLLIGLRTPLLTVEQFYFFRNTVSLWSGLQQLRAEGEWGLFVLIGAFSVVFPVVKILLLALVWNFGREGCRAHARHLHWLAEYGRWSMLDVFVVALIVVTVKLGVLAQARVEPGIYWFSASVVLTMLLAHWIGHHANGAASR
>NZ_AP012978.1|WP_043108056.1|1556281_1557748_+|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase
MSSVLLPVILSGGAGTRLWPLSRRAFPKQFHNLVDDLTLLQTTALRCDGLSGHEVAAPLVVCNEMHRFLVADQLLACGRPASGILLEPVGRNTAPALTLAALHATREIGDPVLLVMPADHVIRDEQAFTRALETGVHQAADERVVTFGIVPQTAHTGYGYIRQGEALDDGVHQLDAFVEKPDQETAERYLRDGGYLWNSGIFMVRATRWLELIESFAPEIHQTVTAAHAGGRQDLDFVRVDAEAFAACPSDSIDYAVMEPLSRQGGDCVVVPLDAGWSDIGAWEALWEVSHQDEQGNAIHGDVMTLDAQNNLLFSQHRMLAAVGIKDLVVVETPDAVLVADKSHAQEVKQIAERLQAEGRRPKAEGRSEHEFHRCVHRPWGTFEGIDQGHRFQVKRLTVKPGASLSLQMHHHRAEHWIVVRGTARVTRGDETFLLTENQSTYIPIGTRHRLENPGQVPLEIIEVQSGSYLGEDDIVRFEDVYNRRDET
>NZ_AP012978.1|WP_082000001.1|1555350_1555857_-|DUF2173-family-protein
MNQPGVIAAGEYSYRGDRFSYKGEIDEEMARMASIMCRATTMSEHMQVGMLEQFCPGCGSSPPHGWIVRGPMFTVCNVANVYAFLHNQTASLNDIMALMQKRLADEAIDTGVMGTETTLSKATLSGPQGVHPRCCSGLTWNHHACCLCALWLNALRPAQGERSERCFT
>NZ_AP012978.1|WP_043108066.1|1571922_1572558_+|pyridoxamine-5'-phosphate-oxidase
MDIADLRREYQYAGLSRKDLDPDPFRQFERWFIEARDAGLNNPNALSLATCGTDGMPSVRTVLLKAFDHHGFVFYTNYGSRKAREIEANPKAAMLFHWLELDRQVKIQGAVERVSTRESLAYFRSRPRGSQLGAWCSDQSRPVASRTLLEQAFESMKRKFRDGDIPLPDFWGGYRVIPERIEFWQGRENRLHDRFEYQQAGDGWEIRRLAP
>NZ_AP012978.1|WP_082000003.1|1572757_1573000_-|transposase
MTAARLSHLPEVRGKDLAAELDIHPFMLSRGRKEYREGKLEGDVKKPIDPQTAAELKRLRKLERDYAWLKEEHEILKKAI
>NZ_AP012978.1|WP_171816212.1|1574062_1574380_-|membrane-protein-insertion-efficiency-factor-YidD
MTDLVANRLLIRAIVFYQHSMSSKKGYKCAYGVVHGTHTCSSYGLRIARRYGWKYFLPLIKRQHERCHQAAMGYEESPSSQSSEDGETQKECKEVVGCCGASWPF
>NZ_AP012978.1|WP_148307701.1|1574376_1574910_-|hypothetical-protein
MAAVVGGVTGRLGGGKFANGAVSAGFAYLFSGGMSAANDERYGSDEIQLPTVKELLDGGQLLADNYAPNGYGLLNDRTDIDEVLVCDHRNRTAMYVNKTVAAQAQMQVDMNADSLGIQIDTRTQAQRDYDACVLTCMMSSGLVGGPINKIIKGGLYGAAAGYGGRKTFCQHMGCPKP
>NZ_AP012978.1|WP_082000004.1|1574908_1575265_+|pyridoxamine-5'-phosphate-oxidase
MLFHWLELDRQVKIQGAVERVTTRESLAYFRSRPRGSQLGAWCSDQSRPVASRTLLEQAFESMKRKFRDGDIPLPDFWGGYRVIPERIEFWQGRENRLHDRFEYQKAGDGWEIRRLAP
>NZ_AP012978.1|WP_148307702.1|1575628_1576138_-|hypothetical-protein
MTLQGISKLAGVFVTFGFIVSVIYDWGFFRSLGIEYRHVPSSIADHFRTGLLWFPPLVGSFIFYLAWEFQVQRIEKGLTEDEIVSGSKDPEKTRKMRNAPYKFFVWICILMVLGYILIGDIASSVPTVAFSVLWLIFADWCYSTPLIQLRRSEWVQSSFKFLPAAAILA
>NZ_AP012978.1|WP_081999879.1|1576241_1577267_-|YaaC-family-protein
MSCHKLHIAGKAVRLHSALIGADFRKPRVLCTDPWEFVSLWLKRDHQTDAAFYWAQAHHFYDASLSLPVLSSPLTSYYCFLNTTKALLTAKKVEFKEVHGVGGRSVGSVKSLDNEIVDFQGGGILPALCKYLEEPDNAGKEFTLKDIFWQLPFIHRSFCLTYRGSTELFIPLVNQCFLRRDGSKEAWFHAEIDKRYINSHTKRVIQPGFELFDNNGVYEIRRKRRFKWSGRDIENSIEQFSRYHKQIRRRIFPIYSSENRWYLKKSVNGHDKLNNSQLVLIFAAMHRLSELSRYDPIPFSKHFNVNHNWLLSEFIKASLGQFVYGMASEITGLEFIKPDAF
>NZ_AP012978.1|WP_148307703.1|1577379_1577661_+|hypothetical-protein
MSDRESAPEDPRVARFWRAYLETLRLFRVPERAPPWYRHHVESFMRANLGVRLREQTTEKVGDWLEAQGRYPRKRLPVFPWRQGSLCRRRVGN
>NZ_AP012978.1|WP_043108069.1|1577948_1578188_+|hypothetical-protein
MPHVIVDPESTALAERWALIKTPRKNRKRYPEACVQVCESEADAREGADAKRNLHPAIVYGPSVSSESQRIYYLVRWLD
>NZ_AP012978.1|WP_081999880.1|1578675_1579164_-|regulatory-protein-RecX
MRAEGELPFGEDEEVADPASEIEAAAVRLLAGREHSRHELANKLGRRFDRETVEAVLDELVERGLVSDDRFTEHYVASRMRKGFGPLRIRAELRERGIDGDLIEAWLDLGDDTWREHLHEVARGRFGDERPADRRAQAKQARFLQYRGFPESLIRDYLWGSA

Crispr_ID: NZ_AP012978_10

• CRISPR_ID: NZ_AP012978_10
• CRISPR_location: 1814037-1814141
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP012978_10

Consensus_repeat	Method
GTAGGAGGCCCGTCCCCGGGCCGAACCTACGCGGC	CRISPRCasFinder

spacers of NZ_AP012978_10

>10.1|1814072|35|NZ_AP012978|CRISPRCasFinder
AGATCATTCACGGCGAGGACGTCGATCCTACAGCC

CRISPR arrays and Neighbor proteins around NZ_AP012978_10

CRISPR arrays

The CRISPR arrays of NZ_AP012978_10

>merge|NZ_AP012978|10|1814037-1814141|CRISPRCasFinder
GTAGGAGGCCCGTCCCCGGGCCGAACCTACGCGGCAGATCATTCACGGCGAGGACGTCGATCCTACAGCCGTAGGAGGCCCGTCCCCAGGCCGAACCTACGCGGC

>NZ_AP012978|10|9|1814037-1814141|CRISPRCasFinder
GTAGGAGGCCCGTCCCCGGGCCGAACCTACGCGGC	AGATCATTCACGGCGAGGACGTCGATCCTACAGCC
GTAGGAGGCCCGTCCCCAGGCCGAACCTACGCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_043108287.1|1810157_1810409_-|hypothetical-protein	unknown	unknown	gnl|CDD|274226
NZ_AP012978.1|WP_052199440.1|1815774_1817874_-|carboxy-terminal-processing-peptidase	unknown	unknown	gnl|CDD|236873
NZ_AP012978.1|WP_043108291.1|1812273_1813029_-|flagellar-motor-protein-PomA	unknown	unknown	gnl|CDD|181604
NZ_AP012978.1|WP_043108293.1|1817870_1818743_-|DUF4743-domain-containing-protein	unknown	unknown	gnl|CDD|178432
NZ_AP012978.1|WP_052199442.1|1824042_1827336_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NZ_AP012978.1|WP_171816224.1|1828631_1829060_+|DUF3592-domain-containing-protein	unknown	unknown	gnl|CDD|378822
NZ_AP012978.1|WP_043108284.1|1804346_1805003_+|DUF971-domain-containing-protein	unknown	unknown	gnl|CDD|226066
NZ_AP012978.1|WP_148307714.1|1827769_1828309_+|NYN-domain-containing-protein	unknown	unknown	gnl|CDD|350235
NZ_AP012978.1|WP_052199439.1|1810756_1811392_-|PilZ-domain-containing-protein	unknown	unknown	gnl|CDD|377796
NZ_AP012978.1|WP_043109566.1|1822829_1824038_+|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_AP012978.1|WP_043108290.1|1811411_1812272_-|type-VI-secretion-system-protein-TssL	unknown	unknown	gnl|CDD|236356
NZ_AP012978.1|WP_081999895.1|1806122_1808291_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|182070
NZ_AP012978.1|WP_043108295.1|1821100_1822459_-|dNTP-triphosphohydrolase	unknown	unknown	gnl|CDD|234897
NZ_AP012978.1|WP_043108294.1|1820304_1821099_-|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl|CDD|236569
NZ_AP012978.1|WP_043108288.1|1810484_1810760_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_082000008.1|1814151_1815699_-|glutamate--cysteine-ligase	unknown	unknown	gnl|CDD|235001
NZ_AP012978.1|WP_171816223.1|1818753_1819773_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|227122
NZ_AP012978.1|WP_070104732.1|1804926_1805445_-|dihydroneopterin-triphosphate-diphosphatase	unknown	unknown	gnl|CDD|236516
NZ_AP012978.1|WP_081999894.1|1802907_1804269_+|HDOD-domain-containing-protein	unknown	unknown	gnl|CDD|370050
NZ_AP012978.1|WP_043108285.1|1808297_1810079_-|aspartate--tRNA-ligase	unknown	unknown	gnl|CDD|234775

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_043108287.1|1810157_1810409_-|hypothetical-protein	gnl|CDD|274226	TIGR02605, CxxC_CxxC_SSSS, putative regulatory protein, FmdB family. This model represents a region of about 50 amino acids found in a number of small proteins in a wide range of bacteria. The region begins usually with the initiator Met and contains two CxxC motifs separated by 17 amino acids. One member of this family is has been noted as a putative regulatory protein, designated FmdB (SP:Q50229, ). Most members of this family have a C-terminal region containing highly degenerate sequence, such as SSTSESTKSSGSSGSSGSSESKASGSTEKSTSSTTAAAAV in Mycobacterium tuberculosis and VAVGGSAPAPSPAPRAGGGGGGCCGGGCCG in Streptomyces avermitilis. These low complexity regions, which are not included in the model, resemble low-complexity C-terminal regions of some heterocycle-containing bacteriocin precursors. [Regulatory functions, DNA interactions].	1.14113e-22
NZ_AP012978.1|WP_052199440.1|1815774_1817874_-|carboxy-terminal-processing-peptidase	gnl|CDD|236873	PRK11186, PRK11186, carboxy terminal-processing peptidase.	0
NZ_AP012978.1|WP_043108291.1|1812273_1813029_-|flagellar-motor-protein-PomA	gnl|CDD|181604	PRK08990, PRK08990, flagellar motor protein PomA; Reviewed.	3.06553e-117
NZ_AP012978.1|WP_043108293.1|1817870_1818743_-|DUF4743-domain-containing-protein	gnl|CDD|178432	PLN02839, PLN02839, nudix hydrolase.	6.33274e-76
NZ_AP012978.1|WP_171816224.1|1828631_1829060_+|DUF3592-domain-containing-protein	gnl|CDD|378822	pfam12158, DUF3592, Protein of unknown function (DUF3592). This family of proteins is functionally uncharacterized.This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 150 and 242 amino acids in length.	4.5441e-15
NZ_AP012978.1|WP_043108284.1|1804346_1805003_+|DUF971-domain-containing-protein	gnl|CDD|226066	COG3536, COG3536, Uncharacterized protein conserved in bacteria [Function unknown].	5.6761e-37
NZ_AP012978.1|WP_148307714.1|1827769_1828309_+|NYN-domain-containing-protein	gnl|CDD|350235	cd10911, PIN_LabA, PIN domain of Synechococcus elongatus LabA (low-amplitude and bright) and related proteins. This subfamily contains Synechococcus elongatus PCC 7942 LabA which participates in cyanobacterial circadian timing, it is required for negative feedback regulation of the autokinase/autophosphatase KaiC, a central component of the circadian clock system, and appears to be necessary for KaiC-dependent repression of gene expression. This subfamily belongs to the LabA-like domain family which includes the N-terminal domain of limkain b1, a human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes. Also included in the LabA-like domain family are human ZNF451, uncharacterized Bacillus subtilis YqxD, uncharacterized Escherichia coli YaiI, and the N-terminal domain of a well-conserved group of mainly bacterial proteins with no defined function, which contain a C-terminal LabA_like_C domain. Curiously Pseudomonas putida S16 NicB , which is described as a putative NADH-dependent hydroxylase involved in the microbial degradation of nicotine also falls into the LabA-like family. The PIN (PilT N terminus) domain belongs to a large nuclease superfamily. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.76929e-21
NZ_AP012978.1|WP_052199439.1|1810756_1811392_-|PilZ-domain-containing-protein	gnl|CDD|377796	pfam07238, PilZ, PilZ domain. PilZ is a c-di-GMP binding domain which is found C terminal to pfam07317. Proteins which contain PilZ are known to interact with the flagellar switch-complex proteins FliG and FliM. This interaction results in a reduction of torque generation and induces CCW motor bias. This domain forms a beta barrel structure.	1.20134e-06
NZ_AP012978.1|WP_043109566.1|1822829_1824038_+|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.09024e-36
NZ_AP012978.1|WP_043108290.1|1811411_1812272_-|type-VI-secretion-system-protein-TssL	gnl|CDD|236356	PRK08944, motB, flagellar motor protein MotB; Reviewed.	2.00093e-123
NZ_AP012978.1|WP_081999895.1|1806122_1808291_+|EAL-domain-containing-protein	gnl|CDD|182070	PRK09776, PRK09776, putative diguanylate cyclase; Provisional.	3.22492e-150
NZ_AP012978.1|WP_043108295.1|1821100_1822459_-|dNTP-triphosphohydrolase	gnl|CDD|234897	PRK01096, PRK01096, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	5.98074e-151
NZ_AP012978.1|WP_043108294.1|1820304_1821099_-|nucleoside-triphosphate-pyrophosphohydrolase	gnl|CDD|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	2.34845e-128
NZ_AP012978.1|WP_052199442.1|1824042_1827336_+|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_AP012978.1|WP_082000008.1|1814151_1815699_-|glutamate--cysteine-ligase	gnl|CDD|235001	PRK02107, PRK02107, glutamate--cysteine ligase; Provisional.	0
NZ_AP012978.1|WP_171816223.1|1818753_1819773_-|tetratricopeptide-repeat-protein	gnl|CDD|227122	COG4783, COG4783, Putative Zn-dependent protease, contains TPR repeats [General function prediction only].	3.45672e-16
NZ_AP012978.1|WP_070104732.1|1804926_1805445_-|dihydroneopterin-triphosphate-diphosphatase	gnl|CDD|236516	PRK09438, nudB, dihydroneopterin triphosphate pyrophosphatase; Provisional.	4.58669e-52
NZ_AP012978.1|WP_081999894.1|1802907_1804269_+|HDOD-domain-containing-protein	gnl|CDD|370050	pfam08668, HDOD, HDOD domain.	0.000841493
NZ_AP012978.1|WP_043108285.1|1808297_1810079_-|aspartate--tRNA-ligase	gnl|CDD|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0

Protein sequences

>NZ_AP012978.1|WP_043108291.1|1812273_1813029_-|flagellar-motor-protein-PomA
MDIATLVGLLGGFGVIIGAIASGGDVMMFVDVPSVLIVIGGTFMVTLMQVSLGDFLGSFAVGMKAFFYKVDDPKKLIEEGVALADIARKNGLLAFEGQEISNDFMKRAISLCVDGHDPALVQRMLSKEIDQMLERHEVGISMFKNMATMAPAMGMIGTLVGLVQMLANMSDPAAIGPAMAVALLTTLYGAVIANAFAQPMADKLARATAIERTNKSLIMETIAGLQEGMNPKVLEQLLSTYLPKKKRPGDE
>NZ_AP012978.1|WP_043108290.1|1811411_1812272_-|type-VI-secretion-system-protein-TssL
MADKCPPCEEGLPAYLATFADLMSLLMCFFVLLLSFATIDAIRFKKMAESMKDAFGVQREIPAAEIVKGVSVIKQEWSPSVSEQSVINEVRQETSDVEKENLKMNDGEMDAEQAMKLADQIIEKELQGQMAELQEALKEQIDQGLISLDKEEKKIIIRIQEKGSFGSGSARLDPGFYKVIDRISEVLATRPGKILVAGHTDNIPIRTGRFRSNWELSSVRAVTVLHALLRNPRLDQRRVVVQGFADTRPVADNDTPQGRAKNRRVELIILRGRDHENGEKITIPTD
>NZ_AP012978.1|WP_052199439.1|1810756_1811392_-|PilZ-domain-containing-protein
MHRNEDKQTANERREYFRVDDAVRLSLRPVPPEQAQNLSELLEGNLADSFTIMSSLAAVTAEMVVNMRRIENSDPDVAAYLKALDRKIEILGRAFIACESELAEQPAHPVNLSAGGMAALVNECYQPGQLVEIRMLLFSSFTGVLMYGTVVACDPVEAEDKGAGYSHRVRMAFTHLREQDRDIVIRHVLRCQSQALRGQGQRGDGDPADDA
>NZ_AP012978.1|WP_043108288.1|1810484_1810760_-|hypothetical-protein
MIKPSEEALEKALAAAQRMRANDVDPHHLAQAVLYLHERNQRLEEVLKYTERFIRFGMAEPELAQLRRLVQRLREEGGRQEGGDPDTSMLL
>NZ_AP012978.1|WP_043108287.1|1810157_1810409_-|hypothetical-protein
MPFYEYRCAECGHEFEAMQKMSDAPLRDCPECGKPALDKLISAAGFQLKGSGWYATDFKGGSCGKPADEAPACGTGGACPACE
>NZ_AP012978.1|WP_043108285.1|1808297_1810079_-|aspartate--tRNA-ligase
MRTHYCGEINADFIDQTVELCGWVNRRRDHGGVIFIDLRDRSGVVQVVYDPDVEDVFATAEQVRNEFVLRIKGRVRARPEGTVNPDLPTGEIEILGKELEILNRAETPPFQLDDEDTSEELRLRYRYIDLRRPVMQERIQLRARVTRALRRYLDEQGFLDIETPMLTRATPEGARDYLVPSRVHAGKFFALPQSPQLFKQLLMMSGMDRYYQVVRCFRDEDLRADRQPEFTQLDLEMSFIDEEQIMSLMEEMIRGVFRETLGVELPDPFPRMSYAEAMRRFGSDRPDLRCSLELVDVADLLTDIEFKVFAGPAKDPKGRVAALRLPGGGRLSRKEIDDYTKFVGIYGAKGLAYIKVNELANGVNGLQSPILKFIPDEAVMEIMARTGAEDGDIVFFGADKAQVVNEALGALRVKLAEDLGLMEEGWRPLWVVDFPMFEWDEGSDRWHALHHPFTAPKADQIDLLESDPGACLSRAYDMVLNGTEVGGGSIRIHQEAVQEKIFSLLGIGEEEAREKFGFLLDALKYGCPPHGGLAFGLDRLVMLMAGAHSIRDVMAFPKTQSASCLLTQAPSEVSTEQLRELHIRVRTQGKKSG
>NZ_AP012978.1|WP_081999895.1|1806122_1808291_+|EAL-domain-containing-protein
MSAPPPRLSISVQPLEIEDAPSCLLEVTPLIADQGKRVMATQAHRIIENIRDVIITLDDRQRIVDMNRAAHELLGLDDAQILGAHIHTILPGLSLDQVLADDNSNRQLTAIHGSGRHFPAEISVSQIECDVASFTLLILRDLTAQKETEETLHREKEFAQITLQSIHEAVITTDARGRINSVNRAACRLLRRNEDGIVDRLLADLLRFTGLDHRRKVREYLKSTLEHGHSNEIDGQPEIRFDDHESIYISGRIAPLRSAAGEIIGSVVVLQDVTSEKRMREILSWQASHDDITSLINRREFERRLQALIADRPGNARHVLLYLDLDQFKLINDNCGHDAGDQMLRQLTSRLGTRLRETDTLARLGGDEFAVLLPYCDVEDGRRIAEELRELIRSFRFDWEGRTFGVGVSIGLVLIDRHILSVTDALTAADSACYIAKEGGRDQVVVYRPEGNEEQRRREEISQTALIREALEQDRFCLWAQPILPIQHNSGDWGAEVLVRMIGEDGRIIPPGAFIPGAERYHLMTRIDRWVVRAVCKHWKTNPASFKRLDKIAINLSGQSIANNEFLEFLIREIERFRIPWGSLCFEITETAAITSIKKARYFIQTLRDHGARFALDDFGSGLSSFAYLKHLPVDYLKIDGAFIKDMEHDRIDAAMVRSISEIGRAMQLRTIAEFMENERVVHMLREAGVDFVQGYGICRPMPIEELAAYEPQAPGLSLASG
>NZ_AP012978.1|WP_070104732.1|1804926_1805445_-|dihydroneopterin-triphosphate-diphosphatase
MTFRRPESVLVLVCNDRGETLLLERRSPAGFWQSVTGGLRRGESLRMAARRELFEETGFDHAVPLFDLREQRRFPIVPPWRARYAPEVHSNLEHGFLACVRGRRIPRLRPAEHVRWRWLPAREAAQRVFSWTNREAIERHAEACRAGVTSSVGQAGWASWAQWPPRRRDRGG
>NZ_AP012978.1|WP_043108284.1|1804346_1805003_+|DUF971-domain-containing-protein
MSENEHPVPTEINLHRKSRLLNITFSDGQSFSYPCEYLRVYSRAAEEVTRDAPVMGKEQVNIERIEPQGTYAVRIVFDDGHDTSIYSWETLYDLGIHQERYWQDYLERLAAAGYSRQGDRLGDQPEAQRRITVLYFNYLARMMRREAEELTPPPSVTDVDSLLTWLQKAKGERGYLLAPEHVRVTVNKQFAEPFTRLDPGDEVAIVPNSPNPPAPPKK
>NZ_AP012978.1|WP_081999894.1|1802907_1804269_+|HDOD-domain-containing-protein
MSRRLSTLSRARPPIMPETARRVRALLASPRSTYQDLEAVLLCDPAATLALYRAAERLRRGTVDELTGPAHALSLIGREAFRRAFEQLPVLDRPPLQHILSPAFAASQVAHAGWYAEQIGRVMGFSHPVEMRVAALLQHPAVLALWATDFEAAARATNAMRDGVSFSVAFTAELGQPLKKVNRRLAAEWTLPRLAREVISDWDPANRLPQSVSLASRLALVGAAGWPEEEHRLHIEVLAGLLPHHHHDAAAWWHRQAVEAARVLHPFGYPLAARELILLPGGEHEVEVPALRGRDYRRTPSRQATGRLQQLLGSQLREIRQACGVDRILLAMPDRERKSLRARLVIGGPPDSPMRKLALPLRARHLFSLLLTQPRAVWVRAENREKYLPLLRPLPLDAQSAGGFFAMSLFVEQRPLGVLFADGGKLDDVAFRAFREAGQRLAEHIRALRRQAA
>NZ_AP012978.1|WP_082000008.1|1814151_1815699_-|glutamate--cysteine-ligase
MSPEVIRQTRMGLEKESLRVARDGGIATTPHPRAWGAALTHPWITTDYSEALAEFITPPLASSGAALDFLADLQSYAYRRLEGEFLWATSMPCILAGGQSIPIAEYGDSNLGRMKHVYRVGLGWRYGRVMQVIAGVHFNWSLSESFWPAYAQLLGEPDADALRNDAYMGMVRNLQRIGWIVPYLFGASPAVCKSFFADGTSHLSVFDEDTFFEPYATSLRMGDIGYQNKKEDGLGIHVCYRDVATYAQSLLYAVTTPAEAWERIGVKVDGEYRQLNANLLQIENEYYNTVRPKQVLGRMEVPAVALLQRGVRYVELRSLDVNAYHPLGVDETQLRFLEALMFACLLADSPGLSGDELLEINENILRVAHRGREPGLKLRCCGDPVRLYDWGQRIMDAVMPVAEFLDRLHGDHRYEDAVDDQLRKLMHVDLTPSARMLDEMGERGESFYQFARRLSTAHHRYFRERALAPERVDEFDRLVEQSFADQASLETTDDRDFDSFLAEYFAQTYQALETA
>NZ_AP012978.1|WP_052199440.1|1815774_1817874_-|carboxy-terminal-processing-peptidase
MSRTFDRILVVLGVLWCLGAWARPQTVAVESLHADEQQRRTALVIAQVLEGFHYTRPHIDDHLSHDAFERYLETLDPNRSFFTQQDIARFEAYRDRFDDALVKGRLEVPFEIFRLFRHKVEQRAAYAIDLLNNHDFDFSRDEEYVFDREDQPWVRDEVELDDLWRKRVKNDILIERLSDKPFELEKLVKRYEGMRDRVQQMNAGDVFQAFVNAITLSIEPHTSYMSPEVSENFDIGMRLSLQGIGAVLRSEDGYTKIIRTVVGGPAARSGKLHPGDHIVGVAQGRDGPMEDVVGWRLQDVVELIRGPKGSVVRLNVIPKSEGIGGRAREVVLVRDTIKLEDKAAKAKVLEGPEYGGLKIGVIDIPAFYRDFAAQAAGKRNFRSTTRDVRRLLLDLEQQGVDGIIIDLRQNGGGSLTEAAELTGLFIDKGPVVQIKDAAGHVELERDRDPGEVYDGPLVVLVDRNSASASEIFSGAIKDYGRGLIVGEPTFGKGTVQTLVNLARYLRSNEDLGRLRLTMAQFFRVLGASTQHRGVEPDIEFPTAMGATDHGERALEHAIPWAAIQPVIDPPRTTFPVAWLREQSEKRIRGNPGFRYLIDREREFMKIREVKSASLNEQTRRAEREAREQRLLALRNRLRTWRGLPPLERLDEEDEDERLAHADEDPEGVDRIMLEETAHILADWIRASRPLTVQVTEHDR
>NZ_AP012978.1|WP_043108293.1|1817870_1818743_-|DUF4743-domain-containing-protein
MSYLRHIRACNAPVTEPFLPWYIDGRVHGWIRPALAAHLADWPDLFERRDQALHTPSAMVPELTGRLTEVARELAARGVVTALLDEPYPVTADGREQAVATVDRALAAPLGLRSFGQHLNGYVRDGGRILMWIGRRARDRLIFPGALDQLVAGGLPHGVDLWENLVKECAEEAGMPEALARRARPVGALTYNRVAERGFRPDVLYCYDLELPVDFVPRNTDGEVEEFLLLPLEEVARIVRETDEFKLNCNLVIIDFLVRHGVIGPDDPDYLAIVIGLHPAVGMPETSRGL
>NZ_AP012978.1|WP_171816223.1|1818753_1819773_-|tetratricopeptide-repeat-protein
MKSRFSREAESEADVYGMRYMVRAGYDPAAAVSLQETFVRLFEDKSPGWLAGLFASHPPSRERVAANRRLLAELGNPGGERGRERYQRAIAHLRQVQPAYEAYAQARKALDAGDMQRALGLVDKAMRIEPKEALFPTLRGEIHKRRGRRREALRDFDRALALNPDYYLPRVQRSLLERELGRQTAAERDLEASIALLPTAEAYYGLGLIAEQRGRTREALGYFQAVATSESEMSKDAARRLALLDLADHPDSYLKASLGLRKDGRLLLRLRNASAVPVRGIRVVIGRPVGRRFEPLRTLRLRGRLPAGREQRLDTGLQLRDAAEARGLVARVIAARPVR
>NZ_AP012978.1|WP_043108294.1|1820304_1821099_-|nucleoside-triphosphate-pyrophosphohydrolase
MAGGGEAVEALLELMARLRDSQDGCPWDRAQDWHSLIPYALEEAYEVADAIEQDDPDALREELGDLLFQVVFYAQIAQEAGQFDFAEVARGITEKMVRRHPHVFGDSTARDADSLHRAWEAAKAAERADKTEDASRLEGIARALPALVRAHKLQKRARDAGFDWPDPAGAHAKVHEELTEVAQAAEAGDADHLEEELGDLLFAVVNLVRLHGFQAEHTLRRANDKFERRFRAMERRLAAAGHQDLDALSLEQMEAAWPAVKEEE
>NZ_AP012978.1|WP_043108295.1|1821100_1822459_-|dNTP-triphosphohydrolase
MQWPRLLSRKRLGSDAEPSLSTARTDFQRDFDRVVFSSAFRRMQDKTQVFPLSKVDYVRTRLTHSLEASCIGRSLGTLVGEQVIARHGLHDFESADFGNICAAACLAHDIGNPPFGHSGEDAIRHWAESADYGARRVAGLRGSQREDFLAFEGNAQGFRIVTRLQNPDNPGGLQLTCATLAAFTKYPRESCLAGNRFEGVSARKQGFTAADRESFEQVAKEVGLLRRDERYAIWYRHPLAFLVEAADDIAYRVIDIEDGYRLGHFSYDEVTGAFLDLLPDRERQAARLGGIREPKDRIEFLRAKVINQVIEQALACFMDNEQDIRAGRFDRPLLDEIPARAQADVLIEMACQRIYCAPEVVSIQAAGFQVIHDLLERFVQVLDDVAEHGEQASPRSQMLIRLIPEQFIGHHRVPSPDPYLRLLMLTDFVSGMTDSYAVSLYKKVTGISLPGG
>NZ_AP012978.1|WP_043109566.1|1822829_1824038_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MRTLSLLAAVGLALAVQVSPAAEPTATPDLRIVPVERRQADLTVSIAATITPFRTVQLTAQTPGRVKHIAGREGDAFVRGAVLIELDDAALLARRESAFAARESALAAIQSAQAQYQQELYSPRSDAVRTAPGGFGFPAMMDQMFGVPMQDALGLREQGVQRYTDMIDVQTRLAQARNQLRQADASIREIDAQLRDTRSVAPFDGVIDKVHVEEGDTVQPGQPLVDYSQAGLFKVEADLPVHLARHLMPDQALPVRLDNGGEPVSVRVRRIHPSADLRRHTIHVELALPPGAHATAGQYAEVLVTDRGAEVTAQLAIPTSAVIRKGGMPLVFSVDEQGIAHLRVVRLGEELAQGQVAVLSGLHEGDRVIDQPPAGLKAGRQVIASEAPADPATPAPNTANEG
>NZ_AP012978.1|WP_052199442.1|1824042_1827336_+|efflux-RND-transporter-permease-subunit
MPGEISVNKHQQLGLAGAIARSFIHSPLSPLLFLAMLGMGIIGLIATPRQEDPQISVPLVDIFLAYPGASAEQVAAKGIEPLERIMSEIPGVKHVYSASMREQGIVTVRFRVGEEAGPSIIKVHDKLASHLDRIPPGIQGPPLVKVKGIDDVPIVTLTLWSRELDSANLRKLANNVLQQLKQIPDTGQGFIVGGQHDQIRIQIRPEKLSSHGVTADEIVARIRHANLERRVGRGEQDNHDFRIYAGAFLRTPQDVQNLVLRVEDGAPVYVRDVAEVSWAPEETRHYVNYFTGPATAASLADERIADGENAITIAIAKKQGSNGVTAAEAILERMEMLKGDLIPEQVEVAVTRNYGQTAADKVNALLMKLVIATGIVTLLVWWTLGFKPALVVTIVIPVVILMTVFAAFVMGFSIDRVSLFALIFSIGILVDDAIVVVENIYRRWLLKGEPSTEIAIDAVREVGNPTIVATFTVVAALMPMAFVRGLMGPYMAPIPVLGSVAMIISLFAASAFTSYLVMRIRPSMARLEQAEGKEHATNARLERLFRRILPPLLDNRLLGYGFLFALIGAFFAVCALFYTTAVTVKMLPYDNKPEFAVVIDLPEGTALPVTANVAREMAETLRGIDEVTALQTYAGTARPFDFNGMVRHYYLREQPWQAEIQVQLVDKHARSASIHELAERARALLKPIADAYGAHITVAEMPPGPPVLQSVVAEIYGPDAETRREVARHMTEVFEQTEGMADVDNYMTEPHASWRFVINAQKASTKGVTTARIVENLAMVMGEYKITDRRTDNALEPTWITIQAPLALRANPQALGDLPIAAPGGVTIPLAELGHWERISEDPIIYHKDLRPVEYVVGDAVGRLGAPIYPMMKIDEALQDYVTPDGQTLSGTMTGPPPANGLSGFEWAGEWTVTYETFRDMGAAFGVALVLIYMLVVGMFGNFTVPAIIMAPIPLTLLGIVPGHWIITQITGTNAYFTATSMIGFIALAGIIVRNSILLVDFAVEEIRCGRDVREAVLLSCKARTRPILITAFALIGGASVILFDPIFQGMAISLMFGVFVSTLLTLLVIPLGCVSAARSMRAIADARDTKGAPRAI
>NZ_AP012978.1|WP_148307714.1|1827769_1828309_+|NYN-domain-containing-protein
MEVSRIVWIADAGYLIKACPGKFDYLKLKELLESECGGTFAESFYLNSTPYPPTDAQDSFHSWLKTAPPRGPKMRVKLYKLKDMHHQCPNCNHSFDRPVQKGVDVGIATLIVKLAAQDQYSRLILSAGDGDFEDAIAFAKEELHKEIWISGFPESLSPDLQSYADKVIWLDEHWDAFKK
>NZ_AP012978.1|WP_171816224.1|1828631_1829060_+|DUF3592-domain-containing-protein
MKSLLGIFFLIGACLLGVDLLAGIKMLNAQSWPRADGTIESSSFVLAGSKPSTTSEKVSYSYQVDGKIHENDRIYFGMVISSRNKPLSYRKGEHVYVFYNPDDPSESVLRTDDTHSVIFVGFAGMAFIGFSLFGYWLERRKA

Crispr_ID: NZ_AP012978_11

• CRISPR_ID: NZ_AP012978_11
• CRISPR_location: 2287928-2288020
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP012978_11

Consensus_repeat	Method
GTTCGCGGCGAGGACGCCGCTCC	CRISPRCasFinder

spacers of NZ_AP012978_11

>11.1|2287951|47|NZ_AP012978|CRISPRCasFinder
CTCCCTGTAGGAGGCCCGTCCTCGGGCCGAACCTCACCGGGCCGAAG

CRISPR arrays and Neighbor proteins around NZ_AP012978_11

CRISPR arrays

The CRISPR arrays of NZ_AP012978_11

>merge|NZ_AP012978|11|2287928-2288020|CRISPRCasFinder
GTTCGCGGCGAGGACGCCGCTCCCTCCCTGTAGGAGGCCCGTCCTCGGGCCGAACCTCACCGGGCCGAAGGTTCGCGGCAAGGACGCCGCTCC

>NZ_AP012978|11|10|2287928-2288020|CRISPRCasFinder
GTTCGCGGCGAGGACGCCGCTCC	CTCCCTGTAGGAGGCCCGTCCTCGGGCCGAACCTCACCGGGCCGAAG
GTTCGCGGCAAGGACGCCGCTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_043108719.1|2291376_2293011_-|chaperonin-GroEL	unknown	unknown	gnl|CDD|234573
NZ_AP012978.1|WP_043108717.1|2290163_2291282_+|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl|CDD|369642
NZ_AP012978.1|WP_043108725.1|2295025_2295571_-|DUF1415-domain-containing-protein	unknown	unknown	gnl|CDD|377792
NZ_AP012978.1|WP_043108715.1|2288229_2288820_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_AP012978.1|WP_052199541.1|2278538_2279819_-|phosphate-regulon-sensor-histidine-kinase-PhoR	unknown	unknown	gnl|CDD|274368
NZ_AP012978.1|WP_043108724.1|2294160_2294901_-|TSUP-family-transporter	unknown	unknown	unknown
NZ_AP012978.1|WP_043108710.1|2282073_2283369_-|phosphate-ABC-transporter-permease-PstA	unknown	unknown	gnl|CDD|223654
NZ_AP012978.1|WP_043108722.1|2293530_2294127_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043108714.1|2285920_2287873_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|236729
NZ_AP012978.1|WP_043108708.1|2279811_2280489_-|response-regulator	unknown	unknown	gnl|CDD|131209
NZ_AP012978.1|WP_081999944.1|2280485_2281175_-|phosphate-signaling-complex-protein-PhoU	unknown	unknown	gnl|CDD|273990
NZ_AP012978.1|WP_052199542.1|2284789_2285824_-|PstS-family-phosphate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270372
NZ_AP012978.1|WP_043108720.1|2293007_2293322_-|co-chaperone-GroES	unknown	unknown	gnl|CDD|178988
NZ_AP012978.1|WP_043109753.1|2289497_2289971_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl|CDD|176643
NZ_AP012978.1|WP_043108726.1|2295567_2296371_-|MOSC-domain-containing-protein	unknown	unknown	gnl|CDD|225758
NZ_AP012978.1|WP_043108716.1|2288819_2289242_+|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|181730
NZ_AP012978.1|WP_081999945.1|2281185_2282061_-|phosphate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|237645
NZ_AP012978.1|WP_052199540.1|2276249_2277353_+|glycosyltransferase	unknown	unknown	gnl|CDD|340825
NZ_AP012978.1|WP_043108712.1|2283361_2284744_-|phosphate-ABC-transporter-permease-subunit-PstC	unknown	unknown	gnl|CDD|223646
NZ_AP012978.1|WP_082000012.1|2277366_2278455_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_043108719.1|2291376_2293011_-|chaperonin-GroEL	gnl|CDD|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_AP012978.1|WP_043108717.1|2290163_2291282_+|PQQ-dependent-sugar-dehydrogenase	gnl|CDD|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	0
NZ_AP012978.1|WP_043108725.1|2295025_2295571_-|DUF1415-domain-containing-protein	gnl|CDD|377792	pfam07209, DUF1415, Protein of unknown function (DUF1415). This family consists of several hypothetical bacterial proteins of around 180 residues in length. The function of this family is unknown.	5.59962e-83
NZ_AP012978.1|WP_043108715.1|2288229_2288820_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.0048e-15
NZ_AP012978.1|WP_052199541.1|2278538_2279819_-|phosphate-regulon-sensor-histidine-kinase-PhoR	gnl|CDD|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	8.69486e-140
NZ_AP012978.1|WP_043108710.1|2282073_2283369_-|phosphate-ABC-transporter-permease-PstA	gnl|CDD|223654	COG0581, PstA, ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism].	1.51547e-88
NZ_AP012978.1|WP_043108714.1|2285920_2287873_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|236729	PRK10636, PRK10636, putative ABC transporter ATP-binding protein; Provisional.	0
NZ_AP012978.1|WP_043108708.1|2279811_2280489_-|response-regulator	gnl|CDD|131209	TIGR02154, PhoB, phosphate regulon transcriptional regulatory protein PhoB. PhoB is a DNA-binding response regulator protein acting with PhoR in a 2-component system responding to phosphate ion. PhoB acts as a positive regulator of gene expression for phosphate-related genes such as phoA, phoS, phoE and ugpAB as well as itself. It is often found proximal to genes for the high-affinity phosphate ABC transporter (pstSCAB; GenProp0190) and presumably regulates these as well. [Regulatory functions, DNA interactions, Signal transduction, Two-component systems].	7.44667e-99
NZ_AP012978.1|WP_081999944.1|2280485_2281175_-|phosphate-signaling-complex-protein-PhoU	gnl|CDD|273990	TIGR02135, Uncharacterized_protein, phosphate transport system regulatory protein PhoU. This model describes PhoU, a regulatory protein of unknown mechanism for high-affinity phosphate ABC transporter systems. The protein consists of two copies of the domain described by pfam01895. Deletion of PhoU activates constitutive expression of the phosphate ABC transporter and allows phosphate transport, but causes a growth defect and so likely has some second function. [Regulatory functions, Other, Transport and binding proteins, Anions].	6.97919e-39
NZ_AP012978.1|WP_052199542.1|2284789_2285824_-|PstS-family-phosphate-ABC-transporter-substrate-binding-protein	gnl|CDD|270372	cd13654, PBP2_phosphate_like_2, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.39069e-100
NZ_AP012978.1|WP_043108720.1|2293007_2293322_-|co-chaperone-GroES	gnl|CDD|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	2.13691e-55
NZ_AP012978.1|WP_043109753.1|2289497_2289971_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl|CDD|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	2.54253e-70
NZ_AP012978.1|WP_043108726.1|2295567_2296371_-|MOSC-domain-containing-protein	gnl|CDD|225758	COG3217, COG3217, Uncharacterized Fe-S protein [General function prediction only].	1.20842e-76
NZ_AP012978.1|WP_043108716.1|2288819_2289242_+|aminoacyl-tRNA-hydrolase	gnl|CDD|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	6.30096e-67
NZ_AP012978.1|WP_081999945.1|2281185_2282061_-|phosphate-ABC-transporter-ATP-binding-protein	gnl|CDD|237645	PRK14235, PRK14235, phosphate transporter ATP-binding protein; Provisional.	0
NZ_AP012978.1|WP_052199540.1|2276249_2277353_+|glycosyltransferase	gnl|CDD|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	1.58451e-20
NZ_AP012978.1|WP_043108712.1|2283361_2284744_-|phosphate-ABC-transporter-permease-subunit-PstC	gnl|CDD|223646	COG0573, PstC, ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism].	1.2445e-87
NZ_AP012978.1|WP_082000012.1|2277366_2278455_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	4.29062e-44

Protein sequences

>NZ_AP012978.1|WP_043108714.1|2285920_2287873_+|ATP-binding-cassette-domain-containing-protein
MLHFDHLTLRRGPRLLFEDATFQIHPGQKVGLTGANGTGKSSLFALILGELQEDNGHHSLPADWTITHLAQEIPASTQPAIDYVLDGDGELRRLQGALVEAEQRGDGERIAHLHAELEHIGGYQAEARAAQLMAGLGFAPGDERRPLADFSGGWRMRLNLARTLMCRSELLLLDEPTNHLDLDAVIWLESWLKSYRGTLLLISHDREFLDSVCDHILHIEHQHAILYRGNYSAFERLRAPSSAFERLRAERLAGQQAAYEKQQREIAHMRAFVDRFRAKASKARQAQSRLKALERMQQIAPAHVDSPFHFTFRPPRRLPHPLLHLEKCSAGYNGRAIVEHASLVLAPGDRLGLLGPNGAGKSTLIKLLAGELTPLEGEREVAQDLAIGYFAQHQLEQLHPEHSPVEHLLQQDPSLGEQDARDYLGGFGFVGDQALAPVGPFSGGEKSRLVLALLVQQRPNLLLLDEPTNHLDLEMRQALATALQDFEGAMVIVSHDRHLLRTACDRLALVNGGRLTPFDGDLDDYAAWLSDHRRSAGNPAAQAASSTPKRETAEDRKARKRAEAERRARLQPLKKRLARCEQALEDLQDQRRALEEQLAAPDLYEAENKNRLTELLKQKAELDQQIEDAELEWLRAADAVETAETEETSQ
>NZ_AP012978.1|WP_052199542.1|2284789_2285824_-|PstS-family-phosphate-ABC-transporter-substrate-binding-protein
MKRMLFGSALALVLGAQTQAASRDTIHIVGSSTVYPFATVVAEHFGRATRFKTPRIESTGSGGGMKLFCAGVGVNHPDITNASRRIKKSEFAKCQANGVKEIVEIKIGYDGIAIANSRKAPRFDLSRKDLFLALARQVPDPAAPESVPNPYRTWKQVNPSLPDVGIEVLGPPPTSGTRDAFAELAMEGGCKQFAWIKALKHQDKKRYKAICHAIREDGPYIEAGENDNLIVKKLVANPRALGIFGYSYLEQNADQLQGSLVDGVAPEFELIADGSYPVSRPLFFYVKKAHVGRIPSIREYLAEFTSEKAWGDDGYLVDKGLIPMPEDERSAFAKAARELTPLEL
>NZ_AP012978.1|WP_043108712.1|2283361_2284744_-|phosphate-ABC-transporter-permease-subunit-PstC
MSLSMLFLLLVAYALAAYWLGRRVVLGRVDGDARRLHSLPRYHGYRVALLAGLPPLVLLVLWLAFDQAVIGHLVMQSLPESMRTLSEAERSLLLNDIRNLATGNIASGVPDPALTAAVERYRSLSGWSNMALPVLLLLVGLGGLGWGLLRVHPGLRARTSVERVVHVLLLASASIAILTTLGIVLSVLFEALRFFETVPLGDFLFGLEWSPQIAIRVDQVGASGAFGMVPLFAGTLMIAGIALAVAVPVGLFSAIWLAEFAGARARAWIKPLLEILAGIPTVVYGFFAALVVAPLVRGLGESLGLAVSSESALAAGLVMGVMIIPFVSPLSDDVITAVPQSLRDGSLALGATPAETVLRVVVPAALPGIVGGVLLAASRAIGETMIVVMAAGVGARLTANPLDSVTTITVQIVTLLVGDQEFDSPKTLAAFALGLVLFLATLLLNVLALYVVRRYREAYE
>NZ_AP012978.1|WP_043108710.1|2282073_2283369_-|phosphate-ABC-transporter-permease-PstA
MSKKKNKPLVKRRAIREAVLQGLARRRRRDRLLRLAGIGAIVLGLSFLAVMLVSLVSLGQSAFWQTHIRLELRLDPERLDPQGNGSLDSLSAGDYAGVIKQALRARFPEARKRREKRELYRLVSSGAAWALRDQVVADPELLGQWRAFWLLADDEVDQWFKHGEAGGVRLSERQRHWLESLRAEGAIDTFFNWTFFRNGDSREPELAGIRGALAGSFYALLVTLALSLPLGVAAAIYLEELAPRNRWTDFIEVNINNLAAVPSIVFGLLGLAVFLNFLDLPRSASLVGGLVLTLMTLPTIIITGRAALKAVLPSIREAALGIGASRMQTVFHHVLPQALPGMLTGTIIGMAQALGETAPLLMIGMVAFIVDVPQGITDPATVLPVQIYLWADSPERAFMERTAAAILVLLLFLVLMNLVAILLRRRFEKRW
>NZ_AP012978.1|WP_081999945.1|2281185_2282061_-|phosphate-ABC-transporter-ATP-binding-protein
MAIADRRALFQSVVEAALAAGDAAQPEVVESTLGTPFLERKVSLRARNVNVFYGEKQAIKDVSIDIGKHQVTAFIGPSGCGKSTFLRCFNRMNDTIEGCRVEGEIHLDDEDIHAPEMDVVPLRARVDMVFQKPNPFPKSIYENIAYGPRLHGLAASRADLDELVENSLRRAGLWDEVKDRLDAPGTGLSGGQQQRLCIARAIAIHPEVILMDEPCSALDPIATARVEELIDELRERYTIIIVTHSMQQAARVSQRTAYFHMGRLVEVDKTERIFTNPAHKLTEAYITGRFG
>NZ_AP012978.1|WP_081999944.1|2280485_2281175_-|phosphate-signaling-complex-protein-PhoU
MNGTVSNGHILRGFDKDMRKLRKRVLKMAGLVRGQMERLQLALGHDSTEQARQVIEGDRPIDLQEVKVDSFIVSLLARRAPVGRDLRYVVATSRIVTELERLGDEMTQIARVLCQESLPESGCDGHSPRSEVQHLMGHLIMLLDTALRAYEEDDARQSEVIVAGELPEQIDLRNRLKYLVECVFDNRQDVAEAVNFMLVLKSLDRGKRHIDNIAEHVIYLVTGEDIRHQ
>NZ_AP012978.1|WP_043108708.1|2279811_2280489_-|response-regulator
MTTILFVEDEAPIRDMVRFALSRAGMEMLEAGSVAEAEHLLAVRRPDLVLLDWMLPERSGIALLRHIRQHEGLSDIPVILLTALAEEAQRVQGLEAGADDYVVKPFSPPELIARIRAVLRRDLDGRLRLGELVLDPATRQVECEGSPVPLGPTEFRLLRFLLQNPNRVYSRGQLLDRVWGDDVALEERTVDVSVRRLRKALAPFGLDGCIETVRGAGYRLVSAGA
>NZ_AP012978.1|WP_052199541.1|2278538_2279819_-|phosphate-regulon-sensor-histidine-kinase-PhoR
MHEQFRAELLRLLAVAALVGLFGWASQAWALALLVGLGGLVLWQLYQVWLLEEWLVGGGGEDLRGVWRSVAEHIERVRLRARQRKKRLSRLLHRFHDTLETMPDAAVILDQRLRVQWFNSAARELLGLDAGEPVVGRPLPELLDDPALADWLRQGADASPLERRIGAAGERELELRVAPFAKDQLLLTAHDVTELKRVQTVRRDFIANVSHELRTPLTVVVGYLEMLAEEDLPGEVHDALAASLRQAERMQQLVADLLMLSRLELEDDRPPREPVDVPALLEHLVEDARRLNGDQHPVTLHLQSRAGLLGSESELASAFGNLLFNAILHTPPGTPVDLYWEVDDDGARFCVLDQGPGIPPEHLDRLTERFYRVDKSRSRERGGTGLGLSIVRHVLLRHDAVIEIESQVGEGSRFCCIFPNVRIVPA
>NZ_AP012978.1|WP_082000012.1|2277366_2278455_-|glycosyltransferase-family-4-protein
MERLNWHVADELARHGTVTVVAPEGSAARAPTGVVVHEVPGRPLWRFLLGALVSGIRQARGLRPDVVLAGSGLTAPLAWMTARLSGARAAVYVHGLDVVARHWLYRLLWIPFLRRMDRVIANSRATAALAEAAGVAPMRIEIIPPGVTLPEAITAEERETARRTFRQCHDLGDGPLLLSVGRLTTRKGMLEFVRDVFPEIVRQVPEAQLAIIGGEPAQALYAGVQSVEQIRSVAEKAGVAGKVRFLGEFTEWERLREAYLAADVHVFPVRSIPGDPEGFGMVAVEAAAHGLPTVAYATGGVVDAVADGVSGWLVPPGDTDAFAAAVVDNLEAPLSLLAMHAHAEQFARPNFGERLARALQGS
>NZ_AP012978.1|WP_052199540.1|2276249_2277353_+|glycosyltransferase
MRILFLSKRRYMSKDVIDDRYGRLYELPANLARQGHSVLGLCTAYRRLGDRRIHHHGEQGDLNWQPFDLLPHGASYAWRLPALGRTFAPDLVFSASDALQVVLGNHLARRLDVPHAVDLYDNFESFGLTRLPGLRRAFRRALQRASAISCVSEPLQKKLACELPEVPLLTLESTIDPDAHRPFDRGKAREHLGLPADAWLMGTAGALHHNRDIGLLYAAFERLATRHPDLHLALAGPVDPACPLPQHPRVHYLNQLPHAQVPLFHSALDLALICMCDSEFGRYAFPQKTYEILACGTPLLAASVDAPRSLLADWPRCLYRPGDLDQLITRIEEQRQQPCTPSLAIPSWADQAKRLESFWREHLELPE
>NZ_AP012978.1|WP_043108715.1|2288229_2288820_+|class-I-SAM-dependent-methyltransferase
MWDQRYSDDDYFYGTAPNDFLATNAGRIPNGPVLCLAEGEGRNAVHLAGLGYQVTAVDSSAAGLRKAERLARERGVTLECVHADLADYDLGTARWAGIVSIFAHLPPPLRRQVHAAIPRALRPGGILLLEAYTPAQLDHGTGGPPVAELMMDAASLRDELPGLVFDHLAECEREVVEGKGHRGTGAVVQAIARKPT
>NZ_AP012978.1|WP_043108716.1|2288819_2289242_+|aminoacyl-tRNA-hydrolase
MPLRISQKVVIPDEEIALSGIRAQGAGGQNVNKVSSAIHLRFDIRRSSLPDFYKQRLLALHDTRISKDGVVTIKAQRFRTQERNREDALERLAELIRRVGRVQKQRIPTRPTRAAKERRITEKKRRSQHKRLRGKVRTFD
>NZ_AP012978.1|WP_043109753.1|2289497_2289971_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MAFEISSSAFPRGGSIPARYTCDGDDISPPLAWNDVPEGTRSLALIVDDPDAPDPAAPKMTWVHWVLYNLPADSTGLPEGLAPADLPSGTKEGINDWKRTGYGGPCPPIGRHRYFFKLYALKVVLPFTDPLTKAELLEAMEGQVLDEAVLMGTYQRP
>NZ_AP012978.1|WP_043108717.1|2290163_2291282_+|PQQ-dependent-sugar-dehydrogenase
MSLRYFALLSCLLLRPTGTAAAPVDTELHRVDWQVVVSGLDHPWSLAFLPDGRLLITERVGRLRLVEADGRLHPKPIAGLPPIHPYGQGGLLDVALPPDFARSRRVYFSFAERGPRGHGTAVAFGVLRGHRLENVRVIFRQRPKTAETRHFGSRLVFDRQGHLFITLGDRGNRSSAQDLRRHAGSLIRIDDGGIPPDNPLVGRSDAQPEIWSYGHRNMQGAALHPLTGKLWIHEHGPQGGDELNIPEAGKNYGWPVITYGREYFTDLPIGEGTRKPGMAQPIHYWERSIAPSGMTFYTGDRFPRWRGDLFIGSLKFRLLVRLHLDDDRVVHEERMLADRLGRIRDVRQGPDGLIYLLTDADDGKLVRLLPAQ
>NZ_AP012978.1|WP_043108719.1|2291376_2293011_-|chaperonin-GroEL
MSAKIVKFHEDARERMLAGVNTLADAVKVTLGPKGRNVVLEKSFGAPRITKDGVSVAKEIELKDKFENMGAQMLKEVASKTADVAGDGTTTATVLAQAMIREGHKAIAAGMNPMDLKRGIDAAVKAAVEELKSIAKPCDDSNSIRQVATVSANWNSDVGEILAEAMEKVGRDGVITVEEGKSLENELEVVEGMQFDRGYLSPYFVNNQEKMHVELEKPYILLHDKKISNIRDLLPVLEEAAKAGRPLLIIAEDVEGEALATLVVNNLRGTLKAAAVKAPGFGDRRKAMLQDIAILTGGTVISEEVGLSLEKAKLHDLGEAARVVITKETTTIVDGAGKKDEIEARVEQIRAQIEETTSDYDREKLQERVAKLAGGVAVVKVGAATEVEMKEKKDLVDDALHATRAAVEEGIVLGGGVTLVRIASTLRDKGVDTANTDQETGVQIALRAMEEPLRQIVANAGGEASVAVQAVREKEGAWGYNAQTEEYGDMLEMGIIDPAKVTRSALQNAASIAGLMRTTEAMVAEEPKKEAAAAPGGMDAGMDF
>NZ_AP012978.1|WP_043108720.1|2293007_2293322_-|co-chaperone-GroES
MNIRPLHDRVVVRRIDAENKTAGGIIIPDNAQEKPIQGEVIAVGDGAILEDGSRRPLDLKVGDRVLFGKYSGTEVKLGDEELLVMRESDIMAVIEDADKEVKAA
>NZ_AP012978.1|WP_043108722.1|2293530_2294127_+|hypothetical-protein
MTDETRIRTETSLPEYFRRRLHRHAERLRPPPHEDTLWYLGELLHRFRRSEHFFEIHEGRLAQRPLALLYGEAQAATSQRERCLLLQRLGDLALFLGAFFPDRYARWGIRREYFIGMGSAAYDYLADSAASHRHIYRELTASFVRMLELLAAAGSRRRNTDHEEILRLYAHWMATGDPRAEQQLRALGIALSDTDGAH
>NZ_AP012978.1|WP_043108724.1|2294160_2294901_-|TSUP-family-transporter
MDFSVGQWAAIVLIFLWSGFVRTGIGFGGAALGLPLLLLVEDEPLLWLPIIGLHLLFFTSITAGGRLHHIDWGFVRWSMGWMIVPKLAGVIGLLSLPTEWMVIFVFAISAAYAVSWIVQRQVALDAPWFDRLLLVLGGYVSGASLVGAPLIAAVAIRRVPMTRYRDTLFVLWFLLVCIKMTAFLAVGVELHAGWAALLLLPAGVGHLLGLRAHQHLVHGDARRTRRVLGVGLSLGRMFVARMPFLP
>NZ_AP012978.1|WP_043108725.1|2295025_2295571_-|DUF1415-domain-containing-protein
MSDAEEQLRRWVERLVIGERLCPFASAPWATGRVRIAVCEAADDDGIYRAFLEEVERLLATDPAELETTLLAVPDALGDFADYLDMLAVLEQALAEAGLEGVLQIASFHPDYRFADEAADDHSHWTNRAPVPVFHLLREDSIGRAVASLEDPDAIPRRNRERMRELGIARLRALRDGREPG
>NZ_AP012978.1|WP_043108726.1|2295567_2296371_-|MOSC-domain-containing-protein
MSEIFSLSGLWRYPVKSLRGQGCERLAIGPRGPVHDREWMLVDESGRFLTQRQQPRMAQIGVALEDDALVFDAPGRPPLRVARAGTRERLSVQVWNDRLEAQGMDPAADAWLSDFLGQPCRLVHFPEDARRPVDPRYAQADDQVGFADGFPLLLISQAALDALNQRLDEPVDMRRFRPNLVVSGCAPHAEDGWRRIRIGGLTFRVVKPCSRCPIPGLDPETGEKRGRVLETLMQYRRGEDNRIYFGQNLLHDGSGELAVGMPVEVLE

Crispr_ID: NZ_AP012978_12

• CRISPR_ID: NZ_AP012978_12
• CRISPR_location: 2452617-2452718
• CRISPR_type: TypeI
• Repeat_type: I-C
• Spacer_info: 1 spacers
• Cas_protein_info: cas2,cas1,cas4,cas7,cas8c,WYL

Consensus repeat of NZ_AP012978_12

Consensus_repeat	Method
GCGGTCGCCCCCATCACGGGGGCGTGGATTGAAAC	CRISPRCasFinder

spacers of NZ_AP012978_12

>12.1|2452652|32|NZ_AP012978|CRISPRCasFinder
TTCAGGTTTGCTCCAAGTCGATGCCGAGGTCG

CRISPR arrays and Neighbor proteins around NZ_AP012978_12

CRISPR arrays

The CRISPR arrays of NZ_AP012978_12

>merge|NZ_AP012978|12|2452617-2452718|CRISPRCasFinder
GCGGTCGCCCCCATCACGGGGGCGTGGATTGAAACTTCAGGTTTGCTCCAAGTCGATGCCGAGGTCGGCGGTCGCCCCCATCACGGGGGCGTGGATTGAAAC

>NZ_AP012978|12|11|2452617-2452718|CRISPRCasFinder
GCGGTCGCCCCCATCACGGGGGCGTGGATTGAAAC	TTCAGGTTTGCTCCAAGTCGATGCCGAGGTCG
GCGGTCGCCCCCATCACGGGGGCGTGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP012978.1|WP_043108867.1|2441990_2442620_+|nicotinate-nucleotide-adenylyltransferase	unknown	unknown	gnl|CDD|234611
NZ_AP012978.1|WP_043108870.1|2443032_2444007_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_AP012978.1|WP_043108868.1|2442653_2443013_+|ribosome-silencing-factor	unknown	unknown	gnl|CDD|272901
NZ_AP012978.1|WP_043108873.1|2449334_2450417_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl|CDD|377458
NZ_AP012978.1|WP_043108877.1|2454378_2455170_+|putative-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|378264
NZ_AP012978.1|WP_043108875.1|2452144_2452435_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_AP012978.1|WP_043108874.1|2451101_2452133_+|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl|CDD|188360
NZ_AP012978.1|WP_043108882.1|2457625_2459074_+|ribonuclease-G	unknown	unknown	gnl|CDD|183285
NZ_AP012978.1|WP_043108876.1|2452895_2453165_+|membrane-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043108883.1|2459089_2463019_+|TIGR02099-family-protein	unknown	unknown	gnl|CDD|273971
NZ_AP012978.1|WP_052199568.1|2453512_2454379_+|DUF692-domain-containing-protein	unknown	unknown	gnl|CDD|377459
NZ_AP012978.1|WP_043109806.1|2450466_2451105_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
NZ_AP012978.1|WP_043108884.1|2463169_2464021_+|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl|CDD|143596
NZ_AP012978.1|WP_043108866.1|2440699_2441980_+|glutamate-5-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|234685
NZ_AP012978.1|WP_043108880.1|2456133_2456604_+|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH	unknown	unknown	gnl|CDD|234634
NZ_AP012978.1|WP_082000013.1|2448663_2449338_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl|CDD|378245
NZ_AP012978.1|WP_043108865.1|2440101_2440656_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP012978.1|WP_043108879.1|2455204_2456137_+|cation-transporter	unknown	unknown	gnl|CDD|223131
NZ_AP012978.1|WP_043108881.1|2456603_2457164_+|septum-formation-inhibitor-Maf	unknown	unknown	gnl|CDD|234584
NZ_AP012978.1|WP_052199567.1|2453194_2453461_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_AP012978.1|WP_043108870.1|2443032_2444007_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	1.1e-53	177.5	7.9
NZ_AP012978.1|WP_043109806.1|2450466_2451105_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	1.4e-32	108.0	0.0
NZ_AP012978.1|WP_043108873.1|2449334_2450417_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	1.9e-119	392.7	0.5
NZ_AP012978.1|WP_043108875.1|2452144_2452435_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1e-28	94.1	0.0
NZ_AP012978.1|WP_043108874.1|2451101_2452133_+|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	3.1e-149	491.4	0.4
NZ_AP012978.1|WP_082000013.1|2448663_2449338_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	5.7e-70	231.1	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP012978.1|WP_043108867.1|2441990_2442620_+|nicotinate-nucleotide-adenylyltransferase	gnl|CDD|234611	PRK00071, nadD, nicotinate-nucleotide adenylyltransferase.	3.03909e-76
NZ_AP012978.1|WP_043108870.1|2443032_2444007_+|WYL-domain-containing-protein	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.02076e-41
NZ_AP012978.1|WP_043108868.1|2442653_2443013_+|ribosome-silencing-factor	gnl|CDD|272901	TIGR00090, rsfS_iojap_ybeB, ribosome silencing factor RsfS/YbeB/iojap. This model describes a widely distributed family of bacterial proteins related to iojap from plants. It includes RsfS(YbeB) from E. coli. The gene iojap is a pattern-striping gene in maize, reflecting a chloroplast development defect in some cells. The conserved function of this protein is to silence ribosomes by binding the ribosomal large subunit and impairing joining with the small subunit in response to nutrient stress. Note that RsfS (starvation) is an author-endorsed change from the published symbol RsfA, which conflicted with previously published gene symbols. [Protein synthesis, Translation factors].	6.23532e-47
NZ_AP012978.1|WP_043108873.1|2449334_2450417_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	5.1714e-86
NZ_AP012978.1|WP_043108877.1|2454378_2455170_+|putative-DNA-binding-domain-containing-protein	gnl|CDD|378264	pfam09836, DUF2063, Putative DNA-binding domain. This family represents the N-terminal part of a Neisseria protein, UniProtKB:Q5F5I0, Structure 3dee. It runs from residues 31-117 as a helical bundle with 4 main helices. \From genomic context and the fold of the C-terminal part, it is suggested that this protein is involved in transcriptional regulation.	2.58923e-18
NZ_AP012978.1|WP_043108875.1|2452144_2452435_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.32848e-34
NZ_AP012978.1|WP_043108874.1|2451101_2452133_+|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl|CDD|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	5.71074e-178
NZ_AP012978.1|WP_043108882.1|2457625_2459074_+|ribonuclease-G	gnl|CDD|183285	PRK11712, PRK11712, ribonuclease G; Provisional.	0
NZ_AP012978.1|WP_043108879.1|2455204_2456137_+|cation-transporter	gnl|CDD|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	6.98232e-49
NZ_AP012978.1|WP_052199568.1|2453512_2454379_+|DUF692-domain-containing-protein	gnl|CDD|377459	pfam05114, DUF692, Protein of unknown function (DUF692). This family consists of several uncharacterized bacterial proteins.	4.97894e-158
NZ_AP012978.1|WP_043109806.1|2450466_2451105_+|CRISPR-associated-protein-Cas4	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	5.17029e-30
NZ_AP012978.1|WP_043108884.1|2463169_2464021_+|carbon-nitrogen-hydrolase-family-protein	gnl|CDD|143596	cd07572, nit, Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases). This subgroup includes mammalian Nit1 and Nit2, the Nit1-like domain of the invertebrate NitFhit, and various uncharacterized bacterial and archaeal Nit-like proteins. Nit1 and Nit2 are candidate tumor suppressor proteins. In NitFhit, the Nit1-like domain is encoded as a fusion protein with the non-homologous tumor suppressor, fragile histidine triad (Fhit). Mammalian Nit1 and Fhit may affect distinct signal pathways, and both may participate in DNA damage-induced apoptosis. Nit1 is a negative regulator in T cells. Overexpression of Nit2 in HeLa cells leads to a suppression of cell growth through cell cycle arrest in G2. These Nit proteins and the Nit1-like domain of NitFhit belong to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), this subgroup corresponds to class 10.	1.97451e-143
NZ_AP012978.1|WP_043108866.1|2440699_2441980_+|glutamate-5-semialdehyde-dehydrogenase	gnl|CDD|234685	PRK00197, proA, gamma-glutamyl phosphate reductase; Provisional.	0
NZ_AP012978.1|WP_043108880.1|2456133_2456604_+|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH	gnl|CDD|234634	PRK00103, PRK00103, rRNA large subunit methyltransferase; Provisional.	2.81152e-84
NZ_AP012978.1|WP_082000013.1|2448663_2449338_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	8.15162e-87
NZ_AP012978.1|WP_043108883.1|2459089_2463019_+|TIGR02099-family-protein	gnl|CDD|273971	TIGR02099, probable_transmembrane_protein, TIGR02099 family protein. This model describes a family of long proteins, over 1250 amino acids in length and present in the Proteobacteria. The degree of sequence similarity is low between sequences from different genera. Apparent membrane-spanning regions at the N-terminus and C-terminus suggest the protein is inserted into (or exported through) the membrane. [Hypothetical proteins, Conserved].	0
NZ_AP012978.1|WP_043108881.1|2456603_2457164_+|septum-formation-inhibitor-Maf	gnl|CDD|234584	PRK00032, PRK00032, septum formation inhibitor Maf.	5.14179e-95

Protein sequences

>NZ_AP012978.1|WP_043108875.1|2452144_2452435_+|CRISPR-associated-endonuclease-Cas2
MMVLITYDVNTESPGGARRLRRIAKACQDYGQRVQFSVFECLVEPAQWTQLKQTLIEEMDPERDSLRFYYLGTNWRRRVEHVGAKPAYDPEGTLIL
>NZ_AP012978.1|WP_043108874.1|2451101_2452133_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKRLLNTLYLTTQGAWLSRERETLVVKVDHEIRLRLPIHHIDSIVALGQVNATAPLLGFCAARGVRMAFFTEQGRFLARVEGPVSGNVLLRKAQYQWHESTEQSARIAGTLIAAKIVNSRTVLQRHLRDRPDCPYRADIEQAIQHLVTLLRRVRTETDLDTLRGYEGAAARAYFDCFDHLILHDDPGFRFAGRNRRPPTDPVNALLSFVYTLLRHDVASALEGVGLDPAIGFLHRARPGRPALALDLMEELRPQLADRLVLSLINRRQLRASGFNTTETGEVRMTEATRRQVLTAWQERKRETLKHPYLEETVEIGLIPYLQARLLASYLRNDLNAYPAFVWC
>NZ_AP012978.1|WP_043109806.1|2450466_2451105_+|CRISPR-associated-protein-Cas4
MEEERLIPISALQHLAYCPRQFALIHLEQAWEENRFTAEGRLLHRVVDAGASETRHDLHIARGVHLICHALGLVGKADVVEFHRAESGCTLPDREGFWRPCPVEYKRGRSKQADWDRIQLCAQALALEEQFDLAIEEGALFYGKQRRHERVTFDNRLREQTCQLARQAHALLKEATLPPPEPGTKCMHCSLEAICLPERKDAQAYLDRVLTP
>NZ_AP012978.1|WP_043108873.1|2449334_2450417_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSLENRYDFVLLFDVKEGNPNGDPDAGNLPRVDAETGQGLVTDVSLKRKVRNYVGLVKEEQPPYEIYVKEKAVLNLTHVRAYKGVEAEDQLEQDKKGHWKSKGKGSNEDAKKWLCNNFYDIRTFGAVMSLGVNCGQVRGPVQLTFARSIDPIFSQEHSITRMAVATEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEKQDGDNRTMGRKHTVPYGLYRAHGFVSAPLACQTGFSEEDLKLLWEALCNMFEHDHSAARGEMATRGLYVFKHNSKLGNAHAHDLFDRIQVGRKEDVAVPHQFSDYVVSIDDSNLPEGVELIQMS
>NZ_AP012978.1|WP_082000013.1|2448663_2449338_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLALMIKHHANRPFPDLRGISLARIHRLYPLKKWSLRNIRGGSLAGQPYPRTLLAAAVQRIRAEREVTYPRAALIKGCINRATRYSNPDRKEELTVSLDPDNTNPGYRLGRLFAVLEKIQEEANPGINATIRDRYYGSASSTPVAVFPTLIKLSKHHLGKLEHKGREVQFERLLGEIIDGIGDFPAHLSLEDQGRFAIGYYHQRQDSFKKRNAESQTENQGEDQ
>NZ_AP012978.1|WP_043108870.1|2443032_2444007_+|WYL-domain-containing-protein
MDRFDRIYQLHHLLDAARRPRPLRRLAEDMECSERTVKRTISYLRLYLHAPIEYDRAHNGYYYDTRSGEFELPGLWFNASELQALLLMQQQLEQVEPGLLEPQLAPLRSRIDELLARQHLAGNELNRRIRLIATATRDPGHRLTHIAEALLARQRLRIRYHDRSRDHSTEREISPQRLTRYRDNWYLEAWCHLRKALRLFAIERIEQLEPVDSPANEISPERLDATFDAGYGIFAGPARHTAVLAFSPQRARWVEQERWHPEQQTRWREDGRFELRLPYSNPTELIMDILRHGPHVEVLAPDSLRQAVHQQLSEALSLYDRDTE
>NZ_AP012978.1|WP_043108868.1|2442653_2443013_+|ribosome-silencing-factor
MQVEALRDLVVATLEDMKAHDIVVIDVRGRTVIADYLVIASGNSDRHVKSAAEAVAFRAKQAGEPPLGEEGVQEGEWALIDLNGVIVHVMQPRVRDYYQLEKLWELDPGAAEKLMREHE
>NZ_AP012978.1|WP_043108867.1|2441990_2442620_+|nicotinate-nucleotide-adenylyltransferase
MIGILGGTFDPVHHGHLRIALDAAEVLGLREVRLLPLGQAVHREQPRATAQQRLAMLRLAVEGHPQFIVDDREIARGGPSYMVDTLASLRAEHPDTPLCLLLGGDAFAGFARWRDPERILQLAHLAVLTRPGEPLSDDPVLAALTADRLRPPEALAAYPHGGLTRIEATQLAIASSDIRARIATGRDPSFLLPDPVLGYIREQGLYRVV
>NZ_AP012978.1|WP_043108866.1|2440699_2441980_+|glutamate-5-semialdehyde-dehydrogenase
MPQTQPIDDIDAYLRDLGERARAASRVLAAADTGAKNRALEAIAGDLDAHRDALAEANRKDLEAGRAKGLDAALLDRLELTEARIDAMIEGLRQIAALPDPVGEIFDMNYRPSGIQVGRMRVPLGVVGIIYESRPNVTADAAALCLKAGNATVLRGGSEAFHSNQAIAASIARGLGAAGLPEDAVQVIATTDRAAVGAMITLPEYIDVIIPRGGKGLIERISREARVPVIKHLDGICHVYIDDEADPQKAFDVALNAKTQRYGTCNTMETLLVNATVADDILPSLAEAYREKGVELRGCPATCAILGEACVPATDADWDTEYLAPILSIRVVEDLDAAIAHINTHGSQHTDSIITENITKARRFLREVDSSSVMINASTRFADGFEYGLGAEIGISTDKFHARGPVGLEGLTSVKWVVVGDGHIRT
>NZ_AP012978.1|WP_043108865.1|2440101_2440656_+|hypothetical-protein
MKRLGLITLFLLLAGCAGQWVHIRDNGQRQISSSRYDVALPLDWVRRETPDGLIVSRDGPDLQKILLRAVPHDKAFPTIEQTSRPDMLPSDLGARFIAELRAGDSDGLPSLEIEEEGPASLDGHEAFRLRANYRNADGIRFRLLAYGTVTDKGYVELVYVAPAIYYFARNLDDFEAVRASLKLH
>NZ_AP012978.1|WP_043108876.1|2452895_2453165_+|membrane-protein
MKLSTTSAGMVLAVAAAGMLGGCSEYGTRYSSMAATEQTVHCYGVNKCKGYNDCKTASNACKGKASCKGQGFVNMSEKACTEVGGTVGS
>NZ_AP012978.1|WP_052199567.1|2453194_2453461_+|hypothetical-protein
MKISKRTAGIGLGAALAMAAAGMTGVASTAMASSSGKVHCYGVNKCKGYNDCKSASNACKGKVSCQGQGFVLMSKHACDAIGGKAKKE
>NZ_AP012978.1|WP_052199568.1|2453512_2454379_+|DUF692-domain-containing-protein
MSRPFLGFGLGLRTDHYAYIEEHRPDVDWFEILSENYMVPGGKPLAHLDRIRADYPMVMHGVSLSIGSTDPLDLDYLAQLKTLAKRVEPHWISDHLCWTRVDHTNSHDLLPLPYNETAIAHIAERIRQVQDYLGRQILIENLSSYVTYHASEMPEWEFLDEIARRADCLVLLDINNIYVSAHNHHFDPVDYLDGMSPERVMQFHLAGHCHDGLMIIDTHDHPVCDPVWTLYADALRRFGAVSTMIERDDDIPAFPELRAELAIAERIAGETLPVPALQTSQTALRGLA
>NZ_AP012978.1|WP_043108877.1|2454378_2455170_+|putative-DNA-binding-domain-containing-protein
MDGLRDLQQAFLGHLLGEGSPIAGAIESTAGASAAERLGIYATGYRLRLKEAMETDYPRLHAYLGDTLFDRLADTYIHRYRSHGTSLRGYSRHMGELLDELPPFSGLPVLGEIERIERAFNHSFDAADRPLPGPALLERIPPAAWPDMRPVLHPSVTLLPLRYNSFAIWRALADETQPPEPTEAPAIWLIWRRDLVSRYRALPAHEAEALNAIRNGEPFGAVCEHLLQHFAPEAVPREAVQLLQSWLIEQVIATLDWEATPPS
>NZ_AP012978.1|WP_043108879.1|2455204_2456137_+|cation-transporter
MAGSSTKVILAALAGNTAIAITKFAAAVFTGSSAMLSEGIHSLVDTGNQGLLLYGMRRAKRPPDARFPFGHGKEIYFWSFVVAILIFAVGAGVSIYEGIHNMLDPRPITNPLVNYIVLGLSLVFEGGAWWFALREFGKTKGKMGYIEAVQRGKDPSMFVVLFEDSAALLGLLVAMAGIATAQFTGILWFDGLASVVIGLILGATAIWLAIETKGLLIGESANREVVAGIRELVSAEPAIEAIKELLTMHMGPDFVLVTMAADFRDDLDAGTIEHTIARLDRAIKARWPEVKKVFIEAESLVPRVEHPAPA
>NZ_AP012978.1|WP_043108880.1|2456133_2456604_+|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH
MKIHLIAVGERMPRWVQEGYAEYARRLPRECTLQLVEIAPGRRGKGADTARAVREEGERLLAAIPRGARVIALEVNGRPWSTEQLAGQLEKWLAGGSDVALLVGGPEGLSEAARKAAAQQWSLSPLTLPHPLVRVIVAEQLYRAWSILANHPYHRA
>NZ_AP012978.1|WP_043108881.1|2456603_2457164_+|septum-formation-inhibitor-Maf
MLILASQSPRRAELLRQIGVDFRVAPAHIDETPQPGEPPADYVARMAREKARATAVQHPGALVLGADTSVILDGHILGKPADREEGIAMLLALGGREHQVLTAVALAGPHEDQALSASRVRFRPVGREEAARYWATGEPADKAGGYAIQGLGAVFVEHIEGSYSGIMGLPLFETAQLLADAGLPRP
>NZ_AP012978.1|WP_043108882.1|2457625_2459074_+|ribonuclease-G
MNEEILINVTPPETRVAVIENGVVQEIIIERTARRGLVGNIYKGKVCRVLPGMQAAFVDVGLERAAFLHASDIYCTSGREQPITELVREGGEIVVQVVKDPLGSKGARLTTNVSIPSRYMVFMPNMRSVGVSQKIEDEDERVRLREILARFAAESELPAGFIARTAAEGIGEEALRQDMLYLQRLWQSIKEKARNVKAVEVLHEDLPLGLRALRDLVGPEVERVRIDSRSTFEKARQFAHKFLPDADTQIEYYPGERPIFDLYGVEDEIQKALRRTVELKSGGHLVIDQTEAMTTIDVNTGAFVGHRTLEETIFKTNLEAAQAICRQLRLRNLGGIIIIDFIDMTDLDHKRQVIRALERCLARDHAKTHISEVSSLGLVEMTRKRTRESLEHVLCETCPTCRGRGSIKTAETTCYEIFREILREARQFDVEQLLVLAAPDVIDRLLDEESQNLAELEQFIGKPIKLQAEALYTQEQYDVVLV
>NZ_AP012978.1|WP_043108883.1|2459089_2463019_+|TIGR02099-family-protein
MKGLLRLTRRFLIVLILGWGLLALLVRLSTPLLEHAREPLARWLSEQAGMPVQITRLEASWWGLGPRLDLYDVRLGEGAAGIHLREVELDLNHTNLLRGNLFDALRLTIEGLQLNLVLEADGQLHVEGFPVRDGGQPAIALPRYLRLRNTRLTWEDRRYGAPPITIDPLYLDVARDGQHLHLNGGLDSSFGKLHFAADIHGYPAGRHWRGTSYLKGEALALPPLLGRYLPAPYHLLGGRLDLELWQVWENAREIAARGHVEAHRLRFGNREQPGREFSLHRASADLDFAEATDGEWRILSDALTLQTGPDDPPLTTALAIRHRPDPRGTLDIAATRLPVALLVQALHLRPTDPALDEALAALAPRGELQALRLHIAPGQADSWALDTRLRNIAAKPWQGFPGFQGLDGRLTATAERARLALDSKALPLDYRELFRAPHRLEQLSGVLHWQRETDGWRLFTDDLRLATPDLRGALWLDLQQHQGQTPRLALRARIEDGAVEATGRYLPTAIMSDELVDWLDHALQGGRMERADLLLVGPLADFPFNEHANGVFEVDARLADVDLDYRSGWPALHQVAARLFFHQNSLDIDLPEGRVYDSRLLDTHVRLATLNPASPLQVTARIEGPLADELRLLREPALRGRFGDIAKQMQAEGPTRLDLDFQLPLGAHGARLALDGRLYLRGNRLHLPKWQVALEQLKGEIAFDLHSLRARNLRGQAFGAPLRLDIEPVAEGTRIRARARWGSTLLQQRFPALPLHLASGASDFTLELDFPAQRQGKRPVLLSLRSDLKGMRLDLPAPLGKQAAQARPLAITLPLGQPPGPLHLRYDKALDARFSLDGHRGELRYARGQAQLPRKNGFRVLARVKTLDIGAWRELFASLARDGRQPPPWSVELEAKRLRVGELAIDKARLQAQHESGGIIDGRLEAPLVTGDLHYEPGERGQLHLNLEQLHIRFDPETASAPPPDPASGPDPRTLPRLVFNCADLRINQADLGVAHLALQPATDGADITELDFKGPAGTLEARGRWAWRKGRAHTYLGGRFQSKDLGAFLAGLGYPRQMIDARADIRFDLDWPGHPAQIHRAALHGQGKIDIRDGRLADVDPGIARVLGLLSLDALSRRLRLDFGDVLKKGYTFDSIVGSFQLGDGQAITRDLVVDGPSGRIEIGGRIGLVARDFDQVVQVTPKLDTTLAIAGTIAGGPVAGLATLIAQRLLSDEIDQINRFEYSVTGSWDDPKLTPLESGGPISRLFNTLGGKDTQRKTEAQEKAIDENKTRPRRNVLQKLLGTGKTPPSKQPSPAETPPADEGAFPQ
>NZ_AP012978.1|WP_043108884.1|2463169_2464021_+|carbon-nitrogen-hydrolase-family-protein
MSVTSSPLKAAAIQMASGTNVNANLLTIEKLLEEAARQGATLAVLPENFAYLGASGRDVLPYREVQGDGPLQHFLSQIAARLGIWIVGGTIPLEGEDAGRWRAASLVFDAEGREVARYDKQHLFDVTLPDSDEHYSESDAIEPGNEVVVVDSPIGRLGLAVCYDLRFPELFRAMVDRGAEVFALPAAFTAVTGRAHWEVLVRARAIENLAWVIAGAQGGFHVGGRETWGHSMVVDPWGSVLACQERGNGIAIATIDPAFQRATRRSFPCLDHRRLQCAADETE

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_AP012978_3	3.2|734566|34|NZ_AP012978|CRT	734566-734599	34	NZ_AP012978.1	735248-735281	0	1.0
NZ_AP012978_4	4.2|821064|22|NZ_AP012978|CRT	821064-821085	22	NZ_AP012978.1	840996-841017	0	1.0
NZ_AP012978_4	4.2|821064|22|NZ_AP012978|CRT	821064-821085	22	NZ_AP012978.1	1889775-1889796	0	1.0
NZ_AP012978_4	4.2|821064|22|NZ_AP012978|CRT	821064-821085	22	NZ_AP012978.1	2168255-2168276	0	1.0
NZ_AP012978_4	4.2|821064|22|NZ_AP012978|CRT	821064-821085	22	NZ_AP012978.1	1541682-1541703	0	1.0
NZ_AP012978_4	4.2|821064|22|NZ_AP012978|CRT	821064-821085	22	NZ_AP012978.1	1571607-1571628	0	1.0
NZ_AP012978_9	9.1|1571636|28|NZ_AP012978|CRISPRCasFinder	1571636-1571663	28	NZ_AP012978.1	1592192-1592219	0	1.0
NZ_AP012978_9	9.1|1571636|28|NZ_AP012978|CRISPRCasFinder	1571636-1571663	28	NZ_AP012978.1	487672-487699	0	1.0
NZ_AP012978_3	3.2|734566|34|NZ_AP012978|CRT	734566-734599	34	NZ_AP012978.1	1814018-1814051	1	0.971
NZ_AP012978_3	3.4|734684|39|NZ_AP012978|CRT	734684-734722	39	NZ_AP012978.1	903954-903992	1	0.974
NZ_AP012978_3	3.4|734684|39|NZ_AP012978|CRT	734684-734722	39	NZ_AP012978.1	1455833-1455871	1	0.974
NZ_AP012978_4	4.2|821064|22|NZ_AP012978|CRT	821064-821085	22	NZ_AP012978.1	2468401-2468422	1	0.955
NZ_AP012978_4	4.2|821064|22|NZ_AP012978|CRT	821064-821085	22	NZ_AP012978.1	228416-228437	1	0.955
NZ_AP012978_9	9.1|1571636|28|NZ_AP012978|CRISPRCasFinder	1571636-1571663	28	NZ_AP012978.1	1571689-1571716	1	0.964
NZ_AP012978_3	3.2|734566|34|NZ_AP012978|CRT	734566-734599	34	NZ_AP012978.1	308939-308972	2	0.941
NZ_AP012978_3	3.2|734566|34|NZ_AP012978|CRT	734566-734599	34	NZ_AP012978.1	1429597-1429630	2	0.941
NZ_AP012978_3	3.2|734566|34|NZ_AP012978|CRT	734566-734599	34	NZ_AP012978.1	1429651-1429684	2	0.941
NZ_AP012978_3	3.2|734566|34|NZ_AP012978|CRT	734566-734599	34	NZ_AP012978.1	1489601-1489634	2	0.941
NZ_AP012978_3	3.2|734566|34|NZ_AP012978|CRT	734566-734599	34	NZ_AP012978.1	1753525-1753558	2	0.941
NZ_AP012978_3	3.2|734566|34|NZ_AP012978|CRT	734566-734599	34	NZ_AP012978.1	1956422-1956455	2	0.941
NZ_AP012978_3	3.4|734684|39|NZ_AP012978|CRT	734684-734722	39	NZ_AP012978.1	696238-696276	2	0.949
NZ_AP012978_3	3.4|734684|39|NZ_AP012978|CRT	734684-734722	39	NZ_AP012978.1	915030-915068	2	0.949
NZ_AP012978_3	3.4|734684|39|NZ_AP012978|CRT	734684-734722	39	NZ_AP012978.1	961883-961921	2	0.949
NZ_AP012978_3	3.4|734684|39|NZ_AP012978|CRT	734684-734722	39	NZ_AP012978.1	1429705-1429743	2	0.949
NZ_AP012978_3	3.4|734684|39|NZ_AP012978|CRT	734684-734722	39	NZ_AP012978.1	1455951-1455989	2	0.949
NZ_AP012978_3	3.4|734684|39|NZ_AP012978|CRT	734684-734722	39	NZ_AP012978.1	1456010-1456048	2	0.949
NZ_AP012978_3	3.4|734684|39|NZ_AP012978|CRT	734684-734722	39	NZ_AP012978.1	1592171-1592209	2	0.949
NZ_AP012978_3	3.4|734684|39|NZ_AP012978|CRT	734684-734722	39	NZ_AP012978.1	2468371-2468409	2	0.949
NZ_AP012978_4	4.2|821064|22|NZ_AP012978|CRT	821064-821085	22	NZ_AP012978.1	2168200-2168221	2	0.909
NZ_AP012978_4	4.2|821064|22|NZ_AP012978|CRT	821064-821085	22	NZ_AP012978.1	2364061-2364082	2	0.909
NZ_AP012978_6	6.1|961846|29|NZ_AP012978|CRISPRCasFinder	961846-961874	29	NZ_AP012978.1	1492545-1492573	2	0.931
NZ_AP012978_6	6.1|961846|29|NZ_AP012978|CRISPRCasFinder	961846-961874	29	NZ_AP012978.1	1520295-1520323	2	0.931

1. spacer 3.2|734566|34|NZ_AP012978|CRT matches to position: 735248-735281, mismatch: 0, identity: 1.0

gaggacgccgctcccacatgtaggaggcccgtcc	CRISPR spacer
gaggacgccgctcccacatgtaggaggcccgtcc	Protospacer
**********************************

2. spacer 4.2|821064|22|NZ_AP012978|CRT matches to position: 840996-841017, mismatch: 0, identity: 1.0

tggttcggcccggggacgggcc	CRISPR spacer
tggttcggcccggggacgggcc	Protospacer
**********************

3. spacer 4.2|821064|22|NZ_AP012978|CRT matches to position: 1889775-1889796, mismatch: 0, identity: 1.0

tggttcggcccggggacgggcc	CRISPR spacer
tggttcggcccggggacgggcc	Protospacer
**********************

4. spacer 4.2|821064|22|NZ_AP012978|CRT matches to position: 2168255-2168276, mismatch: 0, identity: 1.0

tggttcggcccggggacgggcc	CRISPR spacer
tggttcggcccggggacgggcc	Protospacer
**********************

5. spacer 4.2|821064|22|NZ_AP012978|CRT matches to position: 1541682-1541703, mismatch: 0, identity: 1.0

tggttcggcccggggacgggcc	CRISPR spacer
tggttcggcccggggacgggcc	Protospacer
**********************

6. spacer 4.2|821064|22|NZ_AP012978|CRT matches to position: 1571607-1571628, mismatch: 0, identity: 1.0

tggttcggcccggggacgggcc	CRISPR spacer
tggttcggcccggggacgggcc	Protospacer
**********************

7. spacer 9.1|1571636|28|NZ_AP012978|CRISPRCasFinder matches to position: 1592192-1592219, mismatch: 0, identity: 1.0

cgtgggagcggcgtccccgccgcgaaca	CRISPR spacer
cgtgggagcggcgtccccgccgcgaaca	Protospacer
****************************

8. spacer 9.1|1571636|28|NZ_AP012978|CRISPRCasFinder matches to position: 487672-487699, mismatch: 0, identity: 1.0

cgtgggagcggcgtccccgccgcgaaca	CRISPR spacer
cgtgggagcggcgtccccgccgcgaaca	Protospacer
****************************

9. spacer 3.2|734566|34|NZ_AP012978|CRT matches to position: 1814018-1814051, mismatch: 1, identity: 0.971

gaggacgccgctcccacatgtaggaggcccgtcc	CRISPR spacer
gaggacaccgctcccacatgtaggaggcccgtcc	Protospacer
******.***************************

10. spacer 3.4|734684|39|NZ_AP012978|CRT matches to position: 903954-903992, mismatch: 1, identity: 0.974

ggggacgccgctcccacaggtgatgtaggaggcccgtcc	CRISPR spacer
ggggacgccgctcccacaggtggtgtaggaggcccgtcc	Protospacer
**********************.****************

11. spacer 3.4|734684|39|NZ_AP012978|CRT matches to position: 1455833-1455871, mismatch: 1, identity: 0.974

ggggacgccgctcccacaggtgatgtaggaggcccgtcc	CRISPR spacer
ggggacgccgctcccacaggtaatgtaggaggcccgtcc	Protospacer
*********************.*****************

12. spacer 4.2|821064|22|NZ_AP012978|CRT matches to position: 2468401-2468422, mismatch: 1, identity: 0.955

tggttcggcccggggacgggcc	CRISPR spacer
tggttcggcccggggacggacc	Protospacer
*******************.**

13. spacer 4.2|821064|22|NZ_AP012978|CRT matches to position: 228416-228437, mismatch: 1, identity: 0.955

tggttcggcccggggacgggcc	CRISPR spacer
tggtttggcccggggacgggcc	Protospacer
*****.****************

14. spacer 9.1|1571636|28|NZ_AP012978|CRISPRCasFinder matches to position: 1571689-1571716, mismatch: 1, identity: 0.964

cgtgggagcggcgtccccgccgcgaaca	CRISPR spacer
cgtaggagcggcgtccccgccgcgaaca	Protospacer
***.************************

15. spacer 3.2|734566|34|NZ_AP012978|CRT matches to position: 308939-308972, mismatch: 2, identity: 0.941

gaggacgccgctcccacatgtaggaggcccgtcc	CRISPR spacer
gaggacgccgctcccacaggtaggaggcctgtcc	Protospacer
****************** **********.****

16. spacer 3.2|734566|34|NZ_AP012978|CRT matches to position: 1429597-1429630, mismatch: 2, identity: 0.941

gaggacgccgctcccacatgtaggaggcccgtcc	CRISPR spacer
gaggacgccgctcccacctgtcggaggcccgtcc	Protospacer
***************** *** ************

17. spacer 3.2|734566|34|NZ_AP012978|CRT matches to position: 1429651-1429684, mismatch: 2, identity: 0.941

gaggacgccgctcccacatgtaggaggcccgtcc	CRISPR spacer
gaggacgccgctcccacctgtcggaggcccgtcc	Protospacer
***************** *** ************

18. spacer 3.2|734566|34|NZ_AP012978|CRT matches to position: 1489601-1489634, mismatch: 2, identity: 0.941

gaggacgccgctcccacatgtaggaggcccgtcc	CRISPR spacer
gaggacgccgctcccacaggcaggaggcccgtcc	Protospacer
****************** *.*************

19. spacer 3.2|734566|34|NZ_AP012978|CRT matches to position: 1753525-1753558, mismatch: 2, identity: 0.941

gaggacgccgctcccacatgtaggaggcccgtcc	CRISPR spacer
gaggacgccgctcccacctgcaggaggcccgtcc	Protospacer
***************** **.*************

20. spacer 3.2|734566|34|NZ_AP012978|CRT matches to position: 1956422-1956455, mismatch: 2, identity: 0.941

gaggacgccgctcccacatgtaggaggcccgtcc	CRISPR spacer
gaggacgccgctcccacaggtgggaggcccgtcc	Protospacer
****************** **.************

21. spacer 3.4|734684|39|NZ_AP012978|CRT matches to position: 696238-696276, mismatch: 2, identity: 0.949

ggggacgccgctcccacaggtgatgtaggaggcccgtcc	CRISPR spacer
ggggacgccgctcccacaggtggtgcaggaggcccgtcc	Protospacer
**********************.**.*************

22. spacer 3.4|734684|39|NZ_AP012978|CRT matches to position: 915030-915068, mismatch: 2, identity: 0.949

ggggacgccgctcccacaggtgatgtaggaggcccgtcc	CRISPR spacer
ggggacgccgctcccacaggtggtgcaggaggcccgtcc	Protospacer
**********************.**.*************

23. spacer 3.4|734684|39|NZ_AP012978|CRT matches to position: 961883-961921, mismatch: 2, identity: 0.949

ggggacgccgctcccacaggtgatgtaggaggcccgtcc	CRISPR spacer
ggggacgccgctcccacaggtgctgtaggaagcccgtcc	Protospacer
********************** *******.********

24. spacer 3.4|734684|39|NZ_AP012978|CRT matches to position: 1429705-1429743, mismatch: 2, identity: 0.949

ggggacgccgctcccacaggtgatgtaggaggcccgtcc	CRISPR spacer
ggagacgccgctcccacaggtggtgtaggaggcccgtcc	Protospacer
**.*******************.****************

25. spacer 3.4|734684|39|NZ_AP012978|CRT matches to position: 1455951-1455989, mismatch: 2, identity: 0.949

ggggacgccgctcccacaggtgatgtaggaggcccgtcc	CRISPR spacer
ggggacgccgctcccacaggcaatgtaggaggcccgtcc	Protospacer
********************..*****************

26. spacer 3.4|734684|39|NZ_AP012978|CRT matches to position: 1456010-1456048, mismatch: 2, identity: 0.949

ggggacgccgctcccacaggtgatgtaggaggcccgtcc	CRISPR spacer
ggggacgccgctcccacaggcaatgtaggaggcccgtcc	Protospacer
********************..*****************

27. spacer 3.4|734684|39|NZ_AP012978|CRT matches to position: 1592171-1592209, mismatch: 2, identity: 0.949

ggggacgccgctcccacaggtgatgtaggaggcccgtcc	CRISPR spacer
ggggacgccgctcccacggatgatgtaggaggcccgtcc	Protospacer
*****************.*.*******************

28. spacer 3.4|734684|39|NZ_AP012978|CRT matches to position: 2468371-2468409, mismatch: 2, identity: 0.949

ggggacgccgctcccacaggtgatgtaggaggcccgtcc	CRISPR spacer
ggggacgccgctcccacaggcgatgtaggaggtccgtcc	Protospacer
********************.***********.******

29. spacer 4.2|821064|22|NZ_AP012978|CRT matches to position: 2168200-2168221, mismatch: 2, identity: 0.909

tggttcggcccggggacgggcc	CRISPR spacer
tggttcggcctggagacgggcc	Protospacer
**********.**.********

30. spacer 4.2|821064|22|NZ_AP012978|CRT matches to position: 2364061-2364082, mismatch: 2, identity: 0.909

tggttcggcccggggacgggcc	CRISPR spacer
tgattcggcccgaggacgggcc	Protospacer
**.*********.*********

31. spacer 6.1|961846|29|NZ_AP012978|CRISPRCasFinder matches to position: 1492545-1492573, mismatch: 2, identity: 0.931

gggtaggaggcctgtccccgggccgaaca	CRISPR spacer
gggtaggaggcccgtcctcgggccgaaca	Protospacer
************.****.***********

32. spacer 6.1|961846|29|NZ_AP012978|CRISPRCasFinder matches to position: 1520295-1520323, mismatch: 2, identity: 0.931

gggtaggaggcctgtccccgggccgaaca	CRISPR spacer
gggtaggaggcccgtccccaggccgaaca	Protospacer
************.******.*********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP012978_5	5.1|878869|29|NZ_AP012978|CRISPRCasFinder	878869-878897	29	NZ_CP049249	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence	529189-529217	5	0.828
NZ_AP012978_7	7.1|1002793|30|NZ_AP012978|CRISPRCasFinder	1002793-1002822	30	NC_012853	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132503, complete sequence	419441-419470	5	0.833
NZ_AP012978_4	4.1|821005|31|NZ_AP012978|CRT	821005-821035	31	NC_015582	Novosphingobium sp. PP1Y plasmid Spl, complete sequence	5653-5683	6	0.806
NZ_AP012978_4	4.3|821114|31|NZ_AP012978|CRT	821114-821144	31	NC_015582	Novosphingobium sp. PP1Y plasmid Spl, complete sequence	5653-5683	6	0.806
NZ_AP012978_5	5.1|878869|29|NZ_AP012978|CRISPRCasFinder	878869-878897	29	NZ_CP029333	Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence	71106-71134	6	0.793
NZ_AP012978_5	5.1|878869|29|NZ_AP012978|CRISPRCasFinder	878869-878897	29	NC_022654	Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence	15563-15591	6	0.793
NZ_AP012978_5	5.1|878869|29|NZ_AP012978|CRISPRCasFinder	878869-878897	29	NZ_CP013345	Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence	48386-48414	6	0.793
NZ_AP012978_5	5.1|878869|29|NZ_AP012978|CRISPRCasFinder	878869-878897	29	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1090565-1090593	7	0.759
NZ_AP012978_5	5.1|878869|29|NZ_AP012978|CRISPRCasFinder	878869-878897	29	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	692295-692323	7	0.759
NZ_AP012978_5	5.1|878869|29|NZ_AP012978|CRISPRCasFinder	878869-878897	29	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	349551-349579	7	0.759
NZ_AP012978_5	5.1|878869|29|NZ_AP012978|CRISPRCasFinder	878869-878897	29	KT803877	Burkholderia phage PE067, complete genome	10666-10694	7	0.759
NZ_AP012978_9	9.1|1571636|28|NZ_AP012978|CRISPRCasFinder	1571636-1571663	28	NZ_CP021033	Rhizobium sp. NXC14 plasmid pRspNXC14c, complete sequence	844196-844223	7	0.75
NZ_AP012978_6	6.1|961846|29|NZ_AP012978|CRISPRCasFinder	961846-961874	29	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	98091-98119	8	0.724
NZ_AP012978_12	12.1|2452652|32|NZ_AP012978|CRISPRCasFinder	2452652-2452683	32	MN813687	Mycobacterium phage Onyinye, complete genome	34516-34547	9	0.719

1. spacer 5.1|878869|29|NZ_AP012978|CRISPRCasFinder matches to NZ_CP049249 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.828

tgtgggagcgacgtcctcgtcgcgaacgg	CRISPR spacer
tggaggagcgacgtcctcgacgcgaatgt	Protospacer
** .*************** ******.* 

2. spacer 7.1|1002793|30|NZ_AP012978|CRISPRCasFinder matches to NC_012853 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132503, complete sequence) position: , mismatch: 5, identity: 0.833

-tcctgcctgtaggaggtccgtcgccgggct	CRISPR spacer
gtcatg-ctggaggaggtccgccgccgggcg	Protospacer
 ** ** *** **********.******** 

3. spacer 4.1|821005|31|NZ_AP012978|CRT matches to NC_015582 (Novosphingobium sp. PP1Y plasmid Spl, complete sequence) position: , mismatch: 6, identity: 0.806

cattcgg--cccgaggacgggcctgttgcacca	CRISPR spacer
--tgcggtttccgaggaccgccctgttgcacca	Protospacer
  * ***  .******** * ************

4. spacer 4.3|821114|31|NZ_AP012978|CRT matches to NC_015582 (Novosphingobium sp. PP1Y plasmid Spl, complete sequence) position: , mismatch: 6, identity: 0.806

cattcgg--cccgaggacgggcctgttgcacca	CRISPR spacer
--tgcggtttccgaggaccgccctgttgcacca	Protospacer
  * ***  .******** * ************

5. spacer 5.1|878869|29|NZ_AP012978|CRISPRCasFinder matches to NZ_CP029333 (Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgggagcgacgtcctcgtcgcgaacgg	CRISPR spacer
ggaggcggcgacgtcctcgtcgcgcacgt	Protospacer
 * ** .***************** *** 

6. spacer 5.1|878869|29|NZ_AP012978|CRISPRCasFinder matches to NC_022654 (Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgggagcgacgtcctcgtcgcgaacgg	CRISPR spacer
ggaggcggcgacgtcctcgtcgcgcacgt	Protospacer
 * ** .***************** *** 

7. spacer 5.1|878869|29|NZ_AP012978|CRISPRCasFinder matches to NZ_CP013345 (Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgg-gagcgacgtcctcgtcgcgaacgg	CRISPR spacer
-gtgacgagcgacgtcctcgtcgagaattt	Protospacer
 ***. ***************** ***.  

8. spacer 5.1|878869|29|NZ_AP012978|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 7, identity: 0.759

tgtgggagcgacgtcctcgtcgcgaacgg	CRISPR spacer
gaggcgggcgacgtcctcgtcgcggacgt	Protospacer
 . * *.*****************.*** 

9. spacer 5.1|878869|29|NZ_AP012978|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 7, identity: 0.759

tgtgggagcgacgtcctcgtcgcgaacgg	CRISPR spacer
gaggcgggcgacgtcctcgtcgcggacgt	Protospacer
 . * *.*****************.*** 

10. spacer 5.1|878869|29|NZ_AP012978|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 7, identity: 0.759

tgtgggagcgacgtcctcgtcgcgaacgg	CRISPR spacer
gaggcgggcgacgtcctcgtcgcggacgt	Protospacer
 . * *.*****************.*** 

11. spacer 5.1|878869|29|NZ_AP012978|CRISPRCasFinder matches to KT803877 (Burkholderia phage PE067, complete genome) position: , mismatch: 7, identity: 0.759

tgtgggagcgacgtcctcgtcgcgaacgg	CRISPR spacer
ttctgctgcgacgtccacgtcgcgaacgc	Protospacer
* . *  ********* *********** 

12. spacer 9.1|1571636|28|NZ_AP012978|CRISPRCasFinder matches to NZ_CP021033 (Rhizobium sp. NXC14 plasmid pRspNXC14c, complete sequence) position: , mismatch: 7, identity: 0.75

cgtgggagcggcgtccccgccgcgaaca	CRISPR spacer
gctgagagcggcgtcaccgccgcgatgc	Protospacer
  **.********** *********   

13. spacer 6.1|961846|29|NZ_AP012978|CRISPRCasFinder matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 8, identity: 0.724

gggtaggaggcctgtccccgggccgaaca	CRISPR spacer
gttggaaaggcctgtctccgggccgaact	Protospacer
*   ...*********.*********** 

14. spacer 12.1|2452652|32|NZ_AP012978|CRISPRCasFinder matches to MN813687 (Mycobacterium phage Onyinye, complete genome) position: , mismatch: 9, identity: 0.719

ttcaggtttgctccaagtcgatgccgaggtcg	CRISPR spacer
agatgttttgctcgaagtcgatgcagaggatg	Protospacer
    * ******* ********** **** .*

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	828935 : 838466	7	uncultured_Caudovirales_phage(33.33%)	NA	NA
DBSCAN-SWA_2	1396488 : 1407132	10	Cronobacter_phage(16.67%)	tRNA,integrase	attL 1389590:1389605|attR 1403568:1403583

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_AP012978|828935:838466|DBSCAN-SWA
ATCAGGCGTCGATGCGCTTGTACTTGATGCGCTTCGGATTGACCGCGTCCTCGCCGAGGCGGCGCTTCTTGTCTTCCTCGTAGTCGGCGAAGTTACCCTCGAACCAGACCACTTTCGAGTCGCCCTCGAAGGCGAGGATGTGGGTGGCGATACGGTCGAGGAACCAGCGGTCGTGCGAGATCACCACCACGCAACCGGGGAAGGCGAGGATCGCCTCTTCCAGCGCGCGCAGGGTCTCCACGTCGAGATCGTTGGTCGGCTCGTCGAGCAGCAGCAGGTTGCCGCCCGACTTGAGCAGCTTGGCCAGGTGCACCCGGTTGCGCTCGCCGCCCGAGAGGTCCCCGACCTTCTTCTGCTGGTCCGAGCCGCGGAAGTTGAAGCGCGAGCAGTAGGCGCGCGACTGCACCTGGTAGTTGCCCACGGTGATGATGTCCTGGCCGTCGGAGATCTCCTCCCAGACGGTCTTGTTCGGGTCGAGCGCGTCGCGGCTCTGGTCCACCGCGGCGATCTTCACCGTGGGGCCGATGCGCAGCTCGCCGTCGTCGGGCTGTTCCGCGCCGGTCATGATGCGGAACAGGGTGGTCTTGCCCGCGCCGTTGGGGCCGATGATGCCGACGATGCCGCCCGGCGGCAGGTTGAAGCTGAGGTCCTCGTAGAGCACCTTGTCGCCGTAGGCCTTCTTCAGGTGCTTGGCCTCGATCACCAGATCGCCCAGGCGCGGCCCCGGCGGGATGTAGATCTCGTTGGTCTCGTTGCGCTTCTGGAATTCCTGGTTCTGCAGCTCGTCGAACTGCTTGAGACGTGCCTTGGACTTGGCGTGCCGCCCCTTGGGGTTGGAGCGTACCCATTCCAGTTCCTGCTTCATGGCCTTGATGCGTGCCTGCTCGGCCTTCTGTTCCTGCTCGAGGCGCTTTTCCTTCTGTTCCAGCCAGGAGGAATAGTTGCCTTCCCAGGGGATGCCGTGACCACGGTCGAGCTCGAGGATCCAGCCGGCCACGTTGTCGAGGAAATAACGGTCGTGGGTCACCGCCACCACGGTACCGGGATAGTCGTGCAGGAAGCGCTCCAGCCAGGCCACCGACTCGGCGTCGAGATGGTTGGTCGGCTCGTCGAGCAGCAGCATGTCGGGTTTGGACAGCAGCAGCCGGCACAGGGCCACGCGGCGGCGCTCGCCGCCCGACAGTTTGGTCACATCGGCATCCCAGGGGGGCAGGCGCAACGCCTCGGCGGCCACCTCGAGCTGGCGCTCCAGGTTGTGCCCGTCGGCGGCCTGGATGATGTTCTCCAGCTCGGCCTGGCGCTTGGCCAGGGCGTCGAAATCGGCGTCGGGCTCGGCGTAGGCGGCGTAGACCTTCTCCAACTCGTCCATCGCCTGCTTGACCTCGCCGAGGGCTTCCTCGACGTTGCCGCGCACGTCCTTTTCGGGGTCGAGTTGCGGCTCCTGTGGCAGGTAGCCGATCTTGATGCCGGGCTGTGGCCGGGCCTCGCCCTCGTAGTCGGTGTCCACGCCGGCCATGATGCGCAGCAGGGTGGACTTGCCCGCGCCGTTGAGGCCGAGCACGCCGATCTTGGCGCCGGGGAAGAAGGACAGGGAGATGTCGCGCAGGATCTGCCGCTTGGGCGGCACGATCTTGCTGACGCGGTTCATGGTGAAGATGTACTGGGCCATGGGTCTTCGAAAACTCGGGTTGAAAGCTTGAATCACCCTGTCAGGGTGTTGCCTGGTCAGGTTCCGGTGTGGAGCTGCGCCGCCTGCAGGGTGTTCTCCAGCAGGGTGGCCACGGTCATGGGTCCCACGCCGCCGGGCACCGGCGTGATCCAGCCGGCGACCTCCCTGGCCGCCTCGAAGTCCACGTCGCCGCACAGGGAGCCGTCGTCCAGACGGTTGATGCCCACATCGATGACGATGGCACCGGGTTTGATCCAGTCTCCCTGCACGAAGTTCGGCACGCCCACGGCGGCCACCACGATGTCGGCCTGGCGCACCTTGTCGGCCAGGTCGCGGGTGCGGCTGTGGCAGATGGTCGGGGTACAGCGCGCGGCCAGCAGTTCCAGCAGCATCGGTCGGCCGACGATGTTGGACTGGCCGAGGACGATGGCGTCCTTTCCTTCCAGCTCGACGCCGGTGTGCGCCAGCAGGGTCATCACGCCCTTGGGGGTACAGGGCCGCAGCACCGGCATGCGCAGCGCCAGCCGCCCGATGTTGTAGGGATGGAAGCCGTCCACGTCCTTGTCCGGGTGGATGCGCTCGGTGACGGCGTGTTCGTCGATCTGCACCGGCAGCGGCAGTTGTACCAGGATGCCGTCCACGTCGTCGCGCGCGTTCAGGCCGTCGATCAGCTCCAGCAGCACTTCCTGCGAAGTGTCGTTGGGGAGCTGGATCAGTTCGGACTTGAAGCCGGCCTTCTCGCAGGCCAGCTGCTTGTTGCGCACATAGACCTGGGATGCCGGGTTTTCGCCGACCAGTACCACCACCAGGCCGGGGGGACGCTGTCCCTCCGTGACGCGTTGTTCGACCTGCAGGCGCACCTGTTCACGCACGTCGGTAGCGATGGCCTTGCCATCGAGAATCTGGGCACTCATGGGACCTTGTCGTTCTGCCGGGTTGCTCGGATAGAGGCCGGAAATCATACCAGATGTGCTGTTGTTTCCGGCATGGAGACTTCGCGTCTAGAGAGGCCGCTGAAAAAGTACTCTCTTTCCCTGTCCCGCGTGTGGGGGAGCCCCGGAAGGGGAGTTCAGGCCTGTATTCGTCTCGTCCTGATCGTGTCCCCGCAAGCCAGGGAGAAACTCGGCCGGAGGCTCCCTAAAGTCCGGCAGAAAGGGGTCGTTAATCTCTGGGTAGCAGCGAGATATCCGTTCGGCGACTGGGAGTGCATGAGACCATGTTTGCTTTTGGCAGGACCCGGAAACGTCTGGAGCAGGAGCAGGCAAGGATGGCCGAATTGGAAAGCGAGAACCAGGCATTGCGCGCCCGGCTGGCGGAAGTGGAGGCGGCGCTGGCACAGGAACGCGAGGACGGGCAGCGTAAAGTCGCCTGGTGTGACTGCGTGGAACACCAGGCCGCTCTCACCCTGCGATCCGAGAGGGCCCTCGATGACATTCGCAATCAGGCGGGCCAGGGGGCGGCGCGCCTGCTGGATGAACAGAAGCAACTCAATGAGTCTTCGCGGCTGTTCAGCCAGAGCACGGTCTTCCTGGAGGCAGTCCGCAGCCAGGTCGAGGAGGTGGCGCGTTCTGCCGCCAGCGGGCAGGAGACGGTCAACAATCTCGACGAGGCGGTACAGGCGATCCACCAGTTCACCGACACCATCGCCGAGATCTCGGACCAGACCAACCTGCTGGCACTCAATGCCGCCATCGAGGCAGCACGGGCAGGAGAACAGGGCCGGGGGTTCGCGGTAGTGGCAGAGGAGGTACGCAGCCTGGCGGCCAAGACGGCGGACGCCACCGATCGCATCAAGGACCACGTGCAACGGGTGACCGGTTACGCCGACGAGACCAAGGCCGGCTTTGAAGGCATGGTCGATGCCAGCTCGCGCATGCTGGAGCAGACCGACCAGATCAACGACGTCATCGGCGAAGTCACCTATCTTTCGCAGGGCATGATCCAGACCATCAGCCGCAATGCGGCCGGCGCCTTCATCGAGGTGGTCAAGCTCGATCACATTCTCTACAAGTTGGCGATCTACAAGGTGCTCGCCGGCAAGAGCGACAAGTCGCCCGATGACTTCGCCAGCCACCATCATTGCCGGCTGGGCAAGTGGTATTTCGAGGGTGACGGTGCCCAGCTTGCCGGTTCGCCGGTCTATCAGCAGCTCGACGAGCCCCATGCCGTGGTGCATGAAGCCGGGGCGCGGGCGTTGCGCGCACGCCAGGCGGGCGATAACGAAGGGTGCCTGGCGGCACTGGAAGAGATGGAAGATGCCAGCGATCGCGTGATCACCCTGCTGGGAGAGCTGGAAGAAACCTATTACCAGCGGATGCTGGGTTCAGTGGATACCGGCGCCAGCAAGGTCGATCTGTTCTGAACCATCGCCGGATCTGCTGTTTCCTTCCACGCAGTCCGATGGTTTCGGGTGACCGGGAAAAGCGGGATGCCGGTTGACCCCCGTGCGGTCGGGACGTATGATCTTCCGCCTTCGCCGCGAGGCGCGTTCCTCGGGGTATAGCGCAGTCTGGTAGCGCGCCTGCTTTGGGAGCAGGATGTCGGGGGTTCGAATCCCTCTACCCCGACCAGGTTTGGCCCGACCAGATTGGGCAGCTGACCCCGGTGGTTTTCGTCCCAGGCGGGCAGAACATGCGCCCGTAGCTCAGTTGGATAGAGCAGCGGCCTTCTAAGCCGCGGGTCGCAGGTTCGAATCCTGCCGGGCGTGCCAGTACAATACAGCCAACCACGGCGTGGCCAGGTCGGTGGACAATCAGGTTTCGATGGTGGGTATAGCTCAGTTGGTAGAGCCCCGGATTGTGATTCCGGTCGTCGTGGGTTCGAGTCCCATTACCCACCCCATCTTCACGAGGGGCTGCGTTCGCAGCCCCTTTTTCGTTTAGAATTCCTGGCTTCCTGCCAGTTTTTGCCGAGGTGATCGAGCGATGTTTGACAAGTCCATGAAGATCGAGGGTTACGACGATGAGCTCTTTCGGGCCATCAGGGACGAGGAGCGCCGTCAGGAAGACCACATCGAGCTGATTGCCTCGGAGAACTATTGCAGCCCGCGGGTGATGGAGGCCCAGGGGTCGGTACTCACCAACAAGTATGCCGAGGGCTACCCGGCCAAGCGCTACTACGGCGGCTGCGAATACGTCGATCGCGCCGAGCAACTGGCCATCGACCGTGCCAAGGCCCTGTTCGGCGCCGACTACGCCAATGTGCAACCGCATTCGGGCTCGCAGGCCAATGCCGCGGTGTACATGGCGCTGTGCCAGCCGGGAGACACCGTGCTGGGCATGGCGCTGGCGCACGGTGGTCACCTGACCCACGGAGCCAGGCCCAACTTCTCGGGCAAGATCTACAACGCGGTGCAGTACGGCCTGGACCCCGAGACGGGCGAGATCGACTACGAGGAAGTCGAGCGTCTGGCCCGGGAACACAAGCCGAAGATGATCGTGGCCGGTTTCTCCGCCTATTCGCGCATCGTCGATTGGCAGCGATTCCGTGAGATCGCCGACAGCGTGGGTGCCTGGCTGATGGTGGACATGGCACACATCGCCGGCCTGGTCGCTGCCGGAGTCTATCCCAGCCCGGTGCAGATCGCCGATGTCACCACCACCACCACGCACAAGACGCTGCGTGGTCCGCGCGGTGGCCTGATCCTGGCGCGCGCCAACGAGGAGGTCGAGAAGAAGCTCAACTCCGCGGTCTTCCCGGGCATCCAGGGCGGTCCGCTGATGCACGTCATCGCTGCCAAGGCGGTGGCCTTCAAGGAGGCCATGGAGCCCGAGTACGTCGAGTACCAGAAGCAGGTGGTGCGCAATGCGCAGGTCATGGCGCAGGTGTTCATCGAGCGCGGCTACGACGTGGTCTCGGGCGGCACCGACGATCACCTGTTCCTGGTCAGCTTCATCGAAGCCGGGCTCACCGGCAAGGACGTGGATGCCTGGCTGGGCGCGGCCAACATCACGGTCAACAAGAATGCGGTGCCCAACGATCCGCAATCGCCCTTCGTCACCTCGGGCATCCGTGTCGGCACGCCGGCGGTGACCACCCGTGGTTTCGGCGAGGACGAGTGCCGCCAGCTCGCCAGCTGGATGTGCGACGTGATCGACGGGCGTGGCGATACCGCAGTGATCGAGCGGGTCAAGGGCCAGGTGCTCGATCTGTGCACCCGCTACCCGGTGTACCGGGGCTGAGCGGAGGCGGCCGGTGCGCTGTCCCTTCTGCGGCGCCCAGGACACCAAGGTGGTGGACTCGCGCCTGCACGGCGACGGTGACCAGGTGCGCCGTCGCCGCCAGTGCACGGTCTGCAAGGAACGCTTCACCACCTACGAAACCGCCGAGCTGAACCTGCCCCGGGTGGTCAAGAGCGACGGCCGTCGGGTCAACTTCGACGGGCGCAAGCTGCGCGCGGGCATGGACCGCGCGCTGGAGAAGCGCCCGGTGGCCACCGAGGCGGTGGACGCGGCGGTCAATCACATCACCCGCAAGCTGATGTCGCGTGGCGAGAGCGAGGTGCCCTCCAAGCTGATCGGCGAGCTGGTGATGGAGGAGCTCAAGGCACTCGACCAGGTGGCCTACGTGCGCTTCGCCTCGGTGTACCGCCAGTTCGAGGATGTGCAGGCCTTCAGCGAGGAGGTCGAGCGTCTGCGCCAGGAGCCGTCGCCCGAGGCGCGCCGCGCCCAGCTCGACCTGCTGGACAGGGAGAAATGAGCGCCGGTTTCGACCGCGCCGATCACGCCTTCATGGCCCGCGCCCTGCAATTGGCGCGCCGCGGCCGCTACACCACCTTCCCCAATCCGCGCGTCGGTTGCGTGCTGGTGCGCGACGGCGAGATCGTCGGCGAGGGCTGGCACCGGCGCGCCGGCGAGCCACATGCCGAGCGCGTCGCCCTGGCCGCCGCCGGCGAACGGGCGCATGGGGCGACCGCCTATGTCACCCTCGAGCCATGCAGTCACCACGGTCGCACGCCGCCCTGCGCCGACGGCCTGATCGAGGCCGGGGTGACGCGGGTGGTCGCGGCCATGGAAGACCCCAACCCGCAGGTCGCCGGGGAGGGGCTGGCGCGGCTGCGCGATGCCGGTATCCGCGTCGAGACCGGCCTGCTCGAGGCCGATGCCCGGGCGCTCAATCCGGGCTTCATCCGCCGCATGCATGGCGAGCGCCCCTGGACGCGGCTCAAGCTGGCGGCCAGCCTCGACGGGCGCACCGCGATGGCCAGCGGCGAGAGCCAGTGGATCACCGGCCCCGCAGCGCGTCATGATGTGCAGTTCCTGCGTGCGCGCAGTGTGGCGGTGCTCACCGGCATCGGTACCGTGCTGGCCGATGATCCCTCGCTGAACGTGCGCCTGGACGGCGAGGCGTTGGGCCTGCCGTCCGACCTGCCGGTGCGCCAGCCGTTGCGCGTGGTGCTCGACAGCAGTGCGCGCACCCCGCCGGAGGCGCGTCTGCTGCGCCTGCCCGGATCGGTATTGATCTGTGTCGCCGAGGACGCGGACCCGGTGCGGGTCGCGGCCCTGGAAGCCGCCGGTGCCGAGGTCTGCCGCCTGCCGACCGACGCATCGGGACACCCCGCCTGGCCGGCGGTGATGGACACGTTGCGCGCGCGAGAGATCGACGAGGTGTTGCTGGAATGTGGTGCCACCCTGGCCGGTTCGGCGTTGCTGGCCGGGGTGGTCGATGAGCTTGTTCTCTACCTGGCGCCGCAACTGCTGGGCGATGCCGCGCGTGGCCTGGTGCATCTGCCCGGGGTCGAGCGGCTGGAGCAGCGTATCGAACTGGCGATGAACGACGTGCGCCAGGTCGGTGAGGATCTGCGCCTGACCCTGGCGGTCAGGCGATCCGGAACTGGCTGACCAGGGCGTGCAGCCGCTGTGACAGCGCGGTCAGGGCGTCGCTGGCGCGGTTGATTTCCTGGCTGCCTTCGGCCACTTCGCCGCTGGTGTGGCGGATGCGTTCGACGTTCTCGGACACTGCGGCGGTACTGGCGTGTTGCTCTTCCACCGCCTCGGTGATGTTGCGGTTGAGCTGTTCGATGCGCGACACCGCTTCTGCGATGGCGCTGAAGGTCTCGCCAGTGGCGCTGCCCTGTTGCACGGTGTGTACAGCCTGTTCCCGGCTCTGCGCCATCACCTCGGCGGCGGCGCGCGCGCCGGCCTGCAGGCGTTCGATCATTTCCTGGATCTCGGCGGTGGACTGCTGGGTGCGAGCGGCCAGGGTGCGTACCTCGTCGGCCACCACGGCGAAGCCGCGGCCCTGTTCGCCGGCACGCGCGGCCTCGATGGCGGCGTTGAGGGCCAGCAGGTTGGTCTGTTCCGCGATACTGCCGATCACGTCCAGCACGCTGCCGATGGCCTCGCTGTCACTGCTCAGGCGGGCGATGGTGGACGCCGCGGTCTCGACCTGCGAGGCGAGCTGTTCGATGGCGGCGACCGTCTCCTGTACCTGCTGTTGCCCGGCATCGGCCTGCTGACTGGCGCGGCGTGCATTCTCCAGGGTGCAGGTCGTGGCCTCGCTCACGTGGTCCATGTTGTGGCTCATCTGCTCGACCGCGGTGCCGACCTGGGCGGTGTCGTCCTGCTGCGCCTGGATACGGCCGATGTTCTCGCTGCTGATCGCCTGCAGGCGTCCGGCGGCTCCGGCCAGGTGGTCCACGGCCTCGCGCACCTCGCCGATGGTCTGGCGGATCTTGCCGGTGAAGCGGTTGAAGGCATGGCCGGTGCGGGCGATCTCGTCGTGTCCGCTGACTTCCAGCTCGGCGCTGAGGTCGCCGTCGCCATCGGCGATGTCTTCCAGGCGCTCCGCCAGGCGTGCGATGGGCCGGGCGATCAGGCGCAGGCTGAACAGGTAGGCGATGATCGCCACCAGCAGGCTGATGCCACTCATGCTGAGCGTGCTCCACTGGGCGGAACCCGTGACCTGGTCGATGTCTGCCAGTTGCTGGTCGATCAGGGCGCTGGTCTCGGTCTCGATCTCGCGGGCGAGTGCCATCAGGTGGTTGGCCGTGGCGTGGTAGTTCGCCCGTGCCGACTGCAGCTCGGTATGCCGTTCGAGGACCTGGGTGAACAGCCTGGCATTGTCCTCGAGGACACTGGCGATGGCCTCGGCGAAGGTGAGACTGGCGAAATGTCCCTTGCCGACCTTGCGGTCGTGCAGCAATTCGGCCTCTGCGACCTGCTCGAGGTAGATCTCCAGGTCGCTGTAGGCAGTGGCGGCACGCTCGCGCAGCGTGGCGTCACCGGGCTTTTCGAGCAGCTTTTCGAGCAGGAACAGCCGGCTCAGCAGGGCCAGTCGGGCGTCCGTGGTGGCCGAGACGATGGCCCATTCGGGACGGTCACGGGCATCGGTCTCGTCCTCTTCCGAACGGTTGATGTTCCACTCGGCATTGACCAGGGCCTGGCTGGCGATCTCTTCGGCGGCGATCAGCAGATCGCTGGTGTGTTCGAAGGCGGCCTCCAGGCCCGCGTGTTCTTCGCGAAACGCCTTGTCGAGCGCCAGCAGACGTTCCCGCGCCTGTTCGAATTCCTGCATCGAGCCATGGAGTTCCTCGAGGCGTTCGGCCGGGACCAGTCCCGAGGCCGAGAGCTTGCGAAAGGCTTCGCCGGTCAGGTGATGGCCCTCTGCGAGACCCTGTCGTGTGGCCTCGGGGCCCAGTCGCAGGGCGCGGTCGACGGCGATCATCTGTGTCTGTACGCCGCGGATGCCCTCGTTGATGGCTTCCGTGGTCTGGGCGACGGGGCCGCGTACCAGTTCGAGTGCCGTGCTCAGTTTTTGCACGGCAAGGTAGCCGACGGCGCCGCTGGCCAGGGTGAGCAGGGTGAGGGCCAGGTAGCCGATGCCGATCTTGTGGGATACGGAAGAGTGAAGATTCATTTTCAT

Protein sequences of DBSCAN-SWA_1

>NZ_AP012978|828935:838466|828935_830603_-|WP_043107457.1|DBSCAN-SWA
MAQYIFTMNRVSKIVPPKRQILRDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDTDYEGEARPQPGIKIGYLPQEPQLDPEKDVRGNVEEALGEVKQAMDELEKVYAAYAEPDADFDALAKRQAELENIIQAADGHNLERQLEVAAEALRLPPWDADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERFLHDYPGTVVAVTHDRYFLDNVAGWILELDRGHGIPWEGNYSSWLEQKEKRLEQEQKAEQARIKAMKQELEWVRSNPKGRHAKSKARLKQFDELQNQEFQKRNETNEIYIPPGPRLGDLVIEAKHLKKAYGDKVLYEDLSFNLPPGGIVGIIGPNGAGKTTLFRIMTGAEQPDDGELRIGPTVKIAAVDQSRDALDPNKTVWEEISDGQDIITVGNYQVQSRAYCSRFNFRGSDQQKKVGDLSGGERNRVHLAKLLKSGGNLLLLDEPTNDLDVETLRALEEAILAFPGCVVVISHDRWFLDRIATHILAFEGDSKVVWFEGNFADYEEDKKRRLGEDAVNPKRIKYKRIDA
>NZ_AP012978|828935:838466|833542_834784_+|WP_171816265.1|DBSCAN-SWA
MKIEGYDDELFRAIRDEERRQEDHIELIASENYCSPRVMEAQGSVLTNKYAEGYPAKRYYGGCEYVDRAEQLAIDRAKALFGADYANVQPHSGSQANAAVYMALCQPGDTVLGMALAHGGHLTHGARPNFSGKIYNAVQYGLDPETGEIDYEEVERLAREHKPKMIVAGFSAYSRIVDWQRFREIADSVGAWLMVDMAHIAGLVAAGVYPSPVQIADVTTTTTHKTLRGPRGGLILARANEEVEKKLNSAVFPGIQGGPLMHVIAAKAVAFKEAMEPEYVEYQKQVVRNAQVMAQVFIERGYDVVSGGTDDHLFLVSFIEAGLTGKDVDAWLGAANITVNKNAVPNDPQSPFVTSGIRVGTPAVTTRGFGEDECRQLASWMCDVIDGRGDTAVIERVKGQVLDLCTRYPVYRG
>NZ_AP012978|828935:838466|830659_831517_-|WP_043107460.1|DBSCAN-SWA
MSAQILDGKAIATDVREQVRLQVEQRVTEGQRPPGLVVVLVGENPASQVYVRNKQLACEKAGFKSELIQLPNDTSQEVLLELIDGLNARDDVDGILVQLPLPVQIDEHAVTERIHPDKDVDGFHPYNIGRLALRMPVLRPCTPKGVMTLLAHTGVELEGKDAIVLGQSNIVGRPMLLELLAARCTPTICHSRTRDLADKVRQADIVVAAVGVPNFVQGDWIKPGAIVIDVGINRLDDGSLCGDVDFEAAREVAGWITPVPGGVGPMTVATLLENTLQAAQLHTGT
>NZ_AP012978|828935:838466|831870_832965_+|WP_052199277.1|DBSCAN-SWA
MAELESENQALRARLAEVEAALAQEREDGQRKVAWCDCVEHQAALTLRSERALDDIRNQAGQGAARLLDEQKQLNESSRLFSQSTVFLEAVRSQVEEVARSAASGQETVNNLDEAVQAIHQFTDTIAEISDQTNLLALNAAIEAARAGEQGRGFAVVAEEVRSLAAKTADATDRIKDHVQRVTGYADETKAGFEGMVDASSRMLEQTDQINDVIGEVTYLSQGMIQTISRNAAGAFIEVVKLDHILYKLAIYKVLAGKSDKSPDDFASHHHCRLGKWYFEGDGAQLAGSPVYQQLDEPHAVVHEAGARALRARQAGDNEGCLAALEEMEDASDRVITLLGELEETYYQRMLGSVDTGASKVDLF
>NZ_AP012978|828935:838466|834797_835301_+|WP_043107462.1|DBSCAN-SWA
MRCPFCGAQDTKVVDSRLHGDGDQVRRRRQCTVCKERFTTYETAELNLPRVVKSDGRRVNFDGRKLRAGMDRALEKRPVATEAVDAAVNHITRKLMSRGESEVPSKLIGELVMEELKALDQVAYVRFASVYRQFEDVQAFSEEVERLRQEPSPEARRAQLDLLDREK
>NZ_AP012978|828935:838466|836420_838466_-|WP_081999803.1|DBSCAN-SWA
MKMNLHSSVSHKIGIGYLALTLLTLASGAVGYLAVQKLSTALELVRGPVAQTTEAINEGIRGVQTQMIAVDRALRLGPEATRQGLAEGHHLTGEAFRKLSASGLVPAERLEELHGSMQEFEQARERLLALDKAFREEHAGLEAAFEHTSDLLIAAEEIASQALVNAEWNINRSEEDETDARDRPEWAIVSATTDARLALLSRLFLLEKLLEKPGDATLRERAATAYSDLEIYLEQVAEAELLHDRKVGKGHFASLTFAEAIASVLEDNARLFTQVLERHTELQSARANYHATANHLMALAREIETETSALIDQQLADIDQVTGSAQWSTLSMSGISLLVAIIAYLFSLRLIARPIARLAERLEDIADGDGDLSAELEVSGHDEIARTGHAFNRFTGKIRQTIGEVREAVDHLAGAAGRLQAISSENIGRIQAQQDDTAQVGTAVEQMSHNMDHVSEATTCTLENARRASQQADAGQQQVQETVAAIEQLASQVETAASTIARLSSDSEAIGSVLDVIGSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAARTQQSTAEIQEMIERLQAGARAAAEVMAQSREQAVHTVQQGSATGETFSAIAEAVSRIEQLNRNITEAVEEQHASTAAVSENVERIRHTSGEVAEGSQEINRASDALTALSQRLHALVSQFRIA
>NZ_AP012978|828935:838466|835297_836443_+|WP_043107464.1|DBSCAN-SWA
MSAGFDRADHAFMARALQLARRGRYTTFPNPRVGCVLVRDGEIVGEGWHRRAGEPHAERVALAAAGERAHGATAYVTLEPCSHHGRTPPCADGLIEAGVTRVVAAMEDPNPQVAGEGLARLRDAGIRVETGLLEADARALNPGFIRRMHGERPWTRLKLAASLDGRTAMASGESQWITGPAARHDVQFLRARSVAVLTGIGTVLADDPSLNVRLDGEALGLPSDLPVRQPLRVVLDSSARTPPEARLLRLPGSVLICVAEDADPVRVAALEAAGAEVCRLPTDASGHPAWPAVMDTLRAREIDEVLLECGATLAGSALLAGVVDELVLYLAPQLLGDAARGLVHLPGVERLEQRIELAMNDVRQVGEDLRLTLAVRRSGTG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043107457.1|828935_830603_-	energy-dependent translational throttle protein EttA	A0A2K9L3Z8	Tupanvirus	4.9e-42	27.0
WP_043107460.1|830659_831517_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	8.1e-33	34.6
WP_052199277.1|831870_832965_+	CZB domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	3.8e-11	38.0
WP_171816265.1|833542_834784_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	6.5e-100	52.5
WP_043107462.1|834797_835301_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_043107464.1|835297_836443_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	7.0e-40	35.3
WP_081999803.1|836420_838466_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.1e-16	29.5

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_AP012978|1396488:1407132|DBSCAN-SWA
CATGGCTAAGGTTCGCGTGCACACCAACGGCAAGCTCTTCTTCGACTTCCGCTTCCAGGGCCGGCGTTACCGGGAATACACGGCACTGGCCGACACGGCACGCAACCGCCGCCTCGTGGAATCGGTGATCAGGAAAATAGACCGCGCCATCAAGGACGGATCCTTCCGGTATCAGGACTTCTTCCCGCCGGAAAACAGCCGCACCGTCAGCAGGCCCATCGCTTCGGCGACCAGCGATGCCGCGTCGGCCGAAGAACACCGCGCCTTGCCCGGCGCGACCCCTTGCGTTGCGACACCCGGTTTCAGCGAGTTCTTCGAACAGTGGTACATGGAGCGGGAAATCGGCTGGAAACGATCCTATCAGCAGAAGGTGGCCGACATCGGCAACAAGCACCTCATTCCCGCGTTCAGGGCGATGAAGATCGGCGACATCTCCAAGGCGGAATGTCTCGCTTTCCGCGCAAGCCTTGCAAAAGACAAAGGCCTTTCGCCATCCCGCATCAATGCCATCATGAACATATTGAGGCAGGTCCTGTCCGAGGCCGCCGAACGATTCGATTACACGATGCCGATCCGGGATCTGAAACCGCTGCGCCAGCCACGTTCGACAGTCAACCCCTTGTCGCTCGCCGAGGTACAGGCCTTCCTTTCGGCGGTTCCGGAGCGTCATCGTCCCTATTACGTCACCGCTTTCTTCACAGGACTGAGAACCTCCGAACTCAACGGACTGAAGTGGAAATACGTTGATCTGGAACGCCGACAAATCGGCGTCTTCGAGACATTTGTCTATGGCAAACAGGACACCACAAAAACCGATGGCTCCCAGCGCTACGTCGAGATGTCGTCCCCCGTGGTGGAGGCGCTTTCAAGACAGCAAGACCTCACCCGGGGTCGATCCGACTACGTTTTCTGCAGCCGGAACGGCCAACCGCTGAACTACCGCAACATGGCGCGTCGCGTCTGGTACCCCACGTTGGAAAAGGCCGGCCTGGAACGTCGCCGCCCCTATCAGACCCGCCACACTGCATCCACGCTCTGGCTCGCGGCCGGCGAGTCGCCAGTGAGCCGCCCCGGGTTTCCCGGAGACTCCATTTCTTGAGAGGATAGAGTCTATGGATACGAGCAAGAGATATTCCCCTGAGGTCCGGGAACGGGCGGTTCGCATGGTGTTTGATCATCAGGCCGAGCGTGATCAAGGACTGCGTGAGGGTCTGACGACGTCGGAGCGCGAGCGGCTCAAGGCCTTGGAACGGGAGAACCGGGAGCTGAGGCGGGCCAACGAGATTCTGAAGACGGCGTCGGCTTTTTTTGCCCAGGCGGAGCTCGACCGCAAACTGAAGAGATGATCGCGTACATCGACGATCACAGGGATCGTTACGGGGTCGAGCCGATCTGCGCGGTGCTGCCGATCGCCCCGTCCACCTACTATGAGCACAAGGCCCGTGAGGCCGATCCACAGCGACTGCCGCGGCGATTGCAGCGGGATCGCGCCCTGTCAGACGAGATTCGACGGATCTGGGAAGAGAACTTCCAGGTGTACGGTGCCAGGAAGGTATGGCGGCAGCTCAACCGGGAAGGCATCGAGGTAGCCCGCTGCACGGTGGAACGTCTGATGCGTGTCATGGGGTTGCGGGGTGTGGTGTGAGGCCGCCGTTGCCGGACAACGATCGGCGACACGACGGCGGAACGACCACTGGACCGGGTGAAGCGGCAGTTTACTGCCACCCGCCCGAATCAGTTGTGGGTGGCGGACATTACCTACGTGGCGACTTGGACAGGGTTTGTCTATGTGGCGTTTGTCGTGGACGTCTATGCCCGACGGATCGTGGGCTGGCGTGTCTCCCGGTCGCTGAAGACCGACCTGGTGCTGGATGCGCTGGAGCAGGCGCTATGGTCGCGCCAGGACACAGAGGGCCTGGTGCACCACAGTGACCGAGGCTGTCAGTACCTGTCGGTGCGCTACACGGAGCGCCTGGCCGGGGCCGGCATTGATGCCTCGGTCGGTAGCCGAGGGGACTCCTATGACAACGCTCTGGCAGAGACGATCAACGGTCTGTACAAGGCCGAGGTTATCTACCGGCGAGGCCCCTGGAAGCATAGGGAGGCGGTCGAATATGCCACTTTGGAGTGGGTGGACTGGTTCAACCACCGGCGGCTGCTGGAGCCTATTGGCAACGTGCCACCGGCGGAGTTGGAAGCGGCGTATTATCGCCAACAGAAAGAGTCTGCCAAGGCGGCCTGACTCAAACAAAACAGTCTCCGGAATATCCGGGGCGGTTCACTGATCGGGTGCCAGATCGGCCACCCGCCGACGCGGATGCAGGCCCGCCACGTGCAGAATCTCGCAACAGAGGTAGTTGCCGATCCCCGCGAGCACCGACTGATCCTGCAACAGCCCGGCCAGGGCGCGTCGCGGGTGCTGCAGCAGGCACGCCTTCACCTGTGAAGCATCAACGCCCGGATCGAGCAGTTCCGGCCCCAGACGCGACAGGTAAGGGTGCGCGCCGACGGCTTCCTCATCGAGCATCTCGATCTCGGTGGCGCTATAGAGCAAGGCCAGATGACGGTGGGTCCCCAGCATCAGGCGCAGCCGGCGGCGGGACGATGGCAGCACCCTGCCCTCCACCACTTCCCAGCGGCCATAGAGCTGATTATGGGTATAGAGCGTCATGCCATTGTCGAAACGGGTGAGCAGCGCCTTGCCGCGCGCCATCACCGACAGTACCCGGGCGCCTGCGAGCCGGTCCTCCCAACCCTGCAGACCCGGCACCGCAAAGCGAACCTGTTGCAAGTGCTGGCCGGCAAGGACATCGGCCAGGCGATCGGCAGTACGCTTGATCTCGGGACCTTCGGGCATGAGGCATCGCGACGGGCGGACACACAAAGGCCCCGACGAGCGGGGCCCTGCAAGACCCTCCGTGGGCGGGAGGGCAGATCGATACTGGTCGGAGCGGGGAGATTCGAACTCCCGACCCCCACAACCCCATTGTGGTGCGCTACCAGGCTGCGCTACGCTCCGAAAACGAGACGCGCATGCTAGAGGGGCATGCGGCGTTTGTCAATTTGAAAACGGCCCGATCAGGCCTCGAGCAATTGCAGGATGGCCTCGAGCTCCTCGCGCAACTCGCGGACCAGTTGCGGATCGGCCCCCTTGGCCTTGCCGCTCTCGCCGTCACCCTCTTCCAGACGCTGGCGCGCCCCGCCGATGGTGAAGCCCTGCTCGTAGAGCAGGCTGCGGATCTGGCGGATCAGCTCGACGTCGTGGCGCTGGTAATAGCGCCGGTTGCCGCGCCGCTTGACCGGCTTGAGCTGGGGGAACTCCTGCTCCCAGTACCGCAGCACGTGCGGCTTGACCTGGCACAGCTCGGCCACCTCACCGATGGTGAAATACCGCTTGCCGGGGATCGGCGGCAGTTCCAGATTGCTGCTCTCGGGGTCGAGCATGAGCTGCTACCTCAACCGGTCCGCTGCTCGGCCGCCGCAGCCTGCTGCTGGGTATAGGCCTCGACCCGGGCCTTGAGCTTCTGGCCGGGCCGGAAGGTGACCACACGGCGCGCGGAAATGGGGATCTCCTCGCCGGTCTTGGGGTTGCGCCCGGGCCGCTGGCGTTTTTCTCGCAGGTCGAAGTTTCCGAAGCCCGACAACTTCACCTGGCGCCCGTCCTCCAGGGCCTGGCGAATCTCCTCGAAGAACATCTCCACCATTTCCTTGGCCTCGCGCTTGTTCAGCCCGAGCTCCTCGAACAGATGTTCAGCCATGTCGGCCTTGGTCAATGCCATAACGATAACCTAGTCTCTCAACGTAGCGGACAATTCCCCGGCCAGCGCCTCCAGCACGGCCTGGCCGGCACGTTCGACTTCCTGTTCAGTAAGAGTGTGCGAAGAATCCTGTAAAATCAAGCTCAAAGCGAGACTTTTTCGATCGGAATCTACATTCTCGCCAGTATAGACGTCAAACAACTGGATCTCGCGCACAATTTCAGGCGCCGCCCTGCGCGCCACCTCGTGTACCTGGTCCCAGCTCGTCTCGCGCGCCACCACGATGGCAAAGTCGCGGCGAATGGCCGGGTACTTGGACAAGGGCGCGAAGGCCGGCAGGCGCCCTTCAGCCAGCTCTTCGAGCGAAACCTCGAAGACATAGGTCGCCGGCAGGTCCAGCCGCTGCTGCAGCTGCGGATGCACCGCCCCGATCCAGCCGATGGCCTGCCCGTGATAGAGCACCCGCGCGGTCTGCCCCGGGTGAAGGGCCGGATGCTCGGCTGCCACAAAACCGAAGTCTTGCGCCGGCGCGACCTGGGTGAGCACGGCCTCCAGGTCGCCCTTGAGATCGAAGAAATCGGCCTTGCGCGCGGCCTGCCCCCACTGGGTGTCGACCACCGGGCCGCAGATCAGTCCGCCGAGGCGCGGGCGCTGTGCGATCTCACCGGCGATGCGCTCGAAGGTGAGGCCCGATTCGAAGATTCGCACCCGTTCCTGCTGGCGCGCCAGGTTGTGTCGTGCCGCAGCCAGCAGTCCGGGCCACAGGCTGGCACGCATCACCGACATGTCGGCGGAGATGGGATTGCTCAAGCGCACCGGGGCGATGTCCGGGGCGACCTGCTCGGCCATCTCCGGGCTGATGAAGCTGTAGGTGATGACCTCGTGATAGTCCCGGTCGACCAGGGTGTCACGCGCGCGGTCGAGACGGAAGGCCGCCTCGGGCTGCGCGGCAATGGTGACCGGCGCTGCGTGCAGACTGGCCGGGATGTTGGCATAGCCGTGAATACGCCCCAGCTCCTCGATCAGGTCCACCTCGATGGCGATATCGAAACGGCTGCCCGGCGGCGTCACCTCCCAGCCCTCGTCGACGCCCCGCACCTGCATGCCCAGGCGCTCGAGGATGTCCTTCACCTCGGCGTCGGCCAGTTCGATACCCAGGATGCGCGGGATACGCGCACGGCGCAGGCGGACGGGTCGCCGCACTGGCAGCTGCGCCTCACTCACCGTCTCGCTGACCGGCCCGGCCTGGCCGCCGGCGATCTCGAGCAGCAGCGCGGTGGCATATTCCATGGCGCGCACCGGGAGCTCGGGATCGACGCCGCGCTCGAAACGGTGTGACGAATCGGTATGCAGACCATAGCTGCGCGCCTTGCCGGCGATCGCCAGCGGCGCGAAGAAGGCGGCCTCCAGCAACACGTTGCGGGTATCGCCGCTCACCCCGCTGTCCTCACCGCCCATGATGCCGGCCAGGGCCAGCGGCCCCTTGCTGTCGGCGATCACCAGGGTGTCGTCGCGCAGGGTCACCTCGCTACCGTCGAGCAAGGTCAGCGCCTCGCCATCCTGCGCCATGCGCACGGTAACCCCGCCTTGCAGCCGATCCAGATCGAACCCGTGCATGGGCTGGCCGAGTTCGAGCATCACGTAGTTGGTGACATCCACCACCGGGGAGATGGCGCGCACGCCGCTGCGGCGCAAGCGCTCGACCATCCACAGCGGGGTCTGCGCAGCGGGATCGATGCCACGGATCACCCGGCAGACATAGCGGGGGCAGGCCTCGGGGGTTTCCACCGTCACCGGGAAGGTGTCGGTGAGATCGGGATTGACCGGCTCGATGACCTCGCCGCGCAGCGGCGCCCGGTTGAGCACCGCTACCTCGCGCGCAATGCCGGCCACGCTCAGGCAGTCGCCGCGATCCGGCGTCAGGTCCACGTCGATGCAGGCATCGTCCAGATCCAGCCAGGCACGGAAATCCTTGCCCACCGGGGCGTCTTCCGCCAGTACCATGACGCCGTCGGACGATTCCGCCAGTCCCAGTTCGGCCGCCGAGCAGATCATGCCCTGCGACAGGACACCGCGCAGTTTCGACTTCTTGATCTTGAAATCACCCGGCAGGCGCGCGCCCACCGTGGCCACGGGCACCTTCTGCCCGGCCGCCACGTTGCGTGCGCCGCACACGATCTGCAGGGGCTCATCGCCGTCCACGTCCACCCGACAGACGCTGAGCTTGTCGGCATCGGGGTGCTTCTCGCAAGAGAGCACGTGGCCGACCACCACGCCACTGAACGCCGGCGCGGCCGGCTCCACCGAATCCACCTCCAGGCCGGCCATGCTGAGCTGATCGGCCAGCTCGGCGGTGGAGATATCGGGATTCACCCATTCACGCAACCAGGCTTCGCTGAATCGCATCGTTAACTGGTCCTTGAGACTTGCATGTCAATCTTCACCACAAAGCGCACAAAGGGTACGAAGAAGGTCGAGAGCCCGGTCGCTGGTCTTCCCGTCACCCTTCCGCGCACAGTAGCGTTCACCTCACATCGCCCTGCTGTCCTTCGTGTGCTTCGTGAACTTCGTGGTTTTTCTGTTCAGGCAAACTGCCGCAGGAAGCGCAGGTCGTTCTCGAAGAACAGCCGCAGGTCGTTGACGCCGTAGCGCAACATGGCCAGGCGCTCCACCCCCATGCCAAAGGCGTAACCGGTGTAGCGTTCGCTGTCGATGCCGACATGGCCCATCACCTCGGGGTGGATCATGCCGCAGCCCAGCACCTCCAGCCAGCCAGTGCCGGAACACACCCGGCAACCTTCCCCGCTGCACATCACGCACTGGATATCCACCTCCGCCGAAGGCTCGGTGAAGGGGAAATAGGACGGGCGGAAACGTACGTCCAGATCCTCGCGCTCGAAGAAGGCGTGCAGGAAGGCAATGAGAATGCCCTTCAAATCGGCAAAGGTGACCTGCTCGTCCACCATGAAACCCTCGACCTGATGAAACATGGGCGTGTGGGTCAGGTCGGAGTCGCAGCGATAGACGCGCCCCGGTGCAATCACCTTGAGCGGCGGCTCGGCGCCCTTCATCACCCGGATCTGCACCGGCGAGGTATGGGTACGCAGCAGCAGGCCATCGTCGAAATAGAAGGTGTCGTGCATGGCCCGCGCCGGGTGATGGGCAGGGATGTTGAGCGCCTCGAAGTTGCGGAAGTCGTCCTCGATCTCGGGACCTTCCGCCACCTGGAAACCGGCACCGCCAAAGATCTCCTGGATGCGCCGCATGGTGCGCGTCACCGGGTGCAGACCGCCCCGCCCCGGGCCACGCCCCGGCAGGGTGACGTCGATGCGCTCGGCGGCCAGGCGCTCGGCCAGCGCGACGGCCTCCAGGGCCTGGCGGCGCGCCTCGATGGCCTGTTGCAGGGCCTGCTTGGCACGGTTGATCGCCTGCCCGGCCGCAGGGCGCTCTTCCTTGGGGAGCTTGCCGAGCTGCTTGAGCTGCCCGGTAAACACCCCGCTCTTGCCCAGGTAGCGCACCCTCACCTCGTCGAGCGCACGCAGGTCGGCCGCGGCCTCCACCGAGGCCTGCGCCTCGTCCAGCAGCTGTTCCAGTTCTGTTGCCATGGCTTTCTCGAATACGGTTGGAGCTTTCACCGAAAAGGGGGAAGCCAGACGACTTCCCCCTCTCCAGACCGGCAGTCGGACATGCCGGTGACGATCAGCCTGCGAGGGCCGCCTTGGCCTTCTCGGCGAGTTGGCTGAAGGCGGGCATGTCGTGTACCGCGATATCGGCCAGCATCTTGCGATCGATGGCGATACCGGCCTTGTTCAGGCCGTCGATCATGCGGCTGTAGGACAAGCCGTTCATGCGCGCCGCCGCATTGATACGCTGGATCCACAGCGCGCGGAACTGGCGCTTCTTGACCTTGCGGTCGCGATAGGCGTACTGGCCGGCCTTGATGACGGCCTGCCTGGCAACCCGGAACACCTTGCGGCGGGCACCGTAGTAGCCTTTGGCCTGCTTGAGAACCTTCTTGTGCTTGGCGTGTGCGGTAACGCCGCGTTTCACTCTTGGCATGGGTCAGTCCTCCGGTCAGGCGTAGGGGATCATGCGGCGGGCCGCGGCCACGTCGTTCTTGTGCAACATGGACGGCGCGCGCAGGTGACGCTTACGCTTGGTGGATTTCTTCGTCAGGATGTGACGGCGGTGCGACTGGTTGCGCTTGATGCCACCGGCGGTGACACGGAAGCGCTTGGCTGCACCCCGGAGGGTCTTGATCTTGGGCATTTTGCTGTCTCCTGTATCGAGGTTGCTTCAGGGTGACCCAGGCTCAGGGTGACCCAGGCAATGCCTTGGGCCCGGCCACCCGTGGCGGCGATGCCGCCGGATTCGGTATCACTTCTTCAGCGGACTGAGCACCATCACCATCTGGCGCCCTTCCATGATCGGTCGCTGCTCCACCTGGGAGATGTCGGCCAGGTCACGCTCGACGCGCTGGAGCATCTCCAGCCCAAGCTCGCGGTGGGCATGCTCGCGACCACGAAAACGCATGGTCACCTTGCACTTGTCGCCGTTTTCGAGAAACCGCCTGAGGTTGCGCAGCTTGACCTTGTAGTCGCCGATGTCGGTTCCGGGCCGGAACTTGACCTCCTTGACCTGGACCTGTTTCTGCTTCTTGCGCGCCTCCTGCCGCTGTTTCTTCTGCTCGAACACGAACTTGCCATAGTCCATGATGCGGCAGACAGGCGGCTCGGCGTTGGGAACGATCTCCACCAGATCGAGCCCGGCGCCGTCGGCGATACGCTGGGCCTCCTCGAGGCTGACGATCCCGATCTGTTCCCCATCTGCGCCGATGAGCCTGACCTCGGGGGCGGTGATGTCTCCGTTCAGACGATTGCGCTTTTCTTGTTTTGCGATGTCCTGATTCCTCCAAAAAACAAAACCGCCCGACAACAGGGCATGCCTTGGGGCATGCTTGCTGATCGGGCAGCTGGTCAGGACCGCTGGGCGATCTCCTGCTCGAGATGCCCGGCAAGGTCGTCGAGGGGCATGACCCCCAGATCCTTGCCGTCACGGGTTCGCACCGCGACGCTGCGGCCCTCCACTTCACGGTCCCCCACCACCAAGAGGTAGGGCACCTTCTGCAAGGTATGCTCGCGAATTTTAAAACCGATCTTCTCGTTTCTCAAGTCCGTTTCCACGCGAATGCCGCGATCCTGCAGGAATTGCGCGACTTCGCCGACGAACGGCGCCTGGCGGTCGGTGATGTTCATCACCACCGCCTGCACCGGCGCCAGCCACAGCGGCAGCGCACCGGCATAGTGCTCGATGAGGATGCCGATGAAGCGCTCCAGCGAGCCCAGGATGGCGCGGTGCAGCATCACCGGCGTCTTCTTGCTGTTGTCCTCGGCGACATAGGTCGCGCCCAGGCGCTCGGGCATGGAGAAGTCGAGCTGGATGGTACCCAGTTGCCAGACCCGACCCAGGCAGTCGCGCAGGGCGAATTCGATCTTGGGCCCATAGAAGGCCCCCTCGCCCGGCTGCAGTTCCCAGTCCACGCCACGTTCGTTCAGCGCGTCCTCGAGCGCCTGCTCGGCCTTGTCCCACAGTTCGTCCGACCCCACACGCTGCTCGGGGCGCGTGGACAGCTTGATCTGCACATCCTCGAAGCCGAAGTCGCGATAGACCTCGAACAGCAGGTCGATGAAGGCCAGCACCTCGGGCAGGATCTGCTCTTCGGTGCAGAAGATGTGCGCATCGTCCTGCACGAAGTTGCGCACCCGCATCAACCCATGCAGGGTGCCCGAGGGCTCGTTGCGGTGGCAGGAACCGAATTCGGCCAGACGCAGCGGCAGGTCACGGTAGCTCTTGAGCCCCTGGTTGAAGATCTGAATGTGTGCCGGGCAGTTCATCGGCTTGATCGCGTAGTCGCGATTTTCCGAGTGCGTGGTGAAGATCATGTCGCCGAACTTGTCCCAGTGGCCCGACTTCTCCCACAGGCTGCGATCGATCACCTGCGGGGTGTGCACCTCCTGGTAGCCATGCGCACGCAATTTCTCGCGGATGTAGTTCTCGATCGTGAGATAGATGCGCCAGCCCTTGTCGTGCCAGAACACCATGCCCGGCGCCTCTTCCTGGGTGTGGAACAGGTCGAGCTGGCGGCCGATGCGTCGGTGATCGCGCTTCTCGGCCTCTTCCAGGCGCTTGAGATAGGCCTTGAGCTCCTTCTTGTCGCGCCACGCCGTGCCGTAGATGCGTTGCAGCATGGCGTTGTTCGCGTCCCCCCGCCAGTAGGCGCCGGCCAGCTTCATCAGCTTGAAGGCCTTGGGCAGCTTGCCGGTGCTGGGCAGATGCGGACCACGGCAGACGTCGAACCAGTCGCCCTGACGGTAGACCGAGATCTCCTCGCCCTCGGGGATGGCGTCGATGATCTCGACCTTGTAGTGCTCGCCGATCTCGCTGAAGACCTTCTTCGCCTCCTCGCGGTCCCAGACCTCGCGCTCGATGGGCAGGTCGCGGCCGACGATCTCGCGCATGCGATCCTCGATCTTCTGCAGATCCTCGGGCGTGAAGGGCTCCTCGCGCGCGAAGTCGTAGTAGAAGCCGTCCTCGATCGCCGGGCCGATGGTCACCTGGGTGCCCGGATAGAGCTCCTGCACCGCCTGCGCCATCACGTGCGCCGCATCGTGGCGGATCAACTCCAGCGCCTCCTCGTCGCGCGCGGTGACGATCGCCAGATCGGCATCACGGTCGATGGTACGCGAGAGATCCACCAGTTCGCCGTCGAGCTTGCCGGCGAGTGCGGCCTTGGCCAGCCCCGGACCGATATCAGCGGCCACCTCGGCGACCGTCACCGGGTGGTCATAGGCGCGCTGGGAACCGTCGGGCAACGTGATGACAGGCAT

Protein sequences of DBSCAN-SWA_2

>NZ_AP012978|1396488:1407132|1404622_1405144_-|WP_043109387.1|DBSCAN-SWA
MAKQEKRNRLNGDITAPEVRLIGADGEQIGIVSLEEAQRIADGAGLDLVEIVPNAEPPVCRIMDYGKFVFEQKKQRQEARKKQKQVQVKEVKFRPGTDIGDYKVKLRNLRRFLENGDKCKVTMRFRGREHAHRELGLEMLQRVERDLADISQVEQRPIMEGRQMVMVLSPLKK
>NZ_AP012978|1396488:1407132|1403944_1404304_-|WP_043107934.1|DBSCAN-SWA
MPRVKRGVTAHAKHKKVLKQAKGYYGARRKVFRVARQAVIKAGQYAYRDRKVKKRQFRALWIQRINAAARMNGLSYSRMIDGLNKAGIAIDRKMLADIAVHDMPAFSQLAEKAKAALAG
>NZ_AP012978|1396488:1407132|1402827_1403850_-|WP_043107932.1|tRNA|DBSCAN-SWA
MATELEQLLDEAQASVEAAADLRALDEVRVRYLGKSGVFTGQLKQLGKLPKEERPAAGQAINRAKQALQQAIEARRQALEAVALAERLAAERIDVTLPGRGPGRGGLHPVTRTMRRIQEIFGGAGFQVAEGPEIEDDFRNFEALNIPAHHPARAMHDTFYFDDGLLLRTHTSPVQIRVMKGAEPPLKVIAPGRVYRCDSDLTHTPMFHQVEGFMVDEQVTFADLKGILIAFLHAFFEREDLDVRFRPSYFPFTEPSAEVDIQCVMCSGEGCRVCSGTGWLEVLGCGMIHPEVMGHVGIDSERYTGYAFGMGVERLAMLRYGVNDLRLFFENDLRFLRQFA
>NZ_AP012978|1396488:1407132|1398765_1399344_-|WP_052199372.1|DBSCAN-SWA
MPEGPEIKRTADRLADVLAGQHLQQVRFAVPGLQGWEDRLAGARVLSVMARGKALLTRFDNGMTLYTHNQLYGRWEVVEGRVLPSSRRRLRLMLGTHRHLALLYSATEIEMLDEEAVGAHPYLSRLGPELLDPGVDASQVKACLLQHPRRALAGLLQDQSVLAGIGNYLCCEILHVAGLHPRRRVADLAPDQ
>NZ_AP012978|1396488:1407132|1404319_1404514_-|WP_043107935.1|DBSCAN-SWA
MPKIKTLRGAAKRFRVTAGGIKRNQSHRRHILTKKSTKRKRHLRAPSMLHKNDVAAARRMIPYA
>NZ_AP012978|1396488:1407132|1399565_1399931_-|WP_043107927.1|DBSCAN-SWA
MLDPESSNLELPPIPGKRYFTIGEVAELCQVKPHVLRYWEQEFPQLKPVKRRGNRRYYQRHDVELIRQIRSLLYEQGFTIGGARQRLEEGDGESGKAKGADPQLVRELREELEAILQLLEA
>NZ_AP012978|1396488:1407132|1400275_1402651_-|WP_043107930.1|tRNA|DBSCAN-SWA
MRFSEAWLREWVNPDISTAELADQLSMAGLEVDSVEPAAPAFSGVVVGHVLSCEKHPDADKLSVCRVDVDGDEPLQIVCGARNVAAGQKVPVATVGARLPGDFKIKKSKLRGVLSQGMICSAAELGLAESSDGVMVLAEDAPVGKDFRAWLDLDDACIDVDLTPDRGDCLSVAGIAREVAVLNRAPLRGEVIEPVNPDLTDTFPVTVETPEACPRYVCRVIRGIDPAAQTPLWMVERLRRSGVRAISPVVDVTNYVMLELGQPMHGFDLDRLQGGVTVRMAQDGEALTLLDGSEVTLRDDTLVIADSKGPLALAGIMGGEDSGVSGDTRNVLLEAAFFAPLAIAGKARSYGLHTDSSHRFERGVDPELPVRAMEYATALLLEIAGGQAGPVSETVSEAQLPVRRPVRLRRARIPRILGIELADAEVKDILERLGMQVRGVDEGWEVTPPGSRFDIAIEVDLIEELGRIHGYANIPASLHAAPVTIAAQPEAAFRLDRARDTLVDRDYHEVITYSFISPEMAEQVAPDIAPVRLSNPISADMSVMRASLWPGLLAAARHNLARQQERVRIFESGLTFERIAGEIAQRPRLGGLICGPVVDTQWGQAARKADFFDLKGDLEAVLTQVAPAQDFGFVAAEHPALHPGQTARVLYHGQAIGWIGAVHPQLQQRLDLPATYVFEVSLEELAEGRLPAFAPLSKYPAIRRDFAIVVARETSWDQVHEVARRAAPEIVREIQLFDVYTGENVDSDRKSLALSLILQDSSHTLTEQEVERAGQAVLEALAGELSATLRD
>NZ_AP012978|1396488:1407132|1396488_1397586_+|WP_052199371.1|integrase|DBSCAN-SWA
MAKVRVHTNGKLFFDFRFQGRRYREYTALADTARNRRLVESVIRKIDRAIKDGSFRYQDFFPPENSRTVSRPIASATSDAASAEEHRALPGATPCVATPGFSEFFEQWYMEREIGWKRSYQQKVADIGNKHLIPAFRAMKIGDISKAECLAFRASLAKDKGLSPSRINAIMNILRQVLSEAAERFDYTMPIRDLKPLRQPRSTVNPLSLAEVQAFLSAVPERHRPYYVTAFFTGLRTSELNGLKWKYVDLERRQIGVFETFVYGKQDTTKTDGSQRYVEMSSPVVEALSRQQDLTRGRSDYVFCSRNGQPLNYRNMARRVWYPTLEKAGLERRRPYQTRHTASTLWLAAGESPVSRPGFPGDSIS
>NZ_AP012978|1396488:1407132|1405221_1407132_-|WP_043107936.1|tRNA|DBSCAN-SWA
MPVITLPDGSQRAYDHPVTVAEVAADIGPGLAKAALAGKLDGELVDLSRTIDRDADLAIVTARDEEALELIRHDAAHVMAQAVQELYPGTQVTIGPAIEDGFYYDFAREEPFTPEDLQKIEDRMREIVGRDLPIEREVWDREEAKKVFSEIGEHYKVEIIDAIPEGEEISVYRQGDWFDVCRGPHLPSTGKLPKAFKLMKLAGAYWRGDANNAMLQRIYGTAWRDKKELKAYLKRLEEAEKRDHRRIGRQLDLFHTQEEAPGMVFWHDKGWRIYLTIENYIREKLRAHGYQEVHTPQVIDRSLWEKSGHWDKFGDMIFTTHSENRDYAIKPMNCPAHIQIFNQGLKSYRDLPLRLAEFGSCHRNEPSGTLHGLMRVRNFVQDDAHIFCTEEQILPEVLAFIDLLFEVYRDFGFEDVQIKLSTRPEQRVGSDELWDKAEQALEDALNERGVDWELQPGEGAFYGPKIEFALRDCLGRVWQLGTIQLDFSMPERLGATYVAEDNSKKTPVMLHRAILGSLERFIGILIEHYAGALPLWLAPVQAVVMNITDRQAPFVGEVAQFLQDRGIRVETDLRNEKIGFKIREHTLQKVPYLLVVGDREVEGRSVAVRTRDGKDLGVMPLDDLAGHLEQEIAQRS
>NZ_AP012978|1396488:1407132|1399942_1400266_-|WP_043107929.1|DBSCAN-SWA
MALTKADMAEHLFEELGLNKREAKEMVEMFFEEIRQALEDGRQVKLSGFGNFDLREKRQRPGRNPKTGEEIPISARRVVTFRPGQKLKARVEAYTQQQAAAAEQRTG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1389590:1389605	attL	NA	NA	NA	NA
WP_052199371.1|1396488_1397586_+|integrase	site-specific integrase	I6PDJ1	Cronobacter_phage	7.5e-15	36.4
WP_052199372.1|1398765_1399344_-	hypothetical protein	NA	NA	NA	NA
WP_043107927.1|1399565_1399931_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_043107929.1|1399942_1400266_-	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	8.6e-12	40.0
WP_043107930.1|1400275_1402651_-|tRNA	phenylalanine--tRNA ligase subunit beta	A0A1L3IZU3	BeAn_58058_virus	1.2e-06	27.6
WP_043107932.1|1402827_1403850_-|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	4.8e-32	36.5
1403568:1403583	attR	NA	NA	NA	NA
WP_043107934.1|1403944_1404304_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_043107935.1|1404319_1404514_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_043109387.1|1404622_1405144_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	1.8e-11	33.3
WP_043107936.1|1405221_1407132_-|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	7.9e-129	38.0