CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007571	Streptococcus agalactiae strain GBS2-NM chromosome, complete genome	2 crisprs	RT,cas3,DinG,cas9,cas1,cas2,csn2,csm6,DEDDh,csa3	0	4	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007571_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007571_1

1003794-1004018

TypeII

II-A

Consensus_repeat	Method
GGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRISPRCasFinder
GGTTTTAGAGCTGTGCTGTTTCGAATG	CRT

3 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP007571_1

>merge|NZ_CP007571|1|1003794-1004018|CRISPRCasFinder,CRT
GGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTGCAATGTTATTTGATGATGGAACAACATGGTTTTAGAGCTGTGCTGTTTCGAATGATTCCAAAACAATACAATAGTCGCACAAACAGCGAACAGTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTTTAATATCGTCTATATAGATTCCTGGACGGTTTTAGAGCTGCGCGGTTATTATGC

>NZ_CP007571|1|1|1003794-1003962|CRISPRCasFinder
GGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGCAATGTTATTTGATGATGGAACAACAT
GGTTTTAGAGCTGTGCTGTTTCGAATGATTCCAAAAC	AATACAATAGTCGCACAAACAGCGAACAG
TGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>NZ_CP007571|1|1|1003794-1004018|CRT
GGTTTTAGAGCTGTGCTGTTTCGAATG	GTTCCAAAACTGCAATGTTATTTGATGATGGAACAACAT
GGTTTTAGAGCTGTGCTGTTTCGAATG	ATTCCAAAACAATACAATAGTCGCACAAACAGCGAACAG
TGTTTTAGAGCTGTGCTGTTTCGAATG	GTTCCAAAACTTTAATATCGTCTATATAGATTCCTGGAC
GGTTTTAGAGCTGCGCGGTTATTATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007571.1\|WP_000665410.1\|1011063_1011498_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP007571.1\|WP_000914659.1\|994056_995187_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_CP007571.1\|WP_000122194.1\|1002700_1003042_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP007571.1\|WP_000323544.1\|995928_996699_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP007571.1\|WP_000146568.1\|1015664_1016303_-\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_CP007571.1\|WP_000653355.1\|996688_997345_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_CP007571.1\|WP_000929489.1\|1001834_1002704_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP007571.1\|WP_000523795.1\|995190_995928_+\|acyl-ACP-thioesterase	unknown	unknown	gnl\|CDD\|366738
NZ_CP007571.1\|WP_001040096.1\|997720_1001833_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP007571.1\|WP_000438313.1\|1004568_1004985_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_CP007571.1\|WP_001056394.1\|1018550_1019162_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP007571.1\|WP_000168908.1\|1011650_1014443_+\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NZ_CP007571.1\|WP_000180011.1\|1009931_1010591_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224336
NZ_CP007571.1\|WP_001241816.1\|993583_993964_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131381
NZ_CP007571.1\|WP_000590703.1\|1003028_1003694_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	pfam09711_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP007571.1\|WP_001019128.1\|1005120_1006953_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP007571.1\|WP_000678289.1\|1007198_1009832_+\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|380193
NZ_CP007571.1\|WP_000159234.1\|993187_993559_+\|YbgA-family-protein	unknown	unknown	gnl\|CDD\|377982
NZ_CP007571.1\|WP_000065324.1\|1014442_1015546_+\|DUF2974-domain-containing-protein	unknown	unknown	gnl\|CDD\|371412
NZ_CP007571.1\|WP_000621143.1\|1010599_1011064_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181

Protein	Function_ID	Function_description	E-value
NZ_CP007571.1\|WP_000665410.1\|1011063_1011498_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	6.40832e-86
NZ_CP007571.1\|WP_000914659.1\|994056_995187_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_CP007571.1\|WP_000122194.1\|1002700_1003042_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.38084e-52
NZ_CP007571.1\|WP_000323544.1\|995928_996699_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19143e-132
NZ_CP007571.1\|WP_000146568.1\|1015664_1016303_-\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	2.15538e-71
NZ_CP007571.1\|WP_000653355.1\|996688_997345_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	8.37758e-51
NZ_CP007571.1\|WP_000929489.1\|1001834_1002704_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	2.54315e-139
NZ_CP007571.1\|WP_000523795.1\|995190_995928_+\|acyl-ACP-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	3.68196e-111
NZ_CP007571.1\|WP_001040096.1\|997720_1001833_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP007571.1\|WP_000438313.1\|1004568_1004985_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	6.25805e-79
NZ_CP007571.1\|WP_001056394.1\|1018550_1019162_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	6.1265e-31
NZ_CP007571.1\|WP_000168908.1\|1011650_1014443_+\|cation-transporting-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NZ_CP007571.1\|WP_000180011.1\|1009931_1010591_+\|HD-domain-containing-protein	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	2.46285e-32
NZ_CP007571.1\|WP_001241816.1\|993583_993964_+\|hypothetical-protein	gnl\|CDD\|131381	TIGR02328, TIGR02328, conserved hypothetical protein. Members of this protein are found in a small number of taxonomically well separated species, yet are strongly conserved, suggesting lateral gene transfer. Members are found in Treponema denticola, Clostridium acetobutylicum, and several of the Firmicutes. The function of this protein is unknown. [Hypothetical proteins, Conserved].	6.45558e-80
NZ_CP007571.1\|WP_000590703.1\|1003028_1003694_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	4.68487e-122
NZ_CP007571.1\|WP_001019128.1\|1005120_1006953_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP007571.1\|WP_000678289.1\|1007198_1009832_+\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|380193	NF033189, internalin_A, class 1 internalin InlA. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface or secreted proteins with an N-terminal signal peptide, leucine-rich repeats, and usually a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin A (InlA), a class 1 (LPXTG-type) internalin.	5.90067e-22
NZ_CP007571.1\|WP_000159234.1\|993187_993559_+\|YbgA-family-protein	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	6.08694e-28
NZ_CP007571.1\|WP_000065324.1\|1014442_1015546_+\|DUF2974-domain-containing-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	2.245e-105
NZ_CP007571.1\|WP_000621143.1\|1010599_1011064_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.29827e-18

