CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP009276	Klebsiella variicola strain DX120E plasmid pKV2, complete sequence	0 crisprs	DEDDh	0	0	1
NZ_CP009274	Klebsiella variicola strain DX120E chromosome, complete genome	2 crisprs	csa3,cas3,DEDDh,DinG,cas3HD,WYL	1	1	9
NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	1 crisprs	csa3,cas3	3	3	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

10 : 51047

Klebsiella_phage(86.96%)

portal,terminase,capsid,head,tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023339381.1\|10_1174_+	plasmid-partitioning protein SopA	Q6UAV7	Klebsiella_phage	2.1e-225	98.4
WP_040108014.1\|1176_2142_+	ParB/RepB/Spo0J family plasmid partition protein	Q6UAV8	Klebsiella_phage	8.5e-156	86.9
WP_040108017.1\|2219_3653_-\|tail	tail fiber domain-containing protein	A0A0P0IDN1	Klebsiella_phage	3.4e-84	48.9
WP_158514516.1\|3714_16599_-	DUF1983 domain-containing protein	Q6UAW1	Klebsiella_phage	0.0e+00	48.1
WP_014228919.1\|16661_17273_-\|tail	tail assembly protein	Q6UAW2	Klebsiella_phage	5.3e-71	72.5
WP_021462612.1\|17287_17638_-	hypothetical protein	K7PLP0	Enterobacteria_phage	3.9e-10	38.1
WP_017880253.1\|17669_18380_-	C40 family peptidase	Q6UAW4	Klebsiella_phage	8.5e-137	90.3
WP_040108021.1\|18381_19137_-\|tail	phage minor tail protein L	Q6UAW5	Klebsiella_phage	4.4e-123	79.3
WP_014228916.1\|19133_19472_-\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	8.3e-58	89.3
WP_040108023.1\|19471_22807_-\|tail	phage tail tape measure protein	Q6UAW7	Klebsiella_phage	0.0e+00	88.1
WP_014228914.1\|23039_23405_-\|tail	phage tail protein	Q6UAW8	Klebsiella_phage	1.6e-51	89.3
WP_014228913.1\|23461_23923_-\|tail	major tail shaft subunit	Q6UAX0	Klebsiella_phage	7.8e-67	83.7
WP_021462608.1\|23954_24356_-	hypothetical protein	Q6UAX1	Klebsiella_phage	1.1e-61	93.2
WP_032432816.1\|24352_24742_-	hypothetical protein	Q6UAX2	Klebsiella_phage	9.6e-58	86.0
WP_014228910.1\|24722_25061_-\|head,tail	head-tail adaptor protein	Q6UAX3	Klebsiella_phage	5.6e-54	91.1
WP_020317538.1\|25057_25375_-\|head,tail	phage gp6-like head-tail connector protein	Q6UAX4	Klebsiella_phage	1.5e-45	89.8
WP_040108032.1\|25355_25670_-	hypothetical protein	Q6UAX5	Klebsiella_phage	1.3e-17	79.2
WP_040108035.1\|25728_27015_-\|capsid	phage major capsid protein	Q6UAX6	Klebsiella_phage	7.7e-205	84.6
WP_040108038.1\|27092_28013_-	S49 family peptidase	Q6UAX7	Klebsiella_phage	2.1e-148	87.9
WP_040108041.1\|28049_29309_-\|portal	phage portal protein	Q6UAX8	Klebsiella_phage	3.6e-223	90.0
WP_040108048.1\|29481_31191_-\|terminase	terminase large subunit	Q6UAY0	Klebsiella_phage	0.0e+00	94.9
WP_032408957.1\|31225_31660_-\|terminase	terminase	Q6UAY1	Klebsiella_phage	2.4e-73	95.8
WP_077254208.1\|32162_32594_-	hypothetical protein	Q6UAS0	Klebsiella_phage	2.6e-40	60.6
WP_023339407.1\|32590_32875_-	hypothetical protein	Q6UAS1	Klebsiella_phage	2.4e-05	37.5
WP_032414214.1\|32871_33234_-	HNH endonuclease	Q6UAS2	Klebsiella_phage	7.8e-62	92.5
WP_052251518.1\|33217_34489_-	hypothetical protein	Q6UAS3	Klebsiella_phage	1.2e-35	37.4
WP_032408961.1\|34729_35029_-	DUF4406 domain-containing protein	Q6UAS4	Klebsiella_phage	3.0e-51	96.0
WP_117037470.1\|35140_35335_-	hypothetical protein	Q6UAS6	Klebsiella_phage	1.5e-19	89.5
WP_040108053.1\|35282_35759_-	hypothetical protein	Q6UAS7	Klebsiella_phage	3.9e-61	79.1
WP_040108055.1\|35775_36267_-	hypothetical protein	Q6UAS8	Klebsiella_phage	3.2e-82	90.2
WP_023339388.1\|36263_36575_-	hypothetical protein	Q6UAS9	Klebsiella_phage	6.3e-44	89.1
WP_023339389.1\|36633_37695_-	site-specific DNA-methyltransferase	Q6UAT0	Klebsiella_phage	1.6e-171	93.2
WP_032408967.1\|38012_38240_-	hypothetical protein	Q6UAT1	Klebsiella_phage	1.6e-28	84.0
WP_023339391.1\|38251_38473_-	hypothetical protein	O64358	Escherichia_phage	3.0e-32	90.4
WP_023339392.1\|38643_38952_+	type II toxin-antitoxin system RelE/ParE family toxin	Q6UAT3	Klebsiella_phage	3.9e-46	94.2
WP_023339393.1\|38951_39239_+	helix-turn-helix transcriptional regulator	Q6UAT4	Klebsiella_phage	1.7e-43	96.8
WP_023339395.1\|39590_39818_-	hypothetical protein	O64355	Escherichia_phage	2.8e-25	80.3
WP_032408968.1\|39838_40165_-	hypothetical protein	Q6UAT7	Klebsiella_phage	3.9e-52	94.4
WP_023339397.1\|40157_40403_-	hypothetical protein	G8C7U9	Escherichia_phage	5.1e-25	83.1
WP_040108063.1\|41003_41612_-	3'-5' exonuclease	Q6UAU3	Klebsiella_phage	2.5e-97	88.0
WP_032408971.1\|42023_42761_-	phage antitermination Q family protein	Q6UAU4	Klebsiella_phage	2.2e-119	84.5
WP_032408972.1\|42750_42960_-	hypothetical protein	Q6UAU5	Klebsiella_phage	7.7e-30	92.8
WP_032413541.1\|43040_43649_+	XRE family transcriptional regulator	Q6UAU6	Klebsiella_phage	2.8e-104	92.1
WP_040108069.1\|43900_47905_+	origin of replication-binding family protein	A0A2I6TD01	Escherichia_phage	0.0e+00	81.3
WP_040108071.1\|47897_48194_+	hypothetical protein	NA	NA	NA	NA
WP_040108074.1\|48190_48541_+	hypothetical protein	O64343	Escherichia_phage	3.3e-49	76.7
WP_077268490.1\|49220_50354_-	hypothetical protein	NA	NA	NA	NA
WP_032413547.1\|50882_51047_+	host cell division inhibitor Icd-like protein	Q6UAV3	Klebsiella_phage	2.8e-19	96.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP009274

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP009274_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009274_1

4008526-4008634

Orphan

Consensus_repeat	Method
AGGGAGAGGGAGCACACCCTAAAAAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009274_1

>merge|NZ_CP009274|1|4008526-4008634|CRISPRCasFinder
AGGGAGAGGGAGCACACCCTAAAAAAGGCCATTGTCATTGCCTTTTTGCGTTTACCTTGCCCTCACCCCAACCCTCTCCCACAGGGAGAGGGAGCAAACCCTAAAAAAG

>NZ_CP009274|1|1|4008526-4008634|CRISPRCasFinder
AGGGAGAGGGAGCACACCCTAAAAAAG	GCCATTGTCATTGCCTTTTTGCGTTTACCTTGCCCTCACCCCAACCCTCTCCCAC
AGGGAGAGGGAGCAAACCCTAAAAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009274.2\|WP_008805596.1\|4010130_4011195_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380528
NZ_CP009274.2\|WP_032734958.1\|4008786_4010028_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227601
NZ_CP009274.2\|WP_039102954.1\|4015022_4015766_+\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|235500
NZ_CP009274.2\|WP_039102955.1\|4002525_4003335_+\|inositol-monophosphatase	unknown	unknown	gnl\|CDD\|223559
NZ_CP009274.2\|WP_012542475.1\|3998837_4000073_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377939
NZ_CP009274.2\|WP_012068431.1\|4015949_4016252_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|224937
NZ_CP009274.2\|WP_008805591.1\|4016226_4016631_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP009274.2\|WP_002893903.1\|4016627_4016825_-\|YbdD/YjiX-family-protein	unknown	unknown	gnl\|CDD\|225434
NZ_CP009274.2\|WP_012542481.1\|4013876_4014965_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|182570
NZ_CP009274.2\|WP_008805590.1\|4016917_4019023_-\|carbon-starvation-protein-CstA	unknown	unknown	gnl\|CDD\|184976
NZ_CP009274.2\|WP_016160472.1\|4007289_4008489_+\|S-methyl-5-thioribose-kinase	unknown	unknown	gnl\|CDD\|236561
NZ_CP009274.2\|WP_012542480.1\|4012210_4013713_-\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP009274.2\|WP_008805607.1\|3996518_3997127_-\|methylthioribulose-1-phosphate-dehydratase	unknown	unknown	gnl\|CDD\|236415
NZ_CP009274.2\|WP_008805604.1\|4000069_4001308_+\|cytosine-deaminase	unknown	unknown	gnl\|CDD\|181713
NZ_CP009274.2\|WP_012968720.1\|4011215_4012214_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP009274.2\|WP_008805601.1\|4003445_4004804_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340870
NZ_CP009274.2\|WP_012968717.1\|4006159_4007188_-\|S-methyl-5-thioribose-1-phosphate-isomerase	unknown	unknown	gnl\|CDD\|273112
NZ_CP009274.2\|WP_023339778.1\|3997578_3998841_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|236821
NZ_CP009274.2\|WP_162493334.1\|4001453_4002404_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380501
NZ_CP009274.2\|WP_008805600.1\|4004829_4006098_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366031

Protein	Function_ID	Function_description	E-value
NZ_CP009274.2\|WP_008805596.1\|4010130_4011195_-\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380528	cd06305, PBP1_methylthioribose_binding-like, similar to methylthioribose-binding protein of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily. Proteins similar to methylthioribose-binding protein of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. The sugar-binding domain of the periplasmic proteins in this group is also homologous to the ligand-binding domain of eukaryotic receptors such as metabotropic glutamate receptor (mGluR), DNA-binding transcriptional repressors such as LacI and GalR.	4.03307e-122
NZ_CP009274.2\|WP_032734958.1\|4008786_4010028_-\|hypothetical-protein	gnl\|CDD\|227601	COG5276, COG5276, Uncharacterized conserved protein [Function unknown].	4.78831e-149
NZ_CP009274.2\|WP_039102954.1\|4015022_4015766_+\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	1.05388e-87
NZ_CP009274.2\|WP_039102955.1\|4002525_4003335_+\|inositol-monophosphatase	gnl\|CDD\|223559	COG0483, SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism].	5.36364e-72
NZ_CP009274.2\|WP_012542475.1\|3998837_4000073_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	1.78324e-33
NZ_CP009274.2\|WP_012068431.1\|4015949_4016252_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|224937	COG2026, RelE, Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning].	9.15731e-08
NZ_CP009274.2\|WP_008805591.1\|4016226_4016631_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.5247e-10
NZ_CP009274.2\|WP_002893903.1\|4016627_4016825_-\|YbdD/YjiX-family-protein	gnl\|CDD\|225434	COG2879, COG2879, Uncharacterized small protein [Function unknown].	1.33159e-37
NZ_CP009274.2\|WP_012542481.1\|4013876_4014965_+\|oxidoreductase	gnl\|CDD\|182570	PRK10586, PRK10586, putative oxidoreductase; Provisional.	0
NZ_CP009274.2\|WP_008805590.1\|4016917_4019023_-\|carbon-starvation-protein-CstA	gnl\|CDD\|184976	PRK15015, PRK15015, carbon starvation protein CstA.	0
NZ_CP009274.2\|WP_016160472.1\|4007289_4008489_+\|S-methyl-5-thioribose-kinase	gnl\|CDD\|236561	PRK09550, mtnK, methylthioribose kinase; Reviewed.	0
NZ_CP009274.2\|WP_012542480.1\|4012210_4013713_-\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP009274.2\|WP_008805607.1\|3996518_3997127_-\|methylthioribulose-1-phosphate-dehydratase	gnl\|CDD\|236415	PRK09220, PRK09220, methylthioribulose 1-phosphate dehydratase.	1.57474e-138
NZ_CP009274.2\|WP_008805604.1\|4000069_4001308_+\|cytosine-deaminase	gnl\|CDD\|181713	PRK09230, PRK09230, cytosine deaminase; Provisional.	0
NZ_CP009274.2\|WP_012968720.1\|4011215_4012214_-\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	3.65981e-69
NZ_CP009274.2\|WP_008805601.1\|4003445_4004804_+\|MFS-transporter	gnl\|CDD\|340870	cd17312, MFS_OPA_SLC37, Organophosphate:Pi antiporter/Solute Carrier family 37 of the Major Facilitator Superfamily of transporters. Organophosphate:Pi antiporters (OPA) are integral membrane proteins responsible for the transport of specific organophosphates or sugar phosphates across biological membranes with the simultaneous translocation of inorganic phosphate into the opposite direction. The OPA family is also called solute carrier family 37 (SLC37) in vertebrates. Members include glucose-6-phosphate (Glc6P) transporter (also called translocase or exchanger), glycerol-3-phosphate permease, 2-phosphonopropionate transporter, phosphoglycerate transporter, as well as membrane sensor protein UhpC from Escherichia coli. UhpC is both a sensor and a transport protein; it recognizes external Glc6P and induces transport by UhpT, and it can also transport Glc6P. Vertebrates contain four SLC37 or sugar-phosphate exchange (SPX) proteins: SLC37A1 (SPX1), SLC37A2 (SPX2), SLC37A3 (SPX3), and SLC37AA4 (SPX4). The OPA/SLC37 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.48585e-128
NZ_CP009274.2\|WP_012968717.1\|4006159_4007188_-\|S-methyl-5-thioribose-1-phosphate-isomerase	gnl\|CDD\|273112	TIGR00512, methylthioribose-1-phosphate_isomerase_predicted, S-methyl-5-thioribose-1-phosphate isomerase. The delineation of this family was based in part on a discussion and neighbor-joining phylogenetic study, by Kyrpides and Woese, of archaeal and other proteins homologous to the alpha, beta, and delta subunits of eukaryotic initiation factor 2B (eIF-2B), a five-subunit molecule that catalyzes GTP recycling for eIF-2. This clade is now recognized to include the methionine salvage pathway enzyme MtnA. [Amino acid biosynthesis, Aspartate family].	2.37599e-150
NZ_CP009274.2\|WP_023339778.1\|3997578_3998841_+\|cytosine-permease	gnl\|CDD\|236821	PRK11017, codB, cytosine permease; Provisional.	0
NZ_CP009274.2\|WP_162493334.1\|4001453_4002404_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380501	cd06278, PBP1_LacI-like, ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	4.4627e-95
NZ_CP009274.2\|WP_008805600.1\|4004829_4006098_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366031	pfam00328, His_Phos_2, Histidine phosphatase superfamily (branch 2). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches.The smaller branch 2 contains predominantly eukaryotic proteins. The catalytic functions in members include phytase, glucose-1-phosphatase and multiple inositol polyphosphate phosphatase. The in vivo roles of the mammalian acid phosphatases in branch 2 are not fully understood, although activity against lysophosphatidic acid and tyrosine-phosphorylated proteins has been demonstrated.	3.61435e-59

>NZ_CP009274.2|WP_016160472.1|4007289_4008489_+|S-methyl-5-thioribose-kinase
MSQYHTFTAHDAVAYAQQFAGIDNPSELVSAQEVGDGNLNLVFKVFDRQGVSRAIVKQALPYVRCVGESWPLTLDRARLEAQTLVAHYQHSPQHTVKIHHFDPELAVMVMEDLSDHRIWRGELIANVYYPQAARQLGDYLAQVLFHTSDFYLHPHEKKAQVAQFSNPAMCEITEDLFFNDPYQIHERNNYPAELEADVAVLRDDAQLKLAVAALKHRFFAHAEALLHGDIHSGSIFVAEGSLKAIDAEFGYFGPIGFDIGTAIGNLLLNYCGLPGQLGIRDAAAAREQRLNDIHQLWTTFAERFQALAAEKTRDAALAYPGYASAFLKKVWADAVGFCGSELIRRSVGLSHVADIDTIQDDAMRHECLRHAITLGKALIVLAERIDSVDELLARVRQYS
>NZ_CP009274.2|WP_012968717.1|4006159_4007188_-|S-methyl-5-thioribose-1-phosphate-isomerase
MQTLQTTSLRVSENQLFILDQQALPQEKRWLAADNVALLVDHIHALRVRGAPLIGLSASLLLALLAQRGLNRDALQQALETLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLVEEDKQLCDRIAEAGSALVKPGSRLLTHCNTGGLATAGVGTALGVIALAHRQGKVANVWVDETRPLLQGGRLTAWELGELGVPYQLITDSMAASLMAQGQVDAVWVGADRIAANGDVANKIGTYSLAVLAHYHQIPFYVAAPQTTLDRHCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPTGAAVYNPAFDVTPAGLVSGWVLDSGVVTPAQVAAGAFAPDNG
>NZ_CP009274.2|WP_008805600.1|4004829_4006098_+|histidine-phosphatase-family-protein
MMPARHQGLLRLFIACALPLLALQSAAAADWQLEKVVELSRHGIRPPTAGNREAIEAATGRPWTEWTTHDGELTGHGYAAVVNKGREEGQHYRQLGLLQAGCPTAESIYVRASPLQRTRATAQALVDGAFPGCGVAIHYVSGDADPLFQTDKFAATQTDPARQLAAVKEKAGDLAQRRQALAPAIQLLQQAVCQADKPCPIFDTPWQVEQSKSGKTTISGLSVMANMVETLRLGWSENLPLSQLAWGKITQARQITALLPLLTENYDLSNDVLYTAQKRGSVLLNAMLDGVKPEANPNVRWLLLVAHDTNIAMVRTLMNFSWQLPGYSRGNIPPGSSLVLERWRNAKSGERYLRVYFQAQGLDDLRRLQTPDAQHPMLRQEWRQPGCRQTDVGTLCPFQAAITALGQRIDRSSAPAVAMVLP
>NZ_CP009274.2|WP_008805601.1|4003445_4004804_+|MFS-transporter
MSGIIAFFRASPPKAGAAFDEQRFRRVRWQTFIAMTLAYVTFYVCRLSFTVAKSALVDLGITPTELGMIGSTLFFSYAIGKLVNGFIADHANVVRYMSLGLLLSAGMNLMMGMTTNALLLAIFWGINGWAQSMGVGPCAVSLARWYGVKERGTFYGIWSTAHNIGEAVTYMVIAAVIAGFGWQMGYLSTAALGAAGVVLLVLFMHDSPQSSGFPSINVIRDEPQEEAEARGSVFKNQLLALRNPALWTLALASAFMYIDRYAVNSWGIFFLEQDKAYSTLEASGIIGVNAIAGIAGTIIAGMLSDRFFPRNRSVMAGFISLLNTAGFALMLWSPHNYYTDILAMIIFGATIGALTCFLGGLIAVDISSRKAAGAALGTIGIASYAGAGLGEFLTGIIIDKTAILENGKTLYDFSTLALFWVGTGLGSALLCFTTAAIVARRHAVERQTSFSS
>NZ_CP009274.2|WP_039102955.1|4002525_4003335_+|inositol-monophosphatase
MQSQESEALQARYRLACELAKAGAELAFEYYQQREALTVDHKGDDLQDVVSVADKRVEAFVKQRIQSAFPQDGFLGEESGTRLPDARILWVVDPIDGTSCFLNGLHTWCLSLAIVADGEPVIGVVYDPNHRELFHALRGHGAWLNDAPIRPHPATTVKEGVMGVGTSHRVTPADFLPFLQALLSDGGMFIRNGSGALMSAWAAAGRLIGYYEPHMNPWDALPGLVLMREAGGASNDFLAQEGIQRGNPLLLASQTLYPQLKKMITQPLH
>NZ_CP009274.2|WP_162493334.1|4001453_4002404_+|substrate-binding-domain-containing-protein
MARLAGVSRSAVSRTFTPGASVSEKTRQKVLSAAEALGYQVNIIARTMITGSSNFIGIVTAGFDNPFRSKLLAPLVHQLALNGFMPLLMNADDPQQLAPSLKQLLSYHVAGVIITSGAPPLSLAEEYLARKIPVTLINRHADLAGCDRVCSDNAQGAKLVADLFSRRGWQQVGFIGENRENFSTRQRYEAFIARTSGMAVSSRFCDGGGYQAGYQAARELVAENPGVQALFCATDMLALGALDGLRDAPAPLPAIVGFDDIPQADWQPYQLTTVQQNTALLAHHAVDLLMTRIARFSLPSRHREVPVKLIIRNSAK
>NZ_CP009274.2|WP_008805604.1|4000069_4001308_+|cytosine-deaminase
MKIINARLRRQEALFTLDLQDGMIHRISAQAAMQSADAGDIDAQGRLAIPPFVEPHIHLDATLTAGEPEWNRSGTLFEGITRWSQRKASITPEDTRQRALKTIGMLRDFGVQHVRTHVDVTDPSLAALKALLAVKQEAADLIDLQIVAFPQEGIESYPDGRGLMTRAIEMGADVVGGIPHYENTRDKGVSSVMFLMDLAQRYGRLVDVHCDEIDDPQSRFLEVLAEEARVRGMGAQVTASHTCAMGSYDNAYCSKLFRLLKASGINFISCPTESIHLQGRFDSWPKRRGVTRVAELDRAGINVCFAQDSIQDPWYPLGNGNILRILDAGLHICHMLGYDDLQRCLDFVTDNSARALCLGDNYGLAEGRPANLLILDAENDYEAVRRQARVLTSIRHGKVILQREVEHIRYPA
>NZ_CP009274.2|WP_012542475.1|3998837_4000073_+|PucR-family-transcriptional-regulator
MSLTVSELLALEGLSALRLRAGKQGLQRAVRWYYVAENEHIAEWIMGGELVFITGINHPRDEANLIQLLMEGKQRGIAGMVILTGEAYIHAIPATLIALADELGIPLIEQPYLLKMVIVTERIGTALVRSENALQSQRDILMQLVTGDYPDLQMLHQRALHQQLDFTRPLRLAALRLEGLSRLFRQFPPEQAEAWLLQAHRSVRQQLQQQLNQQGNPFPLLERSNMFLFLLPDEEGEGFQQKKWLQQWLQALADGEEGLSLLCGLSAPVRQLQGYPRALSQARQALDLCDTLRPTQRISDYQQLGFIKLLSAVSDPALLNDFMHDTLGCLIEPGRKAPWLLLETLETLLQENGNVVRAADRLGLHRNTLHQRIQRIEKLTGYPVSHPQFHLNASVALVIWRLSQNHLQDPP
>NZ_CP009274.2|WP_023339778.1|3997578_3998841_+|cytosine-permease
MSNSNDFPLVEAPAAGRKGVFSIAMVLFSFTFFTGTMFAGGKLGVSFSIVNLLWIAVIGNALLALYAASLGWIAARSGLNTVLMGRFCFGEIGSKLADFILGFAELGWYAWGTATVAISLVKILALPEALTQPLMVLFGILFCVTALVGYKGLDALSRLSVPLMFVLLMVSMYLALHHAGGWQAMTHIAPSDTMTWSAAITMVFGTFASGATQATNWTRLANSSRTAILASMGSFLIGNGLMIVAGAWCAIVYQQADIVEVLILQGLSVAAVIMLCLNLLTIQGPTIYNVSAAACHLLRSERRRTLTIAAAGVGIVLAIGGMYEMLIPFLVLLGSIIPPIGGVILADYWFARGGRYPLLQNARLPRFNWLGLGAYAAGAVVAYLSPWIAPLVGITVSALVYIVLSLLSKRQPAAVAEQEP
>NZ_CP009274.2|WP_008805607.1|3996518_3997127_-|methylthioribulose-1-phosphate-dehydratase
MWQERLAQLVTTCHWIGAKGWAPATGGNMSVRQDDTWCWLSESGRDKGSLTTEDFLQVEIATNQAPSGRKPSAETGLHTLVYRLFPEANVVLHVHTVNATVLSRIEKSDTLALQGYEMQKTLSGQHSHLDTVPVAIFDNDQDIDALAARIADYAQTRPLRYGFLLRGHGLTCWGKDIQEARRQLEGLEFLFECELMRRRYEP
>NZ_CP009274.2|WP_032734958.1|4008786_4010028_-|hypothetical-protein
MSVLPSPEYSRNMRLIGHSDQGGRPDGVQLMVHRGFAYIGHMVSQGFSVVDVRDPTRPTTVNYIAAPPGTWNVHLQAHDDLLLVINARDLFADARFADEKVYYTRSVGDTVSDVQDKGWSAGLRIFDISTPAQPREISFLSLNGIGIHRIWYVGGRWAYVSALIDGFTDYIFLTIDLADPRKPEVAGRWWLPGMHQAGGETPDWPQGKRYALHHAIIAGDTAYGSWRDGGLTLLDVKDRTQPTLISHRNWSPPFGGGTHTALPLPDRDLLVVLDEAVLDNQEDGEKLIWLFDIREPANPVSISTFPQPDEIDYVAKGAHFGPHNLHENRPGSFVSSTLIFATYQNAGVRAYDISNPYRPLETGALVPAAPKTMMDTRPGRPQVIQSCDVFVDAQGIIYSTDYNGGLSVIEYLG
>NZ_CP009274.2|WP_008805596.1|4010130_4011195_-|sugar-ABC-transporter-substrate-binding-protein
MKKIALSLMTLGLLQSTAALATAPTPVPAAIAEHSGPIRIAVIRNLGSDDNTTQFVSGALQEGKKLGFKISTFLSNGDDAKFQDFVNQAISQKYDGIILSQGRDPYSTALVKKAVDAGIKVAVFDTAVSGEIPGVTVSQQDDASLTELSFGQLVKDFNGKANIVKLWVAGFPPMERRQAAYQTLLKQNPGIKELESIGAVSSDVQGDTANKVGAILAKYPKGKIDAIWGTWDAFSQGAYKALKENGRTEIKLYSIDISNQDLQLMREAGSPWKVSVAVDPKLIGATNVRLIANKIAGEPTPATYDFKAAAIPQALLAAQPGAVNVASLGKIIPGWGQTEDFIAPWFATLEAKNK
>NZ_CP009274.2|WP_012968720.1|4011215_4012214_-|ABC-transporter-permease
MSKALAVNATVSGRQRFFDFLYKWGMLLTVVLLVAVFGLASDNFLDPFNIINILRSIAIVTVIAIGVSISLTIGGFDLSVGSTASLANALVISLFVWHGLGTTEAILITLALCTLVGLFNAFLIVVLRIPDMLATLASLFVIQGVAMTYSYGGSITENMVLPSGEMAEGTIPAGFGALGQVPTIVIIMLVVTLVAQLALSFTTHGRRMYAIGGNPEAARLSGLRITRYKVAAYVIASLLAGLGGILLASRIGSSQVNAGGGYLMDAVAAAWIGFSLAGSGKPNALGTLVGAVILGVLSNGLVMLSVPYYAMDIIKGLVLAGALALTYFQRRT
>NZ_CP009274.2|WP_012542480.1|4012210_4013713_-|sugar-ABC-transporter-ATP-binding-protein
MSANRLEMHNISLAFSGFQALNKVDFTLHGGSVHALTGANGAGKSTLMAVLCGTHAHYQGEVTINDQPVTIRSPRDAKQLGIHLVQQEVDVALVPGLSIAENIMLDRLAEPGMAFRWSRVRQLAREALAQLDVALDVRRSIDSCTLAEKQQILLARALSHHCRFLILDEPTAPLDQHESERLFAVVRRLQQQGIGVVFISHRIHELKAICDTLTVLRDGRLIESGPMAPLSGEQIVEKMLGHELSDIFPPPRPPHGEEVLLQIDGLHDEALLQDISLRLRKGEILGIAGLAGAGKTELCKALFGASKSRVQRGELNGQPWRPRDPADSVGRGLALVPEERRKEGIFIEEPIAMNLAVSADNSFSRWSLFGHRQAWRWAEEVIARLGVRATGPGQMLRRLSGGNQQKVAIGKWLRSHANVLIFDEPTKGVDVKAKTDLFMLIDGLAREGKGVIYASGEFAELVGLCDRICVLWDGRIVAEIPGAEAREETLLYYSTGGAAA
>NZ_CP009274.2|WP_012542481.1|4013876_4014965_+|oxidoreductase
MSNSDIRVVPGPANYFSHPGSLERLSDFFSADQLSRAVWVYGERALAGAEPFLPAAFHLPEAKKIRFTGHCSERDVAALVQASGDDRAVVIGVGGGALLDSAKVLARRLGVPLVAIPTIAATCAAWTPLSVWYSDAGQALNFEIFDDANFLVLVEPRIILNAPAEYLLAGIGDTLAKWYEAVVLAPQPEALPLTVRLGINGALAIRDVLLASSETALADQRRGDLTQAFRDVVEAIIAGGGMVGGLGERYTRVAAAHAVHNGLTVLPQTDKFLHGTKVAYGILVQSALLAQDDVLAQLVQAYQRFNLPTTLAALEVDINNRTELDRVIAHTLRPGESIHYLPVTLTPEVLRAAFEKVEYFSR
>NZ_CP009274.2|WP_039102954.1|4015022_4015766_+|3-oxoacyl-ACP-reductase-FabG
MQIDLTGKKALVTGASRGLGRAIALSLARAGADVVITYEKSADKAQAVADEIKALGRHGEAVQADSASAQAIQEAVTHAARSLGGLDILVNNAGITRGGPLESMTLADIDALINVNIRGVVIATQEALVHMADGGRIINIGSCLANRVAMPGIAVYAMTKSALNALTRGLARDLGPRGITVNLVHPGPTNSDMNPEDGEQAEAQRQMIAVGHYGQPEDIAAAVTFLASPAAGQISGTGLDVDGGLNA
>NZ_CP009274.2|WP_012068431.1|4015949_4016252_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKIVWSKTADKPFSKIDNRYKSRIKSRLEKMDDKASSISDIKKLSSPENHYRLRLGDYRVIYTFGDPPGDTCYVVAVKRRTTTTYLHEEDTEYDYSVHQG
>NZ_CP009274.2|WP_008805591.1|4016226_4016631_+|helix-turn-helix-transcriptional-regulator
MTIQYIKDEEGKDQYVVIPYSDYFRMRLALLEYDDEDESDWEDIPYESDIYDNVMLPGEVCDVMHKENVSLQAAWRILRGLSQQEVAAKLGISQSAVSQLEALDSRPQKRTREKLAAIYGCTQEQISLYLPKEG
>NZ_CP009274.2|WP_002893903.1|4016627_4016825_-|YbdD/YjiX-family-protein
MFDTLSKAGKYLGQAAKMMIGVPDYDNYVEHMRITHPDQTPMTYEEFFRERQDARYGGKGGAKCC
>NZ_CP009274.2|WP_008805590.1|4016917_4019023_-|carbon-starvation-protein-CstA
MNNSGKYLIWTLLSVIGAFALGYIALNRGEQINALWIVVAAVCVYLIAYRFYGLYIAKTVLGVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPLVGPVLAAQMGYLPGMIWILAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAGVLALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLAIFMGIYIRYLRPGRIGEVSVIGLVMLVFAIISGGWVAESPTWAPWFDYTGVQLTWILVGYGFVAAVLPVWLLLAPRDYLSTFLKIGTIVGLAIGILIMRPTLTMPALTKFVDGTGPVWSGNLFPFLFITIACGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVAACIIDPGVYFAMNSPMAVLAPAGTTDVVASAAQVVSGWGFSITPDTLHQIASEVGEQSIISRAGGAPTLAVGMAYILHGSLGGLMDVSFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVISPGLKKTSSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLCAVVLFKMKRQRYAWVALLPTSWLLICTLTAGWQKSFSPDTKVGFLAIANKFQAMIDSGNIPPQYTESQLAQLVFNNRLDAGLTIFFMIVVVVLALFSIKTALAALKEDKPTAKETPYQAMPADAQTITAQAKRAH

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Crispr_ID: NZ_CP009274_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009274_2

5104141-5104265

Orphan

Consensus_repeat	Method
GTAGCCCCGGTAAGCGGTAGCGCTACCGGGGATTTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009274_2

>merge|NZ_CP009274|2|5104141-5104265|CRISPRCasFinder
GTAGCCCCGGTAAGCGGTAGCGCTACCGGGGATTTTCCCCGGAGGCGGCGCATTGCGCCTTCTCCGGGCTACCAAATCGCACAACGCTGTAGCCCCGGTAAGCGGTAGCGATACCGGGGATTTTC

>NZ_CP009274|2|2|5104141-5104265|CRISPRCasFinder
GTAGCCCCGGTAAGCGGTAGCGCTACCGGGGATTTTC	CCCGGAGGCGGCGCATTGCGCCTTCTCCGGGCTACCAAATCGCACAACGCT
GTAGCCCCGGTAAGCGGTAGCGATACCGGGGATTTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009274.2\|WP_074442684.1\|5115977_5116535_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_CP009274.2\|WP_008807262.1\|5106829_5108788_+\|acetate--CoA-ligase	unknown	unknown	gnl\|CDD\|234677
NZ_CP009274.2\|WP_023296901.1\|5110989_5112087_-\|type-1-fimbrial-protein	unknown	unknown	gnl\|CDD\|237935
NZ_CP009274.2\|WP_049163826.1\|5112106_5112658_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185193
NZ_CP009274.2\|WP_008807253.1\|5094507_5096028_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP009274.2\|WP_077598880.1\|5101969_5104117_+\|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|130652
NZ_CP009274.2\|WP_039102728.1\|5112694_5115274_-\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|225729
NZ_CP009274.2\|WP_039102727.1\|5115227_5115917_-\|fimbrial-assembly-chaperone	unknown	unknown	gnl\|CDD\|237936
NZ_CP009274.2\|WP_008807258.1\|5100968_5101697_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP009274.2\|WP_004206363.1\|5096024_5097023_+\|ribose-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226633
NZ_CP009274.2\|WP_016160120.1\|5104382_5105069_+\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|276807
NZ_CP009274.2\|WP_039102729.1\|5100124_5100883_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371541
NZ_CP009274.2\|WP_024623073.1\|5109282_5110935_+\|cation/acetate-symporter-ActP	unknown	unknown	gnl\|CDD\|236495
NZ_CP009274.2\|WP_012543161.1\|5105103_5106417_-\|glutamate/aspartate:proton-symporter-GltP	unknown	unknown	gnl\|CDD\|183075
NZ_CP009274.2\|WP_004177812.1\|5108971_5109283_+\|DUF485-domain-containing-protein	unknown	unknown	gnl\|CDD\|225704
NZ_CP009274.2\|WP_012543155.1\|5097053_5097995_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380544
NZ_CP009274.2\|WP_039102730.1\|5098069_5099077_+\|carbohydrate-kinase-family-protein	unknown	unknown	gnl\|CDD\|223598
NZ_CP009274.2\|WP_039102732.1\|5092042_5094328_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_CP009274.2\|WP_012543151.1\|5091618_5091972_-\|membrane-protein	unknown	unknown	gnl\|CDD\|237171
NZ_CP009274.2\|WP_012969143.1\|5099201_5100119_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	unknown	unknown	gnl\|CDD\|378065

Protein	Function_ID	Function_description	E-value
NZ_CP009274.2\|WP_074442684.1\|5115977_5116535_-\|fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	3.16425e-18
NZ_CP009274.2\|WP_008807262.1\|5106829_5108788_+\|acetate--CoA-ligase	gnl\|CDD\|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0
NZ_CP009274.2\|WP_023296901.1\|5110989_5112087_-\|type-1-fimbrial-protein	gnl\|CDD\|237935	PRK15292, PRK15292, type 1 fimbrial protein.	4.04384e-169
NZ_CP009274.2\|WP_049163826.1\|5112106_5112658_-\|fimbrial-protein	gnl\|CDD\|185193	PRK15293, PRK15293, fimbrial protein SthD.	1.65976e-18
NZ_CP009274.2\|WP_008807253.1\|5094507_5096028_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP009274.2\|WP_077598880.1\|5101969_5104117_+\|formate-dehydrogenase-subunit-alpha	gnl\|CDD\|130652	TIGR01591, Formate_dehydrogenase_subunit_alpha, formate dehydrogenase, alpha subunit, archaeal-type. This model describes a subset of formate dehydrogenase alpha chains found mainly archaea but also in alpha and gamma proteobacteria and a small number of gram positive bacteria. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The enzyme's purpose is to allow growth on formate in some circumstances and, in the case of FdhH in gamma proteobacteria, to pass electrons to hydrogenase (by which process acid is neutralized). This model is well-defined, with only a single fragmentary sequence falling between trusted and noise. The alpha subunit of a version of nitrate reductase is closely related.	0
NZ_CP009274.2\|WP_039102728.1\|5112694_5115274_-\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|225729	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP009274.2\|WP_039102727.1\|5115227_5115917_-\|fimbrial-assembly-chaperone	gnl\|CDD\|237936	PRK15295, PRK15295, fimbrial assembly chaperone.	1.99891e-147
NZ_CP009274.2\|WP_008807258.1\|5100968_5101697_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.30681e-71
NZ_CP009274.2\|WP_004206363.1\|5096024_5097023_+\|ribose-ABC-transporter-permease	gnl\|CDD\|226633	COG4158, COG4158, Predicted ABC-type sugar transport system, permease component [General function prediction only].	1.22458e-170
NZ_CP009274.2\|WP_016160120.1\|5104382_5105069_+\|sel1-repeat-family-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.11274e-16
NZ_CP009274.2\|WP_039102729.1\|5100124_5100883_-\|hypothetical-protein	gnl\|CDD\|371541	pfam11459, AbiEi_3, Transcriptional regulator, AbiEi antitoxin, Type IV TA system. AbiEi_3 is the cognate antitoxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	6.61474e-57
NZ_CP009274.2\|WP_024623073.1\|5109282_5110935_+\|cation/acetate-symporter-ActP	gnl\|CDD\|236495	PRK09395, actP, cation/acetate symporter ActP.	0
NZ_CP009274.2\|WP_012543161.1\|5105103_5106417_-\|glutamate/aspartate:proton-symporter-GltP	gnl\|CDD\|183075	PRK11283, gltP, glutamate/aspartate:proton symporter; Provisional.	0
NZ_CP009274.2\|WP_004177812.1\|5108971_5109283_+\|DUF485-domain-containing-protein	gnl\|CDD\|225704	COG3162, COG3162, Predicted membrane protein [Function unknown].	1.34398e-43
NZ_CP009274.2\|WP_012543155.1\|5097053_5097995_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380544	cd06321, PBP1_ABC_sugar_binding-like, periplasmic sugar-binding domain of uncharacterized ABC-type transport systems. This group includes the periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consist of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	1.71779e-130
NZ_CP009274.2\|WP_039102730.1\|5098069_5099077_+\|carbohydrate-kinase-family-protein	gnl\|CDD\|223598	COG0524, RbsK, Sugar kinases, ribokinase family [Carbohydrate transport and metabolism].	6.89025e-56
NZ_CP009274.2\|WP_039102732.1\|5092042_5094328_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	1.05938e-95
NZ_CP009274.2\|WP_012543151.1\|5091618_5091972_-\|membrane-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0.000812459
NZ_CP009274.2\|WP_012969143.1\|5099201_5100119_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	gnl\|CDD\|378065	pfam08843, AbiEii, Nucleotidyl transferase AbiEii toxin, Type IV TA system. This family was recently identified as belonging to the nucleotidyltransferase superfamily. AbiEii is the cognate toxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	1.24855e-29

>NZ_CP009274.2|WP_077598880.1|5101969_5104117_+|formate-dehydrogenase-subunit-alpha
MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLKGYYGWDFINDTQILTPRLKTPMIRRQRGGKLEAVSWDEALDYVATRLSAIKAKYGPDAIQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNAITEIDNTDLVFIFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIALKNGSNIALLNAIGHVIIEEDLYDKSFVASRSEGFEEYRKIVEGYTPESVEAITGVSAQEIRACARMYASAKSAAILWGMGVTQFYQGVETVRSLTSLAILTGNLGKPSVGVNPVRGQNNVQGACDMGALPDTYPGYQYVKFPENREKFAKAWGVDSLPEHTGYRISELPHRAAHGEVRAAYIMGEDPLQTDAELSAVRKAFDDLELVIVQDIFMTKTASAADVILPSTSWGEHEGVYTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHLCPDFYGATYEKMGELGYVMWPCRDESDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPIDKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTADAERLGIEDEALVWVNSRKGRIITRAQVSDRPNKGAVYMTYQWWIGACNELVSENLSPITKTPEYKYCAVNVERIADQRAAEQYVIDEYNKLKARLRESAMG
>NZ_CP009274.2|WP_008807258.1|5100968_5101697_-|response-regulator-transcription-factor
MKPVILVVDDDIAMGELLSDVLGAHAFEVLVCQTGGDALARVAQRADIALVLLDMILPDTHGLQVLQQLQRTRPELPVVMLSGLGSESDVVVGLEMGADDYIAKPFSSRVVVARVKAVLRRSGALAGETSGVGSGLTFNGWRLDTTRCELYNPQQQAIPLTQGEYGLLLALAQNARRVLNREQLLALTHNESTEVFDRTIDVLIMRLRRKIELNPHQPTLIKTLRGLGYVFSADVTHSDKAA
>NZ_CP009274.2|WP_039102729.1|5100124_5100883_-|hypothetical-protein
MSSKLNWLLQNSAPGDVILQSWLSRHAISPSLAFKYTQSGWLKKRGNGVYARAGREPEWNDALACLQNQLAAPVYVAGLSSLVWQGRSHYLQLKQNQCWLSMENKALLPKWFREFPGVEWIVISGQKLPVLDDKYRVTLDVKGKRLTGSAPELAAYELLSAVPGTLSFNHAAELFQGLVNLNPRKVEYLLSVSQSVQTKRLYLFFASFYEHGWLRRIDSQKIDLGAGKRQIVVNGKFNAQYQITVPERFQKE
>NZ_CP009274.2|WP_012969143.1|5099201_5100119_-|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein
MDIQAPYYRQVALLMQVLPYVAVEREFALKGGTAINLFIRDFPRLSVDIDLAWVPLESRAIALPHIRDALARIAANLQQQAGMNAVLQANRSDEMRVVVTTDSAQIKIEVSPVARGTLYPPQEREVVGAVEDVFGYASLPVVSLPDLYGGKLCAALDRQHPRDFYDVKLLLDAQELNRPIFNGFIAYLLSHNRPLAEVLSPRWKDIAEPFYREFSGMTFETIALEELTAVPYRMIDALKSCFTQQDIDFLLSFKRGEPDWRLAPETRIQDLPAVQWKLRNIHQMPAIKRAESLDKLEKVLAEWRS
>NZ_CP009274.2|WP_039102730.1|5098069_5099077_+|carbohydrate-kinase-family-protein
MERKGIIAAGNMLVDHVHQIRQWPERGWLVEIVHSERATGGAPLNVLLTLAKMHAGLPLQAVGLIGEDNDGDYITAMLDQYHINRQLVQRTSSAPTSMTQVMTDADGQRTFFHSPGANRLLDLPAFEPLDTPLKIFHLGYLLLLESLDLPDEAFGTRSARLLAQMRDRGYEVSLDLVSRKGDPHYRPRVLPALAHLDYLTINELEACEFSGLEIRLPNGEPHVANIARAASALLDAGVRQRVVIHCPEGAWGVSRTEAGRWVPSWRLPPEEIIGSVGAGDAFCAGLLYGSHERWPLTDSLQLAHACARASLQAANAIDGAKTLPELQAFIQLQNG
>NZ_CP009274.2|WP_012543155.1|5097053_5097995_+|ABC-transporter-substrate-binding-protein
MRLKPIVTALCAGALLAASPFASAKELKAIGVTVGDLANPFFVQITKGAELEARKLAGDNVKVTLVSSGYDLGQQVAQIDNFIAAKVDMIILNAADSKGIGPAVKRAKEAGIVVVAVDVAAEGADATITSDNTQAGELACKYISDRLNNKGSVVIINGPPVSAVQNRVEGCETEFKKHPDIKILSSNQNAKGSREGGLEVMTSLLAANPKIDGVFAINDPTAIGADLAAKQAQRSEFFIVGVDGSPDGEEALKRKNSLFVATPAQDPQVMAAKAVEIGYDILQGKPAPTAPVLIPVTMIDKNNVSSYKGWTVK
>NZ_CP009274.2|WP_004206363.1|5096024_5097023_+|ribose-ABC-transporter-permease
MSIPKETSAPVAKSASAKKMLMGDLMQTVGILPILILIVAVFGFIAPNFFTESNLLNITRQASINIVLAAGMTFIILTGGIDLSVGSILGTTAVAAMVVSLIPELALLSIPAALMLGLLLGLFNGALVAFAGLPPFIVTLGTYTALRGAAYLLADGTTVINSDISFEWIGNDYLGPVPWLVVIALAVIAVCWFILRRTTLGVHIYAVGGNMQAARLTGIKVWLVLLFVYGMSGLLSGLGGVMSASRLYSANGNLGVGYELDAIAAVILGGTSFVGGIGTITGTLVGALIIATLNNGMTLMGVSYFWQLVIKGAVIIIAVLIDKYRTRHHQSA
>NZ_CP009274.2|WP_008807253.1|5094507_5096028_+|sugar-ABC-transporter-ATP-binding-protein
MTATPVLEMRHIAKAFGKFYALKGVDLTVWPGEIHALMGENGAGKSTLMKILAGAYTATSGEILIDGKPQTIRGPKDALAAGITLIYQEMQLAPNLTVAENIFLGSELARGGLVQRKAMLSQAQAVIDRLGAQFKASDRVMTLTIAEQQQVEIARALHRQSRILVMDEPTAALSSRETQRLFELILRLRDEGMAIIYISHRMAEVYELSDRVSVLRDGQYVGSLVRDKLNAPELVRMMVGRPLSDLFNKERDIPRGQPRLRVEDLTDGGKVKPSSLVVHAGEIVGLAGLVGAGRSELAQLIFGVRKATGGVIEIDGEPVVIHSPREAIDLGIGFLTENRKEQGLFLELAAQENITMATLERDANWGMLNRRKAQTISDDAIQLLNIRVPHAQVRAGGLSGGNQQKLLISRWVAIGPRILILDEPTRGVDVGAKSEIYRIMNDMARQGVAILMISSELPEVVGMSDRVYVMREGAIAGELQAGDISQESIMTLATGVNDSHLKAGQL
>NZ_CP009274.2|WP_039102732.1|5092042_5094328_-|response-regulator
MTARRHPFFTSARGRLLSFNLLMGVVTLLVSGVAVFGFHHASQLQEQVQRQTLNDMRGSMDLARDTANVATAAVRLSQVVGALEYKSEAERLLATQQALKHSLAQLAAAPLAQQEQARVANIIRRSNALQQSVAEMLERGQRRHLQRNALLSSLYQNQSNLRHLADLNDRGGDKAIDPRRLAEMDRLIVAAIHTVTPRSIVLQLDQLRGDLPAGSADPALAFFLPDVTGELAKLAPLSAQLEESDLTISWYMYHIKALVALLNEDINQYVTRVAEASEQRAAQSHRELRSISMFILLSALLALAITGCAGWYIYRNLGSNLTAISLAMSRLAQGEPNVSVPALQRRDELGELARAFNVFARNTASLEHTTRLLKEKTTQMEIDRIKRQELEEALLHSQKMKAVGQLTGGLAHDFNNLLAVIIGSLELVEPDARDAPRLSRALKAAERGALLTQRLLAFSRKQALHPQAVAMAPLLENLSELMRHSLPATLSLEIEAQSPAWPAWIDVGQLENALINLVMNARDAMAGRDGVIKIRTWNQRVTRSSGQRQDMVALEVIDHGSGMSQAVKARVFEPFFTTKATGSGSGLGLSMVYGFVRQSGGRVALESAPGQGTTVRLQLPRAMTEVETTVAPAEDEPLPAGERLALVLEDEEDVRQTLCEQLHQLGWLTLETPSGEEALQLLEASPDIALLISDLMLPGALSGADVIHTARRRFPALPVLLISGQDLRPAQNPALPEVEWLRKPFTRAQLVQALSAAYARI
>NZ_CP009274.2|WP_012543151.1|5091618_5091972_-|membrane-protein
MKRYATALLFCTLSLTSLAARADIIDDAIGNIQQAINDAYNPGSNRSDDDDRYDDDGRYDDGRYQGSRQQSRDSQRQYDDRQRQLDDRRRQLDERQRQLDQDRRQLESDQRRLDDSY
>NZ_CP009274.2|WP_016160120.1|5104382_5105069_+|sel1-repeat-family-protein
MKYLFLFLLVFTSGAAVATEPGSQYQQQAEAGDRRAQYYLADTWVSSGDYQKAEYWAQKAAAQGDGDALALLAQLKIRNPQQADYPQARQLAEKAVKVGSKSGEIVLARVLVNRQAGPTDVAHAITLLQDAARDSESDAAVDAQMLLGLIYASGVHGPEDDVKASEYFKGSSALSRTGYAEYWAGMMFQQGEKGFIEPNKQKALHWLNVSCLEGFDTGCEEFDRISKG
>NZ_CP009274.2|WP_012543161.1|5105103_5106417_-|glutamate/aspartate:proton-symporter-GltP
MKKTKKVSLAWQILLALVLGILLGSYLHYHAESRDWLISNLLTPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIVLGITLANVFQPGTGIDMSQLAAVDISKYQSTTAEVQSHAHGLMGTILSLVPTNIVASMAKGDMLPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAILFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEITLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTAQ
>NZ_CP009274.2|WP_008807262.1|5106829_5108788_+|acetate--CoA-ligase
MSQIHKHPIPANIAERCLINPEQYKAQYQQSITDPDTFWGEQGKILDWIRPYTRVKNTSFAPGNISIKWYEDGTLNLAANCLDRHLAERGDQTAIIWEGDDASQSKHITYRELHADVCRFANVLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAIHSVIFGGFSPEAVAGRIIDSSSRLVITADEGLRAGRAIPLKKNVDDALKNPNVNSIEHVVVLKRTGGKIDWQEGRDLWWSDLMANASAEHRPVEMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHKVSILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGNEKCPVMDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPVLVDNEGLPLDGATEGNLAIADSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVSHPKIAEAAVVGIPHNIKGQAIYAYVTLNHGEEPTPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSNLGDTSTLADPGVVEKLLEEKQAITMPS
>NZ_CP009274.2|WP_004177812.1|5108971_5109283_+|DUF485-domain-containing-protein
MNEQLCQRIENSAHFRELVASRQRFAAILSVIMLVIYVGFILLIAFAPGWLGTPLHAGTSVTRGIPLGIGVIVISFILTGIYVWRANGEFDRLTKSVLNEVKA
>NZ_CP009274.2|WP_024623073.1|5109282_5110935_+|cation/acetate-symporter-ActP
MKRVLTALAATLLPLGAHAADAITGAVQRQPTNWQAIVMFLIFVALTLYITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDFMSAASFLGISALVYTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRTLSACGSLVVVALYLIAQMVGAGKLIQLLFGLNYHVAVVLVGVLMVLYVLFGGMLATTWVQIIKAVLLLCGASFMAFMVMKHVGFSFNNLFTEAMAVHPKGAAIMSPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPAFKDAAGQLIGGNNMAAVHLADAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATERQELKVSKITVLILGVVAILLGILFENQNIAFMVGLAFSIAASCNFPIILLSMYWSKLTTRGAMVGGWLGLLTAVILMILGPTIWVQILGHEKALFPYEYPALFSIAIAFIGIWVFSATDNSPEGMREREQFRAQFIRSQTGIGIERGQAH
>NZ_CP009274.2|WP_023296901.1|5110989_5112087_-|type-1-fimbrial-protein
MKKLIFLFMLVLCPLYSWAACTGTNYGDVSMTNLPEKILVNAGSYTAGTVLYDSGKITRAQTELINCEGSTYAVFAWSSNNAGALIGDNIYATSVQGIGLRVKVWLNISGEYDGDTDDFSPDSQVHYIGDVNYYLGKPTGLFDYYASTHYTPAYQLQLVATGGAIASNSQLSFSDPVATVSAKDSKATLSISRLHISGTTSIQMIPMGCIVGSNNLSFAMGSINASEFNTATKVGNARQSLTLACEPGTNVSMRVAAAQASGDNPGNTVIALTAEENVATGVGVQLNMDGEALPLNTDISLYTSSRTTVTNSGADASYSYFTNPDSPGGAAAMQTLALSTNYYKTGSAVTAGSANATGVITLTYN
>NZ_CP009274.2|WP_049163826.1|5112106_5112658_-|fimbrial-protein
MNMRDGSTRGILVASLLLLSLPALAYEGSSTVNFNVTGTIEAPSCEVAVEPSNSIDLGTVSSQTFSGNAGSSGASVPVKLVFSSCSADASAVTIAFSGAKFDNTYTSVYKNFRTGSDGASGVGMQLLTLADQQPLGPGDQYLYTFGDRADVHIFNMVARMFSPYGQVKPGIVGFTATFDVAYK
>NZ_CP009274.2|WP_039102728.1|5112694_5115274_-|fimbrial-biogenesis-outer-membrane-usher-protein
MIMVCQGRNIPLSFSSVELLFSTKSICVAIVLCLSTLSSRAEAGEYFNPNLLEVAEEPAASVDLSYFSQDGVPPGTYHLDVYINDKYVSSESLTFQEIGHDAGATASPCLSAEYLNSWLINTTAYPQLFAAGETCARLSAIPGMTFSVSLAQQRIDFTVPQAAMLNRPRDYIPESQWQQGINAGLLNYSVTGQRNAPRHNGATVDSQFVSLQPGVNLGPWRLRNYSTYSHSDNSSRWESVYSYLARDIHTLRSQLVVGNTYTSSGIFDSVSFTGLQLSSDKEMLPDSLHGFAPTIRGIARTTAEVSVYQNGYSIYKTTVAPGAFEINDLYATGSAGDLYVTVKESDGSEQNFVVPFASLAVLQREGQLDYALSSGRTRSGSSDDKEYNFIQSSLAYGATSNFTLYTGFQQAEDKYTNLLLGAGFNLGTIGALSFDGSQSWADVKTSDTASSTRKEQGQSYRVRFSKSFLQTGTSFSVAGYRYSTAGYYSFQDFVDNASTQRDCCTQSGRTKGRFDASLSQTLFGYGSLSLSLVNETYWDSSRMESVGVGYSGSIGRASYFINYSYNRNVQSTDDSGNNRPASDTIVSLTLSIPLGETLSANYTLNHGRHNDTTHSVGLNGSAFEDRSLNWSLQEGYNTQDKSTSGNLSVNYQGAKGDVAGGYGYDHYSNHYNYSLRGGMVAHAGGLTLSRFLGESAALIETPGVSDVRVQGQTNVTTDAAGYAVVPYVRPYHRNSLALDEQQMAGAEVDNVARTVVPTRNAIVKVQYDTRIGYKAMLTLRTRNGVVPFGALVTLDNDRASAARSNIVGDEGQVYLTGLQKKGQLLARWGEKSSEQCTVHYDFSSMALGYDILFYQAECR
>NZ_CP009274.2|WP_039102727.1|5115227_5115917_-|fimbrial-assembly-chaperone
MRYPFFVVGFLLSSSIAQASVVVGGTRLVFDGVKNNAVITVENKDQSSNIVQSWLSVVDAASPAKDAFIITPPLFRLKAGEKGFVRVVRSGKKLPDDRESMFWLNIKGIPATEYVPDKNVVQFAINSKIKLIYRPAALKGNTPESYAEKLQWGKAGDSVTVKNNSPLYMNFSQVSLNGKNISGAWFAAPFSTLKIPVQSTLSATGKKEITWSVINDYGMSGKKYTAIIQ
>NZ_CP009274.2|WP_074442684.1|5115977_5116535_-|fimbrial-protein
MDMGINMKMSKKILAGALIFSACSVLSTVAQADNTITFNGVVSDTTCTATIDGGVTAIDMGTTSVADLKAYTFGAAKNFSFSLADCPTAEDGGNSIARVTFGGVSDTANSDYFKNQATDEPATGVAVALFDEAGKVMKNNEEGSDVDISSGAATIPFTVKMVKSGDTDPTKGTVQTTVTYNVTYY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP009274_2	2.1\|5104178\|51\|NZ_CP009274\|CRISPRCasFinder	5104178-5104228	51	NZ_CP009274.2	4128298-4128348	1	0.98
NZ_CP009274_2	2.1\|5104178\|51\|NZ_CP009274\|CRISPRCasFinder	5104178-5104228	51	NZ_CP009274.2	4519590-4519640	2	0.961
NZ_CP009274_2	2.1\|5104178\|51\|NZ_CP009274\|CRISPRCasFinder	5104178-5104228	51	NZ_CP009274.2	4519677-4519727	2	0.961

1. spacer 2.1|5104178|51|NZ_CP009274|CRISPRCasFinder matches to position: 4128298-4128348, mismatch: 1, identity: 0.98

cccggaggcggcgcattgcgccttctccgggctaccaaatcgcacaacgct	CRISPR spacer
cccggaggcggcgcattgcgccttctccgggctaccaaatcgcacagcgct	Protospacer
**********************************************.****

2. spacer 2.1|5104178|51|NZ_CP009274|CRISPRCasFinder matches to position: 4519590-4519640, mismatch: 2, identity: 0.961

cccggaggcggcgcattgcgccttctccgggctaccaaatcgcacaacgct	CRISPR spacer
cccggaggcggcgcattgcgccttatccgggctaccaaatcgcacagcgct	Protospacer
************************ *********************.****

3. spacer 2.1|5104178|51|NZ_CP009274|CRISPRCasFinder matches to position: 4519677-4519727, mismatch: 2, identity: 0.961

cccggaggcggcgcattgcgccttctccgggctaccaaatcgcacaacgct	CRISPR spacer
cccggaggcggcgcattgcgccttatccgggctaccaaatcgcacagcgct	Protospacer
************************ *********************.****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP009274_2	2.1\|5104178\|51\|NZ_CP009274\|CRISPRCasFinder	5104178-5104228	51	LR134132	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 12	103181-103231	2	0.961
NZ_CP009274_2	2.1\|5104178\|51\|NZ_CP009274\|CRISPRCasFinder	5104178-5104228	51	LR134122	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2	345923-345973	6	0.882
NZ_CP009274_2	2.1\|5104178\|51\|NZ_CP009274\|CRISPRCasFinder	5104178-5104228	51	LR134132	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 12	116956-117006	11	0.784
NZ_CP009274_2	2.1\|5104178\|51\|NZ_CP009274\|CRISPRCasFinder	5104178-5104228	51	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	676412-676462	11	0.784

1. spacer 2.1|5104178|51|NZ_CP009274|CRISPRCasFinder matches to LR134132 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 12) position: , mismatch: 2, identity: 0.961

cccggaggcggcgcattgcgccttctccgggctaccaaatcgcacaacgct	CRISPR spacer
cccggaggcggcgcgttgcgccttctccgggctaccaaatcgcacagcgct	Protospacer
**************.*******************************.****

2. spacer 2.1|5104178|51|NZ_CP009274|CRISPRCasFinder matches to LR134122 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2) position: , mismatch: 6, identity: 0.882

cccggaggcggcgcattgcgccttctccgggctaccaaatcgcacaacgct	CRISPR spacer
cccggaggcggcgcattgcgccttctccgggctaccaaatcgcgcgggacc	Protospacer
*******************************************.*.. .*.

3. spacer 2.1|5104178|51|NZ_CP009274|CRISPRCasFinder matches to LR134132 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 12) position: , mismatch: 11, identity: 0.784

cccggaggcggcgcattgcgccttctccgggctaccaaatcgcacaacgct	CRISPR spacer
tccggaggcggcgcgttgcgccttgtccgggctaccaaagaactgtaggcc	Protospacer
.*************.********* **************  .*   * **.

4. spacer 2.1|5104178|51|NZ_CP009274|CRISPRCasFinder matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 11, identity: 0.784

cccggaggcggcgcattgcgccttctccgggctaccaaatcgcacaacgct	CRISPR spacer
cccggaggcggcgcgttgcgccttctccgggctaccacggcgtaatctgta	Protospacer
**************.********************** . **.*   .*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1645169 : 1652095

Bacillus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008804073.1\|1645169_1646033_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.9e-08	22.9
WP_016161506.1\|1646043_1646817_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-26	37.2
WP_008804075.1\|1647056_1647953_-	lipid kinase YegS	A0A1V0SBJ0	Catovirus	3.6e-15	29.8
WP_008804076.1\|1648195_1649557_-\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.0e-207	94.8
WP_004201558.1\|1649873_1650596_-	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	8.3e-31	33.2
WP_012541063.1\|1650592_1652095_-	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	8.6e-30	28.3

DBSCAN-SWA_2

1694305 : 1706582

Enterobacteria_phage(22.22%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000043542.1\|1694305_1695712_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	4.7e-38	28.7
WP_032736000.1\|1695934_1696999_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.0e-105	55.0
WP_032735999.1\|1697025_1697895_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	7.5e-111	66.7
WP_004206787.1\|1697926_1698817_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	3.7e-28	33.2
WP_023297948.1\|1698831_1699386_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	5.0e-52	58.2
WP_000704907.1\|1699567_1700734_+	UDP-glucose 6-dehydrogenase	M1I798	Paramecium_bursaria_Chlorella_virus	7.0e-112	54.7
WP_004144151.1\|1701156_1701279_-	small membrane protein	NA	NA	NA	NA
WP_071983253.1\|1701415_1701610_-	hypothetical protein	NA	NA	NA	NA
WP_008804104.1\|1701678_1702683_-	NAD-dependent epimerase	E3T4Y8	Cafeteria_roenbergensis_virus	1.2e-30	29.2
WP_039104127.1\|1703760_1705176_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	1.2e-52	30.6
WP_012967600.1\|1705199_1706582_+	phosphomannomutase CpsG	A0A127AWJ1	Bacillus_phage	4.2e-31	25.8

DBSCAN-SWA_3

1813608 : 1851189

Klebsiella_phage(23.68%)

terminase,protease,integrase,portal,tail,holin

attL 1813434:1813493|attR 1856781:1856845

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1813434:1813493	attL	NA	NA	NA	NA
WP_004184758.1\|1813608_1814601_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	4.9e-175	87.2
WP_004184757.1\|1814602_1814830_-	DUF4224 domain-containing protein	Q8HAA9	Salmonella_phage	1.1e-29	78.4
WP_039104070.1\|1815137_1815566_-	hypothetical protein	NA	NA	NA	NA
WP_039104069.1\|1815562_1815943_-	HNH endonuclease	K7P7B7	Enterobacteria_phage	1.6e-62	92.8
WP_039104067.1\|1815942_1816602_-	hypothetical protein	NA	NA	NA	NA
WP_039104065.1\|1816598_1817348_-	phosphoadenosine phosphosulfate reductase family protein	NA	NA	NA	NA
WP_039104063.1\|1817826_1818612_-	hypothetical protein	A4JX52	Burkholderia_virus	1.3e-61	51.0
WP_032437708.1\|1818611_1818911_-	hypothetical protein	K7PJS4	Enterobacterial_phage	8.5e-14	48.6
WP_039104060.1\|1819768_1820464_-	helix-turn-helix transcriptional regulator	Q8HAA0	Salmonella_phage	2.7e-87	71.3
WP_001191665.1\|1820561_1820804_+	helix-turn-helix transcriptional regulator	A0A1C9IHV8	Salmonella_phage	1.3e-25	80.3
WP_000230161.1\|1820838_1821300_+	hypothetical protein	K7PJS5	Enterobacterial_phage	3.8e-69	87.5
WP_023317571.1\|1821537_1821750_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	2.2e-16	72.7
WP_039104057.1\|1821706_1822621_+	transcriptional regulator	H2DE83	Erwinia_phage	1.4e-30	60.6
WP_039104055.1\|1822617_1823427_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1C9II58	Salmonella_phage	9.1e-111	69.3
WP_000779146.1\|1823436_1823814_+	RusA family crossover junction endodeoxyribonuclease	A0A1C9IIA0	Salmonella_phage	2.3e-48	73.6
WP_039104053.1\|1823826_1824807_+	DUF968 domain-containing protein	A0A1C9IHZ5	Salmonella_phage	4.9e-135	67.8
WP_039104051.1\|1824825_1825167_+	antitermination protein	A0A0P0ZCW0	Stx2-converting_phage	2.4e-49	78.2
WP_071983260.1\|1825209_1826259_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_128205800.1\|1826262_1826835_-	hypothetical protein	NA	NA	NA	NA
WP_039104049.1\|1826831_1827545_-	hypothetical protein	NA	NA	NA	NA
WP_024176410.1\|1828376_1828676_+\|holin	holin	A0A286N2Q5	Klebsiella_phage	4.5e-39	83.8
WP_032695797.1\|1828672_1829212_+	glycoside hydrolase family 108 protein	A0A286N2Q6	Klebsiella_phage	1.5e-101	98.9
WP_039104046.1\|1829208_1829556_+	hypothetical protein	A0A286N2Q7	Klebsiella_phage	9.5e-41	82.6
WP_039104044.1\|1829552_1829828_+	hypothetical protein	G8C7W1	Escherichia_phage	1.7e-24	68.5
WP_065912073.1\|1829778_1829964_+	hypothetical protein	A0A286SGR9	Klebsiella_phage	2.0e-21	89.1
WP_039104040.1\|1830281_1830485_+	hypothetical protein	NA	NA	NA	NA
WP_039104038.1\|1830603_1830849_+	DUF2560 family protein	A0A286N2R1	Klebsiella_phage	4.2e-35	97.5
WP_107334310.1\|1831074_1831335_+	hypothetical protein	NA	NA	NA	NA
WP_014228567.1\|1831908_1832400_+	DUF1441 family protein	K7PJY2	Enterobacterial_phage	6.4e-67	84.0
WP_039104036.1\|1832399_1834508_+\|terminase	phage terminase large subunit family protein	K7PH52	Enterobacterial_phage	0.0e+00	83.2
WP_020317294.1\|1834504_1834720_+	hypothetical protein	A5LH28	Enterobacteria_phage	7.7e-25	77.1
WP_020317329.1\|1834716_1836216_+\|portal	phage portal protein	K7PHM5	Enterobacterial_phage	1.1e-247	83.6
WP_039104034.1\|1836160_1838176_+\|protease	Clp protease ClpP	K7PKX4	Enterobacterial_phage	0.0e+00	84.5
WP_014228572.1\|1838256_1838583_+	DUF2190 family protein	K7PJY3	Enterobacterial_phage	1.4e-33	66.4
WP_020317349.1\|1838575_1838869_+	sugar ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_020317346.1\|1838858_1839410_+\|tail	phage tail protein	K7P7A8	Enterobacteria_phage	5.3e-54	67.9
WP_039104031.1\|1839406_1839805_+\|tail	phage tail protein	K7PHM6	Enterobacterial_phage	1.9e-40	57.8
WP_023304948.1\|1839812_1840295_+	hypothetical protein	M9NYX0	Enterobacteria_phage	5.7e-60	68.6
WP_039104029.1\|1840337_1840733_+\|tail	phage tail protein	M9NZD7	Enterobacteria_phage	8.3e-09	28.2
WP_032420719.1\|1840753_1841071_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	1.4e-19	51.5
WP_039104025.1\|1841051_1843748_+\|tail	phage tail tape measure protein	K7PKR0	Enterobacteria_phage	2.2e-201	62.6
WP_039104023.1\|1843747_1844221_+	hypothetical protein	A0A286S298	Klebsiella_phage	1.3e-53	63.5
WP_039104022.1\|1844207_1844690_+	DUF1833 family protein	A0A286S2B1	Klebsiella_phage	5.0e-56	68.4
WP_039104020.1\|1844697_1845084_+	hypothetical protein	A0A286S2A6	Klebsiella_phage	7.3e-34	51.6
WP_039104018.1\|1845080_1848149_+	kinase	A0A286S259	Klebsiella_phage	0.0e+00	66.0
WP_039104017.1\|1848224_1850417_+	hypothetical protein	A0A2H4YH15	Raoultella_phage	5.4e-97	39.9
WP_039104015.1\|1850406_1851189_+	hypothetical protein	A0A2H4YHE3	Raoultella_phage	3.0e-18	30.2
1856781:1856845	attR	NA	NA	NA	NA

DBSCAN-SWA_4

2166128 : 2180426

Salmonella_phage(41.18%)

integrase

attL 2163792:2163805|attR 2177119:2177132

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2163792:2163805	attL	NA	NA	NA	NA
WP_032741145.1\|2166128_2167376_-\|integrase	site-specific integrase	A0A0U2JGI6	Escherichia_phage	2.1e-114	48.4
WP_012967855.1\|2167375_2167591_-	DUF1233 family excisionase	A0A0U2RY08	Escherichia_phage	7.7e-17	54.9
WP_004184543.1\|2167655_2167895_-	DUF4060 family protein	M9P0E0	Enterobacteria_phage	2.9e-25	73.1
WP_032421501.1\|2167902_2168211_-	hypothetical protein	I6PD68	Cronobacter_phage	1.1e-24	57.8
WP_039103898.1\|2168207_2168858_-	morphogenetic protein	H2BDG4	Pseudomonas_virus	7.2e-42	44.5
WP_032421692.1\|2168892_2170002_-	recombinase RecT	H6WRX0	Salmonella_phage	9.1e-186	87.0
WP_039103895.1\|2170014_2173056_-	exodeoxyribonuclease	H6WRX1	Salmonella_phage	4.9e-298	60.9
WP_023282477.1\|2173193_2173349_-	hypothetical protein	K7PGY4	Enterobacteria_phage	2.0e-14	71.2
WP_039103893.1\|2173358_2173550_-	YebW family protein	NA	NA	NA	NA
WP_039103891.1\|2174091_2174370_-	hypothetical protein	NA	NA	NA	NA
WP_039103890.1\|2174467_2174926_-	hypothetical protein	NA	NA	NA	NA
WP_039103888.1\|2175087_2175501_-	helix-turn-helix domain-containing protein	A0A0M4R5D1	Salmonella_phage	9.5e-48	79.0
WP_039103886.1\|2175570_2175798_+	Rha family transcriptional regulator	A0A0M4QX15	Salmonella_phage	4.2e-21	63.5
WP_039103884.1\|2175800_2176337_+	hypothetical protein	K7PJT7	Enterobacteria_phage	9.8e-61	70.6
WP_039104307.1\|2176465_2177260_+	ParB/RepB/Spo0J family partition protein	C7BGF1	Burkholderia_phage	6.3e-64	51.3
2177119:2177132	attR	NA	NA	NA	NA
WP_039104305.1\|2177325_2178171_+	hypothetical protein	S5MC07	Escherichia_phage	1.5e-23	52.2
WP_039103883.1\|2178173_2178923_+	ATP-binding protein	S4TNF5	Salmonella_phage	3.5e-117	81.5
WP_039103881.1\|2178930_2179275_+	DUF977 family protein	H6WRX9	Salmonella_phage	2.3e-10	43.6
WP_052251491.1\|2179258_2179729_+	hypothetical protein	NA	NA	NA	NA
WP_039103879.1\|2179725_2180208_+	class I SAM-dependent methyltransferase	H9C170	Pectobacterium_phage	5.3e-74	83.2
WP_039103878.1\|2180204_2180426_+	hypothetical protein	S4TVX5	Salmonella_phage	1.0e-11	50.0

DBSCAN-SWA_5

2185294 : 2215705

Escherichia_phage(31.03%)

terminase,coat,tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071983264.1\|2185294_2185537_+	hypothetical protein	K7PHG9	Enterobacteria_phage	1.2e-18	60.0
WP_039103870.1\|2185572_2186169_+	DUF1367 family protein	K7PKS6	Enterobacteria_phage	9.4e-89	78.6
WP_039103868.1\|2186168_2186375_+	hypothetical protein	H6WRY8	Salmonella_phage	4.8e-24	72.7
WP_004184498.1\|2186377_2186674_+	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	4.1e-37	75.0
WP_039103866.1\|2186670_2187486_+	molecular chaperone	A0A1B5FPA5	Escherichia_phage	1.8e-106	70.1
WP_023289577.1\|2187767_2188067_+	hypothetical protein	NA	NA	NA	NA
WP_039103864.1\|2188214_2188574_-	hypothetical protein	D5GW25	Campylobacter_virus	5.8e-09	34.0
WP_039103863.1\|2188852_2189128_+	hypothetical protein	NA	NA	NA	NA
WP_158514487.1\|2189605_2189764_-	hypothetical protein	NA	NA	NA	NA
WP_004213330.1\|2190400_2190796_+	membrane protein	G8C7V8	Escherichia_phage	1.5e-45	73.1
WP_012967892.1\|2190782_2191064_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	3.8e-32	72.0
WP_039103860.1\|2191063_2191690_+	glycoside hydrolase family 19 protein	F1C591	Cronobacter_phage	4.4e-89	76.8
WP_012967895.1\|2191895_2192078_-	hypothetical protein	NA	NA	NA	NA
WP_032735912.1\|2192163_2192448_+	hypothetical protein	G8C7W3	Escherichia_phage	8.6e-32	74.5
WP_110227683.1\|2192545_2192818_+	hypothetical protein	NA	NA	NA	NA
WP_139015922.1\|2193125_2193245_-	small membrane protein	NA	NA	NA	NA
WP_032735910.1\|2193798_2194158_+	hypothetical protein	NA	NA	NA	NA
WP_004184480.1\|2195433_2195679_+	DUF2560 family protein	A0A286N2R1	Klebsiella_phage	1.6e-34	97.5
WP_038421381.1\|2196237_2197233_+\|terminase	terminase small subunit	Q5QF76	Pseudomonas_virus	1.3e-34	43.8
WP_039103857.1\|2197210_2198515_+\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	3.7e-146	60.3
WP_039103855.1\|2198519_2199944_+	DUF4055 domain-containing protein	G8C7P4	Escherichia_phage	2.0e-193	71.7
WP_039103853.1\|2199927_2201040_+	phage Mu F like family protein	I6PD76	Cronobacter_phage	1.8e-109	54.1
WP_024359389.1\|2201146_2201911_+	hypothetical protein	G8C7P6	Escherichia_phage	1.4e-76	59.4
WP_039103850.1\|2201998_2203135_+\|coat	coat protein	G8C7P7	Escherichia_phage	4.8e-158	76.5
WP_016160819.1\|2203174_2203387_+	hypothetical protein	G8C7P8	Escherichia_phage	4.5e-09	53.7
WP_039103848.1\|2203390_2203801_+	hypothetical protein	A0A0H5AUF0	Pseudomonas_phage	3.9e-09	38.2
WP_071983265.1\|2203802_2204036_+	hypothetical protein	A0A1V0E8A3	Vibrio_phage	2.1e-12	51.5
WP_039104301.1\|2204022_2204406_+	hypothetical protein	A0A0S2SYG4	Pseudomonas_phage	3.5e-20	44.4
WP_039103846.1\|2204407_2204959_+	hypothetical protein	G8C7Q1	Escherichia_phage	5.9e-29	39.9
WP_039103844.1\|2204955_2205348_+	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_039103842.1\|2205371_2206304_+	hypothetical protein	A0A0D4DBN5	Acinetobacter_phage	2.8e-23	26.6
WP_023159435.1\|2206341_2206824_+	hypothetical protein	NA	NA	NA	NA
WP_145940796.1\|2206961_2207159_+	hypothetical protein	NA	NA	NA	NA
WP_077253596.1\|2207253_2207595_+	zinc ribbon domain-containing protein	S4TR42	Salmonella_phage	2.6e-06	43.3
WP_039103838.1\|2207696_2210576_+\|tail	tail protein	A0A2H4J107	uncultured_Caudovirales_phage	3.5e-104	32.9
WP_015958316.1\|2210659_2210995_+	hypothetical protein	NA	NA	NA	NA
WP_023313121.1\|2211306_2211780_+	hypothetical protein	A0A286S298	Klebsiella_phage	8.6e-61	68.6
WP_039103836.1\|2211766_2212249_+	DUF1833 family protein	A0A286S2B1	Klebsiella_phage	1.8e-82	96.2
WP_039103834.1\|2212259_2212640_+	hypothetical protein	A0A286S2A6	Klebsiella_phage	2.4e-69	95.2
WP_039103831.1\|2212636_2215705_+	kinase	A0A286S259	Klebsiella_phage	0.0e+00	97.1

DBSCAN-SWA_6

2866354 : 2875762

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162493260.1\|2866354_2867989_+	DUF4981 domain-containing protein	L0N6M2	Herpes_simplex_virus	2.6e-181	55.5
WP_012968277.1\|2868043_2869309_+	MFS transporter	NA	NA	NA	NA
WP_023340104.1\|2869339_2870428_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	9.1e-207	97.8
WP_008804980.1\|2870514_2870775_-	hypothetical protein	A0A077SK33	Escherichia_phage	3.0e-39	95.3
WP_039103359.1\|2871069_2871930_+	class A beta-lactamase LEN-17	A0A077SL40	Escherichia_phage	1.8e-144	90.9
WP_008804982.1\|2871947_2872709_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	2.1e-133	99.2
WP_032733005.1\|2872969_2873872_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	9.4e-157	98.0
WP_032730293.1\|2873883_2875149_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	2.0e-229	97.6
WP_012541792.1\|2875141_2875762_+	aldolase	A0A077SK32	Escherichia_phage	5.7e-113	98.1

DBSCAN-SWA_7

3380949 : 3412204

Salmonella_phage(20.83%)

integrase,lysis,tail

attL 3382962:3382976|attR 3416277:3416291

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023289196.1\|3380949_3382008_-	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	6.1e-14	31.1
WP_039104252.1\|3382430_3383381_-\|tail	tail fiber domain-containing protein	A0A0P0IDN1	Klebsiella_phage	2.0e-96	56.4
3382962:3382976	attL	NA	NA	NA	NA
WP_012542161.1\|3383831_3384539_-	peptidase P60	A0A2H4J1J7	uncultured_Caudovirales_phage	1.3e-60	45.4
WP_039103083.1\|3384541_3385291_-\|tail	phage minor tail protein L	K7PGX3	Enterobacteria_phage	2.0e-83	57.2
WP_039103082.1\|3385383_3385743_-	hypothetical protein	NA	NA	NA	NA
WP_039103081.1\|3385755_3386106_-\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	7.6e-22	40.0
WP_039103080.1\|3386105_3389102_-\|tail	phage tail tape measure protein	A0A2H4J7J3	uncultured_Caudovirales_phage	5.2e-34	25.8
WP_016160678.1\|3389330_3389675_-	hypothetical protein	NA	NA	NA	NA
WP_039103079.1\|3389689_3390157_-	hypothetical protein	NA	NA	NA	NA
WP_039104250.1\|3390177_3390579_-	hypothetical protein	Q6UAX1	Klebsiella_phage	7.4e-37	61.1
WP_039103078.1\|3390595_3390976_-	hypothetical protein	Q6UAX2	Klebsiella_phage	8.8e-40	66.9
WP_023289182.1\|3391772_3391997_+	hypothetical protein	NA	NA	NA	NA
WP_023289181.1\|3392035_3392473_-	hypothetical protein	NA	NA	NA	NA
WP_016160650.1\|3393421_3393772_-	hypothetical protein	R9TPM9	Aeromonas_phage	7.9e-11	38.1
WP_023317653.1\|3393768_3394266_-	lysozyme	A0A1V0E5Q7	Salmonella_phage	3.7e-78	85.2
WP_016160648.1\|3394265_3394481_-\|lysis	phage S lysis protein	A5LH82	Enterobacteria_phage	2.7e-30	88.7
WP_139042930.1\|3395398_3395518_+	small membrane protein	NA	NA	NA	NA
WP_128316005.1\|3396286_3396490_+	hypothetical protein	NA	NA	NA	NA
WP_039103077.1\|3396732_3397335_-	hypothetical protein	H9C175	Pectobacterium_phage	1.9e-76	68.6
WP_039103076.1\|3397351_3398383_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.2e-96	49.6
WP_023289175.1\|3398582_3398975_-	hypothetical protein	K7PHB4	Enterobacterial_phage	1.0e-11	35.6
WP_077256314.1\|3399015_3399306_-	hypothetical protein	H6WRY6	Salmonella_phage	6.1e-17	56.9
WP_039103075.1\|3399317_3399551_-	DinI-like family protein	K7PM44	Enterobacteria_phage	2.3e-22	64.9
WP_145940800.1\|3400000_3401086_+	hypothetical protein	Q684B3	Sulfolobus_virus	2.6e-12	25.7
WP_145940801.1\|3401096_3402140_+	AAA family ATPase	Q56VQ0	Pseudomonas_phage	4.3e-12	25.4
WP_071983293.1\|3402143_3403013_+	SIR2 family protein	NA	NA	NA	NA
WP_039103074.1\|3403193_3403538_-	hypothetical protein	NA	NA	NA	NA
WP_039104246.1\|3403534_3403798_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_039104244.1\|3403847_3404312_-	replication protein	A0A0U2JGJ0	Escherichia_phage	4.1e-63	71.5
WP_077269953.1\|3404304_3405309_-	DNA-binding protein	A0A0U2RT81	Escherichia_phage	4.3e-33	40.9
WP_039103073.1\|3405368_3405923_-	hypothetical protein	NA	NA	NA	NA
WP_004147982.1\|3405925_3406147_-	Cro/Cl family transcriptional regulator	H6WRX5	Salmonella_phage	1.2e-28	75.3
WP_004147981.1\|3406417_3406672_+	hypothetical protein	H6WRX4	Salmonella_phage	1.6e-13	54.8
WP_052251466.1\|3406993_3407236_-	hypothetical protein	NA	NA	NA	NA
WP_145940802.1\|3407294_3407690_-	hypothetical protein	NA	NA	NA	NA
WP_039103071.1\|3407936_3408131_+	DUF1482 family protein	NA	NA	NA	NA
WP_014228879.1\|3408173_3408518_+	transcriptional regulator	NA	NA	NA	NA
WP_039103070.1\|3408659_3410798_+	exonuclease	H6WRX1	Salmonella_phage	1.1e-99	42.9
WP_012542206.1\|3410850_3411096_+	excisionase	NA	NA	NA	NA
WP_023328117.1\|3411076_3412204_+\|integrase	tyrosine-type recombinase/integrase	O21925	Phage_21	4.4e-119	58.4
3416277:3416291	attR	NA	NA	NA	NA

DBSCAN-SWA_8

3664690 : 3739780

Cronobacter_phage(55.81%)

terminase,protease,integrase,tRNA,portal,head,capsid,tail,holin

attL 3708505:3708525|attR 3739858:3739878

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023297317.1\|3664690_3666412_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	4.5e-14	34.0
WP_162493280.1\|3666433_3667156_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|3667507_3667726_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_012542332.1\|3667844_3670124_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	3.7e-165	42.0
WP_002896520.1\|3670154_3670472_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896516.1\|3670797_3671019_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_039103032.1\|3671085_3673026_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	2.9e-38	41.0
WP_008805838.1\|3673022_3674138_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7
WP_008805837.1\|3674275_3675934_-	ATP-dependent endonuclease	NA	NA	NA	NA
WP_002896434.1\|3676353_3677049_+	aquaporin Z	NA	NA	NA	NA
WP_032732737.1\|3677164_3678064_+	lysine exporter LysO family protein	NA	NA	NA	NA
WP_012968625.1\|3678207_3679860_+	hydroxylamine reductase	NA	NA	NA	NA
WP_032732736.1\|3679870_3680839_+	NADH oxidoreductase	NA	NA	NA	NA
WP_016160554.1\|3681046_3681481_-	DoxX family protein	NA	NA	NA	NA
WP_008805831.1\|3681632_3683351_+	ubiquinone-dependent pyruvate dehydrogenase	NA	NA	NA	NA
WP_023297312.1\|3683389_3684391_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_039103030.1\|3684401_3685844_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_008805828.1\|3685931_3686945_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_008805827.1\|3686941_3687772_-	N-acetylmuramoyl-L-alanine amidase	A0A1B0UZW5	Roseobacter_phage	2.4e-05	31.6
WP_016160551.1\|3687803_3688943_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_008805825.1\|3689304_3689577_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_012968629.1\|3689831_3690347_+	lipoprotein	NA	NA	NA	NA
WP_012968630.1\|3690573_3691302_+	arginine ABC transporter ATP-binding protein ArtP	G9BWD6	Planktothrix_phage	2.7e-29	36.7
WP_002896390.1\|3691322_3692054_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002896386.1\|3692060_3692777_+	arginine ABC transporter permease ArtQ	NA	NA	NA	NA
WP_008805822.1\|3692776_3693445_+	arginine ABC transporter permease ArtM	NA	NA	NA	NA
WP_008805821.1\|3693629_3694361_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_039103029.1\|3694444_3695917_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	6.7e-27	31.4
WP_012542345.1\|3695913_3696630_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.0e-33	36.4
WP_039103028.1\|3696708_3697836_-	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	A0A2K5B251	Erysipelothrix_phage	6.1e-20	26.2
WP_008805817.1\|3697877_3698366_-	DUF2593 family protein	NA	NA	NA	NA
WP_002896372.1\|3698423_3699269_-	putrescine ABC transporter permease PotI	NA	NA	NA	NA
WP_008805816.1\|3699265_3700219_-	putrescine ABC transporter permease PotH	NA	NA	NA	NA
WP_008805815.1\|3700229_3701396_-	putrescine ABC transporter ATP-binding subunit PotG	G3M9Y6	Bacillus_virus	3.0e-30	34.9
WP_002896368.1\|3701526_3702639_-	spermidine/putrescine ABC transporter substrate-binding protein PotF	NA	NA	NA	NA
WP_002896365.1\|3702987_3703467_-	YbjN domain-containing protein	NA	NA	NA	NA
WP_012542349.1\|3703555_3704458_-	30S ribosomal protein S6--L-glutamate ligase	A0A1D7SR78	Cyanophage	7.0e-35	34.5
WP_022065296.1\|3704572_3705295_-	nitroreductase NfsA	NA	NA	NA	NA
WP_008805812.1\|3705278_3705566_-	YbjC family protein	NA	NA	NA	NA
WP_002896352.1\|3705768_3706032_+	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	1.6e-27	73.1
WP_008805811.1\|3706038_3706422_-	membrane protein	NA	NA	NA	NA
WP_008805810.1\|3706689_3708375_+	aspartate:alanine antiporter	NA	NA	NA	NA
WP_012542352.1\|3708366_3708489_-	hypothetical protein	NA	NA	NA	NA
3708505:3708525	attL	NA	NA	NA	NA
WP_039103027.1\|3708615_3709734_-	DUF4935 domain-containing protein	NA	NA	NA	NA
WP_145940804.1\|3710029_3710305_-	hypothetical protein	NA	NA	NA	NA
WP_039103026.1\|3710405_3712085_-	hypothetical protein	F1BUJ7	Cronobacter_phage	2.0e-189	59.2
WP_039103025.1\|3712088_3712640_-	hypothetical protein	F1BUJ9	Cronobacter_phage	5.7e-56	68.9
WP_039103024.1\|3712611_3713337_-	hypothetical protein	F1BUK1	Cronobacter_phage	1.0e-52	47.5
WP_039103022.1\|3713336_3713576_-	hypothetical protein	NA	NA	NA	NA
WP_052251464.1\|3713598_3716211_-	hypothetical protein	F1BUK3	Cronobacter_phage	1.3e-94	60.5
WP_039103021.1\|3716219_3716858_-	hypothetical protein	F1BUK5	Cronobacter_phage	1.0e-72	70.9
WP_039103020.1\|3716850_3718035_-	phage protein	F1BUK6	Cronobacter_phage	6.5e-174	76.0
WP_039103019.1\|3718031_3718361_-	DUF2590 family protein	F1BUK8	Cronobacter_phage	4.9e-39	72.4
WP_039103018.1\|3718357_3720241_-\|tail	phage tail tape measure protein	F1BUK9	Cronobacter_phage	2.1e-222	60.1
WP_039103017.1\|3720428_3720692_-	hypothetical protein	A5X9I7	Aeromonas_virus	7.0e-20	56.5
WP_039103015.1\|3720838_3721171_-	hypothetical protein	F1BUL2	Cronobacter_phage	5.7e-35	70.9
WP_039103014.1\|3721170_3721512_-	M15 family metallopeptidase	F1BUL3	Cronobacter_phage	3.8e-50	90.1
WP_039103013.1\|3721508_3721799_-\|holin	holin	C7BGD7	Burkholderia_phage	8.8e-16	50.6
WP_039103012.1\|3721808_3722267_-	DUF2597 family protein	F1BUL4	Cronobacter_phage	3.9e-58	74.7
WP_039103011.1\|3722263_3723382_-	DUF2586 domain-containing protein	F1BUL5	Cronobacter_phage	8.1e-150	71.2
WP_039103010.1\|3723368_3724085_-	hypothetical protein	F1BUL6	Cronobacter_phage	9.3e-91	73.5
WP_039103009.1\|3724084_3724588_-\|tail	phage tail protein	F1BUL7	Cronobacter_phage	4.5e-60	64.2
WP_039103008.1\|3724584_3725037_-\|head	head completion/stabilization protein	F1BUL8	Cronobacter_phage	3.9e-63	82.0
WP_039103007.1\|3725133_3725835_-\|terminase	terminase	F1BUM0	Cronobacter_phage	1.7e-81	62.9
WP_039103006.1\|3725837_3726860_-\|capsid	phage major capsid protein, P2 family	F1BUM2	Cronobacter_phage	7.6e-155	80.0
WP_039103005.1\|3726921_3727716_-\|capsid	phage capsid scaffolding protein	F1BUM4	Cronobacter_phage	4.1e-63	59.0
WP_039103004.1\|3727888_3729661_+\|terminase	terminase	F1BUM5	Cronobacter_phage	7.0e-289	81.6
WP_039103003.1\|3729657_3730707_+\|portal	phage portal protein	F1BUM7	Cronobacter_phage	1.5e-153	75.7
WP_039103002.1\|3730703_3731027_+	ogr/Delta-like zinc finger family protein	F1BUM8	Cronobacter_phage	1.7e-44	86.0
WP_052251462.1\|3731326_3733393_-	replication endonuclease	F1BUS0	Erwinia_phage	8.4e-201	57.4
WP_039103001.1\|3733389_3734247_-	DNA adenine methylase	F1BUN1	Cronobacter_phage	3.0e-128	80.3
WP_039103000.1\|3734237_3734471_-	DUF2732 family protein	NA	NA	NA	NA
WP_052251460.1\|3734536_3734734_-	hypothetical protein	NA	NA	NA	NA
WP_032411117.1\|3734733_3735162_-	hypothetical protein	F1BUN5	Cronobacter_phage	1.8e-25	50.4
WP_039102999.1\|3735354_3735858_-	hypothetical protein	F1BUN6	Cronobacter_phage	1.8e-56	69.5
WP_071983319.1\|3735894_3736113_-	regulator	NA	NA	NA	NA
WP_039102998.1\|3736241_3736805_+	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	1.7e-34	40.2
WP_039102997.1\|3738068_3738650_+	hypothetical protein	NA	NA	NA	NA
WP_162493329.1\|3738835_3739780_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	2.6e-88	53.4
3739858:3739878	attR	NA	NA	NA	NA

DBSCAN-SWA_9

4868245 : 4874060

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039102776.1\|4868245_4870579_-	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	84.0
WP_014837515.1\|4870590_4870911_-	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_039102775.1\|4870907_4871135_-	hypothetical protein	NA	NA	NA	NA
WP_162493346.1\|4871131_4871677_-	host cell division inhibitor Icd-like protein	Q7M2A7	Enterobacteria_phage	3.3e-32	69.3
WP_039102774.1\|4871679_4871946_-	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.4e-30	70.5
WP_039102773.1\|4872496_4873234_+	glycoprotein 3	Q7M2A2	Enterobacteria_phage	2.9e-71	59.8
WP_004098164.1\|4873230_4873476_+	hypothetical protein	Q7M294	Enterobacteria_phage	5.0e-20	59.3
WP_039102772.1\|4873493_4874060_+	Polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.3e-58	63.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP009275

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP009275_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009275_1

52707-53398

Orphan

Consensus_repeat	Method
GAATGCTGCCTGGGACCACGGTCCCA	CRT

15 spacers

The CRISPR arrays of NZ_CP009275_1

>merge|NZ_CP009275|1|52707-53398|CRT
CCTGTCAGTCTGGGACCACGGTCTCACCTTTACCGTCAGCGCCGGAATGCTGCCTCTGGGACCACGGTCCCAACTTCCCGGTCAGCGCCGGAATGCTGCCTGGGACCACGGTCCCAACTTCCCGGTCAGCGCCGGAATGTTGCCTGGGACCACGGTCCCAACTTCCCGGTCAGCGCCGGAATGCTGCCTGGGACCACGGTCCCAACTTCCCGGTCAGCACCGGAATGCTGCCTGGGACCACGGTCCCAACTTCCCGGTCAGCGCCGGAATGCTGCCTGGGACCACGGTCCCAACTTCCCGGTCAGCACCGGAATGCTGCCTGGGACCACGGTCCCAACTTCCCGGTCAGCGCCGGAATGCTGCCTGGGACCGCGGTCCCACCTTTACCATCAGTACCGGAATGCTGCCTGGGACCACGGTCCCAACTTCCCGGTCAGCGCCGGAATGCTGCCTGGGACCACGGTCCCACCTTTACCGTCAGTACCGGAATGCTGCCTGGGACCATGGTCCCAACTTCCCGGTCAGCGCCGGAATGCTGCCTCTGGGACCACGGTCCCACCTTTACCGTCAGCGCCGGAATGCTGCCTGGGACCATGGTCCCAACTTCCCGGTCAGCGCCGGAATGCTGCCTCTGGGACCACGGTCCCACCTTTACCGTCAGCGCCGGAATGCTGCCTGGGACCACGGTCCCA

>NZ_CP009275|1|1|52707-53398|CRT
CCTGTCAGTCTGGGACCACGGTCTCA	CCTTTACCGTCAGCGCCGGA
ATGCTGCCTCTGGGACCACGGTCCCA	ACTTCCCGGTCAGCGCCG
GAATGCTGCCTGGGACCACGGTCCCA	ACTTCCCGGTCAGCGCCG
GAATGTTGCCTGGGACCACGGTCCCA	ACTTCCCGGTCAGCGCCG
GAATGCTGCCTGGGACCACGGTCCCA	ACTTCCCGGTCAGCACCG
GAATGCTGCCTGGGACCACGGTCCCA	ACTTCCCGGTCAGCGCCG
GAATGCTGCCTGGGACCACGGTCCCA	ACTTCCCGGTCAGCACCG
GAATGCTGCCTGGGACCACGGTCCCA	ACTTCCCGGTCAGCGCCG
GAATGCTGCCTGGGACCGCGGTCCCA	CCTTTACCATCAGTACCG
GAATGCTGCCTGGGACCACGGTCCCA	ACTTCCCGGTCAGCGCCG
GAATGCTGCCTGGGACCACGGTCCCA	CCTTTACCGTCAGTACCG
GAATGCTGCCTGGGACCATGGTCCCA	ACTTCCCGGTCAGCGCCGGA
ATGCTGCCTCTGGGACCACGGTCCCA	CCTTTACCGTCAGCGCCG
GAATGCTGCCTGGGACCATGGTCCCA	ACTTCCCGGTCAGCGCCGGA
ATGCTGCCTCTGGGACCACGGTCCCA	CCTTTACCGTCAGCGCCG
GAATGCTGCCTGGGACCACGGTCCCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009275.1\|WP_032740676.1\|51647_52613_+\|ParB/RepB/Spo0J-family-plasmid-partition-protein	unknown	unknown	gnl\|CDD\|184254
NZ_CP009275.1\|WP_040107986.1\|61486_61993_+\|antirestriction-protein	unknown	unknown	gnl\|CDD\|227077
NZ_CP009275.1\|WP_032740675.1\|48729_49740_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP009275.1\|WP_040107911.1\|62035_62227_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009275.1\|WP_000523815.1\|50481_51648_+\|plasmid-partitioning-protein-SopA	unknown	unknown	gnl\|CDD\|184261
NZ_CP009275.1\|WP_110218927.1\|42639_42972_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009275.1\|WP_040107984.1\|56127_57030_-\|inorganic-pyrophosphatase	unknown	unknown	gnl\|CDD\|235458
NZ_CP009275.1\|WP_040107912.1\|62427_62682_+\|DNA-polymerase-III-subunit-theta	unknown	unknown	gnl\|CDD\|368909
NZ_CP009275.1\|WP_040107904.1\|39817_41191_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009275.1\|WP_040107910.1\|61013_61442_+\|antirestriction-protein	unknown	unknown	gnl\|CDD\|377006
NZ_CP009275.1\|WP_024144810.1\|46294_46561_+\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	unknown	unknown	gnl\|CDD\|274227
NZ_CP009275.1\|WP_040107909.1\|58814_60386_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NZ_CP009275.1\|WP_032740678.1\|54393_55683_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP009275.1\|WP_032740681.1\|58109_58406_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009275.1\|WP_001515717.1\|47206_47947_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NZ_CP009275.1\|WP_040107907.1\|53922_54312_-\|fluoride-efflux-transporter-CrcB	unknown	unknown	gnl\|CDD\|184564
NZ_CP009275.1\|WP_000026497.1\|44390_46064_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009275.1\|WP_040107903.1\|38776_39700_+\|J-domain-containing-protein	unknown	unknown	gnl\|CDD\|365959
NZ_CP009275.1\|WP_040107908.1\|55699_56125_-\|universal-stress-protein	unknown	unknown	unknown
NZ_CP009275.1\|WP_040107905.1\|41454_42075_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP009275.1\|WP_032740676.1\|51647_52613_+\|ParB/RepB/Spo0J-family-plasmid-partition-protein	gnl\|CDD\|184254	PRK13698, PRK13698, ParB/RepB/Spo0J family plasmid partition protein.	0
NZ_CP009275.1\|WP_040107986.1\|61486_61993_+\|antirestriction-protein	gnl\|CDD\|227077	COG4734, ArdA, Antirestriction protein [General function prediction only].	2.85888e-39
NZ_CP009275.1\|WP_032740675.1\|48729_49740_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	0.000156777
NZ_CP009275.1\|WP_000523815.1\|50481_51648_+\|plasmid-partitioning-protein-SopA	gnl\|CDD\|184261	PRK13705, PRK13705, plasmid-partitioning protein SopA; Provisional.	0
NZ_CP009275.1\|WP_040107903.1\|38776_39700_+\|J-domain-containing-protein	gnl\|CDD\|365959	pfam00226, DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.	3.70343e-21
NZ_CP009275.1\|WP_040107984.1\|56127_57030_-\|inorganic-pyrophosphatase	gnl\|CDD\|235458	PRK05427, PRK05427, putative manganese-dependent inorganic pyrophosphatase; Provisional.	7.92665e-90
NZ_CP009275.1\|WP_040107912.1\|62427_62682_+\|DNA-polymerase-III-subunit-theta	gnl\|CDD\|368909	pfam06440, DNA_pol3_theta, DNA polymerase III, theta subunit. DNA polymerase III (EC 2.7.7.7) is comprised of three tightly associated subunits, alpha, epsilon and theta. This family contains the theta subunit. The structure of the theta subunit shows that the N-terminal two thirds is comprised of three helices while the C-terminal third is disordered. The function of the theta subunit is poorly understood, but the interaction of the theta subunit with the epsilon subunit is thought to enhance the 3' to 5' exonucleolytic proofreading activity of epsilon.	2.70748e-31
NZ_CP009275.1\|WP_032740678.1\|54393_55683_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP009275.1\|WP_024144810.1\|46294_46561_+\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	gnl\|CDD\|274227	TIGR02606, Antitoxin_ParD, putative addiction module antidote protein, CC2985 family. This bacterial protein family has a very similar seed alignment to that of pfam03693 but is a more stringent model with higher cutoff scores. Proteins that score above the trusted cutoff to this model almost invariably are found adjacent to a ParE family protein (pfam05016), where ParE is the killing partner of an addiction module for plasmid stabilization. Members of this family, therefore, are putative addiction module antidote proteins. Some are encoded on plasmids or in prophage regions, but others appear chromosomal. A genome may contain several identical copies, such as the four in Magnetococcus sp. MC-1. This family is named for one member, CC2985 of Caulobacter crescentus CB15. [Cellular processes, Other, Mobile and extrachromosomal element functions, Plasmid functions].	9.78288e-16
NZ_CP009275.1\|WP_040107909.1\|58814_60386_+\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.40932e-61
NZ_CP009275.1\|WP_040107910.1\|61013_61442_+\|antirestriction-protein	gnl\|CDD\|377006	pfam03230, Antirestrict, Antirestriction protein. This family includes various protein that are involved in antirestriction. The ArdB protein efficiently inhibits restriction by members of the three known families of type I systems of E. coli.	1.01068e-29
NZ_CP009275.1\|WP_001515717.1\|47206_47947_+\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	2.21329e-24
NZ_CP009275.1\|WP_040107907.1\|53922_54312_-\|fluoride-efflux-transporter-CrcB	gnl\|CDD\|184564	PRK14196, PRK14196, fluoride efflux transporter CrcB.	7.04312e-59

>NZ_CP009275.1|WP_032740676.1|51647_52613_+|ParB/RepB/Spo0J-family-plasmid-partition-protein
MKRAPVIPRHTANTQAAEDTSAPAAPMVDSLIARVGAMARGNAITLPVCGREVKFTLEVLRGDIVETASRVWSGNERDQELLTEDALDDLIPSFLLTGQQTPAFGRRVSDIIEIADGSRRRKAAILTESDYRILVGELDDEQMSALSRLGNDYRPTSAYERGQRYANRLQNEFAGNISALADAENISRKIITRCINTARLPKSVVALFSHPGELSARSGEALQKAFADKEELLKQQAATLHDQKKAGVIFEAEEVISLLTSVLKKSPASRVNLSSRHQFAPGATALYRGDKVVLNLDRSRLPAECIEKIEAILKALEEPKS
>NZ_CP009275.1|WP_000523815.1|50481_51648_+|plasmid-partitioning-protein-SopA
MGLMDTLNQCITAGHEMTKAIAIAQFNDDSPEARKITRRWRIGEAADLVGVSSQAIRDAEKAGRLPHPDMETRGRVEQRVGYTIEQINHMRDVFGTRLRRAEDAFPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDLHIHAEDTLLPFYLGEKDDASYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPTDPHLMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQFFDMLRDLLRNVDLKGFEPDVRILLTKYSNNNGSQSPWMEEQIRDAWGSMVLKNVVRETDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR
>NZ_CP009275.1|WP_032740675.1|48729_49740_-|replication-initiation-protein
MTSENNSLPLNLQEVDKTTGEVVKLDVNSTSTVQPVALMRLGLFVPTLKSTSRSKANRKNVTDATEELVQLSIAKSEGYTDVKITGSRLDMDTDFKVWLGIIRSMSEYGVKSDTLELSFVEFVKMCGFDSRRSNKKMRDRISNSLFKLASVTLKFQSETKGWTTHLVQSAYYDINEDIVEIKAEPKLFELYHMDRRVLLRLKAIDALQRKESAQALYTYIESLPQNPAPISMKRMRDRLNLTSNVYTQNHTVRKAMEQLRDIGYLDYTEFKRGRATYFSVHYRNPKLISGTVKVPRREEEEQAPEQNYDEVIKALKAAGIDPQKLAEALSAMKPEN
>NZ_CP009275.1|WP_001515717.1|47206_47947_+|site-specific-integrase
MNSIIPLQNSPERVSLLPIAPGVDFATAVALRRMATSTGATPAYLLAPEVSALLWYMPDQRHHMLFATMWNTGIRIGEARTLTPESFDLDGLRPFVRVLSEKVRARRGRPPKDEVRLVPLTDASFVRQMESWMVTTRPRRREPLWPVTDETMRNWLKQAVKRAEADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHKDPRSMEVYTRVFALDMAATLAVPFTGDGRDAAEILRSLPPAG
>NZ_CP009275.1|WP_024144810.1|46294_46561_+|type-II-toxin-antitoxin-system-ParD-family-antitoxin
MARTITVDLGHELRDFIESLIESGDYRTQSEVIRESLRLLREKQAESRLQTLRNLLAEGLSSGEPVVWEKDAFLKKVKAGTKPAGEKR
>NZ_CP009275.1|WP_000026497.1|44390_46064_+|hypothetical-protein
MSINPIIIRQNFKIGELDAESDTLLLENCFIDSGYLSKLLNPSDTSSIVIGRTGAGKSALLHMVANKAHKYKKLDPNDISIGFLEHSDIISFFEELNVNLDMFYKVLWRHILIMELLKIRHDIKSESDTNSFFSNLLSRLKKDEIKRKALEYFREWGDKFWIDTDTHLREITYKLERDTKASIGTEYSAVNLSAEYAKKLTEEQIHDVKKRANEVVSRLQIQKLNEILSLLAEYSFDDPQKNYYIIIDQLDDNWAENDTRYKFIRALIEEIKVFRKIKNIKIIAALRLDLLRSVFNITRGSGFQEEKYESYILDIKWTSQQLTELVQKRVREVYKRQYTREDVTIKDIFPKAKGGHLGITPIEYIIERTLFRPRDVLQYVNECFNVALNRERISWDSIHKAEAVYSLKRLRSLKEEWGDIYPSFEETIEILRNLPDKFSRTSMSKNTIDAVLSELSIQNTTDPCAITANKFLEGESREQDVINEIMLCLYTVGIVGFKISSLTPYKWAFRDSTPTTKNEIKRASLMKIHKMLHSALDIRIITGNRYERDDEEDIECS
>NZ_CP009275.1|WP_110218927.1|42639_42972_+|hypothetical-protein
MGDKKKVDLTSMYRALKELGHRRIWLRIIKSGDLLFMVTFENRRLARFDRSLNTWCFVKNAALVDDYPLGSVPDGEGLTELHEKDEQLFHLTLCDEDVDRLLSYLATLDD
>NZ_CP009275.1|WP_040107905.1|41454_42075_-|hypothetical-protein
MPTKHIDDATAAQLDDLYVRCVTLTQQPVKEVEVLRLAIQTGIGNISDNDILASMAVKATVWERLAGDVWTAVTKEWPAAGIHSKNFNEMAERHSPLWKTFTSNVCRDAIRSVLKRDLENNLLNDLFGWSEAFTEEEKEREEKERNQKDKEYRKSLPFLDGRLYSSLSEHEQNIAVYYSEHGSFVSFTPDGKDDFQVQVQLREDGQ
>NZ_CP009275.1|WP_040107904.1|39817_41191_-|hypothetical-protein
MYNNLPSLTESILWDERLLSADYAALSEDALRSALEDYLQGVNASRGEWHPPEASLLSLWIARHDQLALYRPGLLSAERIILTDALEEAALRMDNVEMVVATDLLVQRRTTDRLQGIRTEVAKFVRFVKDNFVLIQAGFIAFTPCESARQEQVRKMQLLQDNPDRHFLNGVMPPAVAQLYERSLTVRGISRVSDEGHYRFVSEKTLPDEIMLELRDCLSPFTNAYMYQEMQPVEVKEDGTFRARITRGKHESRKGYDRWVRGAINRSIYFHYHGLLTDISQSARTGASLVTRCPLQGKILQKLDASGRLSRRMLELDIPFLHDLSLEDIFRIRTDYEPSVAAFRRSLRDAALDMEQASGAEAIRLLQQRFRERIADEGLEELRQKLSAWKRQSLQDTTLLALPAVLGFMGAPSVSALATGAASLIQAALGACRSHSEITRHPSWFLFRTSESKRLRR
>NZ_CP009275.1|WP_040107903.1|38776_39700_+|J-domain-containing-protein
MKKNPGFQTHYDNLKVSQDAPYEIIQAAYRTLAKKYHPDLNKQDPECARIMKIINESYVVLSDPEKRRQHDSWITKEKWRVRALENQEAREMQETVSQDTTVRNIRPAPHIREPDSSSLIHFFKQMGISFAKRILIVVVFFGGFYLYDSSNSVSSTSGEKQSAPQSSGALCSSGVYTYTNGQPWPQNATVLAYNDQQKGLSTLELDNSVNNQYLFVRLVYASNKFTHNAVREAFLPAHQKLLFTSVEPGRYAVKIKDIVTGCSQISEEMLFTEQTSGREVSYTEGSLTLYPVRNGNTHLSEITDSQF
>NZ_CP009275.1|WP_040107907.1|53922_54312_-|fluoride-efflux-transporter-CrcB
MGRFSLSQLLAIMIGGATGCVIRWFLGIKLNSFYPSIPPGTLMVNLMGAFIIGAAMAYFMRHPQLDPAWKLFIVTGLCGGLTTFSTFSVEVFSLLQTGNYLSALTSVLVHVVGSLLMTAAGFYLIMLLI
>NZ_CP009275.1|WP_032740678.1|54393_55683_-|phosphopyruvate-hydratase
MNFLLEKVTAREILDSRGNPTVEVDAFTSDGQMARASVPSGASTGSREATERRDGDTGRFSGKGVRDAIKAVETEIYDAVRGTDVREQRRLDNLMRELDGTETKSRLGANAILGVSLAVARLASQVTRQPLYRYLGGLNASLLPVPCMNIINGGVHARGQGADFQEFMIAPHGASSLTEAIRQGSEVYQALRQILLSRNLSAAVGDEGGFAPAVSSNRDPLEFIVQAIEKAGYRPGEDISICMDPASSEFYRDGKYHLRTENSALSSEEMTDYYGELMSQFPIVLLEDGLAEDDWTGWKYLHNTLGGRAELVGDDLFVTNVKYIQRGIEENLASAALIKLNQIGTLSETFDAVSLCHENGWGAFISHRSGETIDTFIADMTVALRAGHLKTGAPCRGERIEKYNQLMRIEQELGSDARYAGIKAFVRRG
>NZ_CP009275.1|WP_040107908.1|55699_56125_-|universal-stress-protein
MKIYTHALVLVQGKEDGVPLLALATTLSSMLQMKITIAHICNDYREMNYISDSLMNDALSKEVVLAKALLSELTSSVAEQVNARELVTMRRFEDVQKCINDTGADLVIAGHRNRFMGALTSRSAEYVNHLNVDVLIKHIHD
>NZ_CP009275.1|WP_040107984.1|56127_57030_-|inorganic-pyrophosphatase
MINVFGHLNPDSDAVCTATVTAGWLNRCNRPARAWRPGEVNPETHYIFEAATLTLPPLLDISLKDEPVWLVDFTEPAQGPADLFQSNIIGIIDHHRLGGLITQLPPEVWIKPAGSSATVLWLLMDTEMRRTMPPAHAILLLGALLSDTVNLCSPTTTQDDIRSATELCVLSGVKRTAFARGLLTAKTDITGMSAEQLLHKDLKAFSLAGMNVRIAQLEVSSPDQVTPLLDELQSAMVQLAVMTEAGLIVLMVTDIHTCCSSLYFAGPEGISAAPCFVTGMVSRKKQLLPWLEHHLSQSRR
>NZ_CP009275.1|WP_032740681.1|58109_58406_-|hypothetical-protein
MKQVRIYTLKDTQSAEIYFHRHWPRHMVSLPAFNIYVNHVYLGNECQVIATVTYQKDADIQAINQKYMKSDAFMSDMEGFDMSSILRVDEISIKEALF
>NZ_CP009275.1|WP_040107909.1|58814_60386_+|GGDEF-domain-containing-protein
MNNYKIRLRTLITALSTGAVVLTGTMLLCIMIVFQRDSIEESTVQNNIAYARKLADTTDRYLTIAQSELRWSSGQIHDLSASDELVREADRLRLQSGFFNSVVIVNSERVVRATSPESLGLVGKILTSDASIRTVKNQVASISEPFISAAGNYVVFLSQPIFSEHGVYLGYMGGTIYLKKHSMLSDILSQHFYPPETDIKIVDGNGMVVFSHDPDTVGTVENISPEIHYQLNSSQSGKLSLANNNRDYVAGFARLRQTDWSIWISGSEKEVDALVNHSVKKIVGFITLVVFFVAILMIYLGTLVATPLERLANAVKAGSSQRSDPSVLQNIKGWYYEAQELKEAVKQNLISTQTKLKAFSEQAIKDPLTGLYNRRGFEKMYESISSGKQVNIIAIDIDHFKQVNDRFGHDAGDKVLQELATLLKEICRENDFICRFGGEEFVIVIPEKKSDEVIDIAERIRKQTETTIFPFVGHLTLSAGVASSQYFGEDINELLRRADEFLYVAKRSGRNAVVSVQNKYQFN
>NZ_CP009275.1|WP_040107910.1|61013_61442_+|antirestriction-protein
MQYVTTRPVLNVEECDRLSFMPYLFGTDFMLAELQVYALAKQWMPEYSSEFWHFIRLPEGGGYMMPDCGRVHLVNSENWFDRIVSADAAGIILTSLAVNRRLAANHDSSNPALTRLYMLRDAQLWNHITLHPECSAIYAALD
>NZ_CP009275.1|WP_040107986.1|61486_61993_+|antirestriction-protein
MNSSVTVPAVYVGTYHQYNGGSIFGKWFDLTDFDDEDEFYDACRALHAAEDDPDFMFQDWEGIPSQFASESSVKWAFIEAFRQAQDEGRAAAFVAWAEYTGECDYDAFDDAYCGEAESEEDFAYGFVEDHGLLNEVPEFLRVYFDYEAYARDLFSSGYVFHEGYVFSN
>NZ_CP009275.1|WP_040107911.1|62035_62227_+|hypothetical-protein
MKLAPQSRDILRQYKALMNARRRDAGQRELTTAQVMDEICYYMTCQCAVYIGGHFILQGGKGQ
>NZ_CP009275.1|WP_040107912.1|62427_62682_+|DNA-polymerase-III-subunit-theta
MSKWNIASFPKEEQDNVAVDKVAAAVAWQERMSKPVVPELVEREQPEHLREYFHERLRVHRLNSQQLPRANAPEYNKPGDDQQN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP009275_1	1.11\|53175\|18\|NZ_CP009275\|CRT	53175-53192	18	NZ_CP009274.2	4451881-4451898	1	0.944
NZ_CP009275_1	1.13\|53265\|18\|NZ_CP009275\|CRT	53265-53282	18	NZ_CP009274.2	321380-321397	1	0.944
NZ_CP009275_1	1.15\|53355\|18\|NZ_CP009275\|CRT	53355-53372	18	NZ_CP009274.2	321380-321397	1	0.944

1. spacer 1.11|53175|18|NZ_CP009275|CRT matches to position: 4451881-4451898, mismatch: 1, identity: 0.944

cctttaccgtcagtaccg	CRISPR spacer
ccgttaccgtcagtaccg	Protospacer
** ***************

2. spacer 1.13|53265|18|NZ_CP009275|CRT matches to position: 321380-321397, mismatch: 1, identity: 0.944

cctttaccgtcagcgccg	CRISPR spacer
cctttaccatcagcgccg	Protospacer
********.*********

3. spacer 1.15|53355|18|NZ_CP009275|CRT matches to position: 321380-321397, mismatch: 1, identity: 0.944

cctttaccgtcagcgccg	CRISPR spacer
cctttaccatcagcgccg	Protospacer
********.*********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	52733-52752	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	53265-53284	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	53355-53374	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	CP008701	Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence	65309-65328	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	CP008701	Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence	65441-65460	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	CP008701	Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence	65485-65504	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP011633	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence	57572-57591	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	25839-25858	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	26105-26124	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	26547-26566	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_LR130540	Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2	162385-162404	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_LR130540	Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2	162695-162714	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	181750-181769	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	182458-182477	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	106605-106624	1.0
NZ_CP009275_1	1.1\|52733\|20\|NZ_CP009275\|CRT	52733-52752	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	107137-107156	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	52779-52798	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	52823-52842	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	52867-52886	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	52955-52974	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	53043-53062	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	53131-53150	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	53219-53238	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	53309-53328	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	CP008701	Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence	65265-65284	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	CP008701	Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence	65353-65372	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	CP008701	Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence	65397-65416	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP011633	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence	57616-57635	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP011633	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence	57660-57679	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP011633	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence	57704-57723	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	25885-25904	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	25929-25948	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	26017-26036	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	26151-26170	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	26283-26302	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_LR130540	Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2	162121-162140	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_LR130540	Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2	162431-162450	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	181884-181903	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	182016-182035	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	182148-182167	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	182236-182255	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	182324-182343	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	106827-106846	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	106915-106934	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	106959-106978	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	107003-107022	1.0
NZ_CP009275_1	1.12\|53219\|20\|NZ_CP009275\|CRT	53219-53238	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	107047-107066	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	52779-52798	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	52823-52842	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	52867-52886	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	52955-52974	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	53043-53062	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	53131-53150	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	53219-53238	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP009275	Klebsiella variicola strain DX120E plasmid pKV1, complete sequence	53309-53328	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	CP008701	Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence	65265-65284	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	CP008701	Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence	65353-65372	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	CP008701	Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence	65397-65416	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP011633	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence	57616-57635	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP011633	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence	57660-57679	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP011633	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence	57704-57723	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	25885-25904	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	25929-25948	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	26017-26036	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	26151-26170	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	26283-26302	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_LR130540	Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2	162121-162140	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_LR130540	Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2	162431-162450	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	181884-181903	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	182016-182035	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	182148-182167	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	182236-182255	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	182324-182343	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	106827-106846	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	106915-106934	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	106959-106978	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	107003-107022	1.0
NZ_CP009275_1	1.14\|53309\|20\|NZ_CP009275\|CRT	53309-53328	20	NZ_CP054255	Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence	107047-107066	1.0

1. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

2. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

3. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

4. spacer 1.1|52733|20|NZ_CP009275|CRT matches to CP008701 (Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

5. spacer 1.1|52733|20|NZ_CP009275|CRT matches to CP008701 (Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

6. spacer 1.1|52733|20|NZ_CP009275|CRT matches to CP008701 (Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

7. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP011633 (Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

8. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

9. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

10. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

11. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_LR130540 (Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

12. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_LR130540 (Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

13. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

14. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

15. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

16. spacer 1.1|52733|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

cctttaccgtcagcgccgga	CRISPR spacer
cctttaccgtcagcgccgga	Protospacer
********************

17. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

18. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

19. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

20. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

21. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

22. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

23. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

24. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

25. spacer 1.12|53219|20|NZ_CP009275|CRT matches to CP008701 (Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

26. spacer 1.12|53219|20|NZ_CP009275|CRT matches to CP008701 (Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

27. spacer 1.12|53219|20|NZ_CP009275|CRT matches to CP008701 (Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

28. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP011633 (Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

29. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP011633 (Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

30. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP011633 (Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

31. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

32. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

33. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

34. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

35. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

36. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_LR130540 (Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

37. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_LR130540 (Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

38. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

39. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

40. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

41. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

42. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

43. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

44. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

45. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

46. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

47. spacer 1.12|53219|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

48. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

49. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

50. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

51. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

52. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

53. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

54. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

55. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP009275 (Klebsiella variicola strain DX120E plasmid pKV1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

56. spacer 1.14|53309|20|NZ_CP009275|CRT matches to CP008701 (Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

57. spacer 1.14|53309|20|NZ_CP009275|CRT matches to CP008701 (Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

58. spacer 1.14|53309|20|NZ_CP009275|CRT matches to CP008701 (Klebsiella variicola strain Kp5-1 plasmid pKp5-1, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

59. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP011633 (Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

60. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP011633 (Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

61. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP011633 (Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

62. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

63. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

64. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

65. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

66. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

67. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_LR130540 (Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

68. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_LR130540 (Klebsiella variicola strain AJ055 isolate AJ055 plasmid 2) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

69. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

70. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

71. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

72. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

73. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

74. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

75. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

76. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

77. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

78. spacer 1.14|53309|20|NZ_CP009275|CRT matches to NZ_CP054255 (Klebsiella variicola strain FH-1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acttcccggtcagcgccgga	CRISPR spacer
acttcccggtcagcgccgga	Protospacer
********************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

47206 : 55683

Macacine_betaherpesvirus(50.0%)

integrase

attL 44760:44773|attR 52454:52467

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
44760:44773	attL	NA	NA	NA	NA
WP_001515717.1\|47206_47947_+\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	5.4e-25	58.6
WP_032740675.1\|48729_49740_-	replication initiation protein	J9Q7H0	Salmonella_phage	8.8e-87	54.6
WP_000523815.1\|50481_51648_+	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	1.8e-224	97.7
WP_032740676.1\|51647_52613_+	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	1.2e-154	88.8
52454:52467	attR	NA	NA	NA	NA
WP_040107907.1\|53922_54312_-	fluoride efflux transporter CrcB	A0A2H4J148	uncultured_Caudovirales_phage	8.7e-27	56.0
WP_032740678.1\|54393_55683_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	5.9e-120	52.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP009276

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP009274

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP009275

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection