CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP010451	Corynebacterium glutamicum strain B253, complete genome	8 crisprs	DEDDh,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas9,WYL,PrimPol,DinG	0	37	2	0
NZ_CP010452	Corynebacterium glutamicum strain B253 plasmid, complete sequence	0 crisprs	csa3	0	0	0	0

1. NZ_CP010451

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP010451_1

• CRISPR_ID: NZ_CP010451_1
• CRISPR_location: 24754-24839
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010451_1

Consensus_repeat	Method
ACTCTCAGTTTCTACACTGAGGG	CRISPRCasFinder

spacers of NZ_CP010451_1

>1.1|24777|40|NZ_CP010451|CRISPRCasFinder
CATCACTTTCTACACTGAGGGCATCACTTTATACACTGAG

CRISPR arrays and Neighbor proteins around NZ_CP010451_1

CRISPR arrays

The CRISPR arrays of NZ_CP010451_1

>merge|NZ_CP010451|1|24754-24839|CRISPRCasFinder
ACTCTCAGTTTCTACACTGAGGGCATCACTTTCTACACTGAGGGCATCACTTTATACACTGAGACCCTCAGTTTCTACACTGAGGG

>NZ_CP010451|1|1|24754-24839|CRISPRCasFinder
ACTCTCAGTTTCTACACTGAGGG	CATCACTTTCTACACTGAGGGCATCACTTTATACACTGAG
ACCCTCAGTTTCTACACTGAGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010451.1|WP_040966682.1|24913_26194_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_040966686.1|31576_32413_-|hypothetical-protein	unknown	unknown	gnl|CDD|236766
NZ_CP010451.1|WP_003855382.1|32468_33041_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NZ_CP010451.1|WP_040966678.1|17864_18737_-|cytochrome-c-biogenesis-protein-CcdA	unknown	unknown	gnl|CDD|223856
NZ_CP010451.1|WP_040966681.1|20075_21071_+|M56-family-metallopeptidase	unknown	unknown	gnl|CDD|320685
NZ_CP010451.1|WP_031512453.1|28811_29795_+|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380535
NZ_CP010451.1|WP_011013316.1|11526_11775_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_003860996.1|14411_14756_+|DUF3566-domain-containing-protein	unknown	unknown	gnl|CDD|378809
NZ_CP010451.1|WP_003855379.1|29791_30817_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224093
NZ_CP010451.1|WP_040966685.1|28109_28769_+|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224046
NZ_CP010451.1|WP_040966675.1|15213_16251_-|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl|CDD|225411
NZ_CP010451.1|WP_040966684.1|27228_28080_-|metal-ABC-transporter-permease	unknown	unknown	gnl|CDD|224033
NZ_CP010451.1|WP_040966680.1|19707_20079_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|226207
NZ_CP010451.1|WP_003861061.1|30813_31575_+|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224053
NZ_CP010451.1|WP_040966679.1|18740_19514_-|DsbA-family-protein	unknown	unknown	gnl|CDD|224565
NZ_CP010451.1|WP_040966677.1|17267_17681_+|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NZ_CP010451.1|WP_040966687.1|33150_33810_+|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl|CDD|223777
NZ_CP010451.1|WP_011896350.1|11837_14408_+|DNA-gyrase-subunit-A	unknown	unknown	gnl|CDD|235502
NZ_CP010451.1|WP_040966676.1|16321_17218_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176112
NZ_CP010451.1|WP_040966683.1|26275_27232_-|metal-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|223874

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010451.1|WP_040966686.1|31576_32413_-|hypothetical-protein	gnl|CDD|236766	PRK10811, rne, ribonuclease E; Reviewed.	9.88847e-06
NZ_CP010451.1|WP_003855382.1|32468_33041_+|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	5.89608e-66
NZ_CP010451.1|WP_040966678.1|17864_18737_-|cytochrome-c-biogenesis-protein-CcdA	gnl|CDD|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	2.38863e-32
NZ_CP010451.1|WP_040966681.1|20075_21071_+|M56-family-metallopeptidase	gnl|CDD|320685	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	5.82841e-32
NZ_CP010451.1|WP_031512453.1|28811_29795_+|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|380535	cd06312, PBP1_ABC_sugar_binding-like, periplasmic sugar-binding domain of uncharacterized ABC-type transport systems. Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	5.36937e-83
NZ_CP010451.1|WP_003860996.1|14411_14756_+|DUF3566-domain-containing-protein	gnl|CDD|378809	pfam12089, DUF3566, Transmembrane domain of unknown function (DUF3566). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 136 to 304 amino acids in length. This region represents a transmembrane region found at the C-terminus of the proteins.	5.17781e-26
NZ_CP010451.1|WP_003855379.1|29791_30817_+|ABC-transporter-permease	gnl|CDD|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	3.80776e-63
NZ_CP010451.1|WP_040966685.1|28109_28769_+|metal-ABC-transporter-ATP-binding-protein	gnl|CDD|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	7.5996e-85
NZ_CP010451.1|WP_040966675.1|15213_16251_-|YeiH-family-putative-sulfate-export-transporter	gnl|CDD|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	8.43697e-96
NZ_CP010451.1|WP_040966684.1|27228_28080_-|metal-ABC-transporter-permease	gnl|CDD|224033	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism].	1.26055e-58
NZ_CP010451.1|WP_040966680.1|19707_20079_+|MarR-family-transcriptional-regulator	gnl|CDD|226207	COG3682, COG3682, Predicted transcriptional regulator [Transcription].	2.73032e-39
NZ_CP010451.1|WP_003861061.1|30813_31575_+|sugar-ABC-transporter-ATP-binding-protein	gnl|CDD|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	2.85564e-101
NZ_CP010451.1|WP_040966683.1|26275_27232_-|metal-ABC-transporter-substrate-binding-protein	gnl|CDD|223874	COG0803, LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism].	1.58652e-81
NZ_CP010451.1|WP_040966677.1|17267_17681_+|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	0.000545816
NZ_CP010451.1|WP_040966687.1|33150_33810_+|rhomboid-family-intramembrane-serine-protease	gnl|CDD|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	2.13542e-27
NZ_CP010451.1|WP_011896350.1|11837_14408_+|DNA-gyrase-subunit-A	gnl|CDD|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NZ_CP010451.1|WP_040966676.1|16321_17218_+|LysR-family-transcriptional-regulator	gnl|CDD|176112	cd08420, PBP2_CysL_like, C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold. CysL, also known as YwfK, is a regular of sulfur metabolism in Bacillus subtilis. Sulfur is required for the synthesis of proteins and essential cofactors in all living organism. Sulfur can be assimilated either from inorganic sources (sulfate and thiosulfate), or from organic sources (sulfate esters, sulfamates, and sulfonates). CysL activates the transcription of the cysJI operon encoding sulfite reductase, which reduces sulfite to sulfide. Both cysL mutant and cysJI mutant are unable to grow using sulfate or sulfite as the sulfur source. Like other LysR-type regulators, CysL also negatively regulates its own transcription. In Escherichia coli, three LysR-type activators are involved in the regulation of sulfur metabolism: CysB, Cbl and MetR. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.96135e-53
NZ_CP010451.1|WP_040966679.1|18740_19514_-|DsbA-family-protein	gnl|CDD|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	8.06885e-36

Protein sequences

>NZ_CP010451.1|WP_040966681.1|20075_21071_+|M56-family-metallopeptidase
MTAASALTVALIIGISLAVIGIFGPALLRHAAPALAKTPRLAVALLIGGILVWPTTLLALSLALAWVLAGPALLPQKAALVCEQCLTAANPFSVESIQTALPTVLLLAVPTVIAAMCTVGIAAQFLARVRCSRSTAARVQQEAYRRPLLGYNVSVVHDHRPWALTFSPRLGGITLSSGAIDQLADDELEAVLAHEQAHMDQRHHIVTAWVDSIAAQLRWVPFIREAAEVLPDYLEIAADQQACRKVNTTALVRALLVLGEKKIPTGTIGSAAGTLFAAGPGRIPHLVGSSTGRKGYVPALAAGSQILLLGFVSVIVLLSYAIALLTGCSLP
>NZ_CP010451.1|WP_040966680.1|19707_20079_+|MarR-family-transcriptional-regulator
MSIEPGIPTLGPLEEQVMHILWDHGNLTVREVIEFLPGDPAYTTIATVLRHLGRKGMVTTVKDGRTARHSALMNREQYTAGIMDQVLSTSRDRSASILHFVDTITATDRELLLEYLQQQEGRK
>NZ_CP010451.1|WP_040966679.1|18740_19514_-|DsbA-family-protein
MVKENSVNQQSKKWLVPTLVVIIAVLLIAVVLLMYRGNASDTTEGAAAAAPAATSDSAAASTAASGSASGTADSDLTSVEARDPSDPVAVGDVNAPVGLVVFSDYQCPFCAKWSDETLPQMMKHVEDGNLRIEWREVNIFGEPSERGARAAYAAGLQDAYLEYHNALFANGEKPSEELLSEEGLIKLAGDLGLDESKFTADFQSPETAAAIAQHQQLGIDLGAYSTPAFLLGGQPIMGAQPASVFEAAFEQALAAKE
>NZ_CP010451.1|WP_040966678.1|17864_18737_-|cytochrome-c-biogenesis-protein-CcdA
MDVGLVTAFLGGTLALLSPCAALLLPAFFASSVGAGPRMILHGVVFYAGLLVLLVPLGLGAGILGELFITQRQTIIVVSSIVLIILGFVQTFGGGFDFGKALPGLDRLQSKATVTSGLGKSFLLGMTSSIAGFCSGPILGAVLTLAATSGNSITSALILSAYGAGMVLPLMAIAALWAKLGQRGQQMLRGREFTFLGRQWHIVSVISGALIIAVGILFWSTNGLVSMPELVPMDTQIWLQEATFSLGSPLFDIAVIIVAAGLFLYCWNQRQKRKEEAQRPKESGWVINPR
>NZ_CP010451.1|WP_040966677.1|17267_17681_+|SMI1/KNR4-family-protein
MNEIPEWLTLVSVEAGKRLGLPGPLVFPPELITLAVEGIELIELEPSWTSDLPLPEFGFLAADMVDFYDDYEFSEWIPGAWPLALDGGGGFFCLDLRAANADGEIPVVWVHASNLGWGDDEAVRVAASLADLLSPSK
>NZ_CP010451.1|WP_040966676.1|16321_17218_+|LysR-family-transcriptional-regulator
MDNGWPNLQTLALFVAIVEEGSLGAGARKVGMAQPNASRAIAELEADMKAELLVRHPRGSHPTAAGLALIEHSRNLLQSVQEFTEWVTEGRTEQPLKLHVGASMTIAEALLPAWVADMRTRFPASRVDVSVMNSSQVIEAVQKGHLQLGFIETPHVPVRLHARVVQEDKLIVVISPNHEWANRTGRISLRELSETPLIVREVGSGTREALQELLADYDMAVPIQVLNSNAAVRVVVEAGAGPAVLGELALRDHLALGRLLSVPFEGSGVTRPLTAVWSGPRRLPILAGELVSIASNHI
>NZ_CP010451.1|WP_040966675.1|15213_16251_-|YeiH-family-putative-sulfate-export-transporter
MSTNLPESTPPFTQLRTGVLQKYTPGLLLCSIAVLIAMIVNHFFSGVSPLIVAIILGIILTNLVQLPASISPGITLASKKLLRLGIVFLGLQLVFSDILSLGFPMLAVIVCIVAGGIFGTILMGHLLRMKPTQVLLIACGFSICGAAAVAGVEGVTDSEEEEVVTAVALVVIFGTLMIPFIPFATKVLGLSPEIGGMWAGGSIHEIAQVVAAGGIIGGGALGAAVVVKLARVLLLAPIAAILSFRQRRQDYTSPDGKRPPVVPLFILGFLAMVVLRSTVALPDEVIAAGGFLQTTLLSAAMFGLGCDVKIQNLIHVGVKPFILAFGSTTLVTSIALAGTLLTHLG
>NZ_CP010451.1|WP_003860996.1|14411_14756_+|DUF3566-domain-containing-protein
MASREVSITRISPLATFRVALAMSIIGLVAWIICVTVLYFGLNVAGVWQNFNDVIGGVGAEQTITFGLVLSISALLGAIGAITVAVLAPLCAIIYNSIVDLFGGLQIQLQEEVD
>NZ_CP010451.1|WP_011896350.1|11837_14408_+|DNA-gyrase-subunit-A
MSDDNTGQFDRVNPIDINEEMQSSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDNGYRPDRSYVKSAKPVADTMGNFHPHGDTAIYDTLVRMAQPWSMRYPLVDGQGNFGSRGNDGPAAMRYTECRMTPLAMEMVRDIRENTVNFSPNYDGKTLEPDVLPSRVPNLLMNGSGGIAVGMATNIPPHNLNELADAIFWLLENPDAEESEALEACMKFVKGPDFPTAGLIIGDKGIHDAYTTGRGSIRMRGVTSIEEEGNRTVIVITELPYQVNPDNLISNIAEQVRDGKLVGISKIEDESSDRVGMRIVVTLKRDAVARVVLNNLFKHSQLQANFGANMLSIVDGVPRTLRLDQMLRYYVAHQIEVIVRRTQYRLDKAEERAHLLRGLVKALDMLDEVIALIRRSPTPDEARTGLMSLLDVDEAQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILASPERQRTIVRDELTEIVEKYGDERRSQIIAATGDVSEEDLIARENVVITITSTGYAKRTKVDAYKSQKRGGKGVRGAELKQDDIVRHFFVSSTHDWILFFTNYGRVYRLKAFELPEASRTARGQHVANLLEFQPGEQIAQVIQLESYNDFPYLVLATAHGRVKKSRLLDYESARSGGLIAINLNEDDRLIGAALCGEEDDLLLVSEFGQSIRFTADDEQLRPMGRATAGVKGMRFRDNDQLLSMSVVRDGEFLLVATSGGYGKRTPLEDYSTQGRGGLGVVTFKYTPKRGRLVSAIAVEEDDEIFAITSAGGVVRTEVKQIRPSSRATMGVRLVNLEEGVELLAIDKNVEDQGEASAEAVAKGAVEGPASKTAAEETDSVDNGSDENGEE
>NZ_CP010451.1|WP_011013316.1|11526_11775_-|hypothetical-protein
MPQNWYQSDTILGMAMTLRLNDAQDRALTLLARTQGCSKQEAATRAIIAAASRAVDDAEIAGLARTMLHEYAGVEKRIRQAR
>NZ_CP010451.1|WP_040966682.1|24913_26194_-|hypothetical-protein
MKNSKLLLIAAVSTASILLASCGTDSSADTATASSSATVTSEAHDHDGHEAEGSNTAVEVSFPQARIVTTYDGGIITLDANTLEVLDDTELAGFNRLNSAGDGRHVFVSTGGGFQLFDTGAWTEPHGDHTHSYTATPELTDITYSTDKPGHVVNHAGKTVLFGDGDGKIQIFDTASLLKGDEVEPEIKNALEPHHGVAVVLENGDLLHTLGDEDSRNGAVVFNAAGEEIARNEQCPGVHGESAALGDAIAVGCEDGVLIYKDSEFTKVQAPDSYGRIGNQSGSDISPVVLGDYKVDKDADLERPERVSLTNTETGELTLVDLGTSYSFRSLGRGPAGEAVVLGTDGALHIIDASTGAITNTYPVIDAWTEPEVWQEARPTLFINKDRAYVSDPSNNELHVVDLANGNILASATLPGTPNELTGVSG
>NZ_CP010451.1|WP_040966683.1|26275_27232_-|metal-ABC-transporter-substrate-binding-protein
MILKDIFNNGELFGASSAKNFRKLLAVPAVAASLAFGITACSAVDDTPDIVVTTNILGDVVSHIVGDSADVQVLMKPNADPHSFGVSVQDAAAMENADLIVANGLGLEEGLQSNVDNAKNQGVPVLEVGEHIDVIDYSPGVPDPHFWTDPARMIAATEVIEAELIKELDPSLTESIKQSAQHYREELVALDEEVTELLSSVAPENRKLVTNHNVFGYLASRFNYTVIGTIIPGGSTLAAPSASDLNDISTAIEDNNVPAIFTDTSSPQRLAEVLASNAGIDVQVVSIFTESTTDADGEAPTYISMQKINAERIASTLS
>NZ_CP010451.1|WP_040966684.1|27228_28080_-|metal-ABC-transporter-permease
MKFFIDALIVPFDVSFISRALVAGCLAAILCSLIGTWVILRRLTFFGDAMSHGMLPGVATASLLGGNLMFGTAISALIMSAGVVWTSRKSSLSQDVSIGLQFITMLSLGVVIVSHSDSHAVDLTSFLFGDILGVRPSDIFIIAIATVLGGLTIFLFHRQFTALAFDERKAHTLGLNPRFAHLLMLALIALATVVSFQVVGTLLVFGLLIGPPATAALLVQDKASISLIMIVASLLGCAEIYLGLLISWHASTAAGATITLLSAAIFFATLLTKSAISKLSFTA
>NZ_CP010451.1|WP_040966685.1|28109_28769_+|metal-ABC-transporter-ATP-binding-protein
MAELSVRNLTCTYGNHIALNNITARFPTGKITALIGSNGSGKSTLLETLAGTLAPRSGSINNLVPEIAFVPQRSHVSHNLPITIRQTVSMGRWSAKKNWQRLTAADRNIVDSCLDGLEISGLADRPLGEVSGGQRQRALIAQGLAQQAPLLLLDEPLAAVDSHAASLIEDVINQQRNQGTTIILATHDLDQAHQTDQIIALEKGIIKPQRKATESIKKR
>NZ_CP010451.1|WP_031512453.1|28811_29795_+|sugar-ABC-transporter-substrate-binding-protein
MKLPRLAAALIGAALLITGCSATGGAPRATDGASGGGTVDTPRLVVAMVSHGAPGDTFWDLVRKGAEDAAQKDNIELRYASNPEIPEQSNLVQNAIDSRVDGIAMTMPNAQSLGPVAQKAVDAGIPVVGLNAGMNEYQDYGMTGFFGQDESVAGASAGARLAEENAQKVLCVIHEQGNSSQEARCGGVSEGLGKQVETLYVNGMDLTSVNSTLQAKLAQDRSIDWVVGLQAGVSMAISDAADAANSEVKIATFDTNAQLMTAIRDGKIQFAIDQQPYLQGYMAVDSLWLAHRNGTTVGGGRPVYTGPAIVDATNVDVIAEAVGEGLR
>NZ_CP010451.1|WP_003855379.1|29791_30817_+|ABC-transporter-permease
MTKIKSGEASTSIVERALKRPELTSLLGAVLVFTLFMVVAPAFRSWDSMATVLYASSTIGIMAVAVGLLMIADEFDLSTGVAVTTAALAASMFSYNLWLNTWVGALIALVISLAIGFFNGFLVVKTKIASFLITLATFLMLQGINLAVTKLISGTVATPTIADMEGFPSARAVFASSIPIFGVNIRITVFWWLLFVIVGTFVLFKTRIGNWIFAVGGDEEAARAVGVPVRGVKIGLFMFVGFAAWFVGMHNLFLFDSIQAGQGVGNEFLYIIAAVIGGISMTGGRGTVVGTMIGALIFGMTNQGIVYAGWNPDWFMFFLGGTLLLAVLLNHRFERFNKERS
>NZ_CP010451.1|WP_003861061.1|30813_31575_+|sugar-ABC-transporter-ATP-binding-protein
MTGLIQLREVSKKYGAFQALNDINLSVRAGEVTCVLGDNGAGKSTLIKILSGLHPATSGEVIVAGDVVNFGSPRDALDAGIATVYQDLAVVGQMSVWRNFFLGQELTGRFGVLKQEEMRRITDEQLREMGIELRDVDVPVASLSGGQRQVVAIARAIYFGARVLILDEPTAALGVKQSGMVLRFIAAARDRGIGVIFITHNPHHAYLVGDHFILLNLGKQVMDKSRAEVELEELTLAMSGGGELDSLSHELKR
>NZ_CP010451.1|WP_040966686.1|31576_32413_-|hypothetical-protein
MSTIGNLKLVVDGARKAYGTYADYRDRKVSETYEALSHAAGEYAPKAEQAVETARESAKEFYAESRDKAGNVTKAARARLEKALAEADKQGTSALKDTRESGKKLNRKARRKADKAAKAARKATEKKESHWVRNLSLAALATSGIVAVAYAFLNKTKKETPGTQPPRVEAQLKKAVEQDEPEVVAEAAVEEPELVYSTESPETTEAPAEATETPAETTEEEAKTEAELEAELEAEFEAELEAEADAAQEAAEEAEAEAIQAEFDKKNAPQRTQSEKKK
>NZ_CP010451.1|WP_003855382.1|32468_33041_+|peptidylprolyl-isomerase
MGHVVGISLDVVMMGVMTSKTATAILHTNRGDITIDLFGNHAPETVANFVGLAQGTKDYQSANAQGDSEGPFYNGSVFHRVIDGFMIQGGDPTGTGRGGPGYTFADEFHPELRFDRAYLLAMANAGPGTNGSQFFITVTPTPHLNNAHTIFGEVTDAESQKVVDAIATTATDRYDRPADAVVIESVEITA
>NZ_CP010451.1|WP_040966687.1|33150_33810_+|rhomboid-family-intramembrane-serine-protease
MNVERIYRQAPASTLISLAIIAVYAVTAIQSRSVTDNLGSTSIGDAWILYAPLMDDGGFGPLRAIGGMFLHIGPGHMLLNLVLLWLLGREIERDFGSALFTAMYFVGGIGASAAVIWMDPYSPTAGASGAIYAMMAILVGLFVLRSADIRAPLILIAINIAYTLMSTNVSLWGHLGGLITGALITWPMVKAKNQRTRWIIVLIGLAVVVVAVILGIDRV

Crispr_ID: NZ_CP010451_2

• CRISPR_ID: NZ_CP010451_2
• CRISPR_location: 329919-330014
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010451_2

Consensus_repeat	Method
TGCGTGGGCAGTGTGGTTTGGTTT	CRISPRCasFinder

spacers of NZ_CP010451_2

>2.1|329943|48|NZ_CP010451|CRISPRCasFinder
TGGGGGCTCGGAACCGGTCACAGATGCCCACGATTGCGGTTTTTCCGT

CRISPR arrays and Neighbor proteins around NZ_CP010451_2

CRISPR arrays

The CRISPR arrays of NZ_CP010451_2

>merge|NZ_CP010451|2|329919-330014|CRISPRCasFinder
TGCGTGGGCAGTGTGGTTTGGTTTTGGGGGCTCGGAACCGGTCACAGATGCCCACGATTGCGGTTTTTCCGTTGCGTGGGCAGTGTGGTTTGGTCT

>NZ_CP010451|2|2|329919-330014|CRISPRCasFinder
TGCGTGGGCAGTGTGGTTTGGTTT	TGGGGGCTCGGAACCGGTCACAGATGCCCACGATTGCGGTTTTTCCGT
TGCGTGGGCAGTGTGGTTTGGTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010451.1|WP_003855827.1|337026_337227_+|DUF4244-domain-containing-protein	unknown	unknown	gnl|CDD|379429
NZ_CP010451.1|WP_003855829.1|337573_337873_+|flp-pilus-assembly-TadE/G-like-family-protein	unknown	unknown	gnl|CDD|274799
NZ_CP010451.1|WP_040966849.1|335654_336431_+|type-II-secretion-system-F-family-protein	unknown	unknown	gnl|CDD|227300
NZ_CP010451.1|WP_040966848.1|334536_335670_+|TadA-family-conjugal-transfer-associated-ATPase	unknown	unknown	gnl|CDD|200328
NZ_CP010451.1|WP_003863285.1|337230_337551_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_040966846.1|330433_331429_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP010451.1|WP_040966847.1|333478_334540_+|septum-site-determining-protein	unknown	unknown	gnl|CDD|274798
NZ_CP010451.1|WP_040966843.1|326493_327276_+|endonuclease-III	unknown	unknown	gnl|CDD|223255
NZ_CP010451.1|WP_003855817.1|331443_331995_-|phage-holin-family-protein	unknown	unknown	gnl|CDD|377816
NZ_CP010451.1|WP_040966840.1|324396_325242_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293836
NZ_CP010451.1|WP_040966842.1|326262_326448_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_003863293.1|332159_333002_-|HAD-family-hydrolase	unknown	unknown	gnl|CDD|319796
NZ_CP010451.1|WP_003855806.1|323826_324300_+|MaoC-family-dehydratase	unknown	unknown	gnl|CDD|239534
NZ_CP010451.1|WP_011013542.1|328670_329867_+|MarP-family-serine-protease	unknown	unknown	gnl|CDD|367140
NZ_CP010451.1|WP_040966839.1|322608_323805_+|glutaryl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173840
NZ_CP010451.1|WP_040966838.1|321671_322616_+|amidohydrolase	unknown	unknown	gnl|CDD|225070
NZ_CP010451.1|WP_040966844.1|327283_327844_+|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NZ_CP010451.1|WP_040966841.1|325317_326001_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP010451.1|WP_040966845.1|327836_328580_+|CoA-pyrophosphatase	unknown	unknown	gnl|CDD|239518
NZ_CP010451.1|WP_040966850.1|336427_337003_+|type-II-secretion-system-F-family-protein	unknown	unknown	gnl|CDD|224975

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010451.1|WP_003855827.1|337026_337227_+|DUF4244-domain-containing-protein	gnl|CDD|379429	pfam14029, DUF4244, Protein of unknown function (DUF4244). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 66 and 95 amino acids in length. There is a conserved EYA sequence motif.	1.21917e-15
NZ_CP010451.1|WP_003855829.1|337573_337873_+|flp-pilus-assembly-TadE/G-like-family-protein	gnl|CDD|274799	TIGR03816, tadE_like_DECH, helicase/secretion neighborhood TadE-like protein. Members of this small, highly hydrophobic protein family occur in a pilus/secretion-like region that usually is next to an uncharacterized DEAH-box helicase, in Actinobacteria. Members show sequence similarity to the TadE-like family described by pfam07811. The function is unknown. [Unknown function, General].	9.82352e-08
NZ_CP010451.1|WP_040966849.1|335654_336431_+|type-II-secretion-system-F-family-protein	gnl|CDD|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	3.17122e-66
NZ_CP010451.1|WP_040966848.1|334536_335670_+|TadA-family-conjugal-transfer-associated-ATPase	gnl|CDD|200328	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase. Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.	1.90749e-154
NZ_CP010451.1|WP_040966846.1|330433_331429_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.18625e-22
NZ_CP010451.1|WP_040966847.1|333478_334540_+|septum-site-determining-protein	gnl|CDD|274798	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein. Members of this protein family belong to the MinD/ParA family of P-loop NTPases, and in particular show homology to the CpaE family of pilus assembly proteins (see ). Nearly all members are found, not only in a gene context consistent with pilus biogenesis or a pilus-like secretion apparatus, but also near a DEAD/DEAH-box helicase, suggesting an involvement in DNA transfer activity. The model describes a clade restricted to the Actinobacteria.	1.04132e-90
NZ_CP010451.1|WP_040966843.1|326493_327276_+|endonuclease-III	gnl|CDD|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	9.64965e-107
NZ_CP010451.1|WP_040966840.1|324396_325242_+|MBL-fold-metallo-hydrolase	gnl|CDD|293836	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.31864e-64
NZ_CP010451.1|WP_003855817.1|331443_331995_-|phage-holin-family-protein	gnl|CDD|377816	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III. Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.	1.12452e-31
NZ_CP010451.1|WP_003863293.1|332159_333002_-|HAD-family-hydrolase	gnl|CDD|319796	cd02612, HAD_PGPPase, phosphatidylglycerol-phosphate phosphatase, similar to Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C. This family includes Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C, PgpC (previously named yfhB) which catalyzes the dephosphorylation of phosphatidylglycerol-phosphate (PGP) to phosphatidylglycerol (PG). This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	3.05942e-74
NZ_CP010451.1|WP_003855806.1|323826_324300_+|MaoC-family-dehydratase	gnl|CDD|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	8.09464e-81
NZ_CP010451.1|WP_011013542.1|328670_329867_+|MarP-family-serine-protease	gnl|CDD|367140	pfam02674, Colicin_V, Colicin V production protein. Colicin V production protein is required in E. Coli for colicin V production from plasmid pColV-K30. This protein is coded for in the purF operon.	1.69959e-18
NZ_CP010451.1|WP_040966839.1|322608_323805_+|glutaryl-CoA-dehydrogenase	gnl|CDD|173840	cd01151, GCD, Glutaryl-CoA dehydrogenase. Glutaryl-CoA dehydrogenase (GCD). GCD is an acyl-CoA dehydrogenase, which catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and carbon dioxide in the catabolism of lysine, hydroxylysine, and tryptophan. It uses electron transfer flavoprotein (ETF) as an electron acceptor. GCD is a homotetramer. GCD deficiency leads to a severe neurological disorder in humans.	1.41006e-107
NZ_CP010451.1|WP_040966838.1|321671_322616_+|amidohydrolase	gnl|CDD|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	3.34222e-87
NZ_CP010451.1|WP_040966844.1|327283_327844_+|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	7.25184e-23
NZ_CP010451.1|WP_040966841.1|325317_326001_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	8.3036e-56
NZ_CP010451.1|WP_040966845.1|327836_328580_+|CoA-pyrophosphatase	gnl|CDD|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	2.18903e-53
NZ_CP010451.1|WP_040966850.1|336427_337003_+|type-II-secretion-system-F-family-protein	gnl|CDD|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	1.84741e-14

Protein sequences

>NZ_CP010451.1|WP_011013542.1|328670_329867_+|MarP-family-serine-protease
MLSPSLVVDAVIVLVMAFALWGGWRQGAFTSLLSTVGVVSGLVVGAAAAPFVMGLTDSTALRFLLAIGTVVLLVGLGNLIGAHLGAAIRDNIKFRSSRTLDSGLGAIFQVLATLIVVWLVAIPLATGLPGTVASGIRDSRILGFVDKYTPQGLDTLPSKIAAMLSESGLPPLISPFTGGSSVEVDAPEINVTNVDLVEAMRPSVIHVMGDAQECSRRLMGSGFVASPDYVVTNAHVVAGTSTVSLDTMIGTRSAEVVFYDPNLDIAVLYSPDLGLDPLPWASTPLDTGDEAIVMGFPQSGPFNASPARVRERIMITGSNIYANGQHEREAYSVRGSIQSGNSGGPMTNEMGEVVGVVFGAAIDGSDTGYVLTAEEVQERIGDITALTQPVDTMQCAVS
>NZ_CP010451.1|WP_040966845.1|327836_328580_+|CoA-pyrophosphatase
MRNYPDLPHDFPGQNTELTPTKAPVWMHRLLDRIHTGRMANPLDGAETLGDTDSEKRAAVLMLFSGSETSFDLPNDASVLLTHRTPTMRSHAGQIAFPGGRIDPTDTNAVDCAFREAWEETGLDRHTATPLAQLNEVHIRATGYPVYPILGHWHTPSPVAVASPHETDEVFDAPLYDLIDPKNRLMVGWREWHGPAFRINDYIIWGFTGGLLSAILDTAGWATEWDTDRIFDLENTLSTSRNNERMR
>NZ_CP010451.1|WP_040966844.1|327283_327844_+|TlpA-family-protein-disulfide-reductase
MTSSAKWSIVGVVAILAVIVALIPQLVGGESAEEAQGETSTSKITTRPDCVASGAAGVDLPCLGGANGAGNELPTVVNLWAWWCEPCRAELPIFDEFATTHPELNVIGVHADQNAANGAALLEDLGVNLASYQDDSNLFAGTLGLPGVVPITIVVSPDGNVVDTFPQPFETIDDLETAVAGALQNA
>NZ_CP010451.1|WP_040966843.1|326493_327276_+|endonuclease-III
MGSITPQKRPRVGFHIANKGQETDIGRKRRARRINRTLTVAYPDAHCELDFTNPLELTVATILSAQCTDVRVNQVTPALFKRYPTAADYANADRTELEEFIRPTGFYRNKAASLIGLGEALVSLHDGQVPGTLEQLVELPGVGRKTANVVLGNAFGVPGITVDTHFGRLVRRLKLTDEEDPVKVEKVMNELIEKPEWTMFSHRLIFHGRRICHSRRAACGACMLAADCPSFGLEGPSDPFEAQKLIKSDDREHLLKMAGM
>NZ_CP010451.1|WP_040966842.1|326262_326448_-|hypothetical-protein
MTGLLVVIIPLLLMLFAFAMERIESSFLHSNAPQNTEVKSAKDAVGAEDLNEDDVQEASAA
>NZ_CP010451.1|WP_040966841.1|325317_326001_-|Crp/Fnr-family-transcriptional-regulator
MEGVQDILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARHAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSAVCVTEVHAATMNSDMLRNWVADHPAIAEQLLRVLARRLRRTNASLADLIFTDVPGRVAKTLLQLANRFGTQEAGALRVNHDLTQEEIAQLVGASRETVNKALATFAHRGWIRLEGKSVLIVDTEHLARRAR
>NZ_CP010451.1|WP_040966840.1|324396_325242_+|MBL-fold-metallo-hydrolase
MTKLERMEHPAYSQLRPVTPSASVVLCPNPGYSSLEGTNSWVIRAPEDPRSIVIDPGPEDEGHLNVLHSKAEEVGLILLTHRHHDHADGAQRFRQLTNAPVRAMDPSYCAGAEEIHDGEIITIDGVTPQIEVVATPGHTRDSVSYFIWSGVPHESTLEGIVSGDTIAGRHTTMISETDGDLGEYLNSLAILEERGKDIPLLPGHGPDGQDVSSFARKYIERRELRLNQIREVWETRGRDVSMKDLIDAIYDDVDPVLRGAAEQSTHVAIRYLQAQEASASN
>NZ_CP010451.1|WP_003855806.1|323826_324300_+|MaoC-family-dehydratase
MTTSTTPNTIISFEDAPTLTGQDLGFSQWRTVTQEMVNTFADATDDQQWIHTDPERAKDGPFGGAIAHGFLTLSMIIPFWGELLDVTGVTTKVNYGLDKVRFTSPVKVGSRIRMGAVVREISEVKGNGLHLVADGTIEIEGQERPAVVATFLTRFYA
>NZ_CP010451.1|WP_040966839.1|322608_323805_+|glutaryl-CoA-dehydrogenase
MRDPIQGAVIPSDLFGFAEVLTEAERAVLLETRRVLEEEVKPYINEAWDRAVFPDEIVQPLQDLQLLDPPALREAGESVRDIFTGFRNFELARCDINVGTYYNASAGLFRTACMVGGSPEQAQRLDAQIKSGEVKGVFALTEPDHGSDIAGGLATTATKDADTGEWIINGEKRWIGGASTADLIATFARDTADNQVKCFLVAPQAEGVSMEIIDRKASLRIMQNAHITYNNVRVSEDARLHNISSFKDVSECLRRMRSDVAWMAVGAQAGAYEAAVKYVRSREQFGRPIAGFQLIQEKLALMLGNLTASLGMMVKLTEQQQAGIFKEENSALAKMFTSLKLRETASWAREICGGNGIILDNDVARFHADAEAVYSYEGTHEINALIVGRAITGVSAFI
>NZ_CP010451.1|WP_040966838.1|321671_322616_+|amidohydrolase
MSNNVVKYECAVDADNIVAVDMHVHLEVDSCGHESMPADIMEASSKYFKAAERTPSADAIADIYREHKMAAVVFTIDARTQMGHLPNSIDDLVASCARNNDVLIPFGSVDPRTGEDALVEARRQVEELGVRGFKFHPSVQGFDPSAPEFYPLWELLESFGLPCVFHTGQNGMGAGLPGGRGIKLRFSNPLLLDDVAADFPNLTIIMAHPSVPWQDEANSIATHKANVFIDLSGWSPKYFPESLVRQSNNVLSKKVLFGTDFPLITPEKWLAAFANLPLKDEVRPGILKDNAVKVLGLAASTERGSQTEKAVQHA
>NZ_CP010451.1|WP_040966846.1|330433_331429_-|alpha/beta-hydrolase
MAFFSFSTSPLTRLIPGSRSKVTGAKRRLSSTIASIERSPGIIALDGPFTHDHVSVRGIRLHLAEAGSPTKPLVLLIHGAFGGWYDYREVIGPLADAGFHVAAIDLRGYGMSDKPPTGYDLRHAAGELSSVIAALGHDDALLVGSDTGASIAWAIASMYPERVRGLISLGAIHPLDMRRAIRRKPHLHVSDLSRLAPFRLPSFLHNLFHFGITSEARREIVNNTSSSYQRSNAFTETVLLRKKALSIDHTITPIIRTNRYLVGSIPSKTVSAPVWLLRTNTRRWEHLANTARTRTTGPFTTIAIPGGYELPYLENPSEFAATIAEFARTTF
>NZ_CP010451.1|WP_003855817.1|331443_331995_-|phage-holin-family-protein
MSNKDGLFTDGSSTFAPKVDSIPLSDVDTSVSGEASIGTLISNATSQMSSLFRAEVELAKTELAGEAKKAAIGGGAFSVAGVIALYSSFFFFFFVAALLSEWIKPWAAFLIVFLFMLVIAAALALFGWRKVKKMGAPKNTIQSVNQLKNLVPGQASEKLEKANKRGLYTSASFHSPGAITGDH
>NZ_CP010451.1|WP_003863293.1|332159_333002_-|HAD-family-hydrolase
MKHPDPAQKVEGTTATTPTKVAAFFDLDKTIIAMSSTYAYGREFMNSGLISPVEALQLSLAQATYMFAGHTSEQMDNTRDQLTAMIRGWEVQQVRSIAEETMHSVVTPTIYAEARELIEHHQELGHDVIIISASVKELVEPIARELGVHKTVTTVLEAHDGMYTGEVLFYCKGDAKAQSILDLAEANNYDLSLSFAYSDSFTDLPMLEAVGNPAAVNPDRALKKIALEQGWKILSFKNPEPLFQMPSTRDVGIGTGVVAGIAAVAAGSIWWMKRARRGSA
>NZ_CP010451.1|WP_040966847.1|333478_334540_+|septum-site-determining-protein
MNTTTHQAILIAVEDPVLHPEAMHVAAATGRPVIETTNLMDISRHFHRASAVLIDASMASQLVPGKRRDRVFLLDSDPGPSDWKTAMKIHAEQAMLLPAQAGELLSALGRDDKQLPVASGHVIGVAGVVGGTGASTFAAALAKRRAESATTVLIDADPSSGGIDLLLGIEDVPGARWPDVGLRRGTVQAADVLKALPSTPDEVVVLSTARSNVLDPFALSESDVSAAIDCFLSADRSVDVVVDLPHARVHPDIAERLSHLVLVIPAEVRAVAAARARYMELQQLHVSITCVLRHRGWSGLDVAEVEEILGADITAEIGSIQRLAKSVEMHGLTGSLPRVLSSACDAVLGEVAA
>NZ_CP010451.1|WP_040966848.1|334536_335670_+|TadA-family-conjugal-transfer-associated-ATPase
MTDIDLVVENVQRIIATKETPPTSAEIASLIREQAGVISNEDIVMVLRRLRSDSVGVGPLESLLALPGVTDVLVNAHDSVWIDRGQGVEKVDMDLGSEEAVRRLATRLALTCGRRLDDAQPFADGRITRDDGSVLRIHAVLAPLAESGTCISVRVLRQARLSLDDLINSGTVPEDIAPALRNIINQRRSFLVVGGTGTGKTTLLSAMLTEVPADQRIICIEDTAELHPGHPSIINLVSRQANVEGAGAVSMADLLKQSLRMRPDRIVVGEIRGAEVVDLLAAMNTGHDGGAGTIHANSISEVPARMEALAATGGLDRMALHSQLAAAVDIVLVMKHTPFGRRLAQLGVLRGNPVTTQVVWDLDHGMHEGSEEAWFMP
>NZ_CP010451.1|WP_040966849.1|335654_336431_+|type-II-secretion-system-F-family-protein
MVYALGLLSVAVLISGSRGPGARTRPPTPGNGVHLFALIALFCLATVLFIVVDAYTMIAGIIIATTLFWYLRQTHAAAQRTKQSLQLASFLSLCAGNLRAGVTMVDAMDYALDNTTPDKFLSPTLQTAARQARSGGSGPRVLIDASLPDLQRLGHLWETSERHGIPLVALIDQMRSRISSKQRHGESTRAALQGPQATAVILTVLPLAGLLMGTAMGANPLGLLTGGGIGGLLLVIGVGLDAAGFVVTHKILQSASPS
>NZ_CP010451.1|WP_040966850.1|336427_337003_+|type-II-secretion-system-F-family-protein
MITALVLAAVAMFICSPNPGVRGGLLSPKSGKSLRIRAGPKKLGNADPVDVSADIELFSACLDAGLNTRDAAQVVAHVAAKTHRELWTHVVALLSIGVSAPQAFALMAGVDGLDELANLATVSHRSGSALSDGCRNISTSLLASAGDKRTAAAERAGVFIAMPLALCFLPAFMIVGLAPVVLSLGTQLINF
>NZ_CP010451.1|WP_003855827.1|337026_337227_+|DUF4244-domain-containing-protein
MSNNLELLRLRTRAILAQDDGLTTVEYALGTLAAAALAAVLYMVVNSDAVSSAFESIISDALSARP
>NZ_CP010451.1|WP_003863285.1|337230_337551_+|hypothetical-protein
MRTKQQREPPELCSDDGSVSIEAALALSSLVIVCGLIIAAMATLAAYLAAVDAAGAAARAHAIGESFEPARGHVDMHEAGGMLTATATIPAPIGQVSASAVFPVEN
>NZ_CP010451.1|WP_003855829.1|337573_337873_+|flp-pilus-assembly-TadE/G-like-family-protein
MTIASAGVASILISLLVVLAWQAGNLVAREQAQVAADVSAVAGAYAFARGELPDAACATAKHTAEANNAQLENCATEGEDLTLTVTVRGQEAHAKAGPL

Crispr_ID: NZ_CP010451_3

• CRISPR_ID: NZ_CP010451_3
• CRISPR_location: 369534-371214
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 27 spacers
• Cas_protein_info: cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NZ_CP010451_3

Consensus_repeat	Method
GGACCATCCCCGCCTGAGCGGGGAGAAC	PILER-CR
GGACCATCCCCGCCTGAGCGGGGAGAAC	CRISPRCasFinder
GGACCATCCCCGCCTGAGCGGGGAGAAC	CRT

spacers of NZ_CP010451_3

>3.1|369562|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
TATGGTTCTTTAGTAATCCTGATTTGCTGCGCG
>3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
GGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAG
>3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
GGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAG
>3.4|369747|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
ACATCGCGATTACGCAAAGCTGCAAGCATAGTG
>3.5|369808|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
GCCACATGCGCCACCACCTCAGCCGGGGCACCA
>3.6|369869|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
TTTGGCACTCTTTCCTGTTTAGATGGTGTGGCC
>3.7|369930|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
ACGTCGACAAGCTCACATCCAAACTTTCAGGAC
>3.8|369991|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
GAGGTTAGTTTTAACCCAGAGATGGTCGAGCTTG
>3.9|370053|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
CAGCGACCAACGTTAGTAAAACCTGGGCACAGCT
>3.10|370115|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
CGGTAAAGCACCACTGTCGCATACGCATAGCAC
>3.11|370176|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
CTTACCTAGCCACCCCGCAGACACGTGCCCTTG
>3.12|370237|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
CCGAGATCCACAGGGCCGATGCTGCTCGATGTG
>3.13|370298|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
TGCTCTTCCCAGAGCGTGCCCACATCCATAGTC
>3.14|370359|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
GATGTGCACCCCAGAACCAGCTGCCTAAGATCC
>3.15|370420|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
ATGCGGTCGCTGGCTTGCTTAAACGTGACATAG
>3.16|370481|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
AAGCCCCGCGTCATTGCGGGGCTTGAAATAATG
>3.17|370542|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
TCAGCACTTCCCAGGTGAAGATTGGGACGACAG
>3.18|370603|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
ATGATCTTACAGTGCGAGCGACGCTCGGCCCCG
>3.19|370664|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
TGTTCCAAGCTGCGAAAGCATGGTTTCCAGTAG
>3.20|370725|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
TACACCCGCTAGGCCAGGTGCGGAGAAAGGTACT
>3.21|370787|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
TGATTGGTTCGATGGCCGATTCATTGACTGTGG
>3.22|370848|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
GATTGGTGGTGCTGCTCAGGCAATAGGTGGTGC
>3.23|370909|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
GCCCAGTTGCCCCGATCACCATGACCAGCGCAG
>3.24|370970|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
CCACATATAGGAGGGGCGAAGTTTAACCAGCAG
>3.25|371031|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
TTTCAGAGGAAGTGGCAGCCGATGCTGACGGAG
>3.26|371092|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT
CGGTCCCCAAAGTCCGGGGTAGTAACGACCACC
>3.27|371153|33|NZ_CP010451|CRISPRCasFinder,CRT
CGCCTTGTCGACGGCCACGGTAATGGGGGAGAC

CRISPR arrays and Neighbor proteins around NZ_CP010451_3

CRISPR arrays

The CRISPR arrays of NZ_CP010451_3

>merge|NZ_CP010451|3|369534-371214|PILER-CR,CRISPRCasFinder,CRT
GGACCATCCCCGCCTGAGCGGGGAGAACTATGGTTCTTTAGTAATCCTGATTTGCTGCGCGGGACCATCCCCGCCTGAGCGGGGAGAACGGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAGGGACCATCCCCGCCTGAGCGGGGAGAACGGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAGGGACCATCCCCGCCTGAGCGGGGAGAACACATCGCGATTACGCAAAGCTGCAAGCATAGTGGGACCATCCCCGCCTGAGCGGGGAGAACGCCACATGCGCCACCACCTCAGCCGGGGCACCAGGACCATCCCCGCCTGAGCGGGGAGAACTTTGGCACTCTTTCCTGTTTAGATGGTGTGGCCGGACCATCCCCGCCTGAGCGGGGAGAACACGTCGACAAGCTCACATCCAAACTTTCAGGACGGACCATCCCCGCCTGAGCGGGGAGAACGAGGTTAGTTTTAACCCAGAGATGGTCGAGCTTGGGACCATCCCCGCCTGAGCGGGGAGAACCAGCGACCAACGTTAGTAAAACCTGGGCACAGCTGGACGATCTCCGCCTGAGCGGGGAGAACCGGTAAAGCACCACTGTCGCATACGCATAGCACGGACCATCCCCGCCTGAGCGGGGAGAACCTTACCTAGCCACCCCGCAGACACGTGCCCTTGGGACCATCCCCGCCTGAGCGGGGAGAACCCGAGATCCACAGGGCCGATGCTGCTCGATGTGGGACCATCCCCGCCTGAGCGGGGAGAACTGCTCTTCCCAGAGCGTGCCCACATCCATAGTCGGACCATCCCCGCCTGAGCGGGGAGAACGATGTGCACCCCAGAACCAGCTGCCTAAGATCCGGACCATCCCCGCCTGAGCGGGGAGAACATGCGGTCGCTGGCTTGCTTAAACGTGACATAGGGACCACCCCCGCCTGAGCGGGGAGAACAAGCCCCGCGTCATTGCGGGGCTTGAAATAATGGGACCATCCCCGCCTGAGCGGGGAGAACTCAGCACTTCCCAGGTGAAGATTGGGACGACAGGGACCATCCCCGCCTGAGCGGGGAGAACATGATCTTACAGTGCGAGCGACGCTCGGCCCCGGGACCATCCCCGCCTGAGCGGGGAGAACTGTTCCAAGCTGCGAAAGCATGGTTTCCAGTAGGGACCATCCCCGCCTGAGCGGGGAGAACTACACCCGCTAGGCCAGGTGCGGAGAAAGGTACTGGACCATCCCCGCCTGAGCGGGGAGAACTGATTGGTTCGATGGCCGATTCATTGACTGTGGGGACCATCCCCGCCTGAGCGGGGAGAACGATTGGTGGTGCTGCTCAGGCAATAGGTGGTGCGGACCATCCCCGCCTGAGCGGGGAGAACGCCCAGTTGCCCCGATCACCATGACCAGCGCAGGGACCATCCCCGCCTGAGCGGGGAGAACCCACATATAGGAGGGGCGAAGTTTAACCAGCAGGGACCATCCCCGCCTGAGCGGGGAGAACTTTCAGAGGAAGTGGCAGCCGATGCTGACGGAGGGACCATCCCCGCCTGAGCGGGGAGAACCGGTCCCCAAAGTCCGGGGTAGTAACGACCACCGGACCATCCCCGCCTGAGCGGGGAGAACCGCCTTGTCGACGGCCACGGTAATGGGGGAGACGGACCATCCCCGCCTGAGCGGGGAGAACA

>NZ_CP010451|3|1|369534-371152|PILER-CR
GGACCATCCCCGCCTGAGCGGGGAGAAC	TATGGTTCTTTAGTAATCCTGATTTGCTGCGCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACATCGCGATTACGCAAAGCTGCAAGCATAGTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCCACATGCGCCACCACCTCAGCCGGGGCACCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTTGGCACTCTTTCCTGTTTAGATGGTGTGGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACGTCGACAAGCTCACATCCAAACTTTCAGGAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAGGTTAGTTTTAACCCAGAGATGGTCGAGCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAGCGACCAACGTTAGTAAAACCTGGGCACAGCT
GGACGATCTCCGCCTGAGCGGGGAGAAC	CGGTAAAGCACCACTGTCGCATACGCATAGCAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTTACCTAGCCACCCCGCAGACACGTGCCCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCGAGATCCACAGGGCCGATGCTGCTCGATGTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCTCTTCCCAGAGCGTGCCCACATCCATAGTC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GATGTGCACCCCAGAACCAGCTGCCTAAGATCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATGCGGTCGCTGGCTTGCTTAAACGTGACATAG
GGACCACCCCCGCCTGAGCGGGGAGAAC	AAGCCCCGCGTCATTGCGGGGCTTGAAATAATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCAGCACTTCCCAGGTGAAGATTGGGACGACAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATGATCTTACAGTGCGAGCGACGCTCGGCCCCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGTTCCAAGCTGCGAAAGCATGGTTTCCAGTAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TACACCCGCTAGGCCAGGTGCGGAGAAAGGTACT
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGATTGGTTCGATGGCCGATTCATTGACTGTGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GATTGGTGGTGCTGCTCAGGCAATAGGTGGTGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCCCAGTTGCCCCGATCACCATGACCAGCGCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCACATATAGGAGGGGCGAAGTTTAACCAGCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTTCAGAGGAAGTGGCAGCCGATGCTGACGGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGGTCCCCAAAGTCCGGGGTAGTAACGACCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC

>NZ_CP010451|3|3|369534-371214|CRISPRCasFinder
GGACCATCCCCGCCTGAGCGGGGAGAAC	TATGGTTCTTTAGTAATCCTGATTTGCTGCGCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACATCGCGATTACGCAAAGCTGCAAGCATAGTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCCACATGCGCCACCACCTCAGCCGGGGCACCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTTGGCACTCTTTCCTGTTTAGATGGTGTGGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACGTCGACAAGCTCACATCCAAACTTTCAGGAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAGGTTAGTTTTAACCCAGAGATGGTCGAGCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAGCGACCAACGTTAGTAAAACCTGGGCACAGCT
GGACGATCTCCGCCTGAGCGGGGAGAAC	CGGTAAAGCACCACTGTCGCATACGCATAGCAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTTACCTAGCCACCCCGCAGACACGTGCCCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCGAGATCCACAGGGCCGATGCTGCTCGATGTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCTCTTCCCAGAGCGTGCCCACATCCATAGTC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GATGTGCACCCCAGAACCAGCTGCCTAAGATCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATGCGGTCGCTGGCTTGCTTAAACGTGACATAG
GGACCACCCCCGCCTGAGCGGGGAGAAC	AAGCCCCGCGTCATTGCGGGGCTTGAAATAATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCAGCACTTCCCAGGTGAAGATTGGGACGACAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATGATCTTACAGTGCGAGCGACGCTCGGCCCCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGTTCCAAGCTGCGAAAGCATGGTTTCCAGTAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TACACCCGCTAGGCCAGGTGCGGAGAAAGGTACT
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGATTGGTTCGATGGCCGATTCATTGACTGTGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GATTGGTGGTGCTGCTCAGGCAATAGGTGGTGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCCCAGTTGCCCCGATCACCATGACCAGCGCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCACATATAGGAGGGGCGAAGTTTAACCAGCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTTCAGAGGAAGTGGCAGCCGATGCTGACGGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGGTCCCCAAAGTCCGGGGTAGTAACGACCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGCCTTGTCGACGGCCACGGTAATGGGGGAGAC
GGACCATCCCCGCCTGAGCGGGGAGAACA

>NZ_CP010451|3|1|369534-371213|CRT
GGACCATCCCCGCCTGAGCGGGGAGAAC	TATGGTTCTTTAGTAATCCTGATTTGCTGCGCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACATCGCGATTACGCAAAGCTGCAAGCATAGTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCCACATGCGCCACCACCTCAGCCGGGGCACCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTTGGCACTCTTTCCTGTTTAGATGGTGTGGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACGTCGACAAGCTCACATCCAAACTTTCAGGAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAGGTTAGTTTTAACCCAGAGATGGTCGAGCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAGCGACCAACGTTAGTAAAACCTGGGCACAGCT
GGACGATCTCCGCCTGAGCGGGGAGAAC	CGGTAAAGCACCACTGTCGCATACGCATAGCAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTTACCTAGCCACCCCGCAGACACGTGCCCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCGAGATCCACAGGGCCGATGCTGCTCGATGTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCTCTTCCCAGAGCGTGCCCACATCCATAGTC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GATGTGCACCCCAGAACCAGCTGCCTAAGATCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATGCGGTCGCTGGCTTGCTTAAACGTGACATAG
GGACCACCCCCGCCTGAGCGGGGAGAAC	AAGCCCCGCGTCATTGCGGGGCTTGAAATAATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCAGCACTTCCCAGGTGAAGATTGGGACGACAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATGATCTTACAGTGCGAGCGACGCTCGGCCCCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGTTCCAAGCTGCGAAAGCATGGTTTCCAGTAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TACACCCGCTAGGCCAGGTGCGGAGAAAGGTACT
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGATTGGTTCGATGGCCGATTCATTGACTGTGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GATTGGTGGTGCTGCTCAGGCAATAGGTGGTGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCCCAGTTGCCCCGATCACCATGACCAGCGCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCACATATAGGAGGGGCGAAGTTTAACCAGCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTTCAGAGGAAGTGGCAGCCGATGCTGACGGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGGTCCCCAAAGTCCGGGGTAGTAACGACCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGCCTTGTCGACGGCCACGGTAATGGGGGAGAC
GGACCATCCCCGCCTGAGCGGGGAGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010451.1|WP_040966861.1|358197_359430_+|MFS-transporter	unknown	unknown	gnl|CDD|340883
NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|182031
NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|187850
NZ_CP010451.1|WP_003863266.1|356774_357410_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293792
NZ_CP010451.1|WP_040966864.1|363064_364102_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|224137
NZ_CP010451.1|WP_040966862.1|360839_361217_-|DUF2304-domain-containing-protein	unknown	unknown	gnl|CDD|378376
NZ_CP010451.1|WP_040966863.1|362003_363026_+|hypothetical-protein	unknown	unknown	gnl|CDD|223405
NZ_CP010451.1|WP_040966866.1|375042_375303_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_003855424.1|361213_361924_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133022
NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NZ_CP010451.1|WP_003863269.1|355667_356774_+|S-(hydroxymethyl)mycothiol-dehydrogenase	unknown	unknown	gnl|CDD|132492
NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl|CDD|378189
NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
NZ_CP010451.1|WP_038582304.1|359451_360387_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187566
NZ_CP010451.1|WP_040966872.1|389649_390681_+|Abi-family-protein	unknown	unknown	gnl|CDD|377910
NZ_CP010451.1|WP_003855855.1|357439_358111_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|187776
NZ_CP010451.1|WP_040966865.1|364283_366332_+|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl|CDD|223808
NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl|CDD|378191

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	2.4e-100	331.5	5.9
NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	2.1e-63	209.5	0.0
NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	3.1e-61	201.9	0.7
NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.3e-27	90.6	0.0
NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	9.4e-42	137.6	0.0
NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	1.7e-112	371.3	4.6
NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	2.6e-106	349.3	0.0
NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	6.9e-45	147.7	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010451.1|WP_040966861.1|358197_359430_+|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.03572e-15
NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.03684e-79
NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187850	cd09719, Cas1_I-E, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.7599e-129
NZ_CP010451.1|WP_003863266.1|356774_357410_+|MBL-fold-metallo-hydrolase	gnl|CDD|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	5.51317e-46
NZ_CP010451.1|WP_040966864.1|363064_364102_+|glycosyltransferase-family-2-protein	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	3.57274e-53
NZ_CP010451.1|WP_040966862.1|360839_361217_-|DUF2304-domain-containing-protein	gnl|CDD|378376	pfam10066, DUF2304, Uncharacterized conserved protein (DUF2304). Members of this family of hypothetical archaeal proteins have no known function.	4.97196e-28
NZ_CP010451.1|WP_040966863.1|362003_363026_+|hypothetical-protein	gnl|CDD|223405	COG0328, RnhA, Ribonuclease HI [DNA replication, recombination, and repair].	1.40198e-26
NZ_CP010451.1|WP_003855424.1|361213_361924_-|glycosyltransferase-family-2-protein	gnl|CDD|133022	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.	6.2111e-44
NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.87102e-155
NZ_CP010451.1|WP_003863269.1|355667_356774_+|S-(hydroxymethyl)mycothiol-dehydrogenase	gnl|CDD|132492	TIGR03451, S-hydroxymethylmycothiol_dehydrogenase, S-(hydroxymethyl)mycothiol dehydrogenase. Members of this protein family are mycothiol-dependent formaldehyde dehydrogenase (EC 1.2.1.66). This protein is found, so far, only in the Actinobacteria (Mycobacterium sp., Streptomyces sp., Corynebacterium sp., and related species), where mycothione replaces glutathione. [Cellular processes, Detoxification].	0
NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	4.89e-74
NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.92035e-115
NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.53645e-33
NZ_CP010451.1|WP_038582304.1|359451_360387_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187566	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs. This subgroup contains UDP-N-acetylglucosamine 4-epimerase of Pseudomonas aeruginosa, WbpP, an extended SDR, that catalyzes the NAD+ dependent conversion of UDP-GlcNAc and UDPGalNA to UDP-Glc and UDP-Gal. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.34964e-117
NZ_CP010451.1|WP_040966872.1|389649_390681_+|Abi-family-protein	gnl|CDD|377910	pfam07751, Abi_2, Abi-like protein. This family, found in various bacterial species, contains sequences that are similar to the Abi group of proteins, which are involved in bacteriophage resistance mediated by abortive infection in Lactococcus species. The proteins are thought to have helix-turn-helix motifs, found in many DNA-binding proteins, allowing them to perform their function.	4.91788e-46
NZ_CP010451.1|WP_003855855.1|357439_358111_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.96274e-26
NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	7.26225e-42
NZ_CP010451.1|WP_040966865.1|364283_366332_+|bifunctional-metallophosphatase/5'-nucleotidase	gnl|CDD|223808	COG0737, UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism].	9.66953e-82
NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	5.53669e-40

Protein sequences

>NZ_CP010451.1|WP_040966865.1|364283_366332_+|bifunctional-metallophosphatase/5'-nucleotidase
MKRLSRAALAVVATTAVSFSALAVPAFADEASNVELNILGVTDFHGHIAQDLSKGEMGAAGLACYVESERAANPNTSFITVGDNIGGSPFVSSILKDAPTLTALSTIGVDASALGNHEFDAGYEDLAGRVSLDGTGLAQFPYLGANVEGGTPTPAASEVVELGGVRVAYVGSVTDETSTLVSPAGIPGITFTNDLSAVNAEADRIMAAGEADVVIALMHSPARATDAFSTNVDVVFAGHTHEERVETGPARDGKQPLVVIQGMEYGKFVSDVEISYDSTAKKITAIEAVNVDAATASGACGVPNALVTSVAGIVDAAKIASDVEGAKVVATIENSFFRGADSAGETGSNRGVESSLNNLIAEAGLQAINAQTPLNADIGVMNAGGVRADLEAGEVTFSEAFATQNFSNTYGVVDITGADFIEALEQQWKDPAADRPRLALGLSNNVQYSYNPNAAQGERITHVTINGKPIDETKTYRIAGSTFLLSGGDGFTAFTNGTDITDSGLVDIDLFNSYLAANTSVDVRANQASVGIELSGTALADDSSLIPGKELTVDLSALSYTGGEVTPTTVTVTLGAETVTVPVDNTIIPKLDTTGTATATLIVPAGVTELKIETDAGTTFTLPVVATSKPADGSSVGSSAGSLVAILGVLGALGGLLGVFLHSPQGAPFLTQLHALIDQSKP
>NZ_CP010451.1|WP_040966864.1|363064_364102_+|glycosyltransferase-family-2-protein
MSNKRIGVVIVSYGHEQDVANLVDTFADQLKTGDRVVVVDNRKPWVLKDTVGERLEKHGVEIINHDNGGFAAGCNVGAAHIVDDVDLLFFLNPDTVIDDPTLFNSLRRVDEQWAAFMPYLLLPDGTINSAGNALHISGLSWVTGLDEKPVEGSSEVTDISIASGACLAVRVEWWKRLGGMEELYFMYHEDTDFSARLLLAGGRIGLLHSAYVTHHYDYAKGDYKWIYIERNRHVLLLSVLPLPLLLMLIPQILGVNLGLWAIAAKENRVGLKVKSLRLLIRDLPAIFKLRRSTQELAELTPSQYLAKMEWRLDNPNLGNIGSNKIVATVYKTYYKLCMSILKLLA
>NZ_CP010451.1|WP_040966863.1|362003_363026_+|hypothetical-protein
MKSIDLEQLAGTQSRTYQSRKITDEMVARPVHVAIALWEVPWESAKSGKIEGWVIAVDSPRGRFVRSGQTKNGDAVNRTVSMLKSALKGVRGKAWIVTGRRQAALRAALVRENYLVTGSFAEQNRAGVKASAISRRAEQSALYKAKKIGEFAERAPRVKERQEAHWWPRLSRTQGTAGVLRLATDASTDGVFRGAMCFVASNGDYLLETQDTTASSDELELESITHALIYLKTIGATQAIIESDSKAALEAIDFILNTRPRRGRWRGITARARNRFRDAWEALIDDCVVELSRVLGHAGDPLNQAADQIAYMGMRAVIFEQKSAHPTLLKGIDKALRKAE
>NZ_CP010451.1|WP_003855424.1|361213_361924_-|glycosyltransferase-family-2-protein
MDASKNSDFKDTWLVVPCYNEATVIREVLENALKTFPNIVAVNDGSPDNSAEEIHAAGAHLVNHPVNLGQGAAIQTGIEYARKQPGAKYFVTFDADGQHQVKDVVRMVERLRAEDVDIIVGTRFGRPRQADDQVPLIKRLVLRTVVLLSPKTRRLGLTDAHNGLRVFNQKVAQEMNIRMNGMSHASEIVDQIDERGWRISEEPVDILYTEYSMSKGQSLLNGVNILADGFLARRLP
>NZ_CP010451.1|WP_040966862.1|360839_361217_-|DUF2304-domain-containing-protein
MTQTTTQIIIQILLLLATAALALYFLRNRRKARAKAWVKIGFVVFIFAAVWAVIRPDDLTQLANFVGVDRGTDLMLYALVVAFMFTTLSSYVRFREQELRYSKLARAVALQNAVLPEDSQGSDPA
>NZ_CP010451.1|WP_038582304.1|359451_360387_+|NAD-dependent-epimerase/dehydratase-family-protein
MRTVVTGGAGFIGSHLVDLLIKEGHEVVVIDNLSRGRLENLSDAEATGKLTFVEADLLDVDFNEFLGTHKPEVIFHLAAQIDVRHSVVDPLHDAETNILSTIRIADAARQHGVRKVVFTSSGGSIYGEPSEFPVDETVPVDPHSPYAASKVSGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFALRLLGGLDTKVFGDGGNTRDYVYVGDVVRAFYLASGEIGGGERFNIGTSVETSDRQLHTLVAAAAGSKDDPEYAPARLGDVPRSALSFGKAKEVLGWEPEVNIEQGVAKTVEYFRTH
>NZ_CP010451.1|WP_040966861.1|358197_359430_+|MFS-transporter
MGVSAFNMSDMVANKRAQRKVWLAVALSVFTVAWGGNEFTPLLVFYRGEGFFSNLFIDLLLVFYAIGVAVGLLAAGPLSDRYGRRAVMLPAPLIAILGSALIASGEETAILIAIGRVLSGISVGMVMTAGGSWIKELSSSRFEPGVKTSAGAKRASMSLTGGFALGPALAGVMAQWLPLPGQLAYVLHIILTLILFPLLITAPETRQSAHLKTKGSFWSDVLVPSALDKRFLFVVAPIGPWVFGAGFTAYAVLPSQLRDMVSAPVAYSALIALVTLGSGFGIQQFGPQIMGTSKTRGPILAMFVTVIGMIGAVIVVMNPHPWWALVVCMALGLSYGLCMFMGLAETQNIAPPIDMAGLTGIFYCLTYVGMVFPALMTWLNQWLSYPFMLGFGAVMATICLIIVSFSARRF
>NZ_CP010451.1|WP_003855855.1|357439_358111_+|SDR-family-oxidoreductase
MDLKLGGQVILVVGGAGTIGSEVVKLLTEEGATAVAASRSTPLSIDASDEASVRAGIDQVIAEHGRLDGLVVSSAPAAQTLSAETADDPDTVLAAIEGKAITFMKAATVALEKMREAGYGRIVALSGMNSYKTLSTAASARNAALNVVVKNLADRHAGTGITVNAISPGFVVAEPDAEVNRANGDTTVGEVAEAIAFLLSPRTASISGEIISVGHKAKGVILP
>NZ_CP010451.1|WP_003863266.1|356774_357410_+|MBL-fold-metallo-hydrolase
MAHDGLRVENIVTSGIFALDGGEWEVDNNIWVVGNDDEVFIIDAAHTAAPIIEAVGGRTVKGILCTHAHNDHITVAPELAKEFDAPIFVHPGDQMLWEETHGNLAHEDLADQQKFQIAGTELIVLNTPGHSPGSSCFYLPEANELFSGDTLFQGGPGATGRKYSSFDTIIESLKTSILDLPAETTVRTGHGDHTSVGAEAPHLEEWIKRGH
>NZ_CP010451.1|WP_003863269.1|355667_356774_+|S-(hydroxymethyl)mycothiol-dehydrogenase
MSTVVPGIVALSKGAPVEKVNVVVPDPGANDVIVKIQACGVCHTDLAYRDGDISDEFPYLLGHEAAGIVEEVGESVTHVEVGDFVILNWRAVCGECRACKKGEPKYCFNTHNASKKMTLEDGTELSPALGIGAFLEKTLVHEGQCTKVNPEEDPAAAGLLGCGIMAGLGAAVNTGDIKRGESVAVFGLGGVGMAAIAGAKIAGASKIIAVDIDEKKLEWAKEFGATHTINSSGLGGEGDASEVVAKVRELTDGFGTDVSIDAVGIMPTWQQAFYSRDHAGRMVMVGVPNLTSRVDVPAIDFYGRGGSVRPAWYGDCLPERDFPTYVDLHLQGRFPLDKFVSERIGLDDVEEAFNTMKAGDVLRSVVEI
>NZ_CP010451.1|WP_040966866.1|375042_375303_+|hypothetical-protein
MTISIPTTTEDRLCFPRDEQVLLTEAMDLLTCIESSLRVADVDTQMAVARLAELYLGADDGDHFPTVLNKITQLRDRIYIQVDQAN
>NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MITVILSSPPEKLRGHLTRWLIEVSPGVFVGRPTARVRDEIWDMIVSTLTNGRAVMTFPTRDNEQGFDIRVHRSQWEKTDFEGVTLMRHPISTAKGSMKAGWSTASQHRAARRRKAK
>NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MQSGMPPSTPMQLSRATDRISFLYLEHCTLGRDGGALTATDDKGVVHVPVAALSVLLLGPGTRLTHQAVSVVADSGCSIVWVGEEGVRYYAHGRSIARSDRLLVKQAEKVSNTRSRLAVARAMYDMRFPNEDTSSLTMQQLRGKEGARVRKIYRQNSEEYGVDWNRRMYDPDDFLSGDPINQALSAAHTCLYGLCHSVIVSLGCSPGLGFVHTGHDRSFVYDIADLYKAELSIPVAFQVVSDLNKNGRAEMSDVSSITRRAMRDAFKQLRLAERVAADLKTLLIDEETVSSEEFWADIVQLWDGNDRRVSGGTNYGDPVHFPESEK
>NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYMSRMYLNPQRRQTRELLANPQKLHAAVLSSFPPSSSETTDEGRVLWRVDQTRESVALYVVSPAIPSFEHLQEQAGWSQEQSWQSSDYTAMLNRIVKGQKYAFRLTANPVHTVTEDGVKRRKAHLTPAHQLDWLTDREEQLGASFTGEAGEITAITTKSERRVFRREKRTVTIQQVTFEGSLEVKDANKLREVLCNGIGKARGYGCGLLTLAPME
>NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MPTLLLRLSGPMQSWGVSGRFVNRSTSSSPTKSGVIGLLAAAEGRPREQSVADLVNLRFGVRTDQVGSVLRDFQTEIDWRTNKAKPLTNRYYLQDYRFLAAIEGPQEILEGLETALKNPVFPLYLGRRSCPPGERVPLKIVNENLEIALQKSDWLAADWYRKKASTSVRLPISRDLLPGESADELIRDLPESFDPKERRYELRPIKHDSVTISNEVGKKPIDHDPFSLIGGV
>NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSTFVDIHLVQLVPPSCINRDDTGSPKSAIFGGVERHRVSSQAWKRAVRNDFKDYLDSSELGERTLQAVKRVSQRIQELKEELSAEQAEAAAEEILKTAGIALEKKKKDETLPTKTGYLLFLSRAEIDALAELAIAQVEGNKPTKKQAREALQGPQAIDVALFGRMLADAPEANVDASCQVEHALSVHKATREFDYYTAVDDNADEDNAGAGMIGTQEFVSSALYRYATVNVDKLVENVGDADAAARAIEAFVRSFTVSMPTGKQNTFANRTRPDFVYVEVRNDQPVSLVNAFENPVRNEGKAVSLAAAKLAEYAVNGDAAYGTKPVDSFGMANTNVDSEELEKTFGDRWDATSFEDIIKRAGAAARTSTQEN
>NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSEKTSVSNRSAVVSHVAKKLHELEAHLSAGTSRSKADLAKLRRAVGKAPGAIPDVWGITLEDLPEQLVGKTDAPSWGETSVHNALALFALHQQGKGDSMNQRGEGLGRAVRQYILTKDPGGGFDNESPILRRFNALSTSDSVDELLWHLRNTITQLRASNVKLDFAELAGQLYDFHIPEARDRVRLAWGRQLYTAPKTTEKASES
>NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSDNTVFNLLDEPWIEVLRIDGSPDTVSIKELLENAEHYQRLAASLETVNFAILRVLLAILYRSWDSPQWRNQMAASKHWQQKWVSRSVFDSEVEDYLDELEDRFDLRHPERPFMQVADLHTSKNEWKSLDILIPDAGEVGDLFTMRTDIASLSPASAAAFLIHTNAFDYSGIKSGAVGDDRVKGGRGYPIGIGWAGWLGGTTLEGHNLLETLLLNYVPQREQAGSDEDVPVWELEDPLTSSARPGFEDNALIAKAAGPVELLTWPQRRLRLKWENDQVTGVLISNGDALGYTVQDQVETMSPWRFSDPQTTKAKRLRYMPASVQPGRAMWRTLPNLLPNQNFAKAQTKYSDNAPQSKPAKTVEWVGQLSAQGYLDPTFPIRMRMVSMEYGAQSSSYADILSDSVHLSALLLSPDGEVLRSIARLAIERTEQVDYAVRQYNSNIAFAVSGDTASDTDEVQREFFFSIDGPFREWLTKLSESKDPDALLVEWDAQLRQTARAQAEQILSKQPPSVWSGRMKDSNRITGPVALNRLQGSLNKILGENLNSKKGVEDE
>NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3
MQIVIDLEVFWAKFVEKTSEHMSLLQHSRDITSVINEVSKKLLAPASEEFLQSILGETPLHEILTLAAISHDVGKASPYFQQKVPSLSQRVTHQGYGSDVTSKEIYANPHSIISAHTLIAWFEQHRGFKLSPPDREFWFHVIAGHHGSYSEFSLPSDALLREIRIWPEWQEARFALLDKLTSEHDLDEESLHGLASIFGDRMENNMLSTSAAALITGLLISADWVASSSDNFPLTNGEPQDQDYRTEDALTRINLGNHWQPGEVTTESFLDRFSLPASATMRNVQEAVVELGHQLDKPALVILENETGSGKTEAALALAEIMAEKFGFTGLFFAQPTRVTSDAIFTRVAEWLIHSVPEDTISTVLAHGKAEFNDDFKAITTGDLTAIYDDDSSNGDSPLEATQWFRGRKTGLLASVAVGTIDQVLFAVLQSKHNVLRHLGLASKVVIIDEIHAADAYMRVYTTRLLEWLGLYGVPVIALSATLPPKTRKQLIDAYQQGASRYSGRKARIDKAPVYPRITWVDGEKSGTITPEHDGLTRTTHYSFLEGDLEEMADEALKLSVDGGCIGIICSTVSRAQELYKLVSSREEEVVLLHSRFLTSDRAILESALVKKLGRKAGASRPKKLIVVSTQIIEQGLDLDFDAMITDIAPTDLIIQRIGRVHRHQMLNDSRPDSLKVPQLKIFGTGLPDIEASAPEIQTGSKRVYRHAPLLRSIRVLADHATNTDGTITTPDDVESLVTSSYDTKKTAPEAWKDAWTAAHVEERKFETDQESRAETARIPDPLAGKLAEWTKSPSLADEQAAVAQVRDADESFEVVVVQNRMGRLFALPHIKDLEGQSVDGVMELEYRTARTLATCTVRLPEWSLTDDDLFDLEADGQESWQKSRWLKGSLPLVLDENLERALEQYILRYDEQLGLLLERKEQQ
>NZ_CP010451.1|WP_040966872.1|389649_390681_+|Abi-family-protein
MMREPAELKPFKEHDELLQMLEENGLKIPSSEIAKKELRRHGYHRLSGYRYLFREMLPFEQQNSETRTFRSKQHLAGSSFEDVIALAEFDSRLRLSIVEALADFEVRLRTAVAHTLAAKDELAHLKVDKLDRRSCLNTAKGKRETNHEVFCKEVARVTAMAIRSDDFAKHHDETYGSDLPVWAVVEHLTFGSLHYLFGFMKNEDKRTVANAFGLRHPKALEKWLYALVDLRNLSNHSARLFNRSLKRSIVIPPHTVSPGGLLKQTEEFLDRNKQEKDRLYAVVAVLAYLLKSHEFGSEWPTKFREVMLTFPYIELAEFEDPLVSPQKNMGFPEHWQGDELWLP

Crispr_ID: NZ_CP010451_4

• CRISPR_ID: NZ_CP010451_4
• CRISPR_location: 371247-372496
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 20 spacers
• Cas_protein_info: cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NZ_CP010451_4

Consensus_repeat	Method
GGACCATCCCCGCCTGAGCGGGGAGAAC	CRT
GGACCATCCCCGCCTGAGCGGGGAGAAC	PILER-CR
GGACCATCCCCGCCTGAGCGGGGAGAAC	CRISPRCasFinder

spacers of NZ_CP010451_4

>4.1|371275|33|NZ_CP010451|CRT
GAATCGGCGATACAGAGCAGCGCCACGCTCGTG
>4.2|371336|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
ACATCACATCTGGCCGAATCTTAATCAGGAGGC
>4.3|371397|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
TGAGCGCATTGGGTATCGCAGCAGGCGCGACCG
>4.4|371458|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
AGGTAAAAACAAGTGCCGATCAGGTAGACAAAC
>4.5|371519|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
GACTGTCCTGGCTGGTGTTCCGGAGGCTACTAC
>4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
TGGGGCTTGATGTGGAAGAAATTAAGGCTGAGC
>4.7|371641|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
CCTGAGGTTATGCAGCTACTTAAAGATGTGAGG
>4.8|371702|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
ATTGCTCATATGGGCGGGCAGACTGCTGCGCAG
>4.9|371763|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
ATCTGTTCACCCTTCCGGTACGCATTCCACGCC
>4.10|371824|34|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
AGCAGGCGTCCGACTTGCACGCGATTACGATCCT
>4.11|371886|34|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
ACCCTGTATATCTCGGCATTCAGCCTGCCACCCT
>4.12|371948|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
GAACCTTGGTTGCGTCCGCTTCGCCAGAAGAAC
>4.13|372009|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
TTCGACCCCTCCGCGATTAAAAGCGTCGATTCG
>4.14|372070|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
ATATTTCGGTTGGTTTGTGGTGGCCTGGTGATG
>4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
CAACGACCATCGCGAAGCTGAACGGATTCATCC
>4.16|372192|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
AACAAGAACGGCCCCCGGGAGTGCTGGAAACAC
>4.17|372253|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
CAACCTTGAGTTTATCTACCTGATCGGCACTGG
>4.18|372314|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
CGCTTTGCGATCTGGATTCGCTCTTCCTTTGCC
>4.19|372375|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
CAAAAGAACATTCGACTCCGCAGCCAACACACG
>4.20|372436|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder
CATCCCCTCACTGATGGTGTACCCGGTGAGTAG

CRISPR arrays and Neighbor proteins around NZ_CP010451_4

CRISPR arrays

The CRISPR arrays of NZ_CP010451_4

>merge|NZ_CP010451|4|371247-372496|CRT,PILER-CR,CRISPRCasFinder
GGACCATCTGGAGCCGAGACGACACGTCGAATCGGCGATACAGAGCAGCGCCACGCTCGTGGGACCATCCCCGCCTGAGCGGGGAGAACACATCACATCTGGCCGAATCTTAATCAGGAGGCGGACCATCCCCGCCTGAGCGGGGAGAACTGAGCGCATTGGGTATCGCAGCAGGCGCGACCGGGACCATCCCCGCCTGAGCGGGGAGAACAGGTAAAAACAAGTGCCGATCAGGTAGACAAACGGACCATCCCCGCCTGAGCGGGGAGAACGACTGTCCTGGCTGGTGTTCCGGAGGCTACTACGGACCATCCCCGCCTGAGCGGGGAGAACTGGGGCTTGATGTGGAAGAAATTAAGGCTGAGCGGACCATCCCCGCCTGAGCGGGGAGAACCCTGAGGTTATGCAGCTACTTAAAGATGTGAGGGGACCATCCCCGCCTGAGCGGGGAGAACATTGCTCATATGGGCGGGCAGACTGCTGCGCAGGGACCATCCCCGCCTGAGCGGGGAGAACATCTGTTCACCCTTCCGGTACGCATTCCACGCCGGACCATCCCCGCCTGAGCGGGGAGAACAGCAGGCGTCCGACTTGCACGCGATTACGATCCTGGACCATCCCCGCCTGAGCGGGGAGAACACCCTGTATATCTCGGCATTCAGCCTGCCACCCTGGACCATCCCCGCCTGAGCGGGGAGAACGAACCTTGGTTGCGTCCGCTTCGCCAGAAGAACGGACCATCCCCGCCTGAGCGGGGAGAACTTCGACCCCTCCGCGATTAAAAGCGTCGATTCGGGACCATCCCCGCCTGAGCGGGGAGAACATATTTCGGTTGGTTTGTGGTGGCCTGGTGATGGGACCATCCCCGCCTGAGCGGGGAGAACCAACGACCATCGCGAAGCTGAACGGATTCATCCGGACCATCCCCGCCTGAGCGGGGAGAACAACAAGAACGGCCCCCGGGAGTGCTGGAAACACGGACCATCCCCGCCTGAGCGGGGAGAACCAACCTTGAGTTTATCTACCTGATCGGCACTGGGGACCATCCCCGCCTGAGCGGGGAGAACCGCTTTGCGATCTGGATTCGCTCTTCCTTTGCCGGACCATCCCCGCCTGAGCGGGGAGAACCAAAAGAACATTCGACTCCGCAGCCAACACACGGGACCATCCCCGCCTGAGCGGGGAGAACCATCCCCTCACTGATGGTGTACCCGGTGAGTAGGGACCATCCCCGCCTGAGCGGGGAGAAC

>NZ_CP010451|4|2|371247-372496|CRT
GGACCATCTGGAGCCGAGACGACACGTC	GAATCGGCGATACAGAGCAGCGCCACGCTCGTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACATCACATCTGGCCGAATCTTAATCAGGAGGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAGCGCATTGGGTATCGCAGCAGGCGCGACCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGGTAAAAACAAGTGCCGATCAGGTAGACAAAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GACTGTCCTGGCTGGTGTTCCGGAGGCTACTAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGGGGCTTGATGTGGAAGAAATTAAGGCTGAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCTGAGGTTATGCAGCTACTTAAAGATGTGAGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATTGCTCATATGGGCGGGCAGACTGCTGCGCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATCTGTTCACCCTTCCGGTACGCATTCCACGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGCAGGCGTCCGACTTGCACGCGATTACGATCCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACCCTGTATATCTCGGCATTCAGCCTGCCACCCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAACCTTGGTTGCGTCCGCTTCGCCAGAAGAAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTCGACCCCTCCGCGATTAAAAGCGTCGATTCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATATTTCGGTTGGTTTGTGGTGGCCTGGTGATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAACGACCATCGCGAAGCTGAACGGATTCATCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AACAAGAACGGCCCCCGGGAGTGCTGGAAACAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAACCTTGAGTTTATCTACCTGATCGGCACTGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGCTTTGCGATCTGGATTCGCTCTTCCTTTGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAAAAGAACATTCGACTCCGCAGCCAACACACG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CATCCCCTCACTGATGGTGTACCCGGTGAGTAG
GGACCATCCCCGCCTGAGCGGGGAGAAC

>NZ_CP010451|4|2|371308-372496|PILER-CR
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACATCACATCTGGCCGAATCTTAATCAGGAGGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAGCGCATTGGGTATCGCAGCAGGCGCGACCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGGTAAAAACAAGTGCCGATCAGGTAGACAAAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GACTGTCCTGGCTGGTGTTCCGGAGGCTACTAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGGGGCTTGATGTGGAAGAAATTAAGGCTGAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCTGAGGTTATGCAGCTACTTAAAGATGTGAGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATTGCTCATATGGGCGGGCAGACTGCTGCGCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATCTGTTCACCCTTCCGGTACGCATTCCACGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGCAGGCGTCCGACTTGCACGCGATTACGATCCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACCCTGTATATCTCGGCATTCAGCCTGCCACCCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAACCTTGGTTGCGTCCGCTTCGCCAGAAGAAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTCGACCCCTCCGCGATTAAAAGCGTCGATTCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATATTTCGGTTGGTTTGTGGTGGCCTGGTGATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAACGACCATCGCGAAGCTGAACGGATTCATCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AACAAGAACGGCCCCCGGGAGTGCTGGAAACAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAACCTTGAGTTTATCTACCTGATCGGCACTGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGCTTTGCGATCTGGATTCGCTCTTCCTTTGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAAAAGAACATTCGACTCCGCAGCCAACACACG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CATCCCCTCACTGATGGTGTACCCGGTGAGTAG
GGACCATCCCCGCCTGAGCGGGGAGAAC

>NZ_CP010451|4|4|371308-372496|CRISPRCasFinder
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACATCACATCTGGCCGAATCTTAATCAGGAGGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAGCGCATTGGGTATCGCAGCAGGCGCGACCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGGTAAAAACAAGTGCCGATCAGGTAGACAAAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GACTGTCCTGGCTGGTGTTCCGGAGGCTACTAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGGGGCTTGATGTGGAAGAAATTAAGGCTGAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCTGAGGTTATGCAGCTACTTAAAGATGTGAGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATTGCTCATATGGGCGGGCAGACTGCTGCGCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATCTGTTCACCCTTCCGGTACGCATTCCACGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGCAGGCGTCCGACTTGCACGCGATTACGATCCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACCCTGTATATCTCGGCATTCAGCCTGCCACCCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAACCTTGGTTGCGTCCGCTTCGCCAGAAGAAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTCGACCCCTCCGCGATTAAAAGCGTCGATTCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATATTTCGGTTGGTTTGTGGTGGCCTGGTGATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAACGACCATCGCGAAGCTGAACGGATTCATCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AACAAGAACGGCCCCCGGGAGTGCTGGAAACAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAACCTTGAGTTTATCTACCTGATCGGCACTGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGCTTTGCGATCTGGATTCGCTCTTCCTTTGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAAAAGAACATTCGACTCCGCAGCCAACACACG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CATCCCCTCACTGATGGTGTACCCGGTGAGTAG
GGACCATCCCCGCCTGAGCGGGGAGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010451.1|WP_040966861.1|358197_359430_+|MFS-transporter	unknown	unknown	gnl|CDD|340883
NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|182031
NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|187850
NZ_CP010451.1|WP_003863266.1|356774_357410_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293792
NZ_CP010451.1|WP_040966864.1|363064_364102_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|224137
NZ_CP010451.1|WP_040966862.1|360839_361217_-|DUF2304-domain-containing-protein	unknown	unknown	gnl|CDD|378376
NZ_CP010451.1|WP_040966863.1|362003_363026_+|hypothetical-protein	unknown	unknown	gnl|CDD|223405
NZ_CP010451.1|WP_040966866.1|375042_375303_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_003855424.1|361213_361924_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133022
NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NZ_CP010451.1|WP_003863269.1|355667_356774_+|S-(hydroxymethyl)mycothiol-dehydrogenase	unknown	unknown	gnl|CDD|132492
NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl|CDD|378189
NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
NZ_CP010451.1|WP_038582304.1|359451_360387_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187566
NZ_CP010451.1|WP_040966872.1|389649_390681_+|Abi-family-protein	unknown	unknown	gnl|CDD|377910
NZ_CP010451.1|WP_003855855.1|357439_358111_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|187776
NZ_CP010451.1|WP_040966865.1|364283_366332_+|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl|CDD|223808
NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl|CDD|378191

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	2.4e-100	331.5	5.9
NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	2.1e-63	209.5	0.0
NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	3.1e-61	201.9	0.7
NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.3e-27	90.6	0.0
NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	9.4e-42	137.6	0.0
NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	1.7e-112	371.3	4.6
NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	2.6e-106	349.3	0.0
NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	6.9e-45	147.7	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010451.1|WP_040966861.1|358197_359430_+|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.03572e-15
NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.03684e-79
NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187850	cd09719, Cas1_I-E, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.7599e-129
NZ_CP010451.1|WP_003863266.1|356774_357410_+|MBL-fold-metallo-hydrolase	gnl|CDD|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	5.51317e-46
NZ_CP010451.1|WP_040966864.1|363064_364102_+|glycosyltransferase-family-2-protein	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	3.57274e-53
NZ_CP010451.1|WP_040966862.1|360839_361217_-|DUF2304-domain-containing-protein	gnl|CDD|378376	pfam10066, DUF2304, Uncharacterized conserved protein (DUF2304). Members of this family of hypothetical archaeal proteins have no known function.	4.97196e-28
NZ_CP010451.1|WP_040966863.1|362003_363026_+|hypothetical-protein	gnl|CDD|223405	COG0328, RnhA, Ribonuclease HI [DNA replication, recombination, and repair].	1.40198e-26
NZ_CP010451.1|WP_003855424.1|361213_361924_-|glycosyltransferase-family-2-protein	gnl|CDD|133022	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.	6.2111e-44
NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.87102e-155
NZ_CP010451.1|WP_003863269.1|355667_356774_+|S-(hydroxymethyl)mycothiol-dehydrogenase	gnl|CDD|132492	TIGR03451, S-hydroxymethylmycothiol_dehydrogenase, S-(hydroxymethyl)mycothiol dehydrogenase. Members of this protein family are mycothiol-dependent formaldehyde dehydrogenase (EC 1.2.1.66). This protein is found, so far, only in the Actinobacteria (Mycobacterium sp., Streptomyces sp., Corynebacterium sp., and related species), where mycothione replaces glutathione. [Cellular processes, Detoxification].	0
NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	4.89e-74
NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.92035e-115
NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.53645e-33
NZ_CP010451.1|WP_038582304.1|359451_360387_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187566	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs. This subgroup contains UDP-N-acetylglucosamine 4-epimerase of Pseudomonas aeruginosa, WbpP, an extended SDR, that catalyzes the NAD+ dependent conversion of UDP-GlcNAc and UDPGalNA to UDP-Glc and UDP-Gal. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.34964e-117
NZ_CP010451.1|WP_040966872.1|389649_390681_+|Abi-family-protein	gnl|CDD|377910	pfam07751, Abi_2, Abi-like protein. This family, found in various bacterial species, contains sequences that are similar to the Abi group of proteins, which are involved in bacteriophage resistance mediated by abortive infection in Lactococcus species. The proteins are thought to have helix-turn-helix motifs, found in many DNA-binding proteins, allowing them to perform their function.	4.91788e-46
NZ_CP010451.1|WP_003855855.1|357439_358111_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.96274e-26
NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	7.26225e-42
NZ_CP010451.1|WP_040966865.1|364283_366332_+|bifunctional-metallophosphatase/5'-nucleotidase	gnl|CDD|223808	COG0737, UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism].	9.66953e-82
NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	5.53669e-40

Protein sequences

>NZ_CP010451.1|WP_040966865.1|364283_366332_+|bifunctional-metallophosphatase/5'-nucleotidase
MKRLSRAALAVVATTAVSFSALAVPAFADEASNVELNILGVTDFHGHIAQDLSKGEMGAAGLACYVESERAANPNTSFITVGDNIGGSPFVSSILKDAPTLTALSTIGVDASALGNHEFDAGYEDLAGRVSLDGTGLAQFPYLGANVEGGTPTPAASEVVELGGVRVAYVGSVTDETSTLVSPAGIPGITFTNDLSAVNAEADRIMAAGEADVVIALMHSPARATDAFSTNVDVVFAGHTHEERVETGPARDGKQPLVVIQGMEYGKFVSDVEISYDSTAKKITAIEAVNVDAATASGACGVPNALVTSVAGIVDAAKIASDVEGAKVVATIENSFFRGADSAGETGSNRGVESSLNNLIAEAGLQAINAQTPLNADIGVMNAGGVRADLEAGEVTFSEAFATQNFSNTYGVVDITGADFIEALEQQWKDPAADRPRLALGLSNNVQYSYNPNAAQGERITHVTINGKPIDETKTYRIAGSTFLLSGGDGFTAFTNGTDITDSGLVDIDLFNSYLAANTSVDVRANQASVGIELSGTALADDSSLIPGKELTVDLSALSYTGGEVTPTTVTVTLGAETVTVPVDNTIIPKLDTTGTATATLIVPAGVTELKIETDAGTTFTLPVVATSKPADGSSVGSSAGSLVAILGVLGALGGLLGVFLHSPQGAPFLTQLHALIDQSKP
>NZ_CP010451.1|WP_040966864.1|363064_364102_+|glycosyltransferase-family-2-protein
MSNKRIGVVIVSYGHEQDVANLVDTFADQLKTGDRVVVVDNRKPWVLKDTVGERLEKHGVEIINHDNGGFAAGCNVGAAHIVDDVDLLFFLNPDTVIDDPTLFNSLRRVDEQWAAFMPYLLLPDGTINSAGNALHISGLSWVTGLDEKPVEGSSEVTDISIASGACLAVRVEWWKRLGGMEELYFMYHEDTDFSARLLLAGGRIGLLHSAYVTHHYDYAKGDYKWIYIERNRHVLLLSVLPLPLLLMLIPQILGVNLGLWAIAAKENRVGLKVKSLRLLIRDLPAIFKLRRSTQELAELTPSQYLAKMEWRLDNPNLGNIGSNKIVATVYKTYYKLCMSILKLLA
>NZ_CP010451.1|WP_040966863.1|362003_363026_+|hypothetical-protein
MKSIDLEQLAGTQSRTYQSRKITDEMVARPVHVAIALWEVPWESAKSGKIEGWVIAVDSPRGRFVRSGQTKNGDAVNRTVSMLKSALKGVRGKAWIVTGRRQAALRAALVRENYLVTGSFAEQNRAGVKASAISRRAEQSALYKAKKIGEFAERAPRVKERQEAHWWPRLSRTQGTAGVLRLATDASTDGVFRGAMCFVASNGDYLLETQDTTASSDELELESITHALIYLKTIGATQAIIESDSKAALEAIDFILNTRPRRGRWRGITARARNRFRDAWEALIDDCVVELSRVLGHAGDPLNQAADQIAYMGMRAVIFEQKSAHPTLLKGIDKALRKAE
>NZ_CP010451.1|WP_003855424.1|361213_361924_-|glycosyltransferase-family-2-protein
MDASKNSDFKDTWLVVPCYNEATVIREVLENALKTFPNIVAVNDGSPDNSAEEIHAAGAHLVNHPVNLGQGAAIQTGIEYARKQPGAKYFVTFDADGQHQVKDVVRMVERLRAEDVDIIVGTRFGRPRQADDQVPLIKRLVLRTVVLLSPKTRRLGLTDAHNGLRVFNQKVAQEMNIRMNGMSHASEIVDQIDERGWRISEEPVDILYTEYSMSKGQSLLNGVNILADGFLARRLP
>NZ_CP010451.1|WP_040966862.1|360839_361217_-|DUF2304-domain-containing-protein
MTQTTTQIIIQILLLLATAALALYFLRNRRKARAKAWVKIGFVVFIFAAVWAVIRPDDLTQLANFVGVDRGTDLMLYALVVAFMFTTLSSYVRFREQELRYSKLARAVALQNAVLPEDSQGSDPA
>NZ_CP010451.1|WP_038582304.1|359451_360387_+|NAD-dependent-epimerase/dehydratase-family-protein
MRTVVTGGAGFIGSHLVDLLIKEGHEVVVIDNLSRGRLENLSDAEATGKLTFVEADLLDVDFNEFLGTHKPEVIFHLAAQIDVRHSVVDPLHDAETNILSTIRIADAARQHGVRKVVFTSSGGSIYGEPSEFPVDETVPVDPHSPYAASKVSGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFALRLLGGLDTKVFGDGGNTRDYVYVGDVVRAFYLASGEIGGGERFNIGTSVETSDRQLHTLVAAAAGSKDDPEYAPARLGDVPRSALSFGKAKEVLGWEPEVNIEQGVAKTVEYFRTH
>NZ_CP010451.1|WP_040966861.1|358197_359430_+|MFS-transporter
MGVSAFNMSDMVANKRAQRKVWLAVALSVFTVAWGGNEFTPLLVFYRGEGFFSNLFIDLLLVFYAIGVAVGLLAAGPLSDRYGRRAVMLPAPLIAILGSALIASGEETAILIAIGRVLSGISVGMVMTAGGSWIKELSSSRFEPGVKTSAGAKRASMSLTGGFALGPALAGVMAQWLPLPGQLAYVLHIILTLILFPLLITAPETRQSAHLKTKGSFWSDVLVPSALDKRFLFVVAPIGPWVFGAGFTAYAVLPSQLRDMVSAPVAYSALIALVTLGSGFGIQQFGPQIMGTSKTRGPILAMFVTVIGMIGAVIVVMNPHPWWALVVCMALGLSYGLCMFMGLAETQNIAPPIDMAGLTGIFYCLTYVGMVFPALMTWLNQWLSYPFMLGFGAVMATICLIIVSFSARRF
>NZ_CP010451.1|WP_003855855.1|357439_358111_+|SDR-family-oxidoreductase
MDLKLGGQVILVVGGAGTIGSEVVKLLTEEGATAVAASRSTPLSIDASDEASVRAGIDQVIAEHGRLDGLVVSSAPAAQTLSAETADDPDTVLAAIEGKAITFMKAATVALEKMREAGYGRIVALSGMNSYKTLSTAASARNAALNVVVKNLADRHAGTGITVNAISPGFVVAEPDAEVNRANGDTTVGEVAEAIAFLLSPRTASISGEIISVGHKAKGVILP
>NZ_CP010451.1|WP_003863266.1|356774_357410_+|MBL-fold-metallo-hydrolase
MAHDGLRVENIVTSGIFALDGGEWEVDNNIWVVGNDDEVFIIDAAHTAAPIIEAVGGRTVKGILCTHAHNDHITVAPELAKEFDAPIFVHPGDQMLWEETHGNLAHEDLADQQKFQIAGTELIVLNTPGHSPGSSCFYLPEANELFSGDTLFQGGPGATGRKYSSFDTIIESLKTSILDLPAETTVRTGHGDHTSVGAEAPHLEEWIKRGH
>NZ_CP010451.1|WP_003863269.1|355667_356774_+|S-(hydroxymethyl)mycothiol-dehydrogenase
MSTVVPGIVALSKGAPVEKVNVVVPDPGANDVIVKIQACGVCHTDLAYRDGDISDEFPYLLGHEAAGIVEEVGESVTHVEVGDFVILNWRAVCGECRACKKGEPKYCFNTHNASKKMTLEDGTELSPALGIGAFLEKTLVHEGQCTKVNPEEDPAAAGLLGCGIMAGLGAAVNTGDIKRGESVAVFGLGGVGMAAIAGAKIAGASKIIAVDIDEKKLEWAKEFGATHTINSSGLGGEGDASEVVAKVRELTDGFGTDVSIDAVGIMPTWQQAFYSRDHAGRMVMVGVPNLTSRVDVPAIDFYGRGGSVRPAWYGDCLPERDFPTYVDLHLQGRFPLDKFVSERIGLDDVEEAFNTMKAGDVLRSVVEI
>NZ_CP010451.1|WP_040966866.1|375042_375303_+|hypothetical-protein
MTISIPTTTEDRLCFPRDEQVLLTEAMDLLTCIESSLRVADVDTQMAVARLAELYLGADDGDHFPTVLNKITQLRDRIYIQVDQAN
>NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MITVILSSPPEKLRGHLTRWLIEVSPGVFVGRPTARVRDEIWDMIVSTLTNGRAVMTFPTRDNEQGFDIRVHRSQWEKTDFEGVTLMRHPISTAKGSMKAGWSTASQHRAARRRKAK
>NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MQSGMPPSTPMQLSRATDRISFLYLEHCTLGRDGGALTATDDKGVVHVPVAALSVLLLGPGTRLTHQAVSVVADSGCSIVWVGEEGVRYYAHGRSIARSDRLLVKQAEKVSNTRSRLAVARAMYDMRFPNEDTSSLTMQQLRGKEGARVRKIYRQNSEEYGVDWNRRMYDPDDFLSGDPINQALSAAHTCLYGLCHSVIVSLGCSPGLGFVHTGHDRSFVYDIADLYKAELSIPVAFQVVSDLNKNGRAEMSDVSSITRRAMRDAFKQLRLAERVAADLKTLLIDEETVSSEEFWADIVQLWDGNDRRVSGGTNYGDPVHFPESEK
>NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYMSRMYLNPQRRQTRELLANPQKLHAAVLSSFPPSSSETTDEGRVLWRVDQTRESVALYVVSPAIPSFEHLQEQAGWSQEQSWQSSDYTAMLNRIVKGQKYAFRLTANPVHTVTEDGVKRRKAHLTPAHQLDWLTDREEQLGASFTGEAGEITAITTKSERRVFRREKRTVTIQQVTFEGSLEVKDANKLREVLCNGIGKARGYGCGLLTLAPME
>NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MPTLLLRLSGPMQSWGVSGRFVNRSTSSSPTKSGVIGLLAAAEGRPREQSVADLVNLRFGVRTDQVGSVLRDFQTEIDWRTNKAKPLTNRYYLQDYRFLAAIEGPQEILEGLETALKNPVFPLYLGRRSCPPGERVPLKIVNENLEIALQKSDWLAADWYRKKASTSVRLPISRDLLPGESADELIRDLPESFDPKERRYELRPIKHDSVTISNEVGKKPIDHDPFSLIGGV
>NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSTFVDIHLVQLVPPSCINRDDTGSPKSAIFGGVERHRVSSQAWKRAVRNDFKDYLDSSELGERTLQAVKRVSQRIQELKEELSAEQAEAAAEEILKTAGIALEKKKKDETLPTKTGYLLFLSRAEIDALAELAIAQVEGNKPTKKQAREALQGPQAIDVALFGRMLADAPEANVDASCQVEHALSVHKATREFDYYTAVDDNADEDNAGAGMIGTQEFVSSALYRYATVNVDKLVENVGDADAAARAIEAFVRSFTVSMPTGKQNTFANRTRPDFVYVEVRNDQPVSLVNAFENPVRNEGKAVSLAAAKLAEYAVNGDAAYGTKPVDSFGMANTNVDSEELEKTFGDRWDATSFEDIIKRAGAAARTSTQEN
>NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSEKTSVSNRSAVVSHVAKKLHELEAHLSAGTSRSKADLAKLRRAVGKAPGAIPDVWGITLEDLPEQLVGKTDAPSWGETSVHNALALFALHQQGKGDSMNQRGEGLGRAVRQYILTKDPGGGFDNESPILRRFNALSTSDSVDELLWHLRNTITQLRASNVKLDFAELAGQLYDFHIPEARDRVRLAWGRQLYTAPKTTEKASES
>NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSDNTVFNLLDEPWIEVLRIDGSPDTVSIKELLENAEHYQRLAASLETVNFAILRVLLAILYRSWDSPQWRNQMAASKHWQQKWVSRSVFDSEVEDYLDELEDRFDLRHPERPFMQVADLHTSKNEWKSLDILIPDAGEVGDLFTMRTDIASLSPASAAAFLIHTNAFDYSGIKSGAVGDDRVKGGRGYPIGIGWAGWLGGTTLEGHNLLETLLLNYVPQREQAGSDEDVPVWELEDPLTSSARPGFEDNALIAKAAGPVELLTWPQRRLRLKWENDQVTGVLISNGDALGYTVQDQVETMSPWRFSDPQTTKAKRLRYMPASVQPGRAMWRTLPNLLPNQNFAKAQTKYSDNAPQSKPAKTVEWVGQLSAQGYLDPTFPIRMRMVSMEYGAQSSSYADILSDSVHLSALLLSPDGEVLRSIARLAIERTEQVDYAVRQYNSNIAFAVSGDTASDTDEVQREFFFSIDGPFREWLTKLSESKDPDALLVEWDAQLRQTARAQAEQILSKQPPSVWSGRMKDSNRITGPVALNRLQGSLNKILGENLNSKKGVEDE
>NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3
MQIVIDLEVFWAKFVEKTSEHMSLLQHSRDITSVINEVSKKLLAPASEEFLQSILGETPLHEILTLAAISHDVGKASPYFQQKVPSLSQRVTHQGYGSDVTSKEIYANPHSIISAHTLIAWFEQHRGFKLSPPDREFWFHVIAGHHGSYSEFSLPSDALLREIRIWPEWQEARFALLDKLTSEHDLDEESLHGLASIFGDRMENNMLSTSAAALITGLLISADWVASSSDNFPLTNGEPQDQDYRTEDALTRINLGNHWQPGEVTTESFLDRFSLPASATMRNVQEAVVELGHQLDKPALVILENETGSGKTEAALALAEIMAEKFGFTGLFFAQPTRVTSDAIFTRVAEWLIHSVPEDTISTVLAHGKAEFNDDFKAITTGDLTAIYDDDSSNGDSPLEATQWFRGRKTGLLASVAVGTIDQVLFAVLQSKHNVLRHLGLASKVVIIDEIHAADAYMRVYTTRLLEWLGLYGVPVIALSATLPPKTRKQLIDAYQQGASRYSGRKARIDKAPVYPRITWVDGEKSGTITPEHDGLTRTTHYSFLEGDLEEMADEALKLSVDGGCIGIICSTVSRAQELYKLVSSREEEVVLLHSRFLTSDRAILESALVKKLGRKAGASRPKKLIVVSTQIIEQGLDLDFDAMITDIAPTDLIIQRIGRVHRHQMLNDSRPDSLKVPQLKIFGTGLPDIEASAPEIQTGSKRVYRHAPLLRSIRVLADHATNTDGTITTPDDVESLVTSSYDTKKTAPEAWKDAWTAAHVEERKFETDQESRAETARIPDPLAGKLAEWTKSPSLADEQAAVAQVRDADESFEVVVVQNRMGRLFALPHIKDLEGQSVDGVMELEYRTARTLATCTVRLPEWSLTDDDLFDLEADGQESWQKSRWLKGSLPLVLDENLERALEQYILRYDEQLGLLLERKEQQ
>NZ_CP010451.1|WP_040966872.1|389649_390681_+|Abi-family-protein
MMREPAELKPFKEHDELLQMLEENGLKIPSSEIAKKELRRHGYHRLSGYRYLFREMLPFEQQNSETRTFRSKQHLAGSSFEDVIALAEFDSRLRLSIVEALADFEVRLRTAVAHTLAAKDELAHLKVDKLDRRSCLNTAKGKRETNHEVFCKEVARVTAMAIRSDDFAKHHDETYGSDLPVWAVVEHLTFGSLHYLFGFMKNEDKRTVANAFGLRHPKALEKWLYALVDLRNLSNHSARLFNRSLKRSIVIPPHTVSPGGLLKQTEEFLDRNKQEKDRLYAVVAVLAYLLKSHEFGSEWPTKFREVMLTFPYIELAEFEDPLVSPQKNMGFPEHWQGDELWLP

Crispr_ID: NZ_CP010451_5

• CRISPR_ID: NZ_CP010451_5
• CRISPR_location: 375420-380208
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 78 spacers
• Cas_protein_info: cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NZ_CP010451_5

Consensus_repeat	Method
GGACCATCCCCGCCTGAGCGGGGAGAAC	CRISPRCasFinder
GGACCATCCCCGCCTGAGCGGGGAGAAC	CRT
GGACCATCCCCGCCTGAGCGGGGAGAAC	PILER-CR

spacers of NZ_CP010451_5

>5.1|375448|33|NZ_CP010451|CRISPRCasFinder,CRT
GCTGATGAGCCGGGCGCTTGGATTGACATCGAT
>5.2|375509|33|NZ_CP010451|CRISPRCasFinder,CRT
AAGAGGTGCGTAACCGTCAGCGGGATGAGGAAC
>5.3|375570|33|NZ_CP010451|CRISPRCasFinder,CRT
ACCCCAGACCAGCTGCCTGCAGCCCATGGATCA
>5.4|375631|33|NZ_CP010451|CRISPRCasFinder,CRT
GCTGTCAATGAGGTCACGACGATCGCGATTACG
>5.5|375692|33|NZ_CP010451|CRISPRCasFinder,CRT
TGGTTGTATTTTTGCTGCGCCTCCAAGAAAGCC
>5.6|375753|33|NZ_CP010451|CRISPRCasFinder,CRT
CCGCATCCAAAGCTTCCTGAGCCGAATACCACG
>5.7|375814|33|NZ_CP010451|CRISPRCasFinder,CRT
GCGGTAACCCATGAGACGCTCAGGGGCATCCGG
>5.8|375875|33|NZ_CP010451|CRISPRCasFinder,CRT
GAGAAGGTGGAGACCATCGAAATCGACGTCACC
>5.9|375936|33|NZ_CP010451|CRISPRCasFinder,CRT
GAATCAGCATTGGGTTTTCATGTGGTCGCCAAC
>5.10|375997|33|NZ_CP010451|CRISPRCasFinder,CRT
GTTTTCCTGTGTTAGCGATGGCACCTCTTCGCC
>5.11|376058|33|NZ_CP010451|CRISPRCasFinder,CRT
TAAGCCCGCTGATGATCAAGCAAATACTTGTAC
>5.12|376119|33|NZ_CP010451|CRISPRCasFinder,CRT
AAGGGGCAGGTGCAATCCCTTGCCGGTGACGCG
>5.13|376180|33|NZ_CP010451|CRISPRCasFinder,CRT
TGAGGCCATATTTCAGAGATGTTGTCTTAGATG
>5.14|376241|33|NZ_CP010451|CRISPRCasFinder,CRT
TGCCGCAGCGCTAGACACAATGGCATGCGCTAC
>5.15|376302|33|NZ_CP010451|CRISPRCasFinder,CRT
TTGCTCTTGCGGAGGACATCGTCCAGGTTTGAG
>5.16|376363|33|NZ_CP010451|CRISPRCasFinder,CRT
GCTTGAGTGGGATATTGTTACCGGCGCTCTCAC
>5.17|376424|33|NZ_CP010451|CRISPRCasFinder,CRT
TGAAGCCCCGCTGGTGGGCGGGGCTTGAAGTAG
>5.18|376485|33|NZ_CP010451|CRISPRCasFinder,CRT
ACACTCATCTCCGCATAGGTGTCCAACCCCCAC
>5.19|376546|33|NZ_CP010451|CRISPRCasFinder,CRT
ACTCAGGCCACCACTCGGGCACTGAATCGGCGG
>5.20|376607|33|NZ_CP010451|CRISPRCasFinder,CRT
ACTCAGTGTCAAAATCACCAAAACTGCTATTAC
>5.21|376668|33|NZ_CP010451|CRISPRCasFinder,CRT
GGTGCAACGCTTCAAGAACCGCCGATGATTGAG
>5.22|376729|33|NZ_CP010451|CRISPRCasFinder,CRT
ACGGCACCCACACCCAGTCGTACCACACGGTCG
>5.23|376790|33|NZ_CP010451|CRISPRCasFinder,CRT
TGCTGCACATGGCCCACGGTCGTGGTCGCAGCA
>5.24|376851|33|NZ_CP010451|CRISPRCasFinder,CRT
CCCTCCACTGAGAGCGTAGATCCAGTGGAGAGC
>5.25|376912|33|NZ_CP010451|CRISPRCasFinder,CRT
TTGCTCTTGCGGAGGACATCGTCCAGGTTTGAG
>5.26|376973|33|NZ_CP010451|CRISPRCasFinder,CRT
GGCATCCAGGTGTGCTCCACCCGGTACACCGCG
>5.27|377034|33|NZ_CP010451|CRISPRCasFinder,CRT
ATGTGCCGCCCACTATTAAAGGTGCAACCAACA
>5.28|377095|33|NZ_CP010451|CRISPRCasFinder,CRT
AAAGGGAGATCGCTGATTACTTGTCTGAGCAGC
>5.29|377156|33|NZ_CP010451|CRISPRCasFinder,CRT
GCGATTGATAAAACAGGTGATGCTGTAGCTGAA
>5.30|377217|34|NZ_CP010451|CRISPRCasFinder,CRT
GAGTCGAACCTCCAAGCTATTGCTTGAGTCGGTT
>5.31|377279|33|NZ_CP010451|CRISPRCasFinder,CRT
AGCTAGATCCAAGCACAACTGGTTCCGATATTA
>5.32|377340|33|NZ_CP010451|CRISPRCasFinder,CRT
TGAGGAGTCCCGCCGTGGCCGGTAAAAGCGCCG
>5.33|377401|33|NZ_CP010451|CRISPRCasFinder,CRT
CCGACTTTAAGCGCAACGAAGCCCTCAACGACG
>5.34|377462|33|NZ_CP010451|CRISPRCasFinder,CRT
GGGGAACCACTGGATGGTTCCTGCGGTAGGCGG
>5.35|377523|33|NZ_CP010451|CRISPRCasFinder,CRT
TGCAGGGCAAGCGCACCGACGGAGTGCATTGGG
>5.36|377584|33|NZ_CP010451|CRISPRCasFinder,CRT
TGAATCCTTACCACGAGGCCATGCAGCAATCGG
>5.37|377645|33|NZ_CP010451|CRISPRCasFinder,CRT
CGGAGGGTAAGACGAAAGTGTCTAATATTCTTG
>5.38|377706|33|NZ_CP010451|CRISPRCasFinder,CRT
TAAGCAAAAAGATTACGAGCTTTCCCGCTTCGC
>5.39|377767|33|NZ_CP010451|CRISPRCasFinder,CRT
GTGGTCAAATCCATTAGTGTCTCCTAAATTGGG
>5.40|377828|33|NZ_CP010451|CRISPRCasFinder,CRT
AAGGTGTCGGTATTGAACCACACTCCGCTGGCC
>5.41|377889|33|NZ_CP010451|CRISPRCasFinder,CRT
ATACCCACTAGCGTTTGCAAGTCTTTACCGTCA
>5.42|377950|33|NZ_CP010451|CRISPRCasFinder,CRT
GGCATGGCACAAGAGGATCGACAGGAAGCCGCA
>5.43|378011|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GGGGAACCTGTACCAAATCCGTTTCCACCTGCC
>5.44|378072|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GTGTCACCCGCCTCAAGAACGATGGTGCCGGAC
>5.45|378133|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
CAGACTGGCCGAATCCAGATCGATGACCTTGGG
>5.46|378194|34|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GTCAGCGGCTTCCTCAACGTCGGTTGCCAAACCG
>5.47|378256|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
TTCTGAGCAGCCTGAACCGCCAACGAACCCTTG
>5.48|378317|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
ATAATGAGTTACATGAACAACCACAAACAATGG
>5.49|378378|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
TCGTCTTATGGGCGTTGGCAGGACACTATGGCG
>5.50|378439|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
TCTTCGCCTTGGCGTACCCCTCCTTGTATTCGG
>5.51|378500|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
TATTCGGGTTCCCGGTGGTGGAACCCAACCATG
>5.52|378561|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
TGCAGGCGCGTTCTGGTTCTGCTGCATGCGCTG
>5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GGCTCGGTGAGCTTCACGCGATCCTGTTTGCGG
>5.54|378683|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
ATTCGCCATCTTTGGCGTGATCCGGGCGGGCGG
>5.55|378744|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GGAATCCGGTCACTTGGATCCACAAGCAATACC
>5.56|378805|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GGGCCAAAACCGCTAGTCAGCGTGTATGAATCC
>5.57|378866|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
TCGTCGGTGACCTTAGCTTTCGCCTTTTCCACC
>5.58|378927|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
AGTGACCCACAGCCTGCCGAGCAGGGGGAGCTG
>5.59|378988|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
CTGCAGTCAACTCCTCTGCGAACGCCGCTGCCC
>5.60|379049|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
AAACTCAGCAAATCTCATCAACGATGACGACAG
>5.61|379110|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
CGAGTAATGATCGCGTTGATTAGGACTGGATAG
>5.62|379171|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
TTGAGTTGCTTGTCCTTGATGAGTGCTTTGATC
>5.63|379232|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GTTTGGTGCGCGTGCACCTTTTCCACCCATCTG
>5.64|379293|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GTGGTCCAGGGTGACGGTTACGTCCACGGTGAC
>5.65|379354|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GCAGCATGTGCGGGGACACAATCAAATCACTCA
>5.66|379415|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
CAATCACCTACCTTGAGCCCAGTCGCAAACGCA
>5.67|379476|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
TATGCGGTGGCGCACCAGGCACGCACAGGGGCT
>5.68|379537|34|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GCCAGATCAAATACCGAATCAGGGACGATAAGCT
>5.69|379599|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
CTGTTACTGAGACAATCGCTGATCCTGCGCGTC
>5.70|379660|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
CTGAGATCAATTCGTTGGTTGCGGATCAAAAGC
>5.71|379721|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GCACGGCCTAGTCCCCTATACGATGACGGCCAG
>5.72|379782|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GACGCGAAACTTCCGCCGTTTTTTGCCCATTCG
>5.73|379843|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GTTCATGGTTTTGCGATTGATTCCATGATCACC
>5.74|379904|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
TGAGGGTGCTGGGAATTTGGGTGCTATCAACGC
>5.75|379965|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
TGGAGCGTGACAGCACCATCACCCACACCGTCA
>5.76|380026|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
GATTCCGCAGAGACCCGCACTAGTGGTGAAATC
>5.77|380087|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
AAATCGCGCACCTTCGCACCGGCCATTTTCAGC
>5.78|380148|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR
ATCACGGTGTGGGGGCATTTTTTCATGCCCCAC

CRISPR arrays and Neighbor proteins around NZ_CP010451_5

CRISPR arrays

The CRISPR arrays of NZ_CP010451_5

>merge|NZ_CP010451|5|375420-380208|CRISPRCasFinder,CRT,PILER-CR
GGACCATCCCCGCCTGAGCGGGGAGAACGCTGATGAGCCGGGCGCTTGGATTGACATCGATGGACCATCCCCGCCTGAGCGGGGAGAACAAGAGGTGCGTAACCGTCAGCGGGATGAGGAACGGACCATCCCCGCCTGAGCGGGGAGAACACCCCAGACCAGCTGCCTGCAGCCCATGGATCAGGACCATCCCCGCCTGAGCGGGGAGAACGCTGTCAATGAGGTCACGACGATCGCGATTACGGGACCATCCCCGCCTGAGCGGGGAGAACTGGTTGTATTTTTGCTGCGCCTCCAAGAAAGCCGGACCATCCCCGCCTGAGCGGGGAGAACCCGCATCCAAAGCTTCCTGAGCCGAATACCACGGGACCATCCCCGCCTGAGCGGGGAGAACGCGGTAACCCATGAGACGCTCAGGGGCATCCGGGGACCATCCCCGCCTGAGCGGGGAGAACGAGAAGGTGGAGACCATCGAAATCGACGTCACCGGACCATCCCCGCCTGAGCGGGGAGAACGAATCAGCATTGGGTTTTCATGTGGTCGCCAACGGACCATCCCCGCCTGAGCGGGGAGAACGTTTTCCTGTGTTAGCGATGGCACCTCTTCGCCGGACCATCCCCGCCTGAGCGGGGAGAACTAAGCCCGCTGATGATCAAGCAAATACTTGTACGGACCATCCCCGCCTGAGCGGGGAGAACAAGGGGCAGGTGCAATCCCTTGCCGGTGACGCGGGACCATCCCCGCCTGAGCGGGGAGAACTGAGGCCATATTTCAGAGATGTTGTCTTAGATGGGACCATCCCCGCCTGAGCGGGGAGAACTGCCGCAGCGCTAGACACAATGGCATGCGCTACGGACCATCCCCGCCTGAGCGGGGAGAACTTGCTCTTGCGGAGGACATCGTCCAGGTTTGAGGGACCATCCCCGCCTGAGCGGGGAGAACGCTTGAGTGGGATATTGTTACCGGCGCTCTCACGGACCATCCCCGCCTGAGCGGGGAGAACTGAAGCCCCGCTGGTGGGCGGGGCTTGAAGTAGGGACCATCCCCGCCTGAGCGGGGAGAACACACTCATCTCCGCATAGGTGTCCAACCCCCACGGACCATCCCCGCCTGAGCGGGGAGAACACTCAGGCCACCACTCGGGCACTGAATCGGCGGGGACCATCCCCGCCTGAGCGGGGAGAACACTCAGTGTCAAAATCACCAAAACTGCTATTACGGACCATCCCCGCCTGAGCGGGGAGAACGGTGCAACGCTTCAAGAACCGCCGATGATTGAGGGACCATCCCCGCCTGAGCGGGGAGAACACGGCACCCACACCCAGTCGTACCACACGGTCGGGACCATCCCCGCCTGAGCGGGGAGAACTGCTGCACATGGCCCACGGTCGTGGTCGCAGCAGGACCATCCCCGCCTGAGCGGGGAGAACCCCTCCACTGAGAGCGTAGATCCAGTGGAGAGCGGACCATCCCCGCCTGAGCGGGGAGAACTTGCTCTTGCGGAGGACATCGTCCAGGTTTGAGGGACCATCCCCGCCTGAGCGGGGAGAACGGCATCCAGGTGTGCTCCACCCGGTACACCGCGGGACCATCCCCGCCTGAGCGGGGAGAACATGTGCCGCCCACTATTAAAGGTGCAACCAACAGGACCATCCCCGCCTGAGCGGGGAGAACAAAGGGAGATCGCTGATTACTTGTCTGAGCAGCGGACCATCCCCGCCTGAGCGGGGAGAACGCGATTGATAAAACAGGTGATGCTGTAGCTGAAGGACCATCCCCGCCTGAGCGGGGAGAACGAGTCGAACCTCCAAGCTATTGCTTGAGTCGGTTGGACCATCCCCGCCTGAGCGGGGAGAACAGCTAGATCCAAGCACAACTGGTTCCGATATTAGGACCATCCCCGCCTGAGCGGGGAGAACTGAGGAGTCCCGCCGTGGCCGGTAAAAGCGCCGGGACCATCCCCGCCTGAGCGGGGAGAACCCGACTTTAAGCGCAACGAAGCCCTCAACGACGGGACCATCCCCGCCTGAGCGGGGAGAACGGGGAACCACTGGATGGTTCCTGCGGTAGGCGGGGACCATCCCCGCCTGAGCGGGGAGAACTGCAGGGCAAGCGCACCGACGGAGTGCATTGGGGGACCATCCCCGCCTGAGCGGGGAGAACTGAATCCTTACCACGAGGCCATGCAGCAATCGGGGACCATCCCCGCCTGAGCGGGGAGAACCGGAGGGTAAGACGAAAGTGTCTAATATTCTTGGGACCATCCCCGCCTGAGCGGGGAGAACTAAGCAAAAAGATTACGAGCTTTCCCGCTTCGCGGACCATCCCCGCCTGAGCGGGGAGAACGTGGTCAAATCCATTAGTGTCTCCTAAATTGGGGGACCATCCCCGCCTGAGCGGGGAGAACAAGGTGTCGGTATTGAACCACACTCCGCTGGCCGGACCATCCCCGCCTGAGCGGGGAGAACATACCCACTAGCGTTTGCAAGTCTTTACCGTCAGGACCATCCCCGCCTGAGCGGGGAGAACGGCATGGCACAAGAGGATCGACAGGAAGCCGCAGGACCATCCCCGCCTGAGCGGGGAGAACGGGGAACCTGTACCAAATCCGTTTCCACCTGCCGGACCATCCCCGCCTGAGCGGGGAGAACGTGTCACCCGCCTCAAGAACGATGGTGCCGGACGGACCATCCCCGCCTGAGCGGGGAGAACCAGACTGGCCGAATCCAGATCGATGACCTTGGGGGACCATCCCCGCCTGAGCGGGGAGAACGTCAGCGGCTTCCTCAACGTCGGTTGCCAAACCGGGACCATCCCCGCCTGAGCGGGGAGAACTTCTGAGCAGCCTGAACCGCCAACGAACCCTTGGGACCATCCCCGCCTGAGCGGGGAGAACATAATGAGTTACATGAACAACCACAAACAATGGGGACCATCCCCGCCTGAGCGGGGAGAACTCGTCTTATGGGCGTTGGCAGGACACTATGGCGGGACCATCCCCGCCTGAGCGGGGAGAACTCTTCGCCTTGGCGTACCCCTCCTTGTATTCGGGGACCATCCCCGCCTGAGCGGGGAGAACTATTCGGGTTCCCGGTGGTGGAACCCAACCATGGGACCATCCCCGCCTGAGCGGGGAGAACTGCAGGCGCGTTCTGGTTCTGCTGCATGCGCTGGGACCATCCCCGCCTGAGCGGGGAGAACGGCTCGGTGAGCTTCACGCGATCCTGTTTGCGGGGACCATCCCCGCCTGAGCGGGGAGAACATTCGCCATCTTTGGCGTGATCCGGGCGGGCGGGGACCATCCCCGCCTGAGCGGGGAGAACGGAATCCGGTCACTTGGATCCACAAGCAATACCGGACCATCCCCGCCTGAGCGGGGAGAACGGGCCAAAACCGCTAGTCAGCGTGTATGAATCCGGACCATCCCCGCCTGAGCGGGGAGAACTCGTCGGTGACCTTAGCTTTCGCCTTTTCCACCGGACCATCCCCGCCTGAGCGGGGAGAACAGTGACCCACAGCCTGCCGAGCAGGGGGAGCTGGGACCATCCCCGCCTGAGCGGGGAGAACCTGCAGTCAACTCCTCTGCGAACGCCGCTGCCCGGACCATCCCCGCCTGAGCGGGGAGAACAAACTCAGCAAATCTCATCAACGATGACGACAGGGACCATCCCCGCCTGAGCGGGGAGAACCGAGTAATGATCGCGTTGATTAGGACTGGATAGGGACCATCCCCGCCTGAGCGGGGAGAACTTGAGTTGCTTGTCCTTGATGAGTGCTTTGATCGGACCATCCCCGCCTGAGCGGGGAGAACGTTTGGTGCGCGTGCACCTTTTCCACCCATCTGGGACCATCCCCGCCTGAGCGGGGAGAACGTGGTCCAGGGTGACGGTTACGTCCACGGTGACGGACCATCCCCGCCTGAGCGGGGAGAACGCAGCATGTGCGGGGACACAATCAAATCACTCAGGACCATCCCCGCCTGAGCGGGGAGAACCAATCACCTACCTTGAGCCCAGTCGCAAACGCAGGACCATCCCCGCCTGAGCGGGGAGAACTATGCGGTGGCGCACCAGGCACGCACAGGGGCTGGACCATCCCCGCCTGAGCGGGGAGAACGCCAGATCAAATACCGAATCAGGGACGATAAGCTGGACCATCCCCGCCTGAGCGGGGAGAACCTGTTACTGAGACAATCGCTGATCCTGCGCGTCGGACCATCCCCGCCTGAGCGGGGAGAACCTGAGATCAATTCGTTGGTTGCGGATCAAAAGCGGACCATCCCCGCCTGAGCGGGGAGAACGCACGGCCTAGTCCCCTATACGATGACGGCCAGGGACCATCCCCGCCTGAGCGGGGAGAACGACGCGAAACTTCCGCCGTTTTTTGCCCATTCGGGACCATCCCCGCCTGAGCGGGGAGAACGTTCATGGTTTTGCGATTGATTCCATGATCACCGGACCATCCCCGCCTGAGCGGGGAGAACTGAGGGTGCTGGGAATTTGGGTGCTATCAACGCGGACCATCCCCGCCTGAGCGGGGAGAACTGGAGCGTGACAGCACCATCACCCACACCGTCAGGACCATCCCCGCCTGAGCGGGGAGAACGATTCCGCAGAGACCCGCACTAGTGGTGAAATCGGACCATCCCCGCCTGAGCGGGGAGAACAAATCGCGCACCTTCGCACCGGCCATTTTCAGCGGACCATCCCCGCCTGAGCGGGGAGAACATCACGGTGTGGGGGCATTTTTTCATGCCCCACGGACCATCCCCGCCTGAGCGGGGAGAAC

>NZ_CP010451|5|5|375420-380208|CRISPRCasFinder
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCTGATGAGCCGGGCGCTTGGATTGACATCGAT
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAGAGGTGCGTAACCGTCAGCGGGATGAGGAAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACCCCAGACCAGCTGCCTGCAGCCCATGGATCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCTGTCAATGAGGTCACGACGATCGCGATTACG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGGTTGTATTTTTGCTGCGCCTCCAAGAAAGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCGCATCCAAAGCTTCCTGAGCCGAATACCACG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCGGTAACCCATGAGACGCTCAGGGGCATCCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAGAAGGTGGAGACCATCGAAATCGACGTCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAATCAGCATTGGGTTTTCATGTGGTCGCCAAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTTTTCCTGTGTTAGCGATGGCACCTCTTCGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TAAGCCCGCTGATGATCAAGCAAATACTTGTAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAGGGGCAGGTGCAATCCCTTGCCGGTGACGCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAGGCCATATTTCAGAGATGTTGTCTTAGATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCCGCAGCGCTAGACACAATGGCATGCGCTAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTGCTCTTGCGGAGGACATCGTCCAGGTTTGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCTTGAGTGGGATATTGTTACCGGCGCTCTCAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAAGCCCCGCTGGTGGGCGGGGCTTGAAGTAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACACTCATCTCCGCATAGGTGTCCAACCCCCAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACTCAGGCCACCACTCGGGCACTGAATCGGCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACTCAGTGTCAAAATCACCAAAACTGCTATTAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGTGCAACGCTTCAAGAACCGCCGATGATTGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACGGCACCCACACCCAGTCGTACCACACGGTCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCTGCACATGGCCCACGGTCGTGGTCGCAGCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCCTCCACTGAGAGCGTAGATCCAGTGGAGAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTGCTCTTGCGGAGGACATCGTCCAGGTTTGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGCATCCAGGTGTGCTCCACCCGGTACACCGCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATGTGCCGCCCACTATTAAAGGTGCAACCAACA
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAAGGGAGATCGCTGATTACTTGTCTGAGCAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCGATTGATAAAACAGGTGATGCTGTAGCTGAA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAGTCGAACCTCCAAGCTATTGCTTGAGTCGGTT
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGCTAGATCCAAGCACAACTGGTTCCGATATTA
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAGGAGTCCCGCCGTGGCCGGTAAAAGCGCCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCGACTTTAAGCGCAACGAAGCCCTCAACGACG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGGAACCACTGGATGGTTCCTGCGGTAGGCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCAGGGCAAGCGCACCGACGGAGTGCATTGGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAATCCTTACCACGAGGCCATGCAGCAATCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGGAGGGTAAGACGAAAGTGTCTAATATTCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TAAGCAAAAAGATTACGAGCTTTCCCGCTTCGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTGGTCAAATCCATTAGTGTCTCCTAAATTGGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAGGTGTCGGTATTGAACCACACTCCGCTGGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATACCCACTAGCGTTTGCAAGTCTTTACCGTCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGCATGGCACAAGAGGATCGACAGGAAGCCGCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGGAACCTGTACCAAATCCGTTTCCACCTGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTGTCACCCGCCTCAAGAACGATGGTGCCGGAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAGACTGGCCGAATCCAGATCGATGACCTTGGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTCAGCGGCTTCCTCAACGTCGGTTGCCAAACCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTCTGAGCAGCCTGAACCGCCAACGAACCCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATAATGAGTTACATGAACAACCACAAACAATGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCGTCTTATGGGCGTTGGCAGGACACTATGGCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCTTCGCCTTGGCGTACCCCTCCTTGTATTCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TATTCGGGTTCCCGGTGGTGGAACCCAACCATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCAGGCGCGTTCTGGTTCTGCTGCATGCGCTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGCTCGGTGAGCTTCACGCGATCCTGTTTGCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATTCGCCATCTTTGGCGTGATCCGGGCGGGCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGAATCCGGTCACTTGGATCCACAAGCAATACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGCCAAAACCGCTAGTCAGCGTGTATGAATCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCGTCGGTGACCTTAGCTTTCGCCTTTTCCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGTGACCCACAGCCTGCCGAGCAGGGGGAGCTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTGCAGTCAACTCCTCTGCGAACGCCGCTGCCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAACTCAGCAAATCTCATCAACGATGACGACAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGAGTAATGATCGCGTTGATTAGGACTGGATAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTGAGTTGCTTGTCCTTGATGAGTGCTTTGATC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTTTGGTGCGCGTGCACCTTTTCCACCCATCTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTGGTCCAGGGTGACGGTTACGTCCACGGTGAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCAGCATGTGCGGGGACACAATCAAATCACTCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAATCACCTACCTTGAGCCCAGTCGCAAACGCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	TATGCGGTGGCGCACCAGGCACGCACAGGGGCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCCAGATCAAATACCGAATCAGGGACGATAAGCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTGTTACTGAGACAATCGCTGATCCTGCGCGTC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTGAGATCAATTCGTTGGTTGCGGATCAAAAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCACGGCCTAGTCCCCTATACGATGACGGCCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GACGCGAAACTTCCGCCGTTTTTTGCCCATTCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTTCATGGTTTTGCGATTGATTCCATGATCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAGGGTGCTGGGAATTTGGGTGCTATCAACGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGGAGCGTGACAGCACCATCACCCACACCGTCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GATTCCGCAGAGACCCGCACTAGTGGTGAAATC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAATCGCGCACCTTCGCACCGGCCATTTTCAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATCACGGTGTGGGGGCATTTTTTCATGCCCCAC
GGACCATCCCCGCCTGAGCGGGGAGAAC

>NZ_CP010451|5|3|375420-380208|CRT
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCTGATGAGCCGGGCGCTTGGATTGACATCGAT
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAGAGGTGCGTAACCGTCAGCGGGATGAGGAAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACCCCAGACCAGCTGCCTGCAGCCCATGGATCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCTGTCAATGAGGTCACGACGATCGCGATTACG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGGTTGTATTTTTGCTGCGCCTCCAAGAAAGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCGCATCCAAAGCTTCCTGAGCCGAATACCACG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCGGTAACCCATGAGACGCTCAGGGGCATCCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAGAAGGTGGAGACCATCGAAATCGACGTCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAATCAGCATTGGGTTTTCATGTGGTCGCCAAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTTTTCCTGTGTTAGCGATGGCACCTCTTCGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TAAGCCCGCTGATGATCAAGCAAATACTTGTAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAGGGGCAGGTGCAATCCCTTGCCGGTGACGCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAGGCCATATTTCAGAGATGTTGTCTTAGATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCCGCAGCGCTAGACACAATGGCATGCGCTAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTGCTCTTGCGGAGGACATCGTCCAGGTTTGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCTTGAGTGGGATATTGTTACCGGCGCTCTCAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAAGCCCCGCTGGTGGGCGGGGCTTGAAGTAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACACTCATCTCCGCATAGGTGTCCAACCCCCAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACTCAGGCCACCACTCGGGCACTGAATCGGCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACTCAGTGTCAAAATCACCAAAACTGCTATTAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGTGCAACGCTTCAAGAACCGCCGATGATTGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ACGGCACCCACACCCAGTCGTACCACACGGTCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCTGCACATGGCCCACGGTCGTGGTCGCAGCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCCTCCACTGAGAGCGTAGATCCAGTGGAGAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTGCTCTTGCGGAGGACATCGTCCAGGTTTGAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGCATCCAGGTGTGCTCCACCCGGTACACCGCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATGTGCCGCCCACTATTAAAGGTGCAACCAACA
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAAGGGAGATCGCTGATTACTTGTCTGAGCAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCGATTGATAAAACAGGTGATGCTGTAGCTGAA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GAGTCGAACCTCCAAGCTATTGCTTGAGTCGGTT
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGCTAGATCCAAGCACAACTGGTTCCGATATTA
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAGGAGTCCCGCCGTGGCCGGTAAAAGCGCCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CCGACTTTAAGCGCAACGAAGCCCTCAACGACG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGGAACCACTGGATGGTTCCTGCGGTAGGCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCAGGGCAAGCGCACCGACGGAGTGCATTGGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAATCCTTACCACGAGGCCATGCAGCAATCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGGAGGGTAAGACGAAAGTGTCTAATATTCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TAAGCAAAAAGATTACGAGCTTTCCCGCTTCGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTGGTCAAATCCATTAGTGTCTCCTAAATTGGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAGGTGTCGGTATTGAACCACACTCCGCTGGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATACCCACTAGCGTTTGCAAGTCTTTACCGTCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGCATGGCACAAGAGGATCGACAGGAAGCCGCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGGAACCTGTACCAAATCCGTTTCCACCTGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTGTCACCCGCCTCAAGAACGATGGTGCCGGAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAGACTGGCCGAATCCAGATCGATGACCTTGGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTCAGCGGCTTCCTCAACGTCGGTTGCCAAACCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTCTGAGCAGCCTGAACCGCCAACGAACCCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATAATGAGTTACATGAACAACCACAAACAATGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCGTCTTATGGGCGTTGGCAGGACACTATGGCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCTTCGCCTTGGCGTACCCCTCCTTGTATTCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TATTCGGGTTCCCGGTGGTGGAACCCAACCATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCAGGCGCGTTCTGGTTCTGCTGCATGCGCTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGCTCGGTGAGCTTCACGCGATCCTGTTTGCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATTCGCCATCTTTGGCGTGATCCGGGCGGGCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGAATCCGGTCACTTGGATCCACAAGCAATACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGCCAAAACCGCTAGTCAGCGTGTATGAATCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCGTCGGTGACCTTAGCTTTCGCCTTTTCCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGTGACCCACAGCCTGCCGAGCAGGGGGAGCTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTGCAGTCAACTCCTCTGCGAACGCCGCTGCCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAACTCAGCAAATCTCATCAACGATGACGACAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGAGTAATGATCGCGTTGATTAGGACTGGATAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTGAGTTGCTTGTCCTTGATGAGTGCTTTGATC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTTTGGTGCGCGTGCACCTTTTCCACCCATCTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTGGTCCAGGGTGACGGTTACGTCCACGGTGAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCAGCATGTGCGGGGACACAATCAAATCACTCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAATCACCTACCTTGAGCCCAGTCGCAAACGCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	TATGCGGTGGCGCACCAGGCACGCACAGGGGCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCCAGATCAAATACCGAATCAGGGACGATAAGCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTGTTACTGAGACAATCGCTGATCCTGCGCGTC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTGAGATCAATTCGTTGGTTGCGGATCAAAAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCACGGCCTAGTCCCCTATACGATGACGGCCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GACGCGAAACTTCCGCCGTTTTTTGCCCATTCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTTCATGGTTTTGCGATTGATTCCATGATCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAGGGTGCTGGGAATTTGGGTGCTATCAACGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGGAGCGTGACAGCACCATCACCCACACCGTCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GATTCCGCAGAGACCCGCACTAGTGGTGAAATC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAATCGCGCACCTTCGCACCGGCCATTTTCAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATCACGGTGTGGGGGCATTTTTTCATGCCCCAC
GGACCATCCCCGCCTGAGCGGGGAGAAC

>NZ_CP010451|5|3|377983-380208|PILER-CR
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGGAACCTGTACCAAATCCGTTTCCACCTGCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTGTCACCCGCCTCAAGAACGATGGTGCCGGAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAGACTGGCCGAATCCAGATCGATGACCTTGGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTCAGCGGCTTCCTCAACGTCGGTTGCCAAACCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTCTGAGCAGCCTGAACCGCCAACGAACCCTTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATAATGAGTTACATGAACAACCACAAACAATGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCGTCTTATGGGCGTTGGCAGGACACTATGGCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCTTCGCCTTGGCGTACCCCTCCTTGTATTCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TATTCGGGTTCCCGGTGGTGGAACCCAACCATG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGCAGGCGCGTTCTGGTTCTGCTGCATGCGCTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGCTCGGTGAGCTTCACGCGATCCTGTTTGCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATTCGCCATCTTTGGCGTGATCCGGGCGGGCGG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGAATCCGGTCACTTGGATCCACAAGCAATACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GGGCCAAAACCGCTAGTCAGCGTGTATGAATCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TCGTCGGTGACCTTAGCTTTCGCCTTTTCCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AGTGACCCACAGCCTGCCGAGCAGGGGGAGCTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTGCAGTCAACTCCTCTGCGAACGCCGCTGCCC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAACTCAGCAAATCTCATCAACGATGACGACAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	CGAGTAATGATCGCGTTGATTAGGACTGGATAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	TTGAGTTGCTTGTCCTTGATGAGTGCTTTGATC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTTTGGTGCGCGTGCACCTTTTCCACCCATCTG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTGGTCCAGGGTGACGGTTACGTCCACGGTGAC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCAGCATGTGCGGGGACACAATCAAATCACTCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	CAATCACCTACCTTGAGCCCAGTCGCAAACGCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	TATGCGGTGGCGCACCAGGCACGCACAGGGGCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCCAGATCAAATACCGAATCAGGGACGATAAGCT
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTGTTACTGAGACAATCGCTGATCCTGCGCGTC
GGACCATCCCCGCCTGAGCGGGGAGAAC	CTGAGATCAATTCGTTGGTTGCGGATCAAAAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	GCACGGCCTAGTCCCCTATACGATGACGGCCAG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GACGCGAAACTTCCGCCGTTTTTTGCCCATTCG
GGACCATCCCCGCCTGAGCGGGGAGAAC	GTTCATGGTTTTGCGATTGATTCCATGATCACC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGAGGGTGCTGGGAATTTGGGTGCTATCAACGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	TGGAGCGTGACAGCACCATCACCCACACCGTCA
GGACCATCCCCGCCTGAGCGGGGAGAAC	GATTCCGCAGAGACCCGCACTAGTGGTGAAATC
GGACCATCCCCGCCTGAGCGGGGAGAAC	AAATCGCGCACCTTCGCACCGGCCATTTTCAGC
GGACCATCCCCGCCTGAGCGGGGAGAAC	ATCACGGTGTGGGGGCATTTTTTCATGCCCCAC
GGACCATCCCCGCCTGAGCGGGGAGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010451.1|WP_040966861.1|358197_359430_+|MFS-transporter	unknown	unknown	gnl|CDD|340883
NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|182031
NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|187850
NZ_CP010451.1|WP_003863266.1|356774_357410_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293792
NZ_CP010451.1|WP_040966864.1|363064_364102_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|224137
NZ_CP010451.1|WP_040966862.1|360839_361217_-|DUF2304-domain-containing-protein	unknown	unknown	gnl|CDD|378376
NZ_CP010451.1|WP_040966873.1|390754_391816_-|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176186
NZ_CP010451.1|WP_040966863.1|362003_363026_+|hypothetical-protein	unknown	unknown	gnl|CDD|223405
NZ_CP010451.1|WP_003855424.1|361213_361924_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133022
NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl|CDD|378189
NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|187776
NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
NZ_CP010451.1|WP_040966866.1|375042_375303_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_040966872.1|389649_390681_+|Abi-family-protein	unknown	unknown	gnl|CDD|377910
NZ_CP010451.1|WP_003855855.1|357439_358111_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP010451.1|WP_038582304.1|359451_360387_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187566
NZ_CP010451.1|WP_040966865.1|364283_366332_+|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl|CDD|223808
NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl|CDD|378191

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	2.4e-100	331.5	5.9
NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	2.1e-63	209.5	0.0
NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	3.1e-61	201.9	0.7
NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.3e-27	90.6	0.0
NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	9.4e-42	137.6	0.0
NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	1.7e-112	371.3	4.6
NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	2.6e-106	349.3	0.0
NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	6.9e-45	147.7	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010451.1|WP_040966861.1|358197_359430_+|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.03572e-15
NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.03684e-79
NZ_CP010451.1|WP_040966873.1|390754_391816_-|NAD(P)-dependent-alcohol-dehydrogenase	gnl|CDD|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	5.09484e-180
NZ_CP010451.1|WP_003863266.1|356774_357410_+|MBL-fold-metallo-hydrolase	gnl|CDD|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	5.51317e-46
NZ_CP010451.1|WP_040966864.1|363064_364102_+|glycosyltransferase-family-2-protein	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	3.57274e-53
NZ_CP010451.1|WP_040966862.1|360839_361217_-|DUF2304-domain-containing-protein	gnl|CDD|378376	pfam10066, DUF2304, Uncharacterized conserved protein (DUF2304). Members of this family of hypothetical archaeal proteins have no known function.	4.97196e-28
NZ_CP010451.1|WP_040966863.1|362003_363026_+|hypothetical-protein	gnl|CDD|223405	COG0328, RnhA, Ribonuclease HI [DNA replication, recombination, and repair].	1.40198e-26
NZ_CP010451.1|WP_003855424.1|361213_361924_-|glycosyltransferase-family-2-protein	gnl|CDD|133022	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.	6.2111e-44
NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.87102e-155
NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	4.89e-74
NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.92035e-115
NZ_CP010451.1|WP_040966865.1|364283_366332_+|bifunctional-metallophosphatase/5'-nucleotidase	gnl|CDD|223808	COG0737, UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism].	9.66953e-82
NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.53645e-33
NZ_CP010451.1|WP_038582304.1|359451_360387_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187566	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs. This subgroup contains UDP-N-acetylglucosamine 4-epimerase of Pseudomonas aeruginosa, WbpP, an extended SDR, that catalyzes the NAD+ dependent conversion of UDP-GlcNAc and UDPGalNA to UDP-Glc and UDP-Gal. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.34964e-117
NZ_CP010451.1|WP_040966872.1|389649_390681_+|Abi-family-protein	gnl|CDD|377910	pfam07751, Abi_2, Abi-like protein. This family, found in various bacterial species, contains sequences that are similar to the Abi group of proteins, which are involved in bacteriophage resistance mediated by abortive infection in Lactococcus species. The proteins are thought to have helix-turn-helix motifs, found in many DNA-binding proteins, allowing them to perform their function.	4.91788e-46
NZ_CP010451.1|WP_003855855.1|357439_358111_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.96274e-26
NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	7.26225e-42
NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187850	cd09719, Cas1_I-E, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.7599e-129
NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	5.53669e-40

Protein sequences

>NZ_CP010451.1|WP_040966866.1|375042_375303_+|hypothetical-protein
MTISIPTTTEDRLCFPRDEQVLLTEAMDLLTCIESSLRVADVDTQMAVARLAELYLGADDGDHFPTVLNKITQLRDRIYIQVDQAN
>NZ_CP010451.1|WP_040966865.1|364283_366332_+|bifunctional-metallophosphatase/5'-nucleotidase
MKRLSRAALAVVATTAVSFSALAVPAFADEASNVELNILGVTDFHGHIAQDLSKGEMGAAGLACYVESERAANPNTSFITVGDNIGGSPFVSSILKDAPTLTALSTIGVDASALGNHEFDAGYEDLAGRVSLDGTGLAQFPYLGANVEGGTPTPAASEVVELGGVRVAYVGSVTDETSTLVSPAGIPGITFTNDLSAVNAEADRIMAAGEADVVIALMHSPARATDAFSTNVDVVFAGHTHEERVETGPARDGKQPLVVIQGMEYGKFVSDVEISYDSTAKKITAIEAVNVDAATASGACGVPNALVTSVAGIVDAAKIASDVEGAKVVATIENSFFRGADSAGETGSNRGVESSLNNLIAEAGLQAINAQTPLNADIGVMNAGGVRADLEAGEVTFSEAFATQNFSNTYGVVDITGADFIEALEQQWKDPAADRPRLALGLSNNVQYSYNPNAAQGERITHVTINGKPIDETKTYRIAGSTFLLSGGDGFTAFTNGTDITDSGLVDIDLFNSYLAANTSVDVRANQASVGIELSGTALADDSSLIPGKELTVDLSALSYTGGEVTPTTVTVTLGAETVTVPVDNTIIPKLDTTGTATATLIVPAGVTELKIETDAGTTFTLPVVATSKPADGSSVGSSAGSLVAILGVLGALGGLLGVFLHSPQGAPFLTQLHALIDQSKP
>NZ_CP010451.1|WP_040966864.1|363064_364102_+|glycosyltransferase-family-2-protein
MSNKRIGVVIVSYGHEQDVANLVDTFADQLKTGDRVVVVDNRKPWVLKDTVGERLEKHGVEIINHDNGGFAAGCNVGAAHIVDDVDLLFFLNPDTVIDDPTLFNSLRRVDEQWAAFMPYLLLPDGTINSAGNALHISGLSWVTGLDEKPVEGSSEVTDISIASGACLAVRVEWWKRLGGMEELYFMYHEDTDFSARLLLAGGRIGLLHSAYVTHHYDYAKGDYKWIYIERNRHVLLLSVLPLPLLLMLIPQILGVNLGLWAIAAKENRVGLKVKSLRLLIRDLPAIFKLRRSTQELAELTPSQYLAKMEWRLDNPNLGNIGSNKIVATVYKTYYKLCMSILKLLA
>NZ_CP010451.1|WP_040966863.1|362003_363026_+|hypothetical-protein
MKSIDLEQLAGTQSRTYQSRKITDEMVARPVHVAIALWEVPWESAKSGKIEGWVIAVDSPRGRFVRSGQTKNGDAVNRTVSMLKSALKGVRGKAWIVTGRRQAALRAALVRENYLVTGSFAEQNRAGVKASAISRRAEQSALYKAKKIGEFAERAPRVKERQEAHWWPRLSRTQGTAGVLRLATDASTDGVFRGAMCFVASNGDYLLETQDTTASSDELELESITHALIYLKTIGATQAIIESDSKAALEAIDFILNTRPRRGRWRGITARARNRFRDAWEALIDDCVVELSRVLGHAGDPLNQAADQIAYMGMRAVIFEQKSAHPTLLKGIDKALRKAE
>NZ_CP010451.1|WP_003855424.1|361213_361924_-|glycosyltransferase-family-2-protein
MDASKNSDFKDTWLVVPCYNEATVIREVLENALKTFPNIVAVNDGSPDNSAEEIHAAGAHLVNHPVNLGQGAAIQTGIEYARKQPGAKYFVTFDADGQHQVKDVVRMVERLRAEDVDIIVGTRFGRPRQADDQVPLIKRLVLRTVVLLSPKTRRLGLTDAHNGLRVFNQKVAQEMNIRMNGMSHASEIVDQIDERGWRISEEPVDILYTEYSMSKGQSLLNGVNILADGFLARRLP
>NZ_CP010451.1|WP_040966862.1|360839_361217_-|DUF2304-domain-containing-protein
MTQTTTQIIIQILLLLATAALALYFLRNRRKARAKAWVKIGFVVFIFAAVWAVIRPDDLTQLANFVGVDRGTDLMLYALVVAFMFTTLSSYVRFREQELRYSKLARAVALQNAVLPEDSQGSDPA
>NZ_CP010451.1|WP_038582304.1|359451_360387_+|NAD-dependent-epimerase/dehydratase-family-protein
MRTVVTGGAGFIGSHLVDLLIKEGHEVVVIDNLSRGRLENLSDAEATGKLTFVEADLLDVDFNEFLGTHKPEVIFHLAAQIDVRHSVVDPLHDAETNILSTIRIADAARQHGVRKVVFTSSGGSIYGEPSEFPVDETVPVDPHSPYAASKVSGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFALRLLGGLDTKVFGDGGNTRDYVYVGDVVRAFYLASGEIGGGERFNIGTSVETSDRQLHTLVAAAAGSKDDPEYAPARLGDVPRSALSFGKAKEVLGWEPEVNIEQGVAKTVEYFRTH
>NZ_CP010451.1|WP_040966861.1|358197_359430_+|MFS-transporter
MGVSAFNMSDMVANKRAQRKVWLAVALSVFTVAWGGNEFTPLLVFYRGEGFFSNLFIDLLLVFYAIGVAVGLLAAGPLSDRYGRRAVMLPAPLIAILGSALIASGEETAILIAIGRVLSGISVGMVMTAGGSWIKELSSSRFEPGVKTSAGAKRASMSLTGGFALGPALAGVMAQWLPLPGQLAYVLHIILTLILFPLLITAPETRQSAHLKTKGSFWSDVLVPSALDKRFLFVVAPIGPWVFGAGFTAYAVLPSQLRDMVSAPVAYSALIALVTLGSGFGIQQFGPQIMGTSKTRGPILAMFVTVIGMIGAVIVVMNPHPWWALVVCMALGLSYGLCMFMGLAETQNIAPPIDMAGLTGIFYCLTYVGMVFPALMTWLNQWLSYPFMLGFGAVMATICLIIVSFSARRF
>NZ_CP010451.1|WP_003855855.1|357439_358111_+|SDR-family-oxidoreductase
MDLKLGGQVILVVGGAGTIGSEVVKLLTEEGATAVAASRSTPLSIDASDEASVRAGIDQVIAEHGRLDGLVVSSAPAAQTLSAETADDPDTVLAAIEGKAITFMKAATVALEKMREAGYGRIVALSGMNSYKTLSTAASARNAALNVVVKNLADRHAGTGITVNAISPGFVVAEPDAEVNRANGDTTVGEVAEAIAFLLSPRTASISGEIISVGHKAKGVILP
>NZ_CP010451.1|WP_003863266.1|356774_357410_+|MBL-fold-metallo-hydrolase
MAHDGLRVENIVTSGIFALDGGEWEVDNNIWVVGNDDEVFIIDAAHTAAPIIEAVGGRTVKGILCTHAHNDHITVAPELAKEFDAPIFVHPGDQMLWEETHGNLAHEDLADQQKFQIAGTELIVLNTPGHSPGSSCFYLPEANELFSGDTLFQGGPGATGRKYSSFDTIIESLKTSILDLPAETTVRTGHGDHTSVGAEAPHLEEWIKRGH
>NZ_CP010451.1|WP_074508531.1|380251_380605_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MITVILSSPPEKLRGHLTRWLIEVSPGVFVGRPTARVRDEIWDMIVSTLTNGRAVMTFPTRDNEQGFDIRVHRSQWEKTDFEGVTLMRHPISTAKGSMKAGWSTASQHRAARRRKAK
>NZ_CP010451.1|WP_040966867.1|380601_381582_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MQSGMPPSTPMQLSRATDRISFLYLEHCTLGRDGGALTATDDKGVVHVPVAALSVLLLGPGTRLTHQAVSVVADSGCSIVWVGEEGVRYYAHGRSIARSDRLLVKQAEKVSNTRSRLAVARAMYDMRFPNEDTSSLTMQQLRGKEGARVRKIYRQNSEEYGVDWNRRMYDPDDFLSGDPINQALSAAHTCLYGLCHSVIVSLGCSPGLGFVHTGHDRSFVYDIADLYKAELSIPVAFQVVSDLNKNGRAEMSDVSSITRRAMRDAFKQLRLAERVAADLKTLLIDEETVSSEEFWADIVQLWDGNDRRVSGGTNYGDPVHFPESEK
>NZ_CP010451.1|WP_040966868.1|381587_382238_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYMSRMYLNPQRRQTRELLANPQKLHAAVLSSFPPSSSETTDEGRVLWRVDQTRESVALYVVSPAIPSFEHLQEQAGWSQEQSWQSSDYTAMLNRIVKGQKYAFRLTANPVHTVTEDGVKRRKAHLTPAHQLDWLTDREEQLGASFTGEAGEITAITTKSERRVFRREKRTVTIQQVTFEGSLEVKDANKLREVLCNGIGKARGYGCGLLTLAPME
>NZ_CP010451.1|WP_040966869.1|382238_382937_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MPTLLLRLSGPMQSWGVSGRFVNRSTSSSPTKSGVIGLLAAAEGRPREQSVADLVNLRFGVRTDQVGSVLRDFQTEIDWRTNKAKPLTNRYYLQDYRFLAAIEGPQEILEGLETALKNPVFPLYLGRRSCPPGERVPLKIVNENLEIALQKSDWLAADWYRKKASTSVRLPISRDLLPGESADELIRDLPESFDPKERRYELRPIKHDSVTISNEVGKKPIDHDPFSLIGGV
>NZ_CP010451.1|WP_040966870.1|382936_384058_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSTFVDIHLVQLVPPSCINRDDTGSPKSAIFGGVERHRVSSQAWKRAVRNDFKDYLDSSELGERTLQAVKRVSQRIQELKEELSAEQAEAAAEEILKTAGIALEKKKKDETLPTKTGYLLFLSRAEIDALAELAIAQVEGNKPTKKQAREALQGPQAIDVALFGRMLADAPEANVDASCQVEHALSVHKATREFDYYTAVDDNADEDNAGAGMIGTQEFVSSALYRYATVNVDKLVENVGDADAAARAIEAFVRSFTVSMPTGKQNTFANRTRPDFVYVEVRNDQPVSLVNAFENPVRNEGKAVSLAAAKLAEYAVNGDAAYGTKPVDSFGMANTNVDSEELEKTFGDRWDATSFEDIIKRAGAAARTSTQEN
>NZ_CP010451.1|WP_052461388.1|384076_384697_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSEKTSVSNRSAVVSHVAKKLHELEAHLSAGTSRSKADLAKLRRAVGKAPGAIPDVWGITLEDLPEQLVGKTDAPSWGETSVHNALALFALHQQGKGDSMNQRGEGLGRAVRQYILTKDPGGGFDNESPILRRFNALSTSDSVDELLWHLRNTITQLRASNVKLDFAELAGQLYDFHIPEARDRVRLAWGRQLYTAPKTTEKASES
>NZ_CP010451.1|WP_040966871.1|384689_386357_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSDNTVFNLLDEPWIEVLRIDGSPDTVSIKELLENAEHYQRLAASLETVNFAILRVLLAILYRSWDSPQWRNQMAASKHWQQKWVSRSVFDSEVEDYLDELEDRFDLRHPERPFMQVADLHTSKNEWKSLDILIPDAGEVGDLFTMRTDIASLSPASAAAFLIHTNAFDYSGIKSGAVGDDRVKGGRGYPIGIGWAGWLGGTTLEGHNLLETLLLNYVPQREQAGSDEDVPVWELEDPLTSSARPGFEDNALIAKAAGPVELLTWPQRRLRLKWENDQVTGVLISNGDALGYTVQDQVETMSPWRFSDPQTTKAKRLRYMPASVQPGRAMWRTLPNLLPNQNFAKAQTKYSDNAPQSKPAKTVEWVGQLSAQGYLDPTFPIRMRMVSMEYGAQSSSYADILSDSVHLSALLLSPDGEVLRSIARLAIERTEQVDYAVRQYNSNIAFAVSGDTASDTDEVQREFFFSIDGPFREWLTKLSESKDPDALLVEWDAQLRQTARAQAEQILSKQPPSVWSGRMKDSNRITGPVALNRLQGSLNKILGENLNSKKGVEDE
>NZ_CP010451.1|WP_080770707.1|386377_389152_-|CRISPR-associated-helicase/endonuclease-Cas3
MQIVIDLEVFWAKFVEKTSEHMSLLQHSRDITSVINEVSKKLLAPASEEFLQSILGETPLHEILTLAAISHDVGKASPYFQQKVPSLSQRVTHQGYGSDVTSKEIYANPHSIISAHTLIAWFEQHRGFKLSPPDREFWFHVIAGHHGSYSEFSLPSDALLREIRIWPEWQEARFALLDKLTSEHDLDEESLHGLASIFGDRMENNMLSTSAAALITGLLISADWVASSSDNFPLTNGEPQDQDYRTEDALTRINLGNHWQPGEVTTESFLDRFSLPASATMRNVQEAVVELGHQLDKPALVILENETGSGKTEAALALAEIMAEKFGFTGLFFAQPTRVTSDAIFTRVAEWLIHSVPEDTISTVLAHGKAEFNDDFKAITTGDLTAIYDDDSSNGDSPLEATQWFRGRKTGLLASVAVGTIDQVLFAVLQSKHNVLRHLGLASKVVIIDEIHAADAYMRVYTTRLLEWLGLYGVPVIALSATLPPKTRKQLIDAYQQGASRYSGRKARIDKAPVYPRITWVDGEKSGTITPEHDGLTRTTHYSFLEGDLEEMADEALKLSVDGGCIGIICSTVSRAQELYKLVSSREEEVVLLHSRFLTSDRAILESALVKKLGRKAGASRPKKLIVVSTQIIEQGLDLDFDAMITDIAPTDLIIQRIGRVHRHQMLNDSRPDSLKVPQLKIFGTGLPDIEASAPEIQTGSKRVYRHAPLLRSIRVLADHATNTDGTITTPDDVESLVTSSYDTKKTAPEAWKDAWTAAHVEERKFETDQESRAETARIPDPLAGKLAEWTKSPSLADEQAAVAQVRDADESFEVVVVQNRMGRLFALPHIKDLEGQSVDGVMELEYRTARTLATCTVRLPEWSLTDDDLFDLEADGQESWQKSRWLKGSLPLVLDENLERALEQYILRYDEQLGLLLERKEQQ
>NZ_CP010451.1|WP_040966872.1|389649_390681_+|Abi-family-protein
MMREPAELKPFKEHDELLQMLEENGLKIPSSEIAKKELRRHGYHRLSGYRYLFREMLPFEQQNSETRTFRSKQHLAGSSFEDVIALAEFDSRLRLSIVEALADFEVRLRTAVAHTLAAKDELAHLKVDKLDRRSCLNTAKGKRETNHEVFCKEVARVTAMAIRSDDFAKHHDETYGSDLPVWAVVEHLTFGSLHYLFGFMKNEDKRTVANAFGLRHPKALEKWLYALVDLRNLSNHSARLFNRSLKRSIVIPPHTVSPGGLLKQTEEFLDRNKQEKDRLYAVVAVLAYLLKSHEFGSEWPTKFREVMLTFPYIELAEFEDPLVSPQKNMGFPEHWQGDELWLP
>NZ_CP010451.1|WP_040966873.1|390754_391816_-|NAD(P)-dependent-alcohol-dehydrogenase
MSIQVKALQKTGPEAPFEVKIIERREPRADDVVIDIKAAGICHSDIHTIRNEWGEAHFPLTVGHEIAGVVSAVGSDVTKWKVGDRVGVGCLVNSCGECEQCVAGFENNCLRGNVGTYNSDDVDGTITQGGYAEKVVVNERFLCSIPEELDFDVAAPLLCAGITTYSPIARWNVKEGDKVAVMGLGGLGHMGVQIAAAKGADVTVLSRSLRKAELAKELGAARTLATSDEDFFTEHAGEFDFILNTISASIPVDKYLSLLKPHGVMAVVGLPPEKQPLSFGALIGGGKVLTGSNIGGIPETQEMLDFCAKHGLGAMIETVGVNDVDAAYDRVVAGDVQFRVVIDTASFAEVEAV

Crispr_ID: NZ_CP010451_6

• CRISPR_ID: NZ_CP010451_6
• CRISPR_location: 846335-846435
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010451_6

Consensus_repeat	Method
AAACTAAAAAGCTCGAGGCTTTTGGTCACCT	CRISPRCasFinder

spacers of NZ_CP010451_6

>6.1|846366|39|NZ_CP010451|CRISPRCasFinder
GGTGTGGTTTCGAGTGTTGAAAACCGTCCTATATGACCG

CRISPR arrays and Neighbor proteins around NZ_CP010451_6

CRISPR arrays

The CRISPR arrays of NZ_CP010451_6

>merge|NZ_CP010451|6|846335-846435|CRISPRCasFinder
AAACTAAAAAGCTCGAGGCTTTTGGTCACCTGGTGTGGTTTCGAGTGTTGAAAACCGTCCTATATGACCGAAACTAAAAAGCTCGAGGCTTTTGGTCACCT

>NZ_CP010451|6|6|846335-846435|CRISPRCasFinder
AAACTAAAAAGCTCGAGGCTTTTGGTCACCT	GGTGTGGTTTCGAGTGTTGAAAACCGTCCTATATGACCG
AAACTAAAAAGCTCGAGGCTTTTGGTCACCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010451.1|WP_003863574.1|842543_843920_+|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl|CDD|236557
NZ_CP010451.1|WP_040967094.1|843994_845002_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_040967099.1|854145_854736_+|ComF-family-protein	unknown	unknown	gnl|CDD|223970
NZ_CP010451.1|WP_040967097.1|848091_849528_+|adenosylhomocysteinase	unknown	unknown	gnl|CDD|377487
NZ_CP010451.1|WP_003858196.1|847627_847981_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_040967093.1|839444_840533_+|NDP-sugar-synthase	unknown	unknown	gnl|CDD|224129
NZ_CP010451.1|WP_040967095.1|845002_846187_+|mannose-6-phosphate-isomerase,-class-I	unknown	unknown	gnl|CDD|380414
NZ_CP010451.1|WP_040967090.1|833480_836369_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|350769
NZ_CP010451.1|WP_003858194.1|849527_850139_+|dTMP-kinase	unknown	unknown	gnl|CDD|236133
NZ_CP010451.1|WP_011013864.1|841518_841923_-|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240574
NZ_CP010451.1|WP_040967091.1|836491_838051_-|LCP-family-protein	unknown	unknown	gnl|CDD|224235
NZ_CP010451.1|WP_003858209.1|840922_841237_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP010451.1|WP_003863575.1|842071_842464_+|DUF3499-domain-containing-protein	unknown	unknown	gnl|CDD|378788
NZ_CP010451.1|WP_040967096.1|846598_847384_-|hypothetical-protein	unknown	unknown	gnl|CDD|223021
NZ_CP010451.1|WP_038583063.1|850163_850844_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP010451.1|WP_040967100.1|855683_858221_+|preprotein-translocase-subunit-SecA	unknown	unknown	gnl|CDD|237259
NZ_CP010451.1|WP_040967098.1|852439_854146_+|MtrAB-system-accessory-protein-LpqB	unknown	unknown	gnl|CDD|237449
NZ_CP010451.1|WP_003858182.1|854879_855545_+|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl|CDD|224461
NZ_CP010451.1|WP_040967092.1|838399_839272_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|224137
NZ_CP010451.1|WP_003863563.1|850943_852443_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010451.1|WP_003858194.1|849527_850139_+|dTMP-kinase	gnl|CDD|236133	PRK07933, PRK07933, dTMP kinase.	6.50318e-102
NZ_CP010451.1|WP_003863574.1|842543_843920_+|phosphomannomutase/phosphoglucomutase	gnl|CDD|236557	PRK09542, manB, phosphomannomutase/phosphoglucomutase; Reviewed.	0
NZ_CP010451.1|WP_040967099.1|854145_854736_+|ComF-family-protein	gnl|CDD|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	5.23873e-29
NZ_CP010451.1|WP_040967097.1|848091_849528_+|adenosylhomocysteinase	gnl|CDD|377487	pfam05221, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.	0
NZ_CP010451.1|WP_040967093.1|839444_840533_+|NDP-sugar-synthase	gnl|CDD|224129	COG1208, GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis].	8.15461e-114
NZ_CP010451.1|WP_040967095.1|845002_846187_+|mannose-6-phosphate-isomerase,-class-I	gnl|CDD|380414	cd07011, cupin_PMI_type_I_N, type I phosphomannose isomerase in eukaryotes and bacteria, N-terminal cupin domain. This subfamily contains type I phosphomannose isomerase (PMI; E.C. 5.3.1.8; also known as mannose-6-phosphate isomerase) found in eukaryotes and some bacteria such as Salmonella enterica. PMI catalyzes the reversible isomerization of fructose-6-phosphate (F6P) and mannose-6-phosphate (M6P), the first committed step in the synthesis of mannosylated glycoproteins. The active site, located within the N-terminal jelly roll-like beta-barrel cupin fold, contains a single essential zinc atom and forms a deep, open cavity large enough to contain M6P or F6P. PMI type I also has a C-terminal beta-barrel fold which has diverged considerably from the N-terminal domain and is not included here. This subfamily contains an alpha helical domain that is found in eukaryotic and some prokaryotic PMIs but is not present in their archaeal counterparts. F6P is a substrate for glycolysis and gluconeogenesis, while M6P is a substrate for production of activated mannose donor guanosine 5'-diphosphate D-mannose, an important precursor of mannosylated biomolecules such as glycoproteins, bacterial exopolysaccharides and fungal cell wall components. PMI is also essential for survival, virulence and possibly pathogenicity of some bacteria and protozoan parasites, as well as for cell wall integrity of certain yeasts. Thus, PMI is a potential target against fungal infections causing serious illness or death.	4.6248e-98
NZ_CP010451.1|WP_040967090.1|833480_836369_-|DEAD/DEAH-box-helicase	gnl|CDD|350769	cd18011, DEXDc_RapA, DEXH-box helicase domain of RapA. In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.14614e-58
NZ_CP010451.1|WP_040967100.1|855683_858221_+|preprotein-translocase-subunit-SecA	gnl|CDD|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP010451.1|WP_011013864.1|841518_841923_-|metallopeptidase-family-protein	gnl|CDD|240574	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria. The subfamily includes some uncharacterized bacterial proteins which show high sequence similarity with Thermus thermophilus hypothetical protein TTHA0227. However, they do not contain the conserved HExxH (x could be any amino acid) motif. They may not have any zinc metallo-peptidase activity.	6.61282e-24
NZ_CP010451.1|WP_040967091.1|836491_838051_-|LCP-family-protein	gnl|CDD|224235	COG1316, LytR, Transcriptional regulator [Transcription].	8.51034e-69
NZ_CP010451.1|WP_003858209.1|840922_841237_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	9.78845e-31
NZ_CP010451.1|WP_003863575.1|842071_842464_+|DUF3499-domain-containing-protein	gnl|CDD|378788	pfam12005, DUF3499, Protein of unknown function (DUF3499). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 125 to 163 amino acids in length.	3.83221e-60
NZ_CP010451.1|WP_040967096.1|846598_847384_-|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	7.6307e-06
NZ_CP010451.1|WP_038583063.1|850163_850844_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.33976e-90
NZ_CP010451.1|WP_040967098.1|852439_854146_+|MtrAB-system-accessory-protein-LpqB	gnl|CDD|237449	PRK13616, PRK13616, MtrAB system accessory protein LpqB.	0
NZ_CP010451.1|WP_003858182.1|854879_855545_+|ribosome-associated-translation-inhibitor-RaiA	gnl|CDD|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.09912e-29
NZ_CP010451.1|WP_040967092.1|838399_839272_+|glycosyltransferase-family-2-protein	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	8.16774e-68
NZ_CP010451.1|WP_003863563.1|850943_852443_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.33589e-53

Protein sequences

>NZ_CP010451.1|WP_040967095.1|845002_846187_+|mannose-6-phosphate-isomerase,-class-I
MELLEGSLRTYPWGSRTLIADLKGEESPSSRPEAEVWFGAHPGSPSTIGGNALNEVIAANPEEALGTRVAEAFENELPFLLKILAAGAPLSLQAHPSLEQAREGFARENSAGIDLAAPNRNYRDPNHKPELIVALTEFIAMAGFRPLRNTLTIFDALACEPLDRYRSMLTVDNEEESLRALFTTWITIPIGKRHELIDALISNAHTYLEASDRDEDIAFVLSHIIELNEQYPGDVGVLGALLLNFYKLAPGEALYLDAANLHAYISGLGVEIMANSDNVLRGGLTSKYVDVPELVRVLDFKSLENARVDVEEDGATTHYPVPINEFRLDRVAVQGEAEANHDGPMIVLCTSGTVSLEAGEKTLEVAAGHAAWVPANDPTIAMRSEDAEVFLARV
>NZ_CP010451.1|WP_040967094.1|843994_845002_+|hypothetical-protein
MVQVDNTFYDGSAYDPETVRFFDVAQEGAQVRLIGGLVAQGALSAFEGLRPRSVVVMIDGQIHRSCVRLVETLHSPMRQPLVITSTLPHYIGALDVLIVITDNGADEKALKALITASQRGVATLLIGPSSGPLIDESPQDTFVLPTLPTAAGLSPARIVASISTLLDLLEADPSIISDRLEHLADCIDEEVESLSPERDELVNPGRKLRAYVDHARIVHTGRTDVGLAIANVIAPIWTRRGLVSAVLDFPELMESLPELRGPEPITDDIFHDPFIDDEPGVVPFRAVVWAEEEPGIPDAMAQSCDGPSKGALTQALRLLVRGQSATTYAIEEKDL
>NZ_CP010451.1|WP_003863574.1|842543_843920_+|phosphomannomutase/phosphoglucomutase
MRTRESVTAVIKAYDVRGVVGVDIDADFISETGAAFGRLMRSEGETTVAIGHDMRDSSPELAKAFADGVTAQGLDVVHLGLTSTDELYFASGTLKCAGAMFTASHNPAEYNGIKLCRAGARPVGQDSGLANIIDDLVEGVPAFDGESGSVSEQDLLSAYAEYLNELVDLKNIRPLKVAVDAANGMGGFTVPEVFKGLPLDVAPLYFELDGNFPNHEANPLEPANLVDLQKFTVETGSDIGLAFDGDADRCFVVDEKGQPVSPSAICAIVAERYLEKLPGSTIIHNLITSKAVPEVIAENGGTAVRTRVGHSFIKAKMAETGAAFGGEHSAHYYFTEFFNADSGILAAMHVLAALGSQDQPLSEMMARYNRYVASGELNSRLANAEAQQERTQAVLDAFADRTESVDTLDGVTVELKDTSAWFNVRASNTEPLLRLNVEAASKEEVDALVAEILGIIRA
>NZ_CP010451.1|WP_003863575.1|842071_842464_+|DUF3499-domain-containing-protein
MSQFRRCSRPGCGKPAVATLTYAYSDSTAVVGPLAPAAEPHSWDLCEHHAERITAPLGWEMLRVNDIKVDDDEDLTALAQAVREAGRTVSGLVPEDEVGGNHPVNRSARIAEQKVHRRGHLYVVPDQDES
>NZ_CP010451.1|WP_011013864.1|841518_841923_-|metallopeptidase-family-protein
MPVEVPRHASRRQAFDRAVLEAYSPLYGIYQKELSNLDIAVDTVPRMRLSADLAILPDEITADGPVPLGRVIPPAIDTKGNPTRARIVIFRMPIEQRVTNAVERHELLTHVLTSLVANYLNIDPRDIDPGFQDL
>NZ_CP010451.1|WP_003858209.1|840922_841237_+|WhiB-family-transcriptional-regulator
MEDSAGDVSAKLKAGQTRTALEMTLDDLFGAVEQEWQEQALCAQTDPEAFFPEKGGSTREAKRICQGCPVRDECLEFALEHDERFGIWGGLSERERRRLKREIS
>NZ_CP010451.1|WP_040967093.1|839444_840533_+|NDP-sugar-synthase
MTLTDNSKNVDAVILVGGKGTRLRPLTVNTPKPMLPTAGHPFLTHLLARIKAAGITHVVLGTSFKAEVFEEYFGDGSEMGLEIEYVVEDQPLGTGGGIRNVYDKLRYDTAIVFNGDVLSGADLSSILDTHREKEADLTMHLVRVANPRAFGCVPTDQDGRVSEFLEKTEDPPTDQINAGCYVFKKELIEQIPAGRVVSVERETFPQLLEEGKRVFGHVDASYWRDMGTPSDFVRGSADLVRGIAYSPLLEGKTGESLVDASAGVRDGVLLLGGTVVGRGTEIGAGCRVDNTVIFDGVTIEPGAVIENSIISSGARIGANAHISGCIIGEGAQVGARCELNAGMRVFPGVVIPDSGIRFSSDQ
>NZ_CP010451.1|WP_040967092.1|838399_839272_+|glycosyltransferase-family-2-protein
MITVTYSPGKYLASFLDSLPGATSRDTHVVMADNGSVDGVPEQAAASRSNVEFLSTGGNLGYGTAINIAARSLRARREAGEIDGEFFLVSNPDVVFDEDSIDQLLECAKRHPEAGAVGPLIREADGSAYPSARAVPTLANGIGHALLGAVWKSNPWSAAYRDDEDMDTERTAGWLSGSCLLLRWDAFDRVGGFDERYFMYMEDVDLGDRLVRAGFTNVFCPSAQIIHAKGHVAGKNPENMLPAHHESAYRFQADRLAKPWQAPIRLALRVGLKLRAGVAVGVSKMRTKAS
>NZ_CP010451.1|WP_040967091.1|836491_838051_-|LCP-family-protein
MTEKYRPVRDIKPAPAAMQSTKQAGHPVFRSVVAFVSVLVLLVSGLGYLAVGKVDGVASGNLNLGGGRGIQDGNAADGATDILLVGSDSRSDAQGNTLTEEELAMLRAGDEENDNTDTIMVIRVPNDGSSATAVSIPRDTYIHDDDYGNMKINGVYGAYKDARRAELMDQGFTNESELETRAKDAGREGLIEAVSDLTGITVDHYAEVGLLGFVLLTDAVGGVEVCLNNAVDEPLSGANFPAGRQTLGGSDALSYVRQRHDLPRGDLDRIVRQQSYMASLVNQVLSSGTLTNPAKLSALADAVTRSVVIDEGWEIMSFATQLQNLAGGNVTFGTIPVTSIDGTGDYGESVVTIDVNQVHAFFQEALGEAEPAPEDGSDDQSADQAPDLSEVEVHVLNASYTEGLASGIAAHLQEMGYTISETGNAAEGLYYESQILAAEADNEKALAISEALGGLPIVANSSLDDNTVIVVSAGDYAGPTAEANAVITSSTVGQPGADVGAPIESPEFDAGGDGPRCVN
>NZ_CP010451.1|WP_040967090.1|833480_836369_-|DEAD/DEAH-box-helicase
MSESGALSSTDSLSPGVTIEVRDEIWLVTHVARSTDGFRVKARGLSDYVRDHEATFFTALDKDLRVIDPTQVTVSLDDSSNYRRTRLWLEATMRKTPVPLYQESLSVADQMLADPLEYQLAAVRKALSSANLRPRVLIADAVGLGKTLEMGMILAELIRRGRGERILVVTPRHIMEQFQQEMWTRFAIPLVRLDSVGIQQVRQKLPASRNPFTYFPRVIVSMDTLKSPKYRAQLEKVHWDAVVIDEIHNATNAGTQNNELARTLAPTAEALILASATPHNGDPESFKEILRLLDPTSVMPDGTIDAEAAQRLIIRRHRNSPEVSGYVGEKWAPRNEPQNFLVAASKEENGVAAELNHVWISPGASNPIKDRLFPWTLVKAFLSSPAALGETVSNRLKKASAPEEKRALETLSRLNSAITPQTSQKYQSLLKYLGDIGVKKNSDTRVVIFSERVATLHWLQENLTRDLKMPANSIAVMHGRLPDQEQMRLVDEFKKTDSPIRIMITGDVASEGVNLHTLCHNLVHYDIPWSLIRIQQRNGRIDRYGQTHNPSIVTFLLDPAEDSKVGEVHVLERLMEREHEAHSLLGDAASLMGKHSERLEEETIREVLRGAQNFNDAVADPAVVLENPAGLDDIDWLLAQIAQADAETEAKAATEAENQTAPDAASNSTQHAQRRLYAQESSFLYDCLLEGFNNVPEDSINRGGVGFKKHDNDIVELTPTDDLRRRLDFLPQDYVAARKVKEDLLLASTLMRGQERLNAARTGEDGSTWPSAHYLGPLHPVISWAADRALATMPRSEIPAASGKVTEPTVLLMSTLSNRRGQIVSRSFVASSGPFDTEVLSDPIQWLHSIGLDETAINPGTAELPDDVEQLISLAVQAARGEIRPLMIAARAQAQTRVEHWAKRAEAWNNKRSGAASTSRTARTAKLIEEQQKLSNALEPDRELIRPLAVILPQSATLNIEV
>NZ_CP010451.1|WP_040967096.1|846598_847384_-|hypothetical-protein
MKTETRRALVFIVAGCLAATALGFMVWQMSSPSRPTSDIATSTTTSTTQTQARYDSPGNTETQEAEPDLENQTLAPINTEDPYLPPNAFVRPDNGRSSGSTPSGSSPTTTSRVSSPSSAGSASPTQITSRSNEPSEPDDESTATTQPSSPDRPTEPTNPVDPTGPSEPTEPTDPIETTDPIETTDPVSPSTPPTSDDSTSTPQPDESDTPPTDFVEEPTAPLNPDQPAGSTTDATPNATPSAPADTTSNSVANSVEPTATS
>NZ_CP010451.1|WP_003858196.1|847627_847981_+|hypothetical-protein
MGAWDDAILTEEVNVDFLDEISELDTQDILEALEDACLLVVNQDNATEDEHLNGQAAATIAAIMFGAPYSAGQVLENYPFIRELVGEGSEALRGAAAQVLEEADVEYDLEAYLEALN
>NZ_CP010451.1|WP_040967097.1|848091_849528_+|adenosylhomocysteinase
MAQVMDFKVADLSLAEAGRHQIRLAEYEMPGLMQLRKEFADEQPLKGARIAGSIHMTVQTAVLIETLTALGAEVRWASCNIFSTQDEAAAAIVVGSGTVEEPAGVPVFAWKGESLEEYWWCINQIFSWGDELPNMILDDGGDATMAVIRGREYEQAGLVPPAEANDSDEYIAFLGMLREVLAAEPGKWGKIAEAVKGVTEETTTGVHRLYHFAEEGVLPFPAMNVNDAVTKSKFDNKYGTRHSLIDGINRATDMLMGGKNVLVCGYGDVGKGCAEAFDGQGARVKVTEADPINALQALMDGYSVVTVDEAIEEADIVITATGNKDIISFEQMLKMKDHALLGNIGHFDNEIDMHSLLHRDDVTRTTIKPQVDEFTFSTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFADQTIAQIELFQNEGQYENEVYRLPKVLDEKVARIHVEALGGQLTELTKEQAEYIGVDVAGPFKPEHYRY
>NZ_CP010451.1|WP_003858194.1|849527_850139_+|dTMP-kinase
MIVSIEGIDGAGKNTLVSALTQVIDAKVLAFPRYETSIHAQLAAEALHGRMGDLTDSAYAMATLFALDRHFAIDDLNAPGVVLLDRYVASNAAYTAARLLDDDAPRWVADLEFGRLGLPRPTLQVLLDTPAEVAQDRARRREALDSARARDRYESDSALQQRTAEHYRRLAADNWESPWIVVAPDEDPGHVAQRIVEFLGTIN
>NZ_CP010451.1|WP_038583063.1|850163_850844_+|response-regulator-transcription-factor
MSQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMNGIDICRLIRQESSVPIIMLTAKTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRATVDEPSEILEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLLELARKPQQVFTREELLGKVWGYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHND
>NZ_CP010451.1|WP_003863563.1|850943_852443_+|HAMP-domain-containing-histidine-kinase
MLGSIFTASAVVMILLGLGMLTVFTQRLVDQKIDIASSEIDRARVIVEEQITASGASTSVQARVNSARAALSSLGTSGSTETNAAYDPVVLVNNDDLVVSPEGYQIPERLRYFVSENQVSYQFSSIDQGDGSSYQALIIGTPTESDIPNLQVYLVFSMESDESSLALMRGLLSAALLIVVVLLVGIAWLATQQVTAPVRSASRIAERFAQGKLRERMVVEGEDEMARLAVSFNAMAESLSAQITKLEEYGNLQRQFTSDVSHELRTPLTTVRMAADLIADSEDELSPGARRASQLMTRELDRFESLLSDLLEISRHDAGVAELSTALHDVRIPVRSALEQVQHLATELDVELLVDLPEEAINIQGDSRRIERIIRNLLANAIDHSKGLPVELKVADNEDAVAIVVIDHGVGLKPGQDELVFNRFWRADPSRVRHSGGTGLGLAISREDAMLHGGNLDAAGTIGVGSIFRLVLPKEPHGNYREAPIPLIAPETPWEGEQQ
>NZ_CP010451.1|WP_040967098.1|852439_854146_+|MtrAB-system-accessory-protein-LpqB
MSKISTKLKTLTAVLSVTTLVAGCSTLPQNTDPQVLRSFSGSQSTQEIAGPTPNQDPDLLIRGFFSAGAYPTQQYEAAKAYLTEGTRSTWNPAASTRILDRIDLNTLPGSTNAERTIAIRGTQVGTLLSGGVYQPENAEFEAEITMRREDGEWRIDALPDGILLERNDLRNHYTPHDVYFFDPSGQVLVGDRRWLFNESQSMSTVLMALLVNGPSPAISPGVVNQLSTDASFVGFNDGEYQFTGLGNLDDDARLRFAAQAVWTLAHADVAGPYTLVADGAPLLSEFPTLTTDDLAEYNPEAYTNTVSTLFALQDGSLSRVSSGNVSPLQGIWSGGDIDSAAISSSANVVAAVRHENNEAVLTVGSMEGVTSDVLRSETITRPTFEYASSGLWAVVDGETPVRVARSATTGELVQTEAEIVLPRDVTGPISEFQLSRTGVRAAMIIEGKVYVGVVTRPGPGERRVTNITEVAPSLGEAALSINWRPDGILLVGTSIPETPLWRVEQDGSAISSTPSGNLNAPVVAVASSATTIYVTDSHAMLQLPTADNDIWREVPGLLGTRAAPVVAY
>NZ_CP010451.1|WP_040967099.1|854145_854736_+|ComF-family-protein
MELFFPRACGGCGAPGASLCSDCQRVWRKPPTLARLDLDVPVWTLSPYDGPHRNVLIALKEHGRSDLVAFVGAVVGASISYLAAQGEIEHEITLVPAPTRATSRRRRGGDPVERVCNASRLSTFPCLQISSRTPDSVGQTAQQRRLNMRVELVRQPRGSVLIIDDVVTTGATISASANVLRAAGVQVRGALTYCQA
>NZ_CP010451.1|WP_003858182.1|854879_855545_+|ribosome-associated-translation-inhibitor-RaiA
MTTPAENNTLSPETKVSITGRNVEVPDHFAERVNTKLAKIERLDPTLTFFHVELQHEPNPRRADESDRIQITATGKGHIARAEAKEDSFYAALETALAKMERSLRKVKARRSISRSGHRAPLGTGEVGAQLVAESQEARGADELGKYDVDPYADKVDDVMPGQVVRTKEHPATPMSVDDALSEMELVGHDFYLFVNEETNQPSVVYRRHAFDYGLISLSDA
>NZ_CP010451.1|WP_040967100.1|855683_858221_+|preprotein-translocase-subunit-SecA
MFGLSKVLRVGEGRAVKRLHKIADQVIALEEKFANLTDEELKAKTAEFKERIAGGEGLDEIFLEAFATAREASWRVLGQKHYPVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEMVGRVHRYLGLEVGVILSDMRPDERRKAYTADITYGTNNELGFDYLRDNMARSLSDLVQRGHNYAIVDEVDSILIDEARTPLIISGPVDGTSQFYNVFAQIVPRMTKDVHYEVDERKKTVGVKEEGVEYVEDQLGIDNLYAPEHSQLVSYLNNAIKAQELFTRDKDYIVRNGEVMIVDGFTGRVLAGRRYNEGMHQAIEAKERVEIKNENQTLATVTLQNYFRLYTKLAGMTGTAETEAAELNQIYKLDVIAIPTNRPNQREDLTDLVYKTQEAKFAAVVDDIAERTEKGQPVLVGTVSVERSEYLSQLLTKRGIKHNVLNAKHHEQEAQIVAQAGLPGAVTVATNMAGRGTDIVLGGNPEILLDIKLRERGLDPFEDEESYQEAWDAELPAMKQRCEERGDKVREAGGLYVLGTERHESRRIDNQLRGRSARQGDPGSTRFYLSMRDDLMVRFVGPTMENMMNRLNVPDDVPIESKTVTNSIKGAQAQVENQNFEMRKNVLKYDEVMNEQRKVIYSERREILESADISRYIQNMIEETVSAYVDGATANGYVEDWDLDKLWNALEALYDPSINWTDLVEGSEYGKPGELSAEDLRTALVNDAHAEYAKLEEAVSAIGGEAQIRNIERMVLMPVIDTKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQKEGGDMFNGMKDGIKEETVRQLFLLRKQFIKQDAEVAD

Crispr_ID: NZ_CP010451_7

• CRISPR_ID: NZ_CP010451_7
• CRISPR_location: 2803227-2803325
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010451_7

Consensus_repeat	Method
TGGTCGGGCCACGCGTTTGTGGTGGA	CRISPRCasFinder

spacers of NZ_CP010451_7

>7.1|2803253|47|NZ_CP010451|CRISPRCasFinder
TTTTTGCACCTTGCAGCCAGTTTGATGCGAAAATTCGTTCGGTTTAA

CRISPR arrays and Neighbor proteins around NZ_CP010451_7

CRISPR arrays

The CRISPR arrays of NZ_CP010451_7

>merge|NZ_CP010451|7|2803227-2803325|CRISPRCasFinder
TGGTCGGGCCACGCGTTTGTGGTGGATTTTTGCACCTTGCAGCCAGTTTGATGCGAAAATTCGTTCGGTTTAATGGTCGGGCCACGCGTTTGTGGTGGA

>NZ_CP010451|7|7|2803227-2803325|CRISPRCasFinder
TGGTCGGGCCACGCGTTTGTGGTGGA	TTTTTGCACCTTGCAGCCAGTTTGATGCGAAAATTCGTTCGGTTTAA
TGGTCGGGCCACGCGTTTGTGGTGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010451.1|WP_040967915.1|2805061_2806228_+|Na/Pi-cotransporter-family-protein	unknown	unknown	gnl|CDD|224202
NZ_CP010451.1|WP_003862899.1|2795364_2795640_+|hypothetical-protein	unknown	unknown	gnl|CDD|181179
NZ_CP010451.1|WP_003853704.1|2797062_2798193_-|glutamate--cysteine-ligase	unknown	unknown	gnl|CDD|237408
NZ_CP010451.1|WP_040967911.1|2798942_2799155_-|DUF3263-domain-containing-protein	unknown	unknown	gnl|CDD|378688
NZ_CP010451.1|WP_040967914.1|2803471_2804668_-|multidrug-effflux-MFS-transporter	unknown	unknown	gnl|CDD|340878
NZ_CP010451.1|WP_003853711.1|2795640_2796021_+|cation:proton-antiporter	unknown	unknown	gnl|CDD|183613
NZ_CP010451.1|WP_011897935.1|2801573_2803076_+|cardiolipin-synthase	unknown	unknown	gnl|CDD|234967
NZ_CP010451.1|WP_074495927.1|2814524_2814788_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_040967913.1|2800775_2801567_+|exodeoxyribonuclease-III	unknown	unknown	gnl|CDD|197320
NZ_CP010451.1|WP_003853708.1|2796456_2797056_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP010451.1|WP_074508401.1|2807068_2807839_-|multidrug-ABC-transporter-permease	unknown	unknown	unknown
NZ_CP010451.1|WP_003853702.1|2798271_2798937_-|LytR-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379163
NZ_CP010451.1|WP_040967916.1|2806224_2807067_-|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl|CDD|223461
NZ_CP010451.1|WP_034983299.1|2809471_2810860_+|membrane-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_003862877.1|2811884_2814353_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|319004
NZ_CP010451.1|WP_003862879.1|2810860_2811895_+|glutamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408
NZ_CP010451.1|WP_003862894.1|2799170_2799752_+|peptide-deformylase	unknown	unknown	gnl|CDD|237227
NZ_CP010451.1|WP_074508400.1|2808773_2809277_-|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239217
NZ_CP010451.1|WP_040967912.1|2799741_2800749_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP010451.1|WP_011015345.1|2807819_2808752_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213235

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010451.1|WP_040967915.1|2805061_2806228_+|Na/Pi-cotransporter-family-protein	gnl|CDD|224202	COG1283, NptA, Na+/phosphate symporter [Inorganic ion transport and metabolism].	5.2321e-95
NZ_CP010451.1|WP_003862899.1|2795364_2795640_+|hypothetical-protein	gnl|CDD|181179	PRK07948, PRK07948, putative monovalent cation/H+ antiporter subunit F; Reviewed.	4.78942e-38
NZ_CP010451.1|WP_003853704.1|2797062_2798193_-|glutamate--cysteine-ligase	gnl|CDD|237408	PRK13517, PRK13517, glutamate--cysteine ligase.	0
NZ_CP010451.1|WP_040967911.1|2798942_2799155_-|DUF3263-domain-containing-protein	gnl|CDD|378688	pfam11662, DUF3263, Protein of unknown function (DUF3263). This family of proteins with unknown function appears to be restricted to Actinobacteria.	9.49222e-26
NZ_CP010451.1|WP_040967914.1|2803471_2804668_-|multidrug-effflux-MFS-transporter	gnl|CDD|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.42022e-100
NZ_CP010451.1|WP_003853711.1|2795640_2796021_+|cation:proton-antiporter	gnl|CDD|183613	PRK12592, PRK12592, putative monovalent cation/H+ antiporter subunit G; Reviewed.	2.61795e-74
NZ_CP010451.1|WP_011897935.1|2801573_2803076_+|cardiolipin-synthase	gnl|CDD|234967	PRK01642, cls, cardiolipin synthetase; Reviewed.	1.54843e-117
NZ_CP010451.1|WP_040967913.1|2800775_2801567_+|exodeoxyribonuclease-III	gnl|CDD|197320	cd09086, ExoIII-like_AP-endo, Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases. This subfamily includes Escherichia coli ExoIII, Neisseria meningitides NExo,and related proteins. These are ExoIII family AP endonucleases and they belong to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds. AP endonucleases participate in the DNA base excision repair (BER) pathway. AP sites are one of the most common lesions in cellular DNA. During BER, the damaged DNA is first recognized by DNA glycosylase. AP endonucleases then catalyze the hydrolytic cleavage of the phosphodiester bond 5' to the AP site, and this is followed by the coordinated actions of DNA polymerase, deoxyribose phosphatase, and DNA ligase. If left unrepaired, AP sites block DNA replication, and have both mutagenic and cytotoxic effects. AP endonucleases can carry out a variety of excision and incision reactions on DNA, including 3'-5' exonuclease, 3'-deoxyribose phosphodiesterase, 3'-phosphatase, and occasionally, nonspecific DNase activities. Different AP endonuclease enzymes catalyze the different reactions with different efficiencies. Many organisms have two AP endonucleases, usually one is the dominant AP endonuclease, the other has weak AP endonuclease activity. For example, Neisseria meningitides Nape and NExo, and exonuclease III (ExoIII) and endonuclease IV (EndoIV) in Escherichia coli. NExo and ExoIII are found in this subfamily. NExo is the non-dominant AP endonuclease. It exhibits strong 3'-5' exonuclease and 3'-deoxyribose phosphodiesterase activities. Escherichia coli ExoIII is an active AP endonuclease, and in addition, it exhibits double strand (ds)-specific 3'-5' exonuclease, exonucleolytic RNase H, 3'-phosphomonoesterase and 3'-phosphodiesterase activities, all catalyzed by a single active site. Class II AP endonucleases have been classified into two families, designated ExoIII and EndoIV, based on their homology to the Escherichia coli enzymes ExoIII and endonuclease IV (EndoIV). This subfamily belongs to the ExoIII family; the EndoIV family belongs to a different superfamily.	2.42982e-104
NZ_CP010451.1|WP_003853708.1|2796456_2797056_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.28371e-06
NZ_CP010451.1|WP_074508400.1|2808773_2809277_-|NUDIX-hydrolase	gnl|CDD|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	3.64468e-16
NZ_CP010451.1|WP_003853702.1|2798271_2798937_-|LytR-C-terminal-domain-containing-protein	gnl|CDD|379163	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator. This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family.	0.0014775
NZ_CP010451.1|WP_040967916.1|2806224_2807067_-|PhzF-family-phenazine-biosynthesis-protein	gnl|CDD|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	3.57913e-101
NZ_CP010451.1|WP_003862877.1|2811884_2814353_+|serine/threonine-protein-kinase	gnl|CDD|319004	pfam16918, PknG_TPR, Protein kinase G tetratricopeptide repeat. This domain is found at the C-terminus of protein kinase G and contains a tetratricopeptide repeat (TPR).	3.40496e-95
NZ_CP010451.1|WP_003862879.1|2810860_2811895_+|glutamate-ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.00674e-75
NZ_CP010451.1|WP_003862894.1|2799170_2799752_+|peptide-deformylase	gnl|CDD|237227	PRK12846, PRK12846, peptide deformylase; Reviewed.	6.52209e-77
NZ_CP010451.1|WP_040967912.1|2799741_2800749_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.6306e-10
NZ_CP010451.1|WP_011015345.1|2807819_2808752_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	1.37782e-94

Protein sequences

>NZ_CP010451.1|WP_011897935.1|2801573_2803076_+|cardiolipin-synthase
MIFQINLESWQTVGLIIDYTIKIIAIGYVPEGRRPSSSTAWLLAILLLPYVGLPLFLLMGSPYINRRRHRIQQEINDLIEDVHDDVPDIPTGMDVSAEVESVIKLNRRLTRMPAVTGGNNGFYSDYRESLKRMTAAIDEAEEYIYVEIYIMAWDSYTQPFFAALERAHNRGVKVRLLFDHVGSWKYPGYHRLKKELNRMGFAWYLMLPLQPWRRRFRRPDLRNHRKMLIIDGHTAFMGSQNLIAPSYLQKKNIKLGREWKDLMVELTGPIVSSMEMIFAGDWYVESNEALDIRDHAEAHGYIGNTQKDSATNLVQLIPSGPGYTTEPNLRMFNSIVHHAKERLILCSPYFIPDESLLEAVTSACYRGVTVELFVSEQADQFAIDHAQSSYYQALLEAGVKIYQFPKPDVLHTKYMIADPDDTTGNEALGVLGSSNLDIRSFGLNYEISLMIAKGNLIHELNALTDRYRTVSLKLTLDKWNQRSWRRRYVDNVMRLTSALQ
>NZ_CP010451.1|WP_040967913.1|2800775_2801567_+|exodeoxyribonuclease-III
MRIVNWNVNSARTRVDRMVDFLLRHDVDVLAVQETKCKDEQFPTERFTEIGYEVAHFGLNQWNGVAIISRVGIENVETHFPAQPGFNKDITKEQSIEARAIGARCGGVQVWSLYVPNGREIADPHYDYKLRWLFSLRNYVIDTLEYRPEEKLVLLGDFNIAPTDIDVWDIAAFEGKTHVTEPERAAFDGLIEAGLKETTPGPGTYTYWDYKGARFLKGEGMRIDFQLASPALAATAGKTFVDVEERSGTGASDHAPVIVDYKV
>NZ_CP010451.1|WP_040967912.1|2799741_2800749_+|GNAT-family-N-acetyltransferase
MTPSLPRFRSQKPAVGDRVVARRRIPGANVHWTDVIGHVIGVDPLVVRPQSVGGMPSDAEEIVIPDDQLEVIKILSPRTIRNSDIRAVEVATAKAFPGLVNEWHDGWLLRAGDGIAERSNSASPLGPSVGFEPVPMEDISRFYARHDLPVKLHIPERIGRPAQKMVDADPKQWVLGPEILVMTKSLDHMESHELPGGLEFSVDKQPDQEWLGMYHFRGQALPAHALELLRTQIEGHMGFGRLTTPAGQTVAITRATITAAEERIFLGYSAVEVDPAFRRQGLGTALGSRIQEWGAEQHAQEAYLQVVAHNEAGIGLYQKLGFSEHHRHRYAERKF
>NZ_CP010451.1|WP_003862894.1|2799170_2799752_+|peptide-deformylase
MTVRPIVIHGDPVLHNPTQLVTEDVSELQELIADMYETMDVANGVGLAANQIGVSKRIFVYDCPDDEGVMHKGCFINPVLETSEIPETMPADDGSDEEGCLSVPGEGFPTGRAHWAKVTGLNEKGEEVSVEAEGFLARCFQHEVGHLDGFLYTDVLIGRWKRMAKKAIKANGWTEPGLTWMPGEDEDPFGHDA
>NZ_CP010451.1|WP_040967911.1|2798942_2799155_-|DUF3263-domain-containing-protein
MLSADDLTLLEFEAHAPHAIGAKEEAIRATFGISPVRYYQRLNVIIDTPEAMKANPTLVSRLRRRAGKID
>NZ_CP010451.1|WP_003853702.1|2798271_2798937_-|LytR-C-terminal-domain-containing-protein
MTSDMQNSPQHSATPSEEKQGGLPMRGLAMILIAVAVLLAAWALWSMQGKDDTSTTSAGQTQSTETNAGTIAESSGSSDSEQASAEPGTSEETSAEQPAADGEAANAAGTAAAGGASSANGNSTPVNTLYVLNNSTVPQLAARVADSLSGDYQKVESGNLPDTIIPQNTVYFTAGNTEAEKAARELADRVSGVAMERSDALPTETEGKDALVLVLVQDVAL
>NZ_CP010451.1|WP_003853704.1|2797062_2798193_-|glutamate--cysteine-ligase
MGIEFKRSPRPTLGVEWEIALVDPETRDLAPRAAEILEIVAKNHPEVHLEREFLQNTVELVTGVCDTVPEAVAELSHDLDALKEAADSLGLRLWTSGSHPFSDFRENPVSEKGSYDEIIARTQYWGNQMLIWGIHVHVGISHEDRVWPIINALLTNYPHLLALSASSPAWDGLDTGYASNRTMLYQQLPTAGLPYQFQSWDEWCSYMADQDKSGVINHTGSMHFDIRPASKWGTIEVRVADSTSNLRELSAIVALTHCLVVHYDRMIDAGEELPSLQQWHVSENKWRAARYGLDAEIIISRDTDEAMVQDELRRLVAQLMPLANELGCARELELVLEILERGGGYERQRRVFKETGSWKAAVDLACDELNDLKALD
>NZ_CP010451.1|WP_003853708.1|2796456_2797056_-|alpha/beta-hydrolase
MVESQHIIFIPESQQTPDEFTEVVNEIPAGIKPRIVPWSGSVSAGVQAVESILDREEIRRVILVGAGTGAGVALEIAKNQPRRVERLVLDSPLVTFDEKQLKGMSTALKMMPGFFFRKKNKKDLLQQVEEARTAVPMGFSEITMPTLIIRGSAAKAGIDSDLEKQIPSARATTIIGANWLTYTTHGRQTGAAIAEFLAQ
>NZ_CP010451.1|WP_003853711.1|2795640_2796021_+|cation:proton-antiporter
MTLQLFTDIVSLVFILSGAFLSFSASIGLIRFKDTMSRVHAMTKPQTTGLILTVVGAIIRILGHEHFDQSQRSDLGVLVLLVLFALLTSPVTAQRVGRVSRREGLYGAKDDMSDNQAPAELKPKKS
>NZ_CP010451.1|WP_003862899.1|2795364_2795640_+|hypothetical-protein
MDNTLYTAGLTIAAAFFMLSFIFTIYRIIVGPNSIDRLLGLDGTVSMIQCSMATYICWTLDTTVTNFMMVIALLGFISSVSVARFRKRDGA
>NZ_CP010451.1|WP_040967914.1|2803471_2804668_-|multidrug-effflux-MFS-transporter
MQKKQQLSTALIMGLALLSASSALATDMYLPAMPGIAEDLGTTAPMVQLTLSSFMAGMAIGQLIIGPLSDQLGRKGLLVAGAVAALVASVVCALAPSISVLVIARLVQGLGGGACVVIARAIVPDLERGQKAAHAFALLMIIQGIAPVVAPLIGGVLVGPFGWRGIFWALALVNFAQLLVALLQIKESKPVEERTAVGLGGMLSNYVFVLKNPQFLAYVFTLGLSFGAMFSYISASPFVLQNQMGIPVLLYSIIFGVNAFGLIVGGMVNRRLLQRIHPHRIMQTVLASFTVLCALLLIEVLFINWIPLFLLLLFLIVSHIPMVMANATALGTEVVRSRAGSGSAILGFVQFTMGALVSSLVGLGSDKALTMGIAMTACALLACGCAYLAGRKGIPEMK
>NZ_CP010451.1|WP_040967915.1|2805061_2806228_+|Na/Pi-cotransporter-family-protein
MLLSGWGKFVRWLLVLLSILVIIIGINLILDGVYGFGTFSTTQMYQVAKDPLIGVLIGILATALVQSSTTTTTLTVTAVGTGIVSVPVAIPIILGANIGTTITAMLVAFSYMGERREFKRAFTVAAMHVWFNVLVILVLFVVELLFHPFRTISGAIATEITLTTGGSLPTSDVMTKIFDPPTQLLGMNGLIGSIGNPSISAIVCLVVGTILILISVRAMSSQIRTITAATVTSIMDKVINPENSPKATILSNFWSFILGVLFTLMVTASSVTVASMQPVAVSGVVKQKPLLGVILGANVGTTVTAMFATFAIVSDQGEFAIQAALIHLIVNFTGALLVLCIPQLANVIIHLAEKTANLTARSYSITLAIIVTAYVLFPSAVLMIYFFI
>NZ_CP010451.1|WP_040967916.1|2806224_2807067_-|PhzF-family-phenazine-biosynthesis-protein
MPSKISRPYYQVDVFSSEPFMGNPLAVIADADDLSAEQMARIARWTNLSETTFLLKPTQEGADYRVRIFTPTGELPFAGHPTLGTAHVFRELHGEQGTQLVQECVAGLVAVRAIDGPASGLAFQAPPTLKDGPLDASDLDAACEALGISPDFIRAHQWVDNGPGWAVVELPSAQHVLDLEPDFSAHPTLKLGVIGAYPEGAPHAFEVRAFAPGIGEDPVTGSLNASIAQWLHRDGRAGEGYLASQGTAIGRAGEIHISIESDVIWVGGSVTTIFQGTAEF
>NZ_CP010451.1|WP_074508401.1|2807068_2807839_-|multidrug-ABC-transporter-permease
MWTTMINTIRSEWTKLVTTKSFWWTTALILVFSLGYAALTGSLATGESFASLFLLAGSTVTGLYLLGFVVIMIQSIMMFTTEFRFGYQTQTFLATPKRWVVAVSKWLLYLVFAVVLTFITVILCFYLAKALASDTASSTLVVWEDTQARRIMWQYPLAAALLVTFCSGIALLLRQTAGAVALVLMWHFAIENLLSFLPRIGEYVGKYGPFTNLYAFITDYQSIDPGWSTTMGAVYFGAWAFVLFALGIVFLEKKDA
>NZ_CP010451.1|WP_011015345.1|2807819_2808752_-|ABC-transporter-ATP-binding-protein
MINVEGLTKQYGQVRAVDDLSFEVKPGIVTGFLGPNGAGKSTTMRLILGLDNPTAGHATIEGQPYRSLKNPLTKVGALLDAKATHPNRTAENHLKWIARANGLSTKRVDEVLTLVGLTGVASKKTGGFSLGMGQRLGLAAALLGDPEYLILDEPVNGLDPEGIHWVRTLLQNIAKQGRTVLVSSHLLSEMAQTAEHLIVIGRGKLVADMPMHEFVRSHSASTVVVRAAVPGALENALKEAGVAFNTAPDESGRMTYRIDGSTTDDIGRLAFERGIALLELSETRASLEEAFLETTGEAVQYQAGSVDNND
>NZ_CP010451.1|WP_074508400.1|2808773_2809277_-|NUDIX-hydrolase
MDTMKGDGDGWAAAPNGGAVWGKNGAAGLLLVADKQMLMQHRAAWTNNGDTWALPGGARDSHETAAESALREAFEETGILPDDVKVLDSIVTAGPFPADPERPELAGNWTYTTVIARTKTGETLETTANEESLELRWVDIAAVDSLALMPAFAKAWPSLRKLLNTTE
>NZ_CP010451.1|WP_034983299.1|2809471_2810860_+|membrane-protein
MDTDDSPDHWLDPLTEKDTSKRTLVNSIVQETFGQPIFVARKIWAFVNTSPGRMTLMTIIISIAIFAAGYAMSVSSDTRQSNLDDLITNAEPVSYNAHVLYTSLSVADTTATTGFVQAGVEGPVNRVKYHTAIDRAAVAATHTAASADSSNEHLMELVLEIQRQLPVYTGLVETARTNNRAGNPVGVAYMSEASAMMRNEILPMASELYNLTSRAVSDQQRSVTGPQWFPLSGLLAALAMLIVAQWWLMRITRRRINKGFALATVMMMTATLWVSAANWATWQAGTKGFEEASGPLNSMTTARIYAQQTRTTETLSLVRRQSIQGSGTGFTATINQIKRALDEYETTAQSQTPEHQQLITAIRNAIAAWTADHDEFTVLLASGEYNGAVSAVLNKDEEGQTSFDELDTALAELIADSRSSMRSYIQSGLQATELVSVMVMLLSVVSVLALWVGIRPRLQEYL
>NZ_CP010451.1|WP_003862879.1|2810860_2811895_+|glutamate-ABC-transporter-substrate-binding-protein
MHAFRRPPPLTTRVGAALLAATLLASCTPTPVEPAETLTALDPDAGPPLPPDSSIEAPGEKEPIVEAIENWPGSLRPDDLTPEERVPGIVNRGRIIVGVDQSQNLLSFRDPVTGELRGFEVELAREISRDIFGDPNKVDFRFVGSSDRLRSLDQGDVDIVIRSVTITDERAKLVEFSTPYLRTQTRMLTMESSGITSIADLPGHTICVTDGSTSLQRARTIAPEASILKTRNWSDCLMALQQHQAQVILGDDVILSGIAAQDPYTKILDTSLDSHSYGVAAASTTAETDSSGLIRQVNYTIERIRTDRMWWTMFDDWFGPYLWSYGPPQLQYMPEEEGTENDEG
>NZ_CP010451.1|WP_003862877.1|2811884_2814353_+|serine/threonine-protein-kinase
MKDNEDFDPDSPATEAVAFNPFDDDDEDDSPATSAVAFNPFEDDDDDDEFQGEGLEFLLRDLDNLRATQGQMVVEQPAVEDSLGSASAHTETTAASLRPRPEVDPSERSRRQAISLFRERRRVRRQSRPVADGMVELPFITPKPEDELLIDPEKKRKPGVAAPQLVAGDIVAEQYEVLGVIAHGGMGWIYLANDRNVSGRIVVLKGMMAQSSVQDQGTAEAEREFLADITHPGIVKAYNFIDDPRVPGGFIVMEYVNGPSLKDRCKAQPDGVLRVDLAIGYILELLPAMDYLHQRGVVYNDLKPENVIATEDQVKLIDLGAVTGIGAFGYIYGTKGFQAPEVATDGPSISSDIFTIGRTLAALTMPLPVEDGVLAPGIPSPKNSPLLRRHLSFYRLLQRATADDPQHRFHNVSELRTQLYGVLREILAVRDGKQYPPQHSLFSPQRSTFGTKHLVFRTDRIIDGIERQARITAPEIVSALPVPLIDRTDPGARMLSGSSYAEPSETLETLRNSMEDEQYRQSIEIPLGVVRALLDLGFTTEARQWLETLEGRIGDDWRHKWFSGITYLLLDDYATAQVFFNHVLTILPGEAAPKLALAAVDELILQQIGAESTAYLTPDIVSATATLSKDFEDLDASAFESLSDTWSHISSDPHVVRFHSLRLYALVWATNPTTVSSAFGLARQLMAENQIELAVQALDKLPQSSTHYRMATLTTILLLVSSNLSESRIRRAARRLTEIPTNEPRFNQIKIAIMSAGLSWLRERKLKASASANPLFEYPFSQKGLRTGISEALRIQARSAPFPHHRYALVDMANAVRPLSWF
>NZ_CP010451.1|WP_074495927.1|2814524_2814788_-|hypothetical-protein
MWWIFAFLRGETARIHHRSQFSFGTWWILALELHRNRLLAPRPLGVANFRPHRTLKGRFWSKICSNTLLLCKSSFDLSKSRQSVTRS

Crispr_ID: NZ_CP010451_8

• CRISPR_ID: NZ_CP010451_8
• CRISPR_location: 3090994-3091164
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP010451_8

Consensus_repeat	Method
GCCTTGGTTTCCACCGAA	CRT

spacers of NZ_CP010451_8

>8.1|3091012|27|NZ_CP010451|CRT
TCCGCCCTGGTTGCTTTGCTGCTGGTT
>8.2|3091057|39|NZ_CP010451|CRT
GCCGCCAGAGTTCTGGTTGCTGAATCCACCTTGCTGGTT
>8.3|3091114|33|NZ_CP010451|CRT
GCCACCACCTTGGTTGCCGCCACCGTAGTTTCC

CRISPR arrays and Neighbor proteins around NZ_CP010451_8

CRISPR arrays

The CRISPR arrays of NZ_CP010451_8

>merge|NZ_CP010451|8|3090994-3091164|CRT
GTTTTGGTTTCCACCAAATCCGCCCTGGTTGCTTTGCTGCTGGTTGCCTTGGTTTCCACCGAAGCCGCCAGAGTTCTGGTTGCTGAATCCACCTTGCTGGTTGCCTTGGTTTCCACCGAAGCCACCACCTTGGTTGCCGCCACCGTAGTTTCCGCCAGAGTTTCCACCGCG

>NZ_CP010451|8|4|3090994-3091164|CRT
GTTTTGGTTTCCACCAAA	TCCGCCCTGGTTGCTTTGCTGCTGGTT
GCCTTGGTTTCCACCGAA	GCCGCCAGAGTTCTGGTTGCTGAATCCACCTTGCTGGTT
GCCTTGGTTTCCACCGAA	GCCACCACCTTGGTTGCCGCCACCGTAGTTTCC
GCCAGAGTTTCCACCGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010451.1|WP_003861194.1|3092213_3092405_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_011015536.1|3080914_3081232_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_074508484.1|3097246_3098191_+|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NZ_CP010451.1|WP_040968050.1|3093907_3096070_-|penicillin-binding-protein	unknown	unknown	gnl|CDD|223815
NZ_CP010451.1|WP_038586445.1|3100248_3100572_-|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|225209
NZ_CP010451.1|WP_074508486.1|3085900_3087247_+|MFS-transporter	unknown	unknown	gnl|CDD|273327
NZ_CP010451.1|WP_040968054.1|3098794_3100105_-|ISL3-like-element-IS31831-family-transposase	unknown	unknown	gnl|CDD|225995
NZ_CP010451.1|WP_003855083.1|3096745_3097219_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP010451.1|WP_003855068.1|3090343_3090796_-|50S-ribosomal-protein-L9	unknown	unknown	gnl|CDD|234659
NZ_CP010451.1|WP_074508485.1|3087399_3087996_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP010451.1|WP_040968053.1|3098222_3098720_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010451.1|WP_003861174.1|3084960_3085335_-|thioredoxin	unknown	unknown	gnl|CDD|200072
NZ_CP010451.1|WP_040968048.1|3088203_3089736_-|replicative-DNA-helicase	unknown	unknown	gnl|CDD|180177
NZ_CP010451.1|WP_003855074.1|3091566_3091854_-|30S-ribosomal-protein-S6	unknown	unknown	gnl|CDD|179034
NZ_CP010451.1|WP_040968049.1|3092401_3093862_-|DUF2029-domain-containing-protein	unknown	unknown	gnl|CDD|227937
NZ_CP010451.1|WP_040968045.1|3081875_3083753_+|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319774
NZ_CP010451.1|WP_040968051.1|3096161_3096554_-|DUF5318-family-protein	unknown	unknown	gnl|CDD|379953
NZ_CP010451.1|WP_011015535.1|3080472_3080709_+|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl|CDD|225328
NZ_CP010451.1|WP_003861176.1|3085520_3085727_+|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl|CDD|225328
NZ_CP010451.1|WP_003861180.1|3087206_3087389_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010451.1|WP_074508484.1|3097246_3098191_+|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.85565e-14
NZ_CP010451.1|WP_040968050.1|3093907_3096070_-|penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	1.86347e-178
NZ_CP010451.1|WP_038586445.1|3100248_3100572_-|antibiotic-biosynthesis-monooxygenase	gnl|CDD|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	3.78442e-27
NZ_CP010451.1|WP_074508486.1|3085900_3087247_+|MFS-transporter	gnl|CDD|273327	TIGR00895, transport_protein, benzoate transport. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.08964e-63
NZ_CP010451.1|WP_003855083.1|3096745_3097219_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.61895e-16
NZ_CP010451.1|WP_003855068.1|3090343_3090796_-|50S-ribosomal-protein-L9	gnl|CDD|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	2.88421e-54
NZ_CP010451.1|WP_074508485.1|3087399_3087996_-|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.23864e-24
NZ_CP010451.1|WP_003861174.1|3084960_3085335_-|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	1.98121e-36
NZ_CP010451.1|WP_040968048.1|3088203_3089736_-|replicative-DNA-helicase	gnl|CDD|180177	PRK05636, PRK05636, replicative DNA helicase; Provisional.	0
NZ_CP010451.1|WP_003855074.1|3091566_3091854_-|30S-ribosomal-protein-S6	gnl|CDD|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	2.78025e-37
NZ_CP010451.1|WP_040968054.1|3098794_3100105_-|ISL3-like-element-IS31831-family-transposase	gnl|CDD|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.81073e-96
NZ_CP010451.1|WP_040968045.1|3081875_3083753_+|cadmium-translocating-P-type-ATPase	gnl|CDD|319774	cd02079, P-type_ATPase_HM, P-type heavy metal-transporting ATPase. Heavy metal-transporting ATPases (Type IB ATPases) transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. These ATPases include mammalian copper-transporting ATPases, ATP7A and ATP7B, Bacillus subtilis CadA which transports cadmium, zinc and cobalt out of the cell, Bacillus subtilis ZosA/PfeT which transports copper, and perhaps also zinc and ferrous iron, Archaeoglobus fulgidus CopA and CopB, Staphylococcus aureus plasmid pI258 CadA, a cadmium-efflux ATPase, and Escherichia coli ZntA which is selective for Pb(2+), Zn(2+), and Cd(2+). The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This family belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP010451.1|WP_040968051.1|3096161_3096554_-|DUF5318-family-protein	gnl|CDD|379953	pfam17249, DUF5318, Family of unknown function (DUF5318). This family of unknown function is mostly found in Actinobacteria.	3.04693e-35
NZ_CP010451.1|WP_011015535.1|3080472_3080709_+|heavy-metal-associated-domain-containing-protein	gnl|CDD|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	1.30916e-15
NZ_CP010451.1|WP_003861176.1|3085520_3085727_+|heavy-metal-associated-domain-containing-protein	gnl|CDD|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	9.07321e-13
NZ_CP010451.1|WP_040968049.1|3092401_3093862_-|DUF2029-domain-containing-protein	gnl|CDD|227937	COG5650, COG5650, Predicted integral membrane protein [Function unknown].	6.62122e-163

Protein sequences

>NZ_CP010451.1|WP_003855068.1|3090343_3090796_-|50S-ribosomal-protein-L9
MKLILTAAVENLGVAGDIVEVKNGYGRNLLLPRGLAIVATPGAEKQIEGIKRAQEAREIRDLDHAREVKAALEALEGVTIAVRTSESGKLFGSVKTDDIVDAVKAAGGPNLDKRAIVLPKNLVKTTGKYQVEAKLTDGIVSRVKFEVVAA
>NZ_CP010451.1|WP_040968048.1|3088203_3089736_-|replicative-DNA-helicase
MATDTHAASFDDDYVPPQEPSDSFADDAHVDVPAPAFEDFSPAQAFGQGTRGGDSQGFKKRGRKDETREYRDFRQPPYDNDAEMGVLGAMLLSPTTVIDILDILTPEDFYRPSHQLIFQAIIDLFSDNRDIDPVIVSGRLDRTNDLDRVGGGAYLHDLIQSVPTAANARYYAEIVSEKAVLRRLVDAGTRVVQLGYEGDEGAEIEAVIDRAQQEVFAVSQKNQSEDYAVLADILDETMAELEMLNDGGIATGIPTGFKDLDDLTNGLRGGQMIIVAARPGVGKSTIALDFMRSASIKNNMASVIFSLEMSKSEIVMRLLSAETEIRLADMRGGKMDETAWEKMVQKLDKVAQAPLFIDDSANLTMMEIRSKARKLKQKHDLKMIVVDYLQLMSSGKRVESRQQEVSEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADIVMLLYRPDSQDKDDERAGEADIILAKHRGGPIDTVQVAHQLHYSRFVDMARG
>NZ_CP010451.1|WP_074508485.1|3087399_3087996_-|PadR-family-transcriptional-regulator
MHFEELNNESCGSRGSGEFRGRPGRRHAQRHAEGHGHGHGHDRGHHHGRRPGRGRGGRAGRGDLRNVILVLLEAESMHGYQIITTISEQTEGNWTPSPGTIYPTLSMLEDEGLISVSHEMGRKMARLTEEGAQEVAKNKDAWGSILEAYRNPESREVRVFNIRSEFHKVREAAKAAPDDKAEQIIEILRRAADDIKRL
>NZ_CP010451.1|WP_003861180.1|3087206_3087389_-|hypothetical-protein
MQLREDIVVTRTQGATVIANLPRNLEDFRQAQKRTIVGQVKNWWKDLTNQRETYPSAQAA
>NZ_CP010451.1|WP_074508486.1|3085900_3087247_+|MFS-transporter
MPQRVIFSGMNLTRNDRLDRLPVTSKHKKILGGSGIGWALDAMDVGLISFVMAALATHWGLSPTETSLLGSIGFVGMAIGASLGGLLADKLGRRQVFALSLLVYGVATGASALSVSLAMLMALRFVVGLGLGAELPVASTLISEFSPRKVRGRMVVILEAFWALGWIMAAIVGTFVVAGSDNGWRWALALGCVPAIYAVYVRLGLPESVRFLEKKGRHDEAEAIVVSFEEAAAAEGKAADATTAVVHDNAAEGSVSIWSAALRKRTVALWIVWFCINLSYYGAFIWIPSLLVADGFTLVKSFQFTLIITLAQLPGYAVAAWLIEKWGRRSTLATFLVGSAISAALYGLANVEWQILVAGCLLSFFNLGAWGALYAIGPELYPTNVRGTGTGAAAGFGRIASIIAPLIVPPVIAFGGPIALFALFATAFAIAAIAAFTLPEQKGKSLAD
>NZ_CP010451.1|WP_003861176.1|3085520_3085727_+|heavy-metal-associated-domain-containing-protein
MSTKNYHVEGLTCANGVASVEDEIGIVAGTQGVDIDFETGRVTVTGEGFTDEEIIEAVANAGYKVSER
>NZ_CP010451.1|WP_003861174.1|3084960_3085335_-|thioredoxin
MATIDVTEETFESTVTGDGIVLVDAWASWCGPCRQFAPTYEKVSETHTDATFAKLDTEANQGLAAALQIQSIPTLMVFRDGIMVYREAGTMPAPALDDLVNQVKALDMDDVRRQVAEQQGSAEA
>NZ_CP010451.1|WP_040968045.1|3081875_3083753_+|cadmium-translocating-P-type-ATPase
MKTWKTWGIVAVSGLLIILSWLTPTGWLSDGFMIAAAVVAGWQIALSAYQALRIKMISIDLLVIVAAIGALFINNYWESAAVTFLFALGKALEKATMNRTRQALSDLVDAAPETATVLRDGEPETVEIWELAPGDVVLVKNGEQIPVDGRVLSGHGGVDEATITGESVPAEKAADSEVFAGTWLRSGVLRIEAIGIGSDSTLAKIIHRVEDAQDDKAKTQTFLEKFSKYYTPGVMIAALAVGLITLNVELALTLLVIACPGALVISIPVSIVAGIGRSAKDGVLIKGGEYLETSAKVDTVVVDKTGTLTNGRPELTNVDVLDPAYSDDEVLTLAARAETASEHPLAEAIIRGAENRGLTVAMVEKAEPVAGRGIRADVDGATVAVGSADLLDHTPDNTRILELNEQGRTAMYVGVNGKAVGIVAVADTIRDDAPAAIRSLHDKGIRVVMATGDAERVARNVAAELGVDEVRAELMPEDKLEIVKELQAQGRVVAMVGDGVNDTPALATADIGVAMGAAGSPAAIETADIALMADKLPRLPYALGLAQRTVRTMRVNIGIALLTVTILLAGVLLGGVTMSIGMLVHEASVLLVIAIAMLLLRPTLKEDKDKADVSTADAAKETLSA
>NZ_CP010451.1|WP_011015536.1|3080914_3081232_+|hypothetical-protein
MAEVTFASLHEKMNFLLKDHGVENFDESDLDLESVSSLHAKANALCAAHGGDPSRMANDTLAQLHPKLDFLMKGHGVDTDTARLDLSTLEAVDAKVNAVVNAHDH
>NZ_CP010451.1|WP_011015535.1|3080472_3080709_+|heavy-metal-associated-domain-containing-protein
MTAPATLKNTTLRSDEFTCPSCVAKIENKLNGLDGVENAEVKFSSGRILITHDPQKVSVRDLVTAVAEVGYTAKPSAI
>NZ_CP010451.1|WP_003855074.1|3091566_3091854_-|30S-ribosomal-protein-S6
MRQYELMIILDPSQDERTVAPSLDKFLEVVRKDKGDVVKVDVWGKRRLAYPIDKKEEGVYAVVDLKCESATVLELDRVLNLNDGVLRTKVLRLDK
>NZ_CP010451.1|WP_003861194.1|3092213_3092405_-|hypothetical-protein
MSTTVLLVTMVSVFVGFLCFGGAFASFMYKKSNKQIWTLFSIAIVLITVIPVTIAVFWATTPA
>NZ_CP010451.1|WP_040968049.1|3092401_3093862_-|DUF2029-domain-containing-protein
MDQKLDQQKVDRVSPGDSEPVARDFINAIGGRFGRFAQVGTQRFWTPLRVLIATSLVFLAMGFLTKANCIQGSRGTDGVVSLNWSGSRQYTSACYNDIVPLYGGRGIDAPGFPYAFSWQEGDLTRYMEYPVLGGIFQWICGIITRFLYPVVDVIPFHTLPESGLYFIVTALALAFFWVLVIRMMVELTGNRVWDTVLVAASPLVAVHAFTNWDTPAIAAVIGAMLAVKRGNPLVAGVLIGAGTAFKLWPLYLLGAYLVLAVKNKNLKPFITMAAAAAVTWLVVNVPVMIAYPKAWNEFLRLNRERGAEWTTIYQVIDRNLPINLNDPVLLNVLSFGLFGASCVAILILGLRVQRTPRVAELAFLIVAAFLLFNKVWSPQYSLWLVPLAVLAFPQWKVLFPWMVTDAMVWPILMWHMLGTDNKGLPHEMLDLIVISRDAFIVVMIVGVIRQMLGRRADPVMDAHAGRDLLAGPFGAGERRKALKEVS
>NZ_CP010451.1|WP_040968050.1|3093907_3096070_-|penicillin-binding-protein
MTNSKNPPAKKSSGKRRLKSDSNGHAVRNTIIGAIVAVILIPVMVFMGAYIMVDVPEPEELVSPQVSQIYASDGETELARIVPPEGNRQMVTIDQVPDTVKNAVVAAEDREFYTNPGFSITGYARAALGVITGDSSAGGGSTITQQYVKKAVVGDERSLIRKAKELVYSAKMANEWSKGEVLEAYLNTVYFGRNAYGVQAAAHAFFDKPVEELTAAEGAVLAASIQLPSQLDPWTNPVEAETRWNYVMDGLVEIGAISAEERAAATYPETTDPASNSAYTEATGANGLIKNQVMAELSELGITEDDVQTRGLQVTTTIDPKTQEGAVEAVQNQLDLLSENNRAAVVSIDPSNGAVRAYYGGEDATGWDFANAPIQTGSTFKIFGLAAALQQGIPLSQPYSSAPVTVGDAQIGNVGGSGCGSCSIEQALLRSYNTSFIRLQQDLENGSQDTADMAHALGIAESLPTIPETLTENGETPYEGIILGQYESRPFDMASAMATIANEGVWHRPHFVSKVETVSGEVLYEFEDGDGERRVSEKVALNLLKAMGPIAAYSNGNALADGQVSASKTGTTQLGDTGANKDAWMLGAAPQLATAVWVGTDDNTALYNTWGGSMYGSNSPATIWKQTMDNALENSPLETWDIAPALGYGNPPVPEYVWTPSPNIATNDPEVETEEAPVEDPNAVIDTPAVDPTAPAEETGNGQVEILPGLTIPGDLLGIG
>NZ_CP010451.1|WP_040968051.1|3096161_3096554_-|DUF5318-family-protein
MVGLRLHFLIVVQYQNEISHQLTRRQTLRQFRAGLVQKDTICDAEFILVTASKYHGRLADYPCPICGSEDLRVVLWVYGDEIGRAAGSARSEEEIEQLVKNGRQATVHTVEVCPTCKWNHLLKAETATAS
>NZ_CP010451.1|WP_003855083.1|3096745_3097219_+|MarR-family-transcriptional-regulator
MLAGMPNLNAEELAVRVRPALTKLYVLYFRRSVNSDLSGPQLTILSRLEENGPSRISRIAELEDIRMPTASNALHQLEQLNLVERIRDTKDRRGVQVQLTDHGREELERVNNERNAEMARLLEMLTPEQLERTEDLVDIITELAEVYGSWKETDSGS
>NZ_CP010451.1|WP_074508484.1|3097246_3098191_+|universal-stress-protein
MMKQPLRVLISCRPEENSGGKRSEQNDAVFEFAAWLARTSDINVRGITTFIRPWPSSSISKLGGKYHKWYKNLDSYYRSRTIKGLKEAGVEKSQWDDDVSVFVDGPSESTLLTHAAEEFEADLILLGSDATAPKGRFLASSTADALLHSSPVPLGLVPRGVKLSKKGVTRVNYAFTNESDDFEQGLRSSAELATNWNVPLRILAFSPTGITSAPTSRSLDISTELSSEWRELTLAMLDRARDGVLTDHPNLSVSSEIGSGWGWSGAIDALRWKKGDLLCMGSHRTDTLSRVFVGSETMEIIRNSPVPTIIYPGL
>NZ_CP010451.1|WP_040968053.1|3098222_3098720_+|hypothetical-protein
MPAKEDNFMNTQPEHPENDLVDEADFSNRPRIYSNDPDSLADAPDPALEHEKNKKSSRQALIYLFAVPLVTFVSAYVLAWVSRLQGGPICDAGEAVWICSRAAELWWPITTSVIAFGGMLGSAWILYDKYRNYLRWRPWMGVLWILIPFSMLWGTSVLTLSILGH
>NZ_CP010451.1|WP_040968054.1|3098794_3100105_-|ISL3-like-element-IS31831-family-transposase
MKSTGNIIADTICRTAELGLTITGASDAGDYTLIEADALDYTSTCPECSQPGVFRNHTHRMLIDLPIVGFPTKLFIRLPRYRCTNPTCKQKYFQAELSCADHGKKVTHRVTRWILQRLAIDRMSVHATAKALGLGWDLTCQLALDMCRELVYNDPHHLDGVYVIGVDEHKWSHNRAKHGDGFVTVIVDMTGHRYDSRCPARLLDVVPGRSADALRSWLGSRGEQFRNQIRIVSMDGFQGYATASKELIPSARRVMDPFHVVRLAGDKLTACRQRLQREKYQRRGLSQDPLYKNRKTLLTTHKWLSPRQQESLEQLWAYDKDYGVLKLAWLAYQAIIDCYQMGNKREAKKKMRTIIDQLRVLKGPNKELAQLGRSLFKRLGDVLAYFDVGVSNGPVEAINGRLEHLRGIALGFRNLNHYILRCLIHSGQLVHKINAL
>NZ_CP010451.1|WP_038586445.1|3100248_3100572_-|antibiotic-biosynthesis-monooxygenase
MSIVKINAISVPEGAGEELEKRFAARQNAVDSAPGFEGFQLLRPVSGEDRYFVVTQWANEDSYNAWRDAEKAKGGHGQGAHGSDKKPVASGASLLEFEVVLGSTGAK

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP010451_4	4.19|372375|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	372375-372407	33	NC_009343	Corynebacterium glutamicum R plasmid pCGR1, complete sequence	48485-48517	0	1.0
NZ_CP010451_5	5.13|376180|33|NZ_CP010451|CRISPRCasFinder,CRT	376180-376212	33	NC_042355	Corynebacterium phage phi674, complete genome	30272-30304	0	1.0
NZ_CP010451_5	5.13|376180|33|NZ_CP010451|CRISPRCasFinder,CRT	376180-376212	33	MG324354	Corynebacterium phage phi674	30272-30304	0	1.0
NZ_CP010451_5	5.13|376180|33|NZ_CP010451|CRISPRCasFinder,CRT	376180-376212	33	MG324353	Corynebacterium phage phi673	31097-31129	1	0.97
NZ_CP010451_5	5.13|376180|33|NZ_CP010451|CRISPRCasFinder,CRT	376180-376212	33	NC_042354	Corynebacterium phage phi673, complete genome	31097-31129	1	0.97
NZ_CP010451_3	3.15|370420|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	370420-370452	33	MN096367	Microbacterium phage Nucci, complete genome	29348-29380	2	0.939
NZ_CP010451_3	3.15|370420|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	370420-370452	33	MN284901	Microbacterium phage YuuY, complete genome	29984-30016	2	0.939
NZ_CP010451_4	4.18|372314|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	372314-372346	33	NC_009343	Corynebacterium glutamicum R plasmid pCGR1, complete sequence	19203-19235	2	0.939
NZ_CP010451_5	5.24|376851|33|NZ_CP010451|CRISPRCasFinder,CRT	376851-376883	33	NC_042355	Corynebacterium phage phi674, complete genome	6896-6928	2	0.939
NZ_CP010451_5	5.24|376851|33|NZ_CP010451|CRISPRCasFinder,CRT	376851-376883	33	MG324354	Corynebacterium phage phi674	6896-6928	2	0.939
NZ_CP010451_5	5.24|376851|33|NZ_CP010451|CRISPRCasFinder,CRT	376851-376883	33	MG324353	Corynebacterium phage phi673	6919-6951	2	0.939
NZ_CP010451_5	5.24|376851|33|NZ_CP010451|CRISPRCasFinder,CRT	376851-376883	33	NC_042354	Corynebacterium phage phi673, complete genome	6919-6951	2	0.939
NZ_CP010451_5	5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378622-378654	33	NC_009343	Corynebacterium glutamicum R plasmid pCGR1, complete sequence	9732-9764	2	0.939
NZ_CP010451_3	3.15|370420|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	370420-370452	33	NC_042118	Microbacterium phage Koji, complete genome	29486-29518	3	0.909
NZ_CP010451_5	5.19|376546|33|NZ_CP010451|CRISPRCasFinder,CRT	376546-376578	33	NC_009343	Corynebacterium glutamicum R plasmid pCGR1, complete sequence	24708-24740	3	0.909
NZ_CP010451_4	4.8|371702|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371702-371734	33	NZ_CP003998	Klebsiella pneumoniae subsp. pneumoniae Kp13 plasmid pKP13e, complete sequence	51992-52024	5	0.848
NZ_CP010451_3	3.5|369808|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369808-369840	33	NZ_CP022424	Vitreoscilla filiformis strain ATCC 15551 plasmid pVF1, complete sequence	46797-46829	6	0.818
NZ_CP010451_5	5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378622-378654	33	NC_015060	Granulicella tundricola MP5ACTX9 plasmid pACIX905, complete sequence	47278-47310	6	0.818
NZ_CP010451_8	8.1|3091012|27|NZ_CP010451|CRT	3091012-3091038	27	MN855869	Myoviridae sp. isolate 350, complete genome	6522-6548	6	0.778
NZ_CP010451_3	3.27|371153|33|NZ_CP010451|CRISPRCasFinder,CRT	371153-371185	33	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	511945-511977	7	0.788
NZ_CP010451_4	4.1|371275|33|NZ_CP010451|CRT	371275-371307	33	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	378280-378312	7	0.788
NZ_CP010451_4	4.1|371275|33|NZ_CP010451|CRT	371275-371307	33	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	50685-50717	7	0.788
NZ_CP010451_4	4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371580-371612	33	MH992208	Apis mellifera associated microvirus 51 isolate INH_SP_253, complete genome	746-778	7	0.788
NZ_CP010451_4	4.10|371824|34|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371824-371857	34	NZ_CP020041	Streptomyces sp. 3211 isolate 3 plasmid p3211-2, complete sequence	192030-192063	7	0.794
NZ_CP010451_5	5.33|377401|33|NZ_CP010451|CRISPRCasFinder,CRT	377401-377433	33	NC_014007	Sphingobium japonicum UT26S plasmid pCHQ1, complete sequence	58674-58706	7	0.788
NZ_CP010451_5	5.59|378988|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378988-379020	33	LR606148	Rhizobium sp. Q54 genome assembly, plasmid: 5	50199-50231	7	0.788
NZ_CP010451_5	5.59|378988|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378988-379020	33	LR606152	Rhizobium sp. Q54 genome assembly, plasmid: 9	28136-28168	7	0.788
NZ_CP010451_5	5.73|379843|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	379843-379875	33	NZ_CP049914	Vibrio sp. HDW18 plasmid p_unnamed1, complete sequence	214851-214883	7	0.788
NZ_CP010451_8	8.3|3091114|33|NZ_CP010451|CRT	3091114-3091146	33	MT498064	Microbacterium phage Pabst, complete genome	41428-41460	7	0.788
NZ_CP010451_3	3.18|370603|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	370603-370635	33	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	422159-422191	8	0.758
NZ_CP010451_3	3.21|370787|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	370787-370819	33	NZ_CP044544	Bradyrhizobium betae strain PL7HG1 plasmid pBbPL7HG1, complete sequence	12951-12983	8	0.758
NZ_CP010451_3	3.21|370787|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	370787-370819	33	NZ_CP044544	Bradyrhizobium betae strain PL7HG1 plasmid pBbPL7HG1, complete sequence	255822-255854	8	0.758
NZ_CP010451_3	3.21|370787|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	370787-370819	33	NZ_CP025114	Bradyrhizobium sp. SK17 strain CBNU plasmid unnamed, complete sequence	122717-122749	8	0.758
NZ_CP010451_4	4.12|371948|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371948-371980	33	NC_023285	Streptomyces sp. F8 plasmid pFRL5, complete sequence	234124-234156	8	0.758
NZ_CP010451_4	4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	372131-372163	33	KY365739	Streptomyces phage BabyGotBac, complete genome	40107-40139	8	0.758
NZ_CP010451_4	4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	372131-372163	33	KP876466	Streptomyces phage TP1604, complete genome	40110-40142	8	0.758
NZ_CP010451_5	5.33|377401|33|NZ_CP010451|CRISPRCasFinder,CRT	377401-377433	33	NZ_CP042332	Bosea sp. F3-2 plasmid pB32-1, complete sequence	166226-166258	8	0.758
NZ_CP010451_5	5.36|377584|33|NZ_CP010451|CRISPRCasFinder,CRT	377584-377616	33	NZ_CP015221	Rhodococcus sp. PBTS 2 plasmid unnamed1, complete sequence	11178-11210	8	0.758
NZ_CP010451_5	5.36|377584|33|NZ_CP010451|CRISPRCasFinder,CRT	377584-377616	33	NZ_CP015221	Rhodococcus sp. PBTS 2 plasmid unnamed1, complete sequence	136379-136411	8	0.758
NZ_CP010451_5	5.61|379110|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	379110-379142	33	NZ_CP032696	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525b, complete sequence	302975-303007	8	0.758
NZ_CP010451_3	3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369623-369656	34	MH590590	Microbacterium phage Schnapsidee, complete genome	27184-27217	9	0.735
NZ_CP010451_3	3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369623-369656	34	MG839030	Microbacterium phage Balsa, complete genome	27179-27212	9	0.735
NZ_CP010451_3	3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369623-369656	34	MH479922	Microbacterium phage Redfield, complete genome	27178-27211	9	0.735
NZ_CP010451_3	3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369623-369656	34	MG839024	Microbacterium phage Peppino, complete genome	27171-27204	9	0.735
NZ_CP010451_3	3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369623-369656	34	MG839025	Microbacterium phage Raccoon, complete genome	27146-27179	9	0.735
NZ_CP010451_3	3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369623-369656	34	MN062703	Microbacterium phage McGalleon, complete genome	28466-28499	9	0.735
NZ_CP010451_3	3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369623-369656	34	MH045555	Microbacterium phage BeeBee8, complete genome	27349-27382	9	0.735
NZ_CP010451_3	3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369685-369718	34	MH590590	Microbacterium phage Schnapsidee, complete genome	27184-27217	9	0.735
NZ_CP010451_3	3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369685-369718	34	MG839030	Microbacterium phage Balsa, complete genome	27179-27212	9	0.735
NZ_CP010451_3	3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369685-369718	34	MH479922	Microbacterium phage Redfield, complete genome	27178-27211	9	0.735
NZ_CP010451_3	3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369685-369718	34	MG839024	Microbacterium phage Peppino, complete genome	27171-27204	9	0.735
NZ_CP010451_3	3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369685-369718	34	MG839025	Microbacterium phage Raccoon, complete genome	27146-27179	9	0.735
NZ_CP010451_3	3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369685-369718	34	MN062703	Microbacterium phage McGalleon, complete genome	28466-28499	9	0.735
NZ_CP010451_3	3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369685-369718	34	MH045555	Microbacterium phage BeeBee8, complete genome	27349-27382	9	0.735
NZ_CP010451_3	3.5|369808|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369808-369840	33	NZ_LR594663	Variovorax sp. RA8 plasmid 2	123519-123551	9	0.727
NZ_CP010451_3	3.19|370664|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	370664-370696	33	LR721752	Aliivibrio wodanis 06/09/160 plasmid 1 complete sequence	45258-45290	9	0.727
NZ_CP010451_4	4.5|371519|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371519-371551	33	MH450115	Arthrobacter phage Breylor17, complete genome	27875-27907	9	0.727
NZ_CP010451_4	4.5|371519|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371519-371551	33	MH479926	Arthrobacter phage Synepsis, complete genome	27333-27365	9	0.727
NZ_CP010451_4	4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371580-371612	33	NZ_CP021459	Lactobacillus brevis strain ZLB004 plasmid p3, complete sequence	5420-5452	9	0.727
NZ_CP010451_4	4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371580-371612	33	NZ_CP016799	Lactobacillus brevis strain TMW 1.2112 plasmid pl12112-2, complete sequence	7979-8011	9	0.727
NZ_CP010451_4	4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371580-371612	33	NZ_CP019736	Lactobacillus brevis strain TMW 1.2108 plasmid pl12108-2, complete sequence	49546-49578	9	0.727
NZ_CP010451_4	4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371580-371612	33	NZ_CP019745	Lactobacillus brevis strain TMW 1.2111 plasmid pl12111-2, complete sequence	689-721	9	0.727
NZ_CP010451_4	4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371580-371612	33	NZ_CP021480	Lactobacillus brevis strain SRCM101174 plasmid pLB1174-2, complete sequence	2646-2678	9	0.727
NZ_CP010451_4	4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371580-371612	33	NZ_CP021480	Lactobacillus brevis strain SRCM101174 plasmid pLB1174-2, complete sequence	34842-34874	9	0.727
NZ_CP010451_4	4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	371580-371612	33	NZ_CP019753	Lactobacillus brevis strain TMW 1.2113 plasmid pl12113-3, complete sequence	3597-3629	9	0.727
NZ_CP010451_4	4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	372131-372163	33	NZ_CP015040	Rhodovulum sp. P5 plasmid pRGUI01, complete sequence	98775-98807	9	0.727
NZ_CP010451_5	5.5|375692|33|NZ_CP010451|CRISPRCasFinder,CRT	375692-375724	33	NZ_CP044405	Escherichia coli strain NMBU-W10C18 plasmid pNMBU-W10C18_03, complete sequence	1461-1493	9	0.727
NZ_CP010451_5	5.5|375692|33|NZ_CP010451|CRISPRCasFinder,CRT	375692-375724	33	NZ_CP047611	Escherichia coli strain NMBU_ W06E18 plasmid pNMBU_W06E18_Str1_2, complete sequence	26564-26596	9	0.727
NZ_CP010451_5	5.7|375814|33|NZ_CP010451|CRISPRCasFinder,CRT	375814-375846	33	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	36653-36685	9	0.727
NZ_CP010451_5	5.7|375814|33|NZ_CP010451|CRISPRCasFinder,CRT	375814-375846	33	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	62811-62843	9	0.727
NZ_CP010451_5	5.44|378072|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378072-378104	33	KX889311	Pseudomonas aeruginosa plasmid pJB12, complete sequence	2109-2141	9	0.727
NZ_CP010451_5	5.67|379476|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	379476-379508	33	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1103454-1103486	9	0.727
NZ_CP010451_5	5.67|379476|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	379476-379508	33	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	321868-321900	9	0.727
NZ_CP010451_5	5.67|379476|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	379476-379508	33	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1028919-1028951	9	0.727
NZ_CP010451_5	5.75|379965|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	379965-379997	33	MK433276	Streptomyces phage Asten, complete genome	15090-15122	9	0.727
NZ_CP010451_5	5.75|379965|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	379965-379997	33	MN284899	Streptomyces phage Whatever, complete genome	15101-15133	9	0.727
NZ_CP010451_5	5.75|379965|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	379965-379997	33	MG757163	Streptomyces phage OzzyJ, complete genome	15091-15123	9	0.727
NZ_CP010451_8	8.3|3091114|33|NZ_CP010451|CRT	3091114-3091146	33	NC_008043	Ruegeria sp. TM1040 megaplasmid, complete sequence	126742-126774	9	0.727
NZ_CP010451_3	3.5|369808|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	369808-369840	33	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	261219-261251	10	0.697
NZ_CP010451_3	3.9|370053|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	370053-370086	34	KT588074	Acinetobacter phage Ab105-1phi, complete genome	21275-21308	10	0.706
NZ_CP010451_3	3.9|370053|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT	370053-370086	34	MK340941	Acinetobacter phage AbTJ, complete genome	21629-21662	10	0.706
NZ_CP010451_4	4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	372131-372163	33	NC_021086	Cutibacterium acnes HL096PA1 plasmid unnamed, complete sequence	9430-9462	10	0.697
NZ_CP010451_4	4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	372131-372163	33	NZ_CP012356	Cutibacterium acnes strain PA_15_1_R1 plasmid unnamed, complete sequence	9284-9316	10	0.697
NZ_CP010451_4	4.17|372253|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder	372253-372285	33	MK448854	Streptococcus phage Javan146, complete genome	51-83	10	0.697
NZ_CP010451_5	5.42|377950|33|NZ_CP010451|CRISPRCasFinder,CRT	377950-377982	33	NC_019339	Arthrobacter sp. J3-49 plasmid pJ349-116, complete sequence	51682-51714	10	0.697
NZ_CP010451_5	5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378622-378654	33	NZ_CP013419	Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence	39454-39486	10	0.697
NZ_CP010451_5	5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378622-378654	33	NZ_CP013419	Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence	137231-137263	10	0.697
NZ_CP010451_5	5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378622-378654	33	NZ_CP013419	Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence	204936-204968	10	0.697
NZ_CP010451_5	5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378622-378654	33	NZ_CP013419	Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence	341003-341035	10	0.697
NZ_CP010451_5	5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378622-378654	33	NZ_CP013419	Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence	11589-11621	10	0.697
NZ_CP010451_5	5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378622-378654	33	NZ_CP010016	Burkholderia thailandensis 34 plasmid unnamed, complete sequence	58215-58247	10	0.697
NZ_CP010451_5	5.54|378683|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378683-378715	33	NZ_CP010871	Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6002, complete sequence	131090-131122	10	0.697
NZ_CP010451_5	5.54|378683|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR	378683-378715	33	NZ_CP010870	Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6001, complete sequence	74830-74862	10	0.697
NZ_CP010451_8	8.3|3091114|33|NZ_CP010451|CRT	3091114-3091146	33	NZ_CP028345	Vibrio parahaemolyticus isolate R13 plasmid pVpR13_55Kb, complete sequence	5601-5633	10	0.697
NZ_CP010451_8	8.3|3091114|33|NZ_CP010451|CRT	3091114-3091146	33	NZ_CP028144	Vibrio parahaemolyticus strain R14 plasmid pVpR14_56Kb, complete sequence	39135-39167	10	0.697

1. spacer 4.19|372375|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NC_009343 (Corynebacterium glutamicum R plasmid pCGR1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagaacattcgactccgcagccaacacacg	CRISPR spacer
caaaagaacattcgactccgcagccaacacacg	Protospacer
*********************************

2. spacer 5.13|376180|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NC_042355 (Corynebacterium phage phi674, complete genome) position: , mismatch: 0, identity: 1.0

tgaggccatatttcagagatgttgtcttagatg	CRISPR spacer
tgaggccatatttcagagatgttgtcttagatg	Protospacer
*********************************

3. spacer 5.13|376180|33|NZ_CP010451|CRISPRCasFinder,CRT matches to MG324354 (Corynebacterium phage phi674) position: , mismatch: 0, identity: 1.0

tgaggccatatttcagagatgttgtcttagatg	CRISPR spacer
tgaggccatatttcagagatgttgtcttagatg	Protospacer
*********************************

4. spacer 5.13|376180|33|NZ_CP010451|CRISPRCasFinder,CRT matches to MG324353 (Corynebacterium phage phi673) position: , mismatch: 1, identity: 0.97

tgaggccatatttcagagatgttgtcttagatg	CRISPR spacer
tgagaccatatttcagagatgttgtcttagatg	Protospacer
****.****************************

5. spacer 5.13|376180|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NC_042354 (Corynebacterium phage phi673, complete genome) position: , mismatch: 1, identity: 0.97

tgaggccatatttcagagatgttgtcttagatg	CRISPR spacer
tgagaccatatttcagagatgttgtcttagatg	Protospacer
****.****************************

6. spacer 3.15|370420|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MN096367 (Microbacterium phage Nucci, complete genome) position: , mismatch: 2, identity: 0.939

atgcggtcgctggcttgcttaaacgtgacatag	CRISPR spacer
atgcggtcgctggcttgcttgaacgtgacgtag	Protospacer
********************.********.***

7. spacer 3.15|370420|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MN284901 (Microbacterium phage YuuY, complete genome) position: , mismatch: 2, identity: 0.939

atgcggtcgctggcttgcttaaacgtgacatag	CRISPR spacer
atgcggtcgctggcttgcttgaacgtgacgtag	Protospacer
********************.********.***

8. spacer 4.18|372314|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NC_009343 (Corynebacterium glutamicum R plasmid pCGR1, complete sequence) position: , mismatch: 2, identity: 0.939

cgctttgcgatctggattcgctcttcctttgcc	CRISPR spacer
cgctttgcgatctggattcgctcttcttttgct	Protospacer
**************************.*****.

9. spacer 5.24|376851|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NC_042355 (Corynebacterium phage phi674, complete genome) position: , mismatch: 2, identity: 0.939

ccctccactgagagcgtagatccagtggagagc	CRISPR spacer
ccctccactgagagagtagacccagtggagagc	Protospacer
************** *****.************

10. spacer 5.24|376851|33|NZ_CP010451|CRISPRCasFinder,CRT matches to MG324354 (Corynebacterium phage phi674) position: , mismatch: 2, identity: 0.939

ccctccactgagagcgtagatccagtggagagc	CRISPR spacer
ccctccactgagagagtagacccagtggagagc	Protospacer
************** *****.************

11. spacer 5.24|376851|33|NZ_CP010451|CRISPRCasFinder,CRT matches to MG324353 (Corynebacterium phage phi673) position: , mismatch: 2, identity: 0.939

ccctccactgagagcgtagatccagtggagagc	CRISPR spacer
ccctccactgagagagtagacccagtggagagc	Protospacer
************** *****.************

12. spacer 5.24|376851|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NC_042354 (Corynebacterium phage phi673, complete genome) position: , mismatch: 2, identity: 0.939

ccctccactgagagcgtagatccagtggagagc	CRISPR spacer
ccctccactgagagagtagacccagtggagagc	Protospacer
************** *****.************

13. spacer 5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NC_009343 (Corynebacterium glutamicum R plasmid pCGR1, complete sequence) position: , mismatch: 2, identity: 0.939

ggctcggtgagcttcacgcgatcctgtttgcgg	CRISPR spacer
ggttcggtgagtttcacgcgatcctgtttgcgg	Protospacer
**.********.*********************

14. spacer 3.15|370420|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to NC_042118 (Microbacterium phage Koji, complete genome) position: , mismatch: 3, identity: 0.909

atgcggtcgctggcttgcttaaacgtgacatag	CRISPR spacer
atgcggtcgctggcctgcttgaacgtgacatac	Protospacer
**************.*****.*********** 

15. spacer 5.19|376546|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NC_009343 (Corynebacterium glutamicum R plasmid pCGR1, complete sequence) position: , mismatch: 3, identity: 0.909

actcaggccaccactcgggcactgaatcggcgg	CRISPR spacer
agtcaggccaccactcgggcactgaatcgggag	Protospacer
* **************************** .*

16. spacer 4.8|371702|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP003998 (Klebsiella pneumoniae subsp. pneumoniae Kp13 plasmid pKP13e, complete sequence) position: , mismatch: 5, identity: 0.848

attgct--catatgggcgggcagactgctgcgcag	CRISPR spacer
--cgctggcatatgggcgggcagactgctgtgctg	Protospacer
  .***  **********************.** *

17. spacer 3.5|369808|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022424 (Vitreoscilla filiformis strain ATCC 15551 plasmid pVF1, complete sequence) position: , mismatch: 6, identity: 0.818

gccacatgcgccaccacctcagccg-gggcacca	CRISPR spacer
gccacatgcgccaacgcctcagccaccgtcacc-	Protospacer
************* *.********.  * **** 

18. spacer 5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NC_015060 (Granulicella tundricola MP5ACTX9 plasmid pACIX905, complete sequence) position: , mismatch: 6, identity: 0.818

ggctcggtgagcttcacgcgatcct-gtttgcgg	CRISPR spacer
ggctcggtgagcttgtcgcgatcctcgcgtgct-	Protospacer
**************  ********* *. ***  

19. spacer 8.1|3091012|27|NZ_CP010451|CRT matches to MN855869 (Myoviridae sp. isolate 350, complete genome) position: , mismatch: 6, identity: 0.778

tccgccctggttgctttgctgctggtt	CRISPR spacer
accgccctgctttctttgctgctgcgg	Protospacer
 ******** ** ***********   

20. spacer 3.27|371153|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 7, identity: 0.788

cgccttgt-cgacggccacggtaatgggggagac	CRISPR spacer
-gccgaatacgacggtgacggtaatgggggagaa	Protospacer
 ***  .* ******. **************** 

21. spacer 4.1|371275|33|NZ_CP010451|CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 7, identity: 0.788

gaatcggcgatacagagcagcgccacgctcgtg	CRISPR spacer
gcctcggcgctaaagagcagcgccacgcgctcg	Protospacer
*  ****** ** *************** * .*

22. spacer 4.1|371275|33|NZ_CP010451|CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 7, identity: 0.788

gaatcggcgatacagagcagcgccacgctcgtg	CRISPR spacer
gcctcggcgctaaagagcagcgccacgcgctcg	Protospacer
*  ****** ** *************** * .*

23. spacer 4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to MH992208 (Apis mellifera associated microvirus 51 isolate INH_SP_253, complete genome) position: , mismatch: 7, identity: 0.788

tggggcttgatgtggaagaaattaaggctgagc	CRISPR spacer
ttggtttagatgaggaaaaaattaaggctgaga	Protospacer
* ** .* **** ****.************** 

24. spacer 4.10|371824|34|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP020041 (Streptomyces sp. 3211 isolate 3 plasmid p3211-2, complete sequence) position: , mismatch: 7, identity: 0.794

-agcaggcgtccgacttgcacgcgattacgatcct	CRISPR spacer
cagca-ccagccgacttgcaggcgattccgatcca	Protospacer
 ****  *. ********** ****** ****** 

25. spacer 5.33|377401|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NC_014007 (Sphingobium japonicum UT26S plasmid pCHQ1, complete sequence) position: , mismatch: 7, identity: 0.788

-ccgactttaagcgcaacgaagccctcaacgacg	CRISPR spacer
agcggcatc-agcgcaaggaagcgctcaacgacg	Protospacer
  **.* *. ******* ***** **********

26. spacer 5.59|378988|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to LR606148 (Rhizobium sp. Q54 genome assembly, plasmid: 5) position: , mismatch: 7, identity: 0.788

ctgcagtcaactcctctgcgaacgccgctgccc	CRISPR spacer
gggcaccgaactcctctgcgaacgccgcagcct	Protospacer
  *** . ******************** ***.

27. spacer 5.59|378988|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to LR606152 (Rhizobium sp. Q54 genome assembly, plasmid: 9) position: , mismatch: 7, identity: 0.788

ctgcagtcaactcctctgcgaacgccgctgccc	CRISPR spacer
gggcaccgaactcctctgcgaacgccgcagcct	Protospacer
  *** . ******************** ***.

28. spacer 5.73|379843|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049914 (Vibrio sp. HDW18 plasmid p_unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

gttcatggttttgcgattgattccatgatcacc	CRISPR spacer
gattttggttttgcgattgattggatgatcaaa	Protospacer
* *. *****************  *******  

29. spacer 8.3|3091114|33|NZ_CP010451|CRT matches to MT498064 (Microbacterium phage Pabst, complete genome) position: , mismatch: 7, identity: 0.788

gccaccaccttggttgccgccaccgtagtttcc	CRISPR spacer
gccaccaccggggttgccgccacccgagccacc	Protospacer
*********  *************  **.. **

30. spacer 3.18|370603|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

atgatcttacagtgcgagcgacgctcggccccg	CRISPR spacer
ggcacattgcagtgcgagccacgctcggcccgg	Protospacer
.  *. **.********** *********** *

31. spacer 3.21|370787|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044544 (Bradyrhizobium betae strain PL7HG1 plasmid pBbPL7HG1, complete sequence) position: , mismatch: 8, identity: 0.758

tgattggttcgatggccgattcattgactgtgg	CRISPR spacer
ggatcatttcgatggccgattccttgacggtct	Protospacer
 ***.. *************** ***** **  

32. spacer 3.21|370787|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044544 (Bradyrhizobium betae strain PL7HG1 plasmid pBbPL7HG1, complete sequence) position: , mismatch: 8, identity: 0.758

tgattggttcgatggccgattcattgactgtgg	CRISPR spacer
ggatcatttcgatggccgattccttgacggtct	Protospacer
 ***.. *************** ***** **  

33. spacer 3.21|370787|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025114 (Bradyrhizobium sp. SK17 strain CBNU plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

tgattggttcgatggccgattcattgactgtgg	CRISPR spacer
ggatcatttcgatggccgattccttgacggtct	Protospacer
 ***.. *************** ***** **  

34. spacer 4.12|371948|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NC_023285 (Streptomyces sp. F8 plasmid pFRL5, complete sequence) position: , mismatch: 8, identity: 0.758

gaaccttggttgcgtccgcttcgccagaagaac	CRISPR spacer
cgaaccagcttgcgtacgcttcggcagaagaac	Protospacer
 .* *. * ****** ******* *********

35. spacer 4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to KY365739 (Streptomyces phage BabyGotBac, complete genome) position: , mismatch: 8, identity: 0.758

caacgaccatcgcgaagctgaacggattcatcc	CRISPR spacer
cgaagctgttcgggaagctgaacggcttcatcc	Protospacer
*.* * .  *** ************ *******

36. spacer 4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to KP876466 (Streptomyces phage TP1604, complete genome) position: , mismatch: 8, identity: 0.758

caacgaccatcgcgaagctgaacggattcatcc	CRISPR spacer
cgaagctgttcgggaagctgaacggcttcatcc	Protospacer
*.* * .  *** ************ *******

37. spacer 5.33|377401|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NZ_CP042332 (Bosea sp. F3-2 plasmid pB32-1, complete sequence) position: , mismatch: 8, identity: 0.758

---ccgactttaagcgcaacgaagccctcaacgacg	CRISPR spacer
agctcggc---gagcgcaacgaagccctcgacggcg	Protospacer
   .**.*   .*****************.***.**

38. spacer 5.36|377584|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NZ_CP015221 (Rhodococcus sp. PBTS 2 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

tgaatccttaccacgaggccatgcagcaatcgg	CRISPR spacer
tgcgcggttaccacgaagccatgcaggaatcag	Protospacer
** ..  *********.********* ****.*

39. spacer 5.36|377584|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NZ_CP015221 (Rhodococcus sp. PBTS 2 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

tgaatccttaccacgaggccatgcagcaatcgg	CRISPR spacer
tgcgcggttaccacgaagccatgcaggaatcag	Protospacer
** ..  *********.********* ****.*

40. spacer 5.61|379110|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032696 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525b, complete sequence) position: , mismatch: 8, identity: 0.758

cgagtaatgatcgcgttgattaggactggatag	CRISPR spacer
caaacttggatcgcattgactaggactggatag	Protospacer
*.*..   ******.****.*************

41. spacer 3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MH590590 (Microbacterium phage Schnapsidee, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

42. spacer 3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MG839030 (Microbacterium phage Balsa, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

43. spacer 3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MH479922 (Microbacterium phage Redfield, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

44. spacer 3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MG839024 (Microbacterium phage Peppino, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

45. spacer 3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MG839025 (Microbacterium phage Raccoon, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

46. spacer 3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MN062703 (Microbacterium phage McGalleon, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gcgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

47. spacer 3.2|369623|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MH045555 (Microbacterium phage BeeBee8, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

48. spacer 3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MH590590 (Microbacterium phage Schnapsidee, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

49. spacer 3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MG839030 (Microbacterium phage Balsa, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

50. spacer 3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MH479922 (Microbacterium phage Redfield, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

51. spacer 3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MG839024 (Microbacterium phage Peppino, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

52. spacer 3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MG839025 (Microbacterium phage Raccoon, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

53. spacer 3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MN062703 (Microbacterium phage McGalleon, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gcgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

54. spacer 3.3|369685|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MH045555 (Microbacterium phage BeeBee8, complete genome) position: , mismatch: 9, identity: 0.735

gggaagcgcttgccgagtactaaaggcttgagag	CRISPR spacer
gtgaagcgcttgccgagttctaagggcaaggcca	Protospacer
* **************** ****.***  *.  .

55. spacer 3.5|369808|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594663 (Variovorax sp. RA8 plasmid 2) position: , mismatch: 9, identity: 0.727

gccacatgcgccaccacctcagccggggcacca	CRISPR spacer
cggatgtgcgccaccagctcggccggggcatcg	Protospacer
   *..********** ***.*********.*.

56. spacer 3.19|370664|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to LR721752 (Aliivibrio wodanis 06/09/160 plasmid 1 complete sequence) position: , mismatch: 9, identity: 0.727

tgttccaagctgcgaaagcatggtttccagtag	CRISPR spacer
gttttcaggctgcgaaagcatggtttttatagg	Protospacer
  **.**.******************..*  .*

57. spacer 4.5|371519|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to MH450115 (Arthrobacter phage Breylor17, complete genome) position: , mismatch: 9, identity: 0.727

gactgtcctggctggtgttccggaggctactac	CRISPR spacer
tattcagacggctggtgttccggaagctcctac	Protospacer
 *.*    .***************.*** ****

58. spacer 4.5|371519|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to MH479926 (Arthrobacter phage Synepsis, complete genome) position: , mismatch: 9, identity: 0.727

gactgtcctggctggtgttccggaggctactac	CRISPR spacer
tattcagacggctggtgttccggaagctcctac	Protospacer
 *.*    .***************.*** ****

59. spacer 4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021459 (Lactobacillus brevis strain ZLB004 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.727

tggggcttgatgtggaagaaattaaggctgagc	CRISPR spacer
ctaaggctgatcaggaagaaattaaggctgatc	Protospacer
. ..* .****  ****************** *

60. spacer 4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP016799 (Lactobacillus brevis strain TMW 1.2112 plasmid pl12112-2, complete sequence) position: , mismatch: 9, identity: 0.727

tggggcttgatgtggaagaaattaaggctgagc	CRISPR spacer
ctaaggctgatcaggaagaaattaaggctgatc	Protospacer
. ..* .****  ****************** *

61. spacer 4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP019736 (Lactobacillus brevis strain TMW 1.2108 plasmid pl12108-2, complete sequence) position: , mismatch: 9, identity: 0.727

tggggcttgatgtggaagaaattaaggctgagc	CRISPR spacer
ctaaggctgatcaggaagaaattaaggctgatc	Protospacer
. ..* .****  ****************** *

62. spacer 4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP019745 (Lactobacillus brevis strain TMW 1.2111 plasmid pl12111-2, complete sequence) position: , mismatch: 9, identity: 0.727

tggggcttgatgtggaagaaattaaggctgagc	CRISPR spacer
ctaaggctgatcaggaagaaattaaggctgatc	Protospacer
. ..* .****  ****************** *

63. spacer 4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021480 (Lactobacillus brevis strain SRCM101174 plasmid pLB1174-2, complete sequence) position: , mismatch: 9, identity: 0.727

tggggcttgatgtggaagaaattaaggctgagc	CRISPR spacer
ctaaggctgatcaggaagaaattaaggctgatc	Protospacer
. ..* .****  ****************** *

64. spacer 4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021480 (Lactobacillus brevis strain SRCM101174 plasmid pLB1174-2, complete sequence) position: , mismatch: 9, identity: 0.727

tggggcttgatgtggaagaaattaaggctgagc	CRISPR spacer
ctaaggctgatcaggaagaaattaaggctgatc	Protospacer
. ..* .****  ****************** *

65. spacer 4.6|371580|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP019753 (Lactobacillus brevis strain TMW 1.2113 plasmid pl12113-3, complete sequence) position: , mismatch: 9, identity: 0.727

tggggcttgatgtggaagaaattaaggctgagc	CRISPR spacer
ctaaggctgatcaggaagaaattaaggctgatc	Protospacer
. ..* .****  ****************** *

66. spacer 4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP015040 (Rhodovulum sp. P5 plasmid pRGUI01, complete sequence) position: , mismatch: 9, identity: 0.727

caacgaccatcgcgaagctgaacggattcatcc	CRISPR spacer
cgccgacaatcgcgaagctgagcggatcgccct	Protospacer
*. **** *************.*****.  .*.

67. spacer 5.5|375692|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NZ_CP044405 (Escherichia coli strain NMBU-W10C18 plasmid pNMBU-W10C18_03, complete sequence) position: , mismatch: 9, identity: 0.727

tggttgtatttttgctgcgcctccaagaaagcc	CRISPR spacer
ggattgtatttttgctgcgcatccgagcgacta	Protospacer
 *.***************** ***.** .* . 

68. spacer 5.5|375692|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NZ_CP047611 (Escherichia coli strain NMBU_ W06E18 plasmid pNMBU_W06E18_Str1_2, complete sequence) position: , mismatch: 9, identity: 0.727

tggttgtatttttgctgcgcctccaagaaagcc	CRISPR spacer
ggattgtatttttgctgcgcatccgagcgacta	Protospacer
 *.***************** ***.** .* . 

69. spacer 5.7|375814|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 9, identity: 0.727

gcggtaacccatgagacgctcaggggcatccgg	CRISPR spacer
agccttgcccatgagtcgctcacgggcatcccg	Protospacer
.   * .******** ****** ******** *

70. spacer 5.7|375814|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 9, identity: 0.727

gcggtaacccatgagacgctcaggggcatccgg	CRISPR spacer
agccttgcccatgagtcgctcacgggcatcccg	Protospacer
.   * .******** ****** ******** *

71. spacer 5.44|378072|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to KX889311 (Pseudomonas aeruginosa plasmid pJB12, complete sequence) position: , mismatch: 9, identity: 0.727

----gtgtcacccgcctcaagaacgatggtgccggac	CRISPR spacer
tccggt----tccgcctcaagaacggtcgtgccggcg	Protospacer
    **    .**************.* *******  

72. spacer 5.67|379476|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.727

tatgcggtggcgcaccaggcacgcacaggggct	CRISPR spacer
gagcgggtggcgctccaggcgcgcacaggcgtg	Protospacer
 *   ******** ******.******** *. 

73. spacer 5.67|379476|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.727

tatgcggtggcgcaccaggcacgcacaggggct	CRISPR spacer
gagcgggtggcgctccaggcgcgcacaggcgtg	Protospacer
 *   ******** ******.******** *. 

74. spacer 5.67|379476|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 9, identity: 0.727

tatgcggtggcgcaccaggcacgcacaggggct	CRISPR spacer
gagcgggtggcgctccaggcgcgcacaggcgtg	Protospacer
 *   ******** ******.******** *. 

75. spacer 5.75|379965|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to MK433276 (Streptomyces phage Asten, complete genome) position: , mismatch: 9, identity: 0.727

tggagcgtgacagcaccatcacccacaccgtca	CRISPR spacer
cgccggtagacagcaccatcacccgcaccctcg	Protospacer
.*  *   ****************.**** **.

76. spacer 5.75|379965|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to MN284899 (Streptomyces phage Whatever, complete genome) position: , mismatch: 9, identity: 0.727

tggagcgtgacagcaccatcacccacaccgtca	CRISPR spacer
cgccggtagacagcaccatcacccgcaccctcg	Protospacer
.*  *   ****************.**** **.

77. spacer 5.75|379965|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to MG757163 (Streptomyces phage OzzyJ, complete genome) position: , mismatch: 9, identity: 0.727

tggagcgtgacagcaccatcacccacaccgtca	CRISPR spacer
cgccggtagacagcaccatcacccgcaccctcg	Protospacer
.*  *   ****************.**** **.

78. spacer 8.3|3091114|33|NZ_CP010451|CRT matches to NC_008043 (Ruegeria sp. TM1040 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.727

gccaccaccttggttgccgccaccgtagtttcc	CRISPR spacer
gccaccaccttgcctgccgccaccttgccccgc	Protospacer
************ .********** *. ... *

79. spacer 3.5|369808|33|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 10, identity: 0.697

gccacatgcgccaccacctcagccggggcacca	CRISPR spacer
cggacatgcgccaccgcctcggccgggaaattg	Protospacer
   ************.****.******. *...

80. spacer 3.9|370053|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to KT588074 (Acinetobacter phage Ab105-1phi, complete genome) position: , mismatch: 10, identity: 0.706

cagcgaccaacgttagtaaaacctgggcacagct	CRISPR spacer
gtgcgaccaacgttaataaaaactggaaactagc	Protospacer
  *************.***** ****. ** . .

81. spacer 3.9|370053|34|NZ_CP010451|PILER-CR,CRISPRCasFinder,CRT matches to MK340941 (Acinetobacter phage AbTJ, complete genome) position: , mismatch: 10, identity: 0.706

cagcgaccaacgttagtaaaacctgggcacagct	CRISPR spacer
gtgcgaccaacgttaataaaaactggaaactagc	Protospacer
  *************.***** ****. ** . .

82. spacer 4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NC_021086 (Cutibacterium acnes HL096PA1 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

caacgaccatcgcgaagctgaacggattcatcc	CRISPR spacer
ccacgaccatcgccaagctgaatggagagcgag	Protospacer
* *********** ********.***       

83. spacer 4.15|372131|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP012356 (Cutibacterium acnes strain PA_15_1_R1 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

caacgaccatcgcgaagctgaacggattcatcc	CRISPR spacer
ccacgaccatcgccaagctgaatggagagcgag	Protospacer
* *********** ********.***       

84. spacer 4.17|372253|33|NZ_CP010451|CRT,PILER-CR,CRISPRCasFinder matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 10, identity: 0.697

caaccttgagtttatctacctgatcggcactgg	CRISPR spacer
tttctttgagtttatctagctgatgggcataca	Protospacer
.  *.************* ***** ****.  .

85. spacer 5.42|377950|33|NZ_CP010451|CRISPRCasFinder,CRT matches to NC_019339 (Arthrobacter sp. J3-49 plasmid pJ349-116, complete sequence) position: , mismatch: 10, identity: 0.697

ggcatggcacaagaggatcgacaggaagccgca	CRISPR spacer
gttcgcaaacaacaggttcgacaggaagccgcg	Protospacer
* .   . **** *** ***************.

86. spacer 5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013419 (Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence) position: , mismatch: 10, identity: 0.697

ggctcggtgagcttcacgcgatcctgtttgcgg	CRISPR spacer
tacagcagaagcttcacgcgatcgcgtttgcgg	Protospacer
 .*   . .************** .********

87. spacer 5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013419 (Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence) position: , mismatch: 10, identity: 0.697

ggctcggtgagcttcacgcgatcctgtttgcgg	CRISPR spacer
tacagcagaagcttcacgcgatcgcgtttgcgg	Protospacer
 .*   . .************** .********

88. spacer 5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013419 (Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence) position: , mismatch: 10, identity: 0.697

ggctcggtgagcttcacgcgatcctgtttgcgg	CRISPR spacer
tacagcagaagcttcacgcgatcgcgtttgcgg	Protospacer
 .*   . .************** .********

89. spacer 5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013419 (Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence) position: , mismatch: 10, identity: 0.697

ggctcggtgagcttcacgcgatcctgtttgcgg	CRISPR spacer
tacagcagaagcttcacgcgatcgcgtttgcgg	Protospacer
 .*   . .************** .********

90. spacer 5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013419 (Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence) position: , mismatch: 10, identity: 0.697

ggctcggtgagcttcacgcgatcctgtttgcgg	CRISPR spacer
tacagcagaagcttcacgcgatcgcgtttgcgg	Protospacer
 .*   . .************** .********

91. spacer 5.53|378622|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010016 (Burkholderia thailandensis 34 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggctcggtgagcttcacgcgatcctgtttgcgg	CRISPR spacer
tacagcagaagcttcacgcgatcgcgtttgcgg	Protospacer
 .*   . .************** .********

92. spacer 5.54|378683|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010871 (Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6002, complete sequence) position: , mismatch: 10, identity: 0.697

attcgccatctttggcgtgatccgggcgggcgg	CRISPR spacer
tatggccaactttggcgtgacccgggcgacttc	Protospacer
  * **** ***********.*******. .  

93. spacer 5.54|378683|33|NZ_CP010451|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010870 (Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6001, complete sequence) position: , mismatch: 10, identity: 0.697

attcgccatctttggcgtgatccgggcgggcgg	CRISPR spacer
tatggccaactttggcgtgacccgggcgacttc	Protospacer
  * **** ***********.*******. .  

94. spacer 8.3|3091114|33|NZ_CP010451|CRT matches to NZ_CP028345 (Vibrio parahaemolyticus isolate R13 plasmid pVpR13_55Kb, complete sequence) position: , mismatch: 10, identity: 0.697

gccaccaccttggttgccgccaccgtagtttcc	CRISPR spacer
tccaccaccttggtggtcgccaccgacaaacgc	Protospacer
 ************* *.********  .  . *

95. spacer 8.3|3091114|33|NZ_CP010451|CRT matches to NZ_CP028144 (Vibrio parahaemolyticus strain R14 plasmid pVpR14_56Kb, complete sequence) position: , mismatch: 10, identity: 0.697

gccaccaccttggttgccgccaccgtagtttcc	CRISPR spacer
tccaccaccttggtggtcgccaccgacaaacgc	Protospacer
 ************* *.********  .  . *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	351938 : 446240	74	Bacillus_phage(16.67%)	transposase,tRNA,integrase	attL 394012:394026|attR 426773:426787
DBSCAN-SWA_2	3004795 : 3063156	54	Streptococcus_phage(37.5%)	transposase,integrase	attL 3021040:3021055|attR 3066063:3066078

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP010451|351938:446240|DBSCAN-SWA
CGTGGATGAGCAACGCGCCTTTGATCAAGGACTCAAGGAAGAAAACACCTTGATCACAGATCTCACCACCTGTGCCAGGCTGAGCCATAACAAGGCATTACGGCTGATCAAGCTGTCGAAATCAACGGCGTATTACCGCAACAAGCCGCGTCCCTGTCCTGCACCGAAACCTGTCCTGCAGGCCGTGGCAGCACCAACAGCACCTGGTGTGGAACTAGCAGCACCTGGTGTGGAACCCACACCAGAGCCTTGGCAGGGGAAGGAGCCAGCAGTGTCGTCGGTGCGTCAAGCGTTGGCAGAACACGAACGCCAGTTCATTGTTGATGCGATCACCGCGTACCCACAACTGAGCGTTAGTGGGGTGTTTAACATGTTGTTTAACAAAGGCATCTACCGCGCATCACTACGTACATGGTGGCGTGTCGCCAAGCAGCACAAGTTGTTACACAAAGACCGAGTCAATGCCCTGTCCCCGGTGAAACGATCACCAACGCCACGAGTTAAGCCGAGGTTGGAAGCAACACAGCCTGGTCAGGTGGTGTGTTGGGATGTGACGTTCTTGCCGTCGCTGGTACGTGGTAAGACCTATGCGTTGCATCTGGCGATTGATTTGTTTTCCCGCAAGATTGTTGGGGCGAAGGTCGCGCCGACGGAAAATACCTCCACCGCGGTGGAGTTGTTAACGCAGGTGTTAGCGGATAATCCGGGTGTGGTGACGGTGCATTCGGATAATGGGTCGGCGATGACATCGACGAGGGTGCGGCGGTTGTTAGCGGATCATGGTGTGGCGTTGTCGTTGATTCGGCCGCGGGTGAGTGATGATAATGCGTTTGTGGAGTCGGTGTTTCATACGTTGAAGTATCGGCCGTTTTATCCGAAGGTGTTTGCATCGATGGATCAGGCCCGGGTGTGGGTGGAGGAGTTTGTGGTGTATTACAACACGGTTCATCCGCATTCTGGTGTGGCTGGGCATACTCCACAGTCGGTGTTTGATGGTAGTTGGAGGGCGGTGCATCGGTTGCGTGTGCAGGCGTTGGATGCCCATTACCGGCAGTTCCCGCAGCGGTATGTGGGACAGCCGGTGGTTCAGGAAGTTGCTGGTGTGGTGCGTCTTAATGGTGCGCGTGATGATGGGTCTGTACAGGAGAGGGTTGGTGGTGTAGCGTCGCTGTTAAGTGCTTGAGTTAGCACGTGTTCTTATCGCCCCCTGGTTCACAAACCCCTGGCAGCGAGCGTTTAATGCGTCGAAAAGTGAAATAGAGACCAAGGACCGGATTTCTAAGGTCGCGTTTGGTTTAATACGGCATCCGGCCTGAAAGGACAGTGTGGAACCCAAAAATCATGCCCTCGCAGAATCGTGTTTAAGGGGTTAAAACGCCTCGACCCACACTCTGACCCATCCGTGAAACTAGACCTCTTAAAACGACTTCTGGTTGGTGAGGTGTGAAAACCGCACTGCGGGGCCCAATTCACAAAAATCCATACGAGTGTGCACACCCGATTTTCACATCGCTTCGAGACCTCCCTTTTTGACACCTTAATTGTCTAATCCCGTATAGGTGAGAAATGTTGGACAAGTGTCTGTTTTTTGTGGGGGAAATCTGACTACGGTGGTAAGAAATAAGGAAAGAGATTACCATTATGTCTCAAGAGCAGCCTCAAATCGGCTCCCGCCTCTCTCGTGTCATTGAACAAGACGGCCTACAATTCCGCGATCTCGACGGCGACGGCGTACTTGTACCTTATGAAGATTGGCGTCTAACCCCAGCAGAGCGTGCCGCTGACCTGGTGAAACGTATGAATGTGGAAGAAAAAGCGGGCCTGATGATCATCGGTTCGCACTACCCCGGATACTCGCCTTTGGCGCCGGAGAGTGAAGGCAAAGACGCGGAAAAGTGCGAGCCTTTGCTGAACCCCGTCGATATGTGGCGTGAGGATAACCCGATCACGGGTGTTCCTTTCACCGAGCCTGTGCTGGCAACTTCTTCCACTGAAAATGCCATTAACCTGCGCAATCAGCGTTACTTAATTGTTCGTGACAACCTGCCAGCTCGTGAGCTTGCTACTTGGACCAATGCTGTTCAGGAAGTCGCGGAGCGTTCCCGTTTGGGTATTCCTGTTGTGTTTGCGTCGAATCCTCGTAACCACGTCGCGCTCGTTGCGCAGTTCGGTGTGAACGAGTCCGCGGGTGTGTTCTCTGAGTGGCTTGGCGAGCTGGGTCTTGCTGCGCTTCGCGATACTGAACTGATGGAGACTTTCGGTACCGAGGCTGCTAAGGAATGGCGTGCCGGTGGTGTGCACAAGCTGTACGGTTACATGGCTGACCTCGCTTCTGAGCCTCATTGGTCCCGCTTCAACGGTACTTTTGGTGAGGATCCGGAGTTGATCTCTGATTACATCGCTGCTGTTGTGCGTGGTCTGCAGGGCCCTGAGCTATCCAAGAAGTCCGTGGCGACCACCATCAAGCACTTCCCAGGTGGCGGCGTGCGCCTCGACGGCCACGATCCTCACTTCCACTGGGGTCAGACCAATGAATACCCAACCGAAGGCGCGCTAGGTAAATATCATCTGCCACCTTTCCAGGCAGCTATCGACGCTGGCTGCGCCTCGATCATGCCTTACTACGCACGGCCAATGAACAACTCCGCCAACCAGCTCGATCAGCAACTGTGGCAAAACCCGACCACGCAGTTCGAAGAGGTTGCGTTTGCCTACAACCGCACCTTCATTCAGGATTTGCTTCGCGACGCCATGGGCCACCGTGGGTACGTCAACTCCGACTCCGGCGTCATCGACGCCATGATGTGGGGCGTGGAGGAACTCAGCGAGCCAGAACGCTTCGCCGCAGCAGTGCGTGCAGGCACCGACATTTTCTCCGACATGGCTAACCCACGTCGACTGCTCGAAGCAGTTGCTGAGGGACACCTTGATGAGTCAGAACTGAACCAGCCGGTCCAGCGTCTTTTGGAGGAAATTTTCCAGCTTGGTCTGTTTGAGAACCCATACGTCTCTGAAGATGAAGCAGAAAAGATCATTGGTGCGCCAGAGGTTTCTGCATTGGGCAACAAAGCACAGCTTGATTCCGTCACCTTGCTGCGTAACAACCCATCCGTGCTGCCACTGGATCCTGCAGCAAGCCTGAAGATCTACCCATTGGTTACTGGCCGTACCAAGATCGACGAGGTTCAACTACAGCTGGAAGCTGCCATCCGCGCAGAACTCCCAGGGGTAACCTTGGTGTCTTCCGAGTCAGAAGCAGATCTTGCAATCGTGTGGGCTCGCCCTGAAATTGCACTGTTTGAAGATGACCTCGAAGGTGTTTCCCTCTCTGTTGACCCTCGTGCCAACGGTGTCGATGTGGAACGCGTTCAGGCTGTGGAAGCCGCAGTCCCAACCATTTTGGCTGTGAACTTCACCAACCCTTGGGTGCTGTCTGAGATCGAGCCTGGTGCTGCTGCCGTGGTGGGCACTTTTGAGATCAAGCCAGAGTTCCTTCTCAAGGCTTTGACTGGTCAAGAGGGTGGACCAAAGGGCAAGCTGCCATTGACTGTTCCTGCTTCCATGCAGGCGATTGCTGATTCCCCTCGCGATATCCCAGGCAAGTTCCTCGATGAGTCTTACACCTACGTGGACTCCGCAGGGATGGCCTACAAGTACGGTCACGGACTTAATTTCTAGATTGTAGGTAGTCTCGTGGGCACAACTGAAATCTTATTGAAAAGGAGTGTCCATGAGCACTGTCGTGCCTGGAATTGTCGCCCTGTCCAAAGGTGCACCGGTAGAAAAAGTAAACGTTGTTGTCCCTGATCCAGGTGCTAACGATGTCATCGTCAAGATTCAGGCCTGCGGTGTGTGCCACACCGACTTGGCCTACCGCGATGGCGATATTTCAGATGAGTTCCCTTACCTCCTCGGCCACGAGGCAGCAGGCATTGTTGAGGAGGTAGGCGAGTCCGTCACCCACGTTGAGGTCGGCGATTTCGTCATCTTGAATTGGCGTGCAGTGTGCGGCGAGTGCCGTGCATGTAAGAAGGGCGAGCCAAAGTACTGCTTTAACACCCACAACGCATCTAAGAAGATGACCCTGGAAGACGGCACCGAGCTGTCCCCAGCACTGGGCATTGGCGCGTTCTTGGAAAAGACCCTGGTCCACGAAGGCCAGTGCACCAAGGTTAACCCTGAGGAAGATCCAGCAGCAGCTGGCCTTCTGGGTTGTGGCATCATGGCAGGTCTTGGTGCTGCGGTAAACACCGGTGATATTAAGCGCGGCGAGTCCGTGGCAGTCTTCGGCCTTGGTGGCGTGGGCATGGCAGCTATTGCTGGCGCCAAGATAGCTGGTGCATCGAAGATTATTGCTGTTGATATCGATGAGAAGAAGTTGGAGTGGGCGAAGGAATTCGGCGCAACCCACACCATTAATTCCTCTGGTCTTGGTGGCGAAGGCGATGCTTCTGAGGTCGTGGCAAAGGTTCGTGAGCTCACCGATGGTTTCGGTACTGACGTCTCCATCGATGCGGTAGGCATCATGCCGACCTGGCAGCAGGCGTTTTACTCCCGTGACCATGCAGGCCGCATGGTGATGGTGGGCGTTCCAAACCTGACGTCTCGCGTAGATGTTCCTGCGATTGATTTTTACGGTCGCGGTGGATCCGTGCGCCCTGCATGGTACGGCGACTGCCTGCCTGAGCGTGATTTCCCAACTTATGTGGATCTGCACCTGCAGGGTCGTTTCCCACTGGATAAGTTTGTTTCTGAGCGTATTGGTCTTGATGATGTTGAAGAGGCTTTCAACACCATGAAGGCTGGCGACGTGCTGCGTTCTGTGGTGGAGATCTAAATGGCTCACGACGGATTGCGCGTAGAGAACATTGTCACCTCAGGCATCTTTGCCCTTGATGGTGGCGAATGGGAAGTCGACAACAACATCTGGGTTGTGGGAAATGATGATGAGGTTTTCATCATCGATGCGGCGCACACTGCAGCACCCATCATCGAGGCTGTCGGTGGACGTACTGTGAAGGGCATTTTGTGCACCCACGCACACAATGACCACATCACTGTTGCGCCTGAGTTGGCCAAGGAATTTGATGCACCGATTTTCGTGCACCCAGGTGATCAAATGCTGTGGGAGGAAACCCACGGAAACCTGGCTCATGAGGATTTGGCAGATCAGCAGAAGTTCCAAATCGCTGGAACTGAACTGATCGTGCTTAATACCCCTGGACACTCACCTGGATCCAGCTGCTTCTACCTCCCTGAAGCAAACGAGCTCTTCTCTGGAGACACTTTGTTCCAGGGGGGACCGGGAGCAACTGGCCGTAAGTACAGCTCCTTTGACACCATCATTGAGTCTCTCAAGACCTCAATTTTGGATCTACCAGCGGAAACCACCGTGCGCACTGGCCATGGTGATCACACCAGTGTGGGTGCTGAGGCTCCACACTTGGAGGAATGGATTAAACGCGGGCACTAAGCCCCGAACGATTAGTAGGCTTGGGCACCATGGATCTTAAACTTGGTGGCCAAGTCATACTTGTTGTTGGCGGTGCAGGAACTATTGGTTCTGAAGTTGTAAAACTCTTAACTGAAGAAGGCGCAACCGCGGTAGCGGCGTCGAGAAGCACGCCCTTATCTATTGACGCTTCGGATGAAGCGTCCGTCCGCGCTGGCATTGATCAGGTGATCGCAGAACATGGTCGCCTGGATGGGCTGGTTGTGTCTTCTGCACCCGCTGCGCAAACTCTTAGCGCGGAGACAGCAGATGATCCGGACACTGTGTTGGCTGCTATTGAAGGCAAAGCCATCACGTTTATGAAGGCTGCAACCGTGGCGCTCGAGAAGATGCGTGAGGCTGGATATGGGCGCATCGTTGCACTTTCCGGCATGAACTCATACAAAACGTTGAGTACTGCTGCGTCGGCGCGAAATGCTGCGCTGAATGTCGTGGTGAAAAATTTGGCGGATCGTCACGCGGGTACCGGAATTACAGTAAATGCGATTAGCCCGGGATTCGTGGTAGCTGAGCCAGACGCTGAGGTAAACCGCGCAAATGGCGACACCACGGTGGGGGAGGTTGCGGAGGCGATCGCGTTCTTGTTGTCGCCGCGCACTGCATCGATTTCTGGCGAGATTATTTCGGTGGGGCATAAGGCGAAGGGCGTCATCCTTCCTTAGCTCGCGTGAGCTTCCCAAGCGTAAGCACCCCCGTGTGAGGGCATAACGGCCGTTCTGTTAAAGATTGGTCTGGCCATTTCCTCCATATGGGGGTGTCCGCGTTTAACATGTCTGACATGGTGGCGAACAAACGGGCCCAGCGTAAAGTCTGGCTAGCGGTAGCTTTATCGGTCTTTACGGTCGCGTGGGGTGGCAATGAATTCACTCCCTTGCTGGTGTTTTACCGAGGTGAAGGGTTCTTTAGCAACCTGTTCATCGACCTTTTGCTGGTGTTTTATGCCATCGGAGTAGCAGTTGGTTTGCTGGCAGCTGGTCCTTTATCTGACCGCTATGGCCGACGTGCCGTCATGTTGCCTGCGCCATTGATCGCGATCTTGGGTTCCGCGTTGATTGCCTCGGGTGAAGAAACCGCCATCCTGATTGCCATTGGTCGAGTGCTGTCGGGAATTTCGGTGGGCATGGTGATGACAGCGGGAGGTTCCTGGATTAAGGAGCTTTCATCGTCGCGGTTTGAGCCAGGGGTGAAAACCAGTGCTGGTGCAAAACGCGCATCGATGTCTTTGACCGGTGGTTTTGCGCTCGGCCCAGCGCTTGCTGGTGTGATGGCACAGTGGCTGCCACTACCTGGACAGTTGGCGTATGTTTTGCACATTATTCTCACCCTGATTTTGTTCCCGTTGCTTATTACAGCGCCGGAAACTCGTCAATCAGCGCACCTGAAAACTAAGGGATCATTCTGGTCAGATGTGCTTGTGCCATCTGCACTAGACAAGCGATTCTTGTTTGTGGTTGCTCCAATTGGACCGTGGGTTTTCGGTGCGGGCTTCACTGCCTACGCAGTTTTGCCGTCGCAGTTGCGTGACATGGTTTCTGCACCCGTTGCGTATTCTGCGCTGATCGCTTTGGTTACCTTAGGTTCTGGATTTGGTATTCAACAATTCGGTCCTCAAATCATGGGCACCTCTAAAACTCGCGGGCCGATTTTGGCTATGTTCGTCACAGTCATCGGCATGATCGGCGCGGTGATCGTGGTGATGAACCCTCATCCATGGTGGGCGCTAGTTGTCTGCATGGCCCTCGGTCTGTCTTATGGCCTGTGTATGTTCATGGGGTTGGCGGAAACTCAAAACATTGCTCCACCTATTGATATGGCAGGCCTGACGGGTATTTTCTACTGCCTGACGTACGTAGGTATGGTCTTTCCAGCCTTGATGACCTGGTTGAATCAATGGCTCAGTTACCCGTTCATGCTGGGCTTTGGTGCGGTGATGGCAACTATTTGTCTGATCATTGTGAGTTTTAGTGCACGCCGATTCTGAGAAACAACTAAAGTGAGCCACATGCGCACAGTAGTTACCGGCGGTGCCGGCTTCATCGGATCCCATCTCGTTGACCTTTTGATCAAGGAAGGCCACGAGGTCGTTGTGATCGATAACCTCTCCCGCGGACGCCTGGAGAACCTCTCCGATGCGGAAGCCACCGGAAAACTCACCTTTGTGGAAGCCGATCTGCTTGATGTGGATTTCAACGAGTTCCTAGGAACCCACAAGCCTGAGGTTATTTTCCACCTGGCAGCGCAAATCGATGTGCGCCACTCTGTTGTAGATCCTCTTCACGACGCGGAAACCAACATTTTGTCCACCATCCGCATCGCTGACGCTGCCCGCCAGCACGGTGTCCGCAAGGTTGTATTCACCTCATCTGGCGGATCCATTTACGGTGAGCCTTCGGAATTCCCTGTTGATGAAACCGTGCCTGTGGATCCGCATTCCCCTTATGCTGCTTCCAAGGTGTCTGGCGAAATTTACCTGAACACTTTCCGCCACCTCTACGGTTTGGACTGCTCCCACATCGCGCCTGCCAATGTTTATGGCCCACGCCAAGACCCACATGGTGAAGCAGGAGTAGTGGCCATCTTCGCGCTGCGTCTTCTGGGAGGCCTGGACACCAAGGTATTCGGCGACGGCGGAAACACCCGCGACTACGTCTACGTCGGCGACGTTGTCCGTGCCTTCTACCTGGCTTCTGGGGAAATCGGTGGGGGAGAGCGGTTCAACATCGGCACCTCTGTGGAAACCTCTGACCGCCAGCTGCATACTCTCGTGGCTGCTGCGGCGGGTTCCAAGGATGATCCTGAATATGCACCTGCACGTCTCGGCGATGTGCCACGCAGTGCACTCAGCTTCGGCAAGGCCAAAGAGGTGCTTGGTTGGGAGCCTGAGGTGAACATCGAACAAGGTGTGGCCAAGACTGTGGAGTACTTCCGCACCCACTAGGGGAAAATCCACCACAAATCGCTCTGATCAGCGGAAACGTGGTGGGTTTTTGCATTTTCCGCACTCAAAAACGCAAGGATCCACCACAGATCCCAAGATTCTTCAGGGATGTGGTGGATCCTTGTCCTGGAAGCTCACAGCTACCCCGAAGGGATTGATGGGGTCCGCTGACGGGGAAAATTCGTCCCCGGCACGCGATAAAAGGCCGATTTTGGTCGAAAATTTGCGCTAATTCCGGGAGATTATGCAAAAACTCGTTCGATTTAGGGGTTTTTGAGCGATCTGGGACGAAAAGTTGAACAGCCAGCCCACAGGAATCACACCTGCAACACCAGCCCCAAAATGGACCCCCTCTAAAACCGTCTCTAAGCGCTCAAACGGTCCCGACCCATACAAACGCTCATTCGATAGGGTTCGAGCCCTTAAATCGCCCCCAGTGGCCAAGCGCTTTCCTAAGCGGGGTCAGAACCCTGGGAATCCTCCGGCAGCACCGCATTTTGCAAAGCGACAGCGCGGGCCAGCTTGGAATAACGCAGCTCTTGTTCACGGAAACGCACATAACTGGACAGCGTGGTGAACATAAATGCCACAACCAGGGCGTAAAGCATGAGGTCGGTGCCGCGGTCCACGCCCACAAAGTTGGCTAGTTGGGTGAGGTCATCGGGGCGGATCACTGCCCATACTGCGGCGAAAATGAATACTACGAAGCCGATTTTCACCCATGCTTTGGCGCGGGCTTTACGGCGGTTTCTGAGGAAATATAGTGCCAGTGCTGCGGTTGCCAGGAGAAGCAGTATCTGGATGATGATTTGGGTGGTGGTCTGCGTCATGGGAGTCTCCTCGCTAGGAAGCCGTCGGCCAGGATGTTTACGCCGTTGAGCAGGGATTGTCCCTTGCTCATGGAGTATTCGGTGTAGAGGATGTCTACGGGTTCTTCTGAAATGCGCCAGCCGCGTTCATCGATTTGGTCGACGATTTCGGATGCATGCGACATGCCGTTCATGCGGATGTTCATTTCCTGCGCCACTTTTTGGTTGAATACGCGCAGGCCGTTGTGGGCGTCGGTGAGCCCGAGTCGGCGGGTTTTCGGTGACAGCAGGACCACGGTGCGCAGCACAAGGCGCTTGATTAGTGGCACTTGATCATCGGCTTGGCGTGGGCGTCCAAAACGCGTGCCGACGATAATGTCCACGTCCTCGGCACGCAGTCGCTCCACCATGCGGACAACGTCTTTCACTTGGTGTTGACCGTCGGCGTCGAAAGTCACAAAGTATTTTGCGCCGGGTTGTTTGCGTGCGTATTCGATGCCGGTTTGGATCGCGGCACCTTGTCCGAGGTTCACGGGGTGGTTGACCAGGTGGGCGCCGGCCGCATGGATTTCTTCCGCGGAGTTGTCCGGGGAGCCATCGTTGACCGCAACAATATTAGGGAATGTTTTGAGTGCGTTCTCTAAAACTTCCCGGATAACTGTTGCCTCGTTATAACAAGGTACGACTAGCCAGGTGTCTTTAAAGTCGCTGTTTTTTGATGCATCCATGATAGGAATAGAGCCTAGTGCATGATGGCCGATTTTCCTGTTAGGTGCCACCGACCCCAGTGATGATAACTTGATTGTCATGAAATCCATTGATCTTGAGCAGCTGGCGGGCACGCAATCGCGCACGTATCAATCGCGAAAGATCACCGATGAGATGGTTGCCCGGCCGGTGCATGTGGCGATCGCGTTGTGGGAAGTGCCGTGGGAGTCGGCAAAATCCGGCAAGATTGAGGGGTGGGTCATTGCCGTGGATTCGCCGCGTGGGCGGTTTGTGCGCAGCGGGCAGACCAAAAATGGCGACGCCGTCAACCGGACTGTGTCGATGCTGAAATCAGCGTTGAAAGGGGTCCGCGGGAAGGCGTGGATTGTAACTGGGCGTCGACAAGCAGCTTTACGCGCAGCCCTGGTGCGCGAAAACTACCTGGTCACCGGAAGCTTCGCCGAGCAAAATAGGGCCGGTGTGAAGGCGTCGGCGATCTCGCGCCGCGCCGAACAATCCGCGCTCTACAAGGCAAAAAAAATCGGCGAATTCGCCGAACGCGCCCCACGCGTCAAAGAGCGGCAAGAGGCACATTGGTGGCCACGGTTGTCACGCACGCAAGGCACCGCAGGCGTTTTACGCTTAGCGACGGACGCCTCCACCGATGGGGTCTTCCGCGGCGCCATGTGCTTCGTAGCCTCAAACGGCGACTACCTCCTGGAGACCCAAGACACCACCGCAAGCTCCGACGAGTTAGAACTCGAAAGCATCACTCACGCCCTGATCTACCTCAAAACCATCGGCGCGACCCAAGCCATCATCGAATCCGACAGCAAAGCCGCACTTGAAGCCATCGACTTCATCCTCAACACCCGACCGCGCCGGGGCAGGTGGCGCGGCATCACCGCACGCGCCCGCAACCGGTTCCGGGATGCCTGGGAGGCGCTTATCGACGATTGCGTTGTGGAATTATCCCGCGTACTAGGGCACGCCGGGGATCCACTGAACCAAGCAGCCGACCAAATCGCATACATGGGCATGCGCGCCGTAATTTTTGAACAAAAATCCGCACACCCCACATTGCTCAAAGGAATTGACAAGGCGCTTCGCAAGGCCGAGTAAGGTGGGCAACGAGTCGGTGAGAGTATGAGGAATATTTAATGAGCAACAAACGCATCGGTGTAGTGATCGTTTCCTACGGACACGAACAAGATGTTGCCAACCTGGTAGACACATTTGCAGATCAGCTAAAAACTGGTGACCGCGTGGTTGTCGTGGATAATCGCAAGCCTTGGGTGTTAAAAGACACCGTGGGGGAGCGCCTGGAAAAACACGGCGTGGAGATCATCAACCACGACAATGGTGGCTTTGCCGCTGGCTGCAACGTGGGCGCAGCGCACATCGTGGACGACGTTGACCTGCTGTTCTTCCTCAACCCCGACACAGTGATCGACGATCCCACCCTGTTCAATTCGCTGAGACGCGTCGATGAACAGTGGGCAGCATTCATGCCGTACCTGCTGCTTCCTGACGGCACCATCAACTCCGCAGGCAACGCCCTGCATATTTCCGGACTGTCGTGGGTGACTGGTCTGGATGAAAAACCAGTTGAAGGCTCATCTGAAGTTACCGATATTTCCATCGCCTCCGGCGCCTGCCTGGCCGTGCGCGTGGAATGGTGGAAACGCCTCGGCGGCATGGAAGAACTGTATTTCATGTACCACGAAGACACTGACTTCTCCGCCCGCTTGCTGCTGGCCGGTGGTCGAATTGGTCTCCTGCATTCCGCGTATGTCACCCACCACTACGACTACGCCAAGGGTGACTACAAGTGGATTTACATCGAACGAAACCGACACGTTTTGCTGCTCAGCGTGCTGCCGCTTCCATTGCTGCTCATGCTGATCCCGCAGATCCTCGGTGTGAACCTGGGGCTGTGGGCGATTGCCGCTAAGGAGAACCGAGTCGGGCTTAAAGTGAAGTCCCTTCGACTCCTGATCCGCGATCTACCAGCGATTTTCAAACTGCGTAGGAGCACGCAGGAGCTTGCCGAACTCACACCATCGCAATATCTGGCAAAAATGGAATGGCGCCTAGACAATCCCAACCTAGGCAACATTGGATCCAACAAGATTGTTGCGACTGTATATAAGACCTATTACAAGTTGTGTATGAGTATCCTGAAATTGCTCGCTTAACACCCCATAAAGAGGGTGAAGATTTAAGTTTAGGTGCGGTCCGGGTGAACAGTACATAAATATCATCTTTCGCTAATGGAAAGCCCCAGCTCACCGAATTCTCCATTCGTTTTAATTGCTTCGTTAATTAAAACGCCATCTAAAAATCGGCTCGTTGCCGGTTCTTTTTCAGGAGAATTTAATGAAGAGGCTTTCCCGTGCAGCCCTCGCAGTGGTCGCCACCACCGCAGTTAGCTTCAGCGCACTCGCAGTTCCAGCTTTCGCAGACGAAGCAAGCAATGTTGAGCTCAACATCCTCGGTGTCACCGACTTCCACGGACACATCGCTCAGGATCTTTCAAAAGGCGAGATGGGTGCAGCTGGACTTGCTTGTTATGTTGAGTCCGAGCGCGCAGCAAACCCAAACACCAGCTTCATCACCGTCGGTGACAACATCGGTGGTTCTCCATTCGTCTCGTCCATCTTGAAGGATGCTCCTACTCTGACAGCACTGAGCACCATCGGCGTAGATGCATCCGCACTGGGTAACCATGAATTCGATGCCGGCTATGAGGACCTTGCCGGCCGTGTTTCCTTGGACGGCACAGGCTTGGCTCAGTTCCCATACCTCGGCGCAAACGTTGAGGGTGGCACCCCTACTCCTGCAGCTTCCGAAGTTGTTGAACTTGGTGGCGTGCGCGTTGCCTATGTTGGTTCCGTAACCGATGAAACCTCCACCCTGGTTTCCCCAGCTGGAATTCCTGGCATCACCTTCACCAATGACCTCAGTGCAGTAAACGCTGAAGCTGACCGCATTATGGCTGCAGGCGAGGCAGATGTTGTTATCGCGCTGATGCACTCCCCAGCTCGGGCAACCGACGCATTCTCCACCAACGTTGACGTAGTTTTTGCCGGCCACACCCACGAAGAGCGCGTTGAAACCGGCCCAGCCCGCGATGGCAAGCAGCCATTGGTTGTCATCCAGGGCATGGAATACGGCAAGTTTGTTTCTGACGTTGAGATCTCCTATGACTCCACTGCCAAGAAGATCACTGCAATCGAGGCAGTAAACGTTGATGCAGCTACCGCTTCTGGTGCTTGTGGAGTACCTAATGCGCTAGTGACTTCAGTAGCTGGCATTGTTGATGCTGCCAAGATCGCTTCCGACGTTGAGGGCGCAAAGGTTGTCGCCACCATTGAGAATTCCTTCTTCCGTGGTGCTGATTCCGCAGGTGAAACCGGATCTAACCGCGGTGTTGAGTCCTCCCTAAACAACCTCATTGCTGAGGCTGGATTGCAGGCAATCAACGCTCAGACTCCACTAAACGCTGACATCGGAGTGATGAACGCAGGCGGTGTACGCGCTGACCTCGAGGCTGGCGAGGTCACTTTCTCTGAGGCATTTGCCACCCAGAACTTCTCAAACACCTACGGCGTTGTAGACATCACCGGCGCCGATTTTATTGAGGCGCTGGAGCAGCAGTGGAAGGATCCAGCAGCTGACCGTCCTCGTCTGGCACTGGGTCTGTCCAATAATGTGCAGTACTCCTACAACCCTAACGCCGCACAGGGCGAGCGCATCACTCACGTCACCATCAACGGCAAGCCAATCGATGAGACCAAGACCTACCGCATCGCAGGATCCACATTCCTGCTCAGCGGCGGTGACGGCTTCACTGCTTTCACCAACGGCACAGACATTACCGATTCCGGCCTCGTTGACATCGACCTCTTCAATTCCTACCTCGCCGCCAACACTAGTGTGGACGTCCGTGCTAATCAGGCTTCCGTAGGCATCGAGCTCTCTGGGACAGCGCTTGCCGACGATTCCAGCCTCATCCCTGGCAAAGAGCTCACTGTTGATCTCTCCGCACTGTCCTACACCGGTGGCGAAGTTACCCCCACTACTGTCACTGTGACCTTGGGTGCTGAGACCGTGACTGTCCCCGTGGACAACACCATCATTCCTAAGCTTGATACTACTGGTACTGCAACTGCCACTTTGATAGTTCCAGCAGGAGTAACCGAGCTGAAGATCGAAACCGATGCAGGCACCACCTTCACCTTGCCTGTTGTTGCAACCTCAAAGCCTGCAGATGGATCTTCCGTTGGATCCTCTGCCGGTTCCCTTGTTGCAATCCTTGGAGTTTTGGGCGCGCTTGGCGGGCTTCTTGGAGTCTTCCTACACTCCCCACAGGGCGCTCCATTCCTGACCCAGCTGCACGCATTGATCGACCAGTCCAAGCCATAATTAGTTCCAGCCGAATTCAGCCCGTCTCCTTTTTGAGGCGGGCTGAATTCGTTTCCTATTAGTCACCTGTTGCGGGAATAAGAAATCTTGAGAGTGCTAACTTTTTACGAGTATTGCGTGCTTAAATCACATGGTCAAAGTTAGCTCTGTGAATTTCCTTAAGTACTTTGAATTCCTTAATCATGTGACGTTGGGTATTAATTGGCCTTGAAGTAGGTTTTGAAGGCCCTCTCCTGGTTTTCGCGCGGGATTTAATACTTCTTAAATTGAGATTTTCGATTCCCAAAGCGTAGGTACTGCGACGAAACGTCCTTACATTTGCAGGCGGAACTGAAGACGATCCTAACTATTAGGAACGCTTAGTCAACGGAATAGGCCTCCCCATCCGAGAATAAGCCCAGCAGCTTCATGACGCCGGCGGATATTCCTCTTCACGACTCGTAACTAGAGGTCTTCGTGGGCAGTCCGAGACGGTCACGAGGTTGAACCATGTCGCACTCATCTTAATTTCTAAGGTTTGGTTTCGTTCCTACGCGCGACGGCGCGTCCGTCATTACTCGACAGCGCAACCACCGGACGGGCTTCGAGCTTCGGGTGAAAGACCTATTCACGTCAACGTGTGCGATGTATTCGCTCCGCTGCGGTATGCCGTGGGAGTGGAGAGCTGTTTGATGGTAATCTCCCGGTCGCGTGCCTGCACGGAGCAGTCAACAATCAGTTTATCCCCATCGCTGACCCCCACCACCTGCATCGACTCATCAGACACTGCGCAATGAATGTCAAGGCATGCTCCCTGATTAGTATCTCGGTCAGATCAATCTTCGTATTGGAGGAGTCCTGGGCAAGTGAAAGGTATGCGGAATCGCCGACCAATTCCATGGCAACGTGGCCGGAACTCACCTACATCTATACGCCAGAGAGGAAAATTCGCCGGGCTATATGTCTGTCACCCATACTGTGGCTTTGGCAGAGCATGATCGGTCTCGGCCGTCCACGCAGTGGTGGCAATACCTCAACGAAGTCCTGGTATTCCAAGACGCCCGCCACCAGATGCCCAACATCATCTCTGGGAGGAGTGAATTTTTCTCTCTCGGGTGATGCTGAGGTCGCTTGAGATAAGGGCGAGAATAGGAAGGGGATTTGTCCGATGCCTGATTGCAGGAGTGAGGATGTTCATACATAGTAAAGCTGTGTCCCACTCAACCTCGCCCCTGCGCGGCATCGCAGGGGGATTACGCACGGAGTCTGGCTCGGCCGTGCTGCTCATCGTCGTCACGGTCTTCGCCCTCGTCTGAGCGAATTCGCCGTTGTCCTTTTCCTATTTCGACCTGTGGCATCAGAACATTGGTATCGACGTCGGCCCGTTTGGACTGCATATGGATCTCCACCACTGGATTAACGATGGACTGATGGTCGTGTTTTTCTTTGTCGTGGGTCTCGAGGTACGCCAAGAATTTGCACACGGGGCTCTACGGGACAGTAGTCGTGCTCGTTTGGCTGCGATCGCAGGCATTTCGGGTGTTGTTTTGCTCGCAGTGGTGTATGTCCTAGTCGTGGGCTCGTCCGGCGGCGAGGGGCTCCAGGGGTGGGGAGCGGTTGTCGGCACGGATACGGCGTTCATGCTCGGTGCTCTTGCGATCGTTGGCCCTAGATTTTCAGGGCAGTTACGCGTTTTCCTTTTGACCCTCACTGTGGTCGATGATTTCCTTGCGGTGTCAATCATTGGTGTGTTTTACAGCGACGAAATCCGGCTCGTTCCGCTGCTGATTGCTCTAGGATGCCTTGTGGCGTTGTGGCTGCTGGATCGTTCTCGGCAGTCGAGTAGCACCCCGTACGTAGGAATCGTCATTGTGCTGTGGCTAGCGACGCTGTCCTCTGGCGTCCATGCTTCGCTGGCAGATATGATTGCTGGGCTTTTGGTCCCTGCTTATCCGACACGGCGACATAAAGTGGTCGCCGCTCGACAGCTGTTTCGGGACTTTGGCAGTCACCCAGCGCTTCCTCGGCGCGTGCCGTGGGACGGGGGGTTGTCTAAGGGAGTGTCAGTCAACGAACGGTTGCACGATTACCTTCGTTTACCCACCGCATTAGTAATCGTGCCTATCTTCGCCTTGTCGAATGCCGGGGTTGACCTGCGCGGTGGAGTGATGGCCGAAGCTTTAGGCTCGTCGGTGACGTGGGGTGTTATCGCGGGGCTCGTGTTGGGCAAGTTCCTCGGAGTCGGGATTGCCACGTTCCTTGCTGATCATCGGCATTGCTTTCGACCCTTCCTCCGATCTGGGACGTCAGGCGACGGTGGGAGTTCTGGTTGCGATGGTGCTGGCCGCTGTTCTGGGGTGTACGATCTTCAAGGTTGCAGCCCGTCGGTGGGGAGAAGAGACAGCGGATCTGCCGATGACGCTTGACTCCGCGGTGGATCCTGAGGTGGACCATATTCGCGGGCTTGAGGACGCCCAGCTCACCCTGGTGGAGTTCGTAAACTTTGAATGCTCGTACTGTGCGCATGCCACCGGTTCGTGGGAGGATCTCCACAAGCGTTTCGGGGATGATTTACGCTACGTTGTGAGGCATCTTCCTCATCATCCTCACGGCCCACTCGCCGCAGGGGCCTCAGAAGCGGCCGCGAAACAAGACATGTTCTGGCCGTGGCTTGACTTCGTATTCACTAAACAGCATGCCCTCGAACGCGAGGATCTCATCGGTTACGCGACTGAACTCGGTCTCGATGTCAAGGCGTTCGTTAAAGACCTAGACAGTGCTGAAGTTGCCGCGAGGGTCGAACGGGATGTTGCTAGTGCTGCAGCAAGTGGCGCTCATGCGACCCCGACGTTCTTCATTGATGGTTACCGGATGACTGGAAGCTATGATGCACGTACATTGACCGCGACGTTGGAATCTAGTCGTCGTGGGGCACGCACCAAGGAGAGTCAGGCCTAATGTTGATCATTGGGCTTAAAACCAGGTGGGGCAGGGGCGTTCGATTGGTTTCACTACCTAGTTTTCGCAGCTGCTGACGATGATGGTACAAGTGAGTTCGCTTTTGCCGAGTTTGTGATGTGGGTTGATCTCCCATGACTTGCGACTACAGATGGCCGCGGAGCGCGCCGGGACTGGAAAACGGTGCGGATCCGTCAGGGGCCTGTCGCACATCTTTCTAAGGGTGGGCCGCAGCGAGGCACTCGAGTAGCTGATCCGATAATGGGACCATCCCCGCCTGAGCGGGGAGAACTATGGTTCTTTAGTAATCCTGATTTGCTGCGCGGGACCATCCCCGCCTGAGCGGGGAGAACGGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAGGGACCATCCCCGCCTGAGCGGGGAGAACGGGAAGCGCTTGCCGAGTACTAAAGGCTTGAGAGGGACCATCCCCGCCTGAGCGGGGAGAACACATCGCGATTACGCAAAGCTGCAAGCATAGTGGGACCATCCCCGCCTGAGCGGGGAGAACGCCACATGCGCCACCACCTCAGCCGGGGCACCAGGACCATCCCCGCCTGAGCGGGGAGAACTTTGGCACTCTTTCCTGTTTAGATGGTGTGGCCGGACCATCCCCGCCTGAGCGGGGAGAACACGTCGACAAGCTCACATCCAAACTTTCAGGACGGACCATCCCCGCCTGAGCGGGGAGAACGAGGTTAGTTTTAACCCAGAGATGGTCGAGCTTGGGACCATCCCCGCCTGAGCGGGGAGAACCAGCGACCAACGTTAGTAAAACCTGGGCACAGCTGGACGATCTCCGCCTGAGCGGGGAGAACCGGTAAAGCACCACTGTCGCATACGCATAGCACGGACCATCCCCGCCTGAGCGGGGAGAACCTTACCTAGCCACCCCGCAGACACGTGCCCTTGGGACCATCCCCGCCTGAGCGGGGAGAACCCGAGATCCACAGGGCCGATGCTGCTCGATGTGGGACCATCCCCGCCTGAGCGGGGAGAACTGCTCTTCCCAGAGCGTGCCCACATCCATAGTCGGACCATCCCCGCCTGAGCGGGGAGAACGATGTGCACCCCAGAACCAGCTGCCTAAGATCCGGACCATCCCCGCCTGAGCGGGGAGAACATGCGGTCGCTGGCTTGCTTAAACGTGACATAGGGACCACCCCCGCCTGAGCGGGGAGAACAAGCCCCGCGTCATTGCGGGGCTTGAAATAATGGGACCATCCCCGCCTGAGCGGGGAGAACTCAGCACTTCCCAGGTGAAGATTGGGACGACAGGGACCATCCCCGCCTGAGCGGGGAGAACATGATCTTACAGTGCGAGCGACGCTCGGCCCCGGGACCATCCCCGCCTGAGCGGGGAGAACTGTTCCAAGCTGCGAAAGCATGGTTTCCAGTAGGGACCATCCCCGCCTGAGCGGGGAGAACTACACCCGCTAGGCCAGGTGCGGAGAAAGGTACTGGACCATCCCCGCCTGAGCGGGGAGAACTGATTGGTTCGATGGCCGATTCATTGACTGTGGGGACCATCCCCGCCTGAGCGGGGAGAACGATTGGTGGTGCTGCTCAGGCAATAGGTGGTGCGGACCATCCCCGCCTGAGCGGGGAGAACGCCCAGTTGCCCCGATCACCATGACCAGCGCAGGGACCATCCCCGCCTGAGCGGGGAGAACCCACATATAGGAGGGGCGAAGTTTAACCAGCAGGGACCATCCCCGCCTGAGCGGGGAGAACTTTCAGAGGAAGTGGCAGCCGATGCTGACGGAGGGACCATCCCCGCCTGAGCGGGGAGAACCGGTCCCCAAAGTCCGGGGTAGTAACGACCACCGGACCATCCCCGCCTGAGCGGGGAGAACCGCCTTGTCGACGGCCACGGTAATGGGGGAGACGGACCATCCCCGCCTGAGCGGGGAGAACAAAAGCAGGCAGTAGAGCAGCGCCACGCTCGTGGGACCATCTGGAGCCGAGACGACACGTCGAATCGGCGATACAGAGCAGCGCCACGCTCGTGGGACCATCCCCGCCTGAGCGGGGAGAACACATCACATCTGGCCGAATCTTAATCAGGAGGCGGACCATCCCCGCCTGAGCGGGGAGAACTGAGCGCATTGGGTATCGCAGCAGGCGCGACCGGGACCATCCCCGCCTGAGCGGGGAGAACAGGTAAAAACAAGTGCCGATCAGGTAGACAAACGGACCATCCCCGCCTGAGCGGGGAGAACGACTGTCCTGGCTGGTGTTCCGGAGGCTACTACGGACCATCCCCGCCTGAGCGGGGAGAACTGGGGCTTGATGTGGAAGAAATTAAGGCTGAGCGGACCATCCCCGCCTGAGCGGGGAGAACCCTGAGGTTATGCAGCTACTTAAAGATGTGAGGGGACCATCCCCGCCTGAGCGGGGAGAACATTGCTCATATGGGCGGGCAGACTGCTGCGCAGGGACCATCCCCGCCTGAGCGGGGAGAACATCTGTTCACCCTTCCGGTACGCATTCCACGCCGGACCATCCCCGCCTGAGCGGGGAGAACAGCAGGCGTCCGACTTGCACGCGATTACGATCCTGGACCATCCCCGCCTGAGCGGGGAGAACACCCTGTATATCTCGGCATTCAGCCTGCCACCCTGGACCATCCCCGCCTGAGCGGGGAGAACGAACCTTGGTTGCGTCCGCTTCGCCAGAAGAACGGACCATCCCCGCCTGAGCGGGGAGAACTTCGACCCCTCCGCGATTAAAAGCGTCGATTCGGGACCATCCCCGCCTGAGCGGGGAGAACATATTTCGGTTGGTTTGTGGTGGCCTGGTGATGGGACCATCCCCGCCTGAGCGGGGAGAACCAACGACCATCGCGAAGCTGAACGGATTCATCCGGACCATCCCCGCCTGAGCGGGGAGAACAACAAGAACGGCCCCCGGGAGTGCTGGAAACACGGACCATCCCCGCCTGAGCGGGGAGAACCAACCTTGAGTTTATCTACCTGATCGGCACTGGGGACCATCCCCGCCTGAGCGGGGAGAACCGCTTTGCGATCTGGATTCGCTCTTCCTTTGCCGGACCATCCCCGCCTGAGCGGGGAGAACCAAAAGAACATTCGACTCCGCAGCCAACACACGGGACCATCCCCGCCTGAGCGGGGAGAACCATCCCCTCACTGATGGTGTACCCGGTGAGTAGGGACCATCCCCGCCTGAGCGGGGAGAACGGTAAGCTCACCCCACGCTGTGTGTGATCAACTGTTTGTAGGCCAGTTAAGCAGAAGAACCCGGCCAAATCAGCGGCTGGTTTCCTGCCAAAAAAGCACGAAAAACCAGCCACCTCCCCACACCCACCAGGTGGCCGGTCCTCACCGCATGCTCAAGTATCTATGTAAAGCCTGACGGTCATGTGCACCGCCACCGTTAGATAAGTTCCTCCTCGACGCTTCCCAACCCTTTTCACAAGCGGAGCGTCTTAACAGGAAGGAACACGAAAGAAGATGACGGTACACATGACCGTTGTAGAAGATATCAGGAGACTCGACTCTCAGGGAGTTTCCAACCGTGAAATCGCCCGCCGGCTTAGTATCAGCCGCGACACGGTAGCGAAATACACCAACATCGAAGACTTCTCACCAACACCACCCACACCCACCAAACGCCCAGGTATCAAAGCACTCGATGGACTCGACGTCATCATCAACGGCTGGCTTGAAGACGATAAGAAACGCCCCCGCAAACAACGTCACACCGGCCGACGTGTCTTTGACCGCCTCGTTGCCGAATACGACTACACCGGCTCTTATTCCACAGTGTCGCGCTATATCAAACTTTGGCACCAAAACCACCGTCATCTCAGTGACGGTTATATCGAACTGACCTGGACGCCCGGTGTGGCTCAAGTTGATTTCGGCCAGGCTGAAGCAATCATCGCAGGTCAACGCATGACGCTGCATATGTTGGTCGTCACGTTCCCGTTTTCGAATATGCGCTTTGTCCAGGCATATCGCGGGGAAACCGCGGAATGCGTCTGTCACGGACTGCGCACCATCTTCGAACACATCGGTGGCGTACCCCGCCAATTGATCTTCGATAACGCCACCGGCGTCGGGCGACGTACCGGCACCACGATTATTGAGTCGAAGCTGTTTTCCGCGTTCAAGCTGCATTACCGAACGTCAGCACGTTATTGCAATCCTTATTCCGGTAATGAGAAAGGAAACGTCGAAAACGCAGTCGGCTTCCTGCGCCGCAACCTCATGGTCCCTGAACCTGTTGCCACCACCTTGACTGGGCTTAACACCACGTTCCTGGCTCAGTGTCAGACTTTGGGGTTAAAGCCACATTGGCGTAAACACCAGCCCATCATCGAGTTGTTTTCCGAAGACATCGCTGCATGCCTGGAGCTTCCTGGAGTTGGGTTTGATCCGGTGCGCTATGAATCCCGCAAAGCCGATAAAACCGGCACGATTACCGTTGAAGATAATTTCTACCTCGCTGGTCCCTCTTTTCATGATCGGCTGCTCACCGTAGCGATTCGCCATGATGTCATCGAGATTTTAGATGAAACCTCACGCCCGATCGTTACGTTTCCCAGATCCTATGATCATCAAGATACGACCGTGTTCACTCCCTTATCACTGCTTCCGGCGCTGATCACCAAACCAGGGGCCTGGGAAAACTCACCTGTACGCACCTTGTTGCCCGATACTGTCTGTGGTGTGCTGGATAAGGCTGATGCCACGGACCGATCTAGGATGCTGGCTGGGATCAACCAGGCCAGCACCGCTTTCGTCCTTTCCCAACGCCATTGCCGCCTGTGAGCAGCTCATCGCGGTCGGCCAGGATCCTACTGGCCCAGGCCTGGGGATGCTTGCCCGGCGTATCGCCCAAGACACCGAACCCTCAACGCCCGAAGTGGATCTATCTGTCTATGACCTGCTGCCGGCACGCCGTCAAACACACCACCGCAATGATCAGAACGCGCAGGTGGGGGCATGACCGAAGCAATCACCGCGACCGATATCATCACCGCAGGTAAAGCCACCTCACTCACGGCCACCGTGCTGGCGGAATGGGCAGAAAAAGGCACACCGAAACAACGCGAATACTTACACGGACTCCTGCTTGCTTCAACAGCAATCCCGTCATAGTGCACGTAGTGCCAGGCTGCTACGCGCAGCAAAATTGCCGATGAACAAAACCCTCGAAGGCTACGACTGGACCAACATCAACTTCCCGGACAGCTATGGACGTGAGAATCTTCGCTCCCTGGATTTTCTGGATTCCGGTGGTGATCTGGTCTTGTATGGCGATGTTGGTACCGGGAAAACTCACCTGGCCTGTGCTCTTGTTGCCCACGCCTGTCAGGAAGGTATCCCTGCCAGATTTTTTACTACCGCCTCACTGGTAGCACATCTACGTCGAGCGAAAGACGCTGACCGGCTTGATAAAGAATTAATCAGTCTGGGAAAGAACCGTCTGCTGGTCATTGATGAATTCGGCTATCGACCCATTGATACCGAAGGTGCACGGCTGTTGTTCCAGGTGATCGCTGATGCGTATGAAAGGCGCAGCTTGATCTTGACCACCAACTTGGCTTTTTCCAAATGGGGTGCGGAGTTTGGTGATGATCACATGGCTGCTGCTGTGATTGACCGGATTGTCCATCACGGGAGGTTGCTGCACTTTAGTGGAGAATCCTACCGCGTCAAGCATGCCTTGATGAGCTAAGTCCTTTTACTTAATCCATGATGATTGGAGACTTTTTCTCATGACCATATCTATTCCTACAACTACCGAAGACCGGTTATGTTTTCCTCGGGATGAGCAGGTGTTGCTCACCGAAGCGATGGATCTGTTGACTTGTATCGAATCAAGTTTGCGGGTTGCTGATGTTGATACCCAGATGGCGGTAGCACGGCTTGCAGAGCTTTATTTAGGTGCTGATGATGGTGATCATTTCCCCACGGTCCTGAACAAGATCACCCAGCTAAGAGACCGGATTTATATCCAGGTTGATCAAGCTAATTAAGGGTAGTTAACCCGCCGTGCTCTTTTGGCGGGTATTACTGCTGAAGTGGTAGGTTTTTCCGTGCTCTTTTGGCCGATAAAAAGTTGACAAAACACACACGCTTCGGCAACCGTGTCGGACCATCCCCGCCTGAGCGGGGAGAACGCTGATGAGCCGGGCGCTTGGATTGACATCGATGGACCATCCCCGCCTGAGCGGGGAGAACAAGAGGTGCGTAACCGTCAGCGGGATGAGGAACGGACCATCCCCGCCTGAGCGGGGAGAACACCCCAGACCAGCTGCCTGCAGCCCATGGATCAGGACCATCCCCGCCTGAGCGGGGAGAACGCTGTCAATGAGGTCACGACGATCGCGATTACGGGACCATCCCCGCCTGAGCGGGGAGAACTGGTTGTATTTTTGCTGCGCCTCCAAGAAAGCCGGACCATCCCCGCCTGAGCGGGGAGAACCCGCATCCAAAGCTTCCTGAGCCGAATACCACGGGACCATCCCCGCCTGAGCGGGGAGAACGCGGTAACCCATGAGACGCTCAGGGGCATCCGGGGACCATCCCCGCCTGAGCGGGGAGAACGAGAAGGTGGAGACCATCGAAATCGACGTCACCGGACCATCCCCGCCTGAGCGGGGAGAACGAATCAGCATTGGGTTTTCATGTGGTCGCCAACGGACCATCCCCGCCTGAGCGGGGAGAACGTTTTCCTGTGTTAGCGATGGCACCTCTTCGCCGGACCATCCCCGCCTGAGCGGGGAGAACTAAGCCCGCTGATGATCAAGCAAATACTTGTACGGACCATCCCCGCCTGAGCGGGGAGAACAAGGGGCAGGTGCAATCCCTTGCCGGTGACGCGGGACCATCCCCGCCTGAGCGGGGAGAACTGAGGCCATATTTCAGAGATGTTGTCTTAGATGGGACCATCCCCGCCTGAGCGGGGAGAACTGCCGCAGCGCTAGACACAATGGCATGCGCTACGGACCATCCCCGCCTGAGCGGGGAGAACTTGCTCTTGCGGAGGACATCGTCCAGGTTTGAGGGACCATCCCCGCCTGAGCGGGGAGAACGCTTGAGTGGGATATTGTTACCGGCGCTCTCACGGACCATCCCCGCCTGAGCGGGGAGAACTGAAGCCCCGCTGGTGGGCGGGGCTTGAAGTAGGGACCATCCCCGCCTGAGCGGGGAGAACACACTCATCTCCGCATAGGTGTCCAACCCCCACGGACCATCCCCGCCTGAGCGGGGAGAACACTCAGGCCACCACTCGGGCACTGAATCGGCGGGGACCATCCCCGCCTGAGCGGGGAGAACACTCAGTGTCAAAATCACCAAAACTGCTATTACGGACCATCCCCGCCTGAGCGGGGAGAACGGTGCAACGCTTCAAGAACCGCCGATGATTGAGGGACCATCCCCGCCTGAGCGGGGAGAACACGGCACCCACACCCAGTCGTACCACACGGTCGGGACCATCCCCGCCTGAGCGGGGAGAACTGCTGCACATGGCCCACGGTCGTGGTCGCAGCAGGACCATCCCCGCCTGAGCGGGGAGAACCCCTCCACTGAGAGCGTAGATCCAGTGGAGAGCGGACCATCCCCGCCTGAGCGGGGAGAACTTGCTCTTGCGGAGGACATCGTCCAGGTTTGAGGGACCATCCCCGCCTGAGCGGGGAGAACGGCATCCAGGTGTGCTCCACCCGGTACACCGCGGGACCATCCCCGCCTGAGCGGGGAGAACATGTGCCGCCCACTATTAAAGGTGCAACCAACAGGACCATCCCCGCCTGAGCGGGGAGAACAAAGGGAGATCGCTGATTACTTGTCTGAGCAGCGGACCATCCCCGCCTGAGCGGGGAGAACGCGATTGATAAAACAGGTGATGCTGTAGCTGAAGGACCATCCCCGCCTGAGCGGGGAGAACGAGTCGAACCTCCAAGCTATTGCTTGAGTCGGTTGGACCATCCCCGCCTGAGCGGGGAGAACAGCTAGATCCAAGCACAACTGGTTCCGATATTAGGACCATCCCCGCCTGAGCGGGGAGAACTGAGGAGTCCCGCCGTGGCCGGTAAAAGCGCCGGGACCATCCCCGCCTGAGCGGGGAGAACCCGACTTTAAGCGCAACGAAGCCCTCAACGACGGGACCATCCCCGCCTGAGCGGGGAGAACGGGGAACCACTGGATGGTTCCTGCGGTAGGCGGGGACCATCCCCGCCTGAGCGGGGAGAACTGCAGGGCAAGCGCACCGACGGAGTGCATTGGGGGACCATCCCCGCCTGAGCGGGGAGAACTGAATCCTTACCACGAGGCCATGCAGCAATCGGGGACCATCCCCGCCTGAGCGGGGAGAACCGGAGGGTAAGACGAAAGTGTCTAATATTCTTGGGACCATCCCCGCCTGAGCGGGGAGAACTAAGCAAAAAGATTACGAGCTTTCCCGCTTCGCGGACCATCCCCGCCTGAGCGGGGAGAACGTGGTCAAATCCATTAGTGTCTCCTAAATTGGGGGACCATCCCCGCCTGAGCGGGGAGAACAAGGTGTCGGTATTGAACCACACTCCGCTGGCCGGACCATCCCCGCCTGAGCGGGGAGAACATACCCACTAGCGTTTGCAAGTCTTTACCGTCAGGACCATCCCCGCCTGAGCGGGGAGAACGGCATGGCACAAGAGGATCGACAGGAAGCCGCAGGACCATCCCCGCCTGAGCGGGGAGAACGGGGAACCTGTACCAAATCCGTTTCCACCTGCCGGACCATCCCCGCCTGAGCGGGGAGAACGTGTCACCCGCCTCAAGAACGATGGTGCCGGACGGACCATCCCCGCCTGAGCGGGGAGAACCAGACTGGCCGAATCCAGATCGATGACCTTGGGGGACCATCCCCGCCTGAGCGGGGAGAACGTCAGCGGCTTCCTCAACGTCGGTTGCCAAACCGGGACCATCCCCGCCTGAGCGGGGAGAACTTCTGAGCAGCCTGAACCGCCAACGAACCCTTGGGACCATCCCCGCCTGAGCGGGGAGAACATAATGAGTTACATGAACAACCACAAACAATGGGGACCATCCCCGCCTGAGCGGGGAGAACTCGTCTTATGGGCGTTGGCAGGACACTATGGCGGGACCATCCCCGCCTGAGCGGGGAGAACTCTTCGCCTTGGCGTACCCCTCCTTGTATTCGGGGACCATCCCCGCCTGAGCGGGGAGAACTATTCGGGTTCCCGGTGGTGGAACCCAACCATGGGACCATCCCCGCCTGAGCGGGGAGAACTGCAGGCGCGTTCTGGTTCTGCTGCATGCGCTGGGACCATCCCCGCCTGAGCGGGGAGAACGGCTCGGTGAGCTTCACGCGATCCTGTTTGCGGGGACCATCCCCGCCTGAGCGGGGAGAACATTCGCCATCTTTGGCGTGATCCGGGCGGGCGGGGACCATCCCCGCCTGAGCGGGGAGAACGGAATCCGGTCACTTGGATCCACAAGCAATACCGGACCATCCCCGCCTGAGCGGGGAGAACGGGCCAAAACCGCTAGTCAGCGTGTATGAATCCGGACCATCCCCGCCTGAGCGGGGAGAACTCGTCGGTGACCTTAGCTTTCGCCTTTTCCACCGGACCATCCCCGCCTGAGCGGGGAGAACAGTGACCCACAGCCTGCCGAGCAGGGGGAGCTGGGACCATCCCCGCCTGAGCGGGGAGAACCTGCAGTCAACTCCTCTGCGAACGCCGCTGCCCGGACCATCCCCGCCTGAGCGGGGAGAACAAACTCAGCAAATCTCATCAACGATGACGACAGGGACCATCCCCGCCTGAGCGGGGAGAACCGAGTAATGATCGCGTTGATTAGGACTGGATAGGGACCATCCCCGCCTGAGCGGGGAGAACTTGAGTTGCTTGTCCTTGATGAGTGCTTTGATCGGACCATCCCCGCCTGAGCGGGGAGAACGTTTGGTGCGCGTGCACCTTTTCCACCCATCTGGGACCATCCCCGCCTGAGCGGGGAGAACGTGGTCCAGGGTGACGGTTACGTCCACGGTGACGGACCATCCCCGCCTGAGCGGGGAGAACGCAGCATGTGCGGGGACACAATCAAATCACTCAGGACCATCCCCGCCTGAGCGGGGAGAACCAATCACCTACCTTGAGCCCAGTCGCAAACGCAGGACCATCCCCGCCTGAGCGGGGAGAACTATGCGGTGGCGCACCAGGCACGCACAGGGGCTGGACCATCCCCGCCTGAGCGGGGAGAACGCCAGATCAAATACCGAATCAGGGACGATAAGCTGGACCATCCCCGCCTGAGCGGGGAGAACCTGTTACTGAGACAATCGCTGATCCTGCGCGTCGGACCATCCCCGCCTGAGCGGGGAGAACCTGAGATCAATTCGTTGGTTGCGGATCAAAAGCGGACCATCCCCGCCTGAGCGGGGAGAACGCACGGCCTAGTCCCCTATACGATGACGGCCAGGGACCATCCCCGCCTGAGCGGGGAGAACGACGCGAAACTTCCGCCGTTTTTTGCCCATTCGGGACCATCCCCGCCTGAGCGGGGAGAACGTTCATGGTTTTGCGATTGATTCCATGATCACCGGACCATCCCCGCCTGAGCGGGGAGAACTGAGGGTGCTGGGAATTTGGGTGCTATCAACGCGGACCATCCCCGCCTGAGCGGGGAGAACTGGAGCGTGACAGCACCATCACCCACACCGTCAGGACCATCCCCGCCTGAGCGGGGAGAACGATTCCGCAGAGACCCGCACTAGTGGTGAAATCGGACCATCCCCGCCTGAGCGGGGAGAACAAATCGCGCACCTTCGCACCGGCCATTTTCAGCGGACCATCCCCGCCTGAGCGGGGAGAACATCACGGTGTGGGGGCATTTTTTCATGCCCCACGGACCATCCCCGCCTGAGCGGGGAGAACCTAAATAACCAGGGAAAATATTCGGTCCTTTCGTCATTTTATATCATTTTGCTTTGCGTCGACGAGCAGCACGATGCTGTGAAGCTGTCGACCACCCGGCTTTCATCGAACCTTTTGCTGTCGATATAGGATGTCGCATTAGGGTGACACCTTCGAAGTCAGTCTTCTCCCATTGACTGCGGTGTACGCGGATGTCAAAACCTTGTTCATTGTCGCGAGTCGGAAATGTCATAACTGCTCGTCCATTGGTAAGAGTGGATACGATCATGTCCCATATTTCGTCTCGGACTCTGGCTGTAGGGCGACCTACAAATACGCCAGGGCTTACCTCGATAAGCCAGCGGGTTAGATGCCCGCGTAATTTTTCGGGAGGTGAAGATAATATAACGGTAATCATTTTTCTGACTCCGGAAAATGGACAGGATCCCCATAATTCGTGCCTCCGGAAACGCGTCGATCATTTCCATCCCAAAGCTGGACAATATCGGCCCAAAATTCTTCGGAGGAGACGGTCTCTTCGTCGATAAGCAGGGTTTTTAAGTCTGCCGCCACTCGTTCAGCTAACCGCAACTGTTTAAAAGCGTCGCGCATGGCGCGGCGGGTAATAGAGCTAACATCTGACATTTCGGCACGACCATTTTTGTTCAGGTCGGAAACAACCTGGAACGCGACGGGAATGGAAAGTTCTGCCTTATAAAGGTCCGCGATATCATAAACAAAACTTCTATCGTGGCCGGTGTGTACAAATCCAAGGCCCGGGCTGCAACCCAGCGACACAATTACGGAATGGCAGAGTCCGTACAAGCAGGTATGCGCTGCGGAAAGAGCCTGGTTGATGGGGTCGCCAGAAAGAAAGTCATCCGGATCGTACATGCGACGATTCCAGTCGACGCCGTATTCTTCAGAGTTTTGACGGTAGATTTTTCGGACGCGGGCGCCCTCTTTTCCGCGAAGTTGTTGCATGGTCAATGAGGAGGTGTCCTCATTGGGAAAACGCATGTCATACATTGCGCGTGCGACTGCTAAACGTGAGCGGGTGTTGCTTACTTTTTCAGCTTGTTTAACCAACAATCTGTCTGATCTGGCGATGGAACGTCCGTGGGCATAGTACCGTACTCCCTCTTCGCCGACCCACACAATACTGCATCCGGAATCGGCGACGACAGATACGGCTTGGTGGGTGAGTCGAGTGCCTGGTCCCAGGAGCAGAACGCTGAGAGCCGCGACAGGGACGTGTACTACGCCTTTGTCGTCGGTGGCAGTCAGGGCACCACCGTCTCTACCGAGTGTGCAGTGTTCCAAATACAAAAAGCTTATTCGGTCTGTTGCCCGGCTCAATTGCATTGGTGTTGACGGTGGCATTCCTGATTGCATGATGGTTACTCCATGGGGGCTAGCGTGAGTAGGCCACATCCGTAGCCTCGGGCTTTGCCAATTCCATTGCACAAAACTTCGCGCAGCTTGTTGGCGTCTTTTACTTCGAGGGATCCTTCAAATGTGACTTGCTGAATGGTCACGGTGCGCTTTTCTCGCCTAAATACGCGCCGTTCAGATTTGGTGGTGATGGCGGTGATTTCCCCGGCTTCGCCGGTGAAAGATGCGCCGAGCTGCTCTTCGCGGTCCGTCAGCCAGTCAAGCTGGTGCGCAGGGGTGAGGTGCGCTTTTCGACGCTTGACCCCATCTTCCGTCACTGTATGCACAGGGTTAGCAGTCAGCCGAAAGGCATACTTTTGACCCTTCACAATGCGATTAAGCATCGCGGTGTAATCACTAGATTGCCAAGACTGTTCCTGTGACCAGCCTGCCTGTTCTTGAAGATGCTCAAATGAAGGAATTGCAGGGCTTACCACATACAGAGCTACCGACTCTCGAGTTTGATCGACCCTCCACAGCACTCGCCCTTCATCGGTGGTTTCCGATGAAGAAGGAGGGAAAGATGACAGCACAGCGGCATGCAACTTCTGAGGATTCGCCAAAAGTTCCCTAGTTTGTCGACGCTGCGGATTAAGGTACATCCGTGACATATACATTTAAACACCTCCTATCAGGCTAAACGGATCGTGGTCAATGGGTTTCTTACCCACTTCATTGGAGATGGTCACTGAATCGTGCTTGATCGGTCGAAGCTCGTAACGACGCTCCTTTGGATCAAAACTCTCGGGAAGATCTCGGATTAATTCGTCTGCAGATTCACCAGGGAGCAGGTCCCTAGAAATCGGCAGTCGGACTGAAGTTGAAGCCTTCTTGCGGTACCAGTCTGCGGCGAGCCAGTCGGATTTTTGCAAGGCGATCTCAAGATTCTCATTGACAATCTTCAAAGGGACACGCTCTCCAGGAGGACAACTGCGTCGACCAAGGTAGAGAGGGAATACCGGATTCTTCAGCGCGGTTTCCAGCCCTTCGAGGATTTCTTGCGGACCTTCTATTGCAGCGAGAAAGCGATAATCCTGCAGGTAATAGCGATTAGTTAGGGGTTTAGCTTTGTTGGTTCGCCAGTCAATTTCCGTTTGAAAATCGCGCAGGACACTTCCCACTTGATCAGTGCGGACCCCAAATCGAAGGTTCACCAAATCAGCAACAGACTGTTCGCGGGGGCGTCCTTCTGCCGCAGCAAGCAATCCAATAACACCACTTTTGGTGGGTGAGGACGACGTCGAACGATTAACAAAACGGCCGCTCACGCCCCATGATTGCATCGGCCCAGAAAGCCGGAGGAGCAGGGTTGGCATTAGTTCTCCTGAGTGGAAGTGCGTGCAGCGGCGCCTGCGCGCTTGATGATATCTTCAAAGGAGGTTGCATCCCAGCGATCACCAAAGGTCTTTTCCAGTTCTTCAGAATCGACATTTGTGTTAGCCATTCCAAAGGAATCGACGGGCTTGGTGCCGTATGCAGCATCGCCATTTACTGCGTACTCAGCAAGCTTAGCGGCAGCAAGAGAGACAGCCTTGCCTTCATTCCGGACAGGATTCTCAAACGCGTTTACCAAGCTAACTGGCTGGTCATTGCGTACCTCGACGTAAACAAAATCAGGGCGGGTGCGGTTAGCAAAAGTGTTTTGCTTACCGGTCGGCATGGACACGGTGAAAGAACGGACAAAAGCTTCAATTGCACGCGCGGCCGCATCAGCGTCCCCAACGTTTTCCACAAGCTTGTCAACGTTGACTGTGGCATAGCGGTATAGCGCGGACGAGACGAATTCCTGGGTGCCGATCATACCTGCGCCCGCATTGTCTTCATCCGCGTTGTCGTCAACAGCGGTGTAGTAATCAAATTCACGGGTTGCCTTGTGCACAGACAATGCGTGCTCTACCTGGCAAGATGCATCCACATTCGCTTCAGGTGCATCCGCAAGCATGCGACCGAAAAGTGCAACATCAATAGCTTGGGGTCCCTGAAGAGCCTCACGAGCCTGCTTTTTAGTTGGCTTGTTGCCCTCTACCTGAGCAATAGCCAGTTCGGCGAGAGCATCAATTTCTGCACGAGAAAGGAAAAGGAGGTAGCCCGTCTTTGTAGGCAGAGTTTCATCCTTCTTCTTTTTCTCCAGGGCGATTCCAGCAGTCTTCAAAATTTCTTCAGCTGCTGCTTCTGCCTGCTCTGCGGACAGTTCTTCCTTGAGCTCCTGGATGCGTTGAGATACGCGCTTTACCGCCTGCAGTGTGCGTTCGCCCAGTTCAGAGGAATCAAGGTAATCCTTGAAATCATTGCGAACTGCGCGCTTCCACGCCTGGCTGGATACGCGATGGCGTTCCACACCACCAAAGATCGCCGACTTCGGAGAGCCAGTATCATCACGATTGATGCATGAAGGAGGAACAAGCTGCACGAGGTGAATATCAACAAAGGTAGACATGAATTATCCTTTCAGGATTTAAGATTCTGAAGCTTTTTCGGTAGTTTTTGGTGCGGTATACAGCTGTCGACCCCATGCCAAGCGCACACGATCGCGCGCTTCCGGAATATGGAAGTCATAGAGCTGACCAGCTAACTCCGCGAAATCGAGTTTTACATTAGATGCACGGAGCTGAGTAATGGTGTTGCGAAGGTGCCACAACAACTCATCGACGGAATCGGAAGTAGATAGTGCATTGAAGCGCCTAAGAATCGGGGATTCATTATCGAATCCACCGCCAGGATCTTTGGTAAGAATGTACTGGCGCACAGCACGACCCAAACCCTCGCCACGTTGGTTCATCGAATCACCCTTGCCCTGCTGGTGTAGAGCAAAAAGGGCCAAAGCGTTGTGAACTGAAGTTTCTCCCCAACTAGGTGCATCAGTTTTACCTACTAGTTGTTCTGGAAGATCTTCTAGGGTGATGCCCCAAACATCAGGAATTGCTCCCGGTGCTTTACCCACCGCACGTCGTAGCTTGGCTAAATCTGCTTTTGACCTTGATGTGCCAGCAGACAGATGGGCTTCTAGCTCATGTAGCTTCTTAGCAACATGAGAAACTACGGCACTTCGATTAGAAACTGAAGTTTTTTCACTCATCTTCTACTCCTTTCTTTGAATTAAGGTTCTCTCCGAGAATTTTGTTGAGTGAACCTTGAAGGCGGTTAAGTGCTACGGGCCCTGTGATTCTGTTTGAATCTTTCATTCGTCCAGACCAAACGCTTGGTGGCTGTTTGGAAAGGATTTGTTCTGCCTGAGCTCTCGCAGTTTGTCGAAGCTGAGCATCCCATTCAACGAGTAGCGCGTCAGGGTCTTTAGATTCGGAAAGCTTGGTTAGCCATTCTCTGAAAGGACCATCAATTGAGAAAAAGAATTCGCGCTGTACTTCATCGGTATCCGAAGCCGTATCGCCTGAAACCGCGAAAGCAATGTTGGAGTTGTATTGGCGAACGGCATAGTCCACTTGCTCAGTCCGCTCGATTGCAAGACGAGCGATGGATCGCAGAACTTCTCCATCTGGAGAAAGAAGCAACGCAGAAAGGTGTACAGAGTCCGACAAAATATCGGCATAGCTGGAGCTTTGGGCCCCATATTCCATTGACACCATGCGCATGCGAATAGGGAACGTGGGATCCAAATATCCTTGGGCTGAGAGCTGGCCGACCCACTCGACAGTTTTGGCAGGTTTCGATTGTGGTGCGTTGTCAGAGTACTTAGTCTGGGCCTTTGCAAAATTTTGATTCGGCAGAAGATTAGGAAGTGTTCTCCACATTGCTCGGCCCGGCTGGACTGATGCAGGCATATACCTCAAACGTTTAGCCTTGGTTGTTTGAGGATCACTAAAACGCCAAGGCGACATAGTTTCGACCTGGTCCTGGACCGTGTAGCCAAGAGCGTCCCCATTAGAAATAAGTACGCCAGTTACCTGGTCGTTTTCCCATTTCAATCGAAGCCTGCGCTGAGGCCAAGTGAGTAATTCCACTGGACCTGCCGCTTTGGCGATCAATGCGTTGTCTTCAAAACCAGGTCTAGCAGAGCTTGTGAGAGGATCTTCTAATTCCCACACTGGAACATCTTCGTCCGATCCAGCTTGCTCACGCTGTGGAACATAATTGAGCAGCAGCGTTTCAAGAAGATTGTGGCCTTCCAGCGTTGTGCCACCAAGCCAGCCGGCCCAACCGATACCGATTGGATAGCCACGGCCCCCTTTAACACGATCATCGCCAACTGCTCCCGACTTGATGCCTGAGTAATCGAAAGCATTCGTATGAATAAGAAATGCGGCGGCGCTTGCAGGAGATAACGATGCAATATCAGTGCGCATGGTGAAAAGATCACCAACCTCACCCGCATCTGGGATGAGAATATCGAGAGATTTCCACTCATTCTTCGAAGTATGCAAGTCTGCAACCTGCATGAATGGACGTTCCGGATGACGAAGATCAAAGCGATCCTCGAGTTCATCTAGGTAGTCTTCGACTTCACTATCAAAAACTGATCGTGAAACCCATTTCTGTTGCCAGTGCTTTGACGCAGCCATTTGATTGCGCCATTGAGGGCTGTCCCACGAACGATAAAGTATTGCTAGGAGAACTCGAAGGATTGCGAAGTTCACGGTCTCGAGAGAAGCAGCTAATCGTTGGTAGTGTTCAGCATTTTCTAGAAGTTCTTTGATGGAAACTGTGTCAGGGGAGCCATCAATTCGCAGTACTTCAATCCATGGTTCATCTAACAAATTAAATACGGTATTGTCACTCATTTCTTCCTCCTTTCGAGAAATTACTGTTGTTCTTTTCGTTCTAAGAGCAGGCCTAGTTGCTCGTCGTATCTAAGGATGTACTGCTCCAGCGCTCTCTCAAGATTTTCATCAAGAACTAGAGGGAGTGATCCCTTAAGCCAACGTGACTTTTGCCAGGATTCCTGCCCGTCCGCTTCCAAATCAAACAAGTCGTCATCAGTTAACGACCACTCTGGAAGGCGAACCGTGCACGTAGCGAGGGTTCTTGCAGTTCGGTATTCAAGTTCCATCACTCCGTCCACTGATTGACCTTCCAGGTCTTTGATATGTGGCAGGGCAAATAATCTGCCCATCCTGTTTTGCACTACGACGACTTCGAAAGATTCATCGGCATCGCGTACCTGAGCGACAGCAGCTTGCTCATCAGCGAGCGATGGACTCTTGGTCCATTCAGCCAATTTCCCAGCCAATGGATCTGGAATCCGTGCAGTCTCTGCGCGGCTTTCTTGATCGGTTTCAAATTTTCTTTCCTCCACGTGAGCTGCAGTCCAAGCATCTTTCCATGCTTCTGGAGCAGTCTTTTTAGTGTCATATGAAGACGTCACCAGGCTTTCTACATCATCTGGGGTAGTGATTGTTCCATCTGTATTTGTCGCATGATCTGCTAAAACACGGATTGAACGCAACAGTGGGGCATGGCGATAAACTCTTTTGCTACCGGTTTGAATTTCTGGCGCCGACGCTTCGATATCGGGCAGACCTGTGCCAAAAATCTTCAACTGCGGAACCTTAAGAGAATCTGGTCGTGAATCATTGAGCATTTGATGGCGGTGCACGCGGCCGATTCTCTGAATGATGAGATCTGTCGGCGCGATATCAGTGATCATGGCATCGAAATCTAGATCGAGGCCCTGCTCAATGATTTGAGTTGAAACCACAATCAGTTTCTTTGGTCGCGAGGCACCAGCTTTGCGGCCAAGTTTCTTTACTAAAGCCGACTCGAGAATCGCACGATCTGAAGTAAGGAATCTCGAATGGAGGAGAACCACTTCTTCCTCACGGGAAGAAACCAATTTATAAAGCTCTTGGGCACGAGAGACTGTGGAACAGATAATGCCGATGCATCCGCCATCCACCGACAGCTTTAAAGCCTCATCGGCCATCTCTTCCAAATCGCCTTCCAGAAAGGAGTAATGAGTTGTTCGAGTAAGACCATCGTGCTCAGGTGTGATGGTTCCTGACTTCTCACCATCGACCCAAGTTATACGTGGATACACTGGGGCTTTGTCGATGCGGGCCTTGCGCCCGCTATACCTAGACGCGCCCTGCTGGTAGGCGTCGATAAGCTGCTTTCTGGTTTTTGGAGGAAGCGTAGCGGACAAAGCAATGACTGGGACACCGTAAAGCCCAAGCCATTCAAGAAGACGAGTGGTGTATACCCGCATGTAAGCATCCGCAGCATGGATCTCATCGATGATAACTACCTTGCTGGCGAGACCGAGATGGCGAAGTACGTTGTGCTTGGACTGCAACACCGCGAAAAGAACTTGGTCAATTGTTCCAACTGCTACAGAAGCGAGAAGTCCAGTTTTGCGGCCCCGGAACCACTGGGTGGCTTCCAGAGGTGAGTCGCCGTTAGATGAATCGTCGTCATAAATAGCTGTTAGATCACCAGTCGTAATTGCCTTAAAATCGTCATTGAACTCGGCTTTTCCATGAGCAAGAACTGTCGAAATGGTGTCTTCGGGGACGGAGTGAATAAGCCATTCCGCGACACGGGTGAAAATGGCATCCGAAGTGACTCGGGTTGGCTGCGCGAAGAACAGTCCGGTAAACCCAAACTTCTCTGCCATGATCTCTGCCAGAGCTAAAGCTGCTTCTGTTTTTCCGGAACCGGTCTCATTTTCCAAAATCACCAAGGCAGGTTTATCCAGTTGATGTCCAAGCTCGACCACTGCTTCCTGCACATTACGCATCGTTGCTGATGCAGGAAGAGAGAAGCGGTCAAGGAAACTTTCAGTCGTTACCTCTCCTGGTTGCCAATGATTGCCTAGATTGATTCGTGTTAAAGCATCTTCGGTGCGGTAATCCTGATCCTGCGGTTCACCGTTTGTCAGCGGAAAGTTATCAGAAGAAGAAGCAACCCAGTCAGCGGAGATAAGAAGACCAGTGATTAATGCTGCAGCGGAAGTCGACAACATGTTGTTTTCCATGCGGTCGCCAAAAATTGAAGCGAGTCCATGCAAAGACTCTTCGTCTAAATCATGTTCAGAAGTGAGTTTGTCGAGCAGTGCGAAGCGAGCTTCTTGCCACTCTGGCCAAATTCGAATCTCTCGCAATAGTGCATCGGAAGGTAAGGAAAACTCACTATATGAGCCGTGGTGGCCCGCAATTACATGGAACCAAAACTCGCGGTCCGGTGGGCTTAATTTGAATCCACGATGCTGTTCAAACCATGCAATCAGCGTATGCGCACTAATGATGGAGTGAGGATTGGCATAAATTTCTTTTGAGGTTACGTCTGATCCATAGCCCTGGTGGGTTACTCTCTGAGATAGTGAAGGCACTTTTTGCTGAAAATATGGCGATGCTTTGCCGACGTCGTGTGAAATTGCGGCCAGAGTTAAAATCTCATGCAGGGGAGTTTCGCCAAGGATGGATTGCAAAAACTCCTCAGAAGCGGGGGCGAGGAGCTTTTTGGAAACCTCGTTAATCACCGAGGTGATGTCGCGGGAGTGCTGTAAAAGTGACATGTGCTCTGAAGTTTTTTCTACAAATTTTGCCCAAAAGACTTCAAGATCGATCACTATTTGCATCCTTCAATTAGAAAAATAAACACTAGACGTCCAAAGATTTACTCTGATCCTATCGCCAGAATGAAGCCGATGTAAGAGATTGTCGCTTTTGGGGTGGACATTAGGGGTAGAAAATATTCTAAGTGCATGGTGAGAAGTTTTCTTTTATACAGATAAACACCCCGATTTGAGCGAAAATAATTCGAACAAATGGGGGTGTTTACTGAGTTAATCCCCACTTGCGTGGGGAGGATGATTACCTAGGACGTCTAGTGGGATCATCCCGTTTTGAGGGACAGACAAGAAGCGAGTAATCGTTCAGTCAAACCTAGGTCTTATTCAATTTACTGTATATACAATCTGAGTTACAGGGGCAGTGTAAATCTAAGCCATGCAACAAGAATTATGGGGTTGAAACTTTACCTCGGATGACTAGTATTAAGGATATAAGTCACCGACCCCCTCTGAACCCGACCTAACCGTCAAGTAAGGGGTCGGTTTTCCATATCTGTACTCAGATGATGAGGGAACCAGCTGAATTGAAGCCTTTTAAAGAGCATGATGAGCTGTTGCAAATGCTTGAGGAAAATGGGCTTAAGATTCCAAGTAGTGAAATCGCCAAGAAAGAGCTGAGAAGACACGGCTATCACCGCTTGAGTGGTTACCGTTATCTTTTTCGTGAAATGCTTCCCTTTGAGCAACAGAATTCTGAAACACGTACTTTCAGGTCTAAACAGCATTTAGCGGGATCTAGCTTTGAAGACGTGATCGCTTTGGCAGAGTTCGATTCGCGTTTGAGGTTGAGCATAGTCGAGGCTTTGGCAGATTTCGAAGTACGTTTGCGGACTGCAGTTGCACACACTTTAGCCGCAAAGGATGAACTAGCACATCTCAAAGTAGACAAGTTAGACAGACGGAGCTGCTTGAATACTGCAAAAGGAAAAAGAGAAACCAACCACGAAGTTTTCTGTAAAGAAGTGGCTAGAGTTACCGCGATGGCCATCAGAAGTGATGATTTTGCCAAGCATCATGATGAAACCTATGGTTCAGATCTTCCAGTATGGGCAGTCGTTGAACATTTAACATTTGGAAGCCTTCATTATCTGTTTGGCTTCATGAAAAATGAGGACAAACGAACCGTAGCCAATGCGTTCGGCTTGAGGCATCCGAAAGCACTTGAGAAATGGTTGTATGCACTAGTCGACCTTAGAAATCTAAGTAATCACAGCGCACGGCTTTTTAATCGATCTTTAAAGCGAAGTATTGTGATACCACCTCATACCGTCTCACCTGGCGGCCTTCTAAAACAGACCGAAGAGTTCCTCGACCGTAACAAGCAAGAGAAAGACCGTCTTTATGCTGTGGTTGCAGTTCTTGCCTACCTACTTAAGAGTCATGAATTTGGGAGTGAGTGGCCCACGAAGTTTCGGGAAGTGATGCTTACTTTTCCTTATATTGAATTGGCGGAGTTCGAGGATCCGTTGGTTTCACCGCAAAAAAACATGGGATTTCCTGAACACTGGCAAGGCGATGAATTGTGGCTTCCCTAGCATCAAACAACGCAAAAGCGACGCCGGAACTTAGCATTCCAACGCCGCTTCAGCTCAATACAACAAACTAAACCTAAACCGCCTCTACCTCAGCAAACGAAGCAGTATCAATGACAACGCGGAACTGAACGTCGCCGGCAACAACGCGGTCGTAGGCTGCATCAACATCGTTGACGCCGACAGTTTCGATCATCGCACCGAGGCCGTGTTTTGCACAGAAGTCGAGCATTTCCTGGGTTTCAGGGATGCCGCCAATGTTGGATCCGGTGAGGACTTTTCCGCCGCCGATGAGCGCACCGAAGCTCAGTGGCTGCTTCTCTGGTGGCAGACCGACAACAGCCATGACACCGTGTGGCTTGAGAAGGCTCAGGTACTTGTCGACTGGGATGGATGCGCTAATGGTGTTGAGGATGAAGTCGAATTCACCGGCGTGTTCGGTGAAGAAATCCTCATCAGAAGTCGCAAGCGTGCGAGCTGCGCCGAGTTCCTTGGCAAGTTCAGCCTTGCGCAGGGAACGGGACAGAACGGTAACGTCAGCGCCCTTGGCTGCGGCGATTTGGACACCCATGTGGCCGAGTCCGCCGAGGCCCATGACTGCTACTTTGTCGCCTTCTTTAACGTTCCAGCGGGCGATCGGGGAGTAGGTGGTGATGCCTGCGCACAGCAGTGGTGCTGCGACATCGAAGTCGAGTTCCTCTGGGATGCTGCAGAGGAAACGTTCGTTGACCACTACCTTTTCGGCGTAGCCACCTTGCGTGATGGTGCCGTCGACGTCGTCGGAGTTGTAGGTTCCGACGTTTCCGCGAAGGCAGTTGTTTTCAAATCCCGCGACACACTGTTCGCATTCGCCGCAGGAGTTAACGAGGCAGCCGACGCCAACGCGGTCGCCGACTTTCCACTTGGTTACATCGGAGCCAACCGCAGAGACAACGCCTGCGATTTCGTGGCCGACGGTGAGCGGGAAGTGTGCCTCGCCCCATTCGTTGCGGATGGTGTGGATATCGCTGTGGCAGATGCCGGCAGCTTTGATGTCGATAACTACGTCGTCAGCGCGAGGCTCACGACGCTCAATGATTTTGACCTCGAAAGGTGCTTCGGGGCCGGTTTTCTGGAGTGCTTTTACTTGGATGCTCATTTCCTCGATATTACCTACAGGTACTTTTTGCGGATAGGTCCAAATGCTTTTTGCAGGTTAATAGTGATTGCAGGGAGCGATTATTTTGGAAGGGAACTGTCATTTAAGAGTCTCTATTGAAGTTTCGGGTGCTGTAAAAGCGAGTCTTCGTGGTTCAATGGCTTGAAATTGAGTTGCGTGTGAATGTTGGCTCTGCGAAGCCTGGGGCATTCAGTAACGCGTGCCGATTTATGAAGAATTTATTTACCTTGTGGCTTTTTCTGTAGATCGGCACGCTTGGTAAATACAACTCCAAAAGTGCCCAAAAATGAATCTCTAGAAGTGAGTTTAAAGCACAAAGGGACTCCCGAGGTGGAAGTCCTTTTGTCAAAGTAGAGGCCTTAAATCGTGCTTAAAGCTTAACGGGTGTTTTAATGTGCACTCCAAATTCATAAGCACAGATTCCGGCAATGGCGGTTGCAGCTGCATCAGCAATGATCTTGCCTTTTCCGGCAGTCGCTCCGACAGCATCGGCGAGAGCTCCATGACTAGGGATATCACTAGTTTGTAGTGGGACCCGAAGGTATGGAGGAACAGTGAAAGCTTCTTTAGCGGGTAACTTATCTGAATGCACTAGCTCAGGAGCGAGGTGCATGAGTAAGGAAGTTTCTGTGACCGCGGCATGTTCTAGATCCCAGCCTGGAAACGTGATGTCGGAAAAAACTTCATCCATAACTGAATCTTTAAGAGGATCCCACCAGTTAGCCAAAACAATCTGGTTGTCGGTGCCGTGTTGGCGTTGAGCAAGGTGCATAGCTTCAAGGATTGGAGCTTGGTTCTCGAAGTGCGCACTGAGGAACAAGATCTTGCGGAAACCATCGGCAAGGAGTTCGTCTAGTAGGTTGCTTGCTAATTCCACCATGGTGTTGAGGGAGAGATCTACTGTGCCGGGGAAGAGCGGACCGCCACCACTATAAGGAGAAGACCGGTATCCATAATTGAGCGTTGGAAGCACTATGCCATCGATTTGCTCAGCGACCATTCGAGAAATCTCGGTTGCGATGATGGAATCGGTGGAAAGTGGAAGGTGAGAGCCATGCTGTTCACATGATCCAGCAGGAATGATGGCTACTCCATCAGTTTTGGCAGCGTATTGCTCCCAGCTCATATTGGCTGCAAATATCATTGTGTTGAGCTTTCTATTTGGACTTTGCGGCGAATGTGACACCAATTGCGGTAATGATTGCAGCTGCGACCATGTAGTAGGCCGGTGCAATTACGTTGCCACTGGCACCGATCATCCAGGTTGCGATCATCGCTGCGGTGCCGCCAAAGAAGGCATTCGCGCAGTTGAAAGTAAGGGCAAAGCCGGTGAGTCGAACATCAGGTGGGAATTGTTCGGAGATGAAGGACGGGAGCACTCCGTCGTTAAGCGCAAGGAAGGCACCCATTCCGACCTGGATCAAAATGATTCCGGCGAAGCTTGCGCTGTCTAGCGCGAGGAAAGCAGGAATTGAAAATACTGCAAAAAGTGCTGCGGCCATAAGCATTGTGGTGCGGCGGCCTAGGCGGTCAGAGAGTGCGCCGGTTGCGACGACGAGGACTGCATAAACTGCGGAGGAGATGGTGGTAGCGATAAAAGCACTGCTAGAGCTCATGCCGAGTTCTTCGGAAAGATAAGTAGGTAGGTAGGCCAGAACCATGTAGAAACCGATGGCATTGAGGATGGCGCCGGAGAAAGCTACAAGAAGTGCACGTGGGTATTTGAAAACCTCGAGGATTGGAAGCTTTTTAGCGGAGTCTTCGTCTGCTACGTGAGTTTCGGGGGCCATGCGGCGGATGATGAGGCCAACAATTCCTAGAGGTGCTGCCAAAAGGAATGGTAGACGCCAACCCCAGGAAGCGAGGGAAGCATCGTCAAGGAGGGAAGTGAGAAGAGCGGCGAAGAGAGAACCAAGGAGGAGTCCACAAGCGGTCGCTGCGGGAACTACTGAGGCGAAAAGTCCACGACGGTTCTGTGGGGCAGATTCTGAGATATAGGTAGCTGCTGCGGCATATTCGCCGGAAGCACTAAATCCCTGGATAAGGCGTAGTACCAAAAGCAAGATTGGTGCGACAATACCGATGGAGTTGTACCCGGGAAGTAATGCAATACAGAAAGTGGCAAGGCTCATAAAGAGGATTGACGCGGAAAGGCTCTTGGTGCGGCCAAGGCGGTCTCCGATGTGTCCCCAGGCAACTGCGCCGATAGGACGAATGAGGAATGAGAGTGCAAATAGGGCGAAAGTGTTAACAAGTGCTGCACGTCCGGTGAGCTCCGGGAAGAAAACTCCCGCGATGATGGATGCCATGTACATATATGCGGCGTAGTCGAACCATTCAACAAAAGTTCCAATGAAGCTTGCACGTACTGCATTCTTAAGGTCTTTTTTGCTGATTTCAGAGGTGCTGATTGTGTTGCTAATTGTGGTGTCTGGCGTGGCACTTACTATTGCCGGGTTTTGAACAGACATTGCAGTTCTCCTTTCATTGGCTCACCCCGTCCAATATGTTTCTATAGGGTGATAGAAAAGAATGTAAATACAAGTTTTGAGCAATGTCAATTTCTATAGACCGATAGGTTTCATTGGTGGTGAGTATCACTAATTTCACCCCAATTCCTTTCGGAGAACTCTCGGAAATGGGGATGGTCACGCTCCTGGGCGCTTCTATGTCGGGGCCTTTGTGGATCGGCACCGCTAAGTGACTTGAAATGGAGTGCAGGATAAGAGTTTTAGCCCTGCAAAGACGGGGTGTTCGGTCCAATGTGCCAATTCACCCGAAAATTTCCCTTTCGGCCCCTACTTACGTAAATCGGCACGCTTAGTGAATCAAACTCCACAACCGCCATAAAATGGCTCTTTAGAAGCGTATTTAAGGTAAGAAAAATGGACTCCCGAGGTGGAAGTCCATATGTCAAACTTGAGGCGTTAAAAAGCGCTGACTAAGAAAAAGCTATTCTCCCGCGACGCGCATCAGGTAGTTGCCGTAGCCGGATTTCTTTAATTCCTCACCTAATACCACTAATTCAGAGCTTGTGATGAAACCCTCGCGGTATGCAGCAACTTCAGGGGAACCAATGATATTGCCGGTTCGTTTTTGTAGCACCTCTACATAAGAGGAAGCTTCGGACATGGAATCGATCGTGCCGGTGTCCAGCCAGACGTCGCCTCGGTCTAGGCGCTGCACAGTTAAAGCACCTTGCTGGAGGTAGGCATCGTTAACGGAGGTGATTTCCAGTTCGCCACGCGAGGAAGGCTTGATTGACTTGGCGATGTCCACCACGCGGTTGTCGTAGAAATATAGTCCTACCACGGCAAAGTTGGATTTTGGCGCGGTGGGCTTTTCTTCAATAGACACCGCCTTATTAGCAGCATCAAATTCCACCACGCCATAACGCTCAGGATCGGAGACCTCATAAGCAAAGACAATGCCACCGTCGGGGCTGGAGCACTGCTTTAGTGCGCGGCCAAGTTGTGCGCCGTCGAAAATGTTGTCGCCAAGCACCAACGCGACGTCGTCGTCACCGATGAATTCCTCGCCGATGATGAATGCTTGGGCTAGTCCGTCGGGGGAGGGTTGGACAGCGTAGGTGAGGTTGATGCCCCAGGAGGAGCCGTCGCCAAGCAAGCGTTCAAAGGAGGCGCTGTCTTCGGGGGTGGTGATAATCAGGATGTCTTTGATGCCGGCCTGAATGAGCGTGGTCAGTGGATAGTAGACCATGGGCTTGTCATAGATCGGCATGAGTTGCTTGGAGATGCCCTTGGTGATGGGGTAGAGCCGGGTGCCGGAGCCGCCTGCGAGGATGATGCCTTTCATTTACAGCTCCTTGAGGTAGTTGTTGAGGCGGGTCTGCCAGGTGGGTGCGCTAAATCCTGTTGCTTCGATCTTGCCGAGTTTCAGCACAGAATTCAGTGGGCGGGGCGCTGCGTCTTTGTCGGCGAAGTACTCCGCGGTGCTCACGCCGGTGACCTTGCTGGGGTCAGAGAACACTGCGCGGGCTATATCGGCCCAGCTTGCGGGTTCGCCGGTGTTGGTGAGGTTGTAGGTGCCATATGCTGCGCCAACATTCAAAAGGTGCGCGATGCCGGCTGCGATGTCTTCGGTGAAGGATAGGCGGCCGATTTGGTCGTCGACAACCGAAGGTGCGATGCCGCGTTCATCGAGTGATTTCATGGTGCGGACGAAGTTGTTGCCGTCGCCAATCACCCAGCTGGTGCGCACAATGTAGTGGCGCGGAGCGGTGGTGGCTGCGATGTCGCCGGCTGCTTTGGATTGGCCGTACACGCCGAGTGGGGAGAACGGTGCGTTTTCATCGTAGGATTCGGCGGTGCCATCGAAGACATAATCTGAGGACACGTGCACGAGGGTGAGGTTGTTGTCGCGGGCAATGGTCGCGAGGTTGGCCACTGCCGCTGCGTTGATGTCCCACGCTGCTGCGCGGTCGTGTTCTGCCTGATCAACGGCAGTGTAGGCGGCGGCGTTGATGATGGTGGAGTACTGCTTCCACGCGCGAGCTTCGGTGAGATCTGAGGTGATATCGAGTTCCTCGCGCGTGACAAATTCCGCGTCTGGGAACTGCGCGCGTAGCGCGGTTCCCAGTTGTCCGCCGGCGCCGACCACTAGAACCTGGCGGGCGGGCAGGGGGGTGGCGTCGATAAGCGCTGGATGTTTTTTATCTTTTTCGGAGATCTCGGTGATCGGCAGCGGCCAGTCGATCATGTTGAGGTTGACGTTGGCGTAATGCGCGTCGGGGGACCAATGATCGTTGACGAGGTAGGTGTACAGCGTGCCGTCCTCGAGAGCCTGGAAGCCATTTGCCACACCACGCGGGACGTAAACTCCCACGTCAGGGGTAATTTTTTGCGTTACGACGTTACCGTACGTGCTCGAGCCTTCGCGCAGATCCACCCAAGCTCCGAAAACGGAACCCACCGCGACGGACACAAATTTATCCCACGGCTCAGCGTGCATACCGCGAGTCGTGCCGGCGGTGGCGTTGAAACTCATGTTGTTTTGGACGGGGCCAAAATCGGGCAGCCCCAGGCTGGTCATTTTGGTGCGCTGCCAGTTTTCTTTGAACCAGCCGCGGTTGTCGCCGTGGACGGGGAAATCGAAAACCAGCAGGCCTTCGATGTCGGTGTCGCGCGAGGTGAGTTCTTTGTTAAACATTATTGGCCTTGCTTTGCGTAGGTTGCTTCGACGTTGTCCTTGGTGCCGCGCCACCAGGCCTCGTTATCGCGGTACCAATCGATGGTCTGCTCTAGGCCTTTTCGCATGCCGGAATCAACGTCGGTGTATTTCGGTGCCCAGCCGAGCTCGGTGCGCAGCTTGGTGGAATCCATGGCGTAACGCATATCGTGGCCGGGGCGGTCTGCGACGTGTTCGTAGGCGTTTTTGTCGAGGCCCATGAGTTCGCAGATAAGCTCGATGACCTGCTTGTTATTCACATGATCGTTGTCGGCGCCGATGATGTAGGTTTCGCCGATCTTGCCCTTGCTAAGGATGAGATGGACGGCGTCATTGTGATCATCGACGTGGATCCAGTCGCGGACCTGCTCGCCGGTTCCATAAAGCTTAGGAGTCAGGCCTGCCAGGATGTTGGTGATTTGGCGGGGGATGAACTTCTCAATGTGCTGGTAGGGGCCGTAATTGTTGGAGCAGTTAGACATGGTTGCCTGGATTCCGAAAGAACGGATCCATGCGTGTACCAAGTGATCAGACCCGGCCTTGGTTGCAGAATATGGAGACGATGGTTTGTAGGCGGTGGTTTCAGTGAAGCGGTTTGGATCATCGAGTTCGAGGTCGCCGAAGACTTCATCGGTGGAGATGTGGTGGAAGCGTTTGTTGTGCTTGCGAACTGCTTCTAGCAGGACGAATGTGCCGATGAGGTTGGTGTGGACGAAGGGGGAGGGATCGTTGAGGGAGTTGTCGTTGTGGGATTCTGCTGCGAAGTGGACGGTGATGTCGTGGTCTTTGACGAGGGTGTCTACTAGTTCGGCGTCGCAGATATCGCCTTCGATGAGGGCTACTTTGCTGTCGGGGAGGCCTTTGAGGTTGTCGGCGTTTCCTGCGTAGGTGAGCTTATCCAGCACCGTGATGTGGGTGTATTCAGGGTGCTGCTCTACGGTTTGGCGGACGAAGTTGGCGCCGATAAATCCGGCACCTCCGGTCACAAGCAAAGAAGTCATGCCGTCTACCTTAGTTCGTCTGGGCGAGCTGGCAGAGTTAGTAGCTGTTGTCGATGCGCCTATTCTGCAAACGGCCAGGGTGTTCCGGCTGTTCATTAGGGAAACCGGCTGCAATAACCAGGGCGATTGCCCGATCGTCACGCCCACCAATGCCGATTGCTTCCTTCACTTTTTCCTCATCCCAACCAGTGGTTGGGCTGGTGCTCAAACCCTCCGCCTGGGCAGCCAAAATTAGGAAAGCCGCCGCGAGGCTGGCATCCCTCAACGTTGCTTCGCGTGCCTGCTGAATGCTGCGACCATTGATGAAACCCGCGACACGTTCAGCCCTTTCTGCACCAAGAATCTCTTCCAAATCCTCAGGCTCGTTTTCCACGCGGGCAACCGTAATGAAAGTTACAGGTGCGGTGAGGAATTGTTTCTGATTGGAGGCCTCGTAAAGCTTCTGCTTCTGTGCGGGATCAGTAATCACAACAATTTCACGTTGCTGCGCATTGAACGCGCTGGGTGCCTCCAGGGCAAGGTCAACGATTTTGTCGATCAGCTCAGGGGTAGGAGCTTCATCGGTGTATTTGCGGGTGGCGCGGCGGTTGGTAATCGCCTCGACGACTGAAAGTGACATTTTTTATCCTTTTTATGTGTTGGAAACAGAGTCATGGTAGGTCGCCTTATTTGTCAGTGCAAGGGTTTTATTAGCTTTTGGAGATAGTTTCTGGCTGGTTGGAATAGTTGACATCTGTGCAGGTTGGGGGCTTTTGTTTCCTACTTGGGGTTATGTGAAGTGGGGTGCTGTGTGGTGTTTTAAGCGGTCGACTGTCTGCGGCGACCTGTTGTCCTAGTTTTGGCGAGTTGGGCGCTTAGAAGCGGTTCTAGAGGGGGTCGAATTTGTGACGATTGGGGCTATTTTGATTTCTGCTGGGTTGCTGTGGGCTTGCTGATCAACTTCTCGTTCCGACGGGGCCTCGCTCCCTCAAACGGGGACGAGTTTTCGCATAATACCCCGTGATTAGCGCAAATTTTCGATTAAAATGGCCTTTTCCCTCTGGCTGGGGACGGATTTTCGCAACTTCAGGCAGTCACGTGTTGGGTGGGGTGTGGGTGGACCCATGTAGGCGGCGCCTACTGGGTGATGATGGTTAGGATTCTCCATTTTTAGGATGCCACCTCGAAAAATGGTGAATCGGCACGATTTTAACCCCTCGAAAGTGTGCCAATTCAACATATTCTGCGCCCAACCTTCAAAAAATGGTGAATCCTAACAGGCTTAGGGGGCTTGCAAGGCGGGACTCATGCCGGGGGTATGCCTTGGGGCGCGTATTAAGGATAACCTTGCCTTAATTATTTGGATTGCAGTAATTTAAGTGAATGCATTTTTGTCTCCTGTCTCTGGCCAGACCTGCCAAAGTTGTGGCCCCACTCCTCGGCGCCGCACTGCTTCTAAGCTCCTGCTCTTCAACATCTTCCGATGAACCAATCCAACCTGAAGTTGCCAGCACTGGATATTCAGTGGAACACGCAATGGGCACCACCGAAATCCCTGAAACTCCAAAGCGAGTAGTCGTCATTGATTCCCCACACCTCGACGCACTTTTGGCTTTGGGAATTACTCCAGTCGGAGCTACGGAATCTGGATCCGAAAATGGATTCCCCGCCTACTTGGCTGACGAGCTAAAAGACACCGAATCTGTTGGGCTGACATCTGAGCCAAATTTGGAAAAGATCACCGCACTGGATCCGGATTTGATCATTGGCGCTAAGGTCCGCCACGAGGCTATTTATGATCAGCTTTCAGACATCGCACCAACCGTGATGTCCGAAGGTTCCGGCACAAACTGGAATGAACAGGCAGAAATCACTGCGGCAGCAGTAAACAAGTCTGATGAGATGGACAAACTGGTCTCAGACTTGGACACCCGTGCCACAGAGCTTGGTGAAGAGATTGGTGCTGACGGACAAACCGCTTCAATGGTTCGATTCCGCACGGACAACTTCAGGCTCTATGGTCCCGAGACCTTCTCTGGTTCAGTTCTGGAACAAGTTCGATTTGACCTGCGGGAACGTGATTGGAATGAGTACTCCATGATGGAGCTATCCTCAGAAAACTTTGGGCAGATCGATGGAGACCTCATTTTCTACACTATCCCAGGATCCCCTGAAGCAACCACTTATCCACAGATTTCCGAACTGTGGGTGGATTCACCGGCAGCTCAGCAAGGTAAAACTTACGAGTTTGAGGATGAAACCTGGATGGTCGGCATTGGTGTTCTAGGTGCCAATGAAATCTTGGACGATCTGGAAGAAACTCTGAGCTAGTTTCCTTTAGGCCAAGCAACCCCTTGCCGTTGTCCCTCCGCATATTAGGAGAGTCTCGATGACGAGGGGTTCTTCTTATTCGAAGAACTGTCTTCGAAGCACTATCTACTCAAACTCGAATTCGAGCTCAATCTTGGTGTCTTCGTATCGATCTGTATCGAGTTTCTCGGTGAATTCGTGGAGCAGGTCGTTGTAGAAATCAACCGCTTGATCTTCCAACATTTCTCGGTTAGTGGTTACTTGCTCGACGAAGTTCTCTTGGCTCATGATCTCAGAAACTACTTCTGCAGTATCGATATCGTCAGTGCTGAAACTGATCCAACCGTCATCTTCGGCTATGGTCTTAAACTTTAGATCGTCGTATCCGATGAAGATGAACTCAGGGATAGTGATGGAAAGCTTATTGTCACCTGCGGATTTGATTTCAACATCTGAGGCATCGATTCCGAGTTTTCCGGTGTAGCTGTATTGGACGTGCACGGTCTTTTGCGTGCCAGGAATACGTTTTCCACGAATTGTACGTTCAACGGTTTTCTCATGGATTCCAAGTGCTCCGGCGCTGAGAAGTACGATTTCTTCTTCGCGCTGGAGAGCTCTGATGGCCATGGAGTTATTGACAGTTGTGCGAGTTGAAGATGATGTCTGTTTACTGCTTTGCGAGTTAATTAGCAGCAAAATACCGCCAGTTATTACACCGATCAGTGCGATTAGCGCGAAGAGCCTAAGGAATAGCCTGTTTGGAAGCACGTGTTTTGCTTTCTATGAATGTGGTGGGCATTCAGTCTTCCGCGGTCTTTTTGCTATTAAACTGCAGGTGGTGTGTGGAAACTTAATGCGATATTGAGAGGATGTGTGGAATAGTAGCAACTTGTTTAACAAAGTAAAAACTGAACTACCACGTTTTTCATAGGGAATTTTGATCTTGTAAGCAATCGAAATCCCCCAATCAAACCAAACTATCCCGCAGTCAAAACCCGCTTCCGATCCCCACCAATAAACGCACCCATATGCACCAGCAAGCCACACAGTGGGCCAACTATAAGTGCAAGGCCAGCAGCGACGCCCAAATCAAATGGTCCCAGCAAGAATCCGACGGCAACAACAGTGGCAACAACCCATCCGGTGAGATAGATCCCGTGACGTTCAAAGGCGATCGCCGCGCAGCCGGACACCATCAATGAAGCGGTGGTGGTGGCGCCTAAGGTGAGCATCGCGAGTAGCCAGCCGGGGACTGCGAAGAGTTCCTTTTGGAGGACAACGTCCAGGATCCATGGGCCAACTAACCATGCAAGACCAGCTCCAACAAGTCCGACTGCCCACACAATTGCTAATGGACCCGCCAGGGTTTTCAATGGACCGGAGGTGCCTTTGACAAAACGAACGATGATCGCCGATTGGAATTGTTGCAGCGGAACCAGCAGGGGAGCGCGGGTCAGGATGACGGCGTAGGAAATGGCGGCCATCGAAACCCCTCCTGCAACGGCTGAAGGGTTCGTGAATTTCAGCAGGGTCGGGAAACCAGTAATGAGCACAGCCGTGGCACCGGATGCTGCCATCGCAAGCAGAGCCTGTCGGATGAAAACGCCACGGGGGACATCGGCGACTGAACCTAAAACGGAACGCACCGATCCAAAACACAGCACGATGACCAGCCACGATATTGATCCCACAACGGTGATGATCAAGAAAGCCAGCAATTGATAGCCCAGCAGCCAGGCCACGACAGCCAACACCATGCGGATACCGGTGTCCAAAGAAATCAGTGAGGCATACTCTTTCCACAGCTGGCATCCGGACAAAATTCCCGAGATCGTTGCTTGGATCGCATAGCTGGCAAGACCCACGGCGAGCAGTCCAACGCCCACACCTTGCAATTTGCTCAGCAGTTGGCCGATCCACAGCGGCGCCGACGCTCCAAGCACCACCAGGACAATTGCAGCGACCACGAAGCTAAACAAAAACGGCCGAAAACCAACAGAAGCCCCAGGAAGCCCAGAAACCCCAGCTGCCCCACTACGAGCCCGCCCGGCCGTCACCGCGCGGGTCGTCTCCTGCGTCAGGCCGGTCAGCACTCCGGTTCCTGCAAAGAACAGTCCCCAGTAGGCGGTGAATTCTTCGGAAAGTTGGCTGGAATCACCAAGGGCCCAGGCGGCGATGATGATGACGACGAACCCGGAGAGACCTGCGATGATTGTGGCCAGCGTCAGATAGCGCACTAGTCCAAACCACCAGAAGGAAACTCCGGCAACTCCAGATCGCGAAGCCAGGACTGCCACACTGCATCCAAAGCAGTGTGGTCTGTGGAGACTGCGTAGAGGTGTCGTTTCAGGTCGCGGGGTTCAACGAGTCCGTGTCGGCCTTCGGCAACGTAGGAGCGCACAGCTTTGAAGAATGCATCATCTCCCAACAGCTCACGCAGAGCATGAACTGTCAGTGCGCCACGTTTGTATACGCGGTCGTCGAACATATCCTTCGCGCCGGGGTTGGCCAGCAAGATATCCTTCGGCAGCGCCTCCAGGCCTCGATAGAATTCCAACGCACTTTCCGCGGCGGGCTTAACCCCAGCCGCCTCAAACCAGAGCCATTCGGCGTAACAGGCGAAACCTTCGTTGAGCCAGATGTCGTTCCATTGTGCGAGGCCGAGTGAGTTGCCGAACCATTGGTGGGAGAGTTCGTGGGCGATGAGTCGTTCCCAGGTTCCTTCGCCGGTGGCGTGGTTGGCTCCGAAGCTGGAGAGGCCTTGGGCTTCGAGTGGGATTTCGAGTTCGTCTTCGGTGATGACTACGCGGTAGCTGCGGAATGGGTAGGGTCCGAAGAGTTTTTCGTAGGCGTCGAGCATGTCGACTTGTTTGGCAAAGTCCTCCAAAATCCGCCCGCGAAGAGCAGCATCACCAACAGGCACATACGCCTCCACCACGACGCCCGATTCCGATACTCCCAAACTTACAGTGTCGTATTCTCCGACGTGGACGGTGGCGAGGTAGGTGGCCATGGGTTCGCGGGATTGGTAGTGCCAGGTGGTCATGCTGCCACTGACGTTTTTGGAGATGAAATCACCGGTGATAATGGCGGCGTATCCGTTGTCGGTGTGGAAGTGGACGTCGAAAAGCGCCTTCTCGTCGGGCGTGTCGTCGCAGGGGAACCAGCTTGGCGCGCCGCAGGGCTGGGCGGCGACGAGGGCGCCGTTGTCGAGCTCTTCCCAGCCGATCATGCCCCATTCGCTGCGCAGGGGGCGCGGGTTGCCGCGGTAGCGGATGGTGAGTGAAAATTCCTGGTCAACCGGGATTTGTTTGCGGAAGGTGATGCGCAGTTTGCGGCCGGCGTGGCGGAAGCGCGCGACTTGGATGTGGGTGCCGGCGGTGCCTTTGGCGGTGACTTTTTCCACGCGCAGGCTGCCGCCGAGGTCCAGGGTCAGCGCGTCGAGCGCACGGTAATTATCCATGTGCAGCGTCGCGGTACCCATGAGCAGGTTCGGTGCTACGCGGTAGGTAAGATCTAGCTCGTAGCGTCGGATGTGGAAGCCTAAGTTGAAATCAATTCCCGTGTAGGAATCGCGTGTACCAGGGACCGGGGTGGAGCGCAGCCTTCGCATAATCATAGATATTAAATGCTACCCTGCTGATCCAAAGTCTTCTCGATCCAGGTGTAGATCAGTGATTCCACAAACGCTGTCTGCTTATTATCGGCCGCGCCCGCGTGACCGCCCTCGGTGTTTTCGTAGTAGTCGACGGCCTGGCCCGCATCAAGCAAAGCTTGAGCAAAAAGGCGGGCGTGCGCGGGGTGGACGCGGTCGTCTCGGGTTGAGGTTGTCACCAATGCGGGTGGATAAATTCGCTTCTCGACGCCCACCACCGCCTGCACCGGCGAGTACTGCTCAATCACCGCCCGTTCCTCCGGATCGTCGGGGTTACCGTACTCCGCCATCCACGAAGCACCCGCTGACCAGGTGTGATAGCGCAACATATCAGCCAACGGCACCTGCACAACTGCCGCACCGAATGCTTCTGGGTACTGGGTTAACGCGCCACTTGTCAGCAAACCACCGTTGGATCCACCACGAATCGCAATCTGCTCCGGGGTTGCGTAGCCGCGCTCCACAAGGTCGGCGAGCACCGCGCGGTGATCCTCCCATACCTTCATGCGGTTCAGCTTGGTTGCCTGCGAATGCCATTCCGGACCGAATTCACCGCCACCACGCAGGTTGGCTTCTACAAAGTAGTAGCCCTTTTCCAACCAGGCGATGCCGCGGGTCGGGGAGTGGCTTGGGGTAAGGGAAACCTCGAAGCCGCCGTAGGCGTGGACCAACGTTTTCCGCTGGGCTGCCGAAGTCCCGGCAAAGTTACCCGTAATAAAGTACGGAATCTTCGTTCCATCCGCCGAGGTCGCCCAATGCTGACGAGTCTCCTGACCAGCATTTTCAAACTGCAACGGCGCCTTCTTCACAGCCTCAAGCGCACCAGGCAGCTCCGCACGCAGCAACGTTGGCGCCTCGGTGAAACTCGCTGCCTGCACCCAAATTTCATCGCCATCCAATGGGGAGGTAGCAACCACATGCGCGGTGACATGATCGGGAAGTTCCATGCGGGTTGGTTCCGCAACCGGATCAGACAGCGGCACGGAGACGATTTCTGTCGACACATTATTTAATAAGGTAAGCACCAAGAAATTCTTCGTGGTGGCAAGCCCCTGCAACGAGGTAGACGCAGAAGGCGTGAACACTTGATTGAAATCCCGCGCACCGTCCAAGAACGCATCCAACTCCAGGACACCCAAACCACCCGCCGGAATACCCGCATAATCAGTACGGGGATTTACAAACAGCCACTGATTCTTCACGATCACATCGCAGTCAGTCGGCACCTCCAAAAGCACCAAACCATCGGCAGTCTCCAGGTACGTTTCCGAGTTGTAAAAATCCAAGGAACGTGAGGCAAAAATCCGCTCAAACCCAGGGGTGGAATCCCGCCACGCATGAGTCGCAACATCCTCACGCGCACCCTCAAAAAACACTGATGCCTGCTCAATCGGGGTGCCACGCTTCCACGTCACAGCGCGCGCCGGGTAGCCAGAATCCGTCAACGAGCCCTCACCCGTATCCGTTCCGACTAGCAAGGTGTCCGCATCAATCCACGTGACGCTGGACTTGGCCTCAGGTAACTCAAAAGCCCCAGCCCCCACGAATTCACGAGTGGCCAGGTCAAACTCCCTAATAACCGTGGCATCCGCACCACCCCGCGACAGCTTAACTAGCGCTAAATCCCGCTCCGGAGAACGCACAACTGCGCCCTTCCACACCCAGTTTTCGCCCTCGGCCTCCGCCAACGCATCCACATCAATTAACACGTCCCACTTAGGCTGCGCACTGTAATAGGACTCCAAGGTGGTCGTGCGCCACACTCCACGCGGATGCTGTGCATCCCGCCAAAAGTTATACAGCTTCTCACCGCGTCGGCTCACATACGCAATGCGATCATCGGTGTCCAACGCAGCCAGCAGCCTGGCTTCCAGGGCGTCCTTGGCTGGGCTTTTTAGCTTTTCGACGCTTTCCCCCGACCACTTCTTCGCCCACGCGAGCGCTTCCGGGGTGTCAATGTCTTCGAGGAACGTGTAATCAGTCATGAAGTTCAGGTTAGTGATCTTTTGACCGGCAGGTTTTTTAAGGCGTCTTCTGTGGACGCCTTCAAATGGATCAGCCGACGTAAACTTGAACCGAGTGGTAGCGGCCGTTTTCAAAATCTACGCGCACACCGATTGCCCCGGTGTCTTTTTCACCATCAGGATTCAGGAACGATGTGTTTTGTTTGATGATGGCGATTTCGTCTTCAATCCTCTCTGGAGGAATTGAATTAGCCACAACATAGAGCCGTTCTGATTCGATGTAATCGGTAAAGAACATGTCCTCAAAGAAAACCAGCTCGCCATTGACAGCGCGCTGGTAGTAATCATTTGCAATGGCTTCAGCGTTGTCGGTTTTGGTGCGGCCAGTGGCGATGAAAAATTCTTCCAACGCGTTTTTAAATTCAACAGCCTTTTTATCTCTAGTTTCAGAGAGGCCGCTGCTTCCAAAAGAGCTAGAGCCAAAGCTTAACTCCGCATGAGCCATACCAGCACTCATTGGAGAAATAAGAACGCCGGAAATGAGCACTGCCAGGGCTTTAGTTAAGGAGCTTCGCATTGTTAGAGCATACCTACCACCATGTTGGAGGCGCTAGGCAACAAGAGAGTTTTATGTTTATCGACGCCTCCCTCCACCCACCCTTCTGCCCACGCAGGTGCTACCGTGAGGCTGAAGTGGAAAATCTACTAGGAGGGTATTGTGTGACCGTCCCTGAAAAACTCCCCGAACAGCTTTCTGAACAGGTTTCTGATCAGCCACAACAGCGAAACTATGTAGTCATCGCAGCCTTGACTCTAGCTGTAGTTGGCTTTGTCCTTGCCTGCACCCCGTCGGCTGTATTGGTAGGCCTAATAGCACTAGTGATCGCTTTCTTTATAGCCATTATTTCGCTCTGCATTCCGGGCTGGCCGAAACGCCAAGGAGTGTATGCGTTGGTGCTGTCTGTTGTGGGATTCGCGGTGGGAGTTGTCAAAATCATGGTGATTTTGGAAGACATGATGAGCTGATAAGCCCATCCTTTTGTGTTCCTGATCCAAGGGCACTCAAAAGGATCCACCAGTTTTAGAAAGTAAAAATCCAGTAAATGGAGTTCATTTACTGGATCTACTTATTTGAATCAGGCATCAAACAGAGGATGAAACGCTGGTTTAAAAGTCAGCCTAAACGCCAACCTAGACGCCGATTTAGACGTAGGTTTCAACACCGGCAATGTAGAAGTAATTGCCAAGCTTTCCTACTTCCAAACCAAATTCCTTGTCGGAGTCTTCTGGGTTTTCTTCTGCCCACTTGATGTCTGCTTCGATGTTGTCCAGGATTTCTTCCGCCTGCTCCTCGGTCAGCAGATCGATCCAGTACTCGGTGAGCTTCTCTTCGTCGTAGACATAGAATTTGCCATCCACGAATTCGAATTCACCAGCAAATGCGCGGTTGAGGAGGCCGGTTGCTTCCAACTCCTGATCGGCGTGAAGGACGTGGCCGTTTGCGGCGATGAGTCGTTCGTATGCGACCTCAAGGCGAACTTCTAAAGGCTCAACTTGTGGCTCTTCAGGGCCGGAAGATCCAAAATCGAAGGAGCTGGAGCCGGCGCTGAAGTTAGATTGTGCATGGGCAACGCCAGTTGTTGCGGGGAGGATGAGGGTTCCTGCGATGGCGATGGCTGCGATTTTACGGGTGATGTTTTGCATGCCTGAATATTAAGCATGTATTAATGTTCGATGCGTAAATACTGAAATATACTTAATTGCCTACCCCGTTTCGGAGGTATTTTTCACTGTATTTTCTCAGAAAAGCCACAATCGATCGCGTGAAACTTTACTTCCAGGCACCCACGAAAGAACCCCAAAGAACCACCACAGAACCCTCAAAGAACCACCAAACATCCACAAGAACCAAAAAGTCTAATTAGTGAATTTGGTTGTAACTAGGTAGTAAGTCCCGTTCTTAACTCCAACAGCCACTCCGAACCTGAAGGGAGCCCCGGAAAAATAGGAGGTAGCTAGTCGCTCGCCGCCGTTGATTCCTTCAAAAAAATCTTGAATTTCTTTTGGAGTAACAGTACTAACCGAGGAAAGTGTGTTGCTGGCAGGGTCAAGTTGTAGGTAACGACCATTGCGTGTAATTGTGTGACCTTTGATGACGGAACGCAGTAGAAGTTCCGCGCGCATCTCAGCATTGAGGTCTAGTGAGTGGCCTCTGCTTAGCCCGTAGTCCTCAAAGGCTTTCTCAAGTTGAACGGCTACTGGGTCGGAGTCGTGGGACATGCCCAAGTCGAAGGTGCCGGAGCTGAGGCTGGATTGTGCACTTGCGGTTAAGGCAGTGGCTGGCAGTAGGAGGGAGCTTGCGATAATGGTGGCAGCAACTGTGCGAACAATGTTTTTCATGCTTAGAGCATAAATTAGTTCAGCATTATTGGCAGGGGGACCGCAAAAGCGTCAAAAGATTTTTGCTTTTCGACGCCACCCTCCGGTACAACCGCCCCCGTTAAAACTTAGCCACCAATGATTGGGCCAGTTCCGCCGCTGGTTTCTTTCTGAACAATCGCCACGTAGTAAAGATCGCCTTCTTGGGCAAAGTCGGCCACATTGTTTTCAGGGGCTTCCTGAGCATCGCGTACTGCTGTGGAAAGCTATGACAGAAAGTCGTCTGCTTGTTCCTCGGTGAATACTTTGACCAGGTAACGGGAGCTGTCGATGAAATTGAATTCTTCGTACTGGCCTTCAATGATTGGAAGTTCATTGTTGAGCGCCTGCTGGAGCAGTTCGGTGGCCTTGTCTTCTTCGGTCTGGTTTAGCTTTTGGCCGTATGCTTCGCCCAGGCGCTCGAAGCCTTTCTCCAGTCGAGTGGTGGTGGGAAGATCGGCGGTGGATGATCCCGTGTCGAAGGAGCTGGAGCTGGAGCCGAAGCCGAAGCTGGATTGTGCGTTCGCGACAGCCGCAGTTGGTGGAGCAGCGCGCCGGCAACGGCGAAGGTTACAAATTTACGGGTTAGGTTCTGCATTCCTAAATAATAACTATGTGCATTTTGATTTGCTGTCCTAGGTCATACCTGCCCAGCAAATCTCGTGGAAGGCCTAAAAAGGATTGCTTTTCGACGTCCCCCTCCACAACCCTCCACCCACGGAAATTCAGACCCAAACCGATCTGCTTGCGAGCTAAAGCGCTACGTGCACAATGTAGTAGTACTGGCGATCTTTGCCGGAGGCTACACCAATCTGAATCAGGTCCTCATTGGGGTAAATTTCCAGATCTGCGTAAACGATCTCAAGAAGCGACAGCTCAAAATCAAGGTCATCACTGCTGATTTGATCAACGGAGGCGTAGTGGATTCCCGGAGAATTTTGTTCCACGTAGGAGCCATTCTCGAACACTAATTCGCCGCGTAAAGCGCGTTGTAAAAGATCGTCAGCTTTAGCCTGTGCCAGTGGATTTAGCTCGTGCCCTAGGGCTAAAAAGACCTTCTTGTAAAGCTCTGTGTATCTAAGTGATTTTGCATCTTGATTGATGTTGGTTTCTACCGAGCTGGAGCCTGAAACGAAGCTTGATTGGGCGTGTGCGATGCCCTGGGTGCCCGCAAAGATTATCGATAGGGATAAAGCGGTGGAAACGAGTGGCTTGATGAGGGCTTTCATAATTGGAGAGTAATCGAAATATGGATCCAAATATGGCTCGCTTACGTATGAAATACTCTGATAATCCGTGAAATTCTTACTTTGGTGTATGTATTTTTGAAACTCAAATGAATCTTATCTTGGCCTGTGAACGTTAGAAGAGGATTGGGCTAGCGGTAGGTGTTGATTATTGATGTAGAGTTCCCATTCCCACTAGGGATGAAGTTTCTTTCATTTTAAAGCCTCTGTCTTGACTCAGAAGCTTCTTCGACCTTGTGGGATGAGAAGGATGATGTTCCAGCCTCGGGCAGTAGTGCGTTAACGCGTCATGTGCATAAAATTAAGAATTGTTTAATTTTGCAAAGCTGGGCACCTTGAGACTTTAGTCCTCTCGGTCTATGACTCTTCAACTTGTCTTTTCTACTAGAGTTACCGGAAAGATAAGGCTGTTTTGGAATGAGTTTTTCCATAGTTTTAAGAATCATCAAGCGTACTTTACATTGATTAATGTAGGGTCGCTGGCAAATTACTTGCAGCTTACTTTGCCGTACTGATGGAAATTTATATTGAGGAGACATTTTTATGACAGTGTTTATTGGGCATACGAGATTTAGTGTGCTTGATCCTTCGTCACCTAATTGGCAAATAACCCAATCTGGCCGTTTTAAGGATATAGACGAATACCGTGAGTATTTGTTCTCACCTGAGAGACTTGAGCTGAGAACTGATATTTTCTTGAACTATAGCCTCCCGGAATTGTCTAAAGCAGCGGAAAAGCACAGGATAGTTCATATAATTTCTTACTCTGACTTACTTCCGGACCCTTGGAAATCCAAGTTGGAGAAAGCAATTGAGAATTATGACTTTTTAATTGGTGACCTTAGGCGTAGCGGGGGAGCAATCCTGGATCCCCATATGGTTGCAGAAGAGGCGCTTGGCGGGAATGGCATATATGGGTTATATCGATTAGATGATGACGATATTTTGTCCTCAACTTTTTTCTCTAATTCCGCCAAGTATCTGAAAGAAGAGTTTGCGGGAATGCAAGTTTCATTTTCAGATGGGTATACAGGCTTTTGGCAAAATAACTTTATTCGCAACGTCAGGAAAGTTCATTGGCCAATGTTGGCAATTGGCTTTATGAACATTTGCTCAATTAAGGAAGGGAAAATAGTTTCGCAGCCACGTCCTGCGCCACACCATATCGCTGATCGAACTAATGCCGTAATCATCGATCCTCGACACCCTAGCTATCTTTGGTTGCGTCATGAAGACCAGGACACTGCGAATAAGTTCTCTTCGTCTCAGATACGACAAGAAATTTTTCGAGATATGGAGAAGTATAAGCCTGTAGCGGTCGACTTTAGTTTTGATCCGGTCTTTCCTGCAATCGCAAAGTCTATTAGCATGCACCGACAATATTCTTTGATGTCAGAAGAATTGGTTCTTGTCAGCCCCTCTGAGTTCTTACTTCCAAAAGAAATGAACTGGTTTGAGCTGATAGTAGAGCTGGATTGTGGAAAAGGTATAAAACAACACAATGCACTGATTAGTTTCACGATCAGAGATTCTGATGGTGATCTAGTAACCGAACCAATTGAGGGGGTACCTTTTTCTAATGATCCCAAAATTAAGCACTACCGCTATCTTAAAACTGAGCTAGGGGAGTCGATTTCCAATGTTGAAATCCAATTGCCTGAAGGCTTGACTTGCAATGAGCTTCGAGTGCAACGGTTCCTTAACGTGGAATCAGAAATCAGGGTGAAGAACGCCAAGGTAAGGGAATTAACCTAGGCCCTGAGCGCAATTTGATGAGACTTGACTGTGTGTAGATGTTATCCGGCTCATCAAATGATCTGCAAGGAAGTAAAACGCGCTCTCAATCAGGAAAACTTGACGTTTGGATTGAGGATGCGGATCTGGTAGTTAAATGCGATTAGGCCACCAAATTGAATTGATTTTCGACGTTCCCCTTAACCAAAACGAACGGACCCCTTCTCTTTCAAAGAGAAGGGGTCCGAATCTAAAACTAGCTACAAGTTAGATGCCAAACGCGCGAGCGAAGGTATCCCATGAGCCGCGGAGGTCATCCTGCCACCAGCCCCATGAGTGGGTGCCGGTTGGGCGGAGGTTCCAGTCGGCTGCGATGCCTGCGGAATCAAGCTTTGCCTTGAGATCGTGGGTGCACTTGTTGGTTGCAGCCTCGATGATTCCACCGGTGAGGACGGTTTCAGCCATTGCGACGGACTGTACCTGCTGGTTGAGTCCTTCGAAGCGTGGGCTGTCTACGGACTCCCACTTGCCGGCGAGGCCGGATGCGTTGGAGACATACAGTTCAGTTCCGCGCAGCTTATCCGAGTTGATCAGTGCGTCGTTGTAGATGTTGTATTCGCCACCACGTGGTCCCCACATCTGTTCTGGGGTTGCGTTACCGCGGTCAAGGGTGAGCTTGAGGTATTCCCATGGAAGCAGGCTAGAGGTCGCTGCGCATCCGGAGAATGATGCTGCTGCGTCGTAGAAGCCTGGGTAGTGCTGAGGGAAGATTAGGGAAGTGGTTGCAGACATGGACATGCCAGCGATTGCGCGATGTCCGTCAGCGTTGAGCTTTTCTTCCAATGGTCCTGGGAGTTCCTTCACGAGGAAGGTTTCCCACATCTGCTTGCCACCGAGGCTTTCGTTCTCTTCTTCCCAGTCGGTGTAGTAGGAGAACTTGCCCTCCATTGGGATGACAACGTTGACGTTCTTGTCCAGGTAGTAGTCAAGAGCGTCGGTCTGCATGACCCAGTTAGCTGCGCCTTCGCCGCCGTCGCCACCGTTGAGCAGGTAGATAACTGGACGAGGTCCTGCGGACTCATCTGCAGTGATAACTACCAGAGGAATATCGCGATCCATGGAAGGGGAGTAAGCCCACATTTCCTTCACGCGCTCGTCTGCTTCGTTGACGTATGTACGCCAGCGAGGTGCAGAGGCTTCATCTGCAGGAGCACTATCGGAGATGGTGGATAGTGCAGTATCGCCAGCAACGTCTGCTGGGGTTACTTCGGCAGCGCCTGCGGTTGATGGCATGATAATGGTGGACATCGCAATTCCCAGCGCGATGGCTGGTGCAGCGATGCGGCGAAGAAGCTTCATACGTCTTTCCCTCGTGAACTTGTGGTTGGTAGCCCTGGCTTTACCTTTAAGGGGCAAATACGGGACTGCAGGGCGTAAACCCACTAATCGACAATATAAACCAAAGTTGGGCTATCAGCCCGACACGCTACAACTTAAAAAAATCATGTGGCGCACCTTTCATTTACATCGAGAACTCAAGCAACAACGTTAACAGGCGAATCCGGATTTCGGAATCGATAACTCTAAAAAATGCGTTCACACTAATGCCAGGTTGTAAAACGAGTTATTGAAAGTGAGAGGTTTTGCTCCGGTGCAGGGTTTATGGCAAAAGGGTTGGAGTTGACTGAAGGGGGTTAGCGTTTCCGCTGCATAAGAGGTGAATCTGAAAATTTCATGATTGGACAGTGAATTTAATCCGTTATTTTCTTGACAGGAGATATGTTGCTAACGTGGCTTTAATTGAATGGTTAAAGGCCTGCTGGTTGCGTGTGATGAGCTTCCGGGTCGTTTTATTTTGCTCTAAAAACTCTTGAAAGAAGATACAGCTTCTTTGTGGGGTAAATCTGGATTGGATAATTAATGCGCAAGCCAAAAATTATGACGGTGTATGGCACTCGGCCTGAAGCAATCAAAGTTGCACCCGTGATTAAAGCTCTTGAACAAGACGAACGCTTTGAATCAGTTGCGGTTTCCACTGGACAGCATAAAGAAATGCTGGATCAGGTAAATGAGATGTTTAGTATCAAACCTGCATACGATTTAGGATTGATGAACAAAGTCTCCACTTTGAGCGGAGTTGTATCAAAAGCGCTCGAAGGTCTTGACGAGATCATTGAAGCAGAAAATCCTGACGTAATTATCTCTCAAGGAGATACCTCCACCGCAATGTCAGCTGCGCTGGCAGGCTTCCATCGTGAGGTCAAGATTGTTCACCTTGAAGCGGGGCTGCGTACAGGTAATATTCATTCGCCTTTCCCAGAGGAAGCTAATCGTCGAATTATCGGGCAAGTCTCTGAGTTGCATTTAGCTCCAACTGAAATATCAAGAGAAAACTTGCGACGAGAAAATTTCCGCAGCGCAGATACTGTCGTTGTGGGAAACACTGTCATCGATGCACTGCTTGAAGCCGCCACATGGGAAACCACATTCGAGGATCAGCGACTTAATGACTTAGTGGAGTCAGATCAACGAATTGTGCTTGTGACCACCCACCGTCGTGAGAATTTGACTGCAATGTCGGAAATTGGTGGAGCTGTCCAGCAACTGGCTGAAGCATATCCTGATGTGATTTTTGCCCTCCCACTTCACCTAAATCCCAAGGTTCGAGATATTGTTTTGCCAAAGGTAGATACTTTGCCAAATGTGATCATCACTGATCCGCTCCCATATGATCAGTTCACCAAATTGATGGCGTCATCCACCTTGGTCTTAACAGACTCCGGTGGAGTCCAGGAGGAAGCACCGGCGTTTGGAAAGCCTGTTCTGTGTATGCGCGAAAATACAGAGCGGCCGGAAGCAGTTTTGGCTGGAACGGTTAAGCTTGTGGGTACTAATCAAGCGCGGATCATCACTGAAACCAGGCTGTTGCTAGATGACCCAACCGCATTTAGTGCTATGGCTCAAGCTATCAATCCCTATGGTGACGGTAAAGCTGCAGAACGTTCAGTTGCCGCGATTGCAGCATTACTTGGTGTTGGAGAGCGTCTCCCTGATTTTCAGCCAGAAAAACCTATCGAACCCGGTTTGGATGAGCCACGTTTAAGTGATCAGTTGTGAAATGAACTCGTCTTTTGTGAAACTCATTCGGGAAAGTTGATCAAGCCGAAATTCCAAATTGAAGAAGCATTATGAGTACAATTGCGCAGTAAGATTGTCTGATACTTGGTTGATCTCGTTGTGGGCATTGGCAAGGCAAATTTGAGTTTGTGATTTTAGATGGGCTTGTAACGGTTAATGAGAATCCTCGTGTTATCGCAGTATTGGTACCCGGAAAATGGTGTGCCACAGCGGCGATGGTCCTGGCTATCCAAACTTTTAATTCGTGAAGGGCACGAAGTTGTCGTGATCTGCCCTCCTCCCCATTACGAGCGGGAAGTTAGTGTGGGATCTTGGCTTCGTTCTGTTATTAAGCGTAAACCGAGCTCTATTGAAACAGGGCCGTCTGGAGAGAAAATAGTCCGTTCTGGCTATTTTCCAACCGGGCAATCAATCACAATGAAGGCATTTAACCAGGGCGCCGTTGCTTTGGCAATGCTTTGGCGTGGGTCGTTCCACGGTCGCACTTTACGGGACTTCAAACCTGATTTAGTAATTGGAACTGTTCCTGCAATACCGACTTCGCTAATTACTCCGCTAATTGCTAAGAGGTTTGGTAGTCCCTATGTTATTGACTTGCGTGATACTTGGCCTGAGCTTCTCAATGAGGGGCGAAAGTGGAATTCTGCAGTTGGTGCGCAGTCAATCCGGCAAAAGATTCTAAGTAATGGTCCCTTGCAGGTAATGGGTGTGATTGTTAGAAGGTTGATGTATCGATCTTTTAAGGCTTCAGCAGGACTCATTTTTACCTCGAATAGTCATGCAGCTTGGTTGTCTAAAACCATGCAGATGAAAGGTAAGACACTAGTTACCGCAACGATTAGAAACGTCTTTCCACCTAAATCTGACGCAGTTCGTGCATCTCAAGGTATCGAAAATGAGGCCACATTACATGTACTTTACGCAGGTACTTTAGGTAGAGCTCAAAATCTAAATAACGTACTTGAAGCTGCGAAAATTTCTCGTGATAAAGGTATTCCTGTTGAATTGCGTTTTGTTGGAGCAGGTGCAACCAGCAACGAACTTAGAAGGAAAATTGCAAAAGAAAACCTTCATGCGGAAGTAGTGGGGCGCGTTCAAGCGAGCGAATTAGCGAATCACTATACCTGGGCGGATACTGCGTTAGTACATTTAACTGATTGGTCAGCATTGGACCATGCGGTTCCGAGCAAAACCTATGAATTAATGGCCAATGGAATCCACATCACTGGCGTTGTTAAAGGCGAAACGGCATCACTAATTAAGGAACTGAACTGTGGTGTAGTGGTCGATCCAGAAGACCCAGAAGCTTTAGCTTCCTCATGGGGGAAGTTGTTAAACGACCGTTCTCAACTTCAGGTTTCAGACACTGCTCGTGAGTGGGTTATTACGCAGCGTGATGAAATCGTCCCACAAGAACTTTATGCTTTTTTAAGCGAGCTTGGAATACAATGAAAAGAGTTTTCTCCCTAGCGACGATTGTAGCTAGTTATTTGTGGCTTGATTCTCGAAGCTTTATGCAGAAATTGGGGGAAAGGGCACGCTTAAGCAATCTGAAAATTCCCAAGTTCCTATTTCTGGCTGAACTAACAGGGACTTCCCCTGCGTATAAATTTGTCGAGCTTGGTGAATTATCGAAGGCACAAGAGCTGTTAGTAGAAAAAGGGAAGCTCTCGATTTCTGAACGTAGACTTAATAATCGAGTGACTCAAACACTCAGTGAATTAAGGCTAGGCCCTGTTAAAAATACTGTAAGAGTCGCCAGGTATGGCGAAAAAGTAAAAGTACTGTATTTCCTGACTAATTCGCTACCGTATACCACGTCTGGCTATACAAAGCGCTCCCATTCGATTCTAGAAGCAGTAATAGATAATGATGTTGAGATTCAGGCAGTCACACGGATGGGGTATCCATTAACCATTGGAAAATGGCCCAACGGAAACGCACAATTTGTAGATGGAGTTAAATACCATCGAGTTTTTCCATGGATATTTTCAAGAAGAACTGAAAAATTCTACGAAAAATCTGTTGAACTACTTTCGGATTTGGCCAAGGATCTCGGGGTAACCGTAATTCACACCACGACCAATTTTCCTAATGCTATTGTGGCAAATCGTGTTGCTTCAAAATTAGGACTTCCTTGGATTTATGAGGTTCGTGGAGAACTTGAGAGTACTTGGCTCTCTAAGTTGCCAAAAGATAAGCAAAACAAGGCAGAGGAATCTGAATACTATCGATTAGCTAGACAACAAGAGACAAGCTATGCAAAAGCTGCCGATGCTGTTGTTGTTTTGAGTGATATTTCAAGAAAACAATTAGTTGAACGTGGGGTTGACCCAGAAAAGATTTTCGTAATTCCAAATTCTGTAGAACAGAGTCTGTTTGAAAAAGAGTATGACAAATCTGAACTTCGGAGAAAACATGGGATTTCTGAGGGGTCCATAGTCGTGGGAACTGTTTCCTCTGTCGTCCAGTACGAAGGGCTAGATACCTTGCTTAAAGCTTTGATGAAGCTGCCTCAACAGTATCGTGGCCTAATTGTTGGCGATGGTGTAGATAAGCCAAGGCTAGAGAGCTTAGCGGAGTCTTTGGGAGTACTTTCACGCGTCGATTTTGTTGGAAATCAAAATCCACAGACGATTGATGAATGGTATAAGTTGCTAGATATATTTGTGATGCCAAGAAAAGATACTCCTGTTTGTAGGACTGTGACGCCTATTAAAGCACTCACCGCACAAGCTCTAGGTATTCCTGTAATCGCCAGTGATCTGCCGGCATTGAGGGAAGTAACCGGAGGAATTGAATCGTATGTGATTCCTGAAGATGCTCGAGATTTAGCGGACAAAATTTTAGCGGCTCGGCCTCATACACAAGGGGTAGAGTGGGCGGCTTCTAGAACTTGGAATGTAGCGGCAAAAAACCTGAATAGTATCTATCAGCGTGTTTTTTCTTCATCTCAGGCGACGTAGGACTTTGCGTGGTCGATTGTATCTCTTGCACATTAAAATATTAGGACCTGCAGCTTCTTCATAAATGATCCTGAAATGACGGCTGAGGAAGGTATACATTCCTCGATAACTCACCATTGAGAATTTGATGTGAATTTGTTCTAAACGGGGCGGATAACCTACTTATGCAAAGAAATCTGTGTGTGATCAACTGTTTGTAGGCCAGTTAAGCAGAAGAACCCGGCCAAATCAACGGCTGGCTTCCTGCCAAAAAAGCACGAAAAACCGGCCACCTCCCCACACCCACCAGGTGGCCGGTCTTCACCGCATGCTCAAGCATCTATGTAAAGCCTGACGGTCATGTGCACCGCCACCGTTAGATAAGTTCCTCCTCGACGCTTCCCAACCCTTTTCACAAGTGGAGCGTCTTAACAGGAAGGAACACGAAAGAAGATGACGGTACACAGTGAGCCGTTGTAGAAGATATCAGGAGACTGGACTCTCAGGGAGTTTCCAACCGTGAAATCGCCCGCAGGCTTAGTATCAGCCGCGACACGGTAGCGAAATACACCAACATCGAAGACTTCTCCTCAACACCACCCACATCCACTAAACGCCCAGGTATTAAAGCACTCGACGGACTCGACGTCATCATCAATGGCTGGCTCGAAGACGATAAGAAACGCCCCCGAAAACAACGCCACACCGGCCGACGTGTCTTTGACTGCCTCGTTACCGAATATGACTACACCAGCTCCTATTCCACAGTTCAGCGCTATATCAAACTCTGGTGCCAAGACCACCGTCATCTAAGGGACCTGACCCCCATTTGGTAGACACCTAACATCCCAACAATCTGGGACTGAAAGGTAATCTCCACACCATGCCACGCAAGACCTATACAGAGGAGTTCAAGCGCGACGCCGTCGCCTTGTATGAGAACTCCCCGGGCACCTCGATCCAGACCATCGCCACTGATCTTGGGGTCAACCGGGCCACGTTGGCGAACTGGGTGAAAAAATACGGCACCGCGGCTCCCACTGAAAAACCCTCGCCAGCCTCGGTGAACGAAGCCGAGCGGATCCGAAAGCTGGAACGCGAAGTCCGCAAGCTCCGGGAGGAACGCGATATTCTGCGAAAGGCGGCCAAGTATTTCGCGGAAGAGACGAACTGGTGATCCGCTTCCGGTTCGTTGATGACGCCCAGAAGAACCACTCGGTCAAGCGGTTATGTGAAGTGCTGAAACTCAACAGATCCTCCTATTACAAATGGAAAAGTACCTGCTCAGCCCGCAGCAAACGCCTCATGTCCGACGCGATCCTCGGGGCCCGAGTCAAGACGGTCTTCACTGCTGAACATGGTTGCTATGGTGCCAAGCGGATTACCGCTGAACTCAAAGACCAGGCCGATCAGGCCCCCGTGAATCACAAGCGAGTTGCGCGGGTCATGCGTGAACTCAAATTGTTTGGTTACACCAAGAAACGCAAGGTCACCACCACCGTGTCCGATCAGAAGAAACCAGTGTTTCCTGATCTGGTGGGCCGTAAATTCACTGCTGAGAAGCCAAACCAGCTCTACGTTGGGGATATTACGTACCTGCCGATTGCGGATGGGTCGAATATGTACCTGGCGACGGTCATTGATTGCTATTCCCGCCGGTTGATCGGCTTTTCCATCGCGGATCACATGCGCACCAGCCTGGTCCAAGACGCACTGCTCATGGCCAAAGGCCAGCGTGGAAGCCTGACTGGGGCGATTTTTCACTCGGATCACGGCAGCGTTTACACCGCGCACGCATTCCAGAACACCTGTAAGGAATTAGGGATGAGGCAGTCGATGGGATCAATCGGTACCAGTGCGGATAACGCCTTGGCTGAGTCTTTCAATGCCGCGATGAAGCGGGAGGTCCTTCAGGATTCCAAGACATTCATGAACCAGTTGATCTGCCGCCGAGATGTTTTCCGCTGGTGTACCCGTTACAACACGGTGCGCCGGCATTCCTGGTGTAAATATCTCGCCCCTGCGGTGTTTGAGAAGCGCGGTTCTGTTATCCTGAAATCTGCTTCCTGATTAAATCCTCCGTGTCTACTATCCGGGGGTCGGGCCCAAGTGATGGTTATATCGAACTGGCCTGGGCACCCGGTGTTGCTCAGGTTGATTTCGGTCAGGGGAGAAGCAATCATCGCAGGCCAGCGTTTGACGCTGCACATGTTGGTCGTAACGTTCCCGTTTTCGAATGCGCGCTTTGTCCAGGCCTATTGTTAGGAACGGCTATTTTGAAGCACCGTGGTGACAATCGTGAAGCAGTATGGTGAGCTTCGTGAAGCGGTAACCGGAGTCAGACCCCACACTTCTAGTATCACCCGACAACTCGGTCAGGTGAACACTAGAAAGGACCTGGACCGTGACCAACTACCAGTTGATCATGACTCTGCTTCTTCGAGGCAATTCATACAGGACAATCCAAGCCCACTGCGGTGCCGCACACGCCACGATCGCTAAAGCGCGTAAAGCACTCGACCAACACAATCTCACCACCGAAGCCCAAATCATGGGCCACAGCAATGAAGACCTGGCATTGATGATCGGCGATGGCCGGGCCACCACCGCAGGTGAATTCGTCACCATCGACATCGACACCATCATAAAAGCCAGAACCGGCAGGAAGAAAACCCCACTCAACGTCCTGTGGGCCAACTACCTGAACATCCCCGCACCTGAAGGGCTTCGGCACTACAGCTATGAACGTTTCCGGCAGCTCGTCAACCGTCACATCGCCGCGCAAGGCCTGACCACCCGGGTCCACCACATCCCAGGACACACTTGCCAGGTCGATTGGGCTGGAACGACAATGCAGTTGATCGACCCGATCAGCAGGAAAACCACCAAGGTCAGCATCTTCGTCGCCACCTTGCCTTACTCCGGGTTGGTCTTCGCCCACGGTTTCCTCGACCAACGCCAACCCAGCTGGCTGGCCGCGCACCGCCTGGCCTTCGACTACTTCGGGGGAGTACCTGAAGTCATCGTCCCGGATAATGCCTCCACCGCATCCAATGTCATTACCACCGGGGATAGGGCACGCAGGGTCAACACTAGTTATGAGGAGTTTTTGACCCACTACAACACTGCAGCATTGCCGGCACGCCCCCTGCGGCCCAAGGATAAAGGCAATGTGGAATCCGGGGTCAAAGTCATCACCAACTGGGCAATCCTGAAACTAGCGGGCAGGGACTTCACCAATCTAGACGACCTCAACGGTGCTCTTCGGGGAGCAGTTGATGAGATCAATGACCGTACTCCCTTTCGTGACCAGCCATTATCCAGACGCCAGATCTTCATCGATGCTGAACAGGACCTCTTGGCTGAACTACCTCACCAGCCGTTTGTATCCACAGTGTGGAAGAAAGCGAAGGTCGCTCCGAACTGGCACATCACGGTATCCACGGTGCATTACTCCATCCCGTATACCTATGTCGGTGACACTGTCGATGTCCGTATCCGCGGGGAGCAACTCGATGTCTTTGCTGGTGGCATCACTATTGCCACTCACCAGGTCACCACCCAACGAGGTGCCTATGTCTCCGATATTGCCCATTGCCCACCGGGAATGGAAGATCCCACCCAACTGTGGTCAGCGGCTTATTTCCTCAATCAGGCGGCCAGGGTCGGGCCGTTCACCAGGAAGGTCATTGACGCACTGTTGGCGGCGAAGCCGATTGTGGCTCAGGGGTATCTTCCTGCCCGCAATATTCTGGGGATGGGTAAAGGTGAGAATAAAATAATCCTCGAAGAGGCATGCCGCCGACTTGTCGGGGAGGGTGATCAACCCCGGGCCGTGTCCTACACGGCGGTGAAGAACATGATGGCTGCGGTGCGTAGCGATCTGGCAGCTCGCCCCACGACCACTACTGAGGTGCCACCGCGCCCGAGTGGTCAAGATCAGAGGTCACAGCATCATCGCAGGCGGGGTGGTTTGTTGGGCGGGGCCGACCAGTTCAGCTTGGATTCCTTGATGGGTAAGAAGGAGGATCAGCCGTGAGCGATTCTTCTATTCACCTTGATGACACCTGGCTGGAAACATTCACCAGGCTACGGATGACCGCATTTGGCCAGACAGTCATCGATATCGCCAACGACGCCGCTTATGACGAGTGGACCTTTTCCCAAAAGATTGCCTTTGCCCTGGATAAAGAGGTTGCGGCCCGATCGGAACGCCGCTTTGCAAAACTACTCAAAGCATCCCAGTCGCCAAACCCTGATGCTTGTGTAGAAGAACTCGACTACCGACCTGATCGCAACCTCACACGTCGAGTTAACGACACGGTTAGCTCACTGTCAATGGGTAGCCAAGGCCACCAACGTCATTGTCCTAGGCAAATCATCGGTGGGGAAAACCTATCTGGCCTTGGCGTTGTTGAATGCTGCCTGTCGGCGGGATTACACCGCCCGGTTCTTCCGGACTGATGATCTGGCAGCGCGGCTGGCGGTGATGGATTACCACGATCCCAAGCGGGTTCAGTTCATTAATCAGATCACCACGACGGATCTGCTGGTTCTGGATGATTTTCTCACGACCCCGATCAGCGCGGATACGGCTAATGTGTTGTTCAATATTTTGGCCGCCCGCGAGGAGCGCGGATCGACGATGGTGACGTCCCAGTTCAATCCGGAAGAGTGGTACACCTCGATGGCGGACAAGGTGGTCGCGGAGTCATTGCTGAATCGGCTTGTTGGTGGCGCTGAGATCATCAACCTGGATGGTCCGAACATGAGGTTGAAACCGACGATGAGTTAACAGGCGGTTAGGCGTCCTGGTGCTGGGGTGGGTGCTGCTTCACGATGCTCACTCCAGTGCTTCACGTTTGTCACCACGGTGCTTCAAAATACCCGTTCGGAACACCTATCGCGGGGAAACCGCGGAATGCGTTTGTCACGGACTGCGCACCATCTTCGAACACATCGGTGGCGTACCCCGCCAATTGATCTTCGATAACGCCACCGGCGTCGGGCGACGTACCGGCACCACGATTATTGAGTCGAAGCTGTTTTCCGCATTCAAGCTGCATTACCGAACGTCAGCACGTTATTGCAATCCTTATTTGCGGTAATGAGAAAGGAAACGTAGAAAACGCAGTCGGCTTCCTACGCCGCAACCTCATGGTCCCAGAACCTGTTGCCACGACCTTAACTGGGCTTAACACCACGTTGTTCACCCAGTGCCAGGATTTAGGGCTACAGCCACACTGGCGTAAACAACAACCCATCATTGAGCTGTTTTCTGAAGATGTCGCAGCCTGCCTGGCTTTTCCTGGAGTTGGGTTTGATCCGGTGCGCTATGAATCCCGTAAAGCTGATAAAACCGGCACGATCACCGTTGAGGATAATTTGGGCCCGACCCCTGGAAAGTAGACACAGGGGATTTAATCAGGAAGCAGATTTCAGTATAGCTAAATTTCTGCTCTCAAACACCGTTGGTGCGAGATAACCACACCAAGAATGCCTGCGATTTGTGTTGTACCAGGTCAAACCACCGAAATGCCTCCCGGCGGCACACCAACTGATTAGCAAACGTCTTGGAATCCTGCAGCACTTCCCGTTTGAGCGCGGCATTAAACGACTCCGCTAGTGAATTATCAGCACTGGTGCCAACAGCACCCATCGACTGACGCACACCCAACTTTTTACAAGTGTCCTGAAACGCCTGCGAGGTGTACACGCTACCGTGATCCGAATGAAAAACAGGACCCATCAGGCTGCCTCGTTGGCCTTTAGCCATCAGCAACGCATCCTGAACCAATGACGTACGCATATGATCTTCCAATCGCACAACCCACCAACCGTGCTAAGAGTAGCAATCAATCACCGTCGCCAAATACATATTCGACCCATCAGCAATCGGCAGATAAGTAATATCCCCGACGTAGACTTCATTGGCCGCCAAAGCGTTGAAATGACGCTTCACCAAGTCCGGAAACACCGGCTTCATTGCTGCTGGGATGGTGGTGATGACCTTGCGTTTCTTCGTGAAACCAAAAAGCTTCAGCGAAGACATCACTCGAGCGACTCGTTTGTGGTTAAACGGAGTTGTTGTACTCGGCCCGTCATTAAGCTCGGCAGTGATACGTTTTGCACCGTAGCAGCCGCGTTCTTTCGTGAAGATGGACTTGATTTTCGCTCCCAGGACTGCGTCGCTGATCAAGCGGTTGTTCCTGGTCGGGGAAGTCTTTTTCCATTTGTCATACGAGGAGCGGTTGATTTTCAACACCTCATATAACCGCTTAACTTCAGTAGGTTTTTCGCACGTCGTCAACAAACCGGAAGCGGTTCATAAGTCTTGTCTCTTGCCGGGAAAATATTTAGCAGCTTTGCGCAGGATGTCGCGTTCTTGCGCGTTGTAGTGCGTTTTCCTTCTTTAGCTGTCGGATTTGTTTAGCTTCAGATACCGCCACAGATGGGGTTGTCCCTTGGGCGTTGTGGTTGGATCCGTATTTGATGATCCAGTTTTTCAGGGTCACTCGGTTGATGCCGAGATCGTTGGCGATCTGTTGGATTAAGGCCCCATCTTCAGTTCTCGTACAAGGCGACTTCCGTCGCGTTTGCGATCCTCGGAGTAGGTCTTGGTTGGCATGATCGGTAGGTTACCTTTCTGTCCCAGAATGTTGGGATGTTAGGTGTCTACCAAACAGGGGTCAGGTCCTTTCCACCTCGCTGGCCCCTCTTTCCATGGTCGACTGCTTACCGTAGCGATTCGTCATGATGTCATCGAGATTTTAGATGAAACCTCACGCCCCATCGTCACATTCCCCAGATCCTATGATCACCAAGATACGACCGTATTCACGCCATTATCACTGCTTCCAGCGTTGATTACTAAACCAGGAGCCTGGGACAACTCACCTGTCCGCACCTTATTGCCCGCCACTGTTTGTAGTGTACTGGATAAAGCTCATGCCGCCGACCGGTCCCGGTTGCTCGCTGGAATCAACCGGGCTAGCACCGCTACATCTTTTCCCAACATTATTGCTGCCTGGGAGCAGCTCATCGAAGTCGGCCAAAATATTGCCGGACCAGGCCTAGGCATGCTTGCCAGGCGTATTGCTCGAGGCAGCGACCTGGACGTACCTGAGGTAGATCTATCAGTCTATGACCTGCTACCAACCAACCGACACACCCACCACACCGATCAGAACGCGCCGGTTATGGCATGACCGAAACAATCACCGCAGCCGATATCATCAAGATCGGCAAATCCACCTCACTAACATCGACGGTGCTGGCGCAGTGGGCAGAAAAAGGCACTCCGAAACAACTCGAATACCTCCACGGACTCCTGCTTGCTTCAACAGCAATCCCGTCATAATGCACGGGCTGCCAGGTTGCTTCGGGCAGCGAAACTTCCGATGAACAAATCCCTTGACGGCTATGACTGGACGAGTATCAGCTTTCCCGACAGTTACGGACGTGAAGATATCCGGTCCCTGGATTTTCTAGACTCCGGCGGTGATCTGGTCTTGTATGGCGATGTTGGTATTGGGAAAACTCATCTGGCGTGTGCTCTTGTTGCCCATGCGTGTCAGCAGGGTATCCCTGCCAGATTTTTTACTACCGCCTCACTGGTAGCACATCTACGTCGAGCGAAAGACGCTGACCGGCTTGATAAAGAATTAATCAGTCTGGGAAAGAACCGTCTGCTGGTCATTGATGAATTCGGCTATCGACCCATTGATACCGAAGGTGCACGGCTGTTGTTCCAGGTGATCGCTGATGCGTATGAAAGGCGCAGCTTGATCTTGACCACCAACTTGGCTTTTTCCAAATGGGGTGCGGAGTTTGGTGATGATCACATGGCGGCTGCTGTGATTGACCGGATTGTCCATCACGGGAGGTTGCTGCACTTTAGTGGAGAATCCTACCGCGTCAAGCATGCCTTGATGAGCTAAGTCCTTTTACTTAATCCATGATGATTGGAGACTTTTTCTCATGACCATATCTATTCCTACAACTGCCAAAGATCAGTTATGTTTTCCCAGTGATGAGCAGGTGTTGCTCACGGAAGCGATGGATCTGTTGACTTGTATCGAATCAAGTTTGCGGGTTGCTGATGTTGATACCCAGATGGCGGTTGCACGGCTTGCAGAGCTTTATTTAGGTGCTGATGATGGTGATCATTTCCAGACAGTTTTGGCCAAGATTACCCAGTTAAGAGACCGGATTTATATCCAGGTTGATCAAGCTGATTAAGGGTAGTTAACCCGCCGTGCTCTTTTGGCGGGTATTACTGCTGAAGTGGTAGGTTTTTCCGTGCTCTTTTGGCCAATAAAAAGTTGACAAAACACAGAAATCACCAAGGTAGATACTAAGGGGCAATAGGACAACGAGTAGATGCCGACTATAATGCTATTCCGATCATCCCAAGGATGATAAAAATGATGGAGATTGGAAGCAGTCGGCCAAGCAATTGAGGCTTTTGATACCAGCGGATCCACCACACTCCGGGGATGAAAAGGCCAATACCTAATGTAGTTAGTCCCAAACCGAATAGCACGTCTGTAGCCAGGTTGAATACCCCCATTATCATTAGGCATGTACCGAGTGCGAGGATTAGAACCATGCCTGTGGTGGGCCAGGTATCGCGATGTCTCTTCAGCGTCAATGGTCTCATTGTCAGTCTTCGTTCACTTCGCTAGAAAGCAATAGTTTTGGTGGGAGGTAATAAGACTTCATCTGGTCAATGATTTTGTCTGCCTCCTTAGTTTTTTGGGAGGCCTTCCTTTCTCCCCATACATCGTAGGGCTGAGCGATTGATTCAAGATCGCCATCGCCGATGATTTCTCCTTGGTGCATCCAGATAGCGTGGTTACAGTTCTCACGAATGACTCCTCCGCCGTGCGCAACTAAGAAAACCGTACCGGAACGTCCAAGAAGTTCGCCCATTCGATCCTTGGCTTTTTTGGCGAAGGTGGCATCTCCAGTAGAAAGTGCTTCGTCGATTAGTAGGATGTCGGGCTTAATTGAAGTGGAAATAGCGAATCTAAGTCGCGCACCCATGCCTGATGAATAGGTATTCATCGGGCGATTGATCGCGTCTCCTAATTCAGCGAAGTCGATAATTTCTCCATAGAGTTCATCGGCTTGCTCAGGTGACATGCCCATTGCTAGACAACCAAGCCTGACATTAGCCGCACCAGTAAGGTTTGGTTGCAATGCTGCAGATACGCCTAGTAGTGAAGGCTGAGACGAGACCATGATTTCACCAGAAGAAGTAGCATCGCCTCCAGAAATCATGCGAAGCAAGGTAGATTTACCAGAACCGTTGTGTCCGAGAATACCAATAGCTTGTCCTGCATAGGATACTAAGGACACATCGGAGACGGCTCGTACCTCAGTTCCACGTCGACCATGGCTGCGATAAGTTTTGCTGACGTTTCTGACAAAAACAGTAGGACTTGAATAGTCAATGGTGGACTCAACGGACATTGACGTACCTTTCCTCTGCTTGCCAAAAATAAATCAGTCCGATTGCGACCAACCCAAATGACCAAGCACATAGTATTAGCCAGGTGTCGTAGGGCGGGATTGTTTGATACAACACAACGCTCCGAACTGCCTGAATGAATCGGTAGGCAGGGTTAAGGATCATAATTTCTTGAATAGTTGGATTTGTAGCAAATCGTTCGATAGAGAAAAATACTCCAGAAACATAGAACCATGCTCGACCAGCAACTGGTATTAGGGACTTCAAATCTGGAAAAAACGCAGTTAATCTCGCGACAATGAGCGCCAACCCTAGTCCAAAAATATGGATAAGGACGTATATAGGTAGGACTAGCAACATTTCCCAGCCTGGAGGGGTGCCCCATTGAAAAGCCAATGCAGCTATCAATGCCACAAGGGCAGGAAGCGAATTATTTAGGAACTGACGGGCGATGCGAGCTATGGGGATGGAAGCTCGAGGAAATGAAAATGCGGCAATCATGGAGCGTGATTCTTTGATCATGCCAGATCCTGTGGTTAACCCGCCCTGGATGAAACCAAAGAAAATCACTCCAATGATGAGGAAACCAATGAAGTTCTCGACTCCCCTGGAGGTTTTTAATAATAGGCCAAACAGTAGACCATACATAGCTACATCGAGAAGAGGAGAGAGGACGAGCCATAAACGTCCGAGCAGCATATCTCGCGGCGATTCGAATGATCTCCCTCGTGCGTCTGCGAAGATAAAATGACGTCTATTCCAAATCTGCGCGAGGTAGATGTTGAATTTGGGACGAGAATGCAATGGATGCAGATTGCTGGAATCCACGATAATTGCTGATTTATCACCTAAGAACTGATCGGCTGTGGTCTTTTGAGGTTTTTGAAACATGAAAAACCTTTCCTTGAAAAACCTGCAAAAGAGCAGAGGATTTAGCTATCCATTTTGGTCTGAGAACTGTTAACCATAATAGAACTGCAACGACAACCTGATTTACAAACGTGTCATATGATAGCAGAATGCCCCTTTGGAATAATTTTGCTAGAACTTTGCGTAAACTTCGAGATTTAAGTCTAATGAACGAAGCGCAACATGTATTTCACGAGTTCAAAGGTTTTTTGAGTAGAAATGCGCGGGAATTAAGAACTGGGGTATGGCATTACCGAAATGGTGGAATTCAACAGCTAAAATTATGGCGTTGGAATCAAGCTGCTCAACAGCCCACCGCTTCACGCAAAGCAAAGCTCACTGAGGGCGGACTTCGCCGAGATTTCCCGGGCCTGCGTGATGCTTGGTCGAAAAAGTCTGGGCAAGATAAAGAGTGGGCAGCTGCAAGTGAAACCTACAATTACCGTAACGTTTTTGCTCAGGGCTGGATCCTGGCAACTAGAGTCAAGGATCTAAATTTACCGCCTTCTTGGGTTGAAATTAGTTTTGGAGAGAAATATTTTACTTGTGATCCTGCACTGAAAGTTGTCGACAAGGGAAAAAGTGATCAGCTAAATCAACTGTTGGTTCTTGGACAGGCCACAGATTCTGAAAAAAAGTTACGGTCTAGCCAGGAAGTAGCTCAGGAACTTTATTCAATACTTGAAAATAAGCGACAGCCGTGGATTGAGTTTGATGAGGCAGTAACTTGGCTGGGTGGTCGCTTTGTAGTGATAGCCAGACACGGTGCGGAAACTCGAGTACACGTAGATGCTATGGCTAGTCGCTCATGCTACTGGGGCACAAGTGATACGGAGGAAGTGGTGCTGGCCTCTCATAGTGCGCTCGTTGCTGAATCAGTGGGTGATTTTTCTAGTACGCGTGCAAGATGGGTGCTCAATCACCCTGAGTATCATAATCCGGCTGGAGTATATCTGCCTGGGACCATTACGCCATTTGATCGAGCTCAATTGGTTTTTGCTAATTGTTATCTAAGCATTAACGATAACGCTGTGCAGCATAATCGATTTTTTCCCCCTAGTGAAAACAACCCTGTGTCAGTGCTTTCTGTGGAGGCCGCAACTGAAGCCTATCTTGCTGAGGTGCGGTTTCAAATGGACGTAATCTTGAGTTGGGAGCCTAGATCTGTATTTGCTCTGACCTCAGGATCTGATTCTCGTGCAATTCTTAATGCCTCTCTAGATCTGCTTCAAAAAGCAAAATCTACTGCGATGACATACCATTTTTTTGAAAAGGATGCAGACCATACTAGAAAAGATCTACTTGGAGCGAACCGTTTAGCTGAAAGATCTGGACTAAAACATCGAATCCTGAACCTTAAACCTTGGGATCCTGCAGCCCGATTTGCAAAATTATATACTAAGACGTTTCCTGTTTGGGCAAGATTTGGGGCATTGGCACGAGCCTGCTACGAGGGATTGAGCGCAAAAGAGACTCTTATTATCGGTGTAGGTGGCGAAATCGGAACTGCCTTTTACTTGGAGCGAAATAGTGCAACAGTAACTCCAGAGGTGTTGGCTGCAAAATTTACTCAAGACAGTTTTCAACATGACCCTAAGCTAATTGCAGAATTTGAAAACTATATGGCTTACTCGCAGCTTGATTCGGAGCATACAGGGAGCCTCGATTTATATGATCTTTTCTATTGGGAACACAGGATGAGCAGCTGGGCGGCCTATTGGTATTCAGAACTAGATTTTGGACCAACCGTGGCGCTACCTTTAAACTCGCGTCGGGTATTCTGCGCGATGCTAGGCGTGCCTTTAGAAGATCGAGTGAGGAAGTCCGTCTATGGAACCTTGGACTCTTGGGCAAATACAATAGCCGAGAATCTTAGCTCAGGAGGAGACAACTAGAAATGAATATAAAAAAGTCAGTGAAAGCAGCACGCACGGGATTCTGGCATTTGAGGCAGGGAGGCCTTCCACAATTATGGAAGTGGGCAGTCCCTCGCCTAGTTGCAAAGGGAATGATGGCTCCGAGCTTGGGTCCCTGGGATGTTAAGAGCGTGCAGGACTATGTTCCGCTTGAGTTAACTAAGTCCTATGGACATCTTAAAGTTGCAGCGATACTTGATGATTTTTCTCTCGCTGCGTGGGGCGGGGAGTTTGATCTGTTGCAGGTTAGGCCATCCACTTGGCAGGAACAGTTAGAGGAGCAAAATATTGATTTGCTACTTGTTGAATCGGCTTGGAACGGTAATCACGGTGCCTGGCAATATAAGCTGACAGGTCCGAATGCACCCGGCCCAGAGCTGGTCGATTTAGTTAAGTATTGCCGAAAAAACAGCATCCCTACTGTGTTTTGGAACAAGGAGGATCCTCCGCACTTTGAGGATTTTCTCACTACAGCTAAGCTCTTCGACGCTGTTTTTACTTCCGACTCCAACCGGATTGCTGCGTACGAGGAAGAACTTGGACACGATCGAATTCAATCTATGGCTTTTGCAGCCGCACCAGCAATTCATAATCCAGTCCGGGGAAGTTGGCTCCATCAGGAGGGCGATGTCGCCTTCGCTGGAATGTACTTTGCACATAAGTTCACTGAGCGGCGTCAGCAAATGGAATTACTTTTGGATGCTGCCGTGCAGGTTGGACCACGCATGGCGCACGGGTTGACTATCTTTTCCCGATTTCAAGGGCACGACGAACGCTACCAATTTCCAGCGCTATTTGACCGTTTCGTCGTCGGTTCGTTGCCTTATCAAAAGATGCTCACGGCTTACCGTGGTTTCAAGGTATTTCTCAATGTGAACTCCGTCGTGGAAAGTCCTAGTATGTGCGCTCGTCGCATTTTTGAGATCACAGCTAGTGGTACACCCGTAATAACAACGCCGAGTAAAGCAATCAGTAACTTTTTCCCTCCTGAAGAAGTGACGGTGGTAGAAACTCACGAACAGGCACAATTGGCTATGCGGGCATTGGTTAACTCTCCGCAGCTACGAGACCGTATGGTTCACAAAGCACAGCGTCGAATTTGGCGGGAGCATACCTACTCCCATCGAGCTTCCCAAGTTTTAGAAGCCGCGGGTATCGATCATGAAAAATCTTCCTTGCCAACTGTTTCTGTCATGGTGTCAACCAACCGGCCACACCAGATTGAACATGTACTCACCCAGGTTGCACACCAGCAGCAAGTAGAGATGGAGTTGCTACTGCTTTGTCATGGCTTCGAACCTAAACATGACATGATCAGCCGTCGCTGTGTTGAGTTAGGCATTCAAAATTATAAAATTCTAGAGGGGCCAGCCTCCTGGAGCCTGGGAGCTTGTTTGAACAAAATTGTTGAGGAATCCAGTGGGCAGGTGTTGGCAAAGTTTGACGACGATGATTTTTATGGCCCTAATTATTTGTTAGATCAGCTCAATGCTTTGAATTACTCAGGTGCAGGGCTAGTAGGGAAAGAGTGTAGTTATCTTTACGACGCTGAGACAGATGTGATAATTAGGCGCCGTCCGGAGCGTGAACATATATTCACCAGATTTGTAGCTGGACCCACTCTTGTTGGCTTCGCTGAGGTATTTCGCGCCCATCCATTTGCAGACAGGAGTACTGGAGAAGACACAGAGTTCCTTCGGGACTTGGTGGAGGGCGACGTAAAGATTTACGCTGCAGACCGCTTCAATTTCTTACAGATGAGAAATAAAACCGGACACACATGGAGTGTGTCCGGGGCAGAATTATTGGCAAATGGCGTAGTAGAGGTAATCGGTCTACATATCGACCAAGTGATTTGTTAAAGACTAGAGACCTGTGAATCGGAGTCTGAATGAGCAGGTAGGCAGAATTCCCAAAAGGCATTATATAGCAACTGAATATTTAAAGCTCTAAGTATGTACCTTGAGCTGTGTAGTAATGACTCTCGAGTTCCACAGGCGATTTGTAAAGTAAGAAGGACTTTCAGATAAAGTTTGATTCTAAAAGCCCGCAACAACAGAGAAGAAATTACTCTGGTAATCGATTGTGTAGCTTTCCGAGGTACAATTGGCAATAGTATTCACATCAATAGGGAAGCGGATCGGATCAGTGATTCCGCTGATTGATCCGCATTCAGCTAAATGATGCTTCGCGTCAAAATGTGGATATGTCTAGCTACGAATCAGTAGCTAATTCATCCGGGCCCGACCCCCGGATAGTACACACCGAGGATTTAATCAGGAAGTAGATTTCAGGAGAACAGAACCGCGCTCCTCAAACACCACAGGAGCCAGATATTTACACCAGGAATGCCGGCGCACCGTGTTGTAGCGGGTGCACCAGCGGAAAACATTCCGGCGACAGAGCAACTGGTTCGCAAACGTCTTGGAATCCTGAAGAACTTCCCGCTTCATCGCCGCATTGAATGACTGAAGCAAGCGCGTTATCCGCACTGGTACCAATTGATCCCATTGATTGCTGGATCCCTAATTCTGTGCAAGTGTTCTGGAACGCGTTCGAGGTATAAACACTTCCGTGATCTTCAGTGAAAAATCGCACCCGCAAGGCTCCCTCGCTGGCGCTTCGCCATTTTCAGCGCGTCCTGTACCAGGGAGGTACGCATGTGATCTGCGATAGCAAAGCCGATCAACCGGGAGTGTCCCTATGTTTTTGTCAAGAGGTGGGCCCTGTACTCAAGAAGCAGCTTCGGGGGTAGCTGTTGTTCTTGATGTTGGGCGGGGGTGATTGGCTGGTCGACCGGGACGTTGTTGACCAGTTGATCGTGCTGACGGTCGCTTACGTAGCAGCTCTGGCCGGAACCTCCCGGAAGAATTCAGCTCGGGTCAACATCGCGTAGATAACATTGCACCTGCGTCTGGCCAGACACATGATCGCAGCGTTATGGCGCTTGCCCTCAGCCCGTTTTCGTTCATAGTAGGTCTTCGACGGCTCGTGGAACCGGATGGATGCGAATGCAGAATAGAACAACGCATTCTTGAGTCTTTTGTTACCTGATCTGGCAGGGAATTCACCACGGATGGATGTGCCGGATCGTCGTGTTACCGGGGCGATCCCGGCGTACGCAGCCAGGTGGCCGGCGGACCGGAAATCAGAACAGTCGCCGACGGCCAGGAGGATATTGGCCGCGGTCTTGATGCCGACTCCCGGCATGGACATCAAGACGTGGTGAAGAGGGAATTCTTCGAGTAACTCCTCGACTTGTTCCGCGATGGTCTTGCGTTGTTCCAGCAGGGCTTTGATGTTGGTGGCTAGTTGCGGGATGACGATTTCTGCAGCTGCAGTGCCAGGCACGGTCACGGTTTGGGCTTTCAGTCCTTCGAAGATTGCATCCACCAGTTTGGTGGGGTCCTTCTTCGCCCGATTGGTCATCCAGCCCAAGACTCGGTGATAACCAGCCTTTTTCATCTTCGTCGGTCCTCCGTAGTGGATCAACATCTCCAGCACCAGGGGCCTGGTGATGATGTCACCGACGAGGGCTCGTTCGAAGCTGGGGTGGATCTGAGTCAGCACGCTGCGCAGTCGGTTGATGGTTCGGGTGGCGTCTTTGGCGATGTCGTCATCAAAGCCTGCCAGCATCTTCAACGCTGACAGGACCTCGTTCTCCCGGTCTACGGCCCGTAGGGTGTGTGGCATCGTCCGTGCGGTATCAGCGATGATGAAGGCGTCCTGCCGGTCGGTTTTAGATCTGCCAGGATACAAGTCTGCGGCTTTGCGCATGGCCAGACCGGGGAGGTAACCAACCAGGCAACCGGCATCCCTGGCCACTGCAATGGGGAGTGCTCCGATGGTGTTGGGCTGGTCAACGACCATCAAGACCGTACCGTGATCCTGGAGGTCGGTAAAGACCTTCCGCAGCTGGTCCTCGTCTTGGGGTAGGGGTTTGTCGTAGATGATTTCGCCTGAATTGAGCATGGCGCAGGCGTAGTGGGCGGTTTTACCGACGTCGAGTCCCATGGTGACGTCGACGGTGCCGGTGGTCATGGCTGGCCTCCTTGTGGTGTCGTGGCAACAGTGACAGGTACAGCGTTGTCGCTGGTGTCGTGACATCCGGTGCTGGCACCCACGTTACGAAGAGACCTGGTCAGGCAGACCGGCCGTGTCCCTATTAGCAGTCAACGGTTGTCCTGGAGTCCCGGCGGCAATACCCCCCCGGATTATGTGAACTACAGGGCGATTAAGCCATACCGGGCCCAGCGACTATCCCCATTATGGGGACACCATCAAAGTAACGGGGAATAGCAATCAATGACTGTGGCCAGGTACATATTCGACCCATCCGCAATCGGCAGATAGGTAATGTCCCCGACATAGATCTGATTCGGCTTGTCAGCGGTGAACTTCCGGCCCACCAGGTCAGGGAACACCGGCTTCTTTTGATCCGACGCGGTGGTGATGACCTTGCGTTTCTTGGTGTATCCAAACAGTTTGAGCTCACGCATGACCCGCGCAACTCGCTTGTGGTTCACTGGTTCATGACCTGTCTGGTCTTTGAGTTCGGCGGTGATTCGTTTGGCCCCATAACAACCCTTTTCGGCGGTGAAAACCGCCTTGACCCGGGCACCGAGGAGAGCGTCGGATATGAGTTGTTTTCTACGGACTGAGCTGCTGTTTTTCCATTTGTAATACGAGGACCTGTTGAGTTATAGGACCTCGCATAACCGCTTAACCGAGTGGTTCTTCTGGGCGTCATCAACGAACCTTCAAGCGGGTCACCAATTCGTCTCTTGCCGGGAGAATATTTAGCGGCCTTGCGTAGGATGTCACGCTCTTCCCGCAGTTTGCGTACTTCGCGTTCCAACTTTCGAATCTGCTCGGCCTCATTCACCGAGGTTGATGAGGATTTCTCCGCCATGAGACTGTTGGTGCGGGCTCCGGTTCCGTATTTCTTCACCCAGTTGGCTAACGTGGCCCGGTTGATCCCGAGGTCAGTGGCGATGGTCTGGATTGAAGCCCCCCCGGGGAGTTCTCGTACAGCGTGACGGCGTCGCGCTTGAACTCCTGGGTGTAGGTCTTGCTTGGCATGGTGTGGAGATTACCTTTTAGTCCCAGAATGTTGGGATGTTAGGTGTCTACCAAACGGGGGTCAGGTCCTCCTGGGGTTGCCCGCAAATCGTGGACACGTAGTTAAGCTACTTTGTGGTTAAGCAGCGACTTTCTTTCTATCATCTTGCTCAGCGATCCGGGCCTCGAAATCGACAGGGCTGATCATCCCGATAGCTGAGTGCCGGCGGCGCCGGTTGTAGACAATCTCAATCCAGCGAGCCGCAGCCTTTCGGGCTTCATCTCGGGTTGGCCATTTCTTCCGGTCATAAAACTCGGTCTTTCGCGTCGACCAAAATGATTCTGACATCGCGTTATCAAAGCACACACCAGTCCGACCGACTGATTGAGCAATCCCTAATTCTTGGCAGACCTGCCACAACTGTTCGCTCGTAAACTGAGTGCCGCGATCCGCATGGAAAACCAGCCCCTCAGGTACATCACCGCGCAGGGTATGTGCCATGCGCAATGCACGTTCAACCAAGTGAGAATCTTGTACGCTGTCCATGGCCCAGCCTAAGACACGACGCGAGTGCCCATCGCGGATGACACACAGGTATAGCCAGCCTTCCCCGGTGCGTAGATAGGTAATATCCGACATCCACACTCGGTTGAGCTGACCTTGGTCAAACAATCGTTTCACCAGGTCTGGAAGCGTGGACTTCCGCTTGGATTGGATCGTAGTTACCGGAACAAAAGCCCTGGGTGAGACACCTTCAATGCCCATCAGTCGCATGCGTTTCGCCACGGTTTTACGATTAACTATGATGCCTTCGTCAACGAGTTCTGCGGTAATACGCGGGGCACCGTAGACTTCGCCAGAATCCTCCCAGATGTCATGAATACGCTTATCCAATTGGTCGAGAAATTCCTGACGGGTATCTTCACCGCGAAGTCTGGTGGCTTGAGCTTTAGCCCATTTGTAGTAGCCAGAACGAGAAACCTGCAATAGTCTGCTCATTCTTTTTATGCTGTAGTTTGCCTTCTCCAGCTGTATTAGCTCAAATTTTTCCGATCGCGTTGCTTCACAGCGAAGAAGGCGGTGGCTTTTGACAAGAACTCATTATCCATCTTGACCTCGGCCAATTCACGGCGCAGACGAGCGTTTTCTGCACGAATATGGACCTGACCCCCATTTGGTAGACACCTAACATCCCAACAATCTGGGACTGAAAGGTAATCTCCACACCATGCCACGCAAGACCTATACAGAGGAGTTCAAGCGCGACGCCGTCGCCTTGTATGAGAACTCCCCGGGCACCTCGATCCAGACCATCGCCACTGATCTTGGGGTCAACCGGGCCACGTTGGCGAACTGGGTGAAAAAATACGGCACCGCGGCTCCCACTGAAAAACCCTCGCCAGCCTCGGTGAACGAAGCCGAGCGGATCCGAAAGCTGGAACGCGAAGTCCGCAAGCTCCGGGAGGAACGCGATATTCTGCGAAAGGCGGCCAAGTATTTCGCGGAAGAGACGAACTGGTGATCCGCTTCCGGTTCGTTGATGACGCCCAGAAGAACCACTCGGTCAAGCGGTTATGTGAAGTGCTGAAACTCAACAGATCCTCCTATTACAAATGGAAAAGTACCTGCTCAGCCCGCAGCAAACGCCTCATGTCCGACGCGATCCTCGGGGCCCGAGTCAAGACGGTCTTCACTGCTGAACATGGTTGCTATGGTGCCAAGCGGATTACCGCTGAACTCAAAGACCAGGCCGATCAGGCCCCCGTGAATCACAAGCGAGTTGCGCGGGTCATGCGTGAACTCAAATTGTTTGGTTACACCAAGAAACGCAAGGTCACCACCACCGTGTCCGATCAGAAGAAACCAGTGTTTCCTGATCTGGTGGGCCGTAAATTCACTGCTGAGAAGCCAAACCAGCTCTACGTTGGGGATATTACGTACCTGCCGATTGCGGATGGGTCGAATATGTACCTGGCGACGGTCATTGATTGCTATTCCCGCCGGTTGATCGGCTTTTCCATCGCGGATCACATGCGCACCAGCCTGGTCCAAGACGCACTGCTCATGGCCAAAGGCCAGCGTGGAAGCCTGACTGGGGCGATTTTTCACTCGGATCACGGCAGCGTTTACACCGCGCACGCATTCCAGAACACCTGTAAGGAATTAGGGATGAGGCAGTCGATGGGATCAATCGGTACCAGTGCGGATAACGCCTTGGCTGAGTCTTTCAATGCCGCGATGAAGCGGGAGGTCCTTCAGGATTCCAAGACATTCATGAACCAGTTGATCTGCCGCCGAGATGTTTTCCGCTGGTGTACCCGTTACAACACGGTGCGCCGGCATTCCTGGTGTAAATATCTCGCCCCTGCGGTGTTTGAGAAGCGCGGTTCTGTTATCCTGAAATCTGCTTCCTGATTAAATCCTCCGTGTCTACTATCCGGGGGTCGGGCCCTATCCGCATCACTGCGGCCATCATCCGAGCCTTGGCGTTCACGTTCGAGCTTGACCCACTTGCCTAAAATCCCTTCGGCTACACCGATTTCCTTGGCCACATGCGCAATCGGTCGCCCCGACTCGATGACAAGCCTGGCAGCCTCCTGCCGGTACTCTGGGGTGTACTTCTTCCTTGACGAGCTCACAATGAACATCCTCTCCTACGGACACAAGATCCGTACAAATTGGGTGTCCACTACTCGAGGGTAACCGCAGAGCATTCTTAGCGTTTTAGAAAGAGTTGGGGAGTTCTTTCTCGTGAGTTTCAGATTTTTTCAACCCATTCGCCGTCTGCCCTATTTAGAGCGGACGGCGCTTTGTTCGTTGAGTGGGTTCTTTGTTAGGAAATTTTCGCCACGAGATTTTTTGAGAACTCATTAGAGACGATTCGCGGCGCACGTTCTAATTCTAGACTTAGTAAGTCTGCGTCCAAATTGGGGGCAGTGAAACGGGATAAAGCATTTGAGATAGCGTAGGCCAGATCATCTGCATCATTAAAGGTTTCAAAAAGCGATGGAGGAACACCTTCGACGAGTGCTGGTTCATTAACAGTGATGATGGGATTGCCAAAAGTTAGGTGTAGTAGAGCTGCACCTGAATTTAAGGTACGTCCATATGGGATGATTCCGGCGTCCGCAGACTTTACAAAAAGTTGAACCTGTTCAAAAGGAACTTTTTGTGGGTGGATAGTTACAGATGGTTCCAAGGTTGCCCAGTTAATGAAATCGTTTGCCTCTATTGAGCCATCAGCATCTCCTGCAACAAGGAGGCGTAGAGGAACATCTGAGCTTGCTGCAATTTCCCTCCATTGCTCCATCAACATTTTTAAACCTTTATACGGTTTGATAGCACCGAAAAGAGAGATTACGAACTCTTCCGGCCGAATTCCTAAAGATTTTCGACACTCAGCTTTGGGAAGAAAATCTGGATATACATTCCGATATGTAGGATGTGGAGCGTAGATTGTCTTCTCTTGGGGGATAGACGCAAATTCGCGCATCGATGAAATTGCCGCTCGGCTCATTGAGTGGACTACATCGCAATGGTTAATGATGGTTTGCTGTAGCTCGATCTCAGCGTCAATGAACTTTGCATCGTGGCTTAATTTGTTATGCAAGGTGAAAGCAAACTTAATGCCTTGATTCTTTAATCGATCAAGTTCAGTACGAGTTTCCTTAACGCGTCTTTTAGCTTCTTCGGCGTCAAGTGCTGTGGCCAGGATGGAATTAATCCAATGAAAATGAATTACAACCTCATCGGCAAGATTCTTCAGCTTATCAACCTTGCTAAAAGTATTGAATGGAATCAGTTCAGTGGGCGCGATTCCATAGCTATTGCAAGAACTATAGAGTAATGCTTGATAGGGATTCATTCTGGCAACTGGAGTATAGGCAAGAAGGATTTTCTTCTCACCCTGTGCGTAGGGCAAGCTATGTATTGCTTCTGTTAATGGAGGGCTCGCTTGTGGAGTCCATCCAATGAGATTACTTTTCATTCTTGAGTTCCTTCACCGTTTCGTAGGTTTGGCGATAAATTTCACTGTTTCCTGACCATTGGCGTTCAGTTGAAACCCATTTTCGTGCATTTTCAGATAGCGATTTGCGAAGCTTTGGATGCTTAATTAGGTAATCTAACTTAGTAGCTAAATCCAATGGGTTGCTTTCTTTGAAAGTCAAACCGCGTTGTGGTGGGTCTACGATCTCGATGAGCGCTGGAAGATCTGAGGTAATAACAGGAATTCCAGCAGCCATGGCTTCAAAAGGCTTCAGTGGGGTAACCAATCGCGCAGCTCGCTCATCGCGTCTTGGCACGACGAAAATGTCAATGAGTCTGTAGTAATCAGCGATATCATCATGAGGTACAGAGCCTGTGGTGATTACGTAATCGCCGATACCTAGATTTTCTGCTACTTCACGAATTTTTGATAGTCGAGGCCCACCTCCAACGAGCAGACAGGTGACATTCAAGCCTTTCTTCCTTAGTATTGCAGTTGCCTCAACAAGCGTTTCCTGAGATTCCCGAGAATGGTCGAGATTGGATACATAACCTACAATGAACTCTTTTGTTAATCCGAGGTTTTTTTCAAGGTTTTCGTTTTTTGGCGCAGGAATGAATTTTTGTGCGTGGACCCCGTTGGGAACTACTAAAATCTTCTCCGGATTAATTCCCCATGTTTGAATCTCTTCGCGCATCGTTTCAGATATTGTTAGAACAAAATCTGCTCGTATTGCGCAAGCCCGCTCAGCTGAAAGTCGCTTCTGGTAAGTTTCACTTTCAGACTCTCTTTCAATTTCTGCAGTCCATGTGCCTTCGAAAAAGGAACGAATTTCATATACAACTGGAATTCCAGTGGCTTTCCCGATAGCTAGGCCAGCCTTTGCCGTTTCATAACCTCTCCTTCCTGAAGAGACATGAATAGCTTGTGGTTTGATTGAGAGTACTTCTTTTAGTGCAAGATCTGCGTAGAGTTGTGTGAACTCATCTAAGGGCAGTTTTCGAGTTAAATCTTCACAACCAGGCATTAGTCGAATGTGCTGTATGCTTTCGATCGTTTCTGAGTATTCGCCTTCCCACTCGGTTTCTTCGGGAAAACCTGGTTCTGTTAAAACGATTGGAGTGTAGTCGACTAATTTTTCTGCTTTTAGATTTTCAAAACTTCGTGCGCAGAAGCCATTTGACCGGTAAGGTACAGACTCTTTTGCCATATGGACAATTACGCCCGATTTCCGTTCTTCAGGTTTAACTGGGTGGTTGCCTAATGTTGGAAAAGCTTCAAGGTCATTTAAACGGCCTTGTACGATGCTCAAAGCGTTTGGTTTAATCCATGCGTTTTTTAACTTGTGGTTTGCTAAAGCAACCGATTGAGATATATTTCCCCTTTTAACGGCACTTTGCTCCAAAAGAGCAATGAAGTCCTTATTCTGTCTATGTTTGGGAAACAGTGCTCGTCCCCAAAGGTAGGCTTCTTCATAGTTACCTTTGCCGAGTGCATTACGTATTACATTAGAGCCCGCAAAATTTGAGATATATGGTTTGCCAAGTAAAGCAGCAGCACCCGAGTTTTTTGAAACGAGGCCGACTTCAGCTGGAGCCTTAACGAGGATCCATAAGAGTTTTCGGAATCCTTCCCGTTTACTGACATCTCCATTGGCTAGTCTTTTCGATAGTTTTTTTAGGCGTTCAACTTTTGTCACTCGCTTAGTGGTTTGATTAGCTGTAGCTGACTTTTCAACGTAGCTGACGGCTGCTTTTTGATATTGAGTTAGCTTCTCTTGCATTTTCGTAATTTCTTCATGCGCGATGCCGAGGAGCTCAAGTGATTTTTCGAAAGAAGTATTTTGGTCAATGGCATCTGTAGCCCCTAACCATTCACCCCAGACTTTTCCTTTGTCCATTCGGAACCTTCCTAGATAATTGAACAGGGCTATTACTAATTTGAATCTTACCTTCTTAATGGAATTGGCTTTTTGTCATCCCAACGAGGTTGAAAATGGTACAATGCAATATTCTCAGTAGATCTAGAATCGTGAATCAAAGACTGTTTTTCAAGAAGGATATTTCGTTTAGCGTTGAATTATTCATTAGGGCAAGTAAATTTCCTTAATGAGTACAAGCAGTAAATGGATTCAGTGAGGTGCATCCTTAAACTCAAATTTCCAAGATCTGACTAAATGCTGAGTATCTTCGAGAGCTAAGAATGATGGAGATTTGTTTCATTTTAATCTGCAAACAGCAATGGACTCAGTCTGTCATCATCAAAGGACCTGTCTTGATGCGGGAAAGCTCAAAACAGAATGTCCAAGTAATGCGCTAAGAATAGTAGGGAAGCATTTAGTTTCTAGCTAACACTGACATCAATCAGAACTTTGGTGTATCGATTTGTTTAATTGATAAGCGAAACTTCTTAAATCCAATTGGTGCTATTGCAAAGGTCATTACTTTCCGAACAGCTAATGAGTGACGCTGAATTAGTTCCAAAGACCCTTGGTATCTACCACAATCTTATTTTCCAGTTTATCCTTATCGAGTGCTTTGAACTCCTTGTGATCCACGAGGAGAAGGACAACGTCTGCCTCTGCAATTGCACTCTCGTAGTCCTTTAGCTCGACGTTATCGAATCCCTTGAGTCGTTTAGGGAGTTCATGAATGTTAGGTTCAGCGATTAGGAACTGGATACCTTCGAGATCTTCCGCAATATCTACAGTGATGTTCAGCGCTGGAGATTCGCGGAGATCATCGATGTCTGCCTTGAACGCTAGGCCGAGTACTGCAACCTTAGTAGTTTCTTTTTGCGCGACAGCTTCTTTGACTTTACTGATTACCCACTGAGGCTTACCATCATTAACTTTGCGGGCGGTATGGATGAGCTTTGAGTTCTCAGGATCGGCGGAAACGATAAACCACGGATCAACTGCAATGCAGTGGCCGCCAACACCAGGGCCTGGCTGAAGGATATTCACGCGAGGGTGGTGGTTTGCGAGTTCGATAAGTTCCCACACGTTGATATCCAGGTTGTCAGCAATGAGAGACAACTCATTTGCAAAGGCAATGTTCACATCGCGGAAGGAGTTTTCCGTGAGTTTAGCCATTTCTGCAGTTACATCATTGGTCGGAAGTAGTTCTGCTTCGCAGAAGGTTGCGTACACAGCGGTTGCTCGTTTGGTAGCTTCTTCTGTCTGTCCACCAATGATGCGGTCGTTGGTTCGCAGTTCTTCCATGGCCTTTCCTGGAAGAATACGTTCAGGGCAATGTGCGAAGTAGATTACTGGTTTACCTTCTGGGTTTTCAGCACCATCGGCTACCAAATCTGGGCGTAACTCAAGGATCTTGTCGGCCATTTTCTTGGTCGTCAAAGGTGGAGAAGTTGACTCCAAAATGACAAGTTCGTTTCCTTCAAGTTTTGGTGCGATCGCTTCTGCCGCAGAGTAGATGTATTTCATATCTACGCTGTAGTCATCAGTGAATGGAGTAGGGACGGCGATGATGTAGGTCTGTGCGTGTACCTGGGTGGTAGTTGCACGGAAGTTTCCTGATTCGATGGCTTGCTTTAACTCTTCTTCCAAGCCTGGTTCAACAATAGTGACTTCACCACGATTGATGCGCTCCACGTTCTTTTCATTGACGTCAACACCGGTTACGTCAACTCCAGAGTTTGCCATTACTACTGCGGTGGGAAGGCCGATGTATCCTAGGCCGACGAATGCAACCGTTTGGTTTGTCATTTTGGAATCCTCAATGTTTGTGAGATCTGGGCAGCGATACTTTCATGAATAAGTAGTGATCTCTACCGTGTTCTACGGACTTTACTACTTGGATATGAATGTCGTATTCTTACCCTCAATTTTGCGCACTAGCAACTGAGGAAAAAGCTGAGATTTTGCTAAAAATTATTCCTGAAGAGCTGGAACTTACATGATTGGACATGTTGGTTCTAGCACGTAACCATCAGACTATGAGGTGTTTCGGTGCGCGTTGAGATAGTGCAGCACAGGTCTAGATGCGAAAGTCTGAAACTCTCAAGGCTAAATCTTGCTTCGGTGGGTAACTTTCATGCCACCTGTTAACATTTCTAGAGATTCGAACGTTAAGACAGCTATAGGTTTAATTAGATTTCGACTATCAACTGGAATCTACCTGACTGCAAATTAAGGATAGTGGCTGATGTACCAGATTTTTGAGCAGATTTTGTTCGCCATCAATGAGATTTTGGGCTACGGCCTTCACGCAGGTTCCTCTGCTTCAAGCAACCTGTCACACGGCCTCGGACTGTTCTGATCCGAGCAGTTGTTTCGCAAGAAGGCCCACGATTTGAACATCGTGGGCTTTCTCGTTCCCCCTATTTAGTGTGGATTGGTCTTTCTGTAGACCACGTGCACGACAAGACAATCCTAAACACGTATCCTTGAATGCGTGACTGAACATTATGATGTAGTAGTACTCGGAGCGGGCCCCGGTGGCTACGTCTCCGCCATCCGCGCGGCCCAGCTTGGCAAGAAGGTTGCCGTTATTGAGAAGCAGTATTGGGGCGGTGTCTGCCTTAACGTTGGCTGCATTCCTTCCAAGTCTCTGATCAAAAACGCTGAGGTTGCCCATACCTTTACCCATGAGAGGAAGACCTTTGGCATTAACGGTGAAGTGACTTTCAATTACGAGGATGCTCACAAGCGTTCCCGTGGTGTTTCCGACAAGATCGTCGGTGGAGTTCACTACCTGATGAAGAAGAACAAGATCACCGAAATCCACGGTCTTGGTAACTTCAAGGATGCTAAAACCATTGAGGTTACTGAGGGCAAGGACGCTGGTAAGACCATCACTTTCGATGACTGCATTATCGCAACCGGCTCGGTTGTCAATACCCTGCGTGGCGTCGAATTCTCTGAGAACGTGGTTTCTTATGAAGAGCAGATTCTTAACCCTGTTGCTCCAAAGAAAATGGTCATCGTTGGCGCCGGTGCAATCGGAATGGAATTCGCTTATGTTCTCGGTAACTATGGTGTAGACGTAACCGTCATTGAGTTCATGGATCGCGTTCTTCCAAACGAAGATGCTGAGGTCTCCAAGGTTATTGCTAAAGCATATAAGAAGATGGGCGTTAAGCTCCTTCCTGGCCACGCGACAACCGCAGTGCGTGACAATGGCGATTCTGTTGAGGTTGATTACCAGAAGAAGGGATCTGACAAGACTGAGACCCTCACTGTTGATCGAGTCATGGTTTCCGTCGGCTTCCGCCCACGTGTTGAGGGCTTCGGTCTGGAGAACACTGGTGTGAAGCTCACTGAGCGCGGCGCAATTGACATCGACGATTACATGCGCACCAACGTTCCTGGCATCTACGCTATCGGTGACGTCACCGCTAAGCTGCAGCTTGCTCACGTCGCAGAAGCACAGGGCATTGTTGCTGCTGAGACCATCGCTGGTGCAGAGACCCAGACCCTTGGTGATTACATGATGATGCCTCGCGCAACGTTCTGTAACCCACAGGTTGCTTCCTTCGGTTACACCGAGGAGCAGGCTAAGCAGAAGTGGCCTGATCGTGAGATCAAGGTTGCGTCCTTCCCATTCTCTGCAAACGGTAAGGCAGTCGGCCTGGCTGAGACCGATGGCTTCGCAAAGATCGTTGCGGATGCTGAATTCGGTGAGCTGCTCGGTGGACACCTCGTTGGTGCTAACGCTTCCGAGCTCATCAACGAACTGGTTCTGGCACAGAACTGGGATCTCACCACTGAAGAGATCTCACGCAGCGTTCACATTCACCCAACGCTGTCTGAAGCTGTTAAGGAAGCCGCTCACGGTATTTCCGGACACATGATCAACTTTTAGTTCGAAGATTCAAAAGGCCCTGATTGTAAGTGCAATCGGGGCTTTTGCCTTTGGTCTTCCAAATTTATAGCTAACTTTTTATTAAGTGTTCATGTTCACATAAACTAACCCGCTGTCAAGAAGAATTATTCTAAAAAGTCGGTATCGTCATGGCCTATGAGTTTGCCAATCGATGAGCATCAAAATGCTGTAAGAACTGTTGTTGTACCTGCCGCTGGAATGGGCACACGCTTCCTTCCCGCTACCAAGACGATCCCCAAGGAGCTTCTCCCTGTGGTTGATACTCCGGGTATTGAGCTTGTTGCTAAAGAAGCTGCGGATCTCGGTGCATCTCGACTGGCTATTATTACCGCGCCAAACAAGGACGGAATCCTTAAGCACTTTGAGCCTTTTCCTGAGCTTGAGGCAACTTTGGAGGCTCGTGGCAAGACAGATCAGCTGAACAAAGTTCGGGCAGCCAGGGAGCTAATTGATACGGTTCCCGTGGTTCAGGAAAAGCCACTGGGACTTGGTCATGCAGTGGGTCTTGCGGAGTCTGTGCTTGGTGAGGACGAAGATGTTGTTGCAGTCATGCTGCCGGATGACTTGGTGTTGCCTTTTGGCGTGACTGAAAGGATGGCTGAAGTTCGCGCTAAGTTTGGCGGATCAGTTCTTGCTGCTATTGAAGTGGCTGAGGATGAAGTCTCCAGCTATGGCATTTTTGAGCTTGGTGATCTTGATGCGGAGTCGGAAAGCGAAGACATTCGACGTGTCGCAGGAATGGTTGAAAAGCCTGCGCCTGAACATGCTCCATCAAGGTTTGCGGCTACTGGCCGCTATCTTCTTGATCGCGCGATTTTTGATGCGATTCGTCGAATTGAACCTGGTGCCGGTGGGGAACTGCAGTTAACAGATGCCATTGCATTGTTGATTGAAGAAGGCCACCCAGTCCACATTGTGGTTCATGAAGGAAAGCGCCATGATCTCGGAAACCCAGCTGGCTACATCCCGGCTGTTGTGTACTTCGGGCTTCGCCACGCGGAGTACGGTTCCAGAATTCACCGTGCGGTGAAGGAAATTCTCGCTGAGTTTGAATCTTAAAAAGCAGAAGCTACTTTCCATAGACACAATGTGGAAGGCGGTTTTTGCATGCAGCTAAAATCTGGTTTCATGGCTAAGAAAGTTGATACCTCGAACGCTACTCCTGCGCTTGCTCTGCTTACGGAGAAACAGATTCCCTTTGAATTGGATGTTCATGACGTGGATCCGAAGTCATCAAAGGGTTTTGCTTTGGATGCTTCCGAAGTGATGGGTGTGGAGCCGGAAGTAGTGTTTAAGACGTTGATGGCGGACATCGACGGTGAGCATGTTGTAGCGATTGTTCCCGCTAGCAGCACGCTGAATCTTAAACAGTTGGCTAAAGCTGGAAAAGGTAAGCACGCCAACATGATGGACCGTAGCCGCGCGCAGGTTGTTACTGGTTATGTCCCGGGTGGAATCTCGCCAATCGGTCAGAAGAATAAGCATCGCGTGTTTTTGGATGAATCTGCGATTCTCCAGGATCGGATCTATGTAAGTGCAGGGCGCAGGGGATGGTCACTGATTATTGCCCCAGATGATGTTTTGCTTGCAACTGACGGGGTTTACGCGGATATCGCTGACCATTCTTAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP010451|351938:446240|400440_401082_-|WP_038582347.1|DBSCAN-SWA
MLPNRLFLRLFALIALIGVITGGILLLINSQSSKQTSSSTRTTVNNSMAIRALQREEEIVLLSAGALGIHEKTVERTIRGKRIPGTQKTVHVQYSYTGKLGIDASDVEIKSAGDNKLSITIPEFIFIGYDDLKFKTIAEDDGWISFSTDDIDTAEVVSEIMSQENFVEQVTTNREMLEDQAVDFYNDLLHEFTEKLDTDRYEDTKIELEFEFE
>NZ_CP010451|351938:446240|418005_418224_-|WP_040966890.1|DBSCAN-SWA
MTVVLAPEFDIALNCGIGAGVVIFGNEAVKDTSAGVALFSGAFLIVFEPAIDDDVESVECFNTWAFSGCGWC
>NZ_CP010451|351938:446240|381587_382238_-|WP_040966868.1|DBSCAN-SWA
MYMSRMYLNPQRRQTRELLANPQKLHAAVLSSFPPSSSETTDEGRVLWRVDQTRESVALYVVSPAIPSFEHLQEQAGWSQEQSWQSSDYTAMLNRIVKGQKYAFRLTANPVHTVTEDGVKRRKAHLTPAHQLDWLTDREEQLGASFTGEAGEITAITTKSERRVFRREKRTVTIQQVTFEGSLEVKDANKLREVLCNGIGKARGYGCGLLTLAPME
>NZ_CP010451|351938:446240|422572_422824_+|WP_052461394.1|DBSCAN-SWA
MVPEPVATTLTGLNTTLFTQCQDLGLQPHWRKQQPIIELFSEDVAACLAFPGVGFDPVRYESRKADKTGTITVEDNLGPTPGK
>NZ_CP010451|351938:446240|409103_409580_-|WP_040966885.1|DBSCAN-SWA
MKALIKPLVSTALSLSIIFAGTQGIAHAQSSFVSGSSSVETNINQDAKSLRYTELYKKVFLALGHELNPLAQAKADDLLQRALRGELVFENGSYVEQNSPGIHYASVDQISSDDLDFELSLLEIVYADLEIYPNEDLIQIGVASGKDRQYYYIVHVAL
>NZ_CP010451|351938:446240|436005_436299_+|WP_040966891.1|transposase|DBSCAN-SWA
MPRKTYTEEFKRDAVALYENSPGTSIQTIATDLGVNRATLANWVKKYGTAAPTEKPSPASVNEAERIRKLEREVRKLREERDILRKAAKYFAEETNW
>NZ_CP010451|351938:446240|418720_419485_+|WP_077313832.1|transposase|DBSCAN-SWA
MSDAILGARVKTVFTAEHGCYGAKRITAELKDQADQAPVNHKRVARVMRELKLFGYTKKRKVTTTVSDQKKPVFPDLVGRKFTAEKPNQLYVGDITYLPIADGSNMYLATVIDCYSRRLIGFSIADHMRTSLVQDALLMAKGQRGSLTGAIFHSDHGSVYTAHAFQNTCKELGMRQSMGSIGTSADNALAESFNAAMKREVLQDSKTFMNQLICRRDVFRWCTRYNTVRRHSWCKYLAPAVFEKRGSVILKSAS
>NZ_CP010451|351938:446240|423771_423966_-|WP_080770709.1|transposase|DBSCAN-SWA
MQQIANDLGINRVTLKNWIIKYGSNHNAQGTTPSVAVSEAKQIRQLKKENALQRARTRHPAQSC
>NZ_CP010451|351938:446240|422280_422481_-|WP_052461393.1|DBSCAN-SWA
MQLECGKQLRLNNRGAGTSPDAGGVIEDQLAGYATDVFEDGAQSVTNAFRGFPAIGVPNGYFEAPW
>NZ_CP010451|351938:446240|359451_360387_+|WP_038582304.1|DBSCAN-SWA
MRTVVTGGAGFIGSHLVDLLIKEGHEVVVIDNLSRGRLENLSDAEATGKLTFVEADLLDVDFNEFLGTHKPEVIFHLAAQIDVRHSVVDPLHDAETNILSTIRIADAARQHGVRKVVFTSSGGSIYGEPSEFPVDETVPVDPHSPYAASKVSGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFALRLLGGLDTKVFGDGGNTRDYVYVGDVVRAFYLASGEIGGGERFNIGTSVETSDRQLHTLVAAAAGSKDDPEYAPARLGDVPRSALSFGKAKEVLGWEPEVNIEQGVAKTVEYFRTH
>NZ_CP010451|351938:446240|434915_435776_-|WP_080770711.1|transposase|DBSCAN-SWA
MSRLLQVSRSGYYKWAKAQATRLRGEDTRQEFLDQLDKRIHDIWEDSGEVYGAPRITAELVDEGIIVNRKTVAKRMRLMGIEGVSPRAFVPVTTIQSKRKSTLPDLVKRLFDQGQLNRVWMSDITYLRTGEGWLYLCVIRDGHSRRVLGWAMDSVQDSHLVERALRMAHTLRGDVPEGLVFHADRGTQFTSEQLWQVCQELGIAQSVGRTGVCFDNAMSESFWSTRKTEFYDRKKWPTRDEARKAAARWIEIVYNRRRRHSAIGMISPVDFEARIAEQDDRKKVAA
>NZ_CP010451|351938:446240|425395_425656_+|WP_040966894.1|DBSCAN-SWA
MTISIPTTAKDQLCFPSDEQVLLTEAMDLLTCIESSLRVADVDTQMAVARLAELYLGADDGDHFQTVLAKITQLRDRIYIQVDQAD
>NZ_CP010451|351938:446240|441238_442492_-|WP_040966903.1|DBSCAN-SWA
MTNQTVAFVGLGYIGLPTAVVMANSGVDVTGVDVNEKNVERINRGEVTIVEPGLEEELKQAIESGNFRATTTQVHAQTYIIAVPTPFTDDYSVDMKYIYSAAEAIAPKLEGNELVILESTSPPLTTKKMADKILELRPDLVADGAENPEGKPVIYFAHCPERILPGKAMEELRTNDRIIGGQTEEATKRATAVYATFCEAELLPTNDVTAEMAKLTENSFRDVNIAFANELSLIADNLDINVWELIELANHHPRVNILQPGPGVGGHCIAVDPWFIVSADPENSKLIHTARKVNDGKPQWVISKVKEAVAQKETTKVAVLGLAFKADIDDLRESPALNITVDIAEDLEGIQFLIAEPNIHELPKRLKGFDNVELKDYESAIAEADVVLLLVDHKEFKALDKDKLENKIVVDTKGLWN
>NZ_CP010451|351938:446240|356774_357410_+|WP_003863266.1|DBSCAN-SWA
MAHDGLRVENIVTSGIFALDGGEWEVDNNIWVVGNDDEVFIIDAAHTAAPIIEAVGGRTVKGILCTHAHNDHITVAPELAKEFDAPIFVHPGDQMLWEETHGNLAHEDLADQQKFQIAGTELIVLNTPGHSPGSSCFYLPEANELFSGDTLFQGGPGATGRKYSSFDTIIESLKTSILDLPAETTVRTGHGDHTSVGAEAPHLEEWIKRGH
>NZ_CP010451|351938:446240|403938_405954_-|WP_040966881.1|DBSCAN-SWA
MTDYTFLEDIDTPEALAWAKKWSGESVEKLKSPAKDALEARLLAALDTDDRIAYVSRRGEKLYNFWRDAQHPRGVWRTTTLESYYSAQPKWDVLIDVDALAEAEGENWVWKGAVVRSPERDLALVKLSRGGADATVIREFDLATREFVGAGAFELPEAKSSVTWIDADTLLVGTDTGEGSLTDSGYPARAVTWKRGTPIEQASVFFEGAREDVATHAWRDSTPGFERIFASRSLDFYNSETYLETADGLVLLEVPTDCDVIVKNQWLFVNPRTDYAGIPAGGLGVLELDAFLDGARDFNQVFTPSASTSLQGLATTKNFLVLTLLNNVSTEIVSVPLSDPVAEPTRMELPDHVTAHVVATSPLDGDEIWVQAASFTEAPTLLRAELPGALEAVKKAPLQFENAGQETRQHWATSADGTKIPYFITGNFAGTSAAQRKTLVHAYGGFEVSLTPSHSPTRGIAWLEKGYYFVEANLRGGGEFGPEWHSQATKLNRMKVWEDHRAVLADLVERGYATPEQIAIRGGSNGGLLTSGALTQYPEAFGAAVVQVPLADMLRYHTWSAGASWMAEYGNPDDPEERAVIEQYSPVQAVVGVEKRIYPPALVTTSTRDDRVHPAHARLFAQALLDAGQAVDYYENTEGGHAGAADNKQTAFVESLIYTWIEKTLDQQGSI
>NZ_CP010451|351938:446240|407136_407637_-|WP_040966883.1|DBSCAN-SWA
MQNITRKIAAIAIAGTLILPATTGVAHAQSNFSAGSSSFDFGSSGPEEPQVEPLEVRLEVAYERLIAANGHVLHADQELEATGLLNRAFAGEFEFVDGKFYVYDEEKLTEYWIDLLTEEQAEEILDNIEADIKWAEENPEDSDKEFGLEVGKLGNYFYIAGVETYV
>NZ_CP010451|351938:446240|380601_381582_-|WP_040966867.1|DBSCAN-SWA
MQSGMPPSTPMQLSRATDRISFLYLEHCTLGRDGGALTATDDKGVVHVPVAALSVLLLGPGTRLTHQAVSVVADSGCSIVWVGEEGVRYYAHGRSIARSDRLLVKQAEKVSNTRSRLAVARAMYDMRFPNEDTSSLTMQQLRGKEGARVRKIYRQNSEEYGVDWNRRMYDPDDFLSGDPINQALSAAHTCLYGLCHSVIVSLGCSPGLGFVHTGHDRSFVYDIADLYKAELSIPVAFQVVSDLNKNGRAEMSDVSSITRRAMRDAFKQLRLAERVAADLKTLLIDEETVSSEEFWADIVQLWDGNDRRVSGGTNYGDPVHFPESEK
>NZ_CP010451|351938:446240|437610_438765_-|WP_080770713.1|DBSCAN-SWA
MKSNLIGWTPQASPPLTEAIHSLPYAQGEKKILLAYTPVARMNPYQALLYSSCNSYGIAPTELIPFNTFSKVDKLKNLADEVVIHFHWINSILATALDAEEAKRRVKETRTELDRLKNQGIKFAFTLHNKLSHDAKFIDAEIELQQTIINHCDVVHSMSRAAISSMREFASIPQEKTIYAPHPTYRNVYPDFLPKAECRKSLGIRPEEFVISLFGAIKPYKGLKMLMEQWREIAASSDVPLRLLVAGDADGSIEANDFINWATLEPSVTIHPQKVPFEQVQLFVKSADAGIIPYGRTLNSGAALLHLTFGNPIITVNEPALVEGVPPSLFETFNDADDLAYAISNALSRFTAPNLDADLLSLELERAPRIVSNEFSKNLVAKIS
>NZ_CP010451|351938:446240|432550_433756_-|WP_040966899.1|transposase|DBSCAN-SWA
MTTGTVDVTMGLDVGKTAHYACAMLNSGEIIYDKPLPQDEDQLRKVFTDLQDHGTVLMVVDQPNTIGALPIAVARDAGCLVGYLPGLAMRKAADLYPGRSKTDRQDAFIIADTARTMPHTLRAVDRENEVLSALKMLAGFDDDIAKDATRTINRLRSVLTQIHPSFERALVGDIITRPLVLEMLIHYGGPTKMKKAGYHRVLGWMTNRAKKDPTKLVDAIFEGLKAQTVTVPGTAAAEIVIPQLATNIKALLEQRKTIAEQVEELLEEFPLHHVLMSMPGVGIKTAANILLAVGDCSDFRSAGHLAAYAGIAPVTRRSGTSIRGEFPARSGNKRLKNALFYSAFASIRFHEPSKTYYERKRAEGKRHNAAIMCLARRRCNVIYAMLTRAEFFREVPARAAT
>NZ_CP010451|351938:446240|429696_431577_+|WP_040966898.1|DBSCAN-SWA
MNIKKSVKAARTGFWHLRQGGLPQLWKWAVPRLVAKGMMAPSLGPWDVKSVQDYVPLELTKSYGHLKVAAILDDFSLAAWGGEFDLLQVRPSTWQEQLEEQNIDLLLVESAWNGNHGAWQYKLTGPNAPGPELVDLVKYCRKNSIPTVFWNKEDPPHFEDFLTTAKLFDAVFTSDSNRIAAYEEELGHDRIQSMAFAAAPAIHNPVRGSWLHQEGDVAFAGMYFAHKFTERRQQMELLLDAAVQVGPRMAHGLTIFSRFQGHDERYQFPALFDRFVVGSLPYQKMLTAYRGFKVFLNVNSVVESPSMCARRIFEITASGTPVITTPSKAISNFFPPEEVTVVETHEQAQLAMRALVNSPQLRDRMVHKAQRRIWREHTYSHRASQVLEAAGIDHEKSSLPTVSVMVSTNRPHQIEHVLTQVAHQQQVEMELLLLCHGFEPKHDMISRRCVELGIQNYKILEGPASWSLGACLNKIVEESSGQVLAKFDDDDFYGPNYLLDQLNALNYSGAGLVGKECSYLYDAETDVIIRRRPEREHIFTRFVAGPTLVGFAEVFRAHPFADRSTGEDTEFLRDLVEGDVKIYAADRFNFLQMRNKTGHTWSVSGAELLANGVVEVIGLHIDQVIC
>NZ_CP010451|351938:446240|437098_437425_-|WP_080770712.1|transposase|DBSCAN-SWA
MFIVSSSRKKYTPEYRQEAARLVIESGRPIAHVAKEIGVAEGILGKWVKLERERQGSDDGRSDADRARPPDSRHGGFNQEADFRITEPRFSNTAGARYLHQECRRTVL
>NZ_CP010451|351938:446240|444746_445670_+|WP_040966905.1|DBSCAN-SWA
MSLPIDEHQNAVRTVVVPAAGMGTRFLPATKTIPKELLPVVDTPGIELVAKEAADLGASRLAIITAPNKDGILKHFEPFPELEATLEARGKTDQLNKVRAARELIDTVPVVQEKPLGLGHAVGLAESVLGEDEDVVAVMLPDDLVLPFGVTERMAEVRAKFGGSVLAAIEVAEDEVSSYGIFELGDLDAESESEDIRRVAGMVEKPAPEHAPSRFAATGRYLLDRAIFDAIRRIEPGAGGELQLTDAIALLIEEGHPVHIVVHEGKRHDLGNPAGYIPAVVYFGLRHAEYGSRIHRAVKEILAEFES
>NZ_CP010451|351938:446240|427966_429694_+|WP_040966897.1|DBSCAN-SWA
MNEAQHVFHEFKGFLSRNARELRTGVWHYRNGGIQQLKLWRWNQAAQQPTASRKAKLTEGGLRRDFPGLRDAWSKKSGQDKEWAAASETYNYRNVFAQGWILATRVKDLNLPPSWVEISFGEKYFTCDPALKVVDKGKSDQLNQLLVLGQATDSEKKLRSSQEVAQELYSILENKRQPWIEFDEAVTWLGGRFVVIARHGAETRVHVDAMASRSCYWGTSDTEEVVLASHSALVAESVGDFSSTRARWVLNHPEYHNPAGVYLPGTITPFDRAQLVFANCYLSINDNAVQHNRFFPPSENNPVSVLSVEAATEAYLAEVRFQMDVILSWEPRSVFALTSGSDSRAILNASLDLLQKAKSTAMTYHFFEKDADHTRKDLLGANRLAERSGLKHRILNLKPWDPAARFAKLYTKTFPVWARFGALARACYEGLSAKETLIIGVGGEIGTAFYLERNSATVTPEVLAAKFTQDSFQHDPKLIAEFENYMAYSQLDSEHTGSLDLYDLFYWEHRMSSWAAYWYSELDFGPTVALPLNSRRVFCAMLGVPLEDRVRKSVYGTLDSWANTIAENLSSGGDN
>NZ_CP010451|351938:446240|433995_434355_-|WP_080770710.1|transposase|DBSCAN-SWA
MSDALLGARVKAVFTAEKGCYGAKRITAELKDQTGHEPVNHKRVARVMRELKLFGYTKKRKVITTASDQKKPVFPDLVGRKFTADKPNQIYVGDITYLPIADGSNMYLATVIDCYSPLL
>NZ_CP010451|351938:446240|418298_418592_+|WP_040966891.1|transposase|DBSCAN-SWA
MPRKTYTEEFKRDAVALYENSPGTSIQTIATDLGVNRATLANWVKKYGTAAPTEKPSPASVNEAERIRKLEREVRKLREERDILRKAAKYFAEETNW
>NZ_CP010451|351938:446240|382238_382937_-|WP_040966869.1|DBSCAN-SWA
MPTLLLRLSGPMQSWGVSGRFVNRSTSSSPTKSGVIGLLAAAEGRPREQSVADLVNLRFGVRTDQVGSVLRDFQTEIDWRTNKAKPLTNRYYLQDYRFLAAIEGPQEILEGLETALKNPVFPLYLGRRSCPPGERVPLKIVNENLEIALQKSDWLAADWYRKKASTSVRLPISRDLLPGESADELIRDLPESFDPKERRYELRPIKHDSVTISNEVGKKPIDHDPFSLIGGV
>NZ_CP010451|351938:446240|410141_411353_+|WP_040966886.1|DBSCAN-SWA
MTVFIGHTRFSVLDPSSPNWQITQSGRFKDIDEYREYLFSPERLELRTDIFLNYSLPELSKAAEKHRIVHIISYSDLLPDPWKSKLEKAIENYDFLIGDLRRSGGAILDPHMVAEEALGGNGIYGLYRLDDDDILSSTFFSNSAKYLKEEFAGMQVSFSDGYTGFWQNNFIRNVRKVHWPMLAIGFMNICSIKEGKIVSQPRPAPHHIADRTNAVIIDPRHPSYLWLRHEDQDTANKFSSSQIRQEIFRDMEKYKPVAVDFSFDPVFPAIAKSISMHRQYSLMSEELVLVSPSEFLLPKEMNWFELIVELDCGKGIKQHNALISFTIRDSDGDLVTEPIEGVPFSNDPKIKHYRYLKTELGESISNVEIQLPEGLTCNELRVQRFLNVESEIRVKNAKVRELT
>NZ_CP010451|351938:446240|351938_353120_+|WP_040966803.1|transposase|DBSCAN-SWA
MDEQRAFDQGLKEENTLITDLTTCARLSHNKALRLIKLSKSTAYYRNKPRPCPAPKPVLQAVAAPTAPGVELAAPGVEPTPEPWQGKEPAVSSVRQALAEHERQFIVDAITAYPQLSVSGVFNMLFNKGIYRASLRTWWRVAKQHKLLHKDRVNALSPVKRSPTPRVKPRLEATQPGQVVCWDVTFLPSLVRGKTYALHLAIDLFSRKIVGAKVAPTENTSTAVELLTQVLADNPGVVTVHSDNGSAMTSTRVRRLLADHGVALSLIRPRVSDDNAFVESVFHTLKYRPFYPKVFASMDQARVWVEEFVVYYNTVHPHSGVAGHTPQSVFDGSWRAVHRLRVQALDAHYRQFPQRYVGQPVVQEVAGVVRLNGARDDGSVQERVGGVASLLSA
>NZ_CP010451|351938:446240|401291_402551_-|WP_040966879.1|DBSCAN-SWA
MRYLTLATIIAGLSGFVVIIIAAWALGDSSQLSEEFTAYWGLFFAGTGVLTGLTQETTRAVTAGRARSGAAGVSGLPGASVGFRPFLFSFVVAAIVLVVLGASAPLWIGQLLSKLQGVGVGLLAVGLASYAIQATISGILSGCQLWKEYASLISLDTGIRMVLAVVAWLLGYQLLAFLIITVVGSISWLVIVLCFGSVRSVLGSVADVPRGVFIRQALLAMAASGATAVLITGFPTLLKFTNPSAVAGGVSMAAISYAVILTRAPLLVPLQQFQSAIIVRFVKGTSGPLKTLAGPLAIVWAVGLVGAGLAWLVGPWILDVVLQKELFAVPGWLLAMLTLGATTTASLMVSGCAAIAFERHGIYLTGWVVATVVAVGFLLGPFDLGVAAGLALIVGPLCGLLVHMGAFIGGDRKRVLTAG
>NZ_CP010451|351938:446240|395653_397009_-|WP_074508533.1|DBSCAN-SWA
MMFNKELTSRDTDIEGLLVFDFPVHGDNRGWFKENWQRTKMTSLGLPDFGPVQNNMSFNATAGTTRGMHAEPWDKFVSVAVGSVFGAWVDLREGSSTYGNVVTQKITPDVGVYVPRGVANGFQALEDGTLYTYLVNDHWSPDAHYANVNLNMIDWPLPITEISEKDKKHPALIDATPLPARQVLVVGAGGQLGTALRAQFPDAEFVTREELDITSDLTEARAWKQYSTIINAAAYTAVDQAEHDRAAAWDINAAAVANLATIARDNNLTLVHVSSDYVFDGTAESYDENAPFSPLGVYGQSKAAGDIAATTAPRHYIVRTSWVIGDGNNFVRTMKSLDERGIAPSVVDDQIGRLSFTEDIAAGIAHLLNVGAAYGTYNLTNTGEPASWADIARAVFSDPSKVTGVSTAEYFADKDAAPRPLNSVLKLGKIEATGFSAPTWQTRLNNYLKEL
>NZ_CP010451|351938:446240|406653_406959_+|WP_040968130.1|DBSCAN-SWA
MTVPEKLPEQLSEQVSDQPQQRNYVVIAALTLAVVGFVLACTPSAVLVGLIALVIAFFIAIISLCIPGWPKRQGVYALVLSVVGFAVGVVKIMVILEDMMS
>NZ_CP010451|351938:446240|411599_412691_-|WP_040966887.1|DBSCAN-SWA
MKLLRRIAAPAIALGIAMSTIIMPSTAGAAEVTPADVAGDTALSTISDSAPADEASAPRWRTYVNEADERVKEMWAYSPSMDRDIPLVVITADESAGPRPVIYLLNGGDGGEGAANWVMQTDALDYYLDKNVNVVIPMEGKFSYYTDWEEENESLGGKQMWETFLVKELPGPLEEKLNADGHRAIAGMSMSATTSLIFPQHYPGFYDAAASFSGCAATSSLLPWEYLKLTLDRGNATPEQMWGPRGGEYNIYNDALINSDKLRGTELYVSNASGLAGKWESVDSPRFEGLNQQVQSVAMAETVLTGGIIEAATNKCTHDLKAKLDSAGIAADWNLRPTGTHSWGWWQDDLRGSWDTFARAFGI
>NZ_CP010451|351938:446240|445718_446240_+|WP_074508513.1|tRNA|DBSCAN-SWA
MQLKSGFMAKKVDTSNATPALALLTEKQIPFELDVHDVDPKSSKGFALDASEVMGVEPEVVFKTLMADIDGEHVVAIVPASSTLNLKQLAKAGKGKHANMMDRSRAQVVTGYVPGGISPIGQKNKHRVFLDESAILQDRIYVSAGRRGWSLIIAPDDVLLATDGVYADIADHS
>NZ_CP010451|351938:446240|392994_394308_-|WP_003863255.1|DBSCAN-SWA
MSVQNPAIVSATPDTTISNTISTSEISKKDLKNAVRASFIGTFVEWFDYAAYMYMASIIAGVFFPELTGRAALVNTFALFALSFLIRPIGAVAWGHIGDRLGRTKSLSASILFMSLATFCIALLPGYNSIGIVAPILLLVLRLIQGFSASGEYAAAATYISESAPQNRRGLFASVVPAATACGLLLGSLFAALLTSLLDDASLASWGWRLPFLLAAPLGIVGLIIRRMAPETHVADEDSAKKLPILEVFKYPRALLVAFSGAILNAIGFYMVLAYLPTYLSEELGMSSSSAFIATTISSAVYAVLVVATGALSDRLGRRTTMLMAAALFAVFSIPAFLALDSASFAGIILIQVGMGAFLALNDGVLPSFISEQFPPDVRLTGFALTFNCANAFFGGTAAMIATWMIGASGNVIAPAYYMVAAAIITAIGVTFAAKSK
>NZ_CP010451|351938:446240|398062_398644_-|WP_040966877.1|DBSCAN-SWA
MSLSVVEAITNRRATRKYTDEAPTPELIDKIVDLALEAPSAFNAQQREIVVITDPAQKQKLYEASNQKQFLTAPVTFITVARVENEPEDLEEILGAERAERVAGFINGRSIQQAREATLRDASLAAAFLILAAQAEGLSTSPTTGWDEEKVKEAIGIGGRDDRAIALVIAAGFPNEQPEHPGRLQNRRIDNSY
>NZ_CP010451|351938:446240|384076_384697_-|WP_052461388.1|DBSCAN-SWA
MSEKTSVSNRSAVVSHVAKKLHELEAHLSAGTSRSKADLAKLRRAVGKAPGAIPDVWGITLEDLPEQLVGKTDAPSWGETSVHNALALFALHQQGKGDSMNQRGEGLGRAVRQYILTKDPGGGFDNESPILRRFNALSTSDSVDELLWHLRNTITQLRASNVKLDFAELAGQLYDFHIPEARDRVRLAWGRQLYTAPKTTEKASES
>NZ_CP010451|351938:446240|355667_356774_+|WP_003863269.1|DBSCAN-SWA
MSTVVPGIVALSKGAPVEKVNVVVPDPGANDVIVKIQACGVCHTDLAYRDGDISDEFPYLLGHEAAGIVEEVGESVTHVEVGDFVILNWRAVCGECRACKKGEPKYCFNTHNASKKMTLEDGTELSPALGIGAFLEKTLVHEGQCTKVNPEEDPAAAGLLGCGIMAGLGAAVNTGDIKRGESVAVFGLGGVGMAAIAGAKIAGASKIIAVDIDEKKLEWAKEFGATHTINSSGLGGEGDASEVVAKVRELTDGFGTDVSIDAVGIMPTWQQAFYSRDHAGRMVMVGVPNLTSRVDVPAIDFYGRGGSVRPAWYGDCLPERDFPTYVDLHLQGRFPLDKFVSERIGLDDVEEAFNTMKAGDVLRSVVEI
>NZ_CP010451|351938:446240|362003_363026_+|WP_040966863.1|DBSCAN-SWA
MKSIDLEQLAGTQSRTYQSRKITDEMVARPVHVAIALWEVPWESAKSGKIEGWVIAVDSPRGRFVRSGQTKNGDAVNRTVSMLKSALKGVRGKAWIVTGRRQAALRAALVRENYLVTGSFAEQNRAGVKASAISRRAEQSALYKAKKIGEFAERAPRVKERQEAHWWPRLSRTQGTAGVLRLATDASTDGVFRGAMCFVASNGDYLLETQDTTASSDELELESITHALIYLKTIGATQAIIESDSKAALEAIDFILNTRPRRGRWRGITARARNRFRDAWEALIDDCVVELSRVLGHAGDPLNQAADQIAYMGMRAVIFEQKSAHPTLLKGIDKALRKAE
>NZ_CP010451|351938:446240|425804_426077_-|WP_040966895.1|DBSCAN-SWA
MRPLTLKRHRDTWPTTGMVLILALGTCLMIMGVFNLATDVLFGLGLTTLGIGLFIPGVWWIRWYQKPQLLGRLLPISIIFIILGMIGIAL
>NZ_CP010451|351938:446240|422876_423224_-|WP_080770708.1|integrase,transposase|DBSCAN-SWA
MRTSLVQDALLMAKGQRGSLMGPVFHSDHGSVYTSQAFQDTCKKLGVRQSMGAVGTSADNSLAESFNAALKREVLQDSKTFANQLVCRREAFRWFDLVQHKSQAFLVWLSRTNGV
>NZ_CP010451|351938:446240|436427_437192_+|WP_077313832.1|transposase|DBSCAN-SWA
MSDAILGARVKTVFTAEHGCYGAKRITAELKDQADQAPVNHKRVARVMRELKLFGYTKKRKVTTTVSDQKKPVFPDLVGRKFTAEKPNQLYVGDITYLPIADGSNMYLATVIDCYSRRLIGFSIADHMRTSLVQDALLMAKGQRGSLTGAIFHSDHGSVYTAHAFQNTCKELGMRQSMGSIGTSADNALAESFNAAMKREVLQDSKTFMNQLICRRDVFRWCTRYNTVRRHSWCKYLAPAVFEKRGSVILKSAS
>NZ_CP010451|351938:446240|390754_391816_-|WP_040966873.1|DBSCAN-SWA
MSIQVKALQKTGPEAPFEVKIIERREPRADDVVIDIKAAGICHSDIHTIRNEWGEAHFPLTVGHEIAGVVSAVGSDVTKWKVGDRVGVGCLVNSCGECEQCVAGFENNCLRGNVGTYNSDDVDGTITQGGYAEKVVVNERFLCSIPEELDFDVAAPLLCAGITTYSPIARWNVKEGDKVAVMGLGGLGHMGVQIAAAKGADVTVLSRSLRKAELAKELGAARTLATSDEDFFTEHAGEFDFILNTISASIPVDKYLSLLKPHGVMAVVGLPPEKQPLSFGALIGGGKVLTGSNIGGIPETQEMLDFCAKHGLGAMIETVGVNDVDAAYDRVVAGDVQFRVVIDTASFAEVEAV
>NZ_CP010451|351938:446240|414626_415922_+|WP_040966889.1|DBSCAN-SWA
MRILVLSQYWYPENGVPQRRWSWLSKLLIREGHEVVVICPPPHYEREVSVGSWLRSVIKRKPSSIETGPSGEKIVRSGYFPTGQSITMKAFNQGAVALAMLWRGSFHGRTLRDFKPDLVIGTVPAIPTSLITPLIAKRFGSPYVIDLRDTWPELLNEGRKWNSAVGAQSIRQKILSNGPLQVMGVIVRRLMYRSFKASAGLIFTSNSHAAWLSKTMQMKGKTLVTATIRNVFPPKSDAVRASQGIENEATLHVLYAGTLGRAQNLNNVLEAAKISRDKGIPVELRFVGAGATSNELRRKIAKENLHAEVVGRVQASELANHYTWADTALVHLTDWSALDHAVPSKTYELMANGIHITGVVKGETASLIKELNCGVVVDPEDPEALASSWGKLLNDRSQLQVSDTAREWVITQRDEIVPQELYAFLSELGIQ
>NZ_CP010451|351938:446240|426079_426892_-|WP_052461395.1|DBSCAN-SWA
MSVESTIDYSSPTVFVRNVSKTYRSHGRRGTEVRAVSDVSLVSYAGQAIGILGHNGSGKSTLLRMISGGDATSSGEIMVSSQPSLLGVSAALQPNLTGAANVRLGCLAMGMSPEQADELYGEIIDFAELGDAINRPMNTYSSGMGARLRFAISTSIKPDILLIDEALSTGDATFAKKAKDRMGELLGRSGTVFLVAHGGGVIRENCNHAIWMHQGEIIGDGDLESIAQPYDVWGERKASQKTKEADKIIDQMKSYYLPPKLLLSSEVNED
>NZ_CP010451|351938:446240|394789_395653_-|WP_040966874.1|DBSCAN-SWA
MKGIILAGGSGTRLYPITKGISKQLMPIYDKPMVYYPLTTLIQAGIKDILIITTPEDSASFERLLGDGSSWGINLTYAVQPSPDGLAQAFIIGEEFIGDDDVALVLGDNIFDGAQLGRALKQCSSPDGGIVFAYEVSDPERYGVVEFDAANKAVSIEEKPTAPKSNFAVVGLYFYDNRVVDIAKSIKPSSRGELEITSVNDAYLQQGALTVQRLDRGDVWLDTGTIDSMSEASSYVEVLQKRTGNIIGSPEVAAYREGFITSSELVVLGEELKKSGYGNYLMRVAGE
>NZ_CP010451|351938:446240|402550_403933_-|WP_040966880.1|DBSCAN-SWA
MIMRRLRSTPVPGTRDSYTGIDFNLGFHIRRYELDLTYRVAPNLLMGTATLHMDNYRALDALTLDLGGSLRVEKVTAKGTAGTHIQVARFRHAGRKLRITFRKQIPVDQEFSLTIRYRGNPRPLRSEWGMIGWEELDNGALVAAQPCGAPSWFPCDDTPDEKALFDVHFHTDNGYAAIITGDFISKNVSGSMTTWHYQSREPMATYLATVHVGEYDTVSLGVSESGVVVEAYVPVGDAALRGRILEDFAKQVDMLDAYEKLFGPYPFRSYRVVITEDELEIPLEAQGLSSFGANHATGEGTWERLIAHELSHQWFGNSLGLAQWNDIWLNEGFACYAEWLWFEAAGVKPAAESALEFYRGLEALPKDILLANPGAKDMFDDRVYKRGALTVHALRELLGDDAFFKAVRSYVAEGRHGLVEPRDLKRHLYAVSTDHTALDAVWQSWLRDLELPEFPSGGLD
>NZ_CP010451|351938:446240|364283_366332_+|WP_040966865.1|DBSCAN-SWA
MKRLSRAALAVVATTAVSFSALAVPAFADEASNVELNILGVTDFHGHIAQDLSKGEMGAAGLACYVESERAANPNTSFITVGDNIGGSPFVSSILKDAPTLTALSTIGVDASALGNHEFDAGYEDLAGRVSLDGTGLAQFPYLGANVEGGTPTPAASEVVELGGVRVAYVGSVTDETSTLVSPAGIPGITFTNDLSAVNAEADRIMAAGEADVVIALMHSPARATDAFSTNVDVVFAGHTHEERVETGPARDGKQPLVVIQGMEYGKFVSDVEISYDSTAKKITAIEAVNVDAATASGACGVPNALVTSVAGIVDAAKIASDVEGAKVVATIENSFFRGADSAGETGSNRGVESSLNNLIAEAGLQAINAQTPLNADIGVMNAGGVRADLEAGEVTFSEAFATQNFSNTYGVVDITGADFIEALEQQWKDPAADRPRLALGLSNNVQYSYNPNAAQGERITHVTINGKPIDETKTYRIAGSTFLLSGGDGFTAFTNGTDITDSGLVDIDLFNSYLAANTSVDVRANQASVGIELSGTALADDSSLIPGKELTVDLSALSYTGGEVTPTTVTVTLGAETVTVPVDNTIIPKLDTTGTATATLIVPAGVTELKIETDAGTTFTLPVVATSKPADGSSVGSSAGSLVAILGVLGALGGLLGVFLHSPQGAPFLTQLHALIDQSKP
>NZ_CP010451|351938:446240|392207_392981_-|WP_038582321.1|DBSCAN-SWA
MIFAANMSWEQYAAKTDGVAIIPAGSCEQHGSHLPLSTDSIIATEISRMVAEQIDGIVLPTLNYGYRSSPYSGGGPLFPGTVDLSLNTMVELASNLLDELLADGFRKILFLSAHFENQAPILEAMHLAQRQHGTDNQIVLANWWDPLKDSVMDEVFSDITFPGWDLEHAAVTETSLLMHLAPELVHSDKLPAKEAFTVPPYLRVPLQTSDIPSHGALADAVGATAGKGKIIADAAATAIAGICAYEFGVHIKTPVKL
>NZ_CP010451|351938:446240|413252_414449_+|WP_040966888.1|DBSCAN-SWA
MRKPKIMTVYGTRPEAIKVAPVIKALEQDERFESVAVSTGQHKEMLDQVNEMFSIKPAYDLGLMNKVSTLSGVVSKALEGLDEIIEAENPDVIISQGDTSTAMSAALAGFHREVKIVHLEAGLRTGNIHSPFPEEANRRIIGQVSELHLAPTEISRENLRRENFRSADTVVVGNTVIDALLEAATWETTFEDQRLNDLVESDQRIVLVTTHRRENLTAMSEIGGAVQQLAEAYPDVIFALPLHLNPKVRDIVLPKVDTLPNVIITDPLPYDQFTKLMASSTLVLTDSGGVQEEAPAFGKPVLCMRENTERPEAVLAGTVKLVGTNQARIITETRLLLDDPTAFSAMAQAINPYGDGKAAERSVAAIAALLGVGERLPDFQPEKPIEPGLDEPRLSDQL
>NZ_CP010451|351938:446240|361213_361924_-|WP_003855424.1|DBSCAN-SWA
MDASKNSDFKDTWLVVPCYNEATVIREVLENALKTFPNIVAVNDGSPDNSAEEIHAAGAHLVNHPVNLGQGAAIQTGIEYARKQPGAKYFVTFDADGQHQVKDVVRMVERLRAEDVDIIVGTRFGRPRQADDQVPLIKRLVLRTVVLLSPKTRRLGLTDAHNGLRVFNQKVAQEMNIRMNGMSHASEIVDQIDERGWRISEEPVDILYTEYSMSKGQSLLNGVNILADGFLARRLP
>NZ_CP010451|351938:446240|375042_375303_+|WP_040966866.1|DBSCAN-SWA
MTISIPTTTEDRLCFPRDEQVLLTEAMDLLTCIESSLRVADVDTQMAVARLAELYLGADDGDHFPTVLNKITQLRDRIYIQVDQAN
>NZ_CP010451|351938:446240|382936_384058_-|WP_040966870.1|DBSCAN-SWA
MSTFVDIHLVQLVPPSCINRDDTGSPKSAIFGGVERHRVSSQAWKRAVRNDFKDYLDSSELGERTLQAVKRVSQRIQELKEELSAEQAEAAAEEILKTAGIALEKKKKDETLPTKTGYLLFLSRAEIDALAELAIAQVEGNKPTKKQAREALQGPQAIDVALFGRMLADAPEANVDASCQVEHALSVHKATREFDYYTAVDDNADEDNAGAGMIGTQEFVSSALYRYATVNVDKLVENVGDADAAARAIEAFVRSFTVSMPTGKQNTFANRTRPDFVYVEVRNDQPVSLVNAFENPVRNEGKAVSLAAAKLAEYAVNGDAAYGTKPVDSFGMANTNVDSEELEKTFGDRWDATSFEDIIKRAGAAARTSTQEN
>NZ_CP010451|351938:446240|407850_408333_-|WP_040966884.1|DBSCAN-SWA
MKNIVRTVAATIIASSLLLPATALTASAQSSLSSGTFDLGMSHDSDPVAVQLEKAFEDYGLSRGHSLDLNAEMRAELLLRSVIKGHTITRNGRYLQLDPASNTLSSVSTVTPKEIQDFFEGINGGERLATSYFSGAPFRFGVAVGVKNGTYYLVTTKFTN
>NZ_CP010451|351938:446240|358197_359430_+|WP_040966861.1|DBSCAN-SWA
MGVSAFNMSDMVANKRAQRKVWLAVALSVFTVAWGGNEFTPLLVFYRGEGFFSNLFIDLLLVFYAIGVAVGLLAAGPLSDRYGRRAVMLPAPLIAILGSALIASGEETAILIAIGRVLSGISVGMVMTAGGSWIKELSSSRFEPGVKTSAGAKRASMSLTGGFALGPALAGVMAQWLPLPGQLAYVLHIILTLILFPLLITAPETRQSAHLKTKGSFWSDVLVPSALDKRFLFVVAPIGPWVFGAGFTAYAVLPSQLRDMVSAPVAYSALIALVTLGSGFGIQQFGPQIMGTSKTRGPILAMFVTVIGMIGAVIVVMNPHPWWALVVCMALGLSYGLCMFMGLAETQNIAPPIDMAGLTGIFYCLTYVGMVFPALMTWLNQWLSYPFMLGFGAVMATICLIIVSFSARRF
>NZ_CP010451|351938:446240|426881_427781_-|WP_040966896.1|DBSCAN-SWA
MFQKPQKTTADQFLGDKSAIIVDSSNLHPLHSRPKFNIYLAQIWNRRHFIFADARGRSFESPRDMLLGRLWLVLSPLLDVAMYGLLFGLLLKTSRGVENFIGFLIIGVIFFGFIQGGLTTGSGMIKESRSMIAAFSFPRASIPIARIARQFLNNSLPALVALIAALAFQWGTPPGWEMLLVLPIYVLIHIFGLGLALIVARLTAFFPDLKSLIPVAGRAWFYVSGVFFSIERFATNPTIQEIMILNPAYRFIQAVRSVVLYQTIPPYDTWLILCAWSFGLVAIGLIYFWQAEERYVNVR
>NZ_CP010451|351938:446240|357439_358111_+|WP_003855855.1|DBSCAN-SWA
MDLKLGGQVILVVGGAGTIGSEVVKLLTEEGATAVAASRSTPLSIDASDEASVRAGIDQVIAEHGRLDGLVVSSAPAAQTLSAETADDPDTVLAAIEGKAITFMKAATVALEKMREAGYGRIVALSGMNSYKTLSTAASARNAALNVVVKNLADRHAGTGITVNAISPGFVVAEPDAEVNRANGDTTVGEVAEAIAFLLSPRTASISGEIISVGHKAKGVILP
>NZ_CP010451|351938:446240|399387_400335_+|WP_040966878.1|DBSCAN-SWA
MHFCLLSLARPAKVVAPLLGAALLLSSCSSTSSDEPIQPEVASTGYSVEHAMGTTEIPETPKRVVVIDSPHLDALLALGITPVGATESGSENGFPAYLADELKDTESVGLTSEPNLEKITALDPDLIIGAKVRHEAIYDQLSDIAPTVMSEGSGTNWNEQAEITAAAVNKSDEMDKLVSDLDTRATELGEEIGADGQTASMVRFRTDNFRLYGPETFSGSVLEQVRFDLRERDWNEYSMMELSSENFGQIDGDLIFYTIPGSPEATTYPQISELWVDSPAAQQGKTYEFEDETWMVGIGVLGANEILDDLEETLS
>NZ_CP010451|351938:446240|423257_423596_-|WP_080770728.1|transposase|DBSCAN-SWA
MGAKIKSIFTKERGCYGAKRITAELNDGPSTTTPFNHKRVARVMSSLKLFGFTKKRKVITTIPAAMKPVFPDLVKRHFNALAANEVYVGDITYLPIADGSNMYLATVIDCYS
>NZ_CP010451|351938:446240|424086_424623_+|WP_040966893.1|DBSCAN-SWA
MSTKQGSGPFHLAGPSFHGRLLTVAIRHDVIEILDETSRPIVTFPRSYDHQDTTVFTPLSLLPALITKPGAWDNSPVRTLLPATVCSVLDKAHAADRSRLLAGINRASTATSFPNIIAAWEQLIEVGQNIAGPGLGMLARRIARGSDLDVPEVDLSVYDLLPTNRHTHHTDQNAPVMA
>NZ_CP010451|351938:446240|363064_364102_+|WP_040966864.1|DBSCAN-SWA
MSNKRIGVVIVSYGHEQDVANLVDTFADQLKTGDRVVVVDNRKPWVLKDTVGERLEKHGVEIINHDNGGFAAGCNVGAAHIVDDVDLLFFLNPDTVIDDPTLFNSLRRVDEQWAAFMPYLLLPDGTINSAGNALHISGLSWVTGLDEKPVEGSSEVTDISIASGACLAVRVEWWKRLGGMEELYFMYHEDTDFSARLLLAGGRIGLLHSAYVTHHYDYAKGDYKWIYIERNRHVLLLSVLPLPLLLMLIPQILGVNLGLWAIAAKENRVGLKVKSLRLLIRDLPAIFKLRRSTQELAELTPSQYLAKMEWRLDNPNLGNIGSNKIVATVYKTYYKLCMSILKLLA
>NZ_CP010451|351938:446240|435811_435934_-|WP_074508468.1|DBSCAN-SWA
MRAENARLRRELAEVKMDNEFLSKATAFFAVKQRDRKNLS
>NZ_CP010451|351938:446240|384689_386357_-|WP_040966871.1|DBSCAN-SWA
MSDNTVFNLLDEPWIEVLRIDGSPDTVSIKELLENAEHYQRLAASLETVNFAILRVLLAILYRSWDSPQWRNQMAASKHWQQKWVSRSVFDSEVEDYLDELEDRFDLRHPERPFMQVADLHTSKNEWKSLDILIPDAGEVGDLFTMRTDIASLSPASAAAFLIHTNAFDYSGIKSGAVGDDRVKGGRGYPIGIGWAGWLGGTTLEGHNLLETLLLNYVPQREQAGSDEDVPVWELEDPLTSSARPGFEDNALIAKAAGPVELLTWPQRRLRLKWENDQVTGVLISNGDALGYTVQDQVETMSPWRFSDPQTTKAKRLRYMPASVQPGRAMWRTLPNLLPNQNFAKAQTKYSDNAPQSKPAKTVEWVGQLSAQGYLDPTFPIRMRMVSMEYGAQSSSYADILSDSVHLSALLLSPDGEVLRSIARLAIERTEQVDYAVRQYNSNIAFAVSGDTASDTDEVQREFFFSIDGPFREWLTKLSESKDPDALLVEWDAQLRQTARAQAEQILSKQPPSVWSGRMKDSNRITGPVALNRLQGSLNKILGENLNSKKGVEDE
>NZ_CP010451|351938:446240|443180_444590_+|WP_040966904.1|DBSCAN-SWA
MTEHYDVVVLGAGPGGYVSAIRAAQLGKKVAVIEKQYWGGVCLNVGCIPSKSLIKNAEVAHTFTHERKTFGINGEVTFNYEDAHKRSRGVSDKIVGGVHYLMKKNKITEIHGLGNFKDAKTIEVTEGKDAGKTITFDDCIIATGSVVNTLRGVEFSENVVSYEEQILNPVAPKKMVIVGAGAIGMEFAYVLGNYGVDVTVIEFMDRVLPNEDAEVSKVIAKAYKKMGVKLLPGHATTAVRDNGDSVEVDYQKKGSDKTETLTVDRVMVSVGFRPRVEGFGLENTGVKLTERGAIDIDDYMRTNVPGIYAIGDVTAKLQLAHVAEAQGIVAAETIAGAETQTLGDYMMMPRATFCNPQVASFGYTEEQAKQKWPDREIKVASFPFSANGKAVGLAETDGFAKIVADAEFGELLGGHLVGANASELINELVLAQNWDLTTEEISRSVHIHPTLSEAVKEAAHGISGHMINF
>NZ_CP010451|351938:446240|353578_355615_+|WP_040966860.1|DBSCAN-SWA
MSQEQPQIGSRLSRVIEQDGLQFRDLDGDGVLVPYEDWRLTPAERAADLVKRMNVEEKAGLMIIGSHYPGYSPLAPESEGKDAEKCEPLLNPVDMWREDNPITGVPFTEPVLATSSTENAINLRNQRYLIVRDNLPARELATWTNAVQEVAERSRLGIPVVFASNPRNHVALVAQFGVNESAGVFSEWLGELGLAALRDTELMETFGTEAAKEWRAGGVHKLYGYMADLASEPHWSRFNGTFGEDPELISDYIAAVVRGLQGPELSKKSVATTIKHFPGGGVRLDGHDPHFHWGQTNEYPTEGALGKYHLPPFQAAIDAGCASIMPYYARPMNNSANQLDQQLWQNPTTQFEEVAFAYNRTFIQDLLRDAMGHRGYVNSDSGVIDAMMWGVEELSEPERFAAAVRAGTDIFSDMANPRRLLEAVAEGHLDESELNQPVQRLLEEIFQLGLFENPYVSEDEAEKIIGAPEVSALGNKAQLDSVTLLRNNPSVLPLDPAASLKIYPLVTGRTKIDEVQLQLEAAIRAELPGVTLVSSESEADLAIVWARPEIALFEDDLEGVSLSVDPRANGVDVERVQAVEAAVPTILAVNFTNPWVLSEIEPGAAAVVGTFEIKPEFLLKALTGQEGGPKGKLPLTVPASMQAIADSPRDIPGKFLDESYTYVDSAGMAYKYGHGLNF
>NZ_CP010451|351938:446240|415918_417436_+|WP_052461391.1|DBSCAN-SWA
MKRVFSLATIVASYLWLDSRSFMQKLGERARLSNLKIPKFLFLAELTGTSPAYKFVELGELSKAQELLVEKGKLSISERRLNNRVTQTLSELRLGPVKNTVRVARYGEKVKVLYFLTNSLPYTTSGYTKRSHSILEAVIDNDVEIQAVTRMGYPLTIGKWPNGNAQFVDGVKYHRVFPWIFSRRTEKFYEKSVELLSDLAKDLGVTVIHTTTNFPNAIVANRVASKLGLPWIYEVRGELESTWLSKLPKDKQNKAEESEYYRLARQQETSYAKAADAVVVLSDISRKQLVERGVDPEKIFVIPNSVEQSLFEKEYDKSELRRKHGISEGSIVVGTVSSVVQYEGLDTLLKALMKLPQQYRGLIVGDGVDKPRLESLAESLGVLSRVDFVGNQNPQTIDEWYKLLDIFVMPRKDTPVCRTVTPIKALTAQALGIPVIASDLPALREVTGGIESYVIPEDARDLADKILAARPHTQGVEWAASRTWNVAAKNLNSIYQRVFSSSQAT
>NZ_CP010451|351938:446240|431991_432168_-|WP_080770729.1|DBSCAN-SWA
MKREVLQDSKTFANQLLCRRNVFRWCTRYNTVRRHSWCKYLAPVVFEERGSVLLKSTS
>NZ_CP010451|351938:446240|419819_421454_+|WP_052461392.1|transposase|DBSCAN-SWA
MTNYQLIMTLLLRGNSYRTIQAHCGAAHATIAKARKALDQHNLTTEAQIMGHSNEDLALMIGDGRATTAGEFVTIDIDTIIKARTGRKKTPLNVLWANYLNIPAPEGLRHYSYERFRQLVNRHIAAQGLTTRVHHIPGHTCQVDWAGTTMQLIDPISRKTTKVSIFVATLPYSGLVFAHGFLDQRQPSWLAAHRLAFDYFGGVPEVIVPDNASTASNVITTGDRARRVNTSYEEFLTHYNTAALPARPLRPKDKGNVESGVKVITNWAILKLAGRDFTNLDDLNGALRGAVDEINDRTPFRDQPLSRRQIFIDAEQDLLAELPHQPFVSTVWKKAKVAPNWHITVSTVHYSIPYTYVGDTVDVRIRGEQLDVFAGGITIATHQVTTQRGAYVSDIAHCPPGMEDPTQLWSAAYFLNQAARVGPFTRKVIDALLAAKPIVAQGYLPARNILGMGKGENKIILEEACRRLVGEGDQPRAVSYTAVKNMMAAVRSDLAARPTTTTEVPPRPSGQDQRSQHHRRRGGLLGGADQFSLDSLMGKKEDQP
>NZ_CP010451|351938:446240|380251_380605_-|WP_074508531.1|DBSCAN-SWA
MITVILSSPPEKLRGHLTRWLIEVSPGVFVGRPTARVRDEIWDMIVSTLTNGRAVMTFPTRDNEQGFDIRVHRSQWEKTDFEGVTLMRHPISTAKGSMKAGWSTASQHRAARRRKAK
>NZ_CP010451|351938:446240|360839_361217_-|WP_040966862.1|DBSCAN-SWA
MTQTTTQIIIQILLLLATAALALYFLRNRRKARAKAWVKIGFVVFIFAAVWAVIRPDDLTQLANFVGVDRGTDLMLYALVVAFMFTTLSSYVRFREQELRYSKLARAVALQNAVLPEDSQGSDPA
>NZ_CP010451|351938:446240|406024_406510_-|WP_040966882.1|DBSCAN-SWA
MRSSLTKALAVLISGVLISPMSAGMAHAELSFGSSSFGSSGLSETRDKKAVEFKNALEEFFIATGRTKTDNAEAIANDYYQRAVNGELVFFEDMFFTDYIESERLYVVANSIPPERIEDEIAIIKQNTSFLNPDGEKDTGAIGVRVDFENGRYHSVQVYVG
>NZ_CP010451|351938:446240|389649_390681_+|WP_040966872.1|DBSCAN-SWA
MMREPAELKPFKEHDELLQMLEENGLKIPSSEIAKKELRRHGYHRLSGYRYLFREMLPFEQQNSETRTFRSKQHLAGSSFEDVIALAEFDSRLRLSIVEALADFEVRLRTAVAHTLAAKDELAHLKVDKLDRRSCLNTAKGKRETNHEVFCKEVARVTAMAIRSDDFAKHHDETYGSDLPVWAVVEHLTFGSLHYLFGFMKNEDKRTVANAFGLRHPKALEKWLYALVDLRNLSNHSARLFNRSLKRSIVIPPHTVSPGGLLKQTEEFLDRNKQEKDRLYAVVAVLAYLLKSHEFGSEWPTKFREVMLTFPYIELAEFEDPLVSPQKNMGFPEHWQGDELWLP
>NZ_CP010451|351938:446240|386377_389152_-|WP_080770707.1|DBSCAN-SWA
MQIVIDLEVFWAKFVEKTSEHMSLLQHSRDITSVINEVSKKLLAPASEEFLQSILGETPLHEILTLAAISHDVGKASPYFQQKVPSLSQRVTHQGYGSDVTSKEIYANPHSIISAHTLIAWFEQHRGFKLSPPDREFWFHVIAGHHGSYSEFSLPSDALLREIRIWPEWQEARFALLDKLTSEHDLDEESLHGLASIFGDRMENNMLSTSAAALITGLLISADWVASSSDNFPLTNGEPQDQDYRTEDALTRINLGNHWQPGEVTTESFLDRFSLPASATMRNVQEAVVELGHQLDKPALVILENETGSGKTEAALALAEIMAEKFGFTGLFFAQPTRVTSDAIFTRVAEWLIHSVPEDTISTVLAHGKAEFNDDFKAITTGDLTAIYDDDSSNGDSPLEATQWFRGRKTGLLASVAVGTIDQVLFAVLQSKHNVLRHLGLASKVVIIDEIHAADAYMRVYTTRLLEWLGLYGVPVIALSATLPPKTRKQLIDAYQQGASRYSGRKARIDKAPVYPRITWVDGEKSGTITPEHDGLTRTTHYSFLEGDLEEMADEALKLSVDGGCIGIICSTVSRAQELYKLVSSREEEVVLLHSRFLTSDRAILESALVKKLGRKAGASRPKKLIVVSTQIIEQGLDLDFDAMITDIAPTDLIIQRIGRVHRHQMLNDSRPDSLKVPQLKIFGTGLPDIEASAPEIQTGSKRVYRHAPLLRSIRVLADHATNTDGTITTPDDVESLVTSSYDTKKTAPEAWKDAWTAAHVEERKFETDQESRAETARIPDPLAGKLAEWTKSPSLADEQAAVAQVRDADESFEVVVVQNRMGRLFALPHIKDLEGQSVDGVMELEYRTARTLATCTVRLPEWSLTDDDLFDLEADGQESWQKSRWLKGSLPLVLDENLERALEQYILRYDEQLGLLLERKEQQ
>NZ_CP010451|351938:446240|397005_398025_-|WP_040966876.1|DBSCAN-SWA
MTSLLVTGGAGFIGANFVRQTVEQHPEYTHITVLDKLTYAGNADNLKGLPDSKVALIEGDICDAELVDTLVKDHDITVHFAAESHNDNSLNDPSPFVHTNLIGTFVLLEAVRKHNKRFHHISTDEVFGDLELDDPNRFTETTAYKPSSPYSATKAGSDHLVHAWIRSFGIQATMSNCSNNYGPYQHIEKFIPRQITNILAGLTPKLYGTGEQVRDWIHVDDHNDAVHLILSKGKIGETYIIGADNDHVNNKQVIELICELMGLDKNAYEHVADRPGHDMRYAMDSTKLRTELGWAPKYTDVDSGMRKGLEQTIDWYRDNEAWWRGTKDNVEATYAKQGQ
>NZ_CP010451|351938:446240|438754_440665_-|WP_052461396.1|DBSCAN-SWA
MDKGKVWGEWLGATDAIDQNTSFEKSLELLGIAHEEITKMQEKLTQYQKAAVSYVEKSATANQTTKRVTKVERLKKLSKRLANGDVSKREGFRKLLWILVKAPAEVGLVSKNSGAAALLGKPYISNFAGSNVIRNALGKGNYEEAYLWGRALFPKHRQNKDFIALLEQSAVKRGNISQSVALANHKLKNAWIKPNALSIVQGRLNDLEAFPTLGNHPVKPEERKSGVIVHMAKESVPYRSNGFCARSFENLKAEKLVDYTPIVLTEPGFPEETEWEGEYSETIESIQHIRLMPGCEDLTRKLPLDEFTQLYADLALKEVLSIKPQAIHVSSGRRGYETAKAGLAIGKATGIPVVYEIRSFFEGTWTAEIERESESETYQKRLSAERACAIRADFVLTISETMREEIQTWGINPEKILVVPNGVHAQKFIPAPKNENLEKNLGLTKEFIVGYVSNLDHSRESQETLVEATAILRKKGLNVTCLLVGGGPRLSKIREVAENLGIGDYVITTGSVPHDDIADYYRLIDIFVVPRRDERAARLVTPLKPFEAMAAGIPVITSDLPALIEIVDPPQRGLTFKESNPLDLATKLDYLIKHPKLRKSLSENARKWVSTERQWSGNSEIYRQTYETVKELKNEK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_040966803.1|351938_353120_+|transposase	IS3 family transposase	NA	NA	NA	NA
WP_040966860.1|353578_355615_+	glycoside hydrolase family 3 protein	NA	NA	NA	NA
WP_003863269.1|355667_356774_+	S-(hydroxymethyl)mycothiol dehydrogenase	NA	NA	NA	NA
WP_003863266.1|356774_357410_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_003855855.1|357439_358111_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_040966861.1|358197_359430_+	MFS transporter	NA	NA	NA	NA
WP_038582304.1|359451_360387_+	NAD-dependent epimerase/dehydratase family protein	A0A2K9L4U8	Tupanvirus	3.2e-43	34.3
WP_040966862.1|360839_361217_-	DUF2304 domain-containing protein	NA	NA	NA	NA
WP_003855424.1|361213_361924_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_040966863.1|362003_363026_+	hypothetical protein	NA	NA	NA	NA
WP_040966864.1|363064_364102_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_040966865.1|364283_366332_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_040966866.1|375042_375303_+	hypothetical protein	NA	NA	NA	NA
WP_074508531.1|380251_380605_-	type I-E CRISPR-associated endoribonuclease Cas2	NA	NA	NA	NA
WP_040966867.1|380601_381582_-	type I-E CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_040966868.1|381587_382238_-	type I-E CRISPR-associated protein Cas6/Cse3/CasE	NA	NA	NA	NA
WP_040966869.1|382238_382937_-	type I-E CRISPR-associated protein Cas5/CasD	NA	NA	NA	NA
WP_040966870.1|382936_384058_-	type I-E CRISPR-associated protein Cas7/Cse4/CasC	NA	NA	NA	NA
WP_052461388.1|384076_384697_-	type I-E CRISPR-associated protein Cse2/CasB	NA	NA	NA	NA
WP_040966871.1|384689_386357_-	type I-E CRISPR-associated protein Cse1/CasA	NA	NA	NA	NA
WP_080770707.1|386377_389152_-	CRISPR-associated helicase/endonuclease Cas3	NA	NA	NA	NA
WP_040966872.1|389649_390681_+	Abi family protein	NA	NA	NA	NA
WP_040966873.1|390754_391816_-	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L7I1	Tupanvirus	6.9e-66	38.2
WP_038582321.1|392207_392981_-	creatininase	NA	NA	NA	NA
WP_003863255.1|392994_394308_-	MFS transporter	Q6JIH2	Burkholderia_virus	1.8e-60	35.5
394012:394026	attL	NA	NA	NA	NA
WP_040966874.1|394789_395653_-	glucose-1-phosphate thymidylyltransferase RfbA	H9NC64	Sphingomonas_phage	7.2e-98	60.6
WP_074508533.1|395653_397009_-	sugar nucleotide-binding protein	A0A1D8EQE2	Escherichia_phage	1.3e-24	34.6
WP_040966876.1|397005_398025_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.6e-78	49.2
WP_040966877.1|398062_398644_-	dehydrogenase	NA	NA	NA	NA
WP_040966878.1|399387_400335_+	iron-siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_038582347.1|400440_401082_-	hypothetical protein	NA	NA	NA	NA
WP_040966879.1|401291_402551_-	hypothetical protein	NA	NA	NA	NA
WP_040966880.1|402550_403933_-	M1 family metallopeptidase	NA	NA	NA	NA
WP_040966881.1|403938_405954_-	S9 family peptidase	A0A1V0SHT0	Klosneuvirus	1.8e-27	33.2
WP_040966882.1|406024_406510_-	hypothetical protein	NA	NA	NA	NA
WP_040968130.1|406653_406959_+	hypothetical protein	NA	NA	NA	NA
WP_040966883.1|407136_407637_-	hypothetical protein	NA	NA	NA	NA
WP_040966884.1|407850_408333_-	hypothetical protein	NA	NA	NA	NA
WP_040966885.1|409103_409580_-	hypothetical protein	NA	NA	NA	NA
WP_040966886.1|410141_411353_+	hypothetical protein	NA	NA	NA	NA
WP_040966887.1|411599_412691_-	esterase family protein	NA	NA	NA	NA
WP_040966888.1|413252_414449_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	5.6e-24	27.8
WP_040966889.1|414626_415922_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_052461391.1|415918_417436_+	glycosyltransferase	NA	NA	NA	NA
WP_040966890.1|418005_418224_-	hypothetical protein	NA	NA	NA	NA
WP_040966891.1|418298_418592_+|transposase	IS3 family transposase	A0A1P8CWP5	Bacillus_phage	7.1e-05	33.0
WP_077313832.1|418720_419485_+|transposase	IS3 family transposase	U5P429	Shigella_phage	1.3e-26	35.6
WP_052461392.1|419819_421454_+|transposase	IS21 family transposase	NA	NA	NA	NA
WP_052461393.1|422280_422481_-	hypothetical protein	NA	NA	NA	NA
WP_052461394.1|422572_422824_+	hypothetical protein	NA	NA	NA	NA
WP_080770708.1|422876_423224_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_080770728.1|423257_423596_-|transposase	IS3 family transposase	NA	NA	NA	NA
WP_080770709.1|423771_423966_-|transposase	transposase	NA	NA	NA	NA
WP_040966893.1|424086_424623_+	hypothetical protein	NA	NA	NA	NA
WP_040966894.1|425395_425656_+	hypothetical protein	NA	NA	NA	NA
WP_040966895.1|425804_426077_-	hypothetical protein	NA	NA	NA	NA
WP_052461395.1|426079_426892_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.5e-07	22.8
426773:426787	attR	NA	NA	NA	NA
WP_040966896.1|426881_427781_-	ABC transporter permease	NA	NA	NA	NA
WP_040966897.1|427966_429694_+	hypothetical protein	NA	NA	NA	NA
WP_040966898.1|429696_431577_+	glycosyltransferase	A0A1V0SAE6	Catovirus	3.2e-26	27.8
WP_080770729.1|431991_432168_-	hypothetical protein	NA	NA	NA	NA
WP_040966899.1|432550_433756_-|transposase	IS110 family transposase	NA	NA	NA	NA
WP_080770710.1|433995_434355_-|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.2e-06	33.3
WP_080770711.1|434915_435776_-|transposase	IS3 family transposase	U5P429	Shigella_phage	2.5e-34	35.8
WP_074508468.1|435811_435934_-	tranposase	NA	NA	NA	NA
WP_040966891.1|436005_436299_+|transposase	IS3 family transposase	A0A1P8CWP5	Bacillus_phage	7.1e-05	33.0
WP_077313832.1|436427_437192_+|transposase	IS3 family transposase	U5P429	Shigella_phage	1.3e-26	35.6
WP_080770712.1|437098_437425_-|transposase	transposase	NA	NA	NA	NA
WP_080770713.1|437610_438765_-	glycosyltransferase	NA	NA	NA	NA
WP_052461396.1|438754_440665_-	glycosyltransferase	NA	NA	NA	NA
WP_040966903.1|441238_442492_-	UDP-N-acetyl-D-mannosamine dehydrogenase	M1HNJ7	Paramecium_bursaria_Chlorella_virus	1.4e-20	24.9
WP_040966904.1|443180_444590_+	dihydrolipoyl dehydrogenase	NA	NA	NA	NA
WP_040966905.1|444746_445670_+	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	1.5e-45	40.3
WP_074508513.1|445718_446240_+|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP010451|3004795:3063156|DBSCAN-SWA
CTCAAGCACTTAACAGCGACGCTACACCACCAACCCTCTCCTGTACAGACCCATCATCACGCGCACCATTAAGACGCACCACACCAGCAACTTCCTGAACCACCGGCTGTCCCACATACCGCTGCGGGAACTGCCGGTAATGGGCATCCAACGCCTGCACACGCAACCGATGCACCGCCCTCCAACTACCATCAAACACCGACTGTGGAGTATGCCCAGCCACACCAGAATGCGGATGAACCGTGTTGTAATACACCACAAACTCCTCCACCCACACCCGGGCCTGATCCATCGATGCAAACACCTTCGGATAAAACGGCCGATACTTCAACGTATGAAACACCGACTCCACAAACGCATTATCATCACTCACCCGCGGCCGAATCAACGACAACGCCACACCATGATCCGCTAACAACCGCCGCACCCTCGTCGATGTCATCGCCGACCCATTATCCGAATGCACCGTCACCACACCCGGATTATCCGCTAACACCTGCGTTAACAACTCCACCGCGGTGGAGGTATTTTCCGTCGGCGCGACCTTCGCCCCAACAATCTTGCGGGAAAACAAATCAATCGCCAGATGCAACGCATAGGTCTTACCACGTACCAGCGACGGCAAGAACGTCACATCCCAACACACCACCTGACCAGGCTGTGTTGCTTCCAACCTCGGCTTAACCCGTGGCGTTGGTGATCGTTTCACCGGGGACAGGGCACTGACTCGGTCTTTGTGTAACAACTTGTGCTGCTTGGCAACACGCCACCATGTACGTAGTGATGCGCGGTAGATGCCTTTGTTAAACAACATGTTAAACACCCCACTAACGCTCAGTTGTGGGTACGCGGTGATCGCATCAACAATGAACTGGCGTTCGTGTTCTGCCAACGCTTGACGCACCGACGACACTGCTGGCTCCTTCCCCTGCCAAGGCTCTGGTGTGGGTTCCACACCAGGTGCTGCTAGTTCCACACCAGGTGCTGTTGGTGCTGGCACGGCCTGCAGGACAGGTTTCGGTGCAGGACAGGGACGCGGCTTGTTGCGGTAATACGCCGTTGATTTCGACAGCTTGATCAGCCGTAATGCCTTGTTATGGCTCAGCCTGGCACAGGTGGTGAGATCTGTGATCAAGGTGTTTTCTTCCTTGAGTCCTTGATCAAAGGCGCGTTGCTCATCCACGTTTAGGTGGCGTCCTCCTCGTCTAAGCCCTCGCCAGGATTGGGCCTGGTCCCAATAGCTTTTCCCAAGATATCGATCACCATTTGATTCTGATGGTCTTTTTGCTTGTAGTGCGCGAGTTCTTTCTTCAGCGCTGCGATTTCTTTGAGGTACTCGTTTTCCATGATCGTGGCTCTTTCTAGTTGTTGGGCAATCATGTGGCGTAGTCGAACGATTTCGACCACGGTTCGGGTGGTCATCAACCCGATCTTGCGGGGTGAGATATCAGCGTCTAAGTCCCCGTCGGTCATAGCGGCGCACCAGGCCATGATGGTGTGCTTACGGAGTTGATAAAACGTGAGGAATTGCTGGCCCTGACCGTGTGGTTGAGCTAAGTATCCTATGACCAGGTCACGTTTGTCATCAGCCGTTAGTGTGGTGACATCGTCGACTGGGGTGGTGCGTTCGATCCCGAAGCGGTGGGCATCATCAAAAGCATGGGGAAGCCGGCTGAAGGTGCTTATTGCTGCTAGCCAGGTTCGAACGGTGCAGTGGCCGATGTTGTTGGCTGTGAGGAAGGGCTGGCGGTAGCCGTGCGGCAGGGCGGTGTAGATCCGCATGAACTCGAGTCGTGTTTGTGGCTCGTAGTAGCGTCGCCCGTTGGCGGAGATTCGATCTGGTGGGAAGATCGGCCACTCGATGCTGTGTGGGTCCGGCGCCGGTGGTAGCTGGGGTGCTGTGGGGGCAGGGGCCGGGGGCTGTGGGATCTGGGGTAAGGCTTCGGGACTGATCAGATCCAGGTAGTCCTGAAGGACTGAGAAGGGGATGGACATGATGAACTCCTTGCTAAGGATGGTGGTTCACCACTGACCTGACACTGAGAGTTTTCGCGCGTCGAAGTGTGCATTTGAGACCAAGGACGGCTCTGGAGAATCCTTCCTTGGTTTAAATACTCCCCAGGACAGGTGCTGTGCGCGCACCTTGTCGAAGCCAATGGCGAACCGCTGCGGTGGCCCTGCAATCGTCACCGTTATAGCTGAGCAATTGGGCGCGAGCGGCCTTAGCTTCTGGTTCGGCAGCCGTGGAAGCAATGAGATATGCGTGGAGGCTATCTTCACCTGCGAAGTCTTCTTCCTCCCAATGGAATCCAGCTGCCGGCGCGAGTTGTTTCAGACCTAAACCACCGGGGCCAACAAGTTGGGAGCGCGCGACAGCAAACATGTCATTCCACTGGTCAGAGCTAATGAAGCTGCGGATTTCTTGCTCGTCGGGCACACCTTTGACTTTGCCGAAGAATCTGCGAGCAGTGGAGAGCATCCAGTGGTTTTCGCCGTTGCTGGCATAGCAGAACACACCGAAGGTTTGTCCCTGCTGGCGAGCTTTGTCCCGGCGCGATTTCAGCCAGGACCAGAAGCGAGCAAAGTTCTCACCTTCGGCAGCCTCACCGAGATCGGACCAAATGACAAAAGGTATGTACGTTTTGCCGTCCCAAGCTCCCCACAAATAGGCACCTAAATCTAGGTAGGCTTCCACATCGACGTCGATTTCCACATCGAAACGTGGGGCGCTGGTGTGCGCCTCGCGTCGAAGGACGGGGATTTCGGCGCGCCAGGCGGCAGCGACGTGGGAGATTTCGCCGAGGTTGGCGTCGATAAGCGCTGTTGTGGTGTTGATGCCTTTTTCGCGGTAGGTGTCTGCGCGGTCGCCGGTGAGGAAGAGGCTGATGTCATCGGCGGCTTTGAGTTCTGGTTCGCATTTGGGCCAGAATCTGCAGGTTGCGCACTCTTTTACCCGTCGAGGTGCTGTCGGCGCCGGGGTCAGCAACGCGCGGTGAGCTGCAGGGATGTAGCGGGTGACATCCACTAGGTATGCCCAATCGCGGTCCTGTCCCACGACGGCGCCGATCGAAGACTCGGGTGCTGCTCCAGCTTCCTCCAAACCCATCAACGCGAGAGTGAGGCGATAGCCATCGATCGTGTGGTGGCGCAGCGTTGCCTTGACCTCTAACGGCTGCCCCAAACCAAGGCGAGTCACGGCAATGCCCTGCATAGTTTTGTGCGGATCCGGACGGGCGACACGGTGATTGCTCACCATCACCGGCATGTACGTGCCATCCGGATTGCGCACCAAAACATCCACTTGGACTTCCCACGCCACCCCTTCGAGGGTGCCCGTAAACACTGCGCCGGTAATCAAAGTGTCGCCGGCAGCAATTGCCTCGAGGGTATCAAATTCCGCCAATTCTGCGTCGTTATCTAAATCCGCCCTGGTGAAAGGAATTCGGCCACGCTTTTTAGGCTGTTCTGGAAGACGATCCAAAACCTCCGCCAAACCCACTTCACGGCGAGCCCTGCGCTGCATCGTTGCAGGTAAAGGAGAGATTTCTGGGAAATTTATGCGCTGGACCTGACGGTACCTACATCCCACCAGATCACTTGGCGTTAACCGTTCCGATTGCATTCTTCCCACAATGACATGAGCTTATTGCAACATCGTGGGTAAAGTTGAATCGAGAAGTCGAGAAATAACCGACCGATGAAAGAGTTGAGACGATAATGGGCATCTTCGAAGCCATCCGAGCCGCACGCGCGAAGACCAAAGCTGAGATCAAAGCAGCCGAGGCAAAAGTAAAAACTGAGGCGAAAAACAAAGCAAAGCTAGATCTCAAGCGCGAGAAGCTTCTTGTCCAGCAGGAAAAGAATCTGCTCAAGGTTGAAGAAAAGGGCCTGAAGAAGCGCAACAAGCATGAGCTGAAGATGGCTAAAAATATCCTTGAGCAAAAACGCCAAGGACGCCTGAACAAAGACAAGGTGAAGCGTTGGGCTGGCACCGCACGTGTGCTCACTCCACTGCTGCTGCCTATTATTTATCGACTCTCCACCGAAGCACGCGATCAGGTTGTTAAGGGACGTGCCCGTCGCGCAGGTGTCACCGCGGAGCAGCTTAGCCAATTCGCAGGTCACGCAGCAGCGCTGAAGGCTCGTATTCAGGGCGTTCGCGAAACCGCAAAGAACTCCGGTCTCCCTGCTGGCTTTGTACGCGATGTTGAAGAGCGTCTCAATGAGCTCGAGGCTGCTGCGAACAACTCTGAGTTCATGTCTCCACAGCAGAGGAACCGTGCGCACCAGTCGATCAGTCGTGATCTGAACCAGGTGTCAGATCAGATTCAGGATCGACTACTGGACAAGTAGCTGCTGGTCGAGTCGCTGCCGGGATTATTTTGCTTCCACCACAGTGGTTGTGGTGGTGATGAAATAGGAGATGACCGCAGCCACAAGCGCGGCGCAGCATCCGATGATCAGAGTGGTCATGAATCCCCCTAAGGTGGGTACTCCGCCACTCATCATTCCGGCCAACACTGCACCGATGACAGCTGATGAGCCGGTGGTGGCCAGTGAACGCATAAGAGAGTTGAAACCATTCGCTGCGGCTTTCTCCGTGGCTGGTACGGCACCCATGATCAAGGCAGGCATGGAACCAAATGCCAGGCCAATGCCGATACCGACCACGAGACTACACACTGAGAACAGCACCAGGGTGGTCAAAATAAGTGCGTTGTCTGCATCTCCTCCCGGTGTGCGGTTGCCGATAGTGAACAACACTGTGGCAGTAAGCGCATAACCGACTGCGATCACAACACCCGCAATTGTCAGCGTCACACGAGGACCATGAGCAGCGCTAATGGCTGCACCTGCATTCGAAATCAACATCATGCCTAGACCCATCGGGATCAGCCAGATGCCCATCTGAAGCATGCTCTGGCCTAGACCGTAGCCCAGAATTACGGGCAGCTGCATGACCTGAGGCAGGATCAGATTCATTCCATACATGGTGAAACCGATGAGGATGGACGCAATATTTGTCATCAACACGGTCTCCCGAATAGTGGTGCGCAGATCAATCAAAGGGGATTTCTGGCGGGTTTCGAACCAGCCCCAACCCACCAAAATCACCAGCGCTGCCACGAATAACCCAATGGTCAGGGCACTTCTCCAGCCCCATTCTGATCCCTTGGACACCGCGAGCAACAATGCGATAAGTCCCATTGCAAGGCCGAGAGCACCGAAATAATCAAAGCCGCCACTCCTCACGATCCTGGGGCTAGCAGGAATCGCCTTCCAAATGACCGCGCCAACTGTAAGCGCTACCAGAGCGGTGAACCAGAACAGCACCCGCCAGGACGCAAACTGGGCAATAGCAGCAGCCAGCGGTAGACCGAGTGCACCGCCAATGCCCATGGAAGAACTCATCAAAGCAATGGCAGACCCTGCTTTCTCCCGGGGCAACAAATCATGCATGAGAGAAATGCCAAGAGGAATCAGGCCAGAGCCAAGCCCCTGGAAACCACGGCCGATGATCATCGGAATCAAATCCGCCGACACAGCGCAGATCACTGATCCAAGAATGAACGGGACAAGCGAGATGAGCATCATCTTTTTCTTGCCGTACATATCTGCAAGCCTGCCCATCACAGGAGTCGCCACTGCGCCCACCAGCAGCGTCACAGTAATGATCCAAGAGGCATTAGCAGCCGTGGTGTTGAAGATCTCGGGCAACCGACCAATGATCGGAATAACCAGGGTCTGCGCTAGGGAAACAGTGATACCAGCTGAGGCGAGAGTGCCCACCAGCAGGCAGTATTTGATCTGTGGTGTGGCTGATTCGGGAGAACTCGATGACATTATGTGTATGGTACATATTTTGTGCATGATGCAATAGCTGGCAAACTGGAGAGCCATGAGCACCGACCCCATCGCGGCCCTAGAATACGAATCCATCATCTTCGCCCGACACCGGAATCAATACACCGGCCAAGCAGGTACGAATGCTGGCGTCCTCGATTCCAGCGGCTACAACCTACTCACGCTGCTCCAGTTACGTGGCCCCTCCACCATCGGCGAACTCAGCGCCATCACCGGCCTAGACGCATCTACCCTTAACCGTCAGACAAAAGCCCTACTAACCAAAGGATTTGTCGAACGCATCCCAGATCCCGACGGTGGAATCGCTCGGAAATTCCACCCCACCGACCTCGGCAATGAACTGCTCAACGAGGAACGTACATCCAGCCAAGAAAAATATGCCGAGTTACTTTCAGACTGGCCCGAAGAGGATCTACGCACCTTCGTCAAACTTCTTGAAAAACTAAATAAAGCCGTGGAGACACGCGTCGGAAAGCATTGGCCGCGCCCCTGACTCAGCCCAAGCCAGAGCCCGTGCCCCTGCTCAAGCCTCGGGATGCTCCCGTAGGCCAACCCCGGCGCGGATACCTAAAGCCTTGCAGCAACCCCCTCTACAGCAGCCCCTGCTCACGTGCGGCTGCGACAGCGGAGGTACGTGACCGCACGCCGAGCTTGTCGTAGATGTGCACGAGGTGGGATTTCACCGTGGCTTCTGAGAGGAAGAGGATACGGCCAATGTCGCGGTTGGAGGAACCGCCGGCGACCAGTTTGAGAACCTCCAGCTCGCGTGGGGTGAGTGAGGTTTTGGGGGTTCGCACGCGAGTCATCAGGCGGTTAGCAACCATGGGTGACAGTGTGGAGTCACCTTCTGCTGCGGATCGTACTGCTGCCAGGAGTTCGCTCGGTGGGGCGTCTTTGAGCAGGTAGCCCAGTGCGCCGGCTTCGATTGCGCCGAGGATGTCTGTGTCGGTGTCGTAGTTGGTCACAACCAGGACTTTTGGCGGGTTATCGATGTTTCGCTTGATGGCTGCGGTGGCGTCTGCGCCGGTGGATACCTGGGTTCCTTGGACGCCGGGGCCGAATCGGAGGTCCATCAAGATGACGTCGATTCCGCCTTCTTGGGCTGCCTGCACGGCACCTTCAGCGGTGGAGACTTCGCCCACCACTTCAATGTCCTCGGCGCTTTCCAGCACAGCTCGGAGTCCGAGCCTCACGATTTCGTGGTCATCAGCAAGCAGCACGCGAATCATTGTTTGAACTAGGTCCTTCCCAATGGCGCACTTCGTTTCGAATGAAAATGCGCCTTCAAGAGTATCGATGAGCAGATGAATCGTACTTTAGTCTAGCCTTACTCATCGTCAGTTGGAGAACTTAGTTCAACCTCGCCTGTAGCACTTGAGTCCGAATCTGCCAAAACCGGCGCCCCGACAAACCCCTCTGGTGGCTCCACCGGCAATGCTGCAGATACCGCAGTACCCTGCCCATATGCAGATTCCACTATAACTTCGCCGTGTAATTCCATCGCACGCTGCTGCAATGCGGTTAAGCCGATATGGCCAAGGCCAGCGGGGGTACTGGACACTTCCGAAGGCTCAAAACCCACACCGTCATCAACCACATCAAGGCGTACTTCTGTGTCTTCGTAGGTTAGTGTCACGTGGCAGTTTTTCGCCTCTGAGTGTTTCGCCACATTTCCGATCGCACCTTGAGCAATTCGCAGAAGGGTGGCTTCAGTTTTCATGGGCAGTTGGCGAACATCACCGTCGACAGAAATCACAAAATTAATACCCAACAACGGTTCTGTGACGCGGTGAAGTGCTGCTTCCAAGGAGGTTTTAGACAGCGCTGCTGGTTGCAACGCCGCAATCATCGCGCGAGCCTCACTGAGATTGTCGGAGGCTGTTTGTCGGGCAAGGCGCATCTTCTTCACGATCGCCTCCTTTGGCTTCTCTTCCATCTCAGCAACGAGAATCTCCTGTTCAGAGACATGCAGCAGCATTTGAATGGAGGAGAGTCCCTGGGCGACCGTGTCGTGAATTTCATGCGCAATACGTTGACGTTCCGCAGCGATACCCGCATTTCGTTCCGTCACCGCCAGCTGGGAGCGAGTTTCAATCAACTGATCAATCAATTCCTGCTTTTCATTATTCACCCGCCACAACGTGCGGAACGCGTAATCAATAGCCACGGTCACGATCGCAGAGACCACCGGACCCATCACACCACCAAAGGTCAACCCCACGGAATACTGGCTGGCAATCGCAATCGCTGTCGCACCCAAAATCGCAATAATGCCTCTCACGTCAGGCATCACCTGTAGATAGAGGAAAAACAGCGGGAACAGCAGATAAATGGACACGGGCACGATCGGCACCATAAAAATCCACACCAGCGTCAGCACAAACAGCCAGCCCAGCTGCATGCCGTGGCTCAAATCTACGCGTTTGGTTGATCCATAGAAGTACAGAAAACCCCACACAAACAACAGCACGCACGACAGCGCAAACATCGGCAGCGTCAGGCGGGCGGAAGCTCCCAACCCCACGACCAGCAGCGAGGCTGTCAAAATGTGGATACTGTTGCGATAGCTCATCGCGCCCGGTTGATTCCCCTTCTTCACAAGGGTTTCAACATCGAGCTCATTGCGTCCGGTTTCCGACACACGATCTAGGCTTGACTGCATGCGTCGTACATTACCTACTATCCTCGCTGCTTCCATCATGCTCACCGCTTGTACCCCGGCGGAACCTGAAGCAACCCCAGAGACCACCACCGAAGCAACCCCGGAAGTAATTACTGACGGCCTTCCCATCGACGCGATGCCCGCGGTCGAACGCACCGCACAAACCGCATGCCCCTACCTGGGCACCGACTGGGTCGCCGATACCAACGGCCAGCGCGTCACGGGTTACGGCACAGACGAACGCTTTTCGACGCCCTCCTGCGTTTTTTACTCCTACCCCGAAGAACCACAACTCACGGTGATTGTCCGCGATATGGCCACCACGGATGATGCTATCGCGGTAGTTGATTGGGCAGCCCCCATCGATTCCACTGAGCCCGCTGAGGAACCCGCAGGGTGGTCCGGCGGCCGCCGTGGTGGAAACGATACTTCAGGTGCACTCTACGCGGTTCAAAACGGCCCCACCGCGGTCATCGTGTTCACCAATCAGGATCAATCCCTCAAAGCGCAGTTAATCGCTGAGGAAGCAATCCAAAACCTTGGTCTTTAGCTGTTAGAACGCCACATCATTATATGGCATCAATGTGGCCACCCATGGGAACACAACATCCATGAGGAGGAAGAACACCAACACAATGAGCGCCAATACGATGAGAAGTTTTACAAACCAAGGTCCTGGAAGATAGTGCCACAGAAGTGAATACATTTAGTTTTCCTCCAAAGCTGCAGGGCGTTCGCCACTTGATTTATCGATTTCTTCCACCAACATTGCGTGCACAATCATGCGCTCAGCGTTGGAGAACTGCGGGTGACACGTAGTCAAGGTAAGCAGAGCTTCTGATCCTTCACGCACTGCAGTGTCGAAGACGCCCGGTGTTGGGTAGGTGGCATCGATGCGATCCGGAGTGGTGATGCTTCGTCCGGACACATTCACATAGTCACCTTCAGCCATGCGGCTGACCTGGGTTTCGTTGAAGCAATCCGCAGCTTCTGCTGCACGATCTGCACCGTTGGTGGACATTGGCATCACGCGGTACACATCCCAGGAATTGTAAGTCTCCACCACGATCGCATCGCAGACTTCCAGGTTTCCTAGATCATTGAATGGCGCACCCTTGCCCACTCGGTGGCCTGCCACTGCAAAGTTTCCGGCTTCACCAGGCATTTGGGAATCCACATAACGGCCAGGACCGGCAAGAAGGTCTTCCTCATCGGTTCCTTCAATCACTGCGAAGTTGAAGTCAGAGCCGAAAGCTGGAACATACATCCGGGCAAATGCCTCACCAAGTTCCGGGGTGAGCTTTTGTCGAGGATTCACCCGAGCTTCATTCCAGTCTTCATCAAGCTTTTGACCAGCCGATTCTTGTAATTTCCCAGATTCCACGTTGGTCCAATAGGCCTCATAGTATGCGAACAACAAGGCCAAAATGCCTACGGTGAGCAAGATTTCACCAACAACCTGGGAAACACTCAATCGAGGCCGGGGCTTTTTACCATTGCGAGAAGATTCCGCGCTTAACGTGGCTGTCATCGTTACTGTTTTCGTCCAAAATCTTTGTTAGGCGAATCTCAACGTCCTTTTAGGTACCCGTACTTTCAGACACGTACCATGAGACAAGTGCACATGAGATCAATTCATATCTCAAACATTGTACATCTGATCAGCAATAGCGATTATTGCTTGATTGTGTGTTTTTAGATCTTCGGTTCTCTTCACTTAGCTGCTGTGAAGTGCCACCTGTTTGGAAAGGCGAACACGATAGTGCTCGATATTTTGATTTACCCGGTGTCTGGAGTGATGAAGCTGTGGCACCTGCTTCTTCACAACGTTGCGGGTTTGGACGATTCACTGGCGTGGTTCTTTTCCCTTTTCGGCCTTGTCATCACGATCCGTGCAATTATCGCGCCTTTCACCTGGCAGATGTACAAGTCGGGCCGCACTGCCGCACATATTCGTCCTCACCGCGCTGCGCTCCGGGAAGAATACAAGGGAAAGTACGATGAGGCGTCTATTCGGGAGTTGCAGAAGCGCCAGAATGATTTGAATAAGGAATACGGCATTAACCCGCTGGCAGGTTGTGTGCCTGGGCTGATCCAGATACCGATTGTCCTTGGTCTTTACTGGGCACTTCTCCGCATGGCTCGCCCTGAAGGTGGTTTGGAAAATCCCGTCTTCCAGTCGATCGGCTTCCTAACTCCTGAGGAAGTGGAATCTTTCCTCGCTGGTCGCGTGAGCAATGTGCCTCTGCCCGCTTATGTTTCGATGCCCACTGAGCAGCTGGAATATTTGAGCACCACGCAGGCGGAAGTCCTTAATTTCGTTTTGCCACTGTTCATCACAGCCGCAATCCTCACCGCAATCAACATGGCGATGTCCATGTACCGCAGCTTCCAAACCAACGATTACGCATCCGGATTCTCTAACGGCATGCTGAAGTTCATGATCGTGATGTCGATCCTCGCGCCGATCTTCCCACTGTCCCTTGGCCTCACAGGACCATTCCCCACAGCAATCGCACTCTATTGGGTCAGCAACAACCTGTGGACGCTCCTCCAAACAATCATCATGATGGTCATTTTGGAACGCAAATACCCACTTACCGACGATTTCAAAGTGCACCACCTAGAGCAGCGCGACATCTACCGCGCAAAACAAAAAGAGAAGCGCATCTTTTTGTGGACACGACGCAAAAACCGCGCCCTGATGATTCTCACCCCATGGAACGCCTCAACACTTCACGCAACAAACGTGGAACTCACCAAAACCCGTACTGCCGAAATCAACGAAGCAAAACAGGCCCGCAAAGAAATCGCCAACAAGAGGCGCGAAACGCAACGCGAAATGAACCGCGCAGCCATGCAGCGCTTAAAGCAGCGCCGCGCTGAGGTTAAAGCTAAAAAGAAGGGGCTTATCGACGCCTCCCCCAACGAAGATACCCCTTCGGAAAATGAAGAAACTAAATTGAGTAGTCCGCAGGTGGAGCCGACAACAACTGCCGAGCCAAATCGCGAGCCGTCTCAAGAGGACTGATGTTGTGGACCAATCGAGATCCAGCAAGTCCACCATCAAGGAACACCAACAGCTGATTCGCCTGGGTGCTGCCTGGGTAGCCGTTCTTCTCAGTGAGCAAATCAGTCAGAGTCTTATGACACCACTCGCGGTGCTCTAACACTGCTGCAACAATGCCCTTTTCGCTATCAGTTTCGGGGCGAGGGTACTCACTAGCCGCATTCTGAAAGTGCGAGCCGCGGAAATCTTTTTCTGGTTCTTCCTCAATGCACTGATCAAAGAACGCGATGATTTTATCTTCCGGATCCTTCATACCGACGGTGCGCTCACGCCACGCTTCACGCCACAGCTGATCGAGGTTCTCCAGGTATGCAATAACCAGGGCGTCCTTCGATCCGAAAAGGGAATAGAGGCTCGCCTTCGCCACGTCAGCTTCACGGAGGATACGATCAATACCGATGACGCGAATACCTTCTGTGGTGAAAAGGTTGGTTGCGCTATCGAGGAGACGCTGTCGGGGGCTTGGTCGATTGCGACGACGGTTTGCCCCGGCACTTGTTTTACTCTTGCCTGAAGCGCTAGCAGCCACGTTCGGCCACATCCTTTCGGGTTGGTCTGTTTCAAGATACGACGAACTGTCTAACACCAATATAGACAAACCGGTTCGTATAGTTTTAATCCACAGGCAAGTCTAGTGCTTTTTCCACCCCAAAATGACCAAAAGGCCTGTTGATATCGAAATATCAACAGGCCCTACGAATTTAAAGCAGATTACTTCTTCCGAGTGAAGAACTGCACGATCGTCAGCAAAATGACAGCACCAATCAGACATGTGATGAAGCTGAAGATCAAACCGCCACCGGCAACATCCACTCCGAAGACTCCAAGCAGCCAGCCGCCTAACAAGCCACCGATAATACCGACGACTATGTTCAGCAAAATTCCTTGCTGAGCATCAGTGCCTTTAATCTTGGAGGCAATCCAACCAGCTAGACCACCAATAATGATCCATGTAATCCAACCTAGGGCAAGCATGTGGTTCTCCTTTTCTTTCGGTGAATGCTGCCAATTTTAACCAGCTCCGCTCCAAAGGTGTCGACCTATTCCAATTATTCATTGGATTGTTATTAAAAGTTGATGGCCTAATTTCTCGATTTAAGCGCCCGAGTTCCCCGAAGGGCTATGGCCTAGGAATACCGGCTTTAGGCCCTTAGAAGCAATCCTGTGAGGTCAAACTTTTAGGAGTCTCGGCCATGAAATCACCCTTTTCAAGGCAAACCAGACAGGCGTGACAAGATTGGCGAAAAGCCGAAGTTTTGGCACGTGTGTCCGGTATCTCACTGCCTAAACCAGACGGGCGTGCCAAAACCTGGCGGAAATCCAGATTCTTGGCACGTCTGTCTGGCTGCCCTTGGTTTCTCCCTTTCGAATGGCCCGAACTAACCCGCAAACACCAATGCCCCGGCCTCCCTGCACAAAATCAGGAAACCGGGGCATCGAAACTTAAAAGAAACTACTTCTTAATCTTCTCAGGTGAGCGAACCACCATCATTGGGCACGGTGCGGATTGCAGCAGTGCGCGGGAGGTGGAGCCAAGGAGCATGCCCTTAAATCCGCCACGACCATGGGAACCAACGACTAGGAGCTGCGCGTTTTCAGATGCTTCTGCAAGTGCGCGAACTGGGCGGTCACGGGTGATGATCTTCTTGACGGTTACACTTGGGTACTTTTCCACCAGTGGTGCGAGGCGTTCGATCAGCATGTCGGTTTGCTGACGTTCTACTTCATCCCACTGCTGTTGAGCAGCTGCAAGACCTGCAAGTGATGCCTGTACCTGCATGTCCATCCAGGTGTGAACTGCAACGAGTTCGGCGCCACGAGCTTCAGCTTCCGCAAATGCGTATTCGGTTGCCTGTTGGGAGACTTCGGAGCCATCCACACCGACGACGACTGGGCCGTACTTGCTGTCTTCGTTGACTGCGCTGTCCTCACGGACAACAACGACTGGACACTTTGCATGGCTGACCACTGCACCGGAGACGGAGCCCATGACCATTCCGGAGAGTCCGCCGAGTCCGCGGGAACCCATGACGATCATTGTGGCATCGGGAGACATTTCCAACAGCATGTCGATGGGACTGCCTTCAGCGATGGTGTGCCCGATCTTGATTTCTGGCGCTACCTCATGGGCGATGTCACGGGCTTCGTTGATCTTTTCCAGGGCTTCGGCCTGGAGGTCATCGAAAAGCTCTTGTGGTGGAACCATTCCCTCTGCGTAGAGGAACTGAGGCATGGTGTAGCTGGAAGCCAAGCGAAGTGGAATGCCACGTTTGTTGGCGGTATTTGCAGCCCACCGAACAGCTTGTTTTGAGGCGTCCGAGCCATCTACTGCTACGACGACAATGTCTTCAGTGCTCATGTCGGTCGACCTTTCATTGATTGGTGAATCCTGCGTTACAGTTCGTGGAAACTCATGATCTCTAACACCTCTAAGTGTAGCGCGGATACCCAATCCGCACAGCTGGTTAGTACCAGTATTTTTGAGGCTTTTGACACTAATTCCATGCCGTGCCAAGTGCAGCTATGGAGCGGAACCTGACTTCGGGGTCGTAGGAGTAGGTGACTGTAATGATCTCATCTAACTTGTAGCGATCAGCGAATTCCTGCAGTTGTAATACCACTGATTCGGCTGTTCCGATGAAAGTCATTTCCAATGAATCTTCGATGTGTTTCCAGATCATCGGGTCGAGTTTGTCTTTCAGATTCCGCACTGGTGGGGCAAGTTTGCCGCGGGAGTTGGTCACGATTCCGGCGAACATTTGGTGCAGTGTGGAGATCTGGAATTCGGCTTCTTCCTCGGTGTCGCACACCAGGACATTCGCTGCGGCCATGACATAAGGATTGGCTGCTCGTTCGCGATAGGAGGCGATGGCGGGCCCCATTTGGAAGGGTGCGAAGTGGCTGGCGAAGGCGAATGGAAGGTCTAATTTAGCGGCCATCGCAGCGCCATTGAGGGAGGAACCCAGCATGAATAGCGGCACACAGGAGTTTATTCCTGGATGCGCGATGATATTCGGGCGTTCTTCGGGGGTGTCCAAATAATTCTGGAGGGAGACGATTGTGGAGAGGACGTCGTCGACAAGCGAACTTGCCCGACCCAATTCCCGCGCCGTCATGGGGTCGGTTCCTGGTGCGCGCCCTAGGCCGGCCTCGATGCGGCCGGGGTAAATGGCCTCAAGGGTGCCGAGTTCTTCGGCGACGTGCAGCGCGGAGTGGTTGGGCATCATGATGCCACCGGAGCCAACGCGAATGCGTGAAGTGTGGCCTGCAATATGGCCCATGAGCAGCGTCGTCGCGGAAGATGCCAAGCCTTCCGAGTTGTGGTGCTCCGCCACCCAGAAACGCGCATAATTGTGCTCTTCGGCGATCTGCGCAGCGCGAACACTGTGCGCAATGGCCTCGCCGGCCGTCATCCCCTCGCTCAGTGCGACGAGATCAAGCACGCTCAATCGTGGTTTTGGGCCTTCCCCGACTACACTAGACATGTTAAAAACTTATCCAGCATTCACCACTGCGGCATCAGTGTTTGAAGGGAAAAGCAGGTCAAACAAGGTGCGGCTGATTTGAGCGATCACAGCACCGAGATCTGTGCTGAAGAATTCAATGATTGGGTTGATGATTGCGTTGAAGTCCATGTCTAACAGGGTAGTACAAAAGCCAAAAATGAAAGCGCCGCTACCCATCCGCGACGGCCTCAACCCTTCCCGTGTGCGCTTGCCGCTCGACGCAGCGCCGATCCGCGCCATCGATTTTGTTGAATACCTCATTTCCACGCAGCGCCACCGCAATCCGGCCGACAACGCCGAAGCGCTTCAAGCGCGTTTCGACGCCAACCTCGTTGTCAACCACTACGGCGAGCCCTACGCCCCCGACACCATGGTGCAGCCCGACGACGACATTTGGTTCTACCGCATGCCCGCCGCCGAACGGCCAATCCCTTACAAAATTCAAGTCATTCACGAAGACGATGACATCCTCGTCATTGACAAGCCACCCTACCTGGCAACCATGCCTCGTGGCCGCCACATCACCGAAACCGCTCTGGTGAAAATGCGTGTGCTGACTGGAAACAACGATCTCACCCCAGCTCACCGCCTCGATCGACTGACTTCCGGTGTGTTAGTCATGGTGAAAAAACCAGAACTCCGTGGCGCTTACCAAACCTTGTTTGCCCGACGTGAGGCGTCCAAAACCTATGAGGCAATCGCAGAATTCGTTCCAGGGCTACTTGATGATGGTCCCGCGATTTGGGAATCCCGCATCGAAAAGGAACGCGACATCGTGCAAGCCTTCGTCGTGGAAGGCCCCGTCAACGCACGCACCGAACTGGTGTCAGTCACCCCAGTCGACGACGCCGAACAGAGCATCCTCGAAGAAATGCACGGCCCACTCCCCCGCCAAGCGCGCTACGTTCTAGCCCCCTCAACAGGCAAAACCCACCAGCTGCGCATCCACATGCGCGACTTCGCAGCCCCCATCCTCGGCGACCCCCTCTACCCCGTCCTCCACGCAGTCGACGATGAGGACTACACCACCCCAATGCACCTCATCGCCCGCACGCTAACCTTCGTGGATCCTCAAACCAACGAGGAACGTACCTTTGTGAGTAATCGACCTACGGGAAGTTTGTAGGCCTCGTAGACATCACCCAGACGCTCAAGCACTTTTTCAAGCCGGTGTAGTTTTCCCTACACCGGCTTTTCTGTCGTTTCGAGCACTTCGGCCCCATCTTGGCATGTCAGCCCATTTTAAGGCTCTCTACAAGCCCTATAAATCAAAAAAGGGAGTGATGAGGACACACAACCATGTATCCTCACCACTCCCACAACACTTTGTGCTTGTCGACGCTTACCCCCAGGCACAGGCAGCCGCGTGCGAACACCCCTAGAAAACACAAAAGAGAAGAAGCACGAAACAAACACTGTCTGTTTCATGCTTCTTCTCATATATTGTTAAGTTTTTGGTCGGCGGTAACCTACTCTCCCACACCCTCCCGAGTGCAGTACCATCAGCGTAACCAGGCTTAGCTTCCGGGTTCGGAAAGGGACCGGGCGTTTCCCTGCTACTATCACCACCGACACAACCACACACCACACCAACCCAAATGGTTGGTTGTGCTGTGTCAGACACTGCATAATGGACGCGAACACATATTGTTCTGTTTTCGTTACGTTGCGTTACACCAAACCATAAGTGGTTTGTTGTTATCGGTAAATTAGTACCAGTCACCTCCACACCTCACAGTGCTTCCAGATCTGGCCTATCAACCCCATAATCTCTAGGGAACCTCAAAAGAAACCTCATCTCGAAACAGGCTTCCCGCTTAGATGCTTTCAGCGGTTATCCCTCCCGTACGTAGCCAACCAGCCCTGCTCCTGGCGGAACAACTGGCACACCAGAGGTACGTCCGTCCCGGTCCTCTCGTACTAGGGACAGCCTTCCTTCAAGTTTCAACGCGCGCGGCGGATAGAGACCGAACTGTCTCACGACGTTCTAAACCCAGCTCGCGTGCCGCTTTAATGGGCGAACAGCCCAACCCTTGGGACCTACTCCAGCCCCAGGATGCGACGAGCCGACATCGAGGTGCCAAACCATCCCGTCGATATGGACTCTTGGGGAAGATCAGCCTGTTATCCCCGGGGTACCTTTTATCCGTTGAGCGACACCACAACCACAAGTAGGTGCCGGATCACTAGTCCCGACTTTCGTCCCTGCTCCACCTGTCAGTGTCACAGTCAAGCTCCCTTGTGCACTTACACTCACCACCTGATTACCAACCAAGCTGAGGAAACCTTTGGGCGCCTCCGTTACATTTTAGGAGGCAACCGCCCCAGTTAAACTACCCACCAGGCACTGTCCCCAACCCAGATCATGGGCCAAGGTTAAGACATCCAATCCGATCAGAGTGGTATTTCACCAACGACTCACACACAACTAGCGTCATATGATCGAAGTCTCCCACCTATCCTACACAAACCGAATCAAACACCAATACCAAGCTATAGTGAAGGTCCCGGGGTCTTTTCGTCCTGCCGCGCGTAACGAGCATCTTTACTCGTACTGCAATTTCACCGGGCCTGTGGTTGAGACAGCAGGGAAGTCGTTACGCCATTCGTGCAGGTCGGAACTTACCCGACAAGGAATTTCGCTACCTTAGGATGGTTATAGTTACCACCGCCGTTTACTGGGGCTTAAATTCTCAGCTTCGCCTTACGGCTAACCGGTCCTCTTAACCTTCCAGCACCGGGCAGGCGTCAGTCCGTATACATCAACTTAAACGTCTTCGCACGGACCTGTGTTTTTAGTAAACAGTCGCTTCCCTCTATTCTCTGCGACCACAACACGCTCCCAACGAAAAGTTGTTCACACGCCGTGGCCCCCCTTCTCCCGAAGTTACGGGGGCATTTTGCCGAGTTCCTTAACCACAGTTCACCCGAACGCCTTAGTATTCTCTACCTGACTACCTGTGTCGGTTTAGGGTACGGGCCGAATATCAACATCGCTAGAGGCTTTTCTCGACAGCACAGGATCACCCACTTCACCCTTAACGGGCTCCGCATCACGCCTCACACAAAAACAGTGCGGATTTGACCTACACCGCGTGCCACACGCTTACACCACAATCCAATAAGTGGCTGAGCTACCTCCCTGCGTCACCCCATCACTTAGCTACTACCAGATCAGGTCCCACGCAACCACACACCACAAAAAAGCAAAACCTTTTCGCGGCTGCTTATGGGTGGTTAGTATCACTGATTCACCATGGTCGCTCATACTCGGGTACGGGAATATCAACCCGTTATCCATCGACTACGCCTGTCGGCCTCGCCTTAGGCCCCGACTCACCCTGGGAAGATTAACTTGACCCAGGAACCCTTAGTCATCCGGCGGATACGTTTCTCACGCATCATTCGTTACTCATGCCTGCATTCTCACTCGCACACACTCCACCCAAGGTCACCCCAAAGCTTCAACGCATGCACGACGCTCCCCTACCCAACAATCCTATAAAGATCATTGCCGCGGCTTCGGCGGTGTACTTAAGCCCCACTACATTGTCGGCGCGGAATCACTCGACCAGTGAGCTATTACGCACTCTTTCAAGGATGGCTGCTTCTAAGCCAACCTCCTGGCTGTCTTCGCGACCCCACCTCCTTTTCCACTTAGCACACCCTTAGGGGCCTTAGCCGGCGATCTGGGCTGTTTCCCTCTCGACTACGAAGCTTATCCCCCGCAGTCTCACTGCCGTGCTCTGACTTACCGGCATTCGGAGTTTGGCTGATGTCGCTAAGATGTTGGTCCCGCTAAACCATCCAGTAGCTCTACCTCCGGCAAGAAACACACGACGCTGCACCTAAATGCATTTCGGGGAGAACCAGCTATCACGGAGTTTGATTGGCCTTTCACCCCTACCCACAACTCATCCCCTCAGTTTTCAACCTAAGTGGGTTCGCGCCTCCACAACCTCTTACAGCTGCTTCACACTGGCCATGGGTAGATCACTCCGCTTCGGGTCCAAGACATGCCACTCAAAATCACCCTCGTTAGGATTCGGTTTCCCTACGGCTACCCCACACGGGTTAACCTCGCGACATGCCGCTGACTCGCAGGCTCATTCTTCAAAAGGCACGCCATCACACCACAAACGGGTGCTCTGACGGATTGACAGCACACGGTTTCAGGTACTATTTCACTCCCCTCCCGGGGTACTTTTCACCATTCCCTCACGGTACTAATCCGCTATCGGTCATATCAAGTATTCAGGCTTACCGGGTGGTCCCGGCTAATTCACAGCAGATTCCACGAGCCCGCTGCTACTCGGGGTATCAACAACCACACACACCACCATGATCTTCGTGTACAGGACTCTCACCTTCTACGGCAGGTGTTTCCACACCACTTCCACTAACCACGCAGCACATGCCCACATCCGGCAGAATATGGATGTTATTGCCCCACAACCACCTACATGCAACCCCTGCCGGGTATCACACACATAAGTTTTAGCCATCATCCACGTTCGCTCGCCACTACTAACGGAATCACAATTGTTTTCTTCTCCTACGGGTACTGAGATGTTTCACTTCCCCGTGTCAACCTCCACACCAGCTATACATTCACTGGCAGGTAACCACACATCACTGCGGCTGGGTTTCCCCATTCGGACATCCTCGGATCAACGCTTAGTTGGCAACTCCCCGAGGCATAACGCAGCCTCTCACGTCCTTCATCGGCTTGATATGCCAAGGCATCCACCGTGTGCCCTACAAAACAACAAACAAAAAACTATAACCCAACCACCAACAAGGACAAGCCTCACCAATGTTTGGGCGCGTTCGGTATCACACAACAAAAAACAAAAAAATAAAGATGCTCGCGTCCACTATACAGTTCTCACACAACACACCACCGACACCACAACCAAAGAACACAAACATTCTCTACCCGTGTTGACGATGCTCGATGTTAGAAACAACCCACACACACCACACACAGTGTGATGCAAGCGATGTCATTCCAGACACCCAACAGCATGCCACCTATTAATCACAGTATTGACTGTGTTGTTGTCACCCTAAGGGTCATCTCCACCCGATTAAAATAATGTTGATGGCAACCACATACGGGTTCCAACACCAACAACCACACACACAAACAACTGTTTGCCGGTGGTTAGTAAAGCTCCTTAGAAAGGAGGTGATCCAGCCGCACCTTCCGGTACGGCTACCTTGTTACGACTTCGTCCCAATCGCCGATCCCACCTTCGACAGCTCCCCCCTAAAAAGGTTGGGCCACTGGCTTCGGGTGTTACCAACTTTCATGACGTGACGGGCGGTGTGTACAAGGCCCGGGAACGTATTCACCGCAGCGTTGCTGATCTGCGATTACTAGCGACTCCGACTTCATGGGGTCGAGTTGCAGACCCCAATCCGAACTGAGGCCGGCTTTAAGAGATTAGCTCCACCTCACGGTGTGGCAACTCGCTGTACCGACCATTGTAGCATGTGTGAAGCCCTGGACATAAGGGGCATGATGATTTGACGTCATCCCCACCTTCCTCCGAGTTAACCCCGGCAGTCTCTCATGAGTACCCACCACAATGTGCTGGCAACATAAGACAAGGGTTGCGCTCGTTGCGGGACTTAACCCAACATCTCACGACACGAGCTGACGACAACCATGCACCACCTGTGAACCGACCACAAGGGAAAACGTATCTCTACGCCGATCCGGTCCATGTCAAGCCCAGGTAAGGTTCTTCGCGTTGCATCGAATTAATCCACATGCTCCGCCGCTTGTGCGGGCCCCCGTCAATTCCTTTGAGTTTTAGCCTTGCGGCCGTACTCCCCAGGCGGGGCGCTTAATGCGTTAGCTGCGGCACAGAAGTCGTGGAAGACCCCTACACCTAGCGCCCACCGTTTACGGCATGGACTACCAGGGTATCTAATCCTGTTCGCTACCCATGCTTTCGCTCCTCAGCGTCAGTTACTGCCCAGAGACCTGCCTTCGCCATTGGTGTTCCTCCTGATATCTGCGCATTTCACCGCTACACCAGGAATTCCAGTCTCCCCTACAGCACTCAAGTTATGCCCGTATCGCCTGCACGCCCGAAGTTAAGCCCCGGGATTTCACAGACGACGCGACAAACCACCTACGAGCTCTTTACGCCCAGTAATTCCGGACAACGCTCGCACCCTACGTATTACCGCGGCTGCTGGCACGTAGTTAGCCGGTGCTTCTTCTCCAGGTACCGTCACCAAAAAGGCTTCGTCCCTAGCGAAAGGAGTTTACAACCCGAAGGCCGTCATCCCCCACGCGGCGTCGCTGCATCAGGCTTGCGCCCATTGTGCAATATTCCCCACTGCTGCCTCCCGTAGGAGTCTGGGCCGTGTCTCAGTCCCAATGTGGCCGTACACCCTCTCAGGCCGGCTACCCGTCGACGCCTTGGTAGGCCATTACCCCACCAACAAGCTGATAGGCCGCAGGCTCATCCCACACCGCACAAGGCTTTCCACACCACCCCTACGGTGGTGTGAATATTCGGTATTAGACCCAGTTTCCCAGGCTTATCCCAAAGTGTAGGGCAGATCACCCACGTGTTACTCACCCGTTCGCCACTCATCCACCAAATGCAAGCATTTGGTTTCAGCGTTCGACTTGCATGTGTTAAGCACGCCGCCAGCGTTCGTCCTGAGCCAGGATCAAACTCTCCACAAAAAAACAATTAATAGATTGTTTAGGCCGTGAAAAGCCCAACACCTGACAAAAACAACAACACCCCCACCAACCATCAGAAAATGATCAGATAATGGGGTGTTACTGGCATTATCAAAAAATAATGATTCTAAAAAAACACCACAATCCACATAAGGATCATCGTGTCTTTCATGTGGGCCTGATCCCTTGACGGGGAACAAGCAGACCCACAACATCATGCCAACAATAAGATTATTGTTTACAGTGATGGATAAATATTGGCAATCCACCACCCGGCATGACCCACCACACATCACCCAAGGTGATCTGTGGTAGTGACAAAAATAATAAATGGCACACTATTGAGTTCTCAAACAACATACGCACACCATAAGATCATCAACGTTTGTTTGTTGGTGTCTTGTTGGCAGCTTGTTCAACGTTACTTCATCTTGTTTACTTTCACCAAATCGGTGTTTGTTGACTTCGATGAAGTGTTGTTGGTTTGTCGAGCGTTTGTTTTCCTAGATCCGCCTCACTGTCCACATCATTGCTGGTGTGTTGGGGCGTTGTTGGTCGCGCTGACTGGAATTAATTTACACACCCGCCCAACAGTCCGCAACCCCGCAGGTCAAGAGGGTTTAAGCGCTACTTGTACAGGCCCCTACTTTCAGCGACCTGGTCTAAAAGGGCGTGAATGCGCGCACGAGTGAAACCAAGGTGGATGGATTCGTCGATAAGCGGTGCTACATAAGTAGCTGCGAAGGCGGCATCTCGCCGCTCTCGGATGAGTGCTGGGGCCTGGGCGCTGACGAACATGCCAATGCCACGCTTTTTATAGAGGATGCCGGCTTCGACAAGGAGGGTCAGGCCGTTGCGTGCGGTGGCGGGATTAATGCGATGGAACGCGGCTAGTTCATTAGTAGAAGGCACGCGTTGATCAATGCTCAAGGTTCCGTCAACGATGGAGTCCTCGATCAAAGAAGCGATCTGTTTATACAGAGGCGCCGTCACGACGATCCCGATGGTTGGTTACTCATATAACTAACCCTATGCCTCTTTATAGTCATTAAAAACAGTATTAACGACATTACTTTCGGGTAATACCAAGTGTTATGCAGTCTCTACCCACTTAAAATGGACGCATATTCGCAAGATAAGGCATGCTTAGATGAATAGATTTTAACTCAACGTTTACTAAACAGAATCGGAATTAGGAGCCATGCTTGAACGCACACAGGTATTCGTGGATACGTCCTACCTGCTCGCAAGCTTTTACAACTCTTGGGAGACAGGGGCACGTGCCCAATTAGAAATCGACCTCCCCGAAGTAGTCGGGGTATTAGGAAGGATGATTGAACAACAACTTAAACAGCCAGTACAACGCCAAATGTGGTACGACGGAATCCCCGATTCCGGCCCCCACCGCTATCAACGAGCACTACGCACCTGCGATGGTGTGCAACTTCGTGCTGGCCAATTAATTGAATGGGGCGAACGCCGCACACAAAAGGCAGTAGATACCCGCCTTGTTGCAGACCTCGTTCTCGCAGGTGTTCGCGGACAATGCTCCGATATCGTGCTCGTCAGTGGCGACGCCGACATGATCCCCGGTGTTCAAGAAGCTGCCAATGCAGGCCTTCGCGTTCACCTCTACGGCTTCGGCTGGGATTCCATGTCCTCCCAACTGCGCCACTGCTGTGACACCACCACCATTTTGGATCCTCGAGAAGATTTTGCTGAATGCATGCAGCTGCAGGTTCTCGAAGGTCCACTACCCCCTGTCGTTCGAGTAAAGCCCATCAACGATGCAGAACCCATCGAGGATTTGGATTTCACTCCAGTTCCAGGCGTCGCCTCACCATTTGAAGAGGTCAGCGCGAAAGATGAGAAATTCTCTCCACGCCCAGGTGAACCTGCCGAAGCTTTGTCGGAACAGGTCTGTGAAGCGCAGAATGAGATCTCCAAACACGAAGGTCAAACCGCTGATTCAGTAGAAATCACCGAGTCTTTCGAGGGCGCTGAAATCAAGGTAACTGAGTTTTTTGGAGAACCAGCTGTTCCAGTAGCGGAATCAGGCGTAGAAGCTCCCACGGTTCCCGAGGCAGCTAAGCCCACTCCGGCGAAACCTAAGACTCCAAAGGCAGAGCCCCAAAAGCAAGAATCCCCCAAGCCGGGAACTCCAAAACCAAAAGCTCCAAGCCCTGCGGATATTCCACCGAAAGCCCCAGCTGACACTGAGGAACATTCGGAAGTCGAAGCTGAAATCGAGGACTCACGTCCAAAGATCCCCAGCCCTTCGATGATGGCTCCCCGCCGCAAGCTTCGTTCCCGCTACGTTCCGCTTCCCAACGAAGTGTGGGCAACAGCAGGATTCCAAACTCCTTACGATGTCGGGCAACAGTACGCATCGTGGTGGTTTGAAAACGCAGCTACCAGCACTCAAAGAGATCAGGCTCATCTATTGTCTGGTGGCGGACTTCCACCAGAGATCGATCGCCCGCTTCTGCAGTTTGCTTGTGAAACTCTCCACGAATACACCCTGACTGAAGCGCAGCGCGTAGCTTTACGCGATGGCTTTCACTCAGGAATCCGTGGAGTATTGCTCAACCAGCGAGATAGCTAGAATCACAAAAAACTGGGGCTAATTCCTTTCGGAGTTAGCCCCAGTTTTTTGTGTTTAGATTATTTCTTCTCGGACTCGTCTGCGGACGCTTCTGGAGCATCAGCTTCTGGGCTTGCGGTTTCTGGGGTAGCTGAAGGGGTGGAGGTTTCGTCGATAAGCTCTTCCGCATCCTCGACACCTGCCTCTAGCTGGCCCTTAGGCGTTGCGGACGTGCCCAGCTCCTCCGCGCGAAGTTCAGCCAAACGAGCTGACGCCCGCATATCGGTGCCGGACTGCGCAATCTCAGCCATGCGATCACTAACAGTGTTCTGGGTAAGTTCCTGCGCGCCCAAAGCATCTGCGTATCGACGCTCAATCTTCTCACGCACCGCATCAAGGGTAGGAACAGAAGAATCCTGAGTGCCAAACTGATTCAAAGAATCCATAGACTTAGTGACACTTTCCTGCATCTTCGCCTGATCAGCCTGCGCACGTAGAGCATCAATCTGAGACATCTGCTCTTTCAGGCGCATCTCAGACTCTTTAGACTTCGCAACAGCATCCTTCGCCGCAACCTCAGCCTGCTGATGAAGCGCAGTAGTCTGCTCCAACTGCTGTTCCACAGCTACCAACTGGGAAGCAAAAACCTCAGCAGTGTTGTTGAACTCCTGAGCCTTAACACTGTCGCCTTCGTTTGCGGACTTATCTGCCACCTGAATTGCCTGACGAGCCTGTTCCTGCAACTTATCGCGGTCAGTAACCAAGCGGTTCAATTTCATCTCAAGCTGCTTCTGCTGACCGATAATCTGAGAAGCGTGCTGCATAATCTGCTGGTGCTGCTTCTGGGCAGCTTCTGTAGCTTGCTGAATTTGGATCTTTGGATCTGCATTCTCATCGATCTTGTTGTCGAACGATGCCATGAGATACTTCCAGCCCTTGCTGAGCGGATTAGCCATTATCAGTCACTTCCCTGAGGTTTTAGTTACGTGTGTCTAAGTGTGTCTAATTGAAAAATCATTTCTGCGCCCGCAAGCAAATCACTGAATCCGATTCGCTGCTCAGAACCCGAGTCTACGCAAAACTGCACTCTGCTGAACGCTCATTTGAAAAAATGGGGGATGGTTCGGGGTCTTCATCAGGGGGTGAAGGTGGTGCGCCCTTAGGTTTGGAGGGACTTCGTAAGATTCCGGCTTTACTTCGGGCGTCACTTCAGGCCTGTATCGCCAGTTTTGGCCTTGGCGCCCGCGATTTCGCCCCAGACGACCTCAATTCAAGGGGGTCAAATCCTAAAACCGGACTAAAACCGGACTAAAACCAGACTGTAAAGTGTCAGCACGTTGTGCACACTCAATATCATATCCTTGCGCACGCCCGATCCCACTAGGTTGTGCACACACAAAGCCACAGCAGTGTGCACACCAACCCTCACCCTCGGGACAAGTTTCTAGCGCAGTAGATCCCCCGGATCTATCGACTTGAATCGCTTCTCAGCCTCATTACGTTTGCGTTGCCACAACGGTGTCGGGTGTTGCATCCACACCCCACGAATGTTGTAAGAATTGATATACGACTTACCCCGGGCAATCGCCACAACCGGCAACGGAATCGACAACTCAAGCTCCCCGGTTATCGCATCCCAGAAACCAAGCTCAGTTGCCGTCACCGTCCGATAAAACTCCCTGTCCCTCATCGTACGAGGAACAGAAATACGCATCCCCTGGAACACCACCTTCTGATTATTCCCAGCAAACGTAAACACATCAGGATCCACCGGCTTTTTACCAAAACGACGTACCCGTCGACGTTGCTCGGTCTGCTGCATCTTAGACACCGGAACAGATTCCTCCTGCCGAACAAGCGAGACATCTGATTGCTTCTCAATTCGACGACGGGCATAGTGATCGGCTTGCTGTTGAAGCACGACGGGATCAATCGGGGGTTGTTGTTCCACACAGCCCACAATCTCCCAGGCCGAGGCCGGGGTGAGATTATTCGGCAACCCCTGATGCGGGCGACGATTGTTGTAATGATCGCGGAACTGTTCAATATAGTGCGCACATTCCTCAAGTGTGTGTGGTTGATGAGCTTGAAGGAAACGAAATAGTGTGCGGTGGCTGCGTTCGTTTTTACCTTGGGTTTGAGGATGCCCAGGCTTGCCGGTAATGCTTAAACACCCCACCGTCGCGAGATAGCTTTCCAAGCTTCCGACGTATCCTTGCCGCATCCGGTTAAACGCTGAGCCGTTATCACTGAGTAATTCATGCGGGGCACCGAAATGAGCAATCGCTTGTTCTAGCGCTGTTCGGGCATCGACTGAGTTTTCATTCGCGGGGAAGACACAGGTTCCGACATCAAACCGAGTGGCATCATCAAGGATTTGATAGATCGTTACCCGAGTCAGATCAGTATCGTGCAGTGTGTAGATGAAACCATCTATTTGCCACATTTCCATGGCTTGACCTCGTTGAAACCTCACCACCGACGACTTCGGTCGCTTCTTAGGGTTACTTTCAACAGCTCCTGCAGCGCGTAACAAGCAAGCGATAGTTGAGACGGATGGAATCGGTGCAGTCAGTTCCCCGGTGGCGATGCCTTCGAATCGGATAGAGATCGGACCGTATTCCCATCCTTGGGCTTTCAGGCGGTGCGCGGATGGCCAACAAGATACTGGTGATGGATTCATCGTATGTTCGCCGGGAGGTGATCGGGGCGCTGGAGCGTGGATGCAGCGCTGCACTGGCATCTTGTTGGTATCGGTTGCGGATGTTGTAGAAGCTGCGCCGCGATATTTTAAGCCGACTGCAGAACTCTTCGATCGAGGGACTGTTCGGTGCGAACAGATCGAAATCGATGATCTTGCATCGGGTTTCTGGGGGCAGGGGTTTAGGCATGATCTCAATTGTGAGCAGCCGAGGACTATGCCTGTGGTGAAGGTCTAGGGTGTGCACAAGGTCATGACACAAAACATCACGTAACCGCACCCCTGTCCACCGGGCGGTAGCTGACCAGCCCTGCATGCACGTGTGGACGGCGACATACGAGGTCTGCGGCAGCTCCCGCAGATCGTCGAGGGTGATGGTTTTCTCGGTGCCGTTGGGATCGTCGCCGAGGGTGATGGTGTATCCCTCCCACTCGTTGTCGCGGGCGGCGATCCACTCGGGGGATTCATCATCGGTCGGCGGCAGGCCATTGGTCCAGTGGAACTGCGAGATGTCCTTGTCCGTGTAGGTGTTCTGCCTGCTCATCCGGGGACGCAGCCGGTTGAGGAAGATTTTGCGTCCGATCTCCGTGATGCTGGCGGTGAACCGCTGGGCGCGGGCCCGGTCAGCCAGCGACCAATAGCTGAGCACGATCCAGAACAACACCACCATGACGATGGTGGTGATCACGATGATGTAGGCCTGCGCCGCACGGTCAGTGTTCATATCGCCGAAGACCATGTGGACCATGTTGTAGTCGCCATGGACCAAAAAACCAGGCCGACGTGCATGATGACAAAGCCTGTCATCAACACCATGGCGATGAAGTGCAGGGAACGTGCACCCTAGTGGCCGCCGAAGAGTTTGACGTACCACGGGAAGCGGGACCGGATGGCCGGGGCCATCGCTATTCCGGTGAGGATGAGAAACGGCGCCAGGATAAAGATGACGAAGGTGTAGCCCAGCATTTGCAAGGCGTCATAGGGGGGTGAAGTGCTCGATGCCTGGGGCACGAAAGCCCAGGTAAACCTTCAATGTCTCCCACGCCTCGGGGAAGACGTCCCAGGAGGTGGGGATAATGCGTTGCCACAGCCCGGTGGCGAACAGCAGAACGACGTAGACGATGCCGTTGAGCACCCGCAACATCGTCGACAGACCGTGCCAGTGTCGGCCCAGGCCGATGTTCTCCCGACCCGGCAGACCGATCAACGGGGAAAGGGACTTCTCGTCCATCAGTGAGGTGTAGACCCTTCCTCCTTGGGCAGTTTGCATTTGGTGAACCGGAGCCATTCCGTGCCCGAGGCGCAGTCATTGCGCCACCACAACCGCGGCATGGACGACAGAATCTCCCAGCCAGACCGCAGCAGCATGCCGATGAGAACGAAATTGATCAGGTGTGTGGCCCGCAGCCACAGGGGGAAATCTGGGTTGATCTCCACGGATTACTCCTTAGATCGTGACCGTCAATAGCTACATACAATGGAAAATTACGTATAATGCGTCTCACGCTAACCTGATAAGAAAGGAAAAATAAGGGACAATCCCCGCAGAGGGGGTAGCCAAGCGGTGTCAGGAGCAGTGCCCGAGACGCCGTGCCATCGACGATGGCTCGCCTTCCCCGATGCTGTGTCGTCCTACAGGCCGTTAGAATCCAGACTCGCGGGCACTAGCCGCGCGACTGCCGATAACCGCACGCCGTGTACCGGAAGGCTTGGAACGCCTAGGGTGTTCCTCATGGCAACAGATGACGTTAGCAAGGCCTACAGCTCACCGACCTTTGATGCGGAGGCACTGCTCGGAACGGTAATCTCAGCCGAGGACCCCGACCGCGTGCTCATCGAGCCCTGGGAGACCGGCGTCGACGGGGTGATCCTCGATGTGGGCTCTGGTACCGGGCGGTGGACCGGTCACCTCGCGAGCCTCGGACACCAGATCGAGGGACTGGAACCAGCGACACGGCTCGTGGAGCTCGCTCGTCAGACACATCCCTCAGTGACCTTTCACCACGGCACTATTACCGACCTCTCAGACTCGCCGAAGCGCTGGGCAGGCCTGTTGGCCTGGTACTCCCTGATCCACATGGACCCGGGCGAGCTGCCCGACGCCCTGGTCGCACTGCGGATGGAGGTGGAGGATGGTGGTGGCCTGCTGATGTCCTTTTTCTCCGGGCCTTCTCTGGAACCGATGTATCATCCCGTGGCCACCGCCTACCGGTGGCCACTGCCCGAGCTTGCCCAGGCACTGGAGACCGCGGGTTTCCAGGTCACCAGTAGTCACTGGGATCCTCGGTTCCCCCATGCCTATCTCACCGCCGAGGCCAGCAAGCAGAATCTCGCCTGACAGTGGTGGCCTACTCGGTAGTCGTCTTCTCAGAAAACATCTCATAGCACCAGTGTGGTTACCTGCCGGAGGAGAAACGAGTAGTCAGCCGGACCATAACTGGCGACCGCCTGGGGCAGCGGTCCATCCAGGCCCCGGATGGTCTGCAAGGAGGTCGGCGCCGATCACTTCCTCCAGGCGTCGACGAAAACGCCCAGCCACCACAAAACCCGCATTCCCCCTTTTCTGTCCCGAGGCACCTCAGACTGCGGCCCCGAACAAAACACCGACACCGTAGGTCAGGGCCAGGCCGAGGGCACCACCGATCACCAGGCGCCCGCACGCGCGCATTGGGGAGGTACCCGAGATCTGGGCTGAGATGAACCCGGTCACCGCCAGGACCAGCAGCGTGACTACGAAGACCACGCCGGCGTCCCAGCCTGCAGGGGCGATGAATACCGACACCATCGGCAGCAGTGCTCCGAGCAGGAAAGCCACGGCCGAGGAGAAGGCGGCGGCCAAGGGGCTGGTCAGTTGCTCATTATCAATACCGAGCTCGAGCTGAAGGTGGGCGCCCAAGGCGTCGCCCTGCCCGATCTCGGTGGCCGCCTGGTTCGCAGTCTCAGGGGAGATGCCGTAGGAGTGTAGGATCTCCGACAGCTCGACGTGCTCGGCCGTCGGGTCTTCGGCCAGCTCCTTCGCTTCTTTTGCGATGAGCACCCGTTCGGTATCACGCTGTGAGGAGACAGAGACGTACTCACCGAGAGCCATAGATACCGCCCCCGCGATCGTTGAGGCCAAACCAGCGCCGAACACGACGGTGTCACTGGCGCCGGTGGCGATCACACCGAGCAGTAGCGCAGCAATGGAGACGATACCGTCATTAGCACCCAGCACACCGGCACGCAGAGTATTCATACGATTGTGGTGGCTGGGTACGTGCGGTTCGTGCAGGGGGTGAGCGGTGTTAGTGGAGATGATCATCAGTCCTTTATCGGTGCAGGAGACCCTATAAGCACAGCTTATTAAGGGCCTAGTTTTCCCACAACGAAGCAGAGCCAACCCTCGCCGTCTTTCGGGGCTAATCTCTTCGTTGACACGTCCCGTTACTCTCCGGGAGATCTCCTGGAACGTGGACTCCGGCCTCGAGATGCGAGAAGAGGCACCTACTCATGCTCAAGCATGCGGTAGAGGGGGGCCGGTTGACTTTGTCCTCGCGGGCGACCTGGCCCTTGGGTACGTGGGCCACGATCTTTTCCATGATCACCTGGGGTTGCTCGTTATCGAACTTCGTGCCCCTGATGTTGTTAGCGGTTGGCCGCCTTAACCAGGTCGATACCCTCGGCCTGGCACTCATGGATCCGATAACGCTCGAACTCCACGAAGGGAGCCGAGGAGGGTGAATTACTCCTGGAGATCACGTGGAGAAGGTGAACCGGATCTCCTTCGGCATGATGTGGACAGCCTTAAACTCTGGGTCTGCCACGATCTCGTGCCAGATATCAGCGGGAATGACGAGGCTGTCTCCCGCGCTCACACCACGGTCTTCGGCAGAGAACTGAACGATGCATCGCCCCTCGGTGACGACGAGCACCGATTCGGTTGATGCTCTGTGTCTGGGCCAGGAAATTCCCGACGCCGCTTCCATCCGTTTAGTTTCAAACAGCGCTCCTTCTTCTAACAGCGTCACCCGGGGTCGCCCTGCGGATTCCATCGTAAAACTCCTTCGCCACACGTCACTCACTGGAGGGAATCTAGTCCCCGACCTGCCATGCCGCCACCCTACCGGCACAGGTCATGAGCGATGAGAATTAGTCCTTATCGTTATTGGATAGCGCTCGGTAGAGGGTGGCTCTGCCAATTCTGAGGTCTTGGGCGATCGACACCTTGGACTCACCAGCTTCTACCCGTTTCCGGGCTTTCTCGACGTCGTCCGGGGTGAGGGCGCGTTTGCGGCCCTTGTACTTGCCGGCCTTTTTCGCCAGGCGATCCCCTCGGCTTGGCGCTCCCGGATGATGGAGCATTCGAACTCAGCGAAGGAGCCGAGAATGCTCAGCATCAGCTGGGCCCGCGAAGCATTGGATTCCGCCGAGAAGATCAGGTTTTCCTTGATGAAGTGCACGCTCGCACCCTTGGCGGTGATTTGGTCAATGATCTTCTGCAGGTCGACCTTCGACCATCACAATGACAGGCCAGGAACAACTATTGGTACGAGGGACATGAAACATCGCAGTCAGGTTCTCCTTGTTTAGGGCCGATATCAGGCCCTAGTTCTGGTTCTGTGGCGGCAGCGCCGCGATGAGCTGGGCGTCGAAGTCCTGCGGACCCAGGCTGGCGGCACCGCCTGGCGAACCGAGGTCGTCGAAAAAGGCGGCGTTAGCGCCGGTGTAGTCCCACCATTCGTGGGGAACATCGTCTTCGTAGAAGATGGCTTCAACCGGGCAGACGGGCTCGCAGGCACCGCAGTCGACGCACTCATCGGGGTGGATGTAGAGCATCCGTTTGCCCTCGTAGATGCAGTCCACGGGACATTCCTCGACGCAGGCTCGATCCAGGACATCAACGCAGGGCTGGGCGATTGTGTAGGTCATCGGATCTCCAATACTACGGATAAAGACGTGGAAAATAGGTTCACTGTCATCCTATTAGCTCCCCGACCCTTCACCAAGGGGCACATATTTTCGATTATCCCCGCCACCAGTAGCGGTAAGGATAGTGGAACCGGTCAGCTGGTCACCGTCGCATGCTGGTACAAACATCAGGGGCAGGAGGCCGGTGATCGAACGGTGCCGGTCCATGGTCTCGCCGCGGAAGACGGACCCTCGGCGGGCTCAAACACCCCAGGGGAAGTCCCTATCTTTCTTATTGCGTCAGTTTGGCAATGGTGATCAAAACAGCGGAGTCCTCGATTGCTTCGAGGCTGTGCCGAGATCGCGGCACGATCAACAGATCACCGCTGCGACCTATCCAGGTCTCATCGCCCGTCCTGAGTTGGACACGCCCTTGTAGGACATAAATCGTGGATTCATCGTGATTGTCGCGCTCTCCGAGCTCAGCACCCTGACGTATCCCGACGACGGTCTGCCGCAGAATTTTTTCGTGCCCGCCGAAGACGGTATCGGCGGCACGAGCACTAGGGGCGGCGACGGCCTCTTTAAGTTGCTTGCGGGCGAGGGCCTCGATCGATATTTTGTGCATATAAACAACCTTTCGGAGCCGGTCTGGGAAGCATCGAATGGTGAGGAGACGATGTTTTTGTTCATGCGCCTTCCCTGATGACCCGAGAAGTTAGCGCAGTACGTAAAAAAGTGGACTCTGACGTGTCAGTGGTAGGGATCCTCCGTGGGCGGGCCGATGCGCAGGATAGCGGTCAGCGCTTAGTTTCGGTCACTGACATCGAGATGGGCGGCGATTATTCATGAGGAATGCAAGTTAATTGCAGCATCACGCGACGAGTCAACTACATCCGACCCATTGCGCAAGCTCTTCGATTGCGGTTGATCGTGATGGTCAAAACCAGCGGCCGGTCAGGGATCGCTCTTTGCCACACGTCAGGGACTTAAGCTCGTCAGTAATTGTTGGCGGCGGCGACGGTAGCGAACTCGATGGCGACGACATGGCCGGCCATGGTCAAAGAATCCGCGTTCGTGGCATAACCCGGTCGTAACGTCTCTCGGACTTCGGCATCTGGTTGGATTACTCCGATGGTCTTCCGCGCGGTGCTGTTGCAAAGTTTGGGCAGTAGGAAGAGCGACGTGAAATAATCACAGCCATGGGTACCTTCTCCGGTCGTCATTTCCCCCGTGACATCATTTTGTGGGCAGTGCGCAGGTCACTGCCGCTACGGGGTGAGCTGACCTAAGATCTGGAGGAAATGATGACTTCAGCAGGGCGTGCCGGTTGATCACACCACGATTCTCACCGCTGGGTCCAGACATACGCCCCTGAGCTGGACAAGCAAACACGGTGGTACCGGCAGGTACCTGACTGGCAGGCCCGGTCCTGGCGGGTGGATGAGACCTATATCCGGGTACGGTGTCATCGGTAATCGGTGGTGACGTCGCTGACCCCGAGGAGTTCCATGTCCTCCTGGGCTCTCACCGCGTCGGCTACACGTTTACCGATGACACCGTACCCGTTTACTGGCTCTTCCTGTTTTAGAGTGCATTGATCTTATGGACCAACTGCCCTGAATGGATAAGGCACCGCAGAATGTAGTGGTTCAAATTACGGAAACCTAGAGCAATCCCACGCAAATGCTCCAACCGTCCGTTGATCGCTTCGACCGGACCGTTGGAGACACCAACATCGAAATACGCCAACACATCACCAAGTCGTTTAAACAAACTACGACCCAACTGCGCGAGTTCCTTATTCGGCCCCTTCAACACCCGAAGCTGATCAATAATGGTCCGCATTTTCTTCTTCGCTTCACGCTTATTACCCATCTGATAACAATCAATAATCGCCTGATACGCAAGCCACGCAAGCTTTAACACCCCGTAGTCTTTGTCATACGCCCACAACTGCTCCAAGCTTTCTTGCTGACGAGGACTCAACCACTTGTGCGTGGTCAACAAGGTCTTCCGGTTTTTATACAACGGATCCTGGCTTAAACCACGACGCTGGTATTTCTCCCGCTGGAGGCGTTGCCGGCAGGCGGTGAGCTTATCACCAGCAAGCCGCACAACATGGAATGGATCCATCACGCGACGAGCAGAAGGAATGAGTTCTTTACTTGCTGTGGCGTAGCCTTGGAACCCATCCATAGACACGATACGTATCTGATTGCGGAACTGTTCACCGCGGGAACCAAGCCAGGACCGTAAAGCATCAGCACTACGACCTGGGACGACATCTAATAACCGGGCAGGACACCGTGAGTCATACCGATGCCCGGTCATATCGACAATCACGGTGACAAACCCATCACCATGCTTAGCCCTATTATGTGACCACTTATGCTCATCCACCCCAATGACATACACTCCATCAAGATGGTGAGGATCGTTATAGACCAGCTCACGGCACATATCGAGGGCTAGTTGGCAGGTTAAATCCCACCCTAGCCCAAGTGCTTTCGCGGTTGCGTGAACACTCATCCGGTCAATAGCAAGGCGTTGTAAAATCCAGCGGGTGACCCGGTGGGTGACCTTTTTACCGTGGTCAGCGCAGCTTAGTTCTGCTTGGAAATACTTTTGCTTACATGTCGGGTTGGTGCAGCGGTAGCGAGGTAGACGGATAAACAGTTTGGTGGGAAACCCGACGATGGGTAAATCAATGAGCATCCGGTGGGTGTGATTACGAAACACCCCAGGTTGGAAGCATTCTGGGCAGGTGGAGGTATAGTCGAGTGCGTCTGCTTCGATCAGGGTGTAATCACCTGCATCGGAAGCGCCGGTGATGGTGAGTCCTAGTTCCGCAGTGCGGCAGATGGTGTCAGCGATGATGTTGCCGGTAGACTACCATGGGTAGAGCCTTTTGTTGGTGTTTGGTTAGCTTAGATACCTAAACCTTAACCCTGACAAAAGGCTCGTTTATTTTCGGGTCTACACCGCTAGCCCAGGTTCTGTGATGTACCCCAAAACCGGAAGGGCCCGTTTACTGCAACCTTGATTTTATTCGGCATGCTGATTGTCCTTCCCGGAAATCCTGGTTTGGCCCGATGGTCGTATGGTCGTGTTTCTCATCTGGGGTGGTCGGGGAATGTCCTTGTTCAGAGCTCGTTGAGCATCTGCTCCATCTCGGCGATCTCGGCCTCCTGATCTTCAATGACCTGCTCAGCCAGAGCGATGGCCTGCGGGTTCTGGCCATCAGTGACCTCATCGCGGGCCATATCGACCGCGCCCTCATGGTGGGCGGTCATCTGCTCAAGGTAGAGCCGGGCAGCCTCGGTGCCCTGGGCGTCCTCGAGGGCTGTCATGTCCTCCTCGCTCATCATTCCACTCATCCCGCCATGGTCCATCTCACCCATATCACCGGTGACCGGATCTTCTTCCCAGGTCTCGAGCATGGTATTCATCCGGTCGATCTCCGGGCCCTGGGCATCGATAACACCCTGGGTGAACTCGATGACCTCGGCCGGGATATCGTCCTTGGCCAGGAGGATTTCACTCATCTCCACGGCCTGTTGGTGATGCGGGATCATCATCTGCGCGAACATGATGTCCGCGTCATTGTGCTCGGCGGAGACCTCTCCGGCCGCCCCCGTCTCTGTCTCAGGATCCGTGGTGGCCCCGGTCGTTTCGGTGGTGTCGGGGGCGGACGTAGTGGCGATGGTCGTGGTGTCGGTGTTTTCTCCCTCAGTGTTATCTGCGCAGGCGGACAAAACCAGGGTGGAGGTCAAGGCGAGAGCGGCGATGGTGATGGTGCGCTTCATGGGGGTTCCCTTTCGGAGGTTGTGTATGGGGGGGAGTCGATGAAGGATTGAAAGTCAGCGGACGGTGGCTGCAGAGCTCACAGCAGCCTTCTCCTCCTTCCCGTCGGTCGGAGCTAGGTGAGCCGGGTCCAGGTCGATCCGGCGTAGCAGCTGGGCGTTGAGGGCGACGATGATCGTGGACAGGGACATCAAGATGGCGGCGGCCGCCGGGGGAAGCAGCACACCGATGGGGGCGAGCACACCGGCGGCCAGGGGAACGGCCACGATGTTGTACCCGGTCGCCCAGACCAGGTTCTGGACCATCTTGCGGTAGCTGGCATGGGAGAGCTCGATCATCGACAGCACGGCCCGGGGATCATCACTGGCCAGGACCACCCCGGCGGACTCCATCGCCACATCTGTACCCGCGCCAATCGCAATACCGACCTCGGCCCGGGCCAGGGCCGGGGCGTCATTGACACCGTCGCCGACCATGGCCACGCTCAGACCGCGCTCCTGCAGCTGGGTGACCTTGGTGTCCTTGTCCTGCGGCAGAACCTCGGCGAAGACCTCATCGATCCCCAGATCCTTGCCCACTGCCTGGGCGACCTGGGTGGCGTCACCGGTGATCATCGCCACCTTCACCCCGCGGGCCTGCAGGGCGCGTACCGCCGCGCGGGATTCGGGGCGGATTTTGTCCTCCACTGCCACCGCACCGATGATCTCACCGTCGCGGACGACGTGGAGCACTCCGGCGCCTCGCTGTGCCCAGGAACCGGTGATGTCGGCGAGCTCACCCGGGGTGGTCAGACTGAATTCGCGCAGCATGTTCGGCCCGCCCACGAGGATTTCGGCACCGTCGACGGTGGCCCGGATCCCGCGGCCGGAGGCGGCGGTGAAACCGGTTGCGCGCAGCTGACGCTGCGAGGCCTCCGGGTGTGCGGCCGCGGCAGTCACGATCGCGCGGGCCACGGGGTGCTCACTATCGGCCTCAGCGGCGGCGGCCAGGGCCAGCAGCTCACCCTCGGCGATACCCGTGGCCGGAGCCACGCCGGTGACGGCGTGTGCGCCTTCGGTCAGGGTGCCGGTCTTATCGAACAAGACGACATCGATGGTGCGCATGTGCTCGAGTGCCATGCGGTCCTTGATGAGCACCCCGGATTTCGCGGCGCGCTCGGAGGAGATCGCGATGACCAGCGGGATGGCCAGGCCCAGGGCGTGCGGGCAGGCGATGATCAGCACGGTCACGGCGCGGACTACCGCATCGTCGGGGCTGCCGATGATGGTCCAGACCACGGCGGTGATCAGGGCCACGATCAGGGCGAACCAGAACAGGAAGGCTGCGGCTCGATCGGCCAGGGCCTGGGCCCGGGAGGAGGAGGCCTGGGCGTCGGCGACCATGCGCTGGATGCCTGCCAGGGCGGTGTCCCCACCGGTGGCCTCCACCCGGATACGGACGGTGTTGTCGGTGGCCACGGTGCCGGCCACCACGGTCTCACCGGTATCCCGGTAGACGGGTCGGGATTCGCCGGTGATCATGGCCTCATCGAATTCGGCCGCTCCGTCGATGATGGTCCCGTCGGCCGGGACGCGGGCACCGGCTCGGACCAGCACGACATCGTCGACGGCCAGCTCTGAGATCGCTACGGTGCGGGTGGTCCCGTCGACGACCTTCTCGGCCTCATCGGGCAGGAGCGCTGCCAGCGCGTCAAGCGCGGAGGAGGCTGCACCAAGAGCGCGCATCTCCAGCCAGTGGCCTAGCAGCATGATGGTCACCAGCAGGGCCAGTTCCCACCAGAAATCTAGGTGGAACCCGCCCAGCCCCAGGGTGGTGACCCAGGAGGCGATAAATGCCACGGTGATCGCCATGGCGATCAGGAGCATCATGCCCGGTTGGCGGGATTTCAGCTCGGTCATTGCGCCCTTGAGGAAGGGGGTGCCGCCGTAGAGGAAGATGATCGTGCCCAGAACCGGAGGAATCCAGTAGGCTCCCGGAATCTCCGGAATATTATATCCCAGCAGGTCGGCGAACATCGGGCTGAAGAACACCACCGGAACCGACAGGATCAGCGACCACCAGAAGCGGTCCCGGAACATCGCGGCGCTGTGGCCGGCGTGTTCACCGTGACTGTGGACCTGGTGTTCTTCATCGACAGCGGAATGCGGATGATCGTGTGGCATGGCATGGCCGTGGGTGGCGGCATCCGCATGGTGCTCGTGACCGGCATGATTCGGGTGGTGGGTGTGGTCTGTTTCCGGAGCGGGGTGATCACCGTGGTGGTGGGGAGTGCTCATGAGGTTCCTTTCGCTCAACCCGGTCGGGGTCGAGATGATGGGCGAATCGATCAGGACAAGACGGTGTAGCCGGTCTCCTCAATCGCCCGGTGGACGGTTTCCAGGGGCACGGAACCCGTGACCGTGACGATGGAGACCCCACCGGCGATGAGGTCGACCTGGACGTCGTCGACCTGGGGCAGAGCGCTCACCGCCTCGGTGACGTTGCCGGCGCAGTGTCCGCAGGTCATGCCTGTGACCTGGTAGGTGGTGGGACCTTCAGGTGTTGCGTCGGTTGCCGCGGCCACGGCCGGGGCGGAGACGGTCGCGGACGGCGTAGAGGGCGCGCAGCATCCACAACCGTCGGAGGCCAGCGGCAGCAAGGGGGAAGTCGGGGTGGTCATCGGATCGCTCCTGTGGGATCGGGGGATCAGGCGGGGTTTCCCTTCCCATCGTATACCCCTATGGGGTATTGTCAAGGGGTTGATACGGATCGCTGCCGAGGTCATCAGAATTATTGTCCCCGGGAGTGGGGTCACTGAGCATCAGGGACACGTTTTCCTGGTGCAGGGGAAGACGGATGGTGAAGACCGATCCGGCACCTGGGCCAGGAGAGGTGGCGGTGAGAGTGCCGCCGTGGGCCTCGATCAATGCCTTGGAGATGGTCAGACCGATACCGGCCCCGCCGTTGTCCCGGCTGCGGGCGGCATCCCCCCGGTAGAAGCGTTCGAAGATGTGTCCGAGCTGGCCAGGTGGGATGCCCTCGCCGTCATCGGCGACGTGGATGAGCGCGGTGGACGCCCCCTGTCGGTGGACGCTGATCCGGACCTGCCCGCCGGCCGGGGTGTGCCGTAGTGCGTTCGACAGGAGATTGCTCATCACCTGGCCGAAGCGTTGCCGGTCCACGAGCACCCAGGCGGTGTCCGTAATGGTCTCGACCTGTAAATCGACGCCTTTGTCAGCATAAGCTTCCCCCGCGGCAGCAGCGGCGGTATGGAGCAGATCCCCGAGCCCTTCCTCCGCCAGGTCCAAATCGATCCGGTGTTCCTGGGCCCGGGAGACATCGTCGATGTCTTCTATCAACCGGGTCAGGCGGGTGAGTTGGTCAGCCATGATCGTGTGGGTGGCATTATTCCAGTCCACGACCCCGTCCTGGAGACCATCGAGGTAGACCGTGAGCACCGATAAGGGGGTGCCCATTTCGTGGGCCAGATCAGAGAGCATCTGGCGGCGGACCTGTTCGGTGTGTTCCAGCCGGTCGGCCATGGTGTTGAAGGCATGAGCCAGGGTGGTGACCTCGGGGCCTGCTTCTCCGGCGGGCACGCGGATACAGTAGTTGCCGGCCGTCAGGCTGGTAGCGGCGCGGGTGAGATCCTGCAGGGGGGTGCGCAGGCGACGCGATAACCACAGGCTGGCCAGCAGGGCGCTGATCAAGGCGGTGGGCAGGGCGACGGCCAGGGTGATCAGGTTGGCGTCCCGGTAGGCCTGCTCGGCATGGAACAGCTCCAGCGAGGGGTCCTCCCGGCCGGTCATCAACATATGATCATGGAACAGGGTCGGGCCCACCATCGTGGCCACGGCCGCGGCCACCAGCAGGCTAATCACCACGACCAACACCTGGGCGGCCAGGAAGCGGAAGGTCAGGCCGGGTCCGTGATTCATGGCTGCCCCACCCGGTAGCCCACGCCACGCACGGTGTCGATAAACCCCCGGCCCCGGGTGTCGGTGCCGAGCTTGCGACGCAAGTTGCCGATGTGGACATCGACGATGCGTTCATCACCGACCCAGGTGGTGTCCCAGACCTCGGTGACCAGGTCGTGGCGGGTCAGTACCTGGCCGGGGCGCAGGGCCAGGGCAACCAGCAGCTCGAACTCCGTGCGGGTGAGCTCCACGGTCGTCTCCCCCACCCGCACCTGATGGGCGACGGGGTCAAGGATGAGGTCACCAACGATCAAGGGGGTGGTCACCTGCGGTGGGGTGGTGCTGGTGCGCGGGCGGCGCAGCACCGCATGCACCCGGGTCACCAGTTCCCGGATGCTAAAAGGTTTGGTGATGTAGTCATCCGCCCCCAGGGTCAAACCGCTGATCTTGTCGTCCTCGCTGCCACGCGCGGTGAGCATGAGGATGTAGCAGTCCGAGAAGGTGCGGATCCGTCGGCACACCTCCAGGCCGTCGAGTTCGGGCAGCCCCAGATCCAGCACCACAACATCGGGGGAAAAGCGACGGGCCTCGTCCACGGCCTGGGTGCCGGTGTGCGCCTGGCGGGTATCGAAGCCGGCCCGGATGAGGTAGGAGGCCACCATCTGAGCCAGGGGTTGTTCATCATCGACGACCAGCACCCGCCCCGGGGGCGTGGCGGTGGTCGGTGTGCGGTCAGCCATAGACCCCAGTATCGCTCCGGCCAGGGGAGAATACCACCCTCGCTCAGTGCCCGGCGGGGAAACCTTCATCAAATCTTCAAACATCACCCTTCGACCGCCGTCACCCCTGTGCCCCACCCCGGGCCGGCGGCATCGCCTCCCCTGGTCAGTTCAGCAGGCGCCACCAGGGATTTCACTGCCTGCACCGCATACCCGGGGCGGGTAGAAGGACATCGCCCACGGCTGTGGGGTGGTGTCCCGGTGGTGACCCAGCCCACCGGAGTCACCCCCTTTTCGCCCTGTTATAAGGCTGTGAGCAGGGTTTTTGATTTCTGGGCCGTCAGGCACCCGTGCTAGAAAAGGTATGGCATCGACCTTGAGGCAGTGTCTTCTCACGGTCTTACCACGATCCAAGGAGATTGACGTGAAACGAGCAGCGATCGCAGCCGCCGCCCTTGCCCTCGCCCTCACGGGGTGTTCGGCCGCCGACCCGGAACCCACCGCCGACGGGACGGTGTCCCAGGATACATTCCTGACTACCCATGGCCTGGCCGCCATGGACGCGGTGGAGATCATTGATCACCTCGACCGGCAGAAGGTCACTGAGCGTCCCACGGATCTGATCGCCTCCGTGCGTGCCGATGAACTGCTGCTGTCGAGCGATGACCAGGAAGTCGTGGTCGATCTTCCCGACAATCAGACGTATGTCTCGGTTGCTCCGTATATCACCTCCACCCACGACTGCTTCTACCACAGCCTCACGACCTGCCTGGGGGAACTCGACAATGAGGATATCCAGGTCACGATCACCGATGAAGCGACCGGCGAGGTCCTGATCGATGAGCAAACCACCACCTTCGACAACGGGTTTGTCGGCTTCTGGCTTCCCGATGATGCCACCGGCACCATCGAGATCACCCATCAGGGGCGCACCGGTGTCACCGAGTTCTCCACCACCGAGGACGGGGCCACCTGTGTCACGGACCTGCGCCTGACCTGATGCCTCAGCAGTGGGTTTCCCCTGATCCTTCCCCTGTGTCACTCAGACTTGCACCAAGGACGGTTTAACCATGACAAGTAGTTTTTCCCGGCGACAGTTTCTGCTCGGCGGGCTCGTACTCGCCGGCACCGGGGCCGTGGCCGCCTGCACCAGCGACCCTGGACCCGCTGCCTCGGCACCAGGTCCCTCCCTTCGCCCCACTCCCACCCCCCACTGCGCTCGGTGAGCCGACGGTGCGCCGGACACTGACCGCCCGGCCCCTCTCCCTGGATATCGGCGGCATCGAAGCCAAGACATGGGGATACGTCTCTGACACCGGGGATGCGGCCATTGAGGCCACCGCCGGCGACGTCCTCCAGGTCGATATCACCAATGAACTGCCTGAGAGCACCTCCATCCACTGGCATGGCATCGCACTCCACAACGCAGCCGACGGTGTGCCCGGCATGACCCAGGACCCCATTGAACCTGGCGAGTCTTTCTCCTATGTTTTTGAAGTCCCCCACGGTGGCACCTACTTCTACCATTCCCACACCGGCCTGCAGCTTGATCGCGGCCTCCACGCCCCACTGATCATCCGTGACCCGCAAGACGCTGAGGACCAGGACGTCGAGTGGACCATCGTGCTCGACGACTGGGTCGATGGCATTCAGGGCACTCCCGACGATGAGCTCGACAAGCTCACCGGAATGGGTTCGGGCGACCATAACGGGAGGATGGGAATGGGAGGTCACGGCCAGATGATGCACGGCACCCCGGACCGGGTACTGGGCGGGGATGTCGGCGATGTGATGTATCCGCACTACCTCATCAACGGACGTATCCCCCGTGCTCACCGGACCTTCGAGGCTCGCCCGGGCGACAAGGCCCGCCTGCGGTTTATCAACTCCGGCGGTGACACCATCTTCAAGGTGGCCCTCGGTGGTCACCGCATGACCGTCACCCACACCGACGGCTTCCCTGTCCAGCCCTGGGAGACCGAATCGATCTACCTGTCGATGGGCGAGCGTGTCGACGTCGAGGTCATCCTCGGCGACGGCATCTTCCCGCTCACGGCTTTGGCGGTGGGTAAGGACGACCGCGCCTTCGCCGTCATCCGCACCGCCGGCGGCCAGGCCCCCCGCCCCGATGTCGACTTCCCCGAGTTGTCGTCCACCGGACTGCTTCTGTCCTCCCTGAAGCCAGCAGACCGTGCACTCCTGCCCGAGGGCACACCAGACCGAGAAGTCAGCATCGACCTGGGCGGGCAGATGATGCCGTATGAATGGAGCATTCTCACCGACGGCCAATCCTCCTCCGCGACCGTGCAGGAGGGCCAGCGCCTGCGGATGGTCATGCGCAACAGGACCATGATGCCCCATCCCATGCACATCCACGGCCACACGTGGGCGCTGCCCGGCAGCGGCGGGCTACGCAAGGACACCGTCCTTCTCCGCCACGGTGAAACCATGATCGCCGACCTGATCGCTGACAACCCCGGTGAGTGGGCATTTCACTGCCATAACGCCTATCACATGGAAACCGGGATGGTCAGCTCGCTTCGCTACGAGTAACCCCCACAGCAGGGTTGAGTGCCGAGGTGGGCAGAGTCGCTGCAGACCACCCACCGGGCAGCACGATGACCTTCCTCGGTGTTGTGGTCTTCCGGGACAACCAGAACACCGTCTTCTTCCCCACCGCCCCGGAATAAGGAGATCTAATCCATGCCGAGCACACCCCGCAGAGCCGCCATCGCGGTTGCCGCGGTGCTCACCGCCGTGACCCTGGTGGCCTGTTCGGTGCTGTTGCAAAGTTGGGGCAGTAGGAAGAGCGACGTGAAATAATCACAGCCATGGGTATCTTCTCCGGTCGTCATTTCCCCGTGACATCATTCTGTAGGCAGTGCGCAGGTCACTGCCGCTACGGGGTGAGCTGACCTAAGATCTGGAGGAAATGATGACTTCAGCGGGGCGTGCCGGTCGATCACACCACGATTCTCACCGCTGGGTCCAGAAATACGCCCCTGAGCTGGACAAGCAAACACGGTGGTACCGGCAAGGTACCTGACTGGCAGGCTAAGTTCCTGGCGGGTGGATGAGACCTATATCCGGGTCGGCGGCAGGTGGTGCTACCTCTGATCTGGCGATCACCGCCGGTGGCCAGACCCTGGACTTTTACCTCTCTCCGAAGCGGAACGTGGCCGCAGCGAAGCGTTTCCTGGCCAAGGCCCTCAGATCCAATGCGTCAGCCGGGTATCCCAGAGTGATCAACACCGATAAAGCACCGTCTCTAGCCAGGGCAATCGCCGAGTTGAAGTCAGAGGGAATCTGCCTGCCAACAGTGGAACACCGGCAGGTGAAATACCTCAACAACATCCTGGAAGGCGACCATGGTCGGCTGAAGCGGATCCTCGGGCCGAAAGGCGCGTTTAAGAACTTAGACATCTGCATATCGGACGTTGAAAGGGATGGAGGCGATGCACTCATTGCGGAAAGGGCAAGGCACGATGTTTGACCTTACGGGCAACCGAACCCGGACGCGGTGATCGTCAACCGGGTCTTCCAGAATATCTAAGCAGGCTGGGCCATAATGCTGGCCAGGCGACGAAGAAAGGAGTGTTCGCGGTTCTCCACCCAACTTTGCAACAGCACCGGCCGTGATCACCCTGATGGGTGACCCACCTTTTTCGTCCCAGATGTTGGGATATGAGCAGTCCACCAAACAGGGGTCAGGCCCGAAAGCCCGAGGCCGTGCGACTCCAACCTAGATATAATTGTTGAAACAGCGGAAGCATCACATCTAAAAGCAGTAGGAAGGCTAAGAATGACCAAACAAGAATACTACGACTACAGCAAAACCTATGAATATAACGAAGAAAGTCCTTATACGGGTGCACTTGCAGACGGGGTTGAAGAAGCAACAATTCTCAGTGGAGAAGTGACATGGAGCGCAGACATCACCTGGAACGAATCGCTCGAACAATACGAAATATTCAAAACTTGGAATGATCATGATGGCCACTTCAGCAATATGGGTGAGGGCCCGCTGGAAGATGATTTCCTAAACGATGTGTACTCTTTTCTGCAAAGTAAGGGAATTGACTCCGCAGAAGTCACTTATTGATCTGGAAAACAGGTACCAGAGGCCTAGTACCGGGGCTGCTGTGAACTTTTTCCCCGGTACTAGGCCACTGGACCTACTAAAAAAATACCAAACCTACTGGCTTTCACCACGAAAGAGGTAATACATGTTTAAAATTCGCATAATTTTCCCCGACGGAACTGATGAAGAGCAAGATGAGCATTTCGATACGGAAAGGGAAGCTGAAGAACACGGTGCTTACCTAGCGTCTTGTTATCGACAAGGTAATGAAATACTCCATATGTCAAACCCAGGGGATTACCCACTGGAAGATGAAGATGCAGACTACGAAGTGATCGAAGTAGATGAGTAAAAAGATATTTTGTTAAAACTCCGAAATTTCTTTACTAAGCAACTACCTGGAATGCCTCTAAAAATGTGAAAGCTCAATGACGCATATACTATTCTATAATCAATAAATTATAGAAATAAATATTGATAACTATAAATTCTGTGTTGCGTCATGGAAATCTTCTACGATTCTCATTGCCCTATCGGTGTGGGCAGTTTCTTTTATCGTGACCATGGAAACCACATACACTGCATTCGCCTGCATTAGAGGAAACCTGGCAAGAACGCTTATCGTGCCCAGCCTCTCCACACCATGAGCATGTACGTGTCCGAGTATTCTCCATAGCAGTTCCTTCGCATTCTCAAAAAATAATTCCAAAACAATCTTAGCAATACCGCGAACTATCTTTGTGCTGGACACAGGGTAAAAACAAATTTTACCCTGTTCTTAGTAGTTTCCACTTTTTAGCCCACGTAGACTCTGCATACCGATTTTCAAGTGCTGTTATAAGGAGCTGCGCCCGTATGGTGATTTGAGACAGGGTCTAGGAGAATTAGTGCCATGTCGAATCGCCGCATCTTCACCGAAGAGTTCAAAGCAGGAGCTGTGCAACTCGTCGTGTCATCTGGGCGCTCCATCAAAGAAGTAGCCACCGAGCTAGGCATCAAAGAAGGAACACTGGGTACGTGGGTGAGAGCCTGGAATACTGAGCACCCTGATGCTGGTGTGGATGAACCAGGCCCAGTTGAATGGGCGAAATACAAGGCCCTGCAGGCTGAGAATGCTGCGTTGAAACGAGAAAATGAGTTCTTGGGAAAAGCCAGCTTCTTCTTTGCCGCGAAGCGCCTGTAGAGGATTTCTATGCGTTCATCGAGCAGGAGAAGGCCGTCTTTCCTATTACATGGATGTGCAGAAAATTGGGCGTGTCTAGGGCATCGTACTACCGCTGGGCCAAGCCTGCGGGTCTGACTCCGACAGCCATAAGGCATTCAGAACTCAGGGCTGAGGTCGCCCAGGAGTTTGAAAACAGCAACCAGATGGCTGGCAGGGATCAGCTGACCACGCTGCTCAACCAACGTGGCGGCAACGTTTCTACTGGAACCGTGGGGGCAATTATGAACGAATTAGGACTGCGTGCCAGGCGGATGCGTACCTGGAAGAACACCACGGTCAACGACCCAGCAGCCCGGACCGAGCACATCAAAAATCATATGATCGACAGCCACGGGAAACGAGACTTTATCGCTACCGTGCCTGGGACCAGGCTCGTTGGTGACATCATGGGTGTGAATGTACCAAAAAGTCACGATATTTGGGGAACATTTGTTCTAAAATTTGTGCCATTAAAGTGGAGTGAAGCTAGGGTTAATATCACCCCCTACGCCGAAGAGAACCATGATCAATAACCGCTTAGAAGCTGCAGTCGCAGACATGGCCGCCCGCGTCCATGAGCAGATCAGCGCTGCTACGGCCTCTCATGTCCTGGCAGCATACAAGCCCATTCTTAGCACTGAGAAGATCAGGGAAATGACGTGTGTGAAAATCCCAAACCCAACCGAACATGCCACGCAGAACATTCGGATGTATCGAATCAGGCAGTAAGGACTCACCAGGACTTCATGACTGACCTGGCTAAGCCTCGATCCACCGATGTGGCCTCGGTAACGAGCTGATTCTGACTCCGGTTGGGTCGGGAGTTTTCGGGTAGGGGCGCTCCCCAGATCACGTTTTGTTGGATCAACGAGATCGACTACCCCTGTGTTCTCTCCCTGCACCCTCTTCGCATTTTAACGGAAATTCGAGACCACCGTCCATGCTGCACTGCCTGCTGTCAAAAGTTAGCAATCATGAATTTCTATTTGTAGCAGCACCATATATTAACCTTCATAGCTGTACAGTGGCCCATTACTAGACACGACCTGGAGGCCATGCGTCGTTACTGCGAGGCTGATGACATCAGAGATCCTGCGCACACTCGGGATGCGTAAGTCCGTGGAGCCACCGGTTGCTTTAGGCGACTGCGCCTTGAATGTTATGAGTTCTTCCGTACTTAAGCCGTGAGGATCAGGCACTCCAAGGTGCGCGGCTTTGAGTAAACGTGCTCTTTTTTGCATGGCTAGCCAAATCGTTGTGGCGATCCATCCATCTAGCTGCGTAAGTTCTTTACTATTGTTAACCAGGGGAAAGTAGGACATAACCCCATCGAACTTCATTTTTGGAATTGAGCCATTTCGAAATCTACGCAAATCCGATTCGGTGAGGGAGCCGTAGAGATAACGCCTGAGTTGAAAAATTAGCGTGACGTAATCTTTGTCTACATTCGTTTCTGTGAGACGGTCTGAGCACTGGGAACCCTTGGAAGGCTCGAGTAGAAGGTTAGTGTAGACGAGTTCTGTGATCCGCTTTTTTATTTTGGTGCTGTTGCAACTTGGGGCGGGAGCCAAGAAGGCTCCGTTTTTATTGTGTGATCAACGCTATGTGCCTGTGTTGTCAGGCCGTCTCGAATACCCGGCTAACAATCACTGCATCCGGATTCGGGTGACCATAGGCAAACATCGTGCCCTGCCCCTTCCGCAATGAGTGCATCGCCTCCATCCCTTTCAACGTCCGGTAGGCAGACGTTCGGTTTTTGAATGCGCCTTTCGGCCCCAGGATCCGCTTTAACCGACCATGGTCGCCTTCAATGACGTTGTTGAGGTATTTCACCCGACGATGCTCGACCGTCGATGGACAGACGCCTTCCGCCTTCAGCTCAGAGATTGCCCTGGCGAGTGAGGGGGCCTTGTCGGTGCTGATCACCCGCGGATAGCCTGCCGATTTATTCGACCGCAGCGTCTTCGCCAGGAAACGCTTCGCCGCCGCGACGTTTCTCTTCGGGGAGAGGTAGAAGTCCAGGGTCTGGCCACCGGCGGTGATTGCCCGATAGAGGTAGCACCACTTTCCCCCGACCCGGATATAGGTCTCATCCACCCGCCAGGACCTGGCCTGCCAGTCAGGAACTTGCCGATACCACCGGGTCTTCTTATCCAGCTCAGGAGCATATTTCTGGACCCAGCGGTAGATCGTGGTGTGATCGACCGGCACTCCCCGCTCGGTCATCATCTCTTCGAGGTCGCGATAGCTCACGCCGTAGCGGCAGTACCACCGCACCGCCCACAGGATGATTTCACGAGGGAACTGCCGACCGGAGAAGATGCCCATGGACCTGATTATTCCACGCCGGTCTTCCTACTGCCCCAACTTTGCAACAGCACCGTCGCAGATGACGTGCACGTCCAGGCCCTCGGGGACGGTTTTGTCGATCTTGACCAGGAATTTTCTGAACTCCACCGAGCGGTGCTTGCGGTGGACCTGGGAGATCACCGTCCCATCGGCAACGTTGAGTGCGGCGAACAGACTCGTGGTGCCGTGGCGGACATAGTCGTGTGCGCGGCGCTCGGGTGTTCCCGGCATCATCGGAAAGGCCGGCTGGGACCGCTGTAGGGCTTGTACCTGGCTTTTCTCATCGACACACAGCACGACCGCTGACTCCGGTGGGTTCAGATACAACCCGACGATGTCATAAATTTTCTCGGTGAAAAAGGGATCGTTGGAAAGCTTGAACCCCTCCTCCAGGTGGGGCTTGAGTCCGAAAGCCTTCCAGATCCGACCGACCGTGGACTTCGACAGGCCGGATTTCTCGGCCATGCTCGCCCGCGACCAATGGGTCGCATTCGCAGGGGTTGATTCCAGGGTGTCGATGATGACCTGCTCGACCCGGTCGATACCGATCGTCGCGGGCCGACCCGGCCGGGGCTCGTCGACCAGTCCGTCGAGGCGCTTGTCGATGAAGCGGGCCCGCCATTTACCCACCGTCGGCAATGAGATCCCCAACCGACGGGCGACCTCCGAGTTCGATGCCCCGGTTGCGCATTCCAGTACGATCCGGGAGCGGAGCGCGAGGTCCTGGGTGGTTTTGCGTCGCCGGACCCAGCGTTGCAGTTGGTCGCGTTCATCATCGGTCAAGGTCAGTGGGGCTAACGCCGGTCCTCGGTGTGCCATACCCAATTTTACAATGATCCAGCAGCGAATTAACGGCGCAGGACACTAGGCGAGCTTCCCCCAGGGAACCAAACTCCCGGCGATCGTCTGACAGGCCGGAAGGAGTGTCCGGAAGTCGATGTTGATTCCAGTCCCGTCTGATATGACCCATACGGTGCCGCTGACGGGACAATCCATGAGTGAGTTCCTCTGGATAGCCCGGGGGTTGAGTGGGGGTAAGCGGTTCTCCGACAGATCGGACGGACTGTTCTCGCCACGGGCCCCACTGGTGACTCGCGGGGAGAAGCATCAGTGCGTGGGCTTTTCTTCGTGGTCGATGCCGGCGTGTTCCTGGCCTTTCTGGAAGTTGAGCAGGCGAAGCGCGTTCGCGACGACGATGAGGGTGGATCCCTCATGGATGAGCACGACGGCGCCGATATTAAGCCCAAGGAAGGTCGCGATGATGAGGAAAACGACGATGGCGAGGCTGGCGATGAGGTTCTGTCGGATGATCCGGCTGGCGGCCCGGCTCAGCCGGACAGCGAACGGGATGCGTCCGAGGTCGTCGCTCATCAGCGCGATGTCGCAGGTCTCTAACGCGACCGTCGACCCGGCAGCACCCATCGCAATGCCGACGTCAGCGCGGGCCATCGCGGGGGCGTCGTTGACGCCGTCGCCGATCATCGCGATCGGGCGGTATGTCTTGGCCAGGCTCGTGATGTGAGTGACCTTGTCCTCGGGGAGGAGCTCTCCGATCGCCGTGTCGACGCCGACTTCCTGACCTACCGCGTCGGCGACCCGCTGATTGTCGCCGGAGATCATGACCAGATGGCCGACCCCTGTGTCCCGGAGCGCGTTGAGCACCTGGGCGGATTCGGCGCGGGAGGCGTCCATCACTCCCACGACCCCCAGGAAGCGGTCACCACGACGCACGATCATCAACGTCTGCCCAGAGTCGCGGGCTTCGGCGTAGGCCTTGGCCAGCGAGGAGGGCAGTTCAAGCTGCTGTTCGTCGAACATGCGCAGGTTGCCGATTTCGACCCGCTCTCCGTCGATCGTCGTGGTGATGCCGCGGCCGGTGAGTGCCGAGAGGTCGGTGGCCACCAGCCGCCCGGTCTCGGGGACGCGGGGTGCAAGGTCGCGGACGATCGCGGCGGCGAGGGGGTGGTCGCTGAGAGATTCGACCGACACGAGTGTCGGGATCAGTTCCGATTCGGACGTGTCATCGGCGGGAACGAGCGAGGTCACTCGTGGTGCGCCCCACGTGAGGGTGCCGGTCTTGTCGAACGCTATCGCCTCTACTCGTCCGAGTGTCTCGAGCGGGGCACCGCCCTTGACGAGCACGCCGGCACGGGCGGCGCGGGCCACGCCCGCCAGGACTGCGGCTGGGGTGGCGATCGCGAGAGCGCATGGGCTCGCGGCGACGAGCACAGTCATGGCGAGGTAGAAGGCGTCGCGGAACGGCTGCGCGAACGCGAACATCGACACCAGCAGGGTGGCGATGACCCCGAGGATCACGGCGGGCACGTACCAGCGCTGGAACCGGTCGATGAACTGCTGTGTCGGGGACGCAGCCTGGTCGGCGGTGCGAACAAGCTCAACGACCTTGCTCAGTGTCGAGTCAGCGGCGGTCGCGGTGACCTCGATCTCGAGTAGGCCAGACCCGTTCACGGTGCCGGCAAACACTCGATTGGTGGCGGGGAGGGTGCCGACCGTGTGCATCGTCCGTGTGGGGTCGGACACCGGTTCCTTCTCCACGGGGATCGACTCGCCCGTGACTGCCGATTGATCAACGGCGGACATTCCGGAGATCACGAACCCGTCCGAGGGGATGCGGGAGTTCGGACGGATGACAACGATGTCTCCGACCACGAGCTCCTCCACCGGTACTTCCACGGGTTCGGTTTCGCCGCGGCGCACCAGGGCGCTGCGGGGGGCGAGCTCGGCGAGGGCCTCGATGGACTTGCTGGCACGGCTAAGGGCGTACTCTTCGAGCGCGTGGCCGAGGCTGAACAGAAACAGCAGCACCGCACCCTCCGCCCACCGGCCGATGAGAGCGGCGCCGACCGCGGCGACGAGCATGAGGAAGTCGACCTCGAACTTCCCTCGCAGCGTGGAGGAGATAGCGGTGCGGATGGTGAAGAACCCACCGAAGAAGTAGGTGGCGAGGAAGAACGCCAACGGCCATCCGACCATCGGCAGCCCCAACGCGAACTCCGCGATCATCCCACCGGTGTAAGTGACGCCGGCGGCGATCGCGAACCACAGCTCCCAGCGTGCGGAACCGTGGGCATGATCTTGGGTATGAGTGGCCGCCGATGTCGGTGGCAGGGTTGTGGGGGATCCGTTCGGGGCAGTACGGTGGCCGGGGTCATGGTCGTGTTGGTGCTCGCTCATGCCTGTAGCCTAACGGGGAAAACCTCTTATTGAAAGCTTATTAAAAATCCTTGAGGGTATCCCATTCCGCACCCTCCGTATAGACATCGAGCGGGCCGCACCGTGTGGTGCGCAAGGCTGCGGTTAGAACCGCTCGTGCCGGCGGTTGGTGAATTTCCGGGAGTGGTTCGGCTGGCTGTCGCCGTAACGGTCGTGCAACATGCGTGCACGGGCACCAGAGGATGCGGAAGTAGTGGCTTGGGCATGGGCGAGACCCTGGGTGTCATTTTCCGGGTGAGTGGTGTGGAGGGCGCCCACCGGGTCGGAATCTGTCTCTTCGTCCTGGGAGTCCCCGGTCTGCTGCGAGGATGCGGATCCGTCGGCCAGCTCGGCCTCCTCGCGGCGCACACGGCGGCGTTCCTTCAGCTCCGCCCAGATAAAATACCCCAGGCCGAGCGGGGCCATGATGCCGAAGGCGATCCACTGGAAGGCGTAGGACAGGTGCGAACCGCGGTCGAGCATGGGCACCGGGATGGCGTTGATCTCCCCGGCCTGCCCCTCGGCCAGCTGCACATAGTCCTCCGCCAGGTCCCTGCCGGTCACCTCGGCAATCTGCGCGGTGTTGATGCCGTAGACCTGGCGGTAGCCCTGGTCCTCGATCGGGGGGGACATCGGTGTCTGCTCGGTGAATCGGGCGTGGCCGACGATGGACTGCTCACCGGCTGGCGCAGTATCCATCGGTGGGACACCGCCCTCAAGCGGCGGGTTGAAACCCCGGTTGACCAGGATGATCTCACCGGAGTTCAGCTGGAAGGGAGTCAAGGCATGGAAGGCAGGGGAGGAGTCGACCGGACGGTTGCGCATCAGCACCTCATCCTCGGGCAGGTAGTGGCCCTGAAGGATCACCCGGGCCCATTCCTCCCCGGGCTCGATACTGCCCTGGGCGTCAAAGATCTCCTCGGCGGGGACGGGCTCGACCTCGAAGGCGGCTTCGATCTGCTCGTTGCGCTCGACGATAGTGCTATCCCTGCTCAGCTGCCACGGCGCCAGAAAGGTAAAGGCGACGTAGGAGAAAGCGATGATGGCAAGGACACCGAACACCCAGCCGGGCCGGAGGAATGTCCGCCAGCCCTTCTTCTGCGGGGCCCGACCGTACCTGCGTTCACCTGTGCTGCTCACAGCCATGAAGTCTACTGCCCCGTCCGGTGGAAAGTACATCCTGTCGCCGGGTGCTCATGGGGAAAGCACTACGAGACCCGGGACCTTCCGTACGCATCCTCGTCGGCGGTGACCGTGGTCGCCTCGACGGGCTTCAGGTCAAGATGCTGGGTGCGGGCGGCGCGTAGGCCGTTGGCGATGACGATGACCTCGGCCACCTCGTGGACCAGCACGACAGCAGCCAGTCCCAGCACGCCGGTGATCGCCAGCGGCAACAGGACGATGATGATCGCCAGGGACAGCACAATGTTCTGGTTGATGATCGCCCGGCCCCGGCGGGCGTGGCGCAGAGCCCTGGGGATCAGGCGCAGGTCATCGCCGGTAAACGCCACATCCGCGGACTCGATCGCCGCGTCCGAGCCCTTGGCACCCATGGCGATACCGATATCGGCTCGGGCCAGGGCGGGCGCGTCGTTGATGCCGTCACCGATCATCGCCACCGGGCCGCGGGTCCCCAGTCCGGCCACGGCGGTGGCCTTGTCCTCCGGGCGTAGCTCGGCCCGCACGTCCGTGATGCCGGCCTCGTGGGCCAGGGCGGTGGCGGTGCGGGTGTTGTCGCCGGTGAGCATGGTGACCCCGAAACCCTTATCGGTGAGTGTCCGGATGACTTCGGGGGCCTCGGGGCGGAGTTCATCGCGCACCCCCACCGCACCGACCGGGTGGTCGTCACGGTAAACGATGACCACGGTCATACCCTGGCTCTCCAGGGTTTCGACCTGCCCGACCAAGGGGCCAGGGGACAGCCAGCGGGGACTACCGACCTTAATCTGCGTCCCGTCGATCACCCCAGTGATCCCCTGCCCCGCAGTCTCGTCAACCTGCTGGGCAGTCGGCGCCTGGGGTGCTGCGGCGGTAATAGCGGCGGCCAGCGGGTGGGTGGAGTGATCCTCGAGCGCGGCAGCCCAGCCGAGGACATCTGCCCGACTGATGCCATCGATGGTGAGCACCTCCGCAACAGTGGGCTGATTGCGGGTTAGGGTACCGGTCTTATCCAGGGCCAGGTGGCGGATGCCACCGAGGCGCTCAAAAGCGGCGCCGGACTTGATGACCACCCCGAACTTGCTGGCCGCCCCGATCGCAGAGACGACCGTGACCGGCACCGAGATCGCCAGCGCACACGGCGAGGCCGCGACCAGCACGACCAGGGCACGCTCAATCCACACACCTGGATCCCCGAACAGGGACCCGATCACGGCAACGAAGATGGCCAGAATGAGCACCCCCGGCACCAGGGGGCGGGCCAACCGGTCGGCGATACGCGCGCGTTGGCCCTTCTCACTCTGCGCCTGCTCGACCAGCGCGACCACAGTGGTCAGGGAATTGTCCGTGCCTCCGGCGGTGGCCTCAACTTCGAGAGCCCCGGTGGTGTTGATTGAGCCAGCCAGCACCGCGTCACCGGGGCCGACCTCCACAGGGATGGATTCCCCGGTGATCGCCGAAACATCCAGGCTGCTGTGCCCGGAGCGGATGATCCCGTCGGTGGCCAGGCGTTCCCCGGCAGCCAGGCGCAACACGTCCCCGGGGACCAGCTCCTCGACCGCCACACTGCGGGTCACCCCGTGGGAGATGATGGTCGCGGTGGAGGGGATGAGGGCCAGCAGGGCACGCAGGCCCGAGCGGGCCTTGTCCATCGCCTTATCTTCCAGCGCCTCTGCGATGGAGTAGAGGAAGGCTAGGGCGGCGGCCTCCTCGATGAACCCGAGCAGGACGGCACCGGTGGCGCTGATCGTCATCAGCAACCCGATACCCAGTTTTCCCCGGGTAAACAACCCCTTCAGCGCCCCAGGAACGAACTGGGAGGCACCCAACAACAGGGAGGCCCAGAATAAGACGAGGGCGATCATCCCGGCATTGGGGACGAACCACTCAAGGATCAGACCAACCAGCAACGATACACCGGAGGCCACAGGAAGGAGGATAGCCCGATCACGCCACCAGGGCGTGTGCTCCTCTTCTCTGGCCATCGGTGCAGATGGTTCACAACCACAGGCAGACGTCATGACTGCTGGCCTCCTTCTGTATCGCAACAGCCGGCGACCGGACAGGCAGGGTCTAGGCAGGGGGCATCCTCATCAACGGCGAGGGTGATCTCTACCAGGGCATTGAGCGCGCGGGCCAGGTGTGCGTCGACGATCTCATAGCGGGTACGCCGCCCCTCCGGCTCGGCGACTACAATCCCGCAGTCGCGTAGACAGGCCAGGTGGTTGGAGACATTCGTCCGGGTCAACCCCAGCGTTTCGGCCAGTTGGGCCGGATACCCGGGGGATTCGAGTAGGGACAACAGGATCCGGGACCGGGTGGGATCGGCCATGGCACGGCCCAGGCGATTCATCACATCAAGACGAGAAGCAATAGTCAGCATGCACTGACTATACAGTGGGGACTGATTAGTCTGCAATTGTCCCTAGGGTGGTCGCCCCTGGATGTCCGACGAACGTCAGGTGGGAGGTGGGGTCCTGAAACCGCGTCAGCCTGGAGGGAGATTGACCCGCGGCATGGCACACCGGCGCTCAGGATGTAGCGGGAGTCTTCTGCTCCCTAACGCCTGTCACGGCTCCGGACAGCCAGCACGATGGCCCCGGCGATGACGCCGAAGAGGGCCAACCCCGCGAGGGTCAGGACTATCGGATTACTGACTATGGAGGTGTCCCCCTCGGCGGTGTTCTCGACAGCTGTGGTCTCCTCCACAGGCTTGGCGTCGGCGCCCGTGGGGGTGGCGGTCGTTTGGGCGTCACCGGCGACGGTGAAAGTGGTCGCGCTGCGGGTGGCGTGGCCGTCGGAGGAGAGGATCTGGAAGCCGACGGTGTAGTCACCTGGCCCGCCGCTGACATCCGCAGGTAGATCAAGGGTCACCAGTCGGCCGTCGATGGTCGGCTCACCACTGAACAGGAGATCACCGGAGTCCTGGTCGGTGATGGCTACGGTGCTGAAACCCTCCTGGGGAAGCCCGGAGAACTTCAGCTCGATGCTGCGGGGAAATTCTTCGACCACTTCACCGTCCGCGGGATTGCCGCCGATCACGGAGTCATGCGCGAGGGCAACCGGGGTGGCTACGACGGTCAGGGCCCCGACCGCCACAACAGTAGCCAGCACACGACGAGGGAGCATGGGGGAGATGATCACGAAAGTCCTCCTGGACTGGGCCGGTTCTTCAACCGGATGTGAGCGACTAAGGCACCTGCCTGCGGGAGGTGCCAAGACACTGGTCGGAACGGGCGGGAGGAAAGTTCCCGGCCACGCCGCCTTCACCGGGTGTTGTTCTTCCCAGGTCGGTGCACCCCTGCAGGGTGCGAACCGGGGAAGAGACCGGTCCCTGGGTAATGTACAAGAACACCCGCAGGCCCCATTAGGGTGAACCTCACGCCCGCTTCCGAGCACACCATGAGAGCGGAGGCGGCATGGACGGCGAAATGGACACAGATGACCCACCCGGTAAATGACACCCCCACTGCCACGGATACGACCACAGGGACGACCCCCACCATCGGGAGCCGGCCTCAGGAGCGGGTGCGCCCCACGTGGCCGTTGTACCTGCTCTTTTTCGCCGTCGCCGGTGCCATCGGCGGGACGGTTGCCTACAGCTTCCTCGGTGAATCCCTCGCGGCCCTGGGGATCCCCAACCCGGGCATCGCGACCACCTTCGGGTTGCCGTTTTTCCGTGCGGTCGGTTGGATGCTCGCTGCCCTGTCGGCCGGTTCTTTCCTGTTCGCTGCTTTCCTCATCTCCCCACGGTTGCCCGGCGGTGATCACGACCGCCTGCACCAGGCCTCGTTGAGTGTGGACGGGCACCTGGCCTCGCGTACCGGTGCGGTCGCGGCCATCTGCTTCGGACTGATCGCGTTGTTGATGATCCCGCTGGTGCTCTCAGATGTCTCCGGCACCCCCCTGGCCCAGACACTGGGCCTGGAGACCCTGACGGTGGCCGTCGAGCAGGTGGCCATGGCCCAGGTGTGGCTGATCGTCGCCCTTATTGCCCTGGTCACCGGTTGTACGGGCCTGATGAGCCGGGCGTGGATCACCCAACCACTGTTGCTCCTCGGGTCAATCCTCATGATCATCCCCCTGGGCCTGACAGGACACTCCTCCTCGGGCGGTAACCACGACCACGGCACCAACTCCTACCTGTGGCACCTGGTCTTCTTAGTCCTGTGGGTCGGCGGACTCATGGCCCTGCTCGCCCACGGGCGTCGCCTGGGACCTGACCTGGATATTGCGCTGCGCCGCTACTCGATGATCGCCCTGGTCTCCATCATCGTCATGGCCGTGTCCGGGCTGGTCAACGCCGCCATCCGCATCGAGCTGACGGATCTGTTGACCACCCGTTACGGGTTAATCATCGTGGCCAAGACCATCGGCGTGATCATCCTCGGTGTCTTCGGGTGGATCCACCGGGCGTGGGTCATTCCGCAGGTGCAGGCCAACCCCGCTGATCGCCGCCTGTTCCGCCAGGTCGCCATCGTCGAGGTGCTTGTCATGGCGGCGGTCACCGGTATCGCCATCACCATGGGGCGCACCCCGCCGCCCCCACCGCGCATCCCGAACCTCTCGCAGATGGTCACCAAGCTCGGCTACGAGCTGTCCGAGAAGCCCACCATCCTCAACGTGTGGGGCATGTGGCGCTTTGACCTGCTGTTTGGTGCCCTCGCCCTGCTGCTGGCCGTCGGCTATCTGGCCGCTGTGTGGCGCACCCGCCAGACAGGTCACACCTGGTCAAGCACCCCCACCGCCTGGTGGTTGGCCGGATGTGTGACCCTGCTGGTGACGATGAGTTCCGGGATCGGGCTGAATATGCCCGCGGTCTTCTCGGTGCACATGGTCGGCCACATCATCTTGTCGCTGGTCATCCCCATCTTCCTGGTGATGGGTGCCCCGCTGACCCTGCTGATGACCGCCTTCGCCCCGGGGGCCCCGGGTAGGCCGAATATCCACGACTGGGTGCGCGCCTTCACCCGCAGCCGGTTGGTGGGGGTGATCACCCATCCGGTGGTCAACACCCTGCAGTTCCTGGTGTTCTTCTACGTCATGTACCTGTTCATCCCGCTTTATGAGCTGCTGATCTCCAAGTACGCGGGGCAGCTGATCATGAACACCGTGCTCCTGGTCTCCGGTTGCTTCTACGTCTGGGGGATGCTCGGACCCGACCCGATCCCGCGCCGGCGCCCAGCCACCGTCCGCCTGGGCTGGCTGGTTGCCTCCCTGCCCGTCCACCTGCTCGTCGGGGTCTATCTCCTGCGCCTGGACACGATCCTGGGCGAGGAGTTCTACCGCTCGCTCCTCCTGCCCTGGGACATCGACCTGCTTGCCGACCAGCACGCCGCCGTCACCGCCTGGGCCATCGGTGGGATTCCCCTGCTCCTGGCGATCATCCTGTTGATCCGCCAGTGGCGCGACATCAGGAGACGACCCCACGATCAGGCACCACTAGCAGTGCCAGCAGAATAAGATCGCGACTGATTCAAAGTGGCCGGTGAACTACTCGCGGTAGAGCAACGTGAGACGATTTCCGGCTAGAGCGTGTTTGATAATTGAGGGTAGCGCGGCATGGGATCATAGATCCCGTGTCGCGCTTCCAACTTCTCACCGATGACCAATGGGCCCTGATCTCCGATAAGCTGCCCCATCGCATCGGCAAAAAGGGCCGCCCCTTCTCCGACCCGAGGCTCATGCTCGAAGGCATCATCTACCGGCTGCGCTGCGGCATTCCCTGGCGTGACCTGCCGGAATGCTTCGGATCCTGGCACACCGTCTACCACTGGTACAACCGCATGGCCAAAGACGGCATCTTCGATGAGATCGTGACCACCTTGATCGCAGCAGCCGACCACCAGGGTCTGGTGGACTGGTCGGTCAGCATCGACTCGACGATCAGCCGCGCCCATCAGCACGCTACGAATATCACCCGCCACACAGGGGGCTTTGTCGAATGA

Protein sequences of DBSCAN-SWA_2

>NZ_CP010451|3004795:3063156|3051492_3052059_-|WP_040968034.1|DBSCAN-SWA
MAPAPSCNSTKIKKRITELVYTNLLLEPSKGSQCSDRLTETNVDKDYVTLIFQLRRYLYGSLTESDLRRFRNGSIPKMKFDGVMSYFPLVNNSKELTQLDGWIATTIWLAMQKRARLLKAAHLGVPDPHGLSTEELITFKAQSPKATGGSTDLRIPSVRRISDVISLAVTTHGLQVVSSNGPLYSYEG
>NZ_CP010451|3004795:3063156|3059225_3059591_-|WP_011896442.1|DBSCAN-SWA
MLTIASRLDVMNRLGRAMADPTRSRILLSLLESPGYPAQLAETLGLTRTNVSNHLACLRDCGIVVAEPEGRRTRYEIVDAHLARALNALVEITLAVDEDAPCLDPACPVAGCCDTEGGQQS
>NZ_CP010451|3004795:3063156|3016278_3016920_-|WP_034983244.1|DBSCAN-SWA
MAASASGKSKTSAGANRRRNRPSPRQRLLDSATNLFTTEGIRVIGIDRILREADVAKASLYSLFGSKDALVIAYLENLDQLWREAWRERTVGMKDPEDKIIAFFDQCIEEEPEKDFRGSHFQNAASEYPRPETDSEKGIVAAVLEHREWCHKTLTDLLTEKNGYPGSTQANQLLVFLDGGLAGSRLVHNISPLETARDLARQLLSAPPADYSI
>NZ_CP010451|3004795:3063156|3005979_3006285_-|WP_034983267.1|DBSCAN-SWA
MAWCAAMTDGDLDADISPRKIGLMTTRTVVEIVRLRHMIAQQLERATIMENEYLKEIAALKKELAHYKQKDHQNQMVIDILGKAIGTRPNPGEGLDEEDAT
>NZ_CP010451|3004795:3063156|3057258_3059193_-|WP_040968232.1|DBSCAN-SWA
MAREEEHTPWWRDRAILLPVASGVSLLVGLILEWFVPNAGMIALVLFWASLLLGASQFVPGALKGLFTRGKLGIGLLMTISATGAVLLGFIEEAAALAFLYSIAEALEDKAMDKARSGLRALLALIPSTATIISHGVTRSVAVEELVPGDVLRLAAGERLATDGIIRSGHSSLDVSAITGESIPVEVGPGDAVLAGSINTTGALEVEATAGGTDNSLTTVVALVEQAQSEKGQRARIADRLARPLVPGVLILAIFVAVIGSLFGDPGVWIERALVVLVAASPCALAISVPVTVVSAIGAASKFGVVIKSGAAFERLGGIRHLALDKTGTLTRNQPTVAEVLTIDGISRADVLGWAAALEDHSTHPLAAAITAAAPQAPTAQQVDETAGQGITGVIDGTQIKVGSPRWLSPGPLVGQVETLESQGMTVVIVYRDDHPVGAVGVRDELRPEAPEVIRTLTDKGFGVTMLTGDNTRTATALAHEAGITDVRAELRPEDKATAVAGLGTRGPVAMIGDGINDAPALARADIGIAMGAKGSDAAIESADVAFTGDDLRLIPRALRHARRGRAIINQNIVLSLAIIIVLLPLAITGVLGLAAVVLVHEVAEVIVIANGLRAARTQHLDLKPVEATTVTADEDAYGRSRVS
>NZ_CP010451|3004795:3063156|3043305_3044505_-|WP_040968029.1|DBSCAN-SWA
MNHGPGLTFRFLAAQVLVVVISLLVAAAVATMVGPTLFHDHMLMTGREDPSLELFHAEQAYRDANLITLAVALPTALISALLASLWLSRRLRTPLQDLTRAATSLTAGNYCIRVPAGEAGPEVTTLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLSVLTVYLDGLQDGVVDWNNATHTIMADQLTRLTRLIEDIDDVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDLQVETITDTAWVLVDRQRFGQVMSNLLSNALRHTPAGGQVRISVHRQGASTALIHVADDGEGIPPGQLGHIFERFYRGDAARSRDNGGAGIGLTISKALIEAHGGTLTATSPGPGAGSVFTIRLPLHQENVSLMLSDPTPGDNNSDDLGSDPYQPLDNTP
>NZ_CP010451|3004795:3063156|3013874_3014027_-|WP_040968016.1|DBSCAN-SWA
MYSLLWHYLPGPWFVKLLIVLALIVLVFFLLMDVVFPWVATLMPYNDVAF
>NZ_CP010451|3004795:3063156|3037073_3037409_-|WP_003859505.1|DBSCAN-SWA
MHKISIEALARKQLKEAVAAPSARAADTVFGGHEKILRQTVVGIRQGAELGERDNHDESTIYVLQGRVQLRTGDETWIGRSGDLLIVPRSRHSLEAIEDSAVLITIAKLTQ
>NZ_CP010451|3004795:3063156|3019885_3020074_-|WP_003858997.1|DBSCAN-SWA
MGSGAFIFGFCTTLLDMDFNAIINPIIEFFSTDLGAVIAQISRTLFDLLFPSNTDAAVVNAG
>NZ_CP010451|3004795:3063156|3042914_3043247_-|WP_006284595.1|DBSCAN-SWA
MTTPTSPLLPLASDGCGCCAPSTPSATVSAPAVAAATDATPEGPTTYQVTGMTCGHCAGNVTEAVSALPQVDDVQVDLIAGGVSIVTVTGSVPLETVHRAIEETGYTVLS
>NZ_CP010451|3004795:3063156|3020054_3021023_+|WP_040968019.1|DBSCAN-SWA
MKAPLPIRDGLNPSRVRLPLDAAPIRAIDFVEYLISTQRHRNPADNAEALQARFDANLVVNHYGEPYAPDTMVQPDDDIWFYRMPAAERPIPYKIQVIHEDDDILVIDKPPYLATMPRGRHITETALVKMRVLTGNNDLTPAHRLDRLTSGVLVMVKKPELRGAYQTLFARREASKTYEAIAEFVPGLLDDGPAIWESRIEKERDIVQAFVVEGPVNARTELVSVTPVDDAEQSILEEMHGPLPRQARYVLAPSTGKTHQLRIHMRDFAAPILGDPLYPVLHAVDDEDYTTPMHLIARTLTFVDPQTNEERTFVSNRPTGSL
>NZ_CP010451|3004795:3063156|3035383_3035614_+|WP_040968025.1|DBSCAN-SWA
MLKHAVEGGRLTLSSRATWPLGTWATIFSMITWGCSLSNFVPLMLLAVGRLNQVDTLGLALMDPITLELHEGSRGG
>NZ_CP010451|3004795:3063156|3014027_3014852_-|WP_040968017.1|DBSCAN-SWA
MTATLSAESSRNGKKPRPRLSVSQVVGEILLTVGILALLFAYYEAYWTNVESGKLQESAGQKLDEDWNEARVNPRQKLTPELGEAFARMYVPAFGSDFNFAVIEGTDEEDLLAGPGRYVDSQMPGEAGNFAVAGHRVGKGAPFNDLGNLEVCDAIVVETYNSWDVYRVMPMSTNGADRAAEAADCFNETQVSRMAEGDYVNVSGRSITTPDRIDATYPTPGVFDTAVREGSEALLTLTTCHPQFSNAERMIVHAMLVEEIDKSSGERPAALEEN
>NZ_CP010451|3004795:3063156|3050176_3050467_+|WP_040968032.1|transposase|DBSCAN-SWA
MSNRRIFTEEFKAGAVQLVVSSGRSIKEVATELGIKEGTLGTWVRAWNTEHPDAGVDEPGPVEWAKYKALQAENAALKRENEFLGKASFFFAAKRL
>NZ_CP010451|3004795:3063156|3038368_3039661_-|WP_040968027.1|transposase|DBSCAN-SWA
MIADTICRTAELGLTITGASDAGDYTLIEADALDYTSTCPECFQPGVFRNHTHRMLIDLPIVGFPTKLFIRLPRYRCTNPTCKQKYFQAELSCADHGKKVTHRVTRWILQRLAIDRMSVHATAKALGLGWDLTCQLALDMCRELVYNDPHHLDGVYVIGVDEHKWSHNRAKHGDGFVTVIVDMTGHRYDSRCPARLLDVVPGRSADALRSWLGSRGEQFRNQIRIVSMDGFQGYATASKELIPSARRVMDPFHVVRLAGDKLTACRQRLQREKYQRRGLSQDPLYKNRKTLLTTHKWLSPRQQESLEQLWAYDKDYGVLKLAWLAYQAIIDCYQMGNKREAKKKMRTIIDQLRVLKGPNKELAQLGRSLFKRLGDVLAYFDVGVSNGPVEAINGRLEHLRGIALGFRNLNHYILRCLIHSGQLVHKINAL
>NZ_CP010451|3004795:3063156|3015083_3016352_+|WP_003862532.1|DBSCAN-SWA
MLDILIYPVSGVMKLWHLLLHNVAGLDDSLAWFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGKYDEASIRELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLGLYWALLRMARPEGGLENPVFQSIGFLTPEEVESFLAGRVSNVPLPAYVSMPTEQLEYLSTTQAEVLNFVLPLFITAAILTAINMAMSMYRSFQTNDYASGFSNGMLKFMIVMSILAPIFPLSLGLTGPFPTAIALYWVSNNLWTLLQTIIMMVILERKYPLTDDFKVHHLEQRDIYRAKQKEKRIFLWTRRKNRALMILTPWNASTLHATNVELTKTRTAEINEAKQARKEIANKRRETQREMNRAAMQRLKQRRAEVKAKKKGLIDASPNEDTPSENEETKLSSPQVEPTTTAEPNREPSQED
>NZ_CP010451|3004795:3063156|3033518_3034232_+|WP_040968229.1|DBSCAN-SWA
MSSYRPLESRLAGTSRATADNRTPCTGRLGTPRVFLMATDDVSKAYSSPTFDAEALLGTVISAEDPDRVLIEPWETGVDGVILDVGSGTGRWTGHLASLGHQIEGLEPATRLVELARQTHPSVTFHHGTITDLSDSPKRWAGLLAWYSLIHMDPGELPDALVALRMEVEDGGGLLMSFFSGPSLEPMYHPVATAYRWPLPELAQALETAGFQVTSSHWDPRFPHAYLTAEASKQNLA
>NZ_CP010451|3004795:3063156|3049429_3049636_+|WP_040968031.1|DBSCAN-SWA
MFKIRIIFPDGTDEEQDEHFDTEREAEEHGAYLASCYRQGNEILHMSNPGDYPLEDEDADYEVIEVDE
>NZ_CP010451|3004795:3063156|3004795_3005977_-|WP_034983145.1|transposase|DBSCAN-SWA
MDEQRAFDQGLKEENTLITDLTTCARLSHNKALRLIKLSKSTAYYRNKPRPCPAPKPVLQAVPAPTAPGVELAAPGVEPTPEPWQGKEPAVSSVRQALAEHERQFIVDAITAYPQLSVSGVFNMLFNKGIYRASLRTWWRVAKQHKLLHKDRVSALSPVKRSPTPRVKPRLEATQPGQVVCWDVTFLPSLVRGKTYALHLAIDLFSRKIVGAKVAPTENTSTAVELLTQVLADNPGVVTVHSDNGSAMTSTRVRRLLADHGVALSLIRPRVSDDNAFVESVFHTLKYRPFYPKVFASMDQARVWVEEFVVYYNTVHPHSGVAGHTPQSVFDGSWRAVHRLRVQALDAHYRQFPQRYVGQPVVQEVAGVVRLNGARDDGSVQERVGGVASLLSA
>NZ_CP010451|3004795:3063156|3049005_3049305_+|WP_034983357.1|DBSCAN-SWA
MTKQEYYDYSKTYEYNEESPYTGALADGVEEATILSGEVTWSADITWNESLEQYEIFKTWNDHDGHFSNMGEGPLEDDFLNDVYSFLQSKGIDSAEVTY
>NZ_CP010451|3004795:3063156|3030637_3031645_-|WP_040968228.1|integrase,transposase|DBSCAN-SWA
MEMWQIDGFIYTLHDTDLTRVTIYQILDDATRFDVGTCVFPANENSVDARTALEQAIAHFGAPHELLSDNGSAFNRMRQGYVGSLESYLATVGCLSITGKPGHPQTQGKNERSHRTLFRFLQAHQPHTLEECAHYIEQFRDHYNNRRPHQGLPNNLTPASAWEIVGCVEQQPPIDPVVLQQQADHYARRRIEKQSDVSLVRQEESVPVSKMQQTEQRRRVRRFGKKPVDPDVFTFAGNNQKVVFQGMRISVPRTMRDREFYRTVTATELGFWDAITGELELSIPLPVVAIARGKSYINSYNIRGVWMQHPTPLWQRKRNEAEKRFKSIDPGDLLR
>NZ_CP010451|3004795:3063156|3009171_3010734_-|WP_074508569.1|DBSCAN-SWA
MDSYSRAAMGSVLMALQFASYCIMHKICTIHIMSSSSPESATPQIKYCLLVGTLASAGITVSLAQTLVIPIIGRLPEIFNTTAANASWIITVTLLVGAVATPVMGRLADMYGKKKMMLISLVPFILGSVICAVSADLIPMIIGRGFQGLGSGLIPLGISLMHDLLPREKAGSAIALMSSSMGIGGALGLPLAAAIAQFASWRVLFWFTALVALTVGAVIWKAIPASPRIVRSGGFDYFGALGLAMGLIALLLAVSKGSEWGWRSALTIGLFVAALVILVGWGWFETRQKSPLIDLRTTIRETVLMTNIASILIGFTMYGMNLILPQVMQLPVILGYGLGQSMLQMGIWLIPMGLGMMLISNAGAAISAAHGPRVTLTIAGVVIAVGYALTATVLFTIGNRTPGGDADNALILTTLVLFSVCSLVVGIGIGLAFGSMPALIMGAVPATEKAAANGFNSLMRSLATTGSSAVIGAVLAGMMSGGVPTLGGFMTTLIIGCCAALVAAVISYFITTTTTVVEAK
>NZ_CP010451|3004795:3063156|3027810_3029214_+|WP_040968021.1|DBSCAN-SWA
MLERTQVFVDTSYLLASFYNSWETGARAQLEIDLPEVVGVLGRMIEQQLKQPVQRQMWYDGIPDSGPHRYQRALRTCDGVQLRAGQLIEWGERRTQKAVDTRLVADLVLAGVRGQCSDIVLVSGDADMIPGVQEAANAGLRVHLYGFGWDSMSSQLRHCCDTTTILDPREDFAECMQLQVLEGPLPPVVRVKPINDAEPIEDLDFTPVPGVASPFEEVSAKDEKFSPRPGEPAEALSEQVCEAQNEISKHEGQTADSVEITESFEGAEIKVTEFFGEPAVPVAESGVEAPTVPEAAKPTPAKPKTPKAEPQKQESPKPGTPKPKAPSPADIPPKAPADTEEHSEVEAEIEDSRPKIPSPSMMAPRRKLRSRYVPLPNEVWATAGFQTPYDVGQQYASWWFENAATSTQRDQAHLLSGGGLPPEIDRPLLQFACETLHEYTLTEAQRVALRDGFHSGIRGVLLNQRDS
>NZ_CP010451|3004795:3063156|3008511_3009147_+|WP_003858964.1|DBSCAN-SWA
MGIFEAIRAARAKTKAEIKAAEAKVKTEAKNKAKLDLKREKLLVQQEKNLLKVEEKGLKKRNKHELKMAKNILEQKRQGRLNKDKVKRWAGTARVLTPLLLPIIYRLSTEARDQVVKGRARRAGVTAEQLSQFAGHAAALKARIQGVRETAKNSGLPAGFVRDVEERLNELEAAANNSEFMSPQQRNRAHQSISRDLNQVSDQIQDRLLDK
>NZ_CP010451|3004795:3063156|3017844_3018750_-|WP_003862525.1|DBSCAN-SWA
MSTEDIVVVAVDGSDASKQAVRWAANTANKRGIPLRLASSYTMPQFLYAEGMVPPQELFDDLQAEALEKINEARDIAHEVAPEIKIGHTIAEGSPIDMLLEMSPDATMIVMGSRGLGGLSGMVMGSVSGAVVSHAKCPVVVVREDSAVNEDSKYGPVVVGVDGSEVSQQATEYAFAEAEARGAELVAVHTWMDMQVQASLAGLAAAQQQWDEVERQQTDMLIERLAPLVEKYPSVTVKKIITRDRPVRALAEASENAQLLVVGSHGRGGFKGMLLGSTSRALLQSAPCPMMVVRSPEKIKK
>NZ_CP010451|3004795:3063156|3053944_3056032_-|WP_040968035.1|DBSCAN-SWA
MSEHQHDHDPGHRTAPNGSPTTLPPTSAATHTQDHAHGSARWELWFAIAAGVTYTGGMIAEFALGLPMVGWPLAFFLATYFFGGFFTIRTAISSTLRGKFEVDFLMLVAAVGAALIGRWAEGAVLLFLFSLGHALEEYALSRASKSIEALAELAPRSALVRRGETEPVEVPVEELVVGDIVVIRPNSRIPSDGFVISGMSAVDQSAVTGESIPVEKEPVSDPTRTMHTVGTLPATNRVFAGTVNGSGLLEIEVTATAADSTLSKVVELVRTADQAASPTQQFIDRFQRWYVPAVILGVIATLLVSMFAFAQPFRDAFYLAMTVLVAASPCALAIATPAAVLAGVARAARAGVLVKGGAPLETLGRVEAIAFDKTGTLTWGAPRVTSLVPADDTSESELIPTLVSVESLSDHPLAAAIVRDLAPRVPETGRLVATDLSALTGRGITTTIDGERVEIGNLRMFDEQQLELPSSLAKAYAEARDSGQTLMIVRRGDRFLGVVGVMDASRAESAQVLNALRDTGVGHLVMISGDNQRVADAVGQEVGVDTAIGELLPEDKVTHITSLAKTYRPIAMIGDGVNDAPAMARADVGIAMGAAGSTVALETCDIALMSDDLGRIPFAVRLSRAASRIIRQNLIASLAIVVFLIIATFLGLNIGAVVLIHEGSTLIVVANALRLLNFQKGQEHAGIDHEEKPTH
>NZ_CP010451|3004795:3063156|3018886_3019876_-|WP_040968018.1|DBSCAN-SWA
MSSVVGEGPKPRLSVLDLVALSEGMTAGEAIAHSVRAAQIAEEHNYARFWVAEHHNSEGLASSATTLLMGHIAGHTSRIRVGSGGIMMPNHSALHVAEELGTLEAIYPGRIEAGLGRAPGTDPMTARELGRASSLVDDVLSTIVSLQNYLDTPEERPNIIAHPGINSCVPLFMLGSSLNGAAMAAKLDLPFAFASHFAPFQMGPAIASYRERAANPYVMAAANVLVCDTEEEAEFQISTLHQMFAGIVTNSRGKLAPPVRNLKDKLDPMIWKHIEDSLEMTFIGTAESVVLQLQEFADRYKLDEIITVTYSYDPEVRFRSIAALGTAWN
>NZ_CP010451|3004795:3063156|3052105_3052714_-|WP_080506466.1|transposase|DBSCAN-SWA
MTERGVPVDHTTIYRWVQKYAPELDKKTRWYRQVPDWQARSWRVDETYIRVGGKWCYLYRAITAGGQTLDFYLSPKRNVAAAKRFLAKTLRSNKSAGYPRVISTDKAPSLARAISELKAEGVCPSTVEHRRVKYLNNVIEGDHGRLKRILGPKGAFKNRTSAYRTLKGMEAMHSLRKGQGTMFAYGHPNPDAVIVSRVFETA
>NZ_CP010451|3004795:3063156|3036478_3036802_-|WP_003859507.1|DBSCAN-SWA
MTYTIAQPCVDVLDRACVEECPVDCIYEGKRMLYIHPDECVDCGACEPVCPVEAIFYEDDVPHEWWDYTGANAAFFDDLGSPGGAASLGPQDFDAQLIAALPPQNQN
>NZ_CP010451|3004795:3063156|3011249_3011888_-|WP_003862544.1|DBSCAN-SWA
MIRVLLADDHEIVRLGLRAVLESAEDIEVVGEVSTAEGAVQAAQEGGIDVILMDLRFGPGVQGTQVSTGADATAAIKRNIDNPPKVLVVTNYDTDTDILGAIEAGALGYLLKDAPPSELLAAVRSAAEGDSTLSPMVANRLMTRVRTPKTSLTPRELEVLKLVAGGSSNRDIGRILFLSEATVKSHLVHIYDKLGVRSRTSAVAAAREQGLL
>NZ_CP010451|3004795:3063156|3037779_3038007_-|WP_024127858.1|DBSCAN-SWA
MTTGEGTHGCDYFTSLFLLPKLCNSTARKTIGVIQPDAEVRETLRPGYATNADSLTMAGHVVAIEFATVAAANNY
>NZ_CP010451|3004795:3063156|3013319_3013871_+|WP_040968015.1|DBSCAN-SWA
MRRTLPTILAASIMLTACTPAEPEATPETTTEATPEVITDGLPIDAMPAVERTAQTACPYLGTDWVADTNGQRVTGYGTDERFSTPSCVFYSYPEEPQLTVIVRDMATTDDAIAVVDWAAPIDSTEPAEEPAGWSGGRRGGNDTSGALYAVQNGPTAVIVFTNQDQSLKAQLIAEEAIQNLGL
>NZ_CP010451|3004795:3063156|3032737_3032860_-|WP_080770725.1|DBSCAN-SWA
MLGYTFVIFILAPFLILTGIAMAPAIRSRFPWYVKLFGGH
>NZ_CP010451|3004795:3063156|3017102_3017366_-|WP_003862528.1|DBSCAN-SWA
MLALGWITWIIIGGLAGWIASKIKGTDAQQGILLNIVVGIIGGLLGGWLLGVFGVDVAGGGLIFSFITCLIGAVILLTIVQFFTRKK
>NZ_CP010451|3004795:3063156|3006901_3008317_-|WP_074508568.1|DBSCAN-SWA
MQRRARREVGLAEVLDRLPEQPKKRGRIPFTRADLDNDAELAEFDTLEAIAAGDTLITGAVFTGTLEGVAWEVQVDVLVRNPDGTYMPVMVSNHRVARPDPHKTMQGIAVTRLGLGQPLEVKATLRHHTIDGYRLTLALMGLEEAGAAPESSIGAVVGQDRDWAYLVDVTRYIPAAHRALLTPAPTAPRRVKECATCRFWPKCEPELKAADDISLFLTGDRADTYREKGINTTTALIDANLGEISHVAAAWRAEIPVLRREAHTSAPRFDVEIDVDVEAYLDLGAYLWGAWDGKTYIPFVIWSDLGEAAEGENFARFWSWLKSRRDKARQQGQTFGVFCYASNGENHWMLSTARRFFGKVKGVPDEQEIRSFISSDQWNDMFAVARSQLVGPGGLGLKQLAPAAGFHWEEEDFAGEDSLHAYLIASTAAEPEAKAARAQLLSYNGDDCRATAAVRHWLRQGARTAPVLGSI
>NZ_CP010451|3004795:3063156|3033124_3033331_-|WP_040968024.1|DBSCAN-SWA
MEINPDFPLWLRATHLINFVLIGMLLRSGWEILSSMPRLWWRNDCASGTEWLRFTKCKLPKEEGSTPH
>NZ_CP010451|3004795:3063156|3031703_3032642_-|WP_040968023.1|DBSCAN-SWA
MVHMVFGDMNTDRAAQAYIIVITTIVMVVLFWIVLSYWSLADRARAQRFTASITEIGRKIFLNRLRPRMSRQNTYTDKDISQFHWTNGLPPTDDESPEWIAARDNEWEGYTITLGDDPNGTEKTITLDDLRELPQTSYVAVHTCMQGWSATARWTGVRLRDVLCHDLVHTLDLHHRHSPRLLTIEIMPKPLPPETRCKIIDFDLFAPNSPSIEEFCSRLKISRRSFYNIRNRYQQDASAALHPRSSAPITSRRTYDESITSILLAIRAPPESPRMGIRSDLYPIRRHRHRGTDCTDSIRLNYRLLVTRCRSC
>NZ_CP010451|3004795:3063156|3044501_3045224_-|WP_003859491.1|DBSCAN-SWA
MADRTPTTATPPGRVLVVDDEQPLAQMVASYLIRAGFDTRQAHTGTQAVDEARRFSPDVVVLDLGLPELDGLEVCRRIRTFSDCYILMLTARGSEDDKISGLTLGADDYITKPFSIRELVTRVHAVLRRPRTSTTPPQVTTPLIVGDLILDPVAHQVRVGETTVELTRTEFELLVALALRPGQVLTRHDLVTEVWDTTWVGDERIVDVHIGNLRRKLGTDTRGRGFIDTVRGVGYRVGQP
>NZ_CP010451|3004795:3063156|3059767_3060352_-|WP_003860216.1|DBSCAN-SWA
MIISPMLPRRVLATVVAVGALTVVATPVALAHDSVIGGNPADGEVVEEFPRSIELKFSGLPQEGFSTVAITDQDSGDLLFSGEPTIDGRLVTLDLPADVSGGPGDYTVGFQILSSDGHATRSATTFTVAGDAQTTATPTGADAKPVEETTAVENTAEGDTSIVSNPIVLTLAGLALFGVIAGAIVLAVRSRDRR
>NZ_CP010451|3004795:3063156|3045627_3046203_+|WP_003859489.1|DBSCAN-SWA
MKRAAIAAAALALALTGCSAADPEPTADGTVSQDTFLTTHGLAAMDAVEIIDHLDRQKVTERPTDLIASVRADELLLSSDDQEVVVDLPDNQTYVSVAPYITSTHDCFYHSLTTCLGELDNEDIQVTITDEATGEVLIDEQTTTFDNGFVGFWLPDDATGTIEITHQGRTGVTEFSTTEDGATCVTDLRLT
>NZ_CP010451|3004795:3063156|3035628_3035925_-|WP_040968026.1|DBSCAN-SWA
MESAGRPRVTLLEEGALFETKRMEAASGISWPRHRASTESVLVVTEGRCIVQFSAEDRGVSAGDSLVIPADIWHEIVADPEFKAVHIMPKEIRFTFST
>NZ_CP010451|3004795:3063156|3049765_3050035_-|WP_034983353.1|DBSCAN-SWA
MSSTKIVRGIAKIVLELFFENAKELLWRILGHVHAHGVERLGTISVLARFPLMQANAVYVVSMVTIKETAHTDRAMRIVEDFHDATQNL
>NZ_CP010451|3004795:3063156|3051010_3051217_+|WP_040968033.1|DBSCAN-SWA
MINNRLEAAVADMAARVHEQISAATASHVLAAYKPILSTEKIREMTCVKIPNPTEHATQNIRMYRIRQ
>NZ_CP010451|3004795:3063156|3011986_3013321_-|WP_011015505.1|DBSCAN-SWA
MQSSLDRVSETGRNELDVETLVKKGNQPGAMSYRNSIHILTASLLVVGLGASARLTLPMFALSCVLLFVWGFLYFYGSTKRVDLSHGMQLGWLFVLTLVWIFMVPIVPVSIYLLFPLFFLYLQVMPDVRGIIAILGATAIAIASQYSVGLTFGGVMGPVVSAIVTVAIDYAFRTLWRVNNEKQELIDQLIETRSQLAVTERNAGIAAERQRIAHEIHDTVAQGLSSIQMLLHVSEQEILVAEMEEKPKEAIVKKMRLARQTASDNLSEARAMIAALQPAALSKTSLEAALHRVTEPLLGINFVISVDGDVRQLPMKTEATLLRIAQGAIGNVAKHSEAKNCHVTLTYEDTEVRLDVVDDGVGFEPSEVSSTPAGLGHIGLTALQQRAMELHGEVIVESAYGQGTAVSAALPVEPPEGFVGAPVLADSDSSATGEVELSSPTDDE
>NZ_CP010451|3004795:3063156|3034472_3035195_-|WP_011015522.1|DBSCAN-SWA
MIISTNTAHPLHEPHVPSHHNRMNTLRAGVLGANDGIVSIAALLLGVIATGASDTVVFGAGLASTIAGAVSMALGEYVSVSSQRDTERVLIAKEAKELAEDPTAEHVELSEILHSYGISPETANQAATEIGQGDALGAHLQLELGIDNEQLTSPLAAAFSSAVAFLLGALLPMVSVFIAPAGWDAGVVFVVTLLVLAVTGFISAQISGTSPMRACGRLVIGGALGLALTYGVGVLFGAAV
>NZ_CP010451|3004795:3063156|3056155_3057196_-|WP_040968036.1|DBSCAN-SWA
MAVSSTGERRYGRAPQKKGWRTFLRPGWVFGVLAIIAFSYVAFTFLAPWQLSRDSTIVERNEQIEAAFEVEPVPAEEIFDAQGSIEPGEEWARVILQGHYLPEDEVLMRNRPVDSSPAFHALTPFQLNSGEIILVNRGFNPPLEGGVPPMDTAPAGEQSIVGHARFTEQTPMSPPIEDQGYRQVYGINTAQIAEVTGRDLAEDYVQLAEGQAGEINAIPVPMLDRGSHLSYAFQWIAFGIMAPLGLGYFIWAELKERRRVRREEAELADGSASSQQTGDSQDEETDSDPVGALHTTHPENDTQGLAHAQATTSASSGARARMLHDRYGDSQPNHSRKFTNRRHERF
>NZ_CP010451|3004795:3063156|3060610_3062671_+|WP_046552218.1|DBSCAN-SWA
MRAEAAWTAKWTQMTHPVNDTPTATDTTTGTTPTIGSRPQERVRPTWPLYLLFFAVAGAIGGTVAYSFLGESLAALGIPNPGIATTFGLPFFRAVGWMLAALSAGSFLFAAFLISPRLPGGDHDRLHQASLSVDGHLASRTGAVAAICFGLIALLMIPLVLSDVSGTPLAQTLGLETLTVAVEQVAMAQVWLIVALIALVTGCTGLMSRAWITQPLLLLGSILMIIPLGLTGHSSSGGNHDHGTNSYLWHLVFLVLWVGGLMALLAHGRRLGPDLDIALRRYSMIALVSIIVMAVSGLVNAAIRIELTDLLTTRYGLIIVAKTIGVIILGVFGWIHRAWVIPQVQANPADRRLFRQVAIVEVLVMAAVTGIAITMGRTPPPPPRIPNLSQMVTKLGYELSEKPTILNVWGMWRFDLLFGALALLLAVGYLAAVWRTRQTGHTWSSTPTAWWLAGCVTLLVTMSSGIGLNMPAVFSVHMVGHIILSLVIPIFLVMGAPLTLLMTAFAPGAPGRPNIHDWVRAFTRSRLVGVITHPVVNTLQFLVFFYVMYLFIPLYELLISKYAGQLIMNTVLLVSGCFYVWGMLGPDPIPRRRPATVRLGWLVASLPVHLLVGVYLLRLDTILGEEFYRSLLLPWDIDLLADQHAAVTAWAIGGIPLLLAIILLIRQWRDIRRRPHDQAPLAVPAE
>NZ_CP010451|3004795:3063156|3029273_3030149_-|WP_040968022.1|DBSCAN-SWA
MANPLSKGWKYLMASFDNKIDENADPKIQIQQATEAAQKQHQQIMQHASQIIGQQKQLEMKLNRLVTDRDKLQEQARQAIQVADKSANEGDSVKAQEFNNTAEVFASQLVAVEQQLEQTTALHQQAEVAAKDAVAKSKESEMRLKEQMSQIDALRAQADQAKMQESVTKSMDSLNQFGTQDSSVPTLDAVREKIERRYADALGAQELTQNTVSDRMAEIAQSGTDMRASARLAELRAEELGTSATPKGQLEAGVEDAEELIDETSTPSATPETASPEADAPEASADESEKK
>NZ_CP010451|3004795:3063156|3039927_3040590_-|WP_011015525.1|DBSCAN-SWA
MKRTITIAALALTSTLVLSACADNTEGENTDTTTIATTSAPDTTETTGATTDPETETGAAGEVSAEHNDADIMFAQMMIPHHQQAVEMSEILLAKDDIPAEVIEFTQGVIDAQGPEIDRMNTMLETWEEDPVTGDMGEMDHGGMSGMMSEEDMTALEDAQGTEAARLYLEQMTAHHEGAVDMARDEVTDGQNPQAIALAEQVIEDQEAEIAEMEQMLNEL
>NZ_CP010451|3004795:3063156|3010693_3011152_+|WP_011898073.1|DBSCAN-SWA
MSTDPIAALEYESIIFARHRNQYTGQAGTNAGVLDSSGYNLLTLLQLRGPSTIGELSAITGLDASTLNRQTKALLTKGFVERIPDPDGGIARKFHPTDLGNELLNEERTSSQEKYAELLSDWPEEDLRTFVKLLEKLNKAVETRVGKHWPRP
>NZ_CP010451|3004795:3063156|3032870_3033125_-|WP_034983364.1|DBSCAN-SWA
MDEKSLSPLIGLPGRENIGLGRHWHGLSTMLRVLNGIVYVVLLFATGLWQRIIPTSWDVFPEAWETLKVYLGFRAPGIEHFTPL
>NZ_CP010451|3004795:3063156|3062787_3063156_+|WP_003860220.1|transposase|DBSCAN-SWA
MSRFQLLTDDQWALISDKLPHRIGKKGRPFSDPRLMLEGIIYRLRCGIPWRDLPECFGSWHTVYHWYNRMAKDGIFDEIVTTLIAAADHQGLVDWSVSIDSTISRAHQHATNITRHTGGFVE
>NZ_CP010451|3004795:3063156|3040644_3042864_-|WP_040968028.1|DBSCAN-SWA
MSTPHHHGDHPAPETDHTHHPNHAGHEHHADAATHGHAMPHDHPHSAVDEEHQVHSHGEHAGHSAAMFRDRFWWSLILSVPVVFFSPMFADLLGYNIPEIPGAYWIPPVLGTIIFLYGGTPFLKGAMTELKSRQPGMMLLIAMAITVAFIASWVTTLGLGGFHLDFWWELALLVTIMLLGHWLEMRALGAASSALDALAALLPDEAEKVVDGTTRTVAISELAVDDVVLVRAGARVPADGTIIDGAAEFDEAMITGESRPVYRDTGETVVAGTVATDNTVRIRVEATGGDTALAGIQRMVADAQASSSRAQALADRAAAFLFWFALIVALITAVVWTIIGSPDDAVVRAVTVLIIACPHALGLAIPLVIAISSERAAKSGVLIKDRMALEHMRTIDVVLFDKTGTLTEGAHAVTGVAPATGIAEGELLALAAAAEADSEHPVARAIVTAAAAHPEASQRQLRATGFTAASGRGIRATVDGAEILVGGPNMLREFSLTTPGELADITGSWAQRGAGVLHVVRDGEIIGAVAVEDKIRPESRAAVRALQARGVKVAMITGDATQVAQAVGKDLGIDEVFAEVLPQDKDTKVTQLQERGLSVAMVGDGVNDAPALARAEVGIAIGAGTDVAMESAGVVLASDDPRAVLSMIELSHASYRKMVQNLVWATGYNIVAVPLAAGVLAPIGVLLPPAAAAILMSLSTIIVALNAQLLRRIDLDPAHLAPTDGKEEKAAVSSAATVR
>NZ_CP010451|3004795:3063156|3027236_3027602_-|WP_040968020.1|DBSCAN-SWA
MTAPLYKQIASLIEDSIVDGTLSIDQRVPSTNELAAFHRINPATARNGLTLLVEAGILYKKRGIGMFVSAQAPALIRERRDAAFAATYVAPLIDESIHLGFTRARIHALLDQVAESRGLYK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034983145.1|3004795_3005977_-|transposase	IS3 family transposase	NA	NA	NA	NA
WP_034983267.1|3005979_3006285_-	hypothetical protein	NA	NA	NA	NA
WP_074508568.1|3006901_3008317_-	TM0106 family RecB-like putative nuclease	NA	NA	NA	NA
WP_003858964.1|3008511_3009147_+	hypothetical protein	NA	NA	NA	NA
WP_074508569.1|3009171_3010734_-	MFS transporter	NA	NA	NA	NA
WP_011898073.1|3010693_3011152_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003862544.1|3011249_3011888_-	response regulator transcription factor	NA	NA	NA	NA
WP_011015505.1|3011986_3013321_-	sensor histidine kinase	NA	NA	NA	NA
WP_040968015.1|3013319_3013871_+	DUF2020 domain-containing protein	NA	NA	NA	NA
WP_040968016.1|3013874_3014027_-	hypothetical protein	NA	NA	NA	NA
WP_040968017.1|3014027_3014852_-	sortase	NA	NA	NA	NA
WP_003862532.1|3015083_3016352_+	membrane protein insertase YidC	NA	NA	NA	NA
WP_034983244.1|3016278_3016920_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003862528.1|3017102_3017366_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_003862525.1|3017844_3018750_-	universal stress protein	NA	NA	NA	NA
WP_040968018.1|3018886_3019876_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_003858997.1|3019885_3020074_-	hypothetical protein	NA	NA	NA	NA
WP_040968019.1|3020054_3021023_+	23S rRNA pseudouridylate synthase	NA	NA	NA	NA
3021040:3021055	attL	NA	NA	NA	NA
WP_040968020.1|3027236_3027602_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_040968021.1|3027810_3029214_+	NYN domain-containing protein	NA	NA	NA	NA
WP_040968022.1|3029273_3030149_-	PspA/IM30 family protein	NA	NA	NA	NA
WP_040968228.1|3030637_3031645_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_040968023.1|3031703_3032642_-	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_080770725.1|3032737_3032860_-	hypothetical protein	NA	NA	NA	NA
WP_034983364.1|3032870_3033125_-	hypothetical protein	NA	NA	NA	NA
WP_040968024.1|3033124_3033331_-	hypothetical protein	NA	NA	NA	NA
WP_040968229.1|3033518_3034232_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011015522.1|3034472_3035195_-	VIT family protein	NA	NA	NA	NA
WP_040968025.1|3035383_3035614_+	hypothetical protein	NA	NA	NA	NA
WP_040968026.1|3035628_3035925_-	cupin domain-containing protein	NA	NA	NA	NA
WP_003859507.1|3036478_3036802_-	ferredoxin family protein	NA	NA	NA	NA
WP_003859505.1|3037073_3037409_-	cupin domain-containing protein	NA	NA	NA	NA
WP_024127858.1|3037779_3038007_-	hypothetical protein	NA	NA	NA	NA
WP_040968027.1|3038368_3039661_-|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	9.8e-83	42.2
WP_011015525.1|3039927_3040590_-	DUF305 domain-containing protein	NA	NA	NA	NA
WP_040968028.1|3040644_3042864_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.3e-55	29.6
WP_006284595.1|3042914_3043247_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_040968029.1|3043305_3044505_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	7.1e-27	27.3
WP_003859491.1|3044501_3045224_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.2e-39	38.4
WP_003859489.1|3045627_3046203_+	hypothetical protein	NA	NA	NA	NA
WP_034983357.1|3049005_3049305_+	hypothetical protein	NA	NA	NA	NA
WP_040968031.1|3049429_3049636_+	hypothetical protein	NA	NA	NA	NA
WP_034983353.1|3049765_3050035_-	hypothetical protein	NA	NA	NA	NA
WP_040968032.1|3050176_3050467_+|transposase	transposase	NA	NA	NA	NA
WP_040968033.1|3051010_3051217_+	hypothetical protein	NA	NA	NA	NA
WP_040968034.1|3051492_3052059_-	hypothetical protein	NA	NA	NA	NA
WP_080506466.1|3052105_3052714_-|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.4e-60	56.5
WP_040968035.1|3053944_3056032_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.0e-113	39.3
WP_040968036.1|3056155_3057196_-	SURF1 family protein	NA	NA	NA	NA
WP_040968232.1|3057258_3059193_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.0e-91	36.8
WP_011896442.1|3059225_3059591_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003860216.1|3059767_3060352_-	copper resistance protein C	NA	NA	NA	NA
WP_046552218.1|3060610_3062671_+	bifunctional copper resistance protein CopD/cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_003860220.1|3062787_3063156_+|transposase	transposase	A0A0N9SHJ4	Paenibacillus_phage	1.4e-18	44.5
3066063:3066078	attR	NA	NA	NA	NA