>NZ_CP007571.1|WP_000590703.1|1003028_1003694_+|type-II-A-CRISPR-associated-protein-Csn2
MIKINFPILDEPLVLSNATILTIEDVSVYSSLVKHFYQYDVDEHLKLFDDKQKSLKAAELMLVTDILGYDVNSAPILKLIHGDLENQFNEKPEVKSMVEKLAATITELIAFECLENELDLEYDEITILELIKALGVKIETQSDTIFEKCFEIIQVYHYLTKKNLLVFVNSGAYLTKDEVIKLCEYINLMQKSVLFLEPRRLYDLPQYVIDKDYFLIGENMV
>NZ_CP007571.1|WP_000122194.1|1002700_1003042_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNTANNAMIGRLKVNNPKKGNITLLTVTEKQFARMVYLHGERNTSVANSDSRLVFLGDSYDQD
>NZ_CP007571.1|WP_000929489.1|1001834_1002704_+|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDSYQTEMIHLSEIDILIMETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARHDSSLQLSRQMSWIEDVKADVWTSIIAQKILNQSFYLGECSFFEKSQSIMNLYHDLEPFDPSNREGHAARIYFNTLFGNDFSREQDNPINAGLDYGYSLLLSMFAREVVKCGCMTQFGLKHANQFNQFNLASDIMEPFRPIVDRIIYENRQSDFVKMKRELFSMFSETYSYNGKEMYLSNIVSDYTKKVIKSLNSDGNGIPEFRI
>NZ_CP007571.1|WP_001040096.1|997720_1001833_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNKPYSIGLDIGTNSVGWSIITDDYKVPAKKMRVLGNTDKEYIKKNLIGALLFDGGNTAADRRLKRTARRRYTRRRNRILYLQEIFAEEMSKVDDSFFHRLEDSFLVEEDKRGSKYPIFATMQEEKYYHEKFPTIYHLRKELADKKEKADLRLIYLALAHIIKFRGHFLIEDDRFDVRNTDIQKQYQAFLEIFDTTFENNDLLSQNVDVEAILTDKISKSAKKDRILARYPNQKSTGIFAEFLKLIVGNQADFKKHFNLEDKTPLQFAKDSYDEDLENLLGQIGDEFADLFSAAKKLYDSVLLSGILTVTDLSTKAPLSASMIQRYDEHREDLKQLKQFVKASLPEKYQEIFADSSKDGYAGYIEGKTNQEAFYKYLSKLLTKQEGSEYLLEKIKNEDFLRKQRTFDNGSIPHQVHLTELRAIIRRQSEYYPFLKENLDRIEKILTFRIPYYVGPLAREKSDFAWMTRKTDDSIRPWNFEDLVDKEKSAEAFIHRMTNNDLYLPEEKVLPKHSLIYEKFTVYNELTKVRFLAEGFKDFQFLNRKQKETIFNSLFKEKRKVTEKDIISFLNKVDGYEGIAIKGIEKQFNASLSTYHDLKKILGKDFLDNTDNELILEDIVQTLTLFEDREMIRKRLDIYKDFFTESQLKKLYRRHYTGWGRLSAKLINGIRNKENQKTILDYLIDDGSANRNFMQLIKDAGLSFKPIIDKARTGSHLDNLKEVVGELAGSPAIKKGILQSLKIVDELVKVMGYEPEQIVVEMARENQTTAKGLSRSRQRLTTLRESLANLKSNILEEKKPKYVKDQVENHHLSDDRLFLYYLQNGKDMYTDDELDIDNLSQYDIDHIIPQAFIKDDSIDNRVLVSSAKNRGKSDDVPSLEIVKDCKVFWKKLLDAKLMSQRKYDNLTKAERGGLTSDDKARFIQRQLVETRQITKHVARILDERFNNELDSKGRRIRKVKIVTLKSNLVSNFRKEFGFYKIREVNNYHHAHDAYLNAVVAKAILTKYPQLEPEFVYGDYPKYNSYKTRKSATEKLFFYSNIMNFFKTKVTLADGTVVVKDDIEVNNDTGEIVWDKKKHFATVRKVLSYPQVNIVKKTEVQTGGFSKESILAHGNSDKLIPRKTKDIYLDPKKYGGFDSPIVAYSVLVVADIKKGKAQKLKTVTELLGITIMERSRFEKNPSAFLESKGYLNIRTDKLIILPKYSLFELENGRRRLLASAGELQKGNELALPTQYMKFLYLASRYNELKGKPEEIEQKQEFVVQHVSYFDDILQIINDFSNRVILADANLEKINKLYQDNKENIPVDELANNIINLFTFTSLGAPAAFKFFDKIVDRKRYTSTKEVLNSTLIHQSITGLYETRIDLGKLGEG
>NZ_CP007571.1|WP_000653355.1|996688_997345_+|TIGR01906-family-membrane-protein
MKDKLLVVLTWIWIISLATLATIYIAWLIYPIEIQFLKLEKVVYLKAETIYYNFNKLMIYLTHPFISDLNMPSFPSSEDGLKHFADVKYLFTLAHGLFVILTFPVIYFLRHGWKQKSIFLYEGFFKIAIMLPIFIVVCAFLLGFDQFFTLFHEVLFPGDSTWQFNPLTDPVIWILPETFFLHCFIIFLLIYETITIILLIIGRKHLKLRKYKNKMQAL
>NZ_CP007571.1|WP_000323544.1|995928_996699_+|TIGR01457-family-HAD-type-hydrolase
MAYKGYLIDLDGTIYKGKSRIPAGERFIERLQEKGIPYMLVTNNTTRTPESVQEMLRGFNVETPLETIYTATMATVDYMNDMNRGKTAYVIGEEGLKKAIADAGYVEDTKNPAYVVVGLDWNVTYDKLATATLAIQNGALFIGTNPDLNIPTERGLLPGAGSLNALLEAATRIKPVFIGKPNAIIMNKALEILNIPRNQAVMVGDNYLTDIMAGINNDIDTLLVTTGFTTVEEVPDLPIQPSYVLASLDEWTFNEG
>NZ_CP007571.1|WP_000523795.1|995190_995928_+|acyl-ACP-thioesterase
MGLLYRETYEVPFYESDTNHYMKLPQLLALALQISAKQSLKLGIGDDIVFKRYGLVWVVTDYIIDIERLPKHAEKIVIETEAKAHNKLLCYRYFYIYGEDGQKIITISSAFVLMDFKTRKIHPVLDDITSIYQSQRIKKVIRGPKYHPIGDSKVKQYHVRYFDLDMNGHVNNSKYLEWMYDVLDLDFLSSHIPKKIDLKYIKEIQYGTDIKSHWYQDGLVTRHDIIGGDAIHAQARIEWQEKKED
>NZ_CP007571.1|WP_000914659.1|994056_995187_+|oxygen-independent-coproporphyrinogen-III-oxidase
MLKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLQALIREFRSYDITELRTLYIGGGTPTSISAVQLDYLLTELIRDLNLNTLEEFTIEANPGDLTVDKIEVLQKSAVNRVSLGVQTFNDKHLKRIGRSHNEAQIYSTIDALKTAGFQNISIDLIYALPGQTMDDVRSNVAKALSLNIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEMFEYIISEMERNGFEHYEISNFTKPGFESRHNLMYWENVEYYGVGAGASGYLDGIRYRNRGPIQHYLKGVSEGNARLSEEVLSKNEMMEEELFLGLRKKEGVSIGKFEQKFGTSFEKRYGQIVQELQSDGLLKENNGFIQMTKKGLFLGDTVAEKFIVE
>NZ_CP007571.1|WP_001241816.1|993583_993964_+|hypothetical-protein
MRLWHQDIIELLPRQQLLGQHRECCALRGNGWGRKHETVDYVFRYSPYRLFAYHQLVMEEMMERGYRVSKEWLIAEYRGMKCPRYDTLNPVDLETPIYPEHNQDYLQECLWNLKAKGIDLPINKIK
>NZ_CP007571.1|WP_000159234.1|993187_993559_+|YbgA-family-protein
MTKEAELLWAKHKYLVLSKSQKIYLDIRQTLKSPNCTVLDVQSLIDQAVLLEESPSQVTNAYMHIWGYFKNKAERQEKEEFLTLLEKYRKTGYQRRKLLAFLKQLLAKYPNSYLQNSSIFEEE
>NZ_CP007571.1|WP_000438313.1|1004568_1004985_+|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVKRGFIGEVISRIERRGFSIDRLEVRHADADILKRHYAELTDRPFFPTLVDYMTSGPVIIGVISGEEVISTWRTMMGSTNPKDALPGTIRGDFAQAPSPNQATCNIVHGSDSPESATREIAIWFNN
>NZ_CP007571.1|WP_001019128.1|1005120_1006953_+|elongation-factor-4
MNIEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRAEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGEVDAPLQALIFDSVYDAYRGVILQVRIINGMVKPGDKIQMMSNGKTFDVTEVGIFNPKAVGRDFLATGDVGYIAASIKTVADTRVGDTITLANNPAIEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSEFPDPTRVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDDKK
>NZ_CP007571.1|WP_000678289.1|1007198_1009832_+|pneumococcal-type-histidine-triad-protein
MKGQKIIALAGLVLSCHFALTACHTQEHKNSHHIKTKQVAKKKANKKKVSVKESHKKRKGVAGVDFPTDDGFLLTKDSKILSHTDSGIVVAHGNHSHFIFYSDLKGSKFSYLIPNANAKTNKNQAVRNFKAGAVAVNTLNDGYVFNPADIVSEDANGYVVRHGDHFHYIPKASLSQQKQVQASRAVSRLGNQSNSHYRVNSSKIAGLHHPTSDGFLFNGQGIKGTTPTGILVEHHSHLHFISFADLRKGGWGSIADRYQPQKKVDSKKQSPSSKKPRNENTLPKDIKDKLAYLARELHLDISRIRVLKTLNGEIGFEYPHDDHTHVIMAKDIDLSKPIPNPHHDDEDHHKGHHHDESDHKHEEHEHTKSNKLSDEDQKKLIYLAEKLGLNPNQIEVLTSEDGSIIFKYPHDDHSHTIASKDIEIGKPIPDGHHDHSHAKDKVGMATLKQIGFDDEIIQDILHADAPTPFPSNETNPEKMRQWLATVTKINIGQRTNPFQRFGLSLMPNIEVLGIGFTPINDMTPVLQFKKLKQLWMTNTGITDYSFLDKMPLLEGLDISQNGIKDLSFLTKYKQLSLIAAANNGITSLKPLAELPNLQFLVLSHNNISDLTPLSNLTKLQELHLDHNNVKNLSALSGKKDLKVLDLSNNNSADLSTLKTTSLETLLLNETNTSNLSFLKQNPKVSNLTINNAKLSSLDGIEESDEIVKVEAEGNQIKSLVLKNKQGSLKFLNVTNNQLTSLEGVNNYTSLETLSVSKNKLESLDIKTPNKTVTNLDFSHNNVPTSQLKLNEKNIPEAVAKNFPAVVEGSMVGNGSLAEKAAMASKEEKQVSDNTNHQKNTEKSAQANADSKKENPKTHDEHHDHEETDHAHVGHHHH
>NZ_CP007571.1|WP_000180011.1|1009931_1010591_+|HD-domain-containing-protein
MTMVKREDVILNATENMVYHKLKNDPSGHDWFHIVRVRNLAVELAHKEGANTFICQMVALLHDIIDDKICQDSKQASYELTQWLYSQDLTIAEVEHILDILENISFKAGTGLTMKTLEGQIVQDADRLDAMGAIGIARTMAYSGSKGRLIHDPNLKPRENLTLEEYRNGQDTAIMHFYEKLLKLKDLMNTKQGKMLAQKRHDFLELYLAEFYAEWNGKR
>NZ_CP007571.1|WP_000621143.1|1010599_1011064_+|GNAT-family-N-acetyltransferase
MIRRAKEKDLPDIAELLKQILMLHHEVRPDIFHTRGSKFSKEQLKEMLMDESRPIFVYESDEGKVVAHLFLQLQEKRDLPRKSFKTLYIDDLCIDEEVRGQQIGQKLIDFARQYAKKHGCYNITLNVWNDNQRAVSFYEKLGFKPQQTQMEEIL
>NZ_CP007571.1|WP_000665410.1|1011063_1011498_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MKETQEELRQRIGHTAYQVTQNSATEHAFTGKYDDFFEEGIYVDIVSGEVLFSSLDKFQSGCGWPAFSKPIENRMVTNHQDHSHGMHRIEVRSRQADSHLGHVFNDGPVDAGGLRYCINSAALDFIPYDQMAKRGYGDYLSLFD
>NZ_CP007571.1|WP_000168908.1|1011650_1014443_+|cation-transporting-P-type-ATPase
MASTNNVSDTNTRFAKEELEEVFEELGTTQGGLSDEEVAVRQKKYGLNLLSEVKQESIILLFLKNFTSLMAILLWVGGFVAIVSNSLELGLAIWMVNVINGIFSFIQEYRASQATQALKKMLPSYSRVLRKSSEEKILSEQLVPGDIVLIEEGDRISADGRLIKTTDLQVNQSALTGESNPIYKDSNVENDQSKTLIECDNMVFAGTTVSSGSATMVVTAIGMQTQFGQIADLTQGMKSEKSPLQRELDRLTKQISIISITVGIIFFLAATFFVKEPVSKSFIFALGMIVAFIPEGLLPTVTLSLAMAVQRMAKEHALVKKLSSVETLGATSVICSDKTGTLTQNEMTVNRLWQNGKSYQVTGLGYAPEGQILFEGDNICFGNSDRGDLEKLIRFAHLCSNAQVLPPNDDRSTYTVLGDPTEACLNVLLEKSGINRQENRKFAPRLKELPFDSVRKRMTTIHSLGGDEKDKKISITKGAPKEILNLSDYVLSDDKVIPLNKEERNKIQLANDTFAKDGLRVLAVSYCDIEGFSKEQWTQENLEQHMVFIGLIAMSDPPREGVREAIDKCHAASIRIIMVTGDYGLTALSIAKNIGIIRNDNAKVISGLELSEMTDSQLKKELSGEVVFARVAPEQKYRVVTILQEMGEVVAVTGDGVNDAPALKKSDIGVAMGVTGTDVAKESADMILTDDHFASIVHAVEEGRAVYQNIKKFLTYIFNSNTPEAVPSAFFLFSKGFIPLPLTVMQILAVDLGTDMLPALGLGVEPPETDVMNRPPRRLTDRLLDKGLLIKSFLWYGTIESVLAMGGFFWAHYLRYGNFTFFVANGIPYREATTMTLGAIIFSQIGMVMNSRTSYQSIRALSIFGNKLINFGIIMEILAFLVLVYVPPFHNLFNTASLGLSHWLYLISCPFIMIGLDEVRKLFSSRKNKR
>NZ_CP007571.1|WP_000065324.1|1014442_1015546_+|DUF2974-domain-containing-protein
MSNIITYLKNNSNLTFDELALNDVDILCLNEFGYISFEKLINTTEMKSVLVCELYHEYLQTMAKSYSFMFTSQRHDLCQLMMTSKRFKNLTLSYYRAEVSLEFEKQFAAMVFTIPNIDYHQVVFRGTDANLIGWKEDFKLTYMREISAHRSAIKYLNTILPYFDKVVLSGHSKGGNLALYAAMFTKPDLKAKIDLIWLIDSPGLQKTLLPTTEYKTTKQKCIRLLPEESIVGMMLYSDIEPLIISSNARGILQHDVTTWEIQEPAILKTGAGLSLKSICFEKTFQQWMAELKSQERKLFFDLLFDSFLSSGVSSLDDFNLASRAKMMKAFHSFRELDDDKKRLFNKSLKLLVTIFWGAYHDNSRKTK
>NZ_CP007571.1|WP_000146568.1|1015664_1016303_-|CatB-related-O-acetyltransferase
MASILKKHLEKRLELKNDPMRTDMSTGASYPKYGFSVGKYTYGYQQFFYEGVNLKEIGAFCSIAQNVTITGMNHPTDHITTNPFIYYKSRGFINEDRADLIDEKKNGKVIIGNDVWIGTNVTILPSVTIGNGAIIGAGSVITKDIPDYAVVAGKPAKIIKYRFSEEEITLLNASQWWNWSDEAIKEHISEFSDKKEFFNTLKSISENKNHKL
>NZ_CP007571.1|WP_001056394.1|1018550_1019162_+|TVP38/TMEM64-family-protein
MNMKLSKRYRFWQKVIKALGVLALIATLVLVVYLYKLGILNDSNELKDLVHKYEFWGPMIFIVAQIVQIVFPVIPGGVTTVAGFLIFGPTLGFIYNYIGIIIGSVILFWLVKFYGRKFVLLFMDQKTFDKYESKLETSGYEKFFIFCMASPISPADIMVMITGLSNMSIKRFVTIIMITKPISIIGYSYLWIYGGDILKNFLN

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Crispr_ID: NZ_CP007571_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007571_2

1145095-1145165

Orphan

Consensus_repeat	Method
CGTTGACGACGCTCTAGAACATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007571_2

>merge|NZ_CP007571|2|1145095-1145165|CRISPRCasFinder
CGTTGACGACGCTCTAGAACATTACCTTGGCTTCTGTTTTCTGCATCGCGTTGACGACGCTCTAAAACATT

>NZ_CP007571|2|2|1145095-1145165|CRISPRCasFinder
CGTTGACGACGCTCTAGAACATT	ACCTTGGCTTCTGTTTTCTGCATCG
CGTTGACGACGCTCTAAAACATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007571.1\|WP_000845314.1\|1147693_1149364_-\|formate--tetrahydrofolate-ligase	unknown	unknown	gnl\|CDD\|237403
NZ_CP007571.1\|WP_000282561.1\|1155667_1156369_+\|phosphopantothenate--cysteine-ligase	unknown	unknown	gnl\|CDD\|235856
NZ_CP007571.1\|WP_000455156.1\|1154692_1155529_-\|lipoate--protein-ligase-family-protein	unknown	unknown	gnl\|CDD\|319740
NZ_CP007571.1\|WP_000362328.1\|1138494_1139124_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771
NZ_CP007571.1\|WP_000025410.1\|1141322_1142864_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP007571.1\|WP_000280832.1\|1149452_1150472_-\|lipoate--protein-ligase	unknown	unknown	gnl\|CDD\|223173
NZ_CP007571.1\|WP_000826109.1\|1135012_1136089_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237139
NZ_CP007571.1\|WP_000717327.1\|1152156_1152489_-\|glycine-cleavage-system-protein-H	unknown	unknown	gnl\|CDD\|223583
NZ_CP007571.1\|WP_000890175.1\|1139136_1139838_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NZ_CP007571.1\|WP_000542443.1\|1143502_1144579_-\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
NZ_CP007571.1\|WP_000219401.1\|1150498_1151377_-\|NAD-dependent-deacetylase	unknown	unknown	gnl\|CDD\|223915
NZ_CP007571.1\|WP_000638282.1\|1145979_1147575_-\|cardiolipin-synthase	unknown	unknown	gnl\|CDD\|197257
NZ_CP007571.1\|WP_001126465.1\|1131799_1134982_-\|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393
NZ_CP007571.1\|WP_000778223.1\|1152517_1153504_-\|MsnO8-family-LLM-class-oxidoreductase	unknown	unknown	gnl\|CDD\|274646
NZ_CP007571.1\|WP_001165747.1\|1142994_1143333_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236436
NZ_CP007571.1\|WP_001133614.1\|1151345_1152164_-\|protein-ADP-ribose-hydrolase	unknown	unknown	gnl\|CDD\|235225
NZ_CP007571.1\|WP_000275479.1\|1137190_1138483_-\|dihydroorotase	unknown	unknown	gnl\|CDD\|236479
NZ_CP007571.1\|WP_001178657.1\|1140050_1141283_-\|threonine/serine-exporter-family-protein	unknown	unknown	gnl\|CDD\|377697
NZ_CP007571.1\|WP_001016473.1\|1136102_1137026_-\|aspartate-carbamoyltransferase-catalytic-subunit	unknown	unknown	gnl\|CDD\|234849
NZ_CP007571.1\|WP_001067079.1\|1153500_1154700_-\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086

Protein	Function_ID	Function_description	E-value
NZ_CP007571.1\|WP_000845314.1\|1147693_1149364_-\|formate--tetrahydrofolate-ligase	gnl\|CDD\|237403	PRK13505, PRK13505, formate--tetrahydrofolate ligase; Provisional.	0
NZ_CP007571.1\|WP_000282561.1\|1155667_1156369_+\|phosphopantothenate--cysteine-ligase	gnl\|CDD\|235856	PRK06732, PRK06732, phosphopantothenate--cysteine ligase; Validated.	6.93696e-140
NZ_CP007571.1\|WP_000455156.1\|1154692_1155529_-\|lipoate--protein-ligase-family-protein	gnl\|CDD\|319740	cd16435, BPL_LplA_LipB, biotin-lipoate ligase family. This family includes biotin protein ligase (BPL), lipoate-protein ligase A (LplA) and octanoyl-[acyl carrier protein]-protein acyltransferase (LipB). Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine. Lipoate-protein ligase A (LplA) catalyses the formation of an amide linkage between lipoic acid and a specific lysine residue in lipoate dependent enzymes.	4.20812e-71
NZ_CP007571.1\|WP_000362328.1\|1138494_1139124_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	1.94914e-76
NZ_CP007571.1\|WP_000025410.1\|1141322_1142864_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NZ_CP007571.1\|WP_000280832.1\|1149452_1150472_-\|lipoate--protein-ligase	gnl\|CDD\|223173	COG0095, LplA, Lipoate-protein ligase A [Coenzyme metabolism].	1.25622e-82
NZ_CP007571.1\|WP_000826109.1\|1135012_1136089_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
NZ_CP007571.1\|WP_000717327.1\|1152156_1152489_-\|glycine-cleavage-system-protein-H	gnl\|CDD\|223583	COG0509, GcvH, Glycine cleavage system H protein (lipoate-binding) [Amino acid transport and metabolism].	7.35002e-28
NZ_CP007571.1\|WP_000890175.1\|1139136_1139838_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	2.09775e-129
NZ_CP007571.1\|WP_000542443.1\|1143502_1144579_-\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
NZ_CP007571.1\|WP_000219401.1\|1150498_1151377_-\|NAD-dependent-deacetylase	gnl\|CDD\|223915	COG0846, SIR2, NAD-dependent protein deacetylases, SIR2 family [Transcription].	5.11635e-59
NZ_CP007571.1\|WP_000638282.1\|1145979_1147575_-\|cardiolipin-synthase	gnl\|CDD\|197257	cd09160, PLDc_SMU_988_like_2, Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins. Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins. Although SMU_988 and similar proteins have not been functionally characterized, members in this subfamily show high sequence homology to bacterial cardiolipin (CL) synthases, which catalyze the reversible phosphatidyl group transfer between two phosphatidylglycerol molecules to form CL and glycerol. Members of this subfamily contain two HKD motifs (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the phospholipase D (PLD) superfamily. The two motifs may be part of the active site and may be involved in phosphatidyl group transfer.	3.30901e-99
NZ_CP007571.1\|WP_001126465.1\|1131799_1134982_-\|carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NZ_CP007571.1\|WP_000778223.1\|1152517_1153504_-\|MsnO8-family-LLM-class-oxidoreductase	gnl\|CDD\|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	5.85304e-113
NZ_CP007571.1\|WP_001165747.1\|1142994_1143333_-\|hypothetical-protein	gnl\|CDD\|236436	PRK09263, PRK09263, anaerobic ribonucleoside triphosphate reductase; Provisional.	7.78178e-24
NZ_CP007571.1\|WP_001133614.1\|1151345_1152164_-\|protein-ADP-ribose-hydrolase	gnl\|CDD\|235225	PRK04143, PRK04143, protein-ADP-ribose hydrolase.	2.87502e-149
NZ_CP007571.1\|WP_000275479.1\|1137190_1138483_-\|dihydroorotase	gnl\|CDD\|236479	PRK09357, pyrC, dihydroorotase; Validated.	0
NZ_CP007571.1\|WP_001178657.1\|1140050_1141283_-\|threonine/serine-exporter-family-protein	gnl\|CDD\|377697	pfam06738, ThrE, Putative threonine/serine exporter. ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.	7.15572e-53
NZ_CP007571.1\|WP_001016473.1\|1136102_1137026_-\|aspartate-carbamoyltransferase-catalytic-subunit	gnl\|CDD\|234849	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit.	1.53654e-159
NZ_CP007571.1\|WP_001067079.1\|1153500_1154700_-\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	2.99926e-179

>NZ_CP007571.1|WP_000542443.1|1143502_1144579_-|aspartate-semialdehyde-dehydrogenase
MGYTVAIVGATGAVGTQMIRQLEQSKLPIEQVKLLSSSRSAGKILHFKDEAIRVEETTKESFYDVDIALFSAGGSISAKFAPYAVKSGAVVVDNTSYFRQNPDVPLVVPEVNAHAMIGHNGIIACPNCSTIQMMIALEPIRQKWGIERVIVSTYQAVSGSGARAVEETKEQLRQVLNDNLSPDQLIATVLPCSSDQKHYPIAFNALPQIDIFTDNDYTYEEMKMTLETKKIMEDATIKVSATCVRIPVLSGHSESIYIETKELASISEIKKAIANFPGAVLQDLPSQQIYPQAINAVGHRETFVGRIRKDLDQENGVHMWVVSDNLLKGAAWNSVQIAETLHKNGLVKPAKELKFELI
>NZ_CP007571.1|WP_001165747.1|1142994_1143333_-|hypothetical-protein
MQIIKRDGQIVEFDPEKIYQAILKAAQTVYVLDESLRQDLAQVTKKVILDLEDAQVERPTINMIQSLVENRLLDAGYIHTAEHYISYRLQRDLERNGYDDQITVHLHFEKIK
>NZ_CP007571.1|WP_000025410.1|1141322_1142864_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSILEVKNLSHGFGDRAIFENVSFRLLKGEHIGLIGANGEGKSTFMSIVTGHLQPDEGKIEWSKYVTAGYLDQHTVLEEGQTVRDVLRTAFDELFKTEARINDIYISMADDGADVDSLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDSDVTELSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDIPFLNDVINIVYHVENQDLVRYSGDYTNFESVYAMKKAQLEAAYERQQKEIADLQDFVNRNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPSFEFKESRTPGRFIFQAKDLQIGYDRALTKPLNLTFERNQKIAIVGANGIGKTTLLKSLLGIIPPISGNVERGDFIDLGYFEQEVPGGNRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQSKVRFCLLMNRENNVLVLDEPTNHLDVDAKDELKRALKAYKGSILMVCHEPDFYEGWMDDVWDFNQLS
>NZ_CP007571.1|WP_001178657.1|1140050_1141283_-|threonine/serine-exporter-family-protein
MQNDMSVVLRAGKLLIESGAEVYRVEDTMKHFAKALQIENFEAYVVSSSIIASGINRYGKQEAKVCNTDGVTANLGRLEAVNNLSRQIAKQDLVSPEEIVKQLDLIEHQKDYSLLVTLISYFCGAGSFSLALGSSLLDSFSAAVTGLILGYFLNLMESRIHTGFLLTILGSSVVALSANLLYFSGLGEHRSIIILGALMVMVPGAAFVNSVREFSQNNFSTGLALIMSALLICISISAGVAITIEIIPFAEQMTGSFSGVPNTILEIIIRTLMAGLGTIAFSILYHVPKRYFLDLGILGAISWMLYLILWQQFHMDAIAVFFPGLFITYFSRLLAAKRKCPATVFLATSMFPLIPGLSFYRAVYFLLTGADAVAMEYFRSCFVTAFTIAIAISIVQQIPLSFFIRRKMIK
>NZ_CP007571.1|WP_000890175.1|1139136_1139838_-|orotidine-5'-phosphate-decarboxylase
MLEKCPIIALDFSDLASVTTFLEHFPKEELLFVKIGMELYYSEGPSIIRYIKSLGHRIFLDLKLHDIPNTVRSSMSVLAKLGIDMTNVHAAGGVEMMKAAREGLGEGPILLAVTQLTSTSQEQMQVDQHINLSVVDSVCHYAQKAQEAGLDGVVASAQEVKQIKKQTNEHFICLTPGIRPPQTNQLDDQKRTMTPEQARIVGADYIVVGRPITKAENPYQAYLEIKEEWNRIK
>NZ_CP007571.1|WP_000362328.1|1138494_1139124_-|orotate-phosphoribosyltransferase
MDLARQIAMELLDIQAVYLRPQQPFTWASGVKSPIYTDNRVTLSYPETRTLIENGFVKQIQKHFPNVDIIAGTATAGIPHGAIIADKMNLPFAYIRSKAKDHGVGNQIEGRVYSGQKMVIIEDLISTGGSVLEAVTAAQSQGIEVLGVVAIFTYQLAKAEQAFREADIPLVTLTDYNQLIKVAKVNGYITADQLVLLKKFKEDQMNWQS
>NZ_CP007571.1|WP_000275479.1|1137190_1138483_-|dihydroorotase
MYIIKNGLIIDPQSGFNQVSDMLIDQGKIKQISKEIDIKGIPIIDASNKIVAPGLVDIHVHFREPGQTHKENIHTGALSAAVGGFTTVLMMANTNPTISSPEIVKQVKESAAKEAIKIETVATITKSLNGKDLVNFEELLEAGVAGFSDDGIPLTDTKVLQEAMNLARKHDVVLSLHEEDPSLNGVLGINEHIAQKIYHVCGASGLAEYSMIARDAMIAYQTQAKVHIQHLSSSESVEVVDFAQKLGANLTAEVTPQHFSKTENLLLTKGANAKLNPPLRLEKDRQALIDGLKSGVISIIASDHAPHHIMEKAADNISQAPSGMTGLETSLALGITYLVSTKELSMIDFLAKMTCNPAQLYGFDAGYLREGGPADIVIFDQAEERIIKAEFASKSSNSPFIGDKLKGVIHYTICNGEIVYQKDSHAATLV
>NZ_CP007571.1|WP_001016473.1|1136102_1137026_-|aspartate-carbamoyltransferase-catalytic-subunit
MNHQTQTLSLEHFVSLEELSNQEVMSLIKRSIEVKENPSNIGFDKDYYVSNLFFENSTRTHKSFEMAELKLGLKTIEFNADTSSVNKGETLYDTILTMSALGLDVCVIRHPDIDYYKELIASPNIHSAIVNGGDGSGQHPSQSLLDLVTIYEEFGYFKGLKIAIVGDLTHSRVAKSNMQVLKRLGAEIFFSGPKEWYSSQFDEYGQYLPIDQLVDQIDVLMLLRVQHERHDGKGVFSKESYHQQFGLTKERYKHLRDTAIIMHPAPVNRDVEIASDLVEADKARIVKQMSNGVYARIAILEAVLNSR
>NZ_CP007571.1|WP_000826109.1|1135012_1136089_-|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit
MKRLLLLEDGSVFEGEAFGADVETSGEIVFSTGMTGYQESITDQSYNGQIITFTYPLIGNYGINRDDYESIRPTCKGVVIYEWAEYPSNWRQQMTLDEFLKLKGIPGISGIDTRALTKIIRKHGTMKACLINEGNSIHEALENLQKSVLLNDQIEQVSTKLAYASPGVGKNIVLVDFGLKHSILRELSQRQCHITVVPHTTTAQEILNLNPDGVLLSNGPGNPEQLPNALQMIQEIQGKIPIFGICMGHQLFAKANGAKTYKMTFGHRGFNHAVRHLQTGQVDFTSQNHGYAVSREDFPEALFITHEEINDKTVEGVRHKYYPAFSVQFHPDAAPGPHDTSYLFDEFINMIDDFQQKS
>NZ_CP007571.1|WP_001126465.1|1131799_1134982_-|carbamoyl-phosphate-synthase-large-subunit
MPKRTDIRKIMVIGSGPIVIGQAAEFDYSGTQACLSLKEEGYQVVLVNSNPATIMTDKDIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMALSKNGILEELNVELLGTKLSAIDKAEDRDLFKQLMEELNQPIPESEIVNSVEEAIQFAEQIGYPLIVRPAFTLGGTGGGMCDNQEQLVDITTKGLKLSPVTQCLIERSIAGFKEIEYEVMRDAADNALVVCNMENFDPVGIHTGDSIVFAPAQTLSDVENQLLRDASLDIIRALKIEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPITKTTYAMFEPALDYVVAKMPRFPFDKFESGDRKLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVDHIKIADLDNVSDDVLLEKIRKAEDDRLFYLAEALRRHYSIEKLASLTSIDSFFLDKLRVIVELEDLLSKNRLDINILKKVKNKGFSDKAIASLWQINEDQVRNMRKEAGILPVYKMVDTCASEFDSATPYFYSTYAVENESLISDKASILVLGSGPIRIGQGVEFDYATVHSVKAIRESGFEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIDLEKPEGVILQFGGQTAINLAKDLNKAGVKILGTQLEDLDRAENRKQFEATLQALNIPQPPGFTATTEEEAVNAAQKIGYPVLVRPSYVLGGRAMKIVENEEDLRHYMTTAVKASPDHPVLIDAYLIGKECEVDAISDGQNILIPGIMEHIERAGVHSGDSMAVYPPQTLSETIIETIVDYTKRLAIGLNCIGMMNIQFVIKDQKVYVIEVNPRASRTLPFLSKVTHIPMAQVATKVILGDKLCNFTYGYDLYPASDMVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSDINLQKALYKAFEAAYLHMPDYGNIVFTVDDTDKEEALELAKVYQSIGYRIYATQGTAIYFDANGLETVLVGKLGENDRNHIPDLIKNGKIQAVINTVGQNNIDNHDALIIRRSAIEQGVPLFTSLDTAHAMFKVLESRAFTLKVLD
>NZ_CP007571.1|WP_000638282.1|1145979_1147575_-|cardiolipin-synthase
MIWRGEKLISNKVKIVRLLNKSKKSLLRGIFSRTTVIAILLILQLLFLLASYSWLEQYRVWLATVEHILTIGAVLYLVNSEMDALSRVTWLILVMIAPLLGAMFLMYTKFDWGYRGLKQRLETLIDESQIYLEDDPETLNQLKSSTSTTYHLVQYFEKAHGNFPVYRNTDVTFLPTGEAFFEKMKEELLKAKKYIFLEFFIIDEGIMWGEILSILEQKVEEGVEVRILYDGMIEITKLSFDYTKRLEKIGIKAKAFSPISPFISTYYNYRDHRKIVVIDGVVGMTGGVNLADEYINHIELFGHWKDSGIMLKGKAVDSFLLLFLQMWSITEEKMLVAPYLGVHDDLVENEGYVIPYGDSPLDTDKVGENVYIDILNHAREYVYIMTPYLILDSELEHAIQFAAERGVDVRIIMPGIPDKPIPYALAKTYYQALTKSGVKIYEYTPGFVHSKIFLSDNTKAVVGTINLDYRSLYHHFECAVYLYKVDAIQDIYRDYMDTLNKSRLVSLKDINNIPKFQKVIGIVTKTIAPLL
>NZ_CP007571.1|WP_000845314.1|1147693_1149364_-|formate--tetrahydrofolate-ligase
MKTDIEIAQSVALKPIAEIVEQVGIGFDDIELYGKYKAKLSFDKIEAVRSQKVGKLILVTAINPTPAGEGKSTMSIGLADALNKIGKKTMIALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELDIDQRRVIWKRVVDLNDRALRQVIVGLGSPVNGIPREDGFDITVASEIMAILCLATDLSDLKKRLSNIVVAYSRDRKPIYVKDLKIEGALTLILKDAIKPNLVQTIYGTPALVHGGPFANIAHGCNSVLATSTALRLADYVVTEAGFGADLGAEKFLDIKTPNLPTSPDAIVIVATLRALKMHGGVSKEDLSQENVKAVKRGFTNLERHVNNMRQYGVPVVVAINQFTADTESEIATLKTLCSNIDVAVELASVWEDGADGGLELAQTVANVIETQSSNYKRLYNDEDTIEEKIKKIVTKIYGGNKVHFGPKAQIQLKEFSDNGWDKMPICMAKTQYSFSDNPNLLGAPTDFDITVREFVPKTGAGFIVALTGDVLTMPGLPKKPAALNMDVLEDGTAIGLF
>NZ_CP007571.1|WP_000280832.1|1149452_1150472_-|lipoate--protein-ligase
MYLIEPIRNGKRITDGAIALAMQVYILQNVFLDDDILFPYYCDPKVEIGKFQNAVIETNQEYLKEHDIPVVRRDTGGGAVYVDSGAVNICYLMKDHGQFGDFKRAYEPAIKALKTLGASSVEMRGRNDLVIDGKKVSGAAMTIVNGRIYGGYSLLLDVDFDAMEKVLNPNRKKIESKGIKSVRSRVGDIRSHLSEDYRHITTDQFKDLMVCQLLHIDHIDQAKRYHLTEKDWAAIDALADEKYKNWDWNYGNSPQYSYHRDARFPSGTYDFHLEIEKGIITNCRIYGDFFSSKDISDIENLLIGCPMKEELVLEKLSTVSLEDYFGQTSPEEIKAVLFP
>NZ_CP007571.1|WP_000219401.1|1150498_1151377_-|NAD-dependent-deacetylase
MTVWKTLEKTNHSQSEILSQLIEESDAIVVGIGAGMSAADGFTYIGPRFEEAFPDFIAKYQLLDMLQASLYDFEDWEEYWAFQSRFVALNYLDQPVGQAYLDLKDILAKKEYHIITTNADNAFAVADYNLEKVFHIQGEYGLWQCSQHCHQQTYRNDQAIRQMIAQQKDMKIPSNLIPKCPKCDQPFEINKRNEEKGMVEDADFHAQRQRYENFLSQHQNDKVLYLEIGVGHTTPQFIKHPFWRFVSLNENSLFVTLNHKHYRIPQKIRSRSVQLTQHIAELIAEAKKEIIG
>NZ_CP007571.1|WP_001133614.1|1151345_1152164_-|protein-ADP-ribose-hydrolase
MPNQKQLLLAMIEYLRSEKSTDVDDLRTTDLQTVWRALVNQQDPQNISQEYLSLEDRYLSHWWNTQKVKTIDVCHQTVYSNVFTYHGDICLLQVDAIVNAANGKLLGCFIPNHHCIDNHIHTFAGSRLRLACHQLMTQQGRMEAVGQAKLTESYHLPCKYVIHTVGPYVKVDQKPSRIREDLLKSSYKSCLQLAVRANLKTIVFPCISTGEFGFPNQRAAELAVQAILEWQRENQHKLYIIFNTFTPKDQEIYQKLLLKEEIDDSMEDSRKN
>NZ_CP007571.1|WP_000717327.1|1152156_1152489_-|glycine-cleavage-system-protein-H
MKKIANYLLIEKNEERYTISLTPELQDDLGTVGYVEFTDDTNLEVDDVILNIEASKTVMAILSPLTGKVVKVNTAASQEPTLLNSEKADENWLVVLTDVDYAAFEALENA
>NZ_CP007571.1|WP_000778223.1|1152517_1153504_-|MsnO8-family-LLM-class-oxidoreductase
MKLSVLDYGLIDYGKTASDAIQETILLSQEAERLGYHQFWVAEHHGVKAFSISNPELMIMHLANQTKSIKIGSGGIMPLHYSSFKLAETLKTLETCHPNRVSIGLGNSLGTVKVSNALRSLHKAHDYEEVLEELKSWLIDESSSKEPLVQPTLSSFPDLYVLGSGQKSAYLAAKLGLGFTFGVFPFMDKDPLTEAKKLSSLYYHQFEEYYPNKSPNLMVAAFVVIADTSEEAENIAKTLDIWMLGNKDFNEFATFPTIEEANHYQLTPEQKAKIKSNRHRMIVGDPKQVKDSLDALVNASQAEELLLIPLVPGLDQRIKSLKLLSQLY
>NZ_CP007571.1|WP_001067079.1|1153500_1154700_-|NADH-dependent-flavin-oxidoreductase
MNNVQGNLFRPLILPNGLSLENRFVLSPMVTNSSTSEGFVTDDDIAYAVRRAKSAPLQITGAAYVTEYGQLFEYGFSVSKDEDIPGLTKLAKAMKSKGAKAVLQLTHAGRFSSHTLARHGYVYGPSPMQLQSPYPHQVKELTHKDILMIIDEYVQATRRAIQAGFDGVEISSAQRLLIQTFFSTFSNQRKDEYGPQTLTNRCRLGLEVFKAVQKVIREEAESDFILGFRATPEETRGSQIGYSIEEFMEFLEKILAIAQVDYLAIASWGHDVFRNTIRSEGVYKGQLVNQVIFEHFGDRVPIMATGGINSASKVFEALQHAHMVGASTPLVVDPEFLQKIKAKRSDQINLRIKVSDLEGLAIPKASFKDIVPLMDYGESLPKEAREVFRELRSNYREER
>NZ_CP007571.1|WP_000455156.1|1154692_1155529_-|lipoate--protein-ligase-family-protein
MEWQDLAQLPVSIFKDYVTDAQDAEKPFIWTEVFLREINRSNQEIILHIWPMTKTVILGMLDRELPHLELAKKEIISRGYEPVVRNFGGLAVVADEGILNFSLIIPDVFERKLSISDGYLIMVDFIRSIFSDFYQPIEHFEVETSYCPGKFDLSINGKKFAGLAQRRIKNGIAVSIYLSVCGDQKERSRMISDFYKIGLGDTGSPIAYPNVDPEIMANLSDLLDCPMTVEDVIDRMLISLKQVGFNDRLLMIRPDLVAEFDRFQAKSMANKGTVSRDE
>NZ_CP007571.1|WP_000282561.1|1155667_1156369_+|phosphopantothenate--cysteine-ligase
MYNMAMKILITSGGTTEKIDTVRSITNHATGALGKIIAEKYLREGHQVTLVTTKNAIKPESATNLSIFEIEDVDSLIKTLKPLVKEHDILIHSMAVSDYTPVYMADFEKVKSSDDLDTFLRKDNHEGKISSESEYQVLFLKKTPKVISLVKKWNPQIILVGFKLLVNVTKENLFKVARHSLIKNKATFILANDLIDITSKHHIAYLLDHDNVYKATTKEDIAQLIYEKVKKYD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007571_1	1.2\|1003897\|29\|NZ_CP007571\|CRISPRCasFinder	1003897-1003925	29	MK448729	Streptococcus phage Javan31, complete genome	33403-33431	0	1.0
NZ_CP007571_1	1.2\|1003897\|29\|NZ_CP007571\|CRISPRCasFinder	1003897-1003925	29	MK448691	Streptococcus phage Javan17, complete genome	33403-33431	0	1.0
NZ_CP007571_1	1.2\|1003897\|29\|NZ_CP007571\|CRISPRCasFinder	1003897-1003925	29	MK448948	Streptococcus phage Javan46, complete genome	33347-33375	0	1.0
NZ_CP007571_1	1.2\|1003897\|29\|NZ_CP007571\|CRISPRCasFinder	1003897-1003925	29	MK448768	Streptococcus phage Javan47, complete genome	35055-35083	0	1.0
NZ_CP007571_2	2.1\|1145118\|25\|NZ_CP007571\|CRISPRCasFinder	1145118-1145142	25	AP013358	Uncultured Mediterranean phage uvMED DNA, complete genome, group G1, isolate: uvMED-CGR-U-MedDCM-OCT-S27-C45	25656-25680	3	0.88
NZ_CP007571_2	2.1\|1145118\|25\|NZ_CP007571\|CRISPRCasFinder	1145118-1145142	25	MG711463	Faecalibacterium phage FP_oengus, complete genome	52130-52154	4	0.84
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	NZ_CP024772	Bacillus thuringiensis LM1212 plasmid pLM1, complete sequence	40319-40347	6	0.793
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	NZ_LN906635	Lactobacillus reuteri plasmid p53608_1, complete genome, strain ATCC 53608	48868-48896	6	0.793
NZ_CP007571_1	1.4\|1003887\|39\|NZ_CP007571\|CRT	1003887-1003925	39	MK448729	Streptococcus phage Javan31, complete genome	33393-33431	6	0.846
NZ_CP007571_1	1.4\|1003887\|39\|NZ_CP007571\|CRT	1003887-1003925	39	MK448691	Streptococcus phage Javan17, complete genome	33393-33431	6	0.846
NZ_CP007571_1	1.4\|1003887\|39\|NZ_CP007571\|CRT	1003887-1003925	39	MK448948	Streptococcus phage Javan46, complete genome	33337-33375	6	0.846
NZ_CP007571_1	1.4\|1003887\|39\|NZ_CP007571\|CRT	1003887-1003925	39	MK448768	Streptococcus phage Javan47, complete genome	35045-35083	6	0.846
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	NC_020879	Aeromonas phage Aes012, complete genome	134557-134585	7	0.759
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	MH179477	Aeromonas phage 60AhydR15PP, complete genome	133527-133555	7	0.759
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	NC_008208	Aeromonas phage 25, complete genome	134599-134627	7	0.759
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	NC_014635	Aeromonas phage phiAS4, complete genome	33180-33208	7	0.759
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	DQ529280	Aeromonas salmonicida bacteriophage 25, complete genome	134599-134627	7	0.759
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	MF479730	Aeromonas phage AS-gz, complete genome	51898-51926	7	0.759
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	JX306041	Stenotrophomonas phage IME13, complete genome	139584-139612	7	0.759
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	MH179476	Aeromonas phage 50AhydR13PP, complete genome	93640-93668	7	0.759
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	NC_019543	Aeromonas phage Aes508, complete genome	133764-133792	7	0.759
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	CP016197	Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-3, complete sequence	84106-84134	7	0.759
NZ_CP007571_1	1.1\|1003831\|29\|NZ_CP007571\|CRISPRCasFinder	1003831-1003859	29	MF417965	Uncultured Caudovirales phage clone 3S_17, partial genome	3160-3188	7	0.759

1. spacer 1.2|1003897|29|NZ_CP007571|CRISPRCasFinder matches to MK448729 (Streptococcus phage Javan31, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatagtcgcacaaacagcgaacag	CRISPR spacer
aatacaatagtcgcacaaacagcgaacag	Protospacer
*****************************

2. spacer 1.2|1003897|29|NZ_CP007571|CRISPRCasFinder matches to MK448691 (Streptococcus phage Javan17, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatagtcgcacaaacagcgaacag	CRISPR spacer
aatacaatagtcgcacaaacagcgaacag	Protospacer
*****************************

3. spacer 1.2|1003897|29|NZ_CP007571|CRISPRCasFinder matches to MK448948 (Streptococcus phage Javan46, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatagtcgcacaaacagcgaacag	CRISPR spacer
aatacaatagtcgcacaaacagcgaacag	Protospacer
*****************************

4. spacer 1.2|1003897|29|NZ_CP007571|CRISPRCasFinder matches to MK448768 (Streptococcus phage Javan47, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatagtcgcacaaacagcgaacag	CRISPR spacer
aatacaatagtcgcacaaacagcgaacag	Protospacer
*****************************

5. spacer 2.1|1145118|25|NZ_CP007571|CRISPRCasFinder matches to AP013358 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G1, isolate: uvMED-CGR-U-MedDCM-OCT-S27-C45) position: , mismatch: 3, identity: 0.88

accttggcttctgttttctgcatcg	CRISPR spacer
agcttgacttctgttttctgcatct	Protospacer
* ****.*****************

6. spacer 2.1|1145118|25|NZ_CP007571|CRISPRCasFinder matches to MG711463 (Faecalibacterium phage FP_oengus, complete genome) position: , mismatch: 4, identity: 0.84

accttggcttctgttttctgcatcg	CRISPR spacer
gccttggcttcttttttctgcttca	Protospacer
.*********** ******** **.

7. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to NZ_CP024772 (Bacillus thuringiensis LM1212 plasmid pLM1, complete sequence) position: , mismatch: 6, identity: 0.793

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
tgatatgttatttgatgatgtaacattag	Protospacer
**  **************** **** .*

8. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to NZ_LN906635 (Lactobacillus reuteri plasmid p53608_1, complete genome, strain ATCC 53608) position: , mismatch: 6, identity: 0.793

tgcaatgttatttgatgatggaacaacat-	CRISPR spacer
tgcaactttatttgatgatggaa-agtaca	Protospacer
*****. **************** *..*.

9. spacer 1.4|1003887|39|NZ_CP007571|CRT matches to MK448729 (Streptococcus phage Javan31, complete genome) position: , mismatch: 6, identity: 0.846

-attccaaaacaatacaatagtcgcacaaacagcgaacag	CRISPR spacer
tactgc-gattaatacaatagtcgcacaaacagcgaacag	Protospacer
 *.* * .* .*****************************

10. spacer 1.4|1003887|39|NZ_CP007571|CRT matches to MK448691 (Streptococcus phage Javan17, complete genome) position: , mismatch: 6, identity: 0.846

-attccaaaacaatacaatagtcgcacaaacagcgaacag	CRISPR spacer
tactgc-gattaatacaatagtcgcacaaacagcgaacag	Protospacer
 *.* * .* .*****************************

11. spacer 1.4|1003887|39|NZ_CP007571|CRT matches to MK448948 (Streptococcus phage Javan46, complete genome) position: , mismatch: 6, identity: 0.846

-attccaaaacaatacaatagtcgcacaaacagcgaacag	CRISPR spacer
tactgc-gattaatacaatagtcgcacaaacagcgaacag	Protospacer
 *.* * .* .*****************************

12. spacer 1.4|1003887|39|NZ_CP007571|CRT matches to MK448768 (Streptococcus phage Javan47, complete genome) position: , mismatch: 6, identity: 0.846

-attccaaaacaatacaatagtcgcacaaacagcgaacag	CRISPR spacer
tactgc-gattaatacaatagtcgcacaaacagcgaacag	Protospacer
 *.* * .* .*****************************

13. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to NC_020879 (Aeromonas phage Aes012, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

14. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to MH179477 (Aeromonas phage 60AhydR15PP, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

15. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to NC_008208 (Aeromonas phage 25, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

16. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to NC_014635 (Aeromonas phage phiAS4, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

17. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to DQ529280 (Aeromonas salmonicida bacteriophage 25, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

18. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to MF479730 (Aeromonas phage AS-gz, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

19. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to JX306041 (Stenotrophomonas phage IME13, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

20. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to MH179476 (Aeromonas phage 50AhydR13PP, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

21. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to NC_019543 (Aeromonas phage Aes508, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

22. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to CP016197 (Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-3, complete sequence) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
tgatatgttatttgatgatgtaacattgg	Protospacer
**  **************** **** ..

23. spacer 1.1|1003831|29|NZ_CP007571|CRISPRCasFinder matches to MF417965 (Uncultured Caudovirales phage clone 3S_17, partial genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ctcattggtatttgatgatggaacataaa	Protospacer
. ** ** *****************  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

44006 : 52213

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000638884.1\|44006_45461_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.7e-54	32.7
WP_001293628.1\|45488_46514_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	8.1e-64	42.7
WP_000717515.1\|46776_47328_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.7e-26	35.8
WP_000780014.1\|47350_48103_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000166561.1\|48122_49670_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.0e-78	50.2
WP_001045909.1\|49862_50762_+	peptidoglycan DD-metalloendopeptidase family protein	A0A221J6U0	Arthrobacter_phage	4.1e-19	45.9
WP_000783416.1\|50908_52213_+	LysM peptidoglycan-binding domain-containing protein	A0A2D1GNZ3	Streptomyces_phage	4.9e-05	40.5

DBSCAN-SWA_2

309674 : 317196

Bacillus_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000593862.1\|309674_310418_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-29	38.1
WP_000478229.1\|310539_310764_+	DUF4059 family protein	NA	NA	NA	NA
WP_000272353.1\|310832_311747_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.1e-87	52.8
WP_000276183.1\|311904_313365_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.4e-100	42.3
WP_000174854.1\|313361_314183_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	7.7e-73	55.1
WP_041326139.1\|314311_315772_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.5
WP_000041114.1\|315861_317196_+	aminopeptidase C	R4TV59	Phaeocystis_globosa_virus	1.1e-63	33.3

DBSCAN-SWA_3

572204 : 628267

Streptococcus_phage(73.02%)

transposase,integrase,terminase,capsid,portal,tail,holin

attL 578087:578102|attR 615283:615298

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000595706.1\|572204_573401_+	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	3.6e-103	54.5
WP_001068667.1\|573984_574332_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_000264730.1\|574556_575636_-\|integrase	site-specific integrase	A0A1X9IGD8	Lactococcus_phage	3.2e-63	39.8
WP_000505363.1\|575759_575963_-	hypothetical protein	O34033	Streptococcus_phage	1.7e-10	48.4
WP_000891067.1\|576065_576623_-	GTP pyrophosphokinase	Q0H269	Geobacillus_phage	1.6e-18	30.2
WP_041330190.1\|576624_577368_-	helix-turn-helix transcriptional regulator	A0A097PBE5	Streptococcus_pyogenes_phage	4.2e-78	63.7
WP_001107539.1\|577871_578096_-	DUF2188 domain-containing protein	E8ZD70	Streptococcus_phage	2.2e-22	67.6
578087:578102	attL	NA	NA	NA	NA
WP_000039331.1\|578459_579155_-	hypothetical protein	M1PL51	Streptococcus_phage	6.8e-30	41.6
WP_000164461.1\|579208_579424_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001072512.1\|579441_580167_+	phage antirepressor protein	A0A141E1D3	Streptococcus_phage	7.2e-107	81.2
WP_032459526.1\|580235_580460_+	hypothetical protein	A0A1S5SC19	Streptococcus_phage	2.3e-24	79.5
WP_000884083.1\|580394_581201_-	TIGR02391 family protein	A0A1S5SBU1	Streptococcus_phage	4.2e-124	82.8
WP_000360288.1\|581341_581677_-	hypothetical protein	J7KDN7	Streptococcus_phage	7.8e-16	69.1
WP_000263688.1\|581821_582007_+	helix-turn-helix transcriptional regulator	J7KH19	Streptococcus_phage	7.8e-26	95.1
WP_000879944.1\|582079_582310_+	hypothetical protein	NA	NA	NA	NA
WP_000972073.1\|582465_583227_+	DnaD domain protein	A0A097PBE7	Streptococcus_pyogenes_phage	1.7e-71	64.4
WP_000600244.1\|583213_583996_+	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	3.1e-132	88.8
WP_000431578.1\|584122_584398_+	hypothetical protein	J7KJY6	Streptococcus_phage	1.2e-41	96.7
WP_000229414.1\|584384_584639_+	hypothetical protein	J7KK18	Streptococcus_phage	5.7e-35	83.3
WP_000064172.1\|584803_585757_+	recombinase RecT	J7KDK3	Streptococcus_phage	5.1e-121	71.0
WP_000163581.1\|585753_586551_+	hypothetical protein	J7KGZ1	Streptococcus_phage	2.1e-131	84.9
WP_000435056.1\|586719_587061_+	hypothetical protein	M1PKX3	Streptococcus_phage	2.2e-13	42.0
WP_000067995.1\|587057_587570_+	hypothetical protein	A0A1S5S8V7	Streptococcus_phage	7.6e-63	72.0
WP_000127438.1\|587556_587754_+	hypothetical protein	A3F626	Streptococcus_phage	2.6e-11	91.9
WP_000954649.1\|587747_588032_+	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	1.1e-47	95.7
WP_000743215.1\|588028_588298_+	hypothetical protein	Q938M2	Temperate_phage	1.0e-42	91.0
WP_000612739.1\|588311_588728_+	hypothetical protein	Q938M1	Temperate_phage	3.2e-35	61.3
WP_000205525.1\|588724_589009_+	hypothetical protein	A3F628	Streptococcus_phage	4.9e-35	81.9
WP_001019149.1\|589152_589665_+	DUF1642 domain-containing protein	A0A097PAV5	Streptococcus_pyogenes_phage	2.7e-28	46.0
WP_001105090.1\|589685_589985_+	hypothetical protein	M1PFH6	Streptococcus_phage	1.3e-17	45.4
WP_000221696.1\|590172_590367_+	hypothetical protein	NA	NA	NA	NA
WP_000660741.1\|590363_590630_+	hypothetical protein	NA	NA	NA	NA
WP_000533372.1\|591024_591450_+	DUF1492 domain-containing protein	A0A0B5A564	Streptococcus_phage	2.9e-31	50.0
WP_000225343.1\|591743_592121_+	HNH endonuclease	Q7Y4J1	Streptococcus_phage	9.3e-42	71.3
WP_000725957.1\|592272_592629_+	hypothetical protein	A0A0B5A7G9	Streptococcus_phage	5.9e-22	49.6
WP_001108671.1\|592625_593894_+\|portal	phage portal protein	M1PFL4	Streptococcus_phage	1.1e-187	77.1
WP_000227332.1\|593886_595107_+	hypothetical protein	Q7Y4I9	Streptococcus_phage	2.1e-114	66.3
WP_000421992.1\|595106_595295_+	hypothetical protein	NA	NA	NA	NA
WP_000256853.1\|595403_596819_+\|terminase	terminase	A0A0B5A091	Streptococcus_phage	6.3e-216	74.8
WP_041330192.1\|596899_597364_+	DUF4355 domain-containing protein	A0A0B5A7G6	Streptococcus_phage	4.4e-41	51.3
WP_000841023.1\|597366_598269_+\|capsid	phage major capsid protein	A0A0B5A5W3	Streptococcus_phage	9.7e-146	86.0
WP_000640308.1\|598265_598481_+	hypothetical protein	M1PRX2	Streptococcus_phage	3.2e-07	49.3
WP_000180798.1\|598494_598917_+	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	2.4e-46	68.6
WP_025194588.1\|598876_599215_+	hypothetical protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.9
WP_000032787.1\|599207_599444_+	hypothetical protein	A0A1P8BMT2	Lactococcus_phage	2.5e-21	66.7
WP_000573598.1\|599444_599780_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_000226353.1\|599789_600347_+\|tail	tail protein	M1PKG8	Streptococcus_phage	3.4e-64	65.8
WP_000858406.1\|600346_600592_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	9.7e-16	55.3
WP_000916437.1\|600606_600978_+	DUF5361 domain-containing protein	A0A1P8BMT6	Lactococcus_phage	9.5e-31	54.0
WP_000224695.1\|600977_602990_+	hypothetical protein	Q9F4J3	Streptococcus_phage	9.8e-13	58.9
WP_000228809.1\|602983_604516_+	hypothetical protein	J7KH53	Streptococcus_phage	4.7e-201	73.6
WP_000955554.1\|604516_608632_+	CHAP domain-containing protein	J7KBT9	Streptococcus_phage	0.0e+00	82.9
WP_000214864.1\|608644_610630_+	hypothetical protein	J7KK23	Streptococcus_phage	0.0e+00	85.2
WP_000494205.1\|610655_610985_+	DUF1366 domain-containing protein	J7KDI9	Streptococcus_phage	7.2e-22	54.3
WP_000698337.1\|610959_611172_+	hypothetical protein	J7KDP6	Streptococcus_phage	2.1e-14	60.0
WP_000215499.1\|611184_611487_+	hypothetical protein	X2KT07	Streptococcus_phage	2.2e-25	59.6
WP_001001961.1\|611488_611824_+\|holin	phage holin	A0A1P8VVK6	Streptococcus_phage	3.6e-37	72.1
WP_000236382.1\|611825_612545_+	CHAP domain-containing protein	A0A1U9WRD0	Streptococcus_virus	7.2e-59	70.3
WP_000965654.1\|613455_613635_+	hypothetical protein	J7KBZ4	Streptococcus_phage	3.6e-20	81.4
WP_079218646.1\|613734_614349_-\|integrase	site-specific integrase	F8HGP4	Streptococcus_phage	9.2e-55	60.7
WP_001881173.1\|614351_614618_-	hypothetical protein	Q77YW7	Streptococcus_phage	7.1e-20	65.2
WP_000809083.1\|614794_615022_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001122305.1\|615183_615384_+\|transposase	IS3 family transposase	NA	NA	NA	NA
615283:615298	attR	NA	NA	NA	NA
WP_001865698.1\|615405_615666_+\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	3.4e-11	43.0
WP_001867107.1\|615791_616001_+\|transposase	transposase	A0A0C5AEA5	Paenibacillus_phage	1.4e-15	55.4
WP_000508795.1\|616173_616335_-	TM2 domain-containing protein	NA	NA	NA	NA
WP_000594360.1\|617077_618355_+	ABC transporter permease	NA	NA	NA	NA
WP_000353149.1\|618364_619021_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-22	31.8
WP_041330194.1\|619020_620397_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_000699093.1\|620493_621147_+	response regulator transcription factor	W8CYM9	Bacillus_phage	8.1e-25	33.6
WP_000734169.1\|621143_622463_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.2e-05	25.9
WP_000076708.1\|623339_623540_+	CsbD family protein	J7KJ36	Streptococcus_phage	8.4e-26	97.0
WP_000027835.1\|623581_623770_+	hypothetical protein	J7KIW4	Streptococcus_phage	3.3e-16	78.2
WP_041330030.1\|623986_625438_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.5
WP_000078930.1\|625758_626964_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_000564843.1\|627133_628267_+\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

1303877 : 1371949

Bacillus_phage(18.18%)

tRNA,protease,integrase,transposase

attL 1319848:1319866|attR 1362187:1362205

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000365673.1\|1303877_1304561_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_000221658.1\|1304664_1305345_-	DnaD domain-containing protein	Q938N2	Temperate_phage	1.9e-08	31.8
WP_000365343.1\|1305462_1305981_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	4.6e-31	44.1
WP_001247526.1\|1306103_1308668_-	hypothetical protein	NA	NA	NA	NA
WP_000622242.1\|1308819_1311018_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-72	28.9
WP_000124588.1\|1311014_1311776_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000405386.1\|1311777_1312707_-	ribonuclease Z	NA	NA	NA	NA
WP_000568323.1\|1312748_1313396_-	cystathionine beta-lyase	NA	NA	NA	NA
WP_000573350.1\|1313388_1314627_-	GTPase HflX	NA	NA	NA	NA
WP_001226483.1\|1314717_1315608_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_000239229.1\|1315718_1315895_+	DUF3042 family protein	NA	NA	NA	NA
WP_041330263.1\|1316026_1317484_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.5
WP_000800370.1\|1317502_1318420_-	TDT family transporter	NA	NA	NA	NA
WP_000823039.1\|1318554_1322313_-	pullulanase	NA	NA	NA	NA
1319848:1319866	attL	NA	NA	NA	NA
WP_001205494.1\|1322481_1323216_-	hypothetical protein	NA	NA	NA	NA
WP_000130593.1\|1323230_1323815_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_000150956.1\|1323911_1325318_-	dipeptidase PepV	NA	NA	NA	NA
WP_000670189.1\|1325364_1325967_-	NAD(P)H nitroreductase	NA	NA	NA	NA
WP_000942620.1\|1326136_1327918_+	glycerophosphodiester phosphodiesterase	I6XE30	Staphylococcus_phage	9.3e-07	25.0
WP_041330265.1\|1327959_1329741_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_000567585.1\|1329899_1330667_+	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_000285046.1\|1330725_1332066_-	MATE family efflux transporter	NA	NA	NA	NA
WP_000245056.1\|1332165_1332582_-	VOC family protein	NA	NA	NA	NA
WP_000582587.1\|1332585_1333083_-	hypothetical protein	NA	NA	NA	NA
WP_000162275.1\|1333304_1333901_+	Lj965 prophage superinfection immunity protein	NA	NA	NA	NA
WP_094248916.1\|1334089_1335194_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	3.7e-70	48.9
WP_000754577.1\|1337028_1339497_-	pneumococcal-type histidine triad protein	NA	NA	NA	NA
WP_000715197.1\|1339509_1340430_-	metal ABC transporter substrate-binding lipoprotein/laminin-binding adhesin Lmb	NA	NA	NA	NA
WP_000564843.1\|1340607_1341741_-\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_001227857.1\|1341991_1345444_-	C5a peptidase ScpA/B	A0A218KC60	Bacillus_phage	7.6e-05	39.4
WP_000007459.1\|1348423_1350238_-	hypothetical protein	A0A0A7RWA3	Clostridium_phage	5.0e-32	31.9
WP_000248019.1\|1350653_1351889_+	hypothetical protein	NA	NA	NA	NA
WP_001284550.1\|1352090_1353272_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_000198709.1\|1353289_1353523_-	DUF3173 family protein	NA	NA	NA	NA
WP_000031192.1\|1353526_1354093_-	hypothetical protein	NA	NA	NA	NA
WP_000581744.1\|1354842_1355352_-	hypothetical protein	NA	NA	NA	NA
WP_000161972.1\|1355415_1355919_-	hypothetical protein	NA	NA	NA	NA
WP_000857661.1\|1355918_1356233_-	hypothetical protein	NA	NA	NA	NA
WP_000884910.1\|1356467_1357673_-	hypothetical protein	NA	NA	NA	NA
WP_001129984.1\|1357724_1358216_-	hypothetical protein	NA	NA	NA	NA
WP_000974945.1\|1358229_1361841_-	N-6 DNA methylase	A0A1B1IUC6	uncultured_Mediterranean_phage	1.9e-06	24.3
WP_001196976.1\|1362081_1362447_-	50S ribosomal protein L7/L12	NA	NA	NA	NA
1362187:1362205	attR	NA	NA	NA	NA
WP_001287285.1\|1362510_1363011_-	50S ribosomal protein L10	NA	NA	NA	NA
WP_000002804.1\|1363444_1365553_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	8.2e-119	37.4
WP_000532330.1\|1365646_1366591_-	homocysteine S-methyltransferase	NA	NA	NA	NA
WP_000120090.1\|1368101_1368752_-	HXXEE domain-containing protein	NA	NA	NA	NA
WP_000140673.1\|1369505_1370135_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000796925.1\|1370115_1370712_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_000918412.1\|1370722_1371949_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	8.1e-135	60.0

DBSCAN-SWA_5

1624644 : 1636945

Streptococcus_phage(85.71%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000767486.1\|1624644_1625472_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.1e-124	78.0
WP_041326615.1\|1625493_1626951_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.5
WP_000287943.1\|1627080_1627437_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.2e-42	72.6
WP_000966769.1\|1627438_1627915_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.6e-38	50.9
WP_041330272.1\|1627970_1629152_-	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	2.0e-167	75.1
WP_001198082.1\|1629213_1629762_-	GNAT family acetyltransferase	M1PSC3	Streptococcus_phage	1.4e-54	57.9
WP_000158397.1\|1629830_1630922_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	3.9e-165	78.0
WP_000603271.1\|1631054_1631690_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_001867099.1\|1631959_1632823_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.1e-109	70.4
WP_000358198.1\|1632828_1633155_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.2e-30	61.1
WP_000364568.1\|1633185_1634049_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.5e-74	50.0
WP_000715592.1\|1634068_1634704_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.8e-67	61.1
WP_001144242.1\|1634792_1635452_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	8.0e-65	56.5
WP_000178150.1\|1635470_1636181_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-18	28.5
WP_001185985.1\|1636180_1636945_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.6e-14	24.8

DBSCAN-SWA_6

1846916 : 1870878

Streptococcus_phage(85.0%)

integrase

attL 1842518:1842534|attR 1860023:1860039

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1842518:1842534	attL	NA	NA	NA	NA
WP_001238594.1\|1846916_1847591_-	response regulator transcription factor	W8CYM9	Bacillus_phage	9.5e-29	33.2
WP_000831903.1\|1847946_1848081_-	50S ribosomal protein L34	NA	NA	NA	NA
WP_000712236.1\|1848264_1849620_-	YjiH family protein	NA	NA	NA	NA
WP_001291561.1\|1849864_1851082_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|1851163_1851367_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_000857133.1\|1851827_1852058_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000804885.1\|1852054_1852477_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_001227347.1\|1852981_1853335_+	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000336323.1\|1853394_1853562_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_000691750.1\|1853680_1855600_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A2K5B2A5	Erysipelothrix_phage	0.0e+00	99.5
WP_001814923.1\|1855615_1855732_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224320.1\|1855976_1856912_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	7.7e-170	99.0
WP_000769868.1\|1856908_1857910_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_000804748.1\|1857906_1860084_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
1860023:1860039	attR	NA	NA	NA	NA
WP_000331160.1\|1860086_1862534_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000506270.1\|1862517_1863024_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|1862998_1863496_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|1863612_1863834_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000398284.1\|1863876_1865082_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_000879507.1\|1865104_1865257_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|1865259_1866645_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|1866673_1867060_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|1867075_1867390_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000429367.1\|1867908_1869636_-	ABC transporter permease/substrate binding protein	NA	NA	NA	NA
WP_000181801.1\|1869654_1870878_-	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.6e-29	37.0

DBSCAN-SWA_7

2154524 : 2164016

Streptococcus_phage(81.82%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000038826.1\|2154524_2154902_-	DUF1492 domain-containing protein	Q7Y4J3	Streptococcus_phage	3.2e-10	37.9
WP_000891152.1\|2155035_2155524_-	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	3.5e-49	59.3
WP_001258765.1\|2155596_2156154_-	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	2.4e-30	59.8
WP_000694573.1\|2156311_2156485_-	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	4.3e-10	56.1
WP_001069293.1\|2156481_2156739_-	hypothetical protein	NA	NA	NA	NA
WP_000656430.1\|2157031_2158426_-	hypothetical protein	W8CQP1	Croceibacter_phage	3.7e-43	33.7
WP_001029296.1\|2158437_2159295_-	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	3.0e-120	72.9
WP_001100460.1\|2159295_2159568_-	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	1.8e-18	56.8
WP_001157003.1\|2159908_2160100_-	hypothetical protein	NA	NA	NA	NA
WP_001256559.1\|2160102_2160324_-	hypothetical protein	NA	NA	NA	NA
WP_000877499.1\|2160320_2160653_-	hypothetical protein	NA	NA	NA	NA
WP_001259478.1\|2160729_2161236_-	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	4.5e-07	35.4
WP_000130289.1\|2161324_2161498_-	hypothetical protein	NA	NA	NA	NA
WP_001021393.1\|2161596_2162235_-	Bro-N domain-containing protein	NA	NA	NA	NA
WP_001258609.1\|2162470_2163073_-	phage repressor protein	A0A1W6JPC3	Staphylococcus_phage	6.7e-42	46.7
WP_000909285.1\|2163088_2163274_-	hypothetical protein	A0A1X9I5U7	Streptococcus_phage	6.2e-07	54.8
WP_001080836.1\|2163428_2164016_+	helix-turn-helix domain-containing protein	A0A1X9I5U6	Streptococcus_phage	4.0e-15	37.5

DBSCAN-SWA_8

2178574 : 2190653

Streptococcus_phage(44.44%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041326845.1\|2178574_2180029_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.5
WP_001042657.1\|2180223_2180928_-	transglycosylase SLT domain-containing protein	A0A2H4J6C5	uncultured_Caudovirales_phage	6.4e-28	65.3
WP_000029072.1\|2181033_2181573_-	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	3.0e-17	46.4
WP_041330291.1\|2181788_2182583_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000510606.1\|2182575_2183418_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	2.0e-15	28.5
WP_000181757.1\|2183393_2184233_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	3.5e-20	30.0
WP_000239225.1\|2184232_2184775_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_000217756.1\|2184897_2186181_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	2.2e-05	23.6
WP_000706187.1\|2186182_2187427_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	6.3e-87	41.3
WP_000384868.1\|2187665_2188019_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	9.4e-20	61.8
WP_000264865.1\|2188021_2189131_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_017771557.1\|2189240_2190653_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.7e-208	76.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007571

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection