CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007512	Bacillus bombysepticus str. Wang chromosome, complete genome	2 crisprs	csa3,WYL,DinG,cas14j,cas3,DEDDh,cas14k	0	2	10	0
NZ_CP007513	Bacillus bombysepticus strain wang plasmid pBb, complete sequence	0 crisprs	cas14j,csa3,PD-DExK	0	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007512_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007512_1

4653958-4654076

Orphan

Consensus_repeat	Method
GTTTCTTCCTACCGAACATACAGCTTAAACAAACGTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007512_1

>merge|NZ_CP007512|1|4653958-4654076|CRISPRCasFinder
GTTTCTTCCTACCGAACATACAGCTTAAACAAACGTTTGATTAATTCTCCATTTCTCTTTGTTAACCCTTGAGTTACATCGGTTTCTTCCTACCGAACATACAGCTTAAACAAACGTTT

>NZ_CP007512|1|1|4653958-4654076|CRISPRCasFinder
GTTTCTTCCTACCGAACATACAGCTTAAACAAACGTTT	GATTAATTCTCCATTTCTCTTTGTTAACCCTTGAGTTACATCG
GTTTCTTCCTACCGAACATACAGCTTAAACAAACGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007512.1\|WP_000713763.1\|4654777_4655425_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239481
NZ_CP007512.1\|WP_044584958.1\|4654115_4654634_-\|lipoprotein	unknown	unknown	unknown
NZ_CP007512.1\|WP_002001391.1\|4656526_4657720_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|133427
NZ_CP007512.1\|WP_030029140.1\|4659536_4660259_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293807
NZ_CP007512.1\|WP_000074949.1\|4658984_4659533_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP007512.1\|WP_001242139.1\|4651383_4651728_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007512.1\|WP_000026896.1\|4652913_4653297_-\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP007512.1\|WP_000735086.1\|4648323_4649136_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP007512.1\|WP_000640870.1\|4652192_4652537_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224572
NZ_CP007512.1\|WP_000218968.1\|4653338_4653704_-\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP007512.1\|WP_030029143.1\|4660398_4662183_-\|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|173850
NZ_CP007512.1\|WP_076774618.1\|4651880_4652189_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP007512.1\|WP_001206346.1\|4662518_4663691_-\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|181072
NZ_CP007512.1\|WP_000359401.1\|4649158_4649824_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP007512.1\|WP_000152167.1\|4645991_4647284_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP007512.1\|WP_001180555.1\|4657986_4658172_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007512.1\|WP_001002987.1\|4657724_4657973_-\|spore-coat-protein	unknown	unknown	gnl\|CDD\|377935
NZ_CP007512.1\|WP_000929160.1\|4647299_4648085_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP007512.1\|WP_000601781.1\|4649816_4650842_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP007512.1\|WP_044584959.1\|4655490_4656504_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|379113

Protein	Function_ID	Function_description	E-value
NZ_CP007512.1\|WP_000713763.1\|4654777_4655425_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|239481	cd03386, PAP2_Aur1_like, PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin.	5.79951e-16
NZ_CP007512.1\|WP_000735086.1\|4648323_4649136_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	4.41843e-113
NZ_CP007512.1\|WP_002001391.1\|4656526_4657720_-\|L-lactate-dehydrogenase	gnl\|CDD\|133427	cd05291, HicDH_like, L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases. L-2-hydroxyisocapronate dehydrogenase (HicDH) catalyzes the conversion of a variety of 2-oxo carboxylic acids with medium-sized aliphatic or aromatic side chains. This subfamily is composed of HicDHs and some bacterial L-lactate dehydrogenases (LDH). LDHs catalyze the last step of glycolysis in which pyruvate is converted to L-lactate. Bacterial LDHs can be non-allosteric or may be activated by an allosteric effector such as fructose-1,6-bisphosphate. Members of this subfamily with known structures such as the HicDH of Lactobacillus confusus, the non-allosteric LDH of Lactobacillus pentosus, and the allosteric LDH of Bacillus stearothermophilus, show that they exist as homotetramers. The HicDH-like subfamily is part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP007512.1\|WP_000074949.1\|4658984_4659533_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	4.99056e-26
NZ_CP007512.1\|WP_000026896.1\|4652913_4653297_-\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	6.96592e-70
NZ_CP007512.1\|WP_000218968.1\|4653338_4653704_-\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	6.13259e-61
NZ_CP007512.1\|WP_000640870.1\|4652192_4652537_-\|hypothetical-protein	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.03274e-21
NZ_CP007512.1\|WP_030029143.1\|4660398_4662183_-\|acyl-CoA-dehydrogenase-family-protein	gnl\|CDD\|173850	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase. VLCAD is an acyl-CoA dehydrogenase (ACAD), which is found in the mitochondria of eukaryotes and in some bacteria. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. VLCAD acts as a homodimer.	0
NZ_CP007512.1\|WP_076774618.1\|4651880_4652189_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	9.26936e-18
NZ_CP007512.1\|WP_001206346.1\|4662518_4663691_-\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|181072	PRK07661, PRK07661, acetyl-CoA C-acetyltransferase.	0
NZ_CP007512.1\|WP_000359401.1\|4649158_4649824_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	8.57648e-99
NZ_CP007512.1\|WP_000152167.1\|4645991_4647284_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	3.81959e-130
NZ_CP007512.1\|WP_030029140.1\|4659536_4660259_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293807	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain. This subgroup includes the uncharacterized Bacillus subtilis yflN protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	6.42669e-72
NZ_CP007512.1\|WP_001002987.1\|4657724_4657973_-\|spore-coat-protein	gnl\|CDD\|377935	pfam07875, Coat_F, Coat F domain. The Coat F proteins, which contribute to the Bacillales spore coat. It occurs multiple times in the genomes it is found in.	9.62029e-15
NZ_CP007512.1\|WP_000929160.1\|4647299_4648085_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	8.75164e-150
NZ_CP007512.1\|WP_000601781.1\|4649816_4650842_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.11315e-176
NZ_CP007512.1\|WP_044584959.1\|4655490_4656504_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|379113	pfam13303, PTS_EIIC_2, Phosphotransferase system, EIIC. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.	4.95257e-87

>NZ_CP007512.1|WP_000218968.1|4653338_4653704_-|arsenate-reductase-family-protein
MTVTFYSYPKCGTCQKAKKWFEANDVAYEMIHIVENPPSKEDLRNLHEKSELPLKKFFNTSGMRYRELGLKDKLKDASEDEMYELLASDGMLIKRPIVTDGTNVTLGFNEEQFESVWKKYQ
>NZ_CP007512.1|WP_000026896.1|4652913_4653297_-|glycine-cleavage-system-protein-GcvH
MSIPNNLRYSEEHEWVKTEGNEVVIGITHFAQGELGDIVFVELPEVGATIEADEPFGSVESVKTVSELYAPVSGKVVAVNEELSDQPELVNESPYEGAWMVKVELSDASQVEKLLTAEKYAEMTNQD
>NZ_CP007512.1|WP_000640870.1|4652192_4652537_-|hypothetical-protein
MIYVEKVIIVEGTSDRRKIESIIREPVEIVCTNGTIGLSKMDELVDQFFDKEVYVLVDADDAGEKLRKQFRKEFPQAEHIYIDRSYREVATAPSTHLANVLWGADIDVYTEYLR
>NZ_CP007512.1|WP_076774618.1|4651880_4652189_-|thioredoxin-family-protein
MIEVIDWTGAEATALIENEEKIVLYVYTPMCGTCQLAKKMLTVVEMTIEGLKIGMLDLNYAPYLAKEYGIESVPCLLVFENGTLMKKIYAFHSVEYLYTELK
>NZ_CP007512.1|WP_001242139.1|4651383_4651728_-|hypothetical-protein
MRLYSLLQSFVNYANGQYHLEPLLRQEEKTVNFRFGDESCSLQISRDYIELVHEERGTEQIICLDEKDIEQLVNGNVRLQMLMNDGRVQYSGTYRTMLLVESMFHICKPMSVGA
>NZ_CP007512.1|WP_000601781.1|4649816_4650842_-|methionine-ABC-transporter-ATP-binding-protein
MILLENVKKIYKAKSGDVTAVDNANLKIEKGEIFGVIGYSGAGKSSLIRLFNQLEKPTSGQITIANRVISAITGSELRKARQEIGMIFQHFNLLWSRTVRENIEFPLEIAGVDKAQRRKRVDELIHLVGLEGRGDAYPSQLSGGQKQRVGIARALANNPQVLLCDEATSALDPETTDQILDLLLDINKRLGLTIVLITHEMHVIRKICNRVAVMERGKIVETGPVLDVFRNPKQDITKRFVQQLTDSEDTNETIESLIEKYPDGKVIRLQFIGEAVERPVLQRLMQRSDIEVSILQGNIAQTNNGSYGSLVVHLNGEETAIQQAIEGIHQDQVELEVIAHG
>NZ_CP007512.1|WP_000359401.1|4649158_4649824_-|ABC-transporter-permease
MDKLLANVDWNQMLEATGETLYMTAIAALATFVLGLILGLLLFMTAKDNLWENKSINTVIGAFVNIFRSIPFIILIILLIPFTKILLGTILGASAALPALIIGAAPFYARMVEIALREIDKGVIEASKAMGAKTSTIILKVLIPESLPALVSGITVTTIALVGYTAMAGVVGAGGLGTLAYLEGFQRGNNDVTIVATICVLLVVFLIQWIGDSLTTRIDKR
>NZ_CP007512.1|WP_000735086.1|4648323_4649136_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLLLTALISTSIFGLAACGGKDKDEKKLVVGASNVPHAEILEKAKPLLEKKGIELEVKKFQDYVLPNKSLADKDLDANYFQHIPYLEKEIKDKKYDFEIAGKIHIEPIGVYSQKYKSLKELPDGATIIMSNSVTDHGRGLAILQKEGILKIKDGVDPVSATPKDIADNPKNLKFKTDIEPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIEGDDSPYANVVVVRKGDKDKKAIKELVEVLHSKEIQDFITKEYKGAVLPISE
>NZ_CP007512.1|WP_000929160.1|4647299_4648085_-|Fe-S-cluster-assembly-ATPase-SufC
MAGSTLTVKDLHVSIDGKEILKGVNLEVKGGEIHAIMGPNGTGKSTLSSAIMGHPKYEVTEGSIIIDGEDVLEMEVDERAQAGLFLAMQYPSEISGVTNADFLRSAINARREEGDEISLMKFIRTLDKNMEFLEMDPEMAQRYLNEGFSGGEKKRNEILQLMMIEPKIAILDEIDSGLDIDALKVVSKGINEMRGEEFGCLMITHYQRLLNYITPDFVHVMMNGRIVKSGGPELAQRLEAEGYDWIKKELGIEDETTEQEA
>NZ_CP007512.1|WP_000152167.1|4645991_4647284_-|Fe-S-cluster-assembly-protein-SufD
MTIGTLPFDQETIRQRASEVNEAAWLTEFRLQALAQATELPMPTPDKTKIDKWDFIGKGDAAKQEPVSSLTELPEAVKNLIDENNSVLVQRTGTTAFVSLADEAKEKGVIFTDIVTAATEHAELVQKYLMKDGVKVDEHRLTALHAALINGGAFVYVPKNVVLETPLQAVFLVDGEEANVYNHVLFVADANSTATYVENYVANENAKGIANIVAEVIVEQGAQVKFGAVDLLAKDVTTYVNRRGVVGRDGRIDWALGLMNDGNTISENVTNLMGDGSYADTKTVTIGRGNQTQNFTTKVVHFGKHSEGWILKHGVQKDSATSIFNGIGKIEHGASKSNAQQSSRVLMLDEKARGDANPILLIDEDDVMAGHAASVGRVDPVQLYYLMSRGIPKREAERLVIHGFLAPVVNELPIEGVKAQLVEVIERKVR
>NZ_CP007512.1|WP_044584958.1|4654115_4654634_-|lipoprotein
MKRLSYFLFFILICLVGAGCAKDKEGEKLEYNGRALVIGVVGEKPKDTFRNVKFEEMKLEALEKKSKEVDGFLIMKDHFQEASTEQYKNVFSSLKKPVFFIGLQDKSYSIFITKGIEYNSARKDVNAMYTQGFANIGSGEGQQWAIGLSNGGESIHNMYIVVFQTIADYLNR
>NZ_CP007512.1|WP_000713763.1|4654777_4655425_+|phosphatase-PAP2-family-protein
MKKFKLSSFLPLSYILLLVLVSPLYDVLNKSTVHAVDVTTVVDDWIPFVKAFIIPYLLWFPYLYGALIYYCFADRKQYYVTLSSIIFGKLACFSIYYFWQTTVPRPTVVGTDVFSELVRYIYSIDQPVNCFPSIHVLTTFVIMLAAFKRREQHAFEYYILTFFGTLIILSTLFTKQHAFVDAVSGMTLASILYFGVQLLLAKEPIRVPVKQNHRM
>NZ_CP007512.1|WP_044584959.1|4655490_4656504_-|PTS-sugar-transporter-subunit-IIC
MKEYIMSRVFKASAGIAQGIFVSLGIGLLIENIGRIVDIPLLITIGVVAKSLMAPAIGAGIAFMLGANGLVIFSAMVAGAIGAGSISTTEAGLIIKTGEPIGALLTATLAVYIGKRLSGKTALDMMLVPFAAILGSGLVGIWLSHNITPVLNTVGAFIKDSSAGSPFIASIVIAVVWGLLLISPASSAALAIALSLDGVAGGAALAGCVAQFIGFSVISAKENNLGGILAQALCTPKVQLPNITKNPMILVPTVVASAIVGPVSALIFQLEAGKEIAGLGLSSLIAPINLISSQGWEVLPAMVITYIVIPVAVSYILYIALKKAGRIHSGDMTVPQS
>NZ_CP007512.1|WP_002001391.1|4656526_4657720_-|L-lactate-dehydrogenase
MTKNGRMKSLVFCFEHVNKYKINIFPVVTNMTKMEYNNSQKGQILCSIFHKVSMVSIVGTSIIRSVKSKRNRLYDQLGEIAMKRHTRKIAIIGTGLVGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYEDCKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDIITYEVWKLSGLPRNRVIGTGTSLDSSRLRTILSEMLHVDPRSIHGYSLGEHGDSQMVAWSHVTVGGKPVLQILEEQKERFGEIDLDEIVEKTAKAGWEIYKRKGTTYYGIGNSLAYIASSIFNDDHRVIAVSAILDGEYGEYDICTGVPAIITRDGIREVVELNLTEDEESRFAKSNDILRDYMKTIGY
>NZ_CP007512.1|WP_001002987.1|4657724_4657973_-|spore-coat-protein
MNEKDMVNDYLAGLNASLTSYANYIAQSDNEQLHQTLIQIRNQDEMRQRNMYEYAKQKSYYKPAAPANPMIVQQLKSQLSAE
>NZ_CP007512.1|WP_001180555.1|4657986_4658172_-|hypothetical-protein
MQNLTELEVENLRHLIGGHATIINKLEQYAQTCTDPQLKQMLQKDAQDARNTKQQLMTFLG
>NZ_CP007512.1|WP_000074949.1|4658984_4659533_-|TetR/AcrR-family-transcriptional-regulator
MSPRIGLTLQKIVETATEIADTNGIQEVTLASLAQRLGIRSPSLYNHVKGLQDVRKNLGIYGIKQLHNKLEEAAEDKRMDEAIHALGEAYVAFVRKHPGLYEATFLRDEEVRKAGDGIVKLCLQVLQQYGLEGENALHATRGFRSICHGFASIEQQGGFGLPLDLDISLHVLLETFIKGLRE
>NZ_CP007512.1|WP_030029140.1|4659536_4660259_-|MBL-fold-metallo-hydrolase
MRMIHEKTLYQLSFLPRAFPVNCYFVEEEDGLTLIDAALPYSAKGILQAAEKIGKPITKIVLTHAHDDHIGALDALKEVLPHVPVYISKRDAKLLEGDTTLQKDEPNIPIKGGVPKKVKTVPDVLLEDGDRVGSLLAIMTPGHTPGSMSFLDVRNKALIVGDAFQTRGGMAVSGQMKFWFPFPAMATWSKEISVQSAEKLSEYEPSLLAAGHGKMIKNPGTVIELAIKEAKRNIESKKEG
>NZ_CP007512.1|WP_030029143.1|4660398_4662183_-|acyl-CoA-dehydrogenase-family-protein
MEKTVGNAVKGGSFLVDEITIDQVFTPEDFSSEHKMIAKTTEDFIVNEVLPELEYLEQHEFDRSVRLLKEAGELGLLGADVPEEYGGIGLDKVSSALIAEKFSRAGGFAITHGAHVGIGSLPIVLFGNEEQKKKYLPLLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFVVYAKIDGEHFSAFIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLLGEIGKGHIIAFNILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTYAAESSVYRTVGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQIHGGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIVPGTFLRKAMKGELPLLQKAQKLQEELMMMMPEEVGDEPLALQKYLVTNAKKIGLMVAGLAAQKYGKALDKEQEILVNIADIVSNLYAMESALLRTEKAIKTTGLEKNKQKVLYTEVFCQEAFNEIEADAKETLIAVENGDMLRMMLSSLRKLTRHTPLNVIPKKREIAAKILEDERYTV
>NZ_CP007512.1|WP_001206346.1|4662518_4663691_-|acetyl-CoA-C-acetyltransferase
MREAVIVAGARTPIGKAKRGSLKTVRPDDLGALVVKETLKRANYEGPIDDLIFGCAMPEAEQGLNMARNIGGLAGLSYDVPAITINRYCSSGLQSIAYGAERIMLGHSEAVLSGGAESMSLVPMMGHVVRPNSRLVEAAPEYYMGMGHTAEQVAVKYGISREEQDAFAVRSHQRAAKALAAGNFVDETVPVDVTLRSVGSNNKLQEETITFAQDEGVRAETTLDILGKLRPAFNVRGSVTAGNSSQMSDGAASVLLMDREKAVSDGMKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGLFELNEAFASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVTMCIGGGMGAAGVFELL

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Crispr_ID: NZ_CP007512_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007512_2

4926380-4926513

Orphan

Consensus_repeat	Method
GTTGATTTCTCTTCTTTTTGAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP007512_2

>merge|NZ_CP007512|2|4926380-4926513|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGGTTCTTCTTTTTTGTCACTAGTTGAACCGCTTGTTGATTTCTCTTCTTTTTGAGACTTGTCTTCTGTTTTACTTTCTGGTTTCGTGCTCGTTGACTTCTCTTCTTTTTGAGA

>NZ_CP007512|2|2|4926380-4926513|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGG	TTCTTCTTTTTTGTCACTAGTTGAACCGCTT
GTTGATTTCTCTTCTTTTTGAGA	CTTGTCTTCTGTTTTACTTTCTGGTTTCGTGCTC
GTTGACTTCTCTTCTTTTTGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007512.1\|WP_044585013.1\|4918036_4918720_-\|sugar-transferase	unknown	unknown	gnl\|CDD\|376775
NZ_CP007512.1\|WP_044585015.1\|4920738_4921440_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP007512.1\|WP_044585014.1\|4918737_4919619_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP007512.1\|WP_000057889.1\|4935549_4935786_-\|DUF1146-domain-containing-protein	unknown	unknown	gnl\|CDD\|227173
NZ_CP007512.1\|WP_044585021.1\|4937510_4939013_-\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
NZ_CP007512.1\|WP_044585018.1\|4929128_4930136_-\|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP007512.1\|WP_000544012.1\|4925476_4925749_-\|sporulation-transcriptional-regulator-SpoIIID	unknown	unknown	gnl\|CDD\|378813
NZ_CP007512.1\|WP_044585111.1\|4919859_4920627_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP007512.1\|WP_000931959.1\|4923452_4923887_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NZ_CP007512.1\|WP_000144443.1\|4927401_4928106_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP007512.1\|WP_000457978.1\|4924314_4925316_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237563
NZ_CP007512.1\|WP_000367487.1\|4935988_4937509_-\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
NZ_CP007512.1\|WP_016123874.1\|4930788_4931592_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226297
NZ_CP007512.1\|WP_044585016.1\|4921429_4922173_-\|capsular-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453
NZ_CP007512.1\|WP_000170864.1\|4928105_4928948_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP007512.1\|WP_044585017.1\|4922431_4923109_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP007512.1\|WP_000411274.1\|4933449_4934754_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NZ_CP007512.1\|WP_000008903.1\|4926057_4926192_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007512.1\|WP_002005985.1\|4934793_4935504_-\|YwmB-family-TATA-box-binding-protein	unknown	unknown	gnl\|CDD\|370056
NZ_CP007512.1\|WP_044585020.1\|4932223_4933243_-\|stage-II-sporulation-protein-D	unknown	unknown	gnl\|CDD\|274332

Protein	Function_ID	Function_description	E-value
NZ_CP007512.1\|WP_044585013.1\|4918036_4918720_-\|sugar-transferase	gnl\|CDD\|376775	pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.	6.84461e-106
NZ_CP007512.1\|WP_044585015.1\|4920738_4921440_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	3.70253e-83
NZ_CP007512.1\|WP_044585014.1\|4918737_4919619_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	0
NZ_CP007512.1\|WP_000057889.1\|4935549_4935786_-\|DUF1146-domain-containing-protein	gnl\|CDD\|227173	COG4836, COG4836, Predicted membrane protein [Function unknown].	1.23409e-23
NZ_CP007512.1\|WP_044585021.1\|4937510_4939013_-\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	3.49463e-177
NZ_CP007512.1\|WP_044585018.1\|4929128_4930136_-\|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	9.59871e-31
NZ_CP007512.1\|WP_000544012.1\|4925476_4925749_-\|sporulation-transcriptional-regulator-SpoIIID	gnl\|CDD\|378813	pfam12116, SpoIIID, Stage III sporulation protein D. This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif.	1.17272e-38
NZ_CP007512.1\|WP_044585111.1\|4919859_4920627_-\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	5.34985e-106
NZ_CP007512.1\|WP_000931959.1\|4923452_4923887_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	5.26499e-95
NZ_CP007512.1\|WP_000144443.1\|4927401_4928106_-\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	0.00114363
NZ_CP007512.1\|WP_000457978.1\|4924314_4925316_-\|rod-shape-determining-protein	gnl\|CDD\|237563	PRK13928, PRK13928, rod shape-determining protein Mbl; Provisional.	0
NZ_CP007512.1\|WP_016123874.1\|4930788_4931592_-\|hypothetical-protein	gnl\|CDD\|226297	COG3774, OCH1, Mannosyltransferase OCH1 and related enzymes [Cell envelope biogenesis, outer membrane].	4.51885e-17
NZ_CP007512.1\|WP_044585016.1\|4921429_4922173_-\|capsular-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	1.1226e-84
NZ_CP007512.1\|WP_000170864.1\|4928105_4928948_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.84744e-90
NZ_CP007512.1\|WP_044585017.1\|4922431_4923109_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.24556e-82
NZ_CP007512.1\|WP_000411274.1\|4933449_4934754_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP007512.1\|WP_002005985.1\|4934793_4935504_-\|YwmB-family-TATA-box-binding-protein	gnl\|CDD\|370056	pfam08680, DUF1779, TATA-box binding. TATA-box_bdg is a family of bacterial proteins. YwmB from Bacillus subtilis contains a circularly permuted TATA-box binding protein-like fold. Jian-Xiang Liu, Qi Xie, Jun Lin. Protein Structural Data Mining and Evolutionary Bioinformatic Analysis on Domains of TATA-box Binding Protein-like Fold. Life Science Journal 2014; 11(2): 298-302 (not yet in PubMed 27-02-2014).	5.16446e-34
NZ_CP007512.1\|WP_000367487.1\|4935988_4937509_-\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	3.17734e-150
NZ_CP007512.1\|WP_044585020.1\|4932223_4933243_-\|stage-II-sporulation-protein-D	gnl\|CDD\|274332	TIGR02870, Stage_II_sporulation_protein_D, stage II sporulation protein D. Stage II sporulation protein D (SpoIID) is a protein of the endospore formation program in a number of lineages in the Firmicutes (low-GC Gram-positive bacteria). It is expressed in the mother cell compartment, under control of Sigma-E. SpoIID, along with SpoIIM and SpoIIP, is one of three major proteins involved in engulfment of the forespore by the mother cell. [Cellular processes, Sporulation and germination].	5.70525e-135

>NZ_CP007512.1|WP_000008903.1|4926057_4926192_-|hypothetical-protein
MSFLFVLSTAIILLFVLFTLYYYIAGKKEVPHHQLLEEELEREE
>NZ_CP007512.1|WP_000544012.1|4925476_4925749_-|sporulation-transcriptional-regulator-SpoIIID
MHDYIKERTIKIGKYIVETRKTVRVIAKEFGVSKSTVHKDLTERLPEINPELANEVKEILDYHKSIRHLRGGEATKQKYRKEDVEKPVRQ
>NZ_CP007512.1|WP_000457978.1|4924314_4925316_-|rod-shape-determining-protein
MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNSGKVLAVGEEARSMVGRTPGNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFSKPRILICCPTNITSVEQKAIREAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSIKMAGDKFDMEILNYIKRKYKLLIGERTSEDIKIKVGTVFPGARSEELEIRGRDMVTGLPRTITVCSEEITEALKENAAVIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLLAEELKVPVLIAENPMHCVAVGTGIMLENIDRLPKRALR
>NZ_CP007512.1|WP_000931959.1|4923452_4923887_-|3-hydroxyacyl-ACP-dehydratase-FabZ
MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
>NZ_CP007512.1|WP_044585017.1|4922431_4923109_-|CpsD/CapB-family-tyrosine-protein-kinase
MFGRKKRKPLRQLITHKEPKSRITEQYRNIRTNIEFTSVDNHVRSIIVTSADPGDGKTTTIANLAVVFGQQGKKVLLIGADLRKPTIQNLFAIHSSNGLTNLLSGQAKLMQCIQKTDIENVYLMAAGPIPPNPAELLGSRAMDEALLEAYNMFDIILIDTPPVLAVTDAQILANKCDGIVLVVRSEKTEKDKIVKAKQILDKASGKILGVVLNDKKEEKEQYGYY
>NZ_CP007512.1|WP_044585016.1|4921429_4922173_-|capsular-biosynthesis-protein
MEETISLKELFHILKKRLAMILVIAFGAAIVSAIISFFFMTPIYQSSTQILVNQKKQEGTAIQLGEIQSNIQLTNTYKVIIKSPVILDQVKEKLGLDVTTQDLNEKIEVGNEKDSQVVTVTAIDKDPKLARDIANTTAEVFKGEIAKIMSVDNVTVLSKAEVAESQSPIKPRPMLNVAMAFVVGLMASVGLAFLLEYLDNTVKKEEDVENLLGLPVLGIVARMDEETMNVKSHAPSSRKVRGQTIGS
>NZ_CP007512.1|WP_044585015.1|4920738_4921440_-|CpsD/CapB-family-tyrosine-protein-kinase
MALNLFKKKKNHRQRRQLIAHQQPKSPISEQYRNIRTNIEFAAIDTNLHSLMVTSANPSEGKTTTTANMAVVFAQQGKKVLLIDADMRKPAMHQMFQVDNIFGLTNVLTHSERLEKCVQTTLVDNLHFLACGPIPPNPAELLGSKSMKELLGQAYSMYDLVIFDMPPILAVTDAQIMANVCDASVLVVRSESTEKETAVKAKGLLESAKGKLLGVVLNDREREEGLYYYYGAN
>NZ_CP007512.1|WP_044585111.1|4919859_4920627_-|tyrosine-protein-phosphatase
MIDLHCHILPGIDDGAQTVTDSLAMAQQAVSEGIHTIVATPHHQNGKYINERTSIIHHVKQLNDELQQYNIPLTVLPGQEVRLYGDLLEDYEAGKIVTLNETNKYIFIEFPSNHVPRYAEQLLYELRVKGMIPIIVHPERNAELIERPDKLYNLVNKGVLTQVTAGSLLGKFGKKIKKFSLQLVEHNLTHMVASDAHNTTSRGFHLTGSYELIAKEFGTSVMSDLKENPYLLISGKAIYKEDPEQIRRKKLFGIF
>NZ_CP007512.1|WP_044585014.1|4918737_4919619_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIVVTGKGKRAIEDHFDHSFELEQSLLEKGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYESTQSSVIGVQTVPKNETHRYGIIDPVEQNDRRYQVRQFVEKPAQGTAPSNLAIMGRYVLTSEIFMFLENQQTGAGGEIQLTDAIQRLNEIQRVFAYDFEGTRYDVGEKFGFIKTTIEMALQHEELKEELMEYMNEIVKRENVYV
>NZ_CP007512.1|WP_044585013.1|4918036_4918720_-|sugar-transferase
MNPLKVLDEKVKGNSKELDLSEINARKGYMATKRCMDIIGALCGLIFLSPIFLVVALLIKYEDPKGGVFFKQMRVGKDGKEFYMYKFRSMVTDAEERLQDLLKYNEVSGAMFKIKEDPRITRIGKIIRKTSIDELPQLINVLKGDMSLVGPRPPLPREVKEYTTYDKQRLMVTPGCTGLWQVSGRNSIGFAEMVKLDIYYIENRNLIFDLKIICRTFVVVIKPNDAS
>NZ_CP007512.1|WP_000144443.1|4927401_4928106_-|ABC-transporter-permease
MTFSMRRVSAIFRKEVQDFKTNSQVLLMAFLPIILSFLFSRFGAGKEMLGITTITAFLFVAGFVQSMVIAEEKEKHTLRVLMLSPASSVEVLLGKSILTACLTLGICIVNLFILDQFSGNLLLLGFIFLCGTILFIVIGTMIGLLAASVPQTSIIGMPILMTMYLAVQFEPMVENKVIKTMIGYLPTSHIVKALNSLVGGTGFGSISGHVLNVAVWLIISLFVCLIVYKKKQLD
>NZ_CP007512.1|WP_000170864.1|4928105_4928948_-|ABC-transporter-ATP-binding-protein
MTLAIEMKDVMKSFSGKTALRNVNIEVKQGEIFGFLGPSGSGKTTTVKILTSQLLHSVGTVRVLGKDITGPSSIDYKRIGILTDNSGLYERLSIYDNLLLFCDLYDCKKERIDEVLAQVNLLDDKKTPVKKLSKGMKQRVTLARAILHKPDILFLDEPTSALDPVNVQNIHKILKDLNKEGTTIFLTTHNMDEAETLCNRIAFLCGGEIVALDTPENLRLQYAKDQIQVVLKDKKKETVQKDELGAKRISEWMNKGELLSIHSHEPTLGDIFIEVTGRGL
>NZ_CP007512.1|WP_044585018.1|4929128_4930136_-|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein
MALLELKQLGKANQLPEIELKVKKGQCIVLQCNNHTAKVLHRIIIGEEEASTGNVLFEGEVIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLIGLYESKVSIEEVVQYAGLLDKLNVKIEKLSFSEKRRLHIGRMMIHNPDLIILEEPEQNVDIESTVIIRKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKVEIEQEEAEEVDEEKVVQIIPQMKLERIPAKVNDKIILLDPMEIHFIETQNGVTHIHVREGDFVCALTLSELEARLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
>NZ_CP007512.1|WP_016123874.1|4930788_4931592_-|hypothetical-protein
MNTNIPKIIHYCWFGGKEKPDHIKKYMKTWDGLKDYKIVEWNEKTFDIENNKFVKDAYEGRKWAFVSDYVRLKALYEHGGIYLDTDVELNKNFNDILSNDMFLGFIYDCSIGTAVIGAKPKHPLIKELLDIYEEITFCDNSYIGFTVKRFPNVKLINNNDLFTLFLLNKYKEFKLNNKYQELDGLTIYPKNYFEVQPIFGSKYTVHWCEGSWTGKENGKEVKKYKKLIKSFLASIPFVHFNAVVTHLQHRKKLSKLPFYKYYVEHNK
>NZ_CP007512.1|WP_044585020.1|4932223_4933243_-|stage-II-sporulation-protein-D
MKFSKPLFITVALLIALVIIVPAALVIPFAKAKVGEETASKTPPAIESIPAPGKVDTAVQVAVYREKQKKVETLPVEEYVTGVVASEMNASFEIEALKAQALAARTFVVQRMLNGGKKNNADVTDTVKDQVYKSKDELKKQWGNNYENNLKKIEEAVSKTAGQVLTYDGKPISASFFSTSNGRTENAADYWGNDYPYLKSVDSPWDQASPKFTSEQTFTVADFQKRLGVKVLADGKVGNIKDLTEGKRVKDVAFQGKTLTGKEVREKLDLRSSDFTWKQQGDKIIVTTKGFGHGVGMSQYGANGMAAEGKKYTDIVAHYYKGVEIKTMNDYEGKLMVKK
>NZ_CP007512.1|WP_000411274.1|4933449_4934754_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDSSKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVAATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVNFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>NZ_CP007512.1|WP_002005985.1|4934793_4935504_-|YwmB-family-TATA-box-binding-protein
MKLKLKAILIVALSVVLFLVGYREMKPISDEQKMESMIKALEKNDAKVEKWSWLARETKTISNIHTFQKLLNDVKEKANIQKWEVEQSPDGYKATSYKKLSSYEERVVVTWSKENTKENTFIIFEVSGAKWDPKYVQNMNKIFSEKPIIYTCVQGVLNDKIEGVLQNKTNQVLKDLSARAIEQVEERAFVSVSAYNKKWDDALSTNREKINVQIAIRSTDNKDTIVVGTPIITSEY
>NZ_CP007512.1|WP_000057889.1|4935549_4935786_-|DUF1146-domain-containing-protein
MAQLLGQQALIAIVSHLLFITITWWALQGIHIERLMKSGKVLQTRVLLILITIAIGTSVSNFFLDYLGYSKSLTYLVK
>NZ_CP007512.1|WP_000367487.1|4935988_4937509_-|NADH-quinone-oxidoreductase-subunit-NuoN
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAIVLAIVSLITLYSEPAGDILNGSFVLDGFSKGFKTLLLGASALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFITLFVGLELLSLSSYILVGIRKKSRASNEAAMKYVISGGIGTAITLFGMSYLYGITGSTNIVDMQKVLTGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYEGAATPVTAFLGTISKIAGFLLIIRLFLMVFASVLIQGDMQSLYGHMSIYIAVLASITMIVGNVVALKQYNIKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQNDEENITIFTGLYKRSPFAAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVVSFVYYFRILQQMFFRTGETEERIRLPLNIKVVMSLCAISIVILGIMPMIGYNFFYEYFPLMKDFFFLGNVVQ
>NZ_CP007512.1|WP_044585021.1|4937510_4939013_-|NADH-quinone-oxidoreductase-subunit-M
MNDLLLTFFIFSPLLGILLLVLTPKKELRTVRALGLFGTALPFGIAIVLACTYASGKNLSLFDEKVKWIKFGDFTAVDKRWFSIYYELGIDGLSLVMMVLTALLAMLAAIAAFSIKRNLKAFYMLLLMLEIGMLGVFAAQNLMLFFIFFEITLPPMFLLIGKWGKLSSEKAAYSYLIYNGIGSAILLIVFSILFAKTGTTNIVELKEILRSINAEGALVIPSSLQLSVFIAIMIAFAIKLPVFPLHRWMVNVHIEAHPAVVMLHAGVLLKIGAYGIIRFGKGLFPEYFHDVATLIAILGVINLLYGAFLALIQTDFRKVLAYSSISHMGIVLMGLASLNAPGTQGALFQVVSHGLIAALLFFLLGVIEQRFGTSDITVLGGLAKSVPILSGFFLAGGMASLGLPGMSGFVSEFLAFLGLFQGEPVIAAVGVIGIILTAVYVLRATLQVTFGKKEWEAKSDIHGWEYVPVLLLIFCIIAIGVMPELLGDPLQNTLKTLGVK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007512_2	2.1\|4926403\|31\|NZ_CP007512\|CRISPRCasFinder	4926403-4926433	31	JX238501	Bacillus phage phiAGATE, complete genome	124559-124589	8	0.742
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812210	Flavobacterium phage vB_FspS_hemulen9-1, complete genome	22854-22887	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812215	Flavobacterium phage vB_FspS_lillamy9-4, complete genome	22191-22224	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812216	Flavobacterium phage vB_FspS_lillamy9-5, complete genome	22191-22224	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NC_048835	Flavobacterium phage vB_FspS_lillamy9-1, complete genome	22191-22224	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812213	Flavobacterium phage vB_FspS_lillamy9-2, complete genome	22191-22224	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812230	Flavobacterium phage vB_FspS_sniff9-2, complete genome	21831-21864	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812209	Flavobacterium phage vB_FspS_hemulen6-2, complete genome	22983-23016	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812218	Flavobacterium phage vB_FspS_lillamy9-7, complete genome	21454-21487	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812233	Flavobacterium phage vB_FspS_snork9-1, complete genome	22007-22040	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812219	Flavobacterium phage vB_FspS_morran9-1, complete genome	22308-22341	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812217	Flavobacterium phage vB_FspS_lillamy9-6, complete genome	21930-21963	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NC_048840	Flavobacterium phage vB_FspS_snork6-1, complete genome	22137-22170	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NC_048839	Flavobacterium phage vB_FspS_sniff9-1, complete genome	22057-22090	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NC_048842	Flavobacterium phage vB_FspS_stinky9-1, complete genome	21673-21706	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812232	Flavobacterium phage vB_FspS_snork6-2, complete genome	21655-21688	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	MN812208	Flavobacterium phage vB_FspS_hemulen6-1, complete genome	22983-23016	9	0.735
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47181-47214	11	0.676
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47565-47598	11	0.676
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47949-47982	11	0.676
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48333-48366	11	0.676
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48717-48750	11	0.676
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49101-49134	11	0.676
NZ_CP007512_2	2.2\|4926457\|34\|NZ_CP007512\|CRISPRCasFinder	4926457-4926490	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49485-49518	11	0.676

1. spacer 2.1|4926403|31|NZ_CP007512|CRISPRCasFinder matches to JX238501 (Bacillus phage phiAGATE, complete genome) position: , mismatch: 8, identity: 0.742

ttcttcttttttgtcactagttgaaccgctt	CRISPR spacer
ctaaccttttttgccactagttaaaccgccc	Protospacer
.*  .********.********.******..

2. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812210 (Flavobacterium phage vB_FspS_hemulen9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

3. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812215 (Flavobacterium phage vB_FspS_lillamy9-4, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

4. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812216 (Flavobacterium phage vB_FspS_lillamy9-5, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

5. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NC_048835 (Flavobacterium phage vB_FspS_lillamy9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

6. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812213 (Flavobacterium phage vB_FspS_lillamy9-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

7. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812230 (Flavobacterium phage vB_FspS_sniff9-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

8. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812209 (Flavobacterium phage vB_FspS_hemulen6-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

9. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812218 (Flavobacterium phage vB_FspS_lillamy9-7, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

10. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812233 (Flavobacterium phage vB_FspS_snork9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

11. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812219 (Flavobacterium phage vB_FspS_morran9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

12. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812217 (Flavobacterium phage vB_FspS_lillamy9-6, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

13. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NC_048840 (Flavobacterium phage vB_FspS_snork6-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

14. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NC_048839 (Flavobacterium phage vB_FspS_sniff9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

15. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NC_048842 (Flavobacterium phage vB_FspS_stinky9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

16. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812232 (Flavobacterium phage vB_FspS_snork6-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

17. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to MN812208 (Flavobacterium phage vB_FspS_hemulen6-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

18. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

19. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

20. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

21. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

22. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

23. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

24. spacer 2.2|4926457|34|NZ_CP007512|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

102164 : 110113

uncultured_virus(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000917311.1\|102164_102449_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	1.2e-20	54.8
WP_001029993.1\|102487_104122_+	chaperonin GroEL	A0A219YK78	uncultured_virus	1.5e-157	58.0
WP_164514075.1\|104525_106067_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.2e-21	31.7
WP_000833096.1\|106452_107778_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	4.1e-44	29.4
WP_000929884.1\|107922_108624_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.3e-40	36.9
WP_000719212.1\|108607_110113_+	aminopeptidase AmpS	W8CYF6	Bacillus_phage	1.1e-32	30.7

DBSCAN-SWA_2

154691 : 163067

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000625682.1\|154691_155999_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.9e-21	25.3
WP_001170544.1\|156087_156807_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.0e-49	44.3
WP_000278823.1\|156799_157054_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666787.1\|157050_157734_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_000055565.1\|157717_159937_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	2.0e-163	41.2
WP_000879025.1\|159921_161337_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.3e-55	35.4
WP_001262439.1\|161442_162483_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.2e-67	45.9
WP_000088596.1\|162479_163067_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.5e-27	36.4

DBSCAN-SWA_3

492632 : 500639

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_113710808.1\|492632_493607_-	YafY family transcriptional regulator	A0A1B0RXM1	Streptococcus_phage	2.7e-16	28.9
WP_000085764.1\|493682_494204_+	dihydrofolate reductase	NA	NA	NA	NA
WP_044584134.1\|494216_495608_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.5e-36	31.8
WP_000565484.1\|495619_496297_-	response regulator transcription factor	W8CYM9	Bacillus_phage	8.3e-33	36.1
WP_030023104.1\|496472_497720_+	hypothetical protein	NA	NA	NA	NA
WP_000277062.1\|497853_498384_+	DUF4352 domain-containing protein	A0A0S2MVG4	Bacillus_phage	5.5e-16	33.7
WP_000831286.1\|498396_498741_+	DUF4064 domain-containing protein	A0A0S2MVJ2	Bacillus_phage	8.5e-42	78.1
WP_025966741.1\|499187_500639_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	3.7e-139	54.0

DBSCAN-SWA_4

1495001 : 1511806

Brevibacillus_phage(100.0%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000465973.1\|1495001_1495454_+	hypothetical protein	A0A0K2CP30	Brevibacillus_phage	8.9e-23	43.0
WP_000077127.1\|1495453_1496542_+	hypothetical protein	A0A0K2CNX7	Brevibacillus_phage	2.7e-94	55.6
WP_016098062.1\|1496774_1497245_+	hypothetical protein	A0A0K2CPC8	Brevibacillus_phage	3.9e-37	55.4
WP_044584302.1\|1497331_1497574_+	hypothetical protein	A0A0K2CP74	Brevibacillus_phage	2.1e-18	55.0
WP_044584303.1\|1497646_1502998_+\|tail	phage tail tape measure protein	A0A0K2CPN3	Brevibacillus_phage	1.3e-141	26.4
WP_000068593.1\|1503056_1503674_+	S-layer homology domain-containing protein	A0A0K2CPJ2	Brevibacillus_phage	1.4e-71	60.7
WP_044584304.1\|1503676_1504750_+	hypothetical protein	A0A0K2CP35	Brevibacillus_phage	4.1e-74	40.3
WP_044584305.1\|1504763_1507955_+	M23 family metallopeptidase	A0A0K2CNY2	Brevibacillus_phage	3.7e-06	50.0
WP_000057631.1\|1508033_1508750_+	hypothetical protein	NA	NA	NA	NA
WP_000007798.1\|1508764_1509205_+	hypothetical protein	NA	NA	NA	NA
WP_044584306.1\|1509220_1511806_+	hypothetical protein	A0A0K2CPJ7	Brevibacillus_phage	2.1e-31	43.5

DBSCAN-SWA_5

1524734 : 1539296

Brevibacillus_phage(55.56%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044584311.1\|1524734_1525856_+	hypothetical protein	A0A0K2CPP1	Brevibacillus_phage	1.6e-65	36.7
WP_000537240.1\|1525867_1526599_+	hypothetical protein	NA	NA	NA	NA
WP_044584312.1\|1526677_1527121_+	hypothetical protein	A0A0K2CPK2	Brevibacillus_phage	3.9e-23	39.8
WP_044584313.1\|1527196_1527688_+	hypothetical protein	A0A0K2CNZ3	Brevibacillus_phage	2.4e-37	55.2
WP_044584314.1\|1527728_1528340_+	hypothetical protein	A0A127AW14	Bacillus_phage	7.5e-49	52.1
WP_044584315.1\|1528324_1531216_+	hypothetical protein	A0A127AW61	Bacillus_phage	8.3e-13	33.0
WP_044584316.1\|1531258_1535614_+	DNRLRE domain-containing protein	A0A0K2CP88	Brevibacillus_phage	3.2e-32	24.3
WP_001125914.1\|1536184_1536553_+	hypothetical protein	NA	NA	NA	NA
WP_044584317.1\|1536552_1536930_+	hypothetical protein	NA	NA	NA	NA
WP_044584318.1\|1537128_1538136_+	N-acetylmuramoyl-L-alanine amidase	A0A127AWA8	Bacillus_phage	1.3e-10	48.4
WP_044584319.1\|1538152_1538452_+	hypothetical protein	A0A0K2CPL0	Brevibacillus_phage	5.0e-22	59.3
WP_044584320.1\|1538471_1539296_+	hypothetical protein	A7KV11	Bacillus_phage	1.2e-78	68.9

DBSCAN-SWA_6

1547418 : 1556804

Brevibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044584328.1\|1547418_1548126_-	DNA polymerase I	A0A0K2CNW2	Brevibacillus_phage	9.5e-64	53.1
WP_000781409.1\|1548294_1548699_-	hypothetical protein	NA	NA	NA	NA
WP_044584329.1\|1549322_1550717_-	DNA polymerase I	A0A0K2CP19	Brevibacillus_phage	5.4e-103	45.9
WP_044584330.1\|1550803_1551463_-	hypothetical protein	A0A0K2CPH8	Brevibacillus_phage	2.3e-56	56.5
WP_001090550.1\|1551925_1552483_-	sigma-70 family RNA polymerase sigma factor	A0A0K2CPD2	Brevibacillus_phage	2.4e-25	41.1
WP_044584331.1\|1552510_1553587_-	toprim domain-containing protein	A0A0K2CNW6	Brevibacillus_phage	2.2e-104	54.3
WP_044584332.1\|1553611_1554904_-	DNA helicase	A0A0K2CP24	Brevibacillus_phage	2.0e-139	57.7
WP_044584333.1\|1555383_1556154_-	ATP-binding protein	A0A0K2CNX1	Brevibacillus_phage	1.3e-61	48.0
WP_042972363.1\|1556213_1556804_-	helix-turn-helix domain-containing protein	A0A0K2CNS5	Brevibacillus_phage	1.7e-26	44.3

DBSCAN-SWA_7

1719831 : 1727978

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000755525.1\|1719831_1721112_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	3.4e-11	31.5
WP_001194306.1\|1721211_1721976_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_000453865.1\|1722216_1723977_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.1e-273	98.0
WP_000612414.1\|1724062_1724740_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-122	99.1
WP_001231615.1\|1724736_1725810_+	sensor histidine kinase	W8CYF6	Bacillus_phage	5.1e-186	97.5
WP_000818985.1\|1726098_1726818_+	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0
WP_001258503.1\|1727105_1727978_+	aminoglycoside 6-adenylyltransferase	A0A1X9I6F2	Streptococcus_phage	5.6e-66	45.5

DBSCAN-SWA_8

2364810 : 2370047

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001139345.1\|2364810_2365026_-	spore germination protein	A0A2H4J3A3	uncultured_Caudovirales_phage	3.4e-25	83.8
WP_114556335.1\|2365262_2365394_+	DUF3983 domain-containing protein	A0A1B1P7V8	Bacillus_phage	1.1e-10	76.7
WP_000097509.1\|2365758_2366559_+	C1 family peptidase	A0A2K9L1Z4	Tupanvirus	1.0e-37	37.2
WP_002005147.1\|2366578_2366791_+	hypothetical protein	NA	NA	NA	NA
WP_002005146.1\|2366855_2367056_+	N-acetylmuramoyl-L-alanine amidase	D2XR33	Bacillus_phage	1.3e-15	90.9
WP_000654547.1\|2367193_2368075_-	serine/threonine protein kinase	NA	NA	NA	NA
WP_000372690.1\|2368202_2368712_+	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	1.4e-16	36.0
WP_000411454.1\|2368829_2369360_+	hypothetical protein	NA	NA	NA	NA
WP_044584503.1\|2369372_2370047_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.6e-28	30.7

DBSCAN-SWA_9

3410184 : 3419317

Bacillus_phage(63.64%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044584779.1\|3410184_3411243_-	N-acetylmuramoyl-L-alanine amidase	A0A1B0T6C8	Bacillus_phage	3.3e-153	73.0
WP_000570184.1\|3411239_3411479_-	hypothetical protein	A0A0A7AR38	Bacillus_phage	5.0e-25	73.4
WP_000377824.1\|3411478_3411715_-	hemolysin XhlA family protein	A0A288WG97	Bacillus_phage	3.9e-14	88.6
WP_000405936.1\|3411905_3412790_-	N-acetylmuramoyl-L-alanine amidase	A0A0S2MVR5	Bacillus_phage	8.0e-76	51.0
WP_044584780.1\|3413062_3413887_-	M23 family metallopeptidase	A0A218KCJ1	Bacillus_phage	1.9e-26	42.7
WP_044585099.1\|3414028_3415000_-	lysozyme family protein	A0A223LKM8	Bacillus_phage	5.4e-33	42.3
WP_000464424.1\|3415238_3415625_-	DUF1492 domain-containing protein	A0A288WG73	Bacillus_phage	2.2e-46	70.6
WP_000900735.1\|3415599_3415764_-	hypothetical protein	NA	NA	NA	NA
WP_044584781.1\|3417073_3417268_-	hypothetical protein	A0A2H4J4V8	uncultured_Caudovirales_phage	4.5e-16	71.0
WP_001249544.1\|3417279_3418038_-	ORF6C domain-containing protein	A0A2H4JBC7	uncultured_Caudovirales_phage	1.6e-96	69.4
WP_000283431.1\|3418240_3418453_-	hypothetical protein	A6M975	Geobacillus_virus	1.6e-11	63.0
WP_044584782.1\|3418657_3419317_+	helix-turn-helix domain-containing protein	A0A2H4J441	uncultured_Caudovirales_phage	2.3e-35	41.0

DBSCAN-SWA_10

4237987 : 4245673

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000221067.1\|4237987_4238911_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.5e-45	43.5
WP_000609141.1\|4239036_4239972_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.2e-21	24.8
WP_000018029.1\|4239973_4240666_-	response regulator transcription factor	B5LWA6	Feldmannia_species_virus	1.4e-06	28.8
WP_001293578.1\|4240834_4241008_+	hypothetical protein	NA	NA	NA	NA
WP_001014310.1\|4241008_4241203_+	YwbE family protein	NA	NA	NA	NA
WP_001255971.1\|4241241_4242441_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	1.6e-71	41.2
WP_000587818.1\|4242736_4243060_+	heme oxygenase	NA	NA	NA	NA
WP_044584888.1\|4243132_4243897_-	class B sortase	NA	NA	NA	NA
WP_000403761.1\|4243929_4244700_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	7.6e-14	28.6
WP_001036848.1\|4244689_4245673_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	27.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP007513

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

174574 : 215505

Bacillus_phage(70.0%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044585188.1\|174574_175696_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	1.8e-165	77.7
WP_001293562.1\|175863_176031_+	hypothetical protein	NA	NA	NA	NA
WP_044585189.1\|176543_176768_+	hypothetical protein	NA	NA	NA	NA
WP_016090324.1\|176968_177175_+	hypothetical protein	NA	NA	NA	NA
WP_044585190.1\|177272_177587_+	hypothetical protein	NA	NA	NA	NA
WP_044585191.1\|178590_179484_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_000516003.1\|181017_181536_-	DUF4352 domain-containing protein	A0A1B1P898	Bacillus_phage	4.9e-49	77.0
WP_044585192.1\|181777_182437_-	class D sortase	NA	NA	NA	NA
WP_000734536.1\|182493_183081_-	excalibur calcium-binding domain-containing protein	NA	NA	NA	NA
WP_001253140.1\|184447_184633_+	hypothetical protein	NA	NA	NA	NA
WP_044585193.1\|186208_187522_+	DUF3854 domain-containing protein	NA	NA	NA	NA
WP_044585194.1\|187652_188564_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_167319648.1\|188718_188889_+	hypothetical protein	NA	NA	NA	NA
WP_003308572.1\|189054_189423_+	hypothetical protein	NA	NA	NA	NA
WP_001233530.1\|189489_189840_+	PrgI family protein	NA	NA	NA	NA
WP_044585195.1\|189840_190749_+	hypothetical protein	NA	NA	NA	NA
WP_044585196.1\|190751_192851_+	DUF87 domain-containing protein	NA	NA	NA	NA
WP_044585197.1\|192881_196916_+	hypothetical protein	NA	NA	NA	NA
WP_044585198.1\|199136_199712_+	hypothetical protein	NA	NA	NA	NA
WP_044585199.1\|199875_200271_+	hypothetical protein	NA	NA	NA	NA
WP_044585200.1\|200255_200555_+	DUF2325 domain-containing protein	NA	NA	NA	NA
WP_044585201.1\|200629_200995_+	hypothetical protein	NA	NA	NA	NA
WP_044585202.1\|201553_201976_+	hypothetical protein	A0A1B1P7B4	Bacillus_phage	3.8e-60	77.1
WP_044585392.1\|202059_202743_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_044585203.1\|202855_203380_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_044585204.1\|203609_204755_-	DUF418 domain-containing protein	NA	NA	NA	NA
WP_044585205.1\|204794_205277_-	thioredoxin family protein	NA	NA	NA	NA
WP_000648342.1\|205911_206190_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	7.1e-15	65.6
WP_044585206.1\|206783_208013_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_119782055.1\|208247_208418_-	hypothetical protein	NA	NA	NA	NA
WP_016078507.1\|208853_209972_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	2.6e-172	81.2
WP_044585207.1\|210511_210886_-	hypothetical protein	D2XQ01	Bacillus_virus	2.6e-28	50.4
WP_044585208.1\|210933_211275_-	YolD-like family protein	A0A1Q1PW34	Staphylococcus_phage	1.2e-08	37.3
WP_000272587.1\|211271_212537_-	Y-family DNA polymerase	O64031	Bacillus_phage	1.9e-102	46.7
WP_130067921.1\|213393_213534_-\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_001281108.1\|213665_214361_+	VanA-type vancomycin resistance DNA-binding response regulator VanR	W8CYM9	Bacillus_phage	1.3e-36	37.7
WP_044585209.1\|214350_215505_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.2e-17	24.8

DBSCAN-SWA_2

224877 : 280180

Bacillus_phage(41.67%)

transposase,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000762752.1\|224877_225276_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	3.1e-51	68.9
WP_044585212.1\|225287_226400_+	helix-turn-helix domain-containing protein	A0A288TXV8	Enterococcus_phage	4.4e-79	47.8
WP_001988281.1\|226524_226665_+	hypothetical protein	NA	NA	NA	NA
WP_044585213.1\|228169_228694_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_044585214.1\|229159_230392_+	cytochrome P450	A0A2I2L481	Orpheovirus	7.9e-05	25.4
WP_165851690.1\|230871_231009_+	hypothetical protein	NA	NA	NA	NA
WP_080478555.1\|231674_231800_+	sporulation protein	NA	NA	NA	NA
WP_044585215.1\|231894_232998_-\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_001988301.1\|233151_234288_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_000393190.1\|234312_235371_+\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_000093658.1\|235372_235798_+	hypothetical protein	NA	NA	NA	NA
WP_044585216.1\|235878_236238_+	hypothetical protein	NA	NA	NA	NA
WP_000686383.1\|236702_237893_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_044585217.1\|237896_238850_-	NAD-dependent epimerase/dehydratase family protein	A0A2K9L0I7	Tupanvirus	8.7e-36	33.0
WP_044585218.1\|238846_240136_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.1e-76	36.1
WP_000591181.1\|240333_241155_+	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	1.6e-54	46.0
WP_133300474.1\|243710_243893_+	hypothetical protein	NA	NA	NA	NA
WP_044585220.1\|244347_244944_+	ABC transporter permease	NA	NA	NA	NA
WP_000648354.1\|245910_246189_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	1.1e-12	59.0
WP_000978065.1\|246613_246853_-	hypothetical protein	NA	NA	NA	NA
WP_044585221.1\|248571_249858_+	amino acid permease	NA	NA	NA	NA
WP_000654819.1\|249841_250438_+	methylphosphotriester-DNA--protein-cysteine methyltransferase family protein	V9LZQ4	Vibrio_phage	1.2e-06	32.0
WP_001245414.1\|250702_251176_+	DUF1203 domain-containing protein	NA	NA	NA	NA
WP_044585222.1\|252428_252989_-\|coat	spore coat protein	NA	NA	NA	NA
WP_001127871.1\|253627_253798_+	DUF4083 family protein	NA	NA	NA	NA
WP_044585223.1\|253853_254240_+	DUF5412 domain-containing protein	NA	NA	NA	NA
WP_044585394.1\|254412_254685_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	6.5e-21	63.3
WP_044585224.1\|254958_256428_-	glutamate decarboxylase	NA	NA	NA	NA
WP_033685851.1\|257759_258164_+	DUF3221 domain-containing protein	NA	NA	NA	NA
WP_033689769.1\|259821_260334_+	DNA-binding protein	NA	NA	NA	NA
WP_001033550.1\|260555_261425_+	putative phage abortive infection protein	NA	NA	NA	NA
WP_000394778.1\|261589_261745_+	hypothetical protein	NA	NA	NA	NA
WP_044585225.1\|261949_262771_+	hypothetical protein	NA	NA	NA	NA
WP_170924512.1\|262970_263408_+	hypothetical protein	NA	NA	NA	NA
WP_044585226.1\|263619_264012_-	DUF4878 domain-containing protein	NA	NA	NA	NA
WP_044585227.1\|265172_266819_-	S-layer homology domain-containing protein	NA	NA	NA	NA
WP_044585229.1\|268453_270067_+	S-layer homology domain-containing protein	A0A1J0MS59	Bacillus_phage	9.5e-43	52.6
WP_187388508.1\|270694_271090_+	hypothetical protein	NA	NA	NA	NA
WP_050043500.1\|271276_272194_-	hypothetical protein	NA	NA	NA	NA
WP_044585231.1\|273248_273650_+	BlaI/MecI/CopY family transcriptional regulator	NA	NA	NA	NA
WP_044585232.1\|273649_275572_+	beta-lactam sensor/signal transducer	NA	NA	NA	NA
WP_187388509.1\|276677_277796_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	4.0e-173	81.2
WP_000738326.1\|278491_279034_+	hypothetical protein	NA	NA	NA	NA
WP_000762752.1\|279781_280180_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	3.1e-51	68.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007512

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP007513

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection