CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP014582	Bordetella bronchiseptica strain S798	10 crisprs	csa3,DEDDh,DinG,cas3	2	1	2	0

1. NZ_AP014582

CRISPR-Cas detection and classification

Crispr_ID: NZ_AP014582_1

• CRISPR_ID: NZ_AP014582_1
• CRISPR_location: 484698-484799
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP014582_1

Consensus_repeat	Method
CTGCGGCCAGGGAGCCTGTCCCCGC	CRISPRCasFinder

spacers of NZ_AP014582_1

>1.1|484723|52|NZ_AP014582|CRISPRCasFinder
CGGGGGAGCGACACCTGCGGCCAGGGAGCCTGTCCCCGCCGGGGAGCGACAT

CRISPR arrays and Neighbor proteins around NZ_AP014582_1

CRISPR arrays

The CRISPR arrays of NZ_AP014582_1

>merge|NZ_AP014582|1|484698-484799|CRISPRCasFinder
CTGCGGCCAGGGAGCCTGTCCCCGCCGGGGGAGCGACACCTGCGGCCAGGGAGCCTGTCCCCGCCGGGGAGCGACATCTGCGGCCAGGGAGCCTGTCCCCGC

>NZ_AP014582|1|1|484698-484799|CRISPRCasFinder
CTGCGGCCAGGGAGCCTGTCCCCGC	CGGGGGAGCGACACCTGCGGCCAGGGAGCCTGTCCCCGCCGGGGAGCGACAT
CTGCGGCCAGGGAGCCTGTCCCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014582.1|WP_003819124.1|467385_468045_-|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319787
NZ_AP014582.1|WP_033451607.1|486092_487646_+|acyl--CoA-ligase	unknown	unknown	gnl|CDD|223395
NZ_AP014582.1|WP_003807742.1|464801_465662_+|exported-protein	unknown	unknown	gnl|CDD|259799
NZ_AP014582.1|WP_033451560.1|468136_469045_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176168
NZ_AP014582.1|WP_010925819.1|493687_494164_+|MaoC-family-dehydratase	unknown	unknown	gnl|CDD|239535
NZ_AP014582.1|WP_010925816.1|488417_489182_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|119339
NZ_AP014582.1|WP_050484259.1|490695_491250_+|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176248
NZ_AP014582.1|WP_080772873.1|469537_476266_+|autotransporter-associated-beta-strand-repeat-containing-protein	unknown	unknown	gnl|CDD|273608
NZ_AP014582.1|WP_003807755.1|487653_488394_+|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_AP014582.1|WP_003807744.1|466213_467359_-|DSD1-family-PLP-dependent-enzyme	unknown	unknown	gnl|CDD|143487
NZ_AP014582.1|WP_003807750.1|476543_476675_+|entericidin-A/B-family-lipoprotein	unknown	unknown	gnl|CDD|227797
NZ_AP014582.1|WP_003807743.1|465737_466073_-|YegP-family-protein	unknown	unknown	gnl|CDD|377831
NZ_AP014582.1|WP_015064629.1|469041_469224_+|DUF3596-domain-containing-protein	unknown	unknown	gnl|CDD|371934
NZ_AP014582.1|WP_003807753.1|485080_486058_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270234
NZ_AP014582.1|WP_003807765.1|491341_492595_+|CoA-transferase	unknown	unknown	gnl|CDD|367110
NZ_AP014582.1|WP_015064624.1|492572_493535_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176131
NZ_AP014582.1|WP_033451571.1|489615_490596_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270296
NZ_AP014582.1|WP_003807759.1|489226_489562_+|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|223672
NZ_AP014582.1|WP_144402442.1|477121_484021_+|autotransporter-BatB	unknown	unknown	gnl|CDD|273608
NZ_AP014582.1|WP_003807752.1|484072_484654_+|ureidoglycolate-lyase	unknown	unknown	gnl|CDD|380432

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP014582.1|WP_003819124.1|467385_468045_-|HAD-IA-family-hydrolase	gnl|CDD|319787	cd02588, HAD_L2-DEX, L-2-haloacid dehalogenase. L-2-Haloacid dehalogenase catalyzes the hydrolytic dehalogenation of L-2-haloacids to produce the corresponding D-2-hydroxyacids with an inversion of the C2-configuration. 2-haloacid dehalogenases are of interest for their potential to degrade recalcitrant halogenated environmental pollutants and their use in the synthesis of industrial chemicals. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.90626e-33
NZ_AP014582.1|WP_033451607.1|486092_487646_+|acyl--CoA-ligase	gnl|CDD|223395	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.43938e-132
NZ_AP014582.1|WP_003807742.1|464801_465662_+|exported-protein	gnl|CDD|259799	cd03401, SPFH_prohibitin, Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model characterizes proteins similar to prohibitin (a lipid raft-associated integral membrane protein). Individual proteins of the SPFH (band 7) domain superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. These microdomains, in addition to being stable scaffolds, may also be dynamic units with their own regulatory functions. Prohibitin is a mitochondrial inner-membrane protein which may act as a chaperone for the stabilization of mitochondrial proteins. Human prohibitin forms a hetero-oligomeric complex with Bap-37 (prohibitin 2, an SPFH domain carrying homolog). This complex may protect non-assembled membrane proteins against proteolysis by the m-AAA protease. Prohibitin and Bap-37 yeast homologs have been implicated in yeast longevity and in the maintenance of mitochondrial morphology.	2.88817e-48
NZ_AP014582.1|WP_033451560.1|468136_469045_+|LysR-family-transcriptional-regulator	gnl|CDD|176168	cd08479, PBP2_CrgA_like_9, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 9. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.49194e-92
NZ_AP014582.1|WP_010925819.1|493687_494164_+|MaoC-family-dehydratase	gnl|CDD|239535	cd03451, FkbR2, FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown.	1.58721e-71
NZ_AP014582.1|WP_010925816.1|488417_489182_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	6.87831e-58
NZ_AP014582.1|WP_050484259.1|490695_491250_+|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176248	cd08288, MDR_yhdh, Yhdh putative quinone oxidoreductases. Yhdh putative quinone oxidoreductases (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.86669e-58
NZ_AP014582.1|WP_080772873.1|469537_476266_+|autotransporter-associated-beta-strand-repeat-containing-protein	gnl|CDD|273608	TIGR01414, Contains:_AIDA-I_translocator, outer membrane autotransporter barrel domain. A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	1.2096e-44
NZ_AP014582.1|WP_003807755.1|487653_488394_+|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	4.17717e-46
NZ_AP014582.1|WP_003807744.1|466213_467359_-|DSD1-family-PLP-dependent-enzyme	gnl|CDD|143487	cd06812, PLPDE_III_DSD_D-TA_like_1, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes Similar to D-Serine Dehydratase and D-Threonine Aldolase, Unknown Group 1. This subfamily is composed of uncharacterized bacterial proteins with similarity to eukaryotic D-serine dehydratases (DSD) and D-threonine aldolases (D-TA). DSD catalyzes the dehydration of D-serine to aminoacrylate, which is rapidly hydrolyzed to pyruvate and ammonia. D-TA reversibly catalyzes the aldol cleavage of D-threonine into glycine and acetaldehyde, and the synthesis of D-threonine from glycine and acetaldehyde. DSD and D-TA are fold type III PLP-dependent enzymes, similar to bacterial alanine racemase (AR), which contains an N-terminal PLP-binding TIM barrel domain and a C-terminal beta-sandwich domain. AR exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Based on their similarity to AR, it is possible members of this family also form dimers in solution.	0
NZ_AP014582.1|WP_003807750.1|476543_476675_+|entericidin-A/B-family-lipoprotein	gnl|CDD|227797	COG5510, COG5510, Predicted small secreted protein [Function unknown].	1.86823e-05
NZ_AP014582.1|WP_003807743.1|465737_466073_-|YegP-family-protein	gnl|CDD|377831	pfam07411, DUF1508, Domain of unknown function (DUF1508). This family represents a series of bacterial domains of unknown function of around 50 residues in length. Members of this family are often found as tandem repeats and in some cases represent the whole protein. All member proteins are described as being hypothetical.	1.7869e-18
NZ_AP014582.1|WP_015064629.1|469041_469224_+|DUF3596-domain-containing-protein	gnl|CDD|371934	pfam12167, Arm-DNA-bind_2, Arm DNA-binding domain. This domain is found at the N-terminus of various phage integrases. The domain binds to DNA.	5.99489e-08
NZ_AP014582.1|WP_003807753.1|485080_486058_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl|CDD|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	8.51184e-99
NZ_AP014582.1|WP_003807765.1|491341_492595_+|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	5.83088e-144
NZ_AP014582.1|WP_015064624.1|492572_493535_-|LysR-family-transcriptional-regulator	gnl|CDD|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.47076e-59
NZ_AP014582.1|WP_033451571.1|489615_490596_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl|CDD|270296	cd13578, PBP2_Bug27, Aromatic solutes transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. Bug27 binds non-carboxylated solute nicotinamide, in contrast to BugD (aspartic acid transporter) and BugE (glutamate transporter) which both bind aliphatic carboxylated ligands. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity.	7.38592e-131
NZ_AP014582.1|WP_003807759.1|489226_489562_+|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	1.70453e-16
NZ_AP014582.1|WP_144402442.1|477121_484021_+|autotransporter-BatB	gnl|CDD|273608	TIGR01414, Contains:_AIDA-I_translocator, outer membrane autotransporter barrel domain. A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	4.78804e-40
NZ_AP014582.1|WP_003807752.1|484072_484654_+|ureidoglycolate-lyase	gnl|CDD|380432	cd20298, cupin_UAH, ureidoglycolate amidohydrolase (UAH) and related proteins, cupin domain. This family includes the cupin-fold protein, ureidoglycolate hydrolase (AllA; EC 3.5.3.19), which is involved in the breakdown of allantoin under aerobic conditions. Allantoin is the key intermediate of nitrogen fixation in bacteria, and its degradation occurs in several steps. AllA is involved in the third step of this pathway which consists of hydrolysis of (S)-ureidoglycolate to yield glyoxylate, ammonia, and CO2. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.40124e-15

Protein sequences

>NZ_AP014582.1|WP_003807752.1|484072_484654_+|ureidoglycolate-lyase
MPTTMPALRPQVLTEAAFAPYGWMLGKPLPAGGDVPRFSNPATDFWQEHVFDTGVGAGRETEVLWVNYRVSQPGFDTLEKHLLTQQAIVPLTGAIVQIVARSAFDGSPDLASLAAFVVPPGQGICMRPGCWHATRISGGEVTCLMLTRRSTTLDLVRHLHGEPARESEIVAIVPHGLDLPARPTTEGPSPHGR
>NZ_AP014582.1|WP_144402442.1|477121_484021_+|autotransporter-BatB
MRRLKAQAFEGRRSRPAGHGVAPTLLALALGFQGTAAWANCTTSGSSTTCTAAGGAHGATVGGGSTGHNKQVTVQAGARIEAGDKAAISVGNNSQVQIQGGAVVQSTVNTAASGQYAKTLEAASNNNISIQEGAQLLAKGSASQSSALGLSGAGNTVTNRGTIRADNAAAIWVTANTAGANTIDNYGTIETVLNGGYANAIGSTRNNNATGAGVTVRNHANGRIVGNVKFEAGDDSVILDGGSTITGSLNGGSGNNSLTLKAGDGTLGRAIRNFGTITKQEAGTWTLNGQVGRNDNNLKSTVKVEGGTLALRGDNSGATQGGVLQVSAGATADVTAASAMQSISNAGTVQFTQDSNAAYAGVLSGTGSIVKRGGGDLTLTGNNTHTGKVVVEAGSLSVSAANNLGGAGSSVQLKGGALALKKTIAVNRGLTLDSGAQTLIIEPGTTTTWQGQVSGAGKLVTQGGTLVLEHASNTYSGGTEINNGTLRAAHDASLGSGTLALKNSQLAATDSFTATRALTLAGNESIDVAATKILSWNGEISGAGTLVKEGQGTLLLRGTNQQNGGTTVNAGTLQISRDANLGRGALALNDGTLQSTGSFATSRAATLRGQATMEVDASHTVTWNGELSGGGMLRKSGQGTLALAGANTYSGGTVVEAGALRAGHEDNLGRGAITLQGGDLLAGGSFSSNRDLTLVRGSLDVARDATLTWSGAISGAGDLVKTGDGTLALTGVNEYAGQTVLRQGKLRVAREESLGGGALVLENNTVFESAGSYAIGRRVTLKGAPKVATPAGDTLEWRGTVDGDGKLYKQGGGTLVLSGNNTYAKGVEVWGGVVQVSRDQNLGAANGAVTLNGGGLAANGDFTSNRQLELTAGAKAIDVAAGKDVTWRGVVNGAGALTKAGDGTLRLEGVNTYTGGTRLQGGTVQVSRDNNLGQAAGAVTFDGGRLASTGSFATARAATLNNAGQIDTAQGTTLTWNGAIGGKGELRKQGAGTLVLGGANTYQGDTRVEAGTLQVSADANLGQGAVHLHDSRLATTGTFATSRRLELTGRGTVQAAAAATLDWRGTVAGAGTLVKEGAGTLVLAGDNQHAGGTEVRAGTLQVSRATNLGPGALALENAALATTASFTATQAATLTGNAAIDTAAGTTLGWEGAIGGTGSLHKKGEGKLVLVKDNHHDGGTTIHAGTLQVSRDANLGSGQSAVTLDGGALAVSAGFSSGREIVVGAGHGALSVAGGHTLQWQGQVGGAGTLTKTGDGTLVLEHDNTHAGGTRVTGGVLRVSRDENLGEAHGMLTLDGGTLSATAGFASRRNATVGNGGGRIVVADSATLDLQGDVAGAGRLVKEGAGTLALGGTNTYAGGTVVEAGTLRVARDANLGGGALTLNNSRLHATAGFATGRDATLTGRASIDTDNRATLQWRGTVDGAGTLVKQGAGTLVLDGDNRYAGGTEVNAGTLQVARDANLGAGDVALNGSRLAATASFATARTATLSGAAAIDTADGATLDWNGLLDGDGALVKQGNGTLALAAANRYGGGTIVKAGAVRIARDANLGRAGTGVTLDGGALATTADLATGRAATLGAAHGTLDVAAGTRLDWNGAIGGAGALTKTGAGTLALNHDNQHAGGTLVHGGTLRIARDANLGAAGTAVTLDGGTLATTASLALDRALRVGARNGVLLPDAGTTLDWRGVVAGAGKLTKAGPGMLVLSADNRHGGGTAVTGGTLQVSRDANLGAAAGALTLDGGTLLSTASFASARAATLDAAGGTFVTRDGTRLDWDGAIGGAGGLVKEGAGELRLGNANTYQGPTRIAAGRLAVNGSIASPVTVEQAGVLGGTGRIVGDVANRGVVAPGNSIGALTVAGNYAGTGGSLEVEAVLGGDAVPADRLVLDGGAASGVTPVVVKPQGGVGGLTLRGIPVVVAQGGATTAPGAFRLAQPLVAGAYEYQLLRGAGDGAAAQAQDWYLRTSRVERDKAGRIVKVVPFYRPEVALYAGTPMLMRMTGTEMLGSYRERAGQTGAVSPEAGATAARGGWARTFGRRFERSAGGEAAPSFDGHLAGAQLGADLYARSSATRHTDAFGVFGGYATVRGDVHGLARGEIQAVGTSTLRATQLGAYWTHTGPGGWYIDTVLAGTRYRQQTKSSAQVGAVSRGWGMTASVEAGYPWQLNLRWRIEPQAQVVYQQLGIANGADRVSTVSYKTPDALTARLGTRLSGQYAYGKAQLRPFMGVSLLHDFTGADTVTFAGAHGVRASRQNTAVDLKAGVDTQLGKSVGLWGQVGYGKSVGSGDGSDRGWSANLGLRVAY
>NZ_AP014582.1|WP_003807750.1|476543_476675_+|entericidin-A/B-family-lipoprotein
MNNRIRAALLAAITLVALAGCNTMSGAGKDIERGGEKIQEKAQ
>NZ_AP014582.1|WP_080772873.1|469537_476266_+|autotransporter-associated-beta-strand-repeat-containing-protein
MPQRSQPFNSCTGHSGVRGHGVAPTVLVLALGFHGTAAWANCQTAGSAVTCDASSPNPYTGTVGSGASSGNLTITVGPGARIESGNAHAISVGTGNTISLDGNAQVSNSVTTGGPGNYNAGLNTIEFEHSNTLMIGADARVAAEGTDPAAHAIAFTGRSNAVTNYGTVSSASGAAIWNQFEDDYVNNTIHNYGVIETTANGGDAVVIGSATGNGASGRGMTLYNYAGGRIVGNVVLGEGDDTVRLEAGSTLTGSLDGGAAGTDVLYLEGTSGSGELTQDISNFNEINKIVNGSTWTLAGSLGANSSGKATVVNAYNGELIVTGDNSAATAGSMMTVWAGARLQVNTTSAMAAIQSNGSGVAAFSQQTDGTYAGVLSGSGNFAKEGAGSLTLTGVNTYTGTLQLKEGKVIVSAAENLGGANSMLEFDGGTLNTTSDMTSVRRASIAAGGGTFEVAGGTTLNWTGRVTGNGTLVKEGAGTLALSGFNAHGGTVVNAGTVQISSDYGLGNGALTLNNSRLASTADIYTEAAATVNGNGTFDTANGTTLQWMGDIGGAGALVKTGAGTLLLGGDSLYAGGTVVNAGTVQVFKDASLGGGALTLNNASLASLGSFSTARAATLTGNGTFDTATGTTLGWTGDIGGAGALVKTGQGTLVLGGDNQYGGGTTVNAGAVQVARDANLGAAAGTVALNDARLASTGTFSTARAATLTGNGTFDTATGTTLEWTGDIGGAGALVKTGQGTLVLGGDNQYGGGTTVNAGAVQVARDANLGVAAGTVALNGGTLAASASFSSARGVTIGAGNGAMSVASGASLDWQGLIGGTGALAKEGAGTLVLGNDNQYAGGTVVNAGTVQVARDANLGAAAGAVTLDGGTLAASAGFTSARGVTIGAGNGAMSVASGASLDWQGLIGGTGALIKEGAGTLVLGNDNQYGGGTTVNGGTVQVARDANLGAAAGAVTLDGGTLAASAGFTSARGVTIGAGNGAMSVASGASLDWQGLIGGTGALIKEGAGTLVLGNDNQYAAGTVVNAGTVQVARDANLGAAAGTVALNDARLASTGTFSTARAATLTGNGTFDTATGTTLGWSGDIGGAGALVKTGQGTLVLGGDNQYAGGTTVNAGAVQVARDANLGAAAGAVALNDARLASTGTFSTARAATLTGNGTFDTADGTALGWTGDIGGAGALVKTGQGTLVLGGDNQYGGGTTVNAGTVQVARDANLGAAAGAVTLDGGTLAASAGFTSARGVTIGAGNGAMSVASGASLDWQGLIGGTGALAKEGAGTLVLGNDNQYAGGTVVNAGTVQVARDANLGAAAGAVTLDGGTLAASAGFTSARGVTIGAGNGAMSVASGASLDWQGLIGGTGALIKEGAGTLVLGNDNQYGGGTTVNGGTVQVARDANLGAAAGTVALNDARLASTGTFSTARAATLTGNGTFDTATGTTLGWSGDIGGAGALVKTGQGTLVLGGDNQYAGGTTVNAGAVQVARDANLGAAAGAVALNDARLASTGTFSTARAATLTGNGTFDTADGTTLGWTGDIGGAGALVKTGQGTLVLDGDNQYGGGTTVNAGTVQVSRDANLGAAAGAVALNDARLASTGTFSTARAATLTGNGTFDTADGTALGWTGDIGGAGALVKEGLGTLVLDGDNQYGGGTTVNAGTVQVARDANLGAAGGAVRLQGATLASTGSFASARALTLGAAGGTFATLGATTLGWDAAIDGAGGLTKTGAGDLVLSQANTYAGPTLIKEGRLAVNGSIASPVTIDPGGVLGGTGRVLGAVANSGTVAPGNSIGTLTIVGNYAGTGGRLEMEAQLGGDASPADRLVIDGGAATGRTDVVVINQGGLGGQTDQGIPLVVARNGATTTADAFSLASPVAAGAYEYKLLRGTPDGTAANAQNWYLRSGLLVPPAEVPGGGPGGAPEPEFIPFYRPEVALYAGAPMLMRAVGLQALGTYHERTGEQGLMTRDDPDPVRRGAWTRAFGRTFERSGSGDVDPRFDGHVAGLQAGVDLYARRSDQGHADLAGVFGGYANARGHMDGFARGETGAYAGKPDLNAYYIGGYWTHIGPSGWYVDAVLAGTRYEQKAKSSNDLRTEAKGWGVTASVEAGYPVPIGEKWHIEPQAQLVYQRLTVSNGEDDVSSVSYRTPDSVTARLGARLSGQYAYNTTQLRPFMEVSLLRDFAGTDTVTFSGIDRIDSRYQATAVDLTAGLVAQVRKDVGLWGQVGYGKSIGGGDGSDRGWAASLGLRIEY
>NZ_AP014582.1|WP_015064629.1|469041_469224_+|DUF3596-domain-containing-protein
MSGKFEGVRPASESSIEISFVYQGRICVRRLRMKPTAANLKRAAEQRAAIVEAIARGEQA
>NZ_AP014582.1|WP_033451560.1|468136_469045_+|LysR-family-transcriptional-regulator
MLRIEDLQLAAALAQAPSLSAAARALNVTPPALSMRLRKLEAGLGLALAVRSARRLSLTPEGERLAREAAALLAQLQALPESLRRDDSRLTGTLRVAAPFGYGRRHIAPVLARLAQRHPELRVQLDLRETPWPDHQDADAVVHIGAVRDSSWVTRRLADNERWLCASPQYLQDHGMPREPRDLLHHRCICIRENDEDASLWRFRRADAGAAGRKAAETVRIAPAYVSNDGNVARTWAEQGLGLVVRSQWDAEGAVARGALVRVMPQWQLDSAPVMLLVPGRKGRSARVKALLECFDEQAGHA
>NZ_AP014582.1|WP_003819124.1|467385_468045_-|HAD-IA-family-hydrolase
MSIATPTGYPRAVLFDLLTGLLDSWTAWNAAAGSEPAGRAWRAEYLRLAYGCGRYVPYGQLVRDAARATGLPDGAPAALEANWHELPVWDDARSLLRALRPHCKLAVVTNCSRDLGHQAAGLLGVDWDAVVTAEEAGFYKPDPRPYRMALQALQVPAGDAAFVAGSGHDLFGTAAVGLRTCWHNRLGLARPQGAPEPELQSATLAAALPWLQAFRPAVR
>NZ_AP014582.1|WP_003807744.1|466213_467359_-|DSD1-family-PLP-dependent-enzyme
MTTTHAHPLDTLDTPAAIVDVARMQHNIARMQDRMNGLGVSLRPHVKTSKCTPVALAQLAAGARGVTVSTLKEAEQFFAAGIADILYAVGMAEHRLPAALALRRRGCDLKIITDNAESARTIADFGRAHDEVFEVWIEIDTDGHRSGIKPEEAALLAVGAALHEGGMRLGGVMTHAGSSYDLDTPEALAAMAEQERAGCVRAAERLRAAGLPCPVVSVGSTPTALSAAQLQGVTEVRAGVYVFFDLVMHNIGVCRVDELALSVLATVIGHQADKGWVIVDAGWMAMSRDRGTQKQKQDFGYGQVCTADGAPLAGYTLIGANQEHGIMAGGPAGEDVTTRFPVGMRLRILPNHACATGAQFPQYHALEADGGLQAWERAHGW
>NZ_AP014582.1|WP_003807743.1|465737_466073_-|YegP-family-protein
MSGYFVLKASGTQYMFNLHAGNHEIILTSERYTSKASAQDGIASVQKNAPDDARYQRLTAKDGSPYFSLTATNGQSIGRSEMYKTTQARDNGIASVKSNAPGAPTKDQTQA
>NZ_AP014582.1|WP_003807742.1|464801_465662_+|exported-protein
MIPRNAKLAAGAGVLFVLILMLAFSSWFQVDQGERGVVLRNGKLVRVSEPGLDFKTPFIDSVSTVSVRDHTFIFENLEAYSYDQQPATLRVSVTYRVPAEHVAELYAEYGTISNLQMRVLERKTPDAVKNVFGRYTAVRAIQERQKLGVDVNAAVLSAMDGAPVQIVGVQVEEVGFSKAYEHSIEQRMLAQVQIETTRQQKETAMITAEIQVVKAKAEADARRQQFTAEADGIRLRGEAEAASIRAKAEALAANTNLVSLNAVEKWDGVLPATQVPGAALPFIGIK
>NZ_AP014582.1|WP_003807753.1|485080_486058_+|tripartite-tricarboxylate-transporter-substrate-binding-protein
MYRIVSALAVSVTCLAGMGAAQADQGAAAYPDKPIKIVIPYSAGGGTDQFMRIVSERASRVLGQPITILNKPGGSTVIGVNAVIGAAPDGYTLLVSTNTSYTLIPYVMSPPPYAPEKSLDYVATLGQTSMVLTANKTMPSDLKTVLDSARQSPGRYTYATYGVGSSTHLAGEVFMNDTGVEFRHIPYKGVEAVTALAGNQVDLMIDGINAAGTMLDAGKTQALVVLQRTRSQFLPDTPTLVEAGYPEAAENVISYVMAAPKGTPAAVIDKLQKSFAEALRDPGVLAQAKAMRTEAAFKGPAQTQAFVDSQSALFKDIVAKKNIKF
>NZ_AP014582.1|WP_033451607.1|486092_487646_+|acyl--CoA-ligase
MQPPGQTWWDIIEAHARRFPERDALAHGDGAITYGELVARVRRCAAGLSARGIGAGDCVALLAPPTPDAMVCLLAAARLGALWVGLNPRYQAREMAYVIGHAQPKLVLSVREFEARRYADDLEAALATLAPQARRPELLYYDSQASCDEAMLHALCDAPDAACPAPFDDAAQPCMLVYTSGTTGNPKGVLLSQTALIYRSTVQARTFATRSHPVVINFAPINHIGGMHFRGLSQILADGTIIYQERYRPAEVMGLIEKHRVNMLMLGSTMLQMLIREPSFDMSIMRGMEWFIFSGAAIPMPILQRVKEHCPRIGSTYGLTESCGSVSYIVASDSLEAAAYTVGRAIPEGQLRVADEQGQPLPAGTQGELQVRGQYCMNGYLRDAAATAGAFTRDGWLKTGDMAQREDDGNFRLVGRIKEMYKSGGYNVYPREIEVVLEQHPNVLMSAVIAVDDELYQQVGHAHLILRPDTEVSEPELVQWCRERMANYKVPKRIFVRNSLPMLSIGKVDKIALRQQH
>NZ_AP014582.1|WP_003807755.1|487653_488394_+|IclR-family-transcriptional-regulator
MSNPLNRYHHILHAIAGRPGGLSLADLAAATGLPRSTTHRMATTLREIDYLGQDDASGNFVLGDGLIGLMRSSLAQDSKLALFDPALNFVVGRLEETAFCARLWNDEVDLVQAVTPTRKDQLYIYPGVGGRPLDKCSSSKAILAYLDPARIQALLEPLASSTPGLRVDTLMQELDQVHRQGFAICDGEIDEGVLSVACPVMSGPARGLYSIGVVGPAARLKSHDLQEIVEVLHSAADLAAAELLNS
>NZ_AP014582.1|WP_010925816.1|488417_489182_+|enoyl-CoA-hydratase/isomerase-family-protein
MKEIISLEKTGAVATVTIDRGGKRNALSQEMVLRLTDIALQLQQDTSVACIVLSGNQNEFSAGIDLGDATRWSLDDKTQLERRAIALRGTRLCKAWEDLPQITIAAVEGMNVGGGIALTLACDWRVMGKSAFLFVPEVQIGIPLGWQTIPRLVNLVGPARAKQIVLLGEKMSADTALEWGVADFVVADGAACAHAQDLAARIGKMPELAVRMSKQSINAYANALNHLGSHMDVDQAMLCGQTQDAVAVRDRYAR
>NZ_AP014582.1|WP_003807759.1|489226_489562_+|carboxymuconolactone-decarboxylase-family-protein
MLDWNQYRSELMTRIGEIAKASPETVKGYQQLSAAGKQTNQLDAKTRELIALAVAVTTRCDGCIAVHAKAATDNGATKGEIAEALGVAVALNAGAALVYSARVMDAVDAAQ
>NZ_AP014582.1|WP_033451571.1|489615_490596_+|tripartite-tricarboxylate-transporter-substrate-binding-protein
MSRLARLLLAGCCALGAAAPAGAGNWPAGPVTFIVPFPAGGSMDTFSRPIAGQLSKELGVPVVVSNRSGAGGGVGIAAIARAAPDGYTIGMSSVGNMAINPHIYPDLPYSPLKDFTPIGLAGRFVNVLVVNSKIPARNVQELIELDRKKPGNITFASAGNGSTNHLSGELLKQLTHTSFLHVPYRGSGPALADVVAGNVAFMFDTLNTSMPLIESGALRALAVTSAERSPFLPDVPTMNEAGVAGYAKSGEDLWWAIIAPQGVPADVRDKLNAALNKALGSPALQAQVRAQRVETLTSTPDALQTILRDDYNRWGGIVREAGVKLD
>NZ_AP014582.1|WP_050484259.1|490695_491250_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MPCLVRFEESSMFDALLLTQNDDRAIVAQRVQLDEARLPDGDVLVDIAWSTVNYKDALAITGRIPIVRQFPMVPGIDFAGTVLESHDSRHRAGDAVLLDGWGLGQAHWGGLARKARVKADWLVPMPGGMDARRAEAWGRLASELPAEITDANTRAITLDEVVDLAPRLLAGQVRGRVVVDVGAG
>NZ_AP014582.1|WP_003807765.1|491341_492595_+|CoA-transferase
MQSFYQEPAVAADLKEAPHPPKALSGLRVLDIATFLAAPFCGTIMADFGADVIKIEQPKGGDSLRKFGTPSPCGDTYMWMSEARNKRFVTLDLRTPEGAALFKELVRESDVVLENFRPGTLEKWGLGYDVLSELNPGLILLRVSAYGQDGPKREEPGFARIAHAFGGLAHLAGEPDGPPVVPGSTSLADYISGLWGAIGVLTALQARNHTGLGQVVDIGLYESVFRLLDEIAPVYAATGFVRRRLGADVPNVAPHSHYQTRCGQWVAIACSNDRMFERLASAMGKPELAGDARFATAAARAENRPAINAQVAAWSARFDLQALLDLCRDEGVPCSKVYSIEDIFQDEQYRARGNLMEVDDPRIGKTVLPAPVPRLSGTPARFLRAGGALGQDNAGVFEELLGVCGERLAALRQAGVV
>NZ_AP014582.1|WP_015064624.1|492572_493535_-|LysR-family-transcriptional-regulator
MGKEKSRPLPNINLKLLHTFMLVAEHCSFRQAAELSHRSQAAVTGQIKQLEAQLGVDLFHRTTRQVRLTAEGTQLLESARRAVHEMENGLRQIQETVDLKRGRIFLSCSTTVSSTRLAPILAAFERDYPGVEVFVRELTSGDMFETVRREEADFGIGPIMELPEFDFEPILTENLYAVVPRNLFPDTAEQITLARLASMPLLLLNPGTALRALIDDTARSRGLTINTKFQFSQAQTLISMATAGLGAAVLPAMVLPAKPHKDVQVLPIASPRMTRDVAIVRLRHRKLTPAAARLAQLVRDLIHGPSGRRTARATTRRPPA
>NZ_AP014582.1|WP_010925819.1|493687_494164_+|MaoC-family-dehydratase
MLLARGRLLEDFKTGDQYAHWPGRTITEADNIQFSLLTMNRHPAHCDHHYASQTEFGKPLVNSGLTLAIVLGMSVDDISANAVANLGWQEIELLAPVHPGDTVYARSQVLSVRESKSRPGQGVVTVRTEGVRADGVVFMRFVRSCLVPSRASLAGARQ

Crispr_ID: NZ_AP014582_2

• CRISPR_ID: NZ_AP014582_2
• CRISPR_location: 1001861-1001945
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_AP014582_2

Consensus_repeat	Method
GGTGCCTGTCCCCGCGGGGACAG	CRISPRCasFinder

spacers of NZ_AP014582_2

>2.1|1001884|39|NZ_AP014582|CRISPRCasFinder
ATACCGTCTTGGCAGGCTAGTGTTCATGGCGTATGACAG

CRISPR arrays and Neighbor proteins around NZ_AP014582_2

CRISPR arrays

The CRISPR arrays of NZ_AP014582_2

>merge|NZ_AP014582|2|1001861-1001945|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAGATACCGTCTTGGCAGGCTAGTGTTCATGGCGTATGACAGTGTGCCTGTCCCCGCGGGGACAG

>NZ_AP014582|2|2|1001861-1001945|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAG	ATACCGTCTTGGCAGGCTAGTGTTCATGGCGTATGACAG
TGTGCCTGTCCCCGCGGGGACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014582.1|WP_003808577.1|998212_998833_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	unknown	unknown	gnl|CDD|223813
NZ_AP014582.1|WP_003808574.1|997682_998192_-|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl|CDD|234674
NZ_AP014582.1|WP_003808599.1|1009125_1009590_+|transcription-antitermination-factor-NusB	unknown	unknown	gnl|CDD|234686
NZ_AP014582.1|WP_003808580.1|1000154_1001753_-|CYTH-and-CHAD-domain-containing-protein	unknown	unknown	gnl|CDD|143624
NZ_AP014582.1|WP_003808589.1|1003696_1004467_-|phosphonate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213223
NZ_AP014582.1|WP_172452875.1|1002809_1003679_-|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl|CDD|273441
NZ_AP014582.1|WP_003808568.1|996162_997380_-|benzoate/H(+)-symporter-BenE-family-transporter	unknown	unknown	gnl|CDD|281578
NZ_AP014582.1|WP_003808594.1|1005625_1006453_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_AP014582.1|WP_003808566.1|993252_995772_+|AsmA-family-protein	unknown	unknown	gnl|CDD|236772
NZ_AP014582.1|WP_003808570.1|997376_997628_-|YfhL-family-4Fe-4S-dicluster-ferredoxin	unknown	unknown	gnl|CDD|319871
NZ_AP014582.1|WP_003808584.1|1001991_1002813_-|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl|CDD|273441
NZ_AP014582.1|WP_003808598.1|1008590_1009118_+|6,7-dimethyl-8-ribityllumazine-synthase	unknown	unknown	gnl|CDD|234606
NZ_AP014582.1|WP_003808562.1|991982_992489_-|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176905
NZ_AP014582.1|WP_003808567.1|995768_996155_+|MOSC-N-terminal-beta-barrel-domain-containing-protein	unknown	unknown	gnl|CDD|281474
NZ_AP014582.1|WP_033455490.1|998908_1000108_+|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl|CDD|236686
NZ_AP014582.1|WP_003808597.1|1007401_1008577_+|3,4-dihydroxy-2-butanone-4-phosphate-synthase	unknown	unknown	gnl|CDD|237587
NZ_AP014582.1|WP_010927717.1|1006458_1007256_-|HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|273651
NZ_AP014582.1|WP_003808563.1|992485_992824_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|223713
NZ_AP014582.1|WP_003808600.1|1009629_1010646_+|thiamine-phosphate-kinase	unknown	unknown	gnl|CDD|235583
NZ_AP014582.1|WP_003808591.1|1004469_1005477_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270291

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_AP014582.1|WP_003808563.1|992485_992824_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	3.6e-19	64.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP014582.1|WP_003808577.1|998212_998833_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	gnl|CDD|223813	COG0742, COG0742, N6-adenine-specific methylase [DNA replication, recombination, and repair].	1.53382e-57
NZ_AP014582.1|WP_003808574.1|997682_998192_-|pantetheine-phosphate-adenylyltransferase	gnl|CDD|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	3.03384e-101
NZ_AP014582.1|WP_003808599.1|1009125_1009590_+|transcription-antitermination-factor-NusB	gnl|CDD|234686	PRK00202, nusB, transcription antitermination factor NusB.	1.22823e-51
NZ_AP014582.1|WP_003808580.1|1000154_1001753_-|CYTH-and-CHAD-domain-containing-protein	gnl|CDD|143624	cd07756, CYTH-like_Pase_CHAD, Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain. This subgroup belongs to the CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) superfamily. Members of this superfamily hydrolyze triphosphate-containing substrates, require metal cations as cofactors, and have a unique active site located at the center of an eight-stranded antiparallel beta barrel tunnel (the triphosphate tunnel). A number of proteins in this subgroup also contain a C-terminal CHAD (Conserved Histidine Alpha-helical Domain) domain which may participate in metal chelation or act as a phosphor-acceptor. The name CYTH originated from the gene designation for bacterial class IV adenylyl cyclases (CyaB) and from thiamine triphosphatase. Class IV adenylate cyclases catalyze the conversion of ATP to 3',5'-cyclic AMP (cAMP) and PPi. Thiamine triphosphatase is a soluble cytosolic enzyme which converts thiamine triphosphate to thiamine diphosphate. This domain superfamily also contains RNA triphosphatases, membrane-associated polyphosphate polymerases, tripolyphosphatases, nucleoside triphosphatases, nucleoside tetraphosphatases and other proteins with unknown functions. Proteins of this subgroup have not been characterized.	5.26778e-56
NZ_AP014582.1|WP_003808589.1|1003696_1004467_-|phosphonate-ABC-transporter-ATP-binding-protein	gnl|CDD|213223	cd03256, ABC_PhnC_transporter, ATP-binding cassette domain of the binding protein-dependent phosphonate transport system. Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	6.7095e-115
NZ_AP014582.1|WP_172452875.1|1002809_1003679_-|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl|CDD|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	3.46758e-90
NZ_AP014582.1|WP_003808568.1|996162_997380_-|benzoate/H(+)-symporter-BenE-family-transporter	gnl|CDD|281578	pfam03594, BenE, Benzoate membrane transport protein.	3.72852e-112
NZ_AP014582.1|WP_003808594.1|1005625_1006453_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	9.15813e-52
NZ_AP014582.1|WP_003808566.1|993252_995772_+|AsmA-family-protein	gnl|CDD|236772	PRK10833, PRK10833, putative assembly protein; Provisional.	2.80816e-30
NZ_AP014582.1|WP_003808570.1|997376_997628_-|YfhL-family-4Fe-4S-dicluster-ferredoxin	gnl|CDD|319871	cd10549, MtMvhB_like, Uncharacterized polyferredoxin-like protein. This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.	1.53234e-06
NZ_AP014582.1|WP_003808584.1|1001991_1002813_-|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl|CDD|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	1.08607e-97
NZ_AP014582.1|WP_003808598.1|1008590_1009118_+|6,7-dimethyl-8-ribityllumazine-synthase	gnl|CDD|234606	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional.	4.04555e-65
NZ_AP014582.1|WP_003808562.1|991982_992489_-|SRPBCC-family-protein	gnl|CDD|176905	cd08896, SRPBCC_CalC_Aha1-like_3, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	7.32648e-83
NZ_AP014582.1|WP_003808567.1|995768_996155_+|MOSC-N-terminal-beta-barrel-domain-containing-protein	gnl|CDD|281474	pfam03476, MOSC_N, MOSC N-terminal beta barrel domain. This domain is found to the N-terminus of pfam03473. The function of this domain is unknown, however it is predicted to adopt a beta barrel fold.	7.15282e-08
NZ_AP014582.1|WP_033455490.1|998908_1000108_+|signal-recognition-particle-docking-protein-FtsY	gnl|CDD|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	5.35372e-175
NZ_AP014582.1|WP_003808597.1|1007401_1008577_+|3,4-dihydroxy-2-butanone-4-phosphate-synthase	gnl|CDD|237587	PRK14019, PRK14019, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II.	0
NZ_AP014582.1|WP_010927717.1|1006458_1007256_-|HAD-IIB-family-hydrolase	gnl|CDD|273651	TIGR01484, Putative_mannosyl-3-phosphoglycerate_phosphatase, HAD-superfamily hydrolase, subfamily IIB. This subfamily falls within the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The Class II subfamilies are characterized by a domain that is located between the second and third conserved catalytic motifs of the superfamily domain. The IIB subfamily is distinguished from the IIA subfamily (TIGR01460) by homology and the predicted secondary structure of this domain by PSI-PRED. The IIB subfamily's Class II domain has the following predicted structure: Helix-Sheet-Sheet-(Helix or Sheet)-Helix-Sheet-(variable)-Helix-Sheet-Sheet. The IIB subfamily consists of Trehalose-6-phosphatase (TIGR00685), plant and cyanobacterial Sucrose-phosphatase and a closely related group of bacterial and archaeal sequences, eukaryotic phosphomannomutase (pfam03332), a large subfamily ("Cof-like hydrolases", TIGR00099) containing many closely related bacterial sequences, a hypothetical equivalog containing the E. coli YedP protein, as well as two small clusters containing OMNI|TC0379 and OMNI|SA2196 whose relationship to the other groups is unclear. [Unknown function, Enzymes of unknown specificity].	7.51884e-15
NZ_AP014582.1|WP_003808563.1|992485_992824_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|223713	COG0640, ArsR, Predicted transcriptional regulators [Transcription].	2.51065e-15
NZ_AP014582.1|WP_003808600.1|1009629_1010646_+|thiamine-phosphate-kinase	gnl|CDD|235583	PRK05731, PRK05731, thiamine monophosphate kinase; Provisional.	1.95453e-132
NZ_AP014582.1|WP_003808591.1|1004469_1005477_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	gnl|CDD|270291	cd13573, PBP2_PnhD_3, Substrate binding domain of uncharacterized ABC-type phosphonate-like transporter; contains the type 2 periplasmic binding fold. This subfamily includes putative periplasmic binding component of an ABC transport system similar to alkylphosphonate binding domain PnhD. These domains are found in PnhD-like proteins that are predicted to function as initial receptors in hypophosphite, phosphonate, or phosphate ABC transport in archaea and eubacteria. They belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.92107e-151

Protein sequences

>NZ_AP014582.1|WP_003808580.1|1000154_1001753_-|CYTH-and-CHAD-domain-containing-protein
MSEQELKLHVPAAARAAVQQQIQQRQAARIRLHAMYFDTPGRELARARIAIRLRQEGRDWVQTLKMPGANAISRVEINHPRPGPVLDLSVYAGTEAQAALTAIKGELGLRYETDVQRLFCKVRGRHGTVELAYDTGVLRAGALELPISELEFELVSGRPAAIFAMARSWLQRHGLVLDARSKSERGDALAQLAHDLAAAPGEADDAARATRDQQAVAGFWAPRNAGAVKLDESMTPMQAMAAVAAECVDHIARNAAVLAEVDTLGVYRAGTPEHVHQLRVGVRRLRSAWRLFDGWVADPSETLAQGARTHFSAFGMARDQDVLADTIMPLLARAGMPALPAEAAPSNDNAQSLAADRAFQGWLLELLAWSLDVPPPPAPAATAEAAPASPTIIPLAPPAEAAPPALRKRLTGRLRRWHLKVIDEGLRFGALELEARHELRKRVKRLRYGLSFAESLLPAARLRTYRKQLARVQDLLGEINDLAVARDYYQAALQAHPQAWFAVGWIGARLDGLTPQAQEAFDQLARAKPFWK
>NZ_AP014582.1|WP_033455490.1|998908_1000108_+|signal-recognition-particle-docking-protein-FtsY
MFSFFKKKSPPPAAPAQPAPPPEAVDAGSAAPAQPQPAEPQPAPMPAPQPEPQPEPQPQQPPEPAPPAMASPPVAEPQPSVAEPQPPVAAAPEAPRKASWLSRLKQGLSRTGQNIGGLFVGVKVDENLFEELESALIMADAGIEATEKLLAALRARVKKERIDDPAQVKTALRQLLADHLRPLERSFDLGRAQPLVVMIAGVNGAGKTTSIGKLAHTFQRQGASVLLAAGDTFRAAAREQLVEWGSRNNVTVISQDGGDPAAVAFDSVNAGRARNVGVVMVDTAGRLPTQLHLMEELKKIRRVIGKAEASAPHEVLLVVDGNTGQNALAQIRAFDAAITLTGLVVTKLDGTAKGGTLAAVAAGSQGVRPIPVYWIGVGEGLEDLQPFVADEFAAALLAD
>NZ_AP014582.1|WP_003808577.1|998212_998833_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD
MKPSRPGSKPIRIVGGLYRRTLIPVADAPGLRPTPDRVRETLFNWLNHLWGGEFADKRVLDLFAGSGALGFEAASRGAGQVQMVERDRGAAAALRTLRDKLQAGAVRIHAGDAMQVIERMDASRFDLVLLDPPFGQGWLERLWPLLPAVLAEDGLVYVESETAPAPPAGFELLREGKAGAVHYRLFQFAAMRKSMNNPALEDGASH
>NZ_AP014582.1|WP_003808574.1|997682_998192_-|pantetheine-phosphate-adenylyltransferase
MIIAVYPGTFDPLTRGHEDLVRRAATLFDKVVVGIAHSRNKKPFFTIEERVDIAREVLGHYPNVEVHSFGGLLKDFVRDQNGRVIIRGLRAVSDFEYEFQMAGMNRHLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVERWLQAKAKERREQSAQGGA
>NZ_AP014582.1|WP_003808570.1|997376_997628_-|YfhL-family-4Fe-4S-dicluster-ferredoxin
MALKITEECINCDVCEPQCPNEAISMGADYYVIDPDRCTECVGHHDEPQCKVVCPVECIELHPQWQEGQEQLMAKYRRLTGAA
>NZ_AP014582.1|WP_003808568.1|996162_997380_-|benzoate/H(+)-symporter-BenE-family-transporter
MNGADSASSPLAARRPVTGALSLSAIVAGLVAVLVSFGGTAVLMVQAGHAAGLDAARIGSWLGSICLALGVGGALISLRSRMPVVFAWSTPGAALLVTGLVGVPFDQAVGAFVLAAALTLACGVFGWIDPIVRRIPAELAAAMLAGVLLNFGMGIFGSIAAQPVLVLSMCAAYLLGRRWAPRFAVLAVLVVGLAAASSLDLLRLGHVQWAWTEFVWTTPSFTWQAAISLGIPLFVVAMASQNLPGLAILQAAGYRPPASRLVGLTGLAGLLAAPFGAHSVTLGAIIAALCAGPEAHADPGRRYVAAATYGLTYVLLSVAAGAVAVFFQALPGALIAALAGLALLGAIMGGMTTAMADPQRREAALVTLLATASGISFWGIGSAFWGLAAGLATHGALAWRRARSA
>NZ_AP014582.1|WP_003808567.1|995768_996155_+|MOSC-N-terminal-beta-barrel-domain-containing-protein
MSTTAYQPIAECGATTQSEAAAYQKRWLVANDAGQWLNRDLCPRLAEVSVELRMGYLVLKAPGMLRLDIPLDVIEDDDSVRYQMLVGEQTVDVVDEGELAAAWISNHAGVPCRILKVHPDMAEVRWPS
>NZ_AP014582.1|WP_003808566.1|993252_995772_+|AsmA-family-protein
MKTWFKRIVIGLVVLVVVAVVGLAIFLLTFDPNAYKYKLEEAVQARYERTLNIEGEIELSLFPRIGLAVQGVSLSEPNSPDVFASIDSMRLAVAVWPLLSNSLVVDHVTINGFKARVIRGKDGHFNFENLVGGSVQSTDVPGNAAEATAGAITGTAQAIVNGTVSTPKSMQIDIAGLDLKDGEIQLQDAMSGMAVAITKLNAATGRVTYNQPFDVSLSARVEGGNPRLDAGLTGQAQLTLDPLAKRYAAQRLDLRMEGRLPGAQAKSLAARGNVAFNGMTSSLDVAGLEILFQGDIVDTATKLTNVEASVAMPKLAVDPHKTELQIDKLAVRAKGAMPGGPFELAVDAPALNISPTNASGDALSGRVRTQELDASFGLNGISGNAGELDIKEAKLDSTLKQGERVVKSAFASPVTLNLLQRSIGLSALKGDVNITDPGLPKGSLQIPVIGSVNANLLKDQANARINAVLEGGKFDLSADIVALSAVPRVTFALAVDTLDLDKLAPPAGASAPPKPAGDGKQDESKPPAKPQPAPAPAAADDSINLSGLVGPTASGTIKIGQLVMRGLKAEQVAANIKLEKGKLDISTLTAALYGGKLGGVMSVDAVNGNQLVAKMSLAGIAIQPLLSDLAGKDTLSGTGSLAFDLKTAGANTYAMKSGLAGTMQVRLRDGAIKGINVAQTLRELKAMFRGEAHDPTVQDDQTRQTDFTSLESDLVFNKGVATVKRLDMAAPLLRVNQGNPANIDFVRSELDFVARVRVVNTSTGQDGKDLAELRNLTIPLLITGPFDKPVYTLQWREVAGEALKRGLEKQLKEALTGGEGASGSPAKNIDKALKGILGK
>NZ_AP014582.1|WP_003808563.1|992485_992824_-|helix-turn-helix-transcriptional-regulator
MPNQAAQLSQVFQALSDPTRRAVLERLCQGSAAMSELARPFNMALPSFSQHLDVLERCGLVRSRKSGRVRIYTLAPQPLGMAEHWMTRQRAIWERRLDQLDLYLQDLKEQKR
>NZ_AP014582.1|WP_003808562.1|991982_992489_-|SRPBCC-family-protein
MTRQHSTQPDPKLDLVLERTIDVPPALVWQAWTQPEHIKHWLTPAPWQTVRCDVDLRPGGRFRFVMRSPEGEEHTHDCCYLEIVEGSRLVWTNALLPGFRPAGGGGDVPAFTAVIRIEPHDQGTRYTATAMHGTQAGCRQHSDMGFHDGWGAALDQLVAHARNMQQAS
>NZ_AP014582.1|WP_003808584.1|1001991_1002813_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MNTSVTSLEPGHPRTWQRYSGGQKALRFMLYLLLVAAIVQAVRSVEVIPEFLYDAPEQMADLLRRMWPIDWSYYPEGVHAALVETLHIATLGTILSVGMAVPVGLLAANNLTPSRTINMLARLILVSSRSVNSLVWALLFIAIFGPGALAGTLAIAFRSIGFVGKLVGEAIEEAQRGPIEALTATGASKAAVLWYGYWPQIRPSFWSIVLLRWDINVRESAVLGLVGAGGIGMALDTALNLFQWDRVALVLAAIFIVVVAAEIVITQARKRIL
>NZ_AP014582.1|WP_172452875.1|1002809_1003679_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MARRPFSLSWRAKTGVLLVVLYTFYAAAQLDFSWARFETGLGHAATFLARMFPPNFEKPDTLWKGIAESLEIAVLASVLGILLSLPIGLLGARNLMPAWASWPARALVALCRALHPVIVAILFVKAVGFGALAGILALTVASIGFIGKLFTEAIEEISLKQVEAVRASGASFGNVIIFGVLPQVFARFVGFATYQFDSNLRNSTMVGIVGAGGIGGTLFSAFQRFDYDFVAAILLTLIAIIMLGEILAGFVRKVFLDNMGFERILQRRFTAARGLGSTTPLARKGEVDE
>NZ_AP014582.1|WP_003808589.1|1003696_1004467_-|phosphonate-ABC-transporter-ATP-binding-protein
MATSLRITGLVKEYRAGKPVLNGIDLDIAGQGLTAIIGPSGTGKSTLLRCINRLIEPTSGEIVLKDAEGTVDLARVRGQSLRRARRRIGMVFQEYNLVERLTVMENLLTGRLGYTSALNAWMRRFDPADIERAFQLLDTVGLAGFADQRADALSGGQRQRVGIARALMQRPQLLLADEPTSSLDPKTSVEIMELLTEQGSVNGIPVLVNIHDVELARRYANRIVGMSGGHVVYDGDGKGLDATMLKTIYGGESWLE
>NZ_AP014582.1|WP_003808591.1|1004469_1005477_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein
MRAKRLLQAAAVTALIFGSYAAQAADAACSNRGDLDNMYCDANKDLVADTPTDKSKLKTPSTLVFTYTPVEDPAVYEDIFKPFTKHLSECTGKRVVFYQVQSNAAEIEAMRSGRLHVGGFSTGPTAFAVNIAGAVPFAVKGYADEFQGYNLIVIVKKDSPYQKLTDLKGKKLAHTAPSSNSGHMAPVALFPKEGLTPDKDYKVIFSGKHDQSVMGVNSGDYDAAAVASDVFKRMAERGQVKEEDFRVIYRSEKFPTSSFAYAHDLEPAFRDKMLKCFYDYRFPDEMKKAFDGADRFYPVTYQKDWAIVREVAESGGEKFNRAAYDRETAKSKGKQ
>NZ_AP014582.1|WP_003808594.1|1005625_1006453_-|IclR-family-transcriptional-regulator
MSAAKSTAKPAAAPGNDGRRSIQSVEVGFPLLAALVDAGRPLTLRDLAGAAGMTSAKAHPYLVSFTRVGLVQQDTVTGQYELGPFALQMGLVSLQRLDPVRVALPEVDKLQSEIGHTLGIAVLGSHGPTMIHITEASYPVHVNMRKGTVMSMLHTATGQVFAAWLPPKVAEHYIAREDGDAAVIASLTPRKTTRANLDAMLADIRVHGMARALGNPLPGVDALSVPVFDHTGGIVLALTSLGPTGLFDASFTGAIARPLLACAQEISRKLGYRGN
>NZ_AP014582.1|WP_010927717.1|1006458_1007256_-|HAD-IIB-family-hydrolase
MQALAAMPAPVAASVRIVLTDIDDTLTTEGRLPAGAYAALERLEQAGIVVVPITGRPAGWCDHIARMWPVRAVVGENGAFYYAYDRSARRMNAHYWADAATRAANRQALQAIRERVLREVPGTAVASDQDYRVADLAIDFCEDVPALPDGAVGRIVEIFHEAGAQAKVSSIHVNGWFGDYDKLTMTRTLFEREFGLNIDSALQHTLFIGDSPNDEPMFKFFPISVGVANIQSQLHRIQHRPAFVAAARGGDGFVEMAERLLANRG
>NZ_AP014582.1|WP_003808597.1|1007401_1008577_+|3,4-dihydroxy-2-butanone-4-phosphate-synthase
MSAQISSLNAGAAPESFGIASVPEIIAELRAGRIVILVDEEDRENEGDLVMAAEFVTPEAINFMVTHGRGLVCLTLTEERCRQLDLPLMASRNGTRYGTNFTQSIEAAEGVETGISAADRARTIQVAVARDAQPSDLVQPGHIFPVRAVPGGVLVRAGHTEAGCDLTAMGGLTPAAVICEILKPDGTMARLPDLVEFAREHKLKIGTIADLIQYRSEHESIIARMGERMMQTPWGDFRCIAYRDDATRSPHLALVHGNIDPERETLVRVHEPASLLDVLDTGASPHSWSVGQALHAIAASPAGVLVLMNCQSSTEHLFGQIANWAGPAERAAAQEGDRFGLRTYGIGAQILRDLNVGRMKLLARPRKMPSMAGFALTITGYDCAPPNLRND
>NZ_AP014582.1|WP_003808598.1|1008590_1009118_+|6,7-dimethyl-8-ribityllumazine-synthase
MNPYILTPDLNGEGLHIGIVRARFNEEIGQAQLQACLEELGKLGVDERDVMVVSVPGALELGVALARMAESYEFDALIALGAVIRGETYHFEVVSNESAAAISRIALETGIPVANGVLTVDTDEQAQARAAGKGADCAQVAVEMANLAAALEPEEDDEDEDDEDEDFDDEEDDGR
>NZ_AP014582.1|WP_003808599.1|1009125_1009590_+|transcription-antitermination-factor-NusB
MQARANARSARRRAREFALQGVYAWLLRGGEGTQDAGEIDAHLRDAEDFSEADAQWFKTLLHGVLREAPVLRERFLPYIDRPLAELSPVEHGILLIGSFELMHHVEVPYKVAINEAVELAKSFGGTDGFKFVNGVLDKLAADVRTAEVQAAPRR
>NZ_AP014582.1|WP_003808600.1|1009629_1010646_+|thiamine-phosphate-kinase
MLAGVALASEFDLIARYFTRPAPDGVLGVGDDCALFPVPPGQQVATSTDLLIEGRHFFPDVDPQALGHKALAVNLSDLAAMGARPVGCLLGLALPGVDEAWLAAFARGFQALADTHACPLIGGDTTRAPQGLLAISVTVFGAVAPGHALRRAAAQPGDDVWVSGELGAADIAYRLLDRQLPADPLRLAATRAALEWPRPRVELGMALAGLARAGIDISDGLLQDLGHILAASGVAAELRYDALPVAAALAGLPAETVRRAALGGGDVYELCFTADPAHRQAIGQAAHGAGAPVSRIGRILAGQGLRVLDADGAPLGELPGGFDHFSDATDQPAPGRRP

Crispr_ID: NZ_AP014582_3

• CRISPR_ID: NZ_AP014582_3
• CRISPR_location: 2172780-2172895
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP014582_3

Consensus_repeat	Method
TTTTTTTGCCGCCGGGCCGCCCCAAGGCAAAAA	CRISPRCasFinder

spacers of NZ_AP014582_3

>3.1|2172813|50|NZ_AP014582|CRISPRCasFinder
AGCCCCCTTGGGGGGCAGCAAGCCCGCACAGCGGGCGCAGCGTGGGGGCC

CRISPR arrays and Neighbor proteins around NZ_AP014582_3

CRISPR arrays

The CRISPR arrays of NZ_AP014582_3

>merge|NZ_AP014582|3|2172780-2172895|CRISPRCasFinder
TTTTTTTGCCGCCGGGCCGCCCCAAGGCAAAAAAGCCCCCTTGGGGGGCAGCAAGCCCGCACAGCGGGCGCAGCGTGGGGGCCTTTTTTTGCCGCCGGGCCGTCCCAAGGCAAAAA

>NZ_AP014582|3|3|2172780-2172895|CRISPRCasFinder
TTTTTTTGCCGCCGGGCCGCCCCAAGGCAAAAA	AGCCCCCTTGGGGGGCAGCAAGCCCGCACAGCGGGCGCAGCGTGGGGGCC
TTTTTTTGCCGCCGGGCCGTCCCAAGGCAAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014582.1|WP_003812734.1|2171160_2171697_+|inorganic-diphosphatase	unknown	unknown	gnl|CDD|179262
NZ_AP014582.1|WP_015064052.1|2180657_2181554_+|type-II-secretion-system-F-family-protein	unknown	unknown	gnl|CDD|224975
NZ_AP014582.1|WP_015064056.1|2175284_2175941_+|hypothetical-protein	unknown	unknown	gnl|CDD|184854
NZ_AP014582.1|WP_003812730.1|2172602_2172734_+|entericidin-A/B-family-lipoprotein	unknown	unknown	gnl|CDD|227797
NZ_AP014582.1|WP_003812713.1|2179801_2180647_+|type-II-secretion-system-F-family-protein	unknown	unknown	gnl|CDD|227300
NZ_AP014582.1|WP_010928268.1|2173351_2174668_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP014582.1|WP_010926375.1|2169536_2171132_+|hypothetical-protein	unknown	unknown	gnl|CDD|273126
NZ_AP014582.1|WP_003812728.1|2173091_2173355_+|membrane-protein	unknown	unknown	unknown
NZ_AP014582.1|WP_015064055.1|2175937_2176783_+|Flp-pilus-assembly-protein-CpaB	unknown	unknown	gnl|CDD|274472
NZ_AP014582.1|WP_010930986.1|2165707_2166427_+|TerC-family-protein	unknown	unknown	gnl|CDD|163429
NZ_AP014582.1|WP_161781140.1|2181553_2182261_+|DUF192-domain-containing-protein	unknown	unknown	gnl|CDD|376876
NZ_AP014582.1|WP_015064053.1|2178188_2179805_+|Flp-pilus-assembly-complex-ATPase-component-TadA	unknown	unknown	gnl|CDD|227297
NZ_AP014582.1|WP_015064057.1|2174664_2175288_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP014582.1|WP_015064054.1|2176779_2178192_+|pilus-assembly-protein-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|333965
NZ_AP014582.1|WP_003812748.1|2163696_2164578_+|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|180194
NZ_AP014582.1|WP_033449580.1|2167522_2168311_+|uroporphyrinogen-III-synthase	unknown	unknown	gnl|CDD|119440
NZ_AP014582.1|WP_015064059.1|2171880_2172576_+|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257
NZ_AP014582.1|WP_003812745.1|2164853_2165549_+|TerC-family-protein	unknown	unknown	gnl|CDD|163429
NZ_AP014582.1|WP_003812737.1|2168348_2169533_+|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|235899
NZ_AP014582.1|WP_003812742.1|2166545_2167490_+|hydroxymethylbilane-synthase	unknown	unknown	gnl|CDD|234612

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP014582.1|WP_003812734.1|2171160_2171697_+|inorganic-diphosphatase	gnl|CDD|179262	PRK01250, PRK01250, inorganic diphosphatase.	2.68623e-113
NZ_AP014582.1|WP_015064052.1|2180657_2181554_+|type-II-secretion-system-F-family-protein	gnl|CDD|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	9.08185e-19
NZ_AP014582.1|WP_003812730.1|2172602_2172734_+|entericidin-A/B-family-lipoprotein	gnl|CDD|227797	COG5510, COG5510, Predicted small secreted protein [Function unknown].	8.70055e-07
NZ_AP014582.1|WP_003812713.1|2179801_2180647_+|type-II-secretion-system-F-family-protein	gnl|CDD|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	3.18806e-34
NZ_AP014582.1|WP_015064053.1|2178188_2179805_+|Flp-pilus-assembly-complex-ATPase-component-TadA	gnl|CDD|227297	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion].	1.81087e-139
NZ_AP014582.1|WP_010926375.1|2169536_2171132_+|hypothetical-protein	gnl|CDD|273126	TIGR00540, TPR_hemY_coli, heme biosynthesis-associated TPR protein. Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General].	5.88418e-71
NZ_AP014582.1|WP_003812748.1|2163696_2164578_+|succinate--CoA-ligase-subunit-alpha	gnl|CDD|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NZ_AP014582.1|WP_010930986.1|2165707_2166427_+|TerC-family-protein	gnl|CDD|163429	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family commonly are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains protein YjbE from Bacillus subtilis. A transport function is proposed.	3.14656e-77
NZ_AP014582.1|WP_161781140.1|2181553_2182261_+|DUF192-domain-containing-protein	gnl|CDD|376876	pfam02643, DUF192, Uncharacterized ACR, COG1430. Two structures have been solved for members of this large (>500 members) family of bacterial proteins present mostly in environmental bacteria and metagenomes (distant homologs are also present in several Plasmodium species). TOPSAN analysis for Structure 3pjy shows that there is much similarity with the other solved structure, Structure 3m7a, solved for UniProt:Q2GA55 (Saro_0823), a homolog of Thermotoga maritima TM1668, UniProt:Q9X1Z6., The homolog in Caulobacter crescentus (CC1388), UniProt:Q9A8G6, is associated with CspD, a cold shock protein (CC1387), UniProt:Q9A8G7. However, the genomic context of UniProt:Q2GA55 is most conserved with a putative xylose isomerase, suggesting a possible role in extracellular sugar processing. Saro_0821, UniProt:Q2GA57, is annotated as an AMP-dependent synthetase and ligase. Structure 3m7a structure corresponds to the C-terminal (27-165) fragment of the YP_496102 (Saro_0823) protein and it is structurally unique, as the best hits from Dali have a Z-score of 3.8 (1nt0, 2j1t, 3kq4) and it is thus a likely candidate for a new fold. Interestingly, many of the top Dali hits are involved in sugar metabolism. There are no obvious active site-like cavities on the protein surface of 3m7a (http://www.topsan.org/Proteins/JCSG/).	9.03894e-09
NZ_AP014582.1|WP_015064054.1|2176779_2178192_+|pilus-assembly-protein-N-terminal-domain-containing-protein	gnl|CDD|333965	pfam00263, Secretin, Bacterial type II and III secretion system protein.	4.23385e-53
NZ_AP014582.1|WP_003812742.1|2166545_2167490_+|hydroxymethylbilane-synthase	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	8.72133e-165
NZ_AP014582.1|WP_015064055.1|2175937_2176783_+|Flp-pilus-assembly-protein-CpaB	gnl|CDD|274472	TIGR03177, pilus_cpaB, Flp pilus assembly protein CpaB. Members of this protein family are the CpaB protein of Flp-type pilus assembly. Similar proteins include the FlgA protein of bacterial flagellum biosynthesis.	3.27424e-49
NZ_AP014582.1|WP_033449580.1|2167522_2168311_+|uroporphyrinogen-III-synthase	gnl|CDD|119440	cd06578, HemD, Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in the human uroporphyrinogen-III synthase gene cause congenital erythropoietic porphyria, a recessive inborn error of metabolism also known as Gunther disease.	1.93222e-44
NZ_AP014582.1|WP_015064059.1|2171880_2172576_+|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	9.66779e-90
NZ_AP014582.1|WP_003812745.1|2164853_2165549_+|TerC-family-protein	gnl|CDD|163429	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family commonly are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains protein YjbE from Bacillus subtilis. A transport function is proposed.	1.70286e-69
NZ_AP014582.1|WP_003812737.1|2168348_2169533_+|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|235899	PRK06975, PRK06975, bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed.	4.52015e-54
NZ_AP014582.1|WP_015064056.1|2175284_2175941_+|hypothetical-protein	gnl|CDD|184854	PRK14852, PRK14852, hypothetical protein; Provisional.	0.00208036

Protein sequences

>NZ_AP014582.1|WP_003812730.1|2172602_2172734_+|entericidin-A/B-family-lipoprotein
MRSKIVLTAFVVFGFVLQGCNTVAGMGKDMSDAGSAITHAAEK
>NZ_AP014582.1|WP_015064059.1|2171880_2172576_+|fumarylacetoacetate-hydrolase-family-protein
MDYVFPPSPPAAVPVAGGNARFPVRRVYCVGRNYAEHAKEMGFTGREDPFFFCKPADAILSVADGATGEMPYPPKTANLHYEMELVVVLGKGGRDLTVEQADECVWGYALGLDMTRRDLQGEAKKQGRPWEVGKAFDLSAPLGPIHPRSAVGTLDKGAIWLDVNGERKQSSDISQMIWNIPESVAYLSGLFELQPGDIIFTGTPEGVGAVVKGDVIVGGVEGLGELRVRIA
>NZ_AP014582.1|WP_003812734.1|2171160_2171697_+|inorganic-diphosphatase
MSLDRVAPGKKLPDDFNVIIEIPMNADPVKYEVDKESGAIFVDRFMLTAMHYPCNYGYIPQTLSEDGDPADVLVLTPFPIQIGAVVRCRAIGVLEMDDESGGDAKLLAVPIEKLYPPYRNIKSYEDLPAEDVSRIQHFFEHYKDLEKGKWVKVKGWKGVDAAHEEIVRSAERYAKGQA
>NZ_AP014582.1|WP_010926375.1|2169536_2171132_+|hypothetical-protein
MRTWFWTLLLAVVAVALAVVLRAHAGNVLLLVWPWRIELSLTLTVLLLVAAFVTLYIGLRLLAWLVAIPDRLRAWRGRRAQERDHELLERGWIGLLEGRFAQAEKDLSKLFDQTKVRSRRVLAALSGARAAHNLGEYERRDRMLESAREQAGEDAGLQEATATVSADMLLDQGRAQQALDLLEPLQDGGARHLHTMRLLLRAETALQHHERVFMLARGLLRRNAIGKAEAEQLIDSAGAARLRAGMAVDQWRPIWKDLKSDERLLPNIALAGAAAFEDAGEASEAARILEAAVAVKFNPALVAAYARCDAAQVPHRLAKAETWLQQRPADTDLLTALGLLCLNGQLWGQAERYLQRSVSRRNDPQAHALLGSLYDRLDRPADAARHWRQATAARVALPVLAADIALPAADTKADPAWLDAEREYVPNMSEYTAPVIADAPPEVEPGAVDYVLDPDARAAGEHEPASAVAPEPVSVPPRTAIDIEDYFDSAPIPAAAIEAPVSSYRAGGDDEQPAKPGGAVSSAGPASGDKA
>NZ_AP014582.1|WP_003812737.1|2168348_2169533_+|uroporphyrinogen-III-C-methyltransferase
MTDNTSATPPGTVPGTPGTAAADEAVASQSRKGKGVNSTLVTALIIVILLAVGLGWAAWLQRKQFVSAGQEVAARLNTLGAELTQSRNDMREALALAQAQSGKVAELEGKVREAQSQYSALQQALQNLNDGASDEMLANDIERLITIASQQLRLAGNVSNAIVALETAQARLARADRPRFASLQQSINGDLDRLRAVGVVDIAAQSARIDRLVALVGRAPLLVPDAAAPGVTAVPQANEAVPASVDPGADLPADAAWWQRWQAEIASWPGRAGSALAHELGDLIRVQRVDQPTALLLSPEQAGQLRSTLRQRLLTAQLSMLMRQPAVWKSELDAVAATLAQYFDGKAPDTVAALALARELGQVEIAVRVPDVADSLNGIAALRAAGFNADGQQD
>NZ_AP014582.1|WP_033449580.1|2167522_2168311_+|uroporphyrinogen-III-synthase
MSQIAILTRPQGRNGALAQRLHEAGWQTLCLPALRIEPLPPENGAVPLPRDYDLVVFVSGNAARLYLEQLGERGQLPWPAGAVAATVGPASARALLDSGQFGADTTVLHPAETAPTHDSEALWSLLRARPALPRRALLVRGTQGRDWLADRLAAAGVEVSRHAVYRRRPAPWAQEGRQRLRDWARAGERPTWLLTSGEGIDALVQGLREEQLLDWWLQGRFVVTHPVLAERLRALAGGGADAPMVKNCMPADEAIFATFVAA
>NZ_AP014582.1|WP_003812742.1|2166545_2167490_+|hydroxymethylbilane-synthase
MAAVERLTIATRASRLALWQAEHVRDLLRARYPACSVELLTLTTRGDQILDRTLSKVGGKGLFVKELETALLDGRADLAVHSLKDVPVDLHAPFELSCVLERADPRDAFVSNDYGSLADLPPGAAVGTSSLRRESQIRARYPHLVVKPLRGNLDTRLGKLDNGDYAAIVLAAAGLERLGLAARIRALLEPADSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAERAVSRMLGGSCQVPLAAYARIDGDELALRALVAAPDGRRIVRAERRGPRDQAQAIGESAARDLLADGADAILAELLPTSPAP
>NZ_AP014582.1|WP_010930986.1|2165707_2166427_+|TerC-family-protein
MLEFFQTLSWAAVFQIILIDILLGGDNAVVIALACRNLAPKQRMQGILWGTAGAIILRVVLIAFALTLLNIPFLKVVGGLLLVWIGVKLLVPEDEGHDSIKGGTSIVAAVKTIIIADFVMSLDNVIAIAGAAQNAHADHQIGLVVFGLVVSVPIIIWGSTLVLKLIDRFPMVVTFGAALLGWIAGGMLITDVFVVRQFGEQPSAVKIGVEIAGALLVVLLGRWLASRKTASKESVNESA
>NZ_AP014582.1|WP_003812745.1|2164853_2165549_+|TerC-family-protein
MELSSAAFWIALLQIIWVNILLSGDNAVVIALAARSLPPDQQKKAIVVGSAAAIVMRIVLTLVAAKLLLLPWLKLIGAALLVYIGVSLLLPEGEDDGAEKGHGSLLVAIRTIMIADLVMSLDNVVAVAAAAMGDTTLLVLGLAISIPLVIFGSALLLKVIERFPIIVWVGAALLGFIAGELLVGDPALEESVARIDTMLGVTQHDFALMVGAIGAILVLALGKIFQARQRA
>NZ_AP014582.1|WP_003812748.1|2163696_2164578_+|succinate--CoA-ligase-subunit-alpha
MSILINKDTKVITQGITGKTGQFHTRMCREYANGKAAFVAGVNPKKAGEDFEGVPIYANVKDAKADTGATVSVIYVPPAGAAAAIWEAVEAELDLVICITEGIPVRDMLEVKNRMQAMNSKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGIVSRSGTLTYEAVAQVTELGLGQSSAVGIGGDPINGLKHVDVLKLFNDDPDTDAVIMIGEIGGPDEVNAAQWAKDNMKKPVVGFIAGVTAPAGKRMGHAGALISGGADTADAKLEVMEACGIRTTRNPSEMGKLLKSVL
>NZ_AP014582.1|WP_003812728.1|2173091_2173355_+|membrane-protein
MSVKQRQLGQGMTEYIIVVALVAVAAIAVYQLFGQVVRSQTAAMARELAGEDGSAQARAAQSAAGRAASQTRARSLKSFTGNAQGAK
>NZ_AP014582.1|WP_010928268.1|2173351_2174668_+|hypothetical-protein
MRPTRAAVTRQAGQALALGLALMALAGMAWLALYGLGQRAGARAQLLRATDAAAYSGAVVQARALNLLAYIHRAQVGHQVALAHLASLAAWARFAQTQAARRTAQNPPVALIGLLFGPRAARGYGAAHDALAGDLMQAYAAHDELAHRVLQQAADTLARDARATRDATMRAVLRAHYPQGDDGLTLEVLRDDWPGYLRRVPGTSARGLRGWAQRAAGYFDFLQPRDFTREGNWIVSPRCPTRRHELRRRGVTWLDRDGRWGASDTLSFHAVRSNRWIGCYFREYAMGWGLAADSGATRAGPHVLRAPEDFSQQDFWRWVHRHTSWSLLGGRHNPLALSYAASRRLSPGGRGLPAVYEPASSSEAAVGFEIRTQRREEGIVLSARAAGQSHFSLPPGTSVARGRPDVLFLPYWQARRAAADAALPMAARRTVRGPESRP
>NZ_AP014582.1|WP_015064057.1|2174664_2175288_+|hypothetical-protein
MRGAAFSRRQRGQALAEALPLLAMLLLAWAAVAWLGTLRHQALRLGQHSRVAAFMAAAAAPSAPRTATLARQAGLAGRTAADGMPALLARDWLQVDTRLLHAQAAEPAAMPGGLLREGAIAAALRGVTVLAIGPGHASDARAGNDRLARSVAGWQLAHRAAAPAVAATRRRVRPVEAAWGLRDAGQDWLRTWADMASADGAVLRRQP
>NZ_AP014582.1|WP_015064056.1|2175284_2175941_+|hypothetical-protein
MTPAHLAASASAWLHLPPGVVAAALAGQIQMFGVPAEVRVFHAPQGIDALLAHFATRHAELRDLTVLPGLAVLAGGAGDCTHTISLAPQSGGVEGVAARLCWPRGLPSRQPLADVLLPPHARLRLDVATRDGPVSVAQQVWHWRAAGPTETARWAVRREARLRASGWRLQGAAGPACRCGAPQTWLRAGPQGRERLSLQPALHANGCGMRLLHIGGAP
>NZ_AP014582.1|WP_015064055.1|2175937_2176783_+|Flp-pilus-assembly-protein-CpaB
MRAARWRQGLRALGGYAFALVAGSLAAWAAREHIQRRVHDIEQQARVPMVASLVAARDLEAGTPLHDELVAVRDMPQAWLPAGALLPDEAARLDGAVLRAPVKAGEALQAALLSYPEQTPALTEQLEAGQGAITLPLQELPGLSAAARPGDLVDLYVSFTHRQRQLTMPLLAGSKVLALDPADAQGGASTITLRASAREVARLVAARQEGTLTAVLRRAGAPAQGPARAFAAPSAREAGDLPALLGMPRDAAPRAAVPVLYGDRLDAPAGALPGDTEAVMP
>NZ_AP014582.1|WP_015064054.1|2176779_2178192_+|pilus-assembly-protein-N-terminal-domain-containing-protein
MSMRSRLPLHARGWLPWMAVLLAGGSMLWTPGGRAASPAQPAVLRMEVGETQVLAAAGVTRVAVGNGQVLSATVVDGAEVALFARQPGTSSVHIWSGRGARQAYAVEVLPAGRRRLREEVAALLARIPRARSSAVGAHIVIEGSQLSEDDHARIATLAQRYPEVLDFTGRVGWDRMVLLDVQVVELPRQSLRELGLRWDEPAAGGVHAGAVWNGGSAALAPPPGPLAGAAAVRHAGGLLGVNALLSARLSALAQRGEAVLLAQPQLLARSGATASFQAGGELPYRATDKEGNGTTLFKPYGVSLQITPRIDADGAVHARIEVEASSVDPTLALAAGPALRKRRAVTEFNVHSGQTLVLGGFLSRERSHEEKGLPWLSELPLIGALFGARRAALRETELAIFVTPTIVSPSDSFLQRRALLGQMQLDQAFPEAPRLGTGAAADQSADWSRPGGAGSQWRQPPSADAQEGAP
>NZ_AP014582.1|WP_015064053.1|2178188_2179805_+|Flp-pilus-assembly-complex-ATPase-component-TadA
MNVLELALHFEDGARRRMRLAAPVTIGRGAQCALRIANWRVGRVHARLSCLDGAVVLEDLGTLGGTSVNGLRVATHAPVLPDDEIVIGPCLIRVSACCTGSAPSPAPAALPAGGASRGEDLDAALQQSLVLLPHRRRLHAALLEALDLRRRDVSAMSDRMLRAQAEQRLVELVGQDGELPEGIDRAQLCRAVLDEAVGLGPLEPLLADGGISEIMVNRHDEIYVERAGRLQRHAAAFSSEQAVRWVVERIVAPLGRRIDDSSPMVDARLPDGSRVNAVIAPIAIRGVSLTIRKFPRQRPGMADLLAAGSLSEPMARFLLQCVHARKNLLVSGGTGSGKTTLLNILSNAIPEGERIVTIEDAAELRLDHAHLVALEARPANAEGRGRVDIRDLVRNALRMRPDRIVVGECRGAEAFDMLTAMNTGHEGSLTTLHANTPRDALARLEAMTLMAGLDLPLPVVREHIAASIDIIVQQARMADGRRIVTAIVEIAGMESGRIQTQELFRYDARHGFIAGDAPVLADGAWARGPFTGQPEPAP
>NZ_AP014582.1|WP_003812713.1|2179801_2180647_+|type-II-secretion-system-F-family-protein
MIWLAMGMAMAAAAWLAWRVLAWSGPAARRYRAVYTQQAGAHLSEVFLFVDPAQLWAAALAMAAAGAAAAWVFSGSAWLAAVAAVALLRLPHLLLGAARRRRLRQLERQLPGALVAMACALRAGAGIAAALRQLVEHGEAPLAQEFGLLLREQRMGVSFDAALARLARRASFESMALVAAALRVAAHTGGNLAETLEGIAQTVSARLQLQDRVRALCAQGRMQAWIVGALPPVLMGVLGRLQPEAMAALWHTLYGWAALALIVVLEGTGIWLIRRIVAIDV
>NZ_AP014582.1|WP_015064052.1|2180657_2181554_+|type-II-secretion-system-F-family-protein
MWLWLAASVAGVAAGWACLALLRGWCGAGWAAACGPEPAPGPPAWRLPRIWRCCRPWLGPLLPWCDRLLSWRMRAVIERAIVRAGCDGLVRPCEVAALSLWMAWLGGVVAVTAASLADGWRAWLPLAPAACAAGAWPALWLRRCAARRRQRIARELPFILDLMTLCAEAGLGMHGALQQAASHGPPGPLRELLVQALCDMRAGMPRRQAMQALAARADSPPVRAWVGALAHADAQGMSLGPMLRGLATRYRAERHQRAERLAMEAPVKMLLPLIACIFPCTFIVLAFPIGYALLQGGL
>NZ_AP014582.1|WP_161781140.1|2181553_2182261_+|DUF192-domain-containing-protein
MRLRLRLARARGWRGRLVGLLGRRRPPGPRSGLLLAPCRAVHTWGMAYAIDVAFVGRDGRVLRLVRGLRPWRGALCVRAVAVVETRVGVIDPEHGGIGRVEAAIQHAARDDGDGNLQGAGQRVGHAHADQQADAQVDEQEHQDPDHAVHQERPFVAPAGNTREEQRLQQPQAVPAHQHGSMPEHGGDDHVKRGEHQQRRAHGRHDGREVVGRGHADAFGQRTGKRQERQQAGGQA

Crispr_ID: NZ_AP014582_4

• CRISPR_ID: NZ_AP014582_4
• CRISPR_location: 2296773-2296900
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP014582_4

Consensus_repeat	Method
CTCGGGGGGCAGCAAGCCCGCATAGCGGGCGCAGCGTGGGGGC	CRISPRCasFinder

spacers of NZ_AP014582_4

>4.1|2296816|42|NZ_AP014582|CRISPRCasFinder
ACTACTTTGCCGCTGGGCCGCCCCAAGGCAAAAAAGCCCCCT

CRISPR arrays and Neighbor proteins around NZ_AP014582_4

CRISPR arrays

The CRISPR arrays of NZ_AP014582_4

>merge|NZ_AP014582|4|2296773-2296900|CRISPRCasFinder
CTCGGGGGGCAGCAAGCCCGCATAGCGGGCGCAGCGTGGGGGCACTACTTTGCCGCTGGGCCGCCCCAAGGCAAAAAAGCCCCCTCTCGGGGGGCAGCAAGCCCGCGTAGCGGGCGCAGCGTGGGGGC

>NZ_AP014582|4|4|2296773-2296900|CRISPRCasFinder
CTCGGGGGGCAGCAAGCCCGCATAGCGGGCGCAGCGTGGGGGC	ACTACTTTGCCGCTGGGCCGCCCCAAGGCAAAAAAGCCCCCT
CTCGGGGGGCAGCAAGCCCGCGTAGCGGGCGCAGCGTGGGGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014582.1|WP_015063637.1|2287168_2287972_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|223955
NZ_AP014582.1|WP_003812460.1|2303746_2304157_+|Fe-S-cluster-assembly-scaffold-IscU	unknown	unknown	gnl|CDD|183087
NZ_AP014582.1|WP_003812463.1|2301971_2302484_+|Fe-S-cluster-assembly-transcriptional-regulator-IscR	unknown	unknown	gnl|CDD|273927
NZ_AP014582.1|WP_080704393.1|2295142_2296687_+|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	unknown	unknown	gnl|CDD|273608
NZ_AP014582.1|WP_033451903.1|2297695_2298898_-|aspartate/tyrosine/aromatic-aminotransferase	unknown	unknown	gnl|CDD|181731
NZ_AP014582.1|WP_015063638.1|2288396_2289554_+|thiolase	unknown	unknown	gnl|CDD|180434
NZ_AP014582.1|WP_010926437.1|2293910_2294873_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270296
NZ_AP014582.1|WP_003812456.1|2304484_2304997_+|Fe-S-protein-assembly-co-chaperone-HscB	unknown	unknown	gnl|CDD|235133
NZ_AP014582.1|WP_003812462.1|2302501_2303713_+|IscS-subfamily-cysteine-desulfurase	unknown	unknown	gnl|CDD|184450
NZ_AP014582.1|WP_003812478.1|2293234_2293876_+|CoA-transferase-subunit-B	unknown	unknown	gnl|CDD|188219
NZ_AP014582.1|WP_010930566.1|2296916_2297567_-|transcriptional-repressor-LexA	unknown	unknown	gnl|CDD|234688
NZ_AP014582.1|WP_003812491.1|2287968_2288400_+|OB-fold-domain-containing-protein	unknown	unknown	gnl|CDD|224462
NZ_AP014582.1|WP_003812465.1|2301264_2301756_+|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl|CDD|319971
NZ_AP014582.1|WP_015063640.1|2291533_2292529_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173838
NZ_AP014582.1|WP_003812458.1|2304158_2304482_+|iron-sulfur-cluster-assembly-protein-IscA	unknown	unknown	gnl|CDD|213674
NZ_AP014582.1|WP_010926439.1|2305126_2306989_+|Fe-S-protein-assembly-chaperone-HscA	unknown	unknown	gnl|CDD|235360
NZ_AP014582.1|WP_033450234.1|2290354_2291512_+|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|173841
NZ_AP014582.1|WP_033448623.1|2292573_2293242_+|3-oxoacid-CoA-transferase-subunit-A	unknown	unknown	gnl|CDD|131482
NZ_AP014582.1|WP_033448626.1|2289575_2290352_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235546
NZ_AP014582.1|WP_003812466.1|2298975_2301003_+|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl|CDD|235395

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP014582.1|WP_015063637.1|2287168_2287972_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|223955	COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism].	1.56988e-63
NZ_AP014582.1|WP_003812460.1|2303746_2304157_+|Fe-S-cluster-assembly-scaffold-IscU	gnl|CDD|183087	PRK11325, PRK11325, scaffold protein; Provisional.	5.84746e-99
NZ_AP014582.1|WP_003812463.1|2301971_2302484_+|Fe-S-cluster-assembly-transcriptional-regulator-IscR	gnl|CDD|273927	TIGR02010, Putative_HTH-type_transcriptional_regulator, iron-sulfur cluster assembly transcription factor IscR. This model describes IscR, an iron-sulfur binding transcription factor of the ISC iron-sulfur cluster assembly system. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Regulatory functions, DNA interactions].	1.00126e-77
NZ_AP014582.1|WP_080704393.1|2295142_2296687_+|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	gnl|CDD|273608	TIGR01414, Contains:_AIDA-I_translocator, outer membrane autotransporter barrel domain. A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	1.27065e-84
NZ_AP014582.1|WP_033451903.1|2297695_2298898_-|aspartate/tyrosine/aromatic-aminotransferase	gnl|CDD|181731	PRK09257, PRK09257, aromatic amino acid transaminase.	0
NZ_AP014582.1|WP_015063638.1|2288396_2289554_+|thiolase	gnl|CDD|180434	PRK06158, PRK06158, thiolase; Provisional.	0
NZ_AP014582.1|WP_010926437.1|2293910_2294873_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl|CDD|270296	cd13578, PBP2_Bug27, Aromatic solutes transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. Bug27 binds non-carboxylated solute nicotinamide, in contrast to BugD (aspartic acid transporter) and BugE (glutamate transporter) which both bind aliphatic carboxylated ligands. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity.	2.39297e-140
NZ_AP014582.1|WP_003812456.1|2304484_2304997_+|Fe-S-protein-assembly-co-chaperone-HscB	gnl|CDD|235133	PRK03578, hscB, Fe-S protein assembly co-chaperone HscB.	2.55481e-79
NZ_AP014582.1|WP_003812462.1|2302501_2303713_+|IscS-subfamily-cysteine-desulfurase	gnl|CDD|184450	PRK14012, PRK14012, IscS subfamily cysteine desulfurase.	0
NZ_AP014582.1|WP_003812478.1|2293234_2293876_+|CoA-transferase-subunit-B	gnl|CDD|188219	TIGR02428, 3-oxoadipate_CoA-transferase_subunit_B, 3-oxoacid CoA-transferase, B subunit. Various members of this family are characterized as the B subunits of succinyl-CoA:3-ketoacid-CoA transferase (EC 2.8.3.5), beta-ketoadipate:succinyl-CoA transferase (EC 2.8.3.6), acetyl-CoA:acetoacetate CoA transferase (EC 2.8.3.8), and butyrate-acetoacetate CoA-transferase (EC 2.8.3.9). This represents a very distinct clade with strong sequence conservation within the larger family defined by pfam01144. The A subunit represents a different clade in pfam01144.	3.32577e-117
NZ_AP014582.1|WP_010930566.1|2296916_2297567_-|transcriptional-repressor-LexA	gnl|CDD|234688	PRK00215, PRK00215, transcriptional repressor LexA.	1.25833e-105
NZ_AP014582.1|WP_003812491.1|2287968_2288400_+|OB-fold-domain-containing-protein	gnl|CDD|224462	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only].	1.42164e-21
NZ_AP014582.1|WP_003812465.1|2301264_2301756_+|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl|CDD|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	1.0991e-75
NZ_AP014582.1|WP_015063640.1|2291533_2292529_+|acyl-CoA-dehydrogenase	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	6.3649e-20
NZ_AP014582.1|WP_003812458.1|2304158_2304482_+|iron-sulfur-cluster-assembly-protein-IscA	gnl|CDD|213674	TIGR02011, Protein_yfhF., iron-sulfur cluster assembly protein IscA. This model represents the IscA component of the ISC system for iron-sulfur cluster assembly. The ISC system consists of IscRASU, HscAB and an Isc-specific ferredoxin. IscA previously was believed to act as a scaffold and now is seen as an iron donor protein. This clade is limited to the proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	4.04388e-54
NZ_AP014582.1|WP_010926439.1|2305126_2306989_+|Fe-S-protein-assembly-chaperone-HscA	gnl|CDD|235360	PRK05183, hscA, chaperone protein HscA; Provisional.	0
NZ_AP014582.1|WP_033450234.1|2290354_2291512_+|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	1.65925e-78
NZ_AP014582.1|WP_033448623.1|2292573_2293242_+|3-oxoacid-CoA-transferase-subunit-A	gnl|CDD|131482	TIGR02429, 3-oxoadipate_CoA-transferase_subunit_A, 3-oxoacid CoA-transferase, A subunit. Various members of this family are characterized as the A subunits of succinyl-CoA:3-ketoacid-CoA transferase (EC 2.8.3.5), beta-ketoadipate:succinyl-CoA transferase (EC 2.8.3.6), acetyl-CoA:acetoacetate CoA transferase (EC 2.8.3.8), and butyrate-acetoacetate CoA-transferase (EC 2.8.3.9). This represents a very distinct clade with strong sequence conservation within the larger family defined by pfam01144. The B subunit represents a different clade in pfam01144, described by TIGR02428. The two are found in general as tandem genes and occasionally as a fusion.	7.77411e-142
NZ_AP014582.1|WP_033448626.1|2289575_2290352_+|SDR-family-oxidoreductase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	4.8895e-80
NZ_AP014582.1|WP_003812466.1|2298975_2301003_+|excinuclease-ABC-subunit-UvrB	gnl|CDD|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0

Protein sequences

>NZ_AP014582.1|WP_080704393.1|2295142_2296687_+|autotransporter-outer-membrane-beta-barrel-domain-containing-protein
MDVTPLLPMPSDSSISCKSRSRSMALARRRLAWPGVCGALSLAAWLAPAQAQSAMAASGPQDAPAVSIPVLDGWPVDDESGWTTIDLDGTAIDDGWTHIDIPRPELDGAPVDSEDGRLPSPPEEAPQAGPDASKQRPEGLPAPDANPQPDAKPGAEMKPGPGVEPGSEAEPGPQGQPGPQPGARPQDEPHAQPLPPAGNPGAGIYMPRSGILTAPVLAVLGTASAPQGIWQAEMNALSKRMGELRLTPAAGGVWARSFAQRQRLDNQVVDRFTQTVGGIEIGADTALPAAEGRWHVGAVAGYSRARRKLAHSARGNSDSLHVGAYATYIGDGGFYLDGIVRVNRYEHDFKADGQRGARVTGKYRANGIGLSLETGRRFTWAGDWFVEPQVEVALFRSGGADYTASNGVRVDVASTKSLLGRAGLQVGRKLDLGNGKLVQPYAKLSWLQEFDGVGKVRTNDIGHDVKLRGGRAELDLGVAAALGRHSSLFASYEYSKGSRLTIPWSFHVGYRYAW
>NZ_AP014582.1|WP_010926437.1|2293910_2294873_+|tripartite-tricarboxylate-transporter-substrate-binding-protein
MKTKIKIVTLALCAFSSAVFASSFPSKPINLIVPYPPGGAVDPIARLYAEKISQSWGVPVIVLNRPGAGTTIGLNQAARAEPDGYTVVLGTASITSNAPLYRSLPYDTLKDFTYLSMAGMIPLAITANPRTAVNSMDELVGQLKKKPGSLTYSSSGNGTIIHLGGELFKSLAGVDMVHVPYKGSGPSVMAGVAGEVDLTFDSVFLMDPQVKAGKLKYIAVASEKRLKSLPEVPAIGEKYPGYFVTSWVGFMGPAGIPADITAAWAKEIARVAALPDVSEKLATLGVESVSSTPQQFSAFVESEIRKWEKVVQDAHIPPVQ
>NZ_AP014582.1|WP_003812478.1|2293234_2293876_+|CoA-transferase-subunit-B
MSKGWSNDEIAARIAVDLPEHAIVNLGIGLPILVANHIPEGKTIFFHSENGIIGLGPVPAPGQEDPDIVNAAKKHATLIAGASIVHHADSFSLIRGGRLDYSVLGGLQVSSGGDIANWKVPGQKGGGGVGGAMDLAVGARNVLVMMRHQDKTGASKLVKSCTFPLTAVSAVTRVYTELGIFECAGDAFIVRESAPGIGKDELLRKTEAALTFP
>NZ_AP014582.1|WP_033448623.1|2292573_2293242_+|3-oxoacid-CoA-transferase-subunit-A
MLNKTCESADEAVSVVESGATILISGFGDIGLPFELLHALARTSVKDLTIVSNNAGTGELGLSRLFRNRQVSRLIASFPSQPDSHHYFAAYQEGLVDLELVPQGTLAERIRAAGAGLAGFFTPTGYGTELAQGKECRMFKGKGYVFEEALPGDFAFIKAHVADAYGNLRYRRASRTFNPIMAMAARTTIAEAKQMVPVGSIDPDDVHTPGVFVDRIVEVRDE
>NZ_AP014582.1|WP_015063640.1|2291533_2292529_+|acyl-CoA-dehydrogenase
MYSDAFEDLLKGRCEPAVVRAIEAGGDVQALWNAIVQSGFLDLMAPEQAGGAAADLADALPLFTALGAYAVPLPVGQAIALRTLLPAGMEVPGGLPSFAPALRTGPDGALRAPRVPYGMLAGPVLGELDGALCLLDARAAQRRDCGLHGEPTADLSWDAGVRQDAVRRLDDAGGAPGRLAAWGAALHAALLTGAMTRCFEMSLQYGNDRTQFGRSIGKFQAVQHQLAVMAEHVAAARIATAAAFRAGLAQPALLPAAIAKARASEAAALAANTAHAVHGAIGVTEEYDLQLYTRRLHGWRLAHGSEAYWHQVVGAALMGSGDGAVQFVRGL
>NZ_AP014582.1|WP_033450234.1|2290354_2291512_+|acyl-CoA-dehydrogenase-family-protein
MSALIDRFELAELPARAQAFRQDVQAFLKAELPPLPADRRARSWMGFDAGFSRKLAARGWVGVTLPRAYGGAEMDAFSRFVLIEELLCAGAPVSAHWIADRQSGPQIRKFGSEAQRSFYLPRICRGEAFFCIGMSEPNSGSDLASVGTRATRRADGGWTLSGRKIWTTNAQHCHYMIALVRTSGTPQDRNQGLSQFIVDLSLPGVTVRPISDLAGDAHFSEVFFDDVQLSDEALIGQEGSGWEQVTAELAFERSGPERIYSSMVLLDGWIQWLRGRGDVSQTAAVGRYATHLAALRNLSLSVTARLAAGESPVVEAALVKELGTTFEQEIPAAIEAALGSDPGADIDAELLRTCAYVNQVCPTYSLRGGTREILRGMIARGLGLR
>NZ_AP014582.1|WP_033448626.1|2289575_2290352_+|SDR-family-oxidoreductase
MQDKLLTLENRQVIVTGAGQGIGRALASAIAELGGRVVAVDLNADALAALREALGHERCVTVAGNVADPSLAQQAVDAGVTAFGGVNGLVNNAGVTRTAMIDKMSISDWQQVIDVHLSGSFYFLQALGRHLLGRAKAGGDGAGAIVNISSDAGRRGTIGQINYGAAKAGVLGLTMCAAREWARYGIRTNTVGFGVVETPMTETIRGEKFRDTYLSQIPLGRWGEADEVVRPVCFLLSDAASYVTGQHLSVNGGYTIGL
>NZ_AP014582.1|WP_015063638.1|2288396_2289554_+|thiolase
MIQERFPRGKTAIVACATYGIGESPGLSSLDLAVRASVQALDSVDLTPADVDGLFIGLPDDFVSGLSFTEYLGISPRLTDNNRTGGSSFLTHAIHAALALEAGLCDVALIAYGSNQRSGAGKLVSSMRPSPYEGAYKLARPVGAYALAASRYAAQYGLKKEQLGAVALAARQWAQKNPEAYMRAPLTMDEYLASRLVCDPFSVRDCCLVTDGAAAVVMVRADRARDLAARPAYLLGGAAAAWHKDITNMPDLTVTAASLSGPRAMAQAGVTPADIDVLELYDAFTLNTILFLEDLGFCAKGEGGAFVEDGRIAPGGALPVNTNGGGLSCVHPGMYGLFTMVEAAQQLAGAAGERQVAQARLALAHGNGGELSSQATLILGTEETI
>NZ_AP014582.1|WP_003812491.1|2287968_2288400_+|OB-fold-domain-containing-protein
MTEHPQAASALLPQQEYFAHLADGRFMIQRSRSSGEYVFYPRVAAPRTGAQDLEWVAASGRGTVYATTVMRVRPPAAPYNVCLVELEEGPRMMSRVEGIGPEDVQVGMAVRARIIRDDAGEPLVVFEPAGPSDAGIGQGRAAQ
>NZ_AP014582.1|WP_015063637.1|2287168_2287972_+|enoyl-CoA-hydratase/isomerase-family-protein
MIMSVLEISRVGACAVLTLNRPAARNALDMDLRNALAKALPEIRDDATVRAVVLTGAGGHFCAGGDIRAIAAGQGNADVFEGRNRILSMQRWFDGLVDLEKPVIAAVDGVAFGAGLSLALAADFVLASPRATFCAVFARLGYVPDLGGMYLLPRAVGLARAKALAFSARVVGAPEALEMGIAHQLVDDRPVLDAALELAGRFEQAPAGALGIVKSVMNHAFESDRRTVYMQEALAQALCRESAFHQEAARRFLDKQAPLYQWPQEQQ
>NZ_AP014582.1|WP_010930566.1|2296916_2297567_-|transcriptional-repressor-LexA
MATKLTERQQEILDLIRQTVARTGFPPTRAEIAQALGFRSPNAAEDHLKALARKGAIELTAGASRGIRLKVPDSATPSAQLTHPLLAQLVLPLVGRVAAGSPILASEHVEREVGVDPGLFAQTPDYLLKVRGMSMRDAGILEGDLLAVKRAAEARNGQIVVARLGDEVTVKRLQRQNGRIELLPENPDFAPIVVANTDEFALEGIAVGLIRTQPLH
>NZ_AP014582.1|WP_033451903.1|2297695_2298898_-|aspartate/tyrosine/aromatic-aminotransferase
MSTLFASVELAPRDPILGLNEQYNADTRPGKVNLGVGVYYDDEGRIPLLQAVRKAEVARIEAAAARGYLPIEGIAGYNKGAQALLLGADSPLAAEGRVLTAQALGGTGALKIGADFLRQLLPQSKVLISDPSWENHRALFERAGFPVETYAYYDAATHGLNFEAMLAALQAAPEQTIVVLHACCHNPTGVDPTPQQWEQIAAVVKARNLVPFLDIAYQGFGEGLEQDAAVVRMFAALDLTMFISSSFSKSFSLYGERVGALTVVAGSKDEAARVLSQLKRVIRTNYSNPPTHGGTVVSTVLNTPELFALWENELAGMRDRIRLMRKELVEKIKAQGVAQDFSFVLAQRGMFSYSGLTATQVDRLREEHGIYAVSSGRICVAALNSRNIDAVAAGIAAVLK
>NZ_AP014582.1|WP_003812466.1|2298975_2301003_+|excinuclease-ABC-subunit-UvrB
MTAPGFVEFPDSPFHLYQPYPPAGDQPGAIDALTEGVSDGLMFQTLLGVTGSGKTYTMANMIARLGRPALVLAPNKTLAAQLYAEMREFFPRNAVEYFVSYYDYYQPEAYVPTRDLFIEKDSSINEHIEQMRLSATKSLLERRDTVIVGTVSCIYGIGNPGDYHAMVLILRTGDRISRREVLARLVAMQYTRNDADFTRGVFRVRGETIDIFPAESPELALRLTLFDDEIESLELFDPLTGRVRQKLPRFTVYPGSHYVTPRETVLRAIETIKEELRERLAQLIADGKLVEAQRLEQRTRFDLEMLQELGFCKGIENYSRHLSGAAPGEPPPTLIDYLPADALMFIDESHVTIGQLGGMYRGDRSRKETLVQYGFRLPSALDNRPLRLEEFEARMRQCVFVSATPAAYEQEHADNVVEQVVRPTGLVDPIVEVRPAHTQVDDLLGEIHKRAALQERVLVTTLTKRMAEDLTDFLSEHGVRVRYLHSDIDTVERVEIIRDLRLGVFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGRAILYADRITDSMRRAIDETERRRAKQIQHNTDHGITARGVSKAVRELIDGVVAPAGHDALESAVPAEVLTDEKAMAREIRRLEKLMMDHARNLEFEQAAAARDALNALKSRLLLDGVG
>NZ_AP014582.1|WP_003812465.1|2301264_2301756_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MMTKVLFVCMGNICRSPSAEGVFRHLVNDAGMGDVVRVDSAGTHAFHIGEAPDARAQAAARKRGYDLTHCAARQVTADDFREFDLILAMDWDNLAALQQQCPKAYQHKLMLLMRFANEFEEATVPDPYYGGPEGFGKVLDYLEDACQGVLELVRKRATQYQAA
>NZ_AP014582.1|WP_003812463.1|2301971_2302484_+|Fe-S-cluster-assembly-transcriptional-regulator-IscR
MRLTTKGRFAVTAMIDLAMRQHSGPVTLAAISQRQNISLSYLEQLFGKLRRHELVDSVRGPGGGYSLARLARNVTVADIIFAVDEPLDATSCGGKRDCTSGNDGKPGKCMTHELWTTLNRKMVDYLDSVSLQDLVDQQRVRQLQEAANQAQGCSAVRVNRSTPVAANATA
>NZ_AP014582.1|WP_003812462.1|2302501_2303713_+|IscS-subfamily-cysteine-desulfurase
MSNRPIYLDYSATTPVDPRVVEKMIPWLYESFGNPASRSHAFGWEAEDAVEKAREEVAKLVNADPREIVWTSGATESDNLAIKGAANFYAERGKHIITVKTEHKAVLDTCRELERQGFEVTYLDVQDDGLLSLDAFKAALRPDTILVSVMMVNNEIGVIQDIAALGEICREKGIIFHVDAAQATGKVEIDLQKLKVDLMSFSAHKTYGPKGIGALYVRRKPRVRIEAQMHGGGHERGFRSGTLATHQIVGMGEAFRLAREEMGTENERVRMLRDRLLAGLTQIEEVYVNGSMEHRVPHNLNISFNYVEGESLIMAIKELAVSSGSACTSASLEPSYVLRALGRNDELAHSSIRFTLGRFTTEQEIDFTIELIKSRVGKLRDMSPLWEMAQEGIDLNSVQWAAH
>NZ_AP014582.1|WP_003812460.1|2303746_2304157_+|Fe-S-cluster-assembly-scaffold-IscU
MAYSSKVLDHYENPRNVGSFDKGDDSVGTGMVGAPACGDVMKLQIKVNEAGVIEDARFKTYGCGSAIASSSLVTEWVKGKTLDEAMNIRNTQIAEELALPPVKIHCSILAEDAIKAAVQDYKTKHGAETPEAVAAN
>NZ_AP014582.1|WP_003812458.1|2304158_2304482_+|iron-sulfur-cluster-assembly-protein-IscA
MAVTLTQSAANHVGRYLQKRGKGIGLRLGVRTTGCSGMAYKLEYVDEQAADDVVFDSFGVKVFIDPKSLAYLDGTELDYAREGLNEGFRFSNPNEKATCGCGESFTV
>NZ_AP014582.1|WP_003812456.1|2304484_2304997_+|Fe-S-protein-assembly-co-chaperone-HscB
MAADDHFSLFGLPTRFALDPVQLEQAWRAVAARVHPDRYATASAAERRVAMQWAARANEAYRQLRDPMLRARYLCEQAGVDLQTESNTAMDPAFLMQQMEWREMLDDARRDPAAFAALRAELEQARLRMQQTLSELIDERGDYQQAGTKVREWMFVEKLAQELSAAQPMQ
>NZ_AP014582.1|WP_010926439.1|2305126_2306989_+|Fe-S-protein-assembly-chaperone-HscA
MALLQISEPGDSPAPHQRKLAVGIDLGTTNSLVAAVRSSVPEVLADAQGQVLLPSAVRYLDGGAVRIGREALLEQARDPLNTIVSVKRFMGRSAADAVASGAPYEFVDAPGMVRLRTVQGDLSPVEVSAQILAVLRQRAEDVLGDDLVGAVITVPAYFDDAQRQATRDAARLAGLNVLRLLNEPTAAAIAYGLDQAAEGIYAVYDLGGGTFDISILRLTQGVFEVIATGGDTALGGDDFDSAIVAHACAGEDVAALPVADRRALLVAARAAREALTDQAQAPFEVTLRDGRAIQATLTRAQFEQLAEPLVGRTLDSARRALRDAGLAVGDVRGVVMVGGATRMPVVRQQVGALFGTEPLTNLDPDQVVALGAALQANLLAGNRAPGEDWLLLDVIPLSLGLETMGGLVERIIPRNSTIPVARAQEFTTFKDGQTAMSVHVVQGERDLVSDCRSLARFELRGIPPMVAGAARIRVTFQVDADGLLSVTAREQSTGVEAAVAVKPSYGLSDDEIARMLADSVTQADSDARARMLREQQVEARQLVESVGAALAADGDLLDPAERATVDQRLQAAAQAQSLDDVEAVRAAVQALSDATEEFAARRMDRSIRAALAGRKLDELA

Crispr_ID: NZ_AP014582_5

• CRISPR_ID: NZ_AP014582_5
• CRISPR_location: 3074009-3074170
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP014582_5

Consensus_repeat	Method
CGGGGCGGAAGCGGCTGAGCCGTTTCGACCTTCGGCCGCGGCACGACTTCCACC	CRISPRCasFinder

spacers of NZ_AP014582_5

>5.1|3074063|54|NZ_AP014582|CRISPRCasFinder
TTGGCGACCTCCACCTTGGGAGGCACCATCGGCACCGCCTTGGCCGGCACTGGT

CRISPR arrays and Neighbor proteins around NZ_AP014582_5

CRISPR arrays

The CRISPR arrays of NZ_AP014582_5

>merge|NZ_AP014582|5|3074009-3074170|CRISPRCasFinder
CGGGGCGGAAGCGGCTGAGCCGTTTCGACCTTCGGCCGCGGCACGACTTCCACCTTGGCGACCTCCACCTTGGGAGGCACCATCGGCACCGCCTTGGCCGGCACTGGTCGGGGCGGAAGCGGCTGGGCCGTTTCGACCTTCGGCCGCGGCACGACTTCCACC

>NZ_AP014582|5|5|3074009-3074170|CRISPRCasFinder
CGGGGCGGAAGCGGCTGAGCCGTTTCGACCTTCGGCCGCGGCACGACTTCCACC	TTGGCGACCTCCACCTTGGGAGGCACCATCGGCACCGCCTTGGCCGGCACTGGT
CGGGGCGGAAGCGGCTGGGCCGTTTCGACCTTCGGCCGCGGCACGACTTCCACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014582.1|WP_003811059.1|3094696_3095317_-|TRAP-transporter-small-permease	unknown	unknown	gnl|CDD|377284
NZ_AP014582.1|WP_033452387.1|3065892_3067644_-|filamentous-hemagglutinin-transporter-protein-FhaC	unknown	unknown	gnl|CDD|377148
NZ_AP014582.1|WP_010930616.1|3063091_3064066_+|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270320
NZ_AP014582.1|WP_003811089.1|3064072_3064573_+|TRAP-transporter-small-permease	unknown	unknown	gnl|CDD|377284
NZ_AP014582.1|WP_003811052.1|3097830_3098793_+|DMT-family-transporter	unknown	unknown	gnl|CDD|223769
NZ_AP014582.1|WP_033452384.1|3064565_3065867_+|TRAP-transporter-large-permease-subunit	unknown	unknown	gnl|CDD|129868
NZ_AP014582.1|WP_010930609.1|3085002_3085632_+|virulence-factors-two-component-system-response-regulator-BvgA	unknown	unknown	gnl|CDD|225107
NZ_AP014582.1|WP_003811069.1|3089403_3090279_-|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|376350
NZ_AP014582.1|WP_015063873.1|3068747_3071369_-|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl|CDD|225729
NZ_AP014582.1|WP_003811078.1|3072415_3073021_-|fimbrial-protein	unknown	unknown	gnl|CDD|339870
NZ_AP014582.1|WP_003811063.1|3092674_3093394_-|DUF2848-domain-containing-protein	unknown	unknown	gnl|CDD|371339
NZ_AP014582.1|WP_010930607.1|3090412_3091207_-|putative-hydro-lyase	unknown	unknown	gnl|CDD|180100
NZ_AP014582.1|WP_003811094.1|3061045_3061537_+|TRAP-transporter-small-permease	unknown	unknown	gnl|CDD|377284
NZ_AP014582.1|WP_033452391.1|3091264_3092614_-|amidase	unknown	unknown	gnl|CDD|235921
NZ_AP014582.1|WP_172452891.1|3067636_3068767_-|fimbrial-protein	unknown	unknown	gnl|CDD|226069
NZ_AP014582.1|WP_003811061.1|3093416_3094700_-|TRAP-transporter-large-permease	unknown	unknown	gnl|CDD|224509
NZ_AP014582.1|WP_003811072.1|3085640_3089357_+|virulence-factors-two-component-system-sensor-histidine-kinase-BvgS	unknown	unknown	gnl|CDD|182169
NZ_AP014582.1|WP_003811054.1|3096818_3097727_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_AP014582.1|WP_003811093.1|3061529_3062828_+|TRAP-transporter-large-permease-subunit	unknown	unknown	gnl|CDD|129868
NZ_AP014582.1|WP_138142578.1|3071431_3072166_-|molecular-chaperone-FimB	unknown	unknown	gnl|CDD|225663

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP014582.1|WP_003811059.1|3094696_3095317_-|TRAP-transporter-small-permease	gnl|CDD|377284	pfam04290, DctQ, Tripartite ATP-independent periplasmic transporters, DctQ component. The function of the members of this family is unknown, but DctQ homologs are invariably found in the tripartite ATP-independent periplasmic transporters.	1.22416e-16
NZ_AP014582.1|WP_033452387.1|3065892_3067644_-|filamentous-hemagglutinin-transporter-protein-FhaC	gnl|CDD|377148	pfam03865, ShlB, Haemolysin secretion/activation protein ShlB/FhaC/HecB. This family represents a group of sequences that are related to ShlB from Serratia marcescens. ShlB is an outer membrane protein pore involved in the Type Vb or Two-partner secretion system where it is functions to secrete and activate the haemolysin ShlA. The activation of ShlA occurs during secretion when ShlB imposes a conformational change in the inactive haemolysin to form the active protein.	3.83104e-92
NZ_AP014582.1|WP_010930616.1|3063091_3064066_+|TRAP-transporter-substrate-binding-protein	gnl|CDD|270320	cd13602, PBP2_TRAP_BpDctp6_7, Substrate-binding domain of a pyroglutamic acid binding DctP subfamily of the tripartite ATP-independent periplasmic transporters; contains the type 2 periplasmic binding protein fold. DctP6 and DctP7 groups of the TRAP transporters that involved in pyroglutamic acid transport. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.1715e-122
NZ_AP014582.1|WP_003811089.1|3064072_3064573_+|TRAP-transporter-small-permease	gnl|CDD|377284	pfam04290, DctQ, Tripartite ATP-independent periplasmic transporters, DctQ component. The function of the members of this family is unknown, but DctQ homologs are invariably found in the tripartite ATP-independent periplasmic transporters.	1.01797e-16
NZ_AP014582.1|WP_003811052.1|3097830_3098793_+|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	5.74276e-16
NZ_AP014582.1|WP_033452384.1|3064565_3065867_+|TRAP-transporter-large-permease-subunit	gnl|CDD|129868	TIGR00786, TRAP_transporter_permease_protein_SiaT, TRAP transporter, DctM subunit. The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family (TC 2.A.56)- DctM subunit TRAP-T family permeases generally consist of three components, and these systems have so far been found in Gram-negative bacteria, Gram-postive bacteria and archaea. Only one member of the family has been both sequenced and functionally characterized. This system is the DctPQM system of Rhodobacter capsulatus (Forward et al., 1997). DctP is a periplasmic dicarboxylate (malate, fumarate, succinate) binding receptor that is biochemically well-characterized. DctQ is an integral cytoplasmic membrane protein with 4 putative transmembrane a-helical spanners (TMSs). DctM is a second integral cytoplasmic membrane protein with 12 putative TMSs. These proteins have been shown to be both necessary and sufficient for the proton motive force-dependent uptake of dicarboxylates into R. capsulatus. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.12016e-125
NZ_AP014582.1|WP_010930609.1|3085002_3085632_+|virulence-factors-two-component-system-response-regulator-BvgA	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.75971e-63
NZ_AP014582.1|WP_003811069.1|3089403_3090279_-|EAL-domain-containing-protein	gnl|CDD|376350	pfam00563, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.	1.53847e-49
NZ_AP014582.1|WP_015063873.1|3068747_3071369_-|fimbrial-biogenesis-outer-membrane-usher-protein	gnl|CDD|225729	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_AP014582.1|WP_003811078.1|3072415_3073021_-|fimbrial-protein	gnl|CDD|339870	pfam16970, FimA, Type-1 fimbrial protein, A. FimA is a family of Gram-negative fimbrial component A proteins that form part of the pili. There are usually up to 1000 copies of this subunit in one pilus that form a helically wound rod onto which the tip fibrillum (FimF.FimG, FimH) is attached. Pilus subunits are translocated from the cytoplasm to the periplasm via the general secretory pathway SecYEG.	7.01167e-69
NZ_AP014582.1|WP_003811063.1|3092674_3093394_-|DUF2848-domain-containing-protein	gnl|CDD|371339	pfam11010, DUF2848, Protein of unknown function (DUF2848). This bacterial family of proteins has no known function.	4.73124e-91
NZ_AP014582.1|WP_010930607.1|3090412_3091207_-|putative-hydro-lyase	gnl|CDD|180100	PRK05463, PRK05463, putative hydro-lyase.	0
NZ_AP014582.1|WP_003811094.1|3061045_3061537_+|TRAP-transporter-small-permease	gnl|CDD|377284	pfam04290, DctQ, Tripartite ATP-independent periplasmic transporters, DctQ component. The function of the members of this family is unknown, but DctQ homologs are invariably found in the tripartite ATP-independent periplasmic transporters.	1.90947e-16
NZ_AP014582.1|WP_033452391.1|3091264_3092614_-|amidase	gnl|CDD|235921	PRK07056, PRK07056, amidase; Provisional.	0
NZ_AP014582.1|WP_172452891.1|3067636_3068767_-|fimbrial-protein	gnl|CDD|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	9.52426e-07
NZ_AP014582.1|WP_003811061.1|3093416_3094700_-|TRAP-transporter-large-permease	gnl|CDD|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	8.16313e-87
NZ_AP014582.1|WP_003811072.1|3085640_3089357_+|virulence-factors-two-component-system-sensor-histidine-kinase-BvgS	gnl|CDD|182169	PRK09959, PRK09959, acid-sensing system histidine kinase EvgS.	1.19298e-146
NZ_AP014582.1|WP_003811054.1|3096818_3097727_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	8.89176e-42
NZ_AP014582.1|WP_003811093.1|3061529_3062828_+|TRAP-transporter-large-permease-subunit	gnl|CDD|129868	TIGR00786, TRAP_transporter_permease_protein_SiaT, TRAP transporter, DctM subunit. The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family (TC 2.A.56)- DctM subunit TRAP-T family permeases generally consist of three components, and these systems have so far been found in Gram-negative bacteria, Gram-postive bacteria and archaea. Only one member of the family has been both sequenced and functionally characterized. This system is the DctPQM system of Rhodobacter capsulatus (Forward et al., 1997). DctP is a periplasmic dicarboxylate (malate, fumarate, succinate) binding receptor that is biochemically well-characterized. DctQ is an integral cytoplasmic membrane protein with 4 putative transmembrane a-helical spanners (TMSs). DctM is a second integral cytoplasmic membrane protein with 12 putative TMSs. These proteins have been shown to be both necessary and sufficient for the proton motive force-dependent uptake of dicarboxylates into R. capsulatus. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	3.23324e-98
NZ_AP014582.1|WP_138142578.1|3071431_3072166_-|molecular-chaperone-FimB	gnl|CDD|225663	COG3121, FimC, P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion].	2.05728e-76

Protein sequences

>NZ_AP014582.1|WP_003811078.1|3072415_3073021_-|fimbrial-protein
MNLKFAGIALGLTACALTYQHQVFAADGTLVITGAITDTTCKINGAEPPTNIAVQLPTISRTALKDVGSTAGGTVFDVKLTECPQALNGQQVGLFFEPGGTVDYTSGNLFAYRADSQGVEQVPQTKADNVQFQLANLDGSAIHLGRNKGAQAAQTFLVSQTAGSSTYGTTLRYLARYIRSGAGSIVAGNLRSQVGFSVMYP
>NZ_AP014582.1|WP_138142578.1|3071431_3072166_-|molecular-chaperone-FimB
MARWRRRLGVAALGAAMLASLAPAARASLVITGTRVIYNAGSPETTVKMSNEGQAPALMQAWIDDGNAEAKPDEVQVPFFLTPPLARVDPGKGQTLRIFFNGYPDGKTLPSDRESVFWLNVLEVPPKATPEEGHGVLQLTIRSRLKLFYRPKGLPGNPLTAAADLTFKRKANGVLEVHNPTPYYVNLQKLEVGENGAHGSKTPWMLAPLSSDELRLKGTGAKSVQYWAIDDFGGVTPYQAAIAD
>NZ_AP014582.1|WP_015063873.1|3068747_3071369_-|fimbrial-biogenesis-outer-membrane-usher-protein
MKQIPLILAMSLAFAAAAKGESAPDMQAAVNFDSAMLWGGANGADLSRFNYSNALRPGNYIVDIYANNYPLIRQQVRFVAAQTSGQGLKTAPAVACFTYGQLEAMQVRLRALDPALVADLKSSGRCEVLGKLFPDSRESFDFGENRLEVSIPQAYTINRFRRDISPDEWDSGITAFRLGYQYNYADYIGGLRAGRRLDLNLYSGFNFKGWYLRNSSTLGWGQGRFTRRSQRTSLQTDIPSWRARLVFGDVFSSGEYFAPYSMRGMLVGSDTAMLPYSERLYRPTIRGVARTRANVKVYQAGVLVFQDAVPPGPFAIDDYSPASYGGDLRVVVTEANGAVQTFTVPYASAVRLILPGQTQWSFSAGRYRNYRNDGQDRPWVTQLTGRHGVADGVNLYGGLLIAQAYQAGLAGLSWNTPWGAMAADATLSRSQLSTTGNANGSSLRFSYSKTLSGTNTAIRLATLRYSSSGFWNFADAVNAGPAETNGRNGRFGLYSLLGRERPRGDFSVTLSQPLGGYGSLYVSALRRTYWGSSRVDQQTQLGYSTQVGRVGVNLDVSRTENRRSTEHQVMLNLSIPLYGATSSGVVTGSLARTGSAPVQQSVNYSGMSGERDQYTYGLGVQRAGTSAQYALNGSWSGTYGEVSGQLTHGRSYSQYQINGSGGLVAHAGGVTFGQYQAGTIGLIQAEAAAGAKVVNTRNAAVDRSGYGLVSLTPYSLNEVELSPQDLPLDVQLESTVEQVIPRAGAVVALRFPTRHDVAAMLVAEPGSEGALVFGTEVRDGAGKVVGVAGQGASALVRGVSASGTLEVTRADGSICRATYDLKSAGQAVHGLPRIALACAPQGGGERGARAAVQAVAQPAPISISGKDHEPDIR
>NZ_AP014582.1|WP_172452891.1|3067636_3068767_-|fimbrial-protein
MSQIFADRRAAVPARVISFCGAALAIWAGLAVQPAMAVDPPVDCGRALGLHFWSSTSLISDQTPDGTLIGKPVVGRSLLSKSCEVPDDIKDELSDKHDGEPVDIVLELGSSYKIRPQSYGHPGIVVDLPSGSTEETGIAIYIDFGSSPMQKVGERQWLYPQKGEVLFDALAINGDNAEVRYQAIKVGPLKRPRKLVLSQFPNLFTYKWVFMRGTSQERVLATGTISTDVATSTIDLKTCRYTSQTVSLPTIQRSALTGVGTTLGTTDFQMPFWCYGRPRVSVYMSAANMQTGVDGVALPATGQAAGMASGVGVQLINGKTQQPVKLGLQGKIALPEAQQTESATFSLPMKAQYYQTSTSTSAGKLSVTYAVTLNYD
>NZ_AP014582.1|WP_033452387.1|3065892_3067644_-|filamentous-hemagglutinin-transporter-protein-FhaC
MTDATNRFRPGLVVRALVRAGLLFAVAACAQAQLLPGARDLNRIDDRQRKEQLQRDIERALTRPPVELNPQSEAASPARKPDATSGHTVTVHAVDLDFGVEGRLFDPTPLVQDYLNRPLDNEQLFLLVKALSAALYDRGYATSIVTFVPPGVVDGVLKLKVEWGRIKGWLIDGKPLERTRDRMMVFSAMPGWQDKVLNVFDIDQAIYNINNGGKTGNITIVPADEYGYSYLDLQLQRRALPRVSLGMDNSGPGTPENGRYKYNASVTANDLLGLNDTLGLYIGNRYYRDAGHDAERNYDLMYSVPLGRTRLDLQTGYSTYRNLLKTRYGQYQSAGNSRSFGLKATRLLYRDTRSQFSVYGGLKLRQNKNYLAGTRLDVSSKHYSDVTVGMQYSTQRGANAYFGDLSFTRGVGINNGKYAAYDERGPQGNVSRLNGSLAWTRYMALADQPLQWTSQLGFQYSRQQLLNSYQITVGDEYTVRGYNLRTSQSGDSGVYLSNTLTVPVQFSLFGKQASMAPFAGVDVGALKSNHPDARTIRMAGLAAGVRFDLPYARLSFTYSKPVGAQPGGAPRAPVWYINAGLSF
>NZ_AP014582.1|WP_033452384.1|3064565_3065867_+|TRAP-transporter-large-permease-subunit
MNEILIVTLLVVSIFALLGCGVWVGLTLAGTAWIGMEVLSSRPAGDAMAVTIWGASSSWTLTALPLFLWMGEILFRTRLSEDLFKGLAPWLNRLPGRLLHTNVIGCAIFAAVSGSSAATCATVGKMTIPELTRRGYPEDKILGTLSGAGTLGLLIPPSIIMIVYGVAADVSIAKLFIAGIFPGLLLALLFMGYIAWWAIRHPGAVPAADPGISFMQKLKQSRHLIPVLLLIGAVLGSIYTGIATATEAAAVGVVGALILSALQGSLTRASFMTSLLGATRLYCMIALILAGAQFLTLAMGYIGLPRALAEWIGGLGLSQFGLIMALMVFFIVLGCFLDGISIVVLTMGVLLPTVQAAGIDLIWFGIFIVFVVEMAQITPPVGFNLFVLAGMSGRELPYIARASLPMFFLMIVAVLLLYYLPGIATWLPQHMTL
>NZ_AP014582.1|WP_003811089.1|3064072_3064573_+|TRAP-transporter-small-permease
MRRFLDRLYGAAGLLAGLCTIGVLVSVLAAIIARQVGLNIPGTDAYAGYFMAAAGFLALASTFKHGEHIRVTLLLNALSAPGHRRLDIFALCVGAILAAAFAWFSVKLAHDSWLFNDISTANDATPLWIPQLTMAAGTILFFIALLDELVRRVRGQGFAKSQQIHE
>NZ_AP014582.1|WP_010930616.1|3063091_3064066_+|TRAP-transporter-substrate-binding-protein
MYKKLSLLAGTIVLAFGAGAQAQTKWDLPTAYPASNLHVENLTQFVKDVDSLSGGKLKITLHNNASLYKAPEIKRAVQGNQAQIGEILLTNFANEDPVYELDGLPFLATGYDASFKLYQAQKPFLEKKLASQGMMLLYSVAWPPQGIFANRDIKQVSDMKGLKWRAYSPVTAKIAELVGAQPVTVQQAELAQAMATGVIDSYMSSGSTGFDTKTYEYIKKFYDTEAWLPKNAVLVNKKAFDALDPATQQALKKAGAQAEERGWKLSQEKNSWYKEQLAKNGMAIIAPTAELKSGLTEVGKRMLDDWLKKAGADGQAMIDAYRKQ
>NZ_AP014582.1|WP_003811093.1|3061529_3062828_+|TRAP-transporter-large-permease-subunit
MGELAQSLVLIASLLLLLAAGVWVSLALVASGLVALLLFTDAPAGIIFATKSWDASANWALTALPLFIWMGEILYRTRLAEDMFSGLGPWVRRLPGRLVHVNVLGCGIFAAVSGSSAATAATIGRISLPELKARGYDDGLAIGSLAGAGTLGLLIPPSIVMIVYGVAAQVSLIKLFIAGILPGLLLMALFSGYIGVWSLRNPARVPPREPAVPWLTMLARLRLLLPVVALIAGVIGSIYAGIATATEAATIGVIGALAIAAWGKSLNRRSFIDSLMGATRTSCMISFILLGAAYLTSAMSFTGLPANLAEWISSLGLSQYGLIAVLTVFFILMGAFLDGISIVVLTTAVLMPAIQAADIDPIWFGIYLILVVEMAQITPPVGFNLFVIQGITGRNLFELVRMAFPFFLLLVLATAIITIFPAIVTALPLAMR
>NZ_AP014582.1|WP_003811094.1|3061045_3061537_+|TRAP-transporter-small-permease
MPILDRIAVASGAVAALFLALIGAIVAAQIASRLLGMQIPAADDFAAWSMAASVFLALPYAMLRGDHIRVTLLLQFLPKTAHRPYELAATALGLALSAWAAWQAAGFVHESFAYDEVAQGMLRVPLWIPQICMPIGLALLTLMLARRLAMVARGRQPEETAHG
>NZ_AP014582.1|WP_010930609.1|3085002_3085632_+|virulence-factors-two-component-system-response-regulator-BvgA
MYNKVLIIDDHPVLRFAVRVLMEKEGFEVIGETDNGIDGLKIAREKIPNLVVLDIGIPKLDGLEVIARLQSLGLPLRVLVLTGQPPSLFARRCLNSGAAGFVCKHENLHEVINAAKAVMAGYTYFPSTTLSEMRMGDNAKSDSTLISVLSNRELTVLQLLAQGMSNKDIADSMFLSNKTVSTYKTRLLQKLNATSLVELIDLAKRNNLA
>NZ_AP014582.1|WP_003811072.1|3085640_3089357_+|virulence-factors-two-component-system-sensor-histidine-kinase-BvgS
MPAPHRLYPRSLICLAQALLAWALLAWAPAQASQELTLVGKAAVPDVEITLDGDDWRWLARKRVLTLGVYAPDIPPFDVTYDERYEGLTADYMAIIAHNLGVQAKVLRYPTREQAVGALESGQIDLIGTVNGIEGRLQSLRLSVPYAADHPVLVMPIGARRAPPADLAGQRLAVDANYLPRETLQQAYPQATLHYFPSSEQALAAVAYGQADVFIGDALTTSHLVSQSYFNDVRVVAPAQIVTGGESFGVRADNTRLLRVVNAVLEAIPASERRSLIYRWGLGSSISLDFARPAYSAREQQWMANHPVVKVAVLNLFAPFTLFRTDEQFGGISAAVLQLLQLRTGLDFQIIGVDTVEELIAKLRSGEADMAGALFVNAARESVLSFSRPYVRNGLVIVTRQDPAAPADADHLDGRTIAMVRNSAAIPLLQQRYPQAKVVTADNPTEAMLLVADGQADAVVQTQISASYYVNRYFAGKLRIASALDLPPAEIALATARGQTELISILNKALYSISNDELASIVSRWRGSDGDPRTWYAYRNEIYLLIGLGLLSALLFLSWIVYLRRQIRQRKRAERALNDQLEFMRVLIDGTPNPIYVRDKEGRMLLCNDAYLDTFGVTADAVLGKTIPEANVVGDPALAREMHEFLLTRMAAEREPRFEDRDVTLHGRTRHVYQWTVPYGDSLGELKGIIGGWIDITERAELLRELHDAKESADAANRAKTTFLATMSHEIRTPMNAIIGMLELALLRPADQEPDRQSIQVAYDSARSLLELIGDILDIAKIEAGKFDLAPVRTALRALPEGAIRVFDGLARQKGIELVLKTDIVGVDDVLIDPLRMKQVLSNLVGNAIKFTTEGQVVLTVTARPDGEAAHVQFSVSDTGCGISEADQRQLFKPFSQVGGSAEAGPAPGTGLGLSISRRLVELMGGTLVMRSAPGVGTTVSVDLRLTMVEKSAQATPPAAAAQATPSKPQVSLRVLVVDDHKPNLMLLRQQLDYLGQRVVAADSGEAALALWHEHAFDVVITDCNMPGINGYELARRIRAAEAAPGYGRTRCILFGFTASAQMDEAQRCRAAGMDDCLFKPIGVDALRQRLNEAAARAALPTPPSPQAAAPATHDATPAAFSAESILALTQNDEALIRQLLEEVIRTNRADVDQLQKLHQQADWPKVSDMAHRLAGGARVVDAKAMIDTALALEKKAQGQAGPSPEIDGMVRTLAAQSAALETQLRAWLEQRPHQGQP
>NZ_AP014582.1|WP_003811069.1|3089403_3090279_-|EAL-domain-containing-protein
MIHWTNSARSSFEASLSPSRRTLRARLAPVEGPTVAELRAALKRDEFIPAFQPVVDAGTGSLFGVATTIQWAHRHWGLVPEHCYMAALVRDNLHIALAQQLLAQVFDLAAAMRRGNRHVGLFIQPEPICLMSRSYSDDVLRNLDHRGLPPFALTLAVSPSLLQSPYGQQSLHSLRRLHRAGCNLVLTVSTFDAESPPHLDALEICGIALMPELMYALRQGGRAGEACRAIAQQASAQRIPVMATGVVDEAMAQAADLLPCRYLLGDHVAPPMTGQRFLYWYYRREMPPNYP
>NZ_AP014582.1|WP_010930607.1|3090412_3091207_-|putative-hydro-lyase
MTILSLAGAGHQARLDARGGMLTGPTANLAPGHVQANLAILPQAVAGDFLRFCQRNPKPCPLLAVSEPGDPSLPELGLDIDIRTDVPRYRVWRDGKLVDEPLDVRGLWRDDLVAFLIGCSFSFEEAMLENGLPVRHIEQGCNVPMYRTNIATHPAGPFSGPLVVSMRPLKAADAIRAIQVTSRFPSVHGAPVHLGDPALIGIADLGRPDYGDAVEIRAGEIPVFWACGVTPQSVVAAVRPEFCITHAPGHMLVTDLLNSRLAAF
>NZ_AP014582.1|WP_033452391.1|3091264_3092614_-|amidase
MLPTLTQQSLALQEGRDTSSGLTQAALARAADPAGEGARVFTRVYAEQARAEARAADALRGAGVTRSAIDGLPLSIKDLFDVAGETTMAGSVARQDEPAAVRDAVVVRRLRAAGAVIVGRTNMTEFAYSGLGLNPHYGTPRNPWDRATGRIPGGSSSGAAVSVTDGMASGAIGSDTGGSVRIPAALCGLAGFKPSAQRVSMQGVLPLSANLDSIGPLAPSVRCCATLDAILAGGDDADIPAPAALRGLRLAVPTTLALDGLDAHVSATFAATLAKLAEAGACIDEIAVPEFAQLADINSKGGFTAAEAWAWHRDLIERAADRYDPRVVARIRRGADMSAADYIDLLAARQAWRARVEARIAGYDALVLPTVPVVAPAIADLEASDALFGSTNLLILRNPTLINFLDGSALSLPCHEAGTAPVGLMVAAANGSDRRVLAIGMAIEDLLGG
>NZ_AP014582.1|WP_003811063.1|3092674_3093394_-|DUF2848-domain-containing-protein
MAAARFTARYQMKIAFQVQADGATRTVETEIRNLVVAGWAGRDRAAIEHHIEELAELGVPRPSSVPLYYRIAENQLSQAGRVQAVGPDSSGEAETFVFSVGGELYVSLASDHTDRKLEAHSVALSKQVCVKPVASDAWRHADVAEYWDELVLRSYIVENGAEVLYQEGTLASLRTPQDLIAGYTQGQASLPEGTGMTCGTVAAIGGIRASTTFIMELHDPRRQRTLRHRYDVEVLPEIA
>NZ_AP014582.1|WP_003811061.1|3093416_3094700_-|TRAP-transporter-large-permease
MIATALILLLVLIGISIPVGAALGVLGLILDPLYSMLPLTRAIGEVTWSANNEFLLVAIPLFIMLGEVLLRAGFAERMYAAMSLWLSWLPGGLMHANIGASTLFSATSGSSVATAATVGTVAIPQIKKYGYNEPLFLGSLAAGGTLGILIPPSINLVIYGVLTNSSVPKLYLAGIIPGFAMAALFMMTVVVACVAKPSWGGHRIQASWAQRIASLVHLGPPMAIFFLVVGSIYAGLATPTEAAALGVLGALILAAWFRRLTWTMLREAIEGTMRSTAMIMLIVLAASFLNFVMSATGLTDALVQSITGLGLSPGWMLLIVVIFYLVLGCFMETLSMMITTIPIVAPIMIALGYDPIWLGILIIVLVEAALITPPVGLNLFVVQSLRKSGSMTAVINGALPFVLAMFVMLALLAFFPDLALWLPRVFG
>NZ_AP014582.1|WP_003811059.1|3094696_3095317_-|TRAP-transporter-small-permease
MTRSEHFRALGGLLRRAESLSRLAVWVGGALTIASVLLISFDVLARKFFGFTTGGADELSSYAFAISTSWALAFATLQRANVRVDVVYQYLPVRVSAVLDWIALVALGVFMVFMTYYAYEVVQTSWAQKSAANTPLATPLWIPQGLWALGLAWMCVTVALMLVRASAALVTGDLDLVKEICGVRSAQEEAEEEAAAGERMVKGASA
>NZ_AP014582.1|WP_003811054.1|3096818_3097727_-|LysR-family-transcriptional-regulator
MIDLKHIETFFWVSTLGSFRAAAEKLNTTQPAISQRIASLEADLGVRLFERDARGVSLTGKGQELLSHAERMLQMRHDLMQAAREQNVMSGTVRIGVAETIVQTWLPALIEHVHAAYPALVLQIEVDTTHVLRGQLMARQIDVAFLMGPILEARMENIPLCAYPLAWVASPLLELGPEPLTLERIGTLPVITYPSSSEPYRQVRDMLTRAGVAAPRMYGSASLAMVVRMTKDGIGTSVIAPVFLDEELARGELRLLNVQADPLPDLSFTASWVQGPDSHAARAIALLAQRTAAEHGGAIGAG
>NZ_AP014582.1|WP_003811052.1|3097830_3098793_+|DMT-family-transporter
MHRRQSGLAARPPASTTPTPFTARPLIGVALLILSMWTLSGLDASGKWVMAAGVPLLVLCWVRYLVHLVLVLTLVLPARGLRILRATRPREQIVRGAAMFCATLLFFTTLSYLPQAEATAINFLAPLIVLSIAPWVLKEPPRLSRWVAAGVAFLGVLIVIRPDGGLHPLGVMFGLLTACCFAAQYIATRKVAGDDPYTSLIWSGAVGALCLTAALPFILPPAMPVLRELSLGNWLLLLSTGVSGALGHLLQIGAYRNAAASTLAPFVYLQIVSATTIGWLFWGHFPDAITWLGIAIICASGSVIGVLEWRRGRRLAPAAT

Crispr_ID: NZ_AP014582_6

• CRISPR_ID: NZ_AP014582_6
• CRISPR_location: 3313259-3313356
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP014582_6

Consensus_repeat	Method
GTGCCTGTCCCGGCGGGGACAGGCACCC	CRISPRCasFinder

spacers of NZ_AP014582_6

>6.1|3313287|42|NZ_AP014582|CRISPRCasFinder
AGCCGCAGATGTCAGTCCCCATGCCGCTGGCGCATGACGGCG

CRISPR arrays and Neighbor proteins around NZ_AP014582_6

CRISPR arrays

The CRISPR arrays of NZ_AP014582_6

>merge|NZ_AP014582|6|3313259-3313356|CRISPRCasFinder
GTGCCTGTCCCGGCGGGGACAGGCACCCAGCCGCAGATGTCAGTCCCCATGCCGCTGGCGCATGACGGCGTGCCTGTCCCCGGCGGGGACAGGCACCC

>NZ_AP014582|6|6|3313259-3313356|CRISPRCasFinder
GTGCCTGTCCCGGCGGGGACAGGCACCC	AGCCGCAGATGTCAGTCCCCATGCCGCTGGCGCATGACGGCG
TGCCTGTCCCCGGCGGGGACAGGCACCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014582.1|WP_003810621.1|3314797_3316054_-|D-amino-acid-dehydrogenase	unknown	unknown	gnl|CDD|234819
NZ_AP014582.1|WP_033452424.1|3301441_3303019_-|lipoprotein	unknown	unknown	gnl|CDD|274177
NZ_AP014582.1|WP_161780343.1|3310409_3310769_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP014582.1|WP_003810609.1|3320760_3321978_-|four-carbon-acid-sugar-kinase-family-protein	unknown	unknown	gnl|CDD|377757
NZ_AP014582.1|WP_033452426.1|3303015_3303786_-|TcpQ-domain-containing-protein	unknown	unknown	gnl|CDD|132874
NZ_AP014582.1|WP_042144694.1|3312234_3313185_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176131
NZ_AP014582.1|WP_003810619.1|3316249_3317296_-|CDP-6-deoxy-delta-3,4-glucoseen-reductase	unknown	unknown	gnl|CDD|181058
NZ_AP014582.1|WP_004568554.1|3310761_3312138_-|DUF1446-domain-containing-protein	unknown	unknown	gnl|CDD|377804
NZ_AP014582.1|WP_003810615.1|3317852_3318725_-|MOSC-N-terminal-beta-barrel-domain-containing-protein	unknown	unknown	gnl|CDD|225758
NZ_AP014582.1|WP_033452429.1|3306942_3307773_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NZ_AP014582.1|WP_003810611.1|3319708_3320764_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl|CDD|273137
NZ_AP014582.1|WP_003810641.1|3305315_3306950_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NZ_AP014582.1|WP_003810643.1|3303963_3305319_-|amidase	unknown	unknown	gnl|CDD|223232
NZ_AP014582.1|WP_003810604.1|3321978_3323001_-|2-keto-3-deoxygluconate-permease	unknown	unknown	gnl|CDD|235384
NZ_AP014582.1|WP_003810603.1|3323250_3324177_-|ectoine-hydroxylase	unknown	unknown	gnl|CDD|131461
NZ_AP014582.1|WP_003810623.1|3313455_3314793_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|182876
NZ_AP014582.1|WP_003810637.1|3307790_3308735_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NZ_AP014582.1|WP_010926763.1|3308787_3310362_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173867
NZ_AP014582.1|WP_010926765.1|3318801_3319704_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_AP014582.1|WP_003810617.1|3317353_3317722_-|aspartate-1-decarboxylase	unknown	unknown	gnl|CDD|180090

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP014582.1|WP_003810611.1|3319708_3320764_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl|CDD|273137	TIGR00557, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase. This model represents PdxA, an NAD+-dependent 4-hydroxythreonine 4-phosphate dehydrogenase (EC 1.1.1.262) active in pyridoxal phosphate biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	4.07591e-117
NZ_AP014582.1|WP_033452424.1|3301441_3303019_-|lipoprotein	gnl|CDD|274177	TIGR02520, putative_Type_IV_pilus_protein, type IVB pilus formation outer membrane protein, R64 PilN family. Several related protein families encode outer membrane pore proteins for type II secretion, type III secretion, and type IV pilus formation. This protein family appears to encode a secretin for pilus formation, although it is quite different from PilQ. Members include the PilN lipoprotein of the plasmid R64 thin pilus, a type IV pilus. Scoring between the trusted and noise cutoffs are examples of bundle-forming pilus B (bfpB). [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking].	7.34755e-54
NZ_AP014582.1|WP_033452429.1|3306942_3307773_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.52051e-85
NZ_AP014582.1|WP_003810609.1|3320760_3321978_-|four-carbon-acid-sugar-kinase-family-protein	gnl|CDD|377757	pfam07005, DUF1537, Putative sugar-binding N-terminal domain. This conserved region is found in proteins of unknown function in a range of Proteobacteria as well as the Gram-positive Oceanobacillus iheyensis. Structural analysis of the whole protein indicates the N- and C-termini interacting to produce an interacting surface into which a threonate-ADPcomplex is bound, suggesting that a sugar binding site is on the N-terminal domain here, and a nucleotide binding site is in the C-terminal domain (manuscript in preparation). There is a critical motif, DDXTG, at approximately residues 22-25.	1.20657e-54
NZ_AP014582.1|WP_010926763.1|3308787_3310362_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173867	cd08502, PBP2_NikA_DppA_OppA_like_16, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_AP014582.1|WP_033452426.1|3303015_3303786_-|TcpQ-domain-containing-protein	gnl|CDD|132874	cd06911, VirB9_CagX_TrbG, VirB9/CagX/TrbG, a component of the type IV secretion system. VirB9 is a component of the type IV secretion system, which is employed by pathogenic bacteria to export virulence proteins directly from the bacterial cytoplasm into the host cell. Unlike the more common type III secretion system, type IV systems evolved from the conjugative apparatus, which is used to transfer DNA between cells. VirB9 was initially identified as an essential virulence gene on the Agrobacterium tumefaciens Ti plasmid. In the pilin-like conjugative structure, VirB9 appears to form a stabilizing complex in the outer membrane, by interacting with the lipoprotein VirB7. The heterodimer has been shown to stabilize other components of the type IV system. This alignment model spans the C-terminal domain of VirB9. CagX is a component of the Helicobacter pylori cag PAI-encoded type IV secretion system. Some other members of this family are involved in conjugal transfer to T-DNA of plant cells.	5.85631e-30
NZ_AP014582.1|WP_003810619.1|3316249_3317296_-|CDP-6-deoxy-delta-3,4-glucoseen-reductase	gnl|CDD|181058	PRK07609, PRK07609, CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated.	0
NZ_AP014582.1|WP_003810615.1|3317852_3318725_-|MOSC-N-terminal-beta-barrel-domain-containing-protein	gnl|CDD|225758	COG3217, COG3217, Uncharacterized Fe-S protein [General function prediction only].	6.93466e-61
NZ_AP014582.1|WP_003810621.1|3314797_3316054_-|D-amino-acid-dehydrogenase	gnl|CDD|234819	PRK00711, PRK00711, D-amino acid dehydrogenase.	0
NZ_AP014582.1|WP_003810617.1|3317353_3317722_-|aspartate-1-decarboxylase	gnl|CDD|180090	PRK05449, PRK05449, aspartate alpha-decarboxylase; Provisional.	1.84176e-73
NZ_AP014582.1|WP_003810641.1|3305315_3306950_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NZ_AP014582.1|WP_003810643.1|3303963_3305319_-|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	6.98538e-115
NZ_AP014582.1|WP_003810604.1|3321978_3323001_-|2-keto-3-deoxygluconate-permease	gnl|CDD|235384	PRK05274, PRK05274, 2-keto-3-deoxygluconate permease; Provisional.	9.56796e-132
NZ_AP014582.1|WP_003810603.1|3323250_3324177_-|ectoine-hydroxylase	gnl|CDD|131461	TIGR02408, putative_L-proline_4-hydroxylase, ectoine hydroxylase. Both ectoine and hydroxyectoine are compatible solvents that serve as protectants against osmotic and thermal stresses. A number of genomes synthesize ectoine. This enzyme allows conversion of ectoine to hydroxyectoine, which may be more effective for some purposes, and is found in a subset of ectoine-producing organisms.	0
NZ_AP014582.1|WP_003810623.1|3313455_3314793_-|extracellular-solute-binding-protein	gnl|CDD|182876	PRK10974, PRK10974, sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB.	1.31172e-74
NZ_AP014582.1|WP_003810637.1|3307790_3308735_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.42336e-123
NZ_AP014582.1|WP_004568554.1|3310761_3312138_-|DUF1446-domain-containing-protein	gnl|CDD|377804	pfam07287, AtuA, Acyclic terpene utilisation family protein AtuA. This family consists of several bacterial and plant proteins of around 400 residues in length. One member of this family has been characterized in Pseudomonas citronellolis as AtuA, a member of a gene cluster that is essential for the acyclic terpene utilisation (Atu) pathway.	2.30072e-160
NZ_AP014582.1|WP_010926765.1|3318801_3319704_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	2.15288e-54
NZ_AP014582.1|WP_042144694.1|3312234_3313185_+|LysR-family-transcriptional-regulator	gnl|CDD|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.63053e-66

Protein sequences

>NZ_AP014582.1|WP_042144694.1|3312234_3313185_+|LysR-family-transcriptional-regulator
MRPQADLSTRQLRAFVMLADLRHFTKAAQACHLSQPAFSALIQSLEATLAMQLFDRSTRRVVLTQEGELFEPLARRLLADLGHAMTHIASFVELRRGRVHVAALPSRAAGWLPKVLHEFHAEHPDIELMLSDVLSDECIELVRSGQADFALASRGIRASDPAVLHARELCSDTFHLICRKDHPLAREPRLTLKHLAPWPFIHLTRNSSVRQTVEAALRPQVAKTILEVAQLATVAGMIEAGLGISVVPTFTLYQFERPGLLIRPISLPGLTRQIYIVRRQEERLSIAAQALYDLVVAKLGTPAAAKPRRRRTEKGR
>NZ_AP014582.1|WP_004568554.1|3310761_3312138_-|DUF1446-domain-containing-protein
MRSLPSLLIGCAAGFSGDRVDAAGPVVDTLIARLGGVPANGRAFLIFETLAERTLALAQLRKRADAQAGYEPLLEDMLGPVLARCLAHGIRIVSNFGAANPEGAARHILRMAARLGLRKPRIAVVKGDDVSGAQHAGMLAEYLGEQYDPSSIVSANAYLGSEQIRDALDHGAEIVVCGRVADPSLTVGPAMSYFGWQADDWDRIGRATMAGHLLECGAQVCGGYYADPGYKDVPGLEQVGFPVAEIDEDGHCIIGKSDGTGGLVDEATVIEQLLYEVHDPAGYLTPDVVADISQAEVRRVADNQVRLTGVRGHPRPAAYKVNVCLEGGWLAEGEISYAGPRAEARARLAAEVVCKRLADLRIRTDLIGRVSIFGDDAGRLLAGAPAGDGEDVRLRLAAHAVTRQDAMRLTREVTALYCCGPAGGGGVRTTLTPRLDMVSCLLPRDLVRAGFEMVDADV
>NZ_AP014582.1|WP_161780343.1|3310409_3310769_-|hypothetical-protein
MSDVLVPLFRVAHARTGDKGDRSNISVIAWDRALYPLLVEQLTPEVVLAQFAHRRPAGAQRYLLPKLGAMNFVLDAVLDGGVNGALNLDAHGKALSYLILKTEIAVPSDLVCRLAGSPG
>NZ_AP014582.1|WP_010926763.1|3308787_3310362_-|ABC-transporter-substrate-binding-protein
MRYLKSTYAAVLLAIGTAVPHATTLAQEVKVAAEAPLRLLDPVGTTAYITRNHAYMVYDTLFALDAQLKPQPQMVSTWSVSPDKLVYRFTLRDGLKFHDGSPVTAADCVASIKRWAQRDLTGLRMMAAAKEITAKDDKTFEIVLEQPFGAVIEGLSKASSLPAFIMPKRIADAPASQAITEVIGSGPFRFVASEYRPGLQVVYERNTDYVPRSEPPSGLAGGKVVNVDRVVWLSLPDIQTEANALAKGEVDYVQTVYPDVVQTLQASKDVVIQKLASTTTPTLRLNWLQPPFNNQKVRQALLHAVSQRDYMDAQVGDPKAYRVCWAMFGCDSPLASTAGVVSQDDEADLNAAKALLKESGYKNEKAVVLHATDYPPTSAIAPFTAQILRSIGMKAEVQSMDWATFLTRRGKQDPVEKGGWSVAYGSWNTLDLMSPIANLNLDGRGKEGYAGWTESAEMESLRTQYAQATEPASRQQIAAKIQQLAYDQVFYIPLGTYSNYAARRSNVTPLLDAPVTVFWGISKN
>NZ_AP014582.1|WP_003810637.1|3307790_3308735_-|ABC-transporter-permease
MQILRLLFLRLASAIPVVLVVVTVVFLLVRLTGDPATILAGDMASPEVVASVRADLGLDRPLLGQYAQWLWDLLQGNLGTSIVTKQPVATLIGERLESTLVLSLSALVVTVLLAVPLGVLAAWRHNTLVDRVVMIYAVIGFSLPSFVVGYLLILMFSVWLGWLPVQGYVSITDDIWLAAQHLVLPTLALAIFYMSLISRVTRASVLEVLNEDFVRTAKAKGVPPLRILSQHVLRNAAIPIVTVIGIGLAFLISGVVITESVFNLPGLGRLTIDAVLSRDYPVVQGVILFFACVYILVNLLIDMLYVVIDPRIRY
>NZ_AP014582.1|WP_033452429.1|3306942_3307773_-|ABC-transporter-permease
MTSILRHNRLALLGGGVLLLMVAISVAASWIASMDPAMMQPRMRLTPPGEAFLLGTDALGRDVYSRVVHGSRMSLAIGALVVVITIAIGTLIGLVAGASRIMDRVLMRIMDGVMAIPGILLAVALVSLFGASLASVVIAIAVPEIPRVVRLVRSVVLSVREEPYVEAAVGLGVPYPKVVWRHILPNCFAPLIVQASYVFAAAILLEAVLGFLGVGFPPEIPTFGNILAEARPVFQRAPWATVAPGLLLAVTVLAVNLLGDGLRDSLDPKLARCAND
>NZ_AP014582.1|WP_003810641.1|3305315_3306950_-|ABC-transporter-ATP-binding-protein
MIENTPKQRVLEVSGLAIRAGARTLVQDVTLSLAQGEILCLVGESGSGKSLTASAVMGLLPGNLGVSAGSIRLDGEDLTAASPARMQALRGDRMAMVFQEPMTSLNPLMRVGRQIAEVLQVHRPDLGAGQVRARVLELMGDVHLPTPEALMDAFPHQLSGGQRQRIMIAMALALEPALIIADEPTTALDVTTQAQVLKLFRQLLAKHSSAVLFITHDFDVVRDIADHVAVMQLGRIVEQGPAGQVLDAPRHDYTRKLLAAVPSGVPKTQQNASSDELLSVSGLNLVYESRGLLGPARRTHAVADVGFTLKKGETLGVVGESGSGKSTLGRCITRAHAPTSGRIVFDGVDIAGLSGKALRAVRRRVQMVFQDPYRSLNPRRRILHALIEGPIESGVDRKAACARAAELMALVGLPADGLQRYPHQFSGGQRQRICIARALAMEPDLIVADEAVSALDVSVQAQVLELFEDLQKRLGFAMIFITHDLRVAAQVCDRIGVMQKGRLLELGPVRQVIHAPQHPYTRHLFDSLPGRVGQAAEPAMELQA
>NZ_AP014582.1|WP_003810643.1|3303963_3305319_-|amidase
MTSTDQHIARAGVAELARGIARGAFTPAEVTDVFLRRIQDLNPAIGAFVAVYEDEARHAARQATQALAQGQRLSPLHGIPFAVKDIVDVAGRFTTYGSRTGAGRQAGATAEYVRALLDAGMILLGKTHTVEFAFGGWGTNQRMGTPRNPLRADVPCATGGSSSGSGAAVGAQMVPFAVGTDTGGSIRIPSAFCGLTGMRPSMGRHSGAGVMSLSHTLDTIGPLARTVEDVQMLDDLLTGKTATDTAQPGSQAVARVRDARIGVLGAQWLGAIEPEVAHAYAQSLRAFEAMGATLVELALPFDREAFAQLTSTLIACEGLQFAGKYVHDPLSGMDEDVRARFLVGDRYDAAAYAELLGRRSAMIDTFTQAMAGVKALLMPTTPCVAQPLAGLEQSPYNPAVYTRMPAWLGCCALAVPNGSGAHGLPTSLQIVGLPESDRLVMSLGRAYQEYA
>NZ_AP014582.1|WP_033452426.1|3303015_3303786_-|TcpQ-domain-containing-protein
MVRSLSIVCLLAVLQACAGPRPAAVAAAWDEAPAGQYRFDWQLSGDPAVAPLQVFDDARRIWLQFAPGQPIPAIFAHGAGGERPVPYLRRDPYIVVDGAWPALSLRGGRYVARIQRSGAPIPAGAPVVRAEGPAPVPATPSAVAPAEAAEAAEAAPPAPRFRAAPPDLTLRAVLARWARAAGWTFEAEHWALDVDIPLAGKAELPGDFKTAVRALLAATELSERPAQPCFYANRVLRVVPLAQACDRTRAAAPGLT
>NZ_AP014582.1|WP_033452424.1|3301441_3303019_-|lipoprotein
MKARRLAMAGLSLALGGCSLSQQMQAMRDAATSLRARLLEGQQAVGRAGERPAREAAQDVARPWLAGRAQPLAREVLLPPALRADVDTTLLFAGKATLPVLAERLHRATGIAVRVHPDALLPRAAFLPRLAGPAELAAEPPAQAELRAGPRPLADTLDALAAQLYVHWRYHRGAIEFYRTETRVFDVRTLALAASAQARLGRAGSGETGSFDHASSTVLSADAGKALQAVRDRVAAFLTRAGVIAEIEAGGSTLAVTDTPEALARIEKYLQGENRALTRRVRLVFEELTVRTMAAAEGGIDWQAVYASARAAASYAMPGGAGAAGALGARVLAGPWRDARALIAALSTMGAVLRHRSIPMLTLNRRAVTHAVRTTFSYVDQVQRLSPTAAAPGGRDAVPGLAVQQKRETVGTFLTLLPEARDDGRILLSISYDNTIAQPLRTLTFGEGGQQVSLQQIAIDGSGIVQQVELLPGQPVILSGFDHSEDQYERHRLFPDAPLAAGGHDRTARERVTTVVMVTAQIDEG
>NZ_AP014582.1|WP_003810623.1|3313455_3314793_-|extracellular-solute-binding-protein
MKKLQMTGFARAMRASRRACVLGLAMAAMGVAQAADSVEIQVWHTLSGPNKAEFEKLAKQFNKEQGDVVVKLRDFGNQDDLKKEAVSAVKSKKGPNLVQLADNHSPEVVAEHKSILPLHQLLAKYPVKDLNWFLPSTTSFTRDGKGRLLAFPWMAEVPVMFYNTAYYKKAGLDPNKPARTWADLQAELLKLRDVANIDCPYATSDQVTVHLENLAPVNNQLYATLNNGLDVAKKGSPSMQFDTLYMRHVSLMVSWKRSLLLTAYSDDNKSDQLFAKGECAVLTTSSSALGQFLNTRSLSFGVAPLPYYDQVTKTGGRPFVSGSALWAMEGHPQAEEKATAKFLAWLSKPVIAAEWHQRTGYLPLTEAAFRASDVSFYNKVPGAQQLVELMRNPPAATSRGFRIANYERIEPVLNTQLTAAFDGKTPPVAALNNAASQARSLAAQR
>NZ_AP014582.1|WP_003810621.1|3314797_3316054_-|D-amino-acid-dehydrogenase
MKVAVLGSGIIGVSSAWWLSQAGHDVVVVDRCTGAAQETSLANGAQISVSYAEPWANPQAPFKLLKWMFQDDAPLLFRPQLDWRQWQWGLAFLRECLPSRLAPNIRAMVRMAEYSRATLQGMRAELGIQYDHLERGILNFYRDQREFETSQRAAGLMRDFGVERRVINADEVVAIEPALAPHRQTIVGGDYTPEDESGDVHLFAAALARRCEAAGVEFRFSTRVTRLLGEGGRVQGVELIEPDGRYGRLDADAFVVAMGSFSAQLVRPLGVPCMVYPAKGYSATFPVRPGALAPVVSLTDSSHKVVFSRLGERLRMAGTAELSGYSRGLNTGRCEAMTRLARELFPDALDFERVSYWSGLRPSTPSNVPLIGRTSVSNLYLNTGHGTLGWTMGVGSGRALADLLSGRRPEPEFPFLGL
>NZ_AP014582.1|WP_003810619.1|3316249_3317296_-|CDP-6-deoxy-delta-3,4-glucoseen-reductase
MSFQVTIEPSKHQFQAEAGQTVLDAALAAGIVLPYSCRTGACSTCKGKVVAGEVDAGPYPAQILSPEDLAQGYTLFCQAKPQSDLVVESTEVRLASDIQIRKLPSRVQTIERVAPDVAVLKLQLPASEQFRYYAGQYIEVILKDGKRRSYSMAGAPHTGSPLELHIRHMPGGLFTDHVFGAGDTQMKEREILRLEGPFGSFFLREDSDKPIVLLASGTGFAPVKAIVEHMIHNQIQRPAVLYWGGRRPRDLYHDALAQSWAGSLPGFRYVPVVSDALDEDGWSGRTGYVHEAVMQDLSDLSGYEVYACGTPLMVDAARREFSAQCGLPAEAFYADAFTSEADLAKATP
>NZ_AP014582.1|WP_003810617.1|3317353_3317722_-|aspartate-1-decarboxylase
MQRIMLRAKLHRVTVTEADLHYEGSCGIDEDLLDAAGMREFERIELYNVTNGERFDTYIIKAARGSGAISLNGAAARRAQVGDLLIICTYGPMSEEQSATHKPQVVLVDDANRVKEIRKFPA
>NZ_AP014582.1|WP_003810615.1|3317852_3318725_-|MOSC-N-terminal-beta-barrel-domain-containing-protein
MSTRIRSLHIYPVKSCAGIDLAESIVDRAGLAHDRRWMVTTAAGQFMTQRQYPQMARIRTALEDGMLVLRAPGMEDLRIPADGSELAERTQPVGVWRDTVIARAEHPRSAEWLSRFLGLPCRLLKIDLRADRSANPEWVDTWLERHPEWAEDFAGDHFFGFADGFPLLVANQSSLDELNERLAARGQAPVPMNRFRANIVVEGDWPAFEEDQTACIVAGGVRMAFVKPCTRCPMPNVDQVTAEVYDEPGLTLTTFRSLEIGVVFGQNAIVDRTAPAPLRVGDAVEIELDF
>NZ_AP014582.1|WP_010926765.1|3318801_3319704_-|GntR-family-transcriptional-regulator
MALSAIEPFALDRSGATPLHAQVADAIRNHIRDHRLTAGTVLPSEAALCHSFGVARSVVRQALGALVAEGLIRRDPGRAPVVAPPREHRRMVQRSAGLYEQFAGLGVALRTRVLACRPAEPPPEVAAFFGTTETLLLERLRSVDAQPLAYVRTWLPRAAIAGLAADHLQDASLHRVLAQRFGLRPGRGRNRIRAVAAEAALAQALDVAPGSPLLMLEGQGLDQDGHPLEWFTTWHRPENLVFDVDVGQERESVQPALTCGTAAVAPPAVAAPPSGALDAVEQSLLQALQAVRRARGDQQE
>NZ_AP014582.1|WP_003810611.1|3319708_3320764_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MTQDATPSRIPTLAVTLGDVAGIGPEITAKMLLGHDELRQRARLLVVGDAAVLAQAVQAVGGDPARVRVIATPAEATNQPGSIEVIQAGPSLAHVPPGQLSAEAGDGSVRYVTTACALARDGLIDGIVTAPLNKAAMHMAGHKWPGHTELLAHEFGVKTFSLVLSAGDLYIFHATTHVSLRQAIEDVNPQRMRAVLRLAGSFARALGRADHPVAVAGLNPHAGENGIFGTEDAEILAPAVAQANAEGILAAGPIPADALFPQAVRGKWKFVIACYHDQGHAPFKSVYGDDGVNITVGLPVVRVSVDHGTAFDIAGKGIAREDSLVLAAERAAQLAPGWHQVWETARSTTGG
>NZ_AP014582.1|WP_003810609.1|3320760_3321978_-|four-carbon-acid-sugar-kinase-family-protein
MGGPYIGIVADDLTGSGDTAVQFVRAGWATQLSVGGAEQALADPAVRQAEVLAVTTHSRPLAAADAAAVVRGEVERLRAAGVQRLYKKVDSTLRGAFKAEIDAARLAWGEDAIAVVCPAFPVTGRTVRQGVLYVGDRPVTETSAATDPVTPVTESHIPTLLGCAQLAAQAGETPAELARRIAAAAPVVVVDALDDADVQRLARAIGVLGQRAVPVGSGGLAAPLARVWAGGQAAGPVLVVVTSQHSAARQQAAALQQAGARTWAPTLAQLADDRNWAAWTAEVEAAEHGMPAVDALMLLAPEGRLAGLDADSVARRLGELAARLVLAHGAAGVVATGGDGASAVLAALQASGIALVDEVTGGVPLGTLTGGQAAGLPVVTKAGGFGEQDVLIRAAQAIRERRFTK
>NZ_AP014582.1|WP_003810604.1|3321978_3323001_-|2-keto-3-deoxygluconate-permease
MTTEVSRVPFYTTMMKVPGGLMLLPLILGSLLGTFAPDALAIGGFTTALFKNSALPLIALLIFATGTQVNMRTGGPILATAGTILLMKTLVPATLIILLGHFVGLDGVMGISILAMLAAFDNSNGGLWLAYTGQYGDSRDRGAYVASAVNDGPFFSLLFLGASGLADIPTIALVAALVPFLLGVVVGNLDIEWRNVLKPVPNIVIPFFAFALGTGINLGAVISGGMSGLVLGLLISPITGALVYFGYRYILRRGGKSGLGFAAGTTAGNAIATPAVVAAADPSFQPYVATATAQVAACVLISSILAPVLASYFLKRAGELKPVEQEPQDERAGQPAEVSL
>NZ_AP014582.1|WP_003810603.1|3323250_3324177_-|ectoine-hydroxylase
MISPAQDPYASRTDRSSAIIARQDPVVYGEGKFADALSADQVQSYERDGFLLLENLFSDEEVAALLAEVERMTRDPAIVRREEAITEPGSNAVRSIFMVHVLSPILGRLVRDPRLANAARQILGSEVYIHQSRANMKPGFKGKEFYWHSDFETWHVEDGMPSMRALSCSVLLTDNNETNGPLMLVPGSHRQFISCVGETPRDHYKQSLKKQEYGVPDPVSLQLLAEQGGISTMTGKAGSVVFFDCNTMHGSNSNISPWPRANVFMVYNSMENTLNPPKYGLNPRPEHIATRQAFKAVRPLDSLKLVER

Crispr_ID: NZ_AP014582_7

• CRISPR_ID: NZ_AP014582_7
• CRISPR_location: 3453473-3453546
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP014582_7

Consensus_repeat	Method
GGCGCCTGTCCCGGCGGGGACAG	CRISPRCasFinder

spacers of NZ_AP014582_7

>7.1|3453496|28|NZ_AP014582|CRISPRCasFinder
ATACCGTCTTGGCAGGCCAGCGGGACGG

CRISPR arrays and Neighbor proteins around NZ_AP014582_7

CRISPR arrays

The CRISPR arrays of NZ_AP014582_7

>merge|NZ_AP014582|7|3453473-3453546|CRISPRCasFinder
GGCGCCTGTCCCGGCGGGGACAGATACCGTCTTGGCAGGCCAGCGGGACGGGGTGCCTGTCCCGGCGGGGACAG

>NZ_AP014582|7|7|3453473-3453546|CRISPRCasFinder
GGCGCCTGTCCCGGCGGGGACAG	ATACCGTCTTGGCAGGCCAGCGGGACGG
GGTGCCTGTCCCGGCGGGGACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014582.1|WP_003810344.1|3461631_3462378_-|pyridoxine-5'-phosphate-synthase	unknown	unknown	gnl|CDD|235380
NZ_AP014582.1|WP_003810348.1|3459986_3461048_-|beta-N-acetylhexosaminidase	unknown	unknown	gnl|CDD|235417
NZ_AP014582.1|WP_003818550.1|3453696_3455019_-|isocitrate-lyase	unknown	unknown	gnl|CDD|237893
NZ_AP014582.1|WP_003810340.1|3463870_3467101_-|multidrug-efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|273335
NZ_AP014582.1|WP_010928200.1|3449438_3450092_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|273783
NZ_AP014582.1|WP_033447532.1|3458194_3460024_-|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl|CDD|234792
NZ_AP014582.1|WP_003810379.1|3445691_3445835_-|cbb3-type-cytochrome-oxidase-assembly-protein-CcoS	unknown	unknown	gnl|CDD|377073
NZ_AP014582.1|WP_172452889.1|3452618_3453341_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP014582.1|WP_003810358.1|3456165_3457419_-|MFS-transporter	unknown	unknown	gnl|CDD|340883
NZ_AP014582.1|WP_010926789.1|3445831_3446806_-|membrane-protein	unknown	unknown	gnl|CDD|319774
NZ_AP014582.1|WP_003810367.1|3451512_3451872_+|CidA/LrgA-family-protein	unknown	unknown	gnl|CDD|377131
NZ_AP014582.1|WP_003810369.1|3450088_3451525_+|dethiobiotin-synthase	unknown	unknown	gnl|CDD|379223
NZ_AP014582.1|WP_003810381.1|3444079_3445567_-|cytochrome-c-oxidase,-cbb3-type-subunit-I	unknown	unknown	gnl|CDD|237726
NZ_AP014582.1|WP_042144744.1|3462374_3463874_-|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl|CDD|182103
NZ_AP014582.1|WP_003810375.1|3446870_3448145_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl|CDD|235656
NZ_AP014582.1|WP_003810356.1|3457582_3458155_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl|CDD|182763
NZ_AP014582.1|WP_033449714.1|3448248_3449442_+|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl|CDD|273303
NZ_AP014582.1|WP_033447527.1|3455337_3456159_+|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl|CDD|236986
NZ_AP014582.1|WP_003810346.1|3461085_3461547_-|holo-ACP-synthase	unknown	unknown	gnl|CDD|234610
NZ_AP014582.1|WP_003810365.1|3451864_3452608_+|LrgB-family-protein	unknown	unknown	gnl|CDD|377236

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP014582.1|WP_003810344.1|3461631_3462378_-|pyridoxine-5'-phosphate-synthase	gnl|CDD|235380	PRK05265, PRK05265, pyridoxine 5'-phosphate synthase; Provisional.	5.79242e-145
NZ_AP014582.1|WP_003810348.1|3459986_3461048_-|beta-N-acetylhexosaminidase	gnl|CDD|235417	PRK05337, PRK05337, beta-hexosaminidase; Provisional.	0
NZ_AP014582.1|WP_003818550.1|3453696_3455019_-|isocitrate-lyase	gnl|CDD|237893	PRK15063, PRK15063, isocitrate lyase; Provisional.	0
NZ_AP014582.1|WP_003810340.1|3463870_3467101_-|multidrug-efflux-RND-transporter-permease-subunit	gnl|CDD|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NZ_AP014582.1|WP_010928200.1|3449438_3450092_+|alpha/beta-hydrolase	gnl|CDD|273783	TIGR01738, Pimeloyl-_methyl_ester_esterase, pimelyl-[acyl-carrier protein] methyl ester esterase. This CoA-binding enzyme is required for the production of pimeloyl-coenzyme A, the substrate of the BioF protein early in the biosynthesis of biotin. Its exact function is unknown, but is proposed in ref 2. This enzyme belongs to the alpha/beta hydrolase fold family (pfam00561). Members of this family are restricted to the Proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	4.76982e-07
NZ_AP014582.1|WP_033447532.1|3458194_3460024_-|excinuclease-ABC-subunit-UvrC	gnl|CDD|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NZ_AP014582.1|WP_003810379.1|3445691_3445835_-|cbb3-type-cytochrome-oxidase-assembly-protein-CcoS	gnl|CDD|377073	pfam03597, FixS, Cytochrome oxidase maturation protein cbb3-type.	1.64467e-12
NZ_AP014582.1|WP_003810358.1|3456165_3457419_-|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.57397e-25
NZ_AP014582.1|WP_010926789.1|3445831_3446806_-|membrane-protein	gnl|CDD|319774	cd02079, P-type_ATPase_HM, P-type heavy metal-transporting ATPase. Heavy metal-transporting ATPases (Type IB ATPases) transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. These ATPases include mammalian copper-transporting ATPases, ATP7A and ATP7B, Bacillus subtilis CadA which transports cadmium, zinc and cobalt out of the cell, Bacillus subtilis ZosA/PfeT which transports copper, and perhaps also zinc and ferrous iron, Archaeoglobus fulgidus CopA and CopB, Staphylococcus aureus plasmid pI258 CadA, a cadmium-efflux ATPase, and Escherichia coli ZntA which is selective for Pb(2+), Zn(2+), and Cd(2+). The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This family belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	3.27753e-20
NZ_AP014582.1|WP_003810367.1|3451512_3451872_+|CidA/LrgA-family-protein	gnl|CDD|377131	pfam03788, LrgA, LrgA family. This family is uncharacterized. It contains the protein LrgA that has been hypothesized to export murein hydrolases.	2.10855e-25
NZ_AP014582.1|WP_003810369.1|3450088_3451525_+|dethiobiotin-synthase	gnl|CDD|379223	pfam13500, AAA_26, AAA domain. This domain is found in a number of proteins involved in cofactor biosynthesis such as dethiobiotin synthase and cobyric acid synthase. This domain contains a P-loop motif.	3.91071e-66
NZ_AP014582.1|WP_003810381.1|3444079_3445567_-|cytochrome-c-oxidase,-cbb3-type-subunit-I	gnl|CDD|237726	PRK14488, PRK14488, cbb3-type cytochrome c oxidase subunit I; Provisional.	0
NZ_AP014582.1|WP_042144744.1|3462374_3463874_-|efflux-transporter-outer-membrane-subunit	gnl|CDD|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	7.79277e-112
NZ_AP014582.1|WP_003810375.1|3446870_3448145_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl|CDD|235656	PRK05964, PRK05964, adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional.	0
NZ_AP014582.1|WP_003810356.1|3457582_3458155_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl|CDD|182763	PRK10832, PRK10832, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.	3.46977e-48
NZ_AP014582.1|WP_033449714.1|3448248_3449442_+|8-amino-7-oxononanoate-synthase	gnl|CDD|273303	TIGR00858, Putative_8-amino-7-oxononanoate_synthase, 8-amino-7-oxononanoate synthase. 7-keto-8-aminopelargonic acid synthetase is an alternate name. This model represents 8-amino-7-oxononanoate synthase, the BioF protein of biotin biosynthesis. This model is based on a careful phylogenetic analysis to separate members of this family from 2-amino-3-ketobutyrate and other related pyridoxal phosphate-dependent enzymes. In several species, including Staphylococcus and Coxiella, a candidate 8-amino-7-oxononanoate synthase is confirmed by location in the midst of a biotin biosynthesis operon but scores below the trusted cutoff of this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	1.2202e-142
NZ_AP014582.1|WP_033447527.1|3455337_3456159_+|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl|CDD|236986	PRK11792, queF, 7-cyano-7-deazaguanine reductase; Provisional.	0
NZ_AP014582.1|WP_003810346.1|3461085_3461547_-|holo-ACP-synthase	gnl|CDD|234610	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional.	1.59551e-52
NZ_AP014582.1|WP_003810365.1|3451864_3452608_+|LrgB-family-protein	gnl|CDD|377236	pfam04172, LrgB, LrgB-like family. The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance.	1.36587e-69

Protein sequences

>NZ_AP014582.1|WP_172452889.1|3452618_3453341_-|hypothetical-protein
MACFMALVLARFGFGFCMLLAALVLLVAATLLATRLVGWAVRAFALERSQALASGVAIFVLVALALWGCHAVGEALYGAIGATALVGGAPHWLAGNSHVSAAALMGATTAAAMLAGGPAFWRWLRARRAAAAEQPAPRKAAPPKGAKPAARAAKAAAKTQIAPRGQRIPWLGWTAFFLLFIGAAVLAFAYIVAPIEAGASGLRLEHATRARPVYLAGLTLLGGGAFFLLAWLSRRRPPGD
>NZ_AP014582.1|WP_003810365.1|3451864_3452608_+|LrgB-family-protein
MPDFVNLWIYLSSTPLFGLTATLTVYLSAHAMYLRLGQVPLANPVLWSMVVLAAGLLAFGVPYPTYFAGAQFIHFLLGPAVVALAWPLWMRRAELRRRWARLLWAALFGGAVACASAVLLGWAVGLPRDIILSLAPKSVTAPVAMGLSETLGGIPALSAVFAALTGLVGALTGKYLFDLLGPVRGRQDWADRGFALGTVSHGIGAARAIQVNADAGAYAGLALGLQVILASLLIPVAFRLAAGLGGS
>NZ_AP014582.1|WP_003810367.1|3451512_3451872_+|CidA/LrgA-family-protein
MQALTGFTWLLALQALGEACSRLLHFPIPGPVTGMLLLLVALRWPLVREPVALAAQFLLSHLSLLFVPVGVGVMTHIALLAEYGLRMAAVIALSTLAGMAATYWALRVGRSAAPETDDA
>NZ_AP014582.1|WP_003810369.1|3450088_3451525_+|dethiobiotin-synthase
MSTRSTPTIGQRFDRAAARYETHAEVQRHAAEQLAERIAALPLPAEPRILEIGCGTGLLTRALARRLGRADWTITDIAPAMLAAQQAGPPPAGRVRHQLVDGEHPAGLPGGYDLICSSLAVQWFGDLDAGLARLAGLLAPGGLLAIATLAEHTFSEWRAAHQAHGLHAATPAYPPAERIGRTLAGLRGGITREAYRQRHPDALHFVRSLKAIGASAPAAGHAPLSPAAFRRVLAQFDRQGNHVTYDLAYGLWRKQAPGVFVTGTDTGVGKTLASAILARAWRAHYWKPLQTGVAEEPGDTETVAALAGLEPARLHPPAHVLQAPLSPWAAAPLEGVTLDAAAIAPPQVDGPLVVEGAGGLYVPIDERHMMIDLIARLGMPVVLAARSGLGTINHTLLSLHALRERRLPVLGVIMLGEPSAGNRHAIEHFGGVPVLAQIPRLARVDAEAVEAWAARIPPLADCLARRWPDTQETPACRP
>NZ_AP014582.1|WP_010928200.1|3449438_3450092_+|alpha/beta-hydrolase
MSAPRPLLRFEHGWAHDAGVWAPLRAALADWPQQAADAGYFGPAVEPPPDGAPVVAIGHSLGFLKILQSPAPGCIAYIAINGFARFAGGADYPPGVAPRLLERMLARLELDPAAVVDDFRRRAGSAPHAGTPRPEPLRHDLRRLREADERQALAASRLPLLALAGTADPIVAPALTRAQFGACAGLRWRDGGGHLLPTSDPDWCAGRIRAFLAGLPA
>NZ_AP014582.1|WP_033449714.1|3448248_3449442_+|8-amino-7-oxononanoate-synthase
MSKLDSLFTAALEQAAQRQVRRRLRRATAAPPGRLALDGRTLVNFSSNDYLGLARHPLLAERASLWATRHGAGAQASRLVCGNLDLHEQVEAKLARLKGTEAALLLASGWQANAAVLPALFKAAAAQGEPQVYTDRLNHASLHHGCQAAGVRQIRFRHNDLAHLEHLLAERAGAPGARFIVTESVFSMDGDRADVPALAALAARHHAFLYLDEAHATGVLGPRGMGLAGLAPGGVDLAMGTFSKGLGSFGAYVAGSRALCDYLVNACSGFIYTTALPPAVLGAIDAALDLVPRLDQARAALLGHGERLRASLAAQGIDCGASSTQIVPAIVGDAGHALALAAELERRGLLAVAIRPPTVPAGTSRLRIALSAAHGEAELDQLIEALAAGWRAVRQAA
>NZ_AP014582.1|WP_003810375.1|3446870_3448145_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MSDTTPAWMAQGYPHIWLPYAQMKTAAPPLPVVRSHGSLLELADGRTLIDGVASWWTACHGYNHPHIAQAVREQLDRMPHVMFGGLAHEPALNLASRLSALLGPGLERVFYTDSGSVAVEVAMKMAVQFWLNQGERGRTRFVAFRGGYHGDTFGTMAVCDPDEGMHAMFRGLLPEHDVLALPRDEAALAALQAHLERHAGRIAGMLVEPLVQGAGGMLLHDPQVLARLRELADRYGILLIFDEIFTGFGRTGTMFAFEQAGVRPDIVTLSKALTGGTLPLAATVASARVFEGFWSDDPGHALMHGPTFMGCALACAAANASLDLFEREPRLRQVAALEQALRAGLEPCRDLPWVRDVRVLGAIGVIELDGIGARDDLRRRLVDAGVWVRPFGNIVYLTPAFTIAEDELQALLAAVRQVVAERRP
>NZ_AP014582.1|WP_010926789.1|3445831_3446806_-|membrane-protein
MRPTSILAVPADLPGADRQARRHALVRLGVAWLAMMQVMMFAWPGYVRNDGIPADALATLDWAIVLMNWAALLMTVPVVLYCAWPIWRGAASGLRRGRAGMDAPVALGIVAAFVPSVHATWTGRGEVYFDSVTMFVAFLLTARYLELCARQACGACALATPLVRRLHQAGGELGAAADRLATRFVFVQVALALAAGAAWTQIDAAHAVPVMVALLVMSCPCAMSMAVPSAMACAHSALLARPEATAAQGDALLAAAARVARQNLYGSLAWHLLMTPLALAGWVAPWLAAITMLLSSLAVAGNAWRLRRHRWDAAPAAAVAQPAP
>NZ_AP014582.1|WP_003810379.1|3445691_3445835_-|cbb3-type-cytochrome-oxidase-assembly-protein-CcoS
MSILYLLLPLSLAFVLAIGVALWWAVFSGQYDDTEDQGAAILRDNDN
>NZ_AP014582.1|WP_003810381.1|3444079_3445567_-|cytochrome-c-oxidase,-cbb3-type-subunit-I
MNDCSAIASKAETFNYKVVRQFAIMTVVWGIVGMAVGVLIAAQLIWPQLNFDTAWLSYGRLRPLHTNAVIFAFGGSALFATSYYVVQRTCQARLFCDKLAAFTFWGWQAVIVAAAITLPMGFTSSKEYAELEWPIDILITLVWVAYAVVFFGTIVKRRSRHIYVANWFFGSYILTIAILHIFNNIEMPVTLWKSYSAYAGVQDAMVQWWYGHNAVGFFLTTSFLGMMYYFVPKQAGRPIYSYRLSIVHFWALAFTYMWAGPHHLLYTSLPDWTQSLGMTFSLILLAPSWGGMINGIMTLQGAWHKLRTDPILKFLVTALSFYGMSTFEGSMMSIRTVNSLSHYTDWTIGHVHSGALGWVAMITFGSLYYLIPRLYGRQQMHSVRAMELHFWVATIGVVLYIAAMWIAGVQQGLMWRDTAADGTLVYSFVEELKTRVPYYVIRLAGGILYLSGVFVMAWNVWMTVRGARAVNPAIPLENDNRATAPAGVPAAVPAV
>NZ_AP014582.1|WP_003818550.1|3453696_3455019_-|isocitrate-lyase
MSNRETEIRNLQKDWAENTRWQGIKRAYSAEDVIRLRGSVAVEHSLARRGATRLWDSLHSEPFVNSLGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPQVVRRINNALARCDQIQWMEGKNPGDQDYIDYYAPIVADAEAGFGGVLNAFELMKAMIEAGAAGVHFEDQLASVKKCGHMGGKVLVPTREAVSKLVSARLAADVMGTPTILLARTDADAADLVTSDVDENDRPFITGERTVEGFFRTRAGLDQAISRGLAYAPYADLIWCETSTPNLEYARKFAEAVHRQFPGKLLAYNCSPSFNWKKNLDDGTIAKFQRELGAMGYKFQFITLAGFHALNYGMFELAHGYARRQMSAFVELQQKEFAAAELGFTAVKHQREVGTGYFDAVTQTIEGGQSSTTALTGSTEEAQFEQGGQAVKAA
>NZ_AP014582.1|WP_033447527.1|3455337_3456159_+|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MSLSNAPLGQHVAYPSQYDPGLLFPIPRATNRASLQLGATLPFTGVDLWNAYELSWLDARGKPRVAMATFSFPADSPNIVESKSFKLYLNSFNQTRLPNAQALRDRLERDLAAAAGAPVELEFISPQRFGELNMAELDGIYIDKLDIEIDTYEPAPQLLQCAPGDEVEETLATRLLKSNCPVTGQPDWASLQVRYRGRPIDRAALLKYVVSFRQHAEFHEHCVERIFGDIMRACQPRQLTVYARYTRRGGLDINPWRSNFESAPPADVRTARQ
>NZ_AP014582.1|WP_003810358.1|3456165_3457419_-|MFS-transporter
MAMNSETAVLDSPALRRRDWQIILLIGVAHSSSHFFQLVLPSLYVSLGTEFGLDFARLGLLVSVFYVVSGLGQASSGFVVDRIGARPVLWFGLACFVLSAVLIGAASGYAMLMLAAAIGGIGNSVFHPADYSIINHRVSPPRLGHAFSLHGLTGNLGWALTPVFITTITLLASWRVAAFSAAALVAVVLLMTVIGRDLLGGAAPAEAGGKSAARPAAQESVWQTLAALLARPALWGAFLFFACTSIALSSVQNYTIPLLGQLYDLSKVAASSALSGYMVASALGMAAGGFLVSANPRTELTVTAALIMAGLTLVVLAMGWVPAGWAALVVGLAGFCSGVAAPSRDMLIRRVTPKGATGSVYGLVYSGMDVGSALGPLGFGLLLDAGMAHGPWVGAGVAFAAAALLAQWIAMQARRTA
>NZ_AP014582.1|WP_003810356.1|3457582_3458155_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MPINVPIFLTWLRIAMIPLVVGLFYLPESWMSVPMRDTFAAWAFIIAALTDWFDGWLARRWNQTSAFGAFLDPVADKLMVCAALIVLLDLSRVDAFISLIIIGREITISALREWMAKIGASASVAVHRLGKFKTAAQMVAIPCLLYDQPLFGLSSRLIGDVLIVVAAVLTVWSMLYYLQRAWPAIREKSQ
>NZ_AP014582.1|WP_033447532.1|3458194_3460024_-|excinuclease-ABC-subunit-UvrC
MPDDFNLKSFLADLPHLPGVYRHLDAAGEVMYVGKARDLKKRVSSYFQKNLASPRIAQMVAKVASVDVTVTRSEAEALLLENNLIKSLRPRYNILFRDDKSYPYLLITGHAWPRIAYYRGATSKRGQYFGPYPNSWAVRETIQILQKVFRLRTCEDTVFANRSRPCLLHQIGRCSAPCVGVIEAGDYAHDVQRAVRFLNGEAREVMDEIEARMLQASTELRFEEAAVLRDQMGSLSKVLHQQTMENVGGDDTDVIAVASAGGKICVNLAMVRGGRHLGDKPFFPTHAEGEQPDQVLEAFVAQHYADGAMPPVLVCSHALPDSGLVGLLAEQGGTRVARVLTRPQGVRRSWLEQAQKNAEMALARALTESGARAGRTLALAEALDLDTDEESLDALRIECFDISHTAGEATQASCVVFLHHDMQPSLYRRYNIVGITPGDDYAAMRQVLTRRFGKVADGEAPMPGLVLIDGGKGQVEVARQVFVELGLDIQSLVGVAKGEGRKVGLETLVFADGRPPVALGKESAALMLIAQVRDEAHRFAITGMRARRAKTRNVSRLEEIEGIGARRRQRLLARFGGLSGVSSASIEDLASVEGISQELAVRIYDALHG
>NZ_AP014582.1|WP_003810348.1|3459986_3461048_-|beta-N-acetylhexosaminidase
MSSKKKTKPVLPPGPVMVDVAGTTLTKDEKRRLRNPLVGGVILFARNFTDRRQLCALTRAIHKARKEPLLIAVDHEGGRVQRFRDDGFTALPPMQELGKLWDRDPLAAMRLATEAGYVLAAELRACGVDLSFTPVLDLDYGVSKVIGNRAFHHDARVVTMLSRALAQGLALAGMAACGKHFPGHGFVGADSHHEIPVDPRPLARILKDDAAPYAWLGDLVMPAVMPAHVIYPKVDAQPAGFSRRWVSEILRERLGYDGVVFSDDLTMEGASVAGDILARAEAALGAGCDMVLVCNRPDLADELLDRLQVQHPAASVERIRRLMPRFAAPDWDTLQNDSRYQHARRLQSQIVSG
>NZ_AP014582.1|WP_003810346.1|3461085_3461547_-|holo-ACP-synthase
MSSVSAAGATPPASPGCIAGIGMDLLRIERIERALARHGDRFAQKILGPEELAKFHARRRRDPARGVRFLATRFAAKEAFSKAIGLGMRMPMSWRRVQTLNAPGGRPVLVIGAELADWFDARFGAAHVSITDESDMAAAYVIVERKPAPDGRP
>NZ_AP014582.1|WP_003810344.1|3461631_3462378_-|pyridoxine-5'-phosphate-synthase
MIELGVNIDHVATLRQQRHTAYPDPVQAALRAEDAGADLITLHLREDRRHIQDADVYAIRPLLRTRMNLECAVTPEMLEIACAVKPSDVCLVPEKRTELTTEGGLDVAGAQAAVTDAVQLLAEAGIRVSLFIDPDARQIEAAARAGAPVIELHTGAYAEARDDAAVQAELARVRAAVAEGLRHGLRVNAGHGLHYGNVQAVAALDGIAELNIGHAIVAQSIFDGWDKAVRDMKALMVQARLAAVRGHA
>NZ_AP014582.1|WP_042144744.1|3462374_3463874_-|efflux-transporter-outer-membrane-subunit
MMAVMYKRSALSVLVAAALAGCSLAPDYKRPEAPVQANWPDQPKVQYGAYASPTSLGEQPAAAVAPQGATPADEIGWREFFRDARLQKLIELALVNNRDLRVAVQRVEEARAQYGVQRGAQWPSIGAGIQGQRQHLPPDMRPLGPDSTSISSQYQAGLGLTTFEIDLFGRLRNLSEAAYQQYLSTEQAQRSVHITLVGAVAQSYFNLRAAEVQLELTQKTLASRQESYNLVKTRFDGGVASELDLNQSKSLLDSASADLAALARARAQAANALVVLVGLPGLPEDLPAPAVFGRDQLLASVPAGLPSDLLTRRPDILAAENQLKAANANIGAARAAFFPTISLTGLLGVASPSLDNLFKGGQGYWSFSPSITTPLFAGGSIREGLNLAKARDNIAVAQYEQSIQQAFREVSDALAGEVTYSAQLDAQRALQVAAGRTLELSNLRYNNGIDSYLQVQTAQVDFFNAQLGLVQTGLAALINRVELYKALGGGWQESTTKQP
>NZ_AP014582.1|WP_003810340.1|3463870_3467101_-|multidrug-efflux-RND-transporter-permease-subunit
MPQFFIDRPIFAWVVALFILLTGILAIPNMPVSQYPDVAPPAITITATYPGASAKEVAESVTSIIEDQLNGAKGLLYYESVSDSYGQSQITATFAPGTDPDLAQVDVQNRVSNVTAQLPVAVMQQGLQYEQTSAGFLMIVTLSSTDGTLDQTALADYITRNVKNPVSRVPGVGQFQLFAAPRAMRIWVDPDKLVGFNLSMAEVNQAISQQNVLISAGSIGAPPNPDSQRATATVIVNGQLSTIEGFGQIVLRANTDGSKVLLRDVARIEVGADNYQFGARLNGKPTAAFAIVLSPDANALATAEGVRQQMASLSQYFPSNIRYDIPYDTAPYVKVSIEQVIHTLVEAMVLVFLVMFLFLQNVRYTLIPALVVPVAMLGAFAVMLALGFSINVLTMFAMVLAIGILVDDAIVVVENVERIMASEGLSPKEATKKAMPQISGAIVGITLVLVTVFLPLAFMTGSVGVIYRQFSVAMAVSIFFSAFLALSFTPALCATILKPIPKGHHQEKKGFFGWFNRKFDATTHNYQNWVSRILHKGGRMMLAFALLVVLLGWLYMRLPSSFLPEEDQGYVVSNIELPTGASANRTIEVIEEVENYFRNIPAVENVITVQGYSFNGNGLNAAIAFTTLKDFSERKSRADSAGAIAFTAFSKQLMGIHDAQVFTLVPPAISSLGNASGFDFRLQDRGGAGTEALGAATAELMGMAAKSPVLSQVRITGLGPGSQLSLTIDRDKAAALGVNFDEAATLISTAVGSAFLNKFPNMGRMQNIWVQADQQYRMQVEDLLKLNARNNQGGMVPLSTFVSAKWVQGPVQVVRYNSYESVRIGGDAAAGYTTGEAMQEMQDLVARLPQGFGYEWNGLSYQERLAGNQAPILMGLALLVVFLVLAALYESWAIPLSVMLVVPLGMLGAVALVTVLGMSNDVYFQVGMVTVIGLAAKNAILIVEFAKDQYARGQGLYESAVEAARLRFRPILMTSLAFILGVVPLAIATGAGAASQRAVGIGVLGGMLAATPFAVIFVPTFFVVVLGLFKTRPRLLGAELRAFEEEQAAKRAAEQQQPQDGAATPAPQTGGQENKE

Crispr_ID: NZ_AP014582_8

• CRISPR_ID: NZ_AP014582_8
• CRISPR_location: 4389304-4389397
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP014582_8

Consensus_repeat	Method
GTGCCTGTCCCCGCCGGGACAGGCAC	CRISPRCasFinder

spacers of NZ_AP014582_8

>8.1|4389330|42|NZ_AP014582|CRISPRCasFinder
CCGGGCCCAGGAAAACCCCCACGCTGCGCCCGCTGTGCGGGC

CRISPR arrays and Neighbor proteins around NZ_AP014582_8

CRISPR arrays

The CRISPR arrays of NZ_AP014582_8

>merge|NZ_AP014582|8|4389304-4389397|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGCACCCGGGCCCAGGAAAACCCCCACGCTGCGCCCGCTGTGCGGGCGTGCCTGTCCCCGCCGGGACAGGCAC

>NZ_AP014582|8|8|4389304-4389397|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGCAC	CCGGGCCCAGGAAAACCCCCACGCTGCGCCCGCTGTGCGGGC
GTGCCTGTCCCCGCCGGGACAGGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014582.1|WP_003814691.1|4384140_4385373_-|CoA-transferase	unknown	unknown	gnl|CDD|367110
NZ_AP014582.1|WP_003814678.1|4380038_4381211_-|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|173841
NZ_AP014582.1|WP_003814704.1|4390486_4391887_-|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NZ_AP014582.1|WP_157734664.1|4396175_4396448_+|GtrA-family-protein	unknown	unknown	gnl|CDD|377229
NZ_AP014582.1|WP_003814681.1|4381336_4382314_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176106
NZ_AP014582.1|WP_003814706.1|4392075_4392990_+|DMT-family-transporter	unknown	unknown	gnl|CDD|223769
NZ_AP014582.1|WP_003814711.1|4394664_4395120_-|multidrug/biocide-efflux-PACE-transporter	unknown	unknown	gnl|CDD|226610
NZ_AP014582.1|WP_003814685.1|4382324_4383296_-|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270234
NZ_AP014582.1|WP_003814689.1|4383362_4384148_-|crotonase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|181723
NZ_AP014582.1|WP_033452651.1|4396407_4398027_-|glycosyltransferase-family-39-protein	unknown	unknown	gnl|CDD|224720
NZ_AP014582.1|WP_003814694.1|4385568_4386324_-|TerC-family-protein	unknown	unknown	gnl|CDD|223930
NZ_AP014582.1|WP_003814713.1|4395116_4396220_-|ChbG/HpnK-family-deacetylase	unknown	unknown	gnl|CDD|212118
NZ_AP014582.1|WP_033452649.1|4393735_4394659_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|378820
NZ_AP014582.1|WP_003820700.1|4390042_4390387_-|TIGR01244-family-phosphatase	unknown	unknown	gnl|CDD|225984
NZ_AP014582.1|WP_003814701.1|4389483_4389954_-|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NZ_AP014582.1|WP_010927085.1|4392986_4393646_+|LysE-family-translocator	unknown	unknown	gnl|CDD|224199
NZ_AP014582.1|WP_003814697.1|4386434_4386953_+|MgtC/SapB-family-protein	unknown	unknown	gnl|CDD|224204
NZ_AP014582.1|WP_033452647.1|4386949_4389073_-|elongation-factor-G	unknown	unknown	gnl|CDD|234569
NZ_AP014582.1|WP_010929793.1|4378983_4380012_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|366103
NZ_AP014582.1|WP_003814674.1|4377724_4378918_-|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl|CDD|180775

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP014582.1|WP_003814691.1|4384140_4385373_-|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	8.36236e-118
NZ_AP014582.1|WP_003814678.1|4380038_4381211_-|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	6.87275e-84
NZ_AP014582.1|WP_003814704.1|4390486_4391887_-|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.52472e-110
NZ_AP014582.1|WP_157734664.1|4396175_4396448_+|GtrA-family-protein	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	1.3327e-06
NZ_AP014582.1|WP_003814681.1|4381336_4382314_+|LysR-family-transcriptional-regulator	gnl|CDD|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.33368e-60
NZ_AP014582.1|WP_003814706.1|4392075_4392990_+|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	8.05606e-10
NZ_AP014582.1|WP_003814711.1|4394664_4395120_-|multidrug/biocide-efflux-PACE-transporter	gnl|CDD|226610	COG4125, COG4125, Predicted membrane protein [Function unknown].	2.35069e-54
NZ_AP014582.1|WP_003814685.1|4382324_4383296_-|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl|CDD|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	2.06741e-117
NZ_AP014582.1|WP_003814689.1|4383362_4384148_-|crotonase/enoyl-CoA-hydratase-family-protein	gnl|CDD|181723	PRK09245, PRK09245, crotonase/enoyl-CoA hydratase family protein.	2.06175e-156
NZ_AP014582.1|WP_033452651.1|4396407_4398027_-|glycosyltransferase-family-39-protein	gnl|CDD|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	2.23603e-50
NZ_AP014582.1|WP_003814694.1|4385568_4386324_-|TerC-family-protein	gnl|CDD|223930	COG0861, TerC, Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism].	1.14565e-78
NZ_AP014582.1|WP_003814713.1|4395116_4396220_-|ChbG/HpnK-family-deacetylase	gnl|CDD|212118	cd10807, YdjC_like_3, uncharacterized YdjC-like family proteins from bacteria. This subfamily contains many hypothetical proteins, and belongs to the YdjC-like family of uncharacterized proteins from bacteria. The YdjC-family is represented by an uncharacterised protein YdjC (also known as ChbG) encoded by the chb (N,N'-diacetylchitobiose, also called [GlcNAc]2) or cel operon in Escherichia coli, which encodes enzymes involved in growth on an N,N'-diacetylchitobiose carbon source. The molecular function of this subfamily is unclear.	1.3947e-92
NZ_AP014582.1|WP_033452649.1|4393735_4394659_+|alpha/beta-fold-hydrolase	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	1.80059e-21
NZ_AP014582.1|WP_003820700.1|4390042_4390387_-|TIGR01244-family-phosphatase	gnl|CDD|225984	COG3453, COG3453, Uncharacterized protein conserved in bacteria [Function unknown].	3.40043e-35
NZ_AP014582.1|WP_003814701.1|4389483_4389954_-|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.38587e-30
NZ_AP014582.1|WP_010927085.1|4392986_4393646_+|LysE-family-translocator	gnl|CDD|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	4.25651e-32
NZ_AP014582.1|WP_003814697.1|4386434_4386953_+|MgtC/SapB-family-protein	gnl|CDD|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	1.52093e-44
NZ_AP014582.1|WP_033452647.1|4386949_4389073_-|elongation-factor-G	gnl|CDD|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	0
NZ_AP014582.1|WP_010929793.1|4378983_4380012_-|acyl-CoA-dehydrogenase	gnl|CDD|366103	pfam00441, Acyl-CoA_dh_1, Acyl-CoA dehydrogenase, C-terminal domain. C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle.	3.23873e-12
NZ_AP014582.1|WP_003814674.1|4377724_4378918_-|acetyl-CoA-C-acyltransferase	gnl|CDD|180775	PRK06954, PRK06954, acetyl-CoA C-acetyltransferase.	6.15168e-175

Protein sequences

>NZ_AP014582.1|WP_033452647.1|4386949_4389073_-|elongation-factor-G
MTRRTSIERYRNIGISAHIDAGKTTTTERILFYTGITHKLGEVHEGAATMDWMEQEQERGITITSAATTAFWRGMAGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYDSVGGVQPQSETVWRQANKYGVPRIAFVNKMDRVGADFFRVQRQIVERLKGDAVPIQIPVGAEDHFEGVVDLVKMKAIIWDDASQGVRFEYRDIPPELQAQAEQWREKMIEKAAEANEALLEKYLSGQPLSEDEIKSGLRARTVANEIVPMLCGSAFKNKGVQAMLDAVIDYLPSPADVPAIIGHDERDREIERHPADDEPFSALAFKIMTDPFVGQLIFFRVYSGVVKSGDSVLNPLKSKKERLGRILQMHANERREISEVYAGDIAAAVGIKEITTGDTLTDPAHVIILERMTFPEPVISQAVEPRTKADQEKMGIALNRLAQEDPSFRVRTDEESGQTIISGMGELHLEILVDRMKREFGVEANVGKPQVAYRETIRSTVTDVEGKFVKQSGGRGQYGHVVLKLEPQEQGKGYEFVDAIKGGVVPREFIPAVDRGVRETLNTGVLAGYPVVDVKVTLVFGSYHDVDSNENAFRMAASMAFKEGMRRAKPVLLEPMMHVEVETPEDFTGNVMGDLSSRRGMVQGMEDIAGGGGKLVRAEVPLAEMFGYSTSLRSLTQGRATYSMEFKHYAEAPRQVAEQIIAARGSGAAARG
>NZ_AP014582.1|WP_003814697.1|4386434_4386953_+|MgtC/SapB-family-protein
MDTVWMEIWTTVRNEFADIPDVAEATRIVLRLGMAVALGGLLGYERERSGKAAGLRTHMLVALGAALFVLVPLQGGMEVGDLSRVLQGVIAGIGFLGAGAIIKLGNEGEIRGLTTSAGIWLTAAIGVAAGMGREATALASTLIALFVLAALRRLEKRIAARDDKRVVAQPPP
>NZ_AP014582.1|WP_003814694.1|4385568_4386324_-|TerC-family-protein
MDYLVSLAQQPAAWAALATLIAMEVVLGIDNLIFISILTNKLPPQHQTKARRIGIGMALILRLALLGTVAFIVQLTQPVFELFGHGFSWRDVILVAGGLFLVWKATKEIHHHVDPNPGDDMFGGKAATLGFAAAVAQILMLDLVFSIDSIITAVGMTEHIPIMFVAVIVAVAVMLLAAEPLARFIERNPTVVMLALAFLMMIGMTLIAEGFGAHVPKGYIYAAMAFSALVEGLNMMARRAREGRGAGAAGG
>NZ_AP014582.1|WP_003814691.1|4384140_4385373_-|CoA-transferase
MSGPLEGVRILDVTTVLMGPYATQILGDLGADVIKVEPPAGDNVRGIGPGRHADMGGIFLHANRSKRSIALDLKNPAGREALLKVAATCDVLVYNVRPQAMARLGLSYAEVAQANPSILYVGMYGYDQRGPYAARAAYDDLIQGAVGIPSLSVEAGSDIPRYAPSAMVDRIVGISAANAVTAGLYHRARTGQGQAIDVPMFETMAHLILGDHMMGQTFEPPLGPPGYPRILNADRRPYATRNGHICVLLYADKHWKAFFELIGQPGRDAADPRFRDIGTRTQHIHAIYRLVSDAIASRTTEEWLAAFEAADIPAMPVHTMASLLRDPHLEAIGFFGMVDHPSEGAVRMMAVPSRWSGTPPQPRGHAPRLGEHSVDVLKEAGYDDEAIAALVRNGAAIAAARQLPEGTDHD
>NZ_AP014582.1|WP_003814689.1|4383362_4384148_-|crotonase/enoyl-CoA-hydratase-family-protein
MTDFLRHERHGGVLLLTMDRERTRNALSDADAVEALVQACARIGADLSVRAVVLTGSHGVFSSGGNLKTLSDTVGAGLGEPVHSRQAYRSGIQRIPLALYNLEVPTIAAVNGPAIGAGCDLACMCDIRLAARQASFAESFVKLGLTPGDGGAWLLPRIVGMSRACELAFTGRSIDAARARELGLVSEVFDADALLPAALALAQEIAQHSGHALRLTKRLLREGQHTRLDTLLELSAGFQALAHHTQEHAGALDAHLSRKRG
>NZ_AP014582.1|WP_003814685.1|4382324_4383296_-|tripartite-tricarboxylate-transporter-substrate-binding-protein
MHSRTLALALLSVAALAQGGSARAASDYPAHPVKIIVSLPPGSGADTTARFLSKHLAERFKQPFVVENRPGGNSFIAAQAVATAPPDGYTLFVASNSPMTTNAAVFKNLPYDAVKDFAPVAPIARFPMALVVPANSPYRSVADLVAAARAAPGQLNFASGTATYQVVLELFHEQNGIKATHVPYKGTSAALADVAGGVVQYSVADVSAALPLIRGGKLRPLAVTSTRRIKDLPDVPTMQESGNKGFEAYAWTAAFFPAKVDPAIVARVSDAVQALVRSQEGKAFMEQLGGEPFVGGPDTLAAFQRDELASMRRIAKLANIQQE
>NZ_AP014582.1|WP_003814681.1|4381336_4382314_+|LysR-family-transcriptional-regulator
MWTGQYIVHIASPAHHWRRAVELRQLKQLLVLSETLNFHRAAERLHMAQPPLSTAIKKLEQELGVQLFERLPAGLQPTPAAEVVLRYARATLFYADEIQRAAQEGASGKQGMLKVGFVGSSIYSLMPQLLSAFRKDYPRVDLVIEESTTVDLLRRLDAHTLDVALVRFPVLEPSTARITLLQADHLMLAVPAGSRYAQRDDVALDELADEPFIGYSRTHVPGMHALIMYAFQQYGVVPHIAQEAIQVQTILSLVESGLGLAIVPKVACRQAGSGVRLVNVPQLAETIKVGIALAVHPDNATPTTANFVDMACRLMQTEPAAGQAR
>NZ_AP014582.1|WP_003814678.1|4380038_4381211_-|acyl-CoA-dehydrogenase-family-protein
MGAILGTIIEALQLAAIPAHDEALRPAVRAFLDEALREMPADRRARSWMGHDAEFSRALARQGWLGLTLPVEYGGAGRSNFARFVLSEELLAAGAPVSAHWIADRQTAPLILRFGSPAQRAFYLPRIIRGEAFFAIGMSEPDTGSDLASVRTRATPVADGWLLNGRKIWTTNAHRSHYMCALVRTSGAPEDRHRGLSQMIFDLALPGIEIRPIRDIAGDAHFCEVLFDNVLLPHDALVGEEGSGWRQVMAELALERSGPERIYSSMVLLDGWLAHLRRDAAPQRAQVCLAGRLAARLAVLRSMSLAVSQRLEQGADASLAAVLVKDLGTEFEQAVPELIGQALHASPQPAPDDVLMRTLAYLTLINPTFSLRGGTRHILRGIIARELGLR
>NZ_AP014582.1|WP_010929793.1|4378983_4380012_-|acyl-CoA-dehydrogenase
MVSTMQQDLYETFARALAGLCPLERVRELEAAADPRAGAARAWNEVDALGYGDALSPAEHGGAGLSLADAEGLLRAAGAMALPFPFADTLLARALLRAAGQAVPDGPIALGVALPHGAGWRCAPIAGVALAQAVAVEHDGCLALWPAPDAVQPGLFRPRASGAPAWRGTPAQAGRAGAPAGAVQAWRNAADAAGMAGAMQAVLDRCVAYVQERQQFGRALGRFQAVQQDISMLAEQVAAVAMAARLACASGVLFPDPALAACARLRACEAVPVVCALAHAVHGAIGITEELPLGLYTARLHEWRATGMSEDDCAELLGRRVLADGERTLLDVVRGMVSAAHA
>NZ_AP014582.1|WP_003814674.1|4377724_4378918_-|acetyl-CoA-C-acyltransferase
MSVHPDPVVIVAARRTPIGAFQGALAHYSAPQLGAHALAAAVRQAGLQPDAAQEALMGCCLFAGLGQAPARQAVLGAGLPTDVQATTLSKMCGSGMKAAMLAHDMLRAGSADVVLAGGMESMSNAPHLIPKARQGYRLGDGQLLDHMYRDGLQDAYEGRLMGHYADLAAREYGFSREQQDAYAHESVLRAQRSVAEGEFAEEIAPIAGLARRGAPAAMVAVDETPGLCDVSRLASLKPVFNADGTVTAGNASSISDGAAALVLTRQAHAERLGLAPQARIVGHATAALPPGQFPAAPVRAIARLFERVGWDRDSVDLFEINEAFAVVTMIALRELGLPAERVNVNGGACALGHPVGATGARLIVTLMHALRRRGLRRGVACLCLGGGEATAIAVERA
>NZ_AP014582.1|WP_003814701.1|4389483_4389954_-|universal-stress-protein
MFKKILIPTDGSPLSAQAANAGICFARSTGAEVVALHVTQPFAATIGFDGMAAAYAITDEDYEKASAEQAEKYLKLILDRAETAGVKAESRAVSNFNVADGIVQAAGEAGCDLIFIGSHGRSGLSRLLLGSVTAKVLSLAHTAVLVYRVKEDKDKK
>NZ_AP014582.1|WP_003820700.1|4390042_4390387_-|TIGR01244-family-phosphatase
MSAAIKPLTENFAVAPQLGPADMADVAAAGYKSVIINRPDFEGGPDQPTAADVSQAAQALGLQVEYQPVVGSAMTAADVARFAELLRTMPGPVLAYCRTGTRCTNLFAAAQQLG
>NZ_AP014582.1|WP_003814704.1|4390486_4391887_-|PLP-dependent-aminotransferase-family-protein
MRQADATLVTQLADDLARRIDEHGLRPGTRLPSIRRMAEQSGVSRFTVVEAYDRLVARGLVQSRRGAGFFVRARSASLTALASARVPQAAPETPVRVDVSWLLRNMFRETAAGMPGGAGLLPPEWLDPDMVAAAVRAVGRTVRGNLVSYGSPQGYAPLRQQLASMLQADGVPAHPERNLLTTNGVTHGLDIVARHLIKPGDTVLVEDPAWFVIFGRLAAFGARPVGVPRGPDGPDLAMLDRLAAEHKPRLYIINGAVHNPTGHTLSAGAAYDILRLAERHDFMVVEDDTYADLHPGGAMKLAALDRLERVILVGGFSKMLAASLRVGYIAAGAETLQRLTDLKMLAGLTSPELGERVVHRVLVEGQYRRHIERVRARVNEARLRSIQALQQLGLSVPHEPHAGMFVWADCGRDSEPVARNAAERGMLLAPGTLFSPSGAPSTMLRFSVAMVDTPGIWQSIAAVMAQ
>NZ_AP014582.1|WP_003814706.1|4392075_4392990_+|DMT-family-transporter
MSPPSAQASAPSASPHAPSWEGYGYGLIGVLVFALTLPMTRLAVGELSPLLVGLGRALLAAVPAAALLWLTRSRRPDRAEWSGIVLAAVGIVVGWPVASTLAMASVPAAHGAVFNGLLPLSTAVFAAWRSGERPSPAFWSFAVLGAVLVAGYALRQGHGALQPGDLWLLLAVVLGGMGYAEGARASRTLGGWRTICWALVVSVPALLPAVLWLAHDAAWPSLPVAGAFAYLAFGSMFLGFFAWYRGLAIGGIARVGQIQLLQPFLTVVAAALLFNEQVEPITYVFAVAVVLVIAGGRRAMVRKA
>NZ_AP014582.1|WP_010927085.1|4392986_4393646_+|LysE-family-translocator
MIGSDLSSLDQAPLASLSVLMPLVLFTLVNSLTPGPNNVMLASSGLTFGFRRTIPHLLGISVGFSIMLLMVGLGLGATLERLPWLYSTLKYGGAAYLLYLAWKIATSGPMESGAERGKPLTFIQAALFQWVNPKAWVMIVSVVATYTPQHGYFANLIIATLVCGVVNLPSVGVWAAFGMALRRWLHRPAAVRAFNVGMAVLLVVSLYPVGLDLLALYTG
>NZ_AP014582.1|WP_033452649.1|4393735_4394659_+|alpha/beta-fold-hydrolase
MVSLPFRLSWRRMAAVLLLAAGALGFNQLDAWQRQAIFSPQTDQQRWWREPPAGTEVFDLALPNGDKVHAWYWQSPRRDAPTVLYLHGARWNLNGSAFRMEGWTRMGYSMLAIDYRGFGQSTPLLPSEQSASQDAAAALQELARRQPDPARRFIYGHSLGGAIAIDLAARPDLPPFAGLIVESSFTSIGAMLGTMKWGWVPGATLPVTQPFASVDKLAALTTPMLLLHGTADRVVPHTMSDELYRAAQQVPADLKRLVKIEGASHSGAIRSGRIYEDAVADFVRDAGRGYAGRQGAPTPLTASRPGT
>NZ_AP014582.1|WP_003814711.1|4394664_4395120_-|multidrug/biocide-efflux-PACE-transporter
MSSSSKQTPKTIKERFLHAFFFEIIAIGLSAPVAAWAMDQPLFDMGVLTAVIAWIALLWNMVYNAGFERLERRFGVVRTMPVRVAHAVGFELGLVLIIVPLAAWWLAISFWEAFMLDIGLLMFYLPYAFFYNLAYDKLRARWWGRIEPAGA
>NZ_AP014582.1|WP_003814713.1|4395116_4396220_-|ChbG/HpnK-family-deacetylase
MTSERYDEGQQPAHHVGPQRGQAGPFHAGDRDGPMGGGRGASDGNEPGNLSQQAAHVEEVSPLRNQAGDVRCRRIAVCGDDFGMNEAIDGALIELAGAGRLSAVSCMPLAPAFAADAPALARLDVDLGVHVDFTEAFAGAAPAAPGLAALLWRAYAGQLDPDWIDARLASQFDAFERAFGRAPDYVDGHQHVHQLPGILPRLRALLKRRYAGQRIWLRHTAPGLQFGLPLAEAAKARLIGALGAGALARAAGQEGWQTNRRMLGVYGFTGGPRRYAGLLHHWLMNARDGDLLMCHPGWPQVHGAAHASQRAAEYEVLAHPELGTWLARNGLRIVRLSQVRGRQASQESGKVRNVPHSGSFRRLASRL
>NZ_AP014582.1|WP_157734664.1|4396175_4396448_+|GtrA-family-protein
MVGWLLAFVVSFTGHFRLTFRHLAASWTIAARRFFLVSALGFAINELSYAWLLHATSLPYDVLLALVLIGLAFLTFVASRLWAFRHRHAP
>NZ_AP014582.1|WP_033452651.1|4396407_4398027_-|glycosyltransferase-family-39-protein
MTLATRSMQPHAVSPGQARSWPLPAAGWLLLAVGVWLAFLSWMRPLALPDEGRYAGVAWDMLRNGSFAVPLIDGMPYFHKPPLYYWLAELSFRLFGVNEWAARLPSALAAWASAVALYLFVRRHRDAASATLCVLVLATLPLFFGGAQYANMDMLVAGMITLCVLAGADTALRVRGGQAWRAMALATGVCAALAMLAKGLIGLVLPGAILLAWLAWRRDWRGLRALLWPPAILAFAVVAVPWFWLMQVRYPGFFQYFFVHQHFERFAQTGFNNVQPFWFYLPVIAGLALPWSLWAGGLLRKQFWAADADPDGLRRLALVWLAVIVAFFSMPQSKLVGYIMPVLPPLAFLLAEVVMGALRDPAVARATRRMARVSALVAVAICVTAVFVASFNARGSSRELALSLRGELRPNDTLVALHTYPFDLQLYAHAARPMWVVDDWSNPEIPKRDNWRRELYDAVQFEPALGERLLVSADTFQQRLCQAPEGSRYWVWGTAADEEAYAPLRGQAARFADARRSLWLVLVDEAFKGRVCDGTPTGG

Crispr_ID: NZ_AP014582_9

• CRISPR_ID: NZ_AP014582_9
• CRISPR_location: 4524780-4524860
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP014582_9

Consensus_repeat	Method
GTGCCTGTCCCCGCCGGGACAGGC	CRISPRCasFinder

spacers of NZ_AP014582_9

>9.1|4524804|33|NZ_AP014582|CRISPRCasFinder
GCCTGCAAGATTTCATGGCATCTGCCCGTGCGT

CRISPR arrays and Neighbor proteins around NZ_AP014582_9

CRISPR arrays

The CRISPR arrays of NZ_AP014582_9

>merge|NZ_AP014582|9|4524780-4524860|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGCGCCTGCAAGATTTCATGGCATCTGCCCGTGCGTGTGCCTGTCCCCGCCGGGACAGGC

>NZ_AP014582|9|9|4524780-4524860|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGC	GCCTGCAAGATTTCATGGCATCTGCCCGTGCGT
GTGCCTGTCCCCGCCGGGACAGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014582.1|WP_003814951.1|4528689_4530036_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	unknown	unknown	gnl|CDD|236307
NZ_AP014582.1|WP_003814956.1|4533109_4533703_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|225692
NZ_AP014582.1|WP_003814946.1|4524964_4525468_-|glycine-zipper-2TM-domain-containing-protein	unknown	unknown	gnl|CDD|225675
NZ_AP014582.1|WP_003814933.1|4519939_4520515_+|YggT-family-protein	unknown	unknown	gnl|CDD|376765
NZ_AP014582.1|WP_003814937.1|4521996_4523124_-|membrane-bound-O-acyltransferase	unknown	unknown	gnl|CDD|274974
NZ_AP014582.1|WP_033452676.1|4517603_4518806_+|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl|CDD|235968
NZ_AP014582.1|WP_033452679.1|4526594_4527722_-|DUF3426-domain-containing-protein	unknown	unknown	gnl|CDD|378759
NZ_AP014582.1|WP_033452681.1|4530045_4530495_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	unknown	unknown	gnl|CDD|235777
NZ_AP014582.1|WP_003814954.1|4531097_4531646_-|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NZ_AP014582.1|WP_003814941.1|4523253_4524381_-|D-alanyl-lipoteichoic-acid-biosynthesis-protein-DltD	unknown	unknown	gnl|CDD|368189
NZ_AP014582.1|WP_003814943.1|4524406_4524646_-|acyl-carrier-protein	unknown	unknown	gnl|CDD|223314
NZ_AP014582.1|WP_003814930.1|4519123_4519801_+|histone-H1-like-DNA-binding-protein	unknown	unknown	gnl|CDD|237855
NZ_AP014582.1|WP_003814953.1|4530584_4531019_-|type-II-3-dehydroquinate-dehydratase	unknown	unknown	gnl|CDD|235443
NZ_AP014582.1|WP_003814928.1|4514654_4517582_+|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl|CDD|235966
NZ_AP014582.1|WP_003814925.1|4510261_4510714_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224439
NZ_AP014582.1|WP_003814950.1|4527747_4528671_-|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl|CDD|283886
NZ_AP014582.1|WP_003814926.1|4510842_4514349_+|indolepyruvate-ferredoxin-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|237279
NZ_AP014582.1|WP_010927112.1|4520522_4521986_-|D-alanine--poly(phosphoribitol)-ligase	unknown	unknown	gnl|CDD|341267
NZ_AP014582.1|WP_003814955.1|4531728_4533099_+|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase	unknown	unknown	gnl|CDD|130153
NZ_AP014582.1|WP_003814947.1|4525641_4526583_-|carbohydrate-kinase-family-protein	unknown	unknown	gnl|CDD|238917

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP014582.1|WP_003814951.1|4528689_4530036_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	gnl|CDD|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	0
NZ_AP014582.1|WP_003814956.1|4533109_4533703_+|alpha/beta-fold-hydrolase	gnl|CDD|225692	COG3150, COG3150, Predicted esterase [General function prediction only].	8.39901e-54
NZ_AP014582.1|WP_003814946.1|4524964_4525468_-|glycine-zipper-2TM-domain-containing-protein	gnl|CDD|225675	COG3133, SlyB, Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane].	3.3638e-32
NZ_AP014582.1|WP_003814933.1|4519939_4520515_+|YggT-family-protein	gnl|CDD|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	2.04276e-07
NZ_AP014582.1|WP_003814937.1|4521996_4523124_-|membrane-bound-O-acyltransferase	gnl|CDD|274974	TIGR04091, hypothetical_protein, D-alanyl-lipoteichoic acid biosynthesis protein DltB. Members of this protein family are DltB, part of a four-gene operon for D-alanyl-lipoteichoic acid biosynthesis that is present in the vast majority of low-GC Gram-positive organisms. This protein may be involved in transport of D-alanine across the plasma membrane. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	6.72878e-50
NZ_AP014582.1|WP_033452676.1|4517603_4518806_+|ribonucleotide-diphosphate-reductase-subunit-beta	gnl|CDD|235968	PRK07209, PRK07209, ribonucleotide-diphosphate reductase subunit beta; Validated.	0
NZ_AP014582.1|WP_033452679.1|4526594_4527722_-|DUF3426-domain-containing-protein	gnl|CDD|378759	pfam11906, DUF3426, Protein of unknown function (DUF3426). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 262 to 463 amino acids in length.	1.69179e-42
NZ_AP014582.1|WP_033452681.1|4530045_4530495_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	gnl|CDD|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	2.94729e-77
NZ_AP014582.1|WP_003814954.1|4531097_4531646_-|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	8.20462e-37
NZ_AP014582.1|WP_003814941.1|4523253_4524381_-|D-alanyl-lipoteichoic-acid-biosynthesis-protein-DltD	gnl|CDD|368189	pfam04914, DltD, DltD protein. DltD is and integral membrane protein involved in the biosynthesis of D-alanyl-lipoteichoic acid. This is important in controlling the net ionic charge in lipoteichoic acid (LTA). This family is found in bacteria of the Bacillus/Clostridium group. DltD binds Dcp and ligates it with D-alanine. DltD does not ligate acyl carrier protein (ACP) with D-alanine. It also has thioesterase activity for mischarged D-alanyl-acyl carrier protein (ACP). DltD is thought to be responsible for discriminating between Dcp involved in the D-alanylation of LTA, and ACP involved in fatty acid biosynthesis.	1.09917e-76
NZ_AP014582.1|WP_003814943.1|4524406_4524646_-|acyl-carrier-protein	gnl|CDD|223314	COG0236, AcpP, Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	3.22825e-07
NZ_AP014582.1|WP_003814930.1|4519123_4519801_+|histone-H1-like-DNA-binding-protein	gnl|CDD|237855	PRK14900, valS, valyl-tRNA synthetase; Provisional.	8.36238e-15
NZ_AP014582.1|WP_003814953.1|4530584_4531019_-|type-II-3-dehydroquinate-dehydratase	gnl|CDD|235443	PRK05395, PRK05395, type II 3-dehydroquinate dehydratase.	2.95712e-86
NZ_AP014582.1|WP_003814928.1|4514654_4517582_+|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl|CDD|235966	PRK07207, PRK07207, ribonucleoside-diphosphate reductase subunit alpha.	0
NZ_AP014582.1|WP_003814925.1|4510261_4510714_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	8.87588e-45
NZ_AP014582.1|WP_003814950.1|4527747_4528671_-|50S-ribosomal-protein-L11-methyltransferase	gnl|CDD|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	9.01589e-110
NZ_AP014582.1|WP_003814926.1|4510842_4514349_+|indolepyruvate-ferredoxin-oxidoreductase-family-protein	gnl|CDD|237279	PRK13030, PRK13030, indolepyruvate ferredoxin oxidoreductase family protein.	0
NZ_AP014582.1|WP_010927112.1|4520522_4521986_-|D-alanine--poly(phosphoribitol)-ligase	gnl|CDD|341267	cd05945, DltA, D-alanine:D-alanyl carrier protein ligase (DltA) and similar proteins. This family includes D-alanyl carrier protein ligase DltA and aliphatic beta-amino acid adenylation enzymes IdnL1 and CmiS6. DltA incorporates D-ala in techoic acids in gram-positive bacteria via a two-step process, starting with adenylation of D-alanine that transfers D-alanine to the D-alanyl carrier protein. IdnL1, a short-chain aliphatic beta-amino acid adenylation enzyme, recognizes 3-aminobutanoic acid, and is involved in the synthesis of the macrolactam antibiotic incednine. CmiS6 is a medium-chain beta-amino acid adenylation enzyme that recognizes 3-aminononanoic acid, and is involved in the synthesis of cremimycin, also a macrolactam antibiotic. The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions.	0
NZ_AP014582.1|WP_003814955.1|4531728_4533099_+|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase	gnl|CDD|130153	TIGR01081, mpl, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. Alternate name: murein tripeptide ligase [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_AP014582.1|WP_003814947.1|4525641_4526583_-|carbohydrate-kinase-family-protein	gnl|CDD|238917	cd01942, ribokinase_group_A, Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.	8.05228e-106

Protein sequences

>NZ_AP014582.1|WP_003814943.1|4524406_4524646_-|acyl-carrier-protein
MHTEQELHTRIADIVESIILKKVTPDTALISSGLVDSLAAVDITLAVESEYGCSIPAPEIAEHLQSVRTLAGYVAANSQ
>NZ_AP014582.1|WP_003814941.1|4523253_4524381_-|D-alanyl-lipoteichoic-acid-biosynthesis-protein-DltD
MASAVALSLGLYWGADGALSALVHPHSSVASVRDNYLPNLGPDWGTQNVNLNRLGNALADGTLVVLGSSELSSHDLRFVPYRFFPQELKVPTLAYGHAMFQSYGIVSVLEAVADSLTPNTRLVIMVSPAWFASGGQLPRSAFAEHVTGPVWDRLWDKPATREQMQDWIADNANWGLLWLIANGQVAELKDKIALWWNSRGERAPDRPRSPLAVPAHKYVSWPAAARLDAGRWHDLLGQARGIEAELGGHNPYDVRDDYYRQYLAPLNSPARNEFPEMPPMTRPELGDLARVMALLQQRKVRAYFVIQPFNPKLILDVERFDPVADAIKGMCARYGMGCLDMYSVPFQPGMVRDDMHLAELGWAIADQGIAEFFSR
>NZ_AP014582.1|WP_003814937.1|4521996_4523124_-|membrane-bound-O-acyltransferase
MELFGSFAFFGGALFGGLGLLLYRALGLPWRLGYRHLIGALCLAVWLAVFWTRPYQPLGLLAVASAALWAMRRGHLPTWAAVLLTMAPLLLLKCGITTMTGMLGLSFATFRAVDVLLFAPRNERISPLDYCIYLFFPLTLLAGPMYRWRNFQADLKRGYEGVTLETWLAGLELLIFGVIQKFGVAEAIWRYGLNTLDAHDYSLTGVALNASLYSFYLFFDFAGYSSMAIGVGMLFGFTLPVNFRNPLASANPQDFWRRWHISLSEWLRDVVFMPIYKALSKTAFFGRHRLAAQNIGILATLLAMGVWNGLALHYVVSGLMFGAYSVGHNLLVQHARTRPALQAFLARRPVQWAGRALTLILAALALYVFSGRSPI
>NZ_AP014582.1|WP_010927112.1|4520522_4521986_-|D-alanine--poly(phosphoribitol)-ligase
MRGMYFDLRSFEFVSDARGGQADAVVGSDRVLTWQALREEACQWAARARAHGIGPDVPVVIHGHKEAAFFVAMAGALLAGAPFVPVDTIYPPERVRRIVEIVRAAAVYDTQADVFRPGAAEPAALAERGLAYVMFTSGSTGDPKGVQIGRESVALLGDWLRDGLALGEAPVFMNQAPFSFDLSMYEVFGTLAAGGTCVLNAREQIAAPQQWLARLAGSGVTVWVSTPSFAHQQLANRDFSPQQLRALRTFLFCGEPLPVALARKLRQRFPEAAILNTYGPTEATVATTALVVDDAVLAEHDPLPVGYAKPASLLYVADDEICIVGDHVMRGYLNRPDLNQAKLFVHHDGRRGFRTGDLGRMREDGLLFCRGRMDDQIKLNGYRIELAEIDAALHALPGVAGGACAVLRRPDGTAVRVIGFVAQRTVEQASFQLPAALQQWKAQLTGRLPSYMVPSELVACPDLPVSNNHKIDRKKLLEIYAAIPAAA
>NZ_AP014582.1|WP_003814933.1|4519939_4520515_+|YggT-family-protein
MATALMLGDIIRFLLEITFTLFGAALILRAWIHAVRLHPFNPLARAIYQGTNWLVLPLRRVIPATGSIDWTSLIAAWVAALIYLILVWLSAVGALPPASALPSAMGSALLMVLKWTLNLMVWMTLIQAVLSWVNPLSPLMPLLQTLTAPLLDPIRRILPRTAIDFSPLVLLIGAQILLMMVARLAYGIFGV
>NZ_AP014582.1|WP_003814930.1|4519123_4519801_+|histone-H1-like-DNA-binding-protein
MATAKKAAKKAVKKPAAKKAAAKKATPAKKAAVKKVAVKKVAAKKPAVKKVAAKKPAAKKVAKKAVAKKAVAKKPAAKKVAKKAVAKKAVAKKAVAKKAVAKKAVAKKAVAKKAPAKKAVAKKAVAKKAVAKKAVAKKAVAKKAVAKKAVAKKAPAKKAAAKKAPAKKAAAARKPAAKKPAAKKPAAKKAAPKKPATPPSTAAAPGAKTALNPAASWPFPTGGRP
>NZ_AP014582.1|WP_033452676.1|4517603_4518806_+|ribonucleotide-diphosphate-reductase-subunit-beta
MLNWEEENIATKPATSPAPAPAGGREAAPAVRAATGVFGDAALPTPTAPQHAASLGASDATAGRVKVADKRIINGETDVNQLVPFKYKWAWEKYLATCANHWMPQEINMSRDIALWKNPNGLTEDERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQFLLRQAFEEAIHTHAYQYIVESLDLDEAEIFNAYNEVPSIRAKDEFLIPFIDAIADPNFHTGTPEADQKLLKSLIVFACLMEGLFFYVGFTQILALGRQNKMTGAAEQYMYILRDESMHCNFGIDLINTIKLENPHLWTPEFREEIRELFRKAVELEYAYAEDTMPRGVLGLNAPMFKSYLRFIANRRCQQIGIEPLFPQEENPFPWMAEMIDLKKERNFFETRVIEYQTGGTLSWE
>NZ_AP014582.1|WP_003814928.1|4514654_4517582_+|ribonucleoside-diphosphate-reductase-subunit-alpha
MQTTIASVTRPTAVPPAQSETSTDPNSGQWASYNIIRRNGSVVGFEPSKIAIAMTKAFLAVNGGQGAASARVRELVEQLTAQAVSALVRNRPAGGTFHIEDVQDQVELALMRSGEHDVARAYVLYRERRAQERAAAAEVLEKSSPAAAQEPTLSVVDNGVRRPLDLAALRATIEAAGEGLTQYTDTEAILKETVKNLYDGVPVDEVFKSAILAARALVEKDPAYSQVTARLLLHTIRKEVLGEEVSQADMATRYAEYFPAFIQRGIEGGLLDAKLAEYDLERVAKALDGRRDLQFGYLGLQTLYDRYFLHVRGTRIELPQVFFMRVAMGLALREADREARAIEFYEILSSFDFMSSTPTLFNSGTLHSQLSSCYLTTVSDDLEGIYDAIKENALLAKYAGGLGNDWTPVRALRSHIKGTNGESQGVVPFLKVVNDTAVAVNQGGKRKGAVCTYLETWHLDIEEFLELRKNTGDERRRTHDMNTANWIPDLFMKRVMENGEWTLFSPSDCPDLHDKYGKAFEQAYAGYEAKVASGELKLFKKMPAVSLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNATEIAVCNLGSVNLVAHMKPSANGGYELDHDKLKRTIGVAMRMLDNVIDINYYAVDKARNSNERHRPVGMGIMGFQDCLHVMRVPYASQDAIDFADRSMEAVCYHAYWASSELAQERGRYQSYEGSLWSRGILPQDTLAMLREERGGNVDVDDSSSLDWDTLRSRIKEHGMRNSNCIAIAPTATISNIIGVSACIEPTFQNLYVKSNLSGEFTVVNDYLVRDLKKLGLWDEVMVADLKYFDGSLSRIDRVPSELRKLYATAFEVEPSWLVECASRRQKWIDQAQSLNIYMSGASGKKLDDTYKLAWQRGLKTTYYLRTLGATSAEKSTGRGGELNAVSAGDHGAGSAVSAAPVLPEPEIVGAVCTMRPGDPGFEECEACQ
>NZ_AP014582.1|WP_003814926.1|4510842_4514349_+|indolepyruvate-ferredoxin-oxidoreductase-family-protein
MDGTPAVDPHIDLDYQLGDNLTRTSGRVFLTGTQALVRMMLTQRRLDRDRGLNTAGFVSGYRGSPLGGVDMAMWKAGQALADNQVSFLPGINEDMAATAVMGTQQAGVRADRKVDGVFAMWYGKGPGVDRAGDALHHGNAAGASRHGGVLVVVGDDHTAVSSSIPHASEASLIGWHMPIVHPASIDEYETFALWGWALSRYSGAWVAFKAVSETVECGQSFVLEPPAAYEMPDDPELPAEQLEYTARDFLSPAVELRMHRRLRAVRAFARRHSLDRLVCAAPRATLGIVTVGKAHLDTMEALHRLGLDTVGAQAPVRIYKPGLTWPLDGPRLIEFAQGLRHILVIEEKGAVVESQIKDLLFNLPQRPSVAGKTGLDGAELIPAAGQLRPSLLAAPLAAWLRRAGHMPGGAAPAAFACPAPLSNDADGMRRRPYFCSGCPHSTSTKVPEGSQALAGVGCHYMAAWMDRDTGGLTQMGGEGADWIGLSPYIEMPHVFQNMGEGTYYHSGYLAIRQAVAARANITYKILFNDAVAMTGGQPVDGPISVPQICQQLRGENVARIVVTTDEPEKYRGVALGAGIDVHHRRDLDAVQRELRATPGVTVLIHDQTCAAEKRRRRKKNQFPDPPRRLLINSAVCEGCGDCGVQSNCLSVVPLETPYGRKRAIDQSSCNKDYSCVEGFCPSFVSVMGGKPRKSAAPAADHERLRARIARLPEPRPAPLEAPYRLLVAGMGGTGVITIGAIVSMAAHLQGLSAAVLDLTGLAQKGGTVVSHIRLAPSGTANGPVRLDWQQADAAILCDPVAAVAPDSLGALRRDHTRTTVNTYVAPVSDFTRNPDAPLRADALLAKIRHAAGEHVAALDAHAAAQALFGDSILSNMFMLGHAWQRGDVPLALAALARAIELNGVAVAANRAAFDAGRLAAHEPQSMAQALRPAAQVVQLHIPESFERAVERRVADLTAYQSAAYAQAYRDLVEQVAARERELAPAARAPRLAMAVARSLFKLMAYKDEYEVARLYTDDAFRAQLDSQFEGDYSLRLHLAPPLLARKDPRTGAPRKITLGPRTLTLMKALARLKGLRGTWFDPFGHTAERRMERALVAEYRATVIQLLAGLSVDRLAQAATIAALAETVRGYGHVKQASVRKYRDELERQLRRYQEPTGSPDVSLRQTA
>NZ_AP014582.1|WP_003814925.1|4510261_4510714_-|Lrp/AsnC-family-transcriptional-regulator
MDKTDIGILKALQEDGRASAQQLSETVGLSAAPVWRRVKALEANKVITGYSAQVDRSKVGLQGCMFAQISLERHSAGTVETFERSVRDAPEILECYAVTGDSDFLLKILVESPEAYDRFLHRFLFNLPGIRQTRTIVVLRELKHEVRLPL
>NZ_AP014582.1|WP_003814946.1|4524964_4525468_-|glycine-zipper-2TM-domain-containing-protein
MNYMHSPSVVAGRARRLLAVAAVAGSVAVLAGCANPSASSGVYTYGQAQREQIVRTGTVTGVRPITIQNDKSSGVGMVAGGALGGVAGNAVGGGTGRTIATVGGVILGALAGNAIENRAGKSSGYEITVRLDNGETRVVAQEADVPISVGQRVQVISGAGPTRVTPY
>NZ_AP014582.1|WP_003814947.1|4525641_4526583_-|carbohydrate-kinase-family-protein
MTAPVLVCGSMAFDTIAVFEGRFKEHILAERIQSLSVSFLVPAMRKEYGGCAGNIAYNLKLLGGQPVPVATVGEDAGEYLARLSGLGIDVSRIQVVPGTFTAQCFITTDLEDNQIAAFHPGAMEFSSGNDLSDAQAAWAIIAPDSKAGMFAHAERLHARGIPFIFDLGQAMPLFDGADLERMLKLAQALTVNDYEAGVVEQRTGRSLAEIASGLRAAVVTRGAHGATVMAGGQTIEVAPVQAQAVVDPTGCGDAHRAGLLYGLTSGWGWADSCRLGNLMGAIKIASRGPQNHAPSRSEIDALMRANYGIGLPD
>NZ_AP014582.1|WP_033452679.1|4526594_4527722_-|DUF3426-domain-containing-protein
MALTTRCPQCGAAFRVVADQLRVRNGLVRCGECATVFDGRACLVPAPDAGAPRAAAPPVPSAPPVPSAPPSDPPFDPPYAHRAASEPAAPATQAPPAVLRGRADMQRGDAPPVDEDEPDAMADGAPEDEADWDAAPRLESAEAGWRPILPRDPAHDDREPAFRIGRTATACAAADAEDAVQVPGEVRTRYSNAVDSGRTPPEFLDDDRIQARQLVRRLWAYACVLGVLALAAQLVYVYRGAIAGAAPALRPVLEQACVPLQCSVGHARRIERISITSSSLRPAAGAAQGDDARTRLTLNVVLRNRYDRPQEWPALVLDLTDISDTVVARKIILPQDYLPSQAGPAFAAGSEINLAIPVEVAGLQVNGYQLDKFFP
>NZ_AP014582.1|WP_003814950.1|4527747_4528671_-|50S-ribosomal-protein-L11-methyltransferase
MRELVLNCREAQADALSDALLEAGVLSVSVEDADLGTEAERPLFGEPGTEPQVQAWERNCVVALLPDGADPAQILEQAIAAAGLDPALAHGWSLREVPDADWVRLTQSQFGPIPISERLWIVPSWHRDDPAVPGLVPDAARDAIHIELDPGLAFGTGSHPTTHLCLAWLEAELPAGARLLDYGCGSGILAIAARKLGAGETVAVDIDPQAVQSTVDNAEVNQVRLQAMLPDALPAGEFQVVVANILSNPLKVLAPMLAGRVAPGGHLVLSGVLERQADEVAAAYAPWLTMSVWRERDGWVCLHGVKA
>NZ_AP014582.1|WP_003814951.1|4528689_4530036_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit
MFEKILIANRGEIALRIQRACRELGIKTVVVHSEADRTAKYVRLADESVCIGPAPSRESYLNMPALISAAEVTDAEAIHPGYGFLAENADFAERVEKSGFVFIGPRPETIRQMGDKVSAKRAMIEAGVPVVPGSEGALPDDPQEILRIAREVGYPVIIKASGGGGGRGMRVVYTEAALLNAVNMTRSEAGAAFNNPEVYLEKFLENPRHVEIQVLADGGRNAVWLGERDCSMQRRHQKVIEEAPAPGIPRRLIERIGDRCADACRKMGYRGAGTFEFLYENGEFYFIEMNTRIQVEHPVTELITGVDVVQQQILIAAGEKFTLRQRDIQFKGHALECRINAEDPFRFVPSPGRITNWHVPGGPGVRIDSHAFNGYFVPPNYDSMIAKVITYGDTREQALARMRIALSEMVVEGISTNIPLHRELLQDARFIEGGTSIHYLEHKLAQRP
>NZ_AP014582.1|WP_033452681.1|4530045_4530495_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein
MDLRKLKTLIDLVAESGIAELEITEGEGKVRIVKFSQALQPVAYHMPEAVAPAAAPAAAAVPAAEAAPAAPQGHVVKAPMVGTFYRAPNPGAAPFVDVGQSVKEGDPLCIIEAMKLLNEIEADKAGVIKEILVENGEPVEYGQPLFIIG
>NZ_AP014582.1|WP_003814953.1|4530584_4531019_-|type-II-3-dehydroquinate-dehydratase
MAQRILVLHGPNLNLLGTREPHIYGSLTLAQIDQGLAALAGQLGVALTSWQSNHEGALVERIQAAAADGTDFIIINAAAYTHTSVAIRDALAAVAIPFIEVHLSNLYKRDSFRQHSYLSDLAIGLITGLGADGYEAALRYAARH
>NZ_AP014582.1|WP_003814954.1|4531097_4531646_-|TlpA-family-protein-disulfide-reductase
MNRRLFLYAGVAAAAAASGGYFLAERRNARPAPSAAAPAEGAGDPLAQLRQLALPDLQGTPRKLADWGGQPLVVNFWATWCAPCVKEMPELDALQKKYPQVRFVGIGVDTADNMRKFVEKIPVSYPLLVMGAGAIDTLRSLGNPSGGLPFTLLLSADGSMKRKILGQIVYDDLDRSVAGLSA
>NZ_AP014582.1|WP_003814955.1|4531728_4533099_+|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase
MHLHILGICGTFMGGLALIARSAGHKVTGCDAGVYPPMSTQLAEQGIELIEGFGADQLALAPDLFVIGNVVSRGNPLMEAILDSGARYISGPQWLGEHILPGAHVLAVAGTHGKTTTSSMLAWILQCAQRQPNFLIGGVAPDLQVSARYAPGARPFVIEADEYDTAFFDKRSKFVHYRPRTAILNNLEYDHADIFPDLAAIETQFHHLVRTVPSNGQLVLPTDAPALERVLERGCWTPVARFGPGGQWQAGPADEQGAFEVSVDGRDAGTVRWTLGGEHNRRNALAALAAARHAGVAPAEGIEALSRFGGVKRRMELRGTVNGIRVYDDFAHHPTAIATTIEGLRRQVGAARILAVLEPRSNTMKLGTMAARLPEALAGADLVFCFGDHAGKHALGWDPARVLAPLGERAAGYDDLPALVRAVAAAARPGDHVLVMSNGGFGGVHGKLLDALAQPR
>NZ_AP014582.1|WP_003814956.1|4533109_4533703_+|alpha/beta-fold-hydrolase
MPILYLHGFRSSPDSFKARLLAQAMHQRGLAGQWQCPQLPASPRQAAELALALAREQLAGQQDPRRLTVIGSSLGGYYATWLAERLGCQAVLLNPAVQAARDLATQVGEHRMYHSDAPFHFLPEYVEELRALYADPLTHPERYFLVAATGDEVLDWREMRDRYPGCRQRIVQGGDHGLSDFPRWMPEVLEFALGSPH

Crispr_ID: NZ_AP014582_10

• CRISPR_ID: NZ_AP014582_10
• CRISPR_location: 4667918-4668001
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP014582_10

Consensus_repeat	Method
GGTGCCTGTCCCCGCGGGGACAG	CRISPRCasFinder

spacers of NZ_AP014582_10

>10.1|4667941|38|NZ_AP014582|CRISPRCasFinder
ATACCGTCTTGGCCGTCAAGCGTTCTGGCGTATGACGG

CRISPR arrays and Neighbor proteins around NZ_AP014582_10

CRISPR arrays

The CRISPR arrays of NZ_AP014582_10

>merge|NZ_AP014582|10|4667918-4668001|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAGATACCGTCTTGGCCGTCAAGCGTTCTGGCGTATGACGGGGTGCCTGTCCCCGCGGGGACAG

>NZ_AP014582|10|10|4667918-4668001|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAG	ATACCGTCTTGGCCGTCAAGCGTTCTGGCGTATGACGG
GGTGCCTGTCCCCGCGGGGACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014582.1|WP_003815186.1|4664530_4665469_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	unknown	unknown	gnl|CDD|223390
NZ_AP014582.1|WP_010927137.1|4665535_4666069_+|YraN-family-protein	unknown	unknown	gnl|CDD|173148
NZ_AP014582.1|WP_003815194.1|4670007_4670754_+|pyrimidine-5'-nucleotidase	unknown	unknown	gnl|CDD|319791
NZ_AP014582.1|WP_003815196.1|4671591_4673085_+|DASS-family-sodium-coupled-anion-symporter	unknown	unknown	gnl|CDD|279307
NZ_AP014582.1|WP_003815183.1|4662145_4663018_+|RNase-adapter-RapZ	unknown	unknown	gnl|CDD|235450
NZ_AP014582.1|WP_010927138.1|4670803_4671379_+|nucleoid-occlusion-factor-SlmA	unknown	unknown	gnl|CDD|181894
NZ_AP014582.1|WP_003815185.1|4663961_4664534_-|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl|CDD|223427
NZ_AP014582.1|WP_003815202.1|4677275_4677839_-|rod-shape-determining-protein-MreD	unknown	unknown	gnl|CDD|274574
NZ_AP014582.1|WP_003815203.1|4677825_4678710_-|rod-shape-determining-protein-MreC	unknown	unknown	gnl|CDD|237560
NZ_AP014582.1|WP_003815190.1|4666667_4667411_+|BON-domain-containing-protein	unknown	unknown	gnl|CDD|182907
NZ_AP014582.1|WP_003815198.1|4674176_4675313_-|rod-shape-determining-protein-RodA	unknown	unknown	gnl|CDD|274033
NZ_AP014582.1|WP_003815182.1|4661221_4661974_-|c-type-cytochrome	unknown	unknown	gnl|CDD|225418
NZ_AP014582.1|WP_003815197.1|4673095_4674151_+|Ldh-family-oxidoreductase	unknown	unknown	gnl|CDD|376860
NZ_AP014582.1|WP_003815181.1|4659924_4661211_-|cytochrome-c	unknown	unknown	gnl|CDD|365823
NZ_AP014582.1|WP_003815191.1|4667407_4667899_+|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NZ_AP014582.1|WP_003815192.1|4668055_4668844_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224381
NZ_AP014582.1|WP_033446211.1|4666077_4666671_+|phosphoheptose-isomerase	unknown	unknown	gnl|CDD|237567
NZ_AP014582.1|WP_003815193.1|4669105_4670008_+|acetylglutamate-kinase	unknown	unknown	gnl|CDD|234869
NZ_AP014582.1|WP_003815184.1|4663014_4663965_+|septal-ring-lytic-transglycosylase-RlpA-family-protein	unknown	unknown	gnl|CDD|223868
NZ_AP014582.1|WP_003815201.1|4675309_4677262_-|penicillin-binding-protein-2	unknown	unknown	gnl|CDD|274573

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP014582.1|WP_003815186.1|4664530_4665469_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	gnl|CDD|223390	COG0313, COG0313, Predicted methyltransferases [General function prediction only].	9.54075e-109
NZ_AP014582.1|WP_010927137.1|4665535_4666069_+|YraN-family-protein	gnl|CDD|173148	PRK14685, PRK14685, hypothetical protein; Provisional.	1.2057e-90
NZ_AP014582.1|WP_003815194.1|4670007_4670754_+|pyrimidine-5'-nucleotidase	gnl|CDD|319791	cd02604, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to Saccharomyces cerevisiae Phm8p and Sdt1p. This family includes Saccharomyces cerevisiae Phm8p (phosphate metabolism protein 8) and Sdt1p (Suppressor of disruption of TFIIS). Phm8p participates in the ribose salvage pathway, it catalyzes the dephosphorylation of nucleotide monophosphates to nucleosides, its preferred substrates are nucleotide monophosphates AMP, GMP, CMP, and UMP. Phm8p is also a lysophosphatidic acid phosphatase, dephosphorylating lysophosphatidic acids (LPAs) to monoacylglycerol in response to phosphate starvation. Sdt1p is a pyrimidine and pyridine-specific 5'-nucleotidase; it is an NMN/NaMN 5'-nucleotidases involved in the production of nicotinamide riboside and nicotinic acid riboside, and is a pyrimidine 5'-nucleotidase with high specificity for UMP and CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.14842e-46
NZ_AP014582.1|WP_003815196.1|4671591_4673085_+|DASS-family-sodium-coupled-anion-symporter	gnl|CDD|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	2.68833e-115
NZ_AP014582.1|WP_003815183.1|4662145_4663018_+|RNase-adapter-RapZ	gnl|CDD|235450	PRK05416, PRK05416, RNase adapter RapZ.	1.18739e-149
NZ_AP014582.1|WP_010927138.1|4670803_4671379_+|nucleoid-occlusion-factor-SlmA	gnl|CDD|181894	PRK09480, slmA, division inhibitor protein; Provisional.	1.59741e-107
NZ_AP014582.1|WP_003815185.1|4663961_4664534_-|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl|CDD|223427	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	7.98182e-54
NZ_AP014582.1|WP_003815202.1|4677275_4677839_-|rod-shape-determining-protein-MreD	gnl|CDD|274574	TIGR03426, shape_MreD, rod shape-determining protein MreD. Members of this protein family are the MreD protein of bacterial cell shape determination. Most rod-shaped bacteria depend on MreB and RodA to achieve either a rod shape or some other non-spherical morphology such as coil or stalk formation. MreD is encoded in an operon with MreB, and often with RodA and PBP-2 as well. It is highly hydrophobic (therefore somewhat low-complexity) and highly divergent, and therefore sometimes tricky to discover by homology, but this model finds most examples. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	7.62373e-19
NZ_AP014582.1|WP_003815203.1|4677825_4678710_-|rod-shape-determining-protein-MreC	gnl|CDD|237560	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional.	9.0892e-90
NZ_AP014582.1|WP_003815190.1|4666667_4667411_+|BON-domain-containing-protein	gnl|CDD|182907	PRK11023, PRK11023, divisome-associated lipoprotein YraP.	1.20064e-42
NZ_AP014582.1|WP_003815198.1|4674176_4675313_-|rod-shape-determining-protein-RodA	gnl|CDD|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	3.23854e-160
NZ_AP014582.1|WP_003815182.1|4661221_4661974_-|c-type-cytochrome	gnl|CDD|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	1.39738e-12
NZ_AP014582.1|WP_003815197.1|4673095_4674151_+|Ldh-family-oxidoreductase	gnl|CDD|376860	pfam02615, Ldh_2, Malate/L-lactate dehydrogenase. This family consists of bacterial and archaeal Malate/L-lactate dehydrogenase. L-lactate dehydrogenase, EC:1.1.1.27, catalyzes the reaction (S)-lactate + NAD(+) <=> pyruvate + NADH. Malate dehydrogenase, EC:1.1.1.37 and EC:1.1.1.82, catalyzes the reactions: (S)-malate + NAD(+) <=> oxaloacetate + NADH, and (S)-malate + NADP(+) <=> oxaloacetate + NADPH respectively.	1.11307e-125
NZ_AP014582.1|WP_003815181.1|4659924_4661211_-|cytochrome-c	gnl|CDD|365823	pfam00034, Cytochrom_C, Cytochrome c. The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.	4.18466e-10
NZ_AP014582.1|WP_003815191.1|4667407_4667899_+|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.58284e-41
NZ_AP014582.1|WP_003815192.1|4668055_4668844_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl|CDD|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.17353e-136
NZ_AP014582.1|WP_033446211.1|4666077_4666671_+|phosphoheptose-isomerase	gnl|CDD|237567	PRK13936, PRK13936, phosphoheptose isomerase; Provisional.	6.68272e-126
NZ_AP014582.1|WP_003815193.1|4669105_4670008_+|acetylglutamate-kinase	gnl|CDD|234869	PRK00942, PRK00942, acetylglutamate kinase; Provisional.	1.71108e-158
NZ_AP014582.1|WP_003815184.1|4663014_4663965_+|septal-ring-lytic-transglycosylase-RlpA-family-protein	gnl|CDD|223868	COG0797, RlpA, Lipoproteins [Cell envelope biogenesis, outer membrane].	3.79567e-55
NZ_AP014582.1|WP_003815201.1|4675309_4677262_-|penicillin-binding-protein-2	gnl|CDD|274573	TIGR03423, pbp2_mrdA, penicillin-binding protein 2. Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0

Protein sequences

>NZ_AP014582.1|WP_003815191.1|4667407_4667899_+|TlpA-family-protein-disulfide-reductase
MKKIALVLIIAVAAGIGGWFMWRPAQTAPDVAFTTLEGQKITMQDLRGKVVLVKFWATSCVTCVKQMPDNIANYNQYHPQGYETIAVAMNYDPPNYVLNFAQTRKLPFPVALDTSGELAQAFGNVRLTPTAFLIDKQGQIIKRYLGEYDKAEFQATVQKALAG
>NZ_AP014582.1|WP_003815190.1|4666667_4667411_+|BON-domain-containing-protein
MMPDAKTAARPLLLAAALSAAALTLSACAPLVIGGAAATTAVVVTDRRTSGVQLEDQNIAFKAESQIAQKLGNTARVNAMVYGGHVLLTGDAPTEEAKAQATAIAQSIENVKAVTNQLTVGPAADFSTRSNDTWLTSKVKTALINTKYVPSGTISVTTSRGVVYLMGKVTQAEGDYAANAAAGVGGVARVVKLFETISREEAIRLSGSGTKSGEGSSDGTAAQKAPIESGAAPAGSGSNGVEAIPIK
>NZ_AP014582.1|WP_033446211.1|4666077_4666671_+|phosphoheptose-isomerase
MDMTSRMTSHFRDAMALCEQSADALAAPLAAAVDLLFAALANNGRILACGNGGSAADAQHFIAELVGRFERERLPLAGIALNTDTSIMTAVGNDYGFDEIFERQVHALGQPGDVLVAISTSGNSPNVVRAMETAREREMHVIALTGKGGGVMGELITPHDVHLCVPHDRTMRIQEVHIILLHALCDGIDALLLGDTE
>NZ_AP014582.1|WP_010927137.1|4665535_4666069_+|YraN-family-protein
MTDTATRLAFARAAQAQRRLHRRPPASPRARPGARDGGSPTQRRGQAYESAALRWLARQGLRPLARNLRCRAGEIDLAMRDGEVLVLVEVRVRAHAGYGGAAASIGASKQGRLARAAALLLPVLLRRHWPGAPPPVRFDVVAFEAGRPHWLRGAFWLAEHAPAQGRRGQDAQGWRVR
>NZ_AP014582.1|WP_003815186.1|4664530_4665469_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase
MNQDVLSPAPGDAWSRVADRVAAQHWPAATLYVIATPIGNLGDLGLRAWQALVRADVIAAEDTRASRTLLDAWGVSTPLMAAHRHNEASAAQAICERLAQGQRVALVSDAGAPAVSDPGARIVRAVREAGYAVVPVPGPSAVIAALMGSGATSDENPAFAFAGFPPAKAVARQRWLRQWCALPAPVVMFESPHRLAATLADLREAGGPARLLTVARELTKRFEEIATMPLGEAADWLAADAHRGQGEFVLIVHQAPGAQDDEADPADPRTDALLDALLESLSVRDAARVAAKVTGLARDVLYARALARKEQP
>NZ_AP014582.1|WP_003815185.1|4663961_4664534_-|methylated-DNA--[protein]-cysteine-S-methyltransferase
MNPPSEQATDILYCDTDTPLGPMRLAARGQALCGAWFVDQRDCPAAAGWTPDAAHPALRQAAAELEQWFAGRRRAFEVDMQPEGTPFQRQVWQALLELPFGATISYGELARRVGRPKAARAVAGAVGRNPISILIPCHRIIGHDTSLTGFGGGLPRKQALLAHEGHRYLSRAARARRVSTTQMELPFGAA
>NZ_AP014582.1|WP_003815184.1|4663014_4663965_+|septal-ring-lytic-transglycosylase-RlpA-family-protein
MIRSRPLALLSTLLLALAIAGCSTPGKKRGGYYKDDGPDANPPSNLDNVPDATPRLEPLASGPNRPYVVFGKRYVPDTSERPFRQQGLASWYGKKFHGNSTSNGESYDMYAMTAAHPTMPIPSYARVTSKINGRTVIVRVNDRGPFHSDRIMDLSYVAAHKLGIIGPGSGPVTVERILPAEILAMNGGAAAPRPGPASATGPLPVAAPSAAAAVELHPATQLASNAPTPPRPATGAGSGIYLQLGAFSQPANAESLVSRINGQLDPASGIPPAVVEQANNLYRVRIGPYATREAALGAVQPVADRTGILPSLSATP
>NZ_AP014582.1|WP_003815183.1|4662145_4663018_+|RNase-adapter-RapZ
MLRVVLITGISGSGKSVALRLLEDAGFTCIDNLPVRFLAEFIANARDDAMERVAVAIDVRSPGELAELPDVITASRAMGTSLSVIFLDANTDTLVQRYSESRRRHPLTDRLARGGKTPSLAECIALERELMAPLRDQEHVIDTSDLTPGQLRAWIRDLIQADRPPLVLTFESFAYKRGVPSDADLMFDVRCLPNPYYDRTLRPLTGRDEPVATWLGGFDIVTQMIDDIAAFIRRWLPQYTQDTRNYLTVAIGCTGGQHRSVYVVEQLARRFSDHDPLLVRHRTQLPDDPA
>NZ_AP014582.1|WP_003815182.1|4661221_4661974_-|c-type-cytochrome
MLAFKSDLRIAMRAWRAACGVLAAAAGMLAMSQAVAQGEAALRPDTMAARVAACTACHGEQGRAGPDGYYPRLAGKPQDYLYHQLLNFRDARRQYPPMAHLLNGLPDAYLREMAAYFAGQDVPYPPPARVEASAALVERGRLLVREGDPARAIPSCASCHGASLAGVAPAIPGLLGLPRDYLVAQIGSWQNGLRRAAEPDCMAQVSLKLTPEDIGAVSAWLAGQPVGHPYTPQPAGSLTLPLECGSQAGH
>NZ_AP014582.1|WP_003815181.1|4659924_4661211_-|cytochrome-c
MKIIKRVLVVAILALLAAVATLYWLGTRDHVPAGPQAAPATGSADELVEQGRYLARAGNCMACHTARGGQAYAGGTPIPTPFGTLYGPNITPDAETGIGGWSADDFWQALHNGKGPGGRLLYPAFPYTEYTRMTRADADALYAFLRTVEPVRQASRPHELASPYDQRLLLAAWRALYFEPGGPQADPGQSLQWNRGRYLTEGLGHCAACHTPRNSLGATRAAEALGGGMIDGLGWYAPPLTGQPGTGLGDWSAQDIAALLTTGIAPHSTVAGPMAEVVLGSTQYLSGDDALAIGTYLKSLPAAAPPPARRGAPSATVMELGGKLYGQHCAQCHQADGKGSFPAWPALAGNPSVIAAEPANVIRMVLDGGFAPATAANPRPHGMPPFAQALPDNDIAMLVSYVRNSWGNQAGAVTPLDVKRTRESGAGR
>NZ_AP014582.1|WP_003815192.1|4668055_4668844_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MRMNFVRSALLASAFLLAGGAAQAEKLVVGATQVPHAEILEVVKPALAKEGVELDIKVFTDYVQPNLQLADKQLDANFFQHQPYLDTFNKDRKTNLVSVGLVHVEPFGGYSKKIKSLAELKDGATIAIPNDPSNSGRALLLLQKQGLLKLKDPSNIVATPIDIAENPKKLKFRELEAAMLPRSLDDLDLALINTNYALEAGLVPTRDALFIEGADSPYANLVAARPDNKDAPAVKKLVNALHSEAVRKFIIEKYKGAVVPAF
>NZ_AP014582.1|WP_003815193.1|4669105_4670008_+|acetylglutamate-kinase
MTDTPDPAAVLSPAVKAAVLSEALPYIRRFHGKTIVVKYGGNAMTEERLQRSFAHDVVLLKLVGLNPVVVHGGGPQIDDALRRIGKQGTFVQGMRVTDAETMEVVEWVLGGQVQQDIVMMINEVGGKAVGLTGKDGMLIQATKKLMVNKDDPSQPLDIGFVGDITRVEPAVVKALQDDQFIPVISPIGYGEDGTAYNINADVVAGKMAEVLGAEKLLMMTNTPGVLDKGGKLLRSLSAQTIDELFADGTISGGMLPKISSSLDAAKNGVNSVHIVDGRVPHCLLLEILTDQGVGTMISSH
>NZ_AP014582.1|WP_003815194.1|4670007_4670754_+|pyrimidine-5'-nucleotidase
MQARRYLLRPAARLRRSRRIATAAPERLWLFDLDNTLHDTSHAIFPLIDRGMTEAVAETLAVDEATANRLRAEYWRRYGATVIGLVRHHGVDADAFLHRSHNFEVAPLVRAETALADKLRRLPGRKVLLTNAPLHYARAVLRHLGLLRQFDSIWAIEQMRMHGQFRPKPSDALLRYVLAREGVPAARAVLIEDTLDNLRSARRVGLRTVHVFHPGTPFARGHRQRPGYVDLRVNSVSDLLLRRRPLRG
>NZ_AP014582.1|WP_010927138.1|4670803_4671379_+|nucleoid-occlusion-factor-SlmA
MASKPGERKTQILHTLAEMLEQPHAARITTSALAARMQVSEAALYRHFASKAQMFEGLIEFIETSIFTVVNQIAVSEPYGMGQARKTVAMLLAFAERNRGITRVLTGDALVTEDNRLQERINHINDRIEASLKQCLRVAVSDGALPADANIAAHASLLTHLVLGRWLRYAQSGWRVAPTTHLEEHLRLALG
>NZ_AP014582.1|WP_003815196.1|4671591_4673085_+|DASS-family-sodium-coupled-anion-symporter
MTAPAAVPAPQSPPKVKIPIGLIAGIIAMVVVLLLPLPAELPPAGHRMLAILAFAVVVWITEAVSYEASAIMITTLMAFLLGTAPNVKNPDVLYGTSAAISMALTGFSNSALALVTGALFIAAAMTFTGLDKRIALVTLARVGTSTRRILLGAIAVTIVLSLVVPSATARSAAVVPIMLGVIAAFGVDKRSNIAAGIMIIVAQATSIWNVGIQTAAAQNLLTVGFMDKMLGERVAWSDWLIAGVPWSLLMSAVLIFVVLRLLPPESDAIAGGKEAVEASLRELGPMTSAQKRLMLVSIMLLLFWSTEGKLHKFDTTSTTYFGLVLLMLPRFGVMTWKDVQTRIPWGTVIVFGVGISLGTALLTTQAGQWLGAQVVAHTGLDHLGPLGIFAILSAFLILIHLGFASATALTSAMLPILIAVLQTLPGDFNRLGMTMLLGFVVSYGFILPINAPQNMVALGTETFTAKQFAKVGIVLTIVGYLLMLLMSVTYWRWLGWM
>NZ_AP014582.1|WP_003815197.1|4673095_4674151_+|Ldh-family-oxidoreductase
MKLSIAQAIAFGQRLLAAQGVPDDIARDVAEHLVESDRVGYTSHGLSILPNYRRVLAEGFVKADGRARLLNDRGAMLAFDGDNGFGQHVGKAVMQQAIERARQYGQCIVTLRRTHHLGRMGYYGEMAAEAGLILLAFTNVVNRPPTVAPYGGAQACLTTNPLCFAGPLPGGRPPFLVDMATSSIAVNKARVLAARGEPAPDGALIDAQGNPTNDPNALFADPPGALLPFGGHKGYAMGLVAELLAGVLSGGGTIQPEHPRNGVATNNMFAILLDPQVDFNADWRTQEVGAFIDYLHACPPQPGVDRVQYPGEYEAMNRARHAEAIEFEGAIWDSLAKLAQDLGAADALPRA
>NZ_AP014582.1|WP_003815198.1|4674176_4675313_-|rod-shape-determining-protein-RodA
MKRLGLILLRVFTAFDWPLLLILILFTLLGLTVMHSAVGSTDWRFAEQSRNFLIAFAAMWAMALVPPNTLMKLALPFYVLGVILLLGVEFFGETSKGATRWLNLGVTRIQPSEMMKIAVPMMLAWYFQRHDGAVRIRDFFVAAAMLAAPFVLIVLQPDLGTALLVFGAGFFVIYFAGLSFKLLVPCLLAGIIAIGTLIYYEDQLCEPEVDWVVLHDYQKHRVCTLLNPSSDPLGKGFHTIQSMIAVGSGGLYGKGYMQGTQTHLDFIPERTTDFIFAVYAEEFGLYGGVALLVLYGLFMARGLAIASRASSQFGRLLAGAITMMMFIYVFVNVGMVTGILPVVGVPLPFMSYGGTALLTMGIACGILMSISRRRPAPA
>NZ_AP014582.1|WP_003815201.1|4675309_4677262_-|penicillin-binding-protein-2
MFEFKKTGQQQKQRFRLRAWVGGLFALACFGVLAGRFWYLQVDRYEGFSERADRNRIAVVPIPPRRGEILDRNGEVLARNYRTYTLEVVPAQAGNLDQLFDRLARVVYISPSDQRRFKRRVGESSRYASLQLRNNLNDTEAAWFSAHSFEFPGVELRARWVREYPQGEAAAHVVGFIGRIAENDIEELDKAGQLGNYRGTDVIGKKGIEKTWEAALHGRTGLEEVEVTAGGRPMRTLRRIDPVPGSDIMLSIDLELQKLAEQAFEGRRGALVALDPDTGEVLAFVSQPSFDPNLFVDGIDVENWRRLNESPDHPLINRPLYGTYPIGSTYKPFVALAALELGKRRATDRMPDPGYFEFGGQKFRNAGGAAYGMTDMHRAIVVSSDTYFYSLGPEIGVNALHDFSKQFGFGQITGIDLEGEKAGVLPSTEWKRKAYKDRDRQRWYAGETISVAVGQGYNSFTLLQLAQATSTLANSGLYRRPHLVHAIRDSRSGSVNPTEIAPDYRIPLKQENVDVIKRAMADVVRAGTARRAFAGAPYQAAGKTGTAQVFSLRGGQYRASAIDERLRDHALFMGFAPVEQPRIAVALIVENAGWGASAAAPIARTLFDNWLGRADAPSVVRAGAKPVAAEPEAAALELGATDGPMQERRQ
>NZ_AP014582.1|WP_003815202.1|4677275_4677839_-|rod-shape-determining-protein-MreD
MERTKVSVPARRKLGTPSNVEPERLARPAHGVFVWGTVLLVWLLSLLPWRQWPGSPDVLVLVIAFWCVHEPRRVGLLTAFVFGLLLDVHDAGLLGGHALSYTLTAYGAIALHRRLQRFDLWSQAMHMLPVFFLAQLVTQIILAWLAGKWPGWQWAVSVGLTVAIWPLAGWVLHMPQRRYDDVESSAV
>NZ_AP014582.1|WP_003815203.1|4677825_4678710_-|rod-shape-determining-protein-MreC
MQRQATPPLFRRGPPAEVRLAVLVILALALLIVDSQLRVLEPVRRAVSVALYPFQRAVMAPRDLVQQVDEWINAASLIRSENEALQRQRIELAQVATHAAQLAAENAQLRRLLGVTDTVAQSAVVVEVLYEPPNAFHQRLVFNKGAKSGLAPGMPVIDEGGVVGQIVRVTPMTAEAALVTDERVSIPVQVLRNGLRLIAFGANTPGVIEVRYLAANADIKVGDTIVTSGVGGLFPAGLPVAKVASVERDTASGFARALGEPLAHPERYRHFLVLQVDVDQAESNRQEADVDGAD

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_AP014582_3	3.1|2172813|50|NZ_AP014582|CRISPRCasFinder	2172813-2172862	50	NZ_AP014582.1	1481367-1481416	0	1.0
NZ_AP014582_3	3.1|2172813|50|NZ_AP014582|CRISPRCasFinder	2172813-2172862	50	NZ_AP014582.1	2330030-2330079	0	1.0
NZ_AP014582_3	3.1|2172813|50|NZ_AP014582|CRISPRCasFinder	2172813-2172862	50	NZ_AP014582.1	2330113-2330162	0	1.0
NZ_AP014582_3	3.1|2172813|50|NZ_AP014582|CRISPRCasFinder	2172813-2172862	50	NZ_AP014582.1	2330196-2330245	0	1.0
NZ_AP014582_3	3.1|2172813|50|NZ_AP014582|CRISPRCasFinder	2172813-2172862	50	NZ_AP014582.1	2330279-2330328	0	1.0
NZ_AP014582_3	3.1|2172813|50|NZ_AP014582|CRISPRCasFinder	2172813-2172862	50	NZ_AP014582.1	2330362-2330411	0	1.0
NZ_AP014582_3	3.1|2172813|50|NZ_AP014582|CRISPRCasFinder	2172813-2172862	50	NZ_AP014582.1	1436784-1436833	1	0.98
NZ_AP014582_3	3.1|2172813|50|NZ_AP014582|CRISPRCasFinder	2172813-2172862	50	NZ_AP014582.1	1436867-1436916	1	0.98
NZ_AP014582_9	9.1|4524804|33|NZ_AP014582|CRISPRCasFinder	4524804-4524836	33	NZ_AP014582.1	3955000-3955032	1	0.97

1. spacer 3.1|2172813|50|NZ_AP014582|CRISPRCasFinder matches to position: 1481367-1481416, mismatch: 0, identity: 1.0

agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	CRISPR spacer
agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	Protospacer
**************************************************

2. spacer 3.1|2172813|50|NZ_AP014582|CRISPRCasFinder matches to position: 2330030-2330079, mismatch: 0, identity: 1.0

agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	CRISPR spacer
agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	Protospacer
**************************************************

3. spacer 3.1|2172813|50|NZ_AP014582|CRISPRCasFinder matches to position: 2330113-2330162, mismatch: 0, identity: 1.0

agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	CRISPR spacer
agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	Protospacer
**************************************************

4. spacer 3.1|2172813|50|NZ_AP014582|CRISPRCasFinder matches to position: 2330196-2330245, mismatch: 0, identity: 1.0

agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	CRISPR spacer
agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	Protospacer
**************************************************

5. spacer 3.1|2172813|50|NZ_AP014582|CRISPRCasFinder matches to position: 2330279-2330328, mismatch: 0, identity: 1.0

agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	CRISPR spacer
agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	Protospacer
**************************************************

6. spacer 3.1|2172813|50|NZ_AP014582|CRISPRCasFinder matches to position: 2330362-2330411, mismatch: 0, identity: 1.0

agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	CRISPR spacer
agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	Protospacer
**************************************************

7. spacer 3.1|2172813|50|NZ_AP014582|CRISPRCasFinder matches to position: 1436784-1436833, mismatch: 1, identity: 0.98

agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	CRISPR spacer
agccccctcggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	Protospacer
********.*****************************************

8. spacer 3.1|2172813|50|NZ_AP014582|CRISPRCasFinder matches to position: 1436867-1436916, mismatch: 1, identity: 0.98

agcccccttggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	CRISPR spacer
agccccctcggggggcagcaagcccgcacagcgggcgcagcgtgggggcc	Protospacer
********.*****************************************

9. spacer 9.1|4524804|33|NZ_AP014582|CRISPRCasFinder matches to position: 3955000-3955032, mismatch: 1, identity: 0.97

gcctgcaagatttcatggcatctgcccgtgcgt	CRISPR spacer
gcctgcaagatttcatggcgtctgcccgtgcgt	Protospacer
*******************.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP014582_7	7.1|3453496|28|NZ_AP014582|CRISPRCasFinder	3453496-3453523	28	NZ_CP035000	Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence	479490-479517	6	0.786
NZ_AP014582_7	7.1|3453496|28|NZ_AP014582|CRISPRCasFinder	3453496-3453523	28	NZ_CP045303	Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence	2432-2459	6	0.786

1. spacer 7.1|3453496|28|NZ_AP014582|CRISPRCasFinder matches to NZ_CP035000 (Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence) position: , mismatch: 6, identity: 0.786

ataccgtcttggcaggccagcgggacgg	CRISPR spacer
cgaccgtcttggcgggcgagcgggacaa	Protospacer
  ***********.*** ********..

2. spacer 7.1|3453496|28|NZ_AP014582|CRISPRCasFinder matches to NZ_CP045303 (Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

ataccgtcttggcaggccagcgggacgg	CRISPR spacer
gcccagtcctggcaggccagcgggatgg	Protospacer
.. * ***.****************.**

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	3111194 : 3119260	9	uncultured_Mediterranean_phage(28.57%)	tRNA	NA
DBSCAN-SWA_2	3616141 : 3638511	29	Pseudomonas_phage(18.18%)	tail,terminase	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_AP014582|3111194:3119260|DBSCAN-SWA
GTCATCGCGGCGGCAGATACTGCATCGGGTCGACCGGCGTGCCCTGGCGGCGGATCTCGAAATGCAGGCGCGGCGACGTGGTGTCGGTCTCGCCGATCTCGGCGATCTTGGCCCCGCGCTTGACGTTCTGGCCGGTCTTGACCAGCAGCGCGCGGTTGTGCGCATAGGCCGTGATGAAGCCGTTCTGGTGATTGATGATGATCAGGTTGCCCAGGCCGCGCACGCCATTGCCGCTGTACATCACCTTGCCATCGGCCGCCGCGATCACCGGATCGCCCAGCGAGCCGGCCAGGTCGATGCCCTTGGTGTTGCTGTTGAAGGTCTGCAGGATGGCGCCATTGGCCGGCCAGCCCCAGTTGATGACGGCGGCATCGGCCGCGCGCGCGGGCTTGGGATCGGGCACCGTTGCCGCGGGCGGGGTGGTGGCCCCGCCGGTTTCGCCGCCGGCGCCGGCTTCCATGCCGCCGGCCGGCGTTTCGGCGCTTCCCTGGTCCAGCGGCTTGGGTTGCGGCTTGGAGGAGGTCACCGGCGTGGTCTGCGCGCCGCCGGCGCCCGAGCTCGACAGGCGCAGCACCTGGCCGACACTGATCTGGTTGGGATCGGTGAGGTTGTTCCAGCGCTTGAGGTTTTCGATATCGACATTGTTGGCGCGCGCGATCTTGTAGAGCGTATCGCCAGGCTTGACGACATAGCTGCCGTCGGTCGGGCCGGAGGCGCCGGGCTGTCCGGTGAGGTCGACCACGGGCGCGCGCGGGCCCTTCGAGGCGCAGCCGGCCAGCAAGGCGATGGCCAGCACGCCCGCCCAGAGAACGGGTCGGGAAGCGGCGGCGGCGGATGCGCCAGCCACGGATTGGGATTCGGTCAGTTGCAACTGCCCGTTGAGCATACGATTCTCCTGTTTGCTCAAGATTGTATTCCGGCCCTGAGGGGCACAAAACGTACAGCTTCGAGTTCTTTTCGGCTCCAGGCGGTGGCCCCGGTGCGTTCGATCAGCACCAGCCGCTGGTGGGTGGACCCTTCGGGCGCGATCAGCCGCCCGCCCGGCGCAAGCTGATCCAGCAAGGCCTGCGGAATGGCCAGGCCCGCCGCAGCCACAACAATAGCATCGAACGGCGCCACGCCGGGCACGCCCAGCATGCCGTCGCCATGGATCAGGCGCACCCGGGTGGCCAGGCGCAGCGCCCGCAGATGGCCGCGCGCCAGCTCGTACAGGCCGCGGATGCGCTCGATGGCATGCACCTCGCGCACGATCTGGGCCAGTACCGCCGCCTGGTAGCCGCAGCCGGCGCCAACCTCGAGCACCCGGGCCGGGGCACGGTCCTCGCAGACGGCGGCGATCATGCGGGCCACCACCCACGGCTGCGAAATGGTCTGCGAGTGCCCGATGGGCAGCGCCGCGTCTTCGTAGGCACGGCTGGCCAGCGCTTCATCGACGAACAGATGGCGCGGCACCGCCGCCATGGCGTTGAGCACCCGTTCGTCGACGATGCCCTGCGTGCGCAGCCGCTGCACCATCGCCTGGCGCAGCCGGTCGGAGTTCAGGCCCAGGTTGCCGCTGGCCAGCGGCGCGGGCTGCGCAGGCGCGCGCGGCAAGGCGCCGGCCGAAATGCGGGTGTTGCTGTTGGCCGGCGTGATGCCGGGCGCGAGGCGGCCGCCGGCCGGCGGGTCTACGCGTTTACGCATAGCGGCTCCGCCCAGTTGCGCACATCGTCAAGCTGGCTGTGCTGGGTCAGGTCCAGGCGCAGCGGCGTCACCGAGACCTGCCCCTGCGCCGTGGCGTGGAAGTCCGTCCCCGGCGTGGCGTCGGCGGCCAGGCCGACCGGGCCGATCCAGTACACCGTGTCGCCATAAGGCGTGGTGGTACGCACCACCGGCTCGGACGGATGGCGCTTGCCCAACCGCGTGACGGCGTAGCCTTTCATGTCTTCGTAGCGGCGATTGGGGATATTGACGTTGAGCAGGACCGGCGCGGCCAGCGGCTGCGCGATCTGGCGCTCGACCACCTGGCGGGCGGCGCGCGCGGCCGATTCGATGTGCTGCCAGCCTTTTTCGATCAGCGAGAAGGCGATCGAGGGAATGCCGAACAGGTAGCCCTCGCTGGCCGCGGCCACCGTGCCGGAATAAAGCGTGTCGTCGCCCATGTTGGCGCCATTGTTGATGCCGGACACCACCAGGTCGGGGCGCGCATCCATCAGGCCGGTCAGGGCGACGTGCACGCAATCGGACGGCGTGCCGTTGACGTAGATGAAGCCGTTGGAAGCGGTGCGCACCGTCAGCGGCCGGTTCAGGGTCAGGGAATTCGAGGCGCCGCTGTGATTCGTCTCCGGCGCGACCACGGTCAGTTCGCCCAGCCCGGACAGCGCCTCGACCAGCGCTTCCAGCCCGGGGGCGTTGTAACCATCGTCGTTTGAAACCAGAATACGCATCAATCTTCCTGAATCGTGGGGATCGCCACAAACCGCGACCGATTGTACCGTCATGAAGCGGCATCATCGCGTCAGAATCGCCGCCCGAGGTAGAATCCGCAGCCAAACGACGCAACCGTAACGGAATGCCTGCCACCATGGTCCTGACCGCCCCTTCGCTCCTGTCCAGTTCGGCACTGATTGTCCTGGCCTATCTGATCGGCTCCATCCCCTTTGCCGTCGTGGTCAGCAAGCTGATGGGGCTGCAGGATCCGCGCAGTTACGGCTCCGGCAATCCGGGCGCCACCAATGTGCTGCGCACCGGCAACAAGACCGCCGCCGCGCTGACCCTGCTGGGCGACGCGGCCAAGGGCTGGTTCGCGCTGTGGCTGGCCCGCGCGCTGGTCCCCGAACTCTCCTGGGGCGCCTACGCGCTGGTGGCGCTGGCGGTGTTCCTCGGCCACCTCTACCCCCTGTTCCTGCGCTTCAAGGGCGGCAAGGGCGTCGCCACGGCGCTGGGCGTACTGATGGCCATCGAGCCATGGCTGGCCGTGGCCACCATCGCAACCTGGCTGATCGTGGCCGTGTTCTCGCGCTATTCGTCCCTGGCGGCCCTGGTCGCCGCATTTTTCGCGCCCGTCTACTACGTATTCGGCTCGGGCGCAGCCTGGCATGCGCGGCTGGAAGTCGGCCTGGCCATCGCCGTCATCAGCGCCCTGCTGTTCTACCGCCACCGCGCCAACATCGCGCGGCTGCTCAAGGGCACCGAAAGCCGCATCGGGAAGAAGAAGTAACCCACTCAGGAGCCTGCCCCCGCGGGGACAGGCCCCCCGTCAGCCTACCCGGCCTGGATATCCGCCAGGTCCCAGCGCGGCCGCACCGTGAAGGCGTGGTCGCCCTCGCGCAGGTCGGCCAGTCCGGCCTTGACCCGCTCGGCCGCCGCGAACGCGATCATGGCGCCATTGTCGGTGCACAGCGACAGCGGCGGAAAATAGGCTTCGGCCCGCAAGGGCTTGAGCGCGCGCGCCAGATGCGCGCGCAGCAGCGCGTTGGCGCCCACCCCGCCGGCCACCACCAGGCGGCGCAGGCCCGTCTGCTTCAAGGCGCGGATCGCCTTGGCCGCCAGCACCTCGACGATGGCGGCCTGCGTTGCCGCCGCCAGGTCGGCGCGGTCCTGTTCGCCCAGTTCGCCGCCATCGCGCGTGGCCGCTTTCACACGGGTCAGGACCGCGGTCTTCAATCCGCTGAAGCTGAAATCCAGGTCGCCGCTGTGCAGCATGGGGCGCGGCAGGTCGTAGCGGCTGGCGTCGCCCTGCTCGGCCAGGCGCGCCAGCGCGGGGCCGCCCGGATAGCCCAGGCCCATCAGTTTGGCCGATTTGTCGAAGGCCTCGCCGGCGGCGTCGTCCAGCGTCTCGCCCAGCAGTTCGTAGCGGCCCACGCCGTCGACCCGCATCAGCTGGGTATGCCCGCCCGAGACCAGCAAGGCCACGAACGGAAACTCGGGACGCGGCTCGGCCAGCAGCGGCGACAGCAGATGTCCTTCCAGGTGATGGATGCCGATGGCCGGCAGCGCGCGCGACCAGGCCAGCGCCTGGGCCACGCTGGCGCCCACCAGCAAGGCGCCGGCCAGGCCCGGCCCGGCGGTGTAGGCCACCGCGCCCACGTCGGCCAGCGTCAGGCCGGCCTCGGCCAGCACCTGGCGGGTCAGGGGCACCACGCGCCGGATATGGTCGCGCGAGGCGAGTTCGGGCACCACGCCACCATATTCCTGGTGCATGGCGATCTGGGTATGCAGGGCGTGCGCAAGCAGGCCGCGCTCGGTGCAGACGGCGGCCACGCCGGTTTCGTCGCACGAGCTTTCAAAGCCGAGAATGATCATGGGCGCAGAGTTTACAACCAGGGTCCGCGGGCCCTGGTGCAAAAATACGGGTTTTGCGCTTACATTATCGCCTGCGCGGCAGGCGGCGCCGGCGCAAGCACACAACAACCGCTCTCAAACCCCCGGGGACTTCCATGCTGGAGAAGCTATTCCAACTGCGTGACCACGCCACGACCGTACGCACGGAGATCGTGGCTGGGCTGACGACATTCCTCACCATGTCGTACATCATCTTCCTGAACCCCGACATCCTGTCGAGCACCGGCATGGATCGCAATGCCGTGTTCGTGGCGACCTGCCTGGCCGCCGCCCTGGGTTCGCTGATCATGGCGCTGGTGGCCAACTGGCCGATCGGCATGGCGCCGGGCATGGGCCTGAACGCGTTCTTCGCGTTCACCGTGGTCAAGACCATGGGCTACACCTGGGAGCAGGCGCTGGGCGCCGTGTTCATCTCGGGCGTCATCTTCCTGTTCCTGACCATCTCGGGCATCCGCGCCTGGCTCATCCGCGGCATCCCGCACTCGCTGCGCAGCGCCATCGCCGCCGGGATCGGGCTGTTCCTGGCCATCATCGCGCTGTCCAACGCCAACATCGTCGTCGCGCACCCCGCCACCAAGGTGACGCTGGGCGACCTGCGCGAGCCCGGCCCGCTGTTCGCCATCCTGGGCTTTTTCATCATCGCGGCGCTGGATGCGCTGCGCGTGCGCGGCGCGATCCTGATCGGCATCCTGTCGGTGACCGTGCTGTCCATGCTGCTGGGCTACAACCAGTTCAACGGCATCTTCTCCTCGCCGCCCAGCCTGGCCCCGACGTTCATGCAACTGGACATCCTGGGCGCCCTGCACACCGGCTTCGTGCACGTGATCCTGGTGTTCGTGCTGGTCGAGGTGTTCGACGCCACCGGCACGCTGATGGGCATCGCCAAGCGCGCCGGCCTGGTGCCGGAAGACCGCCCCAACCGCCTGGGACGCGCGCTGTTTGCCGACAGCACCGCCATCGTGGCCGGCTCGATGCTGGGCACCAGCAGCACCACCGCCTATGTGGAAAGCGCCTCGGGCGTACAGGCGGGCGGACGCACCGGCCTGACGGCGCTGGTCGTGGCGCTGCTGTTCCTGGCCGCGCTGTTCATCGCGCCGCTGGCCGGCTCGGTGCCCGCCTACGCCACCGCGCCCGCGCTGCTGTATGTCGCCGGGCTGATGATGCGCGAGCTGATCGACATCGACTGGAACGACGTGTCCGAGGCCACGCCGGCCGCGCTGACCGCCCTGGTCATGCCGTTCACGTACTCCATCGCCAACGGCCTGGCCTTCGGCTTCATCAGCTACGTGGTGCTCAAGACCTGCACCGGCCGCATCCGCGAGGTGCACCCGGCCACCTGGCTGGTGGCGATCCTGTTCATCGTCCGCTACGCCTTCTTCCCCGAATAAGGCCGGGCCGCGCGCCTCGCCCCGCAAGCAGGCCGCCTCGCGCGGCCTGCCTGCTTTCGAGGCCTTCAATCGCCGCGATACAGCGAGACTATCGACCCGATGGCGCCCAAGGTTGTTCGGGTGCGCGGTTGAAATCGCCGATACACTCTCCATATATTCCTGACCCGTCGGGCGCGCCGCGCCGCGACACAACCGGAGCACCCGCATGAGTGTATTGGCCAGCGTGCCGTTCTCGGTCCTCGACCTTGCCCCCATCGTGCAGGGCGGCACGGCCGCGCAGGCGTTTCGCAACACCGTCGACCTGGCGCGCCACGTCGAAGGCTGGGGCTATCGCCGCTTCTGGCTGGCCGAACACCACAACATCACCGGCGTGGCCAGCAGCGCCACGGCGGTACTGATCGGCCACGTCGCCGCGCATACCAGCACGCTGCGGGTGGGCTCGGGCGGCGTGATGCTGCCCAACCACGCGCCGCTCATCATCGCCGAGCAGTTCGGCACCCTGGAGAGCCTGTTTCCCGGCCGCATCGACCTGGGCCTGGGCCGCGCGCCCGGCAGCGACGGGGCCACCCAGCAGGCGCTGCGGCGCGGGCCGCGCAGCGGCCTGGACTTTCCCGAACTGCTGCACGAGCTGCGCGCGTACCTCGCGCCGGCGCGGCCGGGCCAGCCGGTGCGCGCGATTCCCGGCGCCGGCACCGACGTGCCCATCTGGCTGCTGGGCTCGAGCGATTTCAGCGCGCGGCTGGCCGCCGAGCTGGGCCTGCCCTTCTCGTTCGCGGGCCACTTCTCGCCCGAAGGCATGGCCGCCATGCGCCTGTATCGGCAACTGTTCAAGCCGTCGCAGACGCTGGCGCGCCCCCATGCCATGATAGGCGTGCCGGTGGTGGCGGCCGACACCGACGAGCAGGCGCATTTCCTGTCCACCACCCAGCAACTGAAATTCCTGTCGCTGATCCGCGGCAACCGCCTGCCGCTGCAGCCGCCCGTGGAAAGCATGGACGGCATATGGAACGAGTGGGAGCGCTCCGCGGTCCAACAGAGACTGGGCGCGGCCATCGTTGGCGGCCCCGATACGGTCAAGCGCGAACTGGAGAGCCTGGTCGCGCAGACCCAGGCCGACGAGGTGATGATCGTTTCCGATTTTTACGACTTTTCCGATCGGCTGCGTTCGTACGAGATCGTCGCCTCGCTCAAGCAGGACGCAGGCGTATCAACCCGCACCGCGAACGCCTGACCGGCACGGCGCGCGATCGCGCCACGCGTTTCGCCCACCGACCACGGACGGAACATCCACTGCGCGGCCCCGGCCGCGCCAACCGGGCCCACGGGCCCCAGACGCCACCCTACGCGGGCGGCAAGGACGACACGCATGAGCATCGTTGAACTGACCAAGGACACCTTCCAGGACGCCATCACGCCCGACGGCACCCTGATCATCGACTTCTGGGCCCCCTGGTGTGGCCCGTGCCGCGGCTTCGCCCCCGTGTTCGAGCAGGCGGCCGAGCAACACCCCGACGTGACCTTCGCCAAGGTCAATACCGACGTCGAACAGGAGCTGGCCGGCGCGCTGGGCATCCGCTCGATCCCGACCTTGATGGTGTTTCGCGAGAAGGTCCTGCTGTTCTCGCAACCCGGCGCCCTGTCGGCCGGCCAGCTCGGCGAGCTGCTGACCAAGGTCAAGGAAGTCGACATGGCCGAGGTGCACCGCGATATCGCGCAGGCGCGCGAAAACGGCGAAGGCGAACAGGCCTGAGGCCACGGCGGGCCTGGCTCAGGCCTGCACGTCCCAGCCGCCGCGCCCGCGGGTGATGTTGGCGAACGTGCGCGCCAGCTCTTCGAGCGCGGCGCAGGGCACGTCCAGCTCCAGTTGCGCGCCGTCGGCGTCGAAGGTTTCGCTGCGCACGCTGGCGCCCGCCTGCGCCAGCCGCGCCTGCAGCAGCGGCAGCTCGGCGAAGCCGCAGCGGCAGCGCACCGTCGCCAGCGCGATGACCGGCAAGCGCTCGCCGGCGCGCAGGCAGTTGGCGGCGCAGCCGCCATAGGCGCGCACCAGGCCGCCTGCGCCCAGCTTGATGCCGCCGAACCAGCGCGCCACCAGCACCGCCACGCGGTCCAGCCCCTGCCCGTCTATGGCCTGCAGGATGGGCCGCCCGGCCGTGCCGCCCGGCTCGCCGTCGTCATTGAAGCGGTATTCGTTGCCGATGCGGTAGGCCCAGCAATTATGCGTGGCCGCCGGGTCGCTGTGCGCAGCGAAATGCGCCATGGCCTCGGCGATCGTGCCCACGGGCGCGGCATAGGCGGCAAAGCGGCTTTTCTTGATTTCTTCCTGGTGGCGGCAGGCGGCGGCAAGCGTGTGCATCAT

Protein sequences of DBSCAN-SWA_1

>NZ_AP014582|3111194:3119260|3111194_3112079_-|WP_003811022.1|DBSCAN-SWA
MLNGQLQLTESQSVAGASAAAASRPVLWAGVLAIALLAGCASKGPRAPVVDLTGQPGASGPTDGSYVVKPGDTLYKIARANNVDIENLKRWNNLTDPNQISVGQVLRLSSSGAGGAQTTPVTSSKPQPKPLDQGSAETPAGGMEAGAGGETGGATTPPAATVPDPKPARAADAAVINWGWPANGAILQTFNSNTKGIDLAGSLGDPVIAAADGKVMYSGNGVRGLGNLIIINHQNGFITAYAHNRALLVKTGQNVKRGAKIAEIGETDTTSPRLHFEIRRQGTPVDPMQYLPPR
>NZ_AP014582|3111194:3119260|3112860_3113619_-|WP_003811017.1|DBSCAN-SWA
MRILVSNDDGYNAPGLEALVEALSGLGELTVVAPETNHSGASNSLTLNRPLTVRTASNGFIYVNGTPSDCVHVALTGLMDARPDLVVSGINNGANMGDDTLYSGTVAAASEGYLFGIPSIAFSLIEKGWQHIESAARAARQVVERQIAQPLAAPVLLNVNIPNRRYEDMKGYAVTRLGKRHPSEPVVRTTTPYGDTVYWIGPVGLAADATPGTDFHATAQGQVSVTPLRLDLTQHSQLDDVRNWAEPLCVNA
>NZ_AP014582|3111194:3119260|3118270_3118654_+|WP_003811007.1|DBSCAN-SWA
MSIVELTKDTFQDAITPDGTLIIDFWAPWCGPCRGFAPVFEQAAEQHPDVTFAKVNTDVEQELAGALGIRSIPTLMVFREKVLLFSQPGALSAGQLGELLTKVKEVDMAEVHRDIAQARENGEGEQA
>NZ_AP014582|3111194:3119260|3117109_3118135_+|WP_003811009.1|DBSCAN-SWA
MSVLASVPFSVLDLAPIVQGGTAAQAFRNTVDLARHVEGWGYRRFWLAEHHNITGVASSATAVLIGHVAAHTSTLRVGSGGVMLPNHAPLIIAEQFGTLESLFPGRIDLGLGRAPGSDGATQQALRRGPRSGLDFPELLHELRAYLAPARPGQPVRAIPGAGTDVPIWLLGSSDFSARLAAELGLPFSFAGHFSPEGMAAMRLYRQLFKPSQTLARPHAMIGVPVVAADTDEQAHFLSTTQQLKFLSLIRGNRLPLQPPVESMDGIWNEWERSAVQQRLGAAIVGGPDTVKRELESLVAQTQADEVMIVSDFYDFSDRLRSYEIVASLKQDAGVSTRTANA
>NZ_AP014582|3111194:3119260|3114436_3115477_-|WP_003811013.1|tRNA|DBSCAN-SWA
MIILGFESSCDETGVAAVCTERGLLAHALHTQIAMHQEYGGVVPELASRDHIRRVVPLTRQVLAEAGLTLADVGAVAYTAGPGLAGALLVGASVAQALAWSRALPAIGIHHLEGHLLSPLLAEPRPEFPFVALLVSGGHTQLMRVDGVGRYELLGETLDDAAGEAFDKSAKLMGLGYPGGPALARLAEQGDASRYDLPRPMLHSGDLDFSFSGLKTAVLTRVKAATRDGGELGEQDRADLAAATQAAIVEVLAAKAIRALKQTGLRRLVVAGGVGANALLRAHLARALKPLRAEAYFPPLSLCTDNGAMIAFAAAERVKAGLADLREGDHAFTVRPRWDLADIQAG
>NZ_AP014582|3111194:3119260|3115611_3116904_+|WP_003811011.1|DBSCAN-SWA
MLEKLFQLRDHATTVRTEIVAGLTTFLTMSYIIFLNPDILSSTGMDRNAVFVATCLAAALGSLIMALVANWPIGMAPGMGLNAFFAFTVVKTMGYTWEQALGAVFISGVIFLFLTISGIRAWLIRGIPHSLRSAIAAGIGLFLAIIALSNANIVVAHPATKVTLGDLREPGPLFAILGFFIIAALDALRVRGAILIGILSVTVLSMLLGYNQFNGIFSSPPSLAPTFMQLDILGALHTGFVHVILVFVLVEVFDATGTLMGIAKRAGLVPEDRPNRLGRALFADSTAIVAGSMLGTSSTTAYVESASGVQAGGRTGLTALVVALLFLAALFIAPLAGSVPAYATAPALLYVAGLMMRELIDIDWNDVSEATPAALTALVMPFTYSIANGLAFGFISYVVLKTCTGRIREVHPATWLVAILFIVRYAFFPE
>NZ_AP014582|3111194:3119260|3113744_3114392_+|WP_003811015.1|DBSCAN-SWA
MPATMVLTAPSLLSSSALIVLAYLIGSIPFAVVVSKLMGLQDPRSYGSGNPGATNVLRTGNKTAAALTLLGDAAKGWFALWLARALVPELSWGAYALVALAVFLGHLYPLFLRFKGGKGVATALGVLMAIEPWLAVATIATWLIVAVFSRYSSLAALVAAFFAPVYYVFGSGAAWHARLEVGLAIAVISALLFYRHRANIARLLKGTESRIGKKK
>NZ_AP014582|3111194:3119260|3112096_3112876_-|WP_010928874.1|DBSCAN-SWA
MRKRVDPPAGGRLAPGITPANSNTRISAGALPRAPAQPAPLASGNLGLNSDRLRQAMVQRLRTQGIVDERVLNAMAAVPRHLFVDEALASRAYEDAALPIGHSQTISQPWVVARMIAAVCEDRAPARVLEVGAGCGYQAAVLAQIVREVHAIERIRGLYELARGHLRALRLATRVRLIHGDGMLGVPGVAPFDAIVVAAAGLAIPQALLDQLAPGGRLIAPEGSTHQRLVLIERTGATAWSRKELEAVRFVPLRAGIQS
>NZ_AP014582|3111194:3119260|3118672_3119260_-|WP_033449764.1|DBSCAN-SWA
MMHTLAAACRHQEEIKKSRFAAYAAPVGTIAEAMAHFAAHSDPAATHNCWAYRIGNEYRFNDDGEPGGTAGRPILQAIDGQGLDRVAVLVARWFGGIKLGAGGLVRAYGGCAANCLRAGERLPVIALATVRCRCGFAELPLLQARLAQAGASVRSETFDADGAQLELDVPCAALEELARTFANITRGRGGWDVQA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003811022.1|3111194_3112079_-	peptidoglycan DD-metalloendopeptidase family protein	A0A292GJG6	Xanthomonas_phage	4.6e-15	49.5
WP_010928874.1|3112096_3112876_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	4.8e-32	46.9
WP_003811017.1|3112860_3113619_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	6.2e-69	51.2
WP_003811015.1|3113744_3114392_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003811013.1|3114436_3115477_-|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	9.3e-92	51.6
WP_003811011.1|3115611_3116904_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	1.7e-66	36.0
WP_003811009.1|3117109_3118135_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_003811007.1|3118270_3118654_+	thioredoxin family protein	V9SJ74	Achromobacter_phage	8.1e-09	25.8
WP_033449764.1|3118672_3119260_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	2.8e-16	46.8

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_AP014582|3616141:3638511|DBSCAN-SWA
ATCACCGCTGGATCGCCAGCACTGCTACGCGGCCGCCTATGTAGTACGTACCATCGACCGGATGTCTGGCTTTGATCGACCAAGAGATCGTTTTCCCTCCCGGCAAGGCATCGCTGATCCAGGTAATCATGGCAGCCCCATCGGGAGGATTCGACAAAGCATTCGGGATGATCTCTCCGTCAATGGAAACAATGGTGTTACGCCCAAATGGAAACCGCCCTCCCGATTGCGCGTACTGCATAAAGACTACTACCGAACCGCCATAGGGCAGGTACAAACTACCGGTCGCAACAGTCGCCAACTCCGATCCCCCTCGCCCCAAGGACTTGGAGATGATGCTGTGAGAGCCTGTCACAACAGCACCAGATGCGAGGCGCAACGTATCGACCTGCGCGACACCTATATGGGCAGTCTTGACGTAGGCCGTGGTGAAGCTGGCCAGCTTCGCTATCAGAGACTCGGCGTTGATCCGATCGGCGCTCATAACGCCTACCACGATCTTTCCCGCGTCTAGGCTCTCGATCTGCGCACTCTTGATCCAGGCCGTCCCGATGAATGCCTTATTTAGGAAGGTTTGCCCATTCTGGACCACGAATGGCGTGGAAATCTTTCCGTTCGCTAGATTGAGGAAGGCGAAGCGATCCGCAAGAAAGTAGACCGATGTTTGCACCCGGCCGCGCTCATTCGTGTAGGCGCCGAGCGCCATGCCAGCCGCGTATACCTTGCCGTCTTGGGCGACCTGCGTCTGGACAGACCAGGTCGCCCGCAGACGTCCATCTAGGCTGGAAAGTGCCGTGCTAGTCTGCTTTACAGCCGTTGCACTCGCACCATTTGCTGCAATCGCATCTTCGACCCGACGAGCCAATGCGCCATCCTGGTTAAGGCGCTCCTCTCTTTCCTGATCCAGCTTCGCAGTGACCGTATTGATGTTGCGCCCCATCCCCGAAATGGTCTGCGTCAAATCACGTGTCAGCTGCTCCGGCCCGATCTGGCCACTCAAGTAGTCAAGAATCTTGCCCGCATCGCTACTTGCACTACCCGGCACGCCCTGCCCGTCGGGATACCATGGACCCACCTGTCCCGCCTCGTCGCGTATTCGCCCCCAGAACCAAATTCTCGTACCATGGCTCAGGCCGAATCGGGTAAAGCGGCTTTGAGGCAACCGAAACTCTCCCATCAACGAAGCATCCCCGAGGTTGGAAGTCGAAGACTCCCAAATCTCGACTGAGCTTATCCATGGGGCGTCCGGCACAGTCCACGCCAATTCAATCGCCATCACTTGGCTTACCGCCGTCAACGCGGAGAGCCTAGGCGGTGGTGCAGCGCTTGCGCTAACGTTGCCCTGCCAAGTCTTCCACGGCCCGGACAATGCGCCGACACCTCGAACCCGCACCTGCCAGGATCCCGCGCGAAGGTGGACCTCAAGACTCGGTAACTCGGCCATCCCCAGAGGCTGCCAATGTACGCCTCCATCGTCACTGGCTTCAAACTCGTAGCGATAGGCACCGGAGGCCGGCGTGGCTGATACGATCTGTTGTCCTGGTCGAGGAGCGGAAAACACCGTCACGCCATCAACAATCGGCCCCAGCGGTACGATGGGTAGCAAAGAAGGAGACGCGAACTCCGGTTCCTGCCCACCCAGTTCCGCTGTATGCACCGATGGTGCATAGTTCACCAAGTCCAGCGTCCATAATCCACCCTCGCTCGGCACCGCCCGCATTACCTGTGCAAGCAATGCCCGCCGCTCGCCTGGACCAAACGTGTAGTGGGTAGGCTCTTCAGTTTCCCCTGTAGAAATATACAAACCGTGCCCATCAACCAAATCCGCAATGCGCATCTCACGCTCGTGCGAGCCCGGCTCGACGCGAAAAGGTCCGGCGGGTCCGCCATCTCGGCCGCGCAAACTGATATAGTGGTTCTGGCCTTGCCACCACTGCAAAGGCTCGGACGTAGTAAGCAGAAGCGCACGAGGATCGTAGTCTTCCACGATTCCCGACAGCCCCCACTTGGGAACATCATGGCTGATCTCGACTAGATCGGCATAGCCCGGAATGGCTCCTTCCAGTTCCGTCTGAAAACTTGCAAAACGACGCTGGTCCCGGTTGCGGGCCAATAGTGCCATGCCCTCACGCCATGCCTGCGCACGCCCCGTCACACCCACTAGACGCAACCGATAAGGCCGCCGTTTGGCCGCACCGGGCCAAGCACACTCCACCTCGTCGTCCTTCCACGTCCTCTCGTTGACGAACTCGACAATGATGTAGTCTGGGTCGTCATGCGCTGGAAACACATAGTCAACGGAGAACGAACGCGTCACGATGTTGGCGGGCGTAAACATCTGCGTTCGCACGGACTTGGGCTCATCTCTGATGACATCTATCACGCCAGCGTGATAGATCGGTAGCGCCCGCCCAGCACGGGCGATCTGCGTCACTGCTTCCCAAAATGTCGTACTGACGTCAAAAACGCCGTCGAACCAATCGCCCCGCTCATCCCAGACTTTTGCCAAGCGATAGAGTGCCGCCAGATTGATGCGGCTGTCCGGCAGTCCTCGTCCATACTCCCGGTCCGTGCACGCATCGGCGATCGCCCAGGCAGGATTACGAGTAGGTTTGAGGTCCTGGGACCACCCTTGGACCGGATCCCAGGTTCGCAACCGCCGGGTGGCGATAATATTGATCCGCCGCGCGGTGGTTTGGTTCAGATTACCCGTCGCGCGCATAGCTACCGCCAGCATCGTGACGTTTCCATAAGTCCGCTGAGATGGCAGGTAGGACCGCAACCCTAACCATGTCACGTCGCGGATCATACGGGTAGCGCGCTCAGCAAGGTGGCCAGAATTTCGCTCTACGCTAATCTCCCAGCGACCAGGCTCTACCTTGTACCGAAATGTCCGGTATTGGGGCGTAAGTGTTGCCGCGACAATGTTCTCCCTACCCAGAACGATCGTAGTACCAATCGGCTTTCCTGAATCATCGATTTGGCGCGCGTACACATTGACGCCGGTGCCAGCCGATTCCAACGTCCCATCATGCGCCGCGTAGAACAACCCCTTTGGCAGGAGGATATCTATAGCGATTTCACTAGCCAGGGTACCCGGCGGGTTTGCTGCGAACGGCCCTTTGGGCCCGGCTCCTTCCACATTGATCGCAGGTAACTCAATACCTTGTACTTCCGCAGAAGTGACGACATTGTCTGGAAACAGCGTCACCTGCCCGCCAGGCTCCACCACCTCATACTCGACCTCCGAAAAATTTCCTATCGGAGTCTCTTCGATTCGTATCTCTTCAATTTCATAGCGCCCTTGTCCAACGCAAAACAACTGGTAGAGATGGGTCTGATTGTTGACCATCTCCGTGTAGGGTTGCGCAGCAAAATCGAGGTACGAACGATACCTGCCGTAGCGAGCAGGTATGGCTTCCATTGGACGCGCCATATTGCCCTGTGCGCTTAACGTATAGGTGGGACTGGCTTTCTCACGCTGCAGCGAGCCTGGCAACCGTGCTGGTGGAAAAAGCGAGTTCACCACCATCCCACCGACCAGACCAACGGCCGTCGCCGCTCCAGCACCAACAGTCAAAGCAGCGGCGCTAGTCGCCGCAACCCCGGCAGCGCCGGCGTACGCAGATGCCGCCCATGCTCCTACACCCGCCGTAGCTGCAGCCAGTGCCGCCATAGCGACCACTTGCAGCGGATTAGAGCCCCCACCCCCAGCCGGCAAGACAACGACCGCCACGACATCATGCTTTCTCAACCGAACGTGCCACGCCGACTGAACCTTCCAGCTTCCATTGAGCTGCACGACAAAGGTCCGTGTGCGCACAAGACTCTTGCCCCGTCCGACGATAAAACCTTCCCGCCGCAACACCGTATCCAGGCGGACACCTTGTGGTGCCACGATGGTTTCTTGCCGCAAATGTGGCCGAAACGGATCGCGCTGTATCGTGATATCAGGCATGGATTCGATAGAAGATAGGCTGAGAAAAACCCATCGTGAACAGCGCGCGCATGGGAGAAAATATGACGCCCCGCCCTTCTAGCGCATGCAGTACGCCACCGCCGTCAAGGTCAAGATAAATGCCGACATGCGGATCATTTCCAGCACGCAACATCACACCATCGCCATGCTGAGGATGAGTCACAATCTTCCAGGCCCCCGTGCGCATCTTGTGCGCATACAGCGCACGTGCTTGCTCACCCAGCGCAGTTTCAGGTATACCGCCTTCAAAGTATCGCTCTCGACATTCCCTCAACAGGCCCCAGCAGTCATAAGCGTCTGGTCCTCGCCCACCCAAACGCCACATCAAGCCGATGTAGCGATTCACATCGCTGCTGGTCATCGGAACAACCCCGGAAAGCGTTCACGCACGTAGCGCTCATGTGGAAACGCCCAGTTATGGACATCAGAAAGCGTCGCTGTTCCAGACACGGAAGAACCCGTCACTGTCACCTTGTTCAATTCCATTGTGATAGGCGGGTTCATTTGAGGCATGCTAAGGTCCGTCGACAAATACGGACGATAGGTAACGTAGATGGGAAACCGTGACTGCACAGCCGCTTCGACATGATCGACGATCTGTTCGCTGGCACCGTCTATGGCAATAAGCAGCGATGGAACCTGACCTTCTTCAAAACCGGGCAATCGGAATCGGAATGCACCTGCCTGAAACATGACGTCTTGCCCGCCGTCAAGCGGCGCCTCAGTTTCCAAGCGGGCACGGATGTCCTCATACCCGAGCACAACGCGAACAGCGGTTGGCTCTCCATGCGGATCTACGAATGCCGGGTGACGCAGTTCCAACGTATCGAACACCACACGATCTTGCGGCGCACTGGCGTAGGCTTCCTTCAAGGCTTGTTCGAGTGACATGACAAAAGCACGGGACAATATGTAAATGCAACGCGAGAGGCTGCAACGCCATTCCGGCATTGCGCATTACGCATCGCTCATCGTTTCCAATTGACCAGAGACACGCCATAGGTCTCCTGGTATCCGTTCTTCACGGGGAACGGGAAGCAACCACCGAACCTTTCTGAGCTTCAGCCCACCTGGGCCGTTGATGGCCATCAGGAACCATCCCGCATAGCCGTTCAGATCGATGGAGCAAAACCGCTGATAGGCATCGTATTGATCACCATCCAGCACGAAGCTCACGGGTGCATGAATCGGATACACGCGGGAATGTCGCCGGTGTCGGGAACGCCCACTATCCATTTCAGTGCGTTGAAAAGGCGAGATAGGCTGGCGCGAGAATTCCACCAACGGCAAGCCCGCTGGCCAAACTGGAAGGGGCATATACGAAACCTATGCGAGTTGACGGCTCAGCCCGTAACGCCGCTCCAGGGCACGAGGCAAACTGCCCATGCCTGAGTCGATGTCATGGGCGAGCTGGTCCTTTACCTGGCGGAAGATTAGATCGAGGGTCAAGCCGCCGCGAGCGTCAGGCCGCGCACGAACCTGTGGCTGGGACTCCACACCGTGCAGGTTCACTGTCACAGGCGTCGAGGGGCGATAGGAACTGTGTGTCAGTGGTGTGACATGTCCACCGTCCCCACCCGCCAACAGATAGGTGCGGCCGCCCTCGTCATACAACTCCGGACCATTCTCAGCCACTTCATAAAGGCGGCGCGGTAGGGTGGGGCCGCCCATCGCGCGTCTACCAGCCAACTCGGGCATGGCCCAACTGGCCGTAGCCGGAAGCGCTGACCCGAATGCGTTCCTGAACACACTGCCAAGAGCGCTTGCCAACGGCCCGGTTATGCTCTGCCGTACGGAAATGCGCGTCAAGTCTGCAATAATGCTATCGGCGAAGTCGGCAAAGCGAGCCTTGCCCGTGACGACCAACTTGACCAATGCATTCTCAGCCCCTGAGAACGCATTGGCGAATGCGCTGCGCGTTAACTTCGCGACATCGCTGACCAGTTCAGCGTAGTCGTTGAACGCCTGCCTCGCCCCTTCCTTCCAGTCCTTTTCTAGAAGCCGCGCCTTGTTATAGTGGTCGGCCAGCAGTTCCAGACGCCGCTCTAGGCTCTGTTTGAGCACACGAACGCGATCCGCATATGCTTGTGGGGTTATTTCTTTCGCCTCGTTCTGCTCTGCTGCGCGCTGCACTTGACGCTGAAAGTCGCGGTAAATCTGCTGCTGAGCGTGTAGTTGCTCGCGCAGGCGTGGACTGGCCGTCAAACCTGCCAACAGGTCGTTGTAGCGCTGTTGGTCAGCAATGAGCGTCTCCTGCGCCGAGCGCTCCAGCACCTTCAGCTGAACCGCTTCCTTTTTTAGGGTGATCTGGTCCGCCAGTCCGGCGTTCAACTCCAGCTGCTGCCGGAGGGCCTGTTCGTTTGCCAGGACGCTCTTCTCGTCCGCGCTGAGCTGGTCCCTTGCCTTCAGATCCGCGATCCGCTGTTCGAACTTGACCAGTTCCTGGCGCGCTGACGTGATCTTGACGGCACTCTCCAGCTGAGCCCGCAGAGCGGCTTCCTGCTCGCGGGCGCGCTCCAGCTCCCGGACACCAGGAGCAACAGCTCCCTTCGACCCGGCGAACTGCCTCTGGATCTGCGCCACTCGAGCGACGTGCAGCTTCAGCGCCTTTTTATACTCGTCGCTGTTTTGCTTGAACTCGGCTGTTGCCTTTTTGAATGCTGCGTTCTCTGCCTCCATGGACGCCGCCAGTGACGCACCCTTGTGCGACTCCAAATAGCTGTCCAGGTCTTTGCGAGCCTGAATACCGCGCGCGACGGCGCCAGCTTGGTCGGCGCGAGACTTGGCCGCGGCCTTTTGCCACTTGTCCAACTCCTCGAGGCCGGCGATCTCGCCACGCAACTGCTTGATCCGGTCGTCATCGAGGAAGGTGCGAAAGCGCGAGGTCTCCAACGACTGGAGATTCTTCCGTGCCTGGGCCAGCTTCTGTTCAAGCGCCTCTTCACGACCGACCGCCAGCATGGCGTCCCAGGCGCCTTTTGCGACGTCGGTCACCGCTTTCCATGCACGTTCCAGATCGCCAATGTTCTCAACGACCTGCGGGTAGCGCTCCTCCATTGCCTGTGCGTAGGTGTTCAGCGCCAGCCGCGCAGCGTCCTGAGTCCGTCCCTCGGCCTCCAGCGCCTTTACCTGGTCATAGACCGCCAGCGTCAGGAAGTGGTAGCGCTCGTTCAGTTTAGTCAGGGCCTCGGCGGGCGCGTCAGCGATCCGCTCATAGTCCTTGACCATTTCGTCGACGCTGCGCCCAGTGGCGGCCTCGGCCAGTACCGCAGCACGGCCCAGCCCCTCAATCGAGTCGCCGGCGATTTTCCCGGTCTCGACCAGCTTCGTTAGGGCTGCAGCAGCGTTTCCGGTGGTGCCCTGAATATCGGAGATCCGATTCGCCATGGCGGCGAGCTGGCTTTCCGTCACGCCGGCCGCGTTGCCAGTCAGCGTGATAGCGGCAGTAAAGCGCCGCCCTTCCTCTGCCCCTTGTTGGTACGCCACTGCTAAGGCGACTGCACCCGCGGCCGCCGCGGTAAACGGCGTGATGAGGCTGGCGACATAGCCACCCACGGCCTTTATCGCCGGCCCAATGCCGCCGAAGAGGTCTTTCAACTGACCGCCTTGCTGCAGGAGAACGTAGAAGGGAGACTGACCCGTGGACAAGCCTACTGCGATATCTGTCATCTGCATCGGCAGTGAACGCATGGCCGTCCGCATTTCGCCCACCGACAGAGTCGCTGCGGCGGTCTGAGCCTGAGCGGCCTTGGCCGCCTTGCCCATGGCTCCAAGTCCTGTAGCTGCCGCCTTTCCCGCCGTACCAACCTTAACCGTCGCCTGCTCAGCTTTCGCGCCGGCCGCCGCCAGCTTGTCAAGATCAGTAGACGCACCTTTGACTTGGGTGCTGTCCACGCGCAGTACGAGAGAAGCGACTTCATCAGCCATAAGGAACCGTTTACACCCAGCCGGGGGTTACTTCTTGTTCATCATCCGCAGGGCTGCGGACTCCATGACGCGCACACCGTCGAACACATCGATCTCTTGTTCCGGCGGGACGCCAAGCATACGCATGACACCTGCGAGCGCGCCGTAATCGAGGCCAGTTGGCCCGGCGAAGCCAATGCGCCACTGTGAGCCCATCGCTTCGAATACCACCTTGGGCATCACGTTGTCCGGCCACAGTTCGATTACCGCGGCGGGGAAATCGTCTGGTCTCAAGCCAAACTCGGCCAATTGGGCCTTATCCGGCATCGGCCGGTACATTTCCTCCGCCGCGGCTATCAGTTTTTTCGGCGAGCCTGCAGCAACTCGAGGCTGTATGCCTGCACTAATGCCGGTACTGCGCCCTGGTAGTTCTGGATCAAAAGCCCGACTGCCTCGTCGCTGAATTCCATGTCGGGGCCGTCCCAGCCGGCGATCATCTCGTTCACCAGTGCGATATCCTGGGACGCATCCGACTTGTCGGCCCGCTCCAGGAAGTCCTTCATCTCGTCCCGTGATTTGTGCCTGAACGTGACCTTGATATTGGCTGGCTCTTCACCATGCCGGGGTATTTCCACCGGTACTGTGAAGGTCGGAGCCGGCTGGAGCTTGAATATGATGTTGCTCATCTCTCCCCCTCATCACGCCAGCGGCGCATAACGTGTGAAATCAGACATCATGGAGAACGTGGCGGTGTTCTGCATATTCACGTCCAGCTCCATCGACGGGTCCGAATCGAAGGACGGGTACACCAGGTAGTACAGTTCGTCGTGGTTGGGCAGCTTCGCCCTCAACACAACCGCATCTTTAGCCGCGTCGGCTTCTTTCAACGCCTCATACCATGCCAAGGCGGGGTCGTAGTCCAGCGTCAGAGTGATGAACTTGGCGCTCTTGTAGGTCGGGCGTTGCCGTTGACGACTGTTGCGGTCTTCGACGTACCTCCATTGATAGAACTGCTGTTCACCTCCTGTCTTGGCCACATTGGTGACCTGTGACAGGTCTACCCATGTCGAAACTGGCGTTGCCGTGCCAATACCCTGCCCCTTGGAAAACCGACCGACCTTCGTCGTATCGATCCCCTCCAATGCGAATGTGTTTGATGCTGTGTTGACCGCACGTACAACACGTTCGTTCAGCTCCGGCCAACCGGACTTCATGATCAGGATCGTGCCTGCCTTCGGCGGACTCGTCGCGCTGGCGACGGCAGGATTGGCATTAGTAATTGCAGAAACAGCAACAGCCGCACCCAATCCAGTAGATACCGAGAAGACGGTGCCGTTGGGGAATATTGCGCTGATGATAGTTCCTTAGGGGGCCAACGGCCCCTCATCGAAGCCCAGAGGGCAATAAAAAACCGCCATGTGGCGGGTTCCAGTTGCGCCCTTACGGGCCATCGGCATACGCCGAATCTTCAGATCGAGCATCCTTCGTGCAGCTTCCGCTTCTTGGCTACATACGCCGCATGAGCTACGGCGGGGTCATCGAACAGCCCGACCTCGTGTGCCTTCCCCGCAACCTGTACGCGACTGCGCCATTTCTTCGCACCTCGCTCCCAATACACCCCTAGGTAGCCTGATTTATTGTCAGCCTGGGGGTGTCGCCGGTTCTGCATATTCACGGCCTGAGGGACATCCCGAAGGTTTGCAATGCGATTGTCTGAGCGGTCGCCATTCATATGGTCTATATGCTGTGTGGGCCATGCTCCGTGCATATATAGCCAGGCAAGCCTATGCGCCAGATACCGCTGTCCGTCGATGCCGACGCGCTGATAACCGTTGGCGGTGGCATGGGCCGCATCGTCGCCCACATTGTGACGCTGGGCGAGGCGGACCAACCGCGTGAACTTGCCCGTTTCGGGGTCGTAATGGACAACTGAACGCAGTCGTTCCGCCGTGATTCTGGCTTCGTTCATTGCTATTTCACTCCGGGTAAAACTGGACGTCATATCCCAGGGATATGGGCACGGTGTGATCGGCGTCTCCCGTGGTGGGCTGTCCGTTACTGATCGGTGTGCGCACGCGCACCGCGAGGCCGCCGGACTGCATGACCAGGTTCACGGGGAACAGCGCGTCAAGCTCCGCCGCAACCTGCTCCGCGCTGCGCGACCCGTCGCCGATCGGCATCACCACGTTCACCTGGAACACGCCGCGGTACTGCCGGTGATCGCCGGCGGCGTCCCGGCTGATGGTCGCGGCGGGCATGACATAGGCGCGCAGGTAGACCCCAGCGGCGGGCGGCGTGAACTTCGTGTTCTGCCACGCCACGGGCAGCGCCGGCGTGCGGGCCTTGGCCCAGTCGCTCAGCCGCTTCTCGAAAGCGGCGCGGATCAGGTCCTGGCTCATTTGTTCGCATCCTTCGCCGCCTGGCTCACGTATTGCTGGAATTCCTGCACCGTCAGCTTGACCATGCCCTGGGGAGCCTGCTTTGACCACCCGTTTTCCAACCGCACCGCATAGGGCAGCGAGTTGGAAAGGTAGGTCACACCGCCAGCGGCGGTCTGCCGGATCTCTGCGACGAGGCGATGCAACGTCACCTGCCCGCCTGGATCGATCGCCATGGTCGTGCCGCGCTGCACGCCCGCCGCCGAGAATTGCCAGTTCGCCCGGAACCGGCCGGTGTCGACGGGCGACTTCAGGATCACGCCCTGGGCCAGCAGCACCGTGGCCTGGCGCGTCGCGGTGTCGACGTTGCCCTTGGCGCGCGCGACGAACTTACCGAGATCAGCGGTGAAGCTCATGCTTGCCTCAACTGCAGTTCGAACAGCAGCACCAGGCCGGCTGGCGCCAACGTCTTGACCGTCACCACGCGCCAGGTGGCGCCCAGCGCCAGCACTAGGTCGGCCGGCTTGGGCTCGGGCATCGCGCCGCCCGCGGCCAGCTCCGGCGCCAGATACATCTGCTTGTCGCCGGTCTCGATGACGGAGCCGGCCATGTTGGCCAGGCCCGCGGCCTGCGCGGTGTAGTCGAACAGCGCGCCAATGCCGTCGTTGTCCACCGTGGTGGTGGACGCCTGACCAAGATCCGGGTCATACTCGCCCGTCACTATCTGGCGCACAGTCACCGGGCCGCCGAACTCATCCAGCAATTCTTGGGCGGTAGCGGCCATATCGGCATAGTCGAAGGTGGCCATCAGTCGGGCTTCCCTGAAACATTCACGTCCATGATCAGCGTGGCGCGCCAGATCGGCTCATCGGTACCCGCTTCCAGCTTCACCGCCACCAAGCCTGGAATCGGTGCGCCGTCCGCCGTGTACAGCCGGATGCCGCGGCAGTCCTGCAAGCCTGGCGCATCGGTGGGCGTCGGTAGAACCAGGCGAAGGAAGTTGCCCATCTCAGCACCTCACCAGCTTGACCGACGAGCCGTAGGACGACAGCCAGCGGCGCAGCATGGCCGTCACGCCCGCATAGCGCGTCTGGCCGTCGTTGCGCGCGCCGGCGGCGTTGGCGTACTTCGTCGTGATCGGGCCGACGGTCTTCTCGATAGCGGCGCCCACCGTGGTGCCGCTGACGTCCTGCCACAGCGGGCTCTTCAGCGCACGCGCCGCCAGTTCGCAGCAGGCGTTCACGACCTCGCGCGGCACGCCGGTGGCGACCGTGCGCGGCCATTCCAGCGCCTGGATGTCGGTGGCGCGCTCGCCGCGGTAGGTGTATTCGCCATCCAGGTACAGCGTGGCGTTGCGCAGCGCGGCTTCCAGTGCCGCAGCCTCGCCGGCGAAGGCCAGGCCATGGTCGGCTGCATAGGCCTGGCAGTCCGCCACGCTCACGTAGCTGTCCGCGTTCGCCAGGCCGGATCCGTCTTCGACGATCAGGGGCATTGAGGTATCTCCACAGGCTGACGGAAGCCCCCGCGTGAGCAGGGGCGACCGTCAAACGGCGGTCAGGCCTTGGCCGGATCCTTGATCCGGGTCCTTGGGCGTCGGCTCGAGTTCCTTCTCCTTGGCGGCCTCGGCCTTGCCCTTCGGCCGGTACTCCGGCTTCAGGGTGACCTTCGGCACGTCCTTGGCGGCCCCCTTGCGGTCCTCGGTGGCGTTGGCATCGACGATGCGCACGCCTGCCTTGGCGGCCTCGGCCTTGACGTCCTGCTCGTAGCGGTAGAACGGGCCCGGCAGGTACCAGATGGGCAGCTTTGCTTTCATGGTGTCCCCTTACTTGGAAGCGTCACCGATGGCGATAACGCCGGCGGTGTGCTTGATATCGGTAGCCACTTTGTCCCAGTTGGTGCCCGTGGCCAACTCGGCGTCGGTCGGCGACTTGCCGCCGGTGGCCTCGTCCCACGTGTAGCCCTTGAGGCCCAGACCAAATGTGTAGTCCGCCTGGAAGGTGGTTTCGATGCGCTCCTTGCCGTTCGAGGTTTCGATGTTGGTGATCAGATCGCCGCCATCAGACACTGTTGCAGCGCCGGCCACCAGACCCAGCACCTTCTGCAGGTTGGGCGTGCCCGTGGCATAGAGCGCCGGCGCGTCAGTTACCACCACAGTCTTGCCCAGGATGTCCACAACAGTGACCGCACCGTACTCGAACAGTTGCTGAGCGTTGACAAGATTCTGGCCGATCAACTTGTGGTAGACCTGGCCGCTCATCACGTTGGCGACGATCAGACCGGAGCTATCGCCGAACTTGGCATGAGCGTCGTTCAGCACCGAGTAGTTCAGTCCGGTCTTGGCCGAAACGTTGACCGTTGCCAAAGCCTGATTACTGATGGCGGCCACTAGCGCGGCAATGGCGGTATTCAGCTGGTCCTGCAAGAGCGCCTCGGCGAAGTGGCGCGAAGCCACCTCGATGCCCTCCGCCGTAGGCTTCTCCAGCCATGTCATTTGCGACGGCTCGTAGCGGATCGGGCCGAAGCCGCCCGCGACCTTCACCGAGCTGTGCTTCAGCTGGGTCAGATCGGTGGGCGAGGCGCTGCCATTGGCAGCATAGCGATCGACACGACGACGGGCGCCGTGGATGGCTTGGTAGAACGATTCCTGGAGGAAGTCGCCTTCGAAGCCGGCCGTGGTCAGCATGATCGCGCCGCGCGAGGCAGCATTGAACTTCTGGATCTGCTGCCCCAGCGTCTCGATGATCGCGGGCATGAAGTACTTGTTAAAAACCTGCATCTGCGAGATAGACATGAATTCTCCTCTATCGTTGTGCGGTATCAGCCCGAAAGCTCGGGGAATTTGGCCTTCAGGGCTGCCACGCGATCCTCGCGCGAGCCGCCCATGTTGCCCGTGCACTTACCGCCACCGTTTCCGCCCTGGCCGCCACCGCCGGTATTCGCGGGTGCAGTAATGAAGTGCTTGCCCTGATCGGTGCTCGCCCATTCCATGACGTGGTCGTCCAGTAGCTTGTCACCGATTACCGCTGCACCGTCCTTGATAGACGTTTGGCTGCGCAGCATTGCTTTGACGGCGTCCATGAAGTGCGGCGCCACGCCGGCCTTGGCCAGCGCGGTCGACAAGCCGCCATCGATCAGGTGCTGGGTCAAGGCGCCCTCCTTTTCGGTCAGGTCCTTGGTCAGCTTTTCGATCTGGCGGGCGCTGTCCTTGGTCGCCTTCTCCAGCTTGCCGGTCAGCTCCTCGACTTGGGTCTGGAGCCGGGCGTGCTCTTCGGGGTCGATCTCGGAGCCCTTGGCTTTCGCCTTCGCCGTGCGCAGCTCGGCGATCAGCTCCTTGTTCTTGGCGCTCAGCGCCTCGGTAGCCTCGGCAGTCACCTCTTCGATCAAGGCTTTGACTTCGGGGTCGTTACGGTCAAGCGGCATGGTGTTGTCCTCTGGACGGTTGCAGGGCACAGCCCCAAATACAAAAGCCCCGCCGACACAGTCGGCAGGGCTAAGAAAGAAAAAAGGCCCGCGCAGTGGCGGGCCGGACGGGAATGGCTCAGATCATTTCAAAACGACGCGCTCACCGCGCACGAAACACAGCGCGCACAGCAGTACCTTCGTTCCGCCCGACCACGAGCGGCCAGACTCGAACACGCCAATGCGGGTCTCAATGACCTCGCGTGCACCACAGCGGTGACACTGGATCATGTCTTTCGGCTTCGGCAGGGCCTTGATCCGCTTCCGGATACGGTCCTTCTCCGTTTCCGCCGGCTTGGGAGCGTCGGGTACGAGGTGGAGAGGCATGCACACTATTTTACGCCGGCCCGGGCAAACGCGGCAGCATCCTTACGCCTCAGCTCGGCCAGCGTGAGATATACGCCTCGGTCGTTGTAGAAACTTTCCAGCTCAACCCCCCCCTTGCGGAACAGCGCGCCGCGGGTCGGACCCAGGATATCGTCCTGGATCGCGGCGGGCTGCCTGCGGAGCCACTCCGCATAGGTCGTTGTCGCCCGCACTTGCTCGCCCTTGCCGCGCGCGCTGTCTCGGTAGTCCTTCGCCGCTCTGGTGCCGATGAGCGGGTCATCTTCCATCCCCTTCAGGATCGGCACTGAGCCGCTGCGGCAACACCAATGTAGCTTGCCAGGGCCAGCGCCCCAAGGGACTCGGTGGCCGATCGGTTTGTGATCAGTCGTGTACTGCAGGCCATCGCGCAGCCGGCACATCTGGCTGGTGCGCGAGTCCAGCGTACTGACCCAGACCAGCGCGCCGATGATGTCGTCGTTGGCCTCGTACCAGCGATCTCGGGCAAGGCCGGCCGTGTGGCTGATTGCAGTGCGCACCACGGCTTCGGCGTTGCGTCGGTCGATCTCCAGCAGACCGTCAGCATAGCCCTTCGCCCGAGTGCCGCGCACGCGCTGCACCACCTGCTGAATGGTCTGTCCCTCCACATAGCCCATGCGCACGGCATCGCGGATTCGGCTGGCGCGCCCTGACTCGAGACCGGCCATCCATTCCCGCAACAGGCGCCCCTGGAATGGTTGAGCCATAGCGCCGACATAGACCTGCCCGGCCGTGACACCGCGCGTGGTGAACTCGATGCCCAGCGATTCGAATAGCTGGCTCTGGTAGCCGACCTCGTAGCCAGCTAGGTCACGCAGATCCTTCTCCAACTCGCCGCGCACCTGCCGGTACGCCTCGGCGTTCAGGTTACGGACGTCCTTCAGCACCGCATCCAAGCGCGCCACCGTAAAGGCGCTGGCTGGCAGACGTTCCATGGCCCGGGCCACCTGCTCGGCCAGGTCGATGTCGACGCGGTTTAGCAAGGCAATAATCCGACGCACCACCCCGTTGCTGTAACGCACCAGGTCGATGGAGTGCCGGACGGTGGCGTCATACAGCTCTGTTTGCAGGCTGGCCATCCTGGCCTCCCAGCGTGCCCAGCGCCGGGCCGGCAGCTTCGATGCGGGCTTGCTCTTCCTCGAATGTCACCCCGTCGTCGATGATGCCGCCGCGGCGCATGTTGTCGTAGAACGTTTCCGGGCTGATCGCCGCGGCCTGCAGCGCGCCCACCAGGGCGGTCAGGTCCTGGGCGGTCAGGCCGACCGGGAAGAACTCAGTGTTCAGCTTCACCTCGACGGTGCCCGAGCCGGCGCCTGCCCACTCGGCGGCCCAGCGGAAGGCCTTGGCCAGCGACCGACCCACGCCCAGGGCGATGCCGCCCAGCACGCTGTTCTCGCCGGCTCGGTGGATCTTGGCCGTCTCGGCCGCCTCGGCGTCGCGCTTCTCCGGTGCCAAAATGCGGGCGCCCAGGGTGGCCATCATGCCCTCCTTGCGCTCCAGGCTGACCTTGATGCTGTCCAGGCCCTGGCCGGAGAACTCCAGGTACTGAGCTCGCGCCTCGGCCTCGGAGAATACCCAAGCCTCGGAAGAGCCGATCTTCAGGGACTGGCCAGCCTGCAACTCATGCCCGGTAACAACCGCCGTGGGCAGCGCCGTGAAGTGCAGCGCGTGCTCGTAGTCGGCCGTGCCACGGTAGTGCGACATGTTCACATCGACCAGGTCGAGTAGCACAGGCTTCTGTGGGTCGATCGCTTCACCGTTGCGCCCTATCAGGACGAAGGGGATGTAAGGCAGCCGCTTGCCGTTCATCATCGGCGTGTACTCGAATGCCGGCGTGTTCAGGTCGGTGCGGTAGATGCGCACACGATAGGCACCGTCCGCCAGGTCGAGCACCCGGTACTGCGTCTTCTCCTCGGCGGTGAACTCGTCCTTCTGCTCGGTGTAGGTCTCGGCCAACACCACCAGCACCAGCTGGTTCACGCCGCTCACCCGGGCCGTGCGCCAGTTGATGATGGCCTCGGCCTTGTAGGTGGCCAGGTAGGGCCGCAGGCCGACCGCCTGGGCCTGGCCCACGGTCATGAACTCGCCGCTGGCCACCGGGTAATCCACCAGCACGCCCACGCGGGTGACGTCGATCACCTCCTTCACCACGTTCTCGATGAACGTGTCTACCGGCGTGCCCGCTAGGTCGGCGTCCTCGATCATCGGCTGCAGCGCCGCCGGCAGCGTCACGGTGGGCTCCTTGCGGAACACCATGCCGATCAGCGCTTCCTCGGTGCGGGCGGTGGCGCCGTAGAACAGCGCGCGGCCCTTGTAGGCGTCGTACTCCTCCTGCTCCTGCCCTGCCAGCTTGGGCAGGTACTTGGTGCCGGCCGCATGCACGGCGTCCTGGCCCTGCAGCGCGGTTCGGCAGCGCTCCCATCGCGGCTGGCTGGCCGTCCAGAGAGGGTGTTTGCTGTCGACGGGCATGATCAGGTTCCTGTGAGTTTGATGCGGCTCATGCCGGTGGGCGTGATCGGGTATCGGTGCACCAGGAAGTAGCCCTGGGCGTCGTTCGGGTGGTCGTGCCCCGTCGACTTGTCCGGCTCCCCGTTCTTGTCGTAGGCCTGCTGCTCCAGCGCCTCGGTCAGCGTCGGGCACCGGTCGGTATTGACCAGCCAGCGCCGGGCGCCTTCGTCGTTGAGCAGCATGCCGTTCACGGCGTTGATTCGGTCCTTCACGGCCGGGTTTCGGCTGTTCACCCGAACGGTGAACCCCGCCTTGCGCAGGATGCTCAAATCCGACTCACTGGCGTTTTTGCTGCTGGTATTCCCGCCGCTGGCGTCGGGGTAGATCGTGACGCCGTGGCCCTTGTCCTTGAAGCGCTCCTTGAGCATGCGGGCCATTTCCGGCGTGTCGCGCACCTTCGTCAACTCTCCCACCGTCAGCGGCAAGCCGGCCCGGATCACGTTGACCGTCGCCGTCATGTTCAGCACGTTGAAGTCCATGCCGATGTGCAGCTCTTCGTGCGGCTCCTCGGCGGCGTCCGTGTGGTGCAGGCGCCGGTCAAAGTTGGGGTACACGCTACCGCTGGTCAGGTTGGTGAACTGGCCACGCAAATACGCCGCGATCAGCTGCGGCGGATAGCTCGCCCGCAGCGACGGGATGTAGTCTTCCGGCAGGTTCTTACCGTTCTCGTAGGTGCTGGCTTGCACCAAGCCGTACAAGGCAACCAGATCGGGCCGCTCGCGCACCTGCTTGACGAACTGCTGGTAGACGAACTTGAACCCCTCGGGCGTCGTCGTGACGTCCACGCCGTTGATCAGGCCGGGCGCGGTGTGGCGCAGACGAGCAATGATCTTTCGCCAGGCCAGCGCGGCCTTGTCCGTCTTCATGACGTCTAGCTCGTCGATCAGCCCCTTGCCGATCTTGAAGCCCACGATGTCGCCCGGCTTCTCCATCGACCGGCAGATCACCGTGCCGCGGTACTTGCGGCCAGCGAACAGGTGCACCTCCTTGTTCGACTCGTTGATCTTGGCTGCCAGCCCCCAGTCGTGGGCCACCTCCTCGATCGTCGGGTAGAAGATGTCCCGGATCTGTCCGTAGGTCGGCGCGAAGTAGCCAGAGTTGACCCGGGGAAACTCCCAGGCGTGGCGACACAGTCCGGCGCCACCTACCCAGGTCTTGCCGCTGCCGAAGCCGGCGACGAACGCGCGGAACTTGTGCGGCAGCGCCAGGAACCGAGCCTGGGGCTGATTAAGGCTCGGCATCGGGGACGCTCGCGTCCTTGACCTCGATCACGACCTTCACCGGCGGCGGCGCGTTGTCGTCGTTCGTGGAGTCCGGCTTGTCCCGCCAGCTATCCGGCGACCGATTCTTCAGATAGAAGATCATTGCGGTGACGTTTCCGCCCACTGCCGCGTCATACAGCGCAGACGACACATCCGCGATGCCGAGCGCCTTCCCTTTTTTAAGGGCCGCCTGGAGCTGTTCATTGCTCGCCTTGTGGCGGCGTAGAGTGCTGTAGGAAATTCCCAGCGCGGACGCAATCTGCTCTTCGTTCAAGCCCTTAGAGGCCAGCGCCTCTATCTGCCCTAGATCGGGCAGTTCTTTCTTCGGTCGTGCCATAAGCTCGCGGTCCCTCTGGGAGCGACGCCGCAGGCATCGATTCCGCGTTGAAAGTGATTCAGGATGCGCCCATCCGACTTACCCGCCAACGGAGCGAGCTGGGCGTGTGCGGTTCTCGTCTACCAGATCCAGCGACGAGGCCGGGGAGAAAGCCCCGCGCGCTTTGATATCCCGCGCGGGCGCCCGTCTGGCTAGGCGGTGTCCTGGGGCGGTGATTCTTGACAGTCCCGAGCCCGCAAAGCAAAAGCCCCGGCCATCGGCTCGGGGCTTCGTTTCTGACGGACGCACAGCGCCCGCCATGGGCATCGGGTCACGTCCTTAGACGGTAGTCGGTCTGTCTTGGGCTGGATTATGCATAACAACGGCGTAGCGTGCAACAAAATCCTCGAAGTTGCTGACCGCCCGCACCAGCACGTCGTCGTATTCGCGCGATCGAAGGTCCAGCGCGCGACATGTTGCCCGCCAGTACGAGCGCGTCACGTAGTGGGCCCGCAGGATGTCGCGGTGCTGATGCAGCATGCGGTAGACCGAGTTGCGCCAGGCAGCCTCGATGAGACCTGCGTCGCTCTCGTCGAGCTCGCGCATATCTTCCTCGCCTCCCCATGCGCCCTGTCCTGCCCGCTTCGCAAGCCTGCGGCACACCTCGTAGGTAGGCGAGACAGCGTAATGCGGCCGGCTACGCATGACTTCGCCCCAGTTCTCGAGGCGGGCATGGAAGTCTGATGGCAGGCGATCCAGCAGCAGCTTGGGCGTCTTCATCGACCTCGTTCCTCGAAAAGTCGGCACCGCTGGCCTACCTGCATGCCATGACCGCAAGCCAGAATGCGGCGCCCGTCGAATTCGCTCTTGACCAAGCGGATATGCGCGCAGCCAGCGCAACTGCGCAACGGCGGCGGCTCTTGGCGGCGCTCTAGCACCTTGAGCGGGTCGCCGCGCTCGGACCGGCGGGCCCACGTCATGCTGCACGCTCCTGCGCTACCGCCCAGCTCAGAATGGCCAGGGCGTCGGCGTCGTTGTCGGTCTCGGGACGGAATCCGCGGGCCTTCGCCTCAGCGATCATGTCGGCCTTGTCGGCGTTGCCCTTCCCCGTCCAATGCTTCTTGATCGTGCCCACACCCACAGGCAACAGGCGCAGGCGATGGCTGTCGGCGAGCATTTCCACGATGCACAGGAAGGCGCCGTAGGCATGCGCCGCGTCCGTGCCGGTGTGCCGCTTCACATCCTCGTAGGCGATGGCGTGCACCTGGCGCTGGGTGATCACCTCGACCAGGAAGGAACGGGCGCGCAGCCAGCGCTGGCCGGGCGACCAGCTGGCGCGCGGCGTGAACACCTCGGTGCCGTGGGAGGTTCGGCCGTCGCGCCCGCGCACCGCCCAGCCCAGCTTCGTGCCCAGGTCCAGGGCCAGGATGGTGACGTTCGGGCCCAGCTCGGGCACCACCGTAGATCCAGCATTGGCGCGGCGTGGCGCGGCGTCGGGGGCCGTTTCAGCACCACCTCGCGCCCAGGGATCTGCGACGTCCGTGTTAATTTTTTCGAGGTCGAATGTGGGCACGCGCGCGTGGCTGCCCGCCAGCGTCCCCGCCAACGGGTCCAGCGGAACGCCTGCCGGCTGCCCGGCGATCAGGTCAACGTGCGTCATGCGAGGGCTCCAATCATGTCCAGGGGCTGGCGACGCTTGTCGCCGGTGAATTGCAGGCTGTCGGCGTGGCGCCAGAGCTGGATCCGCCCTTCCCATTCGCCGTGCCGATTCTTGTCGCAGATCAGCAACGTGTCAGGGGAGTCGTGCGTGTCGGCGGAGACTTCTCCGTCCTTGCGCAGCTCGGCCTCGGCGATCCGCTCCTTTTTCTTGTTCCGCCAGACGGTCAGCATCTGGTCGACCTGGTCGACGATGGCCCCCGAGCCCTTGGCCGAGAACTTCCCCGGCACCTGGTCCTCGTTCTCGCCCTTCTTAGCGTGGTGGACCAGGTGGATGTGCATCCGCAGGTCGCGCGCCAGCGTGCAGAGCATGTCCACGAAGTCCTTCTGGCCGTTGTAGTCATCCTCGCCCCGCACGCACTTCATCAGGCTGTCGATCACCATGTGACGGACCTTCAGGCGGTCAGCGCAGTACCGAATCACGGCGTACAGCATGGCCGGCGTCACGGTGCCCTGCTGGTCGTACAGCCACAGCCGGTCCCGCGACCAGTCGATGAGGCGGTCGACGGCCTGCACGCCAGGCCGGGCGTTCATCGCCGTTTGACGCAGCATGCGCTTCAGGGTGGCCTGGGGCTTCATTTCGAACGAGGCGATGCACACCCGCTCGCCCTGGGTAGCAAAGCCGATGCAGGCCTGGCCCAGCAGCTCGCTCTTGCCGTGGCCGTTGATGCCCTGCCACAACGTCACCTCGCCCGGCCGGAAGCGCAGCAAGTCGTGCGTCTTGGACCAGGGCAGCTTGGCGCCCGTGATCTGATCCCCGTGCTCAACGGTGCGGACCAGGTCGTCGCGCCACGCCTCGGCGGCCAGCACCTTGGCCTGCGGCTCGGCCTCGGCCATGTAGGCCTGGAAGTCGACGTCGTTGGAACTGATGATCTGGCTCATACCCGAAGCTCCTGTAGGTCGGCGGCCGGATCCCACAGCAGGATCCCCCACTCGCCCGATGCGATCGCCTTAGCGGGCGAGAAGTCGCGGACGCGGCGCAGCAGCTGCATTGCCCTGGAGCGTGACGGCGCAACGATGTGGACGACCAAGCCGACCACGACGCGCAGGTCCAGCGCCGCGGCGTTCTCGTCATCGTGGATGTGGATGTCCGGGAACCCTACCCAGCGCCCGTTCGTCATCTGCCCGAGCTGGGCTTCGGGGTGCGTGAAGCGCCCGCAGGGCTGTTCGGCAGTCAGGCAGGTCAGCCAGACGTCGGTGGGCCGGTAGCCACCCATGCGGGCAGCGATGAGGCTCTGGTGTCCTATCACACTGCCCCCGTCCATGGCTGGTCGCTCCCCAGGGCCCCCTGCAACGCCGCGTCTGCCTTCGGCGGGTAGAACGTGTCCCAGGCATGCAGGATCGACTGGTCCATCATCGTCGCCACGTCGTGGCCAGCAGCTCGCAGCGCGTCCAGCTTTGTCACGGCCAGCTTGCGGGCTGCGTCGGTCATGGGCTTTTTCTTCTTCCGCCGCATTTCCTCGAACTGCCGCCAGGGGTCAGCAGGGATCCAGTCCGGCAGCCTCCAGCCCTCGGCCCCCGGCAGGGGGCTTTGGGGGTTATCTTTTTCTTCTCTACTCTTCTCTTCTCTAGGCGTCACTTTTGCGTCACGCGTTACGTTACGCGTGACGTTACGCGTGACGTCACTTTCTAGCTTCTGACGCTCGCGATAACGCTGCTGTCGAGCGGCTGATTTCGACTTGGGAGACGCGTCCGGATCAACGTTGTGATCCTCAAAAAACCTCGGAAATACAAGGCCTTCCGCAGTGCTGACGACCCAGCCAACGGCCTCCATTGCAGCGCCCATTCCAGGCAGATCGGCAATGTCGTCCAGCACGCTTGTGGTAACGGCGCGACATACAAGATCGGTGCCTTCGGCCTTGCCACGCAGCCGCATGACACCCCATACCGAAACCAGCGCTCCTACCGTTACGTTACGCATAACGTTACGCGTGACGCTCATGTGACGCTGGCAATGTTGATTCACGTAACGCGCGAGTTCGCCGTCTTCGTTCATCAAGATATCGGCCATCACGCAAATTCTTGGATCCCTGTAGAGATCCGTCCGCATCTTGATCCAGTCATTGGCCATTACGCGGCCTCCTTCATCTTGTCGTCGTTCGCGGTCAACTTCGCAGCGCAAACGGGTTCCCACCGCGTGTAGCCCCAGTCCCAGGTGGCACGCTTGTGCTCGCGGTCAAGGCCGCTCTGGTCGTACAGCGTGTGGCAGTGGTAGCAGGCGGGAACGGTGAAACGGTCAGGCACCTTCAGGCCGGTGCCCTTCCCCTGGTTCTGGTGCGCCGGCACGACCGTTGGGTCGCCCTTGTAGCTGCAGCACCCGGCGAATTGCTGGTAGCAGCGCTCGCCGCGGCAAGCGGCCAAGTACTTGGGGTCGTGATAGCCCGGGCGTTTCTTCGGGGCGCGGCGCTTGATGACCGACCTCGACATAGGTGTCGACAACCTCGACATGGGCGTCTTGCGCTGGAGAGGTGTACGGCGCAGCAT

Protein sequences of DBSCAN-SWA_2

>NZ_AP014582|3616141:3638511|3634650_3635091_-|WP_004566298.1|DBSCAN-SWA
MKTPKLLLDRLPSDFHARLENWGEVMRSRPHYAVSPTYEVCRRLAKRAGQGAWGGEEDMRELDESDAGLIEAAWRNSVYRMLHQHRDILRAHYVTRSYWRATCRALDLRSREYDDVLVRAVSNFEDFVARYAVVMHNPAQDRPTTV
>NZ_AP014582|3616141:3638511|3638097_3638511_-|WP_004566304.1|DBSCAN-SWA
MLRRTPLQRKTPMSRLSTPMSRSVIKRRAPKKRPGYHDPKYLAACRGERCYQQFAGCCSYKGDPTVVPAHQNQGKGTGLKVPDRFTVPACYHCHTLYDQSGLDREHKRATWDWGYTRWEPVCAAKLTANDDKMKEAA
>NZ_AP014582|3616141:3638511|3630194_3631247_-|WP_004566294.1|DBSCAN-SWA
MRYSNGVVRRIIALLNRVDIDLAEQVARAMERLPASAFTVARLDAVLKDVRNLNAEAYRQVRGELEKDLRDLAGYEVGYQSQLFESLGIEFTTRGVTAGQVYVGAMAQPFQGRLLREWMAGLESGRASRIRDAVRMGYVEGQTIQQVVQRVRGTRAKGYADGLLEIDRRNAEAVVRTAISHTAGLARDRWYEANDDIIGALVWVSTLDSRTSQMCRLRDGLQYTTDHKPIGHRVPWGAGPGKLHWCCRSGSVPILKGMEDDPLIGTRAAKDYRDSARGKGEQVRATTTYAEWLRRQPAAIQDDILGPTRGALFRKGGVELESFYNDRGVYLTLAELRRKDAAAFARAGVK
>NZ_AP014582|3616141:3638511|3620476_3621010_-|WP_033448593.1|DBSCAN-SWA
MSLEQALKEAYASAPQDRVVFDTLELRHPAFVDPHGEPTAVRVVLGYEDIRARLETEAPLDGGQDVMFQAGAFRFRLPGFEEGQVPSLLIAIDGASEQIVDHVEAAVQSRFPIYVTYRPYLSTDLSMPQMNPPITMELNKVTVTGSSVSGTATLSDVHNWAFPHERYVRERFPGLFR
>NZ_AP014582|3616141:3638511|3632696_3633974_-|WP_004566296.1|terminase|DBSCAN-SWA
MPSLNQPQARFLALPHKFRAFVAGFGSGKTWVGGAGLCRHAWEFPRVNSGYFAPTYGQIRDIFYPTIEEVAHDWGLAAKINESNKEVHLFAGRKYRGTVICRSMEKPGDIVGFKIGKGLIDELDVMKTDKAALAWRKIIARLRHTAPGLINGVDVTTTPEGFKFVYQQFVKQVRERPDLVALYGLVQASTYENGKNLPEDYIPSLRASYPPQLIAAYLRGQFTNLTSGSVYPNFDRRLHHTDAAEEPHEELHIGMDFNVLNMTATVNVIRAGLPLTVGELTKVRDTPEMARMLKERFKDKGHGVTIYPDASGGNTSSKNASESDLSILRKAGFTVRVNSRNPAVKDRINAVNGMLLNDEGARRWLVNTDRCPTLTEALEQQAYDKNGEPDKSTGHDHPNDAQGYFLVHRYPITPTGMSRIKLTGT
>NZ_AP014582|3616141:3638511|3627946_3628216_-|WP_042144828.1|DBSCAN-SWA
MKAKLPIWYLPGPFYRYEQDVKAEAAKAGVRIVDANATEDRKGAAKDVPKVTLKPEYRPKGKAEAAKEKELEPTPKDPDQGSGQGLTAV
>NZ_AP014582|3616141:3638511|3627210_3627411_-|WP_004566290.1|DBSCAN-SWA
MGNFLRLVLPTPTDAPGLQDCRGIRLYTADGAPIPGLVAVKLEAGTDEPIWRATLIMDVNVSGKPD
>NZ_AP014582|3616141:3638511|3629946_3630189_-|WP_033448595.1|DBSCAN-SWA
MPLHLVPDAPKPAETEKDRIRKRIKALPKPKDMIQCHRCGAREVIETRIGVFESGRSWSGGTKVLLCALCFVRGERVVLK
>NZ_AP014582|3616141:3638511|3635967_3636909_-|WP_004566301.1|DBSCAN-SWA
MSQIISSNDVDFQAYMAEAEPQAKVLAAEAWRDDLVRTVEHGDQITGAKLPWSKTHDLLRFRPGEVTLWQGINGHGKSELLGQACIGFATQGERVCIASFEMKPQATLKRMLRQTAMNARPGVQAVDRLIDWSRDRLWLYDQQGTVTPAMLYAVIRYCADRLKVRHMVIDSLMKCVRGEDDYNGQKDFVDMLCTLARDLRMHIHLVHHAKKGENEDQVPGKFSAKGSGAIVDQVDQMLTVWRNKKKERIAEAELRKDGEVSADTHDSPDTLLICDKNRHGEWEGRIQLWRHADSLQFTGDKRRQPLDMIGALA
>NZ_AP014582|3616141:3638511|3626420_3626819_-|WP_004566288.1|DBSCAN-SWA
MSFTADLGKFVARAKGNVDTATRQATVLLAQGVILKSPVDTGRFRANWQFSAAGVQRGTTMAIDPGGQVTLHRLVAEIRQTAAGGVTYLSNSLPYAVRLENGWSKQAPQGMVKLTVQEFQQYVSQAAKDANK
>NZ_AP014582|3616141:3638511|3636905_3637277_-|WP_004566302.1|DBSCAN-SWA
MIGHQSLIAARMGGYRPTDVWLTCLTAEQPCGRFTHPEAQLGQMTNGRWVGFPDIHIHDDENAAALDLRVVVGLVVHIVAPSRSRAMQLLRRVRDFSPAKAIASGEWGILLWDPAADLQELRV
>NZ_AP014582|3616141:3638511|3635287_3635971_-|WP_004566300.1|DBSCAN-SWA
MTHVDLIAGQPAGVPLDPLAGTLAGSHARVPTFDLEKINTDVADPWARGGAETAPDAAPRRANAGSTVVPELGPNVTILALDLGTKLGWAVRGRDGRTSHGTEVFTPRASWSPGQRWLRARSFLVEVITQRQVHAIAYEDVKRHTGTDAAHAYGAFLCIVEMLADSHRLRLLPVGVGTIKKHWTGKGNADKADMIAEAKARGFRPETDNDADALAILSWAVAQERAA
>NZ_AP014582|3616141:3638511|3626815_3627211_-|WP_004566289.1|DBSCAN-SWA
MATFDYADMAATAQELLDEFGGPVTVRQIVTGEYDPDLGQASTTTVDNDGIGALFDYTAQAAGLANMAGSVIETGDKQMYLAPELAAGGAMPEPKPADLVLALGATWRVVTVKTLAPAGLVLLFELQLRQA
>NZ_AP014582|3616141:3638511|3624073_3624364_-|WP_003813411.1|DBSCAN-SWA
MYRPMPDKAQLAEFGLRPDDFPAAVIELWPDNVMPKVVFEAMGSQWRIGFAGPTGLDYGALAGVMRMLGVPPEQEIDVFDGVRVMESAALRMMNKK
>NZ_AP014582|3616141:3638511|3620090_3620480_-|WP_004566282.1|DBSCAN-SWA
MTSSDVNRYIGLMWRLGGRGPDAYDCWGLLRECRERYFEGGIPETALGEQARALYAHKMRTGAWKIVTHPQHGDGVMLRAGNDPHVGIYLDLDGGGVLHALEGRGVIFSPMRALFTMGFSQPIFYRIHA
>NZ_AP014582|3616141:3638511|3637273_3638098_-|WP_004566303.1|DBSCAN-SWA
MANDWIKMRTDLYRDPRICVMADILMNEDGELARYVNQHCQRHMSVTRNVMRNVTVGALVSVWGVMRLRGKAEGTDLVCRAVTTSVLDDIADLPGMGAAMEAVGWVVSTAEGLVFPRFFEDHNVDPDASPKSKSAARQQRYRERQKLESDVTRNVTRNVTRDAKVTPREEKSREEKDNPQSPLPGAEGWRLPDWIPADPWRQFEEMRRKKKKPMTDAARKLAVTKLDALRAAGHDVATMMDQSILHAWDTFYPPKADAALQGALGSDQPWTGAV
>NZ_AP014582|3616141:3638511|3625493_3625994_-|WP_004566286.1|DBSCAN-SWA
MNEARITAERLRSVVHYDPETGKFTRLVRLAQRHNVGDDAAHATANGYQRVGIDGQRYLAHRLAWLYMHGAWPTQHIDHMNGDRSDNRIANLRDVPQAVNMQNRRHPQADNKSGYLGVYWERGAKKWRSRVQVAGKAHEVGLFDDPAVAHAAYVAKKRKLHEGCSI
>NZ_AP014582|3616141:3638511|3621076_3621436_-|WP_010926426.1|DBSCAN-SWA
MPLPVWPAGLPLVEFSRQPISPFQRTEMDSGRSRHRRHSRVYPIHAPVSFVLDGDQYDAYQRFCSIDLNGYAGWFLMAINGPGGLKLRKVRWLLPVPREERIPGDLWRVSGQLETMSDA
>NZ_AP014582|3616141:3638511|3628225_3629194_-|WP_004566292.1|DBSCAN-SWA
MSISQMQVFNKYFMPAIIETLGQQIQKFNAASRGAIMLTTAGFEGDFLQESFYQAIHGARRRVDRYAANGSASPTDLTQLKHSSVKVAGGFGPIRYEPSQMTWLEKPTAEGIEVASRHFAEALLQDQLNTAIAALVAAISNQALATVNVSAKTGLNYSVLNDAHAKFGDSSGLIVANVMSGQVYHKLIGQNLVNAQQLFEYGAVTVVDILGKTVVVTDAPALYATGTPNLQKVLGLVAGAATVSDGGDLITNIETSNGKERIETTFQADYTFGLGLKGYTWDEATGGKSPTDAELATGTNWDKVATDIKHTAGVIAIGDASK
>NZ_AP014582|3616141:3638511|3625237_3625393_+|WP_157835999.1|DBSCAN-SWA
MIRIVPAFGGLVALATAGLALVIAETATAAPNPVDTEKTVPLGNIALMIVP
>NZ_AP014582|3616141:3638511|3631275_3632694_-|WP_004566295.1|DBSCAN-SWA
MPVDSKHPLWTASQPRWERCRTALQGQDAVHAAGTKYLPKLAGQEQEEYDAYKGRALFYGATARTEEALIGMVFRKEPTVTLPAALQPMIEDADLAGTPVDTFIENVVKEVIDVTRVGVLVDYPVASGEFMTVGQAQAVGLRPYLATYKAEAIINWRTARVSGVNQLVLVVLAETYTEQKDEFTAEEKTQYRVLDLADGAYRVRIYRTDLNTPAFEYTPMMNGKRLPYIPFVLIGRNGEAIDPQKPVLLDLVDVNMSHYRGTADYEHALHFTALPTAVVTGHELQAGQSLKIGSSEAWVFSEAEARAQYLEFSGQGLDSIKVSLERKEGMMATLGARILAPEKRDAEAAETAKIHRAGENSVLGGIALGVGRSLAKAFRWAAEWAGAGSGTVEVKLNTEFFPVGLTAQDLTALVGALQAAAISPETFYDNMRRGGIIDDGVTFEEEQARIEAAGPALGTLGGQDGQPANRAV
>NZ_AP014582|3616141:3638511|3626001_3626424_-|WP_004566287.1|DBSCAN-SWA
MSQDLIRAAFEKRLSDWAKARTPALPVAWQNTKFTPPAAGVYLRAYVMPAATISRDAAGDHRQYRGVFQVNVVMPIGDGSRSAEQVAAELDALFPVNLVMQSGGLAVRVRTPISNGQPTTGDADHTVPISLGYDVQFYPE
>NZ_AP014582|3616141:3638511|3616141_3620098_-|WP_004566281.1|DBSCAN-SWA
MPDITIQRDPFRPHLRQETIVAPQGVRLDTVLRREGFIVGRGKSLVRTRTFVVQLNGSWKVQSAWHVRLRKHDVVAVVVLPAGGGGSNPLQVVAMAALAAATAGVGAWAASAYAGAAGVAATSAAALTVGAGAATAVGLVGGMVVNSLFPPARLPGSLQREKASPTYTLSAQGNMARPMEAIPARYGRYRSYLDFAAQPYTEMVNNQTHLYQLFCVGQGRYEIEEIRIEETPIGNFSEVEYEVVEPGGQVTLFPDNVVTSAEVQGIELPAINVEGAGPKGPFAANPPGTLASEIAIDILLPKGLFYAAHDGTLESAGTGVNVYARQIDDSGKPIGTTIVLGRENIVAATLTPQYRTFRYKVEPGRWEISVERNSGHLAERATRMIRDVTWLGLRSYLPSQRTYGNVTMLAVAMRATGNLNQTTARRINIIATRRLRTWDPVQGWSQDLKPTRNPAWAIADACTDREYGRGLPDSRINLAALYRLAKVWDERGDWFDGVFDVSTTFWEAVTQIARAGRALPIYHAGVIDVIRDEPKSVRTQMFTPANIVTRSFSVDYVFPAHDDPDYIIVEFVNERTWKDDEVECAWPGAAKRRPYRLRLVGVTGRAQAWREGMALLARNRDQRRFASFQTELEGAIPGYADLVEISHDVPKWGLSGIVEDYDPRALLLTTSEPLQWWQGQNHYISLRGRDGGPAGPFRVEPGSHEREMRIADLVDGHGLYISTGETEEPTHYTFGPGERRALLAQVMRAVPSEGGLWTLDLVNYAPSVHTAELGGQEPEFASPSLLPIVPLGPIVDGVTVFSAPRPGQQIVSATPASGAYRYEFEASDDGGVHWQPLGMAELPSLEVHLRAGSWQVRVRGVGALSGPWKTWQGNVSASAAPPPRLSALTAVSQVMAIELAWTVPDAPWISSVEIWESSTSNLGDASLMGEFRLPQSRFTRFGLSHGTRIWFWGRIRDEAGQVGPWYPDGQGVPGSASSDAGKILDYLSGQIGPEQLTRDLTQTISGMGRNINTVTAKLDQEREERLNQDGALARRVEDAIAANGASATAVKQTSTALSSLDGRLRATWSVQTQVAQDGKVYAAGMALGAYTNERGRVQTSVYFLADRFAFLNLANGKISTPFVVQNGQTFLNKAFIGTAWIKSAQIESLDAGKIVVGVMSADRINAESLIAKLASFTTAYVKTAHIGVAQVDTLRLASGAVVTGSHSIISKSLGRGGSELATVATGSLYLPYGGSVVVFMQYAQSGGRFPFGRNTIVSIDGEIIPNALSNPPDGAAMITWISDALPGGKTISWSIKARHPVDGTYYIGGRVAVLAIQR
>NZ_AP014582|3616141:3638511|3624381_3624711_-|WP_003813412.1|tail|DBSCAN-SWA
MSNIIFKLQPAPTFTVPVEIPRHGEEPANIKVTFRHKSRDEMKDFLERADKSDASQDIALVNEMIAGWDGPDMEFSDEAVGLLIQNYQGAVPALVQAYSLELLQARRKN
>NZ_AP014582|3616141:3638511|3624723_3625239_-|WP_003813414.1|tail|DBSCAN-SWA
MKSGWPELNERVVRAVNTASNTFALEGIDTTKVGRFSKGQGIGTATPVSTWVDLSQVTNVAKTGGEQQFYQWRYVEDRNSRQRQRPTYKSAKFITLTLDYDPALAWYEALKEADAAKDAVVLRAKLPNHDELYYLVYPSFDSDPSMELDVNMQNTATFSMMSDFTRYAPLA
>NZ_AP014582|3616141:3638511|3633960_3634332_-|WP_004566297.1|DBSCAN-SWA
MARPKKELPDLGQIEALASKGLNEEQIASALGISYSTLRRHKASNEQLQAALKKGKALGIADVSSALYDAAVGGNVTAMIFYLKNRSPDSWRDKPDSTNDDNAPPPVKVVIEVKDASVPDAEP
>NZ_AP014582|3616141:3638511|3621445_3624046_-|WP_042144822.1|tail|DBSCAN-SWA
MADEVASLVLRVDSTQVKGASTDLDKLAAAGAKAEQATVKVGTAGKAAATGLGAMGKAAKAAQAQTAAATLSVGEMRTAMRSLPMQMTDIAVGLSTGQSPFYVLLQQGGQLKDLFGGIGPAIKAVGGYVASLITPFTAAAAGAVALAVAYQQGAEEGRRFTAAITLTGNAAGVTESQLAAMANRISDIQGTTGNAAAALTKLVETGKIAGDSIEGLGRAAVLAEAATGRSVDEMVKDYERIADAPAEALTKLNERYHFLTLAVYDQVKALEAEGRTQDAARLALNTYAQAMEERYPQVVENIGDLERAWKAVTDVAKGAWDAMLAVGREEALEQKLAQARKNLQSLETSRFRTFLDDDRIKQLRGEIAGLEELDKWQKAAAKSRADQAGAVARGIQARKDLDSYLESHKGASLAASMEAENAAFKKATAEFKQNSDEYKKALKLHVARVAQIQRQFAGSKGAVAPGVRELERAREQEAALRAQLESAVKITSARQELVKFEQRIADLKARDQLSADEKSVLANEQALRQQLELNAGLADQITLKKEAVQLKVLERSAQETLIADQQRYNDLLAGLTASPRLREQLHAQQQIYRDFQRQVQRAAEQNEAKEITPQAYADRVRVLKQSLERRLELLADHYNKARLLEKDWKEGARQAFNDYAELVSDVAKLTRSAFANAFSGAENALVKLVVTGKARFADFADSIIADLTRISVRQSITGPLASALGSVFRNAFGSALPATASWAMPELAGRRAMGGPTLPRRLYEVAENGPELYDEGGRTYLLAGGDGGHVTPLTHSSYRPSTPVTVNLHGVESQPQVRARPDARGGLTLDLIFRQVKDQLAHDIDSGMGSLPRALERRYGLSRQLA
>NZ_AP014582|3616141:3638511|3627412_3627895_-|WP_004566291.1|DBSCAN-SWA
MPLIVEDGSGLANADSYVSVADCQAYAADHGLAFAGEAAALEAALRNATLYLDGEYTYRGERATDIQALEWPRTVATGVPREVVNACCELAARALKSPLWQDVSGTTVGAAIEKTVGPITTKYANAAGARNDGQTRYAGVTAMLRRWLSSYGSSVKLVRC
>NZ_AP014582|3616141:3638511|3629220_3629823_-|WP_004566293.1|DBSCAN-SWA
MPLDRNDPEVKALIEEVTAEATEALSAKNKELIAELRTAKAKAKGSEIDPEEHARLQTQVEELTGKLEKATKDSARQIEKLTKDLTEKEGALTQHLIDGGLSTALAKAGVAPHFMDAVKAMLRSQTSIKDGAAVIGDKLLDDHVMEWASTDQGKHFITAPANTGGGGQGGNGGGKCTGNMGGSREDRVAALKAKFPELSG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004566281.1|3616141_3620098_-	DUF1983 domain-containing protein	A0A0B5A1N2	Achromobacter_phage	1.2e-219	41.1
WP_004566282.1|3620090_3620480_-	C40 family peptidase	A0A0G3EYJ9	Achromobacter_phage	3.3e-34	49.2
WP_033448593.1|3620476_3621010_-	DUF1833 family protein	A0A0B5A6T7	Achromobacter_phage	1.2e-47	56.5
WP_010926426.1|3621076_3621436_-	hypothetical protein	NA	NA	NA	NA
WP_042144822.1|3621445_3624046_-|tail	phage tail tape measure protein	A0A1V0E821	Vibrio_phage	4.5e-103	36.4
WP_003813411.1|3624073_3624364_-	DUF1799 domain-containing protein	A0A2H4JBP7	uncultured_Caudovirales_phage	6.3e-14	41.9
WP_003813412.1|3624381_3624711_-|tail	phage tail assembly chaperone	A0A2H4J121	uncultured_Caudovirales_phage	2.9e-15	44.0
WP_003813414.1|3624723_3625239_-|tail	phage tail protein	A0A1S5R1H0	Pseudomonas_phage	1.2e-23	38.3
WP_157835999.1|3625237_3625393_+	hypothetical protein	NA	NA	NA	NA
WP_004566286.1|3625493_3625994_-	HNH endonuclease	A0A1I9SEX5	Klebsiella_phage	7.5e-31	45.1
WP_004566287.1|3626001_3626424_-	DUF4128 domain-containing protein	NA	NA	NA	NA
WP_004566288.1|3626420_3626819_-	HK97 gp10 family phage protein	S4SIM9	Salmonella_phage	2.1e-23	44.9
WP_004566289.1|3626815_3627211_-	hypothetical protein	A0A2D2W284	Stenotrophomonas_phage	7.8e-07	35.0
WP_004566290.1|3627210_3627411_-	hypothetical protein	NA	NA	NA	NA
WP_004566291.1|3627412_3627895_-	hypothetical protein	A0A2H4JE38	uncultured_Caudovirales_phage	2.6e-12	38.5
WP_042144828.1|3627946_3628216_-	hypothetical protein	NA	NA	NA	NA
WP_004566292.1|3628225_3629194_-	hypothetical protein	R9TJ64	Synechococcus_phage	6.6e-124	71.7
WP_004566293.1|3629220_3629823_-	hypothetical protein	R9TF81	Synechococcus_phage	5.5e-28	44.3
WP_033448595.1|3629946_3630189_-	hypothetical protein	A0A0H5AUE5	Pseudomonas_phage	1.9e-16	51.9
WP_004566294.1|3630194_3631247_-	hypothetical protein	A0A0H5BBX3	Pseudomonas_phage	6.3e-96	50.8
WP_004566295.1|3631275_3632694_-	DUF4055 domain-containing protein	R9TF43	Synechococcus_phage	1.2e-97	41.5
WP_004566296.1|3632696_3633974_-|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	9.2e-150	64.2
WP_004566297.1|3633960_3634332_-	DNA-binding protein	A0A090DCM3	Clostridium_phage	6.2e-06	36.7
WP_004566298.1|3634650_3635091_-	hypothetical protein	NA	NA	NA	NA
WP_004566300.1|3635287_3635971_-	hypothetical protein	K4ICN3	Acidithiobacillus_phage	4.9e-33	50.0
WP_004566301.1|3635967_3636909_-	AAA family ATPase	A0A0U4B0G9	Pseudomonas_phage	8.5e-52	36.5
WP_004566302.1|3636905_3637277_-	hypothetical protein	NA	NA	NA	NA
WP_004566303.1|3637273_3638098_-	hypothetical protein	R9TJW3	Synechococcus_phage	1.9e-07	45.3
WP_004566304.1|3638097_3638511_-	DUF1364 family protein	A4JX58	Burkholderia_virus	8.1e-15	39.1